# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- COPI_assoc PF08507.10 EGC28226.1 - 4.2e-18 65.6 4.4 6e-18 65.1 4.4 1.2 1 0 0 1 1 1 1 COPI associated protein PEN-2 PF10251.9 EGC28226.1 - 0.028 14.8 0.5 0.079 13.4 0.3 1.9 2 0 0 2 2 2 0 Presenilin enhancer-2 subunit of gamma secretase Annexin PF00191.20 EGC28227.1 - 2.4e-39 133.2 6.0 6.5e-12 45.3 0.1 4.2 4 0 0 4 4 4 4 Annexin Cohesin_load PF10345.9 EGC28228.1 - 3.5e-06 25.8 0.9 6e-06 25.0 0.2 1.7 1 1 0 2 2 2 1 Cohesin loading factor Spy1 PF11357.8 EGC28228.1 - 0.076 13.3 1.2 0.16 12.3 0.8 1.7 1 1 1 2 2 2 0 Cell cycle regulatory protein PTS_IIB PF02302.17 EGC28228.1 - 0.12 13.1 0.2 4.1 8.2 0.2 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit FNIP PF05725.12 EGC28231.1 - 1.1e-41 140.7 54.5 9.1e-09 35.4 0.1 9.4 2 2 5 9 9 9 9 FNIP Repeat MATH PF00917.26 EGC28234.1 - 0.00031 20.9 0.8 0.00039 20.5 0.8 1.3 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.18 EGC28235.1 - 3.6e-18 66.0 18.4 2.4e-13 50.5 7.3 3.9 2 1 3 5 5 5 3 TRAF-type zinc finger Sina PF03145.16 EGC28235.1 - 9.2e-07 29.0 22.4 0.00077 19.5 2.3 3.6 1 1 2 3 3 3 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC28235.1 - 0.0012 19.3 22.9 0.0031 17.9 7.9 3.7 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 EGC28235.1 - 0.0028 17.5 5.7 0.0028 17.5 5.7 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGC28235.1 - 0.014 15.4 2.7 0.014 15.4 2.7 3.0 2 1 1 3 3 3 0 Double zinc ribbon ZapB PF06005.12 EGC28235.1 - 0.05 14.0 1.5 0.25 11.8 1.5 2.2 1 0 0 1 1 1 0 Cell division protein ZapB Whi5 PF08528.11 EGC28235.1 - 0.17 11.5 2.5 0.81 9.4 0.1 2.5 2 0 0 2 2 2 0 Whi5 like JIP_LZII PF16471.5 EGC28235.1 - 0.69 10.1 7.6 0.56 10.4 4.2 2.6 2 1 0 2 2 2 0 JNK-interacting protein leucine zipper II zf_C2HC_14 PF18574.1 EGC28235.1 - 1 9.2 0.0 1 9.2 0.0 5.7 6 0 0 6 6 6 0 C2HC Zing finger domain DMPK_coil PF08826.10 EGC28235.1 - 5.3 7.2 6.6 3 8.0 0.7 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like GATA PF00320.27 EGC28236.1 - 7.2e-14 51.1 2.9 2e-13 49.7 2.9 1.8 1 0 0 1 1 1 1 GATA zinc finger PfkB PF00294.24 EGC28237.1 - 6.9e-06 25.6 0.0 8.1e-06 25.3 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PseudoU_synth_2 PF00849.22 EGC28238.1 - 6.3e-30 104.4 0.0 6.3e-30 104.4 0.0 3.0 2 1 1 3 3 3 1 RNA pseudouridylate synthase S4 PF01479.25 EGC28238.1 - 0.034 13.9 0.2 0.078 12.7 0.2 1.6 1 0 0 1 1 1 0 S4 domain Ras PF00071.22 EGC28239.1 - 1e-18 67.4 0.5 1.3e-18 67.1 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28239.1 - 1.3e-08 35.1 0.3 2.6e-08 34.1 0.3 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase STATa_Ig PF18214.1 EGC28240.1 - 5.7e-05 23.1 3.4 7.7e-05 22.7 0.3 2.6 1 1 2 3 3 3 2 STATa Immunoglobulin-like domain DUF4834 PF16118.5 EGC28241.1 - 0.0063 17.4 6.3 0.0063 17.4 6.3 4.6 1 1 1 3 3 3 1 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 EGC28241.1 - 0.13 13.1 0.5 0.59 10.9 0.5 2.2 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal SSP160 PF06933.11 EGC28241.1 - 0.22 9.7 7.5 0.32 9.2 7.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pkinase_Tyr PF07714.17 EGC28243.1 - 2.3e-24 86.1 0.0 7.3e-22 77.9 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGC28243.1 - 9e-23 81.0 0.2 4.1e-22 78.8 0.1 1.8 1 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EGC28243.1 - 0.0026 17.4 0.0 0.0046 16.6 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGC28243.1 - 0.0027 17.1 0.0 0.0034 16.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC28243.1 - 0.004 16.0 0.0 0.007 15.2 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase CAF1 PF04857.20 EGC28247.1 - 5.3e-21 75.1 0.2 4.4e-10 39.2 0.0 2.5 1 1 1 2 2 2 2 CAF1 family ribonuclease Aminotran_3 PF00202.21 EGC28248.1 - 2.7e-115 385.3 0.0 3.1e-115 385.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.21 EGC28248.1 - 0.00043 19.6 0.0 0.00076 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Homeodomain PF00046.29 EGC28249.1 - 8.6e-18 63.9 4.2 4.6e-10 39.2 0.6 2.8 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC28249.1 - 0.00048 20.0 0.1 0.00048 20.0 0.1 3.6 4 0 0 4 4 4 2 Homeobox KN domain YniB PF14002.6 EGC28249.1 - 0.14 11.9 0.1 0.3 10.8 0.1 1.5 1 0 0 1 1 1 0 YniB-like protein Peptidase_M50 PF02163.22 EGC28250.1 - 5e-18 65.3 0.1 9.1e-18 64.4 0.1 1.4 1 0 0 1 1 1 1 Peptidase family M50 PDZ PF00595.24 EGC28250.1 - 0.00091 19.5 0.0 0.0023 18.2 0.0 1.6 1 0 0 1 1 1 1 PDZ domain DUF3446 PF11928.8 EGC28250.1 - 0.0099 16.2 4.3 0.02 15.2 4.3 1.4 1 0 0 1 1 1 1 Early growth response N-terminal domain ORMDL PF04061.14 EGC28250.1 - 0.01 15.6 0.3 0.01 15.6 0.3 1.9 2 0 0 2 2 2 0 ORMDL family ATP1G1_PLM_MAT8 PF02038.16 EGC28250.1 - 0.044 13.2 0.2 0.044 13.2 0.2 2.7 3 0 0 3 3 3 0 ATP1G1/PLM/MAT8 family PDZ_6 PF17820.1 EGC28250.1 - 0.086 12.7 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 PDZ domain DUF5470 PF17564.2 EGC28250.1 - 0.15 12.2 5.2 0.73 10.1 5.8 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5470) CRAL_TRIO PF00650.20 EGC28251.1 - 1.3e-46 158.2 0.3 2.2e-46 157.5 0.3 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGC28251.1 - 8e-10 39.0 0.2 1.1e-09 38.5 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGC28251.1 - 3.2e-08 33.6 0.1 9e-08 32.2 0.1 1.8 1 0 0 1 1 1 1 CRAL/TRIO, N-terminal domain SpoVIF PF14069.6 EGC28252.1 - 0.0041 16.9 3.2 0.096 12.5 0.0 3.3 3 1 0 3 3 3 2 Stage VI sporulation protein F vATP-synt_AC39 PF01992.16 EGC28253.1 - 3.9e-111 371.8 3.7 4.6e-111 371.5 3.7 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CH PF00307.31 EGC28254.1 - 1.4e-17 63.8 0.0 1.6e-17 63.7 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC28254.1 - 0.00024 20.9 0.1 0.00029 20.6 0.1 1.3 1 1 0 1 1 1 1 CAMSAP CH domain Methyltransf_28 PF02636.17 EGC28255.1 - 3.5e-68 230.1 0.0 4.9e-68 229.6 0.0 1.2 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PI31_Prot_N PF11566.8 EGC28256.1 - 1.2e-16 60.9 0.0 1.8e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.11 EGC28256.1 - 1.1e-14 55.3 16.7 1.1e-14 55.3 16.7 3.0 4 0 0 4 4 4 1 PI31 proteasome regulator Pkinase PF00069.25 EGC28257.1 - 1.7e-55 188.2 0.0 2e-55 188.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28257.1 - 1.8e-23 83.1 0.0 2.4e-23 82.8 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC28257.1 - 2.2e-06 27.2 0.0 2.9e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC28257.1 - 0.013 15.4 0.0 0.45 10.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGC28257.1 - 0.03 13.9 0.1 0.069 12.7 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Kdo PF06293.14 EGC28257.1 - 0.051 12.9 0.0 0.066 12.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGC28257.1 - 0.052 12.6 0.0 0.082 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 zf-RING_2 PF13639.6 EGC28259.1 - 2.6e-09 37.3 8.9 6.4e-09 36.0 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC28259.1 - 3.8e-09 36.3 5.7 7.2e-09 35.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC28259.1 - 1.8e-08 34.1 8.9 3.4e-08 33.2 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC28259.1 - 8.9e-07 28.7 9.9 2.5e-06 27.3 9.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC28259.1 - 2.6e-06 27.4 5.0 5.8e-06 26.2 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC28259.1 - 4.7e-05 23.3 7.3 0.00012 22.0 7.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC28259.1 - 0.0005 19.8 7.7 0.0014 18.4 7.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC28259.1 - 0.00055 20.0 9.1 0.0015 18.6 9.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC28259.1 - 0.0013 18.5 8.4 0.0032 17.2 8.4 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC28259.1 - 0.0024 18.1 5.1 0.0074 16.6 5.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC28259.1 - 0.0085 15.9 1.8 0.019 14.8 1.8 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGC28259.1 - 0.018 14.9 7.2 0.041 13.7 7.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4834 PF16118.5 EGC28259.1 - 0.021 15.8 1.4 0.021 15.8 1.4 4.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Zn_ribbon_17 PF17120.5 EGC28259.1 - 0.08 12.6 3.9 0.18 11.5 3.9 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EGC28259.1 - 0.41 10.7 5.1 1 9.5 4.9 1.7 1 1 0 1 1 1 0 Double zinc ribbon DDE_Tnp_4 PF13359.6 EGC28261.1 - 1.9e-09 37.4 0.1 2.8e-09 36.8 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC28261.1 - 0.00087 19.0 0.0 0.0016 18.1 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain Pyridoxal_deC PF00282.19 EGC28261.1 - 0.038 12.7 0.0 0.051 12.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain TraI_2_C PF07515.11 EGC28261.1 - 0.046 13.7 0.4 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term DUF3642 PF12182.8 EGC28261.1 - 6.4 7.1 9.0 0.47 10.8 0.8 2.7 2 0 0 2 2 2 0 Bacterial lipoprotein Hydrolase_4 PF12146.8 EGC28262.1 - 0.00034 20.0 0.0 0.00037 19.9 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Arb2 PF09757.9 EGC28262.1 - 0.0032 16.6 0.1 0.0038 16.4 0.1 1.1 1 0 0 1 1 1 1 Arb2 domain Ser_hydrolase PF06821.13 EGC28262.1 - 0.0033 17.3 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_1 PF00561.20 EGC28262.1 - 0.0055 16.4 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF900 PF05990.12 EGC28262.1 - 0.014 14.9 0.0 0.017 14.7 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 EGC28262.1 - 0.021 14.4 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) DUF676 PF05057.14 EGC28262.1 - 0.04 13.4 0.1 0.054 13.0 0.1 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EGC28262.1 - 0.053 13.4 0.0 0.082 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_6 PF12697.7 EGC28262.1 - 0.11 13.1 0.0 0.12 12.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SIP1 PF04938.12 EGC28263.1 - 2e-66 223.9 15.6 3.4e-66 223.1 15.6 1.4 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) RRN3 PF05327.11 EGC28263.1 - 0.024 13.2 5.6 0.039 12.5 5.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CDC45 PF02724.14 EGC28263.1 - 0.12 10.7 7.3 0.15 10.3 7.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGC28263.1 - 0.15 10.2 12.8 0.2 9.8 12.8 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EGC28263.1 - 6.6 5.4 6.5 8.6 5.0 6.5 1.1 1 0 0 1 1 1 0 Presenilin PTPRCAP PF15713.5 EGC28263.1 - 8.3 6.7 10.6 15 5.9 10.6 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Presenilin PF01080.17 EGC28265.1 - 6.5e-93 311.6 41.9 1.7e-66 224.7 22.8 2.8 1 1 2 3 3 3 2 Presenilin DUF5582 PF17819.1 EGC28265.1 - 1.1 9.7 4.3 4 7.9 4.5 1.7 2 0 0 2 2 2 0 Family of unknown function (DUF5582) SUIM_assoc PF16619.5 EGC28266.1 - 0.019 15.1 5.6 0.019 15.1 5.6 2.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF2101 PF09874.9 EGC28266.1 - 0.089 12.5 6.0 0.15 11.7 6.0 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) Com_YlbF PF06133.11 EGC28266.1 - 0.26 11.9 10.7 0.18 12.4 8.3 1.9 2 0 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Androgen_recep PF02166.16 EGC28266.1 - 6.8 5.4 8.9 9.2 5.0 8.9 1.1 1 0 0 1 1 1 0 Androgen receptor ATP-synt PF00231.19 EGC28267.1 - 3.1e-35 122.3 0.0 3.5e-35 122.1 0.0 1.0 1 0 0 1 1 1 1 ATP synthase DUF2057 PF09829.9 EGC28271.1 - 0.15 12.2 0.1 2.8 8.1 0.0 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2057) PH PF00169.29 EGC28274.1 - 2.7e-31 108.2 11.8 9.1e-18 64.7 1.2 4.2 4 0 0 4 4 4 2 PH domain LIM PF00412.22 EGC28274.1 - 2.3e-22 78.9 26.3 1.5e-10 41.1 4.4 3.5 3 0 0 3 3 3 3 LIM domain PH_11 PF15413.6 EGC28274.1 - 2.4e-06 27.9 18.6 0.0075 16.7 6.5 4.9 3 2 0 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.6 EGC28274.1 - 5.2e-05 23.5 0.2 0.00023 21.4 0.2 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EGC28274.1 - 0.00019 21.8 3.7 5.9 7.3 0.0 4.5 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.6 EGC28274.1 - 0.0006 19.9 0.3 0.0006 19.9 0.3 3.2 4 0 0 4 4 4 1 PH domain PH_13 PF16652.5 EGC28274.1 - 0.042 13.6 0.1 0.042 13.6 0.1 3.0 3 0 0 3 3 3 0 Pleckstrin homology domain PH_6 PF15406.6 EGC28274.1 - 0.084 13.2 2.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain Cyclin PF08613.11 EGC28276.1 - 1.4e-05 25.6 2.4 1.4e-05 25.6 2.4 3.1 2 2 1 3 3 3 1 Cyclin Vir_act_alpha_C PF10400.9 EGC28276.1 - 0.56 10.9 5.0 1.7 9.4 0.2 2.4 2 0 0 2 2 2 0 Virulence activator alpha C-term Rab5ip PF07019.12 EGC28278.1 - 3.4e-15 56.4 6.2 4.5e-15 56.0 6.2 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2892 PF11127.8 EGC28278.1 - 0.047 13.7 0.5 0.094 12.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) DUF4231 PF14015.6 EGC28278.1 - 0.14 12.6 0.6 0.2 12.1 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) FNIP PF05725.12 EGC28279.1 - 4.9e-43 145.0 47.1 1.2e-11 44.6 0.4 10.5 7 2 5 13 13 13 9 FNIP Repeat Nbl1_Borealin_N PF10444.9 EGC28279.1 - 0.04 13.6 0.0 0.31 10.7 0.0 2.5 3 0 0 3 3 3 0 Nbl1 / Borealin N terminal HIT PF01230.23 EGC28284.1 - 1.2e-25 90.1 0.0 1.6e-25 89.6 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGC28284.1 - 4.6e-08 33.5 0.0 6.3e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding ARTD15_N PF18084.1 EGC28285.1 - 1.9e-11 44.1 3.6 2.1e-11 43.9 0.5 2.5 2 1 0 2 2 2 1 ARTD15 N-terminal domain PARP PF00644.20 EGC28285.1 - 1.6e-05 24.6 11.3 0.00014 21.5 11.3 2.5 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain ABC2_membrane_3 PF12698.7 EGC28285.1 - 0.027 13.6 19.0 0.071 12.2 6.7 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein RIFIN PF02009.16 EGC28285.1 - 0.55 10.1 8.1 0.21 11.4 1.4 2.1 2 0 0 2 2 2 0 Rifin Presenilin PF01080.17 EGC28285.1 - 0.75 8.5 3.9 0.48 9.1 0.8 1.9 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 EGC28285.1 - 3.4 6.8 5.7 0.26 10.5 0.5 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter Peptidase_M56 PF05569.11 EGC28285.1 - 4.4 6.4 6.9 0.39 9.9 0.7 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Orf78 PF06024.12 EGC28285.1 - 5.5 7.3 18.6 1.4 9.3 7.7 3.2 2 1 0 2 2 2 0 Orf78 (ac78) UQ_con PF00179.26 EGC28286.1 - 2.2e-43 147.2 0.0 2.5e-43 147.1 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme GPDPase_memb PF10110.9 EGC28288.1 - 0.016 14.0 8.0 0.03 13.1 8.0 1.4 1 0 0 1 1 1 0 Membrane domain of glycerophosphoryl diester phosphodiesterase STAT_bind PF02864.15 EGC28288.1 - 0.98 10.0 8.9 0.13 12.8 1.9 2.3 2 0 0 2 2 2 0 STAT protein, DNA binding domain DUF2701 PF10857.8 EGC28288.1 - 2.6 8.2 13.4 8.6 6.5 4.4 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) MRP-L20 PF12824.7 EGC28289.1 - 3.2e-05 24.1 1.1 9e-05 22.7 0.2 2.1 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 GPCR_chapero_1 PF11904.8 EGC28290.1 - 2e-56 191.7 2.7 2.6e-56 191.3 2.7 1.1 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.7 EGC28290.1 - 1.9e-08 34.8 0.1 0.00041 20.9 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC28290.1 - 3.1e-05 24.4 0.0 5.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC28290.1 - 0.00074 19.8 0.0 0.0015 18.8 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC28290.1 - 0.0034 17.8 0.1 0.016 15.6 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_3 PF13606.6 EGC28290.1 - 0.012 16.1 0.0 0.42 11.3 0.0 2.7 2 0 0 2 2 2 0 Ankyrin repeat SAE2 PF08573.10 EGC28291.1 - 2.1e-09 38.5 3.6 9.3e-08 33.2 0.3 5.1 2 1 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus DUF3450 PF11932.8 EGC28291.1 - 8.5 5.6 11.2 0.059 12.7 1.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) Presenilin PF01080.17 EGC28292.1 - 0.76 8.5 5.4 1.2 7.8 5.4 1.4 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGC28292.1 - 3.9 6.6 4.6 6.8 5.8 4.6 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter F-box-like PF12937.7 EGC28294.1 - 1e-10 41.3 0.6 2.6e-10 40.0 0.6 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC28294.1 - 1.4e-06 28.0 0.3 4e-06 26.6 0.3 1.9 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGC28294.1 - 0.00019 21.3 0.0 0.00074 19.4 0.0 2.0 1 0 0 1 1 1 1 F-box WD40 PF00400.32 EGC28294.1 - 0.0016 19.2 0.0 0.0073 17.1 0.0 2.3 1 0 0 1 1 1 1 WD domain, G-beta repeat TRAP-delta PF05404.12 EGC28294.1 - 0.071 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Translocon-associated protein, delta subunit precursor (TRAP-delta) ANAPC4_WD40 PF12894.7 EGC28294.1 - 0.09 13.1 0.0 0.77 10.1 0.0 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGC28294.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 PQQ-like domain PQQ PF01011.21 EGC28294.1 - 0.15 12.0 0.1 18 5.5 0.0 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat SprA-related PF12118.8 EGC28294.1 - 1 8.5 7.7 2.8 7.0 7.7 1.7 1 0 0 1 1 1 0 SprA-related family Homeodomain PF00046.29 EGC28295.1 - 3.5e-10 39.6 7.9 5e-06 26.3 0.1 2.8 3 0 0 3 3 3 2 Homeodomain Homeobox_KN PF05920.11 EGC28295.1 - 3.2e-07 30.1 0.8 0.014 15.3 0.1 2.7 2 1 0 2 2 2 2 Homeobox KN domain HSP20 PF00011.21 EGC28296.1 - 1.1e-15 57.6 0.7 8.2e-15 54.8 0.7 1.9 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC28296.1 - 0.0068 16.0 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF4974 PF16344.5 EGC28296.1 - 0.036 14.1 1.7 0.041 13.9 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4974) DUF4834 PF16118.5 EGC28298.1 - 0.00061 20.7 5.9 0.00061 20.7 5.9 4.6 2 1 2 4 4 4 1 Domain of unknown function (DUF4834) Metallophos_2 PF12850.7 EGC28299.1 - 4.2e-24 85.6 0.1 4.9e-24 85.4 0.1 1.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGC28299.1 - 0.0085 16.6 0.2 5.5 7.4 0.1 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase FHA PF00498.26 EGC28301.1 - 0.00016 22.0 0.2 0.00037 20.8 0.1 1.6 2 0 0 2 2 2 1 FHA domain DUF4033 PF13225.6 EGC28301.1 - 0.0035 17.3 0.2 0.0045 17.0 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4033) GP24_25 PF17388.2 EGC28301.1 - 0.17 11.9 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 Tail assembly gene products 24 & 25 Nop25 PF09805.9 EGC28302.1 - 0.55 10.7 11.9 1.5 9.2 11.9 1.7 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NOA36 PF06524.12 EGC28302.1 - 5.9 6.1 9.8 8.9 5.5 9.8 1.2 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 EGC28302.1 - 6.8 5.3 12.2 11 4.6 12.2 1.4 1 0 0 1 1 1 0 Presenilin RRM_1 PF00076.22 EGC28303.1 - 4.8e-17 61.5 0.0 7.8e-17 60.9 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGC28303.1 - 0.061 13.3 0.0 0.11 12.4 0.0 1.5 1 0 0 1 1 1 0 RL domain RRM_occluded PF16842.5 EGC28303.1 - 0.089 12.7 0.0 0.26 11.2 0.0 1.8 1 1 1 2 2 2 0 Occluded RNA-recognition motif RRM_Rrp7 PF17799.1 EGC28303.1 - 0.1 12.4 0.0 3 7.6 0.0 2.1 1 1 1 2 2 2 0 Rrp7 RRM-like N-terminal domain PH PF00169.29 EGC28304.1 - 2.8e-13 50.3 10.2 2.3e-06 28.1 6.6 3.2 1 1 1 2 2 2 2 PH domain PH_8 PF15409.6 EGC28304.1 - 7.3e-08 32.6 4.3 4.8e-05 23.6 0.4 3.3 2 1 1 3 3 3 2 Pleckstrin homology domain PH_11 PF15413.6 EGC28304.1 - 0.0061 17.0 12.4 0.0061 17.0 12.4 3.3 3 1 0 3 3 3 1 Pleckstrin homology domain GTP1_OBG PF01018.22 EGC28304.1 - 0.17 11.4 3.3 0.15 11.7 0.7 2.0 1 1 1 2 2 2 0 GTP1/OBG MRP-L27 PF09809.9 EGC28305.1 - 3.2e-13 49.5 0.5 3.8e-13 49.2 0.5 1.1 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 ABC_membrane_2 PF06472.15 EGC28306.1 - 4.6e-47 160.7 6.1 6.7e-42 143.8 5.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGC28306.1 - 2.5e-17 63.7 0.3 7.6e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGC28306.1 - 8.5e-05 22.2 1.1 0.023 14.5 0.1 2.9 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 EGC28306.1 - 0.00087 18.5 0.0 0.0018 17.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGC28306.1 - 0.0015 18.5 0.0 0.0051 16.7 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGC28306.1 - 0.014 15.8 0.0 0.036 14.4 0.0 1.6 2 0 0 2 2 1 0 AAA ATPase domain IstB_IS21 PF01695.17 EGC28306.1 - 0.039 13.7 0.0 0.098 12.4 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.26 EGC28306.1 - 0.073 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGC28306.1 - 0.087 12.2 0.0 0.16 11.3 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Polbeta PF18765.1 EGC28306.1 - 0.13 12.4 8.9 2.1 8.5 0.4 4.1 3 0 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase AAA_18 PF13238.6 EGC28306.1 - 0.53 10.8 5.3 2.2 8.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain WD40 PF00400.32 EGC28308.1 - 2.3e-11 44.0 3.5 2.5e-05 25.0 0.1 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC28308.1 - 1.8e-05 25.0 0.0 0.00026 21.2 0.0 2.5 1 1 2 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC28308.1 - 0.062 12.2 0.0 0.15 11.0 0.0 1.6 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Methyltransf_31 PF13847.6 EGC28309.1 - 1e-14 54.6 0.1 2.2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain PrmC_N PF17827.1 EGC28309.1 - 2.2e-11 44.2 0.0 7.3e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 PrmC N-terminal domain MTS PF05175.14 EGC28309.1 - 1.5e-07 31.1 0.0 3.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGC28309.1 - 1.1e-06 29.2 0.0 3.6e-06 27.6 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGC28309.1 - 1.7e-05 24.5 0.0 8e-05 22.3 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EGC28309.1 - 4.4e-05 24.2 0.3 0.00048 20.8 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGC28309.1 - 7.3e-05 22.6 0.1 0.00016 21.5 0.1 1.5 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC28309.1 - 0.001 19.0 0.0 0.0037 17.1 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGC28309.1 - 0.0011 18.4 0.0 0.0023 17.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.10 EGC28309.1 - 0.0013 18.3 0.1 0.003 17.2 0.0 1.7 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase N6_Mtase PF02384.16 EGC28309.1 - 0.0016 17.8 0.0 0.0034 16.7 0.0 1.5 1 0 0 1 1 1 1 N-6 DNA Methylase UPF0020 PF01170.18 EGC28309.1 - 0.0024 17.6 0.0 0.0046 16.7 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_10 PF05971.12 EGC28309.1 - 0.0082 15.5 0.0 0.018 14.4 0.0 1.5 1 1 0 1 1 1 1 RNA methyltransferase Methyltransf_11 PF08241.12 EGC28309.1 - 0.0082 16.8 0.0 0.02 15.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.11 EGC28309.1 - 0.012 16.1 0.0 0.044 14.3 0.0 2.0 1 0 0 1 1 1 0 Eco57I restriction-modification methylase PCMT PF01135.19 EGC28309.1 - 0.014 15.2 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) N6-adenineMlase PF10237.9 EGC28309.1 - 0.017 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase MetW PF07021.12 EGC28309.1 - 0.073 12.7 0.1 0.22 11.1 0.1 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Staphylokinase PF02821.16 EGC28312.1 - 0.013 15.9 3.3 0.023 15.2 3.3 1.4 1 0 0 1 1 1 0 Staphylokinase/Streptokinase family Lig_chan PF00060.26 EGC28314.1 - 0.17 11.7 2.6 15 5.4 2.7 2.5 2 0 0 2 2 2 0 Ligand-gated ion channel UbiA PF01040.18 EGC28315.1 - 0.0005 19.5 5.8 0.00068 19.0 5.8 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Entericidin PF08085.11 EGC28316.1 - 0.044 13.8 0.6 0.097 12.7 0.6 1.5 1 0 0 1 1 1 0 Entericidin EcnA/B family DUF4615 PF15393.6 EGC28317.1 - 1.1e-08 35.8 0.2 1.1e-08 35.8 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) PGA2 PF07543.12 EGC28317.1 - 0.37 10.8 10.5 0.13 12.2 6.8 1.9 2 0 0 2 2 2 0 Protein trafficking PGA2 MDM10 PF12519.8 EGC28317.1 - 3 6.6 10.9 3.6 6.4 10.9 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 GREB1 PF15782.5 EGC28317.1 - 3.5 4.6 14.4 4 4.4 14.4 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Neur_chan_memb PF02932.16 EGC28317.1 - 8.4 6.4 7.4 9.9 6.1 7.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TPR_1 PF00515.28 EGC28318.1 - 3.3e-23 80.5 8.3 7e-11 41.5 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC28318.1 - 1.9e-18 65.0 5.2 3.2e-08 33.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC28318.1 - 1e-16 59.7 8.0 8.6e-09 34.9 0.3 4.1 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC28318.1 - 6e-16 57.9 11.5 5.7e-08 32.3 1.0 3.3 1 1 2 3 3 3 3 TPR repeat SGTA_dimer PF16546.5 EGC28318.1 - 9.4e-14 51.0 1.0 9.4e-14 51.0 1.0 1.9 2 0 0 2 2 1 1 Homodimerisation domain of SGTA TPR_17 PF13431.6 EGC28318.1 - 3.4e-10 39.6 6.3 0.00011 22.4 0.1 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC28318.1 - 8e-09 34.9 0.4 0.00024 20.9 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC28318.1 - 3.8e-08 33.5 1.5 1.1e-06 28.9 0.7 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC28318.1 - 1e-07 32.2 0.0 0.0004 21.0 0.0 3.6 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC28318.1 - 9.2e-07 29.4 0.1 7.2e-06 26.6 0.1 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC28318.1 - 1.7e-05 25.3 3.6 1.8e-05 25.1 0.2 2.7 4 0 0 4 4 2 1 Tetratricopeptide repeat TOM20_plant PF06552.12 EGC28318.1 - 3e-05 23.9 3.7 6.1e-05 22.8 0.4 2.9 3 1 0 3 3 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.6 EGC28318.1 - 3.6e-05 24.1 1.4 0.011 16.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC28318.1 - 0.00016 21.5 2.6 0.024 14.5 0.2 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC28318.1 - 0.00019 21.5 0.0 0.17 12.1 0.0 2.3 1 1 1 2 2 2 2 Tetratricopeptide repeat BTAD PF03704.17 EGC28318.1 - 0.0036 17.7 0.0 0.026 14.9 0.0 2.1 1 1 0 1 1 1 1 Bacterial transcriptional activator domain ANAPC3 PF12895.7 EGC28318.1 - 0.019 15.2 2.9 0.038 14.2 2.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGC28318.1 - 0.027 13.7 0.1 0.24 10.6 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF5388 PF17363.2 EGC28318.1 - 0.044 14.0 0.7 0.14 12.4 0.1 2.2 3 0 0 3 3 1 0 Family of unknown function (DUF5388) TPR_21 PF09976.9 EGC28318.1 - 0.057 13.1 2.0 0.25 11.0 0.4 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain DUF3856 PF12968.7 EGC28318.1 - 0.072 13.2 0.6 3 7.9 0.6 2.7 1 1 0 1 1 1 0 Domain of Unknown Function (DUF3856) PPR PF01535.20 EGC28318.1 - 0.087 13.1 3.0 0.2 12.0 0.0 3.0 3 0 0 3 3 2 0 PPR repeat MIT PF04212.18 EGC28318.1 - 0.1 12.7 16.4 0.44 10.6 0.7 4.8 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain 14-3-3 PF00244.20 EGC28318.1 - 2 7.9 9.0 0.097 12.2 1.5 2.3 3 0 0 3 3 2 0 14-3-3 protein UQ_con PF00179.26 EGC28319.1 - 1.4e-41 141.4 0.2 1.6e-41 141.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C PF00481.21 EGC28320.1 - 3.3e-72 243.2 0.0 3.3e-72 243.2 0.0 2.1 2 0 0 2 2 2 1 Protein phosphatase 2C G-alpha PF00503.20 EGC28320.1 - 1.1e-50 172.8 2.4 1.1e-50 172.8 2.4 1.7 2 0 0 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 EGC28320.1 - 0.037 13.8 0.0 0.093 12.5 0.0 1.7 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Androgen_recep PF02166.16 EGC28320.1 - 10 4.9 19.1 1.1 8.0 6.9 2.3 2 0 0 2 2 2 0 Androgen receptor STATa_Ig PF18214.1 EGC28321.1 - 7.9e-49 164.7 0.9 7.9e-49 164.7 0.9 3.2 4 0 0 4 4 4 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 EGC28321.1 - 6.5e-40 135.5 0.7 2.3e-39 133.7 0.7 2.0 1 0 0 1 1 1 1 EF-hand fold domain Dict-STAT-coil PF09267.10 EGC28321.1 - 1.5e-38 131.7 16.7 1.5e-38 131.7 16.7 4.5 4 1 0 4 4 4 1 Dictyostelium STAT, coiled coil SH2 PF00017.24 EGC28321.1 - 2.4e-11 43.5 0.0 9.1e-11 41.7 0.0 2.0 1 0 0 1 1 1 1 SH2 domain PH_4 PF15404.6 EGC28321.1 - 0.021 14.7 3.3 0.088 12.6 3.3 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Pkinase PF00069.25 EGC28322.1 - 3.7e-63 213.3 0.3 6.3e-63 212.6 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28322.1 - 7.4e-39 133.6 0.0 1e-38 133.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC28322.1 - 3.1e-10 39.9 0.0 6.4e-09 35.5 0.0 2.2 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGC28322.1 - 2.1e-05 23.5 0.1 0.00014 20.8 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase DUF1768 PF08719.11 EGC28323.1 - 1.7e-35 122.6 0.1 2e-35 122.4 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sel1 PF08238.12 EGC28324.1 - 1.9e-26 91.9 6.8 1.4e-06 28.8 0.1 6.8 7 0 0 7 7 7 6 Sel1 repeat TPR_2 PF07719.17 EGC28324.1 - 0.48 10.7 9.3 7.9 6.9 0.2 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC28324.1 - 0.76 9.7 11.0 15 5.6 0.7 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGC28324.1 - 8.6 6.1 13.2 0.46 10.2 2.1 3.9 4 0 0 4 4 4 0 TPR repeat Erf4 PF10256.9 EGC28325.1 - 0.086 12.9 0.3 0.1 12.7 0.3 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF725 PF05267.12 EGC28327.1 - 0.0017 18.3 3.5 0.0019 18.1 3.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF725) MRG PF05712.13 EGC28328.1 - 9.9e-45 152.3 2.6 1.8e-44 151.5 2.6 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.8 EGC28328.1 - 2.8e-09 36.7 2.9 5.5e-09 35.8 2.9 1.5 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.17 EGC28328.1 - 0.0036 17.7 0.6 0.0036 17.7 0.6 2.3 3 0 0 3 3 3 1 PWWP domain Presenilin PF01080.17 EGC28328.1 - 0.083 11.6 5.6 0.11 11.3 5.6 1.2 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC28328.1 - 0.17 10.2 9.6 0.2 9.9 9.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RPN2_C PF18004.1 EGC28328.1 - 0.27 11.2 8.0 0.47 10.3 8.0 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain Zip PF02535.22 EGC28328.1 - 0.71 9.0 2.2 0.85 8.8 2.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PGA2 PF07543.12 EGC28328.1 - 0.72 9.8 10.6 1.4 8.9 10.6 1.4 1 0 0 1 1 1 0 Protein trafficking PGA2 MMR_HSR1_Xtn PF16897.5 EGC28331.1 - 3e-41 139.7 0.2 6.3e-41 138.7 0.2 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain TGS PF02824.21 EGC28331.1 - 1.6e-21 76.1 0.0 2.9e-21 75.3 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.23 EGC28331.1 - 1.7e-20 73.2 0.0 5.8e-20 71.5 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC28331.1 - 1.1e-10 41.3 0.2 3.4e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGC28331.1 - 0.0093 16.0 0.4 4 7.5 0.0 2.5 1 1 1 2 2 2 2 Dynamin family MeaB PF03308.16 EGC28331.1 - 0.011 14.8 0.6 0.025 13.6 0.2 1.7 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRPRB PF09439.10 EGC28331.1 - 0.037 13.5 0.1 0.071 12.5 0.1 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit FN3_7 PF18447.1 EGC28332.1 - 0.14 12.5 3.5 0.25 11.7 3.5 1.5 1 0 0 1 1 1 0 Fibronectin type III domain SARAF PF06682.12 EGC28333.1 - 6.3e-65 220.0 12.9 1.3e-64 219.0 12.9 1.5 1 1 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis CRA PF06589.11 EGC28333.1 - 0.098 12.8 3.5 0.42 10.7 1.7 2.2 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) MRAP PF15183.6 EGC28333.1 - 0.12 12.3 1.8 0.23 11.4 0.6 2.2 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family DUF1190 PF06693.11 EGC28333.1 - 1.8 8.9 10.8 0.061 13.7 4.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1190) SUIM_assoc PF16619.5 EGC28334.1 - 0.044 13.8 10.1 1.6 8.8 0.6 2.4 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1548 PF07579.11 EGC28336.1 - 0.048 14.0 6.3 0.073 13.4 6.3 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) RecR PF02132.15 EGC28336.1 - 0.4 10.3 2.3 2.9 7.5 0.0 2.9 4 0 0 4 4 4 0 RecR protein Noelin-1 PF12308.8 EGC28336.1 - 4.2 7.4 8.8 6.8 6.7 2.3 2.1 1 1 1 2 2 2 0 Neurogenesis glycoprotein UQ_con PF00179.26 EGC28337.1 - 9.2e-46 155.0 0.1 1.2e-45 154.5 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF592 PF04574.13 EGC28337.1 - 0.013 15.3 0.0 0.025 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Prok-E2_B PF14461.6 EGC28337.1 - 0.036 13.8 0.0 0.091 12.5 0.0 1.7 1 1 0 1 1 1 0 Prokaryotic E2 family B UFC1 PF08694.11 EGC28337.1 - 0.13 11.9 0.0 0.27 10.9 0.0 1.4 1 0 0 1 1 1 0 Ubiquitin-fold modifier-conjugating enzyme 1 Cwf_Cwc_15 PF04889.12 EGC28337.1 - 1.8 8.2 11.3 2.4 7.8 11.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EGC28337.1 - 4.4 6.6 11.8 5.3 6.3 11.8 1.2 1 0 0 1 1 1 0 NOA36 protein Peptidase_C1 PF00112.23 EGC28338.1 - 9.5e-50 169.7 0.9 1.1e-49 169.5 0.9 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGC28338.1 - 0.0023 16.8 0.3 0.031 13.1 0.1 2.0 2 0 0 2 2 2 2 Peptidase C1-like family Acyltransferase PF01553.21 EGC28339.1 - 2e-12 46.9 0.0 3.9e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase ANAPC4 PF12896.7 EGC28340.1 - 1.9e-37 128.8 8.9 3.7e-37 127.8 8.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 ANAPC4_WD40 PF12894.7 EGC28340.1 - 2.2e-10 40.7 0.6 1.2e-09 38.3 0.2 2.4 2 1 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain Cyclin PF08613.11 EGC28342.1 - 1.1e-33 116.9 0.6 1.1e-33 116.9 0.6 2.6 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGC28342.1 - 2.7e-13 49.7 0.2 6.1e-13 48.6 0.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain NOA36 PF06524.12 EGC28342.1 - 1.7 7.9 9.1 2.6 7.3 9.1 1.2 1 0 0 1 1 1 0 NOA36 protein Lung_7-TM_R PF06814.13 EGC28343.1 - 2e-36 125.8 17.0 2.9e-36 125.2 17.0 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor SirB PF04247.12 EGC28343.1 - 4.8 7.3 12.8 7 6.8 4.8 2.8 2 1 0 2 2 2 0 Invasion gene expression up-regulator, SirB Ham1p_like PF01725.16 EGC28344.1 - 2.2e-40 138.6 0.0 2.5e-40 138.4 0.0 1.0 1 0 0 1 1 1 1 Ham1 family FNIP PF05725.12 EGC28345.1 - 1.2e-18 67.0 38.8 1.9e-05 24.7 0.3 6.3 4 1 1 6 6 6 5 FNIP Repeat FNIP PF05725.12 EGC28346.1 - 2.6e-35 120.3 88.5 0.00018 21.6 1.1 14.4 7 3 6 16 16 16 14 FNIP Repeat zf-B_box PF00643.24 EGC28346.1 - 0.00041 20.4 7.7 0.00075 19.6 7.7 1.4 1 0 0 1 1 1 1 B-box zinc finger HSBP1 PF06825.12 EGC28346.1 - 0.075 12.9 0.2 0.17 11.8 0.2 1.6 1 0 0 1 1 1 0 Heat shock factor binding protein 1 zf-UBR PF02207.20 EGC28346.1 - 0.18 12.0 2.8 0.36 11.0 2.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) IMD PF08397.11 EGC28346.1 - 0.34 10.3 7.3 0.57 9.5 7.3 1.3 1 0 0 1 1 1 0 IRSp53/MIM homology domain Noelin-1 PF12308.8 EGC28346.1 - 0.39 10.7 2.1 0.88 9.6 1.7 1.8 1 1 0 1 1 1 0 Neurogenesis glycoprotein PSDC PF12588.8 EGC28346.1 - 2.7 8.0 7.0 0.62 10.0 0.9 2.7 2 0 0 2 2 2 0 Phophatidylserine decarboxylase Herpes_UL14 PF03580.14 EGC28346.1 - 4.8 7.4 7.0 2.5 8.3 4.8 1.6 1 1 0 1 1 1 0 Herpesvirus UL14-like protein Acetyltransf_1 PF00583.25 EGC28347.1 - 1.6e-16 60.6 0.0 2e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC28347.1 - 5.5e-14 52.2 0.0 6.4e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC28347.1 - 1.8e-12 47.5 0.1 2.7e-12 46.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC28347.1 - 3.5e-05 23.7 0.0 5.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGC28347.1 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.7 EGC28347.1 - 0.0007 19.8 0.3 0.0011 19.2 0.3 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC28347.1 - 0.0012 18.9 0.0 0.0043 17.1 0.0 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC28347.1 - 0.0018 17.8 2.5 0.0024 17.4 2.5 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase PanZ PF12568.8 EGC28347.1 - 0.0032 17.2 0.0 0.004 16.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_3 PF13302.7 EGC28347.1 - 0.0035 18.0 0.0 0.004 17.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGC28347.1 - 0.051 13.7 0.0 0.065 13.4 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Carb_kinase PF01256.17 EGC28347.1 - 0.16 11.4 0.0 0.21 11.1 0.0 1.2 1 0 0 1 1 1 0 Carbohydrate kinase DUF3439 PF11921.8 EGC28349.1 - 9.3 6.2 9.3 4.5 7.2 6.4 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Nup88 PF10168.9 EGC28350.1 - 1.5e-09 36.3 20.6 1.8e-09 36.1 20.6 1.0 1 0 0 1 1 1 1 Nuclear pore component Nup54 PF13874.6 EGC28350.1 - 0.01 15.9 8.5 0.023 14.8 7.8 1.9 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 CoA_binding_2 PF13380.6 EGC28350.1 - 0.03 14.8 0.0 0.049 14.1 0.0 1.3 1 0 0 1 1 1 0 CoA binding domain HrpB7 PF09486.10 EGC28350.1 - 0.052 13.9 1.8 5.3 7.4 0.4 2.2 2 0 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF4795 PF16043.5 EGC28350.1 - 0.15 11.6 14.9 0.23 11.0 14.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) eIF3_N PF09440.10 EGC28350.1 - 0.49 10.8 11.8 0.1 13.1 4.9 2.6 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain Sec3_C_2 PF15278.6 EGC28350.1 - 1.1 9.7 9.0 0.44 10.9 0.4 3.4 1 1 4 5 5 5 0 Sec3 exocyst complex subunit XhlA PF10779.9 EGC28350.1 - 1.6 9.0 16.4 0.41 10.9 2.5 3.3 3 0 0 3 3 3 0 Haemolysin XhlA Atg14 PF10186.9 EGC28350.1 - 4 6.4 18.2 1.1e+02 1.7 18.2 2.2 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF1664 PF07889.12 EGC28350.1 - 4.6 7.3 10.9 8.9 6.4 3.4 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Caldesmon PF02029.15 EGC28351.1 - 2.3 6.9 35.7 3.7 6.2 35.7 1.2 1 0 0 1 1 1 0 Caldesmon Nbl1_Borealin_N PF10444.9 EGC28354.1 - 0.019 14.6 1.0 0.052 13.2 0.1 2.2 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal PRANC PF09372.10 EGC28354.1 - 4.3 7.7 16.9 0.94 9.8 10.1 2.5 1 1 0 2 2 2 0 PRANC domain Lactamase_B_6 PF16661.5 EGC28355.1 - 2.1e-10 40.3 9.5 1.3e-09 37.8 0.5 4.2 4 1 0 4 4 4 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EGC28355.1 - 9.2e-09 35.6 0.0 3e-08 33.9 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Beta_lactamase3 PF17030.5 EGC28355.1 - 2.8e-07 30.0 8.5 3.3e-07 29.8 0.0 3.6 3 1 1 4 4 4 1 Putative beta-lactamase-like family TFIIA PF03153.13 EGC28355.1 - 0.07 13.1 11.5 0.11 12.4 11.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Glyco_transf_49 PF13896.6 EGC28356.1 - 7.6e-47 160.3 4.0 3.1e-28 99.1 0.1 3.2 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan Glycos_transf_2 PF00535.26 EGC28356.1 - 0.1 12.4 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family 2 bZIP_C PF12498.8 EGC28356.1 - 0.47 11.5 3.4 1.2 10.1 3.4 1.7 1 0 0 1 1 1 0 Basic leucine-zipper C terminal TRAM_LAG1_CLN8 PF03798.16 EGC28357.1 - 2.2e-21 76.5 28.3 2.7e-21 76.2 28.3 1.1 1 0 0 1 1 1 1 TLC domain PSP1 PF04468.12 EGC28357.1 - 0.11 12.8 1.5 0.12 12.7 0.2 1.8 2 0 0 2 2 2 0 PSP1 C-terminal conserved region GST_N_4 PF17172.4 EGC28358.1 - 5.3e-19 68.8 0.0 9e-19 68.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain GST_C_6 PF17171.4 EGC28358.1 - 1.1e-17 63.6 0.0 2.2e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Tom37 PF10568.9 EGC28358.1 - 2.4e-06 27.8 0.0 6.9e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 Outer mitochondrial membrane transport complex protein GST_N_3 PF13417.6 EGC28358.1 - 6.6e-05 23.2 0.0 0.00032 21.0 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC28358.1 - 0.00012 22.2 0.1 0.00049 20.2 0.0 2.0 1 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC28358.1 - 0.00018 21.5 0.0 0.00038 20.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC28358.1 - 0.019 15.3 0.0 0.076 13.3 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC28358.1 - 0.038 14.2 0.0 0.098 12.9 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.6 EGC28359.1 - 2.8e-08 34.0 8.5 3.9e-08 33.5 8.5 1.2 1 0 0 1 1 1 1 Ring finger domain PHD PF00628.29 EGC28359.1 - 0.00072 19.4 8.3 0.0012 18.7 8.3 1.4 1 0 0 1 1 1 1 PHD-finger Prok-RING_1 PF14446.6 EGC28359.1 - 0.0024 17.8 5.9 0.0054 16.6 2.7 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3HC4_3 PF13920.6 EGC28359.1 - 0.0039 17.0 5.5 0.0055 16.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.22 EGC28359.1 - 0.0053 16.6 2.4 0.0053 16.6 2.4 1.7 1 1 1 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-ANAPC11 PF12861.7 EGC28359.1 - 0.012 15.6 7.6 0.026 14.6 7.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC28359.1 - 0.014 15.0 7.8 0.023 14.3 7.8 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type C1_2 PF03107.16 EGC28359.1 - 0.015 15.6 4.0 0.05 13.9 1.4 2.2 2 0 0 2 2 2 0 C1 domain Zf_RING PF16744.5 EGC28359.1 - 0.02 15.0 8.8 0.1 12.7 8.8 1.9 1 1 0 1 1 1 0 KIAA1045 RING finger zf-Sec23_Sec24 PF04810.15 EGC28359.1 - 0.093 12.8 8.4 7.1 6.8 0.1 3.1 2 1 1 3 3 3 0 Sec23/Sec24 zinc finger zf-C3HC4 PF00097.25 EGC28359.1 - 0.14 12.1 6.5 0.29 11.0 6.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC28359.1 - 0.35 11.2 11.4 3 8.2 11.4 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-MIZ PF02891.20 EGC28359.1 - 0.81 9.5 11.2 0.31 10.8 1.6 2.8 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger PHD_4 PF16866.5 EGC28359.1 - 1.1 9.4 12.5 11 6.2 12.7 2.3 1 1 1 2 2 2 0 PHD-finger FANCL_C PF11793.8 EGC28359.1 - 1.9 8.7 8.8 5.3 7.3 8.8 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EGC28359.1 - 2.6 7.9 11.4 0.19 11.5 6.6 1.6 2 0 0 2 2 2 0 RING-like zinc finger zf-4CXXC_R1 PF10497.9 EGC28359.1 - 2.6 8.3 8.0 17 5.7 7.9 2.2 1 1 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 RecR PF02132.15 EGC28359.1 - 6.7 6.4 10.6 3 7.5 1.3 2.8 2 1 0 2 2 2 0 RecR protein Ank_2 PF12796.7 EGC28360.1 - 2e-29 102.0 0.3 3.6e-11 43.5 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC28360.1 - 3.8e-27 94.3 1.9 2.3e-12 47.2 0.1 4.7 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC28360.1 - 5e-25 86.8 0.4 3.4e-05 24.1 0.1 5.4 5 0 0 5 5 5 4 Ankyrin repeat Ank_3 PF13606.6 EGC28360.1 - 3.1e-24 82.4 1.1 4e-05 23.7 0.1 5.6 7 0 0 7 7 7 4 Ankyrin repeat Ank_5 PF13857.6 EGC28360.1 - 8.4e-19 67.4 0.1 5.9e-06 26.5 0.0 4.7 2 2 2 4 4 4 4 Ankyrin repeats (many copies) PH PF00169.29 EGC28360.1 - 8e-09 36.0 0.5 3.5e-07 30.7 0.1 2.7 2 0 0 2 2 2 1 PH domain Orf78 PF06024.12 EGC28362.1 - 0.01 16.1 2.0 0.01 16.1 2.0 3.3 3 1 0 3 3 3 0 Orf78 (ac78) Toxin_11 PF07473.11 EGC28363.1 - 8 6.7 12.6 0.44 10.7 0.4 4.2 3 0 0 3 3 3 0 Spasmodic peptide gm9a; conotoxin from Conus species NAD_binding_6 PF08030.12 EGC28364.1 - 2.2e-25 89.6 0.0 2.2e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.12 EGC28364.1 - 4.4e-25 87.9 0.1 1e-24 86.7 0.1 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.19 EGC28364.1 - 2.8e-21 75.9 9.7 5.2e-21 75.0 9.7 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_7 PF13499.6 EGC28364.1 - 9.3e-09 35.6 3.8 2.4e-08 34.3 3.8 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC28364.1 - 1.8e-08 33.6 8.9 5.5e-05 22.8 2.4 3.6 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGC28364.1 - 3.2e-08 32.5 5.1 2.2e-05 23.6 2.6 2.8 2 0 0 2 2 2 2 EF hand EF-hand_5 PF13202.6 EGC28364.1 - 9e-07 28.1 4.0 1.6e-05 24.2 2.2 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.6 EGC28364.1 - 0.00034 20.4 4.4 0.0091 15.8 2.5 2.5 1 1 1 2 2 2 2 EF-hand domain pair FAD_binding_6 PF00970.24 EGC28364.1 - 0.03 14.7 0.0 0.076 13.4 0.0 1.7 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGC28364.1 - 0.056 14.1 0.3 0.65 10.7 0.0 2.6 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain Peptidase_S28 PF05577.12 EGC28366.1 - 5.1e-74 249.6 4.0 5.1e-74 249.6 4.0 1.3 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGC28366.1 - 1.6e-08 34.5 0.0 2.8e-08 33.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC28366.1 - 0.005 16.1 0.0 0.0069 15.7 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF3246 PF11596.8 EGC28366.1 - 0.73 9.2 6.5 1.1 8.6 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) RWD PF05773.22 EGC28367.1 - 3.8e-20 72.3 9.7 5.4e-19 68.6 9.7 2.4 1 1 0 1 1 1 1 RWD domain IBR PF01485.21 EGC28367.1 - 7e-14 51.8 54.7 5.4e-08 32.9 4.8 5.3 3 1 2 5 5 5 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGC28367.1 - 0.017 15.0 8.8 0.017 15.0 8.8 5.0 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PA26 PF04636.13 EGC28368.1 - 0.21 10.5 18.8 0.32 9.9 13.3 2.0 1 1 1 2 2 2 0 PA26 p53-induced protein (sestrin) Colicin_immun PF09204.10 EGC28368.1 - 2.2 8.9 9.5 0.23 12.0 4.5 2.0 2 1 0 2 2 2 0 Bacterial self-protective colicin-like immunity TMEM144 PF07857.12 EGC28368.1 - 3.1 6.7 4.3 1.8 7.5 0.2 2.0 1 1 1 2 2 2 0 Transmembrane family, TMEM144 of transporters LMBR1 PF04791.16 EGC28368.1 - 3.4 6.5 10.2 4.5 6.1 10.2 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Trypan_PARP PF05887.11 EGC28368.1 - 6 6.8 21.4 1.4 8.9 0.2 2.6 3 0 0 3 3 3 0 Procyclic acidic repetitive protein (PARP) UPF0160 PF03690.13 EGC28369.1 - 4.3e-133 443.9 0.0 4.8e-133 443.7 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RRF PF01765.19 EGC28370.1 - 4e-46 156.9 1.1 5.4e-46 156.5 1.1 1.2 1 0 0 1 1 1 1 Ribosome recycling factor YtxH PF12732.7 EGC28370.1 - 0.16 12.5 1.4 0.31 11.6 1.4 1.5 1 0 0 1 1 1 0 YtxH-like protein PUCC PF03209.15 EGC28371.1 - 0.00029 20.0 4.9 0.00035 19.7 4.9 1.1 1 0 0 1 1 1 1 PUCC protein CbtA PF09490.10 EGC28371.1 - 0.02 14.7 2.6 2.6 7.7 0.7 2.2 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) DUF5056 PF16479.5 EGC28371.1 - 3.3 8.0 6.0 3 8.1 2.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5056) DC_STAMP PF07782.13 EGC28372.1 - 0.037 13.9 1.7 0.067 13.0 1.0 1.6 1 1 1 2 2 2 0 DC-STAMP-like protein MRAP PF15183.6 EGC28372.1 - 0.064 13.2 0.6 0.19 11.7 0.6 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PTPA PF03095.15 EGC28373.1 - 1.6e-99 333.1 2.2 7.7e-95 317.8 0.6 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein MutS_II PF05188.17 EGC28373.1 - 0.089 13.1 0.0 13 6.1 0.0 2.3 1 1 1 2 2 2 0 MutS domain II PARP PF00644.20 EGC28377.1 - 1.7e-09 37.5 0.1 2.6e-09 37.0 0.1 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_2 PF12796.7 EGC28378.1 - 9.1e-17 61.4 0.1 9.1e-07 29.4 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC28378.1 - 1.5e-11 43.5 0.2 9.8e-05 22.5 0.1 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGC28378.1 - 2.1e-10 40.6 0.0 5.6e-08 32.9 0.0 5.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC28378.1 - 2.4e-10 40.4 0.2 0.0023 18.3 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.6 EGC28378.1 - 7.2e-09 36.0 0.1 0.00089 19.8 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.6 EGC28378.1 - 1.4e-06 28.1 8.5 2.1e-06 27.5 8.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF4808 PF16066.5 EGC28379.1 - 0.14 12.7 0.1 0.35 11.4 0.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4808) FNIP PF05725.12 EGC28380.1 - 2.1e-55 184.7 48.4 2.8e-11 43.4 3.6 9.1 2 2 7 10 10 10 10 FNIP Repeat LRR_5 PF13306.6 EGC28380.1 - 0.5 10.3 13.6 0.2 11.6 0.4 3.7 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) zf-C3HC4_3 PF13920.6 EGC28383.1 - 1.8e-07 30.9 4.3 2.9e-07 30.2 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC28383.1 - 8.9e-06 25.5 5.2 8.9e-06 25.5 5.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC28383.1 - 1.4e-05 24.9 12.0 0.00025 20.9 11.8 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC28383.1 - 8.5e-05 22.3 6.8 0.00015 21.5 6.8 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC28383.1 - 0.00017 21.5 9.6 0.00041 20.2 9.6 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGC28383.1 - 0.00025 21.3 4.1 0.00048 20.3 4.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC28383.1 - 0.00036 20.8 9.3 0.0018 18.6 9.3 2.0 1 1 0 1 1 1 1 Ring finger domain DUF2985 PF11204.8 EGC28383.1 - 0.0079 16.3 0.7 0.012 15.8 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2985) Adeno_knob PF00541.17 EGC28383.1 - 0.009 15.8 0.8 0.012 15.3 0.8 1.1 1 0 0 1 1 1 1 Adenoviral fibre protein (knob domain) zf-C3HC4_4 PF15227.6 EGC28383.1 - 0.017 15.2 12.2 0.02 15.0 5.7 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC28383.1 - 0.025 14.5 3.2 0.049 13.5 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGC28383.1 - 0.059 13.4 12.2 0.61 10.1 8.7 3.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_10 PF16685.5 EGC28383.1 - 0.095 12.9 2.9 0.18 11.9 2.9 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC28383.1 - 0.13 12.1 7.5 0.25 11.2 7.5 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain OAD_gamma PF04277.13 EGC28383.1 - 0.14 12.8 0.6 0.87 10.2 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DZR PF12773.7 EGC28383.1 - 0.26 11.4 3.9 0.45 10.6 3.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Coleoptericin PF06286.11 EGC28383.1 - 0.27 11.3 2.3 0.87 9.7 2.3 1.8 1 1 0 1 1 1 0 Coleoptericin zf-CCCH PF00642.24 EGC28384.1 - 2.4e-12 46.4 21.3 4.4e-06 26.5 1.1 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGC28384.1 - 1.3e-11 45.1 9.7 0.00022 21.9 1.1 3.6 2 1 0 3 3 3 3 Torus domain zf_CCCH_4 PF18345.1 EGC28384.1 - 2.1e-11 43.5 33.6 1.8e-05 24.6 3.7 4.5 4 1 0 4 4 4 3 Zinc finger domain zf-CCCH_4 PF18044.1 EGC28384.1 - 7e-11 41.7 30.8 1.2e-06 28.1 3.0 4.3 4 0 0 4 4 4 3 CCCH-type zinc finger zf-RING_2 PF13639.6 EGC28384.1 - 5.6e-09 36.2 4.0 5.6e-09 36.2 4.0 3.1 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC28384.1 - 2.1e-06 27.5 2.5 2.1e-06 27.5 2.5 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC28384.1 - 5.1e-06 26.4 3.3 5.1e-06 26.4 3.3 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC28384.1 - 0.00041 20.3 3.5 0.00041 20.3 3.5 2.6 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC28384.1 - 0.0016 18.3 0.9 0.0016 18.3 0.9 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_2 PF14608.6 EGC28384.1 - 0.0021 18.5 32.8 0.048 14.1 7.6 4.2 4 0 0 4 4 4 3 RNA-binding, Nab2-type zinc finger FANCL_C PF11793.8 EGC28384.1 - 0.0054 16.9 3.3 0.025 14.7 3.3 2.2 1 0 0 1 1 1 1 FANCL C-terminal domain zf-CCCH_3 PF15663.5 EGC28384.1 - 0.0085 16.3 9.3 2.2 8.5 0.0 3.6 3 1 0 3 3 3 2 Zinc-finger containing family zf-RING_11 PF17123.5 EGC28384.1 - 0.011 15.5 5.0 0.011 15.5 5.0 2.6 2 0 0 2 2 2 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC28384.1 - 0.018 15.2 2.6 0.018 15.2 2.6 3.3 2 2 1 3 3 3 0 zinc finger of C3HC4-type, RING BAG PF02179.16 EGC28385.1 - 2.4e-08 34.3 8.0 0.00052 20.4 6.6 2.6 2 0 0 2 2 2 2 BAG domain AF-4 PF05110.13 EGC28385.1 - 0.0026 16.0 29.8 0.0035 15.5 29.8 1.3 1 0 0 1 1 1 1 AF-4 proto-oncoprotein DUF5408 PF17402.2 EGC28385.1 - 0.12 12.3 3.0 0.14 12.1 0.2 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5408) LOH1CR12 PF10158.9 EGC28385.1 - 1.9 8.5 8.4 0.069 13.2 1.4 2.1 2 1 1 3 3 3 0 Tumour suppressor protein Myb_DNA-binding PF00249.31 EGC28386.1 - 8.7e-34 115.5 14.4 4.9e-16 58.7 1.4 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC28386.1 - 3.7e-31 107.2 5.9 6e-15 55.2 0.4 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGC28386.1 - 0.00075 19.8 1.5 0.00075 19.8 1.5 4.1 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGC28386.1 - 0.00094 19.3 1.4 0.87 9.8 0.1 3.0 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 SLIDE PF09111.10 EGC28386.1 - 0.015 15.3 12.4 0.25 11.4 0.0 4.3 4 2 1 5 5 5 0 SLIDE Myb_DNA-bind_7 PF15963.5 EGC28386.1 - 0.069 13.1 1.1 3 7.8 0.2 3.0 2 0 0 2 2 2 0 Myb DNA-binding like Atg29_N PF18388.1 EGC28386.1 - 0.23 11.3 11.3 1.1 9.1 0.7 3.4 3 0 0 3 3 3 0 Atg29 N-terminal domain MADF_DNA_bdg PF10545.9 EGC28386.1 - 1.5 9.2 21.1 2.8 8.3 0.1 5.1 4 2 2 6 6 6 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 EGC28386.1 - 1.6 8.8 11.2 11 6.2 1.3 4.1 2 2 0 3 3 3 0 Myb/SANT-like DNA-binding domain NBD_C PF17042.5 EGC28387.1 - 0.0048 17.4 4.1 0.02 15.4 0.7 2.3 2 1 0 2 2 2 1 Nucleotide-binding C-terminal domain RL10P_insert PF17777.1 EGC28387.1 - 0.0068 16.4 0.9 0.023 14.7 0.0 2.2 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Pyr_redox PF00070.27 EGC28387.1 - 0.59 10.7 8.4 5.7 7.6 0.7 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase PIN PF01850.21 EGC28387.1 - 0.62 10.6 9.2 0.13 12.8 5.0 2.0 1 1 1 2 2 2 0 PIN domain SpecificRecomb PF10136.9 EGC28387.1 - 1.9 6.7 5.2 2.3 6.4 5.2 1.1 1 0 0 1 1 1 0 Site-specific recombinase FAM76 PF16046.5 EGC28388.1 - 0.048 13.0 0.4 0.09 12.1 0.4 1.4 1 0 0 1 1 1 0 FAM76 protein FAD-SLDH PF12318.8 EGC28390.1 - 0.094 12.8 6.0 0.12 12.5 6.0 1.3 1 0 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase SLATT_6 PF18169.1 EGC28390.1 - 0.14 11.8 6.8 0.22 11.1 6.8 1.4 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain 6 MRP-S32 PF10210.9 EGC28390.1 - 0.19 12.3 11.3 0.27 11.8 11.3 1.2 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 LptF_LptG PF03739.14 EGC28390.1 - 0.23 10.3 8.9 0.28 10.0 8.9 1.1 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Exonuc_VII_L PF02601.15 EGC28390.1 - 0.66 9.5 16.3 0.77 9.3 16.3 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit vATP-synt_E PF01991.18 EGC28390.1 - 1.8 7.9 17.8 2.4 7.5 17.8 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit OTU PF02338.19 EGC28391.1 - 1.7e-09 38.2 0.1 2.2e-09 37.9 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease OTU PF02338.19 EGC28392.1 - 1.2e-09 38.8 0.1 2.3e-09 37.8 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 EGC28392.1 - 0.34 10.9 16.4 0.48 10.4 16.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGC28392.1 - 1.4 7.6 12.0 1.9 7.1 12.0 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup OTU PF02338.19 EGC28395.1 - 1.5e-11 44.9 0.0 2.6e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease Ndc1_Nup PF09531.10 EGC28395.1 - 0.74 8.4 11.0 0.81 8.3 11.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup EF-hand_1 PF00036.32 EGC28396.1 - 5.8e-17 59.9 7.0 9.6e-05 21.7 0.5 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGC28396.1 - 5.6e-15 53.9 8.2 0.00051 19.8 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGC28396.1 - 6.6e-14 52.1 5.8 2.9e-08 34.0 0.5 2.5 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC28396.1 - 2.3e-06 26.8 4.8 0.033 13.7 0.2 4.3 4 0 0 4 4 4 2 EF hand SPARC_Ca_bdg PF10591.9 EGC28396.1 - 3.9e-06 27.1 1.6 0.0013 19.1 0.1 2.6 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGC28396.1 - 0.00021 21.0 5.4 0.11 12.4 0.4 3.6 3 1 0 3 3 3 2 EF-hand domain pair Caleosin PF05042.13 EGC28396.1 - 0.00029 20.8 2.1 0.44 10.5 0.1 3.2 2 2 1 3 3 3 2 Caleosin related protein EF-hand_13 PF17958.1 EGC28396.1 - 0.017 14.9 0.4 30 4.5 0.0 3.4 3 1 1 4 4 4 0 EF-hand domain MSA-2c PF12238.8 EGC28396.1 - 0.02 14.9 2.2 0.022 14.8 1.5 1.5 1 1 0 1 1 1 0 Merozoite surface antigen 2c Mnd1 PF03962.15 EGC28396.1 - 0.067 13.5 1.3 2.8 8.3 0.3 2.6 2 0 0 2 2 2 0 Mnd1 HTH domain VbhA PF18495.1 EGC28396.1 - 0.07 13.0 0.3 0.55 10.1 0.1 2.4 3 0 0 3 3 3 0 Antitoxin VbhA DUF5638 PF18688.1 EGC28396.1 - 0.78 10.1 6.2 5.9 7.2 0.0 3.1 1 1 1 3 3 3 0 Family of unknown function (DUF5638) Dimer_Tnp_hAT PF05699.14 EGC28397.1 - 1.5e-16 59.9 0.5 2e-16 59.6 0.5 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4300 PF14133.6 EGC28397.1 - 0.036 13.8 0.3 0.041 13.6 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) LepB_N PF18640.1 EGC28397.1 - 0.048 13.3 0.1 0.049 13.2 0.1 1.1 1 0 0 1 1 1 0 LepB N-terminal domain GP24_25 PF17388.2 EGC28400.1 - 0.12 12.4 1.0 0.28 11.2 0.2 2.1 2 0 0 2 2 2 0 Tail assembly gene products 24 & 25 DUF4710 PF15828.5 EGC28400.1 - 2.3 8.4 6.2 0.7 10.1 0.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4710) KIP1 PF07765.12 EGC28400.1 - 7.2 6.8 9.0 0.44 10.7 1.0 3.0 3 0 0 3 3 3 0 KIP1-like protein DUF1084 PF06454.11 EGC28402.1 - 4.4e-16 59.1 19.6 5.8e-16 58.7 19.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Neur_chan_memb PF02932.16 EGC28402.1 - 0.067 13.2 0.2 0.067 13.2 0.2 2.1 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4481 PF14800.6 EGC28402.1 - 1.7 8.0 10.5 2 7.8 2.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) Oxysterol_BP PF01237.18 EGC28403.1 - 1.7e-54 185.1 9.5 8.3e-52 176.2 9.5 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein DUF2362 PF10154.9 EGC28404.1 - 0.016 14.2 13.4 0.019 14.0 13.4 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) Macoilin PF09726.9 EGC28404.1 - 4.7 5.6 15.7 7.1 5.1 15.7 1.3 1 0 0 1 1 1 0 Macoilin family Cytochrom_B562 PF07361.11 EGC28405.1 - 0.012 16.2 2.2 0.3 11.7 0.2 2.0 1 1 1 2 2 2 0 Cytochrome b562 Phage_TTP_1 PF04630.12 EGC28405.1 - 0.051 12.9 0.2 0.056 12.7 0.2 1.1 1 0 0 1 1 1 0 Phage tail tube protein CotJB PF12652.7 EGC28405.1 - 0.098 12.9 3.4 2.5 8.4 0.3 2.1 1 1 1 2 2 2 0 CotJB protein Pkinase PF00069.25 EGC28406.1 - 6.2e-45 153.6 5.1 2.7e-32 112.2 0.6 4.1 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28406.1 - 5.8e-30 104.4 0.0 7.8e-14 51.6 0.1 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase BUD22 PF09073.10 EGC28406.1 - 0.00077 18.9 25.3 0.00077 18.9 25.3 2.5 2 0 0 2 2 2 1 BUD22 Nop14 PF04147.12 EGC28406.1 - 0.27 9.4 48.9 0.0031 15.8 29.9 2.4 2 0 0 2 2 2 0 Nop14-like family CDC45 PF02724.14 EGC28406.1 - 0.7 8.1 40.7 0.1 10.9 23.9 2.3 2 0 0 2 2 2 0 CDC45-like protein SDA1 PF05285.12 EGC28406.1 - 2 7.8 49.2 0.057 12.8 30.7 2.4 2 0 0 2 2 2 0 SDA1 LAP1C PF05609.12 EGC28406.1 - 2.2 7.3 39.4 2.2 7.3 18.8 2.2 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) RRM_2 PF04059.12 EGC28407.1 - 1.7e-25 89.0 0.4 1.9e-25 88.9 0.4 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_1 PF00076.22 EGC28407.1 - 0.0026 17.5 0.0 0.0034 17.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 EGC28407.1 - 0.0041 17.2 0.1 0.0053 16.8 0.1 1.1 1 0 0 1 1 1 1 Smg-4/UPF3 family LRR_8 PF13855.6 EGC28408.1 - 3.4e-20 71.6 24.7 4.1e-08 32.9 6.8 4.2 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGC28408.1 - 4.7e-19 68.2 30.6 3.2e-06 27.4 10.3 5.1 1 1 5 6 6 6 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC28408.1 - 2.5e-07 30.3 20.8 1.5 9.7 0.4 7.6 5 3 0 5 5 5 4 Leucine Rich Repeat LRR_6 PF13516.6 EGC28408.1 - 0.00035 20.4 23.2 1.1 9.5 0.1 6.9 7 0 0 7 7 7 3 Leucine Rich repeat DUF3439 PF11921.8 EGC28408.1 - 0.041 13.8 1.6 0.072 13.1 1.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NOG1 PF06858.14 EGC28408.1 - 0.066 13.0 0.0 0.19 11.6 0.0 1.7 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FNIP PF05725.12 EGC28409.1 - 8e-96 314.0 47.0 1.1e-10 41.4 0.1 11.6 4 2 5 13 13 13 13 FNIP Repeat LRR_5 PF13306.6 EGC28409.1 - 1.8e-09 37.6 4.2 0.00032 20.6 0.0 5.0 2 2 1 4 4 4 4 BspA type Leucine rich repeat region (6 copies) DUF3823_C PF18003.1 EGC28410.1 - 0.015 16.0 0.6 0.017 15.8 0.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF3823_C) HNF-1A_C PF04813.12 EGC28412.1 - 0.11 13.3 1.7 0.17 12.7 1.7 1.4 1 1 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), alpha isoform C terminus DUF4681 PF15732.5 EGC28413.1 - 0.002 18.4 0.3 0.0032 17.7 0.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4681) zf-C2HE PF16278.5 EGC28413.1 - 0.075 13.5 0.7 0.091 13.2 0.3 1.5 1 1 0 1 1 1 0 C2HE / C2H2 / C2HC zinc-binding finger Bromodomain PF00439.25 EGC28414.1 - 6.5e-09 35.7 0.4 6.5e-09 35.7 0.4 2.0 3 0 0 3 3 3 1 Bromodomain Med11 PF10280.9 EGC28414.1 - 0.024 15.1 1.1 0.031 14.7 1.1 1.3 1 0 0 1 1 1 0 Mediator complex protein SesA PF17107.5 EGC28414.1 - 0.067 13.4 0.4 4 7.6 0.1 2.2 1 1 1 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases Spuma_A9PTase PF03539.14 EGC28414.1 - 0.074 13.2 0.5 0.15 12.2 0.2 1.6 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) ALMT PF11744.8 EGC28414.1 - 0.31 9.8 2.9 0.38 9.5 2.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Plk4_PB2 PF18409.1 EGC28414.1 - 1.4 9.6 5.0 2.5 8.8 1.1 2.4 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 DUF4834 PF16118.5 EGC28414.1 - 3.4 8.7 5.4 85 4.2 5.4 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Ammonium_transp PF00909.21 EGC28420.1 - 3.6e-112 375.0 24.6 4.1e-112 374.8 24.6 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Zip PF02535.22 EGC28421.1 - 0.022 14.0 0.2 0.029 13.6 0.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2076 PF09849.9 EGC28421.1 - 0.054 13.5 5.7 0.056 13.5 5.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Presenilin PF01080.17 EGC28421.1 - 7.9 5.1 5.3 8.9 5.0 5.3 1.1 1 0 0 1 1 1 0 Presenilin Methyltransf_4 PF02390.17 EGC28423.1 - 1e-23 83.7 2.7 1e-23 83.7 2.7 2.3 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.6 EGC28423.1 - 0.00065 19.5 0.0 0.0018 18.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC28423.1 - 0.0012 19.5 0.0 0.0028 18.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC28423.1 - 0.0023 17.8 0.0 0.0053 16.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC28423.1 - 0.045 14.5 2.8 0.045 14.5 2.8 3.2 3 1 0 3 3 3 0 Methyltransferase domain HD_3 PF13023.6 EGC28423.1 - 0.12 12.3 0.2 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 HD domain Methyltransf_11 PF08241.12 EGC28423.1 - 0.16 12.6 0.0 0.41 11.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain AMP-binding PF00501.28 EGC28424.1 - 6.2e-78 262.3 0.0 7.2e-78 262.1 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC28424.1 - 1.7e-12 48.2 0.0 4.3e-12 46.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TraI_2_C PF07515.11 EGC28424.1 - 0.046 13.7 0.1 8.5 6.3 0.0 2.6 2 0 0 2 2 2 0 Putative conjugal transfer nickase/helicase TraI C-term TruB_N PF01509.18 EGC28425.1 - 1.3e-40 139.2 0.2 2.2e-40 138.5 0.2 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) TruB_C_2 PF16198.5 EGC28425.1 - 0.013 15.6 0.0 0.023 14.8 0.0 1.4 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain Clat_adaptor_s PF01217.20 EGC28426.1 - 9.3e-21 74.2 3.5 1.2e-20 73.8 3.5 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.22 EGC28427.1 - 3.1e-60 202.5 0.1 3.5e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28427.1 - 6.8e-34 116.7 0.0 5e-33 113.9 0.0 1.9 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC28427.1 - 6.3e-11 42.0 0.1 7.9e-11 41.7 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC28427.1 - 6.5e-05 22.4 0.0 8.4e-05 22.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC28427.1 - 0.00018 21.4 0.1 0.12 12.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC28427.1 - 0.00047 20.2 0.0 0.0007 19.7 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC28427.1 - 0.0014 18.2 0.0 0.003 17.1 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.6 EGC28427.1 - 0.022 15.1 0.1 0.041 14.3 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain NBD_C PF17042.5 EGC28427.1 - 0.15 12.6 0.1 0.22 12.0 0.1 1.2 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain SAYSvFN PF10260.9 EGC28428.1 - 4.1e-25 87.5 0.7 5.9e-25 87.0 0.7 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) FUSC_2 PF13515.6 EGC28428.1 - 0.046 13.8 0.4 0.064 13.4 0.4 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Aminotran_5 PF00266.19 EGC28429.1 - 4.3e-32 111.5 0.0 8e-32 110.6 0.0 1.5 1 1 0 1 1 1 1 Aminotransferase class-V MOSC PF03473.17 EGC28429.1 - 4.7e-25 88.1 0.0 8.7e-25 87.2 0.0 1.4 1 0 0 1 1 1 1 MOSC domain MOSC_N PF03476.16 EGC28429.1 - 6.8e-22 77.6 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain Zip PF02535.22 EGC28429.1 - 0.13 11.5 0.7 0.19 10.9 0.7 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PCYCGC PF13798.6 EGC28429.1 - 2.1 8.2 4.1 0.62 9.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function with PCYCGC motif DUF4492 PF14899.6 EGC28429.1 - 2.2 8.3 4.1 1.1 9.2 1.6 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4492) Autotransporter PF03797.19 EGC28430.1 - 0.26 10.9 4.1 5.6 6.5 0.2 2.5 2 1 0 2 2 2 0 Autotransporter beta-domain Pkinase PF00069.25 EGC28431.1 - 9.7e-13 48.1 0.0 1e-12 48.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28431.1 - 1.8e-10 40.6 0.0 1.9e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC28431.1 - 1.2e-05 24.8 0.0 1.3e-05 24.7 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC28431.1 - 0.00022 20.2 0.0 0.00022 20.2 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGC28431.1 - 0.0029 17.2 0.1 0.0034 17.0 0.1 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.20 EGC28431.1 - 0.083 12.5 0.3 0.09 12.4 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase FNIP PF05725.12 EGC28432.1 - 2.2e-35 120.5 53.0 5.1e-11 42.6 2.2 8.3 4 2 4 9 9 9 8 FNIP Repeat Dapper PF15268.6 EGC28434.1 - 0.28 10.0 17.4 0.32 9.8 17.4 1.0 1 0 0 1 1 1 0 Dapper OTU PF02338.19 EGC28436.1 - 4.6e-09 36.8 0.1 5.8e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3489 PF11994.8 EGC28436.1 - 0.072 13.2 0.2 0.13 12.4 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3489) U-box PF04564.15 EGC28436.1 - 0.18 12.0 0.2 8.6 6.6 0.0 2.3 2 0 0 2 2 2 0 U-box domain EF-hand_7 PF13499.6 EGC28438.1 - 2.6e-27 95.1 8.6 3.9e-10 40.0 0.3 2.8 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGC28438.1 - 7.4e-24 81.5 4.7 4.9e-05 22.6 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGC28438.1 - 3e-20 70.3 0.5 0.00047 19.9 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC28438.1 - 8.6e-15 53.5 1.4 1.8e-05 24.0 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGC28438.1 - 2e-14 53.2 1.9 7.1e-06 25.8 0.0 4.1 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC28438.1 - 1.6e-08 34.8 2.0 0.0026 18.0 0.1 2.3 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGC28438.1 - 0.00068 19.8 2.3 0.5 10.6 0.2 3.4 3 1 1 4 4 4 1 Dockerin type I domain EF-hand_9 PF14658.6 EGC28438.1 - 0.0032 17.8 0.1 0.28 11.6 0.1 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.6 EGC28438.1 - 0.017 15.0 1.6 0.19 11.6 0.1 2.7 2 1 1 3 3 3 0 EF hand DUF5638 PF18688.1 EGC28438.1 - 0.028 14.7 6.3 0.43 10.9 0.4 3.0 1 1 1 3 3 3 0 Family of unknown function (DUF5638) Trehalase_Ca-bi PF07492.11 EGC28438.1 - 0.12 12.1 4.0 7.7 6.3 0.1 3.8 4 0 0 4 4 4 0 Neutral trehalase Ca2+ binding domain Sugar_tr PF00083.24 EGC28439.1 - 7.6e-40 137.1 24.0 1.7e-21 76.6 8.7 2.1 1 1 1 2 2 2 2 Sugar (and other) transporter MFS_1 PF07690.16 EGC28439.1 - 2.3e-35 122.2 42.8 7.7e-30 104.0 26.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGC28439.1 - 0.0014 17.3 3.6 0.0014 17.3 3.6 3.2 2 1 1 3 3 3 2 MFS/sugar transport protein UPF0154 PF03672.13 EGC28439.1 - 3 7.9 6.7 2.7 8.1 0.0 3.6 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Peptidase_C1 PF00112.23 EGC28440.1 - 4.5e-60 203.4 4.4 5.3e-60 203.2 4.4 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGC28440.1 - 5.6e-07 28.7 1.4 0.0023 16.8 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Sod_Cu PF00080.20 EGC28441.1 - 4.6e-36 124.1 0.2 1.4e-26 93.3 2.1 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) EIF_2_alpha PF07541.12 EGC28442.1 - 7.6e-34 116.3 0.0 1.9e-33 115.0 0.0 1.7 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit Porin_3 PF01459.22 EGC28442.1 - 1.7e-18 67.1 9.3 2.2e-18 66.7 9.3 1.1 1 0 0 1 1 1 1 Eukaryotic porin S1 PF00575.23 EGC28442.1 - 5.6e-15 55.5 1.5 1.6e-14 54.0 1.5 1.8 1 0 0 1 1 1 1 S1 RNA binding domain Tub_N PF16322.5 EGC28442.1 - 0.016 15.7 0.4 0.024 15.0 0.4 1.4 1 0 0 1 1 1 0 Tubby N-terminal GlcNAc-1_reg PF18440.1 EGC28442.1 - 0.14 12.4 0.5 5.8 7.2 0.1 3.2 2 1 1 3 3 3 0 Putative GlcNAc-1 phosphotransferase regulatory domain Porin_7 PF16956.5 EGC28442.1 - 0.27 10.8 7.0 0.17 11.5 4.8 1.7 1 1 0 2 2 2 0 Putative general bacterial porin MBG PF17883.1 EGC28442.1 - 3.3 8.4 8.6 0.89 10.2 2.6 2.8 2 1 0 2 2 2 0 MBG domain Nucleo_P87 PF07267.11 EGC28444.1 - 0.00072 18.6 11.6 0.00083 18.4 11.6 1.1 1 0 0 1 1 1 1 Nucleopolyhedrovirus capsid protein P87 Suf PF05843.14 EGC28444.1 - 0.0029 17.7 16.2 0.0049 16.9 16.2 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) Hid1 PF12722.7 EGC28444.1 - 0.0051 15.0 15.3 0.0065 14.7 15.3 1.0 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Kei1 PF08552.11 EGC28444.1 - 0.0087 16.0 1.1 0.0087 16.0 1.1 1.9 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 Hamartin PF04388.12 EGC28444.1 - 0.027 13.1 14.3 0.035 12.8 14.3 1.1 1 0 0 1 1 1 0 Hamartin protein SRP-alpha_N PF04086.13 EGC28444.1 - 0.04 13.8 11.9 0.052 13.5 11.9 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal MID_MedPIWI PF18296.1 EGC28444.1 - 0.12 12.2 12.9 0.16 11.7 12.9 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Senescence_reg PF04520.13 EGC28444.1 - 0.17 12.7 9.6 0.25 12.2 9.6 1.1 1 0 0 1 1 1 0 Senescence regulator PAT1 PF09770.9 EGC28444.1 - 0.2 9.9 26.7 0.25 9.5 26.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RR_TM4-6 PF06459.12 EGC28444.1 - 0.2 11.4 14.1 0.29 10.9 14.1 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 TFIIA PF03153.13 EGC28444.1 - 0.21 11.5 35.1 0.27 11.2 35.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC45 PF02724.14 EGC28444.1 - 0.25 9.6 7.0 0.35 9.1 7.0 1.2 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 EGC28444.1 - 0.32 11.3 12.0 0.41 10.9 12.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family LAP1C PF05609.12 EGC28444.1 - 0.36 9.9 13.4 0.047 12.8 9.7 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Pkinase_fungal PF17667.1 EGC28444.1 - 0.37 9.5 3.1 0.47 9.2 3.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase CCSAP PF15748.5 EGC28444.1 - 0.51 10.5 21.8 0.7 10.0 21.8 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Endostatin PF06482.11 EGC28444.1 - 0.79 9.1 14.0 0.97 8.8 14.0 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin Mitofilin PF09731.9 EGC28444.1 - 1.9 7.2 18.6 3.3 6.4 18.6 1.3 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SPX PF03105.19 EGC28444.1 - 3.8 7.3 21.2 5.5 6.8 21.2 1.1 1 0 0 1 1 1 0 SPX domain Band_3_cyto PF07565.13 EGC28444.1 - 4.6 7.0 9.9 6.9 6.4 9.9 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 EGC28444.1 - 7.9 5.4 15.7 10 5.0 15.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Ribonuc_P_40 PF08584.11 EGC28444.1 - 8.5 5.6 12.8 12 5.1 12.8 1.1 1 0 0 1 1 1 0 Ribonuclease P 40kDa (Rpp40) subunit Fer4_14 PF13394.6 EGC28446.1 - 0.014 15.5 0.1 0.015 15.4 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S single cluster domain FNIP PF05725.12 EGC28447.1 - 1.5e-191 620.4 80.5 1.8e-15 56.8 0.1 12.1 3 2 13 17 17 17 17 FNIP Repeat Phage_min_tail PF05939.13 EGC28447.1 - 2.3e-08 34.4 0.0 54 4.2 0.0 9.4 3 2 7 11 11 11 0 Phage minor tail protein MCM_OB PF17207.3 EGC28447.1 - 1e-06 28.6 0.2 26 4.7 0.0 7.8 2 2 7 11 11 11 1 MCM OB domain Cdh1_DBD_1 PF18196.1 EGC28447.1 - 0.016 15.5 2.8 1.1e+02 3.2 0.0 7.7 5 5 11 16 16 16 0 Chromodomain helicase DNA-binding domain 1 LRR_1 PF00560.33 EGC28447.1 - 0.2 12.3 8.8 1.5e+02 3.6 0.0 7.8 5 4 3 8 8 8 0 Leucine Rich Repeat 2-Hacid_dh_C PF02826.19 EGC28448.1 - 6.8e-58 195.0 0.0 1.2e-57 194.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC28448.1 - 4e-21 75.1 0.0 5.8e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC28448.1 - 0.00044 20.4 0.0 0.0011 19.2 0.0 1.6 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase PI3_PI4_kinase PF00454.27 EGC28449.1 - 2.6e-34 119.2 0.2 1.1e-31 110.5 0.2 2.9 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC28449.1 - 0.0016 17.9 0.1 0.004 16.6 0.1 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.25 EGC28450.1 - 2.1e-21 76.5 28.5 1.8e-15 57.0 5.3 5.1 3 1 2 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28450.1 - 1.5e-13 50.6 0.1 1.7e-05 24.3 0.1 3.4 2 1 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 EGC28450.1 - 0.013 14.9 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC28450.1 - 0.044 12.6 3.9 0.096 11.4 3.9 1.5 1 1 0 1 1 1 0 Fungal protein kinase DUF2971 PF11185.8 EGC28451.1 - 0.51 11.5 5.3 0.71 11.1 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) FANCI_HD1 PF14679.6 EGC28452.1 - 0.045 13.7 0.6 0.099 12.6 0.6 1.6 1 0 0 1 1 1 0 FANCI helical domain 1 SID-1_RNA_chan PF13965.6 EGC28452.1 - 0.32 9.4 1.8 0.5 8.7 1.8 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3361 PF11841.8 EGC28454.1 - 0.00087 19.2 2.9 0.00087 19.2 2.9 2.3 1 1 1 2 2 2 1 Domain of unknown function (DUF3361) AbiJ_NTD5 PF18865.1 EGC28454.1 - 0.022 14.5 0.3 0.98 9.3 0.0 3.0 2 0 0 2 2 2 0 AbiJ N-terminal domain 5 DUF3439 PF11921.8 EGC28454.1 - 5.6 7.0 8.9 10 6.1 8.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ATP_transf PF09830.9 EGC28455.1 - 8.2e-20 70.7 0.0 1.5e-19 69.9 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase DUF4922 PF16269.5 EGC28455.1 - 5.8e-05 22.9 1.3 0.0041 16.9 1.3 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4922) FNIP PF05725.12 EGC28456.1 - 1.5e-38 130.7 37.5 1.2e-09 38.2 0.3 9.4 5 4 3 8 8 8 7 FNIP Repeat SPATA6 PF14909.6 EGC28456.1 - 0.025 14.7 0.2 0.42 10.8 0.0 2.6 3 1 0 3 3 3 0 Spermatogenesis-assoc protein 6 Get5_bdg PF16843.5 EGC28456.1 - 0.027 14.0 0.3 1.4 8.5 0.0 3.0 2 0 0 2 2 2 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein SWIM PF04434.17 EGC28457.1 - 2.8e-05 23.7 0.3 5e-05 22.9 0.3 1.5 1 0 0 1 1 1 1 SWIM zinc finger RICTOR_M PF14666.6 EGC28457.1 - 0.0069 16.1 0.3 1.5 8.6 0.0 2.3 1 1 1 2 2 2 2 Rapamycin-insensitive companion of mTOR, middle domain PuR_N PF09182.10 EGC28457.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal FNIP PF05725.12 EGC28458.1 - 1.9e-57 191.2 53.3 2.8e-11 43.4 0.2 9.5 9 1 0 10 10 10 7 FNIP Repeat FNIP PF05725.12 EGC28460.1 - 3.2e-10 40.0 2.4 0.00047 20.3 0.2 3.4 1 1 0 3 3 3 3 FNIP Repeat Pex2_Pex12 PF04757.14 EGC28461.1 - 5.1e-31 108.0 9.8 1.8e-30 106.2 9.8 1.8 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.6 EGC28461.1 - 2e-08 34.4 16.4 3.2e-08 33.8 16.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC28461.1 - 5.9e-07 29.3 15.0 9.5e-07 28.6 15.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC28461.1 - 7.4e-06 25.7 16.7 1.4e-05 24.9 16.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC28461.1 - 8.5e-06 26.0 13.0 1.6e-05 25.1 13.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC28461.1 - 2.1e-05 24.2 15.9 3.8e-05 23.4 15.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC28461.1 - 0.00083 19.2 15.5 0.0014 18.4 15.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC28461.1 - 0.0032 17.4 15.9 0.0059 16.5 15.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC28461.1 - 0.013 15.5 16.0 0.033 14.2 15.0 2.1 1 1 1 2 2 2 0 RING-type zinc-finger TMEM144 PF07857.12 EGC28461.1 - 0.025 13.5 0.1 0.1 11.6 0.0 1.8 2 0 0 2 2 2 0 Transmembrane family, TMEM144 of transporters zf-C3HC4_4 PF15227.6 EGC28461.1 - 0.049 13.8 14.0 0.16 12.2 13.9 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC28461.1 - 0.43 10.7 9.8 0.83 9.7 9.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGC28461.1 - 2.2 8.2 9.8 3.9 7.4 9.8 1.3 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_2 PF12674.7 EGC28462.1 - 0.023 15.3 0.1 0.052 14.2 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF3877 PF12993.7 EGC28462.1 - 0.025 14.4 0.0 0.028 14.3 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3877) Aa_trans PF01490.18 EGC28464.1 - 3.3e-19 68.9 44.1 9e-11 41.1 38.0 2.4 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein CLIP_SPH_Scar PF18399.1 EGC28466.1 - 0.13 12.4 0.0 0.18 11.9 0.0 1.2 1 0 0 1 1 1 0 Clip-domain serine protease homolog Scarface TAF6_C PF07571.13 EGC28467.1 - 5.8e-33 113.1 0.0 1.6e-32 111.7 0.0 1.8 1 0 0 1 1 1 1 TAF6 C-terminal HEAT repeat domain TAF PF02969.17 EGC28467.1 - 8.5e-28 96.3 0.1 1.6e-27 95.5 0.1 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) TFIID-31kDa PF02291.15 EGC28467.1 - 0.0021 18.1 1.1 0.004 17.2 0.0 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGC28467.1 - 0.038 14.3 0.4 0.16 12.3 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGC28467.1 - 0.086 12.9 0.0 1.1 9.3 0.0 2.6 2 0 0 2 2 2 0 Bromodomain associated Histone PF00125.24 EGC28467.1 - 0.14 12.5 0.1 0.14 12.5 0.1 1.8 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 RNB PF00773.19 EGC28468.1 - 2.4e-67 227.6 4.5 2.8e-66 224.1 4.5 2.4 1 1 0 1 1 1 1 RNB domain CorA PF01544.18 EGC28469.1 - 5.4e-43 147.4 5.0 5.4e-43 147.4 5.0 2.3 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein RRM_1 PF00076.22 EGC28470.1 - 7.5e-19 67.3 0.1 3e-10 39.8 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC28470.1 - 0.0011 18.6 1.6 0.02 14.5 0.0 2.8 2 1 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC28470.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif Coiled PF05710.12 EGC28471.1 - 1.1e-15 58.3 14.2 1.4e-15 57.9 14.2 1.1 1 0 0 1 1 1 1 Coiled coil HEAT PF02985.22 EGC28472.1 - 2e-22 77.3 2.4 0.00014 21.8 0.0 10.0 11 0 0 11 11 9 3 HEAT repeat HEAT_EZ PF13513.6 EGC28472.1 - 2.4e-12 47.1 1.2 4.1e-06 27.2 0.0 6.4 7 0 0 7 7 6 2 HEAT-like repeat HEAT_2 PF13646.6 EGC28472.1 - 3.3e-11 43.4 0.0 0.0069 16.7 0.0 6.6 4 2 4 8 8 8 2 HEAT repeats Vac14_Fab1_bd PF12755.7 EGC28472.1 - 3.9e-09 37.0 7.3 0.017 15.7 0.3 7.6 4 3 4 9 9 9 2 Vacuolar 14 Fab1-binding region IBN_N PF03810.19 EGC28472.1 - 4.1e-09 36.2 4.1 1.4e-08 34.5 0.5 3.7 3 1 0 3 3 3 1 Importin-beta N-terminal domain Arm PF00514.23 EGC28472.1 - 1.8e-07 31.0 5.1 0.012 15.6 0.0 4.7 4 0 0 4 4 4 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.8 EGC28472.1 - 2.8e-07 30.3 5.2 0.0072 15.9 0.2 5.1 5 1 1 6 6 6 2 CLASP N terminal Cnd1 PF12717.7 EGC28472.1 - 6.8e-06 26.2 8.9 0.014 15.4 0.3 5.6 4 2 2 6 6 6 2 non-SMC mitotic condensation complex subunit 1 MMS19_N PF14500.6 EGC28472.1 - 0.00061 19.4 0.1 1.4 8.5 0.2 3.8 3 1 1 4 4 4 1 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EGC28472.1 - 0.0053 15.9 9.6 0.33 10.0 2.3 4.5 1 1 1 4 4 4 2 RNAPII transcription regulator C-terminal RepA_C PF04796.12 EGC28472.1 - 0.0083 16.2 0.0 0.022 14.8 0.0 1.7 1 0 0 1 1 1 1 Plasmid encoded RepA protein TAF6_C PF07571.13 EGC28472.1 - 0.0089 16.3 0.7 12 6.3 0.0 4.9 5 1 1 6 6 6 1 TAF6 C-terminal HEAT repeat domain RTP1_C1 PF10363.9 EGC28472.1 - 0.041 14.1 0.9 0.88 9.8 0.1 3.7 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 Sec7_N PF12783.7 EGC28472.1 - 0.33 10.8 3.9 47 3.8 0.0 4.2 6 0 0 6 6 6 0 Guanine nucleotide exchange factor in Golgi transport N-terminal UAA PF08449.11 EGC28474.1 - 2.1e-32 112.6 28.5 3.2e-32 112.0 28.5 1.3 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGC28474.1 - 4.1e-06 27.0 17.1 4.1e-06 27.0 17.1 3.0 2 1 0 2 2 2 1 EamA-like transporter family DUF1045 PF06299.12 EGC28475.1 - 0.00045 20.2 0.0 0.0006 19.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) 2_5_RNA_ligase2 PF13563.6 EGC28475.1 - 0.0029 17.5 0.0 0.027 14.4 0.0 2.1 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.16 EGC28475.1 - 0.0091 16.2 0.0 5.5 7.3 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase Dickkopf_N PF04706.12 EGC28476.1 - 2.3e-09 37.6 9.1 2.3e-09 37.6 9.1 6.9 5 1 1 6 6 6 2 Dickkopf N-terminal cysteine-rich region RGCC PF15151.6 EGC28476.1 - 0.23 11.7 2.2 0.41 10.9 2.2 1.3 1 0 0 1 1 1 0 Response gene to complement 32 protein family ENTH PF01417.20 EGC28477.1 - 0.015 15.3 0.4 0.026 14.6 0.4 1.4 1 0 0 1 1 1 0 ENTH domain RhoGEF PF00621.20 EGC28479.1 - 7.9e-37 127.2 4.9 7.9e-37 127.2 4.9 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC28479.1 - 1.3e-06 28.8 1.8 9.7e-06 26.0 0.1 2.5 2 0 0 2 2 2 1 PH domain PH_16 PF17838.1 EGC28479.1 - 0.0019 18.0 0.6 0.0087 15.9 0.6 2.1 1 1 0 1 1 1 1 PH domain KH_6 PF15985.5 EGC28480.1 - 4.3e-13 49.4 0.1 8.5e-13 48.4 0.1 1.4 1 0 0 1 1 1 1 KH domain Rrp40_N PF18311.1 EGC28480.1 - 3.7e-07 30.0 0.0 7.5e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease Rrp40 N-terminal domain ECR1_N PF14382.6 EGC28480.1 - 0.034 14.0 0.1 0.065 13.0 0.1 1.5 1 0 0 1 1 1 0 Exosome complex exonuclease RRP4 N-terminal region DHHC PF01529.20 EGC28481.1 - 1.4e-23 83.5 13.4 1.4e-23 83.5 13.4 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SAYSvFN PF10260.9 EGC28481.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.0 2 0 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DUF4820 PF16091.5 EGC28481.1 - 4.2 6.7 10.7 6.3 6.1 10.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NPR3 PF03666.13 EGC28481.1 - 4.8 5.9 16.5 6.2 5.5 16.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FYDLN_acid PF09538.10 EGC28481.1 - 7.3 7.3 17.7 3.4e+02 2.0 17.7 2.5 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Rad60-SLD PF11976.8 EGC28482.1 - 4.3e-09 36.1 0.5 1.5e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC28482.1 - 9.5e-06 25.3 0.1 5e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin family Androgen_recep PF02166.16 EGC28482.1 - 7.4 5.3 9.6 17 4.1 9.6 1.5 1 0 0 1 1 1 0 Androgen receptor DUF3438 PF11920.8 EGC28482.1 - 9.1 5.4 8.3 17 4.5 8.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) SPRY PF00622.28 EGC28483.1 - 7.1e-50 168.1 8.4 2.5e-22 79.2 0.7 3.4 3 0 0 3 3 3 3 SPRY domain PIP5K PF01504.18 EGC28484.1 - 1.5e-69 234.3 9.1 2.4e-69 233.6 9.1 1.3 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Herpes_capsid PF06112.11 EGC28486.1 - 0.011 15.8 2.7 0.011 15.8 2.7 2.1 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF4834 PF16118.5 EGC28487.1 - 2.5 9.1 17.8 9 7.3 9.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Lin-8 PF03353.15 EGC28487.1 - 9.3 5.7 15.5 11 5.4 15.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CSN8_PSD8_EIF3K PF10075.9 EGC28488.1 - 6.8e-28 97.5 0.1 9.2e-28 97.0 0.1 1.2 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family TBP PF00352.21 EGC28489.1 - 2.8e-64 213.1 0.8 6.8e-31 106.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.8 EGC28489.1 - 6.1e-05 23.1 0.0 0.11 12.6 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.6 EGC28489.1 - 0.043 13.6 0.2 0.19 11.5 0.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Ribosomal_S24e PF01282.19 EGC28490.1 - 1.2e-32 111.6 0.2 1.2e-32 111.6 0.2 1.7 1 1 1 2 2 2 1 Ribosomal protein S24e Cmc1 PF08583.10 EGC28491.1 - 1.3e-19 69.9 6.2 2e-19 69.4 6.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Yqai PF09466.10 EGC28491.1 - 0.036 14.4 0.0 0.069 13.5 0.0 1.5 1 0 0 1 1 1 0 Hypothetical protein Yqai 5_nucleotid PF05761.14 EGC28492.1 - 4.8e-146 487.3 1.7 6.8e-146 486.8 1.7 1.2 1 0 0 1 1 1 1 5' nucleotidase family mCpol PF18182.1 EGC28493.1 - 8.7 6.7 8.7 1.7 9.0 3.4 2.4 2 0 0 2 2 2 0 minimal CRISPR polymerase domain F5_F8_type_C PF00754.25 EGC28494.1 - 1e-25 90.3 2.2 1.8e-25 89.5 1.1 1.8 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC28494.1 - 1.3e-18 66.9 1.2 3.6e-18 65.5 0.4 2.1 2 0 0 2 2 2 1 H-type lectin domain Arrestin_C PF02752.22 EGC28495.1 - 2.7e-12 47.3 0.1 9.8e-11 42.2 0.0 5.2 3 3 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGC28495.1 - 6.3e-08 32.8 1.7 1e-05 25.6 0.4 3.5 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain RCC1 PF00415.18 EGC28496.1 - 1.6e-34 118.3 0.1 1.9e-10 41.2 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC28496.1 - 2.7e-26 90.7 15.2 9.6e-11 41.2 0.1 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Pkinase PF00069.25 EGC28498.1 - 1.4e-68 231.1 0.0 1.4e-68 231.1 0.0 3.1 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28498.1 - 5.2e-31 107.9 0.0 1.8e-30 106.1 0.0 1.9 1 0 0 1 1 1 1 Protein tyrosine kinase Sina PF03145.16 EGC28499.1 - 3.8e-13 49.9 1.1 6.1e-13 49.2 1.1 1.3 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGC28499.1 - 0.0006 19.6 7.8 0.0014 18.4 7.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Sigma70_ner PF04546.13 EGC28499.1 - 0.024 14.5 17.4 0.04 13.8 17.4 1.3 1 0 0 1 1 1 0 Sigma-70, non-essential region Cwf_Cwc_15 PF04889.12 EGC28499.1 - 0.036 13.8 21.9 0.093 12.4 21.9 1.7 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein C1_2 PF03107.16 EGC28499.1 - 0.046 14.1 7.9 0.046 14.1 7.9 2.2 2 0 0 2 2 2 0 C1 domain Astro_capsid_p PF12226.8 EGC28499.1 - 0.22 10.7 13.6 0.31 10.2 13.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein PPP4R2 PF09184.11 EGC28499.1 - 0.36 10.4 18.4 0.62 9.6 18.4 1.4 1 0 0 1 1 1 0 PPP4R2 zf-C2H2_11 PF16622.5 EGC28499.1 - 0.8 9.5 3.7 4 7.3 0.4 2.6 2 0 0 2 2 2 0 zinc-finger C2H2-type SGT1 PF07093.11 EGC28499.1 - 0.92 7.9 12.2 1.4 7.3 12.2 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 EGC28499.1 - 0.99 7.6 21.8 1.4 7.1 21.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGC28499.1 - 1.5 7.0 26.1 2.6 6.2 26.1 1.3 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGC28499.1 - 1.6 6.8 37.6 2.4 6.2 37.6 1.2 1 0 0 1 1 1 0 DNA polymerase phi zf-RING_5 PF14634.6 EGC28499.1 - 3.4 7.7 12.0 16 5.6 12.0 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Sporozoite_P67 PF05642.11 EGC28499.1 - 4.2 5.3 14.2 6.7 4.7 14.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RRN3 PF05327.11 EGC28499.1 - 4.4 5.7 21.3 6.1 5.3 21.3 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 CobT PF06213.12 EGC28499.1 - 5.4 6.3 22.3 7.8 5.8 22.3 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT zf-C3HC4_2 PF13923.6 EGC28499.1 - 5.9 6.8 11.6 15 5.6 11.6 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FYDLN_acid PF09538.10 EGC28499.1 - 6.4 7.5 28.8 0.98 10.1 22.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (FYDLN_acid) LSM PF01423.22 EGC28500.1 - 3.2e-15 55.6 0.4 5.4e-15 54.8 0.4 1.4 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC28500.1 - 0.00074 19.6 0.3 0.0014 18.7 0.1 1.8 1 1 1 2 2 2 1 Ataxin 2 SM domain DUF1256 PF06866.11 EGC28500.1 - 0.052 13.0 0.1 0.069 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) DEAD PF00270.29 EGC28501.1 - 2.7e-31 108.7 1.1 3.5e-31 108.3 0.4 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC28501.1 - 1.3e-24 86.7 0.0 4.2e-24 85.0 0.0 1.9 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.6 EGC28501.1 - 0.029 14.6 0.0 0.065 13.4 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain DUF1811 PF08838.10 EGC28501.1 - 0.063 13.5 0.0 0.16 12.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) CMS1 PF14617.6 EGC28501.1 - 0.13 11.5 0.9 0.25 10.6 0.1 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit DUF3439 PF11921.8 EGC28502.1 - 0.95 9.4 10.3 2.7 8.0 10.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TACC_C PF05010.14 EGC28503.1 - 0.0011 18.9 26.5 0.027 14.2 3.6 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PspB PF06667.12 EGC28503.1 - 0.097 12.7 3.4 13 6.0 0.1 3.4 3 0 0 3 3 3 0 Phage shock protein B OTU PF02338.19 EGC28504.1 - 0.00012 22.6 0.0 0.00012 22.6 0.0 3.4 2 1 0 2 2 2 1 OTU-like cysteine protease Presenilin PF01080.17 EGC28504.1 - 0.03 13.1 8.1 0.034 12.9 8.1 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC28504.1 - 0.18 11.7 40.8 0.24 11.4 40.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EGC28504.1 - 0.62 10.1 6.8 0.91 9.5 6.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.13 EGC28504.1 - 2.5 7.8 15.6 3.7 7.3 15.6 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Vac7 PF12751.7 EGC28504.1 - 4.2 6.7 8.0 5.2 6.4 8.0 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Sin_N PF04801.13 EGC28504.1 - 7.9 5.6 33.4 9.7 5.3 33.4 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region NCKAP5 PF15246.6 EGC28504.1 - 9.4 5.7 23.7 12 5.4 23.7 1.1 1 0 0 1 1 1 0 Nck-associated protein 5, Peripheral clock protein SDA1 PF05285.12 EGC28505.1 - 0.14 11.5 12.8 0.19 11.1 12.8 1.1 1 0 0 1 1 1 0 SDA1 PPP4R2 PF09184.11 EGC28505.1 - 0.22 11.1 14.2 0.28 10.7 14.2 1.1 1 0 0 1 1 1 0 PPP4R2 FAM176 PF14851.6 EGC28505.1 - 0.58 9.8 12.3 0.12 12.0 2.7 2.1 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 EGC28505.1 - 2.8 8.4 24.3 1.5 9.3 14.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pkinase PF00069.25 EGC28506.1 - 5.5e-63 212.8 0.0 1.1e-62 211.8 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28506.1 - 1.4e-46 158.9 0.0 2.9e-46 157.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC28506.1 - 0.00046 19.6 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGC28506.1 - 0.0014 17.5 0.0 0.0014 17.5 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGC28506.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4611 PF15387.6 EGC28506.1 - 1.6 9.0 6.7 5 7.4 0.8 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CLN3 PF02487.17 EGC28507.1 - 4.4 6.2 6.7 5.7 5.9 6.7 1.3 1 0 0 1 1 1 0 CLN3 protein CBFD_NFYB_HMF PF00808.23 EGC28508.1 - 1e-19 70.6 0.4 1.3e-19 70.2 0.4 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC28508.1 - 7.3e-15 55.5 0.3 9.3e-15 55.1 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-X PF09415.10 EGC28508.1 - 0.014 15.7 0.1 0.019 15.3 0.1 1.3 1 0 0 1 1 1 0 CENP-S associating Centromere protein X Peptidase_M26_N PF05342.14 EGC28508.1 - 0.017 14.5 0.0 0.018 14.5 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region zf-HIT PF04438.16 EGC28509.1 - 8e-06 25.6 7.3 1.3e-05 24.9 7.3 1.3 1 0 0 1 1 1 1 HIT zinc finger Peptidase_C54 PF03416.19 EGC28510.1 - 5.2e-23 81.8 0.0 5.2e-23 81.8 0.0 2.4 2 1 0 2 2 2 1 Peptidase family C54 PepSY_TM PF03929.16 EGC28510.1 - 2.1 7.9 4.0 2.8 7.5 4.0 1.1 1 0 0 1 1 1 0 PepSY-associated TM region Pex14_N PF04695.13 EGC28510.1 - 7.9 7.1 30.6 4.7 7.9 23.6 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Methyltrans_SAM PF10672.9 EGC28511.1 - 9e-25 87.4 0.0 1.4e-24 86.8 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Cons_hypoth95 PF03602.15 EGC28511.1 - 5e-05 23.0 0.0 9.9e-05 22.0 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EGC28511.1 - 0.017 15.8 0.0 0.034 14.8 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGC28511.1 - 0.021 14.4 0.0 0.052 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_15 PF09445.10 EGC28511.1 - 0.039 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Pirin PF02678.16 EGC28512.1 - 7.8e-28 96.6 0.0 1.4e-27 95.8 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGC28512.1 - 1.3e-11 44.7 0.0 2.3e-08 34.3 0.0 2.7 2 1 0 2 2 2 1 Pirin C-terminal cupin domain Cupin_2 PF07883.11 EGC28512.1 - 0.012 15.3 0.0 0.058 13.1 0.1 1.9 2 0 0 2 2 2 0 Cupin domain zf-CCCH PF00642.24 EGC28513.1 - 0.013 15.4 3.4 0.022 14.7 3.4 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGC28513.1 - 0.18 11.7 3.7 0.34 10.8 3.7 1.4 1 0 0 1 1 1 0 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGC28513.1 - 0.24 11.5 6.8 0.54 10.4 6.8 1.6 1 0 0 1 1 1 0 Zinc finger domain DUF2890 PF11081.8 EGC28513.1 - 1.4 9.0 6.1 4.6 7.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2890) MIF4G PF02854.19 EGC28514.1 - 1.4e-19 70.6 17.4 6.7e-19 68.4 10.0 3.0 2 0 0 2 2 2 2 MIF4G domain MA3 PF02847.17 EGC28514.1 - 1.1e-17 64.0 7.4 2.5e-17 62.9 2.9 2.8 2 0 0 2 2 2 1 MA3 domain Pyr_redox_2 PF07992.14 EGC28515.1 - 5e-08 32.5 0.0 1.2e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC28515.1 - 6e-06 25.7 0.3 1.2e-05 24.7 0.3 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGC28515.1 - 0.0005 20.1 0.1 0.016 15.2 0.1 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGC28515.1 - 0.0006 19.1 0.0 0.011 14.9 0.0 2.3 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) PUB PF09409.10 EGC28515.1 - 0.017 15.1 0.4 0.036 14.0 0.4 1.5 1 0 0 1 1 1 0 PUB domain SGP PF17228.2 EGC28516.1 - 0.24 12.3 8.8 0.28 12.1 8.8 1.2 1 0 0 1 1 1 0 Sulphur globule protein ABC2_membrane_5 PF13346.6 EGC28517.1 - 0.00091 18.8 5.5 0.00091 18.8 5.5 2.2 3 0 0 3 3 3 1 ABC-2 family transporter protein MARVEL PF01284.23 EGC28517.1 - 0.0051 16.8 10.0 0.0051 16.8 10.0 2.3 2 1 0 2 2 2 1 Membrane-associating domain TMEM190 PF15431.6 EGC28517.1 - 0.06 13.5 0.0 0.19 11.9 0.0 1.8 2 0 0 2 2 2 0 Transmembrane protein 190 TMIE PF16038.5 EGC28517.1 - 0.16 11.9 1.2 0.3 11.0 0.0 2.0 2 1 1 3 3 3 0 TMIE protein DUF4131 PF13567.6 EGC28517.1 - 0.31 10.7 6.5 0.15 11.7 0.7 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) Claudin_3 PF06653.11 EGC28517.1 - 0.55 10.2 14.4 0.78 9.7 0.8 2.9 2 1 1 3 3 3 0 Tight junction protein, Claudin-like SUR7 PF06687.12 EGC28517.1 - 0.67 9.5 19.1 7.7 6.1 17.2 2.7 1 1 1 2 2 2 0 SUR7/PalI family Claudin_2 PF13903.6 EGC28517.1 - 2 8.2 12.4 0.13 12.0 6.0 2.0 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Wzy_C PF04932.15 EGC28517.1 - 6.2 6.4 11.5 16 5.1 9.4 2.2 1 1 0 2 2 2 0 O-Antigen ligase DUF2207 PF09972.9 EGC28517.1 - 7.9 5.1 14.6 13 4.4 0.1 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) MS_channel PF00924.18 EGC28517.1 - 8.4 5.9 7.6 13 5.2 7.6 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel SRTM1 PF15872.5 EGC28518.1 - 0.07 13.3 0.1 0.34 11.1 0.0 1.9 2 0 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 zf-C3HC4_3 PF13920.6 EGC28519.1 - 6.5e-07 29.1 6.6 1.4e-06 28.0 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC28519.1 - 1.9e-05 24.4 5.1 1.9e-05 24.4 5.1 2.4 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC28519.1 - 2.1e-05 24.3 11.6 0.0002 21.1 11.5 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC28519.1 - 0.00033 20.5 10.7 0.00093 19.1 10.7 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGC28519.1 - 0.00046 20.5 8.7 0.00046 20.5 8.7 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGC28519.1 - 0.0064 16.7 6.2 0.014 15.6 6.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC28519.1 - 0.0073 16.1 7.2 0.021 14.7 7.2 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC28519.1 - 0.01 16.0 10.9 0.012 15.7 4.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC28519.1 - 0.079 12.8 8.1 0.15 11.8 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 EGC28519.1 - 0.12 12.6 1.3 0.32 11.3 1.3 1.7 1 0 0 1 1 1 0 zinc-ribbon zf-RING_UBOX PF13445.6 EGC28519.1 - 0.15 12.1 12.6 3.2 7.9 11.5 3.0 1 1 1 2 2 2 0 RING-type zinc-finger Helicase_Sgs1 PF11408.8 EGC28520.1 - 0.057 13.5 0.4 0.084 12.9 0.4 1.3 1 0 0 1 1 1 0 Sgs1 RecQ helicase RasGAP PF00616.19 EGC28522.1 - 4.3e-38 131.1 0.4 2.5e-24 86.2 0.1 2.9 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGC28522.1 - 3.8e-24 84.9 0.2 1.6e-23 82.9 0.1 2.1 2 0 0 2 2 2 1 C2 domain Mito_fiss_reg PF05308.11 EGC28522.1 - 0.065 13.3 0.3 0.065 13.3 0.3 3.0 3 0 0 3 3 3 0 Mitochondrial fission regulator RtcB PF01139.17 EGC28523.1 - 2.6e-143 478.1 0.0 3e-143 477.9 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB Peptidase_M41 PF01434.18 EGC28526.1 - 0.0062 16.4 5.6 0.009 15.9 5.6 1.3 1 0 0 1 1 1 1 Peptidase family M41 KxDL PF10241.9 EGC28526.1 - 0.14 12.5 8.0 0.23 11.8 0.9 2.5 2 0 0 2 2 2 0 Uncharacterized conserved protein FadA PF09403.10 EGC28526.1 - 0.31 11.6 9.7 0.63 10.6 8.8 1.9 1 1 0 1 1 1 0 Adhesion protein FadA s48_45 PF07422.13 EGC28526.1 - 0.5 11.0 6.1 1.3 9.6 5.9 2.0 1 1 0 1 1 1 0 Sexual stage antigen s48/45 domain Noelin-1 PF12308.8 EGC28527.1 - 0.68 9.9 4.5 1.2 9.1 1.3 2.3 1 1 1 2 2 2 0 Neurogenesis glycoprotein YnfE PF17452.2 EGC28527.1 - 0.7 10.2 4.2 0.8 10.0 0.3 2.4 2 0 0 2 2 2 0 Uncharacterized YnfE-like DUF3573 PF12097.8 EGC28527.1 - 1.8 7.3 6.4 1 8.1 5.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) SF3a60_bindingd PF12108.8 EGC28527.1 - 4.2 7.3 6.0 20 5.2 0.1 3.1 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain UQ_con PF00179.26 EGC28528.1 - 8.9e-37 125.9 0.1 1.1e-36 125.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC28528.1 - 0.018 15.3 0.7 0.088 13.1 0.0 2.0 2 0 0 2 2 2 0 RWD domain Cwf_Cwc_15 PF04889.12 EGC28528.1 - 0.19 11.4 13.4 0.24 11.1 13.4 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF4611 PF15387.6 EGC28528.1 - 0.31 11.3 5.7 0.57 10.4 5.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF3246 PF11596.8 EGC28528.1 - 0.46 9.9 7.3 0.63 9.4 7.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) DUF2457 PF10446.9 EGC28528.1 - 0.54 9.4 14.3 0.68 9.0 14.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) UPF0560 PF10577.9 EGC28528.1 - 1.4 7.3 6.7 1.8 6.9 6.7 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 RXT2_N PF08595.11 EGC28528.1 - 2 8.4 6.5 3.4 7.7 6.5 1.3 1 0 0 1 1 1 0 RXT2-like, N-terminal NOA36 PF06524.12 EGC28528.1 - 5.8 6.2 13.1 7.1 5.8 13.1 1.1 1 0 0 1 1 1 0 NOA36 protein Fis1_TPR_C PF14853.6 EGC28529.1 - 1.4e-07 31.5 0.6 3.5e-07 30.2 0.6 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_2 PF07719.17 EGC28529.1 - 0.0017 18.3 0.6 0.027 14.6 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.6 EGC28529.1 - 0.017 14.8 0.1 0.028 14.1 0.1 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_12 PF13424.6 EGC28529.1 - 0.098 13.0 0.1 0.17 12.2 0.1 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC28529.1 - 0.19 12.0 3.3 0.25 11.7 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Aa_trans PF01490.18 EGC28531.1 - 6.8e-11 41.5 33.7 1.7e-10 40.2 33.4 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGC28531.1 - 0.00034 19.8 19.4 0.00034 19.8 19.4 2.8 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DUF2508 PF10704.9 EGC28532.1 - 0.059 13.6 1.2 0.059 13.6 1.2 5.0 3 1 1 4 4 4 0 Protein of unknown function (DUF2508) Pkinase PF00069.25 EGC28533.1 - 2.1e-62 210.9 0.0 6.5e-62 209.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28533.1 - 5.4e-46 157.0 0.0 9.2e-46 156.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC28533.1 - 1.1e-06 28.3 0.0 4.5e-05 22.9 0.0 2.4 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGC28533.1 - 0.002 17.0 1.1 0.0029 16.4 0.0 1.9 2 1 0 2 2 2 1 Fungal protein kinase Apis_Csd PF11671.8 EGC28533.1 - 0.25 11.3 25.1 2 8.4 9.0 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein LRR_6 PF13516.6 EGC28536.1 - 4.9e-08 32.4 1.1 1.6 9.0 0.0 5.3 5 0 0 5 5 5 4 Leucine Rich repeat LRR_1 PF00560.33 EGC28536.1 - 0.00027 21.1 18.2 6.5 7.7 1.5 6.4 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_4 PF12799.7 EGC28536.1 - 0.0013 19.1 10.3 3 8.4 0.4 4.8 2 1 2 5 5 5 4 Leucine Rich repeats (2 copies) EGF_2 PF07974.13 EGC28537.1 - 0.00017 21.9 29.6 0.00086 19.6 9.8 3.3 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC28537.1 - 0.27 11.4 23.7 2.4 8.4 7.0 2.9 2 0 0 2 2 2 0 Laminin EGF domain LRR_6 PF13516.6 EGC28537.1 - 0.65 10.2 4.5 0.8 9.9 0.9 3.3 2 0 0 2 2 2 0 Leucine Rich repeat EGF_alliinase PF04863.13 EGC28537.1 - 7.1 7.1 17.7 0.65 10.4 3.9 2.7 2 0 0 2 2 2 0 Alliinase EGF-like domain TIG PF01833.24 EGC28538.1 - 2.1e-05 24.5 2.7 2.1e-05 24.5 2.7 4.7 4 2 1 5 5 5 2 IPT/TIG domain OST_IS PF18246.1 EGC28538.1 - 0.13 12.5 2.1 9.4 6.6 0.1 3.6 3 0 0 3 3 3 0 Oligosaccharyltransferase Insert domain SNF2_N PF00176.23 EGC28539.1 - 1.8e-69 234.2 0.5 4.8e-69 232.7 0.5 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC28539.1 - 2.1e-18 66.7 0.0 2.1e-18 66.7 0.0 3.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.13 EGC28539.1 - 1.3e-15 57.5 2.0 1.3e-15 57.5 2.0 3.8 2 1 0 2 2 2 1 HSA Myb_DNA-bind_6 PF13921.6 EGC28539.1 - 1.5e-05 25.1 0.7 0.00013 22.2 0.7 2.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGC28539.1 - 2.1e-05 24.6 0.1 6.5e-05 23.0 0.1 1.9 1 0 0 1 1 1 1 Myb-like DNA-binding domain HTH_54 PF18607.1 EGC28539.1 - 0.086 12.9 6.6 3.3 7.9 0.0 4.0 3 0 0 3 3 3 0 ParA helix turn helix domain NFACT-C PF11923.8 EGC28539.1 - 0.38 10.7 5.0 4.9 7.1 5.0 3.0 1 0 0 1 1 1 0 NFACT protein C-terminal domain Adaptin_N PF01602.20 EGC28540.1 - 1.1e-125 420.2 18.3 1.8e-125 419.5 18.3 1.4 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGC28540.1 - 5.4e-20 72.1 8.5 1.3e-18 67.6 0.9 4.7 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 AP3B1_C PF14796.6 EGC28540.1 - 6.4e-14 52.5 0.2 1.5e-13 51.2 0.2 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT_2 PF13646.6 EGC28540.1 - 7.1e-09 35.9 0.3 0.0011 19.3 0.1 3.9 2 2 1 4 4 4 3 HEAT repeats HEAT PF02985.22 EGC28540.1 - 2.8e-07 30.2 4.7 0.034 14.4 0.0 6.2 8 0 0 8 8 8 2 HEAT repeat HEAT_EZ PF13513.6 EGC28540.1 - 0.00024 21.5 0.3 2.8 8.6 0.1 4.5 3 1 1 4 4 4 3 HEAT-like repeat MOR2-PAG1_C PF14225.6 EGC28540.1 - 0.0084 16.0 0.3 0.028 14.3 0.3 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal Cohesin_HEAT PF12765.7 EGC28540.1 - 6.9 7.1 9.3 6.4 7.2 0.1 4.6 5 0 0 5 5 5 0 HEAT repeat associated with sister chromatid cohesion CBF PF03914.17 EGC28542.1 - 4.8e-35 121.1 1.0 2.6e-34 118.7 0.1 2.4 2 1 0 2 2 2 1 CBF/Mak21 family SNARE_assoc PF09335.11 EGC28543.1 - 0.011 16.2 5.2 0.011 16.2 5.2 1.7 2 1 0 2 2 2 0 SNARE associated Golgi protein ATG16 PF08614.11 EGC28544.1 - 3.8e-48 164.4 17.1 5e-48 164.0 17.1 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.32 EGC28544.1 - 4.2e-34 116.0 23.9 6.5e-06 26.8 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC28544.1 - 2.6e-13 50.1 2.2 2.1e-05 24.7 0.2 5.1 3 2 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC28544.1 - 1.3e-05 25.2 0.7 0.16 11.8 0.0 4.0 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGC28544.1 - 2.3e-05 23.9 0.4 0.0027 17.1 0.3 3.2 1 1 1 2 2 2 1 WD40-like domain KASH_CCD PF14662.6 EGC28544.1 - 0.0098 15.7 13.2 0.0098 15.7 13.2 2.3 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Ge1_WD40 PF16529.5 EGC28544.1 - 0.012 14.5 1.9 0.92 8.4 0.0 3.4 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein ERM PF00769.19 EGC28544.1 - 0.017 14.9 17.0 0.027 14.3 17.0 1.2 1 0 0 1 1 1 0 Ezrin/radixin/moesin family DUF2192 PF09958.9 EGC28544.1 - 0.022 14.3 2.2 0.051 13.1 2.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2192) DUF4715 PF15835.5 EGC28544.1 - 0.044 13.9 0.8 0.077 13.1 0.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4715) PALB2_WD40 PF16756.5 EGC28544.1 - 0.056 12.4 4.8 5.3 5.9 0.1 3.6 3 1 0 4 4 4 0 Partner and localizer of BRCA2 WD40 domain Serglycin PF04360.12 EGC28544.1 - 0.13 12.2 6.8 0.067 13.1 4.1 2.0 2 1 0 2 2 1 0 Serglycin Fez1 PF06818.15 EGC28544.1 - 0.15 12.5 19.4 1.1 9.7 18.5 2.1 1 1 1 2 2 2 0 Fez1 DUF4407 PF14362.6 EGC28544.1 - 2.1 7.6 10.2 3.4 6.9 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF724 PF05266.14 EGC28544.1 - 3.2 7.5 17.8 2.8 7.7 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF724) V_ATPase_I PF01496.19 EGC28544.1 - 5.1 4.9 12.6 7.2 4.4 12.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2_jaz PF12171.8 EGC28545.1 - 8.7e-09 35.5 4.8 8.7e-09 35.5 4.7 1.7 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGC28545.1 - 0.0054 17.1 3.1 0.01 16.3 3.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGC28545.1 - 0.018 15.4 2.0 0.018 15.4 2.0 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGC28545.1 - 0.023 15.1 2.3 0.047 14.1 2.3 1.6 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGC28545.1 - 0.051 14.4 1.5 0.1 13.5 1.5 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger AKAP95 PF04988.12 EGC28545.1 - 0.1 12.8 1.2 0.1 12.8 1.2 1.9 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) Pkinase PF00069.25 EGC28547.1 - 1.9e-44 152.0 3.3 1.5e-34 119.6 0.2 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28547.1 - 5.9e-30 104.4 0.4 1.6e-23 83.3 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Acetyltransf_1 PF00583.25 EGC28547.1 - 3.9e-07 30.3 0.0 9.3e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC28547.1 - 5.8e-06 26.3 0.0 8.1e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC28547.1 - 0.0003 21.2 0.0 0.00075 19.9 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Kinase-like PF14531.6 EGC28547.1 - 0.0044 16.4 0.0 0.0069 15.7 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Acetyltransf_CG PF14542.6 EGC28547.1 - 0.0047 17.0 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Pkinase_fungal PF17667.1 EGC28547.1 - 0.013 14.3 0.1 0.025 13.4 0.1 1.5 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGC28547.1 - 0.18 11.1 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NPV_P10 PF05531.12 EGC28548.1 - 0.03 14.8 3.6 0.03 14.8 3.6 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF5342 PF17277.2 EGC28548.1 - 0.048 14.0 0.3 0.11 12.8 0.3 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5342) FRB_dom PF08771.11 EGC28548.1 - 0.083 13.3 5.6 0.081 13.3 1.3 2.3 2 1 0 2 2 2 0 FKBP12-rapamycin binding domain YtxH PF12732.7 EGC28548.1 - 0.11 13.1 0.3 0.34 11.5 0.3 1.9 1 1 0 1 1 1 0 YtxH-like protein DUF489 PF04356.12 EGC28548.1 - 0.15 12.1 6.0 0.16 11.9 6.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Exonuc_VII_L PF02601.15 EGC28548.1 - 0.57 9.7 6.6 0.64 9.5 6.6 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2203 PF09969.9 EGC28548.1 - 1.5 9.6 6.2 1.7 9.4 1.4 2.2 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF948 PF06103.11 EGC28548.1 - 2 8.7 5.9 0.87 9.9 1.9 2.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) BTB PF00651.31 EGC28549.1 - 1.2e-07 31.9 1.2 2.4e-07 31.0 1.2 1.5 1 0 0 1 1 1 1 BTB/POZ domain PAW PF04721.17 EGC28549.1 - 0.0075 16.1 1.7 0.0075 16.1 1.7 2.3 2 1 0 2 2 2 1 PNGase C-terminal domain, mannose-binding module PAW SAM_2 PF07647.17 EGC28549.1 - 0.043 13.9 0.1 0.4 10.8 0.1 2.5 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) Pkr1 PF08636.10 EGC28550.1 - 0.0069 16.5 0.7 0.011 15.9 0.7 1.3 1 0 0 1 1 1 1 ER protein Pkr1 Arm_vescicular PF18770.1 EGC28550.1 - 0.13 12.2 0.0 0.38 10.7 0.0 1.8 1 0 0 1 1 1 0 Armadillo tether-repeat of vescicular transport factor DUF4083 PF13314.6 EGC28550.1 - 0.4 10.7 3.1 1.7 8.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Pns11_12 PF17464.2 EGC28552.1 - 0.0051 16.5 0.0 0.0057 16.4 0.0 1.0 1 0 0 1 1 1 1 Non-structural protein 11 and 12 DUF4699 PF15770.5 EGC28553.1 - 0.073 12.8 0.7 0.086 12.6 0.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4699) DUF3439 PF11921.8 EGC28554.1 - 0.12 12.3 3.2 0.29 11.1 3.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAM_2 PF07647.17 EGC28555.1 - 0.0099 16.0 1.1 0.023 14.8 0.1 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC28555.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) Glu_syn_central PF04898.14 EGC28555.1 - 0.065 12.7 0.0 0.085 12.3 0.0 1.2 1 0 0 1 1 1 0 Glutamate synthase central domain DUF4691 PF15762.5 EGC28555.1 - 0.089 12.9 0.0 0.12 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4691) Pkinase PF00069.25 EGC28556.1 - 4.7e-43 147.4 0.8 1.4e-36 126.2 0.0 3.2 3 1 1 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28556.1 - 1.3e-19 70.6 0.0 5.6e-18 65.1 0.0 2.3 1 1 1 2 2 2 1 Protein tyrosine kinase SAM_1 PF00536.30 EGC28556.1 - 1.6e-06 28.5 0.1 4.3e-06 27.1 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC28556.1 - 2.7e-05 24.2 0.1 6.6e-05 22.9 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RIO1 PF01163.22 EGC28556.1 - 0.00032 20.3 0.0 0.00073 19.2 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGC28556.1 - 0.00039 20.4 0.2 0.0006 19.8 0.2 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC28556.1 - 0.015 14.6 0.0 0.027 13.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGC28557.1 - 3.8e-57 193.7 0.0 6.7e-57 192.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28557.1 - 7.4e-31 107.4 0.0 1.2e-30 106.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 EGC28557.1 - 2.7e-08 34.1 0.2 8.1e-08 32.6 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 EGC28557.1 - 6.1e-06 26.3 0.0 0.00055 19.9 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family SAM_2 PF07647.17 EGC28557.1 - 0.00017 21.7 0.1 0.00041 20.4 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RIO1 PF01163.22 EGC28557.1 - 0.0004 20.0 0.1 0.00068 19.3 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGC28557.1 - 0.11 11.8 0.1 0.19 11.1 0.1 1.4 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC28557.1 - 0.13 11.6 0.2 0.31 10.3 0.0 1.8 2 1 0 2 2 2 0 Kinase-like BRCT PF00533.26 EGC28558.1 - 1.6e-56 188.6 12.6 9.5e-15 54.7 0.1 8.4 8 0 0 8 8 8 6 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC28558.1 - 2.7e-36 123.8 13.8 1.5e-07 31.7 0.1 7.9 7 0 0 7 7 7 7 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC28558.1 - 3.5e-36 122.9 3.7 2.7e-11 43.3 0.0 7.0 7 1 0 7 7 7 4 twin BRCT domain LIG3_BRCT PF16759.5 EGC28558.1 - 1.2e-18 67.1 1.9 0.00012 22.3 0.1 7.0 7 0 0 7 7 7 4 DNA ligase 3 BRCT domain BRCT_3 PF18428.1 EGC28558.1 - 4.7e-10 39.4 0.5 0.28 11.3 0.0 6.4 5 1 1 6 6 6 2 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGC28558.1 - 0.002 18.0 0.0 1.1 9.2 0.0 4.5 5 1 0 5 5 5 1 Regulator of Ty1 transposition protein 107 BRCT domain Nup35_RRM PF05172.13 EGC28558.1 - 0.0045 16.9 0.6 0.032 14.2 0.0 2.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif F-box-like PF12937.7 EGC28559.1 - 0.074 13.0 0.2 0.22 11.5 0.2 1.9 1 0 0 1 1 1 0 F-box-like DUF3439 PF11921.8 EGC28559.1 - 0.17 11.8 2.6 0.38 10.7 2.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) STATa_Ig PF18214.1 EGC28560.1 - 6.4e-08 32.6 5.1 0.00016 21.7 0.0 3.5 2 1 0 2 2 2 2 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 EGC28560.1 - 0.019 15.4 1.4 0.3 11.6 0.6 3.0 1 1 0 2 2 2 0 EF-hand fold domain AATF-Che1 PF13339.6 EGC28561.1 - 9e-29 100.9 9.4 9e-29 100.9 9.4 4.0 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.12 EGC28561.1 - 1.2e-22 80.2 1.5 1.2e-22 80.2 1.5 3.8 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal DUF4447 PF14590.6 EGC28561.1 - 0.0086 15.9 0.2 0.0086 15.9 0.2 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4447) GP40 PF11025.8 EGC28563.1 - 0.012 15.4 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF3042 PF11240.8 EGC28563.1 - 0.048 13.7 3.6 1.3 9.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) Tim17 PF02466.19 EGC28563.1 - 0.054 13.9 4.3 0.16 12.3 4.3 1.8 1 1 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family NUDIX_2 PF13869.6 EGC28564.1 - 1.4e-74 249.8 0.1 1.6e-74 249.6 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.28 EGC28564.1 - 0.0011 19.1 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Mito_carr PF00153.27 EGC28565.1 - 1.6e-69 229.9 7.6 8.3e-24 83.3 0.2 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGC28565.1 - 0.019 14.1 0.1 1.5 7.9 0.0 2.6 2 0 0 2 2 2 0 Gammaproteobacterial serine protease PQ-loop PF04193.14 EGC28566.1 - 1.2e-08 34.6 12.8 2.2e-07 30.5 1.3 3.3 4 0 0 4 4 4 2 PQ loop repeat DUF4199 PF13858.6 EGC28566.1 - 0.028 14.8 0.2 0.028 14.8 0.2 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF4199) DUF4010 PF13194.6 EGC28566.1 - 0.029 14.0 2.3 1.6 8.3 0.1 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4010) Macoilin PF09726.9 EGC28566.1 - 0.033 12.7 0.1 0.033 12.7 0.1 1.1 1 0 0 1 1 1 0 Macoilin family DUF3290 PF11694.8 EGC28566.1 - 0.034 14.1 0.7 0.19 11.7 0.7 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) RIFIN PF02009.16 EGC28566.1 - 0.052 13.4 0.3 0.052 13.4 0.3 2.0 2 0 0 2 2 2 0 Rifin Orthoreo_P10 PF07204.11 EGC28566.1 - 0.058 13.3 0.0 0.18 11.8 0.0 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF4079 PF13301.6 EGC28566.1 - 0.064 13.4 0.0 4.4 7.5 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4079) CrgA PF06781.12 EGC28566.1 - 0.087 12.9 1.9 0.91 9.6 0.0 3.0 2 1 0 2 2 2 0 Cell division protein CrgA EphA2_TM PF14575.6 EGC28566.1 - 0.2 12.6 0.0 0.2 12.6 0.0 3.3 3 1 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain DUF2207 PF09972.9 EGC28566.1 - 0.4 9.4 11.6 6.1 5.5 4.0 3.0 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) TMEM208_SND2 PF05620.11 EGC28566.1 - 0.74 9.6 0.0 0.74 9.6 0.0 2.7 3 0 0 3 3 3 0 SRP-independent targeting protein 2/TMEM208 DUF2627 PF11118.8 EGC28566.1 - 1.3 9.7 4.5 3.9 8.1 0.0 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2627) DUF2681 PF10883.8 EGC28566.1 - 2.3 8.7 11.1 0.44 11.0 0.4 3.6 4 0 0 4 4 3 0 Protein of unknown function (DUF2681) PI3K_1B_p101 PF10486.9 EGC28566.1 - 2.5 5.8 7.1 3.4 5.3 7.1 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit CC190 PF15768.5 EGC28566.1 - 4.3 7.3 9.1 6.9 6.6 9.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 190 Spore_YhaL PF14147.6 EGC28566.1 - 5.8 6.7 5.7 1 9.1 0.2 2.6 2 0 0 2 2 1 0 Sporulation protein YhaL DUF2070 PF09843.9 EGC28566.1 - 7.6 4.7 12.4 0.35 9.1 4.8 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Fe-ADH PF00465.19 EGC28567.1 - 7.6e-95 317.8 0.0 9.3e-95 317.5 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGC28567.1 - 3.4e-07 30.2 0.0 0.00054 19.7 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase FNIP PF05725.12 EGC28568.1 - 1.6e-36 124.2 61.3 6e-05 23.1 1.4 12.5 6 2 7 14 14 14 13 FNIP Repeat AAA_3 PF07726.11 EGC28568.1 - 0.024 14.5 4.6 53 3.7 0.0 5.9 1 1 7 8 8 8 0 ATPase family associated with various cellular activities (AAA) Aminotran_1_2 PF00155.21 EGC28569.1 - 2.9e-15 56.3 0.0 3.2e-15 56.2 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II PIG-P PF08510.12 EGC28570.1 - 8.1e-37 125.8 5.9 9e-37 125.7 5.9 1.0 1 0 0 1 1 1 1 PIG-P DUF1279 PF06916.13 EGC28570.1 - 0.02 15.5 0.4 0.033 14.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1279) DPM2 PF07297.12 EGC28570.1 - 0.034 14.5 11.5 0.047 14.0 11.5 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) Tmemb_9 PF05434.11 EGC28570.1 - 1.3 8.9 3.5 0.38 10.7 0.3 1.7 1 1 1 2 2 2 0 TMEM9 P2X_receptor PF00864.19 EGC28571.1 - 9.9e-15 54.5 4.3 5.3e-10 38.9 2.3 3.1 1 1 1 2 2 2 2 ATP P2X receptor ELO PF01151.18 EGC28573.1 - 3.4e-62 210.2 30.5 4e-62 210.0 30.5 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF5399 PF17377.2 EGC28573.1 - 0.15 11.9 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5399) Spy1 PF11357.8 EGC28574.1 - 1.5e-10 41.5 6.5 1.6e-05 25.2 1.2 2.7 2 1 1 3 3 3 2 Cell cycle regulatory protein DUF2121 PF09894.9 EGC28574.1 - 0.048 13.2 3.3 0.048 13.2 1.7 1.8 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2121) Sugar_transport PF06800.12 EGC28574.1 - 0.11 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein DUF4500 PF14937.6 EGC28575.1 - 1.9 8.6 6.3 0.75 9.9 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4500) Laminin_EGF PF00053.24 EGC28576.1 - 0.01 15.9 7.7 0.01 15.9 7.7 2.9 3 0 0 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC28576.1 - 0.017 15.5 15.3 0.017 15.5 15.3 2.7 2 0 0 2 2 2 0 EGF-like domain TIG PF01833.24 EGC28576.1 - 0.027 14.5 0.1 0.027 14.5 0.1 4.5 3 1 2 5 5 5 0 IPT/TIG domain DDE_3 PF13358.6 EGC28577.1 - 2.2e-13 50.2 0.0 2.3e-13 50.1 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_2 PF07719.17 EGC28578.1 - 3.9e-05 23.5 3.4 3 8.2 0.3 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC28578.1 - 0.068 13.0 13.3 5.3 7.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Histone PF00125.24 EGC28579.1 - 6e-11 42.8 0.0 7.1e-11 42.6 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGC28579.1 - 5.2e-07 29.3 0.0 9.1e-07 28.5 0.0 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A CBFD_NFYB_HMF PF00808.23 EGC28579.1 - 3.6e-05 24.0 0.0 4.3e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone PIP5K PF01504.18 EGC28582.1 - 4.3e-27 95.0 9.6 4.3e-27 95.0 9.6 3.4 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Sigma70_ner PF04546.13 EGC28582.1 - 2.8 7.8 16.7 3 7.7 14.2 2.1 2 0 0 2 2 2 0 Sigma-70, non-essential region Cnn_1N PF07989.11 EGC28583.1 - 0.0022 18.1 6.3 0.0037 17.4 6.3 1.6 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 TMCO5 PF14992.6 EGC28583.1 - 0.03 13.9 9.4 0.033 13.8 9.4 1.1 1 0 0 1 1 1 0 TMCO5 family Orthopox_F6 PF06601.12 EGC28583.1 - 0.12 12.5 1.8 0.17 12.0 0.7 1.8 1 1 1 2 2 2 0 Orthopoxvirus F6 protein Mod_r PF07200.13 EGC28583.1 - 0.25 11.5 12.9 0.035 14.2 9.0 1.5 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein IFP_35_N PF07334.13 EGC28583.1 - 0.41 10.8 7.7 0.69 10.0 6.7 1.9 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus AAA_23 PF13476.6 EGC28583.1 - 0.43 11.0 13.1 0.5 10.8 13.1 1.0 1 0 0 1 1 1 0 AAA domain eIF-4B PF06273.11 EGC28583.1 - 6.2 5.7 6.2 9.9 5.1 6.2 1.4 1 1 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B FANCAA PF15146.6 EGC28584.1 - 0.0038 16.4 0.0 0.0067 15.6 0.0 1.3 1 0 0 1 1 1 1 Fanconi anemia-associated FNIP PF05725.12 EGC28585.1 - 1.8e-27 95.2 14.6 1.5e-09 37.9 3.9 4.5 3 1 1 4 4 4 4 FNIP Repeat LRR_5 PF13306.6 EGC28585.1 - 2.4e-05 24.3 0.3 0.00069 19.6 0.0 2.7 1 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) WD40 PF00400.32 EGC28588.1 - 1.8e-49 164.7 36.6 4.2e-06 27.4 0.2 11.6 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC28588.1 - 3.7e-21 75.2 4.8 1e-05 25.8 0.0 9.1 4 3 6 10 10 10 4 Anaphase-promoting complex subunit 4 WD40 domain Utp12 PF04003.12 EGC28588.1 - 9.2e-17 61.3 0.0 1.6e-16 60.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family WD40_like PF17005.5 EGC28588.1 - 1.5e-10 40.9 5.7 0.003 16.9 1.0 4.7 3 2 1 4 4 4 4 WD40-like domain Ge1_WD40 PF16529.5 EGC28588.1 - 1.1e-06 27.9 7.4 0.0097 14.9 0.0 6.0 3 2 4 7 7 7 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC28588.1 - 5.4e-05 22.0 2.0 0.0053 15.5 0.1 4.0 3 1 1 4 4 4 1 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGC28588.1 - 0.01 15.2 0.0 3.8 6.8 0.0 2.6 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.11 EGC28588.1 - 0.012 14.4 15.1 0.32 9.7 0.0 5.5 1 1 0 4 4 4 0 Nup133 N terminal like DUF4047 PF13256.6 EGC28588.1 - 6.7 6.9 6.7 1.6 9.0 0.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) FNIP PF05725.12 EGC28589.1 - 1.5e-23 82.7 2.6 6.1e-12 45.5 0.9 2.0 2 0 0 2 2 2 2 FNIP Repeat Med21 PF11221.8 EGC28590.1 - 9.4e-17 61.6 5.0 9.4e-17 61.6 5.0 2.8 1 1 1 2 2 2 1 Subunit 21 of Mediator complex DUF2452 PF10504.9 EGC28590.1 - 0.0037 16.7 0.9 0.0049 16.3 0.9 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) VIR_N PF15912.5 EGC28590.1 - 0.016 14.8 2.6 0.018 14.7 2.6 1.1 1 0 0 1 1 1 0 Virilizer, N-terminal Qua1 PF16274.5 EGC28590.1 - 0.74 9.7 12.9 0.58 10.0 0.2 2.5 2 0 0 2 2 2 0 Qua1 domain zf-Nse PF11789.8 EGC28591.1 - 1e-17 63.7 0.5 1.8e-17 62.9 0.5 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGC28591.1 - 0.00011 22.2 0.3 0.0002 21.3 0.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.20 EGC28591.1 - 0.0028 17.4 0.6 0.0048 16.6 0.6 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 EGC28591.1 - 0.023 14.8 0.2 0.045 13.9 0.2 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGC28591.1 - 0.028 14.3 0.1 0.057 13.3 0.1 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RAG1 PF10426.9 EGC28591.1 - 0.11 12.7 0.7 0.82 9.9 0.1 2.5 2 0 0 2 2 2 0 Recombination-activating protein 1 zinc-finger domain zf-C2H2_aberr PF17017.5 EGC28591.1 - 0.11 12.6 1.8 0.57 10.3 0.2 2.4 2 1 0 2 2 2 0 Aberrant zinc-finger zf-C3HC4 PF00097.25 EGC28591.1 - 0.16 11.9 0.9 0.24 11.3 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DAGK_cat PF00781.24 EGC28592.1 - 1.4e-19 70.0 0.0 2.5e-19 69.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Orf78 PF06024.12 EGC28592.1 - 0.049 13.9 0.9 0.049 13.9 0.9 4.7 5 0 0 5 5 5 0 Orf78 (ac78) DUF4263 PF14082.6 EGC28593.1 - 0.0085 16.4 1.8 0.011 16.0 1.4 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4263) POR_N PF01855.19 EGC28593.1 - 0.57 9.9 1.4 0.72 9.6 1.4 1.1 1 0 0 1 1 1 0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg TMPIT PF07851.13 EGC28593.1 - 4.3 6.5 5.3 2.4 7.3 3.7 1.3 1 1 0 1 1 1 0 TMPIT-like protein VPS9 PF02204.18 EGC28595.1 - 1.7e-22 79.6 0.2 5.8e-22 77.9 0.2 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.16 EGC28595.1 - 0.0016 18.1 0.0 0.0048 16.6 0.0 1.9 1 0 0 1 1 1 1 CUE domain DUF5601 PF18151.1 EGC28595.1 - 0.0052 17.1 0.3 0.0052 17.1 0.3 3.2 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) WD40 PF00400.32 EGC28596.1 - 7e-08 33.0 5.5 0.014 16.3 0.1 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat PD40 PF07676.12 EGC28596.1 - 0.0067 16.3 0.5 2.9 7.9 0.1 4.1 4 0 0 4 4 4 1 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGC28596.1 - 0.25 11.2 3.9 4 7.3 0.0 3.5 3 1 1 5 5 5 0 Eukaryotic translation initiation factor eIF2A AcMNPV_Ac109 PF05054.12 EGC28597.1 - 0.055 12.5 0.9 0.063 12.3 0.9 1.1 1 0 0 1 1 1 0 Autographa californica nuclear polyhedrosis virus (AcMNPV) protein DUF3439 PF11921.8 EGC28598.1 - 9.5 6.2 11.0 0.14 12.1 2.2 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.28 EGC28599.1 - 5.9e-33 114.9 1.2 7.8e-33 114.5 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TolB_N PF04052.13 EGC28599.1 - 0.02 15.0 0.0 0.08 13.1 0.0 2.0 2 0 0 2 2 2 0 TolB amino-terminal domain DIPSY PF11763.8 EGC28599.1 - 1.2 9.3 4.6 4.3 7.5 0.2 3.1 3 0 0 3 3 3 0 Cell-wall adhesin ligand-binding C-terminal PIG-S PF10510.9 EGC28600.1 - 0.18 10.6 10.0 0.022 13.6 5.8 1.5 2 0 0 2 2 2 0 Phosphatidylinositol-glycan biosynthesis class S protein RAMPs PF03787.15 EGC28600.1 - 0.34 10.9 8.2 4.6 7.2 0.1 2.3 2 0 0 2 2 2 0 RAMP superfamily Presenilin PF01080.17 EGC28600.1 - 2.8 6.6 13.8 0.23 10.2 8.3 1.9 2 0 0 2 2 2 0 Presenilin BUD22 PF09073.10 EGC28600.1 - 4.4 6.5 21.9 0.091 12.1 12.3 2.0 2 0 0 2 2 2 0 BUD22 Duffy_binding PF05424.11 EGC28600.1 - 6.5 6.8 16.1 0.42 10.6 4.4 2.5 2 0 0 2 2 2 0 Duffy binding domain FtsX PF02687.21 EGC28601.1 - 4.8e-13 49.4 21.5 4.4e-10 39.9 6.1 6.0 6 1 0 6 6 6 3 FtsX-like permease family Vac7 PF12751.7 EGC28601.1 - 4.6 6.6 8.0 7.8 5.8 8.0 1.2 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 TGT PF01702.18 EGC28602.1 - 6.4e-144 479.4 0.0 7.9e-144 479.1 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Isochorismatase PF00857.20 EGC28603.1 - 1.4e-36 126.3 0.1 1.6e-36 126.1 0.1 1.0 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 EGC28604.1 - 3.9e-43 147.6 0.7 4.4e-43 147.5 0.7 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.11 EGC28604.1 - 0.059 13.4 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Cloacin_immun PF03513.14 EGC28604.1 - 0.11 12.9 0.0 0.27 11.6 0.0 1.6 1 0 0 1 1 1 0 Cloacin immunity protein DEAD PF00270.29 EGC28605.1 - 2.2e-45 154.6 0.2 3.2e-45 154.0 0.2 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC28605.1 - 1.4e-27 96.3 2.6 8.5e-27 93.7 0.5 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC28605.1 - 4.7e-05 23.5 0.0 8.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP PF05725.12 EGC28609.1 - 5.9e-82 269.6 32.0 4.1e-15 55.7 0.7 7.9 5 1 4 9 9 9 9 FNIP Repeat DUF3439 PF11921.8 EGC28610.1 - 0.0094 15.9 2.9 0.016 15.2 2.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) DUF4805 PF16063.5 EGC28610.1 - 0.072 12.4 2.3 0.1 12.0 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4805) Menin PF05053.13 EGC28610.1 - 2.4 6.4 5.9 3.9 5.7 5.9 1.3 1 0 0 1 1 1 0 Menin Membralin PF09746.9 EGC28610.1 - 4.5 6.2 7.0 5.6 5.9 7.0 1.1 1 0 0 1 1 1 0 Tumour-associated protein Herpes_capsid PF06112.11 EGC28612.1 - 1.2 9.2 14.8 2 8.4 14.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PRP38_assoc PF12871.7 EGC28613.1 - 2.2 8.9 39.1 3.9 8.1 39.1 1.5 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SNARE_assoc PF09335.11 EGC28616.1 - 0.0014 19.1 0.1 0.014 15.8 0.1 2.0 2 0 0 2 2 2 1 SNARE associated Golgi protein DUF4834 PF16118.5 EGC28616.1 - 0.62 11.1 3.3 0.61 11.1 1.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) NmrA PF05368.13 EGC28617.1 - 2.5e-28 99.2 0.8 1e-20 74.3 0.1 2.2 1 1 1 2 2 2 2 NmrA-like family NAD_binding_10 PF13460.6 EGC28617.1 - 0.00018 21.4 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGC28618.1 - 3e-57 193.8 0.0 5.8e-57 192.9 0.0 1.4 2 0 0 2 2 2 1 NmrA-like family Ribosomal_S25 PF03297.15 EGC28618.1 - 2.9e-37 126.9 4.3 4.6e-37 126.3 4.3 1.3 1 0 0 1 1 1 1 S25 ribosomal protein NAD_binding_10 PF13460.6 EGC28618.1 - 1.4e-15 57.6 0.1 9.2e-15 55.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)H-binding Epimerase PF01370.21 EGC28618.1 - 8.7e-07 28.6 0.0 1.9e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGC28618.1 - 0.0031 17.8 0.0 0.0056 16.9 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain HTH_24 PF13412.6 EGC28618.1 - 0.0037 16.8 0.4 0.016 14.7 0.5 2.0 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.19 EGC28618.1 - 0.026 14.4 0.1 0.073 13.0 0.1 1.7 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB KR PF08659.10 EGC28618.1 - 0.029 14.3 0.0 0.065 13.1 0.0 1.6 1 0 0 1 1 1 0 KR domain F420_oxidored PF03807.17 EGC28618.1 - 0.042 14.4 0.0 0.13 12.9 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Fe_dep_repress PF01325.19 EGC28618.1 - 0.12 12.6 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Shikimate_DH PF01488.20 EGC28618.1 - 0.16 12.0 0.0 1.8 8.6 0.0 2.3 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase ARTD15_N PF18084.1 EGC28619.1 - 0.0021 18.3 0.1 0.0074 16.5 0.1 2.0 1 0 0 1 1 1 1 ARTD15 N-terminal domain Acyltransf_C PF16076.5 EGC28619.1 - 0.034 14.2 0.8 0.16 12.1 0.3 2.5 2 0 0 2 2 2 0 Acyltransferase C-terminus Abhydro_lipase PF04083.16 EGC28620.1 - 6.2e-20 70.6 0.5 1.1e-17 63.3 0.0 2.8 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC28620.1 - 4.8e-05 23.1 1.0 0.00045 19.9 1.0 2.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC28620.1 - 0.00021 20.6 0.1 0.1 11.9 0.0 3.2 3 0 0 3 3 3 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC28620.1 - 0.038 14.6 0.0 0.13 12.8 0.0 1.7 1 1 0 1 1 1 0 Alpha/beta hydrolase family Barttin PF15462.6 EGC28620.1 - 1.1 9.0 3.7 4.2 7.1 1.2 2.2 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF3439 PF11921.8 EGC28620.1 - 9 6.3 11.8 2.9 7.9 4.6 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FNIP PF05725.12 EGC28621.1 - 0.0013 18.8 1.2 0.0037 17.4 1.2 1.8 1 0 0 1 1 1 1 FNIP Repeat V-set PF07686.17 EGC28622.1 - 0.0068 16.6 0.1 0.015 15.4 0.0 1.5 1 1 0 1 1 1 1 Immunoglobulin V-set domain SET PF00856.28 EGC28624.1 - 5.2e-12 46.5 3.6 5.2e-12 46.5 3.6 2.5 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGC28624.1 - 5.7e-06 26.3 6.8 5.7e-06 26.3 6.8 2.0 2 0 0 2 2 2 1 MYND finger CpXC PF14353.6 EGC28624.1 - 5.2 7.1 10.8 2 8.5 0.1 3.2 3 1 0 3 3 3 0 CpXC protein SUIM_assoc PF16619.5 EGC28625.1 - 0.03 14.4 6.8 0.048 13.7 6.8 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Val_tRNA-synt_C PF10458.9 EGC28625.1 - 0.27 11.5 15.7 0.22 11.8 9.4 2.9 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm FapA PF03961.13 EGC28625.1 - 0.33 9.5 11.5 0.36 9.4 11.5 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A DUF724 PF05266.14 EGC28625.1 - 0.47 10.3 13.6 0.6 9.9 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) TMEM214 PF10151.9 EGC28625.1 - 0.53 8.7 10.4 0.51 8.7 10.4 1.0 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator V_ATPase_I PF01496.19 EGC28625.1 - 2.8 5.8 10.2 3.2 5.5 10.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Neur_chan_memb PF02932.16 EGC28625.1 - 5.4 7.0 6.8 5.5 7.0 6.8 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IATP PF04568.12 EGC28625.1 - 7.5 7.1 14.9 0.56 10.7 8.0 2.1 1 1 1 2 2 2 0 Mitochondrial ATPase inhibitor, IATP CLN3 PF02487.17 EGC28625.1 - 8.2 5.4 5.7 7.6 5.5 5.7 1.0 1 0 0 1 1 1 0 CLN3 protein Ureide_permease PF07168.11 EGC28625.1 - 8.7 5.0 5.3 9.7 4.8 5.3 1.0 1 0 0 1 1 1 0 Ureide permease eIF-1a PF01176.19 EGC28627.1 - 3.1e-12 46.1 0.5 4.9e-12 45.5 0.5 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DDE_Tnp_4 PF13359.6 EGC28627.1 - 0.044 13.5 0.2 0.059 13.0 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease CSD PF00313.22 EGC28628.1 - 0.16 11.9 0.2 42 4.1 0.3 3.0 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain SdrD_B PF17210.3 EGC28629.1 - 3.8e-38 130.2 5.8 1e-11 45.1 0.1 4.8 4 0 0 4 4 4 4 SdrD B-like domain CarboxypepD_reg PF13620.6 EGC28629.1 - 2.6e-11 43.6 1.3 0.0015 18.8 0.1 4.4 4 0 0 4 4 4 2 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGC28629.1 - 1.7e-09 37.9 0.9 0.01 16.1 0.0 4.7 4 1 0 4 4 4 2 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EGC28629.1 - 0.00034 20.5 0.1 0.48 10.5 0.0 3.3 3 1 0 3 3 3 2 CarboxypepD_reg-like domain bMG3 PF11974.8 EGC28629.1 - 0.11 12.5 0.0 3.8 7.6 0.0 2.7 3 0 0 3 3 3 0 Bacterial alpha-2-macroglobulin MG3 domain Big_1 PF02369.16 EGC28629.1 - 0.66 10.0 0.0 0.66 10.0 0.0 4.9 6 0 0 6 6 6 0 Bacterial Ig-like domain (group 1) SCO1-SenC PF02630.14 EGC28631.1 - 3.8e-49 166.0 0.0 8.1e-49 165.0 0.0 1.6 1 0 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGC28631.1 - 0.00033 20.9 1.7 0.00077 19.8 0.0 2.5 3 1 0 3 3 3 1 Thioredoxin-like AhpC-TSA PF00578.21 EGC28631.1 - 0.00036 20.4 0.0 0.0011 18.9 0.0 1.9 1 1 0 1 1 1 1 AhpC/TSA family Spt20 PF12090.8 EGC28631.1 - 0.0041 16.8 13.0 0.0058 16.3 13.0 1.2 1 0 0 1 1 1 1 Spt20 family ECM1 PF05782.11 EGC28631.1 - 0.025 13.6 0.8 0.031 13.2 0.8 1.1 1 0 0 1 1 1 0 Extracellular matrix protein 1 (ECM1) Presenilin PF01080.17 EGC28631.1 - 0.042 12.6 5.3 0.059 12.1 5.3 1.1 1 0 0 1 1 1 0 Presenilin EOS1 PF12326.8 EGC28631.1 - 0.1 12.5 4.5 0.15 12.0 4.5 1.2 1 0 0 1 1 1 0 N-glycosylation protein Roughex PF06020.11 EGC28631.1 - 0.12 11.4 2.2 0.17 10.9 2.2 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Connexin PF00029.19 EGC28631.1 - 0.15 11.8 2.3 0.23 11.2 2.3 1.2 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 EGC28631.1 - 0.17 10.6 5.9 0.25 10.1 5.9 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF4175 PF13779.6 EGC28631.1 - 1.2 7.0 6.7 1.5 6.6 6.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Menin PF05053.13 EGC28631.1 - 3.9 5.7 8.3 5.4 5.3 8.3 1.1 1 0 0 1 1 1 0 Menin MMU163 PF17119.5 EGC28631.1 - 4.2 6.4 8.2 3.1 6.9 6.8 1.4 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis Conotoxin PF02950.17 EGC28631.1 - 5.1 8.2 5.1 13 6.9 5.1 1.6 1 0 0 1 1 1 0 Conotoxin ALMT PF11744.8 EGC28631.1 - 8.6 5.1 7.9 15 4.3 7.9 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5438 PF17506.2 EGC28632.1 - 0.0085 16.4 2.2 0.22 11.9 0.2 2.4 2 0 0 2 2 2 2 Family of unknown function (DUF5438) Secretin_N_2 PF07655.13 EGC28632.1 - 0.8 10.3 16.6 6.4 7.4 12.5 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Arf PF00025.21 EGC28633.1 - 1.3e-61 207.0 1.4 3.7e-59 199.1 1.4 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC28633.1 - 2.1e-12 47.3 0.1 3.2e-12 46.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGC28633.1 - 3.4e-11 42.9 2.3 3.9e-06 26.3 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGC28633.1 - 2.8e-09 36.8 0.0 7.3e-08 32.2 0.1 2.0 1 1 1 2 2 2 1 Ras family Gtr1_RagA PF04670.12 EGC28633.1 - 3.8e-08 33.0 0.0 5.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGC28633.1 - 2e-06 27.4 0.0 5.3e-06 26.0 0.0 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC28633.1 - 9.7e-06 25.7 0.0 1.3e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase TniB PF05621.11 EGC28633.1 - 0.015 14.7 0.1 0.02 14.3 0.1 1.2 1 0 0 1 1 1 0 Bacterial TniB protein FeoB_N PF02421.18 EGC28633.1 - 0.034 13.7 0.2 0.16 11.5 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B RAB3GAP2_N PF14655.6 EGC28634.1 - 1.3e-131 439.7 0.3 1.7e-131 439.3 0.3 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus PIP5K PF01504.18 EGC28634.1 - 0.0087 15.3 0.3 0.0087 15.3 0.3 2.0 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase CIAPIN1 PF05093.13 EGC28634.1 - 0.66 10.5 3.9 6.2 7.4 0.3 2.5 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DUF4834 PF16118.5 EGC28634.1 - 7 7.7 13.5 0.87 10.6 1.1 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) eIF-6 PF01912.18 EGC28635.1 - 0.011 15.2 0.0 0.027 13.8 0.0 1.6 1 0 0 1 1 1 0 eIF-6 family GvpK PF05121.12 EGC28635.1 - 0.12 12.4 0.0 21 5.2 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K DNA_pol_A_exo1 PF01612.20 EGC28635.1 - 0.13 11.9 2.1 0.19 11.4 0.4 2.2 1 1 1 2 2 2 0 3'-5' exonuclease DUF3994 PF13159.6 EGC28635.1 - 0.24 12.0 3.5 0.17 12.5 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3994) Syntaxin-6_N PF09177.11 EGC28635.1 - 0.38 11.3 3.8 0.3 11.7 2.0 1.8 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Phosphodiest PF01663.22 EGC28636.1 - 4.8e-07 29.7 0.0 9.3e-07 28.7 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r PF07850.14 EGC28636.1 - 0.004 17.7 0.2 0.015 15.9 0.2 2.0 1 0 0 1 1 1 1 Renin receptor-like protein YejG PF13989.6 EGC28636.1 - 0.052 14.0 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 YejG-like protein RRM_1 PF00076.22 EGC28637.1 - 5.4e-14 51.8 0.4 1.4e-13 50.4 0.1 2.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CENP-I PF07778.11 EGC28638.1 - 1.9e-22 79.7 20.9 1.3e-12 47.2 5.1 3.3 2 1 2 4 4 4 2 Mis6 DUF1322 PF07032.11 EGC28638.1 - 0.033 14.7 6.0 0.047 14.2 0.8 3.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1322) DSPc PF00782.20 EGC28639.1 - 4.7e-34 117.1 0.2 4.7e-34 117.1 0.2 4.1 4 1 1 5 5 5 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC28639.1 - 1.1e-05 25.1 0.2 1.1e-05 25.1 0.2 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC28639.1 - 0.032 14.4 1.9 0.036 14.2 0.0 2.1 3 0 0 3 3 3 0 Inositol hexakisphosphate SUIM_assoc PF16619.5 EGC28639.1 - 2 8.5 11.1 0.29 11.2 3.3 3.0 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 NTP_transferase PF00483.23 EGC28640.1 - 8.7e-30 104.1 0.0 1.2e-29 103.7 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.7 EGC28640.1 - 1.5e-05 25.4 0.0 2.1e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.24 EGC28640.1 - 2.2e-05 24.0 3.8 3.9e-05 23.2 1.5 2.7 2 1 0 2 2 2 1 Bacterial transferase hexapeptide (six repeats) IspD PF01128.19 EGC28640.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTP_transf_3 PF02348.19 EGC28640.1 - 0.13 12.1 0.1 0.26 11.2 0.1 1.4 1 0 0 1 1 1 0 Cytidylyltransferase ATP-synt_F PF01990.17 EGC28641.1 - 1.8e-32 111.5 0.7 2.2e-32 111.3 0.7 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit UPF0183 PF03676.14 EGC28642.1 - 2.1e-99 333.5 10.4 1e-96 324.6 10.4 2.7 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0183) HTH_3 PF01381.22 EGC28642.1 - 0.13 12.3 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Pyridoxal_deC PF00282.19 EGC28643.1 - 2.9e-77 259.9 0.0 3.6e-77 259.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain 2OG-FeII_Oxy_3 PF13640.6 EGC28644.1 - 2.9e-11 44.1 0.0 5.1e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EGC28644.1 - 1.3e-06 27.8 0.1 1.5e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Poxvirus C4/C10 protein PhyH PF05721.13 EGC28644.1 - 0.013 15.7 0.0 1.4 9.2 0.0 2.4 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGC28644.1 - 0.088 13.2 0.0 0.27 11.7 0.0 1.9 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase zf-RING_2 PF13639.6 EGC28645.1 - 1.5e-10 41.2 12.8 2.8e-10 40.3 12.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC28645.1 - 6.4e-07 29.1 12.4 1.3e-06 28.2 12.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC28645.1 - 9.7e-07 28.6 9.1 1.6e-06 27.9 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC28645.1 - 1.8e-06 28.1 8.2 5.1e-06 26.7 8.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC28645.1 - 2.9e-06 27.1 14.4 6.5e-06 25.9 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC28645.1 - 0.00017 21.7 21.0 0.00017 21.7 21.0 2.0 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC28645.1 - 0.00063 19.6 13.2 0.00063 19.6 13.2 1.8 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC28645.1 - 0.0026 17.6 7.5 0.0063 16.3 7.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC28645.1 - 0.0041 17.2 3.8 0.0086 16.1 3.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC28645.1 - 0.0065 16.6 5.4 0.014 15.5 5.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EGC28645.1 - 0.026 14.5 6.7 0.026 14.5 6.7 1.9 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC28645.1 - 0.1 12.8 13.6 0.26 11.5 13.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC28645.1 - 0.54 10.1 9.0 1 9.2 9.0 1.5 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC28645.1 - 0.98 9.1 9.5 1.7 8.3 9.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MCD PF05292.11 EGC28645.1 - 3.9 7.0 7.0 0.28 10.7 0.7 2.1 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain DUF1272 PF06906.11 EGC28645.1 - 6.1 7.0 9.2 13 5.9 9.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rep_fac_C PF08542.11 EGC28646.1 - 5e-17 62.1 0.1 1.3e-16 60.8 0.1 1.7 2 0 0 2 2 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGC28646.1 - 4.7e-14 52.9 0.0 8.1e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGC28646.1 - 5.8e-14 52.2 0.0 2.9e-12 46.7 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGC28646.1 - 5.3e-09 36.3 0.0 1.6e-08 34.7 0.0 1.8 2 1 0 2 2 2 1 Rad17 P-loop domain AAA_assoc_2 PF16193.5 EGC28646.1 - 8.7e-05 22.8 0.0 0.0019 18.5 0.0 2.5 2 0 0 2 2 2 1 AAA C-terminal domain AAA_11 PF13086.6 EGC28646.1 - 9.3e-05 22.3 0.0 0.00021 21.1 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC28646.1 - 9.9e-05 22.8 0.1 0.0017 18.7 0.1 2.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.6 EGC28646.1 - 0.00019 21.2 0.0 0.00044 20.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC28646.1 - 0.0002 21.2 0.0 0.00049 19.9 0.0 1.6 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGC28646.1 - 0.00028 20.4 0.0 0.0058 16.0 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI RuvB_N PF05496.12 EGC28646.1 - 0.00041 20.1 0.0 0.00074 19.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC28646.1 - 0.00096 19.4 0.1 0.027 14.7 0.1 2.5 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGC28646.1 - 0.0012 18.9 0.0 0.057 13.4 0.0 2.3 1 1 1 2 2 2 1 Type III restriction enzyme, res subunit PhoH PF02562.16 EGC28646.1 - 0.021 14.3 0.0 0.89 9.0 0.0 2.4 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.14 EGC28646.1 - 0.023 14.7 0.2 0.12 12.4 0.2 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DEAD PF00270.29 EGC28646.1 - 0.024 14.4 0.1 0.28 10.9 0.0 2.2 1 1 1 2 2 2 0 DEAD/DEAH box helicase AAA_19 PF13245.6 EGC28646.1 - 0.029 14.7 0.3 0.31 11.4 0.3 2.2 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGC28646.1 - 0.054 13.0 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGC28646.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.6 EGC28646.1 - 0.22 12.0 2.1 0.76 10.2 2.1 1.9 1 1 0 1 1 1 0 AAA domain SDA1 PF05285.12 EGC28647.1 - 0.018 14.5 13.0 0.024 14.1 13.0 1.2 1 0 0 1 1 1 0 SDA1 V_ATPase_I PF01496.19 EGC28647.1 - 0.084 10.8 5.2 0.11 10.4 5.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nop14 PF04147.12 EGC28647.1 - 0.18 10.0 22.8 0.25 9.5 22.8 1.1 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.13 EGC28647.1 - 0.31 9.1 16.1 0.48 8.5 16.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi BUD22 PF09073.10 EGC28647.1 - 1.3 8.3 19.2 1.9 7.8 19.2 1.1 1 0 0 1 1 1 0 BUD22 Vfa1 PF08432.10 EGC28647.1 - 1.7 8.9 14.3 2.8 8.2 14.3 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 CDC45 PF02724.14 EGC28647.1 - 2.8 6.1 14.0 4.9 5.3 14.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Histone PF00125.24 EGC28651.1 - 0.00029 21.2 0.3 0.018 15.4 0.0 2.3 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EGC28651.1 - 0.44 10.6 3.3 2.2 8.4 0.1 2.6 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit Abhydrolase_1 PF00561.20 EGC28652.1 - 0.0008 19.1 0.1 0.0051 16.5 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC28652.1 - 0.0018 17.6 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ser_hydrolase PF06821.13 EGC28652.1 - 0.014 15.3 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.12 EGC28652.1 - 0.053 13.0 0.0 0.086 12.3 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) DUF3089 PF11288.8 EGC28652.1 - 0.082 12.4 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Lipase_3 PF01764.25 EGC28652.1 - 0.092 12.6 0.0 0.21 11.5 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Sec7 PF01369.20 EGC28653.1 - 2.7e-56 190.2 3.3 2.7e-56 190.2 3.3 2.7 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGC28653.1 - 2.2e-32 112.1 3.6 2.2e-32 112.1 3.6 5.5 7 0 0 7 7 7 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGC28653.1 - 9.3e-26 89.5 13.1 2.3e-25 88.3 0.2 5.7 7 0 0 7 7 7 2 Domain of unknown function (DUF1981) HEAT PF02985.22 EGC28653.1 - 0.024 14.9 0.6 2.4e+02 2.4 0.0 5.2 5 0 0 5 5 5 0 HEAT repeat CH PF00307.31 EGC28654.1 - 1.3e-34 118.6 27.7 6.8e-15 55.2 0.0 6.7 6 0 0 6 6 6 4 Calponin homology (CH) domain Urm1 PF09138.11 EGC28654.1 - 0.0081 16.5 2.9 13 6.3 0.0 4.5 3 1 0 3 3 3 1 Urm1 (Ubiquitin related modifier) CAMSAP_CH PF11971.8 EGC28654.1 - 0.024 14.5 11.6 0.84 9.5 0.0 5.0 6 0 0 6 6 6 0 CAMSAP CH domain zf-C3HC4 PF00097.25 EGC28655.1 - 1.2e-08 34.7 12.4 3.2e-08 33.3 12.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC28655.1 - 2.9e-08 33.5 7.9 5e-08 32.7 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC28655.1 - 1.3e-07 31.3 12.3 2.6e-07 30.4 12.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC28655.1 - 2.3e-06 27.8 11.0 5e-06 26.7 11.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC28655.1 - 0.00031 20.7 10.8 0.00082 19.3 10.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC28655.1 - 0.0006 19.7 11.6 0.0025 17.7 11.7 2.0 1 1 1 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC28655.1 - 0.0015 18.3 8.7 0.0054 16.6 8.8 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC28655.1 - 0.017 15.2 11.7 0.042 14.0 11.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGC28655.1 - 0.035 14.3 7.9 0.13 12.5 6.7 2.5 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EGC28655.1 - 0.27 11.5 8.9 1.1 9.7 8.9 2.1 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC28655.1 - 0.37 10.7 2.4 0.76 9.7 2.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mucin PF01456.17 EGC28655.1 - 0.7 9.9 16.9 1.5 8.8 16.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein CemA PF03040.14 EGC28655.1 - 3.5 7.5 6.5 11 5.9 6.5 1.8 1 0 0 1 1 1 0 CemA family Arm PF00514.23 EGC28657.1 - 1.1e-14 53.9 0.2 0.014 15.4 0.0 7.0 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.9 EGC28657.1 - 2.7e-13 49.8 1.8 0.018 15.0 0.4 6.1 1 1 6 7 7 7 5 Spinocerebellar ataxia type 10 protein domain HEAT_EZ PF13513.6 EGC28657.1 - 0.0044 17.5 0.3 16 6.1 0.1 3.8 3 1 1 4 4 4 1 HEAT-like repeat F-box-like PF12937.7 EGC28657.1 - 0.012 15.4 0.6 0.026 14.4 0.6 1.5 1 0 0 1 1 1 0 F-box-like SR-25 PF10500.9 EGC28658.1 - 1.5 8.4 20.5 0.35 10.4 7.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF737 PF05300.11 EGC28658.1 - 4.6 7.5 10.2 6.2 7.1 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF737) E1-E2_ATPase PF00122.20 EGC28659.1 - 2.1e-43 147.9 0.2 2.1e-43 147.9 0.2 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGC28659.1 - 9.8e-39 132.9 7.1 9.8e-39 132.9 7.1 3.3 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGC28659.1 - 1.5e-20 74.4 0.2 2.2e-07 31.4 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGC28659.1 - 4e-13 49.3 0.0 1.3e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGC28659.1 - 6.7e-13 48.1 0.0 6.2e-12 45.0 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGC28659.1 - 0.0024 17.7 0.0 0.008 15.9 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase FtsK_4TM PF13491.6 EGC28659.1 - 2.8 7.6 9.0 0.6 9.8 0.8 2.8 3 0 0 3 3 3 0 4TM region of DNA translocase FtsK/SpoIIIE UPF0182 PF03699.13 EGC28659.1 - 8.1 4.4 7.6 4.7 5.2 0.0 2.9 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0182) SF3b1 PF08920.10 EGC28660.1 - 5.9e-26 91.3 1.6 5.9e-26 91.3 1.6 2.6 1 1 1 2 2 2 1 Splicing factor 3B subunit 1 HEAT PF02985.22 EGC28660.1 - 4.2e-15 54.6 4.4 0.043 14.1 0.0 9.1 9 0 0 9 9 9 3 HEAT repeat HEAT_2 PF13646.6 EGC28660.1 - 3.7e-13 49.7 2.0 0.033 14.6 0.0 7.8 5 2 3 8 8 8 3 HEAT repeats HEAT_EZ PF13513.6 EGC28660.1 - 2.8e-11 43.6 0.0 0.23 12.0 0.0 7.7 8 0 0 8 8 8 1 HEAT-like repeat Adaptin_N PF01602.20 EGC28660.1 - 5.2e-06 25.3 1.1 0.002 16.7 0.0 3.4 2 2 0 2 2 2 1 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGC28660.1 - 1.2e-05 25.8 3.4 4.2 8.0 0.0 5.7 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region Cnd1 PF12717.7 EGC28660.1 - 5.2e-05 23.3 14.0 0.33 11.0 0.0 6.5 7 1 1 9 9 9 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.8 EGC28660.1 - 9.1e-05 22.1 0.3 2.2 7.8 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal CTD PF12815.7 EGC28660.1 - 0.0012 19.3 3.1 0.0032 18.0 3.1 1.7 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 NUC173 PF08161.12 EGC28660.1 - 0.0023 17.6 1.4 2.4 7.8 0.0 5.3 4 2 2 6 6 6 1 NUC173 domain Dopey_N PF04118.14 EGC28660.1 - 0.0039 16.3 2.1 8.5 5.4 0.1 4.0 3 1 1 5 5 5 2 Dopey, N-terminal TAF6_C PF07571.13 EGC28660.1 - 0.0069 16.7 0.0 0.18 12.2 0.0 3.3 2 1 0 2 2 2 1 TAF6 C-terminal HEAT repeat domain Arm PF00514.23 EGC28660.1 - 0.021 14.8 0.0 32 4.8 0.0 4.3 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RTP1_C1 PF10363.9 EGC28660.1 - 0.028 14.6 1.9 5.5 7.2 0.1 4.3 4 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 UNC45-central PF11701.8 EGC28660.1 - 0.098 12.6 0.1 0.42 10.6 0.1 2.1 1 0 0 1 1 1 0 Myosin-binding striated muscle assembly central HEAT PF02985.22 EGC28661.1 - 4.3e-29 98.1 1.9 0.00018 21.5 0.0 9.4 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.6 EGC28661.1 - 1.1e-17 64.2 0.0 0.00019 21.8 0.1 5.9 2 2 6 8 8 8 7 HEAT repeats Vac14_Fab1_bd PF12755.7 EGC28661.1 - 1.6e-07 31.8 0.2 0.00011 22.7 0.0 4.1 3 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGC28661.1 - 6.4e-06 26.6 0.2 0.22 12.1 0.0 4.7 5 1 0 5 5 5 1 HEAT-like repeat Cnd1 PF12717.7 EGC28661.1 - 1.4e-05 25.2 0.2 0.084 12.9 0.2 3.7 1 1 2 3 3 3 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGC28661.1 - 0.00069 18.3 3.3 0.088 11.4 0.5 3.3 2 1 1 3 3 3 2 Adaptin N terminal region DUF3730 PF12530.8 EGC28661.1 - 0.013 15.0 0.5 0.06 12.9 0.2 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3730) DNA_alkylation PF08713.11 EGC28661.1 - 0.014 15.2 0.0 0.56 9.9 0.1 3.3 1 1 2 3 3 3 0 DNA alkylation repair enzyme Wap1 PF16997.5 EGC28661.1 - 0.062 12.4 1.8 0.14 11.3 0.3 2.1 2 1 0 2 2 2 0 Wap1 domain CoA_trans PF01144.23 EGC28663.1 - 9.2e-119 394.6 0.6 5.4e-77 258.0 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase Haem_oxygenas_2 PF14518.6 EGC28664.1 - 0.0023 17.7 0.1 0.0031 17.3 0.1 1.1 1 0 0 1 1 1 1 Iron-containing redox enzyme Cyclin PF08613.11 EGC28666.1 - 3.5e-36 125.0 0.2 3.5e-36 125.0 0.2 2.8 2 1 1 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGC28666.1 - 1.9e-08 34.1 0.0 4.7e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain GATase_4 PF13230.6 EGC28667.1 - 2e-13 49.9 0.0 3.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II GATase_6 PF13522.6 EGC28667.1 - 1e-12 48.4 0.0 2.1e-12 47.4 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase domain DJ-1_PfpI PF01965.24 EGC28669.1 - 2.8e-39 134.6 0.0 3.3e-39 134.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family GATase PF00117.28 EGC28669.1 - 0.00062 19.6 0.2 0.0011 18.8 0.1 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.6 EGC28669.1 - 0.026 13.6 0.0 0.036 13.2 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.14 EGC28669.1 - 0.026 14.1 0.0 0.037 13.6 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pkinase PF00069.25 EGC28670.1 - 2.4e-57 194.3 0.0 2.4e-57 194.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28670.1 - 1.4e-16 60.6 0.0 2.5e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC28670.1 - 0.022 14.7 0.0 0.081 12.8 0.0 1.8 1 1 0 1 1 1 0 Phosphotransferase enzyme family DIE2_ALG10 PF04922.12 EGC28671.1 - 1.2e-56 192.7 20.3 2.1e-56 191.9 20.3 1.4 1 1 0 1 1 1 1 DIE2/ALG10 family CSG2 PF16965.5 EGC28671.1 - 7.3e-06 25.2 2.6 1.2e-05 24.4 2.6 1.3 1 0 0 1 1 1 1 Ceramide synthase regulator Peroxin-13_N PF04088.13 EGC28671.1 - 0.0015 18.9 0.5 0.0037 17.5 0.5 1.7 1 0 0 1 1 1 1 Peroxin 13, N-terminal region CLN3 PF02487.17 EGC28671.1 - 0.0019 17.3 0.1 0.0027 16.8 0.1 1.2 1 0 0 1 1 1 1 CLN3 protein Connexin PF00029.19 EGC28671.1 - 0.0027 17.5 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Connexin LRRC37AB_C PF14914.6 EGC28671.1 - 0.0032 17.4 1.9 0.0059 16.5 1.9 1.3 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain HCO3_cotransp PF00955.21 EGC28671.1 - 0.015 14.1 4.1 0.027 13.3 4.1 1.4 1 0 0 1 1 1 0 HCO3- transporter family DUF3611 PF12263.8 EGC28671.1 - 0.072 13.0 1.4 7.1 6.5 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3611) Tim54 PF11711.8 EGC28671.1 - 0.1 11.4 0.0 0.13 11.0 0.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GCD14 PF08704.10 EGC28671.1 - 0.91 9.2 2.7 1.4 8.6 2.7 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Gti1_Pac2 PF09729.9 EGC28671.1 - 1.6 8.8 8.5 2.8 8.0 8.5 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family GST_C_3 PF14497.6 EGC28673.1 - 1.7e-10 40.9 0.5 3.5e-10 39.9 0.5 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC28673.1 - 2.5e-07 30.8 0.1 4.5e-07 30.0 0.1 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC28673.1 - 0.078 13.3 1.2 0.35 11.2 0.2 2.2 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC28674.1 - 4.4e-15 55.7 0.0 7.1e-15 55.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC28674.1 - 2.1e-10 40.8 0.1 3.5e-10 40.1 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC28674.1 - 6.7e-09 35.9 0.0 1.3e-08 34.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC28674.1 - 2.9e-06 27.2 0.0 5.1e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC28674.1 - 2.7e-05 24.5 0.0 4.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC28674.1 - 0.0088 15.8 0.1 0.025 14.3 0.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC28674.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain QRPTase_C PF01729.19 EGC28675.1 - 1.3e-57 194.3 0.3 1.6e-57 193.9 0.3 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.16 EGC28675.1 - 2.1e-16 59.8 0.0 7.6e-16 57.9 0.0 2.0 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.19 EGC28675.1 - 0.0017 17.7 0.4 0.071 12.5 0.0 2.3 1 1 1 2 2 2 2 Ribulose-phosphate 3 epimerase family TBP-binding PF09247.11 EGC28676.1 - 0.074 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 TATA box-binding protein binding DAGK_cat PF00781.24 EGC28677.1 - 1.9e-29 101.9 0.1 4.4e-29 100.7 0.1 1.7 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.21 EGC28677.1 - 0.0013 18.0 0.0 0.0028 16.9 0.0 1.5 1 0 0 1 1 1 1 ATP-NAD kinase Folate_carrier PF01770.18 EGC28680.1 - 5.6e-24 84.6 54.3 1.5e-13 50.3 10.5 5.1 2 2 2 4 4 4 3 Reduced folate carrier MFS_1 PF07690.16 EGC28680.1 - 0.0035 16.3 29.3 0.94 8.3 29.1 3.1 1 1 1 2 2 2 1 Major Facilitator Superfamily Nudc_N PF14050.6 EGC28680.1 - 1.1 9.3 7.6 1.2 9.1 0.1 3.5 3 1 1 4 4 4 0 N-terminal conserved domain of Nudc. CBS PF00571.28 EGC28681.1 - 6.8e-26 90.5 4.7 8.8e-10 38.9 0.0 4.4 4 0 0 4 4 4 4 CBS domain PH_4 PF15404.6 EGC28681.1 - 3.3 7.5 6.9 5.1 6.8 3.2 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Costars PF14705.6 EGC28682.1 - 3.4e-28 97.6 1.2 3.8e-28 97.5 1.2 1.0 1 0 0 1 1 1 1 Costars Costars PF14705.6 EGC28683.1 - 3.4e-28 97.6 1.2 3.8e-28 97.5 1.2 1.0 1 0 0 1 1 1 1 Costars Pribosyltran_N PF13793.6 EGC28684.1 - 1.1e-43 147.9 0.5 4.1e-43 146.0 0.0 2.0 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGC28684.1 - 8.6e-34 117.2 3.9 7.9e-32 110.8 3.0 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGC28684.1 - 8.4e-13 48.1 0.5 9.8e-12 44.7 0.3 2.3 2 1 0 2 2 2 1 Phosphoribosyl transferase domain AF2331-like PF14556.6 EGC28684.1 - 0.12 12.9 3.5 3 8.5 0.0 2.7 3 0 0 3 3 3 0 AF2331-like HD PF01966.22 EGC28685.1 - 7.3e-16 58.5 1.3 1.3e-15 57.7 0.5 1.9 2 0 0 2 2 2 1 HD domain PDEase_I PF00233.19 EGC28685.1 - 0.033 13.9 0.0 0.093 12.4 0.0 1.7 1 0 0 1 1 1 0 3'5'-cyclic nucleotide phosphodiesterase Ras PF00071.22 EGC28686.1 - 4.3e-45 153.2 0.0 5e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28686.1 - 6.1e-33 113.6 0.0 8e-33 113.2 0.0 1.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC28686.1 - 6.3e-13 48.6 0.0 7.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EGC28686.1 - 0.00045 20.1 0.0 0.00062 19.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGC28686.1 - 0.00097 19.2 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC28686.1 - 0.011 15.1 0.0 0.014 14.7 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC28686.1 - 0.023 14.2 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain Neuropeptide_S PF14993.6 EGC28686.1 - 0.13 12.1 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 Neuropeptide S precursor protein RsgA_GTPase PF03193.16 EGC28686.1 - 0.13 12.1 0.0 4.3 7.2 0.0 2.4 2 1 1 3 3 3 0 RsgA GTPase VASt PF16016.5 EGC28687.1 - 1.2e-26 93.9 2.5 1.2e-26 93.9 2.5 2.6 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGC28687.1 - 6.2e-17 61.5 0.3 1.5e-16 60.3 0.3 1.6 1 0 0 1 1 1 1 GRAM domain Adeno_E3 PF06040.11 EGC28687.1 - 0.081 13.1 0.2 0.081 13.1 0.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein adh_short PF00106.25 EGC28688.1 - 6.4e-40 136.7 0.1 8.8e-40 136.2 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28688.1 - 1.1e-28 100.4 0.0 1.4e-28 100.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28688.1 - 4e-08 33.4 0.0 5.8e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC28688.1 - 1.9e-05 24.3 0.1 3.1e-05 23.6 0.1 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC28688.1 - 0.00041 19.9 0.1 0.00058 19.4 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGC28688.1 - 0.00076 18.9 0.0 0.00094 18.6 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) 3Beta_HSD PF01073.19 EGC28688.1 - 0.0011 18.0 0.5 0.0019 17.2 0.5 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGC28688.1 - 0.0027 16.9 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC28688.1 - 0.03 13.5 0.0 0.044 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein DUF953 PF06110.11 EGC28689.1 - 1.8e-09 37.2 0.4 2.1e-09 37.0 0.4 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.20 EGC28689.1 - 0.004 17.1 0.7 0.0069 16.4 0.7 1.4 1 1 0 1 1 1 1 Thioredoxin DUF695 PF05117.12 EGC28689.1 - 0.017 15.3 0.0 0.021 15.0 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF695) Gelsolin PF00626.22 EGC28690.1 - 2.1e-47 158.9 3.8 2.5e-12 46.5 0.0 5.9 5 0 0 5 5 5 5 Gelsolin repeat PBD PF00786.28 EGC28690.1 - 1e-17 64.2 0.1 5.9e-09 36.2 0.1 3.3 2 0 0 2 2 2 2 P21-Rho-binding domain eIF_4EBP PF05456.11 EGC28691.1 - 1.2e-25 89.7 4.7 1.3e-25 89.6 4.7 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DSPc PF00782.20 EGC28692.1 - 4.2e-08 33.1 0.0 5.5e-08 32.7 0.0 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGC28692.1 - 1.6e-06 27.9 0.0 2.1e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.27 EGC28692.1 - 1.4e-05 24.8 0.0 1.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Cut8 PF08559.10 EGC28693.1 - 1.6e-36 126.2 9.2 1.6e-36 126.2 9.2 2.0 1 1 1 2 2 2 1 Cut8, nuclear proteasome tether protein CdiI_2 PF18593.1 EGC28693.1 - 0.027 15.1 0.7 0.072 13.7 0.1 2.0 2 0 0 2 2 2 0 CdiI immunity protein Menin PF05053.13 EGC28693.1 - 0.21 9.9 11.5 0.32 9.3 11.5 1.2 1 0 0 1 1 1 0 Menin Snf7 PF03357.21 EGC28693.1 - 0.55 9.8 7.1 8.2 6.0 0.1 2.5 2 0 0 2 2 2 0 Snf7 DUF2804 PF10974.8 EGC28694.1 - 1.7e-114 382.8 2.6 2e-114 382.5 2.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) DUF1410 PF07198.11 EGC28694.1 - 0.68 10.5 6.4 0.35 11.4 1.7 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1410) Myb_DNA-binding PF00249.31 EGC28696.1 - 3.4e-10 40.0 0.1 5.6e-10 39.3 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Shikimate_dh_N PF08501.11 EGC28696.1 - 1.7 9.0 4.9 1.3 9.3 0.1 3.2 3 0 0 3 3 3 0 Shikimate dehydrogenase substrate binding domain SLX9 PF15341.6 EGC28698.1 - 2.4e-19 70.0 16.8 2.4e-19 70.0 16.8 3.3 3 1 0 3 3 3 1 Ribosome biogenesis protein SLX9 NOA36 PF06524.12 EGC28698.1 - 0.33 10.2 10.4 0.032 13.6 6.0 1.6 2 0 0 2 2 2 0 NOA36 protein Aminotran_1_2 PF00155.21 EGC28699.1 - 8.6e-84 281.8 0.0 9.9e-84 281.6 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SKG6 PF08693.10 EGC28700.1 - 0.0013 18.1 0.8 0.0013 18.1 0.8 1.7 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.6 EGC28700.1 - 0.034 13.9 0.6 0.038 13.8 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) PhyH PF05721.13 EGC28701.1 - 6.3e-23 82.1 0.0 7.8e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HMG_box PF00505.19 EGC28702.1 - 2.2e-19 69.6 2.1 4.8e-19 68.6 2.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC28702.1 - 6.1e-16 58.8 3.2 1.3e-15 57.7 3.2 1.6 1 0 0 1 1 1 1 HMG-box domain SR-25 PF10500.9 EGC28702.1 - 0.17 11.5 24.9 0.2 11.3 14.2 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Tubulin PF00091.25 EGC28704.1 - 1.9e-36 126.1 1.4 4e-36 125.1 1.4 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EGC28704.1 - 6.2e-22 77.7 0.1 2.2e-21 75.9 0.0 2.0 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Tubulin_2 PF13809.6 EGC28704.1 - 3.7 6.6 7.2 2.1 7.4 1.2 2.9 1 1 1 2 2 2 0 Tubulin like Peptidase_M24 PF00557.24 EGC28705.1 - 3.2e-36 125.0 0.0 3.9e-36 124.7 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 Inhibitor_I53 PF11714.8 EGC28705.1 - 1.2 9.4 4.7 0.88 9.8 2.8 1.7 2 0 0 2 2 2 0 Thrombin inhibitor Madanin Coilin_N PF15862.5 EGC28705.1 - 3.4 7.5 5.4 11 5.8 5.4 1.7 2 0 0 2 2 2 0 Coilin N-terminus zf-DBF PF07535.12 EGC28707.1 - 9.9e-18 64.0 2.2 4.3e-17 61.9 2.2 2.2 1 0 0 1 1 1 1 DBF zinc finger SUIM_assoc PF16619.5 EGC28707.1 - 0.0049 16.9 5.9 0.0049 16.9 5.9 5.5 3 1 2 5 5 5 2 Unstructured region C-term to UIM in Ataxin3 DUF885 PF05960.11 EGC28708.1 - 6.1e-78 263.8 0.0 8.2e-78 263.3 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) Clavanin PF05452.11 EGC28709.1 - 0.25 11.5 1.9 0.85 9.9 1.9 2.0 1 0 0 1 1 1 0 Clavanin DUF4337 PF14235.6 EGC28711.1 - 0.022 14.9 1.9 0.026 14.7 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4634 PF15465.6 EGC28712.1 - 0.74 10.1 4.3 2.7 8.3 4.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) DUF5613 PF18467.1 EGC28715.1 - 0.029 14.8 0.0 0.031 14.7 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5613) STN PF07660.14 EGC28715.1 - 0.13 12.1 0.0 0.15 11.8 0.0 1.1 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain BTB PF00651.31 EGC28716.1 - 4.6e-21 75.1 5.0 4e-19 68.9 1.3 3.2 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.15 EGC28716.1 - 2.1e-11 43.8 3.0 1.5e-09 37.8 0.3 3.2 3 0 0 3 3 3 1 BTB And C-terminal Kelch F5_F8_type_C PF00754.25 EGC28716.1 - 0.016 15.4 0.0 0.078 13.1 0.0 2.2 2 0 0 2 2 2 0 F5/8 type C domain DUF3342 PF11822.8 EGC28716.1 - 0.14 12.4 3.3 0.5 10.6 0.8 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3342) MFS_1 PF07690.16 EGC28717.1 - 1.1e-08 34.4 42.2 0.00023 20.2 28.8 2.9 1 1 1 2 2 2 2 Major Facilitator Superfamily PET117 PF15786.5 EGC28718.1 - 4.1e-12 46.2 0.0 4.7e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 PET assembly of cytochrome c oxidase, mitochondrial CLN3 PF02487.17 EGC28718.1 - 0.14 11.2 0.4 0.14 11.2 0.4 1.0 1 0 0 1 1 1 0 CLN3 protein P5-ATPase PF12409.8 EGC28718.1 - 0.8 9.8 4.4 0.66 10.1 3.6 1.2 1 1 0 1 1 1 0 P5-type ATPase cation transporter Formyl_trans_N PF00551.19 EGC28719.1 - 6.9e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGC28719.1 - 0.0032 17.7 0.1 2.6 8.3 0.0 2.6 3 0 0 3 3 3 2 Formyl transferase, C-terminal domain DUF2202 PF09968.9 EGC28719.1 - 0.02 14.7 0.3 0.037 13.9 0.3 1.4 1 0 0 1 1 1 0 Uncharacterized protein domain (DUF2202) PA14 PF07691.12 EGC28721.1 - 4e-05 23.5 0.0 9.1e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 PA14 domain Menin PF05053.13 EGC28721.1 - 0.31 9.3 3.2 0.46 8.8 3.2 1.2 1 0 0 1 1 1 0 Menin Ras PF00071.22 EGC28722.1 - 2.3e-31 108.6 4.2 1.2e-20 73.7 0.0 3.2 2 1 0 2 2 2 2 Ras family Roc PF08477.13 EGC28722.1 - 3.3e-18 66.1 0.5 1.4e-09 38.2 0.0 3.8 2 2 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase EF_assoc_1 PF08355.12 EGC28722.1 - 2.9e-15 55.6 0.0 5.8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.12 EGC28722.1 - 1.6e-14 53.6 1.5 3.5e-12 46.1 0.1 3.6 3 1 0 3 3 2 1 EF hand associated EF-hand_1 PF00036.32 EGC28722.1 - 3.3e-09 35.6 0.2 0.0024 17.3 0.1 3.3 2 0 0 2 2 2 2 EF hand MMR_HSR1 PF01926.23 EGC28722.1 - 3.8e-09 36.6 1.5 5.4e-05 23.2 0.1 3.2 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_6 PF13405.6 EGC28722.1 - 5.3e-08 32.2 4.7 0.00065 19.4 0.0 3.8 4 0 0 4 4 3 2 EF-hand domain GTP_EFTU PF00009.27 EGC28722.1 - 4.2e-07 29.7 0.2 0.0034 16.9 0.0 3.9 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain EF-hand_7 PF13499.6 EGC28722.1 - 1.1e-06 28.9 5.5 0.00013 22.3 0.1 3.6 4 1 0 4 4 2 2 EF-hand domain pair ATPase_2 PF01637.18 EGC28722.1 - 3.8e-06 27.0 1.3 0.052 13.4 0.1 2.8 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea Septin PF00735.18 EGC28722.1 - 1.4e-05 24.5 0.3 0.054 12.8 0.0 3.1 3 0 0 3 3 3 2 Septin AAA_24 PF13479.6 EGC28722.1 - 1.5e-05 24.8 0.2 0.12 12.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain EF-hand_5 PF13202.6 EGC28722.1 - 6.3e-05 22.3 0.5 0.4 10.3 0.0 2.9 2 0 0 2 2 2 2 EF hand Arf PF00025.21 EGC28722.1 - 6.9e-05 22.4 0.0 0.0079 15.7 0.1 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGC28722.1 - 0.00015 21.8 1.1 1.8 8.4 0.1 3.7 3 1 1 4 4 4 1 RsgA GTPase Dynamin_N PF00350.23 EGC28722.1 - 0.00027 21.0 0.1 2.4 8.2 0.0 3.4 3 0 0 3 3 3 2 Dynamin family FeoB_N PF02421.18 EGC28722.1 - 0.00051 19.6 0.6 0.052 13.1 0.1 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.22 EGC28722.1 - 0.0011 19.3 0.5 6.2 7.3 0.0 3.6 3 1 0 3 3 3 1 RNA helicase TniB PF05621.11 EGC28722.1 - 0.002 17.6 0.2 0.82 9.1 0.0 3.1 3 0 0 3 3 2 1 Bacterial TniB protein EF-hand_10 PF14788.6 EGC28722.1 - 0.0024 17.7 1.9 0.0048 16.7 0.2 2.4 3 0 0 3 3 2 1 EF hand AAA_14 PF13173.6 EGC28722.1 - 0.0039 17.2 0.2 13 5.8 0.0 3.6 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.6 EGC28722.1 - 0.017 15.4 0.1 14 6.0 0.0 3.4 3 1 0 3 3 3 0 AAA domain EF-hand_8 PF13833.6 EGC28722.1 - 0.024 14.5 0.8 4.3 7.3 0.1 3.4 3 0 0 3 3 3 0 EF-hand domain pair AAA PF00004.29 EGC28722.1 - 0.024 15.1 0.1 9.2 6.7 0.1 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SPARC_Ca_bdg PF10591.9 EGC28722.1 - 0.027 14.8 1.0 0.68 10.3 0.1 2.8 3 0 0 3 3 2 0 Secreted protein acidic and rich in cysteine Ca binding region MobB PF03205.14 EGC28722.1 - 0.087 12.7 0.1 2.2 8.2 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Ribo_biogen_C PF04034.13 EGC28723.1 - 5.1e-54 181.4 0.0 6.1e-54 181.1 0.0 1.1 1 0 0 1 1 1 1 Ribosome biogenesis protein, C-terminal RLI PF04068.15 EGC28723.1 - 6.3e-12 45.1 0.0 1.7e-11 43.7 0.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2034 PF10356.9 EGC28724.1 - 2.6e-07 30.3 0.4 0.00048 19.6 0.0 3.8 3 2 1 4 4 4 2 Protein of unknown function (DUF2034) FAD_binding_1 PF00667.20 EGC28725.1 - 2.2e-40 138.6 0.5 4.2e-40 137.7 0.5 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.21 EGC28725.1 - 4.9e-17 62.6 0.0 8.5e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGC28725.1 - 0.036 14.2 0.5 0.24 11.5 0.2 2.5 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Peptidase_S24 PF00717.23 EGC28725.1 - 0.15 12.1 0.2 0.5 10.4 0.1 1.9 1 1 1 2 2 2 0 Peptidase S24-like Vps52 PF04129.12 EGC28728.1 - 1.5e-05 23.9 0.0 1.9e-05 23.6 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family PIP5K PF01504.18 EGC28729.1 - 8.7e-70 235.1 8.1 8.7e-70 235.1 8.1 2.4 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase LAGLIDADG_WhiA PF14527.6 EGC28729.1 - 0.14 12.3 2.6 0.36 10.9 2.6 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain NEMP PF10225.9 EGC28729.1 - 9 5.9 8.5 7.6 6.1 5.4 2.2 2 1 0 2 2 2 0 NEMP family Macoilin PF09726.9 EGC28730.1 - 0.3 9.6 13.2 0.37 9.3 13.2 1.2 1 0 0 1 1 1 0 Macoilin family RhoGEF PF00621.20 EGC28731.1 - 1.1e-38 133.3 3.2 1.1e-38 133.3 3.2 3.1 3 1 1 4 4 4 1 RhoGEF domain PH PF00169.29 EGC28731.1 - 0.049 14.1 0.2 0.21 12.1 0.2 2.1 1 0 0 1 1 1 0 PH domain PilN_bio_d PF18222.1 EGC28732.1 - 0.032 14.6 0.0 0.05 14.0 0.0 1.3 1 0 0 1 1 1 0 PilN biogenesis protein dimerization domain SNF2_N PF00176.23 EGC28734.1 - 2.8e-67 226.9 0.6 4.6e-67 226.2 0.6 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC28734.1 - 1e-16 61.2 0.0 5.4e-16 58.9 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGC28734.1 - 1.5e-06 27.9 5.7 3e-06 27.0 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC28734.1 - 3.7e-05 23.5 8.9 8.4e-05 22.4 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC28734.1 - 9.9e-05 22.4 8.5 0.00024 21.2 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGC28734.1 - 0.00017 21.3 8.9 0.00038 20.2 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC28734.1 - 0.00034 20.6 8.5 0.00077 19.4 8.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger RBR PF17208.3 EGC28734.1 - 0.019 15.6 1.8 0.07 13.9 1.8 2.0 1 0 0 1 1 1 0 RNA binding Region zf-RING_2 PF13639.6 EGC28734.1 - 0.022 15.1 7.9 0.064 13.6 7.9 1.9 1 0 0 1 1 1 0 Ring finger domain zf-RING_6 PF14835.6 EGC28734.1 - 0.073 13.0 3.0 0.16 11.8 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_5 PF14634.6 EGC28734.1 - 0.11 12.4 8.6 0.26 11.3 8.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC28734.1 - 0.13 12.2 6.9 0.27 11.1 6.9 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC28734.1 - 0.16 12.1 3.5 0.42 10.8 3.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC28734.1 - 1.6 8.6 5.8 3.8 7.4 5.8 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Mucin PF01456.17 EGC28734.1 - 3.2 7.7 16.3 3.7 7.5 3.9 3.3 3 0 0 3 3 3 0 Mucin-like glycoprotein SMN PF06003.12 EGC28735.1 - 1.2e-06 28.0 24.6 0.00027 20.3 11.1 2.4 1 1 1 2 2 2 2 Survival motor neuron protein (SMN) CCDC106 PF15794.5 EGC28735.1 - 5.5 6.6 18.1 0.25 11.0 8.2 2.2 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Ribosomal_S13 PF00416.22 EGC28736.1 - 1.2e-50 171.2 3.0 1.4e-50 170.9 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.11 EGC28736.1 - 0.034 12.9 0.0 0.035 12.9 0.0 1.1 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) PP28 PF10252.9 EGC28736.1 - 0.29 11.6 1.8 0.46 11.0 0.4 1.9 2 0 0 2 2 2 0 Casein kinase substrate phosphoprotein PP28 Transketolase_C PF02780.20 EGC28737.1 - 4.5e-45 152.5 0.4 1e-44 151.4 0.4 1.6 1 0 0 1 1 1 1 Transketolase, C-terminal domain Transket_pyr PF02779.24 EGC28737.1 - 2.6e-43 147.7 0.0 3.8e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain PFOR_II PF17147.4 EGC28737.1 - 0.00054 20.2 0.2 0.0017 18.7 0.0 1.9 2 0 0 2 2 2 1 Pyruvate:ferredoxin oxidoreductase core domain II Peptidase_M20 PF01546.28 EGC28737.1 - 0.11 12.2 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 Peptidase family M20/M25/M40 Myosin_TH1 PF06017.13 EGC28738.1 - 7.1e-06 25.8 1.8 0.00074 19.2 0.6 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding Pkinase PF00069.25 EGC28739.1 - 4.6e-67 226.2 0.3 3.7e-44 151.1 0.1 2.9 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28739.1 - 2.4e-28 99.1 0.0 2.3e-20 73.0 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC28739.1 - 0.00024 20.5 0.0 0.00093 18.6 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGC28739.1 - 0.0015 18.5 0.1 0.0041 17.1 0.1 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC28739.1 - 0.0018 17.4 0.1 0.0044 16.1 0.1 1.6 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGC28739.1 - 0.032 13.6 0.0 0.058 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Golgin_A5 PF09787.9 EGC28740.1 - 0.00064 19.3 34.8 0.00099 18.7 34.8 1.2 1 0 0 1 1 1 1 Golgin subfamily A member 5 Cas_DxTHG PF09455.10 EGC28740.1 - 0.002 17.8 10.5 0.0025 17.4 10.5 1.2 1 0 0 1 1 1 1 CRISPR-associated (Cas) DxTHG family Tektin PF03148.14 EGC28740.1 - 0.0068 15.2 27.6 1.2 7.9 27.6 2.1 1 1 0 1 1 1 1 Tektin family FAM184 PF15665.5 EGC28740.1 - 0.009 15.8 34.3 0.014 15.2 34.3 1.2 1 0 0 1 1 1 1 Family with sequence similarity 184, A and B CLZ PF16526.5 EGC28740.1 - 0.012 16.0 11.0 0.012 16.0 11.0 3.2 2 2 2 4 4 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nup88 PF10168.9 EGC28740.1 - 0.019 12.8 21.6 0.024 12.5 21.6 1.1 1 0 0 1 1 1 0 Nuclear pore component Exonuc_VII_L PF02601.15 EGC28740.1 - 0.026 14.1 17.2 0.036 13.7 17.2 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Atg14 PF10186.9 EGC28740.1 - 0.13 11.3 36.4 0.45 9.5 19.4 2.2 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 Leu_zip PF15294.6 EGC28740.1 - 0.13 11.8 37.6 0.23 10.9 30.0 2.0 1 1 1 2 2 2 0 Leucine zipper Uso1_p115_C PF04871.13 EGC28740.1 - 0.17 12.2 40.9 0.36 11.2 1.5 3.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF812 PF05667.11 EGC28740.1 - 0.19 10.6 31.9 0.26 10.1 31.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF812) FPP PF05911.11 EGC28740.1 - 0.19 9.8 30.3 0.24 9.5 30.3 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Jnk-SapK_ap_N PF09744.9 EGC28740.1 - 0.27 11.5 41.0 11 6.2 18.7 3.0 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 CEP63 PF17045.5 EGC28740.1 - 0.4 10.5 36.8 4.8 7.0 36.9 2.6 1 1 0 1 1 1 0 Centrosomal protein of 63 kDa Rootletin PF15035.6 EGC28740.1 - 0.45 10.5 37.5 0.22 11.5 15.7 2.4 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion TPR_MLP1_2 PF07926.12 EGC28740.1 - 0.57 10.3 41.7 0.7 10.0 8.7 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HAUS-augmin3 PF14932.6 EGC28740.1 - 0.65 9.5 33.9 1.8 8.1 7.3 2.1 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 CdvA PF18822.1 EGC28740.1 - 0.65 9.8 34.1 0.29 10.9 7.2 3.7 1 1 3 4 4 4 0 CdvA-like coiled-coil domain Nup54_57_C PF18570.1 EGC28740.1 - 0.9 9.2 12.6 0.11 12.1 1.0 3.2 3 0 0 3 3 2 0 NUP57/Nup54 C-terminal domain DUF1664 PF07889.12 EGC28740.1 - 0.98 9.5 21.7 4.1 7.5 6.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) CtIP_N PF10482.9 EGC28740.1 - 1.4 9.0 30.0 0.78 9.8 13.8 2.4 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain Retrotrans_gag PF03732.17 EGC28740.1 - 1.4 9.2 13.0 0.31 11.3 8.4 2.2 1 1 1 2 2 2 0 Retrotransposon gag protein ApoO PF09769.9 EGC28740.1 - 1.6 8.7 10.8 4.2 7.3 2.1 2.6 1 1 1 2 2 2 0 Apolipoprotein O DUF1640 PF07798.11 EGC28740.1 - 2 8.4 32.0 14 5.7 32.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) ADIP PF11559.8 EGC28740.1 - 2.1 8.4 39.7 11 6.1 29.2 2.4 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding DUF4407 PF14362.6 EGC28740.1 - 2.5 7.4 25.7 0.81 9.0 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF3972 PF13118.6 EGC28740.1 - 2.6 8.5 29.2 0.15 12.5 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF3972) DUF1451 PF07295.11 EGC28740.1 - 5 7.1 21.7 0.59 10.2 9.5 2.2 1 1 1 2 2 2 0 Zinc-ribbon containing domain APG6_N PF17675.1 EGC28740.1 - 6 7.4 45.2 2.9 8.4 31.2 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region Phage_GPO PF05929.11 EGC28740.1 - 6 6.4 27.4 3.4 7.2 14.4 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF883 PF05957.13 EGC28740.1 - 6.7 7.4 15.8 1.4 9.6 3.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF883) ACCA PF03255.14 EGC28740.1 - 7.3 6.5 26.3 0.87 9.5 6.5 2.9 1 1 2 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Spc7 PF08317.11 EGC28740.1 - 7.8 5.3 41.0 0.44 9.4 22.5 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3584 PF12128.8 EGC28740.1 - 8.9 3.7 37.2 18 2.7 37.2 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) EMG1 PF03587.14 EGC28741.1 - 2.8e-95 317.5 0.0 1.2e-94 315.5 0.0 1.8 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase DDHD PF02862.17 EGC28741.1 - 0.00035 20.8 0.4 0.00054 20.2 0.4 1.2 1 0 0 1 1 1 1 DDHD domain TRAP_alpha PF03896.16 EGC28741.1 - 0.0045 16.2 3.2 0.0063 15.8 3.2 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 EGC28741.1 - 0.0073 16.8 2.6 0.0093 16.4 2.6 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 Sporozoite_P67 PF05642.11 EGC28741.1 - 0.0097 14.1 7.9 0.013 13.6 7.9 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen CDC45 PF02724.14 EGC28741.1 - 0.017 13.4 4.9 0.021 13.1 4.9 1.1 1 0 0 1 1 1 0 CDC45-like protein TAF4 PF05236.14 EGC28741.1 - 0.03 14.1 6.2 0.05 13.4 6.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor TFIID component TAF4 family Nop14 PF04147.12 EGC28741.1 - 0.051 11.8 8.7 0.07 11.3 8.7 1.2 1 0 0 1 1 1 0 Nop14-like family DUF5308 PF17233.2 EGC28741.1 - 0.096 12.9 0.8 0.14 12.3 0.8 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) NPR3 PF03666.13 EGC28741.1 - 0.14 11.0 8.0 0.043 12.6 4.9 1.6 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 CPSF100_C PF13299.6 EGC28741.1 - 0.17 12.1 7.7 0.27 11.4 7.7 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Dicty_REP PF05086.12 EGC28741.1 - 0.17 9.8 10.1 0.26 9.2 10.1 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein RRN3 PF05327.11 EGC28741.1 - 0.4 9.2 4.7 0.57 8.7 4.7 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 MCM_bind PF09739.9 EGC28741.1 - 0.42 9.0 6.3 0.56 8.6 6.3 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Presenilin PF01080.17 EGC28741.1 - 0.52 9.0 5.3 0.68 8.6 5.3 1.1 1 0 0 1 1 1 0 Presenilin DUF913 PF06025.12 EGC28741.1 - 0.53 9.2 3.9 0.76 8.7 3.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Connexin PF00029.19 EGC28741.1 - 0.61 9.8 3.6 0.93 9.2 3.6 1.2 1 0 0 1 1 1 0 Connexin RabGAP-TBC PF00566.18 EGC28741.1 - 0.82 9.3 4.7 30 4.2 0.0 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain Paf1 PF03985.13 EGC28741.1 - 0.86 8.5 13.1 1.2 8.0 13.1 1.1 1 0 0 1 1 1 0 Paf1 Menin PF05053.13 EGC28741.1 - 1 7.6 4.8 1.3 7.3 4.8 1.1 1 0 0 1 1 1 0 Menin Tim54 PF11711.8 EGC28741.1 - 2.7 6.7 8.3 3.8 6.2 8.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Sec62 PF03839.16 EGC28741.1 - 2.7 7.4 7.3 4.1 6.8 7.3 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 Zip PF02535.22 EGC28741.1 - 3 7.0 4.1 4.1 6.5 4.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter GNAT_acetyltr_2 PF13718.6 EGC28741.1 - 5.5 6.3 6.3 4.7 6.5 4.7 1.6 2 0 0 2 2 2 0 GNAT acetyltransferase 2 DUF740 PF05340.12 EGC28742.1 - 0.0098 14.7 0.5 0.0098 14.7 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF740) DUF4168 PF13767.6 EGC28742.1 - 0.69 11.1 8.0 0.83 10.9 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) DUF4407 PF14362.6 EGC28742.1 - 0.72 9.1 3.8 0.72 9.2 3.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PPP4R2 PF09184.11 EGC28743.1 - 1.1e-25 90.8 12.0 1.6e-25 90.3 12.0 1.2 1 0 0 1 1 1 1 PPP4R2 P3A PF08727.11 EGC28745.1 - 0.046 13.1 0.1 0.047 13.1 0.1 1.2 1 0 0 1 1 1 0 Poliovirus 3A protein like AA_permease_N PF08403.10 EGC28747.1 - 0.12 11.9 0.2 0.23 11.0 0.2 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF4419 PF14388.6 EGC28748.1 - 5.6e-100 334.7 0.7 6.5e-100 334.4 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Acetyltransf_2 PF00797.17 EGC28749.1 - 5.6e-30 104.9 1.8 2.2e-29 102.9 1.8 1.7 1 1 0 1 1 1 1 N-acetyltransferase Ribonucleas_3_3 PF14622.6 EGC28750.1 - 0.00074 19.7 0.4 0.0044 17.2 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease-III-like DUF525 PF04379.14 EGC28751.1 - 4.2e-16 58.9 0.0 5.4e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 ApaG domain Activator-TraM PF11657.8 EGC28752.1 - 0.037 13.9 0.7 0.065 13.1 0.7 1.3 1 0 0 1 1 1 0 Transcriptional activator TraM Casc1_N PF15927.5 EGC28752.1 - 0.27 10.9 6.6 0.54 9.9 5.0 2.0 2 0 0 2 2 2 0 Cancer susceptibility candidate 1 N-terminus RE_HpaII PF09561.10 EGC28752.1 - 0.91 8.8 10.0 1.7 8.0 10.0 1.4 1 0 0 1 1 1 0 HpaII restriction endonuclease Peptidase_M16_C PF05193.21 EGC28753.1 - 1.3e-25 90.5 0.4 6.7e-25 88.2 0.0 2.3 3 1 0 3 3 3 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC28753.1 - 1.9e-23 83.1 0.0 4.3e-23 81.9 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) DUF5040 PF16443.5 EGC28753.1 - 0.11 11.9 0.2 0.19 11.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) Beta-lactamase PF00144.24 EGC28754.1 - 7.1e-42 143.8 0.0 1.1e-41 143.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M15 PF01427.17 EGC28754.1 - 1.3e-24 87.1 0.0 3.3e-24 85.8 0.0 1.7 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase Extensin-like_C PF06904.12 EGC28754.1 - 0.051 13.6 0.0 0.1 12.6 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus DUF3578 PF12102.8 EGC28755.1 - 0.065 12.8 0.5 5.7 6.5 0.1 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3578) p450 PF00067.22 EGC28757.1 - 1.1e-97 327.7 0.2 1.3e-97 327.5 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1002 PF06207.11 EGC28757.1 - 0.15 11.6 0.7 2.7 7.5 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1002) Band_7 PF01145.25 EGC28759.1 - 1.4e-22 80.6 1.0 3.2e-22 79.4 0.0 1.9 2 0 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGC28759.1 - 0.018 14.8 0.1 0.039 13.7 0.1 1.5 1 0 0 1 1 1 0 SPFH domain-Band 7 family DivIVA PF05103.13 EGC28759.1 - 7.7 6.6 8.7 61 3.7 8.4 2.1 1 1 0 1 1 1 0 DivIVA protein Flot PF15975.5 EGC28759.1 - 7.8 6.7 10.0 6.1 7.1 2.3 2.4 1 1 0 2 2 2 0 Flotillin LRR_6 PF13516.6 EGC28760.1 - 2.3e-28 95.8 48.3 0.00041 20.2 0.0 13.7 13 0 0 13 13 13 9 Leucine Rich repeat LRR_4 PF12799.7 EGC28760.1 - 9.2e-05 22.7 41.1 0.02 15.3 0.9 8.6 7 2 1 8 8 8 5 Leucine Rich repeats (2 copies) CDC45 PF02724.14 EGC28760.1 - 0.011 14.0 28.9 0.023 13.0 28.9 1.4 1 0 0 1 1 1 0 CDC45-like protein LRR_1 PF00560.33 EGC28760.1 - 0.1 13.2 29.4 18 6.4 0.1 11.2 11 2 0 11 11 11 0 Leucine Rich Repeat F-box-like PF12937.7 EGC28760.1 - 0.11 12.4 0.0 0.61 10.0 0.0 2.1 1 1 0 1 1 1 0 F-box-like Trypan_PARP PF05887.11 EGC28760.1 - 3 7.8 20.1 6.9 6.7 20.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Y_phosphatase PF00102.27 EGC28761.1 - 5.6e-73 245.4 3.1 3e-63 213.5 1.3 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.20 EGC28761.1 - 7.6e-09 35.5 0.0 2.2e-08 34.0 0.0 1.8 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGC28761.1 - 0.00033 20.8 0.1 0.0015 18.7 0.0 2.1 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGC28761.1 - 0.00033 20.7 0.0 0.00085 19.4 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family ICAP-1_inte_bdg PF10480.9 EGC28761.1 - 0.062 13.3 0.1 0.13 12.3 0.1 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein HSBP1 PF06825.12 EGC28762.1 - 4.6e-22 77.6 3.4 7.9e-22 76.9 3.4 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 DUF3086 PF11285.8 EGC28762.1 - 0.0038 16.4 3.0 0.0039 16.3 3.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3086) ABC_tran_CTD PF16326.5 EGC28762.1 - 0.066 13.5 2.2 0.12 12.6 2.2 1.5 1 0 0 1 1 1 0 ABC transporter C-terminal domain YvrJ PF12841.7 EGC28762.1 - 0.081 12.5 0.2 0.37 10.3 0.1 2.0 1 1 1 2 2 2 0 YvrJ protein family DUF1664 PF07889.12 EGC28762.1 - 0.14 12.2 5.0 0.25 11.4 5.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Menin PF05053.13 EGC28762.1 - 0.16 10.3 9.0 0.14 10.5 9.0 1.1 1 0 0 1 1 1 0 Menin ALMT PF11744.8 EGC28762.1 - 0.19 10.5 12.5 0.21 10.4 12.5 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4758 PF15950.5 EGC28762.1 - 0.21 11.9 6.4 0.29 11.5 6.4 1.2 1 0 0 1 1 1 0 Putative sperm flagellar membrane protein DUF4611 PF15387.6 EGC28762.1 - 0.73 10.1 8.1 0.83 9.9 7.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4611) RP-C_C PF11800.8 EGC28762.1 - 1.4 8.9 8.3 1.8 8.6 8.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Prominin PF05478.11 EGC28762.1 - 3 5.7 12.6 3.3 5.5 12.6 1.0 1 0 0 1 1 1 0 Prominin DUF4407 PF14362.6 EGC28762.1 - 3.3 7.0 7.2 3.4 6.9 7.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) p450 PF00067.22 EGC28763.1 - 7.2e-58 196.5 0.0 9e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 adh_short PF00106.25 EGC28764.1 - 4.2e-46 156.9 0.0 3.4e-45 153.9 0.0 1.9 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28764.1 - 6e-26 91.4 0.0 7.9e-26 91.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28764.1 - 1.8e-15 57.3 0.0 2.6e-15 56.8 0.0 1.2 1 0 0 1 1 1 1 KR domain THF_DHG_CYH_C PF02882.19 EGC28764.1 - 1e-05 24.9 0.0 1.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Polysacc_synt_2 PF02719.15 EGC28764.1 - 0.0038 16.4 0.2 0.0061 15.7 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Shikimate_DH PF01488.20 EGC28764.1 - 0.012 15.7 0.1 0.021 14.9 0.1 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGC28764.1 - 0.016 15.7 0.1 0.032 14.7 0.1 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding 3Beta_HSD PF01073.19 EGC28764.1 - 0.02 13.9 0.1 0.03 13.3 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC28764.1 - 0.02 14.3 0.0 0.038 13.4 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family IPPT PF01715.17 EGC28765.1 - 1.6e-50 172.1 1.1 2e-50 171.8 1.1 1.1 1 0 0 1 1 1 1 IPP transferase IPT PF01745.16 EGC28765.1 - 1.9e-07 30.8 0.0 4.6e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase Zeta_toxin PF06414.12 EGC28765.1 - 3.3e-05 23.3 0.1 0.00013 21.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin RNA_helicase PF00910.22 EGC28765.1 - 0.00067 20.0 3.2 0.046 14.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_16 PF13191.6 EGC28765.1 - 0.0053 17.2 0.0 0.011 16.1 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGC28765.1 - 0.0071 16.5 0.0 0.016 15.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGC28765.1 - 0.01 16.1 0.2 0.048 13.9 0.0 2.3 3 1 1 4 4 4 0 AAA domain baeRF_family7 PF18849.1 EGC28765.1 - 0.022 15.0 1.5 0.71 10.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 7 Imm2 PF14426.6 EGC28765.1 - 0.03 14.4 0.2 0.23 11.6 0.0 2.2 1 1 1 2 2 2 0 Immunity protein Imm2 Hpr_kinase_C PF07475.12 EGC28765.1 - 0.049 13.2 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain ParA PF10609.9 EGC28765.1 - 0.065 12.7 0.1 0.12 11.8 0.1 1.4 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase AAA PF00004.29 EGC28765.1 - 0.088 13.2 0.0 0.29 11.6 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGC28765.1 - 0.14 12.7 1.8 0.77 10.3 0.2 2.4 2 1 0 2 2 2 0 AAA domain ResIII PF04851.15 EGC28765.1 - 0.18 11.8 0.1 0.18 11.8 0.1 2.5 2 2 0 2 2 2 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EGC28765.1 - 2.5 8.6 5.7 0.58 10.7 0.9 2.2 2 1 0 2 2 2 0 ABC transporter Endotoxin_N PF03945.14 EGC28766.1 - 4.5e-05 23.3 0.0 0.018 14.7 0.0 2.2 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain Coiled PF05710.12 EGC28767.1 - 3 8.7 13.0 3.9 8.4 13.0 1.4 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.12 EGC28768.1 - 0.46 11.3 8.5 0.57 11.0 8.5 1.3 1 1 0 1 1 1 0 Coiled coil adh_short PF00106.25 EGC28769.1 - 2.1e-21 76.3 0.2 2.3e-15 56.6 0.0 2.6 2 1 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28769.1 - 3.5e-14 52.9 0.0 7.1e-09 35.6 0.0 2.5 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28769.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGC28769.1 - 0.021 14.2 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase NOB1_Zn_bind PF08772.11 EGC28769.1 - 0.026 14.7 0.1 0.076 13.2 0.1 1.7 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Epimerase PF01370.21 EGC28769.1 - 0.028 13.9 0.0 0.057 12.9 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family FNIP PF05725.12 EGC28770.1 - 1.5e-24 85.9 43.2 4e-12 46.1 4.5 10.9 6 3 8 14 14 14 11 FNIP Repeat DUF1769 PF08588.10 EGC28770.1 - 0.033 14.4 0.9 3.6 7.8 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1769) Coiled PF05710.12 EGC28771.1 - 0.017 15.9 4.6 0.019 15.8 4.6 1.1 1 0 0 1 1 1 0 Coiled coil G-alpha PF00503.20 EGC28772.1 - 1.4e-112 376.4 5.2 2.2e-112 375.8 5.2 1.3 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC28772.1 - 3.5e-15 55.9 0.3 3.2e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC28772.1 - 2.3e-06 27.2 0.9 0.00066 19.1 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGC28772.1 - 1.9e-05 24.9 0.4 0.032 14.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC28772.1 - 0.04 14.0 0.1 3.1 7.9 0.0 2.6 2 1 1 3 3 3 0 50S ribosome-binding GTPase LolA PF03548.15 EGC28772.1 - 0.063 13.0 0.5 0.24 11.1 0.1 2.2 3 1 0 3 3 3 0 Outer membrane lipoprotein carrier protein LolA AAA_29 PF13555.6 EGC28772.1 - 0.072 12.8 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EGC28772.1 - 0.17 11.4 0.0 0.6 9.6 0.0 2.0 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PCMT PF01135.19 EGC28773.1 - 5.6e-60 202.7 0.0 6.9e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_31 PF13847.6 EGC28773.1 - 2.4e-09 37.1 0.0 3.7e-09 36.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC28773.1 - 1.6e-07 31.9 0.0 4.1e-07 30.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC28773.1 - 5.3e-06 27.0 0.0 1.1e-05 26.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC28773.1 - 1.3e-05 25.8 0.0 2.8e-05 24.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC28773.1 - 1.5e-05 24.9 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC28773.1 - 0.00013 21.8 0.0 0.00022 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGC28773.1 - 0.00071 19.6 0.0 0.00093 19.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC28773.1 - 0.0031 17.1 0.0 0.0053 16.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGC28773.1 - 0.0071 15.7 0.0 0.011 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 EGC28773.1 - 0.021 14.5 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 16S rRNA methyltransferase RsmB/F GidB PF02527.15 EGC28773.1 - 0.027 13.8 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_24 PF13578.6 EGC28773.1 - 0.072 14.1 0.0 0.14 13.2 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_3 PF01596.17 EGC28773.1 - 0.13 11.4 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 O-methyltransferase Fibrillarin PF01269.17 EGC28773.1 - 0.17 11.0 0.2 0.5 9.4 0.0 1.8 2 0 0 2 2 2 0 Fibrillarin CrgA PF06781.12 EGC28774.1 - 0.62 10.2 0.0 0.62 10.2 0.0 3.7 3 2 2 5 5 5 0 Cell division protein CrgA Herpes_U5 PF05999.11 EGC28775.1 - 0.00026 19.9 0.1 0.00035 19.4 0.1 1.1 1 0 0 1 1 1 1 Herpesvirus U5-like family F-box-like PF12937.7 EGC28775.1 - 0.00062 19.6 0.8 0.0013 18.6 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box_5 PF18511.1 EGC28775.1 - 0.074 12.6 0.4 0.2 11.3 0.4 1.7 1 0 0 1 1 1 0 F-box POX PF07526.11 EGC28775.1 - 0.18 12.4 2.6 4.1 8.0 0.2 2.2 2 0 0 2 2 2 0 Associated with HOX Secretin_N_2 PF07655.13 EGC28775.1 - 7.5 7.2 25.3 0.22 12.1 8.0 2.6 2 0 0 2 2 2 0 Secretin N-terminal domain Orf78 PF06024.12 EGC28775.1 - 8.4 6.8 15.7 2 8.7 4.2 2.5 2 0 0 2 2 2 0 Orf78 (ac78) UQ_con PF00179.26 EGC28776.1 - 6.9e-20 71.1 0.0 8.5e-20 70.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC28776.1 - 0.16 12.2 0.0 0.18 12.1 0.0 1.4 1 1 0 1 1 1 0 RWD domain Pkinase_Tyr PF07714.17 EGC28777.1 - 3.9e-60 203.3 0.0 6.2e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC28777.1 - 5.2e-51 173.5 0.0 9.5e-51 172.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGC28777.1 - 3.8e-11 42.9 0.0 9.7e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 SH2 domain SH2_2 PF14633.6 EGC28777.1 - 0.012 15.0 0.1 0.68 9.3 0.0 2.3 2 0 0 2 2 2 0 SH2 domain APH PF01636.23 EGC28777.1 - 0.044 13.7 0.0 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Macoilin PF09726.9 EGC28777.1 - 2.9 6.3 19.6 4.1 5.8 19.6 1.2 1 0 0 1 1 1 0 Macoilin family DnaJ_C PF01556.18 EGC28778.1 - 2.2e-05 24.6 0.2 2.6e-05 24.3 0.2 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain Atg14 PF10186.9 EGC28780.1 - 2.1e-12 46.8 17.3 2.1e-12 46.8 17.3 4.2 3 1 0 3 3 3 1 Vacuolar sorting 38 and autophagy-related subunit 14 APG6 PF04111.12 EGC28780.1 - 3.7e-08 33.5 0.0 3.7e-08 33.5 0.0 2.7 3 0 0 3 3 3 1 Apg6 BARA domain BORCS8 PF10167.9 EGC28781.1 - 1.4e-31 108.8 3.6 1.4e-31 108.8 3.6 1.9 2 0 0 2 2 2 1 BLOC-1-related complex sub-unit 8 MVP_shoulder PF11978.8 EGC28782.1 - 0.026 14.6 2.2 0.064 13.3 2.2 1.7 1 0 0 1 1 1 0 Shoulder domain DUF3677 PF12432.8 EGC28783.1 - 0.05 13.9 0.3 6.2 7.2 0.2 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) ILEI PF15711.5 EGC28784.1 - 1.6e-13 50.9 0.1 3.1e-13 50.0 0.1 1.5 1 0 0 1 1 1 1 Interleukin-like EMT inducer Pkinase PF00069.25 EGC28785.1 - 1.2e-76 257.6 0.1 2e-76 256.8 0.1 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28785.1 - 3.8e-40 137.8 0.0 5.9e-40 137.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC28785.1 - 2.3e-08 33.7 0.0 3.8e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGC28785.1 - 8e-05 21.6 2.8 0.0004 19.3 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGC28785.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family PRP1_N PF06424.12 EGC28785.1 - 0.056 13.8 6.9 0.089 13.2 6.9 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DAHP_synth_1 PF00793.20 EGC28785.1 - 0.084 11.7 0.2 0.96 8.3 0.0 2.1 2 0 0 2 2 2 0 DAHP synthetase I family Roughex PF06020.11 EGC28785.1 - 2.1 7.4 10.9 3 6.8 10.9 1.1 1 0 0 1 1 1 0 Drosophila roughex protein SLM4 PF16818.5 EGC28785.1 - 3 7.8 9.5 2.6 8.0 5.4 2.4 2 0 0 2 2 2 0 Protein SLM4 AAA_12 PF13087.6 EGC28786.1 - 4.3e-39 134.2 0.3 4.3e-39 134.2 0.3 2.7 2 1 0 3 3 2 1 AAA domain AAA_11 PF13086.6 EGC28786.1 - 1e-24 87.8 0.7 1e-24 87.8 0.7 5.2 4 1 0 4 4 4 1 AAA domain AAA_19 PF13245.6 EGC28786.1 - 8.4e-09 35.9 0.0 6.4e-08 33.1 0.0 2.2 1 1 0 1 1 1 1 AAA domain SAM_1 PF00536.30 EGC28786.1 - 1.7e-08 34.8 0.1 5.4e-08 33.2 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_30 PF13604.6 EGC28786.1 - 9.2e-07 28.8 0.0 0.00034 20.4 0.0 2.2 2 0 0 2 2 2 2 AAA domain SAM_2 PF07647.17 EGC28786.1 - 1.7e-06 28.1 0.1 6.4e-06 26.2 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 EGC28786.1 - 0.0027 17.5 0.1 0.0077 16.0 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC28786.1 - 0.017 15.1 0.0 0.047 13.7 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA_5 PF07728.14 EGC28786.1 - 0.023 14.7 0.0 0.073 13.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGC28786.1 - 0.029 14.6 0.0 0.073 13.2 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC28786.1 - 0.082 13.2 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGC28786.1 - 0.085 13.2 0.0 0.21 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PIP5K PF01504.18 EGC28788.1 - 1.4e-68 231.2 9.8 1.4e-68 231.2 9.8 3.4 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Fz PF01392.22 EGC28790.1 - 6.8e-06 26.7 4.5 1.5e-05 25.6 4.5 1.5 1 0 0 1 1 1 1 Fz domain Frizzled PF01534.17 EGC28790.1 - 2.6e-05 23.4 13.7 5e-05 22.5 13.7 1.4 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGC28790.1 - 0.0091 15.3 11.3 0.014 14.7 11.3 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TPR_1 PF00515.28 EGC28791.1 - 1.4e-16 59.5 2.5 1.2e-05 24.9 0.3 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC28791.1 - 1.7e-12 46.5 3.5 8e-05 22.6 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC28791.1 - 1.1e-10 41.0 3.7 6.1e-09 35.4 0.3 2.7 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.17 EGC28791.1 - 1.3e-09 37.4 2.5 0.0077 16.3 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC28791.1 - 9.1e-08 32.3 0.1 0.00067 20.3 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC28791.1 - 3.6e-07 30.7 0.2 1e-05 26.1 0.0 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC28791.1 - 2.7e-05 24.2 0.3 0.0016 18.7 0.1 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC28791.1 - 0.00043 20.7 0.1 0.019 15.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC28791.1 - 0.0011 19.2 0.9 0.016 15.5 0.2 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC28791.1 - 0.0028 18.2 0.5 4.7 8.1 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.10 EGC28791.1 - 0.0028 16.7 0.0 0.0031 16.6 0.0 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC3 PF12895.7 EGC28791.1 - 0.063 13.5 2.7 0.12 12.6 2.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 UCH PF00443.29 EGC28792.1 - 1.1e-07 31.7 9.2 1.1e-07 31.7 9.2 5.3 3 1 1 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase OrfB_Zn_ribbon PF07282.11 EGC28792.1 - 0.0018 18.1 3.4 0.05 13.5 0.0 3.5 3 0 0 3 3 3 1 Putative transposase DNA-binding domain RecR PF02132.15 EGC28792.1 - 0.18 11.4 3.5 13 5.5 0.0 3.4 3 0 0 3 3 3 0 RecR protein Cytochrom_C1 PF02167.15 EGC28793.1 - 4.4e-91 304.5 0.0 5.2e-91 304.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.6 EGC28793.1 - 0.00023 21.4 0.0 0.00044 20.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.21 EGC28793.1 - 0.078 14.1 0.3 0.17 13.0 0.3 1.7 1 1 0 1 1 1 0 Cytochrome c Ribosomal_60s PF00428.19 EGC28794.1 - 3.2e-26 91.7 8.0 3.8e-26 91.5 8.0 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Phage_holin_6_1 PF09682.10 EGC28794.1 - 0.0062 16.9 1.6 1.3 9.5 0.1 2.1 2 0 0 2 2 2 2 Bacteriophage holin of superfamily 6 (Holin_LLH) DUF2057 PF09829.9 EGC28794.1 - 0.13 12.5 2.2 0.18 12.0 2.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) PepSY_2 PF13670.6 EGC28794.1 - 0.34 11.0 5.6 3.6 7.6 5.2 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain WD40 PF00400.32 EGC28795.1 - 8.3e-44 146.7 11.4 2.1e-09 37.8 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC28795.1 - 7.4e-11 42.2 0.2 0.022 15.1 0.1 5.0 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC28795.1 - 5.3e-07 28.7 1.3 0.34 9.5 0.3 4.8 2 1 3 5 5 5 3 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGC28795.1 - 1e-05 24.7 0.2 0.25 10.3 0.0 4.5 3 1 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nucleoporin_N PF08801.11 EGC28795.1 - 0.00028 19.8 0.0 4.6 5.9 0.0 3.9 2 1 3 5 5 5 2 Nup133 N terminal like PALB2_WD40 PF16756.5 EGC28795.1 - 0.026 13.5 1.6 0.22 10.4 0.1 2.7 2 1 1 3 3 3 0 Partner and localizer of BRCA2 WD40 domain Peptidase_S8 PF00082.22 EGC28795.1 - 0.026 13.8 0.0 0.04 13.2 0.0 1.2 1 0 0 1 1 1 0 Subtilase family Cytochrom_D1 PF02239.16 EGC28795.1 - 0.037 12.5 0.0 8.5 4.8 0.0 2.7 2 1 0 3 3 3 0 Cytochrome D1 heme domain MaoC_dehydratas PF01575.19 EGC28796.1 - 8.4e-32 109.3 0.0 3.1e-31 107.5 0.0 1.8 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGC28796.1 - 1.2e-06 28.7 0.0 0.00032 20.8 0.0 2.4 2 0 0 2 2 2 2 N-terminal half of MaoC dehydratase zf-A20 PF01754.16 EGC28798.1 - 8.9e-12 44.7 5.2 8.9e-12 44.7 5.2 2.2 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 EGC28798.1 - 2.2e-09 37.3 10.1 2.2e-09 37.3 10.1 2.0 3 0 0 3 3 3 1 AN1-like Zinc finger DUF4428 PF14471.6 EGC28798.1 - 7.5 6.6 10.6 0.58 10.1 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) DCX PF03607.17 EGC28799.1 - 3.6e-33 113.4 0.2 3.4e-17 62.3 0.0 2.3 2 0 0 2 2 2 2 Doublecortin UB2H PF14814.6 EGC28799.1 - 0.012 15.6 0.1 6.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain PFL-like PF02901.15 EGC28799.1 - 0.042 12.5 0.3 4.2 5.9 0.0 2.0 2 0 0 2 2 2 0 Pyruvate formate lyase-like RhoGEF PF00621.20 EGC28800.1 - 1.1e-39 136.6 9.1 3.3e-39 135.0 9.1 1.9 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.31 EGC28800.1 - 9.2e-09 35.5 0.4 4.2e-08 33.3 0.4 2.2 1 0 0 1 1 1 1 Calponin homology (CH) domain IQ PF00612.27 EGC28800.1 - 0.00075 19.1 0.7 0.0018 17.9 0.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 EGC28800.1 - 0.0037 17.8 0.1 4.8 7.7 0.0 2.8 2 0 0 2 2 2 2 PH domain IQ_SEC7_PH PF16453.5 EGC28800.1 - 0.027 14.4 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 PH domain Pox_A28 PF04584.14 EGC28801.1 - 0.066 13.4 3.9 0.094 12.9 3.9 1.3 1 1 0 1 1 1 0 Poxvirus A28 family TRAPP PF04051.16 EGC28802.1 - 7.6e-37 126.3 0.2 9.2e-37 126.0 0.2 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Synaptonemal_3 PF15191.6 EGC28802.1 - 0.013 15.2 0.7 2 8.3 0.0 2.9 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Usp PF00582.26 EGC28803.1 - 4.5e-13 49.9 0.0 5.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family 2-Hacid_dh PF00389.30 EGC28803.1 - 0.11 12.1 0.0 0.22 11.2 0.0 1.5 1 1 1 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cpn60_TCP1 PF00118.24 EGC28804.1 - 2.2e-164 547.7 4.1 2.7e-164 547.4 4.1 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FNIP PF05725.12 EGC28805.1 - 8e-19 67.5 31.6 7.3e-08 32.4 0.2 7.9 4 2 2 7 7 7 6 FNIP Repeat RhoGAP PF00620.27 EGC28806.1 - 6.5e-45 152.7 0.0 1.6e-44 151.4 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain IPK PF03770.16 EGC28806.1 - 1.1e-44 152.7 0.0 1.9e-44 151.9 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CRAL_TRIO_2 PF13716.6 EGC28806.1 - 9.6e-39 132.7 3.8 2e-38 131.7 3.2 1.8 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGC28806.1 - 1.8e-11 44.0 1.2 3.4e-11 43.1 1.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2810 PF10928.8 EGC28806.1 - 0.086 12.9 0.0 0.21 11.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Pkinase_Tyr PF07714.17 EGC28807.1 - 6.6e-53 179.6 0.0 1.5e-52 178.4 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC28807.1 - 8.9e-49 166.2 0.0 1e-47 162.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC28807.1 - 0.00042 19.2 0.0 0.00066 18.6 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC28807.1 - 0.0024 16.9 0.1 0.0044 16.0 0.1 1.4 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGC28807.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC28807.1 - 0.037 13.4 0.0 0.056 12.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC28807.1 - 0.05 12.9 0.0 0.093 12.0 0.0 1.4 1 1 0 1 1 1 0 Kinase-like AIRS_C PF02769.22 EGC28809.1 - 0.11 12.6 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain EGF_2 PF07974.13 EGC28810.1 - 4.4e-05 23.8 33.7 0.018 15.4 13.2 2.9 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC28810.1 - 6.2e-05 23.1 19.8 0.039 14.1 6.4 2.6 2 0 0 2 2 2 2 Laminin EGF domain TMEM154 PF15102.6 EGC28810.1 - 0.47 10.4 4.4 0.14 12.1 0.4 2.1 2 0 0 2 2 2 0 TMEM154 protein family Gamma-thionin PF00304.20 EGC28810.1 - 0.65 10.3 17.9 0.079 13.2 3.0 2.5 2 0 0 2 2 2 0 Gamma-thionin family EGF_2 PF07974.13 EGC28811.1 - 0.0087 16.4 12.9 0.0087 16.4 12.9 2.1 3 0 0 3 3 3 1 EGF-like domain CBM77 PF18283.1 EGC28811.1 - 0.022 15.1 0.1 0.038 14.4 0.1 1.4 1 0 0 1 1 1 0 Carbohydrate binding module 77 Presenilin PF01080.17 EGC28813.1 - 0.00016 20.6 15.2 0.00016 20.6 15.2 2.4 2 0 0 2 2 2 1 Presenilin CCSAP PF15748.5 EGC28813.1 - 1.4 9.0 57.9 0.15 12.2 28.5 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated MDM1 PF15501.6 EGC28813.1 - 2.3 7.2 61.8 0.019 14.1 31.9 2.3 2 0 0 2 2 2 0 Nuclear protein MDM1 Histone_H2A_C PF16211.5 EGC28814.1 - 3.5e-09 36.3 0.1 7.1e-09 35.2 0.1 1.5 2 0 0 2 2 2 1 C-terminus of histone H2A Histone PF00125.24 EGC28814.1 - 4e-07 30.4 0.1 5.3e-07 30.1 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC28814.1 - 0.00022 21.4 0.0 0.00034 20.9 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phospholamban PF04272.14 EGC28815.1 - 0.065 12.7 2.2 0.094 12.2 2.2 1.3 1 0 0 1 1 1 0 Phospholamban ABC_membrane PF00664.23 EGC28816.1 - 1.3e-55 189.0 45.5 2.8e-31 109.2 20.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC28816.1 - 1.1e-48 165.2 0.1 2.5e-28 99.3 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGC28816.1 - 3.8e-11 42.9 3.1 0.00037 20.0 0.5 4.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGC28816.1 - 7.7e-07 29.1 0.0 0.0074 16.0 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_23 PF13476.6 EGC28816.1 - 4.4e-06 27.3 5.9 0.0039 17.7 0.1 3.4 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.6 EGC28816.1 - 5.4e-05 23.2 0.6 2.1 8.1 0.1 4.2 3 1 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGC28816.1 - 5.5e-05 23.2 1.4 0.43 10.7 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGC28816.1 - 7.6e-05 22.4 0.6 0.44 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC28816.1 - 0.0011 19.2 0.2 0.65 10.3 0.0 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGC28816.1 - 0.0013 18.6 0.1 0.36 10.7 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGC28816.1 - 0.0046 16.3 0.0 1.9 7.8 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_7 PF12775.7 EGC28816.1 - 0.0057 16.2 0.1 2 7.9 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region TsaE PF02367.17 EGC28816.1 - 0.0058 16.6 0.0 4.5 7.3 0.0 2.6 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EGC28816.1 - 0.017 15.3 3.7 0.87 9.6 0.3 3.0 3 0 0 3 3 2 0 Helicase HerA, central domain RNA_helicase PF00910.22 EGC28816.1 - 0.02 15.3 0.5 11 6.4 0.1 3.3 4 0 0 4 4 2 0 RNA helicase Zeta_toxin PF06414.12 EGC28816.1 - 0.021 14.1 0.3 6.8 5.9 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.6 EGC28816.1 - 0.03 14.0 0.2 6.6 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGC28816.1 - 0.033 13.8 0.0 0.84 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGC28816.1 - 0.066 13.6 0.0 7.7 6.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGC28816.1 - 0.081 13.5 2.4 2.9 8.4 0.1 3.0 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 EGC28816.1 - 0.091 12.5 0.0 20 4.9 0.0 2.8 3 0 0 3 3 2 0 IstB-like ATP binding protein PduV-EutP PF10662.9 EGC28816.1 - 0.11 12.2 0.7 4.7 7.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Sigma54_activat PF00158.26 EGC28816.1 - 0.11 12.2 0.0 6 6.5 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain MNSV_P7B PF06692.11 EGC28816.1 - 0.12 12.4 0.9 0.47 10.5 0.1 2.6 2 0 0 2 2 1 0 Melon necrotic spot virus P7B protein MeaB PF03308.16 EGC28816.1 - 0.13 11.2 0.1 0.62 9.0 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB T2SSE PF00437.20 EGC28816.1 - 0.13 11.3 0.1 13 4.7 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein Roc PF08477.13 EGC28816.1 - 0.13 12.5 0.6 22 5.3 0.0 2.9 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EGC28816.1 - 0.15 12.2 0.3 20 5.3 0.0 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGC28816.1 - 0.15 11.9 2.5 28 4.6 0.2 3.2 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.25 EGC28816.1 - 0.18 11.4 0.2 3.9 7.1 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ResIII PF04851.15 EGC28816.1 - 0.26 11.3 1.6 8.4 6.4 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NB-ARC PF00931.22 EGC28816.1 - 0.29 10.3 1.6 1.5 7.9 0.1 2.2 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EGC28816.1 - 0.38 10.3 2.7 0.54 9.8 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AzlC PF03591.14 EGC28816.1 - 1.8 9.0 7.5 0.68 10.4 2.3 2.8 1 1 1 2 2 2 0 AzlC protein TrwB_AAD_bind PF10412.9 EGC28816.1 - 3 6.7 4.9 8.2 5.2 0.1 2.5 3 0 0 3 3 3 0 Type IV secretion-system coupling protein DNA-binding domain SPX PF03105.19 EGC28817.1 - 2 8.3 6.9 2.7 7.8 6.9 1.1 1 0 0 1 1 1 0 SPX domain ERM PF00769.19 EGC28818.1 - 5.5e-05 23.1 25.4 5.5e-05 23.1 25.4 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TALPID3 PF15324.6 EGC28819.1 - 0.064 10.9 6.2 0.078 10.6 6.2 1.0 1 0 0 1 1 1 0 Hedgehog signalling target DUF1797 PF08796.10 EGC28819.1 - 3.6 7.8 6.1 1.9 8.7 1.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1797) TACC_C PF05010.14 EGC28820.1 - 1.6e-05 24.8 24.2 0.00042 20.1 10.8 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal VP4_haemagglut PF00426.18 EGC28820.1 - 0.024 14.8 0.7 0.056 13.6 0.1 1.7 1 1 1 2 2 2 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain DUF2099 PF09872.9 EGC28820.1 - 0.043 13.0 0.6 0.079 12.1 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2099) FNIP PF05725.12 EGC28821.1 - 2.7e-103 337.9 42.7 3.9e-15 55.7 3.4 9.3 7 2 2 9 9 9 9 FNIP Repeat Peptidase_S78 PF04586.17 EGC28821.1 - 0.018 15.2 0.0 41 4.3 0.0 4.1 3 2 0 4 4 4 0 Caudovirus prohead serine protease LRR_1 PF00560.33 EGC28821.1 - 2.8 8.8 9.9 72 4.5 0.0 7.1 4 2 2 6 6 6 0 Leucine Rich Repeat Mito_carr PF00153.27 EGC28822.1 - 6.1e-68 224.8 3.3 7.8e-22 77.0 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PTEN_C2 PF10409.9 EGC28823.1 - 9.5e-20 70.7 4.8 9.4e-18 64.3 4.8 2.7 1 1 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGC28823.1 - 3.2e-05 23.8 0.1 3.2e-05 23.8 0.1 2.7 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGC28823.1 - 0.00015 21.8 0.0 0.00031 20.8 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGC28823.1 - 0.0021 17.7 0.0 0.0061 16.1 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC28823.1 - 0.2 11.8 0.2 0.2 11.8 0.2 3.1 3 1 0 3 3 3 0 Inositol hexakisphosphate TFIIA PF03153.13 EGC28824.1 - 0.21 11.5 24.8 0.24 11.4 24.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FYTT PF07078.11 EGC28824.1 - 0.74 9.1 12.7 1 8.6 12.7 1.1 1 0 0 1 1 1 0 Forty-two-three protein FAM222A PF15258.6 EGC28824.1 - 2.2 7.3 17.7 3 6.9 17.7 1.3 1 0 0 1 1 1 0 Protein family of FAM222A LMBR1 PF04791.16 EGC28824.1 - 5.9 5.7 11.4 6.3 5.6 11.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Auxin_canalis PF05703.11 EGC28824.1 - 9.8 6.0 6.1 14 5.5 6.1 1.2 1 0 0 1 1 1 0 Auxin canalisation HSF_DNA-bind PF00447.17 EGC28825.1 - 0.086 13.5 3.4 0.36 11.5 3.4 1.9 1 1 0 1 1 1 0 HSF-type DNA-binding Cyt_bd_oxida_II PF02322.15 EGC28827.1 - 0.0035 16.7 0.6 0.0049 16.3 0.6 1.1 1 0 0 1 1 1 1 Cytochrome bd terminal oxidase subunit II LtrA PF06772.11 EGC28827.1 - 0.011 15.0 7.0 0.017 14.4 7.0 1.3 1 0 0 1 1 1 0 Bacterial low temperature requirement A protein (LtrA) NrsF PF06532.11 EGC28827.1 - 0.015 15.0 0.1 0.019 14.7 0.1 1.3 1 0 0 1 1 1 0 Negative regulator of sigma F DUF2070 PF09843.9 EGC28827.1 - 0.042 12.2 4.7 0.054 11.8 4.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PRY PF13765.6 EGC28827.1 - 0.087 12.5 0.0 2.7 7.7 0.0 2.3 2 0 0 2 2 2 0 SPRY-associated domain 7TMR-DISM_7TM PF07695.11 EGC28827.1 - 0.091 12.6 9.5 0.19 11.6 9.4 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling Toxin_10 PF05431.11 EGC28828.1 - 0.093 12.2 0.3 0.12 11.9 0.3 1.2 1 0 0 1 1 1 0 Insecticidal Crystal Toxin, P42 PMC2NT PF08066.12 EGC28829.1 - 0.07 13.8 2.6 0.77 10.5 0.1 2.1 1 1 1 2 2 2 0 PMC2NT (NUC016) domain Myb_DNA-binding PF00249.31 EGC28830.1 - 3e-11 43.3 0.2 5.4e-11 42.5 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC28830.1 - 0.011 15.7 0.6 0.011 15.7 0.6 2.2 3 0 0 3 3 3 0 Myb DNA-binding like Myb_DNA-bind_6 PF13921.6 EGC28830.1 - 0.02 15.1 0.4 0.071 13.4 0.4 2.0 2 0 0 2 2 2 0 Myb-like DNA-binding domain Prok-TraM PF09228.10 EGC28831.1 - 5.9 7.3 10.5 13 6.2 0.5 3.9 3 0 0 3 3 3 0 Prokaryotic Transcriptional repressor TraM ApoO PF09769.9 EGC28831.1 - 6.8 6.7 18.3 6.6 6.7 0.5 4.7 4 0 0 4 4 4 0 Apolipoprotein O DUF4611 PF15387.6 EGC28832.1 - 2.6 8.3 14.6 0.52 10.6 8.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) FNIP_M PF14637.6 EGC28833.1 - 2.6e-49 168.2 1.2 4.2e-49 167.6 1.2 1.3 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_C PF14638.6 EGC28833.1 - 1.8e-17 63.6 0.0 8.1e-17 61.5 0.0 2.1 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus FNIP_N PF14636.6 EGC28833.1 - 1.1e-09 39.4 14.3 4.3e-08 34.3 0.0 4.4 3 1 1 4 4 4 2 Folliculin-interacting protein N-terminus Longin_2 PF18639.1 EGC28833.1 - 0.028 14.3 0.0 0.13 12.2 0.0 2.1 1 0 0 1 1 1 0 Yeast longin domain BSD PF03909.17 EGC28834.1 - 8.9e-13 48.0 1.9 8.9e-13 48.0 1.9 3.1 4 0 0 4 4 4 1 BSD domain VGCC_beta4Aa_N PF12052.8 EGC28834.1 - 5.6 7.2 7.7 17 5.6 7.7 1.8 1 0 0 1 1 1 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal Peptidase_C26 PF07722.13 EGC28835.1 - 5.1e-16 59.1 0.0 7.1e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGC28835.1 - 4.6e-08 33.1 0.0 7.5e-08 32.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGC28836.1 - 2.5e-19 69.9 0.0 6.5e-19 68.5 0.0 1.6 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGC28836.1 - 3.2e-09 36.8 0.0 4.9e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I DHHC PF01529.20 EGC28837.1 - 5.4e-21 75.1 25.5 5.4e-21 75.1 25.5 2.9 1 1 2 3 3 3 2 DHHC palmitoyltransferase TMEM43 PF07787.12 EGC28837.1 - 0.089 12.2 6.5 2.7 7.3 2.7 2.6 2 0 0 2 2 2 0 Transmembrane protein 43 DUF1272 PF06906.11 EGC28837.1 - 0.18 11.9 5.2 0.42 10.7 5.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) EB PF01683.18 EGC28838.1 - 0.0061 16.8 4.8 0.0061 16.8 4.8 7.9 3 2 5 8 8 8 5 EB module Dickkopf_N PF04706.12 EGC28838.1 - 0.2 12.2 80.8 0.1 13.1 3.9 7.2 4 3 2 6 6 6 0 Dickkopf N-terminal cysteine-rich region Dickkopf_N PF04706.12 EGC28839.1 - 0.0066 16.9 11.2 0.0066 16.9 11.2 6.5 3 3 2 5 5 5 2 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGC28839.1 - 0.023 15.0 4.9 0.023 15.0 4.9 6.6 1 1 4 5 5 5 0 EB module FNIP PF05725.12 EGC28840.1 - 2.3e-64 213.3 44.8 4.3e-13 49.2 0.7 8.9 5 2 5 10 10 10 10 FNIP Repeat F-box-like_2 PF13013.6 EGC28840.1 - 0.0092 15.9 0.7 0.77 9.8 0.0 3.3 2 1 1 3 3 3 1 F-box-like domain DUF3752 PF12572.8 EGC28841.1 - 9.6e-10 39.2 6.6 9.6e-10 39.2 6.6 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3752) Vma12 PF11712.8 EGC28841.1 - 0.057 13.5 0.0 0.15 12.1 0.0 1.8 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase CAAD PF14159.6 EGC28842.1 - 0.84 9.5 9.5 0.06 13.2 2.3 2.5 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1282 PF06930.12 EGC28842.1 - 0.93 9.2 10.6 0.042 13.6 1.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1282) DUF2207 PF09972.9 EGC28842.1 - 1.1 8.0 10.9 0.35 9.6 5.7 2.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Claudin_2 PF13903.6 EGC28842.1 - 1.5 8.5 15.7 14 5.4 12.5 2.9 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2721 PF11026.8 EGC28842.1 - 3.7 7.4 11.0 0.1 12.5 1.9 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) Saf_2TM PF18303.1 EGC28842.1 - 4 7.0 8.5 0.97 9.0 0.1 3.3 3 1 1 4 4 4 0 SAVED-fused 2TM effector domain Cation_efflux PF01545.21 EGC28843.1 - 0.00058 19.6 3.9 0.0023 17.7 0.9 2.4 2 1 0 2 2 2 1 Cation efflux family Claudin_2 PF13903.6 EGC28843.1 - 0.004 16.9 1.3 0.004 16.9 1.3 2.4 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.20 EGC28843.1 - 0.016 15.1 6.9 0.78 9.6 1.0 2.3 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF202 PF02656.15 EGC28843.1 - 0.02 15.3 3.7 1.2 9.6 0.4 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF202) DUF3341 PF11821.8 EGC28843.1 - 0.02 14.5 2.0 0.17 11.5 0.0 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3341) GSG-1 PF07803.11 EGC28843.1 - 0.063 13.2 0.0 0.23 11.4 0.1 1.9 2 0 0 2 2 2 0 GSG1-like protein Baculo_p74 PF04583.12 EGC28843.1 - 0.087 12.3 5.3 0.2 11.1 1.9 2.2 2 0 0 2 2 2 0 Baculoviridae p74 conserved region DUF2768 PF10966.8 EGC28843.1 - 0.9 10.0 11.9 1.1 9.8 0.7 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2768) Cation_ATPase_C PF00689.21 EGC28843.1 - 2.7 7.7 16.5 0.63 9.7 3.9 2.4 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus RRM_1 PF00076.22 EGC28844.1 - 6.9e-19 67.4 0.8 1.1e-18 66.8 0.8 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC28844.1 - 0.027 14.6 0.0 0.063 13.4 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 EGC28844.1 - 0.028 14.0 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) NDUF_B4 PF07225.12 EGC28845.1 - 0.19 11.6 1.9 1.4 8.8 0.7 2.3 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PTPlike_phytase PF14566.6 EGC28845.1 - 2.9 8.0 11.7 0.78 9.9 5.3 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate Band_7 PF01145.25 EGC28846.1 - 3e-25 89.3 2.7 4e-25 88.8 2.7 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGC28846.1 - 0.00066 18.8 1.7 0.00085 18.5 1.7 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial SnoaL_2 PF12680.7 EGC28847.1 - 7e-06 26.6 0.0 7.9e-06 26.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC28847.1 - 0.00057 19.7 0.1 0.0022 17.8 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 EGC28847.1 - 0.023 15.1 0.0 0.026 14.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3271 PF11675.8 EGC28847.1 - 0.04 13.2 0.3 0.043 13.1 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) Pkinase_Tyr PF07714.17 EGC28848.1 - 1.6e-88 296.4 0.0 1.5e-59 201.4 0.0 2.5 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGC28848.1 - 1.9e-66 224.1 0.0 5.2e-47 160.4 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.6 EGC28848.1 - 0.0001 21.7 0.0 0.15 11.4 0.0 2.5 2 0 0 2 2 2 2 Kinase-like Kdo PF06293.14 EGC28848.1 - 0.00076 18.9 0.1 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family DUF1664 PF07889.12 EGC28848.1 - 0.69 10.0 2.7 1.4 9.0 1.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF4404 PF14357.6 EGC28848.1 - 2.2 9.0 10.4 0.046 14.4 1.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) CH PF00307.31 EGC28849.1 - 8.7e-15 54.8 0.1 8.7e-15 54.8 0.1 3.5 5 1 1 6 6 6 1 Calponin homology (CH) domain GAS2 PF02187.17 EGC28849.1 - 5.2e-11 42.5 0.0 1.9e-10 40.6 0.0 2.0 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain Secretin_N_2 PF07655.13 EGC28850.1 - 0.00089 19.7 22.3 0.033 14.7 3.9 2.6 2 0 0 2 2 2 2 Secretin N-terminal domain CHZ PF09649.10 EGC28851.1 - 0.049 13.1 2.0 0.18 11.3 2.0 2.0 1 0 0 1 1 1 0 Histone chaperone domain CHZ TIG PF01833.24 EGC28852.1 - 4e-13 49.2 42.5 8.2e-06 25.8 0.9 7.1 7 0 0 7 7 7 5 IPT/TIG domain Limkain-b1 PF11608.8 EGC28852.1 - 0.023 14.8 0.1 2.6 8.2 0.0 2.7 3 0 0 3 3 3 0 Limkain b1 Tudor_2 PF18104.1 EGC28852.1 - 0.061 13.0 0.5 17 5.2 0.1 2.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TerB_C PF15615.6 EGC28853.1 - 0.049 13.9 0.1 0.049 13.9 0.1 1.0 1 0 0 1 1 1 0 TerB-C domain Ras PF00071.22 EGC28854.1 - 2.2e-64 216.0 0.9 2.5e-64 215.7 0.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28854.1 - 1.5e-35 122.0 0.1 2.5e-35 121.3 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC28854.1 - 1.3e-16 60.6 0.1 1.6e-16 60.3 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC28854.1 - 1.7e-05 24.3 0.1 2e-05 24.1 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC28854.1 - 2.9e-05 23.7 0.5 9.2e-05 22.1 0.4 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC28854.1 - 3.2e-05 23.9 1.1 0.14 12.0 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC28854.1 - 3.6e-05 23.8 0.0 5.7e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.29 EGC28854.1 - 6.9e-05 23.3 0.1 0.0077 16.7 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.10 EGC28854.1 - 0.00019 20.9 0.1 0.00031 20.2 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGC28854.1 - 0.0039 16.7 0.1 0.023 14.2 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGC28854.1 - 0.032 14.5 0.0 0.11 12.8 0.0 1.9 1 1 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGC28854.1 - 0.034 14.5 0.0 0.071 13.5 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_29 PF13555.6 EGC28854.1 - 0.039 13.7 0.1 0.16 11.8 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGC28854.1 - 0.043 13.3 0.1 0.29 10.6 0.0 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_5 PF07728.14 EGC28854.1 - 0.043 13.8 0.0 0.065 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EGC28854.1 - 0.06 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein MMADHC PF10229.9 EGC28855.1 - 7.8e-29 101.3 0.6 2.3e-28 99.7 0.6 1.6 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type D protein GrpE PF01025.19 EGC28856.1 - 4.4e-32 111.0 15.3 1.5e-30 106.0 15.3 2.0 1 1 0 1 1 1 1 GrpE SPATA1_C PF15743.5 EGC28856.1 - 0.036 14.2 10.5 0.049 13.7 10.5 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated C-terminus DASH_Hsk3 PF08227.11 EGC28856.1 - 0.13 12.7 1.0 1 9.8 0.0 2.6 3 0 0 3 3 3 0 DASH complex subunit Hsk3 like DUF4286 PF14114.6 EGC28856.1 - 0.14 12.6 2.4 0.25 11.8 1.3 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) DUF5320 PF17253.2 EGC28856.1 - 0.65 11.1 2.9 0.39 11.8 0.5 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF2031 PF09592.10 EGC28856.1 - 0.66 9.4 8.8 0.88 9.0 8.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2031) DUF4085 PF13315.6 EGC28856.1 - 3.2 7.3 10.7 2.6 7.6 5.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) RIC3 PF15361.6 EGC28856.1 - 6.3 7.2 10.4 6.1 7.2 3.6 2.3 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 EF-hand_7 PF13499.6 EGC28857.1 - 7.7e-21 74.3 7.8 9.6e-10 38.8 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGC28857.1 - 1.1e-19 68.4 5.6 0.00049 19.4 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGC28857.1 - 1.5e-19 68.1 3.4 0.00025 20.7 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC28857.1 - 1.2e-15 56.2 4.5 4.8e-05 22.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGC28857.1 - 1.9e-11 43.6 3.2 6.2e-06 26.0 0.9 3.4 3 0 0 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC28857.1 - 1.4e-08 35.1 1.6 0.021 15.1 0.1 3.1 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Dimerisation PF08100.11 EGC28857.1 - 0.0017 18.3 0.2 2.4 8.2 0.0 3.1 1 1 2 3 3 3 2 Dimerisation domain EF-hand_10 PF14788.6 EGC28857.1 - 0.0023 17.7 0.9 4.1 7.4 0.0 3.1 2 1 1 3 3 3 2 EF hand Caleosin PF05042.13 EGC28857.1 - 0.0024 17.8 1.3 1.7 8.6 0.0 3.4 1 1 2 3 3 3 1 Caleosin related protein EF-hand_13 PF17958.1 EGC28857.1 - 0.017 14.9 0.3 16 5.3 0.0 3.4 2 1 1 3 3 3 0 EF-hand domain PMBR PF09373.10 EGC28857.1 - 0.066 13.4 0.2 32 4.9 0.0 4.0 4 1 1 5 5 5 0 Pseudomurein-binding repeat SpaA PF17802.1 EGC28857.1 - 0.43 10.9 2.1 4.1 7.8 1.2 2.1 1 1 1 2 2 2 0 Prealbumin-like fold domain Dockerin_1 PF00404.18 EGC28857.1 - 2 8.7 11.6 27 5.1 4.2 3.8 2 1 2 4 4 4 0 Dockerin type I domain Synaptobrevin PF00957.21 EGC28857.1 - 2.8 7.8 7.0 1.1 9.1 0.2 2.6 2 1 0 2 2 2 0 Synaptobrevin FNIP PF05725.12 EGC28858.1 - 6.4e-29 99.9 27.8 4.3e-06 26.8 0.2 8.8 4 2 5 10 10 10 8 FNIP Repeat zf-B_box PF00643.24 EGC28858.1 - 1.6e-05 25.0 3.6 2.6e-05 24.3 3.6 1.4 1 0 0 1 1 1 1 B-box zinc finger Pro_isomerase PF00160.21 EGC28858.1 - 0.027 14.7 0.0 54 4.0 0.0 4.8 6 0 0 6 6 6 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD YpjP PF14005.6 EGC28858.1 - 0.086 12.9 3.5 0.12 12.4 2.4 1.7 1 1 0 1 1 1 0 YpjP-like protein Orbi_NS3 PF01616.16 EGC28858.1 - 0.13 11.9 0.3 0.25 11.0 0.3 1.4 1 0 0 1 1 1 0 Orbivirus NS3 Ribosomal_S19 PF00203.21 EGC28858.1 - 0.14 12.1 0.0 0.39 10.6 0.0 1.7 1 0 0 1 1 1 0 Ribosomal protein S19 Alg6_Alg8 PF03155.15 EGC28859.1 - 3.4e-144 481.4 41.0 4.7e-144 481.0 41.0 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ank_2 PF12796.7 EGC28861.1 - 0.00026 21.5 3.7 0.063 13.9 0.1 4.3 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC28861.1 - 0.0039 17.7 1.9 0.24 12.0 0.1 3.8 4 0 0 4 4 4 1 Ankyrin repeats (many copies) Gti1_Pac2 PF09729.9 EGC28861.1 - 0.19 11.8 6.5 0.075 13.1 2.0 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Tim54 PF11711.8 EGC28861.1 - 0.51 9.1 4.6 0.99 8.1 4.6 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 SR-25 PF10500.9 EGC28861.1 - 1.1 8.8 7.1 2 8.0 7.1 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Cyclin_N PF00134.23 EGC28862.1 - 1.4e-19 70.1 0.2 1.9e-17 63.2 0.1 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC28862.1 - 2.5e-06 27.6 0.2 2.1e-05 24.6 0.1 2.1 2 0 0 2 2 2 1 Cyclin, C-terminal domain Cyclin_C_2 PF16899.5 EGC28862.1 - 0.011 16.1 0.1 0.036 14.4 0.0 1.8 1 1 1 2 2 2 0 Cyclin C-terminal domain TFIIB PF00382.19 EGC28862.1 - 0.015 15.3 0.0 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Transcription factor TFIIB repeat Prefoldin PF02996.17 EGC28864.1 - 3.2e-26 91.6 3.7 5.8e-26 90.8 3.7 1.4 1 0 0 1 1 1 1 Prefoldin subunit SIMPL PF04402.14 EGC28864.1 - 0.012 16.1 0.8 0.012 16.1 0.8 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF541) CdvA PF18822.1 EGC28864.1 - 0.028 14.3 6.1 0.3 10.9 2.5 2.9 2 1 0 2 2 2 0 CdvA-like coiled-coil domain Spore_II_R PF09551.10 EGC28864.1 - 0.73 10.3 6.0 2.8 8.4 2.2 2.2 1 1 1 2 2 2 0 Stage II sporulation protein R (spore_II_R) RIC3 PF15361.6 EGC28865.1 - 1.6 9.2 5.5 1.3 9.4 0.7 2.4 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 APH PF01636.23 EGC28866.1 - 5e-14 52.8 0.0 7.3e-14 52.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGC28866.1 - 0.0087 15.3 0.0 0.012 14.8 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase RRM_1 PF00076.22 EGC28866.1 - 0.033 14.0 0.1 0.13 12.1 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PfaD_N PF18328.1 EGC28866.1 - 0.047 13.6 0.6 0.78 9.7 0.0 2.4 2 0 0 2 2 2 0 Fatty acid synthase subunit PfaD N-terminal domain zf-CSL PF05207.13 EGC28867.1 - 1.3e-20 72.9 4.7 2.3e-20 72.0 4.7 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EGC28867.1 - 1.1e-17 63.9 4.3 2.2e-17 62.9 4.3 1.5 1 1 0 1 1 1 1 DnaJ domain SNF2_N PF00176.23 EGC28868.1 - 1.9e-73 247.2 0.0 5.5e-73 245.7 0.0 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.10 EGC28868.1 - 8.8e-41 138.5 5.8 8.8e-41 138.5 5.8 3.6 4 0 0 4 4 4 1 SLIDE Helicase_C PF00271.31 EGC28868.1 - 2.1e-20 73.1 0.0 1.8e-19 70.1 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HAND PF09110.11 EGC28868.1 - 4.5e-13 49.9 7.1 4.5e-13 49.9 7.1 4.5 4 1 1 5 5 3 1 HAND Myb_DNA-binding PF00249.31 EGC28868.1 - 7.7e-11 42.0 0.1 6.7e-06 26.2 0.0 3.1 2 0 0 2 2 2 2 Myb-like DNA-binding domain HDA2-3 PF11496.8 EGC28868.1 - 7.2e-10 38.5 0.0 7.2e-10 38.5 0.0 2.8 3 1 0 3 3 3 1 Class II histone deacetylase complex subunits 2 and 3 ResIII PF04851.15 EGC28868.1 - 7.9e-09 35.7 0.0 7.9e-09 35.7 0.0 3.4 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC28868.1 - 5.4e-06 26.3 0.3 2.8e-05 24.0 0.0 2.4 3 0 0 3 3 3 1 DEAD/DEAH box helicase TMEM132 PF16070.5 EGC28868.1 - 0.18 11.1 0.8 0.31 10.3 0.8 1.3 1 0 0 1 1 1 0 Transmembrane protein family 132 AAA_22 PF13401.6 EGC28868.1 - 0.19 12.0 1.0 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGC28868.1 - 0.23 11.5 4.0 0.73 9.9 0.0 3.1 3 0 0 3 3 3 0 AAA domain RCC1 PF00415.18 EGC28869.1 - 4.1e-44 149.0 1.1 9.8e-10 38.9 0.0 5.8 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC28869.1 - 2e-27 94.4 21.4 1.7e-07 30.8 0.3 5.4 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.6 EGC28869.1 - 7.9e-11 42.3 0.1 4.9e-07 30.2 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC28869.1 - 4e-09 36.6 0.0 8.7e-09 35.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC28869.1 - 2.9e-07 31.0 0.1 1.5e-06 28.7 0.1 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC28869.1 - 8.7e-06 25.7 0.0 9.3e-05 22.5 0.0 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGC28869.1 - 0.00015 22.1 0.0 0.0026 18.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Guanylate_cyc PF00211.20 EGC28870.1 - 7.2e-73 244.1 0.3 8.4e-44 149.4 0.1 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF3278 PF11683.8 EGC28870.1 - 0.0057 16.7 4.0 0.0057 16.7 4.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF3278) DnaJ PF00226.31 EGC28870.1 - 0.036 14.2 0.9 0.11 12.6 0.9 1.9 1 0 0 1 1 1 0 DnaJ domain TRIQK PF15168.6 EGC28870.1 - 0.082 12.8 3.5 0.48 10.4 2.7 2.9 1 1 0 1 1 1 0 Triple QxxK/R motif-containing protein family DUF483 PF04467.12 EGC28870.1 - 0.086 12.8 1.9 0.11 12.5 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF483) EGF_2 PF07974.13 EGC28871.1 - 0.00036 20.8 47.1 0.2 12.1 10.6 3.9 3 0 0 3 3 3 3 EGF-like domain PAP_assoc PF03828.19 EGC28871.1 - 0.0034 17.6 1.3 0.015 15.5 0.2 2.7 2 0 0 2 2 2 1 Cid1 family poly A polymerase TIG PF01833.24 EGC28871.1 - 0.0076 16.3 9.6 0.01 15.9 0.8 4.2 4 0 0 4 4 4 1 IPT/TIG domain NTP_transf_2 PF01909.23 EGC28871.1 - 0.008 16.4 0.1 0.042 14.1 0.1 2.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain Csm2_III-A PF03750.13 EGC28871.1 - 0.012 16.5 2.5 1.9 9.3 0.1 2.8 2 0 0 2 2 2 0 Csm2 Type III-A CDK2AP PF09806.9 EGC28871.1 - 0.041 13.9 0.0 0.077 13.1 0.0 1.3 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein Laminin_EGF PF00053.24 EGC28871.1 - 0.054 13.6 30.1 3.9 7.7 3.8 3.7 2 1 1 3 3 3 0 Laminin EGF domain MetOD2 PF18548.1 EGC28871.1 - 0.57 10.3 3.9 1.6 8.9 0.3 2.7 2 0 0 2 2 2 0 Metanogen output domain 2 Sec2p PF06428.11 EGC28871.1 - 1.6 8.8 11.6 0.21 11.6 0.4 3.4 4 0 0 4 4 4 0 GDP/GTP exchange factor Sec2p YabA PF06156.13 EGC28871.1 - 4.5 8.0 10.2 5.1 7.8 1.2 3.2 3 0 0 3 3 2 0 Initiation control protein YabA FlxA PF14282.6 EGC28871.1 - 7.3 6.6 8.9 13 5.9 1.1 2.5 2 0 0 2 2 2 0 FlxA-like protein Ctf8 PF09696.10 EGC28872.1 - 6.1e-08 33.1 0.2 3e-06 27.6 0.1 2.3 1 1 1 2 2 2 2 Ctf8 TipE PF16972.5 EGC28872.1 - 0.24 10.5 5.0 0.3 10.2 5.0 1.1 1 0 0 1 1 1 0 Na+ channel auxiliary subunit TipE CTP_transf_like PF01467.26 EGC28873.1 - 8.5e-15 55.2 0.0 1e-14 54.9 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase-like Enolase_C PF00113.22 EGC28876.1 - 4.3e-90 302.0 0.2 4.6e-90 301.8 0.2 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MR_MLE_C PF13378.6 EGC28876.1 - 3.8e-08 33.2 0.0 4.3e-08 33.0 0.0 1.1 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGC28876.1 - 2.3e-05 23.7 0.0 3.3e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus Coiled PF05710.12 EGC28877.1 - 0.001 19.8 16.1 0.0012 19.6 16.1 1.1 1 0 0 1 1 1 1 Coiled coil Nipped-B_C PF12830.7 EGC28878.1 - 1.2e-41 142.7 0.9 1.2e-41 142.7 0.9 5.0 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.7 EGC28878.1 - 2.5e-12 46.8 2.1 9.9e-11 41.7 0.4 3.5 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT PF02985.22 EGC28878.1 - 1.3e-05 25.0 0.1 17 6.0 0.0 6.5 7 0 0 7 7 7 1 HEAT repeat HEAT_2 PF13646.6 EGC28878.1 - 0.00065 20.0 0.0 0.73 10.3 0.0 3.2 2 1 1 3 3 3 2 HEAT repeats Cnd1 PF12717.7 EGC28878.1 - 0.00068 19.7 0.1 0.00068 19.7 0.1 7.7 8 2 2 10 10 10 3 non-SMC mitotic condensation complex subunit 1 DUF4042 PF13251.6 EGC28878.1 - 0.17 11.6 5.4 3.2 7.4 0.0 4.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4042) PHD PF00628.29 EGC28878.1 - 1.6 8.6 15.2 18 5.3 15.2 2.4 1 1 0 1 1 1 0 PHD-finger EF-hand_7 PF13499.6 EGC28880.1 - 6.5e-10 39.3 3.8 6.6e-05 23.3 3.0 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC28880.1 - 3e-09 36.1 7.5 0.00083 19.1 0.3 5.0 4 1 1 5 5 5 2 EF-hand domain EF-hand_1 PF00036.32 EGC28880.1 - 1.2e-06 27.7 18.3 8.6e-06 24.9 0.4 5.6 6 1 0 6 6 6 2 EF hand EF-hand_8 PF13833.6 EGC28880.1 - 4.4e-06 26.4 9.8 0.00013 21.7 3.5 3.5 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_4 PF12763.7 EGC28880.1 - 0.00047 20.1 1.0 0.16 12.0 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.6 EGC28880.1 - 0.043 13.3 0.4 0.043 13.3 0.4 4.1 5 0 0 5 5 5 0 EF hand EF-hand_9 PF14658.6 EGC28880.1 - 0.064 13.6 0.1 0.39 11.1 0.0 2.4 3 0 0 3 3 3 0 EF-hand domain SinI PF08671.10 EGC28880.1 - 4.5 7.1 6.6 5.6 6.9 0.3 3.4 4 0 0 4 4 4 0 Anti-repressor SinI Eapp_C PF10238.9 EGC28881.1 - 0.098 12.7 3.6 0.099 12.7 3.6 1.1 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF4770 PF15994.5 EGC28881.1 - 0.26 11.5 8.0 0.29 11.4 8.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4770) SUIM_assoc PF16619.5 EGC28881.1 - 0.4 10.8 11.8 0.62 10.2 11.8 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 CMS1 PF14617.6 EGC28881.1 - 0.82 9.0 5.8 1 8.6 5.8 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Connexin PF00029.19 EGC28881.1 - 0.92 9.2 3.0 0.87 9.3 3.0 1.1 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC28881.1 - 1.6 7.4 3.9 1.6 7.5 3.9 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_S49_N PF08496.10 EGC28881.1 - 2.1 8.4 7.1 2.8 8.0 7.1 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal BAR PF03114.18 EGC28883.1 - 1.3e-15 57.7 13.5 2.7e-15 56.7 13.5 1.4 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGC28883.1 - 3.4e-14 52.2 0.0 6.1e-14 51.4 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC28883.1 - 1.5e-13 50.4 0.0 2.5e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC28883.1 - 3.3e-11 42.7 0.0 5.3e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SATase_N PF06426.14 EGC28883.1 - 0.056 13.8 0.4 0.72 10.3 0.0 2.2 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal TAA-Trp-ring PF15401.6 EGC28883.1 - 0.2 12.1 3.4 2 8.9 0.1 3.0 3 0 0 3 3 3 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin DUF4164 PF13747.6 EGC28883.1 - 1.3 9.3 8.0 0.59 10.5 0.1 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF4164) Lge1 PF11488.8 EGC28883.1 - 5.9 7.1 8.0 18 5.6 0.9 2.9 2 1 0 2 2 2 0 Transcriptional regulatory protein LGE1 Rpr2 PF04032.16 EGC28884.1 - 5.1e-08 33.1 6.5 5.1e-08 33.1 6.5 3.2 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain ERM PF00769.19 EGC28885.1 - 0.0033 17.3 12.8 0.0033 17.3 12.8 2.2 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.12 EGC28885.1 - 0.039 14.0 38.0 0.042 13.9 21.5 2.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein KASH_CCD PF14662.6 EGC28885.1 - 0.053 13.4 37.2 0.074 12.9 37.2 1.2 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH DUF2353 PF09789.9 EGC28885.1 - 0.089 12.1 32.4 0.017 14.5 24.4 2.1 1 1 1 2 2 2 0 Uncharacterized coiled-coil protein (DUF2353) DUF724 PF05266.14 EGC28885.1 - 0.45 10.3 24.7 0.067 13.0 20.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Phage_GPO PF05929.11 EGC28885.1 - 0.51 9.9 19.0 0.82 9.2 19.0 1.3 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase THOC7 PF05615.13 EGC28885.1 - 0.57 10.5 31.3 1.2 9.4 9.0 2.1 1 1 1 2 2 2 0 Tho complex subunit 7 Jnk-SapK_ap_N PF09744.9 EGC28885.1 - 0.67 10.2 38.8 7.2 6.8 11.8 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Macoilin PF09726.9 EGC28885.1 - 1.2 7.6 24.5 1.7 7.1 24.5 1.2 1 0 0 1 1 1 0 Macoilin family FAM76 PF16046.5 EGC28885.1 - 1.3 8.3 24.3 1.7 7.9 24.3 1.1 1 0 0 1 1 1 0 FAM76 protein CAMP_factor PF07373.11 EGC28885.1 - 1.4 8.5 15.4 4.7 6.8 9.4 2.3 1 1 1 2 2 2 0 CAMP factor (Cfa) Het-C PF07217.11 EGC28885.1 - 1.6 7.2 15.6 2 6.9 15.6 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C Peptidase_S46 PF10459.9 EGC28885.1 - 1.8 7.1 18.6 2 7.0 18.6 1.0 1 0 0 1 1 1 0 Peptidase S46 Seryl_tRNA_N PF02403.22 EGC28885.1 - 2.3 8.5 33.3 13 6.1 19.2 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Laminin_II PF06009.12 EGC28885.1 - 2.3 8.2 32.5 7.5 6.6 6.3 2.8 1 1 2 3 3 3 0 Laminin Domain II DUF812 PF05667.11 EGC28885.1 - 2.5 6.9 36.9 5.4 5.8 36.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF812) DUF4407 PF14362.6 EGC28885.1 - 3.3 7.0 21.2 4.2 6.6 21.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YabA PF06156.13 EGC28885.1 - 3.3 8.4 30.5 0.25 12.0 17.5 2.4 1 1 1 2 2 2 0 Initiation control protein YabA APG6_N PF17675.1 EGC28885.1 - 6 7.4 40.2 3.3 8.3 33.8 2.2 1 1 1 2 2 2 0 Apg6 coiled-coil region EGF_2 PF07974.13 EGC28886.1 - 2.7 8.4 10.0 5.5 7.5 10.0 1.5 1 0 0 1 1 1 0 EGF-like domain Ras PF00071.22 EGC28887.1 - 2.2e-58 196.4 0.1 2.5e-58 196.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28887.1 - 3.7e-21 75.6 0.0 6.1e-21 74.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC28887.1 - 1.6e-09 37.5 0.0 1.9e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC28887.1 - 1.2e-05 25.0 0.2 3.7e-05 23.4 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGC28887.1 - 0.00048 19.4 0.2 0.18 10.9 0.1 2.1 1 1 0 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGC28887.1 - 0.00056 20.0 0.0 0.00076 19.5 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC28887.1 - 0.0012 18.7 1.7 0.87 9.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase MMR_HSR1_Xtn PF16897.5 EGC28887.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.4 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain Ric8 PF10165.9 EGC28888.1 - 1.1e-29 103.8 0.2 1.4e-28 100.2 0.0 2.0 1 1 1 2 2 2 2 Guanine nucleotide exchange factor synembryn SNARE_assoc PF09335.11 EGC28889.1 - 6.6e-14 52.4 1.3 6.6e-14 52.4 1.3 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein DDDD PF10161.9 EGC28889.1 - 7.9 6.3 7.8 0.59 9.9 0.4 2.9 3 0 0 3 3 3 0 Putative mitochondrial precursor protein CBM9_1 PF06452.11 EGC28890.1 - 0.00064 19.7 0.0 0.001 19.0 0.0 1.4 1 1 0 1 1 1 1 Carbohydrate family 9 binding domain-like Beta_helix PF13229.6 EGC28890.1 - 0.0099 15.7 2.2 0.017 15.0 2.2 1.3 1 0 0 1 1 1 1 Right handed beta helix region CBM9_2 PF16011.5 EGC28890.1 - 0.015 15.0 0.7 0.033 13.9 0.7 1.6 1 1 0 1 1 1 0 Carbohydrate-binding family 9 E1_UFD PF09358.10 EGC28891.1 - 0.015 16.0 0.1 0.018 15.7 0.1 1.0 1 0 0 1 1 1 0 Ubiquitin fold domain Elong_Iki1 PF10483.9 EGC28892.1 - 0.069 12.6 0.6 0.079 12.5 0.6 1.0 1 0 0 1 1 1 0 Elongator subunit Iki1 DUF1639 PF07797.14 EGC28893.1 - 1.4 9.0 4.0 2.5 8.2 4.0 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1639) Mito_carr PF00153.27 EGC28894.1 - 2.8e-69 229.1 3.0 1.4e-23 82.6 0.1 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein GMC_oxred_N PF00732.19 EGC28895.1 - 5.8e-41 140.8 0.8 8.9e-41 140.2 0.3 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGC28895.1 - 9.2e-22 78.1 0.1 2.1e-20 73.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase FAD_binding_2 PF00890.24 EGC28895.1 - 3.4e-08 33.0 0.2 5.1e-07 29.1 0.4 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGC28895.1 - 3.1e-07 30.3 2.2 8.5e-06 25.6 2.2 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC28895.1 - 3.8e-06 27.0 0.1 9.8e-06 25.7 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGC28895.1 - 0.00023 20.5 0.3 0.0013 18.0 0.2 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGC28895.1 - 0.0011 18.3 0.7 0.0017 17.7 0.7 1.2 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGC28895.1 - 0.0013 18.0 0.3 0.0025 17.1 0.3 1.3 1 0 0 1 1 1 1 Thi4 family HI0933_like PF03486.14 EGC28895.1 - 0.008 14.9 1.2 0.016 13.9 1.2 1.5 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.12 EGC28895.1 - 0.018 14.1 0.1 0.028 13.5 0.1 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein ApbA PF02558.16 EGC28895.1 - 0.068 12.8 0.4 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.6 EGC28895.1 - 0.083 12.1 0.0 0.36 10.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGC28895.1 - 1.3 8.3 2.9 2.2 7.5 2.9 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Anti-TRAP PF15777.5 EGC28896.1 - 0.17 11.9 1.0 0.34 10.9 1.0 1.4 1 0 0 1 1 1 0 Tryptophan RNA-binding attenuator protein inhibitory protein Tox-URI2 PF15653.6 EGC28896.1 - 2.5 8.4 8.2 7.3 6.9 0.8 3.0 2 1 1 3 3 3 0 URI fold toxin 2 DUF678 PF05077.12 EGC28896.1 - 4.8 7.4 9.5 7.1 6.8 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF678) EGF_2 PF07974.13 EGC28897.1 - 4.3e-10 39.8 46.6 7e-05 23.1 8.8 3.7 2 1 1 3 3 3 3 EGF-like domain TIG PF01833.24 EGC28897.1 - 5.6e-07 29.6 20.0 0.0024 17.9 4.2 4.5 4 0 0 4 4 4 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC28897.1 - 0.37 11.0 42.8 0.38 10.9 10.1 3.6 2 1 1 3 3 3 0 Laminin EGF domain zf-CCCH_7 PF18586.1 EGC28897.1 - 0.41 11.0 7.6 5.7 7.4 0.5 3.9 3 1 1 4 4 4 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 LRR_1 PF00560.33 EGC28897.1 - 4 8.4 11.2 89 4.3 2.1 5.8 3 1 0 3 3 3 0 Leucine Rich Repeat CBM49 PF09478.10 EGC28898.1 - 1e-16 61.0 0.1 1.5e-16 60.4 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGC28898.1 - 0.012 15.9 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Cellulose binding domain Fungus-induced PF10917.8 EGC28898.1 - 0.041 14.2 0.2 0.082 13.2 0.2 1.5 1 0 0 1 1 1 0 Fungus-induced protein CAF1A PF12253.8 EGC28900.1 - 3.5e-22 78.4 14.7 3.5e-22 78.4 14.7 5.9 3 2 1 4 4 4 1 Chromatin assembly factor 1 subunit A ADK PF00406.22 EGC28901.1 - 3.8e-11 43.3 0.5 1.4e-10 41.5 0.1 2.3 1 1 1 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EGC28901.1 - 3.8e-05 24.1 0.1 0.00015 22.2 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC28901.1 - 0.17 12.4 0.4 0.84 10.2 0.1 2.4 2 1 0 2 2 2 0 AAA domain FNIP PF05725.12 EGC28903.1 - 1.8e-33 114.4 49.1 3.1e-08 33.6 0.2 9.5 5 2 7 13 13 13 11 FNIP Repeat Baculo_LEF-10 PF07206.11 EGC28903.1 - 1.9 8.7 6.6 4.2 7.6 6.6 1.5 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) Aldedh PF00171.22 EGC28904.1 - 1.2e-134 449.4 0.3 1.3e-134 449.2 0.3 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LZ3wCH PF18517.1 EGC28904.1 - 0.24 11.5 2.6 0.2 11.8 0.6 1.9 2 0 0 2 2 2 0 Leucine zipper with capping helix domain Pkinase_Tyr PF07714.17 EGC28906.1 - 7.2e-21 74.6 0.0 9.4e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC28906.1 - 8.4e-15 54.8 0.0 1.1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGC28906.1 - 0.071 12.4 0.1 0.11 11.7 0.1 1.5 1 1 0 1 1 1 0 Kinase-like SPATA24 PF15175.6 EGC28907.1 - 0.0022 17.9 7.9 0.0022 17.9 7.9 4.3 1 1 3 4 4 4 1 Spermatogenesis-associated protein 24 Cep57_CLD_2 PF14197.6 EGC28907.1 - 0.008 16.2 0.8 0.008 16.2 0.8 6.2 4 2 1 5 5 5 1 Centrosome localisation domain of PPC89 KELK PF15796.5 EGC28907.1 - 0.0086 16.5 4.6 0.0086 16.5 4.6 5.9 1 1 4 6 6 6 1 KELK-motif containing domain of MRCK Ser/Thr protein kinase KASH_CCD PF14662.6 EGC28907.1 - 0.013 15.3 1.1 0.013 15.3 1.1 5.0 2 1 3 5 5 5 0 Coiled-coil region of CCDC155 or KASH SlyX PF04102.12 EGC28907.1 - 0.04 14.5 0.8 0.04 14.5 0.8 6.4 2 2 5 7 7 7 0 SlyX LSM14 PF12701.7 EGC28907.1 - 0.59 10.3 4.7 0.64 10.2 0.0 3.3 4 0 0 4 4 4 0 Scd6-like Sm domain DUF4236 PF14020.6 EGC28907.1 - 1.2 9.7 3.4 33 5.1 2.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4236) Baculo_PEP_C PF04513.12 EGC28907.1 - 9 6.3 23.3 0.16 12.0 0.9 4.8 1 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus PhoLip_ATPase_C PF16212.5 EGC28908.1 - 1.3e-78 264.2 27.2 1.3e-78 264.2 27.2 2.6 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC28908.1 - 2.1e-25 88.2 2.5 2.1e-25 88.2 2.5 2.8 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGC28908.1 - 6.1e-12 45.4 0.0 6.1e-12 45.4 0.0 4.2 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGC28908.1 - 3.3e-08 34.1 0.2 0.0016 18.8 0.1 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGC28908.1 - 1e-07 31.9 0.0 3.8e-07 30.1 0.0 1.9 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGC28908.1 - 0.0079 16.0 0.3 0.037 13.8 0.0 2.2 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase RRM_1 PF00076.22 EGC28909.1 - 5.6e-13 48.5 0.8 1.2e-12 47.4 0.8 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC28909.1 - 3.1e-06 26.8 0.0 7.1e-06 25.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G8 PF10162.9 EGC28910.1 - 3.9e-26 91.5 3.2 1e-25 90.2 0.1 3.2 3 1 0 3 3 3 1 G8 domain T4_deiodinase PF00837.17 EGC28911.1 - 5.2e-22 78.3 0.0 6.8e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase Trypan_PARP PF05887.11 EGC28912.1 - 0.046 13.7 8.4 0.049 13.6 8.4 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pterin_bind PF00809.22 EGC28913.1 - 0.0095 15.6 0.0 0.012 15.3 0.0 1.1 1 0 0 1 1 1 1 Pterin binding enzyme TraO PF10626.9 EGC28913.1 - 0.15 11.8 0.9 0.3 10.9 0.6 1.6 1 1 1 2 2 2 0 Conjugative transposon protein TraO Babuvirus_MP PF07234.11 EGC28913.1 - 0.16 12.2 0.1 0.19 11.9 0.1 1.2 1 0 0 1 1 1 0 Movement and RNA silencing protein OTU PF02338.19 EGC28914.1 - 5.6e-12 46.3 0.0 1.8e-11 44.6 0.0 1.9 1 0 0 1 1 1 1 OTU-like cysteine protease CDC37_M PF08565.11 EGC28914.1 - 2.7 7.9 13.5 7.6 6.5 0.5 3.5 1 1 1 3 3 3 0 Cdc37 Hsp90 binding domain PA14 PF07691.12 EGC28915.1 - 1.1e-09 38.3 0.3 1.6e-09 37.8 0.3 1.3 1 0 0 1 1 1 1 PA14 domain HNH_3 PF13392.6 EGC28916.1 - 3.6e-12 45.9 3.6 3.6e-12 45.9 3.6 1.7 2 0 0 2 2 2 1 HNH endonuclease zf-CCHC_5 PF14787.6 EGC28916.1 - 3.4e-08 33.0 0.5 7.2e-08 32.0 0.5 1.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 EGC28916.1 - 0.00033 20.6 2.0 0.00061 19.7 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle I_LWEQ PF01608.17 EGC28919.1 - 0.00098 19.4 6.6 0.68 10.2 0.3 3.4 2 1 0 2 2 2 2 I/LWEQ domain WCCH PF03716.14 EGC28920.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif G-alpha PF00503.20 EGC28923.1 - 1.6e-100 336.7 12.7 2.1e-100 336.3 12.7 1.1 1 0 0 1 1 1 1 G-protein alpha subunit PH PF00169.29 EGC28923.1 - 3.7e-12 46.7 0.1 1.3e-11 44.9 0.1 2.0 1 0 0 1 1 1 1 PH domain Arf PF00025.21 EGC28923.1 - 5.8e-11 42.2 1.4 3.2e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC28923.1 - 0.00018 21.7 0.2 0.22 11.7 0.0 3.1 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase PH_8 PF15409.6 EGC28923.1 - 0.00045 20.4 0.3 0.0025 18.1 0.3 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Gtr1_RagA PF04670.12 EGC28923.1 - 0.00085 18.7 5.7 0.0042 16.5 0.2 3.0 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region PH_13 PF16652.5 EGC28923.1 - 0.0044 16.8 0.6 0.014 15.2 0.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGC28923.1 - 0.0081 16.6 4.4 0.016 15.6 0.3 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain TniB PF05621.11 EGC28923.1 - 0.014 14.8 0.1 0.026 14.0 0.1 1.4 1 0 0 1 1 1 0 Bacterial TniB protein GTP_EFTU PF00009.27 EGC28923.1 - 0.1 12.1 1.0 2.4 7.6 0.0 3.0 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain PPTA PF01239.22 EGC28924.1 - 1.1e-21 75.8 16.6 2.8e-07 30.0 1.7 6.6 7 0 0 7 7 7 4 Protein prenyltransferase alpha subunit repeat SbcD_C PF12320.8 EGC28924.1 - 0.079 13.3 0.1 0.22 11.8 0.0 1.7 2 0 0 2 2 2 0 Type 5 capsule protein repressor C-terminal domain S10_plectin PF03501.15 EGC28924.1 - 0.11 12.5 1.5 0.26 11.4 0.6 2.1 2 0 0 2 2 2 0 Plectin/S10 domain UVR PF02151.19 EGC28925.1 - 1.9e-05 24.3 3.4 1.9e-05 24.3 3.4 4.8 5 0 0 5 5 5 1 UvrB/uvrC motif DHR10 PF18595.1 EGC28925.1 - 0.0061 16.6 6.8 0.0061 16.6 6.8 7.1 4 2 3 8 8 8 2 Designed helical repeat protein 10 domain Dimer_Tnp_hAT PF05699.14 EGC28927.1 - 2.1e-16 59.5 0.4 5.7e-16 58.1 0.4 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4413 PF14372.6 EGC28927.1 - 0.017 15.5 5.8 0.017 15.5 1.9 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) RNase_E_G PF10150.9 EGC28927.1 - 0.1 12.0 2.1 0.17 11.2 2.1 1.3 1 0 0 1 1 1 0 Ribonuclease E/G family Glyco_hydro_101 PF12905.7 EGC28928.1 - 0.094 12.1 0.1 0.16 11.4 0.0 1.4 2 0 0 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase RED_N PF07808.13 EGC28932.1 - 2.5e-06 27.2 1.0 4.6e-06 26.4 0.0 1.7 1 1 1 2 2 2 1 RED-like protein N-terminal region SDP_N PF12278.8 EGC28933.1 - 4.3 7.5 9.6 12 6.0 9.5 1.8 1 1 0 1 1 1 0 Sex determination protein N terminal Histone PF00125.24 EGC28934.1 - 1.1e-49 168.1 1.7 1.3e-49 167.9 1.7 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 PAF PF15715.5 EGC28934.1 - 6.3e-06 26.8 0.6 7.5e-06 26.6 0.6 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain CENP-T_C PF15511.6 EGC28934.1 - 2.3e-05 24.4 0.2 3.9e-05 23.7 0.2 1.4 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC28934.1 - 0.00032 21.0 0.1 0.0005 20.4 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein HisKA PF00512.25 EGC28934.1 - 0.0092 16.0 0.2 0.016 15.2 0.2 1.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain TFIID-31kDa PF02291.15 EGC28934.1 - 0.019 15.0 0.1 0.031 14.3 0.1 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit INTS2 PF14750.6 EGC28935.1 - 2.1e-147 492.5 41.1 6.9e-138 461.0 30.1 2.1 1 1 1 2 2 2 2 Integrator complex subunit 2 RPW8 PF05659.11 EGC28935.1 - 1.7 8.4 7.5 0.088 12.5 1.1 2.2 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 CBM49 PF09478.10 EGC28936.1 - 2.4e-22 79.0 1.5 2.4e-22 79.0 1.5 1.6 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 DUF3316 PF11777.8 EGC28936.1 - 0.0081 16.2 1.6 0.011 15.8 1.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3316) Comm PF15957.5 EGC28936.1 - 0.018 15.4 1.6 0.03 14.7 1.6 1.7 1 1 0 1 1 1 0 Commissureless Serinc PF03348.15 EGC28936.1 - 0.023 13.7 0.8 0.025 13.5 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF4834 PF16118.5 EGC28936.1 - 0.026 15.5 1.2 0.034 15.1 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Bap31 PF05529.12 EGC28936.1 - 0.09 12.6 0.2 0.14 12.0 0.2 1.2 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF2722 PF10846.8 EGC28936.1 - 0.21 10.5 9.4 0.23 10.4 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF2387 PF09526.10 EGC28936.1 - 0.35 11.0 3.9 3 8.1 2.2 2.2 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) Spt20 PF12090.8 EGC28936.1 - 1.6 8.3 17.3 2 7.9 17.3 1.1 1 0 0 1 1 1 0 Spt20 family Roughex PF06020.11 EGC28936.1 - 2.1 7.4 6.3 2.4 7.2 6.3 1.1 1 0 0 1 1 1 0 Drosophila roughex protein Aminotran_1_2 PF00155.21 EGC28937.1 - 1.5e-14 54.0 0.0 1.8e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ras PF00071.22 EGC28938.1 - 3.5e-53 179.5 0.0 4.6e-53 179.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC28938.1 - 4.2e-19 68.9 0.0 9e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC28938.1 - 7.2e-07 28.8 0.0 9.1e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC28938.1 - 4.7e-05 22.9 0.1 6.5e-05 22.4 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC28938.1 - 0.0057 16.2 0.3 0.012 15.2 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC28938.1 - 0.0062 16.4 0.0 1 9.3 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EGC28938.1 - 0.02 14.7 3.1 0.096 12.4 2.9 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein PAG PF15347.6 EGC28938.1 - 0.024 13.7 0.4 0.031 13.3 0.4 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TniB PF05621.11 EGC28938.1 - 0.075 12.4 0.0 0.24 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein UCH PF00443.29 EGC28939.1 - 2.9e-13 49.9 30.5 1.3e-12 47.8 30.5 2.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Lin-8 PF03353.15 EGC28939.1 - 0.24 10.9 13.0 0.33 10.5 13.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Macoilin PF09726.9 EGC28939.1 - 1.1 7.8 13.6 1.2 7.7 13.6 1.2 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGC28939.1 - 2.2 7.0 10.7 3 6.5 10.7 1.2 1 0 0 1 1 1 0 Presenilin MOSP_N PF02707.16 EGC28942.1 - 0.051 13.3 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Major Outer Sheath Protein N-terminal region OTU PF02338.19 EGC28943.1 - 3.4e-10 40.5 5.5 6.6e-10 39.6 0.0 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease CPSF100_C PF13299.6 EGC28943.1 - 0.044 14.0 0.4 0.044 14.0 0.4 1.7 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal adh_short PF00106.25 EGC28943.1 - 0.19 11.2 0.8 0.77 9.2 0.3 1.9 2 0 0 2 2 2 0 short chain dehydrogenase DUF4407 PF14362.6 EGC28943.1 - 5 6.4 11.6 4.8 6.5 8.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) TFIIA PF03153.13 EGC28943.1 - 5.3 6.9 20.7 0.38 10.7 15.0 1.8 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit SRF-TF PF00319.18 EGC28944.1 - 6.8e-18 63.9 0.1 1.3e-17 63.0 0.1 1.5 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Chloroplast_duf PF14476.6 EGC28945.1 - 0.028 13.4 0.0 0.05 12.6 0.0 1.4 1 0 0 1 1 1 0 Petal formation-expressed adh_short PF00106.25 EGC28946.1 - 3.6e-38 131.0 0.0 7e-38 130.1 0.0 1.4 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28946.1 - 4.7e-21 75.4 0.0 6.8e-21 74.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28946.1 - 7.2e-13 48.8 0.0 1.2e-12 48.1 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC28946.1 - 4.3e-07 29.7 0.1 1.1e-06 28.3 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC28946.1 - 5.3e-05 22.8 0.0 8.9e-05 22.0 0.0 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase DUF1776 PF08643.10 EGC28946.1 - 0.00038 19.9 0.1 0.00057 19.3 0.1 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGC28946.1 - 0.0019 17.4 0.1 0.0026 17.0 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Gag_p17 PF00540.18 EGC28946.1 - 0.044 13.8 0.1 0.066 13.2 0.1 1.3 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) NAD_binding_10 PF13460.6 EGC28946.1 - 0.088 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H-binding ABC_tran PF00005.27 EGC28947.1 - 7.4e-34 117.2 0.0 1.6e-20 74.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EGC28947.1 - 5.3e-21 74.4 2.9 5.3e-21 74.4 2.9 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.6 EGC28947.1 - 4.8e-13 49.6 0.0 0.0031 17.4 0.0 3.3 3 0 0 3 3 3 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGC28947.1 - 6.3e-08 33.4 7.0 0.014 15.9 0.1 4.1 4 0 0 4 4 4 2 AAA domain AAA_29 PF13555.6 EGC28947.1 - 1e-07 31.6 0.0 0.0038 16.9 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGC28947.1 - 1.5e-07 31.1 0.3 0.005 16.3 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGC28947.1 - 2.9e-07 30.6 5.3 0.0029 17.4 0.0 3.3 2 1 1 3 3 3 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGC28947.1 - 2.2e-06 27.7 0.8 0.0091 15.9 0.0 3.1 3 0 0 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC28947.1 - 1.4e-05 25.1 0.0 0.018 15.1 0.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGC28947.1 - 3.6e-05 24.2 0.0 0.028 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGC28947.1 - 5.4e-05 23.5 0.1 0.1 13.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase NACHT PF05729.12 EGC28947.1 - 9.3e-05 22.4 0.6 0.38 10.7 0.0 3.1 2 1 0 2 2 2 2 NACHT domain AAA_22 PF13401.6 EGC28947.1 - 0.00013 22.3 0.0 0.075 13.3 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_24 PF13479.6 EGC28947.1 - 0.00014 21.6 0.3 0.43 10.3 0.0 2.9 4 0 0 4 4 3 2 AAA domain AAA_14 PF13173.6 EGC28947.1 - 0.00061 19.8 0.0 0.78 9.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGC28947.1 - 0.00063 19.9 0.0 0.69 10.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGC28947.1 - 0.0011 19.4 0.0 0.2 12.1 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGC28947.1 - 0.0012 18.3 0.0 0.17 11.4 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_25 PF13481.6 EGC28947.1 - 0.0014 18.2 0.0 1.1 8.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGC28947.1 - 0.0038 17.2 0.1 0.94 9.5 0.1 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGC28947.1 - 0.0045 16.2 0.0 0.23 10.6 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain G-alpha PF00503.20 EGC28947.1 - 0.0051 16.0 0.1 0.29 10.2 0.1 2.5 2 1 0 2 2 2 1 G-protein alpha subunit AAA_18 PF13238.6 EGC28947.1 - 0.0052 17.3 0.0 1.5 9.4 0.0 2.9 3 0 0 3 3 2 1 AAA domain DUF2813 PF11398.8 EGC28947.1 - 0.0073 15.6 0.0 3.8 6.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2813) AAA_28 PF13521.6 EGC28947.1 - 0.01 16.1 0.0 1.8 8.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGC28947.1 - 0.012 15.7 2.5 0.48 10.5 0.0 3.3 3 1 1 4 4 4 0 Helicase HerA, central domain Roc PF08477.13 EGC28947.1 - 0.012 15.8 0.0 0.51 10.6 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EGC28947.1 - 0.014 14.7 0.0 2.7 7.2 0.0 2.4 2 0 0 2 2 2 0 Septin NTPase_1 PF03266.15 EGC28947.1 - 0.021 14.8 0.1 0.49 10.3 0.1 2.6 2 0 0 2 2 2 0 NTPase TsaE PF02367.17 EGC28947.1 - 0.025 14.6 0.3 3.9 7.5 0.0 3.0 2 1 1 3 3 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PduV-EutP PF10662.9 EGC28947.1 - 0.027 14.2 0.6 12 5.6 0.0 3.3 4 0 0 4 4 3 0 Ethanolamine utilisation - propanediol utilisation ATPase_2 PF01637.18 EGC28947.1 - 0.028 14.3 1.3 1.6 8.6 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea Rad17 PF03215.15 EGC28947.1 - 0.042 13.8 0.1 17 5.3 0.0 2.8 3 0 0 3 3 3 0 Rad17 P-loop domain DUF815 PF05673.13 EGC28947.1 - 0.044 12.9 0.1 1.5 7.9 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 EGC28947.1 - 0.056 13.0 0.0 11 5.6 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B MeaB PF03308.16 EGC28947.1 - 0.057 12.4 0.0 8.8 5.2 0.0 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_17 PF13207.6 EGC28947.1 - 0.11 12.9 0.0 16 5.9 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EGC28947.1 - 0.12 11.9 0.0 17 5.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.17 EGC28947.1 - 0.2 11.4 1.3 7.7 6.2 0.0 3.2 4 0 0 4 4 3 0 Conserved hypothetical ATP binding protein ADP_ribosyl_GH PF03747.14 EGC28948.1 - 6.7e-64 216.4 0.0 8e-64 216.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase DUF1129 PF06570.11 EGC28948.1 - 0.051 13.1 0.3 0.18 11.3 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1129) RMI1_N PF08585.12 EGC28949.1 - 2.1e-33 115.9 13.1 1.8e-17 63.9 0.0 3.4 1 1 2 3 3 3 2 RecQ mediated genome instability protein RMI1_C PF16099.5 EGC28949.1 - 0.00082 19.2 0.5 0.021 14.7 0.1 2.7 2 1 1 3 3 3 1 Recq-mediated genome instability protein 1, C-terminal OB-fold cwf18 PF08315.12 EGC28949.1 - 0.066 13.9 6.0 0.15 12.7 6.0 1.6 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor LBP_BPI_CETP_C PF02886.17 EGC28950.1 - 4.9e-11 42.5 3.1 9.5e-11 41.6 3.1 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain AMP-binding PF00501.28 EGC28951.1 - 6.4e-74 249.0 0.0 8.2e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC28951.1 - 8.2e-10 38.5 2.5 2e-09 37.2 2.5 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC28951.1 - 1.6e-09 38.6 0.0 3e-09 37.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.32 EGC28952.1 - 3.5e-07 30.8 0.1 0.32 11.9 0.3 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC28952.1 - 9.7e-05 22.6 0.0 3.8 7.9 0.0 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Reg_prop PF07494.11 EGC28952.1 - 0.088 13.1 0.2 33 5.2 0.1 3.7 3 0 0 3 3 3 0 Two component regulator propeller RP-C_C PF11800.8 EGC28952.1 - 0.39 10.8 10.4 0.64 10.1 10.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Spore_coat_CotO PF14153.6 EGC28952.1 - 0.45 10.4 22.1 0.66 9.9 22.1 1.3 1 0 0 1 1 1 0 Spore coat protein CotO Rap1_C PF11626.8 EGC28952.1 - 0.99 9.5 6.8 1.3 9.2 1.3 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Merozoite_SPAM PF07133.11 EGC28952.1 - 1.4 8.8 44.9 2.6 8.0 44.9 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) DUF4611 PF15387.6 EGC28952.1 - 4.6 7.5 23.5 1.7 8.9 16.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) UCH PF00443.29 EGC28953.1 - 2.6e-45 154.9 14.3 2.6e-45 154.9 14.3 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC28953.1 - 1.4e-26 93.9 20.1 1.4e-26 93.9 20.1 2.6 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.6 EGC28954.1 - 2.2e-08 34.3 17.3 2.2e-08 34.3 17.3 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC28954.1 - 3.9e-06 26.6 15.8 3.9e-06 26.6 15.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC28954.1 - 1.7e-05 24.6 15.0 3.3e-05 23.6 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC28954.1 - 6.4e-05 23.2 12.5 6.4e-05 23.2 12.5 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC28954.1 - 0.0002 21.1 12.3 0.00055 19.7 12.3 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC28954.1 - 0.0003 20.6 19.9 0.0003 20.6 19.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC28954.1 - 0.00095 19.3 25.0 0.00095 19.3 25.0 2.1 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_UBOX PF13445.6 EGC28954.1 - 0.0042 17.1 11.7 0.018 15.1 11.7 2.2 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGC28954.1 - 0.012 15.8 9.0 0.032 14.4 9.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC28954.1 - 0.089 12.9 9.2 0.43 10.7 9.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC28954.1 - 0.49 10.4 21.6 0.11 12.5 17.7 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGC28954.1 - 0.67 9.8 9.9 1.3 8.8 9.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC28954.1 - 1.4 9.1 17.8 0.69 10.1 14.3 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC28954.1 - 2.5 7.9 14.0 14 5.6 14.0 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain tRNA-synt_1b PF00579.25 EGC28955.1 - 2.8e-63 214.0 0.2 3.4e-63 213.7 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) dCache_2 PF08269.11 EGC28955.1 - 0.042 13.0 0.8 0.082 12.1 0.1 1.7 2 0 0 2 2 2 0 Cache domain TEBP_beta PF07404.11 EGC28956.1 - 0.55 9.5 2.6 0.71 9.2 2.6 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) RCC1 PF00415.18 EGC28958.1 - 8.8e-75 247.2 21.2 2.6e-15 56.8 0.2 8.7 9 0 0 9 9 9 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC28958.1 - 4.7e-36 121.9 38.1 2e-07 30.6 0.3 8.5 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat 7kD_DNA_binding PF02294.18 EGC28958.1 - 0.11 12.5 0.1 76 3.4 0.0 3.5 3 0 0 3 3 3 0 7kD DNA-binding domain ABC1 PF03109.16 EGC28961.1 - 1.3e-31 109.3 0.1 3.6e-31 107.8 0.1 1.9 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGC28962.1 - 6.7e-62 209.2 0.4 3.1e-61 207.0 0.4 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC28962.1 - 9.3e-28 97.2 0.6 2e-19 69.9 0.1 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.24 EGC28962.1 - 1.7e-05 25.4 0.8 4.5e-05 24.1 0.8 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain Haspin_kinase PF12330.8 EGC28962.1 - 0.00022 20.3 0.3 0.00034 19.7 0.3 1.3 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGC28962.1 - 0.0017 18.3 0.1 0.062 13.2 0.1 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC28962.1 - 0.0085 15.2 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGC28962.1 - 0.014 14.7 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 Kinase-like SANT_DAMP1_like PF16282.5 EGC28963.1 - 6.9e-28 96.7 7.8 8.3e-28 96.4 6.0 2.2 2 0 0 2 2 2 1 SANT/Myb-like domain of DAMP1 Myb_DNA-binding PF00249.31 EGC28963.1 - 0.00014 22.0 0.0 0.00031 20.9 0.0 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC28963.1 - 0.0018 18.5 0.3 0.012 15.8 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Olduvai PF06758.13 EGC28963.1 - 0.063 13.5 8.4 0.36 11.1 8.4 2.4 1 0 0 1 1 1 0 Olduvai domain LysM PF01476.20 EGC28965.1 - 0.0037 17.3 0.5 0.0037 17.3 0.5 2.8 2 1 0 2 2 2 1 LysM domain TNF PF00229.18 EGC28966.1 - 0.047 13.6 0.3 0.063 13.2 0.3 1.2 1 0 0 1 1 1 0 TNF(Tumour Necrosis Factor) family Exonuc_VII_L PF02601.15 EGC28966.1 - 0.13 11.8 1.2 0.15 11.6 1.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 EGC28966.1 - 0.17 11.4 12.2 1.3 8.5 0.9 2.1 1 1 1 2 2 2 0 Centromere-associated protein K FapA PF03961.13 EGC28966.1 - 2.3 6.7 8.9 2.7 6.5 8.9 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A YabA PF06156.13 EGC28966.1 - 3 8.5 7.5 8.1 7.1 7.5 1.7 1 1 0 1 1 1 0 Initiation control protein YabA adh_short PF00106.25 EGC28967.1 - 1.5e-41 142.1 0.0 1.8e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28967.1 - 5.8e-33 114.4 0.0 7.7e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28967.1 - 2.8e-07 30.6 0.0 4.3e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC28967.1 - 1.9e-05 24.2 0.1 2.8e-05 23.6 0.1 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) UNC-50 PF05216.13 EGC28968.1 - 1.4e-77 260.2 30.3 1.6e-77 260.1 30.3 1.0 1 0 0 1 1 1 1 UNC-50 family GCV_T PF01571.21 EGC28969.1 - 1.6e-88 296.4 0.0 1.9e-88 296.1 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.11 EGC28969.1 - 2.5e-17 62.6 0.0 4.3e-17 61.8 0.0 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.12 EGC28969.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Myosin_head PF00063.21 EGC28970.1 - 1.3e-205 684.6 23.1 1.3e-205 684.6 23.1 1.8 2 0 0 2 2 1 1 Myosin head (motor domain) RhoGEF PF00621.20 EGC28970.1 - 8.2e-53 179.3 1.7 8.2e-53 179.3 1.7 5.5 5 1 0 5 5 4 1 RhoGEF domain PH PF00169.29 EGC28970.1 - 1.2e-06 29.0 0.5 1.2e-06 29.0 0.5 2.6 2 0 0 2 2 1 1 PH domain Myosin_N PF02736.19 EGC28970.1 - 8.5e-05 22.3 0.0 0.00018 21.3 0.0 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain CDC45 PF02724.14 EGC28970.1 - 0.0041 15.5 23.7 0.0067 14.8 23.7 1.3 1 0 0 1 1 1 1 CDC45-like protein GBP_C PF02841.14 EGC28970.1 - 0.01 15.3 32.8 0.023 14.1 32.8 1.6 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain AAA_22 PF13401.6 EGC28970.1 - 0.032 14.5 0.7 0.19 12.0 0.0 2.7 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.6 EGC28970.1 - 0.04 14.3 0.8 0.17 12.3 0.0 2.4 3 0 0 3 3 3 0 AAA ATPase domain Borrelia_P83 PF05262.11 EGC28970.1 - 0.048 12.2 32.3 0.089 11.3 32.3 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein ABC_tran PF00005.27 EGC28970.1 - 0.063 13.8 0.1 0.063 13.8 0.1 3.6 3 1 0 3 3 2 0 ABC transporter GAGA_bind PF06217.12 EGC28970.1 - 2.7 8.2 18.3 10 6.3 18.3 2.0 1 0 0 1 1 1 0 GAGA binding protein-like family ALMT PF11744.8 EGC28970.1 - 3.5 6.4 24.3 12 4.6 24.3 1.9 1 0 0 1 1 1 0 Aluminium activated malate transporter Vfa1 PF08432.10 EGC28970.1 - 5.2 7.4 35.5 16 5.8 35.5 1.9 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DIM1 PF02966.16 EGC28971.1 - 6.3e-65 216.9 0.2 7.1e-65 216.8 0.2 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.20 EGC28971.1 - 0.00024 21.0 0.1 0.00035 20.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin DUF3192 PF11399.8 EGC28971.1 - 0.011 15.7 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) Thioredoxin_8 PF13905.6 EGC28971.1 - 0.023 15.0 0.1 0.032 14.6 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like Strep_SA_rep PF06696.11 EGC28972.1 - 0.2 11.7 2.0 2.4 8.3 0.5 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Glyco_hydro_38N PF01074.22 EGC28973.1 - 2.3e-73 247.1 1.8 2.3e-73 247.1 1.8 1.8 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC28973.1 - 2.5e-18 66.0 0.1 2.5e-17 62.8 0.1 2.6 2 0 0 2 2 2 1 Alpha mannosidase middle domain TMEM154 PF15102.6 EGC28973.1 - 0.0037 17.2 0.2 0.01 15.7 0.2 1.7 1 0 0 1 1 1 1 TMEM154 protein family Glyco_hydro38C2 PF17677.1 EGC28973.1 - 0.043 13.9 0.1 0.12 12.5 0.1 1.9 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain DUF4064 PF13273.6 EGC28973.1 - 0.68 10.2 4.1 2.2 8.6 4.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) OsmC PF02566.19 EGC28974.1 - 1.1e-21 77.2 0.1 1.5e-21 76.7 0.1 1.2 1 0 0 1 1 1 1 OsmC-like protein UAA PF08449.11 EGC28974.1 - 0.042 13.1 0.0 0.051 12.8 0.0 1.1 1 0 0 1 1 1 0 UAA transporter family HPS3_N PF14761.6 EGC28975.1 - 0.0031 17.1 7.4 0.025 14.1 0.2 3.7 4 0 0 4 4 4 2 Hermansky-Pudlak syndrome 3 Synaptobrevin PF00957.21 EGC28975.1 - 0.026 14.3 0.2 0.026 14.3 0.2 1.9 2 0 0 2 2 2 0 Synaptobrevin WD40 PF00400.32 EGC28975.1 - 0.079 13.9 3.4 53 4.9 0.1 4.4 4 0 0 4 4 4 0 WD domain, G-beta repeat UBN_AB PF14075.6 EGC28976.1 - 0.011 15.4 0.4 0.02 14.6 0.4 1.4 1 0 0 1 1 1 0 Ubinuclein conserved middle domain DUF713 PF05218.14 EGC28976.1 - 0.16 11.7 4.1 0.21 11.3 0.9 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF713) Bact_lectin PF18483.1 EGC28977.1 - 1.6e-24 87.1 3.8 1.6e-24 87.1 3.8 2.0 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 EGC28977.1 - 1.7e-18 67.1 1.8 1.7e-18 67.1 1.8 1.5 2 0 0 2 2 2 1 Legume lectin domain Laminin_G_1 PF00054.23 EGC28977.1 - 0.0065 16.7 0.1 0.034 14.3 0.0 2.0 2 0 0 2 2 2 1 Laminin G domain HALZ PF02183.18 EGC28977.1 - 0.043 14.0 3.1 0.094 13.0 3.1 1.6 1 0 0 1 1 1 0 Homeobox associated leucine zipper ZapB PF06005.12 EGC28977.1 - 0.083 13.3 1.9 0.2 12.1 1.9 1.6 1 0 0 1 1 1 0 Cell division protein ZapB EGF_CA PF07645.15 EGC28978.1 - 3.2e-05 24.0 6.1 3.2e-05 24.0 6.1 5.1 3 1 1 4 4 4 1 Calcium-binding EGF domain cEGF PF12662.7 EGC28978.1 - 0.00029 20.7 3.5 0.00029 20.7 3.5 4.8 4 0 0 4 4 4 2 Complement Clr-like EGF-like FXa_inhibition PF14670.6 EGC28978.1 - 0.00035 20.8 5.4 0.00035 20.8 5.4 5.0 2 2 2 4 4 4 1 Coagulation Factor Xa inhibitory site Podoplanin PF05808.11 EGC28978.1 - 0.018 15.2 0.1 0.03 14.4 0.1 1.4 1 0 0 1 1 1 0 Podoplanin MtrF PF09472.10 EGC28978.1 - 0.074 12.5 0.2 0.19 11.1 0.2 1.7 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) EGF_2 PF07974.13 EGC28978.1 - 8.5 6.8 59.2 0.054 13.9 15.3 4.9 4 0 0 4 4 4 0 EGF-like domain adh_short PF00106.25 EGC28979.1 - 6.2e-33 113.9 0.0 7.7e-33 113.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC28979.1 - 8e-14 51.8 0.0 1e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC28979.1 - 0.00014 21.8 0.0 0.0002 21.4 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC28979.1 - 0.0043 16.2 0.0 0.0058 15.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FNIP PF05725.12 EGC28980.1 - 1.2e-92 303.9 57.5 5e-16 58.6 1.6 10.4 10 0 0 10 10 10 9 FNIP Repeat Androgen_recep PF02166.16 EGC28980.1 - 0.0047 15.8 12.6 0.0069 15.3 12.6 1.2 1 0 0 1 1 1 1 Androgen receptor SUIM_assoc PF16619.5 EGC28980.1 - 9.3 6.4 26.2 4e+02 1.2 26.2 2.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Ufd2P_core PF10408.9 EGC28981.1 - 1.3e-176 588.9 17.2 2.2e-176 588.2 17.2 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.15 EGC28981.1 - 4.1e-30 103.8 2.8 7.2e-30 103.0 1.4 2.3 2 0 0 2 2 2 1 U-box domain Ribosomal_S4Pg PF11993.8 EGC28981.1 - 0.023 14.8 3.5 0.066 13.3 3.5 1.7 1 0 0 1 1 1 0 Ribosomal S4P (gammaproteobacterial) SUIM_assoc PF16619.5 EGC28981.1 - 0.77 9.9 5.8 2.2 8.4 5.8 1.8 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Roughex PF06020.11 EGC28981.1 - 4.3 6.3 7.4 7.3 5.6 6.6 1.7 2 0 0 2 2 2 0 Drosophila roughex protein ATF7IP_BD PF16788.5 EGC28981.1 - 6.8 6.7 12.8 16 5.5 12.8 1.6 1 0 0 1 1 1 0 ATF-interacting protein binding domain Ras PF00071.22 EGC28982.1 - 2.6e-28 98.7 0.4 5.4e-28 97.6 0.4 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC28982.1 - 1.8e-11 44.3 0.3 3e-10 40.4 0.0 2.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGC28982.1 - 6.7e-06 25.8 0.3 0.00091 18.8 0.2 2.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.21 EGC28982.1 - 3.3e-05 23.4 0.1 0.0003 20.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC28982.1 - 0.0015 18.6 0.1 0.0046 17.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC28982.1 - 0.0097 15.4 0.2 0.099 12.2 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Isy1 PF06246.12 EGC28982.1 - 0.025 14.1 1.1 0.025 14.1 1.1 1.8 1 1 1 2 2 2 0 Isy1-like splicing family TIG PF01833.24 EGC28983.1 - 9.4e-06 25.6 18.0 0.014 15.5 0.3 3.1 2 1 1 3 3 3 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC28983.1 - 0.11 12.6 0.2 0.11 12.6 0.2 3.6 3 1 0 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC28983.1 - 4.6 7.7 38.9 0.21 12.0 13.2 4.2 4 0 0 4 4 4 0 EGF-like domain EF-hand_8 PF13833.6 EGC28984.1 - 0.078 12.8 0.1 0.12 12.2 0.1 1.3 1 0 0 1 1 1 0 EF-hand domain pair DUF4576 PF15144.6 EGC28984.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4576) Oxidored_FMN PF00724.20 EGC28985.1 - 4.9e-06 26.0 0.0 4.9e-06 26.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family P16-Arc PF04699.14 EGC28986.1 - 3.1e-34 118.6 0.1 3.7e-34 118.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) Nop10p PF04135.12 EGC28987.1 - 3.1e-19 68.8 0.4 3.5e-19 68.6 0.4 1.1 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ins_P5_2-kin PF06090.12 EGC28988.1 - 2.3e-97 326.4 0.5 2.7e-97 326.2 0.5 1.0 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Kinesin PF00225.23 EGC28989.1 - 7.1e-103 344.0 0.2 7.1e-103 344.0 0.2 3.5 4 2 1 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGC28989.1 - 2.3e-24 86.0 0.1 2.3e-24 86.0 0.1 4.0 3 1 0 4 4 4 1 Microtubule binding DUF3015 PF11220.8 EGC28989.1 - 0.0073 16.2 1.1 0.0073 16.2 1.1 4.8 6 0 0 6 6 6 2 Protein of unknown function (DUF3015) AphA_like PF14557.6 EGC28989.1 - 0.035 13.8 0.0 0.088 12.5 0.0 1.6 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator AAA_22 PF13401.6 EGC28989.1 - 0.27 11.5 10.1 0.39 11.0 0.0 4.1 4 1 0 4 4 4 0 AAA domain FUSC PF04632.12 EGC28989.1 - 0.86 8.1 1.7 29 3.0 0.1 2.1 1 1 1 2 2 2 0 Fusaric acid resistance protein family SICA_C PF12879.7 EGC28989.1 - 1.1 9.3 9.5 0.026 14.6 1.1 2.6 3 0 0 3 3 3 0 SICA C-terminal inner membrane domain Prefoldin_3 PF13758.6 EGC28989.1 - 6.1 7.0 13.7 0.25 11.4 2.3 4.1 2 1 1 3 3 3 0 Prefoldin subunit Il2rg PF15874.5 EGC28989.1 - 7.7 6.8 8.3 0.46 10.8 1.3 2.7 3 0 0 3 3 3 0 Putative Interleukin 2 receptor, gamma chain CBS PF00571.28 EGC28990.1 - 3.3e-13 49.9 1.0 0.0029 18.0 0.2 4.7 3 1 1 4 4 4 4 CBS domain Baculo_LEF-10 PF07206.11 EGC28990.1 - 0.41 10.8 4.7 18 5.6 0.3 3.5 3 0 0 3 3 3 0 Baculovirus late expression factor 10 (LEF-10) Ribosomal_L29 PF00831.23 EGC28991.1 - 6.1e-17 61.3 5.0 8e-17 61.0 0.8 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein ERM PF00769.19 EGC28991.1 - 0.014 15.2 1.1 0.014 15.2 1.1 1.7 2 0 0 2 2 2 0 Ezrin/radixin/moesin family LURAP PF14854.6 EGC28991.1 - 0.1 12.6 0.4 0.17 11.8 0.2 1.4 1 1 0 1 1 1 0 Leucine rich adaptor protein Snapin_Pallidin PF14712.6 EGC28991.1 - 0.11 12.9 3.1 0.12 12.8 0.7 1.9 1 1 1 2 2 2 0 Snapin/Pallidin SIR2 PF02146.17 EGC28992.1 - 2.1e-58 197.2 0.0 3.8e-58 196.3 0.0 1.4 1 0 0 1 1 1 1 Sir2 family TPP_enzyme_M PF00205.22 EGC28992.1 - 0.00016 21.4 0.0 0.36 10.5 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain FAS_N PF17828.1 EGC28992.1 - 0.0032 17.5 0.3 0.0065 16.5 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain in fatty acid synthase subunit beta HNF-1_N PF04814.13 EGC28992.1 - 0.005 17.5 5.4 0.01 16.4 5.4 1.5 1 0 0 1 1 1 1 Hepatocyte nuclear factor 1 (HNF-1), N terminus DUF1272 PF06906.11 EGC28992.1 - 0.012 15.7 0.7 0.025 14.7 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Myc_N PF01056.18 EGC28992.1 - 0.048 13.6 4.6 0.071 13.0 4.6 1.2 1 0 0 1 1 1 0 Myc amino-terminal region Mucin PF01456.17 EGC28992.1 - 1.5 8.8 23.6 2.4 8.1 23.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Aminotran_5 PF00266.19 EGC28993.1 - 1e-37 130.0 0.0 1.5e-37 129.4 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V PALP PF00291.25 EGC28993.1 - 0.0011 18.4 0.0 0.0022 17.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme DegT_DnrJ_EryC1 PF01041.17 EGC28993.1 - 0.01 15.1 0.0 0.046 13.0 0.0 1.8 2 0 0 2 2 2 0 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGC28993.1 - 0.037 12.6 0.0 0.053 12.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 EGC28993.1 - 0.037 12.7 0.3 0.26 10.0 0.0 2.2 3 0 0 3 3 3 0 Pyridoxal-dependent decarboxylase conserved domain zinc_ribbon_10 PF10058.9 EGC28994.1 - 1.5e-16 59.8 0.1 3.2e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein LMBR1 PF04791.16 EGC28994.1 - 0.00037 19.5 3.7 0.00037 19.5 3.7 3.1 2 1 0 2 2 2 1 LMBR1-like membrane protein TMF_DNA_bd PF12329.8 EGC28994.1 - 0.0018 18.3 12.3 0.0018 18.3 12.3 6.4 4 2 2 6 6 6 1 TATA element modulatory factor 1 DNA binding Gelsolin PF00626.22 EGC28995.1 - 7.1e-49 163.6 0.0 4.2e-16 58.6 0.0 3.1 3 0 0 3 3 3 3 Gelsolin repeat UDPGP PF01704.18 EGC28996.1 - 9.9e-154 511.9 4.3 9.9e-154 511.9 4.3 1.4 2 0 0 2 2 2 1 UTP--glucose-1-phosphate uridylyltransferase FtsJ PF01728.19 EGC28997.1 - 6.5e-08 32.9 0.0 1.3e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Pkinase_Tyr PF07714.17 EGC28998.1 - 2.2e-70 236.9 0.1 4.7e-70 235.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC28998.1 - 6.5e-67 225.7 0.0 6.5e-67 225.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Kdo PF06293.14 EGC28998.1 - 0.02 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Gti1_Pac2 PF09729.9 EGC28998.1 - 0.45 10.6 31.7 0.94 9.5 16.5 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family Presenilin PF01080.17 EGC28998.1 - 9.1 4.9 32.8 4.4 6.0 8.2 2.2 2 0 0 2 2 2 0 Presenilin Myotub-related PF06602.14 EGC28999.1 - 1.6e-75 254.3 0.7 1.6e-75 254.3 0.7 2.6 2 0 0 2 2 1 1 Myotubularin-like phosphatase domain COR PF16095.5 EGC28999.1 - 5.8e-57 192.6 0.2 1.6e-56 191.2 0.2 1.8 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase_Tyr PF07714.17 EGC28999.1 - 2.4e-48 164.7 0.0 4.2e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC28999.1 - 3.6e-38 131.4 0.0 8.6e-38 130.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Roc PF08477.13 EGC28999.1 - 1.5e-25 89.7 0.5 6e-25 87.8 0.5 2.1 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 EGC28999.1 - 3.8e-23 81.0 68.4 3.3e-06 26.8 8.8 7.3 4 2 3 7 7 6 6 Leucine rich repeat Ras PF00071.22 EGC28999.1 - 6.1e-13 48.7 0.7 1.5e-12 47.4 0.7 1.6 1 0 0 1 1 1 1 Ras family LRR_4 PF12799.7 EGC28999.1 - 3e-08 33.8 100.5 0.00053 20.3 5.5 11.1 4 2 8 13 13 12 9 Leucine Rich repeats (2 copies) Arf PF00025.21 EGC28999.1 - 4.7e-06 26.2 3.9 2.2e-05 24.0 3.9 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family WD40 PF00400.32 EGC28999.1 - 7.2e-05 23.5 11.9 1 10.3 0.5 5.7 5 0 0 5 5 4 1 WD domain, G-beta repeat AAA_22 PF13401.6 EGC28999.1 - 0.00028 21.2 0.1 1.7 9.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC28999.1 - 0.00076 19.5 0.1 0.0032 17.5 0.0 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC28999.1 - 0.0048 16.4 0.1 0.45 10.0 0.1 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B RA PF00788.23 EGC28999.1 - 0.022 15.4 0.0 0.086 13.5 0.0 2.0 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain TniB PF05621.11 EGC28999.1 - 0.035 13.5 0.0 0.08 12.3 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_24 PF13479.6 EGC28999.1 - 0.1 12.3 0.1 0.22 11.2 0.1 1.6 1 0 0 1 1 1 0 AAA domain Ank_2 PF12796.7 EGC29000.1 - 1.6e-08 35.0 0.3 0.00048 20.7 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC29000.1 - 1.8e-06 27.8 0.1 0.097 13.3 0.0 4.8 4 0 0 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGC29000.1 - 3.3e-06 27.3 0.0 3.3e-06 27.3 0.0 4.5 5 0 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC29000.1 - 4.4e-06 26.9 0.4 0.043 14.3 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Ank_4 PF13637.6 EGC29000.1 - 3.6e-05 24.2 0.1 0.064 13.9 0.0 3.5 1 1 3 4 4 4 3 Ankyrin repeats (many copies) EVE PF01878.18 EGC29000.1 - 0.036 14.1 0.0 0.1 12.6 0.0 1.7 1 0 0 1 1 1 0 EVE domain PHF5 PF03660.14 EGC29002.1 - 5.4e-51 171.1 12.2 6.1e-51 171.0 12.2 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.13 EGC29002.1 - 0.0081 14.1 6.7 0.0081 14.1 6.7 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 DZR PF12773.7 EGC29002.1 - 1.7 8.7 16.7 0.39 10.8 3.0 3.0 1 1 1 2 2 2 0 Double zinc ribbon C1_2 PF03107.16 EGC29002.1 - 7 7.1 19.7 1.8 9.0 4.1 2.6 1 1 1 2 2 2 0 C1 domain Ribosomal_L27A PF00828.19 EGC29003.1 - 9.6e-32 110.4 1.4 1.8e-31 109.5 1.4 1.4 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A N_BRCA1_IG PF16158.5 EGC29004.1 - 9.8e-19 68.0 0.0 2.6e-18 66.6 0.0 1.8 1 0 0 1 1 1 1 Ig-like domain from next to BRCA1 gene Hexapep PF00132.24 EGC29005.1 - 2e-10 39.9 6.8 5.6e-05 22.7 0.4 3.5 1 1 2 3 3 3 3 Bacterial transferase hexapeptide (six repeats) DUF4954 PF16314.5 EGC29005.1 - 0.0006 18.1 0.6 0.00094 17.4 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGC29005.1 - 0.0048 15.9 0.8 0.007 15.4 0.8 1.4 1 0 0 1 1 1 1 L-fucokinase NTP_transf_3 PF12804.7 EGC29005.1 - 0.019 15.3 0.0 0.025 15.0 0.0 1.2 1 0 0 1 1 1 0 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGC29005.1 - 1.4 8.8 8.3 4.8 7.0 2.1 3.3 2 1 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase Cyt-b5 PF00173.28 EGC29006.1 - 4.2e-20 71.7 0.2 4.4e-20 71.6 0.2 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUDIX PF00293.28 EGC29007.1 - 1.1e-21 77.2 0.0 1.3e-21 77.0 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGC29007.1 - 0.00084 19.3 0.0 0.0019 18.2 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain MIP PF00230.20 EGC29008.1 - 1.2e-26 93.8 9.7 1.6e-26 93.4 9.7 1.2 1 0 0 1 1 1 1 Major intrinsic protein Alpha_kinase PF02816.18 EGC29009.1 - 5.3e-56 189.7 0.3 4.9e-55 186.5 0.1 2.2 2 0 0 2 2 2 1 Alpha-kinase family WD40 PF00400.32 EGC29009.1 - 6.8e-19 67.9 12.8 0.00012 22.8 0.1 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.8 EGC29009.1 - 1.1e-08 34.2 8.1 0.00014 20.7 0.5 3.5 2 2 1 3 3 3 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGC29009.1 - 2.9e-08 33.4 7.2 2.4e-05 23.8 2.1 2.4 2 1 1 3 3 3 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGC29009.1 - 0.00022 21.5 2.7 1 9.7 0.1 4.3 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGC29009.1 - 0.061 13.8 0.0 1.2e+02 3.4 0.0 3.9 4 0 0 4 4 4 0 PQQ-like domain DUF1513 PF07433.11 EGC29009.1 - 0.18 10.9 0.0 3.7 6.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Hamartin PF04388.12 EGC29009.1 - 6.6 5.3 8.6 9.1 4.8 8.6 1.1 1 0 0 1 1 1 0 Hamartin protein EF-hand_4 PF12763.7 EGC29011.1 - 1.5e-18 66.6 0.0 1.5e-18 66.6 0.0 2.6 2 2 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.32 EGC29011.1 - 0.012 15.1 0.1 0.027 14.0 0.1 1.6 1 0 0 1 1 1 0 EF hand DUF3069 PF11269.8 EGC29011.1 - 0.081 13.2 4.4 0.2 11.9 1.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3069) CBFD_NFYB_HMF PF00808.23 EGC29012.1 - 5.6e-20 71.4 0.2 9.9e-20 70.6 0.2 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC29012.1 - 0.00064 20.1 2.0 0.0012 19.2 0.0 2.1 2 1 0 2 2 2 1 Core histone H2A/H2B/H3/H4 Phage_Mu_Gam PF07352.12 EGC29012.1 - 0.21 11.5 7.8 0.76 9.7 7.8 1.9 1 1 0 1 1 1 0 Bacteriophage Mu Gam like protein Dimer_Tnp_hAT PF05699.14 EGC29014.1 - 4.2e-13 48.9 0.3 9.6e-13 47.7 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MCM3AP_GANP PF16769.5 EGC29014.1 - 0.0031 15.9 2.0 0.0037 15.6 2.0 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP RICTOR_N PF14664.6 EGC29014.1 - 0.02 13.9 0.5 0.21 10.5 0.6 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term MTBP_C PF14920.6 EGC29014.1 - 0.029 14.1 0.5 0.038 13.7 0.5 1.1 1 0 0 1 1 1 0 MDM2-binding CLN3 PF02487.17 EGC29014.1 - 0.35 9.9 2.4 0.46 9.5 2.4 1.1 1 0 0 1 1 1 0 CLN3 protein DUF4681 PF15732.5 EGC29019.1 - 0.087 13.1 0.0 0.11 12.7 0.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4681) zf-RING_2 PF13639.6 EGC29020.1 - 1.3e-10 41.4 9.2 2.2e-10 40.7 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29020.1 - 2.6e-10 40.0 6.1 4.2e-10 39.3 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29020.1 - 1.3e-09 37.7 8.5 2.2e-09 37.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29020.1 - 7.9e-08 32.0 9.2 1.5e-07 31.1 9.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29020.1 - 2.7e-06 27.3 3.8 5.9e-06 26.2 3.8 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC29020.1 - 1.9e-05 24.9 6.2 6e-05 23.3 6.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC29020.1 - 3.8e-05 23.6 6.7 7.5e-05 22.6 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC29020.1 - 6.4e-05 22.7 5.0 0.00015 21.6 4.9 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC29020.1 - 0.0002 21.0 5.7 0.00045 19.9 5.7 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC29020.1 - 0.00048 20.2 8.5 0.0011 19.0 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC29020.1 - 0.0033 17.2 10.0 0.0066 16.2 10.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC29020.1 - 0.0069 16.0 5.1 0.011 15.3 5.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_9 PF14369.6 EGC29020.1 - 0.023 14.9 6.2 0.023 14.9 6.2 2.1 2 0 0 2 2 2 0 zinc-ribbon zf-RING_6 PF14835.6 EGC29020.1 - 0.045 13.6 2.4 0.085 12.7 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGC29020.1 - 0.2 11.7 5.2 0.55 10.3 5.2 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger YjbH PF06082.11 EGC29020.1 - 0.99 8.1 19.2 1.1 7.9 19.2 1.0 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH RNA_ligase PF09414.10 EGC29022.1 - 6e-22 78.7 0.1 8.8e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 RNA ligase MutL_C PF08676.11 EGC29022.1 - 0.028 14.2 0.0 2.6 7.8 0.0 2.3 2 0 0 2 2 2 0 MutL C terminal dimerisation domain Ras PF00071.22 EGC29023.1 - 2.6e-08 33.6 0.0 4.5e-08 32.9 0.0 1.4 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC29023.1 - 0.00036 20.7 0.0 0.0045 17.2 0.0 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EGC29023.1 - 0.0059 16.6 0.8 0.013 15.5 0.1 1.8 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGC29023.1 - 0.011 15.8 0.0 0.054 13.6 0.0 2.2 1 1 0 1 1 1 0 50S ribosome-binding GTPase RecG_wedge PF17191.4 EGC29023.1 - 0.034 13.8 0.4 0.9 9.1 0.1 2.4 1 1 1 2 2 2 0 RecG wedge domain Mob1_phocein PF03637.17 EGC29024.1 - 2.6e-32 112.2 5.6 3.7e-32 111.7 5.6 1.2 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_S14 PF00253.21 EGC29025.1 - 2.2e-14 52.9 3.0 2.4e-14 52.8 3.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e DUF1451 PF07295.11 EGC29025.1 - 0.1 12.6 0.6 0.13 12.3 0.6 1.1 1 0 0 1 1 1 0 Zinc-ribbon containing domain DUF1289 PF06945.13 EGC29025.1 - 0.28 11.0 4.4 0.33 10.8 0.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1289) Pkinase_Tyr PF07714.17 EGC29026.1 - 4.1e-48 163.9 0.0 7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC29026.1 - 2.5e-43 148.3 0.0 4.8e-43 147.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain C2 PF00168.30 EGC29026.1 - 3.5e-21 75.4 0.0 1.1e-20 73.8 0.0 1.9 2 0 0 2 2 1 1 C2 domain Ank_2 PF12796.7 EGC29026.1 - 2.1e-16 60.2 0.0 1.2e-10 41.8 0.0 2.7 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC29026.1 - 8.9e-12 44.1 0.1 0.0053 17.2 0.0 5.0 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGC29026.1 - 3e-11 43.6 0.0 0.0025 18.3 0.0 4.3 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC29026.1 - 1.5e-09 37.9 6.0 7e-05 23.0 0.0 4.9 3 1 2 5 5 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC29026.1 - 1.2e-08 35.0 0.0 0.013 15.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat SAM_1 PF00536.30 EGC29026.1 - 1.6e-05 25.3 0.4 3.8e-05 24.0 0.4 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC29026.1 - 0.0077 16.3 0.2 0.024 14.7 0.2 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.23 EGC29026.1 - 0.28 11.1 0.1 1 9.2 0.2 1.7 1 1 0 2 2 2 0 Phosphotransferase enzyme family Mucin PF01456.17 EGC29026.1 - 1.2 9.1 32.0 0.022 14.7 23.9 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein SOG2 PF10428.9 EGC29026.1 - 6.4 5.8 41.6 0.71 9.0 19.7 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein Membralin PF09746.9 EGC29026.1 - 7.4 5.5 7.7 14 4.6 7.7 1.4 1 0 0 1 1 1 0 Tumour-associated protein NDT80_PhoG PF05224.12 EGC29027.1 - 4.5e-14 53.1 0.4 4.5e-14 53.1 0.4 6.2 4 3 1 5 5 5 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 EGC29027.1 - 1.4e-11 44.6 0.2 3.3e-11 43.3 0.2 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase DUF2975 PF11188.8 EGC29027.1 - 0.1 12.5 3.9 0.19 11.6 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) VIT1 PF01988.19 EGC29027.1 - 0.61 9.9 1.5 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 VIT family zf-RING_9 PF13901.6 EGC29028.1 - 9e-60 202.2 9.6 9e-60 202.2 9.6 2.7 4 0 0 4 4 4 1 Putative zinc-RING and/or ribbon RUN PF02759.19 EGC29028.1 - 7.8e-12 45.3 5.0 1.1e-11 44.8 1.3 3.1 2 1 0 2 2 2 1 RUN domain VCX_VCY PF15231.6 EGC29028.1 - 0.35 11.6 2.0 1 10.0 2.0 1.8 1 0 0 1 1 1 0 Variable charge X/Y family Prok-RING_1 PF14446.6 EGC29028.1 - 6.3 6.8 11.5 0.77 9.7 6.4 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 dUTPase PF00692.19 EGC29029.1 - 6.4e-09 35.6 0.0 3.5e-08 33.2 0.0 1.8 1 1 1 2 2 2 1 dUTPase DCD PF06559.11 EGC29029.1 - 2.4e-06 26.6 0.0 0.015 14.1 0.0 2.1 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) SprA-related PF12118.8 EGC29030.1 - 0.096 11.8 25.0 0.0083 15.3 20.3 1.6 1 1 0 1 1 1 0 SprA-related family DUF4407 PF14362.6 EGC29030.1 - 1.9 7.8 18.4 0.044 13.1 12.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) FapA PF03961.13 EGC29030.1 - 6.5 5.2 18.8 10 4.6 18.8 1.3 1 0 0 1 1 1 0 Flagellar Assembly Protein A CtaG_Cox11 PF04442.14 EGC29032.1 - 2.3e-57 193.3 0.4 3e-57 192.9 0.4 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RhodobacterPufX PF11511.8 EGC29032.1 - 0.0046 16.5 0.0 0.0074 15.9 0.0 1.3 1 0 0 1 1 1 1 Intrinsic membrane protein PufX ESSS PF10183.9 EGC29032.1 - 0.072 13.3 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Ank_2 PF12796.7 EGC29033.1 - 2.4e-05 24.8 0.9 0.22 12.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) DUF2833 PF11090.8 EGC29033.1 - 4.7 7.7 9.1 15 6.1 0.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2833) Syntaxin PF00804.25 EGC29034.1 - 7.1e-43 146.6 14.3 1.4e-42 145.7 14.3 1.5 1 0 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGC29034.1 - 7.8e-13 48.2 3.2 2.3e-12 46.7 3.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin_2 PF14523.6 EGC29034.1 - 0.0015 18.9 8.4 0.0015 18.9 8.4 2.7 2 1 0 2 2 2 1 Syntaxin-like protein DUF4369 PF14289.6 EGC29034.1 - 0.062 13.8 1.8 0.15 12.6 1.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4369) VitD-bind_III PF09164.10 EGC29034.1 - 0.083 12.9 2.3 0.44 10.6 0.3 2.6 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF2116 PF09889.9 EGC29034.1 - 0.43 10.6 1.4 1 9.4 1.4 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) V-SNARE PF05008.15 EGC29034.1 - 2.5 8.5 15.5 24 5.4 1.4 4.2 2 2 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus PRKG1_interact PF15898.5 EGC29034.1 - 2.9 8.8 15.6 0.25 12.3 7.4 2.8 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain PIEZO PF15917.5 EGC29034.1 - 3.8 6.9 11.9 8.5 5.8 11.9 1.5 1 0 0 1 1 1 0 Piezo AI-2E_transport PF01594.16 EGC29034.1 - 5.4 6.1 11.5 3.5 6.7 0.5 2.7 3 0 0 3 3 3 0 AI-2E family transporter 6PGD PF00393.19 EGC29035.1 - 2.8e-128 427.3 0.0 3.4e-128 427.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGC29035.1 - 3.4e-52 176.8 0.0 4.9e-52 176.3 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.20 EGC29035.1 - 0.004 17.2 0.1 0.008 16.3 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.6 EGC29035.1 - 0.084 13.1 0.0 0.21 11.8 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase PGK PF00162.19 EGC29035.1 - 0.14 11.1 0.0 0.21 10.5 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase Hydrolase_6 PF13344.6 EGC29036.1 - 0.092 12.9 0.5 0.43 10.7 0.0 2.2 2 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase 5_3_exonuc PF01367.20 EGC29036.1 - 0.15 12.7 2.2 0.41 11.3 2.2 1.8 1 1 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold Imm3 PF14425.6 EGC29036.1 - 0.87 9.6 8.9 2.4 8.2 8.9 1.8 1 1 0 1 1 1 0 Immunity protein Imm3 ABC_tran_CTD PF16326.5 EGC29036.1 - 2.7 8.3 8.8 0.28 11.4 3.5 2.0 2 0 0 2 2 2 0 ABC transporter C-terminal domain Apc13p PF05839.11 EGC29037.1 - 5.3e-06 26.5 2.4 0.00024 21.2 2.4 2.0 1 1 0 1 1 1 1 Apc13p protein Dynamin_M PF01031.20 EGC29038.1 - 5.9e-101 337.4 0.2 5.9e-101 337.4 0.2 2.1 3 0 0 3 3 3 1 Dynamin central region Dynamin_N PF00350.23 EGC29038.1 - 1.4e-59 200.9 0.0 1.4e-59 200.9 0.0 2.6 3 1 0 3 3 3 1 Dynamin family GED PF02212.18 EGC29038.1 - 3.1e-33 113.8 3.5 3.1e-33 113.8 3.5 2.1 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGC29038.1 - 2.1e-05 24.6 0.2 0.00013 22.0 0.2 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC29038.1 - 0.015 14.8 2.0 1.3 8.5 0.1 3.1 3 0 0 3 3 3 0 Ferrous iron transport protein B Roc PF08477.13 EGC29038.1 - 0.082 13.1 0.0 2.3 8.4 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase AAA_16 PF13191.6 EGC29038.1 - 0.092 13.1 0.0 1.4 9.3 0.0 2.8 3 1 0 3 3 3 0 AAA ATPase domain CorA PF01544.18 EGC29039.1 - 1e-65 222.0 2.7 1.4e-65 221.6 2.7 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein MINDY_DUB PF04424.13 EGC29039.1 - 0.0067 16.4 0.6 1.6 8.8 0.1 2.6 2 0 0 2 2 2 2 MINDY deubiquitinase MHCassoc_trimer PF08831.10 EGC29039.1 - 0.049 13.6 2.2 0.57 10.2 0.2 2.4 2 0 0 2 2 2 0 Class II MHC-associated invariant chain trimerisation domain DUF2897 PF11446.8 EGC29039.1 - 0.11 12.4 1.4 0.75 9.7 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2897) Hexapep PF00132.24 EGC29040.1 - 3.9e-11 42.2 9.7 0.00038 20.1 0.0 4.4 3 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGC29040.1 - 2.5e-05 23.9 7.6 0.00015 21.5 2.6 3.7 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGC29040.1 - 0.0044 15.2 0.8 0.0054 14.9 0.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGC29040.1 - 0.012 14.6 1.5 0.07 12.0 1.0 2.0 1 1 1 2 2 2 0 L-fucokinase WYL_3 PF18488.1 EGC29040.1 - 0.14 12.6 0.3 0.22 11.9 0.3 1.3 1 0 0 1 1 1 0 WYL domain Dicty_CTDC PF00526.18 EGC29041.1 - 1.1e-23 82.7 73.9 7.8e-09 35.3 13.6 10.2 9 1 1 10 10 10 6 Dictyostelium (slime mold) repeat WD40 PF00400.32 EGC29042.1 - 7e-35 118.5 9.7 2.1e-08 34.7 0.1 10.2 10 0 0 10 10 10 5 WD domain, G-beta repeat Utp12 PF04003.12 EGC29042.1 - 1.2e-24 86.7 0.1 2.2e-24 85.8 0.1 1.5 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGC29042.1 - 1.8e-21 76.2 0.7 0.00089 19.5 0.0 8.2 4 3 2 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC29042.1 - 1.6e-07 30.6 0.1 0.0093 15.0 0.0 4.0 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGC29042.1 - 0.0001 22.1 0.1 2 8.4 0.0 5.7 7 0 0 7 7 7 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.6 EGC29042.1 - 0.048 13.7 0.1 5.1 7.2 0.0 3.6 4 1 0 4 4 4 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.6 EGC29042.1 - 0.4 11.2 2.4 1 10.0 0.2 2.8 2 1 1 3 3 3 0 PQQ-like domain Hamartin PF04388.12 EGC29043.1 - 1.3 7.6 11.7 1.5 7.4 11.7 1.2 1 0 0 1 1 1 0 Hamartin protein Epimerase PF01370.21 EGC29044.1 - 1.7e-18 66.9 0.0 2.5e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC29044.1 - 2.2e-16 59.7 0.0 2.7e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC29044.1 - 1.3e-09 37.9 0.0 7.2e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC29044.1 - 3.8e-09 36.7 0.0 7.4e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC29044.1 - 6.7e-08 32.0 0.0 1e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 EGC29044.1 - 0.00018 21.5 0.0 0.00079 19.4 0.0 1.9 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGC29044.1 - 0.00042 19.8 0.0 0.0017 17.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.13 EGC29044.1 - 0.00052 19.6 0.0 0.00077 19.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family PIN7 PF18475.1 EGC29044.1 - 0.14 12.8 0.0 0.33 11.6 0.0 1.7 1 0 0 1 1 1 0 PIN domain Epimerase PF01370.21 EGC29045.1 - 1.1e-21 77.5 0.0 1.6e-21 76.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC29045.1 - 2.1e-17 63.1 0.0 2.7e-17 62.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC29045.1 - 7.8e-15 55.1 0.0 1.4e-13 50.9 0.0 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGC29045.1 - 2e-11 43.6 0.0 3e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGC29045.1 - 2.6e-07 30.7 0.0 5.5e-07 29.6 0.0 1.7 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGC29045.1 - 2.4e-05 23.6 0.0 0.00019 20.7 0.0 2.1 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGC29045.1 - 9.7e-05 22.0 0.0 0.00016 21.3 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EGC29045.1 - 0.00047 20.1 0.1 0.0039 17.1 0.0 2.3 2 1 0 2 2 2 1 KR domain adh_short PF00106.25 EGC29045.1 - 0.0051 16.3 0.0 0.011 15.2 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ThiC_Rad_SAM PF01964.18 EGC29045.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.2 1 0 0 1 1 1 0 Radical SAM ThiC family ECH_1 PF00378.20 EGC29045.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Epimerase PF01370.21 EGC29046.1 - 1.4e-19 70.5 0.0 2.9e-19 69.5 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC29046.1 - 1e-16 60.8 0.0 1.3e-16 60.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC29046.1 - 5e-12 45.9 0.0 1.1e-10 41.4 0.0 2.1 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGC29046.1 - 1.7e-09 37.3 0.0 2.6e-09 36.7 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGC29046.1 - 2.4e-08 34.1 0.0 5.1e-08 33.0 0.0 1.6 2 0 0 2 2 2 1 NAD(P)H-binding KR PF08659.10 EGC29046.1 - 6.2e-06 26.2 0.0 2.2e-05 24.5 0.0 1.9 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGC29046.1 - 0.00011 21.8 0.0 0.00026 20.6 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.25 EGC29046.1 - 0.00019 20.9 0.1 0.00045 19.7 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.15 EGC29046.1 - 0.0069 15.5 0.0 0.019 14.1 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Insulin_TMD PF17870.1 EGC29047.1 - 0.00072 19.6 3.2 0.0023 18.0 3.2 1.9 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment NapE PF06796.11 EGC29047.1 - 0.73 9.4 3.2 1.4 8.5 3.2 1.4 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE DUF5408 PF17402.2 EGC29047.1 - 0.96 9.4 5.4 2.4 8.1 5.4 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5408) Epimerase PF01370.21 EGC29048.1 - 1.2e-20 74.1 0.0 1.7e-20 73.5 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC29048.1 - 1.8e-17 63.3 0.0 2.2e-17 63.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC29048.1 - 5.1e-11 42.5 0.0 2e-10 40.6 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC29048.1 - 2.8e-10 40.4 0.0 4.3e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC29048.1 - 1.4e-08 34.2 0.0 2.2e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 EGC29048.1 - 0.0069 16.3 0.0 0.047 13.6 0.0 2.0 1 1 0 1 1 1 1 KR domain NmrA PF05368.13 EGC29048.1 - 0.0083 15.7 0.0 0.012 15.2 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGC29048.1 - 0.019 14.1 0.0 0.035 13.3 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EGC29048.1 - 0.12 11.9 0.0 0.25 10.8 0.0 1.5 1 0 0 1 1 1 0 short chain dehydrogenase DnaJ PF00226.31 EGC29049.1 - 6e-23 80.7 0.4 1.6e-22 79.4 0.4 1.8 1 0 0 1 1 1 1 DnaJ domain RB_B PF01857.20 EGC29049.1 - 0.11 12.5 1.2 0.21 11.6 0.2 2.0 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain Pfk_N PF18468.1 EGC29049.1 - 0.15 12.5 2.4 0.71 10.3 0.2 2.7 2 1 1 3 3 3 0 Phosphofructokinase N-terminal domain yeast Astro_capsid_p PF12226.8 EGC29049.1 - 0.54 9.4 20.6 1.1 8.4 20.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein COPI_C PF06957.11 EGC29049.1 - 7.8 5.1 14.1 13 4.4 14.1 1.3 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus HA2 PF04408.23 EGC29050.1 - 4e-18 65.7 0.2 3.3e-17 62.7 0.0 2.7 3 0 0 3 3 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGC29050.1 - 1.2e-15 57.8 3.5 2.9e-15 56.6 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGC29050.1 - 1.7e-13 50.7 0.0 6.8e-13 48.8 0.0 2.1 2 0 0 2 2 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RWD PF05773.22 EGC29050.1 - 1e-11 45.2 1.6 1e-11 45.2 1.6 3.1 4 0 0 4 4 3 1 RWD domain DEAD PF00270.29 EGC29050.1 - 1.3e-10 41.3 0.0 3.5e-10 39.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase DND1_DSRM PF14709.7 EGC29050.1 - 3.8e-05 23.9 0.3 0.00027 21.1 0.5 2.3 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.6 EGC29050.1 - 0.0015 18.8 2.6 0.021 15.1 1.6 3.3 2 1 0 2 2 2 1 AAA domain dsrm PF00035.26 EGC29050.1 - 0.023 15.4 0.6 0.092 13.5 0.6 2.1 1 0 0 1 1 1 0 Double-stranded RNA binding motif dsRBD2 PF17842.1 EGC29050.1 - 0.028 14.6 0.6 0.028 14.6 0.6 3.7 3 1 1 4 4 3 0 Double-stranded RNA binding domain 2 UBA PF00627.31 EGC29050.1 - 0.039 13.9 0.0 0.093 12.7 0.0 1.7 1 0 0 1 1 1 0 UBA/TS-N domain AAA_19 PF13245.6 EGC29050.1 - 0.066 13.5 0.0 0.25 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain SR-25 PF10500.9 EGC29050.1 - 5.3 6.6 22.1 0.13 11.9 8.4 2.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TRAP-gamma PF07074.12 EGC29051.1 - 9.9e-29 100.1 9.0 1.2e-28 99.8 9.0 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) bPH_3 PF14470.6 EGC29051.1 - 0.0057 17.0 0.6 0.28 11.6 0.1 2.7 2 1 1 3 3 3 1 Bacterial PH domain DIOX_N PF14226.6 EGC29052.1 - 4.2e-05 24.3 0.0 0.00015 22.5 0.0 1.9 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC29052.1 - 0.00022 21.7 0.0 0.00039 20.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DrrA_P4M PF14860.6 EGC29053.1 - 0.066 13.1 2.4 0.34 10.8 0.7 2.3 2 1 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain WD40 PF00400.32 EGC29054.1 - 9.4e-39 130.7 19.1 2e-05 25.3 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC29054.1 - 1.4e-12 47.7 0.0 0.054 13.8 0.0 5.3 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC29054.1 - 4.7e-05 22.9 0.0 0.00048 19.5 0.0 2.6 2 1 0 2 2 2 1 WD40-like domain eIF2A PF08662.11 EGC29054.1 - 0.0014 18.6 0.0 2.2 8.1 0.0 2.8 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGC29054.1 - 0.008 14.9 0.2 1.7 7.2 0.0 2.5 2 1 0 2 2 2 2 Nucleoporin Nup120/160 CRF PF00473.17 EGC29054.1 - 0.65 10.1 2.1 1.2 9.2 2.1 1.4 1 0 0 1 1 1 0 Corticotropin-releasing factor family RRM_1 PF00076.22 EGC29055.1 - 8e-20 70.4 0.3 8.5e-20 70.4 0.3 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC29055.1 - 0.002 18.1 0.0 0.0025 17.8 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_7 PF16367.5 EGC29055.1 - 0.0036 17.4 0.1 0.0095 16.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif Sod_Fe_C PF02777.18 EGC29056.1 - 3e-30 104.4 2.1 3.2e-29 101.1 0.2 2.3 1 1 1 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGC29056.1 - 7.9e-10 39.1 0.7 7.9e-10 39.1 0.7 2.1 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain EMP70 PF02990.16 EGC29057.1 - 9.2e-158 526.1 21.4 9.2e-158 526.1 21.4 1.9 2 0 0 2 2 2 1 Endomembrane protein 70 CagX PF03524.15 EGC29057.1 - 0.046 13.5 0.1 0.077 12.7 0.1 1.2 1 0 0 1 1 1 0 Conjugal transfer protein PALP PF00291.25 EGC29058.1 - 1.5e-83 280.7 0.0 8.1e-74 248.7 0.1 3.7 3 1 0 3 3 3 2 Pyridoxal-phosphate dependent enzyme ACT_4 PF13291.6 EGC29058.1 - 0.045 14.3 0.0 1.7 9.3 0.0 2.8 2 0 0 2 2 2 0 ACT domain ACT_5 PF13710.6 EGC29058.1 - 0.093 12.6 0.3 1.9 8.4 0.2 2.5 2 0 0 2 2 2 0 ACT domain PP_M1 PF03012.14 EGC29060.1 - 0.028 14.0 3.4 0.036 13.6 3.4 1.2 1 0 0 1 1 1 0 Phosphoprotein Mucin PF01456.17 EGC29060.1 - 0.043 13.8 3.8 0.065 13.2 3.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Goodbye PF17109.5 EGC29060.1 - 0.11 13.0 3.9 2.2 8.7 0.8 2.7 2 1 1 3 3 3 0 fungal STAND N-terminal Goodbye domain DUF4519 PF15012.6 EGC29060.1 - 0.15 12.3 0.0 0.15 12.3 0.0 3.4 4 0 0 4 4 4 0 Domain of unknown function (DUF4519) Lin-8 PF03353.15 EGC29060.1 - 0.16 11.5 10.4 0.014 15.0 5.5 1.6 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist CLN3 PF02487.17 EGC29060.1 - 0.33 10.0 5.5 0.12 11.5 1.4 1.8 2 0 0 2 2 2 0 CLN3 protein Rtf2 PF04641.12 EGC29060.1 - 5.2 6.4 11.8 9.5 5.5 11.8 1.3 1 0 0 1 1 1 0 Rtf2 RING-finger Striatin PF08232.12 EGC29060.1 - 5.3 7.6 12.7 0.35 11.5 7.7 1.5 2 0 0 2 2 2 0 Striatin family PPR_3 PF13812.6 EGC29061.1 - 0.0032 17.5 0.7 0.0032 17.5 0.7 2.1 2 0 0 2 2 2 1 Pentatricopeptide repeat domain NUDIX PF00293.28 EGC29062.1 - 8.2e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FNIP PF05725.12 EGC29063.1 - 6.2e-49 163.9 50.8 2.1e-06 27.8 0.2 11.6 1 1 15 17 17 17 17 FNIP Repeat Pro_isomerase PF00160.21 EGC29063.1 - 0.0016 18.7 0.2 38 4.5 0.0 5.9 9 0 0 9 9 9 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD PvlArgDC PF01862.16 EGC29063.1 - 1.5 8.6 2.7 1.1e+02 2.6 0.1 3.6 4 0 0 4 4 4 0 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) Acetyltransf_1 PF00583.25 EGC29065.1 - 1.8e-06 28.2 0.0 0.00093 19.4 0.0 2.9 3 0 0 3 3 3 2 Acetyltransferase (GNAT) family RAP PF08373.10 EGC29065.1 - 0.0039 17.2 0.5 1.2 9.3 0.1 3.0 2 0 0 2 2 2 1 RAP domain Acetyltransf_7 PF13508.7 EGC29065.1 - 0.0039 17.6 0.0 0.011 16.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC29065.1 - 0.017 14.6 1.7 0.14 11.6 0.0 2.4 2 0 0 2 2 2 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGC29065.1 - 0.063 13.4 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.7 EGC29065.1 - 0.079 12.9 0.0 0.43 10.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain AFG1_ATPase PF03969.16 EGC29066.1 - 4.4e-104 348.3 0.7 8.5e-100 334.1 0.1 2.6 2 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.6 EGC29066.1 - 0.00033 21.1 0.1 0.15 12.4 0.0 3.4 3 1 0 4 4 4 1 AAA ATPase domain ABC_tran PF00005.27 EGC29066.1 - 0.034 14.7 0.1 0.58 10.7 0.0 2.9 1 1 1 2 2 2 0 ABC transporter AAA_22 PF13401.6 EGC29066.1 - 0.036 14.3 0.0 0.25 11.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain DUF2009 PF09418.10 EGC29067.1 - 2.8e-208 692.6 0.4 3.6e-208 692.2 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) Flag1_repress PF03614.13 EGC29067.1 - 0.00048 20.0 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Repressor of phase-1 flagellin zf-B_box PF00643.24 EGC29067.1 - 0.00057 20.0 7.9 0.00057 20.0 7.9 1.7 2 0 0 2 2 2 1 B-box zinc finger Sporozoite_P67 PF05642.11 EGC29067.1 - 0.47 8.5 2.9 0.72 7.9 2.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Spt5_N PF11942.8 EGC29067.1 - 0.56 11.2 10.0 4.6 8.3 1.9 3.1 3 0 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal BSP_II PF05432.11 EGC29067.1 - 1.8 8.2 10.7 3.3 7.3 10.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DHHC PF01529.20 EGC29068.1 - 1e-30 106.5 26.2 1e-30 106.5 26.2 3.5 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.6 EGC29068.1 - 0.023 15.1 2.9 0.023 15.1 2.9 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1272 PF06906.11 EGC29068.1 - 0.52 10.5 6.0 1 9.5 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Oxidored_FMN PF00724.20 EGC29069.1 - 0.0077 15.5 0.0 0.0086 15.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family zf-CCHC PF00098.23 EGC29070.1 - 8.6e-06 25.6 1.1 1.3e-05 25.0 1.1 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGC29070.1 - 0.0023 17.7 0.2 0.0039 17.0 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1825 PF08855.10 EGC29070.1 - 0.015 15.2 0.1 0.039 13.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) Macoilin PF09726.9 EGC29070.1 - 0.18 10.3 35.2 0.025 13.2 20.7 2.1 2 0 0 2 2 2 0 Macoilin family Ly49 PF08391.10 EGC29071.1 - 0.016 15.5 2.6 0.047 14.0 0.2 2.4 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Sigma_reg_N PF13800.6 EGC29071.1 - 0.024 14.9 1.6 0.024 14.9 1.6 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal TMEM154 PF15102.6 EGC29071.1 - 0.026 14.4 0.7 0.06 13.2 0.7 1.6 1 0 0 1 1 1 0 TMEM154 protein family Baculo_11_kDa PF06143.11 EGC29071.1 - 0.052 13.1 2.7 0.35 10.5 1.0 2.8 3 0 0 3 3 3 0 Baculovirus 11 kDa family PRIMA1 PF16101.5 EGC29071.1 - 0.055 13.5 0.1 0.11 12.5 0.1 1.5 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 EphA2_TM PF14575.6 EGC29071.1 - 0.1 13.5 0.2 0.28 12.1 0.2 1.7 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Orf78 PF06024.12 EGC29071.1 - 2.1 8.7 9.9 0.13 12.5 2.2 2.6 2 1 0 2 2 2 0 Orf78 (ac78) Cpn60_TCP1 PF00118.24 EGC29072.1 - 3.4e-94 316.2 5.0 4.2e-94 315.9 5.0 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.22 EGC29073.1 - 1.5e-55 187.2 0.0 1.7e-55 187.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC29073.1 - 1.1e-19 70.8 0.0 1.7e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC29073.1 - 2.4e-08 33.6 0.0 2.5e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC29073.1 - 0.0003 20.8 0.0 0.00051 20.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC29073.1 - 0.00046 20.1 0.0 0.3 11.0 0.1 2.2 1 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC29073.1 - 0.0013 18.3 0.0 0.053 13.0 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Septin PF00735.18 EGC29073.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.10 EGC29073.1 - 0.089 12.2 0.0 0.12 11.9 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.16 EGC29073.1 - 0.096 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family PglD_N PF17836.1 EGC29073.1 - 0.12 13.1 0.4 0.24 12.1 0.2 1.8 1 1 0 1 1 1 0 PglD N-terminal domain ParA PF10609.9 EGC29073.1 - 0.18 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Peptidase_M76 PF09768.9 EGC29074.1 - 1e-51 175.1 1.2 1.3e-51 174.7 1.2 1.1 1 0 0 1 1 1 1 Peptidase M76 family SprT-like PF10263.9 EGC29074.1 - 0.11 12.4 0.3 0.25 11.2 0.3 1.5 1 1 0 1 1 1 0 SprT-like family Pkinase PF00069.25 EGC29075.1 - 6.9e-71 238.7 0.0 6.9e-71 238.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29075.1 - 4.5e-45 153.9 0.0 9.2e-45 152.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC29075.1 - 1.3e-07 30.8 0.0 1.3e-07 30.8 0.0 2.6 3 0 0 3 3 3 1 Fungal protein kinase Kdo PF06293.14 EGC29075.1 - 0.045 13.1 0.0 0.045 13.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC29075.1 - 0.11 12.1 0.0 0.11 12.1 0.0 2.7 3 0 0 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 APH PF01636.23 EGC29075.1 - 0.12 12.2 0.0 0.98 9.3 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family LMBR1 PF04791.16 EGC29075.1 - 0.78 8.6 9.4 1.3 7.9 9.4 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EMC3_TMCO1 PF01956.16 EGC29075.1 - 6.7 6.4 11.8 11 5.7 4.6 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like AAA_18 PF13238.6 EGC29076.1 - 2.2e-12 47.6 0.4 3.6e-12 46.9 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGC29076.1 - 4.4e-12 46.6 0.0 7.1e-12 45.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGC29076.1 - 1.1e-09 38.6 0.0 1.5e-09 38.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EGC29076.1 - 0.0004 20.1 0.1 0.0018 17.9 0.0 1.9 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_14 PF13173.6 EGC29076.1 - 0.0032 17.5 0.1 0.0055 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain P-mevalo_kinase PF04275.14 EGC29076.1 - 0.0058 16.6 0.0 0.057 13.4 0.0 2.2 1 1 0 1 1 1 1 Phosphomevalonate kinase AAA_22 PF13401.6 EGC29076.1 - 0.12 12.7 0.1 0.19 12.0 0.1 1.6 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.22 EGC29077.1 - 3e-51 171.1 8.5 5.7e-15 54.9 0.0 5.7 5 1 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC29077.1 - 9.7e-12 44.9 1.8 0.013 15.6 0.1 4.8 4 0 0 4 4 4 3 RNA recognition motif Nup35_RRM_2 PF14605.6 EGC29077.1 - 0.022 14.8 0.2 14 5.7 0.0 3.5 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Roc PF08477.13 EGC29078.1 - 5.3e-06 26.6 0.2 2e-05 24.8 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC29078.1 - 9.2e-05 22.5 0.3 0.001 19.2 0.3 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Ras PF00071.22 EGC29078.1 - 0.00029 20.5 0.1 0.0034 17.0 0.0 2.2 2 0 0 2 2 2 1 Ras family WD40 PF00400.32 EGC29079.1 - 1.3e-17 63.8 6.8 0.01 16.7 0.1 5.8 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC29079.1 - 8.2e-07 29.2 0.1 3.7 7.9 0.0 5.0 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain Mcl1_mid PF12341.8 EGC29079.1 - 0.00013 21.5 0.6 0.00037 19.9 0.6 1.8 1 1 0 1 1 1 1 Minichromosome loss protein, Mcl1, middle region eIF2A PF08662.11 EGC29079.1 - 0.00024 21.0 0.7 0.42 10.5 0.0 3.8 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A DUF4834 PF16118.5 EGC29079.1 - 0.0029 18.5 1.2 0.007 17.3 1.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) PD40 PF07676.12 EGC29079.1 - 0.006 16.5 0.7 28 4.8 0.0 5.0 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat MAP17 PF15807.5 EGC29079.1 - 0.0096 16.2 0.2 0.019 15.2 0.2 1.4 1 0 0 1 1 1 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 SdiA-regulated PF06977.11 EGC29079.1 - 0.037 13.3 0.0 0.24 10.6 0.0 2.3 2 1 1 3 3 3 0 SdiA-regulated RP-C_C PF11800.8 EGC29079.1 - 0.21 11.6 0.7 0.33 11.0 0.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region PH_12 PF16457.5 EGC29079.1 - 8.1 7.0 10.3 1.3 9.6 0.2 3.6 3 2 1 4 4 4 0 Pleckstrin homology domain 14-3-3 PF00244.20 EGC29080.1 - 1.1e-106 355.4 4.8 1.3e-106 355.1 4.8 1.1 1 0 0 1 1 1 1 14-3-3 protein DUF722 PF05263.11 EGC29080.1 - 0.05 13.8 3.4 0.074 13.3 2.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF722) Protoglobin PF11563.8 EGC29080.1 - 0.069 13.0 0.2 3.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Protoglobin AAA_19 PF13245.6 EGC29081.1 - 0.045 14.1 0.0 0.095 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.18 EGC29081.1 - 0.16 11.3 0.0 0.43 9.9 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family Viral_helicase1 PF01443.18 EGC29081.1 - 0.26 11.0 0.0 0.26 11.0 0.0 2.4 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase Isochorismatase PF00857.20 EGC29083.1 - 1.4e-30 106.7 0.0 1.7e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family FNIP PF05725.12 EGC29084.1 - 4e-79 260.6 83.5 2.4e-11 43.6 3.6 12.2 11 1 1 12 12 12 12 FNIP Repeat LRR_8 PF13855.6 EGC29084.1 - 0.00031 20.4 6.0 0.15 11.8 0.0 5.2 3 1 1 4 4 4 1 Leucine rich repeat DUF1769 PF08588.10 EGC29084.1 - 0.074 13.3 11.5 25 5.1 0.0 7.4 5 1 5 10 10 10 0 Protein of unknown function (DUF1769) Ribosomal_L11_N PF03946.14 EGC29084.1 - 0.17 11.7 0.2 15 5.6 0.0 3.7 3 1 1 4 4 4 0 Ribosomal protein L11, N-terminal domain TbpB_C PF17483.2 EGC29084.1 - 0.31 11.4 6.2 19 5.7 0.0 5.5 3 1 0 4 4 4 0 C-lobe handle domain of Tf-binding protein B COG6 PF06419.11 EGC29085.1 - 2.3e-193 643.9 35.4 2.6e-193 643.7 35.4 1.0 1 0 0 1 1 1 1 Conserved oligomeric complex COG6 PSII_Pbs27 PF13326.6 EGC29085.1 - 0.024 14.9 0.7 12 6.2 0.1 3.1 2 1 1 3 3 3 0 Photosystem II Pbs27 DUF5344 PF17279.2 EGC29085.1 - 0.044 14.4 1.2 0.044 14.4 1.2 3.9 3 2 0 3 3 3 0 Family of unknown function (DUF5344) DUF948 PF06103.11 EGC29085.1 - 0.087 13.1 0.6 0.72 10.2 0.5 2.6 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) YicC_N PF03755.13 EGC29085.1 - 0.14 12.6 4.0 0.15 12.5 0.9 2.5 2 1 0 2 2 2 0 YicC-like family, N-terminal region DASH_Dam1 PF08653.10 EGC29085.1 - 1.1 9.2 5.8 0.93 9.3 0.6 3.5 2 1 1 3 3 3 0 DASH complex subunit Dam1 Laminin_II PF06009.12 EGC29085.1 - 1.6 8.8 8.0 0.61 10.1 1.6 3.4 3 0 0 3 3 3 0 Laminin Domain II TRAM_LAG1_CLN8 PF03798.16 EGC29086.1 - 5.7e-26 91.5 13.1 5.7e-26 91.5 13.1 1.9 2 0 0 2 2 2 1 TLC domain p450 PF00067.22 EGC29087.1 - 2e-76 257.6 1.5 2.3e-76 257.4 1.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 EGC29088.1 - 3.1e-29 100.9 12.4 6.2e-14 51.9 0.8 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC29088.1 - 1.5e-27 95.6 7.6 2e-14 53.5 0.2 4.3 3 1 1 4 4 4 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGC29088.1 - 0.00053 20.0 4.4 0.4 10.7 0.1 3.5 2 2 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EGC29088.1 - 0.0015 18.7 0.6 1.7 8.9 0.0 3.2 2 1 1 3 3 3 2 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_4 PF13837.6 EGC29088.1 - 0.016 15.6 15.5 0.11 12.8 0.7 4.0 3 1 0 4 4 4 0 Myb/SANT-like DNA-binding domain DUF445 PF04286.12 EGC29088.1 - 0.052 13.4 1.4 1.8 8.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Ribosomal_L18_c PF14204.6 EGC29088.1 - 0.19 12.7 2.8 0.29 12.1 0.7 2.3 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Atg29_N PF18388.1 EGC29088.1 - 0.42 10.5 9.5 2.1 8.2 0.5 3.6 3 0 0 3 3 3 0 Atg29 N-terminal domain MADF_DNA_bdg PF10545.9 EGC29088.1 - 0.5 10.7 6.5 11 6.4 0.1 3.3 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Myb_DNA-bind_5 PF13873.6 EGC29088.1 - 0.71 10.0 5.4 46 4.2 0.4 3.8 2 1 0 3 3 3 0 Myb/SANT-like DNA-binding domain SAGA-Tad1 PF12767.7 EGC29088.1 - 0.72 9.6 5.7 0.94 9.2 5.3 1.5 1 1 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit SH3_1 PF00018.28 EGC29089.1 - 1.9e-11 43.3 0.0 2.2e-11 43.2 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGC29089.1 - 2e-11 43.4 0.0 2.2e-11 43.3 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGC29089.1 - 5e-10 39.1 0.0 5.6e-10 38.9 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC29090.1 - 7.7e-08 31.9 0.0 1.2e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGC29090.1 - 5e-05 23.1 0.0 7.4e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC29090.1 - 0.0022 17.6 0.0 0.0045 16.6 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TetR_N PF00440.23 EGC29090.1 - 0.08 12.8 0.1 0.15 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Plant_all_beta PF10532.9 EGC29090.1 - 0.87 9.9 6.0 0.73 10.1 3.6 2.0 1 1 0 2 2 2 0 Plant specific N-all beta domain KLRAQ PF10205.9 EGC29090.1 - 4.5 7.6 12.6 0.1 12.8 4.3 2.3 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein Glyco_hydro_63 PF03200.16 EGC29091.1 - 0.0018 17.2 0.6 0.0029 16.4 0.6 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain BAR PF03114.18 EGC29091.1 - 0.021 14.5 4.2 0.04 13.6 4.2 1.5 1 0 0 1 1 1 0 BAR domain IPP-2 PF04979.14 EGC29092.1 - 1.1e-22 81.2 22.7 1.1e-22 81.2 22.7 2.5 2 1 0 2 2 2 1 Protein phosphatase inhibitor 2 (IPP-2) DUF2201_N PF13203.6 EGC29092.1 - 0.079 12.5 4.2 0.11 12.0 4.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2393 PF09624.10 EGC29092.1 - 4.4 7.3 5.2 0.51 10.3 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2393) UQ_con PF00179.26 EGC29093.1 - 7.8e-44 148.7 0.0 8.4e-44 148.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC29093.1 - 0.026 14.8 0.1 0.03 14.6 0.1 1.2 1 0 0 1 1 1 0 RWD domain Prok-E2_B PF14461.6 EGC29093.1 - 0.035 13.8 0.0 0.041 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Pro_isomerase PF00160.21 EGC29094.1 - 2.1e-37 128.8 0.0 2.8e-37 128.4 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ig_Tie2_1 PF10430.9 EGC29094.1 - 0.097 13.1 0.0 0.16 12.4 0.0 1.3 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 DHHC PF01529.20 EGC29095.1 - 1.5e-40 138.4 8.8 2.2e-40 137.9 8.8 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Wzy_C PF04932.15 EGC29095.1 - 0.0033 17.1 0.5 0.0044 16.7 0.5 1.2 1 0 0 1 1 1 1 O-Antigen ligase DUF3675 PF12428.8 EGC29095.1 - 0.013 16.1 6.7 0.013 16.1 6.7 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) zf-ribbon_3 PF13248.6 EGC29095.1 - 0.025 14.0 4.1 0.049 13.1 4.1 1.5 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGC29095.1 - 0.25 11.1 6.4 0.48 10.2 6.4 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF4834 PF16118.5 EGC29095.1 - 0.47 11.4 6.3 0.42 11.6 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF1272 PF06906.11 EGC29095.1 - 4.7 7.4 9.7 20 5.4 0.8 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1272) FYVE PF01363.21 EGC29095.1 - 9 6.5 13.8 19 5.5 13.8 1.6 1 1 0 1 1 1 0 FYVE zinc finger IMD PF08397.11 EGC29096.1 - 1.5e-13 50.7 9.8 2e-13 50.3 9.8 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_1 PF00018.28 EGC29096.1 - 3.1e-13 49.1 0.0 7.5e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC29096.1 - 1.7e-09 37.3 0.0 3.2e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC29096.1 - 3.7e-07 29.7 0.0 8e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BAR_3 PF16746.5 EGC29096.1 - 0.0003 20.6 16.4 0.05 13.3 8.3 2.2 1 1 1 2 2 2 2 BAR domain of APPL family Cytochrom_B562 PF07361.11 EGC29096.1 - 0.058 14.0 6.4 0.33 11.6 3.3 2.5 2 0 0 2 2 2 0 Cytochrome b562 TSC22 PF01166.18 EGC29096.1 - 0.072 13.4 0.7 0.072 13.4 0.7 2.8 3 0 0 3 3 3 0 TSC-22/dip/bun family DUF4790 PF16037.5 EGC29096.1 - 0.48 10.9 6.1 0.22 12.0 1.5 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4790) zf-C3Hc3H PF13891.6 EGC29097.1 - 5.6e-10 39.4 6.2 5.6e-10 39.4 6.2 1.8 2 0 0 2 2 2 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.8 EGC29097.1 - 0.00029 20.5 8.3 0.014 15.1 0.6 2.7 2 1 0 2 2 2 2 CCCH zinc finger in TRM13 protein DUF2205 PF10224.9 EGC29097.1 - 0.0011 18.9 1.9 0.0032 17.4 1.9 1.7 1 0 0 1 1 1 1 Short coiled-coil protein CENP-F_leu_zip PF10473.9 EGC29097.1 - 0.0034 17.4 2.3 0.0034 17.4 2.3 2.2 2 0 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4242 PF14026.6 EGC29097.1 - 0.018 15.2 1.3 0.027 14.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4242) ZapB PF06005.12 EGC29097.1 - 0.021 15.3 1.8 0.021 15.3 1.8 3.2 3 0 0 3 3 3 0 Cell division protein ZapB zf-primase PF09329.11 EGC29097.1 - 0.036 13.9 1.7 0.036 13.9 1.7 2.2 2 0 0 2 2 2 0 Primase zinc finger HALZ PF02183.18 EGC29097.1 - 1.5 9.1 9.2 1.9 8.7 1.0 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper GATA PF00320.27 EGC29098.1 - 4.8e-16 58.1 4.0 1e-15 57.0 4.0 1.6 1 0 0 1 1 1 1 GATA zinc finger BSP_II PF05432.11 EGC29099.1 - 6.6 6.3 15.4 12 5.5 15.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) WD40 PF00400.32 EGC29100.1 - 1.2e-29 101.9 14.7 1.2e-08 35.5 0.2 7.2 6 1 1 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.11 EGC29100.1 - 4.1e-06 26.8 0.0 3.7e-05 23.7 0.0 2.1 1 1 0 2 2 2 1 Eukaryotic translation initiation factor eIF2A ANAPC4_WD40 PF12894.7 EGC29100.1 - 3.7e-05 23.9 0.0 22 5.4 0.0 4.8 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC29100.1 - 9.9e-05 21.8 0.0 0.51 9.6 0.0 3.1 3 0 0 3 3 3 2 WD40-like domain Nup160 PF11715.8 EGC29100.1 - 0.0019 16.9 0.1 0.49 9.0 0.0 2.3 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGC29100.1 - 0.048 12.6 0.2 1.7 7.5 0.1 3.3 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DnaJ PF00226.31 EGC29101.1 - 2.2e-14 53.3 0.4 8.5e-14 51.4 0.4 2.0 1 0 0 1 1 1 1 DnaJ domain GYF_2 PF14237.6 EGC29101.1 - 1.1e-12 47.5 0.1 2.6e-12 46.4 0.1 1.7 1 0 0 1 1 1 1 GYF domain 2 KTSC PF13619.6 EGC29101.1 - 0.036 13.9 0.3 1.9 8.4 0.0 2.6 2 0 0 2 2 2 0 KTSC domain RPN5_C PF18098.1 EGC29101.1 - 2.6 8.3 4.6 12 6.1 0.9 3.1 2 0 0 2 2 2 0 26S proteasome regulatory subunit RPN5 C-terminal domain RIH_assoc PF08454.11 EGC29101.1 - 4.6 7.2 10.0 1.7 8.5 0.1 4.6 4 0 0 4 4 4 0 RyR and IP3R Homology associated FNIP PF05725.12 EGC29102.1 - 1.1e-44 150.4 45.4 5.2e-06 26.5 0.5 9.6 1 1 8 12 12 12 12 FNIP Repeat RNaseH_like PF04308.12 EGC29102.1 - 0.12 12.3 0.0 60 3.5 0.0 4.4 6 1 1 7 7 7 0 Ribonuclease H-like UPF0564 PF10595.9 EGC29102.1 - 0.16 11.0 2.0 1.5e+02 1.2 0.0 5.1 7 0 0 7 7 7 0 Uncharacterised protein family UPF0564 7tm_3 PF00003.22 EGC29103.1 - 6.5e-34 117.7 29.3 1.2e-33 116.9 29.3 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC29103.1 - 5.2e-15 55.2 13.6 5.2e-15 55.2 13.6 1.7 2 0 0 2 2 2 1 ABC transporter substrate-binding protein PnrA-like GP3_package PF16677.5 EGC29104.1 - 0.054 13.6 0.1 2.9 8.1 0.1 2.4 1 1 0 1 1 1 0 DNA-packaging protein gp3 P_proprotein PF01483.20 EGC29104.1 - 0.076 13.1 0.0 0.15 12.1 0.0 1.6 1 0 0 1 1 1 0 Proprotein convertase P-domain Glycos_transf_2 PF00535.26 EGC29105.1 - 2e-16 60.3 0.1 4.6e-16 59.1 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGC29105.1 - 0.00013 22.0 0.0 0.00032 20.7 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Tau95 PF09734.9 EGC29108.1 - 2e-35 122.6 0.2 2e-35 122.6 0.2 3.1 3 1 0 3 3 3 1 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain Tau95_N PF17682.1 EGC29108.1 - 3.4e-28 98.4 0.0 3.4e-28 98.4 0.0 3.3 3 0 0 3 3 3 1 Tau95 Triple barrel domain Sel1 PF08238.12 EGC29109.1 - 6.3e-09 36.2 0.8 0.015 16.0 0.2 4.6 4 0 0 4 4 4 2 Sel1 repeat TPR_17 PF13431.6 EGC29109.1 - 1.4e-05 25.2 1.5 5.8 7.5 0.0 6.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC29109.1 - 0.0092 15.8 1.4 0.22 11.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGC29109.1 - 0.028 14.7 0.0 0.14 12.5 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC29109.1 - 0.037 14.7 1.4 3.8 8.4 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC29109.1 - 5.6 7.3 8.0 7.1 7.0 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC29109.1 - 6.8 7.2 16.3 3.5 8.1 0.0 6.3 7 0 0 7 7 7 0 Tetratricopeptide repeat Tmpp129 PF10272.9 EGC29110.1 - 0.023 14.0 0.9 0.028 13.8 0.9 1.0 1 0 0 1 1 1 0 Putative transmembrane protein precursor PH PF00169.29 EGC29112.1 - 0.015 15.8 0.0 0.031 14.8 0.0 1.6 1 0 0 1 1 1 0 PH domain LRR_6 PF13516.6 EGC29113.1 - 7.8e-53 172.1 39.9 1.7e-06 27.6 0.5 13.8 14 0 0 14 14 14 11 Leucine Rich repeat LRR_1 PF00560.33 EGC29113.1 - 0.002 18.4 20.5 56 4.9 0.0 10.6 11 1 0 11 11 11 0 Leucine Rich Repeat F-box-like PF12937.7 EGC29113.1 - 0.023 14.6 0.2 0.047 13.6 0.2 1.4 1 0 0 1 1 1 0 F-box-like SPX PF03105.19 EGC29113.1 - 6.3 6.6 22.3 13 5.5 22.3 1.5 1 0 0 1 1 1 0 SPX domain Menin PF05053.13 EGC29113.1 - 7.1 4.8 9.3 10 4.3 8.4 1.8 2 0 0 2 2 2 0 Menin ketoacyl-synt PF00109.26 EGC29114.1 - 9.1e-71 238.4 0.0 7.8e-70 235.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC29114.1 - 2.1e-46 158.9 0.0 3.1e-46 158.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGC29114.1 - 8.5e-33 113.8 0.0 1.5e-32 112.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC29114.1 - 9.4e-33 113.7 0.0 1.4e-32 113.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.22 EGC29114.1 - 2.7e-28 98.4 0.0 7.8e-28 96.9 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Chal_sti_synt_C PF02797.15 EGC29114.1 - 7.2e-21 74.8 0.1 1.1e-19 70.9 0.0 2.5 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGC29114.1 - 4.3e-17 62.3 0.5 1.2e-16 60.8 0.1 1.9 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain ADH_zinc_N PF00107.26 EGC29114.1 - 3.7e-15 56.1 0.0 6.6e-14 52.0 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC29114.1 - 1.3e-13 52.1 0.0 6e-13 50.0 0.0 2.2 3 0 0 3 3 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.12 EGC29114.1 - 4.6e-13 49.1 0.4 1.1e-12 47.9 0.4 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein PP-binding PF00550.25 EGC29114.1 - 1.8e-10 41.0 0.1 4.6e-10 39.7 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site KAsynt_C_assoc PF16197.5 EGC29114.1 - 6.1e-10 39.5 0.1 2.4e-09 37.6 0.1 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EGC29114.1 - 8.8e-09 35.2 0.0 2.5e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.10 EGC29114.1 - 5.7e-08 32.8 0.0 1e-05 25.6 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Thiolase_N PF00108.23 EGC29114.1 - 5e-05 22.8 2.3 0.0015 17.9 0.1 2.6 3 0 0 3 3 3 1 Thiolase, N-terminal domain adh_short PF00106.25 EGC29114.1 - 0.00026 20.5 0.0 0.001 18.6 0.0 2.0 1 0 0 1 1 1 1 short chain dehydrogenase ACP_syn_III PF08545.10 EGC29114.1 - 0.012 15.5 1.5 0.3 11.0 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III CoA_trans PF01144.23 EGC29114.1 - 0.18 11.2 0.1 20 4.5 0.0 2.3 2 0 0 2 2 2 0 Coenzyme A transferase FERM_f0 PF16511.5 EGC29115.1 - 8.8e-05 22.7 0.0 0.00011 22.5 0.0 1.2 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM End_tail_spike PF12219.8 EGC29115.1 - 0.11 12.5 0.0 0.13 12.3 0.0 1.1 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase Adap_comp_sub PF00928.21 EGC29116.1 - 4.3e-89 298.4 0.0 5.4e-89 298.1 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGC29116.1 - 2.3e-09 37.3 1.5 3.9e-09 36.6 1.5 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TIR_2 PF13676.6 EGC29117.1 - 1.1e-20 74.3 0.1 9.1e-20 71.4 0.0 2.3 2 0 0 2 2 2 1 TIR domain RCC1 PF00415.18 EGC29117.1 - 5e-15 55.9 7.3 7.3e-08 32.9 0.1 4.7 5 0 0 5 5 4 3 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC29117.1 - 1.4e-09 37.5 5.3 0.0017 18.1 0.1 4.5 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat TIR PF01582.20 EGC29117.1 - 4.3e-08 33.1 0.1 1.6e-07 31.3 0.1 2.0 1 0 0 1 1 1 1 TIR domain BRCT PF00533.26 EGC29117.1 - 5.6e-07 29.9 3.2 1.6e-06 28.4 0.8 3.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC29117.1 - 2.9e-06 27.6 2.3 2.9e-06 27.6 2.3 3.1 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain Ank_2 PF12796.7 EGC29117.1 - 4.7e-06 27.1 0.0 0.0015 19.1 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) DUF1863 PF08937.11 EGC29117.1 - 0.0024 18.2 1.0 0.0024 18.2 1.0 5.3 3 2 2 5 5 5 1 MTH538 TIR-like domain (DUF1863) Ank_4 PF13637.6 EGC29117.1 - 0.012 16.2 0.0 6.1 7.6 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Ank PF00023.30 EGC29117.1 - 0.064 13.7 0.0 26 5.5 0.0 3.6 3 0 0 3 3 3 0 Ankyrin repeat Ank_5 PF13857.6 EGC29117.1 - 0.085 13.2 0.0 0.085 13.2 0.0 2.9 3 0 0 3 3 2 0 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC29117.1 - 0.088 13.4 0.1 92 4.1 0.1 4.0 3 0 0 3 3 3 0 Ankyrin repeat Myosin_head PF00063.21 EGC29118.1 - 2.2e-190 634.3 24.7 1.5e-169 565.4 14.7 2.3 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC29118.1 - 8.1e-30 103.9 2.2 8.1e-30 103.9 2.2 2.1 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGC29118.1 - 1.3e-06 27.7 5.8 5.5e-05 22.6 1.3 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 EGC29118.1 - 0.0076 16.5 0.0 0.032 14.5 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC29118.1 - 0.15 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain PCI PF01399.27 EGC29119.1 - 7.8e-06 26.4 4.0 5.1e-05 23.7 2.4 3.4 2 0 0 2 2 2 1 PCI domain NSP2-B_epitope PF14757.6 EGC29119.1 - 1.3 8.6 3.9 2.4 7.8 3.9 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein FNIP PF05725.12 EGC29120.1 - 0.00025 21.2 2.6 0.00051 20.2 1.6 2.0 2 0 0 2 2 2 1 FNIP Repeat Ste5_C PF12194.8 EGC29120.1 - 0.054 13.4 0.0 0.12 12.3 0.0 1.5 2 0 0 2 2 2 0 Protein kinase Fus3-binding SAM_1 PF00536.30 EGC29121.1 - 0.0013 19.1 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC29121.1 - 0.059 13.5 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4264 PF14084.6 EGC29122.1 - 0.05 13.2 0.1 0.48 10.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF4264) TFIIF_alpha PF05793.12 EGC29123.1 - 0.0039 15.8 49.2 0.0052 15.4 49.2 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Caldesmon PF02029.15 EGC29123.1 - 0.25 10.1 54.0 0.33 9.7 54.0 1.2 1 0 0 1 1 1 0 Caldesmon TIG PF01833.24 EGC29125.1 - 3.7e-11 42.9 8.3 0.00013 21.9 0.2 3.3 2 1 1 3 3 3 3 IPT/TIG domain PH_15 PF17339.2 EGC29125.1 - 0.043 13.7 0.7 0.16 11.9 0.1 2.2 2 1 1 3 3 3 0 PH domain Snf7 PF03357.21 EGC29126.1 - 4.1e-05 23.3 3.8 4.1e-05 23.3 3.8 1.9 1 1 1 2 2 2 1 Snf7 Bacillus_HBL PF05791.11 EGC29127.1 - 8.5e-07 29.0 13.8 8.5e-07 29.0 13.8 2.4 1 1 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) Fib_alpha PF08702.10 EGC29127.1 - 1.9e-05 24.9 11.4 1.9e-05 24.9 11.4 3.5 1 1 3 4 4 4 2 Fibrinogen alpha/beta chain family DUF1664 PF07889.12 EGC29127.1 - 2.2e-05 24.5 18.3 0.0012 18.9 2.9 3.3 1 1 3 4 4 4 2 Protein of unknown function (DUF1664) Baculo_PEP_C PF04513.12 EGC29127.1 - 0.0001 22.4 17.3 0.028 14.4 6.6 2.9 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.12 EGC29127.1 - 0.00023 21.2 23.8 0.0022 18.0 9.1 2.7 1 1 1 2 2 2 1 Laminin Domain II Spc7 PF08317.11 EGC29127.1 - 0.00028 19.9 32.0 0.0052 15.7 11.1 2.7 1 1 1 2 2 2 1 Spc7 kinetochore protein GAS PF13851.6 EGC29127.1 - 0.00045 19.6 34.4 0.094 12.1 25.0 3.1 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding MscS_porin PF12795.7 EGC29127.1 - 0.00075 19.1 24.0 0.0014 18.2 23.1 1.9 1 1 1 2 2 2 1 Mechanosensitive ion channel porin domain ADIP PF11559.8 EGC29127.1 - 0.001 19.2 26.7 0.0081 16.3 7.9 3.0 2 1 1 3 3 3 2 Afadin- and alpha -actinin-Binding AAA_13 PF13166.6 EGC29127.1 - 0.0014 17.4 29.9 0.0034 16.1 10.9 2.1 1 1 1 2 2 2 2 AAA domain DUF948 PF06103.11 EGC29127.1 - 0.0014 18.8 8.8 0.57 10.5 0.1 3.7 1 1 2 3 3 3 2 Bacterial protein of unknown function (DUF948) LOH1CR12 PF10158.9 EGC29127.1 - 0.0017 18.3 13.7 0.047 13.7 2.9 2.6 1 1 1 2 2 2 2 Tumour suppressor protein THOC7 PF05615.13 EGC29127.1 - 0.0029 17.9 22.3 0.01 16.1 11.3 3.0 1 1 1 3 3 2 1 Tho complex subunit 7 BAR_3 PF16746.5 EGC29127.1 - 0.003 17.3 14.8 0.003 17.3 14.8 1.9 2 0 0 2 2 2 1 BAR domain of APPL family TMF_DNA_bd PF12329.8 EGC29127.1 - 0.0039 17.1 8.6 0.0039 17.1 8.6 4.4 2 2 2 4 4 4 1 TATA element modulatory factor 1 DNA binding DivIVA PF05103.13 EGC29127.1 - 0.0042 17.2 2.2 0.0042 17.2 2.2 3.5 3 1 0 3 3 3 1 DivIVA protein DUF713 PF05218.14 EGC29127.1 - 0.0053 16.5 7.1 0.0053 16.5 7.1 3.0 2 1 1 3 3 3 1 Protein of unknown function (DUF713) DUF4407 PF14362.6 EGC29127.1 - 0.0068 15.8 9.7 0.0068 15.8 9.7 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4407) APG6_N PF17675.1 EGC29127.1 - 0.0071 16.9 29.2 0.066 13.7 10.8 3.0 1 1 2 3 3 3 2 Apg6 coiled-coil region Lebercilin PF15619.6 EGC29127.1 - 0.016 14.9 28.5 0.02 14.5 7.8 3.2 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease T3SSipB PF16535.5 EGC29127.1 - 0.022 15.2 6.3 0.022 15.2 6.3 2.6 1 1 1 2 2 2 0 Type III cell invasion protein SipB Golgin_A5 PF09787.9 EGC29127.1 - 0.023 14.1 28.1 0.0088 15.5 24.3 1.8 1 1 1 2 2 2 0 Golgin subfamily A member 5 SlyX PF04102.12 EGC29127.1 - 0.024 15.2 16.1 1.5 9.5 0.8 4.0 2 1 2 4 4 3 0 SlyX Syntaxin_2 PF14523.6 EGC29127.1 - 0.025 14.9 8.7 0.025 14.9 8.7 4.1 1 1 3 4 4 4 0 Syntaxin-like protein NPV_P10 PF05531.12 EGC29127.1 - 0.025 15.0 23.9 0.61 10.6 2.6 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein DASH_Duo1 PF08651.10 EGC29127.1 - 0.026 14.3 15.1 0.9 9.4 0.9 4.3 2 1 3 5 5 4 0 DASH complex subunit Duo1 TMF_TATA_bd PF12325.8 EGC29127.1 - 0.028 14.7 8.5 0.028 14.7 8.5 3.6 1 1 2 3 3 2 0 TATA element modulatory factor 1 TATA binding TMPIT PF07851.13 EGC29127.1 - 0.028 13.7 22.5 0.057 12.7 9.0 2.6 1 1 1 2 2 2 0 TMPIT-like protein LPP PF04728.13 EGC29127.1 - 0.032 14.6 18.6 0.18 12.2 0.5 4.4 3 1 0 3 3 3 0 Lipoprotein leucine-zipper FH2 PF02181.23 EGC29127.1 - 0.033 13.3 16.8 0.07 12.2 7.3 2.7 1 1 2 3 3 3 0 Formin Homology 2 Domain PI3K_P85_iSH2 PF16454.5 EGC29127.1 - 0.033 13.8 29.4 0.62 9.6 26.4 2.6 1 1 1 2 2 2 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain DUF4349 PF14257.6 EGC29127.1 - 0.039 13.4 10.1 0.97 8.8 3.2 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) CLZ PF16526.5 EGC29127.1 - 0.041 14.2 0.5 0.041 14.2 0.5 4.1 3 1 2 5 5 3 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels DUF4201 PF13870.6 EGC29127.1 - 0.043 13.5 34.8 0.029 14.1 17.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) DUF3450 PF11932.8 EGC29127.1 - 0.045 13.1 27.7 0.27 10.5 10.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) ERM PF00769.19 EGC29127.1 - 0.045 13.6 24.1 0.34 10.7 5.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.9 EGC29127.1 - 0.059 13.4 27.8 6 6.9 9.4 3.9 1 1 2 4 4 4 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Prominin PF05478.11 EGC29127.1 - 0.071 11.1 21.6 0.021 12.8 14.7 2.0 1 1 1 2 2 2 0 Prominin Prefoldin PF02996.17 EGC29127.1 - 0.085 12.8 27.8 0.12 12.3 2.9 4.8 2 2 2 4 4 4 0 Prefoldin subunit PspA_IM30 PF04012.12 EGC29127.1 - 0.097 12.2 16.7 0.038 13.6 11.7 2.8 1 1 1 2 2 2 0 PspA/IM30 family FUSC PF04632.12 EGC29127.1 - 0.1 11.1 0.1 0.13 10.7 0.1 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family HsbA PF12296.8 EGC29127.1 - 0.11 13.0 7.8 1.2 9.6 1.0 2.8 1 1 0 2 2 2 0 Hydrophobic surface binding protein A WEMBL PF05701.11 EGC29127.1 - 0.12 11.1 22.0 0.15 10.7 10.1 2.2 1 1 1 2 2 2 0 Weak chloroplast movement under blue light DUF4315 PF14193.6 EGC29127.1 - 0.12 12.4 0.6 0.12 12.4 0.6 4.2 2 1 1 5 5 3 0 Domain of unknown function (DUF4315) SUKH-4 PF14435.6 EGC29127.1 - 0.12 12.4 0.1 0.18 11.9 0.1 1.3 1 0 0 1 1 1 0 SUKH-4 immunity protein Barttin PF15462.6 EGC29127.1 - 0.13 12.1 2.1 1.2 8.9 0.0 2.2 1 1 1 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) DUF2443 PF10398.9 EGC29127.1 - 0.14 12.3 0.4 0.14 12.3 0.4 4.2 4 2 0 4 4 3 0 Protein of unknown function (DUF2443) ATG16 PF08614.11 EGC29127.1 - 0.15 12.3 22.0 0.22 11.7 10.0 2.5 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) UPF0242 PF06785.11 EGC29127.1 - 0.17 12.0 36.0 1.4 8.9 12.9 2.4 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus TPR_MLP1_2 PF07926.12 EGC29127.1 - 0.17 11.9 26.5 0.6 10.2 16.9 3.4 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein HrpB7 PF09486.10 EGC29127.1 - 0.17 12.2 7.1 0.72 10.2 3.3 2.7 1 1 1 3 3 3 0 Bacterial type III secretion protein (HrpB7) COG2 PF06148.11 EGC29127.1 - 0.19 11.8 14.8 1.2 9.3 0.3 3.6 2 1 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 MCPsignal PF00015.21 EGC29127.1 - 0.2 11.5 12.7 1.5 8.6 5.0 2.9 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Sec34 PF04136.15 EGC29127.1 - 0.2 11.5 18.7 1.3 8.9 4.6 3.0 1 1 1 2 2 2 0 Sec34-like family EzrA PF06160.12 EGC29127.1 - 0.25 9.5 34.2 1.5 6.9 34.2 2.1 1 1 0 1 1 1 0 Septation ring formation regulator, EzrA Exonuc_VII_L PF02601.15 EGC29127.1 - 0.27 10.8 21.1 0.023 14.3 6.6 2.1 1 1 1 2 2 2 0 Exonuclease VII, large subunit DUF2203 PF09969.9 EGC29127.1 - 0.28 11.9 16.8 0.79 10.5 5.6 3.2 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) TACC_C PF05010.14 EGC29127.1 - 0.33 10.7 28.2 1.1 9.1 9.8 3.2 1 1 2 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF4140 PF13600.6 EGC29127.1 - 0.33 11.4 18.7 4.2 7.9 2.9 4.0 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF2935 PF11155.8 EGC29127.1 - 0.34 11.3 7.7 4.5 7.6 0.1 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) DUF724 PF05266.14 EGC29127.1 - 0.34 10.7 27.2 0.022 14.6 9.0 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) DUF2703 PF10865.8 EGC29127.1 - 0.36 11.0 3.0 0.51 10.5 0.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF2703) HIP1_clath_bdg PF16515.5 EGC29127.1 - 0.38 11.4 23.2 0.86 10.3 3.4 3.7 1 1 2 4 4 4 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CALCOCO1 PF07888.11 EGC29127.1 - 0.39 9.5 25.9 0.12 11.2 14.4 2.3 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF3452 PF11934.8 EGC29127.1 - 0.46 10.1 6.3 0.39 10.3 2.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF3452) Cep57_CLD_2 PF14197.6 EGC29127.1 - 0.48 10.6 16.6 0.17 12.0 3.7 3.6 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 FmiP_Thoc5 PF09766.9 EGC29127.1 - 0.52 9.5 23.6 0.015 14.6 7.4 3.0 1 1 1 3 3 3 0 Fms-interacting protein/Thoc5 Prefoldin_2 PF01920.20 EGC29127.1 - 0.54 10.2 32.8 2 8.4 4.5 5.2 2 2 0 3 3 3 0 Prefoldin subunit DHR10 PF18595.1 EGC29127.1 - 0.69 10.0 24.9 0.62 10.1 3.1 3.4 1 1 2 3 3 3 0 Designed helical repeat protein 10 domain KxDL PF10241.9 EGC29127.1 - 0.75 10.1 0.1 0.75 10.1 0.1 4.7 1 1 4 5 5 5 0 Uncharacterized conserved protein Filament PF00038.21 EGC29127.1 - 0.8 9.2 30.0 0.46 10.0 11.4 3.1 1 1 1 3 3 2 0 Intermediate filament protein Ran-binding PF05508.11 EGC29127.1 - 0.83 8.6 27.0 0.69 8.8 12.4 3.3 1 1 2 3 3 3 0 RanGTP-binding protein DUF4200 PF13863.6 EGC29127.1 - 0.84 10.0 34.5 0.065 13.6 14.5 4.2 1 1 1 3 3 2 0 Domain of unknown function (DUF4200) DUF4527 PF15030.6 EGC29127.1 - 0.85 9.0 7.2 0.09 12.2 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4527) DUF4795 PF16043.5 EGC29127.1 - 0.88 9.1 30.3 73 2.9 29.5 3.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 EGC29127.1 - 0.92 10.0 21.7 0.12 12.9 7.9 3.7 1 1 2 4 4 4 0 Spectrin repeat Nup54 PF13874.6 EGC29127.1 - 0.96 9.5 15.8 0.75 9.9 3.7 3.2 2 1 0 3 3 3 0 Nucleoporin complex subunit 54 LUC7 PF03194.15 EGC29127.1 - 0.99 9.0 24.9 0.15 11.7 14.4 2.8 1 1 2 3 3 3 0 LUC7 N_terminus MAD PF05557.13 EGC29127.1 - 1.1 7.6 32.0 0.095 11.0 21.9 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein Tropomyosin PF00261.20 EGC29127.1 - 1.3 8.3 29.3 0.1 12.0 7.0 3.2 2 2 1 3 3 3 0 Tropomyosin Syntaxin-6_N PF09177.11 EGC29127.1 - 1.3 9.6 19.7 0.16 12.5 3.8 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF4164 PF13747.6 EGC29127.1 - 1.4 9.3 19.1 0.091 13.1 6.0 3.3 1 1 1 3 3 2 0 Domain of unknown function (DUF4164) FliJ PF02050.16 EGC29127.1 - 1.5 9.0 24.0 2.5 8.3 11.3 3.9 2 2 2 4 4 4 0 Flagellar FliJ protein MtrB PF05440.12 EGC29127.1 - 1.6 9.2 3.9 3.5 8.1 0.1 3.0 2 1 1 4 4 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Cluap1 PF10234.9 EGC29127.1 - 1.8 7.9 26.7 0.29 10.5 3.0 3.7 1 1 1 3 3 3 0 Clusterin-associated protein-1 Occludin_ELL PF07303.13 EGC29127.1 - 1.9 9.3 20.8 1.6 9.5 6.5 4.1 1 1 2 4 4 4 0 Occludin homology domain V_ATPase_I PF01496.19 EGC29127.1 - 1.9 6.3 19.2 5.9 4.7 19.2 1.8 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 EGC29127.1 - 1.9 8.9 23.5 1e+02 3.3 23.5 2.3 1 1 0 1 1 1 0 Fez1 SKA1 PF07160.12 EGC29127.1 - 2 8.2 23.6 1.9 8.3 8.4 2.9 1 1 1 2 2 2 0 Spindle and kinetochore-associated protein 1 APG17 PF04108.12 EGC29127.1 - 2 7.4 24.6 0.18 10.9 8.1 2.4 1 1 1 2 2 2 0 Autophagy protein Apg17 HMMR_N PF15905.5 EGC29127.1 - 2.1 7.7 32.3 3.6 7.0 29.3 2.3 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal FapA PF03961.13 EGC29127.1 - 2.4 6.7 31.3 0.065 11.8 10.7 2.9 1 1 2 3 3 3 0 Flagellar Assembly Protein A Atg14 PF10186.9 EGC29127.1 - 2.4 7.1 26.3 8.4 5.4 10.2 2.6 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 SOGA PF11365.8 EGC29127.1 - 2.5 9.3 16.6 0.58 11.3 5.5 3.1 2 2 0 2 2 2 0 Protein SOGA PDCD7 PF16021.5 EGC29127.1 - 2.6 7.1 18.1 0.029 13.5 6.1 2.2 1 1 1 2 2 2 0 Programmed cell death protein 7 CorA PF01544.18 EGC29127.1 - 2.7 7.3 23.4 0.04 13.2 7.8 2.7 1 1 2 3 3 3 0 CorA-like Mg2+ transporter protein DUF812 PF05667.11 EGC29127.1 - 2.7 6.8 31.0 0.3 9.9 13.3 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF812) OmpH PF03938.14 EGC29127.1 - 2.8 8.3 31.9 0.81 10.0 5.4 3.2 1 1 3 4 4 4 0 Outer membrane protein (OmpH-like) DASH_Spc19 PF08287.11 EGC29127.1 - 2.8 7.8 26.2 0.61 10.0 8.4 2.8 2 1 0 2 2 2 0 Spc19 MbeD_MobD PF04899.12 EGC29127.1 - 2.8 8.1 7.1 5 7.3 4.0 2.9 3 1 1 4 4 1 0 MbeD/MobD like Seryl_tRNA_N PF02403.22 EGC29127.1 - 2.9 8.2 34.1 4 7.7 12.0 3.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain CRR7 PF12095.8 EGC29127.1 - 2.9 8.4 9.3 35 4.9 0.0 4.1 2 1 3 5 5 5 0 Protein CHLORORESPIRATORY REDUCTION 7 HOOK PF05622.12 EGC29127.1 - 3.1 5.8 32.5 15 3.6 32.4 2.6 1 1 0 1 1 1 0 HOOK protein Phage_HK97_TLTM PF06120.11 EGC29127.1 - 3.2 6.9 29.4 0.26 10.4 9.9 2.2 1 1 1 2 2 2 0 Tail length tape measure protein COG5 PF10392.9 EGC29127.1 - 3.2 7.9 17.1 2.9 8.1 2.8 3.6 2 2 1 3 3 3 0 Golgi transport complex subunit 5 Fzo_mitofusin PF04799.13 EGC29127.1 - 3.4 7.2 17.8 0.8 9.2 5.7 3.4 1 1 3 4 4 4 0 fzo-like conserved region Med21 PF11221.8 EGC29127.1 - 3.4 7.9 19.3 0.055 13.7 8.5 2.7 2 1 0 3 3 2 0 Subunit 21 of Mediator complex Sulfatase_C PF14707.6 EGC29127.1 - 3.4 8.4 5.7 22 5.8 0.3 3.4 2 2 1 3 3 2 0 C-terminal region of aryl-sulfatase IFT57 PF10498.9 EGC29127.1 - 3.5 6.5 31.6 0.083 11.8 16.1 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Alpha-2-MRAP_C PF06401.11 EGC29127.1 - 4.2 7.3 26.8 0.36 10.7 9.8 2.9 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain Matrilin_ccoil PF10393.9 EGC29127.1 - 4.2 7.3 8.4 29 4.6 0.1 4.2 3 1 1 4 4 3 0 Trimeric coiled-coil oligomerisation domain of matrilin DUF1465 PF07323.12 EGC29127.1 - 4.5 7.1 8.0 1.1 9.1 1.0 2.6 1 1 3 4 4 3 0 Protein of unknown function (DUF1465) FlaC_arch PF05377.11 EGC29127.1 - 4.8 7.6 26.8 6.6 7.2 1.4 5.6 2 2 3 5 5 5 0 Flagella accessory protein C (FlaC) Snapin_Pallidin PF14712.6 EGC29127.1 - 5 7.6 25.4 1.9 8.9 4.8 4.2 1 1 2 3 3 3 0 Snapin/Pallidin DUF4298 PF14131.6 EGC29127.1 - 5.4 7.1 17.5 1.1 9.2 0.5 4.0 4 0 0 4 4 3 0 Domain of unknown function (DUF4298) DivIC PF04977.15 EGC29127.1 - 5.6 6.8 35.0 0.38 10.6 2.7 5.2 2 2 3 5 5 5 0 Septum formation initiator HemX PF04375.14 EGC29127.1 - 7.1 5.8 22.2 91 2.2 5.5 2.9 1 1 1 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cep57_MT_bd PF06657.13 EGC29127.1 - 7.2 7.1 20.3 1.2 9.7 1.0 4.1 2 2 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 YscO-like PF16789.5 EGC29127.1 - 7.3 6.6 24.5 0.31 11.0 5.4 3.0 1 1 2 3 3 2 0 YscO-like protein YabA PF06156.13 EGC29127.1 - 7.3 7.3 25.3 3.1 8.5 3.6 4.1 1 1 1 3 3 3 0 Initiation control protein YabA DUF4239 PF14023.6 EGC29127.1 - 7.4 6.2 7.5 2.7 7.6 0.9 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4239) Glu-tRNAGln PF02686.15 EGC29127.1 - 9.5 6.6 7.9 18 5.7 2.5 3.4 2 1 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit HMMR_N PF15905.5 EGC29128.1 - 0.054 13.0 0.1 0.086 12.3 0.1 1.2 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Mo-nitro_C PF06967.11 EGC29128.1 - 0.26 11.3 2.0 2.1 8.4 0.1 2.7 3 0 0 3 3 3 0 Mo-dependent nitrogenase C-terminus DUF3199 PF11436.8 EGC29128.1 - 0.68 10.0 3.4 0.91 9.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3199) Sacchrp_dh_C PF16653.5 EGC29130.1 - 1.4e-72 245.0 0.0 1e-71 242.2 0.0 2.1 2 0 0 2 2 2 1 Saccharopine dehydrogenase C-terminal domain AlaDh_PNT_N PF05222.15 EGC29130.1 - 1.2e-27 96.8 0.0 2.6e-27 95.8 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain Sacchrp_dh_NADP PF03435.18 EGC29130.1 - 2.7e-21 76.2 0.1 5.3e-21 75.2 0.1 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain AlaDh_PNT_C PF01262.21 EGC29130.1 - 2.3e-08 33.6 0.0 1.7e-05 24.2 0.0 2.8 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGC29130.1 - 0.00045 20.5 0.1 0.001 19.3 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGC29130.1 - 0.064 13.3 0.0 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase His_Phos_2 PF00328.22 EGC29131.1 - 1.3e-20 74.1 1.3 7.9e-20 71.5 1.3 2.0 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OTU PF02338.19 EGC29132.1 - 1.2e-12 48.4 0.0 1.2e-12 48.4 0.0 3.1 2 1 0 2 2 2 1 OTU-like cysteine protease Nbs1_C PF08599.10 EGC29132.1 - 0.039 14.1 0.1 0.039 14.1 0.1 3.8 3 0 0 3 3 3 0 DNA damage repair protein Nbs1 AAA_11 PF13086.6 EGC29132.1 - 0.84 9.4 27.2 0.23 11.2 1.5 2.8 3 0 0 3 3 3 0 AAA domain Macoilin PF09726.9 EGC29134.1 - 3.8 6.0 7.8 4.1 5.9 7.8 1.0 1 0 0 1 1 1 0 Macoilin family Glyco_hydro_101 PF12905.7 EGC29135.1 - 0.016 14.6 0.4 0.12 11.7 0.1 1.9 2 0 0 2 2 2 0 Endo-alpha-N-acetylgalactosaminidase TPR_1 PF00515.28 EGC29139.1 - 4.5e-15 54.7 7.9 7.1e-07 28.8 0.3 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC29139.1 - 4.1e-12 45.2 5.8 1.5e-05 24.7 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC29139.1 - 3.3e-10 39.5 12.0 7.1e-07 28.8 4.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_8 PF13181.6 EGC29139.1 - 1.2e-08 34.5 5.2 0.0037 17.3 0.2 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC29139.1 - 2.3e-07 31.0 1.8 3.7e-06 27.1 0.5 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC29139.1 - 1.6e-06 27.7 0.3 0.033 14.2 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC29139.1 - 6.4e-06 26.7 0.1 1.4e-05 25.7 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC29139.1 - 1.7e-05 25.2 0.0 0.058 14.2 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC29139.1 - 2e-05 25.0 0.5 5.8e-05 23.5 0.5 1.9 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC29139.1 - 0.00018 21.7 6.2 0.0034 17.6 0.8 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC29139.1 - 0.0002 21.5 1.0 0.0015 18.7 1.1 2.4 3 0 0 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGC29139.1 - 0.0026 17.9 0.0 0.0051 16.9 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 EGC29139.1 - 0.0087 16.1 0.6 0.0087 16.1 0.6 3.3 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_10 PF13374.6 EGC29139.1 - 0.016 15.1 2.5 2.7 8.0 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGC29139.1 - 0.023 14.1 0.4 0.75 9.3 0.1 2.5 2 0 0 2 2 2 0 SHNi-TPR PPR PF01535.20 EGC29139.1 - 0.12 12.7 0.6 1 9.7 0.1 2.5 2 0 0 2 2 2 0 PPR repeat ELYS PF13934.6 EGC29140.1 - 2e-20 73.8 0.9 2e-20 73.8 0.9 1.8 2 0 0 2 2 2 1 Nuclear pore complex assembly Membrane_bind PF14564.6 EGC29141.1 - 1.3e-33 115.7 0.6 1.5e-33 115.5 0.6 1.0 1 0 0 1 1 1 1 Membrane binding Big_8 PF17961.1 EGC29141.1 - 0.086 13.0 1.2 2.7 8.2 0.1 2.8 1 1 1 2 2 2 0 Bacterial Ig domain PSI PF01437.25 EGC29142.1 - 0.00021 21.8 11.8 0.00021 21.8 11.8 1.8 2 0 0 2 2 1 1 Plexin repeat EphA2_TM PF14575.6 EGC29142.1 - 0.00092 20.0 0.0 0.058 14.3 0.0 2.2 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain LYRIC PF15686.5 EGC29142.1 - 0.0016 18.1 0.2 0.0025 17.4 0.0 1.3 2 0 0 2 2 2 1 Lysine-rich CEACAM1 co-isolated protein family Baculo_11_kDa PF06143.11 EGC29142.1 - 0.0019 17.7 0.3 0.45 10.1 0.1 2.3 2 0 0 2 2 2 2 Baculovirus 11 kDa family Shisa PF13908.6 EGC29142.1 - 0.0023 18.2 5.4 0.0023 18.2 5.4 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator DUF4006 PF13179.6 EGC29142.1 - 0.01 15.7 0.0 6.3 6.8 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF4006) TMEM154 PF15102.6 EGC29142.1 - 0.027 14.4 0.2 0.8 9.6 0.0 2.3 2 0 0 2 2 2 0 TMEM154 protein family DUF4972 PF16342.5 EGC29142.1 - 0.03 14.0 0.4 0.36 10.5 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4972) Cadherin_C_2 PF16492.5 EGC29142.1 - 0.035 14.9 0.2 4.4 8.1 0.0 2.3 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Protocadherin PF08374.11 EGC29142.1 - 0.068 13.1 1.6 0.097 12.6 0.0 1.9 2 1 0 2 2 2 0 Protocadherin Comm PF15957.5 EGC29142.1 - 0.14 12.5 0.2 0.14 12.5 0.2 1.7 2 1 0 2 2 2 0 Commissureless MLANA PF14991.6 EGC29142.1 - 0.15 12.4 0.2 0.26 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein melan-A Prominin PF05478.11 EGC29142.1 - 1.6 6.6 6.8 2.3 6.0 6.8 1.2 1 0 0 1 1 1 0 Prominin Orthoreo_P10 PF07204.11 EGC29142.1 - 4.5 7.3 9.8 1.2 9.1 6.6 1.9 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 GATA PF00320.27 EGC29143.1 - 1.2e-14 53.6 4.5 2.4e-14 52.6 4.5 1.5 1 0 0 1 1 1 1 GATA zinc finger Androgen_recep PF02166.16 EGC29143.1 - 0.38 9.5 16.7 0.62 8.8 16.7 1.2 1 0 0 1 1 1 0 Androgen receptor RED_N PF07808.13 EGC29143.1 - 0.47 10.0 15.2 1.3 8.6 15.2 1.6 1 0 0 1 1 1 0 RED-like protein N-terminal region zinc_ribbon_9 PF14369.6 EGC29143.1 - 1.3 9.3 3.1 2.9 8.2 3.1 1.5 1 0 0 1 1 1 0 zinc-ribbon TFIIA PF03153.13 EGC29143.1 - 2.3 8.1 41.1 0.02 14.9 30.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF4407 PF14362.6 EGC29143.1 - 7 5.9 11.1 10 5.4 11.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Mucin PF01456.17 EGC29143.1 - 7.1 6.6 14.9 1.4 8.9 8.5 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Utp14 PF04615.13 EGC29143.1 - 8.4 4.8 16.1 12 4.3 16.1 1.2 1 0 0 1 1 1 0 Utp14 protein Rad60-SLD PF11976.8 EGC29144.1 - 9.2e-05 22.2 2.0 0.00049 19.9 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Hid1 PF12722.7 EGC29146.1 - 2.3 6.3 17.6 3.8 5.5 17.6 1.4 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nop14 PF04147.12 EGC29146.1 - 7.5 4.6 49.5 0.48 8.6 44.4 1.6 2 0 0 2 2 2 0 Nop14-like family COX7C PF02935.16 EGC29149.1 - 0.00013 22.1 2.6 0.0073 16.5 0.1 2.1 2 0 0 2 2 2 2 Cytochrome c oxidase subunit VIIc Fe-ADH PF00465.19 EGC29151.1 - 1.1e-57 195.6 0.0 1.2e-57 195.4 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.6 EGC29151.1 - 2.6e-30 105.9 0.0 3.4e-30 105.5 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.20 EGC29151.1 - 1e-05 24.9 0.3 0.00042 19.5 0.2 3.1 1 1 1 2 2 2 1 3-dehydroquinate synthase KDGP_aldolase PF07071.11 EGC29151.1 - 0.0018 18.1 0.1 2.3 8.0 0.0 2.3 2 0 0 2 2 2 2 KDGP aldolase PFK PF00365.20 EGC29151.1 - 0.048 13.0 0.0 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphofructokinase TINF2_N PF14973.6 EGC29151.1 - 0.052 13.9 0.6 0.27 11.6 0.0 2.1 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Sugar-bind PF04198.13 EGC29151.1 - 0.066 12.3 0.0 10 5.1 0.0 2.3 2 0 0 2 2 2 0 Putative sugar-binding domain tRNA-synt_1c PF00749.21 EGC29152.1 - 7.2e-110 366.8 0.0 1.1e-109 366.1 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain UPF0253 PF06786.12 EGC29152.1 - 0.097 13.0 0.1 0.51 10.6 0.0 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) EF-G-binding_N PF07299.11 EGC29152.1 - 0.23 12.0 3.8 0.37 11.4 0.1 3.0 2 1 2 4 4 4 0 Elongation factor G-binding protein, N-terminal Chlamy_scaf PF09675.10 EGC29153.1 - 0.018 15.4 0.5 0.031 14.6 0.5 1.4 1 0 0 1 1 1 0 Chlamydia-phage Chp2 scaffold (Chlamy_scaf) CDC45 PF02724.14 EGC29153.1 - 2 6.6 13.1 2.2 6.4 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein UQ_con PF00179.26 EGC29154.1 - 9.9e-52 174.3 0.2 1.1e-51 174.1 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC29154.1 - 0.098 13.0 0.9 0.13 12.5 0.9 1.5 1 1 0 1 1 1 0 RWD domain Rrp15p PF07890.12 EGC29155.1 - 8.3e-17 61.8 11.5 8.3e-17 61.8 11.5 2.2 2 1 0 2 2 2 1 Rrp15p Med15 PF09606.10 EGC29155.1 - 0.00055 18.8 0.7 0.00064 18.6 0.7 1.0 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DKCLD PF08068.12 EGC29155.1 - 0.078 13.1 0.1 0.35 11.0 0.0 2.0 1 1 1 2 2 2 0 DKCLD (NUC011) domain DUF4724 PF15852.5 EGC29155.1 - 0.27 11.7 10.2 0.28 11.7 1.5 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4724) SUFU_C PF12470.8 EGC29155.1 - 2.1 8.3 10.2 0.77 9.8 7.6 1.7 1 1 1 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain Peptidase_C14 PF00656.22 EGC29156.1 - 0.0048 16.9 0.0 0.0055 16.7 0.0 1.3 1 0 0 1 1 1 1 Caspase domain HTH_Tnp_4 PF13613.6 EGC29157.1 - 0.16 11.7 0.0 0.31 10.8 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Phosphorylase PF00343.20 EGC29158.1 - 0 1050.2 0.1 0 1050.0 0.1 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Sod_Cu PF00080.20 EGC29159.1 - 1.6e-46 158.0 7.8 2e-46 157.7 7.8 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HemeBinding_Shp PF11545.8 EGC29159.1 - 0.055 13.5 0.1 0.092 12.7 0.1 1.3 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp Nucleoside_tran PF01733.18 EGC29160.1 - 1.5e-29 103.4 13.0 1.5e-29 103.4 13.0 1.8 1 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.16 EGC29160.1 - 8.8e-08 31.5 24.2 2e-07 30.3 4.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily OAD_gamma PF04277.13 EGC29160.1 - 0.13 12.9 0.0 0.13 12.9 0.0 3.4 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Orai-1 PF07856.12 EGC29160.1 - 3.6 7.2 12.2 0.51 10.0 0.9 2.7 2 2 0 2 2 2 0 Mediator of CRAC channel activity Nucleoside_tran PF01733.18 EGC29161.1 - 2.3e-34 119.2 17.0 2.3e-34 119.2 17.0 2.3 2 0 0 2 2 2 1 Nucleoside transporter Phage_holin_2_1 PF04971.12 EGC29161.1 - 0.057 13.4 0.1 1.2 9.2 0.0 2.8 2 0 0 2 2 2 0 Bacteriophage P21 holin S DUF1440 PF07274.12 EGC29161.1 - 0.2 12.0 8.1 0.046 14.1 3.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1440) Sec34 PF04136.15 EGC29162.1 - 2.6e-30 105.2 5.5 2.6e-30 105.2 5.5 3.0 2 2 0 2 2 2 1 Sec34-like family Sod_Cu PF00080.20 EGC29163.1 - 2.1e-26 92.8 0.1 2.6e-26 92.5 0.1 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Piezo_RRas_bdg PF12166.8 EGC29164.1 - 2.7e-99 333.4 2.2 2.7e-99 333.4 2.2 4.2 5 0 0 5 5 5 1 Piezo non-specific cation channel, R-Ras-binding domain PHD PF00628.29 EGC29166.1 - 1.3e-10 40.9 5.8 3.2e-10 39.7 5.8 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.6 EGC29166.1 - 0.0009 19.4 1.6 0.0009 19.4 1.6 2.9 3 0 0 3 3 3 1 PHD-like zinc-binding domain zf-RING-like PF08746.11 EGC29166.1 - 0.13 12.6 1.2 0.34 11.2 1.2 1.7 1 0 0 1 1 1 0 RING-like domain FANCL_C PF11793.8 EGC29166.1 - 0.29 11.4 3.4 0.95 9.7 3.4 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain PHD_2 PF13831.6 EGC29166.1 - 0.96 9.1 7.6 0.048 13.2 1.8 1.9 2 0 0 2 2 2 0 PHD-finger Homeodomain PF00046.29 EGC29167.1 - 2.4e-19 68.9 4.4 4.7e-19 68.0 4.4 1.5 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGC29167.1 - 0.0038 17.1 0.2 0.016 15.1 0.2 2.1 1 0 0 1 1 1 1 Homeobox KN domain p53-inducible11 PF14936.6 EGC29167.1 - 0.13 12.3 0.3 0.21 11.6 0.3 1.2 1 0 0 1 1 1 0 Tumour protein p53-inducible protein 11 COMM_domain PF07258.14 EGC29168.1 - 3.5e-20 71.9 0.3 7e-20 70.9 0.3 1.4 1 0 0 1 1 1 1 COMM domain DUF3216 PF11505.8 EGC29168.1 - 0.088 13.0 0.1 0.21 11.8 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) GA PF01468.17 EGC29168.1 - 1.1 9.6 3.5 3 8.2 0.2 3.1 3 1 1 4 4 4 0 GA module Dicty_REP PF05086.12 EGC29169.1 - 0.68 7.8 21.3 0.88 7.5 14.7 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein TFIIA PF03153.13 EGC29169.1 - 4.9 7.0 30.8 0.14 12.1 11.7 2.6 2 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit RrnaAD PF00398.20 EGC29171.1 - 2e-63 213.9 0.0 2.5e-63 213.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGC29171.1 - 1.3e-08 35.4 0.0 3e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC29171.1 - 6.4e-06 26.7 0.0 1.4e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29171.1 - 2.2e-05 25.1 0.0 5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGC29171.1 - 6e-05 22.5 0.0 0.0001 21.7 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PCMT PF01135.19 EGC29171.1 - 0.00024 20.9 0.0 0.00035 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EGC29171.1 - 0.00059 19.5 0.0 0.0011 18.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_23 PF13489.6 EGC29171.1 - 0.00088 19.1 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EGC29171.1 - 0.0055 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_31 PF13847.6 EGC29171.1 - 0.0066 16.2 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC29171.1 - 0.0069 16.3 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC29171.1 - 0.0095 15.5 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGC29171.1 - 0.011 15.1 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DOT1 PF08123.13 EGC29171.1 - 0.014 15.0 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_4 PF02390.17 EGC29171.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_2 PF00891.18 EGC29171.1 - 0.02 14.2 0.0 0.034 13.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase domain Zn_ribbon_2 PF12674.7 EGC29171.1 - 0.042 14.5 0.1 0.099 13.3 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain PRMT5 PF05185.16 EGC29171.1 - 0.05 13.5 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 PRMT5 arginine-N-methyltransferase tRNA_U5-meth_tr PF05958.11 EGC29171.1 - 0.078 12.0 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_28 PF02636.17 EGC29171.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 EGC29171.1 - 0.11 12.5 0.0 0.2 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.13 EGC29171.1 - 0.15 11.4 0.0 0.22 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Stork_head PF10264.9 EGC29172.1 - 0.011 15.8 0.2 2.2 8.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix Storkhead-box1 domain MFS_1 PF07690.16 EGC29173.1 - 3.9e-51 174.1 44.0 2.2e-49 168.3 47.1 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.13 EGC29173.1 - 4.6e-23 81.5 30.6 6.6e-23 81.0 30.6 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.24 EGC29173.1 - 6.4e-15 54.9 6.2 6.4e-15 54.9 6.2 2.9 3 0 0 3 3 3 2 Sugar (and other) transporter DUF2547 PF10818.8 EGC29174.1 - 3.7 8.5 9.0 5.2 8.1 6.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2547) Robl_LC7 PF03259.17 EGC29176.1 - 3.2e-07 30.0 0.0 3.3e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGC29176.1 - 0.00036 20.4 0.0 0.00042 20.2 0.0 1.1 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 WASH-7_N PF14745.6 EGC29177.1 - 7.3e-200 665.3 17.3 7.3e-200 665.3 17.3 1.9 2 0 0 2 2 2 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.6 EGC29177.1 - 7.1e-149 495.6 8.4 7.1e-149 495.6 8.4 2.6 4 0 0 4 4 4 1 WASH complex subunit 7 WASH-7_C PF14746.6 EGC29177.1 - 6.4e-61 205.1 5.8 2.5e-60 203.1 5.8 2.1 1 0 0 1 1 1 1 WASH complex subunit 7, C-terminal Mating_N PF12731.7 EGC29177.1 - 0.03 14.4 0.6 0.11 12.6 0.1 2.2 2 0 0 2 2 2 0 Mating-type protein beta 1 TetR_C_27 PF17935.1 EGC29177.1 - 0.089 12.9 0.1 0.64 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain PCI PF01399.27 EGC29179.1 - 6.8e-21 74.8 2.6 8.8e-21 74.4 0.3 2.2 2 1 0 2 2 2 1 PCI domain RPN5_C PF18098.1 EGC29179.1 - 1e-15 57.5 1.3 2.5e-15 56.3 1.3 1.7 1 0 0 1 1 1 1 26S proteasome regulatory subunit RPN5 C-terminal domain CSN8_PSD8_EIF3K PF10075.9 EGC29179.1 - 0.021 14.8 0.0 0.055 13.5 0.0 1.7 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family Pkinase PF00069.25 EGC29180.1 - 6.3e-77 258.5 0.0 6.3e-77 258.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29180.1 - 5.4e-45 153.7 0.0 1.5e-44 152.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGC29180.1 - 2e-18 65.9 0.1 3.7e-18 65.0 0.1 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EGC29180.1 - 3.9e-06 26.4 0.0 7.8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 Kinase-like UBA PF00627.31 EGC29180.1 - 3.1e-05 23.8 0.3 6.2e-05 22.8 0.3 1.5 1 0 0 1 1 1 1 UBA/TS-N domain RIO1 PF01163.22 EGC29180.1 - 9.7e-05 22.0 0.2 9.7e-05 22.0 0.2 2.3 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EGC29180.1 - 0.00071 19.0 0.1 0.0018 17.6 0.1 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC29180.1 - 0.0026 17.7 0.0 0.009 15.9 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family UBA_2 PF08587.11 EGC29180.1 - 0.097 12.8 0.5 0.39 10.9 0.0 2.3 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) UBA_3 PF09288.10 EGC29180.1 - 0.18 11.6 1.9 0.29 11.0 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Beta_helix PF13229.6 EGC29181.1 - 3.1e-33 114.9 54.8 2.9e-19 69.5 14.3 4.3 3 1 1 4 4 4 3 Right handed beta helix region NosD PF05048.13 EGC29181.1 - 1.3e-20 73.7 39.7 3.6e-13 49.4 24.1 4.3 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) F-box-like PF12937.7 EGC29181.1 - 5.1e-06 26.3 1.1 9.5e-06 25.4 1.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC29181.1 - 0.0023 17.8 0.8 0.005 16.7 0.8 1.5 1 0 0 1 1 1 1 F-box domain H_lectin PF09458.10 EGC29182.1 - 8e-21 74.0 0.2 2e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 H-type lectin domain F5_F8_type_C PF00754.25 EGC29182.1 - 1.1e-19 70.7 3.5 1.2e-19 70.7 1.2 2.0 2 1 0 2 2 2 1 F5/8 type C domain Adaptin_binding PF10199.9 EGC29183.1 - 0.028 15.0 2.9 0.028 15.0 2.9 1.9 2 0 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 Pro_sub2 PF18513.1 EGC29183.1 - 0.26 11.5 0.2 0.26 11.5 0.2 3.4 2 2 0 3 3 3 0 Prodomain subtilisin 2 RNR_Alpha PF17975.1 EGC29184.1 - 3.9e-44 149.3 1.1 1.2e-43 147.7 0.9 2.0 2 0 0 2 2 2 1 Ribonucleotide reductase alpha domain Ribonuc_red_lgC PF02867.15 EGC29184.1 - 5.2e-13 48.4 0.0 6.4e-05 21.7 0.0 3.4 2 1 1 3 3 3 3 Ribonucleotide reductase, barrel domain YonK PF09642.10 EGC29184.1 - 0.076 13.2 0.0 0.94 9.7 0.0 2.6 2 0 0 2 2 2 0 YonK protein ATP-grasp_3 PF02655.14 EGC29184.1 - 0.13 12.3 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain cwf18 PF08315.12 EGC29185.1 - 1e-15 58.6 19.3 1e-15 58.6 19.3 2.9 1 1 1 2 2 2 1 cwf18 pre-mRNA splicing factor SAP PF02037.27 EGC29185.1 - 7e-05 22.5 1.6 0.00017 21.3 1.6 1.6 1 0 0 1 1 1 1 SAP domain CAC1F_C PF16885.5 EGC29185.1 - 0.3 10.7 14.0 0.38 10.4 14.0 1.2 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term Dapper PF15268.6 EGC29185.1 - 0.42 9.4 20.0 0.43 9.4 20.0 1.1 1 0 0 1 1 1 0 Dapper CCSAP PF15748.5 EGC29185.1 - 0.54 10.4 18.3 0.95 9.6 18.3 1.5 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Presenilin PF01080.17 EGC29185.1 - 0.75 8.5 22.3 1.2 7.8 22.3 1.4 1 0 0 1 1 1 0 Presenilin HgmA PF04209.13 EGC29187.1 - 1.7e-219 728.8 0.0 1.9e-219 728.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase FlpD PF02662.16 EGC29188.1 - 0.13 12.3 0.1 0.18 11.8 0.1 1.2 1 0 0 1 1 1 0 Methyl-viologen-reducing hydrogenase, delta subunit Abhydrolase_3 PF07859.13 EGC29190.1 - 8.4e-64 215.3 1.8 1.3e-63 214.7 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold FYVE PF01363.21 EGC29190.1 - 5.4e-20 71.3 14.3 1.3e-19 70.1 11.7 2.5 2 0 0 2 2 2 1 FYVE zinc finger COesterase PF00135.28 EGC29190.1 - 2.6e-10 39.8 0.0 2.6e-10 39.8 0.0 2.6 2 1 0 2 2 2 1 Carboxylesterase family Say1_Mug180 PF10340.9 EGC29190.1 - 4.4e-06 25.8 0.5 1.3e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Steryl acetyl hydrolase XAP5 PF04921.14 EGC29190.1 - 0.00072 19.5 5.0 0.0011 18.8 5.0 1.2 1 0 0 1 1 1 1 XAP5, circadian clock regulator AXE1 PF05448.12 EGC29190.1 - 0.034 12.8 0.0 0.058 12.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Hydrolase_4 PF12146.8 EGC29190.1 - 0.035 13.4 0.0 0.067 12.4 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC29190.1 - 0.043 13.3 0.0 0.12 11.8 0.0 1.7 1 0 0 1 1 1 0 Prolyl oligopeptidase family Med3 PF11593.8 EGC29190.1 - 0.065 12.4 16.1 0.094 11.9 16.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF4746 PF15928.5 EGC29190.1 - 0.17 11.3 14.0 0.25 10.8 14.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Ndc1_Nup PF09531.10 EGC29190.1 - 0.25 10.0 5.1 0.31 9.7 5.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup eIF-3_zeta PF05091.12 EGC29190.1 - 0.39 9.6 10.8 0.55 9.2 10.8 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.22 EGC29190.1 - 0.77 8.9 6.3 1 8.5 6.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Esterase PF00756.20 EGC29190.1 - 1.6 8.3 6.2 12 5.5 0.0 2.8 3 0 0 3 3 3 0 Putative esterase CDC45 PF02724.14 EGC29190.1 - 1.6 6.9 11.4 2.2 6.5 11.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGC29190.1 - 2.9 6.5 15.7 4.4 6.0 15.7 1.2 1 0 0 1 1 1 0 Presenilin SpoIIP PF07454.11 EGC29190.1 - 3.5 7.0 13.7 5.9 6.3 13.7 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 EGC29190.1 - 3.8 6.2 13.4 5.9 5.6 13.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 zf-RING_5 PF14634.6 EGC29190.1 - 4 7.5 16.6 20 5.2 16.8 2.1 1 1 1 2 2 2 0 zinc-RING finger domain DUF4971 PF16341.5 EGC29190.1 - 6.3 6.6 6.0 1.1 9.1 0.1 2.3 3 0 0 3 3 2 0 Domain of unknown function (DUF4971) DUF913 PF06025.12 EGC29190.1 - 6.7 5.6 7.9 9.9 5.0 7.9 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Roughex PF06020.11 EGC29190.1 - 6.9 5.7 16.2 13 4.8 16.2 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Dicty_REP PF05086.12 EGC29190.1 - 7.1 4.5 15.6 10 3.9 15.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Borrelia_P83 PF05262.11 EGC29190.1 - 9.5 4.6 11.7 14 4.1 11.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.9 EGC29190.1 - 10 4.3 18.6 14 3.8 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FKBP_C PF00254.28 EGC29191.1 - 1.1e-25 89.7 0.2 1.5e-20 73.3 0.1 2.6 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_2 PF07719.17 EGC29191.1 - 8.7e-08 31.7 1.6 0.019 15.0 0.3 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC29191.1 - 3.2e-07 29.9 3.1 0.014 15.1 0.2 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.28 EGC29191.1 - 1.2e-06 28.1 4.0 0.024 14.5 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat FKBP_N_2 PF18023.1 EGC29191.1 - 5.4e-06 26.5 3.4 0.00095 19.2 0.6 3.5 4 0 0 4 4 4 2 BDBT FKBP like N-terminal TPR_8 PF13181.6 EGC29191.1 - 0.0052 16.9 5.9 0.57 10.5 0.2 3.0 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF4969 PF16339.5 EGC29191.1 - 0.054 13.8 1.1 0.22 11.9 1.1 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) TPR_17 PF13431.6 EGC29191.1 - 0.056 13.8 1.2 0.31 11.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC29191.1 - 0.15 12.3 0.2 8.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGC29191.1 - 0.17 12.0 0.0 0.34 11.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC29191.1 - 0.23 11.6 0.5 6.4 7.1 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TP53IP5 PF15331.6 EGC29191.1 - 0.37 10.9 4.2 0.97 9.5 4.2 1.7 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_2 PF13639.6 EGC29192.1 - 2.7e-06 27.6 16.6 5.7e-06 26.6 16.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC29192.1 - 7.9e-05 22.4 16.6 0.00015 21.5 16.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC29192.1 - 0.00063 19.5 14.0 0.001 18.8 14.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29192.1 - 0.0008 19.6 12.4 0.0022 18.2 12.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC29192.1 - 0.00086 19.1 18.0 0.0019 18.1 18.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29192.1 - 0.0084 16.1 9.5 0.025 14.6 9.5 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGC29192.1 - 0.009 15.7 6.5 0.024 14.4 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger LapA_dom PF06305.11 EGC29192.1 - 0.11 12.4 0.4 0.11 12.4 0.4 2.7 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain 7tm_1 PF00001.21 EGC29192.1 - 0.46 9.8 2.7 13 5.0 1.3 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) zf-RING_5 PF14634.6 EGC29192.1 - 0.52 10.3 16.9 0.97 9.5 16.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC29192.1 - 2.3 8.4 15.0 6.5 7.0 15.0 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Pkinase PF00069.25 EGC29193.1 - 4.6e-64 216.3 1.0 4.6e-64 216.3 1.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29193.1 - 1.9e-38 132.2 0.4 1.9e-38 132.2 0.4 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC29193.1 - 0.00024 20.0 0.2 0.00024 20.0 0.2 3.1 2 1 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGC29193.1 - 0.0074 15.7 0.0 0.022 14.1 0.0 1.8 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC29193.1 - 0.017 15.0 0.0 0.055 13.4 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family NHL PF01436.21 EGC29193.1 - 0.099 12.7 0.1 0.37 10.9 0.0 2.0 2 0 0 2 2 2 0 NHL repeat FTA2 PF13095.6 EGC29193.1 - 0.19 11.3 9.7 0.32 10.6 0.1 2.5 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kinesin_assoc PF16183.5 EGC29193.1 - 7.8 6.6 13.7 4.9 7.3 1.4 3.0 3 0 0 3 3 3 0 Kinesin-associated DUF373 PF04123.13 EGC29195.1 - 0.11 11.9 5.0 0.16 11.4 5.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Abhydrolase_6 PF12697.7 EGC29196.1 - 2e-19 71.1 0.0 3e-19 70.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC29196.1 - 3.4e-10 39.6 0.0 5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGC29196.1 - 6.1e-07 29.3 0.1 1.8e-06 27.8 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.13 EGC29196.1 - 5.2e-05 23.1 0.1 9.8e-05 22.2 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EGC29196.1 - 0.00022 21.1 0.3 0.00086 19.2 0.0 2.1 3 0 0 3 3 3 1 Lipase (class 3) Abhydrolase_2 PF02230.16 EGC29196.1 - 0.0016 18.3 0.2 0.058 13.2 0.2 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase DUF1749 PF08538.10 EGC29196.1 - 0.0035 16.5 0.1 0.005 16.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF676 PF05057.14 EGC29196.1 - 0.004 16.7 0.2 0.0056 16.2 0.2 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.7 EGC29196.1 - 0.0056 15.6 0.0 0.0078 15.2 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme DUF1057 PF06342.12 EGC29196.1 - 0.0063 15.6 0.0 0.0083 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) PAF-AH_p_II PF03403.13 EGC29196.1 - 0.018 13.6 0.0 0.031 12.8 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Chlorophyllase PF07224.11 EGC29196.1 - 0.023 13.7 0.0 0.038 13.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase LIDHydrolase PF10230.9 EGC29196.1 - 0.023 14.2 0.1 0.034 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Abhydrolase_3 PF07859.13 EGC29196.1 - 0.025 14.4 0.1 1.5 8.7 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EGC29196.1 - 0.025 14.7 0.0 0.042 14.0 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Abhydrolase_5 PF12695.7 EGC29196.1 - 0.078 12.7 0.0 0.13 12.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DLH PF01738.18 EGC29196.1 - 0.11 12.0 0.0 0.23 11.0 0.0 1.6 1 0 0 1 1 1 0 Dienelactone hydrolase family Esterase PF00756.20 EGC29196.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase HEPN_AbiU2 PF18734.1 EGC29197.1 - 0.038 13.5 1.4 0.26 10.7 0.2 2.2 1 1 1 2 2 2 0 AbiU2 MFS_1 PF07690.16 EGC29199.1 - 6.2e-27 94.4 44.9 4e-23 81.9 34.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGC29199.1 - 5 5.4 15.1 2.7 6.3 6.5 2.0 1 1 1 2 2 2 0 Transmembrane secretion effector NAD_binding_10 PF13460.6 EGC29200.1 - 0.0013 18.6 0.0 0.048 13.6 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGC29200.1 - 0.0018 17.9 0.1 0.0053 16.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family NAD_binding_1 PF00175.21 EGC29201.1 - 3.1e-15 56.8 0.1 2e-14 54.2 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGC29201.1 - 4.8e-08 33.3 0.1 1.3e-05 25.4 0.0 2.9 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Globin PF00042.22 EGC29201.1 - 2.4e-07 31.3 0.0 5.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.24 EGC29201.1 - 0.00033 21.0 0.0 0.0013 19.1 0.0 2.1 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.8 EGC29201.1 - 0.038 13.9 0.2 0.09 12.7 0.0 1.7 2 0 0 2 2 2 0 Protoglobin PAH PF02671.21 EGC29201.1 - 0.067 13.3 1.0 2.4 8.3 0.0 2.8 3 0 0 3 3 3 0 Paired amphipathic helix repeat Ras PF00071.22 EGC29202.1 - 2.5e-22 79.2 0.5 3.1e-22 78.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC29202.1 - 2.8e-07 30.7 0.0 5.1e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC29202.1 - 0.012 15.0 0.0 0.025 14.0 0.0 1.6 1 1 0 1 1 1 0 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC29202.1 - 0.02 14.2 0.8 0.039 13.3 0.8 1.7 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region TFX_C PF14601.6 EGC29202.1 - 0.15 12.1 0.6 0.22 11.5 0.1 1.6 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term zf-U1 PF06220.12 EGC29203.1 - 1.7e-08 34.1 3.7 3.3e-08 33.2 3.7 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.8 EGC29203.1 - 0.028 14.7 6.9 0.12 12.7 6.9 2.2 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Mucin PF01456.17 EGC29203.1 - 1.3 9.0 7.5 5 7.1 0.5 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein G-patch PF01585.23 EGC29204.1 - 3.5e-10 39.6 3.1 7.4e-10 38.6 3.1 1.6 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGC29204.1 - 0.00077 19.5 0.3 0.00077 19.5 0.3 5.7 6 1 0 6 6 6 1 G-patch domain DUF3439 PF11921.8 EGC29204.1 - 0.61 10.1 23.2 2.1 8.3 7.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC29204.1 - 4.2 7.3 38.6 0.58 10.1 8.6 2.7 3 0 0 3 3 3 0 Mucin-like glycoprotein DUF4834 PF16118.5 EGC29205.1 - 0.0044 17.9 0.8 0.0051 17.7 0.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF4064 PF13273.6 EGC29205.1 - 0.027 14.7 0.0 0.029 14.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) SID-1_RNA_chan PF13965.6 EGC29205.1 - 0.046 12.1 0.6 0.044 12.2 0.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 EphA2_TM PF14575.6 EGC29205.1 - 0.061 14.2 0.0 0.072 14.0 0.0 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Vps55 PF04133.14 EGC29205.1 - 0.081 12.9 0.0 0.095 12.7 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting 55 PepSY_TM_like_2 PF16357.5 EGC29205.1 - 0.18 11.8 0.9 0.21 11.5 0.9 1.1 1 0 0 1 1 1 0 Putative PepSY_TM-like Spt20 PF12090.8 EGC29205.1 - 5.7 6.5 18.0 6.1 6.4 18.0 1.1 1 0 0 1 1 1 0 Spt20 family Pal1 PF08316.11 EGC29206.1 - 0.066 14.0 6.0 0.078 13.7 6.0 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DDHD PF02862.17 EGC29206.1 - 0.45 10.6 11.5 0.52 10.4 11.5 1.1 1 0 0 1 1 1 0 DDHD domain Trypan_glycop PF00913.19 EGC29206.1 - 3.3 6.9 12.6 3.6 6.7 12.6 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF2828 PF11443.8 EGC29206.1 - 8.3 4.4 17.6 10 4.1 17.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) EGF_2 PF07974.13 EGC29207.1 - 3.2e-05 24.2 7.0 6.6e-05 23.2 7.0 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGC29207.1 - 0.0011 19.0 7.0 0.0019 18.3 7.0 1.4 1 0 0 1 1 1 1 Laminin EGF domain EGF_Tenascin PF18720.1 EGC29207.1 - 0.0044 17.0 5.1 0.0084 16.1 5.1 1.4 1 1 0 1 1 1 1 Tenascin EGF domain EGF_alliinase PF04863.13 EGC29207.1 - 0.02 15.3 4.6 0.037 14.4 4.6 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain V-SNARE_C PF12352.8 EGC29208.1 - 1.4e-05 25.2 1.4 1.4e-05 25.2 1.4 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF2205 PF10224.9 EGC29208.1 - 0.0021 18.0 1.9 0.039 13.9 0.4 3.0 2 1 0 2 2 2 1 Short coiled-coil protein DUF848 PF05852.11 EGC29208.1 - 0.0028 17.8 1.5 0.0028 17.8 1.5 2.1 1 1 1 2 2 2 1 Gammaherpesvirus protein of unknown function (DUF848) DUF948 PF06103.11 EGC29208.1 - 0.027 14.7 0.6 7.7 6.9 0.0 2.5 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) FAM131 PF15010.6 EGC29208.1 - 0.042 13.8 0.3 0.057 13.3 0.3 1.2 1 0 0 1 1 1 0 Putative cell signalling DUF1307 PF06998.11 EGC29208.1 - 0.049 13.6 3.2 0.89 9.6 0.7 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1307) XhlA PF10779.9 EGC29208.1 - 0.32 11.2 9.5 2.8 8.2 0.0 3.8 3 1 1 4 4 4 0 Haemolysin XhlA DASH_Dam1 PF08653.10 EGC29208.1 - 0.47 10.3 4.4 5.1 7.0 0.2 3.2 2 1 1 3 3 3 0 DASH complex subunit Dam1 Sec20 PF03908.13 EGC29208.1 - 0.57 10.1 7.9 0.6 10.1 0.1 3.4 2 1 2 4 4 4 0 Sec20 BRE1 PF08647.11 EGC29208.1 - 1.1 9.4 7.6 1.4 9.1 3.1 3.1 1 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase DUF4407 PF14362.6 EGC29208.1 - 5.2 6.3 6.7 14 5.0 6.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) OTU PF02338.19 EGC29209.1 - 2e-09 38.0 0.1 2.5e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease CCDC84 PF14968.6 EGC29210.1 - 0.015 15.0 1.9 0.028 14.0 1.9 1.5 1 0 0 1 1 1 0 Coiled coil protein 84 KaiA PF07688.12 EGC29210.1 - 0.047 13.8 8.3 1.8 8.7 0.0 2.8 2 1 1 3 3 3 0 KaiA C-terminal domain tRNA-synt_1 PF00133.22 EGC29212.1 - 2e-188 627.5 0.0 2.2e-187 624.0 0.0 2.0 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC29212.1 - 3.7e-37 127.6 2.0 8.2e-37 126.5 2.0 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGC29212.1 - 1.2e-18 67.1 0.3 1.7e-08 33.7 0.0 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGC29212.1 - 8.6e-08 31.9 0.0 8.2e-05 22.2 0.0 2.9 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGC29212.1 - 0.0027 17.1 0.0 1.2 8.4 0.0 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (C) catalytic domain Val_tRNA-synt_C PF10458.9 EGC29212.1 - 0.061 13.6 1.7 0.18 12.1 1.7 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm Syntaxin-6_N PF09177.11 EGC29212.1 - 0.63 10.6 4.2 0.93 10.1 2.5 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal ABC_tran_CTD PF16326.5 EGC29212.1 - 1.4 9.3 5.1 4.3 7.7 5.1 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain Exo_endo_phos PF03372.23 EGC29213.1 - 2.5e-06 27.2 0.0 1.4e-05 24.8 0.0 2.2 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CoA_binding PF02629.19 EGC29214.1 - 8e-32 109.8 0.8 8e-32 109.8 0.8 1.8 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.19 EGC29214.1 - 1.2e-23 83.6 0.1 3.6e-23 82.1 0.1 1.8 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.6 EGC29214.1 - 1.6e-08 34.5 0.0 5.4e-08 32.7 0.0 1.9 2 1 1 3 3 3 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.6 EGC29214.1 - 0.0046 17.4 0.0 0.014 15.9 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain Ribul_P_3_epim PF00834.19 EGC29214.1 - 0.021 14.2 0.1 0.036 13.4 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Peptidase_M48 PF01435.18 EGC29215.1 - 2e-33 115.8 0.0 3.3e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Aspzincin_M35 PF14521.6 EGC29215.1 - 0.0012 19.4 0.1 0.0051 17.4 0.0 1.8 2 0 0 2 2 2 1 Lysine-specific metallo-endopeptidase TFIIA PF03153.13 EGC29216.1 - 2.6 7.9 41.2 3.2 7.7 41.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit LAP1C PF05609.12 EGC29216.1 - 4 6.4 28.1 4.8 6.2 28.1 1.0 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAT1 PF09770.9 EGC29216.1 - 5.2 5.2 36.8 5.3 5.2 36.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 RabGAP-TBC PF00566.18 EGC29217.1 - 6.9e-29 101.0 24.6 2.2e-17 63.4 1.1 4.1 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Na_H_Exchanger PF00999.21 EGC29218.1 - 2.3e-59 201.1 50.5 3.1e-59 200.7 50.5 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF2407_C PF13373.6 EGC29218.1 - 0.13 12.5 3.1 2.2 8.5 0.1 3.1 2 1 0 2 2 2 0 DUF2407 C-terminal domain DnaJ PF00226.31 EGC29219.1 - 8.4e-24 83.5 0.2 1.8e-23 82.4 0.2 1.6 1 0 0 1 1 1 1 DnaJ domain DUF1836 PF08876.11 EGC29219.1 - 0.0048 16.9 0.3 0.011 15.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1836) Mucin PF01456.17 EGC29219.1 - 0.56 10.2 19.1 0.93 9.5 19.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGC29219.1 - 7.4 4.6 15.0 11 4.1 15.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DFP PF04127.15 EGC29221.1 - 8e-15 55.1 0.0 3.7e-10 39.9 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein EbsA PF17255.2 EGC29221.1 - 0.067 13.5 0.1 0.19 12.1 0.1 1.8 1 0 0 1 1 1 0 EbsA-like protein Pkinase_Tyr PF07714.17 EGC29222.1 - 7.5e-51 172.9 0.0 1.1e-50 172.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC29222.1 - 4.6e-45 154.0 0.0 2.9e-44 151.4 0.0 2.2 2 1 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGC29222.1 - 0.083 12.8 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC29222.1 - 0.13 11.6 0.0 0.21 10.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF515 PF04415.12 EGC29223.1 - 2.4 6.4 6.2 3.2 6.0 6.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Sod_Fe_C PF02777.18 EGC29225.1 - 6.6e-39 132.2 0.6 1.2e-38 131.4 0.2 1.6 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.22 EGC29225.1 - 3.4e-32 110.8 1.2 3.4e-32 110.8 1.2 1.7 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CesT PF05932.13 EGC29225.1 - 0.12 12.5 0.0 0.18 11.9 0.0 1.3 1 0 0 1 1 1 0 Tir chaperone protein (CesT) family NUDIX PF00293.28 EGC29226.1 - 2.6e-10 40.4 0.0 4.2e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain YolD PF08863.10 EGC29226.1 - 0.03 14.4 0.4 0.12 12.5 0.1 2.0 2 0 0 2 2 2 0 YolD-like protein Profilin PF00235.19 EGC29227.1 - 3e-42 143.9 0.9 3.3e-42 143.8 0.9 1.0 1 0 0 1 1 1 1 Profilin XPG_I_2 PF12813.7 EGC29229.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.18 EGC29229.1 - 2e-05 24.8 0.0 4.5e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGC29229.1 - 7e-05 23.2 0.1 0.0002 21.8 0.1 1.8 1 0 0 1 1 1 1 XPG N-terminal domain HECA PF15353.6 EGC29229.1 - 0.1 12.8 0.7 0.38 11.0 0.1 2.2 2 1 1 3 3 3 0 Headcase protein family homologue UFD1 PF03152.14 EGC29230.1 - 1.1e-75 252.9 0.1 1.3e-75 252.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.17 EGC29230.1 - 0.097 12.5 0.0 0.24 11.2 0.0 1.6 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Yip1 PF04893.17 EGC29231.1 - 1.6e-07 31.2 14.2 5.5e-06 26.2 9.8 2.2 1 1 1 2 2 2 2 Yip1 domain TGBp3 PF02495.17 EGC29232.1 - 4 7.2 8.8 0.39 10.4 0.1 2.9 3 0 0 3 3 3 0 Triple gene block 3 TPR_2 PF07719.17 EGC29233.1 - 4.3e-29 98.2 5.4 0.00077 19.4 0.0 12.1 12 0 0 12 12 11 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGC29233.1 - 2e-23 81.2 17.3 3.4e-05 23.5 0.0 11.8 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGC29233.1 - 3.8e-18 64.6 0.1 0.019 15.8 0.3 8.9 6 2 2 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC29233.1 - 9.3e-18 64.5 14.7 4.1e-05 24.0 0.0 8.1 7 1 2 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGC29233.1 - 2.5e-17 63.2 0.0 0.0061 17.2 0.0 5.8 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC29233.1 - 7.6e-16 56.9 22.7 0.00016 21.6 0.0 11.0 11 0 0 11 11 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC29233.1 - 5.6e-12 45.1 18.2 0.0079 15.9 0.1 7.5 8 0 0 8 8 7 4 TPR repeat TPR_9 PF13371.6 EGC29233.1 - 1.8e-10 40.8 0.0 0.029 14.5 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC29233.1 - 1.9e-08 33.7 2.0 1.7 8.8 0.1 7.8 9 0 0 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC29233.1 - 2.5e-08 34.0 30.5 0.00059 20.0 0.1 8.0 4 3 2 8 8 7 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC29233.1 - 7.5e-07 29.4 13.2 0.42 11.4 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC29233.1 - 2.9e-06 27.5 18.5 0.42 10.9 1.5 8.6 5 3 3 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC29233.1 - 8e-06 25.9 27.0 13 6.5 0.0 12.0 12 1 0 12 12 12 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGC29233.1 - 3.8e-05 23.7 0.0 0.00019 21.4 0.0 2.2 1 1 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 ChAPs PF09295.10 EGC29233.1 - 0.0024 17.0 10.3 0.014 14.4 0.4 3.9 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) ANAPC5 PF12862.7 EGC29233.1 - 0.014 15.4 1.4 1.4 9.1 0.2 3.7 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 5 TFIIA PF03153.13 EGC29233.1 - 0.037 14.0 8.7 0.075 13.0 8.7 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Androgen_recep PF02166.16 EGC29233.1 - 0.75 8.6 9.4 1.5 7.5 9.4 1.4 1 0 0 1 1 1 0 Androgen receptor TPR_15 PF13429.6 EGC29233.1 - 0.8 8.9 19.9 0.75 9.0 0.1 5.4 5 1 0 5 5 5 0 Tetratricopeptide repeat DUF4794 PF16042.5 EGC29233.1 - 0.84 10.7 5.0 2 9.4 5.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4794) 3-HAO PF06052.12 EGC29234.1 - 1.8e-60 203.0 0.1 2.1e-60 202.7 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.11 EGC29234.1 - 1.8e-06 27.6 0.0 2.4e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.22 EGC29234.1 - 0.089 12.4 0.0 0.12 12.0 0.0 1.5 1 1 0 1 1 1 0 Cupin DDE_Tnp_4 PF13359.6 EGC29235.1 - 2e-13 50.3 0.0 2.9e-13 49.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pox_ser-thr_kin PF05445.11 EGC29235.1 - 0.0066 15.5 3.2 0.0099 14.9 0.1 2.0 2 0 0 2 2 2 1 Poxvirus serine/threonine protein kinase GP3_package PF16677.5 EGC29235.1 - 0.021 15.0 0.1 0.052 13.7 0.1 1.6 1 0 0 1 1 1 0 DNA-packaging protein gp3 Pterin_4a PF01329.19 EGC29236.1 - 2.9e-30 104.3 0.1 3.4e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase P34-Arc PF04045.14 EGC29237.1 - 1.4e-34 119.9 0.0 1.8e-34 119.5 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DEAD PF00270.29 EGC29238.1 - 6.6e-49 166.0 0.0 1.4e-48 165.0 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC29238.1 - 3.1e-26 91.9 0.0 2.9e-25 88.8 0.0 2.6 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGC29238.1 - 9.4e-19 67.4 0.4 1.8e-18 66.5 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) PQQ_2 PF13360.6 EGC29239.1 - 0.058 13.0 0.3 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 PQQ-like domain Zw10 PF06248.13 EGC29240.1 - 1.6e-34 119.4 47.3 1e-33 116.8 41.7 2.7 2 1 0 2 2 2 1 Centromere/kinetochore Zw10 FadA PF09403.10 EGC29240.1 - 0.023 15.1 2.2 0.023 15.1 2.2 3.7 4 0 0 4 4 4 0 Adhesion protein FadA DUF4776 PF16003.5 EGC29240.1 - 0.095 11.7 6.5 0.18 10.7 6.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) Myc-LZ PF02344.15 EGC29240.1 - 0.73 10.0 6.1 0.16 12.1 1.8 2.2 2 0 0 2 2 2 0 Myc leucine zipper domain Med4 PF10018.9 EGC29240.1 - 7.4 6.2 18.4 12 5.5 7.2 4.4 3 1 1 4 4 4 0 Vitamin-D-receptor interacting Mediator subunit 4 Vps26 PF03643.15 EGC29242.1 - 1.9e-121 404.3 5.8 3.9e-121 403.3 5.8 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 FNIP PF05725.12 EGC29242.1 - 7.3e-91 298.1 50.8 2e-14 53.4 0.1 8.8 4 1 4 9 9 9 9 FNIP Repeat tRNA-synt_2 PF00152.20 EGC29242.1 - 1.4e-81 274.0 0.0 2.3e-81 273.3 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) GAD PF02938.14 EGC29242.1 - 9.9e-10 38.5 0.3 2.5e-09 37.2 0.0 1.9 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.25 EGC29242.1 - 1.8e-09 37.5 0.3 4.6e-09 36.2 0.3 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGC29242.1 - 0.018 14.5 0.0 0.039 13.4 0.1 1.6 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) DUF2057 PF09829.9 EGC29243.1 - 0.0021 18.2 0.1 5.6 7.1 0.0 3.5 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2057) Med20 PF08612.11 EGC29243.1 - 0.013 14.9 0.3 0.72 9.2 0.1 2.4 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_transf_36 PF06165.11 EGC29243.1 - 0.032 13.6 0.1 28 4.0 0.1 3.3 3 0 0 3 3 3 0 Glycosyltransferase family 36 DUF2458 PF10454.9 EGC29243.1 - 0.037 13.7 0.6 3.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) YwpF PF14183.6 EGC29243.1 - 0.15 12.0 0.4 20 5.2 0.0 2.4 2 0 0 2 2 2 0 YwpF-like protein zf-RING_2 PF13639.6 EGC29247.1 - 2.6e-09 37.2 8.9 6.5e-09 36.0 8.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29247.1 - 3.7e-09 36.3 5.7 7.3e-09 35.4 5.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29247.1 - 1.7e-08 34.2 8.9 3.4e-08 33.2 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29247.1 - 8.9e-07 28.7 9.9 2.5e-06 27.3 9.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29247.1 - 2.1e-06 27.6 5.0 5.9e-06 26.2 5.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC29247.1 - 4.5e-05 23.3 7.3 0.00012 22.0 7.3 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC29247.1 - 0.0005 19.8 7.7 0.0014 18.3 7.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC29247.1 - 0.00057 20.0 9.1 0.0015 18.6 9.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC29247.1 - 0.0014 18.4 8.4 0.0032 17.2 8.4 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC29247.1 - 0.0022 18.2 5.1 0.0075 16.5 5.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC29247.1 - 0.01 15.7 2.0 0.023 14.6 2.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGC29247.1 - 0.017 14.9 7.2 0.042 13.7 7.2 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGC29247.1 - 0.09 12.4 3.9 0.18 11.4 3.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Fer4_14 PF13394.6 EGC29247.1 - 0.22 11.6 0.0 0.22 11.6 0.0 3.2 3 1 0 3 3 1 0 4Fe-4S single cluster domain DZR PF12773.7 EGC29247.1 - 0.48 10.5 5.5 1.3 9.1 5.2 1.8 1 1 0 1 1 1 0 Double zinc ribbon WD40 PF00400.32 EGC29250.1 - 2.6e-32 110.3 21.7 9e-08 32.7 0.3 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC29250.1 - 4.1e-10 39.8 1.8 0.026 14.8 0.0 4.6 1 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGC29250.1 - 0.00056 18.8 3.7 0.14 10.9 0.2 2.7 1 1 0 2 2 2 2 Nup133 N terminal like DUF4221 PF13970.6 EGC29250.1 - 0.0019 17.8 4.0 0.0019 17.8 4.0 2.5 1 1 2 3 3 3 1 Domain of unknown function (DUF4221) Etmic-2 PF06670.11 EGC29250.1 - 0.1 11.5 0.1 0.15 11.0 0.1 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Ependymin PF00811.18 EGC29250.1 - 0.11 12.8 2.4 0.71 10.1 0.3 2.4 1 1 1 2 2 2 0 Ependymin Prefoldin PF02996.17 EGC29251.1 - 3.3e-20 72.2 1.5 3.3e-20 72.2 1.5 3.1 3 1 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.6 EGC29251.1 - 4.5e-07 29.9 0.1 4.5e-07 29.9 0.1 3.9 3 1 1 4 4 4 1 Prefoldin subunit Peptidase_S9 PF00326.21 EGC29252.1 - 0.011 15.2 0.0 0.047 13.2 0.0 2.0 1 1 0 1 1 1 0 Prolyl oligopeptidase family SIR2_2 PF13289.6 EGC29252.1 - 0.069 13.3 0.0 0.27 11.4 0.0 1.9 2 0 0 2 2 2 0 SIR2-like domain adh_short PF00106.25 EGC29253.1 - 0.0052 16.2 0.1 0.0077 15.7 0.1 1.3 1 1 0 1 1 1 1 short chain dehydrogenase AAA_35 PF14516.6 EGC29253.1 - 0.026 13.4 0.0 0.033 13.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain adh_short_C2 PF13561.6 EGC29253.1 - 0.035 13.7 0.0 0.041 13.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Ycf15 PF10705.9 EGC29253.1 - 0.1 12.8 0.0 0.24 11.6 0.0 1.6 1 1 0 1 1 1 0 Chloroplast protein precursor Ycf15 putative Pkinase_Tyr PF07714.17 EGC29254.1 - 2.1e-61 207.5 0.0 2.7e-61 207.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC29254.1 - 1.4e-58 198.4 0.0 1.9e-58 197.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGC29254.1 - 0.0034 17.3 0.0 0.0087 16.0 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mid2 PF04478.12 EGC29254.1 - 0.0046 16.8 0.2 0.01 15.7 0.2 1.5 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.6 EGC29254.1 - 0.021 14.7 2.5 0.025 14.5 0.3 1.9 2 0 0 2 2 2 0 TMEM154 protein family Haspin_kinase PF12330.8 EGC29254.1 - 0.036 13.0 2.0 0.26 10.2 0.0 2.4 3 0 0 3 3 3 0 Haspin like kinase domain TMEM119 PF15724.5 EGC29254.1 - 0.038 14.1 0.4 0.057 13.5 0.4 1.2 1 0 0 1 1 1 0 TMEM119 family MLANA PF14991.6 EGC29254.1 - 0.056 13.7 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Protein melan-A ETRAMP PF09716.10 EGC29254.1 - 0.089 12.9 0.4 2.7 8.1 0.2 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pkinase_fungal PF17667.1 EGC29254.1 - 0.13 11.0 0.0 0.18 10.5 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF3139 PF11337.8 EGC29254.1 - 0.19 12.4 11.2 0.95 10.2 3.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Cation_ATPase_C PF00689.21 EGC29255.1 - 1.7e-44 151.7 4.0 1.7e-44 151.7 4.0 2.9 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGC29255.1 - 1.3e-40 138.9 0.2 1.3e-40 138.9 0.2 3.0 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGC29255.1 - 1.9e-19 69.5 0.1 4.2e-19 68.4 0.1 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC29255.1 - 9.1e-18 65.3 0.0 8.4e-17 62.2 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC29255.1 - 9.5e-13 47.6 0.1 3.1e-12 46.0 0.1 2.0 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGC29255.1 - 9.7e-06 25.5 0.1 0.0022 17.8 0.1 2.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase ABC_membrane_3 PF13748.6 EGC29255.1 - 0.015 14.5 0.1 0.039 13.2 0.1 1.6 1 0 0 1 1 1 0 ABC transporter transmembrane region Ferlin_C PF16165.5 EGC29255.1 - 0.035 14.1 0.0 0.17 11.8 0.0 2.2 1 0 0 1 1 1 0 Ferlin C-terminus Tho1_MOS11_C PF18592.1 EGC29255.1 - 0.055 13.3 0.0 0.36 10.7 0.0 2.1 2 0 0 2 2 2 0 Tho1/MOS11 C-terminal domain Phage_holin_3_6 PF07332.11 EGC29255.1 - 0.12 12.4 5.2 0.84 9.7 1.9 2.8 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4199 PF13858.6 EGC29255.1 - 0.46 10.9 6.0 3.2 8.1 2.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) Complex1_LYR PF05347.15 EGC29256.1 - 3e-10 40.0 1.7 4.6e-10 39.4 1.7 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC29256.1 - 0.0026 18.5 0.4 0.0031 18.2 0.4 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PPV_E1_N PF00524.18 EGC29256.1 - 0.054 13.9 1.2 0.077 13.4 0.3 1.7 1 1 0 2 2 2 0 E1 Protein, N terminal domain MreB_Mbl PF06723.13 EGC29256.1 - 0.24 10.2 0.0 0.28 10.0 0.0 1.1 1 0 0 1 1 1 0 MreB/Mbl protein DUF3172 PF11371.8 EGC29257.1 - 0.047 13.4 0.0 0.057 13.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) IBR PF01485.21 EGC29258.1 - 8.3e-25 86.8 44.8 8.9e-16 57.9 4.1 4.4 3 1 0 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGC29258.1 - 1.7e-05 24.5 4.9 1.7e-05 24.5 4.9 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29258.1 - 0.0015 18.4 7.7 0.0015 18.4 7.7 3.9 3 2 1 4 4 4 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC29258.1 - 0.0046 16.8 4.9 0.0046 16.8 4.9 5.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC29258.1 - 0.0053 17.1 7.3 0.0053 17.1 7.3 4.5 3 2 1 4 4 4 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC29258.1 - 0.021 14.9 6.4 0.021 14.9 6.4 4.1 4 1 0 4 4 4 0 RING-type zinc-finger Zn-ribbon_8 PF09723.10 EGC29258.1 - 0.25 11.5 0.3 0.25 11.5 0.3 5.1 5 2 1 6 6 6 0 Zinc ribbon domain IBR PF01485.21 EGC29260.1 - 9.6e-20 70.6 33.0 4e-13 49.4 8.1 4.1 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_5 PF14634.6 EGC29260.1 - 1.8e-06 27.8 10.5 1.8e-06 27.8 10.5 3.6 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGC29260.1 - 0.0019 18.5 9.4 0.0019 18.5 9.4 4.5 3 2 1 4 4 4 2 Ring finger domain zf-C3HC4 PF00097.25 EGC29260.1 - 0.025 14.5 12.0 0.025 14.5 12.0 5.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf_Rg PF17915.1 EGC29260.1 - 0.032 13.6 4.3 0.032 13.6 4.3 4.2 5 0 0 5 5 5 0 Reverse gyrase zinc finger Glyco_hydro_4C PF11975.8 EGC29261.1 - 0.15 12.1 2.4 0.49 10.4 2.4 1.9 1 0 0 1 1 1 0 Family 4 glycosyl hydrolase C-terminal domain SARAF PF06682.12 EGC29262.1 - 0.062 13.0 14.0 0.056 13.1 0.7 2.4 1 1 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis DUF4834 PF16118.5 EGC29262.1 - 0.17 12.8 9.8 2.6 9.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) ATP-synt_8 PF00895.20 EGC29262.1 - 4.1 7.9 6.5 1.3 9.6 1.6 2.6 1 1 1 2 2 2 0 ATP synthase protein 8 Zip PF02535.22 EGC29262.1 - 8.8 5.4 5.1 7.8 5.6 0.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Spt4 PF06093.13 EGC29265.1 - 2.4e-24 85.2 0.2 2.9e-24 85.0 0.2 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger BaffR-Tall_bind PF09256.10 EGC29265.1 - 0.063 13.1 0.1 0.11 12.3 0.1 1.4 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding FNIP PF05725.12 EGC29266.1 - 8.9e-58 192.2 45.1 2.8e-08 33.8 0.8 9.1 5 2 5 10 10 10 10 FNIP Repeat VPS28 PF03997.12 EGC29267.1 - 8.7e-67 224.5 1.1 1.1e-66 224.2 1.1 1.1 1 0 0 1 1 1 1 VPS28 protein PilM_2 PF11104.8 EGC29267.1 - 0.074 12.1 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Aa_trans PF01490.18 EGC29268.1 - 6.1e-10 38.4 38.9 9.9e-10 37.7 38.9 1.4 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.13 EGC29268.1 - 0.69 8.9 32.0 6.3 5.7 26.6 3.1 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family DEAD PF00270.29 EGC29269.1 - 4.2e-19 69.0 0.0 1.1e-18 67.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC29269.1 - 4.1e-18 65.7 0.8 1.7e-17 63.7 0.1 2.5 2 1 1 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.10 EGC29269.1 - 2.1e-16 59.7 0.1 6.8e-16 58.1 0.1 1.9 1 0 0 1 1 1 1 RQC domain HRDC PF00570.23 EGC29269.1 - 1.4e-11 44.2 0.0 3.3e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 HRDC domain RecQ_Zn_bind PF16124.5 EGC29269.1 - 1.5e-11 44.8 0.4 4.1e-10 40.2 0.2 2.7 2 0 0 2 2 2 1 RecQ zinc-binding NumbF PF06311.12 EGC29269.1 - 0.016 15.8 0.8 0.056 14.0 0.8 1.9 1 0 0 1 1 1 0 NUMB domain Abhydrolase_2 PF02230.16 EGC29270.1 - 1.9e-39 135.7 0.0 2.1e-39 135.5 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGC29270.1 - 0.0002 21.1 0.0 0.00063 19.5 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase (FSH1) DLH PF01738.18 EGC29270.1 - 0.00055 19.5 0.0 0.00078 19.1 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGC29270.1 - 0.0025 17.3 0.2 0.026 14.0 0.0 2.4 2 1 0 3 3 3 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC29270.1 - 0.0028 17.0 0.0 0.14 11.4 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGC29270.1 - 0.0063 16.2 0.9 2.5 7.7 0.1 3.0 1 1 2 3 3 3 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC29270.1 - 0.0064 17.1 0.0 0.0098 16.5 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.9 EGC29270.1 - 0.25 10.8 0.0 0.82 9.1 0.0 1.7 2 0 0 2 2 2 0 Esterase PHB depolymerase DUF4834 PF16118.5 EGC29272.1 - 0.0065 17.4 1.3 0.01 16.8 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) O-antigen_lig PF13425.6 EGC29272.1 - 0.0088 14.9 2.1 0.011 14.6 2.1 1.2 1 0 0 1 1 1 1 O-antigen ligase like membrane protein DUF3854 PF12965.7 EGC29272.1 - 0.019 15.0 0.4 0.025 14.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) SR-25 PF10500.9 EGC29274.1 - 0.21 11.2 7.0 0.35 10.5 7.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.18 EGC29275.1 - 1.9e-57 194.4 1.9 5.2e-57 192.9 1.9 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank PF00023.30 EGC29275.1 - 1.1e-08 35.1 0.2 2e-06 28.0 0.3 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGC29275.1 - 1.6e-08 35.0 0.2 7.4e-08 32.9 0.2 2.2 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC29275.1 - 1.1e-07 31.9 0.0 6.4e-07 29.5 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC29275.1 - 4.9e-07 29.6 0.0 0.00025 21.3 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGC29275.1 - 5.4e-05 23.7 0.0 0.0014 19.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) RseC_MucC PF04246.12 EGC29276.1 - 0.24 11.3 1.5 0.29 11.1 1.5 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Dynamin_N PF00350.23 EGC29277.1 - 3.5e-22 79.2 0.8 1.3e-11 44.9 0.0 4.1 3 2 2 5 5 5 2 Dynamin family MMR_HSR1 PF01926.23 EGC29277.1 - 3e-12 46.6 0.1 3e-12 46.6 0.1 3.1 2 1 0 3 3 3 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC29277.1 - 2.5e-06 27.5 1.0 0.055 13.4 0.0 3.1 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC29277.1 - 2.8e-06 27.0 2.5 6.6e-06 25.8 1.6 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGC29277.1 - 0.00032 20.1 0.6 0.00032 20.1 0.6 2.7 2 1 0 2 2 2 1 AIG1 family FeoB_N PF02421.18 EGC29277.1 - 0.00071 19.1 0.3 0.85 9.1 0.0 2.7 2 0 0 2 2 2 2 Ferrous iron transport protein B Roc PF08477.13 EGC29277.1 - 0.0011 19.2 2.0 0.014 15.6 0.1 3.4 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRI PF08236.11 EGC29277.1 - 0.0029 17.7 6.0 0.085 13.0 0.3 3.9 3 0 0 3 3 3 1 SRI (Set2 Rpb1 interacting) domain ATP_bind_1 PF03029.17 EGC29277.1 - 0.054 13.3 2.5 1.1 9.0 0.1 3.0 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein FtsK_SpoIIIE PF01580.18 EGC29277.1 - 0.066 12.6 0.4 0.62 9.4 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ATP-cone PF03477.16 EGC29277.1 - 0.078 13.6 1.7 0.5 11.0 0.2 3.2 2 1 1 3 3 3 0 ATP cone domain DUF948 PF06103.11 EGC29277.1 - 1.2 9.4 8.0 17 5.7 0.1 4.4 3 1 1 4 4 4 0 Bacterial protein of unknown function (DUF948) Ssu72 PF04722.13 EGC29277.1 - 3.8 7.0 10.3 4.3 6.9 1.9 3.0 2 1 0 2 2 2 0 Ssu72-like protein SAS4 PF15460.6 EGC29277.1 - 6.7 6.9 9.2 0.65 10.1 0.8 3.4 3 0 0 3 3 3 0 Something about silencing, SAS, complex subunit 4 zf-4CXXC_R1 PF10497.9 EGC29279.1 - 8.1e-09 35.6 13.6 2.6e-08 34.0 13.6 1.9 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WD40 PF00400.32 EGC29280.1 - 4.6e-17 62.1 7.6 5.6e-05 23.8 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat zf-C3HC4_2 PF13923.6 EGC29280.1 - 8.6e-09 35.1 10.0 1.6e-08 34.2 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29280.1 - 4e-08 33.2 4.1 4e-08 33.2 4.1 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGC29280.1 - 1.5e-07 31.5 4.4 3e-07 30.5 4.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_3 PF13920.6 EGC29280.1 - 1.6e-07 31.0 3.7 3e-07 30.2 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29280.1 - 3.4e-07 30.0 8.6 3.4e-07 30.0 8.6 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29280.1 - 1e-05 25.3 8.3 2.5e-05 24.1 8.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC29280.1 - 2e-05 24.6 11.9 4.5e-05 23.5 11.9 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGC29280.1 - 9.6e-05 22.6 9.4 0.0002 21.6 9.4 1.6 1 0 0 1 1 1 1 Ring finger domain F-box PF00646.33 EGC29280.1 - 0.00096 19.0 0.0 0.0021 17.9 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGC29280.1 - 0.0017 18.2 0.0 0.0027 17.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like Prok-RING_4 PF14447.6 EGC29280.1 - 0.0026 17.6 6.6 0.0062 16.4 6.6 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGC29280.1 - 0.09 12.7 3.0 0.21 11.5 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.7 EGC29280.1 - 0.84 10.0 7.9 2.1 8.7 7.9 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain Patatin PF01734.22 EGC29282.1 - 6.3e-17 62.4 0.0 1.6e-15 57.8 0.0 2.7 2 1 0 2 2 2 1 Patatin-like phospholipase DUF507 PF04368.13 EGC29282.1 - 0.045 13.7 0.6 0.15 12.0 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF507) Rrp44_S1 PF17215.3 EGC29282.1 - 0.24 11.4 1.3 3.1 7.8 0.3 2.3 1 1 1 2 2 2 0 S1 domain DNA_pol_lambd_f PF10391.9 EGC29283.1 - 0.053 13.4 0.1 0.14 12.1 0.1 1.7 1 1 0 1 1 1 0 Fingers domain of DNA polymerase lambda Microcin PF03526.13 EGC29283.1 - 0.33 10.8 5.7 3.1 7.7 1.5 2.7 1 1 2 3 3 3 0 Colicin E1 (microcin) immunity protein EGF_2 PF07974.13 EGC29284.1 - 0.18 12.2 9.1 0.41 11.1 9.1 1.7 1 0 0 1 1 1 0 EGF-like domain S_locus_glycop PF00954.20 EGC29284.1 - 0.75 10.3 4.9 0.92 10.1 0.5 3.3 3 0 0 3 3 3 0 S-locus glycoprotein domain FF PF01846.19 EGC29285.1 - 6.7e-40 135.0 31.6 1.3e-10 41.3 0.1 6.4 6 0 0 6 6 6 5 FF domain WW PF00397.26 EGC29285.1 - 4.3e-15 55.5 13.8 1.7e-07 31.2 4.8 3.4 3 0 0 3 3 3 2 WW domain Glyco_hyd_101C PF17451.2 EGC29285.1 - 0.065 13.5 2.9 0.34 11.2 0.7 2.9 2 1 1 3 3 3 0 Glycosyl hydrolase 101 beta sandwich domain FNIP PF05725.12 EGC29286.1 - 2.5e-36 123.6 53.0 1.3e-06 28.4 1.2 11.0 5 2 2 9 9 9 9 FNIP Repeat zf-B_box PF00643.24 EGC29286.1 - 1.3e-06 28.5 11.1 3e-06 27.3 11.1 1.6 1 0 0 1 1 1 1 B-box zinc finger BHD_1 PF10403.9 EGC29286.1 - 0.031 14.1 0.5 0.083 12.7 0.1 2.0 2 0 0 2 2 2 0 Rad4 beta-hairpin domain 1 CENP-B_dimeris PF09026.10 EGC29286.1 - 0.031 14.7 2.0 0.067 13.6 2.0 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CAP PF00188.26 EGC29288.1 - 1.6e-09 38.7 4.0 1.6e-09 38.7 4.0 1.7 2 0 0 2 2 2 1 Cysteine-rich secretory protein family 30K_MP_core PF17644.1 EGC29288.1 - 0.17 11.8 0.5 0.44 10.4 0.1 1.8 2 0 0 2 2 2 0 Core domain of 30K viral movement proteins Yip1 PF04893.17 EGC29289.1 - 4.8e-09 36.2 11.1 6.4e-09 35.8 11.1 1.2 1 0 0 1 1 1 1 Yip1 domain Dicty_spore_N PF04562.12 EGC29290.1 - 9.4e-58 193.9 62.1 5.3e-31 107.7 28.4 3.3 3 1 0 3 3 3 2 Dictyostelium spore coat protein, N terminus YtxH PF12732.7 EGC29291.1 - 0.0023 18.4 0.1 0.026 15.1 0.1 2.1 1 1 0 1 1 1 1 YtxH-like protein GTP_EFTU PF00009.27 EGC29292.1 - 2.5e-51 174.0 0.0 4.4e-51 173.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.12 EGC29292.1 - 1.8e-45 153.5 1.9 3.5e-45 152.5 1.9 1.5 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.24 EGC29292.1 - 7.7e-16 57.9 0.0 1.7e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC29292.1 - 8.3e-06 26.1 0.7 2e-05 24.9 0.7 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC29292.1 - 0.00018 21.5 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC29292.1 - 0.0013 18.3 0.2 0.0045 16.4 0.2 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGC29292.1 - 0.0015 18.3 0.2 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation RF3_C PF16658.5 EGC29292.1 - 0.0028 17.5 0.0 0.034 14.0 0.0 2.3 2 0 0 2 2 2 1 Class II release factor RF3, C-terminal domain Ras PF00071.22 EGC29292.1 - 0.0056 16.3 0.0 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Ras family EFG_II PF14492.6 EGC29292.1 - 0.059 13.5 0.1 0.3 11.2 0.1 2.1 1 1 0 1 1 1 0 Elongation Factor G, domain II zf-C3HC4_4 PF15227.6 EGC29294.1 - 5e-05 23.4 4.0 5e-05 23.4 4.0 2.7 2 2 1 3 3 3 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC29294.1 - 6.1e-05 22.8 8.3 6.1e-05 22.8 8.3 2.6 2 2 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC29294.1 - 0.0013 18.6 8.0 0.0013 18.6 8.0 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC29294.1 - 0.027 14.5 2.1 0.027 14.5 2.1 2.7 2 1 0 2 2 2 0 RING-type zinc-finger RNA_pol_Rpb2_7 PF04560.20 EGC29294.1 - 4.3 7.8 8.6 1.1 9.7 1.4 2.0 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 7 Gelsolin PF00626.22 EGC29295.1 - 9.4e-16 57.5 15.1 0.00037 20.3 0.0 7.6 8 0 0 8 8 8 4 Gelsolin repeat DUF4670 PF15709.5 EGC29295.1 - 0.00078 18.9 40.5 0.028 13.7 11.9 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4670) GlcNAc-1_reg PF18440.1 EGC29295.1 - 0.038 14.2 0.4 0.13 12.5 0.4 1.9 1 0 0 1 1 1 0 Putative GlcNAc-1 phosphotransferase regulatory domain Menin PF05053.13 EGC29296.1 - 0.15 10.4 10.0 0.22 9.9 10.0 1.3 1 0 0 1 1 1 0 Menin Membralin PF09746.9 EGC29296.1 - 0.27 10.2 12.4 0.52 9.3 12.4 1.4 1 0 0 1 1 1 0 Tumour-associated protein Presenilin PF01080.17 EGC29296.1 - 7.5 5.2 10.0 12 4.5 10.0 1.3 1 0 0 1 1 1 0 Presenilin Oxysterol_BP PF01237.18 EGC29297.1 - 2.8e-60 204.1 9.9 3.7e-58 197.2 9.9 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein HECT_2 PF09814.9 EGC29298.1 - 4.4e-09 35.7 1.4 5.2e-09 35.4 1.4 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GCIP PF13324.6 EGC29299.1 - 5.5e-50 170.4 21.9 1.7e-49 168.8 21.9 1.8 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting EGF_2 PF07974.13 EGC29300.1 - 0.03 14.7 9.0 0.062 13.7 9.0 1.5 1 0 0 1 1 1 0 EGF-like domain Peptidase_M20 PF01546.28 EGC29301.1 - 1.8e-23 83.3 0.0 3e-23 82.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC29301.1 - 2.3e-13 50.0 0.0 3.8e-13 49.3 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2185 PF09951.9 EGC29302.1 - 4.7e-27 93.6 0.6 1.1e-26 92.5 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2185) DUF2314 PF10077.9 EGC29302.1 - 1.7e-05 24.9 0.1 3e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) Frataxin_Cyay PF01491.16 EGC29302.1 - 0.098 12.7 1.1 2.6 8.2 0.2 2.3 2 0 0 2 2 2 0 Frataxin-like domain ERCC4 PF02732.15 EGC29303.1 - 7.5e-18 65.2 0.2 7.5e-18 65.2 0.2 5.3 4 1 0 4 4 4 1 ERCC4 domain SAM_1 PF00536.30 EGC29303.1 - 0.0046 17.4 0.0 0.014 15.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC29303.1 - 0.019 15.1 0.6 0.14 12.3 0.1 2.7 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SWIM PF04434.17 EGC29303.1 - 0.11 12.2 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 SWIM zinc finger SNARE PF05739.19 EGC29304.1 - 4.1e-05 23.5 1.4 7.2e-05 22.7 0.5 1.8 2 0 0 2 2 2 1 SNARE domain DegS PF05384.11 EGC29304.1 - 0.0017 17.9 1.8 0.055 12.9 0.1 2.6 2 0 0 2 2 2 1 Sensor protein DegS CLZ PF16526.5 EGC29304.1 - 0.021 15.1 1.1 0.021 15.1 1.1 2.5 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FliJ PF02050.16 EGC29304.1 - 0.022 15.0 3.5 0.12 12.6 0.4 2.3 2 0 0 2 2 2 0 Flagellar FliJ protein XhlA PF10779.9 EGC29304.1 - 0.032 14.4 2.1 0.032 14.4 2.1 2.9 3 2 0 3 3 3 0 Haemolysin XhlA KxDL PF10241.9 EGC29304.1 - 0.053 13.8 4.4 1.6 9.0 0.1 3.3 2 1 1 3 3 3 0 Uncharacterized conserved protein Synaptobrevin PF00957.21 EGC29304.1 - 0.091 12.6 0.1 0.3 10.9 0.1 2.0 1 0 0 1 1 1 0 Synaptobrevin ZnuA PF01297.17 EGC29304.1 - 0.16 11.3 3.0 5.3 6.4 1.8 2.2 1 1 0 2 2 2 0 Zinc-uptake complex component A periplasmic Insulin_TMD PF17870.1 EGC29304.1 - 0.41 10.8 2.3 0.71 10.0 2.3 1.4 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF948 PF06103.11 EGC29304.1 - 0.62 10.4 3.8 0.67 10.2 0.9 2.5 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) TPR_MLP1_2 PF07926.12 EGC29304.1 - 0.66 10.0 10.7 0.6 10.2 2.1 2.5 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein BLOC1_2 PF10046.9 EGC29304.1 - 0.83 10.0 7.9 0.85 10.0 1.0 2.9 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF745 PF05335.13 EGC29304.1 - 0.85 9.3 4.5 0.5 10.1 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) TMPIT PF07851.13 EGC29304.1 - 3.1 7.0 5.0 4.7 6.4 0.1 2.1 2 0 0 2 2 2 0 TMPIT-like protein DASH_Spc19 PF08287.11 EGC29304.1 - 4.1 7.3 11.2 0.78 9.6 0.8 2.5 2 1 0 2 2 2 0 Spc19 BDV_M PF16520.5 EGC29305.1 - 0.11 12.9 3.3 3.3 8.1 0.1 4.0 3 0 0 3 3 3 0 ssRNA-binding matrix protein of Bornaviridae adh_short PF00106.25 EGC29306.1 - 8.2e-37 126.6 0.0 9.8e-37 126.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC29306.1 - 2.7e-16 59.9 0.0 3.2e-16 59.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC29306.1 - 8e-09 35.7 0.0 1.1e-08 35.2 0.0 1.1 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.8 EGC29306.1 - 0.022 14.5 0.1 0.052 13.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3439 PF11921.8 EGC29307.1 - 0.83 9.6 5.1 2 8.4 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) OTU PF02338.19 EGC29309.1 - 2.5e-10 40.9 0.0 2.5e-10 40.9 0.0 2.6 2 1 0 2 2 1 1 OTU-like cysteine protease DUF572 PF04502.13 EGC29309.1 - 0.0014 18.3 6.1 0.0017 18.1 6.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF572) UPF0242 PF06785.11 EGC29309.1 - 0.0017 18.5 18.6 0.0027 17.8 18.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus HemX PF04375.14 EGC29309.1 - 0.002 17.5 17.8 0.0038 16.5 17.8 1.6 1 0 0 1 1 1 1 HemX, putative uroporphyrinogen-III C-methyltransferase Ureide_permease PF07168.11 EGC29309.1 - 0.013 14.3 0.6 0.018 13.8 0.6 1.2 1 0 0 1 1 1 0 Ureide permease TFIIA PF03153.13 EGC29309.1 - 0.013 15.5 22.0 0.016 15.2 22.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3810 PF12725.7 EGC29309.1 - 0.099 12.0 4.4 0.15 11.4 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Nucleoside_tran PF01733.18 EGC29309.1 - 0.11 11.9 3.2 0.17 11.2 3.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter LCIB_C_CA PF18599.1 EGC29309.1 - 0.11 11.7 9.6 0.18 11.1 9.6 1.2 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases Nop53 PF07767.11 EGC29309.1 - 0.17 11.2 17.5 0.23 10.8 17.5 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Neur_chan_memb PF02932.16 EGC29309.1 - 0.32 11.0 4.3 0.56 10.2 4.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region eIF3_subunit PF08597.10 EGC29309.1 - 0.34 10.8 9.7 0.5 10.2 9.7 1.2 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Exonuc_VII_L PF02601.15 EGC29309.1 - 1.1 8.7 17.2 1.7 8.1 17.2 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Merozoite_SPAM PF07133.11 EGC29309.1 - 1.9 8.4 12.5 3 7.8 12.5 1.2 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Allantoicase PF03561.15 EGC29309.1 - 3.7 7.5 8.1 2.8 7.9 5.4 2.1 1 1 1 2 2 2 0 Allantoicase repeat O-antigen_lig PF13425.6 EGC29309.1 - 4.5 5.9 7.2 6.5 5.4 7.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Pex14_N PF04695.13 EGC29309.1 - 4.7 7.8 17.4 9.2 6.9 17.4 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S46 PF10459.9 EGC29309.1 - 4.8 5.7 11.6 6.4 5.3 11.6 1.1 1 0 0 1 1 1 0 Peptidase S46 Bud13 PF09736.9 EGC29309.1 - 5.9 7.3 15.7 10 6.5 15.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor of RES complex FUSC PF04632.12 EGC29309.1 - 7.2 5.0 7.0 9.6 4.6 7.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family FapA PF03961.13 EGC29309.1 - 9.3 4.7 11.4 13 4.3 11.4 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A SNARE_assoc PF09335.11 EGC29310.1 - 7.8e-29 100.6 3.9 7.8e-29 100.6 3.9 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein AdoHcyase PF05221.17 EGC29311.1 - 4.3e-136 452.9 0.0 6.7e-74 248.7 0.3 2.0 1 1 1 2 2 2 2 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.21 EGC29311.1 - 2.7e-83 277.9 4.7 4.5e-83 277.2 4.7 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.19 EGC29311.1 - 7.6e-06 25.4 0.1 1.5e-05 24.4 0.1 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGC29311.1 - 0.0035 16.9 0.5 0.006 16.2 0.5 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain TrkA_N PF02254.18 EGC29311.1 - 0.0097 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain LpxI_N PF17930.1 EGC29311.1 - 0.036 14.0 0.3 0.42 10.5 0.1 2.6 3 0 0 3 3 3 0 LpxI N-terminal domain NKAIN PF05640.14 EGC29311.1 - 0.058 12.6 0.2 0.1 11.8 0.2 1.4 1 0 0 1 1 1 0 Na,K-Atpase Interacting protein F420_oxidored PF03807.17 EGC29311.1 - 0.073 13.7 0.2 0.19 12.4 0.2 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.18 EGC29311.1 - 0.14 12.1 0.6 0.27 11.1 0.6 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDT PF02791.17 EGC29312.1 - 0.0038 17.5 0.0 0.0085 16.4 0.0 1.5 1 0 0 1 1 1 1 DDT domain Pur_ac_phosph_N PF16656.5 EGC29313.1 - 1.3e-20 73.8 1.7 1.3e-20 73.8 1.7 3.0 3 2 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGC29313.1 - 1.6e-20 74.5 0.7 3.1e-20 73.5 0.3 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGC29313.1 - 2.9e-17 63.3 0.1 9.5e-17 61.6 0.1 2.0 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGC29313.1 - 0.001 19.3 0.0 0.0027 17.9 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD_N PF16655.5 EGC29313.1 - 0.074 13.6 0.1 0.3 11.7 0.0 2.0 2 0 0 2 2 2 0 PhoD-like phosphatase, N-terminal domain PhoD PF09423.10 EGC29313.1 - 0.26 10.3 2.3 0.14 11.1 0.2 1.6 2 0 0 2 2 2 0 PhoD-like phosphatase NAD_binding_4 PF07993.12 EGC29314.1 - 2.5e-11 43.2 0.0 4.5e-11 42.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein DUF1140 PF06600.11 EGC29315.1 - 0.0074 16.7 1.7 0.0074 16.7 1.7 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1140) PX PF00787.24 EGC29315.1 - 0.53 10.3 5.8 0.38 10.8 3.2 1.9 1 1 1 2 2 2 0 PX domain HJURP_C PF12347.8 EGC29315.1 - 6.6 6.9 7.5 3.3 7.8 0.1 2.8 3 1 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat FNIP PF05725.12 EGC29316.1 - 3.2e-112 366.5 91.1 4e-15 55.7 0.5 14.4 6 4 5 14 14 14 14 FNIP Repeat SNARE PF05739.19 EGC29317.1 - 2e-11 43.7 4.3 4.9e-11 42.5 3.4 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EGC29317.1 - 0.00013 21.8 10.6 0.048 13.3 3.3 2.9 2 1 1 3 3 3 2 Syntaxin Syntaxin-6_N PF09177.11 EGC29317.1 - 0.27 11.8 6.5 1.3 9.7 2.0 2.9 2 1 0 2 2 2 0 Syntaxin 6, N-terminal T2SSF PF00482.23 EGC29317.1 - 0.6 10.1 4.3 3.7 7.5 0.2 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F Syntaxin-18_N PF10496.9 EGC29317.1 - 3.6 7.9 13.6 0.18 12.1 0.6 3.6 2 2 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1664 PF07889.12 EGC29317.1 - 7.1 6.7 7.2 5.4 7.1 0.7 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) ACOX PF01756.19 EGC29318.1 - 1.4e-24 86.7 0.2 5.4e-24 84.7 0.0 2.1 3 0 0 3 3 3 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGC29318.1 - 2.6e-13 50.0 0.0 4e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC29318.1 - 8.2e-08 32.6 0.0 1.7e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGC29318.1 - 2.4e-07 31.3 0.0 6.9e-07 29.9 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.16 EGC29318.1 - 0.013 16.1 0.0 0.031 14.9 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain Epimerase PF01370.21 EGC29320.1 - 3.6e-19 69.2 0.0 5.5e-19 68.6 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC29320.1 - 5.3e-19 68.3 0.0 6.6e-19 68.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGC29320.1 - 1.1e-16 60.8 0.0 4.7e-16 58.7 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.6 EGC29320.1 - 5.7e-10 39.4 0.0 7.5e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGC29320.1 - 7.5e-10 38.7 0.1 1e-09 38.3 0.1 1.1 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGC29320.1 - 1.4e-05 25.3 0.1 2.4e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NmrA PF05368.13 EGC29320.1 - 3.9e-05 23.3 0.2 0.00087 18.9 0.3 2.1 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGC29320.1 - 8.5e-05 21.8 0.5 0.00015 21.0 0.5 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EGC29320.1 - 0.00035 21.0 0.3 0.0024 18.3 0.1 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Ldh_1_N PF00056.23 EGC29320.1 - 0.024 14.7 0.2 0.056 13.5 0.2 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGC29320.1 - 0.036 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus KR PF08659.10 EGC29320.1 - 0.15 11.9 0.1 1.7 8.5 0.1 2.1 1 1 0 1 1 1 0 KR domain SpoU_methylase PF00588.19 EGC29321.1 - 4.7e-33 114.4 0.0 6.3e-33 113.9 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGC29321.1 - 2.7e-06 27.5 0.0 5e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.9 EGC29321.1 - 0.037 13.9 0.0 0.059 13.2 0.0 1.4 1 0 0 1 1 1 0 SAM-dependent RNA methyltransferase CAP PF00188.26 EGC29322.1 - 3.5e-09 37.5 6.2 6e-09 36.8 6.2 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DEAD PF00270.29 EGC29323.1 - 3.3e-37 128.0 0.1 1e-36 126.3 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC29323.1 - 9.9e-25 87.0 1.6 2.6e-24 85.7 0.3 2.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC29323.1 - 1.3e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGC29323.1 - 9.8e-05 21.8 0.1 0.00017 21.0 0.1 1.3 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.6 EGC29323.1 - 0.0075 16.0 0.0 0.012 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain AIRS PF00586.24 EGC29323.1 - 0.027 15.1 0.0 0.044 14.4 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, N-terminal domain Dynactin_p22 PF07426.11 EGC29324.1 - 3.2e-24 85.7 16.9 5.7e-21 75.1 15.7 2.1 2 0 0 2 2 2 2 Dynactin subunit p22 Holin_BhlA PF10960.8 EGC29324.1 - 0.036 14.0 0.3 0.036 14.0 0.3 3.3 3 1 1 4 4 4 0 BhlA holin family UPF0227 PF05728.12 EGC29324.1 - 0.044 13.7 0.5 0.084 12.8 0.4 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF1664 PF07889.12 EGC29324.1 - 0.051 13.6 6.7 1.6 8.8 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Uds1 PF15456.6 EGC29324.1 - 1.5 9.0 7.5 1.3 9.2 0.8 2.9 2 2 1 3 3 3 0 Up-regulated During Septation GATA PF00320.27 EGC29325.1 - 9.4e-15 53.9 4.3 9.4e-15 53.9 4.3 2.0 2 0 0 2 2 2 1 GATA zinc finger Tyrosinase PF00264.20 EGC29325.1 - 0.017 15.5 0.7 0.017 15.5 0.7 4.6 2 1 1 3 3 3 0 Common central domain of tyrosinase DZR PF12773.7 EGC29325.1 - 0.33 11.0 5.7 7.6 6.6 1.0 2.6 2 0 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.22 EGC29325.1 - 4.8 7.2 7.6 0.71 9.8 1.1 2.2 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Abhydrolase_1 PF00561.20 EGC29326.1 - 1.4e-07 31.4 0.1 2.6e-07 30.6 0.1 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC29326.1 - 9.3e-06 25.1 0.0 1.2e-05 24.7 0.0 1.4 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC29326.1 - 0.00099 19.8 0.0 0.0012 19.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Palm_thioest PF02089.15 EGC29326.1 - 0.0055 16.6 0.0 0.0068 16.3 0.0 1.3 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EGC29326.1 - 0.035 13.4 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PH PF00169.29 EGC29327.1 - 1.1e-09 38.7 2.2 3e-09 37.3 2.2 1.8 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EGC29327.1 - 8.8e-07 29.0 3.0 2.1e-06 27.8 3.0 1.6 1 0 0 1 1 1 1 PH domain Myosin_TH1 PF06017.13 EGC29327.1 - 0.0024 17.6 0.1 0.0061 16.3 0.1 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding TraV PF09676.10 EGC29327.1 - 0.0059 17.6 2.7 0.0059 17.6 0.1 2.2 2 0 0 2 2 2 1 Type IV conjugative transfer system lipoprotein (TraV) ENOD93 PF03386.14 EGC29328.1 - 0.019 14.8 0.0 0.024 14.5 0.0 1.1 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein DUF1304 PF06993.12 EGC29328.1 - 0.025 14.6 0.0 0.031 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) DUF2076 PF09849.9 EGC29328.1 - 0.027 14.5 0.0 0.19 11.7 0.0 1.9 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF3899 PF13038.6 EGC29328.1 - 0.045 14.3 0.1 0.22 12.0 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) Tmemb_185A PF10269.9 EGC29329.1 - 6.6e-11 42.4 25.5 1.4e-06 28.2 4.6 3.1 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein DUF5399 PF17377.2 EGC29329.1 - 0.12 12.2 2.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5399) CrgA PF06781.12 EGC29329.1 - 5.4 7.1 8.8 0.26 11.4 0.5 2.9 2 1 1 3 3 3 0 Cell division protein CrgA DUF846 PF05832.12 EGC29330.1 - 3.3e-52 176.2 15.8 4.1e-52 175.9 15.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF5392 PF17370.2 EGC29330.1 - 0.11 12.5 0.2 0.11 12.5 0.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5392) DUF5592 PF17332.2 EGC29330.1 - 1.7 9.2 8.2 12 6.5 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5592) DUF3267 PF11667.8 EGC29330.1 - 5.1 7.4 15.3 9 6.6 2.4 2.2 2 0 0 2 2 2 0 Putative zincin peptidase AMP-binding PF00501.28 EGC29331.1 - 2.1e-74 250.6 0.0 2.7e-74 250.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC29331.1 - 4.3e-21 75.7 0.0 8.7e-21 74.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain HATPase_c PF02518.26 EGC29332.1 - 5.2e-25 88.1 1.7 5.6e-25 88.0 0.1 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC29332.1 - 8.3e-20 71.0 0.0 2.2e-19 69.7 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGC29332.1 - 1.1e-17 63.8 0.0 2.7e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGC29332.1 - 0.0017 18.6 0.3 0.0017 18.6 0.3 2.5 2 0 0 2 2 2 1 PAS domain PAS PF00989.25 EGC29332.1 - 0.12 12.4 0.7 1.3 9.1 0.0 2.8 2 1 0 2 2 2 0 PAS fold HATPase_c_3 PF13589.6 EGC29332.1 - 0.18 11.7 0.0 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Cdh1_DBD_1 PF18196.1 EGC29332.1 - 1.1 9.6 11.2 0.036 14.4 4.9 1.8 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 DUF4834 PF16118.5 EGC29333.1 - 3.7 8.6 9.8 7 7.7 0.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4783 PF16022.5 EGC29334.1 - 0.047 13.9 0.0 0.072 13.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) DUF4050 PF13259.6 EGC29334.1 - 0.07 13.4 0.0 0.07 13.4 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4050) PNTB PF02233.16 EGC29335.1 - 2.5e-173 577.2 12.3 2.5e-173 577.2 12.3 2.2 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.21 EGC29335.1 - 5.3e-75 251.4 0.3 1.6e-74 249.8 0.2 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.15 EGC29335.1 - 8.1e-45 152.5 0.4 1.7e-44 151.4 0.4 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain PNTB_4TM PF12769.7 EGC29335.1 - 2.9e-31 107.7 4.4 2.9e-31 107.7 4.4 3.9 3 1 1 4 4 4 1 4TM region of pyridine nucleotide transhydrogenase, mitoch 2-Hacid_dh_C PF02826.19 EGC29335.1 - 0.00034 20.0 1.1 0.46 9.8 0.1 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Pyr_redox_2 PF07992.14 EGC29335.1 - 0.039 13.2 0.2 0.085 12.1 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGC29335.1 - 0.089 13.2 0.2 5.1 7.6 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding TPP_enzyme_M PF00205.22 EGC29335.1 - 0.098 12.4 0.0 18 5.1 0.0 2.7 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TIG PF01833.24 EGC29336.1 - 3.1e-07 30.4 22.4 7.1e-05 22.8 0.9 5.1 4 1 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 EGC29336.1 - 0.00026 21.3 58.2 0.058 13.8 13.5 3.9 3 1 1 4 4 4 3 EGF-like domain Laminin_EGF PF00053.24 EGC29336.1 - 0.64 10.2 39.1 0.77 10.0 7.6 3.8 2 1 1 3 3 3 0 Laminin EGF domain FKBP_C PF00254.28 EGC29337.1 - 5.5e-11 42.6 0.0 1.9e-10 40.9 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Hen1_Lam_C PF18441.1 EGC29337.1 - 0.077 12.8 0.0 0.3 10.9 0.0 2.0 2 0 0 2 2 2 0 Hen1 La-motif C-terminal domain Act-Frag_cataly PF09192.10 EGC29338.1 - 7.1e-83 278.2 16.3 7.1e-83 278.2 16.3 1.6 1 1 0 1 1 1 1 Actin-fragmin kinase, catalytic TSP_NTD PF17804.1 EGC29338.1 - 0.014 15.7 0.2 0.014 15.7 0.2 2.7 3 0 0 3 3 3 0 Tail specific protease N-terminal domain SR-25 PF10500.9 EGC29338.1 - 1.6 8.3 14.8 3.4 7.2 14.8 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP PF00230.20 EGC29340.1 - 2.2e-49 168.2 19.6 7.1e-34 117.5 7.9 2.0 2 0 0 2 2 2 2 Major intrinsic protein zf-CCHC PF00098.23 EGC29341.1 - 0.0045 17.0 2.5 0.0076 16.3 2.5 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EGC29341.1 - 0.3 10.8 2.2 0.59 9.9 2.2 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EGC29341.1 - 0.97 9.3 4.3 1.7 8.5 4.3 1.4 1 0 0 1 1 1 0 Zinc knuckle Med4 PF10018.9 EGC29342.1 - 6.6e-33 114.0 2.2 6.6e-33 114.0 2.2 2.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Fungal_trans_2 PF11951.8 EGC29342.1 - 0.033 13.0 4.9 0.046 12.5 4.9 1.2 1 0 0 1 1 1 0 Fungal specific transcription factor domain TSA PF03249.13 EGC29342.1 - 0.56 8.9 8.9 0.79 8.4 8.9 1.2 1 0 0 1 1 1 0 Type specific antigen TFB6 PF17110.5 EGC29342.1 - 2.2 8.0 9.1 1 9.0 3.7 2.4 2 0 0 2 2 2 0 Subunit 11 of the general transcription factor TFIIH ORC_WH_C PF18137.1 EGC29342.1 - 2.6 8.1 11.2 0.42 10.7 5.4 2.5 3 1 0 3 3 3 0 Origin recognition complex winged helix C-terminal FAM76 PF16046.5 EGC29342.1 - 2.7 7.3 16.3 4.1 6.7 16.3 1.2 1 0 0 1 1 1 0 FAM76 protein Het-C PF07217.11 EGC29342.1 - 3.5 6.1 12.7 4.5 5.7 12.7 1.1 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C MDM10 PF12519.8 EGC29342.1 - 3.8 6.3 9.8 5.8 5.7 9.8 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 CLN3 PF02487.17 EGC29342.1 - 9.9 5.1 6.4 17 4.3 6.4 1.3 1 0 0 1 1 1 0 CLN3 protein DUF498 PF04430.14 EGC29343.1 - 4.5e-28 97.5 0.0 7e-28 96.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) YchF-GTPase_C PF06071.13 EGC29344.1 - 1.5e-34 118.0 0.1 3.8e-34 116.7 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGC29344.1 - 8.6e-23 80.6 0.3 2.4e-22 79.2 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC29344.1 - 1.2e-07 31.4 0.0 2.6e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B MeaB PF03308.16 EGC29344.1 - 0.0045 16.0 0.0 0.0079 15.2 0.0 1.3 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB Dynamin_N PF00350.23 EGC29344.1 - 0.23 11.5 1.2 11 6.0 0.1 2.7 1 1 2 3 3 3 0 Dynamin family Pkinase PF00069.25 EGC29345.1 - 2.9e-72 243.2 0.0 6.7e-72 242.0 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29345.1 - 1.8e-49 168.4 0.0 2.6e-49 167.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.8 EGC29345.1 - 5.4e-07 29.2 0.5 2.1e-06 27.3 0.3 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3543) MIT PF04212.18 EGC29345.1 - 6.9e-07 29.2 1.2 3.5e-05 23.8 1.6 2.4 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain Pkinase_fungal PF17667.1 EGC29345.1 - 0.0035 16.2 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGC29345.1 - 0.0093 15.9 0.0 0.034 14.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGC29345.1 - 0.018 14.4 0.0 0.035 13.4 0.0 1.5 1 1 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGC29345.1 - 0.12 11.8 0.0 0.32 10.3 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_9 PF14580.6 EGC29346.1 - 3.2e-11 43.1 0.4 7.8e-11 41.8 0.3 1.7 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.6 EGC29346.1 - 1.4e-05 24.7 0.4 1.4e-05 24.7 0.4 2.2 3 0 0 3 3 3 1 Leucine rich repeat DTHCT PF08070.11 EGC29346.1 - 0.044 14.5 26.8 0.058 14.1 9.0 2.7 1 1 1 2 2 2 0 DTHCT (NUC029) region LRR_4 PF12799.7 EGC29346.1 - 0.093 13.2 8.1 0.28 11.7 1.1 3.3 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) DUF3861 PF12977.7 EGC29346.1 - 0.11 12.7 1.1 0.23 11.7 0.1 2.1 2 0 0 2 2 2 0 Domain of Unknown Function with PDB structure (DUF3861) LRR_1 PF00560.33 EGC29346.1 - 1 10.1 3.4 5.4 8.0 0.1 3.3 3 0 0 3 3 3 0 Leucine Rich Repeat Hid1 PF12722.7 EGC29347.1 - 0.039 12.1 3.5 0.051 11.7 3.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RNA_pol_Rpb1_5 PF04998.17 EGC29348.1 - 4.8e-92 308.2 0.6 5.6e-91 304.7 0.6 2.3 1 1 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGC29348.1 - 5.6e-63 212.1 0.0 1.2e-62 211.0 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGC29348.1 - 6.3e-33 113.9 0.0 1.9e-32 112.4 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.12 EGC29348.1 - 3.3e-31 108.8 1.1 3.3e-31 108.8 1.1 3.2 2 2 1 3 3 3 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.17 EGC29348.1 - 1.1e-21 76.8 0.0 1.1e-21 76.8 0.0 3.3 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 SDA1 PF05285.12 EGC29348.1 - 0.062 12.7 37.1 0.091 12.2 27.6 2.4 2 0 0 2 2 2 0 SDA1 BUD22 PF09073.10 EGC29348.1 - 3.6 6.8 37.7 3.9 6.7 27.8 2.2 2 0 0 2 2 2 0 BUD22 NAF PF03822.14 EGC29349.1 - 0.89 9.8 4.1 14 6.0 0.1 3.2 4 0 0 4 4 4 0 NAF domain KCNQ2_u3 PF16642.5 EGC29350.1 - 0.71 10.9 6.7 0.15 13.1 2.1 2.1 1 1 1 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 Mito_fiss_reg PF05308.11 EGC29350.1 - 0.92 9.5 10.0 1.4 8.9 10.0 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Presenilin PF01080.17 EGC29350.1 - 1.5 7.5 6.2 1.9 7.2 6.2 1.1 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EGC29352.1 - 8 5.7 9.0 0.14 11.5 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) HMG_CoA_synt_N PF01154.17 EGC29353.1 - 3.2e-89 297.4 0.8 4.9e-89 296.8 0.8 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.10 EGC29353.1 - 1.2e-85 287.6 4.8 1.5e-85 287.2 4.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF3318 PF11780.8 EGC29354.1 - 0.16 11.9 0.0 0.22 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3318) Plasmodium_HRP PF05403.11 EGC29355.1 - 2.4 7.9 29.8 0.05 13.4 21.7 1.9 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) Q_salvage PF10343.9 EGC29356.1 - 4.2e-35 121.7 0.0 9.2e-35 120.6 0.0 1.5 1 1 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1084 PF06454.11 EGC29357.1 - 0.00041 19.8 15.3 0.00065 19.2 15.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.13 EGC29357.1 - 0.06 13.7 15.3 0.11 12.9 15.3 1.4 1 0 0 1 1 1 0 EGF-like domain DUF3611 PF12263.8 EGC29357.1 - 3.1 7.7 7.5 0.45 10.4 0.3 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF3611) EGF_Tenascin PF18720.1 EGC29357.1 - 3.7 7.7 6.4 8 6.6 6.4 1.5 1 0 0 1 1 1 0 Tenascin EGF domain I-EGF_1 PF18372.1 EGC29357.1 - 5.5 7.2 12.1 15 5.8 12.1 1.7 1 0 0 1 1 1 0 Integrin beta epidermal growth factor like domain 1 NTP_transf_2 PF01909.23 EGC29358.1 - 2.7e-09 37.2 0.1 1.6e-08 34.7 0.1 2.4 1 1 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGC29358.1 - 2.3e-06 27.7 0.2 2.3e-06 27.7 0.2 2.6 3 0 0 3 3 3 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGC29358.1 - 0.001 19.1 0.2 0.0038 17.3 0.2 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase FNIP PF05725.12 EGC29359.1 - 6.8e-68 224.6 44.9 1.5e-11 44.2 0.0 12.9 8 1 6 14 14 14 13 FNIP Repeat LRR_8 PF13855.6 EGC29359.1 - 0.081 12.7 0.1 0.081 12.7 0.1 5.1 6 2 1 7 7 7 0 Leucine rich repeat LRR_4 PF12799.7 EGC29359.1 - 3 8.4 28.5 6.4 7.4 4.3 7.6 3 2 5 8 8 8 0 Leucine Rich repeats (2 copies) Beach PF02138.18 EGC29360.1 - 2.9e-122 407.4 0.5 7.5e-122 406.0 0.5 1.8 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.6 EGC29360.1 - 1.1e-16 60.8 0.0 6.6e-16 58.2 0.0 2.6 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.32 EGC29360.1 - 6.8e-08 33.1 16.5 0.007 17.2 1.4 6.9 6 0 0 6 6 6 3 WD domain, G-beta repeat GRAM PF02893.20 EGC29360.1 - 0.0095 15.8 1.0 0.11 12.4 0.1 3.4 2 1 0 2 2 2 1 GRAM domain TIG PF01833.24 EGC29361.1 - 1.2e-19 70.2 33.9 2.2e-06 27.6 0.7 6.7 5 2 2 7 7 7 5 IPT/TIG domain DUF4448 PF14610.6 EGC29361.1 - 0.003 17.4 0.0 0.01 15.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) YabP PF07873.11 EGC29361.1 - 0.15 11.9 0.2 31 4.4 0.0 3.1 3 0 0 3 3 3 0 YabP family CBM_20 PF00686.19 EGC29362.1 - 3.4e-19 68.6 2.2 5.8e-19 67.8 1.9 1.6 1 1 1 2 2 2 1 Starch binding domain Pkinase PF00069.25 EGC29363.1 - 3.4e-11 43.0 0.1 3.4e-11 43.0 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29363.1 - 0.00091 18.6 0.0 0.0016 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HA PF03457.14 EGC29365.1 - 0.18 12.1 6.9 0.19 12.1 1.8 2.9 1 1 2 3 3 3 0 Helicase associated domain Fez1 PF06818.15 EGC29365.1 - 0.28 11.6 40.5 0.59 10.6 12.3 2.0 1 1 1 2 2 2 0 Fez1 TACC_C PF05010.14 EGC29365.1 - 1.8 8.3 41.9 0.019 14.8 31.6 2.0 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF2894 PF11445.8 EGC29365.1 - 2.8 8.4 12.0 2.2 8.7 9.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2894) DUF3584 PF12128.8 EGC29365.1 - 5.9 4.3 35.0 7.6 3.9 35.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) ERM PF00769.19 EGC29365.1 - 8.3 6.1 45.4 83 2.9 45.5 1.9 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF812 PF05667.11 EGC29365.1 - 8.6 5.1 41.2 11 4.7 41.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Melibiase_2 PF16499.5 EGC29366.1 - 8.8e-98 327.0 4.1 1.2e-97 326.6 4.1 1.1 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGC29366.1 - 2.2e-18 66.1 0.1 5.5e-18 64.8 0.1 1.7 1 0 0 1 1 1 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EGC29366.1 - 9.5e-12 45.0 0.0 1.8e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EGC29366.1 - 5.6e-06 25.5 0.0 1.1e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Melibiase ACT_4 PF13291.6 EGC29366.1 - 0.075 13.6 0.2 0.15 12.7 0.2 1.4 1 0 0 1 1 1 0 ACT domain Vps52 PF04129.12 EGC29367.1 - 1.2e-70 238.8 28.9 4.1e-70 237.0 28.9 1.8 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.9 EGC29367.1 - 5.2e-05 21.9 22.8 5.2e-05 21.9 22.8 2.8 1 1 1 2 2 2 1 Exocyst complex component Sec3 DUF72 PF01904.18 EGC29367.1 - 0.027 14.6 0.2 0.071 13.2 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function DUF72 DUF641 PF04859.12 EGC29367.1 - 0.052 13.9 5.7 0.23 11.8 0.8 3.4 3 0 0 3 3 3 0 Plant protein of unknown function (DUF641) Cep57_MT_bd PF06657.13 EGC29367.1 - 0.3 11.6 2.8 25 5.4 0.3 2.9 2 0 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 XhlA PF10779.9 EGC29367.1 - 0.39 11.0 4.6 0.57 10.4 0.1 3.5 3 0 0 3 3 3 0 Haemolysin XhlA FlbD PF06289.11 EGC29367.1 - 0.55 9.9 2.8 12 5.6 0.1 2.8 2 0 0 2 2 2 0 Flagellar and Swarming motility proteins DUF489 PF04356.12 EGC29367.1 - 1.5 8.8 8.2 0.2 11.6 1.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF489) Tmemb_185A PF10269.9 EGC29368.1 - 5.5e-49 167.1 12.9 5.5e-49 167.1 12.9 1.6 1 1 1 2 2 2 1 Transmembrane Fragile-X-F protein DnaJ PF00226.31 EGC29368.1 - 2.4e-26 91.7 1.2 3.8e-26 91.0 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF3671 PF12420.8 EGC29368.1 - 0.014 15.5 1.0 0.014 15.5 1.0 3.4 2 1 1 3 3 3 0 Protein of unknown function MFS_1 PF07690.16 EGC29368.1 - 1.2 8.0 29.1 0.38 9.6 4.9 2.4 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF1128 PF06569.11 EGC29369.1 - 0.057 13.4 0.4 0.12 12.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1128) CDC45 PF02724.14 EGC29371.1 - 0.00086 17.7 13.7 0.00086 17.7 13.7 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EGC29371.1 - 0.0032 16.9 23.8 0.0037 16.7 23.8 1.1 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EGC29371.1 - 0.0058 14.9 27.0 0.0067 14.7 27.0 1.1 1 0 0 1 1 1 1 Nop14-like family Mpp10 PF04006.12 EGC29371.1 - 0.0062 15.0 30.6 0.0078 14.7 30.6 1.1 1 0 0 1 1 1 1 Mpp10 protein BUD22 PF09073.10 EGC29371.1 - 0.01 15.2 18.4 0.011 15.2 18.4 1.1 1 0 0 1 1 1 0 BUD22 CPSF100_C PF13299.6 EGC29371.1 - 0.013 15.7 10.3 0.034 14.3 10.3 1.6 2 0 0 2 2 1 0 Cleavage and polyadenylation factor 2 C-terminal PCNA_N PF00705.18 EGC29371.1 - 0.023 14.4 0.4 0.096 12.4 0.1 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain SpoIIP PF07454.11 EGC29371.1 - 0.041 13.3 10.6 0.057 12.9 10.6 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Tim54 PF11711.8 EGC29371.1 - 0.041 12.7 9.8 0.055 12.3 9.8 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RR_TM4-6 PF06459.12 EGC29371.1 - 0.045 13.6 17.0 0.058 13.2 17.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.17 EGC29371.1 - 0.046 13.9 2.0 0.048 13.8 2.0 1.2 1 0 0 1 1 1 0 DDHD domain DUF913 PF06025.12 EGC29371.1 - 0.06 12.3 4.2 0.063 12.3 4.2 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGC29371.1 - 0.061 12.1 7.0 0.063 12.0 7.0 1.1 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGC29371.1 - 0.065 13.0 5.7 0.096 12.4 5.7 1.4 1 0 0 1 1 1 0 Connexin ESM4 PF15952.5 EGC29371.1 - 0.09 13.2 5.9 0.12 12.8 5.9 1.3 1 0 0 1 1 1 0 Enhancer of split M4 family Zip PF02535.22 EGC29371.1 - 0.29 10.3 5.0 0.31 10.2 5.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.16 EGC29371.1 - 0.3 11.1 3.8 0.37 10.8 3.8 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AAA_11 PF13086.6 EGC29371.1 - 0.34 10.7 8.4 0.42 10.3 8.4 1.2 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.12 EGC29371.1 - 0.4 9.9 22.0 0.61 9.3 22.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF3405 PF11885.8 EGC29371.1 - 0.51 8.9 8.5 0.66 8.5 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3405) DUF4045 PF13254.6 EGC29371.1 - 0.63 9.6 10.7 0.71 9.4 10.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Band_3_cyto PF07565.13 EGC29371.1 - 0.74 9.6 6.1 1 9.1 6.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TRAP_alpha PF03896.16 EGC29371.1 - 0.75 8.9 16.0 1.2 8.2 16.0 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RNA_pol_Rpc4 PF05132.14 EGC29371.1 - 0.8 10.1 9.0 1.2 9.5 9.0 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 EGC29371.1 - 0.83 9.0 22.9 1.3 8.4 22.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) SLC12 PF03522.15 EGC29371.1 - 0.93 8.4 7.6 1.1 8.2 7.6 1.2 1 0 0 1 1 1 0 Solute carrier family 12 DUF3391 PF11871.8 EGC29371.1 - 1.2 9.7 10.7 2.2 8.8 10.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) ALMT PF11744.8 EGC29371.1 - 1.4 7.6 5.3 1.6 7.5 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3306 PF11748.8 EGC29371.1 - 2 9.3 13.9 3.9 8.4 13.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) SNAPc_SNAP43 PF09808.9 EGC29371.1 - 2 8.3 9.4 1.7 8.5 7.7 1.8 2 1 0 2 2 2 0 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 RRN3 PF05327.11 EGC29371.1 - 2.6 6.5 16.1 3.4 6.1 16.1 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RPN2_C PF18004.1 EGC29371.1 - 3 7.8 20.2 5.1 7.0 20.2 1.4 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain LAP1C PF05609.12 EGC29371.1 - 3.1 6.8 15.1 3.7 6.5 15.1 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CDC27 PF09507.10 EGC29371.1 - 3.2 7.0 21.8 4.1 6.7 21.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 TFB6 PF17110.5 EGC29371.1 - 3.6 7.3 12.5 6.8 6.4 12.5 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH Nop53 PF07767.11 EGC29371.1 - 4 6.7 26.5 5.5 6.3 26.5 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) DUF2722 PF10846.8 EGC29371.1 - 5.6 5.8 13.1 7.4 5.4 13.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) CLN3 PF02487.17 EGC29371.1 - 5.8 5.9 5.5 7.4 5.5 5.5 1.2 1 0 0 1 1 1 0 CLN3 protein Sporozoite_P67 PF05642.11 EGC29371.1 - 6 4.8 12.7 9.8 4.1 12.7 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen V_ATPase_I PF01496.19 EGC29371.1 - 7.5 4.3 11.2 9.1 4.1 11.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2457 PF10446.9 EGC29371.1 - 7.7 5.5 30.6 10 5.2 30.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) AIF_C PF14721.6 EGC29371.1 - 8.5 6.7 8.3 17 5.8 8.3 1.7 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4820 PF16091.5 EGC29371.1 - 9.1 5.6 14.0 13 5.0 14.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ribosomal_S15 PF00312.22 EGC29372.1 - 0.036 14.3 0.1 0.4 10.9 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein S15 rve PF00665.26 EGC29372.1 - 0.1 12.8 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Integrase core domain THB PF18362.1 EGC29372.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 Tri-helix bundle domain Resolvase PF00239.21 EGC29373.1 - 6.4e-07 29.6 0.0 9e-06 25.9 0.0 2.6 2 0 0 2 2 2 1 Resolvase, N terminal domain Mucin PF01456.17 EGC29373.1 - 5.6 7.0 24.5 11 5.9 24.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_transf_10 PF00852.19 EGC29375.1 - 3.7e-14 52.8 2.1 1.2e-13 51.2 2.1 1.6 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term DUF2481 PF10654.9 EGC29375.1 - 0.029 14.4 0.7 0.036 14.1 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2481) Clr2_transil PF16761.5 EGC29375.1 - 0.06 14.2 1.8 0.12 13.2 1.8 1.8 1 1 0 1 1 1 0 Transcription-silencing protein, cryptic loci regulator Clr2 DUF4179 PF13786.6 EGC29377.1 - 2.7 8.5 8.9 9.1 6.8 8.9 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4179) RasGAP PF00616.19 EGC29378.1 - 2e-53 181.2 4.3 2e-53 181.2 4.3 3.0 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGC29378.1 - 1.2e-16 61.1 5.9 1.2e-16 61.1 5.9 2.9 2 0 0 2 2 2 1 RasGAP C-terminus zf-TFIIIC PF12660.7 EGC29381.1 - 3.9e-06 26.7 6.5 4.1e-06 26.7 5.6 1.5 1 1 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex DZR PF12773.7 EGC29381.1 - 0.062 13.3 9.5 39 4.4 9.5 3.3 1 1 0 1 1 1 0 Double zinc ribbon zf-CHCC PF10276.9 EGC29381.1 - 0.2 11.7 4.0 9.6 6.4 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger domain zinc-ribbons_6 PF07191.12 EGC29381.1 - 1.4 9.0 8.4 0.33 11.0 3.0 2.6 2 1 1 3 3 3 0 zinc-ribbons Cytochrome_C7 PF14522.6 EGC29381.1 - 1.4 9.0 5.4 7.1 6.7 5.4 2.2 1 1 0 1 1 1 0 Cytochrome c7 and related cytochrome c zf-C2HC5 PF06221.13 EGC29381.1 - 1.4 8.9 8.9 2.3 8.3 0.2 3.7 2 1 2 4 4 4 0 Putative zinc finger motif, C2HC5-type zf-C3HC4_3 PF13920.6 EGC29381.1 - 4.6 7.2 11.2 17 5.3 0.0 3.5 2 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) PyrI_C PF02748.15 EGC29381.1 - 6.5 6.8 17.6 1.7 8.6 4.4 3.6 4 0 0 4 4 4 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain TPR_2 PF07719.17 EGC29382.1 - 1.8e-14 52.6 5.2 6.1e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGC29382.1 - 6.7e-13 47.9 8.4 0.00017 21.3 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-C3HC4 PF00097.25 EGC29382.1 - 1.5e-07 31.2 14.3 1.5e-07 31.2 14.3 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.6 EGC29382.1 - 6.3e-07 29.0 5.9 0.011 15.4 0.8 3.5 2 1 1 3 3 3 3 TPR repeat zf-C3HC4_2 PF13923.6 EGC29382.1 - 8.8e-07 28.7 15.1 8.8e-07 28.7 15.1 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC29382.1 - 1.2e-06 28.3 10.1 2.8e-06 27.1 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_17 PF13431.6 EGC29382.1 - 2.4e-06 27.5 6.8 0.026 14.9 0.1 4.0 3 1 1 4 4 3 2 Tetratricopeptide repeat zf-RING_5 PF14634.6 EGC29382.1 - 9.4e-06 25.5 14.0 2.5e-05 24.1 14.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain TPR_8 PF13181.6 EGC29382.1 - 1.2e-05 25.1 7.8 0.012 15.8 0.1 3.7 4 0 0 4 4 3 2 Tetratricopeptide repeat zf-RING_2 PF13639.6 EGC29382.1 - 2.3e-05 24.6 14.2 5.6e-05 23.4 14.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC29382.1 - 2.7e-05 24.1 9.6 2.7e-05 24.1 9.6 2.2 1 1 0 1 1 1 1 RING-type zinc-finger ANAPC3 PF12895.7 EGC29382.1 - 2.8e-05 24.3 4.1 5.1e-05 23.4 4.1 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGC29382.1 - 0.00054 20.2 1.8 0.049 13.9 0.4 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC29382.1 - 0.0012 19.3 0.0 0.19 12.3 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC29382.1 - 0.0013 19.4 0.0 0.0058 17.2 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-RING_6 PF14835.6 EGC29382.1 - 0.004 17.0 9.2 0.0086 15.9 9.2 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGC29382.1 - 0.0068 16.5 15.8 0.014 15.5 15.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING NARP1 PF12569.8 EGC29382.1 - 0.014 14.4 0.2 0.027 13.4 0.1 1.4 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 TPR_6 PF13174.6 EGC29382.1 - 0.019 15.6 1.2 2.2 9.1 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat PBAN PF05874.11 EGC29382.1 - 0.03 14.2 0.2 0.044 13.7 0.2 1.3 1 0 0 1 1 1 0 Pheromone biosynthesis activating neuropeptide (PBAN) TPR_9 PF13371.6 EGC29382.1 - 0.059 13.5 0.2 0.11 12.6 0.2 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Prok-RING_4 PF14447.6 EGC29382.1 - 0.068 13.1 16.0 4.4 7.3 16.5 2.6 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 TPR_14 PF13428.6 EGC29382.1 - 0.076 13.9 0.1 2.9 9.0 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.9 EGC29382.1 - 0.094 11.4 0.5 0.15 10.8 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) zf-RING_4 PF14570.6 EGC29382.1 - 0.17 11.7 11.9 0.54 10.1 11.9 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 EGC29382.1 - 2.2 8.8 7.9 11 6.6 0.5 3.3 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Menin PF05053.13 EGC29382.1 - 4.9 5.4 13.1 7.6 4.8 13.1 1.2 1 0 0 1 1 1 0 Menin FSA_C PF10479.9 EGC29382.1 - 8.8 4.3 9.2 12 3.8 9.2 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus RhoGEF PF00621.20 EGC29383.1 - 7.1e-39 133.9 0.5 7.1e-39 133.9 0.5 3.5 3 2 0 3 3 3 1 RhoGEF domain IQ PF00612.27 EGC29383.1 - 0.00029 20.4 0.1 0.00057 19.4 0.1 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif IQ_SEC7_PH PF16453.5 EGC29383.1 - 0.0046 16.9 0.4 0.017 15.1 0.4 2.0 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 EGC29383.1 - 0.016 15.0 0.1 0.047 13.5 0.1 1.7 1 0 0 1 1 1 0 PH domain PH_10 PF15411.6 EGC29383.1 - 0.051 13.8 0.1 0.051 13.8 0.1 3.9 5 0 0 5 5 5 0 Pleckstrin homology domain zf-C2H2_4 PF13894.6 EGC29383.1 - 0.15 12.9 0.1 0.42 11.6 0.1 1.8 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2207 PF09972.9 EGC29384.1 - 0.00089 18.1 0.6 0.0015 17.4 0.6 1.4 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 EGC29384.1 - 0.0025 17.7 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Erf4 PF10256.9 EGC29385.1 - 1e-05 25.6 2.5 0.0001 22.4 1.1 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF5362 PF17319.2 EGC29385.1 - 0.0051 16.6 1.0 0.073 12.9 0.5 2.2 2 0 0 2 2 2 1 Family of unknown function (DUF5362) DUF2207 PF09972.9 EGC29385.1 - 0.021 13.6 3.7 0.028 13.2 3.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PA14 PF07691.12 EGC29386.1 - 1e-13 51.3 0.1 1.7e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC29386.1 - 3.6e-07 30.0 48.0 3.4e-05 23.7 8.3 39.4 36 6 5 41 41 41 17 Dictyostelium (slime mold) repeat SH3_19 PF18597.1 EGC29386.1 - 0.068 13.0 16.2 0.65 9.9 0.4 5.5 4 0 0 4 4 4 0 Myosin X N-terminal SH3 domain Sel1 PF08238.12 EGC29387.1 - 1.1e-08 35.4 0.4 0.06 14.1 0.0 4.5 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.17 EGC29387.1 - 2.7e-06 27.1 5.8 0.016 15.3 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC29387.1 - 0.00024 21.3 2.2 0.022 15.0 0.0 4.4 5 0 0 5 5 5 1 Tetratricopeptide repeat MIT PF04212.18 EGC29387.1 - 0.068 13.2 3.8 0.28 11.3 0.0 3.6 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain TPR_1 PF00515.28 EGC29387.1 - 0.073 12.9 14.0 0.56 10.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC29387.1 - 0.47 10.8 8.3 28 5.2 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF2203 PF09969.9 EGC29387.1 - 2.4 8.9 6.2 1.4 9.6 0.7 2.9 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2203) GATA PF00320.27 EGC29389.1 - 1.2e-16 60.0 5.5 2.6e-16 58.9 5.5 1.5 1 0 0 1 1 1 1 GATA zinc finger adh_short PF00106.25 EGC29391.1 - 5.2e-38 130.5 0.6 1e-37 129.5 0.6 1.4 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC29391.1 - 8.6e-35 120.4 0.0 2.5e-34 118.9 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC29391.1 - 8.8e-15 55.1 0.9 1.8e-13 50.8 0.9 2.0 1 1 0 1 1 1 1 KR domain 3Beta_HSD PF01073.19 EGC29391.1 - 0.00063 18.8 0.1 0.0076 15.3 0.1 2.0 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC29391.1 - 0.0021 17.6 0.1 0.0031 17.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EGC29391.1 - 0.0062 16.5 0.1 0.01 15.8 0.1 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PRP1_N PF06424.12 EGC29393.1 - 9.2e-45 152.7 7.9 9.2e-45 152.7 7.9 2.4 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.6 EGC29393.1 - 4e-31 105.0 9.2 0.013 16.3 0.0 13.4 4 4 11 15 15 15 9 Tetratricopeptide repeat TPR_19 PF14559.6 EGC29393.1 - 3.6e-25 88.2 3.6 8.4e-05 23.0 0.4 7.9 7 2 1 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGC29393.1 - 1.6e-09 37.4 8.1 0.23 11.9 0.1 9.4 11 1 1 12 12 12 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC29393.1 - 8.5e-09 34.9 6.4 2.9 8.3 0.1 10.1 11 0 0 11 11 11 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC29393.1 - 1.5e-06 27.8 9.1 6.2 7.2 0.0 9.8 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC29393.1 - 5.2e-05 23.8 1.0 2.2 9.0 0.0 4.7 4 0 0 4 4 4 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC29393.1 - 0.00022 21.4 0.4 4.3 7.6 0.1 4.8 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGC29393.1 - 0.0059 16.3 0.2 19 5.0 0.0 4.9 4 1 2 6 6 6 0 TPR repeat TPR_9 PF13371.6 EGC29393.1 - 0.051 13.7 0.1 24 5.2 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 EGC29393.1 - 0.13 12.3 0.5 38 4.4 0.1 3.3 4 0 0 4 4 3 0 Protein of unknown function (DUF627) POTRA_1 PF08478.10 EGC29393.1 - 0.37 11.1 3.8 8.3 6.8 0.7 3.6 3 0 0 3 3 3 0 POTRA domain, FtsQ-type DDE_Tnp_4 PF13359.6 EGC29395.1 - 1.2e-06 28.3 0.3 1.6e-06 27.9 0.3 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC29395.1 - 0.00039 20.1 0.0 0.00059 19.5 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain YjbH PF06082.11 EGC29395.1 - 0.039 12.8 0.1 0.38 9.5 0.1 1.8 1 1 1 2 2 2 0 Exopolysaccharide biosynthesis protein YbjH ER_lumen_recept PF00810.18 EGC29396.1 - 7.7e-54 182.5 11.2 1e-53 182.1 11.2 1.2 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.14 EGC29396.1 - 0.0055 16.5 12.4 0.033 14.0 0.9 3.5 2 1 2 4 4 4 2 PQ loop repeat VPS9 PF02204.18 EGC29397.1 - 1.4e-30 105.6 1.5 2e-30 105.0 0.1 2.1 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.24 EGC29397.1 - 6.7e-18 64.7 0.2 2e-17 63.2 0.2 1.9 1 0 0 1 1 1 1 PX domain Ras PF00071.22 EGC29397.1 - 3.5e-08 33.2 0.0 1.1e-07 31.5 0.0 1.9 1 0 0 1 1 1 1 Ras family DUF5601 PF18151.1 EGC29397.1 - 0.02 15.2 1.1 0.085 13.2 1.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5601) DMA PF03474.14 EGC29397.1 - 0.054 13.1 0.0 0.19 11.3 0.0 1.9 2 0 0 2 2 2 0 DMRTA motif Roc PF08477.13 EGC29397.1 - 0.14 12.4 3.4 0.1 12.9 0.4 2.4 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase B12-binding_2 PF02607.17 EGC29397.1 - 0.18 12.3 0.0 0.38 11.2 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain F-box_5 PF18511.1 EGC29398.1 - 0.028 14.0 2.1 0.85 9.2 0.7 3.1 3 0 0 3 3 3 0 F-box F-box-like PF12937.7 EGC29398.1 - 0.5 10.3 2.2 0.97 9.4 0.1 2.6 3 1 0 3 3 3 0 F-box-like Pkinase PF00069.25 EGC29399.1 - 2.7e-47 161.4 3.6 5.4e-47 160.4 0.1 2.7 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.12 EGC29399.1 - 8e-34 116.5 0.2 8e-34 116.5 0.2 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.17 EGC29399.1 - 1.5e-27 96.5 1.6 2.4e-27 95.9 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC29399.1 - 5.2e-08 32.5 1.2 6.1e-08 32.3 0.0 1.6 2 0 0 2 2 2 1 Kinase-like PQQ_2 PF13360.6 EGC29399.1 - 0.00041 20.0 0.0 0.11 12.1 0.0 2.5 1 1 0 2 2 2 1 PQQ-like domain EPL1 PF10513.9 EGC29399.1 - 0.0013 19.2 0.9 0.0013 19.2 0.9 3.5 2 2 1 3 3 1 1 Enhancer of polycomb-like DUF3899 PF13038.6 EGC29399.1 - 0.0043 17.5 2.8 0.011 16.2 0.1 3.2 3 0 0 3 3 3 1 Domain of unknown function (DUF3899) Pkinase_fungal PF17667.1 EGC29399.1 - 0.0067 15.3 0.0 0.0067 15.3 0.0 2.5 2 1 0 2 2 2 1 Fungal protein kinase SID-1_RNA_chan PF13965.6 EGC29399.1 - 0.1 11.0 10.9 0.075 11.4 9.3 1.5 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 MscL PF01741.18 EGC29399.1 - 0.15 12.4 4.0 0.072 13.4 1.3 1.9 2 0 0 2 2 1 0 Large-conductance mechanosensitive channel, MscL DUF4199 PF13858.6 EGC29399.1 - 0.19 12.1 3.1 14 6.0 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) APH PF01636.23 EGC29399.1 - 0.25 11.3 0.0 0.57 10.1 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family DHHC PF01529.20 EGC29399.1 - 0.3 11.2 1.8 4 7.6 0.3 2.5 2 0 0 2 2 2 0 DHHC palmitoyltransferase Neur_chan_memb PF02932.16 EGC29399.1 - 0.41 10.7 5.5 0.93 9.5 5.5 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TMEM51 PF15345.6 EGC29399.1 - 0.93 9.3 10.6 2 8.2 6.8 2.3 2 0 0 2 2 2 0 Transmembrane protein 51 O-antigen_lig PF13425.6 EGC29399.1 - 3.7 6.2 36.9 0.086 11.6 3.5 2.8 2 1 1 3 3 3 0 O-antigen ligase like membrane protein PepSY_TM_like_2 PF16357.5 EGC29399.1 - 3.8 7.5 5.9 0.58 10.1 1.8 1.7 2 0 0 2 2 1 0 Putative PepSY_TM-like Pannexin_like PF12534.8 EGC29400.1 - 5.9 5.9 11.8 5.5 6.0 9.7 1.9 2 0 0 2 2 2 0 Pannexin-like TM region of LRRC8 Peptidase_C37 PF05416.12 EGC29400.1 - 8.8 4.7 15.1 15 4.0 15.1 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase TMEM144 PF07857.12 EGC29401.1 - 6.1e-65 219.4 16.4 5.9e-64 216.1 16.4 1.9 1 1 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 EGC29401.1 - 9.8e-09 34.9 4.6 9.8e-09 34.9 4.6 2.9 2 2 0 2 2 2 1 Sugar transport protein Sec20 PF03908.13 EGC29402.1 - 9.3e-17 60.7 4.0 9.3e-17 60.7 4.0 3.0 2 1 2 4 4 4 1 Sec20 ThiD2 PF17792.1 EGC29402.1 - 0.014 15.9 3.8 0.014 15.9 3.8 2.0 1 1 2 3 3 3 0 ThiD2 family Tn7_TnsC_Int PF11426.8 EGC29402.1 - 0.081 13.1 1.8 6.7 7.0 0.0 2.7 2 0 0 2 2 2 0 Tn7 transposition regulator TnsC Thiamine_BP PF01910.17 EGC29402.1 - 0.098 12.6 0.0 0.28 11.1 0.0 1.7 2 0 0 2 2 2 0 Thiamine-binding protein LMBR1 PF04791.16 EGC29402.1 - 0.82 8.5 13.7 0.98 8.3 13.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein GAPT PF11770.8 EGC29402.1 - 1.3 8.9 10.6 0.33 10.8 4.2 2.4 1 1 0 2 2 2 0 GRB2-binding adapter (GAPT) AAA_33 PF13671.6 EGC29403.1 - 1.3e-05 25.3 0.0 4.7e-05 23.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain SWIM PF04434.17 EGC29403.1 - 0.00011 21.7 0.4 0.00028 20.5 0.4 1.7 1 0 0 1 1 1 1 SWIM zinc finger FliC PF12445.8 EGC29403.1 - 0.14 12.5 1.5 2.5 8.5 0.3 2.6 2 0 0 2 2 2 0 Flagellin protein Csd3_N PF18059.1 EGC29404.1 - 4 8.0 7.7 5.5 7.6 0.6 3.8 3 2 0 3 3 3 0 Csd3 N-terminal Cwf_Cwc_15 PF04889.12 EGC29406.1 - 0.0024 17.7 29.7 0.0024 17.7 29.7 2.6 2 1 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein NOA36 PF06524.12 EGC29406.1 - 0.0039 16.5 25.1 0.0039 16.5 25.1 2.5 2 1 1 3 3 3 1 NOA36 protein AIF_C PF14721.6 EGC29407.1 - 5.2 7.4 8.5 29 5.0 6.0 2.3 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term WD40_4 PF16300.5 EGC29408.1 - 1.1e-09 38.0 0.1 2e-09 37.2 0.1 1.5 1 1 0 1 1 1 1 Type of WD40 repeat SMRP1 PF15181.6 EGC29408.1 - 0.022 14.3 0.0 0.024 14.2 0.0 1.1 1 0 0 1 1 1 0 Spermatid-specific manchette-related protein 1 PLDc_N PF13396.6 EGC29409.1 - 1.9 8.5 5.8 2.8 7.9 5.8 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal FAM222A PF15258.6 EGC29409.1 - 2 7.5 19.0 2.1 7.3 19.0 1.1 1 0 0 1 1 1 0 Protein family of FAM222A TFIIA PF03153.13 EGC29409.1 - 2.6 7.9 29.1 3.3 7.6 29.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAT PF03417.16 EGC29412.1 - 0.08 12.6 0.0 0.085 12.5 0.0 1.0 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Macoilin PF09726.9 EGC29413.1 - 7.6 4.9 15.3 9.7 4.6 15.3 1.1 1 0 0 1 1 1 0 Macoilin family LAGLIDADG_1 PF00961.19 EGC29413.1 - 7.7 7.6 12.5 0.77 10.8 4.1 2.5 1 1 1 2 2 2 0 LAGLIDADG endonuclease AAA_23 PF13476.6 EGC29414.1 - 0.013 16.1 13.5 0.017 15.7 13.5 1.1 1 0 0 1 1 1 0 AAA domain PLDc_N PF13396.6 EGC29414.1 - 1.6 8.7 5.0 2.3 8.2 5.0 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal FeoB_associated PF12669.7 EGC29414.1 - 6.7 7.2 8.3 12 6.4 8.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein Nramp PF01566.18 EGC29415.1 - 3.6e-127 424.3 13.9 3.6e-127 424.3 13.9 1.7 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein FA_hydroxylase PF04116.13 EGC29416.1 - 6.1e-29 101.1 13.1 6.1e-29 101.1 13.1 2.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily Insulin_TMD PF17870.1 EGC29416.1 - 6.3 7.0 8.7 8.2 6.6 0.2 3.0 3 0 0 3 3 3 0 Insulin receptor trans-membrane segment Peptidase_M66 PF10462.9 EGC29419.1 - 8.4e-114 379.6 4.2 1.2e-113 379.1 4.2 1.2 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.8 EGC29419.1 - 0.0043 15.7 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Putative peptidase family OSTbeta PF15048.6 EGC29420.1 - 0.054 13.6 0.0 0.064 13.4 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Mem_trans PF03547.18 EGC29420.1 - 0.061 11.7 0.3 0.072 11.5 0.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Epiglycanin_C PF14654.6 EGC29420.1 - 0.1 12.7 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region Sulfate_transp PF00916.20 EGC29420.1 - 0.12 11.2 0.2 0.14 10.9 0.2 1.1 1 0 0 1 1 1 0 Sulfate permease family ATP-synt_8 PF00895.20 EGC29420.1 - 2.7 8.5 4.8 0.67 10.4 0.2 2.3 3 0 0 3 3 3 0 ATP synthase protein 8 DAO PF01266.24 EGC29421.1 - 2.3e-06 27.5 0.0 3.4e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC29421.1 - 0.00017 21.8 0.0 0.00087 19.5 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGC29421.1 - 0.00042 19.1 0.0 0.00072 18.4 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.24 EGC29421.1 - 0.00093 18.4 0.0 0.0013 17.9 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGC29421.1 - 0.0069 15.7 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGC29421.1 - 0.077 12.1 0.2 0.24 10.4 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A TSC22 PF01166.18 EGC29421.1 - 0.57 10.5 4.6 10 6.5 0.1 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family FidL_like PF15941.5 EGC29422.1 - 0.031 14.7 0.8 0.043 14.3 0.8 1.3 1 0 0 1 1 1 0 FidL-like putative membrane protein DUF3409 PF11889.8 EGC29424.1 - 0.096 12.6 0.2 0.23 11.4 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3409) TIG PF01833.24 EGC29426.1 - 0.00016 21.7 37.5 0.00058 19.9 1.9 6.5 5 1 1 6 6 6 3 IPT/TIG domain BcsB PF03170.13 EGC29426.1 - 0.19 10.1 0.9 2 6.7 0.1 2.2 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit Myco_arth_vir_N PF09610.10 EGC29426.1 - 0.51 10.5 4.0 12 6.1 1.2 2.8 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) NusA_N PF08529.11 EGC29427.1 - 0.13 12.6 0.5 0.25 11.7 0.5 1.7 1 1 0 1 1 1 0 NusA N-terminal domain SRP54 PF00448.22 EGC29428.1 - 5.8e-54 182.7 0.6 3.3e-53 180.2 0.6 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.13 EGC29428.1 - 3.3e-21 76.5 36.8 3.3e-16 60.1 0.3 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal SRP54_N PF02881.19 EGC29428.1 - 1.5e-06 28.3 0.0 1.5e-06 28.3 0.0 2.7 2 0 0 2 2 1 1 SRP54-type protein, helical bundle domain MeaB PF03308.16 EGC29428.1 - 8.8e-06 24.9 0.0 2e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CbiA PF01656.23 EGC29428.1 - 0.00011 22.2 1.0 0.034 14.2 0.0 2.6 2 0 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.19 EGC29428.1 - 0.00077 19.1 1.6 0.0072 15.9 1.6 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGC29428.1 - 0.0012 18.6 0.2 0.0039 16.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.15 EGC29428.1 - 0.0014 18.6 0.0 0.92 9.4 0.0 2.7 2 0 0 2 2 2 2 NTPase AAA_22 PF13401.6 EGC29428.1 - 0.0028 17.9 0.1 0.013 15.8 0.0 2.1 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.6 EGC29428.1 - 0.0033 17.8 0.0 0.011 16.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain ETF PF01012.21 EGC29428.1 - 0.016 15.1 0.2 0.041 13.8 0.2 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein domain AAA_33 PF13671.6 EGC29428.1 - 0.046 13.9 0.0 0.14 12.3 0.0 1.8 1 0 0 1 1 1 0 AAA domain VirC1 PF07015.11 EGC29428.1 - 0.053 12.8 0.1 0.096 12.0 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein RsgA_GTPase PF03193.16 EGC29428.1 - 0.16 11.9 3.6 10 6.0 1.9 3.8 2 2 1 3 3 3 0 RsgA GTPase SPOUT_MTase PF02590.17 EGC29428.1 - 0.35 10.8 0.0 0.35 10.8 0.0 2.5 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase La PF05383.17 EGC29429.1 - 3.4e-18 65.4 0.1 1.2e-17 63.7 0.1 2.0 1 0 0 1 1 1 1 La domain DHC_N1 PF08385.12 EGC29433.1 - 0.021 13.5 0.3 0.021 13.5 0.3 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 CFAP91 PF14738.6 EGC29433.1 - 0.069 13.2 2.1 0.073 13.1 2.1 1.0 1 0 0 1 1 1 0 Cilia- and flagella-associated protein 91 SAP PF02037.27 EGC29434.1 - 1.3e-06 27.9 0.0 5.4e-06 26.0 0.0 2.1 1 0 0 1 1 1 1 SAP domain Sema PF01403.19 EGC29434.1 - 0.047 12.5 0.9 0.58 8.9 0.2 2.4 3 0 0 3 3 3 0 Sema domain ACCA PF03255.14 EGC29434.1 - 0.27 11.1 2.3 1 9.3 1.9 2.3 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RhoGAP PF00620.27 EGC29435.1 - 5.3e-34 117.2 1.5 5.3e-34 117.2 1.5 3.0 2 0 0 2 2 2 1 RhoGAP domain DUF2992 PF11208.8 EGC29435.1 - 1.8 8.8 10.8 5.9 7.1 9.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Menin PF05053.13 EGC29436.1 - 8.3 4.6 13.8 11 4.3 13.8 1.1 1 0 0 1 1 1 0 Menin DDOST_48kD PF03345.14 EGC29437.1 - 2.2e-119 399.0 0.3 2.5e-119 398.8 0.3 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.6 EGC29437.1 - 0.012 16.1 0.0 0.12 12.8 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4350) RhoGAP PF00620.27 EGC29438.1 - 0.0083 16.0 3.9 0.08 12.8 0.7 2.8 2 0 0 2 2 2 2 RhoGAP domain Pkinase PF00069.25 EGC29439.1 - 2.6e-77 259.8 0.0 3.4e-77 259.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29439.1 - 2.1e-41 141.9 0.0 3.3e-41 141.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase AdenylateSensor PF16579.5 EGC29439.1 - 3.8e-08 33.8 0.1 1.1e-06 29.1 0.1 2.8 2 1 0 2 2 2 1 Adenylate sensor of SNF1-like protein kinase Kinase-like PF14531.6 EGC29439.1 - 5.8e-07 29.1 0.0 9.6e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like KA1 PF02149.19 EGC29439.1 - 1.1e-05 25.1 0.3 3e-05 23.7 0.3 1.8 1 0 0 1 1 1 1 Kinase associated domain 1 RIO1 PF01163.22 EGC29439.1 - 0.00072 19.2 1.3 0.0012 18.5 1.3 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGC29439.1 - 0.016 15.1 0.1 0.99 9.3 0.5 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family NAP PF00956.18 EGC29440.1 - 2.1e-11 43.5 33.9 1e-08 34.7 33.9 3.1 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) TFIIA PF03153.13 EGC29440.1 - 0.00073 19.7 16.2 0.00076 19.6 16.2 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGC29440.1 - 2 7.0 12.8 2.4 6.8 12.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CENP-N PF05238.13 EGC29440.1 - 3.1 7.0 14.4 3.8 6.7 14.4 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like Pex14_N PF04695.13 EGC29440.1 - 3.9 8.1 20.4 5.8 7.6 20.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM76 PF16046.5 EGC29440.1 - 4.5 6.6 14.7 5.2 6.3 14.7 1.1 1 0 0 1 1 1 0 FAM76 protein Ran_BP1 PF00638.18 EGC29441.1 - 8.3e-18 64.8 3.1 1.3e-17 64.2 2.5 1.8 1 1 0 1 1 1 1 RanBP1 domain CDC45 PF02724.14 EGC29441.1 - 0.14 10.4 21.5 0.19 10.0 4.5 2.2 2 0 0 2 2 2 0 CDC45-like protein BUD22 PF09073.10 EGC29441.1 - 4.4 6.5 40.2 0.99 8.7 13.7 2.2 2 0 0 2 2 2 0 BUD22 Dicty_CTDC PF00526.18 EGC29442.1 - 6.2e-40 134.7 96.7 2.4e-09 36.9 13.3 7.9 8 0 0 8 8 8 7 Dictyostelium (slime mold) repeat RNase_P_Rpp14 PF01900.19 EGC29443.1 - 2.1e-09 37.5 0.0 3e-09 37.0 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family SelK_SelG PF10961.8 EGC29443.1 - 0.45 11.2 3.1 0.96 10.1 0.8 2.1 2 0 0 2 2 2 0 Selenoprotein SelK_SelG PPR PF01535.20 EGC29444.1 - 2.7e-12 46.0 9.3 0.00027 21.0 0.1 6.3 7 0 0 7 7 7 3 PPR repeat PPR_2 PF13041.6 EGC29444.1 - 6.7e-12 45.4 18.9 3.3e-07 30.4 0.5 5.6 4 1 2 6 6 6 3 PPR repeat family PPR_1 PF12854.7 EGC29444.1 - 4.3e-08 32.7 6.6 2.6e-07 30.2 0.4 3.8 4 0 0 4 4 4 1 PPR repeat PPR_3 PF13812.6 EGC29444.1 - 4.5e-07 29.8 8.5 0.0091 16.1 0.1 5.4 4 1 1 5 5 5 2 Pentatricopeptide repeat domain ATP13 PF12921.7 EGC29444.1 - 9.5e-06 25.4 4.9 0.001 18.9 0.7 4.2 1 1 2 3 3 3 1 Mitochondrial ATPase expression ANAPC3 PF12895.7 EGC29444.1 - 0.0063 16.7 2.9 4.3 7.6 0.0 3.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 DED PF01335.21 EGC29444.1 - 0.0085 16.4 3.4 0.89 9.9 0.1 3.9 2 1 0 3 3 3 1 Death effector domain Cyclin_N PF00134.23 EGC29445.1 - 1.1e-27 96.3 0.1 6.6e-27 93.8 0.0 2.4 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC29445.1 - 8.9e-21 74.2 0.7 6.4e-20 71.4 0.4 2.6 2 0 0 2 2 2 1 Cyclin, C-terminal domain CBF_beta PF02312.17 EGC29446.1 - 0.021 14.5 0.0 0.029 14.0 0.0 1.2 1 0 0 1 1 1 0 Core binding factor beta subunit Alpha_Helical PF18489.1 EGC29447.1 - 0.036 14.2 0.7 5.7 7.1 0.1 3.6 3 0 0 3 3 3 0 Alpha helical domain Anoctamin PF04547.12 EGC29449.1 - 7.8e-21 74.4 18.8 7.8e-21 74.4 18.8 1.7 2 0 0 2 2 2 1 Calcium-activated chloride channel TMC PF07810.13 EGC29449.1 - 6.6e-08 33.1 0.1 6.6e-08 33.1 0.1 3.2 2 2 0 2 2 2 1 TMC domain RSN1_7TM PF02714.15 EGC29449.1 - 5e-05 22.8 16.5 5e-05 22.8 16.5 2.8 2 2 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate Claudin_2 PF13903.6 EGC29449.1 - 0.032 14.0 2.6 0.32 10.7 0.6 3.1 3 0 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction DUF2722 PF10846.8 EGC29449.1 - 0.45 9.4 11.0 0.63 8.9 11.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TMEM43 PF07787.12 EGC29449.1 - 0.93 8.8 5.4 0.73 9.2 0.5 2.4 2 0 0 2 2 2 0 Transmembrane protein 43 UPF0242 PF06785.11 EGC29449.1 - 1.4 9.0 0.0 1.4 9.0 0.0 3.5 3 1 1 4 4 4 0 Uncharacterised protein family (UPF0242) N-terminus FNIP PF05725.12 EGC29450.1 - 2.6e-18 65.9 72.1 5.1e-05 23.3 1.7 11.8 8 3 3 11 11 11 8 FNIP Repeat ApoL PF05461.11 EGC29450.1 - 0.026 13.8 1.8 0.041 13.2 1.8 1.2 1 0 0 1 1 1 0 Apolipoprotein L DUF726 PF05277.12 EGC29450.1 - 0.055 12.4 1.2 0.088 11.7 1.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) IncD PF17628.2 EGC29450.1 - 0.12 12.2 1.0 0.22 11.3 1.0 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D OTU PF02338.19 EGC29451.1 - 2.2e-14 54.1 0.0 2.2e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Pox_VLTF3 PF04947.14 EGC29451.1 - 0.0029 17.3 0.1 0.0029 17.3 0.1 2.3 2 0 0 2 2 2 1 Poxvirus Late Transcription Factor VLTF3 like SRI PF08236.11 EGC29451.1 - 0.03 14.5 2.8 0.11 12.7 0.2 2.5 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain TERB2 PF15101.6 EGC29451.1 - 0.16 12.0 13.9 0.099 12.7 7.8 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PAT1 PF09770.9 EGC29451.1 - 7.3 4.7 32.1 9.4 4.4 32.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PIN_12 PF16289.5 EGC29451.1 - 9.2 6.7 9.4 27 5.2 0.2 2.3 2 0 0 2 2 2 0 PIN domain CPW_WPC PF09717.10 EGC29454.1 - 0.13 13.3 19.3 6.5 7.8 1.0 5.3 1 1 2 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Phage_gp49_66 PF13876.6 EGC29454.1 - 1.8 9.0 6.2 1.4e+02 2.9 0.1 4.8 2 2 3 5 5 5 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family Dickkopf_N PF04706.12 EGC29454.1 - 5.5 7.6 13.0 55 4.3 0.9 4.0 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region IBR PF01485.21 EGC29458.1 - 5.1e-16 58.7 43.4 9.8e-09 35.3 15.1 2.5 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain PQ-loop PF04193.14 EGC29459.1 - 3.5e-22 77.9 12.6 8.6e-14 51.1 4.8 2.6 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.16 EGC29459.1 - 0.016 15.2 2.1 0.016 15.2 2.1 2.5 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SAP PF02037.27 EGC29460.1 - 0.0048 16.6 0.2 0.032 14.0 0.0 2.1 2 0 0 2 2 2 1 SAP domain DUF572 PF04502.13 EGC29460.1 - 1.9 8.0 29.5 2.3 7.8 29.5 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) bMG10 PF17973.1 EGC29461.1 - 1.8e-28 99.3 0.1 2.1e-27 95.8 0.1 2.6 2 0 0 2 2 2 1 Bacterial Alpha-2-macroglobulin MG10 domain MG2 PF01835.19 EGC29461.1 - 5.4e-09 36.4 0.0 4.2e-06 27.1 0.0 4.3 4 0 0 4 4 4 1 MG2 domain A2M PF00207.22 EGC29461.1 - 6.1e-07 29.2 0.0 3.6e-06 26.7 0.0 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family bMG3 PF11974.8 EGC29461.1 - 0.065 13.3 0.3 0.24 11.4 0.3 1.9 1 1 0 1 1 1 0 Bacterial alpha-2-macroglobulin MG3 domain CH PF00307.31 EGC29462.1 - 7.2e-18 64.8 0.2 7.1e-09 35.8 0.1 2.8 2 0 0 2 2 2 2 Calponin homology (CH) domain RA PF00788.23 EGC29462.1 - 2.3e-12 47.4 0.0 2.4e-05 24.9 0.0 3.4 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain PH PF00169.29 EGC29462.1 - 1.2e-06 28.9 1.0 6.9e-06 26.5 0.1 3.0 3 0 0 3 3 3 1 PH domain Ras_bdg_2 PF14847.6 EGC29462.1 - 0.00016 21.9 0.1 0.42 11.0 0.0 3.8 2 0 0 2 2 2 2 Ras-binding domain of Byr2 DNA_pack_N PF02500.15 EGC29462.1 - 6.4 6.5 7.3 19 4.9 7.3 1.8 1 0 0 1 1 1 0 Probable DNA packing protein, N-terminus dsrm PF00035.26 EGC29463.1 - 3.5e-12 46.8 2.3 6.5e-12 46.0 0.2 2.6 3 0 0 3 3 3 1 Double-stranded RNA binding motif Proteasom_PSMB PF10508.9 EGC29464.1 - 7e-20 71.0 9.7 2.9e-19 69.0 9.7 1.8 1 1 0 1 1 1 1 Proteasome non-ATPase 26S subunit Rcd1 PF04078.13 EGC29464.1 - 0.00073 18.9 1.6 0.64 9.3 0.7 2.7 2 1 0 2 2 2 2 Cell differentiation family, Rcd1-like LZ3wCH PF18517.1 EGC29464.1 - 0.031 14.4 1.2 20 5.4 0.1 3.6 3 0 0 3 3 3 0 Leucine zipper with capping helix domain Rsbr_N PF08678.10 EGC29464.1 - 0.1 12.7 6.1 12 5.9 0.1 3.7 3 1 0 3 3 3 0 Rsbr N terminal RICTOR_M PF14666.6 EGC29464.1 - 0.18 11.6 6.4 10 6.0 0.1 4.1 3 2 1 4 4 4 0 Rapamycin-insensitive companion of mTOR, middle domain Imm30 PF15565.6 EGC29464.1 - 0.2 11.8 7.1 1.6 8.8 0.5 4.1 3 1 0 3 3 3 0 Immunity protein 30 BCAS3 PF12490.8 EGC29465.1 - 1.4e-12 47.7 0.6 1.4e-12 47.7 0.6 3.2 2 1 0 2 2 2 1 Breast carcinoma amplified sequence 3 DUF2884 PF11101.8 EGC29465.1 - 0.07 12.6 0.2 0.14 11.6 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2884) Oxysterol_BP PF01237.18 EGC29466.1 - 4.4e-80 269.3 6.7 4.4e-78 262.7 6.7 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein JAB PF01398.21 EGC29467.1 - 3e-34 117.5 0.5 5e-34 116.8 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.6 EGC29467.1 - 4.7e-11 43.1 0.9 9.5e-11 42.1 0.9 1.5 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.6 EGC29467.1 - 4.9e-08 32.8 0.0 7.9e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain RRG8 PF17068.5 EGC29467.1 - 0.011 15.1 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Required for respiratory growth protein 8 mitochondrial UPF0172 PF03665.13 EGC29467.1 - 0.024 14.7 0.9 0.11 12.5 0.1 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Sec7 PF01369.20 EGC29468.1 - 1.3e-62 210.7 0.0 3.5e-62 209.3 0.0 1.8 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGC29468.1 - 2.5e-10 40.8 9.6 2.2e-07 31.3 0.4 3.4 3 1 0 3 3 3 2 PH domain PH_11 PF15413.6 EGC29468.1 - 0.048 14.1 0.1 0.048 14.1 0.1 4.0 4 0 0 4 4 4 0 Pleckstrin homology domain ApbA_C PF08546.11 EGC29469.1 - 0.1 12.8 0.0 0.14 12.4 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Sulfotransfer_1 PF00685.27 EGC29470.1 - 4.5e-17 62.4 2.0 4.5e-17 62.4 2.0 3.0 2 1 0 2 2 2 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGC29470.1 - 2.1e-12 47.9 0.6 4.4e-10 40.3 0.6 2.7 1 1 0 1 1 1 1 Sulfotransferase family Glycos_transf_1 PF00534.20 EGC29470.1 - 3.6e-12 46.2 1.5 7.3e-12 45.2 0.1 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC29470.1 - 1.9e-09 38.0 0.0 4.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC29470.1 - 1.4e-05 25.2 0.1 6.4e-05 23.0 0.0 2.2 2 1 0 2 2 2 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EGC29470.1 - 0.00032 20.5 0.9 0.0021 17.8 0.9 2.3 1 1 0 1 1 1 1 Starch synthase catalytic domain FNIP PF05725.12 EGC29471.1 - 3.4e-70 232.0 43.5 4.5e-15 55.5 5.3 7.8 5 2 0 7 7 7 7 FNIP Repeat tRNA-synt_2d PF01409.20 EGC29472.1 - 1.9e-49 168.4 4.5 3.3e-30 105.4 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.14 EGC29472.1 - 4.1e-23 81.6 2.7 4.2e-23 81.6 0.1 2.4 3 0 0 3 3 3 1 Ferredoxin-fold anticodon binding domain Pro_isomerase PF00160.21 EGC29473.1 - 4.4e-47 160.3 0.2 5e-47 160.1 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP PF05725.12 EGC29474.1 - 1.9e-14 53.5 22.4 0.00045 20.3 1.2 4.4 3 1 2 5 5 5 5 FNIP Repeat SAP PF02037.27 EGC29475.1 - 0.00043 20.0 0.1 0.0016 18.1 0.1 2.0 2 0 0 2 2 2 1 SAP domain HAD_2 PF13419.6 EGC29476.1 - 0.014 15.5 0.4 0.021 14.9 0.4 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase DUF3320 PF11784.8 EGC29476.1 - 0.021 14.8 0.0 0.041 13.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) DUF2722 PF10846.8 EGC29478.1 - 0.002 17.2 1.4 0.002 17.2 1.4 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) Chordopox_A13L PF05961.11 EGC29478.1 - 0.028 14.6 1.0 0.028 14.6 1.0 2.1 1 1 1 2 2 2 0 Chordopoxvirus A13L protein AJAP1_PANP_C PF15298.6 EGC29478.1 - 0.035 14.3 0.3 0.048 13.9 0.3 1.2 1 0 0 1 1 1 0 AJAP1/PANP C-terminus AAA_assoc_2 PF16193.5 EGC29478.1 - 0.14 12.5 1.1 0.36 11.2 1.1 1.7 1 0 0 1 1 1 0 AAA C-terminal domain DUF4834 PF16118.5 EGC29478.1 - 0.15 13.0 4.5 0.12 13.4 0.9 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) SelK_SelG PF10961.8 EGC29478.1 - 0.18 12.5 0.4 0.18 12.5 0.4 1.7 1 1 1 2 2 2 0 Selenoprotein SelK_SelG zf-C3HC4 PF00097.25 EGC29479.1 - 9.2e-09 35.0 7.4 2.1e-08 33.9 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29479.1 - 9.2e-08 31.8 9.7 1.7e-07 31.0 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC29479.1 - 1.3e-07 31.8 9.4 2.3e-07 31.0 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29479.1 - 1.4e-06 28.0 3.8 2.3e-06 27.4 3.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PWI PF01480.17 EGC29479.1 - 1.4e-06 28.5 0.5 1.4e-06 28.5 0.5 2.4 2 0 0 2 2 2 1 PWI domain zf-ANAPC11 PF12861.7 EGC29479.1 - 1.6e-05 24.8 2.1 3.2e-05 23.9 2.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGC29479.1 - 6.4e-05 23.2 8.4 0.0002 21.6 8.4 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC29479.1 - 0.0014 18.6 10.0 0.0032 17.5 10.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC29479.1 - 0.0018 18.2 6.9 0.0036 17.2 6.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Vps39_2 PF10367.9 EGC29479.1 - 0.083 13.3 0.0 0.083 13.3 0.0 4.0 4 1 1 5 5 4 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.6 EGC29479.1 - 0.11 12.6 10.8 0.28 11.4 10.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC29479.1 - 0.31 10.9 7.5 1.3 8.8 7.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Zn-C2H2_12 PF18112.1 EGC29479.1 - 0.87 10.1 5.7 0.81 10.2 0.4 2.7 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 EGC29479.1 - 2.6 8.0 13.3 1.5 8.7 6.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 MTBP_C PF14920.6 EGC29479.1 - 8.2 6.1 10.6 0.43 10.3 0.1 2.8 2 1 1 3 3 3 0 MDM2-binding SNARE PF05739.19 EGC29480.1 - 5.1e-05 23.2 4.2 0.00012 22.0 4.2 1.6 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EGC29480.1 - 0.002 17.9 2.2 0.0032 17.2 2.2 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 CK2S PF15011.6 EGC29480.1 - 0.71 9.8 5.2 6.3 6.7 0.2 2.7 3 0 0 3 3 3 0 Casein Kinase 2 substrate Mer2 PF09074.10 EGC29480.1 - 1.1 9.0 12.9 0.52 10.1 8.7 2.1 1 1 1 2 2 2 0 Mer2 Ac76 PF05814.11 EGC29480.1 - 1.6 8.8 6.4 2.1 8.4 0.1 2.8 3 0 0 3 3 3 0 Orf76 (Ac76) Phage_Gp23 PF10669.9 EGC29480.1 - 1.9 8.8 7.3 0.49 10.7 0.5 2.8 3 0 0 3 3 3 0 Protein gp23 (Bacteriophage A118) XhlA PF10779.9 EGC29480.1 - 2.6 8.3 12.1 0.14 12.4 4.0 2.7 2 0 0 2 2 2 0 Haemolysin XhlA 2OG-FeII_Oxy_2 PF13532.6 EGC29481.1 - 1.5e-13 51.3 0.0 3.2e-13 50.3 0.0 1.4 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Baculo_LEF5 PF04838.12 EGC29482.1 - 0.0049 16.9 0.3 0.0053 16.8 0.3 1.0 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 FNIP PF05725.12 EGC29486.1 - 3e-94 309.0 61.7 3e-11 43.3 0.9 12.7 4 3 6 13 13 13 13 FNIP Repeat LRR_5 PF13306.6 EGC29486.1 - 0.00018 21.5 8.0 0.11 12.5 0.2 4.1 4 1 1 5 5 5 3 BspA type Leucine rich repeat region (6 copies) Sel1 PF08238.12 EGC29487.1 - 1.8e-11 44.3 4.9 0.00095 19.8 0.1 4.6 5 0 0 5 5 5 3 Sel1 repeat TPR_2 PF07719.17 EGC29487.1 - 0.35 11.1 7.4 3.1 8.1 1.6 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC29487.1 - 0.7 10.3 8.9 17 5.9 0.8 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat EGF_Tenascin PF18720.1 EGC29488.1 - 2.9e-08 33.6 45.3 0.0016 18.5 6.8 4.8 4 0 0 4 4 4 3 Tenascin EGF domain EGF_2 PF07974.13 EGC29488.1 - 4.9e-07 30.0 60.1 0.0011 19.3 11.1 4.4 4 0 0 4 4 4 3 EGF-like domain TRP PF06011.12 EGC29488.1 - 0.01 14.6 29.6 0.07 11.9 20.6 3.3 1 1 1 3 3 3 0 Transient receptor potential (TRP) ion channel Dickkopf_N PF04706.12 EGC29489.1 - 0.016 15.6 15.8 0.016 15.6 15.8 6.1 4 2 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region Sgf11 PF08209.11 EGC29490.1 - 0.00012 21.5 0.2 0.00021 20.8 0.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DAGK_cat PF00781.24 EGC29491.1 - 1.2e-27 96.1 0.0 2.4e-27 95.1 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain Borrelia_orfD PF02999.14 EGC29491.1 - 0.0022 18.3 0.6 0.0062 16.8 0.6 1.7 1 0 0 1 1 1 1 Borrelia orf-D family SLIDE PF09111.10 EGC29491.1 - 8.8 6.4 10.5 4.7 7.3 2.8 2.8 2 1 0 2 2 2 0 SLIDE Lyase_aromatic PF00221.19 EGC29492.1 - 9.4e-142 472.9 0.0 1.1e-141 472.7 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Lipase_GDSL_3 PF14606.6 EGC29492.1 - 0.1 12.7 0.0 0.29 11.2 0.0 1.8 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family FNIP PF05725.12 EGC29493.1 - 2.8e-83 273.9 74.8 2.1e-13 50.2 1.0 13.5 9 3 6 15 15 15 14 FNIP Repeat HTH_ABP1_N PF18107.1 EGC29493.1 - 7.4 6.4 5.4 70 3.2 0.0 4.0 5 0 0 5 5 5 0 Fission yeast centromere protein N-terminal domain UDG PF03167.19 EGC29494.1 - 1.3e-15 57.7 0.0 1.6e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Acyl_transf_3 PF01757.22 EGC29495.1 - 1.2e-21 77.2 49.4 1.7e-20 73.4 51.1 1.9 2 0 0 2 2 2 1 Acyltransferase family CitMHS PF03600.16 EGC29495.1 - 1 8.5 11.5 0.091 11.9 6.4 1.8 2 0 0 2 2 2 0 Citrate transporter NAD_binding_2 PF03446.15 EGC29496.1 - 2.3e-53 180.6 0.6 3.1e-53 180.2 0.6 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.6 EGC29496.1 - 5.1e-32 110.7 0.0 1e-31 109.7 0.0 1.5 2 0 0 2 2 2 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.17 EGC29496.1 - 2.9e-09 37.4 0.0 8.5e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.19 EGC29496.1 - 1.9e-08 33.9 0.0 3.7e-08 32.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.12 EGC29496.1 - 8.5e-06 25.4 0.0 1.4e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain UDPG_MGDP_dh_N PF03721.14 EGC29496.1 - 7.7e-05 22.3 0.1 0.003 17.2 0.0 2.3 1 1 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGC29496.1 - 0.00033 20.6 0.1 0.00065 19.6 0.1 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGC29496.1 - 0.0074 16.5 0.0 0.015 15.6 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGC29496.1 - 0.011 15.8 0.0 0.019 15.1 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GFO_IDH_MocA PF01408.22 EGC29496.1 - 0.011 16.5 0.2 0.029 15.2 0.0 1.7 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold ApbA PF02558.16 EGC29496.1 - 0.011 15.3 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DpaA_N PF16924.5 EGC29496.1 - 0.016 15.3 0.0 0.054 13.6 0.0 2.0 1 1 1 2 2 2 0 Dipicolinate synthase subunit A N-terminal domain OCD_Mu_crystall PF02423.15 EGC29496.1 - 0.045 12.7 0.0 0.061 12.2 0.0 1.1 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family PDH PF02153.17 EGC29496.1 - 0.058 12.4 0.1 0.084 11.9 0.1 1.2 1 0 0 1 1 1 0 Prephenate dehydrogenase DUF3475 PF11961.8 EGC29496.1 - 0.13 12.3 0.1 0.29 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3475) Sec7 PF01369.20 EGC29497.1 - 1.1e-66 224.1 1.9 1.1e-66 224.1 1.9 2.2 2 0 0 2 2 2 1 Sec7 domain PH PF00169.29 EGC29497.1 - 1.3e-18 67.4 0.8 1.3e-18 67.4 0.8 2.9 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EGC29497.1 - 1.4e-06 28.6 0.6 1.4e-06 28.6 0.6 3.5 3 1 0 3 3 3 1 Pleckstrin homology domain PH_9 PF15410.6 EGC29497.1 - 0.052 13.9 0.4 4.9 7.6 0.4 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain WD40 PF00400.32 EGC29498.1 - 2.6e-09 37.5 12.1 0.00031 21.5 0.0 6.8 8 0 0 8 8 8 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC29498.1 - 1.3e-06 28.6 0.2 0.0046 17.2 0.0 4.3 2 2 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC29498.1 - 4.5e-05 23.4 9.7 0.00081 19.3 0.0 3.6 3 1 0 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mucin PF01456.17 EGC29498.1 - 0.7 9.9 28.3 1.2 9.1 28.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein IBR PF01485.21 EGC29499.1 - 5.7e-23 80.9 46.4 1e-14 54.5 4.8 4.5 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGC29499.1 - 0.00032 20.7 8.4 0.00032 20.7 8.4 3.9 3 2 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC29499.1 - 0.0016 18.2 10.9 0.0016 18.2 10.9 5.2 3 3 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC29499.1 - 0.0023 18.2 11.2 0.0023 18.2 11.2 3.9 3 2 0 3 3 3 2 Ring finger domain zf-C3HC4_2 PF13923.6 EGC29499.1 - 0.0057 16.5 8.1 0.0057 16.5 8.1 5.0 4 1 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29499.1 - 0.029 14.4 45.0 0.034 14.1 9.4 4.2 2 1 2 4 4 4 0 zinc-RING finger domain GFD1 PF17331.2 EGC29499.1 - 0.038 14.2 1.5 0.038 14.2 1.5 1.9 2 0 0 2 2 2 0 GFD1 mRNA transport factor C1_4 PF07975.12 EGC29499.1 - 0.044 14.0 1.5 0.044 14.0 1.5 4.8 3 3 1 4 4 4 0 TFIIH C1-like domain zf-rbx1 PF12678.7 EGC29499.1 - 5.2 7.4 30.5 1.5 9.2 6.4 3.7 3 1 0 3 3 3 0 RING-H2 zinc finger domain MIT PF04212.18 EGC29500.1 - 2.8e-32 110.6 10.8 4.5e-18 65.1 1.7 2.8 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain FliS PF02561.14 EGC29500.1 - 0.016 15.5 0.6 3.5 7.9 0.0 2.5 2 0 0 2 2 2 0 Flagellar protein FliS TPR_1 PF00515.28 EGC29500.1 - 0.034 14.0 0.6 12 5.9 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Aida_N PF08910.10 EGC29500.1 - 0.056 13.9 0.1 0.49 10.8 0.1 2.3 2 0 0 2 2 2 0 Aida N-terminus SHNi-TPR PF10516.9 EGC29500.1 - 0.11 12.0 0.2 0.51 9.8 0.0 2.2 2 0 0 2 2 2 0 SHNi-TPR WD40 PF00400.32 EGC29501.1 - 1.4e-34 117.5 23.2 1.1e-05 26.1 0.2 10.9 11 0 0 11 11 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC29501.1 - 3.9e-15 55.9 5.4 0.0045 17.3 0.1 7.3 3 3 5 9 9 9 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC29501.1 - 2.7e-06 27.0 1.4 0.014 14.8 0.0 3.5 3 1 0 3 3 3 2 WD40-like domain PQQ_2 PF13360.6 EGC29501.1 - 0.00015 21.5 1.5 0.26 10.8 0.4 3.5 2 1 0 3 3 3 2 PQQ-like domain PD40 PF07676.12 EGC29501.1 - 0.0039 17.1 0.6 11 6.0 0.0 4.7 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WDCP PF15390.6 EGC29501.1 - 0.0071 14.8 0.8 0.11 10.9 0.1 2.1 2 0 0 2 2 2 1 WD repeat and coiled-coil-containing protein family Nup160 PF11715.8 EGC29501.1 - 0.014 14.1 1.0 0.13 10.9 0.1 2.5 3 0 0 3 3 3 0 Nucleoporin Nup120/160 SdiA-regulated PF06977.11 EGC29501.1 - 0.022 14.0 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 SdiA-regulated IKI3 PF04762.12 EGC29501.1 - 0.033 12.2 1.7 0.38 8.7 0.1 2.6 3 1 1 4 4 4 0 IKI3 family HCO3_cotransp PF00955.21 EGC29502.1 - 0.54 9.0 6.4 0.6 8.9 6.4 1.0 1 0 0 1 1 1 0 HCO3- transporter family Secretin_N_2 PF07655.13 EGC29502.1 - 5.9 7.5 24.5 9.2 6.9 24.5 1.5 1 1 0 1 1 1 0 Secretin N-terminal domain NTP_transf_2 PF01909.23 EGC29504.1 - 0.015 15.5 0.6 0.19 12.0 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain SSP160 PF06933.11 EGC29504.1 - 0.22 9.7 8.1 0.27 9.4 8.1 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGC29504.1 - 1 9.3 10.0 1.7 8.6 10.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) B277 PF17623.2 EGC29504.1 - 2 7.4 4.0 3.9 6.5 4.0 1.5 1 0 0 1 1 1 0 Domain of unknown function E1-E2_ATPase PF00122.20 EGC29505.1 - 2.5e-47 160.7 1.0 2.5e-47 160.7 1.0 2.2 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGC29505.1 - 7.4e-43 146.4 3.4 7.4e-43 146.4 3.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGC29505.1 - 3.1e-24 84.9 0.0 6.2e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_N PF00690.26 EGC29505.1 - 1.7e-21 75.7 0.0 3.2e-21 74.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase PF00702.26 EGC29505.1 - 5.4e-20 72.6 0.1 2.6e-17 63.8 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC29505.1 - 1.5e-06 28.1 1.1 0.00044 20.1 0.4 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC29505.1 - 0.097 13.1 0.0 0.94 9.9 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase zf-CCHC_3 PF13917.6 EGC29506.1 - 2.7e-07 30.4 0.1 8.6e-07 28.8 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGC29506.1 - 0.54 10.4 2.5 1 9.6 2.5 1.5 1 0 0 1 1 1 0 Zinc knuckle EF-hand_6 PF13405.6 EGC29508.1 - 7.1e-13 47.4 8.7 0.0042 16.9 0.1 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC29508.1 - 8e-12 43.8 11.8 0.0066 15.9 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_7 PF13499.6 EGC29508.1 - 3.8e-11 43.3 10.2 6.9e-06 26.4 3.0 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC29508.1 - 2.4e-06 27.3 5.8 0.052 13.4 0.1 3.6 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC29508.1 - 6.8e-05 23.2 4.5 0.055 13.8 0.3 3.0 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGC29508.1 - 0.001 19.0 0.8 0.16 11.9 0.0 2.7 2 1 1 3 3 3 1 Caleosin related protein PP2C_C PF07830.13 EGC29508.1 - 0.0059 17.0 0.7 0.56 10.7 0.1 2.2 2 0 0 2 2 2 1 Protein serine/threonine phosphatase 2C, C-terminal domain DUF4777 PF16007.5 EGC29508.1 - 0.0092 16.2 0.1 2.4 8.5 0.0 3.6 2 2 2 4 4 4 1 Domain of unknown function (DUF4777) EF-hand_5 PF13202.6 EGC29508.1 - 0.021 14.3 6.2 1.9 8.2 0.0 4.1 4 0 0 4 4 4 0 EF hand T3SS_ATPase_C PF18269.1 EGC29508.1 - 0.1 12.5 0.1 0.9 9.4 0.1 2.2 2 0 0 2 2 2 0 T3SS EscN ATPase C-terminal domain EF-hand_10 PF14788.6 EGC29508.1 - 0.16 11.9 1.9 3.1 7.7 0.3 2.9 2 1 0 2 2 2 0 EF hand HP0268 PF18618.1 EGC29508.1 - 0.85 10.1 7.7 4.9 7.7 0.7 2.7 2 1 1 3 3 3 0 HP0268 Formyl_trans_N PF00551.19 EGC29509.1 - 2.4e-22 79.5 0.0 3.8e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.18 EGC29509.1 - 0.013 15.8 0.2 0.16 12.2 0.2 2.6 2 1 0 2 2 2 0 Formyl transferase, C-terminal domain Luteo_coat PF00894.18 EGC29509.1 - 0.087 12.7 0.0 8.5 6.3 0.0 2.4 2 0 0 2 2 2 0 Luteovirus coat protein PH PF00169.29 EGC29510.1 - 5.1e-08 33.4 5.5 0.0037 17.8 0.2 3.3 3 0 0 3 3 3 2 PH domain PH_4 PF15404.6 EGC29510.1 - 0.0008 19.3 0.6 0.0008 19.3 0.6 3.8 2 2 2 4 4 4 2 Pleckstrin homology domain Methyltransf_23 PF13489.6 EGC29511.1 - 2.5e-18 66.5 0.0 3.2e-18 66.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC29511.1 - 3.3e-17 62.9 0.0 5.6e-17 62.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC29511.1 - 1.2e-15 57.6 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29511.1 - 1e-13 51.8 0.0 1.8e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29511.1 - 8.3e-11 42.5 0.1 8.3e-11 42.5 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGC29511.1 - 3.3e-08 33.3 0.1 5.1e-08 32.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGC29511.1 - 1.4e-07 31.1 0.0 1.9e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.11 EGC29511.1 - 4.5e-07 29.1 0.0 6.1e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EGC29511.1 - 2.7e-06 26.9 0.0 3.8e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC29511.1 - 0.00072 19.1 0.3 0.0023 17.5 0.3 1.8 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.11 EGC29511.1 - 0.00086 19.0 0.0 0.0012 18.5 0.0 1.2 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_32 PF13679.6 EGC29511.1 - 0.0015 18.5 0.1 0.0034 17.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain GidB PF02527.15 EGC29511.1 - 0.0017 17.7 0.0 1.4 8.2 0.0 2.2 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G Pox_MCEL PF03291.16 EGC29511.1 - 0.018 14.2 0.1 0.038 13.1 0.1 1.5 1 1 0 1 1 1 0 mRNA capping enzyme DREV PF05219.12 EGC29511.1 - 0.022 13.9 0.1 0.03 13.4 0.1 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_4 PF02390.17 EGC29511.1 - 0.031 13.7 0.1 2.9 7.3 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase MetW PF07021.12 EGC29511.1 - 0.1 12.1 0.6 0.48 10.0 0.6 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW Cons_hypoth95 PF03602.15 EGC29511.1 - 0.11 12.1 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_11 PF08241.12 EGC29512.1 - 6.1e-15 55.7 0.0 1.8e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29512.1 - 3.1e-11 43.8 0.0 1e-10 42.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC29512.1 - 4e-09 36.4 2.1 1.3e-08 34.8 2.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC29512.1 - 5.2e-07 29.6 0.0 5.2e-07 29.6 0.0 2.8 1 1 2 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29512.1 - 4.2e-05 24.2 0.1 4.2e-05 24.2 0.1 4.0 3 2 0 3 3 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC29512.1 - 0.0074 15.7 0.0 0.013 14.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Eapp_C PF10238.9 EGC29512.1 - 0.36 10.9 14.9 0.91 9.6 4.2 2.4 2 0 0 2 2 2 0 E2F-associated phosphoprotein DDHD PF02862.17 EGC29512.1 - 0.43 10.7 15.9 0.23 11.6 1.2 2.1 2 0 0 2 2 2 0 DDHD domain Vfa1 PF08432.10 EGC29512.1 - 0.45 10.8 24.9 0.34 11.2 5.3 2.2 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF5308 PF17233.2 EGC29512.1 - 0.72 10.1 7.2 3.6 7.8 0.3 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF3750 PF12570.8 EGC29512.1 - 1 10.0 4.8 0.46 11.2 2.2 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF3750) RP-C_C PF11800.8 EGC29512.1 - 1.1 9.3 14.3 3 7.9 1.0 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Tim54 PF11711.8 EGC29512.1 - 1.5 7.5 20.8 2.1 7.1 4.4 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Pex14_N PF04695.13 EGC29512.1 - 1.6 9.4 16.3 0.41 11.3 1.4 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Apc15p PF05841.11 EGC29512.1 - 2.4 9.0 22.3 0.097 13.5 3.2 2.3 2 0 0 2 2 2 0 Apc15p protein Spore_coat_CotO PF14153.6 EGC29512.1 - 3.2 7.6 24.3 0.11 12.5 3.5 2.1 2 0 0 2 2 2 0 Spore coat protein CotO SpoIIP PF07454.11 EGC29512.1 - 3.3 7.1 22.4 0.32 10.4 3.6 2.3 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) SR-25 PF10500.9 EGC29512.1 - 3.4 7.2 21.2 0.47 10.0 11.7 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Neur_chan_memb PF02932.16 EGC29512.1 - 4.8 7.2 13.6 3.9 7.5 0.3 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region MMR1 PF08505.10 EGC29512.1 - 5.2 7.3 24.7 4.4 7.5 4.5 2.1 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein SUIM_assoc PF16619.5 EGC29512.1 - 5.4 7.2 22.6 0.066 13.3 5.7 2.5 3 0 0 3 3 2 0 Unstructured region C-term to UIM in Ataxin3 DUF1840 PF08895.11 EGC29512.1 - 5.7 7.3 14.0 0.46 10.8 1.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) SKA1 PF07160.12 EGC29512.1 - 9.2 6.0 22.5 0.74 9.6 2.6 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SAP PF02037.27 EGC29513.1 - 3e-12 46.0 0.0 7.8e-07 28.7 0.1 2.8 2 0 0 2 2 2 2 SAP domain Cwf_Cwc_15 PF04889.12 EGC29513.1 - 3.9 7.1 40.4 1.3 8.7 23.1 2.2 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein NAD_binding_1 PF00175.21 EGC29514.1 - 1e-14 55.1 0.0 3e-14 53.6 0.0 1.8 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGC29514.1 - 2.3e-12 47.1 0.0 5.7e-12 45.9 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGC29514.1 - 2.9e-10 40.5 0.2 1.6e-08 34.8 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Globin PF00042.22 EGC29514.1 - 3.3e-10 40.5 0.8 1.1e-09 38.9 0.0 2.2 2 0 0 2 2 2 1 Globin Protoglobin PF11563.8 EGC29514.1 - 0.077 12.9 0.1 0.16 11.9 0.1 1.5 1 1 0 1 1 1 0 Protoglobin Nup88 PF10168.9 EGC29516.1 - 4.1e-12 44.8 0.8 4.8e-12 44.5 0.8 1.0 1 0 0 1 1 1 1 Nuclear pore component Ima1_N PF09779.9 EGC29518.1 - 4.4e-20 72.9 31.8 4.3e-19 69.7 12.9 3.1 2 1 1 3 3 3 2 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.11 EGC29518.1 - 0.1 12.5 2.3 0.78 9.7 0.2 2.6 2 0 0 2 2 2 0 Putative transposase DNA-binding domain DUF608 PF04685.13 EGC29519.1 - 8.5e-147 489.0 6.0 1.3e-146 488.4 6.0 1.3 1 0 0 1 1 1 1 Glycosyl-hydrolase family 116, catalytic region Glyco_hydr_116N PF12215.8 EGC29519.1 - 2.1e-109 365.8 2.4 2.1e-109 365.8 2.4 2.3 2 1 0 2 2 2 1 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term GDE_C PF06202.14 EGC29519.1 - 0.002 17.1 0.3 0.011 14.7 0.3 2.1 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase JmjC PF02373.22 EGC29520.1 - 1.7e-11 44.6 0.0 1.7e-11 44.6 0.0 5.5 2 1 4 6 6 6 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGC29520.1 - 6.4e-09 35.9 22.4 6.4e-09 35.9 22.4 3.1 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 BRCT_2 PF16589.5 EGC29521.1 - 6.3e-16 58.6 4.0 5e-08 33.3 0.0 3.6 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC29521.1 - 3e-12 46.8 0.6 2.2e-06 27.9 0.2 2.8 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain RAMA PF18755.1 EGC29521.1 - 1.7e-05 25.2 0.0 8.8e-05 22.9 0.0 2.3 1 0 0 1 1 1 1 Restriction Enzyme Adenine Methylase Associated PTCB-BRCT PF12738.7 EGC29521.1 - 0.0002 21.2 0.1 0.00073 19.4 0.1 1.9 2 0 0 2 2 2 1 twin BRCT domain BRCT_3 PF18428.1 EGC29521.1 - 0.0084 16.2 0.1 0.2 11.7 0.1 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RRM_1 PF00076.22 EGC29522.1 - 0.00011 22.0 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ocnus PF05005.15 EGC29522.1 - 0.15 12.2 2.3 0.59 10.3 0.6 2.2 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) Synaptobrevin PF00957.21 EGC29523.1 - 2.4e-12 46.5 0.5 3.5e-12 46.0 0.5 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGC29523.1 - 0.019 15.0 0.0 0.032 14.3 0.0 1.4 1 0 0 1 1 1 0 Regulated-SNARE-like domain NmrA PF05368.13 EGC29524.1 - 2e-22 79.9 0.2 2.5e-22 79.6 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC29524.1 - 5.5e-17 62.2 0.0 7.8e-17 61.8 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Sacchrp_dh_NADP PF03435.18 EGC29524.1 - 1.3e-07 32.0 0.1 4.1e-07 30.3 0.1 2.0 1 1 1 2 2 2 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EGC29524.1 - 1.5e-05 24.1 0.1 3.2e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC29524.1 - 0.00063 19.3 0.2 0.0077 15.7 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGC29524.1 - 0.001 18.3 0.3 0.0026 16.9 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.10 EGC29524.1 - 0.0023 17.9 0.0 0.016 15.1 0.0 2.1 2 1 1 3 3 3 1 KR domain TrkA_N PF02254.18 EGC29524.1 - 0.0076 16.5 0.1 0.032 14.5 0.1 2.2 1 1 1 2 2 2 1 TrkA-N domain GFO_IDH_MocA PF01408.22 EGC29524.1 - 0.035 14.9 0.0 0.068 14.0 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F420_oxidored PF03807.17 EGC29524.1 - 0.037 14.6 0.2 0.12 12.9 0.2 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.24 EGC29524.1 - 0.12 12.8 0.1 0.53 10.7 0.1 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Homeobox_KN PF05920.11 EGC29525.1 - 2.4e-13 49.7 1.4 2.4e-13 49.7 1.4 1.7 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EGC29525.1 - 9.2e-06 25.4 0.1 1.9e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 Homeodomain LIM PF00412.22 EGC29527.1 - 3.6e-10 39.9 10.2 5e-10 39.5 10.2 1.2 1 0 0 1 1 1 1 LIM domain C1_1 PF00130.22 EGC29527.1 - 0.14 12.1 11.0 0.64 9.9 5.3 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_9 PF13187.6 EGC29527.1 - 0.4 10.9 9.4 0.073 13.2 5.0 2.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain FNIP PF05725.12 EGC29530.1 - 3.6e-100 327.9 50.7 1.8e-12 47.2 0.8 13.9 6 4 4 13 13 13 13 FNIP Repeat LRR_5 PF13306.6 EGC29530.1 - 5.4e-06 26.4 6.4 3.8e-05 23.7 0.0 4.2 2 1 2 5 5 5 1 BspA type Leucine rich repeat region (6 copies) DUF249 PF03158.13 EGC29530.1 - 0.097 12.4 0.1 4.4 7.0 0.0 3.0 3 0 0 3 3 3 0 Multigene family 530 protein ABC_tran_CTD PF16326.5 EGC29531.1 - 0.06 13.6 0.4 0.15 12.4 0.4 1.6 1 0 0 1 1 1 0 ABC transporter C-terminal domain zf-AN1 PF01428.16 EGC29532.1 - 5.4e-20 71.3 35.8 4.1e-11 42.9 10.4 2.8 3 0 0 3 3 3 2 AN1-like Zinc finger S-AdoMet_synt_C PF02773.16 EGC29533.1 - 4.6e-68 227.5 0.1 1.1e-67 226.3 0.0 1.7 2 0 0 2 2 2 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.16 EGC29533.1 - 2.1e-46 157.0 0.0 4.2e-46 156.1 0.0 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.20 EGC29533.1 - 3.8e-44 149.4 0.3 7.8e-44 148.4 0.3 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain TPR_8 PF13181.6 EGC29534.1 - 0.0045 17.1 0.5 0.025 14.7 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC29534.1 - 0.007 16.6 0.5 0.026 14.8 0.0 2.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC29534.1 - 0.018 14.9 0.2 0.061 13.2 0.2 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat 3-PAP PF12578.8 EGC29534.1 - 0.13 12.0 2.8 0.14 11.9 0.6 2.2 2 0 0 2 2 2 0 Myotubularin-associated protein Lebercilin PF15619.6 EGC29534.1 - 2.9 7.5 25.1 0.61 9.7 9.5 3.6 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease RSS_P20 PF11757.8 EGC29534.1 - 3.8 8.0 13.8 0.36 11.3 4.4 3.0 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Pkinase PF00069.25 EGC29535.1 - 7e-49 166.5 0.4 3.2e-48 164.4 0.4 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29535.1 - 1.1e-32 113.3 0.2 4e-23 82.0 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC29535.1 - 0.037 13.3 0.6 0.097 12.0 0.0 1.9 3 0 0 3 3 3 0 Kinase-like SH3_9 PF14604.6 EGC29536.1 - 2.4e-26 91.3 2.9 2.2e-12 46.6 1.2 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGC29536.1 - 3.5e-25 87.4 4.4 1.2e-14 53.7 0.2 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGC29536.1 - 3.4e-23 81.1 0.4 1.3e-11 44.0 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain HR1 PF02185.16 EGC29536.1 - 0.0001 22.4 23.2 0.037 14.1 4.8 3.6 3 0 0 3 3 3 3 Hr1 repeat BLOC1_2 PF10046.9 EGC29536.1 - 0.0085 16.4 17.6 5.1 7.5 4.6 4.4 3 1 1 4 4 4 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF3375 PF11855.8 EGC29536.1 - 0.027 13.4 5.1 1.5 7.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3375) APG6_N PF17675.1 EGC29536.1 - 0.18 12.3 25.7 1.9 9.0 0.6 3.6 2 1 1 3 3 3 0 Apg6 coiled-coil region DivIC PF04977.15 EGC29536.1 - 0.19 11.5 25.7 0.23 11.3 1.1 4.6 4 1 0 4 4 4 0 Septum formation initiator Baculo_PEP_C PF04513.12 EGC29536.1 - 0.19 11.8 8.5 0.76 9.8 0.5 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus TFR_dimer PF04253.15 EGC29536.1 - 0.4 10.8 2.2 4.9 7.3 0.1 2.9 3 1 0 3 3 2 0 Transferrin receptor-like dimerisation domain V_ATPase_I PF01496.19 EGC29536.1 - 0.84 7.5 15.3 0.57 8.0 10.3 2.2 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Fez1 PF06818.15 EGC29536.1 - 0.93 9.9 23.9 4.8 7.6 4.4 2.8 2 1 1 3 3 3 0 Fez1 Exonuc_VII_L PF02601.15 EGC29536.1 - 1 8.9 11.8 1.8 8.1 7.4 2.2 2 0 0 2 2 2 0 Exonuclease VII, large subunit CorA PF01544.18 EGC29536.1 - 1.2 8.3 10.2 2.1 7.6 1.5 3.1 3 0 0 3 3 3 0 CorA-like Mg2+ transporter protein PRKG1_interact PF15898.5 EGC29536.1 - 1.4 9.8 25.2 0.44 11.5 0.2 3.6 2 1 1 3 3 3 0 cGMP-dependent protein kinase interacting domain ABC_tran_CTD PF16326.5 EGC29536.1 - 2.8 8.3 17.4 0.14 12.4 1.3 3.8 2 1 2 4 4 4 0 ABC transporter C-terminal domain FapA PF03961.13 EGC29536.1 - 3 6.4 29.1 0.25 9.9 8.3 3.1 2 1 1 3 3 3 0 Flagellar Assembly Protein A DUF4140 PF13600.6 EGC29536.1 - 3.5 8.1 14.5 5.4 7.5 0.3 4.3 3 1 1 4 4 4 0 N-terminal domain of unknown function (DUF4140) DUF1192 PF06698.11 EGC29536.1 - 4 7.6 6.7 16 5.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) DUF5446 PF17522.2 EGC29536.1 - 7.4 6.8 12.2 0.83 9.9 0.1 3.7 3 1 0 3 3 3 0 Family of unknown function (DUF5446) MMR_HSR1 PF01926.23 EGC29537.1 - 2.1e-07 31.0 1.5 2.8e-06 27.4 0.4 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase VWA_2 PF13519.6 EGC29537.1 - 5.8e-05 23.7 0.4 0.0023 18.5 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain Dynamin_N PF00350.23 EGC29537.1 - 0.007 16.4 6.9 0.5 10.4 0.3 3.6 3 1 1 4 4 4 2 Dynamin family AAA_16 PF13191.6 EGC29537.1 - 0.044 14.2 0.0 0.079 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain LPMO_10 PF03067.15 EGC29539.1 - 2.2e-05 25.2 0.1 3.1e-05 24.7 0.1 1.3 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading IMS PF00817.20 EGC29540.1 - 0.016 15.2 0.1 0.14 12.1 0.0 2.2 2 0 0 2 2 2 0 impB/mucB/samB family HEAT_2 PF13646.6 EGC29543.1 - 1.4e-36 124.7 8.8 1.9e-16 60.2 0.2 3.1 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.16 EGC29543.1 - 3.1e-27 92.4 0.2 6.6e-05 23.2 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.22 EGC29543.1 - 8.6e-17 59.8 4.7 0.024 14.9 0.0 6.3 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.6 EGC29543.1 - 2.8e-07 30.9 4.4 3.9 8.1 0.1 5.5 3 1 2 5 5 5 4 HEAT-like repeat Cnd1 PF12717.7 EGC29543.1 - 1.4e-05 25.2 1.6 1.6 8.7 0.1 4.5 2 2 2 4 4 4 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.23 EGC29543.1 - 0.0015 18.5 1.9 0.62 10.2 0.0 3.7 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vitellogenin_N PF01347.22 EGC29543.1 - 0.0049 15.3 0.1 0.33 9.3 0.0 2.1 2 0 0 2 2 2 2 Lipoprotein amino terminal region DUF3385 PF11865.8 EGC29543.1 - 0.018 14.9 0.0 0.15 11.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TAF6_C PF07571.13 EGC29543.1 - 0.019 15.3 0.1 4.2 7.8 0.0 3.8 2 2 1 3 3 3 0 TAF6 C-terminal HEAT repeat domain C2 PF00168.30 EGC29544.1 - 3.7e-09 36.8 0.0 5.8e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 C2 domain Peptidase_C25_C PF03785.14 EGC29544.1 - 0.043 13.6 0.0 0.073 12.9 0.0 1.3 1 0 0 1 1 1 0 Peptidase family C25, C terminal ig-like domain SNF2_N PF00176.23 EGC29545.1 - 3.4e-45 154.3 0.1 3.4e-45 154.3 0.1 2.3 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC29545.1 - 1.5e-14 54.3 0.6 6.6e-14 52.2 0.6 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.11 EGC29545.1 - 0.16 12.0 11.6 0.33 10.9 11.6 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ependymin PF00811.18 EGC29546.1 - 3.7e-05 24.0 0.7 3.7e-05 24.0 0.7 2.1 2 0 0 2 2 2 1 Ependymin zf-RING_2 PF13639.6 EGC29547.1 - 4.7e-08 33.2 10.0 8.2e-08 32.5 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29547.1 - 4.9e-08 32.7 8.0 8.5e-08 31.9 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29547.1 - 5.8e-08 32.5 9.6 1.8e-07 30.9 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29547.1 - 4.7e-07 29.5 8.3 8.2e-07 28.8 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29547.1 - 3.3e-06 27.3 7.3 9.1e-06 25.9 7.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC29547.1 - 0.0016 18.4 4.9 0.0036 17.3 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC29547.1 - 0.0074 16.2 9.7 0.015 15.2 9.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC29547.1 - 0.019 15.1 9.2 0.066 13.4 9.1 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC29547.1 - 0.085 12.7 9.3 0.31 10.9 9.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 WBP-1 PF11669.8 EGC29547.1 - 0.15 12.7 0.1 0.15 12.7 0.1 4.9 3 1 2 5 5 5 0 WW domain-binding protein 1 zf-RING_4 PF14570.6 EGC29547.1 - 0.74 9.7 10.9 7.6 6.4 10.7 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC29547.1 - 0.98 9.5 5.7 2.7 8.1 5.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3021 PF11457.8 EGC29547.1 - 1 9.7 4.8 1.7 9.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Zn_ribbon_17 PF17120.5 EGC29547.1 - 1.1 8.9 7.9 1.9 8.2 7.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DZR PF12773.7 EGC29547.1 - 3 7.9 11.7 0.45 10.6 7.2 2.0 2 0 0 2 2 1 0 Double zinc ribbon FAD_binding_4 PF01565.23 EGC29549.1 - 1.1e-25 90.0 0.1 2.2e-25 89.0 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC29549.1 - 2.5e-06 27.5 0.1 8.4e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 Berberine and berberine like FlgT_M PF16539.5 EGC29549.1 - 0.33 11.1 6.4 0.22 11.6 4.5 1.6 2 0 0 2 2 2 0 Flagellar assembly protein T, middle domain SelP_N PF04592.14 EGC29549.1 - 2.8 7.3 22.9 4.9 6.5 22.9 1.4 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ank_2 PF12796.7 EGC29550.1 - 1e-25 90.1 0.0 1.2e-12 48.3 0.0 2.0 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC29550.1 - 1.3e-20 73.5 0.0 2.9e-08 34.1 0.0 3.9 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC29550.1 - 9.5e-19 65.5 0.0 7e-05 22.9 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.30 EGC29550.1 - 6.3e-17 61.2 0.0 5.1e-05 23.5 0.0 3.9 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGC29550.1 - 1.2e-14 54.2 0.0 6.2e-05 23.2 0.0 3.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) RTA1 PF04479.13 EGC29551.1 - 2.3e-52 177.6 4.5 3.4e-52 177.1 4.5 1.2 1 0 0 1 1 1 1 RTA1 like protein BT1 PF03092.16 EGC29551.1 - 0.0069 14.7 1.0 0.0092 14.2 1.0 1.3 1 0 0 1 1 1 1 BT1 family HisKA_7TM PF16927.5 EGC29551.1 - 0.0079 16.3 6.1 0.0079 16.3 6.1 2.1 1 1 1 2 2 2 1 N-terminal 7TM region of histidine kinase PrcB_C PF14343.6 EGC29551.1 - 0.011 15.9 0.0 0.032 14.4 0.0 1.8 1 0 0 1 1 1 0 PrcB C-terminal DUF2070 PF09843.9 EGC29551.1 - 0.021 13.2 8.7 0.028 12.7 8.7 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5325 PF17259.2 EGC29551.1 - 5.8 6.9 8.1 1 9.3 0.1 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5325) MSC PF09402.10 EGC29553.1 - 3.2e-21 76.2 0.6 3.2e-21 76.2 0.6 3.5 2 2 1 3 3 3 1 Man1-Src1p-C-terminal domain TMEM154 PF15102.6 EGC29554.1 - 0.00064 19.6 8.3 0.012 15.5 0.4 2.4 2 0 0 2 2 2 2 TMEM154 protein family Orf78 PF06024.12 EGC29554.1 - 0.003 17.8 0.1 0.003 17.8 0.1 1.7 2 0 0 2 2 2 1 Orf78 (ac78) DUF2207 PF09972.9 EGC29554.1 - 0.012 14.4 0.3 0.021 13.6 0.0 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Dicty_REP PF05086.12 EGC29554.1 - 0.77 7.7 7.6 0.14 10.1 3.7 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EGC29554.1 - 3.4 5.7 8.8 4.6 5.3 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF515 PF04415.12 EGC29554.1 - 9.8 4.4 9.1 2.4 6.4 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF515) Laminin_EGF PF00053.24 EGC29555.1 - 0.011 15.9 23.1 0.21 11.8 10.2 2.7 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 EGC29555.1 - 0.016 15.6 17.2 0.016 15.6 17.2 3.2 4 0 0 4 4 4 0 EGF-like domain EGF_Tenascin PF18720.1 EGC29555.1 - 0.65 10.1 22.4 0.026 14.6 8.5 2.6 2 0 0 2 2 2 0 Tenascin EGF domain DUF3793 PF12672.7 EGC29556.1 - 0.029 14.4 0.0 0.05 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) Peptidase_S49_N PF08496.10 EGC29557.1 - 0.57 10.2 2.4 0.67 10.0 2.4 1.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal PH PF00169.29 EGC29558.1 - 1.8e-06 28.4 9.2 2.4e-05 24.8 4.8 3.1 2 1 0 2 2 2 1 PH domain PH_3 PF14593.6 EGC29558.1 - 0.051 13.7 4.5 0.047 13.8 1.1 2.6 2 0 0 2 2 2 0 PH domain TAS2R PF05296.13 EGC29558.1 - 7 5.7 9.6 0.11 11.6 1.3 2.0 2 0 0 2 2 2 0 Taste receptor protein (TAS2R) Mito_carr PF00153.27 EGC29559.1 - 2e-66 220.0 5.1 2e-24 85.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HypA PF01155.19 EGC29560.1 - 0.032 14.3 10.7 0.61 10.1 0.3 3.5 1 1 2 3 3 3 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Stc1 PF12898.7 EGC29560.1 - 0.14 12.7 10.1 0.47 11.0 2.0 3.2 2 1 0 2 2 2 0 Stc1 domain zinc_ribbon_6 PF14599.6 EGC29560.1 - 0.36 10.9 0.1 0.36 10.9 0.1 3.7 5 0 0 5 5 5 0 Zinc-ribbon DNA_RNApol_7kD PF03604.13 EGC29560.1 - 0.6 9.8 0.1 0.6 9.8 0.1 3.7 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Anti-TRAP PF15777.5 EGC29560.1 - 0.95 9.5 7.3 1.3 9.0 0.1 3.5 4 0 0 4 4 4 0 Tryptophan RNA-binding attenuator protein inhibitory protein zf-CSL PF05207.13 EGC29561.1 - 0.071 12.8 3.5 0.29 10.9 0.1 2.8 2 0 0 2 2 2 0 CSL zinc finger VAPB_antitox PF02697.14 EGC29561.1 - 0.14 13.0 1.1 0.52 11.1 0.0 2.6 2 0 0 2 2 2 0 Putative antitoxin Ricin_B_lectin PF00652.22 EGC29563.1 - 1.8e-06 28.2 2.1 4e-06 27.1 1.7 1.8 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGC29563.1 - 6.4 7.6 12.2 0.9 10.3 1.7 3.2 3 1 1 4 4 4 0 Ricin-type beta-trefoil lectin domain-like Ras PF00071.22 EGC29564.1 - 9.4e-44 148.9 0.0 1.2e-43 148.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC29564.1 - 2.2e-20 73.1 0.0 4e-20 72.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC29564.1 - 0.00014 21.3 0.0 0.0002 20.9 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC29564.1 - 0.076 12.7 0.0 0.76 9.5 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_RNApol_7kD PF03604.13 EGC29567.1 - 5.2e-07 29.2 1.0 0.0047 16.6 0.1 2.3 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit zf-ribbon_3 PF13248.6 EGC29567.1 - 0.0012 18.1 1.6 1 8.8 0.1 2.4 2 0 0 2 2 2 2 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EGC29567.1 - 0.0013 18.2 0.4 1.1 8.8 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding DUF678 PF05077.12 EGC29567.1 - 0.0015 18.6 1.0 0.47 10.6 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF678) zinc_ribbon_6 PF14599.6 EGC29567.1 - 0.0032 17.4 1.6 0.27 11.3 0.1 2.4 2 0 0 2 2 2 1 Zinc-ribbon Ribosomal_S27e PF01667.17 EGC29567.1 - 0.0035 17.0 1.2 1.3 8.8 0.3 2.3 2 0 0 2 2 2 2 Ribosomal protein S27 Evr1_Alr PF04777.13 EGC29567.1 - 0.0036 17.7 2.8 0.038 14.4 0.4 2.2 1 1 1 2 2 2 1 Erv1 / Alr family ADK_lid PF05191.14 EGC29567.1 - 0.0043 17.0 0.1 1.6 8.7 0.0 2.4 2 0 0 2 2 2 1 Adenylate kinase, active site lid CpXC PF14353.6 EGC29567.1 - 0.0057 16.7 2.4 1.1 9.3 0.2 2.2 1 1 0 2 2 2 2 CpXC protein Zn-ribbon_8 PF09723.10 EGC29567.1 - 0.0075 16.4 0.2 3.6 7.8 0.0 2.5 2 0 0 2 2 2 1 Zinc ribbon domain Vps36-NZF-N PF16988.5 EGC29567.1 - 0.0086 15.5 0.5 0.13 11.7 0.1 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting 36 NZF-N zinc-finger domain Stc1 PF12898.7 EGC29567.1 - 0.0088 16.6 1.7 3.4 8.3 0.2 2.3 2 0 0 2 2 2 2 Stc1 domain zf-TRAF PF02176.18 EGC29567.1 - 0.064 14.0 3.4 0.22 12.2 0.4 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger DUF951 PF06107.11 EGC29567.1 - 0.075 13.0 1.2 4.2 7.4 0.2 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zf_UBZ PF18439.1 EGC29567.1 - 0.079 12.6 1.5 2.8 7.6 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf_C2HC_14 PF18574.1 EGC29567.1 - 0.082 12.7 6.5 0.6 9.9 0.7 2.6 2 0 0 2 2 2 0 C2HC Zing finger domain zinc_ribbon_4 PF13717.6 EGC29567.1 - 0.088 12.7 3.1 6 6.9 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EGC29567.1 - 0.11 12.5 2.9 1.4 9.1 2.9 2.1 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_3 PF13878.6 EGC29567.1 - 0.16 11.8 2.7 12 5.8 0.2 2.4 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO Mu-like_Com PF10122.9 EGC29567.1 - 0.33 10.4 1.8 5.4 6.6 0.2 2.2 2 0 0 2 2 2 0 Mu-like prophage protein Com zf-BED PF02892.15 EGC29567.1 - 0.43 10.6 7.9 4.2 7.5 0.7 2.5 2 1 0 2 2 2 0 BED zinc finger HECT_2 PF09814.9 EGC29567.1 - 0.63 8.8 5.7 0.21 10.4 0.6 1.9 1 1 1 2 2 2 0 HECT-like Ubiquitin-conjugating enzyme (E2)-binding Elf1 PF05129.13 EGC29567.1 - 0.84 9.7 6.7 2.8 8.0 1.0 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like zf-CCHC_6 PF15288.6 EGC29567.1 - 1.5 8.8 7.1 10 6.0 0.8 2.4 2 0 0 2 2 2 0 Zinc knuckle Tnp_zf-ribbon_2 PF13842.6 EGC29567.1 - 1.5 9.7 8.8 9.7 7.1 0.7 2.5 2 1 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Zn_ribbon_recom PF13408.6 EGC29567.1 - 2.5 8.7 11.4 2.3 8.8 1.1 3.4 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain zf-ACC PF17848.1 EGC29567.1 - 5.4 7.2 7.9 18 5.5 0.8 2.6 2 0 0 2 2 2 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_2 PF13240.6 EGC29567.1 - 5.5 6.9 8.6 9.1 6.2 0.6 2.4 2 0 0 2 2 2 0 zinc-ribbon domain RasGEF PF00617.19 EGC29568.1 - 5.1e-56 189.7 0.6 5.1e-56 189.7 0.6 2.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC29568.1 - 2e-19 69.7 0.5 2e-19 69.7 0.5 4.1 3 2 0 3 3 3 1 RasGEF N-terminal motif GTP_EFTU PF00009.27 EGC29569.1 - 1.5e-55 187.8 0.2 2.3e-55 187.2 0.2 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGC29569.1 - 6.1e-21 74.3 0.0 1.7e-20 72.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC29569.1 - 1.1e-07 32.1 2.9 1.1e-06 29.0 1.3 3.0 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC29569.1 - 6.8e-07 29.4 0.1 2e-06 27.9 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGC29569.1 - 0.00054 19.3 0.1 0.0013 18.1 0.1 1.6 1 0 0 1 1 1 1 Septin SRPRB PF09439.10 EGC29569.1 - 0.00097 18.6 0.0 0.0028 17.1 0.0 1.9 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.6 EGC29569.1 - 0.0019 18.3 0.0 0.0042 17.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.18 EGC29569.1 - 0.0069 15.9 0.1 0.069 12.7 0.0 2.5 2 1 0 2 2 2 1 Ferrous iron transport protein B TamB PF04357.13 EGC29569.1 - 0.036 13.3 0.0 0.074 12.3 0.0 1.5 1 0 0 1 1 1 0 TamB, inner membrane protein subunit of TAM complex Roc PF08477.13 EGC29569.1 - 0.06 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase ubiquitin PF00240.23 EGC29570.1 - 1.9e-10 40.3 0.0 4.1e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC29570.1 - 0.009 15.8 0.1 0.018 14.9 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC29570.1 - 0.084 13.4 0.0 0.27 11.8 0.0 1.8 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain RabGAP-TBC PF00566.18 EGC29571.1 - 1.1e-48 165.8 4.1 1.1e-48 165.8 4.1 4.1 3 2 1 4 4 4 1 Rab-GTPase-TBC domain EF-hand_6 PF13405.6 EGC29571.1 - 4.9e-10 38.5 1.6 2.8e-05 23.7 0.2 3.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGC29571.1 - 1.5e-09 36.7 4.4 1.4e-05 24.3 0.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGC29571.1 - 3e-08 34.0 2.9 0.00053 20.4 0.1 3.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC29571.1 - 1.1e-05 24.7 5.4 1.5e-05 24.3 0.3 3.2 3 0 0 3 3 3 1 EF hand EF-hand_8 PF13833.6 EGC29571.1 - 0.0009 19.0 3.3 0.065 13.1 0.2 3.3 2 1 1 3 3 3 2 EF-hand domain pair KTSC PF13619.6 EGC29572.1 - 0.0012 18.6 0.2 0.0045 16.8 0.2 2.0 1 0 0 1 1 1 1 KTSC domain NDK PF00334.19 EGC29573.1 - 2.1e-50 170.3 0.0 3.1e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PHP PF02811.19 EGC29574.1 - 7.6e-05 23.1 0.0 0.0001 22.7 0.0 1.4 1 1 0 1 1 1 1 PHP domain Ost4 PF10215.9 EGC29574.1 - 0.14 12.0 1.2 0.38 10.6 1.2 1.8 1 0 0 1 1 1 0 Oligosaccaryltransferase zf-RING_2 PF13639.6 EGC29575.1 - 7.4e-09 35.8 17.2 1.4e-08 34.9 17.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29575.1 - 6.1e-08 32.4 14.8 1e-07 31.7 14.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29575.1 - 5.1e-06 26.2 16.0 9.7e-06 25.3 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29575.1 - 0.0001 22.5 13.1 0.0001 22.5 13.1 2.3 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC29575.1 - 0.00015 21.5 15.4 0.0008 19.2 15.1 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC29575.1 - 0.00021 21.1 18.9 0.00045 20.0 18.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29575.1 - 0.014 15.4 9.7 0.022 14.8 8.6 2.0 1 1 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGC29575.1 - 0.02 14.8 16.8 0.047 13.6 16.8 1.7 1 0 0 1 1 1 0 zinc-RING finger domain TFIIA PF03153.13 EGC29575.1 - 0.057 13.4 68.0 0.15 12.0 26.9 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 EGC29575.1 - 0.4 10.5 11.7 0.88 9.4 11.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC29575.1 - 4.7 7.5 14.9 17 5.7 14.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGC29575.1 - 6.9 6.4 11.9 12 5.6 11.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Erf4 PF10256.9 EGC29576.1 - 0.11 12.6 7.6 2.9 8.0 0.5 3.7 2 2 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family EGF_2 PF07974.13 EGC29577.1 - 0.096 13.1 13.8 0.26 11.7 13.8 1.8 1 0 0 1 1 1 0 EGF-like domain NICE-1 PF15845.5 EGC29577.1 - 0.3 11.9 4.3 0.74 10.6 4.3 1.6 1 0 0 1 1 1 0 Cysteine-rich C-terminal 1 family zf-TRAF PF02176.18 EGC29578.1 - 9.3e-05 23.0 2.5 9.3e-05 23.0 2.5 3.3 3 1 1 4 4 4 2 TRAF-type zinc finger DpnI PF06044.12 EGC29578.1 - 0.0052 16.4 2.5 0.0052 16.4 2.5 1.6 2 1 0 2 2 2 1 Dam-replacing family DM PF00751.18 EGC29578.1 - 0.031 14.2 0.8 0.031 14.2 0.8 3.5 2 2 1 3 3 3 0 DM DNA binding domain Sina PF03145.16 EGC29578.1 - 0.061 13.3 13.2 0.081 12.9 0.3 2.9 2 1 1 3 3 3 0 Seven in absentia protein family zf_C2HC_14 PF18574.1 EGC29578.1 - 0.18 11.6 0.1 0.18 11.6 0.1 3.8 4 0 0 4 4 4 0 C2HC Zing finger domain zf-TRAF_2 PF15965.5 EGC29578.1 - 0.39 11.2 13.4 0.25 11.8 10.4 2.3 1 1 0 1 1 1 0 TRAF-like zinc-finger Prok-RING_2 PF14445.6 EGC29578.1 - 0.99 9.6 8.3 0.44 10.7 4.2 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 CwfJ_C_1 PF04677.15 EGC29579.1 - 4.6e-34 116.9 0.4 1e-33 115.8 0.4 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGC29579.1 - 5.4e-24 85.0 0.3 5.4e-24 85.0 0.3 3.9 3 0 0 3 3 3 1 Protein similar to CwfJ C-terminus 2 Stealth_CR2 PF11380.8 EGC29580.1 - 6.9e-34 116.3 3.3 6.9e-34 116.3 3.3 3.0 2 1 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 EGC29580.1 - 1.5e-10 40.6 0.2 1.9e-09 37.1 0.0 2.7 3 0 0 3 3 3 1 Stealth protein CR1, conserved region 1 Stealth_CR3 PF17102.5 EGC29580.1 - 1.1e-07 31.7 0.3 2.2e-07 30.6 0.0 1.7 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 IGR PF09597.10 EGC29580.1 - 0.091 12.9 0.0 0.25 11.4 0.0 1.7 1 0 0 1 1 1 0 IGR protein motif PAH PF02671.21 EGC29581.1 - 0.0062 16.6 0.5 0.014 15.5 0.4 1.8 1 1 0 1 1 1 1 Paired amphipathic helix repeat Acyl_transf_1 PF00698.21 EGC29583.1 - 3.7e-12 46.4 0.0 4.4e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 Acyl transferase domain IFN-gamma PF00714.17 EGC29583.1 - 0.077 12.8 2.0 0.22 11.4 0.2 2.6 2 1 1 3 3 3 0 Interferon gamma DUF812 PF05667.11 EGC29584.1 - 1.3e-172 575.8 35.1 1.6e-172 575.5 35.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) MCC-bdg_PDZ PF10506.9 EGC29584.1 - 0.73 9.9 9.5 0.039 14.0 1.5 2.9 3 0 0 3 3 3 0 PDZ domain of MCC-2 bdg protein for Usher syndrome ANAPC4 PF12896.7 EGC29584.1 - 0.78 9.2 17.2 0.072 12.6 0.4 4.4 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 4 DUF3734 PF12536.8 EGC29584.1 - 1.5 9.2 10.7 4.4 7.7 0.9 3.1 2 0 0 2 2 2 0 Patatin phospholipase LPP PF04728.13 EGC29584.1 - 3.8 8.0 20.4 1.6 9.2 2.0 5.1 4 1 0 4 4 4 0 Lipoprotein leucine-zipper Csm2_III-A PF03750.13 EGC29584.1 - 4.4 8.2 17.5 3.4 8.5 2.1 4.3 3 1 0 3 3 3 0 Csm2 Type III-A Tropomyosin_1 PF12718.7 EGC29584.1 - 6 7.0 45.4 2 8.6 22.1 3.5 1 1 3 4 4 4 0 Tropomyosin like PNKP_ligase PF16542.5 EGC29584.1 - 9.3 5.6 12.2 1.8 8.0 2.4 2.4 1 1 0 2 2 2 0 PNKP adenylyltransferase domain, ligase domain ThiF PF00899.21 EGC29585.1 - 2.7e-23 82.6 0.1 5.2e-23 81.7 0.1 1.4 1 1 0 1 1 1 1 ThiF family ATPase PF06745.13 EGC29585.1 - 0.042 13.2 0.4 0.82 9.0 0.1 2.2 2 0 0 2 2 2 0 KaiC E1_4HB PF16191.5 EGC29585.1 - 0.1 12.8 0.1 0.47 10.7 0.0 2.2 2 0 0 2 2 2 0 Ubiquitin-activating enzyme E1 four-helix bundle TMEM126 PF07114.11 EGC29585.1 - 0.17 11.3 0.0 0.39 10.1 0.0 1.6 1 0 0 1 1 1 0 Transmembrane protein 126 Mito_carr PF00153.27 EGC29587.1 - 2.4e-60 200.5 9.9 1.6e-21 76.0 0.1 4.2 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF1514 PF07438.11 EGC29587.1 - 0.14 12.1 0.0 28 4.7 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) TMEM135_C_rich PF15982.5 EGC29588.1 - 2.1e-27 96.4 0.9 3.3e-27 95.7 0.9 1.3 1 0 0 1 1 1 1 N-terminal cysteine-rich region of Transmembrane protein 135 5TM-5TMR_LYT PF07694.12 EGC29588.1 - 0.0026 17.3 0.6 0.004 16.7 0.6 1.3 1 0 0 1 1 1 1 5TMR of 5TMR-LYT Tim17 PF02466.19 EGC29588.1 - 0.0056 17.0 0.2 0.0096 16.3 0.1 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0254 PF06787.11 EGC29588.1 - 0.043 13.6 0.0 0.06 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) MgtE PF01769.16 EGC29589.1 - 0.27 11.6 5.5 1.1 9.6 1.3 2.1 2 0 0 2 2 2 0 Divalent cation transporter Stealth_CR2 PF11380.8 EGC29590.1 - 3e-46 156.0 0.4 1.3e-45 154.0 0.1 2.4 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR4 PF17103.5 EGC29590.1 - 3.1e-21 75.0 0.7 1.4e-20 72.9 0.2 2.5 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 EGC29590.1 - 1.5e-17 63.2 4.8 2.8e-17 62.3 4.8 1.5 1 0 0 1 1 1 1 Stealth protein CR3, conserved region 3 Notch PF00066.17 EGC29590.1 - 1.1e-12 48.1 37.8 1.1e-06 28.9 14.5 2.5 2 0 0 2 2 2 2 LNR domain Stealth_CR1 PF17101.5 EGC29590.1 - 1.8e-10 40.3 0.1 4.6e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Methyltransf_16 PF10294.9 EGC29592.1 - 1e-12 48.1 2.3 1.8e-07 31.0 0.2 2.2 1 1 1 2 2 2 2 Lysine methyltransferase Agenet PF05641.12 EGC29592.1 - 0.21 12.1 1.5 0.42 11.1 0.2 2.2 2 1 0 2 2 2 0 Agenet domain Methyltransf_12 PF08242.12 EGC29592.1 - 0.82 10.5 9.4 1.4 9.7 5.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain COMM_domain PF07258.14 EGC29593.1 - 3.7e-16 59.0 0.4 1e-15 57.6 0.3 1.8 2 0 0 2 2 2 1 COMM domain K-box PF01486.17 EGC29593.1 - 0.0096 16.1 0.1 0.033 14.4 0.1 1.9 2 0 0 2 2 2 1 K-box region EF-hand_6 PF13405.6 EGC29594.1 - 2e-18 64.7 8.0 1.8e-06 27.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC29594.1 - 7.6e-18 62.7 11.0 4.5e-06 25.8 0.1 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC29594.1 - 1.5e-17 63.8 14.0 2.2e-09 37.6 2.9 2.9 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC29594.1 - 9.9e-11 40.6 12.6 6.5e-06 25.4 0.1 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGC29594.1 - 2.2e-10 40.2 4.2 8.9e-07 28.7 0.6 4.2 2 1 2 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EGC29594.1 - 0.00046 20.1 4.5 0.0039 17.1 0.5 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGC29594.1 - 0.0013 19.0 4.4 1.2 9.5 0.3 2.9 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_11 PF08976.11 EGC29594.1 - 0.0054 17.6 0.7 2.5 9.0 0.1 2.9 2 1 1 3 3 3 1 EF-hand domain EF-hand_9 PF14658.6 EGC29594.1 - 0.006 16.9 0.1 0.016 15.5 0.0 1.7 2 0 0 2 2 2 1 EF-hand domain Peptidase_S46 PF10459.9 EGC29594.1 - 0.12 11.0 0.5 0.14 10.8 0.5 1.1 1 0 0 1 1 1 0 Peptidase S46 EF-hand_10 PF14788.6 EGC29594.1 - 0.15 11.9 9.7 0.52 10.2 0.8 3.7 4 1 0 4 4 4 0 EF hand Caleosin PF05042.13 EGC29594.1 - 0.51 10.2 5.6 2.8 7.8 0.0 3.0 1 1 2 3 3 3 0 Caleosin related protein AMP-binding PF00501.28 EGC29595.1 - 1.8e-67 227.8 0.0 2.3e-67 227.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC29595.1 - 5.8e-12 45.3 2.9 1.1e-11 44.5 2.9 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC29595.1 - 5.3e-07 30.5 0.0 1.1e-06 29.5 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-TRAF_2 PF15965.5 EGC29597.1 - 0.052 14.0 2.2 0.11 13.0 2.2 1.4 1 0 0 1 1 1 0 TRAF-like zinc-finger VPS13 PF16908.5 EGC29598.1 - 1.9e-68 230.8 1.1 1.9e-68 230.8 1.1 6.3 6 1 1 7 7 7 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EGC29598.1 - 4.6e-39 134.2 26.6 2.9e-36 125.1 7.9 9.0 6 2 0 6 6 6 2 Repeating coiled region of VPS13 Chorein_N PF12624.7 EGC29598.1 - 3.3e-36 123.9 3.9 3.3e-36 123.9 3.9 8.9 10 1 0 10 10 10 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGC29598.1 - 1.1e-32 113.3 7.6 1e-31 110.1 0.1 4.7 3 0 0 3 3 3 1 Vacuolar-sorting-associated 13 protein C-terminal ATG_C PF09333.11 EGC29598.1 - 1.7e-11 44.3 0.0 1.3e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain GCD14 PF08704.10 EGC29601.1 - 1.8e-102 342.2 0.0 2.3e-102 341.9 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit GCD14_N PF14801.6 EGC29601.1 - 8.5e-08 31.9 0.0 1.8e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit N-term Methyltransf_31 PF13847.6 EGC29601.1 - 1.5e-07 31.4 0.0 2.2e-07 30.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGC29601.1 - 3.8e-06 26.8 0.0 7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_24 PF13578.6 EGC29601.1 - 0.0002 22.4 0.0 0.00033 21.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29601.1 - 0.00053 20.6 0.0 0.0011 19.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Fibrillarin PF01269.17 EGC29601.1 - 0.00071 18.8 0.0 0.0023 17.1 0.0 1.8 1 1 0 1 1 1 1 Fibrillarin MTS PF05175.14 EGC29601.1 - 0.0033 17.0 0.0 0.0058 16.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EGC29601.1 - 0.007 15.5 0.0 0.012 14.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PrmA PF06325.13 EGC29601.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_3 PF01596.17 EGC29601.1 - 0.013 14.7 0.0 0.047 12.8 0.0 1.8 2 0 0 2 2 2 0 O-methyltransferase Ubie_methyltran PF01209.18 EGC29601.1 - 0.031 13.6 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF4715 PF15835.5 EGC29601.1 - 0.16 12.1 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4715) MMR_HSR1 PF01926.23 EGC29602.1 - 1.1e-13 51.2 0.1 4.9e-13 49.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC29602.1 - 2.4e-05 23.9 0.5 6.2e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC29602.1 - 0.00096 19.1 0.2 0.026 14.4 0.0 2.9 3 0 0 3 3 3 1 RsgA GTPase MAP17 PF15807.5 EGC29603.1 - 0.075 13.3 0.1 0.075 13.3 0.1 2.9 2 1 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 FAM176 PF14851.6 EGC29603.1 - 0.1 12.3 0.0 0.1 12.3 0.0 3.0 2 1 0 2 2 2 0 FAM176 family Thioredoxin PF00085.20 EGC29604.1 - 7.6e-52 173.6 4.6 1.2e-26 92.7 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.6 EGC29604.1 - 1.7e-34 119.3 11.6 4.1e-31 108.3 2.5 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC29604.1 - 1.4e-11 44.3 2.7 0.00078 18.9 0.0 3.4 2 1 1 3 3 3 3 OST3 / OST6 family, transporter family Calsequestrin PF01216.17 EGC29604.1 - 2.9e-10 39.7 4.6 2.9e-10 39.7 4.6 1.6 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_8 PF13905.6 EGC29604.1 - 9e-08 32.3 2.9 0.0049 17.2 0.0 4.6 3 2 1 4 4 4 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGC29604.1 - 1.1e-07 31.9 0.5 0.042 14.0 0.1 3.7 3 1 0 3 3 3 2 Thioredoxin-like Thioredoxin_2 PF13098.6 EGC29604.1 - 3.7e-05 24.1 4.1 0.23 11.9 0.1 3.7 2 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_9 PF14595.6 EGC29604.1 - 0.0027 17.5 0.1 2.6 7.8 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Glutaredoxin PF00462.24 EGC29604.1 - 0.0064 16.7 0.8 0.78 10.0 0.0 3.0 2 1 0 2 2 2 1 Glutaredoxin TraF PF13728.6 EGC29604.1 - 0.074 12.9 0.1 0.47 10.2 0.0 2.3 2 1 0 2 2 2 0 F plasmid transfer operon protein DUF1936 PF09151.10 EGC29604.1 - 0.11 12.5 0.1 0.43 10.5 0.1 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF1936) Thioredoxin_5 PF13743.6 EGC29604.1 - 0.82 9.3 5.5 11 5.7 0.1 3.8 2 2 2 4 4 4 0 Thioredoxin M16C_assoc PF08367.11 EGC29605.1 - 1.4e-65 220.9 1.3 2.8e-65 219.9 1.3 1.6 1 0 0 1 1 1 1 Peptidase M16C associated Peptidase_M16_C PF05193.21 EGC29605.1 - 2.2e-25 89.8 0.6 4.2e-17 62.8 0.2 3.0 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC29605.1 - 2e-08 34.3 2.7 2.6e-08 34.0 0.0 2.6 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Imm70 PF15601.6 EGC29605.1 - 0.22 11.1 2.4 0.5 9.9 0.8 2.5 3 0 0 3 3 3 0 Immunity protein 70 Phage_TAC_5 PF08890.11 EGC29605.1 - 0.79 9.7 0.0 0.79 9.7 0.0 3.9 4 0 0 4 4 4 0 Phage XkdN-like tail assembly chaperone protein, TAC TMPIT PF07851.13 EGC29605.1 - 2.3 7.4 6.3 3.8 6.7 6.3 1.3 1 0 0 1 1 1 0 TMPIT-like protein VKG_Carbox PF05090.14 EGC29606.1 - 1.1e-07 31.0 15.1 1.8e-07 30.4 15.1 1.4 1 0 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase Bap31 PF05529.12 EGC29606.1 - 0.076 12.9 5.7 1.9 8.4 0.1 3.0 3 0 0 3 3 3 0 Bap31/Bap29 transmembrane region Mucin PF01456.17 EGC29607.1 - 2.8 7.9 14.2 2.1 8.3 1.6 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3053 PF11254.8 EGC29608.1 - 0.023 14.3 0.0 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF3053 PF11254.8 EGC29609.1 - 0.039 13.5 0.0 0.043 13.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Fer4_10 PF13237.6 EGC29610.1 - 0.04 14.0 1.4 1.3 9.2 0.1 3.0 2 0 0 2 2 2 0 4Fe-4S dicluster domain zf-primase PF09329.11 EGC29610.1 - 1.8 8.4 4.6 11 5.9 0.7 2.9 2 0 0 2 2 2 0 Primase zinc finger DUF4611 PF15387.6 EGC29610.1 - 3.1 8.1 13.8 7.6 6.8 1.3 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) OrsD PF12013.8 EGC29610.1 - 3.5 8.1 6.4 1.1 9.8 0.0 3.1 3 0 0 3 3 3 0 Orsellinic acid/F9775 biosynthesis cluster protein D FAM176 PF14851.6 EGC29610.1 - 4.4 7.0 11.1 6.5 6.4 0.7 2.7 2 0 0 2 2 2 0 FAM176 family EphA2_TM PF14575.6 EGC29612.1 - 0.0012 19.7 0.4 2.6 9.0 0.0 2.5 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain DUF4834 PF16118.5 EGC29612.1 - 0.0088 17.0 10.0 0.16 13.0 1.6 2.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4834) GPDPase_memb PF10110.9 EGC29612.1 - 0.02 13.7 0.9 0.02 13.7 0.9 1.8 2 0 0 2 2 2 0 Membrane domain of glycerophosphoryl diester phosphodiesterase ATAD4 PF15321.6 EGC29612.1 - 0.082 14.3 2.2 0.26 12.7 2.2 1.8 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 MscL PF01741.18 EGC29612.1 - 0.094 13.0 1.5 0.18 12.1 0.3 2.1 2 0 0 2 2 2 0 Large-conductance mechanosensitive channel, MscL GRP PF07172.11 EGC29612.1 - 0.17 12.6 0.2 7.6 7.3 0.1 2.4 2 0 0 2 2 2 0 Glycine rich protein family Tetraspanin PF00335.20 EGC29612.1 - 0.17 11.5 3.4 2.5 7.7 0.5 2.7 2 1 0 2 2 2 0 Tetraspanin family OAD_gamma PF04277.13 EGC29612.1 - 0.22 12.1 1.3 25 5.5 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MAP17 PF15807.5 EGC29612.1 - 0.41 10.9 3.1 9.3 6.5 0.2 2.5 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TMEM154 PF15102.6 EGC29612.1 - 0.48 10.3 11.6 0.22 11.5 0.8 2.9 2 1 0 2 2 2 0 TMEM154 protein family DUF4446 PF14584.6 EGC29612.1 - 0.64 10.0 6.0 4.9 7.1 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF3377 PF11857.8 EGC29612.1 - 1.2 9.1 6.8 1.3 9.0 3.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) FeoB_associated PF12669.7 EGC29612.1 - 1.7 9.1 5.4 6.4 7.3 4.2 2.3 2 0 0 2 2 2 0 FeoB-associated Cys-rich membrane protein DUF4064 PF13273.6 EGC29612.1 - 5 7.5 7.7 9.1 6.6 2.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Mu-like_gpT PF10124.9 EGC29613.1 - 0.14 11.5 5.6 0.22 10.8 3.4 2.1 2 0 0 2 2 2 0 Mu-like prophage major head subunit gpT GCD14 PF08704.10 EGC29614.1 - 0.28 10.8 16.1 0.085 12.5 1.2 3.2 3 0 0 3 3 3 0 tRNA methyltransferase complex GCD14 subunit SUIM_assoc PF16619.5 EGC29614.1 - 0.35 11.0 14.5 0.19 11.8 6.1 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF3464 PF11947.8 EGC29614.1 - 0.92 9.2 9.9 0.15 11.8 1.2 2.6 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 Pex2_Pex12 PF04757.14 EGC29614.1 - 3.1 7.3 10.6 0.19 11.3 0.4 3.3 3 0 0 3 3 3 0 Pex2 / Pex12 amino terminal region GNAT_acetyltr_2 PF13718.6 EGC29614.1 - 5.5 6.3 8.9 0.5 9.7 0.1 2.8 3 0 0 3 3 3 0 GNAT acetyltransferase 2 Androgen_recep PF02166.16 EGC29614.1 - 7.6 5.3 10.7 13 4.5 10.7 1.3 1 0 0 1 1 1 0 Androgen receptor Beta-lactamase PF00144.24 EGC29616.1 - 6e-37 127.6 0.0 7.9e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EGC29616.1 - 0.003 17.0 0.0 0.077 12.4 0.0 2.2 2 0 0 2 2 2 1 D-alanyl-D-alanine carboxypeptidase MaoC_dehydratas PF01575.19 EGC29617.1 - 4.2e-20 71.6 0.0 4.7e-20 71.4 0.0 1.0 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.6 EGC29617.1 - 8.1e-05 22.8 0.0 0.00011 22.4 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TIG PF01833.24 EGC29618.1 - 3.5e-16 59.1 16.8 1.7e-05 24.8 0.2 4.7 4 0 0 4 4 4 3 IPT/TIG domain LRR_8 PF13855.6 EGC29618.1 - 7.8e-10 38.4 27.9 0.00072 19.3 0.0 5.0 2 1 1 4 4 4 3 Leucine rich repeat LRR_4 PF12799.7 EGC29618.1 - 4.9e-05 23.6 14.9 0.0058 17.0 0.8 6.3 2 1 4 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC29618.1 - 0.00084 19.6 21.3 15 6.6 0.2 9.0 7 0 0 7 7 7 1 Leucine Rich Repeat LRR_6 PF13516.6 EGC29618.1 - 0.13 12.3 30.4 2.1 8.6 0.5 7.8 8 0 0 8 8 8 0 Leucine Rich repeat ketoacyl-synt PF00109.26 EGC29619.1 - 1e-48 166.1 0.0 1.4e-48 165.7 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC29619.1 - 2.5e-26 92.0 0.0 6.1e-26 90.8 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGC29619.1 - 0.00013 22.4 0.9 0.00042 20.7 0.4 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EGC29619.1 - 0.0097 15.3 0.1 0.017 14.5 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain CTK3 PF12243.8 EGC29619.1 - 0.037 14.0 1.4 0.12 12.4 1.4 1.8 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 VKG_Carbox PF05090.14 EGC29620.1 - 6e-12 45.1 19.2 6e-12 45.1 19.2 2.0 1 1 1 2 2 2 1 Vitamin K-dependent gamma-carboxylase TPR_8 PF13181.6 EGC29620.1 - 0.023 14.9 1.9 0.15 12.3 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC29620.1 - 0.044 13.9 0.1 0.21 11.8 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat CotJB PF12652.7 EGC29620.1 - 0.16 12.2 0.1 0.16 12.2 0.1 2.0 2 0 0 2 2 2 0 CotJB protein FAD_binding_7 PF03441.14 EGC29621.1 - 0.036 13.5 0.1 0.043 13.3 0.1 1.2 1 0 0 1 1 1 0 FAD binding domain of DNA photolyase Ank_2 PF12796.7 EGC29622.1 - 0.053 14.1 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC29622.1 - 0.12 13.0 0.1 1.6 9.4 0.0 2.5 2 1 0 2 2 2 0 Ankyrin repeats (many copies) TBK1_ULD PF18396.1 EGC29623.1 - 0.017 15.1 2.2 0.021 14.7 0.5 2.0 2 0 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain DUF3899 PF13038.6 EGC29623.1 - 0.3 11.6 0.0 0.3 11.6 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) p450 PF00067.22 EGC29624.1 - 7.5e-86 288.7 0.0 8.7e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1_like PF12832.7 EGC29625.1 - 2.1e-62 211.2 17.8 3.8e-62 210.4 17.8 1.4 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGC29625.1 - 4.8e-23 81.7 17.9 1.4e-19 70.3 10.8 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGC29625.1 - 1.6e-08 34.0 32.6 9e-05 21.6 10.0 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter DUF1772 PF08592.11 EGC29625.1 - 0.00096 19.5 0.1 0.5 10.7 0.1 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1772) Zip PF02535.22 EGC29625.1 - 0.0036 16.6 2.4 0.012 14.9 0.0 2.6 3 0 0 3 3 3 1 ZIP Zinc transporter DUF3578 PF12102.8 EGC29625.1 - 0.0081 15.8 0.3 0.029 13.9 0.3 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF3578) DUF2615 PF11027.8 EGC29625.1 - 0.052 13.7 1.7 0.71 10.0 0.2 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) ADH_zinc_N_2 PF13602.6 EGC29626.1 - 1e-17 65.4 0.0 1.6e-17 64.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC29626.1 - 2e-11 43.8 0.0 3.4e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC29626.1 - 3.2e-07 30.4 0.0 7e-07 29.3 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.24 EGC29626.1 - 0.057 13.8 0.0 0.11 12.9 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain ACOX PF01756.19 EGC29627.1 - 2.8e-18 66.1 0.0 6.4e-18 64.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGC29627.1 - 9.7e-16 57.8 0.0 1.8e-15 56.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.6 EGC29627.1 - 1.7e-10 41.6 0.0 2.8e-10 40.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.24 EGC29627.1 - 1.1e-05 25.7 0.0 3.8e-05 23.9 0.0 1.9 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain VWD PF00094.25 EGC29627.1 - 0.046 14.0 0.0 0.1 12.9 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type D domain Acyl-CoA_dh_N PF02771.16 EGC29627.1 - 0.077 13.7 0.0 0.17 12.6 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain JmjN PF02375.17 EGC29627.1 - 0.1 12.6 0.2 29 4.7 0.0 3.4 4 0 0 4 4 4 0 jmjN domain Myotub-related PF06602.14 EGC29628.1 - 6.3e-133 443.1 3.3 6.3e-133 443.1 3.3 2.0 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain PX PF00787.24 EGC29628.1 - 7.4e-16 58.1 4.8 9.3e-16 57.8 2.4 2.4 2 0 0 2 2 2 1 PX domain GRAM PF02893.20 EGC29628.1 - 2.6e-06 27.3 2.0 1.9e-05 24.5 0.5 2.8 2 0 0 2 2 2 1 GRAM domain PH PF00169.29 EGC29628.1 - 1.1e-05 25.8 5.4 1.1e-05 25.8 5.4 4.2 4 2 0 4 4 4 1 PH domain Y_phosphatase3 PF13350.6 EGC29628.1 - 0.0014 18.7 0.0 0.0036 17.3 0.0 1.7 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGC29628.1 - 0.014 15.2 0.6 0.014 15.2 0.6 3.9 3 1 1 4 4 4 0 Dual specificity phosphatase, catalytic domain OTU PF02338.19 EGC29630.1 - 4.3e-12 46.6 0.1 5.5e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4962 PF16332.5 EGC29630.1 - 0.069 11.6 0.5 0.094 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Oxysterol_BP PF01237.18 EGC29631.1 - 3.5e-57 193.9 4.6 5.1e-57 193.4 4.6 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein TSGP1 PF07771.11 EGC29631.1 - 0.6 10.3 7.7 0.36 11.0 1.7 2.3 2 0 0 2 2 2 0 Tick salivary peptide group 1 BRF1 PF07741.13 EGC29631.1 - 1.8 9.0 14.0 0.18 12.1 3.5 2.4 2 0 0 2 2 2 0 Brf1-like TBP-binding domain AP3D1 PF06375.11 EGC29631.1 - 4.5 7.5 15.9 0.26 11.5 6.9 2.2 2 0 0 2 2 2 0 AP-3 complex subunit delta-1 Peptidase_S49_N PF08496.10 EGC29631.1 - 5 7.2 8.7 2.6 8.1 2.5 2.3 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF4419 PF14388.6 EGC29632.1 - 9.5e-91 304.4 0.7 1.1e-90 304.1 0.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) CH PF00307.31 EGC29633.1 - 8.9e-14 51.6 0.1 2.1e-13 50.4 0.1 1.7 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.17 EGC29633.1 - 1.1e-10 41.6 0.7 1.1e-10 41.6 0.7 2.6 2 0 0 2 2 2 1 EB1-like C-terminal motif CAMSAP_CH PF11971.8 EGC29633.1 - 0.00075 19.3 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain T6SS_VasJ PF16989.5 EGC29633.1 - 0.028 13.9 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 Type VI secretion, EvfE, EvfF, ImpA, BimE, VC_A0119, VasJ NPV_P10 PF05531.12 EGC29633.1 - 0.09 13.3 0.1 0.09 13.3 0.1 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein LPP PF04728.13 EGC29633.1 - 0.13 12.7 0.7 0.38 11.2 0.7 1.8 1 0 0 1 1 1 0 Lipoprotein leucine-zipper DUF4140 PF13600.6 EGC29633.1 - 0.25 11.8 0.0 0.25 11.8 0.0 2.9 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) TFIIA PF03153.13 EGC29633.1 - 0.86 9.5 25.8 1.2 9.0 25.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ALMT PF11744.8 EGC29633.1 - 5.4 5.7 8.0 9.5 4.9 8.0 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Cofilin_ADF PF00241.20 EGC29634.1 - 5e-16 58.6 2.6 7.8e-15 54.8 0.0 3.3 3 1 0 3 3 3 1 Cofilin/tropomyosin-type actin-binding protein FMN_red PF03358.15 EGC29635.1 - 4.4e-28 98.0 0.0 7.2e-28 97.3 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.17 EGC29635.1 - 7.3e-05 22.6 0.0 0.0001 22.1 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Dicty_CAR PF05462.11 EGC29636.1 - 2.2e-11 43.5 19.8 2.2e-11 43.5 19.8 1.4 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGC29636.1 - 3.1e-11 43.1 9.4 3.1e-11 43.1 9.4 2.1 1 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) Ocular_alb PF02101.15 EGC29636.1 - 8.5e-06 24.9 11.6 1.6e-05 24.1 11.5 1.5 1 1 0 1 1 1 1 Ocular albinism type 1 protein 7tm_1 PF00001.21 EGC29636.1 - 4.8e-05 22.8 16.6 4.8e-05 22.8 16.6 2.1 1 1 1 2 2 2 1 7 transmembrane receptor (rhodopsin family) UNC-93 PF05978.16 EGC29637.1 - 6.4e-15 55.2 9.5 6.4e-15 55.2 9.5 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.16 EGC29637.1 - 2.3e-14 53.1 28.5 2.3e-14 53.1 28.5 1.7 1 1 0 1 1 1 1 Major Facilitator Superfamily TIG PF01833.24 EGC29638.1 - 9.4e-05 22.4 18.2 0.00011 22.2 3.7 4.8 3 1 1 4 4 4 2 IPT/TIG domain EGF_Tenascin PF18720.1 EGC29638.1 - 0.011 15.8 5.1 0.011 15.8 5.1 2.9 2 0 0 2 2 2 0 Tenascin EGF domain SKG6 PF08693.10 EGC29638.1 - 0.015 14.7 10.9 0.038 13.4 10.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3827 PF12877.7 EGC29638.1 - 0.02 13.3 4.4 0.031 12.7 4.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF_2 PF07974.13 EGC29638.1 - 0.029 14.7 26.0 0.033 14.5 10.5 2.8 2 0 0 2 2 2 0 EGF-like domain EptA_B_N PF08019.12 EGC29638.1 - 0.14 12.0 4.8 0.27 11.1 4.8 1.3 1 0 0 1 1 1 0 Phosphoethanolamine transferase EptA/EptB DUF4448 PF14610.6 EGC29638.1 - 1.7 8.4 7.0 0.23 11.2 1.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EGC29638.1 - 4 7.3 6.6 1.9 8.4 3.6 2.0 2 0 0 2 2 2 0 TMEM154 protein family HECT PF00632.25 EGC29639.1 - 1.2e-71 241.7 1.1 1.2e-71 241.7 1.1 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.19 EGC29639.1 - 1.6e-17 64.2 11.4 2.3e-11 44.4 0.5 3.9 3 0 0 3 3 3 2 Filamin/ABP280 repeat Gemini_AL2 PF01440.16 EGC29639.1 - 0.29 11.6 7.0 0.059 13.8 1.0 3.0 2 0 0 2 2 2 0 Geminivirus AL2 protein TIR-like PF10137.9 EGC29641.1 - 2.5e-08 33.9 0.2 6.9e-08 32.5 0.2 1.8 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain Nefa_Nip30_N PF10187.9 EGC29641.1 - 0.015 15.7 0.9 0.037 14.4 0.9 1.7 1 0 0 1 1 1 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 YL1 PF05764.13 EGC29642.1 - 0.0041 17.3 10.1 0.0041 17.3 10.1 2.6 3 0 0 3 3 3 2 YL1 nuclear protein NanE PF04131.14 EGC29643.1 - 0.2 10.9 0.3 0.39 9.9 0.3 1.4 1 0 0 1 1 1 0 Putative N-acetylmannosamine-6-phosphate epimerase Fer4_17 PF13534.6 EGC29645.1 - 0.056 14.0 1.0 0.056 14.0 1.0 3.0 3 0 0 3 3 3 0 4Fe-4S dicluster domain ComP_DUS PF16732.5 EGC29645.1 - 0.16 12.9 0.2 0.16 12.9 0.2 3.2 4 0 0 4 4 4 0 Type IV minor pilin ComP, DNA uptake sequence receptor CK2S PF15011.6 EGC29646.1 - 0.032 14.1 1.6 4.8 7.0 0.2 2.1 2 0 0 2 2 2 0 Casein Kinase 2 substrate DUF5343 PF17278.2 EGC29646.1 - 0.038 14.1 0.9 0.06 13.4 0.6 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5343) ER PF01133.17 EGC29646.1 - 0.045 13.8 7.8 0.15 12.1 1.0 2.4 1 1 1 2 2 2 0 Enhancer of rudimentary SlyX PF04102.12 EGC29646.1 - 0.097 13.3 0.1 0.2 12.3 0.1 1.5 1 0 0 1 1 1 0 SlyX XisI PF08869.11 EGC29646.1 - 0.15 12.4 2.2 0.14 12.5 0.5 1.8 2 0 0 2 2 2 0 XisI protein RNB PF00773.19 EGC29647.1 - 1.1e-90 304.3 0.0 1.1e-90 304.3 0.0 3.1 3 0 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 EGC29647.1 - 1.8e-17 63.1 0.0 4.5e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_S1 PF17215.3 EGC29647.1 - 6.2e-08 32.5 0.2 2.9e-07 30.4 0.2 2.2 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EGC29647.1 - 1.4e-06 28.1 0.2 5.1e-06 26.3 0.2 2.0 1 0 0 1 1 1 1 Rrp44-like cold shock domain CSD2 PF17876.1 EGC29647.1 - 0.00071 19.7 0.0 0.0049 17.0 0.0 2.6 1 0 0 1 1 1 1 Cold shock domain RNA_Me_trans PF04252.13 EGC29647.1 - 0.12 12.0 2.6 0.3 10.6 2.6 1.7 1 0 0 1 1 1 0 Predicted SAM-dependent RNA methyltransferase SUIM_assoc PF16619.5 EGC29647.1 - 0.91 9.6 17.5 0.078 13.1 5.1 2.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4248 PF14053.6 EGC29648.1 - 0.54 10.3 4.2 1.8 8.6 4.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) RNA_pol_Rbc25 PF08292.12 EGC29648.1 - 1.6 9.0 6.9 0.46 10.7 2.4 2.4 1 1 1 2 2 2 0 RNA polymerase III subunit Rpc25 ZYG-11_interact PF05884.12 EGC29648.1 - 4.9 6.5 6.1 12 5.2 6.1 1.6 1 0 0 1 1 1 0 Interactor of ZYG-11 Lipl32 PF12103.8 EGC29649.1 - 6.6 6.3 8.7 0.25 11.0 1.4 1.8 1 1 1 2 2 2 0 Surface lipoprotein of Spirochaetales order Syntaxin PF00804.25 EGC29652.1 - 0.023 14.4 0.1 0.023 14.4 0.1 1.0 1 0 0 1 1 1 0 Syntaxin SRR PF07709.11 EGC29652.1 - 0.036 14.4 0.2 0.079 13.4 0.0 1.7 2 0 0 2 2 2 0 Seven Residue Repeat Tim44 PF04280.15 EGC29654.1 - 3.3e-07 30.5 0.2 8.6e-07 29.2 0.2 1.6 1 1 0 1 1 1 1 Tim44-like domain DEAD_2 PF06733.15 EGC29655.1 - 2.1e-46 157.7 0.1 3.5e-46 157.0 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.6 EGC29655.1 - 1.6e-30 106.5 0.0 4.1e-30 105.2 0.0 1.7 2 0 0 2 2 2 1 Helicase C-terminal domain ResIII PF04851.15 EGC29655.1 - 8.6e-08 32.4 0.0 5.4e-07 29.8 0.0 2.2 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC29655.1 - 1e-05 25.4 0.0 0.0018 18.1 0.0 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase SNF2_N PF00176.23 EGC29655.1 - 0.00029 19.7 0.0 0.00073 18.4 0.0 1.6 1 1 0 1 1 1 1 SNF2 family N-terminal domain AAA_11 PF13086.6 EGC29655.1 - 0.0026 17.6 0.0 0.015 15.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain PhoH PF02562.16 EGC29655.1 - 0.013 15.0 0.0 1.9 7.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein HmuY PF14064.6 EGC29655.1 - 0.035 14.3 0.1 0.07 13.3 0.1 1.4 1 0 0 1 1 1 0 HmuY protein EGF_2 PF07974.13 EGC29656.1 - 4.1e-06 27.0 38.2 0.0013 19.1 18.2 3.0 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC29656.1 - 0.0052 16.9 21.2 0.034 14.3 3.6 2.7 2 0 0 2 2 2 2 Laminin EGF domain EGF_Tenascin PF18720.1 EGC29656.1 - 0.091 12.8 26.0 0.034 14.2 8.5 2.7 2 0 0 2 2 2 0 Tenascin EGF domain Orthoreo_P17 PF07272.11 EGC29656.1 - 0.13 12.3 1.4 0.4 10.7 0.1 2.3 2 0 0 2 2 2 0 Orthoreovirus P17 protein Coiled PF05710.12 EGC29657.1 - 0.096 13.5 6.9 0.1 13.5 6.9 1.1 1 0 0 1 1 1 0 Coiled coil zf-RING_2 PF13639.6 EGC29658.1 - 1.1e-12 48.1 4.4 5.3e-12 45.9 4.4 2.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC29658.1 - 4.2e-09 36.1 3.7 1.4e-08 34.5 3.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29658.1 - 6.2e-07 29.2 3.3 1.4e-06 28.1 3.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC29658.1 - 9.3e-07 28.6 2.0 1.8e-06 27.7 2.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29658.1 - 4.4e-06 26.5 3.1 4.4e-06 26.5 3.1 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC29658.1 - 1.9e-05 24.3 1.4 1.9e-05 24.3 1.4 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC29658.1 - 4.3e-05 23.7 4.6 4.3e-05 23.7 4.6 4.1 3 1 0 3 3 3 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC29658.1 - 0.00062 19.7 4.5 0.00062 19.7 4.5 2.7 2 0 0 2 2 2 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC29658.1 - 0.0032 17.3 4.7 0.011 15.6 4.2 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC29658.1 - 1.8 8.4 5.0 5.1 7.0 4.9 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain VPS13 PF16908.5 EGC29659.1 - 8.3e-66 222.1 27.6 3.1e-65 220.3 7.7 4.8 5 0 0 5 5 5 2 Vacuolar sorting-associated protein 13, N-terminal VPS13_mid_rpt PF16910.5 EGC29659.1 - 1.2e-64 217.9 53.7 3.1e-57 193.7 10.3 6.5 6 1 0 6 6 6 3 Repeating coiled region of VPS13 VPS13_C PF16909.5 EGC29659.1 - 1.9e-58 197.2 10.9 3.9e-55 186.4 0.2 4.2 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGC29659.1 - 8.4e-34 117.2 24.9 4.5e-28 98.4 7.7 5.5 4 1 0 4 4 4 2 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGC29659.1 - 2.2e-27 95.5 1.9 2.2e-27 95.5 1.9 4.3 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGC29659.1 - 1.4e-08 35.0 0.0 9.4e-08 32.3 0.0 2.4 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain CTNNB1_binding PF08347.11 EGC29659.1 - 0.017 15.3 0.3 0.13 12.4 0.3 2.6 1 0 0 1 1 1 0 N-terminal CTNNB1 binding LIN52 PF10044.9 EGC29659.1 - 0.068 13.9 0.8 0.66 10.7 0.1 3.2 2 0 0 2 2 2 0 Retinal tissue protein Pex26 PF07163.12 EGC29659.1 - 0.48 9.7 6.2 0.69 9.2 0.2 2.5 2 0 0 2 2 2 0 Pex26 protein Atrophin-1 PF03154.15 EGC29659.1 - 9.9 4.3 9.8 0.047 12.0 0.2 1.9 2 0 0 2 2 2 0 Atrophin-1 family Pkinase PF00069.25 EGC29660.1 - 1.6e-68 230.9 0.0 1.9e-68 230.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29660.1 - 2.5e-34 118.8 0.0 3.7e-34 118.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC29660.1 - 0.0036 16.3 0.1 0.0053 15.7 0.1 1.3 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC29660.1 - 0.041 13.2 0.2 0.25 10.6 0.0 2.1 2 1 0 2 2 2 0 Kinase-like Imm7 PF15585.6 EGC29660.1 - 0.062 13.6 0.1 1.2 9.5 0.0 2.2 2 0 0 2 2 2 0 Immunity protein 7 Kdo PF06293.14 EGC29660.1 - 0.15 11.4 0.0 0.45 9.8 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family HEAT PF02985.22 EGC29661.1 - 5e-05 23.2 5.6 4.9 7.7 0.1 5.4 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGC29661.1 - 0.003 17.9 0.0 0.59 10.6 0.1 2.7 1 1 1 2 2 2 2 HEAT repeats HycH PF07450.11 EGC29661.1 - 0.034 14.5 1.1 5.1 7.5 0.3 3.8 3 1 0 3 3 3 0 Formate hydrogenlyase maturation protein HycH RIX1 PF08167.12 EGC29661.1 - 0.051 13.3 0.4 0.051 13.3 0.4 2.9 2 1 1 3 3 3 0 rRNA processing/ribosome biogenesis Vac14_Fab1_bd PF12755.7 EGC29661.1 - 0.06 14.0 6.8 3.8 8.2 0.0 5.0 4 1 1 5 5 5 0 Vacuolar 14 Fab1-binding region DUF2164 PF09932.9 EGC29661.1 - 0.064 13.3 0.0 0.27 11.3 0.0 2.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2164) HEAT_EZ PF13513.6 EGC29661.1 - 0.077 13.5 0.2 2.2 8.9 0.3 2.9 1 1 2 3 3 3 0 HEAT-like repeat ParcG PF10274.9 EGC29661.1 - 2.7 8.1 9.4 0.31 11.1 0.5 3.5 3 1 1 4 4 4 0 Parkin co-regulated protein Metallophos PF00149.28 EGC29662.1 - 8.4e-12 46.0 0.2 1.3e-11 45.4 0.2 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase NIF PF03031.18 EGC29663.1 - 1.2e-52 177.8 3.3 1.2e-52 177.8 3.3 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase HAD PF12710.7 EGC29663.1 - 0.03 14.7 0.0 0.33 11.3 0.0 2.0 1 1 1 2 2 2 0 haloacid dehalogenase-like hydrolase UPF0242 PF06785.11 EGC29663.1 - 0.072 13.2 3.6 0.058 13.5 1.9 1.7 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus POP1 PF06978.11 EGC29663.1 - 0.45 10.5 3.9 0.87 9.5 3.9 1.4 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 HAD_2 PF13419.6 EGC29663.1 - 0.67 10.0 5.5 1.2 9.1 0.1 2.7 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase OTU PF02338.19 EGC29667.1 - 4.2e-12 46.7 0.1 5.4e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4962 PF16332.5 EGC29667.1 - 0.069 11.7 0.5 0.093 11.2 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) HTH_32 PF13565.6 EGC29671.1 - 1.1e-07 32.4 0.0 3.2e-07 30.8 0.0 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_23 PF13384.6 EGC29671.1 - 4.6e-07 29.5 0.1 6.9e-06 25.7 0.0 2.4 3 0 0 3 3 3 1 Homeodomain-like domain HTH_38 PF13936.6 EGC29671.1 - 2.7e-06 27.1 0.4 2.7e-06 27.1 0.4 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.6 EGC29671.1 - 5.6e-05 22.7 0.0 0.0001 21.9 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.18 EGC29671.1 - 8.2e-05 22.8 0.7 0.55 10.5 0.0 2.5 2 1 0 2 2 2 2 Transposase HTH_29 PF13551.6 EGC29671.1 - 0.00026 20.9 0.0 0.00056 19.9 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn helix Sigma70_r4_2 PF08281.12 EGC29671.1 - 0.0017 18.0 0.5 0.0084 15.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.15 EGC29671.1 - 0.004 17.2 1.0 0.048 13.8 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase HTH_28 PF13518.6 EGC29671.1 - 0.017 15.2 0.0 0.091 12.9 0.0 2.0 2 1 0 2 2 2 0 Helix-turn-helix domain Menin PF05053.13 EGC29675.1 - 1.9 6.8 7.0 2.2 6.6 7.0 1.0 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.6 EGC29676.1 - 1.6e-11 44.3 9.1 2.8e-11 43.6 9.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29676.1 - 1.6e-08 34.3 6.6 2.4e-08 33.7 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29676.1 - 3.7e-08 33.1 8.5 6.5e-08 32.3 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29676.1 - 4.7e-08 32.8 10.8 9.5e-08 31.8 10.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29676.1 - 1.4e-07 31.7 6.7 4.5e-07 30.1 6.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC29676.1 - 2.8e-06 27.1 5.3 5.9e-06 26.0 5.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC29676.1 - 3.3e-06 26.9 9.2 6.5e-06 26.0 9.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC29676.1 - 4.1e-06 26.7 3.2 6.9e-06 26.0 1.6 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC29676.1 - 0.00068 19.7 9.1 0.0016 18.6 8.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC29676.1 - 0.0053 16.5 11.0 0.011 15.5 11.0 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC29676.1 - 0.0061 16.6 2.0 0.016 15.3 2.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger MAP7 PF05672.11 EGC29676.1 - 0.011 15.5 37.8 0.011 15.5 37.8 2.6 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family zf-RING_10 PF16685.5 EGC29676.1 - 0.018 15.2 3.1 0.043 13.9 3.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGC29676.1 - 0.27 11.0 5.9 0.55 10.0 5.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC29676.1 - 0.81 9.4 6.5 1.4 8.6 6.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 EGC29676.1 - 4.1 7.6 8.1 7.8 6.7 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PA26 PF04636.13 EGC29676.1 - 7.2 5.4 26.8 4.9 6.0 11.0 2.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) RRM_1 PF00076.22 EGC29677.1 - 5e-21 74.3 0.0 7.3e-21 73.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SelP_N PF04592.14 EGC29677.1 - 6.4 6.1 9.7 0.85 9.0 2.8 2.2 2 0 0 2 2 2 0 Selenoprotein P, N terminal region GATA PF00320.27 EGC29678.1 - 6.4e-08 32.1 8.8 1.1e-07 31.4 8.8 1.3 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.27 EGC29679.1 - 0.00092 18.8 0.7 0.0028 17.2 0.7 1.8 1 1 0 1 1 1 1 GATA zinc finger Inhibitor_I71 PF12628.7 EGC29681.1 - 0.029 14.2 0.5 0.034 14.0 0.5 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor GATA PF00320.27 EGC29682.1 - 6.8e-05 22.4 0.5 8.6e-05 22.1 0.5 1.2 1 0 0 1 1 1 1 GATA zinc finger Paired_CXXCH_1 PF09699.10 EGC29682.1 - 0.013 15.3 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 0 Doubled CXXCH motif (Paired_CXXCH_1) GATA PF00320.27 EGC29684.1 - 4.1e-12 45.5 6.3 4.1e-12 45.5 6.3 2.0 2 0 0 2 2 2 1 GATA zinc finger Zn_ribbon_SprT PF17283.2 EGC29684.1 - 0.47 10.4 6.0 8.6 6.4 0.1 3.1 2 1 1 3 3 3 0 SprT-like zinc ribbon domain Coilin_N PF15862.5 EGC29689.1 - 7.3 6.4 7.2 3.4 7.5 0.1 3.0 3 0 0 3 3 3 0 Coilin N-terminus RNase_T PF00929.24 EGC29690.1 - 0.0051 17.4 0.0 0.012 16.2 0.0 1.6 1 0 0 1 1 1 1 Exonuclease Asp-B-Hydro_N PF05279.11 EGC29691.1 - 3.3 7.7 7.7 1.9 8.5 5.5 1.5 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF202 PF02656.15 EGC29692.1 - 7.7e-09 35.9 6.6 7.7e-09 35.9 6.6 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF202) DUF4131 PF13567.6 EGC29692.1 - 0.4 10.3 3.7 0.66 9.6 3.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2207 PF09972.9 EGC29692.1 - 0.53 9.0 10.4 3.4 6.3 10.4 1.9 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SHR3_chaperone PF08229.11 EGC29692.1 - 1.3 7.9 3.5 3.4 6.6 3.6 1.8 1 1 0 1 1 1 0 ER membrane protein SH3 DUF2530 PF10745.9 EGC29692.1 - 9.8 6.5 6.2 21 5.4 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2530) Phospholip_B PF04916.13 EGC29693.1 - 9.3e-167 555.8 17.1 1.1e-166 555.6 17.1 1.0 1 0 0 1 1 1 1 Phospholipase B Exo_endo_phos PF03372.23 EGC29694.1 - 3.3e-22 79.2 0.0 3.7e-22 79.0 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGC29694.1 - 0.00085 19.2 0.0 0.0016 18.3 0.0 1.5 1 1 0 1 1 1 1 Endonuclease-reverse transcriptase SapB_2 PF03489.17 EGC29695.1 - 1.4e-18 66.7 1.0 4.5e-09 36.3 0.3 2.7 2 0 0 2 2 2 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC29695.1 - 5e-16 58.4 3.6 2.3e-11 43.5 0.9 3.8 2 1 0 2 2 2 2 Saposin-like type B, region 1 GBP PF02263.19 EGC29696.1 - 0.012 14.9 0.0 0.032 13.5 0.0 1.7 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain SAC3_GANP PF03399.16 EGC29697.1 - 2.4e-20 73.1 8.3 2.2e-18 66.7 8.3 2.0 1 1 0 1 1 1 1 SAC3/GANP family Prp18 PF02840.15 EGC29697.1 - 0.094 12.8 0.8 0.31 11.1 0.2 2.1 1 1 0 2 2 2 0 Prp18 domain CSN8_PSD8_EIF3K PF10075.9 EGC29697.1 - 0.1 12.6 3.1 0.23 11.5 3.1 1.6 1 0 0 1 1 1 0 CSN8/PSMD8/EIF3K family RasGEF PF00617.19 EGC29698.1 - 5.8e-51 173.2 3.0 2.1e-50 171.4 0.9 2.5 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC29698.1 - 8.8e-10 38.8 0.9 1.5e-08 34.8 0.9 2.7 1 1 0 1 1 1 1 RasGEF N-terminal motif LisH_TPL PF17814.1 EGC29698.1 - 0.0036 16.9 0.3 0.01 15.5 0.3 1.7 1 0 0 1 1 1 1 LisH-like dimerisation domain DUF3987 PF13148.6 EGC29698.1 - 0.14 11.1 0.1 0.31 10.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Tubulin PF00091.25 EGC29699.1 - 7.3e-32 111.2 3.6 7.3e-32 111.2 3.6 2.1 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.8 EGC29699.1 - 1.3e-30 105.5 0.6 3.3e-30 104.2 0.6 1.7 1 0 0 1 1 1 1 FtsZ family, C-terminal domain AMP-binding PF00501.28 EGC29700.1 - 6.7e-90 301.7 0.0 8.1e-90 301.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC29700.1 - 1.6e-20 73.9 0.1 4.1e-20 72.5 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC29700.1 - 1.6e-19 69.5 3.3 1.6e-19 69.5 3.3 2.3 2 1 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus Solute_trans_a PF03619.16 EGC29701.1 - 9.3e-85 284.3 25.2 1.1e-84 284.0 25.2 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF2673 PF10880.8 EGC29702.1 - 0.022 14.9 0.1 0.042 14.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2673) Cyt-b5 PF00173.28 EGC29703.1 - 1.2e-20 73.4 0.1 1.6e-20 73.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thioredoxin PF00085.20 EGC29704.1 - 3.5e-65 216.4 3.6 1.5e-32 111.6 0.4 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.12 EGC29704.1 - 1.2e-26 93.5 1.1 2.6e-26 92.4 1.1 1.6 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain OST3_OST6 PF04756.13 EGC29704.1 - 1.4e-16 60.7 0.3 5e-08 32.6 0.1 2.3 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGC29704.1 - 4.2e-15 56.1 1.6 1e-06 29.1 0.1 2.7 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC29704.1 - 4.8e-13 49.2 0.7 8.6e-05 22.8 0.1 4.6 2 2 2 4 4 4 3 Thioredoxin-like Thioredoxin_7 PF13899.6 EGC29704.1 - 1.5e-09 37.9 0.3 0.00018 21.6 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like ERp29_N PF07912.13 EGC29704.1 - 2.3e-09 37.5 1.7 0.0018 18.4 0.1 2.6 2 0 0 2 2 2 2 ERp29, N-terminal domain AhpC-TSA PF00578.21 EGC29704.1 - 5.1e-09 36.1 0.8 5.4e-05 23.1 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family Thioredoxin_6 PF13848.6 EGC29704.1 - 8.4e-07 29.1 2.5 0.042 13.8 0.1 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Redoxin PF08534.10 EGC29704.1 - 2.7e-06 27.1 4.9 0.019 14.7 0.2 2.9 2 1 1 3 3 3 2 Redoxin TraF PF13728.6 EGC29704.1 - 0.00057 19.8 0.1 0.41 10.4 0.0 2.6 3 0 0 3 3 3 2 F plasmid transfer operon protein IZUMO PF15005.6 EGC29704.1 - 0.022 15.3 1.3 0.15 12.5 0.1 2.7 3 1 0 3 3 3 0 Izumo sperm-egg fusion, Ig domain-associated DDE_Tnp_1_2 PF13586.6 EGC29704.1 - 0.031 14.6 0.0 17 5.8 0.0 3.3 3 1 0 3 3 3 0 Transposase DDE domain HyaE PF07449.11 EGC29704.1 - 0.035 14.1 0.0 11 6.0 0.0 2.6 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE DUF445 PF04286.12 EGC29704.1 - 0.05 13.4 0.8 0.079 12.7 0.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF445) UL11 PF11094.8 EGC29704.1 - 0.11 12.4 0.9 0.45 10.4 0.1 2.3 2 0 0 2 2 2 0 Membrane-associated tegument protein Thioredoxin_4 PF13462.6 EGC29704.1 - 0.65 10.1 5.0 1.9 8.6 0.3 3.2 2 2 1 3 3 3 0 Thioredoxin Pkinase PF00069.25 EGC29705.1 - 1.6e-46 158.9 2.1 2.6e-34 118.8 0.2 5.1 5 1 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29705.1 - 1.2e-24 87.0 0.3 2e-12 46.9 0.0 3.7 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.22 EGC29705.1 - 4.1e-20 72.2 0.6 4.1e-20 72.2 0.6 3.2 2 0 0 2 2 2 1 RWD domain tRNA-synt_His PF13393.6 EGC29705.1 - 1.5e-12 47.4 0.0 1.1e-11 44.6 0.0 2.5 3 1 0 3 3 3 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 EGC29705.1 - 3.4e-10 39.9 0.0 3.4e-10 39.9 0.0 7.1 7 0 0 7 7 7 2 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.20 EGC29705.1 - 2.6e-07 30.7 2.4 1.5e-06 28.3 0.1 3.2 3 0 0 3 3 3 1 Anticodon binding domain Kinase-like PF14531.6 EGC29705.1 - 0.00077 18.9 0.0 0.0088 15.4 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Trypsin_2 PF13365.6 EGC29706.1 - 0.0031 18.4 0.0 0.0048 17.8 0.0 1.3 1 0 0 1 1 1 1 Trypsin-like peptidase domain QWRF PF04484.12 EGC29706.1 - 0.77 9.5 3.9 0.46 10.2 0.4 1.9 2 0 0 2 2 2 0 QWRF family IGR PF09597.10 EGC29707.1 - 5.4e-25 87.3 0.7 1.1e-24 86.3 0.1 1.8 2 0 0 2 2 2 1 IGR protein motif HhH-GPD PF00730.25 EGC29707.1 - 0.1 13.0 0.0 4.9 7.6 0.0 2.3 2 0 0 2 2 2 0 HhH-GPD superfamily base excision DNA repair protein Mal_decarbox_Al PF16957.5 EGC29707.1 - 0.19 10.0 0.1 0.24 9.7 0.1 1.1 1 0 0 1 1 1 0 Malonate decarboxylase, alpha subunit, transporter Ank_5 PF13857.6 EGC29708.1 - 1.2e-14 54.1 0.0 6.4e-08 32.7 0.0 2.9 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC29708.1 - 2.9e-12 46.9 0.0 1.4e-11 44.6 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC29708.1 - 1.2e-11 45.0 0.0 4.2e-11 43.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGC29708.1 - 1.4e-11 44.3 0.0 3.9e-05 23.9 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGC29708.1 - 7.4e-10 38.2 0.0 0.00024 21.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat zf-RING_UBOX PF13445.6 EGC29710.1 - 6.7e-11 42.0 7.7 6.7e-11 42.0 7.7 2.1 2 0 0 2 2 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC29710.1 - 1.1e-08 34.8 4.9 1.1e-08 34.8 4.9 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29710.1 - 5.2e-08 32.6 10.7 5.2e-08 32.6 10.7 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC29710.1 - 8.7e-08 32.2 11.2 8.7e-08 32.2 11.2 2.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGC29710.1 - 1.2e-07 31.9 8.9 1.2e-07 31.9 8.9 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.6 EGC29710.1 - 2.6e-07 30.5 8.4 2.6e-07 30.5 8.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC29710.1 - 4.5e-06 26.4 6.8 4.5e-06 26.4 6.8 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGC29710.1 - 8.1e-06 25.6 9.0 8.1e-06 25.6 9.0 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-B_box PF00643.24 EGC29710.1 - 5.1e-05 23.3 7.3 5.1e-05 23.3 7.3 3.0 3 0 0 3 3 3 1 B-box zinc finger U-box PF04564.15 EGC29710.1 - 0.0012 19.0 0.1 0.013 15.6 0.0 2.4 2 0 0 2 2 2 1 U-box domain zf-RING_11 PF17123.5 EGC29710.1 - 0.078 12.7 5.6 0.31 10.8 5.4 2.2 1 1 1 2 2 2 0 RING-like zinc finger FYVE_2 PF02318.16 EGC29710.1 - 6.9 6.9 15.4 5.1 7.3 1.3 2.5 2 0 0 2 2 2 0 FYVE-type zinc finger DUF4503 PF14951.6 EGC29710.1 - 6.9 5.0 11.4 1.3 7.4 5.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4503) ketoacyl-synt PF00109.26 EGC29711.1 - 4.6e-64 216.4 0.0 7.7e-64 215.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC29711.1 - 7.4e-39 134.1 0.0 1.2e-38 133.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC29711.1 - 9.8e-32 109.4 0.0 5.7e-31 107.0 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC29711.1 - 4e-25 88.8 0.1 1.2e-24 87.2 0.1 1.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC29711.1 - 3e-20 72.7 0.0 4.5e-20 72.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC29711.1 - 9.7e-20 71.2 0.0 9.7e-20 71.2 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC29711.1 - 8.8e-17 61.6 0.1 2.6e-16 60.0 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC29711.1 - 1.5e-09 39.0 0.0 2e-08 35.3 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGC29711.1 - 1.5e-06 28.5 0.1 3.5e-06 27.3 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGC29711.1 - 1.9e-06 27.7 0.1 4.4e-06 26.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC29711.1 - 1.5e-05 24.5 0.0 3.3e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGC29711.1 - 8.7e-05 23.1 0.0 0.00026 21.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC29711.1 - 0.00037 20.4 0.0 0.0011 18.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DUF1430 PF07242.11 EGC29711.1 - 0.00077 19.7 0.8 0.0053 17.0 0.4 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1430) Methyltransf_31 PF13847.6 EGC29711.1 - 0.021 14.6 4.7 0.063 13.1 0.0 3.7 4 0 0 4 4 4 0 Methyltransferase domain Peptidase_S28 PF05577.12 EGC29712.1 - 2.8e-79 267.0 0.3 4.1e-79 266.4 0.3 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S9 PF00326.21 EGC29712.1 - 0.0024 17.4 0.0 0.0059 16.1 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGC29712.1 - 0.0095 15.6 0.0 0.017 14.8 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC29712.1 - 0.01 16.4 0.2 0.042 14.4 0.2 2.0 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S37 PF05576.11 EGC29712.1 - 0.018 13.8 0.0 0.042 12.5 0.0 1.6 1 1 0 1 1 1 0 PS-10 peptidase S37 Hydrolase_4 PF12146.8 EGC29712.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Ku PF02735.16 EGC29713.1 - 1.2e-40 139.4 0.6 4e-40 137.7 0.1 2.1 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_PK_bind PF08785.11 EGC29713.1 - 6.9e-38 129.5 1.8 3.4e-37 127.2 1.8 2.3 1 0 0 1 1 1 1 Ku C terminal domain like Ku_N PF03731.15 EGC29713.1 - 1.1e-23 84.1 3.6 2.8e-23 82.8 3.6 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGC29713.1 - 3.5e-08 34.0 3.3 4.9e-08 33.6 0.9 2.5 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SBP_bac_5 PF00496.22 EGC29713.1 - 0.0041 16.1 1.5 0.0072 15.3 0.1 2.0 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 5 Middle MGS PF02142.22 EGC29713.1 - 0.033 14.4 0.1 0.099 12.8 0.1 1.8 1 0 0 1 1 1 0 MGS-like domain TatD_DNase PF01026.21 EGC29715.1 - 2.3e-49 168.1 0.0 2.6e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase TIG PF01833.24 EGC29717.1 - 6.1e-06 26.2 2.9 6.1e-06 26.2 2.9 4.8 3 2 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC29717.1 - 6.8e-05 23.1 32.0 0.00039 20.7 12.0 3.1 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC29717.1 - 0.058 13.6 21.6 0.58 10.3 7.5 2.9 2 0 0 2 2 2 0 Laminin EGF domain IBV_3C PF03620.13 EGC29718.1 - 0.026 15.0 3.1 0.037 14.5 2.7 1.4 1 1 0 1 1 1 0 IBV 3C protein TMEM208_SND2 PF05620.11 EGC29718.1 - 0.055 13.2 1.9 0.084 12.6 1.9 1.3 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 DUF2207 PF09972.9 EGC29718.1 - 0.11 11.3 6.3 0.13 11.0 6.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) NPCC PF08058.11 EGC29718.1 - 1.7 8.7 4.4 1.3 9.1 1.1 2.0 1 1 1 2 2 2 0 Nuclear pore complex component CLU PF13236.6 EGC29719.1 - 1.9e-57 194.6 0.0 7.5e-57 192.7 0.0 2.1 1 0 0 1 1 1 1 Clustered mitochondria UQ_con PF00179.26 EGC29719.1 - 4.8e-27 94.3 0.0 2.3e-26 92.1 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme eIF3_p135 PF12807.7 EGC29719.1 - 4.1e-10 40.0 0.2 4.1e-10 40.0 0.2 5.3 4 2 2 6 6 6 1 Translation initiation factor eIF3 subunit 135 zf-CCCH PF00642.24 EGC29719.1 - 0.00031 20.6 2.4 0.00058 19.7 1.3 2.0 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGC29719.1 - 0.00068 20.3 8.7 0.00068 20.3 8.7 4.0 5 0 0 5 5 5 1 Torus domain zf-CCCH_4 PF18044.1 EGC29719.1 - 0.0013 18.4 2.6 0.0027 17.5 2.6 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGC29719.1 - 0.002 18.1 5.4 0.0072 16.3 5.4 2.0 1 0 0 1 1 1 1 Zinc finger domain Yip1 PF04893.17 EGC29720.1 - 6.3e-13 48.8 10.3 6.3e-13 48.8 10.3 1.7 1 1 1 2 2 2 2 Yip1 domain YIF1 PF03878.15 EGC29720.1 - 0.064 12.8 9.9 0.14 11.6 9.9 1.7 1 1 0 1 1 1 0 YIF1 Pkinase PF00069.25 EGC29721.1 - 1.5e-36 126.2 5.5 5.6e-18 65.3 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29721.1 - 2.1e-16 60.0 5.0 1.3e-08 34.5 0.3 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase RabGAP-TBC PF00566.18 EGC29723.1 - 2.8e-05 23.9 0.0 2.8e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol_A_exo1 PF01612.20 EGC29725.1 - 3.5e-22 79.0 0.8 6.7e-22 78.0 0.8 1.5 1 0 0 1 1 1 1 3'-5' exonuclease SET PF00856.28 EGC29725.1 - 0.45 10.9 3.2 8.6 6.7 3.7 2.1 1 1 1 2 2 2 0 SET domain cobW PF02492.19 EGC29726.1 - 7e-51 172.3 0.2 1.2e-50 171.6 0.2 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGC29726.1 - 1.3e-17 63.5 0.0 2e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.17 EGC29726.1 - 0.00055 19.8 0.8 0.021 14.6 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.23 EGC29726.1 - 0.0026 17.8 0.0 0.0078 16.3 0.0 1.9 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC29726.1 - 0.0057 16.6 2.5 2 8.3 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase T2SSE PF00437.20 EGC29726.1 - 0.016 14.3 1.1 0.025 13.6 1.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGC29726.1 - 0.02 15.3 0.0 0.045 14.1 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGC29726.1 - 0.022 15.1 0.0 0.078 13.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC29726.1 - 0.033 13.9 0.2 0.085 12.6 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MeaB PF03308.16 EGC29726.1 - 0.039 12.9 0.6 2 7.4 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EGC29726.1 - 0.064 13.0 0.3 0.31 10.7 0.0 2.3 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EGC29726.1 - 0.082 12.9 0.1 0.2 11.7 0.1 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGC29726.1 - 0.14 12.2 1.5 0.36 10.9 0.1 2.5 1 1 0 2 2 2 0 AAA domain MobB PF03205.14 EGC29726.1 - 0.15 11.9 2.8 1.1 9.2 0.1 2.8 3 0 0 3 3 3 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_18 PF13238.6 EGC29726.1 - 0.55 10.8 0.1 0.55 10.8 0.1 2.7 1 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGC29726.1 - 4.2 7.1 9.0 1.3 8.8 0.3 2.9 2 1 1 3 3 3 0 AAA domain RSS_P20 PF11757.8 EGC29726.1 - 8.7 6.9 10.3 0.78 10.2 4.4 2.3 2 0 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain OTU PF02338.19 EGC29728.1 - 9.6e-13 48.7 2.0 4e-12 46.7 0.0 2.4 2 0 0 2 2 2 1 OTU-like cysteine protease SWI-SNF_Ssr4 PF08549.10 EGC29728.1 - 0.00063 18.5 16.0 0.00086 18.1 16.0 1.2 1 0 0 1 1 1 1 Fungal domain of unknown function (DUF1750) Ndc1_Nup PF09531.10 EGC29728.1 - 0.0061 15.3 12.1 0.0064 15.2 12.1 1.1 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Presenilin PF01080.17 EGC29728.1 - 0.09 11.5 19.9 0.12 11.1 19.9 1.2 1 0 0 1 1 1 0 Presenilin NicO PF03824.16 EGC29728.1 - 0.21 10.9 2.0 0.38 10.1 2.0 1.4 1 0 0 1 1 1 0 High-affinity nickel-transport protein PAT1 PF09770.9 EGC29728.1 - 9.5 4.3 34.2 12 4.0 34.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PHD PF00628.29 EGC29729.1 - 2.4e-16 59.3 45.4 8e-07 28.9 6.3 3.8 3 0 0 3 3 3 3 PHD-finger EVE PF01878.18 EGC29729.1 - 1.3e-05 25.3 0.0 4.9e-05 23.4 0.0 2.1 1 0 0 1 1 1 1 EVE domain PHD_2 PF13831.6 EGC29729.1 - 0.038 13.5 21.3 0.04 13.5 3.6 3.0 2 0 0 2 2 2 0 PHD-finger Prok-RING_1 PF14446.6 EGC29729.1 - 4.5 7.3 23.6 0.86 9.6 5.4 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 DUF1990 PF09348.10 EGC29730.1 - 1.1e-48 165.2 0.0 1.4e-48 164.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) DUF4612 PF15389.6 EGC29732.1 - 5.1 8.2 11.7 37 5.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4612) ATP-grasp_2 PF08442.10 EGC29733.1 - 6.1e-77 257.7 0.3 6.1e-77 257.7 0.3 1.8 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.19 EGC29733.1 - 8.9e-27 93.8 1.1 1.9e-26 92.7 1.1 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGC29733.1 - 8.3e-09 35.2 0.0 1.6e-08 34.3 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGC29733.1 - 9.1e-05 22.3 1.8 0.0019 18.0 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain Succ_CoA_lig PF13607.6 EGC29733.1 - 0.02 14.7 0.2 0.1 12.4 0.2 2.0 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RasGEF PF00617.19 EGC29734.1 - 1.4e-51 175.2 3.3 1.7e-51 174.9 1.6 2.1 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC29734.1 - 3.3e-18 65.9 1.0 1.9e-17 63.4 1.0 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif WH1 PF00568.23 EGC29734.1 - 0.0074 16.2 0.1 0.016 15.1 0.1 1.5 1 0 0 1 1 1 1 WH1 domain TIG_plexin PF17960.1 EGC29734.1 - 0.83 9.7 8.0 0.19 11.8 1.2 3.3 4 0 0 4 4 4 0 TIG domain OCD_Mu_crystall PF02423.15 EGC29736.1 - 3.7e-54 183.8 0.1 4.2e-54 183.6 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.20 EGC29736.1 - 4e-08 33.4 0.0 7.3e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGC29736.1 - 0.11 13.0 0.0 0.28 11.7 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Semialdhyde_dh PF01118.24 EGC29736.1 - 0.14 12.6 0.3 0.64 10.5 0.0 2.2 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Coiled PF05710.12 EGC29737.1 - 0.3 11.9 4.6 0.4 11.5 4.6 1.3 1 0 0 1 1 1 0 Coiled coil Dabb PF07876.12 EGC29740.1 - 9.7e-17 61.4 0.0 1.1e-16 61.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain IL2 PF00715.17 EGC29740.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Interleukin 2 2OG-FeII_Oxy_3 PF13640.6 EGC29741.1 - 3.7e-08 34.1 0.0 5.9e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Oxygenase-NA PF09859.9 EGC29741.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.2 1 0 0 1 1 1 0 Oxygenase, catalysing oxidative methylation of damaged DNA Viral_DNA_bi PF02236.17 EGC29742.1 - 0.034 14.3 0.1 8.3 6.7 0.1 2.6 2 0 0 2 2 2 0 Viral DNA-binding protein, all alpha domain SapB_2 PF03489.17 EGC29743.1 - 4e-05 23.6 0.1 4e-05 23.6 0.1 2.2 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC29743.1 - 4.9e-05 23.2 0.8 4.9e-05 23.2 0.8 1.8 2 0 0 2 2 2 1 Saposin-like type B, region 1 SapB_2 PF03489.17 EGC29744.1 - 3e-06 27.2 0.1 3e-06 27.2 0.1 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC29744.1 - 0.00021 21.2 0.8 0.00068 19.6 0.8 1.9 1 1 0 1 1 1 1 Saposin-like type B, region 1 SUIM_assoc PF16619.5 EGC29745.1 - 0.082 13.0 3.3 0.29 11.2 3.3 1.9 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 LapA_dom PF06305.11 EGC29746.1 - 0.79 9.6 0.0 0.79 9.6 0.0 3.1 4 0 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF948 PF06103.11 EGC29746.1 - 5.2 7.4 7.9 80 3.6 7.9 2.7 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF2157 PF09925.9 EGC29747.1 - 0.048 13.5 0.0 0.05 13.4 0.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2157) PARP PF00644.20 EGC29751.1 - 2e-13 50.4 10.4 6.3e-12 45.5 1.2 2.6 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.11 EGC29752.1 - 6.8e-33 114.2 0.0 7.9e-33 114.0 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.20 EGC29753.1 - 1.4e-16 60.6 4.8 1.1e-13 51.3 0.6 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DTW PF03942.15 EGC29753.1 - 0.019 14.6 3.6 0.022 14.4 3.5 1.3 1 1 0 1 1 1 0 DTW domain DUF3990 PF13151.6 EGC29753.1 - 0.056 13.1 1.4 2.3 7.9 0.0 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3990) Ubie_methyltran PF01209.18 EGC29754.1 - 6.9e-08 32.1 0.0 6.9e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGC29754.1 - 4.9e-05 23.9 0.0 6.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29754.1 - 0.00062 20.4 0.0 0.00086 20.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC29754.1 - 0.0015 18.3 0.0 0.0016 18.2 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29754.1 - 0.14 12.9 0.0 0.18 12.6 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain FNIP PF05725.12 EGC29755.1 - 0.002 18.3 0.0 0.0083 16.3 0.0 1.9 2 0 0 2 2 2 1 FNIP Repeat PARP PF00644.20 EGC29757.1 - 1.5e-17 63.8 2.6 1.9e-13 50.5 0.4 2.9 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain CxC6 PF18721.1 EGC29758.1 - 0.091 13.0 7.8 7.9 6.8 0.0 3.4 2 1 1 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Tuberin PF03542.16 EGC29758.1 - 0.26 10.4 0.6 0.34 10.0 0.6 1.2 1 0 0 1 1 1 0 Tuberin zf-C3Hc3H PF13891.6 EGC29758.1 - 0.38 11.2 9.8 5 7.6 0.9 3.5 1 1 2 3 3 3 0 Potential DNA-binding domain Zn-ribbon_8 PF09723.10 EGC29758.1 - 0.74 10.0 0.1 0.74 10.0 0.1 3.2 4 1 0 4 4 4 0 Zinc ribbon domain DDE_Tnp_4 PF13359.6 EGC29759.1 - 7.4e-14 51.7 0.0 2.1e-13 50.2 0.0 1.8 1 0 0 1 1 1 1 DDE superfamily endonuclease Methyltransf_11 PF08241.12 EGC29760.1 - 5.7e-13 49.3 0.0 8.1e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC29760.1 - 1.1e-12 48.0 0.0 1.4e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29760.1 - 1.2e-09 38.7 0.0 2e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC29760.1 - 4.9e-06 26.1 0.2 7.2e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGC29760.1 - 0.00021 21.9 0.0 0.00032 21.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGC29760.1 - 0.013 15.3 0.0 1 9.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGC29760.1 - 0.022 13.3 0.0 0.077 11.5 0.0 1.7 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.6 EGC29760.1 - 0.048 13.7 0.0 0.061 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain EAP30 PF04157.16 EGC29761.1 - 4.4e-44 150.5 0.4 4.4e-44 150.5 0.4 1.8 2 0 0 2 2 2 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.8 EGC29761.1 - 1.3e-13 50.9 0.0 5.3e-13 49.0 0.0 2.1 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 HTH_24 PF13412.6 EGC29761.1 - 0.054 13.1 0.1 0.17 11.5 0.1 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding TFIIA PF03153.13 EGC29761.1 - 0.069 13.1 45.3 0.098 12.6 45.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PP_kinase_N PF13089.6 EGC29761.1 - 0.65 10.4 6.5 1.7 9.0 3.8 2.7 2 0 0 2 2 2 0 Polyphosphate kinase N-terminal domain AIRS_C PF02769.22 EGC29762.1 - 2.1e-26 92.9 0.0 3.2e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.24 EGC29762.1 - 2.2e-07 31.4 0.0 5.9e-07 30.0 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RhoGAP PF00620.27 EGC29763.1 - 8.1e-45 152.4 0.1 1.3e-44 151.7 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_S8 PF00082.22 EGC29764.1 - 5.5e-41 140.8 0.2 1.8e-40 139.1 0.2 1.8 1 1 0 1 1 1 1 Subtilase family Peptidase_C97 PF05903.14 EGC29765.1 - 1.9e-29 102.4 0.2 2.3e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PnpCD_PnpD_N PF18191.1 EGC29767.1 - 0.015 14.9 0.0 0.023 14.3 0.0 1.3 1 0 0 1 1 1 0 Hydroquinone 1,2-dioxygenase large subunit N-terminal DUF3669 PF12417.8 EGC29767.1 - 0.11 12.7 1.3 33 4.8 0.1 3.6 4 0 0 4 4 4 0 Zinc finger protein Reticulon PF02453.17 EGC29768.1 - 0.073 13.0 0.0 0.49 10.3 0.0 2.3 2 0 0 2 2 2 0 Reticulon CRR7 PF12095.8 EGC29768.1 - 0.48 10.9 6.0 13 6.3 1.5 2.8 2 0 0 2 2 2 0 Protein CHLORORESPIRATORY REDUCTION 7 RL PF17797.1 EGC29768.1 - 7.5 6.6 6.7 0.48 10.4 0.7 2.3 2 0 0 2 2 2 0 RL domain RPA_C PF08784.11 EGC29769.1 - 0.042 14.5 6.8 0.084 13.5 6.8 1.5 1 0 0 1 1 1 0 Replication protein A C terminal FA_hydroxylase PF04116.13 EGC29771.1 - 2.1e-28 99.3 16.2 2.1e-28 99.3 16.2 2.0 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Act-Frag_cataly PF09192.10 EGC29772.1 - 1e-74 251.5 9.0 1e-74 251.5 9.0 1.5 2 0 0 2 2 2 1 Actin-fragmin kinase, catalytic SpecificRecomb PF10136.9 EGC29772.1 - 0.037 12.4 0.0 0.051 11.9 0.0 1.2 1 0 0 1 1 1 0 Site-specific recombinase DUF2373 PF10180.9 EGC29773.1 - 1.5e-20 72.8 1.5 3.5e-20 71.6 1.5 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SnoaL_2 PF12680.7 EGC29774.1 - 0.00033 21.3 0.0 0.00037 21.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC29774.1 - 0.079 12.8 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Aldedh PF00171.22 EGC29775.1 - 5.5e-133 443.9 0.0 6.8e-133 443.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGC29775.1 - 0.016 14.6 0.0 0.047 13.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) LuxC PF05893.14 EGC29775.1 - 0.15 11.1 0.2 0.6 9.1 0.2 1.9 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) JmjC PF02373.22 EGC29776.1 - 7.9e-17 61.7 0.2 3.7e-16 59.6 0.0 2.4 2 0 0 2 2 2 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.9 EGC29776.1 - 0.00018 21.7 16.9 0.00018 21.7 16.9 2.4 2 0 0 2 2 2 1 Zinc-finger domain of monoamine-oxidase A repressor R1 PWWP PF00855.17 EGC29776.1 - 0.049 14.1 1.0 0.2 12.1 0.0 2.5 2 1 0 2 2 2 0 PWWP domain Ank_2 PF12796.7 EGC29777.1 - 1.3e-37 128.2 8.4 1.6e-17 63.8 2.6 4.3 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC29777.1 - 1.3e-32 111.7 6.7 1.5e-07 31.9 0.1 6.7 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGC29777.1 - 2.8e-29 100.2 3.4 3.7e-06 27.1 0.1 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EGC29777.1 - 3.9e-26 88.2 11.3 1.3e-05 25.1 0.1 9.1 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EGC29777.1 - 2e-18 66.2 4.3 2.7e-06 27.5 0.1 6.2 3 2 4 7 7 7 5 Ankyrin repeats (many copies) YfmQ PF10787.9 EGC29777.1 - 0.0059 16.4 0.0 0.3 10.9 0.0 2.8 2 1 1 3 3 3 1 Uncharacterised protein from bacillus cereus group Peptidase_M1 PF01433.20 EGC29778.1 - 4.2e-76 255.3 1.2 7e-76 254.6 1.2 1.4 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGC29778.1 - 2e-53 182.0 0.0 3.2e-53 181.3 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGC29778.1 - 2.5e-35 122.4 6.1 1.3e-34 120.1 6.1 2.2 1 1 0 1 1 1 1 Peptidase M1 N-terminal domain HPP PF04982.13 EGC29779.1 - 1.1e-42 145.1 7.5 1.3e-42 144.8 5.8 1.8 2 0 0 2 2 2 1 HPP family Phage_holin_3_3 PF16083.5 EGC29779.1 - 0.0098 16.0 1.7 3.4 7.8 0.2 2.5 2 0 0 2 2 2 2 LydA holin phage, holin superfamily III zf-RING_2 PF13639.6 EGC29780.1 - 3.4e-08 33.7 11.1 5e-08 33.2 11.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC29780.1 - 5.1e-07 29.4 13.2 7.6e-07 28.9 13.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC29780.1 - 3.4e-06 26.8 12.2 4.9e-06 26.3 12.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC29780.1 - 1.9e-05 24.5 7.5 4.1e-05 23.5 7.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC29780.1 - 4.2e-05 23.3 13.1 7.7e-05 22.5 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29780.1 - 0.00049 20.0 13.8 0.0011 18.8 13.7 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGC29780.1 - 0.00059 20.1 12.0 0.002 18.4 12.0 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC29780.1 - 0.00065 19.5 12.9 0.0016 18.3 12.6 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DUF1272 PF06906.11 EGC29780.1 - 0.0092 16.1 8.2 0.015 15.4 8.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Mito_fiss_reg PF05308.11 EGC29780.1 - 0.024 14.7 5.8 0.038 14.1 5.8 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator zf-C3HC4_4 PF15227.6 EGC29780.1 - 0.06 13.5 12.3 0.4 10.9 12.6 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-UDP PF14569.6 EGC29780.1 - 0.15 12.2 5.5 0.37 10.9 5.5 1.6 1 0 0 1 1 1 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.11 EGC29780.1 - 0.22 11.4 8.1 0.35 10.8 8.1 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 EGC29780.1 - 0.52 10.2 10.5 1.4 8.8 10.6 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EGC29780.1 - 0.56 9.9 10.6 0.17 11.5 4.9 2.2 1 1 1 2 2 2 0 P-11 zinc finger zf-TFIIIC PF12660.7 EGC29780.1 - 0.62 10.0 7.1 3.2 7.7 7.1 2.2 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex zf-RING_10 PF16685.5 EGC29780.1 - 3.1 8.0 12.1 8.3 6.6 11.3 2.0 1 1 1 2 2 2 0 zinc RING finger of MSL2 MSA-2c PF12238.8 EGC29780.1 - 7 6.6 10.6 2 8.4 7.1 1.8 2 0 0 2 2 2 0 Merozoite surface antigen 2c Cofilin_ADF PF00241.20 EGC29781.1 - 2.2e-16 59.8 0.0 4.4e-16 58.8 0.0 1.5 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein SH3_1 PF00018.28 EGC29781.1 - 4e-15 55.1 2.2 4.4e-15 55.0 0.2 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGC29781.1 - 4.2e-14 52.1 0.4 1.5e-13 50.4 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.17 EGC29781.1 - 1.8e-11 43.5 0.0 4.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_18 PF13238.6 EGC29782.1 - 7.9e-05 23.2 0.1 7.9e-05 23.2 0.1 3.4 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.12 EGC29782.1 - 0.00016 21.1 0.0 0.00031 20.1 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin DDHD PF02862.17 EGC29782.1 - 0.00064 20.0 6.9 0.022 14.9 4.0 2.3 2 0 0 2 2 2 2 DDHD domain AAA_33 PF13671.6 EGC29782.1 - 0.0021 18.2 0.0 0.0062 16.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC29782.1 - 0.0034 17.6 0.1 0.0061 16.8 0.1 1.4 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC29782.1 - 0.038 13.9 0.0 0.13 12.2 0.0 1.9 1 0 0 1 1 1 0 RsgA GTPase AAA_16 PF13191.6 EGC29782.1 - 0.066 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain APS_kinase PF01583.20 EGC29782.1 - 0.099 12.5 0.1 0.17 11.7 0.1 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_17 PF13207.6 EGC29782.1 - 0.1 13.0 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 AAA domain PRK PF00485.18 EGC29782.1 - 0.18 11.5 3.3 0.7 9.6 0.1 2.7 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_25 PF13481.6 EGC29782.1 - 0.34 10.4 0.7 0.69 9.5 0.7 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGC29782.1 - 0.49 10.9 8.8 0.19 12.2 1.6 3.0 2 1 0 2 2 2 0 ABC transporter Myc_N PF01056.18 EGC29782.1 - 2.2 8.1 13.3 0.58 10.0 9.2 1.9 2 0 0 2 2 2 0 Myc amino-terminal region Peptidase_M49 PF03571.15 EGC29783.1 - 2.3e-224 745.8 0.4 2.8e-224 745.6 0.4 1.1 1 0 0 1 1 1 1 Peptidase family M49 Erf4 PF10256.9 EGC29783.1 - 0.12 12.5 0.3 2 8.5 0.0 2.9 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family Glyoxalase PF00903.25 EGC29785.1 - 2.3e-11 44.0 0.1 1.5e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGC29785.1 - 0.0011 19.2 0.0 0.089 13.1 0.0 2.7 3 0 0 3 3 3 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF1699 PF08004.11 EGC29785.1 - 0.02 14.6 0.0 0.065 12.9 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1699) DUF5582 PF17819.1 EGC29786.1 - 0.00094 19.7 2.6 0.0014 19.1 2.6 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5582) CN_hydrolase PF00795.22 EGC29787.1 - 7.3e-62 209.1 0.0 8.2e-62 208.9 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Laminin_EGF PF00053.24 EGC29788.1 - 0.011 15.9 0.5 0.011 15.9 0.5 2.1 2 0 0 2 2 2 0 Laminin EGF domain Pkinase PF00069.25 EGC29789.1 - 6.2e-74 248.7 0.0 1.1e-73 247.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29789.1 - 2.8e-35 121.9 0.0 4.6e-35 121.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC29789.1 - 2.9e-06 26.8 0.1 6.5e-06 25.7 0.1 1.6 1 1 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGC29789.1 - 0.014 14.2 6.4 0.1 11.3 6.4 2.1 1 1 0 1 1 1 0 Fungal protein kinase POR PF01558.18 EGC29789.1 - 0.061 13.4 0.0 0.19 11.8 0.0 1.8 2 0 0 2 2 2 0 Pyruvate ferredoxin/flavodoxin oxidoreductase T2SSM PF04612.12 EGC29789.1 - 0.53 10.3 7.2 0.88 9.6 7.2 1.3 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M DUF2098 PF09871.9 EGC29789.1 - 0.56 10.6 0.0 0.56 10.6 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) UPF0020 PF01170.18 EGC29790.1 - 6.8e-08 32.4 0.1 0.0055 16.4 0.0 2.4 1 1 1 2 2 2 2 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.18 EGC29790.1 - 0.00017 21.4 0.1 0.00017 21.4 0.1 3.0 2 2 0 2 2 2 1 DNA methylase CWC25 PF12542.8 EGC29792.1 - 2.8e-16 60.3 0.7 2.8e-16 60.3 0.7 5.7 3 1 0 3 3 3 1 Pre-mRNA splicing factor Cir_N PF10197.9 EGC29792.1 - 1.5e-12 47.5 15.1 1.5e-12 47.5 15.1 8.2 6 2 2 8 8 8 1 N-terminal domain of CBF1 interacting co-repressor CIR Gryzun-like PF12742.7 EGC29794.1 - 0.1 12.6 0.7 0.19 11.8 0.2 1.7 1 1 1 2 2 2 0 Gryzun, putative Golgi trafficking Cir_N PF10197.9 EGC29795.1 - 7.4e-11 42.1 6.4 7.4e-11 42.1 6.4 4.0 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR zf-CCHC_6 PF15288.6 EGC29795.1 - 0.051 13.4 0.9 0.051 13.4 0.9 2.1 2 0 0 2 2 2 0 Zinc knuckle Pkinase PF00069.25 EGC29796.1 - 3.2e-09 36.5 2.5 3.2e-09 36.5 2.5 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29796.1 - 8.4e-06 25.2 0.3 1.4e-05 24.5 0.3 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4854 PF16146.5 EGC29796.1 - 0.23 11.8 3.7 0.48 10.8 0.9 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4854) Ldr_toxin PF13940.6 EGC29798.1 - 0.16 12.0 0.3 0.27 11.3 0.3 1.3 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system SelP_N PF04592.14 EGC29798.1 - 4.2 6.7 14.2 5.8 6.2 14.2 1.2 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RhoGAP PF00620.27 EGC29799.1 - 7.5e-27 94.0 0.1 7.5e-27 94.0 0.1 2.7 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.23 EGC29799.1 - 4.5e-11 42.9 0.8 1.9e-10 40.9 0.4 2.4 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain Vfa1 PF08432.10 EGC29799.1 - 0.0029 18.0 18.4 0.0029 18.0 18.4 2.7 2 1 0 2 2 2 1 AAA-ATPase Vps4-associated protein 1 Prefoldin_2 PF01920.20 EGC29800.1 - 6.3e-14 51.8 7.1 7.5e-14 51.6 7.1 1.1 1 0 0 1 1 1 1 Prefoldin subunit YjbR PF04237.13 EGC29800.1 - 0.037 14.6 0.1 0.32 11.6 0.0 2.0 1 1 1 2 2 2 0 YjbR G3P_antiterm PF04309.12 EGC29800.1 - 0.039 13.4 0.1 0.055 12.9 0.1 1.1 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator NPFF PF15085.6 EGC29801.1 - 0.09 13.1 0.2 4.5 7.7 0.1 2.6 3 0 0 3 3 3 0 Neuropeptide FF RRT14 PF17075.5 EGC29802.1 - 0.0032 17.6 0.2 0.0032 17.6 0.2 1.1 1 0 0 1 1 1 1 Regular of rDNA transcription protein 14 EF-hand_7 PF13499.6 EGC29805.1 - 8e-18 64.7 2.2 1.2e-06 28.9 0.0 4.8 3 2 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGC29805.1 - 8.7e-18 62.5 11.9 6.5e-05 22.2 0.1 6.0 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 EGC29805.1 - 5.1e-16 57.2 9.7 0.00042 20.0 0.1 6.6 6 1 1 7 7 6 3 EF-hand domain EF-hand_8 PF13833.6 EGC29805.1 - 6e-14 51.6 2.6 0.0016 18.3 0.2 4.7 5 1 0 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC29805.1 - 1.3e-09 37.1 12.0 0.00048 19.5 0.8 3.7 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.7 EGC29805.1 - 1.3e-06 28.3 3.2 0.32 11.0 0.0 4.2 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGC29805.1 - 0.00018 21.8 0.8 0.013 15.8 0.0 3.5 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGC29805.1 - 0.00026 21.1 0.7 0.0013 18.9 0.0 2.6 2 1 0 2 2 2 1 Dockerin type I domain VCBS PF13517.6 EGC29805.1 - 0.00041 20.9 0.1 0.64 10.6 0.0 3.4 3 0 0 3 3 3 1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EF-hand_9 PF14658.6 EGC29805.1 - 0.016 15.5 0.0 8.9 6.7 0.0 3.3 3 0 0 3 3 3 0 EF-hand domain EFhand_Ca_insen PF08726.10 EGC29805.1 - 0.034 14.2 0.1 0.11 12.7 0.0 1.9 2 0 0 2 2 1 0 Ca2+ insensitive EF hand TcdB_toxin_midN PF12256.8 EGC29805.1 - 0.049 13.0 0.8 9.2 5.6 0.0 3.0 2 1 1 3 3 3 0 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.23 EGC29805.1 - 0.092 12.9 1.5 7.4 6.8 0.1 2.5 2 0 0 2 2 2 0 FG-GAP repeat PIP5K PF01504.18 EGC29806.1 - 3.2e-69 233.2 10.0 5.6e-69 232.4 10.0 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DSPc PF00782.20 EGC29808.1 - 1.9e-28 98.9 0.0 8e-28 96.9 0.0 2.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 EGC29808.1 - 4.8e-21 74.3 36.2 8.1e-11 41.5 3.8 5.7 2 1 4 6 6 6 4 Leucine rich repeat LRR_4 PF12799.7 EGC29808.1 - 9.4e-11 41.8 46.0 2.8e-06 27.6 2.1 6.4 5 2 1 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC29808.1 - 1.7e-05 24.4 10.7 0.0015 18.0 2.1 2.4 1 1 1 2 2 2 2 Leucine-rich repeat Y_phosphatase PF00102.27 EGC29808.1 - 0.0028 17.3 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase LRR_1 PF00560.33 EGC29808.1 - 0.16 12.6 25.5 56 4.9 0.0 10.0 8 1 1 9 9 9 0 Leucine Rich Repeat RR_TM4-6 PF06459.12 EGC29808.1 - 5.9 6.6 11.9 9.9 5.9 11.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Fib_alpha PF08702.10 EGC29809.1 - 0.013 15.6 0.6 0.013 15.6 0.6 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.7 EGC29810.1 - 7.2e-20 71.4 8.7 9.2e-08 32.6 0.5 4.3 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC29810.1 - 2.2e-17 62.8 0.3 4.8e-08 33.1 0.2 4.9 6 0 0 6 6 6 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC29810.1 - 4.8e-17 60.3 1.3 0.0005 20.3 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGC29810.1 - 4.9e-16 58.9 0.8 2.7e-06 27.8 0.0 4.1 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC29810.1 - 1.7e-14 53.5 3.6 1.8e-05 25.0 0.0 5.7 6 0 0 6 6 6 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 EGC29810.1 - 7e-11 41.8 9.1 1.5e-10 40.8 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC29810.1 - 0.00022 21.0 7.4 0.00048 19.9 7.4 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 ChaC PF04752.12 EGC29811.1 - 1.4e-38 132.7 0.0 1.8e-38 132.4 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein PUA PF01472.20 EGC29811.1 - 1e-17 63.8 0.0 1.8e-17 63.1 0.0 1.3 1 0 0 1 1 1 1 PUA domain ISK_Channel PF02060.15 EGC29812.1 - 0.028 14.1 0.0 0.16 11.7 0.0 2.4 2 0 0 2 2 2 0 Slow voltage-gated potassium channel TMEM132D_C PF15706.5 EGC29812.1 - 0.2 11.4 0.9 3.7 7.4 0.3 2.9 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ISK_Channel PF02060.15 EGC29813.1 - 0.14 11.9 0.2 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 Slow voltage-gated potassium channel Acyltransf_C PF16076.5 EGC29814.1 - 5.8e-23 80.8 0.8 1e-22 80.0 0.8 1.4 1 0 0 1 1 1 1 Acyltransferase C-terminus Acyltransferase PF01553.21 EGC29814.1 - 3.2e-15 55.9 0.0 4.8e-15 55.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF4389 PF14333.6 EGC29814.1 - 7.8 6.5 9.3 29 4.7 3.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Sld5 PF05916.11 EGC29815.1 - 1.2e-05 25.8 0.4 2e-05 25.0 0.4 1.4 1 0 0 1 1 1 1 GINS complex protein CD20 PF04103.15 EGC29816.1 - 0.00093 19.3 11.7 0.0011 19.1 11.7 1.2 1 0 0 1 1 1 1 CD20-like family Tetraspanin PF00335.20 EGC29816.1 - 0.013 15.3 15.5 0.014 15.1 15.5 1.2 1 0 0 1 1 1 0 Tetraspanin family FixS PF03597.15 EGC29816.1 - 1.3 8.8 7.5 7.2 6.4 0.5 3.3 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type DUF2070 PF09843.9 EGC29816.1 - 7 4.8 12.4 8.5 4.5 12.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) ketoacyl-synt PF00109.26 EGC29819.1 - 1.6e-60 204.8 0.0 3e-60 203.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC29819.1 - 5.3e-44 150.3 0.0 1.1e-43 149.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC29819.1 - 4.1e-38 131.7 0.0 7.3e-38 130.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC29819.1 - 9.1e-32 109.6 0.0 4.6e-31 107.3 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC29819.1 - 1.1e-27 97.1 0.0 7.9e-26 91.1 0.1 2.6 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC29819.1 - 1.1e-22 80.6 0.0 1.7e-22 80.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC29819.1 - 1.6e-20 73.7 3.1 3e-20 72.8 0.0 3.4 3 0 0 3 3 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC29819.1 - 1e-16 61.3 0.2 4.3e-16 59.4 0.2 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGC29819.1 - 5.9e-11 42.3 0.0 8.4e-07 28.7 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 EGC29819.1 - 4.2e-09 37.6 0.0 1.2e-08 36.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC29819.1 - 8.3e-07 28.9 0.1 2.1e-06 27.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC29819.1 - 6.7e-06 26.4 0.1 2.7e-05 24.4 0.3 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EGC29819.1 - 1.1e-05 25.0 3.9 0.057 12.8 0.0 2.8 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EGC29819.1 - 3.5e-05 24.4 0.0 0.0001 22.9 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC29819.1 - 0.00038 20.3 0.0 0.00099 19.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC29819.1 - 0.0027 17.1 0.0 0.0054 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EGC29819.1 - 0.0093 15.4 1.0 0.031 13.7 0.1 2.2 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_31 PF13847.6 EGC29819.1 - 0.05 13.4 3.1 0.066 13.0 0.0 2.9 3 0 0 3 3 2 0 Methyltransferase domain 23S_rRNA_IVP PF05635.11 EGC29819.1 - 0.068 13.5 3.0 0.095 13.0 0.3 2.7 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein adh_short_C2 PF13561.6 EGC29819.1 - 0.072 12.6 0.3 0.16 11.5 0.3 1.5 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase ketoacyl-synt PF00109.26 EGC29820.1 - 4.6e-62 209.9 0.0 7.9e-62 209.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC29820.1 - 5.1e-43 147.1 0.0 1e-42 146.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC29820.1 - 8.1e-41 140.5 0.0 1.4e-40 139.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC29820.1 - 1.5e-32 112.1 0.0 5.5e-32 110.3 0.0 2.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC29820.1 - 1.8e-26 93.1 0.1 5.9e-24 85.0 0.1 2.8 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC29820.1 - 3.6e-22 79.0 0.0 5.4e-22 78.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC29820.1 - 1.1e-21 77.4 0.0 1.5e-20 73.8 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC29820.1 - 1.2e-17 64.4 0.4 4.2e-17 62.6 0.1 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC29820.1 - 1.3e-10 42.5 0.0 3.6e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC29820.1 - 3.4e-08 33.2 0.1 1e-05 25.1 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EGC29820.1 - 1.1e-06 28.5 0.0 2.8e-06 27.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EGC29820.1 - 2.2e-05 24.0 1.2 0.13 11.7 0.3 2.7 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EGC29820.1 - 2.3e-05 25.0 0.0 0.00011 22.8 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC29820.1 - 6e-05 23.3 0.1 0.00015 22.0 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EGC29820.1 - 0.00066 19.5 0.0 0.0017 18.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC29820.1 - 0.0014 18.1 0.0 0.0031 16.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EGC29820.1 - 0.0044 16.8 2.5 0.05 13.4 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Glycos_transf_4 PF00953.21 EGC29822.1 - 3e-37 128.0 13.4 3e-37 128.0 13.4 1.9 3 0 0 3 3 3 1 Glycosyl transferase family 4 Complex1_LYR PF05347.15 EGC29825.1 - 6.9e-17 61.2 1.3 1e-16 60.7 1.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC29825.1 - 0.0002 22.0 1.4 0.00024 21.8 1.4 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR_1 PF13232.6 EGC29825.1 - 0.00066 20.2 0.1 0.00073 20.1 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Pox_MCEL PF03291.16 EGC29826.1 - 2.5e-72 243.8 11.1 2.5e-72 243.8 11.1 2.1 1 1 0 2 2 2 1 mRNA capping enzyme Methyltransf_25 PF13649.6 EGC29826.1 - 9.6e-07 29.4 0.0 3.8e-06 27.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC29826.1 - 2.6e-06 28.0 0.0 9.2e-06 26.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29826.1 - 5.7e-05 23.8 0.1 5.7e-05 23.8 0.1 3.7 3 1 1 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC29826.1 - 0.00013 21.4 0.5 0.00036 19.9 0.3 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family NNMT_PNMT_TEMT PF01234.17 EGC29826.1 - 0.0051 16.0 0.0 0.0051 16.0 0.0 2.2 2 1 0 2 2 2 1 NNMT/PNMT/TEMT family RRM_1 PF00076.22 EGC29827.1 - 4.2e-66 218.7 7.1 9.3e-19 67.0 0.5 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGC29827.1 - 2.7e-10 40.3 0.2 6e-10 39.2 0.2 1.7 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.11 EGC29827.1 - 2.6e-08 33.8 6.1 0.026 14.6 0.5 4.1 3 1 1 4 4 4 2 RNA binding motif RRM_5 PF13893.6 EGC29827.1 - 3.3e-05 23.5 0.7 2.7 7.6 0.1 3.6 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC29827.1 - 0.00013 21.7 0.2 0.016 15.1 0.0 3.7 4 0 0 4 4 4 1 Occluded RNA-recognition motif Nup35_RRM PF05172.13 EGC29827.1 - 0.00071 19.5 2.6 0.32 11.0 0.2 3.7 4 0 0 4 4 4 1 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.8 EGC29827.1 - 0.006 16.6 0.0 23 5.1 0.0 3.6 3 0 0 3 3 3 0 Limkain b1 SET_assoc PF11767.8 EGC29827.1 - 0.0067 16.1 0.0 3.8 7.2 0.0 3.5 3 0 0 3 3 3 1 Histone lysine methyltransferase SET associated Nup35_RRM_2 PF14605.6 EGC29827.1 - 0.023 14.7 0.8 32 4.6 0.1 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif DWNN PF08783.11 EGC29827.1 - 0.097 13.0 0.6 0.25 11.6 0.6 1.7 1 0 0 1 1 1 0 DWNN domain Peptidase_M48_N PF16491.5 EGC29828.1 - 5.7e-54 182.8 12.5 5.7e-54 182.8 12.5 2.3 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGC29828.1 - 6.4e-38 130.5 0.0 9.9e-38 129.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Pkinase PF00069.25 EGC29829.1 - 2.3e-66 223.9 0.0 5.3e-66 222.7 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29829.1 - 1.9e-46 158.4 0.1 3e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC29829.1 - 5.1e-06 25.5 0.0 5.1e-06 25.5 0.0 3.0 3 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGC29829.1 - 0.0001 21.7 0.1 0.00046 19.6 0.1 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.22 EGC29829.1 - 0.00023 20.8 0.2 0.00044 19.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGC29829.1 - 0.00089 19.2 0.0 0.011 15.7 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC29829.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.21 EGC29830.1 - 5.2e-43 146.5 0.0 6.3e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC29830.1 - 1.3e-09 38.3 0.0 3.8e-09 36.8 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC29830.1 - 8.5e-09 35.1 0.0 1.1e-08 34.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGC29830.1 - 4.8e-08 32.8 0.0 5.5e-08 32.6 0.0 1.2 1 0 0 1 1 1 1 Ras family MMR_HSR1 PF01926.23 EGC29830.1 - 3.3e-07 30.4 0.0 4.9e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGC29830.1 - 2.4e-06 27.0 0.3 0.00098 18.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC29830.1 - 0.0034 16.8 0.0 0.0046 16.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region NAD_binding_2 PF03446.15 EGC29830.1 - 0.011 16.0 0.0 0.014 15.6 0.0 1.1 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase ABC_tran PF00005.27 EGC29830.1 - 0.048 14.2 0.5 0.13 12.8 0.5 1.7 1 1 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.18 EGC29830.1 - 0.049 13.0 0.0 0.11 11.9 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_14 PF13173.6 EGC29830.1 - 0.053 13.5 0.0 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.27 EGC29830.1 - 0.095 12.2 0.1 0.77 9.3 0.1 1.9 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Pkinase PF00069.25 EGC29831.1 - 1.7e-60 204.6 0.0 1.7e-60 204.6 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29831.1 - 1.3e-21 77.1 0.0 1.3e-21 77.1 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Borrelia_P83 PF05262.11 EGC29831.1 - 9.9 4.5 37.2 17 3.7 37.2 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein DUF2089 PF09862.9 EGC29832.1 - 0.25 11.4 2.7 0.39 10.7 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2089) M-factor PF03855.13 EGC29832.1 - 1.4 9.1 5.2 3.3 7.9 0.3 3.0 3 0 0 3 3 3 0 M-factor SET PF00856.28 EGC29833.1 - 2.7e-12 47.4 1.2 4.8e-12 46.6 1.2 1.7 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGC29833.1 - 3e-05 24.0 11.5 3e-05 24.0 11.5 1.8 2 0 0 2 2 2 1 MYND finger Alk_phosphatase PF00245.20 EGC29834.1 - 3.5e-86 289.7 2.6 5.9e-86 289.0 2.6 1.3 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.18 EGC29834.1 - 3.1e-05 23.4 0.4 6.8e-05 22.3 0.1 1.7 2 0 0 2 2 2 1 Metalloenzyme superfamily DTW PF03942.15 EGC29835.1 - 2.7e-39 134.9 2.1 4.7e-39 134.2 2.1 1.3 1 0 0 1 1 1 1 DTW domain PspB PF06667.12 EGC29836.1 - 0.58 10.2 2.6 2.8 8.0 2.6 2.3 1 1 0 1 1 1 0 Phage shock protein B EF-hand_6 PF13405.6 EGC29837.1 - 1.4e-15 55.8 8.1 8.3e-07 28.4 0.3 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGC29837.1 - 2.1e-15 55.0 10.1 8e-07 28.2 0.2 3.8 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGC29837.1 - 1.5e-13 50.9 10.3 8.5e-12 45.4 3.2 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC29837.1 - 9.9e-13 47.7 7.5 2.6e-11 43.2 2.2 2.6 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC29837.1 - 2.1e-06 27.0 11.7 0.0001 21.6 0.6 3.2 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.6 EGC29837.1 - 3.9e-05 23.9 0.5 0.00047 20.4 0.4 2.3 2 1 0 2 2 2 1 EF-hand domain EF-hand_14 PF17959.1 EGC29837.1 - 0.0055 17.0 0.9 1.5 9.2 0.2 2.7 2 1 0 2 2 2 2 EF-hand domain SUB1_ProdP9 PF18213.1 EGC29837.1 - 0.025 14.4 0.2 0.054 13.3 0.2 1.7 1 1 0 1 1 1 0 SUB1 protease Prodomain ProdP9 Caleosin PF05042.13 EGC29837.1 - 0.083 12.8 1.4 6.1 6.7 0.0 3.0 2 1 1 3 3 3 0 Caleosin related protein DUF3349 PF11829.8 EGC29837.1 - 0.084 13.7 0.1 0.86 10.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) HEPN_RiboL-PSP PF18735.1 EGC29837.1 - 0.14 12.1 7.4 0.091 12.7 3.2 2.0 1 1 1 2 2 2 0 RiboL-PSP-HEPN EF-hand_4 PF12763.7 EGC29837.1 - 0.25 11.3 6.6 8.3 6.4 0.4 3.1 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Arm PF00514.23 EGC29838.1 - 0.00056 19.9 1.7 0.44 10.7 0.1 3.3 1 1 0 2 2 2 2 Armadillo/beta-catenin-like repeat Cnd1 PF12717.7 EGC29838.1 - 0.18 11.8 4.1 5.9 6.9 0.1 3.5 2 2 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 MinE PF03776.14 EGC29839.1 - 6.1e-15 55.0 0.7 7.6e-15 54.7 0.7 1.1 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE Membrane_bind PF14564.6 EGC29840.1 - 2.8e-15 56.7 1.5 8.9e-15 55.1 0.5 2.1 2 0 0 2 2 2 1 Membrane binding LIM_bind PF01803.16 EGC29840.1 - 0.051 13.1 0.1 0.083 12.4 0.1 1.3 1 0 0 1 1 1 0 LIM-domain binding protein ZoocinA_TRD PF16775.5 EGC29840.1 - 0.055 13.6 0.0 0.12 12.6 0.0 1.6 1 0 0 1 1 1 0 Target recognition domain of lytic exoenzyme Peptidase_S9 PF00326.21 EGC29841.1 - 2.7e-29 102.2 0.0 5e-29 101.3 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_3 PF07859.13 EGC29841.1 - 1e-06 28.8 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_1 PF00561.20 EGC29841.1 - 1.3e-06 28.2 0.2 0.0012 18.5 0.6 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC29841.1 - 1.9e-06 27.4 0.0 0.0016 17.8 0.0 2.2 1 1 1 2 2 2 2 Serine aminopeptidase, S33 DLH PF01738.18 EGC29841.1 - 9.2e-05 22.1 0.0 0.0026 17.3 0.0 2.3 1 1 0 1 1 1 1 Dienelactone hydrolase family BAAT_C PF08840.11 EGC29841.1 - 0.00081 19.4 0.0 0.0023 17.9 0.0 1.7 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGC29841.1 - 0.0012 19.5 0.0 0.0029 18.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGC29841.1 - 0.002 17.8 0.0 0.0055 16.4 0.0 1.7 1 0 0 1 1 1 1 Serine hydrolase (FSH1) UPF0227 PF05728.12 EGC29841.1 - 0.034 14.1 0.0 0.083 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_2 PF02230.16 EGC29841.1 - 0.091 12.5 0.1 6.4 6.5 0.0 2.6 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase PD40 PF07676.12 EGC29841.1 - 0.11 12.5 0.3 0.34 10.9 0.0 2.0 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat AAA_18 PF13238.6 EGC29842.1 - 1.9e-23 83.4 0.0 3e-23 82.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGC29842.1 - 5.7e-05 23.5 0.0 0.00036 21.0 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EGC29842.1 - 8.1e-05 23.1 0.0 0.00018 21.9 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC29842.1 - 0.0014 19.0 0.0 0.0026 18.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Sigma54_activ_2 PF14532.6 EGC29842.1 - 0.0021 18.2 0.0 0.0043 17.2 0.0 1.6 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.6 EGC29842.1 - 0.0028 17.8 0.1 0.014 15.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC29842.1 - 0.0034 17.6 0.0 0.008 16.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGC29842.1 - 0.0045 16.7 0.0 0.011 15.5 0.0 1.7 2 0 0 2 2 2 1 IstB-like ATP binding protein RuvB_N PF05496.12 EGC29842.1 - 0.0062 16.3 0.0 0.01 15.6 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain NTPase_1 PF03266.15 EGC29842.1 - 0.0067 16.4 0.0 0.024 14.5 0.0 1.8 2 0 0 2 2 2 1 NTPase DUF815 PF05673.13 EGC29842.1 - 0.0073 15.5 0.0 0.026 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ResIII PF04851.15 EGC29842.1 - 0.0075 16.3 0.0 0.054 13.5 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit dNK PF01712.19 EGC29842.1 - 0.0089 15.9 2.1 2.4 8.0 0.0 2.1 1 1 1 2 2 2 2 Deoxynucleoside kinase Sigma54_activat PF00158.26 EGC29842.1 - 0.011 15.4 0.0 0.016 15.0 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_29 PF13555.6 EGC29842.1 - 0.013 15.2 0.1 0.04 13.7 0.0 1.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain SKI PF01202.22 EGC29842.1 - 0.014 15.5 0.0 0.061 13.4 0.0 1.9 1 1 0 1 1 1 0 Shikimate kinase AAA_7 PF12775.7 EGC29842.1 - 0.015 14.8 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region ABC_tran PF00005.27 EGC29842.1 - 0.016 15.7 0.2 0.048 14.2 0.2 1.9 1 1 0 1 1 1 0 ABC transporter MCM PF00493.23 EGC29842.1 - 0.017 14.2 0.0 0.031 13.4 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain RNA_helicase PF00910.22 EGC29842.1 - 0.018 15.4 0.0 0.034 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF2075 PF09848.9 EGC29842.1 - 0.019 14.2 0.0 0.044 13.0 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EGC29842.1 - 0.036 14.1 0.0 0.062 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_24 PF13479.6 EGC29842.1 - 0.038 13.7 0.0 0.12 12.1 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC29842.1 - 0.04 14.2 0.0 0.069 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC29842.1 - 0.044 13.0 0.0 0.089 12.1 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PhoH PF02562.16 EGC29842.1 - 0.062 12.8 0.0 0.45 9.9 0.0 2.1 2 1 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.6 EGC29842.1 - 0.063 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_8 PF12780.7 EGC29842.1 - 0.084 12.2 0.0 0.19 11.0 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_10 PF12846.7 EGC29842.1 - 0.085 11.8 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ATPase PF06745.13 EGC29842.1 - 0.12 11.7 0.3 0.33 10.2 0.0 1.7 2 0 0 2 2 2 0 KaiC FtsK_SpoIIIE PF01580.18 EGC29842.1 - 0.13 11.6 0.1 0.19 11.1 0.1 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_19 PF13245.6 EGC29842.1 - 0.15 12.4 0.0 0.26 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Ploopntkinase3 PF18751.1 EGC29842.1 - 0.16 11.9 0.0 0.2 11.5 0.0 1.2 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Cytidylate_kin PF02224.18 EGC29842.1 - 0.18 11.5 0.0 0.26 11.0 0.0 1.3 1 0 0 1 1 1 0 Cytidylate kinase Mg_chelatase PF01078.21 EGC29842.1 - 0.19 11.1 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI THUMP PF02926.17 EGC29843.1 - 6.6e-10 39.3 0.7 1.8e-09 37.8 0.7 1.8 1 0 0 1 1 1 1 THUMP domain BLOC1_2 PF10046.9 EGC29844.1 - 3.2e-33 113.9 6.2 5.2e-33 113.2 6.2 1.3 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA_13 PF13166.6 EGC29844.1 - 0.0022 16.8 5.8 0.0027 16.4 5.8 1.1 1 0 0 1 1 1 1 AAA domain DUF1722 PF08349.11 EGC29844.1 - 0.0049 17.1 1.4 0.0084 16.4 1.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1722) Nsp1_C PF05064.13 EGC29844.1 - 0.012 15.4 0.9 0.016 15.0 0.3 1.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region Med9 PF07544.13 EGC29844.1 - 0.021 14.9 0.6 0.021 14.9 0.6 2.0 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 ORF6C PF10552.9 EGC29844.1 - 0.031 14.3 1.0 0.031 14.3 1.0 1.9 2 0 0 2 2 2 0 ORF6C domain DUF948 PF06103.11 EGC29844.1 - 0.04 14.2 1.2 0.21 11.9 0.3 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_38N PF01074.22 EGC29844.1 - 0.04 13.3 0.8 0.049 13.0 0.8 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Laminin_II PF06009.12 EGC29844.1 - 0.041 13.9 3.8 1.1 9.2 1.0 2.4 1 1 1 2 2 2 0 Laminin Domain II DUF1465 PF07323.12 EGC29844.1 - 0.048 13.5 0.3 0.094 12.6 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) HsbA PF12296.8 EGC29844.1 - 0.059 13.8 3.6 0.25 11.8 0.9 2.5 2 2 0 2 2 2 0 Hydrophobic surface binding protein A Retrotran_gag_2 PF14223.6 EGC29844.1 - 0.074 12.7 2.2 0.22 11.2 2.2 1.7 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type XhlA PF10779.9 EGC29844.1 - 0.17 12.1 2.7 0.43 10.8 2.7 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF1664 PF07889.12 EGC29844.1 - 0.24 11.5 2.6 0.53 10.3 1.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Seryl_tRNA_N PF02403.22 EGC29844.1 - 0.26 11.5 3.9 1.2 9.4 0.7 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TMF_DNA_bd PF12329.8 EGC29844.1 - 4.3 7.4 8.6 0.097 12.7 1.2 2.0 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Globin PF00042.22 EGC29845.1 - 0.055 14.0 0.3 0.18 12.4 0.1 1.8 2 0 0 2 2 2 0 Globin HSP20 PF00011.21 EGC29846.1 - 1.1e-18 67.2 0.1 4.3e-18 65.3 0.0 2.0 2 0 0 2 2 2 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC29846.1 - 2.8e-10 39.6 0.0 6e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 HSP20-like domain found in ArsA EF-hand_1 PF00036.32 EGC29849.1 - 2.2e-24 83.1 11.9 3.4e-05 23.1 0.4 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC29849.1 - 6.4e-22 77.8 9.6 1.6e-11 44.5 1.8 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC29849.1 - 2e-20 70.9 8.0 2.7e-05 23.8 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC29849.1 - 8e-15 53.6 12.9 0.00092 18.6 0.1 4.6 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGC29849.1 - 3.5e-12 46.0 12.4 1.9e-05 24.4 1.8 4.4 3 2 1 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC29849.1 - 1.2e-07 32.0 1.2 0.017 15.5 0.1 2.4 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGC29849.1 - 0.00013 21.8 6.7 0.54 10.2 0.4 3.7 1 1 3 4 4 4 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGC29849.1 - 0.00032 21.0 1.1 0.063 13.6 0.1 3.1 2 1 1 3 3 3 1 EF-hand domain EF-hand_14 PF17959.1 EGC29849.1 - 0.1 13.0 2.0 2.4 8.6 0.1 2.9 2 1 1 3 3 3 0 EF-hand domain TerB PF05099.13 EGC29849.1 - 0.1 12.5 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Glyco_hydro_85 PF03644.13 EGC29850.1 - 1.8e-85 287.0 11.8 1.3e-82 277.6 10.7 2.6 2 0 0 2 2 2 2 Glycosyl hydrolase family 85 GHL6 PF14871.6 EGC29850.1 - 0.092 12.9 0.3 2.4 8.3 0.2 2.9 2 1 1 3 3 3 0 Hypothetical glycosyl hydrolase 6 FKBP_C PF00254.28 EGC29852.1 - 0.0045 17.3 0.0 0.0047 17.2 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CHIPS PF11434.8 EGC29852.1 - 0.055 13.3 0.0 0.06 13.2 0.0 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS O_anti_polymase PF01901.16 EGC29853.1 - 0.13 11.6 0.5 0.16 11.2 0.5 1.2 1 0 0 1 1 1 0 Putative O-antigen polymerase DUF1451 PF07295.11 EGC29853.1 - 1.6 8.8 12.3 0.1 12.6 5.9 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain PAC3 PF10178.9 EGC29855.1 - 1.5e-21 76.3 0.9 1.7e-21 76.2 0.1 1.5 2 0 0 2 2 2 1 Proteasome assembly chaperone 3 Mito_carr PF00153.27 EGC29856.1 - 7.3e-63 208.5 1.5 1.1e-25 89.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SAM_decarbox PF01536.16 EGC29856.1 - 0.012 14.6 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 Adenosylmethionine decarboxylase Gelsolin PF00626.22 EGC29857.1 - 8.6e-65 214.6 20.3 1.9e-17 62.9 0.1 8.3 8 0 0 8 8 8 7 Gelsolin repeat LRR_8 PF13855.6 EGC29857.1 - 1.8e-24 85.3 43.7 3.4e-06 26.7 9.5 5.5 2 1 2 5 5 5 5 Leucine rich repeat LRR_4 PF12799.7 EGC29857.1 - 7.5e-16 58.0 71.4 1.6e-06 28.3 1.6 7.0 8 0 0 8 8 8 5 Leucine Rich repeats (2 copies) VHP PF02209.19 EGC29857.1 - 6.7e-10 38.9 6.7 6.7e-10 38.9 6.7 3.0 2 0 0 2 2 2 1 Villin headpiece domain LRR_6 PF13516.6 EGC29857.1 - 0.0077 16.2 30.1 0.98 9.6 0.0 7.2 7 0 0 7 7 7 4 Leucine Rich repeat LRR_1 PF00560.33 EGC29857.1 - 0.15 12.7 39.2 9.3 7.3 0.3 10.0 9 1 0 9 9 9 0 Leucine Rich Repeat Toxin_YhaV PF11663.8 EGC29859.1 - 0.017 15.2 0.0 0.02 14.9 0.0 1.2 1 0 0 1 1 1 0 Toxin with endonuclease activity, of toxin-antitoxin system Pacs-1 PF10254.9 EGC29860.1 - 6e-26 91.4 0.3 6e-26 91.4 0.3 4.4 3 2 1 4 4 4 2 PACS-1 cytosolic sorting protein LigB PF02900.18 EGC29860.1 - 0.12 11.4 0.1 0.22 10.6 0.1 1.3 1 0 0 1 1 1 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase adh_short PF00106.25 EGC29861.1 - 9.1e-57 191.7 0.3 1.3e-56 191.2 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC29861.1 - 3.3e-37 128.3 0.0 3.9e-37 128.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC29861.1 - 2.1e-15 57.1 0.1 3.1e-15 56.5 0.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC29861.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.5 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family MID_MedPIWI PF18296.1 EGC29862.1 - 4.8e-41 141.2 21.9 4.8e-41 141.2 21.9 7.9 6 2 0 6 6 6 1 MID domain of medPIWI Med13_C PF06333.12 EGC29862.1 - 2.2e-23 83.1 0.1 2.2e-23 83.1 0.1 8.5 6 2 0 6 6 6 1 Mediator complex subunit 13 C-terminal domain Mucin PF01456.17 EGC29863.1 - 0.19 11.8 22.6 0.29 11.1 22.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EGC29863.1 - 8.2 4.3 28.2 11 3.8 28.2 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ABC_tran_CTD PF16326.5 EGC29865.1 - 0.13 12.6 0.3 0.42 10.9 0.3 1.9 1 0 0 1 1 1 0 ABC transporter C-terminal domain DUF1161 PF06649.12 EGC29866.1 - 0.14 12.4 0.4 0.46 10.7 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1161) DUF3439 PF11921.8 EGC29867.1 - 2.4 8.1 9.8 7.4 6.6 9.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Gelsolin PF00626.22 EGC29868.1 - 3.7e-19 68.4 15.7 1.9e-06 27.7 0.0 6.0 6 0 0 6 6 6 5 Gelsolin repeat Connexin PF00029.19 EGC29868.1 - 9.9 5.8 10.6 4 7.1 7.6 1.9 1 1 0 1 1 1 0 Connexin VWA_2 PF13519.6 EGC29869.1 - 5.2e-08 33.5 1.9 1.2e-06 29.1 0.1 3.0 3 0 0 3 3 3 1 von Willebrand factor type A domain MMR_HSR1 PF01926.23 EGC29869.1 - 1.9e-07 31.2 2.5 1.4e-05 25.2 0.3 3.5 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC29869.1 - 0.021 14.9 5.5 1.5 8.9 0.1 3.1 2 1 0 3 3 3 0 Dynamin family MAP PF03642.13 EGC29869.1 - 0.027 14.7 2.4 0.13 12.6 1.1 2.9 2 0 0 2 2 2 0 MAP domain AAA_16 PF13191.6 EGC29869.1 - 0.052 13.9 0.0 0.096 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain ILEI PF15711.5 EGC29869.1 - 0.12 12.8 2.3 1.7 9.2 0.0 3.2 3 0 0 3 3 3 0 Interleukin-like EMT inducer VWA_2 PF13519.6 EGC29870.1 - 1e-08 35.8 0.7 7e-08 33.1 0.1 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain ILEI PF15711.5 EGC29870.1 - 0.065 13.7 0.8 0.66 10.5 0.0 2.5 2 0 0 2 2 2 0 Interleukin-like EMT inducer MMR_HSR1 PF01926.23 EGC29871.1 - 6.4e-07 29.4 0.1 2.4e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC29871.1 - 0.028 14.5 1.9 8 6.5 0.0 3.3 3 0 0 3 3 3 0 Dynamin family DDE_Tnp_4 PF13359.6 EGC29872.1 - 1.5e-07 31.2 0.2 2.4e-06 27.3 0.1 2.1 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF3212 PF11486.8 EGC29872.1 - 0.006 16.6 0.0 0.015 15.3 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3212) DUF963 PF06131.11 EGC29872.1 - 0.018 14.5 10.6 0.018 14.5 10.6 3.8 1 1 2 3 3 3 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF2573 PF10835.8 EGC29873.1 - 0.00062 20.1 0.1 0.0011 19.3 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2573) LIP PF03583.14 EGC29873.1 - 0.039 13.3 0.3 0.041 13.2 0.3 1.1 1 0 0 1 1 1 0 Secretory lipase Complex1_LYR PF05347.15 EGC29873.1 - 0.044 13.8 1.4 0.14 12.3 0.4 2.1 2 0 0 2 2 2 0 Complex 1 protein (LYR family) RabGAP-TBC PF00566.18 EGC29874.1 - 1.7e-19 70.4 1.6 2.3e-19 69.9 1.6 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EGF_CA PF07645.15 EGC29875.1 - 7.9e-11 42.0 25.4 7.3e-08 32.5 10.3 7.7 5 2 2 7 7 7 2 Calcium-binding EGF domain EGF_2 PF07974.13 EGC29875.1 - 9.5e-06 25.9 14.7 9.5e-06 25.9 14.7 7.2 5 1 1 6 6 6 2 EGF-like domain TIG PF01833.24 EGC29875.1 - 1.8e-05 24.7 3.8 2.9e-05 24.0 1.1 2.8 2 0 0 2 2 2 1 IPT/TIG domain EGF_3 PF12947.7 EGC29875.1 - 6.7e-05 23.0 17.7 0.00021 21.4 6.2 7.3 4 1 1 6 6 6 3 EGF domain cEGF PF12662.7 EGC29875.1 - 0.00042 20.2 43.4 0.00056 19.8 2.5 6.4 6 0 0 6 6 6 3 Complement Clr-like EGF-like EB PF01683.18 EGC29875.1 - 0.0031 17.8 79.0 0.021 15.1 2.3 7.3 3 1 4 7 7 7 4 EB module EGF PF00008.27 EGC29875.1 - 0.0049 17.2 75.5 0.064 13.6 9.2 7.1 6 0 0 6 6 6 5 EGF-like domain hEGF PF12661.7 EGC29875.1 - 0.44 11.3 70.0 0.087 13.5 3.7 8.3 7 1 0 7 7 7 0 Human growth factor-like EGF Rpr2 PF04032.16 EGC29876.1 - 2.4e-18 66.2 3.1 2.4e-18 66.2 3.1 2.5 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DDE_Tnp_4 PF13359.6 EGC29876.1 - 6.9e-16 58.3 2.0 1.1e-15 57.7 0.1 2.3 2 1 0 2 2 2 1 DDE superfamily endonuclease BSP_II PF05432.11 EGC29876.1 - 0.0042 16.8 9.6 0.0042 16.8 9.6 2.9 3 0 0 3 3 3 1 Bone sialoprotein II (BSP-II) FAM176 PF14851.6 EGC29876.1 - 0.0097 15.6 5.3 0.0097 15.6 5.3 3.5 4 0 0 4 4 4 1 FAM176 family CENP-O PF09496.10 EGC29876.1 - 0.012 15.5 0.2 0.012 15.5 0.2 1.8 2 0 0 2 2 2 0 Cenp-O kinetochore centromere component HTH_Tnp_4 PF13613.6 EGC29876.1 - 0.12 12.1 0.1 0.22 11.3 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF4746 PF15928.5 EGC29876.1 - 0.25 10.7 11.4 0.18 11.2 8.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) Gti1_Pac2 PF09729.9 EGC29876.1 - 2.2 8.3 8.1 3.7 7.6 0.7 2.4 2 0 0 2 2 2 0 Gti1/Pac2 family Auto_anti-p27 PF06677.12 EGC29876.1 - 2.6 8.3 6.0 6 7.1 0.3 3.3 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Neur_chan_memb PF02932.16 EGC29876.1 - 4.1 7.4 6.3 6.4 6.8 0.4 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region eIF-3c_N PF05470.12 EGC29876.1 - 4.5 5.5 12.4 0.72 8.1 7.5 1.9 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Herpes_UL69 PF05459.12 EGC29877.1 - 0.04 13.3 0.1 0.04 13.3 0.1 2.3 3 0 0 3 3 3 0 Herpesvirus transcriptional regulator family Chromo PF00385.24 EGC29879.1 - 8.8e-07 28.7 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-CCHC PF00098.23 EGC29880.1 - 0.00081 19.4 1.0 0.0013 18.7 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EGC29880.1 - 0.0014 18.4 1.1 0.0014 18.4 1.1 1.8 2 0 0 2 2 2 1 C2H2 zinc-finger ATG16 PF08614.11 EGC29880.1 - 0.0064 16.7 9.6 0.02 15.1 9.6 1.9 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 EGC29880.1 - 0.013 14.8 9.1 0.013 14.8 9.1 3.4 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Cnn_1N PF07989.11 EGC29880.1 - 0.014 15.5 17.2 0.1 12.8 0.6 4.3 1 1 3 4 4 4 0 Centrosomin N-terminal motif 1 Phi-29_GP4 PF05464.11 EGC29880.1 - 0.13 12.5 2.9 0.16 12.2 0.1 2.5 2 1 1 3 3 3 0 Phi-29-like late genes activator (early protein GP4) RMP PF14996.6 EGC29880.1 - 1.7 8.9 11.0 4.5 7.5 0.1 3.2 2 1 2 4 4 4 0 Retinal Maintenance Atg14 PF10186.9 EGC29880.1 - 2.6 7.0 12.3 5.2 6.1 12.3 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Mannosyl_trans PF05007.13 EGC29881.1 - 8.9e-81 271.6 30.4 8.9e-81 271.6 30.4 1.5 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.13 EGC29881.1 - 1.4e-13 50.7 17.8 1.4e-13 50.7 17.8 2.1 1 1 1 2 2 2 1 GPI transamidase subunit PIG-U GT87 PF09594.10 EGC29881.1 - 0.0019 18.0 15.6 0.0019 18.0 15.6 3.0 2 1 0 2 2 2 1 Glycosyltransferase family 87 SAPS PF04499.15 EGC29882.1 - 1.7e-07 30.4 1.0 5e-06 25.6 0.2 6.8 4 1 1 5 5 5 3 SIT4 phosphatase-associated protein DUF3439 PF11921.8 EGC29882.1 - 0.16 11.9 23.2 0.48 10.4 23.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC29882.1 - 0.67 9.9 31.8 0.77 9.7 29.1 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HEAT PF02985.22 EGC29883.1 - 1.7e-06 27.8 2.6 0.23 11.8 0.1 5.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.6 EGC29883.1 - 0.014 15.9 0.1 92 3.7 0.0 5.5 7 0 0 7 7 7 0 HEAT-like repeat HEAT_2 PF13646.6 EGC29883.1 - 0.029 14.8 0.0 27 5.2 0.0 4.4 4 0 0 4 4 4 0 HEAT repeats Arm PF00514.23 EGC29883.1 - 0.21 11.7 1.2 17 5.7 0.0 4.4 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Importin_rep_6 PF18829.1 EGC29883.1 - 0.25 11.5 3.0 0.75 10.0 2.0 2.4 2 0 0 2 2 2 0 Importin repeat 6 Mito_carr PF00153.27 EGC29884.1 - 1.9e-57 191.2 7.9 2.4e-18 65.8 0.6 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Acyl_transf_1 PF00698.21 EGC29885.1 - 2.1e-43 149.0 0.0 4.1e-43 148.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC29885.1 - 1.1e-32 112.5 0.0 2.5e-32 111.4 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGC29885.1 - 1.1e-25 90.6 0.2 2e-25 89.9 0.2 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain KR PF08659.10 EGC29885.1 - 6.4e-24 84.8 0.0 1.5e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC29885.1 - 7.2e-23 81.2 2.6 2.1e-21 76.5 0.0 4.0 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC29885.1 - 6e-20 71.7 0.0 9.2e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC29885.1 - 1.9e-15 57.3 0.1 7.1e-15 55.4 0.1 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC29885.1 - 5.6e-08 33.9 0.0 2.1e-07 32.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGC29885.1 - 1.3e-05 25.1 0.0 4.5e-05 23.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC29885.1 - 1.9e-05 25.2 0.0 6.2e-05 23.6 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC29885.1 - 3e-05 24.3 0.2 7.4e-05 23.0 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGC29885.1 - 3.4e-05 23.7 0.1 8e-05 22.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC29885.1 - 0.00016 21.1 0.1 0.0003 20.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EGC29885.1 - 0.0041 16.9 1.0 0.42 10.4 0.0 3.6 2 0 0 2 2 2 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EGC29885.1 - 0.03 13.7 0.1 0.082 12.3 0.1 1.7 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Arf PF00025.21 EGC29886.1 - 2.4e-78 261.6 0.1 2.9e-78 261.3 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC29886.1 - 4.1e-15 56.1 0.0 5.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC29886.1 - 5.3e-15 55.3 0.0 6.3e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC29886.1 - 3.3e-14 52.8 2.2 2e-10 40.4 0.7 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGC29886.1 - 9.4e-13 48.1 0.0 1.1e-12 47.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGC29886.1 - 3.7e-12 46.1 0.0 4.5e-12 45.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC29886.1 - 7.3e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGC29886.1 - 0.0093 15.3 0.7 0.029 13.7 0.7 1.8 1 1 0 1 1 1 1 6-phosphofructo-2-kinase UPF1_Zn_bind PF09416.10 EGC29887.1 - 1.4e-62 210.2 7.6 1.4e-62 210.2 7.6 2.6 3 0 0 3 3 3 1 RNA helicase (UPF2 interacting domain) DUF5599 PF18141.1 EGC29887.1 - 6.7e-16 58.3 0.0 1.8e-15 56.9 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF5599) Nop14 PF04147.12 EGC29887.1 - 0.89 7.7 41.9 0.023 12.9 24.7 2.2 2 0 0 2 2 2 0 Nop14-like family UAA PF08449.11 EGC29888.1 - 2.3e-58 197.8 12.7 2.7e-58 197.6 12.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGC29888.1 - 3.5e-10 40.2 19.3 1.3e-06 28.6 10.3 2.1 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGC29888.1 - 0.14 11.4 12.7 0.63 9.3 12.7 1.9 1 1 0 1 1 1 0 Triose-phosphate Transporter family Internalin_N PF12354.8 EGC29888.1 - 1.1 9.3 3.5 1.8 8.7 0.1 3.0 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal DUF3430 PF11912.8 EGC29889.1 - 9e-20 71.6 35.0 1e-19 71.5 35.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Pkinase_Tyr PF07714.17 EGC29890.1 - 9.7e-59 198.7 0.0 1.5e-58 198.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC29890.1 - 1.9e-56 191.3 0.0 3.4e-56 190.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGC29890.1 - 2.4e-09 37.2 0.1 1.3e-08 34.8 0.0 2.2 2 0 0 2 2 2 1 SH2 domain Cbl_N3 PF02762.14 EGC29890.1 - 0.00057 19.7 0.0 0.0015 18.3 0.0 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain APH PF01636.23 EGC29890.1 - 0.0075 16.2 0.0 0.05 13.5 0.0 2.2 2 0 0 2 2 2 1 Phosphotransferase enzyme family Lzipper-MIP1 PF14389.6 EGC29890.1 - 1.3 9.4 8.4 3 8.2 8.4 1.7 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 XRN_N PF03159.18 EGC29891.1 - 1.3e-29 103.4 0.1 1.3e-29 103.4 0.1 2.2 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Complex1_51K PF01512.17 EGC29892.1 - 4.9e-48 162.9 0.0 9.8e-48 161.9 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.9 EGC29892.1 - 2.3e-29 101.3 0.0 4.4e-29 100.4 0.0 1.5 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.9 EGC29892.1 - 2.6e-08 33.6 0.0 6.9e-08 32.2 0.0 1.8 2 0 0 2 2 2 1 SLBB domain Myb_DNA-binding PF00249.31 EGC29893.1 - 7.2e-32 109.3 1.9 4.5e-15 55.6 0.3 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC29893.1 - 3.3e-24 84.9 0.3 3.6e-15 56.0 0.1 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain CBM49 PF09478.10 EGC29895.1 - 4.8e-15 55.6 0.2 6.8e-15 55.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Dala_Dala_lig_N PF01820.21 EGC29897.1 - 0.3 11.6 2.3 0.3 11.6 0.2 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FNIP PF05725.12 EGC29898.1 - 1.7e-182 591.4 89.2 1.4e-17 63.6 0.5 15.2 12 3 1 14 14 14 14 FNIP Repeat NNMT_PNMT_TEMT PF01234.17 EGC29898.1 - 0.15 11.2 0.7 3.4 6.8 0.0 2.9 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family CBM49 PF09478.10 EGC29899.1 - 4.8e-15 55.6 0.2 6.8e-15 55.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CH PF00307.31 EGC29900.1 - 1.8e-39 134.3 12.4 6.9e-11 42.3 0.2 5.7 5 0 0 5 5 5 4 Calponin homology (CH) domain PH PF00169.29 EGC29900.1 - 1.1e-15 58.0 1.6 7.8e-15 55.3 0.1 2.9 2 0 0 2 2 2 1 PH domain FERM_f0 PF16511.5 EGC29900.1 - 2.2e-12 47.1 4.4 1.7e-10 41.0 0.0 3.4 3 0 0 3 3 3 2 N-terminal or F0 domain of Talin-head FERM PH_11 PF15413.6 EGC29900.1 - 0.00024 21.5 0.1 0.00024 21.5 0.1 4.4 4 1 0 4 4 4 1 Pleckstrin homology domain CH_2 PF06294.11 EGC29900.1 - 0.00061 19.9 2.3 1.2 9.3 0.0 4.5 5 0 0 5 5 5 2 CH-like domain in sperm protein Stm1_N PF09598.10 EGC29900.1 - 7.1 7.6 6.3 35 5.3 6.3 2.2 1 0 0 1 1 1 0 Stm1 Glyco_transf_5 PF08323.11 EGC29901.1 - 9.9e-37 126.9 0.0 2.2e-36 125.8 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.20 EGC29901.1 - 4.3e-12 45.9 0.0 1.6e-11 44.0 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC29901.1 - 8.7e-08 32.7 0.0 2.6e-07 31.2 0.0 1.8 1 1 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC29901.1 - 0.039 13.9 0.1 0.13 12.2 0.1 1.9 1 1 0 1 1 1 0 Glycosyltransferase Family 4 Alpha-amylase PF00128.24 EGC29901.1 - 3.3 7.2 6.6 4.8 6.6 0.1 3.2 2 1 1 3 3 3 0 Alpha amylase, catalytic domain Spike_rec_bind PF09408.10 EGC29902.1 - 0.00021 21.1 1.7 0.00063 19.5 0.2 2.5 1 1 0 2 2 2 1 Spike receptor binding domain Yqai PF09466.10 EGC29902.1 - 0.083 13.2 1.0 1.5 9.1 0.1 3.0 3 0 0 3 3 3 0 Hypothetical protein Yqai DUF3430 PF11912.8 EGC29903.1 - 2.2e-12 47.5 25.3 2.7e-12 47.2 25.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC29903.1 - 0.69 10.2 8.4 2 8.7 0.3 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) DUF515 PF04415.12 EGC29903.1 - 2.5 6.4 4.6 4.1 5.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF515) FGase PF05013.12 EGC29904.1 - 0.0039 17.4 0.7 0.9 9.7 1.2 3.1 2 1 0 2 2 2 1 N-formylglutamate amidohydrolase PRMT5 PF05185.16 EGC29904.1 - 0.048 13.5 0.0 0.079 12.8 0.0 1.2 1 0 0 1 1 1 0 PRMT5 arginine-N-methyltransferase TT1725 PF18324.1 EGC29904.1 - 0.12 12.5 0.0 0.26 11.4 0.0 1.6 1 0 0 1 1 1 0 Hypothetical protein TT1725 Cyto_heme_lyase PF01265.17 EGC29906.1 - 1.2e-57 195.7 9.4 9e-57 192.9 9.4 1.9 1 1 0 1 1 1 1 Cytochrome c/c1 heme lyase Polysacc_deac_3 PF15421.6 EGC29906.1 - 0.011 14.3 0.1 0.015 13.9 0.1 1.1 1 0 0 1 1 1 0 Putative polysaccharide deacetylase DUF5040 PF16443.5 EGC29906.1 - 0.057 12.8 0.1 0.069 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5040) SNF5 PF04855.12 EGC29906.1 - 0.063 13.1 0.5 0.086 12.6 0.5 1.2 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 D123 PF07065.14 EGC29907.1 - 8.9e-101 337.1 14.5 1.1e-100 336.7 14.5 1.1 1 0 0 1 1 1 1 D123 Sigma70_ner PF04546.13 EGC29907.1 - 0.021 14.7 2.6 0.021 14.7 2.6 1.6 2 0 0 2 2 2 0 Sigma-70, non-essential region NOA36 PF06524.12 EGC29907.1 - 0.059 12.7 6.3 0.091 12.1 6.3 1.2 1 0 0 1 1 1 0 NOA36 protein R2K_2 PF18299.1 EGC29907.1 - 0.069 13.0 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 2 R2K_3 PF14243.6 EGC29907.1 - 0.16 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 ATP-grasp domain, R2K clade family 3 Rrp44_CSD1 PF17216.3 EGC29907.1 - 0.44 10.3 3.8 0.9 9.2 3.8 1.5 1 0 0 1 1 1 0 Rrp44-like cold shock domain FAM176 PF14851.6 EGC29907.1 - 0.53 9.9 6.3 0.28 10.8 3.9 1.7 2 0 0 2 2 2 0 FAM176 family Sporozoite_P67 PF05642.11 EGC29907.1 - 0.62 8.1 5.5 1 7.3 5.5 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PBP1_TM PF14812.6 EGC29907.1 - 0.88 10.0 8.7 2.8 8.4 8.7 1.9 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CENP-B_dimeris PF09026.10 EGC29907.1 - 2.3 8.7 11.5 7 7.1 11.5 1.8 1 0 0 1 1 1 0 Centromere protein B dimerisation domain RasGAP PF00616.19 EGC29908.1 - 1.3e-50 172.0 8.7 1.3e-50 172.0 8.7 3.6 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.31 EGC29908.1 - 2.9e-32 111.1 2.7 1.2e-17 64.0 0.0 3.7 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC29908.1 - 0.0015 18.3 0.2 0.0091 15.8 0.1 2.3 2 0 0 2 2 2 1 CAMSAP CH domain Eco57I PF07669.11 EGC29908.1 - 0.26 11.8 2.5 0.49 10.9 0.1 2.8 3 0 0 3 3 3 0 Eco57I restriction-modification methylase Alpha_L_fucos PF01120.17 EGC29909.1 - 2.7e-103 346.1 14.5 5.8e-103 345.0 14.5 1.5 1 1 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 EGC29909.1 - 2e-12 47.5 0.0 4.2e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain Rib_5-P_isom_A PF06026.14 EGC29910.1 - 9.2e-61 204.4 0.0 1.2e-60 204.1 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.13 EGC29910.1 - 0.0028 16.8 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.22 EGC29910.1 - 0.0066 16.4 0.0 0.013 15.5 0.0 1.4 1 0 0 1 1 1 1 DeoR C terminal sensor domain Amidase PF01425.21 EGC29911.1 - 5.1e-92 309.2 0.0 1.4e-91 307.7 0.0 1.6 1 1 0 1 1 1 1 Amidase Ssu72 PF04722.13 EGC29912.1 - 1.2e-73 246.8 0.2 1.3e-73 246.6 0.2 1.0 1 0 0 1 1 1 1 Ssu72-like protein Neur_chan_memb PF02932.16 EGC29913.1 - 0.00067 19.8 2.1 0.0015 18.6 2.1 1.5 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region zf-RING_2 PF13639.6 EGC29915.1 - 3e-10 40.3 11.2 5e-10 39.6 11.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC29915.1 - 5e-08 32.7 7.9 7.8e-08 32.1 7.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29915.1 - 1.6e-07 31.1 13.1 3.2e-07 30.1 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29915.1 - 1.8e-07 30.9 11.4 3.1e-07 30.1 11.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29915.1 - 3.1e-07 30.6 9.2 1.1e-06 28.8 9.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC29915.1 - 3.4e-05 23.6 6.9 6.8e-05 22.6 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC29915.1 - 0.00015 21.7 9.8 0.00027 20.8 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC29915.1 - 0.0076 16.3 5.8 0.02 14.9 5.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC29915.1 - 0.013 15.7 8.0 0.028 14.6 7.5 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC29915.1 - 0.022 14.6 9.6 0.042 13.6 9.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC29915.1 - 0.036 14.1 3.4 0.093 12.8 3.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC29915.1 - 0.072 13.2 4.6 0.16 12.1 4.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 EGC29915.1 - 0.11 12.7 9.5 0.33 11.2 9.5 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 EGC29915.1 - 0.16 11.7 6.1 0.35 10.7 6.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGC29915.1 - 1.1 9.4 7.0 2 8.6 7.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC29915.1 - 2 8.1 7.9 3.2 7.4 7.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Sad1_UNC PF07738.13 EGC29917.1 - 3.4e-32 111.2 1.2 3.4e-32 111.2 1.2 2.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Dickkopf_N PF04706.12 EGC29918.1 - 1e-05 25.9 14.3 1e-05 25.9 14.3 5.5 3 2 2 5 5 5 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGC29918.1 - 0.018 15.3 5.3 0.018 15.3 5.3 7.9 1 1 6 7 7 7 0 EB module 7TM_GPCR_Str PF10326.9 EGC29919.1 - 0.0042 16.5 9.2 0.0042 16.5 9.2 2.4 1 1 2 3 3 3 1 Serpentine type 7TM GPCR chemoreceptor Str Pox_A14 PF05767.12 EGC29919.1 - 0.0098 16.0 4.0 0.0098 16.0 4.0 2.6 3 0 0 3 3 3 1 Poxvirus virion envelope protein A14 HisKA_7TM PF16927.5 EGC29919.1 - 0.012 15.7 3.1 0.012 15.7 3.1 2.6 3 0 0 3 3 3 0 N-terminal 7TM region of histidine kinase Claudin_2 PF13903.6 EGC29919.1 - 0.014 15.2 0.5 0.014 15.2 0.5 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.23 EGC29919.1 - 0.045 13.8 3.0 0.16 12.0 1.1 2.3 2 1 0 2 2 2 0 Membrane-associating domain UPF0114 PF03350.16 EGC29919.1 - 0.091 13.0 6.5 0.052 13.7 3.4 2.2 2 0 0 2 2 2 0 Uncharacterized protein family, UPF0114 PMP22_Claudin PF00822.20 EGC29919.1 - 0.13 12.2 4.2 0.075 12.9 1.2 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family Voltage_CLC PF00654.20 EGC29919.1 - 0.25 10.5 4.2 1.3 8.2 4.4 1.9 1 1 1 2 2 2 0 Voltage gated chloride channel Fig1 PF12351.8 EGC29919.1 - 0.51 10.2 4.1 0.17 11.8 0.8 1.9 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DHHC PF01529.20 EGC29919.1 - 4.5 7.4 14.6 0.38 10.9 4.8 3.1 3 0 0 3 3 3 0 DHHC palmitoyltransferase SUR7 PF06687.12 EGC29919.1 - 6.8 6.3 11.6 3 7.4 8.2 2.1 2 1 0 2 2 2 0 SUR7/PalI family p450 PF00067.22 EGC29920.1 - 4.8e-73 246.5 0.1 5.9e-73 246.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_35 PF14516.6 EGC29921.1 - 0.0025 16.7 2.1 0.0055 15.6 2.0 1.5 1 1 0 1 1 1 1 AAA-like domain Pro_isomerase PF00160.21 EGC29923.1 - 5.7e-48 163.2 0.1 6.6e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAA_hydrolase PF01557.18 EGC29924.1 - 1.3e-58 198.3 0.0 1.8e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.11 EGC29924.1 - 6.2e-31 106.8 0.0 1.4e-30 105.6 0.0 1.6 1 0 0 1 1 1 1 Fumarylacetoacetase N-terminal SmaI PF17411.2 EGC29924.1 - 0.12 11.5 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease DUF4604 PF15377.6 EGC29925.1 - 0.57 10.6 31.1 0.96 9.8 31.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) MRP-S34 PF16053.5 EGC29926.1 - 2e-12 46.9 0.1 2.3e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial 28S ribosomal protein S34 RhoGEF PF00621.20 EGC29927.1 - 1.5e-49 168.7 6.1 1.5e-49 168.7 6.1 2.3 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 EGC29927.1 - 8e-14 51.7 4.6 1.2e-13 51.2 0.5 3.2 3 0 0 3 3 3 1 Calponin homology (CH) domain VHP PF02209.19 EGC29927.1 - 1.1e-12 47.8 5.2 2.6e-12 46.6 5.2 1.7 1 0 0 1 1 1 1 Villin headpiece domain CDC24 PF06395.11 EGC29927.1 - 1.9e-05 24.8 0.1 6.5e-05 23.1 0.1 2.0 1 0 0 1 1 1 1 CDC24 Calponin CENP-H PF05837.12 EGC29928.1 - 4.2 7.8 12.6 0.64 10.5 5.4 2.4 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Kelch_1 PF01344.25 EGC29929.1 - 1.8e-38 129.9 2.0 2.6e-08 33.3 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGC29929.1 - 1.6e-36 123.4 8.3 2.3e-10 40.4 0.0 6.7 4 1 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC29929.1 - 2.2e-35 120.4 10.2 4.5e-08 33.0 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC29929.1 - 2.2e-34 117.1 9.0 2e-07 31.1 0.1 7.0 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC29929.1 - 2.6e-30 103.9 1.1 0.00014 21.8 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC29929.1 - 3.1e-23 80.8 12.8 2.1e-05 24.3 0.1 6.4 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.17 EGC29929.1 - 2.4e-05 24.3 0.2 5e-05 23.3 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC29929.1 - 0.00015 22.2 0.2 0.0003 21.2 0.2 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RNase_3_N PF18497.1 EGC29929.1 - 0.18 12.1 4.0 2.1 8.6 0.1 2.5 2 1 0 2 2 2 0 Ribonuclease III N-terminal domain DNA_pol_A PF00476.20 EGC29930.1 - 1.6e-76 257.9 0.1 3.2e-74 250.2 0.0 3.5 2 1 0 2 2 2 1 DNA polymerase family A 5_3_exonuc_N PF02739.16 EGC29930.1 - 5.6e-40 136.8 0.1 1.5e-39 135.4 0.0 1.8 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.20 EGC29930.1 - 3.9e-25 88.3 0.2 2.2e-24 85.8 0.2 2.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.20 EGC29930.1 - 2.9e-14 53.2 0.1 1.1e-13 51.3 0.0 2.0 2 0 0 2 2 2 1 3'-5' exonuclease DUF3070 PF11270.8 EGC29930.1 - 0.0082 16.4 0.6 0.018 15.2 0.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3070) HHH_5 PF14520.6 EGC29930.1 - 0.011 16.3 0.2 0.057 14.0 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix domain Methyltransf_15 PF09445.10 EGC29930.1 - 0.018 14.7 0.8 0.99 9.0 0.0 3.0 3 0 0 3 3 3 0 RNA cap guanine-N2 methyltransferase HHH_2 PF12826.7 EGC29930.1 - 0.034 14.2 0.0 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Lipin_N PF04571.14 EGC29931.1 - 2.1e-10 40.4 0.0 3.2e-10 39.9 0.0 1.2 1 0 0 1 1 1 1 lipin, N-terminal conserved region CDC13_N PF16853.5 EGC29932.1 - 0.043 13.3 0.1 0.051 13.1 0.1 1.0 1 0 0 1 1 1 0 Cell division control protein 13 N-terminus GATA PF00320.27 EGC29933.1 - 1.4e-05 24.6 1.8 3.9e-05 23.2 1.8 1.8 1 0 0 1 1 1 1 GATA zinc finger Importin_rep_4 PF18808.1 EGC29933.1 - 0.19 12.0 0.1 0.19 12.0 0.1 1.9 2 0 0 2 2 2 0 Importin repeat zf-C3HC4_3 PF13920.6 EGC29933.1 - 0.23 11.4 1.7 18 5.2 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CTU2 PF10288.9 EGC29933.1 - 1.5 9.1 4.4 1.2 9.4 0.8 2.6 1 1 1 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 UPF0242 PF06785.11 EGC29935.1 - 0.0012 18.9 5.1 0.0016 18.6 5.1 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Fzo_mitofusin PF04799.13 EGC29935.1 - 0.07 12.7 1.8 0.095 12.3 1.8 1.2 1 0 0 1 1 1 0 fzo-like conserved region SIKE PF05769.11 EGC29935.1 - 0.075 13.0 10.2 0.13 12.2 10.2 1.4 1 1 0 1 1 1 0 SIKE family YlaC PF10777.9 EGC29935.1 - 0.22 11.3 1.2 0.52 10.1 1.2 1.7 1 1 0 1 1 1 0 Inner membrane protein YlaC Pkinase PF00069.25 EGC29938.1 - 0.0031 16.9 0.2 0.013 14.8 0.2 1.8 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29938.1 - 0.13 11.5 0.2 0.72 9.1 0.2 1.8 1 1 1 2 2 2 0 Protein tyrosine kinase TFIIA PF03153.13 EGC29939.1 - 4.6 7.1 29.9 6.2 6.7 29.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 EGC29940.1 - 4.6e-17 61.9 20.7 3.3e-09 36.8 2.3 5.8 4 2 0 4 4 4 3 FNIP Repeat Ribosomal_L21e PF01157.18 EGC29941.1 - 2.2e-43 146.2 1.2 3.1e-43 145.7 1.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Rogdi_lz PF10259.9 EGC29942.1 - 5.6e-10 39.1 7.2 1.3e-08 34.6 7.3 2.7 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein SelP_N PF04592.14 EGC29942.1 - 9.9 5.5 11.3 30 3.9 11.3 1.9 1 0 0 1 1 1 0 Selenoprotein P, N terminal region RNA_pol_L_2 PF13656.6 EGC29943.1 - 9.3e-26 89.4 0.2 1.2e-25 89.1 0.2 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGC29943.1 - 2.1e-06 27.1 0.0 3.1e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain LRR_1 PF00560.33 EGC29944.1 - 0.4 11.4 3.0 9.4 7.2 3.0 3.0 1 1 0 1 1 1 0 Leucine Rich Repeat Pox_RNA_Pol_19 PF05320.12 EGC29944.1 - 0.54 10.2 4.8 0.54 10.2 2.6 1.8 2 0 0 2 2 2 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Ribosomal_S19e PF01090.19 EGC29946.1 - 5.3e-51 171.9 0.0 6e-51 171.7 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e DUF5052 PF16475.5 EGC29947.1 - 0.0012 18.6 0.5 0.0014 18.3 0.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF5052) tRNA_anti-codon PF01336.25 EGC29947.1 - 0.032 14.2 0.1 0.053 13.5 0.1 1.5 1 1 0 1 1 1 0 OB-fold nucleic acid binding domain FNIP PF05725.12 EGC29948.1 - 3.2e-51 171.3 77.0 4.1e-10 39.7 3.8 9.8 3 3 7 11 11 11 10 FNIP Repeat DUF1769 PF08588.10 EGC29948.1 - 0.00074 19.7 1.3 1.2 9.4 0.0 4.3 3 1 0 3 3 3 2 Protein of unknown function (DUF1769) Meth_synt_2 PF01717.18 EGC29949.1 - 1.7e-156 520.5 0.0 2.6e-148 493.6 0.0 2.3 2 0 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.12 EGC29949.1 - 2.4e-110 368.9 0.3 9.6e-101 337.4 0.1 3.9 3 1 0 3 3 3 2 Cobalamin-independent synthase, N-terminal domain URO-D PF01208.17 EGC29949.1 - 0.00037 19.7 0.1 0.0069 15.6 0.0 2.3 2 0 0 2 2 2 1 Uroporphyrinogen decarboxylase (URO-D) Ribosomal_L5 PF00281.19 EGC29950.1 - 1.2e-20 73.6 0.0 2.5e-20 72.6 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L5 Ribosomal_L5_C PF00673.21 EGC29950.1 - 5.1e-20 71.5 0.0 7.9e-20 70.8 0.0 1.4 1 0 0 1 1 1 1 ribosomal L5P family C-terminus RhoGAP PF00620.27 EGC29951.1 - 2e-44 151.1 1.1 2e-44 151.1 1.1 2.6 2 1 0 2 2 2 1 RhoGAP domain HAP1_N PF04849.13 EGC29951.1 - 0.00093 18.5 13.2 0.00093 18.5 13.2 3.4 3 1 0 3 3 3 1 HAP1 N-terminal conserved region Spc7 PF08317.11 EGC29951.1 - 0.0028 16.6 17.0 0.0028 16.6 17.0 4.0 3 1 1 4 4 4 1 Spc7 kinetochore protein zf-C4H2 PF10146.9 EGC29951.1 - 0.0052 17.1 20.4 0.0052 17.1 20.4 2.6 3 0 0 3 3 3 2 Zinc finger-containing protein DUF848 PF05852.11 EGC29951.1 - 0.016 15.3 7.7 0.016 15.3 7.7 3.9 3 1 2 5 5 5 0 Gammaherpesvirus protein of unknown function (DUF848) RAG1_imp_bd PF12560.8 EGC29951.1 - 0.03 13.8 0.5 0.03 13.8 0.5 3.7 3 1 0 4 4 4 0 RAG1 importin binding ERM PF00769.19 EGC29951.1 - 1.6 8.5 52.0 0.29 10.9 15.5 3.1 1 1 0 2 2 2 0 Ezrin/radixin/moesin family Med13_C PF06333.12 EGC29951.1 - 2.2 7.5 8.5 0.1 11.8 2.7 1.6 2 0 0 2 2 2 0 Mediator complex subunit 13 C-terminal domain HOOK PF05622.12 EGC29951.1 - 4.1 5.4 60.0 0.14 10.3 6.9 3.6 3 1 1 4 4 4 0 HOOK protein RGS PF00615.19 EGC29952.1 - 7.5e-16 58.5 0.2 6.7e-13 48.9 0.1 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain DivIC PF04977.15 EGC29953.1 - 0.023 14.4 2.1 0.023 14.4 2.1 3.3 3 1 1 4 4 4 0 Septum formation initiator DUF3450 PF11932.8 EGC29953.1 - 0.75 9.0 8.0 1.5 8.0 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DHR10 PF18595.1 EGC29953.1 - 0.89 9.6 10.1 2.7 8.1 10.1 1.8 1 0 0 1 1 1 0 Designed helical repeat protein 10 domain PLDc_2 PF13091.6 EGC29954.1 - 9.2e-19 67.7 0.9 1.5e-09 37.9 0.4 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGC29954.1 - 1.4e-16 59.9 0.3 2.5e-07 30.6 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif Response_reg PF00072.24 EGC29955.1 - 1.5e-39 134.7 0.2 2.2e-25 89.0 1.1 4.0 4 0 0 4 4 4 3 Response regulator receiver domain HATPase_c PF02518.26 EGC29955.1 - 2.6e-27 95.6 0.0 6.6e-27 94.2 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGC29955.1 - 2.4e-15 56.3 1.4 9e-15 54.5 0.5 2.4 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EGC29955.1 - 4.8e-10 39.4 0.1 1.8e-09 37.6 0.0 2.1 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.7 EGC29955.1 - 1.8e-08 34.6 0.1 1.2e-07 32.0 0.0 2.5 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EGC29955.1 - 6.7e-07 29.5 0.0 1.5e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold REF PF05755.12 EGC29955.1 - 0.00082 19.3 0.0 0.0019 18.0 0.0 1.6 1 0 0 1 1 1 1 Rubber elongation factor protein (REF) PAS_3 PF08447.12 EGC29955.1 - 0.057 13.7 0.0 0.21 11.9 0.0 2.0 2 0 0 2 2 2 0 PAS fold E1_DerP2_DerF2 PF02221.15 EGC29956.1 - 1.1e-23 84.2 0.6 1.2e-23 84.0 0.6 1.0 1 0 0 1 1 1 1 ML domain NDUF_B12 PF08122.12 EGC29957.1 - 2.6e-06 27.4 0.0 3.1e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Mucin PF01456.17 EGC29958.1 - 0.33 10.9 79.6 0.017 15.1 27.5 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein Usp PF00582.26 EGC29959.1 - 2.1e-23 83.4 0.0 3e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 Universal stress protein family E1_DerP2_DerF2 PF02221.15 EGC29960.1 - 1.9e-20 73.7 0.2 2.2e-20 73.5 0.2 1.0 1 0 0 1 1 1 1 ML domain PI3K_1B_p101 PF10486.9 EGC29962.1 - 4.3e-06 24.8 0.2 4.3e-06 24.8 0.2 3.9 4 0 0 4 4 4 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TTD PF12148.8 EGC29962.1 - 0.0052 16.7 0.9 4.5 7.1 0.5 3.0 2 0 0 2 2 2 2 Tandem tudor domain within UHRF1 DDE_Tnp_IS240 PF13610.6 EGC29962.1 - 0.053 13.7 0.0 0.053 13.7 0.0 2.6 3 1 0 3 3 3 0 DDE domain Peptidase_C1 PF00112.23 EGC29963.1 - 1.8e-47 162.2 1.5 3.3e-47 161.4 1.5 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.26 EGC29963.1 - 1.8e-13 51.4 1.2 5.1e-13 50.0 0.4 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.15 EGC29963.1 - 0.021 13.6 0.5 0.66 8.7 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Ras PF00071.22 EGC29964.1 - 1.8e-29 102.4 0.0 3.7e-29 101.4 0.0 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC29964.1 - 2e-17 63.5 0.0 5.1e-17 62.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC29964.1 - 4e-13 49.2 0.0 9.8e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_6 PF13516.6 EGC29964.1 - 3.4e-06 26.7 28.9 0.0035 17.3 0.0 6.1 6 0 0 6 6 6 4 Leucine Rich repeat MMR_HSR1 PF01926.23 EGC29964.1 - 0.0053 16.8 0.0 0.017 15.2 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGC29964.1 - 0.018 14.8 0.1 0.04 13.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain UPA_2 PF17809.1 EGC29964.1 - 0.039 13.8 0.7 4.4 7.1 0.0 2.9 3 0 0 3 3 3 0 UPA domain zf-RING_2 PF13639.6 EGC29966.1 - 1e-09 38.5 10.3 2.4e-09 37.4 10.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC29966.1 - 6.2e-08 32.4 8.9 1.3e-07 31.3 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC29966.1 - 1.3e-07 31.3 10.5 4e-07 29.8 10.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC29966.1 - 2.5e-07 30.4 6.9 5.8e-07 29.3 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC29966.1 - 1e-05 25.7 6.4 4.8e-05 23.6 6.4 2.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC29966.1 - 8.3e-05 22.5 4.8 0.00023 21.1 4.8 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC29966.1 - 0.00057 20.0 8.0 0.0023 18.1 8.0 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC29966.1 - 0.014 15.3 9.4 0.04 13.9 9.4 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC29966.1 - 0.021 14.9 0.9 0.044 13.8 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC29966.1 - 0.037 13.8 9.1 0.079 12.8 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC29966.1 - 0.15 12.2 4.1 0.36 11.0 4.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EGC29966.1 - 0.19 11.9 6.3 0.44 10.7 6.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 EGC29966.1 - 0.38 10.6 7.0 0.86 9.4 7.0 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC29966.1 - 1.1 9.0 5.9 2.1 8.0 5.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Pkinase PF00069.25 EGC29967.1 - 3.3e-25 88.9 0.0 3.6e-25 88.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29967.1 - 2e-17 63.3 0.0 2.3e-17 63.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC29967.1 - 2.2e-05 23.4 0.0 2.4e-05 23.3 0.0 1.0 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC29967.1 - 0.0012 17.9 0.0 0.0012 17.9 0.0 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC29967.1 - 0.0014 18.0 0.0 0.0019 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC29967.1 - 0.013 14.9 0.1 0.016 14.5 0.1 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC29967.1 - 0.015 15.3 0.1 0.019 14.9 0.1 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family RIO1 PF01163.22 EGC29967.1 - 0.044 13.4 0.1 0.054 13.1 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.20 EGC29967.1 - 0.18 11.3 1.2 0.23 11.0 1.2 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rpr2 PF04032.16 EGC29968.1 - 2.6e-06 27.6 5.4 2.6e-06 27.6 5.4 2.7 2 2 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain TINF2_N PF14973.6 EGC29968.1 - 1.5 9.1 4.5 0.73 10.2 1.2 1.8 1 1 1 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus Tyrosinase PF00264.20 EGC29968.1 - 2 8.6 10.6 2.5 8.3 10.6 1.2 1 0 0 1 1 1 0 Common central domain of tyrosinase Menin PF05053.13 EGC29968.1 - 2.3 6.5 13.7 2.9 6.1 13.7 1.1 1 0 0 1 1 1 0 Menin Herpes_UL69 PF05459.12 EGC29969.1 - 0.0071 15.7 1.7 0.0093 15.3 0.2 1.8 2 0 0 2 2 2 1 Herpesvirus transcriptional regulator family RPN7 PF10602.9 EGC29970.1 - 0.26 11.0 0.1 0.26 11.0 0.1 1.7 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Erf4 PF10256.9 EGC29971.1 - 9.6e-07 28.9 0.1 5.7e-06 26.4 0.0 2.0 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Trep_Strep PF09605.10 EGC29971.1 - 0.029 14.3 1.5 1.1 9.2 0.4 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) ABC2_membrane_2 PF12679.7 EGC29971.1 - 0.12 11.7 0.5 0.17 11.1 0.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4064 PF13273.6 EGC29971.1 - 0.98 9.7 5.8 3.2 8.1 5.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) Inhibitor_I29 PF08246.12 EGC29972.1 - 4.1e-13 49.6 9.3 1e-12 48.3 9.3 1.7 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) DUF4771 PF15995.5 EGC29972.1 - 0.03 14.6 0.2 0.042 14.1 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4771) OAD_gamma PF04277.13 EGC29972.1 - 0.3 11.7 0.2 0.3 11.7 0.2 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain FAM165 PF14981.6 EGC29972.1 - 0.54 10.1 2.3 1.1 9.1 2.3 1.4 1 0 0 1 1 1 0 FAM165 family Methyltransf_31 PF13847.6 EGC29973.1 - 4.9e-16 58.9 0.0 8.5e-16 58.1 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29973.1 - 8.9e-15 55.2 0.0 1.6e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC29973.1 - 1.1e-13 51.6 0.0 2e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC29973.1 - 9.3e-11 41.5 0.0 2.9e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGC29973.1 - 1.3e-08 35.5 0.0 2.7e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC29973.1 - 2.5e-07 30.7 0.0 6.9e-07 29.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.12 EGC29973.1 - 0.00086 19.1 0.0 0.0012 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) MTS PF05175.14 EGC29973.1 - 0.001 18.6 0.0 0.0032 17.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_16 PF10294.9 EGC29973.1 - 0.011 15.5 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Methyltransf_4 PF02390.17 EGC29973.1 - 0.027 13.9 0.0 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase TMEM131_like PF12371.8 EGC29974.1 - 1.6e-17 63.5 1.0 1.6e-17 63.5 1.0 6.1 7 0 0 7 7 7 1 Transmembrane protein 131-like DUF4203 PF13886.6 EGC29974.1 - 0.059 13.0 0.2 0.096 12.3 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4203) L-fibroin PF05849.11 EGC29976.1 - 0.067 12.5 0.0 0.092 12.0 0.0 1.2 1 0 0 1 1 1 0 Fibroin light chain (L-fibroin) OTU PF02338.19 EGC29977.1 - 4.3e-12 46.6 0.0 4.3e-12 46.6 0.0 3.2 2 1 0 2 2 2 1 OTU-like cysteine protease Presenilin PF01080.17 EGC29977.1 - 0.017 13.9 8.9 0.022 13.5 8.9 1.3 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC29977.1 - 0.23 11.4 44.2 0.3 11.0 44.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 EGC29977.1 - 2.4 7.9 17.0 3.9 7.2 17.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LMBR1 PF04791.16 EGC29977.1 - 3.7 6.4 13.3 7.1 5.4 13.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Vac7 PF12751.7 EGC29977.1 - 6.1 6.2 9.8 8.2 5.8 9.8 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 DDHD PF02862.17 EGC29978.1 - 1.1e-32 114.0 1.2 2.8e-32 112.7 1.2 1.7 1 0 0 1 1 1 1 DDHD domain DUF676 PF05057.14 EGC29978.1 - 0.00011 21.8 0.0 0.18 11.3 0.0 2.5 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGC29978.1 - 0.07 12.4 0.1 2.6 7.2 0.0 2.8 3 0 0 3 3 3 0 Serine aminopeptidase, S33 Androgen_recep PF02166.16 EGC29978.1 - 0.16 10.8 1.9 0.3 9.9 1.9 1.4 1 0 0 1 1 1 0 Androgen receptor Spc7_N PF15402.6 EGC29978.1 - 0.41 8.8 19.9 0.61 8.3 19.9 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 NOA36 PF06524.12 EGC29978.1 - 0.48 9.7 6.6 0.85 8.9 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EGC29978.1 - 1.4 8.6 11.2 2.8 7.6 11.2 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein ApoA-II PF04711.13 EGC29979.1 - 0.0097 16.0 0.5 0.056 13.6 0.2 2.4 2 0 0 2 2 2 1 Apolipoprotein A-II (ApoA-II) PhaP_Bmeg PF09602.10 EGC29979.1 - 0.021 14.8 6.5 0.26 11.2 2.5 2.5 2 0 0 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) POX PF07526.11 EGC29980.1 - 0.095 13.3 7.6 0.23 12.0 0.3 2.8 3 0 0 3 3 3 0 Associated with HOX Secretin_N_2 PF07655.13 EGC29980.1 - 0.18 12.4 28.6 1.1 9.8 13.9 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain ALMT PF11744.8 EGC29980.1 - 3 6.6 8.6 2.6 6.8 0.9 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter RasGEF PF00617.19 EGC29981.1 - 1e-43 149.6 3.6 1e-43 149.6 3.6 3.3 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC29981.1 - 1e-20 73.9 0.7 1e-20 73.9 0.7 4.4 5 0 0 5 5 5 1 RasGEF N-terminal motif zf-B_box PF00643.24 EGC29981.1 - 8.3e-10 38.7 4.4 8.3e-10 38.7 4.4 2.7 2 1 1 3 3 3 1 B-box zinc finger zf-RING_UBOX PF13445.6 EGC29981.1 - 5.2e-08 32.8 10.3 5.2e-08 32.8 10.3 3.0 3 0 0 3 3 3 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC29981.1 - 8.6e-07 28.7 9.8 8.6e-07 28.7 9.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC29981.1 - 1.1e-06 28.4 9.2 1.1e-06 28.4 9.2 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC29981.1 - 4e-06 26.7 9.6 4e-06 26.7 9.6 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_10 PF16685.5 EGC29981.1 - 7.5e-06 26.0 8.1 7.5e-06 26.0 8.1 3.0 3 0 0 3 3 3 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC29981.1 - 1.6e-05 25.0 9.6 1.6e-05 25.0 9.6 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGC29981.1 - 9.7e-05 22.6 8.7 9.7e-05 22.6 8.7 2.6 2 0 0 2 2 2 1 Ring finger domain HU-CCDC81_bac_2 PF18175.1 EGC29981.1 - 0.00056 19.7 0.3 0.0016 18.3 0.3 1.8 1 0 0 1 1 1 1 CCDC81-like prokaryotic HU domain 2 Prok-RING_4 PF14447.6 EGC29981.1 - 0.01 15.7 7.4 0.01 15.7 7.4 2.4 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC29981.1 - 0.052 13.3 3.4 0.15 11.9 3.4 1.9 1 0 0 1 1 1 0 RING-like zinc finger HSP33 PF01430.19 EGC29981.1 - 0.056 12.8 0.3 0.17 11.3 0.3 1.8 1 0 0 1 1 1 0 Hsp33 protein IBR PF01485.21 EGC29981.1 - 1.2 9.4 12.4 3.5 7.9 0.3 3.0 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-RING_6 PF14835.6 EGC29981.1 - 3.7 7.5 10.7 0.04 13.8 2.4 2.0 2 0 0 2 2 1 0 zf-RING of BARD1-type protein Rpr2 PF04032.16 EGC29983.1 - 1.4e-19 70.2 0.4 1.5e-19 70.0 0.4 1.0 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DAGAT PF03982.13 EGC29984.1 - 2.2e-110 368.2 0.0 2.6e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase Antimicrobial_8 PF08103.11 EGC29984.1 - 0.43 10.8 0.0 0.43 10.8 0.0 2.1 2 0 0 2 2 2 0 Uperin family NUDIX PF00293.28 EGC29985.1 - 7.8e-06 26.0 0.2 0.0013 18.8 0.0 3.1 1 1 1 2 2 2 2 NUDIX domain Spa1_C PF18218.1 EGC29985.1 - 0.043 14.2 0.2 0.11 13.0 0.2 1.7 1 0 0 1 1 1 0 Lantibiotic immunity protein Spa1 C-terminal domain Surp PF01805.20 EGC29985.1 - 0.051 13.6 0.2 0.15 12.0 0.2 1.8 1 0 0 1 1 1 0 Surp module VWC PF00093.18 EGC29986.1 - 0.042 14.2 24.4 0.14 12.5 9.6 2.4 2 0 0 2 2 2 0 von Willebrand factor type C domain MetOD1 PF18546.1 EGC29988.1 - 0.23 11.4 3.8 0.58 10.1 0.1 3.4 2 1 1 3 3 3 0 Metanogen output domain 1 Methyltransf_11 PF08241.12 EGC29989.1 - 3.5e-17 62.8 0.0 5.8e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC29989.1 - 1.1e-14 54.9 0.0 6.2e-14 52.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC29989.1 - 6.6e-09 35.8 0.0 9.1e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC29989.1 - 7.3e-09 36.3 0.0 2.9e-08 34.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC29989.1 - 5.1e-08 32.9 0.1 1.4e-07 31.4 0.1 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC29989.1 - 0.00026 20.4 0.0 0.00038 19.8 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EGC29989.1 - 0.00058 19.8 0.0 0.0066 16.3 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.14 EGC29989.1 - 0.012 15.1 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_PK PF05891.12 EGC29989.1 - 0.013 15.0 0.0 0.021 14.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Cons_hypoth95 PF03602.15 EGC29989.1 - 0.025 14.2 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Myotub-related PF06602.14 EGC29990.1 - 2.6e-124 414.7 3.1 3.1e-124 414.5 3.1 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.20 EGC29990.1 - 0.0063 16.3 0.1 0.013 15.3 0.1 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGC29990.1 - 0.062 13.3 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family Prokineticin PF06607.11 EGC29990.1 - 0.16 12.3 0.0 30 5.0 0.0 2.5 2 0 0 2 2 2 0 Prokineticin Peptidase_M1 PF01433.20 EGC29991.1 - 3.9e-44 150.8 0.0 6.6e-44 150.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M1 domain Leuk-A4-hydro_C PF09127.11 EGC29991.1 - 1.6e-39 134.5 0.2 3.2e-39 133.5 0.2 1.6 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_M1_N PF17900.1 EGC29991.1 - 4.6e-26 92.1 1.1 1.2e-25 90.8 0.4 1.9 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain SprT-like PF10263.9 EGC29991.1 - 0.15 11.9 0.0 1.3 8.9 0.0 2.3 2 0 0 2 2 2 0 SprT-like family p450 PF00067.22 EGC29994.1 - 2e-81 274.1 0.4 2.4e-81 273.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGC29995.1 - 1.2e-15 57.7 0.2 3.2e-15 56.2 0.2 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC29995.1 - 7.5e-11 41.8 0.1 2.8e-10 39.9 0.1 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase FAD-oxidase_C PF02913.19 EGC29997.1 - 1.8e-53 181.8 0.0 2.3e-53 181.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGC29997.1 - 2.7e-37 127.6 0.0 4.1e-37 127.0 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain ANF_receptor PF01094.28 EGC29997.1 - 0.0028 16.8 0.0 0.012 14.7 0.0 1.8 1 1 0 2 2 2 1 Receptor family ligand binding region CUE PF02845.16 EGC29998.1 - 1.1e-05 25.1 0.0 2.1e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 CUE domain RTBV_P46 PF06216.11 EGC29999.1 - 0.0092 14.9 0.0 0.015 14.2 0.0 1.3 1 1 0 1 1 1 1 Rice tungro bacilliform virus P46 protein Dimer_Tnp_hAT PF05699.14 EGC30000.1 - 2.9e-12 46.2 0.3 7.1e-12 45.0 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MCM3AP_GANP PF16769.5 EGC30000.1 - 0.0032 15.8 2.5 0.0038 15.6 2.5 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP CDC37_C PF08564.10 EGC30000.1 - 0.027 14.6 0.5 0.049 13.8 0.5 1.3 1 0 0 1 1 1 0 Cdc37 C terminal domain WRNPLPNID PF15017.6 EGC30000.1 - 0.077 13.9 1.7 0.077 13.9 1.7 1.8 1 1 0 1 1 1 0 Putative WW-binding domain and destruction box APG17 PF04108.12 EGC30001.1 - 3.3e-26 92.3 33.1 1.4e-14 54.0 5.6 2.2 2 0 0 2 2 2 2 Autophagy protein Apg17 MIT PF04212.18 EGC30001.1 - 1.8 8.7 6.5 1.1 9.4 0.6 3.2 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain DASH_Dam1 PF08653.10 EGC30001.1 - 4.7 7.1 14.6 16 5.4 1.2 4.5 3 1 1 4 4 4 0 DASH complex subunit Dam1 Pam16 PF03656.13 EGC30002.1 - 2.7e-12 46.8 0.3 3.2e-12 46.6 0.3 1.1 1 0 0 1 1 1 1 Pam16 Kelch_6 PF13964.6 EGC30003.1 - 1.8e-11 43.9 3.8 9.6e-07 28.9 0.1 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.25 EGC30003.1 - 3.2e-07 29.8 10.0 0.0066 16.0 0.1 5.2 6 0 0 6 6 6 2 Kelch motif Kelch_4 PF13418.6 EGC30003.1 - 1.2e-06 28.4 2.5 0.012 15.6 0.0 4.4 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-C3HC4 PF00097.25 EGC30003.1 - 5.3e-06 26.2 9.5 5.3e-06 26.2 9.5 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Kelch_5 PF13854.6 EGC30003.1 - 6.5e-06 26.0 1.7 0.039 13.9 0.1 3.6 3 0 0 3 3 3 1 Kelch motif zf-C3HC4_2 PF13923.6 EGC30003.1 - 1.5e-05 24.7 9.5 1.5e-05 24.7 9.5 3.0 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.15 EGC30003.1 - 5e-05 23.1 2.6 0.91 9.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Prok-RING_4 PF14447.6 EGC30003.1 - 0.00063 19.5 9.2 0.00063 19.5 9.2 2.1 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC30003.1 - 0.0022 18.0 10.0 0.0029 17.6 5.4 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGC30003.1 - 0.0044 17.1 5.2 0.0044 17.1 5.2 3.0 3 0 0 3 3 2 1 zinc RING finger of MSL2 zf-RING_2 PF13639.6 EGC30003.1 - 0.0049 17.2 8.6 0.0049 17.2 8.6 2.9 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGC30003.1 - 0.0072 16.5 10.1 0.0072 16.5 10.1 3.4 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC30003.1 - 0.0092 15.8 3.6 0.0092 15.8 3.6 2.1 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-B_box PF00643.24 EGC30003.1 - 0.027 14.6 0.2 0.027 14.6 0.2 3.1 3 0 0 3 3 2 0 B-box zinc finger Kelch_3 PF13415.6 EGC30003.1 - 0.039 14.3 0.1 0.89 9.9 0.1 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-MIZ PF02891.20 EGC30003.1 - 0.052 13.3 7.3 0.14 11.9 7.3 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Polo_box_3 PF18544.1 EGC30003.1 - 0.26 12.0 2.0 2.5 8.8 0.0 2.8 2 1 0 2 2 2 0 Polo box domain zf-RING_5 PF14634.6 EGC30003.1 - 0.27 11.2 11.6 0.098 12.6 7.3 2.5 2 0 0 2 2 2 0 zinc-RING finger domain 7TM_GPCR_Str PF10326.9 EGC30004.1 - 0.14 11.5 1.0 2.9 7.2 0.5 2.0 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Str TCR PF03638.15 EGC30006.1 - 6.6e-22 77.5 63.5 8.8e-13 48.3 23.8 2.4 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain MSL2-CXC PF16682.5 EGC30006.1 - 1.4 9.1 53.1 4.8 7.4 24.8 3.4 2 2 1 3 3 3 0 CXC domain of E3 ubiquitin-protein ligase MSL2 TFIIA PF03153.13 EGC30006.1 - 7.9 6.4 45.1 0.14 12.1 32.1 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kelch_4 PF13418.6 EGC30007.1 - 6.1e-36 122.2 19.7 3.1e-08 33.5 0.0 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC30007.1 - 2.5e-30 104.1 15.6 7.9e-07 29.2 0.2 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC30007.1 - 3.2e-29 100.4 4.3 1.6e-08 34.3 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGC30007.1 - 1.2e-26 92.1 8.8 3.2e-09 36.2 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGC30007.1 - 3.1e-24 84.4 10.2 3.9e-06 26.9 0.0 6.2 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC30007.1 - 3.1e-16 58.6 5.2 7.1e-08 32.1 0.0 5.9 6 0 0 6 6 6 3 Kelch motif CHAP PF05257.16 EGC30007.1 - 0.053 14.1 1.3 5.2 7.7 0.1 3.8 4 1 0 4 4 4 0 CHAP domain DUF3672 PF12421.8 EGC30007.1 - 0.27 11.1 1.5 13 5.7 0.1 3.0 3 0 0 3 3 3 0 Fibronectin type III protein Syja_N PF02383.18 EGC30008.1 - 3.9e-80 269.6 0.3 3.9e-80 269.6 0.3 3.0 2 1 0 2 2 2 1 SacI homology domain WYL PF13280.6 EGC30008.1 - 0.062 13.4 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 WYL domain SNF5 PF04855.12 EGC30009.1 - 2e-28 99.8 0.1 2e-28 99.8 0.1 3.8 2 2 0 2 2 2 1 SNF5 / SMARCB1 / INI1 TFIIF_alpha PF05793.12 EGC30010.1 - 9e-21 74.0 76.8 4.1e-18 65.3 5.9 2.6 1 1 2 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FSA_C PF10479.9 EGC30010.1 - 0.11 10.6 7.0 0.17 10.0 7.0 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Nop14 PF04147.12 EGC30010.1 - 7.8 4.6 54.8 13 3.8 54.8 1.4 1 0 0 1 1 1 0 Nop14-like family Coiled PF05710.12 EGC30011.1 - 0.01 16.7 5.7 0.016 16.0 5.7 1.4 1 1 0 1 1 1 0 Coiled coil CBM_X2 PF03442.14 EGC30011.1 - 0.021 14.9 1.9 0.023 14.8 1.9 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Cyt-b5 PF00173.28 EGC30012.1 - 1.1e-20 73.5 0.1 2.2e-20 72.6 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain FA_hydroxylase PF04116.13 EGC30012.1 - 1.3e-12 48.2 20.6 1.3e-12 48.2 20.6 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF4419 PF14388.6 EGC30013.1 - 1.8e-09 37.4 0.2 6.4e-08 32.4 0.0 2.4 2 1 1 3 3 3 2 Domain of unknown function (DUF4419) Utp14 PF04615.13 EGC30014.1 - 5e-134 448.6 100.5 5e-134 448.6 100.5 2.2 1 1 1 2 2 2 1 Utp14 protein DUF3040 PF11239.8 EGC30014.1 - 7.4 6.9 4.8 2.2 8.6 0.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) OTU PF02338.19 EGC30015.1 - 1.2e-24 87.2 0.1 1.2e-24 87.2 0.1 1.8 2 1 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGC30015.1 - 1.5e-10 41.0 0.5 1.5e-10 41.0 0.5 3.2 1 1 2 3 3 3 1 Peptidase C65 Otubain DUF3050 PF11251.8 EGC30015.1 - 0.018 14.7 0.0 0.052 13.2 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3050) CDC45 PF02724.14 EGC30015.1 - 1.3 7.2 19.0 1.9 6.7 19.0 1.3 1 0 0 1 1 1 0 CDC45-like protein Exonuc_VII_L PF02601.15 EGC30015.1 - 2.1 7.9 9.0 2.7 7.5 9.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF4407 PF14362.6 EGC30015.1 - 7.1 5.9 11.5 11 5.3 11.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PCRF PF03462.18 EGC30015.1 - 8.8 6.1 17.2 0.38 10.6 9.6 2.4 1 1 2 3 3 3 0 PCRF domain Interfer-bind PF09294.10 EGC30016.1 - 0.0062 16.8 1.0 0.017 15.4 1.0 1.7 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III G_path_suppress PF15991.5 EGC30017.1 - 1.3 9.1 8.5 0.065 13.4 2.3 2.0 2 1 0 2 2 2 0 G-protein pathway suppressor ACOX PF01756.19 EGC30018.1 - 1.3e-25 90.0 0.0 3.4e-25 88.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGC30018.1 - 6.4e-14 51.9 0.0 1.2e-13 51.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC30018.1 - 1.9e-05 24.9 0.0 3.4e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Toxin_5 PF05294.13 EGC30018.1 - 0.051 14.0 1.1 0.13 12.8 1.1 1.7 1 0 0 1 1 1 0 Scorpion short toxin Tfb5 PF06331.12 EGC30019.1 - 4.7e-22 77.7 0.2 5.3e-22 77.6 0.2 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DEAD PF00270.29 EGC30019.1 - 0.0029 17.4 0.1 0.0032 17.2 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGC30019.1 - 0.048 12.9 0.3 0.05 12.8 0.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_22 PF13401.6 EGC30019.1 - 0.11 12.7 0.1 0.13 12.6 0.1 1.1 1 0 0 1 1 1 0 AAA domain Pan3_PK PF18101.1 EGC30020.1 - 3.4e-60 202.0 0.2 5.2e-60 201.4 0.2 1.3 1 0 0 1 1 1 1 Pan3 Pseudokinase domain Pkinase PF00069.25 EGC30020.1 - 6.1e-11 42.2 0.0 1.1e-10 41.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30020.1 - 0.0033 16.7 0.0 0.005 16.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RNase_PH_C PF03725.15 EGC30020.1 - 0.15 12.1 0.0 0.38 10.8 0.0 1.7 1 0 0 1 1 1 0 3' exoribonuclease family, domain 2 Roughex PF06020.11 EGC30022.1 - 0.23 10.5 5.1 0.37 9.9 5.1 1.4 1 0 0 1 1 1 0 Drosophila roughex protein SOG2 PF10428.9 EGC30022.1 - 2.9 7.0 24.0 3.6 6.7 24.0 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein CobT PF06213.12 EGC30022.1 - 3.1 7.1 9.9 4.4 6.6 9.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Androgen_recep PF02166.16 EGC30022.1 - 3.6 6.3 18.2 6.1 5.6 18.2 1.4 1 0 0 1 1 1 0 Androgen receptor DRIM PF07539.12 EGC30023.1 - 6.7e-104 348.4 16.2 6.7e-104 348.4 16.2 4.4 4 1 1 5 5 5 1 Down-regulated in metastasis CDC45 PF02724.14 EGC30023.1 - 0.00068 18.1 5.5 0.00068 18.1 5.5 3.5 3 1 0 3 3 3 2 CDC45-like protein HEAT PF02985.22 EGC30023.1 - 0.017 15.3 0.0 3.1e+02 2.1 0.0 6.1 6 0 0 6 6 6 0 HEAT repeat YgbB PF02542.16 EGC30023.1 - 0.16 12.2 0.1 0.67 10.2 0.1 2.1 1 0 0 1 1 1 0 YgbB family NUC173 PF08161.12 EGC30023.1 - 1 9.0 11.5 4.4 6.9 0.1 6.1 7 0 0 7 7 7 0 NUC173 domain Ribosomal_L31e PF01198.19 EGC30024.1 - 2.8e-38 130.0 1.1 3.5e-38 129.7 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Topoisom_I PF01028.20 EGC30025.1 - 9.6e-92 306.4 2.8 9.6e-92 306.4 2.8 2.3 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topoisom_I_N PF02919.15 EGC30025.1 - 1.1e-91 306.1 1.2 1.1e-91 306.1 1.2 2.8 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topo_C_assoc PF14370.6 EGC30025.1 - 4e-29 100.3 1.5 4e-29 100.3 1.5 2.2 2 0 0 2 2 2 1 C-terminal topoisomerase domain AAA_17 PF13207.6 EGC30025.1 - 0.84 10.1 5.6 0.68 10.4 2.3 2.5 2 0 0 2 2 2 0 AAA domain EAP30 PF04157.16 EGC30026.1 - 1.7e-69 233.7 0.6 2e-69 233.5 0.6 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TFIIE_alpha PF02002.17 EGC30026.1 - 0.0036 17.1 0.1 0.01 15.7 0.1 1.9 1 0 0 1 1 1 1 TFIIE alpha subunit DUF2316 PF10078.9 EGC30026.1 - 0.015 15.5 3.6 0.63 10.3 0.2 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Exonuc_VII_L PF02601.15 EGC30026.1 - 0.017 14.7 0.1 0.033 13.8 0.1 1.4 1 1 0 1 1 1 0 Exonuclease VII, large subunit Enkurin PF13864.6 EGC30026.1 - 0.073 13.5 1.5 4.1 7.9 0.0 2.6 2 0 0 2 2 2 0 Calmodulin-binding PNRC PF15365.6 EGC30027.1 - 1.5e-08 34.2 3.3 4.9e-08 32.6 3.3 2.0 1 0 0 1 1 1 1 Proline-rich nuclear receptor coactivator motif V_ATPase_I PF01496.19 EGC30027.1 - 0.12 10.3 4.2 0.13 10.1 4.2 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family tRNA-synt_2b PF00587.25 EGC30028.1 - 1.1e-30 107.0 0.0 1.5e-27 96.7 0.0 3.0 2 1 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGC30028.1 - 1.5e-10 41.3 7.3 1.5e-10 41.3 7.3 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Pil1 PF13805.6 EGC30028.1 - 0.0014 18.2 0.6 0.0024 17.4 0.6 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 Rab_bind PF16704.5 EGC30028.1 - 0.19 11.8 0.9 0.52 10.4 0.9 1.7 1 0 0 1 1 1 0 Rab binding domain UBA_3 PF09288.10 EGC30028.1 - 1 9.2 6.4 4.4 7.2 3.3 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain SusD-like_3 PF14322.6 EGC30029.1 - 0.4 11.0 3.7 7.3 6.9 0.1 3.1 2 0 0 2 2 2 0 Starch-binding associating with outer membrane DUF4506 PF14958.6 EGC30030.1 - 1.1e-09 38.0 0.4 2.1e-09 37.0 0.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) WD40_4 PF16300.5 EGC30031.1 - 2.7e-40 136.0 1.0 2.3e-21 75.4 0.1 2.5 2 0 0 2 2 2 2 Type of WD40 repeat DUF1899 PF08953.11 EGC30031.1 - 1.5e-39 133.7 4.7 3.6e-19 68.4 0.2 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) WD40 PF00400.32 EGC30031.1 - 1.6e-28 98.3 13.1 7.8e-05 23.4 0.1 9.2 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30031.1 - 1.2e-06 28.7 0.2 0.47 10.8 0.1 5.6 3 2 2 6 6 6 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC30031.1 - 0.0071 15.0 6.2 0.028 13.1 0.3 3.6 3 1 0 3 3 3 1 Nucleoporin Nup120/160 DUF1652 PF07865.11 EGC30031.1 - 0.011 15.5 0.0 0.05 13.4 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) PQQ_2 PF13360.6 EGC30031.1 - 0.075 12.6 0.1 0.25 10.9 0.0 2.0 2 0 0 2 2 2 0 PQQ-like domain Cpn60_TCP1 PF00118.24 EGC30032.1 - 7e-37 127.2 0.2 1.9e-20 73.0 0.0 3.3 2 1 1 3 3 3 3 TCP-1/cpn60 chaperonin family zf-CHCC PF10276.9 EGC30033.1 - 9.2e-17 60.8 1.0 1.2e-16 60.4 1.0 1.2 1 0 0 1 1 1 1 Zinc-finger domain SNF2_N PF00176.23 EGC30034.1 - 7.1e-59 199.3 4.2 1.8e-58 197.9 4.2 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC30034.1 - 3.5e-20 72.4 0.5 1.5e-19 70.4 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC30034.1 - 3e-06 27.1 0.0 1e-05 25.4 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGC30034.1 - 0.00028 20.2 0.1 0.00028 20.2 0.1 3.5 3 0 0 3 3 3 1 ERCC3/RAD25/XPB C-terminal helicase PhoH PF02562.16 EGC30034.1 - 0.071 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein FAD-oxidase_C PF02913.19 EGC30035.1 - 3.8e-56 190.5 0.0 4.9e-56 190.1 0.0 1.1 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGC30035.1 - 4.1e-34 117.3 0.4 6.1e-34 116.7 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Colicin_V PF02674.16 EGC30036.1 - 0.021 14.8 1.2 0.021 14.8 1.2 1.5 2 0 0 2 2 2 0 Colicin V production protein Gti1_Pac2 PF09729.9 EGC30036.1 - 0.034 14.2 1.2 0.044 13.9 1.2 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF5531 PF17671.1 EGC30036.1 - 0.036 14.0 0.6 0.059 13.3 0.1 1.7 1 1 1 2 2 2 0 Family of unknown function (DUF5531) ATP-synt_I PF03899.15 EGC30036.1 - 0.095 13.1 3.3 0.13 12.6 3.3 1.2 1 0 0 1 1 1 0 ATP synthase I chain Ctr PF04145.15 EGC30036.1 - 0.32 11.6 4.5 0.23 12.1 0.3 2.0 1 1 1 2 2 2 0 Ctr copper transporter family DUF2929 PF11151.8 EGC30036.1 - 0.73 10.2 8.0 23 5.4 8.0 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2929) DUF4834 PF16118.5 EGC30036.1 - 1.6 9.7 9.9 9.3 7.3 9.9 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) PTH2 PF01981.16 EGC30037.1 - 3.5e-43 146.6 0.5 3.9e-43 146.5 0.5 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 SCAPER_N PF16501.5 EGC30037.1 - 0.089 12.8 0.1 0.14 12.2 0.1 1.4 1 1 0 1 1 1 0 S phase cyclin A-associated protein in the endoplasmic reticulum Ribosomal_L7Ae PF01248.26 EGC30038.1 - 1.7e-22 79.0 1.4 1.7e-22 79.0 1.4 1.9 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family CCDC168_N PF15804.5 EGC30039.1 - 0.02 14.8 1.0 0.03 14.2 0.5 1.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 168 Tab2_like PF06485.11 EGC30039.1 - 0.022 14.3 0.3 0.027 14.0 0.3 1.1 1 0 0 1 1 1 0 RNA-binding protein Tab2/Atab2 Csm1_N PF18504.1 EGC30039.1 - 0.47 10.8 7.2 1.2 9.5 1.6 2.6 2 0 0 2 2 2 0 Csm1 N-terminal domain 4HBT PF03061.22 EGC30040.1 - 0.049 14.0 0.0 0.075 13.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT PF03061.22 EGC30041.1 - 1.8e-05 25.0 0.0 2.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily GYF PF02213.16 EGC30041.1 - 0.087 12.5 0.1 0.14 11.9 0.1 1.3 1 0 0 1 1 1 0 GYF domain 4HBT_3 PF13622.6 EGC30041.1 - 0.13 12.5 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Thioesterase-like superfamily DUF3627 PF12299.8 EGC30041.1 - 0.9 9.7 7.0 1.7 8.8 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3627) PEX11 PF05648.14 EGC30042.1 - 5.5e-18 65.3 8.3 1.2e-07 31.4 1.7 3.3 2 1 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) CNH PF00780.22 EGC30043.1 - 3.8e-32 112.0 2.0 3.8e-32 112.0 2.0 1.9 2 0 0 2 2 2 1 CNH domain Vps39_2 PF10367.9 EGC30043.1 - 5.5e-29 100.8 0.1 5.5e-29 100.8 0.1 2.7 2 1 1 3 3 3 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.20 EGC30043.1 - 1.4e-07 31.5 30.1 6.1e-05 22.9 6.7 4.8 5 1 1 6 6 6 3 Region in Clathrin and VPS Vps39_1 PF10366.9 EGC30043.1 - 0.00067 19.9 0.1 0.00067 19.9 0.1 5.1 4 1 0 5 5 5 1 Vacuolar sorting protein 39 domain 1 DUF2685 PF10886.8 EGC30043.1 - 0.052 13.8 0.1 0.052 13.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2685) Phage_P2_GpU PF06995.11 EGC30043.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.1 2 0 0 2 2 2 0 Phage P2 GpU DUF202 PF02656.15 EGC30044.1 - 0.0049 17.3 0.2 0.0076 16.7 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) EBP50_C PF09007.11 EGC30044.1 - 8.5 7.4 13.4 14 6.7 0.4 2.3 2 0 0 2 2 2 0 EBP50, C-terminal Asp PF00026.23 EGC30045.1 - 5.8e-44 150.8 0.0 1.8e-43 149.2 0.0 1.6 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGC30045.1 - 4.7e-19 69.3 0.3 6.5e-19 68.8 0.3 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGC30045.1 - 4.4e-13 49.3 0.0 1.5e-12 47.6 0.0 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGC30045.1 - 0.011 16.2 0.0 1 10.0 0.0 2.6 3 0 0 3 3 3 0 gag-polyprotein putative aspartyl protease WD40 PF00400.32 EGC30046.1 - 1.8e-14 53.9 14.1 8.9e-06 26.4 0.1 6.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30046.1 - 3.7e-07 30.3 0.6 2.4 8.5 0.0 5.1 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Acetyltransf_1 PF00583.25 EGC30047.1 - 5e-10 39.6 0.0 7e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.10 EGC30047.1 - 5.1e-07 29.6 0.0 2.3e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_3 PF13302.7 EGC30047.1 - 1.4e-06 29.0 0.0 1.8e-06 28.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC30047.1 - 2.2e-05 24.4 0.0 2.9e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC30047.1 - 3.1e-05 24.3 0.0 5.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC30047.1 - 0.0076 15.7 0.3 0.018 14.5 0.1 1.5 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_4 PF13420.7 EGC30047.1 - 0.025 14.7 0.3 0.032 14.3 0.3 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC30048.1 - 2e-15 57.1 0.0 2.7e-15 56.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC30048.1 - 2.8e-07 30.9 0.2 7.1e-07 29.6 0.1 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC30048.1 - 7.8e-07 29.0 0.1 1.6e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGC30048.1 - 2.9e-06 27.2 0.0 4e-06 26.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC30048.1 - 8.9e-06 26.4 0.0 1e-05 26.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC30048.1 - 1.6e-05 25.1 0.7 2e-05 24.7 0.7 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC30048.1 - 0.0028 17.2 1.0 0.0042 16.6 0.9 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGC30048.1 - 0.026 14.7 0.0 0.049 13.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_1 PF00583.25 EGC30049.1 - 4.1e-13 49.6 0.0 5.6e-13 49.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC30049.1 - 4.6e-09 36.3 0.0 8.1e-09 35.5 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC30049.1 - 5.2e-08 32.8 0.0 8.8e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.7 EGC30049.1 - 7.9e-08 32.6 0.0 1.4e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC30049.1 - 2.2e-05 24.5 0.0 4.5e-05 23.5 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_3 PF13302.7 EGC30049.1 - 9.3e-05 23.1 0.0 0.00012 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC30049.1 - 0.00035 20.1 0.1 0.00037 20.0 0.1 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_13 PF13880.6 EGC30049.1 - 0.019 14.9 0.0 0.039 13.9 0.0 1.6 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase JHD PF17811.1 EGC30049.1 - 0.13 12.8 0.6 0.26 11.8 0.6 1.4 1 0 0 1 1 1 0 Jumonji helical domain MMR_HSR1 PF01926.23 EGC30050.1 - 7.1e-07 29.3 1.1 3.8e-05 23.7 1.1 3.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGC30050.1 - 1.7e-06 27.5 8.2 0.00065 19.1 0.9 3.8 3 0 0 3 3 3 2 AIG1 family GTP_EFTU PF00009.27 EGC30050.1 - 9.6e-05 22.0 0.2 0.00043 19.9 0.2 2.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EGC30050.1 - 0.0013 18.3 1.2 0.0034 16.9 0.1 2.3 2 0 0 2 2 2 1 P-loop containing dynein motor region T2SSE PF00437.20 EGC30050.1 - 0.004 16.3 0.5 0.017 14.2 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGC30050.1 - 0.0049 16.3 0.0 0.011 15.2 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA PF00004.29 EGC30050.1 - 0.0059 17.0 0.5 0.073 13.5 0.5 3.0 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGC30050.1 - 0.0075 15.5 0.0 0.019 14.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) SRP54 PF00448.22 EGC30050.1 - 0.019 14.6 0.0 0.054 13.1 0.0 1.8 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.18 EGC30050.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.6 EGC30050.1 - 0.055 13.7 0.1 0.88 9.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain Putative_G5P PF17426.2 EGC30050.1 - 0.061 13.4 0.7 0.31 11.1 0.0 2.6 3 0 0 3 3 1 0 Putative Gamma DNA binding protein G5P Sigma54_activat PF00158.26 EGC30050.1 - 0.066 12.9 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_19 PF13245.6 EGC30050.1 - 0.13 12.6 0.0 1.3 9.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain Cyclin_N PF00134.23 EGC30051.1 - 3.6e-12 46.1 0.2 6.2e-12 45.4 0.2 1.3 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGC30051.1 - 7.9e-09 36.1 0.0 1.5e-08 35.2 0.0 1.4 1 1 0 1 1 1 1 Cyclin HATPase_c PF02518.26 EGC30052.1 - 7.9e-28 97.2 0.0 2e-27 95.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC30052.1 - 5.8e-23 81.2 0.6 1.3e-22 80.0 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGC30052.1 - 1.2e-17 63.7 0.1 1.2e-17 63.7 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Macoilin PF09726.9 EGC30052.1 - 0.42 9.1 47.7 0.71 8.4 47.7 1.3 1 0 0 1 1 1 0 Macoilin family DUF4118 PF13493.6 EGC30052.1 - 0.7 9.7 3.9 1 9.1 2.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) VIT1 PF01988.19 EGC30052.1 - 6.4 6.6 16.8 0.34 10.8 7.1 3.1 2 1 1 3 3 3 0 VIT family ELMO_CED12 PF04727.13 EGC30053.1 - 1.6e-43 148.9 2.4 1.6e-43 148.9 2.4 1.7 2 0 0 2 2 2 1 ELMO/CED-12 family TolA_bind_tri PF16331.5 EGC30053.1 - 0.36 10.9 5.6 5.2 7.2 0.8 2.6 1 1 1 2 2 2 0 TolA binding protein trimerisation Opiods_neuropep PF01160.18 EGC30054.1 - 7.2e-05 22.8 17.2 1.3 9.1 0.5 5.8 5 0 0 5 5 5 4 Vertebrate endogenous opioids neuropeptide Rap_GAP PF02145.15 EGC30055.1 - 4.1e-63 212.3 2.7 9.1e-63 211.2 2.7 1.6 1 0 0 1 1 1 1 Rap/ran-GAP RPEL PF02755.15 EGC30055.1 - 0.028 14.1 0.5 0.07 12.8 0.5 1.7 1 0 0 1 1 1 0 RPEL repeat MFS_1 PF07690.16 EGC30056.1 - 1.9e-32 112.6 54.1 4.5e-30 104.8 29.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC30056.1 - 7.6e-16 58.0 4.9 7.6e-16 58.0 4.9 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGC30056.1 - 0.075 12.3 9.0 0.021 14.1 4.0 2.3 2 1 1 3 3 3 0 Uncharacterised MFS-type transporter YbfB C12orf66_like PF09404.10 EGC30057.1 - 2.7e-44 151.7 9.2 1.8e-41 142.4 5.8 2.1 2 0 0 2 2 2 2 KICSTOR complex C12orf66 like RPM2 PF08579.11 EGC30057.1 - 0.006 17.0 0.6 0.006 17.0 0.6 2.0 2 0 0 2 2 2 1 Mitochondrial ribonuclease P subunit (RPM2) FtsH_ext PF06480.15 EGC30057.1 - 0.057 13.8 3.6 0.22 11.9 3.6 2.1 1 0 0 1 1 1 0 FtsH Extracellular DUF4689 PF15755.5 EGC30057.1 - 0.11 12.1 1.6 0.17 11.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4689) Actin PF00022.19 EGC30058.1 - 1.6e-147 491.4 0.0 5.3e-147 489.7 0.0 1.7 1 1 0 1 1 1 1 Actin Amino_oxidase PF01593.24 EGC30059.1 - 1.4e-46 159.8 0.0 8.6e-46 157.1 0.0 1.8 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC30059.1 - 1.3e-12 47.8 0.1 3e-12 46.6 0.0 1.7 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGC30059.1 - 0.00057 19.1 0.1 0.0008 18.6 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain Thi4 PF01946.17 EGC30059.1 - 0.001 18.3 0.2 0.0022 17.3 0.1 1.5 2 0 0 2 2 2 1 Thi4 family FAD_oxidored PF12831.7 EGC30059.1 - 0.0057 16.1 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGC30059.1 - 0.0074 15.6 0.1 0.012 14.8 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGC30059.1 - 0.0094 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 HI0933-like protein DAO PF01266.24 EGC30059.1 - 0.018 14.7 0.1 0.028 14.0 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGC30059.1 - 0.022 14.0 0.0 0.041 13.1 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC30059.1 - 0.051 14.1 0.1 0.12 12.9 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGC30059.1 - 0.071 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GIDA PF01134.22 EGC30059.1 - 0.17 11.0 0.1 0.34 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A N6_N4_Mtase PF01555.18 EGC30060.1 - 1.3e-05 25.1 0.9 0.00062 19.5 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Amidohydro_3 PF07969.11 EGC30061.1 - 9.4e-19 68.2 0.1 8.4e-11 42.0 0.0 2.5 2 1 0 2 2 2 2 Amidohydrolase family Amidohydro_1 PF01979.20 EGC30061.1 - 2.9e-18 66.3 0.3 3.7e-14 52.8 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family Kdo PF06293.14 EGC30062.1 - 0.00064 19.1 0.3 0.0018 17.7 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_int_SAM_2 PF12834.7 EGC30062.1 - 0.059 14.1 0.4 0.14 12.8 0.1 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal Trm5_N PF18093.1 EGC30062.1 - 0.11 12.4 0.9 15 5.6 0.1 3.1 3 0 0 3 3 3 0 tRNA methyltransferase 5 N-terminal domain Caskin-Pro-rich PF16907.5 EGC30064.1 - 0.025 15.1 1.0 0.029 14.9 1.0 1.2 1 1 0 1 1 1 0 Proline rich region of Caskin proteins Oxidored_FMN PF00724.20 EGC30065.1 - 5.8e-67 226.4 0.0 6.8e-67 226.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGC30065.1 - 0.0035 16.5 0.0 0.012 14.7 0.0 1.7 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) AAR2 PF05282.11 EGC30066.1 - 0.045 13.2 4.8 0.055 12.9 4.8 1.4 1 0 0 1 1 1 0 AAR2 protein SR-25 PF10500.9 EGC30066.1 - 0.14 11.7 8.1 0.21 11.2 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.13 EGC30066.1 - 0.64 8.9 7.2 0.89 8.4 7.2 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF4637 PF15470.6 EGC30066.1 - 1.9 8.2 5.8 4 7.1 5.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) RNA_polI_A14 PF08203.11 EGC30066.1 - 7.9 7.3 11.7 2 9.2 3.8 3.2 1 1 2 3 3 3 0 Yeast RNA polymerase I subunit RPA14 ALMT PF11744.8 EGC30066.1 - 9.2 5.0 14.2 15 4.3 14.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Pox_Ag35 PF03286.14 EGC30066.1 - 9.8 5.9 16.6 0.46 10.2 10.9 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC2_membrane_3 PF12698.7 EGC30067.1 - 1.1e-52 179.3 62.1 1.1e-28 100.4 20.5 2.6 3 0 0 3 3 3 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGC30067.1 - 9e-52 175.2 0.0 2.6e-26 92.8 0.1 2.9 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC30067.1 - 2.3e-19 70.3 0.8 4.2e-07 30.1 0.0 4.8 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC30067.1 - 2.1e-07 30.6 0.0 1 8.8 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC30067.1 - 0.00035 20.2 1.0 0.12 12.1 0.0 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.22 EGC30067.1 - 0.00047 19.9 0.3 0.43 10.2 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain RsgA_GTPase PF03193.16 EGC30067.1 - 0.0099 15.8 0.2 0.62 9.9 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_30 PF13604.6 EGC30067.1 - 0.073 12.8 0.4 5 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_27 PF13514.6 EGC30067.1 - 0.079 12.5 0.2 4 7.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGC30067.1 - 0.29 11.6 16.9 0.28 11.6 0.1 3.9 4 0 0 4 4 4 0 AAA domain ABC2_membrane PF01061.24 EGC30067.1 - 0.43 10.0 41.3 0.011 15.2 17.7 4.0 4 0 0 4 4 4 0 ABC-2 type transporter DUF4834 PF16118.5 EGC30068.1 - 0.0028 18.6 12.1 0.092 13.7 3.4 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4834) DUF2464 PF10240.9 EGC30068.1 - 0.0055 16.3 8.7 0.075 12.6 4.3 2.2 2 0 0 2 2 2 1 Multivesicular body subunit 12 EPL1 PF10513.9 EGC30068.1 - 0.015 15.7 18.4 0.47 10.8 6.9 2.5 2 0 0 2 2 2 0 Enhancer of polycomb-like MID_MedPIWI PF18296.1 EGC30068.1 - 0.018 14.9 12.7 0.7 9.6 0.2 2.2 2 0 0 2 2 2 0 MID domain of medPIWI Gti1_Pac2 PF09729.9 EGC30068.1 - 0.029 14.5 12.9 0.86 9.7 0.1 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Secretin_N_2 PF07655.13 EGC30068.1 - 0.036 14.6 47.3 0.98 10.0 20.3 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CSG2 PF16965.5 EGC30068.1 - 0.13 11.2 12.2 0.88 8.5 1.8 2.2 2 0 0 2 2 2 0 Ceramide synthase regulator DAG_kinase_N PF14513.6 EGC30068.1 - 0.14 12.3 7.2 2.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus DUF4484 PF14831.6 EGC30068.1 - 0.2 11.7 1.9 12 5.8 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) Folate_carrier PF01770.18 EGC30068.1 - 0.23 10.1 5.1 2.9 6.5 0.1 2.2 2 0 0 2 2 2 0 Reduced folate carrier PRC2_HTH_1 PF18118.1 EGC30068.1 - 1.1 10.1 11.1 3.5 8.5 1.1 2.9 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain POX PF07526.11 EGC30068.1 - 1.2 9.7 8.2 13 6.4 2.8 2.4 2 0 0 2 2 2 0 Associated with HOX Pox_Ag35 PF03286.14 EGC30068.1 - 1.6 8.5 17.4 0.44 10.3 3.6 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Apc15p PF05841.11 EGC30068.1 - 2 9.2 33.7 1.9 9.3 7.2 2.4 2 0 0 2 2 2 0 Apc15p protein CENP-B_dimeris PF09026.10 EGC30068.1 - 2.1 8.8 10.5 9.7 6.7 0.7 3.2 3 0 0 3 3 3 0 Centromere protein B dimerisation domain EOS1 PF12326.8 EGC30068.1 - 2.6 7.9 7.7 9.5 6.1 4.3 2.3 2 0 0 2 2 2 0 N-glycosylation protein Corazonin PF17308.2 EGC30068.1 - 3.2 8.1 43.7 0.15 12.4 13.4 3.2 3 0 0 3 3 2 0 Pro-corazonin FAM60A PF15396.6 EGC30068.1 - 3.4 7.6 12.0 17 5.4 0.1 2.4 2 0 0 2 2 2 0 Protein Family FAM60A Rxt3 PF08642.10 EGC30068.1 - 4.4 8.1 7.8 23 5.8 2.4 2.4 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 Peroxin-13_N PF04088.13 EGC30068.1 - 5.6 7.2 9.9 8.5 6.6 0.4 2.9 3 0 0 3 3 3 0 Peroxin 13, N-terminal region Menin PF05053.13 EGC30068.1 - 9.1 4.5 24.6 0.33 9.3 7.1 2.2 2 0 0 2 2 2 0 Menin Tyrosinase PF00264.20 EGC30068.1 - 9.9 6.4 15.9 9.7 6.4 1.5 2.2 2 0 0 2 2 2 0 Common central domain of tyrosinase ABC2_membrane PF01061.24 EGC30069.1 - 6.8e-92 306.6 47.4 1.4e-49 168.4 25.5 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC30069.1 - 1.2e-51 174.8 2.7 1e-26 94.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter PDR_assoc PF08370.11 EGC30069.1 - 5.1e-10 39.0 1.1 2.2e-07 30.5 0.4 3.1 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_29 PF13555.6 EGC30069.1 - 9.2e-09 34.9 0.1 0.002 17.8 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC30069.1 - 2.2e-08 34.2 0.3 0.00079 19.4 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase Rad17 PF03215.15 EGC30069.1 - 1.2e-07 31.9 0.0 0.0084 16.0 0.0 2.8 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_16 PF13191.6 EGC30069.1 - 1.4e-07 32.1 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGC30069.1 - 1.4e-06 28.6 0.0 0.089 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ABC2_membrane_3 PF12698.7 EGC30069.1 - 4.2e-05 22.8 21.2 4.2e-05 22.8 21.2 4.1 3 1 1 4 4 3 2 ABC-2 family transporter protein AAA_25 PF13481.6 EGC30069.1 - 0.00013 21.6 0.0 0.076 12.6 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGC30069.1 - 0.00027 21.2 0.2 1 9.6 0.1 2.4 2 0 0 2 2 2 2 AAA domain AAA_33 PF13671.6 EGC30069.1 - 0.00027 21.1 0.0 0.18 12.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA PF00004.29 EGC30069.1 - 0.00029 21.3 0.1 0.23 11.9 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGC30069.1 - 0.00031 21.1 0.0 0.62 10.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.17 EGC30069.1 - 0.00036 20.3 0.0 0.21 11.3 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein MMR_HSR1 PF01926.23 EGC30069.1 - 0.00052 20.1 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGC30069.1 - 0.00072 19.5 12.1 0.1 12.4 0.0 5.1 4 1 2 6 6 5 1 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EGC30069.1 - 0.00076 19.4 0.3 0.4 10.6 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 EGC30069.1 - 0.0037 17.7 1.4 1.7 9.0 0.0 3.1 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EGC30069.1 - 0.0055 16.5 0.1 2.2 8.0 0.2 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC30069.1 - 0.0056 17.2 0.0 0.099 13.2 0.0 3.7 5 0 0 5 5 2 2 AAA domain AAA_7 PF12775.7 EGC30069.1 - 0.006 16.1 0.1 1 8.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing dynein motor region NTPase_1 PF03266.15 EGC30069.1 - 0.0095 15.9 1.3 0.7 9.8 0.0 3.0 3 0 0 3 3 2 1 NTPase Zeta_toxin PF06414.12 EGC30069.1 - 0.011 15.0 0.1 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_5 PF07728.14 EGC30069.1 - 0.014 15.4 1.0 2.4 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PDR_CDR PF06422.12 EGC30069.1 - 0.024 14.5 0.2 0.024 14.5 0.2 3.9 3 0 0 3 3 3 0 CDR ABC transporter MeaB PF03308.16 EGC30069.1 - 0.04 12.9 0.0 8.3 5.3 0.0 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Viral_helicase1 PF01443.18 EGC30069.1 - 0.064 13.0 0.0 0.4 10.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.6 EGC30069.1 - 0.077 13.5 0.1 0.077 13.5 0.1 4.1 3 1 1 4 4 3 0 AAA domain AAA_24 PF13479.6 EGC30069.1 - 0.1 12.3 0.4 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.25 EGC30069.1 - 0.16 11.6 0.0 5.2 6.7 0.0 2.5 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain Mg_chelatase PF01078.21 EGC30069.1 - 0.17 11.2 0.2 6.8 6.0 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGC30069.1 - 0.3 11.1 4.1 13 5.9 0.0 3.4 3 0 0 3 3 2 0 AAA domain Cytidylate_kin PF02224.18 EGC30069.1 - 0.55 9.9 4.6 0.7 9.6 0.1 2.9 3 0 0 3 3 2 0 Cytidylate kinase ATPase_2 PF01637.18 EGC30069.1 - 1.8 8.4 7.6 0.82 9.5 0.0 2.8 3 0 0 3 3 2 0 ATPase domain predominantly from Archaea Msap1 PF17077.5 EGC30070.1 - 0.036 13.2 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 Mitotic spindle associated protein SHE1 TCR PF03638.15 EGC30070.1 - 0.25 11.7 27.3 0.46 10.8 27.3 1.5 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain VESA1_N PF12785.7 EGC30070.1 - 0.85 8.5 9.9 1.3 8.0 9.9 1.3 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 preSET_CXC PF18264.1 EGC30070.1 - 6 7.4 20.0 26 5.4 20.0 2.0 1 1 0 1 1 1 0 CXC domain UCH PF00443.29 EGC30071.1 - 2.4e-39 135.4 1.8 2.4e-39 135.4 1.8 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGC30071.1 - 2.6e-14 53.3 6.3 4.7e-14 52.4 6.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein zf-UBP_var PF17807.1 EGC30071.1 - 0.0096 15.7 4.1 0.022 14.5 4.1 1.6 1 0 0 1 1 1 1 Variant UBP zinc finger UCH_1 PF13423.6 EGC30071.1 - 0.24 11.0 8.2 0.89 9.1 3.8 3.3 2 1 0 2 2 2 0 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.32 EGC30072.1 - 1.2e-10 41.8 25.0 0.015 16.1 0.1 6.8 6 0 0 6 6 6 5 WD domain, G-beta repeat C1_2 PF03107.16 EGC30072.1 - 0.0047 17.2 6.3 0.0047 17.2 6.3 2.1 2 0 0 2 2 2 1 C1 domain ANAPC4_WD40 PF12894.7 EGC30072.1 - 0.011 16.0 1.8 1.3 9.4 0.1 3.9 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain C1_1 PF00130.22 EGC30072.1 - 0.23 11.3 9.6 0.6 10.0 9.6 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.6 EGC30072.1 - 0.25 11.3 7.0 0.65 10.0 7.0 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 PHD PF00628.29 EGC30072.1 - 0.34 10.8 9.3 1 9.3 9.3 1.8 1 0 0 1 1 1 0 PHD-finger CLU PF13236.6 EGC30073.1 - 3.3e-61 206.9 0.0 8.8e-61 205.5 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria SH2 PF00017.24 EGC30073.1 - 3.7e-09 36.6 0.0 1.3e-08 34.9 0.0 2.0 1 0 0 1 1 1 1 SH2 domain eIF3_p135 PF12807.7 EGC30073.1 - 1.3e-08 35.0 0.1 1.3e-08 35.0 0.1 3.5 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 dNK PF01712.19 EGC30074.1 - 2e-43 148.7 0.0 2.7e-43 148.2 0.0 1.3 1 1 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.17 EGC30074.1 - 3.3e-06 26.9 0.1 7.3e-06 25.8 0.0 1.7 2 0 0 2 2 2 1 Thymidylate kinase TsaE PF02367.17 EGC30074.1 - 0.0029 17.6 0.0 0.0054 16.7 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGC30074.1 - 0.0082 16.4 0.0 0.012 15.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGC30074.1 - 0.012 15.8 0.0 0.025 14.7 0.0 1.5 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC30074.1 - 0.03 14.9 0.1 0.1 13.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain PPK2 PF03976.14 EGC30074.1 - 0.061 12.8 0.0 0.26 10.8 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) RGS PF00615.19 EGC30075.1 - 1.4e-15 57.6 0.0 2.9e-15 56.6 0.0 1.5 1 1 0 1 1 1 1 Regulator of G protein signaling domain SOG2 PF10428.9 EGC30075.1 - 0.0026 17.0 0.6 0.003 16.8 0.6 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein Secretin_N_2 PF07655.13 EGC30075.1 - 1.5 9.4 10.0 0.68 10.5 6.5 1.9 2 0 0 2 2 2 0 Secretin N-terminal domain dCMP_cyt_deam_1 PF00383.23 EGC30077.1 - 6e-17 61.4 0.8 9.7e-17 60.7 0.8 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGC30077.1 - 2.6e-11 43.4 1.3 3.7e-11 42.9 1.3 1.3 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGC30077.1 - 0.022 14.8 0.5 4.1 7.5 0.0 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase RCC1_2 PF13540.6 EGC30077.1 - 0.15 11.9 0.3 0.44 10.4 0.0 1.9 2 0 0 2 2 2 0 Regulator of chromosome condensation (RCC1) repeat TMEM144 PF07857.12 EGC30078.1 - 1.8e-77 260.6 21.2 2e-77 260.4 21.2 1.0 1 0 0 1 1 1 1 Transmembrane family, TMEM144 of transporters Sugar_transport PF06800.12 EGC30078.1 - 1.4e-06 27.8 19.5 7e-06 25.6 6.5 2.7 2 2 0 2 2 2 2 Sugar transport protein DMT_YdcZ PF04657.13 EGC30078.1 - 0.00074 19.8 12.1 0.00074 19.8 12.1 2.5 2 0 0 2 2 2 1 Putative inner membrane exporter, YdcZ RRM_1 PF00076.22 EGC30079.1 - 8.3e-19 67.2 0.1 9.5e-19 67.0 0.1 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC30079.1 - 0.0025 17.9 0.0 0.0047 17.0 0.0 1.5 1 1 0 1 1 1 1 RNA recognition motif CSTF2_hinge PF14327.6 EGC30080.1 - 1.9e-14 53.9 19.2 2.7e-13 50.2 19.2 2.6 1 1 0 1 1 1 1 Hinge domain of cleavage stimulation factor subunit 2 Pentapeptide_2 PF01469.18 EGC30080.1 - 0.0064 16.3 20.5 0.0064 16.3 20.5 5.6 3 2 3 6 6 6 4 Pentapeptide repeats (8 copies) TFIIA PF03153.13 EGC30081.1 - 0.014 15.4 10.6 0.017 15.1 10.6 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2672 PF10878.8 EGC30081.1 - 0.016 15.1 0.3 0.016 15.1 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) Striatin PF08232.12 EGC30081.1 - 0.045 14.3 9.9 0.064 13.8 9.9 1.2 1 0 0 1 1 1 0 Striatin family MAS20 PF02064.15 EGC30081.1 - 0.27 11.4 9.0 0.75 9.9 5.4 3.0 3 0 0 3 3 3 0 MAS20 protein import receptor RP-C_C PF11800.8 EGC30081.1 - 1.1 9.3 6.6 1.6 8.8 6.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF1664 PF07889.12 EGC30081.1 - 1.8 8.6 8.5 1.2 9.2 3.8 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) Presenilin PF01080.17 EGC30081.1 - 2.1 7.0 7.2 2.9 6.5 7.2 1.2 1 0 0 1 1 1 0 Presenilin WCCH PF03716.14 EGC30083.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif Lyase_1 PF00206.20 EGC30085.1 - 1.3e-117 392.7 0.0 1.9e-117 392.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.9 EGC30085.1 - 2.4e-26 91.9 0.1 1.1e-25 89.8 0.0 2.2 2 0 0 2 2 2 1 Fumarase C C-terminus SBP_bac_3 PF00497.20 EGC30085.1 - 0.00091 18.7 0.0 0.0023 17.4 0.0 1.6 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 3 G-alpha PF00503.20 EGC30085.1 - 0.062 12.4 0.0 0.2 10.8 0.0 1.7 2 0 0 2 2 2 0 G-protein alpha subunit HsbA PF12296.8 EGC30085.1 - 0.12 12.8 0.8 0.69 10.4 0.2 2.5 2 0 0 2 2 2 0 Hydrophobic surface binding protein A Pept_tRNA_hydro PF01195.19 EGC30086.1 - 1.6e-45 155.2 0.2 1.8e-45 154.9 0.2 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SRP54_N PF02881.19 EGC30086.1 - 0.026 14.7 0.9 0.22 11.8 0.3 2.2 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain WD40 PF00400.32 EGC30088.1 - 1.8e-66 218.5 16.4 2e-11 44.2 0.2 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30088.1 - 7.4e-28 96.7 0.9 1.2e-05 25.5 0.0 6.2 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC30088.1 - 3.6e-15 56.3 1.1 5.9e-06 26.3 0.0 4.0 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGC30088.1 - 2.3e-12 46.4 0.5 0.0098 14.6 0.0 4.4 1 1 3 4 4 4 4 Nucleoporin Nup120/160 WD40_like PF17005.5 EGC30088.1 - 4.3e-09 36.1 0.1 3.5e-07 29.8 0.1 3.0 1 1 1 2 2 2 1 WD40-like domain Ge1_WD40 PF16529.5 EGC30088.1 - 1.8e-08 33.7 2.2 0.016 14.2 0.0 4.7 1 1 3 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGC30088.1 - 6.4e-05 21.6 0.1 0.0014 17.3 0.1 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain Nucleoporin_N PF08801.11 EGC30088.1 - 8.4e-05 21.5 7.6 0.076 11.7 1.2 4.4 1 1 2 4 4 4 2 Nup133 N terminal like PALB2_WD40 PF16756.5 EGC30088.1 - 0.00031 19.8 0.2 0.1 11.5 0.0 2.9 1 1 1 3 3 3 2 Partner and localizer of BRCA2 WD40 domain Utp8 PF10395.9 EGC30088.1 - 0.0074 14.8 0.0 0.012 14.2 0.0 1.3 1 1 0 1 1 1 1 Utp8 family Nbas_N PF15492.6 EGC30088.1 - 0.016 14.5 1.3 11 5.3 0.0 3.8 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.6 EGC30088.1 - 0.018 15.5 0.6 3.8 8.1 0.2 3.0 3 0 0 3 3 3 0 PQQ-like domain DUF5046 PF16465.5 EGC30088.1 - 0.026 14.0 0.0 0.051 13.0 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5046) PD40 PF07676.12 EGC30088.1 - 0.028 14.4 3.8 0.85 9.6 0.1 3.9 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat PQQ_2 PF13360.6 EGC30088.1 - 0.038 13.6 0.3 0.59 9.7 0.1 2.4 1 1 2 3 3 3 0 PQQ-like domain PQQ PF01011.21 EGC30088.1 - 0.044 13.7 0.0 5.3 7.2 0.1 3.1 2 0 0 2 2 2 0 PQQ enzyme repeat Lactonase PF10282.9 EGC30088.1 - 0.071 12.3 0.1 4 6.6 0.0 2.8 1 1 1 3 3 3 0 Lactonase, 7-bladed beta-propeller SecE PF00584.20 EGC30089.1 - 2.7e-16 59.2 0.1 3e-16 59.1 0.1 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex CbtB PF09489.10 EGC30089.1 - 0.045 13.9 0.1 0.058 13.5 0.1 1.2 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtB) UBA PF00627.31 EGC30090.1 - 9.3e-12 44.6 0.1 3e-11 43.0 0.0 1.9 2 0 0 2 2 2 1 UBA/TS-N domain UBA_4 PF14555.6 EGC30090.1 - 0.00053 19.7 0.3 0.0014 18.4 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain UBA_3 PF09288.10 EGC30090.1 - 0.00076 19.2 0.0 0.0014 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain DUF1421 PF07223.11 EGC30090.1 - 0.0044 16.8 0.0 0.01 15.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain (DUF1421) LSM PF01423.22 EGC30091.1 - 4e-15 55.2 0.1 5.9e-15 54.7 0.1 1.3 1 0 0 1 1 1 1 LSM domain HMG_CoA_synt_C PF08540.10 EGC30092.1 - 1.8e-91 306.6 7.2 2.4e-91 306.2 7.2 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.17 EGC30092.1 - 6.3e-90 299.7 0.1 9.5e-90 299.1 0.1 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal IF3_C PF00707.22 EGC30093.1 - 4.6e-07 29.7 0.3 2.2e-06 27.6 0.3 2.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Rft-1 PF04506.13 EGC30094.1 - 5.3e-91 305.9 41.8 9.4e-91 305.1 41.8 1.4 1 1 0 1 1 1 1 Rft protein Imm26 PF15428.6 EGC30094.1 - 0.00032 20.9 0.3 0.00096 19.4 0.3 1.8 1 0 0 1 1 1 1 Immunity protein 26 Gemini_mov PF01708.16 EGC30094.1 - 0.025 14.3 0.3 1.9 8.3 1.2 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein PPC PF04151.15 EGC30094.1 - 2.4 9.3 8.6 1.8 9.7 0.5 2.8 2 0 0 2 2 2 0 Bacterial pre-peptidase C-terminal domain Sas10_Utp3 PF04000.15 EGC30095.1 - 1.4e-14 54.4 1.0 1.7e-14 54.2 0.3 1.5 1 1 1 2 2 2 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.8 EGC30095.1 - 0.0048 15.8 0.2 0.0056 15.5 0.2 1.1 1 0 0 1 1 1 1 Fungal specific transcription factor domain RIBIOP_C PF04950.12 EGC30096.1 - 9.4e-90 301.0 0.3 9.4e-90 301.0 0.3 2.7 3 0 0 3 3 1 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGC30096.1 - 5.9e-30 103.2 0.0 5.9e-30 103.2 0.0 3.7 4 0 0 4 4 3 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.27 EGC30096.1 - 3e-07 30.2 1.6 3.6e-05 23.4 0.0 3.1 2 1 1 3 3 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGC30096.1 - 0.00021 21.1 0.1 0.00075 19.3 0.1 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA PF00004.29 EGC30096.1 - 0.00031 21.2 0.0 0.00082 19.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.23 EGC30096.1 - 0.00049 20.2 0.5 0.014 15.5 0.1 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGC30096.1 - 0.00088 19.6 0.0 0.0027 18.0 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGC30096.1 - 0.0014 18.7 0.9 0.0057 16.7 0.0 2.6 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.6 EGC30096.1 - 0.0041 17.3 0.0 0.014 15.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain FeoB_N PF02421.18 EGC30096.1 - 0.0072 15.9 0.1 0.31 10.6 0.0 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGC30096.1 - 0.014 15.8 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EGC30096.1 - 0.033 14.6 0.0 0.1 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Crp PF00325.20 EGC30096.1 - 0.14 11.9 0.1 0.45 10.2 0.1 1.9 1 0 0 1 1 1 0 Bacterial regulatory proteins, crp family ABC_tran PF00005.27 EGC30096.1 - 0.3 11.6 0.0 0.3 11.6 0.0 3.3 4 1 0 4 4 3 0 ABC transporter Pantoate_ligase PF02569.15 EGC30096.1 - 1.8 7.7 7.6 3.4 6.8 7.6 1.4 1 0 0 1 1 1 0 Pantoate-beta-alanine ligase Actin PF00022.19 EGC30097.1 - 3.7e-26 91.7 8.5 4.3e-12 45.4 0.0 4.8 3 1 2 5 5 5 4 Actin FtsA PF14450.6 EGC30097.1 - 0.0077 16.6 0.5 0.68 10.4 0.0 2.9 2 0 0 2 2 2 1 Cell division protein FtsA KfrA_N PF11740.8 EGC30097.1 - 0.15 12.8 10.5 0.32 11.7 10.5 1.5 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term UQ_con PF00179.26 EGC30098.1 - 5e-45 152.6 0.1 5.7e-45 152.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGC30098.1 - 0.0043 16.7 0.0 0.0086 15.8 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B GTP_cyclohydroI PF01227.22 EGC30099.1 - 1e-74 249.8 0.7 1.3e-74 249.5 0.7 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.6 EGC30099.1 - 0.0016 18.5 0.0 0.0043 17.2 0.0 1.7 2 0 0 2 2 2 1 QueF-like protein MIF PF01187.18 EGC30099.1 - 0.05 13.9 0.1 0.089 13.1 0.1 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) DNase_II PF03265.15 EGC30100.1 - 4.9e-29 101.6 22.6 9e-24 84.3 11.8 2.5 2 1 1 3 3 3 2 Deoxyribonuclease II DUF3439 PF11921.8 EGC30102.1 - 0.0093 15.9 5.0 0.021 14.8 5.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC30102.1 - 0.14 12.2 9.7 0.24 11.4 9.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CobT PF06213.12 EGC30105.1 - 0.19 11.1 15.5 0.28 10.6 15.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Cytomega_UL84 PF06284.11 EGC30105.1 - 1.4 7.3 8.4 1.9 6.9 8.4 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FlaC_arch PF05377.11 EGC30105.1 - 3.9 7.9 12.0 0.08 13.3 3.9 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) MMM1 PF10296.9 EGC30107.1 - 2.4e-12 46.6 0.5 1.9e-09 37.0 0.2 2.6 2 1 1 3 3 3 2 Maintenance of mitochondrial morphology protein 1 PH PF00169.29 EGC30107.1 - 1.9e-06 28.3 0.2 5.9e-06 26.7 0.2 1.8 1 0 0 1 1 1 1 PH domain Mistic PF11458.8 EGC30107.1 - 0.12 12.3 0.6 13 5.8 0.0 3.2 3 0 0 3 3 3 0 Membrane-integrating protein Mistic Arm PF00514.23 EGC30108.1 - 9.4e-88 285.9 17.1 9.4e-12 44.5 0.0 9.2 9 0 0 9 9 9 9 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGC30108.1 - 4e-22 78.3 1.7 3.3e-08 33.9 0.0 6.2 6 2 2 8 8 6 3 HEAT-like repeat IBB PF01749.20 EGC30108.1 - 7.6e-20 71.1 5.1 1.7e-19 70.0 5.1 1.6 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 EGC30108.1 - 6.7e-19 68.1 0.1 3.5e-05 24.1 0.0 5.3 1 1 5 6 6 6 6 HEAT repeats Arm_3 PF16186.5 EGC30108.1 - 2.3e-12 46.2 0.4 5.1e-12 45.2 0.4 1.6 1 0 0 1 1 1 1 Atypical Arm repeat HEAT PF02985.22 EGC30108.1 - 6.6e-12 44.6 4.9 0.015 15.5 0.0 8.3 9 1 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.20 EGC30108.1 - 6.4e-08 31.6 0.4 1.6e-05 23.7 0.1 3.0 1 1 1 2 2 2 2 Adaptin N terminal region V-ATPase_H_C PF11698.8 EGC30108.1 - 1.2e-05 25.4 0.3 0.79 9.9 0.0 4.4 4 1 1 5 5 5 3 V-ATPase subunit H RICTOR_V PF14668.6 EGC30108.1 - 3.4e-05 24.0 0.1 0.5 10.6 0.0 4.7 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_PBS PF03130.16 EGC30108.1 - 4.8e-05 23.6 0.3 0.088 13.5 0.0 5.0 6 0 0 6 6 5 1 PBS lyase HEAT-like repeat Mo25 PF08569.11 EGC30108.1 - 0.0037 16.7 0.0 0.38 10.1 0.0 2.7 1 1 1 2 2 2 1 Mo25-like DUF1955 PF09205.10 EGC30108.1 - 0.11 12.3 2.1 2.8 7.6 0.0 3.9 4 0 0 4 4 4 0 Domain of unknown function (DUF1955) Atx10homo_assoc PF09759.9 EGC30108.1 - 0.17 11.9 1.2 17 5.5 0.0 3.8 3 1 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EGC30108.1 - 0.64 10.0 2.9 6 6.8 0.1 3.7 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) Snurportin1 PF11538.8 EGC30108.1 - 5.7 7.2 7.8 10 6.4 7.8 1.4 1 0 0 1 1 1 0 Snurportin1 Ank_4 PF13637.6 EGC30109.1 - 0.029 15.0 0.0 0.081 13.5 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC30109.1 - 0.029 15.0 0.0 0.074 13.6 0.0 1.7 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ribosomal_S8 PF00410.19 EGC30109.1 - 0.5 10.3 2.4 2.9 7.9 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein S8 Ribonuclease_3 PF00636.26 EGC30110.1 - 0.00019 22.0 4.3 0.0002 21.9 0.1 2.8 2 2 0 2 2 2 1 Ribonuclease III domain Exonuc_VII_L PF02601.15 EGC30110.1 - 0.15 11.6 6.3 0.22 11.1 6.3 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulf_transp PF04143.14 EGC30111.1 - 1.2e-43 149.8 9.1 1.9e-43 149.2 9.1 1.3 1 0 0 1 1 1 1 Sulphur transport DUF5453 PF17534.2 EGC30111.1 - 0.00046 20.2 2.2 0.00046 20.2 2.2 1.8 2 0 0 2 2 2 1 Family of unknown function (DUF5453) SH2_2 PF14633.6 EGC30112.1 - 1e-55 188.5 0.1 2.2e-55 187.4 0.1 1.5 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.6 EGC30112.1 - 6.1e-21 74.7 0.3 1.3e-20 73.7 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.6 EGC30112.1 - 2e-19 69.9 0.0 4.3e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 HTH_44 PF14641.6 EGC30112.1 - 5.6e-14 52.6 2.7 1.6e-13 51.1 2.7 1.7 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 HHH_9 PF17674.1 EGC30112.1 - 0.0004 21.2 0.8 0.0004 21.2 0.8 2.5 2 0 0 2 2 2 1 HHH domain HHH_3 PF12836.7 EGC30112.1 - 0.13 12.5 0.0 0.29 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pyr_redox_2 PF07992.14 EGC30113.1 - 1.6e-61 208.1 0.5 2.9e-61 207.3 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGC30113.1 - 3.4e-33 114.2 1.1 7.4e-33 113.1 0.8 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGC30113.1 - 3.9e-18 65.8 0.2 1.1e-17 64.3 0.2 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC30113.1 - 2.8e-15 56.4 0.6 1.6e-14 53.9 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGC30113.1 - 0.0014 17.9 0.0 0.0033 16.6 0.0 1.5 1 1 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGC30113.1 - 0.02 13.6 0.7 2.3 6.8 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein DAO PF01266.24 EGC30113.1 - 0.042 13.4 3.1 0.3 10.6 0.0 2.4 2 0 0 2 2 2 0 FAD dependent oxidoreductase zf-Tim10_DDP PF02953.15 EGC30114.1 - 2.3e-10 40.0 5.1 2.3e-10 40.0 5.1 1.6 1 1 1 2 2 2 1 Tim10/DDP family zinc finger NCD3G PF07562.14 EGC30114.1 - 0.055 13.4 0.4 0.086 12.8 0.4 1.3 1 0 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR Pkinase PF00069.25 EGC30115.1 - 2.6e-77 259.7 0.0 3e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30115.1 - 1.2e-32 113.2 0.0 1.7e-32 112.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC30115.1 - 3.1e-06 26.4 0.0 8.5e-05 21.6 0.0 2.0 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGC30115.1 - 0.00019 21.5 0.1 0.0023 17.9 0.1 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC30115.1 - 0.0033 16.5 0.0 0.0058 15.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.6 EGC30115.1 - 0.0057 16.0 0.1 0.033 13.5 0.1 2.2 2 1 0 2 2 2 1 Kinase-like Ion_trans PF00520.31 EGC30120.1 - 0.0049 16.1 0.1 0.0049 16.1 0.1 1.1 1 0 0 1 1 1 1 Ion transport protein DUF3430 PF11912.8 EGC30120.1 - 1 9.4 11.1 1.5 8.8 11.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) I_LWEQ PF01608.17 EGC30122.1 - 0.0063 16.8 8.6 1.1 9.5 0.8 3.4 2 1 0 2 2 2 2 I/LWEQ domain TerB PF05099.13 EGC30122.1 - 0.023 14.6 1.2 0.023 14.6 1.2 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TerB Med20 PF08612.11 EGC30123.1 - 0.029 13.7 0.2 0.6 9.4 0.1 2.3 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex YwpF PF14183.6 EGC30123.1 - 0.057 13.4 0.5 14 5.6 0.1 2.4 2 0 0 2 2 2 0 YwpF-like protein DUF4364 PF14277.6 EGC30123.1 - 0.26 11.0 2.0 14 5.3 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) Brr6_like_C_C PF10104.9 EGC30124.1 - 8.2e-10 38.6 0.8 8.2e-10 38.6 0.8 5.2 5 1 1 6 6 6 2 Di-sulfide bridge nucleocytoplasmic transport domain DUF898 PF05987.13 EGC30124.1 - 3e-05 23.2 7.3 0.0043 16.1 0.5 2.1 2 0 0 2 2 2 2 Bacterial protein of unknown function (DUF898) 7TM_GPCR_Srw PF10324.9 EGC30124.1 - 8.2e-05 22.0 20.8 0.011 15.0 3.5 2.6 2 1 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw Virul_fac_BrkB PF03631.15 EGC30124.1 - 0.0007 19.3 14.3 0.013 15.2 7.8 3.0 2 1 0 2 2 2 2 Virulence factor BrkB Cyt_bd_oxida_II PF02322.15 EGC30124.1 - 0.014 14.7 0.9 0.014 14.7 0.9 3.1 2 2 1 3 3 3 0 Cytochrome bd terminal oxidase subunit II DUF4271 PF14093.6 EGC30124.1 - 1.2 9.1 33.4 0.14 12.0 8.7 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4271) SARAF PF06682.12 EGC30124.1 - 1.7 8.2 4.0 6.6 6.3 0.3 3.0 2 2 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis DUF2615 PF11027.8 EGC30124.1 - 1.8 8.7 9.4 0.42 10.8 0.4 3.9 4 2 2 6 6 6 0 Protein of unknown function (DUF2615) DUF3784 PF12650.7 EGC30124.1 - 2.6 8.3 34.2 2.9 8.2 4.9 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF3784) Shisa PF13908.6 EGC30124.1 - 4.6 7.4 8.2 7 6.9 0.0 3.3 2 2 1 3 3 3 0 Wnt and FGF inhibitory regulator zf-C3HC4_3 PF13920.6 EGC30125.1 - 1.2e-07 31.5 4.3 1.7e-07 31.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30125.1 - 6.5e-06 25.9 11.4 6.2e-05 22.8 11.2 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30125.1 - 7.3e-06 25.7 5.0 7.3e-06 25.7 5.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC30125.1 - 4.2e-05 23.4 9.1 9.2e-05 22.3 9.1 1.6 1 1 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC30125.1 - 0.00011 21.9 7.4 0.00022 21.0 7.4 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC30125.1 - 0.00026 21.2 9.0 0.00073 19.8 9.0 1.7 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGC30125.1 - 0.00028 21.1 4.4 0.00053 20.2 4.4 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC30125.1 - 0.004 17.0 3.5 0.0085 16.0 3.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein DUF2985 PF11204.8 EGC30125.1 - 0.0084 16.3 0.7 0.012 15.8 0.1 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF2985) Adeno_knob PF00541.17 EGC30125.1 - 0.0089 15.8 0.8 0.012 15.3 0.8 1.1 1 0 0 1 1 1 1 Adenoviral fibre protein (knob domain) zf-RING_UBOX PF13445.6 EGC30125.1 - 0.016 15.2 2.9 0.016 15.2 2.9 3.4 1 1 2 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC30125.1 - 0.02 15.0 5.7 0.02 15.0 5.7 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC30125.1 - 0.084 12.7 6.9 0.15 11.9 6.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC30125.1 - 0.13 12.4 3.6 0.25 11.5 3.6 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 OAD_gamma PF04277.13 EGC30125.1 - 0.14 12.8 0.6 0.87 10.2 0.0 2.1 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DZR PF12773.7 EGC30125.1 - 0.22 11.6 3.9 0.39 10.8 3.9 1.4 1 0 0 1 1 1 0 Double zinc ribbon Coleoptericin PF06286.11 EGC30125.1 - 0.27 11.3 2.3 0.87 9.7 2.3 1.8 1 1 0 1 1 1 0 Coleoptericin WD40 PF00400.32 EGC30127.1 - 8.3e-44 146.7 13.3 4.1e-10 40.1 0.9 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30127.1 - 3.2e-09 37.0 1.3 0.078 13.3 0.1 5.2 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGC30127.1 - 0.00018 20.4 0.2 0.64 8.7 0.0 3.7 2 1 3 5 5 5 4 Nup133 N terminal like WD40_like PF17005.5 EGC30127.1 - 0.0004 19.8 0.0 1.8 7.8 0.0 3.1 1 1 2 3 3 3 2 WD40-like domain Alfin PF12165.8 EGC30127.1 - 0.062 13.0 0.2 0.27 10.9 0.1 2.2 2 0 0 2 2 2 0 Alfin Rsm22 PF09243.10 EGC30128.1 - 2.1e-72 243.7 0.0 4.5e-72 242.6 0.0 1.6 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.6 EGC30128.1 - 6.3e-07 29.4 0.0 7.2e-06 25.9 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC30128.1 - 3.2e-05 24.5 0.0 0.0072 16.9 0.0 3.4 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30128.1 - 0.00058 20.5 0.0 0.019 15.7 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC30128.1 - 0.00098 18.5 0.0 0.0028 17.0 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ATP-synt_A PF00119.20 EGC30129.1 - 0.04 13.9 0.0 0.04 13.9 0.0 1.1 1 0 0 1 1 1 0 ATP synthase A chain Macoilin PF09726.9 EGC30130.1 - 0.034 12.7 13.5 0.038 12.5 13.5 1.0 1 0 0 1 1 1 0 Macoilin family UCH PF00443.29 EGC30134.1 - 8.8e-15 54.9 22.6 8.8e-15 54.9 22.6 5.2 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Pro-MCH PF05824.12 EGC30134.1 - 1.4 8.9 6.1 1.3 9.0 0.4 2.9 2 0 0 2 2 2 0 Pro-melanin-concentrating hormone (Pro-MCH) LRR_6 PF13516.6 EGC30135.1 - 4.3e-33 110.5 66.1 0.00036 20.4 0.1 16.8 18 0 0 18 18 18 11 Leucine Rich repeat LRR_4 PF12799.7 EGC30135.1 - 0.00016 22.0 59.1 0.086 13.3 0.7 9.7 7 2 5 12 12 12 9 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGC30135.1 - 0.058 13.3 0.1 0.15 11.9 0.1 1.7 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.33 EGC30135.1 - 0.092 13.3 34.2 24 6.0 0.1 11.9 14 0 0 14 14 14 0 Leucine Rich Repeat SpoU_sub_bind PF08032.12 EGC30135.1 - 0.14 12.5 0.1 13 6.2 0.0 3.6 4 0 0 4 4 4 0 RNA 2'-O ribose methyltransferase substrate binding YusW PF14039.6 EGC30135.1 - 0.28 11.7 8.7 14 6.3 0.1 4.4 3 1 1 4 4 4 0 YusW-like protein FNIP PF05725.12 EGC30136.1 - 3e-107 350.6 32.8 1.1e-17 63.9 1.3 8.1 4 1 3 9 9 9 9 FNIP Repeat SSURE PF11966.8 EGC30136.1 - 0.018 14.8 7.8 12 5.7 0.0 6.8 3 2 3 8 8 8 0 Fibronectin-binding repeat LRR_5 PF13306.6 EGC30136.1 - 0.24 11.4 1.9 9.9 6.1 0.2 3.4 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) DDE_Tnp_4 PF13359.6 EGC30137.1 - 1.8e-09 37.5 0.0 2.3e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC30137.1 - 0.0005 19.8 0.1 0.00066 19.4 0.1 1.2 1 0 0 1 1 1 1 Transposase DDE domain Vinculin PF01044.19 EGC30138.1 - 5.5e-06 24.9 0.2 5.5e-06 24.9 0.2 1.0 1 0 0 1 1 1 1 Vinculin family Spidroin_N PF16763.5 EGC30138.1 - 0.0079 16.2 0.6 0.37 10.8 0.6 2.0 1 1 0 1 1 1 1 Major ampullate spidroin 1, spider silk protein 1, N-term DUF3430 PF11912.8 EGC30139.1 - 1.1e-17 64.8 31.9 1.3e-17 64.6 31.2 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Cys_Met_Meta_PP PF01053.20 EGC30140.1 - 5.6e-25 87.7 0.2 6.9e-25 87.4 0.2 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGC30140.1 - 3.1e-06 26.6 0.1 4.7e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2738 PF10927.8 EGC30140.1 - 0.002 17.2 0.1 0.0035 16.5 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) zf-C3HC4_3 PF13920.6 EGC30142.1 - 0.00032 20.5 12.1 0.00032 20.5 12.1 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30142.1 - 0.00054 19.8 11.9 0.00054 19.8 11.9 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC30142.1 - 0.0012 19.2 10.8 0.0012 19.2 10.8 3.3 2 1 0 2 2 2 1 Ring finger domain zf-U11-48K PF05253.12 EGC30142.1 - 0.0077 16.1 0.4 6.9 6.7 0.1 3.0 2 0 0 2 2 2 2 U11-48K-like CHHC zinc finger zf-RING_5 PF14634.6 EGC30142.1 - 0.02 14.9 11.5 0.02 14.9 11.5 3.2 2 1 0 2 2 2 0 zinc-RING finger domain zf-TRAF PF02176.18 EGC30142.1 - 4.1 8.2 37.3 0.84 10.4 0.2 4.9 2 1 3 5 5 5 0 TRAF-type zinc finger zf-TRAF PF02176.18 EGC30143.1 - 4.3e-09 36.9 42.8 1.8e-08 35.0 9.6 5.3 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC30143.1 - 0.0013 18.6 12.1 0.0013 18.6 12.1 3.0 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30143.1 - 0.0021 17.9 11.9 0.0021 17.9 11.9 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-U11-48K PF05253.12 EGC30143.1 - 0.0038 17.1 0.6 6.9 6.7 0.0 4.0 3 0 0 3 3 3 2 U11-48K-like CHHC zinc finger zf-RING_2 PF13639.6 EGC30143.1 - 0.0045 17.3 10.8 0.0045 17.3 10.8 4.0 4 1 1 5 5 5 1 Ring finger domain Sina PF03145.16 EGC30143.1 - 0.01 15.8 20.1 0.23 11.4 8.4 3.2 1 1 1 2 2 2 0 Seven in absentia protein family Rsm1 PF08600.10 EGC30143.1 - 0.012 15.8 0.6 0.051 13.7 0.2 2.4 1 1 0 1 1 1 0 Rsm1-like zf-TRAF_2 PF15965.5 EGC30143.1 - 0.043 14.3 31.8 0.62 10.6 5.7 4.0 1 1 2 3 3 3 0 TRAF-like zinc-finger HCO3_cotransp PF00955.21 EGC30144.1 - 0.8 8.5 9.3 1.2 7.9 9.3 1.2 1 0 0 1 1 1 0 HCO3- transporter family Presenilin PF01080.17 EGC30144.1 - 1.6 7.4 10.4 2.3 6.9 10.4 1.2 1 0 0 1 1 1 0 Presenilin Mito_carr PF00153.27 EGC30145.1 - 2.5e-50 168.4 9.5 5e-23 80.8 0.4 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein PAC3 PF10178.9 EGC30147.1 - 0.0085 16.2 0.0 4.5 7.5 0.0 2.8 2 0 0 2 2 2 2 Proteasome assembly chaperone 3 zf-C2H2_7 PF15269.6 EGC30147.1 - 1.6 8.9 4.9 52 4.0 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger TMPIT PF07851.13 EGC30148.1 - 0.65 9.2 26.1 0.12 11.6 13.5 2.0 2 0 0 2 2 2 0 TMPIT-like protein UPF0258 PF06789.12 EGC30149.1 - 0.17 12.0 5.1 0.42 10.7 5.1 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0258) NADH5_C PF06455.11 EGC30150.1 - 0.022 14.4 4.0 0.14 11.8 0.8 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus DUF4064 PF13273.6 EGC30150.1 - 0.059 13.7 4.6 0.38 11.1 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Wzy_C PF04932.15 EGC30150.1 - 0.8 9.3 6.7 1.7 8.3 2.7 2.2 2 1 0 2 2 2 0 O-Antigen ligase DUF4229 PF14012.6 EGC30150.1 - 4.4 7.5 0.0 4.4 7.5 0.0 3.6 3 1 1 4 4 4 0 Protein of unknown function (DUF4229) PARP PF00644.20 EGC30151.1 - 2.2e-51 174.2 0.1 7e-51 172.6 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC30151.1 - 3.6e-38 130.7 4.8 6.7e-38 129.9 4.8 1.5 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGC30151.1 - 4.2e-19 68.4 1.1 1.9e-18 66.3 0.4 2.6 2 1 1 3 3 3 1 WGR domain PADR1 PF08063.12 EGC30151.1 - 1e-14 54.0 0.9 1e-14 54.0 0.9 1.8 2 0 0 2 2 2 1 PADR1 (NUC008) domain zf-PARP PF00645.18 EGC30151.1 - 4.7e-13 49.8 0.1 1.2e-12 48.5 0.1 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region SEEEED PF14797.6 EGC30153.1 - 0.0078 16.4 33.0 0.0078 16.4 33.0 2.0 2 0 0 2 2 2 1 Serine-rich region of AP3B1, clathrin-adaptor complex Nop14 PF04147.12 EGC30153.1 - 2 6.5 21.0 2.6 6.2 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.14 EGC30153.1 - 7.5 4.7 15.4 9.6 4.4 15.4 1.4 1 0 0 1 1 1 0 CDC45-like protein RCC1 PF00415.18 EGC30154.1 - 3.7e-58 194.0 11.9 5.4e-12 46.1 0.1 6.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC30154.1 - 5.9e-31 105.6 19.1 2.5e-06 27.1 0.1 8.3 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat TIR_2 PF13676.6 EGC30154.1 - 0.009 16.6 0.0 0.38 11.4 0.0 3.3 2 2 0 2 2 2 1 TIR domain Pepsin-I3 PF06394.13 EGC30154.1 - 0.13 12.4 0.1 0.7 10.1 0.0 2.2 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain LETM1 PF07766.13 EGC30155.1 - 2.1e-16 60.1 1.4 3.9e-16 59.2 1.4 1.4 1 0 0 1 1 1 1 LETM1-like protein HSCB_C PF07743.13 EGC30155.1 - 0.1 13.1 0.0 0.52 10.8 0.0 2.2 1 0 0 1 1 1 0 HSCB C-terminal oligomerisation domain Cyt-b5 PF00173.28 EGC30156.1 - 4.1e-25 87.7 0.3 4.4e-25 87.6 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain U62_UL91 PF17442.2 EGC30156.1 - 0.07 13.1 0.1 0.11 12.5 0.1 1.3 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins PI3_PI4_kinase PF00454.27 EGC30157.1 - 1.7e-40 139.4 0.8 1.6e-37 129.6 0.8 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC30157.1 - 5e-23 81.5 1.4 7.3e-23 80.9 0.3 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) AAA_6 PF12774.7 EGC30157.1 - 0.011 14.8 0.1 0.022 13.7 0.1 1.4 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region CGI-121 PF08617.10 EGC30158.1 - 1e-29 103.7 2.5 1.2e-29 103.5 2.5 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 B3_4 PF03483.17 EGC30158.1 - 0.046 13.4 0.2 0.07 12.8 0.2 1.4 1 1 0 1 1 1 0 B3/4 domain Pox_E8 PF03394.13 EGC30158.1 - 0.048 13.2 0.2 0.085 12.4 0.2 1.3 1 1 0 1 1 1 0 Poxvirus E8 protein RasGEF PF00617.19 EGC30159.1 - 6e-59 199.2 0.6 1.7e-58 197.7 0.6 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGC30159.1 - 2.9e-26 91.7 1.2 2.9e-26 91.7 1.2 2.5 3 0 0 3 3 3 1 RasGEF N-terminal motif UDG PF03167.19 EGC30160.1 - 8.6e-25 87.5 0.0 1.4e-24 86.8 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily RR_TM4-6 PF06459.12 EGC30160.1 - 9.5 6.0 24.0 15 5.3 24.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 ACC_central PF08326.12 EGC30161.1 - 3.4e-189 630.6 10.9 4.9e-189 630.1 10.9 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.22 EGC30161.1 - 7.3e-161 536.1 0.0 1e-160 535.7 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.17 EGC30161.1 - 1.7e-52 178.0 0.0 4.1e-52 176.8 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGC30161.1 - 7.2e-30 103.8 0.1 1.6e-29 102.7 0.1 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGC30161.1 - 7.7e-20 71.0 0.0 1.9e-19 69.7 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGC30161.1 - 1.6e-09 37.5 0.0 3.5e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.22 EGC30161.1 - 1.1e-07 31.6 0.3 2.8e-07 30.3 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.14 EGC30161.1 - 7.2e-05 22.9 0.0 0.00018 21.6 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.13 EGC30161.1 - 0.00046 19.8 0.0 0.0011 18.5 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.6 EGC30161.1 - 0.073 12.8 0.0 0.17 11.7 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon Init_tRNA_PT PF04179.12 EGC30161.1 - 5.3 7.4 6.6 1.7 9.0 0.1 3.1 4 0 0 4 4 4 0 Rit1 DUSP-like domain GTP_EFTU PF00009.27 EGC30162.1 - 1e-62 211.1 0.1 1.5e-62 210.6 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGC30162.1 - 3.3e-30 104.3 0.0 7e-30 103.3 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.24 EGC30162.1 - 9.3e-20 70.5 0.0 3e-19 68.8 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC30162.1 - 4.3e-15 55.9 0.2 1.2e-14 54.4 0.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGC30162.1 - 2.8e-14 53.0 0.1 7.1e-14 51.7 0.0 1.8 2 0 0 2 2 2 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGC30162.1 - 0.011 15.8 0.0 0.033 14.3 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase COBRA1 PF06209.13 EGC30164.1 - 0.0037 16.2 1.2 0.0042 16.0 1.2 1.0 1 0 0 1 1 1 1 Cofactor of BRCA1 (COBRA1) Myb_DNA-binding PF00249.31 EGC30164.1 - 0.0057 16.8 0.1 0.031 14.5 0.1 2.0 1 1 0 1 1 1 1 Myb-like DNA-binding domain ERGIC_N PF13850.6 EGC30164.1 - 0.04 14.2 0.2 0.075 13.4 0.0 1.6 2 0 0 2 2 2 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3Hc3H PF13891.6 EGC30165.1 - 3.4e-34 117.0 15.8 2.2e-17 63.2 4.3 2.7 2 0 0 2 2 2 2 Potential DNA-binding domain zf-primase PF09329.11 EGC30165.1 - 0.0098 15.7 1.5 0.58 10.0 0.4 2.9 2 0 0 2 2 2 1 Primase zinc finger CxC6 PF18721.1 EGC30165.1 - 7.5 6.9 13.3 4.8 7.5 1.1 4.1 2 2 1 3 3 3 0 CxC6 like cysteine cluster associated with KDZ transposases Peptidase_S49_N PF08496.10 EGC30166.1 - 0.14 12.2 6.5 0.19 11.8 6.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Tmemb_161AB PF10268.9 EGC30166.1 - 1.6 7.3 3.1 2.1 6.9 3.1 1.1 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB Peptidase_C1 PF00112.23 EGC30167.1 - 2.5e-61 207.5 6.2 2.5e-61 207.5 6.2 1.4 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC30167.1 - 1.4e-15 57.5 8.5 2.3e-15 56.7 8.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC30167.1 - 3.8e-05 22.6 0.0 0.007 15.2 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family IRF PF00605.17 EGC30167.1 - 0.085 13.2 0.2 0.18 12.1 0.2 1.5 1 0 0 1 1 1 0 Interferon regulatory factor transcription factor HSP20 PF00011.21 EGC30168.1 - 6.3e-17 61.6 0.5 1e-16 60.9 0.5 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC30168.1 - 2.6e-08 33.3 0.0 4.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA MA3 PF02847.17 EGC30168.1 - 0.022 14.7 0.3 0.041 13.9 0.3 1.4 1 0 0 1 1 1 0 MA3 domain CS PF04969.16 EGC30168.1 - 0.11 13.6 3.0 0.13 13.3 1.6 2.0 2 1 0 2 2 2 0 CS domain DnaJ PF00226.31 EGC30171.1 - 1.4e-24 86.0 0.9 1.4e-24 86.0 0.9 2.8 2 0 0 2 2 2 1 DnaJ domain zf-C2H2_jaz PF12171.8 EGC30171.1 - 1.8e-09 37.6 14.7 7.1e-09 35.7 8.2 3.1 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGC30171.1 - 1.2e-06 28.7 2.8 1.2e-06 28.7 2.8 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGC30171.1 - 3.8e-05 24.2 4.7 0.17 12.8 0.8 3.0 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2 PF00096.26 EGC30171.1 - 9.9e-05 22.6 8.1 0.007 16.8 1.8 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_2 PF12756.7 EGC30171.1 - 0.0078 16.5 19.4 0.12 12.7 1.6 3.6 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.6 EGC30171.1 - 0.094 12.7 4.5 1.1 9.3 1.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PP-binding PF00550.25 EGC30172.1 - 3.4e-06 27.3 0.1 0.00057 20.2 0.0 2.0 2 0 0 2 2 2 2 Phosphopantetheine attachment site Fz PF01392.22 EGC30173.1 - 1.3e-05 25.8 6.6 3.1e-05 24.6 6.6 1.6 1 0 0 1 1 1 1 Fz domain Ras PF00071.22 EGC30174.1 - 2.7e-52 176.7 0.0 1e-51 174.8 0.0 1.9 2 0 0 2 2 2 1 Ras family BTB PF00651.31 EGC30174.1 - 1.1e-32 112.6 2.5 2.2e-17 63.3 0.1 3.4 2 1 0 2 2 2 2 BTB/POZ domain Roc PF08477.13 EGC30174.1 - 9e-22 77.5 0.0 1.8e-21 76.5 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30174.1 - 8e-07 28.7 0.0 2.8e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family BTB_3 PF16017.5 EGC30174.1 - 0.0061 16.7 0.6 0.75 9.9 0.0 2.9 3 0 0 3 3 3 1 BTB/POZ domain GTP_EFTU PF00009.27 EGC30174.1 - 0.043 13.3 0.0 0.088 12.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain BACK PF07707.15 EGC30174.1 - 0.088 12.9 0.1 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch DUF4261 PF14080.6 EGC30174.1 - 0.14 12.3 0.1 0.67 10.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4261) LRR_4 PF12799.7 EGC30175.1 - 9.7e-19 67.2 67.1 1.2e-05 25.5 0.2 10.6 7 4 4 11 11 11 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC30175.1 - 1e-16 60.4 45.8 8.2e-09 35.1 3.8 6.6 3 1 5 8 8 8 5 Leucine rich repeat LRR_6 PF13516.6 EGC30175.1 - 1.4e-09 37.2 40.7 0.011 15.7 0.2 11.3 10 1 1 11 11 11 4 Leucine Rich repeat LRR_2 PF07723.13 EGC30175.1 - 0.055 14.2 2.6 35 5.3 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_1 PF00560.33 EGC30175.1 - 1.1 10.1 42.7 8.2 7.4 1.2 10.8 11 2 0 11 11 11 0 Leucine Rich Repeat LIDHydrolase PF10230.9 EGC30176.1 - 3e-61 207.3 0.3 3.7e-61 207.0 0.3 1.1 1 0 0 1 1 1 1 Lipid-droplet associated hydrolase Hydrolase_4 PF12146.8 EGC30176.1 - 0.00017 21.0 0.0 0.00029 20.2 0.0 1.4 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGC30176.1 - 0.012 15.2 0.1 0.32 10.6 0.0 2.3 2 1 0 2 2 2 0 alpha/beta hydrolase fold Tyr-DNA_phospho PF06087.12 EGC30176.1 - 0.03 13.2 0.0 0.045 12.6 0.0 1.2 1 0 0 1 1 1 0 Tyrosyl-DNA phosphodiesterase HEPN_Apea PF18739.1 EGC30176.1 - 0.058 13.8 0.3 0.058 13.8 0.3 2.0 2 1 0 2 2 2 0 Apea-like HEPN Abhydrolase_2 PF02230.16 EGC30176.1 - 0.13 12.0 0.0 0.47 10.2 0.0 1.7 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.20 EGC30177.1 - 1.3e-14 54.5 0.0 2.6e-12 46.9 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC30177.1 - 2.7e-11 43.2 0.0 7.1e-11 41.8 0.0 1.6 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC30177.1 - 1.6e-07 32.1 0.0 2.1e-07 31.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGC30177.1 - 0.00032 20.4 0.0 0.011 15.4 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.18 EGC30177.1 - 0.086 12.4 0.0 4.5 6.8 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EGC30177.1 - 0.1 12.7 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Thioesterase domain Ndr PF03096.14 EGC30177.1 - 0.11 11.2 0.0 0.19 10.4 0.0 1.4 2 0 0 2 2 2 0 Ndr family Carm_PH PF17888.1 EGC30178.1 - 6.7e-07 29.6 0.1 1.8e-06 28.2 0.1 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_6 PF13516.6 EGC30178.1 - 0.00012 21.8 24.4 0.038 14.1 0.0 8.1 10 0 0 10 10 10 3 Leucine Rich repeat LRR_1 PF00560.33 EGC30178.1 - 0.0011 19.2 16.6 8.3 7.4 0.1 8.5 7 1 0 7 7 7 1 Leucine Rich Repeat LRR_4 PF12799.7 EGC30178.1 - 0.0025 18.2 0.8 0.0025 18.2 0.8 6.8 7 2 1 8 8 7 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC30178.1 - 0.13 12.1 11.7 9.9 6.0 0.8 5.7 5 0 0 5 5 5 0 Leucine rich repeat TFIIA PF03153.13 EGC30178.1 - 0.32 10.9 28.0 0.78 9.7 23.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGC30178.1 - 0.91 9.1 29.7 2.9 7.4 22.0 2.6 2 0 0 2 2 2 0 Spt20 family Dsl1_C PF11989.8 EGC30178.1 - 6.7 6.4 9.9 0.42 10.3 0.1 3.1 3 0 0 3 3 3 0 Retrograde transport protein Dsl1 C terminal bZIP_Maf PF03131.17 EGC30180.1 - 5.5e-08 33.2 11.7 5.5e-08 33.2 11.7 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.21 EGC30180.1 - 1.2e-07 31.7 14.5 1.2e-07 31.7 14.5 2.1 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC30180.1 - 0.0095 16.0 11.1 0.0095 16.0 11.1 2.3 2 1 0 2 2 2 1 Basic region leucine zipper Exonuc_VII_L PF02601.15 EGC30180.1 - 1.2 8.7 10.1 0.67 9.5 6.5 2.0 2 0 0 2 2 2 0 Exonuclease VII, large subunit L31 PF09784.9 EGC30180.1 - 1.4 9.3 12.8 1.3 9.5 6.2 2.6 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 FlaC_arch PF05377.11 EGC30180.1 - 1.9 8.9 10.0 0.095 13.1 2.5 2.6 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) DUF3450 PF11932.8 EGC30180.1 - 5.4 6.2 15.8 0.98 8.7 10.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1108 PF06531.11 EGC30181.1 - 0.017 15.4 0.0 0.029 14.6 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1108) Methyltransf_23 PF13489.6 EGC30182.1 - 1.3e-17 64.1 0.1 3e-17 62.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC30182.1 - 2.2e-15 57.2 3.6 5e-14 52.9 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30182.1 - 1.5e-13 51.3 0.0 3.1e-13 50.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC30182.1 - 2.5e-12 46.9 0.0 5.9e-12 45.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC30182.1 - 4.9e-10 39.9 0.0 1.1e-09 38.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC30182.1 - 1e-06 28.3 0.0 3.7e-06 26.5 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC30182.1 - 5.5e-06 26.0 0.0 1.3e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_2 PF00891.18 EGC30182.1 - 0.00046 19.5 0.0 0.00067 19.0 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain CheR PF01739.18 EGC30182.1 - 0.0026 17.3 0.0 1.9 7.9 0.0 2.5 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain Methyltransf_16 PF10294.9 EGC30182.1 - 0.0028 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Lysine methyltransferase DUF938 PF06080.12 EGC30182.1 - 0.0077 16.0 0.0 0.012 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_4 PF02390.17 EGC30182.1 - 0.29 10.6 0.0 0.29 10.6 0.0 2.7 3 0 0 3 3 3 0 Putative methyltransferase RhoGEF PF00621.20 EGC30183.1 - 8.1e-31 107.7 7.1 8.1e-31 107.7 7.1 3.4 3 0 0 3 3 3 1 RhoGEF domain FYVE PF01363.21 EGC30183.1 - 1.1e-19 70.4 7.1 2.4e-19 69.2 7.1 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGC30183.1 - 5.9e-07 30.0 3.3 7e-07 29.7 0.3 2.7 2 1 0 2 2 2 1 PH domain FYVE_2 PF02318.16 EGC30183.1 - 0.0017 18.5 3.6 0.0017 18.5 3.6 2.6 3 0 0 3 3 3 1 FYVE-type zinc finger CPSF73-100_C PF11718.8 EGC30185.1 - 4.1e-55 186.7 5.0 9.2e-55 185.5 5.0 1.6 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.8 EGC30185.1 - 6.4e-30 103.7 0.0 2.2e-29 102.0 0.0 2.0 2 0 0 2 2 2 1 Beta-Casp domain Lactamase_B_6 PF16661.5 EGC30185.1 - 1.5e-22 80.0 0.0 1.1e-21 77.1 0.0 2.4 3 0 0 3 3 3 1 Metallo-beta-lactamase superfamily domain Lactamase_B PF00753.27 EGC30185.1 - 7.8e-17 61.9 0.2 1.4e-16 61.1 0.2 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.12 EGC30185.1 - 1.9e-16 59.7 0.0 4.5e-16 58.5 0.0 1.7 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B_2 PF12706.7 EGC30185.1 - 3.6e-07 29.9 0.2 1.5e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGC30185.1 - 5.2e-06 26.4 0.1 3.3e-05 23.9 0.0 2.3 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Beta_lactamase3 PF17030.5 EGC30185.1 - 0.00024 20.4 0.0 0.00024 20.4 0.0 2.2 3 0 0 3 3 3 1 Putative beta-lactamase-like family CPW_WPC PF09717.10 EGC30186.1 - 0.048 14.6 22.6 83 4.3 3.3 5.6 1 1 1 2 2 2 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Response_reg PF00072.24 EGC30187.1 - 8.9e-26 90.3 0.1 1.3e-19 70.4 0.1 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGC30187.1 - 3.1e-21 76.0 0.5 1.7e-20 73.6 0.2 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGC30187.1 - 2.8e-12 46.5 0.4 2.8e-12 46.5 0.4 2.0 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Nucleoporin_FG PF13634.6 EGC30189.1 - 2.2e-07 31.6 66.5 0.012 16.5 33.9 3.4 1 1 3 4 4 4 3 Nucleoporin FG repeat region FliW PF02623.15 EGC30189.1 - 0.069 13.1 0.7 0.21 11.5 0.7 1.8 1 0 0 1 1 1 0 FliW protein ZirS_C PF16583.5 EGC30189.1 - 0.1 12.2 0.7 0.36 10.4 0.7 2.0 1 1 0 1 1 1 0 Zinc-regulated secreted antivirulence protein C-terminal domain Stealth_CR2 PF11380.8 EGC30190.1 - 0.029 14.6 2.7 1.3 9.3 0.1 2.7 2 0 0 2 2 2 0 Stealth protein CR2, conserved region 2 Arginase PF00491.21 EGC30191.1 - 1e-14 54.7 0.0 1.2e-13 51.3 0.0 1.9 2 0 0 2 2 2 1 Arginase family BTB PF00651.31 EGC30192.1 - 0.0022 18.2 2.4 0.024 14.9 0.3 3.0 2 1 1 3 3 3 1 BTB/POZ domain Arm PF00514.23 EGC30192.1 - 0.0023 17.9 0.4 61 3.9 0.0 4.8 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.7 EGC30192.1 - 0.0032 18.0 1.5 0.23 12.1 0.2 2.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region Macoilin PF09726.9 EGC30193.1 - 3.2 6.2 18.1 0.5 8.9 14.2 1.5 1 1 1 2 2 2 0 Macoilin family Kelch_1 PF01344.25 EGC30194.1 - 1.1e-37 127.3 0.6 1.2e-07 31.2 0.0 6.9 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EGC30194.1 - 1.4e-31 107.8 6.5 4.9e-07 29.8 0.0 6.4 4 2 2 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC30194.1 - 4.8e-30 103.3 16.5 3.7e-09 36.5 0.0 7.0 6 1 1 7 7 7 6 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC30194.1 - 6.7e-30 102.8 5.3 9.4e-07 29.0 0.0 6.9 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC30194.1 - 1.3e-19 69.7 12.7 0.00031 20.7 0.1 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGC30194.1 - 1.4e-16 59.8 9.9 0.0063 16.5 0.0 6.2 6 0 0 6 6 6 5 Kelch motif F-box-like PF12937.7 EGC30194.1 - 5e-06 26.3 0.2 1.1e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 F-box-like Elongin_A PF06881.11 EGC30194.1 - 0.012 16.1 0.1 0.022 15.3 0.1 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A F-box PF00646.33 EGC30194.1 - 0.023 14.6 0.2 0.047 13.6 0.2 1.6 1 0 0 1 1 1 0 F-box domain Peptidase_M41 PF01434.18 EGC30195.1 - 4.9e-65 219.0 0.1 8e-65 218.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGC30195.1 - 4.2e-42 143.7 0.0 8.8e-42 142.7 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC30195.1 - 9e-12 44.6 0.2 2.6e-11 43.1 0.2 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC30195.1 - 0.00036 20.6 0.3 0.0038 17.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGC30195.1 - 0.0011 19.2 0.2 0.67 10.2 0.1 3.1 3 0 0 3 3 3 1 AAA domain RuvB_N PF05496.12 EGC30195.1 - 0.0015 18.3 0.0 0.004 16.9 0.0 1.8 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGC30195.1 - 0.0021 18.5 0.7 0.39 11.1 0.1 3.4 3 1 0 4 4 4 1 AAA ATPase domain TIP49 PF06068.13 EGC30195.1 - 0.0098 15.1 0.1 0.021 14.1 0.1 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGC30195.1 - 0.028 14.6 0.0 0.092 12.9 0.0 2.0 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC30195.1 - 0.042 13.1 0.5 0.32 10.2 0.1 2.4 2 1 1 3 3 3 0 Zeta toxin IstB_IS21 PF01695.17 EGC30195.1 - 0.042 13.6 0.0 0.079 12.7 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_2 PF07724.14 EGC30195.1 - 0.063 13.4 3.3 0.064 13.4 0.0 2.7 2 1 0 2 2 1 0 AAA domain (Cdc48 subfamily) AAA_25 PF13481.6 EGC30195.1 - 0.1 12.1 0.1 0.44 10.1 0.1 2.1 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGC30195.1 - 0.13 11.6 0.4 0.37 10.2 0.4 1.7 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_11 PF13086.6 EGC30195.1 - 0.16 11.7 8.4 5.1 6.8 4.7 2.3 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC30195.1 - 0.2 12.2 5.2 0.76 10.3 0.0 3.3 3 0 0 3 3 2 0 AAA domain Presenilin PF01080.17 EGC30195.1 - 3.3 6.4 4.8 4.5 5.9 4.8 1.2 1 0 0 1 1 1 0 Presenilin SLX9 PF15341.6 EGC30196.1 - 0.38 11.2 11.9 0.61 10.5 11.9 1.4 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 TIG PF01833.24 EGC30197.1 - 0.00011 22.2 0.6 0.00024 21.1 0.6 1.6 1 0 0 1 1 1 1 IPT/TIG domain DUF2606 PF10794.9 EGC30197.1 - 0.013 15.2 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2606) Arf PF00025.21 EGC30199.1 - 3.2e-60 202.6 0.4 3.6e-60 202.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC30199.1 - 9.2e-13 48.5 0.1 1.3e-12 47.9 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC30199.1 - 1.5e-12 47.4 0.0 1.8e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC30199.1 - 6.9e-11 41.9 0.1 8.8e-11 41.6 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC30199.1 - 1.9e-05 24.0 0.2 0.002 17.4 0.0 2.5 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.23 EGC30199.1 - 4.2e-05 23.6 0.1 5.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC30199.1 - 9.9e-05 21.8 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 EGC30199.1 - 0.01 15.9 0.2 0.068 13.2 0.2 1.9 1 1 1 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC30199.1 - 0.015 15.6 0.2 0.031 14.6 0.2 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGC30199.1 - 0.046 13.4 0.1 0.17 11.5 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EGC30199.1 - 0.062 13.8 0.2 0.11 13.0 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AbiEi_3_N PF17194.4 EGC30199.1 - 0.1 12.6 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 Transcriptional regulator, AbiEi antitoxin N-terminal domain UPF0147 PF03685.13 EGC30200.1 - 0.01 15.8 0.0 0.022 14.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) EbsA PF17255.2 EGC30200.1 - 0.026 14.9 1.4 0.22 11.9 0.0 2.8 3 0 0 3 3 3 0 EbsA-like protein Phage_holin_5_2 PF16079.5 EGC30200.1 - 0.12 12.7 0.1 24 5.3 0.0 2.7 2 0 0 2 2 2 0 Phage holin family Hol44, in holin superfamily V Copine PF07002.16 EGC30201.1 - 5.7e-61 205.7 0.0 6.8e-61 205.5 0.0 1.1 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.9 EGC30201.1 - 1.6e-11 44.7 0.0 2.2e-11 44.3 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF4870 PF09685.10 EGC30202.1 - 0.013 15.6 1.4 0.016 15.3 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4870) EI24 PF07264.11 EGC30204.1 - 0.015 15.6 2.3 0.015 15.6 2.3 1.8 2 0 0 2 2 2 0 Etoposide-induced protein 2.4 (EI24) Adipogenin PF15202.6 EGC30204.1 - 0.016 15.2 0.3 0.016 15.2 0.3 2.2 2 0 0 2 2 2 0 Adipogenin DUF2628 PF10947.8 EGC30204.1 - 0.84 10.0 0.0 0.84 10.0 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2628) EamA PF00892.20 EGC30204.1 - 0.88 9.7 13.6 8.8 6.5 7.4 3.0 3 0 0 3 3 3 0 EamA-like transporter family Claudin_3 PF06653.11 EGC30204.1 - 3 7.8 13.9 11 6.0 0.0 2.5 3 0 0 3 3 3 0 Tight junction protein, Claudin-like OAD_gamma PF04277.13 EGC30205.1 - 0.68 10.6 5.4 9.3 6.9 5.4 2.7 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Kelch_6 PF13964.6 EGC30206.1 - 1.8e-11 43.9 4.5 0.0062 16.8 0.0 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGC30206.1 - 9e-10 38.0 12.7 9.3e-05 21.9 0.0 5.3 6 0 0 6 6 6 3 Kelch motif Kelch_4 PF13418.6 EGC30206.1 - 0.00043 20.2 7.3 0.56 10.3 0.1 4.4 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC30206.1 - 0.0073 16.6 6.8 2.2 8.7 0.2 5.1 5 0 0 5 5 5 1 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC30206.1 - 0.012 15.6 12.0 0.45 10.6 0.0 4.6 5 0 0 5 5 5 0 Kelch motif Kelch_2 PF07646.15 EGC30206.1 - 0.055 13.5 7.1 5.2 7.2 0.0 4.3 5 0 0 5 5 5 0 Kelch motif BUD22 PF09073.10 EGC30208.1 - 0.0029 17.0 16.9 0.0029 17.0 16.9 1.8 2 0 0 2 2 2 1 BUD22 Pre-PUA PF17832.1 EGC30209.1 - 3.3e-26 91.8 0.5 5.8e-26 91.0 0.5 1.4 1 0 0 1 1 1 1 Pre-PUA-like domain PUA PF01472.20 EGC30209.1 - 1.7e-16 59.9 0.2 3e-16 59.1 0.2 1.4 1 0 0 1 1 1 1 PUA domain DUF1947 PF09183.10 EGC30209.1 - 0.055 13.8 0.4 0.16 12.3 0.4 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF1947) DUF4292 PF14125.6 EGC30209.1 - 0.08 12.6 0.3 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4292) FNIP PF05725.12 EGC30210.1 - 1.7e-55 184.9 110.6 1.3e-10 41.2 6.8 13.1 6 4 7 13 13 13 11 FNIP Repeat Pkinase PF00069.25 EGC30210.1 - 2.3e-44 151.7 0.6 4.4e-44 150.8 0.6 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30210.1 - 1e-30 106.9 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC30210.1 - 3.3e-07 29.4 0.3 5e-07 28.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC30210.1 - 0.00052 19.4 0.0 0.00094 18.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC30210.1 - 0.013 15.4 0.0 0.021 14.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC30210.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.9 EGC30210.1 - 0.024 14.2 0.0 0.041 13.4 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.20 EGC30210.1 - 0.07 12.7 0.4 0.14 11.8 0.4 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FNIP PF05725.12 EGC30211.1 - 6.6e-62 205.4 134.0 1.7e-11 44.1 0.8 13.1 8 3 7 15 15 15 14 FNIP Repeat Pkinase PF00069.25 EGC30211.1 - 8.7e-46 156.4 0.9 2.8e-45 154.8 0.9 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30211.1 - 1.8e-29 102.8 0.0 9.7e-29 100.4 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC30211.1 - 4.2e-07 29.1 0.2 6.6e-07 28.4 0.2 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC30211.1 - 0.00015 21.2 0.0 0.00026 20.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC30211.1 - 0.0092 15.9 0.0 0.014 15.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGC30211.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.14 EGC30211.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGC30211.1 - 0.07 12.7 0.5 0.15 11.7 0.5 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase PRKCSH_1 PF13015.6 EGC30213.1 - 0.071 12.8 0.8 0.14 11.8 0.8 1.6 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein OCRE PF17780.1 EGC30213.1 - 0.22 11.6 1.1 0.29 11.2 0.1 1.7 2 0 0 2 2 2 0 OCRE domain CttA_N PF18244.1 EGC30213.1 - 0.49 10.9 3.4 0.8 10.2 1.0 2.2 2 1 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain Cyclin PF08613.11 EGC30214.1 - 7.1e-24 85.0 25.4 7.1e-24 85.0 25.4 5.5 2 2 0 2 2 2 1 Cyclin Cyclin_N PF00134.23 EGC30214.1 - 3.4e-09 36.5 0.1 3.4e-09 36.5 0.1 2.7 3 1 0 3 3 3 1 Cyclin, N-terminal domain NEMP PF10225.9 EGC30214.1 - 0.069 12.8 0.3 0.069 12.8 0.3 3.1 3 0 0 3 3 3 0 NEMP family Herpes_UL37_2 PF07413.11 EGC30215.1 - 0.051 12.8 3.1 0.091 12.0 3.1 1.4 1 0 0 1 1 1 0 Betaherpesvirus immediate-early glycoprotein UL37 Autophagy_C PF10381.9 EGC30215.1 - 0.22 11.1 1.5 14 5.3 0.1 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal MPP6 PF10175.9 EGC30216.1 - 2.2e-13 50.8 37.9 5.3e-12 46.4 37.9 2.5 1 1 0 1 1 1 1 M-phase phosphoprotein 6 Utp14 PF04615.13 EGC30216.1 - 0.003 16.2 30.9 0.0034 16.0 30.9 1.0 1 0 0 1 1 1 1 Utp14 protein DUF3546 PF12066.8 EGC30217.1 - 4e-25 88.2 12.1 4e-25 88.2 12.1 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.13 EGC30217.1 - 3.5e-16 60.2 3.4 3.5e-16 60.2 3.4 3.7 3 1 2 5 5 5 1 Arsenite-resistance protein 2 DUF4187 PF13821.6 EGC30217.1 - 6e-07 29.2 4.2 1.7e-06 27.7 4.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4187) RRM_1 PF00076.22 EGC30217.1 - 1.5e-05 24.7 0.0 4.4e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_2 PF12756.7 EGC30217.1 - 0.15 12.4 8.4 0.18 12.1 1.5 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGC30217.1 - 0.55 11.2 9.9 0.92 10.5 0.8 2.9 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2 PF00096.26 EGC30217.1 - 0.96 10.0 10.8 0.065 13.7 0.8 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-C2H2_jaz PF12171.8 EGC30217.1 - 1 9.7 12.3 0.63 10.4 1.4 2.7 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding Dicty_spore_N PF04562.12 EGC30218.1 - 2.7e-21 76.4 28.0 2.7e-21 76.4 28.0 5.0 2 1 2 4 4 4 2 Dictyostelium spore coat protein, N terminus PPR PF01535.20 EGC30219.1 - 0.0029 17.7 0.5 2.4 8.6 0.0 4.1 4 0 0 4 4 4 2 PPR repeat PPR_2 PF13041.6 EGC30219.1 - 0.087 13.0 2.4 2.2 8.5 0.0 4.5 6 0 0 6 6 6 0 PPR repeat family Tmp39 PF10271.9 EGC30220.1 - 0.042 12.9 2.0 0.079 12.0 2.0 1.3 1 0 0 1 1 1 0 Putative transmembrane protein LIN52 PF10044.9 EGC30220.1 - 3.3 8.5 9.2 4 8.2 5.0 3.2 2 0 0 2 2 2 0 Retinal tissue protein Gly_kinase PF02595.15 EGC30221.1 - 8.8e-88 294.7 0.0 1e-87 294.5 0.0 1.0 1 0 0 1 1 1 1 Glycerate kinase family Vps51 PF08700.11 EGC30222.1 - 7.8e-11 41.9 4.4 7.8e-11 41.9 4.4 5.3 5 1 0 5 5 5 1 Vps51/Vps67 TFIIA PF03153.13 EGC30222.1 - 0.00016 21.8 22.8 0.00016 21.8 22.8 4.7 5 0 0 5 5 5 3 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 EGC30222.1 - 3.5 8.3 8.1 15 6.2 8.1 2.1 1 0 0 1 1 1 0 60s Acidic ribosomal protein Ribosomal_S27e PF01667.17 EGC30223.1 - 3.7e-24 84.2 3.2 4.5e-24 83.9 3.2 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 DUF3795 PF12675.7 EGC30223.1 - 0.028 14.8 1.1 0.079 13.4 0.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3795) Prok-RING_1 PF14446.6 EGC30223.1 - 0.062 13.2 1.3 0.098 12.6 1.3 1.3 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 zf-CSL PF05207.13 EGC30223.1 - 0.71 9.6 3.6 1.2 8.9 3.6 1.5 1 1 0 1 1 1 0 CSL zinc finger zf-LSD1 PF06943.12 EGC30223.1 - 1.2 9.1 6.5 0.46 10.4 2.0 2.3 2 1 1 3 3 3 0 LSD1 zinc finger DUF2012 PF09430.10 EGC30224.1 - 1.9e-12 47.3 0.2 2.9e-12 46.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) MIT PF04212.18 EGC30225.1 - 4.9e-09 36.1 0.7 4.9e-09 36.1 0.7 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain NRBF2_MIT PF17169.4 EGC30225.1 - 0.0038 17.4 0.7 0.011 16.0 0.7 1.7 1 0 0 1 1 1 1 MIT domain of nuclear receptor-binding factor 2 Csm1_N PF18504.1 EGC30225.1 - 0.34 11.3 15.8 4.3 7.8 2.6 3.1 2 0 0 2 2 2 0 Csm1 N-terminal domain FH2 PF02181.23 EGC30227.1 - 8.1e-58 196.3 1.5 2.1e-57 194.9 1.5 1.7 1 0 0 1 1 1 1 Formin Homology 2 Domain DUF3361 PF11841.8 EGC30227.1 - 6.4e-10 39.2 0.0 2.5e-09 37.3 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) Drf_GBD PF06371.13 EGC30227.1 - 0.0007 19.2 0.0 0.0007 19.2 0.0 2.1 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain NurA PF09376.10 EGC30227.1 - 0.00093 19.0 0.3 0.11 12.2 0.0 2.4 2 0 0 2 2 2 2 NurA domain Thioredoxin_4 PF13462.6 EGC30227.1 - 2.2 8.4 5.2 0.78 9.9 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin Menin PF05053.13 EGC30227.1 - 8.8 4.6 15.0 17 3.6 15.0 1.4 1 0 0 1 1 1 0 Menin Ank_2 PF12796.7 EGC30229.1 - 9.4e-22 77.4 2.9 1.7e-12 47.7 0.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGC30229.1 - 2.7e-20 71.8 0.3 1e-07 32.1 0.0 3.4 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.6 EGC30229.1 - 4.4e-20 71.5 0.6 1.4e-08 34.8 0.1 2.6 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC30229.1 - 1e-16 61.1 0.4 1.1e-07 32.3 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC30229.1 - 1e-15 56.2 0.4 1.1e-06 28.4 0.1 3.7 4 0 0 4 4 4 3 Ankyrin repeat Lipoprotein_3 PF00938.17 EGC30229.1 - 0.087 13.0 0.2 0.22 11.7 0.2 1.7 1 0 0 1 1 1 0 Lipoprotein Phage_holin_3_1 PF05106.12 EGC30230.1 - 0.046 14.1 0.3 0.085 13.3 0.3 1.5 1 0 0 1 1 1 0 Phage holin family (Lysis protein S) Sec23_helical PF04815.15 EGC30230.1 - 0.091 12.6 0.6 0.24 11.3 0.4 1.9 1 1 1 2 2 2 0 Sec23/Sec24 helical domain Phage_holin_2_3 PF16080.5 EGC30231.1 - 0.1 12.3 1.9 0.17 11.7 0.2 2.1 2 0 0 2 2 2 0 Bacteriophage holin family HP1 7TMR-DISM_7TM PF07695.11 EGC30231.1 - 0.2 11.5 9.8 0.63 9.9 6.1 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling eIF3_subunit PF08597.10 EGC30232.1 - 2.5e-44 152.0 25.9 2.8e-44 151.9 25.9 1.0 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit Binary_toxB_3 PF17476.2 EGC30232.1 - 0.023 14.8 4.0 0.073 13.3 3.7 2.0 1 1 0 1 1 1 0 Clostridial binary toxin B/anthrax toxin PA domain 3 PH_12 PF16457.5 EGC30232.1 - 4.4 7.8 7.5 1.2 9.6 1.3 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain DEAD PF00270.29 EGC30233.1 - 1.5e-51 174.6 0.0 2.3e-49 167.5 0.0 2.2 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC30233.1 - 2.8e-31 108.2 0.1 1.9e-29 102.3 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC30233.1 - 3.5e-05 23.9 1.9 4.4e-05 23.5 0.0 2.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit OTU PF02338.19 EGC30234.1 - 6.4e-12 46.1 0.1 8.2e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease adh_short PF00106.25 EGC30235.1 - 1.7e-25 89.6 1.0 2.2e-23 82.8 0.7 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGC30235.1 - 1.1e-15 57.8 0.0 4.1e-15 56.0 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC30235.1 - 4.4e-09 36.5 0.0 9e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC30235.1 - 1.5e-05 24.6 0.0 1.9e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Pyr_redox_3 PF13738.6 EGC30235.1 - 0.033 13.4 0.6 0.05 12.9 0.1 1.6 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_10 PF13460.6 EGC30235.1 - 0.11 12.4 0.1 0.36 10.7 0.1 1.9 1 1 0 1 1 1 0 NAD(P)H-binding 7tm_2 PF00002.24 EGC30236.1 - 6e-10 38.8 16.0 4.9e-09 35.8 15.5 2.1 2 0 0 2 2 2 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 EGC30236.1 - 1.3 8.0 19.0 1 8.4 14.8 2.4 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region U3_assoc_6 PF08640.11 EGC30237.1 - 1.3e-18 66.9 7.8 1.4e-18 66.7 4.0 2.8 2 0 0 2 2 2 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.6 EGC30237.1 - 0.024 15.4 0.0 47 5.2 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat BORCS7 PF16088.5 EGC30237.1 - 0.05 13.9 1.5 0.23 11.7 0.0 2.9 3 1 0 4 4 4 0 BLOC-1-related complex sub-unit 7 Solute_trans_a PF03619.16 EGC30239.1 - 1.9e-99 332.5 16.6 2.3e-99 332.2 16.6 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha MRP-S28 PF10213.9 EGC30240.1 - 6.6e-10 39.5 0.9 6.6e-10 39.5 0.9 3.1 3 0 0 3 3 3 1 Mitochondrial ribosomal subunit protein POTRA PF07244.15 EGC30240.1 - 0.07 13.7 1.8 1.6 9.4 0.0 3.8 3 1 0 3 3 3 0 Surface antigen variable number repeat DUF5063 PF16702.5 EGC30240.1 - 2.7 8.3 6.9 0.85 10.0 2.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5063) RabGAP-TBC PF00566.18 EGC30241.1 - 2.2e-26 92.8 4.4 2.2e-26 92.8 4.4 2.6 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Tnp_22_trimer PF17489.2 EGC30241.1 - 0.031 14.2 0.3 0.081 12.9 0.3 1.7 1 0 0 1 1 1 0 L1 transposable element trimerization domain DNA_Packaging PF11053.8 EGC30241.1 - 0.96 9.3 3.9 1.7 8.5 0.2 2.3 1 1 1 2 2 2 0 Terminase DNA packaging enzyme Exonuc_VII_L PF02601.15 EGC30241.1 - 1.4 8.4 11.3 2.2 7.8 11.3 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF5446 PF17522.2 EGC30241.1 - 6.6 7.0 9.9 4.3 7.6 1.4 3.3 1 1 2 3 3 3 0 Family of unknown function (DUF5446) EF-hand_1 PF00036.32 EGC30242.1 - 1.2e-41 137.1 12.8 4.7e-10 38.3 0.9 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC30242.1 - 7.8e-36 122.4 2.4 1.5e-18 67.0 0.7 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC30242.1 - 1.6e-32 111.1 10.5 1.2e-15 57.0 0.5 4.0 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.6 EGC30242.1 - 1.6e-30 102.4 6.7 1.2e-09 37.3 0.0 4.5 4 1 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC30242.1 - 7.5e-27 91.6 10.5 1.2e-06 27.7 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.6 EGC30242.1 - 2.3e-14 53.5 0.1 9.1e-09 35.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.9 EGC30242.1 - 5.9e-09 36.2 0.0 0.001 19.3 0.1 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGC30242.1 - 7.4e-09 35.5 0.7 0.0011 18.9 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.13 EGC30242.1 - 7.8e-06 25.8 0.1 0.046 13.8 0.0 3.0 2 1 1 3 3 3 2 Uncharacterised protein family (UPF0154) EF-hand_11 PF08976.11 EGC30242.1 - 8.8e-05 23.3 0.0 0.02 15.7 0.0 2.1 1 1 1 2 2 2 1 EF-hand domain Dockerin_1 PF00404.18 EGC30242.1 - 0.00039 20.6 4.6 0.1 12.8 0.2 3.1 1 1 2 3 3 3 2 Dockerin type I domain EFhand_Ca_insen PF08726.10 EGC30242.1 - 0.00057 19.9 0.5 0.0031 17.6 0.1 2.3 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.13 EGC30242.1 - 0.0013 18.7 1.1 0.83 9.6 0.0 3.5 1 1 3 4 4 4 1 Caleosin related protein DUF3349 PF11829.8 EGC30242.1 - 0.0013 19.4 0.3 3 8.7 0.0 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF3349) DUF4497 PF14924.6 EGC30242.1 - 0.0016 18.9 0.0 0.6 10.6 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF4497) DUF5580 PF17743.1 EGC30242.1 - 0.0016 17.0 0.0 0.0016 17.0 0.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF5580) DUF1103 PF06513.11 EGC30242.1 - 0.0017 18.0 2.3 0.0017 18.0 2.3 1.3 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.13 EGC30242.1 - 0.003 17.5 0.5 0.77 9.7 0.1 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.16 EGC30242.1 - 0.0031 17.8 0.4 4 7.8 0.0 2.9 2 1 1 3 3 3 1 RNA polymerase Rpb4 MotA_activ PF09114.10 EGC30242.1 - 0.006 16.7 0.1 0.087 13.0 0.0 2.2 2 0 0 2 2 2 1 Transcription factor MotA, activation domain Poly_export PF02563.16 EGC30242.1 - 0.012 15.8 0.1 0.36 11.1 0.0 2.8 2 2 1 3 3 3 0 Polysaccharide biosynthesis/export protein SapB_1 PF05184.15 EGC30242.1 - 0.015 15.3 3.4 0.76 9.9 0.1 3.2 4 0 0 4 4 4 0 Saposin-like type B, region 1 Spore_III_AB PF09548.10 EGC30242.1 - 0.028 14.5 0.5 0.058 13.5 0.5 1.6 1 1 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) RuvA_C PF07499.13 EGC30242.1 - 0.048 14.1 0.3 11 6.6 0.0 3.0 2 1 0 2 2 2 0 RuvA, C-terminal domain SurA_N_2 PF13623.6 EGC30242.1 - 0.053 13.4 1.1 2.1 8.2 0.2 2.2 1 1 1 2 2 2 0 SurA N-terminal domain Fe_hyd_lg_C PF02906.14 EGC30242.1 - 0.081 12.6 0.5 0.21 11.2 0.5 1.7 1 1 0 1 1 1 0 Iron only hydrogenase large subunit, C-terminal domain TetR_C_7 PF14246.6 EGC30242.1 - 0.11 12.6 0.1 6.8 6.8 0.0 2.7 2 1 1 3 3 3 0 AefR-like transcriptional repressor, C-terminal domain D-ser_dehydrat PF14031.6 EGC30243.1 - 5.4e-20 71.9 0.0 1.2e-19 70.8 0.0 1.6 1 0 0 1 1 1 1 Putative serine dehydratase domain Ala_racemase_N PF01168.20 EGC30243.1 - 1.3e-11 44.6 0.0 1.8e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DWNN PF08783.11 EGC30244.1 - 1.6e-25 89.2 0.5 5.9e-25 87.3 0.5 2.1 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.6 EGC30244.1 - 4.5e-08 32.8 8.2 4.5e-08 32.8 8.2 2.1 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC PF00098.23 EGC30244.1 - 2.6 8.3 10.3 0.065 13.3 2.5 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGC30244.1 - 3.3 7.8 7.9 0.2 11.7 1.2 2.3 2 0 0 2 2 2 0 Zinc knuckle Guanylate_kin PF00625.21 EGC30245.1 - 1.8e-55 187.5 0.0 2e-55 187.3 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.6 EGC30245.1 - 8.4e-08 32.8 0.0 3.1e-07 31.0 0.0 1.9 1 1 1 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGC30245.1 - 1.4e-07 31.5 0.0 9.7e-06 25.7 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGC30245.1 - 0.00019 21.6 0.0 0.0016 18.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC30245.1 - 0.00051 20.0 0.0 0.001 19.0 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGC30245.1 - 0.00056 20.4 0.0 0.00072 20.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGC30245.1 - 0.0014 19.0 0.1 0.0023 18.3 0.0 1.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGC30245.1 - 0.0035 17.1 0.1 0.0065 16.2 0.1 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain NTPase_1 PF03266.15 EGC30245.1 - 0.0053 16.7 0.1 0.0086 16.0 0.1 1.6 1 1 0 1 1 1 1 NTPase AAA_22 PF13401.6 EGC30245.1 - 0.0063 16.8 0.0 0.0092 16.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC30245.1 - 0.017 15.2 0.1 0.63 10.0 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ADK PF00406.22 EGC30245.1 - 0.017 15.3 0.1 5.3 7.1 0.0 2.5 2 1 0 2 2 2 0 Adenylate kinase Rad17 PF03215.15 EGC30245.1 - 0.035 14.0 0.0 0.072 13.0 0.0 1.7 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_17 PF13207.6 EGC30245.1 - 0.074 13.5 0.2 0.22 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGC30245.1 - 0.095 13.1 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA PF00004.29 EGC30245.1 - 0.11 13.0 0.0 0.29 11.6 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Methyltransf_12 PF08242.12 EGC30245.1 - 0.12 13.1 0.0 13 6.6 0.0 2.5 1 1 1 2 2 2 0 Methyltransferase domain TBCA PF02970.16 EGC30246.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.5 4 0 0 4 4 4 0 Tubulin binding cofactor A Trehalase PF01204.18 EGC30247.1 - 1.1e-140 469.9 1.0 1.2e-140 469.7 1.0 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.14 EGC30247.1 - 0.0001 21.4 5.0 0.00034 19.7 5.0 1.8 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Pkinase_Tyr PF07714.17 EGC30248.1 - 7.3e-58 195.9 0.0 8.4e-58 195.7 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30248.1 - 3.5e-54 183.9 0.0 4.7e-54 183.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EGC30248.1 - 2e-05 23.8 0.1 4.3e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGC30248.1 - 0.00095 18.6 0.0 0.0014 18.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC30248.1 - 0.0011 18.9 0.1 0.0028 17.6 0.1 1.5 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC30248.1 - 0.0066 15.3 0.3 0.0084 14.9 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC30248.1 - 0.0079 15.5 0.0 0.027 13.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGC30248.1 - 0.024 14.2 0.3 0.043 13.4 0.1 1.5 2 0 0 2 2 2 0 RIO1 family GrlR PF16518.5 EGC30248.1 - 0.1 12.5 0.2 3.3 7.7 0.1 2.3 2 1 0 2 2 2 0 T3SS negative regulator,GrlR zf-UBR PF02207.20 EGC30249.1 - 7.4e-19 67.7 7.1 7.4e-19 67.7 7.1 2.5 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) DUF3439 PF11921.8 EGC30249.1 - 1 9.3 12.7 14 5.7 0.1 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3439) Acyl_transf_1 PF00698.21 EGC30250.1 - 4.7e-19 69.1 0.0 5.1e-19 68.9 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Dicty_spore_N PF04562.12 EGC30251.1 - 2.3e-26 92.8 18.8 2.3e-26 92.8 18.8 5.5 5 1 1 6 6 6 2 Dictyostelium spore coat protein, N terminus FOLN PF09289.10 EGC30251.1 - 0.041 14.1 1.9 0.041 14.1 1.9 10.0 10 1 1 11 11 11 0 Follistatin/Osteonectin-like EGF domain RPN7 PF10602.9 EGC30252.1 - 1.1e-50 171.7 0.3 2.4e-50 170.6 0.3 1.6 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGC30252.1 - 1.2e-17 64.3 0.8 3.6e-17 62.8 0.2 2.1 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.28 EGC30252.1 - 0.0071 16.1 2.0 0.015 15.1 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC30252.1 - 0.013 15.6 2.0 0.064 13.4 0.0 3.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC30252.1 - 0.028 14.6 0.5 0.12 12.7 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC30252.1 - 0.039 14.2 0.0 0.099 12.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC30252.1 - 0.087 12.9 0.0 0.31 11.1 0.0 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat Tnp_22_dsRBD PF17490.2 EGC30252.1 - 0.13 12.3 0.1 0.42 10.7 0.0 1.9 2 0 0 2 2 2 0 L1 transposable element dsRBD-like domain Pneumovirus_M2 PF06436.11 EGC30252.1 - 0.23 11.0 2.7 0.22 11.0 0.6 2.0 2 0 0 2 2 2 0 Pneumovirus matrix protein 2 (M2) Calreticulin PF00262.18 EGC30253.1 - 6.7e-72 242.4 21.0 2.9e-53 181.0 6.3 2.6 2 1 1 3 3 3 2 Calreticulin family AAA_23 PF13476.6 EGC30253.1 - 0.46 11.0 17.5 0.87 10.1 17.5 1.5 1 0 0 1 1 1 0 AAA domain CDC45 PF02724.14 EGC30253.1 - 8.5 4.5 17.2 11 4.1 17.2 1.1 1 0 0 1 1 1 0 CDC45-like protein RlaP PF10127.9 EGC30254.1 - 2.4e-31 109.2 1.6 3.6e-21 75.9 0.1 2.2 2 0 0 2 2 2 2 RNA repair pathway DNA polymerase beta family CBM26 PF16738.5 EGC30254.1 - 0.038 14.2 0.3 0.097 12.9 0.3 1.7 1 0 0 1 1 1 0 Starch-binding module 26 Raptor_N PF14538.6 EGC30254.1 - 0.058 13.3 0.9 0.25 11.3 0.0 2.3 2 0 0 2 2 2 0 Raptor N-terminal CASPase like domain Syntaxin_2 PF14523.6 EGC30254.1 - 2.4 8.6 17.1 4.7 7.6 0.4 3.6 3 1 0 3 3 3 0 Syntaxin-like protein Ras PF00071.22 EGC30255.1 - 1.6e-50 170.9 0.9 2e-50 170.6 0.9 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30255.1 - 2.6e-16 59.9 0.1 5.9e-16 58.8 0.1 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30255.1 - 6.3e-09 35.5 0.1 8.4e-09 35.1 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC30255.1 - 9.4e-08 31.8 0.0 1.4e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGC30255.1 - 8.4e-06 25.3 0.2 1.3e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGC30255.1 - 9.4e-06 25.6 3.8 0.0019 18.1 0.2 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC30255.1 - 3.2e-05 24.0 0.0 6.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC30255.1 - 0.0062 16.1 0.1 0.047 13.2 0.1 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B PRK PF00485.18 EGC30255.1 - 0.023 14.4 0.0 0.031 14.0 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.17 EGC30255.1 - 0.11 12.2 1.1 2.9 7.6 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein PIN_6 PF17146.4 EGC30257.1 - 1.6e-26 92.7 2.2 2.2e-26 92.1 0.0 2.4 3 0 0 3 3 3 1 PIN domain of ribonuclease NOB1_Zn_bind PF08772.11 EGC30257.1 - 1.2e-25 89.4 1.0 1.2e-25 89.4 1.0 1.9 2 0 0 2 2 2 1 Nin one binding (NOB1) Zn-ribbon like Mitofilin PF09731.9 EGC30257.1 - 0.001 18.0 10.8 0.0012 17.8 10.8 1.2 1 0 0 1 1 1 1 Mitochondrial inner membrane protein DNA_RNApol_7kD PF03604.13 EGC30257.1 - 0.072 12.8 1.1 0.17 11.6 1.1 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DUF4411 PF14367.6 EGC30257.1 - 1.2 9.0 9.7 0.71 9.8 3.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF4411) RIX1 PF08167.12 EGC30258.1 - 1e-13 51.5 3.5 1e-13 51.5 3.5 2.2 2 1 0 2 2 2 1 rRNA processing/ribosome biogenesis DUF1840 PF08895.11 EGC30258.1 - 5.7 7.3 10.0 1.7e+02 2.6 8.1 3.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) EF-hand_13 PF17958.1 EGC30259.1 - 2.7e-22 78.4 0.1 1e-21 76.5 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGC30259.1 - 2.3e-15 56.8 1.3 2.3e-15 56.8 1.3 3.4 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EGC30259.1 - 0.9 9.2 9.4 0.24 11.0 0.2 4.1 5 0 0 5 5 5 0 EF hand Na_Ca_ex_C PF16494.5 EGC30261.1 - 0.047 14.1 1.8 1.1 9.7 0.0 2.7 2 0 0 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain Presenilin PF01080.17 EGC30261.1 - 4.9 5.8 10.9 0.73 8.5 6.7 1.6 2 0 0 2 2 2 0 Presenilin Cbl_N2 PF02761.14 EGC30262.1 - 0.012 16.3 0.8 0.092 13.5 0.0 2.6 2 1 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain NT-C2 PF10358.9 EGC30263.1 - 3.8e-23 81.8 8.0 8.6e-23 80.7 8.0 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.19 EGC30263.1 - 6.5e-18 64.9 0.9 1.8e-17 63.5 0.9 1.8 1 0 0 1 1 1 1 DIL domain C2 PF00168.30 EGC30263.1 - 0.0031 17.8 0.2 0.0098 16.2 0.2 1.9 1 0 0 1 1 1 1 C2 domain Ax_dynein_light PF10211.9 EGC30263.1 - 0.0081 16.1 4.5 0.0081 16.1 4.5 4.1 3 1 0 3 3 2 1 Axonemal dynein light chain Glutaredoxin2_C PF04399.13 EGC30263.1 - 0.3 10.9 0.0 0.3 10.9 0.0 3.4 4 0 0 4 4 4 0 Glutaredoxin 2, C terminal domain ATG16 PF08614.11 EGC30263.1 - 1.1 9.5 31.8 0.47 10.6 5.7 3.4 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Noelin-1 PF12308.8 EGC30263.1 - 1.2 9.1 6.5 15 5.6 0.7 3.1 2 0 0 2 2 2 0 Neurogenesis glycoprotein Tho2 PF11262.8 EGC30263.1 - 2.2 7.4 18.1 3.2 6.9 4.2 2.6 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 Cep57_MT_bd PF06657.13 EGC30263.1 - 2.6 8.6 15.9 24 5.5 0.3 4.0 2 1 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 Ntox28 PF15605.6 EGC30263.1 - 3.5 7.9 10.2 1.4 9.2 1.5 3.7 3 1 0 3 3 3 0 Bacterial toxin 28 KASH_CCD PF14662.6 EGC30263.1 - 5.1 6.9 36.4 12 5.7 17.5 3.4 1 1 1 2 2 2 0 Coiled-coil region of CCDC155 or KASH Spc7 PF08317.11 EGC30263.1 - 8 5.2 34.1 0.55 9.1 13.5 2.7 2 1 1 3 3 3 0 Spc7 kinetochore protein Peptidase_C1 PF00112.23 EGC30264.1 - 2e-82 276.5 5.3 2.8e-82 276.1 5.3 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC30264.1 - 1.7e-12 47.6 0.5 3.5e-12 46.6 0.5 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC30264.1 - 0.00062 18.7 0.9 0.081 11.7 0.5 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ABC_membrane_2 PF06472.15 EGC30265.1 - 3e-95 318.7 0.5 3.9e-95 318.3 0.5 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGC30265.1 - 1.5e-17 64.4 0.0 4.5e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGC30265.1 - 0.00027 20.5 0.0 0.048 13.1 0.0 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC30265.1 - 0.00088 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_membrane PF00664.23 EGC30265.1 - 0.0011 18.7 0.9 0.0014 18.3 0.1 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region AAA_21 PF13304.6 EGC30265.1 - 0.0012 18.7 0.0 0.0025 17.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_23 PF13476.6 EGC30265.1 - 0.0012 19.4 0.1 0.0048 17.4 0.0 2.1 3 0 0 3 3 3 1 AAA domain SbmA_BacA PF05992.12 EGC30265.1 - 0.0061 16.0 0.0 0.015 14.8 0.0 1.5 1 1 0 1 1 1 1 SbmA/BacA-like family DUF815 PF05673.13 EGC30265.1 - 0.025 13.7 0.1 0.13 11.4 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_27 PF13514.6 EGC30265.1 - 0.09 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC30265.1 - 0.12 12.9 0.0 0.4 11.2 0.0 1.9 2 0 0 2 2 2 0 AAA domain Sec6 PF06046.13 EGC30265.1 - 0.13 10.6 0.0 0.21 9.9 0.0 1.2 1 0 0 1 1 1 0 Exocyst complex component Sec6 AAA_16 PF13191.6 EGC30265.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Metallophos PF00149.28 EGC30266.1 - 1.7e-13 51.6 1.3 3.9e-13 50.4 1.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SapB_1 PF05184.15 EGC30266.1 - 0.025 14.6 0.4 0.068 13.2 0.4 1.8 1 0 0 1 1 1 0 Saposin-like type B, region 1 Metallophos_2 PF12850.7 EGC30266.1 - 0.13 12.5 0.0 7.5 6.7 0.0 2.4 3 0 0 3 3 3 0 Calcineurin-like phosphoesterase superfamily domain Fn3_assoc PF13287.6 EGC30266.1 - 0.28 11.4 2.5 0.55 10.4 1.1 2.2 2 0 0 2 2 2 0 Fn3 associated GRAM PF02893.20 EGC30267.1 - 2.1e-37 127.5 16.0 8.2e-24 83.7 0.8 5.7 4 2 1 5 5 5 3 GRAM domain Glyco_transf_28 PF03033.20 EGC30267.1 - 7.9e-28 97.2 0.0 2e-27 95.9 0.0 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain FYVE PF01363.21 EGC30267.1 - 2e-13 50.3 9.2 4e-13 49.3 9.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGC30267.1 - 2.5e-12 47.2 0.8 2.5e-12 47.2 0.8 3.5 4 0 0 4 4 3 1 PH domain UDPGT PF00201.18 EGC30267.1 - 4.6e-06 25.7 0.0 1e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGC30267.1 - 0.00032 20.7 0.2 0.0011 19.0 0.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain FYVE_2 PF02318.16 EGC30267.1 - 0.0083 16.3 7.5 0.024 14.8 7.5 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Rtt106 PF08512.12 EGC30267.1 - 0.1 13.0 4.2 4 7.9 0.0 4.0 3 0 0 3 3 3 0 Histone chaperone Rttp106-like SspB PF04386.13 EGC30267.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 0 Stringent starvation protein B IBR PF01485.21 EGC30267.1 - 0.65 10.3 5.1 2 8.7 5.1 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C2HC5 PF06221.13 EGC30267.1 - 7.7 6.6 9.3 7.6 6.6 7.5 1.9 1 1 0 1 1 1 0 Putative zinc finger motif, C2HC5-type Zn-ribbon_8 PF09723.10 EGC30267.1 - 8.2 6.6 7.6 6.2 7.0 1.4 2.4 1 1 1 2 2 2 0 Zinc ribbon domain SMC_Nse1 PF07574.13 EGC30268.1 - 5.4e-17 62.3 3.2 9.1e-12 45.3 1.1 3.0 2 1 1 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex zf-RING-like PF08746.11 EGC30268.1 - 3.8e-05 23.9 7.8 8.7e-05 22.8 7.8 1.6 1 1 0 1 1 1 1 RING-like domain zf-RING_2 PF13639.6 EGC30268.1 - 8.2e-05 22.9 10.4 0.00014 22.2 10.4 1.4 1 0 0 1 1 1 1 Ring finger domain Zn_ribbon_17 PF17120.5 EGC30268.1 - 0.00077 19.0 6.2 0.0013 18.3 6.2 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 EGC30268.1 - 0.0009 19.4 1.9 0.0024 18.1 1.9 1.8 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGC30268.1 - 0.0033 17.6 1.3 0.0033 17.6 1.3 1.7 2 0 0 2 2 2 1 PHD-zinc-finger like domain DUF5506 PF17611.2 EGC30268.1 - 0.007 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Family of unknown function (DUF5506) DUF678 PF05077.12 EGC30268.1 - 0.093 12.9 0.1 0.33 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF678) FANCL_C PF11793.8 EGC30268.1 - 0.11 12.7 9.9 0.79 10.0 9.9 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain BtpA PF03437.15 EGC30268.1 - 0.12 11.8 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 BtpA family PHD PF00628.29 EGC30268.1 - 0.16 11.9 9.4 0.28 11.1 9.4 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.6 EGC30268.1 - 0.16 11.7 8.4 0.36 10.7 8.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4 PF00097.25 EGC30268.1 - 5.3 7.0 10.9 23 4.9 10.9 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.22 EGC30270.1 - 2.5e-08 33.7 0.8 3.8e-08 33.1 0.8 1.3 1 0 0 1 1 1 1 Ras family DUF99 PF01949.16 EGC30270.1 - 0.021 14.2 0.0 0.028 13.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 GATase_5 PF13507.6 EGC30271.1 - 4.2e-98 327.6 0.0 6.4e-98 327.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.22 EGC30271.1 - 4.8e-31 108.0 0.4 1.4e-17 64.3 0.3 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain FGAR-AT_N PF18076.1 EGC30271.1 - 8.6e-20 70.9 0.0 2e-19 69.7 0.0 1.6 1 0 0 1 1 1 1 Formylglycinamide ribonucleotide amidotransferase N-terminal FGAR-AT_linker PF18072.1 EGC30271.1 - 4.9e-10 39.8 0.0 2e-09 37.8 0.0 2.1 2 0 0 2 2 2 1 Formylglycinamide ribonucleotide amidotransferase linker domain AIRS PF00586.24 EGC30271.1 - 0.005 17.5 0.0 0.13 12.9 0.0 3.0 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Exog_C PF18026.1 EGC30272.1 - 0.027 14.5 0.6 0.027 14.5 0.6 1.8 2 0 0 2 2 2 0 Endo/exonuclease (EXOG) C-terminal domain RRM_1 PF00076.22 EGC30273.1 - 2.3e-27 94.6 3.2 3.2e-13 49.3 0.0 3.8 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC30273.1 - 1.1e-10 41.1 0.5 0.00022 20.8 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC30273.1 - 1.1e-06 28.3 0.0 0.065 13.1 0.0 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif DUF4523 PF15023.6 EGC30273.1 - 0.013 15.3 0.0 0.031 14.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) BBS2_N PF14781.6 EGC30273.1 - 0.087 12.7 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 2, N-terminal PHM7_cyt PF14703.6 EGC30273.1 - 0.12 12.6 7.4 2.8 8.1 0.2 3.4 2 2 2 4 4 4 0 Cytosolic domain of 10TM putative phosphate transporter DSPc PF00782.20 EGC30274.1 - 3.9e-25 88.2 0.0 3.9e-25 88.2 0.0 3.4 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 EGC30274.1 - 0.00038 20.3 0.1 0.00095 19.0 0.1 1.6 1 0 0 1 1 1 1 Gelsolin repeat Y_phosphatase PF00102.27 EGC30274.1 - 0.0019 17.8 0.0 0.0019 17.8 0.0 2.7 3 0 0 3 3 3 1 Protein-tyrosine phosphatase CDKN3 PF05706.12 EGC30274.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) zf-B_box PF00643.24 EGC30275.1 - 7.7e-06 26.0 9.9 7.7e-06 26.0 9.9 1.9 2 0 0 2 2 2 1 B-box zinc finger SEC-C PF02810.15 EGC30275.1 - 0.041 13.8 0.1 0.041 13.8 0.1 1.7 2 0 0 2 2 2 0 SEC-C motif Menin PF05053.13 EGC30275.1 - 0.042 12.2 2.8 0.051 12.0 2.8 1.1 1 0 0 1 1 1 0 Menin DUF778 PF05608.12 EGC30275.1 - 3 8.2 6.2 2.1 8.7 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF778) DUF5082 PF16888.5 EGC30277.1 - 0.014 15.6 0.0 0.015 15.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5082) WD40 PF00400.32 EGC30281.1 - 2e-17 63.2 24.0 0.0025 18.6 0.4 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30281.1 - 0.0001 22.5 0.6 1.7 9.0 0.0 4.6 4 1 2 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain SelP_N PF04592.14 EGC30281.1 - 0.0093 15.4 22.8 0.0093 15.4 22.8 2.2 2 1 1 3 3 3 1 Selenoprotein P, N terminal region PIG-F PF06699.11 EGC30282.1 - 1.3e-33 116.7 5.7 2e-33 116.0 5.7 1.3 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F DUF4233 PF14017.6 EGC30282.1 - 7.9 6.9 8.8 35 4.8 5.5 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) Pribosyltran_N PF13793.6 EGC30283.1 - 1.4e-48 163.7 0.8 8e-47 158.0 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGC30283.1 - 1.9e-43 148.6 5.8 7.5e-39 133.6 1.2 3.3 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGC30283.1 - 2e-16 59.9 2.1 2.9e-16 59.4 1.0 1.8 2 0 0 2 2 2 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGC30283.1 - 0.007 15.8 0.2 0.013 15.0 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4461 PF14688.6 EGC30284.1 - 5.3e-31 108.6 0.2 5.8e-29 101.9 0.0 2.1 2 0 0 2 2 2 2 Domain of unknown function (DUF4461) DUF4460 PF14687.6 EGC30284.1 - 6.6e-25 87.3 4.7 6.6e-25 87.3 4.7 3.8 3 1 1 4 4 4 1 Domain of unknown function (DUF4460) RNB PF00773.19 EGC30285.1 - 3.2e-61 207.5 7.6 3.2e-61 207.5 7.6 3.8 3 1 0 3 3 3 1 RNB domain TFIIA PF03153.13 EGC30285.1 - 9.7e-06 25.8 44.6 9.7e-06 25.8 44.6 5.1 3 2 1 4 4 4 1 Transcription factor IIA, alpha/beta subunit RRM_1 PF00076.22 EGC30286.1 - 2.7e-72 238.5 8.3 1.1e-17 63.6 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC30286.1 - 1.8e-06 27.6 0.0 0.076 12.6 0.0 4.3 3 1 1 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC30286.1 - 7.3e-06 26.0 0.2 13 6.0 0.0 6.0 6 0 0 6 6 6 2 RNA recognition motif Nup35_RRM_2 PF14605.6 EGC30286.1 - 3.1e-05 23.9 0.1 0.64 10.1 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Phage_TAC_13 PF16459.5 EGC30286.1 - 0.018 15.5 3.5 0.84 10.1 0.2 4.0 4 0 0 4 4 4 0 Phage tail assembly chaperone, TAC RRM_2 PF04059.12 EGC30286.1 - 0.048 13.9 2.1 1.4 9.2 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif 2 Mrr_cat PF04471.12 EGC30287.1 - 7.8e-08 32.3 0.0 1.7e-07 31.2 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease DUF4090 PF13319.6 EGC30287.1 - 0.0011 19.2 0.0 0.0022 18.2 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) KLRAQ PF10205.9 EGC30288.1 - 2e-30 105.0 12.7 2e-30 105.0 12.7 6.5 5 1 1 6 6 6 2 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.9 EGC30288.1 - 8.8e-13 48.1 6.5 8.8e-13 48.1 6.5 4.2 3 2 2 5 5 5 1 Predicted coiled-coil domain-containing protein DUF1515 PF07439.11 EGC30288.1 - 0.0047 16.9 0.2 0.0047 16.9 0.2 4.4 4 2 2 7 7 7 1 Protein of unknown function (DUF1515) DUF641 PF04859.12 EGC30288.1 - 0.0075 16.6 2.9 0.0075 16.6 2.9 7.2 3 2 2 5 5 5 1 Plant protein of unknown function (DUF641) DUF3287 PF11690.8 EGC30288.1 - 4.4 7.0 11.7 2.5 7.8 0.7 3.6 2 1 0 3 3 3 0 Protein of unknown function (DUF3287) TatD_DNase PF01026.21 EGC30289.1 - 5.6e-38 130.8 0.0 7e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase RACo_linker PF17650.1 EGC30289.1 - 0.056 13.3 0.2 1.6 8.7 0.0 2.5 2 0 0 2 2 2 0 RACo linker region CIMR PF00878.18 EGC30290.1 - 0.0001 22.4 0.6 0.00016 21.7 0.6 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EGC30290.1 - 0.013 14.6 0.0 0.023 13.8 0.0 1.3 1 1 0 1 1 1 0 Mannose-6-phosphate receptor UbiA PF01040.18 EGC30291.1 - 3.1e-14 52.9 9.4 4e-14 52.5 8.9 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Adaptin_N PF01602.20 EGC30292.1 - 5.1e-84 282.7 8.5 2.6e-83 280.4 8.5 1.8 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGC30292.1 - 3.6e-37 127.9 11.1 3e-36 124.9 0.0 4.3 5 0 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGC30292.1 - 1.9e-11 44.0 0.0 7.3e-11 42.2 0.0 2.1 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain DUF3417 PF11897.8 EGC30292.1 - 0.0034 17.8 0.2 0.011 16.2 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF3417) HEAT PF02985.22 EGC30292.1 - 0.0056 16.8 0.2 4.6 7.8 0.0 4.3 5 0 0 5 5 5 1 HEAT repeat HEAT_2 PF13646.6 EGC30292.1 - 0.036 14.5 0.0 0.67 10.4 0.0 2.9 4 0 0 4 4 4 0 HEAT repeats adh_short_C2 PF13561.6 EGC30293.1 - 3.8e-65 219.7 1.1 4.4e-65 219.5 1.1 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGC30293.1 - 8e-53 178.8 5.1 9.2e-53 178.6 5.1 1.0 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGC30293.1 - 1.9e-15 57.2 1.1 2.6e-15 56.8 1.1 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC30293.1 - 2e-07 30.7 1.6 2.1e-06 27.4 1.6 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC30293.1 - 0.00017 20.7 1.5 0.00068 18.7 1.4 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.15 EGC30293.1 - 0.012 15.8 0.3 0.018 15.2 0.3 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.18 EGC30293.1 - 0.012 15.5 1.3 0.02 14.8 1.3 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.19 EGC30293.1 - 0.027 13.8 1.2 0.051 12.9 1.2 1.5 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain CbiA PF01656.23 EGC30293.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.2 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RAMP4 PF06624.12 EGC30297.1 - 0.11 12.6 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 Ribosome associated membrane protein RAMP4 zf-RING_2 PF13639.6 EGC30299.1 - 1e-08 35.3 13.4 1e-08 35.3 13.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC30299.1 - 1.9e-07 30.8 10.7 1.9e-07 30.8 10.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC30299.1 - 3.2e-07 30.1 10.0 7.5e-07 28.9 10.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30299.1 - 6.9e-06 25.8 13.8 6.9e-06 25.8 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC30299.1 - 0.00038 20.7 8.4 0.00038 20.7 8.4 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain DUF572 PF04502.13 EGC30299.1 - 0.00044 20.0 50.4 0.00065 19.4 50.4 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF572) zf-RING_11 PF17123.5 EGC30299.1 - 0.0024 17.6 7.4 0.0057 16.4 7.4 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC30299.1 - 0.0043 16.8 12.9 0.011 15.5 12.9 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGC30299.1 - 0.0083 16.1 10.9 0.0083 16.1 10.9 2.1 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC30299.1 - 0.0099 15.9 10.3 0.0099 15.9 10.3 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGC30299.1 - 0.01 15.9 2.7 0.021 14.9 2.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC30299.1 - 0.011 15.9 12.9 0.011 15.8 10.7 2.4 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC30299.1 - 0.06 13.2 4.3 0.12 12.2 4.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 EGC30299.1 - 1.4 8.6 8.0 2.5 7.8 8.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF5041 PF16444.5 EGC30300.1 - 0.019 15.3 0.0 0.022 15.0 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5041) SecB PF02556.14 EGC30302.1 - 0.013 15.4 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 Preprotein translocase subunit SecB DUF3979 PF13141.6 EGC30302.1 - 0.063 13.5 2.7 0.11 12.8 0.0 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3979) PDZ_1 PF12812.7 EGC30303.1 - 0.029 14.4 0.3 0.11 12.5 0.1 1.8 1 1 1 2 2 2 0 PDZ-like domain AhpC-TSA_2 PF13911.6 EGC30304.1 - 1.2e-21 76.9 0.0 6.2e-21 74.6 0.0 2.0 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.21 EGC30304.1 - 1.8e-06 27.9 0.0 6e-06 26.2 0.0 1.9 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.10 EGC30304.1 - 0.0007 19.3 0.0 0.0021 17.8 0.0 1.8 1 0 0 1 1 1 1 Redoxin Arf PF00025.21 EGC30305.1 - 3.8e-47 160.0 0.0 4.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGC30305.1 - 3.2e-15 56.1 0.0 3.9e-15 55.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30305.1 - 1.1e-12 48.2 0.0 2e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC30305.1 - 2e-12 46.9 0.1 2.4e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC30305.1 - 4.5e-12 45.8 0.1 5.6e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC30305.1 - 2.4e-10 40.5 0.1 5.4e-10 39.4 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGC30305.1 - 3.1e-10 39.7 5.7 3.1e-09 36.5 3.1 2.4 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.27 EGC30305.1 - 4.3e-06 26.4 0.0 3.7e-05 23.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGC30305.1 - 0.0057 16.2 0.6 0.016 14.8 0.6 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.19 EGC30305.1 - 0.013 15.1 0.9 1.2 8.7 0.1 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ArlS_N PF18719.1 EGC30305.1 - 0.063 13.5 0.2 0.063 13.5 0.2 2.4 1 1 1 2 2 2 0 ArlS sensor domain PduV-EutP PF10662.9 EGC30305.1 - 0.12 12.1 0.0 1.6 8.4 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EGC30305.1 - 0.13 12.5 0.1 1.7 8.9 0.1 2.3 1 1 1 2 2 2 0 AAA domain RsbRD_N PF14361.6 EGC30306.1 - 0.046 14.4 6.6 0.35 11.6 0.0 3.8 4 1 0 4 4 4 0 RsbT co-antagonist protein rsbRD N-terminal domain Ribosomal_L36e PF01158.18 EGC30307.1 - 4.6e-29 100.5 4.7 5.1e-29 100.4 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.12 EGC30307.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 1 0 1 1 1 0 DKCLD (NUC011) domain CDP-OH_P_transf PF01066.21 EGC30308.1 - 5.7e-18 65.5 0.1 5.7e-18 65.5 0.1 3.5 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Syja_N PF02383.18 EGC30309.1 - 1e-94 317.5 3.1 1.4e-93 313.8 1.6 2.1 2 0 0 2 2 2 2 SacI homology domain Neur PF00064.18 EGC30309.1 - 0.08 11.7 0.0 0.13 11.0 0.0 1.2 1 0 0 1 1 1 0 Neuraminidase DUF2632 PF10943.8 EGC30309.1 - 0.15 11.6 0.4 0.33 10.5 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2632) PA14 PF07691.12 EGC30310.1 - 3.5e-05 23.6 0.0 6.4e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Thioredoxin PF00085.20 EGC30311.1 - 8.1e-16 57.9 0.0 1.5e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGC30311.1 - 0.039 14.3 0.3 0.43 10.9 0.1 2.5 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_2 PF13098.6 EGC30311.1 - 0.087 13.3 0.3 0.4 11.2 0.0 2.0 2 0 0 2 2 2 0 Thioredoxin-like domain ETRAMP PF09716.10 EGC30311.1 - 0.2 11.7 1.0 1.4 9.0 0.1 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) AAA_23 PF13476.6 EGC30311.1 - 1.7 9.1 9.9 2.5 8.5 9.9 1.3 1 0 0 1 1 1 0 AAA domain DUF4349 PF14257.6 EGC30311.1 - 2.5 7.5 5.2 4.3 6.7 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) Thiolase_N PF00108.23 EGC30312.1 - 2.4e-93 312.3 1.0 3.1e-93 311.9 0.4 1.5 2 0 0 2 2 2 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGC30312.1 - 4e-46 155.7 1.1 1.6e-45 153.7 0.6 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGC30312.1 - 5.9e-07 29.3 1.9 2.2e-06 27.4 0.6 2.5 2 1 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Kelch_1 PF01344.25 EGC30313.1 - 5.7e-39 131.5 17.9 6.1e-08 32.1 0.4 7.1 7 0 0 7 7 6 6 Kelch motif Kelch_6 PF13964.6 EGC30313.1 - 4.5e-37 125.1 9.1 1.2e-05 25.4 0.1 7.1 3 2 4 7 7 7 6 Kelch motif Kelch_4 PF13418.6 EGC30313.1 - 4e-27 94.0 3.1 2.3e-05 24.3 0.0 6.8 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC30313.1 - 3e-17 62.4 0.0 0.0051 17.1 0.0 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC30313.1 - 2.5e-13 49.7 14.7 0.013 15.4 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.15 EGC30313.1 - 1.5e-10 40.6 7.8 0.0016 18.3 0.0 6.0 5 1 1 6 6 6 2 Kelch motif zf-B_box PF00643.24 EGC30313.1 - 1.2e-07 31.8 4.3 1.2e-07 31.8 4.3 2.9 2 1 0 2 2 1 1 B-box zinc finger zf-C3HC4_4 PF15227.6 EGC30313.1 - 0.00047 20.2 13.4 0.00047 20.2 13.4 2.4 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGC30313.1 - 0.0037 17.1 14.8 0.0037 17.1 14.8 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC30313.1 - 0.0038 17.2 12.5 0.0038 17.2 12.5 2.4 2 0 0 2 2 2 1 RING-type zinc-finger 14-3-3 PF00244.20 EGC30313.1 - 0.02 14.4 1.3 0.061 12.8 1.3 1.8 1 0 0 1 1 1 0 14-3-3 protein zf-C3HC4_3 PF13920.6 EGC30313.1 - 0.49 10.3 23.5 0.22 11.4 11.6 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) FYVE PF01363.21 EGC30313.1 - 0.62 10.2 10.1 0.93 9.7 4.5 2.6 2 0 0 2 2 2 0 FYVE zinc finger zf-RING_5 PF14634.6 EGC30313.1 - 0.74 9.8 24.2 3.2 7.8 12.7 2.6 2 0 0 2 2 2 0 zinc-RING finger domain RB_B PF01857.20 EGC30313.1 - 4.5 7.3 7.6 1.1 9.3 3.4 2.2 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain CKS PF01111.19 EGC30314.1 - 8.5e-31 106.0 0.2 1e-30 105.8 0.2 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit UPF0113_N PF17833.1 EGC30315.1 - 1.2e-29 102.7 0.8 1.8e-29 102.1 0.8 1.3 1 0 0 1 1 1 1 UPF0113 Pre-PUA domain UPF0113 PF03657.13 EGC30315.1 - 1.9e-19 69.7 0.0 3e-19 69.0 0.0 1.3 1 0 0 1 1 1 1 UPF0113 PUA domain PUA PF01472.20 EGC30315.1 - 0.012 15.5 0.0 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 PUA domain CLN5 PF15014.6 EGC30316.1 - 4.1e-17 62.8 5.4 6.1e-17 62.2 5.4 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ATG27 PF09451.10 EGC30316.1 - 1.7e-10 41.2 0.1 3.4e-10 40.2 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGC30316.1 - 9.2e-09 34.8 0.0 1.5e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Utp8 PF10395.9 EGC30316.1 - 0.099 11.1 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Utp8 family Med21 PF11221.8 EGC30317.1 - 0.02 15.2 1.0 0.02 15.2 1.0 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Hydrolase_4 PF12146.8 EGC30318.1 - 0.11 11.8 0.0 8.1 5.6 0.0 2.3 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Trp_Tyr_perm PF03222.13 EGC30319.1 - 2.8e-06 26.6 1.3 2.8e-06 26.6 1.3 2.8 3 1 0 3 3 3 1 Tryptophan/tyrosine permease family Tetraspanin PF00335.20 EGC30319.1 - 1.8 8.2 12.4 22 4.7 0.0 3.8 4 0 0 4 4 4 0 Tetraspanin family PA26 PF04636.13 EGC30319.1 - 2 7.3 5.0 4.1 6.2 5.0 1.4 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Dicty_REP PF05086.12 EGC30321.1 - 6.7e-188 626.7 70.1 7.6e-188 626.5 70.1 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein ExsD PF16806.5 EGC30321.1 - 0.39 10.6 6.0 0.048 13.6 0.5 2.1 3 0 0 3 3 3 0 Antiactivator protein ExsD Methyltransf_11 PF08241.12 EGC30324.1 - 2.1e-18 66.8 0.0 3.8e-18 65.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30324.1 - 1.9e-16 60.5 0.0 3.3e-16 59.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC30324.1 - 1.4e-10 41.2 0.0 2.1e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC30324.1 - 2.3e-08 34.7 0.0 4.4e-08 33.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC30324.1 - 7.7e-08 32.4 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC30324.1 - 4e-06 26.4 0.0 8.3e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.15 EGC30324.1 - 5e-06 26.5 0.0 7.9e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGC30324.1 - 0.00035 19.3 0.0 0.00046 18.9 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_15 PF09445.10 EGC30324.1 - 0.00097 18.7 0.0 0.0019 17.8 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase TehB PF03848.14 EGC30324.1 - 0.001 18.5 0.0 0.0018 17.7 0.0 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB PrmA PF06325.13 EGC30324.1 - 0.034 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGC30324.1 - 0.044 13.3 0.0 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain YscJ_FliF PF01514.17 EGC30324.1 - 0.1 12.3 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 Secretory protein of YscJ/FliF family GidB PF02527.15 EGC30324.1 - 0.13 11.6 0.0 0.44 9.8 0.0 1.9 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Pentapeptide_4 PF13599.6 EGC30325.1 - 5.5e-22 77.7 25.1 6.9e-11 42.2 2.4 3.5 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EGC30325.1 - 7.9e-21 73.3 29.0 3.9e-10 39.2 4.5 4.6 2 1 2 4 4 4 4 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 EGC30325.1 - 9.7e-18 64.3 0.0 2.8e-17 62.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 EGC30325.1 - 4.8e-17 61.9 28.8 2.4e-07 30.8 3.0 4.8 1 1 4 5 5 5 5 Pentapeptide repeats (9 copies) BTB PF00651.31 EGC30325.1 - 0.00038 20.7 0.0 0.00095 19.4 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain SUIM_assoc PF16619.5 EGC30325.1 - 0.0011 19.0 3.7 0.0028 17.7 3.7 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 TMEM144 PF07857.12 EGC30325.1 - 0.4 9.6 3.0 0.36 9.8 1.7 1.4 1 1 0 1 1 1 0 Transmembrane family, TMEM144 of transporters DUF908 PF06012.12 EGC30326.1 - 0.051 13.0 0.1 0.052 13.0 0.1 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Glyco_hydro_31 PF01055.26 EGC30327.1 - 4.2e-147 490.9 4.1 5.3e-147 490.6 4.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 NtCtMGAM_N PF16863.5 EGC30327.1 - 6.9e-28 97.2 0.2 1.9e-27 95.8 0.0 1.8 2 0 0 2 2 2 1 N-terminal barrel of NtMGAM and CtMGAM, maltase-glucoamylase Gal_mutarotas_2 PF13802.6 EGC30327.1 - 1.6e-12 47.5 1.4 7.9e-11 42.1 0.3 3.1 2 0 0 2 2 2 1 Galactose mutarotase-like Prenyltrans PF00432.21 EGC30328.1 - 2e-34 117.0 10.0 3.3e-13 49.1 0.1 5.6 5 1 0 5 5 5 4 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGC30328.1 - 0.0022 17.2 0.0 0.17 11.0 0.0 2.5 1 1 2 3 3 3 3 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGC30328.1 - 0.033 13.3 0.0 1 8.4 0.0 2.4 1 1 1 2 2 2 0 Squalene-hopene cyclase N-terminal domain MTTB PF06253.11 EGC30328.1 - 0.056 11.4 0.0 0.08 10.9 0.0 1.1 1 0 0 1 1 1 0 Trimethylamine methyltransferase (MTTB) EamA PF00892.20 EGC30329.1 - 7.5e-12 45.6 29.8 3.7e-08 33.6 8.8 2.3 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGC30329.1 - 1.2e-09 38.0 17.6 1.7e-09 37.5 17.6 1.2 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 EGC30329.1 - 4.5e-05 22.8 17.4 6.5e-05 22.3 17.3 1.4 1 1 0 1 1 1 1 Purine nucleobase transmembrane transport UAA PF08449.11 EGC30329.1 - 0.00049 19.4 15.6 0.0014 17.9 15.6 1.9 1 1 0 1 1 1 1 UAA transporter family zf-TRAF PF02176.18 EGC30330.1 - 2.5e-11 44.1 30.6 1.3e-07 32.2 8.9 4.9 4 1 2 6 6 6 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC30330.1 - 3.1e-05 24.3 32.2 0.0021 18.5 6.0 4.2 1 1 3 4 4 4 3 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC30330.1 - 0.00051 20.3 10.5 0.00051 20.3 10.5 3.7 2 1 2 4 4 4 1 Ring finger domain Tropomyosin_1 PF12718.7 EGC30330.1 - 0.0063 16.7 2.7 0.021 15.0 2.7 1.9 1 0 0 1 1 1 1 Tropomyosin like zf-RING_4 PF14570.6 EGC30330.1 - 0.017 14.9 10.2 0.017 14.9 10.2 4.1 2 1 2 4 4 4 0 RING/Ubox like zinc-binding domain DUF3791 PF12668.7 EGC30330.1 - 0.019 15.0 0.3 0.084 12.9 0.3 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) zf-C2HC_2 PF13913.6 EGC30330.1 - 0.032 14.1 3.5 0.97 9.4 0.2 3.3 2 0 0 2 2 2 0 zinc-finger of a C2HC-type Sina PF03145.16 EGC30330.1 - 0.034 14.1 1.0 0.034 14.1 1.0 4.3 2 1 3 5 5 5 0 Seven in absentia protein family RPAP1_N PF08621.10 EGC30330.1 - 0.75 9.6 4.6 1.6 8.6 4.6 1.5 1 0 0 1 1 1 0 RPAP1-like, N-terminal UQ_con PF00179.26 EGC30331.1 - 3.6e-33 114.2 0.0 4.2e-33 113.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UFC1 PF08694.11 EGC30331.1 - 0.071 12.8 0.0 0.28 10.8 0.0 1.9 1 1 0 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Rotamase PF00639.21 EGC30332.1 - 7.6e-25 87.7 0.0 1.2e-24 87.1 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.6 EGC30332.1 - 1.3e-21 77.3 0.0 2e-21 76.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.26 EGC30332.1 - 6.1e-18 64.9 0.0 1.5e-17 63.7 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC30332.1 - 5.8e-07 29.7 0.0 3.9e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain Rotamase_2 PF13145.6 EGC30332.1 - 6.5e-05 23.8 0.0 0.00033 21.5 0.0 2.0 2 0 0 2 2 2 1 PPIC-type PPIASE domain Pkinase PF00069.25 EGC30333.1 - 1e-81 274.2 0.0 1.2e-81 274.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30333.1 - 1.2e-38 132.9 0.0 1.5e-38 132.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC30333.1 - 7.8e-07 28.7 0.0 2.6e-06 26.9 0.0 1.9 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC30333.1 - 9.5e-07 28.4 0.0 1.4e-06 27.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC30333.1 - 0.00041 19.2 0.0 0.00088 18.1 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGC30333.1 - 0.0058 16.6 0.0 0.021 14.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family FTA2 PF13095.6 EGC30333.1 - 0.013 15.2 0.4 0.89 9.1 0.0 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Antimicrobial_8 PF08103.11 EGC30333.1 - 0.015 15.4 0.4 0.085 13.0 0.1 2.3 2 0 0 2 2 2 0 Uperin family RIO1 PF01163.22 EGC30333.1 - 0.018 14.6 0.9 0.062 12.9 0.9 1.8 1 1 0 1 1 1 0 RIO1 family RasGEF PF00617.19 EGC30334.1 - 3e-57 193.7 0.6 3e-57 193.7 0.6 2.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC30334.1 - 1.5e-27 95.9 0.8 1.5e-27 95.9 0.8 6.3 6 1 0 6 6 6 1 RasGEF N-terminal motif CutA1 PF03091.15 EGC30335.1 - 0.011 15.6 0.1 0.016 15.1 0.1 1.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein HisG_C PF08029.11 EGC30335.1 - 0.13 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain AP_endonuc_2 PF01261.24 EGC30336.1 - 1.9e-32 112.4 0.0 2.4e-32 112.1 0.0 1.1 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel LPD11 PF18824.1 EGC30336.1 - 0.052 13.6 0.1 0.16 12.1 0.1 1.8 1 0 0 1 1 1 0 Large polyvalent protein-associated domain 11 DUF1731 PF08338.11 EGC30338.1 - 7.1e-15 54.6 0.0 1.2e-14 53.8 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.21 EGC30338.1 - 2.4e-13 50.1 0.0 3.1e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC30338.1 - 0.00013 21.5 0.0 0.0022 17.5 0.0 2.3 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGC30338.1 - 0.00023 20.4 0.0 0.00036 19.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGC30338.1 - 0.017 14.3 0.0 0.13 11.4 0.0 2.1 1 1 1 2 2 2 0 Male sterility protein NAD_binding_10 PF13460.6 EGC30338.1 - 0.059 13.3 0.0 0.087 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DapB_N PF01113.20 EGC30338.1 - 0.073 13.2 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EGC30338.1 - 0.092 13.2 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain FNIP PF05725.12 EGC30339.1 - 3.3e-38 129.6 49.8 5.3e-06 26.5 0.5 9.6 2 2 8 11 11 11 11 FNIP Repeat DUF2661 PF10860.8 EGC30339.1 - 0.0054 16.8 8.9 26 5.0 0.1 5.9 4 3 3 7 7 7 3 Protein of unknown function (DUF2661) Cas6b_C PF17262.2 EGC30340.1 - 0.55 10.4 10.0 3.2 7.9 1.4 2.9 2 1 1 3 3 3 0 Cas6b C-terminal domain Ribosomal_L27e PF01777.18 EGC30341.1 - 8.9 6.7 12.7 0.7 10.3 5.8 2.9 3 0 0 3 3 3 0 Ribosomal L27e protein family CDC73_C PF05179.14 EGC30342.1 - 0.02 14.6 1.4 0.022 14.5 0.2 1.6 2 0 0 2 2 2 0 RNA pol II accessory factor, Cdc73 family, C-terminal HVSL PF09749.9 EGC30344.1 - 5.9e-40 137.2 2.5 5.9e-40 137.2 2.5 1.4 2 0 0 2 2 2 1 Uncharacterised conserved protein 2_5_RNA_ligase2 PF13563.6 EGC30344.1 - 0.00095 19.1 0.0 0.0014 18.6 0.0 1.3 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily RNA_pol_Rpc4 PF05132.14 EGC30344.1 - 1.7 9.0 5.8 2 8.8 3.3 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Menin PF05053.13 EGC30344.1 - 7.1 4.9 8.4 10 4.4 8.4 1.2 1 0 0 1 1 1 0 Menin CBM49 PF09478.10 EGC30345.1 - 1.7e-11 44.3 0.6 2.2e-11 43.9 0.6 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 GPR15L PF15854.5 EGC30345.1 - 0.016 15.5 0.1 0.024 14.9 0.1 1.3 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 SWM_repeat PF13753.6 EGC30345.1 - 0.028 14.5 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Putative flagellar system-associated repeat XRCC1_N PF01834.16 EGC30345.1 - 0.075 13.0 0.1 0.098 12.7 0.1 1.1 1 0 0 1 1 1 0 XRCC1 N terminal domain RabGAP-TBC PF00566.18 EGC30346.1 - 1.5e-38 132.6 9.6 1.5e-38 132.6 9.6 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Cyclin_N PF00134.23 EGC30347.1 - 2.4e-15 56.4 0.8 5.9e-15 55.1 0.8 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C_2 PF16899.5 EGC30347.1 - 1.9e-12 47.5 0.6 1.4e-08 35.0 0.0 2.4 2 1 0 2 2 2 2 Cyclin C-terminal domain TFIIB PF00382.19 EGC30347.1 - 0.00013 21.9 0.0 0.00028 20.9 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Pro_isomerase PF00160.21 EGC30348.1 - 4.4e-51 173.3 0.8 2e-50 171.1 0.3 2.1 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.32 EGC30348.1 - 2.1e-07 31.5 0.3 0.00014 22.5 0.1 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30348.1 - 5.8e-05 23.3 0.0 0.054 13.8 0.0 3.2 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain DUF1919 PF08942.10 EGC30348.1 - 0.0062 16.0 0.1 0.014 14.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1919) Kelch_1 PF01344.25 EGC30350.1 - 7.2e-41 137.5 16.7 1.6e-07 30.8 0.1 6.9 6 1 0 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGC30350.1 - 4.9e-39 131.7 6.9 3.7e-08 33.2 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGC30350.1 - 7.4e-39 130.8 11.1 3e-07 30.5 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC30350.1 - 2.8e-36 123.3 13.4 7.8e-08 32.2 0.1 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC30350.1 - 1.3e-34 116.8 9.3 1e-08 34.8 0.5 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC30350.1 - 1.9e-25 88.6 10.9 5.2e-06 26.6 0.0 6.8 6 1 0 6 6 6 5 Galactose oxidase, central domain F-box-like PF12937.7 EGC30350.1 - 1.4e-11 44.1 0.1 2.8e-11 43.1 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC30350.1 - 9.2e-06 25.4 0.1 1.8e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.6 EGC30350.1 - 0.00091 19.6 0.8 21 5.8 0.0 4.6 4 0 0 4 4 4 0 PQQ-like domain Complex1_LYR PF05347.15 EGC30351.1 - 2.6e-10 40.2 0.2 4.1e-10 39.6 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) PAP2_3 PF14378.6 EGC30352.1 - 1.7e-13 50.7 4.0 1.7e-13 50.7 4.0 2.6 3 0 0 3 3 3 2 PAP2 superfamily PAP2 PF01569.21 EGC30352.1 - 1.5e-06 28.0 3.8 1.5e-06 28.0 3.8 2.9 2 1 0 2 2 2 1 PAP2 superfamily Pur_ac_phosph_N PF16656.5 EGC30353.1 - 1.5e-16 60.8 0.5 4.8e-16 59.1 0.5 1.9 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF1816 PF08846.10 EGC30353.1 - 0.018 15.1 0.1 0.93 9.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1816) ETRAMP PF09716.10 EGC30353.1 - 8.2 6.6 7.4 0.89 9.7 2.2 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) TH1 PF04858.13 EGC30354.1 - 9.9e-143 476.8 2.0 1.2e-142 476.6 2.0 1.0 1 0 0 1 1 1 1 TH1 protein FNIP PF05725.12 EGC30355.1 - 3.2e-20 72.0 43.3 8.6e-08 32.2 3.5 10.4 10 1 0 10 10 10 6 FNIP Repeat Aminotran_1_2 PF00155.21 EGC30356.1 - 1.4e-96 323.9 0.0 1.6e-96 323.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.31 EGC30356.1 - 0.012 15.8 0.0 0.087 13.0 0.0 2.3 2 0 0 2 2 2 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC30356.1 - 0.033 14.5 0.1 2.2 8.6 0.0 2.8 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF2043 PF09740.9 EGC30357.1 - 2.7e-27 95.5 1.0 8.8e-27 93.9 0.0 2.4 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2043) Mucin PF01456.17 EGC30357.1 - 0.12 12.4 8.8 0.24 11.4 8.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein AhpC-TSA PF00578.21 EGC30359.1 - 1.9e-43 147.3 0.0 2.2e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC30359.1 - 6.2e-27 94.1 0.0 7.3e-27 93.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EGC30359.1 - 0.00012 22.0 0.1 0.00016 21.6 0.1 1.4 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGC30359.1 - 0.00031 21.0 0.0 0.0005 20.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 EGC30359.1 - 0.033 14.3 0.0 0.043 14.0 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme AAA_22 PF13401.6 EGC30360.1 - 4.8e-05 23.7 0.0 0.00012 22.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGC30360.1 - 0.00096 19.3 0.1 0.014 15.5 0.0 2.7 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) Torsin PF06309.11 EGC30360.1 - 0.0018 18.4 2.7 0.007 16.5 0.2 3.1 3 1 0 3 3 3 1 Torsin AAA_5 PF07728.14 EGC30360.1 - 0.0018 18.3 0.3 0.0075 16.3 0.3 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGC30360.1 - 0.0038 17.6 0.0 0.011 16.2 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PBECR5 PF18814.1 EGC30360.1 - 0.15 12.0 10.0 0.11 12.4 6.2 2.3 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease5 KIP1 PF07765.12 EGC30360.1 - 0.21 11.7 1.5 0.88 9.7 0.2 2.4 2 0 0 2 2 2 0 KIP1-like protein 7TMR-HDED PF07697.11 EGC30360.1 - 0.61 10.2 5.3 1.1 9.3 5.3 1.5 1 0 0 1 1 1 0 7TM-HD extracellular ABC_tran PF00005.27 EGC30360.1 - 2.3 8.7 4.7 1.4 9.4 2.2 2.3 2 1 0 2 2 2 0 ABC transporter DUF1796 PF08795.10 EGC30360.1 - 7.2 6.5 11.9 0.097 12.6 2.3 2.6 3 1 0 3 3 3 0 Putative papain-like cysteine peptidase (DUF1796) SPA PF08616.10 EGC30361.1 - 7.6e-13 48.4 0.2 1.4e-12 47.5 0.2 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGC30361.1 - 5.7e-09 35.1 1.2 5.3e-05 22.1 0.1 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.9 EGC30361.1 - 4.9e-08 32.9 0.5 4.1e-07 29.9 0.2 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.21 EGC30361.1 - 0.057 13.4 0.2 0.14 12.1 0.0 1.7 2 0 0 2 2 2 0 DENN (AEX-3) domain Cortex-I_coil PF09304.10 EGC30361.1 - 0.19 12.0 3.3 0.25 11.6 1.7 2.0 2 0 0 2 2 2 0 Cortexillin I, coiled coil YojJ PF10372.9 EGC30361.1 - 0.21 11.7 2.3 1 9.5 0.9 2.4 1 1 1 2 2 2 0 Bacterial membrane-spanning protein N-terminus RabGAP-TBC PF00566.18 EGC30362.1 - 0.37 10.4 3.2 0.9 9.1 3.1 1.7 1 1 0 1 1 1 0 Rab-GTPase-TBC domain IF4E PF01652.18 EGC30364.1 - 2.4e-52 176.9 3.8 3.6e-52 176.3 3.8 1.3 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Dicty_REP PF05086.12 EGC30364.1 - 0.0026 15.9 4.7 0.003 15.7 4.7 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein CotH PF08757.11 EGC30364.1 - 0.0048 16.5 6.9 0.0061 16.1 6.9 1.2 1 0 0 1 1 1 1 CotH kinase protein Tim54 PF11711.8 EGC30364.1 - 0.0069 15.2 8.4 0.01 14.6 8.4 1.3 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 Folate_carrier PF01770.18 EGC30364.1 - 0.015 14.1 3.1 0.019 13.7 3.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier RNase_H2_suC PF08615.11 EGC30364.1 - 0.075 13.2 3.6 0.14 12.3 3.6 1.5 1 0 0 1 1 1 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SpoIIP PF07454.11 EGC30364.1 - 0.11 12.0 9.0 0.15 11.5 9.0 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Pex14_N PF04695.13 EGC30364.1 - 0.94 10.1 9.8 1.4 9.6 9.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RP-C_C PF11800.8 EGC30364.1 - 1.2 9.2 8.6 1.5 8.9 8.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region FAM176 PF14851.6 EGC30364.1 - 1.3 8.7 7.1 2.7 7.6 7.1 1.6 1 0 0 1 1 1 0 FAM176 family Coilin_N PF15862.5 EGC30364.1 - 1.7 8.5 13.2 4 7.3 13.2 1.6 1 0 0 1 1 1 0 Coilin N-terminus Presenilin PF01080.17 EGC30364.1 - 2 7.1 11.5 2.5 6.8 11.5 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EGC30364.1 - 2 8.8 9.5 3.4 8.1 9.5 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4746 PF15928.5 EGC30364.1 - 4.6 6.6 17.2 7.2 5.9 17.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) MCM_bind PF09739.9 EGC30364.1 - 5.5 5.3 13.8 7.6 4.8 13.8 1.1 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor RR_TM4-6 PF06459.12 EGC30364.1 - 6.4 6.5 15.2 10 5.9 15.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4820 PF16091.5 EGC30364.1 - 7.4 5.9 12.3 13 5.1 12.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) MCM PF00493.23 EGC30365.1 - 1.8e-94 315.0 0.1 1.7e-92 308.6 0.0 3.0 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 EGC30365.1 - 5e-34 116.9 0.1 1e-33 115.8 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC30365.1 - 1.3e-25 89.6 1.8 3.9e-25 88.1 1.8 1.9 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGC30365.1 - 8.2e-09 35.1 0.1 5.7e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI MCM_N PF14551.6 EGC30365.1 - 2.4e-05 24.8 0.5 2.4e-05 24.8 0.5 2.2 2 0 0 2 2 2 1 MCM N-terminal domain AAA_3 PF07726.11 EGC30365.1 - 0.00064 19.6 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC30365.1 - 0.00089 19.0 0.0 0.0021 17.8 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.14 EGC30365.1 - 0.0097 15.9 0.0 0.036 14.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) EphA2_TM PF14575.6 EGC30366.1 - 0.0096 16.8 0.1 0.17 12.8 0.0 2.8 3 0 0 3 3 3 1 Ephrin type-A receptor 2 transmembrane domain DUF2975 PF11188.8 EGC30366.1 - 0.025 14.5 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2975) Cadherin_C_2 PF16492.5 EGC30366.1 - 0.037 14.8 0.3 11 6.8 0.1 2.8 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal Adeno_E3_CR2 PF02439.15 EGC30366.1 - 0.13 12.0 5.5 0.31 10.8 5.5 1.6 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Podoplanin PF05808.11 EGC30366.1 - 0.15 12.1 0.0 0.29 11.2 0.0 1.3 1 0 0 1 1 1 0 Podoplanin PhosphMutase PF10143.9 EGC30367.1 - 1.9e-51 174.4 0.0 2.8e-51 173.8 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.18 EGC30367.1 - 9.5e-27 93.9 0.1 1.2e-26 93.6 0.1 1.0 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.22 EGC30367.1 - 9.3e-05 22.2 0.0 0.0013 18.4 0.0 2.4 2 1 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSP70 PF00012.20 EGC30368.1 - 2.7e-250 831.7 11.7 3.1e-250 831.5 11.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGC30368.1 - 1.3e-16 60.3 0.1 9.3e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein FtsA PF14450.6 EGC30368.1 - 0.0016 18.9 6.4 0.69 10.4 0.3 3.9 3 2 0 3 3 3 1 Cell division protein FtsA Hydantoinase_A PF01968.18 EGC30368.1 - 0.0036 16.6 1.2 0.017 14.4 0.2 2.3 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.16 EGC30368.1 - 0.0089 15.8 0.0 0.024 14.4 0.0 1.7 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.10 EGC30368.1 - 0.035 13.1 0.3 0.53 9.2 0.1 2.3 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain eIF3_N PF09440.10 EGC30368.1 - 7.7 7.0 7.4 4.1 7.9 2.1 2.6 2 1 1 3 3 3 0 eIF3 subunit 6 N terminal domain EGF_2 PF07974.13 EGC30370.1 - 0.00093 19.5 8.3 0.0021 18.4 8.3 1.6 1 0 0 1 1 1 1 EGF-like domain XPA_C PF05181.12 EGC30370.1 - 0.025 14.6 0.0 0.067 13.2 0.0 1.7 1 0 0 1 1 1 0 XPA protein C-terminus Caldesmon PF02029.15 EGC30371.1 - 2.4e-05 23.3 4.9 2.4e-05 23.3 4.9 1.3 2 0 0 2 2 2 1 Caldesmon DDHD PF02862.17 EGC30371.1 - 0.0012 19.0 0.8 0.0013 18.9 0.8 1.2 1 0 0 1 1 1 1 DDHD domain NARP1 PF12569.8 EGC30371.1 - 0.049 12.5 12.0 0.081 11.8 12.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Pox_Ag35 PF03286.14 EGC30371.1 - 0.054 13.3 8.4 0.088 12.6 8.4 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein LNP1 PF15419.6 EGC30371.1 - 0.2 11.9 11.9 0.29 11.4 11.9 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 TLP-20 PF06088.11 EGC30371.1 - 0.21 11.4 9.7 0.35 10.8 9.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Presenilin PF01080.17 EGC30371.1 - 0.27 10.0 4.5 0.36 9.5 4.5 1.2 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGC30371.1 - 0.3 10.8 5.1 0.46 10.2 5.1 1.3 1 0 0 1 1 1 0 Connexin SSURE PF11966.8 EGC30371.1 - 0.46 10.3 4.4 2.1 8.1 0.0 3.1 2 1 0 3 3 3 0 Fibronectin-binding repeat Ureide_permease PF07168.11 EGC30371.1 - 0.5 9.1 1.8 0.85 8.3 1.8 1.3 1 0 0 1 1 1 0 Ureide permease PPL5 PF18168.1 EGC30371.1 - 0.83 8.9 5.8 1.2 8.4 5.8 1.3 1 0 0 1 1 1 0 Prim-pol family 5 Serinc PF03348.15 EGC30371.1 - 0.85 8.5 4.9 1.3 7.9 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) CENP-N PF05238.13 EGC30371.1 - 1 8.6 9.1 1.4 8.1 9.1 1.1 1 0 0 1 1 1 0 Kinetochore protein CHL4 like DUF4770 PF15994.5 EGC30371.1 - 1.1 9.5 9.8 4.1 7.6 2.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) DUF4820 PF16091.5 EGC30371.1 - 1.6 8.0 5.2 2.3 7.5 5.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Ferlin_C PF16165.5 EGC30371.1 - 2.5 8.0 7.6 3.7 7.5 7.6 1.3 1 0 0 1 1 1 0 Ferlin C-terminus GNAT_acetyltr_2 PF13718.6 EGC30371.1 - 4.5 6.6 8.7 8.2 5.8 8.7 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 FAM176 PF14851.6 EGC30371.1 - 9 6.0 11.9 15 5.2 11.9 1.3 1 0 0 1 1 1 0 FAM176 family CDC45 PF02724.14 EGC30371.1 - 9.9 4.3 12.6 15 3.7 12.6 1.2 1 0 0 1 1 1 0 CDC45-like protein WD40 PF00400.32 EGC30372.1 - 4.8e-17 62.0 6.0 3.4e-05 24.5 0.1 6.0 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box PF00646.33 EGC30372.1 - 5.6e-09 35.7 0.4 2.7e-08 33.5 0.4 2.2 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGC30372.1 - 8.9e-09 35.1 0.0 2.8e-08 33.5 0.0 2.0 1 0 0 1 1 1 1 F-box-like START PF01852.19 EGC30372.1 - 3.3e-07 29.9 0.0 0.0038 16.7 0.0 2.6 2 0 0 2 2 2 2 START domain Nup160 PF11715.8 EGC30372.1 - 6e-07 28.5 3.8 0.082 11.5 0.1 3.3 2 1 1 3 3 3 3 Nucleoporin Nup120/160 EGF_2 PF07974.13 EGC30375.1 - 0.00018 21.8 31.0 0.00047 20.5 11.3 3.1 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC30375.1 - 0.08 13.1 22.0 1.4 9.1 7.7 2.8 2 0 0 2 2 2 0 Laminin EGF domain BppU_N PF10651.9 EGC30376.1 - 0.035 13.8 0.5 0.053 13.2 0.5 1.3 1 1 0 1 1 1 0 BppU N-terminal domain CCB1 PF12046.8 EGC30376.1 - 0.092 12.1 0.0 0.097 12.0 0.0 1.1 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B EGF_2 PF07974.13 EGC30377.1 - 7.6e-05 23.0 31.9 0.00035 20.9 11.9 3.1 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC30377.1 - 0.23 11.6 22.7 2.2 8.5 8.8 2.9 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 EGC30378.1 - 0.00016 22.0 31.6 0.00037 20.8 11.9 3.1 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC30378.1 - 0.19 11.9 23.9 0.9 9.7 8.3 2.7 2 0 0 2 2 2 0 Laminin EGF domain EGF_2 PF07974.13 EGC30379.1 - 0.00055 20.3 45.9 0.0012 19.1 10.1 4.3 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.24 EGC30379.1 - 0.99 9.6 36.3 2.8 8.2 7.0 3.9 3 0 0 3 3 3 0 Laminin EGF domain Folliculin_C PF16692.5 EGC30381.1 - 8.8e-72 241.5 0.8 8.8e-72 241.5 0.8 3.0 3 1 0 3 3 3 1 Folliculin C-terminal domain Folliculin PF11704.8 EGC30381.1 - 1.7e-39 135.6 0.4 1.7e-39 135.6 0.4 2.9 2 1 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3439 PF11921.8 EGC30381.1 - 1.3 9.0 8.1 3.6 7.6 8.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LSM PF01423.22 EGC30382.1 - 2e-17 62.6 0.6 3.3e-17 61.9 0.6 1.3 1 0 0 1 1 1 1 LSM domain DBP10CT PF08147.12 EGC30382.1 - 0.023 15.0 0.6 0.038 14.2 0.6 1.4 1 0 0 1 1 1 0 DBP10CT (NUC160) domain UAE_UbL PF14732.6 EGC30382.1 - 0.041 14.5 0.1 0.073 13.7 0.1 1.6 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Hfq PF17209.3 EGC30382.1 - 0.12 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 Hfq protein Cofilin_ADF PF00241.20 EGC30383.1 - 6.5e-18 64.7 0.0 7.2e-18 64.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LIM PF00412.22 EGC30384.1 - 2.4e-11 43.7 7.6 3.2e-11 43.3 7.6 1.2 1 0 0 1 1 1 1 LIM domain zf-C3HC4_2 PF13923.6 EGC30384.1 - 0.013 15.4 4.8 0.084 12.7 0.7 2.5 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF4428 PF14471.6 EGC30384.1 - 0.019 14.8 1.1 0.019 14.8 1.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) Ephrin_rec_like PF07699.13 EGC30384.1 - 0.04 13.7 6.7 0.86 9.4 4.1 2.5 1 1 1 2 2 2 0 Putative ephrin-receptor like TNFR_c6 PF00020.18 EGC30384.1 - 9.3 6.8 13.4 3.1 8.3 3.9 3.1 1 1 2 3 3 3 0 TNFR/NGFR cysteine-rich region TIG PF01833.24 EGC30386.1 - 9.1e-05 22.5 0.2 0.064 13.3 0.2 2.5 2 0 0 2 2 2 2 IPT/TIG domain EGF_2 PF07974.13 EGC30386.1 - 0.021 15.2 14.5 0.021 15.2 14.5 3.3 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.24 EGC30386.1 - 0.25 11.5 0.2 0.25 11.5 0.2 2.7 3 0 0 3 3 3 0 Laminin EGF domain ETRAMP PF09716.10 EGC30387.1 - 0.081 13.0 2.4 8.3 6.6 0.6 3.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) SNARE PF05739.19 EGC30388.1 - 0.00026 20.9 0.1 0.0016 18.4 0.0 2.1 1 1 1 2 2 2 1 SNARE domain APG17 PF04108.12 EGC30388.1 - 0.0014 17.8 1.9 0.0016 17.6 1.9 1.1 1 0 0 1 1 1 1 Autophagy protein Apg17 MscS_porin PF12795.7 EGC30388.1 - 0.018 14.6 3.4 0.022 14.3 3.4 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ApoLp-III PF07464.11 EGC30388.1 - 0.03 14.4 2.2 0.03 14.4 2.2 1.6 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF745 PF05335.13 EGC30388.1 - 0.1 12.3 0.8 0.13 12.0 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) Tropomyosin_1 PF12718.7 EGC30388.1 - 0.37 11.0 4.9 1.9 8.6 4.9 1.9 1 1 0 1 1 1 0 Tropomyosin like Ank_2 PF12796.7 EGC30391.1 - 0.00024 21.6 11.2 0.3 11.7 0.1 5.6 4 2 1 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC30391.1 - 0.037 14.6 5.3 40 5.2 0.0 7.2 6 2 2 8 8 8 0 Ankyrin repeat Sas10_Utp3 PF04000.15 EGC30391.1 - 7.3 7.3 11.9 2.3 8.9 1.6 3.5 3 0 0 3 3 3 0 Sas10/Utp3/C1D family Snurportin1 PF11538.8 EGC30394.1 - 0.012 15.8 6.9 0.039 14.1 6.9 1.9 1 0 0 1 1 1 0 Snurportin1 ubiquitin PF00240.23 EGC30395.1 - 0.0014 18.3 0.1 0.0017 18.1 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGC30395.1 - 0.0034 17.8 0.0 0.0049 17.3 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Dioxygenase_C PF00775.21 EGC30395.1 - 0.086 12.3 0.0 0.096 12.1 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase RhoGEF PF00621.20 EGC30399.1 - 3e-42 144.9 7.0 3e-42 144.9 7.0 3.2 3 1 0 3 3 3 1 RhoGEF domain CH PF00307.31 EGC30399.1 - 7.2e-15 55.1 0.7 2.1e-14 53.6 0.2 2.1 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.11 EGC30399.1 - 0.0005 20.3 0.5 0.0016 18.7 0.1 2.2 2 0 0 2 2 2 1 CDC24 Calponin IQ_SEC7_PH PF16453.5 EGC30399.1 - 0.011 15.8 0.9 0.042 13.8 0.2 2.4 2 0 0 2 2 2 0 PH domain IQ PF00612.27 EGC30399.1 - 0.015 15.0 2.1 0.042 13.6 2.1 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif PH PF00169.29 EGC30399.1 - 0.062 13.8 0.1 0.23 12.0 0.1 2.1 1 0 0 1 1 1 0 PH domain CAMSAP_CH PF11971.8 EGC30399.1 - 0.15 11.9 0.1 0.57 10.1 0.0 2.0 2 0 0 2 2 2 0 CAMSAP CH domain SF3A3 PF16837.5 EGC30399.1 - 0.21 12.1 2.3 2.7 8.5 0.6 3.0 3 0 0 3 3 3 0 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 RRM_1 PF00076.22 EGC30400.1 - 2.8e-17 62.3 0.0 3.3e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC30400.1 - 0.12 12.5 0.1 0.17 12.0 0.1 1.4 1 1 0 1 1 1 0 RNA recognition motif RabGAP-TBC PF00566.18 EGC30401.1 - 4.1e-51 173.7 2.8 4.1e-51 173.7 2.8 4.3 4 1 0 4 4 4 1 Rab-GTPase-TBC domain CHDCT2 PF08074.11 EGC30401.1 - 8.9 6.5 10.2 0.76 9.9 0.6 3.1 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain EF-hand_6 PF13405.6 EGC30402.1 - 3.5e-17 60.8 1.1 6.5e-07 28.8 0.0 3.6 2 1 2 4 4 4 2 EF-hand domain EF-hand_1 PF00036.32 EGC30402.1 - 1.9e-15 55.2 2.4 1.2e-06 27.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGC30402.1 - 4.7e-15 55.8 0.4 3.4e-06 27.4 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC30402.1 - 5.5e-08 32.5 1.5 0.0014 18.4 0.1 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGC30402.1 - 2e-06 28.0 0.1 8.7e-05 22.8 0.0 2.6 1 1 2 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EGC30402.1 - 0.00058 19.2 0.2 0.00058 19.2 0.2 2.9 3 1 0 3 3 3 1 EF hand DUF3349 PF11829.8 EGC30402.1 - 0.0024 18.6 0.1 2.5 8.9 0.0 2.3 2 1 0 2 2 2 2 Protein of unknown function (DUF3349) DUF2666 PF10869.8 EGC30402.1 - 0.0071 16.6 0.3 0.073 13.3 0.1 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF2666) CortBP2 PF09727.9 EGC30402.1 - 0.0082 16.1 0.2 0.01 15.7 0.2 1.1 1 0 0 1 1 1 1 Cortactin-binding protein-2 Orthopox_B11R PF07033.11 EGC30402.1 - 0.011 15.5 0.5 0.011 15.5 0.5 2.3 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Poly_export PF02563.16 EGC30402.1 - 0.016 15.4 0.2 0.24 11.7 0.1 2.3 2 1 0 2 2 2 0 Polysaccharide biosynthesis/export protein EF-hand_4 PF12763.7 EGC30402.1 - 0.028 14.4 0.3 8.3 6.4 0.1 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand SesA PF17107.5 EGC30402.1 - 0.03 14.5 0.2 0.072 13.3 0.2 1.6 1 1 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases His_kinase PF06580.13 EGC30402.1 - 0.039 14.3 0.1 0.064 13.6 0.1 1.4 1 0 0 1 1 1 0 Histidine kinase EFhand_Ca_insen PF08726.10 EGC30402.1 - 0.042 13.9 0.1 0.38 10.9 0.0 2.1 2 0 0 2 2 2 0 Ca2+ insensitive EF hand Death PF00531.22 EGC30402.1 - 0.095 12.9 0.0 0.25 11.5 0.0 1.8 1 1 1 2 2 2 0 Death domain zf-CCHC_5 PF14787.6 EGC30402.1 - 0.1 12.3 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger Bap31_Bap29_C PF18035.1 EGC30402.1 - 0.13 12.3 0.6 0.67 10.0 0.1 2.1 2 0 0 2 2 2 0 Bap31/Bap29 cytoplasmic coiled-coil domain Caleosin PF05042.13 EGC30402.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.7 1 1 0 1 1 1 0 Caleosin related protein Steroid_dh PF02544.16 EGC30403.1 - 1.1e-24 87.1 7.1 1.1e-24 87.1 7.1 2.5 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGC30403.1 - 0.03 14.7 0.2 0.03 14.7 0.2 3.0 3 0 0 3 3 3 0 Phospholipid methyltransferase MFS_1 PF07690.16 EGC30403.1 - 3.2 6.6 8.0 0.57 9.0 1.4 2.3 2 1 0 2 2 2 0 Major Facilitator Superfamily MOSC_N PF03476.16 EGC30404.1 - 5e-19 68.4 0.0 8.3e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EGC30404.1 - 5.3e-16 58.8 0.0 8.5e-16 58.2 0.0 1.3 1 0 0 1 1 1 1 MOSC domain UQ_con PF00179.26 EGC30405.1 - 1.3e-23 83.2 0.3 2.1e-23 82.5 0.3 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme AMP-binding PF00501.28 EGC30406.1 - 5.1e-76 256.0 0.0 6.5e-76 255.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC30406.1 - 8.6e-11 42.7 0.0 1.9e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC30406.1 - 6.2e-10 38.8 3.1 1.3e-09 37.8 3.1 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus ETF PF01012.21 EGC30407.1 - 6.8e-49 166.2 0.8 9.2e-49 165.8 0.8 1.1 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPT PF03151.16 EGC30408.1 - 5.8e-19 68.5 30.2 6.7e-19 68.3 30.2 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGC30408.1 - 2.5e-09 37.4 32.1 1.8e-06 28.2 13.1 2.0 2 0 0 2 2 2 2 EamA-like transporter family DUF3430 PF11912.8 EGC30409.1 - 1.4e-17 64.4 32.8 1.8e-17 64.1 32.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC30409.1 - 0.085 13.1 10.8 0.45 10.8 2.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) Ras PF00071.22 EGC30410.1 - 7.6e-55 184.9 0.0 8.8e-55 184.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30410.1 - 6.5e-22 78.0 0.0 9.5e-22 77.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30410.1 - 2.2e-09 37.0 0.0 2.7e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC30410.1 - 0.00029 20.4 0.0 0.0013 18.4 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.22 EGC30411.1 - 1.1e-44 150.0 1.1 5.4e-20 71.0 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC30411.1 - 1.6e-08 34.2 0.3 0.00013 21.5 0.0 3.1 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC30411.1 - 2e-05 24.6 0.0 0.032 14.3 0.0 3.1 3 0 0 3 3 3 1 RNA binding motif Limkain-b1 PF11608.8 EGC30411.1 - 0.0092 16.0 0.0 1.3 9.1 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 EGC30411.1 - 0.014 15.5 0.0 0.7 10.1 0.0 2.8 2 0 0 2 2 2 0 RNA recognition motif Rad9 PF04139.13 EGC30412.1 - 0.028 13.9 0.1 0.03 13.8 0.1 1.0 1 0 0 1 1 1 0 Rad9 Bacillus_PapR PF05968.11 EGC30413.1 - 0.71 9.8 4.1 0.39 10.6 0.9 2.3 2 0 0 2 2 2 0 Bacillus PapR protein Med23 PF11573.8 EGC30414.1 - 1.6e-45 155.3 26.8 2.7e-45 154.6 26.8 1.2 1 0 0 1 1 1 1 Mediator complex subunit 23 Patched PF02460.18 EGC30415.1 - 4.4e-94 316.2 10.9 4.4e-94 316.2 10.9 1.4 1 1 1 2 2 2 1 Patched family Sterol-sensing PF12349.8 EGC30415.1 - 4.6e-49 166.2 5.2 4.6e-49 166.2 5.2 3.4 3 1 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EGC30415.1 - 1.3e-20 74.0 12.9 4e-20 72.4 12.9 1.7 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 EGC30415.1 - 0.58 7.7 17.9 0.94 7.0 17.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.15 EGC30415.1 - 1.7 7.5 29.6 0.69 8.8 8.1 2.7 2 0 0 2 2 2 0 MMPL family Pkinase PF00069.25 EGC30416.1 - 6.4e-67 225.7 0.0 8.5e-67 225.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30416.1 - 1.3e-49 168.9 0.0 1.8e-49 168.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC30416.1 - 2e-05 23.7 0.7 2.9e-05 23.2 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC30416.1 - 0.00023 20.6 0.0 0.0023 17.3 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGC30416.1 - 0.00037 19.4 0.0 0.00069 18.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase FAM176 PF14851.6 EGC30416.1 - 0.054 13.2 7.4 0.73 9.5 1.1 2.3 2 0 0 2 2 2 0 FAM176 family DUF573 PF04504.14 EGC30416.1 - 0.059 14.0 0.1 0.18 12.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Phage_Gp23 PF10669.9 EGC30416.1 - 0.2 12.0 2.6 0.47 10.8 2.6 1.6 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) RXT2_N PF08595.11 EGC30416.1 - 0.35 10.9 7.3 1.1 9.2 2.7 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 EGC30416.1 - 0.43 10.8 11.7 2.6 8.3 3.9 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 EGC30416.1 - 8.4 6.8 12.1 28 5.2 8.0 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Kelch_4 PF13418.6 EGC30417.1 - 0.17 11.9 0.6 1.1 9.3 0.0 2.1 2 0 0 2 2 2 0 Galactose oxidase, central domain FmiP_Thoc5 PF09766.9 EGC30418.1 - 3.7e-89 299.5 7.9 3.7e-89 299.5 7.9 2.2 2 0 0 2 2 2 1 Fms-interacting protein/Thoc5 Morc6_S5 PF17942.1 EGC30418.1 - 0.0038 17.3 0.2 0.39 10.8 0.2 2.8 2 0 0 2 2 2 1 Morc6 ribosomal protein S5 domain 2-like UEV PF05743.13 EGC30418.1 - 0.0069 16.2 0.2 0.022 14.6 0.1 1.8 2 0 0 2 2 2 1 UEV domain RestrictionSfiI PF11487.8 EGC30418.1 - 0.018 14.9 0.2 0.037 13.9 0.2 1.4 1 0 0 1 1 1 0 Type II restriction enzyme SfiI RWD PF05773.22 EGC30418.1 - 0.4 11.0 9.5 0.038 14.3 3.5 2.6 2 1 0 2 2 2 0 RWD domain MFS_1 PF07690.16 EGC30419.1 - 1.3e-10 40.8 18.6 1.6e-10 40.4 18.6 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC30419.1 - 0.033 13.0 17.0 0.17 10.7 16.3 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter AA_permease_2 PF13520.6 EGC30420.1 - 0.0076 15.1 2.3 0.0097 14.8 2.3 1.1 1 0 0 1 1 1 1 Amino acid permease 7tm_3 PF00003.22 EGC30420.1 - 0.02 14.6 3.7 0.025 14.3 3.7 1.1 1 0 0 1 1 1 0 7 transmembrane sweet-taste receptor of 3 GCPR CCDC53 PF10152.9 EGC30420.1 - 0.49 10.8 10.1 0.083 13.3 5.8 1.7 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex Kinesin PF00225.23 EGC30421.1 - 1.2e-13 50.7 0.2 1.3e-13 50.6 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain LuxT_C PF18285.1 EGC30421.1 - 0.012 16.1 0.5 0.022 15.3 0.5 1.5 1 1 0 1 1 1 0 Tetracycline repressor LuxT C-terminal domain DUF3767 PF12597.8 EGC30422.1 - 2.4e-09 36.9 0.0 3.4e-09 36.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) Ins134_P3_kin_N PF17927.1 EGC30423.1 - 0.32 11.4 2.3 0.92 10.0 0.3 2.8 3 0 0 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Arf PF00025.21 EGC30424.1 - 6e-66 221.2 0.1 7.4e-66 220.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGC30424.1 - 3.3e-14 52.8 0.0 4.1e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30424.1 - 8.9e-13 48.5 0.0 1.2e-12 48.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC30424.1 - 5.1e-12 45.6 0.0 6.2e-12 45.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC30424.1 - 1.2e-10 41.1 1.6 1.6e-07 30.8 0.2 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC30424.1 - 1.7e-07 30.9 0.0 2.1e-07 30.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC30424.1 - 0.00048 20.2 0.0 0.00071 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Me-amine-dh_H PF06433.11 EGC30424.1 - 0.022 13.7 0.0 0.028 13.3 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) MeaB PF03308.16 EGC30424.1 - 0.033 13.2 0.0 0.4 9.6 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB SRP54 PF00448.22 EGC30424.1 - 0.052 13.2 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain ABC_tran PF00005.27 EGC30424.1 - 0.16 12.5 0.7 0.39 11.2 0.7 1.8 1 1 0 1 1 1 0 ABC transporter AMP-binding PF00501.28 EGC30425.1 - 1.2e-63 215.2 0.0 1.7e-63 214.7 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.12 EGC30425.1 - 3e-47 160.9 0.0 5.3e-47 160.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein PP-binding PF00550.25 EGC30425.1 - 5e-05 23.6 0.3 0.00011 22.5 0.3 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site ZZ PF00569.17 EGC30425.1 - 6.5e-05 22.7 10.1 0.00013 21.7 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type 3Beta_HSD PF01073.19 EGC30425.1 - 8.1e-05 21.8 0.8 0.12 11.3 0.0 2.7 2 0 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC30425.1 - 0.00011 21.8 0.3 0.00031 20.3 0.0 1.9 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family RnlB_antitoxin PF15933.5 EGC30425.1 - 1.6 9.1 7.7 0.6 10.4 0.1 3.9 3 0 0 3 3 3 0 Antitoxin to bacterial toxin RNase LS or RnlA DUF2805 PF10985.8 EGC30426.1 - 0.42 11.0 3.6 1.5 9.3 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2805) TFIIA PF03153.13 EGC30427.1 - 0.00067 19.8 19.6 0.00086 19.4 19.6 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 EGC30427.1 - 0.11 10.4 16.2 0.13 10.1 16.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF2722 PF10846.8 EGC30427.1 - 0.17 10.8 25.7 0.27 10.1 25.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) TERB2 PF15101.6 EGC30427.1 - 0.26 11.3 12.8 0.42 10.6 12.8 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pex14_N PF04695.13 EGC30427.1 - 0.32 11.6 17.1 0.54 10.9 17.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Presenilin PF01080.17 EGC30427.1 - 0.43 9.3 10.9 0.82 8.4 10.9 1.5 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGC30427.1 - 2 8.4 6.7 0.096 12.7 1.5 1.5 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S49_N PF08496.10 EGC30427.1 - 2.2 8.3 11.3 4.8 7.2 11.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4407 PF14362.6 EGC30427.1 - 2.9 7.2 9.2 4.9 6.4 9.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Roughex PF06020.11 EGC30427.1 - 3.1 6.8 12.2 4.6 6.2 12.2 1.2 1 0 0 1 1 1 0 Drosophila roughex protein CobT PF06213.12 EGC30427.1 - 3.9 6.8 13.5 5.8 6.2 13.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MAS20 PF02064.15 EGC30427.1 - 4.2 7.5 14.6 9.9 6.3 14.6 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor UPF0524 PF15823.5 EGC30427.1 - 5.2 6.4 8.0 2.1 7.7 3.8 2.0 2 0 0 2 2 2 0 UPF0524 of C3orf70 UPF0560 PF10577.9 EGC30427.1 - 5.5 5.4 15.6 7.4 4.9 15.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Band_3_cyto PF07565.13 EGC30427.1 - 6.6 6.4 19.5 50 3.6 0.0 2.3 1 1 1 2 2 2 0 Band 3 cytoplasmic domain Exonuc_VII_L PF02601.15 EGC30427.1 - 7.3 6.1 13.8 11 5.5 13.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit mRNA_cap_enzyme PF01331.19 EGC30428.1 - 1.3e-33 116.5 1.8 2.7e-33 115.5 1.8 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_cap_C PF03919.15 EGC30428.1 - 2.8e-12 47.2 1.5 1.2e-11 45.2 0.8 2.3 2 0 0 2 2 2 1 mRNA capping enzyme, C-terminal domain mRNA_triPase PF02940.15 EGC30428.1 - 9.5e-09 35.3 4.5 7.6e-08 32.3 4.5 2.4 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain DNA_ligase_A_M PF01068.21 EGC30428.1 - 0.00024 20.8 0.8 0.35 10.5 0.1 2.7 1 1 1 2 2 2 2 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.9 EGC30428.1 - 0.00072 18.5 2.7 0.0013 17.7 2.7 1.4 1 0 0 1 1 1 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase Rho_N PF07498.12 EGC30429.1 - 0.00043 20.1 0.5 0.0011 18.9 0.5 1.7 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain MFS_1 PF07690.16 EGC30430.1 - 2.9e-30 105.4 56.3 2.4e-23 82.7 37.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC30430.1 - 8.7e-07 28.2 5.5 8.7e-07 28.2 5.5 3.2 1 1 2 3 3 3 2 Sugar (and other) transporter DUF4870 PF09685.10 EGC30430.1 - 0.12 12.4 0.1 0.12 12.4 0.1 4.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4870) FYVE PF01363.21 EGC30431.1 - 0.0073 16.4 7.7 0.2 11.8 1.1 3.0 1 1 0 2 2 2 2 FYVE zinc finger PhnA_Zn_Ribbon PF08274.12 EGC30431.1 - 0.019 14.9 6.5 2.4 8.2 2.2 2.6 2 0 0 2 2 2 0 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.7 EGC30431.1 - 0.25 11.4 21.5 0.45 10.5 4.6 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain PADR1 PF08063.12 EGC30431.1 - 0.39 10.5 10.6 1.2 9.0 3.7 2.5 2 0 0 2 2 2 0 PADR1 (NUC008) domain zf-Dof PF02701.15 EGC30431.1 - 1.9 8.7 20.2 3.5 7.9 6.1 3.4 2 2 0 2 2 2 0 Dof domain, zinc finger DZR PF12773.7 EGC30431.1 - 2.3 8.3 9.3 3.5 7.7 2.7 2.7 2 0 0 2 2 2 0 Double zinc ribbon Mitofilin PF09731.9 EGC30431.1 - 3.5 6.4 28.3 5.2 5.8 28.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein HORMA PF02301.18 EGC30432.1 - 8e-11 41.9 0.4 8e-11 41.9 0.4 2.9 1 1 0 2 2 2 1 HORMA domain SM-ATX PF14438.6 EGC30432.1 - 2.2 8.5 4.7 9.8 6.4 0.7 2.6 2 0 0 2 2 2 0 Ataxin 2 SM domain Pkinase_Tyr PF07714.17 EGC30433.1 - 9.5e-63 211.9 0.0 1.9e-62 210.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30433.1 - 1.4e-57 195.1 0.6 1.2e-56 192.0 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain MORN PF02493.20 EGC30433.1 - 0.00035 20.3 3.0 0.65 10.0 0.6 3.4 3 0 0 3 3 3 2 MORN repeat APH PF01636.23 EGC30433.1 - 0.015 15.2 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC30433.1 - 0.032 13.6 0.0 0.086 12.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family CPBP PF02517.16 EGC30434.1 - 1.5e-06 28.5 11.4 1.5e-06 28.5 11.4 2.6 2 1 1 3 3 3 1 CPBP intramembrane metalloprotease DUF3188 PF11384.8 EGC30434.1 - 0.044 13.5 0.3 0.12 12.1 0.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Tma16 PF11176.8 EGC30435.1 - 4.5e-24 85.0 4.8 1.3e-12 47.8 2.9 2.1 1 1 1 2 2 2 2 Translation machinery-associated protein 16 Minor_capsid_1 PF10665.9 EGC30435.1 - 0.0022 18.1 0.2 0.004 17.3 0.2 1.4 1 0 0 1 1 1 1 Minor capsid protein Ribosomal_L28e PF01778.17 EGC30436.1 - 2.8e-27 95.7 4.2 3.5e-27 95.4 4.2 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family CBM49 PF09478.10 EGC30437.1 - 1.4e-16 60.6 0.0 1.8e-16 60.2 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 bZIP_1 PF00170.21 EGC30439.1 - 6e-14 51.9 10.1 1.9e-13 50.3 10.1 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGC30439.1 - 2.5e-06 27.5 8.5 2.5e-06 27.5 8.5 3.2 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGC30439.1 - 1.6e-05 25.3 9.0 1.6e-05 25.3 9.0 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor RasGEF PF00617.19 EGC30440.1 - 3.3e-51 174.0 0.2 3.3e-51 174.0 0.2 2.7 3 0 0 3 3 3 1 RasGEF domain RCC1 PF00415.18 EGC30440.1 - 1.1e-45 154.0 8.6 2.7e-11 43.9 0.0 7.6 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC30440.1 - 1.1e-30 104.8 16.5 3.5e-10 39.4 0.4 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.20 EGC30440.1 - 7.5e-19 68.7 1.4 9.3e-17 61.9 0.5 3.2 2 0 0 2 2 2 1 RhoGEF domain RasGEF_N PF00618.20 EGC30440.1 - 2.5e-17 63.0 1.7 2.5e-17 63.0 1.7 4.4 3 1 1 4 4 4 1 RasGEF N-terminal motif DUF948 PF06103.11 EGC30440.1 - 0.018 15.3 0.1 5.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Hira PF07569.11 EGC30440.1 - 0.15 11.8 0.0 0.15 11.8 0.0 4.4 4 1 0 4 4 4 0 TUP1-like enhancer of split Trypan_PARP PF05887.11 EGC30440.1 - 9.3 6.2 7.8 21 5.1 7.8 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) WD40 PF00400.32 EGC30441.1 - 6.6e-32 109.0 15.0 1.1e-05 26.1 0.1 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30441.1 - 1.5e-15 57.3 1.0 0.044 14.1 0.0 6.1 1 1 5 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC30441.1 - 1.7e-06 27.6 2.3 5.7e-05 22.6 1.9 3.0 1 1 1 2 2 2 1 WD40-like domain Frtz PF11768.8 EGC30441.1 - 6.6e-05 21.4 0.1 0.012 13.9 0.0 2.7 1 1 1 3 3 3 2 WD repeat-containing and planar cell polarity effector protein Fritz PHTB1_N PF14727.6 EGC30441.1 - 0.0003 20.3 0.7 2.9 7.1 0.0 3.6 1 1 3 4 4 4 2 PTHB1 N-terminus eIF2A PF08662.11 EGC30441.1 - 0.00044 20.2 0.0 0.61 9.9 0.0 2.9 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 EGC30441.1 - 0.0032 17.3 0.2 19 5.4 0.0 3.9 4 0 0 4 4 4 0 PQQ enzyme repeat DUF5114 PF17141.4 EGC30441.1 - 0.028 14.9 0.0 0.1 13.2 0.0 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF5114) Kelch_6 PF13964.6 EGC30441.1 - 0.04 14.2 0.3 2.3 8.6 0.0 3.5 4 0 0 4 4 4 0 Kelch motif Nbas_N PF15492.6 EGC30441.1 - 0.06 12.7 0.1 3.5 6.9 0.0 3.0 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal PQQ_2 PF13360.6 EGC30441.1 - 0.066 12.8 0.0 0.17 11.4 0.0 1.7 1 1 0 1 1 1 0 PQQ-like domain Ras PF00071.22 EGC30442.1 - 1e-20 73.9 0.6 1.5e-20 73.4 0.6 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30442.1 - 7.4e-11 42.3 0.4 1.7e-10 41.2 0.4 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30442.1 - 1.1e-07 31.4 0.3 1.8e-07 30.8 0.3 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC30442.1 - 0.00069 19.7 0.8 0.0014 18.7 0.8 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGC30442.1 - 0.0082 15.9 0.1 0.016 14.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGC30442.1 - 0.21 11.6 4.4 0.1 12.6 1.5 1.9 1 1 0 2 2 2 0 AAA domain TnsE_C PF18623.1 EGC30443.1 - 0.07 13.0 0.5 3.2 7.7 0.0 2.0 2 0 0 2 2 2 0 TnsE C-terminal domain Herpes_capsid PF06112.11 EGC30443.1 - 1.2 9.2 7.5 1.3 9.1 7.5 1.1 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein PIP5K PF01504.18 EGC30444.1 - 8e-65 218.8 2.6 9.7e-65 218.5 2.6 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.23 EGC30445.1 - 1.6e-59 201.6 2.7 6.4e-38 130.5 0.0 2.9 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGC30445.1 - 1.2e-21 77.2 0.0 2.7e-21 76.1 0.0 1.7 1 1 0 1 1 1 1 Microtubule binding DUF5094 PF17015.5 EGC30445.1 - 8 6.5 12.0 0.17 12.0 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5094) BRCT PF00533.26 EGC30447.1 - 4.5e-11 43.0 3.3 1.2e-10 41.6 1.3 2.7 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC30447.1 - 6.7e-09 36.0 0.7 2.8e-08 34.0 0.3 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain SF1-HH PF16275.5 EGC30447.1 - 0.0021 18.3 0.5 0.0021 18.3 0.5 2.4 2 1 0 2 2 2 1 Splicing factor 1 helix-hairpin domain PTCB-BRCT PF12738.7 EGC30447.1 - 0.02 14.8 0.2 0.046 13.7 0.2 1.6 1 0 0 1 1 1 0 twin BRCT domain DUF3019 PF11456.8 EGC30447.1 - 1.9 9.0 4.7 0.98 10.0 0.1 2.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3019) Cep57_CLD_2 PF14197.6 EGC30447.1 - 2.2 8.4 14.5 2.3 8.3 4.8 3.3 2 1 0 2 2 2 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.21 EGC30447.1 - 3.7 7.7 15.6 1.7 8.8 1.0 3.4 3 0 0 3 3 3 0 bZIP transcription factor TetR_C_17 PF17922.1 EGC30448.1 - 0.06 13.4 0.1 0.18 11.9 0.1 1.8 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain UPF0542 PF15086.6 EGC30449.1 - 0.0086 16.0 0.1 0.017 15.0 0.1 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 Androgen_recep PF02166.16 EGC30449.1 - 0.009 14.9 4.8 0.015 14.2 4.8 1.3 1 0 0 1 1 1 1 Androgen receptor DUF1118 PF06549.12 EGC30449.1 - 0.036 14.4 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1118) Metallophos_C PF14008.6 EGC30449.1 - 0.083 13.8 3.0 0.12 13.3 1.0 2.4 2 0 0 2 2 2 0 Iron/zinc purple acid phosphatase-like protein C PEX11 PF05648.14 EGC30449.1 - 0.24 10.8 1.3 0.45 9.9 1.3 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) DUF3169 PF11368.8 EGC30449.1 - 0.28 10.7 1.3 0.48 9.9 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Mem_trans PF03547.18 EGC30449.1 - 0.5 8.7 13.0 0.15 10.4 7.7 2.1 2 0 0 2 2 2 0 Membrane transport protein Ndc1_Nup PF09531.10 EGC30449.1 - 0.78 8.4 9.9 1.2 7.7 9.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CNOT11 PF10155.9 EGC30450.1 - 0.015 15.4 1.2 0.13 12.4 0.0 2.4 2 0 0 2 2 2 0 CCR4-NOT transcription complex subunit 11 Pkinase_Tyr PF07714.17 EGC30451.1 - 1e-46 159.4 0.0 3.4e-30 105.2 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGC30451.1 - 1.9e-46 158.6 0.0 1.9e-45 155.3 0.0 2.7 2 1 0 2 2 2 1 Protein kinase domain RhoGEF PF00621.20 EGC30451.1 - 8.6e-19 68.5 11.8 8.6e-19 68.5 11.8 4.0 4 0 0 4 4 4 1 RhoGEF domain IQ PF00612.27 EGC30451.1 - 0.0008 19.0 2.1 0.0027 17.4 2.1 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Kdo PF06293.14 EGC30451.1 - 0.0012 18.2 0.0 0.0032 16.9 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC30451.1 - 0.13 12.1 0.0 0.45 10.4 0.0 1.7 1 1 0 1 1 1 0 Phosphotransferase enzyme family His_Phos_1 PF00300.22 EGC30452.1 - 5.3e-08 32.8 0.1 0.0044 16.7 0.1 2.1 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) FNIP PF05725.12 EGC30453.1 - 3.3e-57 190.4 76.3 3.1e-15 56.1 0.9 10.0 7 3 2 10 10 10 9 FNIP Repeat FNIP PF05725.12 EGC30454.1 - 1.3e-65 217.3 61.1 3e-13 49.7 1.7 11.3 8 4 3 11 11 11 11 FNIP Repeat adh_short PF00106.25 EGC30455.1 - 9e-09 35.1 0.0 2.5e-08 33.6 0.0 1.7 2 0 0 2 2 2 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC30455.1 - 0.0002 21.0 0.0 0.00099 18.7 0.0 1.9 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC30455.1 - 0.017 15.1 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 KR domain CCD PF07860.11 EGC30455.1 - 0.095 12.7 1.0 0.33 11.0 1.0 1.9 1 0 0 1 1 1 0 WisP family C-Terminal Region Coiled PF05710.12 EGC30456.1 - 2.9e-19 69.7 14.6 3.3e-19 69.5 14.6 1.0 1 0 0 1 1 1 1 Coiled coil Methyltransf_16 PF10294.9 EGC30456.1 - 0.087 12.6 0.1 0.096 12.4 0.1 1.1 1 0 0 1 1 1 0 Lysine methyltransferase Coiled PF05710.12 EGC30457.1 - 1.6e-18 67.3 16.6 1.8e-18 67.1 16.6 1.0 1 0 0 1 1 1 1 Coiled coil Endosulfine PF04667.17 EGC30458.1 - 1.6e-13 50.6 1.8 1.7e-13 50.5 1.8 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pkinase PF00069.25 EGC30459.1 - 6.5e-67 225.7 0.0 8.9e-67 225.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30459.1 - 1.1e-52 179.0 0.0 1.5e-52 178.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC30459.1 - 1.3e-07 30.8 0.0 2.4e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC30459.1 - 1.4e-06 27.8 0.0 8.8e-06 25.2 0.0 2.1 2 1 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGC30459.1 - 0.029 13.7 0.1 0.046 13.1 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC30459.1 - 0.052 13.5 0.0 0.093 12.6 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family FTA2 PF13095.6 EGC30459.1 - 0.093 12.3 0.2 6.2 6.4 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 YrbL-PhoP_reg PF10707.9 EGC30459.1 - 0.17 11.4 0.7 1.1 8.7 0.1 2.1 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Tyr-DNA_phospho PF06087.12 EGC30460.1 - 8e-60 202.9 3.7 1.1e-59 202.5 3.7 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.6 EGC30460.1 - 0.0097 15.8 0.2 0.2 11.5 0.1 2.4 2 0 0 2 2 2 1 PLD-like domain DUF3439 PF11921.8 EGC30460.1 - 0.15 12.1 6.7 0.34 10.9 6.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EGC30460.1 - 0.48 8.4 16.6 1.4 6.8 13.8 2.1 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein FSA_C PF10479.9 EGC30460.1 - 1.4 7.0 11.4 2.1 6.4 11.4 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGC30460.1 - 2.5 8.1 21.4 4.4 7.3 21.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein rhaM PF05336.13 EGC30461.1 - 7.5e-28 96.7 1.2 8.7e-28 96.5 1.2 1.0 1 0 0 1 1 1 1 L-rhamnose mutarotase TraB PF01963.17 EGC30462.1 - 2.1e-22 80.3 0.1 5.3e-15 56.0 0.0 2.9 2 2 1 3 3 3 2 TraB family Coiled PF05710.12 EGC30464.1 - 1.5e-08 35.3 16.5 1.7e-08 35.1 16.5 1.0 1 0 0 1 1 1 1 Coiled coil NIF PF03031.18 EGC30465.1 - 1.8e-22 79.8 1.6 1.8e-22 79.8 1.6 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase ubiquitin PF00240.23 EGC30465.1 - 5.6e-08 32.4 0.4 2.2e-07 30.5 0.4 2.1 1 0 0 1 1 1 1 Ubiquitin family Peptidase_S7 PF00949.21 EGC30465.1 - 0.012 15.5 0.2 0.031 14.1 0.2 1.8 1 0 0 1 1 1 0 Peptidase S7, Flavivirus NS3 serine protease Rad60-SLD PF11976.8 EGC30465.1 - 0.027 14.3 0.2 0.081 12.8 0.2 1.8 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like DUF3439 PF11921.8 EGC30466.1 - 0.093 12.7 9.5 0.22 11.5 9.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF971 PF06155.12 EGC30467.1 - 1e-24 87.0 0.0 1.9e-24 86.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) UCH PF00443.29 EGC30468.1 - 0.0013 18.3 0.0 0.0024 17.4 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LIM PF00412.22 EGC30469.1 - 3.4e-22 78.4 32.3 5.2e-08 33.0 3.5 3.3 3 0 0 3 3 3 3 LIM domain VCX_VCY PF15231.6 EGC30469.1 - 0.00046 20.9 11.5 0.00046 20.9 11.5 2.8 2 1 1 3 3 3 2 Variable charge X/Y family C1_1 PF00130.22 EGC30469.1 - 0.00076 19.3 21.9 0.12 12.3 1.8 3.6 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF3716 PF12511.8 EGC30469.1 - 0.002 18.2 17.2 0.98 9.5 2.5 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3716) PHF5 PF03660.14 EGC30469.1 - 1.3 9.2 20.1 0.43 10.8 1.8 3.3 3 0 0 3 3 3 0 PHF5-like protein XAF1_C PF18608.1 EGC30469.1 - 1.8 8.2 9.4 0.79 9.3 0.5 3.6 3 0 0 3 3 3 0 XIAP-associated factor 1 C-terminal domain SIR2 PF02146.17 EGC30469.1 - 2.7 7.9 10.9 0.27 11.1 0.3 3.1 3 0 0 3 3 3 0 Sir2 family MTHFR_C PF12225.8 EGC30469.1 - 5.2 6.8 24.0 2.1 8.0 1.1 4.5 3 3 2 5 5 5 0 Methylene-tetrahydrofolate reductase C terminal Methyltr_RsmB-F PF01189.17 EGC30470.1 - 1.9e-40 138.6 0.0 3.7e-40 137.7 0.0 1.5 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGC30470.1 - 9.3e-06 25.9 0.0 1.8e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase PUA PF01472.20 EGC30470.1 - 2.3e-05 24.3 0.3 6.1e-05 22.9 0.3 1.8 1 1 0 1 1 1 1 PUA domain PcfK PF14058.6 EGC30470.1 - 0.037 14.3 1.4 0.068 13.5 1.4 1.4 1 0 0 1 1 1 0 PcfK-like protein Methyltransf_24 PF13578.6 EGC30470.1 - 0.11 13.5 0.0 0.27 12.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain FF PF01846.19 EGC30470.1 - 0.19 11.9 1.5 0.33 11.2 0.3 2.0 2 0 0 2 2 2 0 FF domain PET122 PF05476.11 EGC30470.1 - 0.24 10.7 6.4 0.41 9.9 6.4 1.3 1 0 0 1 1 1 0 PET122 CemA PF03040.14 EGC30470.1 - 2.1 8.2 7.9 0.39 10.6 3.4 2.1 2 1 1 3 3 3 0 CemA family FNIP PF05725.12 EGC30471.1 - 6.4e-17 61.4 58.6 1.5e-08 34.7 3.2 11.7 7 2 5 12 12 12 9 FNIP Repeat DNase_II PF03265.15 EGC30473.1 - 7.9e-95 317.8 8.5 8.9e-95 317.7 8.5 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II TPP_enzyme_N PF02776.18 EGC30474.1 - 4.2e-20 72.0 0.0 2.8e-18 66.1 0.0 2.4 2 1 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGC30474.1 - 2.5e-09 37.1 0.4 6.6e-08 32.5 0.0 3.4 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGC30474.1 - 0.0016 18.2 0.0 0.0077 16.0 0.0 2.0 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF3875 PF12991.7 EGC30474.1 - 0.0024 17.8 0.1 0.39 10.7 0.1 2.8 2 0 0 2 2 2 1 Domain of unknown function, B. Theta Gene description (DUF3875) CO_dh PF02552.16 EGC30474.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit WD40_like PF17005.5 EGC30475.1 - 7.2e-06 25.5 1.8 0.18 11.1 0.0 3.2 2 1 1 3 3 3 3 WD40-like domain BBS2_Mid PF14783.6 EGC30475.1 - 0.00025 21.0 0.9 0.0008 19.4 0.0 2.3 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CDC45 PF02724.14 EGC30475.1 - 0.032 12.5 13.8 0.045 12.0 13.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGC30475.1 - 1.5 8.2 25.9 2.4 7.5 25.9 1.2 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGC30475.1 - 8.2 4.5 29.3 12 3.9 29.3 1.2 1 0 0 1 1 1 0 Nop14-like family I_LWEQ PF01608.17 EGC30476.1 - 4.6e-54 182.8 158.1 2.3e-39 135.1 16.3 16.0 8 4 8 19 19 19 14 I/LWEQ domain FERM_M PF00373.18 EGC30476.1 - 6.1e-26 91.1 0.3 5.5e-25 88.1 0.1 2.9 2 0 0 2 2 2 1 FERM central domain FERM_f0 PF16511.5 EGC30476.1 - 2.2e-25 88.8 0.1 8.4e-22 77.3 0.0 2.9 2 0 0 2 2 2 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 EGC30476.1 - 7.6e-11 41.8 0.3 2e-09 37.3 0.0 3.2 3 0 0 3 3 3 1 FERM N-terminal domain VBS PF08913.10 EGC30476.1 - 2.2e-05 24.9 1.7 2.2e-05 24.9 1.7 12.5 14 3 1 16 16 16 3 Vinculin Binding Site ACBP PF00887.19 EGC30476.1 - 0.00024 21.3 0.5 0.0014 18.8 0.1 2.6 2 0 0 2 2 2 1 Acyl CoA binding protein PID PF00640.23 EGC30476.1 - 0.00042 20.4 1.9 0.011 15.7 0.0 3.6 3 0 0 3 3 3 1 Phosphotyrosine interaction domain (PTB/PID) Rad60-SLD PF11976.8 EGC30476.1 - 0.0043 16.8 0.1 0.02 14.7 0.1 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Xpo1 PF08389.12 EGC30476.1 - 0.068 13.2 7.5 2.4 8.2 0.1 4.4 3 0 0 3 3 3 0 Exportin 1-like protein IRS PF02174.17 EGC30476.1 - 0.13 12.2 0.0 0.37 10.7 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) IPK PF03770.16 EGC30478.1 - 5.6e-54 183.0 0.1 1.3e-53 181.9 0.1 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase Mucin PF01456.17 EGC30478.1 - 0.97 9.4 15.8 0.15 12.0 2.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Autophagy_act_C PF03987.15 EGC30479.1 - 4.8e-17 62.3 2.3 9.5e-17 61.3 2.3 1.5 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Rab_bind PF16704.5 EGC30479.1 - 0.026 14.5 0.1 0.069 13.2 0.1 1.7 1 0 0 1 1 1 0 Rab binding domain Phos_pyr_kin PF08543.12 EGC30480.1 - 9.7e-16 57.9 0.0 1.5e-15 57.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.24 EGC30480.1 - 2.8e-10 40.0 0.2 6.6e-10 38.8 0.0 1.7 2 0 0 2 2 2 1 pfkB family carbohydrate kinase SARAF PF06682.12 EGC30481.1 - 0.00013 21.8 0.4 0.0043 16.8 0.1 2.4 2 0 0 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis MFS_Mycoplasma PF07672.13 EGC30481.1 - 0.017 14.4 0.2 0.017 14.4 0.2 1.9 2 0 0 2 2 2 0 Mycoplasma MFS transporter 7tm_1 PF00001.21 EGC30481.1 - 0.019 14.3 0.1 0.023 14.1 0.1 1.0 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF4064 PF13273.6 EGC30481.1 - 0.13 12.6 4.6 0.65 10.3 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Wzy_C PF04932.15 EGC30481.1 - 0.16 11.6 3.1 2 8.0 1.5 2.1 2 0 0 2 2 2 0 O-Antigen ligase DUF3333 PF11812.8 EGC30481.1 - 2.2 8.4 5.0 33 4.7 0.0 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3333) DUF229 PF02995.17 EGC30482.1 - 2.7e-39 135.1 0.5 6.1e-39 134.0 0.5 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 EGC30482.1 - 0.0022 17.5 0.1 0.0034 16.8 0.1 1.4 1 0 0 1 1 1 1 Sulfatase DUF3760 PF12586.8 EGC30482.1 - 0.027 14.6 0.0 0.065 13.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3760) Molybdopterin_N PF18364.1 EGC30482.1 - 0.15 12.1 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin oxidoreductase N-terminal domain 7TM_GPCR_Srw PF10324.9 EGC30483.1 - 0.26 10.6 4.4 0.26 10.5 0.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Androgen_recep PF02166.16 EGC30483.1 - 0.5 9.2 13.1 1.6 7.5 0.9 2.1 2 0 0 2 2 2 0 Androgen receptor CSG2 PF16965.5 EGC30483.1 - 8.6 5.2 9.5 0.62 8.9 1.2 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator UPRTase PF14681.6 EGC30484.1 - 5.9e-66 221.9 0.0 8.2e-66 221.4 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.18 EGC30484.1 - 3.8e-55 186.7 0.1 5.6e-55 186.1 0.1 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGC30484.1 - 1e-06 29.3 0.0 2.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGC30484.1 - 6e-05 23.5 0.4 0.51 10.8 0.0 2.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.6 EGC30484.1 - 0.001 19.2 0.0 0.0027 17.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain CoaE PF01121.20 EGC30484.1 - 0.0023 17.6 0.3 0.43 10.2 0.3 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase Pribosyltran PF00156.27 EGC30484.1 - 0.0078 15.7 0.0 0.028 13.9 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain Cytidylate_kin PF02224.18 EGC30484.1 - 0.015 15.1 0.1 4.9 6.8 0.0 2.2 2 0 0 2 2 2 0 Cytidylate kinase Zeta_toxin PF06414.12 EGC30484.1 - 0.067 12.5 0.0 0.15 11.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin MobB PF03205.14 EGC30484.1 - 0.15 11.9 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Spermine_synth PF01564.17 EGC30485.1 - 3.4e-66 222.3 0.0 5.8e-66 221.5 0.0 1.4 1 0 0 1 1 1 1 Spermine/spermidine synthase domain Spermine_synt_N PF17284.2 EGC30485.1 - 1.1e-23 82.9 0.1 1.8e-23 82.1 0.1 1.4 1 0 0 1 1 1 1 Spermidine synthase tetramerisation domain Methyltransf_25 PF13649.6 EGC30485.1 - 0.00087 20.0 0.0 0.0019 18.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC30485.1 - 0.14 12.1 0.0 0.32 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGC30485.1 - 0.18 12.6 0.0 0.55 11.0 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain OST-HTH PF12872.7 EGC30486.1 - 0.11 12.4 0.7 0.15 11.9 0.6 1.4 1 1 0 1 1 1 0 OST-HTH/LOTUS domain PDDEXK_1 PF12705.7 EGC30487.1 - 7.2e-09 35.9 4.7 4.6e-06 26.7 0.5 2.7 2 1 0 2 2 2 2 PD-(D/E)XK nuclease superfamily BBS2_Mid PF14783.6 EGC30487.1 - 0.00049 20.1 1.3 0.0079 16.2 0.0 3.0 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region RsmJ PF04378.13 EGC30487.1 - 0.076 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA large subunit methyltransferase D, RlmJ Cas_Cas4 PF01930.17 EGC30487.1 - 0.086 12.9 0.1 0.086 12.9 0.1 4.0 3 1 2 5 5 5 0 Domain of unknown function DUF83 GNVR PF13807.6 EGC30487.1 - 0.19 11.6 8.1 3.9 7.5 0.2 3.7 2 1 2 4 4 4 0 G-rich domain on putative tyrosine kinase AntA PF08346.12 EGC30487.1 - 0.26 11.9 3.2 17 6.0 0.1 3.7 3 0 0 3 3 3 0 AntA/AntB antirepressor TIG PF01833.24 EGC30488.1 - 1.3e-13 50.8 39.7 1.8e-05 24.7 5.1 6.1 4 2 2 6 6 6 4 IPT/TIG domain EGF_2 PF07974.13 EGC30488.1 - 1.4e-05 25.3 12.3 2.8e-05 24.4 12.3 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGC30488.1 - 0.034 14.3 7.4 0.079 13.1 7.4 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC30488.1 - 0.13 12.3 1.9 1.6 8.9 2.6 2.3 2 0 0 2 2 2 0 Tenascin EGF domain EGF PF00008.27 EGC30488.1 - 0.72 10.2 7.9 1.8 8.9 7.9 1.7 1 0 0 1 1 1 0 EGF-like domain hEGF PF12661.7 EGC30488.1 - 1.1 10.0 7.7 3 8.6 7.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF ANAPC4_WD40 PF12894.7 EGC30489.1 - 4e-07 30.2 0.0 0.53 10.6 0.0 4.5 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC30489.1 - 5.4e-06 27.0 4.3 1.1 10.2 0.0 6.1 6 1 0 6 6 6 2 WD domain, G-beta repeat LRR_9 PF14580.6 EGC30489.1 - 0.00058 19.4 1.2 0.00089 18.8 0.2 1.8 2 0 0 2 2 2 1 Leucine-rich repeat FAM176 PF14851.6 EGC30490.1 - 0.081 12.6 0.1 0.081 12.6 0.1 3.2 2 1 0 2 2 2 0 FAM176 family DUF4834 PF16118.5 EGC30490.1 - 0.28 12.2 0.2 0.28 12.2 0.2 3.7 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) Methyltransf_11 PF08241.12 EGC30491.1 - 1.1e-16 61.2 0.0 1.7e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30491.1 - 6.4e-13 49.2 0.0 1.1e-12 48.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC30491.1 - 1.4e-08 34.7 0.0 1.8e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC30491.1 - 2.8e-08 34.4 0.0 5e-08 33.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC30491.1 - 3.3e-08 33.5 0.0 4.4e-08 33.1 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC30491.1 - 0.00023 20.6 0.0 0.00065 19.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGC30491.1 - 0.001 18.5 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_8 PF05148.15 EGC30491.1 - 0.0063 16.4 0.0 0.012 15.4 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase ANT PF03374.14 EGC30491.1 - 0.007 16.7 0.1 0.018 15.3 0.1 1.7 1 1 0 1 1 1 1 Phage antirepressor protein KilAC domain Methyltransf_4 PF02390.17 EGC30491.1 - 0.05 13.1 0.0 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase DREV PF05219.12 EGC30491.1 - 0.056 12.5 0.0 0.07 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase tRNA_U5-meth_tr PF05958.11 EGC30491.1 - 0.073 12.1 0.0 0.1 11.5 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Methyltransf_15 PF09445.10 EGC30491.1 - 0.073 12.6 0.0 0.17 11.4 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_9 PF08003.11 EGC30491.1 - 0.073 12.0 0.0 0.12 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) RrnaAD PF00398.20 EGC30491.1 - 0.085 11.9 0.0 0.14 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_32 PF13679.6 EGC30491.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain An_peroxidase PF03098.15 EGC30492.1 - 5e-135 451.1 0.1 5.6e-135 450.9 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Orai-1 PF07856.12 EGC30493.1 - 0.025 14.3 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF3923 PF13061.6 EGC30493.1 - 0.37 10.9 4.7 1 9.5 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Myc_N PF01056.18 EGC30494.1 - 0.049 13.5 4.3 0.054 13.4 4.3 1.1 1 0 0 1 1 1 0 Myc amino-terminal region DUF3807 PF12720.7 EGC30494.1 - 0.21 11.9 10.6 0.23 11.7 10.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) POX PF07526.11 EGC30494.1 - 0.47 11.0 4.5 0.55 10.8 4.5 1.1 1 0 0 1 1 1 0 Associated with HOX Gti1_Pac2 PF09729.9 EGC30494.1 - 0.62 10.1 11.0 0.72 9.9 11.0 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family AAR2 PF05282.11 EGC30494.1 - 1.5 8.2 8.4 1.7 8.0 8.4 1.1 1 0 0 1 1 1 0 AAR2 protein Presenilin PF01080.17 EGC30494.1 - 1.7 7.3 9.0 1.8 7.3 9.0 1.0 1 0 0 1 1 1 0 Presenilin FAM60A PF15396.6 EGC30494.1 - 1.8 8.5 10.0 2.2 8.2 10.0 1.0 1 0 0 1 1 1 0 Protein Family FAM60A Menin PF05053.13 EGC30494.1 - 2.3 6.5 13.9 2.4 6.4 13.9 1.1 1 0 0 1 1 1 0 Menin CPSF100_C PF13299.6 EGC30494.1 - 2.5 8.3 7.0 3 8.0 7.0 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Zip PF02535.22 EGC30494.1 - 4.6 6.4 5.7 4.8 6.3 5.7 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter GCD14 PF08704.10 EGC30494.1 - 4.7 6.8 7.5 5 6.7 7.5 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit ALMT PF11744.8 EGC30494.1 - 5.9 5.6 10.4 6.7 5.4 10.4 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4637 PF15470.6 EGC30494.1 - 6.7 6.4 6.0 7.9 6.2 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) CSG2 PF16965.5 EGC30494.1 - 8.8 5.2 9.1 9.6 5.0 9.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator DUF3537 PF12056.8 EGC30494.1 - 9.7 4.9 4.8 11 4.7 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) DUF4969 PF16339.5 EGC30495.1 - 0.24 11.8 0.1 0.24 11.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) PGG PF13962.6 EGC30495.1 - 0.27 11.1 3.0 0.41 10.5 3.0 1.2 1 0 0 1 1 1 0 Domain of unknown function Cyt-b5 PF00173.28 EGC30497.1 - 2e-20 72.7 0.1 2.7e-20 72.3 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-C3HC4_3 PF13920.6 EGC30498.1 - 1.1e-07 31.6 9.9 2e-07 30.8 9.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC30498.1 - 2.5e-07 30.9 13.6 2.5e-07 30.9 13.6 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC30498.1 - 7.9e-06 25.6 11.9 1.5e-05 24.8 11.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30498.1 - 4.4e-05 23.2 14.1 9.2e-05 22.2 14.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC30498.1 - 0.00019 21.6 8.3 0.00019 21.6 8.3 2.7 3 0 0 3 3 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC30498.1 - 0.0018 18.2 5.2 0.0028 17.7 4.2 1.9 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGC30498.1 - 0.0029 17.3 7.7 0.0068 16.1 7.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC30498.1 - 0.013 15.3 12.0 0.023 14.5 12.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SPX PF03105.19 EGC30498.1 - 0.045 13.7 16.7 0.067 13.1 16.7 1.2 1 0 0 1 1 1 0 SPX domain Exonuc_VII_L PF02601.15 EGC30498.1 - 0.07 12.7 1.9 0.092 12.3 1.9 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_5 PF14634.6 EGC30498.1 - 0.089 12.8 16.5 0.053 13.5 12.8 2.5 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC30498.1 - 0.091 12.9 10.6 0.77 10.0 10.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Atrophin-1 PF03154.15 EGC30498.1 - 0.18 10.0 25.2 0.23 9.7 25.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family AAA_23 PF13476.6 EGC30498.1 - 1.4 9.4 12.6 2.1 8.8 12.6 1.2 1 0 0 1 1 1 0 AAA domain zf-ANAPC11 PF12861.7 EGC30498.1 - 1.6 8.8 8.3 0.051 13.6 1.4 2.1 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GBP_C PF02841.14 EGC30498.1 - 3.6 6.9 18.9 5.2 6.4 18.9 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain GvpL_GvpF PF06386.11 EGC30498.1 - 9.6 6.0 11.2 19 5.1 11.2 1.4 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF OTU PF02338.19 EGC30499.1 - 4.5e-12 46.6 0.1 9.5e-12 45.5 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease SAP PF02037.27 EGC30501.1 - 6.8e-05 22.5 0.0 0.00017 21.2 0.0 1.7 1 0 0 1 1 1 1 SAP domain Transferase PF02458.15 EGC30502.1 - 5.6e-13 48.3 0.1 9e-13 47.7 0.1 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 EGC30502.1 - 0.0059 15.3 0.0 0.012 14.3 0.0 1.4 2 0 0 2 2 2 1 Condensation domain Annexin PF00191.20 EGC30503.1 - 3.4e-84 276.9 8.6 1.1e-23 83.0 0.1 4.1 4 0 0 4 4 4 4 Annexin DUF3574 PF12098.8 EGC30503.1 - 0.091 12.6 0.0 0.57 10.0 0.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3574) zf-RING_2 PF13639.6 EGC30504.1 - 3.9e-11 43.1 5.9 1e-10 41.8 5.9 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC30504.1 - 1.6e-08 34.4 4.5 5.1e-08 32.8 4.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC30504.1 - 1e-07 31.7 6.3 2.3e-07 30.5 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC30504.1 - 1.5e-07 31.1 4.4 3.2e-07 30.1 4.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30504.1 - 1.5e-06 28.0 6.9 4.9e-06 26.3 6.9 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC30504.1 - 2.7e-06 27.4 5.6 7.9e-06 25.9 5.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC30504.1 - 2.9e-06 27.1 6.3 6.5e-06 26.0 6.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.8 EGC30504.1 - 6.5e-06 25.9 3.3 2.3e-05 24.1 2.0 2.6 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EGC30504.1 - 2.1e-05 24.7 10.0 2.3e-05 24.6 5.6 3.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC30504.1 - 6.9e-05 22.6 7.5 0.0016 18.3 8.2 2.5 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC30504.1 - 0.29 11.2 3.2 0.26 11.4 1.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC30504.1 - 0.61 9.9 2.2 1.8 8.4 2.2 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGC30504.1 - 1.4 8.8 9.7 0.13 12.0 3.7 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF3439 PF11921.8 EGC30504.1 - 3.4 7.7 24.1 3 7.8 0.3 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Profilin PF00235.19 EGC30505.1 - 6.4e-06 26.5 0.0 6.9e-06 26.4 0.0 1.0 1 0 0 1 1 1 1 Profilin SLH PF00395.20 EGC30505.1 - 0.053 13.5 0.0 0.11 12.6 0.0 1.5 1 0 0 1 1 1 0 S-layer homology domain MOSC_N PF03476.16 EGC30506.1 - 6.4e-24 84.1 0.0 1.6e-23 82.9 0.0 1.7 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EGC30506.1 - 1.9e-23 82.9 0.0 2.6e-22 79.2 0.0 2.6 3 1 0 3 3 3 1 MOSC domain p450 PF00067.22 EGC30507.1 - 2.8e-84 283.5 0.0 3.1e-84 283.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CD36 PF01130.21 EGC30508.1 - 1.1e-49 169.2 0.5 1.5e-27 96.3 0.0 2.1 2 0 0 2 2 2 2 CD36 family ProRS-C_2 PF09181.10 EGC30509.1 - 0.068 13.3 2.5 0.23 11.6 2.5 1.9 1 1 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal FAM163 PF15069.6 EGC30510.1 - 0.0062 17.0 3.3 0.0081 16.6 1.0 2.1 1 1 1 2 2 2 1 FAM163 family DUF4834 PF16118.5 EGC30510.1 - 0.11 13.4 1.4 0.43 11.6 1.4 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Cadherin_C_2 PF16492.5 EGC30510.1 - 5 7.9 8.6 19 6.1 8.6 2.2 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal ANAPC5 PF12862.7 EGC30511.1 - 3.1e-35 120.1 3.8 3.9e-34 116.6 1.2 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_8 PF13181.6 EGC30511.1 - 4.1e-05 23.4 14.0 0.012 15.8 0.3 5.6 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC30511.1 - 4.9e-05 23.5 4.4 2 8.7 0.7 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC30511.1 - 0.0035 17.1 2.2 0.29 11.1 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC30511.1 - 0.032 14.1 0.2 88 3.2 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC30511.1 - 0.062 13.7 7.0 2.9 8.5 0.0 3.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC30511.1 - 0.22 11.7 5.8 36 4.8 0.2 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Pkinase PF00069.25 EGC30512.1 - 5.8e-52 176.7 0.4 9.3e-52 176.0 0.4 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30512.1 - 1.3e-30 106.6 0.1 1.9e-30 106.0 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.16 EGC30512.1 - 1.3e-11 44.0 0.3 8.2e-10 38.1 0.1 2.3 2 0 0 2 2 2 1 ANTH domain Kinase-like PF14531.6 EGC30512.1 - 0.00074 18.9 0.0 0.37 10.0 0.0 2.5 2 0 0 2 2 2 2 Kinase-like APH PF01636.23 EGC30512.1 - 0.0011 18.9 0.0 1.8 8.4 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family HEPN PF05168.14 EGC30512.1 - 0.22 11.6 0.2 0.48 10.6 0.2 1.5 1 0 0 1 1 1 0 HEPN domain Ank_2 PF12796.7 EGC30513.1 - 7.7e-24 84.1 0.1 1e-11 45.3 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC30513.1 - 1.5e-23 80.3 2.5 1.6e-05 24.9 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.6 EGC30513.1 - 5.1e-23 81.1 5.1 1.3e-07 32.0 0.1 3.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC30513.1 - 1e-20 73.5 6.6 3.1e-08 33.7 0.2 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC30513.1 - 3.9e-19 68.2 1.8 7.8e-06 26.1 0.4 4.1 4 0 0 4 4 4 4 Ankyrin repeat BTB PF00651.31 EGC30514.1 - 2.3e-16 60.0 0.3 6.2e-15 55.4 0.0 2.8 2 1 1 3 3 3 1 BTB/POZ domain TFIIB PF00382.19 EGC30515.1 - 0.013 15.5 0.1 0.082 13.0 0.0 2.3 3 0 0 3 3 3 0 Transcription factor TFIIB repeat TrpP PF17099.5 EGC30515.1 - 0.016 14.9 0.5 0.03 14.1 0.5 1.3 1 0 0 1 1 1 0 Tryptophan transporter TrpP Synaptobrevin PF00957.21 EGC30516.1 - 1.5e-29 101.6 7.5 1.7e-29 101.5 7.5 1.0 1 0 0 1 1 1 1 Synaptobrevin UPF0258 PF06789.12 EGC30516.1 - 0.0038 17.4 6.0 0.004 17.3 5.8 1.2 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0258) LMBR1 PF04791.16 EGC30516.1 - 0.0064 15.4 0.8 0.0066 15.4 0.8 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF4199 PF13858.6 EGC30516.1 - 0.0075 16.7 0.2 0.0092 16.4 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF4199) Orf78 PF06024.12 EGC30516.1 - 0.024 14.9 1.4 0.03 14.6 1.4 1.2 1 0 0 1 1 1 0 Orf78 (ac78) TACC_C PF05010.14 EGC30516.1 - 0.03 14.1 2.9 0.034 13.9 2.9 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LRRC37AB_C PF14914.6 EGC30516.1 - 0.04 13.8 1.9 0.049 13.6 1.9 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain DUF2207 PF09972.9 EGC30516.1 - 0.054 12.2 0.1 0.053 12.3 0.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CD34_antigen PF06365.12 EGC30516.1 - 0.057 13.0 3.2 0.066 12.8 3.2 1.0 1 0 0 1 1 1 0 CD34/Podocalyxin family Fzo_mitofusin PF04799.13 EGC30516.1 - 0.06 12.9 2.9 0.089 12.3 2.9 1.3 1 0 0 1 1 1 0 fzo-like conserved region DUF2570 PF10828.8 EGC30516.1 - 0.13 12.1 4.8 0.16 11.8 4.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) NPV_P10 PF05531.12 EGC30516.1 - 0.37 11.3 5.6 2.9 8.4 5.6 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein Med11 PF10280.9 EGC30517.1 - 5.3e-06 26.9 3.7 9.1e-06 26.2 2.8 1.7 1 1 1 2 2 2 1 Mediator complex protein DUF5595 PF18077.1 EGC30517.1 - 0.068 13.2 3.1 0.17 12.0 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5595) F-box-like PF12937.7 EGC30518.1 - 4.6e-11 42.4 0.5 8e-11 41.7 0.5 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC30518.1 - 1.5e-05 24.7 0.6 3.1e-05 23.7 0.6 1.5 1 0 0 1 1 1 1 F-box domain Glyco_hydro_42M PF08532.10 EGC30518.1 - 0.14 11.6 0.7 2.1 7.8 0.0 2.2 2 0 0 2 2 2 0 Beta-galactosidase trimerisation domain DUF1412 PF07203.11 EGC30518.1 - 0.43 10.8 4.8 0.52 10.5 1.7 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) Synapsin_C PF02750.14 EGC30520.1 - 0.062 12.8 0.0 0.088 12.3 0.0 1.3 1 0 0 1 1 1 0 Synapsin, ATP binding domain MORN PF02493.20 EGC30523.1 - 0.028 14.3 0.2 0.028 14.3 0.2 2.8 3 0 0 3 3 3 0 MORN repeat MMR_HSR1 PF01926.23 EGC30524.1 - 2.7e-06 27.4 0.3 1.6e-05 24.9 0.0 2.5 1 1 1 3 3 3 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGC30524.1 - 0.00021 21.8 1.6 0.00056 20.4 0.0 2.4 2 1 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EGC30524.1 - 0.00054 19.9 0.3 0.0028 17.6 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase AAA_23 PF13476.6 EGC30524.1 - 0.0015 19.1 20.7 0.16 12.5 20.7 2.8 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EGC30524.1 - 0.0059 16.2 0.7 0.013 15.0 0.0 1.8 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EGC30524.1 - 0.0062 15.7 2.9 0.028 13.6 0.0 2.7 3 0 0 3 3 3 1 NB-ARC domain TsaE PF02367.17 EGC30524.1 - 0.0068 16.4 0.0 0.018 15.0 0.0 1.7 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Dynamin_N PF00350.23 EGC30524.1 - 0.014 15.5 3.1 0.47 10.5 0.0 3.2 2 2 1 3 3 3 0 Dynamin family MobB PF03205.14 EGC30524.1 - 0.022 14.7 0.0 0.064 13.1 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 EGC30524.1 - 0.03 13.4 0.0 0.062 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGC30524.1 - 0.034 14.3 0.0 0.14 12.3 0.0 2.0 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EGC30524.1 - 0.055 13.6 0.3 0.23 11.6 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA_29 PF13555.6 EGC30524.1 - 0.069 12.9 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA PF00004.29 EGC30524.1 - 0.075 13.5 0.3 0.4 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGC30524.1 - 0.096 12.2 0.6 0.45 10.0 0.1 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGC30524.1 - 0.14 12.5 0.0 0.54 10.6 0.0 2.0 2 1 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGC30524.1 - 0.15 12.4 0.2 1.6 9.0 0.0 2.6 3 0 0 3 3 3 0 AAA domain tRNA-synt_His PF13393.6 EGC30524.1 - 0.56 9.4 2.0 0.93 8.7 2.0 1.2 1 0 0 1 1 1 0 Histidyl-tRNA synthetase DUF87 PF01935.17 EGC30524.1 - 3.5 7.6 9.8 2.7 8.0 0.2 3.1 2 1 1 3 3 3 0 Helicase HerA, central domain FUSC PF04632.12 EGC30525.1 - 1.2 7.6 10.1 1.2 7.6 10.1 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family Peptidase_C3 PF00548.20 EGC30525.1 - 6.6 6.6 7.3 2.1 8.3 4.6 1.5 1 1 1 2 2 2 0 3C cysteine protease (picornain 3C) HSP70 PF00012.20 EGC30525.1 - 7.9 4.5 19.8 7.8 4.5 19.8 1.1 1 0 0 1 1 1 0 Hsp70 protein DAOA PF15199.6 EGC30527.1 - 0.043 14.2 0.4 0.052 14.0 0.4 1.1 1 0 0 1 1 1 0 D-amino acid oxidase activator DUF3757 PF12582.8 EGC30527.1 - 0.05 14.0 1.3 0.056 13.9 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3757) Lipoprotein_3 PF00938.17 EGC30528.1 - 3.3 8.0 6.5 0.77 10.0 0.9 2.5 2 1 1 3 3 3 0 Lipoprotein FNIP PF05725.12 EGC30529.1 - 7.6e-17 61.2 21.0 5.3e-09 36.1 2.7 5.8 4 2 0 4 4 4 3 FNIP Repeat GATA PF00320.27 EGC30530.1 - 0.026 14.1 0.8 0.026 14.1 0.8 1.9 2 0 0 2 2 2 0 GATA zinc finger DUF1489 PF07370.11 EGC30530.1 - 0.14 11.9 0.0 0.21 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) DZR PF12773.7 EGC30530.1 - 0.27 11.3 3.3 1.3 9.1 3.3 1.9 1 1 0 1 1 1 0 Double zinc ribbon Cwf_Cwc_15 PF04889.12 EGC30530.1 - 0.29 10.8 11.5 0.41 10.3 11.5 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RNA_pol_3_Rpc31 PF11705.8 EGC30530.1 - 0.51 10.6 15.2 0.69 10.1 15.2 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 HBM PF16591.5 EGC30531.1 - 0.65 9.4 27.6 0.64 9.4 24.2 2.6 2 0 0 2 2 2 0 Helical bimodular sensor domain Plk4_PB2 PF18409.1 EGC30531.1 - 2.8 8.7 18.6 1.3 9.7 6.1 3.7 1 1 1 2 2 2 0 Polo-like Kinase 4 Polo Box 2 GATA PF00320.27 EGC30532.1 - 2.7e-07 30.0 8.8 1.3e-06 27.9 8.8 2.0 1 1 0 1 1 1 1 GATA zinc finger AT_hook PF02178.19 EGC30532.1 - 0.055 13.3 7.5 0.11 12.4 7.5 1.5 1 0 0 1 1 1 0 AT hook motif DUF4508 PF14969.6 EGC30532.1 - 0.06 13.6 0.2 0.085 13.1 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) RFX5_DNA_bdg PF14621.6 EGC30532.1 - 0.073 12.8 0.4 0.1 12.4 0.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain ELMO_CED12 PF04727.13 EGC30533.1 - 6.5e-39 133.9 0.1 6.5e-39 133.9 0.1 2.6 3 0 0 3 3 3 1 ELMO/CED-12 family Ank_2 PF12796.7 EGC30533.1 - 8.9e-21 74.3 1.2 5.8e-11 42.8 0.3 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC30533.1 - 8.3e-18 62.7 4.6 0.00015 22.0 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.6 EGC30533.1 - 1.6e-14 54.0 10.3 8.1e-09 35.9 0.4 5.3 4 2 2 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.30 EGC30533.1 - 1e-13 51.0 12.2 0.0024 18.2 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGC30533.1 - 5.7e-13 48.8 17.0 4e-08 33.4 0.2 5.5 3 2 2 5 5 5 4 Ankyrin repeats (many copies) DUF3361 PF11841.8 EGC30533.1 - 4.6e-05 23.4 0.5 0.00025 21.0 0.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF3361) DUF4042 PF13251.6 EGC30533.1 - 0.0027 17.4 0.0 0.0058 16.4 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) GRDP-like PF07173.12 EGC30533.1 - 0.33 11.6 0.0 0.33 11.6 0.0 4.4 3 2 1 5 5 5 0 Glycine-rich domain-containing protein-like Resolvase PF00239.21 EGC30535.1 - 4.1e-05 23.7 0.0 7.8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Resolvase, N terminal domain DUF4105 PF13387.6 EGC30535.1 - 0.0052 16.4 0.1 0.18 11.4 0.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4105) SPT16 PF08644.11 EGC30535.1 - 0.074 13.2 3.4 1.7 8.8 0.2 2.3 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) GGDEF_2 PF17853.1 EGC30535.1 - 0.19 12.0 0.0 0.32 11.3 0.0 1.3 1 0 0 1 1 1 0 GGDEF-like domain Mer2 PF09074.10 EGC30536.1 - 0.019 14.8 6.7 0.028 14.2 6.7 1.2 1 0 0 1 1 1 0 Mer2 Cas6b_C PF17262.2 EGC30536.1 - 0.16 12.1 2.6 0.26 11.4 1.6 2.0 1 1 1 2 2 2 0 Cas6b C-terminal domain Erg28 PF03694.13 EGC30537.1 - 2.1e-22 79.6 1.9 2.5e-22 79.3 1.9 1.1 1 0 0 1 1 1 1 Erg28 like protein MGAT2 PF05060.14 EGC30537.1 - 0.051 12.6 0.1 0.064 12.3 0.1 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) Inv-AAD PF18785.1 EGC30538.1 - 0.0037 17.1 0.0 0.01 15.7 0.0 1.6 2 0 0 2 2 2 1 Invertebrate-AID/APOBEC-deaminase DUF1133 PF06576.11 EGC30540.1 - 0.83 9.0 3.6 1 8.8 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) DUF3627 PF12299.8 EGC30541.1 - 1.6 8.8 13.4 2.2 8.4 7.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3627) HTH_23 PF13384.6 EGC30544.1 - 2.1e-11 43.3 0.1 7.1e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_38 PF13936.6 EGC30544.1 - 5.7e-07 29.2 2.7 3.5e-05 23.5 0.5 2.3 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.6 EGC30544.1 - 7.2e-07 29.7 0.1 1.3e-06 29.0 0.1 1.4 1 1 1 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.6 EGC30544.1 - 1.3e-06 28.4 0.2 4.3e-06 26.7 0.0 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_29 PF13551.6 EGC30544.1 - 2.2e-06 27.6 0.0 1.4e-05 25.0 0.0 2.0 2 0 0 2 2 2 1 Winged helix-turn helix HTH_7 PF02796.15 EGC30544.1 - 0.00015 21.7 1.0 0.036 14.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 EGC30544.1 - 0.0024 17.5 0.1 0.0044 16.7 0.1 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_33 PF13592.6 EGC30544.1 - 0.0026 17.4 0.0 0.0057 16.3 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_Tnp_1_2 PF13022.6 EGC30544.1 - 0.0033 17.6 0.1 0.0082 16.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix of insertion element transposase CENP-B_N PF04218.13 EGC30544.1 - 0.0034 17.0 0.5 0.029 14.0 0.1 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.20 EGC30544.1 - 0.04 14.2 0.0 0.062 13.6 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_3 PF01381.22 EGC30544.1 - 0.082 13.0 0.2 1.3 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_Tnp_4 PF13613.6 EGC30544.1 - 0.13 12.0 0.0 0.64 9.8 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Helicase_C PF00271.31 EGC30545.1 - 3.2e-14 53.2 0.0 5.3e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DDOST_48kD PF03345.14 EGC30545.1 - 0.011 14.6 0.1 0.014 14.3 0.1 1.0 1 0 0 1 1 1 0 Oligosaccharyltransferase 48 kDa subunit beta FNIP PF05725.12 EGC30547.1 - 2.7e-32 110.7 29.0 1.8e-07 31.2 0.1 6.3 3 3 5 8 8 8 8 FNIP Repeat Alpha_kinase PF02816.18 EGC30548.1 - 5e-51 173.4 0.2 5e-51 173.4 0.2 2.7 2 1 1 3 3 3 1 Alpha-kinase family PAF PF15715.5 EGC30548.1 - 0.076 13.6 9.9 0.15 12.7 9.9 1.4 1 0 0 1 1 1 0 PCNA-associated factor histone like domain C1_2 PF03107.16 EGC30548.1 - 4.2 7.8 16.1 0.66 10.3 12.0 1.9 2 0 0 2 2 2 0 C1 domain TIG PF01833.24 EGC30550.1 - 2.3e-12 46.8 30.1 1.9e-05 24.6 4.5 7.1 6 2 1 7 7 7 5 IPT/TIG domain Ank_2 PF12796.7 EGC30551.1 - 0.00053 20.5 0.1 0.0014 19.1 0.1 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC30551.1 - 0.0024 18.1 0.0 0.009 16.3 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC30551.1 - 0.07 13.7 0.0 0.18 12.4 0.0 1.8 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Mucin PF01456.17 EGC30551.1 - 2 8.4 18.5 0.58 10.1 11.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGC30551.1 - 5.5 7.0 13.6 0.22 11.5 4.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) B_lectin PF01453.24 EGC30552.1 - 0.0016 19.0 0.7 0.23 12.0 0.1 2.9 2 1 0 2 2 2 2 D-mannose binding lectin Pkinase_Tyr PF07714.17 EGC30555.1 - 6.8e-45 153.4 0.0 8.6e-45 153.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30555.1 - 2e-40 138.8 0.1 2.9e-40 138.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC30555.1 - 0.13 11.0 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase DpnI_C PF17726.1 EGC30555.1 - 0.22 11.6 0.0 0.22 11.6 0.0 2.5 2 1 0 2 2 2 0 Dam-replacing HTH domain TIG PF01833.24 EGC30556.1 - 1.9e-23 82.3 51.9 2.5e-07 30.6 0.3 7.8 7 1 0 7 7 7 6 IPT/TIG domain zf-H2C2 PF09337.10 EGC30558.1 - 0.043 14.1 0.5 0.076 13.2 0.5 1.4 1 0 0 1 1 1 0 H2C2 zinc finger GATA PF00320.27 EGC30558.1 - 0.24 11.0 3.5 0.68 9.6 3.5 1.8 1 1 0 1 1 1 0 GATA zinc finger RecR PF02132.15 EGC30558.1 - 1 9.0 5.9 2.4 7.8 5.9 1.7 1 1 0 1 1 1 0 RecR protein NST1 PF13945.6 EGC30559.1 - 0.73 9.9 15.9 1.1 9.3 15.9 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator ABC2_membrane_3 PF12698.7 EGC30559.1 - 4.5 6.3 16.5 6.5 5.8 16.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SAM_1 PF00536.30 EGC30560.1 - 2.8e-05 24.5 0.1 4.4e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC30560.1 - 0.00023 21.2 0.0 0.00036 20.6 0.0 1.3 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mucin PF01456.17 EGC30560.1 - 0.12 12.3 19.3 0.19 11.7 19.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Hamartin PF04388.12 EGC30560.1 - 0.28 9.8 20.9 0.34 9.5 20.9 1.0 1 0 0 1 1 1 0 Hamartin protein CAC1F_C PF16885.5 EGC30560.1 - 2.1 7.9 20.4 2.4 7.7 20.4 1.1 1 0 0 1 1 1 0 Voltage-gated calcium channel subunit alpha, C-term PRP38_assoc PF12871.7 EGC30560.1 - 7.7 7.2 10.5 56 4.4 9.4 2.1 2 0 0 2 2 2 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term Ndc1_Nup PF09531.10 EGC30560.1 - 8.6 4.9 11.3 9.4 4.8 11.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FSA_C PF10479.9 EGC30560.1 - 8.8 4.3 16.5 11 3.9 16.5 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus LBP_BPI_CETP PF01273.25 EGC30561.1 - 0.00023 20.8 0.4 0.00052 19.7 0.4 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Soyouz_module PF14313.6 EGC30561.1 - 0.00082 19.1 7.8 1.8 8.4 0.1 5.7 3 1 2 5 5 5 2 N-terminal region of Paramyxovirinae phosphoprotein (P) HEPN_AbiV PF18728.1 EGC30561.1 - 0.02 15.1 0.4 0.02 15.1 0.4 2.7 2 1 0 2 2 2 0 AbiV QIL1 PF15884.5 EGC30561.1 - 0.021 15.4 2.9 5.1 7.8 0.1 4.2 4 0 0 4 4 4 0 MICOS complex subunit MIC13, QIL1 Urease_gamma PF00547.18 EGC30561.1 - 0.052 13.9 2.2 1.2 9.5 0.1 3.6 4 1 1 5 5 5 0 Urease, gamma subunit DnaI_N PF07319.11 EGC30561.1 - 0.86 10.3 16.2 2.9 8.6 1.9 5.4 3 2 2 5 5 5 0 Primosomal protein DnaI N-terminus DUF4962 PF16332.5 EGC30561.1 - 4.1 5.8 10.6 0.27 9.7 4.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4962) NGP1NT PF08153.12 EGC30562.1 - 2.3e-44 150.7 1.3 7.4e-44 149.1 1.3 1.9 1 0 0 1 1 1 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.23 EGC30562.1 - 4.6e-17 62.2 0.2 1.1e-13 51.3 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC30562.1 - 2e-05 24.2 0.0 0.0014 18.2 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC30562.1 - 0.00015 21.7 0.0 0.0005 20.0 0.0 1.9 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGC30562.1 - 0.00073 19.0 0.2 0.44 10.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC30562.1 - 0.016 15.4 1.9 6.2 7.1 0.1 3.4 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGC30562.1 - 2.6 8.1 14.6 3.5 7.6 0.0 4.8 3 2 0 3 3 3 0 Dynamin family Ribosomal_L25p PF01386.19 EGC30563.1 - 1.3e-08 35.2 0.0 2.3e-08 34.4 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family eIF2_C PF09173.11 EGC30564.1 - 0.043 14.1 0.1 0.089 13.1 0.1 1.6 1 1 1 2 2 2 0 Initiation factor eIF2 gamma, C terminal DUF5522 PF17653.1 EGC30565.1 - 0.84 9.7 7.4 8.7 6.4 0.1 4.1 5 0 0 5 5 5 0 Family of unknown function (DUF5522) FAM163 PF15069.6 EGC30565.1 - 9.3 6.7 10.1 0.39 11.1 0.7 2.6 1 1 1 2 2 2 0 FAM163 family Beta-lactamase PF00144.24 EGC30566.1 - 1.8e-39 135.9 0.0 2.3e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Myosin_head PF00063.21 EGC30567.1 - 1.8e-282 938.6 13.7 2.6e-282 938.1 13.7 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC30567.1 - 1.1e-40 139.3 9.0 2.3e-40 138.3 9.0 1.6 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGC30567.1 - 2.5e-07 29.9 4.1 0.0013 18.3 1.2 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.12 EGC30567.1 - 0.0052 16.3 1.3 0.36 10.3 0.2 2.7 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_16 PF13191.6 EGC30567.1 - 0.048 14.1 0.0 0.11 12.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.6 EGC30567.1 - 0.096 13.2 0.0 0.34 11.4 0.0 2.0 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGC30567.1 - 0.1 12.5 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EGC30567.1 - 0.11 12.8 0.1 0.6 10.4 0.1 2.2 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC30567.1 - 0.12 12.8 0.4 1.3 9.4 0.0 2.7 2 0 0 2 2 2 0 RNA helicase Histone PF00125.24 EGC30568.1 - 0.00052 20.4 0.0 0.00084 19.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Histone_H2A_C PF16211.5 EGC30568.1 - 0.0038 16.9 0.4 0.0095 15.7 0.4 1.7 1 1 0 1 1 1 1 C-terminus of histone H2A polyprenyl_synt PF00348.17 EGC30569.1 - 3.3e-70 236.1 0.2 4.7e-70 235.6 0.2 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase RecG_N PF17190.4 EGC30569.1 - 0.0077 16.9 0.1 3.3 8.5 0.0 3.0 2 0 0 2 2 2 2 RecG N-terminal helical domain THF_DHG_CYH_C PF02882.19 EGC30570.1 - 8.7e-52 174.7 0.4 2.2e-50 170.1 0.1 2.2 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGC30570.1 - 2.6e-35 121.2 0.5 4.1e-35 120.5 0.5 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 EGC30570.1 - 0.055 12.8 0.0 0.1 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain TPR_8 PF13181.6 EGC30571.1 - 0.076 13.3 2.1 0.15 12.3 0.7 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.19 EGC30572.1 - 6e-25 88.2 0.3 5e-24 85.2 0.3 2.3 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGC30572.1 - 1.7e-07 30.8 1.0 0.0059 15.9 0.2 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC30572.1 - 3e-05 24.2 0.4 7.2e-05 22.9 0.4 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGC30572.1 - 0.0026 16.9 0.4 0.0044 16.1 0.4 1.3 1 0 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.12 EGC30572.1 - 0.0063 15.6 0.2 0.018 14.1 0.2 1.7 1 1 0 1 1 1 1 Lycopene cyclase protein Amino_oxidase PF01593.24 EGC30572.1 - 0.0082 15.5 0.1 0.18 11.1 0.0 2.4 2 1 0 2 2 2 1 Flavin containing amine oxidoreductase Pyr_redox PF00070.27 EGC30572.1 - 0.0084 16.6 1.3 0.22 12.1 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC30572.1 - 0.0089 15.3 0.4 1.6 7.9 0.3 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGC30572.1 - 0.13 11.9 0.4 0.68 9.5 0.3 2.0 2 0 0 2 2 2 0 FAD dependent oxidoreductase ADH_zinc_N_2 PF13602.6 EGC30574.1 - 0.018 16.1 0.0 0.036 15.1 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase KR PF08659.10 EGC30574.1 - 0.026 14.4 0.0 0.046 13.6 0.0 1.4 1 0 0 1 1 1 0 KR domain DMA PF03474.14 EGC30574.1 - 0.085 12.5 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 DMRTA motif PAT1 PF09770.9 EGC30575.1 - 0.014 13.7 20.4 0.016 13.5 20.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLDc_N PF13396.6 EGC30575.1 - 0.87 9.6 3.8 1.3 9.1 3.8 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal FeoB_associated PF12669.7 EGC30575.1 - 4.9 7.6 11.5 9.4 6.7 11.5 1.5 1 1 0 1 1 1 0 FeoB-associated Cys-rich membrane protein WD40_4 PF16300.5 EGC30576.1 - 0.011 15.6 0.1 0.025 14.5 0.1 1.6 1 1 1 2 2 2 0 Type of WD40 repeat DNase_II PF03265.15 EGC30577.1 - 1.2e-29 103.7 19.7 1.8e-25 89.9 6.4 2.7 2 1 1 3 3 3 2 Deoxyribonuclease II SAP PF02037.27 EGC30578.1 - 0.0001 22.0 0.0 0.00033 20.3 0.0 1.9 2 0 0 2 2 2 1 SAP domain ORC6 PF05460.13 EGC30578.1 - 0.092 12.0 3.5 0.2 10.9 3.5 1.5 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Thioredoxin_3 PF13192.6 EGC30579.1 - 0.16 12.0 0.0 0.79 9.8 0.0 2.2 1 0 0 1 1 1 0 Thioredoxin domain bZIP_1 PF00170.21 EGC30580.1 - 9.3e-14 51.3 8.9 9.3e-14 51.3 8.9 1.9 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC30580.1 - 2.2e-11 43.7 6.8 2.2e-11 43.7 6.8 2.2 2 0 0 2 2 2 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGC30580.1 - 2.7e-05 24.6 5.7 2.7e-05 24.6 5.7 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Menin PF05053.13 EGC30580.1 - 0.3 9.4 8.6 0.34 9.2 8.6 1.1 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGC30580.1 - 3.5 6.3 6.3 4.3 6.0 6.3 1.3 1 0 0 1 1 1 0 Presenilin DUF4407 PF14362.6 EGC30580.1 - 4.6 6.5 8.7 5.8 6.2 8.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SNRNP27 PF08648.12 EGC30581.1 - 5.6e-14 51.9 5.6 5.6e-14 51.9 5.6 3.4 3 0 0 3 3 3 1 U4/U6.U5 small nuclear ribonucleoproteins Peptidase_A25 PF03418.14 EGC30581.1 - 0.019 13.8 4.4 0.033 13.1 4.4 1.3 1 0 0 1 1 1 0 Germination protease NAD_binding_6 PF08030.12 EGC30582.1 - 1.9e-35 122.3 0.2 3.2e-35 121.6 0.2 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGC30582.1 - 2.5e-24 85.8 3.9 2.5e-24 85.8 3.9 2.1 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGC30582.1 - 5e-23 81.3 0.1 4.2e-22 78.3 0.0 2.6 2 0 0 2 2 2 1 FAD-binding domain FAD_binding_6 PF00970.24 EGC30582.1 - 0.0043 17.4 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGC30582.1 - 0.0076 16.9 0.0 0.027 15.1 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Nnf1 PF03980.14 EGC30583.1 - 5.2e-17 62.2 1.3 9.4e-17 61.4 1.3 1.4 1 0 0 1 1 1 1 Nnf1 SurA_N_3 PF13624.6 EGC30583.1 - 0.014 15.2 2.1 0.025 14.3 1.0 1.9 2 0 0 2 2 2 0 SurA N-terminal domain RBFA PF02033.18 EGC30583.1 - 0.036 14.5 1.3 0.061 13.8 1.3 1.6 1 1 0 1 1 1 0 Ribosome-binding factor A cNMP_binding PF00027.29 EGC30584.1 - 4e-45 151.8 0.0 8.1e-22 77.1 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 7TMR-HDED PF07697.11 EGC30584.1 - 0.014 15.5 1.8 0.79 9.8 0.5 2.7 2 1 0 2 2 2 0 7TM-HD extracellular Actin PF00022.19 EGC30585.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin GATA PF00320.27 EGC30586.1 - 1.2e-08 34.4 1.5 3.6e-08 32.9 1.5 1.9 1 0 0 1 1 1 1 GATA zinc finger DUF3439 PF11921.8 EGC30586.1 - 0.22 11.5 8.0 0.11 12.4 5.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Helicase_C PF00271.31 EGC30587.1 - 4.1e-22 78.6 1.6 4.3e-20 72.1 0.1 3.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC30587.1 - 1.7e-21 76.8 0.0 1.3e-20 73.9 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGC30587.1 - 3e-11 43.9 1.9 3e-11 43.9 1.9 2.6 2 0 0 2 2 2 1 RecQ zinc-binding D_CNTX PF17492.2 EGC30587.1 - 0.14 12.3 0.9 0.36 11.1 0.9 1.6 1 0 0 1 1 1 0 Delta Ctenitoxins 2OG-FeII_Oxy_2 PF13532.6 EGC30588.1 - 0.15 12.2 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily DUF3785 PF12653.7 EGC30589.1 - 0.64 10.1 5.3 0.45 10.6 2.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3785) Collectrin PF16959.5 EGC30590.1 - 0.44 10.3 4.0 0.37 10.6 1.3 2.0 1 1 0 2 2 2 0 Renal amino acid transporter DUF2340 PF10209.9 EGC30591.1 - 2.2e-40 137.9 1.3 2.5e-40 137.7 1.3 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) Band_7 PF01145.25 EGC30592.1 - 1.4e-31 109.9 3.6 1.9e-31 109.5 3.6 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0158 PF03682.13 EGC30592.1 - 0.0059 16.6 0.3 0.013 15.5 0.2 1.6 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0158) Band_7_1 PF13421.6 EGC30592.1 - 0.024 14.4 0.3 0.039 13.6 0.3 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family DUF3361 PF11841.8 EGC30593.1 - 0.0017 18.3 10.1 0.88 9.5 0.9 3.8 2 1 1 3 3 3 3 Domain of unknown function (DUF3361) Pyr_redox_2 PF07992.14 EGC30594.1 - 2.9e-42 144.9 0.1 4e-42 144.4 0.1 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC30594.1 - 2.5e-16 60.0 0.5 3.2e-09 37.2 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC30594.1 - 4e-11 42.7 1.0 3e-06 26.7 0.6 2.3 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGC30594.1 - 2.8e-07 30.1 0.0 0.0021 17.4 0.0 2.6 2 0 0 2 2 2 2 FAD binding domain K_oxygenase PF13434.6 EGC30594.1 - 1.3e-05 24.5 0.1 0.003 16.8 0.0 2.6 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGC30594.1 - 1.4e-05 25.1 0.1 1.4 8.9 0.0 4.0 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.6 EGC30594.1 - 3.6e-05 24.2 1.9 0.055 13.9 0.0 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.14 EGC30594.1 - 6.7e-05 21.9 0.1 0.16 10.8 0.0 3.0 4 0 0 4 4 4 2 Tryptophan halogenase Shikimate_DH PF01488.20 EGC30594.1 - 0.00011 22.2 0.0 0.036 14.1 0.0 2.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGC30594.1 - 0.00013 22.2 0.1 0.59 10.4 0.0 3.0 3 0 0 3 3 3 2 Saccharopine dehydrogenase NADP binding domain NAD_binding_8 PF13450.6 EGC30594.1 - 0.00022 21.4 0.1 0.011 16.0 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGC30594.1 - 0.00055 19.6 0.5 0.13 11.8 0.0 2.9 3 0 0 3 3 3 1 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGC30594.1 - 0.00072 18.9 0.0 0.3 10.3 0.0 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase GIDA PF01134.22 EGC30594.1 - 0.0011 18.2 5.4 0.18 10.8 0.0 4.2 2 1 1 4 4 4 1 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGC30594.1 - 0.0014 17.9 1.0 0.098 11.9 0.0 2.6 2 1 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.18 EGC30594.1 - 0.0016 18.7 1.9 0.86 9.9 0.1 3.1 4 0 0 4 4 3 1 TrkA-N domain Thi4 PF01946.17 EGC30594.1 - 0.0017 17.6 0.1 0.22 10.7 0.0 2.5 2 0 0 2 2 2 1 Thi4 family IlvN PF07991.12 EGC30594.1 - 0.005 16.4 0.1 0.68 9.5 0.0 2.6 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Lycopene_cycl PF05834.12 EGC30594.1 - 0.01 14.9 0.0 6.7 5.6 0.0 3.3 3 1 1 4 4 4 0 Lycopene cyclase protein DUF2024 PF09630.10 EGC30594.1 - 0.03 14.2 0.3 0.52 10.2 0.0 2.8 3 0 0 3 3 2 0 Domain of unknown function (DUF2024) HI0933_like PF03486.14 EGC30594.1 - 0.046 12.4 5.8 0.46 9.1 0.0 3.9 3 1 2 5 5 5 0 HI0933-like protein TPALS PF18178.1 EGC30594.1 - 0.058 12.8 0.1 1.7 8.0 0.1 2.9 2 1 2 4 4 4 0 TIR- and PNP-associating SLOG family AA_kinase PF00696.28 EGC30594.1 - 0.059 13.0 0.0 0.24 11.0 0.0 2.1 1 1 0 1 1 1 0 Amino acid kinase family ThiF PF00899.21 EGC30594.1 - 0.061 12.7 0.1 14 5.0 0.0 2.6 3 0 0 3 3 3 0 ThiF family FAD_binding_2 PF00890.24 EGC30594.1 - 0.072 12.1 0.0 0.35 9.9 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Semialdhyde_dh PF01118.24 EGC30594.1 - 0.14 12.6 0.5 1.2 9.6 0.0 2.7 4 0 0 4 4 3 0 Semialdehyde dehydrogenase, NAD binding domain PglD_N PF17836.1 EGC30594.1 - 0.31 11.7 1.8 17 6.2 0.0 3.7 4 0 0 4 4 3 0 PglD N-terminal domain DUF3496 PF12001.8 EGC30595.1 - 0.013 15.8 2.6 0.013 15.8 2.6 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3496) DEC-1_N PF04625.13 EGC30595.1 - 0.014 14.5 10.2 0.025 13.6 10.2 1.4 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Goodbye PF17109.5 EGC30595.1 - 0.57 10.6 2.7 0.94 9.9 0.1 2.4 2 0 0 2 2 2 0 fungal STAND N-terminal Goodbye domain FlaC_arch PF05377.11 EGC30595.1 - 2.7 8.5 11.2 0.079 13.4 2.5 2.5 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) RhoGEF PF00621.20 EGC30596.1 - 3.4e-47 161.1 14.6 6.2e-47 160.2 9.6 3.3 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGC30596.1 - 0.00088 19.8 0.1 0.003 18.0 0.1 2.0 1 0 0 1 1 1 1 PH domain Sod_Fe_N PF00081.22 EGC30596.1 - 1.4 9.4 11.9 0.36 11.3 0.3 4.0 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain DUF3899 PF13038.6 EGC30596.1 - 3.1 8.3 7.1 2.6 8.6 0.3 4.1 4 0 0 4 4 4 0 Domain of unknown function (DUF3899) Ribosomal_L18A PF01775.17 EGC30597.1 - 5.1e-49 165.4 0.8 6.9e-49 165.0 0.8 1.2 1 0 0 1 1 1 1 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A Metallophos PF00149.28 EGC30599.1 - 2e-08 35.0 1.4 2e-08 35.0 1.4 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase ABC2_membrane_3 PF12698.7 EGC30600.1 - 3.5e-52 177.7 72.5 3.7e-31 108.5 33.2 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGC30600.1 - 1.1e-49 168.4 0.3 7.5e-24 84.8 0.1 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC30600.1 - 7.2e-17 62.1 0.0 4e-06 26.9 0.0 4.9 4 0 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC30600.1 - 7.8e-07 28.7 0.2 0.71 9.3 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain SbcCD_C PF13558.6 EGC30600.1 - 0.0026 18.0 0.1 1.4 9.2 0.0 3.6 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.22 EGC30600.1 - 0.0029 17.3 0.6 0.87 9.2 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGC30600.1 - 0.0074 16.0 1.8 0.057 13.2 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA PF00004.29 EGC30600.1 - 0.027 14.9 0.1 1.3 9.4 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_23 PF13476.6 EGC30600.1 - 0.075 13.5 8.7 0.5 10.8 0.1 3.5 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGC30600.1 - 0.093 12.6 0.7 3.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGC30600.1 - 0.16 12.4 0.0 25 5.2 0.0 2.3 2 0 0 2 2 2 0 AAA ATPase domain AC_N PF16214.5 EGC30600.1 - 2.4 7.2 4.8 4.4 6.3 4.8 1.3 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region YmcE_antitoxin PF15939.5 EGC30600.1 - 3.8 7.7 6.6 0.83 9.9 0.1 3.4 4 0 0 4 4 4 0 Putative antitoxin of bacterial toxin-antitoxin system 1-cysPrx_C PF10417.9 EGC30601.1 - 0.48 10.3 2.4 12 5.8 0.0 2.4 3 0 0 3 3 3 0 C-terminal domain of 1-Cys peroxiredoxin Brr6_like_C_C PF10104.9 EGC30602.1 - 0.12 12.1 1.1 0.16 11.8 1.1 1.1 1 0 0 1 1 1 0 Di-sulfide bridge nucleocytoplasmic transport domain WD40 PF00400.32 EGC30603.1 - 6.4e-33 112.3 4.2 2.2e-06 28.3 0.0 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30603.1 - 8.5e-16 58.0 0.0 0.0059 16.9 0.0 5.4 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC30603.1 - 5.2e-07 28.9 1.1 0.16 10.9 0.1 3.8 1 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Cytochrom_D1 PF02239.16 EGC30603.1 - 2.8e-06 26.1 0.0 0.0001 21.0 0.0 2.4 2 1 1 3 3 3 1 Cytochrome D1 heme domain CSTF1_dimer PF16699.5 EGC30603.1 - 0.00012 21.8 0.0 0.00025 20.8 0.0 1.5 1 0 0 1 1 1 1 Cleavage stimulation factor subunit 1, dimerisation domain UQ_con PF00179.26 EGC30604.1 - 2.1e-47 160.3 0.1 2.5e-47 160.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGC30604.1 - 1.1e-05 25.2 0.0 1.8e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGC30604.1 - 0.00098 19.4 0.3 0.0012 19.1 0.2 1.4 1 1 0 1 1 1 1 RWD domain PI3_PI4_kinase PF00454.27 EGC30605.1 - 4e-58 197.2 3.4 7.8e-58 196.2 0.1 2.9 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC30605.1 - 1.4e-57 194.1 0.9 4.1e-57 192.6 0.9 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_rbd PF00794.18 EGC30605.1 - 6.5e-27 93.8 0.2 1.6e-25 89.4 0.0 2.8 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.24 EGC30605.1 - 1.3e-15 57.5 0.1 1.3e-15 57.5 0.1 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DUF4940 PF16298.5 EGC30606.1 - 0.012 15.2 0.3 0.019 14.7 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4940) tRNA-synt_1c_C PF03950.18 EGC30607.1 - 0.061 13.2 1.4 0.13 12.2 0.7 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PHD PF00628.29 EGC30609.1 - 4.8e-05 23.2 20.7 0.00033 20.5 12.1 3.2 2 1 1 3 3 3 2 PHD-finger DUF2180 PF09947.9 EGC30609.1 - 0.044 13.8 0.1 0.044 13.8 0.1 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2180) DUF282 PF03380.14 EGC30609.1 - 0.47 10.4 3.7 1.6 8.7 3.7 2.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 PHD_2 PF13831.6 EGC30609.1 - 0.93 9.1 15.6 0.012 15.1 5.0 2.9 2 1 1 3 3 3 0 PHD-finger PHD_4 PF16866.5 EGC30609.1 - 3.8 7.7 16.3 2.1 8.5 9.4 3.3 2 1 0 2 2 2 0 PHD-finger NBD94 PF16830.5 EGC30609.1 - 8.6 6.8 14.2 0.086 13.2 4.1 2.8 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH Motile_Sperm PF00635.26 EGC30610.1 - 7.2e-22 77.3 0.4 7.2e-22 77.3 0.4 2.1 2 1 0 2 2 2 1 MSP (Major sperm protein) domain AKNA PF12443.8 EGC30610.1 - 0.33 11.6 6.1 9.7 6.9 1.7 2.5 2 0 0 2 2 2 0 AT-hook-containing transcription factor Menin PF05053.13 EGC30610.1 - 0.5 8.7 6.9 0.61 8.4 6.9 1.1 1 0 0 1 1 1 0 Menin EVI2A PF05399.11 EGC30610.1 - 2 8.0 17.6 0.41 10.2 13.2 1.9 1 1 1 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) ALMT PF11744.8 EGC30610.1 - 3.1 6.5 6.7 4 6.2 6.7 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter FAM76 PF16046.5 EGC30610.1 - 8.7 5.6 8.7 13 5.0 8.7 1.2 1 0 0 1 1 1 0 FAM76 protein Coiled PF05710.12 EGC30612.1 - 0.0096 16.7 3.6 0.01 16.6 3.6 1.1 1 0 0 1 1 1 1 Coiled coil Cir_Bir_Yir PF06022.11 EGC30612.1 - 0.016 14.7 1.8 0.019 14.5 1.8 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir Peptidase_M48_N PF16491.5 EGC30614.1 - 0.018 15.0 0.7 0.027 14.4 0.7 1.2 1 0 0 1 1 1 0 CAAX prenyl protease N-terminal, five membrane helices SET PF00856.28 EGC30616.1 - 7.3e-17 62.3 0.1 7.3e-17 62.3 0.1 3.0 3 1 0 3 3 3 1 SET domain TPR_2 PF07719.17 EGC30616.1 - 0.001 19.0 4.0 0.016 15.3 0.5 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC30616.1 - 0.03 14.1 10.1 0.033 14.0 0.8 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Rhodanese_C PF12368.8 EGC30616.1 - 0.17 12.3 15.9 0.093 13.1 6.2 3.2 2 0 0 2 2 2 0 Rhodanase C-terminal Tim54 PF11711.8 EGC30618.1 - 0.063 12.1 0.6 0.063 12.1 0.6 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Secretin_N_2 PF07655.13 EGC30618.1 - 0.95 10.0 15.5 0.43 11.1 13.4 1.5 2 0 0 2 2 2 0 Secretin N-terminal domain Corazonin PF17308.2 EGC30618.1 - 2.8 8.3 14.8 8.4 6.8 12.0 2.1 2 0 0 2 2 2 0 Pro-corazonin NST1 PF13945.6 EGC30618.1 - 4 7.5 15.7 6.3 6.9 15.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator FNIP PF05725.12 EGC30619.1 - 1.1e-105 345.6 54.5 7.1e-16 58.1 1.0 8.9 3 1 1 9 9 9 8 FNIP Repeat MCM_OB PF17207.3 EGC30619.1 - 6.1e-05 22.9 0.0 39 4.1 0.0 6.2 3 3 2 8 8 8 1 MCM OB domain Adap_comp_sub PF00928.21 EGC30620.1 - 3.8e-22 78.9 1.8 5.6e-22 78.4 1.8 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGC30620.1 - 2.7e-08 33.9 0.3 4.6e-08 33.1 0.3 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ints3 PF10189.9 EGC30621.1 - 6.6e-90 300.3 0.3 1.1e-89 299.6 0.3 1.3 1 0 0 1 1 1 1 Integrator complex subunit 3 Hyccin PF09790.9 EGC30621.1 - 0.0049 16.0 1.1 0.092 11.8 0.2 2.7 2 0 0 2 2 2 1 Hyccin DUF963 PF06131.11 EGC30621.1 - 1.2 8.6 7.2 4.1 6.9 1.3 2.6 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) WD40 PF00400.32 EGC30623.1 - 2.4e-22 78.8 3.8 1.9e-07 31.6 0.1 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30623.1 - 1.6e-06 28.3 0.0 0.66 10.3 0.0 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC30623.1 - 0.031 13.2 0.0 0.61 9.0 0.0 2.5 2 0 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGC30623.1 - 0.13 12.3 0.1 0.52 10.3 0.1 2.1 1 0 0 1 1 1 0 WD40-like Beta Propeller Repeat Ras PF00071.22 EGC30624.1 - 3e-46 157.0 0.0 3.5e-46 156.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30624.1 - 1.7e-21 76.6 0.0 2.4e-21 76.1 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30624.1 - 1.6e-08 34.2 0.0 2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC30624.1 - 0.064 13.3 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 EGC30624.1 - 0.082 12.4 0.0 0.2 11.1 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region MCM PF00493.23 EGC30624.1 - 0.17 10.9 0.1 0.55 9.3 0.0 1.8 2 0 0 2 2 2 0 MCM P-loop domain zf-C3HC4_3 PF13920.6 EGC30625.1 - 2.6e-12 46.4 12.0 4.4e-12 45.7 12.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC30625.1 - 0.00038 20.2 12.4 0.00074 19.3 12.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC30625.1 - 0.00072 19.8 12.7 0.0014 18.9 12.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.14 EGC30625.1 - 0.0085 15.7 9.4 0.0085 15.7 9.4 1.7 2 0 0 2 2 2 1 P-11 zinc finger DUF5627 PF18620.1 EGC30625.1 - 0.018 14.9 8.3 0.053 13.4 8.3 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5627) zf-RING_5 PF14634.6 EGC30625.1 - 0.032 14.2 11.0 0.062 13.3 11.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DUF3439 PF11921.8 EGC30625.1 - 0.66 10.0 15.0 0.059 13.3 9.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC30625.1 - 0.69 9.9 20.4 0.03 14.3 9.3 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-RING_4 PF14570.6 EGC30625.1 - 2.1 8.2 8.8 4.3 7.2 8.8 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.6 EGC30625.1 - 2.7 7.9 12.0 6.6 6.7 12.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) SSP160 PF06933.11 EGC30625.1 - 3.5 5.7 22.6 0.0097 14.2 9.3 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Ras PF00071.22 EGC30626.1 - 4.1e-59 198.8 0.0 4.8e-59 198.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30626.1 - 3.9e-35 120.7 0.1 5.2e-35 120.3 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30626.1 - 6e-18 64.9 0.0 7.8e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC30626.1 - 1.3e-07 31.7 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC30626.1 - 2.6e-05 23.8 0.0 0.00023 20.8 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGC30626.1 - 6.2e-05 22.5 0.0 7.2e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.17 EGC30626.1 - 6.4e-05 22.9 0.0 0.0013 18.6 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein RsgA_GTPase PF03193.16 EGC30626.1 - 0.0019 18.2 0.0 0.16 11.9 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGC30626.1 - 0.0058 16.1 0.0 0.009 15.5 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGC30626.1 - 0.019 14.7 0.0 0.27 11.0 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGC30626.1 - 0.023 14.2 0.0 0.31 10.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 EGC30626.1 - 0.11 12.9 0.1 0.19 12.1 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain DNase_II PF03265.15 EGC30627.1 - 1e-25 90.7 24.7 5.1e-24 85.2 9.7 3.3 4 0 0 4 4 4 2 Deoxyribonuclease II PH PF00169.29 EGC30628.1 - 1.8e-19 70.2 4.8 4.7e-19 68.9 4.8 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC30628.1 - 8.7e-06 26.1 12.6 3.1e-05 24.3 4.8 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.6 EGC30628.1 - 2.5e-05 24.3 2.7 5.4e-05 23.2 2.7 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGC30628.1 - 0.00015 22.0 0.4 0.00029 21.1 0.4 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_13 PF16652.5 EGC30628.1 - 0.00064 19.6 1.2 0.0011 18.8 0.1 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_16 PF17838.1 EGC30628.1 - 0.0036 17.1 0.2 0.0075 16.1 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGC30628.1 - 0.004 17.5 0.4 0.017 15.5 0.4 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain PH_2 PF08458.10 EGC30628.1 - 0.015 15.6 0.2 0.03 14.7 0.2 1.5 1 0 0 1 1 1 0 Plant pleckstrin homology-like region DUF4894 PF16235.5 EGC30628.1 - 0.069 13.5 0.3 0.12 12.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4894) PH_15 PF17339.2 EGC30628.1 - 0.14 12.1 1.2 0.39 10.7 1.2 1.8 1 1 0 1 1 1 0 PH domain DUF155 PF02582.14 EGC30629.1 - 1.2e-29 103.6 0.6 2.1e-29 102.9 0.6 1.4 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Catalase PF00199.19 EGC30630.1 - 5.3e-197 654.5 0.2 6.2e-197 654.3 0.2 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.12 EGC30630.1 - 3.3e-20 72.0 0.0 7.9e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive EF-hand_1 PF00036.32 EGC30631.1 - 5.2e-22 75.7 3.9 4.2e-06 25.9 0.2 4.3 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGC30631.1 - 1.3e-20 71.5 5.0 9.7e-06 25.1 0.0 4.5 4 2 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGC30631.1 - 4.2e-19 67.1 8.2 2.8e-06 26.5 0.5 3.7 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGC30631.1 - 2.7e-17 62.9 6.9 3.1e-12 46.8 0.8 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC30631.1 - 3e-12 46.2 4.2 0.0058 16.4 0.2 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.7 EGC30631.1 - 1.6e-05 24.8 1.4 0.092 12.7 0.1 3.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGC30631.1 - 0.00037 20.8 3.7 2.4 8.5 0.1 3.7 2 2 1 3 3 3 1 Secreted protein acidic and rich in cysteine Ca binding region Dockerin_1 PF00404.18 EGC30631.1 - 0.00084 19.5 2.0 2.4 8.4 0.2 3.3 2 1 1 3 3 3 2 Dockerin type I domain EF-hand_9 PF14658.6 EGC30631.1 - 0.009 16.3 0.0 0.032 14.5 0.0 2.0 2 0 0 2 2 1 1 EF-hand domain EF-hand_11 PF08976.11 EGC30631.1 - 0.034 15.0 0.1 16 6.5 0.0 2.6 2 1 0 2 2 2 0 EF-hand domain TerB_C PF15615.6 EGC30631.1 - 0.061 13.6 0.2 0.12 12.7 0.2 1.5 1 0 0 1 1 1 0 TerB-C domain TMF_TATA_bd PF12325.8 EGC30632.1 - 2.4e-30 105.1 11.2 2.4e-30 105.1 11.2 8.3 3 1 6 10 10 10 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.8 EGC30632.1 - 2.3e-11 43.5 13.4 2.3e-11 43.5 13.4 9.8 6 2 3 10 10 10 3 TATA element modulatory factor 1 DNA binding ATG16 PF08614.11 EGC30632.1 - 0.00064 20.0 33.1 0.00064 20.0 33.1 6.6 1 1 4 5 5 5 1 Autophagy protein 16 (ATG16) CENP-F_leu_zip PF10473.9 EGC30632.1 - 0.001 19.1 14.0 0.001 19.1 14.0 8.4 4 1 3 8 8 8 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EGC30632.1 - 0.013 16.1 8.8 0.013 16.1 8.8 8.4 3 2 4 7 7 7 0 Apg6 coiled-coil region DivIC PF04977.15 EGC30632.1 - 0.015 15.1 1.3 0.015 15.1 1.3 10.2 6 4 3 10 10 10 0 Septum formation initiator DUF4200 PF13863.6 EGC30632.1 - 0.033 14.6 0.8 0.033 14.6 0.8 10.4 4 2 6 11 11 11 0 Domain of unknown function (DUF4200) Hemocyanin_N PF03722.14 EGC30632.1 - 1.3 9.6 15.3 2.4 8.7 1.5 4.5 3 0 0 3 3 3 0 Hemocyanin, all-alpha domain AAA_11 PF13086.6 EGC30633.1 - 3.8e-77 259.6 13.0 9.9e-39 133.7 0.9 3.5 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 EGC30633.1 - 4.7e-59 199.4 1.0 6.5e-58 195.6 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_30 PF13604.6 EGC30633.1 - 6.1e-09 35.9 4.0 0.0009 19.0 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.6 EGC30633.1 - 8.6e-08 32.6 0.1 0.026 14.9 0.0 3.0 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.18 EGC30633.1 - 2.3e-06 27.6 0.7 0.012 15.4 0.0 3.7 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGC30633.1 - 0.0037 16.8 0.2 0.13 11.7 0.0 2.5 2 0 0 2 2 2 1 PhoH-like protein AAA_16 PF13191.6 EGC30633.1 - 0.024 15.0 0.0 0.09 13.2 0.0 2.0 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGC30633.1 - 0.05 13.9 0.4 1 9.6 0.0 3.2 3 1 0 3 3 3 0 AAA domain Mg_chelatase PF01078.21 EGC30633.1 - 0.056 12.8 0.0 0.14 11.5 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGC30633.1 - 0.071 12.8 0.0 0.23 11.2 0.0 1.8 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_pol_Rpc4 PF05132.14 EGC30633.1 - 1.2 9.5 9.5 80 3.6 9.0 2.7 2 0 0 2 2 2 0 RNA polymerase III RPC4 NARP1 PF12569.8 EGC30633.1 - 4.3 6.1 20.0 7.2 5.4 20.0 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.17 EGC30633.1 - 4.4 7.4 11.1 38 4.3 7.1 2.8 3 0 0 3 3 3 0 DDHD domain PIEZO PF15917.5 EGC30633.1 - 6.8 6.1 16.3 15 5.0 10.9 2.5 2 0 0 2 2 2 0 Piezo Presenilin PF01080.17 EGC30633.1 - 8.4 5.0 12.7 18 4.0 12.7 1.5 1 0 0 1 1 1 0 Presenilin DUF4228 PF14009.6 EGC30633.1 - 9.3 6.6 8.6 1.6 9.1 4.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4228) DNA_pol_A_exo1 PF01612.20 EGC30635.1 - 7.5e-07 29.0 0.1 1.4e-06 28.2 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease Svs_4_5_6 PF17381.2 EGC30635.1 - 3.3 8.8 6.2 3.8 8.6 1.0 2.3 2 0 0 2 2 2 0 Seminal vesicle secretory proteins 4/5/6 PARP PF00644.20 EGC30636.1 - 4.2e-13 49.3 11.8 4.2e-13 49.3 11.8 3.0 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UIM PF02809.20 EGC30636.1 - 0.024 14.5 16.1 0.17 11.9 1.0 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif UBX PF00789.20 EGC30637.1 - 9.4e-13 48.2 0.0 2.7e-12 46.7 0.0 1.8 1 0 0 1 1 1 1 UBX domain UIM PF02809.20 EGC30637.1 - 1.6 8.9 11.0 0.21 11.6 1.0 2.9 2 0 0 2 2 2 0 Ubiquitin interaction motif Helicase_C PF00271.31 EGC30638.1 - 1e-12 48.4 0.2 4e-12 46.5 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Colicin_V PF02674.16 EGC30638.1 - 0.03 14.3 3.9 0.2 11.6 0.6 2.6 2 0 0 2 2 2 0 Colicin V production protein Isochorismatase PF00857.20 EGC30639.1 - 1.4e-32 113.3 0.0 1.6e-32 113.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Endonuclease_NS PF01223.23 EGC30640.1 - 4.3e-46 157.5 2.3 6.8e-46 156.9 2.3 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Mito_carr PF00153.27 EGC30643.1 - 0.097 12.6 0.1 0.1 12.5 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial carrier protein DUF1910 PF08928.10 EGC30645.1 - 0.3 11.1 7.3 1.4 9.0 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) AFP_2 PF18815.1 EGC30645.1 - 1.8 8.9 4.9 0.93 9.8 1.2 2.3 2 0 0 2 2 2 0 Bacterial antifreeze protein repeat BRCT_3 PF18428.1 EGC30647.1 - 2.3e-17 62.9 0.0 7.4e-17 61.3 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC30647.1 - 4e-09 36.8 7.6 0.0005 20.4 0.1 3.3 3 0 0 3 3 3 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC30647.1 - 2.6e-08 34.1 8.3 0.0023 18.3 0.1 4.2 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain FAD_binding_1 PF00667.20 EGC30648.1 - 1.2e-11 44.7 0.1 1.4e-11 44.4 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_S24 PF00717.23 EGC30648.1 - 0.044 13.7 0.0 0.47 10.5 0.0 2.3 1 1 1 2 2 2 0 Peptidase S24-like Cadherin_C PF01049.17 EGC30648.1 - 0.062 13.6 0.1 0.066 13.6 0.1 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region GpcrRhopsn4 PF10192.9 EGC30649.1 - 2.3e-40 138.6 36.3 2.3e-40 138.6 36.3 2.1 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain DUF2839 PF10999.8 EGC30649.1 - 9 6.7 5.8 2.6 8.5 2.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Glyco_hydro_47 PF01532.20 EGC30650.1 - 2.6e-137 458.5 0.3 3.5e-137 458.0 0.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 EGC30650.1 - 0.0007 18.9 0.1 1.2 8.4 0.0 3.7 4 0 0 4 4 4 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) HNOB PF07700.15 EGC30650.1 - 0.084 12.8 0.8 3.7 7.5 0.1 2.9 3 0 0 3 3 3 0 Haem-NO-binding CBM49 PF09478.10 EGC30651.1 - 1.8e-21 76.2 4.4 3.3e-21 75.4 4.4 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGC30651.1 - 0.024 14.9 3.5 0.024 14.9 3.5 2.0 3 0 0 3 3 3 0 Cellulose binding domain RhoGEF PF00621.20 EGC30652.1 - 4.2e-36 124.9 2.7 4.2e-36 124.9 2.7 2.5 3 0 0 3 3 3 1 RhoGEF domain PH_10 PF15411.6 EGC30652.1 - 0.0004 20.6 0.0 0.0004 20.6 0.0 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain PH PF00169.29 EGC30652.1 - 0.0034 17.8 3.8 2.2 8.8 0.2 4.0 3 0 0 3 3 3 2 PH domain IQ PF00612.27 EGC30652.1 - 0.014 15.1 1.0 0.028 14.2 1.0 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif PDDEXK_7 PF04411.12 EGC30652.1 - 0.047 13.7 0.3 0.15 12.0 0.3 1.9 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily DUF1647 PF07801.11 EGC30653.1 - 0.56 10.0 3.7 0.23 11.2 1.4 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1647) SdrD_B PF17210.3 EGC30654.1 - 3.2e-232 755.2 80.3 1.2e-22 80.2 1.8 16.6 16 0 0 16 16 16 16 SdrD B-like domain CarboxypepD_reg PF13620.6 EGC30654.1 - 3.1e-83 274.1 35.2 1.2e-08 35.1 0.2 16.8 16 0 0 16 16 16 16 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGC30654.1 - 7.3e-33 112.7 45.1 0.0012 19.1 0.0 15.3 16 0 0 16 16 16 10 Prealbumin-like fold domain CarbopepD_reg_2 PF13715.6 EGC30654.1 - 8.6e-31 105.8 45.1 0.00037 20.4 0.5 18.3 16 2 0 16 16 16 9 CarboxypepD_reg-like domain bMG3 PF11974.8 EGC30654.1 - 1.4e-13 50.8 0.0 0.027 14.5 0.0 8.8 8 0 0 8 8 8 2 Bacterial alpha-2-macroglobulin MG3 domain DUF2012 PF09430.10 EGC30654.1 - 5.9e-10 39.3 14.8 0.041 14.0 0.0 10.1 12 0 0 12 12 12 2 Protein of unknown function (DUF2012) Big_1 PF02369.16 EGC30654.1 - 2.5e-09 37.0 24.7 0.44 10.6 0.1 10.5 11 0 0 11 11 11 4 Bacterial Ig-like domain (group 1) fn3_3 PF14686.6 EGC30654.1 - 9.3e-07 28.5 19.2 0.21 11.4 0.1 8.9 10 0 0 10 10 10 2 Polysaccharide lyase family 4, domain II MetallophosN PF16371.5 EGC30654.1 - 2.6e-06 27.6 36.1 0.16 12.2 0.2 13.0 14 1 0 14 14 14 3 N terminal of Calcineurin-like phosphoesterase DUF4198 PF10670.9 EGC30654.1 - 0.0012 19.2 0.7 4.6 7.6 0.0 5.5 5 0 0 5 5 5 1 Domain of unknown function (DUF4198) Dioxygenase_C PF00775.21 EGC30654.1 - 0.048 13.1 12.3 41 3.5 0.0 8.5 11 0 0 11 11 11 0 Dioxygenase Invasin_D3 PF09134.10 EGC30654.1 - 0.58 10.5 14.2 4.8 7.6 0.0 6.6 7 0 0 7 7 7 0 Invasin, domain 3 VPS13_mid_rpt PF16910.5 EGC30655.1 - 1.9e-51 174.8 34.0 2.6e-45 154.7 13.0 7.7 5 1 0 5 5 5 3 Repeating coiled region of VPS13 VPS13 PF16908.5 EGC30655.1 - 4.1e-50 170.8 5.6 4.1e-50 170.8 5.6 6.8 6 0 0 6 6 6 1 Vacuolar sorting-associated protein 13, N-terminal SHR-BD PF06650.12 EGC30655.1 - 6.1e-45 153.7 5.3 6.1e-45 153.7 5.3 6.2 5 1 1 6 6 6 1 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_C PF16909.5 EGC30655.1 - 1.9e-30 105.9 2.7 1.9e-30 105.9 2.7 5.3 5 1 0 5 5 5 2 Vacuolar-sorting-associated 13 protein C-terminal Chorein_N PF12624.7 EGC30655.1 - 2.4e-25 88.9 0.4 2.4e-25 88.9 0.4 3.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGC30655.1 - 0.00015 22.0 0.0 0.00061 20.1 0.0 2.1 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain DUF3439 PF11921.8 EGC30655.1 - 2.7 8.0 5.8 1.3 9.0 2.8 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) ETRAMP PF09716.10 EGC30656.1 - 0.72 10.0 6.3 0.21 11.7 0.3 3.2 2 2 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3385 PF11865.8 EGC30656.1 - 4.4 7.2 10.1 2.7 7.9 5.5 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3385) PIP5K PF01504.18 EGC30657.1 - 2.3e-68 230.4 7.0 2.3e-68 230.4 7.0 2.5 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase TFIIA PF03153.13 EGC30657.1 - 0.1 12.6 37.4 0.048 13.7 32.3 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGC30657.1 - 1.1 7.4 29.3 2.1 6.5 29.3 1.4 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CPSF100_C PF13299.6 EGC30657.1 - 3.7 7.7 12.4 6.2 7.0 9.1 2.5 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal SLT PF01464.20 EGC30658.1 - 1.1e-08 34.7 0.0 1.9e-08 34.0 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGC30658.1 - 7.6e-05 23.0 5.8 0.00025 21.3 5.8 1.8 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family FNIP PF05725.12 EGC30659.1 - 3.2e-153 497.7 73.5 6.2e-16 58.3 0.2 11.5 4 3 9 15 15 15 15 FNIP Repeat Phage_min_tail PF05939.13 EGC30659.1 - 0.00014 22.2 0.1 22 5.5 0.0 7.1 3 3 5 8 8 8 1 Phage minor tail protein Keratin_assoc PF09775.9 EGC30659.1 - 0.0003 20.4 6.9 9.6 5.9 0.0 7.1 2 2 8 10 10 10 2 Keratinocyte-associated protein 2 LRR_1 PF00560.33 EGC30659.1 - 1.5 9.7 14.9 77 4.4 0.1 8.0 7 5 0 7 7 7 0 Leucine Rich Repeat FNIP PF05725.12 EGC30660.1 - 2.3e-108 354.1 55.5 5.5e-15 55.2 0.7 7.6 2 2 8 11 11 11 10 FNIP Repeat Phage_min_tail PF05939.13 EGC30660.1 - 0.15 12.4 0.0 27 5.2 0.0 4.1 3 1 2 5 5 5 0 Phage minor tail protein FNIP PF05725.12 EGC30661.1 - 2e-59 197.5 27.9 1.4e-13 50.8 0.4 6.2 4 1 1 6 6 6 6 FNIP Repeat FNIP PF05725.12 EGC30662.1 - 1e-14 54.4 4.6 5.4e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 FNIP Repeat BsuBI_PstI_RE PF06616.11 EGC30663.1 - 0.00036 19.8 0.2 0.00045 19.5 0.2 1.3 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain zf-RVT PF13966.6 EGC30663.1 - 0.037 14.7 0.0 0.064 14.0 0.0 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase FNIP PF05725.12 EGC30664.1 - 4.5e-165 535.7 68.7 2.5e-16 59.6 0.2 13.9 11 2 2 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.13 EGC30664.1 - 0.003 17.9 0.0 31 5.0 0.0 6.3 4 1 3 8 8 8 1 Phage minor tail protein FNIP PF05725.12 EGC30665.1 - 7.3e-208 672.6 113.6 2.4e-16 59.6 1.9 16.4 7 2 9 19 19 19 19 FNIP Repeat Phage_min_tail PF05939.13 EGC30665.1 - 0.00039 20.8 0.1 61 4.1 0.0 8.0 5 5 6 11 11 11 0 Phage minor tail protein LRR_1 PF00560.33 EGC30665.1 - 0.74 10.6 27.8 53 4.9 0.1 11.6 9 4 1 10 10 10 0 Leucine Rich Repeat HSP20 PF00011.21 EGC30666.1 - 1.3e-13 50.9 1.0 5.1e-07 29.8 0.0 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family NUFIP1 PF10453.9 EGC30666.1 - 0.0045 16.8 3.8 0.2 11.5 0.2 2.9 2 0 0 2 2 2 2 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) ArsA_HSP20 PF17886.1 EGC30666.1 - 0.0098 15.4 0.0 0.21 11.2 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Transferase PF02458.15 EGC30667.1 - 3.3e-11 42.5 0.1 4.4e-11 42.1 0.1 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 EGC30667.1 - 0.0018 17.1 0.0 0.003 16.3 0.0 1.4 1 0 0 1 1 1 1 Condensation domain Transferase PF02458.15 EGC30668.1 - 1.3e-10 40.6 0.0 1.8e-10 40.1 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 EGC30668.1 - 0.014 14.1 0.0 0.022 13.5 0.0 1.2 1 0 0 1 1 1 0 Condensation domain DUF4300 PF14133.6 EGC30669.1 - 0.00087 19.1 0.2 0.0012 18.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) DUF2417 PF10329.9 EGC30669.1 - 0.017 14.6 0.3 0.026 13.9 0.3 1.4 1 0 0 1 1 1 0 Region of unknown function (DUF2417) PA26 PF04636.13 EGC30670.1 - 0.41 9.5 6.9 0.55 9.1 6.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SR-25 PF10500.9 EGC30670.1 - 0.73 9.4 11.7 0.14 11.8 8.3 1.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Presenilin PF01080.17 EGC30670.1 - 1.4 7.6 7.7 1.6 7.4 7.7 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 EGC30671.1 - 8.1e-10 38.9 3.6 8.1e-10 38.9 3.6 4.8 4 1 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 EGC30671.1 - 2.4e-05 24.2 1.8 2.4e-05 24.2 1.8 5.0 4 1 0 4 4 4 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC30671.1 - 7.1e-05 22.5 2.2 7.1e-05 22.5 2.2 3.4 3 0 0 3 3 3 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGC30671.1 - 0.00012 22.0 0.4 0.00012 22.0 0.4 4.8 5 0 0 5 5 5 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC30671.1 - 0.00051 19.9 1.0 0.00051 19.9 1.0 4.6 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30671.1 - 0.00052 19.8 1.2 0.00052 19.8 1.2 5.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-CHY PF05495.12 EGC30671.1 - 0.006 17.1 2.4 0.006 17.1 2.4 3.4 2 1 1 3 3 3 1 CHY zinc finger zf-rbx1 PF12678.7 EGC30671.1 - 0.0061 16.8 4.4 0.0061 16.8 4.4 4.2 3 2 1 4 4 4 1 RING-H2 zinc finger domain Zn_ribbon_17 PF17120.5 EGC30671.1 - 0.0071 16.0 0.7 0.0071 16.0 0.7 4.6 5 0 0 5 5 5 1 Zinc-ribbon, C4HC2 type PEP_mutase PF13714.6 EGC30672.1 - 3.2e-55 187.2 0.1 3.6e-55 187.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.21 EGC30672.1 - 1.3e-15 56.9 0.1 1.8e-15 56.4 0.1 1.1 1 0 0 1 1 1 1 Isocitrate lyase family NanE PF04131.14 EGC30672.1 - 0.012 14.8 0.1 0.043 13.0 0.1 1.9 1 1 0 2 2 2 0 Putative N-acetylmannosamine-6-phosphate epimerase DUF4834 PF16118.5 EGC30673.1 - 0.0012 19.8 0.1 0.0029 18.5 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) Connexin PF00029.19 EGC30673.1 - 0.0053 16.5 0.0 0.0093 15.8 0.0 1.3 1 0 0 1 1 1 1 Connexin SHR3_chaperone PF08229.11 EGC30673.1 - 0.015 14.3 0.2 0.033 13.1 0.2 1.5 1 0 0 1 1 1 0 ER membrane protein SH3 EGF_2 PF07974.13 EGC30673.1 - 0.97 9.9 9.2 3 8.3 9.2 1.9 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGC30674.1 - 5.2e-05 23.2 1.0 0.0002 21.4 0.1 2.4 2 0 0 2 2 2 1 IPT/TIG domain DUF1947 PF09183.10 EGC30674.1 - 0.034 14.5 2.7 0.034 14.4 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) FNIP PF05725.12 EGC30675.1 - 1.8e-20 72.8 58.4 5.3e-05 23.3 3.3 10.8 6 3 5 11 11 11 11 FNIP Repeat zf-A20 PF01754.16 EGC30676.1 - 2.9e-10 39.9 8.0 2.9e-10 39.9 8.0 2.4 2 0 0 2 2 2 1 A20-like zinc finger zf-AN1 PF01428.16 EGC30676.1 - 3.5e-05 23.9 10.5 3.5e-05 23.9 10.5 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Pyr_redox_2 PF07992.14 EGC30677.1 - 2.8e-44 151.5 0.0 4.3e-44 150.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.6 EGC30677.1 - 2.2e-19 70.1 3.0 4e-11 43.4 0.0 3.2 2 1 1 3 3 3 2 Apoptosis-inducing factor, mitochondrion-associated, C-term NAD_binding_9 PF13454.6 EGC30677.1 - 4.2e-08 33.3 0.0 0.0012 18.9 0.0 3.5 2 1 1 3 3 3 2 FAD-NAD(P)-binding Pyr_redox PF00070.27 EGC30677.1 - 1.6e-06 28.6 0.1 1.8e-05 25.2 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC30677.1 - 8.5e-06 25.2 0.3 0.0018 17.6 0.0 2.4 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.24 EGC30677.1 - 0.00047 19.6 0.0 0.00062 19.2 0.0 1.4 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.14 EGC30677.1 - 0.0052 15.5 0.0 0.17 10.6 0.0 2.7 3 0 0 3 3 3 1 HI0933-like protein NAD_binding_7 PF13241.6 EGC30677.1 - 0.0056 17.1 0.0 0.079 13.4 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding Lipocalin_3 PF12702.7 EGC30677.1 - 0.0058 16.7 0.0 0.018 15.1 0.0 1.9 1 0 0 1 1 1 1 Lipocalin-like DAO PF01266.24 EGC30677.1 - 0.036 13.7 0.2 0.097 12.2 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF3530 PF12048.8 EGC30677.1 - 0.094 12.1 0.0 0.18 11.2 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3530) WD40 PF00400.32 EGC30678.1 - 2.8e-51 170.4 17.1 2.8e-09 37.4 0.5 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat TFIID_NTD2 PF04494.15 EGC30678.1 - 1.4e-44 151.4 2.0 3.2e-44 150.3 2.0 1.6 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit, NTD2 domain ANAPC4_WD40 PF12894.7 EGC30678.1 - 1.3e-12 47.8 0.0 0.0012 19.1 0.0 4.9 2 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC30678.1 - 7.7e-06 25.1 0.1 0.33 9.9 0.0 4.1 3 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGC30678.1 - 2.3e-05 23.9 0.1 1.3 8.3 0.1 4.7 4 1 1 5 5 5 2 WD40-like domain LisH PF08513.11 EGC30678.1 - 0.002 18.0 0.1 0.0059 16.5 0.1 1.9 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.16 EGC30678.1 - 0.035 12.6 0.0 0.064 11.8 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain SurA_N_2 PF13623.6 EGC30678.1 - 0.32 10.8 8.2 17 5.3 6.6 2.8 2 0 0 2 2 2 0 SurA N-terminal domain Roughex PF06020.11 EGC30678.1 - 3.6 6.6 7.6 11 5.1 7.6 1.7 1 0 0 1 1 1 0 Drosophila roughex protein Endotoxin_N PF03945.14 EGC30679.1 - 5.5e-23 81.8 8.1 5.5e-23 81.8 8.1 2.7 3 0 0 3 3 3 1 delta endotoxin, N-terminal domain PEN-2 PF10251.9 EGC30680.1 - 0.019 15.4 1.3 0.036 14.5 1.3 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Trefoil PF00088.18 EGC30680.1 - 0.063 13.2 1.6 0.078 12.9 0.6 1.7 2 0 0 2 2 2 0 Trefoil (P-type) domain DUF2207 PF09972.9 EGC30680.1 - 0.1 11.4 0.2 0.12 11.1 0.2 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Glyco_hydro_42M PF08532.10 EGC30681.1 - 1.7e-05 24.5 0.0 0.00016 21.2 0.0 2.1 2 0 0 2 2 2 1 Beta-galactosidase trimerisation domain zf-CCHC PF00098.23 EGC30681.1 - 0.00062 19.7 16.7 0.015 15.4 0.4 3.4 3 0 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGC30681.1 - 0.0083 15.8 6.1 0.99 9.2 0.8 2.8 2 0 0 2 2 2 2 Zinc knuckle zf-CCHC_3 PF13917.6 EGC30681.1 - 0.46 10.5 9.0 8.1 6.5 0.3 2.8 1 1 1 2 2 2 0 Zinc knuckle zf-C2H2_10 PF16588.5 EGC30681.1 - 1 9.2 9.3 0.045 13.5 0.6 2.4 2 0 0 2 2 2 0 C2H2 zinc-finger tRNA_edit PF04073.15 EGC30682.1 - 1.1e-05 25.5 0.0 2.1e-05 24.6 0.0 1.4 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain rve PF00665.26 EGC30682.1 - 0.012 15.8 0.0 0.042 14.0 0.0 1.8 3 0 0 3 3 3 0 Integrase core domain DUF4932 PF16286.5 EGC30682.1 - 0.014 14.7 0.1 0.02 14.2 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4932) Sina PF03145.16 EGC30682.1 - 0.024 14.6 0.0 0.029 14.3 0.0 1.2 1 0 0 1 1 1 0 Seven in absentia protein family PARM PF17061.5 EGC30683.1 - 0.12 12.5 32.2 0.2 11.7 32.2 1.3 1 0 0 1 1 1 0 PARM PulG PF11773.8 EGC30684.1 - 0.033 14.0 0.5 0.038 13.8 0.5 1.2 1 0 0 1 1 1 0 Type II secretory pathway pseudopilin CTU2 PF10288.9 EGC30685.1 - 0.03 14.5 0.1 0.043 14.1 0.1 1.2 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 Vps26 PF03643.15 EGC30686.1 - 9.1e-44 149.5 1.4 1.2e-43 149.1 1.4 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.29 EGC30686.1 - 2e-07 31.2 0.6 9.4e-07 29.0 0.1 2.3 3 1 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Act-Frag_cataly PF09192.10 EGC30687.1 - 2.1e-63 214.4 13.9 2.1e-63 214.4 13.9 1.5 2 0 0 2 2 2 1 Actin-fragmin kinase, catalytic TPR_2 PF07719.17 EGC30689.1 - 0.81 10.0 7.9 10 6.5 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RabGAP-TBC PF00566.18 EGC30690.1 - 2.5e-47 161.3 0.1 3.5e-47 160.9 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain p450 PF00067.22 EGC30691.1 - 7.4e-91 305.2 0.5 8.9e-91 304.9 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.6 EGC30692.1 - 1.6e-07 31.2 0.2 1.8e-07 31.0 0.2 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease LisH_TPL PF17814.1 EGC30692.1 - 0.011 15.3 0.1 0.019 14.6 0.1 1.3 1 0 0 1 1 1 0 LisH-like dimerisation domain zf-B_box PF00643.24 EGC30693.1 - 1.2e-05 25.4 4.8 1.2e-05 25.4 4.8 2.0 2 0 0 2 2 2 1 B-box zinc finger Eapp_C PF10238.9 EGC30693.1 - 0.00077 19.6 3.2 0.001 19.2 3.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein Uteroglobin PF01099.17 EGC30693.1 - 0.052 13.9 1.6 0.075 13.4 1.4 1.4 1 1 0 1 1 1 0 Uteroglobin family TBCA PF02970.16 EGC30693.1 - 0.082 13.3 1.2 0.13 12.6 1.2 1.3 1 0 0 1 1 1 0 Tubulin binding cofactor A NEMP PF10225.9 EGC30693.1 - 0.11 12.2 0.1 0.13 11.9 0.1 1.1 1 0 0 1 1 1 0 NEMP family PRP1_N PF06424.12 EGC30693.1 - 0.29 11.5 1.4 0.39 11.1 1.2 1.4 1 1 0 1 1 1 0 PRP1 splicing factor, N-terminal zf-UBR PF02207.20 EGC30693.1 - 1.6 8.9 8.9 0.88 9.8 4.8 2.4 2 1 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) FNIP PF05725.12 EGC30694.1 - 3.3e-07 30.4 4.7 1.4e-05 25.2 0.4 7.0 7 1 0 7 7 7 3 FNIP Repeat zf-B_box PF00643.24 EGC30694.1 - 1.4e-06 28.3 4.1 1.4e-06 28.3 4.1 1.9 2 0 0 2 2 2 1 B-box zinc finger NTP_transf_2 PF01909.23 EGC30694.1 - 0.072 13.4 0.3 0.91 9.9 0.0 3.2 2 1 0 2 2 2 0 Nucleotidyltransferase domain TT1725 PF18324.1 EGC30694.1 - 0.22 11.6 1.8 1.7 8.7 0.3 2.6 2 0 0 2 2 2 0 Hypothetical protein TT1725 zf-UBR PF02207.20 EGC30694.1 - 0.26 11.5 3.1 0.66 10.2 3.1 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) YchF-GTPase_C PF06071.13 EGC30695.1 - 1.5e-40 137.3 0.7 1.5e-40 137.3 0.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.23 EGC30695.1 - 3.8e-20 72.1 0.0 8.7e-20 70.9 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC30695.1 - 2.8e-06 26.9 0.0 9.1e-06 25.3 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B MeaB PF03308.16 EGC30695.1 - 0.11 11.5 0.0 0.2 10.6 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB RsgA_N PF16745.5 EGC30695.1 - 0.13 12.0 0.0 0.24 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA N-terminal domain DUF4134 PF13572.6 EGC30696.1 - 0.18 12.1 2.6 4.1 7.8 2.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4134) DUF4190 PF13828.6 EGC30696.1 - 3 7.7 5.6 6.7 6.6 3.3 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) RWD PF05773.22 EGC30697.1 - 3.7e-11 43.3 0.3 9e-11 42.1 0.1 1.8 2 0 0 2 2 2 1 RWD domain DFRP_C PF16543.5 EGC30697.1 - 1.5e-08 35.0 3.3 1.5e-08 35.0 3.3 1.7 2 0 0 2 2 2 1 DRG Family Regulatory Proteins, Tma46 DUF4502 PF14950.6 EGC30697.1 - 0.11 11.9 4.2 0.16 11.4 4.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4502) GST_C_3 PF14497.6 EGC30698.1 - 1.4e-13 50.9 1.1 2.5e-13 50.0 0.7 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC30698.1 - 2.1e-12 47.2 0.0 1.6e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC30698.1 - 4.1e-09 36.5 0.4 1.5e-08 34.7 0.4 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC30698.1 - 1.9e-08 34.6 0.0 4.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC30698.1 - 0.0003 20.8 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC30698.1 - 0.0099 16.6 0.0 0.025 15.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGC30698.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC30699.1 - 1.4e-13 50.9 1.1 2.5e-13 50.0 0.7 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC30699.1 - 2.1e-12 47.2 0.0 1.6e-11 44.4 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC30699.1 - 4.1e-09 36.5 0.4 1.5e-08 34.7 0.4 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC30699.1 - 1.9e-08 34.6 0.0 4.2e-08 33.5 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC30699.1 - 0.0003 20.8 0.0 0.0005 20.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC30699.1 - 0.0099 16.6 0.0 0.025 15.3 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGC30699.1 - 0.1 12.9 0.0 0.22 11.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain DUF3430 PF11912.8 EGC30701.1 - 1.5e-14 54.5 30.8 1.9e-14 54.2 30.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3430 PF11912.8 EGC30702.1 - 1.3e-15 58.1 33.1 1.6e-15 57.7 33.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC30702.1 - 0.22 11.8 8.4 3.7 7.8 0.9 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) AKNA PF12443.8 EGC30703.1 - 0.037 14.7 1.1 1.5 9.5 0.0 2.4 2 0 0 2 2 2 0 AT-hook-containing transcription factor GerA PF03323.13 EGC30703.1 - 0.52 8.7 2.7 0.96 7.8 2.7 1.5 1 0 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein SH3_1 PF00018.28 EGC30704.1 - 4.1e-14 51.9 0.2 8e-14 51.0 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC30704.1 - 4.7e-13 48.8 0.3 9e-13 47.9 0.3 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC30704.1 - 3.1e-11 42.8 0.0 5.7e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain AAA_23 PF13476.6 EGC30704.1 - 0.01 16.4 4.3 0.01 16.4 4.3 2.4 1 1 1 2 2 2 0 AAA domain DUF3287 PF11690.8 EGC30704.1 - 0.46 10.2 3.8 4.3 7.1 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3287) SR-25 PF10500.9 EGC30704.1 - 3.5 7.2 19.2 1 8.9 9.1 2.3 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein ICMT PF04140.14 EGC30705.1 - 1.3e-27 96.1 0.1 2.6e-27 95.1 0.1 1.5 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.13 EGC30705.1 - 4.2e-10 40.0 1.5 4.2e-10 40.0 1.5 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase NnrU PF07298.11 EGC30705.1 - 0.00028 20.5 1.5 0.00044 19.8 1.5 1.3 1 0 0 1 1 1 1 NnrU protein DUF1295 PF06966.12 EGC30705.1 - 0.0059 16.1 3.6 0.0081 15.7 3.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DAP_epimerase PF01678.19 EGC30707.1 - 1.3e-32 112.5 0.5 6.8e-15 55.3 0.0 2.6 2 1 0 2 2 2 2 Diaminopimelate epimerase PAS_10 PF13596.6 EGC30707.1 - 0.022 15.4 0.0 0.045 14.4 0.0 1.4 1 0 0 1 1 1 0 PAS domain APP_N PF02177.16 EGC30708.1 - 0.085 13.2 0.7 0.16 12.3 0.3 1.5 1 1 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding MS_channel PF00924.18 EGC30708.1 - 4.3 6.8 11.8 14 5.1 6.2 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel CDC45 PF02724.14 EGC30709.1 - 0.0014 17.1 22.7 0.0017 16.7 22.7 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EGC30709.1 - 0.0026 17.9 23.7 0.0039 17.4 23.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein DDHD PF02862.17 EGC30709.1 - 0.014 15.6 7.7 0.025 14.7 7.7 1.5 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.17 EGC30709.1 - 0.25 10.1 16.3 0.45 9.2 16.3 1.4 1 0 0 1 1 1 0 Presenilin HbrB PF08539.11 EGC30709.1 - 0.5 10.4 6.2 0.98 9.4 5.9 1.8 1 1 0 1 1 1 0 HbrB-like DUF2052 PF09747.9 EGC30709.1 - 0.52 10.4 20.1 0.91 9.6 20.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Ndc1_Nup PF09531.10 EGC30709.1 - 0.61 8.7 2.5 0.71 8.5 2.5 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SLC12 PF03522.15 EGC30709.1 - 0.76 8.7 19.4 1.2 8.0 19.4 1.3 1 0 0 1 1 1 0 Solute carrier family 12 RR_TM4-6 PF06459.12 EGC30709.1 - 0.82 9.4 21.7 1.6 8.5 21.7 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 NPR3 PF03666.13 EGC30709.1 - 1.7 7.3 19.7 2.9 6.6 19.7 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 TEX19 PF15553.6 EGC30709.1 - 1.8 8.5 5.5 4.3 7.3 5.5 1.7 1 1 0 1 1 1 0 Testis-expressed protein 19 DUF4419 PF14388.6 EGC30711.1 - 2.2e-90 303.2 0.1 2.2e-90 303.2 0.1 1.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) S-l_SbsC_C PF18316.1 EGC30711.1 - 2.1 8.9 5.5 0.45 11.0 1.0 2.2 2 0 0 2 2 2 0 S-layer protein SbsC C-terminal domain Y1_Tnp PF01797.16 EGC30712.1 - 0.13 12.4 0.8 0.41 10.7 0.1 2.1 2 0 0 2 2 2 0 Transposase IS200 like E1-E2_ATPase PF00122.20 EGC30713.1 - 1.5e-49 168.0 3.7 4e-49 166.6 3.7 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGC30713.1 - 1.1e-39 136.9 0.0 2e-39 136.1 0.0 1.4 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGC30713.1 - 1.6e-28 98.9 0.5 1.3e-11 44.8 0.2 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGC30713.1 - 1.9e-05 24.5 0.1 0.024 14.4 0.1 2.9 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC30713.1 - 0.0014 19.0 0.3 0.011 16.1 0.0 2.4 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Cypo_polyhedrin PF05865.11 EGC30713.1 - 0.068 12.5 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Cypovirus polyhedrin protein Pox_A14 PF05767.12 EGC30713.1 - 0.21 11.7 1.4 0.67 10.1 0.1 2.6 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 p450 PF00067.22 EGC30714.1 - 3.7e-95 319.4 0.0 4.1e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PP2C PF00481.21 EGC30715.1 - 5.2e-40 137.7 0.0 9.1e-40 136.9 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C GDP_Man_Dehyd PF16363.5 EGC30716.1 - 3.9e-28 98.8 1.4 4.7e-28 98.6 0.3 1.6 1 1 1 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC30716.1 - 6.1e-24 84.8 0.1 1e-23 84.1 0.1 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LRR_8 PF13855.6 EGC30716.1 - 3.4e-19 68.4 31.3 1.3e-12 47.3 1.6 6.4 1 1 5 6 6 6 4 Leucine rich repeat Polysacc_synt_2 PF02719.15 EGC30716.1 - 1e-14 54.4 0.0 2.5e-14 53.1 0.0 1.6 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein LRR_4 PF12799.7 EGC30716.1 - 6e-12 45.6 53.0 1.7e-05 25.1 1.0 7.6 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) 3Beta_HSD PF01073.19 EGC30716.1 - 1.6e-09 37.2 3.5 3.1e-09 36.2 3.5 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGC30716.1 - 1.8e-08 33.9 0.0 3.1e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGC30716.1 - 1.7e-07 30.7 0.1 2.7e-07 30.0 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein LRR_1 PF00560.33 EGC30716.1 - 0.022 15.2 42.7 2.3 9.1 0.2 10.6 9 2 2 11 11 11 0 Leucine Rich Repeat LRR_6 PF13516.6 EGC30716.1 - 0.15 12.2 31.9 14 6.0 0.0 9.1 9 0 0 9 9 9 0 Leucine Rich repeat Pkinase_Tyr PF07714.17 EGC30717.1 - 6.4e-51 173.1 0.0 1.1e-50 172.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30717.1 - 3.7e-44 151.1 0.0 7.1e-44 150.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGC30717.1 - 1.9e-33 115.9 0.1 1.3e-23 83.8 0.0 2.5 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Roc PF08477.13 EGC30717.1 - 1.3e-20 73.8 0.4 1.3e-14 54.5 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 EGC30717.1 - 1.2e-18 66.6 30.2 3.7e-08 33.0 3.7 6.4 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGC30717.1 - 6.9e-18 64.5 34.4 7.3e-07 29.4 1.2 6.3 6 1 1 7 7 6 5 Leucine Rich repeats (2 copies) Ras PF00071.22 EGC30717.1 - 2.5e-11 43.4 6.4 6.1e-09 35.7 0.0 3.1 4 0 0 4 4 4 2 Ras family PH PF00169.29 EGC30717.1 - 8.4e-08 32.7 0.4 2.8e-07 31.0 0.4 2.0 1 0 0 1 1 1 1 PH domain LRR_1 PF00560.33 EGC30717.1 - 0.00059 20.0 27.1 0.42 11.4 0.3 9.3 7 1 1 8 8 8 2 Leucine Rich Repeat Arf PF00025.21 EGC30717.1 - 0.00093 18.7 0.1 0.52 9.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family LRR_6 PF13516.6 EGC30717.1 - 6.5 7.1 32.2 0.041 14.0 0.5 7.7 8 0 0 8 8 7 0 Leucine Rich repeat DUF3979 PF13141.6 EGC30718.1 - 0.03 14.6 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) DUF4509 PF14970.6 EGC30719.1 - 0.0015 18.5 1.3 0.0019 18.2 1.3 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4509) FlxA PF14282.6 EGC30719.1 - 0.033 14.2 6.3 0.033 14.2 6.3 1.8 2 0 0 2 2 2 0 FlxA-like protein DUF4763 PF15960.5 EGC30719.1 - 0.62 9.3 8.9 0.41 9.9 7.3 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) zf-LSD1 PF06943.12 EGC30720.1 - 0.13 12.1 1.5 3.2 7.7 0.0 2.2 2 0 0 2 2 2 0 LSD1 zinc finger zf-RING_2 PF13639.6 EGC30721.1 - 1.2e-07 31.9 12.9 2e-07 31.2 12.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC30721.1 - 2.9e-06 27.0 12.9 4.9e-06 26.3 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC30721.1 - 2.3e-05 24.1 10.0 3.5e-05 23.6 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30721.1 - 2.9e-05 23.8 14.1 5.4e-05 23.0 14.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC30721.1 - 0.00017 21.8 9.4 0.00034 20.8 9.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC30721.1 - 0.0046 17.0 10.5 0.01 15.8 10.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGC30721.1 - 0.0065 16.2 6.5 0.016 14.9 6.5 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGC30721.1 - 0.047 13.7 12.6 0.078 13.0 12.6 1.4 1 0 0 1 1 1 0 zinc-RING finger domain ArsP_1 PF03773.13 EGC30721.1 - 0.12 11.6 0.2 0.18 10.9 0.2 1.3 1 0 0 1 1 1 0 Predicted permease LapA_dom PF06305.11 EGC30721.1 - 0.14 12.0 0.3 0.14 12.0 0.3 2.2 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain 7tm_1 PF00001.21 EGC30721.1 - 0.17 11.2 3.0 5.9 6.1 2.1 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) zf-C3HC4_4 PF15227.6 EGC30721.1 - 0.19 11.9 12.4 0.52 10.5 12.4 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC30721.1 - 0.51 10.2 12.4 1.6 8.6 12.4 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGC30721.1 - 1.6 8.8 9.1 2.6 8.2 9.1 1.3 1 0 0 1 1 1 0 Double zinc ribbon TMEMspv1-c74-12 PF11044.8 EGC30721.1 - 4.4 7.4 12.8 0.063 13.3 4.5 2.1 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein U-box PF04564.15 EGC30721.1 - 6.8 6.9 6.3 11 6.2 0.0 3.2 3 1 0 3 3 3 0 U-box domain Ank_4 PF13637.6 EGC30722.1 - 4.8e-18 65.3 1.3 1.4e-12 47.9 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC30722.1 - 1.8e-16 60.0 1.6 4e-09 36.5 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC30722.1 - 1.7e-13 50.9 0.2 2.7e-13 50.3 0.2 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGC30722.1 - 5.5e-13 48.7 2.0 5.8e-06 26.5 0.4 2.4 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGC30722.1 - 3.1e-12 45.5 0.4 4.8e-05 23.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Phosphoprotein PF00922.17 EGC30722.1 - 0.84 9.2 5.7 1.2 8.7 5.7 1.2 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein FKBP_C PF00254.28 EGC30723.1 - 3.3e-21 75.4 0.0 4e-21 75.1 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dimer_Tnp_hAT PF05699.14 EGC30724.1 - 0.0049 16.6 0.1 0.0067 16.2 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-B_box PF00643.24 EGC30725.1 - 0.012 15.8 5.3 0.012 15.8 5.3 3.2 2 0 0 2 2 2 0 B-box zinc finger Zip PF02535.22 EGC30725.1 - 5.3 6.1 7.6 0.51 9.5 2.0 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Pox_MCEL PF03291.16 EGC30726.1 - 2e-30 106.1 5.8 3.1e-29 102.1 5.8 2.2 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.12 EGC30726.1 - 1.6e-06 28.8 0.8 0.0022 18.7 0.5 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30726.1 - 1.1e-05 26.0 0.0 0.24 12.1 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGC30726.1 - 1.9e-05 25.2 0.0 0.22 12.2 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGC30726.1 - 8e-05 22.5 0.1 0.00077 19.3 0.1 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC30726.1 - 0.037 13.8 0.6 0.41 10.4 0.6 2.1 1 1 0 1 1 1 0 Methyltransferase domain LRR_9 PF14580.6 EGC30727.1 - 1.6e-06 27.7 4.5 1e-05 25.2 4.5 2.4 1 1 0 1 1 1 1 Leucine-rich repeat JHD PF17811.1 EGC30727.1 - 0.012 16.2 0.2 0.053 14.1 0.2 2.2 1 0 0 1 1 1 0 Jumonji helical domain Snf7 PF03357.21 EGC30727.1 - 0.036 13.7 4.1 0.097 12.3 4.1 1.7 1 0 0 1 1 1 0 Snf7 DUF1771 PF08590.10 EGC30728.1 - 1e-10 41.8 9.2 1.8e-10 41.0 9.2 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGC30728.1 - 6.5e-10 39.2 0.0 1.7e-09 37.9 0.0 1.7 1 0 0 1 1 1 1 Smr domain GAS PF13851.6 EGC30728.1 - 0.85 8.9 16.1 1.2 8.4 15.0 1.8 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Atg14 PF10186.9 EGC30728.1 - 1.4 8.0 7.4 1.8 7.6 7.4 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Condensin2nSMC PF12422.8 EGC30729.1 - 5.3e-52 176.0 1.8 5.3e-52 176.0 1.8 4.2 4 1 0 4 4 4 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.22 EGC30729.1 - 6.6e-05 22.8 0.2 4.5 7.8 0.1 4.7 4 0 0 4 4 4 3 HEAT repeat Oxysterol_BP PF01237.18 EGC30730.1 - 1.7e-105 352.9 6.2 2.7e-105 352.3 6.2 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein DUF916 PF06030.12 EGC30730.1 - 0.01 15.9 1.4 0.031 14.3 1.4 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Med2 PF11214.8 EGC30730.1 - 0.076 13.2 2.4 0.22 11.7 2.4 1.9 1 0 0 1 1 1 0 Mediator complex subunit 2 OTU PF02338.19 EGC30731.1 - 9.2e-13 48.8 0.0 2.4e-12 47.5 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease SARAF PF06682.12 EGC30731.1 - 0.0029 17.3 3.4 0.0038 16.9 3.4 1.2 1 0 0 1 1 1 1 SOCE-associated regulatory factor of calcium homoeostasis PPP4R2 PF09184.11 EGC30731.1 - 0.19 11.3 4.4 0.25 10.9 4.4 1.1 1 0 0 1 1 1 0 PPP4R2 CDK2AP PF09806.9 EGC30731.1 - 0.37 10.8 12.8 0.7 9.9 12.8 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 EGC30731.1 - 0.64 10.0 19.8 1 9.3 19.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ctr PF04145.15 EGC30731.1 - 4.1 8.0 5.2 10 6.7 5.2 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DUF4834 PF16118.5 EGC30731.1 - 6.7 7.7 15.5 1.8e+02 3.1 15.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Adeno_E1B_55K PF01696.17 EGC30733.1 - 0.68 8.6 3.4 0.82 8.3 3.4 1.0 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen zinc_ribbon_2 PF13240.6 EGC30734.1 - 0.00015 21.4 7.5 0.00028 20.5 7.5 1.5 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGC30734.1 - 0.0052 16.8 2.8 0.013 15.6 2.8 1.7 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.6 EGC30734.1 - 0.052 13.0 6.3 0.12 11.8 6.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain DUF228 PF02989.14 EGC30734.1 - 0.42 10.4 1.9 0.57 10.0 1.9 1.1 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Nudix_N_2 PF14803.6 EGC30734.1 - 0.47 10.4 10.4 0.91 9.5 2.4 2.4 2 0 0 2 2 2 0 Nudix N-terminal DUF3292 PF11696.8 EGC30734.1 - 1.4 7.2 5.9 1.8 6.9 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) YqzE PF14038.6 EGC30734.1 - 2.6 8.1 6.6 5.2 7.2 6.6 1.5 1 0 0 1 1 1 0 YqzE-like protein ICAT PF06384.11 EGC30735.1 - 1.7e-30 105.1 0.6 1.7e-30 105.1 0.6 2.3 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT GvpG PF05120.12 EGC30735.1 - 0.00044 20.2 13.8 0.0088 16.0 0.1 2.9 2 2 1 3 3 3 2 Gas vesicle protein G CAMP_factor PF07373.11 EGC30735.1 - 0.0046 16.6 1.2 0.0085 15.7 1.2 1.4 1 0 0 1 1 1 1 CAMP factor (Cfa) PCAF_N PF06466.11 EGC30735.1 - 0.024 14.2 1.0 0.041 13.5 1.0 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain DUF3313 PF11769.8 EGC30735.1 - 0.03 14.1 0.1 0.059 13.2 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3313) GATase1_like PF07090.11 EGC30735.1 - 0.065 12.7 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Putative glutamine amidotransferase dCache_2 PF08269.11 EGC30735.1 - 2.5 7.2 9.2 3.6 6.7 2.3 2.5 2 1 1 3 3 3 0 Cache domain RSS_P20 PF11757.8 EGC30735.1 - 2.9 8.4 8.1 12 6.5 2.7 2.9 2 1 0 2 2 2 0 Suppressor of RNA silencing P21-like N-terminal domain Comm PF15957.5 EGC30736.1 - 0.075 13.4 3.7 0.079 13.3 0.0 2.6 2 1 0 2 2 2 0 Commissureless COX17 PF05051.13 EGC30737.1 - 8.1e-21 74.1 8.4 9.7e-21 73.9 8.4 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) SMK-1 PF04802.15 EGC30738.1 - 9.6e-22 77.7 15.5 2.6e-10 40.5 1.7 4.7 2 1 2 4 4 4 3 Component of IIS longevity pathway SMK-1 FUN14 PF04930.15 EGC30739.1 - 3.8e-24 84.9 1.8 3.8e-24 84.9 1.8 2.1 2 0 0 2 2 2 1 FUN14 family Shisa PF13908.6 EGC30739.1 - 0.065 13.5 1.8 0.12 12.6 0.1 2.0 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Deltameth_res PF16020.5 EGC30739.1 - 0.2 11.5 2.4 1.3 8.9 0.0 3.0 3 0 0 3 3 3 0 Deltamethrin resistance Claudin_2 PF13903.6 EGC30739.1 - 0.55 9.9 3.1 2.4 7.9 3.1 2.1 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Ashwin PF15323.6 EGC30739.1 - 1.5 8.8 5.4 2.2 8.2 5.4 1.2 1 0 0 1 1 1 0 Developmental protein DUF3899 PF13038.6 EGC30739.1 - 2.9 8.4 9.2 1.8 9.2 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) PhoLip_ATPase_C PF16212.5 EGC30740.1 - 5.3e-73 245.9 28.9 5.3e-73 245.9 28.9 3.1 4 0 0 4 4 4 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC30740.1 - 7.6e-18 64.0 2.3 5.7e-17 61.2 2.3 2.6 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGC30740.1 - 1.7e-12 47.2 0.1 5.7e-11 42.4 0.0 2.8 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC30740.1 - 1e-08 35.7 0.4 0.00052 20.4 0.2 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGC30740.1 - 9.2e-07 28.6 0.0 5.1e-06 26.1 0.0 2.3 1 0 0 1 1 1 1 E1-E2 ATPase SelK_SelG PF10961.8 EGC30740.1 - 0.3 11.7 1.3 2.3 8.9 1.3 2.6 1 0 0 1 1 1 0 Selenoprotein SelK_SelG Lustrin_cystein PF14625.6 EGC30741.1 - 2.8e-05 24.4 19.6 0.041 14.3 2.3 3.5 1 1 2 3 3 3 3 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.12 EGC30741.1 - 0.0033 17.9 14.8 0.14 12.7 7.2 2.6 1 1 1 2 2 2 2 Dickkopf N-terminal cysteine-rich region Defensin_int PF17858.1 EGC30741.1 - 0.029 14.3 2.4 0.029 14.3 2.4 2.6 1 1 1 2 2 2 0 Platypus intermediate defensin-like peptide Granulin PF00396.18 EGC30741.1 - 0.097 13.0 16.8 3.8 7.9 1.5 3.6 1 1 2 3 3 3 0 Granulin EB PF01683.18 EGC30741.1 - 0.94 9.8 17.0 0.049 13.9 8.4 2.4 2 0 0 2 2 2 0 EB module Peptidase_S9 PF00326.21 EGC30742.1 - 2.5e-05 23.9 0.0 5.5e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC30742.1 - 0.007 15.7 0.7 4.9 6.3 0.1 2.8 2 1 0 3 3 3 2 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGC30742.1 - 0.076 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_1 PF00561.20 EGC30742.1 - 0.079 12.6 0.3 0.42 10.2 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC30742.1 - 0.11 13.1 0.0 0.19 12.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family HSA PF07529.13 EGC30743.1 - 0.13 12.6 12.7 1 9.8 0.4 3.2 1 1 1 3 3 3 0 HSA AKNA PF12443.8 EGC30743.1 - 0.35 11.5 6.5 4.3 8.0 0.2 2.6 1 1 0 2 2 2 0 AT-hook-containing transcription factor SKA2 PF16740.5 EGC30743.1 - 0.7 9.7 14.2 2.3 8.0 2.7 2.8 2 1 1 3 3 3 0 Spindle and kinetochore-associated protein 2 DUF1640 PF07798.11 EGC30743.1 - 2.7 8.0 17.8 1.9 8.5 2.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1640) Oxidored_FMN PF00724.20 EGC30744.1 - 1.6e-73 247.9 0.0 1.9e-73 247.7 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGC30744.1 - 0.0051 15.9 0.0 0.008 15.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Corona_NS2 PF04753.12 EGC30744.1 - 0.19 12.3 0.0 0.73 10.4 0.0 1.9 1 0 0 1 1 1 0 Coronavirus non-structural protein NS2 Erf4 PF10256.9 EGC30745.1 - 2.7e-06 27.5 0.6 3.1e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4271 PF14093.6 EGC30745.1 - 0.007 16.3 7.2 0.016 15.2 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF4271) Oxidored_q3 PF00499.20 EGC30745.1 - 0.017 14.8 0.1 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Glucos_trans_II PF14264.6 EGC30745.1 - 0.024 14.0 0.0 0.035 13.5 0.0 1.2 1 0 0 1 1 1 0 Glucosyl transferase GtrII PrgI PF12666.7 EGC30745.1 - 0.055 14.2 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 PrgI family protein DUF4131 PF13567.6 EGC30745.1 - 0.059 13.0 0.0 0.088 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mtp PF03821.16 EGC30745.1 - 0.06 12.9 0.2 0.081 12.5 0.2 1.1 1 0 0 1 1 1 0 Golgi 4-transmembrane spanning transporter DUF3899 PF13038.6 EGC30745.1 - 2.5 8.6 7.5 17 6.0 2.3 3.2 2 1 0 2 2 2 0 Domain of unknown function (DUF3899) Orf78 PF06024.12 EGC30746.1 - 0.013 15.8 0.2 0.021 15.1 0.2 1.3 1 0 0 1 1 1 0 Orf78 (ac78) TMEM154 PF15102.6 EGC30746.1 - 0.03 14.2 3.3 0.052 13.5 3.3 1.3 1 0 0 1 1 1 0 TMEM154 protein family OTU PF02338.19 EGC30747.1 - 1.1e-08 35.6 2.2 3.9e-05 24.2 0.2 2.1 1 1 1 2 2 2 2 OTU-like cysteine protease AFP PF02420.15 EGC30749.1 - 0.38 11.2 5.4 2.1 9.0 0.8 5.1 3 0 0 3 3 3 0 Insect antifreeze protein repeat FERM_N PF09379.10 EGC30750.1 - 3.3e-05 23.7 0.0 0.056 13.4 0.0 2.7 2 0 0 2 2 2 2 FERM N-terminal domain TUG-UBL1 PF11470.8 EGC30750.1 - 0.00067 19.8 0.1 0.019 15.2 0.0 2.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain TPR_MLP1_2 PF07926.12 EGC30750.1 - 0.00097 19.2 27.3 0.00097 19.2 27.3 4.4 2 2 2 4 4 4 2 TPR/MLP1/MLP2-like protein Fez1 PF06818.15 EGC30750.1 - 0.013 16.0 17.7 0.013 16.0 17.7 3.6 1 1 1 2 2 2 0 Fez1 DDE_Tnp_4 PF13359.6 EGC30751.1 - 3.5e-07 30.0 0.0 6.9e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PHM7_ext PF12621.8 EGC30752.1 - 2.8 8.2 5.9 3.5 7.9 0.0 3.4 3 0 0 3 3 3 0 Extracellular tail, of 10TM putative phosphate transporter DUF3038 PF11237.8 EGC30752.1 - 7.4 6.6 6.6 1.3 9.0 2.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3038) DUF2207 PF09972.9 EGC30754.1 - 0.00037 19.4 5.1 0.00052 18.9 5.1 1.2 1 1 0 1 1 1 1 Predicted membrane protein (DUF2207) FTA4 PF13093.6 EGC30754.1 - 0.018 14.9 0.9 0.032 14.1 0.9 1.3 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 PARP_reg PF02877.14 EGC30754.1 - 0.056 13.5 7.9 0.6 10.2 3.7 2.7 2 1 1 3 3 3 0 Poly(ADP-ribose) polymerase, regulatory domain ING PF12998.7 EGC30754.1 - 0.67 10.6 13.6 0.22 12.1 9.6 2.2 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DASH_Duo1 PF08651.10 EGC30754.1 - 1.3 8.8 10.1 5 7.0 0.2 3.6 2 1 2 4 4 4 0 DASH complex subunit Duo1 ApoL PF05461.11 EGC30755.1 - 0.0058 16.0 1.7 0.014 14.7 1.7 1.6 1 0 0 1 1 1 1 Apolipoprotein L DUF726 PF05277.12 EGC30755.1 - 0.0081 15.1 0.8 0.0081 15.1 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF726) IncD PF17628.2 EGC30755.1 - 0.043 13.6 0.7 0.078 12.8 0.7 1.4 1 0 0 1 1 1 0 Inclusion membrane protein D DUF1090 PF06476.12 EGC30755.1 - 0.095 12.8 0.2 0.095 12.8 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF1090) Phage_holin_3_6 PF07332.11 EGC30755.1 - 0.21 11.7 1.7 0.33 11.0 1.7 1.3 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III DUF3040 PF11239.8 EGC30755.1 - 3.8 7.9 4.9 7.8 6.9 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) FNIP PF05725.12 EGC30756.1 - 5.5e-09 36.1 31.7 1.5e-05 25.1 1.7 6.9 3 2 3 6 6 6 5 FNIP Repeat zf-TRAF PF02176.18 EGC30757.1 - 5.4e-17 62.2 18.4 1.7e-11 44.7 7.2 4.1 2 1 2 4 4 4 2 TRAF-type zinc finger MATH PF00917.26 EGC30757.1 - 1.9e-07 31.2 1.9 6.5e-07 29.5 1.9 2.0 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.6 EGC30757.1 - 4.9e-06 26.3 11.3 4.9e-06 26.3 11.3 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30757.1 - 0.0015 18.3 13.6 0.0015 18.3 13.6 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC30757.1 - 0.0037 17.2 0.8 0.0037 17.2 0.8 4.0 2 1 2 4 4 4 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC30757.1 - 0.023 15.1 10.3 0.023 15.1 10.3 3.7 1 1 2 3 3 3 0 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC30757.1 - 0.03 14.6 13.2 0.03 14.6 13.2 3.8 3 1 0 3 3 3 0 Ring finger domain CENP-H PF05837.12 EGC30757.1 - 0.06 13.8 0.3 0.15 12.5 0.3 1.6 1 0 0 1 1 1 0 Centromere protein H (CENP-H) MCC-bdg_PDZ PF10506.9 EGC30757.1 - 0.73 9.9 3.7 0.83 9.7 1.5 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.21 EGC30757.1 - 3.4 7.8 7.4 3.6 7.8 3.3 3.1 2 1 1 3 3 3 0 bZIP transcription factor DDRGK PF09756.9 EGC30758.1 - 1.7e-53 181.0 31.7 1.7e-53 181.0 31.7 2.1 2 0 0 2 2 2 1 DDRGK domain DUF4604 PF15377.6 EGC30758.1 - 0.0075 16.7 23.4 0.013 16.0 23.4 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4604) ABC2_membrane_3 PF12698.7 EGC30758.1 - 0.05 12.7 0.1 0.096 11.8 0.1 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2149 PF09919.9 EGC30758.1 - 0.09 13.0 0.5 0.09 13.0 0.5 3.0 1 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Dapper PF15268.6 EGC30758.1 - 0.36 9.6 20.7 0.48 9.2 20.7 1.1 1 0 0 1 1 1 0 Dapper Elongin_A PF06881.11 EGC30759.1 - 3.9e-20 72.3 0.1 1.2e-19 70.8 0.1 1.9 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A CAP_GLY PF01302.25 EGC30759.1 - 8.6e-20 70.5 2.0 1.5e-19 69.8 2.0 1.4 1 0 0 1 1 1 1 CAP-Gly domain LRR_8 PF13855.6 EGC30759.1 - 3e-14 52.5 42.6 9.3e-08 31.7 10.2 4.3 2 1 3 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGC30759.1 - 7.7e-13 48.4 35.4 1.7e-06 28.2 3.3 4.9 3 2 3 6 6 6 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC30759.1 - 5.2e-05 22.8 14.9 0.00091 18.8 5.0 3.1 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EGC30759.1 - 0.00051 20.2 20.1 4.3 8.3 0.4 7.1 6 0 0 6 6 6 3 Leucine Rich Repeat LRR_6 PF13516.6 EGC30759.1 - 0.026 14.6 24.9 3.4 8.0 0.8 7.2 7 1 0 7 7 7 0 Leucine Rich repeat AIRS_C PF02769.22 EGC30759.1 - 0.041 14.0 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain Alpha_E2_glycop PF00943.19 EGC30761.1 - 0.017 13.9 0.1 0.024 13.4 0.1 1.1 1 0 0 1 1 1 0 Alphavirus E2 glycoprotein RCR PF12273.8 EGC30761.1 - 0.049 14.3 6.0 0.12 13.0 0.1 2.9 2 1 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red Cadherin_C_2 PF16492.5 EGC30761.1 - 1.3 9.8 5.7 14 6.5 0.9 2.9 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal Acetyltransf_1 PF00583.25 EGC30762.1 - 1.2e-11 44.8 0.1 2e-11 44.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC30762.1 - 2.3e-07 30.8 0.3 3.6e-07 30.2 0.3 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC30762.1 - 3e-07 30.7 0.4 5.1e-07 30.0 0.4 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC30762.1 - 1.7e-06 27.9 0.0 2.7e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGC30762.1 - 3.2e-05 24.1 0.9 4.9e-05 23.5 0.9 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC30762.1 - 0.0034 18.1 0.0 0.0063 17.2 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC30762.1 - 0.0042 16.6 0.9 0.0061 16.1 0.9 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_8 PF13523.6 EGC30762.1 - 0.0043 16.8 0.0 0.0059 16.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Baculo_E56 PF04639.12 EGC30762.1 - 0.0076 15.6 2.1 0.008 15.5 1.1 1.5 2 0 0 2 2 2 1 Baculoviral E56 protein, specific to ODV envelope PBP1_TM PF14812.6 EGC30762.1 - 0.082 13.3 0.1 3 8.3 0.0 2.2 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FbpA PF05833.11 EGC30763.1 - 4.2e-38 131.3 20.5 4.2e-38 131.3 20.5 4.1 4 1 0 4 4 4 1 Fibronectin-binding protein A N-terminus (FbpA) NFACT-R_1 PF05670.13 EGC30763.1 - 7.2e-34 116.7 2.2 1.7e-33 115.5 0.1 2.8 2 0 0 2 2 2 1 NFACT protein RNA binding domain NFACT-C PF11923.8 EGC30763.1 - 7.9e-25 86.8 0.0 7.9e-25 86.8 0.0 5.1 4 1 1 5 5 5 1 NFACT protein C-terminal domain LRR_8 PF13855.6 EGC30764.1 - 3.4e-28 97.2 36.1 1.7e-08 34.1 6.6 6.3 2 2 2 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EGC30764.1 - 9.9e-26 89.4 43.4 2.8e-05 24.4 4.4 8.0 3 2 5 9 9 9 8 Leucine Rich repeats (2 copies) Filamin PF00630.19 EGC30764.1 - 1.3e-14 54.9 0.1 2.3e-14 54.1 0.1 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_1 PF00560.33 EGC30764.1 - 3.3e-11 42.1 32.1 1.6 9.6 2.0 11.8 9 3 1 10 10 10 5 Leucine Rich Repeat LRR_9 PF14580.6 EGC30764.1 - 5.8e-09 35.7 18.9 0.0012 18.4 0.6 5.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_6 PF13516.6 EGC30764.1 - 0.0091 16.0 37.5 8.3 6.7 0.1 10.5 11 0 0 11 11 11 3 Leucine Rich repeat Ank_2 PF12796.7 EGC30765.1 - 6.4e-17 61.9 5.8 0.003 18.1 0.0 7.0 4 1 4 8 8 8 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC30765.1 - 9.5e-11 42.0 0.8 0.13 12.9 0.0 7.3 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC30765.1 - 2.4e-06 27.4 0.2 3.6 8.4 0.0 8.3 10 0 0 10 10 10 1 Ankyrin repeat Ank_5 PF13857.6 EGC30765.1 - 0.00031 21.0 0.0 30 5.1 0.0 6.6 5 2 2 7 7 7 1 Ankyrin repeats (many copies) DUF624 PF04854.14 EGC30765.1 - 0.036 14.2 4.6 1.4 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF624 EF-hand_8 PF13833.6 EGC30766.1 - 8.8e-07 28.7 1.3 5.9e-05 22.8 0.8 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.32 EGC30766.1 - 0.0001 21.6 1.9 0.055 13.0 0.2 3.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGC30766.1 - 0.00049 20.5 0.9 0.0029 18.0 0.4 2.7 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC30766.1 - 0.00062 19.5 3.6 0.12 12.3 0.2 3.8 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.6 EGC30766.1 - 0.0068 15.9 0.1 0.028 13.9 0.1 2.1 1 0 0 1 1 1 1 EF hand UBA PF00627.31 EGC30766.1 - 0.062 13.2 0.0 0.15 12.0 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain SPARC_Ca_bdg PF10591.9 EGC30766.1 - 0.063 13.6 4.6 0.18 12.1 0.0 3.3 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Mitofilin PF09731.9 EGC30766.1 - 0.065 12.1 21.8 0.12 11.2 21.8 1.4 1 0 0 1 1 1 0 Mitochondrial inner membrane protein SHNi-TPR PF10516.9 EGC30766.1 - 0.14 11.6 0.0 0.35 10.4 0.0 1.7 1 0 0 1 1 1 0 SHNi-TPR NARP1 PF12569.8 EGC30766.1 - 1.8 7.4 16.2 3.5 6.4 16.2 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-ribbon_3 PF13248.6 EGC30766.1 - 3.2 7.3 8.5 0.65 9.5 3.9 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TFIIA PF03153.13 EGC30766.1 - 3.9 7.4 36.0 0.32 11.0 19.0 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Kelch_1 PF01344.25 EGC30768.1 - 4.4e-05 23.0 0.0 4.4e-05 23.0 0.0 2.6 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.6 EGC30768.1 - 7.8e-05 22.6 1.7 0.001 19.0 0.0 2.7 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC30768.1 - 0.031 14.6 2.6 0.031 14.6 0.0 2.3 3 0 0 3 3 3 0 Kelch motif Solute_trans_a PF03619.16 EGC30769.1 - 1e-40 139.9 20.1 1.3e-40 139.6 20.1 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha Phage_pRha PF09669.10 EGC30769.1 - 0.11 13.1 0.6 9.2 6.9 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) FOG_N PF15888.5 EGC30769.1 - 0.11 12.8 1.1 0.21 11.9 1.1 1.5 1 0 0 1 1 1 0 Folded gastrulation N-terminus DUF656 PF04920.12 EGC30769.1 - 0.45 10.4 2.3 0.79 9.7 0.4 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF656) Methyltransf_2 PF00891.18 EGC30770.1 - 1.1e-32 113.1 0.0 9.4e-32 110.0 0.0 1.9 2 0 0 2 2 2 1 O-methyltransferase domain CheR PF01739.18 EGC30770.1 - 0.024 14.1 0.0 0.069 12.6 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain EF-hand_1 PF00036.32 EGC30771.1 - 6.7e-13 47.2 0.1 6e-07 28.6 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC30771.1 - 1.9e-12 46.9 0.1 7.1e-09 35.4 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGC30771.1 - 4.1e-10 40.0 0.0 4.7e-10 39.8 0.0 1.0 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC30771.1 - 1.5e-09 37.0 0.1 2.6e-07 30.0 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain EF-hand_9 PF14658.6 EGC30771.1 - 3e-06 27.5 0.0 3.6e-06 27.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.10 EGC30771.1 - 0.00035 20.6 0.4 0.0012 18.9 0.4 1.8 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.6 EGC30771.1 - 0.0061 16.0 0.0 0.013 15.0 0.0 1.6 1 0 0 1 1 1 1 EF hand DDE_Tnp_IS66_C PF13817.6 EGC30771.1 - 0.04 14.2 0.0 0.061 13.6 0.0 1.3 1 0 0 1 1 1 0 IS66 C-terminal element Pkinase PF00069.25 EGC30773.1 - 2e-47 161.8 0.1 2.5e-47 161.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30773.1 - 3.6e-31 108.4 0.0 4.1e-31 108.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1741 PF08427.10 EGC30773.1 - 0.0091 15.7 0.1 0.015 14.9 0.1 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1741) Kdo PF06293.14 EGC30773.1 - 0.016 14.6 0.0 0.03 13.7 0.0 1.5 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC30773.1 - 0.024 14.3 0.5 2.8 7.5 0.0 2.2 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Na_H_Exchanger PF00999.21 EGC30774.1 - 1.4e-60 205.1 40.0 1.8e-60 204.7 40.0 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hydrolase_6 PF13344.6 EGC30774.1 - 0.33 11.1 1.9 0.37 10.9 0.2 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase P21-Arc PF04062.14 EGC30776.1 - 1.7e-70 236.6 0.0 1.9e-70 236.4 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Cupin_8 PF13621.6 EGC30777.1 - 6.6e-70 235.7 0.5 8.5e-70 235.4 0.5 1.1 1 0 0 1 1 1 1 Cupin-like domain p450 PF00067.22 EGC30778.1 - 1.3e-93 314.3 0.0 1.5e-93 314.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 INT_SG_DDX_CT_C PF15300.6 EGC30778.1 - 0.032 14.0 0.4 0.23 11.3 0.4 2.4 1 1 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus ADK PF00406.22 EGC30779.1 - 3.2e-43 147.4 0.0 3.9e-43 147.1 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGC30779.1 - 2.9e-23 82.8 0.0 3.9e-23 82.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain ADK_lid PF05191.14 EGC30779.1 - 9.7e-16 57.5 0.0 1.6e-15 56.7 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.6 EGC30779.1 - 1.4e-08 35.0 0.0 3.8e-08 33.6 0.0 1.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC30779.1 - 3.2e-08 34.2 0.0 4.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGC30779.1 - 0.0016 18.1 0.1 0.11 12.2 0.0 2.3 2 0 0 2 2 2 1 Thymidylate kinase Zeta_toxin PF06414.12 EGC30779.1 - 0.011 15.1 0.0 0.069 12.4 0.0 1.9 1 1 0 1 1 1 0 Zeta toxin Csd3_N PF18059.1 EGC30779.1 - 0.013 16.0 0.1 22 5.6 0.0 3.1 3 0 0 3 3 3 0 Csd3 N-terminal AAA_28 PF13521.6 EGC30779.1 - 0.036 14.3 0.0 0.061 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.6 EGC30780.1 - 7.2e-10 39.0 9.7 1.6e-09 37.9 9.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC30780.1 - 3.4e-08 33.2 10.4 9.8e-08 31.7 10.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC30780.1 - 1.6e-07 31.1 6.6 3.4e-07 30.0 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30780.1 - 2.2e-07 30.6 8.7 4.7e-07 29.5 8.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC30780.1 - 6.1e-05 23.0 4.5 0.00017 21.5 4.5 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC30780.1 - 0.00018 21.7 9.2 0.00088 19.5 9.2 2.2 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC30780.1 - 0.00021 21.4 8.5 0.00073 19.6 8.5 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC30780.1 - 0.0087 15.8 9.5 0.018 14.9 9.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGC30780.1 - 0.02 14.9 8.5 0.055 13.4 8.5 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC30780.1 - 0.026 14.5 0.9 0.057 13.5 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGC30780.1 - 0.038 13.8 6.0 0.1 12.5 6.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.11 EGC30780.1 - 0.13 12.4 5.9 0.29 11.3 5.9 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 EGC30780.1 - 0.53 10.1 6.9 1.2 8.9 6.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 EGC30780.1 - 8.5 6.5 10.8 1.3 9.1 3.9 3.0 2 1 0 2 2 2 0 Double zinc ribbon AAA PF00004.29 EGC30782.1 - 3e-62 208.9 0.5 7.6e-45 152.6 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC30782.1 - 6.6e-11 42.9 0.2 0.0065 16.9 0.0 3.9 3 1 0 3 3 3 2 AAA ATPase domain RuvB_N PF05496.12 EGC30782.1 - 2.7e-08 33.7 0.0 0.00012 21.9 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC30782.1 - 8.2e-07 29.4 0.1 0.013 15.8 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA_18 PF13238.6 EGC30782.1 - 1.2e-06 29.1 4.3 0.022 15.3 0.0 4.4 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 EGC30782.1 - 1.5e-06 28.5 0.0 0.093 12.9 0.0 3.1 2 0 0 2 2 2 2 AAA domain TsaE PF02367.17 EGC30782.1 - 1.7e-06 28.1 0.0 0.052 13.5 0.0 2.7 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_5 PF07728.14 EGC30782.1 - 3.3e-06 27.1 0.1 0.042 13.9 0.1 3.6 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) IstB_IS21 PF01695.17 EGC30782.1 - 5.4e-06 26.3 0.1 0.0037 17.0 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_24 PF13479.6 EGC30782.1 - 5.7e-06 26.2 1.4 0.13 11.9 0.0 3.7 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGC30782.1 - 6e-06 26.6 0.0 0.0079 16.6 0.0 4.0 3 0 0 3 3 2 1 RNA helicase TIP49 PF06068.13 EGC30782.1 - 3.2e-05 23.3 2.8 0.012 14.8 0.0 3.0 3 0 0 3 3 3 2 TIP49 P-loop domain NB-ARC PF00931.22 EGC30782.1 - 4.5e-05 22.8 0.2 0.057 12.6 0.0 3.0 2 0 0 2 2 2 2 NB-ARC domain AAA_2 PF07724.14 EGC30782.1 - 7.9e-05 22.8 0.0 0.082 13.0 0.0 3.5 2 2 0 2 2 2 1 AAA domain (Cdc48 subfamily) Cytidylate_kin PF02224.18 EGC30782.1 - 8.6e-05 22.4 1.5 3.5 7.3 0.0 3.7 3 1 0 3 3 3 1 Cytidylate kinase AAA_14 PF13173.6 EGC30782.1 - 0.00018 21.6 11.8 0.07 13.2 0.0 4.9 4 1 0 4 4 3 2 AAA domain Mg_chelatase PF01078.21 EGC30782.1 - 0.00048 19.6 0.1 0.025 13.9 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGC30782.1 - 0.00061 19.3 0.0 0.15 11.6 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF815 PF05673.13 EGC30782.1 - 0.00067 18.9 0.0 0.29 10.3 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 EGC30782.1 - 0.0017 18.3 5.0 0.82 9.6 0.0 4.2 4 1 1 5 5 4 2 NACHT domain NTPase_1 PF03266.15 EGC30782.1 - 0.0021 18.0 0.6 1.5 8.7 0.0 3.1 3 0 0 3 3 2 1 NTPase AAA_lid_3 PF17862.1 EGC30782.1 - 0.0022 17.8 0.0 0.056 13.3 0.0 2.6 2 0 0 2 2 2 1 AAA+ lid domain ATPase PF06745.13 EGC30782.1 - 0.0025 17.2 4.3 0.034 13.5 0.0 2.8 2 0 0 2 2 2 1 KaiC AAA_28 PF13521.6 EGC30782.1 - 0.0028 17.9 0.0 0.18 12.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGC30782.1 - 0.003 18.0 0.9 1.3 9.5 0.0 3.6 3 1 0 3 3 3 1 AAA domain Sigma54_activat PF00158.26 EGC30782.1 - 0.004 16.9 0.0 0.9 9.2 0.0 3.0 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.6 EGC30782.1 - 0.0066 16.0 1.0 0.11 12.1 0.1 2.9 2 1 1 3 3 3 1 AAA domain AAA_3 PF07726.11 EGC30782.1 - 0.037 13.9 0.0 1.1 9.2 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGC30782.1 - 0.04 14.2 1.5 4.4 7.6 0.0 3.1 3 1 0 3 3 2 0 AAA domain Vps4_C PF09336.10 EGC30782.1 - 0.054 13.5 0.1 0.23 11.5 0.1 2.1 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain AAA_29 PF13555.6 EGC30782.1 - 0.058 13.2 3.4 2.8 7.8 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGC30782.1 - 0.058 12.4 0.2 4.5 6.3 0.1 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein SKI PF01202.22 EGC30782.1 - 0.13 12.3 1.8 10 6.2 0.0 3.2 3 0 0 3 3 3 0 Shikimate kinase RsgA_GTPase PF03193.16 EGC30782.1 - 1.3 8.9 6.1 1.8 8.4 0.0 3.8 4 0 0 4 4 3 0 RsgA GTPase DUF2040 PF09745.9 EGC30783.1 - 1.1e-31 109.4 28.2 1.1e-31 109.4 28.2 1.6 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) p450 PF00067.22 EGC30784.1 - 1.2e-91 307.8 0.7 1.4e-91 307.6 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 BtrH_N PF14399.6 EGC30784.1 - 0.00024 21.4 0.1 0.00045 20.5 0.1 1.4 1 0 0 1 1 1 1 Butirosin biosynthesis protein H, N-terminal Cullin PF00888.22 EGC30785.1 - 3.9e-179 597.2 36.5 4.7e-179 597.0 36.5 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGC30785.1 - 9.8e-24 83.2 0.4 9.8e-24 83.2 0.4 4.1 4 0 0 4 4 4 1 Cullin protein neddylation domain PCI PF01399.27 EGC30785.1 - 0.14 12.6 3.7 0.33 11.5 0.1 3.2 3 0 0 3 3 3 0 PCI domain DUF4494 PF14902.6 EGC30785.1 - 0.2 11.5 4.2 0.3 10.9 1.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4494) DALR_1 PF05746.15 EGC30785.1 - 1.1 9.5 4.2 6.2 7.0 0.1 3.0 2 0 0 2 2 2 0 DALR anticodon binding domain Peptidase_C1 PF00112.23 EGC30787.1 - 6.4e-42 144.1 3.8 6.4e-42 144.1 3.8 1.6 2 0 0 2 2 2 1 Papain family cysteine protease CAP PF00188.26 EGC30787.1 - 6e-14 53.0 6.8 1.8e-13 51.4 6.8 1.9 1 0 0 1 1 1 1 Cysteine-rich secretory protein family PfkB PF00294.24 EGC30788.1 - 1.8e-66 224.5 0.4 2.1e-66 224.3 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Alpha_Helical PF18489.1 EGC30788.1 - 0.071 13.3 0.1 0.17 12.1 0.1 1.6 1 0 0 1 1 1 0 Alpha helical domain DUF5061 PF16587.5 EGC30788.1 - 0.099 12.7 0.1 8.7 6.5 0.0 2.3 2 0 0 2 2 2 0 17 kDa common-antigen outer membrane protein TIG PF01833.24 EGC30790.1 - 0.00045 20.2 14.0 0.019 15.1 1.2 4.1 4 0 0 4 4 4 3 IPT/TIG domain LRR_4 PF12799.7 EGC30790.1 - 0.059 13.8 18.8 0.91 10.0 2.7 5.1 3 3 2 5 5 5 0 Leucine Rich repeats (2 copies) Glutaredoxin2_C PF04399.13 EGC30790.1 - 0.12 12.2 0.4 0.31 10.9 0.1 1.8 2 0 0 2 2 2 0 Glutaredoxin 2, C terminal domain LRR_8 PF13855.6 EGC30790.1 - 0.24 11.2 14.5 0.075 12.8 1.2 4.9 4 1 0 4 4 4 0 Leucine rich repeat zf-RING_2 PF13639.6 EGC30791.1 - 2e-09 37.6 9.6 4.1e-09 36.6 9.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC30791.1 - 1.5e-08 34.3 7.0 3e-08 33.4 7.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC30791.1 - 1.4e-07 31.2 10.3 3.3e-07 30.1 10.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC30791.1 - 2.2e-07 30.6 8.7 4.3e-07 29.7 8.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC30791.1 - 4.4e-05 23.4 3.3 5.8e-05 23.0 2.1 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC30791.1 - 0.00023 21.4 8.6 0.00093 19.4 8.6 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC30791.1 - 0.00089 19.2 9.1 0.002 18.0 9.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC30791.1 - 0.016 15.0 7.5 0.037 13.9 7.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC30791.1 - 0.029 14.5 8.7 0.067 13.4 8.7 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC30791.1 - 0.037 14.1 1.8 0.082 13.0 1.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC30791.1 - 0.2 11.5 12.3 0.043 13.6 8.6 1.9 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGC30791.1 - 0.2 11.7 5.7 0.55 10.3 5.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 EGC30791.1 - 0.36 10.6 6.3 0.87 9.4 6.3 1.7 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGC30791.1 - 0.86 9.7 6.2 1.9 8.6 6.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zinc_ribbon_9 PF14369.6 EGC30791.1 - 1 9.7 7.5 0.85 9.9 3.7 2.5 2 0 0 2 2 2 0 zinc-ribbon SPX PF03105.19 EGC30791.1 - 3.3 7.5 35.5 4.6 7.1 35.5 1.1 1 0 0 1 1 1 0 SPX domain BRCT PF00533.26 EGC30792.1 - 0.0072 16.7 0.3 0.05 14.0 0.1 2.7 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGC30792.1 - 0.031 14.1 0.1 0.13 12.1 0.1 2.1 1 0 0 1 1 1 0 Regulator of Ty1 transposition protein 107 BRCT domain Trypan_PARP PF05887.11 EGC30792.1 - 0.1 12.6 4.7 0.21 11.6 4.7 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4996 PF16387.5 EGC30792.1 - 0.55 10.7 2.1 0.87 10.1 0.1 2.3 3 0 0 3 3 3 0 Domain of unknown function Leo1 PF04004.13 EGC30793.1 - 5.7e-44 149.9 0.6 5.7e-44 149.9 0.6 3.2 3 1 0 3 3 3 1 Leo1-like protein Nucleoporin_FG PF13634.6 EGC30793.1 - 0.24 12.3 1.5 4.7 8.1 0.0 3.0 3 0 0 3 3 3 0 Nucleoporin FG repeat region Podoplanin PF05808.11 EGC30794.1 - 0.035 14.2 0.3 0.071 13.2 0.0 1.8 2 0 0 2 2 2 0 Podoplanin PTP_tm PF18861.1 EGC30794.1 - 0.042 13.8 0.9 0.15 12.1 0.0 2.1 2 0 0 2 2 2 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J LapA_dom PF06305.11 EGC30794.1 - 0.058 13.2 2.2 0.19 11.5 1.7 1.9 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain Palm_thioest PF02089.15 EGC30795.1 - 2.6e-84 282.9 0.0 3e-84 282.7 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF915 PF06028.11 EGC30795.1 - 0.022 14.1 0.0 0.05 12.9 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EGC30795.1 - 0.029 13.9 0.0 0.15 11.6 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) bPH_4 PF06713.11 EGC30795.1 - 0.037 14.1 0.0 0.12 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain FSH1 PF03959.13 EGC30795.1 - 0.13 11.9 0.0 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Serine hydrolase (FSH1) FAD_binding_4 PF01565.23 EGC30796.1 - 2.1e-25 89.1 0.1 4e-25 88.2 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC30796.1 - 7.4e-15 54.8 4.4 1.5e-14 53.8 4.4 1.6 1 0 0 1 1 1 1 Berberine and berberine like Nyv1_N PF09426.10 EGC30796.1 - 0.033 14.2 0.6 0.033 14.2 0.6 2.5 2 1 1 3 3 3 0 Vacuolar R-SNARE Nyv1 N terminal BBE PF08031.12 EGC30797.1 - 1.4e-16 60.3 7.4 2e-16 59.8 5.9 2.2 2 0 0 2 2 2 1 Berberine and berberine like DUF928 PF06051.12 EGC30797.1 - 0.08 12.8 0.1 0.13 12.1 0.1 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) OST3_OST6 PF04756.13 EGC30798.1 - 1.1e-41 143.2 10.3 1.7e-41 142.5 10.3 1.2 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Deltameth_res PF16020.5 EGC30798.1 - 0.0013 18.6 1.8 0.028 14.3 0.1 3.3 3 0 0 3 3 3 1 Deltamethrin resistance DUF1772 PF08592.11 EGC30798.1 - 0.014 15.8 1.7 0.1 12.9 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF1772) SdpI PF13630.6 EGC30798.1 - 0.045 13.9 0.6 0.045 13.9 0.6 3.0 3 0 0 3 3 3 0 SdpI/YhfL protein family AtpR PF12966.7 EGC30798.1 - 2 8.9 10.5 0.52 10.8 1.9 3.1 4 0 0 4 4 4 0 N-ATPase, AtpR subunit OppC_N PF12911.7 EGC30798.1 - 4.4 7.3 11.6 0.85 9.6 0.6 3.3 4 1 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C SUIM_assoc PF16619.5 EGC30799.1 - 1.9e-05 24.6 20.0 0.0025 17.8 11.1 3.9 4 0 0 4 4 4 2 Unstructured region C-term to UIM in Ataxin3 PEX11 PF05648.14 EGC30799.1 - 0.0014 18.1 3.8 0.005 16.3 3.8 1.9 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HEAT PF02985.22 EGC30799.1 - 0.0037 17.4 0.0 0.23 11.8 0.0 3.9 4 0 0 4 4 3 1 HEAT repeat Cohesin_HEAT PF12765.7 EGC30799.1 - 0.031 14.6 0.1 0.092 13.1 0.1 1.8 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion ABC2_membrane_2 PF12679.7 EGC30799.1 - 0.16 11.2 1.9 2 7.6 0.5 2.3 2 0 0 2 2 2 0 ABC-2 family transporter protein DUF3299 PF11736.8 EGC30799.1 - 0.17 11.9 5.0 0.042 13.9 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) TAF6_C PF07571.13 EGC30799.1 - 0.24 11.7 0.9 26 5.2 0.0 3.8 3 0 0 3 3 3 0 TAF6 C-terminal HEAT repeat domain CCDC53 PF10152.9 EGC30799.1 - 0.92 9.9 13.9 0.68 10.3 5.6 3.0 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex DDE_Tnp_IS66 PF03050.14 EGC30799.1 - 1.4 8.3 6.6 2.7 7.4 6.6 1.4 1 0 0 1 1 1 0 Transposase IS66 family Glyco_transf_9 PF01075.17 EGC30799.1 - 5 6.4 6.7 10 5.3 2.6 2.3 2 0 0 2 2 2 0 Glycosyltransferase family 9 (heptosyltransferase) Pep1_7 PF17232.2 EGC30799.1 - 7.3 7.1 8.1 18 5.9 1.5 4.4 4 0 0 4 4 4 0 Elicitor peptide 1-7 FNIP PF05725.12 EGC30801.1 - 2.2e-13 50.2 13.4 3.1e-06 27.2 0.5 5.8 3 2 3 6 6 6 5 FNIP Repeat zf-B_box PF00643.24 EGC30801.1 - 8.6e-06 25.8 1.6 8.6e-06 25.8 1.6 2.2 2 0 0 2 2 2 1 B-box zinc finger Chalcone_N PF18232.1 EGC30801.1 - 0.013 15.9 0.1 0.039 14.4 0.1 1.8 1 0 0 1 1 1 0 Chalcone isomerase N-terminal domain MFA1_2 PF17317.2 EGC30801.1 - 7.3 6.5 7.8 0.91 9.4 2.6 2.1 2 0 0 2 2 2 0 Mating hormone A-factor 1&2 PH PF00169.29 EGC30802.1 - 6e-11 42.8 0.1 1.3e-10 41.7 0.1 1.6 1 0 0 1 1 1 1 PH domain YpjP PF14005.6 EGC30802.1 - 0.026 14.6 0.2 0.11 12.5 0.2 2.2 2 0 0 2 2 2 0 YpjP-like protein PH_8 PF15409.6 EGC30802.1 - 0.029 14.7 0.0 1.3 9.4 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain XLF PF09302.11 EGC30803.1 - 1.4e-09 38.3 5.8 1.4e-09 38.3 5.8 3.3 3 1 1 4 4 4 1 XLF-Cernunnos, XRcc4-like factor, NHEJ component WH2 PF02205.20 EGC30804.1 - 0.00037 20.2 0.1 0.0008 19.2 0.1 1.6 1 0 0 1 1 1 1 WH2 motif UPF0767 PF15990.5 EGC30804.1 - 0.034 14.3 1.2 0.087 13.0 1.2 1.6 1 0 0 1 1 1 0 UPF0767 family ABC1 PF03109.16 EGC30805.1 - 4.1e-27 94.7 0.0 9.9e-27 93.5 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.23 EGC30805.1 - 0.16 11.8 0.1 0.32 10.9 0.1 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DEAD_2 PF06733.15 EGC30807.1 - 6e-56 188.8 1.2 6e-56 188.8 1.2 2.1 3 0 0 3 3 3 1 DEAD_2 Helicase_C_2 PF13307.6 EGC30807.1 - 3.6e-46 157.5 0.3 1.6e-45 155.3 0.0 2.3 3 0 0 3 3 3 1 Helicase C-terminal domain HBB PF06777.11 EGC30807.1 - 1.5e-37 129.2 0.2 1.3e-33 116.3 0.1 2.9 3 0 0 3 3 3 2 Helical and beta-bridge domain ResIII PF04851.15 EGC30807.1 - 0.00013 22.1 0.4 0.0019 18.2 0.0 2.6 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.6 EGC30807.1 - 0.027 14.7 0.1 7.4 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF3439 PF11921.8 EGC30807.1 - 0.86 9.6 6.8 1.9 8.5 6.8 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MIR PF02815.19 EGC30808.1 - 1.5e-16 60.8 0.1 1.1e-08 35.1 0.0 3.1 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.11 EGC30808.1 - 0.011 14.9 0.1 0.083 12.1 0.0 2.3 1 1 1 2 2 2 0 Inositol 1,4,5-trisphosphate/ryanodine receptor DUF4813 PF16072.5 EGC30808.1 - 0.1 12.3 0.7 0.14 11.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4813) NRDE-2 PF08424.10 EGC30809.1 - 2.1e-98 329.4 14.8 2.1e-98 329.4 14.8 4.0 4 0 0 4 4 4 2 NRDE-2, necessary for RNA interference TPR_14 PF13428.6 EGC30809.1 - 0.015 16.0 0.0 3.2 8.8 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat Histone PF00125.24 EGC30810.1 - 1.3e-21 77.3 2.2 1.6e-21 77.0 2.2 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC30810.1 - 3.4e-06 27.2 0.2 3.4e-06 27.2 0.2 1.7 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGC30810.1 - 0.002 18.6 0.0 0.0043 17.5 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF4364 PF14277.6 EGC30810.1 - 0.01 15.6 0.3 0.013 15.2 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4364) CENP-T_C PF15511.6 EGC30810.1 - 0.012 15.8 0.8 0.014 15.5 0.3 1.5 1 1 1 2 2 2 0 Centromere kinetochore component CENP-T histone fold PIP5K PF01504.18 EGC30811.1 - 7.7e-59 199.2 15.2 1.6e-58 198.1 5.4 2.9 2 1 0 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.11 EGC30811.1 - 7.4e-19 68.0 6.2 7.4e-19 68.0 6.2 2.3 2 1 0 2 2 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 EGC30811.1 - 1.5e-17 63.7 11.0 1.6e-16 60.3 11.0 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGC30811.1 - 1.9e-09 37.2 6.2 3.1e-09 36.5 6.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.21 EGC30811.1 - 1.3e-08 34.6 4.2 1.9e-08 34.0 4.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) 7TM_GPCR_Srsx PF10320.9 EGC30811.1 - 8.6e-06 25.3 7.3 1.3e-05 24.7 7.3 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx GPR_Gpa2_C PF11970.8 EGC30811.1 - 0.00011 22.3 1.2 0.0075 16.3 0.1 2.7 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term DUF420 PF04238.12 EGC30811.1 - 0.0089 16.3 1.7 0.61 10.4 0.1 2.5 1 1 0 2 2 2 1 Protein of unknown function (DUF420) Presenilin PF01080.17 EGC30811.1 - 0.016 14.0 1.3 0.027 13.3 1.3 1.4 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EGC30811.1 - 0.54 9.5 4.0 0.99 8.7 4.0 1.3 1 0 0 1 1 1 0 NOA36 protein DUF2569 PF10754.9 EGC30811.1 - 1.6 9.2 8.5 4.2 7.8 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2569) Macoilin PF09726.9 EGC30811.1 - 4.3 5.8 15.5 6.6 5.2 15.5 1.2 1 0 0 1 1 1 0 Macoilin family Sec63 PF02889.16 EGC30813.1 - 1.7e-138 460.0 12.0 3e-79 265.8 2.8 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGC30813.1 - 1.5e-52 177.9 0.5 1.9e-27 96.2 0.3 3.2 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.15 EGC30813.1 - 4e-26 92.0 11.6 1.1e-15 58.1 0.2 3.6 3 1 0 3 3 2 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGC30813.1 - 6.3e-19 68.4 0.1 2.9e-08 34.0 0.1 4.1 2 1 0 2 2 2 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGC30813.1 - 5e-07 29.6 0.0 0.0045 16.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain T2SSE PF00437.20 EGC30813.1 - 1.6e-05 24.1 0.0 0.042 12.9 0.0 2.8 3 0 0 3 3 3 2 Type II/IV secretion system protein AAA_22 PF13401.6 EGC30813.1 - 2.7e-05 24.5 1.1 0.19 12.0 0.1 3.4 2 2 0 2 2 2 2 AAA domain AAA_19 PF13245.6 EGC30813.1 - 3.9e-05 24.0 0.1 0.032 14.6 0.1 2.8 2 0 0 2 2 2 2 AAA domain PhoH PF02562.16 EGC30813.1 - 0.00015 21.3 0.1 0.41 10.1 0.0 3.0 3 0 0 3 3 3 2 PhoH-like protein AAA PF00004.29 EGC30813.1 - 0.00043 20.7 2.0 0.43 11.0 0.0 4.1 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) Helicase_PWI PF18149.1 EGC30813.1 - 0.0041 17.3 0.4 0.023 14.8 0.0 2.5 2 0 0 2 2 2 1 N-terminal helicase PWI domain AAA_7 PF12775.7 EGC30813.1 - 0.011 15.3 0.2 4.1 6.9 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region DUF4327 PF14217.6 EGC30813.1 - 0.029 14.5 0.4 5.7 7.2 0.0 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4327) AAA_16 PF13191.6 EGC30813.1 - 0.11 12.9 0.0 1.6 9.1 0.0 2.8 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.17 EGC30813.1 - 0.11 12.2 0.1 11 5.7 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_11 PF13086.6 EGC30813.1 - 0.38 10.5 0.0 0.38 10.5 0.0 4.0 4 2 2 6 6 6 0 AAA domain RhoGEF PF00621.20 EGC30814.1 - 1.2e-36 126.6 15.1 1.2e-36 126.6 15.1 2.8 2 1 0 2 2 2 1 RhoGEF domain DnaJ PF00226.31 EGC30815.1 - 4.8e-29 100.3 3.0 4.8e-29 100.3 3.0 1.7 2 0 0 2 2 2 1 DnaJ domain PhageMin_Tail PF10145.9 EGC30815.1 - 0.028 14.3 0.1 0.082 12.8 0.1 1.6 2 0 0 2 2 2 0 Phage-related minor tail protein NPM1-C PF16276.5 EGC30815.1 - 0.031 14.2 0.0 5 7.2 0.0 2.7 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain SAS4 PF15460.6 EGC30815.1 - 0.21 11.7 2.5 0.35 11.0 0.5 2.0 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 Glutaredoxin PF00462.24 EGC30816.1 - 8.6e-18 64.3 0.2 1.7e-17 63.3 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.6 EGC30816.1 - 0.00026 21.0 0.0 0.00038 20.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_2 PF13098.6 EGC30816.1 - 0.0046 17.4 0.2 0.015 15.7 0.2 1.8 1 1 0 1 1 1 1 Thioredoxin-like domain DUF836 PF05768.14 EGC30816.1 - 0.0057 17.1 0.1 0.0089 16.4 0.1 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) TraF PF13728.6 EGC30816.1 - 0.0066 16.3 0.0 0.009 15.8 0.0 1.1 1 0 0 1 1 1 1 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EGC30816.1 - 0.019 15.1 0.4 0.74 9.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin DSBA PF01323.20 EGC30816.1 - 0.04 13.7 0.9 4.8 6.9 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain Nucleoside_tran PF01733.18 EGC30817.1 - 1e-48 166.4 21.6 1e-48 166.4 21.6 2.5 1 1 1 2 2 2 1 Nucleoside transporter Ac76 PF05814.11 EGC30817.1 - 9.4 6.3 11.4 26 4.9 3.1 4.1 3 1 0 3 3 3 0 Orf76 (Ac76) AMMECR1 PF01871.17 EGC30818.1 - 1.4e-46 158.1 0.0 1.7e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 ADH_zinc_N PF00107.26 EGC30819.1 - 1.4e-26 93.0 0.0 2.4e-26 92.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC30819.1 - 4.3e-19 69.9 0.0 1.1e-18 68.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC30819.1 - 0.00013 21.8 0.0 0.00023 21.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EAL PF00563.20 EGC30819.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 EAL domain Cullin_binding PF03556.15 EGC30820.1 - 2e-30 105.7 2.2 2e-30 105.7 2.2 2.5 2 1 1 3 3 3 1 Cullin binding UBA_4 PF14555.6 EGC30820.1 - 4.2e-11 42.5 0.0 8.9e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain adh_short PF00106.25 EGC30821.1 - 1.2e-22 80.3 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC30821.1 - 9.7e-10 38.4 0.0 1.2e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF19 PF01579.18 EGC30821.1 - 0.021 14.6 3.9 0.61 9.9 0.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF19) KR PF08659.10 EGC30821.1 - 0.03 14.2 0.0 0.062 13.2 0.0 1.4 1 0 0 1 1 1 0 KR domain THP2 PF09432.10 EGC30821.1 - 0.057 13.5 0.1 1.4 8.9 0.1 2.3 1 1 1 2 2 2 0 Tho complex subunit THP2 UQ_con PF00179.26 EGC30822.1 - 3.1e-18 65.8 0.0 3.4e-18 65.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Ferlin_C PF16165.5 EGC30823.1 - 0.23 11.4 7.6 0.31 11.0 7.6 1.2 1 0 0 1 1 1 0 Ferlin C-terminus Band_3_cyto PF07565.13 EGC30823.1 - 0.24 11.2 1.9 0.31 10.8 1.9 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Presenilin PF01080.17 EGC30823.1 - 3 6.5 5.9 3.4 6.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGC30823.1 - 8.4 5.5 6.9 9.9 5.3 6.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter IF4E PF01652.18 EGC30825.1 - 7e-41 139.7 0.2 1.6e-40 138.5 0.2 1.6 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Annexin PF00191.20 EGC30827.1 - 8.8e-21 73.8 0.6 2.6e-08 33.8 0.0 3.1 3 0 0 3 3 3 3 Annexin Enterotoxin_b PF01376.18 EGC30829.1 - 0.37 11.0 1.8 6 7.1 0.4 2.9 2 0 0 2 2 2 0 Heat-labile enterotoxin beta chain FNIP PF05725.12 EGC30830.1 - 3.8e-52 174.2 58.5 3.2e-13 49.6 1.1 9.3 3 2 8 11 11 11 10 FNIP Repeat DUF1769 PF08588.10 EGC30830.1 - 0.0017 18.5 3.4 7.2 6.9 0.2 5.9 4 2 3 7 7 7 2 Protein of unknown function (DUF1769) GpcrRhopsn4 PF10192.9 EGC30831.1 - 2.9e-61 207.1 35.1 4e-61 206.7 35.1 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Cyt_bd_oxida_II PF02322.15 EGC30831.1 - 0.55 9.5 26.7 1.2 8.4 26.7 1.6 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II PIRT PF15099.6 EGC30831.1 - 4.9 6.7 13.4 0.36 10.4 2.1 2.4 1 1 2 3 3 3 0 Phosphoinositide-interacting protein family TIG PF01833.24 EGC30832.1 - 5e-11 42.5 5.6 1.2e-08 34.9 0.3 5.1 6 0 0 6 6 6 3 IPT/TIG domain LRR_8 PF13855.6 EGC30832.1 - 0.0049 16.6 8.3 2.9 7.7 0.0 4.5 3 1 0 3 3 3 3 Leucine rich repeat Fe-S_biosyn PF01521.20 EGC30833.1 - 5e-14 52.4 0.5 9.5e-14 51.5 0.5 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DUF2222 PF09984.9 EGC30833.1 - 0.11 12.4 5.8 0.15 11.9 5.8 1.2 1 0 0 1 1 1 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) DUF655 PF04919.12 EGC30835.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF655) Sigma54_DBD PF04552.13 EGC30835.1 - 0.16 11.7 0.0 0.2 11.3 0.0 1.1 1 0 0 1 1 1 0 Sigma-54, DNA binding domain Mx_ML PF17536.2 EGC30836.1 - 0.028 14.2 0.4 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 Matrix and Matrix long proteins N-terminal DDE_Tnp_4 PF13359.6 EGC30837.1 - 1.5e-06 28.0 5.2 0.00059 19.5 1.4 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC30837.1 - 0.0044 16.7 0.3 0.0053 16.4 0.3 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EGC30837.1 - 0.016 14.9 0.0 0.03 14.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease HTH_psq PF05225.16 EGC30837.1 - 0.021 14.5 0.0 0.37 10.6 0.0 2.3 2 0 0 2 2 2 0 helix-turn-helix, Psq domain SWI2_SNF2 PF18766.1 EGC30838.1 - 6.7e-23 81.5 0.4 6.7e-23 81.5 0.4 2.5 2 0 0 2 2 2 1 SWI2/SNF2 ATPase ResIII PF04851.15 EGC30838.1 - 4.9e-11 42.9 1.5 4.9e-11 42.9 1.5 3.8 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC30838.1 - 1.2e-06 28.5 0.5 1.2e-06 28.5 0.5 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Surp PF01805.20 EGC30838.1 - 4.4e-06 26.6 0.0 1.1e-05 25.3 0.0 1.7 1 0 0 1 1 1 1 Surp module NAD_binding_1 PF00175.21 EGC30838.1 - 0.043 14.5 3.9 8.6 7.1 2.1 2.9 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain RhoGAP PF00620.27 EGC30840.1 - 3.3e-31 108.2 0.0 7.8e-31 106.9 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain RPEL PF02755.15 EGC30840.1 - 0.079 12.7 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 RPEL repeat Glyco_hydro_20 PF00728.22 EGC30841.1 - 1.2e-71 241.9 1.3 5e-71 239.9 1.3 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGC30841.1 - 1.3e-05 25.9 0.0 3.1e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Nse5 PF08691.10 EGC30841.1 - 0.00021 20.1 4.0 0.00037 19.3 4.0 1.3 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 DUF5345 PF17280.2 EGC30842.1 - 0.049 13.6 0.0 0.07 13.1 0.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5345) BTB_2 PF02214.22 EGC30843.1 - 1e-20 73.9 0.1 3.1e-20 72.3 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EGC30843.1 - 1e-07 32.0 0.1 2.6e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain SUIM_assoc PF16619.5 EGC30843.1 - 0.0003 20.8 1.0 0.009 16.1 0.1 2.8 2 1 0 2 2 2 1 Unstructured region C-term to UIM in Ataxin3 TFIIA PF03153.13 EGC30843.1 - 0.029 14.4 14.3 0.038 14.0 14.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit 7tm_2 PF00002.24 EGC30844.1 - 0.00026 20.3 12.3 0.0005 19.4 12.3 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 EGC30844.1 - 0.0017 17.4 19.5 0.0043 16.2 19.5 1.7 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region ECF-ribofla_trS PF07155.12 EGC30844.1 - 0.0055 16.7 4.9 0.0055 16.7 4.9 2.1 2 0 0 2 2 2 1 ECF-type riboflavin transporter, S component Dicty_CAR PF05462.11 EGC30844.1 - 0.52 9.4 20.3 0.63 9.1 17.3 2.2 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor Pkinase PF00069.25 EGC30845.1 - 4.6e-71 239.3 0.0 7.8e-71 238.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30845.1 - 5.6e-36 124.1 0.0 8.8e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGC30845.1 - 3.1e-16 58.9 0.0 5.4e-16 58.1 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EGC30845.1 - 3.1e-06 26.7 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC30845.1 - 0.00071 19.6 0.0 0.027 14.4 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGC30845.1 - 0.0095 14.9 0.1 0.0095 14.9 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Choline_kinase PF01633.20 EGC30845.1 - 0.021 14.4 0.1 0.058 13.0 0.1 1.7 1 0 0 1 1 1 0 Choline/ethanolamine kinase CBS PF00571.28 EGC30846.1 - 5.5e-28 97.2 0.4 1.5e-10 41.3 0.1 4.3 4 0 0 4 4 4 4 CBS domain PP2C_2 PF13672.6 EGC30847.1 - 0.00055 19.6 0.1 0.0013 18.4 0.1 1.6 2 0 0 2 2 2 1 Protein phosphatase 2C Host_attach PF10116.9 EGC30848.1 - 0.015 15.9 0.3 0.017 15.7 0.3 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells DUF2052 PF09747.9 EGC30848.1 - 0.034 14.3 9.0 0.037 14.1 9.0 1.1 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) HSP90 PF00183.18 EGC30848.1 - 0.035 13.0 16.3 0.042 12.8 16.3 1.0 1 0 0 1 1 1 0 Hsp90 protein HABP4_PAI-RBP1 PF04774.15 EGC30848.1 - 0.047 14.5 12.3 0.057 14.3 12.3 1.1 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family Secretin_N_2 PF07655.13 EGC30848.1 - 0.34 11.5 17.3 0.048 14.2 13.5 1.5 1 1 1 2 2 2 0 Secretin N-terminal domain LRRC37AB_C PF14914.6 EGC30848.1 - 0.35 10.8 6.3 0.38 10.7 6.3 1.2 1 0 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain RNA_pol_Rbc25 PF08292.12 EGC30848.1 - 0.68 10.2 6.4 0.87 9.8 6.4 1.1 1 0 0 1 1 1 0 RNA polymerase III subunit Rpc25 DUF4834 PF16118.5 EGC30848.1 - 0.81 10.7 8.3 1 10.4 8.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EIIBC-GUT_N PF03612.14 EGC30848.1 - 1.6 8.5 5.7 1.6 8.4 5.7 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Coilin_N PF15862.5 EGC30848.1 - 1.8 8.4 15.7 2.1 8.1 15.7 1.1 1 0 0 1 1 1 0 Coilin N-terminus DUF3438 PF11920.8 EGC30848.1 - 1.9 7.7 5.1 2.2 7.5 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3438) CLN3 PF02487.17 EGC30848.1 - 2.4 7.1 5.2 2.4 7.1 5.2 1.0 1 0 0 1 1 1 0 CLN3 protein Connexin PF00029.19 EGC30848.1 - 2.9 7.6 6.0 3 7.5 6.0 1.1 1 0 0 1 1 1 0 Connexin Folate_carrier PF01770.18 EGC30848.1 - 4 6.1 5.5 4.1 6.1 5.5 1.1 1 0 0 1 1 1 0 Reduced folate carrier OATP PF03137.20 EGC30848.1 - 4.4 5.5 5.3 4.9 5.3 5.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Tim54 PF11711.8 EGC30848.1 - 4.5 6.0 12.2 5 5.8 12.2 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3464 PF11947.8 EGC30848.1 - 4.8 6.9 9.4 5.2 6.8 9.4 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Neur_chan_memb PF02932.16 EGC30848.1 - 6 6.9 6.3 6.1 6.8 6.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region GCD14 PF08704.10 EGC30848.1 - 6.1 6.4 8.0 6.6 6.3 8.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Presenilin PF01080.17 EGC30848.1 - 6.3 5.4 11.2 7.1 5.3 11.2 1.0 1 0 0 1 1 1 0 Presenilin Serinc PF03348.15 EGC30848.1 - 7.1 5.4 6.4 8.3 5.2 6.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) MAP17 PF15807.5 EGC30848.1 - 9 6.5 11.9 10 6.4 11.9 1.2 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 ALMT PF11744.8 EGC30848.1 - 9.2 5.0 10.2 9.8 4.9 10.2 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 EGC30848.1 - 9.3 5.7 11.7 12 5.3 11.7 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 60KD_IMP PF02096.20 EGC30849.1 - 7.1e-20 71.6 2.8 1.4e-19 70.6 2.8 1.5 1 0 0 1 1 1 1 60Kd inner membrane protein Perilipin PF03036.16 EGC30849.1 - 0.049 12.7 0.0 0.085 11.9 0.0 1.3 1 0 0 1 1 1 0 Perilipin family RPN6_N PF18055.1 EGC30850.1 - 2.2e-25 89.3 1.1 3.4e-24 85.5 0.0 2.8 3 0 0 3 3 3 1 26S proteasome regulatory subunit RPN6 N-terminal domain PCI PF01399.27 EGC30850.1 - 1.8e-17 63.8 0.9 1.7e-16 60.7 0.8 2.5 2 0 0 2 2 2 1 PCI domain RPN6_C_helix PF18503.1 EGC30850.1 - 9.9e-12 44.4 0.1 2.7e-11 43.0 0.1 1.8 1 0 0 1 1 1 1 26S proteasome subunit RPN6 C-terminal helix domain RPN7 PF10602.9 EGC30850.1 - 0.055 13.2 0.8 0.15 11.8 0.1 2.4 2 1 0 2 2 2 0 26S proteasome subunit RPN7 TPR_12 PF13424.6 EGC30850.1 - 0.066 13.5 0.9 2.6 8.4 0.3 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat EloA-BP1 PF15870.5 EGC30851.1 - 1.1e-09 38.8 0.2 1.1e-09 38.8 0.2 3.1 3 0 0 3 3 3 1 ElonginA binding-protein 1 PI3_PI4_kinase PF00454.27 EGC30852.1 - 0.0014 18.5 14.3 0.0041 17.0 0.3 4.5 4 1 1 5 5 5 2 Phosphatidylinositol 3- and 4-kinase ABC2_membrane PF01061.24 EGC30853.1 - 1.3e-39 135.8 24.6 1.3e-39 135.8 24.6 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC30853.1 - 1.8e-25 90.1 0.0 5e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC30853.1 - 2.7e-05 24.1 8.1 0.0045 16.9 0.2 3.0 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system DUF2722 PF10846.8 EGC30853.1 - 0.0088 15.0 11.8 0.013 14.5 11.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) RsgA_GTPase PF03193.16 EGC30853.1 - 0.055 13.4 0.2 0.13 12.2 0.2 1.5 1 0 0 1 1 1 0 RsgA GTPase ABC2_membrane_2 PF12679.7 EGC30853.1 - 0.06 12.6 4.4 0.14 11.4 4.4 1.6 1 0 0 1 1 1 0 ABC-2 family transporter protein AAA_25 PF13481.6 EGC30853.1 - 0.1 12.1 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC30853.1 - 0.73 10.4 3.6 0.74 10.4 0.0 2.6 3 0 0 3 3 2 0 AAA domain Menin PF05053.13 EGC30853.1 - 3.6 5.8 10.1 5.1 5.3 10.1 1.1 1 0 0 1 1 1 0 Menin NST1 PF13945.6 EGC30853.1 - 3.9 7.5 15.4 7.9 6.5 15.4 1.5 1 0 0 1 1 1 0 Salt tolerance down-regulator Laminin_EGF PF00053.24 EGC30853.1 - 5 7.3 23.3 0.18 12.0 6.2 3.4 2 1 1 3 3 3 0 Laminin EGF domain Proteasome PF00227.26 EGC30855.1 - 3.7e-63 212.5 0.0 4.6e-63 212.2 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC30855.1 - 7.2e-13 47.9 0.3 1.6e-12 46.8 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pet191_N PF10203.9 EGC30856.1 - 2.6e-21 75.7 4.0 4.1e-21 75.1 4.0 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGC30856.1 - 4.8e-05 23.3 4.2 0.0028 17.6 1.3 2.5 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, CHCH PF06747.13 EGC30856.1 - 0.067 13.3 6.4 0.07 13.3 1.4 2.7 2 0 0 2 2 2 0 CHCH domain Podoplanin PF05808.11 EGC30858.1 - 0.0016 18.6 0.9 0.043 13.9 0.0 2.5 2 0 0 2 2 2 1 Podoplanin Fil_haemagg PF05594.14 EGC30858.1 - 0.0022 18.5 1.6 0.0022 18.5 1.6 5.2 5 3 0 5 5 5 2 Haemagluttinin repeat PP2C PF00481.21 EGC30859.1 - 6.5e-49 166.9 0.1 6.5e-49 166.9 0.1 2.8 3 1 1 4 4 4 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGC30859.1 - 0.00011 21.9 0.0 0.00037 20.2 0.0 1.9 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGC30859.1 - 0.00024 21.1 0.0 0.091 12.7 0.0 2.4 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF3450 PF11932.8 EGC30859.1 - 0.2 10.9 24.9 0.52 9.6 7.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) COG5 PF10392.9 EGC30859.1 - 0.59 10.3 20.8 0.24 11.6 8.0 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 MLD PF11647.8 EGC30859.1 - 1.1 9.5 6.8 1.6 9.1 1.8 3.5 2 1 1 3 3 3 0 Membrane Localization Domain DUF4407 PF14362.6 EGC30859.1 - 3.3 7.0 14.2 9.2 5.5 14.2 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) SUIM_assoc PF16619.5 EGC30860.1 - 3 8.0 6.9 0.89 9.7 0.5 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 GCV_H PF01597.19 EGC30862.1 - 8.1e-16 58.0 1.7 1.8e-15 56.9 1.7 1.6 1 1 0 1 1 1 1 Glycine cleavage H-protein NQRA PF05896.11 EGC30862.1 - 0.048 13.1 0.0 0.053 13.0 0.0 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) RnfC_N PF13375.6 EGC30862.1 - 0.13 12.2 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain Tubulin PF00091.25 EGC30863.1 - 2.4e-66 223.7 0.0 4.5e-66 222.8 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGC30863.1 - 2.8e-45 153.6 0.8 4.3e-45 152.9 0.8 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGC30863.1 - 0.0085 15.8 0.0 0.019 14.7 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGC30863.1 - 0.15 11.2 0.0 0.32 10.1 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Peptidase_C1 PF00112.23 EGC30864.1 - 8e-73 245.1 6.3 9.6e-73 244.9 6.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGC30864.1 - 1.8e-06 27.0 1.0 0.00021 20.2 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family F-box_5 PF18511.1 EGC30865.1 - 0.18 11.4 0.4 0.67 9.6 0.1 2.0 2 0 0 2 2 2 0 F-box EF-hand_12 PF17901.1 EGC30866.1 - 2.9e-32 111.0 1.4 7.7e-32 109.6 1.4 1.7 1 0 0 1 1 1 1 EF-hand fold domain SH2 PF00017.24 EGC30866.1 - 1.7e-07 31.3 0.0 3.5e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 SH2 domain STATa_Ig PF18214.1 EGC30866.1 - 4.6e-06 26.6 0.2 8.1e-06 25.9 0.2 1.4 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain XAP5 PF04921.14 EGC30867.1 - 0.051 13.4 1.2 0.052 13.4 1.2 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Casc1_N PF15927.5 EGC30867.1 - 0.12 12.0 13.5 0.14 11.8 13.5 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DUF3915 PF13054.6 EGC30867.1 - 0.64 10.0 4.2 0.76 9.8 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) GST_N_3 PF13417.6 EGC30869.1 - 2.2e-09 37.6 0.0 4.8e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGC30869.1 - 7.8e-09 35.8 0.3 2.8e-08 34.0 0.1 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC30869.1 - 4.4e-07 30.1 0.1 1.3e-06 28.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC30869.1 - 5.2e-07 29.8 0.0 9.3e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC30869.1 - 5e-06 26.6 0.0 9.9e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC30869.1 - 0.002 18.8 0.1 0.014 16.1 0.0 2.3 1 1 1 2 2 2 1 Glutathione S-transferase N-terminal domain GST_C_2 PF13410.6 EGC30869.1 - 0.011 15.7 0.0 0.019 15.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC30870.1 - 6.8e-11 42.4 0.0 1.4e-10 41.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGC30870.1 - 2.8e-09 37.2 0.1 7.1e-09 35.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC30870.1 - 2.5e-08 34.0 0.2 4.9e-08 33.1 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC30870.1 - 2.7e-08 34.0 0.0 5.6e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC30870.1 - 6.5e-08 32.7 0.1 1.2e-07 31.8 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC30870.1 - 0.0021 18.1 0.0 0.0041 17.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF676 PF05057.14 EGC30870.1 - 0.083 12.4 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) GST_N_4 PF17172.4 EGC30870.1 - 0.12 13.1 0.0 0.33 11.7 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase N-terminal domain GST_N PF02798.20 EGC30871.1 - 2.7e-11 43.7 0.6 6.5e-11 42.4 0.2 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC30871.1 - 9.4e-11 42.0 0.0 2.2e-10 40.8 0.0 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC30871.1 - 1.4e-07 31.7 0.0 4e-07 30.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC30871.1 - 3.5e-07 30.3 0.1 1.2e-06 28.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC30871.1 - 1e-06 28.8 0.0 4.7e-06 26.7 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC30871.1 - 8.2e-05 23.3 0.2 0.00073 20.2 0.2 2.3 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGC30871.1 - 0.003 17.9 0.0 0.0068 16.7 0.0 1.7 1 0 0 1 1 1 1 Outer mitochondrial membrane transport complex protein GST_C_2 PF13410.6 EGC30871.1 - 0.0047 16.9 0.0 0.0092 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC30872.1 - 2.7e-10 40.3 0.1 5.6e-10 39.3 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC30872.1 - 2.6e-09 37.3 0.0 4.3e-09 36.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC30872.1 - 9.1e-09 35.4 0.1 1.5e-08 34.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC30872.1 - 1.2e-08 35.1 0.1 3e-08 33.9 0.1 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC30872.1 - 1.9e-06 28.0 0.0 4.4e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC30872.1 - 0.0001 22.3 0.0 0.00018 21.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC30872.1 - 0.0043 17.8 0.0 0.0076 17.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase N-terminal domain Tom37 PF10568.9 EGC30872.1 - 0.13 12.6 0.0 0.21 11.9 0.0 1.4 1 0 0 1 1 1 0 Outer mitochondrial membrane transport complex protein ADH_zinc_N PF00107.26 EGC30873.1 - 8.1e-23 80.8 0.1 1.6e-22 79.9 0.1 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC30873.1 - 4.6e-09 37.4 0.0 1.4e-08 35.9 0.0 1.8 2 1 1 3 3 3 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC30873.1 - 3.9e-07 29.9 0.0 1.5e-05 24.9 0.0 3.0 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EGC30873.1 - 0.0015 18.0 0.1 0.0022 17.5 0.1 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme ADH_N_2 PF16884.5 EGC30873.1 - 0.002 18.0 0.0 0.0068 16.3 0.0 2.0 1 1 0 1 1 1 1 N-terminal domain of oxidoreductase AlaDh_PNT_C PF01262.21 EGC30873.1 - 0.0031 16.8 0.1 0.005 16.2 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain GTP_EFTU_D2 PF03144.25 EGC30873.1 - 0.0067 16.8 0.0 0.063 13.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 PK_C PF02887.16 EGC30873.1 - 0.02 15.1 0.2 0.82 9.9 0.1 2.5 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain TrkA_N PF02254.18 EGC30873.1 - 0.058 13.7 0.1 0.12 12.6 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain zf-C3HC4_2 PF13923.6 EGC30874.1 - 2.5e-11 43.2 9.0 4.3e-11 42.5 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC30874.1 - 2.1e-10 40.3 9.5 3.3e-10 39.7 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC30874.1 - 6.7e-10 39.1 8.8 1.1e-09 38.4 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC30874.1 - 3e-08 33.4 12.0 5.7e-08 32.5 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC30874.1 - 5e-08 32.8 10.1 9.7e-08 31.9 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC30874.1 - 2.9e-06 27.2 2.0 2.9e-06 27.2 2.0 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC30874.1 - 3.4e-05 24.0 6.5 0.0001 22.5 6.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC30874.1 - 9.5e-05 22.5 9.1 0.00024 21.2 9.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC30874.1 - 0.00066 19.5 7.8 0.0017 18.2 7.8 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC30874.1 - 0.0012 18.6 6.2 0.0012 18.6 6.2 1.8 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 EGC30874.1 - 0.0025 17.9 5.4 0.0051 16.9 5.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC30874.1 - 0.0073 16.3 3.6 0.019 15.0 3.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC30874.1 - 0.0075 16.0 9.4 0.021 14.6 9.5 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain TFIIA PF03153.13 EGC30874.1 - 0.0085 16.1 29.1 0.014 15.4 29.1 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prok-E2_E PF14462.6 EGC30874.1 - 0.07 12.9 3.6 0.14 12.0 3.6 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E TMEM144 PF07857.12 EGC30874.1 - 0.08 11.9 0.5 0.22 10.5 0.5 1.7 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters zf-RING_6 PF14835.6 EGC30874.1 - 0.31 10.9 3.1 0.63 10.0 3.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein N6_N4_Mtase PF01555.18 EGC30874.1 - 0.45 10.2 6.3 0.34 10.6 0.2 2.4 2 1 0 2 2 2 0 DNA methylase FYVE PF01363.21 EGC30874.1 - 1.8 8.8 9.1 5.2 7.3 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger zf-TFIIIC PF12660.7 EGC30874.1 - 4.3 7.4 13.1 0.16 11.9 6.7 2.0 2 0 0 2 2 1 0 Putative zinc-finger of transcription factor IIIC complex DZR PF12773.7 EGC30874.1 - 6.9 6.8 8.6 22 5.2 8.6 1.8 1 1 0 1 1 1 0 Double zinc ribbon Phage_Coat_A PF05357.13 EGC30875.1 - 0.0032 17.2 0.8 0.46 10.3 0.0 3.4 2 1 0 2 2 2 2 Phage Coat Protein A MFS_1 PF07690.16 EGC30876.1 - 2.7e-39 135.1 53.7 1.1e-28 100.2 25.6 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC30876.1 - 2.5e-13 49.7 30.3 1.3e-07 30.9 6.0 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter HisKA_4TM PF16926.5 EGC30876.1 - 0.12 11.9 0.2 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 Archaeal 4TM region of histidine kinase HPS3_N PF14761.6 EGC30877.1 - 0.03 13.9 0.0 0.048 13.2 0.0 1.3 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 Ndc1_Nup PF09531.10 EGC30877.1 - 0.3 9.7 5.1 0.38 9.4 5.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pkinase_Tyr PF07714.17 EGC30878.1 - 2.1e-61 207.5 0.0 3.2e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30878.1 - 1.1e-50 172.4 0.1 7.9e-50 169.7 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain WD40 PF00400.32 EGC30878.1 - 5.6e-12 46.0 10.5 0.0021 18.8 0.4 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30878.1 - 2e-05 24.8 1.3 3.6 7.9 0.2 5.2 1 1 5 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain EPTP PF03736.17 EGC30878.1 - 0.072 13.1 0.3 0.37 10.8 0.1 2.2 1 1 1 2 2 2 0 EPTP domain FNIP PF05725.12 EGC30879.1 - 3.7e-71 235.1 53.0 5.6e-16 58.4 0.8 9.8 7 2 2 10 10 10 9 FNIP Repeat LRR_5 PF13306.6 EGC30879.1 - 0.08 12.9 3.9 1.1 9.3 0.0 3.0 2 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) Pro-kuma_activ PF09286.11 EGC30880.1 - 2.6e-34 118.6 0.0 4.2e-34 117.9 0.0 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC30880.1 - 0.00024 20.5 1.5 0.00035 19.9 0.6 1.6 2 0 0 2 2 2 1 Subtilase family FNIP PF05725.12 EGC30882.1 - 1.7e-123 402.6 60.4 1.8e-16 60.0 0.4 11.6 6 3 8 14 14 14 14 FNIP Repeat DUF3215 PF11503.8 EGC30882.1 - 0.055 13.3 1.0 24 4.8 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3215) Band_3_cyto PF07565.13 EGC30883.1 - 0.082 12.7 7.0 1.8 8.3 3.4 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain EPL1 PF10513.9 EGC30883.1 - 0.097 13.1 7.2 0.18 12.2 7.2 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3408 PF11888.8 EGC30883.1 - 0.19 11.9 9.3 6.7 6.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Prefoldin PF02996.17 EGC30884.1 - 5.2e-19 68.3 3.9 5.2e-19 68.3 3.9 1.6 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.20 EGC30884.1 - 0.00052 19.9 3.8 0.00052 19.9 3.8 2.6 1 1 2 3 3 3 1 Prefoldin subunit DUF4988 PF16378.5 EGC30884.1 - 1.9 8.2 5.8 2.4 7.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function GIT_CC PF16559.5 EGC30884.1 - 2.3 8.1 10.4 0.84 9.6 0.2 2.7 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor KxDL PF10241.9 EGC30884.1 - 3.5 8.0 8.3 0.92 9.8 0.3 2.9 2 1 2 4 4 4 0 Uncharacterized conserved protein LysM PF01476.20 EGC30885.1 - 0.00031 20.8 0.1 0.0019 18.2 0.0 2.3 2 0 0 2 2 2 1 LysM domain ARD PF03079.14 EGC30885.1 - 0.85 9.8 5.4 0.79 9.9 1.4 2.1 2 0 0 2 2 2 0 ARD/ARD' family Ribosomal_60s PF00428.19 EGC30887.1 - 2.1e-26 92.3 15.1 4.7e-26 91.2 15.1 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein DUF3015 PF11220.8 EGC30888.1 - 0.085 12.7 0.0 0.2 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Rhomboid PF01694.22 EGC30889.1 - 1.6e-25 89.9 10.1 3.3e-25 88.8 10.1 1.4 1 0 0 1 1 1 1 Rhomboid family Zn-C2H2_12 PF18112.1 EGC30890.1 - 0.021 15.3 0.6 0.073 13.5 0.6 2.1 1 0 0 1 1 1 0 Autophagy receptor zinc finger-C2H2 domain DRY_EERY PF09750.9 EGC30890.1 - 0.26 11.6 5.5 1.2 9.4 5.5 2.2 1 0 0 1 1 1 0 Alternative splicing regulator DUF3439 PF11921.8 EGC30890.1 - 4.2 7.4 11.2 0.73 9.8 7.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) His_Phos_2 PF00328.22 EGC30892.1 - 4.3e-23 82.3 0.0 6.1e-23 81.8 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Med6 PF04934.14 EGC30892.1 - 0.033 14.0 0.2 0.059 13.2 0.2 1.5 1 1 0 1 1 1 0 MED6 mediator sub complex component Cyclin_N PF00134.23 EGC30893.1 - 0.021 14.6 0.2 0.038 13.7 0.2 1.5 1 0 0 1 1 1 0 Cyclin, N-terminal domain PH_TFIIH PF08567.11 EGC30894.1 - 1.4e-14 54.2 0.2 4.6e-14 52.5 0.2 2.0 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain BSD PF03909.17 EGC30894.1 - 1.3e-13 50.7 3.7 2.6e-11 43.3 0.4 3.9 5 0 0 5 5 5 2 BSD domain Vps36_ESCRT-II PF11605.8 EGC30894.1 - 0.082 13.1 2.4 0.12 12.6 0.1 2.5 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 EMP70 PF02990.16 EGC30895.1 - 1.5e-204 680.5 8.7 2.2e-204 679.9 8.7 1.3 1 0 0 1 1 1 1 Endomembrane protein 70 Internalin_N PF12354.8 EGC30895.1 - 0.35 11.0 0.1 0.35 11.0 0.1 3.0 4 0 0 4 4 4 0 Bacterial adhesion/invasion protein N terminal Abhydrolase_1 PF00561.20 EGC30896.1 - 1.1e-07 31.8 0.0 1.7e-07 31.2 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold RR_TM4-6 PF06459.12 EGC30896.1 - 0.0093 15.8 6.8 0.016 15.0 6.8 1.5 1 0 0 1 1 1 1 Ryanodine Receptor TM 4-6 Zip PF02535.22 EGC30896.1 - 0.052 12.8 19.4 0.45 9.7 1.4 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter CDC45 PF02724.14 EGC30896.1 - 0.097 11.0 4.4 0.15 10.3 4.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4114 PF13448.6 EGC30896.1 - 0.13 13.1 0.1 0.13 13.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4114) Tim54 PF11711.8 EGC30896.1 - 0.39 9.4 6.6 0.63 8.8 6.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RNA_pol_Rpc4 PF05132.14 EGC30896.1 - 0.42 11.0 7.9 0.93 9.9 7.9 1.5 1 0 0 1 1 1 0 RNA polymerase III RPC4 Presenilin PF01080.17 EGC30896.1 - 0.49 9.1 3.5 0.94 8.2 3.5 1.5 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EGC30896.1 - 1.5 8.6 13.4 2.6 7.8 13.4 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Sec62 PF03839.16 EGC30896.1 - 1.7 8.1 9.7 3.6 7.0 9.7 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Connexin PF00029.19 EGC30896.1 - 9.1 6.0 10.6 0.78 9.5 5.8 1.6 2 0 0 2 2 2 0 Connexin Transket_pyr PF02779.24 EGC30897.1 - 8.6e-46 155.8 0.0 1.2e-45 155.3 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.20 EGC30897.1 - 6.7e-38 129.4 0.0 1.1e-37 128.6 0.0 1.4 1 0 0 1 1 1 1 Transketolase, C-terminal domain ssDBP PF17878.1 EGC30897.1 - 0.15 12.3 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 Single-stranded DNA-binding protein DUF656 PF04920.12 EGC30898.1 - 0.027 14.4 0.5 0.082 12.8 0.2 1.9 2 0 0 2 2 2 0 Family of unknown function (DUF656) Transpos_assoc PF13963.6 EGC30898.1 - 0.092 13.1 0.1 0.24 11.8 0.1 1.7 1 0 0 1 1 1 0 Transposase-associated domain DUF4767 PF15983.5 EGC30899.1 - 0.016 15.5 0.1 0.017 15.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4767) PARP PF00644.20 EGC30900.1 - 1.9e-33 115.7 1.4 5.4e-28 97.9 0.0 2.7 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC30900.1 - 2.6e-15 56.7 6.8 2.6e-15 56.7 6.8 2.3 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT PF00533.26 EGC30900.1 - 7e-07 29.5 1.2 3.3e-06 27.4 0.7 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC30900.1 - 0.00049 20.4 0.7 0.0027 18.1 0.7 2.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 EGC30900.1 - 0.0012 18.9 0.3 0.0032 17.5 0.3 1.7 1 0 0 1 1 1 1 WGR domain Response_reg PF00072.24 EGC30901.1 - 2.4e-22 79.2 0.1 4.1e-22 78.5 0.1 1.4 1 0 0 1 1 1 1 Response regulator receiver domain EamA PF00892.20 EGC30903.1 - 9.9e-07 29.0 11.4 3.7e-06 27.2 11.4 1.8 1 1 0 1 1 1 1 EamA-like transporter family TMEM234 PF10639.9 EGC30903.1 - 0.0075 16.3 0.2 0.0075 16.3 0.2 2.3 1 1 0 2 2 2 1 Putative transmembrane family 234 UAA PF08449.11 EGC30903.1 - 0.24 10.6 7.4 0.33 10.1 7.4 1.3 1 1 0 1 1 1 0 UAA transporter family Multi_Drug_Res PF00893.19 EGC30903.1 - 0.26 12.0 5.0 0.51 11.0 4.8 1.6 1 1 0 1 1 1 0 Small Multidrug Resistance protein DUF543 PF04418.12 EGC30903.1 - 0.41 10.6 2.7 6.6 6.8 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Hist_deacetyl PF00850.19 EGC30904.1 - 7.1e-82 275.3 0.8 7.6e-82 275.2 0.1 1.4 2 0 0 2 2 2 1 Histone deacetylase domain FNIP PF05725.12 EGC30905.1 - 2.4e-16 59.6 30.6 8.2e-07 29.1 0.6 5.5 5 1 1 6 6 6 4 FNIP Repeat Zip PF02535.22 EGC30905.1 - 7.6e-09 35.2 1.7 1.1e-08 34.7 1.7 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter zf-B_box PF00643.24 EGC30905.1 - 2e-05 24.6 6.1 3.5e-05 23.9 6.1 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC30905.1 - 0.051 13.7 2.6 0.1 12.8 2.6 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LigB PF02900.18 EGC30905.1 - 0.2 10.7 0.2 7.5 5.5 0.0 2.8 1 1 2 3 3 3 0 Catalytic LigB subunit of aromatic ring-opening dioxygenase DUF1644 PF07800.12 EGC30905.1 - 3.6 7.6 5.4 10 6.2 5.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) FNIP PF05725.12 EGC30906.1 - 8.4e-17 61.1 16.6 0.00033 20.7 0.1 5.8 4 1 0 5 5 5 4 FNIP Repeat zf-B_box PF00643.24 EGC30906.1 - 7e-05 22.9 4.4 0.00012 22.1 4.4 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC30906.1 - 0.16 12.1 1.5 0.32 11.2 1.5 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Mcm10 PF09332.11 EGC30906.1 - 1.9 7.8 5.7 2.7 7.4 5.7 1.1 1 0 0 1 1 1 0 Mcm10 replication factor Zip PF02535.22 EGC30907.1 - 9.3e-37 127.0 11.2 1.1e-36 126.7 11.2 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TMEM214 PF10151.9 EGC30907.1 - 0.06 11.8 0.3 0.098 11.1 0.1 1.3 2 0 0 2 2 2 0 TMEM214, C-terminal, caspase 4 activator Mntp PF02659.15 EGC30907.1 - 0.067 12.9 0.3 0.067 12.9 0.3 3.1 2 1 1 3 3 3 0 Putative manganese efflux pump FNIP PF05725.12 EGC30908.1 - 1.6e-10 41.0 19.9 1.3e-05 25.3 0.6 3.7 1 1 3 4 4 4 4 FNIP Repeat Mucin PF01456.17 EGC30909.1 - 0.18 11.8 15.4 0.28 11.2 15.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein End3 PF12761.7 EGC30909.1 - 0.82 9.8 12.9 0.2 11.8 5.2 2.2 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 WBP-1 PF11669.8 EGC30909.1 - 1.7 9.3 4.8 3.7 8.2 4.4 1.7 1 1 0 1 1 1 0 WW domain-binding protein 1 SWIB PF02201.18 EGC30910.1 - 8.7e-19 67.2 0.6 1.7e-18 66.3 0.6 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DOT1 PF08123.13 EGC30910.1 - 0.00058 19.5 0.4 0.0012 18.4 0.1 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 GidB PF02527.15 EGC30910.1 - 0.072 12.4 0.8 0.41 9.9 0.1 2.3 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G RGS PF00615.19 EGC30910.1 - 0.27 11.5 4.7 1.4 9.2 0.4 2.5 2 0 0 2 2 2 0 Regulator of G protein signaling domain ketoacyl-synt PF00109.26 EGC30911.1 - 1.3e-63 214.9 0.0 2.1e-63 214.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC30911.1 - 2e-43 148.4 0.0 4.3e-43 147.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC30911.1 - 4.2e-36 125.1 0.0 9.9e-36 123.8 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC30911.1 - 2.6e-30 104.9 0.0 2.5e-29 101.7 0.0 2.5 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC30911.1 - 1.4e-26 93.6 0.0 3.5e-25 89.0 0.1 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC30911.1 - 6.1e-21 74.9 0.0 9.6e-21 74.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC30911.1 - 1.9e-16 60.6 2.2 1.8e-15 57.5 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC30911.1 - 6.6e-15 55.5 0.1 2.1e-14 53.9 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC30911.1 - 2.1e-09 38.5 0.0 8.8e-09 36.5 0.0 2.1 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC30911.1 - 1.1e-07 31.5 0.0 4.2e-05 23.1 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_N PF08240.12 EGC30911.1 - 2.6e-06 27.3 0.0 6.1e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC30911.1 - 3.6e-06 26.9 0.0 1e-05 25.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EGC30911.1 - 1.5e-05 24.5 1.1 0.12 11.7 0.0 2.8 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase PP-binding PF00550.25 EGC30911.1 - 8.2e-05 22.9 0.1 0.0002 21.6 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGC30911.1 - 0.00013 22.5 0.0 0.00047 20.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC30911.1 - 0.00019 20.9 0.0 0.00042 19.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EGC30911.1 - 0.00036 20.4 0.6 0.053 13.3 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGC30911.1 - 0.00042 20.1 0.4 0.0011 18.7 0.0 1.9 2 0 0 2 2 1 1 Lysine methyltransferase 23S_rRNA_IVP PF05635.11 EGC30911.1 - 0.0073 16.6 1.0 0.048 13.9 0.5 2.8 2 0 0 2 2 2 1 23S rRNA-intervening sequence protein DUF1430 PF07242.11 EGC30911.1 - 0.041 14.2 0.4 0.26 11.6 0.4 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) adh_short PF00106.25 EGC30911.1 - 0.078 12.4 0.3 0.21 11.0 0.3 1.8 1 0 0 1 1 1 0 short chain dehydrogenase ketoacyl-synt PF00109.26 EGC30912.1 - 1.9e-62 211.1 0.0 3.2e-62 210.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC30912.1 - 7.7e-41 139.9 0.0 1.8e-40 138.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC30912.1 - 1.4e-38 133.2 0.0 3.2e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC30912.1 - 5.7e-31 107.0 0.0 2.4e-30 104.9 0.0 2.1 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC30912.1 - 7.9e-27 94.3 0.1 1.3e-25 90.3 0.1 2.4 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC30912.1 - 2.2e-22 79.6 0.0 3.5e-22 79.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC30912.1 - 1.7e-16 60.7 2.4 2.5e-15 57.0 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC30912.1 - 1.1e-15 58.0 0.1 3.5e-15 56.4 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC30912.1 - 1.2e-09 39.4 0.0 8.8e-09 36.5 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC30912.1 - 5e-07 29.4 0.1 0.00028 20.4 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.6 EGC30912.1 - 2.8e-06 27.3 0.0 8e-06 25.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EGC30912.1 - 3.1e-06 27.0 0.0 7.5e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_25 PF13649.6 EGC30912.1 - 4.4e-05 24.1 0.0 0.00012 22.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC30912.1 - 5.2e-05 23.1 0.4 0.01 15.6 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGC30912.1 - 8.7e-05 22.8 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC30912.1 - 0.00012 21.5 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EGC30912.1 - 0.00014 21.4 1.3 0.2 11.0 0.2 3.3 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase Methyltransf_11 PF08241.12 EGC30912.1 - 0.00046 20.8 0.0 0.0015 19.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGC30912.1 - 0.00079 19.2 0.0 0.0029 17.4 0.0 1.9 1 0 0 1 1 1 1 Lysine methyltransferase 23S_rRNA_IVP PF05635.11 EGC30912.1 - 0.0083 16.4 0.9 0.076 13.3 0.4 3.1 2 0 0 2 2 2 1 23S rRNA-intervening sequence protein DUF1430 PF07242.11 EGC30912.1 - 0.043 14.1 0.4 0.3 11.4 0.4 2.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) NodS PF05401.11 EGC30912.1 - 0.11 12.1 0.0 0.24 11.0 0.0 1.5 1 0 0 1 1 1 0 Nodulation protein S (NodS) Pkinase PF00069.25 EGC30913.1 - 9.2e-78 261.2 0.0 1.4e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30913.1 - 2e-33 115.8 0.0 1.1e-32 113.4 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC30913.1 - 3e-06 26.4 1.0 4.4e-06 25.9 1.0 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC30913.1 - 0.0097 15.2 0.0 0.71 9.1 0.0 2.2 2 0 0 2 2 2 2 Kinase-like MMR_HSR1_C PF08438.10 EGC30914.1 - 0.017 15.7 1.8 0.065 13.8 1.8 2.0 1 0 0 1 1 1 0 GTPase of unknown function C-terminal EF-hand_6 PF13405.6 EGC30914.1 - 0.046 13.7 0.0 0.35 10.9 0.0 2.6 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EGC30914.1 - 0.12 12.0 1.8 1.9 8.3 0.0 3.6 4 0 0 4 4 4 0 EF hand EF-hand_7 PF13499.6 EGC30914.1 - 0.87 10.1 10.0 2 8.9 1.3 3.9 4 1 0 4 4 4 0 EF-hand domain pair RNA_pol_3_Rpc31 PF11705.8 EGC30915.1 - 0.002 18.4 14.8 0.002 18.4 14.8 4.7 3 1 1 4 4 4 2 DNA-directed RNA polymerase III subunit Rpc31 WD40 PF00400.32 EGC30916.1 - 2.4e-26 91.5 20.9 3.5e-06 27.6 0.3 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGC30916.1 - 5.6e-08 32.8 4.6 0.00018 21.5 0.2 5.4 3 2 3 6 6 6 2 Ciliary BBSome complex subunit 2, middle region F-box PF00646.33 EGC30916.1 - 0.002 17.9 0.7 0.35 10.8 0.0 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.7 EGC30916.1 - 0.011 15.6 0.0 0.023 14.6 0.0 1.6 1 0 0 1 1 1 0 F-box-like F-box-like_2 PF13013.6 EGC30916.1 - 0.02 14.8 0.3 0.23 11.4 0.3 2.4 1 1 0 1 1 1 0 F-box-like domain Bap31 PF05529.12 EGC30917.1 - 2.3e-17 63.1 1.9 2.3e-17 63.1 1.9 1.8 2 0 0 2 2 2 1 Bap31/Bap29 transmembrane region Bap31_Bap29_C PF18035.1 EGC30917.1 - 8.5e-06 25.7 18.9 8.5e-06 25.7 18.9 2.1 2 0 0 2 2 2 1 Bap31/Bap29 cytoplasmic coiled-coil domain Vac17 PF17321.2 EGC30917.1 - 0.0011 18.5 10.1 0.0013 18.3 10.1 1.1 1 0 0 1 1 1 1 Vacuole-related protein 17 YabA PF06156.13 EGC30917.1 - 0.0089 16.6 10.7 0.019 15.6 10.7 1.5 1 0 0 1 1 1 1 Initiation control protein YabA CSG2 PF16965.5 EGC30917.1 - 0.093 11.7 3.9 0.11 11.4 3.8 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HALZ PF02183.18 EGC30917.1 - 0.1 12.9 11.7 0.1 12.8 2.8 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper DUF3450 PF11932.8 EGC30917.1 - 0.1 11.9 9.7 0.16 11.2 9.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.11 EGC30917.1 - 0.27 11.0 17.3 0.46 10.3 17.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 UPF0242 PF06785.11 EGC30917.1 - 0.31 11.1 16.3 0.46 10.6 16.3 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus bZIP_1 PF00170.21 EGC30917.1 - 0.41 10.8 13.0 1.5 9.0 4.4 2.6 1 1 1 2 2 2 0 bZIP transcription factor Jnk-SapK_ap_N PF09744.9 EGC30917.1 - 0.45 10.7 13.8 0.77 10.0 13.8 1.3 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 Speriolin_N PF15058.6 EGC30917.1 - 0.66 10.0 2.9 0.93 9.5 2.9 1.2 1 0 0 1 1 1 0 Speriolin N terminus Sec34 PF04136.15 EGC30917.1 - 0.89 9.4 13.5 0.18 11.7 3.3 2.5 2 1 1 3 3 3 0 Sec34-like family DivIC PF04977.15 EGC30917.1 - 1.9 8.3 16.4 1.8 8.4 4.5 3.3 2 1 1 3 3 3 0 Septum formation initiator FapA PF03961.13 EGC30917.1 - 2.6 6.6 13.1 3.3 6.2 13.1 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A PCRF PF03462.18 EGC30917.1 - 3.8 7.3 13.7 2.3 8.0 11.9 1.4 2 0 0 2 2 2 0 PCRF domain Spc24 PF08286.11 EGC30917.1 - 8.8 6.6 14.8 93 3.3 14.8 2.2 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 DUF3430 PF11912.8 EGC30918.1 - 0.0017 18.4 9.5 0.0028 17.7 9.5 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Tnp_P_element_C PF12596.8 EGC30918.1 - 0.16 12.6 0.0 1 9.9 0.0 2.0 2 0 0 2 2 2 0 87kDa Transposase TatD_DNase PF01026.21 EGC30919.1 - 4.2e-45 154.1 0.1 7.9e-45 153.2 0.0 1.5 2 0 0 2 2 2 1 TatD related DNase DUF2183 PF09949.9 EGC30919.1 - 0.002 18.4 1.1 0.44 10.9 0.0 3.8 3 1 0 3 3 3 1 Uncharacterized conserved protein (DUF2183) zinc_ribbon_10 PF10058.9 EGC30919.1 - 0.016 15.0 1.3 5.6 6.8 0.1 2.7 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein ANAPC_CDC26 PF10471.9 EGC30919.1 - 0.048 14.5 2.3 0.048 14.5 2.3 4.4 3 1 1 4 4 4 0 Anaphase-promoting complex APC subunit CDC26 Amidohydro_2 PF04909.14 EGC30919.1 - 0.2 11.4 0.0 1 9.1 0.0 2.0 2 0 0 2 2 2 0 Amidohydrolase M_domain PF12938.7 EGC30919.1 - 0.25 11.1 9.0 0.067 13.0 5.4 1.8 2 0 0 2 2 2 0 M domain of GW182 DUF2757 PF10955.8 EGC30919.1 - 0.41 10.9 6.7 3.9 7.8 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2757) DZR PF12773.7 EGC30919.1 - 0.51 10.4 3.4 6.2 6.9 1.7 2.4 2 0 0 2 2 2 0 Double zinc ribbon BUD22 PF09073.10 EGC30919.1 - 1.1 8.5 46.3 0.049 13.0 28.5 2.2 2 0 0 2 2 2 0 BUD22 PT PF04886.12 EGC30920.1 - 0.0067 16.0 49.1 0.031 13.8 46.5 2.4 2 1 0 2 2 2 1 PT repeat Trypan_PARP PF05887.11 EGC30920.1 - 0.048 13.6 17.7 0.089 12.8 17.7 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4106 PF13388.6 EGC30920.1 - 0.12 11.5 8.1 0.19 11.0 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) CDtoxinA PF03498.14 EGC30920.1 - 0.14 11.7 3.0 0.14 11.7 0.0 2.5 3 0 0 3 3 3 0 Cytolethal distending toxin A/C domain TPR_12 PF13424.6 EGC30921.1 - 1.2e-33 115.2 16.7 4.6e-11 42.9 1.3 4.5 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_10 PF13374.6 EGC30921.1 - 8.9e-16 57.2 2.7 0.034 14.0 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat DUF4062 PF13271.6 EGC30921.1 - 2.6e-15 56.6 1.8 5.8e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) NACHT PF05729.12 EGC30921.1 - 7e-12 45.6 0.0 7e-12 45.6 0.0 2.2 2 0 0 2 2 1 1 NACHT domain TPR_2 PF07719.17 EGC30921.1 - 3.3e-08 33.1 10.8 0.24 11.6 0.3 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC30921.1 - 7.6e-08 32.1 0.4 7.6e-08 32.1 0.4 2.8 2 1 0 2 2 1 1 MalT-like TPR region TIG PF01833.24 EGC30921.1 - 8.6e-08 32.2 1.1 2.4e-07 30.7 1.1 1.8 1 0 0 1 1 1 1 IPT/TIG domain TPR_7 PF13176.6 EGC30921.1 - 9.7e-06 25.3 3.1 1.5 9.0 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC30921.1 - 9.9e-06 25.2 13.9 0.34 10.8 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat AAA_16 PF13191.6 EGC30921.1 - 1.5e-05 25.5 2.4 2.5e-05 24.7 0.0 2.5 2 0 0 2 2 1 1 AAA ATPase domain TPR_8 PF13181.6 EGC30921.1 - 0.00036 20.5 17.8 0.075 13.3 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC30921.1 - 0.0013 19.4 0.2 27 5.9 0.0 5.4 3 2 3 6 6 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGC30921.1 - 0.0023 18.2 1.0 0.01 16.1 0.0 2.7 2 1 1 3 3 2 1 AAA domain RsgA_GTPase PF03193.16 EGC30921.1 - 0.0035 17.3 0.5 0.014 15.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 EGC30921.1 - 0.0078 15.4 0.0 0.0078 15.4 0.0 2.5 2 1 1 3 3 2 1 NB-ARC domain ATPase_2 PF01637.18 EGC30921.1 - 0.011 15.6 0.1 0.011 15.6 0.1 3.5 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea SNAP PF14938.6 EGC30921.1 - 0.02 14.3 7.6 0.23 10.9 3.1 2.6 1 1 0 2 2 2 0 Soluble NSF attachment protein, SNAP BRCT PF00533.26 EGC30921.1 - 0.052 13.9 0.8 0.23 11.9 0.8 2.2 1 0 0 1 1 1 0 BRCA1 C Terminus (BRCT) domain AAA_29 PF13555.6 EGC30921.1 - 0.17 11.7 0.0 0.39 10.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MRP PF09387.10 EGC30921.1 - 0.18 11.8 0.0 0.18 11.8 0.0 1.8 2 0 0 2 2 1 0 Mitochondrial RNA binding protein MRP DUF627 PF04781.12 EGC30921.1 - 0.18 11.8 1.7 2.1 8.4 0.1 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF627) TPR_16 PF13432.6 EGC30921.1 - 0.67 10.6 1.6 82 4.0 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGC30921.1 - 9.8 6.7 8.2 12 6.5 0.0 3.6 3 0 0 3 3 3 0 ABC transporter LMBR1 PF04791.16 EGC30922.1 - 4.5e-20 72.1 27.4 8.9e-20 71.1 3.3 2.7 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF2628 PF10947.8 EGC30922.1 - 1.9 8.9 0.0 1.9 8.9 0.0 4.0 5 2 0 5 5 5 0 Protein of unknown function (DUF2628) DUF2207 PF09972.9 EGC30922.1 - 4.5 5.9 27.1 2.2 7.0 9.8 4.0 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) TMEM164 PF14808.6 EGC30923.1 - 2e-21 76.5 14.2 2.5e-21 76.2 14.2 1.1 1 0 0 1 1 1 1 TMEM164 family Methyltrans_RNA PF04452.14 EGC30925.1 - 1.4e-41 142.3 1.0 6.8e-41 140.1 1.0 1.9 1 1 0 1 1 1 1 RNA methyltransferase WD40 PF00400.32 EGC30928.1 - 7.3e-29 99.4 17.6 6.9e-06 26.7 0.2 7.3 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30928.1 - 3e-17 62.7 3.5 3.1e-07 30.6 0.2 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC30928.1 - 1.3e-08 34.9 4.2 0.1 12.5 0.0 4.2 4 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGC30928.1 - 4.3e-05 22.6 1.1 0.15 11.0 0.0 3.8 3 2 1 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF4073 PF13285.6 EGC30928.1 - 0.026 14.2 1.7 0.053 13.2 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4073) ATG_C PF09333.11 EGC30930.1 - 8e-34 115.9 0.2 8e-34 115.9 0.2 2.3 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGC30930.1 - 1.8e-10 40.9 0.1 1.8e-10 40.9 0.1 3.2 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 ATG2_CAD PF13329.6 EGC30930.1 - 2.3e-09 37.2 3.1 2.5e-09 37.0 0.1 2.8 2 0 0 2 2 2 1 Autophagy-related protein 2 CAD motif DUF4446 PF14584.6 EGC30931.1 - 0.0069 16.4 3.2 0.017 15.1 3.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF4446) ABC2_membrane_2 PF12679.7 EGC30931.1 - 0.036 13.3 0.0 0.037 13.3 0.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TFIIA PF03153.13 EGC30931.1 - 0.041 13.9 19.6 0.061 13.3 19.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Virul_fac_BrkB PF03631.15 EGC30931.1 - 0.076 12.6 0.4 0.11 12.1 0.4 1.2 1 0 0 1 1 1 0 Virulence factor BrkB Tetraspanin PF00335.20 EGC30931.1 - 0.081 12.6 0.0 0.093 12.4 0.0 1.3 1 1 0 1 1 1 0 Tetraspanin family HSV_VP16_C PF12149.8 EGC30931.1 - 0.16 12.1 0.2 0.33 11.1 0.2 1.5 1 0 0 1 1 1 0 Herpes simplex virus virion protein 16 C terminal Ndc1_Nup PF09531.10 EGC30931.1 - 0.53 8.9 7.8 0.61 8.7 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SDP_N PF12278.8 EGC30931.1 - 0.57 10.3 8.2 1.7 8.7 8.2 1.9 1 0 0 1 1 1 0 Sex determination protein N terminal Neur_chan_memb PF02932.16 EGC30931.1 - 1.7 8.6 9.0 2.2 8.3 9.0 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1635 PF07795.11 EGC30931.1 - 5.7 6.7 23.5 0.059 13.2 11.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1635) Ezh2_MCSS PF18600.1 EGC30932.1 - 0.12 12.0 0.8 0.35 10.5 0.2 2.1 2 1 0 2 2 2 0 MCSS domain Coiled PF05710.12 EGC30935.1 - 0.16 12.8 15.6 0.47 11.3 15.6 1.7 1 1 0 1 1 1 0 Coiled coil ACOX PF01756.19 EGC30937.1 - 0.083 12.4 1.0 0.082 12.5 0.2 1.4 2 0 0 2 2 2 0 Acyl-CoA oxidase BRCT PF00533.26 EGC30938.1 - 3.5e-11 43.3 3.9 6.8e-11 42.4 2.1 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC30938.1 - 1.9e-08 34.6 2.0 4.1e-08 33.5 0.8 2.2 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain VP4_helical PF17478.2 EGC30938.1 - 0.015 14.8 1.8 0.015 14.8 1.8 1.9 3 0 0 3 3 3 0 Rotavirus VP4 helical domain PTCB-BRCT PF12738.7 EGC30938.1 - 0.021 14.8 0.1 0.048 13.6 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain U62_UL91 PF17442.2 EGC30938.1 - 0.036 14.1 0.2 0.099 12.6 0.2 1.8 1 0 0 1 1 1 0 Functional domain of U62 and UL91 proteins RTT107_BRCT_5 PF16770.5 EGC30938.1 - 4.8 7.1 9.2 0.081 12.8 0.9 2.4 3 0 0 3 3 3 0 Regulator of Ty1 transposition protein 107 BRCT domain AbfS_sensor PF18225.1 EGC30939.1 - 0.054 13.4 0.1 0.061 13.2 0.1 1.3 1 0 0 1 1 1 0 Sensor histidine kinase (AbfS) sensor domain Orf78 PF06024.12 EGC30941.1 - 0.31 11.4 5.6 0.5 10.7 5.6 1.3 1 0 0 1 1 1 0 Orf78 (ac78) HCO3_cotransp PF00955.21 EGC30941.1 - 1.3 7.7 4.2 1.6 7.5 4.2 1.0 1 0 0 1 1 1 0 HCO3- transporter family FNIP PF05725.12 EGC30942.1 - 4.5e-150 487.6 82.1 8.4e-15 54.7 1.6 11.4 4 2 7 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.13 EGC30942.1 - 0.00072 19.9 0.0 21 5.5 0.0 5.5 4 2 2 6 6 6 1 Phage minor tail protein Peptidase_C21 PF05381.12 EGC30942.1 - 0.1 13.0 12.1 3.9 7.9 0.4 5.2 1 1 2 5 5 5 0 Tymovirus endopeptidase DUF11 PF01345.18 EGC30942.1 - 1.6 9.0 8.4 48 4.3 0.1 4.8 2 1 3 5 5 5 0 Domain of unknown function DUF11 Tyr-DNA_phospho PF06087.12 EGC30943.1 - 9.6e-49 166.4 16.0 2.1e-33 115.9 10.9 2.2 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Uteroglobin PF01099.17 EGC30943.1 - 0.63 10.4 1.9 1.7 9.0 1.9 1.8 1 0 0 1 1 1 0 Uteroglobin family Exo_endo_phos PF03372.23 EGC30945.1 - 2.8e-19 69.6 0.0 7.8e-19 68.1 0.0 1.7 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ras PF00071.22 EGC30946.1 - 1.2e-28 99.8 1.0 4.4e-28 97.9 1.0 1.8 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC30946.1 - 6e-11 42.6 0.4 1.8e-10 41.1 0.1 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30946.1 - 7.8e-11 41.7 0.6 1.9e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Vasculin PF15337.6 EGC30946.1 - 0.16 12.8 1.3 0.33 11.8 1.3 1.5 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 FNIP PF05725.12 EGC30947.1 - 1.7e-95 312.9 63.1 8.5e-13 48.2 0.2 11.5 8 3 3 12 12 12 11 FNIP Repeat LRR_5 PF13306.6 EGC30947.1 - 0.041 13.8 1.1 5.9 6.9 0.5 3.2 2 2 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Pkinase_Tyr PF07714.17 EGC30948.1 - 1.2e-60 205.0 0.0 1.5e-60 204.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC30948.1 - 1.4e-57 195.0 0.0 2.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Mucin PF01456.17 EGC30948.1 - 0.002 18.1 26.1 0.002 18.1 26.1 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein APH PF01636.23 EGC30948.1 - 0.0024 17.8 0.1 0.0062 16.5 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family SPX PF03105.19 EGC30948.1 - 0.0059 16.6 6.5 0.011 15.7 6.5 1.5 1 0 0 1 1 1 1 SPX domain Haspin_kinase PF12330.8 EGC30948.1 - 0.02 13.8 0.6 0.19 10.7 0.0 2.5 3 0 0 3 3 3 0 Haspin like kinase domain PRIMA1 PF16101.5 EGC30948.1 - 0.043 13.9 7.0 0.024 14.7 3.5 2.5 2 0 0 2 2 2 0 Proline-rich membrane anchor 1 DUF3290 PF11694.8 EGC30948.1 - 0.058 13.4 2.0 0.15 12.0 2.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) DUF3139 PF11337.8 EGC30948.1 - 0.073 13.7 5.8 2.7 8.7 1.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Pkinase_fungal PF17667.1 EGC30948.1 - 0.078 11.7 1.2 0.23 10.2 0.0 1.9 2 0 0 2 2 2 0 Fungal protein kinase TMEM154 PF15102.6 EGC30948.1 - 0.1 12.5 0.0 0.1 12.5 0.0 4.0 2 1 1 3 3 2 0 TMEM154 protein family Macoilin PF09726.9 EGC30948.1 - 0.39 9.2 17.4 0.58 8.6 17.4 1.1 1 0 0 1 1 1 0 Macoilin family Sigma_reg_N PF13800.6 EGC30948.1 - 2.1 8.7 8.5 1.3 9.4 2.6 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal ATP1G1_PLM_MAT8 PF02038.16 EGC30948.1 - 4.8 6.7 5.2 0.43 10.1 0.2 1.8 2 0 0 2 2 1 0 ATP1G1/PLM/MAT8 family ATP-synt_8 PF00895.20 EGC30948.1 - 8.9 6.9 9.1 3.2 8.3 4.1 2.8 2 0 0 2 2 2 0 ATP synthase protein 8 NTP_transf_2 PF01909.23 EGC30949.1 - 8.5e-07 29.2 0.2 4.8e-06 26.8 0.2 2.3 1 0 0 1 1 1 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 EGC30949.1 - 0.0012 19.0 0.0 0.0034 17.6 0.0 1.8 1 0 0 1 1 1 1 tRNA nucleotidyltransferase, second domain MRP-L27 PF09809.9 EGC30949.1 - 0.0049 16.7 0.8 0.014 15.2 0.2 2.0 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 OAS1_C PF10421.9 EGC30949.1 - 0.011 15.3 0.5 0.022 14.3 0.1 1.7 2 0 0 2 2 2 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Polbeta PF18765.1 EGC30949.1 - 0.017 15.2 3.0 0.026 14.6 0.3 2.8 3 0 0 3 3 3 0 Polymerase beta, Nucleotidyltransferase PAP_assoc PF03828.19 EGC30949.1 - 0.022 14.9 0.3 0.061 13.5 0.3 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase VIT1 PF01988.19 EGC30950.1 - 2.1e-47 161.8 0.2 2.4e-47 161.6 0.2 1.0 1 0 0 1 1 1 1 VIT family YqbF PF14553.6 EGC30950.1 - 0.084 12.8 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain DUF1449 PF07290.11 EGC30950.1 - 3.5 7.2 6.7 1.7 8.3 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1449) RasGEF PF00617.19 EGC30951.1 - 5.1e-48 163.6 0.8 5.1e-48 163.6 0.8 1.8 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.27 EGC30951.1 - 8.7e-12 45.1 4.9 1.9e-11 44.0 2.4 2.4 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.20 EGC30951.1 - 3.8e-10 39.9 1.7 3.8e-10 39.9 1.7 3.3 2 1 1 3 3 3 1 RasGEF N-terminal motif DUF1938 PF09153.10 EGC30951.1 - 0.041 14.0 0.4 0.31 11.2 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1938) YchF-GTPase_C PF06071.13 EGC30951.1 - 0.068 13.4 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF933) Rsbr_N PF08678.10 EGC30951.1 - 0.14 12.3 0.3 0.14 12.3 0.3 2.9 3 0 0 3 3 3 0 Rsbr N terminal PrmA PF06325.13 EGC30952.1 - 2.4e-10 40.3 0.0 4.1e-10 39.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGC30952.1 - 3e-10 40.6 0.0 9.4e-10 39.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC30952.1 - 4.9e-10 40.0 0.0 1.4e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC30952.1 - 1.5e-06 27.8 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGC30952.1 - 6.2e-06 26.1 0.0 1.7e-05 24.8 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC30952.1 - 1.4e-05 25.7 0.0 4.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EGC30952.1 - 0.0002 21.3 0.0 0.00041 20.3 0.0 1.5 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.6 EGC30952.1 - 0.00021 21.1 0.3 0.0034 17.2 0.1 2.3 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC30952.1 - 0.00031 20.7 0.0 0.00068 19.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGC30952.1 - 0.00065 19.2 0.0 0.0014 18.1 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_9 PF08003.11 EGC30952.1 - 0.0049 15.8 0.0 0.0095 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGC30952.1 - 0.0062 16.7 0.0 0.015 15.4 0.0 1.7 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_24 PF13578.6 EGC30952.1 - 0.017 16.1 0.0 0.043 14.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain CMAS PF02353.20 EGC30952.1 - 0.036 13.4 0.0 0.083 12.2 0.0 1.6 2 0 0 2 2 2 0 Mycolic acid cyclopropane synthetase CaMKII_AD PF08332.10 EGC30952.1 - 0.056 13.6 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II association domain Methyltransf_16 PF10294.9 EGC30952.1 - 0.093 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Lysine methyltransferase Cons_hypoth95 PF03602.15 EGC30952.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_32 PF13679.6 EGC30952.1 - 0.14 12.1 0.1 0.26 11.3 0.1 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ependymin PF00811.18 EGC30953.1 - 0.00035 20.8 0.8 0.00065 20.0 0.8 1.5 1 0 0 1 1 1 1 Ependymin PNK3P PF08645.11 EGC30954.1 - 1.5e-51 174.3 0.0 4.2e-51 172.8 0.0 1.8 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.6 EGC30954.1 - 3.6e-18 66.1 0.1 2.3e-15 57.0 0.1 2.7 1 1 0 1 1 1 1 AAA domain SAP PF02037.27 EGC30954.1 - 9.4e-05 22.1 0.0 0.0002 21.0 0.0 1.6 1 0 0 1 1 1 1 SAP domain KTI12 PF08433.10 EGC30954.1 - 0.0019 17.7 12.0 0.0019 17.7 3.5 2.8 2 1 0 2 2 2 1 Chromatin associated protein KTI12 DUF2052 PF09747.9 EGC30954.1 - 0.028 14.5 12.8 0.043 14.0 12.8 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) CdiA_C PF18451.1 EGC30954.1 - 0.029 14.6 1.5 1.5 9.1 0.5 3.0 2 0 0 2 2 2 0 Contact-dependent growth inhibition CdiA C-terminal domain Hydrolase_6 PF13344.6 EGC30954.1 - 0.11 12.6 0.7 6.4 6.9 0.0 3.3 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Zip PF02535.22 EGC30954.1 - 0.14 11.3 5.9 0.19 10.9 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Nop14 PF04147.12 EGC30954.1 - 0.41 8.8 20.4 0.58 8.3 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family MCM_bind PF09739.9 EGC30954.1 - 2.8 6.3 14.7 4.2 5.7 14.7 1.2 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor DUF913 PF06025.12 EGC30954.1 - 3.3 6.6 8.0 5.2 6.0 8.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGC30954.1 - 5.8 5.6 11.5 7.8 5.1 11.5 1.1 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGC30954.1 - 7.4 5.5 11.1 10 5.0 11.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CPSF100_C PF13299.6 EGC30954.1 - 9.1 6.4 12.3 16 5.6 12.2 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF4061 PF13270.6 EGC30955.1 - 3.2e-16 59.4 2.7 3.2e-16 59.4 2.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4061) DUF2185 PF09951.9 EGC30956.1 - 0.073 12.9 1.7 0.11 12.3 1.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2185) TIG PF01833.24 EGC30957.1 - 1.8e-09 37.5 8.4 9.2e-05 22.4 0.1 3.4 2 1 1 3 3 3 3 IPT/TIG domain PH_15 PF17339.2 EGC30957.1 - 0.035 14.0 0.2 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 PH domain FNIP PF05725.12 EGC30959.1 - 3.3e-55 184.0 57.8 7.3e-09 35.7 0.2 10.5 4 2 8 12 12 12 12 FNIP Repeat CHS5_N PF16892.5 EGC30959.1 - 0.54 10.2 2.8 0.82 9.7 1.0 2.3 2 0 0 2 2 2 0 Chitin biosynthesis protein CHS5 N-terminus Orthopox_F7 PF05813.12 EGC30961.1 - 0.025 14.7 0.2 0.038 14.1 0.2 1.3 1 0 0 1 1 1 0 Orthopoxvirus F7 protein SAM_1 PF00536.30 EGC30962.1 - 0.0013 19.1 0.0 0.0016 18.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC30962.1 - 0.059 13.5 0.0 0.07 13.3 0.0 1.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FNIP PF05725.12 EGC30963.1 - 1.6e-39 133.8 57.5 1.3e-10 41.3 1.6 5.4 1 1 6 7 7 7 7 FNIP Repeat DDE_Tnp_1_7 PF13843.6 EGC30966.1 - 1.4e-21 77.2 0.6 2.3e-21 76.5 0.6 1.4 1 1 0 1 1 1 1 Transposase IS4 YL1 PF05764.13 EGC30966.1 - 0.0093 16.1 10.3 0.016 15.3 10.3 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EGC30966.1 - 0.055 11.7 13.1 0.09 11.0 13.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGC30966.1 - 0.1 12.0 10.3 0.15 11.5 10.3 1.2 1 0 0 1 1 1 0 SDA1 CDC45 PF02724.14 EGC30966.1 - 1.2 7.4 11.0 1.7 6.8 11.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGC30966.1 - 2.7 6.0 5.6 4.1 5.4 5.6 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 EGC30966.1 - 9.7 5.8 9.8 25 4.5 9.8 1.7 1 0 0 1 1 1 0 FAM176 family Pkinase PF00069.25 EGC30968.1 - 3.9e-32 111.7 0.0 5.4e-32 111.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30968.1 - 3.1e-20 72.6 0.0 4e-20 72.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC30968.1 - 1.6e-05 23.9 0.0 1.6e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGC30968.1 - 0.0016 18.4 0.0 0.053 13.4 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family PBP_sp32 PF07222.12 EGC30968.1 - 0.2 11.1 4.1 0.3 10.5 4.1 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Ras PF00071.22 EGC30969.1 - 2e-61 206.3 0.2 2.3e-61 206.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30969.1 - 4.7e-33 113.9 0.1 8.1e-33 113.2 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30969.1 - 4.7e-12 45.7 0.1 5.9e-12 45.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC30969.1 - 8e-05 22.7 0.0 0.00015 21.8 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC30969.1 - 0.00027 20.9 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC30969.1 - 0.0016 18.0 0.1 0.0078 15.8 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGC30969.1 - 0.0076 15.6 0.0 0.0088 15.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.6 EGC30969.1 - 0.074 13.3 0.1 0.38 11.0 0.0 1.9 1 1 0 2 2 2 0 AAA domain DAP3 PF10236.9 EGC30969.1 - 0.076 12.2 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 Ras PF00071.22 EGC30970.1 - 1.3e-37 128.9 0.4 1.6e-37 128.6 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC30970.1 - 4.7e-22 78.5 0.1 7.8e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC30970.1 - 4.6e-08 32.7 0.1 6.8e-08 32.2 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC30970.1 - 2.5e-06 27.6 0.0 3.8e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC30970.1 - 3.8e-05 23.3 0.1 0.0011 18.6 0.1 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_24 PF13479.6 EGC30970.1 - 0.0083 15.9 0.0 0.016 15.0 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC30970.1 - 0.0085 16.5 0.0 0.012 16.0 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain DUF3276 PF11680.8 EGC30970.1 - 0.0088 16.2 0.1 0.21 11.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3276) FeoB_N PF02421.18 EGC30970.1 - 0.015 14.8 0.0 0.59 9.6 0.0 2.5 1 1 0 1 1 1 0 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EGC30970.1 - 0.017 14.5 0.1 0.02 14.2 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region MCM PF00493.23 EGC30970.1 - 0.024 13.8 0.1 0.058 12.5 0.0 1.6 2 0 0 2 2 2 0 MCM P-loop domain SRPRB PF09439.10 EGC30970.1 - 0.026 14.0 0.4 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGC30970.1 - 0.049 14.2 0.0 0.087 13.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter Mg_chelatase PF01078.21 EGC30970.1 - 0.17 11.3 0.0 0.27 10.6 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ALMT PF11744.8 EGC30971.1 - 1.9e-48 165.5 12.2 1.9e-48 165.5 12.2 4.5 3 2 1 4 4 4 2 Aluminium activated malate transporter FUSC_2 PF13515.6 EGC30971.1 - 1.6e-16 60.6 14.9 1.6e-16 60.6 14.9 2.6 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGC30971.1 - 4.8e-11 41.9 3.9 4.8e-11 41.9 3.9 1.6 2 0 0 2 2 2 1 Fusaric acid resistance protein family DUF4404 PF14357.6 EGC30972.1 - 0.016 15.8 1.1 0.036 14.7 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Pet100 PF09803.9 EGC30972.1 - 0.18 12.4 2.5 0.56 10.8 2.5 1.8 1 1 0 1 1 1 0 Pet100 CCDC-167 PF15188.6 EGC30972.1 - 0.62 10.4 8.1 1 9.8 8.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 FAM165 PF14981.6 EGC30972.1 - 3.2 7.6 5.0 23 4.9 0.6 2.5 2 0 0 2 2 2 0 FAM165 family DcpS_C PF11969.8 EGC30974.1 - 1.1e-24 87.1 0.7 1.5e-24 86.7 0.7 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGC30974.1 - 2.5e-11 44.2 0.5 4e-11 43.5 0.5 1.3 1 0 0 1 1 1 1 HIT domain DUF4986 PF16375.5 EGC30974.1 - 0.0014 19.3 0.6 0.0022 18.6 0.6 1.3 1 0 0 1 1 1 1 Domain of unknown function DUF501 PF04417.12 EGC30974.1 - 0.16 11.8 0.0 0.16 11.8 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF501) HAD_SAK_1 PF10307.9 EGC30975.1 - 1.3e-47 162.2 0.9 2.2e-47 161.5 0.9 1.4 1 0 0 1 1 1 1 HAD domain family 1 in Swiss Army Knife RNA repair proteins Pyrophosphatase PF00719.19 EGC30976.1 - 9.2e-42 142.6 1.1 1.1e-41 142.4 1.1 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase Lzipper-MIP1 PF14389.6 EGC30977.1 - 0.028 14.7 1.9 0.62 10.4 1.1 3.1 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 PG_binding_1 PF01471.18 EGC30978.1 - 5.3e-08 32.9 0.0 1.1e-07 31.9 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.14 EGC30978.1 - 0.00025 21.5 0.0 0.00038 20.9 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain CCAP PF11105.8 EGC30979.1 - 0.00029 20.8 0.1 0.00038 20.4 0.1 1.2 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a SNF2_N PF00176.23 EGC30980.1 - 1.5e-52 178.4 0.0 3e-52 177.5 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC30980.1 - 5.9e-15 55.6 0.0 1.7e-14 54.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC30980.1 - 8.2e-07 29.0 0.0 1.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGC30980.1 - 1.2e-05 25.3 4.5 1.3e-05 25.2 0.0 3.0 3 1 1 4 4 4 1 Type III restriction enzyme, res subunit Med13_C PF06333.12 EGC30980.1 - 0.12 11.6 5.5 0.24 10.6 5.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain DUF4667 PF15700.5 EGC30980.1 - 0.18 11.9 14.0 0.052 13.7 6.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4667) WD40 PF00400.32 EGC30981.1 - 2.7e-14 53.3 0.5 0.00013 22.6 0.0 3.8 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC30981.1 - 1e-06 28.9 0.3 0.087 13.1 0.0 3.1 2 2 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC30981.1 - 0.00051 19.1 0.3 0.1 11.5 0.0 2.4 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SBP56 PF05694.11 EGC30981.1 - 0.019 13.8 0.1 0.28 9.9 0.0 2.1 2 0 0 2 2 2 0 56kDa selenium binding protein (SBP56) DUF5065 PF16723.5 EGC30981.1 - 0.029 14.5 2.1 1.5 8.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) Ricin_B_lectin PF00652.22 EGC30981.1 - 0.097 12.9 0.7 0.44 10.8 0.1 2.3 2 1 0 2 2 2 0 Ricin-type beta-trefoil lectin domain Phage_pRha PF09669.10 EGC30981.1 - 0.3 11.7 0.1 0.3 11.7 0.1 2.4 2 1 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) F-box-like PF12937.7 EGC30983.1 - 0.093 12.6 0.2 0.41 10.6 0.0 2.2 2 0 0 2 2 2 0 F-box-like DDE_Tnp_4 PF13359.6 EGC30984.1 - 1.1e-10 41.4 0.0 2e-10 40.6 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.6 EGC30984.1 - 3.2e-05 23.6 0.4 6.6e-05 22.5 0.4 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Med3 PF11593.8 EGC30984.1 - 4.8 6.3 9.5 8.6 5.4 9.5 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Kelch_6 PF13964.6 EGC30985.1 - 3.4e-06 27.1 9.7 0.43 10.9 0.0 5.8 5 1 0 5 5 5 2 Kelch motif Kelch_4 PF13418.6 EGC30985.1 - 0.01 15.8 4.3 1.1 9.3 0.0 4.7 5 0 0 5 5 5 0 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC30985.1 - 0.031 13.9 4.8 3.8 7.2 0.0 4.5 5 0 0 5 5 5 0 Kelch motif Hemopexin PF00045.19 EGC30985.1 - 0.035 14.1 0.4 0.61 10.1 0.0 2.8 3 0 0 3 3 3 0 Hemopexin Coilin_N PF15862.5 EGC30985.1 - 0.28 11.0 8.7 44 3.9 5.4 3.8 4 0 0 4 4 4 0 Coilin N-terminus Pkinase PF00069.25 EGC30986.1 - 7.3e-45 153.4 0.1 3e-29 102.2 0.0 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30986.1 - 2.5e-28 99.1 0.0 1.5e-20 73.6 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC30986.1 - 8.3e-05 21.5 2.7 0.00077 18.3 2.5 2.2 1 1 0 1 1 1 1 Fungal protein kinase PA_decarbox PF05870.11 EGC30986.1 - 0.098 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 Phenolic acid decarboxylase (PAD) Ribosomal_60s PF00428.19 EGC30987.1 - 0.081 13.5 0.0 0.13 12.9 0.0 1.3 1 0 0 1 1 1 0 60s Acidic ribosomal protein Fz PF01392.22 EGC30989.1 - 0.027 15.1 0.2 0.055 14.1 0.0 1.6 2 0 0 2 2 2 0 Fz domain 2-Hacid_dh_C PF02826.19 EGC30990.1 - 1.7e-46 157.8 0.0 3.6e-46 156.7 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC30990.1 - 2.8e-35 120.9 0.0 3.5e-35 120.6 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC30990.1 - 0.00049 20.3 0.1 0.0019 18.4 0.0 2.0 3 0 0 3 3 3 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.25 EGC30990.1 - 0.013 15.3 1.0 0.12 12.2 0.1 2.6 3 0 0 3 3 3 0 ACT domain Rossmann-like PF10727.9 EGC30990.1 - 0.015 15.1 0.0 0.06 13.2 0.0 2.0 1 1 0 1 1 1 0 Rossmann-like domain PAP2 PF01569.21 EGC30991.1 - 1.1e-10 41.4 3.4 1.1e-10 41.4 3.4 2.6 3 0 0 3 3 3 1 PAP2 superfamily NOA36 PF06524.12 EGC30991.1 - 8.8 5.6 7.0 14 4.9 7.0 1.2 1 0 0 1 1 1 0 NOA36 protein FNIP PF05725.12 EGC30992.1 - 0.016 15.4 17.4 0.35 11.1 0.8 4.4 3 1 0 4 4 4 0 FNIP Repeat ICAT PF06384.11 EGC30992.1 - 0.2 11.9 0.8 0.35 11.1 0.8 1.3 1 0 0 1 1 1 0 Beta-catenin-interacting protein ICAT Pkinase PF00069.25 EGC30993.1 - 3.8e-35 121.5 0.1 5.9e-35 120.9 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC30993.1 - 1e-08 34.8 0.0 3.6e-08 33.0 0.0 1.9 1 1 1 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGC30993.1 - 0.00098 18.5 0.1 0.0034 16.8 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.11 EGC30993.1 - 0.015 14.3 0.2 0.023 13.7 0.2 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase Choline_kinase PF01633.20 EGC30993.1 - 0.077 12.6 0.1 0.14 11.7 0.1 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGC30993.1 - 0.14 12.1 0.0 0.34 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family RNA_pol_A_bac PF01000.26 EGC30994.1 - 9.8e-28 96.8 0.1 4.7e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGC30994.1 - 2.3e-23 81.4 0.0 5.4e-23 80.2 0.0 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ion_trans PF00520.31 EGC30995.1 - 3.4e-11 42.9 10.8 3.4e-11 42.9 10.8 1.4 2 0 0 2 2 2 1 Ion transport protein Holin_BhlA PF10960.8 EGC30995.1 - 0.042 13.8 0.7 3.7 7.6 0.1 2.4 2 0 0 2 2 2 0 BhlA holin family BK_channel_a PF03493.18 EGC30996.1 - 2e-17 63.2 0.1 1.4e-16 60.4 0.0 2.5 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGC30996.1 - 5.4e-11 42.3 2.4 1.1e-10 41.3 2.4 1.6 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.18 EGC30996.1 - 0.0013 19.0 0.0 2.1 8.6 0.0 2.7 3 0 0 3 3 3 2 TrkA-N domain Ion_trans PF00520.31 EGC30996.1 - 0.045 13.0 2.7 0.078 12.2 2.7 1.3 1 0 0 1 1 1 0 Ion transport protein DUF4750 PF15938.5 EGC30997.1 - 1.9e-12 46.6 0.3 2.5e-12 46.3 0.3 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4750) Cas_DxTHG PF09455.10 EGC30997.1 - 0.036 13.7 0.1 0.036 13.7 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated (Cas) DxTHG family LapA_dom PF06305.11 EGC30997.1 - 0.046 13.5 0.1 0.063 13.1 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide assembly protein A domain FoP_duplication PF13865.6 EGC30998.1 - 2.8e-06 27.8 14.7 2.8e-06 27.8 14.7 3.1 1 1 2 3 3 3 1 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L34 PF00468.17 EGC30999.1 - 1.3e-17 63.5 8.8 1.3e-17 63.5 8.8 1.7 2 0 0 2 2 2 1 Ribosomal protein L34 Zip PF02535.22 EGC31000.1 - 1.1e-40 139.9 17.4 5.5e-39 134.3 17.4 2.1 1 1 0 1 1 1 1 ZIP Zinc transporter HupE_UreJ PF04955.12 EGC31000.1 - 3.5 7.0 13.7 2.3 7.7 6.2 2.9 2 2 0 2 2 2 0 HupE / UreJ protein zf-CSL PF05207.13 EGC31001.1 - 9.9e-21 73.2 5.1 1.9e-20 72.4 5.1 1.5 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.31 EGC31001.1 - 1.3e-17 63.7 4.2 2.7e-17 62.6 4.2 1.6 1 1 0 1 1 1 1 DnaJ domain Cpn60_TCP1 PF00118.24 EGC31002.1 - 5.4e-156 520.0 4.7 6.7e-156 519.7 4.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ECH_1 PF00378.20 EGC31003.1 - 1.3e-24 86.9 0.0 1.5e-24 86.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC31003.1 - 2.6e-11 43.6 0.0 3.1e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Laminin_II PF06009.12 EGC31004.1 - 0.007 16.4 2.9 0.018 15.1 0.5 2.7 2 1 0 2 2 2 1 Laminin Domain II Pkinase PF00069.25 EGC31005.1 - 2.6e-78 263.0 0.0 4.1e-78 262.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31005.1 - 5.7e-41 140.5 0.0 8.4e-41 140.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGC31005.1 - 3.5e-15 56.1 0.3 8e-15 55.0 0.3 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.6 EGC31005.1 - 4.1e-11 42.7 0.0 1.3e-10 41.1 0.0 1.8 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGC31005.1 - 2.1e-05 24.0 0.0 3.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Yop-YscD_cpl PF16697.5 EGC31005.1 - 0.0018 18.5 0.0 0.0042 17.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pkinase_fungal PF17667.1 EGC31005.1 - 0.032 13.0 0.0 0.032 13.0 0.0 2.6 3 0 0 3 3 3 0 Fungal protein kinase DEAD PF00270.29 EGC31006.1 - 1.1e-48 165.3 0.2 3.2e-48 163.8 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC31006.1 - 2.5e-31 108.3 0.1 6.2e-29 100.6 0.1 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain TRAPP PF04051.16 EGC31008.1 - 1.8e-45 154.3 0.0 2e-45 154.1 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Zip PF02535.22 EGC31009.1 - 3.3e-47 161.3 12.6 4.2e-47 161.0 12.6 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter TMEMspv1-c74-12 PF11044.8 EGC31009.1 - 0.11 12.5 2.7 6.2 6.9 0.4 2.8 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein RCC1 PF00415.18 EGC31010.1 - 3e-41 139.8 3.6 2.3e-09 37.7 0.0 6.0 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC31010.1 - 9.5e-27 92.2 28.8 3.8e-07 29.7 0.3 7.0 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGC31010.1 - 1.9e-15 57.0 3.9 1.4e-07 31.7 0.5 2.7 2 0 0 2 2 2 2 BTB/POZ domain Ank_2 PF12796.7 EGC31010.1 - 1.3e-11 44.9 0.8 5.2e-06 26.9 0.0 2.3 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC31010.1 - 1.3e-09 38.4 0.0 1.2e-06 29.0 0.0 2.2 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC31010.1 - 7.2e-09 35.7 0.0 2.1e-08 34.3 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC31010.1 - 2e-05 24.6 0.1 0.00021 21.4 0.0 2.9 3 0 0 3 3 3 1 Ankyrin repeat Ank PF00023.30 EGC31010.1 - 0.00056 20.2 0.0 0.0059 17.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat TraS PF10624.9 EGC31011.1 - 1.3 8.9 5.2 0.63 9.9 3.1 1.6 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS DUF4083 PF13314.6 EGC31011.1 - 3.5 7.7 8.6 1 9.3 0.3 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) DUF2207 PF09972.9 EGC31011.1 - 8.1 5.1 8.3 38 2.8 8.3 2.0 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) SAM_decarbox PF01536.16 EGC31012.1 - 9e-107 357.1 0.0 1.1e-106 356.9 0.0 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase Peptidase_S28 PF05577.12 EGC31013.1 - 3.4e-81 273.3 7.3 4.5e-81 272.9 7.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGC31013.1 - 0.078 12.6 0.3 0.34 10.5 0.0 2.2 3 0 0 3 3 3 0 alpha/beta hydrolase fold Arv1 PF04161.13 EGC31014.1 - 1.9e-52 178.5 1.4 2.5e-52 178.1 1.4 1.2 1 0 0 1 1 1 1 Arv1-like family Mpv17_PMP22 PF04117.12 EGC31015.1 - 5.8e-22 77.7 0.9 5.8e-22 77.7 0.9 2.0 2 0 0 2 2 2 1 Mpv17 / PMP22 family TMEM234 PF10639.9 EGC31015.1 - 0.023 14.7 0.2 0.023 14.7 0.2 1.8 2 0 0 2 2 2 0 Putative transmembrane family 234 TauE PF01925.19 EGC31015.1 - 0.055 13.1 4.1 0.2 11.2 4.3 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE HSP70 PF00012.20 EGC31016.1 - 2.7e-139 465.1 3.3 2.7e-139 465.1 3.3 1.8 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGC31016.1 - 3.1e-10 39.4 0.1 1.1e-09 37.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGC31016.1 - 0.0026 17.5 0.0 0.0084 15.9 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SapB_1 PF05184.15 EGC31016.1 - 0.12 12.4 1.0 4.3 7.5 0.1 2.9 2 0 0 2 2 2 0 Saposin-like type B, region 1 CTP_transf_like PF01467.26 EGC31017.1 - 7e-31 107.3 0.4 2.3e-30 105.7 0.1 2.0 2 0 0 2 2 2 1 Cytidylyltransferase-like LMBR1 PF04791.16 EGC31017.1 - 0.66 8.8 12.7 1.2 7.9 2.8 2.1 2 0 0 2 2 2 0 LMBR1-like membrane protein NUC129 PF08157.11 EGC31018.1 - 0.28 11.6 0.2 0.28 11.6 0.2 1.9 2 0 0 2 2 2 0 NUC129 domain adh_short PF00106.25 EGC31019.1 - 6.2e-38 130.2 0.0 8e-38 129.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC31019.1 - 4.5e-23 82.0 0.0 5.7e-23 81.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC31019.1 - 0.00012 22.0 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGC31019.1 - 0.021 14.7 0.0 0.031 14.2 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding Trypan_PARP PF05887.11 EGC31020.1 - 9 6.3 18.4 0.1 12.6 10.4 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Mucin PF01456.17 EGC31020.1 - 9.3 6.2 23.9 20 5.2 23.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MutS_V PF00488.21 EGC31021.1 - 2.8e-82 275.3 0.3 7.2e-82 274.0 0.3 1.8 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGC31021.1 - 1.1e-29 104.0 4.5 4.9e-29 101.9 2.5 2.6 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.18 EGC31021.1 - 8.6e-15 54.9 5.0 8.6e-15 54.9 5.0 2.4 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGC31021.1 - 1.2e-12 48.3 0.1 1.2e-12 48.3 0.1 2.7 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.20 EGC31021.1 - 7.3e-06 26.2 0.2 0.00097 19.4 0.1 2.5 2 0 0 2 2 2 1 MutS domain I Peptidase_M16 PF00675.20 EGC31021.1 - 0.0033 17.4 1.6 0.51 10.3 0.0 2.7 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_27 PF13514.6 EGC31021.1 - 0.059 13.0 0.0 0.15 11.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mating_N PF12731.7 EGC31021.1 - 0.064 13.3 0.2 2.8 8.1 0.0 3.1 3 0 0 3 3 3 0 Mating-type protein beta 1 PB1 PF00564.24 EGC31021.1 - 0.11 12.4 1.2 0.37 10.7 0.8 2.1 1 1 1 2 2 2 0 PB1 domain Glyco_hydro_35 PF01301.19 EGC31022.1 - 2.6e-96 323.0 0.5 2.6e-96 323.0 0.5 2.4 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 NPL4 PF05021.15 EGC31023.1 - 1.1e-24 87.3 0.7 2.6e-14 53.3 0.1 3.4 1 1 1 2 2 2 2 NPL4 family JAB PF01398.21 EGC31023.1 - 1.4e-05 25.1 0.0 2.8e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UN_NPL4 PF11543.8 EGC31023.1 - 0.00085 19.8 0.0 0.0034 17.8 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.10 EGC31023.1 - 0.032 14.9 0.0 0.061 14.0 0.0 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Secretin_N_2 PF07655.13 EGC31023.1 - 3.4 8.3 13.5 0.58 10.7 8.2 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Peptidase_M20 PF01546.28 EGC31024.1 - 7.9e-16 58.4 0.1 1.2e-15 57.8 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DDE_Tnp_4 PF13359.6 EGC31024.1 - 6.6e-14 51.9 0.0 1.2e-13 51.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease M20_dimer PF07687.14 EGC31024.1 - 4.7e-09 36.1 0.1 1.6e-08 34.4 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain DDE_Tnp_1_3 PF13612.6 EGC31024.1 - 0.03 14.3 0.0 0.069 13.2 0.0 1.6 1 0 0 1 1 1 0 Transposase DDE domain NADH_Oxid_Nqo15 PF11497.8 EGC31024.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Kelch_4 PF13418.6 EGC31025.1 - 7.6e-43 144.3 8.1 2.9e-09 36.8 0.2 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC31025.1 - 7.6e-31 105.6 5.0 3.8e-05 23.6 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC31025.1 - 4.4e-27 93.8 5.1 1.7e-06 28.2 0.2 6.7 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC31025.1 - 5.5e-21 74.1 9.3 4.8e-05 23.5 0.2 5.7 4 1 1 5 5 5 5 Kelch motif Kelch_2 PF07646.15 EGC31025.1 - 2.9e-17 61.9 7.7 0.00083 19.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGC31025.1 - 5.2e-16 57.9 11.5 3.2e-05 23.4 0.2 6.2 7 0 0 7 7 7 4 Kelch motif zf-C3HC4_3 PF13920.6 EGC31025.1 - 8.2e-11 41.6 12.9 8.2e-11 41.6 12.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.17 EGC31025.1 - 9.8e-06 25.7 6.7 9.8e-06 25.7 6.7 3.8 2 2 2 4 4 4 1 K-box region Prok-RING_4 PF14447.6 EGC31025.1 - 0.00026 20.8 12.5 0.00054 19.8 12.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 DUF5045 PF16464.5 EGC31025.1 - 0.38 11.1 3.4 0.23 11.8 0.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5045) TIG PF01833.24 EGC31027.1 - 5.2e-06 26.5 24.9 9.5e-06 25.6 2.1 4.5 4 1 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC31027.1 - 3.9e-05 23.9 31.5 0.0003 21.1 11.5 3.2 2 0 0 2 2 2 2 EGF-like domain OST_IS PF18246.1 EGC31027.1 - 0.016 15.5 1.4 19 5.7 0.1 3.8 3 0 0 3 3 3 0 Oligosaccharyltransferase Insert domain Laminin_EGF PF00053.24 EGC31027.1 - 0.12 12.5 22.5 1.4 9.1 8.3 2.9 2 0 0 2 2 2 0 Laminin EGF domain Orf78 PF06024.12 EGC31027.1 - 3 8.2 7.5 2 8.8 0.5 2.8 3 0 0 3 3 3 0 Orf78 (ac78) EGF PF00008.27 EGC31027.1 - 6.8 7.1 27.5 5.1 7.5 9.2 3.6 2 1 0 2 2 2 0 EGF-like domain DSL PF01414.19 EGC31027.1 - 8.7 6.7 22.3 5.9 7.2 7.5 3.2 2 0 0 2 2 2 0 Delta serrate ligand PfkB PF00294.24 EGC31028.1 - 4.6e-11 42.6 0.0 7.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Ank_2 PF12796.7 EGC31029.1 - 0.12 13.0 4.2 0.17 12.5 0.3 3.4 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) CENP-R PF06729.12 EGC31029.1 - 0.9 9.5 5.7 9.7 6.1 0.4 2.7 2 0 0 2 2 2 0 Kinetochore component, CENP-R ELO PF01151.18 EGC31030.1 - 9.6e-62 208.7 24.6 1.2e-61 208.4 24.6 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.8 EGC31030.1 - 0.0041 17.1 0.6 0.0041 17.1 0.6 2.6 2 1 0 2 2 2 1 Protein of unknown function (DUF3290) Myotub-related PF06602.14 EGC31031.1 - 5.7e-136 453.1 2.2 5.7e-136 453.1 2.2 2.8 4 0 0 4 4 4 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.6 EGC31031.1 - 0.027 14.5 0.0 0.027 14.5 0.0 2.6 2 0 0 2 2 2 0 Tyrosine phosphatase family zf-C3HC4_3 PF13920.6 EGC31031.1 - 0.48 10.3 8.8 0.23 11.3 5.2 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DZR PF12773.7 EGC31031.1 - 2.3 8.3 7.7 33 4.6 8.1 2.6 1 1 1 2 2 2 0 Double zinc ribbon E6 PF00518.17 EGC31031.1 - 2.8 8.4 12.5 3.1 8.3 4.7 2.9 2 0 0 2 2 2 0 Early Protein (E6) zf-RING_2 PF13639.6 EGC31033.1 - 2.7e-10 40.4 10.8 4.4e-10 39.7 10.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC31033.1 - 1.5e-08 34.4 7.2 2.3e-08 33.7 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31033.1 - 3.4e-08 33.2 11.2 5.7e-08 32.5 11.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31033.1 - 6.3e-07 29.2 11.0 1.2e-06 28.3 11.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31033.1 - 6.9e-07 29.5 9.1 1.8e-06 28.1 9.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC31033.1 - 6.6e-05 22.7 5.8 0.00013 21.7 5.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC31033.1 - 0.00047 20.0 9.0 0.00083 19.3 9.0 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC31033.1 - 0.0016 18.4 5.1 0.0045 17.0 5.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC31033.1 - 0.016 15.0 10.3 0.03 14.1 10.3 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC31033.1 - 0.05 13.8 4.8 0.11 12.6 4.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 EGC31033.1 - 0.062 13.5 10.4 0.16 12.2 10.4 1.7 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 EGC31033.1 - 0.091 12.5 5.3 0.18 11.6 5.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC31033.1 - 0.092 12.9 10.2 0.13 12.5 8.6 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC31033.1 - 0.12 12.5 4.5 0.25 11.4 4.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EGC31033.1 - 0.23 11.6 6.9 0.44 10.7 6.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC31033.1 - 1.6 8.4 8.3 2.6 7.8 8.3 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 EGC31033.1 - 1.7 8.9 12.2 1.7 8.9 9.7 2.4 1 1 0 1 1 1 0 PHD-like zinc-binding domain FNIP PF05725.12 EGC31034.1 - 3.1e-174 565.0 76.5 1.3e-15 57.3 0.1 13.3 5 2 8 16 16 16 16 FNIP Repeat LRR_1 PF00560.33 EGC31034.1 - 0.13 12.9 13.7 99 4.1 0.0 7.9 7 3 0 7 7 7 0 Leucine Rich Repeat SSURE PF11966.8 EGC31034.1 - 0.21 11.4 12.3 31 4.4 0.0 7.2 8 2 2 10 10 10 0 Fibronectin-binding repeat Thg1 PF04446.12 EGC31035.1 - 1.5e-33 115.5 0.3 6.5e-33 113.4 0.1 1.9 2 0 0 2 2 2 1 tRNAHis guanylyltransferase CDC27 PF09507.10 EGC31036.1 - 0.28 10.5 40.4 0.38 10.1 40.4 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SLC12 PF03522.15 EGC31036.1 - 0.92 8.5 15.2 0.96 8.4 15.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PA26 PF04636.13 EGC31036.1 - 1.3 7.9 10.8 1.5 7.7 10.8 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CDC45 PF02724.14 EGC31036.1 - 2.2 6.4 23.6 2.3 6.4 23.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Trypan_PARP PF05887.11 EGC31036.1 - 3 7.8 20.8 0.016 15.2 9.5 2.0 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AAA_11 PF13086.6 EGC31036.1 - 3.8 7.2 16.2 5 6.8 16.2 1.4 1 0 0 1 1 1 0 AAA domain Zip PF02535.22 EGC31036.1 - 4.3 6.4 10.8 4.7 6.3 10.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter XRN_M PF17846.1 EGC31036.1 - 5 6.0 15.7 6 5.7 15.7 1.1 1 0 0 1 1 1 0 Xrn1 helical domain Paramyxo_ncap PF00973.19 EGC31036.1 - 6.7 5.5 12.2 7.6 5.3 12.2 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein DNA_pol_phi PF04931.13 EGC31036.1 - 8.7 4.3 19.4 11 4.0 19.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi LRR_6 PF13516.6 EGC31037.1 - 6.6e-16 56.9 78.4 0.00096 19.0 0.0 16.5 17 0 0 17 17 17 10 Leucine Rich repeat CopD PF05425.13 EGC31038.1 - 0.0023 18.3 0.7 0.0023 18.3 0.7 3.0 3 1 0 3 3 3 1 Copper resistance protein D Neur_chan_memb PF02932.16 EGC31038.1 - 0.018 15.1 1.2 0.041 13.9 1.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MRAP PF15183.6 EGC31038.1 - 0.14 12.1 0.3 0.14 12.1 0.3 3.5 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family Herpes_LMP1 PF05297.11 EGC31038.1 - 0.2 10.8 1.0 0.61 9.2 0.1 2.2 2 0 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3382 PF11862.8 EGC31038.1 - 2.7 8.3 7.4 3.3 8.1 1.2 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF3382) W2 PF02020.18 EGC31039.1 - 3.1e-20 72.1 8.3 3.1e-20 72.1 8.3 2.7 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.24 EGC31039.1 - 6e-11 41.6 16.9 6.4e-05 22.5 3.5 4.0 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.23 EGC31039.1 - 1e-09 38.4 0.0 2.4e-09 37.1 0.0 1.6 2 0 0 2 2 2 1 Nucleotidyl transferase DUF4954 PF16314.5 EGC31039.1 - 2.5e-05 22.7 0.7 5e-05 21.7 0.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4954) Hexapep_2 PF14602.6 EGC31039.1 - 0.0011 18.6 10.1 0.0018 18.0 1.0 3.6 4 0 0 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF2543 PF10820.8 EGC31039.1 - 0.0052 16.9 0.2 0.015 15.5 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2543) Terminase_3 PF04466.13 EGC31039.1 - 0.0065 16.0 2.0 0.35 10.4 0.1 2.4 2 0 0 2 2 2 2 Phage terminase large subunit NTP_transf_3 PF12804.7 EGC31039.1 - 0.013 15.9 0.0 0.022 15.1 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Fucokinase PF07959.12 EGC31039.1 - 0.13 11.1 0.6 0.26 10.2 0.6 1.4 1 0 0 1 1 1 0 L-fucokinase Cofilin_ADF PF00241.20 EGC31040.1 - 0.00021 21.1 0.1 0.00028 20.7 0.1 1.2 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein RNA_polI_A14 PF08203.11 EGC31040.1 - 0.16 12.7 0.1 1.2 9.9 0.0 2.1 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 PK PF00224.21 EGC31041.1 - 9.9e-151 501.5 9.7 1.3e-150 501.1 9.7 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.16 EGC31041.1 - 3.7e-29 101.3 0.6 1.1e-28 99.8 0.6 1.9 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.14 EGC31041.1 - 7.2e-05 22.0 1.3 0.00015 21.0 1.3 1.6 1 0 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family EGF_2 PF07974.13 EGC31042.1 - 0.25 11.8 9.7 0.61 10.5 9.7 1.7 1 0 0 1 1 1 0 EGF-like domain YajC PF02699.15 EGC31043.1 - 0.014 15.2 0.5 0.032 14.1 0.5 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit PIRT PF15099.6 EGC31043.1 - 0.016 14.8 0.3 0.029 13.9 0.3 1.4 1 0 0 1 1 1 0 Phosphoinositide-interacting protein family SfLAP PF11139.8 EGC31043.1 - 0.02 14.3 0.0 0.026 13.9 0.0 1.1 1 0 0 1 1 1 0 Sap, sulfolipid-1-addressing protein CYYR1 PF10873.8 EGC31043.1 - 0.057 13.9 0.3 0.11 12.9 0.3 1.4 1 0 0 1 1 1 0 Cysteine and tyrosine-rich protein 1 NVEALA PF14055.6 EGC31043.1 - 0.059 13.4 0.5 0.13 12.3 0.5 1.6 1 0 0 1 1 1 0 NVEALA protein EphA2_TM PF14575.6 EGC31043.1 - 0.11 13.4 0.7 0.34 11.8 0.6 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain PsaL PF02605.15 EGC31043.1 - 0.11 12.1 0.2 0.22 11.1 0.2 1.5 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Insulin_TMD PF17870.1 EGC31043.1 - 0.74 9.9 4.7 0.49 10.5 2.5 1.8 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Fz PF01392.22 EGC31044.1 - 0.0012 19.4 5.1 0.0025 18.4 5.1 1.5 1 0 0 1 1 1 1 Fz domain Glyco_hydro_38N PF01074.22 EGC31045.1 - 2.5e-57 194.5 2.8 2.6e-46 158.3 1.1 3.0 2 1 1 3 3 3 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC31045.1 - 1.1e-15 57.5 0.1 3.9e-15 55.8 0.1 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGC31045.1 - 5.8e-13 49.4 1.1 1.6e-12 47.9 1.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain TMEM154 PF15102.6 EGC31045.1 - 0.017 15.1 0.7 0.049 13.5 0.7 1.8 1 0 0 1 1 1 0 TMEM154 protein family HGTP_anticodon PF03129.20 EGC31046.1 - 1.9e-23 82.4 1.9 9.3e-23 80.2 0.0 2.9 3 1 0 3 3 3 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGC31046.1 - 1.4e-12 48.0 0.0 6.4e-12 45.8 0.0 1.9 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Thiamine_BP PF01910.17 EGC31046.1 - 0.065 13.2 0.0 0.19 11.7 0.0 1.8 1 0 0 1 1 1 0 Thiamine-binding protein MTES_1575 PF18741.1 EGC31046.1 - 0.16 12.2 0.0 4.3 7.6 0.0 2.6 2 0 0 2 2 2 0 REase_MTES_1575 zf-C3HC4_3 PF13920.6 EGC31048.1 - 8.5e-09 35.1 7.7 1.4e-08 34.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC31048.1 - 1.5e-08 34.8 10.5 2.5e-08 34.1 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC31048.1 - 8.1e-08 32.0 9.8 2.3e-07 30.6 9.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31048.1 - 3.4e-07 30.0 8.2 5.5e-07 29.3 8.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31048.1 - 1.7e-06 28.2 6.8 4.4e-06 26.9 6.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC31048.1 - 0.00066 19.7 5.1 0.0014 18.6 5.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC31048.1 - 0.0062 16.5 9.9 0.012 15.6 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC31048.1 - 0.013 15.6 9.0 0.04 14.1 8.8 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC31048.1 - 0.062 13.2 8.3 0.21 11.5 8.3 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 EGC31048.1 - 0.072 13.1 6.8 0.21 11.6 6.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon OppC_N PF12911.7 EGC31048.1 - 0.099 12.6 0.1 0.45 10.5 0.1 2.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C zf-RING_10 PF16685.5 EGC31048.1 - 0.43 10.7 4.2 1 9.5 4.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF3021 PF11457.8 EGC31048.1 - 0.46 10.8 4.8 0.67 10.3 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) WBP-1 PF11669.8 EGC31048.1 - 0.51 11.0 0.1 0.51 11.0 0.1 5.5 3 3 0 4 4 2 0 WW domain-binding protein 1 zf-RING_4 PF14570.6 EGC31048.1 - 0.75 9.6 11.4 6.2 6.7 11.3 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC31048.1 - 0.76 9.9 5.2 1.8 8.7 5.2 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC31048.1 - 5.1 6.8 7.4 8.6 6.1 7.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF3430 PF11912.8 EGC31050.1 - 1.6e-34 119.9 19.6 1.6e-34 119.9 19.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) Serglycin PF04360.12 EGC31050.1 - 0.19 11.7 17.0 4.4 7.3 14.1 3.2 2 1 0 2 2 2 0 Serglycin Acetyltransf_1 PF00583.25 EGC31051.1 - 1.7e-13 50.8 0.0 3.4e-06 27.3 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC31051.1 - 9e-11 41.8 0.0 1.7e-05 24.8 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC31051.1 - 1.3e-06 28.7 0.0 0.0027 18.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC31051.1 - 3e-06 27.9 0.0 0.034 14.8 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC31051.1 - 2.8e-05 24.3 0.4 0.00014 22.0 0.0 2.3 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGC31051.1 - 0.0019 17.9 0.0 0.024 14.3 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC31051.1 - 0.0047 16.9 0.0 1 9.4 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_13 PF13880.6 EGC31051.1 - 0.043 13.8 0.0 0.44 10.6 0.0 2.5 2 0 0 2 2 2 0 ESCO1/2 acetyl-transferase FTR PF01913.18 EGC31051.1 - 0.12 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Formylmethanofuran-tetrahydromethanopterin formyltransferase Pkinase PF00069.25 EGC31052.1 - 9.6e-16 57.9 2.5 1.6e-15 57.2 2.5 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31052.1 - 2.9e-13 49.7 0.1 5.2e-13 48.9 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Baculo_IE-1 PF05290.11 EGC31052.1 - 0.00043 20.2 1.9 0.0016 18.4 1.9 1.9 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Pkinase_fungal PF17667.1 EGC31052.1 - 0.00074 18.4 0.0 0.0011 17.8 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGC31052.1 - 0.0011 18.9 0.0 0.0016 18.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.8 EGC31052.1 - 0.012 15.3 0.1 0.028 14.1 0.1 1.6 1 0 0 1 1 1 0 Protein-kinase domain of FAM69 ADD_DNMT3 PF17980.1 EGC31052.1 - 0.68 10.0 6.1 2.6 8.1 6.1 2.0 1 1 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 Pkinase PF00069.25 EGC31053.1 - 3.5e-23 82.3 13.5 1.7e-15 57.1 3.4 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31053.1 - 1.3e-20 73.8 3.0 2.5e-12 46.6 0.2 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.22 EGC31053.1 - 2.1e-08 34.0 0.7 1.4e-05 24.8 0.1 2.6 2 0 0 2 2 2 2 RIO1 family Pkinase_fungal PF17667.1 EGC31053.1 - 7.8e-07 28.2 1.0 7.5e-05 21.7 0.1 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EGC31053.1 - 1.5e-05 25.1 0.0 0.00068 19.6 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGC31053.1 - 0.009 15.4 0.1 5 6.4 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Baculo_IE-1 PF05290.11 EGC31053.1 - 0.01 15.8 13.0 0.15 12.0 0.8 3.2 3 0 0 3 3 3 0 Baculovirus immediate-early protein (IE-0) zf-UDP PF14569.6 EGC31053.1 - 0.3 11.2 1.7 11 6.2 0.0 2.4 2 0 0 2 2 2 0 Zinc-binding RING-finger RPN6_N PF18055.1 EGC31053.1 - 5 7.5 6.9 11 6.4 0.2 3.6 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN6 N-terminal domain zf-RVT PF13966.6 EGC31054.1 - 0.039 14.7 0.5 0.063 14.0 0.5 1.4 1 1 0 1 1 1 0 zinc-binding in reverse transcriptase Pkinase PF00069.25 EGC31055.1 - 6.2e-15 55.3 4.3 9.3e-15 54.7 3.8 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31055.1 - 2.9e-10 39.9 0.1 4.9e-10 39.1 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC31055.1 - 0.00017 21.6 0.0 0.00027 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGC31055.1 - 0.00036 19.6 0.8 0.00077 18.5 0.8 1.6 1 0 0 1 1 1 1 Haspin like kinase domain PIP49_C PF12260.8 EGC31055.1 - 0.0066 16.1 0.6 0.013 15.1 0.6 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 ADD_DNMT3 PF17980.1 EGC31055.1 - 0.28 11.2 4.6 0.81 9.7 4.6 1.8 1 0 0 1 1 1 0 Cysteine rich ADD domain in DNMT3 FixQ PF05545.11 EGC31056.1 - 0.76 9.8 2.9 57 3.8 0.4 3.2 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF1348 PF07080.11 EGC31057.1 - 1.6e-60 202.8 9.2 1.8e-60 202.6 9.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.7 EGC31057.1 - 1.5e-05 25.5 0.0 1.9e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.6 EGC31057.1 - 0.031 14.7 0.0 0.043 14.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SnoaL PF07366.12 EGC31057.1 - 0.1 12.4 0.1 0.15 11.8 0.1 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase TehB PF03848.14 EGC31057.1 - 0.12 11.8 0.1 0.16 11.4 0.1 1.2 1 0 0 1 1 1 0 Tellurite resistance protein TehB SprT-like PF10263.9 EGC31058.1 - 2.8e-20 72.3 0.2 2.8e-20 72.3 0.2 2.2 2 0 0 2 2 2 1 SprT-like family HI0933_like PF03486.14 EGC31058.1 - 0.7 8.5 7.0 1.9 7.1 7.0 1.7 1 0 0 1 1 1 0 HI0933-like protein NPR3 PF03666.13 EGC31059.1 - 0.011 14.6 7.9 0.016 14.1 7.9 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGC31059.1 - 0.078 11.7 4.4 0.11 11.2 4.4 1.2 1 0 0 1 1 1 0 Presenilin CSG2 PF16965.5 EGC31059.1 - 0.36 9.7 5.7 0.61 9.0 5.7 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator ALMT PF11744.8 EGC31059.1 - 0.37 9.6 6.4 0.63 8.8 6.4 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 EGC31059.1 - 0.57 10.3 11.0 0.12 12.4 7.5 1.7 2 0 0 2 2 2 0 Gti1/Pac2 family Tyrosinase PF00264.20 EGC31059.1 - 1.5 9.1 12.7 3.2 8.0 12.7 1.5 1 0 0 1 1 1 0 Common central domain of tyrosinase Dapper PF15268.6 EGC31059.1 - 2.7 6.8 7.0 3.5 6.4 7.0 1.1 1 0 0 1 1 1 0 Dapper Menin PF05053.13 EGC31059.1 - 9.2 4.5 15.3 17 3.6 15.3 1.3 1 0 0 1 1 1 0 Menin DUF1981 PF09324.10 EGC31060.1 - 0.091 12.6 0.8 1.1 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1981) GST_N PF02798.20 EGC31061.1 - 2e-11 44.1 0.1 4.8e-11 42.9 0.1 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC31061.1 - 4.4e-09 36.6 0.0 1.4e-08 35.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC31061.1 - 1e-07 32.0 0.0 2.4e-07 30.9 0.0 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC31061.1 - 2.1e-06 27.7 0.0 4.1e-06 26.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC31061.1 - 5.3e-05 23.4 0.0 0.00015 22.0 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain AnfG_VnfG PF03139.15 EGC31063.1 - 0.014 15.4 0.2 0.14 12.3 0.0 2.3 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit NmrA PF05368.13 EGC31064.1 - 2e-56 191.2 0.2 2.4e-56 190.9 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC31064.1 - 1.1e-08 35.2 0.0 2.1e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC31064.1 - 0.015 14.3 0.1 0.026 13.5 0.1 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC31064.1 - 0.052 13.0 0.1 0.15 11.5 0.1 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family LytR_C PF13399.6 EGC31064.1 - 0.11 13.5 0.2 0.28 12.2 0.2 1.7 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator PBS_linker_poly PF00427.21 EGC31064.1 - 0.14 12.2 1.1 0.4 10.7 0.0 2.3 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide Choline_transpo PF04515.12 EGC31065.1 - 4.4e-103 344.9 32.3 4.4e-103 344.9 32.3 2.9 3 0 0 3 3 3 1 Plasma-membrane choline transporter Abhydrolase_9_N PF15420.6 EGC31065.1 - 2.7 7.9 9.7 2.9 7.9 0.5 3.1 2 1 1 3 3 3 0 Alpha/beta-hydrolase family N-terminus AAA PF00004.29 EGC31066.1 - 1e-44 152.1 0.0 2.7e-44 150.8 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC31066.1 - 2.7e-09 36.7 0.0 6.9e-09 35.4 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC31066.1 - 1.7e-08 34.6 0.1 5.2e-08 33.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Prot_ATP_ID_OB PF16450.5 EGC31066.1 - 2.6e-08 33.7 0.2 8.5e-08 32.0 0.0 1.9 2 0 0 2 2 2 1 Proteasomal ATPase OB C-terminal domain AAA_16 PF13191.6 EGC31066.1 - 1.5e-07 31.9 0.2 4.7e-05 23.8 0.0 2.6 2 1 1 3 3 2 1 AAA ATPase domain AAA_2 PF07724.14 EGC31066.1 - 1.9e-07 31.4 0.0 3.5e-07 30.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGC31066.1 - 3.8e-05 24.0 1.4 0.0084 16.4 0.0 3.1 2 1 1 3 3 3 1 AAA domain RuvB_N PF05496.12 EGC31066.1 - 6.7e-05 22.7 0.0 0.00024 20.9 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain DUF815 PF05673.13 EGC31066.1 - 9.5e-05 21.7 0.0 0.00016 20.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EGC31066.1 - 0.00017 20.9 0.0 0.00033 20.0 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_18 PF13238.6 EGC31066.1 - 0.00053 20.5 0.0 0.0013 19.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC31066.1 - 0.00069 19.9 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGC31066.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein RNA_helicase PF00910.22 EGC31066.1 - 0.0014 19.0 0.0 0.0032 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.21 EGC31066.1 - 0.0015 17.9 0.1 0.0036 16.7 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGC31066.1 - 0.0018 18.0 0.1 0.12 12.1 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.6 EGC31066.1 - 0.0029 17.6 0.0 0.012 15.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain TsaE PF02367.17 EGC31066.1 - 0.0051 16.8 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGC31066.1 - 0.0061 16.1 0.1 0.051 13.1 0.1 2.1 1 1 0 1 1 1 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGC31066.1 - 0.0073 16.1 0.1 0.018 14.8 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGC31066.1 - 0.0088 16.2 0.0 0.017 15.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.6 EGC31066.1 - 0.011 15.3 1.4 0.036 13.6 0.1 2.0 1 1 1 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGC31066.1 - 0.013 15.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_30 PF13604.6 EGC31066.1 - 0.013 15.2 0.1 0.027 14.2 0.1 1.6 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC31066.1 - 0.014 15.3 0.1 0.079 12.9 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_3 PF07726.11 EGC31066.1 - 0.018 14.9 0.0 0.053 13.4 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGC31066.1 - 0.019 14.4 0.1 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 Bacterial TniB protein Parvo_NS1 PF01057.17 EGC31066.1 - 0.019 14.0 0.0 0.044 12.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGC31066.1 - 0.021 14.2 0.6 0.47 9.8 0.0 2.5 3 0 0 3 3 3 0 KaiC NB-ARC PF00931.22 EGC31066.1 - 0.056 12.6 0.0 0.4 9.8 0.0 2.2 2 0 0 2 2 2 0 NB-ARC domain CENP-B_dimeris PF09026.10 EGC31067.1 - 0.006 16.9 2.7 0.0084 16.5 2.7 1.3 1 0 0 1 1 1 1 Centromere protein B dimerisation domain MIEAP PF16026.5 EGC31067.1 - 0.054 13.7 2.4 0.063 13.5 2.4 1.1 1 0 0 1 1 1 0 Mitochondria-eating protein CDC45 PF02724.14 EGC31067.1 - 0.16 10.3 6.6 0.17 10.1 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein FAM176 PF14851.6 EGC31067.1 - 0.34 10.6 4.5 0.59 9.8 4.5 1.4 1 0 0 1 1 1 0 FAM176 family Microvir_H PF04687.12 EGC31067.1 - 1.3 8.3 5.1 1.5 8.1 5.1 1.1 1 0 0 1 1 1 0 Microvirus H protein (pilot protein) SGT1 PF07093.11 EGC31067.1 - 1.8 6.9 13.8 0.55 8.6 9.0 1.9 1 1 1 2 2 2 0 SGT1 protein FAD_binding_3 PF01494.19 EGC31068.1 - 1.4e-19 70.6 0.0 2e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Trp_halogenase PF04820.14 EGC31068.1 - 3.3e-09 36.1 0.0 7.7e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase DAO PF01266.24 EGC31068.1 - 4.7e-08 33.0 0.1 0.0059 16.2 0.0 2.8 3 0 0 3 3 3 2 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGC31068.1 - 6.6e-06 26.6 0.1 8e-05 23.1 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC31068.1 - 2e-05 24.7 0.0 5.9e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGC31068.1 - 2.7e-05 23.6 0.4 0.00058 19.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC31068.1 - 0.00053 19.3 0.1 0.0016 17.8 0.1 1.8 1 1 0 1 1 1 1 Thi4 family Lycopene_cycl PF05834.12 EGC31068.1 - 0.00057 19.0 0.2 0.054 12.5 0.0 2.4 3 0 0 3 3 3 1 Lycopene cyclase protein FAD_binding_2 PF00890.24 EGC31068.1 - 0.0067 15.6 0.0 0.095 11.8 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain HI0933_like PF03486.14 EGC31068.1 - 0.0076 15.0 0.0 0.019 13.7 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein SE PF08491.10 EGC31068.1 - 0.078 12.0 0.0 0.23 10.5 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.16 EGC31068.1 - 0.08 12.6 0.1 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PCRF PF03462.18 EGC31069.1 - 1.5e-42 145.7 0.0 2.6e-42 144.9 0.0 1.4 1 0 0 1 1 1 1 PCRF domain RF-1 PF00472.20 EGC31069.1 - 3.6e-33 113.9 0.2 6.4e-33 113.1 0.2 1.4 1 0 0 1 1 1 1 RF-1 domain Blt1_C PF17183.4 EGC31070.1 - 0.00045 19.7 0.1 0.00081 18.9 0.1 1.4 1 0 0 1 1 1 1 Get5 carboxyl domain APG6_N PF17675.1 EGC31070.1 - 0.024 15.2 0.8 0.024 15.2 0.8 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3446 PF11928.8 EGC31070.1 - 0.03 14.6 0.0 0.038 14.3 0.0 1.2 1 0 0 1 1 1 0 Early growth response N-terminal domain DUF2076 PF09849.9 EGC31071.1 - 0.0047 17.0 3.2 0.0052 16.9 3.2 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) Ntox50 PF15542.6 EGC31071.1 - 0.0057 17.4 5.2 0.0066 17.2 5.2 1.1 1 0 0 1 1 1 1 Bacterial toxin 50 PseudoU_synth_2 PF00849.22 EGC31072.1 - 1.1e-22 80.8 0.0 1.8e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pkinase PF00069.25 EGC31073.1 - 4.6e-82 275.3 0.0 5.2e-82 275.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31073.1 - 2.4e-34 118.8 0.0 4e-34 118.1 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC31073.1 - 0.00012 21.1 0.0 0.00059 18.9 0.0 1.9 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC31073.1 - 0.00021 20.7 0.0 0.03 13.6 0.0 2.7 2 1 1 3 3 3 2 Kinase-like APH PF01636.23 EGC31073.1 - 0.019 14.9 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC31073.1 - 0.037 13.4 0.1 0.066 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.11 EGC31073.1 - 0.089 11.8 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 TPR_1 PF00515.28 EGC31074.1 - 7.9e-27 91.9 17.2 2.9e-09 36.4 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat DnaJ PF00226.31 EGC31074.1 - 4e-26 90.9 4.2 1.1e-25 89.6 4.2 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.17 EGC31074.1 - 3.8e-24 82.8 16.4 3.1e-07 30.0 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31074.1 - 1.8e-14 52.7 15.1 3.8e-05 23.6 0.1 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31074.1 - 4.2e-14 52.8 11.0 4.2e-05 24.0 0.2 5.7 4 1 2 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31074.1 - 4.2e-14 52.9 1.1 7.6e-05 23.3 0.0 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31074.1 - 3.4e-11 42.6 8.9 0.0022 17.7 0.0 5.0 4 1 1 5 5 5 3 TPR repeat TPR_9 PF13371.6 EGC31074.1 - 2.7e-09 37.1 0.4 0.0013 18.9 0.1 2.7 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31074.1 - 8.2e-09 35.3 14.2 0.0027 18.0 0.0 6.3 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31074.1 - 5.7e-08 32.9 2.9 0.047 14.5 0.1 5.4 3 2 3 6 6 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31074.1 - 1.9e-06 28.0 6.9 0.012 15.8 0.1 3.2 2 1 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.6 EGC31074.1 - 0.00015 21.9 6.4 0.096 13.0 1.2 4.2 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31074.1 - 0.0026 17.7 2.1 2.2 8.5 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat BTAD PF03704.17 EGC31074.1 - 0.025 15.0 0.6 0.21 12.0 0.2 2.2 1 1 1 2 2 2 0 Bacterial transcriptional activator domain HSDR_N_2 PF13588.6 EGC31074.1 - 0.042 13.8 0.2 13 5.8 0.0 2.4 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) Forkhead_N PF08430.12 EGC31074.1 - 0.78 10.4 14.3 0.58 10.8 12.4 1.8 2 0 0 2 2 2 0 Forkhead N-terminal region SHNi-TPR PF10516.9 EGC31074.1 - 1.4 8.4 6.0 4.5 6.8 0.1 3.6 4 0 0 4 4 4 0 SHNi-TPR TPR_6 PF13174.6 EGC31074.1 - 2.4 9.0 16.6 3 8.7 0.2 5.8 7 0 0 7 7 6 0 Tetratricopeptide repeat Mt_ATP-synt_D PF05873.12 EGC31074.1 - 5 7.0 9.5 6.2 6.7 3.2 2.3 2 0 0 2 2 2 0 ATP synthase D chain, mitochondrial (ATP5H) TPR_10 PF13374.6 EGC31074.1 - 9.5 6.2 7.7 95 3.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat OapA PF04225.12 EGC31075.1 - 0.037 14.1 0.1 0.22 11.6 0.0 2.3 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain WD40 PF00400.32 EGC31076.1 - 3.6e-05 24.4 8.5 1.3 10.0 0.0 4.8 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC31076.1 - 5.8e-05 23.3 0.0 0.042 14.1 0.0 3.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Zip PF02535.22 EGC31077.1 - 0.0049 16.1 7.1 0.0062 15.8 7.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter CDC45 PF02724.14 EGC31077.1 - 0.048 11.9 22.3 0.065 11.5 22.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF789 PF05623.12 EGC31077.1 - 0.051 13.3 8.3 0.069 12.8 8.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF789) RR_TM4-6 PF06459.12 EGC31077.1 - 0.18 11.6 22.5 0.23 11.2 22.5 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SLC12 PF03522.15 EGC31077.1 - 0.2 10.6 18.4 0.24 10.4 18.4 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EGC31077.1 - 0.22 10.3 15.4 0.3 9.8 15.4 1.2 1 0 0 1 1 1 0 Presenilin Borrelia_P83 PF05262.11 EGC31077.1 - 0.22 10.0 24.7 0.3 9.5 24.7 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein AAA_11 PF13086.6 EGC31077.1 - 0.28 10.9 14.9 0.39 10.4 14.9 1.4 1 0 0 1 1 1 0 AAA domain DUF2151 PF10221.9 EGC31077.1 - 0.33 9.5 17.6 0.4 9.2 17.6 1.2 1 0 0 1 1 1 0 Cell cycle and development regulator SAPS PF04499.15 EGC31077.1 - 0.43 9.3 15.2 0.49 9.1 15.2 1.2 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF2052 PF09747.9 EGC31077.1 - 0.48 10.5 20.1 0.71 10.0 20.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF4228 PF14009.6 EGC31077.1 - 1.4 9.3 7.6 2.4 8.5 7.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) Neur_chan_memb PF02932.16 EGC31077.1 - 1.7 8.7 9.7 2.1 8.4 9.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region CobT PF06213.12 EGC31077.1 - 2.1 7.7 24.4 9.9 5.5 24.4 2.0 1 1 1 2 2 2 0 Cobalamin biosynthesis protein CobT DUF913 PF06025.12 EGC31077.1 - 3.1 6.7 10.9 4.2 6.2 10.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) ALMT PF11744.8 EGC31077.1 - 4.1 6.1 12.5 4.9 5.9 12.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 EGC31077.1 - 5.2 4.9 15.4 6.7 4.5 15.4 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ndc1_Nup PF09531.10 EGC31077.1 - 6.8 5.2 6.3 7 5.2 6.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF5427 PF10310.9 EGC31077.1 - 7 5.5 23.7 9.1 5.1 23.7 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5427) Hid1 PF12722.7 EGC31077.1 - 8.9 4.3 13.4 11 4.0 13.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ribosomal_S3_C PF00189.20 EGC31078.1 - 3.5e-23 81.9 0.2 1.1e-22 80.4 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.17 EGC31078.1 - 7e-10 38.6 0.0 1.1e-09 38.0 0.0 1.3 1 0 0 1 1 1 1 KH domain Coilin_N PF15862.5 EGC31078.1 - 0.089 12.6 0.0 0.16 11.8 0.0 1.3 1 0 0 1 1 1 0 Coilin N-terminus eRF1_2 PF03464.15 EGC31079.1 - 1.9e-45 154.4 0.0 3.3e-45 153.7 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGC31079.1 - 1.3e-35 122.3 0.0 3.1e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.15 EGC31079.1 - 2.5e-18 66.3 0.0 4.1e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 eRF1 domain 1 baeRF_family10 PF18854.1 EGC31079.1 - 2.2e-08 34.5 0.0 3.5e-08 33.8 0.0 1.3 1 0 0 1 1 1 1 Bacterial archaeo-eukaryotic release factor family 10 acVLRF1 PF18859.1 EGC31079.1 - 2.8e-07 30.9 0.0 4.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Actinobacteria/chloroflexi VLRF1 release factor TPR_20 PF14561.6 EGC31080.1 - 2e-29 101.7 0.1 4.7e-28 97.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.20 EGC31080.1 - 1.5e-09 37.7 0.4 9.2e-09 35.2 0.0 2.3 2 0 0 2 2 2 1 Thioredoxin TPR_19 PF14559.6 EGC31080.1 - 4.4e-09 36.7 0.1 0.0099 16.4 0.0 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31080.1 - 0.00016 22.1 2.5 2.7 8.8 0.1 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat Thioredoxin_6 PF13848.6 EGC31080.1 - 0.00027 20.9 0.6 0.00075 19.5 0.6 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain ANAPC3 PF12895.7 EGC31080.1 - 0.00029 21.0 0.3 0.025 14.8 0.1 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.6 EGC31080.1 - 0.00045 20.8 0.0 2.1 9.4 0.0 2.9 3 0 0 3 3 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31080.1 - 0.001 18.7 0.9 0.001 18.7 0.9 3.3 4 0 0 4 4 4 1 TPR repeat TPR_2 PF07719.17 EGC31080.1 - 0.0011 19.0 9.0 0.0059 16.6 0.4 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31080.1 - 0.0019 18.4 1.0 1.1 9.6 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC31080.1 - 0.0032 17.6 0.0 0.53 10.5 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat RPN7 PF10602.9 EGC31080.1 - 0.033 13.9 5.7 1.1 8.9 5.7 2.7 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_16 PF13432.6 EGC31080.1 - 0.077 13.7 0.0 0.31 11.7 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC31080.1 - 0.14 12.0 0.1 2.2 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31080.1 - 0.76 10.1 10.5 0.11 12.8 1.2 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31080.1 - 6.8 7.0 6.2 27 5.1 0.0 3.6 4 0 0 4 4 2 0 Tetratricopeptide repeat MBOAT PF03062.19 EGC31081.1 - 3.8e-31 108.7 32.8 3.8e-31 108.7 32.8 1.9 2 0 0 2 2 2 1 MBOAT, membrane-bound O-acyltransferase family Pkinase PF00069.25 EGC31082.1 - 1.1e-77 261.0 0.1 1.2e-77 260.8 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31082.1 - 3.1e-34 118.4 0.0 3.7e-34 118.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC31082.1 - 2.1e-08 33.9 0.0 1.3e-06 27.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGC31082.1 - 0.00013 22.0 0.0 0.071 13.0 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC31082.1 - 0.00061 18.7 0.1 0.0042 15.9 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGC31082.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC31082.1 - 0.0047 16.6 0.9 0.088 12.4 0.0 2.1 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 RIO1 PF01163.22 EGC31082.1 - 0.033 13.8 0.1 0.057 13.0 0.1 1.3 1 0 0 1 1 1 0 RIO1 family DUF4939 PF16297.5 EGC31082.1 - 0.067 13.1 0.1 2.5 8.0 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4939) PIP5K PF01504.18 EGC31083.1 - 6.8e-85 284.6 11.8 9.1e-85 284.2 11.8 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Glyco_hydro_59 PF02057.15 EGC31083.1 - 0.041 13.1 0.3 0.062 12.5 0.3 1.3 1 0 0 1 1 1 0 Glycosyl hydrolase family 59 Dynamin_M PF01031.20 EGC31084.1 - 3.6e-87 292.2 0.5 3.6e-87 292.2 0.5 3.8 4 0 0 4 4 4 1 Dynamin central region Dynamin_N PF00350.23 EGC31084.1 - 1.7e-54 184.3 0.0 1.7e-54 184.3 0.0 3.6 3 1 0 3 3 3 1 Dynamin family GED PF02212.18 EGC31084.1 - 3e-17 62.5 6.1 3e-17 62.5 6.1 3.5 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.23 EGC31084.1 - 2.7e-05 24.2 0.7 0.00013 22.1 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF2076 PF09849.9 EGC31084.1 - 6e-05 23.2 20.4 6e-05 23.2 20.4 2.0 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) FeoB_N PF02421.18 EGC31084.1 - 0.0031 17.0 0.3 0.28 10.7 0.3 2.7 2 0 0 2 2 2 1 Ferrous iron transport protein B ALGX PF16822.5 EGC31084.1 - 0.067 12.9 6.6 0.14 11.8 6.6 1.4 1 0 0 1 1 1 0 SGNH hydrolase-like domain, acetyltransferase AlgX Popeye PF04831.13 EGC31084.1 - 0.086 13.0 0.0 0.31 11.2 0.0 2.1 2 1 0 2 2 2 0 Popeye protein conserved region TFIIA PF03153.13 EGC31084.1 - 0.3 11.0 21.3 0.021 14.8 14.2 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PNISR PF15996.5 EGC31084.1 - 8.7 6.6 12.9 0.71 10.1 5.1 2.3 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR CBM49 PF09478.10 EGC31085.1 - 4.5e-14 52.5 1.3 6.2e-14 52.1 1.3 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 SH3_10 PF17902.1 EGC31085.1 - 0.079 13.0 0.1 0.5 10.5 0.1 2.0 1 1 0 1 1 1 0 SH3 domain DIM PF08194.12 EGC31085.1 - 0.31 11.3 5.7 3.2 8.1 1.0 2.4 2 0 0 2 2 2 0 DIM protein DUF4135 PF13575.6 EGC31086.1 - 0.023 14.0 0.0 0.049 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) RPW8 PF05659.11 EGC31086.1 - 0.25 11.0 4.9 0.12 12.1 0.9 2.6 2 0 0 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 RPW8 PF05659.11 EGC31087.1 - 0.029 14.1 0.4 0.19 11.4 0.4 2.5 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 DUF4135 PF13575.6 EGC31087.1 - 0.062 12.6 0.6 0.3 10.4 0.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4135) PI3_PI4_kinase PF00454.27 EGC31088.1 - 7.9e-53 179.8 3.0 1.1e-52 179.4 0.5 2.8 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase SMG1 PF15785.5 EGC31088.1 - 4.8e-34 117.8 10.8 2.6e-31 108.7 10.8 3.7 1 1 0 1 1 1 1 Serine/threonine-protein kinase smg-1 FATC PF02260.20 EGC31088.1 - 2e-12 46.7 0.1 4.9e-12 45.4 0.1 1.6 1 0 0 1 1 1 1 FATC domain PhetRS_B1 PF18262.1 EGC31089.1 - 0.057 13.6 1.0 0.074 13.3 1.0 1.5 1 1 0 1 1 1 0 Phe-tRNA synthetase beta subunit B1 domain DUF2600 PF10776.9 EGC31090.1 - 0.03 13.2 0.1 0.037 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) ArfGap PF01412.18 EGC31091.1 - 3.8e-40 136.6 0.0 1.4e-39 134.8 0.0 2.0 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 EGC31091.1 - 1.6e-21 76.8 11.8 1.2e-13 51.5 1.5 3.4 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 EGC31091.1 - 2.8e-09 37.3 14.8 8e-07 29.5 2.4 3.6 3 1 0 3 3 3 2 Pleckstrin homology domain PH_15 PF17339.2 EGC31091.1 - 0.00047 20.0 2.0 0.012 15.4 0.9 2.6 2 0 0 2 2 2 1 PH domain BCL_N PF04714.13 EGC31091.1 - 0.015 15.4 0.3 0.84 9.8 0.2 2.8 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Mcp5_PH PF12814.7 EGC31091.1 - 0.015 15.4 0.8 0.015 15.4 0.8 2.4 2 0 0 2 2 2 0 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.6 EGC31091.1 - 0.081 13.3 2.5 15 6.0 1.0 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain PH_2 PF08458.10 EGC31091.1 - 0.34 11.3 2.7 0.43 11.0 0.7 2.1 2 0 0 2 2 2 0 Plant pleckstrin homology-like region RabGAP-TBC PF00566.18 EGC31092.1 - 3.3e-38 131.5 6.2 2.5e-19 69.8 0.3 2.4 1 1 1 2 2 2 2 Rab-GTPase-TBC domain Glyco_transf_10 PF00852.19 EGC31093.1 - 1.1e-40 139.3 2.1 1.1e-40 139.3 2.1 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_tran_10_N PF17039.5 EGC31093.1 - 0.019 15.4 0.0 0.056 13.9 0.0 1.8 1 0 0 1 1 1 0 Fucosyltransferase, N-terminal Pkinase_Tyr PF07714.17 EGC31095.1 - 8.5e-55 185.8 0.0 1.7e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC31095.1 - 2.6e-54 184.4 0.0 1.2e-53 182.2 0.0 2.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.23 EGC31095.1 - 0.21 11.4 0.5 0.41 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CLPTM1 PF05602.12 EGC31096.1 - 1.7e-127 426.0 10.7 1.7e-127 426.0 10.7 1.9 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.14 EGC31096.1 - 2.4e-05 24.0 3.9 0.037 13.8 0.4 3.0 2 0 0 2 2 2 2 PQ loop repeat RNA_pol_Rpc4 PF05132.14 EGC31096.1 - 0.0093 16.4 0.1 0.013 15.9 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase III RPC4 ABC2_membrane_4 PF12730.7 EGC31096.1 - 0.024 14.6 0.1 0.024 14.6 0.1 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF4834 PF16118.5 EGC31096.1 - 0.066 14.2 5.5 0.08 13.9 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4820 PF16091.5 EGC31096.1 - 0.12 11.8 3.3 0.2 11.0 3.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4611 PF15387.6 EGC31096.1 - 0.22 11.8 11.8 0.46 10.7 11.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RPN2_C PF18004.1 EGC31096.1 - 1.8 8.5 15.4 2.9 7.8 15.4 1.3 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain PBP1_TM PF14812.6 EGC31096.1 - 9.4 6.7 12.0 19 5.7 12.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RTP1_C1 PF10363.9 EGC31098.1 - 6.5e-30 103.6 0.3 1.1e-28 99.6 0.0 2.9 3 1 1 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 RTP1_C2 PF10304.9 EGC31098.1 - 6.5e-10 38.5 0.1 1.5e-09 37.3 0.1 1.7 1 0 0 1 1 1 1 Required for nuclear transport of RNA pol II C-terminus 2 HEAT PF02985.22 EGC31098.1 - 0.00012 22.1 0.0 1 9.8 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Vac14_Fab1_bd PF12755.7 EGC31098.1 - 0.0012 19.4 0.0 2 9.1 0.0 3.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGC31098.1 - 0.011 15.6 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) LPD11 PF18824.1 EGC31098.1 - 0.15 12.1 0.4 8 6.6 0.0 2.9 2 1 1 3 3 3 0 Large polyvalent protein-associated domain 11 Pkinase PF00069.25 EGC31099.1 - 4e-64 216.5 0.1 2.7e-63 213.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31099.1 - 3.7e-28 98.5 0.7 1.1e-19 70.8 0.2 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC31099.1 - 8.6e-06 24.9 0.6 1.3e-05 24.3 0.6 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_C PF00433.24 EGC31099.1 - 1.6e-05 25.5 2.0 4.4e-05 24.1 2.0 1.8 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.23 EGC31099.1 - 0.00037 20.5 0.1 0.28 11.1 0.2 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kinase-like PF14531.6 EGC31099.1 - 0.0081 15.5 2.5 0.029 13.7 0.0 2.7 3 0 0 3 3 3 1 Kinase-like Seadorna_VP7 PF07387.11 EGC31099.1 - 0.0086 15.2 0.1 0.029 13.4 0.0 1.9 2 0 0 2 2 2 1 Seadornavirus VP7 CLIP PF12032.8 EGC31099.1 - 0.012 15.9 0.1 0.03 14.6 0.1 1.6 1 0 0 1 1 1 0 Regulatory CLIP domain of proteinases DUF3896 PF13035.6 EGC31099.1 - 0.016 15.3 3.2 0.068 13.3 3.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Fungal_trans_2 PF11951.8 EGC31099.1 - 0.073 11.9 1.3 0.51 9.1 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Coiled PF05710.12 EGC31100.1 - 0.045 14.6 5.9 0.055 14.3 5.9 1.1 1 0 0 1 1 1 0 Coiled coil PseudoU_synth_2 PF00849.22 EGC31101.1 - 1.3e-10 41.6 0.0 1.3e-10 41.6 0.0 3.4 2 2 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 EGC31101.1 - 0.00024 20.8 0.0 0.0044 16.7 0.0 2.6 1 1 1 2 2 2 1 S4 domain DUF5102 PF17104.5 EGC31101.1 - 0.055 13.5 25.9 0.16 12.0 9.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF5102) Ribosomal_S28e PF01200.18 EGC31101.1 - 0.093 12.7 0.0 0.19 11.8 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein S28e Hpt PF01627.23 EGC31102.1 - 6.3e-09 36.0 0.0 1.1e-08 35.2 0.0 1.4 1 0 0 1 1 1 1 Hpt domain PPR PF01535.20 EGC31102.1 - 0.073 13.4 0.0 0.18 12.1 0.0 1.7 1 1 0 1 1 1 0 PPR repeat Pannexin_like PF12534.8 EGC31102.1 - 1.2 8.2 9.7 1.8 7.6 9.7 1.3 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Macoilin PF09726.9 EGC31102.1 - 1.3 7.5 15.6 1.4 7.4 15.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF2203 PF09969.9 EGC31102.1 - 7.7 7.3 6.3 32 5.3 5.1 2.4 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SEC-C PF02810.15 EGC31103.1 - 2.7e-05 24.0 5.7 5e-05 23.1 5.7 1.5 1 0 0 1 1 1 1 SEC-C motif CHASE5 PF17149.4 EGC31103.1 - 0.056 13.4 0.2 0.23 11.4 0.1 2.1 3 0 0 3 3 3 0 Periplasmic sensor domain found in signal transduction proteins Pept_S41_N PF18294.1 EGC31105.1 - 0.0032 17.4 0.7 0.0038 17.2 0.7 1.4 1 1 0 1 1 1 1 Peptidase S41 N-terminal domain Bundlin PF05307.11 EGC31105.1 - 0.1 12.4 1.7 0.14 12.0 1.7 1.2 1 0 0 1 1 1 0 Bundlin Eaf7 PF07904.13 EGC31106.1 - 2.5e-06 27.8 0.1 2.5e-06 27.8 0.1 2.1 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 DpnI_C PF17726.1 EGC31106.1 - 6.3 7.0 8.4 4.5 7.5 0.2 2.5 2 1 0 2 2 2 0 Dam-replacing HTH domain Fes1 PF08609.10 EGC31107.1 - 4.1e-05 24.4 6.1 4.2e-05 24.3 3.4 2.5 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT PF02985.22 EGC31107.1 - 0.00014 21.8 0.1 0.00074 19.6 0.1 2.3 1 0 0 1 1 1 1 HEAT repeat KIP1 PF07765.12 EGC31107.1 - 0.002 18.2 2.3 0.012 15.7 2.5 2.2 2 0 0 2 2 2 1 KIP1-like protein Arm PF00514.23 EGC31107.1 - 0.0058 16.6 0.1 0.3 11.2 0.1 2.8 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGC31107.1 - 0.06 13.9 0.0 0.15 12.6 0.0 1.7 1 0 0 1 1 1 0 HEAT-like repeat V-ATPase_H_C PF11698.8 EGC31107.1 - 0.14 12.3 2.0 0.24 11.5 0.3 2.2 2 1 0 2 2 2 0 V-ATPase subunit H Glyco_transf_10 PF00852.19 EGC31108.1 - 1.1e-41 142.4 0.8 1.1e-41 142.4 0.8 2.0 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Actin PF00022.19 EGC31109.1 - 1.3e-89 300.7 0.0 1.3e-87 294.1 0.0 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGC31109.1 - 0.0081 15.0 0.0 2.9 6.6 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein NDT80_PhoG PF05224.12 EGC31110.1 - 3.7e-23 82.7 0.4 3.7e-23 82.7 0.4 4.0 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 EGC31110.1 - 9e-10 38.7 0.1 1.8e-09 37.8 0.1 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 EGC31110.1 - 0.00083 18.5 0.2 0.0013 17.8 0.2 1.3 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 CCDC-167 PF15188.6 EGC31110.1 - 0.0052 17.1 0.8 0.018 15.4 0.8 1.9 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 ThrE PF06738.12 EGC31110.1 - 0.012 15.0 0.1 0.025 13.9 0.1 1.5 1 0 0 1 1 1 0 Putative threonine/serine exporter DUF2238 PF09997.9 EGC31110.1 - 0.075 12.8 0.3 0.16 11.7 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) DUF2204 PF09970.9 EGC31110.1 - 0.17 11.5 1.0 0.33 10.6 1.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) MCU PF04678.13 EGC31110.1 - 10 6.2 8.9 0.24 11.5 0.2 2.6 3 0 0 3 3 3 0 Mitochondrial calcium uniporter DSL PF01414.19 EGC31113.1 - 0.051 13.9 23.6 0.056 13.7 16.9 3.0 1 1 1 2 2 2 0 Delta serrate ligand GTP_EFTU PF00009.27 EGC31114.1 - 4.3e-47 160.2 0.0 1.1e-46 158.9 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGC31114.1 - 7.8e-24 84.1 0.1 5.3e-23 81.5 0.0 2.5 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGC31114.1 - 1.8e-05 24.7 0.0 0.012 15.6 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase GTP_EFTU_D2 PF03144.25 EGC31114.1 - 0.00057 20.2 0.4 0.0028 18.0 0.1 2.4 2 0 0 2 2 2 1 Elongation factor Tu domain 2 CUE PF02845.16 EGC31114.1 - 0.0027 17.4 0.5 0.0075 15.9 0.5 1.8 1 0 0 1 1 1 1 CUE domain GTP_EFTU_D4 PF14578.6 EGC31114.1 - 0.004 17.0 0.1 0.0093 15.9 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 CbtA_toxin PF06755.12 EGC31114.1 - 0.0086 16.1 0.1 0.041 13.9 0.0 2.1 2 0 0 2 2 2 1 CbtA_toxin of type IV toxin-antitoxin system HBS1_N PF08938.10 EGC31114.1 - 0.015 15.6 8.5 0.015 15.6 8.5 2.4 2 1 0 2 2 2 0 HBS1 N-terminus AAA_27 PF13514.6 EGC31114.1 - 0.24 11.0 0.1 0.24 11.0 0.1 2.0 2 0 0 2 2 2 0 AAA domain Complex1_LYR PF05347.15 EGC31116.1 - 4.9e-05 23.3 2.2 0.00013 21.9 0.6 2.4 2 1 0 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC31116.1 - 0.012 16.3 0.1 0.022 15.5 0.1 1.5 1 1 0 1 1 1 0 Complex1_LYR-like PH PF00169.29 EGC31117.1 - 1.6e-13 51.1 2.7 1.9e-13 50.8 0.6 2.3 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGC31117.1 - 5.6e-06 26.7 0.9 5.6e-06 26.7 0.9 2.6 2 0 0 2 2 2 1 Pleckstrin homology domain Ubiquitin_5 PF18037.1 EGC31117.1 - 0.079 13.3 0.0 0.2 12.0 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain PH_3 PF14593.6 EGC31117.1 - 0.16 12.1 2.1 0.63 10.2 0.8 2.7 2 1 0 2 2 2 0 PH domain WD40 PF00400.32 EGC31117.1 - 3.3 8.7 6.9 2.6 9.0 0.1 3.9 4 0 0 4 4 4 0 WD domain, G-beta repeat CBM49 PF09478.10 EGC31118.1 - 2.6e-05 24.5 0.2 0.00017 21.8 0.1 2.0 1 1 1 2 2 2 1 Carbohydrate binding domain CBM49 Sds3 PF08598.11 EGC31119.1 - 9.7e-18 65.0 21.2 9.7e-18 65.0 21.2 4.4 2 2 2 4 4 4 2 Sds3-like ALMT PF11744.8 EGC31120.1 - 3 6.6 9.8 4.8 5.9 9.8 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Orf78 PF06024.12 EGC31120.1 - 6.3 7.2 15.0 82 3.6 0.0 2.6 2 0 0 2 2 2 0 Orf78 (ac78) PAN_3 PF08277.12 EGC31121.1 - 0.063 13.1 4.0 0.74 9.7 1.8 2.5 2 0 0 2 2 2 0 PAN-like domain Toxin_ToxA PF11584.8 EGC31121.1 - 0.077 13.0 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Proteinaceous host-selective toxin ToxA DUF202 PF02656.15 EGC31121.1 - 0.25 11.8 1.4 0.6 10.6 0.0 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF202) RhoGEF PF00621.20 EGC31122.1 - 4.9e-44 150.7 2.2 4.9e-44 150.7 2.2 2.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGC31122.1 - 0.00024 21.6 0.0 0.00083 19.8 0.0 2.0 1 0 0 1 1 1 1 PH domain PH_16 PF17838.1 EGC31122.1 - 0.00027 20.8 0.0 0.00087 19.1 0.0 1.9 1 0 0 1 1 1 1 PH domain CLN3 PF02487.17 EGC31123.1 - 0.71 8.9 3.2 2.2 7.2 0.2 2.0 2 0 0 2 2 2 0 CLN3 protein Prion_bPrPp PF11587.8 EGC31123.1 - 1.8 8.4 6.4 0.14 12.0 1.5 1.7 2 0 0 2 2 2 0 Major prion protein bPrPp - N terminal NuA4 PF09340.10 EGC31124.1 - 1.1e-22 79.7 1.0 1.1e-22 79.7 1.0 2.8 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 CDC45 PF02724.14 EGC31124.1 - 0.1 10.8 33.5 0.14 10.4 33.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGC31124.1 - 0.38 9.5 21.0 0.54 9.0 21.0 1.4 1 0 0 1 1 1 0 Presenilin DUF4175 PF13779.6 EGC31124.1 - 1.5 6.6 13.7 2.4 6.0 13.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4746 PF15928.5 EGC31124.1 - 3.8 6.8 24.5 6 6.2 24.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) ALMT PF11744.8 EGC31124.1 - 5.8 5.6 16.4 10 4.9 16.4 1.5 1 0 0 1 1 1 0 Aluminium activated malate transporter SLC12 PF03522.15 EGC31124.1 - 7.9 5.4 26.6 12 4.8 26.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 PIG-S PF10510.9 EGC31124.1 - 8.3 5.1 10.1 9.4 4.9 10.1 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-glycan biosynthesis class S protein LRR_6 PF13516.6 EGC31125.1 - 2.5e-06 27.1 43.2 0.022 14.8 0.7 12.3 13 0 0 13 13 13 3 Leucine Rich repeat LRR_1 PF00560.33 EGC31125.1 - 0.0009 19.5 31.2 3.7 8.5 0.0 11.8 11 2 0 11 11 11 2 Leucine Rich Repeat LRR_8 PF13855.6 EGC31125.1 - 0.021 14.6 28.8 1.1 9.1 0.2 8.5 6 3 2 8 8 8 0 Leucine rich repeat LRR_4 PF12799.7 EGC31125.1 - 0.058 13.8 37.5 3.9 8.0 1.4 8.3 6 3 3 9 9 9 0 Leucine Rich repeats (2 copies) FSA_C PF10479.9 EGC31125.1 - 3.7 5.6 12.7 5.6 5.0 12.7 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TetR_C_4 PF08359.11 EGC31126.1 - 0.1 12.7 2.7 0.21 11.7 0.2 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Ku_PK_bind PF08785.11 EGC31126.1 - 0.11 12.7 5.0 0.068 13.3 2.6 2.0 2 0 0 2 2 2 0 Ku C terminal domain like DUF1840 PF08895.11 EGC31126.1 - 0.58 10.5 4.3 2.9 8.3 3.4 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Syntaxin-6_N PF09177.11 EGC31126.1 - 2.5 8.7 11.5 0.17 12.5 3.0 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal Gastrin PF00918.17 EGC31126.1 - 3.2 8.7 7.1 1.9 9.5 2.6 2.3 2 0 0 2 2 2 0 Gastrin/cholecystokinin family DUF2115 PF09888.9 EGC31126.1 - 3.5 8.1 11.2 0.48 10.9 2.7 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) RRM_1 PF00076.22 EGC31127.1 - 3.5e-18 65.2 0.1 5.4e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC31127.1 - 0.00037 20.5 0.0 0.00065 19.7 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif RRM_occluded PF16842.5 EGC31127.1 - 0.00087 19.1 0.1 0.002 18.0 0.1 1.6 1 1 0 1 1 1 1 Occluded RNA-recognition motif RRM_5 PF13893.6 EGC31127.1 - 0.0011 18.5 0.0 0.0017 18.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGC31127.1 - 0.12 12.3 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 RL domain Profilin PF00235.19 EGC31128.1 - 8.4e-28 97.2 0.0 9.3e-28 97.0 0.0 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.19 EGC31129.1 - 1.2e-20 74.0 0.1 1.3e-20 73.9 0.1 1.0 1 0 0 1 1 1 1 Profilin SUR7 PF06687.12 EGC31131.1 - 0.00041 20.0 8.1 0.00041 20.0 8.1 2.9 2 1 1 3 3 3 1 SUR7/PalI family Pox_A14 PF05767.12 EGC31131.1 - 1.1 9.4 7.9 26 5.1 0.5 3.3 3 0 0 3 3 3 0 Poxvirus virion envelope protein A14 TcpE PF12648.7 EGC31131.1 - 2.5 8.7 7.5 2 9.0 2.9 2.4 2 0 0 2 2 2 0 TcpE family Ribosomal_L22 PF00237.19 EGC31133.1 - 3.4e-33 113.9 0.2 4.6e-33 113.5 0.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ASL_C2 PF14698.6 EGC31133.1 - 0.047 14.4 0.5 0.19 12.5 0.5 2.0 1 1 0 1 1 1 0 Argininosuccinate lyase C-terminal ABC_tran PF00005.27 EGC31134.1 - 4.3e-46 156.8 12.9 9.5e-23 81.2 0.0 4.0 3 1 1 4 4 4 2 ABC transporter ABC_tran_Xtn PF12848.7 EGC31134.1 - 5.5e-26 90.4 5.4 5.5e-26 90.4 5.4 3.1 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.6 EGC31134.1 - 9.8e-16 58.4 6.6 0.00038 20.4 0.3 4.5 3 1 1 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC31134.1 - 1.5e-07 31.1 1.5 0.032 13.7 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGC31134.1 - 1e-06 29.2 0.0 0.057 13.8 0.0 3.8 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGC31134.1 - 1.7e-06 28.1 0.1 0.058 13.3 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_23 PF13476.6 EGC31134.1 - 5.1e-06 27.1 20.2 0.027 15.0 0.1 4.3 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGC31134.1 - 8.6e-06 26.2 0.0 0.071 13.5 0.0 2.9 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGC31134.1 - 9.2e-06 26.2 6.2 0.046 14.3 0.1 4.2 4 1 0 4 4 3 2 AAA domain AAA_29 PF13555.6 EGC31134.1 - 1e-05 25.1 0.4 0.039 13.7 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC31134.1 - 2e-05 24.9 0.0 0.17 12.2 0.0 2.9 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC31134.1 - 4.6e-05 23.5 1.0 0.091 12.8 0.3 3.1 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_30 PF13604.6 EGC31134.1 - 6.5e-05 22.7 0.0 0.33 10.6 0.0 3.0 2 1 0 2 2 2 2 AAA domain cobW PF02492.19 EGC31134.1 - 9.8e-05 22.0 1.8 0.32 10.6 0.1 2.6 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_24 PF13479.6 EGC31134.1 - 0.00019 21.2 0.9 0.61 9.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain AAA_33 PF13671.6 EGC31134.1 - 0.0003 20.9 10.3 0.059 13.5 0.0 4.2 4 1 0 4 4 4 2 AAA domain AAA_5 PF07728.14 EGC31134.1 - 0.00035 20.6 0.9 1.2 9.1 0.0 3.7 4 0 0 4 4 3 1 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EGC31134.1 - 0.00046 19.9 0.2 1.3 8.7 0.0 2.7 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGC31134.1 - 0.0005 20.1 0.4 0.49 10.4 0.1 2.5 2 0 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_28 PF13521.6 EGC31134.1 - 0.00057 20.2 6.6 0.22 11.8 0.3 3.0 3 0 0 3 3 2 2 AAA domain RsgA_GTPase PF03193.16 EGC31134.1 - 0.00059 19.8 2.4 0.32 10.9 0.1 2.8 2 1 0 2 2 2 2 RsgA GTPase MobB PF03205.14 EGC31134.1 - 0.00073 19.4 0.3 0.4 10.6 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B NB-ARC PF00931.22 EGC31134.1 - 0.0012 18.1 0.1 0.96 8.6 0.0 2.7 2 0 0 2 2 2 1 NB-ARC domain AAA_14 PF13173.6 EGC31134.1 - 0.0012 18.8 0.1 4 7.5 0.0 3.4 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 EGC31134.1 - 0.0016 18.6 0.3 2.2 8.5 0.1 2.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGC31134.1 - 0.0022 18.4 0.0 0.98 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_7 PF12775.7 EGC31134.1 - 0.0025 17.4 0.0 2.8 7.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region SRP54 PF00448.22 EGC31134.1 - 0.0046 16.6 0.4 1.4 8.5 0.1 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain T2SSE PF00437.20 EGC31134.1 - 0.005 15.9 0.1 0.88 8.6 0.0 2.5 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_25 PF13481.6 EGC31134.1 - 0.0053 16.4 0.1 1.2 8.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain NTPase_1 PF03266.15 EGC31134.1 - 0.0057 16.6 0.2 1.6 8.6 0.0 2.7 2 0 0 2 2 2 1 NTPase DUF3584 PF12128.8 EGC31134.1 - 0.0061 14.2 0.1 0.0061 14.2 0.1 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) AAA_15 PF13175.6 EGC31134.1 - 0.0083 15.9 18.7 0.04 13.6 0.1 4.6 3 1 1 4 4 3 2 AAA ATPase domain AAA_19 PF13245.6 EGC31134.1 - 0.039 14.3 3.4 5.9 7.2 0.0 3.2 3 0 0 3 3 2 0 AAA domain Arf PF00025.21 EGC31134.1 - 0.039 13.4 0.6 1 8.8 0.1 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family FeoB_N PF02421.18 EGC31134.1 - 0.064 12.8 0.5 2.9 7.4 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B ATP-synt_ab PF00006.25 EGC31134.1 - 0.086 12.5 0.0 5.2 6.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Pox_A32 PF04665.12 EGC31134.1 - 0.089 12.2 4.4 2.7 7.4 0.1 3.2 2 1 1 3 3 3 0 Poxvirus A32 protein Zeta_toxin PF06414.12 EGC31134.1 - 0.2 10.9 4.5 0.52 9.5 0.0 3.0 3 0 0 3 3 3 0 Zeta toxin ATPase_2 PF01637.18 EGC31134.1 - 1.9 8.3 6.2 1.6 8.6 0.0 3.1 4 0 0 4 4 3 0 ATPase domain predominantly from Archaea Dynamin_N PF00350.23 EGC31134.1 - 4 7.5 6.5 11 6.1 0.1 3.6 4 0 0 4 4 3 0 Dynamin family Thymidylate_kin PF02223.17 EGC31134.1 - 4.7 6.8 10.0 9.6 5.8 0.0 3.8 4 0 0 4 4 3 0 Thymidylate kinase FNIP PF05725.12 EGC31136.1 - 1.1e-35 121.5 28.1 1.6e-11 44.1 1.5 4.7 4 0 0 4 4 4 4 FNIP Repeat UPF0121 PF03661.13 EGC31136.1 - 3.4e-29 101.9 15.2 5.5e-29 101.3 15.2 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) FNIP PF05725.12 EGC31137.1 - 2.1e-75 248.7 56.0 5.4e-13 48.9 0.1 11.6 5 3 6 12 12 12 12 FNIP Repeat PH_RBD PF12068.8 EGC31138.1 - 1.1e-57 194.2 0.3 2.9e-57 192.8 0.3 1.8 1 0 0 1 1 1 1 Rab-binding domain (RBD) RabGAP-TBC PF00566.18 EGC31138.1 - 2.5e-42 145.0 11.0 2.5e-42 145.0 11.0 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ADH_N_2 PF16884.5 EGC31139.1 - 1.9e-19 69.6 0.0 4.1e-19 68.5 0.0 1.6 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGC31139.1 - 1.9e-15 57.0 0.0 2.8e-15 56.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC31139.1 - 5.5e-06 27.5 0.0 9.6e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.25 EGC31141.1 - 1.2e-17 64.3 0.0 1.4e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC31141.1 - 1.4e-11 44.6 0.0 2e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC31141.1 - 1.9e-11 44.0 0.0 2.7e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC31141.1 - 7.9e-09 35.4 0.1 1.2e-08 34.8 0.1 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.7 EGC31141.1 - 0.00083 19.5 0.1 0.00093 19.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.6 EGC31141.1 - 0.0023 17.6 0.0 0.003 17.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC31141.1 - 0.018 15.1 0.0 0.029 14.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC31141.1 - 0.073 13.7 0.0 0.081 13.6 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.6 EGC31141.1 - 0.17 11.9 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MetW PF07021.12 EGC31143.1 - 0.11 12.1 0.1 1.1 8.8 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Terminase_6C PF17289.2 EGC31143.1 - 0.14 12.3 0.0 0.21 11.7 0.0 1.2 1 0 0 1 1 1 0 Terminase RNaseH-like domain Palm_thioest PF02089.15 EGC31144.1 - 1.9e-56 191.6 0.8 2.2e-56 191.4 0.8 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGC31144.1 - 1.3e-05 24.9 0.0 1.8e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_6 PF12697.7 EGC31144.1 - 0.058 14.0 0.0 0.073 13.7 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF3089 PF11288.8 EGC31144.1 - 0.06 12.9 0.0 0.093 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) TPR_1 PF00515.28 EGC31145.1 - 9e-10 38.0 0.5 3.4e-05 23.5 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31145.1 - 4.4e-08 32.6 0.3 0.00028 20.7 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31145.1 - 5.4e-06 26.2 0.5 0.0018 18.3 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31145.1 - 4.2e-05 23.7 0.0 0.011 16.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31145.1 - 0.016 15.8 0.0 0.038 14.6 0.0 1.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31145.1 - 0.02 14.9 0.1 0.1 12.7 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31145.1 - 0.036 14.5 0.2 2.9 8.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31145.1 - 0.31 10.8 0.1 0.31 10.8 0.1 2.6 3 1 1 4 4 4 0 TPR repeat DUF676 PF05057.14 EGC31146.1 - 2.3e-39 135.2 4.1 3.2e-39 134.7 0.5 2.4 2 1 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGC31146.1 - 2.5e-07 30.8 0.1 5.1e-07 29.8 0.0 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGC31146.1 - 2.3e-06 27.5 0.0 6e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EGC31146.1 - 5.1e-05 22.6 0.0 0.00011 21.5 0.0 1.5 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Lipase_3 PF01764.25 EGC31146.1 - 0.00036 20.4 0.1 0.0011 18.9 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) Lipase_2 PF01674.18 EGC31146.1 - 0.00052 19.6 0.2 0.0015 18.1 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 2) Hydrolase_4 PF12146.8 EGC31146.1 - 0.0083 15.4 0.0 0.12 11.6 0.0 2.2 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase PF00151.19 EGC31146.1 - 0.02 14.2 0.1 0.02 14.2 0.1 1.6 2 0 0 2 2 2 0 Lipase DUF2235 PF09994.9 EGC31146.1 - 0.07 12.5 0.0 0.12 11.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized alpha/beta hydrolase domain (DUF2235) DUF1647 PF07801.11 EGC31146.1 - 0.63 9.8 5.8 0.5 10.1 0.1 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1647) FMO-like PF00743.19 EGC31147.1 - 4.1e-58 197.1 5.9 5.9e-58 196.6 5.9 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGC31147.1 - 2.6e-11 43.4 0.0 4e-10 39.4 0.0 2.3 1 1 1 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGC31147.1 - 8.9e-07 28.4 0.0 2e-06 27.3 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGC31147.1 - 2.7e-06 26.8 0.9 1.5e-05 24.3 0.1 2.5 1 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.6 EGC31147.1 - 0.011 15.7 0.0 0.14 12.1 0.0 2.7 2 1 0 2 2 2 0 FAD-NAD(P)-binding NAD_binding_8 PF13450.6 EGC31147.1 - 0.015 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Arm PF00514.23 EGC31148.1 - 8.9e-06 25.6 1.3 0.95 9.6 0.0 5.4 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Caldesmon PF02029.15 EGC31148.1 - 0.00073 18.4 8.2 0.0011 17.8 8.2 1.5 1 0 0 1 1 1 1 Caldesmon RICTOR_V PF14668.6 EGC31148.1 - 0.036 14.3 0.2 7.3 6.9 0.0 3.2 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 EGC31148.1 - 0.041 14.3 0.0 0.94 9.9 0.0 3.3 4 0 0 4 4 4 0 HEAT repeats WD40 PF00400.32 EGC31149.1 - 5e-25 87.3 17.0 3.9e-06 27.5 0.2 7.9 7 0 0 7 7 7 6 WD domain, G-beta repeat Bromodomain PF00439.25 EGC31149.1 - 2.9e-14 52.9 0.9 2.9e-14 52.9 0.9 2.5 2 0 0 2 2 2 1 Bromodomain Auxin_resp PF06507.13 EGC31149.1 - 1.7e-05 25.0 0.0 4.4e-05 23.7 0.0 1.7 1 0 0 1 1 1 1 Auxin response factor DUF3439 PF11921.8 EGC31149.1 - 0.0046 16.9 3.4 0.0046 16.9 3.4 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3439) Nepo_coat_C PF03688.14 EGC31150.1 - 0.075 12.9 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Imm1 PF14430.6 EGC31150.1 - 0.1 13.3 0.1 0.2 12.3 0.1 1.6 1 1 0 1 1 1 0 Immunity protein Imm1 Rap_GAP PF02145.15 EGC31151.1 - 1.1e-66 223.9 9.3 3.4e-66 222.4 5.4 3.0 2 1 0 2 2 2 2 Rap/ran-GAP FNIP PF05725.12 EGC31152.1 - 2.7e-107 350.7 54.5 8.1e-17 61.1 1.5 9.1 6 1 4 10 10 10 10 FNIP Repeat FNIP PF05725.12 EGC31153.1 - 8.1e-96 314.0 40.8 3.4e-15 55.9 0.2 10.6 9 1 0 10 10 10 7 FNIP Repeat zf-B_box PF00643.24 EGC31153.1 - 5.9e-05 23.1 4.9 9.6e-05 22.5 4.9 1.3 1 0 0 1 1 1 1 B-box zinc finger Mito_fiss_reg PF05308.11 EGC31153.1 - 0.11 12.6 2.1 0.22 11.6 2.1 1.5 1 0 0 1 1 1 0 Mitochondrial fission regulator UL16 PF17622.2 EGC31153.1 - 0.11 12.1 1.5 17 5.0 0.0 3.1 3 1 0 3 3 3 0 Viral unique long protein 16 zf-UBR PF02207.20 EGC31153.1 - 0.14 12.3 2.2 0.27 11.4 2.2 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Oxidored_FMN PF00724.20 EGC31154.1 - 9.2e-72 242.2 0.0 1.1e-71 241.9 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGC31154.1 - 0.0067 15.6 0.0 0.027 13.6 0.0 1.8 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Pkinase PF00069.25 EGC31155.1 - 2.6e-66 223.7 0.1 4.9e-41 140.8 0.6 2.8 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31155.1 - 3.3e-31 108.5 0.0 1.5e-23 83.4 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.24 EGC31155.1 - 8.9e-21 74.0 0.5 3.7e-20 72.0 0.5 2.2 1 0 0 1 1 1 1 PX domain PH PF00169.29 EGC31155.1 - 1.7e-19 70.2 0.0 1.7e-19 70.2 0.0 3.0 3 0 0 3 3 3 1 PH domain Kinase-like PF14531.6 EGC31155.1 - 7.9e-05 22.1 0.0 0.016 14.6 0.0 2.5 2 0 0 2 2 2 2 Kinase-like PH_8 PF15409.6 EGC31155.1 - 0.0022 18.2 0.0 0.0081 16.4 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.23 EGC31155.1 - 0.018 15.0 0.1 0.03 14.2 0.1 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PH_9 PF15410.6 EGC31155.1 - 0.027 14.9 0.1 0.64 10.4 0.1 2.8 1 1 0 1 1 1 0 Pleckstrin homology domain PH_11 PF15413.6 EGC31155.1 - 6 7.3 12.5 0.12 12.8 1.1 4.0 3 1 0 3 3 3 0 Pleckstrin homology domain DUF1084 PF06454.11 EGC31156.1 - 4.5e-24 85.3 14.5 1.4e-15 57.5 10.8 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) PBP1_TM PF14812.6 EGC31156.1 - 0.37 11.2 1.5 0.79 10.1 1.5 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Ost5 PF05251.12 EGC31156.1 - 3.9 7.8 9.9 1.3 9.4 0.6 4.0 3 1 1 4 4 4 0 Oligosaccharyltransferase subunit 5 CARD_2 PF16739.5 EGC31158.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 Caspase recruitment domain VBS PF08913.10 EGC31158.1 - 0.21 12.1 0.0 0.51 10.8 0.0 1.7 1 0 0 1 1 1 0 Vinculin Binding Site ABC2_membrane PF01061.24 EGC31159.1 - 2.3e-76 255.9 56.7 7.8e-44 149.6 24.4 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC31159.1 - 1.3e-38 132.6 0.7 8.3e-18 65.2 0.0 2.9 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGC31159.1 - 2.9e-30 104.0 3.1 2.4e-20 72.2 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC31159.1 - 1.1e-07 32.4 2.6 4.8e-07 30.3 2.6 2.0 1 1 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGC31159.1 - 9.8e-07 28.8 0.3 0.00029 20.8 0.2 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC31159.1 - 1.7e-05 24.5 0.2 0.0062 16.3 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC31159.1 - 2e-05 24.6 1.3 0.065 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system MMR_HSR1 PF01926.23 EGC31159.1 - 0.0005 20.1 0.0 0.32 11.1 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGC31159.1 - 0.0013 19.0 0.1 0.59 10.4 0.1 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC31159.1 - 0.0021 17.7 0.1 0.0063 16.1 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC31159.1 - 0.003 17.9 0.0 0.67 10.3 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGC31159.1 - 0.01 16.2 0.2 6.3 7.2 0.1 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGC31159.1 - 0.014 15.1 0.2 2.5 7.8 0.3 2.3 2 0 0 2 2 2 0 AAA domain Rad17 PF03215.15 EGC31159.1 - 0.03 14.2 0.0 2.2 8.2 0.0 2.7 2 0 0 2 2 2 0 Rad17 P-loop domain Zeta_toxin PF06414.12 EGC31159.1 - 0.059 12.6 0.0 2.4 7.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EGC31159.1 - 0.094 12.3 0.2 0.83 9.2 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGC31159.1 - 0.096 12.8 0.0 0.57 10.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC31159.1 - 0.11 13.0 4.8 0.91 10.1 0.0 3.1 3 0 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 EGC31159.1 - 0.16 11.7 0.0 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_28 PF13521.6 EGC31159.1 - 0.34 11.1 0.7 0.9 9.8 0.3 1.9 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 EGC31159.1 - 0.76 8.8 62.1 0.0049 16.0 27.3 4.1 3 1 0 3 3 3 0 ABC-2 family transporter protein Pkinase_Tyr PF07714.17 EGC31160.1 - 1.4e-54 185.1 0.0 2.7e-54 184.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC31160.1 - 5.3e-46 157.1 0.1 1.2e-45 155.9 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.7 EGC31160.1 - 2.2e-26 92.2 2.4 2.3e-09 37.7 0.4 3.6 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC31160.1 - 4.7e-26 90.8 6.7 2e-08 34.6 0.1 6.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EGC31160.1 - 1.3e-20 72.8 0.5 0.00053 20.3 0.2 6.0 6 0 0 6 6 5 5 Ankyrin repeat Ank_3 PF13606.6 EGC31160.1 - 5e-20 69.5 1.1 0.00017 21.8 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat Ank_5 PF13857.6 EGC31160.1 - 1.5e-18 66.6 3.6 1e-05 25.7 0.5 5.8 4 2 1 5 5 5 3 Ankyrin repeats (many copies) SAM_1 PF00536.30 EGC31160.1 - 2e-10 40.9 0.6 4.7e-10 39.8 0.6 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC31160.1 - 3.3e-07 30.3 0.3 8.6e-07 29.0 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Haspin_kinase PF12330.8 EGC31160.1 - 0.00018 20.5 0.2 0.028 13.4 0.0 2.7 2 0 0 2 2 2 1 Haspin like kinase domain DUF3013 PF11217.8 EGC31160.1 - 0.0094 15.8 0.4 0.022 14.6 0.4 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3013) APH PF01636.23 EGC31160.1 - 0.14 12.1 0.2 0.33 10.8 0.2 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family Dicty_CAR PF05462.11 EGC31161.1 - 2.1e-177 588.7 17.8 2.5e-177 588.4 17.8 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGC31161.1 - 1.1e-08 34.7 16.2 1.1e-08 34.7 16.2 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) CbiQ PF02361.16 EGC31161.1 - 0.63 9.6 6.6 0.058 13.0 1.8 1.8 2 1 0 2 2 2 0 Cobalt transport protein Git3 PF11710.8 EGC31161.1 - 5.4 6.7 21.5 0.047 13.5 10.4 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 EFP_N PF08207.12 EGC31162.1 - 2.1e-13 50.1 2.3 2.4e-13 49.9 0.3 2.0 2 0 0 2 2 2 1 Elongation factor P (EF-P) KOW-like domain DUF702 PF05142.12 EGC31163.1 - 0.019 15.4 8.7 0.019 15.4 8.7 4.9 3 2 0 4 4 4 0 Domain of unknown function (DUF702) Neuroparsin PF07327.11 EGC31163.1 - 0.75 10.3 4.8 1.6 9.2 4.8 1.4 1 0 0 1 1 1 0 Neuroparsin ATP-synt_S1 PF05827.12 EGC31164.1 - 0.00038 20.3 0.5 0.001 18.9 0.5 1.8 1 1 0 1 1 1 1 Vacuolar ATP synthase subunit S1 (ATP6S1) DDE_3 PF13358.6 EGC31164.1 - 0.0047 16.7 0.1 0.1 12.4 0.0 2.1 2 0 0 2 2 2 1 DDE superfamily endonuclease P-II PF00543.22 EGC31164.1 - 0.039 14.6 0.5 11 6.7 0.3 2.4 2 0 0 2 2 2 0 Nitrogen regulatory protein P-II MGS PF02142.22 EGC31164.1 - 0.081 13.1 0.3 0.26 11.5 0.0 2.0 2 0 0 2 2 2 0 MGS-like domain Radical_SAM_N PF08497.10 EGC31164.1 - 0.082 12.1 0.4 0.14 11.4 0.4 1.3 1 0 0 1 1 1 0 Radical SAM N-terminal HATPase_c PF02518.26 EGC31166.1 - 6.9e-27 94.2 0.2 1.8e-25 89.6 0.2 3.0 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC31166.1 - 1e-26 93.3 0.3 2.7e-26 91.9 0.3 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGC31166.1 - 8.9e-12 44.9 1.3 2e-11 43.7 0.1 2.4 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.25 EGC31166.1 - 8.7e-06 25.7 0.0 0.0032 17.5 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.7 EGC31166.1 - 0.0053 17.0 6.3 0.76 10.1 0.0 4.2 4 0 0 4 4 4 1 PAS domain PAS_8 PF13188.7 EGC31166.1 - 0.0068 16.4 0.0 0.019 15.0 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.10 EGC31166.1 - 0.033 14.5 0.0 2.4 8.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold TetR_C_9 PF14514.6 EGC31166.1 - 0.044 13.9 0.0 0.21 11.7 0.0 2.1 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Anillin_N PF16018.5 EGC31166.1 - 0.2 12.3 0.0 0.2 12.3 0.0 2.9 3 0 0 3 3 3 0 Anillin N-terminus DHHC PF01529.20 EGC31167.1 - 1.7e-31 109.1 13.3 1.7e-31 109.1 13.3 2.8 2 2 0 2 2 2 1 DHHC palmitoyltransferase CrgA PF06781.12 EGC31167.1 - 0.39 10.8 1.0 1 9.5 0.1 2.2 2 0 0 2 2 2 0 Cell division protein CrgA SieB PF14163.6 EGC31167.1 - 0.91 9.0 4.2 2.8 7.4 0.1 2.6 2 0 0 2 2 2 0 Super-infection exclusion protein B Peptidase_C54 PF03416.19 EGC31168.1 - 2.6e-67 227.1 2.8 2.9e-66 223.7 2.8 2.1 1 1 0 1 1 1 1 Peptidase family C54 T2SSC PF11356.8 EGC31168.1 - 0.13 12.2 0.0 0.39 10.6 0.0 1.9 1 0 0 1 1 1 0 Type II secretion system protein C Rad60-SLD PF11976.8 EGC31169.1 - 9.4e-08 31.8 0.0 2.8e-07 30.3 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC31169.1 - 0.0004 20.1 0.0 0.0011 18.7 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Hydantoinase_B PF02538.14 EGC31170.1 - 4.1e-216 718.4 0.1 5.5e-216 718.0 0.1 1.2 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.18 EGC31170.1 - 8.9e-98 327.1 0.0 1.5e-97 326.4 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.13 EGC31170.1 - 9.1e-56 188.4 0.6 4.6e-54 182.8 0.0 2.6 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region ADK_lid PF05191.14 EGC31170.1 - 0.098 12.7 0.3 0.27 11.2 0.3 1.8 1 0 0 1 1 1 0 Adenylate kinase, active site lid Proteasome_A_N PF10584.9 EGC31170.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature FNIP PF05725.12 EGC31171.1 - 2.3e-41 139.7 45.8 6.9e-11 42.1 1.4 8.8 3 2 5 9 9 9 8 FNIP Repeat Spb1_C PF07780.12 EGC31172.1 - 2.5e-62 210.3 26.3 2.5e-62 210.3 26.3 4.4 3 2 1 4 4 4 1 Spb1 C-terminal domain FtsJ PF01728.19 EGC31172.1 - 1.9e-53 181.2 0.1 3.3e-53 180.4 0.1 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase DUF3381 PF11861.8 EGC31172.1 - 1.5e-35 122.4 18.6 1.5e-35 122.4 18.6 6.2 3 2 2 5 5 5 1 Domain of unknown function (DUF3381) DUF148 PF02520.17 EGC31172.1 - 0.011 15.9 3.7 0.011 15.9 3.7 3.6 3 1 0 3 3 3 0 Domain of unknown function DUF148 DUF3764 PF12594.8 EGC31172.1 - 0.015 15.3 1.2 1.5 8.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3764) MFS_1 PF07690.16 EGC31173.1 - 8.3e-15 54.6 34.3 8.3e-15 54.6 34.3 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGC31173.1 - 3e-06 26.8 20.2 3.8e-06 26.4 20.2 1.1 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB SAP18 PF06487.12 EGC31174.1 - 1.9e-30 105.9 0.1 2.4e-30 105.5 0.1 1.1 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Adeno_E3_CR2 PF02439.15 EGC31176.1 - 0.011 15.5 0.3 0.022 14.5 0.3 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Rieske PF00355.26 EGC31177.1 - 9.4e-13 47.9 0.0 1.8e-12 47.0 0.0 1.5 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.14 EGC31177.1 - 2.1e-09 37.8 0.0 3.5e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region OTU PF02338.19 EGC31179.1 - 2.2e-11 44.3 0.1 2.2e-11 44.3 0.1 2.2 2 0 0 2 2 1 1 OTU-like cysteine protease MMR1 PF08505.10 EGC31179.1 - 0.002 18.5 13.5 0.0034 17.7 13.5 1.5 1 0 0 1 1 1 1 Mitochondrial Myo2 receptor-related protein Mcm10 PF09332.11 EGC31179.1 - 0.016 14.7 12.9 0.025 14.0 12.9 1.4 1 0 0 1 1 1 0 Mcm10 replication factor Slu7 PF11708.8 EGC31179.1 - 0.027 14.3 13.1 0.043 13.6 13.1 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor Presenilin PF01080.17 EGC31179.1 - 0.055 12.2 11.9 0.067 12.0 11.9 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGC31179.1 - 0.21 10.6 9.7 0.27 10.2 9.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 EGC31179.1 - 0.36 10.9 9.3 0.69 10.0 9.3 1.4 1 0 0 1 1 1 0 Gti1/Pac2 family eIF-3_zeta PF05091.12 EGC31179.1 - 0.37 9.7 16.6 0.56 9.1 16.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) UPF0560 PF10577.9 EGC31179.1 - 0.53 8.7 21.6 0.75 8.2 21.6 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF3292 PF11696.8 EGC31179.1 - 0.78 8.0 14.1 1.1 7.6 14.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) EOS1 PF12326.8 EGC31179.1 - 0.83 9.6 4.2 0.48 10.3 2.5 1.5 2 0 0 2 2 1 0 N-glycosylation protein DUF853 PF05872.12 EGC31179.1 - 1.3 7.5 11.4 1.8 7.1 11.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Exonuc_VII_L PF02601.15 EGC31179.1 - 1.3 8.5 12.5 2.1 7.8 12.5 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit TERB2 PF15101.6 EGC31179.1 - 1.5 8.9 18.3 2.9 7.9 18.3 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 RR_TM4-6 PF06459.12 EGC31179.1 - 1.9 8.2 14.0 2.7 7.8 14.0 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF4637 PF15470.6 EGC31179.1 - 2 8.2 8.7 3.8 7.2 8.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Membralin PF09746.9 EGC31179.1 - 2.4 7.1 7.6 3.3 6.6 7.6 1.2 1 0 0 1 1 1 0 Tumour-associated protein DUF4175 PF13779.6 EGC31179.1 - 2.5 5.9 32.8 3.3 5.5 32.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FAM60A PF15396.6 EGC31179.1 - 2.7 7.9 9.1 4.9 7.1 9.1 1.4 1 0 0 1 1 1 0 Protein Family FAM60A CPSF100_C PF13299.6 EGC31179.1 - 4 7.6 11.6 6.9 6.8 11.6 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CLN3 PF02487.17 EGC31179.1 - 4.6 6.2 9.5 6.6 5.7 9.5 1.2 1 0 0 1 1 1 0 CLN3 protein FAM176 PF14851.6 EGC31179.1 - 4.7 6.9 6.0 8.6 6.0 6.0 1.4 1 0 0 1 1 1 0 FAM176 family SpoIIP PF07454.11 EGC31179.1 - 6.8 6.1 19.3 0.57 9.6 14.6 1.5 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) ALMT PF11744.8 EGC31179.1 - 6.8 5.4 9.5 9.8 4.9 9.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter V_ATPase_I PF01496.19 EGC31179.1 - 7 4.4 16.4 10 3.9 16.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Sec62 PF03839.16 EGC31179.1 - 9 5.7 10.0 14 5.1 10.0 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Band_3_cyto PF07565.13 EGC31179.1 - 9.1 6.0 14.6 17 5.1 13.9 1.7 2 0 0 2 2 2 0 Band 3 cytoplasmic domain GATA PF00320.27 EGC31180.1 - 1.2e-06 27.9 1.6 2.4e-06 27.0 1.6 1.5 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.12 EGC31180.1 - 0.038 13.5 0.5 0.095 12.2 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding Cript PF10235.9 EGC31180.1 - 0.077 13.6 1.9 0.11 13.1 1.8 1.5 1 1 0 1 1 1 0 Microtubule-associated protein CRIPT C1_2 PF03107.16 EGC31180.1 - 0.14 12.5 2.1 5.2 7.5 2.1 2.4 1 1 0 1 1 1 0 C1 domain zf-RanBP PF00641.18 EGC31180.1 - 0.14 11.5 2.9 3.2 7.2 0.2 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AT_hook PF02178.19 EGC31180.1 - 0.69 10.0 5.9 1.9 8.6 5.9 1.8 1 0 0 1 1 1 0 AT hook motif Thioredoxin PF00085.20 EGC31181.1 - 3.1e-05 23.9 0.1 5.2e-05 23.2 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGC31181.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.20 EGC31182.1 - 6.8e-12 45.3 0.0 9.1e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin SPATA9 PF15824.5 EGC31182.1 - 0.017 14.4 0.5 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 Spermatogenesis-associated protein 9 Thioredoxin_8 PF13905.6 EGC31182.1 - 0.026 14.9 2.1 0.069 13.5 0.0 2.4 1 1 1 2 2 2 0 Thioredoxin-like Thioredoxin_6 PF13848.6 EGC31182.1 - 0.038 13.9 1.8 1.1 9.2 0.1 2.1 1 1 1 2 2 2 0 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGC31182.1 - 0.11 12.9 0.0 0.17 12.3 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like domain Thioredoxin PF00085.20 EGC31183.1 - 3.5e-23 81.6 0.0 3.8e-23 81.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGC31183.1 - 1.2e-11 45.1 0.1 2.5e-11 44.0 0.1 1.5 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC31183.1 - 5.5e-07 29.8 0.0 3.1e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_3 PF13192.6 EGC31183.1 - 9.6e-06 25.6 0.0 1.2e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.6 EGC31183.1 - 2.5e-05 24.0 0.0 2.7e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGC31183.1 - 6.2e-05 23.1 0.0 9.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA PF00578.21 EGC31183.1 - 0.00013 21.8 0.0 0.00015 21.6 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.14 EGC31183.1 - 0.00018 21.9 0.0 0.00026 21.3 0.0 1.3 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Redoxin PF08534.10 EGC31183.1 - 0.016 14.9 0.0 0.018 14.7 0.0 1.2 1 0 0 1 1 1 0 Redoxin Glutaredoxin PF00462.24 EGC31183.1 - 0.021 15.0 0.0 0.035 14.3 0.0 1.4 1 0 0 1 1 1 0 Glutaredoxin Thioredoxin_6 PF13848.6 EGC31183.1 - 0.022 14.7 0.0 0.022 14.7 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain TraF PF13728.6 EGC31183.1 - 0.12 12.1 0.0 0.17 11.7 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Thioredoxin_4 PF13462.6 EGC31183.1 - 0.14 12.3 0.0 0.23 11.6 0.0 1.3 1 1 0 1 1 1 0 Thioredoxin KaiB PF07689.12 EGC31183.1 - 0.15 11.8 0.0 0.22 11.3 0.0 1.2 1 0 0 1 1 1 0 KaiB domain zf-C3HC4 PF00097.25 EGC31184.1 - 4.8e-12 45.6 8.2 7.9e-12 44.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31184.1 - 6e-12 45.2 8.6 9.1e-12 44.6 8.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC31184.1 - 2e-11 43.6 5.4 2.7e-11 43.1 5.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC31184.1 - 2.4e-10 40.2 8.3 3.8e-10 39.6 8.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC31184.1 - 4e-10 39.6 6.5 5.4e-10 39.1 3.2 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGC31184.1 - 5.6e-10 39.4 10.1 8.4e-10 38.8 10.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGC31184.1 - 5.7e-08 32.8 9.5 9e-08 32.2 9.5 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC31184.1 - 3.2e-06 26.9 8.3 5.3e-06 26.2 8.3 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC31184.1 - 4.4e-06 26.9 8.4 8.8e-06 25.9 8.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Nse PF11789.8 EGC31184.1 - 4.6e-05 23.1 4.1 8.2e-05 22.3 4.1 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-ANAPC11 PF12861.7 EGC31184.1 - 0.00025 21.1 3.7 0.0004 20.4 3.7 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.6 EGC31184.1 - 0.0014 18.7 3.6 0.0045 17.1 3.6 1.8 1 1 0 1 1 1 1 Zinc-binding RING-finger zf-RING_6 PF14835.6 EGC31184.1 - 0.0017 18.2 3.6 0.003 17.4 3.6 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.12 EGC31184.1 - 0.0047 16.3 1.1 0.0047 16.3 1.1 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger Baculo_IE-1 PF05290.11 EGC31184.1 - 0.0071 16.3 3.6 0.01 15.8 3.6 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Dicty_REP PF05086.12 EGC31184.1 - 0.014 13.4 3.7 0.018 13.1 3.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_4 PF14570.6 EGC31184.1 - 0.022 14.6 6.8 0.052 13.3 6.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.15 EGC31184.1 - 0.027 14.7 0.2 0.084 13.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain Zn_ribbon_17 PF17120.5 EGC31184.1 - 0.043 13.4 7.2 0.068 12.8 7.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4064 PF13273.6 EGC31184.1 - 0.054 13.8 0.8 0.12 12.7 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) zf-P11 PF03854.14 EGC31184.1 - 0.15 11.7 5.5 0.27 10.9 5.5 1.4 1 0 0 1 1 1 0 P-11 zinc finger zf-RING_11 PF17123.5 EGC31184.1 - 0.3 10.9 10.5 0.2 11.4 6.4 2.3 2 0 0 2 2 2 0 RING-like zinc finger DUF3439 PF11921.8 EGC31184.1 - 0.72 9.8 10.3 1.3 9.0 10.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_10 PF16685.5 EGC31184.1 - 0.72 10.0 5.0 1.2 9.3 5.0 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 V-SNARE_C PF12352.8 EGC31186.1 - 1.4e-07 31.7 2.6 1.4e-07 31.7 2.6 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus DUF5089 PF17002.5 EGC31186.1 - 2e-05 24.6 6.7 4.1e-05 23.5 6.7 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF5089) Sec20 PF03908.13 EGC31186.1 - 0.011 15.6 2.5 0.011 15.6 2.5 2.2 2 1 1 3 3 3 0 Sec20 MCPsignal PF00015.21 EGC31186.1 - 0.016 15.0 1.1 0.016 15.0 1.1 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Hrs_helical PF12210.8 EGC31186.1 - 0.042 14.4 8.8 0.26 11.8 0.1 2.8 1 1 2 3 3 3 0 Hepatocyte growth factor-regulated tyrosine kinase substrate TUSC2 PF15000.6 EGC31186.1 - 0.068 13.5 1.2 0.11 12.8 0.3 1.7 1 1 1 2 2 2 0 Tumour suppressor candidate 2 B2 PF11473.8 EGC31186.1 - 0.15 11.9 1.2 0.42 10.5 0.4 2.1 2 0 0 2 2 2 0 RNA binding protein B2 DUF573 PF04504.14 EGC31186.1 - 0.81 10.4 10.7 2.2 9.0 1.4 3.1 1 1 2 3 3 3 0 Protein of unknown function, DUF573 Allexi_40kDa PF05549.11 EGC31186.1 - 0.85 9.1 12.3 2.3 7.7 4.5 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DASH_Dad1 PF08649.10 EGC31186.1 - 1.7 8.9 7.6 5.4 7.3 0.9 3.0 3 0 0 3 3 3 0 DASH complex subunit Dad1 Lectin_N PF03954.14 EGC31186.1 - 1.7 8.4 5.7 1.1 9.0 2.4 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 EGC31186.1 - 2.9 7.9 15.8 11 6.0 3.0 3.3 1 1 2 3 3 3 0 Laminin Domain II DUF948 PF06103.11 EGC31186.1 - 3.3 8.0 8.5 25 5.2 0.0 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF1664 PF07889.12 EGC31186.1 - 5.9 6.9 8.6 15 5.7 3.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Cytochrom_C PF00034.21 EGC31188.1 - 1.6e-12 48.4 0.0 2.1e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.6 EGC31188.1 - 5.7e-08 33.0 1.1 1.5e-07 31.7 1.1 1.6 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.6 EGC31188.1 - 0.012 15.3 1.1 0.025 14.3 1.1 1.9 1 1 0 1 1 1 0 Cytochrome c-550 domain Peptidase_S9 PF00326.21 EGC31189.1 - 3.4e-05 23.4 0.0 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC31189.1 - 0.0017 17.7 0.1 1 8.6 0.1 2.3 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC31189.1 - 0.0045 17.6 0.0 0.0081 16.8 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGC31189.1 - 0.046 13.4 0.2 0.13 11.9 0.2 1.7 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGC31189.1 - 0.056 13.2 0.1 0.14 11.9 0.1 1.6 1 0 0 1 1 1 0 PGAP1-like protein Acetyltransf_7 PF13508.7 EGC31189.1 - 0.082 13.4 0.0 0.22 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Myb_DNA-binding PF00249.31 EGC31190.1 - 7.1e-05 22.9 0.1 0.00016 21.8 0.1 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain THRAP3_BCLAF1 PF15440.6 EGC31192.1 - 0.17 10.9 40.2 0.22 10.5 40.2 1.1 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF3439 PF11921.8 EGC31192.1 - 9.3 6.2 9.7 7.5 6.5 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) DUF3439 PF11921.8 EGC31193.1 - 0.088 12.8 0.9 0.24 11.4 0.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC31193.1 - 4.4 7.3 10.4 8.2 6.4 10.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Metallophos PF00149.28 EGC31194.1 - 6.7e-10 39.8 2.6 1e-09 39.2 2.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Statherin PF03875.13 EGC31194.1 - 0.027 14.5 0.1 3 8.0 0.0 2.5 2 0 0 2 2 2 0 Statherin SHOCT PF09851.9 EGC31194.1 - 0.097 12.4 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Short C-terminal domain Acyltransferase PF01553.21 EGC31195.1 - 3.1e-06 26.9 0.0 3e-05 23.6 0.0 2.4 2 1 0 2 2 2 1 Acyltransferase Adeno_E3_CR2 PF02439.15 EGC31195.1 - 0.77 9.6 4.2 1.5 8.7 4.2 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ADH_zinc_N PF00107.26 EGC31196.1 - 6e-14 52.1 0.0 1.5e-13 50.9 0.0 1.6 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC31196.1 - 4.6e-06 27.7 0.0 8.2e-06 26.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC31196.1 - 9.5e-06 25.5 0.1 2.3e-05 24.2 0.0 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain FliMN_C PF01052.20 EGC31196.1 - 0.018 15.1 0.1 0.057 13.4 0.0 1.9 2 0 0 2 2 2 0 Type III flagellar switch regulator (C-ring) FliN C-term ADH_N_2 PF16884.5 EGC31196.1 - 0.13 12.1 0.1 0.46 10.4 0.0 1.9 2 0 0 2 2 2 0 N-terminal domain of oxidoreductase PFO_beta_C PF12367.8 EGC31196.1 - 0.2 11.8 0.0 0.57 10.4 0.0 1.8 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal PKcGMP_CC PF16808.5 EGC31197.1 - 0.012 15.5 3.2 0.014 15.2 0.0 2.5 2 0 0 2 2 2 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Bax1-I PF01027.20 EGC31200.1 - 1.1e-06 28.7 10.0 3.6e-06 27.0 10.0 1.8 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Bax1-I PF01027.20 EGC31201.1 - 2.9e-20 73.0 7.7 4.1e-20 72.5 7.7 1.2 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Phage_holin_Dp1 PF16938.5 EGC31201.1 - 0.2 11.9 0.1 0.2 11.9 0.1 2.3 3 0 0 3 3 3 0 Putative phage holin Dp-1 DUF4229 PF14012.6 EGC31201.1 - 0.83 9.8 3.7 7.3 6.8 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4229) CorA PF01544.18 EGC31202.1 - 0.0016 17.8 0.8 0.0019 17.6 0.8 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein bZIP_1 PF00170.21 EGC31202.1 - 0.0028 17.7 9.9 0.026 14.6 2.8 2.2 2 0 0 2 2 2 1 bZIP transcription factor TelA PF05816.11 EGC31202.1 - 0.0034 16.5 4.1 0.0035 16.4 4.1 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) FlaC_arch PF05377.11 EGC31202.1 - 0.0041 17.5 8.7 0.02 15.3 1.8 2.1 1 1 1 2 2 2 1 Flagella accessory protein C (FlaC) DUF16 PF01519.16 EGC31202.1 - 0.0041 17.6 9.4 0.082 13.4 0.9 2.0 1 1 1 2 2 2 2 Protein of unknown function DUF16 Cep57_MT_bd PF06657.13 EGC31202.1 - 0.0041 17.5 6.3 0.026 14.9 5.6 2.2 1 1 0 1 1 1 1 Centrosome microtubule-binding domain of Cep57 DUF4407 PF14362.6 EGC31202.1 - 0.02 14.3 1.3 0.022 14.1 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) BNIP2 PF12496.8 EGC31202.1 - 0.021 15.2 0.8 0.024 15.1 0.8 1.1 1 0 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 Spc7 PF08317.11 EGC31202.1 - 0.027 13.3 6.7 0.028 13.3 6.7 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein RPW8 PF05659.11 EGC31202.1 - 0.028 14.1 3.1 0.045 13.4 3.1 1.4 1 1 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 HALZ PF02183.18 EGC31202.1 - 0.037 14.2 6.1 0.16 12.2 2.1 2.4 2 0 0 2 2 2 0 Homeobox associated leucine zipper IFT20 PF14931.6 EGC31202.1 - 0.041 14.0 2.1 0.041 14.0 2.1 2.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 TSC22 PF01166.18 EGC31202.1 - 0.044 14.1 8.2 0.33 11.3 0.8 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family DUF848 PF05852.11 EGC31202.1 - 0.045 13.9 5.3 1 9.5 0.5 2.0 1 1 1 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF603 PF04645.12 EGC31202.1 - 0.052 13.3 4.1 2.1 8.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF603 Phage_GP20 PF06810.11 EGC31202.1 - 0.053 13.3 6.1 0.064 13.1 6.1 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.15 EGC31202.1 - 0.061 13.1 9.5 0.54 10.1 2.1 2.2 1 1 1 2 2 2 0 Septum formation initiator HMMR_N PF15905.5 EGC31202.1 - 0.064 12.7 8.5 0.064 12.7 8.5 1.1 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Atg14 PF10186.9 EGC31202.1 - 0.083 12.0 6.3 0.091 11.8 6.3 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Swi5 PF07061.11 EGC31202.1 - 0.083 13.0 5.2 2.5 8.2 2.1 2.2 1 1 1 2 2 2 0 Swi5 Prefoldin PF02996.17 EGC31202.1 - 0.085 12.8 0.8 0.085 12.8 0.8 2.1 1 1 1 2 2 2 0 Prefoldin subunit TMF_DNA_bd PF12329.8 EGC31202.1 - 0.086 12.9 10.8 0.55 10.3 1.5 2.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1664 PF07889.12 EGC31202.1 - 0.1 12.6 5.3 0.14 12.2 5.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) HIP1_clath_bdg PF16515.5 EGC31202.1 - 0.11 13.1 7.5 0.28 11.8 7.5 1.6 1 1 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 CHASE9 PF17153.4 EGC31202.1 - 0.11 12.6 2.4 4.4 7.5 1.8 2.1 1 1 1 2 2 2 0 Periplasmic sensor domain, extracellular PspA_IM30 PF04012.12 EGC31202.1 - 0.13 11.8 4.3 0.58 9.7 0.5 1.9 1 1 0 1 1 1 0 PspA/IM30 family Mt_ATP_synt PF15704.5 EGC31202.1 - 0.14 12.1 4.2 0.19 11.6 4.2 1.2 1 0 0 1 1 1 0 Mitochondrial ATP synthase subunit YabA PF06156.13 EGC31202.1 - 0.23 12.1 5.3 0.33 11.6 5.3 1.4 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EGC31202.1 - 0.26 11.8 10.7 40 4.8 10.7 2.2 1 1 0 1 1 1 0 Cell division protein ZapB BRE1 PF08647.11 EGC31202.1 - 0.26 11.4 10.9 6.1 7.0 10.9 2.1 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase Fzo_mitofusin PF04799.13 EGC31202.1 - 0.27 10.8 2.8 0.38 10.3 2.8 1.4 1 1 0 1 1 1 0 fzo-like conserved region TMCO5 PF14992.6 EGC31202.1 - 0.27 10.8 7.9 0.29 10.7 7.9 1.1 1 0 0 1 1 1 0 TMCO5 family DUF812 PF05667.11 EGC31202.1 - 0.27 10.1 7.9 0.27 10.1 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Vps51 PF08700.11 EGC31202.1 - 0.27 11.3 4.2 2.8 8.1 0.2 2.7 2 2 0 2 2 2 0 Vps51/Vps67 DUF5320 PF17253.2 EGC31202.1 - 0.28 12.3 1.1 0.28 12.3 1.1 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5320) DUF2205 PF10224.9 EGC31202.1 - 0.34 10.9 7.8 1.2 9.1 5.7 2.1 1 1 1 2 2 2 0 Short coiled-coil protein DUF1640 PF07798.11 EGC31202.1 - 0.39 10.8 5.8 0.91 9.6 5.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Cnn_1N PF07989.11 EGC31202.1 - 0.42 10.8 10.7 0.61 10.3 2.7 2.2 1 1 1 2 2 2 0 Centrosomin N-terminal motif 1 KASH_CCD PF14662.6 EGC31202.1 - 0.45 10.3 11.3 0.79 9.5 11.3 1.5 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 or KASH Herpes_UL14 PF03580.14 EGC31202.1 - 0.5 10.6 4.0 0.57 10.4 1.0 1.9 1 1 1 2 2 2 0 Herpesvirus UL14-like protein PRKG1_interact PF15898.5 EGC31202.1 - 0.5 11.3 8.7 0.71 10.8 8.7 1.3 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain DUF4795 PF16043.5 EGC31202.1 - 0.5 9.9 10.4 0.83 9.2 2.6 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4795) ACCA PF03255.14 EGC31202.1 - 0.62 9.9 5.1 0.31 10.9 2.2 1.8 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF3450 PF11932.8 EGC31202.1 - 0.7 9.1 5.4 3.3 7.0 4.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) Seryl_tRNA_N PF02403.22 EGC31202.1 - 0.71 10.1 8.7 1.8 8.8 1.6 1.9 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain GrpE PF01025.19 EGC31202.1 - 0.76 9.4 6.3 1.3 8.7 6.0 1.4 1 1 0 1 1 1 0 GrpE Macoilin PF09726.9 EGC31202.1 - 1.2 7.6 7.0 1.4 7.4 7.0 1.0 1 0 0 1 1 1 0 Macoilin family GTP-bdg_M PF16360.5 EGC31202.1 - 4.5 7.9 6.2 17 6.1 1.6 2.1 1 1 1 2 2 2 0 GTP-binding GTPase Middle Region TLE_N PF03920.15 EGC31202.1 - 6.5 6.9 8.7 1e+02 3.0 6.1 2.5 1 1 0 1 1 1 0 Groucho/TLE N-terminal Q-rich domain zf-C3HC4_3 PF13920.6 EGC31203.1 - 5.2e-09 35.8 8.1 8.9e-09 35.1 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC31203.1 - 0.00042 20.6 12.0 0.00077 19.7 12.0 1.5 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 EGC31203.1 - 0.00096 19.3 23.4 0.0017 18.4 23.4 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Prok-RING_4 PF14447.6 EGC31203.1 - 0.0027 17.6 9.4 0.0049 16.7 9.4 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC31203.1 - 0.0046 16.8 13.5 0.0098 15.7 13.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.28 EGC31203.1 - 0.033 14.3 0.3 0.26 11.4 0.0 2.4 2 0 0 2 2 2 0 SPRY domain zf-C3HC4_2 PF13923.6 EGC31203.1 - 0.16 11.8 12.4 0.29 11.0 12.4 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) MRNIP PF15749.5 EGC31203.1 - 0.29 11.9 24.4 1.3 9.8 7.5 2.6 2 0 0 2 2 2 0 MRN-interacting protein DUF2722 PF10846.8 EGC31203.1 - 0.77 8.6 35.6 1.3 7.9 21.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) zf-RING_5 PF14634.6 EGC31203.1 - 1.1 9.2 11.7 2.4 8.2 11.7 1.6 1 0 0 1 1 1 0 zinc-RING finger domain HNOBA PF07701.14 EGC31203.1 - 1.3 8.4 13.3 0.038 13.4 2.3 2.4 2 0 0 2 2 2 0 Heme NO binding associated Connexin PF00029.19 EGC31203.1 - 1.4 8.6 10.4 2.5 7.8 1.0 3.3 3 0 0 3 3 3 0 Connexin FAM176 PF14851.6 EGC31203.1 - 2.1 8.0 11.7 6.1 6.5 1.4 2.4 2 0 0 2 2 2 0 FAM176 family zf-C3HC4_4 PF15227.6 EGC31203.1 - 6.4 7.0 10.3 14 5.9 10.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF4820 PF16091.5 EGC31203.1 - 8.8 5.6 19.1 4.4 6.6 4.7 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) Glyco_hydro_9 PF00759.19 EGC31204.1 - 2.2e-119 399.6 25.0 2.6e-119 399.3 25.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ribosomal_S19 PF00203.21 EGC31205.1 - 1.7e-30 104.7 1.0 2.3e-30 104.3 1.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S19 CBM49 PF09478.10 EGC31206.1 - 9.4e-15 54.7 0.2 1.3e-14 54.3 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 FOLN PF09289.10 EGC31206.1 - 0.013 15.6 0.8 0.013 15.6 0.8 2.0 2 0 0 2 2 2 0 Follistatin/Osteonectin-like EGF domain CBM_2 PF00553.19 EGC31206.1 - 0.077 13.3 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Cellulose binding domain FH2 PF02181.23 EGC31207.1 - 1e-93 314.4 5.4 1e-93 314.4 5.4 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGC31207.1 - 7.9e-29 100.6 3.4 2.9e-28 98.7 1.0 2.6 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGC31207.1 - 4.2e-25 88.5 4.5 4.2e-25 88.5 4.5 2.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain AcylCoA_dehyd_C PF12186.8 EGC31207.1 - 0.33 11.1 2.0 0.61 10.2 0.1 2.5 3 0 0 3 3 3 0 Acyl-CoA dehydrogenase C terminal GST_C_3 PF14497.6 EGC31208.1 - 0.04 14.1 1.8 0.43 10.8 0.3 3.0 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Pex19 PF04614.12 EGC31209.1 - 0.68 9.7 6.3 0.95 9.2 2.7 2.2 2 0 0 2 2 2 0 Pex19 protein family DUF4890 PF16231.5 EGC31209.1 - 3.2 8.3 6.1 1.6 9.3 2.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4890) PEPcase_2 PF14010.6 EGC31212.1 - 0.0062 15.1 4.1 0.0086 14.6 4.1 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HD_3 PF13023.6 EGC31212.1 - 0.015 15.2 4.1 0.019 14.9 3.5 1.4 1 1 0 1 1 1 0 HD domain RasGAP_C PF03836.15 EGC31212.1 - 8.7 6.5 21.6 84 3.3 21.6 2.1 1 1 0 1 1 1 0 RasGAP C-terminus Actin PF00022.19 EGC31214.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin PIP5K PF01504.18 EGC31217.1 - 2.6e-34 118.7 0.3 3.9e-31 108.3 0.1 6.3 5 3 1 6 6 6 2 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.24 EGC31217.1 - 7e-25 87.6 0.1 9.6e-24 83.9 0.1 2.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1003 PF06210.11 EGC31217.1 - 7.4 6.7 9.0 2.8 8.1 1.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1003) Arf PF00025.21 EGC31218.1 - 5.5e-70 234.4 0.2 6.7e-70 234.1 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGC31218.1 - 6.9e-14 51.8 0.0 8.8e-14 51.4 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC31218.1 - 2.6e-13 49.8 0.0 3.2e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGC31218.1 - 1.2e-12 48.1 0.0 1.7e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGC31218.1 - 5.2e-11 42.3 2.3 1.5e-07 30.9 0.3 2.4 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC31218.1 - 1.1e-06 28.2 0.0 1.3e-06 28.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC31218.1 - 0.00017 21.6 0.0 0.00028 21.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase MeaB PF03308.16 EGC31218.1 - 0.058 12.4 0.0 0.16 11.0 0.0 1.6 2 1 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ras PF00071.22 EGC31219.1 - 5.4e-65 217.9 0.4 6.3e-65 217.7 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31219.1 - 1.9e-36 124.9 0.4 3.9e-36 123.9 0.1 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31219.1 - 8.9e-16 57.8 0.1 1.1e-15 57.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC31219.1 - 2.3e-06 27.1 0.1 2.8e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC31219.1 - 1.2e-05 25.3 0.4 0.14 12.1 0.0 2.3 1 1 1 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC31219.1 - 2.8e-05 23.7 0.4 6.6e-05 22.5 0.2 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC31219.1 - 5.1e-05 23.3 0.0 0.00018 21.6 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC31219.1 - 0.0011 18.4 0.1 0.0016 17.9 0.1 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC31219.1 - 0.0016 17.6 1.4 0.029 13.5 0.1 2.6 1 1 1 2 2 2 1 G-protein alpha subunit AAA PF00004.29 EGC31219.1 - 0.0075 16.7 0.0 0.35 11.3 0.0 2.1 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGC31219.1 - 0.036 13.8 0.0 0.16 11.7 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC31219.1 - 0.061 13.7 0.0 0.098 13.0 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGC31219.1 - 0.068 13.4 0.0 0.13 12.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGC31219.1 - 0.077 12.5 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGC31219.1 - 0.098 12.4 0.2 0.79 9.5 0.0 2.1 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.14 EGC31219.1 - 0.098 12.7 0.0 0.11 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) TniB PF05621.11 EGC31219.1 - 0.14 11.5 0.0 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein DUF3246 PF11596.8 EGC31220.1 - 0.0077 15.7 1.3 0.011 15.2 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3246) Spem1 PF15670.5 EGC31220.1 - 0.084 12.4 9.4 0.13 11.8 9.4 1.3 1 0 0 1 1 1 0 Spermatid maturation protein 1 CENP-B_dimeris PF09026.10 EGC31220.1 - 0.59 10.6 10.0 0.043 14.2 4.8 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain NOA36 PF06524.12 EGC31220.1 - 0.66 9.2 18.9 0.97 8.7 18.9 1.2 1 0 0 1 1 1 0 NOA36 protein Membralin PF09746.9 EGC31220.1 - 0.83 8.6 11.0 1.1 8.3 11.0 1.2 1 0 0 1 1 1 0 Tumour-associated protein Utp14 PF04615.13 EGC31220.1 - 1.3 7.6 24.7 1.6 7.2 24.7 1.1 1 0 0 1 1 1 0 Utp14 protein CNDH2_C PF16858.5 EGC31220.1 - 1.4 8.8 21.2 2.1 8.2 21.2 1.3 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term FAM60A PF15396.6 EGC31220.1 - 1.4 8.8 11.2 2.3 8.2 11.2 1.5 1 0 0 1 1 1 0 Protein Family FAM60A DUF4175 PF13779.6 EGC31220.1 - 2.1 6.1 19.2 2.3 6.0 19.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CCSAP PF15748.5 EGC31220.1 - 2.2 8.4 14.8 3 7.9 14.8 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated DivIC PF04977.15 EGC31220.1 - 3.1 7.6 20.1 9.3 6.1 20.1 1.9 1 0 0 1 1 1 0 Septum formation initiator Cwf_Cwc_15 PF04889.12 EGC31220.1 - 7.1 6.3 30.7 11 5.6 30.7 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein BSP_II PF05432.11 EGC31220.1 - 9.3 5.8 14.3 14 5.3 14.3 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) Herpes_UL32 PF06070.11 EGC31220.1 - 9.6 3.8 17.2 13 3.4 17.2 1.1 1 0 0 1 1 1 0 Herpesvirus large structural phosphoprotein UL32 SAC3_GANP PF03399.16 EGC31221.1 - 6.6e-24 84.8 3.0 6.6e-24 84.8 3.0 3.2 2 1 0 2 2 2 1 SAC3/GANP family LapA_dom PF06305.11 EGC31222.1 - 0.12 12.2 1.7 1.1 9.1 1.7 2.6 1 1 0 1 1 1 0 Lipopolysaccharide assembly protein A domain TssO PF17561.2 EGC31224.1 - 0.073 13.2 5.5 0.08 13.0 5.5 1.0 1 0 0 1 1 1 0 Type VI secretion system, TssO Spectrin PF00435.21 EGC31224.1 - 0.083 13.4 5.3 0.087 13.3 5.3 1.1 1 0 0 1 1 1 0 Spectrin repeat MMPL PF03176.15 EGC31224.1 - 0.75 8.7 1.7 0.7 8.8 1.7 1.0 1 0 0 1 1 1 0 MMPL family UBA_6 PF18039.1 EGC31224.1 - 5.7 6.9 8.8 15 5.6 0.1 3.2 2 1 2 4 4 4 0 UBA-like domain FNIP PF05725.12 EGC31226.1 - 5.6e-58 192.9 98.4 3.5e-12 46.3 0.7 15.8 9 4 7 16 16 16 13 FNIP Repeat FSA_C PF10479.9 EGC31226.1 - 0.34 9.0 6.1 0.5 8.4 6.1 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus DUF3439 PF11921.8 EGC31226.1 - 0.68 9.9 9.5 1.6 8.7 9.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF1685 PF07939.11 EGC31226.1 - 3.4 7.5 5.7 8 6.3 0.0 3.4 3 2 1 4 4 4 0 Protein of unknown function (DUF1685) SSP160 PF06933.11 EGC31226.1 - 4.3 5.4 16.7 5.9 5.0 16.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_2 PF07719.17 EGC31227.1 - 8.6e-46 150.4 35.9 7.7e-06 25.6 0.1 17.0 19 0 0 19 19 16 11 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31227.1 - 4.7e-44 148.8 10.0 2.9e-07 30.9 0.0 11.6 8 2 3 12 12 12 10 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31227.1 - 1.5e-37 125.1 0.0 0.01 16.6 0.0 12.9 8 4 6 14 14 12 9 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31227.1 - 8e-35 117.3 46.8 3.3e-07 29.8 0.1 16.6 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31227.1 - 3.8e-34 114.0 37.1 7.2e-06 25.8 0.0 16.8 19 0 0 19 19 18 8 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31227.1 - 1e-30 104.3 9.6 0.0023 18.5 0.1 12.4 14 0 0 14 14 12 6 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31227.1 - 3.5e-27 94.8 0.0 1.7e-05 25.3 0.0 9.1 6 4 4 11 11 11 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31227.1 - 3.5e-26 91.3 31.1 4.8e-05 23.6 0.0 12.0 8 3 5 13 13 12 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31227.1 - 1.4e-25 87.4 9.2 0.0092 16.0 0.0 13.5 15 0 0 15 15 15 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31227.1 - 1.8e-25 87.4 36.8 0.00047 20.3 0.2 15.0 15 2 2 17 17 14 7 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC31227.1 - 3e-17 63.0 0.5 0.0018 17.7 0.0 5.7 1 1 3 5 5 5 4 MalT-like TPR region TPR_11 PF13414.6 EGC31227.1 - 2.2e-16 59.2 42.1 0.0014 18.3 0.0 12.2 11 3 3 14 14 14 6 TPR repeat ANAPC3 PF12895.7 EGC31227.1 - 4.7e-13 49.2 24.5 0.012 15.9 0.3 8.2 4 3 5 9 9 9 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.6 EGC31227.1 - 2.2e-10 40.1 29.1 0.54 10.2 0.0 13.6 16 0 0 16 16 14 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC31227.1 - 5.5e-09 36.0 0.0 0.097 12.8 0.0 6.2 6 0 0 6 6 6 1 Tetratricopeptide repeat ChAPs PF09295.10 EGC31227.1 - 1.2e-07 31.1 0.4 1.2e-07 31.1 0.4 2.6 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) NARP1 PF12569.8 EGC31227.1 - 1.5e-06 27.5 0.7 1.3e-05 24.3 0.1 6.9 6 2 2 8 8 6 3 NMDA receptor-regulated protein 1 TPR_20 PF14561.6 EGC31227.1 - 1.6e-06 28.3 0.5 0.28 11.5 0.1 6.4 7 1 1 8 8 5 1 Tetratricopeptide repeat HrpB1_HrpK PF09613.10 EGC31227.1 - 3.9e-05 23.3 0.0 0.2 11.3 0.0 4.2 3 1 0 4 4 4 1 Bacterial type III secretion protein (HrpB1_HrpK) TPR_3 PF07720.12 EGC31227.1 - 0.00076 19.4 9.5 0.035 14.1 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPPII_N PF12583.8 EGC31227.1 - 0.063 13.9 3.7 2.2 8.8 0.0 4.9 6 0 0 6 6 6 0 Tripeptidyl peptidase II N terminal Fis1_TPR_C PF14853.6 EGC31227.1 - 0.29 11.2 6.8 7.9 6.6 0.0 4.9 6 0 0 6 6 4 0 Fis1 C-terminal tetratricopeptide repeat AAA_31 PF13614.6 EGC31228.1 - 2.1e-22 79.9 0.0 3.5e-22 79.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain CbiA PF01656.23 EGC31228.1 - 1.8e-19 70.0 0.0 2.9e-19 69.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ParA PF10609.9 EGC31228.1 - 2.8e-19 69.6 0.4 1.7e-18 67.0 0.4 1.9 1 1 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase MipZ PF09140.11 EGC31228.1 - 5.8e-11 42.2 0.0 9.3e-11 41.5 0.0 1.3 1 0 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGC31228.1 - 1e-07 31.5 2.7 1.8e-07 30.6 2.7 1.6 1 1 0 1 1 1 1 Anion-transporting ATPase CBP_BcsQ PF06564.12 EGC31228.1 - 7.5e-07 28.9 0.0 1.6e-06 27.8 0.0 1.5 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGC31228.1 - 3.3e-06 26.7 0.3 0.017 14.6 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_26 PF13500.6 EGC31228.1 - 0.00018 21.4 1.8 0.22 11.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain SRP54 PF00448.22 EGC31228.1 - 0.0002 21.1 0.9 0.03 13.9 0.6 2.4 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_24 PF13479.6 EGC31228.1 - 0.00023 20.9 0.0 0.00038 20.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGC31228.1 - 0.064 13.0 0.0 0.13 12.0 0.0 1.5 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NACHT PF05729.12 EGC31228.1 - 0.16 11.9 0.1 0.31 10.9 0.1 1.5 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EGC31228.1 - 0.2 10.8 0.3 0.37 9.9 0.3 1.3 1 0 0 1 1 1 0 NB-ARC domain TPR_1 PF00515.28 EGC31229.1 - 1.2e-35 119.8 12.7 1.6e-06 27.7 0.1 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31229.1 - 5.1e-34 113.6 4.0 5.4e-05 23.0 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31229.1 - 3.3e-26 89.3 14.5 0.0008 19.4 0.0 8.1 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31229.1 - 6.4e-23 80.8 1.0 1e-05 25.7 0.0 5.7 3 1 1 5 5 5 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31229.1 - 2.2e-22 78.4 11.6 8.8e-06 25.3 0.0 7.3 5 2 2 7 7 7 5 TPR repeat TPR_19 PF14559.6 EGC31229.1 - 1.3e-21 76.9 0.3 0.00012 22.6 0.0 5.4 3 2 2 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31229.1 - 4.2e-20 70.7 0.0 0.095 13.6 0.1 7.7 4 3 4 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31229.1 - 3.5e-17 61.5 3.2 0.0013 19.0 0.1 6.1 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31229.1 - 1.6e-16 60.7 0.0 0.042 14.5 0.0 6.4 5 2 2 7 7 7 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31229.1 - 1.1e-15 56.4 0.2 0.23 11.6 0.0 7.4 7 0 0 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31229.1 - 6.3e-12 45.6 8.3 0.0011 19.1 0.4 4.7 2 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC31229.1 - 1.7e-09 37.7 2.8 2 9.2 0.0 7.4 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC31229.1 - 4.3e-08 32.8 0.2 10 6.1 0.0 7.2 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC31229.1 - 2.2e-07 30.6 0.0 0.4 10.0 0.0 4.2 2 2 2 4 4 4 2 MalT-like TPR region PPR PF01535.20 EGC31229.1 - 2.8e-05 24.0 0.3 0.97 9.8 0.0 5.6 7 0 0 7 7 5 1 PPR repeat TPR_9 PF13371.6 EGC31229.1 - 0.00022 21.3 0.0 1.8 8.8 0.0 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_21 PF09976.9 EGC31229.1 - 0.0011 18.7 0.3 0.12 12.0 0.0 3.3 3 1 0 4 4 4 1 Tetratricopeptide repeat-like domain TPR_15 PF13429.6 EGC31229.1 - 0.0033 16.7 0.0 0.27 10.4 0.0 3.3 2 1 0 2 2 2 1 Tetratricopeptide repeat DUF5113 PF17140.4 EGC31229.1 - 0.004 17.0 6.5 2.1 8.1 0.2 4.4 3 2 3 6 6 5 1 Domain of unknown function (DUF5113) NARP1 PF12569.8 EGC31229.1 - 0.0097 14.9 3.6 1.1 8.1 0.2 3.4 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 MIT PF04212.18 EGC31229.1 - 0.04 14.0 13.4 0.26 11.4 1.0 5.7 4 2 1 6 6 6 0 MIT (microtubule interacting and transport) domain SHNi-TPR PF10516.9 EGC31229.1 - 0.061 12.8 0.0 0.82 9.2 0.0 3.0 4 0 0 4 4 4 0 SHNi-TPR SNAP PF14938.6 EGC31229.1 - 0.077 12.4 3.8 0.72 9.2 0.4 3.3 4 1 0 4 4 4 0 Soluble NSF attachment protein, SNAP SRP_TPR_like PF17004.5 EGC31229.1 - 0.078 13.0 0.1 0.078 13.0 0.1 2.3 2 0 0 2 2 2 0 Putative TPR-like repeat Turandot PF07240.11 EGC31229.1 - 0.11 12.5 0.8 8.2 6.5 0.0 3.7 3 1 1 4 4 4 0 Stress-inducible humoral factor Turandot WD40 PF00400.32 EGC31231.1 - 4.1e-57 188.8 18.6 1.6e-09 38.2 0.5 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC31231.1 - 8.7e-15 54.8 0.5 0.0037 17.5 0.0 4.9 1 1 4 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC31231.1 - 8.9e-07 27.9 4.5 1.6 7.3 0.0 4.3 2 2 2 4 4 4 4 Nucleoporin Nup120/160 eIF2A PF08662.11 EGC31231.1 - 0.00019 21.4 0.2 0.037 13.9 0.1 2.8 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGC31231.1 - 0.00021 20.7 0.0 0.12 11.7 0.0 2.8 2 1 0 3 3 3 2 WD40-like domain IKI3 PF04762.12 EGC31231.1 - 0.011 13.8 0.0 0.21 9.6 0.0 2.5 2 1 0 2 2 2 0 IKI3 family Cytochrom_D1 PF02239.16 EGC31231.1 - 0.013 14.1 0.1 2.7 6.4 0.1 2.9 2 1 1 3 3 3 0 Cytochrome D1 heme domain LssY_C PF14067.6 EGC31231.1 - 0.058 12.9 0.5 2.1 7.8 0.0 2.6 2 1 1 3 3 3 0 LssY C-terminus PD40 PF07676.12 EGC31231.1 - 0.067 13.2 0.2 26 4.9 0.0 4.3 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat GlcNAc PF11397.8 EGC31232.1 - 1.1e-74 252.0 0.1 2.3e-62 211.5 0.1 2.2 1 1 1 2 2 2 2 Glycosyltransferase (GlcNAc) PKcGMP_CC PF16808.5 EGC31233.1 - 0.0029 17.4 2.9 0.0067 16.3 2.9 1.5 1 0 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase Herpes_UL14 PF03580.14 EGC31233.1 - 1.1 9.5 6.2 1.9 8.7 6.2 1.3 1 0 0 1 1 1 0 Herpesvirus UL14-like protein Striatin PF08232.12 EGC31233.1 - 5.9 7.5 14.3 0.88 10.2 9.4 1.9 2 0 0 2 2 2 0 Striatin family LMBR1 PF04791.16 EGC31233.1 - 6.1 5.6 8.8 7.8 5.3 8.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Zip PF02535.22 EGC31233.1 - 8.1 5.6 6.1 13 4.9 6.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TPR_2 PF07719.17 EGC31234.1 - 0.0096 16.0 1.3 0.41 10.9 0.1 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31234.1 - 0.011 15.7 0.7 0.32 11.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31234.1 - 0.069 13.5 0.1 0.83 10.0 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31234.1 - 0.13 12.1 3.5 0.27 11.1 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31234.1 - 0.22 11.8 6.1 1.3 9.4 0.2 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat LRR_6 PF13516.6 EGC31234.1 - 2 8.7 29.0 0.89 9.8 0.9 7.6 7 0 0 7 7 7 0 Leucine Rich repeat Orthoreo_P10 PF07204.11 EGC31235.1 - 0.1 12.6 0.4 0.22 11.5 0.4 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 XET_C PF06955.12 EGC31236.1 - 0.14 12.1 0.3 0.35 10.7 0.3 1.8 1 1 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus RhoGAP PF00620.27 EGC31237.1 - 1.1e-33 116.2 0.4 1.1e-33 116.2 0.4 3.0 3 0 0 3 3 3 1 RhoGAP domain DUF2201_N PF13203.6 EGC31237.1 - 0.013 15.1 0.2 0.013 15.1 0.2 1.8 2 0 0 2 2 2 0 Putative metallopeptidase domain Methyltransf_18 PF12847.7 EGC31237.1 - 0.076 12.9 0.1 0.28 11.1 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CK2S PF15011.6 EGC31237.1 - 0.15 11.9 7.7 0.16 11.8 1.7 3.3 2 1 1 3 3 3 0 Casein Kinase 2 substrate DUF1548 PF07579.11 EGC31237.1 - 1.8 8.9 7.9 0.85 10.0 0.7 3.2 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1548) Nod1 PF17114.5 EGC31237.1 - 2.1 8.5 7.0 0.31 11.2 1.1 2.7 2 0 0 2 2 2 0 Gef2-related medial cortical node protein Nod1 TGT PF01702.18 EGC31238.1 - 4.1e-92 309.0 0.1 1.2e-65 222.0 0.0 2.0 1 1 1 2 2 2 2 Queuine tRNA-ribosyltransferase DDA1 PF10172.9 EGC31238.1 - 0.062 13.6 0.2 0.17 12.2 0.2 1.7 1 0 0 1 1 1 0 Det1 complexing ubiquitin ligase Bromodomain PF00439.25 EGC31240.1 - 2e-18 66.2 0.9 2e-18 66.2 0.9 3.2 3 0 0 3 3 3 1 Bromodomain DUF2975 PF11188.8 EGC31241.1 - 0.027 14.3 0.0 0.027 14.3 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) DUF805 PF05656.14 EGC31241.1 - 0.15 12.5 4.3 7.2 7.1 4.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF805) YibE_F PF07907.11 EGC31241.1 - 0.21 11.0 7.2 0.036 13.5 2.8 1.8 1 1 0 1 1 1 0 YibE/F-like protein WH2 PF02205.20 EGC31242.1 - 2.6e-05 23.9 0.0 4e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 WH2 motif NOG1_N PF17835.1 EGC31243.1 - 7.6e-53 178.8 1.2 7.6e-53 178.8 1.2 2.1 2 0 0 2 2 2 1 NOG1 N-terminal helical domain NOG1 PF06858.14 EGC31243.1 - 4.5e-25 87.2 0.4 1.2e-24 85.9 0.4 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.23 EGC31243.1 - 4.2e-19 68.7 0.0 1.4e-18 67.1 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.11 EGC31243.1 - 5.9e-19 67.8 5.1 7.5e-19 67.5 3.6 2.1 2 0 0 2 2 1 1 NOGCT (NUC087) domain FeoB_N PF02421.18 EGC31243.1 - 5.7e-12 45.4 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B DNA_pol_alpha_N PF12254.8 EGC31243.1 - 0.0029 17.6 2.4 0.027 14.5 0.8 2.8 2 0 0 2 2 2 1 DNA polymerase alpha subunit p180 N terminal AIG1 PF04548.16 EGC31243.1 - 0.0045 16.3 0.1 0.021 14.1 0.0 2.2 3 0 0 3 3 3 1 AIG1 family AAA_16 PF13191.6 EGC31243.1 - 0.011 16.1 2.0 0.022 15.1 0.0 2.6 2 2 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.10 EGC31243.1 - 0.012 15.0 1.1 0.062 12.7 0.0 2.7 3 0 0 3 3 3 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGC31243.1 - 0.029 14.3 0.0 0.35 10.7 0.0 2.6 2 1 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EGC31243.1 - 0.042 14.4 1.0 0.81 10.2 0.0 3.3 3 0 0 3 3 3 0 AAA domain Dynamin_N PF00350.23 EGC31243.1 - 0.097 12.7 3.9 5.6 7.0 0.0 3.4 2 1 1 3 3 3 0 Dynamin family MeaB PF03308.16 EGC31243.1 - 0.11 11.5 0.6 0.86 8.5 0.0 2.6 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Lip_prot_lig_C PF10437.9 EGC31243.1 - 1.9 8.6 4.4 4.1 7.5 0.0 3.2 4 0 0 4 4 4 0 Bacterial lipoate protein ligase C-terminus JIP_LZII PF16471.5 EGC31243.1 - 2.6 8.3 8.1 0.46 10.7 2.4 2.8 2 1 1 3 3 3 0 JNK-interacting protein leucine zipper II Pkinase_Tyr PF07714.17 EGC31244.1 - 1.5e-54 185.0 0.0 2.2e-54 184.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC31244.1 - 2.6e-45 154.8 0.0 4.1e-45 154.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Tmemb_40 PF10160.9 EGC31244.1 - 0.00011 21.7 7.2 0.00025 20.6 7.2 1.5 1 0 0 1 1 1 1 Predicted membrane protein FKBP_C PF00254.28 EGC31245.1 - 8.5e-25 86.9 0.0 9.6e-25 86.7 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase ACDC PF14733.6 EGC31246.1 - 0.013 15.8 2.4 0.013 15.8 2.4 3.5 3 0 0 3 3 3 0 AP2-coincident C-terminal LRR_6 PF13516.6 EGC31246.1 - 0.058 13.5 12.6 7.9 6.8 0.1 6.1 7 0 0 7 7 7 0 Leucine Rich repeat Ion_trans PF00520.31 EGC31247.1 - 0.011 15.0 0.1 0.011 15.0 0.1 1.2 1 0 0 1 1 1 0 Ion transport protein Amidohydro_1 PF01979.20 EGC31250.1 - 3.3e-66 223.9 0.6 4.1e-66 223.6 0.6 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGC31250.1 - 7e-13 48.8 0.1 1.7e-10 41.0 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase family A_deaminase PF00962.22 EGC31250.1 - 0.00033 20.1 0.0 0.00071 19.0 0.0 1.5 1 0 0 1 1 1 1 Adenosine/AMP deaminase Alpha-amyl_C PF09071.10 EGC31250.1 - 0.01 15.7 0.1 0.026 14.4 0.1 1.7 1 0 0 1 1 1 1 Alpha-amylase, C terminal MvaI_BcnI PF15515.6 EGC31250.1 - 0.024 14.5 0.3 0.052 13.4 0.3 1.5 1 0 0 1 1 1 0 MvaI/BcnI restriction endonuclease family DUF3430 PF11912.8 EGC31251.1 - 3.6e-32 112.1 36.0 3.6e-32 112.1 36.0 3.6 1 1 1 3 3 3 1 Protein of unknown function (DUF3430) RhoGEF PF00621.20 EGC31252.1 - 1.9e-45 155.4 4.0 1.9e-45 155.4 4.0 2.4 2 1 0 2 2 2 1 RhoGEF domain Arm PF00514.23 EGC31252.1 - 2.7e-17 62.1 8.0 0.00025 21.0 0.1 8.5 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat DUF4704 PF15787.5 EGC31252.1 - 0.0004 19.7 1.2 0.0004 19.7 1.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4704) PH PF00169.29 EGC31252.1 - 0.019 15.5 0.1 0.06 13.9 0.1 2.0 1 0 0 1 1 1 0 PH domain HEAT_EZ PF13513.6 EGC31252.1 - 3 8.4 4.6 77 3.9 0.2 4.6 5 1 1 6 6 6 0 HEAT-like repeat ORC6 PF05460.13 EGC31253.1 - 0.32 10.2 3.4 0.6 9.3 3.4 1.4 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Knl1_RWD_C PF18210.1 EGC31254.1 - 0.76 10.3 3.6 0.41 11.1 0.5 1.9 1 1 0 2 2 2 0 Knl1 RWD C-terminal domain AKAP7_NLS PF10469.9 EGC31255.1 - 8.7e-28 97.6 3.4 1.4e-27 97.0 3.4 1.3 1 1 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGC31255.1 - 3.7e-06 26.9 0.0 4.9e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily Corona_NS2A PF05213.12 EGC31255.1 - 2.4e-05 23.8 0.7 0.0021 17.4 0.0 2.0 2 0 0 2 2 2 2 Coronavirus NS2A protein LigT_PEase PF02834.16 EGC31255.1 - 3.3e-05 24.0 0.1 0.25 11.5 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase RNA_pol_Rpb1_5 PF04998.17 EGC31255.1 - 0.35 10.3 5.0 3 7.2 5.0 2.0 1 1 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PEN-2 PF10251.9 EGC31256.1 - 7.7e-26 90.3 10.3 8.7e-26 90.2 10.3 1.0 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase Metallophos PF00149.28 EGC31257.1 - 1.3e-17 65.0 2.7 2.6e-17 64.0 2.7 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGC31257.1 - 3.3e-17 62.8 2.5 3.3e-17 62.8 2.5 2.2 2 1 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGC31257.1 - 6.6e-17 62.1 3.0 1.4e-16 61.1 0.3 2.8 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGC31257.1 - 0.0031 17.7 0.0 0.0058 16.8 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF866 PF05907.13 EGC31257.1 - 0.11 12.4 0.8 0.22 11.4 0.0 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF866) ANAPC4_WD40 PF12894.7 EGC31258.1 - 2e-07 31.2 0.2 0.03 14.6 0.1 3.7 1 1 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGC31258.1 - 0.00034 20.6 2.4 0.018 15.1 0.1 3.8 4 1 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.32 EGC31258.1 - 0.012 16.5 2.1 23 6.1 0.0 4.5 5 0 0 5 5 5 0 WD domain, G-beta repeat UDG PF03167.19 EGC31259.1 - 0.056 13.4 0.2 0.18 11.8 0.1 1.7 1 1 1 2 2 2 0 Uracil DNA glycosylase superfamily Peptidase_S30 PF01577.16 EGC31259.1 - 0.087 12.4 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease BBS2_N PF14781.6 EGC31259.1 - 0.4 10.6 6.6 7.9 6.4 3.3 3.0 1 1 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal GBS_Bsp-like PF08481.10 EGC31262.1 - 0.013 15.6 0.1 0.016 15.3 0.1 1.1 1 0 0 1 1 1 0 GBS Bsp-like repeat SUKH-3 PF14433.6 EGC31264.1 - 0.098 13.1 0.0 0.17 12.3 0.0 1.3 1 0 0 1 1 1 0 SUKH-3 immunity protein Methyltransf_16 PF10294.9 EGC31266.1 - 1.9e-27 96.1 4.1 4.5e-16 59.1 0.1 2.1 1 1 1 2 2 2 2 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC31266.1 - 2.5e-08 33.9 0.0 3.7e-08 33.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain GidB PF02527.15 EGC31266.1 - 0.0014 18.0 0.0 0.063 12.6 0.0 2.3 2 0 0 2 2 2 1 rRNA small subunit methyltransferase G PrmA PF06325.13 EGC31266.1 - 0.0026 17.2 0.6 0.0097 15.3 0.2 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGC31266.1 - 0.0048 16.5 0.1 0.36 10.4 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_12 PF08242.12 EGC31266.1 - 0.016 15.9 0.5 0.16 12.7 0.5 2.3 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGC31266.1 - 0.025 14.4 0.8 0.042 13.6 0.8 1.5 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGC31266.1 - 0.049 14.3 0.0 2.1 9.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain TFA2_Winged_2 PF18121.1 EGC31266.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 TFA2 Winged helix domain 2 TrmO PF01980.16 EGC31267.1 - 2.8e-40 137.2 0.0 5.1e-40 136.4 0.0 1.4 1 0 0 1 1 1 1 tRNA-methyltransferase O MIG-14_Wnt-bd PF06664.12 EGC31269.1 - 1.6e-61 208.1 33.3 1.2e-60 205.3 32.7 2.0 2 0 0 2 2 2 1 Wnt-binding factor required for Wnt secretion TMEM132D_C PF15706.5 EGC31269.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.5 2 0 0 2 2 2 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term Histone PF00125.24 EGC31270.1 - 1e-07 32.3 5.2 1e-07 32.3 5.2 4.8 5 1 1 6 6 6 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC31270.1 - 0.00069 19.8 0.0 0.0023 18.2 0.0 2.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TCL1_MTCP1 PF01840.17 EGC31272.1 - 0.77 9.4 2.6 21 4.8 0.1 3.3 4 0 0 4 4 4 0 TCL1/MTCP1 family RELT PF12606.8 EGC31273.1 - 0.07 12.1 1.0 0.13 11.3 1.0 1.4 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 IMS PF00817.20 EGC31275.1 - 2.1e-41 141.4 0.0 4.4e-41 140.4 0.0 1.6 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.8 EGC31275.1 - 8.4e-06 25.8 0.2 2.3e-05 24.5 0.2 1.8 1 0 0 1 1 1 1 IMS family HHH motif Caps_synth_GfcC PF06251.11 EGC31275.1 - 0.00031 20.4 0.1 0.0036 17.0 0.1 2.1 1 1 1 2 2 2 1 Capsule biosynthesis GfcC IMS_C PF11799.8 EGC31275.1 - 0.079 13.7 0.0 0.35 11.6 0.0 2.1 1 1 0 1 1 1 0 impB/mucB/samB family C-terminal domain GN3L_Grn1 PF08701.11 EGC31276.1 - 2.1e-22 79.0 18.5 2.1e-22 79.0 18.5 4.5 4 1 0 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.23 EGC31276.1 - 8e-15 54.9 15.2 3.3e-14 52.9 0.1 4.2 3 2 2 5 5 5 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC31276.1 - 3.7e-11 42.8 4.6 1.2e-07 31.4 0.1 2.8 3 0 0 3 3 3 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC31276.1 - 1.9e-06 27.9 4.7 0.028 14.3 0.1 3.5 2 1 1 3 3 3 2 RsgA GTPase AAA_16 PF13191.6 EGC31276.1 - 0.00023 21.6 1.9 0.077 13.4 0.0 3.4 3 0 0 3 3 3 1 AAA ATPase domain GTP_EFTU PF00009.27 EGC31276.1 - 0.001 18.7 0.0 0.001 18.7 0.0 3.6 4 2 1 5 5 5 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGC31276.1 - 0.25 11.9 0.0 0.25 11.9 0.0 3.5 3 2 1 4 4 4 0 AAA domain Roc PF08477.13 EGC31276.1 - 1.4 9.1 6.8 3.5 7.9 0.0 3.7 3 1 1 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase UPF0767 PF15990.5 EGC31276.1 - 9.4 6.5 0.0 9.4 6.5 0.0 4.5 4 1 1 5 5 5 0 UPF0767 family RRM_1 PF00076.22 EGC31278.1 - 2.1e-12 46.7 0.2 3.3e-12 46.0 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGC31278.1 - 1.1e-05 25.3 2.0 1.1e-05 25.3 2.0 2.2 2 0 0 2 2 2 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGC31278.1 - 0.012 15.4 0.6 0.019 14.8 0.6 1.3 1 0 0 1 1 1 0 Zinc knuckle PP2C PF00481.21 EGC31279.1 - 4.6e-64 216.5 0.1 4.6e-64 216.5 0.1 2.0 2 0 0 2 2 2 1 Protein phosphatase 2C Ndc1_Nup PF09531.10 EGC31279.1 - 0.48 9.1 7.1 0.56 8.8 7.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EGC31279.1 - 0.7 9.1 6.9 0.94 8.6 6.9 1.4 1 0 0 1 1 1 0 ZIP Zinc transporter Macoilin PF09726.9 EGC31279.1 - 1.1 7.7 17.9 1.2 7.6 17.9 1.1 1 0 0 1 1 1 0 Macoilin family Presenilin PF01080.17 EGC31279.1 - 4.6 5.9 15.9 6.7 5.4 15.9 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGC31279.1 - 7.8 6.5 9.0 13 5.7 9.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region TP53IP5 PF15331.6 EGC31279.1 - 8.6 6.4 13.4 15 5.6 13.4 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sel1 PF08238.12 EGC31280.1 - 3.8e-05 24.2 0.5 5.1 7.9 0.0 4.3 4 0 0 4 4 4 2 Sel1 repeat TPR_19 PF14559.6 EGC31280.1 - 0.0014 19.1 0.2 0.004 17.6 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31280.1 - 0.0095 16.3 0.1 0.031 14.6 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31280.1 - 0.011 16.0 0.0 0.088 13.1 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31280.1 - 0.027 14.6 0.1 1.1 9.5 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Exonuc_VII_S PF02609.16 EGC31280.1 - 0.042 13.9 0.0 0.59 10.2 0.1 2.6 2 0 0 2 2 2 0 Exonuclease VII small subunit TPR_1 PF00515.28 EGC31280.1 - 0.061 13.2 0.7 8 6.5 0.1 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31280.1 - 0.096 13.4 0.7 1.4 9.7 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat G8 PF10162.9 EGC31281.1 - 2.9e-25 88.7 0.1 7.3e-25 87.4 0.1 1.7 1 0 0 1 1 1 1 G8 domain DUF11 PF01345.18 EGC31281.1 - 1.9 8.9 7.1 0.56 10.5 0.4 3.4 3 1 0 3 3 3 0 Domain of unknown function DUF11 TPR_17 PF13431.6 EGC31282.1 - 0.00015 21.9 11.0 0.00093 19.4 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat Csa1 PF06023.12 EGC31282.1 - 0.23 10.8 0.9 13 5.1 0.0 2.1 1 1 1 2 2 2 0 CRISPR-associated exonuclease Csa1 Symplekin_C PF12295.8 EGC31283.1 - 5.1e-53 179.9 3.0 5.1e-53 179.9 3.0 2.5 2 0 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.8 EGC31283.1 - 6.9e-46 156.7 10.2 6.9e-46 156.7 10.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3453) TAFH PF07531.14 EGC31283.1 - 0.012 15.7 1.0 7.7 6.7 0.1 3.7 2 0 0 2 2 2 0 NHR1 homology to TAF PCI PF01399.27 EGC31284.1 - 1.5e-17 64.0 0.3 1.5e-17 64.0 0.3 2.3 2 1 0 2 2 2 1 PCI domain CHAD PF05235.14 EGC31284.1 - 0.19 11.7 0.1 0.27 11.2 0.1 1.3 1 0 0 1 1 1 0 CHAD domain Mucin PF01456.17 EGC31285.1 - 6.4e-06 26.2 16.7 8.3e-06 25.8 16.7 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein GPR15L PF15854.5 EGC31285.1 - 0.04 14.1 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 MSA-2c PF12238.8 EGC31285.1 - 1.5 8.8 12.5 1.9 8.4 12.5 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c SOG2 PF10428.9 EGC31285.1 - 7.7 5.6 16.3 8.5 5.5 16.3 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein EMP24_GP25L PF01105.24 EGC31286.1 - 0.05 13.6 4.3 0.054 13.4 4.3 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4822 PF16103.5 EGC31286.1 - 0.055 13.8 5.1 0.53 10.6 2.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4822) Sif PF06767.11 EGC31286.1 - 0.089 11.8 2.1 1.1 8.1 0.3 2.1 1 1 0 2 2 2 0 Sif protein IRK_N PF08466.10 EGC31286.1 - 2.5 8.3 13.2 11 6.2 2.0 3.5 1 1 1 2 2 2 0 Inward rectifier potassium channel N-terminal Glyco_hydro_9 PF00759.19 EGC31287.1 - 5.6e-125 418.0 10.7 6.4e-125 417.8 10.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Glyco_hydro_127 PF07944.12 EGC31287.1 - 0.052 12.0 0.0 0.13 10.7 0.0 1.7 1 1 0 1 1 1 0 Beta-L-arabinofuranosidase, GH127 TOM20_plant PF06552.12 EGC31289.1 - 0.19 11.4 4.2 0.2 11.4 2.9 1.7 1 1 0 1 1 1 0 Plant specific mitochondrial import receptor subunit TOM20 CHASE3 PF05227.13 EGC31289.1 - 0.45 10.4 9.1 0.68 9.8 4.1 2.2 1 1 1 2 2 2 0 CHASE3 domain ALMT PF11744.8 EGC31289.1 - 0.79 8.5 19.9 1.3 7.8 19.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Fib_alpha PF08702.10 EGC31289.1 - 4.2 7.5 25.0 0.11 12.7 7.3 2.5 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Tweety PF04906.13 EGC31289.1 - 7.4 5.1 6.1 12 4.5 6.1 1.3 1 0 0 1 1 1 0 Tweety Med25_VWA PF11265.8 EGC31290.1 - 2.5e-07 30.8 0.0 5.6e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A G10 PF01125.17 EGC31291.1 - 0.0022 17.8 12.9 0.0022 17.8 12.9 4.2 4 1 0 4 4 4 2 G10 protein BAR_3 PF16746.5 EGC31292.1 - 6.9e-07 29.2 12.4 6.9e-07 29.2 12.4 2.1 2 1 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 EGC31292.1 - 0.0032 17.2 14.2 0.0075 15.9 14.2 1.7 1 1 0 1 1 1 1 BAR domain Sec5 PF15469.6 EGC31294.1 - 1.7e-45 155.2 8.8 1.7e-45 155.2 8.8 3.8 3 1 0 3 3 3 1 Exocyst complex component Sec5 RA PF00788.23 EGC31294.1 - 1.5e-05 25.5 1.2 8e-05 23.2 1.2 2.4 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Glyco_hydro_64 PF16483.5 EGC31294.1 - 0.0054 16.1 0.2 0.011 15.1 0.2 1.4 1 0 0 1 1 1 1 Beta-1,3-glucanase DUF5566 PF17721.1 EGC31294.1 - 0.067 13.4 3.9 0.16 12.2 3.9 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5566) Vps23_core PF09454.10 EGC31294.1 - 0.078 12.9 0.4 6.8 6.7 0.1 2.9 2 0 0 2 2 2 0 Vps23 core domain Ank_2 PF12796.7 EGC31295.1 - 1.4e-11 44.8 14.8 1.2e-06 29.0 0.6 3.5 1 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC31295.1 - 2e-07 31.4 0.9 0.0037 17.8 0.1 3.2 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC31295.1 - 0.0013 19.0 0.5 18 6.3 0.0 4.8 3 1 1 4 4 4 1 Ankyrin repeat Ank_5 PF13857.6 EGC31295.1 - 0.029 14.7 0.2 0.029 14.7 0.2 5.5 3 2 3 6 6 6 0 Ankyrin repeats (many copies) zf-RING_2 PF13639.6 EGC31296.1 - 7.7e-10 38.9 12.8 1.6e-09 38.0 10.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC31296.1 - 6.8e-09 35.4 8.6 1.5e-08 34.3 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC31296.1 - 7.1e-09 35.4 7.5 2e-08 33.9 7.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31296.1 - 4.1e-07 29.7 10.5 4.1e-07 29.7 10.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC31296.1 - 1e-06 28.7 4.2 2.4e-06 27.4 4.2 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC31296.1 - 0.00012 22.3 7.7 0.00037 20.7 7.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGC31296.1 - 0.00043 20.0 5.1 0.0012 18.5 5.1 1.9 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_5 PF14634.6 EGC31296.1 - 0.00073 19.4 8.1 0.00073 19.4 8.1 2.3 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC31296.1 - 0.0014 18.7 9.0 0.0014 18.7 9.0 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC31296.1 - 0.0065 16.2 10.7 0.017 14.9 10.7 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC31296.1 - 0.058 13.5 2.1 0.13 12.3 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGC31296.1 - 0.066 13.1 6.6 0.19 11.6 6.6 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zinc_ribbon_9 PF14369.6 EGC31296.1 - 0.16 12.3 6.6 0.44 10.9 6.6 1.8 1 0 0 1 1 1 0 zinc-ribbon Zn_ribbon_17 PF17120.5 EGC31296.1 - 0.19 11.4 7.2 0.39 10.4 7.2 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EGC31296.1 - 0.22 11.4 1.9 0.49 10.3 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TM2 PF05154.16 EGC31297.1 - 1.7e-19 69.8 8.3 2.5e-19 69.3 8.3 1.2 1 0 0 1 1 1 1 TM2 domain EGF_2 PF07974.13 EGC31298.1 - 2.3e-08 34.3 59.3 5.1e-05 23.6 13.9 3.9 3 0 0 3 3 3 3 EGF-like domain Tme5_EGF_like PF09064.10 EGC31298.1 - 0.00084 19.2 4.0 0.00084 19.2 4.0 4.0 2 1 1 3 3 3 1 Thrombomodulin like fifth domain, EGF-like CAF1 PF04857.20 EGC31299.1 - 2.8e-61 207.4 13.3 3.8e-60 203.7 13.3 2.0 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.20 EGC31299.1 - 0.00033 20.4 1.6 0.082 12.6 0.6 2.3 2 0 0 2 2 2 2 3'-5' exonuclease HTH_16 PF12645.7 EGC31300.1 - 0.047 13.7 0.0 0.19 11.8 0.0 2.1 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_12 PF08242.12 EGC31301.1 - 1.5e-14 54.5 0.1 4.5e-14 53.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC31301.1 - 1.9e-12 47.4 0.0 2.4e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC31301.1 - 6.3e-11 42.8 0.0 1.1e-10 42.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC31301.1 - 2.8e-08 33.7 0.0 4.5e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC31301.1 - 9.5e-08 32.6 0.0 2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC31301.1 - 5.2e-05 22.7 0.1 6.8e-05 22.3 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC31301.1 - 0.0014 18.2 0.0 0.0027 17.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.12 EGC31301.1 - 0.0021 17.6 0.0 0.003 17.1 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase CheR PF01739.18 EGC31301.1 - 0.0033 16.9 0.0 1.9 8.0 0.0 2.4 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain TPMT PF05724.11 EGC31301.1 - 0.072 12.7 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_24 PF13578.6 EGC31301.1 - 0.14 13.2 0.0 0.43 11.6 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain GCN5L1 PF06320.13 EGC31302.1 - 1.6e-43 147.4 4.3 1.6e-43 147.4 4.3 1.3 2 0 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) DUF3972 PF13118.6 EGC31302.1 - 0.014 15.9 0.9 0.026 15.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) SoPB_HTH PF18090.1 EGC31302.1 - 0.073 13.2 0.0 8.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Centromere-binding protein HTH domain DegS PF05384.11 EGC31302.1 - 0.1 12.1 4.2 2.5 7.6 0.1 2.7 1 1 2 3 3 3 0 Sensor protein DegS DUF5595 PF18077.1 EGC31302.1 - 0.12 12.5 1.1 0.74 9.9 0.6 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DivIC PF04977.15 EGC31302.1 - 0.14 12.0 0.3 0.14 12.0 0.3 2.7 3 0 0 3 3 3 0 Septum formation initiator Leu_zip PF15294.6 EGC31302.1 - 0.17 11.4 6.0 0.39 10.2 6.0 1.6 1 1 0 1 1 1 0 Leucine zipper HMMR_C PF15908.5 EGC31302.1 - 0.68 10.2 7.2 1.5 9.0 0.5 2.6 2 1 1 3 3 3 0 Hyaluronan mediated motility receptor C-terminal UPF0242 PF06785.11 EGC31302.1 - 7.9 6.5 11.7 6.1 6.9 3.4 2.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Myb_DNA-binding PF00249.31 EGC31303.1 - 1.9e-12 47.2 0.3 2.7e-11 43.5 0.1 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.17 EGC31303.1 - 4.8e-09 35.9 3.8 1.2e-08 34.7 3.8 1.6 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.17 EGC31303.1 - 1.8e-08 34.6 0.7 2.5e-07 30.9 0.1 2.8 2 0 0 2 2 2 1 SWIRM domain C1_2 PF03107.16 EGC31303.1 - 0.019 15.3 4.0 0.042 14.2 4.0 1.6 1 0 0 1 1 1 0 C1 domain Glyco_hydro_18 PF00704.28 EGC31304.1 - 3.6e-19 69.6 0.0 4.9e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EamA PF00892.20 EGC31305.1 - 1.5e-17 64.0 33.0 6.6e-08 32.8 12.6 3.1 3 0 0 3 3 3 3 EamA-like transporter family SLC35F PF06027.12 EGC31305.1 - 6.4e-09 35.7 15.3 1.1e-08 35.0 15.3 1.3 1 0 0 1 1 1 1 Solute carrier family 35 TPT PF03151.16 EGC31305.1 - 6.7e-09 35.5 10.3 9.8e-09 35.0 10.3 1.3 1 0 0 1 1 1 1 Triose-phosphate Transporter family PUNUT PF16913.5 EGC31305.1 - 1.6e-08 34.2 4.6 1.6e-08 34.2 4.6 2.5 3 0 0 3 3 3 1 Purine nucleobase transmembrane transport CRT-like PF08627.10 EGC31305.1 - 1.1e-05 24.6 15.0 0.012 14.6 6.1 2.3 1 1 1 2 2 2 2 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 EGC31305.1 - 2.1e-05 24.3 9.6 0.00017 21.3 7.8 2.5 1 1 1 2 2 2 1 Putative multidrug resistance efflux transporter EF-hand_1 PF00036.32 EGC31306.1 - 1.3e-12 46.3 11.9 7.1e-05 22.1 0.2 5.0 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.6 EGC31306.1 - 3.6e-10 40.1 6.0 0.0017 18.8 2.9 3.2 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC31306.1 - 6.2e-10 38.2 12.8 0.0021 17.8 0.2 4.7 4 1 1 5 5 5 3 EF-hand domain EF-hand_8 PF13833.6 EGC31306.1 - 8.8e-09 35.1 15.5 0.00015 21.5 0.7 4.4 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.7 EGC31306.1 - 1.3e-05 25.1 6.2 0.069 13.1 0.2 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.6 EGC31306.1 - 0.00047 20.4 0.1 1.3 9.4 0.1 2.5 2 1 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGC31306.1 - 0.012 15.1 11.3 3.3 7.4 0.0 4.6 5 0 0 5 5 5 0 EF hand Myb_DNA-binding PF00249.31 EGC31307.1 - 1.6e-37 127.5 11.9 1e-14 54.4 1.0 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC31307.1 - 5.3e-31 106.7 7.4 6.4e-16 58.4 0.3 4.1 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGC31307.1 - 5.3e-08 32.9 0.2 0.031 14.3 0.0 3.9 2 1 1 3 3 3 2 SLIDE SANT_DAMP1_like PF16282.5 EGC31307.1 - 0.028 14.6 4.7 2.4 8.4 0.2 3.4 1 1 2 3 3 3 0 SANT/Myb-like domain of DAMP1 Myb_DNA-bind_7 PF15963.5 EGC31307.1 - 0.046 13.6 4.6 12 5.8 0.0 3.9 3 1 0 3 3 3 0 Myb DNA-binding like MADF_DNA_bdg PF10545.9 EGC31307.1 - 1.4 9.3 6.2 3.7 7.9 0.1 3.2 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like WD40 PF00400.32 EGC31308.1 - 5.9e-22 77.6 18.7 0.00016 22.4 0.2 7.6 7 1 1 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC31308.1 - 4.2e-17 62.2 1.3 3.2e-07 30.6 0.0 4.9 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC31308.1 - 0.0011 18.1 1.8 0.21 10.5 0.1 2.8 1 1 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Hira PF07569.11 EGC31308.1 - 0.036 13.8 0.1 0.036 13.8 0.1 4.0 3 2 0 3 3 3 0 TUP1-like enhancer of split PspA_IM30 PF04012.12 EGC31308.1 - 0.043 13.4 1.3 0.067 12.8 1.3 1.2 1 0 0 1 1 1 0 PspA/IM30 family DUF1765 PF08578.10 EGC31309.1 - 6.2e-24 84.9 5.2 6.2e-24 84.9 5.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Vault PF01505.18 EGC31310.1 - 6.8e-61 202.2 0.1 1.3e-14 54.0 0.0 5.4 6 0 0 6 6 6 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 EGC31310.1 - 1.3e-53 180.0 0.8 2.7e-53 179.0 0.8 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 EGC31310.1 - 5.6e-39 132.3 0.2 2.1e-26 92.0 0.1 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 EGC31310.1 - 3.5e-35 119.9 0.2 4.5e-31 106.7 0.0 2.7 2 0 0 2 2 2 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 EGC31310.1 - 3.1e-25 88.0 0.0 3.9e-23 81.3 0.1 3.5 3 0 0 3 3 3 1 Major Vault Protein repeat domain DUF2543 PF10820.8 EGC31310.1 - 0.36 11.0 2.0 8.5 6.6 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2543) tRNA-synt_His PF13393.6 EGC31311.1 - 1.8e-37 129.3 0.0 3.1e-37 128.5 0.0 1.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.25 EGC31311.1 - 1.6e-12 47.8 0.1 3.5e-12 46.7 0.1 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGC31311.1 - 7e-09 35.7 0.0 2.8e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.20 EGC31311.1 - 0.043 12.9 0.4 0.47 9.5 0.1 2.5 2 1 0 2 2 2 0 tRNA synthetases class II (D, K and N) G3P_antiterm PF04309.12 EGC31311.1 - 0.079 12.4 0.0 0.14 11.5 0.0 1.3 1 0 0 1 1 1 0 Glycerol-3-phosphate responsive antiterminator RRP7 PF12923.7 EGC31312.1 - 4.3e-26 91.4 9.0 4.3e-26 91.4 9.0 3.8 3 1 1 4 4 4 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain Trypan_PARP PF05887.11 EGC31312.1 - 0.0062 16.5 17.3 0.0062 16.5 17.3 1.9 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Kin17_mid PF10357.9 EGC31313.1 - 2.5e-45 153.5 5.7 2.5e-45 153.5 5.7 2.4 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein KN17_SH3 PF18131.1 EGC31313.1 - 5.9e-20 71.1 6.3 6.7e-19 67.8 4.0 2.5 2 0 0 2 2 2 1 KN17 SH3-like C-terminal domain zf-met PF12874.7 EGC31313.1 - 0.00031 21.0 3.8 0.00072 19.9 3.8 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC31313.1 - 0.00085 19.6 4.1 0.00085 19.6 4.1 2.4 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGC31313.1 - 0.024 15.0 0.5 0.024 15.0 0.5 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) KOW PF00467.29 EGC31313.1 - 0.13 12.3 0.2 0.31 11.1 0.2 1.7 1 0 0 1 1 1 0 KOW motif SpoU_methylase PF00588.19 EGC31314.1 - 7.6e-28 97.5 0.4 5.3e-25 88.2 0.4 2.2 1 1 0 1 1 1 1 SpoU rRNA Methylase family BaxI_1 PF12811.7 EGC31314.1 - 0.025 14.2 0.1 0.036 13.6 0.1 1.2 1 0 0 1 1 1 0 Bax inhibitor 1 like Sep15_SelM PF08806.11 EGC31315.1 - 1.2e-09 38.2 0.0 1.7e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 Sep15/SelM redox domain DUF905 PF06006.12 EGC31315.1 - 0.18 11.8 0.0 0.23 11.5 0.0 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF905) DUF4365 PF14280.6 EGC31316.1 - 0.41 10.6 4.5 0.22 11.4 0.8 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4365) DUF3430 PF11912.8 EGC31317.1 - 1.1e-27 97.5 32.5 1.2e-27 97.4 32.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) PLA2_B PF01735.18 EGC31318.1 - 0.25 9.7 3.8 0.29 9.5 3.8 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain DUF4551 PF15087.6 EGC31319.1 - 1.5 7.5 4.9 1.8 7.3 4.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CH PF00307.31 EGC31320.1 - 1.7e-15 57.1 0.8 1.7e-15 57.1 0.8 2.0 3 0 0 3 3 3 1 Calponin homology (CH) domain SR-25 PF10500.9 EGC31321.1 - 8.7e-14 51.7 0.2 9.8e-14 51.5 0.2 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Auto_anti-p27 PF06677.12 EGC31322.1 - 5.1e-31 106.5 6.4 9e-16 57.8 0.3 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) DUF4315 PF14193.6 EGC31322.1 - 0.012 15.7 0.7 0.04 13.9 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4315) MMR1 PF08505.10 EGC31322.1 - 1.2 9.4 24.3 1.9 8.8 12.5 2.2 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Ribosomal_S27e PF01667.17 EGC31322.1 - 2.7 7.8 4.7 0.42 10.4 0.7 1.7 2 0 0 2 2 2 0 Ribosomal protein S27 DUF4175 PF13779.6 EGC31323.1 - 0.73 7.7 15.3 1.3 6.9 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) FNIP PF05725.12 EGC31324.1 - 2.3e-11 43.7 17.2 1.1e-06 28.6 0.3 6.2 3 2 2 5 5 5 3 FNIP Repeat DUF1725 PF08333.11 EGC31324.1 - 0.23 11.2 1.7 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) 2OG-FeII_Oxy_5 PF13759.6 EGC31325.1 - 1.7 9.1 10.4 4.6 7.7 4.0 2.2 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase FNIP PF05725.12 EGC31326.1 - 2e-11 43.8 6.1 1.1e-06 28.6 0.3 6.0 3 3 3 6 6 6 3 FNIP Repeat FNIP PF05725.12 EGC31327.1 - 0.0072 16.5 1.1 0.24 11.6 1.1 2.3 1 1 0 1 1 1 1 FNIP Repeat DUF3430 PF11912.8 EGC31329.1 - 6.5e-21 75.4 29.1 6.5e-21 75.4 29.1 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) BTB PF00651.31 EGC31329.1 - 0.13 12.5 0.2 0.19 11.9 0.2 1.3 1 0 0 1 1 1 0 BTB/POZ domain PKI PF02827.16 EGC31330.1 - 2.3 8.5 10.4 0.14 12.4 1.5 2.8 2 1 1 3 3 3 0 cAMP-dependent protein kinase inhibitor LRR_4 PF12799.7 EGC31331.1 - 8.3e-34 115.1 79.9 4.3e-06 27.0 2.4 9.5 4 3 3 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC31331.1 - 1.4e-29 101.6 64.3 8.6e-08 31.8 5.3 8.1 4 3 3 7 7 7 7 Leucine rich repeat LRR_9 PF14580.6 EGC31331.1 - 7.8e-08 32.0 31.0 0.00072 19.1 2.4 5.1 1 1 4 5 5 5 5 Leucine-rich repeat LRR_1 PF00560.33 EGC31331.1 - 5.4e-07 29.3 59.6 0.58 10.9 0.1 15.2 15 1 0 15 15 15 3 Leucine Rich Repeat LRR_6 PF13516.6 EGC31331.1 - 0.0083 16.1 57.2 0.62 10.3 1.0 12.7 15 0 0 15 15 15 5 Leucine Rich repeat Pentapeptide_4 PF13599.6 EGC31331.1 - 0.12 12.5 0.6 20 5.4 0.0 3.8 3 1 1 4 4 4 0 Pentapeptide repeats (9 copies) LRR_5 PF13306.6 EGC31331.1 - 1.7 8.6 25.7 0.1 12.5 11.8 3.5 1 1 0 2 2 2 0 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC31332.1 - 1.1e-19 70.2 7.1 7.4e-10 38.8 0.1 2.8 2 1 1 3 3 3 3 FNIP Repeat DUF2951 PF11166.8 EGC31333.1 - 0.79 10.0 4.5 0.96 9.7 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) MMgT PF10270.9 EGC31335.1 - 4 7.9 5.6 0.81 10.1 0.2 2.8 3 0 0 3 3 3 0 Membrane magnesium transporter DUF4972 PF16342.5 EGC31336.1 - 0.0023 17.6 1.8 0.0058 16.3 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) Sid-5 PF17204.3 EGC31336.1 - 0.56 10.4 0.0 0.56 10.4 0.0 4.0 2 1 2 4 4 4 0 Sid-5 family CENP-R PF06729.12 EGC31340.1 - 0.13 12.2 7.2 0.1 12.5 3.0 2.0 1 1 1 2 2 2 0 Kinetochore component, CENP-R Macoilin PF09726.9 EGC31341.1 - 9.4 4.7 12.1 11 4.4 12.1 1.1 1 0 0 1 1 1 0 Macoilin family zf-RING_2 PF13639.6 EGC31342.1 - 1.8e-15 57.0 7.9 2e-15 56.8 7.9 1.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC31342.1 - 5.8e-10 38.7 6.3 1.1e-09 37.9 6.3 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGC31342.1 - 1.2e-09 37.9 7.3 1.5e-09 37.5 7.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31342.1 - 1.6e-09 37.9 8.9 6.9e-09 35.9 8.9 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC31342.1 - 1.5e-07 31.3 2.2 1.5e-07 31.3 2.2 1.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC31342.1 - 2.8e-07 30.4 6.1 3.3e-07 30.2 6.1 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGC31342.1 - 4.8e-07 29.5 7.3 5.9e-07 29.2 7.3 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC31342.1 - 7.7e-06 25.7 4.5 9.5e-06 25.4 4.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGC31342.1 - 0.00011 22.2 4.5 0.00017 21.6 4.5 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGC31342.1 - 0.00014 21.6 6.4 0.00036 20.3 6.4 1.6 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGC31342.1 - 0.0004 20.5 8.2 0.003 17.7 8.2 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain RINGv PF12906.7 EGC31342.1 - 0.00074 19.6 6.6 0.0011 19.1 6.6 1.2 1 0 0 1 1 1 1 RING-variant domain Zn_ribbon_17 PF17120.5 EGC31342.1 - 0.0011 18.6 7.2 0.002 17.7 7.2 1.5 1 1 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-Nse PF11789.8 EGC31342.1 - 0.0025 17.6 3.4 0.003 17.4 3.4 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_1 PF14446.6 EGC31342.1 - 0.0026 17.7 7.3 0.0086 16.0 2.9 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-C3H2C3 PF17122.5 EGC31342.1 - 0.0066 16.5 5.3 0.0066 16.5 5.3 2.0 2 1 0 2 2 1 1 Zinc-finger zf-P11 PF03854.14 EGC31342.1 - 0.01 15.5 1.8 0.01 15.5 1.8 1.9 1 1 1 2 2 2 0 P-11 zinc finger zf-RING_9 PF13901.6 EGC31342.1 - 0.032 14.2 5.2 0.038 14.0 5.2 1.1 1 0 0 1 1 1 0 Putative zinc-RING and/or ribbon Baculo_IE-1 PF05290.11 EGC31342.1 - 0.034 14.1 2.3 0.041 13.8 2.3 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-RING_4 PF14570.6 EGC31342.1 - 0.052 13.3 4.1 0.15 11.9 4.1 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING-like PF08746.11 EGC31342.1 - 0.17 12.2 7.1 0.74 10.2 7.1 2.0 1 1 0 1 1 1 0 RING-like domain Vps39_2 PF10367.9 EGC31342.1 - 0.21 12.0 4.1 1.9 9.0 1.2 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-C3HC4_4 PF15227.6 EGC31342.1 - 0.28 11.4 6.8 2.5 8.3 6.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING OrfB_Zn_ribbon PF07282.11 EGC31342.1 - 0.35 10.8 3.8 0.47 10.4 0.4 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain PHD PF00628.29 EGC31342.1 - 0.56 10.1 7.9 1.4 8.9 7.9 1.7 1 1 0 1 1 1 0 PHD-finger DHHC PF01529.20 EGC31343.1 - 4.5e-37 127.1 10.7 4.5e-37 127.1 10.7 2.1 2 0 0 2 2 2 1 DHHC palmitoyltransferase SNAP PF14938.6 EGC31344.1 - 3.1e-109 364.8 14.7 3.5e-109 364.6 14.7 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGC31344.1 - 4.1e-08 33.4 10.6 0.0015 18.7 0.1 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31344.1 - 7.6e-08 32.9 8.3 0.0035 18.0 0.6 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31344.1 - 7e-06 26.5 9.8 0.017 15.6 0.1 4.7 3 2 1 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 EGC31344.1 - 3.7e-05 23.5 3.4 0.00012 21.8 1.6 2.2 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_1 PF00515.28 EGC31344.1 - 4.9e-05 23.0 18.0 0.51 10.3 0.9 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31344.1 - 6.7e-05 23.3 18.0 0.48 11.2 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC31344.1 - 0.00024 20.6 1.8 0.00035 20.1 1.8 1.1 1 0 0 1 1 1 1 MalT-like TPR region TPR_7 PF13176.6 EGC31344.1 - 0.00034 20.4 12.0 0.23 11.6 0.2 5.3 4 2 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31344.1 - 0.00035 20.5 25.9 0.24 11.6 0.1 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat Spatacsin_C PF14649.6 EGC31344.1 - 0.00066 18.9 7.1 0.0035 16.5 0.9 2.9 1 1 2 3 3 3 1 Spatacsin C-terminus TPR_14 PF13428.6 EGC31344.1 - 0.00078 20.1 7.3 0.82 10.7 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31344.1 - 0.00094 19.4 9.8 0.18 12.1 0.2 4.1 3 1 1 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF2225 PF09986.9 EGC31344.1 - 0.01 15.6 3.9 0.019 14.7 3.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) DHR-2 PF06920.13 EGC31344.1 - 0.016 13.9 2.7 0.017 13.8 0.5 1.9 1 1 1 2 2 2 0 Dock homology region 2 SHNi-TPR PF10516.9 EGC31344.1 - 0.018 14.5 0.2 0.55 9.7 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_8 PF13181.6 EGC31344.1 - 0.16 12.3 0.3 0.16 12.3 0.3 5.7 6 2 1 7 7 6 0 Tetratricopeptide repeat Foie-gras_1 PF11817.8 EGC31344.1 - 0.18 11.4 2.9 6.6 6.2 2.3 2.2 1 1 0 1 1 1 0 Foie gras liver health family 1 MIT PF04212.18 EGC31344.1 - 0.47 10.5 17.6 1.2 9.3 2.2 5.0 2 1 3 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_11 PF13414.6 EGC31344.1 - 0.92 9.3 16.3 1.5 8.6 0.1 4.3 4 1 1 5 5 5 0 TPR repeat Actin PF00022.19 EGC31345.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin DnaJ PF00226.31 EGC31346.1 - 3e-10 40.1 0.2 5.2e-10 39.3 0.2 1.4 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.13 EGC31346.1 - 3.5e-10 40.0 0.1 3.8e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Pam16 RPT PF13446.6 EGC31346.1 - 0.014 15.3 0.2 0.24 11.3 0.0 2.2 2 0 0 2 2 2 0 A repeated domain in UCH-protein zf-H2C2_5 PF13909.6 EGC31347.1 - 4.7e-05 23.1 2.3 0.00011 21.8 2.3 1.6 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.7 EGC31347.1 - 0.022 15.1 0.9 0.022 15.1 0.9 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) OrsD PF12013.8 EGC31347.1 - 0.063 13.7 0.7 0.063 13.7 0.7 2.6 1 1 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D zf-C2H2 PF00096.26 EGC31347.1 - 0.094 13.2 0.8 0.094 13.2 0.8 3.1 3 0 0 3 3 3 0 Zinc finger, C2H2 type zf-C4pol PF14260.6 EGC31347.1 - 0.18 12.3 5.9 0.4 11.2 1.4 2.4 2 0 0 2 2 2 0 C4-type zinc-finger of DNA polymerase delta zf-C2H2_4 PF13894.6 EGC31347.1 - 1.3 10.1 5.6 0.46 11.5 0.7 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger CRAL_TRIO_2 PF13716.6 EGC31348.1 - 2.3e-21 76.4 1.4 6e-21 75.1 1.4 1.7 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Macro PF01661.21 EGC31348.1 - 4.5e-16 58.9 0.2 1e-15 57.8 0.0 1.7 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.20 EGC31348.1 - 9.4e-10 38.4 0.7 2.8e-09 36.9 0.1 2.1 3 0 0 3 3 3 1 CRAL/TRIO domain zf-C3H2C3 PF17122.5 EGC31348.1 - 0.17 12.0 1.9 0.98 9.5 0.6 2.2 2 0 0 2 2 2 0 Zinc-finger 4HBT PF03061.22 EGC31349.1 - 3.2e-08 33.8 0.0 4.9e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily JAB PF01398.21 EGC31350.1 - 7.5e-34 116.2 0.2 1.4e-33 115.3 0.2 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease CSN5_C PF18323.1 EGC31350.1 - 2.3e-23 82.9 3.9 4.1e-23 82.1 3.9 1.4 1 0 0 1 1 1 1 Cop9 signalosome subunit 5 C-terminal domain Prok-JAB PF14464.6 EGC31350.1 - 4.7e-05 23.1 0.0 7.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.13 EGC31350.1 - 0.0055 16.8 0.8 0.01 15.9 0.1 1.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) CK_II_beta PF01214.18 EGC31351.1 - 3.7e-78 261.5 0.0 3.7e-78 261.5 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit CxC5 PF18718.1 EGC31351.1 - 0.022 14.9 0.1 0.022 14.9 0.1 1.8 2 0 0 2 2 2 0 CxC5 like cysteine cluster associated with KDZ transposases MscS_TM PF12794.7 EGC31351.1 - 0.024 13.5 3.9 1.2 7.9 0.0 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 Adap_comp_sub PF00928.21 EGC31352.1 - 5.4e-26 91.5 0.8 8.8e-26 90.8 0.8 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family HlyD_D23 PF16576.5 EGC31352.1 - 0.076 12.2 1.2 0.13 11.5 1.2 1.3 1 0 0 1 1 1 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion Kinesin PF00225.23 EGC31353.1 - 8.3e-102 340.5 7.3 9.6e-102 340.3 7.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGC31353.1 - 1e-19 70.9 0.8 1.3e-18 67.3 0.1 2.5 2 0 0 2 2 2 1 Microtubule binding Urm1 PF09138.11 EGC31354.1 - 9.9e-37 125.2 0.3 1.1e-36 125.1 0.3 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.20 EGC31354.1 - 0.036 14.7 0.0 0.043 14.5 0.0 1.2 1 0 0 1 1 1 0 ThiS family Peptidase_C54 PF03416.19 EGC31355.1 - 5.2e-99 331.1 0.1 1.1e-98 330.0 0.1 1.5 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.13 EGC31355.1 - 0.0053 16.3 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Peptidase family C78 TRM13 PF05206.14 EGC31355.1 - 0.068 12.7 0.2 0.068 12.7 0.2 3.4 3 1 0 3 3 3 0 Methyltransferase TRM13 DUF4228 PF14009.6 EGC31355.1 - 0.12 12.7 0.2 0.12 12.7 0.2 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4228) DUF2701 PF10857.8 EGC31355.1 - 0.13 12.3 0.0 0.31 11.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2701) Ctr PF04145.15 EGC31355.1 - 2.4 8.8 6.8 0.95 10.1 0.1 2.9 3 0 0 3 3 3 0 Ctr copper transporter family Rhodanese PF00581.20 EGC31356.1 - 1.6e-08 35.0 0.7 8.5e-08 32.7 0.0 2.6 2 0 0 2 2 2 1 Rhodanese-like domain FNIP PF05725.12 EGC31360.1 - 3.8e-178 577.5 36.5 6.9e-15 54.9 0.0 14.3 7 2 7 16 16 16 16 FNIP Repeat Peptidase_C25_C PF03785.14 EGC31360.1 - 0.057 13.3 3.4 53 3.8 0.0 6.0 6 0 0 6 6 6 0 Peptidase family C25, C terminal ig-like domain Bromodomain PF00439.25 EGC31361.1 - 7.7e-09 35.5 0.4 2.1e-08 34.1 0.4 1.8 1 0 0 1 1 1 1 Bromodomain PHD PF00628.29 EGC31361.1 - 0.00035 20.4 4.5 0.00035 20.4 4.5 3.2 4 0 0 4 4 4 1 PHD-finger GAIN_A PF18619.1 EGC31361.1 - 0.0043 17.2 0.1 0.017 15.3 0.1 2.0 1 0 0 1 1 1 1 GPCR-Autoproteolysis-INducing (GAIN) subdomain A PHD_2 PF13831.6 EGC31361.1 - 0.0079 15.7 3.5 0.0079 15.7 3.5 2.6 3 0 0 3 3 3 1 PHD-finger Sld3_N PF18523.1 EGC31361.1 - 0.024 14.8 1.1 0.092 12.9 1.1 2.0 1 0 0 1 1 1 0 Sld3 N-terminal domain ECH_1 PF00378.20 EGC31362.1 - 2.2e-58 197.5 0.0 2.6e-58 197.3 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC31362.1 - 2.8e-41 142.1 0.1 4.3e-33 115.2 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase SpoU_methylase PF00588.19 EGC31364.1 - 1.9e-26 93.0 0.1 3.2e-26 92.2 0.1 1.4 1 0 0 1 1 1 1 SpoU rRNA Methylase family BRCT PF00533.26 EGC31365.1 - 1.2e-11 44.9 2.1 1.2e-11 44.9 2.1 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC31365.1 - 5.8e-09 36.2 2.3 1.2e-08 35.2 0.9 2.3 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC31365.1 - 0.028 14.4 0.1 0.064 13.2 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain DivIC PF04977.15 EGC31365.1 - 5.7 6.8 14.7 6.9 6.5 0.3 3.9 2 1 1 3 3 3 0 Septum formation initiator UCH PF00443.29 EGC31366.1 - 5.8e-46 157.1 1.6 7.8e-46 156.6 1.6 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC31366.1 - 8.6e-21 74.8 1.4 1.6e-20 74.0 1.4 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase EGF_2 PF07974.13 EGC31369.1 - 5.8e-45 151.3 230.1 6.1e-07 29.7 12.7 12.6 10 2 2 12 12 12 12 EGF-like domain Toxin_2 PF00451.19 EGC31369.1 - 0.0016 18.7 9.1 0.0016 18.7 9.1 10.9 12 0 0 12 12 12 1 Scorpion short toxin, BmKK2 SKG6 PF08693.10 EGC31369.1 - 0.01 15.2 0.3 0.02 14.3 0.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain COX4 PF02936.14 EGC31371.1 - 0.00078 19.5 0.0 0.00084 19.4 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit IV Lum_binding PF00677.17 EGC31371.1 - 0.14 12.2 0.0 0.24 11.4 0.0 1.4 1 1 1 2 2 2 0 Lumazine binding domain Cation_efflux PF01545.21 EGC31372.1 - 2.4e-42 144.9 0.2 3e-42 144.6 0.2 1.1 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EGC31372.1 - 0.0013 18.0 13.1 0.0023 17.2 13.1 1.4 1 1 0 1 1 1 1 ZIP Zinc transporter NicO PF03824.16 EGC31372.1 - 0.074 12.4 4.9 0.16 11.3 4.9 1.6 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF3430 PF11912.8 EGC31373.1 - 3.4e-33 115.5 27.8 4.2e-33 115.2 27.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kinesin PF00225.23 EGC31374.1 - 4.9e-56 190.1 6.4 4.9e-56 190.1 6.4 1.6 1 1 1 2 2 2 2 Kinesin motor domain Microtub_bd PF16796.5 EGC31374.1 - 3e-25 88.9 3.7 4.5e-25 88.3 3.7 1.3 1 0 0 1 1 1 1 Microtubule binding ATP-sulfurylase PF01747.17 EGC31374.1 - 0.013 14.9 0.0 0.018 14.5 0.0 1.3 1 0 0 1 1 1 0 ATP-sulfurylase TLP-20 PF06088.11 EGC31375.1 - 0.0019 18.1 0.1 0.0029 17.5 0.1 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sporozoite_P67 PF05642.11 EGC31375.1 - 0.085 10.9 0.7 0.11 10.6 0.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC2_membrane_3 PF12698.7 EGC31376.1 - 2.5e-57 194.5 70.6 1.5e-31 109.8 34.1 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGC31376.1 - 1.9e-52 177.4 0.3 5.7e-25 88.4 0.1 2.8 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC31376.1 - 1.7e-16 60.9 0.3 3.9e-06 26.9 0.0 5.1 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC31376.1 - 2.7e-06 27.0 0.0 0.73 9.2 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 EGC31376.1 - 0.00065 19.4 0.7 0.72 9.5 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGC31376.1 - 0.0013 18.4 2.3 0.042 13.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGC31376.1 - 0.0036 17.5 0.1 1.2 9.4 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.29 EGC31376.1 - 0.015 15.8 0.0 0.78 10.2 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF2374 PF09574.10 EGC31376.1 - 0.019 14.8 0.4 0.019 14.8 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (Duf2374) Rad17 PF03215.15 EGC31376.1 - 0.052 13.5 0.2 4.9 7.0 0.0 3.0 3 0 0 3 3 3 0 Rad17 P-loop domain AAA_23 PF13476.6 EGC31376.1 - 0.054 14.0 11.2 0.51 10.8 0.1 3.4 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGC31376.1 - 0.077 12.9 1.1 3.4 7.5 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EGC31376.1 - 0.24 11.1 0.3 9.1 5.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain EF1G PF00647.19 EGC31377.1 - 5.2e-43 145.5 0.1 1.1e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGC31377.1 - 9e-16 58.0 0.0 9e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC31377.1 - 1e-08 35.3 2.2 1.8e-08 34.5 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC31377.1 - 4.8e-07 30.0 0.0 9.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC31377.1 - 7.6e-06 26.3 0.0 2.4e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC31377.1 - 4e-05 23.5 0.0 9.8e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC31377.1 - 0.00013 22.1 0.0 0.00037 20.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EGC31377.1 - 0.0052 17.1 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC31377.1 - 0.011 15.5 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 EGC31377.1 - 1.7 9.3 5.5 0.7 10.5 2.6 1.8 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Pkinase PF00069.25 EGC31378.1 - 3.1e-34 118.5 0.2 1.4e-33 116.3 0.2 2.0 1 1 0 1 1 1 1 Protein kinase domain RabGAP-TBC PF00566.18 EGC31378.1 - 7.5e-34 117.3 2.4 7.5e-34 117.3 2.4 2.8 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Pkinase_Tyr PF07714.17 EGC31378.1 - 8.3e-16 58.0 0.0 1.6e-14 53.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Rhodanese PF00581.20 EGC31378.1 - 3.2e-05 24.4 0.0 0.00011 22.7 0.0 1.9 1 0 0 1 1 1 1 Rhodanese-like domain DUF3458 PF11940.8 EGC31378.1 - 0.0022 18.4 0.1 0.0085 16.5 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF3458) Ig-like fold Kinase-like PF14531.6 EGC31378.1 - 0.012 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pet127 PF08634.10 EGC31379.1 - 3.2e-85 285.9 0.7 3.2e-85 285.9 0.7 2.7 3 1 1 4 4 4 1 Mitochondrial protein Pet127 GIT_CC PF16559.5 EGC31379.1 - 0.73 9.7 5.2 3.3 7.7 2.0 3.1 2 0 0 2 2 2 0 GIT coiled-coil Rho guanine nucleotide exchange factor RIO1 PF01163.22 EGC31380.1 - 1.5e-49 168.2 0.3 4.8e-49 166.5 0.3 1.9 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.11 EGC31380.1 - 1.9e-32 111.3 0.4 4.4e-32 110.1 0.4 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.23 EGC31380.1 - 6.4e-09 36.1 0.0 0.00057 19.9 0.0 2.7 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGC31380.1 - 8.1e-08 31.9 0.1 4.5e-06 26.2 0.1 2.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family U1snRNP70_N PF12220.8 EGC31380.1 - 0.038 14.6 2.3 0.038 14.6 2.3 2.8 2 1 1 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal SID-1_RNA_chan PF13965.6 EGC31380.1 - 0.44 8.9 1.6 0.7 8.2 1.6 1.5 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RNA_pol_Rpc4 PF05132.14 EGC31380.1 - 1.3 9.4 11.4 0.083 13.3 2.2 2.3 2 0 0 2 2 2 0 RNA polymerase III RPC4 F-box-like PF12937.7 EGC31381.1 - 0.12 12.3 0.0 0.36 10.8 0.0 1.8 1 0 0 1 1 1 0 F-box-like Mucin PF01456.17 EGC31383.1 - 0.41 10.6 14.5 0.69 9.9 14.5 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein EI24 PF07264.11 EGC31384.1 - 0.015 15.6 3.0 0.015 15.6 3.0 1.9 1 1 1 2 2 2 0 Etoposide-induced protein 2.4 (EI24) LrgA PF03788.14 EGC31384.1 - 0.093 12.7 2.2 0.2 11.7 2.2 1.5 1 1 1 2 2 2 0 LrgA family Pkinase PF00069.25 EGC31385.1 - 6.1e-76 255.3 0.0 1e-75 254.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31385.1 - 5.5e-56 189.7 0.0 9.4e-56 189.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC31385.1 - 3.9e-06 25.9 0.0 9.9e-06 24.6 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase YrbL-PhoP_reg PF10707.9 EGC31385.1 - 0.00015 21.4 0.1 0.00039 20.0 0.1 1.7 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.6 EGC31385.1 - 0.0011 18.4 0.1 0.0018 17.6 0.1 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.22 EGC31385.1 - 0.0099 15.5 0.1 0.02 14.5 0.1 1.4 1 0 0 1 1 1 1 RIO1 family SlyX PF04102.12 EGC31385.1 - 0.065 13.9 0.5 0.2 12.3 0.5 1.8 1 0 0 1 1 1 0 SlyX Kdo PF06293.14 EGC31385.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC31385.1 - 0.25 11.2 0.0 19 5.1 0.0 2.4 2 1 1 3 3 3 0 Phosphotransferase enzyme family Occludin_ELL PF07303.13 EGC31385.1 - 0.45 11.3 3.5 0.79 10.5 1.4 2.3 2 0 0 2 2 2 0 Occludin homology domain SR-25 PF10500.9 EGC31385.1 - 2.6 7.6 18.6 4.6 6.8 14.3 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_M41 PF01434.18 EGC31386.1 - 1.3e-66 224.1 0.1 1.9e-66 223.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGC31386.1 - 2.5e-44 150.9 0.0 8.7e-44 149.2 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC31386.1 - 1.6e-15 56.6 0.1 5.1e-15 55.0 0.1 1.9 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC31386.1 - 0.00032 20.7 0.5 0.004 17.1 0.1 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC31386.1 - 0.0012 19.2 0.3 0.2 12.0 0.0 3.0 4 0 0 4 4 4 1 AAA ATPase domain RuvB_N PF05496.12 EGC31386.1 - 0.0016 18.2 0.0 0.0097 15.7 0.0 2.3 3 0 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGC31386.1 - 0.0082 16.7 0.1 0.33 11.5 0.0 2.7 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.6 EGC31386.1 - 0.012 15.9 0.4 0.28 11.4 0.1 2.9 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.6 EGC31386.1 - 0.02 15.3 0.0 0.05 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGC31386.1 - 0.037 13.2 0.0 0.068 12.4 0.0 1.3 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_2 PF07724.14 EGC31386.1 - 0.04 14.0 0.2 0.32 11.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_32 PF13654.6 EGC31386.1 - 0.057 12.2 0.8 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.21 EGC31386.1 - 0.065 12.6 0.1 0.13 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGC31386.1 - 0.077 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Amidohydro_2 PF04909.14 EGC31387.1 - 5.7e-59 200.3 0.0 6.4e-59 200.1 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase Peptidase_M8 PF01457.16 EGC31388.1 - 5.2e-135 451.1 7.3 8.4e-135 450.4 0.3 2.0 1 1 1 2 2 2 2 Leishmanolysin TIG PF01833.24 EGC31388.1 - 1.4e-06 28.3 1.2 5.4e-06 26.4 1.2 2.1 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_M10 PF00413.24 EGC31388.1 - 0.018 14.9 0.1 0.034 14.0 0.1 1.6 1 1 0 1 1 1 0 Matrixin TMEM52 PF14979.6 EGC31388.1 - 0.079 12.9 1.2 0.16 11.9 1.2 1.4 1 0 0 1 1 1 0 Transmembrane 52 Tweety PF04906.13 EGC31388.1 - 0.16 10.6 1.0 0.35 9.5 1.0 1.5 1 0 0 1 1 1 0 Tweety LptF_LptG PF03739.14 EGC31388.1 - 0.65 8.8 5.4 1.2 7.9 5.4 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Menin PF05053.13 EGC31388.1 - 6.5 5.0 10.6 9.5 4.4 10.6 1.1 1 0 0 1 1 1 0 Menin RRM_5 PF13893.6 EGC31389.1 - 3.8e-39 133.1 5.7 1.1e-24 86.4 0.0 4.4 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGC31389.1 - 7.4e-32 109.0 0.6 3.9e-08 33.0 0.2 4.7 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC31389.1 - 6e-08 32.4 2.1 0.61 10.0 0.1 4.6 4 0 0 4 4 4 4 Occluded RNA-recognition motif RRM_8 PF11835.8 EGC31389.1 - 1.6e-07 31.4 0.0 4.2e-07 30.1 0.0 1.7 1 0 0 1 1 1 1 RRM-like domain RL PF17797.1 EGC31389.1 - 0.0015 18.4 10.2 0.33 10.9 0.1 5.0 5 1 1 6 6 6 2 RL domain Cpn60_TCP1 PF00118.24 EGC31390.1 - 2.2e-97 326.7 0.4 3.1e-97 326.2 0.4 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RL10P_insert PF17777.1 EGC31391.1 - 6.8e-19 67.6 0.3 1.7e-18 66.4 0.2 1.8 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P Ribosomal_L10 PF00466.20 EGC31391.1 - 8.5e-19 67.5 1.6 2.1e-18 66.3 1.6 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.19 EGC31391.1 - 2.5e-12 47.2 16.0 6.3e-12 45.9 14.0 2.5 2 1 0 2 2 2 1 60s Acidic ribosomal protein PfkB PF00294.24 EGC31394.1 - 1.1e-09 38.0 0.0 1.8e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase HNH_3 PF13392.6 EGC31396.1 - 3.6e-12 45.9 3.6 3.6e-12 45.9 3.6 1.8 2 0 0 2 2 2 1 HNH endonuclease zf-CCHC_5 PF14787.6 EGC31396.1 - 1.9e-07 30.7 0.3 4e-07 29.6 0.3 1.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 EGC31396.1 - 0.00033 20.6 2.0 0.00061 19.7 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle PfkB PF00294.24 EGC31397.1 - 1.8e-13 50.5 0.0 2e-12 47.1 0.0 2.7 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mob_Pre PF01076.19 EGC31397.1 - 0.013 15.4 0.2 0.02 14.7 0.2 1.3 1 0 0 1 1 1 0 Plasmid recombination enzyme Ras PF00071.22 EGC31398.1 - 3.6e-14 52.7 1.1 4.7e-14 52.3 0.9 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC31398.1 - 1.5e-10 41.3 0.1 2.6e-10 40.6 0.1 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC31398.1 - 0.00037 20.6 0.1 0.00068 19.7 0.1 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase DJ-1_PfpI PF01965.24 EGC31399.1 - 3.7e-11 43.1 0.0 1.3e-10 41.4 0.0 1.8 1 1 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGC31399.1 - 2.2e-05 24.2 0.0 8.9e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 ThiJ/PfpI family-like Rcd1 PF04078.13 EGC31400.1 - 1.3e-115 385.1 0.5 1.6e-115 384.9 0.5 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like MOZART1 PF12554.8 EGC31400.1 - 0.12 12.2 1.4 12 5.7 0.0 3.0 3 0 0 3 3 3 0 Mitotic-spindle organizing gamma-tubulin ring associated RPN13_C PF16550.5 EGC31400.1 - 0.37 11.0 2.3 8.5 6.6 2.3 2.5 1 1 0 1 1 1 0 UCH-binding domain RAI16-like PF10257.9 EGC31401.1 - 2.6e-107 358.8 9.1 2.6e-107 358.8 9.1 2.1 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein XAP5 PF04921.14 EGC31401.1 - 6 6.6 17.9 6.5 6.5 8.2 2.6 2 0 0 2 2 2 0 XAP5, circadian clock regulator GatB_N PF02934.15 EGC31402.1 - 2.4e-102 342.0 0.0 3.6e-102 341.4 0.0 1.3 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.18 EGC31402.1 - 4.6e-35 120.7 0.0 9.3e-35 119.7 0.0 1.6 1 0 0 1 1 1 1 GatB domain DUF4999 PF16390.5 EGC31402.1 - 0.11 12.8 0.2 0.33 11.2 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function MMR_HSR1 PF01926.23 EGC31403.1 - 2.7e-10 40.3 0.2 1.6e-09 37.9 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC31403.1 - 0.00043 19.8 0.1 0.0014 18.1 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.13 EGC31403.1 - 0.0036 16.4 0.0 0.007 15.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) RsgA_GTPase PF03193.16 EGC31403.1 - 0.0086 16.0 0.7 1.7 8.5 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase ANAPC10 PF03256.16 EGC31404.1 - 9.9e-62 207.9 0.0 1.1e-61 207.7 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.13 EGC31404.1 - 0.063 13.5 1.3 0.28 11.4 0.5 2.1 1 1 1 2 2 2 0 PITH domain JmjC PF02373.22 EGC31405.1 - 5e-39 133.3 0.7 2.5e-38 131.0 0.0 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.21 EGC31405.1 - 2.3e-17 63.4 0.0 5.8e-17 62.1 0.0 1.8 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.17 EGC31405.1 - 9.5e-17 60.7 4.4 3.7e-16 58.8 4.4 2.1 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.16 EGC31405.1 - 6.3e-05 23.3 16.8 0.00082 19.7 0.9 2.8 2 0 0 2 2 2 2 C5HC2 zinc finger CDC45 PF02724.14 EGC31405.1 - 0.031 12.6 16.2 0.082 11.2 16.2 1.6 1 0 0 1 1 1 0 CDC45-like protein Jas PF16135.5 EGC31405.1 - 0.053 13.7 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 TPL-binding domain in jasmonate signalling XAF1_C PF18608.1 EGC31405.1 - 0.073 12.6 0.2 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 XIAP-associated factor 1 C-terminal domain YL1 PF05764.13 EGC31405.1 - 0.68 10.0 34.7 0.37 10.9 16.7 3.0 3 0 0 3 3 3 0 YL1 nuclear protein Peptidase_S13 PF02113.15 EGC31406.1 - 3.4e-69 233.7 0.0 4.6e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pentapeptide PF00805.22 EGC31407.1 - 4.6e-29 99.6 24.6 1.1e-11 44.1 4.5 4.0 1 1 0 3 3 3 3 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGC31407.1 - 6.6e-16 58.3 2.3 2e-08 34.3 0.1 2.9 1 1 2 3 3 3 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 EGC31407.1 - 4.9e-14 52.4 0.1 1.1e-13 51.4 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.6 EGC31407.1 - 1.5e-11 44.3 0.1 0.00048 20.2 0.2 3.3 2 1 0 2 2 2 2 Pentapeptide repeats (9 copies) AKAP95 PF04988.12 EGC31407.1 - 0.024 14.9 0.0 0.049 13.9 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Hep_59 PF07052.11 EGC31409.1 - 3e-20 72.9 15.4 3e-20 72.9 15.4 3.1 2 2 1 3 3 3 1 Hepatocellular carcinoma-associated antigen 59 IFT46_B_C PF12317.8 EGC31409.1 - 0.00021 21.1 1.0 0.00021 21.1 1.0 2.2 1 1 1 2 2 2 1 Intraflagellar transport complex B protein 46 C terminal GTP_EFTU_D2 PF03144.25 EGC31409.1 - 0.16 12.4 0.5 0.4 11.1 0.5 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 2 DUF4830 PF16112.5 EGC31409.1 - 0.75 10.3 6.8 2.8 8.5 0.8 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4830) Plk4_PB1 PF18190.1 EGC31409.1 - 1.9 8.7 10.2 0.095 12.9 2.0 2.7 1 1 2 3 3 3 0 Polo-like Kinase 4 Polo Box 1 RRM_1 PF00076.22 EGC31410.1 - 2e-18 66.0 0.2 3.6e-10 39.5 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Apt1 PF10351.9 EGC31410.1 - 0.35 9.7 15.8 0.42 9.4 15.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain RNA_pol_Rpc4 PF05132.14 EGC31410.1 - 0.45 10.9 3.3 24 5.3 5.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 Glycoprot_B_PH1 PF17416.2 EGC31410.1 - 0.54 9.8 7.3 0.068 12.8 0.9 2.0 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B Presenilin PF01080.17 EGC31410.1 - 2.6 6.7 10.9 3.2 6.4 10.9 1.1 1 0 0 1 1 1 0 Presenilin Nucleo_P87 PF07267.11 EGC31411.1 - 0.35 9.7 12.4 0.089 11.6 9.4 1.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus capsid protein P87 RVT_1 PF00078.27 EGC31415.1 - 4.8e-07 29.5 0.0 5.8e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RVT_1 PF00078.27 EGC31416.1 - 1e-07 31.7 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pep3_Vps18 PF05131.14 EGC31418.1 - 2.7e-36 124.6 1.4 6.7e-36 123.4 0.4 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.20 EGC31418.1 - 8.8e-14 51.6 4.6 8.8e-14 51.6 4.6 3.1 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-C3HC4_2 PF13923.6 EGC31418.1 - 6.6e-05 22.7 2.3 0.00018 21.3 2.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC31418.1 - 8.8e-05 22.4 1.8 0.00022 21.1 1.8 1.7 1 0 0 1 1 1 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGC31418.1 - 0.00019 21.0 0.7 0.00019 21.0 0.7 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_2 PF13639.6 EGC31418.1 - 0.00074 19.8 2.1 0.0021 18.3 2.1 1.8 1 0 0 1 1 1 1 Ring finger domain DUF2175 PF09943.9 EGC31418.1 - 0.0056 17.0 0.4 0.028 14.7 0.0 2.4 2 0 0 2 2 1 1 Uncharacterized protein conserved in archaea (DUF2175) zf-RING_11 PF17123.5 EGC31418.1 - 0.0057 16.4 4.1 0.0057 16.4 4.1 2.4 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGC31418.1 - 0.0092 16.0 1.7 0.029 14.4 1.7 1.9 1 0 0 1 1 1 1 RING-type zinc-finger NOG1_N PF17835.1 EGC31418.1 - 0.0097 15.9 0.1 0.039 13.9 0.1 2.0 1 0 0 1 1 1 1 NOG1 N-terminal helical domain zf-C3H2C3 PF17122.5 EGC31418.1 - 0.013 15.5 3.8 0.035 14.1 3.8 1.8 1 0 0 1 1 1 0 Zinc-finger Vps39_2 PF10367.9 EGC31418.1 - 0.021 15.3 0.1 0.086 13.3 0.1 2.2 1 0 0 1 1 1 0 Vacuolar sorting protein 39 domain 2 zf-rbx1 PF12678.7 EGC31418.1 - 0.059 13.7 0.5 0.23 11.8 0.5 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGC31418.1 - 0.063 13.3 0.1 0.16 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zf_RING PF16744.5 EGC31418.1 - 0.064 13.4 1.9 0.12 12.5 0.6 2.2 2 0 0 2 2 2 0 KIAA1045 RING finger zf-C3HC4 PF00097.25 EGC31418.1 - 0.13 12.1 1.5 0.35 10.8 1.5 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGC31418.1 - 3.9 7.8 5.1 12 6.3 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat zf-ZPR1 PF03367.13 EGC31419.1 - 1.5e-106 353.1 1.0 7.6e-54 181.9 0.1 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain HypA PF01155.19 EGC31419.1 - 0.0056 16.7 2.1 0.11 12.5 0.2 2.5 2 0 0 2 2 2 1 Hydrogenase/urease nickel incorporation, metallochaperone, hypA zf-DNL PF05180.12 EGC31419.1 - 0.075 13.0 0.3 17 5.5 0.0 3.0 2 0 0 2 2 2 0 DNL zinc finger CpXC PF14353.6 EGC31419.1 - 0.11 12.5 1.3 20 5.2 0.0 3.1 3 0 0 3 3 3 0 CpXC protein zf-H2C2_2 PF13465.6 EGC31419.1 - 3.4 8.2 9.5 34 5.1 0.1 3.8 4 0 0 4 4 4 0 Zinc-finger double domain zf-AN1 PF01428.16 EGC31419.1 - 6.6 7.0 8.2 19 5.5 0.1 3.4 4 0 0 4 4 4 0 AN1-like Zinc finger Peptidase_S28 PF05577.12 EGC31420.1 - 1.1e-97 327.7 8.4 1.2e-97 327.5 8.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGC31420.1 - 7.6e-06 25.8 0.0 1.4e-05 24.9 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC31420.1 - 0.00069 18.9 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC31420.1 - 0.024 14.1 0.0 0.074 12.5 0.0 1.7 2 0 0 2 2 2 0 Prolyl oligopeptidase family DUF4296 PF14129.6 EGC31420.1 - 0.078 13.6 1.1 0.25 11.9 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4296) Sporozoite_P67 PF05642.11 EGC31421.1 - 0.0078 14.4 5.9 0.01 13.9 5.9 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen Pox_Ag35 PF03286.14 EGC31421.1 - 0.0088 15.8 11.3 0.0088 15.8 11.3 1.7 2 0 0 2 2 2 1 Pox virus Ag35 surface protein NOA36 PF06524.12 EGC31421.1 - 0.014 14.8 6.2 0.024 14.0 6.2 1.4 1 0 0 1 1 1 0 NOA36 protein TRAP_alpha PF03896.16 EGC31421.1 - 0.11 11.7 5.3 0.18 11.0 5.3 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DNA_pol_phi PF04931.13 EGC31421.1 - 0.61 8.1 12.0 0.78 7.8 12.0 1.2 1 0 0 1 1 1 0 DNA polymerase phi DUF913 PF06025.12 EGC31421.1 - 0.85 8.5 3.9 1.1 8.2 3.9 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) CDC45 PF02724.14 EGC31421.1 - 3.3 5.9 11.9 5.1 5.3 11.9 1.3 1 0 0 1 1 1 0 CDC45-like protein YqaJ PF09588.10 EGC31422.1 - 1.5e-13 51.1 0.0 1.9e-13 50.8 0.0 1.0 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-CCHC PF00098.23 EGC31425.1 - 0.001 19.0 1.6 0.0018 18.2 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EGC31425.1 - 0.084 12.6 2.5 0.17 11.7 2.5 1.5 1 0 0 1 1 1 0 C2H2 zinc-finger zf-CCHC_2 PF13696.6 EGC31425.1 - 0.53 10.2 5.2 1.1 9.1 5.2 1.4 1 0 0 1 1 1 0 Zinc knuckle XRN_N PF03159.18 EGC31426.1 - 1.1e-42 146.2 0.0 1.2e-42 146.1 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus Peptidase_C101 PF16218.5 EGC31427.1 - 0.015 14.6 0.1 0.029 13.6 0.1 1.4 1 0 0 1 1 1 0 Peptidase family C101 MGC-24 PF05283.11 EGC31427.1 - 0.08 13.4 4.9 0.21 12.0 4.9 1.7 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin AMP-binding PF00501.28 EGC31428.1 - 1.2e-63 215.2 0.0 1.5e-63 214.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC31428.1 - 4.2e-10 39.4 1.6 1.3e-09 37.8 1.6 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 EGC31429.1 - 1e-12 47.4 0.0 1.3e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme Fer4_NifH PF00142.18 EGC31429.1 - 0.16 11.4 0.5 0.23 10.9 0.5 1.1 1 0 0 1 1 1 0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family WD40 PF00400.32 EGC31430.1 - 1.2e-14 54.4 5.9 0.00078 20.2 0.1 6.3 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC31430.1 - 0.0002 21.6 1.8 0.62 10.4 0.1 4.2 4 0 0 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Alpha_kinase PF02816.18 EGC31431.1 - 1.2e-55 188.5 0.1 2.8e-55 187.3 0.1 1.7 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.32 EGC31431.1 - 5.1e-28 96.7 10.1 1.4e-05 25.8 0.1 7.8 7 0 0 7 7 7 5 WD domain, G-beta repeat WD40_like PF17005.5 EGC31431.1 - 0.00032 20.1 2.1 0.02 14.2 0.2 2.4 2 0 0 2 2 2 2 WD40-like domain Ge1_WD40 PF16529.5 EGC31431.1 - 0.028 13.4 3.6 0.38 9.7 0.0 3.0 1 1 2 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein SOG2 PF10428.9 EGC31431.1 - 0.17 11.0 20.2 0.3 10.3 20.2 1.4 1 0 0 1 1 1 0 RAM signalling pathway protein bZIP_2 PF07716.15 EGC31431.1 - 2.5 8.3 5.0 4.8 7.3 5.0 1.4 1 0 0 1 1 1 0 Basic region leucine zipper RhoGEF PF00621.20 EGC31432.1 - 6.4e-36 124.3 0.8 6.4e-36 124.3 0.8 2.4 2 0 0 2 2 2 1 RhoGEF domain Arm PF00514.23 EGC31432.1 - 3.5e-14 52.3 9.6 0.00026 20.9 0.0 7.7 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat PH PF00169.29 EGC31432.1 - 2.2e-09 37.7 0.6 7.8e-09 36.0 0.6 2.0 1 0 0 1 1 1 1 PH domain KAP PF05804.12 EGC31432.1 - 3.3e-08 32.2 14.9 6.4e-08 31.2 14.9 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) IQ_SEC7_PH PF16453.5 EGC31432.1 - 0.00019 21.4 0.3 0.00064 19.7 0.3 1.9 1 0 0 1 1 1 1 PH domain Arm_2 PF04826.13 EGC31432.1 - 0.00062 19.3 19.3 0.0065 16.0 1.3 4.2 2 2 2 4 4 4 2 Armadillo-like Rab_bind PF16704.5 EGC31432.1 - 0.011 15.7 0.2 3.9 7.6 0.0 3.1 2 0 0 2 2 2 0 Rab binding domain PH_16 PF17838.1 EGC31432.1 - 0.084 12.7 1.3 0.45 10.4 1.3 2.3 1 1 0 1 1 1 0 PH domain Arm_3 PF16186.5 EGC31432.1 - 0.19 11.3 0.9 2.6 7.6 0.1 2.5 2 0 0 2 2 2 0 Atypical Arm repeat PH_10 PF15411.6 EGC31432.1 - 0.31 11.3 2.6 7.1 6.9 2.2 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain MFS_2 PF13347.6 EGC31433.1 - 1.7e-94 316.8 30.4 2.8e-94 316.1 30.4 1.3 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.16 EGC31433.1 - 7e-23 81.1 47.7 1.8e-16 60.0 27.4 2.4 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4519 PF15012.6 EGC31433.1 - 0.4 10.9 2.0 1.2 9.4 2.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Tweety PF04906.13 EGC31435.1 - 0.00062 18.5 0.8 0.027 13.1 1.5 2.1 2 0 0 2 2 2 1 Tweety DUF2753 PF10952.8 EGC31435.1 - 0.038 14.1 0.0 0.087 12.9 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2753) Band_3_cyto PF07565.13 EGC31435.1 - 0.43 10.4 6.0 0.6 9.9 6.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PCRF PF03462.18 EGC31435.1 - 2.1 8.2 10.6 3.5 7.4 10.6 1.4 1 0 0 1 1 1 0 PCRF domain Exonuc_VII_L PF02601.15 EGC31435.1 - 3.8 7.0 10.0 5.3 6.5 10.0 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit LMBR1 PF04791.16 EGC31435.1 - 7 5.4 7.3 12 4.7 7.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF5401 PF17380.2 EGC31435.1 - 9.4 4.2 16.4 13 3.7 16.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) SapB_2 PF03489.17 EGC31436.1 - 3.6e-25 87.7 13.6 3.7e-15 55.7 2.5 3.2 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC31436.1 - 9.7e-19 67.0 10.3 3.3e-10 39.8 5.2 3.8 5 0 0 5 5 5 2 Saposin-like type B, region 1 Uteroglobin PF01099.17 EGC31436.1 - 0.0098 16.2 4.8 0.17 12.3 0.3 3.0 2 1 2 4 4 4 2 Uteroglobin family DUF1514 PF07438.11 EGC31436.1 - 0.088 12.7 0.3 0.15 11.9 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) DUF3456 PF11938.8 EGC31436.1 - 0.17 12.4 6.9 1.7 9.1 0.4 3.2 2 2 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP YyzF PF14116.6 EGC31436.1 - 0.18 11.9 3.0 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 YyzF-like protein FA_desaturase PF00487.24 EGC31437.1 - 9.7e-35 120.6 15.0 1e-34 120.6 13.1 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGC31437.1 - 4.1e-21 74.9 0.0 9.8e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRD PF00874.20 EGC31437.1 - 0.011 16.0 0.0 0.05 13.9 0.0 2.2 1 0 0 1 1 1 0 PRD domain adh_short PF00106.25 EGC31438.1 - 2.5e-41 141.3 0.0 4.4e-41 140.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC31438.1 - 1.4e-24 87.0 0.0 1.9e-24 86.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC31438.1 - 2.5e-11 43.8 0.0 8.8e-09 35.5 0.0 2.2 2 0 0 2 2 2 2 KR domain Sacchrp_dh_NADP PF03435.18 EGC31438.1 - 2.4e-05 24.6 0.0 4.9e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGC31438.1 - 0.0013 19.3 0.0 0.0027 18.2 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.16 EGC31438.1 - 0.025 15.3 0.1 1.3 9.7 0.1 2.7 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Polysacc_synt_2 PF02719.15 EGC31438.1 - 0.07 12.3 0.2 0.3 10.2 0.2 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein Helicase_RecD PF05127.14 EGC31438.1 - 0.083 12.7 0.0 0.18 11.6 0.0 1.6 1 0 0 1 1 1 0 Helicase F5_F8_type_C PF00754.25 EGC31439.1 - 1.5e-23 83.3 0.2 2.6e-23 82.5 0.2 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC31439.1 - 1.2e-20 73.5 0.3 1.2e-20 73.5 0.3 1.9 2 1 0 2 2 2 1 H-type lectin domain ASCH PF04266.14 EGC31440.1 - 8.4e-15 55.3 0.0 9.4e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 ASCH domain SLT PF01464.20 EGC31441.1 - 8.5e-08 31.9 0.0 1.5e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGC31441.1 - 0.00083 19.6 5.3 0.0031 17.7 5.3 1.8 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Rad60-SLD PF11976.8 EGC31442.1 - 1.2e-19 69.9 3.2 4.5e-12 45.6 0.3 3.2 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC31442.1 - 0.00053 19.7 1.3 0.098 12.4 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin family SCHIP-1 PF10148.9 EGC31442.1 - 0.13 11.8 8.9 2.7 7.6 0.0 2.3 2 0 0 2 2 2 0 Schwannomin-interacting protein 1 TPR_2 PF07719.17 EGC31443.1 - 9.2e-13 47.3 0.0 0.0069 16.4 0.0 5.7 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31443.1 - 3.9e-12 45.4 0.0 0.011 15.5 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31443.1 - 7.9e-08 31.9 0.3 0.96 9.8 0.0 5.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31443.1 - 9.1e-07 28.5 0.0 2.4 7.9 0.0 4.7 4 0 0 4 4 4 3 TPR repeat TPR_12 PF13424.6 EGC31443.1 - 5.4e-06 26.6 0.1 0.57 10.5 0.1 4.2 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31443.1 - 0.00072 20.2 0.0 4.9 7.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC31443.1 - 0.005 16.9 0.0 15 5.8 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31443.1 - 0.0066 16.7 0.0 6.7 7.3 0.0 3.3 2 0 0 2 2 2 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31443.1 - 0.046 13.9 3.0 7.5 6.9 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGC31443.1 - 0.087 13.3 0.0 1.6 9.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31443.1 - 0.11 12.5 0.1 14 6.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF5119 PF17145.4 EGC31444.1 - 0.13 12.3 0.1 0.13 12.1 0.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5119) DUF4539 PF15072.6 EGC31445.1 - 9e-26 89.7 0.0 1.8e-25 88.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) LRR_8 PF13855.6 EGC31446.1 - 1.1e-09 37.9 25.5 0.0096 15.7 0.1 6.5 4 3 1 5 5 5 4 Leucine rich repeat LRR_6 PF13516.6 EGC31446.1 - 1.1e-07 31.4 21.4 0.11 12.6 0.1 8.9 9 0 0 9 9 9 4 Leucine Rich repeat STAS PF01740.21 EGC31446.1 - 0.018 14.7 0.1 2.7 7.7 0.1 2.9 3 0 0 3 3 3 0 STAS domain LRR_4 PF12799.7 EGC31446.1 - 0.022 15.2 0.3 0.022 15.2 0.3 9.4 2 1 5 9 9 9 0 Leucine Rich repeats (2 copies) TPT PF03151.16 EGC31447.1 - 7.4e-24 84.6 30.4 9.3e-24 84.3 30.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGC31447.1 - 3.5e-11 43.4 43.5 1.5e-05 25.2 17.2 2.4 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGC31447.1 - 0.00096 18.4 29.9 0.0061 15.8 29.9 2.0 1 1 0 1 1 1 1 UAA transporter family Phage_holin_2_4 PF16082.5 EGC31447.1 - 0.075 12.8 0.2 0.19 11.5 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage holin family, superfamily II-like 7TMR-DISM_7TM PF07695.11 EGC31447.1 - 0.72 9.7 49.9 0.049 13.5 22.6 2.6 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF1003 PF06210.11 EGC31447.1 - 2.3 8.4 6.9 1.3 9.2 3.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF1003) zf-CCCH PF00642.24 EGC31448.1 - 7.3e-12 44.9 12.7 6.1e-07 29.2 1.8 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGC31448.1 - 0.00012 22.0 12.9 0.00035 20.5 1.0 2.5 2 0 0 2 2 2 2 Zinc finger domain RRM_1 PF00076.22 EGC31448.1 - 0.0015 18.3 0.1 0.03 14.1 0.0 2.2 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EGC31448.1 - 0.017 15.8 8.0 0.9 10.3 0.1 3.4 3 0 0 3 3 3 0 Torus domain zf-CCCH_3 PF15663.5 EGC31448.1 - 0.046 13.9 0.1 11 6.3 0.0 2.3 2 0 0 2 2 2 0 Zinc-finger containing family DUF4106 PF13388.6 EGC31448.1 - 5.2 6.2 12.4 9.7 5.3 12.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Rhodanese PF00581.20 EGC31449.1 - 2.1e-08 34.6 0.0 5.3e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Rhodanese-like domain CENP-F_C_Rb_bdg PF10490.9 EGC31449.1 - 0.096 12.1 0.1 19 4.8 0.0 2.6 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 DUF1202 PF06717.11 EGC31449.1 - 0.16 11.3 0.0 0.23 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1202) OPA3 PF07047.12 EGC31450.1 - 6.8e-35 119.6 0.4 8.2e-35 119.3 0.4 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) GSCFA PF08885.11 EGC31450.1 - 0.001 18.7 0.2 0.0013 18.5 0.2 1.0 1 0 0 1 1 1 1 GSCFA family ZapB PF06005.12 EGC31450.1 - 0.037 14.5 0.5 0.037 14.5 0.5 2.1 1 1 1 2 2 2 0 Cell division protein ZapB Holin_BhlA PF10960.8 EGC31450.1 - 0.23 11.5 3.1 0.74 9.8 3.1 1.7 1 1 0 1 1 1 0 BhlA holin family AMP-binding PF00501.28 EGC31451.1 - 3.3e-11 42.4 0.0 2.3e-07 29.8 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Sel1 PF08238.12 EGC31452.1 - 7.5e-16 58.2 2.1 7.8e-06 26.4 0.3 5.1 4 1 0 4 4 4 3 Sel1 repeat TPR_10 PF13374.6 EGC31452.1 - 0.0098 15.7 0.2 3 7.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31452.1 - 0.012 15.6 8.1 0.26 11.5 0.1 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31452.1 - 0.014 15.6 3.2 0.34 11.2 0.1 3.6 2 1 2 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC31452.1 - 0.026 15.2 2.3 3.9 8.3 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat OmdA PF13376.6 EGC31452.1 - 0.03 14.3 0.2 0.17 11.9 0.0 2.3 2 0 0 2 2 2 0 Bacteriocin-protection, YdeI or OmpD-Associated TPR_3 PF07720.12 EGC31452.1 - 0.057 13.4 0.4 0.057 13.4 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31452.1 - 0.069 13.4 0.1 1.7 9.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31452.1 - 8.5 6.4 9.4 8 6.5 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SNARE_assoc PF09335.11 EGC31453.1 - 2.1e-08 34.6 0.0 2.1e-08 34.6 0.0 2.8 2 1 1 3 3 3 1 SNARE associated Golgi protein OATP PF03137.20 EGC31453.1 - 3.5e-05 22.3 1.7 0.00022 19.7 0.1 2.1 2 0 0 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family PRA1 PF03208.19 EGC31454.1 - 1e-29 103.0 5.3 1.1e-29 102.9 5.3 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF2070 PF09843.9 EGC31454.1 - 0.098 10.9 10.1 0.11 10.7 10.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF5366 PF17328.2 EGC31454.1 - 0.16 12.1 16.2 0.24 11.5 15.9 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5366) DPM3 PF08285.11 EGC31454.1 - 6.8 7.0 7.2 20 5.4 6.1 2.2 1 1 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) HEM4 PF02602.15 EGC31455.1 - 4e-24 85.3 0.0 5.8e-24 84.7 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TPR_17 PF13431.6 EGC31455.1 - 9.5e-09 35.0 3.6 0.0075 16.6 0.1 5.0 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31455.1 - 1.1e-08 35.2 0.8 0.069 14.0 0.1 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31455.1 - 9.9e-08 32.4 1.4 0.012 16.1 0.0 3.2 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31455.1 - 2e-07 30.6 7.6 0.68 10.2 1.0 4.7 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31455.1 - 1.7e-06 28.6 0.2 0.002 18.8 0.0 2.7 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31455.1 - 7.8e-06 25.7 7.5 1.2 9.5 0.1 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31455.1 - 0.00027 21.2 2.4 0.035 14.4 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat SLS PF14611.6 EGC31455.1 - 0.0031 17.4 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator PPR PF01535.20 EGC31455.1 - 0.067 13.5 0.0 1.7 9.0 0.0 3.0 2 0 0 2 2 2 0 PPR repeat ANAPC3 PF12895.7 EGC31455.1 - 0.099 12.9 2.6 5 7.4 0.6 3.3 1 1 2 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Mad3_BUB1_I PF08311.12 EGC31455.1 - 0.15 12.1 3.8 2.1 8.3 0.1 3.7 3 1 0 3 3 3 0 Mad3/BUB1 homology region 1 TPR_1 PF00515.28 EGC31455.1 - 4.8 7.2 9.9 17 5.5 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyclin_N PF00134.23 EGC31456.1 - 6e-13 48.7 1.2 9.8e-13 48.0 1.2 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-HIT PF04438.16 EGC31457.1 - 2.4e-07 30.5 17.6 3.7e-07 29.9 17.6 1.3 1 0 0 1 1 1 1 HIT zinc finger HECT PF00632.25 EGC31458.1 - 7e-101 337.7 0.1 1.1e-100 337.2 0.1 1.3 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) DUF3885 PF13021.6 EGC31458.1 - 0.036 14.2 0.2 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) LCM PF04072.14 EGC31459.1 - 1.3e-31 110.0 0.1 6.5e-31 107.7 0.0 2.1 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Activator_LAG-3 PF11498.8 EGC31459.1 - 1.7 7.5 28.5 3.6 6.5 28.5 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ras PF00071.22 EGC31461.1 - 4.9e-37 127.0 0.0 5.7e-37 126.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31461.1 - 1.1e-18 67.6 0.0 2.6e-18 66.4 0.0 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31461.1 - 9.3e-05 22.0 0.0 0.00012 21.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGC31461.1 - 0.0078 16.1 0.3 2.2 8.2 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase TPK_catalytic PF04263.16 EGC31461.1 - 0.014 15.5 0.1 0.029 14.4 0.1 1.5 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain Septin PF00735.18 EGC31461.1 - 0.023 14.0 0.0 0.042 13.1 0.0 1.4 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.23 EGC31461.1 - 0.037 14.1 0.0 0.066 13.3 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Mic1 PF07035.12 EGC31461.1 - 0.1 12.3 0.1 0.16 11.7 0.1 1.3 1 0 0 1 1 1 0 Colon cancer-associated protein Mic1-like DUF2528 PF10800.8 EGC31462.1 - 0.077 13.6 0.4 0.29 11.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2528) MOLO1 PF17175.4 EGC31462.1 - 0.1 12.7 0.3 0.56 10.3 0.3 2.3 1 0 0 1 1 1 0 Modulator of levamisole receptor-1 ABC2_membrane_3 PF12698.7 EGC31463.1 - 0.037 13.1 0.3 0.05 12.7 0.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein adh_short PF00106.25 EGC31464.1 - 9.6e-37 126.3 0.0 1.4e-36 125.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC31464.1 - 9.3e-27 94.1 0.0 1.2e-26 93.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC31464.1 - 1.9e-05 24.7 0.0 2.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC31464.1 - 0.0014 18.1 0.0 0.0025 17.3 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGC31464.1 - 0.0049 16.3 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EGC31464.1 - 0.0065 15.9 0.1 0.0095 15.4 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC31464.1 - 0.12 12.3 0.0 0.16 11.9 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding Streptin-Immun PF11083.8 EGC31464.1 - 0.55 10.7 5.8 0.39 11.2 0.2 2.9 3 1 0 3 3 3 0 Lantibiotic streptin immunity protein DUF5093 PF17011.5 EGC31466.1 - 0.016 15.5 0.5 0.08 13.2 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5093) Cas9_PI2 PF18070.1 EGC31467.1 - 0.48 11.2 7.7 4.5 8.1 0.4 3.4 4 0 0 4 4 4 0 CRISPR-Cas9 PI domain BAR_3 PF16746.5 EGC31468.1 - 1.5e-06 28.1 23.8 2.5e-06 27.4 20.7 2.5 2 1 0 2 2 2 1 BAR domain of APPL family RasGAP PF00616.19 EGC31468.1 - 0.0051 16.5 0.3 0.0051 16.5 0.3 4.7 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase PucR PF07905.11 EGC31468.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family Ta0938 PF11494.8 EGC31468.1 - 0.44 10.8 3.2 1.3 9.3 3.2 1.8 1 0 0 1 1 1 0 Ta0938 Occludin_ELL PF07303.13 EGC31468.1 - 8.3 7.2 19.1 1.9 9.3 7.2 3.3 3 0 0 3 3 3 0 Occludin homology domain CLU PF13236.6 EGC31469.1 - 9e-51 172.8 1.2 4.6e-50 170.5 0.0 2.6 3 0 0 3 3 3 1 Clustered mitochondria TPR_12 PF13424.6 EGC31469.1 - 6.4e-39 132.1 1.0 1.3e-10 41.5 0.0 5.9 2 1 5 7 7 7 7 Tetratricopeptide repeat TPR_10 PF13374.6 EGC31469.1 - 1.5e-14 53.3 0.1 0.013 15.4 0.0 6.4 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31469.1 - 2.5e-08 33.4 1.0 0.015 15.4 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31469.1 - 1.6e-07 30.8 6.4 0.014 15.2 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31469.1 - 2.8e-07 30.2 8.1 0.0061 16.7 0.3 5.8 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31469.1 - 2.7e-06 27.0 0.6 0.022 14.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGC31469.1 - 3.1e-06 27.3 0.1 3.1e-06 27.3 0.1 2.8 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 TPR_MalT PF17874.1 EGC31469.1 - 0.007 15.8 0.0 0.037 13.4 0.0 1.9 1 1 1 2 2 2 1 MalT-like TPR region Synaptobrevin PF00957.21 EGC31469.1 - 0.066 13.0 1.6 1.3 8.9 0.7 3.3 3 0 0 3 3 3 0 Synaptobrevin PBD PF00786.28 EGC31469.1 - 0.098 13.0 0.0 0.6 10.5 0.0 2.4 1 0 0 1 1 1 0 P21-Rho-binding domain TPR_11 PF13414.6 EGC31469.1 - 0.11 12.2 0.8 2.2 8.0 0.3 2.8 2 0 0 2 2 2 0 TPR repeat ADP_ribosyl_GH PF03747.14 EGC31470.1 - 1.4e-36 126.7 0.0 1.7e-36 126.5 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Pox_A14 PF05767.12 EGC31471.1 - 0.03 14.5 1.0 0.038 14.2 1.0 1.3 1 0 0 1 1 1 0 Poxvirus virion envelope protein A14 STE2 PF02116.15 EGC31471.1 - 0.03 13.6 0.8 0.036 13.4 0.8 1.1 1 0 0 1 1 1 0 Fungal pheromone mating factor STE2 GPCR YesK PF14150.6 EGC31471.1 - 0.14 12.4 5.0 0.18 12.0 5.0 1.2 1 0 0 1 1 1 0 YesK-like protein YrhC PF14143.6 EGC31471.1 - 0.52 10.4 6.0 1.4 9.1 1.4 2.3 2 0 0 2 2 2 0 YrhC-like protein DUF1548 PF07579.11 EGC31472.1 - 0.12 12.7 2.9 5.2 7.4 0.1 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1548) DDA1 PF10172.9 EGC31473.1 - 1.4e-08 34.9 0.3 1.4e-08 34.9 0.3 2.1 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase GxGYxYP_C PF14323.6 EGC31473.1 - 0.41 10.5 2.9 0.48 10.3 2.9 1.1 1 0 0 1 1 1 0 GxGYxYP putative glycoside hydrolase C-terminal domain Profilin PF00235.19 EGC31474.1 - 1.5e-16 60.8 1.2 2.1e-16 60.3 1.2 1.2 1 0 0 1 1 1 1 Profilin sCache_like PF16736.5 EGC31474.1 - 0.0071 16.4 0.4 0.015 15.4 0.4 1.5 1 0 0 1 1 1 1 Single Cache-like DUF3198 PF11433.8 EGC31474.1 - 0.13 12.2 1.5 0.26 11.2 1.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3198) Actin PF00022.19 EGC31475.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin zf-C3HC4_3 PF13920.6 EGC31476.1 - 7.1e-08 32.2 6.2 1.1e-07 31.6 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC31476.1 - 8e-06 26.1 7.8 1.3e-05 25.5 7.8 1.3 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 EGC31476.1 - 0.00018 21.7 10.8 0.0002 21.5 10.8 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.6 EGC31476.1 - 0.00018 21.2 7.8 0.00032 20.5 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31476.1 - 0.00037 20.3 8.6 0.00083 19.2 8.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC31476.1 - 0.00039 20.2 8.5 0.0013 18.6 8.6 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC31476.1 - 0.0006 19.7 8.0 0.0011 18.9 8.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGC31476.1 - 0.0024 18.1 4.8 0.0064 16.8 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC31476.1 - 0.0039 17.2 3.6 0.012 15.6 3.6 1.9 1 1 0 1 1 1 1 RING-type zinc-finger NCKAP5 PF15246.6 EGC31476.1 - 0.0097 15.6 8.0 0.011 15.3 8.0 1.1 1 0 0 1 1 1 1 Nck-associated protein 5, Peripheral clock protein Ndc1_Nup PF09531.10 EGC31476.1 - 0.016 13.9 2.0 0.021 13.5 2.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-C3HC4_4 PF15227.6 EGC31476.1 - 0.11 12.7 7.8 0.91 9.7 8.1 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Neur_chan_memb PF02932.16 EGC31476.1 - 0.16 12.0 1.8 0.24 11.4 1.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3381 PF11861.8 EGC31476.1 - 0.18 11.6 9.9 0.28 11.0 9.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) LapA_dom PF06305.11 EGC31476.1 - 0.32 10.8 1.5 1.2 9.0 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DZR PF12773.7 EGC31476.1 - 0.37 10.9 4.1 0.72 9.9 4.1 1.4 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EGC31476.1 - 0.61 9.8 6.6 1.3 8.7 6.6 1.5 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGC31476.1 - 0.75 9.9 7.2 0.19 11.8 3.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC31476.1 - 0.8 9.5 8.4 0.25 11.2 4.5 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain Hexapep PF00132.24 EGC31477.1 - 1.3e-07 31.0 14.8 0.0004 20.0 0.6 4.2 2 2 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.12 EGC31477.1 - 0.00093 18.2 1.8 0.00093 18.2 1.8 1.6 1 1 1 2 2 2 1 L-fucokinase Hexapep_2 PF14602.6 EGC31477.1 - 0.96 9.3 18.2 0.07 12.9 6.3 3.6 2 2 1 3 3 3 0 Hexapeptide repeat of succinyl-transferase IucA_IucC PF04183.12 EGC31478.1 - 7.1e-53 179.6 0.0 1.1e-52 179.0 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.12 EGC31478.1 - 4.2e-16 59.8 0.0 3.5e-15 56.8 0.0 2.1 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter CRAL_TRIO PF00650.20 EGC31478.1 - 0.032 14.0 1.6 0.37 10.5 0.1 2.8 2 0 0 2 2 2 0 CRAL/TRIO domain Acetyltransf_1 PF00583.25 EGC31479.1 - 8.4e-15 55.0 0.1 1.1e-14 54.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC31479.1 - 3.9e-07 30.4 0.1 6.1e-07 29.8 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC31479.1 - 6.9e-06 26.0 0.0 1e-05 25.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC31479.1 - 4.8e-05 24.0 0.0 7.3e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC31479.1 - 0.00036 20.7 0.1 0.00046 20.4 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC31479.1 - 0.00097 19.1 0.0 0.0015 18.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGC31479.1 - 0.02 15.0 0.0 0.046 13.8 0.0 1.6 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Pkinase_Tyr PF07714.17 EGC31480.1 - 7.8e-56 189.2 0.0 4.7e-55 186.7 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC31480.1 - 1e-53 182.4 0.0 1.9e-53 181.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EGC31480.1 - 2.1e-24 85.9 11.5 4.2e-11 43.3 0.4 4.1 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC31480.1 - 2.3e-14 53.5 6.2 1.5e-06 28.6 0.2 5.6 2 1 4 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC31480.1 - 1.7e-13 50.5 4.3 6.1e-06 26.4 0.1 5.4 3 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC31480.1 - 7.3e-10 38.2 6.5 0.0032 17.9 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat Ank PF00023.30 EGC31480.1 - 1.5e-06 28.3 9.6 0.00062 20.1 0.4 5.6 6 0 0 6 6 6 2 Ankyrin repeat Kinase-like PF14531.6 EGC31480.1 - 0.022 14.1 0.0 0.039 13.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGC31480.1 - 0.029 14.3 0.0 0.048 13.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sod_Cu PF00080.20 EGC31481.1 - 2.6e-44 150.8 3.3 3e-44 150.6 3.3 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) RT_RNaseH PF17917.1 EGC31482.1 - 9.1e-06 25.9 0.3 3.4e-05 24.1 0.3 1.8 1 1 0 1 1 1 1 RNase H-like domain found in reverse transcriptase PHD PF00628.29 EGC31483.1 - 4.3e-14 52.1 26.4 2.6e-06 27.2 5.0 3.8 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H_2 PF13832.6 EGC31483.1 - 1.3e-08 34.9 26.7 0.0029 17.7 2.2 3.7 1 1 2 3 3 3 3 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGC31483.1 - 3.7e-08 33.5 37.5 0.00015 21.9 2.5 4.0 2 1 2 4 4 4 3 PHD-like zinc-binding domain PHD_4 PF16866.5 EGC31483.1 - 2.4 8.3 25.6 0.54 10.4 6.6 4.7 2 2 1 3 3 3 0 PHD-finger TonB_N PF16031.5 EGC31484.1 - 0.00038 21.0 10.9 0.00038 21.0 10.9 3.4 3 0 0 3 3 3 2 TonB polyproline region Trypan_PARP PF05887.11 EGC31484.1 - 0.0016 18.4 10.4 0.0016 18.4 10.4 3.2 3 0 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) Nucleoporin_FG PF13634.6 EGC31484.1 - 0.47 11.3 47.1 4.7 8.1 18.0 3.1 1 1 1 2 2 2 0 Nucleoporin FG repeat region HNH_3 PF13392.6 EGC31486.1 - 2.4e-10 40.0 1.6 3.3e-10 39.6 1.6 1.2 1 0 0 1 1 1 1 HNH endonuclease DDE_Tnp_4 PF13359.6 EGC31487.1 - 2.9e-11 43.3 0.0 4e-11 42.8 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC31487.1 - 0.0054 16.4 0.5 0.016 14.9 0.5 1.8 1 1 0 1 1 1 1 Transposase DDE domain B-block_TFIIIC PF04182.12 EGC31487.1 - 0.05 13.8 0.0 0.095 12.9 0.0 1.4 1 0 0 1 1 1 0 B-block binding subunit of TFIIIC DUF3430 PF11912.8 EGC31489.1 - 3.6e-30 105.6 25.5 3.6e-30 105.6 25.5 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) zf-RING_2 PF13639.6 EGC31492.1 - 1.2e-11 44.7 8.8 2e-11 44.0 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC31492.1 - 1.5e-08 34.4 6.6 2.3e-08 33.8 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31492.1 - 4.8e-08 32.7 8.5 8.2e-08 32.0 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31492.1 - 5.5e-08 33.0 6.9 1.6e-07 31.5 6.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC31492.1 - 7.4e-08 32.1 10.4 1.4e-07 31.2 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC31492.1 - 2.4e-06 27.5 2.9 3.9e-06 26.8 1.4 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC31492.1 - 3.1e-06 27.1 9.1 5.6e-06 26.2 9.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC31492.1 - 3.1e-06 26.9 5.2 6.1e-06 26.0 5.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC31492.1 - 0.0012 18.9 9.2 0.0025 17.9 8.4 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC31492.1 - 0.0041 16.9 10.9 0.008 15.9 10.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC31492.1 - 0.0052 16.8 2.2 0.013 15.5 2.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC31492.1 - 0.019 15.1 3.3 0.042 14.0 3.3 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 ODV-E18 PF10717.9 EGC31492.1 - 0.11 12.4 2.2 0.27 11.1 2.2 1.6 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 zf-RING_11 PF17123.5 EGC31492.1 - 0.2 11.4 5.3 0.4 10.5 5.3 1.5 1 0 0 1 1 1 0 RING-like zinc finger DUF4017 PF13209.6 EGC31492.1 - 0.44 10.5 1.7 0.7 9.9 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4017) Zn_ribbon_17 PF17120.5 EGC31492.1 - 0.59 9.8 7.0 0.95 9.1 7.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type PA26 PF04636.13 EGC31492.1 - 0.69 8.8 21.3 1.5 7.6 3.0 2.6 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) UPF0242 PF06785.11 EGC31492.1 - 1.3 9.1 36.3 0.21 11.7 4.3 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF1272 PF06906.11 EGC31492.1 - 4.5 7.4 8.1 8.8 6.5 8.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Citrate_synt PF00285.21 EGC31493.1 - 3e-137 457.5 0.0 3.7e-137 457.2 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Dehalogenase PF13486.6 EGC31494.1 - 0.032 13.6 0.1 0.058 12.8 0.1 1.4 1 0 0 1 1 1 0 Reductive dehalogenase subunit MRC1 PF09444.10 EGC31494.1 - 7.8 7.0 12.1 26 5.3 8.1 2.7 2 0 0 2 2 2 0 MRC1-like domain Chlam_PMP PF02415.17 EGC31496.1 - 0.002 18.5 62.4 0.27 11.8 4.4 9.2 9 0 0 9 9 9 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SKG6 PF08693.10 EGC31496.1 - 0.085 12.3 0.0 0.23 10.9 0.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain zf-UBR PF02207.20 EGC31497.1 - 6.7e-14 51.8 18.8 2.4e-13 50.0 18.8 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF3439 PF11921.8 EGC31497.1 - 0.009 16.0 8.0 0.022 14.7 8.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGC31497.1 - 0.74 7.9 13.0 1.6 6.9 13.0 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC31497.1 - 2.7 8.0 18.9 4.9 7.1 18.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGEF PF00621.20 EGC31498.1 - 5.3e-40 137.6 8.0 5.3e-40 137.6 8.0 5.2 3 1 0 3 3 3 1 RhoGEF domain F-box-like PF12937.7 EGC31499.1 - 7.3e-05 22.6 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 F-box-like BTK PF00779.19 EGC31499.1 - 0.0027 17.5 2.9 0.0027 17.5 2.9 1.9 2 0 0 2 2 2 1 BTK motif F-box PF00646.33 EGC31499.1 - 0.028 14.3 0.1 0.069 13.1 0.1 1.7 1 0 0 1 1 1 0 F-box domain Elongin_A PF06881.11 EGC31499.1 - 0.35 11.4 2.9 0.68 10.5 2.9 1.4 1 0 0 1 1 1 0 RNA polymerase II transcription factor SIII (Elongin) subunit A RNA_polI_A34 PF08208.11 EGC31500.1 - 2.7e-22 79.9 35.7 2.7e-22 79.9 35.7 3.0 1 1 2 3 3 3 1 DNA-directed RNA polymerase I subunit RPA34.5 AF-4 PF05110.13 EGC31500.1 - 1.3 7.0 67.6 1.5 6.8 67.6 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Macoilin PF09726.9 EGC31500.1 - 2.1 6.8 52.8 2.8 6.4 52.8 1.2 1 0 0 1 1 1 0 Macoilin family BAR PF03114.18 EGC31501.1 - 5.9e-10 39.2 12.1 1e-09 38.4 12.1 1.3 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGC31501.1 - 2.3e-08 34.0 11.2 4.8e-08 33.0 11.2 1.4 1 0 0 1 1 1 1 BAR domain of APPL family SOG2 PF10428.9 EGC31501.1 - 0.0011 18.3 16.8 0.0015 17.8 16.8 1.3 1 1 0 1 1 1 1 RAM signalling pathway protein DUF4047 PF13256.6 EGC31501.1 - 0.37 11.0 8.1 0.17 12.1 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4047) GGACT PF06094.12 EGC31503.1 - 1.1e-07 32.5 0.1 1.1e-05 26.0 0.1 2.2 1 1 0 1 1 1 1 Gamma-glutamyl cyclotransferase, AIG2-like AAA PF00004.29 EGC31505.1 - 2.2e-39 134.9 0.0 3.2e-39 134.4 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC31505.1 - 7.7e-08 32.0 0.0 2.2e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGC31505.1 - 3.3e-06 26.9 0.0 1.7e-05 24.6 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC31505.1 - 1.6e-05 25.2 0.2 0.04 14.2 0.0 2.8 2 1 1 3 3 3 2 AAA domain AAA_2 PF07724.14 EGC31505.1 - 8.3e-05 22.8 0.0 0.00017 21.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGC31505.1 - 0.0002 21.8 0.0 0.011 16.2 0.0 2.5 1 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGC31505.1 - 0.00021 21.3 0.0 0.00096 19.2 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC31505.1 - 0.00032 20.7 0.1 0.011 15.7 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGC31505.1 - 0.0008 19.6 0.0 0.0011 19.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC31505.1 - 0.0015 19.1 0.0 0.0026 18.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.21 EGC31505.1 - 0.0027 17.1 0.1 0.0052 16.2 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Hydin_ADK PF17213.3 EGC31505.1 - 0.0028 18.0 0.0 0.0047 17.2 0.0 1.4 1 1 0 1 1 1 1 Hydin Adenylate kinase-like domain TniB PF05621.11 EGC31505.1 - 0.004 16.6 0.1 0.61 9.5 0.0 2.5 2 1 0 2 2 2 1 Bacterial TniB protein RNA_helicase PF00910.22 EGC31505.1 - 0.0059 17.0 0.0 0.014 15.8 0.0 1.8 1 1 0 1 1 1 1 RNA helicase IstB_IS21 PF01695.17 EGC31505.1 - 0.0061 16.3 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.15 EGC31505.1 - 0.0091 16.0 0.1 0.015 15.3 0.1 1.6 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Parvo_NS1 PF01057.17 EGC31505.1 - 0.01 14.9 0.0 0.016 14.4 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_7 PF12775.7 EGC31505.1 - 0.022 14.3 0.1 0.091 12.3 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGC31505.1 - 0.025 14.3 0.0 0.12 12.1 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.6 EGC31505.1 - 0.029 14.6 0.0 0.06 13.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TIP49 PF06068.13 EGC31505.1 - 0.034 13.3 0.1 0.12 11.6 0.0 1.7 1 1 1 2 2 2 0 TIP49 P-loop domain AAA_11 PF13086.6 EGC31505.1 - 0.036 13.8 0.1 0.056 13.2 0.1 1.3 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGC31505.1 - 0.054 13.2 0.2 0.13 12.0 0.2 1.6 1 1 0 1 1 1 0 AAA domain SKI PF01202.22 EGC31505.1 - 0.065 13.4 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate kinase IPT PF01745.16 EGC31505.1 - 0.068 12.6 0.0 0.67 9.3 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_30 PF13604.6 EGC31505.1 - 0.072 12.8 0.4 0.2 11.3 0.4 1.8 1 1 0 1 1 1 0 AAA domain TsaE PF02367.17 EGC31505.1 - 0.091 12.8 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_25 PF13481.6 EGC31505.1 - 0.097 12.2 0.0 1.8 8.1 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGC31505.1 - 0.098 12.6 0.1 0.31 10.9 0.0 1.8 2 0 0 2 2 2 0 NACHT domain ATPase PF06745.13 EGC31505.1 - 0.099 12.0 0.0 1.8 7.8 0.0 2.2 2 0 0 2 2 2 0 KaiC SAP30_Sin3_bdg PF13867.6 EGC31505.1 - 0.1 12.9 0.2 0.52 10.7 0.1 2.1 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 AAA_3 PF07726.11 EGC31505.1 - 0.11 12.3 0.0 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Frataxin_Cyay PF01491.16 EGC31506.1 - 1.6e-32 111.8 0.4 4.5e-32 110.3 0.0 1.7 2 0 0 2 2 2 1 Frataxin-like domain NTPase_P4 PF11602.8 EGC31506.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 zf-TRAF PF02176.18 EGC31507.1 - 3e-19 69.4 15.9 5e-14 52.7 5.5 4.2 2 1 3 5 5 5 4 TRAF-type zinc finger Sina PF03145.16 EGC31507.1 - 1.6e-06 28.2 15.2 0.00019 21.4 6.8 4.0 2 1 2 4 4 4 3 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGC31507.1 - 1.1e-05 25.1 11.0 1.1e-05 25.1 11.0 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31507.1 - 8.5e-05 22.3 13.4 8.5e-05 22.3 13.4 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC31507.1 - 0.0029 18.0 8.4 0.0029 18.0 8.4 3.6 1 1 2 3 3 3 2 TRAF-like zinc-finger MATH PF00917.26 EGC31507.1 - 0.0033 17.5 1.8 0.0033 17.5 1.8 2.2 2 0 0 2 2 2 1 MATH domain MnmE_helical PF12631.7 EGC31507.1 - 0.0074 16.5 0.2 0.012 15.7 0.2 1.3 1 0 0 1 1 1 1 MnmE helical domain zf_UBZ PF18439.1 EGC31507.1 - 0.15 11.7 0.1 0.15 11.7 0.1 5.0 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger Med9 PF07544.13 EGC31507.1 - 0.35 11.0 5.1 0.94 9.6 4.0 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 zf_C2HC_14 PF18574.1 EGC31507.1 - 2.6 7.9 20.9 0.71 9.7 0.8 5.2 5 0 0 5 5 5 0 C2HC Zing finger domain zf-TRAF PF02176.18 EGC31508.1 - 3.5e-12 46.8 6.3 3.5e-12 46.8 6.3 4.0 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC31508.1 - 1.1e-05 25.2 11.8 1.1e-05 25.2 11.8 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31508.1 - 0.00013 21.7 13.7 0.00013 21.7 13.7 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.26 EGC31508.1 - 0.0021 18.2 1.3 0.0021 18.2 1.3 2.8 3 1 0 3 3 3 1 MATH domain zf-TRAF_2 PF15965.5 EGC31508.1 - 0.01 16.3 10.2 0.01 16.3 10.2 4.0 1 1 3 4 4 4 0 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC31508.1 - 0.018 15.4 13.0 0.018 15.4 13.0 3.6 3 0 0 3 3 3 0 Ring finger domain Sina PF03145.16 EGC31508.1 - 0.047 13.6 0.1 0.047 13.6 0.1 3.9 2 1 2 4 4 4 0 Seven in absentia protein family zf_C2HC_14 PF18574.1 EGC31508.1 - 7.6 6.4 0.0 7.6 6.4 0.0 5.9 4 1 2 6 6 6 0 C2HC Zing finger domain zf-TRAF PF02176.18 EGC31509.1 - 2.9e-17 63.1 16.9 1.8e-14 54.2 7.1 4.5 2 1 3 5 5 5 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC31509.1 - 1.8e-06 27.7 11.0 1.8e-06 27.7 11.0 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.26 EGC31509.1 - 5.5e-05 23.3 2.1 5.5e-05 23.3 2.1 2.2 2 0 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.6 EGC31509.1 - 0.00012 21.8 13.3 0.00012 21.8 13.3 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC31509.1 - 0.0021 18.1 10.4 0.0078 16.2 3.6 3.8 2 1 2 4 4 4 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC31509.1 - 0.012 16.1 9.9 0.012 16.1 9.9 3.5 1 1 2 3 3 3 0 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC31509.1 - 0.025 14.9 12.4 0.025 14.9 12.4 3.6 3 2 0 3 3 3 0 Ring finger domain Fucose_iso_N2 PF07882.12 EGC31509.1 - 0.088 12.4 0.5 0.19 11.3 0.5 1.5 1 0 0 1 1 1 0 L-fucose isomerase, second N-terminal domain CENP-H PF05837.12 EGC31509.1 - 0.62 10.5 3.3 0.3 11.5 0.5 1.9 2 0 0 2 2 2 0 Centromere protein H (CENP-H) zf-TRAF PF02176.18 EGC31510.1 - 3.4e-19 69.3 18.2 2e-13 50.8 6.9 4.7 3 1 3 6 6 6 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC31510.1 - 9.4e-07 28.6 12.4 9.4e-07 28.6 12.4 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31510.1 - 9.2e-05 22.2 13.7 9.2e-05 22.2 13.7 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC31510.1 - 0.00058 19.9 2.6 0.00058 19.9 2.6 3.6 2 1 2 4 4 4 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC31510.1 - 0.0012 19.3 8.6 0.0012 19.3 8.6 3.6 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC31510.1 - 0.0099 16.2 13.1 0.0099 16.2 13.1 3.8 3 1 2 5 5 5 1 Ring finger domain CENP-H PF05837.12 EGC31510.1 - 0.4 11.1 5.5 0.072 13.5 1.2 2.0 2 0 0 2 2 2 0 Centromere protein H (CENP-H) zf_C2HC_14 PF18574.1 EGC31510.1 - 2.9 7.8 0.0 2.9 7.8 0.0 5.8 6 0 0 6 6 6 0 C2HC Zing finger domain PBECR1 PF18809.1 EGC31510.1 - 6.3 7.5 10.1 3.1 8.5 7.4 2.0 2 1 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 zf-TRAF PF02176.18 EGC31511.1 - 2.6e-17 63.3 15.3 7.9e-13 48.9 7.2 4.0 2 1 2 4 4 3 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC31511.1 - 0.0001 22.1 11.2 0.0001 22.1 11.2 3.8 3 1 1 4 4 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31511.1 - 0.0033 17.2 13.5 0.0033 17.2 13.5 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Transgly PF00912.22 EGC31511.1 - 0.0098 15.4 1.6 1.2 8.5 0.1 2.3 1 1 1 2 2 2 2 Transglycosylase Sina PF03145.16 EGC31511.1 - 0.021 14.8 0.3 0.021 14.8 0.3 4.3 3 1 2 5 5 4 0 Seven in absentia protein family zf-RING_2 PF13639.6 EGC31511.1 - 0.022 15.1 13.0 0.022 15.1 13.0 3.8 4 0 0 4 4 4 0 Ring finger domain Suppressor_APC PF11414.8 EGC31511.1 - 0.032 14.3 0.0 14 5.8 0.0 2.6 2 0 0 2 2 2 0 Adenomatous polyposis coli tumour suppressor protein DUF826 PF05696.11 EGC31511.1 - 0.055 13.6 0.8 14 5.9 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF826) zf-TRAF_2 PF15965.5 EGC31511.1 - 0.98 9.9 37.6 0.1 13.1 10.4 3.6 1 1 2 3 3 2 0 TRAF-like zinc-finger zf_C2HC_14 PF18574.1 EGC31511.1 - 5.2 6.9 0.0 5.2 6.9 0.0 5.1 5 0 0 5 5 5 0 C2HC Zing finger domain TRPM_tetra PF16519.5 EGC31511.1 - 7.9 6.7 8.0 22 5.3 0.1 3.7 3 1 0 3 3 3 0 Tetramerisation domain of TRPM p450 PF00067.22 EGC31512.1 - 1.4e-100 337.3 0.1 1.7e-100 337.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-TRAF PF02176.18 EGC31513.1 - 6.1e-17 62.1 16.9 2.5e-12 47.3 6.0 4.4 2 1 2 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC31513.1 - 2e-06 27.6 11.6 2e-06 27.6 11.6 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC31513.1 - 4.3e-05 23.6 15.9 0.00033 20.7 1.3 3.8 2 1 2 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC31513.1 - 6.7e-05 22.6 13.9 6.7e-05 22.6 13.9 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC31513.1 - 0.024 15.1 7.4 0.024 15.1 7.4 3.9 1 1 2 3 3 3 0 TRAF-like zinc-finger DUF3450 PF11932.8 EGC31513.1 - 0.027 13.8 0.5 0.043 13.1 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) zf-RING_2 PF13639.6 EGC31513.1 - 0.031 14.6 12.4 0.031 14.6 12.4 4.4 4 1 0 4 4 4 0 Ring finger domain RCC1_2 PF13540.6 EGC31514.1 - 3.1e-28 96.9 12.3 5.6e-11 41.9 1.8 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGC31514.1 - 4.6e-19 68.8 1.2 0.00027 21.5 0.0 7.1 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGC31514.1 - 8.7e-08 32.4 8.1 8.3e-07 29.2 0.1 4.2 4 0 0 4 4 4 1 BTB/POZ domain GRASP55_65 PF04495.14 EGC31515.1 - 3.9e-66 221.6 0.0 1.4e-47 161.5 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.6 EGC31515.1 - 2.6e-05 24.4 0.0 0.0024 18.2 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Phage_tail_NK PF16532.5 EGC31515.1 - 0.048 13.3 0.0 0.09 12.4 0.0 1.3 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales DUF2536 PF10750.9 EGC31518.1 - 0.018 15.0 1.8 0.018 15.0 1.8 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF2868 PF11067.8 EGC31518.1 - 0.2 11.1 0.7 0.21 11.0 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2868) ALMT PF11744.8 EGC31519.1 - 3.4 6.4 9.6 4 6.2 9.6 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter BUD22 PF09073.10 EGC31519.1 - 4.2 6.6 23.9 5.9 6.1 23.9 1.3 1 0 0 1 1 1 0 BUD22 SPX PF03105.19 EGC31519.1 - 4.9 7.0 28.2 6 6.7 28.2 1.1 1 0 0 1 1 1 0 SPX domain Brr6_like_C_C PF10104.9 EGC31522.1 - 6e-11 42.2 19.4 1.8e-10 40.7 0.5 3.4 2 1 1 3 3 3 2 Di-sulfide bridge nucleocytoplasmic transport domain DUF898 PF05987.13 EGC31522.1 - 0.0069 15.5 4.8 0.0074 15.4 0.7 2.0 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) 7TM_GPCR_Srw PF10324.9 EGC31522.1 - 0.013 14.8 18.1 0.095 12.0 8.5 2.7 2 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw DUF2207 PF09972.9 EGC31522.1 - 0.023 13.5 2.5 0.019 13.8 1.2 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) 7tm_1 PF00001.21 EGC31522.1 - 0.18 11.1 6.6 1.1 8.5 6.6 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.8 EGC31522.1 - 0.49 10.6 7.9 0.16 12.2 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) TMEM154 PF15102.6 EGC31522.1 - 3.1 7.7 9.6 0.21 11.5 2.6 2.2 1 1 1 2 2 2 0 TMEM154 protein family DUF2057 PF09829.9 EGC31524.1 - 0.0024 18.1 0.0 6.2 6.9 0.0 3.2 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2057) Med20 PF08612.11 EGC31524.1 - 0.025 14.0 0.3 0.7 9.2 0.1 2.6 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2458 PF10454.9 EGC31524.1 - 0.027 14.1 0.8 3.5 7.3 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) YwpF PF14183.6 EGC31524.1 - 0.17 11.9 0.5 27 4.8 0.0 2.5 2 0 0 2 2 2 0 YwpF-like protein C2 PF00168.30 EGC31526.1 - 0.00034 20.9 0.0 0.00047 20.4 0.0 1.3 1 0 0 1 1 1 1 C2 domain Copine PF07002.16 EGC31526.1 - 0.055 12.9 0.0 0.11 11.9 0.0 1.5 2 0 0 2 2 2 0 Copine DNase_II PF03265.15 EGC31528.1 - 9.3e-32 110.6 17.3 8.5e-26 91.0 9.9 2.2 1 1 0 2 2 2 2 Deoxyribonuclease II Usp PF00582.26 EGC31531.1 - 7.5e-19 68.6 0.0 1e-18 68.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family XisH PF08814.10 EGC31531.1 - 0.082 13.1 0.1 0.1 12.7 0.1 1.2 1 0 0 1 1 1 0 XisH protein HyaE PF07449.11 EGC31531.1 - 0.099 12.6 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PAP2 PF01569.21 EGC31532.1 - 6.7e-19 68.0 3.8 6.7e-19 68.0 3.8 1.9 2 1 0 2 2 2 1 PAP2 superfamily DUF212 PF02681.14 EGC31532.1 - 0.0018 18.4 0.8 0.092 12.9 0.1 2.3 1 1 1 2 2 2 1 Divergent PAP2 family PAP2_3 PF14378.6 EGC31532.1 - 0.47 10.1 6.0 0.53 9.9 2.7 2.5 1 1 1 2 2 2 0 PAP2 superfamily DUF4131 PF13567.6 EGC31532.1 - 1.6 8.3 7.4 7.7 6.1 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) CUE PF02845.16 EGC31533.1 - 1.2e-13 50.5 0.1 4.3e-13 48.7 0.1 2.1 1 0 0 1 1 1 1 CUE domain UPF0697 PF15117.6 EGC31533.1 - 1.4 9.0 8.1 4.1 7.5 8.1 1.8 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 SUIM_assoc PF16619.5 EGC31533.1 - 2.8 8.1 27.6 9.1 6.4 27.6 1.9 1 1 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 Glyco_transf_24 PF18404.1 EGC31534.1 - 8.7e-147 487.7 5.0 2.4e-146 486.2 5.0 1.8 1 0 0 1 1 1 1 Glucosyltransferase 24 Thioredoxin_14 PF18402.1 EGC31534.1 - 5.2e-50 170.8 3.7 5.2e-50 170.8 3.7 3.4 3 0 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_12 PF18400.1 EGC31534.1 - 5.8e-35 120.9 0.7 1.3e-34 119.7 0.7 1.7 1 0 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_13 PF18401.1 EGC31534.1 - 7.4e-30 103.6 1.7 7.4e-30 103.6 1.7 3.3 4 0 0 4 4 4 1 Thioredoxin-like domain UDP-g_GGTase PF06427.11 EGC31534.1 - 8.8e-27 93.4 0.0 2.4e-26 92.0 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Thioredoxin_15 PF18403.1 EGC31534.1 - 6.9e-08 32.7 5.5 6.9e-08 32.7 5.5 3.9 3 1 0 3 3 3 1 Thioredoxin-like domain Glyco_transf_8 PF01501.20 EGC31534.1 - 8.6e-06 25.5 0.3 8.6e-06 25.5 0.3 2.6 2 0 0 2 2 2 1 Glycosyl transferase family 8 WG_beta_rep PF14903.6 EGC31534.1 - 0.0051 17.1 0.7 0.016 15.5 0.1 2.3 2 0 0 2 2 2 1 WG containing repeat ubiquitin PF00240.23 EGC31534.1 - 0.0067 16.1 1.4 2.1 8.1 0.2 3.0 2 0 0 2 2 2 2 Ubiquitin family Bap31_Bap29_C PF18035.1 EGC31534.1 - 2.3 8.3 5.5 17 5.5 0.1 3.6 3 0 0 3 3 3 0 Bap31/Bap29 cytoplasmic coiled-coil domain PAC2 PF09754.9 EGC31535.1 - 4.1e-17 62.9 0.0 4.6e-17 62.7 0.0 1.2 1 0 0 1 1 1 1 PAC2 family ATP-grasp_2 PF08442.10 EGC31536.1 - 1.8e-74 249.7 2.7 2.9e-74 249.0 2.7 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.19 EGC31536.1 - 4.7e-27 94.7 1.7 9.9e-27 93.6 1.7 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.6 EGC31536.1 - 3.5e-13 49.5 0.3 5.4e-13 48.9 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.19 EGC31536.1 - 7.3e-05 22.6 1.7 0.0003 20.6 1.8 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp PF02222.22 EGC31536.1 - 0.035 13.7 0.2 0.092 12.3 0.1 1.7 2 0 0 2 2 2 0 ATP-grasp domain LUD_dom PF02589.15 EGC31536.1 - 0.057 13.1 0.0 0.16 11.6 0.0 1.7 1 1 0 1 1 1 0 LUD domain CENP-O PF09496.10 EGC31537.1 - 0.00092 19.3 0.4 0.00092 19.3 0.4 1.9 2 1 0 2 2 2 1 Cenp-O kinetochore centromere component DUF2931 PF11153.8 EGC31537.1 - 0.033 13.9 0.6 0.033 13.9 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2931) Alpha-amylase_C PF02806.18 EGC31539.1 - 1.8e-23 82.8 0.3 7.6e-23 80.8 0.1 2.2 3 0 0 3 3 3 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.24 EGC31539.1 - 1.4e-15 57.7 0.0 2.7e-13 50.2 0.1 2.4 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.18 EGC31539.1 - 2.2e-15 56.8 0.3 5.1e-15 55.6 0.3 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.6 EGC31539.1 - 0.024 13.7 0.1 0.048 12.8 0.1 1.4 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain AMPK1_CBM PF16561.5 EGC31539.1 - 0.028 14.6 0.7 0.088 13.0 0.1 2.1 2 0 0 2 2 2 0 Glycogen recognition site of AMP-activated protein kinase Atrophin-1 PF03154.15 EGC31540.1 - 0.0022 16.4 0.5 0.0022 16.4 0.5 2.0 2 0 0 2 2 2 1 Atrophin-1 family Mucin PF01456.17 EGC31540.1 - 0.25 11.3 24.2 0.44 10.5 24.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein CCDC53 PF10152.9 EGC31540.1 - 1.6 9.2 7.5 21 5.5 7.5 2.3 1 1 0 1 1 1 0 Subunit CCDC53 of WASH complex DUF3447 PF11929.8 EGC31540.1 - 4.2 7.4 10.9 6.5 6.8 0.8 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3447) LEA_1 PF03760.15 EGC31541.1 - 0.09 13.4 1.2 1.2 9.8 0.2 2.8 2 0 0 2 2 2 0 Late embryogenesis abundant (LEA) group 1 CN_hydrolase PF00795.22 EGC31542.1 - 7.5e-51 173.0 0.0 1e-50 172.5 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF3310 PF11753.8 EGC31543.1 - 0.062 13.5 0.2 0.13 12.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) Wzy_C_2 PF11846.8 EGC31543.1 - 3 7.7 5.6 0.76 9.7 0.3 2.3 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal Wzy_C PF04932.15 EGC31543.1 - 7.1 6.3 15.8 0.056 13.1 1.6 2.6 2 2 0 2 2 2 0 O-Antigen ligase HATPase_c PF02518.26 EGC31544.1 - 5.2e-28 97.8 0.1 1.1e-27 96.7 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC31544.1 - 3.4e-21 75.5 2.2 1.1e-19 70.7 0.3 2.7 3 0 0 3 3 3 1 Response regulator receiver domain HisKA PF00512.25 EGC31544.1 - 1.5e-17 63.4 0.0 4e-17 62.0 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.7 EGC31544.1 - 3.2e-11 43.4 0.0 3.3e-08 33.7 0.0 3.2 2 0 0 2 2 2 2 PAS domain PAS_3 PF08447.12 EGC31544.1 - 0.0069 16.7 0.0 0.081 13.2 0.0 2.3 2 0 0 2 2 2 1 PAS fold PG_binding_1 PF01471.18 EGC31545.1 - 1.4e-06 28.4 0.1 0.00038 20.6 0.0 3.6 3 0 0 3 3 3 2 Putative peptidoglycan binding domain PQ-loop PF04193.14 EGC31547.1 - 4.6e-17 61.5 26.0 3.2e-09 36.4 4.3 4.3 3 2 1 4 4 4 2 PQ loop repeat DUF4231 PF14015.6 EGC31547.1 - 0.25 11.8 3.6 0.19 12.2 1.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4231) CLN5 PF15014.6 EGC31548.1 - 1.1e-34 120.4 9.5 3.6e-34 118.8 9.5 1.6 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 FNIP PF05725.12 EGC31549.1 - 5.6e-06 26.4 38.3 0.00011 22.2 0.3 8.5 7 2 3 10 10 10 5 FNIP Repeat Rep_fac_C PF08542.11 EGC31549.1 - 0.098 13.1 0.1 0.75 10.2 0.0 2.6 2 0 0 2 2 2 0 Replication factor C C-terminal domain Secretin_N_2 PF07655.13 EGC31549.1 - 0.18 12.4 9.1 0.54 10.8 9.1 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Ank_4 PF13637.6 EGC31549.1 - 0.2 12.3 0.9 1.9 9.2 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) TSNAXIP1_N PF15739.5 EGC31549.1 - 2.1 8.7 10.1 0.14 12.6 0.6 3.9 4 0 0 4 4 4 0 Translin-associated factor X-interacting N-terminus Methyltransf_21 PF05050.12 EGC31550.1 - 0.011 15.8 0.1 0.031 14.3 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase FkbM domain TMEM154 PF15102.6 EGC31550.1 - 0.015 15.2 0.2 0.015 15.2 0.2 2.9 3 0 0 3 3 3 0 TMEM154 protein family SPX PF03105.19 EGC31550.1 - 0.034 14.1 5.7 0.053 13.4 5.7 1.3 1 0 0 1 1 1 0 SPX domain ETRAMP PF09716.10 EGC31550.1 - 0.18 11.9 4.4 0.11 12.6 1.0 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Macoilin PF09726.9 EGC31550.1 - 7.1 5.1 14.6 12 4.3 14.6 1.3 1 0 0 1 1 1 0 Macoilin family O_anti_polymase PF01901.16 EGC31551.1 - 0.073 12.3 2.4 0.087 12.1 2.4 1.2 1 0 0 1 1 1 0 Putative O-antigen polymerase OATP PF03137.20 EGC31551.1 - 0.077 11.3 0.5 0.097 10.9 0.5 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EIIBC-GUT_N PF03612.14 EGC31551.1 - 0.13 12.0 3.1 0.14 11.9 2.6 1.5 1 1 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF768 PF05589.11 EGC31551.1 - 0.21 11.6 2.9 4.7 7.3 0.7 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF768) MID_MedPIWI PF18296.1 EGC31551.1 - 0.32 10.7 9.6 0.49 10.1 9.5 1.3 1 1 0 1 1 1 0 MID domain of medPIWI Secretin_N_2 PF07655.13 EGC31551.1 - 1.2 9.8 31.2 0.066 13.8 20.0 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain CFIA_Pcf11 PF11526.8 EGC31551.1 - 1.5 9.4 24.8 1.2 9.7 12.4 2.2 2 0 0 2 2 2 0 Subunit of cleavage factor IA Pcf11 Peroxin-13_N PF04088.13 EGC31551.1 - 2.3 8.5 6.8 2 8.7 4.9 1.8 1 1 1 2 2 2 0 Peroxin 13, N-terminal region COG4 PF08318.12 EGC31551.1 - 2.6 7.0 9.8 1.5 7.8 7.4 1.7 1 1 1 2 2 2 0 COG4 transport protein ETRAMP PF09716.10 EGC31551.1 - 2.8 8.1 23.9 0.025 14.7 12.6 2.3 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PH_4 PF15404.6 EGC31551.1 - 6.7 6.5 10.0 0.85 9.4 3.9 2.0 2 0 0 2 2 2 0 Pleckstrin homology domain Orf78 PF06024.12 EGC31551.1 - 8.7 6.7 25.9 0.043 14.1 12.6 2.2 1 1 1 2 2 2 0 Orf78 (ac78) TRAP_beta PF05753.14 EGC31552.1 - 6.7e-47 159.2 1.6 8e-47 158.9 1.6 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.11 EGC31552.1 - 0.029 14.6 0.0 0.054 13.8 0.0 1.4 1 1 0 1 1 1 0 CARDB MPLKIP PF15502.6 EGC31553.1 - 7e-06 26.2 1.8 7e-06 26.2 1.8 3.9 4 2 0 4 4 4 1 M-phase-specific PLK1-interacting protein RGS PF00615.19 EGC31554.1 - 1.1e-49 167.6 31.3 1.9e-20 73.3 2.0 4.8 5 0 0 5 5 5 3 Regulator of G protein signaling domain RGS-like PF09128.11 EGC31554.1 - 6.4e-07 29.3 7.6 0.0028 17.4 0.1 3.5 3 0 0 3 3 3 2 Regulator of G protein signalling-like domain EF1G PF00647.19 EGC31554.1 - 0.071 13.2 4.1 1.8 8.7 0.1 3.8 3 0 0 3 3 3 0 Elongation factor 1 gamma, conserved domain MAP70 PF07058.11 EGC31554.1 - 8.8 4.9 8.8 21 3.7 8.8 1.6 1 0 0 1 1 1 0 Microtubule-associated protein 70 RNA_pol_Rpb4 PF03874.16 EGC31555.1 - 0.6 10.5 7.9 0.15 12.4 0.4 3.3 3 0 0 3 3 3 0 RNA polymerase Rpb4 bZIP_1 PF00170.21 EGC31556.1 - 2.3e-08 34.0 11.3 2.3e-08 34.0 11.3 2.2 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC31556.1 - 1.1e-06 28.7 9.9 1.1e-06 28.7 9.9 2.7 3 0 0 3 3 3 1 Basic region leucine zipper KASH_CCD PF14662.6 EGC31556.1 - 0.003 17.4 15.8 0.0054 16.6 15.8 1.3 1 0 0 1 1 1 1 Coiled-coil region of CCDC155 or KASH DUF1672 PF07901.11 EGC31556.1 - 0.03 13.7 2.8 0.057 12.7 2.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1672) RNase_HII PF01351.18 EGC31557.1 - 3.1e-43 147.9 0.0 3.4e-43 147.8 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII NleF_casp_inhib PF16809.5 EGC31557.1 - 0.059 13.3 3.3 0.13 12.1 2.4 1.8 2 0 0 2 2 2 0 NleF caspase inhibitor CBM49 PF09478.10 EGC31558.1 - 2.1e-15 56.8 4.8 5.2e-15 55.5 4.8 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Glyco_hydro_9 PF00759.19 EGC31560.1 - 9.9e-125 417.2 16.0 1.1e-124 417.0 16.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FNIP PF05725.12 EGC31561.1 - 1.2e-29 102.2 50.9 2.6e-13 49.9 5.9 6.4 2 2 4 7 7 7 6 FNIP Repeat Flu_NS1 PF00600.19 EGC31562.1 - 0.081 12.5 0.2 0.14 11.7 0.2 1.3 1 0 0 1 1 1 0 Influenza non-structural protein (NS1) adh_short PF00106.25 EGC31563.1 - 1.6e-07 31.0 0.0 3.4e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC31563.1 - 0.0016 18.0 0.0 0.0027 17.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC31563.1 - 0.0026 17.7 0.0 0.0048 16.8 0.0 1.3 1 0 0 1 1 1 1 KR domain PIN_11 PF18479.1 EGC31563.1 - 0.0062 16.7 1.2 0.027 14.7 1.2 2.2 1 0 0 1 1 1 1 PIN like domain EF-hand_13 PF17958.1 EGC31563.1 - 0.062 13.1 0.2 0.3 10.9 0.2 2.2 1 0 0 1 1 1 0 EF-hand domain PriC PF07445.12 EGC31563.1 - 5.3 6.9 8.9 1.7 8.5 4.5 2.4 2 0 0 2 2 2 0 Primosomal replication protein priC CLN3 PF02487.17 EGC31564.1 - 0.00047 19.3 2.9 0.00047 19.3 2.9 2.2 2 0 0 2 2 2 1 CLN3 protein Dimer_Tnp_hAT PF05699.14 EGC31565.1 - 2.4e-12 46.5 0.1 5.7e-12 45.3 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nup54_57_C PF18570.1 EGC31566.1 - 0.041 13.5 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 NUP57/Nup54 C-terminal domain RIC3 PF15361.6 EGC31567.1 - 0.005 17.2 0.4 0.01 16.3 0.4 1.5 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 TMEM154 PF15102.6 EGC31568.1 - 0.0016 18.4 0.5 0.0029 17.5 0.5 1.3 1 0 0 1 1 1 1 TMEM154 protein family DIL PF01843.19 EGC31569.1 - 4.6e-23 81.5 2.1 4.6e-23 81.5 2.1 4.0 4 1 0 4 4 4 1 DIL domain THOC7 PF05615.13 EGC31569.1 - 0.011 16.0 8.8 0.011 16.0 8.8 10.5 2 1 6 8 8 8 0 Tho complex subunit 7 TMF_TATA_bd PF12325.8 EGC31569.1 - 0.012 15.9 1.6 0.012 15.9 1.6 11.6 2 1 8 11 11 11 0 TATA element modulatory factor 1 TATA binding PRKG1_interact PF15898.5 EGC31569.1 - 0.015 16.2 5.5 0.015 16.2 5.5 11.4 2 1 5 8 8 8 0 cGMP-dependent protein kinase interacting domain Spc7 PF08317.11 EGC31569.1 - 0.14 11.0 194.4 0.011 14.6 29.0 8.5 1 1 8 9 9 9 0 Spc7 kinetochore protein Fez1 PF06818.15 EGC31569.1 - 1.9 8.9 173.6 0.35 11.3 32.9 7.3 2 1 5 7 7 7 0 Fez1 EspB_PE PF18625.1 EGC31569.1 - 2.6 8.6 9.2 1.7 9.2 0.4 4.3 3 0 0 3 3 3 0 ESX-1 secreted protein B PE domain DUF3439 PF11921.8 EGC31569.1 - 7 6.6 5.8 5.9 6.9 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PRKCSH-like PF12999.7 EGC31570.1 - 3.7e-46 157.1 11.7 3.7e-46 157.1 11.7 2.4 2 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.6 EGC31570.1 - 1.8e-29 102.4 0.5 1.8e-29 102.4 0.5 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein PRKCSH PF07915.13 EGC31570.1 - 8.8e-05 23.4 1.6 8.8e-05 23.4 1.6 3.6 3 2 0 3 3 3 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.18 EGC31570.1 - 0.019 15.1 17.7 0.31 11.3 9.5 2.8 2 0 0 2 2 2 0 Low-density lipoprotein receptor domain class A Sad1_UNC PF07738.13 EGC31570.1 - 0.046 13.7 0.5 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Sad1 / UNC-like C-terminal CCD48 PF15799.5 EGC31570.1 - 0.15 10.4 8.8 0.2 9.9 8.8 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 48 HIP1_clath_bdg PF16515.5 EGC31570.1 - 4.7 7.9 15.7 7.5 7.2 11.2 2.7 2 0 0 2 2 2 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BUD22 PF09073.10 EGC31570.1 - 6.2 6.0 30.2 9.8 5.4 30.2 1.3 1 0 0 1 1 1 0 BUD22 PH PF00169.29 EGC31571.1 - 5.3e-15 55.8 0.2 5.3e-15 55.8 0.2 2.2 2 1 0 2 2 2 1 PH domain SH3_1 PF00018.28 EGC31571.1 - 1.7e-12 46.8 3.1 5.3e-12 45.2 1.4 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGC31571.1 - 1.8e-10 40.5 2.0 5.5e-09 35.8 2.0 2.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC31571.1 - 1e-05 25.1 0.5 4.3e-05 23.1 0.5 2.2 1 1 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.6 EGC31571.1 - 2.2e-05 24.7 0.1 4.6e-05 23.6 0.1 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGC31571.1 - 0.017 15.5 0.4 0.017 15.5 0.4 4.0 2 2 1 3 3 3 0 Pleckstrin homology domain Tail_tube PF10618.9 EGC31571.1 - 0.023 14.6 0.1 0.41 10.5 0.0 2.3 2 0 0 2 2 2 0 Phage tail tube protein SH3_3 PF08239.11 EGC31571.1 - 0.12 12.7 0.3 0.32 11.3 0.3 1.7 1 0 0 1 1 1 0 Bacterial SH3 domain PH_9 PF15410.6 EGC31571.1 - 0.14 12.6 3.2 0.42 11.0 1.6 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain ATG7_N PF16420.5 EGC31572.1 - 4.4e-82 276.1 0.4 7.4e-82 275.4 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-like modifier-activating enzyme ATG7 N-terminus ThiF PF00899.21 EGC31572.1 - 1.4e-43 149.0 0.0 2.2e-43 148.4 0.0 1.3 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 EGC31572.1 - 0.0033 16.8 0.0 0.7 9.2 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGC31572.1 - 0.01 15.9 0.0 0.62 10.1 0.0 2.5 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGC31572.1 - 0.062 13.8 0.0 0.22 12.0 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding ELFV_dehydrog PF00208.21 EGC31572.1 - 0.12 12.1 0.0 0.3 10.8 0.0 1.6 2 0 0 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CAML PF14963.6 EGC31575.1 - 4.2 7.4 6.5 5.2 7.1 6.5 1.1 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand UQ_con PF00179.26 EGC31576.1 - 3.5e-38 130.4 0.0 7e-38 129.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGC31576.1 - 0.0035 17.2 0.0 0.0065 16.3 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.22 EGC31576.1 - 0.019 15.2 0.1 0.037 14.3 0.1 1.5 1 0 0 1 1 1 0 RWD domain Bot1p PF12298.8 EGC31576.1 - 0.069 13.3 4.2 0.1 12.8 4.2 1.3 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein DUF4692 PF15763.5 EGC31576.1 - 0.1 13.1 3.0 0.14 12.6 3.0 1.1 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Pro-kuma_activ PF09286.11 EGC31577.1 - 1.8e-32 112.6 0.7 3.2e-32 111.8 0.7 1.5 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC31577.1 - 0.00017 21.0 3.8 0.0012 18.2 3.8 2.2 1 1 0 1 1 1 1 Subtilase family EPL1 PF10513.9 EGC31578.1 - 3.1 8.2 29.4 3.9 7.8 6.0 3.7 3 0 0 3 3 3 0 Enhancer of polycomb-like DUF775 PF05603.12 EGC31579.1 - 7.5e-48 162.7 4.8 9.7e-48 162.3 4.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) ThrE PF06738.12 EGC31580.1 - 2.6e-59 200.5 20.9 3e-52 177.4 4.0 2.4 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGC31580.1 - 1.3e-17 64.1 31.5 6.4e-13 49.0 10.3 2.3 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE TruB_C_2 PF16198.5 EGC31580.1 - 0.2 11.9 0.0 0.6 10.3 0.0 1.8 1 0 0 1 1 1 0 tRNA pseudouridylate synthase B C-terminal domain DASH_Dam1 PF08653.10 EGC31580.1 - 0.4 10.5 5.2 2 8.3 2.9 2.9 2 0 0 2 2 2 0 DASH complex subunit Dam1 EPO_TPO PF00758.18 EGC31580.1 - 0.42 10.6 6.1 2.8 8.0 1.9 2.9 3 0 0 3 3 3 0 Erythropoietin/thrombopoietin ubiquitin PF00240.23 EGC31581.1 - 4.7e-15 55.1 1.2 1.9e-14 53.2 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EGC31581.1 - 0.00051 19.8 0.3 0.001 18.8 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGC31581.1 - 0.032 14.2 0.6 0.32 11.0 0.1 2.4 2 1 0 2 2 2 0 TANK binding kinase 1 ubiquitin-like domain Sec15 PF04091.12 EGC31582.1 - 1.9e-54 185.2 17.2 1.9e-54 185.2 17.2 2.5 2 1 0 2 2 2 1 Exocyst complex subunit Sec15-like CTD_bind PF04818.13 EGC31583.1 - 0.00011 23.0 0.1 0.00011 23.0 0.1 2.8 3 0 0 3 3 3 1 RNA polymerase II-binding domain. FAD_binding_8 PF08022.12 EGC31583.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 FAD-binding domain DnaB_2 PF07261.11 EGC31583.1 - 2.2 8.1 8.2 3.2 7.6 0.0 4.2 5 0 0 5 5 5 0 Replication initiation and membrane attachment CTK3 PF12243.8 EGC31584.1 - 0.0011 18.9 0.1 0.0012 18.8 0.1 1.1 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 ELMO_CED12 PF04727.13 EGC31584.1 - 0.087 12.9 0.1 0.092 12.8 0.1 1.1 1 0 0 1 1 1 0 ELMO/CED-12 family Nbs1_C PF08599.10 EGC31587.1 - 0.14 12.3 0.4 0.36 11.0 0.4 1.6 1 0 0 1 1 1 0 DNA damage repair protein Nbs1 HEAT PF02985.22 EGC31587.1 - 0.49 10.8 1.7 73 4.0 0.1 3.7 3 0 0 3 3 3 0 HEAT repeat RsfS PF02410.15 EGC31589.1 - 2.9e-20 72.6 0.3 8.9e-20 71.0 0.3 1.9 1 0 0 1 1 1 1 Ribosomal silencing factor during starvation DUF3391 PF11871.8 EGC31589.1 - 2.8 8.5 13.7 1.5 9.4 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3391) zf-RING_2 PF13639.6 EGC31590.1 - 2.3e-13 50.2 9.9 3.1e-13 49.8 9.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC31590.1 - 1.8e-10 40.4 2.7 1.8e-10 40.4 2.7 1.6 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_5 PF14634.6 EGC31590.1 - 6.2e-08 32.5 8.8 8.8e-08 32.0 8.8 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC31590.1 - 5.9e-07 29.2 5.9 8.6e-07 28.7 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC31590.1 - 1.1e-06 28.6 6.5 4.3e-06 26.6 7.0 1.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC31590.1 - 1e-05 25.3 9.8 2.2e-05 24.2 9.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31590.1 - 1.2e-05 25.5 12.2 0.00011 22.4 12.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC31590.1 - 2.7e-05 23.9 6.9 5e-05 23.1 6.9 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGC31590.1 - 2.9e-05 23.8 9.8 4.4e-05 23.2 9.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGC31590.1 - 0.017 15.1 5.4 0.038 14.0 5.4 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EGC31590.1 - 0.027 14.6 4.9 0.073 13.2 4.9 1.7 1 1 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EGC31590.1 - 0.036 13.7 8.2 0.088 12.4 8.3 1.7 1 1 0 1 1 1 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGC31590.1 - 0.22 11.7 8.9 3 8.1 8.9 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain DUF3986 PF13143.6 EGC31591.1 - 0.0085 17.1 0.8 0.024 15.6 0.8 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3986) Titin_Ig-rpts PF06582.12 EGC31591.1 - 0.035 14.0 0.1 0.069 13.1 0.1 1.5 1 0 0 1 1 1 0 Titin repeat ZapA PF05164.13 EGC31591.1 - 0.14 12.6 0.8 20 5.7 0.3 2.5 2 0 0 2 2 2 0 Cell division protein ZapA CASP_C PF08172.12 EGC31592.1 - 2.2e-57 194.3 1.3 2.6e-57 194.0 1.3 1.0 1 0 0 1 1 1 1 CASP C terminal Golgin_A5 PF09787.9 EGC31592.1 - 0.00015 21.3 0.4 0.049 13.1 0.0 2.1 2 0 0 2 2 2 2 Golgin subfamily A member 5 DUF4164 PF13747.6 EGC31592.1 - 0.017 15.4 0.4 0.028 14.7 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) KLRAQ PF10205.9 EGC31592.1 - 0.019 15.2 0.3 0.035 14.3 0.3 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein CENP-H PF05837.12 EGC31592.1 - 0.044 14.2 0.1 0.07 13.5 0.1 1.3 1 0 0 1 1 1 0 Centromere protein H (CENP-H) DUF5366 PF17328.2 EGC31592.1 - 0.049 13.7 0.4 0.073 13.2 0.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5366) Acetyltransf_10 PF13673.7 EGC31593.1 - 8.3e-06 25.8 0.0 1.3e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC31593.1 - 0.00018 21.8 0.0 0.00028 21.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC31593.1 - 0.0015 18.9 0.1 0.0031 17.9 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC31593.1 - 0.022 14.7 0.0 0.044 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Sec20 PF03908.13 EGC31594.1 - 3.7e-06 26.8 0.3 3.7e-06 26.8 0.3 2.4 2 1 1 3 3 3 1 Sec20 V-SNARE_C PF12352.8 EGC31594.1 - 1e-05 25.7 0.7 2.4e-05 24.5 0.5 1.8 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.15 EGC31594.1 - 0.0033 17.8 3.7 0.0037 17.6 1.8 2.1 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus MPS2 PF17060.5 EGC31594.1 - 0.011 15.1 5.5 0.016 14.5 5.5 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 SIT PF15330.6 EGC31594.1 - 0.017 15.6 0.0 0.017 15.6 0.0 2.3 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT DUF812 PF05667.11 EGC31594.1 - 0.04 12.8 6.7 0.13 11.2 6.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF812) OppC_N PF12911.7 EGC31594.1 - 0.05 13.6 0.1 0.098 12.6 0.1 1.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Orai-1 PF07856.12 EGC31594.1 - 0.066 12.9 0.2 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Mediator of CRAC channel activity EphA2_TM PF14575.6 EGC31594.1 - 0.12 13.3 0.1 0.67 10.9 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Laminin_II PF06009.12 EGC31594.1 - 0.12 12.4 5.1 4.6 7.3 0.2 2.2 2 0 0 2 2 2 0 Laminin Domain II Ctr PF04145.15 EGC31594.1 - 0.18 12.4 0.5 1.2 9.7 0.0 2.1 2 0 0 2 2 2 0 Ctr copper transporter family ALMT PF11744.8 EGC31594.1 - 0.28 10.0 3.7 0.43 9.4 3.7 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 EGC31594.1 - 0.72 8.7 7.8 1.1 8.1 7.8 1.2 1 1 0 1 1 1 0 LMBR1-like membrane protein DUF4472 PF14739.6 EGC31594.1 - 0.75 10.6 6.9 0.27 12.0 2.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) DUF4834 PF16118.5 EGC31594.1 - 0.79 10.7 5.0 1.7 9.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) DUF3328 PF11807.8 EGC31594.1 - 0.81 9.4 3.8 0.29 10.9 1.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) WXG100 PF06013.12 EGC31594.1 - 1.3 9.3 6.1 0.63 10.3 0.5 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG APG6_N PF17675.1 EGC31594.1 - 3.6 8.1 9.9 8.4 6.9 3.3 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region MFS_1 PF07690.16 EGC31595.1 - 1.4e-39 136.0 28.8 6.3e-34 117.4 11.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC31595.1 - 2.1e-16 59.9 25.6 2.1e-15 56.5 25.7 2.1 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_4 PF06779.14 EGC31595.1 - 0.00026 20.4 11.1 0.011 15.0 1.4 3.2 2 1 1 3 3 3 3 Uncharacterised MFS-type transporter YbfB ECSCR PF15820.5 EGC31595.1 - 0.4 10.5 0.0 0.4 10.5 0.0 2.9 4 1 0 4 4 4 0 Endothelial cell-specific chemotaxis regulator TIM21 PF08294.11 EGC31595.1 - 9.5 6.1 8.7 30 4.5 0.1 4.0 5 0 0 5 5 5 0 TIM21 DUF1394 PF07159.12 EGC31596.1 - 5.9e-127 423.1 0.3 6.7e-127 422.9 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) DUF4835 PF16119.5 EGC31596.1 - 0.28 10.3 2.4 7.5 5.6 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4835) DIL PF01843.19 EGC31597.1 - 1.6e-16 60.5 0.4 2.7e-16 59.7 0.4 1.3 1 0 0 1 1 1 1 DIL domain ketoacyl-synt PF00109.26 EGC31599.1 - 9.5e-69 231.8 0.0 1.6e-68 231.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC31599.1 - 2.9e-46 158.5 0.0 6.5e-46 157.3 0.0 1.6 2 0 0 2 2 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGC31599.1 - 3.4e-44 150.9 0.0 5.9e-44 150.2 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC31599.1 - 3.7e-31 107.6 0.0 1.1e-30 106.1 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC31599.1 - 4.8e-22 78.7 0.0 7.8e-17 61.8 0.0 3.4 3 0 0 3 3 3 2 KR domain KAsynt_C_assoc PF16197.5 EGC31599.1 - 1e-16 61.4 2.1 1.3e-15 57.8 0.2 3.1 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC31599.1 - 2.2e-12 46.8 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC31599.1 - 2.4e-11 44.8 0.0 1.1e-10 42.7 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC31599.1 - 2.7e-08 33.6 0.2 8.3e-08 32.0 0.2 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Methyltransf_12 PF08242.12 EGC31599.1 - 2.5e-07 31.4 0.0 1.9e-06 28.5 0.0 2.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EGC31599.1 - 3.2e-07 30.2 0.3 9.5e-07 28.7 0.1 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC31599.1 - 6.4e-07 29.6 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.26 EGC31599.1 - 6.9e-06 26.1 0.0 3.9e-05 23.6 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase adh_short PF00106.25 EGC31599.1 - 8.4e-05 22.1 0.0 0.16 11.4 0.0 3.4 3 0 0 3 3 3 1 short chain dehydrogenase 3Beta_HSD PF01073.19 EGC31599.1 - 0.0003 19.9 0.3 0.00071 18.7 0.3 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Thiolase_N PF00108.23 EGC31599.1 - 0.00088 18.7 0.1 0.0023 17.3 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EGC31599.1 - 0.0037 16.7 0.2 0.0087 15.5 0.2 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC31599.1 - 0.042 13.0 0.0 0.12 11.5 0.0 1.8 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGC31599.1 - 0.048 13.5 0.0 0.8 9.6 0.0 2.7 2 1 0 2 2 2 0 NAD(P)H-binding PIP5K PF01504.18 EGC31600.1 - 1.8e-70 237.3 9.3 3.5e-70 236.3 9.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Homeobox_KN PF05920.11 EGC31601.1 - 1.8e-17 62.9 1.3 2.9e-17 62.3 1.3 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGC31601.1 - 1.4e-08 34.5 0.3 2.1e-08 33.9 0.3 1.3 1 0 0 1 1 1 1 Homeodomain Secretin_N_2 PF07655.13 EGC31601.1 - 1.5 9.4 16.4 2.6 8.6 16.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 EGC31601.1 - 9.2 4.5 7.5 9.3 4.5 7.5 1.1 1 0 0 1 1 1 0 Menin Rap_GAP PF02145.15 EGC31602.1 - 3.3e-57 193.0 0.5 3.3e-57 193.0 0.5 3.0 2 0 0 2 2 2 1 Rap/ran-GAP DUF3384 PF11864.8 EGC31602.1 - 4.4e-50 171.0 11.1 2.8e-44 151.8 10.1 6.4 6 2 1 7 7 7 2 Domain of unknown function (DUF3384) Tuberin PF03542.16 EGC31602.1 - 3e-11 43.1 8.7 3e-11 43.1 8.7 6.1 8 0 0 8 8 8 2 Tuberin Acetyltransf_1 PF00583.25 EGC31603.1 - 3e-08 33.9 0.0 3.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC31603.1 - 7.5e-08 32.4 0.0 8.7e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC31603.1 - 0.00078 19.8 0.0 0.001 19.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC31603.1 - 0.072 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase COG2 PF06148.11 EGC31604.1 - 5.7e-33 113.8 6.5 5.7e-33 113.8 6.5 3.1 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF3510 PF12022.8 EGC31604.1 - 1.2e-30 106.5 0.1 1.2e-30 106.5 0.1 4.2 4 1 0 4 4 4 1 Domain of unknown function (DUF3510) Vps51 PF08700.11 EGC31604.1 - 0.0074 16.3 0.6 0.0074 16.3 0.6 4.6 3 1 1 4 4 4 1 Vps51/Vps67 DUF2481 PF10654.9 EGC31604.1 - 0.052 13.5 0.1 0.052 13.5 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2481) EIN3 PF04873.13 EGC31604.1 - 0.15 11.3 0.1 0.15 11.3 0.1 2.3 3 0 0 3 3 3 0 Ethylene insensitive 3 Zn_ribbon_2 PF12674.7 EGC31604.1 - 0.86 10.3 0.0 0.86 10.3 0.0 2.7 3 0 0 3 3 3 0 Putative zinc ribbon domain RabGAP-TBC PF00566.18 EGC31605.1 - 3.9e-23 82.2 0.2 3.9e-23 82.2 0.2 2.8 2 1 0 2 2 2 1 Rab-GTPase-TBC domain SUa-2TM PF18179.1 EGC31606.1 - 0.066 12.5 2.7 0.095 12.0 2.7 1.2 1 0 0 1 1 1 0 SMODS- and Ubiquitin system-associated 2TM effector domain DUF2254 PF10011.9 EGC31606.1 - 0.46 9.2 5.4 0.62 8.8 5.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF2207 PF09972.9 EGC31606.1 - 0.47 9.1 4.0 0.62 8.8 4.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) WD40 PF00400.32 EGC31607.1 - 0.001 19.8 1.0 8.5 7.4 0.0 4.4 5 0 0 5 5 5 2 WD domain, G-beta repeat COQ7 PF03232.13 EGC31609.1 - 3e-71 238.7 0.1 3.6e-71 238.5 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.17 EGC31609.1 - 1.7e-05 25.2 0.3 3.6e-05 24.2 0.2 1.7 1 1 0 1 1 1 1 Rubrerythrin Ferritin_2 PF13668.6 EGC31609.1 - 0.02 15.1 0.6 0.24 11.6 0.1 2.2 1 1 1 2 2 2 0 Ferritin-like domain R_equi_Vir PF05526.11 EGC31610.1 - 0.074 12.9 0.2 0.13 12.1 0.2 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein Peptidase_U4 PF03419.13 EGC31611.1 - 0.0024 17.2 2.0 0.0035 16.7 2.0 1.2 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Wzy_C PF04932.15 EGC31611.1 - 0.003 17.2 1.1 0.0038 16.9 1.1 1.2 1 0 0 1 1 1 1 O-Antigen ligase Erf4 PF10256.9 EGC31611.1 - 0.0087 16.2 3.4 0.22 11.6 3.4 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4131 PF13567.6 EGC31611.1 - 0.022 14.4 0.2 0.031 13.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Integrase_H2C2 PF17921.1 EGC31612.1 - 2e-05 24.6 0.0 3.5e-05 23.8 0.0 1.3 1 0 0 1 1 1 1 Integrase zinc binding domain VWA_2 PF13519.6 EGC31613.1 - 0.00073 20.2 3.3 0.0029 18.2 0.2 3.5 2 1 0 2 2 2 1 von Willebrand factor type A domain Sec23_BS PF08033.12 EGC31613.1 - 0.0011 19.6 0.7 0.0049 17.6 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain VWA PF00092.28 EGC31613.1 - 0.0043 17.3 7.5 0.66 10.2 5.0 3.7 2 1 0 2 2 2 1 von Willebrand factor type A domain Sec23_trunk PF04811.15 EGC31613.1 - 0.0058 16.2 0.6 1.7 8.1 0.0 3.0 2 1 1 3 3 3 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EGC31613.1 - 0.0069 16.4 1.0 0.019 15.0 1.0 1.8 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger VWA_CoxE PF05762.14 EGC31613.1 - 0.069 12.5 0.1 2.4 7.5 0.0 2.6 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein DUF1179 PF06678.11 EGC31613.1 - 0.36 10.8 6.1 0.26 11.3 1.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1179) TFIIA PF03153.13 EGC31613.1 - 1.1 9.2 20.0 0.018 15.1 7.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit cobW PF02492.19 EGC31614.1 - 4.9e-08 32.8 0.6 0.017 14.7 0.0 3.1 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGC31614.1 - 6.1e-06 26.1 0.1 1.8e-05 24.6 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.6 EGC31614.1 - 0.0071 16.6 0.4 0.48 10.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC31614.1 - 0.076 13.4 0.0 2.2 8.7 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain VESA1_N PF12785.7 EGC31614.1 - 0.47 9.4 10.3 0.66 8.9 10.3 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 zf-RING_2 PF13639.6 EGC31615.1 - 1.4e-12 47.7 7.6 1.8e-12 47.4 7.6 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC31615.1 - 1.5e-11 43.9 7.2 2e-11 43.5 7.2 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC31615.1 - 7.3e-09 35.2 4.8 9.5e-09 34.9 2.5 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC31615.1 - 7.3e-08 32.6 10.7 8e-07 29.3 10.7 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC31615.1 - 3.8e-07 29.9 5.9 5.4e-07 29.4 5.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC31615.1 - 2.1e-05 24.3 3.1 3.2e-05 23.7 3.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC31615.1 - 2.8e-05 24.1 1.7 2.8e-05 24.1 1.7 1.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGC31615.1 - 3.8e-05 23.6 4.0 8.5e-05 22.5 4.0 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC31615.1 - 4.7e-05 23.3 3.5 6.6e-05 22.8 3.5 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC31615.1 - 7.9e-05 22.4 3.7 0.00015 21.6 3.7 1.4 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Prok-RING_1 PF14446.6 EGC31615.1 - 0.00036 20.4 7.5 0.013 15.5 2.6 2.2 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 Zn_ribbon_17 PF17120.5 EGC31615.1 - 0.0014 18.2 4.0 0.0021 17.6 4.0 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING-like PF08746.11 EGC31615.1 - 0.0034 17.7 3.4 0.0049 17.2 3.4 1.3 1 0 0 1 1 1 1 RING-like domain Vps39_2 PF10367.9 EGC31615.1 - 0.0045 17.4 0.9 0.033 14.6 0.1 1.9 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 zinc_ribbon_16 PF17034.5 EGC31615.1 - 0.073 13.3 4.4 0.1 12.8 4.4 1.3 1 1 0 1 1 1 0 Zinc-ribbon like family Rad50_zn_hook PF04423.14 EGC31615.1 - 0.089 12.6 2.4 0.12 12.2 0.1 2.1 2 1 0 2 2 2 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EGC31615.1 - 0.15 11.8 7.3 0.76 9.6 7.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain CTU2 PF10288.9 EGC31615.1 - 0.32 11.2 2.9 4.5 7.6 2.9 2.0 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 PHD PF00628.29 EGC31615.1 - 0.33 10.9 8.0 1.1 9.3 7.8 2.0 1 1 0 1 1 1 0 PHD-finger RINGv PF12906.7 EGC31615.1 - 0.35 11.0 6.1 1.2 9.3 6.1 1.8 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_4 PF15227.6 EGC31615.1 - 0.46 10.7 6.1 1.4 9.1 6.3 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-C3H2C3 PF17122.5 EGC31615.1 - 0.9 9.6 7.6 2.1 8.4 7.6 1.7 1 1 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EGC31615.1 - 1.1 9.5 7.0 11 6.3 7.0 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Gaa1 PF04114.14 EGC31617.1 - 2e-87 294.3 18.7 2.3e-81 274.3 2.1 2.3 2 0 0 2 2 2 2 Gaa1-like, GPI transamidase component DUF4834 PF16118.5 EGC31617.1 - 0.053 14.5 1.6 3.1 8.8 1.3 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Phage_Gp23 PF10669.9 EGC31617.1 - 0.11 12.8 0.0 0.37 11.1 0.0 1.9 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) Macoilin PF09726.9 EGC31618.1 - 0.46 9.0 12.8 0.56 8.7 12.8 1.2 1 0 0 1 1 1 0 Macoilin family SEEEED PF14797.6 EGC31618.1 - 3 8.0 31.1 3.4 7.8 25.0 2.1 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex Terminase_6C PF17289.2 EGC31619.1 - 0.11 12.6 1.0 0.56 10.3 0.9 2.1 2 0 0 2 2 2 0 Terminase RNaseH-like domain Med27 PF11571.8 EGC31619.1 - 0.3 11.5 2.3 0.79 10.1 0.1 2.8 2 0 0 2 2 2 0 Mediator complex subunit 27 ALMT PF11744.8 EGC31619.1 - 4.1 6.1 16.4 0.36 9.6 11.9 1.5 2 0 0 2 2 2 0 Aluminium activated malate transporter ADP_PFK_GK PF04587.15 EGC31620.1 - 1.8e-138 461.7 0.0 2.2e-138 461.4 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region ETRAMP PF09716.10 EGC31620.1 - 4.9 7.3 9.5 1.4 9.1 2.2 2.6 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FH2 PF02181.23 EGC31621.1 - 2.4e-82 277.0 9.6 3.2e-82 276.6 9.6 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain Epimerase PF01370.21 EGC31623.1 - 2e-10 40.5 0.0 3.9e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC31623.1 - 3.7e-10 39.3 0.0 4.5e-10 39.0 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGC31623.1 - 5.5e-08 32.3 0.0 1.7e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGC31623.1 - 0.0001 21.8 0.0 0.0076 15.7 0.0 2.8 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC31623.1 - 0.00031 20.7 0.0 0.00097 19.1 0.0 1.8 1 1 0 1 1 1 1 NAD(P)H-binding Polysacc_synt_2 PF02719.15 EGC31623.1 - 0.00079 18.6 0.0 0.0016 17.6 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein UPF0203 PF05254.12 EGC31624.1 - 9.2e-18 64.3 5.9 1e-17 64.1 5.9 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) CX9C PF16860.5 EGC31624.1 - 0.0041 17.1 4.5 0.013 15.5 0.2 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, Cmc1 PF08583.10 EGC31624.1 - 0.029 14.4 2.9 1.6 8.8 0.3 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX17 PF05051.13 EGC31624.1 - 0.03 14.7 1.6 0.064 13.6 1.6 1.5 1 1 0 1 1 1 0 Cytochrome C oxidase copper chaperone (COX17) RINGv PF12906.7 EGC31624.1 - 0.083 13.0 2.5 0.22 11.7 2.5 1.9 1 1 0 1 1 1 0 RING-variant domain Citrate_synt PF00285.21 EGC31625.1 - 2.8e-109 365.5 0.0 3.2e-109 365.3 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain DSS1_SEM1 PF05160.13 EGC31626.1 - 4.3e-14 52.3 21.1 4.3e-14 52.3 21.1 1.5 1 1 0 1 1 1 1 DSS1/SEM1 family YfhD PF14151.6 EGC31626.1 - 9.6 6.4 13.8 14 5.9 7.6 2.1 1 1 1 2 2 2 0 YfhD-like protein DUF5347 PF17282.2 EGC31627.1 - 2 8.8 9.5 2.6 8.4 5.3 3.0 2 0 0 2 2 2 0 Family of unknown function (DUF5347) Syndecan PF01034.20 EGC31628.1 - 2.5 8.1 4.6 5.7 6.9 4.6 1.6 1 0 0 1 1 1 0 Syndecan domain FNIP PF05725.12 EGC31629.1 - 5.4e-181 586.6 71.6 1.2e-16 60.6 0.4 14.5 13 1 2 15 15 15 15 FNIP Repeat Phage_min_tail PF05939.13 EGC31629.1 - 3.7e-05 24.1 0.0 14 6.1 0.0 7.0 7 2 1 8 8 8 2 Phage minor tail protein DUF3215 PF11503.8 EGC31629.1 - 1.3 8.9 3.7 24 4.9 0.0 5.0 6 0 0 6 6 6 0 Protein of unknown function (DUF3215) Myb_DNA-binding PF00249.31 EGC31631.1 - 2.7e-11 43.5 0.1 5.9e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC31631.1 - 5.1e-07 29.8 0.2 2e-06 28.0 0.2 2.1 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC31631.1 - 0.0017 18.2 0.4 0.0086 15.9 0.1 2.4 1 1 0 1 1 1 1 Myb DNA-binding like CompInhib_SCIN PF11546.8 EGC31631.1 - 0.26 11.4 2.6 0.74 9.9 2.6 1.7 1 0 0 1 1 1 0 Staphylococcal complement inhibitor SCIN Sedlin_N PF04628.13 EGC31632.1 - 4.1e-46 156.3 2.9 4.7e-46 156.2 2.9 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGC31632.1 - 1.9e-09 37.6 1.0 3.5e-07 30.3 0.3 2.1 2 0 0 2 2 2 2 Sybindin-like family Imm40 PF15569.6 EGC31632.1 - 0.033 14.3 0.4 3.2 7.9 0.2 2.2 2 0 0 2 2 2 0 Immunity protein 40 DUF508 PF04370.12 EGC31632.1 - 0.073 12.8 0.1 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF508) Tmemb_185A PF10269.9 EGC31634.1 - 2.4e-15 56.9 35.7 2.3e-08 34.0 12.7 3.1 2 1 1 3 3 3 3 Transmembrane Fragile-X-F protein F-box PF00646.33 EGC31634.1 - 0.018 14.9 0.1 0.04 13.8 0.1 1.7 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGC31634.1 - 0.036 13.9 0.0 0.11 12.5 0.0 1.9 1 0 0 1 1 1 0 F-box-like AnfG_VnfG PF03139.15 EGC31634.1 - 0.12 12.5 2.3 0.19 11.8 0.3 2.1 2 0 0 2 2 2 0 Vanadium/alternative nitrogenase delta subunit Y_phosphatase PF00102.27 EGC31635.1 - 1.4e-72 244.1 1.4 9.1e-72 241.4 0.1 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGC31635.1 - 0.00011 22.1 0.0 0.00011 22.1 0.0 3.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGC31635.1 - 0.16 12.1 0.8 3.8 7.6 0.0 3.3 4 0 0 4 4 4 0 Inositol hexakisphosphate EGF_2 PF07974.13 EGC31636.1 - 2.5e-08 34.1 64.9 0.00057 20.2 11.3 4.5 4 0 0 4 4 4 4 EGF-like domain TIG PF01833.24 EGC31636.1 - 9.6e-05 22.4 18.7 0.0053 16.8 1.1 3.8 3 0 0 3 3 3 2 IPT/TIG domain Ras PF00071.22 EGC31637.1 - 4.6e-59 198.6 0.0 5.5e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31637.1 - 9.3e-35 119.5 0.0 1.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31637.1 - 9.5e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC31637.1 - 1.3e-07 31.7 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC31637.1 - 2.6e-05 23.9 0.0 0.0002 20.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGC31637.1 - 9.3e-05 22.3 0.0 0.002 18.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EGC31637.1 - 0.00014 21.4 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC31637.1 - 0.0029 17.5 0.0 0.24 11.3 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGC31637.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGC31637.1 - 0.028 14.2 0.0 0.4 10.4 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGC31637.1 - 0.051 13.1 0.0 0.67 9.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 EGC31637.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain Y_phosphatase2 PF03162.13 EGC31638.1 - 1.2e-56 190.9 0.0 1.2e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGC31638.1 - 0.0033 17.4 0.0 0.0087 16.0 0.0 1.7 1 1 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGC31638.1 - 0.025 14.1 0.0 0.029 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.20 EGC31638.1 - 0.073 12.9 0.0 0.085 12.7 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LSM PF01423.22 EGC31640.1 - 1.6e-21 75.7 0.2 1.8e-21 75.6 0.2 1.0 1 0 0 1 1 1 1 LSM domain Abhydrolase_1 PF00561.20 EGC31641.1 - 1.6e-10 41.1 0.1 1.2e-09 38.2 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC31641.1 - 7.5e-10 38.5 0.0 1.1e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 BAAT_C PF08840.11 EGC31641.1 - 0.001 19.1 0.2 0.025 14.5 0.2 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGC31641.1 - 0.0092 16.6 0.0 0.022 15.4 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.13 EGC31641.1 - 0.052 13.2 0.0 4.2 7.0 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) MCM PF00493.23 EGC31643.1 - 7.3e-101 335.9 0.0 1.4e-100 335.0 0.0 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGC31643.1 - 1.8e-37 128.0 0.4 3.3e-37 127.1 0.4 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC31643.1 - 1.7e-22 79.6 0.2 4.4e-22 78.3 0.2 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGC31643.1 - 5.3e-16 59.1 2.9 6e-16 58.9 0.8 2.2 2 0 0 2 2 2 1 MCM N-terminal domain MCM6_C PF18263.1 EGC31643.1 - 2.9e-15 56.4 2.4 1.1e-14 54.5 2.4 2.1 1 0 0 1 1 1 1 MCM6 C-terminal winged-helix domain Mg_chelatase PF01078.21 EGC31643.1 - 3.8e-11 42.8 0.0 2.6e-08 33.5 0.0 3.2 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGC31643.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC31643.1 - 0.00014 21.8 0.0 0.00044 20.3 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGC31643.1 - 0.0038 17.0 0.0 0.0081 15.9 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain TPP_enzyme_N PF02776.18 EGC31644.1 - 1.6e-42 145.1 0.0 6.4e-42 143.1 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGC31644.1 - 1.7e-31 108.8 0.0 2.7e-31 108.1 0.0 1.3 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.21 EGC31644.1 - 2.7e-24 85.7 0.0 5.1e-22 78.3 0.0 2.9 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TILa PF12714.7 EGC31646.1 - 3.3 7.7 53.6 1.9 8.5 5.5 6.6 3 2 3 6 6 6 0 TILa domain DUF1754 PF08555.10 EGC31648.1 - 0.013 16.3 1.7 0.022 15.6 1.7 1.3 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) AMP-binding PF00501.28 EGC31649.1 - 0.1 11.1 0.0 0.1 11.1 0.0 1.2 1 0 0 1 1 1 0 AMP-binding enzyme AMP-binding PF00501.28 EGC31650.1 - 4e-65 220.1 0.0 5.1e-65 219.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC31650.1 - 1.2e-17 64.6 0.0 2e-17 63.9 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC31650.1 - 3.5e-13 49.3 1.0 7.8e-13 48.1 1.0 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus CREPT PF16566.5 EGC31651.1 - 9.7e-05 22.6 6.8 0.00011 22.4 6.8 1.1 1 0 0 1 1 1 1 Cell-cycle alteration and expression-elevated protein in tumour SPT16 PF08644.11 EGC31651.1 - 0.00069 19.8 4.7 0.00082 19.6 4.7 1.1 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Cauli_AT PF03233.13 EGC31651.1 - 0.011 15.7 2.0 0.014 15.3 2.0 1.2 1 0 0 1 1 1 0 Aphid transmission protein TFIIA PF03153.13 EGC31651.1 - 0.025 14.6 31.5 0.029 14.4 31.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 EGC31651.1 - 0.037 14.1 10.2 0.041 13.9 10.2 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 V_ATPase_I PF01496.19 EGC31651.1 - 0.08 10.8 8.3 0.098 10.6 8.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exo5 PF09810.9 EGC31651.1 - 0.11 11.9 7.3 0.13 11.8 7.3 1.1 1 0 0 1 1 1 0 Exonuclease V - a 5' deoxyribonuclease Suf PF05843.14 EGC31651.1 - 0.14 12.1 13.1 0.15 12.0 13.1 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF1840 PF08895.11 EGC31651.1 - 0.21 11.9 7.6 0.27 11.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF4175 PF13779.6 EGC31651.1 - 0.24 9.3 24.1 0.25 9.2 24.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 EGC31651.1 - 0.35 10.5 39.6 0.25 10.9 38.5 1.3 1 1 0 1 1 1 0 Spt20 family UPF0524 PF15823.5 EGC31651.1 - 0.36 10.2 3.6 0.4 10.0 3.6 1.1 1 0 0 1 1 1 0 UPF0524 of C3orf70 Band_3_cyto PF07565.13 EGC31651.1 - 0.49 10.2 6.5 0.55 10.0 6.5 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4407 PF14362.6 EGC31651.1 - 0.52 9.6 9.9 0.66 9.3 9.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2722 PF10846.8 EGC31651.1 - 0.77 8.6 24.9 1.1 8.1 24.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.16 EGC31651.1 - 0.89 9.6 4.7 0.92 9.5 4.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Activator_LAG-3 PF11498.8 EGC31651.1 - 1 8.3 37.2 1.4 7.8 37.2 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 DUF3533 PF12051.8 EGC31651.1 - 1.3 7.9 9.0 1.4 7.8 9.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) EIIBC-GUT_N PF03612.14 EGC31651.1 - 1.8 8.3 7.8 2.3 7.9 7.8 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus FAM60A PF15396.6 EGC31651.1 - 1.8 8.5 6.9 2 8.4 6.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF4834 PF16118.5 EGC31651.1 - 1.9 9.5 9.7 2.9 8.9 9.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGC31651.1 - 2.2 6.9 11.5 2.5 6.7 11.5 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGC31651.1 - 2.6 6.8 6.4 2.7 6.7 6.4 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter RmuC PF02646.16 EGC31651.1 - 2.9 6.9 16.4 3.8 6.6 16.4 1.1 1 0 0 1 1 1 0 RmuC family CemA PF03040.14 EGC31651.1 - 3.9 7.3 8.0 5.2 6.9 8.0 1.1 1 0 0 1 1 1 0 CemA family HemX PF04375.14 EGC31651.1 - 5 6.3 23.8 6.5 5.9 23.8 1.1 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase LMBR1 PF04791.16 EGC31651.1 - 5.3 5.8 10.1 6.1 5.6 10.1 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein UPF0560 PF10577.9 EGC31651.1 - 5.8 5.3 17.0 6.7 5.1 17.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 FAD-SLDH PF12318.8 EGC31651.1 - 6.9 6.7 12.1 11 6.0 11.9 1.5 1 1 0 1 1 1 0 Membrane bound FAD containing D-sorbitol dehydrogenase CLN3 PF02487.17 EGC31651.1 - 7.3 5.5 7.2 8.7 5.3 7.2 1.1 1 0 0 1 1 1 0 CLN3 protein FAM70 PF14967.6 EGC31651.1 - 7.4 5.9 8.1 8.2 5.8 8.1 1.1 1 0 0 1 1 1 0 FAM70 protein DUF3464 PF11947.8 EGC31651.1 - 7.6 6.3 10.6 11 5.8 10.6 1.2 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 CSG2 PF16965.5 EGC31651.1 - 7.6 5.4 7.6 9.4 5.1 7.6 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator ZYG-11_interact PF05884.12 EGC31651.1 - 8.1 5.8 7.5 9.4 5.6 7.5 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 GTA_holin_3TM PF11351.8 EGC31651.1 - 9.2 6.8 7.9 14 6.2 7.9 1.4 1 0 0 1 1 1 0 Holin of 3TMs, for gene-transfer release Presenilin PF01080.17 EGC31654.1 - 6.4 5.4 22.3 7.5 5.2 22.3 1.1 1 0 0 1 1 1 0 Presenilin Raftlin PF15250.6 EGC31654.1 - 6.9 5.3 14.7 8 5.1 14.7 1.0 1 0 0 1 1 1 0 Raftlin Peptidase_M56 PF05569.11 EGC31655.1 - 0.048 12.9 0.4 0.17 11.1 0.0 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 OAD_gamma PF04277.13 EGC31655.1 - 0.41 11.3 0.0 0.41 11.3 0.0 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Zip PF02535.22 EGC31655.1 - 3.1 6.9 6.2 8.5 5.5 2.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter tRNA_synthFbeta PF17759.1 EGC31656.1 - 7.7e-40 136.6 0.0 1.1e-39 136.1 0.0 1.2 1 0 0 1 1 1 1 Phenylalanyl tRNA synthetase beta chain CLM domain PhetRS_B1 PF18262.1 EGC31656.1 - 4.3e-33 113.4 0.5 1.8e-32 111.4 0.2 2.1 2 0 0 2 2 2 1 Phe-tRNA synthetase beta subunit B1 domain B3_4 PF03483.17 EGC31656.1 - 1.5e-24 86.6 0.1 3e-24 85.6 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.15 EGC31656.1 - 5.7e-20 71.4 0.2 3.6e-18 65.6 0.0 2.8 3 0 0 3 3 3 1 tRNA synthetase B5 domain LUD_dom PF02589.15 EGC31657.1 - 4.3e-32 111.4 0.5 4.9e-32 111.2 0.5 1.0 1 0 0 1 1 1 1 LUD domain DNA_pol_D_N PF18018.1 EGC31657.1 - 0.095 12.8 0.2 0.23 11.6 0.2 1.6 1 0 0 1 1 1 0 DNA polymerase delta subunit OB-fold domain Polysacc_synt_2 PF02719.15 EGC31657.1 - 0.16 11.1 3.6 0.16 11.1 0.3 2.3 2 1 1 3 3 3 0 Polysaccharide biosynthesis protein SAP PF02037.27 EGC31658.1 - 2e-08 33.8 0.0 5.9e-08 32.3 0.0 1.9 1 0 0 1 1 1 1 SAP domain Luteo_P1-P2 PF08467.10 EGC31658.1 - 0.0091 15.3 0.0 0.0091 15.3 0.0 1.9 2 0 0 2 2 2 1 Luteovirus RNA polymerase P1-P2/replicase EF-hand_6 PF13405.6 EGC31659.1 - 6.8e-11 41.2 0.8 0.22 11.6 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.32 EGC31659.1 - 6.5e-10 37.9 1.4 0.031 13.8 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.6 EGC31659.1 - 3.4e-09 37.0 3.8 1.2e-05 25.7 0.5 3.1 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC31659.1 - 1.9e-05 24.4 0.4 2.3 8.2 0.0 3.9 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC31659.1 - 0.042 14.2 4.9 5.4 7.4 2.3 2.8 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Nucleolin_bd PF16725.5 EGC31659.1 - 0.047 13.4 0.3 0.51 10.0 0.1 2.3 2 0 0 2 2 2 0 Nucleolin binding domain GH-E PF14410.6 EGC31659.1 - 0.077 13.4 0.9 1.8 9.0 0.2 2.7 3 0 0 3 3 3 0 HNH/ENDO VII superfamily nuclease with conserved GHE residues EF-hand_5 PF13202.6 EGC31659.1 - 0.12 12.0 2.4 6.8 6.4 0.0 3.2 3 0 0 3 3 3 0 EF hand ESP PF16590.5 EGC31659.1 - 1.8 8.9 4.8 2.5 8.4 2.3 2.3 2 1 1 3 3 3 0 Exocrine gland-secreting peptide Frag1 PF10277.9 EGC31660.1 - 7.8e-19 68.1 18.3 5.4e-18 65.3 11.6 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family DUF998 PF06197.13 EGC31660.1 - 0.013 15.1 0.2 0.02 14.5 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF1129 PF06570.11 EGC31660.1 - 0.49 9.8 4.7 0.79 9.2 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF2663 PF10864.8 EGC31660.1 - 6 7.3 8.2 1.6 9.2 2.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Gln-synt_C PF00120.24 EGC31662.1 - 2.1e-86 290.0 0.0 2.7e-86 289.7 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EGC31662.1 - 0.0017 18.2 0.0 0.0057 16.5 0.0 1.8 2 0 0 2 2 2 1 Glutamine synthetase N-terminal domain Fucokinase PF07959.12 EGC31663.1 - 9.5e-121 403.5 0.1 1.5e-120 402.9 0.1 1.3 1 0 0 1 1 1 1 L-fucokinase DUF1659 PF07872.11 EGC31663.1 - 0.039 13.6 0.5 0.12 12.1 0.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1659) RCC1 PF00415.18 EGC31664.1 - 2.4e-37 127.3 0.0 8.1e-10 39.2 0.0 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC31664.1 - 1.9e-23 81.7 12.7 2.5e-08 33.5 0.2 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Fe-S_biosyn PF01521.20 EGC31664.1 - 0.016 15.4 1.4 0.039 14.2 0.7 2.1 1 1 1 2 2 2 0 Iron-sulphur cluster biosynthesis SUKH-3 PF14433.6 EGC31664.1 - 0.021 15.3 0.1 0.51 10.8 0.1 2.6 2 0 0 2 2 2 0 SUKH-3 immunity protein EF-hand_1 PF00036.32 EGC31665.1 - 2e-19 67.6 1.3 1.8e-05 23.9 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGC31665.1 - 1.3e-15 57.6 1.0 7.3e-08 32.7 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC31665.1 - 3.6e-15 54.5 1.9 0.00011 21.8 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_5 PF13202.6 EGC31665.1 - 7.4e-11 41.0 2.8 7.8e-05 22.0 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGC31665.1 - 5.3e-10 39.0 4.5 2.5e-05 24.0 0.2 3.7 2 2 2 4 4 4 3 EF-hand domain pair Caleosin PF05042.13 EGC31665.1 - 0.001 19.0 0.0 0.0045 16.9 0.0 2.0 1 1 0 2 2 2 1 Caleosin related protein SPARC_Ca_bdg PF10591.9 EGC31665.1 - 0.01 16.2 1.1 0.56 10.6 0.1 2.1 1 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.6 EGC31665.1 - 0.015 15.2 0.9 3.9 7.4 0.1 2.5 2 0 0 2 2 2 0 EF hand Toprim_2 PF13155.6 EGC31665.1 - 0.02 15.3 0.1 1.4 9.4 0.0 2.5 2 1 1 3 3 3 0 Toprim-like EF-hand_9 PF14658.6 EGC31665.1 - 0.092 13.1 0.1 3.9 7.9 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain Glyco_transf_41 PF13844.6 EGC31666.1 - 6.2e-54 183.2 2.2 3.8e-30 104.8 0.1 2.7 3 0 0 3 3 3 2 Glycosyl transferase family 41 TPR_1 PF00515.28 EGC31666.1 - 2.3e-47 157.0 14.5 1.5e-08 34.1 0.2 7.9 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31666.1 - 3.9e-36 120.2 3.0 2.2e-05 24.2 0.1 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31666.1 - 1.1e-31 106.4 15.3 2.9e-07 30.2 0.0 7.8 7 1 0 7 7 7 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGC31666.1 - 1.9e-30 104.3 20.2 1.8e-08 33.9 0.0 7.5 3 1 4 7 7 7 7 TPR repeat TPR_17 PF13431.6 EGC31666.1 - 2.4e-27 93.3 24.0 0.00068 19.8 0.1 8.5 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31666.1 - 1.2e-21 76.7 0.6 0.0011 19.2 0.0 6.2 3 1 2 6 6 6 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31666.1 - 2.5e-21 74.1 0.9 0.0027 17.6 0.0 7.2 7 1 0 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGC31666.1 - 5.2e-17 62.2 0.0 3.3e-06 27.6 0.0 4.2 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGC31666.1 - 7.1e-15 54.3 8.0 0.011 15.6 0.0 7.1 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31666.1 - 1.4e-10 41.5 3.0 0.25 11.9 0.1 5.1 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31666.1 - 2e-10 40.6 0.0 0.54 11.2 0.0 5.6 2 2 3 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31666.1 - 1.4e-08 34.8 0.9 2.9 8.7 0.0 6.3 7 0 0 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC31666.1 - 6.4e-07 29.4 0.0 0.0043 17.2 0.0 3.6 2 1 0 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.12 EGC31666.1 - 0.0037 17.9 1.5 40 5.1 0.0 5.8 6 0 0 6 6 6 0 Sel1 repeat TPR_15 PF13429.6 EGC31666.1 - 0.0045 16.2 0.3 2.9 7.0 0.0 3.4 1 1 3 4 4 4 1 Tetratricopeptide repeat MIT PF04212.18 EGC31666.1 - 0.83 9.8 5.3 44 4.3 0.0 5.1 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain EST1_DNA_bind PF10373.9 EGC31666.1 - 1.3 8.4 21.8 2.3 7.6 2.0 4.0 2 1 0 2 2 2 0 Est1 DNA/RNA binding domain Ank_2 PF12796.7 EGC31670.1 - 3.1e-23 82.2 3.7 2.9e-09 37.4 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC31670.1 - 1.3e-21 76.7 4.4 3.6e-05 24.2 0.0 5.2 1 1 5 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC31670.1 - 3.6e-18 63.8 2.7 0.00077 19.7 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.6 EGC31670.1 - 3e-17 62.5 2.2 5.7e-08 32.9 0.0 4.8 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC31670.1 - 3.2e-13 49.5 4.5 1.3e-05 25.4 0.1 5.7 6 0 0 6 6 6 3 Ankyrin repeat Asp_protease_2 PF13650.6 EGC31670.1 - 0.16 12.6 0.2 1.8 9.3 0.0 2.2 1 1 1 2 2 2 0 Aspartyl protease Erf4 PF10256.9 EGC31671.1 - 4e-05 23.7 2.8 0.00026 21.1 2.5 2.3 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Comm PF15957.5 EGC31671.1 - 0.0068 16.7 0.0 0.01 16.2 0.0 1.5 1 0 0 1 1 1 1 Commissureless AA_permease_2 PF13520.6 EGC31671.1 - 0.018 13.9 3.9 0.023 13.6 3.9 1.1 1 0 0 1 1 1 0 Amino acid permease Erf4 PF10256.9 EGC31672.1 - 0.00012 22.2 1.0 0.00095 19.3 0.9 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Lyase_aromatic PF00221.19 EGC31673.1 - 8.1e-44 150.0 0.0 1e-42 146.4 0.0 2.1 1 1 0 1 1 1 1 Aromatic amino acid lyase DUF4969 PF16339.5 EGC31673.1 - 0.1 12.9 0.0 0.1 12.9 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4969) FA_hydroxylase PF04116.13 EGC31674.1 - 3.3e-27 95.4 15.9 3.3e-27 95.4 15.9 1.7 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily NFACT-R_1 PF05670.13 EGC31675.1 - 5.6e-41 139.6 0.2 1.6e-40 138.1 0.0 1.7 2 0 0 2 2 2 1 NFACT protein RNA binding domain Methyltransf_31 PF13847.6 EGC31676.1 - 4.7e-14 52.4 0.4 5.5e-14 52.2 0.4 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC31676.1 - 6.8e-14 52.3 0.0 9e-14 51.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC31676.1 - 1.7e-13 51.1 0.0 2.2e-13 50.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC31676.1 - 6e-06 26.9 0.0 7.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC31676.1 - 2.3e-05 24.0 0.0 3e-05 23.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.18 EGC31676.1 - 0.00044 19.7 0.1 0.00052 19.4 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGC31676.1 - 0.00044 20.1 0.0 0.0005 19.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGC31676.1 - 0.00098 18.6 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) TPMT PF05724.11 EGC31676.1 - 0.0084 15.8 0.0 0.012 15.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.16 EGC31676.1 - 0.011 14.9 0.1 0.013 14.7 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MetW PF07021.12 EGC31676.1 - 0.048 13.2 0.0 0.066 12.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HNH_3 PF13392.6 EGC31677.1 - 1.8e-12 46.8 3.6 3.6e-12 45.9 3.6 1.5 1 0 0 1 1 1 1 HNH endonuclease zf-CCHC_5 PF14787.6 EGC31677.1 - 1.1e-07 31.5 0.2 2.2e-07 30.4 0.2 1.6 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.23 EGC31677.1 - 0.00011 22.1 1.6 0.0002 21.3 1.6 1.4 1 0 0 1 1 1 1 Zinc knuckle Prog_receptor PF02161.15 EGC31678.1 - 0.12 11.1 4.0 0.075 11.8 1.6 1.7 1 1 1 2 2 2 0 Progesterone receptor EGF_2 PF07974.13 EGC31679.1 - 0.012 16.0 35.8 0.054 13.9 12.7 3.4 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 EGC31679.1 - 0.014 15.5 17.5 1.6 8.9 0.2 3.3 3 0 0 3 3 3 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC31679.1 - 0.094 12.8 15.1 0.16 12.1 4.3 2.8 2 0 0 2 2 2 0 Tenascin EGF domain OTU PF02338.19 EGC31680.1 - 8.9e-12 45.6 0.0 1.4e-11 44.9 0.0 1.3 1 0 0 1 1 1 1 OTU-like cysteine protease FNIP PF05725.12 EGC31681.1 - 1.6e-102 335.4 54.0 1.5e-13 50.7 0.4 12.4 10 2 2 12 12 12 11 FNIP Repeat DUF1769 PF08588.10 EGC31681.1 - 0.0043 17.2 5.7 0.34 11.2 0.1 5.7 7 2 0 7 7 7 1 Protein of unknown function (DUF1769) DUF5117 PF17148.4 EGC31682.1 - 0.051 13.4 0.8 1.2 8.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5117) Coiled PF05710.12 EGC31683.1 - 0.09 13.6 16.4 0.14 13.0 16.4 1.4 1 1 0 1 1 1 0 Coiled coil ECH_1 PF00378.20 EGC31684.1 - 1.8e-57 194.6 0.1 2.1e-57 194.3 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC31684.1 - 3.5e-27 95.8 0.1 2.2e-25 89.9 0.1 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase PGM_PMM_I PF02878.16 EGC31686.1 - 4.8e-39 133.2 0.3 7e-39 132.7 0.3 1.3 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.16 EGC31686.1 - 6.2e-29 100.5 0.0 1.1e-28 99.7 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.16 EGC31686.1 - 1.2e-13 51.5 0.0 3.4e-13 50.1 0.0 1.8 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.20 EGC31686.1 - 1.3e-05 25.3 0.0 3e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1882 PF08966.11 EGC31686.1 - 0.05 13.8 2.1 0.29 11.4 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) Amino_oxidase PF01593.24 EGC31688.1 - 1.8e-68 231.9 0.0 2.4e-68 231.5 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC31688.1 - 2e-16 60.0 0.1 4e-16 59.0 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGC31688.1 - 8.5e-10 38.3 0.1 4.2e-09 36.0 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain DAO PF01266.24 EGC31688.1 - 3.3e-09 36.8 0.3 5.2e-08 32.8 0.3 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGC31688.1 - 4.6e-08 32.7 0.1 0.001 18.4 0.1 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGC31688.1 - 3.5e-07 29.9 0.0 5.7e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGC31688.1 - 4e-06 25.8 0.0 4.2e-05 22.4 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EGC31688.1 - 6.4e-06 25.6 0.0 4.7e-05 22.8 0.0 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC31688.1 - 8.4e-06 25.2 0.6 1.5e-05 24.4 0.5 1.4 1 1 0 1 1 1 1 Thi4 family GIDA PF01134.22 EGC31688.1 - 8.6e-06 25.1 0.0 1.7e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Pyr_redox PF00070.27 EGC31688.1 - 5e-05 23.8 0.1 0.00016 22.2 0.1 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGC31688.1 - 0.00021 20.5 0.0 0.00047 19.3 0.0 1.5 2 0 0 2 2 2 1 Lycopene cyclase protein FAD_binding_3 PF01494.19 EGC31688.1 - 0.00067 19.0 0.1 0.0011 18.3 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain AlaDh_PNT_C PF01262.21 EGC31688.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain GDI PF00996.18 EGC31688.1 - 0.014 13.9 0.2 0.07 11.6 0.0 2.1 3 0 0 3 3 3 0 GDP dissociation inhibitor Laminin_G_3 PF13385.6 EGC31689.1 - 3.6e-10 40.2 0.5 1.4e-09 38.3 0.1 2.2 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Fn3_assoc PF13287.6 EGC31689.1 - 2e-07 31.1 4.8 0.001 19.2 0.1 3.5 3 0 0 3 3 3 2 Fn3 associated F5_F8_type_C PF00754.25 EGC31689.1 - 4.1e-06 26.9 0.0 1e-05 25.7 0.0 1.7 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.6 EGC31689.1 - 5.3e-06 26.3 5.4 0.021 14.8 0.4 3.0 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain ILEI PF15711.5 EGC31690.1 - 2e-15 57.1 0.7 1.1e-14 54.6 0.3 2.5 2 0 0 2 2 2 1 Interleukin-like EMT inducer Spc24 PF08286.11 EGC31690.1 - 0.019 15.2 0.1 0.019 15.2 0.1 3.4 3 1 0 3 3 3 0 Spc24 subunit of Ndc80 GFA PF04828.14 EGC31691.1 - 1.1e-05 25.6 0.2 1.1e-05 25.6 0.2 2.1 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FUR PF01475.19 EGC31691.1 - 0.0028 17.8 0.3 0.0038 17.4 0.3 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family MDM31_MDM32 PF08118.11 EGC31692.1 - 3.2e-90 303.3 28.8 4.9e-36 124.5 0.4 5.3 3 2 1 5 5 5 4 Yeast mitochondrial distribution and morphology (MDM) proteins NOA36 PF06524.12 EGC31692.1 - 6.5 6.0 10.3 13 5.0 10.3 1.5 1 0 0 1 1 1 0 NOA36 protein PALP PF00291.25 EGC31693.1 - 6.4e-74 249.0 0.0 7.2e-74 248.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RhoGEF PF00621.20 EGC31694.1 - 5.4e-47 160.4 0.1 5.4e-47 160.4 0.1 3.5 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGC31694.1 - 2.7e-07 31.0 0.5 1.6e-06 28.6 0.1 2.6 2 0 0 2 2 2 1 PH domain IQ PF00612.27 EGC31694.1 - 0.01 15.5 1.6 0.026 14.3 1.6 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif CBS PF00571.28 EGC31695.1 - 8.7e-20 70.9 4.8 5e-08 33.3 0.0 4.9 5 0 0 5 5 5 4 CBS domain AA_permease_2 PF13520.6 EGC31696.1 - 7.7e-48 163.4 57.4 7.7e-48 163.4 57.4 1.5 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC31696.1 - 2.7e-40 138.4 46.2 2.7e-40 138.4 46.2 1.5 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.6 EGC31696.1 - 6.1e-17 61.4 3.1 6.1e-17 61.4 3.1 4.0 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.13 EGC31696.1 - 5.9e-05 22.1 17.7 5.9e-05 22.1 17.7 3.3 2 2 1 3 3 3 1 Spore germination protein Lung_7-TM_R PF06814.13 EGC31697.1 - 9.9e-15 54.5 19.0 9.9e-15 54.5 19.0 2.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EGC31697.1 - 4.8e-05 22.9 22.9 4.8e-05 22.9 22.9 2.7 3 1 1 4 4 4 1 Rhodopsin-like GPCR transmembrane domain DUF4199 PF13858.6 EGC31697.1 - 0.018 15.5 14.2 0.018 15.5 14.2 3.8 2 1 2 4 4 4 0 Protein of unknown function (DUF4199) DUF2572 PF10833.8 EGC31698.1 - 1.1 9.0 9.7 0.26 11.0 5.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2572) DUF229 PF02995.17 EGC31699.1 - 9.6e-44 149.8 0.5 4.2e-43 147.7 0.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.23 EGC31699.1 - 0.0019 17.6 0.1 0.024 14.1 0.0 2.3 2 1 0 3 3 3 1 Sulfatase RasGEF_N PF00618.20 EGC31699.1 - 0.31 11.3 5.7 1.5 9.1 5.7 2.3 1 1 0 1 1 1 0 RasGEF N-terminal motif ETRAMP PF09716.10 EGC31699.1 - 1.5 8.9 7.9 38 4.5 4.7 3.0 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.12 EGC31700.1 - 3.2e-29 100.8 9.4 1.3e-10 41.3 0.1 3.4 3 0 0 3 3 3 3 FNIP Repeat FNIP PF05725.12 EGC31703.1 - 3.8e-186 603.1 58.6 1.6e-15 57.0 0.4 15.2 10 2 4 16 16 16 16 FNIP Repeat Oxidored_FMN PF00724.20 EGC31705.1 - 3.8e-09 36.3 0.0 4.6e-09 36.0 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_1 PF00076.22 EGC31706.1 - 8.5e-06 25.5 0.0 2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC31706.1 - 6.5e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGC31706.1 - 0.00062 19.7 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif YtxH PF12732.7 EGC31706.1 - 0.98 10.0 4.2 18 5.9 1.4 2.6 2 0 0 2 2 2 0 YtxH-like protein Methyltransf_16 PF10294.9 EGC31708.1 - 6.5e-17 61.8 0.0 8.8e-17 61.4 0.0 1.2 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC31708.1 - 3.1e-06 27.1 0.0 4.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC31708.1 - 0.0012 18.7 0.2 0.019 14.8 0.2 2.2 1 1 0 1 1 1 1 Methyltransferase domain MRJP PF03022.16 EGC31708.1 - 0.007 15.8 0.1 0.041 13.2 0.0 1.9 2 0 0 2 2 2 1 Major royal jelly protein Methyltransf_12 PF08242.12 EGC31708.1 - 0.022 15.5 0.0 0.055 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGC31708.1 - 0.023 15.4 0.0 0.3 11.8 0.0 2.3 1 1 0 1 1 1 0 Methyltransferase domain GidB PF02527.15 EGC31708.1 - 0.038 13.3 0.0 0.069 12.5 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_11 PF08241.12 EGC31708.1 - 0.04 14.6 0.0 0.27 11.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain CheR PF01739.18 EGC31708.1 - 0.1 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.13 EGC31708.1 - 0.11 11.8 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CLN3 PF02487.17 EGC31709.1 - 2.5e-54 184.8 14.1 8.2e-53 179.9 14.1 2.0 1 1 0 1 1 1 1 CLN3 protein HEAT PF02985.22 EGC31710.1 - 6.9e-17 60.1 0.3 0.18 12.1 0.0 8.5 9 0 0 9 9 9 5 HEAT repeat HEAT_EZ PF13513.6 EGC31710.1 - 3.5e-09 37.0 0.7 1.1 9.8 0.0 7.6 9 0 0 9 9 9 2 HEAT-like repeat HEAT_2 PF13646.6 EGC31710.1 - 1.1e-08 35.4 0.0 0.44 11.0 0.0 7.0 8 0 0 8 8 8 2 HEAT repeats Cnd1 PF12717.7 EGC31710.1 - 1.2e-06 28.7 8.5 0.011 15.7 1.8 6.0 6 0 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGC31710.1 - 1.2e-05 25.8 0.6 0.066 13.8 0.0 5.5 5 0 0 5 5 5 1 Vacuolar 14 Fab1-binding region RTP1_C1 PF10363.9 EGC31710.1 - 2.3e-05 24.5 1.6 0.13 12.4 0.1 4.9 4 0 0 4 4 4 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF2573 PF10835.8 EGC31710.1 - 0.02 15.2 0.0 0.17 12.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Adaptin_N PF01602.20 EGC31710.1 - 0.45 9.0 16.8 0.065 11.8 0.8 4.9 5 1 0 5 5 5 0 Adaptin N terminal region Transferase PF02458.15 EGC31711.1 - 2.9e-08 32.8 0.0 4e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family RasGAP PF00616.19 EGC31712.1 - 8.8e-29 100.7 3.8 8.8e-29 100.7 3.8 7.0 5 3 1 6 6 6 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.18 EGC31712.1 - 2.1e-22 79.3 0.3 8.3e-22 77.4 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Rgp1 PF08737.10 EGC31713.1 - 4e-39 135.0 11.5 2.1e-24 86.5 0.9 3.1 2 1 1 3 3 3 2 Rgp1 Bcr-Abl_Oligo PF09036.10 EGC31714.1 - 0.0042 17.1 0.3 0.012 15.7 0.3 1.7 1 0 0 1 1 1 1 Bcr-Abl oncoprotein oligomerisation domain CIAPIN1 PF05093.13 EGC31714.1 - 0.016 15.7 3.4 0.074 13.6 3.4 2.2 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Endonuc_Holl PF10107.9 EGC31714.1 - 0.13 12.1 4.6 0.28 11.0 4.6 1.4 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase DUF3464 PF11947.8 EGC31714.1 - 0.14 11.9 3.6 0.49 10.1 3.6 2.0 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 ATP-synt_ab PF00006.25 EGC31715.1 - 6.5e-69 231.8 0.0 9.4e-69 231.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGC31715.1 - 3.2e-10 40.4 0.5 6.8e-10 39.3 0.5 1.6 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain Rad10 PF03834.14 EGC31715.1 - 0.13 12.3 0.0 0.27 11.3 0.0 1.5 1 0 0 1 1 1 0 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) Ribosomal_L1 PF00687.21 EGC31717.1 - 7.5e-45 153.2 5.1 9.6e-45 152.8 5.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family Fib_alpha PF08702.10 EGC31717.1 - 0.088 13.0 1.4 6 7.0 0.1 2.8 2 2 0 2 2 2 0 Fibrinogen alpha/beta chain family HSP90 PF00183.18 EGC31718.1 - 7.4e-97 325.4 17.8 2.9e-95 320.1 5.4 2.4 2 1 1 3 3 3 2 Hsp90 protein HATPase_c PF02518.26 EGC31718.1 - 1.4e-08 35.3 1.6 1.9e-08 34.8 0.2 2.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGC31718.1 - 2.8e-08 33.7 0.0 1e-07 31.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Chlorophyllase2 PF12740.7 EGC31718.1 - 0.1 11.5 0.0 0.17 10.8 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Cpn60_TCP1 PF00118.24 EGC31719.1 - 1.5e-167 558.2 0.5 1.7e-167 558.0 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.22 EGC31720.1 - 2.3e-56 189.8 0.1 2.3e-56 189.8 0.1 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGC31720.1 - 4.6e-31 107.5 0.0 4.6e-31 107.5 0.0 2.3 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31720.1 - 9.4e-15 54.5 0.1 1.6e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family ATP_bind_1 PF03029.17 EGC31720.1 - 4.8e-05 23.3 1.3 6.6e-05 22.8 0.8 1.5 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.27 EGC31720.1 - 0.00013 21.5 6.3 0.00029 20.4 4.8 2.3 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Glycos_transf_1 PF00534.20 EGC31720.1 - 0.0025 17.4 2.4 0.039 13.5 2.4 2.1 1 1 0 1 1 1 1 Glycosyl transferases group 1 MMR_HSR1 PF01926.23 EGC31720.1 - 0.0062 16.6 0.8 0.018 15.1 0.5 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase MnmE_helical PF12631.7 EGC31720.1 - 0.0083 16.3 0.4 0.0099 16.1 0.4 1.2 1 0 0 1 1 1 1 MnmE helical domain YwhD PF08741.10 EGC31720.1 - 0.019 14.6 0.2 0.019 14.6 0.2 2.0 1 1 1 2 2 2 0 YwhD family DNA_pol_E_B PF04042.16 EGC31720.1 - 0.05 13.0 0.1 0.098 12.0 0.0 1.5 1 1 0 1 1 1 0 DNA polymerase alpha/epsilon subunit B DUF2491 PF10679.9 EGC31720.1 - 0.58 9.3 8.4 0.8 8.9 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) RsgA_GTPase PF03193.16 EGC31720.1 - 1.2 9.0 9.1 0.43 10.5 0.5 3.0 2 1 1 3 3 3 0 RsgA GTPase ALMT PF11744.8 EGC31720.1 - 7.4 5.3 11.9 11 4.7 11.9 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter YqzH PF14164.6 EGC31720.1 - 7.5 6.7 11.8 60 3.8 8.5 2.6 1 1 1 2 2 2 0 YqzH-like protein Pkinase PF00069.25 EGC31721.1 - 6.5e-77 258.5 0.1 8.3e-77 258.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31721.1 - 8.8e-38 130.1 0.0 1.3e-37 129.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Haspin_kinase PF12330.8 EGC31721.1 - 5.1e-07 29.0 2.6 8.4e-07 28.3 2.6 1.3 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGC31721.1 - 1.5e-06 27.3 0.8 2.4e-06 26.6 0.1 1.6 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGC31721.1 - 3.5e-06 26.6 0.0 8.4e-05 22.0 0.0 2.4 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.22 EGC31721.1 - 0.00031 20.4 0.4 0.00071 19.2 0.4 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGC31721.1 - 0.0037 17.2 0.1 0.0056 16.6 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC31721.1 - 0.011 15.2 0.2 0.017 14.5 0.2 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NotI PF12183.8 EGC31721.1 - 0.064 12.6 0.1 0.43 9.9 0.0 2.0 2 0 0 2 2 2 0 Restriction endonuclease NotI Pkinase_C PF00433.24 EGC31721.1 - 0.092 13.5 1.0 0.092 13.5 1.0 2.5 2 1 0 2 2 2 0 Protein kinase C terminal domain Cpn60_TCP1 PF00118.24 EGC31722.1 - 2.9e-167 557.2 0.5 3.3e-167 557.1 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.28 EGC31723.1 - 3.6e-20 72.3 2.8 4e-20 72.2 2.8 1.0 1 0 0 1 1 1 1 Carboxylesterase family Clathrin_lg_ch PF01086.17 EGC31724.1 - 8.1e-23 81.7 12.8 9e-23 81.5 12.8 1.0 1 0 0 1 1 1 1 Clathrin light chain DUF4407 PF14362.6 EGC31724.1 - 0.93 8.8 4.7 1.1 8.5 4.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Ashwin PF15323.6 EGC31724.1 - 4.2 7.3 14.5 0.33 11.0 9.1 1.7 1 1 1 2 2 2 0 Developmental protein SURF6 PF04935.12 EGC31725.1 - 6 6.6 11.3 12 5.6 6.9 2.4 2 0 0 2 2 2 0 Surfeit locus protein 6 DUF359 PF04019.12 EGC31725.1 - 8.4 6.1 6.4 6.5 6.4 2.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF359) TerD PF02342.18 EGC31726.1 - 4.1e-72 241.6 0.0 4.9e-72 241.4 0.0 1.0 1 0 0 1 1 1 1 TerD domain Drf_FH1 PF06346.12 EGC31726.1 - 0.19 11.4 30.2 0.28 10.9 30.2 1.2 1 0 0 1 1 1 0 Formin Homology Region 1 Ammonium_transp PF00909.21 EGC31727.1 - 2.8e-108 362.2 27.2 3.1e-108 362.0 27.2 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4972 PF16342.5 EGC31728.1 - 0.0021 17.7 1.8 0.0053 16.5 1.8 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4972) Sid-5 PF17204.3 EGC31728.1 - 0.24 11.6 0.0 0.24 11.6 0.0 3.5 2 1 1 3 3 3 0 Sid-5 family DUF4064 PF13273.6 EGC31729.1 - 0.026 14.8 1.1 0.026 14.8 1.1 6.3 5 2 2 7 7 7 0 Protein of unknown function (DUF4064) DNase_II PF03265.15 EGC31731.1 - 2e-20 73.4 19.7 2.4e-15 56.6 6.6 3.2 2 1 1 3 3 3 3 Deoxyribonuclease II Vps52 PF04129.12 EGC31732.1 - 3.5e-67 227.3 27.4 2.2e-65 221.3 27.4 2.4 1 1 0 1 1 1 1 Vps52 / Sac2 family UPF0449 PF15136.6 EGC31732.1 - 0.041 14.3 0.8 0.041 14.3 0.8 3.0 3 0 0 3 3 3 0 Uncharacterised protein family UPF0449 PRRSV_2b PF07069.11 EGC31732.1 - 0.65 10.5 3.1 1 9.9 1.5 2.2 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b DUF1664 PF07889.12 EGC31732.1 - 0.83 9.7 5.0 2.3 8.2 0.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Ku_PK_bind PF08785.11 EGC31732.1 - 1.8 8.7 5.7 0.92 9.7 1.5 2.8 3 0 0 3 3 3 0 Ku C terminal domain like DUF1722 PF08349.11 EGC31732.1 - 2.7 8.3 9.2 3 8.2 0.1 3.9 3 2 1 4 4 4 0 Protein of unknown function (DUF1722) NYD-SP28 PF14772.6 EGC31732.1 - 6.3 6.9 12.2 3.7 7.6 0.1 4.3 3 1 1 4 4 4 0 Sperm tail T6PP_N PF18572.1 EGC31732.1 - 6.5 6.7 9.5 2.5 8.0 4.6 2.9 3 1 0 3 3 3 0 Trehalose-6-phosphate phosphatase N-terminal helical bundle domain EFG_IV PF03764.18 EGC31733.1 - 4.2e-26 91.1 0.0 2.1e-25 88.9 0.0 2.1 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU PF00009.27 EGC31733.1 - 1.1e-24 87.0 0.0 8.7e-21 74.4 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGC31733.1 - 2.5e-10 40.3 0.0 5.7e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC31733.1 - 3.6e-06 27.3 0.1 1.5e-05 25.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 G-alpha PF00503.20 EGC31733.1 - 0.00014 21.2 1.1 0.015 14.5 0.0 2.6 2 0 0 2 2 2 2 G-protein alpha subunit FNIP PF05725.12 EGC31734.1 - 2.3e-11 43.7 17.2 1.1e-06 28.6 0.3 6.2 3 2 2 5 5 5 3 FNIP Repeat DUF1725 PF08333.11 EGC31734.1 - 0.23 11.2 1.7 9.1 6.1 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1725) Ras PF00071.22 EGC31735.1 - 4e-60 202.1 0.0 4.6e-60 201.9 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31735.1 - 5.5e-21 75.0 0.0 7.7e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31735.1 - 1.4e-09 37.7 0.0 1.7e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC31735.1 - 2.9e-06 27.0 0.2 1.9e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC31735.1 - 0.00011 22.1 0.1 0.57 10.1 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC31735.1 - 0.00013 22.0 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.17 EGC31735.1 - 0.0095 15.7 0.9 0.098 12.4 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Septin PF00735.18 EGC31735.1 - 0.023 14.0 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EGC31735.1 - 0.049 13.2 0.1 0.27 10.7 0.1 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Glyco_transf_10 PF00852.19 EGC31736.1 - 3.7e-35 121.2 0.4 3.7e-35 121.2 0.4 1.9 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Glyco_trans_1_2 PF13524.6 EGC31736.1 - 3e-05 24.3 0.0 7.5e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 EMC3_TMCO1 PF01956.16 EGC31736.1 - 0.05 13.3 2.4 0.093 12.5 2.4 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like O-antigen_lig PF13425.6 EGC31736.1 - 0.055 12.2 14.1 0.089 11.6 14.1 1.4 1 0 0 1 1 1 0 O-antigen ligase like membrane protein CLN3 PF02487.17 EGC31736.1 - 0.15 11.0 0.5 0.23 10.4 0.5 1.2 1 0 0 1 1 1 0 CLN3 protein DUF5334 PF17268.2 EGC31736.1 - 0.22 11.9 1.7 3.9 7.8 0.0 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5334) Ac76 PF05814.11 EGC31736.1 - 0.34 10.9 11.2 0.41 10.7 9.0 2.3 2 0 0 2 2 2 0 Orf76 (Ac76) 7TM_GPCR_Sru PF10322.9 EGC31736.1 - 1.4 8.1 5.7 2.3 7.5 5.7 1.3 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru UCH PF00443.29 EGC31737.1 - 7e-76 255.1 3.3 1.8e-75 253.8 3.3 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGC31737.1 - 1.7e-15 57.4 0.0 1.7e-15 57.4 0.0 4.0 4 2 0 4 4 4 1 DUSP domain Ubiquitin_3 PF14836.6 EGC31737.1 - 6.9e-05 22.8 0.0 0.00018 21.4 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Mito_carr PF00153.27 EGC31738.1 - 1.2e-49 166.1 7.7 1.4e-19 69.7 0.4 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein TAFH PF07531.14 EGC31740.1 - 0.013 15.6 1.3 0.034 14.3 1.3 1.9 1 0 0 1 1 1 0 NHR1 homology to TAF DUF948 PF06103.11 EGC31740.1 - 0.082 13.2 6.2 0.87 9.9 1.9 3.3 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) GNAT_acetyltr_2 PF13718.6 EGC31740.1 - 3 7.2 9.5 7.6 5.9 1.3 2.5 2 0 0 2 2 2 0 GNAT acetyltransferase 2 SKG6 PF08693.10 EGC31741.1 - 3.2e-06 26.5 3.5 6.1e-06 25.6 3.5 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGC31741.1 - 0.0028 18.0 13.7 0.0028 18.0 13.7 2.9 2 0 0 2 2 2 1 EGF-like domain LicD PF04991.13 EGC31741.1 - 0.052 13.7 0.5 0.052 13.7 0.5 2.3 3 0 0 3 3 3 0 LicD family Adeno_E3_CR2 PF02439.15 EGC31741.1 - 0.86 9.4 5.8 1.6 8.5 5.8 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Phosphodiest PF01663.22 EGC31742.1 - 3.4e-79 267.0 0.2 4.2e-79 266.7 0.2 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGC31742.1 - 1.5e-07 31.1 3.8 8.9e-06 25.3 0.1 2.7 2 1 0 3 3 3 2 Sulfatase PglZ PF08665.12 EGC31742.1 - 9.2e-05 22.6 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 PglZ domain DUF4577 PF15145.6 EGC31742.1 - 0.034 14.2 0.0 0.074 13.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4577) CS PF04969.16 EGC31743.1 - 0.00017 22.5 0.0 0.00021 22.2 0.0 1.1 1 0 0 1 1 1 1 CS domain CS PF04969.16 EGC31744.1 - 0.00036 21.5 0.1 0.00072 20.5 0.0 1.5 2 0 0 2 2 2 1 CS domain Phosphodiest PF01663.22 EGC31745.1 - 3.6e-70 237.3 2.2 2.1e-69 234.8 2.2 1.9 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGC31745.1 - 5.7e-10 39.1 0.0 2.8e-08 33.5 0.0 2.4 2 0 0 2 2 2 1 Sulfatase Glycophorin_A PF01102.18 EGC31745.1 - 0.022 15.0 0.0 0.049 13.9 0.0 1.6 1 0 0 1 1 1 0 Glycophorin A PglZ PF08665.12 EGC31745.1 - 0.08 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 PglZ domain DUF1501 PF07394.12 EGC31745.1 - 0.15 11.1 0.0 0.22 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Phosphodiest PF01663.22 EGC31746.1 - 9.1e-75 252.5 0.5 1.1e-74 252.2 0.5 1.1 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGC31746.1 - 2e-08 34.0 0.1 1.1e-07 31.6 0.1 2.1 1 1 0 1 1 1 1 Sulfatase DUF1501 PF07394.12 EGC31746.1 - 0.018 14.1 0.0 0.03 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) PglZ PF08665.12 EGC31746.1 - 0.044 13.9 0.0 0.1 12.7 0.0 1.6 1 0 0 1 1 1 0 PglZ domain Pterin_bind PF00809.22 EGC31746.1 - 0.16 11.6 0.0 0.3 10.7 0.0 1.4 1 0 0 1 1 1 0 Pterin binding enzyme Vps53_N PF04100.12 EGC31747.1 - 3.8e-111 371.7 14.7 7.9e-111 370.7 13.4 2.2 2 1 0 2 2 2 1 Vps53-like, N-terminal Vps54_N PF10475.9 EGC31747.1 - 2e-12 47.0 7.6 7.9e-11 41.8 6.5 2.4 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EGC31747.1 - 0.00019 21.5 2.2 0.0006 19.9 1.4 2.3 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 COG5 PF10392.9 EGC31747.1 - 0.0003 21.0 1.8 0.0012 19.0 1.8 2.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 DUF2052 PF09747.9 EGC31747.1 - 0.016 15.4 7.2 0.042 14.0 7.2 1.7 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Mis12 PF05859.12 EGC31747.1 - 0.064 13.3 3.1 7.5 6.6 0.0 4.1 4 1 0 4 4 4 0 Mis12 protein Mfa1 PF17445.2 EGC31747.1 - 0.23 11.5 0.5 0.43 10.6 0.5 1.4 1 0 0 1 1 1 0 Mating factor A1 DDHD PF02862.17 EGC31747.1 - 0.84 9.8 5.5 0.23 11.6 1.5 2.1 2 0 0 2 2 2 0 DDHD domain Herpes_DNAp_acc PF04929.12 EGC31747.1 - 1.4 7.8 5.4 2.2 7.2 5.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Presenilin PF01080.17 EGC31747.1 - 3.3 6.4 6.7 5.3 5.7 6.7 1.2 1 0 0 1 1 1 0 Presenilin C2 PF00168.30 EGC31748.1 - 0.034 14.4 0.0 0.06 13.6 0.0 1.4 1 0 0 1 1 1 0 C2 domain HTH_Tnp_4 PF13613.6 EGC31748.1 - 0.047 13.4 0.3 0.41 10.4 0.2 2.3 2 1 1 3 3 3 0 Helix-turn-helix of DDE superfamily endonuclease EGF_Tenascin PF18720.1 EGC31749.1 - 0.0047 17.0 4.8 0.013 15.5 4.8 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGC31749.1 - 0.024 15.0 13.2 0.072 13.5 13.2 1.9 1 0 0 1 1 1 0 EGF-like domain EXS PF03124.14 EGC31750.1 - 2.7e-77 260.3 17.9 3.4e-77 260.0 17.9 1.0 1 0 0 1 1 1 1 EXS family zinc_ribbon_10 PF10058.9 EGC31751.1 - 1.7e-10 40.4 1.4 1.8e-10 40.3 0.2 1.7 2 0 0 2 2 2 1 Predicted integral membrane zinc-ribbon metal-binding protein Herpes_LMP2 PF07415.11 EGC31751.1 - 0.36 9.6 1.8 0.46 9.2 1.8 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein DUF3381 PF11861.8 EGC31751.1 - 4.7 7.0 11.6 0.15 11.8 5.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3381) Aminotran_1_2 PF00155.21 EGC31753.1 - 1.5e-34 119.7 0.0 2.1e-34 119.3 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGC31753.1 - 0.027 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase OTU PF02338.19 EGC31754.1 - 1.4e-20 74.1 1.0 1.6e-20 73.8 0.1 1.5 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGC31754.1 - 5.6e-06 26.0 3.1 0.028 13.8 0.0 2.3 1 1 1 2 2 2 2 Peptidase C65 Otubain PP28 PF10252.9 EGC31755.1 - 1.5e-12 47.8 21.4 1.5e-12 47.8 21.4 3.2 2 2 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 Nop53 PF07767.11 EGC31755.1 - 0.11 11.9 39.6 0.15 11.4 39.6 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) tRNA_m1G_MT PF01746.21 EGC31756.1 - 2.1e-23 83.1 0.0 1.9e-22 79.9 0.0 2.2 1 1 0 1 1 1 1 tRNA (Guanine-1)-methyltransferase F5_F8_type_C PF00754.25 EGC31757.1 - 6.3e-24 84.5 2.8 1.1e-23 83.7 2.8 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC31757.1 - 3.7e-20 71.9 3.9 5.4e-20 71.3 0.7 2.3 2 0 0 2 2 2 1 H-type lectin domain pXO2-34 PF17362.2 EGC31757.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.5 1 0 0 1 1 1 0 Family of unknown function DUF3012 PF11216.8 EGC31757.1 - 0.059 13.4 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) Endotoxin_N PF03945.14 EGC31758.1 - 1.3e-45 155.8 9.6 1.3e-45 155.8 9.6 2.0 1 1 1 2 2 2 1 delta endotoxin, N-terminal domain Endotoxin_C PF03944.14 EGC31758.1 - 2.1e-05 24.9 1.4 2.1e-05 24.9 1.4 3.0 3 1 0 3 3 3 1 delta endotoxin HSP70 PF00012.20 EGC31759.1 - 2.3e-94 316.7 16.0 2.3e-94 316.7 16.0 3.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.13 EGC31759.1 - 6.2e-05 22.0 0.2 6.2e-05 22.0 0.2 2.6 3 1 0 3 3 3 1 MreB/Mbl protein Rrp44_CSD1 PF17216.3 EGC31759.1 - 0.0096 15.6 0.4 0.025 14.3 0.4 1.6 1 0 0 1 1 1 1 Rrp44-like cold shock domain Endotoxin_N PF03945.14 EGC31760.1 - 1.2e-05 25.2 0.0 0.0025 17.6 0.0 2.3 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain DUF971 PF06155.12 EGC31760.1 - 0.048 14.3 0.0 0.13 12.9 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF971) OTU PF02338.19 EGC31761.1 - 5e-12 46.4 0.0 5e-12 46.4 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease LIP PF03583.14 EGC31762.1 - 0.25 10.6 1.3 0.97 8.7 0.3 2.4 2 1 0 3 3 3 0 Secretory lipase Ribosomal_L27A PF00828.19 EGC31763.1 - 0.13 12.9 0.8 0.94 10.2 0.1 2.8 2 0 0 2 2 2 0 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Tetraspanin PF00335.20 EGC31764.1 - 0.023 14.4 12.7 0.58 9.8 2.0 3.3 3 0 0 3 3 3 0 Tetraspanin family Amastin PF07344.11 EGC31764.1 - 0.025 14.4 0.3 0.025 14.4 0.3 2.6 2 1 0 2 2 2 0 Amastin surface glycoprotein DUF3611 PF12263.8 EGC31764.1 - 0.031 14.2 0.8 0.031 14.2 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) DUF4064 PF13273.6 EGC31764.1 - 0.035 14.4 2.7 0.035 14.4 2.7 4.3 3 1 2 5 5 5 0 Protein of unknown function (DUF4064) Phage_holin_2_3 PF16080.5 EGC31764.1 - 0.082 12.7 6.6 9.6 6.0 0.0 4.6 4 0 0 4 4 4 0 Bacteriophage holin family HP1 SLATT_4 PF18186.1 EGC31764.1 - 0.083 12.5 0.3 0.29 10.7 0.0 2.1 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 4 Claudin_2 PF13903.6 EGC31764.1 - 0.21 11.3 11.6 0.07 12.9 2.5 2.9 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ndc1_Nup PF09531.10 EGC31764.1 - 3.4 6.2 14.4 0.12 11.1 2.7 2.0 2 0 0 2 2 2 0 Nucleoporin protein Ndc1-Nup PMP22_Claudin PF00822.20 EGC31764.1 - 5.1 6.9 12.8 3 7.7 0.4 3.6 3 1 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family Acetyltransf_3 PF13302.7 EGC31765.1 - 4.5e-18 66.3 0.0 6e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC31765.1 - 7.9e-07 29.3 0.0 1.7e-06 28.3 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC31765.1 - 0.0018 18.7 0.2 0.0031 17.9 0.1 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HATPase_c_5 PF14501.6 EGC31765.1 - 0.0023 17.8 1.2 0.018 14.9 0.1 2.3 1 1 1 2 2 2 1 GHKL domain DUF4070 PF13282.6 EGC31767.1 - 0.15 12.2 4.4 1.7 8.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4070) SAP PF02037.27 EGC31768.1 - 0.0043 16.8 0.0 0.0063 16.2 0.0 1.3 1 0 0 1 1 1 1 SAP domain RGS PF00615.19 EGC31769.1 - 3.1e-19 69.4 6.7 9.9e-11 41.9 2.5 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain HAD_2 PF13419.6 EGC31770.1 - 0.049 13.7 3.3 0.12 12.5 1.4 2.0 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase ATPase PF06745.13 EGC31770.1 - 0.094 12.0 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 KaiC DUF3641 PF12345.8 EGC31770.1 - 0.16 12.0 5.0 2.2 8.3 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3641) ANAPC4_WD40 PF12894.7 EGC31771.1 - 3.6e-05 24.0 1.7 9.2 6.6 0.0 6.1 4 2 3 7 7 7 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC31771.1 - 0.00053 20.7 1.2 3.5 8.7 0.0 5.3 5 0 0 5 5 5 2 WD domain, G-beta repeat FLYWCH PF04500.16 EGC31771.1 - 0.055 13.6 0.2 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 FLYWCH zinc finger domain ABC2_membrane_3 PF12698.7 EGC31772.1 - 9.3e-31 107.2 22.1 1.4e-30 106.6 22.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGC31772.1 - 1.2e-28 100.3 0.0 2.4e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.24 EGC31772.1 - 8.6e-23 80.9 14.3 8.6e-23 80.9 14.3 2.7 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.6 EGC31772.1 - 1.8e-12 47.7 0.1 1.1e-07 32.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC31772.1 - 0.00041 20.8 0.0 0.00082 19.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGC31772.1 - 0.00089 19.0 0.1 0.002 17.8 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGC31772.1 - 0.0014 18.1 1.6 0.4 10.1 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.17 EGC31772.1 - 0.0031 17.6 0.5 0.0081 16.3 0.5 1.6 1 0 0 1 1 1 1 Helicase HerA, central domain RsgA_GTPase PF03193.16 EGC31772.1 - 0.0066 16.4 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_22 PF13401.6 EGC31772.1 - 0.013 15.8 0.3 0.048 13.9 0.1 1.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.9 EGC31772.1 - 0.016 14.1 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain AAA_24 PF13479.6 EGC31772.1 - 0.02 14.6 0.6 0.036 13.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.14 EGC31772.1 - 0.037 13.9 0.0 0.07 13.0 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.6 EGC31772.1 - 0.051 13.2 0.1 0.27 10.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGC31772.1 - 0.075 13.5 1.9 0.085 13.3 0.3 1.9 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC31772.1 - 0.088 12.5 0.0 0.15 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.6 EGC31772.1 - 0.14 12.5 0.1 0.3 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGC31772.1 - 0.15 12.2 0.1 0.31 11.2 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC31772.1 - 0.24 11.6 0.1 0.39 10.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 EGC31772.1 - 0.32 10.2 12.3 0.56 9.4 12.0 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein AAA_15 PF13175.6 EGC31772.1 - 1.7 8.3 10.5 0.42 10.3 0.4 2.8 4 0 0 4 4 4 0 AAA ATPase domain GST_C_3 PF14497.6 EGC31773.1 - 1.5e-10 41.2 0.7 1.5e-10 41.2 0.7 1.5 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC31773.1 - 7.1e-08 32.7 0.4 1.9e-07 31.3 0.1 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC31773.1 - 8.4e-07 29.1 0.4 2.8e-06 27.5 0.2 2.0 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC31773.1 - 0.0017 18.8 0.0 0.0034 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC31773.1 - 0.016 15.2 0.0 0.044 13.8 0.0 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC31773.1 - 0.097 12.5 0.4 0.31 10.9 0.4 1.9 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Dickkopf_N PF04706.12 EGC31774.1 - 2.3e-10 40.8 6.4 2.3e-10 40.8 6.4 7.4 5 2 3 8 8 8 1 Dickkopf N-terminal cysteine-rich region Endomucin PF07010.12 EGC31774.1 - 0.37 10.7 2.9 1.1 9.1 2.9 1.9 1 1 0 1 1 1 0 Endomucin Act-Frag_cataly PF09192.10 EGC31775.1 - 4.8e-82 275.5 18.2 6.3e-82 275.1 18.2 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic DUF1717 PF05414.11 EGC31775.1 - 0.058 13.8 0.4 0.17 12.4 0.4 1.8 1 0 0 1 1 1 0 Viral domain of unknown function (DUF1717) Transposase_1 PF01359.18 EGC31775.1 - 0.069 13.0 0.1 0.24 11.3 0.0 1.9 2 0 0 2 2 2 0 Transposase (partial DDE domain) Coilin_N PF15862.5 EGC31776.1 - 0.22 11.3 2.9 14 5.5 2.5 2.3 2 0 0 2 2 2 0 Coilin N-terminus MMR_HSR1 PF01926.23 EGC31777.1 - 2e-05 24.7 0.3 0.012 15.7 0.3 3.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGC31777.1 - 0.0045 16.4 1.1 0.46 9.8 0.0 2.9 3 0 0 3 3 3 2 AIG1 family T2SSE PF00437.20 EGC31777.1 - 0.0089 15.1 0.0 0.019 14.0 0.0 1.5 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGC31777.1 - 0.018 14.8 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_18 PF13238.6 EGC31777.1 - 0.043 14.4 0.5 0.42 11.2 0.0 2.8 3 1 1 4 4 4 0 AAA domain Vir_act_alpha_C PF10400.9 EGC31777.1 - 0.12 13.1 0.9 11 6.8 0.1 2.8 2 0 0 2 2 2 0 Virulence activator alpha C-term AAA_5 PF07728.14 EGC31777.1 - 0.13 12.3 0.0 0.35 10.9 0.0 1.8 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EGC31777.1 - 0.25 11.9 0.0 0.25 11.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter Cgr1 PF03879.14 EGC31778.1 - 3.7e-14 53.0 18.1 3.7e-14 53.0 18.1 2.1 2 0 0 2 2 2 1 Cgr1 family Pro_isomerase PF00160.21 EGC31779.1 - 1.4e-53 181.4 0.0 1.7e-53 181.1 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCH PF00443.29 EGC31780.1 - 9.1e-26 90.9 102.1 9.1e-26 90.9 102.1 5.1 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGC31780.1 - 2.4e-13 50.2 13.2 2.4e-13 50.2 13.2 2.3 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Ras PF00071.22 EGC31782.1 - 8.3e-57 191.3 0.1 9.8e-57 191.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31782.1 - 6.9e-31 107.0 0.0 1.1e-30 106.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31782.1 - 2.9e-11 43.2 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC31782.1 - 5.8e-07 29.6 0.0 4.7e-06 26.7 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC31782.1 - 0.0005 19.7 0.1 0.00093 18.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGC31782.1 - 0.0034 16.9 0.0 0.042 13.4 0.0 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B Gtr1_RagA PF04670.12 EGC31782.1 - 0.0038 16.6 0.2 0.0055 16.1 0.2 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_14 PF13173.6 EGC31782.1 - 0.0041 17.1 0.0 0.063 13.3 0.0 2.1 1 1 1 2 2 2 1 AAA domain RasGEF PF00617.19 EGC31783.1 - 2.6e-49 167.8 0.5 2.6e-49 167.8 0.5 2.9 2 1 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC31783.1 - 3.3e-22 78.7 4.8 3.3e-22 78.7 4.8 4.4 3 1 0 3 3 3 2 RasGEF N-terminal motif Ribosomal_L19e PF01280.20 EGC31784.1 - 8.6e-13 48.6 0.0 1.1e-12 48.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e DEAD PF00270.29 EGC31785.1 - 1.6e-44 151.8 2.2 1.6e-44 151.8 2.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC31785.1 - 4.7e-32 110.6 1.8 5.2e-31 107.3 0.2 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC31785.1 - 0.00011 22.2 0.3 0.00051 20.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGC31785.1 - 0.00023 21.5 0.5 0.0057 17.0 0.3 2.2 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGC31785.1 - 0.0015 18.3 0.5 0.0031 17.3 0.2 1.7 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 EGC31785.1 - 0.0056 16.1 0.3 0.014 14.8 0.0 1.8 2 1 0 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit tRNA-synt_1b PF00579.25 EGC31785.1 - 0.0068 15.8 0.0 0.017 14.4 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) TniB PF05621.11 EGC31785.1 - 0.024 14.0 0.2 0.055 12.9 0.1 1.6 2 0 0 2 2 2 0 Bacterial TniB protein Helicase_RecD PF05127.14 EGC31785.1 - 0.045 13.6 0.6 0.073 12.9 0.1 1.7 2 0 0 2 2 2 0 Helicase Herpes_UL92 PF03048.14 EGC31785.1 - 0.098 12.4 1.7 0.18 11.6 1.7 1.4 1 0 0 1 1 1 0 UL92 family AAA_22 PF13401.6 EGC31785.1 - 0.099 12.9 1.6 0.66 10.2 1.6 2.1 1 1 0 1 1 1 0 AAA domain NYN PF01936.18 EGC31786.1 - 3.9e-22 79.3 0.1 3.9e-22 79.3 0.1 2.9 3 1 0 3 3 3 1 NYN domain AMPK1_CBM PF16561.5 EGC31786.1 - 1.8e-21 76.1 0.0 1e-12 48.0 0.0 4.3 2 0 0 2 2 2 2 Glycogen recognition site of AMP-activated protein kinase OHA PF14418.6 EGC31786.1 - 5.6e-21 74.1 0.9 1e-19 70.1 0.0 3.7 3 0 0 3 3 3 1 OST-HTH Associated domain Coilin_N PF15862.5 EGC31786.1 - 1.8 8.3 0.0 1.8 8.3 0.0 6.8 3 2 2 5 5 5 0 Coilin N-terminus Cytomega_UL84 PF06284.11 EGC31786.1 - 8.6 4.7 12.8 16 3.8 12.8 1.3 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein MINDY_DUB PF04424.13 EGC31787.1 - 3.6e-27 94.7 0.1 6.6e-27 93.9 0.1 1.5 1 0 0 1 1 1 1 MINDY deubiquitinase DUF423 PF04241.15 EGC31788.1 - 1.2e-23 83.1 0.0 1.6e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ribosomal_S18 PF01084.20 EGC31789.1 - 1e-09 38.5 0.1 8.4e-09 35.5 0.0 2.7 3 0 0 3 3 3 1 Ribosomal protein S18 TT_ORF2 PF02957.15 EGC31789.1 - 0.57 11.1 4.3 0.48 11.4 0.5 2.7 2 0 0 2 2 2 0 TT viral ORF2 RPAP1_N PF08621.10 EGC31789.1 - 7.3 6.5 17.1 2.8 7.8 0.4 4.6 4 0 0 4 4 4 0 RPAP1-like, N-terminal UCH PF00443.29 EGC31790.1 - 4e-51 174.0 2.6 4.7e-51 173.7 2.6 1.0 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC31790.1 - 2.7e-20 73.2 3.6 3.8e-20 72.7 3.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.6 EGC31790.1 - 2.4 7.6 8.3 2.2 7.7 0.2 3.1 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase DUF3915 PF13054.6 EGC31791.1 - 0.012 15.6 2.5 0.064 13.2 2.5 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) BRCT PF00533.26 EGC31791.1 - 0.047 14.1 0.1 0.047 14.1 0.1 3.3 4 1 0 4 4 4 0 BRCA1 C Terminus (BRCT) domain Aha1_N PF09229.11 EGC31792.1 - 3.3e-32 111.5 0.1 5.8e-32 110.8 0.1 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.11 EGC31792.1 - 1.1e-14 54.7 0.0 2e-14 53.9 0.0 1.4 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Exo84_C PF16528.5 EGC31792.1 - 0.28 11.0 1.4 0.31 10.8 0.4 1.5 2 0 0 2 2 2 0 Exocyst component 84 C-terminal Trp_dioxygenase PF03301.13 EGC31793.1 - 2.1e-119 398.9 3.5 2.6e-119 398.6 3.5 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Rubis-subs-bind PF09273.11 EGC31794.1 - 2.2e-21 76.9 0.0 4e-21 76.1 0.0 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGC31794.1 - 2.7e-12 47.4 0.2 1.1e-11 45.4 0.0 2.2 2 0 0 2 2 2 1 SET domain Ubiquitin_2 PF14560.6 EGC31794.1 - 0.085 13.3 2.0 0.21 12.1 2.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Sulfotransfer_2 PF03567.14 EGC31795.1 - 6.5e-13 49.2 0.5 6.5e-13 49.2 0.5 2.1 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGC31795.1 - 5e-06 25.7 0.8 1.9e-05 23.8 0.3 2.3 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase SurA_N_2 PF13623.6 EGC31795.1 - 0.0014 18.6 10.4 0.0033 17.3 10.4 1.6 1 0 0 1 1 1 1 SurA N-terminal domain Sulfotransfer_1 PF00685.27 EGC31795.1 - 0.012 15.1 0.1 0.012 15.1 0.1 2.2 2 0 0 2 2 2 0 Sulfotransferase domain ODV-E18 PF10717.9 EGC31795.1 - 0.014 15.2 3.1 0.024 14.5 3.1 1.3 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 DUF2254 PF10011.9 EGC31795.1 - 0.021 13.7 1.4 0.031 13.1 1.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) Spt20 PF12090.8 EGC31795.1 - 0.025 14.2 15.7 0.049 13.2 15.7 1.4 1 0 0 1 1 1 0 Spt20 family O-antigen_lig PF13425.6 EGC31795.1 - 0.034 13.0 9.0 0.056 12.2 9.0 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Spore_coat_CotO PF14153.6 EGC31795.1 - 0.074 13.0 17.9 0.13 12.2 17.9 1.3 1 0 0 1 1 1 0 Spore coat protein CotO DUF1980 PF09323.10 EGC31795.1 - 0.087 12.7 4.1 0.16 11.9 4.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Sulfotransfer_3 PF13469.6 EGC31795.1 - 0.098 13.0 3.0 0.42 10.9 0.1 2.3 2 0 0 2 2 2 0 Sulfotransferase family DUF2547 PF10818.8 EGC31795.1 - 0.13 13.2 11.4 0.28 12.1 11.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) YABBY PF04690.13 EGC31795.1 - 0.13 12.8 4.5 0.24 11.9 4.5 1.4 1 0 0 1 1 1 0 YABBY protein Plant_vir_prot PF01307.17 EGC31795.1 - 0.18 12.0 0.7 0.32 11.2 0.7 1.3 1 0 0 1 1 1 0 Plant viral movement protein Peptidase_S49_N PF08496.10 EGC31795.1 - 0.22 11.5 9.2 0.45 10.6 9.2 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.6 EGC31795.1 - 0.23 9.9 6.1 0.3 9.5 6.1 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Auxin_canalis PF05703.11 EGC31795.1 - 0.25 11.2 2.3 0.37 10.7 2.3 1.2 1 0 0 1 1 1 0 Auxin canalisation DUF2570 PF10828.8 EGC31795.1 - 0.31 10.9 13.9 1 9.2 13.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF3987 PF13148.6 EGC31795.1 - 0.32 9.9 3.1 0.62 9.0 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) EMC3_TMCO1 PF01956.16 EGC31795.1 - 0.4 10.4 6.9 0.7 9.6 6.9 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like LCIB_C_CA PF18599.1 EGC31795.1 - 0.51 9.6 3.3 0.94 8.7 3.3 1.5 1 0 0 1 1 1 0 Limiting CO2-inducible proteins B/C beta carbonyic anhydrases DUF4407 PF14362.6 EGC31795.1 - 0.54 9.6 4.9 0.79 9.0 4.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.15 EGC31795.1 - 0.56 9.1 5.3 0.81 8.5 5.3 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Zip PF02535.22 EGC31795.1 - 0.61 9.2 2.0 0.94 8.6 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2149 PF09919.9 EGC31795.1 - 0.67 10.2 3.6 1.7 8.9 3.6 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) SNF5 PF04855.12 EGC31795.1 - 0.72 9.6 11.3 1.3 8.8 11.3 1.4 1 0 0 1 1 1 0 SNF5 / SMARCB1 / INI1 DUF4446 PF14584.6 EGC31795.1 - 0.81 9.7 6.9 2.2 8.2 6.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.16 EGC31795.1 - 0.97 9.4 5.4 1.6 8.7 5.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 EGC31795.1 - 1.5 6.6 9.9 2 6.3 9.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gastrin PF00918.17 EGC31795.1 - 2 9.4 9.1 6 7.9 7.2 2.4 2 1 0 2 2 2 0 Gastrin/cholecystokinin family DUF3523 PF12037.8 EGC31795.1 - 2 7.7 18.9 3.2 7.1 18.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3523) CSG2 PF16965.5 EGC31795.1 - 2.1 7.2 5.4 3.4 6.5 5.4 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Ebp2 PF05890.12 EGC31795.1 - 5 6.6 19.3 7.9 6.0 19.3 1.3 1 0 0 1 1 1 0 Eukaryotic rRNA processing protein EBP2 DUF4834 PF16118.5 EGC31795.1 - 7.5 7.6 13.4 23 6.0 13.4 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) ICA69 PF04629.14 EGC31795.1 - 9.6 6.4 13.2 16 5.7 13.2 1.3 1 0 0 1 1 1 0 Islet cell autoantigen ICA69, C-terminal domain UCH PF00443.29 EGC31796.1 - 2.8e-52 177.8 1.7 2.8e-52 177.8 1.7 2.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC31796.1 - 6.9e-19 68.6 2.3 6.9e-19 68.6 2.3 2.4 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUF4834 PF16118.5 EGC31796.1 - 0.013 16.4 2.7 0.05 14.6 2.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EGF_2 PF07974.13 EGC31797.1 - 3.2e-54 181.0 305.8 0.00014 22.2 13.0 15.8 15 0 0 15 15 15 14 EGF-like domain EGF_Tenascin PF18720.1 EGC31797.1 - 1.6e-21 75.9 237.2 0.011 15.8 7.5 15.8 15 0 0 15 15 15 13 Tenascin EGF domain Laminin_EGF PF00053.24 EGC31797.1 - 0.0044 17.1 276.4 0.58 10.4 9.0 15.6 14 1 1 15 15 15 14 Laminin EGF domain ADH_N PF08240.12 EGC31798.1 - 8.8e-26 89.9 4.5 8.8e-26 89.9 4.5 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC31798.1 - 4.4e-18 65.5 0.0 7.5e-18 64.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC31798.1 - 0.00071 20.6 0.0 0.0011 20.0 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EGC31798.1 - 0.058 13.1 0.2 0.095 12.4 0.2 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EGC31798.1 - 0.079 12.3 0.1 0.12 11.8 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain CoA_binding PF02629.19 EGC31798.1 - 0.14 12.9 0.2 0.44 11.3 0.1 1.8 2 0 0 2 2 2 0 CoA binding domain ADH_zinc_N PF00107.26 EGC31799.1 - 5.4e-18 65.2 0.0 1.3e-17 64.0 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC31799.1 - 1.5e-17 63.4 2.4 3e-17 62.5 2.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGC31799.1 - 0.00048 21.2 0.0 0.0007 20.7 0.0 1.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGC31799.1 - 0.018 14.4 0.1 0.028 13.8 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.21 EGC31799.1 - 0.033 13.9 0.1 0.049 13.3 0.1 1.3 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase AAA_assoc_2 PF16193.5 EGC31799.1 - 0.12 12.7 0.0 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 AAA C-terminal domain DUF3430 PF11912.8 EGC31800.1 - 3.1e-24 86.2 45.6 5.8e-24 85.3 45.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) PAF-AH_p_II PF03403.13 EGC31802.1 - 0.01 14.4 0.4 0.018 13.6 0.4 1.3 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II GDPD PF03009.17 EGC31803.1 - 7.9e-49 166.7 0.2 1.3e-47 162.8 0.1 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.19 EGC31803.1 - 6.7e-17 61.2 0.7 6.7e-17 61.2 0.7 2.6 3 0 0 3 3 3 1 Starch binding domain Methyltransf_7 PF03492.15 EGC31804.1 - 1.5e-30 106.6 9.0 2e-30 106.2 9.0 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase OPT PF03169.15 EGC31804.1 - 0.72 8.4 1.9 6 5.4 0.0 2.0 2 0 0 2 2 2 0 OPT oligopeptide transporter protein TIG PF01833.24 EGC31805.1 - 4.4e-09 36.3 11.2 0.0003 20.8 0.6 3.4 2 0 0 2 2 2 2 IPT/TIG domain LRR_8 PF13855.6 EGC31805.1 - 1.6e-05 24.6 12.7 0.00034 20.3 1.7 3.4 2 1 1 3 3 3 2 Leucine rich repeat EGF_2 PF07974.13 EGC31805.1 - 0.00059 20.1 65.3 0.012 16.0 6.6 4.8 4 0 0 4 4 4 3 EGF-like domain EB PF01683.18 EGC31805.1 - 0.0049 17.1 2.9 0.0049 17.1 2.9 5.0 5 1 1 6 6 6 1 EB module LRR_4 PF12799.7 EGC31805.1 - 0.0056 17.1 1.3 0.0056 17.1 1.3 4.8 3 1 3 6 6 6 3 Leucine Rich repeats (2 copies) TRM13 PF05206.14 EGC31805.1 - 0.045 13.3 0.1 0.076 12.5 0.1 1.2 1 0 0 1 1 1 0 Methyltransferase TRM13 LRR_1 PF00560.33 EGC31805.1 - 0.054 14.1 14.0 0.091 13.4 0.2 6.2 3 2 1 4 4 4 0 Leucine Rich Repeat DUF4369 PF14289.6 EGC31805.1 - 0.091 13.3 3.2 0.19 12.3 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4369) LRR_6 PF13516.6 EGC31805.1 - 0.44 10.7 3.8 4.5 7.6 0.1 4.2 4 0 0 4 4 4 0 Leucine Rich repeat EGF_Tenascin PF18720.1 EGC31805.1 - 5.1 7.2 39.1 0.021 14.9 9.0 4.6 4 0 0 4 4 4 0 Tenascin EGF domain Acetyltransf_5 PF13444.6 EGC31806.1 - 3.1e-06 27.8 0.2 0.0011 19.6 0.1 3.3 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC31806.1 - 0.23 11.7 1.1 0.42 10.9 1.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family YqzE PF14038.6 EGC31807.1 - 0.042 13.8 0.1 0.075 13.0 0.1 1.4 1 0 0 1 1 1 0 YqzE-like protein ADH_N PF08240.12 EGC31808.1 - 3.4e-26 91.2 3.9 6.6e-26 90.3 3.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC31808.1 - 2e-16 60.1 0.6 3.5e-16 59.4 0.1 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC31808.1 - 0.0024 18.9 0.0 0.0036 18.3 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.21 EGC31808.1 - 0.028 14.2 0.4 0.04 13.6 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase CoA_binding PF02629.19 EGC31808.1 - 0.046 14.4 0.3 0.17 12.6 0.1 1.9 2 0 0 2 2 2 0 CoA binding domain 2-Hacid_dh_C PF02826.19 EGC31808.1 - 0.1 12.0 0.2 0.15 11.4 0.2 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_N PF08240.12 EGC31809.1 - 2.5e-21 75.6 8.3 5.3e-21 74.5 8.3 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC31809.1 - 3.6e-17 62.6 0.3 1.1e-16 61.0 0.1 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC31809.1 - 5.7e-05 24.2 0.0 9e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PEARLI-4 PF05278.12 EGC31810.1 - 0.008 15.8 2.9 0.008 15.8 2.9 1.7 2 0 0 2 2 2 1 Arabidopsis phospholipase-like protein (PEARLI 4) DUF327 PF03885.13 EGC31810.1 - 0.11 12.5 9.7 0.79 9.7 0.3 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF327) Ribosomal_S6 PF01250.17 EGC31810.1 - 0.17 12.2 1.3 0.28 11.5 0.2 1.9 2 0 0 2 2 2 0 Ribosomal protein S6 DUF5043 PF16446.5 EGC31810.1 - 0.18 11.8 1.2 0.7 9.9 0.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5043) TssO PF17561.2 EGC31810.1 - 0.58 10.3 8.2 0.47 10.6 0.4 2.6 2 1 0 2 2 2 0 Type VI secretion system, TssO CCDC-167 PF15188.6 EGC31810.1 - 1.3 9.4 13.0 0.17 12.2 5.4 2.6 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Laminin_II PF06009.12 EGC31810.1 - 8.8 6.3 13.6 1.8 8.6 6.6 2.3 1 1 1 2 2 2 0 Laminin Domain II HSP90 PF00183.18 EGC31811.1 - 9.6e-225 747.3 36.7 1.3e-224 746.9 36.7 1.1 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGC31811.1 - 1.5e-15 57.6 0.2 3.4e-15 56.5 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGC31811.1 - 2.9e-08 33.6 0.4 2.9e-08 33.6 0.4 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DUF4140 PF13600.6 EGC31811.1 - 4.2 7.9 8.3 7.3 7.1 0.2 2.6 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) VASt PF16016.5 EGC31812.1 - 4.5e-35 121.3 2.4 1.2e-34 119.9 2.4 1.8 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain GRAM PF02893.20 EGC31812.1 - 6e-21 74.5 0.5 3e-20 72.2 0.5 2.2 1 0 0 1 1 1 1 GRAM domain His_Phos_1 PF00300.22 EGC31813.1 - 2.5e-26 92.6 0.0 3.5e-26 92.1 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Adaptin_binding PF10199.9 EGC31814.1 - 4.2 8.0 10.7 10 6.7 10.7 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Vip3A_N PF12495.8 EGC31815.1 - 0.015 15.2 0.0 0.019 14.9 0.0 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal EF-hand_7 PF13499.6 EGC31815.1 - 0.053 14.0 1.6 1.7 9.2 0.5 2.5 2 1 0 2 2 2 0 EF-hand domain pair MFS_1 PF07690.16 EGC31816.1 - 8.7e-21 74.2 32.7 7.2e-11 41.6 10.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGC31816.1 - 6.6e-18 64.5 14.0 6.6e-18 64.5 14.0 2.0 1 1 1 2 2 2 1 MFS/sugar transport protein PUCC PF03209.15 EGC31816.1 - 1.8e-07 30.6 0.0 1.8e-07 30.6 0.0 2.1 2 0 0 2 2 2 1 PUCC protein RCC1 PF00415.18 EGC31817.1 - 2.4e-73 242.6 5.2 3.9e-12 46.6 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC31817.1 - 1.5e-41 139.4 22.8 5.2e-08 32.5 0.2 7.8 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat SDA1 PF05285.12 EGC31818.1 - 0.056 12.9 34.7 0.079 12.4 34.7 1.1 1 0 0 1 1 1 0 SDA1 SR-25 PF10500.9 EGC31818.1 - 0.4 10.2 17.0 0.38 10.3 15.0 1.7 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein BUD22 PF09073.10 EGC31818.1 - 0.7 9.2 29.7 0.88 8.8 29.7 1.1 1 0 0 1 1 1 0 BUD22 PNISR PF15996.5 EGC31818.1 - 0.73 10.1 19.0 1.3 9.3 19.0 1.4 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR Macoilin PF09726.9 EGC31818.1 - 0.8 8.2 17.4 0.88 8.1 17.4 1.1 1 0 0 1 1 1 0 Macoilin family Nop14 PF04147.12 EGC31818.1 - 1.2 7.2 35.3 1.6 6.8 35.3 1.1 1 0 0 1 1 1 0 Nop14-like family Presenilin PF01080.17 EGC31818.1 - 2.6 6.7 18.1 3.5 6.3 18.1 1.2 1 0 0 1 1 1 0 Presenilin SLC12 PF03522.15 EGC31818.1 - 3.6 6.5 18.6 5.1 6.0 18.6 1.3 1 0 0 1 1 1 0 Solute carrier family 12 Raftlin PF15250.6 EGC31818.1 - 6.7 5.3 12.7 8.7 5.0 12.7 1.1 1 0 0 1 1 1 0 Raftlin Hid1 PF12722.7 EGC31818.1 - 8.9 4.3 14.7 10 4.1 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Pet191_N PF10203.9 EGC31819.1 - 0.0089 16.3 1.5 0.015 15.6 1.5 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 Gram_pos_anchor PF00746.21 EGC31820.1 - 0.02 14.8 0.1 0.64 10.0 0.0 2.4 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DUF3800 PF12686.7 EGC31820.1 - 8.2 7.1 9.1 1.7 9.3 5.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) Aminotran_1_2 PF00155.21 EGC31821.1 - 3.1e-49 168.1 0.0 3.7e-49 167.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGC31821.1 - 0.077 11.5 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme FYVE PF01363.21 EGC31822.1 - 3e-18 65.7 12.0 7.2e-18 64.5 12.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.23 EGC31822.1 - 4.2e-12 45.7 1.3 0.001 19.0 0.0 6.2 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat STAG PF08514.11 EGC31822.1 - 0.024 14.5 0.0 0.088 12.7 0.0 1.9 1 0 0 1 1 1 0 STAG domain Aldo_ket_red PF00248.21 EGC31823.1 - 6.2e-55 186.5 0.0 7.7e-54 182.9 0.0 1.9 1 1 0 1 1 1 1 Aldo/keto reductase family CH PF00307.31 EGC31824.1 - 4.4e-16 59.0 0.0 4.4e-16 59.0 0.0 3.5 3 1 0 3 3 3 1 Calponin homology (CH) domain SBF2 PF12335.8 EGC31824.1 - 5.4e-07 29.5 0.1 5.4e-07 29.5 0.1 3.4 4 0 0 4 4 4 1 Myotubularin protein Med21 PF11221.8 EGC31824.1 - 0.00061 20.1 6.8 0.00061 20.1 6.8 4.6 5 1 0 5 5 5 1 Subunit 21 of Mediator complex CDC24 PF06395.11 EGC31824.1 - 0.014 15.6 1.5 0.13 12.5 0.0 3.3 3 0 0 3 3 3 0 CDC24 Calponin CAMSAP_CH PF11971.8 EGC31824.1 - 0.015 15.1 0.5 0.051 13.4 0.0 2.2 2 0 0 2 2 2 0 CAMSAP CH domain CENP-Q PF13094.6 EGC31824.1 - 0.053 13.7 27.9 0.049 13.8 6.1 3.0 2 1 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit NOB1_Zn_bind PF08772.11 EGC31824.1 - 6.9 6.9 9.1 1.7 8.9 2.8 3.0 2 0 0 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Aph-1 PF06105.12 EGC31825.1 - 7.6e-92 306.9 2.9 9e-92 306.6 2.9 1.0 1 0 0 1 1 1 1 Aph-1 protein CNDH2_C PF16858.5 EGC31825.1 - 0.0036 17.2 5.3 0.0049 16.8 5.3 1.1 1 0 0 1 1 1 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term PsaL PF02605.15 EGC31825.1 - 0.0067 16.1 3.1 0.82 9.3 0.6 2.4 1 1 1 2 2 2 2 Photosystem I reaction centre subunit XI V_ATPase_I PF01496.19 EGC31825.1 - 1 7.2 7.6 1.5 6.6 7.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BPL_N PF09825.9 EGC31825.1 - 2.2 7.3 5.0 2.9 6.9 5.0 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal RasGEF PF00617.19 EGC31826.1 - 2.8e-57 193.8 1.8 2.8e-57 193.8 1.8 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC31826.1 - 2.7e-20 72.6 0.8 2.7e-20 72.6 0.8 3.8 3 0 0 3 3 3 1 RasGEF N-terminal motif NCA2 PF08637.10 EGC31827.1 - 1.4e-55 188.5 7.5 1.4e-55 188.5 7.5 3.2 3 1 0 3 3 3 1 ATP synthase regulation protein NCA2 SR-25 PF10500.9 EGC31827.1 - 4.6 6.8 20.8 14 5.2 20.8 1.7 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIT PF04212.18 EGC31828.1 - 2e-24 85.4 6.8 1.3e-14 54.0 1.0 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.22 EGC31828.1 - 9e-08 32.2 0.5 2.1e-05 24.6 0.2 2.4 1 1 1 2 2 2 2 LIM domain Arrestin_C PF02752.22 EGC31828.1 - 4.1e-06 27.3 0.1 4.1e-06 27.3 0.1 2.8 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain SUIM_assoc PF16619.5 EGC31828.1 - 0.0077 16.3 6.0 0.0077 16.3 6.0 3.1 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 MG2 PF01835.19 EGC31828.1 - 0.051 14.0 0.8 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 MG2 domain zf-RING-like PF08746.11 EGC31828.1 - 0.26 11.6 1.5 2.4 8.6 1.0 2.3 1 1 1 2 2 2 0 RING-like domain Nop53 PF07767.11 EGC31829.1 - 2.8e-29 102.7 47.4 9.9e-27 94.3 46.5 2.5 1 1 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) Peptidase_A3 PF02160.15 EGC31829.1 - 1.2 8.5 17.4 0.061 12.8 6.3 2.4 2 0 0 2 2 2 0 Cauliflower mosaic virus peptidase (A3) SbsC_C PF18058.1 EGC31829.1 - 3.7 7.8 18.7 0.17 12.1 6.6 2.8 2 0 0 2 2 2 0 SbsC C-terminal domain zf-CCHC PF00098.23 EGC31831.1 - 8.5e-06 25.6 1.1 1.8e-05 24.6 1.1 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGC31831.1 - 0.003 17.3 0.2 0.0051 16.6 0.2 1.4 1 0 0 1 1 1 1 Zinc knuckle DUF1825 PF08855.10 EGC31831.1 - 0.021 14.7 0.1 0.055 13.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1825) UBA_3 PF09288.10 EGC31832.1 - 0.2 11.5 2.1 2.2 8.1 0.1 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain EMP70 PF02990.16 EGC31833.1 - 0.04 12.6 10.6 0.053 12.2 10.6 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DUF2070 PF09843.9 EGC31833.1 - 4 5.6 12.1 5 5.3 12.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) TMEM190 PF15431.6 EGC31833.1 - 4.1 7.6 9.2 2 8.6 4.4 2.4 2 1 0 2 2 2 0 Transmembrane protein 190 DUF3430 PF11912.8 EGC31834.1 - 1.3e-06 28.6 28.3 1.6e-06 28.3 28.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC31834.1 - 3.3 8.0 11.4 1.8 8.9 0.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF3586) DUF2569 PF10754.9 EGC31835.1 - 4.9 7.6 11.0 12 6.3 0.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) MFS_1 PF07690.16 EGC31836.1 - 7.4e-22 77.7 31.8 7.4e-22 77.7 31.8 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.6 EGC31836.1 - 6.5e-07 28.2 29.4 3.2e-05 22.7 5.0 2.5 2 1 1 3 3 3 2 MFS/sugar transport protein Bac_export_2 PF01312.19 EGC31836.1 - 0.003 16.8 4.0 0.003 16.8 4.0 1.7 1 1 0 1 1 1 1 FlhB HrpN YscU SpaS Family TMCO5 PF14992.6 EGC31836.1 - 0.13 11.9 0.1 0.27 10.8 0.1 1.5 1 0 0 1 1 1 0 TMCO5 family HATPase_c_3 PF13589.6 EGC31837.1 - 5.2e-17 62.0 0.4 5.2e-17 62.0 0.4 2.3 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGC31837.1 - 2.8e-05 24.6 0.1 0.00011 22.7 0.1 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pox_RNA_Pol_19 PF05320.12 EGC31837.1 - 0.00068 19.7 1.6 0.00068 19.7 1.6 4.0 5 0 0 5 5 5 1 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Chorein_N PF12624.7 EGC31837.1 - 0.26 11.4 5.9 13 5.9 0.0 4.4 2 1 1 3 3 3 0 N-terminal region of Chorein or VPS13 SDA1 PF05285.12 EGC31837.1 - 2.4 7.5 42.9 1.2 8.5 2.7 3.5 3 0 0 3 3 3 0 SDA1 EBV-NA3 PF05009.12 EGC31837.1 - 7.9 5.9 10.9 0.41 10.1 2.6 2.2 2 0 0 2 2 2 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CAP PF00188.26 EGC31838.1 - 0.05 14.4 2.2 0.21 12.4 0.2 2.3 2 0 0 2 2 2 0 Cysteine-rich secretory protein family Profilin PF00235.19 EGC31838.1 - 0.055 13.7 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 Profilin IPT PF01745.16 EGC31839.1 - 9.4e-33 113.5 0.1 2.5e-31 108.9 0.1 2.1 1 1 0 1 1 1 1 Isopentenyl transferase IPPT PF01715.17 EGC31839.1 - 0.00046 20.1 0.1 0.011 15.5 0.3 2.1 1 1 1 2 2 2 1 IPP transferase AAA_22 PF13401.6 EGC31839.1 - 0.00063 20.0 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain EndoU_bacteria PF14436.6 EGC31839.1 - 0.0064 16.8 0.0 0.011 16.1 0.0 1.5 1 1 0 1 1 1 1 Bacterial EndoU nuclease ATP-cone PF03477.16 EGC31839.1 - 0.016 15.7 2.2 0.36 11.4 0.2 2.8 2 1 2 4 4 4 0 ATP cone domain AAA_18 PF13238.6 EGC31839.1 - 0.084 13.4 0.1 0.25 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain RED_N PF07808.13 EGC31839.1 - 0.11 12.0 2.7 0.055 13.1 0.7 1.6 2 0 0 2 2 2 0 RED-like protein N-terminal region AAA_33 PF13671.6 EGC31839.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain RRM_1 PF00076.22 EGC31840.1 - 0.00052 19.8 0.2 0.0023 17.7 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH_4 PF18044.1 EGC31840.1 - 0.00057 19.6 1.7 0.0012 18.6 1.7 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-CCCH PF00642.24 EGC31840.1 - 0.00097 19.0 2.1 0.0024 17.7 2.1 1.7 1 1 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGC31840.1 - 1.9 8.6 5.3 0.39 10.9 0.6 2.2 2 0 0 2 2 2 0 Zinc finger domain DUF747 PF05346.11 EGC31841.1 - 1.6e-102 343.3 19.2 2.4e-102 342.7 19.2 1.3 1 0 0 1 1 1 1 Eukaryotic membrane protein family ATG_C PF09333.11 EGC31842.1 - 2e-16 60.1 0.2 2.3e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 Autophagy-related protein C terminal domain VPS13_C PF16909.5 EGC31842.1 - 8.3e-06 25.7 6.7 0.015 15.1 0.5 2.6 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal zf-B_box PF00643.24 EGC31842.1 - 0.00028 21.0 9.5 0.00044 20.3 9.5 1.3 1 0 0 1 1 1 1 B-box zinc finger Mito_carr PF00153.27 EGC31842.1 - 0.052 13.5 0.5 4.3 7.3 0.0 2.7 2 0 0 2 2 2 0 Mitochondrial carrier protein AAA_23 PF13476.6 EGC31844.1 - 9.4e-19 68.7 3.8 9.4e-19 68.7 3.8 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.19 EGC31844.1 - 3.9e-15 55.9 1.3 6.3e-15 55.2 1.3 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGC31844.1 - 1.5e-10 41.4 5.5 1.5e-10 41.4 5.5 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGC31844.1 - 0.00037 20.2 0.3 0.00097 18.8 0.1 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain AF-4 PF05110.13 EGC31844.1 - 0.00099 17.3 19.9 0.0013 17.0 19.9 1.1 1 0 0 1 1 1 1 AF-4 proto-oncoprotein MukB PF04310.12 EGC31844.1 - 0.0027 17.5 0.0 0.0045 16.8 0.0 1.3 1 0 0 1 1 1 1 MukB N-terminal Serglycin PF04360.12 EGC31844.1 - 0.0087 16.0 5.6 0.021 14.8 5.6 1.6 1 0 0 1 1 1 1 Serglycin AAA_21 PF13304.6 EGC31844.1 - 0.35 10.6 5.4 0.055 13.3 0.5 2.0 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Cwf_Cwc_15 PF04889.12 EGC31844.1 - 1.7 8.3 18.5 3.3 7.4 18.5 1.4 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DNA_pol_phi PF04931.13 EGC31844.1 - 4.2 5.4 13.9 6.5 4.7 13.9 1.2 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EGC31844.1 - 7.4 4.7 10.6 10 4.3 10.6 1.1 1 0 0 1 1 1 0 CDC45-like protein SMC_N PF02463.19 EGC31845.1 - 2.8e-11 43.3 1.4 4.2e-11 42.7 1.4 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain COG5 PF10392.9 EGC31845.1 - 0.59 10.3 12.1 0.16 12.2 7.3 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF1664 PF07889.12 EGC31845.1 - 3.8 7.6 14.0 1.4 9.0 6.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) HALZ PF02183.18 EGC31846.1 - 8.9e-05 22.6 0.3 0.00018 21.6 0.3 1.6 1 1 0 1 1 1 1 Homeobox associated leucine zipper Cnn_1N PF07989.11 EGC31846.1 - 0.0022 18.1 1.3 0.0032 17.6 1.3 1.5 1 1 0 1 1 1 1 Centrosomin N-terminal motif 1 MbeD_MobD PF04899.12 EGC31846.1 - 0.0035 17.4 0.1 0.0056 16.8 0.1 1.3 1 0 0 1 1 1 1 MbeD/MobD like DivIC PF04977.15 EGC31846.1 - 0.0053 16.5 0.9 0.0087 15.8 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator bZIP_1 PF00170.21 EGC31846.1 - 0.012 15.6 0.3 0.028 14.5 0.3 1.7 1 1 0 1 1 1 0 bZIP transcription factor DUF1640 PF07798.11 EGC31846.1 - 0.04 14.0 0.3 0.056 13.5 0.3 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) Matrilin_ccoil PF10393.9 EGC31846.1 - 0.063 13.2 0.5 0.24 11.3 0.4 1.9 2 0 0 2 2 2 0 Trimeric coiled-coil oligomerisation domain of matrilin FlaC_arch PF05377.11 EGC31846.1 - 0.1 13.0 0.6 0.38 11.2 0.1 2.0 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) ZapB PF06005.12 EGC31846.1 - 0.14 12.6 1.0 0.14 12.6 1.0 1.6 1 1 0 1 1 1 0 Cell division protein ZapB RIC3 PF15361.6 EGC31847.1 - 0.0067 16.8 0.1 0.01 16.2 0.1 1.3 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 FeoB_associated PF12669.7 EGC31847.1 - 0.049 14.0 0.6 0.098 13.1 0.6 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF1461 PF07314.11 EGC31847.1 - 0.064 13.2 3.2 1.1 9.1 0.3 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF1461) Ribosomal_L3 PF00297.22 EGC31848.1 - 4.9e-18 65.3 1.6 6.3e-16 58.3 0.4 2.2 1 1 1 2 2 2 2 Ribosomal protein L3 RRM_1 PF00076.22 EGC31849.1 - 5.5e-45 151.1 2.0 3.9e-16 58.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PhetRS_B1 PF18262.1 EGC31849.1 - 0.0017 18.6 0.0 1.8 8.8 0.0 3.1 3 0 0 3 3 3 2 Phe-tRNA synthetase beta subunit B1 domain RRM_7 PF16367.5 EGC31849.1 - 0.0027 17.8 1.7 8 6.7 0.1 3.8 2 2 0 3 3 3 2 RNA recognition motif RRM_3 PF08777.11 EGC31849.1 - 0.023 14.7 4.2 13 5.9 0.0 3.5 3 1 0 3 3 3 0 RNA binding motif Nup35_RRM PF05172.13 EGC31849.1 - 0.05 13.6 0.1 0.05 13.6 0.1 2.8 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.23 EGC31850.1 - 1e-22 80.3 1.0 2.5e-22 79.1 1.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC31850.1 - 6.8e-10 39.3 4.0 6.2e-06 26.4 0.1 3.0 2 1 1 3 3 3 2 Dynamin family KH_2 PF07650.17 EGC31850.1 - 3.2e-09 36.5 1.1 6.7e-09 35.5 0.1 2.1 2 0 0 2 2 2 1 KH domain FeoB_N PF02421.18 EGC31850.1 - 4.2e-09 36.1 0.8 4.2e-09 36.1 0.8 2.2 1 1 1 2 2 2 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC31850.1 - 1.7e-08 34.6 0.7 0.0011 18.9 0.0 2.6 2 1 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC31850.1 - 4.7e-08 32.8 3.5 0.00021 20.9 3.2 3.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGC31850.1 - 9.8e-07 28.3 0.2 9.8e-07 28.3 0.2 2.3 3 0 0 3 3 3 1 AIG1 family PduV-EutP PF10662.9 EGC31850.1 - 2.2e-06 27.5 1.2 0.14 11.9 0.1 3.3 1 1 1 2 2 2 2 Ethanolamine utilisation - propanediol utilisation MMR_HSR1_Xtn PF16897.5 EGC31850.1 - 0.0018 18.2 0.8 0.0056 16.7 0.8 1.9 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain ABC_tran PF00005.27 EGC31850.1 - 0.0067 16.9 2.8 0.021 15.3 2.8 1.9 1 1 0 1 1 1 1 ABC transporter YgbB PF02542.16 EGC31850.1 - 0.011 16.0 0.0 0.023 15.0 0.0 1.5 1 0 0 1 1 1 0 YgbB family Arf PF00025.21 EGC31850.1 - 0.015 14.8 3.1 1.4 8.4 0.0 2.7 2 1 0 2 2 2 0 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.18 EGC31850.1 - 0.023 14.0 0.1 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_29 PF13555.6 EGC31850.1 - 0.035 13.9 0.0 0.14 12.0 0.0 2.0 2 0 0 2 2 2 0 P-loop containing region of AAA domain cobW PF02492.19 EGC31850.1 - 0.048 13.3 2.9 0.7 9.5 1.1 2.5 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EGC31850.1 - 0.052 13.3 0.9 9.7 5.9 0.4 3.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA PF00004.29 EGC31850.1 - 0.08 13.4 1.7 0.42 11.0 1.7 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GSH_synthase PF03199.15 EGC31850.1 - 0.082 13.4 0.7 0.22 12.0 0.7 1.8 1 0 0 1 1 1 0 Eukaryotic glutathione synthase AAA_28 PF13521.6 EGC31850.1 - 0.12 12.6 0.0 0.27 11.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC31850.1 - 0.16 12.2 0.3 0.47 10.7 0.0 2.0 2 1 0 2 2 2 0 AAA domain RRM_1 PF00076.22 EGC31851.1 - 7.9e-06 25.6 1.2 1.7e-05 24.5 0.2 2.2 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_2 PF07724.14 EGC31852.1 - 3.7e-41 141.1 0.0 1.7e-32 112.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.29 EGC31852.1 - 3.4e-14 53.4 0.1 5.4e-06 26.9 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGC31852.1 - 3.5e-07 30.2 1.7 3.5e-07 30.2 1.7 2.6 2 1 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.14 EGC31852.1 - 7.1e-07 29.3 0.1 2.4e-05 24.4 0.0 2.7 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGC31852.1 - 0.00013 21.4 0.0 0.0018 17.7 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGC31852.1 - 0.00047 20.6 0.1 0.0035 17.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC31852.1 - 0.00074 19.8 0.0 0.0065 16.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGC31852.1 - 0.0014 18.3 0.0 0.068 12.9 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain MCM PF00493.23 EGC31852.1 - 0.0043 16.2 0.0 0.072 12.2 0.0 2.2 2 0 0 2 2 2 1 MCM P-loop domain RuvB_N PF05496.12 EGC31852.1 - 0.0047 16.7 0.0 0.29 10.8 0.0 2.4 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGC31852.1 - 0.0098 16.4 0.0 0.029 14.9 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_8 PF12780.7 EGC31852.1 - 0.02 14.2 0.1 0.28 10.4 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region D4 AAA_28 PF13521.6 EGC31852.1 - 0.027 14.7 0.0 0.09 13.0 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGC31852.1 - 0.032 14.0 0.3 0.13 12.0 0.3 2.0 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGC31852.1 - 0.047 13.6 0.1 0.2 11.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_33 PF13671.6 EGC31852.1 - 0.055 13.6 0.0 0.17 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC31852.1 - 0.057 13.2 0.0 0.14 11.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SRP54 PF00448.22 EGC31852.1 - 0.068 12.8 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.12 EGC31852.1 - 0.069 12.4 0.0 0.16 11.2 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin ABC_tran PF00005.27 EGC31852.1 - 2.5 8.6 4.9 10 6.6 0.0 3.3 4 1 0 4 4 3 0 ABC transporter Membrane_bind PF14564.6 EGC31853.1 - 1.9e-40 137.7 0.0 2.8e-40 137.1 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 EGC31853.1 - 7.3e-34 115.8 0.3 1.2e-33 115.2 0.3 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Crystall PF00030.19 EGC31853.1 - 0.093 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin zf-RING_2 PF13639.6 EGC31854.1 - 1e-07 32.1 13.2 1e-07 32.1 13.2 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC31854.1 - 1.3e-06 28.1 10.6 2.9e-06 27.0 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31854.1 - 2.4e-06 27.3 13.0 5.5e-06 26.1 13.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31854.1 - 2.3e-05 24.2 14.2 6e-05 22.8 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC31854.1 - 4e-05 23.6 7.6 0.00027 20.9 7.8 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC31854.1 - 0.00012 22.3 9.6 0.00038 20.7 9.6 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC31854.1 - 0.0038 17.1 13.3 0.008 16.1 13.3 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC31854.1 - 0.02 14.7 11.3 0.05 13.4 11.3 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain LMBR1 PF04791.16 EGC31854.1 - 0.1 11.5 6.2 0.15 10.9 6.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein YjbH PF06082.11 EGC31854.1 - 0.29 9.9 1.9 0.37 9.5 1.9 1.1 1 0 0 1 1 1 0 Exopolysaccharide biosynthesis protein YbjH zf-C3HC4_4 PF15227.6 EGC31854.1 - 0.84 9.9 16.1 0.54 10.5 13.4 2.3 2 1 0 2 2 1 0 zinc finger of C3HC4-type, RING ATG16 PF08614.11 EGC31854.1 - 0.84 9.8 23.2 11 6.2 23.2 2.2 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DZR PF12773.7 EGC31854.1 - 1.2 9.2 8.5 2.9 8.0 8.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 EGC31854.1 - 6.6 6.6 16.6 0.046 13.5 5.7 2.8 3 0 0 3 3 3 0 RING-like zinc finger Sec20 PF03908.13 EGC31855.1 - 0.013 15.4 2.6 0.1 12.5 1.0 2.7 2 1 0 2 2 2 0 Sec20 UCH PF00443.29 EGC31855.1 - 0.043 13.3 4.8 0.054 13.0 4.8 1.1 1 0 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase Pannexin_like PF12534.8 EGC31855.1 - 0.18 10.9 3.7 0.26 10.3 3.7 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 Sigma70_ner PF04546.13 EGC31855.1 - 0.26 11.2 9.1 0.19 11.6 6.0 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region Spore_II_R PF09551.10 EGC31855.1 - 0.46 10.9 5.8 0.22 12.0 3.4 1.6 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) Pex19 PF04614.12 EGC31855.1 - 7.3 6.3 13.5 0.43 10.3 7.1 1.9 2 0 0 2 2 2 0 Pex19 protein family NIPSNAP PF07978.13 EGC31856.1 - 8.3e-18 64.5 0.0 1.1e-08 35.2 0.0 2.2 2 0 0 2 2 2 2 NIPSNAP Flavi_NS5 PF00972.20 EGC31856.1 - 0.049 11.8 0.0 0.064 11.4 0.0 1.1 1 0 0 1 1 1 0 Flavivirus RNA-directed RNA polymerase FNIP PF05725.12 EGC31857.1 - 3.7e-11 43.0 38.2 3.8e-06 27.0 0.0 9.4 5 3 1 6 6 6 3 FNIP Repeat Formyl_trans_N PF00551.19 EGC31858.1 - 9.3e-50 168.9 0.0 1.1e-49 168.7 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase ORF_2_N PF18492.1 EGC31858.1 - 0.052 13.7 0.0 0.14 12.3 0.0 1.7 2 0 0 2 2 2 0 Open reading frame 2 N-terminal domain RST PF12174.8 EGC31858.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.6 1 0 0 1 1 1 0 RCD1-SRO-TAF4 (RST) plant domain FERM_M PF00373.18 EGC31859.1 - 5.6e-20 71.9 0.2 5.4e-19 68.7 0.0 2.8 2 0 0 2 2 2 1 FERM central domain FERM_N PF09379.10 EGC31859.1 - 2e-07 30.8 0.2 9.9e-07 28.6 0.2 2.3 1 0 0 1 1 1 1 FERM N-terminal domain LRR_1 PF00560.33 EGC31859.1 - 1.3e-05 25.1 6.9 41 5.3 0.0 9.1 9 0 0 9 9 9 0 Leucine Rich Repeat LRR_6 PF13516.6 EGC31859.1 - 2.3e-05 24.1 48.8 0.0071 16.3 0.2 12.0 14 0 0 14 14 14 4 Leucine Rich repeat LRR_4 PF12799.7 EGC31859.1 - 0.0016 18.8 0.1 0.0016 18.8 0.1 9.0 9 1 0 9 9 9 2 Leucine Rich repeats (2 copies) DUF2730 PF10805.8 EGC31859.1 - 0.059 13.5 2.1 0.36 11.0 2.1 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2730) DUF3439 PF11921.8 EGC31859.1 - 0.32 10.9 4.1 0.86 9.6 4.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HAP2-GCS1 PF10699.9 EGC31861.1 - 4.5e-18 65.0 0.3 1e-17 63.8 0.3 1.6 1 0 0 1 1 1 1 Male gamete fusion factor MAP17 PF15807.5 EGC31861.1 - 1.8 8.8 8.4 0.095 12.9 2.0 1.9 1 1 1 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 PAT1 PF09770.9 EGC31862.1 - 0.13 10.5 23.4 0.15 10.3 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLDc_N PF13396.6 EGC31862.1 - 0.85 9.6 3.8 1.2 9.1 3.8 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal AAA_23 PF13476.6 EGC31862.1 - 1.5 9.3 19.5 2.1 8.8 19.5 1.3 1 0 0 1 1 1 0 AAA domain FeoB_associated PF12669.7 EGC31862.1 - 1.8 9.0 8.6 2.6 8.5 8.6 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein FapA PF03961.13 EGC31862.1 - 3.6 6.1 11.6 4.6 5.7 11.6 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A FNIP PF05725.12 EGC31864.1 - 4.1e-152 494.2 99.2 6.9e-16 58.1 2.5 13.3 8 2 2 13 13 13 13 FNIP Repeat MCM_OB PF17207.3 EGC31864.1 - 0.23 11.3 0.0 1.4e+02 2.3 0.0 4.8 6 1 3 9 9 9 0 MCM OB domain Plus-3 PF03126.18 EGC31866.1 - 3e-27 95.3 1.3 4.1e-26 91.6 0.0 2.8 2 0 0 2 2 2 1 Plus-3 domain TAFH PF07531.14 EGC31866.1 - 0.008 16.3 0.7 0.062 13.4 0.0 2.4 1 1 1 2 2 2 1 NHR1 homology to TAF Meis_PKNOX_N PF16493.5 EGC31866.1 - 0.08 13.3 1.1 0.48 10.8 0.1 2.8 3 0 0 3 3 3 0 N-terminal of Homeobox Meis and PKNOX1 DUF1380 PF07128.12 EGC31866.1 - 0.13 12.5 0.1 1.9 8.6 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1380) NADH_B2 PF14813.6 EGC31867.1 - 0.0026 17.5 1.5 0.0028 17.4 1.5 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 ABC_membrane PF00664.23 EGC31868.1 - 2.8e-53 181.3 9.6 4.6e-53 180.6 9.6 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGC31868.1 - 6.5e-32 110.9 0.0 1.9e-31 109.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGC31868.1 - 1.1e-06 28.3 0.0 2.4e-06 27.2 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGC31868.1 - 0.0011 18.7 0.0 0.0033 17.2 0.0 1.7 1 1 0 1 1 1 1 AAA domain DEAD PF00270.29 EGC31868.1 - 0.043 13.6 0.2 0.22 11.3 0.0 2.1 2 1 0 2 2 2 0 DEAD/DEAH box helicase SbcCD_C PF13558.6 EGC31868.1 - 0.05 13.9 0.2 0.71 10.1 0.2 2.6 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit PRK PF00485.18 EGC31868.1 - 0.055 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EGC31868.1 - 0.066 12.5 0.2 0.4 9.9 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGC31868.1 - 0.073 13.5 0.2 0.38 11.2 0.2 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGC31868.1 - 0.084 12.8 0.2 1.9 8.4 0.0 2.3 2 0 0 2 2 2 0 NTPase AAA_22 PF13401.6 EGC31868.1 - 0.085 13.1 1.1 0.86 9.9 1.1 2.4 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGC31868.1 - 0.097 12.2 0.0 1.5 8.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain OTU PF02338.19 EGC31869.1 - 2.5e-11 44.2 0.1 3.1e-11 43.9 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4962 PF16332.5 EGC31869.1 - 0.03 12.8 0.6 0.04 12.4 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) OTU PF02338.19 EGC31870.1 - 2.8e-13 50.5 0.1 3.5e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease YhhN PF07947.14 EGC31872.1 - 6.4e-43 146.5 21.8 1.1e-42 145.7 21.8 1.4 1 0 0 1 1 1 1 YhhN family Mito_carr PF00153.27 EGC31873.1 - 6.6e-68 224.7 3.3 2.1e-26 91.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGC31873.1 - 0.01 15.0 0.1 0.094 11.9 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease DUF2987 PF11205.8 EGC31873.1 - 0.07 13.0 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2987) AAT PF03417.16 EGC31874.1 - 0.0034 17.1 0.0 0.0094 15.7 0.0 1.8 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase CBM_11 PF03425.13 EGC31874.1 - 0.072 13.0 1.6 0.38 10.6 1.6 2.0 1 1 0 1 1 1 0 Carbohydrate binding domain (family 11) Borrelia_orfD PF02999.14 EGC31874.1 - 0.083 13.2 1.7 8.4 6.8 0.1 2.2 2 0 0 2 2 2 0 Borrelia orf-D family His_Phos_2 PF00328.22 EGC31876.1 - 1.9e-24 86.7 0.0 7.1e-18 65.1 0.0 2.3 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.23 EGC31877.1 - 2.8e-11 43.4 0.0 5.3e-11 42.5 0.0 1.5 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ribonuc_P_40 PF08584.11 EGC31878.1 - 1.4e-62 211.6 0.0 2.2e-62 210.9 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Acetyltransf_13 PF13880.6 EGC31879.1 - 1.8e-26 91.9 0.0 3.8e-26 90.8 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.6 EGC31879.1 - 3e-13 49.3 0.9 6.2e-13 48.3 0.9 1.6 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_1 PF00583.25 EGC31879.1 - 2e-05 24.8 0.0 3.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC31879.1 - 0.00029 21.2 0.0 0.00065 20.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BRCT PF00533.26 EGC31880.1 - 0.14 12.6 2.2 0.27 11.7 0.1 2.6 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain bZIP_2 PF07716.15 EGC31880.1 - 6.7 6.9 10.7 2.8 8.1 0.9 3.7 3 0 0 3 3 3 0 Basic region leucine zipper LisH_2 PF16045.5 EGC31882.1 - 0.11 11.6 3.3 68 2.6 0.1 4.6 4 0 0 4 4 4 0 LisH PALP PF00291.25 EGC31883.1 - 1.7e-68 231.2 0.0 2.2e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.28 EGC31883.1 - 3e-18 66.0 0.0 3.3e-09 37.1 0.0 3.1 2 1 0 2 2 2 2 CBS domain DUF3879 PF12995.7 EGC31883.1 - 0.03 14.0 0.1 4.2 7.1 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function, E. rectale Gene description (DUF3879) Methyltransf_25 PF13649.6 EGC31884.1 - 1.5e-11 44.9 0.1 4.4e-11 43.3 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC31884.1 - 1.4e-10 41.2 0.0 2.9e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGC31884.1 - 2.9e-09 36.7 0.1 4.9e-09 36.0 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGC31884.1 - 6.7e-09 36.3 0.0 2.1e-08 34.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC31884.1 - 2e-08 34.2 0.0 1e-07 31.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC31884.1 - 7.3e-07 28.4 0.1 1.1e-06 27.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CMAS PF02353.20 EGC31884.1 - 8.4e-06 25.3 0.0 1.3e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGC31884.1 - 5.4e-05 22.8 0.2 8.8e-05 22.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain FtsJ PF01728.19 EGC31884.1 - 0.00012 22.3 0.1 0.00026 21.1 0.0 1.6 2 0 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.7 EGC31884.1 - 0.00028 20.9 0.1 0.00049 20.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.16 EGC31884.1 - 0.00042 20.2 0.0 0.00091 19.1 0.0 1.6 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Ubie_methyltran PF01209.18 EGC31884.1 - 0.00055 19.4 0.1 0.00085 18.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_16 PF10294.9 EGC31884.1 - 0.00067 19.4 0.1 0.0016 18.2 0.1 1.6 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_12 PF08242.12 EGC31884.1 - 0.00069 20.3 0.0 0.0016 19.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGC31884.1 - 0.0024 17.7 0.0 0.0039 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.14 EGC31884.1 - 0.0092 15.4 0.6 0.024 14.1 0.3 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.6 EGC31884.1 - 0.052 14.6 0.0 0.13 13.3 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain SPX PF03105.19 EGC31885.1 - 5.5 6.8 8.8 8.1 6.2 8.8 1.2 1 0 0 1 1 1 0 SPX domain DUF836 PF05768.14 EGC31886.1 - 3.6e-10 40.1 0.1 4.5e-10 39.8 0.1 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.24 EGC31886.1 - 0.052 13.8 0.0 0.099 12.9 0.0 1.6 1 1 0 1 1 1 0 Glutaredoxin GTP_EFTU PF00009.27 EGC31887.1 - 4e-60 202.7 0.3 7.3e-60 201.8 0.3 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGC31887.1 - 3.9e-25 87.7 0.1 1.1e-24 86.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGC31887.1 - 5.5e-17 61.6 3.4 6.7e-17 61.4 0.0 2.7 3 0 0 3 3 3 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGC31887.1 - 1.2e-12 48.1 1.8 4.3e-12 46.2 0.3 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGC31887.1 - 1.7e-10 40.7 0.0 4.9e-10 39.2 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV RF3_C PF16658.5 EGC31887.1 - 0.00011 22.1 0.0 0.00031 20.6 0.0 1.8 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGC31887.1 - 0.0041 17.2 0.3 0.014 15.5 0.1 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase TAP_C PF03943.13 EGC31888.1 - 5.6e-12 45.1 2.1 1.2e-11 44.0 2.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EGC31888.1 - 2.5e-05 24.8 0.1 0.00021 21.8 0.1 2.0 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF2451 PF10474.9 EGC31889.1 - 1.1e-71 241.3 0.4 1.1e-71 241.3 0.4 2.9 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) Vps54_N PF10475.9 EGC31889.1 - 2.3e-64 217.5 6.5 4.3e-54 183.8 0.8 2.8 1 1 1 2 2 2 2 Vacuolar-sorting protein 54, of GARP complex VHS PF00790.19 EGC31889.1 - 0.074 12.9 4.1 5.6 6.8 0.7 2.9 2 0 0 2 2 2 0 VHS domain DUF4745 PF15923.5 EGC31889.1 - 0.11 12.5 1.2 0.51 10.3 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4745) DUF3510 PF12022.8 EGC31889.1 - 0.16 12.4 0.0 0.16 12.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF3510) Mucin PF01456.17 EGC31890.1 - 0.54 10.2 9.5 0.072 13.1 3.8 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein Anoctamin PF04547.12 EGC31891.1 - 6.6e-100 335.1 19.8 8.4e-100 334.7 19.8 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Cid2 PF09774.9 EGC31892.1 - 5.3e-06 26.9 7.6 0.0013 19.2 0.7 2.5 1 1 1 2 2 2 2 Caffeine-induced death protein 2 Ydr279_N PF17745.1 EGC31892.1 - 0.047 13.9 0.2 0.053 13.8 0.2 1.3 1 1 0 1 1 1 0 Ydr279p protein triple barrel domain DUF413 PF04219.12 EGC31892.1 - 0.071 13.1 0.0 0.14 12.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF TFCD_C PF12612.8 EGC31893.1 - 3.6e-32 111.7 1.6 8.8e-32 110.5 0.0 2.6 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT PF02985.22 EGC31893.1 - 6.9e-06 25.9 0.0 0.96 9.9 0.0 5.2 5 0 0 5 5 5 2 HEAT repeat HEAT_EZ PF13513.6 EGC31893.1 - 7.7e-05 23.1 0.0 5.5 7.6 0.0 5.1 5 0 0 5 5 5 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGC31893.1 - 0.00021 21.8 2.3 0.28 11.8 0.0 5.7 3 3 4 7 7 6 1 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EGC31893.1 - 0.00035 20.4 0.8 2.9 7.6 0.0 4.5 4 0 0 4 4 4 2 rRNA processing/ribosome biogenesis HEAT_2 PF13646.6 EGC31893.1 - 0.019 15.3 0.1 35 4.9 0.0 4.6 5 1 0 5 5 5 0 HEAT repeats FKS1_dom1 PF14288.6 EGC31893.1 - 1.5 9.2 12.7 0.61 10.4 3.6 4.0 4 0 0 4 4 4 0 1,3-beta-glucan synthase subunit FKS1, domain-1 dUTPase PF00692.19 EGC31894.1 - 2.3e-45 153.4 0.0 2.7e-45 153.2 0.0 1.0 1 0 0 1 1 1 1 dUTPase TPR_2 PF07719.17 EGC31895.1 - 2.2e-21 74.2 1.0 0.0012 18.8 0.0 6.7 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGC31895.1 - 2.1e-16 59.0 9.2 0.0063 16.3 0.2 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGC31895.1 - 8.5e-14 51.1 0.2 0.034 15.0 0.0 5.7 4 2 1 5 5 5 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31895.1 - 8.4e-13 47.4 5.4 0.018 15.3 0.2 7.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC31895.1 - 6.4e-10 39.4 0.1 0.0024 18.4 0.0 4.6 3 1 0 4 4 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC31895.1 - 1.4e-09 38.0 7.2 2.4e-06 27.7 0.4 4.3 4 1 1 5 5 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGC31895.1 - 1.8e-07 30.7 0.2 0.14 11.8 0.0 5.2 4 1 1 5 5 5 2 TPR repeat TPR_16 PF13432.6 EGC31895.1 - 2.7e-07 31.1 0.0 0.0029 18.2 0.0 4.0 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC31895.1 - 2.3e-05 24.5 2.5 2.4 8.8 0.0 5.0 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC31895.1 - 6.2e-05 23.1 0.1 0.009 16.1 0.0 3.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31895.1 - 0.00015 21.5 2.1 11 6.3 0.0 5.5 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC31895.1 - 0.00052 20.3 5.7 2.7 8.4 0.0 4.8 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.6 EGC31895.1 - 0.00085 18.6 0.2 1.7 7.8 0.2 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC31895.1 - 0.0013 19.2 7.6 15 6.5 0.0 5.9 7 0 0 7 7 5 0 Tetratricopeptide repeat ChAPs PF09295.10 EGC31895.1 - 0.0052 15.8 1.7 0.052 12.5 0.1 2.5 1 1 1 2 2 2 1 ChAPs (Chs5p-Arf1p-binding proteins) CDC37_M PF08565.11 EGC31895.1 - 0.012 15.6 0.4 4.3 7.3 0.1 2.6 2 0 0 2 2 2 0 Cdc37 Hsp90 binding domain ANAPC5 PF12862.7 EGC31895.1 - 0.022 14.8 0.2 11 6.1 0.0 4.0 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 ATP-cone PF03477.16 EGC31895.1 - 1.8 9.2 6.0 68 4.1 0.7 4.4 4 1 0 4 4 3 0 ATP cone domain Peptidase_M41 PF01434.18 EGC31896.1 - 1.6e-60 204.2 3.3 4.8e-60 202.7 3.3 1.8 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.29 EGC31896.1 - 7.1e-43 146.2 0.0 1.5e-42 145.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC31896.1 - 6.5e-11 41.9 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC31896.1 - 1e-06 28.8 0.0 4.1e-06 26.8 0.0 2.1 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGC31896.1 - 4.3e-06 26.6 0.1 1.8e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGC31896.1 - 7e-06 26.5 0.3 0.0024 18.3 0.1 2.8 1 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC31896.1 - 0.0002 21.7 0.7 0.033 14.5 0.4 3.2 2 1 0 2 2 1 1 AAA domain AAA_7 PF12775.7 EGC31896.1 - 0.0011 18.5 0.1 0.013 15.0 0.1 2.4 1 1 0 1 1 1 1 P-loop containing dynein motor region ATPase PF06745.13 EGC31896.1 - 0.002 17.5 0.4 0.25 10.7 0.1 3.0 2 1 1 3 3 3 1 KaiC TIP49 PF06068.13 EGC31896.1 - 0.0027 17.0 0.1 0.0056 15.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EGC31896.1 - 0.0049 16.9 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE IstB_IS21 PF01695.17 EGC31896.1 - 0.0071 16.1 0.0 0.021 14.6 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_2 PF07724.14 EGC31896.1 - 0.01 16.0 0.0 0.029 14.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain (Cdc48 subfamily) Mg_chelatase PF01078.21 EGC31896.1 - 0.013 14.9 0.1 0.031 13.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGC31896.1 - 0.014 15.3 1.2 0.037 14.0 0.2 2.2 3 0 0 3 3 3 0 NACHT domain Sigma54_activat PF00158.26 EGC31896.1 - 0.017 14.8 0.0 0.055 13.2 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGC31896.1 - 0.023 14.0 0.4 0.076 12.3 0.1 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.6 EGC31896.1 - 0.034 13.9 0.0 0.63 9.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGC31896.1 - 0.042 13.0 0.0 0.12 11.5 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_14 PF13173.6 EGC31896.1 - 0.058 13.4 0.0 0.22 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC31896.1 - 0.15 12.6 0.2 0.83 10.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGC31896.1 - 2 8.7 4.0 10 6.4 0.4 3.0 2 1 0 2 2 2 0 AAA domain Mad3_BUB1_I_2 PF17014.5 EGC31897.1 - 0.0047 17.0 2.9 0.0047 17.0 2.9 1.9 1 1 1 2 2 2 1 Putative Mad3/BUB1 like region 1 protein zf-LYAR PF08790.11 EGC31898.1 - 9.9e-08 31.8 4.9 9.9e-08 31.8 4.9 2.6 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Glyco_hydro_25 PF01183.20 EGC31899.1 - 4.7e-14 53.0 0.1 5.3e-14 52.8 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1906 PF08924.11 EGC31899.1 - 0.027 14.6 1.5 0.048 13.8 0.9 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF1906) 2OG-FeII_Oxy_2 PF13532.6 EGC31900.1 - 2e-22 80.3 0.0 2.3e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4612 PF15389.6 EGC31900.1 - 0.56 11.3 12.8 1.5 9.9 4.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) SE PF08491.10 EGC31901.1 - 1.2e-98 329.5 0.0 1.7e-98 329.1 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.19 EGC31901.1 - 4.1e-14 52.6 0.0 1.3e-08 34.5 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGC31901.1 - 1.6e-05 24.2 0.5 0.0041 16.3 0.4 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGC31901.1 - 8.3e-05 22.3 0.0 0.026 14.1 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase Thi4 PF01946.17 EGC31901.1 - 0.00068 18.9 0.0 0.0019 17.5 0.0 1.8 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGC31901.1 - 0.0012 18.1 0.1 0.002 17.4 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC31901.1 - 0.0031 17.7 0.3 0.006 16.8 0.3 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGC31901.1 - 0.0093 15.1 0.1 0.44 9.5 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGC31901.1 - 0.025 13.4 0.2 19 3.9 0.1 3.0 2 1 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.22 EGC31901.1 - 0.03 13.4 2.7 0.12 11.4 2.7 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A FAD_oxidored PF12831.7 EGC31901.1 - 0.073 12.4 0.2 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase HI0933_like PF03486.14 EGC31901.1 - 0.092 11.4 0.1 0.16 10.6 0.1 1.4 1 0 0 1 1 1 0 HI0933-like protein Pyr_redox PF00070.27 EGC31901.1 - 0.12 12.9 0.1 0.34 11.5 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DDE_3 PF13358.6 EGC31902.1 - 0.053 13.3 0.1 0.071 12.9 0.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease FANCI_S1 PF14675.6 EGC31904.1 - 1.9e-51 174.8 7.3 1.9e-51 174.8 7.3 3.8 4 1 0 4 4 4 1 FANCI solenoid 1 FANCI_S4 PF14678.6 EGC31904.1 - 8.8e-48 162.6 10.0 8.8e-48 162.6 10.0 6.0 7 0 0 7 7 7 1 FANCI solenoid 4 FANCI_S2 PF14676.6 EGC31904.1 - 2.2e-33 115.9 2.6 2.2e-33 115.9 2.6 3.9 3 0 0 3 3 3 1 FANCI solenoid 2 FANCI_HD2 PF14680.6 EGC31904.1 - 7.1e-33 113.8 4.6 7.1e-33 113.8 4.6 3.8 4 1 0 4 4 4 1 FANCI helical domain 2 FANCI_HD1 PF14679.6 EGC31904.1 - 0.0007 19.5 7.2 0.0057 16.6 0.1 4.5 3 1 0 3 3 3 1 FANCI helical domain 1 Adaptin_binding PF10199.9 EGC31905.1 - 0.035 14.7 3.3 0.059 14.0 3.3 1.3 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DnaJ PF00226.31 EGC31906.1 - 1.4e-16 60.4 1.0 3.3e-16 59.2 0.1 2.3 2 0 0 2 2 2 1 DnaJ domain MAS20 PF02064.15 EGC31906.1 - 0.014 15.5 0.8 0.035 14.2 0.8 1.6 1 0 0 1 1 1 0 MAS20 protein import receptor RNA_pol_Rpb2_6 PF00562.28 EGC31907.1 - 1e-110 370.5 0.1 2.8e-110 369.1 0.1 1.7 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGC31907.1 - 4.3e-37 127.6 0.1 8.1e-37 126.7 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.16 EGC31907.1 - 2.3e-28 98.1 0.0 4.5e-28 97.2 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.20 EGC31907.1 - 3.5e-23 81.8 0.1 7.4e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.14 EGC31907.1 - 8e-19 68.0 0.0 1.8e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.12 EGC31907.1 - 1.2e-16 60.5 0.2 5.8e-16 58.2 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_4 PF04566.13 EGC31907.1 - 0.061 13.6 0.0 0.18 12.1 0.0 1.9 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 Sld5 PF05916.11 EGC31908.1 - 3.8e-20 72.4 0.4 3.8e-20 72.4 0.4 1.6 2 0 0 2 2 2 1 GINS complex protein EcoRII-C PF09019.11 EGC31908.1 - 0.0014 18.8 0.3 0.0061 16.7 0.3 2.0 1 1 0 1 1 1 1 EcoRII C terminal Dimer_Tnp_hAT PF05699.14 EGC31909.1 - 8.4e-18 63.9 0.1 8.6e-18 63.9 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5517 PF17639.2 EGC31910.1 - 0.054 13.8 0.0 0.2 11.9 0.0 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5517) Inositol_P PF00459.25 EGC31911.1 - 2.9e-49 168.0 0.0 4.3e-49 167.5 0.0 1.2 1 1 0 1 1 1 1 Inositol monophosphatase family DNA_primase_lrg PF04104.14 EGC31911.1 - 0.033 13.6 0.0 0.062 12.7 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic and archaeal DNA primase, large subunit TIG PF01833.24 EGC31914.1 - 3.4e-36 123.2 68.1 1.8e-09 37.5 8.0 10.7 9 2 2 11 11 11 8 IPT/TIG domain EGF_2 PF07974.13 EGC31914.1 - 0.0018 18.6 13.8 0.0041 17.5 13.8 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGC31914.1 - 0.0026 17.8 8.6 0.0066 16.6 8.6 1.7 1 0 0 1 1 1 1 Laminin EGF domain EGF PF00008.27 EGC31914.1 - 0.3 11.4 8.8 0.93 9.9 8.8 1.9 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGC31914.1 - 2.5 8.2 8.9 7.8 6.7 8.9 1.9 1 0 0 1 1 1 0 Tenascin EGF domain TFIIA PF03153.13 EGC31915.1 - 5e-08 33.4 16.7 6.7e-08 32.9 16.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-rbx1 PF12678.7 EGC31915.1 - 6.9e-06 26.3 7.7 1.9e-05 24.9 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC31915.1 - 7.9e-06 25.6 10.8 1.3e-05 25.0 10.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC31915.1 - 1.2e-05 25.5 13.4 2.2e-05 24.7 13.4 1.4 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGC31915.1 - 0.0001 22.1 10.1 0.0002 21.1 10.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGC31915.1 - 0.00014 21.6 11.2 0.00026 20.7 11.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31915.1 - 0.00038 20.3 13.0 0.00079 19.2 13.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC31915.1 - 0.063 13.5 7.5 0.16 12.1 7.5 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC31915.1 - 0.086 12.8 11.5 0.17 11.9 11.5 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC31915.1 - 0.71 10.0 6.6 0.8 9.8 5.2 1.9 1 1 0 1 1 1 0 RING-type zinc-finger YabA PF06156.13 EGC31916.1 - 0.11 13.1 9.1 0.83 10.3 1.6 2.6 1 1 1 2 2 2 0 Initiation control protein YabA Toxin_trans PF07952.12 EGC31916.1 - 0.43 9.6 8.3 0.32 10.0 6.3 1.8 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain AhpC-TSA PF00578.21 EGC31918.1 - 7.5e-44 148.6 0.0 8.7e-44 148.4 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC31918.1 - 1.9e-26 92.5 0.0 2.2e-26 92.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EGC31918.1 - 9.9e-05 22.3 0.1 0.00015 21.7 0.1 1.4 1 1 0 1 1 1 1 SCO1/SenC Thioredoxin_8 PF13905.6 EGC31918.1 - 0.00021 21.5 0.0 0.00032 21.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 EGC31918.1 - 0.017 15.2 0.0 0.022 14.8 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PAT1 PF09770.9 EGC31919.1 - 4.4e-07 28.6 1.5 4.4e-07 28.6 1.5 4.2 1 1 2 3 3 3 2 Topoisomerase II-associated protein PAT1 DUF3439 PF11921.8 EGC31919.1 - 0.016 15.1 16.9 0.016 15.1 1.4 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC31919.1 - 9.8 6.2 38.0 1.4 8.9 5.0 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein FancD2 PF14631.6 EGC31920.1 - 1.9e-99 333.8 36.4 1.9e-86 290.7 26.1 7.5 6 2 1 7 7 7 4 Fanconi anaemia protein FancD2 nuclease FANCI_S2 PF14676.6 EGC31920.1 - 0.0012 19.2 0.2 0.0012 19.2 0.2 3.5 4 0 0 4 4 4 1 FANCI solenoid 2 CNDH2_C PF16858.5 EGC31920.1 - 0.042 13.7 0.2 0.042 13.7 0.2 4.4 3 1 1 4 4 4 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term CLASP_N PF12348.8 EGC31921.1 - 4.1e-15 56.0 19.7 6.4e-09 35.7 0.3 6.3 6 2 1 7 7 7 3 CLASP N terminal HEAT PF02985.22 EGC31921.1 - 6.4e-11 41.5 4.2 0.086 13.1 0.0 8.2 8 0 0 8 8 8 2 HEAT repeat Cnd1 PF12717.7 EGC31921.1 - 1.7e-06 28.2 23.7 0.033 14.2 0.1 8.7 5 3 4 9 9 9 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGC31921.1 - 0.00016 22.2 7.2 19 5.9 0.0 8.1 7 4 3 10 10 10 1 Vacuolar 14 Fab1-binding region TAN PF11640.8 EGC31921.1 - 0.003 17.7 4.8 2.1 8.5 0.4 5.1 4 1 0 4 4 4 2 Telomere-length maintenance and DNA damage repair baeRF_family7 PF18849.1 EGC31921.1 - 0.0088 16.3 0.3 0.066 13.4 0.1 2.6 2 0 0 2 2 2 1 Bacterial archaeo-eukaryotic release factor family 7 ParcG PF10274.9 EGC31921.1 - 0.01 16.0 6.1 0.79 9.8 0.3 5.2 4 1 0 4 4 4 0 Parkin co-regulated protein HEAT_EZ PF13513.6 EGC31921.1 - 0.045 14.3 2.3 21 5.8 0.0 5.4 7 0 0 7 7 7 0 HEAT-like repeat WRW PF10206.9 EGC31921.1 - 0.16 12.3 0.0 0.69 10.3 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial F1F0-ATP synthase, subunit f ATP-synt_DE_N PF02823.16 EGC31922.1 - 8.3e-18 64.1 0.0 1.3e-17 63.4 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain HHH_5 PF14520.6 EGC31925.1 - 0.0023 18.5 0.1 0.0043 17.6 0.1 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF763 PF05559.11 EGC31925.1 - 0.011 15.0 0.7 0.013 14.8 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Na_Ca_ex_C PF16494.5 EGC31925.1 - 0.061 13.8 0.7 0.093 13.2 0.7 1.4 1 0 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain CSG2 PF16965.5 EGC31925.1 - 0.93 8.4 5.1 1.1 8.1 5.1 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator HhH-GPD PF00730.25 EGC31926.1 - 4.2e-19 69.0 0.0 3.4e-17 62.9 0.0 2.6 2 0 0 2 2 2 1 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.6 EGC31926.1 - 1.2e-11 44.5 0.0 8.8e-10 38.6 0.0 2.4 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.23 EGC31926.1 - 2.2e-05 24.1 0.1 4.9e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif DUF382 PF04037.13 EGC31926.1 - 0.0036 17.4 1.0 0.011 15.9 1.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF382) HHH_5 PF14520.6 EGC31926.1 - 0.039 14.6 0.1 0.14 12.8 0.1 1.9 1 1 1 2 2 2 0 Helix-hairpin-helix domain DUF3858 PF12970.7 EGC31926.1 - 0.59 10.2 4.7 1.5 8.9 4.7 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3858) EndIII_4Fe-2S PF10576.9 EGC31926.1 - 4.1 7.9 6.3 1.7 9.1 2.2 2.3 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III FAM176 PF14851.6 EGC31926.1 - 5 6.8 15.9 2.1 8.0 6.6 2.6 2 0 0 2 2 2 0 FAM176 family PTPRCAP PF15713.5 EGC31926.1 - 7 6.9 13.0 0.094 13.0 1.7 2.2 2 0 0 2 2 2 0 Protein tyrosine phosphatase receptor type C-associated CAF-1_p150 PF11600.8 EGC31927.1 - 0.092 12.4 17.9 0.22 11.2 17.9 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TetR_C_26 PF17934.1 EGC31928.1 - 0.12 12.7 0.0 0.35 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain Ribosomal_L16 PF00252.18 EGC31930.1 - 1.8e-41 141.2 0.1 2.3e-41 140.9 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SET PF00856.28 EGC31931.1 - 5.6e-10 39.9 0.0 6.7e-08 33.1 0.0 2.5 1 1 0 1 1 1 1 SET domain Ank_3 PF13606.6 EGC31931.1 - 0.00078 19.7 0.0 0.035 14.6 0.0 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.7 EGC31931.1 - 0.0019 18.8 0.0 0.0063 17.1 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) YmgB PF10798.8 EGC31931.1 - 0.011 15.5 0.0 0.024 14.5 0.0 1.5 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF3447 PF11929.8 EGC31931.1 - 0.013 15.4 1.1 0.49 10.4 0.1 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3447) Ank_4 PF13637.6 EGC31931.1 - 0.062 13.9 0.0 0.2 12.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) DUF3430 PF11912.8 EGC31933.1 - 0.0016 18.6 58.1 0.1 12.7 15.3 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF3430) Cathelicidins PF00666.17 EGC31933.1 - 0.052 13.9 5.4 2.5 8.5 0.1 3.6 3 1 0 3 3 3 0 Cathelicidin WD40 PF00400.32 EGC31934.1 - 2.2e-16 59.9 11.4 3.1e-06 27.8 0.6 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC31934.1 - 6.4e-08 32.8 2.5 0.15 12.4 0.0 5.1 4 2 2 6 6 5 2 Anaphase-promoting complex subunit 4 WD40 domain YabA PF06156.13 EGC31934.1 - 0.00071 20.2 15.6 0.0023 18.5 15.6 1.9 1 0 0 1 1 1 1 Initiation control protein YabA DUF1513 PF07433.11 EGC31934.1 - 0.0065 15.6 0.0 0.05 12.7 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) Nup54_57_C PF18570.1 EGC31934.1 - 0.0071 15.9 0.4 0.0071 15.9 0.4 1.9 2 0 0 2 2 1 1 NUP57/Nup54 C-terminal domain Syntaxin-6_N PF09177.11 EGC31934.1 - 0.0075 16.8 8.8 0.0075 16.8 8.8 2.3 1 1 1 2 2 2 1 Syntaxin 6, N-terminal V_ATPase_I PF01496.19 EGC31934.1 - 0.015 13.2 18.0 0.023 12.6 18.0 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Macoilin PF09726.9 EGC31934.1 - 0.078 11.5 13.2 0.11 11.0 13.2 1.2 1 0 0 1 1 1 0 Macoilin family LMBR1 PF04791.16 EGC31934.1 - 0.11 11.4 10.5 0.14 11.0 10.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PQQ_3 PF13570.6 EGC31934.1 - 0.26 11.8 0.6 11 6.7 0.1 2.8 3 0 0 3 3 3 0 PQQ-like domain HAUS6_N PF14661.6 EGC31934.1 - 0.42 10.1 12.8 0.76 9.3 12.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus APG6_N PF17675.1 EGC31934.1 - 0.44 11.1 19.2 1 9.9 19.2 1.6 1 0 0 1 1 1 0 Apg6 coiled-coil region SKA1 PF07160.12 EGC31934.1 - 0.88 9.4 25.0 0.13 12.1 19.2 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 YfhD PF14151.6 EGC31934.1 - 1.3 9.2 8.5 3.3 7.9 8.5 1.7 1 0 0 1 1 1 0 YfhD-like protein SPT6_acidic PF14632.6 EGC31934.1 - 2 9.1 11.8 3.3 8.3 11.1 1.7 1 1 0 1 1 1 0 Acidic N-terminal SPT6 MCC-bdg_PDZ PF10506.9 EGC31934.1 - 2.6 8.1 7.3 8.4 6.5 2.1 2.6 1 1 1 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome DUF948 PF06103.11 EGC31934.1 - 3.5 7.9 7.8 1.8 8.8 4.4 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) SprA-related PF12118.8 EGC31934.1 - 4.6 6.3 20.8 0.45 9.6 15.9 1.7 2 0 0 2 2 2 0 SprA-related family UPF0242 PF06785.11 EGC31934.1 - 9.2 6.3 22.9 20 5.3 22.9 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus zf-RING_2 PF13639.6 EGC31936.1 - 1.1e-07 32.1 10.5 1.1e-07 32.1 10.5 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC31936.1 - 8.1e-07 28.8 7.2 2.1e-06 27.5 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC31936.1 - 5.5e-06 26.2 11.2 5.5e-06 26.2 11.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC31936.1 - 5.3e-05 23.0 9.3 5.3e-05 23.0 9.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC31936.1 - 0.00025 21.3 5.9 0.00025 21.3 5.9 3.0 4 1 0 4 4 4 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC31936.1 - 0.0075 16.2 9.8 0.0075 16.2 9.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC31936.1 - 0.02 14.9 5.7 0.02 14.9 5.7 2.0 2 0 0 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC31936.1 - 0.054 13.7 8.1 0.2 11.9 8.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC31936.1 - 0.24 11.2 8.2 0.65 9.8 8.2 1.8 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC31936.1 - 0.85 9.7 7.4 0.05 13.7 1.3 2.1 3 0 0 3 3 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dapper PF15268.6 EGC31936.1 - 2.9 6.6 37.3 4.3 6.1 37.3 1.2 1 0 0 1 1 1 0 Dapper FNIP PF05725.12 EGC31937.1 - 7.5e-218 704.6 50.9 6.2e-14 51.9 0.1 14.3 3 2 13 19 19 19 19 FNIP Repeat DUF3215 PF11503.8 EGC31937.1 - 0.41 10.5 1.5 24 4.9 0.0 5.2 7 0 0 7 7 7 0 Protein of unknown function (DUF3215) Methyltransf_15 PF09445.10 EGC31939.1 - 3.8e-32 111.2 0.2 4.8e-32 110.8 0.2 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Cons_hypoth95 PF03602.15 EGC31939.1 - 5.6e-05 22.9 0.0 7.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.6 EGC31939.1 - 0.0041 17.8 0.0 0.0068 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.18 EGC31939.1 - 0.026 14.2 0.2 1.4 8.6 0.2 2.1 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 PrmA PF06325.13 EGC31939.1 - 0.11 11.8 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Rtf2 PF04641.12 EGC31940.1 - 4.2e-74 249.2 10.9 4.9e-74 249.0 10.9 1.1 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EGC31940.1 - 0.0012 18.7 0.6 0.003 17.4 0.7 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 Peptidase_C107 PF17222.3 EGC31940.1 - 0.023 13.7 1.8 0.031 13.3 1.8 1.3 1 1 0 1 1 1 0 Viral cysteine endopeptidase C107 Prok-RING_1 PF14446.6 EGC31940.1 - 0.085 12.8 0.1 0.2 11.6 0.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Vps39_2 PF10367.9 EGC31940.1 - 0.21 12.0 5.7 0.22 12.0 0.1 2.7 1 1 2 3 3 3 0 Vacuolar sorting protein 39 domain 2 zf-RING_5 PF14634.6 EGC31940.1 - 0.25 11.3 1.3 0.48 10.4 1.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Mucin PF01456.17 EGC31940.1 - 1.7 8.6 13.3 2.6 8.0 13.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3799 PF12684.7 EGC31941.1 - 0.0041 16.9 0.3 0.0041 16.9 0.3 1.0 1 0 0 1 1 1 1 PDDEXK-like domain of unknown function (DUF3799) Acyl-CoA_dh_1 PF00441.24 EGC31942.1 - 9.2e-45 152.5 0.0 1.4e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGC31942.1 - 1.8e-30 105.9 0.0 2.9e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGC31942.1 - 3.6e-26 91.2 0.0 9.6e-26 89.8 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC31942.1 - 2.8e-20 73.0 0.0 4.4e-20 72.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain AcylCoA_dehyd_C PF12186.8 EGC31942.1 - 0.021 14.9 0.3 0.76 9.9 0.2 2.3 2 0 0 2 2 2 0 Acyl-CoA dehydrogenase C terminal Abhydrolase_1 PF00561.20 EGC31942.1 - 0.14 11.8 0.2 0.63 9.6 0.0 2.1 2 1 1 3 3 3 0 alpha/beta hydrolase fold Patatin PF01734.22 EGC31943.1 - 6.9e-17 62.3 0.0 7.5e-16 58.9 0.0 2.3 1 1 0 1 1 1 1 Patatin-like phospholipase PAH PF02671.21 EGC31944.1 - 0.00046 20.3 2.9 0.00046 20.3 2.9 1.7 2 0 0 2 2 2 1 Paired amphipathic helix repeat CCM2_C PF16545.5 EGC31944.1 - 0.035 14.6 0.1 0.056 14.0 0.1 1.3 1 0 0 1 1 1 0 Cerebral cavernous malformation protein, harmonin-homology DSPc PF00782.20 EGC31945.1 - 1.2e-25 89.8 0.2 1.4e-25 89.7 0.2 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC31945.1 - 0.00085 19.0 0.2 0.015 14.9 0.1 1.9 1 1 1 2 2 2 2 Protein-tyrosine phosphatase p450 PF00067.22 EGC31946.1 - 1.1e-84 284.8 0.1 1.3e-84 284.6 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 TCR_zetazeta PF11628.8 EGC31946.1 - 0.11 12.2 1.0 0.32 10.7 1.0 1.9 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 zeta chain DNA_pol_B PF00136.21 EGC31947.1 - 8.2e-113 377.5 4.0 8.2e-113 377.5 4.0 2.1 2 0 0 2 2 2 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGC31947.1 - 1.6e-34 119.5 6.1 1.6e-34 119.5 6.1 2.7 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.10 EGC31947.1 - 1.9e-27 96.2 12.3 1.9e-27 96.2 12.3 2.5 3 0 0 3 3 3 1 DNA Polymerase alpha zinc finger Pepsin-I3 PF06394.13 EGC31947.1 - 0.012 15.8 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Phage_int_SAM_3 PF14659.6 EGC31947.1 - 0.48 10.7 5.3 0.98 9.7 0.3 3.2 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain DUF2369 PF10179.9 EGC31947.1 - 0.86 10.0 3.9 1.5 9.3 0.0 3.2 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2369) ATG_C PF09333.11 EGC31948.1 - 5.3e-13 49.1 0.0 2.9e-12 46.8 0.0 2.2 1 1 1 2 2 2 1 Autophagy-related protein C terminal domain Chorein_N PF12624.7 EGC31948.1 - 5.6e-09 36.1 2.4 5.6e-09 36.1 2.4 3.8 3 0 0 3 3 3 1 N-terminal region of Chorein or VPS13 VPS13_C PF16909.5 EGC31948.1 - 2.6e-05 24.1 0.7 2.6e-05 24.1 0.7 4.3 2 1 2 4 4 4 1 Vacuolar-sorting-associated 13 protein C-terminal Rhomboid PF01694.22 EGC31949.1 - 2e-36 125.3 14.3 2e-36 125.3 14.3 1.6 2 0 0 2 2 2 1 Rhomboid family DUF4491 PF14898.6 EGC31949.1 - 1.9 9.0 9.7 0.24 11.9 0.6 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF4491) OHCU_decarbox PF09349.10 EGC31950.1 - 2.6e-38 132.0 0.2 6.4e-38 130.7 0.0 1.7 2 0 0 2 2 2 1 OHCU decarboxylase Amidohydro_1 PF01979.20 EGC31950.1 - 2.2e-25 89.7 0.0 9.6e-25 87.6 0.0 1.8 2 0 0 2 2 2 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGC31950.1 - 7.7e-10 38.8 0.0 9.7e-08 31.9 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Acetyltransf_3 PF13302.7 EGC31952.1 - 6.5e-13 49.5 0.0 7.4e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC31952.1 - 0.00039 20.6 0.0 0.0024 18.1 0.0 1.9 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family YoaP PF14268.6 EGC31952.1 - 0.084 12.4 0.5 0.22 11.0 0.1 1.8 2 0 0 2 2 2 0 YoaP-like FR47 PF08445.10 EGC31952.1 - 0.1 12.6 0.0 0.26 11.3 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein RhoGEF PF00621.20 EGC31953.1 - 1.1e-30 107.2 8.4 1.8e-30 106.6 8.4 1.3 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.27 EGC31953.1 - 6.4e-06 25.5 0.4 1.2e-05 24.7 0.4 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif RecG_N PF17190.4 EGC31953.1 - 5.7 7.7 6.5 4.6 8.0 2.0 2.8 2 1 1 3 3 3 0 RecG N-terminal helical domain Pkinase PF00069.25 EGC31954.1 - 1.1e-72 244.6 0.0 2.4e-72 243.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31954.1 - 3.2e-46 157.7 0.0 5.2e-46 157.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.32 EGC31954.1 - 1.9e-28 98.1 32.1 8.7e-05 23.2 0.2 8.6 8 0 0 8 8 8 7 WD domain, G-beta repeat PB1 PF00564.24 EGC31954.1 - 2.4e-14 53.0 0.1 5.3e-14 51.9 0.1 1.6 1 0 0 1 1 1 1 PB1 domain F-box PF00646.33 EGC31954.1 - 2.7e-07 30.3 0.4 7.2e-07 28.9 0.4 1.7 1 0 0 1 1 1 1 F-box domain Kinase-like PF14531.6 EGC31954.1 - 2.1e-05 24.0 0.1 0.0084 15.5 0.1 2.7 2 1 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGC31954.1 - 2.7e-05 23.2 0.4 9.5e-05 21.3 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase F-box-like PF12937.7 EGC31954.1 - 5.9e-05 22.9 0.1 0.00014 21.7 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGC31954.1 - 0.00025 19.8 6.6 0.53 8.9 0.1 4.3 2 1 1 5 5 5 2 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGC31954.1 - 0.00034 20.9 1.1 1.3 9.4 0.0 4.1 3 2 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Hydin_ADK PF17213.3 EGC31954.1 - 0.055 13.7 2.1 0.1 12.8 2.1 1.4 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Beta_helix PF13229.6 EGC31955.1 - 8.9e-07 28.9 31.6 8.9e-07 28.9 31.6 3.9 2 1 0 3 3 3 1 Right handed beta helix region PIH1 PF08190.12 EGC31955.1 - 0.17 11.4 6.0 0.22 11.0 0.3 2.5 2 0 0 2 2 2 0 PIH1 N-terminal domain Pex24p PF06398.11 EGC31956.1 - 5e-05 22.5 0.5 5e-05 22.5 0.5 3.4 1 1 2 3 3 3 1 Integral peroxisomal membrane peroxin Trypan_PARP PF05887.11 EGC31956.1 - 0.0011 19.0 27.8 0.0011 19.0 27.8 2.2 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) DUF4551 PF15087.6 EGC31956.1 - 0.63 8.8 8.5 0.91 8.3 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) eIF3_p135 PF12807.7 EGC31956.1 - 4.1 7.4 6.8 0.23 11.5 1.1 1.8 2 0 0 2 2 2 0 Translation initiation factor eIF3 subunit 135 Latrophilin PF02354.16 EGC31956.1 - 6.8 5.6 9.5 8.7 5.3 9.5 1.1 1 0 0 1 1 1 0 Latrophilin Cytoplasmic C-terminal region Gaa1 PF04114.14 EGC31957.1 - 7.8e-42 143.9 21.1 2.2e-41 142.4 21.1 1.8 1 1 0 1 1 1 1 Gaa1-like, GPI transamidase component LIM PF00412.22 EGC31958.1 - 3.5e-12 46.3 5.7 5.5e-12 45.7 5.7 1.3 1 0 0 1 1 1 1 LIM domain DUF3005 PF11448.8 EGC31958.1 - 0.0018 18.3 6.2 0.013 15.6 0.9 2.5 1 1 1 2 2 2 2 Protein of unknown function (DUF3005) CDC37_C PF08564.10 EGC31958.1 - 0.024 14.7 0.9 9 6.5 0.1 2.8 1 1 1 2 2 2 0 Cdc37 C terminal domain zf-C5HC2 PF02928.16 EGC31958.1 - 0.19 12.1 2.7 0.74 10.2 0.3 2.2 2 0 0 2 2 2 0 C5HC2 zinc finger DUF4665 PF15679.5 EGC31958.1 - 0.27 11.9 7.8 1.6 9.4 1.6 3.4 1 1 2 3 3 3 0 Domain of unknown function (DUF4665) CBM_15 PF03426.14 EGC31958.1 - 0.27 10.8 10.5 3 7.4 0.9 2.8 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) zinc_ribbon_12 PF11331.8 EGC31958.1 - 0.45 10.3 3.0 0.83 9.5 3.0 1.4 1 0 0 1 1 1 0 Probable zinc-ribbon domain Dicty_spore_N PF04562.12 EGC31959.1 - 1.5e-30 106.2 21.6 1.5e-30 106.2 21.6 5.6 2 1 3 5 5 5 1 Dictyostelium spore coat protein, N terminus Ribosomal_L28e PF01778.17 EGC31960.1 - 1.4e-33 116.1 0.3 1.4e-33 116.1 0.3 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.14 EGC31960.1 - 3.7e-24 85.2 15.9 3.7e-24 85.2 15.9 2.4 1 1 1 2 2 2 1 Mak16 protein C-terminal region BUD22 PF09073.10 EGC31960.1 - 0.00011 21.7 11.2 0.00014 21.4 11.2 1.1 1 0 0 1 1 1 1 BUD22 TauE PF01925.19 EGC31962.1 - 2.6e-27 96.0 17.1 7.8e-25 87.9 17.1 2.1 1 1 0 1 1 1 1 Sulfite exporter TauE/SafE Pox_A30L_A26L PF06086.12 EGC31962.1 - 0.046 13.4 0.0 2.4 7.8 0.0 2.4 2 0 0 2 2 2 0 Orthopoxvirus A26L/A30L protein PBP PF01161.20 EGC31963.1 - 1.5e-28 99.7 0.0 1.9e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein S1_2 PF13509.6 EGC31964.1 - 0.03 14.4 0.7 6.1 7.0 0.1 2.9 3 0 0 3 3 3 0 S1 domain Ras PF00071.22 EGC31965.1 - 1.2e-46 158.3 0.1 1.4e-46 158.0 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31965.1 - 7.5e-24 84.2 0.0 1.1e-23 83.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC31965.1 - 5.3e-14 52.1 0.1 6e-14 51.9 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC31965.1 - 2.4e-09 36.9 0.1 3e-09 36.6 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC31965.1 - 2.9e-06 27.0 0.2 7e-06 25.7 0.1 1.6 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC31965.1 - 1.6e-05 24.9 0.0 0.027 14.4 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGC31965.1 - 8.4e-05 22.1 0.1 0.00016 21.2 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC31965.1 - 0.00091 19.3 0.0 0.0017 18.4 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGC31965.1 - 0.0012 18.1 1.3 0.14 11.2 0.0 2.8 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.6 EGC31965.1 - 0.0029 18.0 0.0 0.0063 16.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain MMR_HSR1_Xtn PF16897.5 EGC31965.1 - 0.0089 16.0 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain Septin PF00735.18 EGC31965.1 - 0.0094 15.3 0.0 0.015 14.5 0.0 1.3 1 0 0 1 1 1 1 Septin cobW PF02492.19 EGC31965.1 - 0.01 15.4 0.3 1.6 8.3 0.0 2.2 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain FeoB_N PF02421.18 EGC31965.1 - 0.011 15.2 0.2 0.31 10.6 0.0 2.5 2 1 1 3 3 3 0 Ferrous iron transport protein B CBM27 PF09212.10 EGC31965.1 - 0.038 14.2 0.2 2.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Carbohydrate binding module 27 AAA_22 PF13401.6 EGC31965.1 - 0.038 14.3 0.0 0.072 13.4 0.0 1.7 1 1 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGC31965.1 - 0.05 12.7 0.0 0.071 12.2 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_7 PF12775.7 EGC31965.1 - 0.057 12.9 0.0 0.099 12.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_29 PF13555.6 EGC31965.1 - 0.092 12.5 0.1 0.19 11.5 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EGC31965.1 - 0.12 11.6 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_5 PF07728.14 EGC31965.1 - 0.18 11.8 0.0 0.38 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribonuc_2-5A PF06479.12 EGC31966.1 - 7.5e-13 48.8 11.0 5e-12 46.1 10.2 2.5 1 1 1 2 2 2 1 Ribonuclease 2-5A Pkinase PF00069.25 EGC31966.1 - 3.5e-12 46.3 2.1 6.5e-11 42.1 0.0 2.5 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC31966.1 - 0.00014 21.3 0.6 0.00089 18.6 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Ku_N PF03731.15 EGC31966.1 - 0.017 14.9 5.5 0.035 13.9 3.9 2.1 1 1 1 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain Cnd1 PF12717.7 EGC31967.1 - 2.2e-05 24.6 1.7 2.7e-05 24.2 0.1 1.9 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGC31967.1 - 7.8e-05 22.6 0.2 0.068 13.5 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGC31967.1 - 0.00053 20.3 0.0 0.0012 19.2 0.0 1.6 1 0 0 1 1 1 1 HEAT repeats Vac14_Fab1_bd PF12755.7 EGC31967.1 - 0.034 14.7 0.1 0.19 12.3 0.0 2.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region ribosomal_L24 PF17136.4 EGC31968.1 - 1.5e-15 57.3 0.4 3.6e-15 56.1 0.4 1.7 1 0 0 1 1 1 1 Ribosomal proteins 50S L24/mitochondrial 39S L24 KOW PF00467.29 EGC31968.1 - 9.6e-09 34.9 0.5 4.5e-08 32.8 1.3 1.8 2 0 0 2 2 2 1 KOW motif Josephin PF02099.17 EGC31969.1 - 5.6e-16 59.1 3.3 1.5e-14 54.4 3.3 2.1 1 1 0 1 1 1 1 Josephin APG6 PF04111.12 EGC31970.1 - 4e-49 167.0 1.3 1.4e-48 165.2 1.3 2.1 1 0 0 1 1 1 1 Apg6 BARA domain APG6_N PF17675.1 EGC31970.1 - 2.5 8.6 29.5 0.67 10.5 25.6 2.2 2 0 0 2 2 2 0 Apg6 coiled-coil region TPR_1 PF00515.28 EGC31972.1 - 4.4e-06 26.3 1.0 1.3e-05 24.8 0.1 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC31972.1 - 0.00031 20.6 0.4 0.0017 18.3 0.0 2.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC31972.1 - 0.00094 19.2 0.1 0.00094 19.2 0.1 3.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC31972.1 - 0.0052 16.7 0.0 0.02 14.9 0.0 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat HSP70 PF00012.20 EGC31973.1 - 2.4e-262 871.5 10.5 2.8e-262 871.3 10.5 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGC31973.1 - 1.5e-14 53.6 0.2 4.3e-13 48.8 0.1 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.16 EGC31973.1 - 0.00027 20.7 0.0 0.00087 19.1 0.0 1.8 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.18 EGC31973.1 - 0.0013 18.0 0.1 0.0034 16.7 0.1 1.7 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase DDR PF08841.10 EGC31973.1 - 0.025 13.6 0.3 0.21 10.5 0.2 2.1 2 0 0 2 2 2 0 Diol dehydratase reactivase ATPase-like domain Rotamase PF00639.21 EGC31973.1 - 0.039 14.9 3.9 0.12 13.3 3.4 2.1 1 1 0 1 1 1 0 PPIC-type PPIASE domain DUF4364 PF14277.6 EGC31973.1 - 0.044 13.5 4.6 0.19 11.5 4.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4364) DUF2115 PF09888.9 EGC31973.1 - 0.34 11.4 2.4 0.42 11.1 0.4 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Tetraspanin PF00335.20 EGC31974.1 - 2.9e-34 118.8 12.9 3.4e-34 118.5 12.9 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2976 PF11190.8 EGC31974.1 - 0.0037 17.0 1.7 0.0037 17.0 1.7 2.9 3 1 0 3 3 3 1 Protein of unknown function (DUF2976) DUF1206 PF06724.11 EGC31974.1 - 0.0068 16.5 4.3 0.013 15.5 1.3 2.4 2 0 0 2 2 2 1 Domain of Unknown Function (DUF1206) DUF2569 PF10754.9 EGC31974.1 - 0.013 15.9 12.6 0.025 15.0 8.6 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2569) TrbL PF04610.14 EGC31974.1 - 0.018 14.8 1.3 0.018 14.8 1.3 2.9 3 0 0 3 3 3 0 TrbL/VirB6 plasmid conjugal transfer protein UPF0182 PF03699.13 EGC31974.1 - 0.12 10.5 1.9 0.13 10.3 1.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) FA_desaturase PF00487.24 EGC31974.1 - 0.14 12.0 0.3 0.21 11.4 0.3 1.3 1 0 0 1 1 1 0 Fatty acid desaturase CcmH PF03918.14 EGC31974.1 - 0.19 11.0 0.2 0.19 11.0 0.2 2.6 1 1 3 4 4 4 0 Cytochrome C biogenesis protein PorA PF11271.8 EGC31974.1 - 0.3 10.3 3.7 1.6 8.0 0.0 2.2 2 0 0 2 2 2 0 Porin PorA DUF373 PF04123.13 EGC31974.1 - 0.31 10.5 7.7 0.2 11.0 2.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF373) TRIQK PF15168.6 EGC31974.1 - 0.38 10.7 0.1 0.38 10.7 0.1 3.2 2 1 2 4 4 4 0 Triple QxxK/R motif-containing protein family ABC2_membrane_2 PF12679.7 EGC31974.1 - 0.87 8.8 7.7 1.1 8.5 7.2 1.5 1 1 0 1 1 1 0 ABC-2 family transporter protein Wzy_C PF04932.15 EGC31974.1 - 0.94 9.1 10.5 1 9.0 2.3 2.5 1 1 1 2 2 2 0 O-Antigen ligase TarH PF02203.15 EGC31974.1 - 1.5 8.7 3.3 7.1 6.5 0.2 2.6 2 0 0 2 2 2 0 Tar ligand binding domain homologue DUF898 PF05987.13 EGC31974.1 - 1.6 7.7 8.9 0.47 9.5 4.5 1.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.9 EGC31974.1 - 2.2 7.0 16.7 11 4.7 1.7 2.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Ninjurin PF04923.12 EGC31974.1 - 6.4 6.8 13.0 0.32 10.9 0.9 2.6 2 1 0 2 2 2 0 Ninjurin STE3 PF02076.15 EGC31974.1 - 9.1 5.4 12.8 0.62 9.2 4.1 2.8 2 1 1 3 3 3 0 Pheromone A receptor Jagunal PF07086.12 EGC31974.1 - 9.6 6.2 8.8 0.81 9.7 0.5 2.7 2 1 1 3 3 3 0 Jagunal, ER re-organisation during oogenesis ATG13 PF10033.9 EGC31977.1 - 1.9e-17 63.8 2.4 2e-15 57.1 0.1 2.7 1 1 1 2 2 2 2 Autophagy-related protein 13 Ribosomal_S2 PF00318.20 EGC31978.1 - 1.6e-22 79.8 0.4 2.8e-12 46.3 0.1 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 NIPSNAP PF07978.13 EGC31979.1 - 4.6e-18 65.3 0.0 8e-17 61.3 0.0 2.1 2 0 0 2 2 2 1 NIPSNAP RRM_2 PF04059.12 EGC31982.1 - 2e-26 92.1 0.5 2.1e-26 92.0 0.5 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 Smg4_UPF3 PF03467.15 EGC31982.1 - 4.3e-05 23.6 0.3 4.9e-05 23.4 0.3 1.0 1 0 0 1 1 1 1 Smg-4/UPF3 family RRM_1 PF00076.22 EGC31982.1 - 0.0001 22.1 0.5 0.00013 21.7 0.5 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.12 EGC31982.1 - 0.0026 17.9 0.6 0.0033 17.6 0.6 1.2 1 0 0 1 1 1 1 BRCA1-associated protein 2 PHM7_cyt PF14703.6 EGC31982.1 - 0.046 13.9 0.3 1.6 8.9 0.0 2.1 1 1 0 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter ALMT PF11744.8 EGC31983.1 - 0.018 13.9 1.4 0.027 13.3 1.4 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter EBV-NA3 PF05009.12 EGC31983.1 - 0.054 13.0 5.7 0.045 13.3 1.4 2.5 2 1 1 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) CSRNP_N PF16019.5 EGC31983.1 - 0.12 12.2 0.4 0.21 11.5 0.4 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus GOLD_2 PF13897.6 EGC31983.1 - 0.17 12.4 2.5 0.36 11.3 2.5 1.5 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking DUF4637 PF15470.6 EGC31983.1 - 0.33 10.7 3.4 0.61 9.8 3.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) NOA36 PF06524.12 EGC31983.1 - 0.72 9.1 11.3 1.5 8.1 11.3 1.5 1 0 0 1 1 1 0 NOA36 protein DUF2722 PF10846.8 EGC31983.1 - 0.73 8.7 9.1 1.1 8.1 9.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DUF4611 PF15387.6 EGC31983.1 - 1 9.6 14.4 10 6.4 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) TFB6 PF17110.5 EGC31983.1 - 1.1 9.0 6.0 2.2 8.0 6.0 1.4 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH DUF2457 PF10446.9 EGC31983.1 - 3 6.9 12.3 5.3 6.1 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MINDY_DUB PF04424.13 EGC31984.1 - 3.9e-27 94.6 0.0 9.7e-27 93.3 0.0 1.7 1 0 0 1 1 1 1 MINDY deubiquitinase Vert_HS_TF PF06546.11 EGC31984.1 - 0.0065 16.2 5.4 0.0065 16.2 5.4 1.8 2 0 0 2 2 2 1 Vertebrate heat shock transcription factor STATa_Ig PF18214.1 EGC31988.1 - 2.7e-48 163.0 1.6 3.4e-48 162.7 0.1 2.0 2 1 0 2 2 2 1 STATa Immunoglobulin-like domain Dict-STAT-coil PF09267.10 EGC31988.1 - 4.1e-43 146.4 15.2 6.5e-43 145.7 15.2 1.3 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil EF-hand_12 PF17901.1 EGC31988.1 - 2e-42 143.5 1.6 3.9e-42 142.6 1.6 1.5 1 0 0 1 1 1 1 EF-hand fold domain SH2 PF00017.24 EGC31988.1 - 1.5e-08 34.6 0.0 4e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 SH2 domain Cbl_N3 PF02762.14 EGC31988.1 - 0.03 14.2 0.0 0.074 12.9 0.0 1.6 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain DPPIV_N PF00930.21 EGC31989.1 - 1.4e-62 211.5 12.9 2.3e-62 210.8 10.0 2.0 1 1 1 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.21 EGC31989.1 - 2.6e-46 157.8 0.0 5e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.18 EGC31989.1 - 3.1e-06 27.0 0.0 5.3e-05 22.9 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Esterase PF00756.20 EGC31989.1 - 0.00011 21.9 0.0 0.00022 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.8 EGC31989.1 - 0.04 13.2 0.0 0.11 11.7 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 AXE1 PF05448.12 EGC31989.1 - 0.041 12.6 0.1 1.2 7.7 0.1 2.4 1 1 0 1 1 1 0 Acetyl xylan esterase (AXE1) DLH PF01738.18 EGC31989.1 - 0.07 12.7 0.3 3.2 7.3 0.0 2.5 3 0 0 3 3 3 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGC31989.1 - 0.075 12.8 0.1 0.63 9.8 0.0 2.3 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Alba PF01918.21 EGC31990.1 - 2.2e-12 46.6 0.2 3.9e-12 45.8 0.2 1.4 1 0 0 1 1 1 1 Alba NAC PF01849.18 EGC31991.1 - 2.1e-16 59.6 0.0 5.9e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 NAC domain DUF507 PF04368.13 EGC31991.1 - 0.43 10.5 4.1 0.25 11.3 1.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF507) PhoLip_ATPase_C PF16212.5 EGC31992.1 - 7.8e-87 291.2 21.1 7.8e-87 291.2 21.1 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC31992.1 - 1.6e-26 91.8 5.0 1.6e-26 91.8 5.0 3.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGC31992.1 - 1.2e-13 51.0 0.1 1.1e-12 47.8 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC31992.1 - 1.3e-12 48.5 0.2 9.7e-05 22.7 0.0 3.3 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGC31992.1 - 7.3e-10 38.7 0.0 2.2e-09 37.1 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGC31992.1 - 0.91 9.2 10.1 0.054 13.2 0.5 3.2 3 1 0 3 3 3 0 haloacid dehalogenase-like hydrolase NTF2 PF02136.20 EGC31993.1 - 1.5e-18 67.5 0.0 1.8e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.9 EGC31993.1 - 1.7e-05 24.8 0.0 2.3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 DUF4518 PF15008.6 EGC31993.1 - 0.12 11.5 0.1 0.18 10.9 0.1 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4518) RRM_1 PF00076.22 EGC31994.1 - 1.5e-17 63.1 2.9 5.3e-11 42.2 0.1 3.0 4 0 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FNIP PF05725.12 EGC31994.1 - 1.9e-15 56.7 19.8 1.6e-07 31.3 0.5 5.3 4 1 1 5 5 5 3 FNIP Repeat RRM_occluded PF16842.5 EGC31994.1 - 1.9e-06 27.6 0.0 0.022 14.6 0.0 2.7 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_3 PF08777.11 EGC31994.1 - 0.012 15.7 0.5 3 7.9 0.1 3.5 2 1 1 3 3 3 0 RNA binding motif RNA_bind PF08675.11 EGC31994.1 - 0.049 13.6 0.0 56 3.9 0.0 3.4 3 0 0 3 3 3 0 RNA binding domain ArfGap PF01412.18 EGC31995.1 - 3.5e-40 136.7 0.0 3.5e-40 136.7 0.0 3.9 4 0 0 4 4 2 1 Putative GTPase activating protein for Arf BAR_3 PF16746.5 EGC31995.1 - 1.7e-19 70.5 14.2 7.1e-19 68.5 14.2 2.1 1 0 0 1 1 1 1 BAR domain of APPL family PH PF00169.29 EGC31995.1 - 1.5e-17 64.0 0.2 1.5e-17 64.0 0.2 3.3 3 0 0 3 3 3 1 PH domain BAR PF03114.18 EGC31995.1 - 3e-13 50.0 10.2 9.9e-13 48.3 10.2 1.9 1 0 0 1 1 1 1 BAR domain Ank_4 PF13637.6 EGC31995.1 - 8.8e-11 42.1 0.0 1.5e-05 25.4 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC31995.1 - 3.3e-10 40.4 0.0 8.3e-10 39.1 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) BAR_2 PF10455.9 EGC31995.1 - 2.5e-08 33.4 8.7 2.5e-08 33.4 8.7 5.0 5 1 0 6 6 4 1 Bin/amphiphysin/Rvs domain for vesicular trafficking Ank_5 PF13857.6 EGC31995.1 - 3.9e-08 33.4 0.0 3.9e-08 33.4 0.0 2.3 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC31995.1 - 1.4e-06 28.5 0.0 0.14 12.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat PH_11 PF15413.6 EGC31995.1 - 1.4e-05 25.5 0.1 1.4e-05 25.5 0.1 4.9 4 1 0 4 4 3 1 Pleckstrin homology domain Ank_3 PF13606.6 EGC31995.1 - 5.8e-05 23.2 0.0 0.45 11.2 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat PH_9 PF15410.6 EGC31995.1 - 0.0061 16.9 0.1 0.037 14.4 0.1 2.4 1 0 0 1 1 1 1 Pleckstrin homology domain Acyltransf_C PF16076.5 EGC31995.1 - 0.064 13.4 0.9 7.4 6.7 0.6 2.8 2 0 0 2 2 2 0 Acyltransferase C-terminus Ras PF00071.22 EGC31996.1 - 1.8e-31 109.0 0.0 2e-31 108.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC31996.1 - 9e-07 29.1 0.0 1.6e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGC31996.1 - 0.028 13.9 0.0 0.028 13.9 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain 7tm_2 PF00002.24 EGC31999.1 - 8.7e-11 41.6 22.8 1.2e-10 41.1 22.8 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGC31999.1 - 9.2e-08 31.6 28.3 1.3e-07 31.1 28.3 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Zip PF02535.22 EGC32000.1 - 4.1e-31 108.4 16.9 4.4e-24 85.3 0.2 3.0 2 1 1 3 3 3 3 ZIP Zinc transporter ATP_synt_H PF05493.13 EGC32000.1 - 0.13 12.8 4.8 0.16 12.5 1.6 2.6 3 0 0 3 3 3 0 ATP synthase subunit H Acetyltransf_3 PF13302.7 EGC32001.1 - 8.5e-27 94.5 0.0 9.8e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC32001.1 - 1.9e-10 41.1 0.3 2.3e-10 40.8 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC32001.1 - 1.6e-06 28.4 0.3 2.4e-06 27.8 0.3 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Amidase PF01425.21 EGC32002.1 - 1.4e-132 442.9 0.0 1.7e-132 442.6 0.0 1.0 1 0 0 1 1 1 1 Amidase zf-RING_2 PF13639.6 EGC32004.1 - 6.1e-07 29.7 8.3 9.9e-07 29.0 8.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC32004.1 - 5.2e-06 26.2 7.1 9.1e-06 25.4 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC32004.1 - 6.4e-06 25.9 8.8 1.1e-05 25.2 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC32004.1 - 0.0008 19.4 4.7 0.0015 18.5 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC32004.1 - 0.0015 18.3 6.0 0.0025 17.7 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC32004.1 - 0.005 17.0 2.9 0.013 15.6 2.9 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC32004.1 - 0.014 15.4 8.1 0.023 14.6 8.1 1.3 1 0 0 1 1 1 0 zinc-RING finger domain FYVE_2 PF02318.16 EGC32004.1 - 0.016 15.4 4.8 0.03 14.5 4.8 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-rbx1 PF12678.7 EGC32004.1 - 0.054 13.8 8.3 0.15 12.4 8.3 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGC32004.1 - 0.65 9.8 8.6 1.3 8.8 8.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 EGC32004.1 - 1.4 9.2 10.0 3.1 8.1 10.0 1.7 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Orf78 PF06024.12 EGC32005.1 - 0.0056 17.0 0.0 0.0056 17.0 0.0 2.9 2 1 0 2 2 2 1 Orf78 (ac78) DUF4448 PF14610.6 EGC32005.1 - 0.012 15.4 0.0 0.033 14.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) Chlam_PMP PF02415.17 EGC32005.1 - 0.082 13.4 51.8 1.8 9.2 0.2 9.7 8 1 1 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat BUD22 PF09073.10 EGC32005.1 - 0.35 10.2 9.0 0.46 9.8 9.0 1.1 1 0 0 1 1 1 0 BUD22 DUF1980 PF09323.10 EGC32005.1 - 3.6 7.5 8.7 17 5.2 8.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) SLC35F PF06027.12 EGC32006.1 - 3.2e-97 325.7 27.6 3.6e-97 325.5 27.6 1.0 1 0 0 1 1 1 1 Solute carrier family 35 CRT-like PF08627.10 EGC32006.1 - 2.5e-12 46.4 10.8 2.5e-12 46.4 10.8 1.5 1 1 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like EamA PF00892.20 EGC32006.1 - 7e-12 45.7 36.3 1.1e-07 32.1 12.7 2.1 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGC32006.1 - 0.01 15.1 23.7 0.036 13.3 23.9 1.9 1 1 0 1 1 1 0 UAA transporter family NDUF_B4 PF07225.12 EGC32007.1 - 0.042 13.7 0.1 0.046 13.6 0.1 1.1 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) PWI PF01480.17 EGC32008.1 - 9e-24 83.6 0.0 1.5e-23 82.9 0.0 1.3 1 0 0 1 1 1 1 PWI domain PSCyt2 PF07583.11 EGC32008.1 - 0.0093 15.9 0.0 0.011 15.7 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) Pkinase PF00069.25 EGC32009.1 - 3.5e-70 236.4 0.0 4.6e-70 236.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32009.1 - 5.8e-51 173.3 0.0 8.5e-51 172.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1241 PF06840.11 EGC32009.1 - 3.1e-07 30.2 0.2 1.2e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) Kinase-like PF14531.6 EGC32009.1 - 2e-05 24.1 0.0 0.0035 16.7 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase_fungal PF17667.1 EGC32009.1 - 8.1e-05 21.6 0.6 0.00029 19.8 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC32009.1 - 0.0024 16.9 0.1 0.045 12.7 0.1 2.2 1 1 0 1 1 1 1 Haspin like kinase domain Kdo PF06293.14 EGC32009.1 - 0.2 11.0 0.0 0.56 9.5 0.0 1.6 1 1 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Hamartin PF04388.12 EGC32009.1 - 0.32 9.6 5.7 0.41 9.3 5.7 1.2 1 0 0 1 1 1 0 Hamartin protein SOG2 PF10428.9 EGC32009.1 - 0.39 9.9 9.8 0.53 9.4 9.8 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein TFIIF_alpha PF05793.12 EGC32009.1 - 1.6 7.2 9.1 2.3 6.7 9.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FNIP PF05725.12 EGC32010.1 - 4e-28 97.3 35.5 3e-11 43.3 2.0 5.9 4 2 1 6 6 6 5 FNIP Repeat Cag12 PF13117.6 EGC32010.1 - 6 7.5 9.0 31 5.2 4.1 2.3 1 1 1 2 2 2 0 Cag pathogenicity island protein Cag12 CBM49 PF09478.10 EGC32011.1 - 3.1e-16 59.4 0.5 4.5e-16 58.9 0.5 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Actin PF00022.19 EGC32012.1 - 1.4e-82 277.5 0.0 1.9e-81 273.8 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGC32012.1 - 0.22 10.3 0.0 3.1 6.5 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein PCI PF01399.27 EGC32013.1 - 9.6e-16 58.2 2.0 9.6e-16 58.2 2.0 2.9 3 0 0 3 3 3 1 PCI domain eIF3m_C_helix PF18005.1 EGC32013.1 - 3.2e-10 39.5 3.8 6.8e-10 38.5 3.8 1.6 1 0 0 1 1 1 1 eIF3 subunit M, C-terminal helix Transcrip_act PF04949.13 EGC32013.1 - 0.008 16.1 0.5 0.067 13.1 0.2 2.6 1 1 1 2 2 2 1 Transcriptional activator KTI12 PF08433.10 EGC32015.1 - 5.8e-10 39.1 15.4 5.1e-06 26.1 9.6 3.2 2 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGC32015.1 - 0.0003 21.0 0.0 0.00075 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC32015.1 - 0.003 18.1 0.0 0.003 18.1 0.0 3.0 1 1 1 2 2 2 1 AAA domain AAA PF00004.29 EGC32015.1 - 0.095 13.1 0.1 0.3 11.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.6 EGC32015.1 - 0.24 11.4 11.4 5.1 7.2 11.2 3.0 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGC32015.1 - 0.25 11.7 0.0 0.46 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF2408 PF10303.9 EGC32015.1 - 5.7 7.5 11.3 0.3 11.6 3.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) Ndc80_HEC PF03801.13 EGC32016.1 - 0.17 11.5 3.3 6.6 6.3 0.0 3.6 4 0 0 4 4 4 0 HEC/Ndc80p family Imm25 PF15564.6 EGC32016.1 - 0.19 11.7 3.4 7.4 6.5 0.8 2.4 2 0 0 2 2 2 0 Immunity protein 25 Uricase PF01014.18 EGC32017.1 - 2.8e-58 195.8 3.0 9.9e-35 119.7 0.3 2.1 2 0 0 2 2 2 2 Uricase FolB PF02152.18 EGC32017.1 - 0.0034 17.9 0.0 1.7 9.3 0.0 2.2 2 0 0 2 2 2 2 Dihydroneopterin aldolase RrnaAD PF00398.20 EGC32018.1 - 1.4e-38 132.5 1.2 1e-37 129.7 0.0 2.7 3 1 0 3 3 3 1 Ribosomal RNA adenine dimethylase Methyltransf_25 PF13649.6 EGC32018.1 - 0.022 15.4 0.0 0.07 13.8 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGC32018.1 - 0.25 11.3 0.0 0.25 11.3 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32019.1 - 2.7e-24 85.7 0.0 4.4e-24 85.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32019.1 - 1.4e-20 73.7 0.0 2.9e-20 72.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32019.1 - 4.7e-19 68.9 0.0 8.8e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC32019.1 - 1.3e-13 50.8 0.0 2.1e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGC32019.1 - 1.3e-11 44.7 0.0 1.8e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC32019.1 - 8.8e-11 42.4 0.3 1.2e-09 38.8 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PCMT PF01135.19 EGC32019.1 - 6.2e-10 39.2 0.0 8.8e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.20 EGC32019.1 - 1.5e-06 27.7 0.0 2.2e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EGC32019.1 - 2.9e-06 27.0 0.0 5.2e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.16 EGC32019.1 - 8.7e-05 21.8 0.2 0.0032 16.6 0.1 2.2 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_8 PF05148.15 EGC32019.1 - 0.0016 18.3 0.3 0.0068 16.3 0.3 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EGC32019.1 - 0.0027 17.7 0.6 0.0075 16.3 0.1 1.9 1 1 1 2 2 2 1 Methyltransferase domain DREV PF05219.12 EGC32019.1 - 0.011 14.9 0.0 0.014 14.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase TPMT PF05724.11 EGC32019.1 - 0.014 15.0 0.0 0.026 14.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) MTS PF05175.14 EGC32019.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase small domain Fibrillarin PF01269.17 EGC32019.1 - 0.018 14.2 0.0 0.024 13.8 0.0 1.3 1 0 0 1 1 1 0 Fibrillarin HSP20 PF00011.21 EGC32020.1 - 4.2e-06 26.8 0.0 1.1e-05 25.6 0.0 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4207 PF13904.6 EGC32020.1 - 0.0019 17.9 4.1 0.0019 17.9 4.1 2.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) MCR PF18509.1 EGC32021.1 - 0.085 12.4 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Magnetochrome domain Spheroidin PF05541.12 EGC32022.1 - 3e-17 61.8 3.3 4.6e-17 61.2 3.3 1.2 1 0 0 1 1 1 1 Entomopoxvirus spheroidin protein Abdominal-A PF12407.8 EGC32022.1 - 0.18 11.4 0.1 0.35 10.5 0.1 1.3 1 0 0 1 1 1 0 Homeobox protein Glyco_transf_10 PF00852.19 EGC32023.1 - 1.8e-37 128.8 0.7 5.4e-37 127.2 0.7 1.8 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGC32023.1 - 1.1e-08 35.4 0.5 4.9e-08 33.3 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1035 PF06281.12 EGC32023.1 - 7.1 6.7 6.2 5 7.2 3.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) TPR_19 PF14559.6 EGC32024.1 - 5.5e-26 90.9 11.4 0.00056 20.4 0.0 13.4 13 1 0 13 13 13 6 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32024.1 - 1.2e-23 81.2 36.5 0.0016 18.4 0.1 16.9 19 0 0 19 19 17 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32024.1 - 5.6e-23 79.7 0.0 0.12 13.2 0.0 11.6 13 1 2 15 15 8 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32024.1 - 2.6e-19 67.8 46.1 0.047 13.9 0.0 16.9 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32024.1 - 9.9e-17 60.1 37.5 0.079 13.4 0.1 15.8 18 0 0 18 18 17 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32024.1 - 1.4e-13 51.0 11.0 0.066 13.5 0.0 11.1 10 1 0 11 11 11 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC32024.1 - 3.1e-12 46.9 0.3 0.37 11.5 0.0 9.0 10 1 1 11 11 9 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32024.1 - 2e-11 43.4 30.1 0.16 11.7 0.8 12.9 14 1 1 15 15 14 3 TPR repeat TPR_1 PF00515.28 EGC32024.1 - 5.5e-11 41.8 45.5 0.0069 16.2 0.1 14.3 16 0 0 16 16 13 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32024.1 - 1.5e-06 27.8 11.7 9.7 6.5 0.0 10.5 12 0 0 12 12 10 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC32024.1 - 1.9e-06 28.0 44.9 0.13 12.5 0.1 11.5 11 1 1 13 13 13 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC32024.1 - 3.4e-06 27.3 22.7 4.5 8.1 0.0 11.5 14 0 0 14 14 8 1 Tetratricopeptide repeat ChAPs PF09295.10 EGC32024.1 - 3.5e-06 26.3 24.7 0.00012 21.3 3.5 6.5 5 2 1 6 6 6 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_MalT PF17874.1 EGC32024.1 - 8e-06 25.4 4.7 0.013 14.9 0.1 5.2 5 2 1 6 6 6 2 MalT-like TPR region TPR_15 PF13429.6 EGC32024.1 - 6.8e-05 22.2 14.3 0.15 11.2 0.0 6.5 4 3 1 6 6 6 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32024.1 - 0.0016 18.2 15.6 0.019 14.8 0.0 6.7 6 0 0 6 6 5 1 Tetratricopeptide repeat EH_Signature PF15611.6 EGC32024.1 - 0.0018 17.8 0.0 0.094 12.1 0.0 2.5 2 0 0 2 2 2 1 EH_Signature domain TPR_9 PF13371.6 EGC32024.1 - 0.0058 16.8 0.0 4 7.7 0.0 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat BTAD PF03704.17 EGC32024.1 - 0.015 15.7 1.0 2.7 8.4 0.1 3.1 3 0 0 3 3 3 0 Bacterial transcriptional activator domain RPN7 PF10602.9 EGC32024.1 - 0.054 13.2 15.0 0.21 11.3 0.4 5.8 6 1 1 7 7 6 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.6 EGC32024.1 - 0.11 12.5 19.7 2.9 8.0 0.0 7.9 8 1 0 8 8 7 0 Fis1 C-terminal tetratricopeptide repeat Tissue_fac PF01108.17 EGC32024.1 - 0.12 12.2 1.0 0.48 10.3 1.0 2.0 1 0 0 1 1 1 0 Tissue factor TPR_21 PF09976.9 EGC32024.1 - 0.42 10.3 17.2 11 5.7 0.0 7.4 8 2 0 10 10 9 0 Tetratricopeptide repeat-like domain Cytochrom_B562 PF07361.11 EGC32024.1 - 1.4 9.6 8.1 0.24 12.1 0.4 3.9 4 0 0 4 4 2 0 Cytochrome b562 DHR10 PF18595.1 EGC32024.1 - 1.8 8.7 7.8 2 8.5 0.0 4.6 5 1 1 6 6 6 0 Designed helical repeat protein 10 domain DUF3971 PF13116.6 EGC32025.1 - 0.091 12.3 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF410 PF04190.13 EGC32025.1 - 0.11 12.3 0.1 0.16 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF410) RasGEF PF00617.19 EGC32027.1 - 5.1e-33 114.7 1.7 5.1e-33 114.7 1.7 2.5 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.27 EGC32027.1 - 1.3e-15 57.5 0.2 4.6e-15 55.7 0.2 2.0 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.20 EGC32027.1 - 1.4e-14 54.2 0.4 1.4e-14 54.2 0.4 3.3 4 0 0 4 4 4 1 RasGEF N-terminal motif ETRAMP PF09716.10 EGC32028.1 - 1.6 8.9 7.0 0.11 12.5 0.5 2.4 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) PhoLip_ATPase_C PF16212.5 EGC32029.1 - 2.8e-78 263.1 30.8 2.8e-78 263.1 30.8 2.1 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal Cation_ATPase PF13246.6 EGC32029.1 - 1.7e-12 47.2 0.1 7.3e-11 42.0 0.0 2.6 2 0 0 2 2 2 1 Cation transport ATPase (P-type) E1-E2_ATPase PF00122.20 EGC32029.1 - 3.2e-10 39.8 0.0 3.6e-09 36.4 0.0 2.7 2 1 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGC32029.1 - 1.6e-09 38.4 0.0 0.0012 19.2 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC32029.1 - 0.00076 19.3 0.3 0.0064 16.3 0.0 2.6 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Nrap_D2 PF17403.2 EGC32030.1 - 0.0015 18.3 0.1 0.0021 17.8 0.1 1.2 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain RNA_lig_T4_1 PF09511.10 EGC32031.1 - 1.2e-44 152.8 0.1 2.3e-44 151.9 0.1 1.4 1 0 0 1 1 1 1 RNA ligase zf-UBR PF02207.20 EGC32032.1 - 0.0015 18.7 11.5 0.0033 17.6 11.5 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF3698 PF12479.8 EGC32032.1 - 0.041 14.4 1.3 0.71 10.4 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3698) Leg1 PF05612.12 EGC32033.1 - 2e-52 178.4 5.7 2.7e-52 178.0 5.7 1.1 1 0 0 1 1 1 1 Leg1 DUF1374 PF07118.11 EGC32033.1 - 7 7.2 10.9 1.2 9.7 1.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1374) WD40 PF00400.32 EGC32034.1 - 5.4e-17 61.9 3.0 0.0063 17.3 0.1 5.4 5 0 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32034.1 - 0.00027 21.2 0.0 1.7 9.0 0.0 3.6 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGC32034.1 - 0.028 14.5 0.0 8.7 6.4 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Frtz PF11768.8 EGC32034.1 - 0.029 12.7 0.0 1.4 7.1 0.1 2.5 3 0 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PQQ_3 PF13570.6 EGC32034.1 - 0.081 13.4 0.2 30 5.3 0.0 4.3 5 1 0 5 5 5 0 PQQ-like domain PQQ PF01011.21 EGC32034.1 - 0.28 11.2 1.1 8.9 6.4 0.2 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Myb_DNA-binding PF00249.31 EGC32035.1 - 6.3e-06 26.3 1.0 1.6e-05 25.0 1.0 1.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain Endosulfine PF04667.17 EGC32036.1 - 9.7e-09 35.3 0.2 1.5e-08 34.6 0.1 1.4 1 1 1 2 2 2 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ras PF00071.22 EGC32037.1 - 4.1e-59 198.8 0.1 4.9e-59 198.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32037.1 - 1.1e-21 77.3 0.0 4.1e-21 75.4 0.0 1.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32037.1 - 1.3e-09 37.8 0.0 1.7e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC32037.1 - 2e-05 24.3 0.1 2.9e-05 23.7 0.1 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC32037.1 - 0.00016 21.6 0.1 0.48 10.3 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase FeoB_N PF02421.18 EGC32037.1 - 0.035 13.6 0.1 0.097 12.2 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B MMR_HSR1 PF01926.23 EGC32037.1 - 0.037 14.1 0.0 0.056 13.5 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase BCDHK_Adom3 PF10436.9 EGC32037.1 - 0.058 13.2 0.1 0.089 12.6 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase AAA_22 PF13401.6 EGC32037.1 - 0.08 13.2 0.6 5.4 7.3 0.0 2.4 2 1 0 3 3 3 0 AAA domain baeRF_family3 PF18845.1 EGC32037.1 - 0.092 13.0 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 3 DUF4878 PF12870.7 EGC32037.1 - 0.1 12.9 1.3 0.17 12.2 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4878) AAA PF00004.29 EGC32037.1 - 0.15 12.5 0.1 9.5 6.7 0.0 2.4 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) DNA_binding_2 PF13724.6 EGC32037.1 - 0.21 12.0 0.3 0.35 11.3 0.3 1.4 1 0 0 1 1 1 0 DNA-binding domain DUF2663 PF10864.8 EGC32038.1 - 1.3 9.4 7.6 4.2 7.8 0.5 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2663) FNIP PF05725.12 EGC32039.1 - 5.2e-66 218.6 62.1 5.8e-16 58.4 3.2 8.3 5 2 3 9 9 9 9 FNIP Repeat Terpene_synth PF01397.21 EGC32039.1 - 0.091 12.4 0.7 1.4 8.6 0.0 3.0 4 0 0 4 4 4 0 Terpene synthase, N-terminal domain RIG-I_C PF18119.1 EGC32039.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 RIG-I receptor C-terminal domain LRR_adjacent PF08191.11 EGC32039.1 - 0.19 12.0 1.7 26 5.1 0.1 3.7 3 1 0 3 3 3 0 LRR adjacent RhoGEF PF00621.20 EGC32040.1 - 7.8e-46 156.6 1.6 2.6e-45 154.9 1.6 2.0 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.27 EGC32040.1 - 0.0012 18.4 0.3 0.0025 17.4 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH_16 PF17838.1 EGC32040.1 - 0.0041 16.9 0.2 1.2 9.0 0.1 2.8 2 0 0 2 2 2 2 PH domain SOGA PF11365.8 EGC32040.1 - 5.7 8.1 7.9 3.4 8.9 2.0 3.1 2 0 0 2 2 2 0 Protein SOGA ANAPC4_WD40 PF12894.7 EGC32041.1 - 2.1e-11 43.9 0.1 2.4e-05 24.5 0.0 3.9 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC32041.1 - 3.5e-11 43.4 3.2 3.7e-05 24.4 0.1 4.7 4 1 0 4 4 4 2 WD domain, G-beta repeat Cytochrom_D1 PF02239.16 EGC32041.1 - 0.00016 20.3 0.0 0.00028 19.6 0.0 1.3 1 0 0 1 1 1 1 Cytochrome D1 heme domain ELYS-bb PF16687.5 EGC32041.1 - 0.019 13.6 0.2 0.44 9.1 0.0 2.5 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin DUF4254 PF14063.6 EGC32041.1 - 0.093 12.5 0.8 0.21 11.4 0.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4254) HA2 PF04408.23 EGC32042.1 - 6.6e-25 87.5 0.0 1.3e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC32042.1 - 4.5e-21 75.0 0.1 9e-21 74.0 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGC32042.1 - 3.8e-13 49.7 0.0 7.3e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vinculin PF01044.19 EGC32043.1 - 2.9e-43 148.3 52.8 5.9e-24 84.4 28.8 3.2 2 1 1 3 3 3 3 Vinculin family T2SSF PF00482.23 EGC32043.1 - 0.092 12.7 3.8 0.2 11.6 0.5 3.3 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F DUF1460 PF07313.12 EGC32043.1 - 0.69 9.3 6.3 0.56 9.6 0.0 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1460) SPACA9 PF15120.6 EGC32043.1 - 0.74 9.6 10.7 0.47 10.2 0.5 3.8 4 0 0 4 4 4 0 Sperm acrosome-associated protein 9 PALP PF00291.25 EGC32044.1 - 2.5e-61 207.7 0.0 3.1e-61 207.4 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Rota_NSP3 PF01665.16 EGC32045.1 - 0.036 13.2 0.0 0.037 13.2 0.0 1.0 1 0 0 1 1 1 0 Rotavirus non-structural protein NSP3 CreD PF06123.12 EGC32046.1 - 0.0066 15.3 0.5 0.0077 15.1 0.5 1.0 1 0 0 1 1 1 1 Inner membrane protein CreD Gti1_Pac2 PF09729.9 EGC32046.1 - 0.38 10.8 13.7 0.5 10.4 13.7 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Presenilin PF01080.17 EGC32046.1 - 4.3 6.0 11.9 5.4 5.7 11.9 1.1 1 0 0 1 1 1 0 Presenilin HCO3_cotransp PF00955.21 EGC32046.1 - 6.1 5.5 6.4 6.8 5.4 6.4 1.3 1 0 0 1 1 1 0 HCO3- transporter family eIF2A PF08662.11 EGC32047.1 - 1.8e-60 204.1 9.3 8.1e-58 195.5 4.0 4.2 2 1 1 4 4 4 3 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGC32047.1 - 0.0016 16.6 0.3 0.0016 16.6 0.3 2.0 2 0 0 2 2 2 1 IKI3 family RRM_1 PF00076.22 EGC32047.1 - 0.01 15.6 0.0 0.044 13.6 0.0 2.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HA2 PF04408.23 EGC32049.1 - 2.1e-21 76.2 0.0 2.1e-21 76.2 0.0 2.3 2 1 0 2 2 2 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGC32049.1 - 1.9e-14 53.9 0.0 4.3e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain OB_NTP_bind PF07717.16 EGC32049.1 - 1.2e-13 51.2 0.4 3e-13 49.9 0.0 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Allexi_40kDa PF05549.11 EGC32049.1 - 0.0019 17.7 0.2 0.0043 16.6 0.2 1.6 1 0 0 1 1 1 1 Allexivirus 40kDa protein Lipoprotein_2 PF00921.17 EGC32049.1 - 0.0069 16.0 7.5 0.011 15.3 7.5 1.2 1 0 0 1 1 1 1 Borrelia lipoprotein P4Ha_N PF08336.11 EGC32049.1 - 0.071 13.1 1.2 0.18 11.8 1.2 1.7 1 0 0 1 1 1 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Pyridoxal_deC PF00282.19 EGC32051.1 - 1.2e-75 254.6 0.0 1.5e-75 254.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain OTU PF02338.19 EGC32052.1 - 2e-09 38.0 0.1 2.5e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease NAT PF04768.13 EGC32053.1 - 1e-34 119.7 0.0 2.8e-34 118.2 0.0 1.7 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase AA_kinase PF00696.28 EGC32053.1 - 9e-07 28.7 0.1 5.5e-06 26.2 0.1 2.4 1 1 0 1 1 1 1 Amino acid kinase family VID27 PF08553.10 EGC32054.1 - 6e-88 295.3 2.9 5.2e-87 292.2 2.9 2.1 1 1 0 1 1 1 1 VID27 C-terminal WD40-like domain VID27_PH PF17747.1 EGC32054.1 - 1.3e-09 38.3 5.8 5.4e-09 36.3 1.5 2.7 2 0 0 2 2 2 1 VID27 PH-like domain BUD22 PF09073.10 EGC32054.1 - 0.14 11.5 64.5 0.043 13.2 52.8 2.5 2 0 0 2 2 2 0 BUD22 DUF572 PF04502.13 EGC32054.1 - 1.6 8.3 43.9 1.5 8.4 34.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF572) MMgT PF10270.9 EGC32055.1 - 1.3e-11 44.8 0.0 1.5e-11 44.5 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter LANC_like PF05147.13 EGC32055.1 - 0.11 11.0 0.0 0.19 10.2 0.0 1.3 1 1 0 1 1 1 0 Lanthionine synthetase C-like protein Guanylate_cyc PF00211.20 EGC32056.1 - 2.9e-60 203.1 0.1 5.6e-60 202.1 0.1 1.5 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.13 EGC32056.1 - 4e-16 59.5 0.0 6.2e-16 58.9 0.0 1.2 1 0 0 1 1 1 1 CHASE domain ASFV_J13L PF05568.11 EGC32056.1 - 0.038 13.7 0.4 0.088 12.6 0.4 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein CxC5 PF18718.1 EGC32056.1 - 0.055 13.5 0.4 0.16 12.0 0.4 1.8 1 0 0 1 1 1 0 CxC5 like cysteine cluster associated with KDZ transposases LapA_dom PF06305.11 EGC32056.1 - 0.087 12.6 0.0 1.9 8.4 0.0 2.4 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain DUF2976 PF11190.8 EGC32056.1 - 0.21 11.4 0.1 0.21 11.4 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) DUF4199 PF13858.6 EGC32056.1 - 2.2 8.7 7.7 1.9 8.9 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4199) Dickkopf_N PF04706.12 EGC32057.1 - 0.00081 19.8 33.8 0.0043 17.5 14.4 8.5 3 3 4 7 7 7 5 Dickkopf N-terminal cysteine-rich region ABC2_membrane_3 PF12698.7 EGC32058.1 - 7.3e-57 193.0 69.9 3.8e-33 115.0 32.3 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGC32058.1 - 2.1e-54 183.8 0.1 1e-26 94.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC32058.1 - 1.6e-18 67.6 0.2 2.7e-07 30.7 0.0 4.8 3 1 0 4 4 4 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC32058.1 - 6.4e-05 22.5 0.0 2.2 7.7 0.0 3.8 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC32058.1 - 0.00088 19.0 1.6 0.076 12.8 0.1 2.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain SRP54 PF00448.22 EGC32058.1 - 0.0023 17.6 1.5 1.5 8.4 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EGC32058.1 - 0.0028 18.2 4.7 0.62 10.5 0.2 2.8 2 0 0 2 2 2 2 AAA domain RsgA_GTPase PF03193.16 EGC32058.1 - 0.027 14.4 0.5 1.8 8.4 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase SbcCD_C PF13558.6 EGC32058.1 - 0.048 13.9 0.0 2.9 8.2 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_30 PF13604.6 EGC32058.1 - 0.15 11.8 0.3 6.4 6.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain SAC3_GANP PF03399.16 EGC32059.1 - 2.4e-92 309.5 1.2 2.4e-92 309.5 1.2 2.6 3 0 0 3 3 3 1 SAC3/GANP family Nup35_RRM_2 PF14605.6 EGC32059.1 - 0.047 13.7 0.0 0.12 12.4 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif BB_PF PF18063.1 EGC32060.1 - 1.3e-51 175.2 5.3 2.5e-51 174.2 5.3 1.5 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Ribosomal_S10 PF00338.22 EGC32060.1 - 0.0091 16.2 0.0 0.018 15.3 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e ILEI PF15711.5 EGC32060.1 - 0.017 15.6 0.3 0.038 14.5 0.3 1.7 1 0 0 1 1 1 0 Interleukin-like EMT inducer Dynein_light PF01221.18 EGC32061.1 - 2.2e-33 114.4 1.2 2.4e-33 114.3 1.2 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 Ground-like PF04155.18 EGC32061.1 - 0.0092 16.6 0.1 0.011 16.4 0.1 1.2 1 0 0 1 1 1 1 Ground-like domain PAD_porph PF04371.15 EGC32061.1 - 0.013 14.8 0.0 0.017 14.4 0.0 1.1 1 0 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase Ectatomin PF06457.11 EGC32061.1 - 0.16 11.9 0.4 0.27 11.2 0.4 1.4 1 0 0 1 1 1 0 Ectatomin tRNA-synt_1b PF00579.25 EGC32062.1 - 4e-73 246.3 2.2 5e-73 246.0 2.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-CDGSH PF09360.10 EGC32063.1 - 6.5e-06 26.3 12.6 0.0011 19.1 0.3 3.1 3 1 0 3 3 3 2 Iron-binding zinc finger CDGSH type Pur_ac_phosph_N PF16656.5 EGC32063.1 - 0.0085 16.6 0.5 0.013 16.1 0.5 1.5 1 1 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain GT-D PF08759.11 EGC32064.1 - 0.022 14.4 2.0 0.069 12.8 2.0 1.8 1 0 0 1 1 1 0 Glycosyltransferase GT-D fold DUF2654 PF10849.8 EGC32064.1 - 0.059 13.6 0.1 2.8 8.2 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2654) V-ATPase_H_N PF03224.14 EGC32065.1 - 1.9e-75 254.1 2.2 1.9e-75 254.1 2.2 1.8 3 0 0 3 3 3 1 V-ATPase subunit H V-ATPase_H_C PF11698.8 EGC32065.1 - 1.1e-43 148.1 3.9 5.4e-42 142.6 0.4 3.4 3 1 1 4 4 4 1 V-ATPase subunit H HEAT_2 PF13646.6 EGC32065.1 - 0.00063 20.1 0.0 0.79 10.2 0.0 2.7 2 0 0 2 2 2 2 HEAT repeats Arm PF00514.23 EGC32065.1 - 0.0041 17.1 0.3 5.9 7.1 0.0 3.2 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat NopRA1 PF16201.5 EGC32065.1 - 0.02 14.5 0.1 0.42 10.1 0.0 2.8 3 1 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 Pico_P2B PF01552.17 EGC32065.1 - 0.055 13.6 1.6 12 6.1 0.1 3.4 3 0 0 3 3 3 0 Picornavirus 2B protein Arm_2 PF04826.13 EGC32065.1 - 0.48 9.8 0.0 0.48 9.8 0.0 3.0 4 0 0 4 4 4 0 Armadillo-like Prp18 PF02840.15 EGC32066.1 - 7.9e-63 210.8 0.2 7.9e-63 210.8 0.2 3.1 3 1 0 3 3 3 1 Prp18 domain PRP4 PF08799.11 EGC32066.1 - 2.8e-14 52.4 0.2 4.7e-14 51.6 0.2 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like BLM10_mid PF16507.5 EGC32066.1 - 0.0007 18.4 3.0 0.0012 17.6 3.0 1.3 1 0 0 1 1 1 1 Proteasome-substrate-size regulator, mid region Homeodomain PF00046.29 EGC32067.1 - 1.5e-10 40.7 4.7 1.5e-10 40.7 0.5 3.0 3 0 0 3 3 3 1 Homeodomain Cyclin_N PF00134.23 EGC32067.1 - 2.2e-09 37.1 0.5 2.2e-09 37.1 0.5 3.8 4 0 0 4 4 4 1 Cyclin, N-terminal domain Homeobox_KN PF05920.11 EGC32067.1 - 0.023 14.6 0.9 0.17 11.8 0.2 2.9 2 0 0 2 2 2 0 Homeobox KN domain 7tm_3 PF00003.22 EGC32068.1 - 2.8e-33 115.6 37.4 6.5e-33 114.4 37.4 1.6 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Wzy_C PF04932.15 EGC32068.1 - 0.8 9.3 0.0 0.8 9.3 0.0 4.0 3 1 0 3 3 3 0 O-Antigen ligase Cytochrom_B_C PF00032.17 EGC32068.1 - 9.1 6.6 16.6 0.62 10.4 2.8 3.2 2 1 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD RhoGAP PF00620.27 EGC32069.1 - 1.7e-33 115.6 0.1 3.7e-33 114.5 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.11 EGC32069.1 - 0.0032 17.5 4.4 8.3 7.0 0.0 5.7 6 1 0 6 6 6 1 Two component regulator propeller SapB_1 PF05184.15 EGC32070.1 - 1.3e-53 178.5 43.7 5.1e-12 45.6 1.3 7.6 8 0 0 8 8 8 5 Saposin-like type B, region 1 SapB_2 PF03489.17 EGC32070.1 - 2e-51 171.8 37.8 1.5e-10 41.0 1.1 7.8 8 0 0 8 8 8 5 Saposin-like type B, region 2 zf-Mss51 PF13824.6 EGC32070.1 - 6.8e-05 22.9 1.3 6.6 6.9 0.0 4.7 4 0 0 4 4 4 2 Zinc-finger of mitochondrial splicing suppressor 51 Phytoreo_Pns PF05451.11 EGC32070.1 - 7e-05 22.1 0.1 1.8 7.6 0.0 3.2 3 0 0 3 3 3 2 Phytoreovirus nonstructural protein Pns10/11 Importin_rep_3 PF18806.1 EGC32070.1 - 9.8e-05 22.3 0.0 2.8 8.1 0.0 4.1 4 0 0 4 4 4 1 Importin 13 repeat DUF1242 PF06842.12 EGC32070.1 - 0.00024 20.8 0.1 6.1 6.7 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1242) CNV-Replicase_N PF16688.5 EGC32070.1 - 0.00063 20.0 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 2 Replicase polyprotein N-term from Coronavirus nsp1 DUF445 PF04286.12 EGC32070.1 - 0.0023 17.8 0.0 3.7 7.3 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF445) DUF1677 PF07911.13 EGC32070.1 - 0.005 17.2 0.0 55 4.2 0.0 4.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1677) zf-H2C2_2 PF13465.6 EGC32070.1 - 0.0076 16.6 9.1 14 6.3 0.1 4.8 4 0 0 4 4 4 0 Zinc-finger double domain DUF3361 PF11841.8 EGC32070.1 - 0.015 15.2 5.4 2.5 8.0 0.0 3.8 4 1 1 5 5 5 0 Domain of unknown function (DUF3361) DUF4800 PF16057.5 EGC32070.1 - 0.022 14.0 2.9 6.7 5.9 0.1 3.5 4 0 0 4 4 4 0 Domain of unknown function (DUF4800) Staphostatin_A PF09022.10 EGC32070.1 - 0.12 12.3 16.7 32 4.5 0.0 5.8 5 1 1 6 6 6 0 Staphostatin A FANCI_S1 PF14675.6 EGC32070.1 - 0.19 11.3 3.4 0.4 10.2 0.1 3.2 4 1 1 5 5 5 0 FANCI solenoid 1 Rubis-subs-bind PF09273.11 EGC32070.1 - 0.53 11.0 4.2 59 4.4 0.1 4.0 4 0 0 4 4 4 0 Rubisco LSMT substrate-binding RAI16-like PF10257.9 EGC32070.1 - 0.54 9.1 9.9 13 4.5 0.1 4.3 5 0 0 5 5 5 0 Retinoic acid induced 16-like protein Zn-C2H2_12 PF18112.1 EGC32070.1 - 2.7 8.6 7.6 68 4.1 0.1 4.0 3 0 0 3 3 3 0 Autophagy receptor zinc finger-C2H2 domain DUF2465 PF10239.9 EGC32070.1 - 3.6 6.7 8.4 9.5 5.3 1.7 3.5 2 1 2 4 4 4 0 Protein of unknown function (DUF2465) UQ_con PF00179.26 EGC32071.1 - 2.1e-45 153.8 0.5 2.4e-45 153.6 0.5 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC32071.1 - 0.00086 19.6 0.8 0.0011 19.3 0.8 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGC32071.1 - 0.034 13.9 0.0 0.042 13.6 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B 2Fe-2S_thioredx PF01257.19 EGC32072.1 - 2.3e-59 199.4 0.3 2.8e-59 199.1 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin FNIP PF05725.12 EGC32073.1 - 1.6e-32 111.4 57.3 0.00012 22.2 0.2 10.9 5 2 7 13 13 13 11 FNIP Repeat zf-B_box PF00643.24 EGC32073.1 - 8.9e-05 22.6 5.6 0.00015 21.8 5.6 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC32073.1 - 0.22 11.7 2.7 0.51 10.5 2.7 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) G8 PF10162.9 EGC32074.1 - 2.9e-28 98.4 0.0 9.8e-28 96.7 0.0 2.0 1 0 0 1 1 1 1 G8 domain Amnionless PF14828.6 EGC32074.1 - 0.016 14.1 0.2 0.048 12.5 0.0 1.7 2 0 0 2 2 2 0 Amnionless Sec1 PF00995.23 EGC32075.1 - 5e-103 346.3 0.3 6.1e-103 346.0 0.3 1.1 1 0 0 1 1 1 1 Sec1 family NAD_binding_6 PF08030.12 EGC32075.1 - 0.008 16.3 0.5 0.019 15.1 0.5 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Paramyxo_P PF01806.17 EGC32075.1 - 0.021 14.2 0.3 0.037 13.5 0.3 1.3 1 0 0 1 1 1 0 Paramyxovirinae P phosphoprotein C-terminal region RhoGAP PF00620.27 EGC32076.1 - 1.8e-27 96.1 0.2 1.5e-26 93.1 0.1 2.4 2 0 0 2 2 2 1 RhoGAP domain Cyanate_lyase PF02560.14 EGC32076.1 - 0.2 11.5 0.1 2.8 7.9 0.1 2.2 2 0 0 2 2 2 0 Cyanate lyase C-terminal domain Presenilin PF01080.17 EGC32076.1 - 0.46 9.2 1.2 0.59 8.8 1.2 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGC32076.1 - 2.1 9.4 4.4 4.3 8.3 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4611 PF15387.6 EGC32076.1 - 3.9 7.8 7.8 12 6.2 7.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) PBP1_TM PF14812.6 EGC32076.1 - 6.5 7.2 6.3 13 6.2 6.3 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4637 PF15470.6 EGC32076.1 - 6.6 6.4 7.5 12 5.6 7.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Inhibitor_I36 PF03995.13 EGC32077.1 - 1.5e-06 28.0 0.4 2.1e-06 27.5 0.4 1.4 1 1 0 1 1 1 1 Peptidase inhibitor family I36 L_protein_N PF15518.6 EGC32077.1 - 0.039 13.8 0.1 0.095 12.6 0.0 1.6 1 1 0 1 1 1 0 L protein N-terminus Misat_Tub_SegII PF10644.9 EGC32078.1 - 1.3e-30 106.1 3.1 1.3e-30 106.1 3.1 2.8 3 0 0 3 3 3 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGC32078.1 - 1.3e-16 60.8 0.6 3.2e-16 59.5 0.6 1.6 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.25 EGC32078.1 - 0.00013 22.2 11.4 0.025 14.8 0.0 3.1 3 0 0 3 3 3 2 Tubulin/FtsZ family, GTPase domain AIM24 PF01987.17 EGC32079.1 - 1.7e-57 194.4 3.2 3.3e-57 193.5 2.4 1.7 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 Abhydrolase_1 PF00561.20 EGC32080.1 - 8.9e-07 28.8 0.0 1.3e-05 25.0 0.0 2.2 1 1 1 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC32080.1 - 4.8e-06 26.0 0.0 0.0013 18.1 0.0 2.4 2 0 0 2 2 2 2 Serine aminopeptidase, S33 SAM_2 PF07647.17 EGC32080.1 - 4.9e-06 26.6 0.2 9.8e-06 25.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_S9 PF00326.21 EGC32080.1 - 8.3e-06 25.4 0.1 0.00014 21.5 0.1 2.2 1 1 0 1 1 1 1 Prolyl oligopeptidase family SAM_1 PF00536.30 EGC32080.1 - 1.1e-05 25.7 0.2 3.3e-05 24.3 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) BAAT_C PF08840.11 EGC32080.1 - 0.0038 17.2 0.4 0.024 14.6 0.4 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Ser_hydrolase PF06821.13 EGC32080.1 - 0.0057 16.5 0.0 0.034 14.0 0.0 2.0 1 1 0 1 1 1 1 Serine hydrolase Abhydrolase_2 PF02230.16 EGC32080.1 - 0.02 14.7 5.7 0.05 13.4 0.0 2.6 2 1 0 3 3 3 0 Phospholipase/Carboxylesterase DUF5125 PF17163.4 EGC32080.1 - 0.025 14.7 0.1 0.056 13.6 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5125) FSH1 PF03959.13 EGC32080.1 - 0.033 13.9 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) DUF1749 PF08538.10 EGC32080.1 - 0.033 13.3 0.2 0.21 10.7 0.0 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1749) DLH PF01738.18 EGC32080.1 - 0.039 13.5 0.0 0.072 12.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EGC32080.1 - 0.049 13.4 0.0 0.27 11.0 0.0 2.1 1 1 0 2 2 2 0 Alpha/beta hydrolase family IncFII_repA PF02387.15 EGC32080.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 IncFII RepA protein family NCD1 PF04904.13 EGC32080.1 - 0.14 12.2 0.1 0.34 10.9 0.1 1.6 1 0 0 1 1 1 0 NAB conserved region 1 (NCD1) Herpes_capsid PF06112.11 EGC32080.1 - 5.3 7.1 16.8 9.3 6.3 16.8 1.4 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.9 EGC32080.1 - 6.7 5.1 13.8 8.5 4.8 13.8 1.1 1 0 0 1 1 1 0 Macoilin family Tetraspanin PF00335.20 EGC32081.1 - 2.2e-15 57.0 7.7 3.6e-15 56.3 7.7 1.3 1 1 0 1 1 1 1 Tetraspanin family DUF2306 PF10067.9 EGC32081.1 - 0.00034 20.9 2.8 0.00034 20.9 2.8 1.6 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) UPF0093 PF03653.13 EGC32081.1 - 0.022 15.0 4.1 0.045 14.0 4.1 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0093) DUF420 PF04238.12 EGC32081.1 - 0.13 12.6 8.4 0.055 13.8 3.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF420) FixQ PF05545.11 EGC32081.1 - 3.3 7.7 6.9 4.7 7.3 0.0 3.4 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ DUF2981 PF11200.8 EGC32081.1 - 4.6 6.9 10.6 7.3 6.2 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) DUF1706 PF08020.11 EGC32082.1 - 0.0042 17.0 2.1 0.0073 16.2 0.3 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1706) DUF4038 PF13204.6 EGC32082.1 - 0.27 10.8 3.6 0.22 11.1 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4038) Homeobox_KN PF05920.11 EGC32083.1 - 1.3e-14 53.7 0.1 1.8e-14 53.4 0.1 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGC32083.1 - 2.7e-12 46.3 0.1 3e-12 46.2 0.1 1.0 1 0 0 1 1 1 1 Homeodomain DUF2963 PF11178.8 EGC32084.1 - 0.043 13.5 4.4 64 3.4 0.0 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2963) FNIP PF05725.12 EGC32085.1 - 8.7e-120 390.7 50.1 2.9e-16 59.3 0.1 9.1 9 0 0 9 9 9 9 FNIP Repeat Cdh1_DBD_1 PF18196.1 EGC32085.1 - 0.064 13.6 0.2 2.1e+02 2.2 0.0 6.1 4 3 6 11 11 11 0 Chromodomain helicase DNA-binding domain 1 Fz PF01392.22 EGC32086.1 - 0.00068 20.2 6.3 0.00068 20.2 6.3 1.8 2 0 0 2 2 2 1 Fz domain Nodulin_late PF07127.11 EGC32086.1 - 0.17 12.2 1.6 5.7 7.4 0.3 3.6 2 0 0 2 2 2 0 Late nodulin protein DUF1980 PF09323.10 EGC32086.1 - 0.32 10.9 9.4 2.9 7.8 1.1 3.2 3 1 0 3 3 3 0 Domain of unknown function (DUF1980) 2-Hacid_dh_C PF02826.19 EGC32087.1 - 8.1e-51 171.9 0.0 1.2e-50 171.3 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC32087.1 - 1.2e-29 102.7 0.0 1.4e-29 102.5 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC32087.1 - 9.5e-08 32.4 0.0 1.8e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EGC32087.1 - 0.00011 23.0 0.0 0.048 14.5 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold DUF99 PF01949.16 EGC32087.1 - 0.035 13.5 0.0 0.062 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function DUF99 AlaDh_PNT_N PF05222.15 EGC32087.1 - 0.097 13.0 0.0 1.6 9.0 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain UDPG_MGDP_dh_C PF03720.15 EGC32087.1 - 0.11 13.0 0.0 0.44 11.0 0.0 1.9 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain AIRC PF00731.20 EGC32087.1 - 0.17 11.5 0.0 0.36 10.4 0.0 1.5 1 0 0 1 1 1 0 AIR carboxylase Semialdhyde_dh PF01118.24 EGC32087.1 - 0.17 12.3 0.2 14 6.2 0.1 2.6 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain RRM_1 PF00076.22 EGC32088.1 - 8.1e-11 41.6 0.4 1.5e-10 40.8 0.4 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Torus PF16131.5 EGC32088.1 - 4.3e-07 30.6 0.1 4.3e-07 30.6 0.1 2.2 2 0 0 2 2 2 1 Torus domain RRM_5 PF13893.6 EGC32088.1 - 1.9e-06 27.5 0.1 3.3e-06 26.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf_CCCH_4 PF18345.1 EGC32088.1 - 1.9e-06 27.7 3.5 4.4e-06 26.6 3.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGC32088.1 - 4.7e-05 23.2 2.8 4.7e-05 23.2 2.8 2.2 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGC32088.1 - 8.6e-05 22.7 0.8 0.0004 20.6 0.0 2.3 2 1 0 2 2 2 1 Zinc-finger containing family RRM_occluded PF16842.5 EGC32088.1 - 0.00058 19.7 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Occluded RNA-recognition motif zf-CCCH_2 PF14608.6 EGC32088.1 - 0.0011 19.4 2.7 0.0029 18.0 2.7 1.8 1 0 0 1 1 1 1 RNA-binding, Nab2-type zinc finger RRM_3 PF08777.11 EGC32088.1 - 0.0028 17.7 0.9 0.0078 16.2 0.9 1.8 1 1 0 1 1 1 1 RNA binding motif FYVE PF01363.21 EGC32088.1 - 0.0064 16.6 0.8 0.015 15.4 0.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger zf-CCCH_4 PF18044.1 EGC32088.1 - 0.0065 16.3 2.8 0.013 15.3 2.8 1.5 1 0 0 1 1 1 1 CCCH-type zinc finger RNA_bind PF08675.11 EGC32088.1 - 0.026 14.5 0.2 0.066 13.2 0.0 1.7 2 0 0 2 2 1 0 RNA binding domain DUF4834 PF16118.5 EGC32088.1 - 0.71 10.9 5.0 2.3 9.2 5.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3464 PF11947.8 EGC32088.1 - 7.9 6.2 9.4 12 5.7 7.4 2.0 2 0 0 2 2 2 0 Photosynthesis affected mutant 68 PQ-loop PF04193.14 EGC32090.1 - 6.8e-22 77.0 15.7 1.4e-16 60.0 0.6 3.6 4 0 0 4 4 4 2 PQ loop repeat Intg_mem_TP0381 PF09529.10 EGC32090.1 - 9e-05 22.1 13.8 0.00011 21.8 13.3 1.3 1 1 0 1 1 1 1 Integral membrane protein (intg_mem_TP0381) DUF4149 PF13664.6 EGC32090.1 - 0.2 12.0 13.6 2.2 8.6 0.6 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) TssN PF17555.2 EGC32090.1 - 0.58 9.5 17.6 1 8.7 17.6 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN Rho_GDI PF02115.17 EGC32091.1 - 1.4e-54 184.8 0.4 1.6e-54 184.7 0.4 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Proteasome PF00227.26 EGC32092.1 - 1e-51 175.1 0.0 1.5e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC32092.1 - 6.9e-13 48.0 0.2 1.2e-12 47.3 0.2 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DMPK_coil PF08826.10 EGC32092.1 - 0.22 11.7 1.6 1.4 9.0 0.1 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like HA2 PF04408.23 EGC32093.1 - 6.6e-27 93.9 0.1 6.6e-27 93.9 0.1 2.9 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC32093.1 - 7.9e-24 83.8 0.0 2.2e-23 82.4 0.0 1.8 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.23 EGC32093.1 - 9.6e-08 32.3 0.2 9.6e-08 32.3 0.2 2.4 3 0 0 3 3 3 1 S1 RNA binding domain HAD_2 PF13419.6 EGC32093.1 - 0.073 13.2 1.2 0.21 11.6 0.6 2.0 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DAG_kinase_N PF14513.6 EGC32093.1 - 0.081 13.1 4.5 0.06 13.5 1.1 2.4 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus NRIP1_repr_1 PF15687.5 EGC32093.1 - 0.27 10.9 4.9 0.3 10.7 1.0 2.3 2 0 0 2 2 2 0 Nuclear receptor-interacting protein 1 repression 1 Robl_LC7 PF03259.17 EGC32095.1 - 0.00092 18.9 0.0 0.0013 18.5 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain FNIP PF05725.12 EGC32096.1 - 5.4e-90 295.4 81.4 6.8e-13 48.6 0.6 9.7 3 2 6 11 11 11 11 FNIP Repeat GCV_T_C PF08669.11 EGC32096.1 - 0.058 13.3 0.0 3.4 7.7 0.0 3.0 3 0 0 3 3 3 0 Glycine cleavage T-protein C-terminal barrel domain Curto_V2 PF07325.11 EGC32098.1 - 0.35 10.8 6.9 2.4 8.0 1.3 3.0 2 0 0 2 2 2 0 Curtovirus V2 protein SET PF00856.28 EGC32099.1 - 1.1e-15 58.4 18.6 1.1e-15 58.4 18.6 3.2 2 2 0 2 2 2 1 SET domain TPR_2 PF07719.17 EGC32099.1 - 9.1e-06 25.4 0.4 0.044 13.9 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32099.1 - 0.0087 15.9 5.5 0.013 15.3 0.4 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Otopetrin PF03189.13 EGC32099.1 - 0.018 13.9 5.0 0.074 11.8 3.7 2.0 1 1 1 2 2 2 0 Otopetrin CDC45 PF02724.14 EGC32099.1 - 0.12 10.6 24.0 0.15 10.3 8.2 2.2 2 0 0 2 2 2 0 CDC45-like protein TPR_12 PF13424.6 EGC32099.1 - 0.2 11.9 0.1 3.8 7.9 0.1 2.2 1 1 1 2 2 2 0 Tetratricopeptide repeat DZR PF12773.7 EGC32099.1 - 1.2 9.2 19.8 0.26 11.3 1.8 3.5 2 1 1 3 3 3 0 Double zinc ribbon DDHD PF02862.17 EGC32099.1 - 1.6 8.8 20.7 1.3 9.1 2.1 2.5 2 0 0 2 2 2 0 DDHD domain Gti1_Pac2 PF09729.9 EGC32099.1 - 3.3 7.8 32.9 3 7.9 13.3 2.5 2 0 0 2 2 2 0 Gti1/Pac2 family Nop14 PF04147.12 EGC32099.1 - 3.3 5.8 26.6 0.56 8.4 12.9 2.2 2 0 0 2 2 2 0 Nop14-like family FNIP PF05725.12 EGC32100.1 - 1.1e-103 339.2 39.9 2e-15 56.6 0.3 8.3 8 0 0 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 EGC32100.1 - 0.029 14.3 5.5 0.088 12.8 0.2 3.7 2 1 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EGC32100.1 - 3.8 8.4 9.4 28 5.8 0.3 6.3 4 2 0 4 4 4 0 Leucine Rich Repeat ATP-synt_8 PF00895.20 EGC32101.1 - 0.033 14.7 2.9 0.033 14.7 2.9 4.3 3 1 1 4 4 4 0 ATP synthase protein 8 SPX PF03105.19 EGC32102.1 - 1.4 8.8 26.4 1.1 9.1 16.4 2.9 3 0 0 3 3 3 0 SPX domain Ndc1_Nup PF09531.10 EGC32102.1 - 7.2 5.2 15.4 17 3.9 15.4 1.6 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Maf PF02545.14 EGC32104.1 - 1.3e-45 155.2 0.0 1.5e-45 155.0 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GTP_EFTU PF00009.27 EGC32105.1 - 2.2e-29 102.4 0.0 3.5e-29 101.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGC32105.1 - 1.1e-12 47.8 0.0 2.2e-12 46.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_IV PF03764.18 EGC32105.1 - 2.9e-11 43.2 0.0 5.9e-11 42.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGC32105.1 - 2e-07 31.0 0.0 5.5e-07 29.6 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.23 EGC32105.1 - 1e-06 28.8 0.2 2.4e-06 27.6 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC32105.1 - 1.3e-05 24.7 0.1 2.7e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D2 PF03144.25 EGC32105.1 - 0.0049 17.2 0.0 0.02 15.3 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 TniB PF05621.11 EGC32105.1 - 0.0073 15.7 0.0 0.013 15.0 0.0 1.3 1 0 0 1 1 1 1 Bacterial TniB protein Septin PF00735.18 EGC32105.1 - 0.073 12.3 0.4 0.15 11.3 0.4 1.4 1 0 0 1 1 1 0 Septin FeoB_N PF02421.18 EGC32105.1 - 0.11 12.0 0.9 0.47 10.0 0.9 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B RNA_pol PF00940.19 EGC32106.1 - 6.4e-167 555.6 0.0 3.2e-166 553.3 0.0 2.1 2 1 0 2 2 2 1 DNA-dependent RNA polymerase RPOL_N PF14700.6 EGC32106.1 - 1.7e-27 96.7 0.1 5.7e-22 78.5 0.0 2.3 2 0 0 2 2 2 2 DNA-directed RNA polymerase N-terminal FAM177 PF14774.6 EGC32107.1 - 3.4e-16 59.7 10.0 4.7e-16 59.2 10.0 1.2 1 0 0 1 1 1 1 FAM177 family FAM221 PF14753.6 EGC32107.1 - 0.0063 16.1 0.8 0.0086 15.7 0.8 1.2 1 0 0 1 1 1 1 Protein FAM221A/B Opi1 PF08618.10 EGC32107.1 - 0.01 15.1 1.3 0.011 15.0 1.3 1.2 1 0 0 1 1 1 0 Transcription factor Opi1 DUF1178 PF06676.11 EGC32107.1 - 0.014 15.8 5.9 0.019 15.3 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1178) DUF3292 PF11696.8 EGC32107.1 - 0.08 11.3 4.5 0.085 11.2 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) FPN1 PF06963.12 EGC32107.1 - 0.13 10.8 0.4 0.18 10.3 0.4 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) CbtA PF09490.10 EGC32107.1 - 0.2 11.4 0.0 0.26 11.0 0.0 1.1 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) Slu7 PF11708.8 EGC32107.1 - 0.74 9.5 19.0 0.27 11.0 1.9 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing Prp18-interacting factor PH_BEACH PF14844.6 EGC32107.1 - 1.7 8.8 6.2 0.63 10.2 3.1 1.9 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH FixO PF02433.15 EGC32107.1 - 1.8 7.9 8.2 0.35 10.3 4.7 1.5 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO Ctr PF04145.15 EGC32107.1 - 2.2 8.9 8.1 17 6.0 5.4 2.1 1 1 1 2 2 2 0 Ctr copper transporter family DUF2956 PF11169.8 EGC32107.1 - 7.3 6.8 19.5 9.7 6.4 1.9 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2956) DUF1899 PF08953.11 EGC32108.1 - 1.7e-31 107.8 1.0 4.2e-31 106.6 0.5 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1899) WD40_4 PF16300.5 EGC32108.1 - 1e-20 73.3 0.4 1.7e-20 72.6 0.4 1.4 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGC32108.1 - 3.2e-14 53.1 3.9 0.00046 20.9 0.2 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32108.1 - 0.0035 17.6 0.3 0.73 10.2 0.0 3.6 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC32108.1 - 0.026 13.5 0.0 2.9 6.8 0.0 3.0 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Asn_synthase PF00733.21 EGC32110.1 - 3.6e-69 234.1 0.0 4.4e-69 233.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGC32110.1 - 2.1e-47 160.1 0.0 3.8e-47 159.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC32110.1 - 8.4e-37 126.4 0.0 1.4e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC32110.1 - 3.5e-05 23.4 0.0 7.8e-05 22.2 0.0 1.6 1 1 0 1 1 1 1 Aluminium induced protein Erf4 PF10256.9 EGC32111.1 - 2.8e-05 24.2 0.8 0.00017 21.7 0.8 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family HDAC4_Gln PF12203.8 EGC32112.1 - 0.0064 16.6 3.8 0.011 15.9 3.8 1.4 1 0 0 1 1 1 1 Glutamine rich N terminal domain of histone deacetylase 4 YpsA PF06908.11 EGC32112.1 - 0.0084 16.1 5.5 0.017 15.2 5.4 1.6 1 1 0 1 1 1 1 YspA SLOG family Pkinase PF00069.25 EGC32113.1 - 1.4e-73 247.5 0.0 1.7e-73 247.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32113.1 - 8.4e-37 126.9 0.0 1.1e-36 126.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGC32113.1 - 1.6e-21 76.8 0.2 3.4e-21 75.7 0.2 1.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC32113.1 - 1.1e-08 35.4 0.9 1.4e-07 31.9 0.9 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGC32113.1 - 2.7e-06 27.4 0.0 6.6e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 PH domain Pkinase_C PF00433.24 EGC32113.1 - 3.7e-06 27.6 0.3 8e-06 26.5 0.1 1.7 2 0 0 2 2 1 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGC32113.1 - 0.00016 21.1 0.1 0.0063 15.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like PH_8 PF15409.6 EGC32113.1 - 0.00045 20.4 1.5 0.002 18.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.6 EGC32113.1 - 0.03 14.7 0.7 0.18 12.2 0.0 2.5 2 2 0 2 2 2 0 Pleckstrin homology domain FTA2 PF13095.6 EGC32113.1 - 0.037 13.6 0.1 1.4 8.5 0.1 2.2 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGC32113.1 - 0.071 12.5 0.0 0.55 9.6 0.0 2.0 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC32113.1 - 0.074 13.0 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF3791 PF12668.7 EGC32113.1 - 0.35 11.0 1.9 0.37 10.9 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) Ribosomal_L1 PF00687.21 EGC32114.1 - 3.4e-17 62.9 9.5 3.4e-17 62.9 9.5 2.9 2 2 1 3 3 3 1 Ribosomal protein L1p/L10e family CDC45 PF02724.14 EGC32114.1 - 0.0027 16.1 3.1 0.0033 15.8 3.1 1.2 1 0 0 1 1 1 1 CDC45-like protein PBP1_TM PF14812.6 EGC32114.1 - 0.16 12.4 8.2 0.44 10.9 8.2 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PTPRCAP PF15713.5 EGC32114.1 - 5.4 7.3 9.6 12 6.2 9.6 1.6 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated Beta-lactamase2 PF13354.6 EGC32115.1 - 9.7e-26 90.6 0.0 1.4e-24 86.8 0.0 2.0 1 1 0 1 1 1 1 Beta-lactamase enzyme family DPBB_1 PF03330.18 EGC32116.1 - 2e-11 44.0 0.6 1.4e-10 41.3 0.6 2.1 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGC32116.1 - 0.0011 18.8 0.2 0.013 15.4 0.1 2.2 2 0 0 2 2 2 1 Barwin family Pollen_allerg_1 PF01357.21 EGC32116.1 - 0.0013 18.7 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 Pollen allergen Cerato-platanin PF07249.12 EGC32116.1 - 0.014 15.6 0.1 0.028 14.6 0.1 1.5 1 0 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.18 EGC32117.1 - 9.3e-08 32.3 0.1 6.9e-07 29.5 0.1 2.3 1 1 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EGC32117.1 - 0.00088 19.3 0.0 0.002 18.1 0.0 1.6 2 0 0 2 2 2 1 Pollen allergen Barwin PF00967.17 EGC32117.1 - 0.025 14.5 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 Barwin family ATP-synt_G PF04718.15 EGC32119.1 - 4.6e-05 24.2 0.0 4.9e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit SSP160 PF06933.11 EGC32120.1 - 0.048 11.9 8.8 0.057 11.6 8.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FTA4 PF13093.6 EGC32120.1 - 0.067 13.1 12.3 0.04 13.8 7.7 2.1 2 0 0 2 2 2 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF3439 PF11921.8 EGC32120.1 - 0.079 12.9 9.2 0.035 14.1 6.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC32120.1 - 0.096 12.7 12.7 0.13 12.3 12.7 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein Myb_DNA-binding PF00249.31 EGC32122.1 - 7.9e-29 99.6 8.2 9.2e-15 54.6 0.3 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC32122.1 - 2.6e-23 82.0 6.0 1.7e-15 57.0 1.1 2.7 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGC32122.1 - 1.1e-05 25.4 1.5 0.0062 16.5 0.6 2.5 1 1 1 2 2 2 2 SLIDE PHD PF00628.29 EGC32122.1 - 0.0017 18.2 17.5 0.0041 17.0 17.5 1.7 1 0 0 1 1 1 1 PHD-finger Myb_DNA-bind_7 PF15963.5 EGC32122.1 - 0.0063 16.4 4.6 0.1 12.5 0.0 3.0 2 1 1 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 EGC32122.1 - 0.12 12.5 5.4 0.56 10.3 1.8 2.4 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Nucleo_P87 PF07267.11 EGC32122.1 - 0.12 11.2 7.4 0.16 10.8 7.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF2052 PF09747.9 EGC32122.1 - 0.14 12.2 8.5 0.23 11.6 8.5 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TBX PF12598.8 EGC32122.1 - 0.15 12.9 13.1 0.29 11.9 13.1 1.6 1 0 0 1 1 1 0 T-box transcription factor Nop16 PF09420.10 EGC32122.1 - 0.3 11.1 11.4 0.028 14.5 6.8 1.6 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Ndc1_Nup PF09531.10 EGC32122.1 - 0.57 8.8 9.0 0.56 8.8 9.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FAM176 PF14851.6 EGC32122.1 - 0.86 9.3 7.4 1.6 8.4 7.4 1.5 1 0 0 1 1 1 0 FAM176 family CENP-B_dimeris PF09026.10 EGC32122.1 - 0.97 9.9 6.6 1.8 9.0 6.6 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Zip PF02535.22 EGC32122.1 - 1.9 7.6 5.5 2.1 7.5 5.5 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter TIMELESS PF04821.14 EGC32123.1 - 5.7e-51 173.4 10.3 5.7e-51 173.4 10.3 7.6 6 2 3 9 9 9 1 Timeless protein TIMELESS_C PF05029.13 EGC32123.1 - 1.2e-11 44.5 1.3 1.2e-11 44.5 1.3 7.9 4 1 5 10 10 10 2 Timeless protein C terminal region PAT1 PF09770.9 EGC32125.1 - 0.12 10.6 21.7 0.12 10.6 21.7 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DDRGK PF09756.9 EGC32125.1 - 1.6 8.3 11.8 2.5 7.6 11.8 1.3 1 0 0 1 1 1 0 DDRGK domain Pex14_N PF04695.13 EGC32125.1 - 4 8.1 33.1 1.2 9.7 28.5 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Bromodomain PF00439.25 EGC32127.1 - 3.4e-27 94.3 1.2 1.2e-26 92.5 1.2 2.1 1 0 0 1 1 1 1 Bromodomain BET PF17035.5 EGC32127.1 - 1.8e-11 44.1 5.8 1.8e-11 44.1 5.8 3.3 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation BTB PF00651.31 EGC32127.1 - 2.1e-09 37.6 0.9 2.1e-09 37.6 0.9 2.9 3 0 0 3 3 3 1 BTB/POZ domain ORC6 PF05460.13 EGC32127.1 - 0.053 12.8 32.2 0.053 12.8 12.4 2.6 3 0 0 3 3 3 0 Origin recognition complex subunit 6 (ORC6) SR-25 PF10500.9 EGC32127.1 - 1.4 8.5 36.4 1 8.9 19.9 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Pol_alpha_B_N PF08418.10 EGC32127.1 - 2.1 8.3 28.5 0.1 12.6 2.5 2.7 3 0 0 3 3 3 0 DNA polymerase alpha subunit B N-terminal Abi_C PF14355.6 EGC32128.1 - 2.9 8.0 4.9 2.9 8.0 2.0 2.2 2 1 0 2 2 2 0 Abortive infection C-terminus Stork_head PF10264.9 EGC32129.1 - 0.12 12.6 1.2 5.3 7.3 0.1 2.7 1 1 1 2 2 2 0 Winged helix Storkhead-box1 domain YL1 PF05764.13 EGC32131.1 - 8.5e-17 62.1 62.9 7.6e-10 39.3 41.7 3.7 2 2 1 3 3 3 2 YL1 nuclear protein YL1_C PF08265.11 EGC32131.1 - 1.3e-14 53.7 0.9 3.4e-14 52.3 0.1 2.0 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain Peptidase_S76 PF13611.6 EGC32131.1 - 0.025 14.9 1.7 0.096 13.0 1.7 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Arf PF00025.21 EGC32132.1 - 5.2e-61 205.1 0.2 5.6e-61 205.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC32132.1 - 1.1e-10 41.8 0.1 1.4e-10 41.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC32132.1 - 8.5e-10 38.4 0.0 1e-09 38.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC32132.1 - 2.6e-09 36.7 1.5 5.2e-08 32.4 0.8 2.2 1 1 1 2 2 2 1 G-protein alpha subunit Ras PF00071.22 EGC32132.1 - 4.6e-09 36.1 0.0 5.5e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGC32132.1 - 5.7e-09 35.7 0.1 6.9e-09 35.4 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC32132.1 - 7.9e-05 22.7 0.0 0.00018 21.5 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase zf-C2H2_assoc3 PF16637.5 EGC32132.1 - 0.19 11.9 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 Putative zinc-finger between two C2H2 zinc-fingers on Patz HJURP_C PF12347.8 EGC32132.1 - 0.21 11.7 0.1 0.4 10.8 0.1 1.4 1 0 0 1 1 1 0 Holliday junction regulator protein family C-terminal repeat PolyA_pol PF01743.20 EGC32133.1 - 1.5e-26 93.3 1.1 6.4e-26 91.2 0.2 2.2 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGC32133.1 - 0.00037 20.2 0.0 0.00083 19.1 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A G-patch PF01585.23 EGC32134.1 - 1.6e-08 34.3 1.3 4.5e-08 32.9 1.3 1.8 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGC32134.1 - 0.0064 16.6 0.9 0.0064 16.6 0.9 7.0 5 1 0 5 5 5 1 G-patch domain ACR_tran PF00873.19 EGC32134.1 - 6.2 4.3 5.5 9.7 3.7 5.5 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Vps52 PF04129.12 EGC32135.1 - 1.5e-67 228.5 38.5 5e-63 213.6 27.1 2.6 2 1 1 3 3 3 2 Vps52 / Sac2 family RAI1 PF08652.11 EGC32135.1 - 0.12 12.6 0.9 2.2 8.5 0.2 3.2 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease BSD PF03909.17 EGC32135.1 - 0.75 9.8 4.4 4.3 7.4 0.1 3.4 3 0 0 3 3 3 0 BSD domain Adeno_E3A PF05248.12 EGC32136.1 - 0.11 12.5 0.0 0.16 12.0 0.0 1.2 1 0 0 1 1 1 0 Adenovirus E3A UQ_con PF00179.26 EGC32137.1 - 2.1e-16 59.8 0.0 2.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF5071 PF16804.5 EGC32137.1 - 0.15 12.4 0.0 4.2 7.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF5071) Sec6 PF06046.13 EGC32138.1 - 3e-133 445.2 13.7 3e-133 445.2 13.7 2.0 2 0 0 2 2 2 1 Exocyst complex component Sec6 Sec20 PF03908.13 EGC32138.1 - 0.0014 18.5 7.0 0.0041 17.0 0.4 4.0 1 1 3 4 4 4 1 Sec20 CHDCT2 PF08074.11 EGC32138.1 - 2.9 8.0 6.6 0.44 10.7 1.3 2.4 2 1 1 3 3 3 0 CHDCT2 (NUC038) domain RhoGAP PF00620.27 EGC32139.1 - 2.8e-21 75.9 0.1 8.4e-21 74.4 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Mem_trans PF03547.18 EGC32139.1 - 0.0071 14.8 1.6 0.012 14.1 1.6 1.3 1 0 0 1 1 1 1 Membrane transport protein DUF3328 PF11807.8 EGC32139.1 - 0.04 13.7 0.0 0.06 13.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) DUF4500 PF14937.6 EGC32139.1 - 0.051 13.6 0.9 0.19 11.8 0.9 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Acatn PF13000.7 EGC32139.1 - 0.067 11.7 5.5 0.021 13.3 2.6 1.6 2 0 0 2 2 2 0 Acetyl-coenzyme A transporter 1 SID-1_RNA_chan PF13965.6 EGC32139.1 - 0.12 10.8 4.5 0.22 9.9 4.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 EGC32139.1 - 0.21 10.3 16.3 0.37 9.5 16.3 1.4 1 0 0 1 1 1 0 Presenilin TMEM144 PF07857.12 EGC32139.1 - 0.35 9.8 1.1 0.65 8.9 1.1 1.4 1 0 0 1 1 1 0 Transmembrane family, TMEM144 of transporters Neur_chan_memb PF02932.16 EGC32139.1 - 0.39 10.7 5.1 0.3 11.1 3.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region EMC3_TMCO1 PF01956.16 EGC32139.1 - 0.54 10.0 4.8 1.2 8.8 4.8 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Zip PF02535.22 EGC32139.1 - 1.8 7.7 9.0 3.6 6.7 9.0 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.13 EGC32139.1 - 2.9 6.6 8.6 3.4 6.4 8.5 1.4 1 1 0 1 1 1 0 Otopetrin DUF4407 PF14362.6 EGC32139.1 - 3.2 7.0 15.3 5.4 6.3 15.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Serinc PF03348.15 EGC32139.1 - 7.3 5.4 11.7 19 4.0 11.7 1.8 1 1 0 1 1 1 0 Serine incorporator (Serinc) Peptidase_C48 PF02902.19 EGC32140.1 - 3.2e-23 82.7 0.9 3.2e-23 82.7 0.9 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L23eN PF03939.13 EGC32141.1 - 3.3e-16 59.2 9.4 8.8e-16 57.9 9.4 1.8 1 0 0 1 1 1 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.20 EGC32141.1 - 1.7e-13 50.7 1.5 1.7e-13 50.7 1.5 2.7 2 2 0 2 2 2 1 Ribosomal protein L23 SEP PF08059.13 EGC32142.1 - 9.2e-26 90.2 0.0 2.3e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 SEP domain UBA_4 PF14555.6 EGC32142.1 - 3.3e-16 58.8 0.5 1.1e-15 57.2 0.5 1.9 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.20 EGC32142.1 - 1.5e-14 53.9 0.0 4e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain TAP_C PF03943.13 EGC32142.1 - 0.026 14.2 0.2 0.066 12.9 0.2 1.7 1 1 0 1 1 1 0 TAP C-terminal domain FtsH_ext PF06480.15 EGC32142.1 - 1.6 9.1 13.8 0.37 11.2 4.4 2.6 2 0 0 2 2 2 0 FtsH Extracellular DUF4611 PF15387.6 EGC32142.1 - 6.5 7.0 18.6 10 6.4 4.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) Coiled PF05710.12 EGC32143.1 - 1.1e-22 80.6 17.3 1.5e-22 80.2 17.3 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC32144.1 - 0.22 12.4 4.6 0.33 11.8 4.6 1.5 1 1 0 1 1 1 0 Coiled coil adh_short PF00106.25 EGC32145.1 - 1.7e-32 112.5 0.0 2.5e-32 111.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC32145.1 - 3.3e-23 82.5 0.0 4.5e-23 82.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC32145.1 - 7.6e-05 22.7 0.0 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGC32145.1 - 0.18 11.7 0.0 0.27 11.1 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_10 PF13460.6 EGC32145.1 - 0.19 11.6 0.1 0.36 10.7 0.1 1.4 1 0 0 1 1 1 0 NAD(P)H-binding Ras PF00071.22 EGC32148.1 - 1.6e-28 99.4 0.4 2.3e-28 98.8 0.4 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32148.1 - 1.8e-13 50.8 0.0 3.4e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32148.1 - 0.00087 18.8 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC32148.1 - 0.0098 16.0 0.0 0.019 15.0 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Auxin_BP PF02041.16 EGC32148.1 - 0.098 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Ras PF00071.22 EGC32149.1 - 2.7e-36 124.6 1.2 3.5e-36 124.2 1.2 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32149.1 - 6.6e-16 58.6 0.1 1.4e-15 57.6 0.1 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32149.1 - 0.0003 20.3 1.0 0.00049 19.6 1.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family DUF5383 PF17355.2 EGC32150.1 - 0.66 10.4 3.0 2 8.8 2.8 2.0 1 1 1 2 2 2 0 Family of unknown function (DUF5383) Bromodomain PF00439.25 EGC32151.1 - 8.2e-20 70.7 2.5 4.2e-19 68.4 2.5 2.4 1 0 0 1 1 1 1 Bromodomain LapA_dom PF06305.11 EGC32152.1 - 2.5 8.0 7.5 4.7 7.1 0.0 3.4 3 0 0 3 3 3 0 Lipopolysaccharide assembly protein A domain DUF3730 PF12530.8 EGC32154.1 - 4.9e-58 196.4 2.9 4.9e-58 196.4 2.9 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3730) DASH_Dad2 PF08654.10 EGC32154.1 - 0.22 12.0 7.2 0.11 12.9 1.0 3.8 2 0 0 2 2 2 0 DASH complex subunit Dad2 PuR_N PF09182.10 EGC32154.1 - 0.27 11.2 1.6 8.4 6.4 0.1 3.4 3 0 0 3 3 3 0 Bacterial purine repressor, N-terminal DUF3236 PF11576.8 EGC32154.1 - 0.97 9.1 5.6 2.1 8.1 0.0 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3236) Myotub-related PF06602.14 EGC32155.1 - 4e-130 433.8 9.3 9e-71 238.6 3.9 2.8 2 1 1 3 3 3 2 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 EGC32155.1 - 1.5e-13 50.9 8.6 1.8e-06 28.2 0.1 4.8 5 0 0 5 5 5 3 N-terminal or F0 domain of Talin-head FERM GRAM PF02893.20 EGC32155.1 - 0.00091 19.1 0.2 0.0028 17.5 0.2 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase PF00102.27 EGC32155.1 - 0.0016 18.1 1.9 0.0016 18.1 1.9 2.3 2 1 0 2 2 2 1 Protein-tyrosine phosphatase FERM_N PF09379.10 EGC32155.1 - 0.0078 16.1 0.0 0.063 13.2 0.0 2.5 2 0 0 2 2 2 1 FERM N-terminal domain RBD PF02196.15 EGC32155.1 - 0.0093 16.0 0.1 0.048 13.7 0.0 2.2 2 0 0 2 2 2 1 Raf-like Ras-binding domain DSPc PF00782.20 EGC32155.1 - 0.067 13.0 0.0 0.067 13.0 0.0 3.3 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain PI3K_rbd PF00794.18 EGC32155.1 - 0.077 13.2 8.8 0.27 11.4 0.1 3.7 4 0 0 4 4 4 0 PI3-kinase family, ras-binding domain Y_phosphatase3 PF13350.6 EGC32155.1 - 0.18 11.7 0.0 0.36 10.8 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family DEAD PF00270.29 EGC32156.1 - 5.4e-36 124.0 0.0 1.2e-35 122.9 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC32156.1 - 3.2e-31 108.0 2.3 8.7e-28 96.9 1.1 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain DEAD PF00270.29 EGC32157.1 - 1.9e-52 177.6 0.1 6.3e-52 175.9 0.1 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC32157.1 - 5e-23 81.6 1.8 2.3e-22 79.4 0.0 3.1 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DBP10CT PF08147.12 EGC32157.1 - 2.5e-11 43.6 8.1 2.5e-11 43.6 8.1 4.4 4 2 0 4 4 4 1 DBP10CT (NUC160) domain AAA_22 PF13401.6 EGC32157.1 - 0.05 13.9 0.0 0.17 12.2 0.0 1.9 1 0 0 1 1 1 0 AAA domain p450 PF00067.22 EGC32158.1 - 1.6e-18 66.7 0.0 1.7e-18 66.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-TRAF PF02176.18 EGC32159.1 - 3.6e-13 50.0 21.8 5.4e-09 36.6 5.8 4.3 3 1 2 5 5 5 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC32159.1 - 0.00024 20.9 6.7 0.00024 20.9 6.7 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.26 EGC32159.1 - 0.046 13.9 1.4 0.13 12.4 0.3 2.4 2 0 0 2 2 2 0 MATH domain zf-U11-48K PF05253.12 EGC32159.1 - 0.097 12.6 5.6 21 5.1 0.4 4.1 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger Spc42p PF11544.8 EGC32160.1 - 0.015 15.2 0.9 0.017 15.1 0.9 1.0 1 0 0 1 1 1 0 Spindle pole body component Spc42p SlyX PF04102.12 EGC32160.1 - 0.023 15.3 0.8 0.024 15.3 0.8 1.0 1 0 0 1 1 1 0 SlyX Phage_Mu_Gam PF07352.12 EGC32160.1 - 0.023 14.6 1.0 0.023 14.6 1.0 1.1 1 0 0 1 1 1 0 Bacteriophage Mu Gam like protein OTU PF02338.19 EGC32161.1 - 1.9e-11 44.6 0.1 2.4e-11 44.2 0.1 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4962 PF16332.5 EGC32161.1 - 0.087 11.3 0.3 0.12 10.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4962) Chromo PF00385.24 EGC32162.1 - 8.6e-06 25.6 0.6 1.2e-05 25.1 0.6 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TolA_bind_tri PF16331.5 EGC32163.1 - 0.00065 19.7 0.7 0.00065 19.7 0.7 3.5 3 1 1 4 4 4 1 TolA binding protein trimerisation LPP PF04728.13 EGC32163.1 - 0.098 13.1 11.6 0.81 10.1 1.3 4.2 3 0 0 3 3 3 0 Lipoprotein leucine-zipper OmpH PF03938.14 EGC32163.1 - 3.4 8.0 59.4 0.46 10.8 0.2 4.5 3 1 1 4 4 4 0 Outer membrane protein (OmpH-like) SbcD_C PF12320.8 EGC32163.1 - 3.5 8.0 14.5 0.24 11.7 0.4 4.7 3 2 1 4 4 4 0 Type 5 capsule protein repressor C-terminal domain Phasin_2 PF09361.10 EGC32163.1 - 8.4 6.7 18.3 0.072 13.4 7.7 3.0 5 0 0 5 5 5 0 Phasin protein ketoacyl-synt PF00109.26 EGC32164.1 - 1.2e-63 215.1 0.0 1.8e-63 214.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32164.1 - 5.4e-42 144.4 0.0 8.8e-42 143.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC32164.1 - 2.7e-35 120.9 0.0 5.5e-35 119.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32164.1 - 1.1e-27 97.1 0.1 2.6e-27 95.9 0.1 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC32164.1 - 2.8e-19 69.5 0.0 4.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC32164.1 - 3e-17 63.1 0.1 9.2e-17 61.5 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EGC32164.1 - 2.7e-11 44.1 0.4 1.3e-09 38.6 0.0 3.7 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC32164.1 - 1e-08 36.3 0.0 2.7e-08 35.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC32164.1 - 8.9e-08 32.0 0.0 3.4e-07 30.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC32164.1 - 0.0014 18.9 0.0 0.0035 17.7 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC32164.1 - 0.1 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain adh_short PF00106.25 EGC32164.1 - 0.12 11.8 0.0 0.38 10.2 0.0 1.9 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_11 PF08241.12 EGC32164.1 - 0.15 12.7 0.0 0.48 11.1 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain IZUMO PF15005.6 EGC32164.1 - 2.1 8.8 5.7 20 5.7 1.1 3.6 2 0 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated PTPLA PF04387.14 EGC32165.1 - 6e-47 159.4 8.2 7.1e-47 159.2 8.2 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA UPF0020 PF01170.18 EGC32166.1 - 5.4e-16 58.9 0.0 9.7e-14 51.5 0.0 2.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 AviRa PF11599.8 EGC32166.1 - 0.0057 16.1 3.8 0.5 9.8 0.0 3.3 3 1 1 4 4 4 2 RRNA methyltransferase AviRa Methyltransf_31 PF13847.6 EGC32166.1 - 0.0063 16.3 6.3 0.098 12.4 6.3 2.6 2 1 0 2 2 2 1 Methyltransferase domain LIDHydrolase PF10230.9 EGC32166.1 - 0.055 13.0 3.2 0.12 11.9 3.2 1.5 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase Methyltransf_12 PF08242.12 EGC32166.1 - 0.12 13.2 5.4 0.14 12.9 0.2 2.8 2 0 0 2 2 2 0 Methyltransferase domain HflK_N PF12221.8 EGC32166.1 - 0.24 11.4 1.7 0.38 10.8 0.2 2.2 2 0 0 2 2 2 0 Bacterial membrane protein N terminal MitMem_reg PF13012.6 EGC32167.1 - 3.8e-28 98.2 1.9 1.2e-27 96.5 1.5 1.9 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGC32167.1 - 1.7e-24 86.1 0.0 2.9e-24 85.3 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease BSP_II PF05432.11 EGC32168.1 - 0.0058 16.4 40.8 0.0073 16.1 40.8 1.2 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Myc_N PF01056.18 EGC32168.1 - 0.009 16.0 13.0 0.011 15.6 13.0 1.3 1 0 0 1 1 1 1 Myc amino-terminal region DUF2052 PF09747.9 EGC32168.1 - 0.089 12.9 22.9 0.16 12.1 22.9 1.5 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 EGC32168.1 - 0.11 11.3 16.6 0.13 11.0 16.6 1.2 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3381 PF11861.8 EGC32168.1 - 0.17 11.7 30.7 0.03 14.1 26.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3381) CDC45 PF02724.14 EGC32168.1 - 0.17 10.1 20.5 0.2 9.9 20.5 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGC32168.1 - 0.18 11.1 28.1 0.25 10.6 28.1 1.1 1 0 0 1 1 1 0 BUD22 DUF913 PF06025.12 EGC32168.1 - 0.23 10.4 8.0 0.28 10.1 8.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) XRN_M PF17846.1 EGC32168.1 - 0.34 9.8 17.9 0.46 9.4 17.9 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DUF2457 PF10446.9 EGC32168.1 - 0.56 9.3 23.9 0.74 8.9 23.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF3306 PF11748.8 EGC32168.1 - 1.2 10.0 12.8 2.6 9.0 12.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3306) Nop14 PF04147.12 EGC32168.1 - 1.4 7.0 30.4 1.8 6.7 30.4 1.1 1 0 0 1 1 1 0 Nop14-like family RICTOR_N PF14664.6 EGC32168.1 - 4.6 6.1 12.0 0.35 9.8 2.7 2.1 1 1 1 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term Presenilin PF01080.17 EGC32168.1 - 6.9 5.3 19.7 8.7 5.0 19.7 1.1 1 0 0 1 1 1 0 Presenilin CobT PF06213.12 EGC32168.1 - 8 5.8 22.7 11 5.3 22.7 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Arf PF00025.21 EGC32169.1 - 4.3e-64 215.2 0.1 5.1e-64 214.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC32169.1 - 3.9e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC32169.1 - 1.8e-13 50.4 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC32169.1 - 5.6e-11 42.2 0.0 6.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC32169.1 - 2.1e-09 37.0 1.7 2e-06 27.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC32169.1 - 2.2e-07 30.5 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC32169.1 - 7.5e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGC32169.1 - 0.014 15.9 0.1 0.023 15.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter DUF4003 PF13170.6 EGC32169.1 - 0.057 12.8 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) SRP54 PF00448.22 EGC32169.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 EGC32169.1 - 0.16 10.9 0.0 4.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-CCHC PF00098.23 EGC32171.1 - 4.5e-05 23.3 2.0 0.00011 22.1 2.0 1.7 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGC32171.1 - 0.33 10.7 1.5 0.61 9.9 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle RRM_1 PF00076.22 EGC32172.1 - 3.2e-29 100.5 0.0 2.8e-14 52.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.20 EGC32172.1 - 2.2e-13 50.0 1.8 2.2e-13 49.9 0.1 2.0 2 0 0 2 2 2 1 Surp module CTD_bind PF04818.13 EGC32172.1 - 4e-13 50.0 0.1 1.1e-12 48.6 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 EGC32172.1 - 6.5e-10 38.7 0.0 0.00023 20.8 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC32172.1 - 6.1e-07 29.2 0.0 0.00012 21.9 0.0 2.3 2 0 0 2 2 2 1 Occluded RNA-recognition motif CTK3 PF12243.8 EGC32172.1 - 4.8e-05 23.4 0.2 9.3e-05 22.4 0.2 1.5 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 4HB_MCP_1 PF12729.7 EGC32172.1 - 0.012 15.1 1.3 0.021 14.4 1.3 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Adaptin_binding PF10199.9 EGC32172.1 - 0.025 15.2 0.1 0.068 13.8 0.1 1.8 1 0 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 RRM_3 PF08777.11 EGC32172.1 - 0.026 14.5 0.0 1.3 9.2 0.0 2.4 2 0 0 2 2 2 0 RNA binding motif Nup35_RRM_2 PF14605.6 EGC32172.1 - 0.16 12.0 0.0 4.3 7.4 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Xan_ur_permease PF00860.20 EGC32173.1 - 4.3e-70 236.4 42.2 1.9e-69 234.3 42.2 1.8 1 1 0 1 1 1 1 Permease family Tetraspanin PF00335.20 EGC32175.1 - 0.0058 16.4 2.5 0.05 13.3 3.3 1.9 1 1 1 2 2 2 1 Tetraspanin family DUF981 PF06168.11 EGC32175.1 - 0.011 15.7 2.9 0.013 15.5 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF981) Tmemb_170 PF10190.9 EGC32175.1 - 0.017 15.4 3.6 0.037 14.4 3.6 1.7 1 1 0 1 1 1 0 Putative transmembrane protein 170 DUF3810 PF12725.7 EGC32175.1 - 0.19 11.0 0.5 0.2 10.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) p450 PF00067.22 EGC32176.1 - 4.5e-44 151.0 0.0 5.1e-44 150.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.31 EGC32177.1 - 5.2e-12 45.8 0.0 4.3e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC32177.1 - 0.002 18.0 0.1 0.002 18.0 0.1 3.0 2 1 0 2 2 2 1 Myb DNA-binding like SR-25 PF10500.9 EGC32177.1 - 0.0054 16.4 6.3 0.0054 16.4 6.3 4.2 3 2 1 4 4 4 1 Nuclear RNA-splicing-associated protein DUF1192 PF06698.11 EGC32177.1 - 0.23 11.5 0.8 0.54 10.4 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) Pkinase PF00069.25 EGC32178.1 - 3.2e-73 246.3 1.1 7.2e-73 245.2 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32178.1 - 2.4e-33 115.5 0.0 5.1e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC32178.1 - 8.2e-10 38.5 0.0 2.4e-09 36.9 0.0 1.8 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC32178.1 - 2.3e-05 23.8 0.0 4.9e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGC32178.1 - 0.00049 19.8 0.3 0.00049 19.8 0.3 2.5 3 0 0 3 3 3 1 RIO1 family YrbL-PhoP_reg PF10707.9 EGC32178.1 - 0.0012 18.4 0.3 0.0012 18.4 0.3 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL HTH_Tnp_4 PF13613.6 EGC32180.1 - 0.0042 16.8 0.2 0.0087 15.8 0.2 1.6 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease SAM_1 PF00536.30 EGC32181.1 - 5.4e-09 36.4 0.9 0.0002 21.7 0.0 2.8 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC32181.1 - 5.4e-09 36.0 1.0 7.6e-05 22.7 0.1 2.7 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC32181.1 - 4e-05 23.5 1.3 0.011 15.7 0.1 2.7 3 0 0 3 3 3 2 Sterile alpha motif (SAM)/Pointed domain SAM_2 PF07647.17 EGC32182.1 - 0.00052 20.1 0.4 0.0043 17.1 0.1 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC32182.1 - 0.0098 16.3 0.1 0.018 15.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) NAD_binding_4 PF07993.12 EGC32183.1 - 2.9e-33 115.1 0.0 5e-33 114.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein ketoacyl-synt PF00109.26 EGC32184.1 - 4.1e-60 203.5 0.0 6.1e-60 202.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32184.1 - 2.1e-44 152.3 0.0 3.3e-44 151.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC32184.1 - 1.8e-28 98.9 0.0 3.7e-28 97.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32184.1 - 2.6e-24 86.1 0.0 4.4e-24 85.4 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC32184.1 - 4.2e-22 78.7 0.0 2.8e-21 76.1 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain PS-DH PF14765.6 EGC32184.1 - 2.7e-19 69.5 0.0 4.3e-19 68.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC32184.1 - 5.8e-12 46.1 0.1 1.9e-11 44.4 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC32184.1 - 1.6e-11 45.4 0.0 2.5e-10 41.5 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGC32184.1 - 5.7e-08 32.8 0.0 3.2e-07 30.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32184.1 - 2.9e-06 27.9 0.0 7.5e-06 26.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32184.1 - 4.2e-05 24.2 0.0 0.00017 22.3 0.0 2.2 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32184.1 - 0.00011 22.0 0.1 0.00089 19.1 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EGC32184.1 - 0.0002 20.8 0.0 0.00048 19.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGC32184.1 - 0.026 13.9 0.8 0.1 11.9 0.0 2.2 2 0 0 2 2 2 0 ubiE/COQ5 methyltransferase family NPM1-C PF16276.5 EGC32184.1 - 0.15 12.1 2.4 0.32 11.0 0.7 2.6 2 0 0 2 2 2 0 Nucleophosmin C-terminal domain HhH-GPD PF00730.25 EGC32185.1 - 1.5e-25 89.7 0.0 2.3e-25 89.2 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.23 EGC32185.1 - 2.3e-07 30.3 0.0 5.7e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.9 EGC32185.1 - 0.58 10.6 4.5 0.92 9.9 4.5 1.3 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III NAD_binding_4 PF07993.12 EGC32186.1 - 5e-47 160.2 0.0 8.9e-47 159.4 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGC32186.1 - 0.00092 18.7 0.0 0.0019 17.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC32186.1 - 0.063 12.7 1.5 0.26 10.6 0.0 2.1 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase KR PF08659.10 EGC32187.1 - 3.6e-23 82.4 0.0 7.2e-23 81.4 0.0 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 EGC32187.1 - 7.1e-08 33.6 0.0 1.5e-07 32.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GNAT_acetyltr_2 PF13718.6 EGC32187.1 - 0.067 12.6 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 GNAT acetyltransferase 2 Acyl_transf_1 PF00698.21 EGC32189.1 - 2.9e-43 148.6 0.0 4.2e-43 148.1 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.12 EGC32189.1 - 8.4e-23 81.0 0.0 6.4e-22 78.2 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.6 EGC32189.1 - 1.2e-19 70.7 0.0 1.9e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC32189.1 - 6.9e-12 45.8 0.0 1.8e-11 44.4 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGC32189.1 - 4.8e-08 33.0 0.0 1.7e-07 31.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32189.1 - 1.5e-06 28.8 0.0 3.3e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.22 EGC32189.1 - 1.6e-06 28.1 0.0 3.4e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_31 PF13847.6 EGC32189.1 - 7.4e-06 25.8 0.1 2.9e-05 23.9 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32189.1 - 7.8e-06 26.5 0.0 2.1e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain HTH_23 PF13384.6 EGC32189.1 - 0.00095 18.9 0.1 0.002 17.9 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.6 EGC32189.1 - 0.0019 18.1 0.0 0.004 17.1 0.0 1.5 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EGC32189.1 - 0.0065 16.6 0.1 0.012 15.7 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain Ubie_methyltran PF01209.18 EGC32189.1 - 0.011 15.1 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family HTH_38 PF13936.6 EGC32189.1 - 0.029 14.1 0.2 0.081 12.7 0.2 1.8 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EGC32189.1 - 0.11 12.5 0.6 0.43 10.6 0.2 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain ketoacyl-synt PF00109.26 EGC32190.1 - 4.4e-36 124.8 5.7 2.2e-21 76.6 5.7 4.1 1 1 1 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC32190.1 - 1.5e-19 70.2 0.0 3.2e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGC32190.1 - 2.3e-05 23.9 0.2 3.4e-05 23.3 0.2 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Pkinase PF00069.25 EGC32191.1 - 4.5e-57 193.4 0.1 1.2e-56 192.0 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32191.1 - 1.5e-30 106.3 0.0 2.9e-30 105.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HhH-GPD PF00730.25 EGC32191.1 - 1.1e-24 86.9 0.0 2.3e-24 85.9 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SAM_1 PF00536.30 EGC32191.1 - 8.6e-11 42.1 1.0 1e-09 38.7 0.1 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC32191.1 - 2.1e-09 37.3 0.0 7.6e-09 35.6 0.0 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HHH PF00633.23 EGC32191.1 - 1.1e-06 28.2 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif APH PF01636.23 EGC32191.1 - 3.6e-05 23.8 0.0 0.00081 19.4 0.3 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC32191.1 - 0.0013 18.3 0.0 0.0034 17.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGC32191.1 - 0.074 12.4 0.7 0.38 10.1 0.0 2.2 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EndIII_4Fe-2S PF10576.9 EGC32191.1 - 1.8 9.0 4.5 3.4 8.1 4.5 1.5 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Pkinase PF00069.25 EGC32192.1 - 7.3e-57 192.7 0.0 1.5e-56 191.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32192.1 - 3.5e-31 108.4 0.0 5.7e-31 107.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.30 EGC32192.1 - 6e-11 42.6 0.0 1.6e-10 41.2 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC32192.1 - 1.5e-08 34.7 0.4 4.9e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) APH PF01636.23 EGC32192.1 - 0.0069 16.3 0.0 0.063 13.2 0.3 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC32192.1 - 0.013 15.1 0.2 0.028 14.0 0.2 1.7 1 0 0 1 1 1 0 RIO1 family Kinase-like PF14531.6 EGC32192.1 - 0.025 13.9 0.0 0.095 12.0 0.0 1.9 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.25 EGC32193.1 - 1.9e-58 197.9 0.0 2.3e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32193.1 - 6.3e-30 104.3 0.0 7.9e-30 104.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC32193.1 - 5.4e-05 23.2 0.1 0.00031 20.7 0.3 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC32193.1 - 8.4e-05 22.2 0.2 0.00012 21.8 0.2 1.3 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGC32193.1 - 0.01 15.1 0.1 0.03 13.7 0.1 1.9 1 1 1 2 2 2 0 Kinase-like Kdo PF06293.14 EGC32193.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.6 EGC32195.1 - 1.6e-10 41.2 11.0 2.4e-10 40.5 11.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC32195.1 - 1.3e-08 34.6 7.6 1.9e-08 34.0 7.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC32195.1 - 1.7e-08 34.2 11.8 2.9e-08 33.4 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC32195.1 - 2.3e-07 31.0 10.1 4.7e-07 30.0 10.1 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC32195.1 - 3e-07 30.2 12.2 5.3e-07 29.4 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC32195.1 - 2.3e-05 24.1 6.2 4.2e-05 23.3 6.2 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC32195.1 - 0.00084 19.3 9.9 0.0014 18.5 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain TACC_C PF05010.14 EGC32195.1 - 0.0033 17.3 16.0 0.0033 17.3 16.0 2.4 1 1 0 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_UBOX PF13445.6 EGC32195.1 - 0.0041 17.1 6.7 0.009 16.0 6.7 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC32195.1 - 0.0069 16.2 10.3 0.014 15.1 10.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC32195.1 - 0.014 15.5 5.3 0.04 14.0 5.3 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC32195.1 - 0.023 14.8 10.6 0.058 13.6 9.4 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC32195.1 - 0.024 14.7 4.7 0.048 13.7 4.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RVT PF13966.6 EGC32195.1 - 0.032 14.9 4.4 0.037 14.7 0.8 2.6 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase IBR PF01485.21 EGC32195.1 - 0.048 13.9 12.0 0.077 13.2 10.7 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_11 PF17123.5 EGC32195.1 - 0.14 11.9 5.7 0.29 10.9 5.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGC32195.1 - 0.15 12.2 7.2 0.29 11.3 7.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC32195.1 - 0.29 10.8 8.7 0.48 10.1 8.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Monooxygenase_B PF04744.12 EGC32195.1 - 0.44 9.3 2.7 0.16 10.7 0.2 1.5 2 0 0 2 2 2 0 Monooxygenase subunit B protein DUF5001 PF16392.5 EGC32195.1 - 3.2 7.7 8.5 3.3 7.7 0.4 2.7 2 0 0 2 2 2 0 Ig-like domain DUF4094 PF13334.6 EGC32196.1 - 0.061 13.8 0.2 0.15 12.5 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) TACC_C PF05010.14 EGC32197.1 - 0.0005 19.9 23.6 0.0032 17.3 12.3 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Neur_chan_memb PF02932.16 EGC32197.1 - 3.6 7.6 9.9 6.3 6.8 9.9 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Glyco_transf_41 PF13844.6 EGC32197.1 - 7.4 4.9 8.3 5.8 5.2 6.7 1.5 1 1 0 1 1 1 0 Glycosyl transferase family 41 Erf4 PF10256.9 EGC32198.1 - 0.00031 20.8 1.8 0.00031 20.8 1.8 2.7 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family RST PF12174.8 EGC32198.1 - 0.36 10.8 2.1 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 RCD1-SRO-TAF4 (RST) plant domain FUSC_2 PF13515.6 EGC32198.1 - 2.7 8.1 7.9 4.4 7.4 7.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Amidohydro_1 PF01979.20 EGC32199.1 - 1e-29 103.9 0.1 2e-29 103.0 0.1 1.5 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGC32199.1 - 9.8e-12 45.1 0.6 1.8e-05 24.4 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.14 EGC32199.1 - 1.6e-05 24.9 0.3 2.5e-05 24.2 0.3 1.4 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.24 EGC32199.1 - 0.061 12.7 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel TACC_C PF05010.14 EGC32200.1 - 0.0027 17.5 4.8 0.0027 17.5 4.8 2.8 2 1 1 3 3 3 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PspB PF06667.12 EGC32200.1 - 0.28 11.3 3.5 12 6.0 0.1 2.9 2 0 0 2 2 2 0 Phage shock protein B OTU PF02338.19 EGC32201.1 - 1.3e-11 45.1 0.0 1.3e-11 45.1 0.0 3.2 2 1 0 2 2 2 1 OTU-like cysteine protease Presenilin PF01080.17 EGC32201.1 - 0.054 12.3 8.6 0.068 11.9 8.6 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC32201.1 - 0.24 11.4 43.4 0.35 10.8 43.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 EGC32201.1 - 7.7 6.2 17.2 12 5.6 17.2 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain LMBR1 PF04791.16 EGC32201.1 - 9.3 5.0 13.1 14 4.4 13.1 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Peptidase_M20 PF01546.28 EGC32203.1 - 1.3e-32 113.2 0.0 1.5e-32 113.0 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC32203.1 - 5.7e-12 45.5 0.0 1.3e-11 44.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGC32203.1 - 7.9e-05 22.4 0.0 0.00016 21.4 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.14 EGC32203.1 - 0.046 12.7 0.0 0.071 12.1 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase Methyltransf_16 PF10294.9 EGC32204.1 - 3e-16 59.6 0.0 6e-16 58.7 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC32204.1 - 7.9e-07 29.1 0.0 1.4e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32204.1 - 8.9e-07 28.8 0.5 8.9e-07 28.8 0.5 2.1 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC32204.1 - 1.6e-06 28.8 0.1 1.6e-06 28.8 0.1 2.8 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32204.1 - 0.00051 20.7 0.0 0.0011 19.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGC32204.1 - 0.0011 18.4 1.3 0.0011 18.4 1.3 2.1 2 1 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 EGC32204.1 - 0.0027 18.3 0.0 0.0051 17.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGC32204.1 - 0.019 14.6 0.0 0.044 13.4 0.0 1.7 1 1 0 1 1 1 0 Nodulation protein S (NodS) SdrD_B PF17210.3 EGC32205.1 - 6.7e-11 42.4 0.2 2.4e-10 40.6 0.2 1.9 1 1 1 2 2 2 1 SdrD B-like domain CarboxypepD_reg PF13620.6 EGC32205.1 - 2.7e-06 27.5 2.0 3.9e-05 23.8 0.1 2.9 3 0 0 3 3 3 1 Carboxypeptidase regulatory-like domain CarbopepD_reg_2 PF13715.6 EGC32205.1 - 0.01 15.8 0.9 0.064 13.3 0.2 2.6 2 1 0 2 2 2 0 CarboxypepD_reg-like domain Porin_5 PF16930.5 EGC32205.1 - 0.086 11.3 0.0 0.13 10.7 0.0 1.1 1 0 0 1 1 1 0 Putative porin Cag12 PF13117.6 EGC32205.1 - 0.1 13.1 0.2 0.23 12.0 0.2 1.5 1 0 0 1 1 1 0 Cag pathogenicity island protein Cag12 SapB_2 PF03489.17 EGC32206.1 - 9.6e-08 32.0 2.3 2.8e-07 30.5 1.1 2.3 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC32206.1 - 1.3e-07 31.5 1.2 1.3e-07 31.5 1.2 2.1 2 0 0 2 2 2 1 Saposin-like type B, region 1 Mvb12 PF09452.10 EGC32206.1 - 0.051 14.0 0.4 4.6 7.7 0.0 2.5 1 1 1 2 2 2 0 ESCRT-I subunit Mvb12 Beach PF02138.18 EGC32207.1 - 3.9e-127 423.3 0.2 3.9e-127 423.3 0.2 3.2 3 0 0 3 3 3 1 Beige/BEACH domain WD40 PF00400.32 EGC32207.1 - 1.2e-12 48.1 13.0 2.2e-05 25.1 0.2 5.1 4 0 0 4 4 4 4 WD domain, G-beta repeat PH_BEACH PF14844.6 EGC32207.1 - 6.5e-11 42.2 3.3 8.4e-11 41.9 0.0 3.1 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Kinetochor_Ybp2 PF08568.10 EGC32208.1 - 5.8e-16 58.1 2.1 6.5e-11 41.4 0.9 2.7 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin Presenilin PF01080.17 EGC32208.1 - 1.8 7.3 5.2 16 4.1 2.8 2.3 2 0 0 2 2 2 0 Presenilin FAM53 PF15242.6 EGC32209.1 - 7 6.4 11.9 9.7 5.9 11.9 1.2 1 0 0 1 1 1 0 Family of FAM53 Dimer_Tnp_hAT PF05699.14 EGC32211.1 - 8.6e-14 51.1 0.2 1e-13 50.9 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TFIIA PF03153.13 EGC32212.1 - 0.38 10.7 27.7 0.47 10.4 27.7 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDRGK PF09756.9 EGC32212.1 - 0.51 9.9 34.3 0.64 9.6 34.3 1.1 1 0 0 1 1 1 0 DDRGK domain Cwf_Cwc_15 PF04889.12 EGC32212.1 - 0.66 9.7 26.2 0.78 9.4 26.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Pinin_SDK_memA PF04696.13 EGC32212.1 - 2.6 8.1 29.1 3.7 7.6 29.1 1.2 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region PNISR PF15996.5 EGC32212.1 - 2.6 8.3 26.3 3.8 7.7 26.3 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR NPR3 PF03666.13 EGC32212.1 - 2.9 6.6 21.9 3.4 6.4 21.9 1.0 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 CNDH2_C PF16858.5 EGC32212.1 - 3.8 7.3 24.7 4.5 7.1 24.7 1.0 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Spt20 PF12090.8 EGC32212.1 - 4.3 6.9 25.6 5.4 6.6 25.6 1.2 1 0 0 1 1 1 0 Spt20 family Sec62 PF03839.16 EGC32212.1 - 7 6.1 14.3 7.7 6.0 14.3 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 RR_TM4-6 PF06459.12 EGC32212.1 - 9.6 5.9 18.5 11 5.7 18.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ank_4 PF13637.6 EGC32215.1 - 0.016 15.8 0.8 4.1 8.1 0.2 3.5 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC32217.1 - 0.087 13.4 2.6 5.3 7.8 0.2 3.6 4 0 0 4 4 4 0 Ankyrin repeats (many copies) I_LWEQ PF01608.17 EGC32220.1 - 3.8e-06 27.2 1.5 0.00028 21.2 0.2 3.2 2 2 2 4 4 4 1 I/LWEQ domain SipA_VBS PF17985.1 EGC32220.1 - 0.17 11.8 1.4 0.4 10.7 1.4 1.7 1 0 0 1 1 1 0 SipA vinculin binding site IPI_T4 PF11634.8 EGC32221.1 - 0.097 12.7 0.0 0.1 12.6 0.0 1.2 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 JAKMIP_CC3 PF16034.5 EGC32223.1 - 0.033 14.1 2.8 0.041 13.8 1.1 1.9 1 1 0 2 2 2 0 JAKMIP CC3 domain PRKG1_interact PF15898.5 EGC32223.1 - 0.039 14.9 5.5 0.055 14.4 1.7 2.1 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain DUF2868 PF11067.8 EGC32225.1 - 0.013 15.1 0.6 0.013 15.1 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2868) DUF639 PF04842.12 EGC32225.1 - 0.18 11.2 0.9 0.37 10.2 0.9 1.4 1 0 0 1 1 1 0 Plant protein of unknown function (DUF639) BAF1_ABF1 PF04684.13 EGC32225.1 - 0.4 9.7 28.2 0.52 9.3 28.2 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor HflK_N PF12221.8 EGC32225.1 - 4.2 7.5 9.6 3.4 7.8 3.3 2.5 2 0 0 2 2 2 0 Bacterial membrane protein N terminal FNIP PF05725.12 EGC32226.1 - 7.7e-09 35.6 8.5 7e-07 29.3 1.5 4.3 3 2 2 5 5 5 2 FNIP Repeat zf-B_box PF00643.24 EGC32226.1 - 6.3e-05 23.0 5.0 0.00012 22.2 5.0 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC32226.1 - 0.0069 16.5 2.5 0.015 15.5 2.5 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) CortBP2 PF09727.9 EGC32226.1 - 0.054 13.4 7.8 0.084 12.8 7.8 1.2 1 0 0 1 1 1 0 Cortactin-binding protein-2 Sec20 PF03908.13 EGC32226.1 - 0.95 9.4 11.8 0.47 10.4 4.1 2.5 1 1 1 2 2 2 0 Sec20 zf-TFIIIC PF12660.7 EGC32226.1 - 2 8.4 6.3 6.7 6.7 6.3 2.1 1 1 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex DUF2797 PF10977.8 EGC32226.1 - 2.8 7.8 5.8 0.27 11.1 0.8 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2797) zf-DBF PF07535.12 EGC32227.1 - 0.0014 18.6 1.0 0.0047 17.0 1.0 1.9 1 0 0 1 1 1 1 DBF zinc finger Myb_DNA-bind_4 PF13837.6 EGC32227.1 - 0.036 14.5 7.7 0.064 13.6 7.3 1.8 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain DUF5305 PF17231.2 EGC32227.1 - 0.69 9.3 10.4 2.7 7.3 0.6 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5305) zf-HC5HC2H PF13771.6 EGC32227.1 - 3.4 8.0 8.1 0.27 11.5 2.7 2.0 2 1 1 3 3 3 0 PHD-like zinc-binding domain OSTbeta PF15048.6 EGC32227.1 - 4.8 7.3 7.2 10 6.3 7.2 1.8 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein Menin PF05053.13 EGC32228.1 - 0.24 9.7 13.0 0.26 9.6 13.0 1.0 1 0 0 1 1 1 0 Menin NST1 PF13945.6 EGC32228.1 - 0.75 9.9 18.3 0.73 9.9 18.3 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator ALMT PF11744.8 EGC32228.1 - 4.5 6.0 6.9 4.7 5.9 6.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter Secretin_N_2 PF07655.13 EGC32228.1 - 5.3 7.7 19.9 7 7.3 19.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Presenilin PF01080.17 EGC32228.1 - 6.3 5.5 6.1 5.9 5.6 6.1 1.0 1 0 0 1 1 1 0 Presenilin NAD_binding_5 PF07994.12 EGC32229.1 - 1.7e-144 481.1 0.0 2e-144 480.9 0.0 1.0 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.17 EGC32229.1 - 8.7e-48 161.1 0.2 1.7e-47 160.1 0.2 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase TMF_TATA_bd PF12325.8 EGC32229.1 - 0.15 12.3 0.2 0.36 11.1 0.2 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding BRO1 PF03097.18 EGC32230.1 - 6e-26 91.2 0.1 7.6e-26 90.8 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain MFS_1 PF07690.16 EGC32231.1 - 2.4e-18 66.2 12.3 2.4e-18 66.2 12.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MNHE PF01899.16 EGC32231.1 - 4 7.2 8.2 2.7 7.8 0.4 2.7 2 1 0 2 2 2 0 Na+/H+ ion antiporter subunit RsgA_GTPase PF03193.16 EGC32233.1 - 6.2e-05 23.0 1.3 0.0013 18.7 0.1 2.9 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGC32233.1 - 0.00018 21.6 1.5 0.001 19.2 0.0 3.1 3 1 0 3 3 3 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGC32233.1 - 0.00073 20.1 9.0 0.00073 20.1 9.0 5.3 3 2 0 3 3 2 1 AAA domain GTP_EFTU PF00009.27 EGC32233.1 - 0.00086 18.9 0.1 0.0057 16.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain TsaE PF02367.17 EGC32233.1 - 0.0014 18.6 0.0 0.0041 17.1 0.0 1.8 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE MORN PF02493.20 EGC32233.1 - 0.0082 16.0 1.5 0.029 14.3 0.1 2.5 2 0 0 2 2 2 1 MORN repeat T2SSE PF00437.20 EGC32233.1 - 0.0092 15.1 0.0 0.018 14.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA PF00004.29 EGC32233.1 - 0.051 14.0 0.1 0.31 11.5 0.1 2.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC32233.1 - 0.061 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGC32233.1 - 0.084 12.6 0.0 0.28 11.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ResIII PF04851.15 EGC32233.1 - 0.14 12.2 0.1 0.14 12.2 0.1 3.3 4 0 0 4 4 4 0 Type III restriction enzyme, res subunit ABC_tran PF00005.27 EGC32233.1 - 0.34 11.4 0.1 0.34 11.4 0.1 2.8 3 1 0 3 3 3 0 ABC transporter Dynamin_N PF00350.23 EGC32233.1 - 0.34 10.9 6.6 0.65 10.0 0.0 3.8 3 1 1 4 4 4 0 Dynamin family MMR_HSR1 PF01926.23 EGC32234.1 - 3.8e-05 23.7 1.8 0.00016 21.7 0.1 3.0 3 1 1 4 4 4 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGC32234.1 - 0.00046 20.8 7.2 0.00046 20.8 7.2 4.9 3 2 0 3 3 2 1 AAA domain GTP_EFTU PF00009.27 EGC32234.1 - 0.0034 16.9 0.2 0.014 14.9 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC32234.1 - 0.0079 16.1 0.0 0.0079 16.1 0.0 3.3 3 1 1 4 4 4 1 RsgA GTPase MORN PF02493.20 EGC32234.1 - 0.022 14.6 2.2 0.029 14.3 0.1 2.4 2 0 0 2 2 2 0 MORN repeat ABC_tran PF00005.27 EGC32234.1 - 0.023 15.2 2.7 0.044 14.3 0.0 2.8 3 0 0 3 3 3 0 ABC transporter TsaE PF02367.17 EGC32234.1 - 0.024 14.7 0.0 0.07 13.1 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EGC32234.1 - 0.03 13.4 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.6 EGC32234.1 - 0.04 13.7 0.0 0.13 12.0 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGC32234.1 - 0.043 13.3 0.6 0.12 11.9 0.1 2.0 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EGC32234.1 - 0.098 13.1 0.0 0.49 10.8 0.0 2.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC32234.1 - 0.099 12.8 0.0 0.31 11.2 0.0 1.8 1 0 0 1 1 1 0 AAA domain PI3Ka PF00613.20 EGC32235.1 - 5.8e-61 205.1 1.1 1.1e-60 204.2 1.1 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGC32235.1 - 6.3e-57 193.3 0.0 3.6e-54 184.2 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGC32235.1 - 5.9e-40 136.4 0.2 1.1e-39 135.5 0.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF3430 PF11912.8 EGC32236.1 - 3.9e-13 49.9 35.1 4.9e-13 49.6 35.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC32236.1 - 0.0056 16.9 1.6 0.0056 16.9 1.6 2.9 2 2 1 3 3 3 1 Protein of unknown function (DUF3586) DUF4850 PF16142.5 EGC32236.1 - 0.029 13.9 0.2 0.046 13.2 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4850) GTP_EFTU PF00009.27 EGC32237.1 - 4e-55 186.4 0.1 5.4e-55 185.9 0.1 1.1 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGC32237.1 - 5.6e-23 81.4 0.3 1.5e-22 80.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGC32237.1 - 1.7e-15 57.1 1.6 3.8e-15 56.0 1.6 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC32237.1 - 2.8e-05 24.2 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase PTEN_C2 PF10409.9 EGC32238.1 - 2.6e-18 66.1 0.3 4.6e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.27 EGC32238.1 - 8.2e-11 41.9 0.0 1.5e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGC32238.1 - 2.1e-10 40.5 0.0 4.9e-10 39.3 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGC32238.1 - 0.0017 18.4 0.0 0.003 17.6 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGC32238.1 - 0.077 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGC32238.1 - 0.091 12.3 0.0 0.24 11.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family B_lectin PF01453.24 EGC32239.1 - 1.8e-06 28.4 0.0 0.0043 17.6 0.0 2.4 1 1 0 2 2 2 2 D-mannose binding lectin Pkinase PF00069.25 EGC32242.1 - 7.2e-53 179.6 2.1 1.9e-51 174.9 0.0 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32242.1 - 7.7e-50 169.6 0.0 2.5e-49 167.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC32242.1 - 0.00026 19.9 0.1 0.00026 19.9 0.1 2.5 3 0 0 3 3 3 1 Fungal protein kinase CD20 PF04103.15 EGC32242.1 - 0.026 14.6 0.1 0.026 14.6 0.1 2.8 3 0 0 3 3 3 0 CD20-like family Kdo PF06293.14 EGC32242.1 - 0.1 11.9 0.0 0.22 10.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Cadherin_C_2 PF16492.5 EGC32242.1 - 0.16 12.8 2.6 0.26 12.0 0.0 2.6 2 0 0 2 2 2 0 Cadherin cytoplasmic C-terminal OSTbeta PF15048.6 EGC32242.1 - 0.9 9.7 0.0 0.9 9.7 0.0 3.3 3 1 0 3 3 3 0 Organic solute transporter subunit beta protein BUD22 PF09073.10 EGC32243.1 - 2.1e-06 27.4 71.4 2.1e-06 27.4 71.4 3.6 1 1 1 2 2 2 1 BUD22 Nop PF01798.18 EGC32244.1 - 7.6e-70 235.0 0.9 1.6e-69 233.9 0.9 1.6 1 0 0 1 1 1 1 snoRNA binding domain, fibrillarin Prp31_C PF09785.9 EGC32244.1 - 7.9e-32 110.7 4.4 1.8e-31 109.6 4.4 1.6 1 0 0 1 1 1 1 Prp31 C terminal domain 2-Hacid_dh_C PF02826.19 EGC32244.1 - 0.21 10.9 1.6 0.56 9.6 0.1 2.2 2 0 0 2 2 2 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain RRN3 PF05327.11 EGC32245.1 - 7.2e-92 308.7 19.1 6.9e-51 173.4 2.8 3.8 3 1 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 Chromo_2 PF18704.1 EGC32245.1 - 0.074 13.3 0.9 0.4 11.0 0.0 2.6 2 0 0 2 2 2 0 Chromatin organization modifier domain 2 SDA1 PF05285.12 EGC32245.1 - 2 7.8 10.4 4.3 6.7 10.4 1.5 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGC32245.1 - 2.2 7.5 9.4 3.9 6.7 9.4 1.3 1 0 0 1 1 1 0 BUD22 GATA PF00320.27 EGC32246.1 - 1.9e-14 53.0 7.1 4e-14 51.9 7.1 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.7 EGC32246.1 - 0.1 12.6 3.6 0.36 10.9 3.6 1.9 1 0 0 1 1 1 0 Double zinc ribbon CCAP PF11105.8 EGC32246.1 - 1.5 8.8 5.2 0.36 10.8 1.9 1.7 2 0 0 2 2 2 0 Arthropod cardioacceleratory peptide 2a Menin PF05053.13 EGC32246.1 - 7.1 4.9 6.8 9.6 4.4 6.8 1.1 1 0 0 1 1 1 0 Menin SNARE_assoc PF09335.11 EGC32247.1 - 1.6e-12 47.9 5.0 1.6e-12 47.9 5.0 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein DPM3 PF08285.11 EGC32247.1 - 0.0013 18.9 0.5 0.0049 17.0 0.0 2.1 2 0 0 2 2 2 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FixP_N PF14715.6 EGC32247.1 - 0.011 15.4 0.2 0.011 15.4 0.2 2.5 2 0 0 2 2 2 0 N-terminal domain of cytochrome oxidase-cbb3, FixP RasGEF PF00617.19 EGC32248.1 - 9.1e-39 133.5 3.9 9.1e-39 133.5 3.9 2.1 2 0 0 2 2 2 1 RasGEF domain LRR_8 PF13855.6 EGC32248.1 - 2e-20 72.3 46.9 8.4e-07 28.7 4.4 6.2 3 2 4 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EGC32248.1 - 1.5e-18 66.6 58.2 0.00039 20.7 1.2 8.4 4 2 6 10 10 10 9 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 EGC32248.1 - 7e-08 32.7 4.6 1.1e-06 28.9 4.6 3.2 1 1 0 1 1 1 1 RasGEF N-terminal motif ABC2_membrane PF01061.24 EGC32249.1 - 1.4e-88 295.8 47.8 1.6e-49 168.1 21.6 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC32249.1 - 9.5e-49 165.4 0.1 4.6e-23 82.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC32249.1 - 2.8e-08 33.9 0.1 0.3 10.9 0.0 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGC32249.1 - 1.5e-07 31.4 0.7 0.0012 18.8 0.2 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGC32249.1 - 1.9e-07 31.7 0.0 0.014 15.8 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGC32249.1 - 4.7e-07 30.4 0.0 0.0094 16.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.19 EGC32249.1 - 1e-06 28.3 0.0 0.037 13.5 0.0 2.8 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGC32249.1 - 1.7e-06 28.4 0.2 0.1 12.9 0.0 2.8 2 1 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 EGC32249.1 - 6.8e-06 25.9 1.9 0.096 12.6 0.4 2.9 2 0 0 2 2 2 2 CDR ABC transporter AAA_33 PF13671.6 EGC32249.1 - 9.3e-06 25.9 0.0 0.091 12.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGC32249.1 - 1.1e-05 25.5 0.0 0.29 11.0 0.0 3.0 3 0 0 3 3 3 2 Rad17 P-loop domain AAA_29 PF13555.6 EGC32249.1 - 1.5e-05 24.7 0.4 0.0041 16.8 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGC32249.1 - 2.7e-05 24.5 0.1 0.31 11.4 0.0 3.3 3 0 0 3 3 3 2 RNA helicase AAA PF00004.29 EGC32249.1 - 3e-05 24.4 0.0 0.015 15.7 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.6 EGC32249.1 - 5.3e-05 23.5 0.2 0.22 11.7 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_23 PF13476.6 EGC32249.1 - 7.9e-05 23.2 2.6 1.3 9.5 0.0 3.3 2 1 0 3 3 3 2 AAA domain AAA_25 PF13481.6 EGC32249.1 - 0.00029 20.5 0.0 0.067 12.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGC32249.1 - 0.00053 20.1 0.1 1.5 8.9 0.2 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase IstB_IS21 PF01695.17 EGC32249.1 - 0.0016 18.2 0.0 2 8.1 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGC32249.1 - 0.0018 17.8 0.2 0.1 12.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing dynein motor region DUF2070 PF09843.9 EGC32249.1 - 0.0018 16.7 3.1 0.0018 16.7 3.1 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) Zeta_toxin PF06414.12 EGC32249.1 - 0.0018 17.6 0.0 0.44 9.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EGC32249.1 - 0.0021 17.8 0.0 2.8 7.6 0.0 2.3 2 0 0 2 2 2 2 AAA domain ATPase_2 PF01637.18 EGC32249.1 - 0.0026 17.7 0.0 2.8 7.8 0.0 2.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea DUF815 PF05673.13 EGC32249.1 - 0.0032 16.7 0.1 0.06 12.5 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 EGC32249.1 - 0.0033 17.4 0.3 2.2 8.2 0.0 2.6 2 0 0 2 2 2 1 NACHT domain AAA_17 PF13207.6 EGC32249.1 - 0.0034 17.8 0.0 3.7 8.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGC32249.1 - 0.0038 17.2 0.2 0.97 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Roc PF08477.13 EGC32249.1 - 0.0045 17.2 0.1 4.1 7.6 0.0 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase cobW PF02492.19 EGC32249.1 - 0.0059 16.2 0.4 3.3 7.3 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EGC32249.1 - 0.012 15.9 0.0 0.59 10.4 0.0 2.9 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit PDR_assoc PF08370.11 EGC32249.1 - 0.012 15.3 0.2 0.012 15.3 0.2 4.2 4 0 0 4 4 2 0 Plant PDR ABC transporter associated ABC2_membrane_3 PF12698.7 EGC32249.1 - 0.015 14.4 54.3 0.064 12.4 14.1 4.2 3 1 1 4 4 4 0 ABC-2 family transporter protein TsaE PF02367.17 EGC32249.1 - 0.017 15.1 0.2 4.1 7.4 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGC32249.1 - 0.029 14.7 0.1 0.84 10.0 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGC32249.1 - 0.031 14.0 0.3 10 5.8 0.1 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EGC32249.1 - 0.042 13.6 0.4 2.5 7.8 0.0 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGC32249.1 - 0.044 13.2 0.1 0.27 10.6 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit AAA_35 PF14516.6 EGC32249.1 - 0.073 11.9 0.0 3.7 6.3 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain DUF3139 PF11337.8 EGC32249.1 - 0.42 11.3 3.9 2.2 9.0 3.9 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) AAA_11 PF13086.6 EGC32249.1 - 0.53 10.0 0.0 0.53 10.0 0.0 2.3 3 0 0 3 3 3 0 AAA domain DUF4457 PF14652.6 EGC32250.1 - 8.9e-168 557.6 9.0 1.2e-122 409.2 1.8 4.6 4 1 1 5 5 5 3 Domain of unknown function (DUF4457) Sad1_UNC PF07738.13 EGC32250.1 - 3.5e-06 27.1 2.7 3.8 7.5 0.1 6.1 6 0 0 6 6 6 3 Sad1 / UNC-like C-terminal Flavokinase PF01687.17 EGC32251.1 - 1.1e-31 109.4 0.0 1.3e-31 109.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase DUF2778 PF10908.8 EGC32252.1 - 0.092 13.0 0.7 0.1 12.9 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2778) ABC2_membrane PF01061.24 EGC32253.1 - 3.8e-86 287.8 51.9 6.8e-46 156.3 16.9 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC32253.1 - 1.5e-50 171.3 1.2 1.2e-24 87.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGC32253.1 - 1.3e-08 34.9 0.7 0.0022 17.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGC32253.1 - 3.1e-08 33.8 2.2 0.24 11.2 0.0 4.5 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC32253.1 - 5.2e-08 33.5 0.0 0.0075 16.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.19 EGC32253.1 - 7e-08 32.2 1.1 0.00072 19.1 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGC32253.1 - 3e-07 31.1 0.1 0.017 15.7 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EGC32253.1 - 7.5e-07 29.5 0.1 0.032 14.5 0.1 2.7 2 1 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGC32253.1 - 6e-06 25.9 1.0 0.0042 16.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain PDR_assoc PF08370.11 EGC32253.1 - 6.9e-06 25.7 2.7 0.00031 20.4 0.3 3.0 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_25 PF13481.6 EGC32253.1 - 1.5e-05 24.6 0.0 0.039 13.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGC32253.1 - 2.8e-05 24.5 0.0 0.56 10.6 0.0 3.0 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 EGC32253.1 - 3e-05 24.1 0.0 0.044 13.7 0.0 2.5 2 0 0 2 2 2 2 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGC32253.1 - 5e-05 23.6 0.2 0.2 11.9 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_CDR PF06422.12 EGC32253.1 - 5.2e-05 23.1 2.5 0.1 12.5 0.3 2.7 2 0 0 2 2 2 2 CDR ABC transporter AAA PF00004.29 EGC32253.1 - 9.4e-05 22.8 0.1 0.18 12.2 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC32253.1 - 0.00013 22.1 0.1 0.43 10.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC32253.1 - 0.00019 21.5 0.2 0.7 10.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase NACHT PF05729.12 EGC32253.1 - 0.0002 21.3 0.4 0.11 12.5 0.0 2.4 2 0 0 2 2 2 1 NACHT domain Rad17 PF03215.15 EGC32253.1 - 0.00042 20.3 0.0 0.44 10.4 0.0 3.0 3 0 0 3 3 2 1 Rad17 P-loop domain Septin PF00735.18 EGC32253.1 - 0.00096 18.5 0.2 0.11 11.7 0.0 2.4 2 0 0 2 2 2 1 Septin cobW PF02492.19 EGC32253.1 - 0.002 17.7 1.2 1 8.9 0.1 2.4 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.14 EGC32253.1 - 0.0024 17.9 0.6 0.46 10.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) ABC2_membrane_3 PF12698.7 EGC32253.1 - 0.0025 17.0 43.4 0.0099 15.0 16.0 3.7 2 2 1 3 3 3 1 ABC-2 family transporter protein Zeta_toxin PF06414.12 EGC32253.1 - 0.0026 17.1 0.0 0.92 8.8 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_30 PF13604.6 EGC32253.1 - 0.0031 17.3 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGC32253.1 - 0.0061 16.1 0.2 0.38 10.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGC32253.1 - 0.0095 15.7 0.7 3.8 7.2 0.0 2.8 3 0 0 3 3 2 1 AAA domain Roc PF08477.13 EGC32253.1 - 0.0099 16.1 0.2 6.6 7.0 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase IstB_IS21 PF01695.17 EGC32253.1 - 0.012 15.4 0.0 7.2 6.3 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein ECF-ribofla_trS PF07155.12 EGC32253.1 - 0.022 14.8 0.6 0.022 14.8 0.6 3.0 3 0 0 3 3 2 0 ECF-type riboflavin transporter, S component AAA_17 PF13207.6 EGC32253.1 - 0.038 14.4 0.1 4.5 7.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF815 PF05673.13 EGC32253.1 - 0.047 12.8 1.4 0.49 9.5 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF815) FeoB_N PF02421.18 EGC32253.1 - 0.049 13.2 0.7 0.59 9.7 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.9 EGC32253.1 - 0.061 13.1 0.6 3.4 7.4 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RuvB_N PF05496.12 EGC32253.1 - 0.08 12.7 0.5 5 6.8 0.0 2.7 3 0 0 3 3 2 0 Holliday junction DNA helicase RuvB P-loop domain SbcCD_C PF13558.6 EGC32253.1 - 0.1 12.9 0.1 0.62 10.3 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.6 EGC32253.1 - 0.11 12.9 0.0 1.7 9.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_35 PF14516.6 EGC32253.1 - 0.11 11.3 0.0 13 4.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain TsaE PF02367.17 EGC32253.1 - 0.11 12.5 0.7 20 5.2 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EGC32253.1 - 0.18 11.4 0.9 21 4.7 0.1 2.8 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Ploopntkinase3 PF18751.1 EGC32253.1 - 0.22 11.4 0.2 5.9 6.8 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 Mg_chelatase PF01078.21 EGC32253.1 - 0.91 8.9 3.3 3.7 6.9 0.2 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.6 EGC32253.1 - 1.5 9.2 11.8 1.1 9.8 0.2 3.5 2 2 1 3 3 2 0 AAA domain WD40 PF00400.32 EGC32254.1 - 5.9e-45 150.4 30.4 5.2e-06 27.1 0.1 12.5 12 0 0 12 12 12 10 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32254.1 - 4.7e-07 30.0 8.1 0.81 10.0 0.0 7.0 6 1 2 8 8 8 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC32254.1 - 2e-05 23.7 17.9 0.014 14.3 0.0 4.8 4 2 2 6 6 6 3 WD40 region of Ge1, enhancer of mRNA-decapping protein CHCH PF06747.13 EGC32255.1 - 0.00068 19.7 4.5 0.0013 18.8 4.5 1.5 1 0 0 1 1 1 1 CHCH domain GCK PF07802.11 EGC32255.1 - 0.012 16.1 0.6 0.017 15.6 0.6 1.3 1 0 0 1 1 1 0 GCK domain zf-C6H2 PF15801.5 EGC32255.1 - 0.25 11.7 5.9 0.11 12.8 3.0 1.9 1 1 1 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding zinc-ribbons_6 PF07191.12 EGC32255.1 - 0.95 9.5 5.6 0.54 10.3 1.4 2.0 1 1 1 2 2 2 0 zinc-ribbons Cupin_8 PF13621.6 EGC32256.1 - 1.4e-27 97.0 0.7 1.9e-27 96.6 0.7 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGC32256.1 - 1.2e-05 25.7 0.3 4.9e-05 23.7 0.1 2.1 2 1 0 2 2 2 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGC32256.1 - 9.7e-05 22.0 0.0 0.00017 21.2 0.0 1.3 1 0 0 1 1 1 1 Cupin Adaptin_N PF01602.20 EGC32257.1 - 0.00027 19.6 1.0 0.00043 19.0 1.0 1.2 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.6 EGC32257.1 - 0.0003 21.1 0.2 0.012 16.0 0.1 2.8 1 1 1 2 2 2 1 HEAT repeats HEAT_EZ PF13513.6 EGC32257.1 - 0.0041 17.6 0.9 1.3 9.6 0.1 3.5 2 1 1 3 3 3 1 HEAT-like repeat HEAT PF02985.22 EGC32257.1 - 0.0046 17.1 0.3 0.092 13.1 0.0 3.1 3 0 0 3 3 3 1 HEAT repeat Arm PF00514.23 EGC32257.1 - 0.13 12.4 2.1 1.8 8.7 0.0 3.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat NMT PF01233.19 EGC32258.1 - 1.7e-77 258.7 0.0 3e-77 257.9 0.0 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.15 EGC32258.1 - 2.9e-64 216.5 2.8 2.9e-64 216.5 2.8 1.6 2 0 0 2 2 2 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.7 EGC32258.1 - 0.0018 18.4 0.0 0.1 12.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC32258.1 - 0.069 13.4 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family SpoVT_C PF15714.5 EGC32261.1 - 0.034 14.2 1.9 0.054 13.5 1.0 1.8 2 0 0 2 2 2 0 Stage V sporulation protein T C-terminal, transcription factor COMPASS-Shg1 PF05205.12 EGC32262.1 - 0.023 15.4 2.3 0.023 15.4 2.3 2.0 2 1 0 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 GPAT_N PF14829.6 EGC32262.1 - 0.12 12.3 0.2 0.26 11.3 0.2 1.5 1 0 0 1 1 1 0 Glycerol-3-phosphate acyltransferase N-terminal PEX11 PF05648.14 EGC32263.1 - 1.1e-58 198.4 3.6 1.2e-58 198.2 3.6 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) Mei4 PF13971.6 EGC32263.1 - 0.019 14.5 1.8 0.029 13.9 1.8 1.2 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 RasGEF PF00617.19 EGC32264.1 - 1.1e-53 182.1 0.1 1.1e-53 182.1 0.1 3.1 3 0 0 3 3 3 1 RasGEF domain LRR_8 PF13855.6 EGC32264.1 - 1.4e-35 120.8 74.5 1.5e-08 34.2 9.0 6.9 2 2 6 8 8 8 8 Leucine rich repeat LRR_4 PF12799.7 EGC32264.1 - 5.8e-25 87.0 56.1 4.7e-06 26.9 0.4 8.1 5 1 1 7 7 7 6 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 EGC32264.1 - 5.3e-22 78.1 2.8 3e-21 75.6 0.2 3.7 3 0 0 3 3 3 1 RasGEF N-terminal motif LRR_9 PF14580.6 EGC32264.1 - 4.9e-09 35.9 24.8 3.5e-05 23.4 2.3 4.4 3 1 0 4 4 4 3 Leucine-rich repeat LRR_5 PF13306.6 EGC32264.1 - 0.0015 18.5 21.0 0.0038 17.2 1.6 4.8 2 1 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) PAH PF02671.21 EGC32264.1 - 0.22 11.7 1.6 1.2 9.3 1.6 2.4 1 1 0 1 1 1 0 Paired amphipathic helix repeat IQ PF00612.27 EGC32264.1 - 1.1 9.2 9.6 0.87 9.5 3.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif Vpu PF00558.19 EGC32264.1 - 6.1 6.7 7.1 24 4.8 7.1 2.1 1 0 0 1 1 1 0 Vpu protein LRR_1 PF00560.33 EGC32264.1 - 7.6 7.5 38.4 72 4.5 0.1 11.4 11 0 0 11 11 11 0 Leucine Rich Repeat UCH PF00443.29 EGC32265.1 - 2.4e-33 115.7 19.6 2.7e-31 109.0 0.7 4.5 4 3 0 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC32265.1 - 3.3e-15 56.5 0.6 3.3e-15 56.5 0.6 4.8 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase UAE_UbL PF14732.6 EGC32265.1 - 3.5 8.3 12.0 0.086 13.4 1.1 3.9 5 0 0 5 5 5 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain CBS PF00571.28 EGC32266.1 - 7.9e-31 106.3 1.7 3.3e-15 56.3 0.2 2.1 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 EGC32266.1 - 9.3e-05 22.4 0.1 0.015 15.4 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF3659 PF12396.8 EGC32266.1 - 0.053 13.5 0.1 2.9 7.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) sCache_3_2 PF17203.4 EGC32266.1 - 0.083 13.0 0.1 0.45 10.6 0.1 2.0 1 1 1 2 2 2 0 Single cache domain 3 PcrB PF01884.17 EGC32266.1 - 0.12 11.8 0.2 0.34 10.3 0.2 1.7 1 1 0 1 1 1 0 PcrB family NMO PF03060.15 EGC32267.1 - 0.13 11.6 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 Nitronate monooxygenase Ras PF00071.22 EGC32269.1 - 8.2e-58 194.6 1.8 1e-57 194.2 1.8 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32269.1 - 3.6e-36 124.0 0.4 3.6e-36 124.0 0.4 1.6 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32269.1 - 1.3e-20 73.6 1.0 1.6e-20 73.3 1.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC32269.1 - 1.7e-07 30.9 0.5 2.1e-07 30.6 0.5 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGC32269.1 - 4.4e-06 26.3 2.9 2.7e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGC32269.1 - 7e-06 25.7 0.8 0.00015 21.3 0.6 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC32269.1 - 3.1e-05 24.0 0.3 5.6e-05 23.2 0.3 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGC32269.1 - 0.00043 19.5 0.6 0.06 12.5 0.0 2.9 1 1 2 3 3 3 1 G-protein alpha subunit TniB PF05621.11 EGC32269.1 - 0.00064 19.2 0.0 0.0013 18.2 0.0 1.6 1 0 0 1 1 1 1 Bacterial TniB protein RsgA_GTPase PF03193.16 EGC32269.1 - 0.0045 16.9 0.6 2.5 8.0 0.0 2.5 1 1 0 2 2 2 2 RsgA GTPase AAA_7 PF12775.7 EGC32269.1 - 0.0046 16.5 1.0 0.02 14.4 0.0 2.0 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_24 PF13479.6 EGC32269.1 - 0.0078 16.0 0.4 0.02 14.6 0.4 2.1 1 1 0 1 1 1 1 AAA domain OTCace_N PF02729.21 EGC32269.1 - 0.019 15.0 0.3 0.028 14.4 0.3 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain AAA_22 PF13401.6 EGC32269.1 - 0.022 15.0 0.5 2.5 8.4 0.0 2.6 1 1 2 3 3 3 0 AAA domain PduV-EutP PF10662.9 EGC32269.1 - 0.028 14.2 0.1 0.084 12.6 0.1 2.1 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGC32269.1 - 0.03 13.9 0.1 0.21 11.1 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA PF00004.29 EGC32269.1 - 0.044 14.2 0.2 0.18 12.3 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC32269.1 - 0.15 12.5 0.1 0.33 11.3 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain PEMT PF04191.13 EGC32270.1 - 3.5e-29 101.3 1.6 3.5e-29 101.3 1.6 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.14 EGC32270.1 - 0.0058 17.0 0.1 0.0058 17.0 0.1 1.9 2 1 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family NIDO PF06119.14 EGC32271.1 - 0.2 12.6 0.9 0.46 11.5 0.7 1.8 1 1 0 1 1 1 0 Nidogen-like Pho88 PF10032.9 EGC32272.1 - 1.3e-52 177.7 0.9 1.9e-52 177.2 0.9 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) RIC3 PF15361.6 EGC32272.1 - 3.7 7.9 0.0 3.7 7.9 0.0 3.0 2 1 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 Ank_2 PF12796.7 EGC32273.1 - 2.5e-23 82.5 7.4 1.3e-10 41.7 0.7 4.7 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC32273.1 - 7.2e-15 55.1 7.9 0.00082 19.9 0.0 5.6 5 2 0 5 5 5 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC32273.1 - 9.4e-14 51.3 1.2 0.0009 19.5 0.0 5.9 2 1 4 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC32273.1 - 1.2e-10 40.7 6.0 0.048 14.2 0.0 6.6 6 1 1 7 7 7 4 Ankyrin repeat Ank PF00023.30 EGC32273.1 - 0.0018 18.6 0.8 72 4.1 0.0 5.7 6 1 0 6 6 6 0 Ankyrin repeat DUF5049 PF16468.5 EGC32273.1 - 0.013 15.4 0.1 4 7.4 0.0 4.3 5 0 0 5 5 5 0 Domain of unknown function (DUF5049) TPR_1 PF00515.28 EGC32274.1 - 2.7e-08 33.3 0.4 0.0064 16.3 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32274.1 - 1.5e-07 31.0 1.9 0.0045 17.0 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32274.1 - 4.2e-06 26.5 5.0 0.0027 17.8 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32274.1 - 0.00038 20.7 0.6 0.0042 17.4 0.0 2.6 2 1 0 2 2 2 1 Tetratricopeptide repeat NARP1 PF12569.8 EGC32274.1 - 0.0033 16.4 2.8 0.031 13.2 0.6 2.1 1 1 1 2 2 2 1 NMDA receptor-regulated protein 1 ANAPC3 PF12895.7 EGC32274.1 - 0.0044 17.2 0.5 0.27 11.5 0.2 3.2 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_9 PF13371.6 EGC32274.1 - 0.0086 16.2 0.0 0.019 15.1 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32274.1 - 0.011 16.1 0.6 0.8 10.2 0.0 3.3 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32274.1 - 0.011 15.7 0.0 0.18 11.9 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32274.1 - 0.046 14.2 0.0 10 6.7 0.0 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32274.1 - 0.14 12.1 0.0 9 6.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32274.1 - 0.14 13.0 0.0 12 7.0 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat PBP3 PF18056.1 EGC32275.1 - 0.074 13.2 1.1 0.58 10.3 0.3 2.9 2 0 0 2 2 2 0 Penicillin Binding Protein 3 Domain Transposase_22 PF02994.14 EGC32275.1 - 0.23 11.6 4.5 1.1 9.5 4.5 2.2 1 0 0 1 1 1 0 L1 transposable element RBD-like domain LtrA PF06772.11 EGC32276.1 - 0.00025 20.4 0.1 0.00027 20.3 0.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF2207 PF09972.9 EGC32276.1 - 0.0023 16.8 0.1 0.0023 16.8 0.1 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4271 PF14093.6 EGC32276.1 - 0.0037 17.2 2.0 0.0046 16.9 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) Serinc PF03348.15 EGC32276.1 - 0.018 14.0 0.7 0.022 13.7 0.7 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Tetraspanin PF00335.20 EGC32276.1 - 0.024 14.3 3.2 0.039 13.6 3.2 1.4 1 0 0 1 1 1 0 Tetraspanin family Anoctamin PF04547.12 EGC32276.1 - 0.034 13.0 0.0 0.037 12.9 0.0 1.0 1 0 0 1 1 1 0 Calcium-activated chloride channel DUF5305 PF17231.2 EGC32276.1 - 0.12 11.8 0.2 0.12 11.8 0.2 1.6 1 1 1 2 2 2 0 Family of unknown function (DUF5305) NapE PF06796.11 EGC32276.1 - 0.14 11.7 1.3 0.67 9.5 0.1 2.1 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3185 PF11381.8 EGC32276.1 - 0.18 11.8 3.2 0.26 11.3 0.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3185) MARVEL PF01284.23 EGC32276.1 - 0.25 11.4 3.3 1 9.4 3.1 1.7 1 1 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.15 EGC32276.1 - 1.6 9.2 4.7 1.1 9.7 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF202) HECT PF00632.25 EGC32277.1 - 1.4e-81 274.4 1.8 1.4e-81 274.4 1.8 2.0 2 1 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Arm PF00514.23 EGC32277.1 - 0.0004 20.3 2.3 2.4 8.3 0.0 4.9 3 1 1 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT PF02985.22 EGC32277.1 - 0.057 13.7 0.4 31 5.2 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat SRTM1 PF15872.5 EGC32278.1 - 0.028 14.5 0.5 0.028 14.5 0.5 1.7 2 1 0 2 2 2 0 Serine-rich and transmembrane domain-containing protein 1 SH PF01445.17 EGC32278.1 - 0.036 14.0 0.4 0.061 13.3 0.4 1.3 1 0 0 1 1 1 0 Viral small hydrophobic protein EGF_2 PF07974.13 EGC32279.1 - 0.00057 20.2 17.9 0.0024 18.2 9.0 2.6 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.10 EGC32279.1 - 0.012 15.0 1.3 0.026 13.9 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Wzz PF02706.15 EGC32279.1 - 0.16 12.3 7.5 1.4 9.2 0.4 2.7 2 0 0 2 2 2 0 Chain length determinant protein EGF_alliinase PF04863.13 EGC32279.1 - 2.2 8.7 4.2 6.2 7.3 4.2 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain MOR2-PAG1_C PF14225.6 EGC32280.1 - 2.3e-11 44.0 0.1 7.7e-11 42.3 0.1 1.9 1 0 0 1 1 1 1 Cell morphogenesis C-terminal RGS PF00615.19 EGC32280.1 - 1.9e-08 34.6 0.1 1.9e-08 34.6 0.1 3.2 3 0 0 3 3 3 1 Regulator of G protein signaling domain TrkA_N PF02254.18 EGC32280.1 - 0.08 13.2 0.0 0.33 11.2 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain BAR PF03114.18 EGC32281.1 - 3.5e-15 56.3 21.0 4e-15 56.1 21.0 1.0 1 0 0 1 1 1 1 BAR domain BAR_3 PF16746.5 EGC32281.1 - 1.3e-12 48.0 12.7 1.3e-12 48.0 12.7 1.7 1 1 1 2 2 2 1 BAR domain of APPL family Arfaptin PF06456.13 EGC32281.1 - 4.3e-09 36.3 18.9 5.2e-09 36.0 18.9 1.0 1 0 0 1 1 1 1 Arfaptin-like domain Cep57_MT_bd PF06657.13 EGC32281.1 - 0.021 15.2 0.8 0.021 15.2 0.8 2.5 2 2 1 3 3 3 0 Centrosome microtubule-binding domain of Cep57 HALZ PF02183.18 EGC32281.1 - 0.029 14.6 2.5 0.43 10.8 0.2 2.9 2 1 0 2 2 2 0 Homeobox associated leucine zipper PerC PF06069.11 EGC32281.1 - 0.076 13.3 2.9 10 6.4 0.1 3.4 2 1 1 3 3 3 0 PerC transcriptional activator BAR_2 PF10455.9 EGC32281.1 - 0.3 10.2 20.6 0.63 9.1 20.6 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Ca_chan_IQ PF08763.11 EGC32281.1 - 0.38 11.0 2.7 1.4 9.2 0.7 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel IQ domain Big_9 PF17963.1 EGC32283.1 - 6e-19 68.6 85.9 2.2e-08 34.7 0.5 11.6 10 1 1 11 11 11 8 Bacterial Ig domain VWA PF00092.28 EGC32283.1 - 5e-07 30.1 1.0 2e-05 24.9 0.1 2.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Cadherin_5 PF17892.1 EGC32283.1 - 0.0045 16.9 24.8 0.16 11.9 0.0 7.8 8 1 0 8 8 8 2 Cadherin-like domain Cadherin_4 PF17803.1 EGC32283.1 - 0.41 11.3 75.0 0.36 11.5 0.1 11.7 12 1 1 13 13 13 0 Bacterial cadherin-like domain DUF5011 PF16403.5 EGC32283.1 - 0.88 9.7 9.6 8.8 6.5 0.7 4.3 3 0 0 3 3 3 0 Domain of unknown function (DUF5011) He_PIG PF05345.12 EGC32283.1 - 1.5 9.0 18.1 0.015 15.5 2.6 4.5 3 0 0 3 3 3 0 Putative Ig domain G8 PF10162.9 EGC32284.1 - 3e-25 88.7 1.0 6.2e-25 87.7 1.0 1.6 1 0 0 1 1 1 1 G8 domain PADR1 PF08063.12 EGC32284.1 - 0.092 12.6 4.6 0.22 11.3 0.3 3.0 2 0 0 2 2 2 0 PADR1 (NUC008) domain Glyoxalase PF00903.25 EGC32285.1 - 0.053 13.7 0.2 0.074 13.3 0.2 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TIG PF01833.24 EGC32286.1 - 2.5e-14 53.1 16.8 2.5e-08 33.9 1.9 4.1 3 0 0 3 3 3 2 IPT/TIG domain EGF_2 PF07974.13 EGC32286.1 - 1.3e-13 51.0 69.5 9.2e-06 25.9 7.8 5.0 4 0 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.24 EGC32286.1 - 0.0009 19.3 57.3 0.017 15.3 7.9 4.8 3 1 1 4 4 4 4 Laminin EGF domain hEGF PF12661.7 EGC32286.1 - 0.0049 17.4 4.3 0.0049 17.4 4.3 5.9 6 0 0 6 6 6 1 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGC32286.1 - 0.0088 16.1 9.7 0.0088 16.1 9.7 5.0 4 1 0 4 4 4 2 Tenascin EGF domain Nitrophorin PF02087.15 EGC32286.1 - 0.012 15.7 0.1 0.043 13.8 0.0 2.0 2 0 0 2 2 2 0 Nitrophorin CDP-OH_P_transf PF01066.21 EGC32287.1 - 5.2e-12 46.4 1.0 5.2e-12 46.4 1.0 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase FAM76 PF16046.5 EGC32288.1 - 0.00029 20.3 16.0 0.0004 19.8 16.0 1.1 1 0 0 1 1 1 1 FAM76 protein DUF4349 PF14257.6 EGC32288.1 - 0.037 13.5 0.0 0.067 12.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) SlyX PF04102.12 EGC32288.1 - 0.22 12.2 3.4 0.97 10.1 2.5 2.4 2 1 0 2 2 2 0 SlyX Med9 PF07544.13 EGC32288.1 - 0.52 10.4 9.3 0.42 10.7 7.5 1.9 2 1 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 LMBR1 PF04791.16 EGC32288.1 - 3.3 6.5 9.0 4 6.2 9.0 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein STAC2_u1 PF16664.5 EGC32288.1 - 3.5 8.1 7.9 9.4 6.7 7.5 2.0 1 1 0 1 1 1 0 Unstructured on SH3 and cysteine-rich domain-containing protein 2 PDDEXK_6 PF04720.12 EGC32288.1 - 3.5 7.5 9.4 5.8 6.8 9.4 1.4 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF3450 PF11932.8 EGC32288.1 - 4.6 6.5 10.1 2 7.7 7.9 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) DUF4482 PF14818.6 EGC32288.1 - 9.8 7.0 14.0 1.3 9.9 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4482) BTB PF00651.31 EGC32289.1 - 4.1e-07 30.2 0.4 3.9e-05 23.8 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain Secretin_N_2 PF07655.13 EGC32289.1 - 0.16 12.6 11.9 0.28 11.7 11.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Menin PF05053.13 EGC32289.1 - 1.3 7.3 5.8 1.7 6.9 5.8 1.1 1 0 0 1 1 1 0 Menin CelTOS PF18659.1 EGC32290.1 - 0.084 13.3 0.6 1.3 9.5 0.1 2.4 2 1 1 3 3 3 0 Cell-traversal protein for ookinetes and sporozoites DNTTIP1_dimer PF18192.1 EGC32290.1 - 0.094 13.1 2.6 0.17 12.2 0.1 2.5 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain Strep_SA_rep PF06696.11 EGC32290.1 - 0.49 10.4 2.6 3.7 7.7 0.7 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat WD40 PF00400.32 EGC32291.1 - 4.4e-05 24.1 1.2 0.49 11.4 0.0 4.1 4 0 0 4 4 4 1 WD domain, G-beta repeat Spt20 PF12090.8 EGC32291.1 - 0.029 14.0 26.4 0.046 13.3 26.4 1.2 1 0 0 1 1 1 0 Spt20 family Kisspeptin PF15152.6 EGC32291.1 - 0.044 14.6 0.5 1.9 9.3 0.1 2.7 3 0 0 3 3 3 0 Kisspeptin Presenilin PF01080.17 EGC32291.1 - 0.079 11.7 4.5 0.11 11.3 4.5 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC32291.1 - 0.42 10.6 18.8 0.57 10.1 18.8 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Folliculin PF11704.8 EGC32291.1 - 2.3 8.1 9.1 4.3 7.2 9.1 1.4 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3450 PF11932.8 EGC32291.1 - 5.5 6.2 15.8 8 5.7 15.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) PA28_beta PF02252.18 EGC32292.1 - 0.088 12.5 3.4 10 5.8 0.1 4.4 4 0 0 4 4 4 0 Proteasome activator pa28 beta subunit Ipi1_N PF12333.8 EGC32292.1 - 0.39 11.3 1.1 8.1 7.1 0.2 3.7 3 0 0 3 3 3 0 Rix1 complex component involved in 60S ribosome maturation PA26 PF04636.13 EGC32293.1 - 1.3e-157 525.3 0.1 1.6e-157 525.0 0.1 1.1 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Pro_isomerase PF00160.21 EGC32294.1 - 6.6e-44 150.0 0.5 7.2e-44 149.8 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.20 EGC32295.1 - 7.8e-12 45.3 1.5 7.8e-12 45.3 1.5 3.0 3 0 0 3 3 3 2 ENTH domain ANTH PF07651.16 EGC32295.1 - 0.00016 20.8 0.0 0.00016 20.8 0.0 3.1 3 1 1 4 4 4 1 ANTH domain YebO PF13974.6 EGC32295.1 - 0.59 10.2 11.6 0.068 13.2 4.7 2.8 2 0 0 2 2 2 0 YebO-like protein UPF0556 PF10572.9 EGC32296.1 - 1e-18 67.3 0.0 1.2e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Histone PF00125.24 EGC32297.1 - 9e-28 97.2 0.8 1e-27 97.1 0.8 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGC32297.1 - 1.9e-06 28.0 0.0 2.3e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC32297.1 - 0.0009 19.6 0.2 0.0013 19.1 0.2 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID-31kDa PF02291.15 EGC32297.1 - 0.0067 16.5 0.0 0.0089 16.1 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.23 EGC32297.1 - 0.011 16.0 0.0 0.017 15.4 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGC32297.1 - 0.056 13.5 0.2 0.15 12.1 0.1 1.6 1 1 1 2 2 2 0 Bromodomain associated Stomoxyn PF11585.8 EGC32297.1 - 0.18 11.8 0.3 3 7.9 0.1 2.2 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn Peptidase_M24 PF00557.24 EGC32300.1 - 7.9e-52 176.0 0.0 9.5e-52 175.7 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGC32300.1 - 9.7e-17 61.0 8.2 2.2e-16 59.9 8.2 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGC32300.1 - 0.00093 19.2 2.8 0.0019 18.2 2.8 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGC32300.1 - 0.023 14.6 3.8 0.06 13.2 3.8 1.8 1 0 0 1 1 1 0 HIT zinc finger FNIP PF05725.12 EGC32301.1 - 1.3e-41 140.5 66.3 2.8e-09 37.0 0.2 8.2 3 2 4 8 8 8 7 FNIP Repeat Diphthamide_syn PF01866.17 EGC32302.1 - 1.9e-71 241.0 3.8 5.2e-71 239.6 3.8 1.7 1 1 0 1 1 1 1 Putative diphthamide synthesis protein 5_nucleotid PF05761.14 EGC32303.1 - 1.7e-171 571.2 2.1 2e-171 571.0 2.1 1.0 1 0 0 1 1 1 1 5' nucleotidase family Trypsin_2 PF13365.6 EGC32304.1 - 2.1e-30 106.6 0.1 6.5e-18 66.1 0.0 2.5 2 0 0 2 2 2 2 Trypsin-like peptidase domain Peptidase_S46 PF10459.9 EGC32304.1 - 1.3e-06 27.4 8.2 0.018 13.7 0.0 4.1 4 0 0 4 4 4 3 Peptidase S46 Trypsin PF00089.26 EGC32304.1 - 1.3e-06 28.4 6.4 0.0053 16.6 4.1 4.2 2 1 0 2 2 2 2 Trypsin Nucleoporin_FG PF13634.6 EGC32305.1 - 4.1e-17 62.8 73.5 1e-09 39.1 36.4 5.6 2 2 2 4 4 4 2 Nucleoporin FG repeat region UPF0184 PF03670.13 EGC32305.1 - 0.048 14.1 0.2 0.048 14.1 0.2 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) RPW8 PF05659.11 EGC32305.1 - 0.084 12.6 1.2 0.19 11.4 0.2 2.0 1 1 1 2 2 2 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 BLOC1_2 PF10046.9 EGC32305.1 - 1.1 9.6 6.6 4.7 7.6 0.5 2.9 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DASH_Duo1 PF08651.10 EGC32305.1 - 6.1 6.7 6.4 4.7 7.1 0.3 3.3 3 0 0 3 3 3 0 DASH complex subunit Duo1 OTU PF02338.19 EGC32306.1 - 7.7e-13 49.0 0.3 3.3e-12 47.0 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease NAD_kinase PF01513.21 EGC32307.1 - 4e-62 210.0 0.0 1e-61 208.7 0.0 1.7 1 1 0 1 1 1 1 ATP-NAD kinase Sigma_reg_N PF13800.6 EGC32308.1 - 0.0027 18.0 0.7 0.0027 18.0 0.7 3.9 3 1 0 4 4 4 1 Sigma factor regulator N-terminal Tetraspanin PF00335.20 EGC32308.1 - 0.043 13.5 5.4 0.39 10.4 0.5 2.3 2 0 0 2 2 2 0 Tetraspanin family DUF2232 PF09991.9 EGC32308.1 - 0.3 10.2 6.6 2.4 7.3 0.6 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2232) VanZ PF04892.12 EGC32308.1 - 4.1 8.1 10.1 0.81 10.4 5.3 2.2 1 1 1 2 2 2 0 VanZ like family DUF4449 PF14613.6 EGC32309.1 - 0.00011 22.3 11.2 0.00011 22.3 11.2 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF4449) Rubis-subs-bind PF09273.11 EGC32310.1 - 3.1e-24 86.1 0.2 8e-24 84.8 0.2 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGC32310.1 - 5.9e-12 46.3 0.1 2.8e-11 44.1 0.0 1.9 2 0 0 2 2 2 1 SET domain PI3Ka PF00613.20 EGC32311.1 - 5.4e-59 198.7 0.7 1.2e-58 197.6 0.7 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGC32311.1 - 1.3e-50 172.5 0.4 1.9e-49 168.8 0.4 2.3 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGC32311.1 - 1.3e-15 57.5 0.0 3.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGC32311.1 - 1.2e-08 35.1 0.1 3.9e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGC32311.1 - 0.00052 19.5 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) HTH_40 PF14493.6 EGC32312.1 - 0.066 13.7 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain SNAP PF14938.6 EGC32313.1 - 2.7e-13 50.0 4.5 5.8e-13 48.9 4.5 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_1 PF00515.28 EGC32313.1 - 1.9e-06 27.5 4.2 0.00046 19.9 0.2 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32313.1 - 2.7e-06 27.0 3.9 0.001 19.0 0.2 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32313.1 - 5.5e-06 26.6 0.1 0.0011 19.3 0.1 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32313.1 - 0.00014 21.8 5.3 0.0011 19.0 0.2 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32313.1 - 0.00078 19.1 4.3 0.21 11.3 0.4 3.3 4 0 0 4 4 4 2 TPR repeat TPR_MalT PF17874.1 EGC32313.1 - 0.013 14.9 0.0 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 MalT-like TPR region TPR_19 PF14559.6 EGC32313.1 - 0.087 13.3 0.1 5.5 7.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC32313.1 - 0.25 11.6 2.5 6.5 7.1 0.0 3.0 4 0 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 LIM PF00412.22 EGC32314.1 - 2.2e-17 63.0 26.2 5.4e-11 42.6 9.4 3.2 3 0 0 3 3 3 2 LIM domain RSB_motif PF16294.5 EGC32315.1 - 1.8e-06 28.1 7.0 1.8e-06 28.1 7.0 4.6 2 2 1 3 3 3 1 RNSP1-SAP18 binding (RSB) motif Sec3_C PF09763.9 EGC32316.1 - 5.3e-168 560.6 34.9 7.1e-168 560.2 34.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 CCDC-167 PF15188.6 EGC32316.1 - 0.00069 19.9 0.4 0.0025 18.1 0.4 2.0 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 SR-25 PF10500.9 EGC32316.1 - 8 6.0 21.5 1.4 8.5 12.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein EF-hand_1 PF00036.32 EGC32317.1 - 1.5e-13 49.2 2.5 0.0011 18.3 0.1 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGC32317.1 - 3.1e-13 48.5 1.3 0.0017 18.1 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGC32317.1 - 2.4e-09 37.5 4.1 0.00011 22.6 0.3 2.9 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC32317.1 - 4.4e-07 29.1 0.5 0.32 10.6 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGC32317.1 - 1.6e-06 27.8 0.2 0.75 9.7 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC32317.1 - 0.0025 18.1 4.7 0.21 11.9 0.6 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Phage_TAC_12 PF12363.8 EGC32317.1 - 0.021 15.2 0.6 1.9 8.9 0.0 2.4 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC ZFYVE21_C PF16696.5 EGC32317.1 - 0.022 14.6 0.1 0.15 11.9 0.0 2.1 1 1 1 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus EF-hand_13 PF17958.1 EGC32317.1 - 0.053 13.3 0.1 12 5.8 0.0 2.5 2 1 0 2 2 2 0 EF-hand domain NDUF_B6 PF09782.9 EGC32318.1 - 1.5 8.9 6.0 26 4.9 0.1 3.1 2 1 1 3 3 3 0 NADH:ubiquinone oxidoreductase, NDUFB6/B17 subunit DUF3848 PF12959.7 EGC32318.1 - 7.6 6.7 9.7 36 4.5 0.2 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3848) DAO PF01266.24 EGC32319.1 - 3.4e-37 128.8 0.0 3.9e-37 128.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGC32319.1 - 0.0023 17.2 0.1 0.0062 15.8 0.0 1.7 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.6 EGC32319.1 - 0.096 12.9 0.0 0.21 11.9 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGC32319.1 - 0.16 11.2 0.0 0.72 9.0 0.0 1.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Bact_lectin PF18483.1 EGC32321.1 - 2e-25 90.0 2.6 4.5e-25 88.8 0.7 2.1 2 0 0 2 2 2 1 Bacterial lectin Lectin_legB PF00139.19 EGC32321.1 - 9.8e-21 74.4 0.1 1.7e-20 73.6 0.1 1.3 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.19 EGC32321.1 - 8.8e-14 51.9 0.1 9.6e-13 48.6 0.1 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily Lectin_leg-like PF03388.13 EGC32321.1 - 1.9e-07 30.7 1.0 4.9e-07 29.3 0.3 2.1 2 0 0 2 2 2 1 Legume-like lectin family PAW PF04721.17 EGC32321.1 - 0.00077 19.3 0.0 0.0019 18.0 0.0 1.7 1 0 0 1 1 1 1 PNGase C-terminal domain, mannose-binding module PAW Rad4 PF03835.15 EGC32321.1 - 0.0011 18.7 0.0 0.0023 17.6 0.0 1.5 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Indigoidine_A PF04227.12 EGC32322.1 - 4.6e-123 410.2 0.4 9.6e-123 409.2 0.5 1.5 2 0 0 2 2 2 1 Indigoidine synthase A like protein PfkB PF00294.24 EGC32322.1 - 2.6e-36 125.5 0.0 4.8e-35 121.3 0.0 2.6 2 0 0 2 2 2 1 pfkB family carbohydrate kinase Transferase PF02458.15 EGC32323.1 - 8e-09 34.6 0.0 1.6e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 Transferase family Pkinase PF00069.25 EGC32324.1 - 3.6e-60 203.6 0.0 4.4e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32324.1 - 1.9e-41 142.1 0.0 2.6e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC32324.1 - 7.4e-05 21.7 0.0 0.00014 20.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC32324.1 - 0.00059 19.2 0.0 0.0011 18.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC32324.1 - 0.0022 17.0 0.2 0.0055 15.7 0.2 1.5 1 1 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGC32324.1 - 0.027 14.4 0.0 0.22 11.4 0.0 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC32324.1 - 0.073 12.1 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 TRAM_LAG1_CLN8 PF03798.16 EGC32325.1 - 5e-11 42.7 9.9 6e-11 42.5 9.9 1.1 1 0 0 1 1 1 1 TLC domain DUF3810 PF12725.7 EGC32325.1 - 0.0066 15.8 0.2 0.0076 15.6 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3810) DUF996 PF06195.13 EGC32325.1 - 0.039 14.3 1.6 0.052 13.8 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF996) TRAM_LAG1_CLN8 PF03798.16 EGC32326.1 - 5.6e-37 127.4 35.0 5.6e-37 127.4 35.0 2.0 2 0 0 2 2 2 2 TLC domain Coilin_N PF15862.5 EGC32326.1 - 0.00046 20.0 0.7 0.00067 19.5 0.7 1.3 1 0 0 1 1 1 1 Coilin N-terminus TRAM1 PF08390.11 EGC32326.1 - 0.042 13.5 0.6 0.042 13.5 0.6 2.9 2 0 0 2 2 2 0 TRAM1-like protein Tmemb_9 PF05434.11 EGC32326.1 - 1.2 9.1 4.2 0.51 10.2 0.1 2.1 2 0 0 2 2 2 0 TMEM9 LRR_6 PF13516.6 EGC32327.1 - 1.1e-16 59.3 16.1 0.0028 17.6 0.4 7.9 8 0 0 8 8 8 4 Leucine Rich repeat Ras PF00071.22 EGC32327.1 - 1.7e-12 47.2 0.1 1.7e-12 47.2 0.1 2.3 2 0 0 2 2 2 1 Ras family DDHD PF02862.17 EGC32327.1 - 0.042 14.0 4.0 0.063 13.4 4.0 1.3 1 0 0 1 1 1 0 DDHD domain LRR_8 PF13855.6 EGC32327.1 - 0.052 13.3 12.6 4 7.3 0.9 5.4 5 2 0 5 5 5 0 Leucine rich repeat Baculo_PEP_C PF04513.12 EGC32327.1 - 0.075 13.1 3.4 0.24 11.5 3.4 1.9 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus TnpV PF14198.6 EGC32327.1 - 0.17 11.9 15.6 0.11 12.5 8.6 2.5 1 1 1 2 2 2 0 Transposon-encoded protein TnpV LRR_1 PF00560.33 EGC32327.1 - 0.39 11.4 10.0 1.6e+02 3.5 0.2 6.4 7 0 0 7 7 6 0 Leucine Rich Repeat Gluconate_2-dh3 PF13618.6 EGC32327.1 - 1.1 9.6 5.6 6.2 7.1 4.1 2.6 2 1 1 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 DASH_Dam1 PF08653.10 EGC32327.1 - 1.1 9.1 4.9 1.3 8.9 1.4 2.6 1 1 1 2 2 2 0 DASH complex subunit Dam1 FliT PF05400.13 EGC32327.1 - 1.7 9.5 7.1 1.8 9.4 5.8 1.8 1 1 0 1 1 1 0 Flagellar protein FliT Atg14 PF10186.9 EGC32327.1 - 3.9 6.5 22.7 7.2 5.6 22.7 1.5 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Enolase_N PF03952.16 EGC32327.1 - 4.1 7.6 12.8 1.1 9.5 5.1 3.1 1 1 2 3 3 3 0 Enolase, N-terminal domain LMBR1 PF04791.16 EGC32327.1 - 4.5 6.1 10.8 6.8 5.5 10.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein LRR_4 PF12799.7 EGC32327.1 - 6.7 7.3 17.8 16 6.1 1.3 5.5 4 1 3 7 7 6 0 Leucine Rich repeats (2 copies) DUF2491 PF10679.9 EGC32328.1 - 0.11 11.6 0.2 0.17 11.1 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2491) DUF4064 PF13273.6 EGC32329.1 - 0.042 14.1 0.7 1.6 9.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Nop14 PF04147.12 EGC32329.1 - 7.3 4.7 6.1 8.8 4.4 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family Maf PF02545.14 EGC32330.1 - 2.4e-32 112.1 0.0 2.7e-32 111.9 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein CmcI PF04989.12 EGC32330.1 - 0.029 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Metallophos_C PF14008.6 EGC32331.1 - 3.9e-21 75.7 0.8 3.9e-21 75.7 0.8 2.8 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGC32331.1 - 2.9e-18 66.2 7.2 2.1e-17 63.5 3.2 2.6 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGC32331.1 - 1.5e-14 55.0 0.5 2.7e-14 54.2 0.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 EGC32331.1 - 0.00025 21.1 0.0 0.025 14.7 0.0 2.5 1 1 0 1 1 1 1 Fn3-like domain from Purple Acid Phosphatase HxlR PF01638.17 EGC32331.1 - 0.21 11.5 0.0 0.43 10.5 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF3430 PF11912.8 EGC32332.1 - 0.005 16.9 15.5 0.0064 16.6 15.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Pkinase PF00069.25 EGC32336.1 - 1.4e-76 257.4 0.0 1.7e-76 257.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32336.1 - 3.6e-34 118.2 0.0 5.2e-34 117.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGC32336.1 - 1.8e-14 53.8 0.1 1.8e-14 53.8 0.1 1.8 2 0 0 2 2 2 1 FHA domain Kinase-like PF14531.6 EGC32336.1 - 1.9e-05 24.1 0.0 8.2e-05 22.1 0.0 1.9 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGC32336.1 - 3.4e-05 23.3 0.1 5.2e-05 22.7 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC32336.1 - 5.6e-05 22.1 0.0 0.0013 17.6 0.0 2.0 1 1 1 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC32336.1 - 0.00011 21.3 0.7 0.00016 20.8 0.7 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Yop-YscD_cpl PF16697.5 EGC32336.1 - 0.00064 20.0 0.0 0.0013 19.0 0.0 1.5 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Pox_ser-thr_kin PF05445.11 EGC32336.1 - 0.0094 15.0 1.4 0.013 14.5 1.4 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase WD40 PF00400.32 EGC32337.1 - 5.7e-28 96.6 16.9 2.7e-07 31.2 2.5 6.5 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32337.1 - 1.2e-19 70.4 6.8 2.1e-08 34.4 0.4 4.4 3 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC32337.1 - 1.4e-09 37.4 4.2 0.00096 18.2 0.8 4.6 1 1 2 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein eIF2A PF08662.11 EGC32337.1 - 1.2e-05 25.3 2.0 0.00085 19.3 0.3 2.9 1 1 2 3 3 3 1 Eukaryotic translation initiation factor eIF2A IKI3 PF04762.12 EGC32337.1 - 0.00022 19.4 0.7 0.26 9.2 0.2 2.6 2 0 0 2 2 2 2 IKI3 family PSII_BNR PF14870.6 EGC32337.1 - 0.045 13.0 1.5 0.083 12.1 1.5 1.4 1 0 0 1 1 1 0 Photosynthesis system II assembly factor YCF48 NACHT_N PF17100.5 EGC32338.1 - 0.019 14.8 0.1 0.022 14.6 0.1 1.1 1 0 0 1 1 1 0 N-terminal domain of NWD NACHT-NTPase VCBS PF13517.6 EGC32339.1 - 1.4e-20 73.6 22.9 1.9e-06 28.4 5.9 5.8 3 3 2 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGC32339.1 - 6.1e-05 23.1 20.8 0.44 10.7 0.1 6.3 6 0 0 6 6 6 4 FG-GAP repeat NUDIX PF00293.28 EGC32340.1 - 9.7e-12 45.1 0.0 1.5e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain SpoOE-like PF09388.10 EGC32340.1 - 0.036 14.0 0.0 0.14 12.0 0.0 2.1 2 0 0 2 2 2 0 Spo0E like sporulation regulatory protein Ribosomal_S17_N PF16205.5 EGC32341.1 - 2.1e-27 95.3 1.3 4e-27 94.4 1.3 1.5 1 0 0 1 1 1 1 Ribosomal_S17 N-terminal Ribosomal_S17 PF00366.20 EGC32341.1 - 9.7e-27 92.9 0.6 1.5e-26 92.3 0.6 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S8e PF01201.22 EGC32342.1 - 1.3e-50 171.1 3.2 1.8e-50 170.7 3.2 1.2 1 0 0 1 1 1 1 Ribosomal protein S8e FAM86 PF14904.6 EGC32343.1 - 0.083 13.0 7.9 1.4 9.0 1.4 4.6 3 2 0 3 3 3 0 Family of unknown function TPR_2 PF07719.17 EGC32344.1 - 7.3e-26 88.2 7.5 0.00027 20.8 0.1 6.9 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32344.1 - 3.8e-21 74.0 11.6 7.5e-06 25.5 0.4 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32344.1 - 9.2e-16 57.2 17.6 1.4e-11 43.9 2.0 5.0 3 1 2 5 5 5 4 TPR repeat TPR_8 PF13181.6 EGC32344.1 - 1.5e-11 43.6 13.6 0.015 15.5 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGC32344.1 - 8.1e-10 38.7 0.0 0.00014 21.9 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC32344.1 - 1.4e-09 38.4 0.3 0.0011 19.6 0.0 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32344.1 - 5.5e-09 35.8 0.8 0.0016 18.7 0.0 5.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32344.1 - 3.8e-07 30.3 0.6 0.084 13.2 0.0 4.7 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32344.1 - 2.2e-06 28.0 0.0 3.7 8.6 0.0 4.8 3 1 2 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32344.1 - 3.3e-06 27.5 0.4 0.011 16.3 0.0 4.3 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32344.1 - 0.00048 20.0 1.7 0.78 9.9 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat DUF3808 PF10300.9 EGC32344.1 - 0.036 12.8 0.0 0.036 12.8 0.0 3.4 3 0 0 3 3 1 0 Protein of unknown function (DUF3808) TPR_6 PF13174.6 EGC32344.1 - 0.27 11.9 5.8 15 6.5 0.1 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32344.1 - 1.2 9.1 3.7 14 5.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Fusion_gly PF00523.18 EGC32345.1 - 0.017 13.4 0.3 0.024 12.9 0.3 1.1 1 0 0 1 1 1 0 Fusion glycoprotein F0 LIM PF00412.22 EGC32346.1 - 7.8e-40 134.9 64.2 4.4e-11 42.8 4.0 5.6 5 0 0 5 5 5 5 LIM domain PTEN_C2 PF10409.9 EGC32346.1 - 2.7e-12 46.6 0.1 7e-12 45.3 0.1 1.7 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGC32346.1 - 7e-07 29.1 0.0 2.8e-06 27.2 0.0 2.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC32346.1 - 6.9e-06 25.8 0.0 2.1e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC32346.1 - 0.0032 17.6 0.0 0.0076 16.4 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGC32346.1 - 0.0052 16.8 0.0 0.0091 16.0 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPn PF14671.6 EGC32346.1 - 0.01 16.3 0.0 0.022 15.2 0.0 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half DUF2089 PF09862.9 EGC32346.1 - 0.053 13.6 2.9 17 5.5 0.0 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2089) MRP_L53 PF10780.9 EGC32347.1 - 0.0019 18.3 0.8 0.0037 17.4 0.8 1.5 1 0 0 1 1 1 1 39S ribosomal protein L53/MRP-L53 Coiled PF05710.12 EGC32348.1 - 1.6 9.6 15.2 4.4 8.2 15.2 1.8 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.12 EGC32349.1 - 0.99 10.3 18.6 3.5 8.5 18.6 1.9 1 1 0 1 1 1 0 Coiled coil DUF2057 PF09829.9 EGC32354.1 - 0.00065 19.9 0.2 5.4 7.1 0.0 3.6 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2057) DUF2458 PF10454.9 EGC32354.1 - 0.011 15.4 0.7 2.8 7.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Macoilin PF09726.9 EGC32357.1 - 4.9 5.6 17.1 6 5.3 17.1 1.2 1 0 0 1 1 1 0 Macoilin family zf-C3HC4_3 PF13920.6 EGC32359.1 - 1.2e-06 28.2 5.4 1.9e-06 27.6 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC32359.1 - 2.7e-06 27.1 4.1 2.7e-06 27.1 4.1 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC32359.1 - 4e-05 23.4 10.5 0.00032 20.5 10.5 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32359.1 - 6.9e-05 23.1 8.6 0.0003 21.1 8.7 1.9 1 1 1 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGC32359.1 - 8e-05 22.8 4.0 0.00013 22.1 4.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC32359.1 - 0.00048 20.0 9.6 0.0033 17.3 9.6 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC32359.1 - 0.00096 19.2 1.2 0.0014 18.7 1.2 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC32359.1 - 0.0015 18.7 4.5 0.0015 18.7 4.5 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC32359.1 - 0.0025 17.6 8.2 0.0083 16.0 8.2 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC32359.1 - 0.0075 16.3 10.6 0.085 12.9 7.2 3.2 1 1 1 2 2 2 1 RING-type zinc-finger Rad50_zn_hook PF04423.14 EGC32359.1 - 0.01 15.7 0.0 0.01 15.7 0.0 2.2 2 1 1 3 3 3 0 Rad50 zinc hook motif zf-RING_4 PF14570.6 EGC32359.1 - 0.019 14.7 8.1 0.099 12.5 8.4 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain NTR PF01759.21 EGC32359.1 - 0.023 14.5 0.2 0.032 14.0 0.2 1.2 1 0 0 1 1 1 0 UNC-6/NTR/C345C module DUF2951 PF11166.8 EGC32359.1 - 0.027 14.7 0.4 0.038 14.2 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) CTU2 PF10288.9 EGC32359.1 - 0.14 12.4 2.7 1.5 9.1 0.6 2.2 2 0 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 zinc_ribbon_9 PF14369.6 EGC32359.1 - 0.49 10.7 7.0 0.71 10.2 3.4 2.6 2 1 0 2 2 2 0 zinc-ribbon DZR PF12773.7 EGC32359.1 - 0.63 10.1 6.0 2.7 8.1 6.1 1.9 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 EGC32359.1 - 2 8.4 7.4 40 4.2 7.3 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein FYVE PF01363.21 EGC32359.1 - 6.7 6.9 8.6 61 3.9 3.7 3.0 1 1 2 3 3 3 0 FYVE zinc finger AAA_11 PF13086.6 EGC32360.1 - 3.4 7.4 12.9 3.8 7.2 12.9 1.0 1 0 0 1 1 1 0 AAA domain DDHD PF02862.17 EGC32360.1 - 5 7.2 7.8 5.6 7.1 7.8 1.0 1 0 0 1 1 1 0 DDHD domain Nucleo_P87 PF07267.11 EGC32360.1 - 5.7 5.7 12.4 6.2 5.5 12.4 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Cytomega_UL84 PF06284.11 EGC32360.1 - 6.9 5.0 7.5 7.1 5.0 7.5 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein IL4 PF00727.18 EGC32361.1 - 3.4 7.9 7.4 4.3 7.6 0.3 2.6 2 1 1 3 3 3 0 Interleukin 4 MRP-L46 PF11788.8 EGC32362.1 - 1.1e-06 29.3 2.6 1.1e-06 29.3 2.6 3.1 2 2 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.28 EGC32362.1 - 0.00014 21.9 0.0 0.00029 20.9 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain LXG PF04740.12 EGC32362.1 - 0.15 11.8 4.1 0.075 12.7 0.8 2.1 2 0 0 2 2 2 0 LXG domain of WXG superfamily Na_H_Exchanger PF00999.21 EGC32363.1 - 1.2e-60 205.4 42.2 1.5e-60 205.0 42.2 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.12 EGC32363.1 - 5.8e-05 23.0 5.6 5.8e-05 23.0 5.6 2.9 2 2 2 4 4 4 1 Predicted Permease Membrane Region Endotoxin_N PF03945.14 EGC32364.1 - 0.00014 21.7 0.4 0.12 12.0 0.2 2.5 1 1 0 2 2 2 2 delta endotoxin, N-terminal domain Endotoxin_N PF03945.14 EGC32365.1 - 0.008 15.9 3.3 0.066 12.9 0.4 2.3 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain RhoGAP PF00620.27 EGC32366.1 - 1.6e-18 67.0 0.0 4.6e-18 65.5 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.23 EGC32366.1 - 2.8e-11 43.6 0.2 2.8e-11 43.6 0.2 2.1 2 0 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain COMM_domain PF07258.14 EGC32367.1 - 1.8e-14 53.6 1.7 3.3e-14 52.8 1.1 1.8 2 0 0 2 2 2 1 COMM domain HTH_Tnp_ISL3 PF13542.6 EGC32367.1 - 0.03 13.7 0.0 0.072 12.5 0.0 1.6 1 1 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 DHR-2 PF06920.13 EGC32368.1 - 6e-44 150.6 22.8 6e-44 150.6 22.8 3.4 2 1 0 2 2 2 1 Dock homology region 2 F-box-like PF12937.7 EGC32368.1 - 2.9e-07 30.3 1.5 7.9e-07 28.9 1.5 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC32368.1 - 0.00059 19.6 0.5 0.002 18.0 0.5 1.9 1 0 0 1 1 1 1 F-box domain COX6B PF02297.17 EGC32369.1 - 0.11 12.7 4.6 13 6.1 4.6 2.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.9 EGC32369.1 - 0.27 11.6 4.0 0.09 13.1 1.0 1.8 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.10 EGC32369.1 - 1.9 8.6 5.6 2.4 8.3 0.4 2.9 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad10 PF03834.14 EGC32370.1 - 2.8e-39 133.7 1.5 8.5e-39 132.1 0.5 1.9 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_2 PF12826.7 EGC32370.1 - 1.2e-05 25.3 0.0 2.1e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.6 EGC32370.1 - 8.3e-05 23.1 0.0 0.00015 22.3 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EGC32370.1 - 0.012 15.4 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif DUF5532 PF17673.1 EGC32370.1 - 0.043 13.9 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) ubiquitin PF00240.23 EGC32371.1 - 9.9e-10 38.0 2.3 2.3e-08 33.6 0.0 3.4 3 0 0 3 3 3 1 Ubiquitin family Rad60-SLD PF11976.8 EGC32371.1 - 1.6e-08 34.2 0.1 1.6e-07 31.0 0.0 2.7 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like VWA_2 PF13519.6 EGC32371.1 - 7e-07 29.9 0.2 2.7e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Ras PF00071.22 EGC32371.1 - 8.4e-05 22.2 0.1 0.00027 20.6 0.1 1.9 1 0 0 1 1 1 1 Ras family TRAPPC-Trs85 PF12739.7 EGC32371.1 - 0.014 14.4 0.9 0.028 13.4 0.9 1.4 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit VWA PF00092.28 EGC32371.1 - 0.022 15.0 0.1 0.12 12.7 0.0 2.2 3 0 0 3 3 3 0 von Willebrand factor type A domain Mucin PF01456.17 EGC32371.1 - 0.13 12.3 9.8 0.036 14.0 4.1 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein CBS PF00571.28 EGC32372.1 - 5.5e-21 74.8 1.7 4.4e-07 30.3 0.0 3.2 3 0 0 3 3 3 3 CBS domain RBD PF02196.15 EGC32372.1 - 0.02 15.0 0.0 0.096 12.8 0.0 1.9 2 0 0 2 2 2 0 Raf-like Ras-binding domain ACBP PF00887.19 EGC32373.1 - 1.1e-23 83.3 0.1 1.1e-23 83.3 0.1 1.9 2 0 0 2 2 2 1 Acyl CoA binding protein Ank_5 PF13857.6 EGC32373.1 - 6.8e-17 61.3 0.0 2.4e-11 43.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC32373.1 - 1.1e-16 61.0 0.0 1.5e-13 50.9 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC32373.1 - 3.1e-16 59.7 0.1 5.6e-08 33.3 0.0 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGC32373.1 - 1e-12 47.8 0.0 1.5e-05 25.2 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.6 EGC32373.1 - 9.6e-12 44.0 0.1 9.7e-06 25.6 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Taxilin PF09728.9 EGC32374.1 - 9.6e-55 185.9 65.7 9.6e-55 185.9 65.7 2.2 3 0 0 3 3 3 1 Myosin-like coiled-coil protein ERM PF00769.19 EGC32374.1 - 0.0011 18.8 20.0 0.0011 18.8 20.0 3.0 1 1 2 3 3 3 1 Ezrin/radixin/moesin family TMF_DNA_bd PF12329.8 EGC32374.1 - 0.014 15.4 12.5 0.014 15.4 12.5 7.7 4 3 2 7 7 7 0 TATA element modulatory factor 1 DNA binding Takusan PF04822.13 EGC32374.1 - 0.016 15.1 3.2 0.016 15.1 3.2 6.8 4 2 1 5 5 5 0 Takusan YabA PF06156.13 EGC32374.1 - 0.049 14.3 1.6 0.049 14.3 1.6 6.6 1 1 4 5 5 5 0 Initiation control protein YabA ALIX_LYPXL_bnd PF13949.6 EGC32374.1 - 7 5.9 55.9 2.9 7.1 16.9 3.1 1 1 2 3 3 3 0 ALIX V-shaped domain binding to HIV Alg6_Alg8 PF03155.15 EGC32375.1 - 2.3e-162 541.4 33.5 2.7e-162 541.1 33.5 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RWD PF05773.22 EGC32376.1 - 7e-12 45.7 1.9 8.3e-12 45.4 0.3 2.0 2 0 0 2 2 2 1 RWD domain zf-RING_5 PF14634.6 EGC32376.1 - 0.00074 19.4 6.5 0.00074 19.4 6.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC32376.1 - 0.017 15.0 4.1 0.017 15.0 4.1 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32376.1 - 0.02 15.2 4.4 0.02 15.2 4.4 2.7 2 0 0 2 2 2 0 Ring finger domain Nudix_N_2 PF14803.6 EGC32376.1 - 0.022 14.6 5.2 0.089 12.7 0.2 3.2 3 0 0 3 3 3 0 Nudix N-terminal Prok-RING_4 PF14447.6 EGC32376.1 - 0.086 12.7 1.8 0.36 10.7 1.8 2.1 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC32376.1 - 0.17 12.2 2.2 0.61 10.4 2.2 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain DZR PF12773.7 EGC32376.1 - 0.47 10.5 10.8 16 5.6 0.2 3.4 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_UBOX PF13445.6 EGC32376.1 - 1.4 9.1 8.3 0.074 13.1 1.2 2.6 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC32376.1 - 1.7 8.5 9.3 0.72 9.8 5.1 2.6 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC32376.1 - 3 7.8 16.7 0.03 14.2 6.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) p450 PF00067.22 EGC32377.1 - 2.5e-80 270.5 0.1 2.8e-80 270.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2304 PF10066.9 EGC32377.1 - 0.16 12.2 1.4 0.44 10.8 1.4 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2304) Cullin PF00888.22 EGC32378.1 - 1.6e-169 565.5 31.2 2.5e-169 564.8 31.2 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGC32378.1 - 9.3e-27 92.9 3.0 9.3e-27 92.9 3.0 3.6 4 0 0 4 4 4 1 Cullin protein neddylation domain HTH_27 PF13463.6 EGC32378.1 - 0.0049 17.3 0.0 4.8 7.8 0.0 2.6 2 0 0 2 2 2 2 Winged helix DNA-binding domain MarR PF01047.22 EGC32378.1 - 0.0066 16.4 0.2 2.8 7.9 0.1 2.6 2 0 0 2 2 2 2 MarR family TFIIE_alpha PF02002.17 EGC32378.1 - 0.012 15.4 0.4 0.068 13.0 0.1 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit IL28A PF15177.6 EGC32378.1 - 0.054 13.3 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Interleukin-28A Rio2_N PF09202.11 EGC32378.1 - 0.075 13.3 2.8 0.22 11.8 0.0 3.1 4 0 0 4 4 4 0 Rio2, N-terminal E1_FCCH PF16190.5 EGC32378.1 - 0.079 13.2 0.0 0.35 11.1 0.0 2.1 1 0 0 1 1 1 0 Ubiquitin-activating enzyme E1 FCCH domain Rrf2 PF02082.20 EGC32378.1 - 0.13 12.6 0.0 1.9 8.9 0.1 2.7 3 0 0 3 3 3 0 Transcriptional regulator CARD PF00619.21 EGC32378.1 - 0.16 12.0 2.8 2.3 8.3 0.1 3.3 4 0 0 4 4 4 0 Caspase recruitment domain ThiF PF00899.21 EGC32379.1 - 1.1e-35 123.2 0.0 1.8e-35 122.4 0.0 1.4 1 0 0 1 1 1 1 ThiF family Sacchrp_dh_NADP PF03435.18 EGC32379.1 - 0.00078 19.7 0.6 0.0052 17.1 0.6 2.2 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_7 PF13241.6 EGC32379.1 - 0.013 15.9 0.0 0.031 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.16 EGC32379.1 - 0.035 13.8 0.0 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGC32379.1 - 0.16 11.9 0.0 6.5 6.6 0.0 2.3 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_POL_M_15KD PF02150.16 EGC32380.1 - 3.9e-12 45.8 2.8 3.9e-12 45.8 2.8 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.18 EGC32380.1 - 6.6e-11 41.9 3.9 6.6e-11 41.9 3.9 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) zf-ribbon_3 PF13248.6 EGC32380.1 - 0.022 14.1 6.1 0.62 9.5 0.1 3.3 3 0 0 3 3 3 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.12 EGC32380.1 - 0.037 13.6 1.3 0.037 13.6 1.3 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding Lar_restr_allev PF14354.6 EGC32380.1 - 0.043 14.2 2.5 0.043 14.2 2.5 2.4 2 1 0 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS1595 PF12760.7 EGC32380.1 - 0.46 10.5 8.8 0.19 11.7 2.0 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Prim_Zn_Ribbon PF08273.12 EGC32380.1 - 0.78 10.1 0.1 0.78 10.1 0.1 3.0 4 0 0 4 4 4 0 Zinc-binding domain of primase-helicase FF PF01846.19 EGC32381.1 - 0.0022 18.1 4.5 1 9.6 0.2 4.0 3 0 0 3 3 3 2 FF domain Glyoxalase_2 PF12681.7 EGC32381.1 - 0.98 9.4 7.8 0.92 9.4 1.0 3.1 3 0 0 3 3 3 0 Glyoxalase-like domain Peptidase_M22 PF00814.25 EGC32384.1 - 3.4e-72 243.4 0.0 5.2e-72 242.8 0.0 1.3 1 0 0 1 1 1 1 Glycoprotease family GBR_NSP5 PF17580.2 EGC32384.1 - 0.0011 18.8 1.7 0.0011 18.8 1.7 1.8 2 0 0 2 2 2 1 Group B Rotavirus Non-structural protein 5 YycC PF14174.6 EGC32384.1 - 0.0013 18.5 0.0 0.0032 17.2 0.0 1.7 1 0 0 1 1 1 1 YycC-like protein SAGA-Tad1 PF12767.7 EGC32384.1 - 0.011 15.4 0.1 0.021 14.6 0.1 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit FGGY_C PF02782.16 EGC32384.1 - 0.049 13.3 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain COesterase PF00135.28 EGC32385.1 - 4.6e-123 411.8 0.0 5.9e-123 411.4 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC32385.1 - 4e-06 26.8 0.1 2.4e-05 24.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC32385.1 - 0.0026 17.3 0.0 0.0044 16.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Imm25 PF15564.6 EGC32385.1 - 0.0048 16.8 0.2 0.013 15.4 0.1 1.7 2 0 0 2 2 2 1 Immunity protein 25 Hydrolase_4 PF12146.8 EGC32385.1 - 0.022 14.1 0.0 0.035 13.4 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 UCH PF00443.29 EGC32386.1 - 3.2e-46 157.9 0.3 5.2e-46 157.2 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP_var PF17807.1 EGC32386.1 - 1.7e-22 78.9 0.8 1.3e-20 72.9 0.5 2.7 3 0 0 3 3 3 1 Variant UBP zinc finger UBA PF00627.31 EGC32386.1 - 1.1e-16 60.4 0.0 2e-09 37.1 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.19 EGC32386.1 - 7.3e-16 58.3 0.6 6.8e-15 55.1 0.0 2.4 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.6 EGC32386.1 - 8e-12 45.4 0.0 1.8e-11 44.2 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Response_reg PF00072.24 EGC32387.1 - 1.4e-20 73.6 0.2 2.9e-20 72.5 0.2 1.5 1 0 0 1 1 1 1 Response regulator receiver domain TFIIA PF03153.13 EGC32387.1 - 3 7.8 55.3 0.042 13.9 47.8 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit PRIMA1 PF16101.5 EGC32388.1 - 0.0057 16.7 5.6 0.011 15.7 5.6 1.5 1 0 0 1 1 1 1 Proline-rich membrane anchor 1 Glyoxalase PF00903.25 EGC32389.1 - 3.7e-08 33.6 0.0 2.1e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.7 EGC32389.1 - 1.6e-05 24.8 0.1 2.8e-05 24.0 0.1 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 EGC32389.1 - 0.014 15.4 0.2 0.54 10.3 0.1 2.1 2 0 0 2 2 2 0 CppA N-terminal Menin PF05053.13 EGC32390.1 - 0.098 11.0 7.2 0.2 10.0 7.2 1.4 1 0 0 1 1 1 0 Menin TPR_1 PF00515.28 EGC32391.1 - 3.8e-13 48.6 10.6 6.2e-05 22.6 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32391.1 - 1.3e-08 34.3 8.5 0.011 15.8 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32391.1 - 4.4e-06 26.5 0.9 0.042 14.1 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32391.1 - 0.00011 21.9 0.1 0.17 12.0 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32391.1 - 0.00018 22.1 0.0 0.099 13.5 0.0 3.1 1 1 2 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32391.1 - 0.00035 21.0 0.1 0.011 16.2 0.0 2.7 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32391.1 - 0.0019 18.5 1.7 0.048 14.0 0.4 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32391.1 - 0.0031 17.2 1.1 8 6.2 0.0 4.1 3 1 1 4 4 4 2 TPR repeat ANAPC3 PF12895.7 EGC32391.1 - 0.02 15.1 6.4 0.44 10.8 4.1 3.0 2 1 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF3856 PF12968.7 EGC32391.1 - 0.039 14.0 0.2 1.7 8.7 0.1 2.5 1 1 1 2 2 2 0 Domain of Unknown Function (DUF3856) Fis1_TPR_C PF14853.6 EGC32391.1 - 0.091 12.9 0.9 1.2 9.2 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat FapA PF03961.13 EGC32391.1 - 0.12 10.9 10.2 0.32 9.6 4.6 2.2 1 1 0 2 2 2 0 Flagellar Assembly Protein A TPR_17 PF13431.6 EGC32391.1 - 0.32 11.5 7.6 1.5 9.4 0.0 4.3 4 1 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGC32391.1 - 0.39 10.8 6.2 8 6.6 0.3 3.4 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain RPN7 PF10602.9 EGC32391.1 - 2.6 7.7 10.3 0.14 11.9 0.8 2.6 2 1 0 2 2 2 0 26S proteasome subunit RPN7 CobT PF06213.12 EGC32392.1 - 5.2 6.4 21.9 10 5.4 21.9 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Rad60-SLD PF11976.8 EGC32393.1 - 2.2e-22 78.6 0.1 2.7e-22 78.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC32393.1 - 8.8e-12 44.6 0.0 1.1e-11 44.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family FYVE PF01363.21 EGC32394.1 - 1.5e-21 76.3 14.2 1.7e-21 76.1 14.2 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.16 EGC32394.1 - 0.21 11.8 13.4 0.32 11.2 13.4 1.4 1 1 0 1 1 1 0 FYVE-type zinc finger TMEM154 PF15102.6 EGC32395.1 - 0.00016 21.6 0.5 0.00032 20.6 0.5 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF4275 PF14101.6 EGC32396.1 - 0.017 15.2 2.3 0.065 13.4 2.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4275) Methyltransf_11 PF08241.12 EGC32397.1 - 2.4e-19 69.8 0.0 4.4e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32397.1 - 3.9e-17 62.7 0.0 9.5e-17 61.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC32397.1 - 3.4e-13 49.5 0.0 1.7e-12 47.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGC32397.1 - 8.1e-13 48.4 0.2 3.8e-12 46.2 0.1 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC32397.1 - 4.5e-10 40.2 0.1 1.6e-09 38.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC32397.1 - 3.2e-07 30.3 0.0 5.7e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGC32397.1 - 0.00022 21.1 0.0 0.00047 20.1 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_33 PF10017.9 EGC32397.1 - 0.088 11.9 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 Histidine-specific methyltransferase, SAM-dependent Keratin_assoc PF09775.9 EGC32398.1 - 9.5e-24 83.5 11.0 1.8e-23 82.6 11.0 1.4 1 1 0 1 1 1 1 Keratinocyte-associated protein 2 DUF3169 PF11368.8 EGC32398.1 - 0.081 12.4 6.3 0.027 14.0 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) Stomagen PF16851.5 EGC32399.1 - 0.0081 16.1 0.1 0.0081 16.1 0.1 2.4 3 0 0 3 3 3 1 Stomagen SR-25 PF10500.9 EGC32400.1 - 0.049 13.2 0.6 0.11 12.1 0.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TPR_1 PF00515.28 EGC32401.1 - 3.4e-33 112.1 27.9 6.3e-06 25.8 0.5 9.3 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32401.1 - 1.2e-31 106.2 13.6 0.00011 22.1 0.4 9.5 8 1 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32401.1 - 1.8e-28 97.9 15.3 7.8e-05 22.3 0.1 8.1 7 2 2 9 9 9 6 TPR repeat TPR_16 PF13432.6 EGC32401.1 - 5.8e-23 81.3 0.0 0.00028 21.4 0.0 6.5 5 1 1 6 6 6 5 Tetratricopeptide repeat DnaJ PF00226.31 EGC32401.1 - 2.7e-22 78.7 14.9 3.1e-22 78.5 6.8 3.4 3 0 0 3 3 3 1 DnaJ domain TPR_8 PF13181.6 EGC32401.1 - 3.6e-21 73.6 31.2 0.0003 20.8 0.0 9.5 9 2 2 11 11 10 6 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32401.1 - 1e-17 63.3 0.2 0.00058 20.5 0.0 7.8 5 2 3 8 8 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32401.1 - 3.2e-16 59.6 6.0 3.2e-05 24.3 0.1 6.3 5 2 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32401.1 - 4.4e-15 55.7 10.7 8.3e-05 22.8 0.0 7.7 4 2 2 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32401.1 - 6.1e-13 48.2 3.6 0.0052 17.1 0.0 7.0 8 0 0 8 8 6 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC32401.1 - 1e-12 48.0 0.0 0.00024 21.2 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC32401.1 - 1.7e-09 37.8 9.5 0.0021 18.3 0.0 5.5 3 2 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC32401.1 - 4.5e-09 36.4 10.5 0.11 13.2 0.0 8.2 8 1 2 10 10 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32401.1 - 1.1e-07 31.3 2.2 0.057 13.5 0.0 6.1 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_20 PF14561.6 EGC32401.1 - 1e-06 28.9 7.0 0.012 15.9 0.2 5.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGC32401.1 - 2.1e-06 27.2 0.4 0.046 12.9 0.1 4.4 1 1 1 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32401.1 - 1.2e-05 25.0 4.0 15 5.6 0.0 7.0 7 0 0 7 7 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC32401.1 - 3.1e-05 24.0 11.2 0.026 14.6 0.2 6.0 7 0 0 7 7 6 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EGC32401.1 - 0.0015 17.6 25.3 0.0026 16.8 0.2 4.5 1 1 4 5 5 4 3 NMDA receptor-regulated protein 1 Alkyl_sulf_dimr PF14863.6 EGC32401.1 - 0.0016 18.9 3.4 1.4 9.3 0.0 4.0 3 1 1 4 4 4 1 Alkyl sulfatase dimerisation DUF3856 PF12968.7 EGC32401.1 - 0.002 18.2 1.4 2.2 8.4 0.0 5.3 3 2 1 4 4 4 1 Domain of Unknown Function (DUF3856) Rapsyn_N PF10579.9 EGC32401.1 - 0.035 14.2 0.5 14 5.8 0.0 3.5 3 0 0 3 3 3 0 Rapsyn N-terminal myristoylation and linker region MIT PF04212.18 EGC32401.1 - 0.078 13.1 20.1 0.63 10.2 0.1 7.0 8 0 0 8 8 8 0 MIT (microtubule interacting and transport) domain ANAPC5 PF12862.7 EGC32401.1 - 0.11 12.6 1.6 26 5.0 0.0 4.1 4 1 0 4 4 3 0 Anaphase-promoting complex subunit 5 Spectrin PF00435.21 EGC32401.1 - 0.22 12.1 7.7 1.2 9.7 0.6 3.1 3 0 0 3 3 2 0 Spectrin repeat FRB_dom PF08771.11 EGC32401.1 - 7.1 7.1 8.2 4.4 7.8 0.1 3.7 3 1 0 3 3 3 0 FKBP12-rapamycin binding domain UPF0122 PF04297.14 EGC32401.1 - 8.4 6.7 11.6 0.15 12.3 0.7 3.3 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like E1_dh PF00676.20 EGC32402.1 - 8.8e-95 317.1 0.1 1.2e-94 316.7 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component DXP_synthase_N PF13292.6 EGC32402.1 - 0.0067 15.7 0.0 0.022 14.0 0.0 1.8 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase TPR_1 PF00515.28 EGC32404.1 - 3.9e-29 99.2 6.2 8.7e-08 31.7 0.4 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32404.1 - 5.5e-21 72.9 13.9 0.00011 22.0 0.2 9.2 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32404.1 - 2.4e-16 59.8 2.8 6.7e-10 39.1 0.2 4.7 5 1 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32404.1 - 2.5e-16 58.5 14.8 0.0035 17.4 0.0 8.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32404.1 - 2.3e-11 42.9 0.3 0.022 14.8 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32404.1 - 9.3e-09 35.4 0.0 4.1 8.5 0.0 4.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32404.1 - 1.8e-08 33.9 0.0 0.021 14.5 0.0 4.9 3 1 1 4 4 4 3 TPR repeat TPR_19 PF14559.6 EGC32404.1 - 4.8e-08 33.4 0.1 0.2 12.2 0.0 5.5 6 1 1 7 7 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32404.1 - 4.9e-08 32.6 0.7 0.093 12.6 0.0 4.5 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC32404.1 - 4.9e-07 29.9 34.3 1e-05 25.7 6.2 6.6 5 3 1 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGC32404.1 - 2.4e-05 24.9 0.0 0.06 14.0 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC32404.1 - 3.8e-05 24.0 4.6 6.1 7.7 0.1 6.2 7 0 0 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC32404.1 - 0.00014 22.0 0.0 0.003 17.7 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32404.1 - 0.00017 21.7 14.1 2 9.0 0.0 7.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_3 PF07720.12 EGC32404.1 - 0.0015 18.5 3.6 0.018 15.0 0.1 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC32404.1 - 0.0034 17.4 2.5 0.24 11.5 0.7 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat PPR PF01535.20 EGC32404.1 - 0.2 12.0 2.4 44 4.6 0.1 4.1 4 0 0 4 4 4 0 PPR repeat Clr2 PF10383.9 EGC32404.1 - 0.46 11.3 2.4 6.3 7.6 0.5 2.8 2 0 0 2 2 2 0 Transcription-silencing protein Clr2 NicO PF03824.16 EGC32406.1 - 0.004 16.6 8.8 0.004 16.6 8.8 1.5 2 0 0 2 2 2 1 High-affinity nickel-transport protein RAMP PF04901.13 EGC32406.1 - 0.0068 16.4 0.3 0.0068 16.4 0.3 1.8 2 0 0 2 2 2 1 Receptor activity modifying family YfiO PF13525.6 EGC32407.1 - 0.012 15.3 0.0 0.013 15.2 0.0 1.0 1 0 0 1 1 1 0 Outer membrane lipoprotein Atx10homo_assoc PF09759.9 EGC32408.1 - 2.2e-36 123.8 2.4 2.2e-36 123.8 2.4 3.9 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Pkinase_Tyr PF07714.17 EGC32411.1 - 1.6e-60 204.6 0.0 2.5e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC32411.1 - 4.2e-54 183.7 0.0 8.5e-54 182.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC32411.1 - 1.8e-08 33.6 0.1 4.1e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Fungal protein kinase Filamin PF00630.19 EGC32411.1 - 6.1e-07 30.2 0.1 1.9e-06 28.6 0.1 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat FTA2 PF13095.6 EGC32411.1 - 0.0067 16.1 0.0 1.4 8.5 0.0 2.6 2 0 0 2 2 2 1 Kinetochore Sim4 complex subunit FTA2 Arm PF00514.23 EGC32411.1 - 0.01 15.8 0.1 0.9 9.7 0.0 3.6 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat ubiquitin PF00240.23 EGC32411.1 - 0.019 14.7 1.4 1.2 9.0 0.0 3.4 3 0 0 3 3 3 0 Ubiquitin family Ubiquitin_2 PF14560.6 EGC32411.1 - 0.037 14.5 0.2 0.17 12.4 0.2 2.2 1 0 0 1 1 1 0 Ubiquitin-like domain Kinase-like PF14531.6 EGC32411.1 - 0.083 12.2 0.0 0.27 10.5 0.0 1.7 2 0 0 2 2 2 0 Kinase-like APH PF01636.23 EGC32411.1 - 0.18 11.7 0.0 0.31 10.9 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sina PF03145.16 EGC32412.1 - 4.6e-06 26.7 4.6 4.6e-06 26.7 4.6 2.0 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC32412.1 - 0.00038 20.2 8.8 0.00038 20.2 8.8 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC32412.1 - 0.00044 20.1 11.0 0.00044 20.1 11.0 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC32412.1 - 0.0019 18.0 14.3 0.0019 18.0 14.3 3.6 2 2 1 3 3 3 1 Prokaryotic RING finger family 4 zf-TRAF_2 PF15965.5 EGC32412.1 - 0.005 17.3 12.9 0.005 17.3 12.9 2.2 2 0 0 2 2 2 1 TRAF-like zinc-finger zf-TRAF PF02176.18 EGC32412.1 - 0.011 16.3 14.9 0.03 15.0 5.4 3.5 3 1 2 5 5 5 0 TRAF-type zinc finger zf-RING_UBOX PF13445.6 EGC32412.1 - 0.032 14.2 3.8 0.032 14.2 3.8 3.8 3 1 1 4 4 4 0 RING-type zinc-finger STAT_int PF02865.17 EGC32412.1 - 0.058 13.8 0.4 5 7.6 0.1 2.2 2 0 0 2 2 2 0 STAT protein, protein interaction domain VasL PF12486.8 EGC32412.1 - 0.069 13.0 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Type VI secretion system, EvfB, or VasL YacG PF03884.14 EGC32412.1 - 1.9 8.2 21.7 0.38 10.5 5.1 3.6 3 0 0 3 3 3 0 DNA gyrase inhibitor YacG Methyltransf_2 PF00891.18 EGC32413.1 - 2.5e-41 141.3 0.0 3.4e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGC32413.1 - 0.00047 20.1 0.0 0.00095 19.1 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_12 PF08242.12 EGC32413.1 - 0.013 16.2 0.0 0.063 14.0 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain HTH_23 PF13384.6 EGC32413.1 - 0.025 14.4 0.0 0.057 13.2 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Methyltransf_31 PF13847.6 EGC32413.1 - 0.037 13.8 0.0 6.5 6.5 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain HTH_28 PF13518.6 EGC32413.1 - 0.052 13.7 0.0 0.13 12.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EGC32413.1 - 0.056 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Sigma70_r4_2 PF08281.12 EGC32413.1 - 0.073 12.8 0.0 0.14 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 Methyltransf_11 PF08241.12 EGC32413.1 - 0.12 13.1 0.0 1.6 9.4 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Cpn60_TCP1 PF00118.24 EGC32414.1 - 8.1e-33 113.8 0.7 2.5e-18 66.0 0.0 2.1 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family FAM176 PF14851.6 EGC32414.1 - 1.1 8.9 7.0 0.094 12.4 0.3 2.5 3 0 0 3 3 3 0 FAM176 family Acyl_transf_1 PF00698.21 EGC32415.1 - 1e-26 94.2 0.0 6.5e-17 62.0 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain Njmu-R1 PF15053.6 EGC32415.1 - 0.017 14.2 1.2 0.036 13.2 1.2 1.6 1 1 0 1 1 1 0 Mjmu-R1-like protein family VPS13 PF16908.5 EGC32416.1 - 1.2e-48 166.0 12.6 4e-31 108.6 1.7 5.3 4 0 0 4 4 4 3 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGC32416.1 - 1.4e-46 158.5 9.4 7.9e-44 149.5 3.2 3.0 2 0 0 2 2 2 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGC32416.1 - 6.8e-41 140.4 7.9 6.8e-41 140.4 7.9 5.3 6 0 0 6 6 6 1 SHR-binding domain of vacuolar-sorting associated protein 13 Chorein_N PF12624.7 EGC32416.1 - 7.8e-22 77.6 0.1 7.8e-22 77.6 0.1 3.9 4 0 0 4 4 4 1 N-terminal region of Chorein or VPS13 VPS13_mid_rpt PF16910.5 EGC32416.1 - 2.5e-17 63.1 0.4 4.2e-14 52.5 0.0 9.5 11 0 0 11 11 11 2 Repeating coiled region of VPS13 ATG_C PF09333.11 EGC32416.1 - 5.1e-06 26.7 0.0 1.8e-05 25.0 0.0 1.9 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain NeA_P2 PF12312.8 EGC32416.1 - 0.62 9.5 2.3 2.1 7.8 0.2 2.3 2 0 0 2 2 2 0 Nepovirus subgroup A polyprotein TIG PF01833.24 EGC32417.1 - 1.1e-05 25.4 11.5 0.00019 21.5 5.4 2.8 1 1 1 2 2 2 2 IPT/TIG domain Neocarzinostat PF00960.18 EGC32417.1 - 0.063 13.3 0.8 1.9 8.5 0.2 2.6 2 0 0 2 2 2 0 Neocarzinostatin family Sina PF03145.16 EGC32418.1 - 2.4e-07 30.9 1.3 3.4e-07 30.4 1.3 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-TRAF PF02176.18 EGC32418.1 - 1.3e-06 29.0 19.1 0.00028 21.5 1.7 4.1 3 1 2 5 5 5 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC32418.1 - 1.3e-05 25.5 4.9 1.3e-05 25.5 4.9 2.0 1 1 1 2 2 1 1 TRAF-like zinc-finger Prok-RING_4 PF14447.6 EGC32418.1 - 0.00011 21.9 8.0 0.00011 21.9 8.0 2.4 3 0 0 3 3 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC32418.1 - 0.00023 21.3 12.9 0.00023 21.3 12.9 3.2 3 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGC32418.1 - 0.00025 21.0 10.1 0.00025 21.0 10.1 2.3 2 1 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC32418.1 - 0.00037 20.4 8.7 0.00037 20.4 8.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC32418.1 - 0.00042 20.1 8.6 0.00042 20.1 8.6 2.8 1 1 2 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC32418.1 - 0.00094 19.0 11.8 0.00094 19.0 11.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32418.1 - 0.019 15.3 10.7 0.019 15.3 10.7 2.9 2 1 1 3 3 2 0 Ring finger domain zf-U11-48K PF05253.12 EGC32418.1 - 0.026 14.5 1.4 0.23 11.4 0.3 3.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Bacillus_HBL PF05791.11 EGC32418.1 - 0.081 12.7 0.1 0.13 12.1 0.1 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) betaPIX_CC PF16523.5 EGC32418.1 - 0.19 11.6 2.0 0.86 9.5 0.8 2.2 1 1 1 2 2 2 0 betaPIX coiled coil zf-ACC PF17848.1 EGC32418.1 - 0.2 11.8 0.0 0.2 11.8 0.0 5.2 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain zinc_ribbon_4 PF13717.6 EGC32418.1 - 1.1 9.3 7.4 6.9 6.7 0.1 3.4 3 0 0 3 3 2 0 zinc-ribbon domain zf_UBZ PF18439.1 EGC32418.1 - 1.1 8.9 5.4 12 5.6 0.2 4.1 4 0 0 4 4 4 0 Ubiquitin-Binding Zinc Finger Rtf2 PF04641.12 EGC32418.1 - 1.8 7.9 5.7 10 5.4 5.7 2.0 1 1 0 1 1 1 0 Rtf2 RING-finger Sas6_CC PF18594.1 EGC32418.1 - 2.2 8.1 7.1 0.19 11.5 1.9 2.0 2 0 0 2 2 2 0 Sas6/XLF/XRCC4 coiled-coil domain FA_desaturase PF00487.24 EGC32419.1 - 4e-20 72.7 18.0 4e-20 72.7 18.0 1.5 2 0 0 2 2 2 1 Fatty acid desaturase Lipid_DES PF08557.10 EGC32419.1 - 0.0046 16.4 0.2 0.0085 15.6 0.2 1.4 1 0 0 1 1 1 1 Sphingolipid Delta4-desaturase (DES) SPX PF03105.19 EGC32420.1 - 1.5e-17 64.6 16.7 7.3e-09 36.0 4.3 3.0 1 1 2 3 3 3 2 SPX domain DUF1874 PF08960.10 EGC32420.1 - 0.011 15.9 0.5 0.025 14.7 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1874) Pkinase PF00069.25 EGC32422.1 - 1.6e-23 83.5 7.1 1.6e-23 83.5 7.1 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32422.1 - 5.5e-12 45.5 1.7 9.6e-12 44.7 1.7 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC32422.1 - 0.00014 21.3 0.1 0.00025 20.5 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC32422.1 - 0.00054 18.8 0.1 0.0011 17.8 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGC32422.1 - 0.013 15.4 0.0 0.38 10.6 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family DnaB_2 PF07261.11 EGC32422.1 - 0.017 14.9 2.7 0.06 13.1 0.5 3.1 2 0 0 2 2 2 0 Replication initiation and membrane attachment Peptidase_M8 PF01457.16 EGC32423.1 - 6.1e-71 239.7 11.4 9.7e-71 239.0 11.4 1.2 1 0 0 1 1 1 1 Leishmanolysin CpxA_peri PF16527.5 EGC32423.1 - 0.53 10.7 1.8 20 5.6 0.0 2.3 2 0 0 2 2 2 0 Two-component sensor protein CpxA, periplasmic domain Upf2 PF04050.14 EGC32424.1 - 6.2e-11 43.2 2.6 6.2e-11 43.2 2.6 7.1 4 1 2 6 6 6 1 Up-frameshift suppressor 2 Sec7_N PF12783.7 EGC32424.1 - 0.04 13.8 0.2 0.16 11.8 0.2 2.0 1 0 0 1 1 1 0 Guanine nucleotide exchange factor in Golgi transport N-terminal EMC3_TMCO1 PF01956.16 EGC32424.1 - 6.5 6.5 9.6 0.96 9.2 1.6 3.2 2 1 1 3 3 3 0 Integral membrane protein EMC3/TMCO1-like Mad3_BUB1_I PF08311.12 EGC32425.1 - 1.6e-42 144.4 2.1 4.7e-42 142.9 2.1 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 Mad3_BUB1_I_2 PF17014.5 EGC32425.1 - 5.5e-05 23.3 3.7 6.2e-05 23.1 1.0 2.5 2 0 0 2 2 2 1 Putative Mad3/BUB1 like region 1 protein TPR_8 PF13181.6 EGC32425.1 - 0.002 18.2 0.3 0.0075 16.4 0.3 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32425.1 - 0.004 17.2 0.3 0.009 16.1 0.3 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat Mad3_BUB1_II PF08171.11 EGC32425.1 - 0.017 15.3 0.4 0.017 15.3 0.4 4.5 5 0 0 5 5 5 0 Mad3/BUB1 homology region 2 TPR_1 PF00515.28 EGC32425.1 - 0.029 14.2 1.0 0.065 13.1 1.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat 3HCDH PF00725.22 EGC32425.1 - 0.2 12.3 0.0 0.66 10.6 0.0 1.9 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain FNIP PF05725.12 EGC32426.1 - 1.1e-54 182.3 41.6 3e-14 52.9 0.2 8.6 6 2 1 8 8 8 8 FNIP Repeat IBR PF01485.21 EGC32427.1 - 4e-17 62.2 41.6 7.6e-12 45.3 3.0 4.6 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain CUE PF02845.16 EGC32427.1 - 3.8e-11 42.5 0.3 7.9e-11 41.5 0.3 1.6 1 0 0 1 1 1 1 CUE domain zf-C3HC4 PF00097.25 EGC32427.1 - 0.00014 21.7 7.9 0.00014 21.7 7.9 4.9 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32427.1 - 0.00021 21.6 7.6 0.00021 21.6 7.6 4.2 3 2 2 5 5 5 1 Ring finger domain zf-RING_5 PF14634.6 EGC32427.1 - 0.0011 18.8 6.8 0.0011 18.8 6.8 4.0 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC32427.1 - 0.0018 18.0 4.1 0.0018 18.0 4.1 4.5 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Cnd1 PF12717.7 EGC32427.1 - 0.49 10.4 3.7 1.1 9.3 3.7 1.5 1 0 0 1 1 1 0 non-SMC mitotic condensation complex subunit 1 GST_N_2 PF13409.6 EGC32428.1 - 2.1e-22 79.2 0.0 3.8e-22 78.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC32428.1 - 3.9e-11 42.8 0.0 6.6e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC32428.1 - 4.9e-10 39.5 0.2 9e-10 38.7 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC32428.1 - 2e-08 34.3 0.3 4.4e-08 33.2 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC32428.1 - 0.0052 17.2 0.1 0.056 13.9 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC32428.1 - 0.027 14.2 0.5 0.058 13.2 0.5 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Bcl-2_3 PF15286.6 EGC32428.1 - 0.085 13.5 0.1 0.17 12.6 0.1 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like Luteo_P1-P2 PF08467.10 EGC32429.1 - 0.03 13.6 0.0 0.056 12.7 0.0 1.4 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase Translin PF01997.16 EGC32429.1 - 0.055 13.5 0.0 0.17 11.9 0.0 1.8 1 0 0 1 1 1 0 Translin family Matrilin_ccoil PF10393.9 EGC32429.1 - 0.08 12.8 0.7 0.27 11.1 0.7 2.0 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin Osmo_CC PF08946.10 EGC32429.1 - 0.085 13.1 2.4 19 5.6 0.9 3.4 2 1 0 2 2 2 0 Osmosensory transporter coiled coil BAG PF02179.16 EGC32429.1 - 0.11 13.0 2.3 0.3 11.6 2.3 1.8 1 0 0 1 1 1 0 BAG domain MGC-24 PF05283.11 EGC32430.1 - 0.0069 16.8 0.2 0.87 10.0 0.0 2.4 2 0 0 2 2 2 2 Multi-glycosylated core protein 24 (MGC-24), sialomucin 2TM PF13239.6 EGC32430.1 - 0.41 11.0 3.3 0.41 11.0 1.0 2.0 2 0 0 2 2 2 0 2TM domain Cadherin_C_2 PF16492.5 EGC32430.1 - 2.7 8.8 9.1 1.2 10.0 0.1 3.1 3 0 0 3 3 3 0 Cadherin cytoplasmic C-terminal SNase PF00565.17 EGC32431.1 - 3.1e-53 178.8 0.4 3.4e-16 59.7 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.24 EGC32431.1 - 5.8e-10 39.3 0.0 1.2e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Tudor domain IMUP PF15761.5 EGC32431.1 - 5.7 7.7 10.8 4 8.2 6.3 2.6 2 0 0 2 2 2 0 Immortalisation up-regulated protein Methyltransf_8 PF05148.15 EGC32432.1 - 1.1e-79 267.4 0.8 1.2e-79 267.2 0.8 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.12 EGC32432.1 - 2.2e-07 31.4 0.1 2.2e-06 28.2 0.1 2.3 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC32432.1 - 7.9e-06 25.5 0.4 0.00023 20.8 0.1 2.1 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGC32432.1 - 5.2e-05 23.1 0.4 0.23 11.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32432.1 - 0.0001 22.9 0.1 0.019 15.6 0.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGC32432.1 - 0.0043 16.7 0.1 0.0067 16.0 0.1 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EGC32432.1 - 0.012 15.6 0.0 0.034 14.1 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.18 EGC32432.1 - 0.048 13.0 0.1 6.5 6.0 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.7 EGC32432.1 - 0.1 12.5 0.1 0.27 11.2 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.12 EGC32433.1 - 1.7e-06 28.5 6.3 0.024 15.3 0.8 4.3 3 2 0 3 3 3 2 Sel1 repeat TPR_6 PF13174.6 EGC32433.1 - 0.002 18.7 0.1 2.9 8.7 0.1 3.3 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32433.1 - 0.0073 16.1 1.2 0.0073 16.1 1.2 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32433.1 - 0.016 15.5 1.8 0.022 15.1 0.2 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32433.1 - 0.024 14.7 0.6 0.024 14.7 0.6 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32433.1 - 0.11 12.6 0.2 1 9.5 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32433.1 - 5.6 7.4 10.2 0.88 9.9 0.2 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF3007 PF11460.8 EGC32434.1 - 3.1 8.1 6.2 0.43 10.9 2.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Presenilin PF01080.17 EGC32434.1 - 7.5 5.2 5.3 9.8 4.8 5.3 1.2 1 0 0 1 1 1 0 Presenilin TAP42 PF04177.12 EGC32435.1 - 2.7e-66 223.9 3.5 3.2e-66 223.7 3.5 1.0 1 0 0 1 1 1 1 TAP42-like family DUF3685 PF12452.8 EGC32435.1 - 0.016 14.9 0.1 0.016 14.9 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) Glyco_hydro_16 PF00722.21 EGC32436.1 - 3.9e-05 23.2 0.1 9e-05 22.0 0.1 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.21 EGC32437.1 - 0.00036 20.1 0.2 0.0007 19.1 0.2 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 PRELI PF04707.14 EGC32438.1 - 2.8e-29 102.0 0.4 3.6e-29 101.6 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family WD40 PF00400.32 EGC32439.1 - 5.1e-34 115.7 23.6 2.2e-05 25.1 1.5 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat F-box-like PF12937.7 EGC32439.1 - 1.3e-10 41.0 0.3 2.8e-10 39.9 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC32439.1 - 3.8e-08 33.0 0.0 7.5e-08 32.1 0.0 1.5 1 0 0 1 1 1 1 F-box domain WD40_like PF17005.5 EGC32439.1 - 4.5e-05 22.9 0.8 0.079 12.3 0.0 3.1 2 1 0 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGC32439.1 - 5.2e-05 23.5 1.6 0.053 13.8 0.1 4.5 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC32439.1 - 0.042 12.5 14.3 1.8 7.1 0.1 5.5 3 2 3 6 6 6 0 Nucleoporin Nup120/160 Histone_H2A_C PF16211.5 EGC32440.1 - 2e-12 46.6 0.1 3.5e-12 45.8 0.1 1.4 1 0 0 1 1 1 1 C-terminus of histone H2A Histone PF00125.24 EGC32440.1 - 8.7e-11 42.3 0.2 1.6e-10 41.5 0.0 1.4 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC32440.1 - 1.5e-08 34.8 0.0 2e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF4534 PF15049.6 EGC32440.1 - 0.062 13.0 0.0 0.081 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4534) TFIIF_beta PF02270.15 EGC32441.1 - 4.4e-21 74.8 0.1 7.9e-21 74.0 0.1 1.4 1 0 0 1 1 1 1 TFIIF, beta subunit HTH domain TFIIF_beta_N PF17683.1 EGC32441.1 - 4.9e-08 33.8 0.1 9.4e-08 32.8 0.1 1.7 1 1 0 1 1 1 1 TFIIF, beta subunit N-terminus Ycf54 PF10674.9 EGC32441.1 - 0.12 12.7 0.1 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2488) OTU PF02338.19 EGC32443.1 - 2e-16 60.6 0.2 2e-16 60.6 0.2 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.9 EGC32443.1 - 0.00092 18.7 3.3 0.0049 16.3 1.1 3.3 2 2 1 3 3 3 2 Peptidase C65 Otubain UBA_4 PF14555.6 EGC32443.1 - 0.003 17.4 0.0 0.0063 16.3 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain CUE PF02845.16 EGC32443.1 - 0.014 15.1 0.8 0.032 13.9 0.1 2.0 2 0 0 2 2 2 0 CUE domain SSP160 PF06933.11 EGC32443.1 - 0.57 8.3 21.4 0.027 12.7 11.4 2.6 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC32443.1 - 0.63 10.0 23.3 0.34 10.9 18.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Hydin_ADK PF17213.3 EGC32443.1 - 0.69 10.2 14.7 0.12 12.6 10.1 1.9 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DUF3439 PF11921.8 EGC32443.1 - 1.4 8.9 17.6 38 4.3 17.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mcl1_mid PF12341.8 EGC32444.1 - 6.8e-68 229.2 0.7 6.8e-68 229.2 0.7 1.5 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40 PF00400.32 EGC32444.1 - 4.7e-11 43.1 10.3 7.3e-05 23.5 0.5 6.1 5 1 0 5 5 5 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32444.1 - 1.6e-09 37.9 0.0 5.2e-05 23.5 0.0 4.0 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain TPR_1 PF00515.28 EGC32444.1 - 0.15 12.0 0.6 0.42 10.5 0.6 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat CDC45 PF02724.14 EGC32445.1 - 0.48 8.6 15.7 0.53 8.5 15.7 1.0 1 0 0 1 1 1 0 CDC45-like protein Smg4_UPF3 PF03467.15 EGC32446.1 - 9.3e-14 51.8 15.7 9.3e-14 51.8 15.7 3.2 2 2 0 2 2 2 1 Smg-4/UPF3 family UPF0172 PF03665.13 EGC32446.1 - 0.49 10.4 0.0 0.49 10.4 0.0 2.1 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0172) COesterase PF00135.28 EGC32447.1 - 7e-18 64.8 0.1 1.6e-17 63.6 0.1 1.4 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC32447.1 - 1.2e-11 44.9 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC32447.1 - 4.1e-07 29.5 0.2 3.6e-05 23.1 0.2 2.7 2 1 0 2 2 2 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC32447.1 - 8.4e-05 22.1 0.2 0.19 11.1 0.0 2.6 2 1 0 2 2 2 2 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EGC32447.1 - 0.00031 19.7 0.8 0.00047 19.1 0.8 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Abhydrolase_6 PF12697.7 EGC32447.1 - 0.00036 21.2 0.0 0.00046 20.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EGC32447.1 - 0.039 12.9 0.0 0.07 12.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EGC32447.1 - 0.039 13.6 0.2 0.096 12.3 0.2 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold DUF2974 PF11187.8 EGC32447.1 - 0.082 12.4 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Thioesterase PF00975.20 EGC32447.1 - 0.084 13.0 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain PAF-AH_p_II PF03403.13 EGC32447.1 - 0.14 10.6 0.2 1.2 7.6 0.0 2.0 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II CBM49 PF09478.10 EGC32448.1 - 1.3e-19 70.3 0.2 1.6e-19 70.0 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 UbiA PF01040.18 EGC32449.1 - 5.7e-14 52.0 16.1 8.5e-14 51.4 16.1 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MCM PF00493.23 EGC32451.1 - 1e-101 338.7 0.1 2e-101 337.8 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGC32451.1 - 2.7e-38 130.6 0.1 5.2e-38 129.7 0.1 1.5 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC32451.1 - 3.3e-25 88.3 2.2 1.3e-24 86.4 1.2 2.5 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGC32451.1 - 2.1e-13 50.7 0.2 2.1e-13 50.7 0.2 3.3 3 1 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGC32451.1 - 1.9e-08 33.9 0.0 4.8e-07 29.4 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC32451.1 - 2.8e-06 27.4 0.5 9.7e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGC32451.1 - 1.2e-05 25.2 0.0 0.0026 17.6 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MCM2_N PF12619.8 EGC32451.1 - 0.00051 20.4 34.6 0.00051 20.4 34.6 3.0 2 1 0 3 3 2 1 Mini-chromosome maintenance protein 2 AAA_lid_2 PF17863.1 EGC32451.1 - 0.024 14.5 0.1 0.066 13.1 0.1 1.7 1 0 0 1 1 1 0 AAA lid domain Sigma54_activat PF00158.26 EGC32451.1 - 0.026 14.2 0.0 1.6 8.4 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.29 EGC32451.1 - 0.29 11.6 2.2 0.94 9.9 0.1 3.1 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Shisa PF13908.6 EGC32452.1 - 0.0088 16.3 5.6 0.018 15.3 5.6 1.6 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator SARAF PF06682.12 EGC32452.1 - 0.059 13.0 6.0 0.1 12.3 6.0 1.5 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis DUF3169 PF11368.8 EGC32452.1 - 0.089 12.3 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Ac110_PIF PF07280.11 EGC32452.1 - 5.6 6.8 7.9 0.82 9.5 3.3 2.1 2 0 0 2 2 2 0 Per os infectivity factor AC110 RNA_pol_Rpb4 PF03874.16 EGC32454.1 - 1.5e-13 51.1 2.8 9.2e-13 48.6 2.8 1.8 1 1 0 1 1 1 1 RNA polymerase Rpb4 DUF2757 PF10955.8 EGC32454.1 - 0.0054 17.0 0.2 0.013 15.8 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2757) Glyco_hydro_38N PF01074.22 EGC32455.1 - 5.8e-99 331.1 1.4 9.1e-99 330.5 1.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGC32455.1 - 2.3e-39 135.7 1.0 4.4e-39 134.8 1.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGC32455.1 - 3.2e-20 72.1 0.2 8.6e-20 70.7 0.2 1.8 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGC32455.1 - 0.0016 18.5 0.0 0.0038 17.3 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGC32455.1 - 0.0043 16.3 0.0 0.0088 15.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Mo25 PF08569.11 EGC32455.1 - 0.036 13.4 0.0 0.066 12.6 0.0 1.3 1 0 0 1 1 1 0 Mo25-like Brix PF04427.18 EGC32457.1 - 2.6e-38 132.1 0.2 3.7e-38 131.6 0.2 1.2 1 0 0 1 1 1 1 Brix domain EssA PF10661.9 EGC32457.1 - 0.05 13.4 1.2 0.098 12.5 1.2 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA polyprenyl_synt PF00348.17 EGC32459.1 - 2.8e-77 259.3 0.0 3.3e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase polyprenyl_synt PF00348.17 EGC32460.1 - 9e-77 257.6 0.0 1.1e-76 257.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase HMG-CoA_red PF00368.18 EGC32461.1 - 1.2e-148 495.0 2.8 1.4e-148 494.8 2.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase DUF4100 PF13352.6 EGC32461.1 - 0.65 9.7 2.9 0.99 9.1 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4100) NUDIX PF00293.28 EGC32462.1 - 1.5e-10 41.2 0.0 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain AP3D1 PF06375.11 EGC32462.1 - 0.00076 19.8 4.7 0.00076 19.8 4.7 2.7 3 0 0 3 3 3 2 AP-3 complex subunit delta-1 Laminin_G_3 PF13385.6 EGC32463.1 - 1.8e-09 37.9 0.3 1.8e-09 37.9 0.3 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily Arm PF00514.23 EGC32463.1 - 0.05 13.7 1.1 2.4e+02 2.0 0.0 5.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat RasGAP PF00616.19 EGC32464.1 - 2.4e-57 194.0 1.2 2.4e-57 194.0 1.2 2.6 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGC32464.1 - 1.6e-26 93.1 8.1 1.6e-26 93.1 8.1 2.1 2 0 0 2 2 2 1 RasGAP C-terminus Latarcin PF10279.9 EGC32464.1 - 0.23 11.9 3.4 1.5 9.3 2.1 2.7 1 1 1 2 2 2 0 Latarcin precursor Abhydrolase_1 PF00561.20 EGC32465.1 - 1.9e-31 109.6 0.0 3e-31 109.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC32465.1 - 1.8e-11 43.8 0.0 3.8e-11 42.7 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC32465.1 - 5e-08 33.8 0.0 8e-08 33.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGC32465.1 - 0.0027 17.2 0.0 0.92 8.9 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.12 EGC32465.1 - 0.0061 15.4 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 His_Phos_1 PF00300.22 EGC32467.1 - 6.3e-26 91.3 0.0 4.3e-20 72.2 0.0 3.8 4 0 0 4 4 4 3 Histidine phosphatase superfamily (branch 1) WD40 PF00400.32 EGC32468.1 - 1.3e-29 101.8 17.0 8.7e-09 35.9 0.1 7.7 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32468.1 - 1.4e-13 50.9 0.2 0.00014 22.0 0.0 5.0 3 1 1 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC32468.1 - 1.6e-06 28.1 3.1 0.0042 17.0 0.5 3.1 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGC32468.1 - 1e-05 25.0 1.0 5.3e-05 22.7 1.1 2.0 2 0 0 2 2 2 1 WD40-like domain DivIC PF04977.15 EGC32468.1 - 0.0014 18.4 0.9 0.0026 17.5 0.9 1.4 1 0 0 1 1 1 1 Septum formation initiator FlaC_arch PF05377.11 EGC32468.1 - 0.004 17.5 1.0 0.013 15.8 1.0 1.9 1 1 0 1 1 1 1 Flagella accessory protein C (FlaC) DPPIV_N PF00930.21 EGC32468.1 - 0.013 14.3 0.3 0.027 13.2 0.3 1.5 1 0 0 1 1 1 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region betaPIX_CC PF16523.5 EGC32468.1 - 0.018 14.8 0.5 3.6 7.5 0.8 2.5 2 0 0 2 2 2 0 betaPIX coiled coil Ge1_WD40 PF16529.5 EGC32468.1 - 0.021 13.8 0.1 1 8.2 0.0 2.9 3 0 0 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF244 PF03112.14 EGC32468.1 - 0.025 14.4 0.5 0.072 12.9 0.5 1.7 1 0 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF PRKG1_interact PF15898.5 EGC32468.1 - 0.05 14.5 2.6 0.1 13.5 2.6 1.5 1 0 0 1 1 1 0 cGMP-dependent protein kinase interacting domain HMMR_C PF15908.5 EGC32468.1 - 0.058 13.7 0.6 12 6.2 0.1 2.3 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor C-terminal bZIP_1 PF00170.21 EGC32468.1 - 0.059 13.5 1.8 0.12 12.5 1.8 1.4 1 0 0 1 1 1 0 bZIP transcription factor Prefoldin_2 PF01920.20 EGC32468.1 - 0.07 13.1 2.1 0.12 12.3 2.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Cep57_CLD_2 PF14197.6 EGC32468.1 - 0.11 12.6 0.3 0.25 11.4 0.3 1.6 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 SRR1 PF07985.12 EGC32469.1 - 4.5e-14 52.2 0.0 6.6e-14 51.7 0.0 1.3 1 0 0 1 1 1 1 SRR1 Ribosomal_S17e PF00833.18 EGC32469.1 - 0.027 14.4 0.1 0.044 13.7 0.1 1.2 1 0 0 1 1 1 0 Ribosomal S17 Acetyltransf_1 PF00583.25 EGC32470.1 - 8e-11 42.2 0.0 1.1e-10 41.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC32470.1 - 8.7e-10 38.9 0.0 1.3e-09 38.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC32470.1 - 7e-07 29.4 0.0 1.1e-06 28.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC32470.1 - 1.7e-06 28.0 0.0 2.5e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.18 EGC32470.1 - 0.0013 18.4 0.1 0.0019 17.9 0.1 1.3 1 0 0 1 1 1 1 MOZ/SAS family UPF0086 PF01868.16 EGC32471.1 - 2.4e-26 91.5 0.0 4.9e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function UPF0086 HSP20 PF00011.21 EGC32473.1 - 2.3e-07 30.9 0.0 3e-07 30.5 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Actin PF00022.19 EGC32474.1 - 1.9e-33 115.7 0.0 2.4e-19 69.3 0.0 2.7 2 1 0 2 2 2 2 Actin CPL PF08144.11 EGC32475.1 - 1.3e-14 54.7 0.3 1.3e-14 54.7 0.3 4.4 5 1 0 5 5 5 1 CPL (NUC119) domain PUF PF00806.19 EGC32475.1 - 0.00033 20.2 3.3 1.5 8.7 0.1 5.0 4 1 0 4 4 4 2 Pumilio-family RNA binding repeat MgtE_N PF03448.17 EGC32475.1 - 0.074 13.7 2.6 2.6 8.7 0.1 4.4 4 1 1 5 5 5 0 MgtE intracellular N domain Oxidored_FMN PF00724.20 EGC32476.1 - 4e-67 226.9 0.0 4.9e-67 226.6 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGC32476.1 - 0.0058 15.8 0.0 0.049 12.7 0.0 2.1 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Big_2 PF02368.18 EGC32478.1 - 9.9e-19 67.0 16.1 0.00011 22.0 0.0 8.4 10 1 0 10 10 10 4 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.6 EGC32478.1 - 0.092 12.5 11.3 0.11 12.3 0.0 5.5 6 0 0 6 6 6 0 Pilus formation protein N terminal region DDE_Tnp_4 PF13359.6 EGC32479.1 - 0.0021 17.7 0.0 0.0031 17.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldedh PF00171.22 EGC32480.1 - 1.1e-08 34.1 0.0 1.2e-08 33.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Fn3_assoc PF13287.6 EGC32482.1 - 0.0085 16.2 0.2 0.017 15.2 0.2 1.5 1 0 0 1 1 1 1 Fn3 associated DRE2_N PF16803.5 EGC32482.1 - 0.031 14.5 0.3 0.066 13.5 0.1 1.6 2 0 0 2 2 2 0 Fe-S cluster assembly protein DRE2 N-terminus GSH-S_ATP PF02955.16 EGC32482.1 - 0.081 12.3 0.1 0.1 12.0 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain tRNA-synt_1c PF00749.21 EGC32483.1 - 1.9e-112 375.2 0.0 2.9e-112 374.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGC32483.1 - 2.5e-57 193.5 0.5 7.1e-57 192.1 0.5 1.8 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.15 EGC32483.1 - 6.4e-55 185.6 3.0 1.2e-54 184.7 3.0 1.5 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.15 EGC32483.1 - 3.4e-12 47.1 1.1 1e-11 45.6 1.1 1.8 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 WD40 PF00400.32 EGC32484.1 - 8.4e-36 121.4 14.6 1.1e-07 32.4 0.3 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32484.1 - 4.8e-10 39.6 0.0 0.079 13.3 0.0 5.1 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain SSP160 PF06933.11 EGC32484.1 - 1.2 7.3 17.1 1.5 6.9 17.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC32484.1 - 3.1 7.8 26.8 5.2 7.1 26.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein vWA-TerF-like PF10138.9 EGC32485.1 - 1.6e-06 28.4 0.0 2e-06 28.1 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC32485.1 - 1.8e-05 25.1 0.0 2.6e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGC32485.1 - 0.00034 20.6 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC32485.1 - 0.00038 21.1 0.0 0.00072 20.2 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Copine PF07002.16 EGC32485.1 - 0.0077 15.7 0.0 0.011 15.2 0.0 1.1 1 0 0 1 1 1 1 Copine DUF2101 PF09874.9 EGC32485.1 - 0.064 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) PD40 PF07676.12 EGC32485.1 - 0.069 13.1 0.2 1.5 8.8 0.2 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat vWA-TerF-like PF10138.9 EGC32486.1 - 4.4e-09 36.7 0.0 5.6e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC32486.1 - 1.5e-06 28.6 0.0 2.1e-06 28.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.6 EGC32486.1 - 2.9e-06 27.3 0.0 5e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC32486.1 - 1.6e-05 25.5 0.0 2.8e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain PD40 PF07676.12 EGC32486.1 - 0.11 12.5 0.1 4.2 7.4 0.1 2.6 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat FNIP PF05725.12 EGC32488.1 - 5e-15 55.4 12.1 7.4e-08 32.4 2.8 4.9 2 2 3 5 5 5 5 FNIP Repeat CHCH PF06747.13 EGC32489.1 - 3e-06 27.2 12.4 1.5e-05 25.0 6.7 1.7 1 1 1 2 2 2 2 CHCH domain NDUF_B7 PF05676.13 EGC32489.1 - 0.0017 18.0 1.8 0.0023 17.6 1.8 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Pet191_N PF10203.9 EGC32489.1 - 0.025 14.9 4.2 0.038 14.3 4.2 1.2 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 CX9C PF16860.5 EGC32489.1 - 0.072 13.1 5.2 0.15 12.1 5.2 1.6 1 1 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, YqzE PF14038.6 EGC32490.1 - 3.7 7.6 5.4 5.3 7.1 2.1 2.5 1 1 1 2 2 2 0 YqzE-like protein Macoilin PF09726.9 EGC32493.1 - 0.00056 18.6 33.6 0.00068 18.3 33.6 1.0 1 0 0 1 1 1 1 Macoilin family SAP PF02037.27 EGC32493.1 - 0.034 13.9 0.2 0.11 12.2 0.2 2.0 1 0 0 1 1 1 0 SAP domain DUF1664 PF07889.12 EGC32493.1 - 0.048 13.7 18.2 0.032 14.3 3.2 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) NBD_C PF17042.5 EGC32493.1 - 0.13 12.8 0.4 0.2 12.1 0.4 1.4 1 0 0 1 1 1 0 Nucleotide-binding C-terminal domain FAM76 PF16046.5 EGC32493.1 - 7.3 5.9 32.8 1.6 8.0 29.0 1.7 1 1 1 2 2 2 0 FAM76 protein Vta1 PF04652.16 EGC32494.1 - 0.035 14.1 0.5 0.067 13.2 0.5 1.6 1 1 0 1 1 1 0 Vta1 like RNA_polI_A14 PF08203.11 EGC32494.1 - 0.63 10.8 3.5 1.2 9.9 3.5 1.6 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 Fusion_gly PF00523.18 EGC32495.1 - 0.039 12.2 0.1 0.039 12.2 0.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 LSM PF01423.22 EGC32498.1 - 2.9e-18 65.3 0.0 3.4e-18 65.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain DUF150_C PF17384.2 EGC32498.1 - 0.0008 19.5 0.1 0.0012 18.9 0.1 1.3 1 0 0 1 1 1 1 RimP C-terminal SH3 domain SM-ATX PF14438.6 EGC32498.1 - 0.04 14.1 0.0 0.051 13.7 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain EXS PF03124.14 EGC32499.1 - 1.2e-70 238.4 34.9 1.7e-70 238.0 34.9 1.2 1 0 0 1 1 1 1 EXS family SPX PF03105.19 EGC32499.1 - 1e-20 75.0 44.4 1.9e-12 47.8 11.2 3.7 2 1 2 4 4 4 3 SPX domain DUF2189 PF09955.9 EGC32500.1 - 0.29 11.4 6.7 2.5 8.3 1.0 3.3 3 2 0 3 3 3 0 Predicted integral membrane protein (DUF2189) DUF5523 PF17661.1 EGC32500.1 - 0.53 9.9 7.8 0.8 9.3 7.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) HCO3_cotransp PF00955.21 EGC32500.1 - 2.3 6.9 12.8 0.12 11.1 6.6 1.8 2 0 0 2 2 2 0 HCO3- transporter family Sterol_MT_C PF08498.10 EGC32501.1 - 4.5e-22 78.1 0.2 7.9e-22 77.4 0.2 1.4 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.12 EGC32501.1 - 1e-17 64.5 0.0 3e-17 63.0 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32501.1 - 9.5e-16 58.3 0.0 2e-15 57.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32501.1 - 7e-15 55.1 0.0 1.5e-14 54.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC32501.1 - 5.1e-13 49.2 0.0 9.2e-13 48.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGC32501.1 - 6.4e-11 42.1 0.0 8.2e-11 41.7 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.18 EGC32501.1 - 1.3e-08 34.5 0.0 1.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGC32501.1 - 9e-08 32.8 0.0 3.3e-07 30.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain PCMT PF01135.19 EGC32501.1 - 0.014 15.1 0.0 0.028 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 EGC32501.1 - 0.024 14.5 0.0 0.061 13.2 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_32 PF13679.6 EGC32501.1 - 0.047 13.7 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2407_C PF13373.6 EGC32502.1 - 0.7 10.1 11.5 2.5 8.3 11.5 2.0 1 1 0 1 1 1 0 DUF2407 C-terminal domain Orf78 PF06024.12 EGC32502.1 - 1.6 9.1 17.5 8.4 6.8 16.3 2.9 2 1 0 2 2 2 0 Orf78 (ac78) Dapper PF15268.6 EGC32502.1 - 3.2 6.5 14.0 4.7 5.9 14.0 1.1 1 0 0 1 1 1 0 Dapper ATP_bind_3 PF01171.20 EGC32504.1 - 6e-16 58.7 0.0 3.1e-15 56.4 0.0 2.2 2 0 0 2 2 2 1 PP-loop family zn-ribbon_14 PF16503.5 EGC32504.1 - 5.2e-14 51.4 6.8 5.2e-14 51.4 6.8 3.4 5 0 0 5 5 5 1 Zinc-ribbon TF_Zn_Ribbon PF08271.12 EGC32504.1 - 0.048 13.2 0.3 0.048 13.2 0.3 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding CTU2 PF10288.9 EGC32504.1 - 0.37 11.0 7.7 0.11 12.8 1.4 2.9 3 1 0 3 3 3 0 Cytoplasmic tRNA 2-thiolation protein 2 zf-TRAF PF02176.18 EGC32505.1 - 3e-13 50.2 19.5 1.6e-08 35.1 5.5 3.8 3 1 1 4 4 4 3 TRAF-type zinc finger zf-RING_6 PF14835.6 EGC32505.1 - 2.1 8.3 8.8 0.25 11.2 3.2 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-ACC PF17848.1 EGC32505.1 - 4.8 7.4 10.4 0.64 10.1 0.2 4.7 5 0 0 5 5 5 0 Acetyl-coA carboxylase zinc finger domain Ly49 PF08391.10 EGC32506.1 - 0.64 10.4 5.8 0.54 10.6 0.2 2.7 2 1 0 2 2 2 0 Ly49-like protein, N-terminal region VP4_haemagglut PF00426.18 EGC32508.1 - 0.044 14.0 1.4 0.056 13.6 1.4 1.2 1 0 0 1 1 1 0 Outer Capsid protein VP4 (Hemagglutinin) Concanavalin-like domain WD40 PF00400.32 EGC32509.1 - 4.2e-27 93.8 13.4 8.6e-09 35.9 0.2 6.1 5 0 0 5 5 5 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32509.1 - 1.7e-23 82.7 0.5 0.003 17.8 0.0 6.1 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC32509.1 - 1.6e-08 34.7 2.6 0.0034 17.3 1.2 3.3 1 1 3 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGC32509.1 - 4.9e-06 25.5 2.8 3e-05 22.9 1.9 2.5 1 1 1 2 2 2 1 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGC32509.1 - 0.0013 17.7 1.5 0.22 10.4 0.2 3.4 1 1 2 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein SR-25 PF10500.9 EGC32509.1 - 0.11 12.1 23.4 0.18 11.4 6.5 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein WD40_like PF17005.5 EGC32509.1 - 0.31 10.3 2.7 6.7 5.9 0.1 3.0 2 1 1 3 3 3 0 WD40-like domain IMUP PF15761.5 EGC32509.1 - 9.6 7.0 21.9 0.29 11.8 6.8 2.5 2 0 0 2 2 2 0 Immortalisation up-regulated protein CLU PF13236.6 EGC32510.1 - 2.6e-62 210.6 0.0 5.9e-62 209.4 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC32510.1 - 1.7e-06 28.2 0.1 8.9e-06 25.8 0.1 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 Dimer_Tnp_hAT PF05699.14 EGC32511.1 - 0.00084 19.1 0.1 0.0012 18.6 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Mhr1 PF12829.7 EGC32512.1 - 0.051 13.7 0.3 0.11 12.6 0.3 1.5 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination EGF_2 PF07974.13 EGC32513.1 - 2.7e-05 24.4 7.0 5.7e-05 23.4 7.0 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGC32513.1 - 0.0011 19.1 7.8 0.0019 18.3 7.8 1.4 1 0 0 1 1 1 1 Laminin EGF domain EGF_Tenascin PF18720.1 EGC32513.1 - 0.0027 17.7 4.3 0.0053 16.8 4.3 1.5 1 1 0 1 1 1 1 Tenascin EGF domain EGF_alliinase PF04863.13 EGC32513.1 - 0.089 13.2 5.5 0.18 12.2 5.5 1.5 1 1 0 1 1 1 0 Alliinase EGF-like domain MRP_L53 PF10780.9 EGC32513.1 - 0.11 12.7 0.1 0.25 11.6 0.1 1.6 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Pox_A21 PF05323.12 EGC32514.1 - 0.025 15.1 5.5 0.041 14.5 3.0 2.1 2 0 0 2 2 2 0 Poxvirus A21 Protein Mem_trans PF03547.18 EGC32514.1 - 0.068 11.6 1.1 0.089 11.2 1.1 1.3 1 0 0 1 1 1 0 Membrane transport protein EF1G PF00647.19 EGC32515.1 - 5.2e-43 145.4 0.1 1.1e-42 144.5 0.1 1.5 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.20 EGC32515.1 - 9e-16 58.0 0.0 9e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC32515.1 - 4.8e-09 36.3 2.1 9e-09 35.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC32515.1 - 4.8e-07 30.0 0.0 9.8e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC32515.1 - 7.5e-06 26.3 0.0 2.4e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC32515.1 - 6.1e-05 23.2 0.0 0.00018 21.7 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC32515.1 - 9e-05 22.4 0.0 0.00022 21.2 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_5 PF18485.1 EGC32515.1 - 0.005 17.2 0.0 0.012 15.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC32515.1 - 0.024 14.4 0.0 0.056 13.2 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 EGC32515.1 - 0.24 12.0 2.6 0.7 10.5 2.6 1.7 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain zf-U11-48K PF05253.12 EGC32516.1 - 0.026 14.4 0.1 0.059 13.3 0.1 1.7 1 0 0 1 1 1 0 U11-48K-like CHHC zinc finger zf-RING_UBOX PF13445.6 EGC32516.1 - 2.1 8.5 8.2 10 6.3 8.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger Dimer_Tnp_hAT PF05699.14 EGC32517.1 - 1.1e-08 34.7 0.2 1.6e-08 34.2 0.2 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF3112 PF11309.8 EGC32519.1 - 0.13 11.7 0.0 0.16 11.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Ank_2 PF12796.7 EGC32520.1 - 2.1e-29 102.0 13.3 4.3e-06 27.2 0.2 8.5 4 2 4 9 9 9 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC32520.1 - 1.5e-24 86.0 11.1 0.0006 20.3 0.0 10.6 10 1 0 11 11 11 5 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC32520.1 - 6e-17 61.5 18.6 0.17 12.3 0.1 12.6 7 4 9 16 16 16 6 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC32520.1 - 2.3e-13 49.0 12.5 0.21 12.2 0.1 13.2 14 1 3 17 17 17 2 Ankyrin repeat Ank PF00023.30 EGC32520.1 - 0.00029 21.1 5.8 6.3 7.4 0.2 7.1 7 1 0 7 7 7 2 Ankyrin repeat DUF5049 PF16468.5 EGC32520.1 - 0.0031 17.4 0.6 8.8 6.3 0.0 5.6 5 1 1 6 6 6 1 Domain of unknown function (DUF5049) RTTN_N PF14726.6 EGC32522.1 - 0.17 12.7 5.3 0.51 11.2 0.5 3.7 3 1 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning EF-hand_6 PF13405.6 EGC32524.1 - 3.3e-16 57.8 0.8 2.4e-06 27.0 0.0 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.6 EGC32524.1 - 8.8e-15 54.9 0.0 2.1e-06 28.1 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC32524.1 - 2.4e-14 51.7 2.0 9.6e-06 24.8 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.6 EGC32524.1 - 1.6e-09 36.8 1.5 0.00046 19.5 0.0 3.1 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGC32524.1 - 2.9e-09 36.6 0.7 2.9e-06 27.0 0.0 3.6 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.6 EGC32524.1 - 5e-06 26.7 0.0 0.13 12.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.13 EGC32524.1 - 0.019 15.0 0.0 2.2 8.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) UBA_6 PF18039.1 EGC32524.1 - 0.023 14.6 0.0 2.8 8.0 0.0 2.5 2 0 0 2 2 2 0 UBA-like domain DUF853 PF05872.12 EGC32524.1 - 0.035 12.7 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DUF937 PF06078.11 EGC32524.1 - 0.07 13.7 0.1 0.081 13.5 0.1 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) DUF2666 PF10869.8 EGC32524.1 - 0.071 13.3 0.0 2.2 8.5 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) Coatomer_WDAD PF04053.14 EGC32525.1 - 1.8e-160 534.9 0.1 1.8e-160 534.9 0.1 2.2 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.32 EGC32525.1 - 3.8e-43 144.6 7.7 1.1e-08 35.5 0.0 9.0 9 0 0 9 9 9 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32525.1 - 4.2e-10 39.8 0.7 2.4 8.5 0.0 6.4 5 2 2 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain TPR_8 PF13181.6 EGC32525.1 - 0.066 13.5 0.1 2 8.8 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF829 PF05705.14 EGC32527.1 - 3.9e-44 151.4 0.1 6.1e-44 150.7 0.1 1.3 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) WD40 PF00400.32 EGC32528.1 - 1.9e-14 53.8 2.2 1.2e-05 26.0 0.2 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat F-box-like PF12937.7 EGC32528.1 - 2.9e-10 39.9 0.0 6.8e-10 38.7 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC32528.1 - 8.2e-07 28.7 0.0 2.7e-06 27.1 0.0 2.0 1 0 0 1 1 1 1 F-box domain Cluap1 PF10234.9 EGC32528.1 - 0.052 12.9 0.1 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 Clusterin-associated protein-1 F-box_4 PF15966.5 EGC32528.1 - 0.071 13.0 2.2 0.11 12.4 0.0 2.5 3 0 0 3 3 3 0 F-box Pterin_bind PF00809.22 EGC32529.1 - 2.6e-70 236.9 0.0 6.2e-70 235.6 0.0 1.6 2 0 0 2 2 2 1 Pterin binding enzyme HPPK PF01288.20 EGC32529.1 - 1.4e-33 115.7 0.0 2.8e-33 114.7 0.0 1.5 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.18 EGC32529.1 - 9.1e-25 87.4 0.0 1.7e-24 86.5 0.0 1.5 1 0 0 1 1 1 1 Dihydroneopterin aldolase Tubulin-binding PF00418.19 EGC32529.1 - 0.031 14.3 0.1 0.13 12.3 0.0 2.1 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat Beta_helix PF13229.6 EGC32530.1 - 0.0036 17.2 13.4 0.0036 17.2 13.4 6.1 1 1 3 5 5 5 3 Right handed beta helix region VWA_3 PF13768.6 EGC32531.1 - 3.7e-11 43.2 0.0 5.3e-11 42.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC32531.1 - 5.2e-05 23.8 0.0 9.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGC32531.1 - 0.038 13.4 0.0 0.35 10.2 0.0 2.0 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein SdrD_B PF17210.3 EGC32531.1 - 0.062 13.5 0.7 3.6 7.9 0.0 3.1 2 1 0 3 3 3 0 SdrD B-like domain SGTA_dimer PF16546.5 EGC32531.1 - 0.071 12.9 0.1 14 5.5 0.0 2.5 2 0 0 2 2 2 0 Homodimerisation domain of SGTA Peptidase_S49_N PF08496.10 EGC32531.1 - 0.13 12.3 0.3 7.7 6.6 0.2 2.2 1 1 1 2 2 2 0 Peptidase family S49 N-terminal Filamin PF00630.19 EGC32531.1 - 0.16 12.8 2.1 2.4 9.0 0.0 2.6 1 1 0 2 2 2 0 Filamin/ABP280 repeat DUF3516 PF12029.8 EGC32532.1 - 0.056 12.5 0.0 0.085 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF4131 PF13567.6 EGC32532.1 - 0.11 12.1 0.3 0.13 11.9 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) VWA_3 PF13768.6 EGC32533.1 - 6.2e-08 32.7 0.0 1e-07 32.0 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain ADP_PFK_GK PF04587.15 EGC32533.1 - 0.069 11.7 0.1 0.13 10.8 0.1 1.4 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region VWA_2 PF13519.6 EGC32533.1 - 0.17 12.6 0.0 0.35 11.5 0.0 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain Reticulon PF02453.17 EGC32533.1 - 0.19 11.7 14.6 0.15 12.1 12.8 1.7 1 1 1 2 2 2 0 Reticulon VWA_3 PF13768.6 EGC32534.1 - 1.7e-09 37.8 0.0 2.7e-09 37.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Reticulon PF02453.17 EGC32534.1 - 0.003 17.5 10.1 0.0054 16.7 10.1 1.4 1 0 0 1 1 1 1 Reticulon PMD PF10536.9 EGC32534.1 - 0.027 13.6 0.1 0.06 12.4 0.1 1.5 1 1 0 1 1 1 0 Plant mobile domain DUF3488 PF11992.8 EGC32534.1 - 3.9 6.3 5.3 1.5 7.7 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) Ribul_P_3_epim PF00834.19 EGC32535.1 - 2.7e-72 242.4 0.2 3.1e-72 242.1 0.2 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family NanE PF04131.14 EGC32535.1 - 0.0051 16.0 0.0 0.0064 15.7 0.0 1.1 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase M20_dimer PF07687.14 EGC32535.1 - 0.02 14.8 0.0 0.033 14.1 0.0 1.5 1 1 0 1 1 1 0 Peptidase dimerisation domain QRPTase_C PF01729.19 EGC32535.1 - 0.035 13.9 0.0 0.11 12.3 0.0 1.6 1 1 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain PEP_hydrolase PF09370.10 EGC32535.1 - 0.04 13.1 0.1 2.3 7.4 0.1 2.7 2 1 1 3 3 3 0 Phosphoenolpyruvate hydrolase-like His_biosynth PF00977.21 EGC32535.1 - 0.048 13.1 0.0 1 8.8 0.0 2.2 2 0 0 2 2 2 0 Histidine biosynthesis protein FMN_dh PF01070.18 EGC32535.1 - 0.084 11.9 0.0 0.39 9.7 0.0 1.9 2 0 0 2 2 2 0 FMN-dependent dehydrogenase PcrB PF01884.17 EGC32535.1 - 0.093 12.2 0.1 2.9 7.3 0.0 2.1 2 0 0 2 2 2 0 PcrB family MMM1 PF10296.9 EGC32536.1 - 2.7e-06 26.7 0.0 3.3e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF3800 PF12686.7 EGC32537.1 - 3.5 8.3 7.9 4.3 8.0 7.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3800) DUF4065 PF13274.6 EGC32537.1 - 7.2 7.5 10.3 1.3 9.9 6.9 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) Cofilin_ADF PF00241.20 EGC32538.1 - 2e-36 124.5 0.6 2.2e-36 124.3 0.6 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.22 EGC32539.1 - 3.2e-39 134.1 0.1 3.2e-39 134.1 0.1 1.7 2 0 0 2 2 2 1 Ras family Roc PF08477.13 EGC32539.1 - 1.7e-20 73.5 0.6 2.4e-19 69.7 0.0 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32539.1 - 2e-05 24.1 0.0 3.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC32539.1 - 0.0014 18.7 0.6 0.0055 16.8 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGC32539.1 - 0.12 12.1 0.1 0.12 12.1 0.1 2.4 2 1 0 2 2 2 0 AAA domain ArAE_2_N PF10337.9 EGC32539.1 - 0.41 9.6 3.5 0.55 9.2 3.5 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal Ctr PF04145.15 EGC32539.1 - 0.79 10.3 2.5 2 9.0 2.5 1.8 1 0 0 1 1 1 0 Ctr copper transporter family EMC3_TMCO1 PF01956.16 EGC32539.1 - 3.8 7.2 4.6 6.5 6.4 4.6 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like tRNA-synt_1 PF00133.22 EGC32540.1 - 2.2e-47 161.7 0.0 1.9e-22 79.3 0.0 3.3 3 1 0 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.11 EGC32540.1 - 1.3e-19 70.3 0.3 5.5e-09 35.3 0.0 2.7 3 0 0 3 3 3 2 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGC32540.1 - 8.7e-12 45.3 0.6 3.3e-11 43.4 0.1 2.2 1 1 1 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGC32540.1 - 5.3e-08 32.6 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGC32540.1 - 0.068 12.1 0.0 0.16 10.9 0.0 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (K) EGF_2 PF07974.13 EGC32542.1 - 8.1e-08 32.5 35.9 0.00046 20.5 14.1 2.9 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.10 EGC32542.1 - 0.00092 18.6 5.4 0.0021 17.4 5.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_Tenascin PF18720.1 EGC32542.1 - 0.0017 18.4 23.7 0.021 14.9 7.2 2.8 2 0 0 2 2 2 2 Tenascin EGF domain CD99L2 PF12301.8 EGC32542.1 - 0.18 12.1 0.1 0.18 12.1 0.1 1.7 2 0 0 2 2 2 0 CD99 antigen like protein 2 EGF PF00008.27 EGC32542.1 - 0.53 10.6 30.2 2.3 8.6 12.2 2.8 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 EGC32542.1 - 4.1 7.6 32.2 1.8 8.8 9.5 3.4 3 0 0 3 3 3 0 Laminin EGF domain TIG PF01833.24 EGC32543.1 - 5.8e-05 23.1 15.1 0.0019 18.3 0.2 4.8 5 1 0 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC32543.1 - 0.00033 20.9 29.7 0.00089 19.6 10.1 3.0 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC32543.1 - 0.66 10.2 23.8 0.28 11.4 7.8 3.2 3 0 0 3 3 3 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC32543.1 - 1.2 9.2 14.0 2.6 8.2 4.7 2.7 2 0 0 2 2 2 0 Tenascin EGF domain zf-C3HC4_2 PF13923.6 EGC32544.1 - 3.8e-08 33.0 12.1 8.2e-08 32.0 12.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32544.1 - 7.4e-08 32.6 12.5 7.4e-08 32.6 12.5 1.8 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC32544.1 - 2e-07 30.7 10.1 2e-07 30.7 10.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC32544.1 - 1.2e-05 25.0 14.5 1.2e-05 25.0 14.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC32544.1 - 0.00049 20.1 8.1 0.0014 18.6 8.1 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGC32544.1 - 0.00074 19.2 5.7 0.0021 17.8 5.7 1.8 1 0 0 1 1 1 1 RING-like zinc finger DUF4834 PF16118.5 EGC32544.1 - 0.0028 18.6 2.0 0.0028 18.6 2.0 4.5 2 1 0 3 3 2 1 Domain of unknown function (DUF4834) zf-RING_5 PF14634.6 EGC32544.1 - 0.0037 17.2 12.3 0.0037 17.2 12.3 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGC32544.1 - 0.0051 16.7 4.3 0.011 15.6 4.3 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGC32544.1 - 0.016 15.0 13.2 0.041 13.7 13.2 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC32544.1 - 0.32 11.3 12.9 0.062 13.6 8.3 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC32544.1 - 1.8 8.8 18.7 0.097 12.8 13.1 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING Mitofilin PF09731.9 EGC32548.1 - 0.22 10.3 6.2 0.24 10.2 6.2 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FNIP PF05725.12 EGC32549.1 - 2.9e-207 670.7 96.9 1.3e-15 57.3 0.7 14.6 4 2 16 21 21 21 21 FNIP Repeat Xol-1_GHMP-like PF09109.10 EGC32549.1 - 0.02 14.8 1.1 33 4.3 0.0 5.0 6 0 0 6 6 6 0 Switch protein XOL-1, GHMP-like Chromo PF00385.24 EGC32550.1 - 3e-07 30.2 0.7 4.6e-07 29.6 0.7 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Carn_acyltransf PF00755.20 EGC32550.1 - 0.099 11.2 0.1 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 Choline/Carnitine o-acyltransferase DSPc PF00782.20 EGC32551.1 - 8.3e-32 109.8 0.7 9.3e-32 109.6 0.7 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC32551.1 - 4.4e-06 26.5 0.0 6.1e-06 26.0 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC32551.1 - 0.017 15.2 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Cupin_8 PF13621.6 EGC32552.1 - 2.6e-20 73.2 6.7 5.5e-20 72.1 0.4 2.9 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.22 EGC32552.1 - 3e-10 40.5 14.2 1e-06 29.1 3.0 4.1 3 1 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.12 EGC32552.1 - 3.6e-07 30.0 0.1 1.1e-06 28.3 0.0 1.9 3 0 0 3 3 3 1 Cupin superfamily protein Gti1_Pac2 PF09729.9 EGC32552.1 - 0.014 15.5 4.8 0.014 15.5 4.8 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF3947 PF13135.6 EGC32552.1 - 0.075 13.2 0.2 0.17 12.1 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) F-box PF00646.33 EGC32552.1 - 0.084 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 F-box domain Cupin_1 PF00190.22 EGC32552.1 - 0.091 12.4 0.0 0.18 11.4 0.0 1.5 1 0 0 1 1 1 0 Cupin Cupin_2 PF07883.11 EGC32552.1 - 0.11 12.2 0.0 0.41 10.4 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DUF724 PF05266.14 EGC32552.1 - 0.79 9.5 16.6 0.023 14.5 7.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATP11 PF06644.11 EGC32552.1 - 1.1 9.0 15.4 0.62 9.8 6.5 2.3 2 0 0 2 2 2 0 ATP11 protein MDM10 PF12519.8 EGC32552.1 - 1.2 7.9 13.6 1.8 7.3 13.6 1.2 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 EMC3_TMCO1 PF01956.16 EGC32552.1 - 3.9 7.2 17.3 1.9 8.2 7.7 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like U1snRNP70_N PF12220.8 EGC32552.1 - 4 8.2 16.9 8.8 7.0 3.5 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4407 PF14362.6 EGC32552.1 - 7.6 5.8 8.2 0.97 8.7 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PcfK PF14058.6 EGC32552.1 - 9.2 6.6 26.2 0.4 11.0 13.7 2.4 2 0 0 2 2 2 0 PcfK-like protein BING4CT PF08149.11 EGC32553.1 - 2.7e-33 113.6 3.5 3.4e-32 110.1 0.0 3.5 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.32 EGC32553.1 - 4e-06 27.5 0.2 0.00083 20.1 0.0 4.2 5 0 0 5 5 5 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32553.1 - 0.0027 18.0 0.0 5.2 7.4 0.0 4.0 3 2 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain SPA PF08616.10 EGC32555.1 - 5.6e-13 48.8 0.0 1.4e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.9 EGC32555.1 - 8.5e-12 44.4 0.3 3e-11 42.6 0.3 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.21 EGC32555.1 - 2.1e-05 24.5 0.7 0.0007 19.6 0.1 2.7 2 1 0 2 2 2 1 DENN (AEX-3) domain Afi1 PF07792.12 EGC32555.1 - 0.0097 16.4 4.4 0.013 16.0 0.0 2.5 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF737 PF05300.11 EGC32555.1 - 4.3 7.6 10.8 8.5 6.7 10.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF737) FtsJ PF01728.19 EGC32556.1 - 2.3e-66 223.3 0.0 2.9e-66 222.9 0.0 1.1 1 0 0 1 1 1 1 FtsJ-like methyltransferase Ubie_methyltran PF01209.18 EGC32556.1 - 0.0044 16.4 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltr_RsmB-F PF01189.17 EGC32556.1 - 0.055 13.1 0.0 0.2 11.3 0.0 1.8 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Methyltransf_23 PF13489.6 EGC32556.1 - 0.1 12.4 0.0 0.3 10.9 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Nop25 PF09805.9 EGC32557.1 - 9.3e-08 32.6 55.4 9.3e-08 32.6 55.4 3.2 1 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) BUD22 PF09073.10 EGC32557.1 - 7.2 5.8 50.6 0.032 13.6 35.6 2.0 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.25 EGC32558.1 - 4.8e-72 242.5 0.3 1.1e-71 241.3 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32558.1 - 1.3e-41 142.6 0.0 2.2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC32558.1 - 0.02 14.2 0.0 0.036 13.4 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGC32558.1 - 0.055 13.4 0.0 0.18 11.7 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family BTB PF00651.31 EGC32559.1 - 1.6e-10 41.2 2.1 2e-10 40.9 0.5 2.0 2 0 0 2 2 2 1 BTB/POZ domain SAM_2 PF07647.17 EGC32559.1 - 4.9e-05 23.3 0.0 0.00013 22.1 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC32559.1 - 0.0014 19.1 0.0 0.0029 18.0 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PheRS_DBD2 PF18554.1 EGC32559.1 - 0.0048 16.9 0.8 0.013 15.4 0.8 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 2 Pkinase PF00069.25 EGC32560.1 - 1e-74 251.3 0.0 1.5e-74 250.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32560.1 - 1.7e-36 125.8 0.0 2.5e-36 125.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGC32560.1 - 3.2e-05 24.5 0.1 3.2e-05 24.5 0.1 2.1 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.6 EGC32560.1 - 0.00053 19.4 0.0 0.0054 16.1 0.0 2.2 2 0 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGC32560.1 - 0.00075 19.2 0.2 0.56 9.8 0.1 2.4 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGC32560.1 - 0.013 14.5 1.8 0.021 13.8 1.7 1.5 1 1 0 1 1 1 0 Haspin like kinase domain APH PF01636.23 EGC32560.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC32560.1 - 0.025 13.4 6.0 0.23 10.2 6.0 2.1 1 1 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGC32560.1 - 0.077 12.3 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PAP1 PF08601.10 EGC32560.1 - 1.3 8.7 21.5 1.8 8.2 21.5 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 Dicty_REP PF05086.12 EGC32560.1 - 5.2 4.9 18.4 6.7 4.6 18.4 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein MAP65_ASE1 PF03999.12 EGC32560.1 - 5.3 5.6 16.6 7.4 5.1 16.6 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF4551 PF15087.6 EGC32560.1 - 5.7 5.7 6.6 6.8 5.4 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Hamartin PF04388.12 EGC32560.1 - 5.9 5.4 11.7 7.3 5.1 11.7 1.1 1 0 0 1 1 1 0 Hamartin protein MFS_1 PF07690.16 EGC32562.1 - 1.7e-19 70.0 67.7 1.7e-15 56.8 37.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGC32562.1 - 1.5e-09 37.0 25.5 7.2e-09 34.7 25.5 1.9 1 1 0 1 1 1 1 MFS/sugar transport protein BT1 PF03092.16 EGC32562.1 - 0.00043 18.6 12.0 0.031 12.5 2.5 2.3 2 0 0 2 2 2 2 BT1 family Sugar_tr PF00083.24 EGC32562.1 - 0.019 13.8 26.4 0.071 12.0 14.2 2.4 2 1 0 2 2 2 0 Sugar (and other) transporter AMP-binding PF00501.28 EGC32563.1 - 4.8e-67 226.4 0.0 2.1e-56 191.4 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.12 EGC32563.1 - 2.6e-32 112.0 0.0 5.8e-32 110.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Myb_DNA-binding PF00249.31 EGC32563.1 - 3.5e-15 55.9 5.8 5.6e-08 32.8 1.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC32563.1 - 3.6e-10 40.0 8.0 2.1e-07 31.1 0.6 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain 3Beta_HSD PF01073.19 EGC32563.1 - 1.8e-06 27.2 0.1 3.6e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC32563.1 - 5.6e-05 22.7 0.0 0.00016 21.2 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC32563.1 - 0.00078 18.9 0.1 0.00078 18.9 0.1 2.3 3 0 0 3 3 3 1 GDP-mannose 4,6 dehydratase AMP-binding_C PF13193.6 EGC32563.1 - 0.012 16.6 0.0 0.029 15.3 0.0 1.7 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain zf-TRAF PF02176.18 EGC32564.1 - 4.7e-13 49.6 40.0 2.9e-09 37.5 8.4 4.6 1 1 3 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC32564.1 - 0.00015 21.6 4.9 0.00015 21.6 4.9 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC32564.1 - 0.00025 21.4 31.5 0.00061 20.2 11.7 3.5 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC32564.1 - 0.03 14.6 7.2 0.03 14.6 7.2 4.4 2 1 1 3 3 3 0 Ring finger domain PARP PF00644.20 EGC32566.1 - 0.00015 21.4 0.1 0.00024 20.7 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Exotox-A_cataly PF09009.10 EGC32566.1 - 0.011 15.5 0.0 0.033 13.9 0.0 1.8 1 1 1 2 2 2 0 Exotoxin A catalytic DUF1456 PF07308.13 EGC32566.1 - 0.11 12.8 0.2 0.27 11.6 0.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1456) NDUF_B7 PF05676.13 EGC32569.1 - 1.1e-26 92.4 5.7 1.5e-26 91.9 5.7 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.10 EGC32569.1 - 0.00013 21.9 2.6 0.00018 21.4 2.6 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like FNIP PF05725.12 EGC32570.1 - 8e-106 346.0 70.5 1.4e-15 57.2 1.4 13.2 8 3 7 15 15 15 14 FNIP Repeat ACDC PF14733.6 EGC32570.1 - 1.5 9.2 3.8 91 3.5 0.0 4.4 6 0 0 6 6 6 0 AP2-coincident C-terminal ubiquitin PF00240.23 EGC32571.1 - 9.3e-103 336.1 11.2 1.5e-33 114.3 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGC32571.1 - 1.1e-47 159.7 11.5 3.4e-15 55.6 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC32571.1 - 9.3e-18 64.5 4.2 0.00042 20.7 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC32571.1 - 1.9e-11 44.2 4.2 0.024 15.0 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC32571.1 - 2.7e-11 43.2 1.7 0.041 13.8 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC32571.1 - 1.4e-10 41.2 0.8 0.12 12.5 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC32571.1 - 4.1e-09 36.9 0.1 0.36 11.4 0.0 3.2 1 1 1 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGC32571.1 - 4.1e-06 26.7 14.2 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGC32571.1 - 7e-06 26.0 0.0 2.8 7.7 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 EGC32571.1 - 0.00015 22.0 0.3 20 5.6 0.0 4.2 3 3 3 6 6 6 0 Protein of unknown function (DUF2870) Methyltrans_RNA PF04452.14 EGC32571.1 - 0.00026 20.4 0.2 0.72 9.1 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase ACT_5 PF13710.6 EGC32571.1 - 0.00082 19.2 0.8 17 5.4 0.0 3.3 3 0 0 3 3 3 0 ACT domain DUF3861 PF12977.7 EGC32571.1 - 0.0015 18.6 0.5 24 5.2 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) N1221 PF07923.13 EGC32571.1 - 0.0032 16.7 0.2 18 4.4 0.0 3.0 3 0 0 3 3 3 0 N1221-like protein UDP-g_GGTase PF06427.11 EGC32571.1 - 0.0047 17.0 2.4 4.3 7.5 0.0 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 EGC32571.1 - 0.0061 17.3 0.0 60 4.5 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain DUF969 PF06149.12 EGC32571.1 - 0.0069 15.8 0.0 14 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) Big_3_3 PF13750.6 EGC32571.1 - 0.0078 15.9 0.0 31 4.2 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) DUF3435 PF11917.8 EGC32571.1 - 0.011 14.6 0.1 21 3.9 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) Corona_NS2A PF05213.12 EGC32571.1 - 0.014 14.8 0.0 26 4.0 0.0 3.0 3 0 0 3 3 3 0 Coronavirus NS2A protein ACT_4 PF13291.6 EGC32571.1 - 0.015 15.9 0.1 78 4.0 0.0 3.3 3 0 0 3 3 3 0 ACT domain Imm12 PF15560.6 EGC32571.1 - 0.025 14.6 0.5 51 3.8 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 12 ORF11CD3 PF10549.9 EGC32571.1 - 0.062 13.4 0.0 62 3.8 0.0 3.7 3 0 0 3 3 3 0 ORF11CD3 domain PTS-HPr PF00381.19 EGC32571.1 - 0.079 13.2 0.4 1.1e+02 3.2 0.0 3.4 3 0 0 3 3 3 0 PTS HPr component phosphorylation site ProRS-C_2 PF09181.10 EGC32571.1 - 0.13 12.4 2.3 77 3.5 0.1 3.2 3 0 0 3 3 3 0 Prolyl-tRNA synthetase, C-terminal YcgR_2 PF12945.7 EGC32571.1 - 0.25 11.5 2.0 1.1e+02 3.1 0.1 3.2 3 0 0 3 3 3 0 Flagellar protein YcgR DMA PF03474.14 EGC32571.1 - 0.42 10.2 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif FlgD_ig PF13860.6 EGC32571.1 - 0.74 9.7 4.1 92 3.0 0.1 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain VHS PF00790.19 EGC32572.1 - 1.5e-22 80.0 1.0 1.5e-22 80.0 1.0 2.1 2 1 0 2 2 2 1 VHS domain GAT PF03127.14 EGC32572.1 - 5.3e-18 65.1 2.6 5.3e-18 65.1 2.6 2.1 2 0 0 2 2 2 1 GAT domain MIOX PF05153.15 EGC32573.1 - 7.4e-113 376.2 5.5 8.2e-113 376.1 5.5 1.0 1 0 0 1 1 1 1 Myo-inositol oxygenase Sdh5 PF03937.16 EGC32573.1 - 0.027 14.4 0.1 0.08 12.9 0.1 1.8 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase HD PF01966.22 EGC32573.1 - 0.11 12.7 0.0 0.25 11.6 0.0 1.6 1 0 0 1 1 1 0 HD domain Ribosomal_L30 PF00327.20 EGC32574.1 - 2.7e-15 56.0 0.1 4.3e-15 55.3 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S17e PF00833.18 EGC32575.1 - 6.2e-57 190.8 2.1 7.3e-57 190.6 2.1 1.0 1 0 0 1 1 1 1 Ribosomal S17 TPR_2 PF07719.17 EGC32576.1 - 2e-05 24.3 10.5 0.49 10.6 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32576.1 - 0.00034 20.3 13.6 0.7 9.8 0.0 6.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32576.1 - 0.00097 19.4 2.0 1.2 9.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32576.1 - 0.25 11.9 10.0 38 4.9 0.0 5.6 6 2 0 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32576.1 - 4.6 7.0 8.1 11 5.7 0.0 4.3 5 0 0 5 5 5 0 TPR repeat TPR_8 PF13181.6 EGC32576.1 - 6.8 7.2 18.3 17 6.0 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat FNIP PF05725.12 EGC32577.1 - 3.1e-14 52.8 60.0 2.1e-05 24.6 0.5 10.8 4 3 2 10 10 10 8 FNIP Repeat SAP30_Sin3_bdg PF13867.6 EGC32579.1 - 2.1e-17 63.2 0.5 3.2e-17 62.6 0.5 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CENP-X PF09415.10 EGC32580.1 - 2.6e-11 43.7 0.1 3.2e-11 43.4 0.1 1.1 1 0 0 1 1 1 1 CENP-S associating Centromere protein X NmrA PF05368.13 EGC32581.1 - 2e-55 187.9 0.0 2.5e-55 187.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC32581.1 - 2e-12 47.4 0.0 3.1e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding PALP PF00291.25 EGC32581.1 - 0.024 14.0 0.0 0.043 13.2 0.0 1.4 1 1 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF1084 PF06454.11 EGC32582.1 - 1.3e-09 37.9 20.0 2.9e-09 36.7 20.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF4073 PF13285.6 EGC32582.1 - 0.034 13.8 0.0 0.073 12.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Vma12 PF11712.8 EGC32582.1 - 0.21 11.7 0.7 1.1 9.4 0.9 2.1 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF4818 PF16089.5 EGC32584.1 - 1.6 9.2 13.4 0.35 11.4 0.3 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4818) EcsB PF05975.12 EGC32584.1 - 2 7.2 19.6 0.044 12.6 9.5 2.5 2 1 1 3 3 3 0 Bacterial ABC transporter protein EcsB Peptidase_A8 PF01252.18 EGC32584.1 - 3.2 8.0 13.0 1.3 9.3 2.3 3.2 1 1 2 3 3 3 0 Signal peptidase (SPase) II DUF2919 PF11143.8 EGC32584.1 - 5.5 7.3 14.1 1.3 9.4 8.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2919) Plant_vir_prot PF01307.17 EGC32584.1 - 6.8 7.0 29.2 1.1 9.5 0.7 5.1 1 1 3 5 5 5 0 Plant viral movement protein FlxA PF14282.6 EGC32585.1 - 0.033 14.2 2.4 0.046 13.7 2.4 1.2 1 0 0 1 1 1 0 FlxA-like protein DUF792 PF05632.11 EGC32585.1 - 0.045 13.6 0.3 0.062 13.2 0.3 1.3 1 1 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) Toxin_trans PF07952.12 EGC32585.1 - 0.056 12.5 1.2 0.062 12.4 1.2 1.1 1 0 0 1 1 1 0 Clostridium neurotoxin, Translocation domain UN_NPL4 PF11543.8 EGC32585.1 - 0.064 13.8 3.1 4.9 7.7 0.1 2.2 1 1 1 2 2 2 0 Nuclear pore localisation protein NPL4 HALZ PF02183.18 EGC32585.1 - 0.071 13.3 1.0 0.071 13.3 1.0 2.3 2 1 0 2 2 2 0 Homeobox associated leucine zipper DUF5595 PF18077.1 EGC32585.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF5595) DivIC PF04977.15 EGC32585.1 - 0.42 10.4 4.3 0.16 11.7 0.9 2.0 2 1 0 2 2 2 0 Septum formation initiator bZIP_1 PF00170.21 EGC32585.1 - 1.7 8.8 12.1 4.2 7.5 1.5 2.5 2 1 1 3 3 3 0 bZIP transcription factor YabA PF06156.13 EGC32585.1 - 5.2 7.8 8.3 52 4.6 8.3 2.1 1 1 0 1 1 1 0 Initiation control protein YabA ZapB PF06005.12 EGC32585.1 - 6.5 7.3 12.3 8.7e+02 0.5 12.4 2.8 1 1 0 1 1 1 0 Cell division protein ZapB VRP1 PF03538.14 EGC32586.1 - 0.0048 16.4 0.4 0.0063 16.0 0.4 1.2 1 0 0 1 1 1 1 Salmonella virulence plasmid 28.1kDa A protein RINT1_TIP1 PF04437.13 EGC32587.1 - 1.9e-63 215.1 54.5 5.9e-53 180.5 19.7 3.9 3 1 0 3 3 3 2 RINT-1 / TIP-1 family Zip PF02535.22 EGC32587.1 - 2.3 7.3 12.8 2 7.6 2.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Tim54 PF11711.8 EGC32587.1 - 5.4 5.7 26.1 0.059 12.2 8.1 2.7 3 0 0 3 3 3 0 Inner membrane protein import complex subunit Tim54 Acyl-CoA_dh_1 PF00441.24 EGC32589.1 - 3.8e-24 85.6 0.0 1e-23 84.2 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain AidB_N PF18158.1 EGC32589.1 - 2.9e-23 82.5 0.0 4.1e-23 82.0 0.0 1.2 1 0 0 1 1 1 1 Adaptive response protein AidB N-terminal domain Acyl-CoA_dh_M PF02770.19 EGC32589.1 - 1.4e-07 31.6 0.0 2.5e-07 30.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC32589.1 - 2.5e-06 27.8 0.0 5e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_C PF12806.7 EGC32589.1 - 0.045 13.9 0.0 0.075 13.2 0.0 1.3 1 0 0 1 1 1 0 Acetyl-CoA dehydrogenase C-terminal like Thioredoxin_7 PF13899.6 EGC32590.1 - 2.4e-13 50.1 0.0 4.9e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like UBX PF00789.20 EGC32590.1 - 8.7e-12 45.1 0.2 3.9e-11 43.0 0.0 2.2 3 0 0 3 3 3 1 UBX domain UBA_4 PF14555.6 EGC32590.1 - 1.3e-11 44.1 0.7 3.5e-11 42.7 0.7 1.7 1 0 0 1 1 1 1 UBA-like domain Thioredoxin_2 PF13098.6 EGC32590.1 - 7.8e-06 26.3 0.0 2.1e-05 24.9 0.0 1.8 1 0 0 1 1 1 1 Thioredoxin-like domain RNA_pol_3_Rpc31 PF11705.8 EGC32590.1 - 0.0085 16.4 16.9 0.022 15.0 16.9 1.7 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 TAP_C PF03943.13 EGC32590.1 - 0.011 15.4 0.1 0.028 14.0 0.1 1.7 1 0 0 1 1 1 0 TAP C-terminal domain Arrestin_C PF02752.22 EGC32590.1 - 0.013 15.9 1.2 0.14 12.7 0.0 2.3 2 0 0 2 2 2 0 Arrestin (or S-antigen), C-terminal domain Nop14 PF04147.12 EGC32590.1 - 0.14 10.3 17.8 0.22 9.7 17.8 1.2 1 0 0 1 1 1 0 Nop14-like family TT_ORF2 PF02957.15 EGC32590.1 - 0.52 11.2 8.1 1.1 10.2 8.1 1.5 1 0 0 1 1 1 0 TT viral ORF2 FAM60A PF15396.6 EGC32590.1 - 2 8.4 5.5 5 7.1 5.5 1.6 1 0 0 1 1 1 0 Protein Family FAM60A DNA_pol_phi PF04931.13 EGC32590.1 - 2.4 6.2 19.8 4.3 5.3 19.8 1.3 1 0 0 1 1 1 0 DNA polymerase phi CSRNP_N PF16019.5 EGC32590.1 - 3 7.7 6.8 7.3 6.4 6.8 1.7 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Astro_capsid_p PF12226.8 EGC32590.1 - 3 6.9 11.6 6.3 5.8 11.6 1.5 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Presenilin PF01080.17 EGC32590.1 - 3 6.5 5.1 4.3 6.0 5.1 1.3 1 0 0 1 1 1 0 Presenilin NOA36 PF06524.12 EGC32591.1 - 0.00076 18.9 5.3 0.00087 18.7 5.3 1.0 1 0 0 1 1 1 1 NOA36 protein DUF2126 PF09899.9 EGC32591.1 - 0.039 12.0 0.5 0.043 11.9 0.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Zip PF02535.22 EGC32591.1 - 0.2 10.9 3.0 0.2 10.8 3.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 EGC32591.1 - 0.3 10.8 1.1 0.29 10.9 1.1 1.1 1 0 0 1 1 1 0 Connexin Phage_Gp23 PF10669.9 EGC32591.1 - 0.49 10.7 7.1 0.61 10.4 7.1 1.1 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) MAP17 PF15807.5 EGC32591.1 - 2.6 8.3 9.2 3.2 8.0 9.2 1.1 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Presenilin PF01080.17 EGC32591.1 - 4.7 5.9 7.4 5.1 5.7 7.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 EGC32591.1 - 5.9 6.2 6.9 6.4 6.1 6.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Cofilin_ADF PF00241.20 EGC32593.1 - 7.7e-12 45.1 1.0 1.4e-11 44.2 1.0 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Pectate_lyase_3 PF12708.7 EGC32594.1 - 0.0089 15.9 0.1 0.011 15.6 0.1 1.2 1 0 0 1 1 1 1 Pectate lyase superfamily protein MCM2_N PF12619.8 EGC32594.1 - 0.072 13.4 0.1 0.072 13.4 0.1 1.5 2 0 0 2 2 2 0 Mini-chromosome maintenance protein 2 Strep_SA_rep PF06696.11 EGC32595.1 - 4.1 7.5 6.3 2.8 8.1 0.7 2.8 3 0 0 3 3 3 0 Streptococcal surface antigen repeat NUC129 PF08157.11 EGC32596.1 - 0.12 12.8 0.2 0.27 11.6 0.2 1.6 1 0 0 1 1 1 0 NUC129 domain FPL PF09758.9 EGC32597.1 - 0.078 13.0 2.2 0.13 12.3 2.2 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein RhoGAP PF00620.27 EGC32598.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain DUF677 PF05055.12 EGC32599.1 - 0.028 13.3 0.1 0.034 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) TAP_C PF03943.13 EGC32599.1 - 0.18 11.5 0.1 0.66 9.7 0.0 1.9 2 0 0 2 2 2 0 TAP C-terminal domain Dicty_CTDC PF00526.18 EGC32601.1 - 0.0054 16.6 10.4 0.0054 16.6 10.4 5.9 6 1 0 6 6 6 1 Dictyostelium (slime mold) repeat DUF1772 PF08592.11 EGC32602.1 - 2.1e-21 76.7 0.0 2.7e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) DUF202 PF02656.15 EGC32602.1 - 1.1 9.8 3.2 1.2 9.6 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ERG2_Sigma1R PF04622.12 EGC32603.1 - 6.8e-61 205.3 0.1 8.3e-61 205.0 0.1 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NS3_envE PF02723.14 EGC32603.1 - 0.026 14.6 1.0 0.052 13.6 1.0 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E F-box-like PF12937.7 EGC32605.1 - 0.0031 17.4 3.0 0.0048 16.8 0.4 2.4 2 0 0 2 2 2 1 F-box-like Ndr PF03096.14 EGC32606.1 - 1.2e-73 247.3 0.0 1.5e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_1 PF00561.20 EGC32606.1 - 2e-07 30.9 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC32606.1 - 0.00073 18.9 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Serine aminopeptidase, S33 EIAV_GP90 PF00971.18 EGC32606.1 - 0.0074 15.0 0.0 0.01 14.6 0.0 1.1 1 0 0 1 1 1 1 EIAV coat protein, gp90 AAA PF00004.29 EGC32607.1 - 7.9e-41 139.6 0.0 1.4e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGC32607.1 - 8e-09 35.3 0.3 1.7e-08 34.3 0.3 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGC32607.1 - 1.8e-08 34.1 0.1 3.2e-08 33.2 0.1 1.4 1 0 0 1 1 1 1 AAA+ lid domain AAA_22 PF13401.6 EGC32607.1 - 1.9e-06 28.2 0.6 0.0013 19.1 0.2 2.6 2 1 0 2 2 1 1 AAA domain AAA_2 PF07724.14 EGC32607.1 - 1.3e-05 25.4 0.0 3.2e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGC32607.1 - 1.5e-05 24.3 0.1 3.9e-05 22.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.14 EGC32607.1 - 8.3e-05 22.6 0.7 0.00049 20.1 0.2 2.5 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGC32607.1 - 0.00022 20.5 0.0 0.51 9.5 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_16 PF13191.6 EGC32607.1 - 0.00025 21.5 0.1 0.003 18.0 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RuvB_N PF05496.12 EGC32607.1 - 0.00099 18.9 0.0 0.0021 17.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain ATPase PF06745.13 EGC32607.1 - 0.0051 16.2 0.1 0.24 10.7 0.1 2.3 1 1 1 2 2 2 1 KaiC AAA_25 PF13481.6 EGC32607.1 - 0.0061 16.2 0.6 1.5 8.4 0.1 2.3 1 1 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGC32607.1 - 0.0086 15.8 0.1 0.12 12.0 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain IstB_IS21 PF01695.17 EGC32607.1 - 0.014 15.2 0.0 0.027 14.2 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EGC32607.1 - 0.015 15.7 0.0 0.046 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase TIP49 PF06068.13 EGC32607.1 - 0.019 14.2 0.0 0.039 13.1 0.0 1.5 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_3 PF07726.11 EGC32607.1 - 0.027 14.3 0.0 0.081 12.8 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC32607.1 - 0.037 14.2 0.0 0.068 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGC32607.1 - 0.043 13.3 0.0 0.32 10.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGC32607.1 - 0.047 13.4 0.1 0.15 11.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC32607.1 - 0.048 13.6 0.1 0.22 11.4 0.0 2.0 1 1 1 2 2 2 0 NACHT domain TsaE PF02367.17 EGC32607.1 - 0.051 13.6 0.0 0.094 12.7 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PhoH PF02562.16 EGC32607.1 - 0.058 12.8 0.2 0.27 10.7 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Mg_chelatase PF01078.21 EGC32607.1 - 0.079 12.3 0.0 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGC32607.1 - 0.089 13.0 0.0 0.17 12.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Prot_ATP_OB_N PF17758.1 EGC32607.1 - 0.11 12.1 1.9 0.19 11.4 0.1 2.3 3 0 0 3 3 2 0 Proteasomal ATPase OB N-terminal domain AAA_18 PF13238.6 EGC32607.1 - 0.15 12.6 0.5 0.49 10.9 0.0 2.2 3 0 0 3 3 2 0 AAA domain MMS1_N PF10433.9 EGC32608.1 - 2.2e-65 221.2 12.7 2.2e-65 221.2 12.7 2.4 2 0 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term B_lectin PF01453.24 EGC32608.1 - 1.7 9.2 11.0 1.3 9.6 1.4 4.3 4 1 0 4 4 4 0 D-mannose binding lectin FNIP PF05725.12 EGC32609.1 - 2.2e-25 88.5 58.7 1.2e-09 38.1 0.8 10.7 7 3 3 10 10 10 8 FNIP Repeat ketoacyl-synt PF00109.26 EGC32610.1 - 3.3e-60 203.8 0.0 5.2e-60 203.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32610.1 - 4.6e-49 167.6 0.0 1e-48 166.5 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGC32610.1 - 5.9e-34 117.4 0.0 2e-33 115.7 0.0 1.9 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC32610.1 - 6.6e-29 100.3 0.0 1.2e-28 99.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32610.1 - 1.1e-24 87.4 0.0 1.5e-22 80.4 0.0 2.9 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGC32610.1 - 7.8e-23 81.2 0.0 1.2e-22 80.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC32610.1 - 7.1e-19 68.4 2.8 1e-17 64.7 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC32610.1 - 4.2e-17 62.6 0.0 1.5e-16 60.8 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGC32610.1 - 7.3e-09 35.7 0.0 1.7e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32610.1 - 1.4e-08 35.3 0.0 4.1e-08 33.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC32610.1 - 1.5e-06 28.8 0.0 4.3e-06 27.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32610.1 - 6.1e-06 26.1 0.4 4e-05 23.5 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC32610.1 - 4.9e-05 24.4 0.0 0.00021 22.4 0.0 2.2 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC32610.1 - 0.0026 17.6 0.0 0.0095 15.8 0.0 1.9 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC32610.1 - 0.0037 16.7 0.0 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PALP PF00291.25 EGC32610.1 - 0.18 11.2 0.0 0.38 10.1 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme SK_channel PF03530.14 EGC32611.1 - 1.7e-06 28.0 2.5 1.7e-06 28.0 2.5 2.4 2 1 0 2 2 2 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.16 EGC32611.1 - 0.013 15.4 6.4 0.013 15.4 6.4 2.2 2 1 0 2 2 2 0 Ion channel Lig_chan PF00060.26 EGC32611.1 - 0.16 11.8 0.1 0.16 11.8 0.1 2.2 3 1 0 3 3 3 0 Ligand-gated ion channel Cupin_8 PF13621.6 EGC32612.1 - 1.1e-17 64.6 0.0 1.1e-17 64.6 0.0 3.2 3 1 1 4 4 4 1 Cupin-like domain JmjC PF02373.22 EGC32612.1 - 4.3e-16 59.4 2.2 1.1e-15 58.1 0.0 2.9 2 0 0 2 2 2 1 JmjC domain, hydroxylase APH PF01636.23 EGC32612.1 - 0.018 15.0 0.0 6 6.7 0.0 2.3 2 0 0 2 2 2 0 Phosphotransferase enzyme family PH PF00169.29 EGC32613.1 - 5.9e-11 42.8 1.2 5.9e-11 42.8 1.2 3.6 4 0 0 4 4 4 1 PH domain PH_3 PF14593.6 EGC32613.1 - 3.6e-07 30.2 1.4 3.6e-07 30.2 1.4 2.8 2 1 0 2 2 2 1 PH domain VWA_2 PF13519.6 EGC32613.1 - 1.7e-06 28.6 0.0 6e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 EGC32613.1 - 3.4e-06 26.7 0.1 1.3e-05 24.9 0.1 2.1 1 0 0 1 1 1 1 Ubiquitin family PH_8 PF15409.6 EGC32613.1 - 0.01 16.1 0.7 0.01 16.1 0.7 3.0 4 0 0 4 4 4 0 Pleckstrin homology domain PH_11 PF15413.6 EGC32613.1 - 0.038 14.4 0.9 0.038 14.4 0.9 3.6 4 0 0 4 4 4 0 Pleckstrin homology domain Glyco_hydro_25 PF01183.20 EGC32614.1 - 7.9e-10 39.2 0.0 9e-10 39.0 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Pkinase PF00069.25 EGC32615.1 - 2.5e-62 210.6 0.0 4.6e-62 209.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32615.1 - 2.4e-39 135.2 0.0 1.1e-35 123.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC32615.1 - 0.00011 21.7 0.0 0.00032 20.1 0.0 1.7 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGC32615.1 - 0.00016 20.6 2.2 0.00078 18.3 2.2 2.1 1 1 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGC32615.1 - 0.15 11.9 0.0 0.31 10.9 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Presenilin PF01080.17 EGC32615.1 - 8.8 5.0 12.2 4.1 6.1 8.9 2.0 2 0 0 2 2 2 0 Presenilin Thioredox_DsbH PF03190.15 EGC32616.1 - 7.5e-68 227.6 0.2 2.6e-67 225.8 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.6 EGC32616.1 - 1.6e-06 28.2 0.0 3.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.13 EGC32616.1 - 2.3e-06 27.2 2.3 0.0013 18.3 0.1 3.6 3 1 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus DUF1084 PF06454.11 EGC32617.1 - 4.6e-07 29.5 33.8 1.1e-06 28.2 33.8 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) ETRAMP PF09716.10 EGC32617.1 - 0.0024 17.9 0.2 2.3 8.4 0.0 3.1 2 1 0 2 2 2 2 Malarial early transcribed membrane protein (ETRAMP) zf-RING_2 PF13639.6 EGC32619.1 - 1e-10 41.7 10.8 1.7e-10 41.1 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC32619.1 - 1.8e-08 34.1 7.4 2.7e-08 33.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC32619.1 - 1.9e-08 34.0 11.7 3.4e-08 33.2 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC32619.1 - 2.9e-07 30.7 10.0 6.1e-07 29.6 10.0 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC32619.1 - 3.3e-07 30.1 11.5 5.9e-07 29.2 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC32619.1 - 3.2e-05 23.7 6.0 5.8e-05 22.9 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC32619.1 - 0.00024 21.0 9.3 0.0004 20.3 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC32619.1 - 0.0049 16.9 6.5 0.011 15.8 6.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC32619.1 - 0.0056 16.5 10.4 0.011 15.5 10.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC32619.1 - 0.011 15.9 5.0 0.037 14.2 5.0 1.9 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC32619.1 - 0.029 14.5 10.8 0.059 13.5 9.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC32619.1 - 0.047 13.8 4.6 0.099 12.7 4.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.21 EGC32619.1 - 0.065 13.5 12.1 0.086 13.1 10.7 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 EGC32619.1 - 0.071 13.2 7.3 0.14 12.3 7.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 EGC32619.1 - 0.09 12.5 5.6 0.19 11.5 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC32619.1 - 0.54 9.9 8.7 0.89 9.2 8.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RVT PF13966.6 EGC32619.1 - 0.64 10.8 6.4 0.2 12.4 0.8 2.7 3 0 0 3 3 2 0 zinc-binding in reverse transcriptase TACC_C PF05010.14 EGC32619.1 - 0.69 9.7 32.6 0.061 13.1 17.0 2.3 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Gal4_dimer PF03902.13 EGC32619.1 - 0.95 9.7 0.1 0.95 9.7 0.1 2.9 3 1 0 3 3 1 0 Gal4-like dimerisation domain Monooxygenase_B PF04744.12 EGC32619.1 - 1.6 7.5 3.5 0.35 9.7 0.2 1.5 2 0 0 2 2 2 0 Monooxygenase subunit B protein zf-P11 PF03854.14 EGC32619.1 - 3.6 7.3 7.2 9.7 5.9 7.2 1.7 1 1 0 1 1 1 0 P-11 zinc finger TctB PF07331.11 EGC32621.1 - 0.0077 16.5 0.2 0.11 12.8 0.4 2.4 1 1 1 2 2 2 1 Tripartite tricarboxylate transporter TctB family MARVEL PF01284.23 EGC32621.1 - 0.086 12.9 6.8 2.2 8.3 7.2 2.5 1 1 0 1 1 1 0 Membrane-associating domain VIT1 PF01988.19 EGC32621.1 - 0.094 12.6 0.4 3.8 7.3 0.4 2.5 1 1 0 1 1 1 0 VIT family DUF21 PF01595.20 EGC32621.1 - 0.32 10.7 7.1 0.046 13.4 1.0 2.2 2 1 0 2 2 2 0 Cyclin M transmembrane N-terminal domain DUF3619 PF12279.8 EGC32621.1 - 0.59 10.5 1.3 58 4.0 0.1 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3619) MRAP PF15183.6 EGC32621.1 - 2.5 8.1 7.6 2.6 8.0 0.1 3.6 3 1 1 4 4 4 0 Melanocortin-2 receptor accessory protein family Virul_fac_BrkB PF03631.15 EGC32621.1 - 2.6 7.6 10.4 0.082 12.5 1.3 2.2 2 1 0 2 2 2 0 Virulence factor BrkB RNase_H2-Ydr279 PF09468.10 EGC32622.1 - 2.2e-11 44.2 1.8 5.5e-11 42.9 1.8 1.7 1 0 0 1 1 1 1 Ydr279p protein family (RNase H2 complex component) wHTH domain Ydr279_N PF17745.1 EGC32622.1 - 1.6e-09 37.9 0.1 5.3e-09 36.2 0.1 1.9 1 0 0 1 1 1 1 Ydr279p protein triple barrel domain RPS31 PF17067.5 EGC32623.1 - 0.012 15.7 2.4 0.023 14.9 2.4 1.4 1 0 0 1 1 1 0 Ribosomal protein S31e DUF3446 PF11928.8 EGC32623.1 - 0.027 14.8 8.5 0.077 13.3 8.5 1.8 1 0 0 1 1 1 0 Early growth response N-terminal domain F-box-like PF12937.7 EGC32623.1 - 0.067 13.1 0.3 1.7 8.6 0.0 2.9 3 0 0 3 3 3 0 F-box-like RIH_assoc PF08454.11 EGC32623.1 - 0.28 11.0 13.7 0.022 14.6 4.2 2.5 2 0 0 2 2 2 0 RyR and IP3R Homology associated SSP160 PF06933.11 EGC32623.1 - 2.6 6.2 11.4 3.6 5.7 11.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PMBR PF09373.10 EGC32623.1 - 4.4 7.6 11.7 3.3 8.0 0.7 4.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat Yip1 PF04893.17 EGC32624.1 - 0.0027 17.5 0.0 0.1 12.3 0.0 3.1 4 1 0 4 4 4 1 Yip1 domain Zip PF02535.22 EGC32624.1 - 0.0085 15.4 0.1 0.0085 15.4 0.1 4.1 3 1 0 3 3 3 1 ZIP Zinc transporter Glycophorin_A PF01102.18 EGC32624.1 - 0.021 15.1 0.1 0.021 15.1 0.1 4.3 6 0 0 6 6 6 0 Glycophorin A Presenilin PF01080.17 EGC32624.1 - 0.044 12.5 0.2 0.044 12.5 0.2 5.1 3 1 1 4 4 4 0 Presenilin Neur_chan_memb PF02932.16 EGC32624.1 - 0.16 12.0 0.0 0.16 12.0 0.0 3.7 2 1 1 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region ECH_2 PF16113.5 EGC32625.1 - 2.3e-71 241.0 0.0 3e-71 240.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGC32625.1 - 7.3e-13 48.4 0.0 2.1e-12 46.9 0.0 1.7 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase Peptidase_M73 PF12389.8 EGC32625.1 - 0.11 12.3 0.8 0.24 11.2 0.8 1.5 1 0 0 1 1 1 0 Camelysin metallo-endopeptidase DUF3522 PF12036.8 EGC32626.1 - 6.3e-44 150.5 9.1 7.9e-44 150.2 9.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) Ceramidase PF05875.12 EGC32626.1 - 0.14 11.6 0.1 0.14 11.6 0.1 2.7 2 1 1 3 3 3 0 Ceramidase HlyIII PF03006.20 EGC32626.1 - 0.18 11.5 13.3 1 9.0 13.3 2.2 1 1 0 1 1 1 0 Haemolysin-III related FNIP PF05725.12 EGC32628.1 - 3.4e-197 638.5 94.2 4.4e-15 55.6 0.2 14.0 2 2 12 18 18 18 18 FNIP Repeat Phage_min_tail PF05939.13 EGC32628.1 - 0.00096 19.5 0.0 37 4.8 0.0 6.4 6 3 2 9 9 9 1 Phage minor tail protein PIF1 PF05970.14 EGC32628.1 - 2.3 7.3 6.6 48 3.0 0.0 4.8 5 1 1 6 6 6 0 PIF1-like helicase FNIP PF05725.12 EGC32629.1 - 5.1e-192 621.9 79.5 1.9e-16 59.9 0.1 15.5 9 3 5 17 17 17 17 FNIP Repeat Phage_min_tail PF05939.13 EGC32629.1 - 0.00038 20.8 0.0 61 4.1 0.0 7.5 5 3 5 10 10 10 1 Phage minor tail protein Intein_splicing PF14890.6 EGC32630.1 - 0.054 13.4 1.2 0.08 12.9 1.2 1.3 1 1 0 1 1 1 0 Intein splicing domain Peptidase_S8 PF00082.22 EGC32631.1 - 1.1e-35 123.4 0.9 1.8e-35 122.7 0.9 1.3 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.13 EGC32631.1 - 0.051 13.9 15.2 0.14 12.6 15.2 1.8 1 0 0 1 1 1 0 EGF-like domain Toxin_23 PF08093.11 EGC32631.1 - 5.9 7.1 11.4 15 5.8 11.4 1.6 1 0 0 1 1 1 0 Magi 5 toxic peptide family ELP6 PF09807.9 EGC32632.1 - 3.2e-29 102.1 0.1 2.3e-13 50.2 0.0 2.8 2 1 0 2 2 2 2 Elongation complex protein 6 Elong_Iki1 PF10483.9 EGC32632.1 - 6.3e-08 32.5 0.2 3.2e-06 26.9 0.1 2.1 2 0 0 2 2 2 2 Elongator subunit Iki1 GpcrRhopsn4 PF10192.9 EGC32632.1 - 0.032 13.7 0.1 0.073 12.5 0.1 1.5 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain RhoGAP PF00620.27 EGC32633.1 - 2.9e-05 23.9 0.6 6e-05 22.9 0.6 1.5 1 1 0 1 1 1 1 RhoGAP domain RA PF00788.23 EGC32633.1 - 0.0022 18.6 0.0 0.005 17.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain FERM_f0 PF16511.5 EGC32633.1 - 0.0041 17.4 0.0 0.0083 16.4 0.0 1.5 1 0 0 1 1 1 1 N-terminal or F0 domain of Talin-head FERM Ras_bdg_2 PF14847.6 EGC32633.1 - 0.077 13.3 0.2 0.46 10.8 0.0 2.1 2 0 0 2 2 2 0 Ras-binding domain of Byr2 NADHdh_A3 PF14987.6 EGC32633.1 - 0.13 12.6 0.2 1.1 9.6 0.1 2.3 2 0 0 2 2 2 0 NADH dehydrogenase 1 alpha subcomplex subunit 3 SPA PF08616.10 EGC32635.1 - 3.4e-32 110.8 0.0 2.1e-31 108.2 0.0 2.4 2 0 0 2 2 2 1 Stabilization of polarity axis Afi1 PF07792.12 EGC32635.1 - 3.9e-22 79.2 11.8 4.4e-21 75.8 0.6 2.7 2 0 0 2 2 2 2 Docking domain of Afi1 for Arf3 in vesicle trafficking Avl9 PF09794.9 EGC32635.1 - 3.5e-10 39.1 5.8 0.056 12.1 0.0 4.5 2 2 2 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.9 EGC32635.1 - 0.00081 19.1 8.3 0.0041 16.7 0.0 4.1 3 2 1 4 4 4 1 Uncharacterized conserved protein (DUF2347) SPX PF03105.19 EGC32635.1 - 0.041 13.8 15.5 0.77 9.6 5.7 2.4 2 0 0 2 2 2 0 SPX domain DUF3439 PF11921.8 EGC32635.1 - 0.23 11.4 6.4 0.73 9.8 6.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Zip PF02535.22 EGC32635.1 - 3.6 6.7 8.4 1.5 8.0 1.2 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter FAM60A PF15396.6 EGC32635.1 - 8.6 6.3 10.4 3.6 7.5 0.6 2.7 2 0 0 2 2 2 0 Protein Family FAM60A Glycolytic PF00274.19 EGC32636.1 - 2.4e-166 552.7 0.0 2.7e-166 552.5 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I WD40 PF00400.32 EGC32637.1 - 1e-20 73.7 18.6 1.4e-06 28.9 0.0 5.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32637.1 - 1.1e-11 44.9 0.1 0.26 11.6 0.0 5.2 2 1 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC32637.1 - 6.8e-05 22.0 0.1 0.65 8.9 0.0 3.6 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein PD40 PF07676.12 EGC32637.1 - 0.00072 19.4 4.8 0.8 9.7 0.1 3.8 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Crystall_3 PF08964.10 EGC32638.1 - 4.9e-31 106.7 0.0 7.8e-31 106.1 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Membrane_bind PF14564.6 EGC32638.1 - 2.8e-08 34.2 0.2 4.1e-08 33.6 0.2 1.3 1 0 0 1 1 1 1 Membrane binding VRR_NUC PF08774.11 EGC32639.1 - 0.016 15.2 0.2 0.086 12.9 0.0 2.2 2 0 0 2 2 2 0 VRR-NUC domain HJURP_C PF12347.8 EGC32640.1 - 0.021 14.9 0.3 0.021 14.9 0.3 2.4 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat DUF5362 PF17319.2 EGC32640.1 - 0.43 10.5 1.1 20 5.1 0.1 2.4 2 0 0 2 2 2 0 Family of unknown function (DUF5362) GNAT_acetyltran PF12746.7 EGC32640.1 - 2.2 7.8 11.6 3.2 7.3 9.6 2.0 1 1 1 2 2 2 0 GNAT acetyltransferase VIT1 PF01988.19 EGC32641.1 - 2.4e-49 168.1 0.3 2.8e-49 167.9 0.3 1.1 1 0 0 1 1 1 1 VIT family DUF2157 PF09925.9 EGC32641.1 - 0.0043 16.9 0.0 0.0093 15.8 0.0 1.6 2 1 0 2 2 2 1 Predicted membrane protein (DUF2157) SieB PF14163.6 EGC32641.1 - 0.021 14.3 2.1 0.021 14.3 0.0 2.0 2 1 0 2 2 2 0 Super-infection exclusion protein B RP853 PF17542.2 EGC32641.1 - 0.035 13.2 0.1 0.05 12.7 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized RP853 DUF2207 PF09972.9 EGC32641.1 - 0.079 11.7 3.0 11 4.7 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) MEA1 PF06910.11 EGC32642.1 - 0.026 15.2 10.8 0.91 10.2 9.5 2.7 1 1 1 2 2 2 0 Male enhanced antigen 1 (MEA1) LSM PF01423.22 EGC32643.1 - 5.6e-10 38.8 0.0 1.3e-09 37.6 0.0 1.7 1 0 0 1 1 1 1 LSM domain SOG2 PF10428.9 EGC32643.1 - 0.00099 18.4 3.0 0.00099 18.4 3.0 1.1 1 0 0 1 1 1 1 RAM signalling pathway protein TFIIA PF03153.13 EGC32643.1 - 0.001 19.1 6.7 0.0011 19.1 6.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF3439 PF11921.8 EGC32643.1 - 0.0057 16.6 2.5 0.0084 16.1 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Maf1 PF09174.10 EGC32643.1 - 0.013 15.7 2.6 0.019 15.1 2.6 1.3 1 0 0 1 1 1 0 Maf1 regulator Ndc1_Nup PF09531.10 EGC32643.1 - 0.028 13.1 4.8 0.03 13.1 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup SRA PF18491.1 EGC32643.1 - 0.029 14.5 0.3 0.074 13.2 0.3 1.7 1 0 0 1 1 1 0 SET and RING associated domain Spt20 PF12090.8 EGC32643.1 - 0.29 10.7 22.1 0.53 9.9 22.1 1.4 1 0 0 1 1 1 0 Spt20 family Mucin PF01456.17 EGC32643.1 - 1 9.4 14.8 1.5 8.9 14.8 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1180 PF06679.12 EGC32643.1 - 1.7 9.0 7.4 2.6 8.4 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) DUF1387 PF07139.11 EGC32643.1 - 5.1 6.7 9.1 7.9 6.1 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) NTP_transf_2 PF01909.23 EGC32644.1 - 2e-05 24.8 0.2 0.00015 22.0 0.1 2.6 2 0 0 2 2 2 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.11 EGC32644.1 - 0.00062 20.0 0.2 0.0049 17.1 0.0 2.5 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain Polbeta PF18765.1 EGC32644.1 - 0.0025 17.8 0.2 0.049 13.7 0.0 3.4 2 0 0 2 2 2 1 Polymerase beta, Nucleotidyltransferase OAS1_C PF10421.9 EGC32644.1 - 0.027 14.0 0.1 0.057 12.9 0.1 1.5 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus AI-2E_transport PF01594.16 EGC32644.1 - 3 6.9 9.1 0.25 10.4 0.6 2.5 2 0 0 2 2 2 0 AI-2E family transporter Thg1 PF04446.12 EGC32645.1 - 1.1e-27 96.5 0.3 1.1e-27 96.5 0.3 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Ribosomal_S2 PF00318.20 EGC32646.1 - 0.077 12.2 0.0 0.077 12.2 0.0 1.0 1 0 0 1 1 1 0 Ribosomal protein S2 Ecm29 PF13001.7 EGC32647.1 - 9.6e-132 440.2 8.6 9.6e-132 440.2 8.6 4.6 5 1 0 5 5 5 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.7 EGC32647.1 - 1.4e-10 41.6 6.4 0.012 16.2 0.0 8.6 8 1 1 9 9 9 2 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EGC32647.1 - 4.4e-05 22.7 3.1 0.0041 16.3 0.0 4.5 6 1 0 6 6 6 1 Interferon-related developmental regulator (IFRD) HEAT PF02985.22 EGC32647.1 - 0.00022 21.2 0.0 25 5.5 0.0 6.1 5 0 0 5 5 5 0 HEAT repeat DUF3730 PF12530.8 EGC32647.1 - 0.0014 18.2 3.0 0.37 10.3 0.4 3.9 3 1 0 3 3 3 2 Protein of unknown function (DUF3730) Cnd1 PF12717.7 EGC32647.1 - 0.0076 16.3 28.3 0.38 10.8 3.7 8.0 7 1 1 8 8 8 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGC32647.1 - 0.012 15.9 0.0 4.5 7.7 0.0 4.9 6 0 0 6 6 5 0 HEAT repeats HEAT_EZ PF13513.6 EGC32647.1 - 0.015 15.8 0.0 1.1e+02 3.5 0.0 5.6 7 0 0 7 7 7 0 HEAT-like repeat SapB_2 PF03489.17 EGC32647.1 - 0.016 15.3 5.2 34 4.7 0.0 5.8 6 0 0 6 6 6 0 Saposin-like type B, region 2 TIP120 PF08623.10 EGC32647.1 - 0.035 13.9 5.2 0.43 10.3 0.5 4.2 4 1 0 4 4 4 0 TATA-binding protein interacting (TIP20) DUF5601 PF18151.1 EGC32647.1 - 0.18 12.1 4.4 0.18 12.1 0.1 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) DUF4523 PF15023.6 EGC32649.1 - 0.004 17.0 2.8 0.0048 16.7 2.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4523) DUF4564 PF15169.6 EGC32650.1 - 1.9e-61 207.0 2.4 2.5e-61 206.6 2.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) EbsA PF17255.2 EGC32650.1 - 0.036 14.4 0.1 0.064 13.6 0.1 1.5 1 0 0 1 1 1 0 EbsA-like protein Claudin_3 PF06653.11 EGC32650.1 - 0.042 13.8 0.0 0.053 13.5 0.0 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like Alg6_Alg8 PF03155.15 EGC32650.1 - 0.05 12.6 0.1 0.061 12.3 0.1 1.1 1 0 0 1 1 1 0 ALG6, ALG8 glycosyltransferase family zf-CSL PF05207.13 EGC32652.1 - 0.00012 21.7 0.5 0.00026 20.6 0.5 1.6 1 0 0 1 1 1 1 CSL zinc finger Bac_RepA_C PF18008.1 EGC32652.1 - 0.16 12.3 4.3 0.2 12.1 3.4 1.6 1 1 0 1 1 1 0 Replication initiator protein A C-terminal domain DUF2890 PF11081.8 EGC32653.1 - 0.0034 17.5 4.5 0.0034 17.5 4.5 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2890) SAP PF02037.27 EGC32653.1 - 0.0037 17.0 0.8 0.29 10.9 0.5 2.5 2 0 0 2 2 2 1 SAP domain BUD22 PF09073.10 EGC32653.1 - 0.0058 16.0 31.5 0.14 11.5 21.7 2.1 2 0 0 2 2 2 2 BUD22 BSP_II PF05432.11 EGC32653.1 - 0.56 9.9 40.2 0.29 10.8 16.1 3.1 3 0 0 3 3 3 0 Bone sialoprotein II (BSP-II) Anoctamin PF04547.12 EGC32653.1 - 0.71 8.6 4.8 0.32 9.8 0.3 2.1 2 0 0 2 2 2 0 Calcium-activated chloride channel Menin PF05053.13 EGC32653.1 - 4.6 5.5 20.8 0.48 8.7 13.8 2.1 2 0 0 2 2 2 0 Menin ubiquitin PF00240.23 EGC32654.1 - 7.7e-101 329.9 13.4 4.6e-33 112.8 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.8 EGC32654.1 - 2.1e-47 158.8 13.0 3.3e-15 55.7 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC32654.1 - 2.8e-17 62.9 6.1 0.0004 20.8 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC32654.1 - 3.4e-11 43.4 4.7 0.025 14.9 0.1 3.1 3 0 0 3 3 3 3 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC32654.1 - 3.4e-11 42.9 2.5 0.036 14.0 0.1 3.2 3 0 0 3 3 3 3 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC32654.1 - 1.8e-10 40.9 0.7 0.13 12.4 0.0 3.9 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC32654.1 - 2.1e-09 37.9 0.3 0.18 12.4 0.1 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain Ubiquitin_4 PF18036.1 EGC32654.1 - 6.4e-06 26.1 14.5 17 5.6 0.0 6.0 6 0 0 6 6 6 0 Ubiquitin-like domain Sde2_N_Ubi PF13019.6 EGC32654.1 - 9.8e-06 25.5 0.1 2.9 7.7 0.0 3.1 1 1 2 3 3 3 3 Silencing defective 2 N-terminal ubiquitin domain DUF2870 PF11069.8 EGC32654.1 - 0.0002 21.7 0.1 20 5.6 0.0 3.9 3 3 0 3 3 3 0 Protein of unknown function (DUF2870) Big_3_3 PF13750.6 EGC32654.1 - 0.00046 19.9 0.0 13 5.4 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Methyltrans_RNA PF04452.14 EGC32654.1 - 0.00051 19.5 0.2 1 8.7 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase DUF3861 PF12977.7 EGC32654.1 - 0.0011 19.1 0.5 21 5.4 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3861) DUF3435 PF11917.8 EGC32654.1 - 0.0028 16.6 0.2 13 4.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) YcgR_2 PF12945.7 EGC32654.1 - 0.0042 17.2 3.1 20 5.4 0.1 3.3 3 0 0 3 3 3 0 Flagellar protein YcgR DUF969 PF06149.12 EGC32654.1 - 0.005 16.3 0.0 12 5.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF969) ACT_5 PF13710.6 EGC32654.1 - 0.0059 16.4 1.3 29 4.6 0.0 3.3 3 0 0 3 3 3 0 ACT domain N1221 PF07923.13 EGC32654.1 - 0.0067 15.6 0.4 22 4.1 0.0 3.0 3 0 0 3 3 3 0 N1221-like protein UDP-g_GGTase PF06427.11 EGC32654.1 - 0.0086 16.2 3.4 4.3 7.5 0.1 3.1 4 0 0 4 4 3 2 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 EGC32654.1 - 0.0099 16.6 0.0 70 4.3 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig domain Corona_NS2A PF05213.12 EGC32654.1 - 0.013 14.9 0.0 26 4.1 0.0 3.0 3 0 0 3 3 3 0 Coronavirus NS2A protein Imm12 PF15560.6 EGC32654.1 - 0.023 14.7 0.6 48 3.9 0.0 3.1 3 0 0 3 3 3 0 Immunity protein 12 ORF11CD3 PF10549.9 EGC32654.1 - 0.023 14.8 0.0 62 3.8 0.0 4.3 6 0 0 6 6 6 0 ORF11CD3 domain Raf1_HTH PF18579.1 EGC32654.1 - 0.031 14.0 0.1 69 3.3 0.0 3.2 3 0 0 3 3 3 0 Rubisco accumulation factor 1 helix turn helix domain ACT_4 PF13291.6 EGC32654.1 - 0.061 13.9 0.1 1.2e+02 3.3 0.0 3.2 3 0 0 3 3 3 0 ACT domain NEAT PF05031.12 EGC32654.1 - 0.095 13.3 3.0 18 6.0 3.0 3.0 1 1 1 2 2 2 0 Iron Transport-associated domain Myosin_N PF02736.19 EGC32654.1 - 0.14 12.0 2.6 76 3.3 0.0 4.4 3 0 0 3 3 3 0 Myosin N-terminal SH3-like domain DMA PF03474.14 EGC32654.1 - 0.43 10.2 1.7 1.1e+02 2.5 0.0 3.3 3 0 0 3 3 3 0 DMRTA motif HcyBio PF01837.16 EGC32654.1 - 0.43 9.4 3.0 14 4.4 0.1 2.7 3 0 0 3 3 3 0 Homocysteine biosynthesis enzyme, sulfur-incorporation DAP_epimerase PF01678.19 EGC32655.1 - 1.4e-37 128.6 3.0 5.1e-20 71.9 0.1 2.7 2 1 0 2 2 2 2 Diaminopimelate epimerase DUF1242 PF06842.12 EGC32656.1 - 7.5e-14 51.2 0.8 1.2e-13 50.6 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF2207 PF09972.9 EGC32657.1 - 0.22 10.3 0.3 0.24 10.1 0.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF4887 PF16228.5 EGC32658.1 - 0.31 11.2 8.5 0.39 10.9 8.5 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4887) PCI PF01399.27 EGC32659.1 - 8.7e-20 71.2 3.8 5e-19 68.8 0.1 3.1 2 1 0 2 2 2 1 PCI domain Rpn3_C PF08375.11 EGC32659.1 - 1.6e-19 70.1 1.3 3.4e-19 69.0 1.3 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal CSN8_PSD8_EIF3K PF10075.9 EGC32659.1 - 0.00054 20.0 2.6 0.0015 18.5 0.3 2.7 2 1 0 2 2 2 1 CSN8/PSMD8/EIF3K family TPR_2 PF07719.17 EGC32659.1 - 0.11 12.7 0.5 0.31 11.3 0.5 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF885 PF05960.11 EGC32660.1 - 3.1e-140 469.3 0.0 4.1e-140 468.9 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) DUF4089 PF13318.6 EGC32660.1 - 0.14 12.6 0.1 0.3 11.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4089) Mei5_like PF17021.5 EGC32660.1 - 0.34 11.0 4.2 3 7.9 0.1 3.9 4 1 1 5 5 5 0 Putative double-strand recombination repair-like YdiH PF15930.5 EGC32660.1 - 0.35 11.1 1.6 2.2 8.5 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function AAA PF00004.29 EGC32661.1 - 1.1e-98 326.8 0.0 1.4e-48 164.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC32661.1 - 2.6e-26 91.2 6.3 1.5e-12 47.1 0.5 3.6 2 2 0 2 2 2 2 AAA+ lid domain CDC48_N PF02359.18 EGC32661.1 - 1.6e-22 79.5 0.2 5.3e-22 77.8 0.2 2.0 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.12 EGC32661.1 - 6.9e-15 55.1 0.0 3.1e-06 27.0 0.0 2.8 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGC32661.1 - 8.6e-14 52.0 0.0 8e-07 29.3 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGC32661.1 - 6.2e-13 49.5 0.3 0.0003 21.2 0.0 3.9 2 2 0 2 2 2 2 AAA ATPase domain CDC48_2 PF02933.17 EGC32661.1 - 1.7e-11 43.7 0.0 4e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 AAA_5 PF07728.14 EGC32661.1 - 2.1e-11 44.0 0.1 1e-05 25.6 0.0 3.5 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGC32661.1 - 2.2e-11 44.1 0.0 1.5e-05 25.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EGC32661.1 - 3.1e-10 40.4 0.3 0.0055 17.0 0.1 3.9 2 2 1 3 3 3 2 AAA domain AAA_14 PF13173.6 EGC32661.1 - 3.7e-09 36.7 0.0 0.00034 20.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGC32661.1 - 2.9e-08 33.3 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Vps4_C PF09336.10 EGC32661.1 - 3.3e-08 33.4 1.0 1.5e-06 28.1 0.1 2.7 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_18 PF13238.6 EGC32661.1 - 8.7e-08 32.8 0.0 0.013 16.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain Mg_chelatase PF01078.21 EGC32661.1 - 8.8e-08 31.8 0.4 0.0096 15.3 0.1 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGC32661.1 - 1.2e-07 32.1 0.0 0.0075 16.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase ATPase_2 PF01637.18 EGC32661.1 - 1e-06 28.8 0.1 0.067 13.1 0.0 3.2 3 1 0 3 3 2 2 ATPase domain predominantly from Archaea IstB_IS21 PF01695.17 EGC32661.1 - 1e-06 28.6 0.0 0.055 13.2 0.0 2.6 2 1 0 2 2 2 2 IstB-like ATP binding protein Viral_helicase1 PF01443.18 EGC32661.1 - 1.1e-06 28.5 0.0 0.0019 18.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.27 EGC32661.1 - 1.2e-06 29.0 0.2 0.013 16.0 0.0 3.2 3 1 0 3 3 2 2 ABC transporter Bac_DnaA PF00308.18 EGC32661.1 - 3e-06 27.3 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_28 PF13521.6 EGC32661.1 - 4.3e-06 27.1 0.0 0.2 11.9 0.0 3.0 3 0 0 3 3 2 2 AAA domain Parvo_NS1 PF01057.17 EGC32661.1 - 5.4e-06 25.7 0.1 0.031 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Zeta_toxin PF06414.12 EGC32661.1 - 6.2e-06 25.6 0.2 0.086 12.1 0.0 3.1 3 0 0 3 3 3 2 Zeta toxin AAA_25 PF13481.6 EGC32661.1 - 6.8e-06 25.8 1.1 0.86 9.1 0.0 3.8 2 2 2 4 4 4 2 AAA domain NACHT PF05729.12 EGC32661.1 - 1e-05 25.5 0.2 0.29 11.1 0.0 3.3 3 1 1 4 4 4 2 NACHT domain AAA_7 PF12775.7 EGC32661.1 - 1.5e-05 24.6 0.0 0.11 12.0 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region AAA_17 PF13207.6 EGC32661.1 - 1.6e-05 25.3 0.0 0.19 12.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGC32661.1 - 2.8e-05 23.9 0.0 0.06 13.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain ATPase PF06745.13 EGC32661.1 - 2.9e-05 23.5 0.2 3 7.1 0.0 3.3 3 0 0 3 3 3 1 KaiC TsaE PF02367.17 EGC32661.1 - 3e-05 24.0 0.0 0.2 11.7 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Rad17 PF03215.15 EGC32661.1 - 4.3e-05 23.5 0.0 0.38 10.7 0.0 2.6 2 1 0 2 2 2 2 Rad17 P-loop domain Sigma54_activat PF00158.26 EGC32661.1 - 6.8e-05 22.6 0.0 0.57 9.9 0.0 3.1 2 2 0 2 2 2 2 Sigma-54 interaction domain NB-ARC PF00931.22 EGC32661.1 - 7e-05 22.1 0.0 0.24 10.5 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain DUF815 PF05673.13 EGC32661.1 - 0.00025 20.3 0.0 0.19 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EGC32661.1 - 0.00039 20.6 0.0 1 9.5 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_3 PF07726.11 EGC32661.1 - 0.00047 20.0 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ResIII PF04851.15 EGC32661.1 - 0.0011 19.0 0.0 0.16 12.0 0.0 2.4 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Cytidylate_kin2 PF13189.6 EGC32661.1 - 0.002 18.3 0.0 0.44 10.7 0.0 2.6 2 0 0 2 2 2 1 Cytidylate kinase-like family PhoH PF02562.16 EGC32661.1 - 0.0048 16.4 0.3 1.9 7.9 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein NTPase_1 PF03266.15 EGC32661.1 - 0.0056 16.6 0.2 5.3 6.9 0.0 3.5 3 0 0 3 3 3 0 NTPase AAA_19 PF13245.6 EGC32661.1 - 0.0064 16.8 0.7 8.9 6.6 0.1 3.4 3 1 0 4 4 3 0 AAA domain TniB PF05621.11 EGC32661.1 - 0.0068 15.8 0.0 1.7 8.0 0.0 3.5 4 0 0 4 4 4 1 Bacterial TniB protein SKI PF01202.22 EGC32661.1 - 0.0094 16.1 0.0 6.5 6.9 0.0 2.6 2 0 0 2 2 2 0 Shikimate kinase AAA_11 PF13086.6 EGC32661.1 - 0.011 15.5 0.5 5.1 6.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain PduV-EutP PF10662.9 EGC32661.1 - 0.012 15.4 0.0 3.3 7.5 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_23 PF13476.6 EGC32661.1 - 0.02 15.4 0.0 12 6.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGC32661.1 - 0.022 14.0 0.0 4.8 6.3 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 EGC32661.1 - 0.058 12.3 0.7 4.7 6.0 0.0 2.5 3 0 0 3 3 2 0 AFG1-like ATPase tRNA_lig_kinase PF08303.11 EGC32661.1 - 0.071 13.2 0.0 0.47 10.5 0.0 2.2 2 0 0 2 2 2 0 tRNA ligase kinase domain Adeno_IVa2 PF02456.15 EGC32661.1 - 0.083 11.7 0.1 11 4.7 0.0 2.2 2 0 0 2 2 2 0 Adenovirus IVa2 protein Cytidylate_kin PF02224.18 EGC32661.1 - 0.088 12.5 0.0 15 5.2 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase KAP_NTPase PF07693.14 EGC32661.1 - 0.1 11.8 0.1 5.7 6.1 0.0 3.1 2 2 2 4 4 4 0 KAP family P-loop domain AAA_30 PF13604.6 EGC32661.1 - 0.11 12.2 0.1 21 4.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain Dymeclin PF09742.9 EGC32662.1 - 5.4e-149 497.5 10.1 6.5e-149 497.2 10.1 1.1 1 0 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Hid1 PF12722.7 EGC32662.1 - 2.2e-147 492.5 20.2 2.9e-147 492.1 20.2 1.2 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Zip PF02535.22 EGC32662.1 - 1.4 8.0 8.6 18 4.4 0.0 2.3 2 0 0 2 2 2 0 ZIP Zinc transporter Methyltransf_16 PF10294.9 EGC32664.1 - 1.7e-27 96.3 0.1 4.9e-26 91.5 0.1 2.3 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC32664.1 - 0.057 13.3 0.1 0.1 12.4 0.1 1.7 1 1 0 1 1 1 0 Methyltransferase domain CDC45 PF02724.14 EGC32664.1 - 0.23 9.7 15.3 0.32 9.2 15.3 1.3 1 0 0 1 1 1 0 CDC45-like protein ketoacyl-synt PF00109.26 EGC32665.1 - 4.3e-78 262.4 0.0 7.4e-78 261.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32665.1 - 1.5e-41 143.0 0.0 2.6e-41 142.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Chal_sti_synt_N PF00195.19 EGC32665.1 - 9.3e-41 139.7 0.0 1.8e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC32665.1 - 2.9e-39 133.7 0.0 8.7e-39 132.2 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32665.1 - 3e-32 112.0 0.0 7.3e-32 110.7 0.0 1.7 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC32665.1 - 5e-31 108.0 0.0 7.4e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Chal_sti_synt_C PF02797.15 EGC32665.1 - 2e-22 79.8 0.1 8.2e-22 77.8 0.0 2.2 2 0 0 2 2 1 1 Chalcone and stilbene synthases, C-terminal domain KAsynt_C_assoc PF16197.5 EGC32665.1 - 1.7e-16 60.6 0.0 6.1e-16 58.9 0.0 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_12 PF08242.12 EGC32665.1 - 2.1e-15 57.3 0.0 7.1e-15 55.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.12 EGC32665.1 - 9.8e-12 44.8 0.7 1.6e-11 44.0 0.0 1.7 2 0 0 2 2 1 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.6 EGC32665.1 - 4.6e-09 36.3 0.0 1.1e-08 35.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III_C PF08541.10 EGC32665.1 - 2.8e-08 33.8 0.0 1.6e-07 31.4 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_zinc_N_2 PF13602.6 EGC32665.1 - 8.9e-07 30.0 0.0 2.1e-06 28.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ACP_syn_III PF08545.10 EGC32665.1 - 5.9e-06 26.1 3.5 1.4e-05 24.8 0.1 2.7 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III ADH_N PF08240.12 EGC32665.1 - 1.3e-05 25.0 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC32665.1 - 1.4e-05 25.4 0.1 8.8e-05 22.8 0.1 2.4 1 1 1 2 2 2 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC32665.1 - 2.5e-05 23.8 0.9 4.6e-05 22.9 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.6 EGC32665.1 - 4.5e-05 24.1 0.0 0.00016 22.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC32665.1 - 8.7e-05 22.4 0.2 0.0012 18.7 0.0 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32665.1 - 0.00066 20.3 0.0 0.0023 18.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGC32665.1 - 0.0019 18.0 0.0 0.0056 16.4 0.0 1.7 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_28 PF02636.17 EGC32665.1 - 0.033 13.8 0.0 0.069 12.8 0.0 1.5 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Ubie_methyltran PF01209.18 EGC32665.1 - 0.036 13.4 0.0 0.11 11.8 0.0 1.8 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family BLI1 PF17324.2 EGC32665.1 - 0.12 13.0 3.1 0.29 11.8 1.1 2.8 2 0 0 2 2 1 0 BLOC-1 interactor 1 APH PF01636.23 EGC32666.1 - 4.3e-09 36.7 0.0 3.3e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC32666.1 - 0.13 11.8 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.25 EGC32667.1 - 3.7e-64 216.7 1.7 1.3e-42 146.0 0.0 3.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32667.1 - 1.3e-48 165.6 1.8 1.7e-48 165.1 0.1 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.28 EGC32667.1 - 3.2e-09 37.0 2.1 8.7e-09 35.6 0.1 3.0 2 0 0 2 2 2 1 P21-Rho-binding domain CH PF00307.31 EGC32667.1 - 5.2e-09 36.3 0.1 5.2e-09 36.3 0.1 2.9 2 0 0 2 2 2 1 Calponin homology (CH) domain C1_1 PF00130.22 EGC32667.1 - 1.3e-08 34.6 5.6 2.3e-08 33.8 5.6 1.5 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SBF2 PF12335.8 EGC32667.1 - 3.7e-07 30.0 0.3 3.7e-07 30.0 0.3 2.8 2 0 0 2 2 2 1 Myotubularin protein C1_2 PF03107.16 EGC32667.1 - 0.12 12.7 1.8 0.33 11.3 1.8 1.7 1 0 0 1 1 1 0 C1 domain PHD_4 PF16866.5 EGC32667.1 - 0.24 11.5 2.0 1.2 9.3 2.0 2.3 1 0 0 1 1 1 0 PHD-finger RasGEF_N_2 PF14663.6 EGC32667.1 - 0.34 11.3 5.0 0.28 11.6 1.5 2.9 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RCC1 PF00415.18 EGC32668.1 - 2e-67 223.6 1.7 6e-11 42.8 0.0 8.2 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC32668.1 - 1.2e-41 139.7 39.0 5.2e-10 38.9 0.4 8.9 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGC32668.1 - 4.9e-12 46.0 9.5 2.5e-11 43.8 2.5 2.9 3 0 0 3 3 3 2 BTB/POZ domain HU-HIG PF18291.1 EGC32668.1 - 0.074 13.2 0.1 0.36 10.9 0.0 2.2 2 0 0 2 2 2 0 HU domain fused to wHTH, Ig, or Glycine-rich motif BACK PF07707.15 EGC32668.1 - 0.076 13.1 4.1 0.42 10.7 0.3 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch EGF_2 PF07974.13 EGC32669.1 - 3.2e-40 136.2 312.8 6.2e-06 26.5 13.8 16.3 15 1 0 15 15 15 14 EGF-like domain TIG PF01833.24 EGC32669.1 - 3.8e-07 30.1 10.4 0.00025 21.1 0.7 4.4 4 0 0 4 4 4 2 IPT/TIG domain SKG6 PF08693.10 EGC32669.1 - 0.47 9.9 6.4 0.21 11.0 3.7 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LRR_8 PF13855.6 EGC32669.1 - 1.9 8.3 8.7 5.2 6.9 1.0 3.5 3 1 0 3 3 3 0 Leucine rich repeat Laminin_EGF PF00053.24 EGC32669.1 - 2.8 8.2 243.4 0.055 13.6 10.5 15.3 9 3 6 15 15 15 0 Laminin EGF domain Neur_chan_memb PF02932.16 EGC32670.1 - 0.0035 17.5 2.7 0.0046 17.0 2.7 1.1 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Gal4_dimer PF03902.13 EGC32670.1 - 0.021 14.9 0.4 0.083 13.1 0.1 2.1 2 0 0 2 2 2 0 Gal4-like dimerisation domain TACC_C PF05010.14 EGC32670.1 - 0.073 12.9 23.5 0.98 9.2 23.4 2.0 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal EMC3_TMCO1 PF01956.16 EGC32670.1 - 0.6 9.8 12.6 0.071 12.8 3.1 2.3 1 1 1 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SID-1_RNA_chan PF13965.6 EGC32670.1 - 3 6.1 6.1 3.8 5.8 6.1 1.4 1 1 0 1 1 1 0 dsRNA-gated channel SID-1 Bromodomain PF00439.25 EGC32671.1 - 1e-22 80.0 2.4 1.1e-22 79.8 2.4 1.0 1 0 0 1 1 1 1 Bromodomain UCH_1 PF13423.6 EGC32672.1 - 1.1e-69 235.5 25.3 4.8e-69 233.4 25.3 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.24 EGC32672.1 - 3.8e-21 76.3 0.0 1.6e-20 74.3 0.0 2.2 2 0 0 2 2 2 1 Exonuclease ANAPC4_WD40 PF12894.7 EGC32672.1 - 0.012 15.9 0.0 11 6.4 0.0 3.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain Curto_V2 PF07325.11 EGC32672.1 - 0.025 14.5 0.0 0.07 13.0 0.0 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein PSCyt2 PF07583.11 EGC32672.1 - 0.093 12.7 0.5 0.19 11.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1549) DNA_pol_A_exo1 PF01612.20 EGC32672.1 - 0.13 11.9 0.3 1.1 8.9 0.2 2.2 2 0 0 2 2 2 0 3'-5' exonuclease FERM_M PF00373.18 EGC32674.1 - 3.5e-23 82.2 0.6 7.3e-23 81.2 0.6 1.6 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 EGC32674.1 - 0.0021 18.0 0.0 0.0044 16.9 0.0 1.5 1 0 0 1 1 1 1 FERM N-terminal domain DUF2711 PF10924.8 EGC32674.1 - 0.023 14.3 0.2 0.044 13.4 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) HSF_DNA-bind PF00447.17 EGC32674.1 - 0.051 14.2 0.8 12 6.6 0.0 2.6 2 0 0 2 2 2 0 HSF-type DNA-binding zf-RING_2 PF13639.6 EGC32676.1 - 1.1e-10 41.7 10.8 1.7e-10 41.1 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC32676.1 - 1.2e-08 34.6 7.2 1.8e-08 34.1 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC32676.1 - 2e-08 34.0 11.7 3.4e-08 33.2 11.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC32676.1 - 3.1e-07 30.6 9.7 6.3e-07 29.6 9.7 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC32676.1 - 3.4e-07 30.0 11.5 6e-07 29.2 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC32676.1 - 3.2e-05 23.7 6.0 5.9e-05 22.8 6.0 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC32676.1 - 0.00024 21.0 9.3 0.0004 20.3 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC32676.1 - 0.005 16.8 6.5 0.011 15.8 6.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC32676.1 - 0.0056 16.4 10.4 0.011 15.5 10.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain TACC_C PF05010.14 EGC32676.1 - 0.0074 16.1 14.9 0.0074 16.1 14.9 2.4 1 1 1 2 2 2 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal zf-RING_10 PF16685.5 EGC32676.1 - 0.014 15.5 5.0 0.037 14.2 5.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC32676.1 - 0.024 14.8 10.6 0.06 13.5 9.3 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC32676.1 - 0.026 14.6 4.3 0.055 13.5 4.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.21 EGC32676.1 - 0.067 13.4 11.9 0.095 12.9 10.6 2.0 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain DUF1272 PF06906.11 EGC32676.1 - 0.069 13.2 7.0 0.13 12.3 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rad50_zn_hook PF04423.14 EGC32676.1 - 0.083 12.7 14.9 1.1 9.1 1.3 5.6 4 1 1 5 5 5 0 Rad50 zinc hook motif zf-RING_11 PF17123.5 EGC32676.1 - 0.089 12.6 5.6 0.19 11.5 5.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RVT PF13966.6 EGC32676.1 - 0.1 13.4 4.2 0.11 13.3 0.7 2.5 2 0 0 2 2 2 0 zinc-binding in reverse transcriptase Zn_ribbon_17 PF17120.5 EGC32676.1 - 0.6 9.8 8.5 0.99 9.1 8.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-P11 PF03854.14 EGC32676.1 - 3.4 7.4 7.1 9.2 6.0 7.1 1.7 1 1 0 1 1 1 0 P-11 zinc finger Peptidase_M1 PF01433.20 EGC32677.1 - 2.5e-73 246.3 4.8 6.7e-73 244.8 4.8 1.8 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGC32677.1 - 1.6e-53 182.3 0.0 6.4e-53 180.3 0.0 1.9 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGC32677.1 - 8.2e-49 166.3 4.8 1.5e-48 165.5 4.8 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Suppressor_P21 PF11479.8 EGC32677.1 - 0.0072 16.5 0.1 0.12 12.5 0.0 3.0 2 0 0 2 2 2 1 RNA silencing suppressor P21 C-terminal domain 4HBT PF03061.22 EGC32678.1 - 2.3e-12 47.1 0.1 4e-12 46.3 0.0 1.4 2 0 0 2 2 2 1 Thioesterase superfamily DUF4442 PF14539.6 EGC32678.1 - 0.029 14.5 0.0 0.034 14.3 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) CAP_C PF08603.11 EGC32679.1 - 6.8e-09 35.5 4.1 1.1e-08 34.9 4.1 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SEC-C PF02810.15 EGC32679.1 - 1.3e-07 31.4 8.7 2.9e-07 30.3 8.7 1.6 1 0 0 1 1 1 1 SEC-C motif TBCC PF07986.12 EGC32679.1 - 0.0013 18.5 3.6 0.0033 17.1 2.8 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor C HEAT PF02985.22 EGC32680.1 - 0.00086 19.4 0.2 7.5 7.1 0.0 4.0 3 0 0 3 3 3 2 HEAT repeat Cnd1 PF12717.7 EGC32680.1 - 0.0074 16.3 15.5 0.029 14.4 0.6 5.1 5 1 1 6 6 6 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGC32680.1 - 0.014 15.7 0.0 16 5.9 0.0 3.7 4 0 0 4 4 4 0 HEAT repeats HEAT_EZ PF13513.6 EGC32680.1 - 0.093 13.3 0.1 54 4.4 0.0 3.8 4 0 0 4 4 4 0 HEAT-like repeat Cohesin_HEAT PF12765.7 EGC32680.1 - 0.48 10.8 2.0 27 5.2 0.1 3.6 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion Tim29 PF10171.9 EGC32681.1 - 0.0023 17.5 0.1 0.078 12.5 0.0 2.3 2 1 1 3 3 3 2 Translocase of the Inner Mitochondrial membrane 29 Na_H_Exchanger PF00999.21 EGC32682.1 - 1.1e-59 202.1 54.3 1.5e-59 201.7 54.3 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DUF1180 PF06679.12 EGC32682.1 - 0.034 14.6 0.1 0.071 13.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) SLATT_5 PF18160.1 EGC32682.1 - 0.2 10.9 0.1 0.2 10.9 0.1 2.7 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 TMEM154 PF15102.6 EGC32682.1 - 0.28 11.1 8.2 1.4 8.9 0.2 3.5 3 0 0 3 3 3 0 TMEM154 protein family ETRAMP PF09716.10 EGC32682.1 - 4.3 7.5 13.8 6.7 6.8 4.4 4.2 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) ABC_tran PF00005.27 EGC32683.1 - 2.3e-54 183.6 2.8 3.2e-26 92.5 0.1 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.6 EGC32683.1 - 2e-16 60.7 12.3 5.2e-06 26.5 0.0 5.0 4 1 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system ABC_tran_Xtn PF12848.7 EGC32683.1 - 2.1e-09 37.3 1.7 2.1e-09 37.3 1.7 3.4 3 0 0 3 3 3 1 ABC transporter MMR_HSR1 PF01926.23 EGC32683.1 - 9.9e-06 25.6 0.0 0.021 14.9 0.0 3.0 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGC32683.1 - 1.2e-05 25.5 0.0 0.11 12.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGC32683.1 - 1.3e-05 24.8 3.2 0.019 14.7 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.19 EGC32683.1 - 4e-05 23.2 16.9 0.00012 21.6 1.2 4.0 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA PF00004.29 EGC32683.1 - 4.4e-05 23.9 0.1 0.093 13.2 0.0 3.1 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGC32683.1 - 0.00013 21.9 1.0 0.037 13.9 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase NB-ARC PF00931.22 EGC32683.1 - 0.00049 19.4 1.8 0.26 10.5 0.0 3.0 2 1 0 2 2 2 2 NB-ARC domain AAA_23 PF13476.6 EGC32683.1 - 0.00054 20.5 0.0 0.00054 20.5 0.0 5.2 3 1 0 3 3 2 1 AAA domain AAA_28 PF13521.6 EGC32683.1 - 0.00058 20.1 2.9 0.72 10.1 0.0 3.1 2 1 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGC32683.1 - 0.00089 19.4 1.8 2 8.7 0.1 4.0 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit RNA_helicase PF00910.22 EGC32683.1 - 0.0017 18.7 0.0 3.8 7.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase AAA_30 PF13604.6 EGC32683.1 - 0.0035 17.1 0.8 2 8.1 0.1 2.5 2 0 0 2 2 2 2 AAA domain AAA_24 PF13479.6 EGC32683.1 - 0.0066 16.2 2.6 1.1 8.9 0.1 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGC32683.1 - 0.0072 16.9 11.1 0.38 11.3 1.2 4.2 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.6 EGC32683.1 - 0.0083 16.4 3.2 0.31 11.3 0.1 3.4 2 2 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGC32683.1 - 0.015 15.4 0.0 0.015 15.4 0.0 3.5 4 0 0 4 4 3 0 Dynamin family Zeta_toxin PF06414.12 EGC32683.1 - 0.022 14.1 0.2 3.9 6.7 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin MeaB PF03308.16 EGC32683.1 - 0.028 13.4 0.3 2.8 6.8 0.1 2.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EGC32683.1 - 0.029 14.3 2.3 2.2 8.2 0.1 2.7 3 0 0 3 3 2 0 NACHT domain AbLIM_anchor PF16182.5 EGC32683.1 - 0.043 13.6 0.1 0.11 12.3 0.0 1.7 2 0 0 2 2 1 0 Putative adherens-junction anchoring region of AbLIM AAA_14 PF13173.6 EGC32683.1 - 0.064 13.3 7.4 4.7 7.3 0.1 4.2 4 2 1 5 5 5 0 AAA domain AAA_16 PF13191.6 EGC32683.1 - 0.08 13.3 5.3 0.76 10.1 0.0 2.9 2 1 0 2 2 2 0 AAA ATPase domain Cep57_MT_bd PF06657.13 EGC32683.1 - 0.081 13.4 5.1 0.26 11.7 5.1 1.8 1 0 0 1 1 1 0 Centrosome microtubule-binding domain of Cep57 TsaE PF02367.17 EGC32683.1 - 0.083 12.9 0.1 9.4 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EGC32683.1 - 0.083 12.6 0.2 3.6 7.3 0.0 2.7 3 0 0 3 3 3 0 Cytidylate kinase PRK PF00485.18 EGC32683.1 - 0.092 12.5 2.2 16 5.2 0.0 3.5 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family NTPase_1 PF03266.15 EGC32683.1 - 0.13 12.2 1.2 8.9 6.2 0.2 3.3 3 0 0 3 3 3 0 NTPase T2SSE PF00437.20 EGC32683.1 - 0.13 11.3 0.1 16 4.5 0.0 2.4 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_7 PF12775.7 EGC32683.1 - 0.51 9.8 3.3 1.7 8.1 0.0 2.8 3 0 0 3 3 3 0 P-loop containing dynein motor region Roc PF08477.13 EGC32683.1 - 0.59 10.4 5.8 15 5.8 0.0 3.6 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase DUF1940 PF09155.10 EGC32683.1 - 1.3 9.1 8.7 0.073 13.2 2.2 2.2 3 0 0 3 3 2 0 Domain of unknown function (DUF1940) Ribosomal_L3 PF00297.22 EGC32684.1 - 1e-189 630.2 12.7 1.2e-189 630.0 12.7 1.0 1 0 0 1 1 1 1 Ribosomal protein L3 DNA_pol3_beta_3 PF02768.15 EGC32684.1 - 0.033 14.0 0.7 0.095 12.5 0.4 1.8 2 0 0 2 2 2 0 DNA polymerase III beta subunit, C-terminal domain DUF4897 PF16238.5 EGC32684.1 - 0.063 13.1 0.4 0.11 12.3 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4897) tRNA_bind PF01588.20 EGC32685.1 - 8e-30 102.8 0.1 1.7e-29 101.7 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain Aurora-A_bind PF09041.10 EGC32686.1 - 0.0011 19.0 2.0 0.0011 19.0 2.0 4.1 3 1 0 3 3 3 1 Aurora-A binding DUF2838 PF10998.8 EGC32687.1 - 2e-38 131.0 11.1 2e-38 131.0 11.1 2.6 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) WD40 PF00400.32 EGC32688.1 - 4e-10 40.1 4.8 0.023 15.6 0.6 4.8 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC32688.1 - 0.0016 18.7 0.1 1 9.7 0.0 4.0 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SpoU_methylase PF00588.19 EGC32689.1 - 2.6e-29 102.2 0.1 5.7e-29 101.1 0.1 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.12 EGC32689.1 - 2.1e-05 24.7 0.5 7.5e-05 22.9 0.0 2.2 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.9 EGC32689.1 - 0.00058 19.8 0.0 0.0023 17.8 0.0 2.0 1 0 0 1 1 1 1 SAM-dependent RNA methyltransferase DUF531 PF04407.12 EGC32689.1 - 0.096 12.8 0.4 0.26 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF531) PIP5K PF01504.18 EGC32690.1 - 3.3e-76 256.1 1.8 4e-75 252.6 1.8 2.0 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Pkinase PF00069.25 EGC32691.1 - 7.6e-49 166.4 3.2 2.7e-48 164.6 0.0 3.2 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32691.1 - 3.2e-20 72.5 3.4 9.3e-15 54.6 0.0 3.6 3 1 0 3 3 3 2 Protein tyrosine kinase Kdo PF06293.14 EGC32691.1 - 0.0088 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC32691.1 - 0.026 14.4 0.0 0.14 12.1 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Alpha_kinase PF02816.18 EGC32692.1 - 7.1e-63 212.1 0.1 2.8e-62 210.1 0.1 2.1 1 0 0 1 1 1 1 Alpha-kinase family ArfGap PF01412.18 EGC32692.1 - 7.2e-20 71.2 0.0 7.2e-20 71.2 0.0 3.4 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf SUIM_assoc PF16619.5 EGC32692.1 - 0.0075 16.3 1.6 0.0075 16.3 1.6 6.2 6 2 0 6 6 6 1 Unstructured region C-term to UIM in Ataxin3 SHOCT PF09851.9 EGC32692.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Short C-terminal domain Nop14 PF04147.12 EGC32693.1 - 3.1 5.9 12.3 3.6 5.7 12.3 1.2 1 0 0 1 1 1 0 Nop14-like family AA_permease_2 PF13520.6 EGC32694.1 - 1.7e-48 165.5 24.0 2e-48 165.3 24.0 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC32694.1 - 1.5e-43 149.1 23.8 1.9e-43 148.8 23.8 1.1 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.13 EGC32694.1 - 0.0024 16.8 17.5 0.05 12.4 3.1 2.1 2 0 0 2 2 2 2 Spore germination protein Ac76 PF05814.11 EGC32694.1 - 0.64 10.1 3.7 1.7 8.7 3.7 1.6 1 0 0 1 1 1 0 Orf76 (Ac76) Pkinase PF00069.25 EGC32696.1 - 4.4e-83 278.7 0.0 5.4e-83 278.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32696.1 - 5.7e-41 140.5 0.0 7.6e-41 140.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC32696.1 - 7.1e-07 28.8 0.6 1.8e-06 27.4 0.6 1.6 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC32696.1 - 0.0011 18.3 1.7 0.54 9.5 0.1 2.9 1 1 1 2 2 2 2 Kinase-like YrbL-PhoP_reg PF10707.9 EGC32696.1 - 0.0039 16.8 1.8 0.018 14.6 1.8 1.9 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.23 EGC32696.1 - 0.014 15.3 0.0 0.064 13.2 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family PH PF00169.29 EGC32697.1 - 8.2e-13 48.8 0.3 3.1e-12 46.9 0.3 2.1 1 0 0 1 1 1 1 PH domain SAM_1 PF00536.30 EGC32697.1 - 5.2e-08 33.2 0.0 1e-07 32.3 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC32697.1 - 2e-07 31.0 0.0 7.8e-07 29.1 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_8 PF15409.6 EGC32697.1 - 5.2e-05 23.5 0.2 0.00016 21.9 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4139 PF13598.6 EGC32697.1 - 8.4e-05 22.4 0.1 0.00026 20.8 0.1 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4139) PH_11 PF15413.6 EGC32697.1 - 0.00047 20.5 8.4 0.00099 19.5 3.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH_2 PF08458.10 EGC32697.1 - 0.019 15.3 0.1 0.27 11.6 0.1 2.6 2 0 0 2 2 2 0 Plant pleckstrin homology-like region PH_16 PF17838.1 EGC32697.1 - 0.065 13.1 0.1 0.17 11.8 0.1 1.8 1 0 0 1 1 1 0 PH domain TANGO2 PF05742.12 EGC32698.1 - 2.8e-38 132.4 0.1 1.6e-36 126.6 0.1 2.1 1 1 0 1 1 1 1 Transport and Golgi organisation 2 EGF_2 PF07974.13 EGC32699.1 - 0.00074 19.8 16.3 0.00074 19.8 16.3 3.3 4 0 0 4 4 4 1 EGF-like domain DUF4448 PF14610.6 EGC32699.1 - 0.0021 17.9 0.5 0.0086 15.9 0.1 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) EGF_Tenascin PF18720.1 EGC32699.1 - 0.0083 16.1 6.2 0.0083 16.1 6.2 2.5 2 0 0 2 2 2 1 Tenascin EGF domain Laminin_EGF PF00053.24 EGC32699.1 - 0.027 14.6 23.2 0.064 13.4 9.8 2.7 2 0 0 2 2 2 0 Laminin EGF domain PBD PF00786.28 EGC32700.1 - 2.4e-17 63.0 0.2 8.2e-17 61.3 0.2 1.9 1 0 0 1 1 1 1 P21-Rho-binding domain WH2 PF02205.20 EGC32700.1 - 6.6e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 0 0 1 1 1 1 WH2 motif ketoacyl-synt PF00109.26 EGC32701.1 - 5.6e-61 206.3 0.0 8.4e-61 205.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC32701.1 - 5.7e-42 143.7 0.0 1.2e-41 142.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC32701.1 - 2.2e-39 135.9 0.0 3.8e-39 135.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC32701.1 - 5.2e-33 113.6 0.0 5.6e-32 110.2 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32701.1 - 2.4e-25 89.5 0.1 7.3e-24 84.7 0.1 2.5 2 0 0 2 2 2 1 KR domain KAsynt_C_assoc PF16197.5 EGC32701.1 - 3.8e-19 69.2 0.1 1.3e-18 67.5 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC32701.1 - 5.9e-19 68.4 0.0 9e-19 67.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC32701.1 - 6.2e-18 65.4 0.0 6.2e-18 65.4 0.0 4.9 5 0 0 5 5 3 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC32701.1 - 2.2e-09 38.5 0.0 7e-09 36.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC32701.1 - 7.2e-09 35.5 0.1 5.6e-06 26.0 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC32701.1 - 1.6e-07 30.6 4.9 4.7e-07 29.1 0.3 2.6 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family PP-binding PF00550.25 EGC32701.1 - 3.4e-06 27.3 0.0 3.6e-05 24.0 0.1 2.4 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGC32701.1 - 9.2e-06 25.5 0.0 2.6e-05 24.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EGC32701.1 - 0.00013 21.5 1.1 0.33 10.3 0.0 2.6 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EGC32701.1 - 0.00086 18.7 0.0 0.0024 17.3 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGC32701.1 - 0.0038 17.8 0.0 0.015 15.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC32701.1 - 0.0071 15.7 0.0 0.017 14.5 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGC32701.1 - 0.0077 16.1 0.0 0.02 14.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Beach PF02138.18 EGC32702.1 - 1e-123 412.1 0.5 2.3e-123 411.0 0.2 1.8 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.6 EGC32702.1 - 1.4e-20 73.2 0.0 1.4e-20 73.2 0.0 2.7 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH DUF4704 PF15787.5 EGC32702.1 - 1.3e-18 67.2 10.8 5.3e-18 65.2 6.8 3.4 2 1 0 2 2 2 1 Domain of unknown function (DUF4704) Laminin_G_3 PF13385.6 EGC32702.1 - 2.1e-11 44.2 0.1 6.7e-11 42.6 0.1 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EGC32702.1 - 4e-07 30.6 3.6 0.00093 20.0 0.3 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat PBP1_TM PF14812.6 EGC32702.1 - 0.78 10.2 4.9 2.4 8.6 4.9 1.8 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal tRNA-synt_2b PF00587.25 EGC32704.1 - 2.6e-38 131.8 0.0 4e-38 131.2 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.22 EGC32704.1 - 4.5e-17 62.3 5.5 4.5e-17 62.3 5.5 2.3 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.7 EGC32704.1 - 0.017 15.3 3.7 0.039 14.1 3.7 1.5 1 0 0 1 1 1 0 Tropomyosin like NOD PF06816.13 EGC32704.1 - 0.027 14.1 0.0 1.7 8.3 0.0 2.9 3 0 0 3 3 3 0 NOTCH protein Serine_rich PF08824.10 EGC32704.1 - 0.11 12.4 0.6 0.31 11.0 0.6 1.7 1 0 0 1 1 1 0 Serine rich protein interaction domain Cnn_1N PF07989.11 EGC32704.1 - 0.18 12.0 3.0 11 6.3 0.0 2.8 2 0 0 2 2 2 0 Centrosomin N-terminal motif 1 DUF724 PF05266.14 EGC32704.1 - 0.96 9.2 4.5 0.59 9.9 2.3 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Syntaxin PF00804.25 EGC32704.1 - 1.5 8.5 5.3 2.4 7.8 2.4 2.2 2 0 0 2 2 2 0 Syntaxin BLOC1_2 PF10046.9 EGC32704.1 - 8.4 6.8 9.9 1.8 8.9 5.1 2.4 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Pur_ac_phosph_N PF16656.5 EGC32705.1 - 6.2e-22 78.0 0.1 1.6e-21 76.7 0.1 1.7 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGC32705.1 - 7e-17 62.6 0.8 7e-17 62.6 0.8 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGC32705.1 - 3.1e-10 40.8 1.4 1.7e-09 38.4 0.2 2.6 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGC32705.1 - 0.00031 21.0 0.0 0.0021 18.3 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain GNVR PF13807.6 EGC32705.1 - 0.042 13.8 0.0 0.094 12.6 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase VMA21 PF09446.10 EGC32705.1 - 0.12 12.5 4.1 0.32 11.1 4.1 1.7 1 0 0 1 1 1 0 VMA21-like domain Interfer-bind PF09294.10 EGC32705.1 - 1 9.7 3.2 1.3 9.4 0.1 2.6 3 0 0 3 3 3 0 Interferon-alpha/beta receptor, fibronectin type III ICL PF00463.21 EGC32706.1 - 4.4e-106 355.5 0.2 1.7e-55 188.6 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.6 EGC32706.1 - 1.7e-16 60.4 0.0 2.9e-16 59.7 0.0 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase CBFD_NFYB_HMF PF00808.23 EGC32707.1 - 4e-21 75.1 1.4 4.1e-21 75.0 0.1 1.7 2 0 0 2 2 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC32707.1 - 2.3e-09 37.7 8.2 3.9e-09 37.0 8.2 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Merozoite_SPAM PF07133.11 EGC32707.1 - 0.0053 16.8 32.0 0.0081 16.2 32.0 1.2 1 0 0 1 1 1 1 Merozoite surface protein (SPAM) SDA1 PF05285.12 EGC32707.1 - 0.0085 15.6 21.8 0.0087 15.5 21.8 1.2 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EGC32707.1 - 0.015 13.6 21.0 0.014 13.7 21.0 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EGC32707.1 - 0.026 13.7 20.4 0.025 13.7 20.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.14 EGC32707.1 - 0.04 12.2 18.6 0.04 12.2 18.6 1.1 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.11 EGC32707.1 - 0.34 9.4 18.0 0.36 9.3 18.0 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Drc1-Sld2 PF11719.8 EGC32707.1 - 0.36 10.3 16.9 0.37 10.3 16.9 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein LAP1C PF05609.12 EGC32707.1 - 0.49 9.4 11.9 0.49 9.4 11.9 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Pinin_SDK_memA PF04696.13 EGC32707.1 - 1.2 9.2 15.3 1.9 8.6 15.3 1.4 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region CDC27 PF09507.10 EGC32707.1 - 1.3 8.4 20.3 1.3 8.3 20.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PI3K_1B_p101 PF10486.9 EGC32707.1 - 1.6 6.4 9.7 1.6 6.4 9.7 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit TRAP_alpha PF03896.16 EGC32707.1 - 2.2 7.4 15.4 2.8 7.1 15.4 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit YL1 PF05764.13 EGC32707.1 - 2.4 8.2 23.3 2.9 7.9 23.3 1.1 1 0 0 1 1 1 0 YL1 nuclear protein DUF2052 PF09747.9 EGC32707.1 - 3.3 7.8 23.0 4.4 7.4 23.0 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) TP53IP5 PF15331.6 EGC32707.1 - 8.5 6.5 10.6 12 6.0 10.6 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 IU_nuc_hydro PF01156.19 EGC32708.1 - 1.6e-82 277.5 0.0 1.9e-82 277.3 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase Trypan_PARP PF05887.11 EGC32710.1 - 0.00063 19.7 16.6 0.00063 19.7 16.6 3.2 3 0 0 3 3 3 1 Procyclic acidic repetitive protein (PARP) TonB_N PF16031.5 EGC32710.1 - 0.025 15.1 16.8 0.025 15.1 16.8 3.6 3 1 0 3 3 3 0 TonB polyproline region dsrm PF00035.26 EGC32711.1 - 2.4e-22 79.4 0.8 4e-10 40.3 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.16 EGC32711.1 - 2.7e-18 66.1 0.0 2.7e-18 66.1 0.0 2.6 3 0 0 3 3 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.23 EGC32711.1 - 9e-17 61.3 0.0 9e-17 61.3 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.31 EGC32711.1 - 1.3e-13 51.2 0.1 1.3e-13 51.2 0.1 3.0 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC32711.1 - 1.6e-09 37.8 0.0 3.9e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Dicer_dimer PF03368.14 EGC32711.1 - 1.3e-08 34.8 0.0 0.0011 19.1 0.1 3.0 2 0 0 2 2 2 2 Dicer dimerisation domain AAA_19 PF13245.6 EGC32711.1 - 0.00072 19.9 0.3 0.0023 18.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGC32711.1 - 0.00077 19.7 0.0 0.0031 17.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGC32711.1 - 0.018 14.5 0.0 0.036 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EGC32711.1 - 0.019 14.0 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_14 PF13173.6 EGC32711.1 - 0.077 13.0 8.0 0.097 12.7 0.3 4.4 3 1 0 3 3 3 0 AAA domain CDP-OH_P_transf PF01066.21 EGC32712.1 - 1.7e-16 60.7 0.1 1.7e-16 60.7 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DmsC PF04976.12 EGC32712.1 - 0.00041 19.9 10.4 0.00081 19.0 10.4 1.4 1 0 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) p450 PF00067.22 EGC32713.1 - 2.6e-90 303.4 0.2 2.9e-90 303.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.14 EGC32714.1 - 8.1e-25 87.2 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.7 EGC32714.1 - 1.4e-06 28.0 0.0 4.8e-06 26.2 0.0 1.8 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.12 EGC32714.1 - 0.007 16.3 0.0 0.014 15.3 0.0 1.5 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGC32714.1 - 1.3 9.0 3.5 3 7.8 3.5 1.6 1 1 0 1 1 1 0 Metallo-beta-lactamase superfamily CBM49 PF09478.10 EGC32715.1 - 0.00017 21.9 0.8 0.0012 19.1 0.8 2.3 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 Hc1 PF07432.13 EGC32715.1 - 1.6 9.1 19.1 57 4.1 20.0 2.1 2 0 0 2 2 2 0 Histone H1-like protein Hc1 2OG-FeII_Oxy_3 PF13640.6 EGC32716.1 - 9e-18 65.0 0.0 1.4e-17 64.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.6 EGC32716.1 - 6.9e-11 42.7 0.0 1.2e-10 41.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RNA_pol_Rpb2_6 PF00562.28 EGC32716.1 - 0.021 13.9 0.6 0.021 13.9 0.6 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 6 Ras PF00071.22 EGC32717.1 - 2e-30 105.5 0.0 2.5e-30 105.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32717.1 - 3.7e-10 40.1 0.0 7.8e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC32717.1 - 0.0026 17.3 0.0 0.0038 16.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC32717.1 - 0.0082 15.9 0.1 1 9.1 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGC32717.1 - 0.057 13.3 0.3 2.6 7.9 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase AAA_22 PF13401.6 EGC32717.1 - 0.078 13.2 0.0 0.43 10.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.6 EGC32717.1 - 0.17 12.3 0.0 0.22 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.22 EGC32718.1 - 2.5e-24 85.7 0.0 3.5e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC32718.1 - 0.0002 21.5 0.0 0.00086 19.5 0.0 2.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGC32718.1 - 0.18 12.0 0.3 14 5.9 0.1 2.7 2 1 1 3 3 3 0 AAA domain tRNA-synt_1 PF00133.22 EGC32719.1 - 2.2e-205 683.4 1.3 2.2e-205 683.4 1.3 2.9 2 2 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC32719.1 - 5.6e-41 140.0 0.1 5.6e-41 140.0 0.1 2.5 3 0 0 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGC32719.1 - 2.9e-16 59.2 0.9 1.4e-07 30.7 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGC32719.1 - 3.1e-05 23.6 0.0 3.1e-05 23.6 0.0 3.6 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 CAF1 PF04857.20 EGC32719.1 - 0.0047 16.1 0.4 0.0087 15.3 0.4 1.4 1 0 0 1 1 1 1 CAF1 family ribonuclease tRNA-synt_1e PF01406.19 EGC32719.1 - 0.029 13.7 0.0 0.029 13.7 0.0 3.0 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain Tim54 PF11711.8 EGC32719.1 - 0.62 8.8 10.8 1.3 7.7 10.8 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Zip PF02535.22 EGC32719.1 - 7.5 5.7 6.4 11 5.1 6.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter EB PF01683.18 EGC32720.1 - 0.0063 16.8 3.4 0.0063 16.8 3.4 7.8 1 1 5 6 6 6 3 EB module Sec1 PF00995.23 EGC32721.1 - 4e-101 340.0 19.4 4.7e-101 339.8 19.4 1.0 1 0 0 1 1 1 1 Sec1 family RabGAP-TBC PF00566.18 EGC32722.1 - 3.5e-53 180.4 1.1 3.5e-53 180.4 1.1 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain RabGAP-TBC PF00566.18 EGC32723.1 - 6.8e-59 199.1 2.2 6.8e-59 199.1 2.2 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KNOX2 PF03791.13 EGC32723.1 - 0.0015 18.0 0.1 0.0043 16.5 0.1 1.7 1 0 0 1 1 1 1 KNOX2 domain Pet20 PF08692.10 EGC32723.1 - 0.069 13.9 6.7 0.15 12.8 6.7 1.6 1 0 0 1 1 1 0 Mitochondrial protein Pet20 HTH_52 PF18576.1 EGC32723.1 - 0.12 12.6 0.2 0.3 11.3 0.2 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain ABC2_membrane_3 PF12698.7 EGC32724.1 - 0.51 9.4 4.8 0.64 9.1 4.8 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PAZ_siRNAbind PF12212.8 EGC32725.1 - 0.029 14.2 0.0 0.073 12.9 0.0 1.6 1 0 0 1 1 1 0 PAZ domain Smac_DIABLO PF09057.10 EGC32725.1 - 0.038 13.4 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Smac_DIABLO PF09057.10 EGC32726.1 - 0.017 14.5 0.5 0.02 14.3 0.5 1.1 1 0 0 1 1 1 0 Second Mitochondria-derived Activator of Caspases Folate_carrier PF01770.18 EGC32726.1 - 0.067 11.9 0.1 0.075 11.8 0.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF4834 PF16118.5 EGC32726.1 - 0.15 13.0 2.8 0.28 12.2 2.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) Pkinase PF00069.25 EGC32729.1 - 4.3e-61 206.6 0.0 8.5e-61 205.6 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32729.1 - 4.5e-46 157.2 0.1 7.1e-46 156.6 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC32729.1 - 1.2e-05 24.3 0.9 1.6e-05 23.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC32729.1 - 6.6e-05 22.0 0.1 0.00013 21.0 0.1 1.5 1 0 0 1 1 1 1 Haspin like kinase domain APH PF01636.23 EGC32729.1 - 0.0006 19.8 0.0 0.001 19.1 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGC32729.1 - 0.0013 18.4 0.1 0.005 16.4 0.1 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGC32729.1 - 0.014 14.8 0.0 0.027 13.8 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC32729.1 - 0.025 13.9 0.0 0.047 13.0 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Det1 PF09737.9 EGC32730.1 - 1.1e-116 390.3 20.1 6.9e-83 279.0 6.7 2.3 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Tn7_Tnp_TnsA_N PF08722.11 EGC32730.1 - 4.4 7.6 7.2 0.34 11.1 0.6 2.6 2 0 0 2 2 2 0 TnsA endonuclease N terminal Laminin_EGF PF00053.24 EGC32731.1 - 0.0063 16.6 28.1 0.082 13.1 6.8 3.3 3 0 0 3 3 3 2 Laminin EGF domain DUF840 PF05801.11 EGC32731.1 - 0.053 13.6 0.5 13 5.9 0.1 2.6 2 0 0 2 2 2 0 Lagovirus protein of unknown function (DUF840) Gamma-thionin PF00304.20 EGC32731.1 - 1.7 9.0 18.0 1.1 9.6 4.5 2.7 2 0 0 2 2 2 0 Gamma-thionin family EGF_2 PF07974.13 EGC32731.1 - 3.5 8.1 40.6 1.4 9.4 14.9 3.0 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 EGC32732.1 - 0.0023 18.1 37.3 0.13 12.5 8.0 3.7 2 1 1 3 3 3 3 Laminin EGF domain EGF_2 PF07974.13 EGC32732.1 - 0.089 13.2 57.9 0.077 13.4 10.1 4.0 4 0 0 4 4 4 0 EGF-like domain DUF5009 PF16401.5 EGC32733.1 - 3e-08 33.5 1.4 3e-08 33.5 1.4 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5009) DUF4500 PF14937.6 EGC32733.1 - 0.026 14.5 0.2 0.085 12.9 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) BatD PF13584.6 EGC32733.1 - 0.029 13.2 0.4 0.13 11.1 0.1 1.9 2 0 0 2 2 2 0 Oxygen tolerance MASE2 PF05230.11 EGC32733.1 - 0.075 13.1 0.0 0.075 13.1 0.0 3.6 4 0 0 4 4 4 0 MASE2 domain Fumarate_red_D PF02313.17 EGC32733.1 - 0.13 12.4 8.1 3.3 7.8 0.5 3.3 2 1 1 3 3 3 0 Fumarate reductase subunit D Baculo_11_kDa PF06143.11 EGC32733.1 - 6.2 6.5 8.2 4.7 6.9 0.1 3.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family Cyclin PF08613.11 EGC32734.1 - 3.3e-28 99.1 1.1 4e-28 98.8 1.1 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.23 EGC32734.1 - 2.4e-10 40.2 0.0 3e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain Metallophos PF00149.28 EGC32736.1 - 4.4e-12 46.9 0.6 7.5e-12 46.2 0.6 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SKG6 PF08693.10 EGC32738.1 - 0.31 10.5 5.2 0.52 9.8 5.2 1.3 1 0 0 1 1 1 0 Transmembrane alpha-helix domain IAT_beta PF11924.8 EGC32739.1 - 0.042 13.3 0.0 0.065 12.6 0.0 1.2 1 0 0 1 1 1 0 Inverse autotransporter, beta-domain TIG PF01833.24 EGC32740.1 - 7.7e-08 32.3 33.9 0.00027 21.0 1.6 6.7 6 0 0 6 6 6 4 IPT/TIG domain EGF_2 PF07974.13 EGC32740.1 - 0.00093 19.5 63.2 0.03 14.7 8.9 4.7 4 0 0 4 4 4 3 EGF-like domain DUF4448 PF14610.6 EGC32740.1 - 0.0056 16.5 3.8 0.16 11.7 0.1 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF4448) FRQ PF09421.10 EGC32740.1 - 0.075 11.1 1.0 0.11 10.5 1.0 1.1 1 0 0 1 1 1 0 Frequency clock protein LRR_8 PF13855.6 EGC32740.1 - 0.56 10.0 34.5 0.049 13.4 1.1 6.9 5 2 2 7 7 7 0 Leucine rich repeat SKG6 PF08693.10 EGC32740.1 - 2.4 7.7 10.7 0.93 9.0 0.4 2.5 2 0 0 2 2 2 0 Transmembrane alpha-helix domain VIT PF08487.10 EGC32742.1 - 6.9e-42 142.2 0.1 3e-41 140.1 0.0 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain PARP PF00644.20 EGC32742.1 - 8.5e-30 103.8 1.2 4.6e-29 101.4 1.2 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VWA_3 PF13768.6 EGC32742.1 - 8.4e-14 51.8 0.0 1.6e-13 50.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain 14-3-3 PF00244.20 EGC32742.1 - 1.3e-13 50.9 6.2 1.3e-13 50.9 6.2 2.1 3 0 0 3 3 2 1 14-3-3 protein VIT_2 PF13757.6 EGC32742.1 - 3.2e-12 46.2 0.0 7e-12 45.1 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.28 EGC32742.1 - 1.1e-10 42.0 0.0 4.8e-10 40.0 0.0 2.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Ribosomal_60s PF00428.19 EGC32742.1 - 5e-10 39.8 19.2 0.03 14.9 0.5 6.6 6 0 0 6 6 6 4 60s Acidic ribosomal protein VWA_2 PF13519.6 EGC32742.1 - 7.3e-08 33.0 0.0 1.3e-06 29.0 0.0 3.0 3 0 0 3 3 3 1 von Willebrand factor type A domain BRCT_2 PF16589.5 EGC32742.1 - 1.9e-06 28.2 0.2 6.8e-06 26.4 0.2 2.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC32742.1 - 1.5e-05 25.3 0.1 8.5e-05 22.9 0.1 2.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WH2 PF02205.20 EGC32742.1 - 0.048 13.5 0.8 0.16 11.8 0.1 2.3 2 0 0 2 2 2 0 WH2 motif RNA_pol_Rpb1_R PF05001.13 EGC32742.1 - 0.21 12.0 71.4 0.67 10.4 16.5 4.8 1 1 6 7 7 7 0 RNA polymerase Rpb1 C-terminal repeat UEV PF05743.13 EGC32743.1 - 3.1e-28 98.1 0.3 5.9e-28 97.2 0.3 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.10 EGC32743.1 - 2.6e-25 88.1 0.2 7.3e-25 86.7 0.1 1.9 2 0 0 2 2 2 1 Vps23 core domain BLOC1_2 PF10046.9 EGC32743.1 - 0.42 10.9 10.1 0.048 14.0 3.8 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlxA PF14282.6 EGC32743.1 - 0.43 10.6 26.7 0.65 10.0 5.5 2.6 2 0 0 2 2 2 0 FlxA-like protein SapB_1 PF05184.15 EGC32743.1 - 4.9 7.3 6.4 5 7.2 0.1 3.3 3 0 0 3 3 3 0 Saposin-like type B, region 1 CREPT PF16566.5 EGC32743.1 - 6.2 7.0 13.8 2.6 8.2 4.1 2.4 2 0 0 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour MCU PF04678.13 EGC32744.1 - 1.2e-45 155.7 0.5 2.1e-45 155.0 0.5 1.3 1 0 0 1 1 1 1 Mitochondrial calcium uniporter Csm1_N PF18504.1 EGC32744.1 - 2.9 8.3 7.4 3.4 8.1 1.0 3.0 3 0 0 3 3 3 0 Csm1 N-terminal domain TAP_C PF03943.13 EGC32745.1 - 1e-14 53.9 1.1 4.6e-14 51.8 0.4 2.5 3 0 0 3 3 3 1 TAP C-terminal domain LRR_9 PF14580.6 EGC32745.1 - 2.1e-06 27.4 1.2 1e-05 25.1 0.4 2.1 1 1 1 2 2 2 1 Leucine-rich repeat NTF2 PF02136.20 EGC32745.1 - 2e-05 25.1 0.0 7.1e-05 23.4 0.0 1.9 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain UBA_4 PF14555.6 EGC32745.1 - 0.0094 15.7 0.0 0.02 14.7 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain RRM_9 PF18444.1 EGC32745.1 - 0.019 14.8 0.0 0.038 13.8 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif LRR_4 PF12799.7 EGC32745.1 - 0.46 11.0 7.1 3.9 8.0 3.2 3.5 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) Ku PF02735.16 EGC32746.1 - 8.1e-63 211.8 0.1 1.7e-62 210.8 0.1 1.5 1 0 0 1 1 1 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.15 EGC32746.1 - 3.8e-46 157.6 8.4 3.8e-46 157.6 8.4 1.7 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.14 EGC32746.1 - 2.4e-11 44.2 2.2 2.4e-11 44.2 0.3 2.1 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm VWA PF00092.28 EGC32746.1 - 0.0046 17.2 1.6 0.012 15.9 0.2 2.4 2 1 1 3 3 3 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC32746.1 - 0.13 12.9 0.1 1.1 10.0 0.1 2.7 2 1 0 2 2 2 0 von Willebrand factor type A domain Transcrip_reg PF01709.20 EGC32746.1 - 0.14 11.6 2.6 0.35 10.3 2.6 1.6 1 0 0 1 1 1 0 Transcriptional regulator Ank_2 PF12796.7 EGC32747.1 - 2.6e-24 85.6 5.1 9.9e-13 48.5 0.3 4.1 1 1 3 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC32747.1 - 9.7e-22 77.1 5.0 4e-07 30.4 0.0 5.9 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC32747.1 - 9.1e-19 67.0 0.3 0.00098 19.5 0.0 5.9 4 1 1 5 5 5 5 Ankyrin repeat Ank_3 PF13606.6 EGC32747.1 - 5.6e-18 63.2 3.9 0.0021 18.4 0.0 6.9 6 1 0 6 6 6 4 Ankyrin repeat RGS PF00615.19 EGC32747.1 - 4.9e-17 62.3 4.7 2.5e-12 47.1 0.5 3.4 3 0 0 3 3 3 2 Regulator of G protein signaling domain Ank_5 PF13857.6 EGC32747.1 - 1.6e-15 57.0 12.6 1.9e-06 28.0 0.0 6.0 4 2 1 5 5 5 4 Ankyrin repeats (many copies) zf-TRAF PF02176.18 EGC32748.1 - 3.9e-12 46.7 7.8 3.9e-12 46.7 7.8 4.3 1 1 1 3 3 3 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC32748.1 - 0.0015 18.4 9.5 0.0015 18.4 9.5 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC32748.1 - 2.3 8.8 31.1 0.17 12.3 1.1 4.2 2 1 3 5 5 5 0 TRAF-like zinc-finger Sina PF03145.16 EGC32748.1 - 2.3 8.1 29.4 0.082 12.8 2.4 4.0 2 1 2 4 4 4 0 Seven in absentia protein family Mlo PF03094.15 EGC32749.1 - 0.028 12.8 3.5 0.035 12.5 3.5 1.1 1 0 0 1 1 1 0 Mlo family FAD_binding_1 PF00667.20 EGC32751.1 - 8.5e-27 94.2 2.6 1.4e-26 93.5 0.3 2.4 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.21 EGC32751.1 - 8.2e-15 55.4 0.2 4.1e-14 53.1 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGC32751.1 - 0.0022 18.1 0.3 0.0022 18.1 0.3 3.6 4 2 0 4 4 4 1 Ferric reductase NAD binding domain Peptidase_S24 PF00717.23 EGC32751.1 - 0.14 12.1 0.1 0.14 12.1 0.1 3.1 3 0 0 3 3 3 0 Peptidase S24-like Mem_trans PF03547.18 EGC32751.1 - 0.81 8.0 4.9 1.3 7.4 4.9 1.2 1 0 0 1 1 1 0 Membrane transport protein Med13_C PF06333.12 EGC32751.1 - 3.7 6.7 7.3 8 5.6 7.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal domain Presenilin PF01080.17 EGC32751.1 - 6.5 5.4 18.9 3.4 6.4 16.5 1.8 2 0 0 2 2 2 0 Presenilin Zip PF02535.22 EGC32751.1 - 9.9 5.3 14.3 15 4.7 13.7 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter FNIP PF05725.12 EGC32754.1 - 5.4e-21 74.5 30.7 1.5e-06 28.2 0.0 9.2 5 2 6 11 11 11 9 FNIP Repeat zf-B_box PF00643.24 EGC32754.1 - 3.4e-05 23.9 6.2 6.4e-05 23.0 6.2 1.4 1 0 0 1 1 1 1 B-box zinc finger Atrophin-1 PF03154.15 EGC32754.1 - 0.39 8.9 8.5 0.51 8.6 8.5 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ndc1_Nup PF09531.10 EGC32754.1 - 0.67 8.6 7.1 1.1 7.9 7.1 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Tim54 PF11711.8 EGC32754.1 - 2.1 7.0 18.7 4.6 5.9 18.7 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PHD PF00628.29 EGC32754.1 - 3 7.8 7.3 6.7 6.7 7.3 1.6 1 0 0 1 1 1 0 PHD-finger p450 PF00067.22 EGC32755.1 - 8.8e-49 166.5 0.0 9.8e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 CsgA PF17334.2 EGC32755.1 - 0.057 14.2 0.1 0.16 12.7 0.1 1.7 1 0 0 1 1 1 0 Minor curli fiber component A Ribosomal_S7 PF00177.21 EGC32758.1 - 2.3e-33 114.9 0.3 2.8e-33 114.6 0.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FNIP PF05725.12 EGC32759.1 - 3e-53 177.7 32.3 4e-16 58.9 0.5 5.7 4 2 1 5 5 5 5 FNIP Repeat DUF1769 PF08588.10 EGC32759.1 - 0.077 13.2 8.7 12 6.2 0.1 5.3 3 2 3 6 6 6 0 Protein of unknown function (DUF1769) Foie-gras_1 PF11817.8 EGC32760.1 - 7.2e-33 114.3 0.3 7.2e-33 114.3 0.3 1.6 2 0 0 2 2 2 1 Foie gras liver health family 1 Gryzun PF07919.12 EGC32760.1 - 6.8e-09 35.0 3.6 1.5e-06 27.3 0.1 2.4 2 0 0 2 2 2 2 Gryzun, putative trafficking through Golgi Gryzun-like PF12742.7 EGC32760.1 - 0.00032 20.6 0.1 0.00086 19.3 0.1 1.8 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.8 EGC32760.1 - 0.0011 18.7 0.0 0.0042 16.8 0.0 2.0 2 0 0 2 2 2 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.28 EGC32760.1 - 0.089 12.7 0.9 0.23 11.3 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat tRNA-synt_1e PF01406.19 EGC32761.1 - 7e-131 436.1 0.2 1.3e-130 435.2 0.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGC32761.1 - 4.1e-12 45.6 1.4 4.5e-05 22.4 0.2 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGC32761.1 - 0.00028 19.3 0.0 0.00028 19.3 0.0 3.1 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) tRNA-synt_1c PF00749.21 EGC32761.1 - 0.0026 16.7 0.0 0.0026 16.7 0.0 2.7 2 1 0 2 2 2 1 tRNA synthetases class I (E and Q), catalytic domain DALR_2 PF09190.11 EGC32761.1 - 0.0029 18.1 0.1 0.0029 18.1 0.1 2.5 2 0 0 2 2 2 1 DALR domain AAA PF00004.29 EGC32762.1 - 1.2e-20 74.3 0.0 2e-20 73.5 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.11 EGC32762.1 - 7.1e-17 62.0 0.2 4.5e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 BCS1 N terminal RNA_helicase PF00910.22 EGC32762.1 - 5.5e-05 23.5 0.1 0.017 15.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EGC32762.1 - 0.00024 21.1 0.0 0.00069 19.6 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGC32762.1 - 0.00042 20.2 3.3 0.0017 18.2 3.3 1.8 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGC32762.1 - 0.00064 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_16 PF13191.6 EGC32762.1 - 0.0045 17.4 0.0 0.012 16.0 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_25 PF13481.6 EGC32762.1 - 0.0092 15.6 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGC32762.1 - 0.014 15.2 0.1 0.038 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_7 PF12775.7 EGC32762.1 - 0.014 14.9 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGC32762.1 - 0.057 13.7 0.2 0.29 11.4 0.1 2.1 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC32762.1 - 0.096 13.2 1.2 0.71 10.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGC32762.1 - 0.17 12.4 1.2 0.26 11.8 0.1 1.9 2 1 0 2 2 1 0 ABC transporter UPF0560 PF10577.9 EGC32762.1 - 0.22 10.0 5.3 0.4 9.1 5.3 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 AAA_21 PF13304.6 EGC32762.1 - 0.43 10.4 4.3 0.5 10.1 0.1 3.1 4 1 1 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4746 PF15928.5 EGC32762.1 - 0.82 9.0 5.8 5.8 6.3 4.7 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) AAA_23 PF13476.6 EGC32762.1 - 9 6.7 11.9 1.8e+02 2.5 9.9 2.9 2 1 0 2 2 2 0 AAA domain NOA36 PF06524.12 EGC32762.1 - 9.3 5.5 15.1 14 4.9 15.1 1.2 1 0 0 1 1 1 0 NOA36 protein FNIP PF05725.12 EGC32763.1 - 1.8e-108 354.5 37.3 4.3e-17 62.0 0.2 8.5 5 1 5 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.13 EGC32763.1 - 0.00019 21.8 0.0 9.9 6.6 0.0 5.1 5 3 2 7 7 7 2 Phage minor tail protein Peptidase_S78 PF04586.17 EGC32763.1 - 0.0011 19.1 0.0 6 7.0 0.0 3.9 3 1 0 3 3 3 2 Caudovirus prohead serine protease Dicty_REP PF05086.12 EGC32764.1 - 0.0012 16.9 5.5 0.0012 16.9 5.5 1.8 2 0 0 2 2 2 1 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EGC32764.1 - 0.0097 14.2 6.5 0.013 13.7 6.5 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC32764.1 - 0.12 12.3 14.2 0.21 11.6 14.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2951 PF11166.8 EGC32764.1 - 1.1 9.5 4.2 0.92 9.8 1.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) PRIMA1 PF16101.5 EGC32764.1 - 7.2 6.7 7.2 4.2 7.4 0.1 3.0 3 0 0 3 3 3 0 Proline-rich membrane anchor 1 Glyco_hydro_47 PF01532.20 EGC32765.1 - 4.6e-136 454.3 0.4 7.1e-136 453.7 0.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 EGC32765.1 - 0.00042 19.7 0.1 0.58 9.4 0.0 3.7 4 0 0 4 4 4 1 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) ASC PF00858.24 EGC32765.1 - 0.0014 17.7 2.1 0.0017 17.4 2.1 1.3 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel DUF789 PF05623.12 EGC32765.1 - 0.027 14.2 0.8 0.076 12.7 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF789) Ion_trans PF00520.31 EGC32765.1 - 0.1 11.8 1.3 0.21 10.8 1.3 1.4 1 0 0 1 1 1 0 Ion transport protein EPL1 PF10513.9 EGC32765.1 - 0.39 11.1 20.0 0.91 9.9 20.0 1.6 1 0 0 1 1 1 0 Enhancer of polycomb-like Neur_chan_memb PF02932.16 EGC32765.1 - 0.97 9.4 2.4 1.6 8.8 2.4 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region HCO3_cotransp PF00955.21 EGC32765.1 - 4.3 6.1 4.7 8.2 5.1 4.7 1.4 1 0 0 1 1 1 0 HCO3- transporter family Membralin PF09746.9 EGC32765.1 - 9.4 5.2 8.1 16 4.4 8.1 1.2 1 0 0 1 1 1 0 Tumour-associated protein PUF PF00806.19 EGC32766.1 - 6.9e-58 189.2 17.8 7e-09 34.9 0.7 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf_CCCH_4 PF18345.1 EGC32766.1 - 1.3e-05 25.1 4.5 3.1e-05 23.9 4.5 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH PF00642.24 EGC32766.1 - 4.2e-05 23.3 2.8 0.00011 22.1 2.8 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Torus PF16131.5 EGC32766.1 - 0.00099 19.8 0.0 0.00099 19.8 0.0 3.1 2 0 0 2 2 2 1 Torus domain zf-CCCH_4 PF18044.1 EGC32766.1 - 0.0054 16.5 2.4 0.0054 16.5 2.4 1.8 2 0 0 2 2 2 1 CCCH-type zinc finger zf-CCCH_2 PF14608.6 EGC32766.1 - 0.011 16.2 2.2 0.029 14.8 2.2 1.7 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Macoilin PF09726.9 EGC32766.1 - 0.07 11.7 29.7 0.11 11.1 15.3 2.3 2 0 0 2 2 2 0 Macoilin family DUF374 PF04028.13 EGC32766.1 - 0.12 11.9 0.0 0.42 10.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF374) DUF3708 PF12501.8 EGC32766.1 - 0.25 11.1 5.5 0.99 9.2 5.0 2.1 1 1 1 2 2 2 0 Phosphate ATP-binding cassette transporter DUF4407 PF14362.6 EGC32766.1 - 3.4 6.9 17.1 7.1 5.9 17.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Macoilin PF09726.9 EGC32767.1 - 0.52 8.8 16.2 0.62 8.6 16.2 1.0 1 0 0 1 1 1 0 Macoilin family RTX PF02382.15 EGC32767.1 - 2.6 7.7 7.0 0.077 12.7 0.6 1.7 2 0 0 2 2 2 0 N-terminal domain in RTX protein PH PF00169.29 EGC32768.1 - 4.1e-08 33.7 0.2 4.1e-08 33.7 0.2 3.5 3 0 0 3 3 3 1 PH domain PH_11 PF15413.6 EGC32768.1 - 3e-06 27.6 0.3 3e-06 27.6 0.3 5.3 5 0 0 5 5 5 1 Pleckstrin homology domain DUF641 PF04859.12 EGC32768.1 - 0.008 16.5 2.7 0.008 16.5 2.7 18.0 3 2 15 19 19 19 3 Plant protein of unknown function (DUF641) PH_8 PF15409.6 EGC32768.1 - 0.085 13.2 9.4 0.043 14.1 1.6 3.8 3 1 0 3 3 3 0 Pleckstrin homology domain CX9C PF16860.5 EGC32769.1 - 1.1e-06 28.5 0.5 0.0046 16.9 0.2 2.1 1 1 1 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 EGC32769.1 - 0.00018 21.7 0.8 0.009 16.2 0.8 2.1 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0203) CHCH PF06747.13 EGC32769.1 - 0.00095 19.2 0.7 0.0014 18.7 0.7 1.3 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.9 EGC32769.1 - 0.021 15.0 0.5 0.053 13.8 0.5 1.7 1 1 0 1 1 1 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PRELI PF04707.14 EGC32770.1 - 4.6e-49 166.2 0.0 7.2e-49 165.6 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Fic_N PF13784.6 EGC32770.1 - 0.1 12.6 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 Fic/DOC family N-terminal Creatinase_N_2 PF16189.5 EGC32771.1 - 2.7e-55 186.9 5.7 5.4e-55 185.9 0.3 3.0 4 0 0 4 4 4 1 Creatinase/Prolidase N-terminal domain Peptidase_M24 PF00557.24 EGC32771.1 - 1.9e-39 135.5 0.2 3.2e-39 134.8 0.2 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.18 EGC32771.1 - 3.4e-30 105.4 0.0 3.2e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain Peptidase_M24_C PF16188.5 EGC32771.1 - 3e-17 62.4 1.2 7.9e-17 61.1 0.3 2.3 2 0 0 2 2 2 1 C-terminal region of peptidase_M24 FNIP PF05725.12 EGC32772.1 - 1.8e-25 88.8 63.7 6.2e-09 35.9 2.7 11.9 7 4 6 13 13 13 11 FNIP Repeat Pkinase_Tyr PF07714.17 EGC32773.1 - 4e-49 167.2 0.0 9.5e-49 166.0 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase COR PF16095.5 EGC32773.1 - 9.4e-48 162.6 0.5 2.1e-47 161.5 0.5 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Pkinase PF00069.25 EGC32773.1 - 6.6e-41 140.4 0.0 1.9e-40 138.9 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 EGC32773.1 - 9.2e-40 136.7 0.6 3.9e-39 134.7 0.1 2.3 2 0 0 2 2 2 1 RasGEF domain cNMP_binding PF00027.29 EGC32773.1 - 1.7e-23 82.5 0.1 1.4e-11 44.3 0.0 2.8 3 0 0 3 3 2 2 Cyclic nucleotide-binding domain Roc PF08477.13 EGC32773.1 - 1.9e-19 70.1 0.2 4.9e-19 68.7 0.2 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase GRAM PF02893.20 EGC32773.1 - 1.8e-14 53.6 1.6 5.7e-14 52.0 1.6 1.9 1 0 0 1 1 1 1 GRAM domain Ras PF00071.22 EGC32773.1 - 1.4e-13 50.7 0.5 3.2e-13 49.6 0.5 1.6 1 0 0 1 1 1 1 Ras family LRR_8 PF13855.6 EGC32773.1 - 6.5e-10 38.6 21.9 3.8e-06 26.6 7.9 3.9 2 1 2 4 4 4 3 Leucine rich repeat RasGEF_N PF00618.20 EGC32773.1 - 2.3e-09 37.4 0.7 1e-08 35.3 0.3 2.4 2 0 0 2 2 2 1 RasGEF N-terminal motif DEP PF00610.21 EGC32773.1 - 5.1e-09 36.1 0.0 1.4e-08 34.7 0.0 1.8 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_4 PF12799.7 EGC32773.1 - 2.1e-06 27.9 25.7 0.00038 20.8 2.5 5.8 5 0 0 5 5 5 2 Leucine Rich repeats (2 copies) APH PF01636.23 EGC32773.1 - 0.0015 18.5 0.0 0.0026 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF4854 PF16146.5 EGC32773.1 - 0.0032 17.8 0.3 0.0091 16.3 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4854) LRR_9 PF14580.6 EGC32773.1 - 0.017 14.6 6.6 0.073 12.6 6.4 2.2 1 1 0 1 1 1 0 Leucine-rich repeat AAA_18 PF13238.6 EGC32773.1 - 0.026 15.1 0.0 0.11 13.1 0.0 2.1 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGC32773.1 - 0.028 14.9 0.0 0.13 12.8 0.0 2.2 1 0 0 1 1 1 0 ABC transporter AAA_16 PF13191.6 EGC32773.1 - 0.073 13.4 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain SSP160 PF06933.11 EGC32774.1 - 0.72 8.0 17.7 0.76 7.9 17.7 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Chorion_3 PF05387.11 EGC32774.1 - 1.1 8.8 6.5 1.3 8.6 6.5 1.0 1 0 0 1 1 1 0 Chorion family 3 Cys_box PF17869.1 EGC32776.1 - 0.12 12.5 0.2 3.4 7.9 0.0 2.3 1 1 1 2 2 2 0 Anosmin cysteine rich domain EssA PF10661.9 EGC32777.1 - 0.055 13.3 1.5 0.058 13.2 0.0 1.8 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA SPX PF03105.19 EGC32777.1 - 0.43 10.5 7.0 0.45 10.4 7.0 1.1 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EGC32777.1 - 1.5 7.6 6.2 1.9 7.3 6.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain XPA_N PF01286.18 EGC32778.1 - 0.032 14.3 0.4 1.9 8.6 0.2 2.7 2 0 0 2 2 2 0 XPA protein N-terminal P-II PF00543.22 EGC32778.1 - 0.089 13.4 0.1 0.14 12.7 0.1 1.3 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II Abhydrolase_1 PF00561.20 EGC32779.1 - 1e-23 84.3 0.0 3.8e-18 66.1 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC32779.1 - 3.7e-13 49.3 0.0 2e-12 46.9 0.0 1.8 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC32779.1 - 8.1e-10 39.7 0.0 1.4e-09 38.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.14 EGC32779.1 - 3.9e-05 22.5 0.0 4.7e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 EGC32779.1 - 0.0024 17.8 0.0 0.013 15.5 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 EGC32779.1 - 0.013 14.9 0.2 0.027 13.8 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Esterase PF00756.20 EGC32779.1 - 0.018 14.7 0.0 0.018 14.7 0.0 1.3 1 1 0 1 1 1 0 Putative esterase Abhydrolase_2 PF02230.16 EGC32779.1 - 0.022 14.6 0.0 0.096 12.5 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGC32779.1 - 0.036 13.7 0.1 0.063 12.9 0.1 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Peptidase_S9 PF00326.21 EGC32779.1 - 0.041 13.4 0.3 8 5.9 0.0 2.9 2 1 0 2 2 2 0 Prolyl oligopeptidase family DUF2048 PF09752.9 EGC32779.1 - 0.061 12.4 0.1 0.26 10.4 0.1 1.8 1 1 0 1 1 1 0 Abhydrolase domain containing 18 DLH PF01738.18 EGC32779.1 - 0.081 12.5 0.0 3.7 7.0 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Thioesterase PF00975.20 EGC32779.1 - 0.13 12.3 0.0 0.21 11.7 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain Mucin PF01456.17 EGC32780.1 - 0.35 10.8 13.2 0.52 10.3 13.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGC32780.1 - 3.4 7.7 10.2 7 6.6 10.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGC32780.1 - 7.5 4.6 10.6 9.9 4.2 10.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RhoGEF PF00621.20 EGC32781.1 - 6.5e-45 153.6 4.3 6.5e-45 153.6 4.3 2.2 2 0 0 2 2 2 1 RhoGEF domain DUF2076 PF09849.9 EGC32781.1 - 0.72 9.9 6.0 0.6 10.1 4.4 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) RNA_pol_I_A49 PF06870.12 EGC32782.1 - 8.2e-42 143.4 5.4 1.1e-41 143.1 5.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor FNIP PF05725.12 EGC32783.1 - 2e-38 130.3 36.4 8.5e-10 38.6 0.1 7.5 4 2 4 8 8 8 7 FNIP Repeat Menin PF05053.13 EGC32783.1 - 7.8 4.7 13.2 13 4.0 13.2 1.3 1 0 0 1 1 1 0 Menin Presenilin PF01080.17 EGC32783.1 - 8.8 5.0 15.1 16 4.1 15.1 1.3 1 0 0 1 1 1 0 Presenilin FNIP PF05725.12 EGC32784.1 - 2.6e-87 286.8 78.4 2.7e-12 46.7 0.3 12.3 6 2 8 15 15 15 13 FNIP Repeat ThylakoidFormat PF11264.8 EGC32785.1 - 0.0028 17.4 2.0 0.0068 16.1 0.8 1.8 1 1 1 2 2 2 1 Thylakoid formation protein CDC37_C PF08564.10 EGC32785.1 - 0.053 13.6 2.7 3.8 7.7 0.3 2.2 1 1 1 2 2 2 0 Cdc37 C terminal domain Allexi_40kDa PF05549.11 EGC32785.1 - 0.07 12.6 1.7 0.078 12.5 1.7 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF4692 PF15763.5 EGC32785.1 - 0.085 13.3 1.6 0.1 13.1 1.6 1.3 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) PGAP1 PF07819.13 EGC32786.1 - 3.5e-72 242.9 0.1 1.3e-71 241.0 0.1 2.1 1 0 0 1 1 1 1 PGAP1-like protein Hydrolase_4 PF12146.8 EGC32786.1 - 0.0029 16.9 0.0 0.0052 16.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Esterase PF00756.20 EGC32786.1 - 0.0046 16.6 0.0 0.074 12.7 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Abhydrolase_6 PF12697.7 EGC32786.1 - 0.016 15.8 0.0 0.026 15.1 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.13 EGC32786.1 - 0.12 12.3 0.0 0.26 11.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold B56 PF01603.20 EGC32787.1 - 9e-160 532.2 12.3 1.2e-159 531.7 12.3 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FTCD_C PF04961.12 EGC32787.1 - 0.083 12.6 0.2 0.14 11.9 0.2 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase PseudoU_synth_2 PF00849.22 EGC32788.1 - 9.8e-25 87.5 22.4 4.7e-13 49.5 0.1 4.8 3 2 0 4 4 4 3 RNA pseudouridylate synthase S4 PF01479.25 EGC32788.1 - 0.028 14.1 0.5 0.076 12.7 0.2 1.9 2 0 0 2 2 2 0 S4 domain Pkinase PF00069.25 EGC32789.1 - 3.2e-52 177.5 0.0 5.5e-52 176.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC32789.1 - 2.6e-50 171.1 0.0 3.6e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC32789.1 - 9.6e-07 27.9 0.0 9.6e-07 27.9 0.0 2.1 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGC32789.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane PF01061.24 EGC32790.1 - 2.2e-84 282.1 55.0 1.2e-44 152.3 21.7 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC32790.1 - 8.4e-39 133.2 0.0 3.3e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGC32790.1 - 4.7e-20 71.3 3.2 6.3e-17 61.3 0.1 3.9 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC32790.1 - 7.6e-10 39.3 0.1 1.8e-09 38.1 0.1 1.5 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EGC32790.1 - 3.9e-09 36.1 59.3 7.2e-09 35.2 7.3 4.2 3 1 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGC32790.1 - 1.8e-07 31.2 0.2 2.5e-05 24.2 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC32790.1 - 7.3e-06 25.6 0.6 0.0058 16.4 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC32790.1 - 1.6e-05 24.9 0.0 0.034 14.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC32790.1 - 3.3e-05 24.4 0.1 0.026 14.9 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_18 PF13238.6 EGC32790.1 - 9.4e-05 23.0 0.0 0.83 10.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGC32790.1 - 0.0011 19.3 0.0 0.36 11.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC32790.1 - 0.0027 17.3 0.2 0.011 15.4 0.0 1.9 2 0 0 2 2 2 1 AAA domain Rad17 PF03215.15 EGC32790.1 - 0.0076 16.2 0.1 2.8 7.8 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain MMR_HSR1 PF01926.23 EGC32790.1 - 0.011 15.8 0.0 5.8 7.0 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Methyltransf_34 PF11312.8 EGC32790.1 - 0.015 14.5 0.4 0.029 13.6 0.0 1.5 2 0 0 2 2 2 0 Putative SAM-dependent methyltransferase AAA_23 PF13476.6 EGC32790.1 - 0.02 15.4 2.2 1.2 9.6 0.0 2.6 2 0 0 2 2 2 0 AAA domain cobW PF02492.19 EGC32790.1 - 0.039 13.5 0.1 0.75 9.4 0.1 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGC32790.1 - 0.059 13.1 0.3 2.6 7.7 0.4 2.3 2 0 0 2 2 2 0 AAA domain DUF3600 PF12207.8 EGC32790.1 - 0.074 13.0 0.0 1 9.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3600) Zeta_toxin PF06414.12 EGC32790.1 - 0.11 11.8 0.0 1.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_28 PF13521.6 EGC32790.1 - 0.11 12.8 0.7 1.5 9.1 0.3 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC32790.1 - 0.11 12.6 0.4 1.6 8.9 0.2 2.4 2 0 0 2 2 2 0 AAA domain BESS PF02944.20 EGC32790.1 - 0.16 11.8 0.0 0.34 10.8 0.0 1.6 1 0 0 1 1 1 0 BESS motif DUF347 PF03988.12 EGC32790.1 - 0.42 10.9 3.3 5.3 7.3 0.0 3.7 3 0 0 3 3 3 0 Repeat of Unknown Function (DUF347) Sel1 PF08238.12 EGC32791.1 - 8.9e-11 42.1 2.4 0.0025 18.4 0.1 5.0 5 0 0 5 5 5 3 Sel1 repeat TPR_1 PF00515.28 EGC32791.1 - 0.019 14.8 4.3 0.47 10.4 1.2 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TAtT PF16811.5 EGC32791.1 - 0.051 12.8 1.1 0.093 12.0 0.2 1.8 2 0 0 2 2 2 0 TRAP transporter T-component TPR_8 PF13181.6 EGC32791.1 - 0.085 13.1 6.0 1.4 9.3 1.7 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32791.1 - 2.8 8.3 11.3 0.6 10.4 0.8 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TBCC PF07986.12 EGC32792.1 - 5.9e-29 100.2 4.9 5.9e-29 100.2 4.9 2.2 2 1 0 2 2 2 1 Tubulin binding cofactor C TBCC_N PF16752.5 EGC32792.1 - 4.9e-16 59.2 14.2 4.9e-16 59.2 14.2 2.5 2 1 1 3 3 3 1 Tubulin-specific chaperone C N-terminal domain Fzo_mitofusin PF04799.13 EGC32792.1 - 0.053 13.1 11.8 0.024 14.2 8.3 2.0 1 1 1 2 2 2 0 fzo-like conserved region Spore_III_AB PF09548.10 EGC32792.1 - 2.6 8.1 9.2 4.9 7.2 9.2 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) zf-RING_4 PF14570.6 EGC32793.1 - 1.2e-19 69.8 12.5 2.3e-19 68.9 12.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_3 PF13920.6 EGC32793.1 - 1.9e-08 34.0 8.5 1.9e-08 34.0 8.5 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) RRM_1 PF00076.22 EGC32793.1 - 7.3e-08 32.1 0.0 1.5e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-RING_2 PF13639.6 EGC32793.1 - 7.9e-07 29.3 10.9 7.9e-07 29.3 10.9 1.9 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGC32793.1 - 4e-05 23.4 10.1 0.00011 22.0 10.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC32793.1 - 6e-05 22.8 9.9 0.005 16.7 4.7 2.4 1 1 1 2 2 2 2 Prokaryotic RING finger family 4 Rtf2 PF04641.12 EGC32793.1 - 8.5e-05 22.0 1.1 0.00012 21.5 1.1 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger zf-C3HC4_2 PF13923.6 EGC32793.1 - 0.00022 21.0 9.7 0.00045 20.0 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Torus PF16131.5 EGC32793.1 - 0.0041 17.8 0.1 0.0088 16.7 0.1 1.5 1 0 0 1 1 1 1 Torus domain zf-UDP PF14569.6 EGC32793.1 - 0.0044 17.1 6.7 0.0063 16.6 5.6 1.8 2 0 0 2 2 2 1 Zinc-binding RING-finger Rad50_zn_hook PF04423.14 EGC32793.1 - 0.0087 15.9 2.2 1.4 8.8 0.3 2.5 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_5 PF14634.6 EGC32793.1 - 0.013 15.5 10.2 0.028 14.4 10.2 1.6 1 0 0 1 1 1 0 zinc-RING finger domain Baculo_IE-1 PF05290.11 EGC32793.1 - 0.05 13.6 8.4 0.05 13.5 6.1 2.0 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.6 EGC32793.1 - 3.6 7.8 12.1 23 5.2 11.5 2.6 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING cNMP_binding PF00027.29 EGC32794.1 - 9.4e-26 89.7 0.0 1.6e-16 60.1 0.0 2.8 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.27 EGC32794.1 - 7e-09 36.0 0.1 7.5e-08 32.6 0.1 2.5 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC32794.1 - 3.6e-08 33.2 0.0 6.6e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Macoilin PF09726.9 EGC32794.1 - 0.3 9.6 3.4 0.43 9.1 3.4 1.1 1 0 0 1 1 1 0 Macoilin family PP2C PF00481.21 EGC32795.1 - 1.2e-49 169.2 0.3 2.5e-32 112.5 0.1 3.0 2 1 0 2 2 2 2 Protein phosphatase 2C SOG2 PF10428.9 EGC32795.1 - 0.77 8.9 20.2 0.65 9.1 4.5 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Arm PF00514.23 EGC32796.1 - 8.6e-25 86.0 26.2 0.12 12.5 0.1 17.3 18 0 0 18 18 18 6 Armadillo/beta-catenin-like repeat WW PF00397.26 EGC32796.1 - 1.7e-18 66.4 8.2 2.4e-11 43.5 0.3 2.5 2 0 0 2 2 2 2 WW domain Cnd1 PF12717.7 EGC32796.1 - 4.1e-05 23.7 32.0 0.0024 17.9 0.1 7.5 6 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 V-ATPase_H_C PF11698.8 EGC32796.1 - 0.0015 18.6 16.5 1.2 9.3 0.2 8.3 5 3 4 9 9 9 2 V-ATPase subunit H HEAT PF02985.22 EGC32796.1 - 0.0026 17.9 7.5 6 7.4 0.0 6.9 7 0 0 7 7 7 1 HEAT repeat HEAT_EZ PF13513.6 EGC32796.1 - 0.016 15.7 0.8 51 4.5 0.0 6.1 5 0 0 5 5 5 0 HEAT-like repeat APG9 PF04109.16 EGC32796.1 - 0.022 13.8 0.1 0.022 13.8 0.1 1.6 2 0 0 2 2 2 0 Autophagy protein Apg9 Atx10homo_assoc PF09759.9 EGC32796.1 - 0.042 13.9 0.2 0.042 13.9 0.2 7.4 7 1 1 8 8 8 0 Spinocerebellar ataxia type 10 protein domain FYVE PF01363.21 EGC32796.1 - 0.12 12.5 6.0 0.024 14.8 1.4 2.2 2 0 0 2 2 2 0 FYVE zinc finger 3HCDH_N PF02737.18 EGC32797.1 - 1.2e-61 207.8 5.3 1.4e-61 207.5 5.3 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.22 EGC32797.1 - 1.6e-31 108.8 0.0 3.3e-31 107.7 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_binding_2 PF03446.15 EGC32797.1 - 0.0002 21.6 0.8 0.0002 21.6 0.8 1.9 2 1 0 2 2 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGC32797.1 - 0.00031 20.4 0.1 0.00073 19.2 0.1 1.8 2 0 0 2 2 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGC32797.1 - 0.00035 20.2 0.4 0.00051 19.7 0.4 1.3 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGC32797.1 - 0.00044 19.7 0.6 0.0011 18.4 0.1 1.8 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.23 EGC32797.1 - 0.00051 20.1 0.8 0.00079 19.4 0.7 1.4 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Sacchrp_dh_NADP PF03435.18 EGC32797.1 - 0.00058 20.1 0.5 0.0012 19.1 0.4 1.6 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGC32797.1 - 0.00073 20.1 2.1 0.002 18.6 2.0 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ELFV_dehydrog PF00208.21 EGC32797.1 - 0.0023 17.7 0.6 0.0034 17.2 0.6 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase NAD_binding_7 PF13241.6 EGC32797.1 - 0.0049 17.3 0.3 0.0087 16.5 0.3 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding TrkA_N PF02254.18 EGC32797.1 - 0.0051 17.0 0.3 0.011 16.0 0.3 1.7 1 1 0 1 1 1 1 TrkA-N domain Methyltransf_31 PF13847.6 EGC32797.1 - 0.016 15.0 0.1 0.023 14.5 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain DXP_synthase_N PF13292.6 EGC32797.1 - 0.033 13.4 1.1 0.046 12.9 1.1 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase Pyr_redox_2 PF07992.14 EGC32797.1 - 0.052 12.8 0.1 0.074 12.3 0.1 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF4848 PF16140.5 EGC32797.1 - 0.057 13.0 0.1 0.087 12.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4848) Semialdhyde_dh PF01118.24 EGC32797.1 - 0.058 13.8 0.8 0.12 12.8 0.8 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Shikimate_DH PF01488.20 EGC32797.1 - 0.1 12.6 2.6 0.44 10.6 2.5 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ThiF PF00899.21 EGC32797.1 - 0.11 11.8 1.1 0.52 9.6 1.1 2.2 1 1 0 1 1 1 0 ThiF family Pyr_redox PF00070.27 EGC32797.1 - 0.11 13.0 0.2 0.25 11.9 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Ldh_1_N PF00056.23 EGC32797.1 - 0.58 10.3 6.4 10 6.2 6.4 2.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain DUF4203 PF13886.6 EGC32799.1 - 2.8e-10 40.2 28.6 3.6e-10 39.9 28.6 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) DUF3270 PF11674.8 EGC32799.1 - 1.6 9.0 7.9 5 7.4 7.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3270) BUD22 PF09073.10 EGC32800.1 - 0.53 9.6 19.1 0.96 8.7 19.1 1.3 1 0 0 1 1 1 0 BUD22 zf-C3HC4_3 PF13920.6 EGC32801.1 - 3.4e-09 36.4 7.8 5.5e-09 35.8 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC32801.1 - 8.9e-09 35.5 10.5 1.5e-08 34.8 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC32801.1 - 4.5e-08 32.8 9.5 8e-08 32.0 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC32801.1 - 2.4e-07 30.5 8.2 4e-07 29.8 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC32801.1 - 1.1e-06 28.8 6.8 2.4e-06 27.7 6.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC32801.1 - 0.00046 20.2 5.3 0.00092 19.2 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC32801.1 - 0.0032 17.4 9.6 0.0059 16.5 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC32801.1 - 0.0091 16.1 10.1 0.052 13.7 9.7 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING DZR PF12773.7 EGC32801.1 - 0.028 14.4 7.1 0.086 12.9 7.2 1.7 1 1 1 2 2 2 0 Double zinc ribbon Prok-RING_4 PF14447.6 EGC32801.1 - 0.029 14.2 8.3 0.083 12.8 8.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC32801.1 - 0.42 10.7 5.4 0.92 9.6 5.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC32801.1 - 0.46 10.7 4.2 0.84 9.8 4.2 1.4 1 0 0 1 1 1 0 zinc RING finger of MSL2 AHH PF14412.6 EGC32801.1 - 0.46 10.5 5.1 0.2 11.7 0.9 2.7 1 1 1 2 2 2 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH zf-RING_4 PF14570.6 EGC32801.1 - 0.47 10.3 11.4 3.9 7.3 11.2 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC32801.1 - 1.8 8.3 7.7 2.9 7.6 7.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RabGAP-TBC PF00566.18 EGC32803.1 - 3.5e-53 180.4 3.7 3.5e-53 180.4 3.7 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EGC32803.1 - 3.4e-11 43.6 0.0 2.5e-09 37.6 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC32803.1 - 1.8e-06 28.4 0.0 0.00019 21.9 0.0 2.8 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC32803.1 - 4.6e-05 23.6 0.0 0.00017 21.8 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC32803.1 - 5.2e-05 23.5 0.0 0.54 10.8 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGC32803.1 - 0.00058 20.1 0.0 2.1 9.2 0.0 4.1 4 0 0 4 4 4 1 Ankyrin repeat Tnp_DNA_bind PF14706.6 EGC32803.1 - 0.13 12.1 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 Transposase DNA-binding 60KD_IMP PF02096.20 EGC32803.1 - 3.5 7.5 5.5 0.66 9.9 1.1 1.9 2 0 0 2 2 2 0 60Kd inner membrane protein PSS PF03034.15 EGC32804.1 - 4.2e-112 374.4 9.8 5.1e-112 374.1 9.8 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase CNOT11 PF10155.9 EGC32805.1 - 4.4e-47 159.3 7.1 4.4e-47 159.3 7.1 2.0 2 0 0 2 2 2 1 CCR4-NOT transcription complex subunit 11 Apc15p PF05841.11 EGC32805.1 - 6.8 7.5 12.4 44 4.9 0.1 2.6 2 0 0 2 2 2 0 Apc15p protein RhoGAP PF00620.27 EGC32806.1 - 1.7e-33 115.6 2.6 7e-33 113.6 0.4 2.6 2 0 0 2 2 2 1 RhoGAP domain BAR_3 PF16746.5 EGC32806.1 - 1.2e-18 67.7 7.8 1.2e-18 67.7 7.8 1.8 2 0 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 EGC32806.1 - 9.8e-09 35.2 8.9 2.8e-08 33.7 8.9 1.7 1 1 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EGC32806.1 - 0.00037 19.7 12.6 0.00041 19.6 11.5 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GAS PF13851.6 EGC32806.1 - 0.0096 15.3 1.6 0.0096 15.3 1.6 3.0 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EGC32806.1 - 0.037 14.1 0.5 0.037 14.1 0.5 2.7 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DHR10 PF18595.1 EGC32806.1 - 7.1 6.7 11.3 2.5 8.2 3.0 2.6 2 0 0 2 2 2 0 Designed helical repeat protein 10 domain IMD PF08397.11 EGC32806.1 - 7.3 5.9 11.8 0.93 8.8 2.9 2.8 3 1 0 3 3 3 0 IRSp53/MIM homology domain Gar1 PF04410.14 EGC32807.1 - 4.5e-26 91.5 0.3 4.8e-26 91.4 0.3 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Neur_chan_memb PF02932.16 EGC32808.1 - 0.026 14.6 9.5 0.036 14.1 9.5 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region AbiTii PF18864.1 EGC32808.1 - 0.039 14.1 7.6 0.062 13.4 7.6 1.2 1 0 0 1 1 1 0 AbiTii Endostatin PF06482.11 EGC32808.1 - 2 7.8 17.9 2.7 7.4 17.9 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin SID-1_RNA_chan PF13965.6 EGC32808.1 - 2 6.7 5.8 1.9 6.8 5.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.12 EGC32808.1 - 2.3 8.0 18.5 2.7 7.7 18.5 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM70 PF14967.6 EGC32808.1 - 3.2 7.1 6.6 3.7 6.9 6.6 1.3 1 0 0 1 1 1 0 FAM70 protein SLC12 PF03522.15 EGC32808.1 - 3.6 6.5 18.2 4.1 6.3 18.2 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Hid1 PF12722.7 EGC32808.1 - 4.6 5.2 18.6 5.4 5.0 18.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Membralin PF09746.9 EGC32808.1 - 6 5.8 14.7 7.6 5.5 14.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein Serinc PF03348.15 EGC32808.1 - 7.5 5.4 8.8 9.2 5.1 8.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Y_phosphatase PF00102.27 EGC32809.1 - 2.2e-70 236.9 0.0 6.2e-70 235.4 0.0 1.7 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGC32809.1 - 4.3e-06 26.6 0.5 1.2e-05 25.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGC32809.1 - 0.00013 22.1 0.2 0.00059 20.0 0.0 2.2 2 1 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.6 EGC32809.1 - 0.0036 17.3 0.0 0.0063 16.5 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Yeast-kill-tox PF09207.11 EGC32809.1 - 0.056 14.1 0.2 3 8.5 0.1 2.5 2 0 0 2 2 2 0 Yeast killer toxin Nop14 PF04147.12 EGC32809.1 - 7.1 4.7 10.7 8.7 4.4 10.7 1.1 1 0 0 1 1 1 0 Nop14-like family SH3BGR PF04908.15 EGC32810.1 - 9.4e-13 48.2 0.3 1.4e-12 47.7 0.3 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.24 EGC32810.1 - 1.3e-11 44.5 0.0 2e-11 43.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.6 EGC32810.1 - 6e-05 23.4 0.0 7.4e-05 23.1 0.0 1.1 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ABC2_membrane PF01061.24 EGC32812.1 - 7.7e-88 293.4 59.0 3.6e-49 167.0 23.0 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC32812.1 - 4.7e-39 134.0 0.1 1.1e-18 68.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGC32812.1 - 4e-28 97.1 0.9 1.9e-23 82.2 0.0 3.8 4 0 0 4 4 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC32812.1 - 2.9e-09 37.4 0.1 9.5e-09 35.8 0.1 1.9 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGC32812.1 - 2.9e-06 27.3 0.2 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC32812.1 - 3.1e-05 23.6 0.3 0.0056 16.4 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC32812.1 - 3.4e-05 23.8 0.0 0.08 12.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC32812.1 - 0.00015 22.2 0.0 0.015 15.7 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGC32812.1 - 0.00042 19.5 19.6 0.00042 19.5 19.6 4.2 3 1 1 4 4 4 2 ABC-2 family transporter protein AAA_22 PF13401.6 EGC32812.1 - 0.0012 19.1 0.0 0.4 11.0 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC32812.1 - 0.0017 18.0 0.2 0.0048 16.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGC32812.1 - 0.0099 16.0 0.3 1.5 9.0 0.2 2.6 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC32812.1 - 0.025 15.1 0.0 0.89 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC32812.1 - 0.033 13.9 0.1 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.23 EGC32812.1 - 0.034 14.2 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGC32812.1 - 0.04 13.2 0.0 4.8 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_23 PF13476.6 EGC32812.1 - 0.074 13.5 4.7 1.2 9.6 0.0 2.8 3 0 0 3 3 2 0 AAA domain RNA_helicase PF00910.22 EGC32812.1 - 0.095 13.1 0.1 25 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EGC32812.1 - 0.11 12.2 0.1 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain BESS PF02944.20 EGC32812.1 - 0.13 12.1 0.1 0.26 11.1 0.1 1.6 1 0 0 1 1 1 0 BESS motif Rad17 PF03215.15 EGC32812.1 - 0.16 11.9 0.1 6.6 6.6 0.0 2.3 2 0 0 2 2 2 0 Rad17 P-loop domain DUF5320 PF17253.2 EGC32812.1 - 0.27 12.3 2.2 0.4 11.8 0.4 2.3 2 0 0 2 2 1 0 Family of unknown function (DUF5320) AAA_28 PF13521.6 EGC32812.1 - 2.9 8.1 4.1 1.5 9.0 0.4 2.3 2 0 0 2 2 2 0 AAA domain BRF1 PF07741.13 EGC32812.1 - 3.7 7.9 5.8 24 5.4 1.1 2.5 2 0 0 2 2 2 0 Brf1-like TBP-binding domain LRR_9 PF14580.6 EGC32813.1 - 3.7e-16 59.1 8.6 9.1e-16 57.8 8.6 1.5 1 1 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.7 EGC32813.1 - 4.6e-15 55.5 50.7 1.9e-06 28.1 10.8 3.3 2 1 3 5 5 5 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC32813.1 - 4.6e-08 32.7 17.7 7.7e-06 25.6 1.1 3.0 3 1 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.6 EGC32813.1 - 0.012 15.7 0.4 0.012 15.7 0.4 3.8 4 0 0 4 4 4 0 Leucine Rich repeat PDZ_1 PF12812.7 EGC32813.1 - 0.19 11.7 1.9 6.2 6.9 0.1 3.2 3 0 0 3 3 3 0 PDZ-like domain TbpB_C PF17483.2 EGC32813.1 - 0.22 11.9 1.7 0.52 10.7 1.7 1.7 1 1 0 1 1 1 0 C-lobe handle domain of Tf-binding protein B LRR_2 PF07723.13 EGC32813.1 - 0.63 10.8 3.1 16 6.3 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat DUF5082 PF16888.5 EGC32814.1 - 0.003 17.8 23.4 0.003 17.8 23.4 8.5 1 1 7 8 8 8 2 Domain of unknown function (DUF5082) zf-CCCH_2 PF14608.6 EGC32815.1 - 5.6e-06 26.6 7.0 0.011 16.2 2.9 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EGC32815.1 - 0.00048 20.0 5.6 0.016 15.1 3.0 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGC32815.1 - 8.8 6.3 10.2 0.2 11.5 2.8 2.2 3 0 0 3 3 3 0 CCCH-type zinc finger Sec7 PF01369.20 EGC32816.1 - 6.2e-73 244.4 1.2 9e-73 243.9 1.2 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.29 EGC32816.1 - 3.7e-26 91.7 0.3 6.1e-26 91.0 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC32816.1 - 3e-08 34.0 0.4 7.5e-08 32.7 0.4 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.6 EGC32816.1 - 8.4e-05 22.6 0.1 0.00026 21.1 0.1 1.9 1 1 0 1 1 1 1 PH domain PH_6 PF15406.6 EGC32816.1 - 0.00081 19.7 0.0 0.098 12.9 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGC32816.1 - 0.002 18.3 0.0 0.02 15.1 0.0 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain UbiA PF01040.18 EGC32817.1 - 1.8e-40 138.8 9.9 1.8e-40 138.8 9.9 1.6 1 1 1 2 2 2 1 UbiA prenyltransferase family DUF4131 PF13567.6 EGC32817.1 - 0.089 12.4 1.0 4.2 7.0 0.0 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) MOSC_N PF03476.16 EGC32818.1 - 2e-32 111.6 0.0 3.8e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.17 EGC32818.1 - 9.1e-26 90.4 0.0 1.4e-25 89.8 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Peptidase_C11 PF03415.14 EGC32818.1 - 0.057 12.8 0.0 0.075 12.4 0.0 1.3 1 0 0 1 1 1 0 Clostripain family Arf PF00025.21 EGC32819.1 - 2.4e-71 238.8 0.0 2.7e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC32819.1 - 1.3e-11 44.8 0.0 1.7e-11 44.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase G-alpha PF00503.20 EGC32819.1 - 3.4e-11 42.9 0.1 2.8e-06 26.7 0.0 2.7 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGC32819.1 - 6.9e-10 38.7 0.0 8.4e-10 38.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGC32819.1 - 2.2e-09 37.1 0.0 2.6e-09 36.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGC32819.1 - 2.2e-06 27.2 0.0 2.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC32819.1 - 0.0005 20.1 0.0 0.0023 18.0 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DLIC PF05783.11 EGC32819.1 - 0.2 10.4 0.0 0.28 9.9 0.0 1.1 1 0 0 1 1 1 0 Dynein light intermediate chain (DLIC) DUF3818 PF12825.7 EGC32820.1 - 7.8e-23 81.0 3.3 7.8e-23 81.0 3.3 4.4 3 3 0 4 4 4 1 Domain of unknown function in PX-proteins (DUF3818) CTD_bind PF04818.13 EGC32820.1 - 0.019 15.8 4.0 0.48 11.3 0.0 3.4 3 0 0 3 3 3 0 RNA polymerase II-binding domain. DUF3439 PF11921.8 EGC32820.1 - 1.3 9.0 4.8 3.1 7.8 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 7tm_3 PF00003.22 EGC32821.1 - 2.7e-22 79.7 39.3 2.7e-22 79.7 39.3 2.4 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Chlam_PMP PF02415.17 EGC32821.1 - 0.046 14.2 0.6 0.046 14.2 0.6 7.9 8 0 0 8 8 8 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat 7tm_3 PF00003.22 EGC32822.1 - 6.7e-26 91.5 35.0 6.7e-26 91.5 35.0 3.3 3 1 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR DUF4834 PF16118.5 EGC32822.1 - 0.013 16.5 8.2 0.013 16.5 8.2 6.1 5 2 1 6 6 6 0 Domain of unknown function (DUF4834) WBP-1 PF11669.8 EGC32822.1 - 0.027 15.1 2.8 10 6.8 0.6 3.4 2 0 0 2 2 2 0 WW domain-binding protein 1 CE2_N PF17996.1 EGC32823.1 - 2.6e-19 69.2 0.0 4.4e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 EGC32823.1 - 1.5e-16 61.3 0.9 7.5e-16 59.0 0.9 1.9 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGC32823.1 - 6.9e-10 39.2 0.0 1.6e-09 38.0 0.0 1.7 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SusE PF14292.6 EGC32823.1 - 0.12 12.6 0.9 0.28 11.4 0.9 1.6 1 0 0 1 1 1 0 SusE outer membrane protein FAD_binding_3 PF01494.19 EGC32824.1 - 5.4e-07 29.2 0.0 0.0026 17.1 0.0 2.3 1 1 0 2 2 2 2 FAD binding domain DUF2058 PF09831.9 EGC32824.1 - 0.1 12.8 1.9 0.24 11.6 0.4 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) DUF4125 PF13526.6 EGC32824.1 - 1.5 8.4 6.8 9.3 5.8 0.1 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4125) Meth_synt_2 PF01717.18 EGC32825.1 - 0.0054 16.1 0.0 0.3 10.3 0.0 2.5 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain Lipoprotein_6 PF01441.19 EGC32825.1 - 0.15 12.1 0.9 3 7.8 0.1 2.1 2 0 0 2 2 2 0 Lipoprotein Abhydrolase_1 PF00561.20 EGC32826.1 - 1.1e-19 71.1 0.0 1.4e-19 70.8 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC32826.1 - 1.1e-15 58.8 0.0 1.7e-15 58.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC32826.1 - 7.6e-11 41.7 0.0 1.2e-10 41.1 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 DUF676 PF05057.14 EGC32826.1 - 6.7e-06 25.8 0.0 0.079 12.5 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Ndr PF03096.14 EGC32826.1 - 0.0027 16.5 0.0 0.0046 15.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family Esterase PF00756.20 EGC32826.1 - 0.0056 16.4 0.0 0.0094 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EGC32826.1 - 0.0091 15.3 0.0 0.0091 15.3 0.0 2.6 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) LIDHydrolase PF10230.9 EGC32826.1 - 0.014 15.0 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 Lipid-droplet associated hydrolase PGAP1 PF07819.13 EGC32826.1 - 0.021 14.5 0.5 0.1 12.3 0.0 2.2 3 0 0 3 3 3 0 PGAP1-like protein Abhydrolase_5 PF12695.7 EGC32826.1 - 0.044 13.6 0.0 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.7 EGC32826.1 - 0.05 12.5 0.0 0.071 12.0 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme Palm_thioest PF02089.15 EGC32826.1 - 0.06 13.2 0.3 0.12 12.2 0.0 1.6 2 0 0 2 2 1 0 Palmitoyl protein thioesterase Ser_hydrolase PF06821.13 EGC32826.1 - 0.089 12.6 0.0 0.15 12.0 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase FNIP PF05725.12 EGC32827.1 - 1.1e-57 191.9 59.8 1.1e-10 41.5 0.7 8.1 5 1 4 9 9 9 8 FNIP Repeat LRR_6 PF13516.6 EGC32828.1 - 0.0028 17.6 0.2 0.019 15.0 0.1 6.8 7 0 0 7 7 7 4 Leucine Rich repeat Seipin PF06775.14 EGC32829.1 - 4.4e-49 167.3 2.4 7.4e-49 166.5 2.4 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) Comm PF15957.5 EGC32829.1 - 0.33 11.3 0.0 0.33 11.3 0.0 2.3 2 1 0 2 2 2 0 Commissureless NusG_II PF07009.11 EGC32829.1 - 0.97 9.7 4.7 1.1 9.4 2.5 2.3 2 0 0 2 2 2 0 NusG domain II FAD_binding_3 PF01494.19 EGC32830.1 - 7.7e-47 160.2 0.0 4.2e-30 105.2 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.18 EGC32830.1 - 0.013 15.7 0.0 0.041 14.1 0.0 1.8 1 0 0 1 1 1 0 TrkA-N domain HMMR_N PF15905.5 EGC32831.1 - 0.001 18.6 15.5 0.001 18.6 15.5 2.4 2 0 0 2 2 2 1 Hyaluronan mediated motility receptor N-terminal ROK PF00480.20 EGC32831.1 - 0.0011 18.6 0.9 0.0019 17.7 0.9 1.3 1 0 0 1 1 1 1 ROK family Exonuc_VII_L PF02601.15 EGC32831.1 - 0.4 10.2 11.7 0.18 11.3 9.1 1.6 1 1 0 1 1 1 0 Exonuclease VII, large subunit Peroxin-13_N PF04088.13 EGC32831.1 - 0.91 9.8 7.0 1.1 9.5 5.7 1.8 1 1 0 1 1 1 0 Peroxin 13, N-terminal region DUF745 PF05335.13 EGC32831.1 - 3.1 7.5 6.2 0.93 9.2 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Goodbye PF17109.5 EGC32831.1 - 4.8 7.6 12.1 0.32 11.5 1.3 3.3 2 2 0 3 3 3 0 fungal STAND N-terminal Goodbye domain Phage_lysozyme PF00959.19 EGC32831.1 - 9.2 6.8 8.1 3.4 8.2 3.7 2.3 1 1 1 2 2 2 0 Phage lysozyme R3H-assoc PF13902.6 EGC32832.1 - 1.5e-22 80.4 1.2 2.7e-22 79.6 0.3 1.9 2 0 0 2 2 2 1 R3H-associated N-terminal domain R3H PF01424.22 EGC32832.1 - 3.5e-07 30.1 0.2 8.8e-07 28.8 0.2 1.7 1 0 0 1 1 1 1 R3H domain DUF1059 PF06348.11 EGC32832.1 - 0.05 13.8 0.0 0.09 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1059) Thioredoxin PF00085.20 EGC32833.1 - 4.6e-20 71.5 0.0 5.6e-20 71.3 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EGC32833.1 - 1.6e-07 31.1 0.0 2e-07 30.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGC32833.1 - 0.00075 19.9 0.1 0.0039 17.6 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC32833.1 - 0.0013 19.0 0.0 0.0056 17.0 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like OST3_OST6 PF04756.13 EGC32833.1 - 0.011 15.1 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGC32833.1 - 0.023 14.6 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Redoxin PF08534.10 EGC32833.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Redoxin TraF PF13728.6 EGC32833.1 - 0.047 13.5 0.0 0.058 13.2 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein HD_4 PF13328.6 EGC32834.1 - 7.2e-16 58.3 0.0 9.3e-16 57.9 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.22 EGC32834.1 - 3.3e-05 24.1 0.4 5.8e-05 23.3 0.4 1.4 1 0 0 1 1 1 1 HD domain RNA_lig_T4_1 PF09511.10 EGC32834.1 - 0.038 13.8 0.6 0.078 12.8 0.5 1.4 1 1 0 1 1 1 0 RNA ligase Response_reg PF00072.24 EGC32836.1 - 5e-30 103.9 0.3 1.6e-21 76.5 0.1 2.5 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGC32836.1 - 3.4e-16 59.7 0.7 1.2e-12 48.3 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FAT PF02259.23 EGC32838.1 - 7.8e-113 377.2 1.9 1e-112 376.8 0.1 2.2 2 1 0 2 2 2 1 FAT domain PI3_PI4_kinase PF00454.27 EGC32838.1 - 4.9e-71 239.5 0.5 1.1e-70 238.3 0.5 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase DUF3385 PF11865.8 EGC32838.1 - 2.5e-64 216.1 4.0 1.7e-56 190.6 0.1 5.3 3 1 1 4 4 4 2 Domain of unknown function (DUF3385) FRB_dom PF08771.11 EGC32838.1 - 1.3e-41 141.0 0.6 1.3e-41 141.0 0.6 4.1 6 0 0 6 6 3 1 FKBP12-rapamycin binding domain HEAT_2 PF13646.6 EGC32838.1 - 2.1e-18 66.5 12.8 0.012 16.0 0.0 9.4 7 2 2 9 9 8 5 HEAT repeats FATC PF02260.20 EGC32838.1 - 2.2e-16 59.4 0.3 5.7e-16 58.0 0.3 1.8 1 0 0 1 1 1 1 FATC domain Cnd1 PF12717.7 EGC32838.1 - 6.6e-14 52.3 1.7 0.16 12.0 0.0 6.0 3 1 2 5 5 5 4 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGC32838.1 - 6.6e-14 50.8 25.1 0.03 14.6 0.0 13.0 14 0 0 14 14 12 2 HEAT repeat HEAT_EZ PF13513.6 EGC32838.1 - 5.9e-11 42.6 19.7 0.0016 18.9 0.1 10.5 12 1 1 13 13 12 4 HEAT-like repeat ParcG PF10274.9 EGC32838.1 - 6.8e-08 32.8 8.9 0.056 13.6 0.0 6.0 3 2 2 5 5 5 3 Parkin co-regulated protein Sec7_N PF12783.7 EGC32838.1 - 6.6e-07 29.4 0.3 0.22 11.4 0.0 5.0 3 1 0 3 3 3 2 Guanine nucleotide exchange factor in Golgi transport N-terminal Adaptin_N PF01602.20 EGC32838.1 - 1.3e-06 27.3 10.9 0.0013 17.3 1.3 4.6 4 2 1 5 5 5 3 Adaptin N terminal region UME PF08064.13 EGC32838.1 - 1.3e-06 28.2 2.2 3.8 7.5 0.0 7.0 6 2 1 8 8 7 2 UME (NUC010) domain Vac14_Fab1_bd PF12755.7 EGC32838.1 - 4.3e-06 27.2 2.8 18 6.0 0.0 7.0 6 2 1 7 7 7 0 Vacuolar 14 Fab1-binding region IFRD PF05004.13 EGC32838.1 - 0.0015 17.7 3.3 0.19 10.8 0.0 4.3 4 2 2 6 6 6 1 Interferon-related developmental regulator (IFRD) CLASP_N PF12348.8 EGC32838.1 - 0.0037 16.9 0.1 0.59 9.7 0.0 4.2 3 1 1 4 4 4 1 CLASP N terminal RTP1_C1 PF10363.9 EGC32838.1 - 0.021 15.0 0.0 31 4.8 0.0 5.4 2 2 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 TPR_7 PF13176.6 EGC32838.1 - 0.097 12.8 0.4 9.6 6.5 0.1 3.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32838.1 - 0.11 12.8 1.0 24 5.3 0.1 4.1 3 0 0 3 3 2 0 Tetratricopeptide repeat Dicty_CTDC PF00526.18 EGC32839.1 - 0.00011 22.0 11.6 0.00011 22.0 11.6 6.0 7 1 1 8 8 8 1 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC32839.1 - 0.018 14.9 0.0 0.038 13.8 0.0 1.5 1 0 0 1 1 1 0 PA14 domain E1-E2_ATPase PF00122.20 EGC32840.1 - 5.2e-45 153.2 0.1 5.2e-45 153.2 0.1 2.1 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGC32840.1 - 1.2e-34 120.4 0.0 1.9e-34 119.8 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGC32840.1 - 6.9e-09 36.0 0.0 2.6e-08 34.2 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain HAD PF12710.7 EGC32840.1 - 0.0036 17.7 0.0 0.0071 16.8 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC32840.1 - 0.0045 16.8 10.7 0.064 13.0 0.6 3.7 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase ComA PF02679.15 EGC32840.1 - 0.056 12.9 0.5 0.32 10.4 0.2 2.1 2 0 0 2 2 2 0 (2R)-phospho-3-sulfolactate synthase (ComA) CytB6-F_Fe-S PF08802.10 EGC32840.1 - 0.12 12.4 1.9 0.37 10.9 1.9 1.9 1 0 0 1 1 1 0 Cytochrome B6-F complex Fe-S subunit Carm_PH PF17888.1 EGC32842.1 - 0.0014 19.0 1.8 0.0032 17.8 0.6 2.3 2 0 0 2 2 2 1 Carmil pleckstrin homology domain LRR_4 PF12799.7 EGC32842.1 - 0.0027 18.1 49.4 0.012 16.1 2.6 8.0 5 1 4 9 9 9 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC32842.1 - 0.3 11.8 50.0 0.9 10.3 0.3 11.1 11 2 1 12 12 12 0 Leucine Rich Repeat LRR_6 PF13516.6 EGC32842.1 - 0.66 10.2 44.0 0.51 10.5 2.0 10.0 11 0 0 11 11 11 0 Leucine Rich repeat Metallophos PF00149.28 EGC32843.1 - 1.7e-15 58.1 1.8 2.4e-15 57.6 1.8 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FKBP_C PF00254.28 EGC32844.1 - 1.1e-29 102.6 0.0 1.3e-29 102.4 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RasGAP PF00616.19 EGC32845.1 - 1.2e-35 123.1 4.4 2.1e-26 92.9 0.9 2.6 1 1 1 2 2 2 2 GTPase-activator protein for Ras-like GTPase C2 PF00168.30 EGC32845.1 - 4.8e-16 58.9 0.0 1.1e-15 57.8 0.0 1.6 1 0 0 1 1 1 1 C2 domain Pex14_N PF04695.13 EGC32847.1 - 1.8e-33 116.4 2.5 1.8e-33 116.4 2.5 6.2 3 1 2 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF5572 PF17733.1 EGC32847.1 - 2.5e-07 30.4 1.0 2.5e-07 30.4 1.0 3.7 4 0 0 4 4 4 1 Family of unknown function (DUF5572) OmpH PF03938.14 EGC32847.1 - 0.017 15.4 7.1 0.017 15.4 7.1 3.6 3 0 0 3 3 3 0 Outer membrane protein (OmpH-like) MTABC_N PF16185.5 EGC32848.1 - 0.72 9.3 4.7 12 5.3 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial ABC-transporter N-terminal five TM region DUF5461 PF17545.2 EGC32849.1 - 2.2 8.6 10.3 5.2 7.4 0.6 3.5 3 0 0 3 3 3 0 Family of unknown function (DUF5461) G8 PF10162.9 EGC32850.1 - 0.0015 18.6 6.3 4 7.5 0.2 4.0 2 2 1 3 3 3 3 G8 domain AIDA PF16168.5 EGC32850.1 - 0.026 14.6 0.4 0.11 12.6 0.4 2.1 1 0 0 1 1 1 0 Adhesin of bacterial autotransporter system, probable stalk Amnionless PF14828.6 EGC32850.1 - 0.037 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 Amnionless ECH_1 PF00378.20 EGC32852.1 - 1.7e-49 168.4 0.2 2.5e-49 167.9 0.2 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC32852.1 - 8e-25 88.0 0.1 1.8e-24 86.8 0.1 1.4 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase BRE1 PF08647.11 EGC32852.1 - 0.028 14.5 0.4 0.057 13.5 0.4 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Rad51 PF08423.11 EGC32854.1 - 2e-45 155.1 0.0 2.5e-45 154.7 0.0 1.1 1 0 0 1 1 1 1 Rad51 ATPase PF06745.13 EGC32854.1 - 6.2e-08 32.3 0.0 9.4e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 KaiC AAA_25 PF13481.6 EGC32854.1 - 1.2e-07 31.5 0.0 2.2e-07 30.7 0.0 1.3 1 1 0 1 1 1 1 AAA domain RecA PF00154.21 EGC32854.1 - 0.0022 17.5 0.2 0.9 8.9 0.1 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein AAA_24 PF13479.6 EGC32854.1 - 0.021 14.6 0.0 0.12 12.1 0.0 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGC32854.1 - 0.097 12.8 0.0 0.19 11.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGC32854.1 - 0.13 12.7 0.0 1.3 9.5 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PUF PF00806.19 EGC32854.1 - 0.22 11.3 1.8 1.5 8.7 0.8 2.8 2 1 0 2 2 2 0 Pumilio-family RNA binding repeat RhoGEF PF00621.20 EGC32855.1 - 7.3e-36 124.1 1.9 7.3e-36 124.1 1.9 3.4 3 1 0 3 3 3 2 RhoGEF domain zinc_ribbon_2 PF13240.6 EGC32855.1 - 7.4e-05 22.3 5.3 0.00018 21.1 5.3 1.7 1 0 0 1 1 1 1 zinc-ribbon domain zf-ribbon_3 PF13248.6 EGC32855.1 - 0.0014 17.9 4.4 0.0039 16.6 4.4 1.7 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.7 EGC32855.1 - 0.0018 18.2 0.8 0.0048 16.9 0.8 1.6 1 0 0 1 1 1 1 Double zinc ribbon NOB1_Zn_bind PF08772.11 EGC32855.1 - 0.037 14.2 0.6 0.15 12.2 0.6 2.1 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like zf-tcix PF14952.6 EGC32855.1 - 1.7 8.3 5.7 4.3 7.0 5.7 1.7 1 0 0 1 1 1 0 Putative treble-clef, zinc-finger, Zn-binding zinc_ribbon_15 PF17032.5 EGC32855.1 - 1.8 9.4 5.9 5.9 7.7 4.0 3.1 2 0 0 2 2 2 0 zinc-ribbon family DUF3584 PF12128.8 EGC32855.1 - 2.3 5.6 50.9 0.12 9.8 39.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF4588 PF15251.6 EGC32856.1 - 0.0055 16.5 11.0 0.012 15.4 10.9 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF4588) RIFIN PF02009.16 EGC32856.1 - 0.39 10.6 5.5 0.59 10.0 5.5 1.2 1 0 0 1 1 1 0 Rifin Peptidase_C1 PF00112.23 EGC32857.1 - 1.3e-84 283.7 4.2 1.8e-84 283.2 4.2 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC32857.1 - 1.3e-15 57.5 2.4 2.6e-15 56.6 2.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC32857.1 - 0.0033 16.3 2.8 0.17 10.6 0.0 2.4 2 1 0 2 2 2 2 Peptidase C1-like family MecA_N PF05223.11 EGC32857.1 - 0.067 13.5 0.6 1.7 8.9 0.1 2.3 1 1 1 2 2 2 0 NTF2-like N-terminal transpeptidase domain Peptidase_C1 PF00112.23 EGC32858.1 - 6.9e-80 268.2 5.7 6.9e-80 268.2 5.7 1.3 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC32858.1 - 1.2e-15 57.6 7.7 2.2e-15 56.8 7.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC32858.1 - 0.22 10.3 4.9 1.1 8.0 0.1 2.5 3 0 0 3 3 3 0 Peptidase C1-like family AntA PF08346.12 EGC32858.1 - 0.83 10.3 3.7 47 4.6 2.9 2.9 2 1 0 2 2 2 0 AntA/AntB antirepressor Peptidase_C1 PF00112.23 EGC32859.1 - 1.6e-83 280.1 7.1 2.8e-83 279.3 7.1 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC32859.1 - 1.2e-16 60.9 8.5 2.3e-16 59.9 8.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC32859.1 - 0.0027 16.6 2.8 0.093 11.5 0.1 2.3 2 1 0 2 2 2 2 Peptidase C1-like family zf-C2H2_2 PF12756.7 EGC32860.1 - 1.1e-38 131.6 26.3 7.4e-18 64.8 3.2 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.8 EGC32860.1 - 0.00013 22.2 3.3 0.00013 22.2 3.3 4.1 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.26 EGC32860.1 - 0.025 15.0 1.3 0.025 15.0 1.3 5.2 5 0 0 5 5 5 0 Zinc finger, C2H2 type zf-BED PF02892.15 EGC32860.1 - 0.034 14.2 18.4 0.29 11.2 0.4 5.1 5 0 0 5 5 5 0 BED zinc finger zf-C2H2_4 PF13894.6 EGC32860.1 - 0.053 14.4 31.7 0.47 11.4 0.4 5.6 5 0 0 5 5 5 0 C2H2-type zinc finger CpXC PF14353.6 EGC32860.1 - 0.063 13.3 2.2 2.4 8.2 0.1 3.1 3 0 0 3 3 3 0 CpXC protein LAM_C PF12544.8 EGC32860.1 - 0.13 12.4 0.2 0.53 10.5 0.2 2.1 1 0 0 1 1 1 0 Lysine-2,3-aminomutase PyrI_C PF02748.15 EGC32860.1 - 0.31 11.0 11.0 1.3 9.0 0.1 4.6 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain NYD-SP28 PF14772.6 EGC32860.1 - 4.5 7.4 8.0 0.28 11.2 0.5 2.8 3 0 0 3 3 3 0 Sperm tail HNH_5 PF14279.6 EGC32860.1 - 5.9 6.8 11.9 0.78 9.6 0.2 3.9 4 0 0 4 4 4 0 HNH endonuclease LMBR1 PF04791.16 EGC32861.1 - 3.9e-133 445.1 32.0 4.8e-133 444.8 32.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein DUF3040 PF11239.8 EGC32861.1 - 0.24 11.7 1.2 1.3 9.4 1.2 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3040) Acyl_transf_1 PF00698.21 EGC32862.1 - 4.3e-15 56.0 0.0 5.4e-15 55.7 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain PLDc PF00614.22 EGC32863.1 - 9.5e-09 35.1 0.1 0.0039 17.3 0.2 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGC32863.1 - 2.2e-08 34.1 0.4 0.00029 20.7 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain EOS1 PF12326.8 EGC32863.1 - 0.048 13.6 1.0 9.1 6.2 0.1 2.9 3 0 0 3 3 3 0 N-glycosylation protein Presenilin PF01080.17 EGC32863.1 - 0.061 12.1 4.6 0.092 11.5 4.6 1.2 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC32863.1 - 0.072 13.1 16.7 0.1 12.5 16.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TMEM51 PF15345.6 EGC32863.1 - 1.1 9.1 6.8 2.1 8.1 0.7 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 CPSF100_C PF13299.6 EGC32863.1 - 3.8 7.7 6.3 2.2 8.4 0.4 2.2 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal RP-C_C PF11800.8 EGC32863.1 - 6.5 6.8 7.3 4.3 7.4 0.6 2.2 2 0 0 2 2 2 0 Replication protein C C-terminal region Rxt3 PF08642.10 EGC32863.1 - 8.6 7.2 6.9 23 5.7 1.3 2.3 2 0 0 2 2 2 0 Histone deacetylation protein Rxt3 PLDc PF00614.22 EGC32864.1 - 3e-08 33.5 0.1 0.0071 16.5 0.2 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGC32864.1 - 7.5e-06 25.9 0.9 0.00062 19.7 0.0 3.0 2 0 0 2 2 2 1 PLD-like domain TFIIA PF03153.13 EGC32864.1 - 0.012 15.7 38.6 0.11 12.5 15.4 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGC32864.1 - 1.1 7.9 22.2 0.26 10.0 4.8 2.4 2 0 0 2 2 2 0 Presenilin AAA_16 PF13191.6 EGC32865.1 - 6.9e-29 101.4 0.0 2.2e-28 99.8 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain Response_reg PF00072.24 EGC32865.1 - 1.2e-25 89.9 0.5 5e-25 87.8 0.2 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.26 EGC32865.1 - 2.9e-24 85.7 0.6 9.3e-24 84.1 0.6 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.25 EGC32865.1 - 5.7e-19 68.5 0.3 5.6e-08 32.5 0.1 3.2 3 0 0 3 3 3 2 Protein kinase domain HisKA PF00512.25 EGC32865.1 - 5.5e-16 58.4 0.1 1.4e-15 57.0 0.1 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase_Tyr PF07714.17 EGC32865.1 - 1.8e-12 47.1 0.0 1.6e-06 27.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase GAF PF01590.26 EGC32865.1 - 2.9e-07 31.2 0.0 2.5e-06 28.2 0.0 2.4 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.6 EGC32865.1 - 5.8e-06 26.7 0.0 1.7e-05 25.1 0.0 1.8 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.6 EGC32865.1 - 0.0022 18.3 5.8 0.016 15.5 5.4 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32865.1 - 0.0028 17.4 0.5 0.013 15.3 0.3 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32865.1 - 0.66 10.2 10.4 0.036 14.2 0.4 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGC32865.1 - 2.2 8.4 5.0 0.52 10.4 1.0 2.1 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGC32865.1 - 3.8 7.9 6.7 0.96 9.8 0.2 3.2 3 0 0 3 3 2 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.15 EGC32866.1 - 1.7e-183 610.9 0.0 2.2e-183 610.6 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.21 EGC32866.1 - 5.5e-21 74.4 0.0 1.4e-20 73.0 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.16 EGC32866.1 - 3.1e-17 62.9 0.1 9.3e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 ATP cone domain ParB PF08775.10 EGC32866.1 - 0.087 13.3 1.4 0.27 11.7 0.1 2.2 2 0 0 2 2 2 0 ParB family DUF382 PF04037.13 EGC32867.1 - 7.8e-53 178.0 0.2 7.8e-53 178.0 0.2 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF382) PSP PF04046.16 EGC32867.1 - 4.3e-21 74.5 4.3 7.6e-21 73.7 4.3 1.4 1 0 0 1 1 1 1 PSP ThrE PF06738.12 EGC32868.1 - 9.5e-64 215.0 28.6 3e-55 187.2 8.2 2.2 2 0 0 2 2 2 2 Putative threonine/serine exporter ThrE_2 PF12821.7 EGC32868.1 - 1e-13 51.5 36.4 4.5e-12 46.2 11.0 2.4 2 0 0 2 2 2 2 Threonine/Serine exporter, ThrE zf-C3H1 PF10650.9 EGC32869.1 - 8.7e-11 41.3 3.0 1.5e-10 40.6 3.0 1.4 1 0 0 1 1 1 1 Putative zinc-finger domain Drf_FH1 PF06346.12 EGC32871.1 - 1.3e-05 25.0 4.7 2.8e-05 23.9 4.7 1.5 1 0 0 1 1 1 1 Formin Homology Region 1 TP_methylase PF00590.20 EGC32872.1 - 9.4e-19 68.2 0.0 2e-18 67.1 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_hydro_63 PF03200.16 EGC32873.1 - 8.4e-10 38.0 12.0 1.8e-08 33.6 3.3 4.3 3 1 0 3 3 3 2 Glycosyl hydrolase family 63 C-terminal domain CS PF04969.16 EGC32874.1 - 5.6e-05 24.1 0.0 6.8e-05 23.8 0.0 1.1 1 0 0 1 1 1 1 CS domain Exo84_C PF16528.5 EGC32875.1 - 6.2e-38 130.7 1.8 6.2e-38 130.7 1.8 1.8 2 0 0 2 2 2 1 Exocyst component 84 C-terminal Vps51 PF08700.11 EGC32875.1 - 1.6e-06 28.1 0.3 5.8e-06 26.3 0.1 2.1 2 0 0 2 2 2 1 Vps51/Vps67 Sec5 PF15469.6 EGC32875.1 - 0.0024 17.7 2.4 0.0024 17.7 2.4 2.6 3 0 0 3 3 3 1 Exocyst complex component Sec5 ALC PF17527.2 EGC32875.1 - 0.034 13.8 0.4 0.088 12.4 0.4 1.7 1 0 0 1 1 1 0 Phage ALC protein T6_Ig_like PF18002.1 EGC32875.1 - 0.084 12.7 0.1 0.23 11.3 0.1 1.7 1 0 0 1 1 1 0 T6 antigen Ig like domain RNA_pol_A_bac PF01000.26 EGC32876.1 - 4.8e-36 123.5 0.3 1.3e-35 122.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.24 EGC32876.1 - 7.4e-23 79.8 0.0 1e-22 79.3 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain GATase PF00117.28 EGC32877.1 - 5.4e-11 42.6 0.8 5.4e-10 39.4 0.8 2.0 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGC32877.1 - 0.0046 16.6 0.0 0.007 16.0 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EGC32877.1 - 0.0092 15.7 0.6 0.018 14.8 0.6 1.6 1 1 0 1 1 1 1 Peptidase C26 Ank_2 PF12796.7 EGC32878.1 - 1.6e-18 67.0 1.9 1.7e-08 34.9 0.4 3.5 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC32878.1 - 6.8e-12 44.5 0.3 0.062 13.9 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.6 EGC32878.1 - 8.4e-11 42.2 3.5 0.01 16.4 0.2 4.7 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC32878.1 - 3.5e-09 36.7 3.2 0.00017 21.8 0.2 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC32878.1 - 8e-08 32.4 1.1 0.51 10.9 0.2 4.6 4 0 0 4 4 4 2 Ankyrin repeat zf-C3HC4_3 PF13920.6 EGC32878.1 - 4.7e-05 23.2 12.6 4.7e-05 23.2 12.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.8 EGC32878.1 - 9.8e-05 22.3 6.2 0.0003 20.7 6.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC32878.1 - 0.0099 15.9 13.4 0.0099 15.9 13.4 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Acetyltransf_7 PF13508.7 EGC32879.1 - 3.5e-10 40.2 0.0 5.1e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC32879.1 - 1.3e-09 38.3 0.0 1.8e-09 37.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.7 EGC32879.1 - 1.1e-08 35.1 0.0 1.8e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC32879.1 - 1.5e-07 31.4 0.0 2.5e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC32879.1 - 0.0011 18.5 0.2 0.0012 18.3 0.2 1.3 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGC32879.1 - 0.012 15.7 0.0 0.019 15.1 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGC32879.1 - 0.077 13.0 0.0 0.14 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.24 EGC32880.1 - 2.6e-155 517.8 9.3 3e-155 517.6 9.3 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF956 PF06115.11 EGC32880.1 - 0.046 13.4 0.2 1 9.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF956) PucR PF07905.11 EGC32880.1 - 0.1 12.9 0.0 0.27 11.5 0.0 1.7 1 1 0 1 1 1 0 Purine catabolism regulatory protein-like family Vps55 PF04133.14 EGC32882.1 - 7.8e-38 129.0 7.0 8.8e-38 128.9 7.0 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 DENN PF02141.21 EGC32883.1 - 3.2e-53 180.5 5.0 8.3e-53 179.1 5.0 1.8 1 0 0 1 1 1 1 DENN (AEX-3) domain WD40 PF00400.32 EGC32883.1 - 1.7e-36 123.6 38.2 8.3e-07 29.6 0.3 9.4 9 0 0 9 9 9 7 WD domain, G-beta repeat uDENN PF03456.18 EGC32883.1 - 1.7e-13 51.1 0.4 1.7e-13 51.1 0.4 2.5 2 0 0 2 2 2 1 uDENN domain C2 PF00168.30 EGC32883.1 - 3e-10 40.3 1.1 1.2e-09 38.3 1.1 2.1 1 0 0 1 1 1 1 C2 domain SBF2 PF12335.8 EGC32883.1 - 4.1e-09 36.4 0.5 4.1e-09 36.4 0.5 3.8 4 0 0 4 4 4 1 Myotubularin protein WD40_like PF17005.5 EGC32883.1 - 1.5e-07 31.1 8.1 0.0072 15.7 0.1 4.6 3 1 1 4 4 4 3 WD40-like domain dDENN PF03455.19 EGC32883.1 - 8.7e-07 28.8 1.2 4.1e-06 26.7 0.8 2.5 2 0 0 2 2 2 1 dDENN domain ANAPC4_WD40 PF12894.7 EGC32883.1 - 0.0066 16.7 5.4 14 6.1 0.1 5.4 2 1 4 6 6 6 1 Anaphase-promoting complex subunit 4 WD40 domain DUF3591 PF12157.8 EGC32884.1 - 1.8e-151 504.8 0.0 1.8e-151 504.8 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3591) Bromodomain PF00439.25 EGC32884.1 - 2.7e-16 59.4 1.1 1.1e-15 57.4 1.1 2.1 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.11 EGC32884.1 - 1.9e-05 24.8 2.8 3.5e-05 24.0 1.4 2.2 2 0 0 2 2 2 1 TATA box-binding protein binding Opi1 PF08618.10 EGC32885.1 - 1.4 8.1 7.6 2.9 7.0 7.6 1.5 1 0 0 1 1 1 0 Transcription factor Opi1 GATA PF00320.27 EGC32886.1 - 3.2e-06 26.7 0.8 3.2e-06 26.7 0.8 2.2 2 2 0 2 2 2 1 GATA zinc finger Dicty_REP PF05086.12 EGC32886.1 - 0.48 8.3 10.8 0.67 7.9 10.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Tir_receptor_C PF07489.11 EGC32886.1 - 0.87 9.5 8.1 1.1 9.1 8.1 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus BNIP2 PF12496.8 EGC32886.1 - 4 7.9 8.7 6.4 7.2 8.7 1.5 1 1 0 1 1 1 0 Bcl2-/adenovirus E1B nineteen kDa-interacting protein 2 SprA-related PF12118.8 EGC32886.1 - 6.8 5.7 8.3 0.48 9.5 3.9 1.3 2 0 0 2 2 2 0 SprA-related family ALMT PF11744.8 EGC32887.1 - 2e-11 43.4 14.6 2e-11 43.4 14.6 2.6 3 0 0 3 3 3 1 Aluminium activated malate transporter FUSC_2 PF13515.6 EGC32887.1 - 1.1e-10 41.7 16.0 1.1e-10 41.7 16.0 2.9 2 1 1 3 3 3 1 Fusaric acid resistance protein-like Peptidase_C1 PF00112.23 EGC32888.1 - 9.8e-60 202.3 7.5 1.2e-59 202.1 7.5 1.0 1 0 0 1 1 1 1 Papain family cysteine protease PAN_3 PF08277.12 EGC32888.1 - 0.071 12.9 2.2 0.14 12.0 1.0 2.1 2 0 0 2 2 2 0 PAN-like domain Peptidase_C1_2 PF03051.15 EGC32888.1 - 0.12 11.1 2.9 5 5.8 0.1 2.7 3 0 0 3 3 3 0 Peptidase C1-like family CAMSAP_CKK PF08683.11 EGC32888.1 - 0.17 12.0 0.1 0.3 11.3 0.1 1.3 1 0 0 1 1 1 0 Microtubule-binding calmodulin-regulated spectrin-associated MtN3_slv PF03083.16 EGC32889.1 - 2.1e-28 98.2 15.7 4.9e-15 55.3 4.9 2.4 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange LAB_N PF07578.11 EGC32889.1 - 0.063 13.4 7.8 1.5 9.0 0.4 3.4 2 1 1 3 3 3 0 Lipid A Biosynthesis N-terminal domain MPC PF03650.13 EGC32889.1 - 0.073 13.2 1.3 11 6.3 0.1 2.4 1 1 2 3 3 3 0 Mitochondrial pyruvate carriers PseudoU_synth_2 PF00849.22 EGC32890.1 - 4.7e-27 95.0 11.2 8.5e-14 51.9 0.0 3.8 2 2 1 3 3 3 2 RNA pseudouridylate synthase MDM10 PF12519.8 EGC32890.1 - 1.6 7.5 17.0 7.3 5.3 12.7 2.3 2 0 0 2 2 2 0 Mitochondrial distribution and morphology protein 10 XRN_M PF17846.1 EGC32890.1 - 8.2 5.3 21.8 3.1 6.6 1.6 2.4 2 0 0 2 2 2 0 Xrn1 helical domain MAJIN PF15077.6 EGC32890.1 - 8.8 6.0 19.4 7.9 6.2 1.9 2.3 2 0 0 2 2 2 0 Membrane-anchored junction protein Pkinase_Tyr PF07714.17 EGC32892.1 - 3.4e-58 197.0 0.0 5.2e-58 196.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC32892.1 - 1.1e-46 159.4 0.0 1.9e-46 158.6 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGC32892.1 - 2e-29 102.8 0.1 5e-29 101.5 0.1 1.7 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 EGC32892.1 - 4.8e-06 26.8 0.0 1.5e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase ketoacyl-synt PF00109.26 EGC32893.1 - 2.1e-63 214.2 0.0 3.8e-63 213.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32893.1 - 6.4e-38 131.0 0.0 1e-37 130.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC32893.1 - 8.9e-35 119.3 0.0 1.1e-33 115.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC32893.1 - 3.6e-24 85.6 0.0 9.9e-24 84.2 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC32893.1 - 2e-19 70.2 0.0 2e-19 70.2 0.0 3.6 4 0 0 4 4 3 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC32893.1 - 1.7e-14 54.2 0.9 4.5e-14 52.9 0.2 2.1 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC32893.1 - 8.5e-10 39.8 0.0 1.3e-08 35.9 0.0 2.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PS-DH PF14765.6 EGC32893.1 - 7.3e-09 35.3 0.0 8.6e-05 21.9 0.0 2.2 1 1 0 2 2 2 2 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGC32893.1 - 1.2e-05 24.9 0.0 3.3e-05 23.4 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 EGC32893.1 - 1.7e-05 24.6 0.0 4.4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC32893.1 - 3.5e-05 24.4 0.0 0.00018 22.1 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC32893.1 - 4e-05 23.5 0.0 0.00011 22.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC32893.1 - 8.2e-05 22.9 0.1 0.0002 21.6 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF1430 PF07242.11 EGC32893.1 - 0.0041 17.4 0.4 0.026 14.8 0.4 2.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1430) GDP_Man_Dehyd PF16363.5 EGC32893.1 - 0.0071 15.8 0.2 0.016 14.6 0.2 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Methyltransf_31 PF13847.6 EGC32893.1 - 0.0073 16.1 6.7 0.086 12.6 0.0 4.7 5 0 0 5 5 5 1 Methyltransferase domain Mito_carr PF00153.27 EGC32894.1 - 1.5e-60 201.1 1.8 1.5e-19 69.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.19 EGC32894.1 - 0.043 14.2 0.2 0.26 11.7 0.3 2.2 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.7 EGC32895.1 - 5.3e-27 94.2 6.1 4.9e-10 39.9 0.1 6.7 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC32895.1 - 8.9e-19 67.6 10.9 1.2e-06 28.9 0.1 7.4 5 2 1 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC32895.1 - 5.7e-18 64.5 3.4 0.0015 18.9 0.0 7.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.6 EGC32895.1 - 3.2e-12 46.4 19.7 6.2e-08 32.8 0.0 6.8 6 1 2 8 8 8 5 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC32895.1 - 2.3e-10 39.8 4.7 0.0041 17.5 0.0 7.7 9 0 0 9 9 9 2 Ankyrin repeat F-box-like PF12937.7 EGC32895.1 - 1e-08 34.9 0.1 2.5e-08 33.7 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC32895.1 - 2e-07 30.7 1.9 2e-07 30.7 1.9 2.5 2 0 0 2 2 2 1 F-box domain zf-TRAF_2 PF15965.5 EGC32895.1 - 0.0017 18.8 4.5 0.0017 18.8 4.5 2.8 2 0 0 2 2 2 1 TRAF-like zinc-finger Lip_prot_lig_C PF10437.9 EGC32895.1 - 0.027 14.5 1.4 2.8 8.0 0.2 3.1 2 0 0 2 2 2 0 Bacterial lipoate protein ligase C-terminus PH PF00169.29 EGC32896.1 - 1.1e-07 32.3 0.0 2.4e-07 31.2 0.0 1.5 1 0 0 1 1 1 1 PH domain Sec63 PF02889.16 EGC32897.1 - 1.1e-22 80.5 0.6 4e-14 52.4 1.5 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.31 EGC32897.1 - 2.8e-17 62.6 2.4 4.5e-17 61.9 0.7 2.4 2 0 0 2 2 2 1 DnaJ domain S10_plectin PF03501.15 EGC32898.1 - 8.9e-39 131.5 0.4 1.1e-38 131.2 0.4 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Ctr PF04145.15 EGC32900.1 - 4.7e-23 82.4 13.7 4e-21 76.2 13.7 2.0 1 1 0 1 1 1 1 Ctr copper transporter family PDR_CDR PF06422.12 EGC32900.1 - 0.6 10.0 3.4 0.34 10.8 1.0 1.8 2 0 0 2 2 2 0 CDR ABC transporter CBFD_NFYB_HMF PF00808.23 EGC32902.1 - 1.5e-19 70.0 0.0 1.8e-19 69.8 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC32902.1 - 2.5e-11 44.0 0.0 3e-11 43.8 0.0 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mpv17_PMP22 PF04117.12 EGC32903.1 - 5.7e-17 61.7 0.1 1.2e-16 60.7 0.1 1.5 1 0 0 1 1 1 1 Mpv17 / PMP22 family EamA PF00892.20 EGC32903.1 - 0.0017 18.6 1.5 0.0053 16.9 0.1 2.0 2 0 0 2 2 2 1 EamA-like transporter family TPR_14 PF13428.6 EGC32904.1 - 7.7e-07 29.4 0.0 0.01 16.6 0.0 3.1 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC32904.1 - 0.00022 21.1 0.0 5.2 7.4 0.0 4.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC32904.1 - 0.00087 19.8 0.9 0.97 10.2 0.0 4.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32904.1 - 0.0011 18.7 0.2 0.37 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32904.1 - 0.0027 17.8 0.2 2.1 8.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32904.1 - 0.011 16.0 0.1 21 5.5 0.0 3.3 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC32904.1 - 0.043 14.3 0.2 0.32 11.5 0.0 2.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC32904.1 - 0.067 13.6 0.8 0.41 11.1 0.1 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat PHD PF00628.29 EGC32905.1 - 5.1e-19 67.9 23.9 1.1e-10 41.2 10.3 2.7 2 0 0 2 2 2 2 PHD-finger zf-HC5HC2H PF13771.6 EGC32905.1 - 6.1e-07 29.6 17.3 6.1e-06 26.4 1.6 3.5 3 0 0 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.6 EGC32905.1 - 5e-06 26.7 12.9 4.6e-05 23.5 1.1 3.1 2 1 0 2 2 2 2 PHD-zinc-finger like domain Prok-RING_1 PF14446.6 EGC32905.1 - 9.4e-06 25.5 11.9 5.3e-05 23.1 1.0 2.5 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 PHD_2 PF13831.6 EGC32905.1 - 1.5e-05 24.5 10.3 0.022 14.3 3.1 2.7 2 0 0 2 2 2 2 PHD-finger C1_2 PF03107.16 EGC32905.1 - 0.00079 19.7 3.0 0.00079 19.7 3.0 3.3 3 0 0 3 3 3 1 C1 domain PHF12_MRG_bd PF16737.5 EGC32905.1 - 0.004 16.8 0.0 0.011 15.4 0.0 1.8 1 0 0 1 1 1 1 PHD finger protein 12 MRG binding domain C1_1 PF00130.22 EGC32905.1 - 0.0075 16.1 1.7 0.0075 16.1 1.7 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGC32905.1 - 0.69 10.1 17.1 0.23 11.6 1.6 3.4 3 0 0 3 3 3 0 KIAA1045 RING finger zf-RING_2 PF13639.6 EGC32905.1 - 3.1 8.2 20.2 0.052 13.9 3.3 2.5 2 0 0 2 2 2 0 Ring finger domain ADK_lid PF05191.14 EGC32905.1 - 5.8 7.0 10.2 21 5.2 0.9 3.0 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-PHD-like PF15446.6 EGC32905.1 - 7.4 6.2 22.4 0.087 12.4 1.5 4.1 3 1 0 3 3 3 0 PHD/FYVE-zinc-finger like domain DUF4284 PF14112.6 EGC32906.1 - 0.034 15.1 1.7 0.034 15.1 1.7 2.0 1 1 1 2 2 2 0 Immunity protein 22 DUF4523 PF15023.6 EGC32906.1 - 0.068 13.0 1.1 0.084 12.7 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) MATH PF00917.26 EGC32907.1 - 2e-10 40.8 1.8 2e-10 40.8 1.8 2.4 3 0 0 3 3 3 1 MATH domain zf-TRAF PF02176.18 EGC32907.1 - 2.8e-09 37.5 37.7 8.1e-06 26.4 6.4 4.0 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC32907.1 - 1.4e-05 24.9 5.8 1.4e-05 24.9 5.8 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC32907.1 - 0.007 16.8 26.8 0.068 13.6 4.4 3.4 1 1 3 4 4 4 4 TRAF-like zinc-finger zf-C2H2_9 PF16293.5 EGC32907.1 - 0.019 14.8 0.5 2.7 7.9 0.0 3.1 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) Sina PF03145.16 EGC32907.1 - 0.02 14.9 28.0 0.77 9.7 13.5 3.7 1 1 2 3 3 3 0 Seven in absentia protein family LRR_4 PF12799.7 EGC32908.1 - 3e-08 33.8 37.9 0.049 14.1 0.9 8.6 3 2 5 8 8 8 7 Leucine Rich repeats (2 copies) Glyco_hydro_47 PF01532.20 EGC32908.1 - 0.037 12.9 0.1 0.055 12.4 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 LRR_6 PF13516.6 EGC32908.1 - 0.14 12.2 8.2 7.3 6.9 0.0 5.7 5 0 0 5 5 5 0 Leucine Rich repeat Swm2 PF17083.5 EGC32908.1 - 4.7 7.2 10.6 5.6 7.0 0.1 3.2 3 2 0 3 3 3 0 Nucleolar protein Swm2 Fer4 PF00037.27 EGC32909.1 - 1.3e-14 53.2 16.4 1.5e-08 34.1 4.5 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGC32909.1 - 5.5e-13 49.3 10.4 9.2e-13 48.6 10.4 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.6 EGC32909.1 - 7.7e-11 42.8 6.1 3.1e-05 24.8 0.2 2.4 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.6 EGC32909.1 - 2.2e-10 40.5 3.1 9.2e-05 22.5 0.3 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGC32909.1 - 7.7e-09 35.6 10.2 1.4e-08 34.8 10.2 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGC32909.1 - 1.6e-08 34.5 21.5 3.9e-06 26.9 12.7 2.1 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_6 PF12837.7 EGC32909.1 - 2.4e-07 30.6 17.8 0.00034 20.6 5.4 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.6 EGC32909.1 - 8.5e-07 29.3 19.4 0.00047 20.6 12.3 2.3 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGC32909.1 - 9e-07 28.6 12.5 0.0023 17.9 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_4 PF12800.7 EGC32909.1 - 4.2e-06 26.8 11.1 0.00031 21.0 2.0 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.6 EGC32909.1 - 0.00063 20.2 12.2 0.036 14.6 12.5 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGC32909.1 - 0.0067 17.0 13.9 0.34 11.5 3.6 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain of Ferredoxin I Fer4_18 PF13746.6 EGC32909.1 - 0.027 14.7 8.5 1.5 9.0 1.0 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain c-SKI_SMAD_bind PF08782.10 EGC32909.1 - 0.031 14.5 5.9 0.87 9.9 0.3 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain DUF4120 PF13496.6 EGC32909.1 - 0.11 12.9 0.0 3.8 8.0 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4120) Fer4_3 PF12798.7 EGC32909.1 - 0.15 13.1 16.3 0.3 12.1 4.1 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain ETF_QO PF05187.13 EGC32909.1 - 0.18 12.0 5.7 1.4 9.1 0.7 2.3 1 1 1 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S Fer4_22 PF17179.4 EGC32909.1 - 0.56 11.1 11.7 2.3 9.1 1.8 2.3 1 1 1 2 2 2 0 4Fe-4S dicluster domain G-alpha PF00503.20 EGC32910.1 - 2.3e-64 217.8 14.2 3.1e-64 217.4 14.2 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC32910.1 - 0.00084 18.8 0.6 0.092 12.2 0.1 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Sulfate_transp PF00916.20 EGC32911.1 - 7.3e-106 354.1 18.5 1.6e-105 353.0 18.5 1.5 1 1 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGC32911.1 - 1.7e-23 82.5 0.0 3.6e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.6 EGC32911.1 - 0.0011 19.2 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGC32911.1 - 0.015 15.7 4.4 0.015 15.7 4.4 3.0 3 1 0 3 3 3 0 Molybdate transporter of MFS superfamily cNMP_binding PF00027.29 EGC32912.1 - 9.3e-29 99.3 0.0 2.9e-15 56.1 0.0 2.9 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.27 EGC32912.1 - 1.3e-06 28.6 0.1 2.2e-06 27.8 0.1 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC32912.1 - 4.7e-05 23.0 0.0 8.1e-05 22.2 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Apis_Csd PF11671.8 EGC32912.1 - 0.0031 17.6 6.0 0.0088 16.1 6.0 1.8 1 0 0 1 1 1 1 Complementary sex determiner protein ANAPC4_WD40 PF12894.7 EGC32913.1 - 3.6e-08 33.6 0.1 0.037 14.3 0.0 4.5 2 2 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC32913.1 - 6.7e-05 23.6 2.2 13 6.9 0.0 5.9 7 0 0 7 7 7 1 WD domain, G-beta repeat eIF2A PF08662.11 EGC32913.1 - 0.00051 20.0 2.0 5.6 6.8 0.1 4.0 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A KTSC PF13619.6 EGC32913.1 - 0.05 13.4 0.1 11 5.9 0.0 2.8 2 0 0 2 2 2 0 KTSC domain PD40 PF07676.12 EGC32913.1 - 0.057 13.4 0.0 7.1 6.7 0.0 2.8 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat MIS13 PF08202.11 EGC32913.1 - 0.21 10.8 1.7 0.32 10.2 1.7 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Erf4 PF10256.9 EGC32914.1 - 0.00013 22.1 0.2 0.00049 20.2 0.2 1.9 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3040 PF11239.8 EGC32914.1 - 0.026 14.8 0.4 0.24 11.7 0.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3040) DUF373 PF04123.13 EGC32914.1 - 0.075 12.5 1.4 0.11 12.0 1.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF373) WSS_VP PF12175.8 EGC32914.1 - 0.077 12.5 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 White spot syndrome virus structural envelope protein VP DUF2207 PF09972.9 EGC32914.1 - 0.078 11.7 2.1 0.11 11.2 2.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) RseC_MucC PF04246.12 EGC32914.1 - 0.093 12.7 1.2 0.17 11.8 1.2 1.4 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Lactamase_B_2 PF12706.7 EGC32915.1 - 2e-09 37.3 0.2 2e-06 27.5 0.0 2.3 1 1 0 2 2 2 2 Beta-lactamase superfamily domain tRNA-synt_1e PF01406.19 EGC32916.1 - 6.3e-101 337.7 2.9 1.3e-100 336.7 2.9 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.11 EGC32916.1 - 1.6e-15 56.8 1.4 4.7e-08 32.2 0.3 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.18 EGC32916.1 - 0.00025 20.1 0.0 0.02 13.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (K) DALR_2 PF09190.11 EGC32916.1 - 0.068 13.7 0.1 0.2 12.2 0.1 1.8 1 0 0 1 1 1 0 DALR domain F-box-like PF12937.7 EGC32917.1 - 0.004 17.0 0.5 0.055 13.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like Carboxyl_trans PF01039.22 EGC32918.1 - 2.9e-190 633.1 0.0 3.4e-190 632.9 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.11 EGC32918.1 - 0.022 14.2 0.1 0.3 10.5 0.0 2.5 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) Longin PF13774.6 EGC32919.1 - 1.8e-25 88.8 0.0 3e-25 88.1 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGC32919.1 - 2.3e-25 88.2 3.2 3.6e-25 87.6 3.2 1.3 1 0 0 1 1 1 1 Synaptobrevin eIF-6 PF01912.18 EGC32920.1 - 1.8e-78 262.4 0.8 3.1e-78 261.7 0.7 1.4 2 0 0 2 2 2 1 eIF-6 family OTU PF02338.19 EGC32921.1 - 4e-12 46.7 0.0 1.1e-11 45.4 0.0 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease DUF1840 PF08895.11 EGC32921.1 - 0.091 13.1 10.8 1.1 9.6 0.6 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) M16C_assoc PF08367.11 EGC32921.1 - 3.1 6.9 9.5 4.9 6.2 9.5 1.2 1 0 0 1 1 1 0 Peptidase M16C associated p450 PF00067.22 EGC32922.1 - 6.4e-77 259.2 1.0 7.4e-77 259.0 1.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.21 EGC32923.1 - 2.8e-14 52.8 0.0 9e-12 44.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Suf PF05843.14 EGC32923.1 - 0.039 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Metallophos PF00149.28 EGC32924.1 - 1.4e-16 61.7 2.1 1.4e-16 61.7 2.1 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC32924.1 - 0.047 13.9 0.1 0.11 12.7 0.0 1.6 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain E1_DerP2_DerF2 PF02221.15 EGC32925.1 - 2.4e-24 86.3 0.3 2.7e-24 86.1 0.3 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGC32925.1 - 1.7e-05 25.2 0.5 2.8e-05 24.5 0.5 1.3 1 1 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.15 EGC32926.1 - 9e-22 77.9 0.7 1.1e-21 77.6 0.7 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.6 EGC32926.1 - 0.00044 20.6 0.2 0.0013 19.1 0.2 1.6 1 1 0 1 1 1 1 ML-like domain MCR_D PF02505.14 EGC32926.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.4 1 1 0 1 1 1 0 Methyl-coenzyme M reductase operon protein D tRNA-synt_1 PF00133.22 EGC32927.1 - 3.9e-218 725.6 0.3 5.2e-218 725.1 0.3 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC32927.1 - 1.2e-22 80.5 0.0 2.3e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGC32927.1 - 5e-14 51.9 1.1 0.00017 20.5 0.1 3.6 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.19 EGC32927.1 - 0.00026 20.5 0.0 0.00065 19.1 0.0 1.6 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2807 PF10988.8 EGC32927.1 - 0.022 14.6 1.0 0.039 13.7 1.0 1.3 1 0 0 1 1 1 0 Putative auto-transporter adhesin, head GIN domain ketoacyl-synt PF00109.26 EGC32929.1 - 2.2e-60 204.4 0.0 4.5e-60 203.3 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC32929.1 - 1.2e-39 136.8 0.0 1.9e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC32929.1 - 4.9e-32 110.4 0.0 7.9e-31 106.5 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EGC32929.1 - 1.3e-21 77.2 0.1 9.7e-21 74.4 0.0 2.8 2 0 0 2 2 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC32929.1 - 7.9e-17 61.7 0.3 3.6e-16 59.6 0.1 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC32929.1 - 2.6e-14 53.2 0.0 6.5e-09 35.4 0.0 2.2 1 1 1 2 2 2 2 Polyketide synthase dehydratase Methyltransf_25 PF13649.6 EGC32929.1 - 3.3e-06 27.7 0.0 2.6e-05 24.9 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC32929.1 - 9.4e-06 26.2 0.0 6.2e-05 23.6 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.12 EGC32929.1 - 1.3e-05 25.0 0.1 3.1e-05 23.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC32929.1 - 3.4e-05 23.4 0.1 7.6e-05 22.2 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC32929.1 - 9.3e-05 22.3 0.0 0.00025 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC32929.1 - 0.00018 21.8 0.1 0.00048 20.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.10 EGC32929.1 - 0.0011 19.0 0.0 1.1 9.1 0.0 2.6 1 1 1 2 2 2 2 KR domain Ubie_methyltran PF01209.18 EGC32929.1 - 0.0062 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.6 EGC32929.1 - 0.25 11.2 3.3 0.82 9.5 0.0 3.5 3 1 1 4 4 4 0 Methyltransferase domain DivIVA PF05103.13 EGC32930.1 - 0.053 13.6 4.1 0.053 13.6 1.9 1.9 1 1 1 2 2 2 0 DivIVA protein Bro-N PF02498.17 EGC32930.1 - 0.055 14.2 0.1 0.11 13.2 0.1 1.5 1 0 0 1 1 1 0 BRO family, N-terminal domain FNIP PF05725.12 EGC32931.1 - 5e-88 289.0 69.5 1.4e-13 50.8 3.7 10.7 7 3 6 13 13 13 12 FNIP Repeat LRR_5 PF13306.6 EGC32931.1 - 4.5e-07 29.9 6.0 0.15 12.0 0.1 4.4 2 2 3 5 5 5 4 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC32931.1 - 1.4 9.2 10.9 22 5.3 0.0 6.1 7 2 1 8 8 8 0 Protein of unknown function (DUF1769) FNIP PF05725.12 EGC32932.1 - 3.3e-173 561.7 72.6 4.3e-16 58.8 0.3 14.4 10 2 6 16 16 16 16 FNIP Repeat LRR_1 PF00560.33 EGC32932.1 - 0.021 15.3 32.8 37 5.4 0.3 13.4 5 4 4 9 9 9 0 Leucine Rich Repeat DUF3215 PF11503.8 EGC32932.1 - 0.072 13.0 3.9 26 4.8 0.0 6.1 8 0 0 8 8 8 0 Protein of unknown function (DUF3215) EGF_CA PF07645.15 EGC32933.1 - 2.8e-09 37.0 10.7 8.2e-07 29.1 0.8 2.1 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.7 EGC32933.1 - 7.5e-09 35.4 1.6 1.7e-08 34.2 1.6 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.6 EGC32933.1 - 5.3e-07 29.8 2.4 5.3e-07 29.8 2.4 2.1 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.7 EGC32933.1 - 0.00022 21.3 0.2 0.00022 21.3 0.2 2.6 2 1 0 2 2 2 1 EGF domain hEGF PF12661.7 EGC32933.1 - 0.0014 19.2 0.5 0.0014 19.2 0.5 2.7 2 1 0 2 2 2 1 Human growth factor-like EGF EGF PF00008.27 EGC32933.1 - 0.039 14.3 9.7 0.089 13.1 0.5 2.5 2 1 0 2 2 2 0 EGF-like domain Dimer_Tnp_hAT PF05699.14 EGC32935.1 - 4.1e-17 61.8 0.4 5.5e-17 61.3 0.4 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TatD_DNase PF01026.21 EGC32936.1 - 1.4e-63 214.6 0.0 1.7e-63 214.4 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase QueH PF02677.14 EGC32936.1 - 0.035 14.2 0.1 0.057 13.5 0.1 1.3 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH Amidohydro_2 PF04909.14 EGC32936.1 - 0.038 13.8 0.0 0.32 10.7 0.0 2.4 2 1 0 2 2 2 0 Amidohydrolase Fz PF01392.22 EGC32937.1 - 1.6e-07 32.0 2.7 3.7e-07 30.7 2.7 1.7 1 0 0 1 1 1 1 Fz domain Menin PF05053.13 EGC32937.1 - 0.42 8.9 9.9 0.58 8.4 9.9 1.1 1 0 0 1 1 1 0 Menin Abhydrolase_1 PF00561.20 EGC32938.1 - 3.7e-08 33.3 0.6 7.6e-08 32.3 0.6 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC32938.1 - 4.2e-07 30.8 0.0 4.9e-07 30.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC32938.1 - 1.2e-06 28.0 0.0 1.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC32938.1 - 0.00062 19.3 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.8 EGC32938.1 - 0.0032 16.7 0.0 0.0052 16.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Ndr PF03096.14 EGC32938.1 - 0.055 12.2 0.0 0.095 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family TPR_2 PF07719.17 EGC32939.1 - 2e-27 93.1 3.3 0.016 15.2 0.1 12.1 12 0 0 12 12 12 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGC32939.1 - 2.5e-21 75.7 0.8 3.5e-06 27.2 0.0 7.8 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC32939.1 - 6.6e-19 66.5 11.9 0.047 13.9 0.1 10.8 11 0 0 11 11 10 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGC32939.1 - 5.3e-18 64.0 11.4 0.012 15.4 0.1 10.1 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC32939.1 - 1.9e-16 59.5 2.0 0.48 10.2 0.0 7.9 6 2 2 8 8 8 4 TPR repeat TPR_19 PF14559.6 EGC32939.1 - 1.4e-15 57.6 0.9 0.00029 21.3 0.0 7.2 6 2 3 9 9 9 4 Tetratricopeptide repeat TPR_16 PF13432.6 EGC32939.1 - 1.5e-10 41.5 0.0 0.16 12.6 0.0 6.1 6 1 0 7 7 5 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC32939.1 - 2.5e-09 37.2 0.0 5.4 8.1 0.0 8.1 6 2 3 9 9 8 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC32939.1 - 3.3e-09 36.8 16.8 6.5e-05 23.1 0.0 7.2 6 2 3 10 10 10 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.6 EGC32939.1 - 9.9e-09 35.0 1.6 0.02 15.2 0.0 7.7 9 0 0 9 9 8 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC32939.1 - 5e-08 32.4 3.9 1.2 9.4 0.0 8.0 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC32939.1 - 5.7e-08 32.9 10.6 1.2 9.9 0.0 7.9 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGC32939.1 - 8.5e-06 25.5 3.2 19 5.3 0.0 6.4 6 0 0 6 6 6 0 Tetratricopeptide repeat BTAD PF03704.17 EGC32939.1 - 1.2e-05 25.8 0.3 0.013 15.9 0.0 3.8 5 0 0 5 5 4 1 Bacterial transcriptional activator domain TPR_20 PF14561.6 EGC32939.1 - 3.9e-05 23.9 1.2 2.8 8.3 0.1 5.5 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC32939.1 - 0.00019 21.5 0.1 1 9.6 0.0 4.7 6 1 1 7 7 6 1 Tetratricopeptide repeat NARP1 PF12569.8 EGC32939.1 - 0.00083 18.4 0.2 0.00083 18.4 0.2 4.9 4 2 1 5 5 4 1 NMDA receptor-regulated protein 1 ChAPs PF09295.10 EGC32939.1 - 0.0039 16.3 0.4 0.25 10.3 0.1 3.1 3 0 0 3 3 3 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_15 PF13429.6 EGC32939.1 - 0.0058 15.9 0.1 0.9 8.7 0.2 3.0 4 0 0 4 4 4 1 Tetratricopeptide repeat Foie-gras_1 PF11817.8 EGC32939.1 - 0.014 15.0 0.2 7.4 6.1 0.0 3.3 3 0 0 3 3 3 0 Foie gras liver health family 1 Alkyl_sulf_dimr PF14863.6 EGC32939.1 - 0.054 14.0 0.1 9.9 6.6 0.0 3.5 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation DUF4729 PF15866.5 EGC32939.1 - 0.081 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4729) BSP_II PF05432.11 EGC32939.1 - 1.3 8.7 33.7 0.027 14.2 25.6 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Clathrin PF00637.20 EGC32939.1 - 8.1 6.3 14.4 1.6 8.6 0.3 4.8 4 2 1 5 5 5 0 Region in Clathrin and VPS DUF647 PF04884.14 EGC32940.1 - 3.9e-77 259.1 1.6 4.9e-77 258.8 1.6 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis DUF4211 PF13926.6 EGC32940.1 - 0.048 13.7 1.2 0.085 12.9 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4211) Metallophos_C PF14008.6 EGC32941.1 - 4.7e-20 72.2 4.8 4.7e-20 72.2 1.0 3.0 3 0 0 3 3 3 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGC32941.1 - 2.3e-16 60.1 4.4 4.2e-16 59.3 0.8 2.8 3 0 0 3 3 3 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGC32941.1 - 1.1e-13 52.2 3.5 3.4e-13 50.6 3.5 1.8 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase fn3_PAP PF17808.1 EGC32941.1 - 0.038 14.1 0.1 3.9 7.6 0.0 2.9 1 1 1 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase TelA PF05816.11 EGC32942.1 - 0.091 11.8 0.1 0.09 11.8 0.1 1.0 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Metallophos PF00149.28 EGC32943.1 - 2.2e-18 67.5 5.2 3.7e-18 66.8 5.2 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC32943.1 - 0.11 12.7 0.0 0.36 11.0 0.0 1.8 2 0 0 2 2 2 0 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.22 EGC32944.1 - 1.1e-07 31.6 0.1 8.6e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad52_Rad22 PF04098.15 EGC32944.1 - 1.8e-07 31.2 0.6 3.2e-07 30.4 0.6 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein PhetRS_B1 PF18262.1 EGC32944.1 - 0.34 11.2 3.5 0.45 10.8 0.0 2.6 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain Ribosomal_S9 PF00380.19 EGC32945.1 - 6.3e-34 117.1 0.4 7.3e-34 116.9 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3430 PF11912.8 EGC32947.1 - 1.4e-28 100.4 27.1 1.6e-28 100.2 27.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) V-ATPase_C PF03223.15 EGC32948.1 - 8.8e-119 397.2 6.8 1.1e-118 396.9 6.8 1.0 1 0 0 1 1 1 1 V-ATPase subunit C APG17 PF04108.12 EGC32948.1 - 0.032 13.4 1.2 0.054 12.6 1.2 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 JAMP PF05571.12 EGC32949.1 - 0.096 12.3 4.6 0.12 12.0 4.6 1.2 1 0 0 1 1 1 0 JNK1/MAPK8-associated membrane protein zf-TRAF PF02176.18 EGC32949.1 - 1.3 9.8 8.1 3 8.6 0.0 3.3 2 1 1 3 3 3 0 TRAF-type zinc finger DPBB_1 PF03330.18 EGC32950.1 - 2.8e-06 27.5 0.8 6.7e-06 26.3 0.1 2.0 2 1 0 2 2 2 1 Lytic transglycolase LysM PF01476.20 EGC32950.1 - 0.0061 16.6 0.1 3.8 7.7 0.0 2.4 2 0 0 2 2 2 2 LysM domain Gp138_N PF18352.1 EGC32950.1 - 0.049 13.7 1.5 2.8 8.1 0.1 2.7 3 0 0 3 3 3 0 Phage protein Gp138 N-terminal domain SapB_2 PF03489.17 EGC32950.1 - 0.09 12.9 0.0 10 6.4 0.0 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 2 Ribosomal_L26 PF16906.5 EGC32951.1 - 3.1e-35 120.5 2.3 4.2e-35 120.1 2.3 1.2 1 0 0 1 1 1 1 Ribosomal proteins L26 eukaryotic, L24P archaeal KOW PF00467.29 EGC32951.1 - 0.00017 21.4 1.5 0.00017 21.4 1.5 2.2 3 0 0 3 3 3 1 KOW motif Methyltrans_RNA PF04452.14 EGC32951.1 - 0.04 13.3 0.3 0.054 12.8 0.2 1.3 1 1 0 1 1 1 0 RNA methyltransferase U-box PF04564.15 EGC32952.1 - 4.5e-14 52.4 0.3 9.3e-14 51.4 0.3 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.8 EGC32952.1 - 1.8e-08 34.1 0.3 3.7e-08 33.0 0.3 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.7 EGC32952.1 - 5.6e-08 33.0 0.6 1.5e-07 31.6 0.1 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC32952.1 - 1.2e-06 28.8 0.1 2.4e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC32952.1 - 3.2e-06 26.9 0.2 8.2e-06 25.6 0.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_1 PF00583.25 EGC32952.1 - 3.7e-06 27.2 0.0 7.1e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family zf-RING_UBOX PF13445.6 EGC32952.1 - 1.3e-05 25.1 0.4 0.00017 21.5 0.0 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC32952.1 - 0.00013 21.7 0.2 0.00027 20.7 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_10 PF13673.7 EGC32952.1 - 0.00015 21.7 0.2 0.00047 20.1 0.1 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC32952.1 - 0.0002 21.7 0.0 0.00052 20.4 0.0 1.6 2 0 0 2 2 1 1 Acetyltransferase (GNAT) domain Rtf2 PF04641.12 EGC32952.1 - 0.0014 18.1 0.1 0.0024 17.3 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger Prok-RING_4 PF14447.6 EGC32952.1 - 0.0044 16.9 0.1 0.0083 16.0 0.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC32952.1 - 0.0084 16.1 0.1 0.016 15.2 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC32952.1 - 0.017 15.1 0.1 0.041 13.8 0.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC32952.1 - 0.025 14.4 0.1 0.047 13.6 0.1 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC32952.1 - 0.033 14.3 0.4 0.18 12.0 0.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF5397 PF17375.2 EGC32952.1 - 0.035 13.8 0.0 0.072 12.8 0.0 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5397) FR47 PF08445.10 EGC32952.1 - 0.16 12.0 0.0 0.37 10.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Isochorismatase PF00857.20 EGC32953.1 - 2.8e-17 63.4 0.0 3.4e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.20 EGC32954.1 - 5.5e-31 108.1 0.1 6.7e-31 107.8 0.1 1.1 1 0 0 1 1 1 1 Isochorismatase family TFIID-18kDa PF02269.16 EGC32954.1 - 0.068 13.2 0.2 0.16 12.0 0.2 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit HP0268 PF18618.1 EGC32954.1 - 0.13 12.7 6.7 0.19 12.2 1.0 2.8 3 1 0 3 3 3 0 HP0268 THF_DHG_CYH_C PF02882.19 EGC32955.1 - 6.5e-74 246.6 1.8 9.7e-74 246.0 0.6 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.23 EGC32955.1 - 6.7e-38 129.5 2.2 1.2e-37 128.7 2.2 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain AlaDh_PNT_C PF01262.21 EGC32955.1 - 0.065 12.5 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Ligase_CoA PF00549.19 EGC32955.1 - 0.16 11.7 0.7 23 4.8 0.0 2.9 2 2 1 3 3 3 0 CoA-ligase DSPc PF00782.20 EGC32956.1 - 1.6e-06 28.0 0.0 2.9e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.13 EGC32956.1 - 0.059 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGC32956.1 - 0.072 12.6 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGC32956.1 - 0.079 12.9 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Tyrosine phosphatase family VPR PF00522.18 EGC32956.1 - 0.16 12.1 0.0 0.24 11.4 0.0 1.3 1 0 0 1 1 1 0 VPR/VPX protein Beach PF02138.18 EGC32957.1 - 5.1e-119 396.7 3.0 9.3e-119 395.9 3.0 1.5 1 0 0 1 1 1 1 Beige/BEACH domain DUF4704 PF15787.5 EGC32957.1 - 5.1e-23 81.7 1.5 1.4e-22 80.2 1.5 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EGC32957.1 - 2.7e-19 69.1 0.0 1.3e-18 67.0 0.0 2.3 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EGC32957.1 - 1.6e-12 47.8 0.0 5.9e-12 46.0 0.0 2.0 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.32 EGC32957.1 - 1.2e-05 25.9 7.7 0.0081 17.0 0.2 4.5 4 0 0 4 4 4 2 WD domain, G-beta repeat Sec3-PIP2_bind PF15277.6 EGC32957.1 - 0.036 14.2 0.7 4.7 7.4 0.1 3.0 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH GRAM PF02893.20 EGC32957.1 - 0.053 13.4 0.1 0.19 11.6 0.1 2.0 1 0 0 1 1 1 0 GRAM domain ParBc PF02195.18 EGC32958.1 - 2.2e-11 43.9 0.0 2.6e-11 43.7 0.0 1.0 1 0 0 1 1 1 1 ParB-like nuclease domain HD PF01966.22 EGC32959.1 - 0.00016 21.9 0.0 0.00025 21.2 0.0 1.3 1 0 0 1 1 1 1 HD domain Xpo1 PF08389.12 EGC32961.1 - 5e-36 124.0 10.8 6e-36 123.7 2.7 4.0 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.19 EGC32961.1 - 0.00074 19.4 1.2 0.12 12.3 0.1 4.1 3 1 1 4 4 4 1 Importin-beta N-terminal domain Ribosomal_L9_N PF01281.19 EGC32962.1 - 1.5e-17 62.9 0.0 3.1e-17 61.9 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.14 EGC32962.1 - 4.8e-06 27.0 0.7 9.6e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain zf-HC5HC2H_2 PF13832.6 EGC32963.1 - 7.8e-22 77.5 4.4 7.8e-22 77.5 4.4 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Bromodomain PF00439.25 EGC32963.1 - 1.5e-16 60.2 1.8 5.9e-16 58.3 1.8 2.1 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.6 EGC32963.1 - 8.3e-16 58.0 2.2 8.3e-16 58.0 2.2 3.8 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.6 EGC32963.1 - 4.3e-14 51.8 7.3 1.4e-13 50.1 3.1 2.8 2 0 0 2 2 2 1 PHD-finger PHD PF00628.29 EGC32963.1 - 1.4e-11 44.1 24.9 6.1e-10 38.8 6.0 3.5 3 1 0 3 3 3 2 PHD-finger EPL1 PF10513.9 EGC32963.1 - 1.1e-08 35.6 68.8 1.1e-08 35.6 68.8 8.8 2 2 1 5 5 5 1 Enhancer of polycomb-like zf-RING-like PF08746.11 EGC32963.1 - 0.0074 16.6 4.3 0.0074 16.6 4.3 2.7 2 0 0 2 2 2 1 RING-like domain C1_1 PF00130.22 EGC32963.1 - 0.02 14.8 0.6 0.02 14.8 0.6 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) bMG10 PF17973.1 EGC32963.1 - 0.074 13.3 1.0 0.61 10.3 1.0 2.7 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG10 domain DUF4428 PF14471.6 EGC32963.1 - 0.47 10.4 8.1 0.31 11.0 0.5 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4428) DNA_ligase_A_M PF01068.21 EGC32964.1 - 4.6e-53 179.9 0.1 1.1e-52 178.6 0.1 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGC32964.1 - 4.4e-30 105.3 1.8 2.2e-29 103.0 0.5 2.6 2 0 0 2 2 2 1 DNA ligase N terminus BRCT_2 PF16589.5 EGC32964.1 - 7.4e-17 61.5 8.0 6.6e-11 42.5 0.1 4.7 5 0 0 5 5 5 2 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC32964.1 - 5.4e-16 58.7 12.1 1.2e-10 41.6 0.3 4.6 5 0 0 5 5 5 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.15 EGC32964.1 - 9e-16 58.3 0.0 2.9e-15 56.7 0.0 2.0 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region LIG3_BRCT PF16759.5 EGC32964.1 - 7.4e-15 55.0 0.1 3.3e-13 49.7 0.0 3.2 2 0 0 2 2 2 1 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGC32964.1 - 6.1e-12 45.3 0.1 6.4e-05 22.8 0.0 2.9 2 0 0 2 2 2 2 twin BRCT domain RNA_ligase PF09414.10 EGC32964.1 - 2.1e-10 41.2 0.2 5.4e-10 39.8 0.2 1.7 1 0 0 1 1 1 1 RNA ligase DUF913 PF06025.12 EGC32964.1 - 0.75 8.7 19.2 0.71 8.8 0.3 3.7 4 0 0 4 4 4 0 Domain of Unknown Function (DUF913) ABA_GPCR PF12430.8 EGC32965.1 - 3.6e-40 137.7 10.2 3.6e-40 137.7 10.2 1.9 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor GPHR_N PF12537.8 EGC32965.1 - 3.2e-21 75.2 0.0 2.7e-20 72.2 0.0 2.4 3 0 0 3 3 3 1 The Golgi pH Regulator (GPHR) Family N-terminal DUF465 PF04325.13 EGC32965.1 - 0.033 14.2 6.0 0.033 14.2 6.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Phage-scaffold PF09306.10 EGC32966.1 - 0.063 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein Endotoxin_C2 PF18449.1 EGC32968.1 - 0.094 13.1 1.2 1.6 9.1 0.1 2.3 2 0 0 2 2 2 0 Delta endotoxin AhpC-TSA PF00578.21 EGC32969.1 - 1.3e-42 144.6 0.1 1.6e-42 144.3 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC32969.1 - 2e-25 89.2 0.1 2.3e-25 89.1 0.1 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGC32969.1 - 0.00059 19.9 0.0 0.00091 19.3 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 EGC32969.1 - 0.013 15.8 0.0 0.022 15.0 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like YwhD PF08741.10 EGC32969.1 - 0.051 13.2 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 YwhD family Ribosomal_S7e PF01251.18 EGC32970.1 - 2.6e-77 258.7 7.4 3e-77 258.6 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Snf7 PF03357.21 EGC32971.1 - 2.9e-41 140.9 17.9 3.4e-41 140.7 17.9 1.0 1 0 0 1 1 1 1 Snf7 DUF285 PF03382.14 EGC32971.1 - 0.0067 16.2 3.2 0.014 15.1 2.0 2.0 2 0 0 2 2 2 1 Mycoplasma protein of unknown function, DUF285 Hydantoinase_B PF02538.14 EGC32971.1 - 0.011 14.1 1.2 0.013 13.9 1.2 1.1 1 0 0 1 1 1 0 Hydantoinase B/oxoprolinase DUF2443 PF10398.9 EGC32971.1 - 0.015 15.3 0.7 0.68 10.0 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) ORF6C PF10552.9 EGC32971.1 - 0.055 13.6 7.2 0.071 13.2 1.3 2.2 2 0 0 2 2 2 0 ORF6C domain Prefoldin PF02996.17 EGC32971.1 - 0.058 13.3 0.3 0.058 13.3 0.3 3.3 1 1 2 3 3 3 0 Prefoldin subunit DUF5624 PF18538.1 EGC32971.1 - 0.058 13.5 1.4 0.088 12.9 0.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF5624) Evr1_Alr PF04777.13 EGC32971.1 - 0.06 13.8 0.2 0.1 13.0 0.2 1.4 1 0 0 1 1 1 0 Erv1 / Alr family Phage_lysozyme PF00959.19 EGC32971.1 - 0.12 12.8 3.3 0.26 11.8 3.3 1.6 1 1 0 1 1 1 0 Phage lysozyme DUF4665 PF15679.5 EGC32971.1 - 0.15 12.7 7.4 2.4 8.9 0.3 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) Cauli_DNA-bind PF03310.13 EGC32971.1 - 0.22 11.6 2.9 0.13 12.4 0.8 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Pup PF05639.11 EGC32971.1 - 0.27 12.1 3.8 0.44 11.5 2.8 2.0 1 1 0 1 1 1 0 Pup-like protein DUF948 PF06103.11 EGC32971.1 - 2.3 8.5 8.1 39 4.6 4.5 2.5 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Prominin PF05478.11 EGC32971.1 - 4.4 5.1 7.5 3.2 5.6 6.0 1.4 1 1 0 1 1 1 0 Prominin YabA PF06156.13 EGC32971.1 - 10 6.9 12.7 3.6 8.3 3.3 2.3 1 1 1 2 2 2 0 Initiation control protein YabA HipN PF18253.1 EGC32972.1 - 0.13 12.0 0.2 0.22 11.2 0.2 1.4 1 0 0 1 1 1 0 Hsp70-interacting protein N N-terminal domain DUF155 PF02582.14 EGC32973.1 - 2.1e-28 99.6 0.4 2.1e-28 99.6 0.4 2.2 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Actin PF00022.19 EGC32974.1 - 4.3e-83 279.2 0.1 2e-81 273.7 0.1 2.0 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGC32974.1 - 4.1e-05 22.6 0.1 0.00013 20.9 0.1 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Bundlin PF05307.11 EGC32974.1 - 0.028 14.2 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Bundlin Archease PF01951.16 EGC32974.1 - 0.15 12.3 0.2 8.2 6.7 0.0 2.3 2 0 0 2 2 2 0 Archease protein family (MTH1598/TM1083) K_trans PF02705.16 EGC32975.1 - 1.3e-188 627.9 23.4 1.6e-188 627.6 23.4 1.0 1 0 0 1 1 1 1 K+ potassium transporter RNA_pol_3_Rpc31 PF11705.8 EGC32976.1 - 1.8e-06 28.4 15.0 1.8e-06 28.4 15.0 1.5 1 1 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 DUF3295 PF11702.8 EGC32976.1 - 0.63 9.3 5.2 0.78 9.0 5.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Astro_capsid_p PF12226.8 EGC32976.1 - 0.72 9.0 9.2 0.93 8.6 9.2 1.2 1 0 0 1 1 1 0 Turkey astrovirus capsid protein Pox_Ag35 PF03286.14 EGC32976.1 - 1.4 8.7 8.3 2.3 8.0 8.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein PPP4R2 PF09184.11 EGC32976.1 - 1.6 8.3 17.3 1.1 8.8 10.6 2.2 2 0 0 2 2 2 0 PPP4R2 CDC45 PF02724.14 EGC32976.1 - 3 6.0 6.8 3.3 5.9 6.8 1.1 1 0 0 1 1 1 0 CDC45-like protein Nop14 PF04147.12 EGC32976.1 - 3.1 5.9 12.9 3.5 5.7 12.9 1.2 1 0 0 1 1 1 0 Nop14-like family RNA_pol_3_Rpc31 PF11705.8 EGC32977.1 - 2.6e-05 24.6 9.1 2.6e-05 24.6 9.1 1.9 2 0 0 2 2 2 1 DNA-directed RNA polymerase III subunit Rpc31 DUF5511 PF17630.2 EGC32977.1 - 0.082 13.1 0.2 0.13 12.4 0.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5511) Pox_Ag35 PF03286.14 EGC32977.1 - 3.7 7.3 8.1 0.57 9.9 4.3 1.7 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF3295 PF11702.8 EGC32977.1 - 6.5 6.0 6.8 7.8 5.7 6.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Transket_pyr PF02779.24 EGC32978.1 - 6.5e-67 224.6 0.0 1e-66 224.0 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.20 EGC32978.1 - 1.5e-63 214.5 0.1 2.2e-63 214.0 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component OxoGdeHyase_C PF16870.5 EGC32978.1 - 2.8e-46 157.0 0.0 4.9e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal 2-oxogl_dehyd_N PF16078.5 EGC32978.1 - 1.6e-18 66.0 0.9 7e-18 63.9 0.9 2.2 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase N-terminus GNT-I PF03071.15 EGC32979.1 - 2.4e-82 277.0 11.7 3.2e-82 276.6 11.4 1.3 1 1 0 1 1 1 1 GNT-I family TMF_DNA_bd PF12329.8 EGC32979.1 - 0.0018 18.2 5.8 0.0035 17.3 5.8 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding FAM176 PF14851.6 EGC32979.1 - 0.09 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 FAM176 family DUF4446 PF14584.6 EGC32979.1 - 0.096 12.7 5.5 0.061 13.3 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Atg14 PF10186.9 EGC32979.1 - 0.16 11.0 4.2 0.3 10.1 4.2 1.4 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Cep57_CLD_2 PF14197.6 EGC32979.1 - 0.2 11.8 1.4 0.38 10.9 1.4 1.5 1 0 0 1 1 1 0 Centrosome localisation domain of PPC89 Lebercilin PF15619.6 EGC32979.1 - 0.75 9.4 7.2 1.3 8.7 7.2 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF5585 PF17823.1 EGC32980.1 - 0.2 10.6 24.8 0.36 9.7 24.8 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5585) RRM_1 PF00076.22 EGC32981.1 - 5.9e-11 42.0 0.2 3.2e-05 23.7 0.1 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RET_CLD3 PF17812.1 EGC32981.1 - 0.019 15.2 0.1 0.038 14.2 0.1 1.5 1 0 0 1 1 1 0 RET Cadherin like domain 3 DivIC PF04977.15 EGC32981.1 - 0.026 14.3 0.8 0.026 14.3 0.8 2.5 3 0 0 3 3 3 0 Septum formation initiator Phage_gp53 PF11246.8 EGC32981.1 - 1 9.0 11.7 0.032 13.9 5.1 1.8 2 0 0 2 2 2 0 Base plate wedge protein 53 Aldedh PF00171.22 EGC32982.1 - 6.2e-164 545.9 0.0 6.9e-164 545.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3430 PF11912.8 EGC32983.1 - 1.6e-19 70.8 24.1 1.9e-19 70.6 24.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Ribosomal_S15 PF00312.22 EGC32984.1 - 0.055 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal protein S15 Ist1 PF03398.14 EGC32985.1 - 2e-52 177.5 6.6 2.7e-52 177.0 6.6 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway TFIIA PF03153.13 EGC32985.1 - 1.3 8.9 20.0 1.8 8.4 20.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.12 EGC32986.1 - 3.1e-180 584.2 69.4 1e-15 57.6 0.2 14.3 5 2 9 17 17 17 16 FNIP Repeat DUF1769 PF08588.10 EGC32986.1 - 0.00021 21.5 7.4 37 4.6 0.0 9.0 8 2 2 10 10 10 1 Protein of unknown function (DUF1769) Phage_min_tail PF05939.13 EGC32986.1 - 0.083 13.3 0.0 1.3e+02 3.0 0.0 5.2 5 1 1 6 6 6 0 Phage minor tail protein Oxidored_q4 PF00507.19 EGC32986.1 - 0.17 12.0 0.0 0.3 11.3 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 FAD_binding_1 PF00667.20 EGC32987.1 - 2.6e-42 144.9 0.1 4.8e-42 144.0 0.1 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGC32987.1 - 2.1e-28 99.3 0.0 3.5e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.21 EGC32987.1 - 5.3e-13 49.6 0.0 1.2e-12 48.4 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain DUF3402 PF11882.8 EGC32988.1 - 1.9e-48 165.7 25.5 1.6e-30 106.6 6.9 3.3 2 1 1 3 3 3 3 Domain of unknown function (DUF3402) N1221 PF07923.13 EGC32988.1 - 8.8e-29 100.6 8.5 8.8e-29 100.6 8.5 2.1 2 1 0 2 2 2 1 N1221-like protein MafB19-deam PF14437.6 EGC32989.1 - 1.7e-24 86.2 0.1 2.7e-24 85.5 0.1 1.5 1 1 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EGC32989.1 - 3.7e-23 81.3 0.3 7.5e-23 80.3 0.3 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Inv-AAD PF18785.1 EGC32989.1 - 0.0015 18.4 0.1 0.0026 17.6 0.1 1.5 1 0 0 1 1 1 1 Invertebrate-AID/APOBEC-deaminase SNAD4 PF18750.1 EGC32989.1 - 0.016 15.3 0.0 0.047 13.8 0.0 1.7 1 0 0 1 1 1 0 Secreted Novel AID/APOBEC-like Deaminase 4 Bd3614-deam PF14439.6 EGC32989.1 - 0.61 10.2 3.4 3 7.9 3.4 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase CTP_transf_like PF01467.26 EGC32990.1 - 8.8e-06 26.0 0.2 2.4e-05 24.5 0.0 1.8 2 0 0 2 2 2 1 Cytidylyltransferase-like Arabino_trans_C PF14896.6 EGC32991.1 - 0.043 12.8 0.2 0.056 12.4 0.2 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain Ashwin PF15323.6 EGC32991.1 - 0.11 12.5 4.6 0.15 12.1 4.6 1.2 1 0 0 1 1 1 0 Developmental protein Sulfotransfer_2 PF03567.14 EGC32992.1 - 5e-11 43.0 0.6 5e-11 43.0 0.6 2.6 2 1 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGC32992.1 - 0.0015 17.5 0.1 0.004 16.1 0.1 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase HTH_38 PF13936.6 EGC32992.1 - 0.82 9.5 4.0 31 4.4 0.0 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Ndc1_Nup PF09531.10 EGC32992.1 - 3.6 6.2 5.9 6.2 5.4 5.9 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Sulfotransfer_2 PF03567.14 EGC32993.1 - 3.6e-11 43.5 2.9 1.1e-10 41.9 2.9 1.8 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGC32993.1 - 0.0006 18.8 0.4 0.0014 17.6 0.4 1.7 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase FidL_like PF15941.5 EGC32993.1 - 0.2 12.1 5.2 0.76 10.3 5.2 2.0 1 0 0 1 1 1 0 FidL-like putative membrane protein O-antigen_lig PF13425.6 EGC32993.1 - 0.69 8.6 9.6 1 8.1 9.6 1.2 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Sulfotransfer_2 PF03567.14 EGC32994.1 - 1.9e-10 41.1 0.3 1.9e-10 41.1 0.3 2.0 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.11 EGC32994.1 - 0.0014 17.6 0.0 0.0031 16.4 0.0 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.27 EGC32994.1 - 0.072 12.6 1.9 0.092 12.2 0.1 2.0 1 1 0 2 2 2 0 Sulfotransferase domain 7TM_GPCR_Srd PF10317.9 EGC32994.1 - 0.12 11.5 0.9 0.18 11.0 0.9 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd 2OG-FeII_Oxy_3 PF13640.6 EGC32995.1 - 5e-08 33.7 0.0 1.1e-07 32.6 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily GIT1_C PF12205.8 EGC32995.1 - 0.032 14.4 2.3 0.16 12.1 0.2 3.0 3 0 0 3 3 3 0 G protein-coupled receptor kinase-interacting protein 1 C term Gemini_AL1_M PF08283.11 EGC32995.1 - 0.26 11.4 4.4 0.31 11.1 1.2 2.8 2 0 0 2 2 2 0 Geminivirus rep protein central domain DUF1722 PF08349.11 EGC32995.1 - 1 9.7 7.0 0.32 11.3 0.5 3.6 4 1 1 5 5 5 0 Protein of unknown function (DUF1722) OmpH PF03938.14 EGC32996.1 - 1.5e-07 31.8 53.9 0.0057 17.0 5.5 4.3 3 1 1 4 4 4 4 Outer membrane protein (OmpH-like) Spc7 PF08317.11 EGC32996.1 - 0.00034 19.6 43.0 0.00081 18.4 22.4 3.3 3 0 0 3 3 3 2 Spc7 kinetochore protein Serine_rich PF08824.10 EGC32996.1 - 0.096 12.7 13.0 0.094 12.7 1.7 3.5 3 1 1 4 4 4 0 Serine rich protein interaction domain Mobilization_B PF17511.2 EGC32996.1 - 0.21 11.9 6.2 0.075 13.4 0.7 2.8 3 0 0 3 3 3 0 Mobilization protein B Talin_middle PF09141.10 EGC32996.1 - 0.3 11.1 12.1 0.047 13.7 1.2 3.3 3 0 0 3 3 3 0 Talin, middle domain Retrotrans_gag PF03732.17 EGC32996.1 - 0.35 11.2 5.0 0.97 9.7 0.3 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein RHSP PF07999.11 EGC32996.1 - 0.65 8.8 8.4 0.06 12.2 3.7 1.6 2 0 0 2 2 2 0 Retrotransposon hot spot protein Syntaxin PF00804.25 EGC32996.1 - 1.1 8.9 30.7 0.051 13.2 13.8 3.3 3 0 0 3 3 3 0 Syntaxin DUF4407 PF14362.6 EGC32996.1 - 1.4 8.2 29.4 0.52 9.6 13.0 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4407) Fez1 PF06818.15 EGC32996.1 - 3.2 8.2 42.6 1.4 9.3 23.2 3.2 2 1 1 3 3 3 0 Fez1 SbcD_C PF12320.8 EGC32996.1 - 4.6 7.6 10.1 0.76 10.1 3.1 3.3 3 1 0 3 3 3 0 Type 5 capsule protein repressor C-terminal domain Ribosomal_L17 PF01196.19 EGC32996.1 - 9.6 7.2 12.2 4.6e+02 1.8 11.8 3.0 1 1 0 1 1 1 0 Ribosomal protein L17 NADH-u_ox-rdase PF10785.9 EGC32997.1 - 1.9e-09 38.1 0.5 2.6e-09 37.6 0.5 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SesA PF17107.5 EGC32998.1 - 0.093 12.9 0.0 0.18 12.0 0.0 1.4 1 0 0 1 1 1 0 N-terminal domain on NACHT_NTPase and P-loop NTPases FNIP PF05725.12 EGC32999.1 - 4.6e-55 183.5 56.9 2.8e-15 56.2 0.6 6.3 2 2 3 7 7 7 7 FNIP Repeat RED_C PF07807.11 EGC32999.1 - 8.3 6.9 5.9 0.74 10.3 1.4 1.5 2 0 0 2 2 2 0 RED-like protein C-terminal region DNA_primase_lrg PF04104.14 EGC33000.1 - 7.1e-66 222.3 0.3 1.1e-65 221.7 0.3 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit DUF2024 PF09630.10 EGC33000.1 - 0.065 13.1 0.9 11 6.0 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF2024) Ribosomal_L7Ae PF01248.26 EGC33001.1 - 8.7e-21 73.5 0.0 1e-20 73.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_22 PF13401.6 EGC33002.1 - 0.00073 19.8 0.0 0.002 18.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain TniB PF05621.11 EGC33002.1 - 0.0048 16.3 0.1 0.042 13.3 0.1 2.4 2 0 0 2 2 2 1 Bacterial TniB protein MJ1316 PF04457.12 EGC33003.1 - 3.1e-11 43.8 2.0 5.3e-11 43.1 0.5 2.2 2 1 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain PA26 PF04636.13 EGC33003.1 - 0.034 13.1 2.0 0.05 12.5 2.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Ras PF00071.22 EGC33004.1 - 4.1e-43 146.8 0.7 4.8e-43 146.5 0.7 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33004.1 - 7.2e-23 81.1 0.1 1.2e-22 80.4 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC33004.1 - 1.2e-05 24.9 0.2 1.3e-05 24.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC33004.1 - 9.2e-05 21.9 0.4 0.00011 21.6 0.4 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC33004.1 - 0.0036 16.9 0.1 0.21 11.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC33004.1 - 0.0072 16.3 0.1 2.7 7.9 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase AAA_5 PF07728.14 EGC33004.1 - 0.018 15.0 0.0 0.029 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.9 EGC33004.1 - 0.032 14.0 0.1 0.3 10.8 0.0 2.2 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGC33004.1 - 0.054 13.1 0.0 0.93 9.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TsaE PF02367.17 EGC33004.1 - 0.062 13.3 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGC33004.1 - 0.079 13.1 0.0 0.44 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGC33004.1 - 0.12 12.5 0.0 0.3 11.2 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase UPF0242 PF06785.11 EGC33005.1 - 0.0026 17.9 2.8 0.0026 17.9 2.8 2.5 2 1 0 2 2 2 1 Uncharacterised protein family (UPF0242) N-terminus Fez1 PF06818.15 EGC33005.1 - 0.023 15.2 9.7 0.085 13.3 3.9 2.2 2 0 0 2 2 2 0 Fez1 LisH_TPL PF17814.1 EGC33005.1 - 0.024 14.3 0.5 0.072 12.8 0.5 1.9 1 0 0 1 1 1 0 LisH-like dimerisation domain T3SSipB PF16535.5 EGC33005.1 - 0.032 14.7 3.2 0.11 13.0 3.2 2.0 1 1 0 1 1 1 0 Type III cell invasion protein SipB BLOC1_2 PF10046.9 EGC33005.1 - 0.038 14.3 3.3 0.038 14.3 3.3 3.7 3 2 2 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 GCN5L1 PF06320.13 EGC33005.1 - 0.24 11.6 6.9 0.6 10.3 3.2 2.9 2 1 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) TIR-like PF10137.9 EGC33005.1 - 0.26 11.3 6.2 6.9 6.7 0.2 2.8 2 1 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain MAD PF05557.13 EGC33005.1 - 0.28 9.5 16.5 0.013 14.0 3.9 2.4 2 1 0 2 2 2 0 Mitotic checkpoint protein DUF3394 PF11874.8 EGC33005.1 - 0.49 10.1 3.2 0.21 11.2 0.5 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3394) Apolipoprotein PF01442.18 EGC33005.1 - 0.68 9.8 5.9 0.42 10.5 2.8 2.2 2 1 1 3 3 3 0 Apolipoprotein A1/A4/E domain ApoLp-III PF07464.11 EGC33005.1 - 0.95 9.5 20.1 0.034 14.2 6.9 2.9 2 1 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Fzo_mitofusin PF04799.13 EGC33005.1 - 1.4 8.4 14.0 0.072 12.6 5.4 2.9 2 2 1 3 3 3 0 fzo-like conserved region TMPIT PF07851.13 EGC33005.1 - 1.5 8.0 14.1 1.9 7.6 4.1 2.2 2 0 0 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 EGC33005.1 - 1.9 9.0 11.2 1.5 9.4 5.1 2.7 2 1 1 3 3 3 0 Apg6 coiled-coil region DUF745 PF05335.13 EGC33005.1 - 2.3 7.9 8.7 4 7.1 2.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) PRKG1_interact PF15898.5 EGC33005.1 - 2.6 9.0 15.2 6.6 7.7 1.0 2.9 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain HIP1_clath_bdg PF16515.5 EGC33005.1 - 2.9 8.6 12.2 0.14 12.8 1.0 3.3 3 1 0 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF2203 PF09969.9 EGC33005.1 - 4.5 8.0 6.4 1.9 9.3 0.7 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF2959 PF11172.8 EGC33005.1 - 4.6 7.3 12.7 3.5 7.7 0.8 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) Snapin_Pallidin PF14712.6 EGC33005.1 - 5.9 7.4 15.7 0.52 10.8 1.7 3.7 2 2 2 4 4 4 0 Snapin/Pallidin FliD_N PF02465.18 EGC33005.1 - 6.7 7.5 11.9 1.2 9.9 4.4 2.9 2 2 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Seryl_tRNA_N PF02403.22 EGC33005.1 - 7.3 6.9 21.8 0.14 12.4 7.5 3.6 2 1 1 4 4 3 0 Seryl-tRNA synthetase N-terminal domain PCRF PF03462.18 EGC33005.1 - 8 6.3 11.4 0.68 9.8 3.5 2.2 2 0 0 2 2 2 0 PCRF domain CC2-LZ PF16516.5 EGC33005.1 - 8.2 6.9 13.6 0.6 10.5 3.2 3.2 3 1 0 3 3 3 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator DUF4200 PF13863.6 EGC33005.1 - 8.9 6.7 18.3 1.2 9.5 3.2 3.6 2 1 0 3 3 3 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EGC33005.1 - 8.9 6.6 15.7 2.1 8.7 1.2 4.1 2 2 2 4 4 4 0 Bacterial protein of unknown function (DUF948) DUF3800 PF12686.7 EGC33005.1 - 9 7.0 8.3 77 3.9 8.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) BORCS7 PF16088.5 EGC33005.1 - 9.2 6.6 13.9 5.1 7.4 4.0 3.8 2 2 2 4 4 4 0 BLOC-1-related complex sub-unit 7 COG2 PF06148.11 EGC33005.1 - 9.4 6.3 13.6 5 7.2 4.9 3.3 2 2 1 3 3 3 0 COG (conserved oligomeric Golgi) complex component, COG2 zf-CCCH_2 PF14608.6 EGC33006.1 - 6.1e-24 83.6 80.6 2e-05 24.9 4.0 7.3 7 0 0 7 7 7 7 RNA-binding, Nab2-type zinc finger PWI PF01480.17 EGC33006.1 - 0.00013 22.2 0.1 0.00022 21.5 0.1 1.3 1 0 0 1 1 1 1 PWI domain zf-CCCH_4 PF18044.1 EGC33006.1 - 0.01 15.6 1.0 0.01 15.6 1.0 8.5 7 3 1 8 8 8 0 CCCH-type zinc finger SapB_1 PF05184.15 EGC33006.1 - 0.03 14.4 0.2 0.13 12.3 0.1 2.3 2 0 0 2 2 2 0 Saposin-like type B, region 1 zf_CCCH_4 PF18345.1 EGC33006.1 - 0.076 13.1 0.7 0.076 13.1 0.7 9.5 10 1 1 11 11 11 0 Zinc finger domain CBP_BcsG PF11658.8 EGC33006.1 - 0.19 10.1 0.9 0.27 9.6 0.9 1.1 1 0 0 1 1 1 0 Cellulose biosynthesis protein BcsG BRCT PF00533.26 EGC33007.1 - 2.7e-09 37.3 0.6 2.7e-09 37.3 0.6 2.6 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC33007.1 - 1.4e-07 31.8 0.4 1.4e-07 31.8 0.4 3.2 3 1 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain YL1 PF05764.13 EGC33007.1 - 0.001 19.3 28.0 0.001 19.3 28.0 3.5 3 1 0 3 3 3 1 YL1 nuclear protein Cpn60_TCP1 PF00118.24 EGC33008.1 - 9e-155 516.0 18.9 1e-154 515.8 18.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family SCAB_CC PF16712.5 EGC33008.1 - 0.037 13.9 0.4 0.037 13.9 0.4 2.0 2 0 0 2 2 2 0 Coiled-coil regions of plant-specific actin-binding protein Arm PF00514.23 EGC33011.1 - 7.1e-52 172.0 6.6 9.4e-12 44.6 0.0 8.1 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGC33011.1 - 2.3e-16 59.9 0.0 0.00057 20.3 0.0 5.3 4 1 1 5 5 5 4 HEAT-like repeat HEAT_2 PF13646.6 EGC33011.1 - 1.9e-15 57.0 0.0 9.1e-07 29.2 0.0 4.5 1 1 2 4 4 4 3 HEAT repeats HEAT PF02985.22 EGC33011.1 - 4.7e-15 54.4 0.1 0.00096 19.2 0.0 5.3 5 0 0 5 5 5 3 HEAT repeat RICTOR_V PF14668.6 EGC33011.1 - 5.7e-06 26.5 2.9 0.068 13.4 0.0 4.3 3 2 2 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Adaptin_N PF01602.20 EGC33011.1 - 7.2e-05 21.5 0.1 0.0049 15.5 0.0 2.3 1 1 1 2 2 2 2 Adaptin N terminal region Arm_2 PF04826.13 EGC33011.1 - 0.00077 19.0 0.1 1.1 8.7 0.0 2.4 2 0 0 2 2 2 2 Armadillo-like KAP PF05804.12 EGC33011.1 - 0.0061 14.8 0.1 0.02 13.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) Proteasom_PSMB PF10508.9 EGC33011.1 - 0.055 12.0 0.0 0.93 7.9 0.0 2.0 2 0 0 2 2 2 0 Proteasome non-ATPase 26S subunit HEAT_PBS PF03130.16 EGC33011.1 - 0.27 12.0 2.4 64 4.7 0.1 3.9 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat RNB PF00773.19 EGC33012.1 - 9.1e-102 340.7 0.0 9.1e-102 340.7 0.0 2.7 3 0 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 EGC33012.1 - 1.5e-20 73.0 0.0 3.8e-20 71.7 0.0 1.7 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) PIN_4 PF13638.6 EGC33012.1 - 9.3e-17 61.5 2.2 9.3e-17 61.5 2.2 2.9 2 0 0 2 2 2 1 PIN domain Rrp44_S1 PF17215.3 EGC33012.1 - 8.2e-13 48.1 0.2 2.5e-12 46.6 0.2 1.9 1 0 0 1 1 1 1 S1 domain Rrp44_CSD1 PF17216.3 EGC33012.1 - 9.9e-13 48.0 0.1 9.9e-13 48.0 0.1 2.4 2 1 1 3 3 3 1 Rrp44-like cold shock domain CSD2 PF17876.1 EGC33012.1 - 7.6e-10 38.8 0.7 1.1e-06 28.8 0.0 3.3 3 0 0 3 3 3 2 Cold shock domain Dis3l2_C_term PF17877.1 EGC33012.1 - 0.0071 16.6 0.1 0.0071 16.6 0.1 2.7 2 0 0 2 2 2 1 DIS3-like exonuclease 2 C terminal Isochorismatase PF00857.20 EGC33013.1 - 1.8e-35 122.7 0.0 2.2e-35 122.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF4183 PF13799.6 EGC33013.1 - 0.084 12.7 0.1 0.18 11.6 0.1 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4183) IBR PF01485.21 EGC33014.1 - 1.4e-21 76.5 42.1 8.7e-11 41.9 9.9 4.7 3 1 1 4 4 4 3 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGC33014.1 - 0.00018 21.3 2.0 0.00018 21.3 2.0 5.0 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC33014.1 - 0.00022 21.0 37.4 0.0034 17.2 6.4 4.4 4 0 0 4 4 4 3 Zinc finger, C3HC4 type (RING finger) zf-RING_14 PF17978.1 EGC33014.1 - 0.0011 19.3 2.4 0.0011 19.3 2.4 2.6 2 0 0 2 2 2 1 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EGC33014.1 - 0.0012 19.1 5.9 0.0012 19.1 5.9 4.8 3 2 2 5 5 5 1 Ring finger domain zf-C3HC4 PF00097.25 EGC33014.1 - 0.0031 17.4 7.4 0.0031 17.4 7.4 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC33014.1 - 0.014 15.1 2.8 0.049 13.4 2.8 2.0 1 0 0 1 1 1 0 RING-like zinc finger TIG PF01833.24 EGC33015.1 - 3.3e-08 33.5 12.1 7.1e-06 26.0 0.5 4.7 4 0 0 4 4 4 2 IPT/TIG domain EGF_Tenascin PF18720.1 EGC33015.1 - 0.0013 18.7 10.1 0.0038 17.2 10.1 1.8 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGC33015.1 - 0.0066 16.8 16.2 0.019 15.3 16.2 1.9 1 0 0 1 1 1 1 EGF-like domain Arm_3 PF16186.5 EGC33015.1 - 0.018 14.6 0.6 0.2 11.2 0.4 2.4 2 0 0 2 2 2 0 Atypical Arm repeat PH PF00169.29 EGC33015.1 - 0.22 12.0 3.0 15 6.2 0.3 3.3 3 0 0 3 3 3 0 PH domain SKG6 PF08693.10 EGC33015.1 - 1.8 8.1 5.0 4.2 6.9 5.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FNIP PF05725.12 EGC33016.1 - 1.3e-57 191.7 54.7 3.1e-11 43.2 3.6 8.3 4 2 5 9 9 9 9 FNIP Repeat LRR_5 PF13306.6 EGC33016.1 - 0.27 11.2 11.7 0.3 11.0 0.3 3.6 2 1 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Jnk-SapK_ap_N PF09744.9 EGC33018.1 - 0.18 12.0 33.2 0.21 11.8 33.2 1.0 1 0 0 1 1 1 0 JNK_SAPK-associated protein-1 PIN_12 PF16289.5 EGC33018.1 - 0.83 10.1 16.9 1 9.8 16.9 1.1 1 0 0 1 1 1 0 PIN domain CREPT PF16566.5 EGC33018.1 - 2.5 8.2 24.4 3.2 7.9 24.4 1.1 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour ABC2_membrane PF01061.24 EGC33020.1 - 7.4e-38 130.1 23.5 1.3e-37 129.3 23.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC33020.1 - 8e-26 91.2 0.1 1.7e-25 90.2 0.1 1.5 1 0 0 1 1 1 1 ABC transporter RsgA_GTPase PF03193.16 EGC33020.1 - 1.7e-05 24.8 0.8 3.5e-05 23.8 0.8 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_21 PF13304.6 EGC33020.1 - 6.7e-05 22.8 2.9 0.068 13.0 0.0 3.1 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC33020.1 - 0.00012 21.7 0.1 0.00029 20.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.6 EGC33020.1 - 0.00015 21.4 0.0 0.00029 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC33020.1 - 0.0006 20.2 0.0 0.0009 19.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC33020.1 - 0.00076 19.8 0.0 0.05 13.9 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGC33020.1 - 0.0034 17.9 0.0 0.0099 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGC33020.1 - 0.016 14.7 6.2 1 8.7 6.2 3.0 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain Cytidylate_kin PF02224.18 EGC33020.1 - 0.099 12.4 0.4 0.17 11.6 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase PDR_CDR PF06422.12 EGC33020.1 - 0.14 12.1 0.1 0.14 12.1 0.1 2.6 3 0 0 3 3 1 0 CDR ABC transporter AAA_28 PF13521.6 EGC33020.1 - 0.16 12.2 0.2 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC33020.1 - 0.17 11.8 0.1 0.37 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EGC33020.1 - 0.21 11.7 0.1 0.42 10.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain PHO4 PF01384.20 EGC33020.1 - 0.31 10.0 3.3 0.7 8.9 3.3 1.7 1 1 0 1 1 1 0 Phosphate transporter family AAA_23 PF13476.6 EGC33020.1 - 0.64 10.5 0.1 0.64 10.5 0.1 2.8 2 1 1 3 3 3 0 AAA domain ABC2_membrane PF01061.24 EGC33021.1 - 3.5e-36 124.6 24.8 3.5e-36 124.6 24.8 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC33021.1 - 2.3e-25 89.7 0.0 3.9e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC33021.1 - 2.5e-05 24.2 0.2 0.085 12.7 0.3 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC33021.1 - 0.00014 21.6 0.1 0.0003 20.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC33021.1 - 0.00026 20.9 0.5 0.00049 20.1 0.1 1.6 2 0 0 2 2 1 1 RsgA GTPase AAA_22 PF13401.6 EGC33021.1 - 0.00028 21.2 0.0 0.058 13.7 0.0 3.2 2 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGC33021.1 - 0.00042 19.9 0.1 0.0011 18.5 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC33021.1 - 0.0015 18.9 0.0 0.0028 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGC33021.1 - 0.0036 17.8 0.0 0.0075 16.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGC33021.1 - 0.0066 15.9 0.0 0.2 11.1 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain OppC_N PF12911.7 EGC33021.1 - 0.086 12.8 0.2 0.086 12.8 0.2 3.8 5 0 0 5 5 4 0 N-terminal TM domain of oligopeptide transport permease C PDR_CDR PF06422.12 EGC33021.1 - 0.087 12.7 0.2 0.087 12.7 0.2 3.0 3 0 0 3 3 2 0 CDR ABC transporter Cytidylate_kin PF02224.18 EGC33021.1 - 0.095 12.4 0.1 0.21 11.3 0.1 1.5 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 EGC33021.1 - 0.12 12.7 0.2 0.26 11.5 0.2 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC33021.1 - 0.16 11.8 0.1 0.36 10.7 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_33 PF13671.6 EGC33021.1 - 0.17 12.0 0.1 0.39 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC33021.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.5 2 1 1 3 3 3 0 AAA domain PHO4 PF01384.20 EGC33021.1 - 0.96 8.4 4.0 2.9 6.8 3.9 1.8 1 1 0 1 1 1 0 Phosphate transporter family ABC2_membrane_3 PF12698.7 EGC33021.1 - 5.8 5.9 27.7 3.2 6.8 19.1 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein Peptidase_M18 PF02127.15 EGC33023.1 - 5e-161 536.3 0.0 5.7e-161 536.1 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.14 EGC33023.1 - 3.2e-06 26.4 0.0 1.7e-05 24.0 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Actin PF00022.19 EGC33024.1 - 8e-67 225.6 0.0 1.5e-64 218.1 0.0 2.0 1 1 0 1 1 1 1 Actin FtsA PF14450.6 EGC33024.1 - 0.019 15.4 0.0 0.028 14.8 0.0 1.2 1 0 0 1 1 1 0 Cell division protein FtsA MreB_Mbl PF06723.13 EGC33024.1 - 0.13 11.1 0.0 4.1 6.1 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein FAD-oxidase_C PF02913.19 EGC33025.1 - 1.1e-54 185.8 0.0 1.6e-54 185.2 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.23 EGC33025.1 - 2.2e-37 127.9 0.0 3.9e-37 127.1 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Spore_III_AB PF09548.10 EGC33026.1 - 0.0018 18.4 0.8 0.0035 17.5 0.8 1.5 1 0 0 1 1 1 1 Stage III sporulation protein AB (spore_III_AB) DUF2207 PF09972.9 EGC33026.1 - 0.012 14.4 6.1 0.0095 14.7 1.7 2.2 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) PhoU PF01895.19 EGC33026.1 - 0.2 12.2 2.2 1 9.9 0.0 2.4 1 1 1 2 2 2 0 PhoU domain Spore_III_AB PF09548.10 EGC33027.1 - 0.033 14.3 0.4 0.083 13.0 0.4 1.7 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) PhoU PF01895.19 EGC33027.1 - 0.043 14.3 0.2 0.18 12.3 0.0 2.1 2 0 0 2 2 2 0 PhoU domain Het-C PF07217.11 EGC33027.1 - 0.28 9.7 1.7 0.54 8.7 1.7 1.3 1 0 0 1 1 1 0 Heterokaryon incompatibility protein Het-C 7TM-7TMR_HD PF07698.11 EGC33027.1 - 0.57 9.9 9.8 1.3 8.8 9.8 1.5 1 0 0 1 1 1 0 7TM receptor with intracellular HD hydrolase Spore_III_AB PF09548.10 EGC33028.1 - 0.044 13.9 0.3 0.094 12.8 0.3 1.5 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) Menin PF05053.13 EGC33030.1 - 0.11 10.9 5.3 0.12 10.7 5.3 1.2 1 0 0 1 1 1 0 Menin EVI2A PF05399.11 EGC33030.1 - 0.73 9.4 10.6 0.094 12.3 6.0 1.8 2 0 0 2 2 2 0 Ectropic viral integration site 2A protein (EVI2A) Sugar_tr PF00083.24 EGC33031.1 - 4.9e-94 315.7 42.6 8.4e-94 315.0 42.6 1.3 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGC33031.1 - 3.9e-45 154.3 58.5 1.4e-34 119.6 36.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGC33031.1 - 0.021 13.2 12.8 0.052 11.9 2.1 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Prefoldin_2 PF01920.20 EGC33032.1 - 6e-17 61.5 14.6 6e-17 61.5 14.6 1.7 1 1 1 2 2 2 1 Prefoldin subunit DUF4226 PF10774.9 EGC33032.1 - 0.03 14.6 2.9 0.091 13.1 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4226) DUF501 PF04417.12 EGC33032.1 - 0.064 13.1 4.3 0.18 11.6 0.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF501) DUF4164 PF13747.6 EGC33032.1 - 0.076 13.3 8.4 0.62 10.4 2.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Prefoldin_3 PF13758.6 EGC33032.1 - 0.08 13.0 6.1 0.12 12.4 6.1 1.3 1 0 0 1 1 1 0 Prefoldin subunit Nsp1_C PF05064.13 EGC33032.1 - 0.1 12.4 14.3 1.2 9.0 5.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region DUF1515 PF07439.11 EGC33032.1 - 0.42 10.7 2.4 7.4 6.6 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Spc24 PF08286.11 EGC33032.1 - 0.71 10.1 15.2 0.065 13.5 6.2 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2203 PF09969.9 EGC33032.1 - 1.2 9.9 7.7 0.92 10.2 2.2 2.1 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DMPK_coil PF08826.10 EGC33032.1 - 1.5 9.0 15.6 1.8 8.7 2.2 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like Prefoldin PF02996.17 EGC33032.1 - 2.1 8.3 14.3 18 5.2 14.3 2.5 1 1 0 1 1 1 0 Prefoldin subunit XhlA PF10779.9 EGC33032.1 - 2.1 8.6 11.0 0.76 10.0 2.8 2.4 2 0 0 2 2 2 0 Haemolysin XhlA MCU PF04678.13 EGC33032.1 - 2.7 8.0 7.3 4.9 7.2 5.5 1.8 1 1 1 2 2 2 0 Mitochondrial calcium uniporter DLP_helical PF18709.1 EGC33032.1 - 2.8 7.0 13.6 1.7 7.7 3.3 2.0 1 1 1 2 2 2 0 Dynamin-like helical domain Rotamase PF00639.21 EGC33032.1 - 3.2 8.8 7.5 1.8 9.6 0.5 2.3 1 1 1 2 2 2 0 PPIC-type PPIASE domain OmpH PF03938.14 EGC33032.1 - 3.4 8.0 21.8 60 4.0 21.8 2.0 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) NPV_P10 PF05531.12 EGC33032.1 - 3.4 8.2 11.2 2.9 8.4 2.7 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Mod_r PF07200.13 EGC33032.1 - 4.1 7.5 17.4 2.6 8.1 6.0 2.1 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein DUF3340 PF11818.8 EGC33032.1 - 5 7.3 16.0 24 5.1 16.0 1.9 1 1 0 1 1 1 0 C-terminal domain of tail specific protease (DUF3340) Fib_alpha PF08702.10 EGC33032.1 - 8 6.6 13.8 4.7 7.4 1.8 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Homeobox_KN PF05920.11 EGC33033.1 - 9.7e-05 22.2 0.5 0.0003 20.6 0.2 2.0 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EGC33033.1 - 0.017 14.9 1.0 0.047 13.5 1.0 1.8 1 0 0 1 1 1 0 Homeodomain Tir_receptor_C PF07489.11 EGC33033.1 - 6.2 6.7 8.2 12 5.8 8.2 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PDEase_II PF02112.15 EGC33034.1 - 1.8e-127 425.1 0.0 2.3e-127 424.8 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II SSV1_ORF_D-335 PF07935.11 EGC33035.1 - 0.058 13.7 2.1 11 6.4 0.1 3.6 3 0 0 3 3 3 0 ORF D-335-like protein AI-2E_transport PF01594.16 EGC33035.1 - 0.1 11.7 1.3 0.22 10.6 1.3 1.5 1 0 0 1 1 1 0 AI-2E family transporter Cor1 PF04803.12 EGC33035.1 - 5.8 7.1 10.2 2.9 8.1 4.6 2.6 2 0 0 2 2 2 0 Cor1/Xlr/Xmr conserved region Phage_lambda_P PF06992.11 EGC33036.1 - 0.038 13.7 1.8 0.055 13.2 0.3 2.0 2 0 0 2 2 2 0 Replication protein P Pepdidase_M14_N PF18027.1 EGC33036.1 - 1.6 9.1 7.1 1.1 9.6 1.6 2.7 2 0 0 2 2 2 0 Cytosolic carboxypeptidase N-terminal domain RNase_T PF00929.24 EGC33039.1 - 0.00015 22.3 0.3 0.00092 19.8 0.1 2.1 1 1 1 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGC33039.1 - 0.0013 18.5 0.0 0.0015 18.3 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF5051 PF16473.5 EGC33039.1 - 0.0013 18.7 0.1 0.023 14.7 0.1 2.2 1 1 2 3 3 3 1 3' exoribonuclease, RNase T-like RNase_H_2 PF13482.6 EGC33039.1 - 0.0098 15.9 0.0 0.012 15.6 0.0 1.3 1 0 0 1 1 1 1 RNase_H superfamily EcsB PF05975.12 EGC33040.1 - 0.063 12.1 3.4 0.078 11.8 3.4 1.0 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB TFIIA PF03153.13 EGC33041.1 - 0.0021 18.1 13.3 0.0025 17.9 13.3 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Kei1 PF08552.11 EGC33041.1 - 0.013 15.4 0.0 0.015 15.2 0.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 MAGE PF01454.19 EGC33041.1 - 0.027 14.2 1.4 0.044 13.5 1.4 1.3 1 0 0 1 1 1 0 MAGE family RasGEF_N PF00618.20 EGC33041.1 - 0.095 12.9 0.2 0.12 12.6 0.2 1.3 1 0 0 1 1 1 0 RasGEF N-terminal motif Peroxin-13_N PF04088.13 EGC33041.1 - 0.14 12.4 0.6 0.14 12.4 0.6 1.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region Presenilin PF01080.17 EGC33041.1 - 0.14 10.9 0.9 0.16 10.7 0.9 1.1 1 0 0 1 1 1 0 Presenilin SOG2 PF10428.9 EGC33041.1 - 0.15 11.2 3.6 0.14 11.4 3.6 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein Ndc1_Nup PF09531.10 EGC33041.1 - 0.22 10.2 8.8 0.28 9.8 8.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GET2 PF08690.10 EGC33041.1 - 0.67 9.6 12.3 1.6 8.3 12.2 1.7 1 1 0 1 1 1 0 GET complex subunit GET2 Suf PF05843.14 EGC33041.1 - 1 9.3 12.7 1.3 9.0 12.7 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF737 PF05300.11 EGC33041.1 - 5.4 7.3 15.2 7.3 6.9 15.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Zip PF02535.22 EGC33043.1 - 0.25 10.5 2.0 0.33 10.1 2.0 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Pro_dh PF01619.18 EGC33044.1 - 8.7e-68 229.0 0.0 1.2e-67 228.5 0.0 1.1 1 0 0 1 1 1 1 Proline dehydrogenase DEAD PF00270.29 EGC33045.1 - 1.8e-51 174.4 0.0 1.1e-50 171.8 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC33045.1 - 4.3e-30 104.3 0.0 2.7e-28 98.5 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC33045.1 - 0.0041 17.2 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit FumaraseC_C PF10415.9 EGC33046.1 - 0.13 12.7 0.1 1.3 9.4 0.0 2.5 2 1 0 2 2 2 0 Fumarase C C-terminus PH_11 PF15413.6 EGC33046.1 - 2.8 8.4 8.2 6.2 7.3 6.5 2.6 1 1 1 2 2 2 0 Pleckstrin homology domain PH PF00169.29 EGC33047.1 - 3.5e-12 46.8 0.1 1.8e-11 44.5 0.1 2.3 1 0 0 1 1 1 1 PH domain HA2 PF04408.23 EGC33048.1 - 2.1e-23 82.7 0.0 5.4e-23 81.3 0.0 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC33048.1 - 4.6e-17 62.1 0.0 1.8e-16 60.2 0.0 2.1 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGC33048.1 - 2e-12 47.4 0.0 5.5e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC33048.1 - 1.6e-07 31.2 0.1 4.2e-07 29.9 0.1 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGC33048.1 - 0.00015 22.0 0.3 0.0011 19.2 0.3 2.3 1 1 0 1 1 1 1 AAA domain ResIII PF04851.15 EGC33048.1 - 0.00032 20.8 0.0 0.21 11.6 0.0 2.6 2 0 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.9 EGC33048.1 - 0.00054 19.3 0.0 0.00099 18.4 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_19 PF13245.6 EGC33048.1 - 0.00059 20.2 0.1 0.0028 18.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGC33048.1 - 0.0015 18.2 0.0 0.0026 17.5 0.0 1.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGC33048.1 - 0.0031 17.3 0.0 2 8.1 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 EGC33048.1 - 0.0049 16.6 0.0 0.01 15.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain PhoH PF02562.16 EGC33048.1 - 0.0059 16.1 0.1 0.03 13.8 0.0 2.2 3 0 0 3 3 3 1 PhoH-like protein ABC_tran PF00005.27 EGC33048.1 - 0.011 16.3 0.0 0.07 13.6 0.0 2.3 2 0 0 2 2 2 0 ABC transporter Flavi_DEAD PF07652.14 EGC33048.1 - 0.053 13.5 0.0 0.2 11.6 0.0 2.0 2 0 0 2 2 1 0 Flavivirus DEAD domain AAA_7 PF12775.7 EGC33048.1 - 0.053 13.0 1.8 0.11 12.0 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region T2SSE PF00437.20 EGC33048.1 - 0.059 12.4 0.0 0.13 11.3 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.6 EGC33048.1 - 0.069 13.3 0.0 0.17 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGC33048.1 - 0.09 12.7 0.1 0.2 11.5 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase SRP54 PF00448.22 EGC33048.1 - 0.15 11.7 0.1 0.89 9.1 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_23 PF13476.6 EGC33048.1 - 0.39 11.2 0.1 0.39 11.2 0.1 2.8 2 1 1 3 3 3 0 AAA domain FNIP PF05725.12 EGC33049.1 - 2.6e-16 59.5 0.0 5.7e-14 52.0 0.0 2.0 1 1 1 2 2 2 2 FNIP Repeat FNIP PF05725.12 EGC33050.1 - 1e-05 25.6 38.5 0.0034 17.5 0.8 9.7 6 3 3 9 9 9 5 FNIP Repeat F-box-like PF12937.7 EGC33052.1 - 4.7e-06 26.4 1.6 9.8e-06 25.4 0.7 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGC33052.1 - 1.7e-05 24.6 0.5 1.7e-05 24.6 0.5 2.6 3 0 0 3 3 3 1 F-box domain Dapper PF15268.6 EGC33052.1 - 1.1 8.0 21.1 1.5 7.6 21.1 1.1 1 0 0 1 1 1 0 Dapper FNIP PF05725.12 EGC33053.1 - 4.5e-17 61.9 3.5 9e-08 32.2 0.3 5.0 2 2 3 6 6 6 5 FNIP Repeat Tcp10_C PF07202.13 EGC33053.1 - 0.17 11.8 0.1 5.5 6.9 0.0 2.4 2 1 0 2 2 2 0 T-complex protein 10 C-terminus RPAP2_Rtr1 PF04181.13 EGC33054.1 - 1.1e-19 70.4 2.0 2.9e-19 69.2 2.0 1.8 1 0 0 1 1 1 1 Rtr1/RPAP2 family Topoisom_bac PF01131.20 EGC33055.1 - 3.2e-106 355.8 0.4 4.3e-106 355.4 0.4 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.22 EGC33055.1 - 1.9e-17 63.4 0.1 4.4e-17 62.2 0.1 1.7 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.6 EGC33055.1 - 0.051 14.1 0.0 0.12 12.9 0.0 1.6 1 0 0 1 1 1 0 Toprim domain HypA PF01155.19 EGC33055.1 - 0.12 12.4 8.1 0.55 10.3 0.2 2.9 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA ketoacyl-synt PF00109.26 EGC33057.1 - 1.9e-62 211.1 0.0 2.9e-62 210.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC33057.1 - 6.3e-41 140.9 0.0 1.1e-40 140.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC33057.1 - 6.6e-32 110.0 0.0 4.2e-31 107.4 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC33057.1 - 1.6e-25 90.1 0.1 3.8e-25 88.8 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC33057.1 - 4e-22 78.8 0.0 6e-22 78.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC33057.1 - 4e-19 69.2 0.0 4e-19 69.2 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC33057.1 - 7.7e-18 65.0 0.3 3.1e-17 63.1 0.1 2.3 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC33057.1 - 6.5e-10 40.2 0.0 6.3e-09 37.0 0.0 2.5 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGC33057.1 - 2.2e-06 27.6 0.0 5.4e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EGC33057.1 - 4.6e-06 26.5 0.0 1.1e-05 25.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC33057.1 - 1.2e-05 25.9 0.0 6.7e-05 23.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EGC33057.1 - 1.6e-05 24.4 0.0 3.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EGC33057.1 - 0.0031 17.3 8.1 0.0036 17.1 0.0 4.4 4 0 0 4 4 4 1 Methyltransferase domain PP-binding PF00550.25 EGC33057.1 - 0.02 15.2 0.1 0.055 13.8 0.1 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site adh_short_C2 PF13561.6 EGC33057.1 - 0.21 11.1 0.2 0.43 10.1 0.2 1.4 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Cpn60_TCP1 PF00118.24 EGC33058.1 - 6.6e-80 269.1 15.5 1.1e-75 255.2 14.2 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Pkinase PF00069.25 EGC33059.1 - 3.6e-65 219.9 0.0 4.9e-65 219.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33059.1 - 2e-39 135.5 0.0 2.9e-39 134.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.6 EGC33059.1 - 2.6e-38 130.3 3.3 6.4e-38 129.0 3.3 1.7 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.6 EGC33059.1 - 3.3e-08 33.2 0.0 5.9e-08 32.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC33059.1 - 9.5e-06 24.8 2.6 1.5e-05 24.1 0.1 2.0 2 0 0 2 2 2 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGC33059.1 - 0.00012 20.9 0.2 0.00026 19.9 0.0 1.5 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGC33059.1 - 0.0016 18.4 0.0 0.029 14.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC33059.1 - 0.0017 18.0 0.2 0.0048 16.5 0.0 1.7 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.14 EGC33059.1 - 0.0089 15.4 0.0 0.015 14.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC33059.1 - 0.018 14.6 0.2 0.12 12.0 0.0 2.0 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 ArenaCapSnatch PF17296.2 EGC33059.1 - 0.065 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 Arenavirus cap snatching domain PH PF00169.29 EGC33059.1 - 0.13 12.8 1.1 0.52 10.8 0.2 2.3 2 0 0 2 2 2 0 PH domain Ribosomal_L29e PF01779.17 EGC33060.1 - 1.4e-15 57.4 10.0 1.4e-15 57.4 10.0 2.2 2 0 0 2 2 2 1 Ribosomal L29e protein family C2 PF00168.30 EGC33061.1 - 3.5e-17 62.6 0.1 7.8e-17 61.5 0.0 1.5 1 1 0 1 1 1 1 C2 domain C2 PF00168.30 EGC33062.1 - 5.3e-16 58.8 0.1 2.8e-15 56.5 0.1 1.9 1 1 1 2 2 2 1 C2 domain Ank_2 PF12796.7 EGC33063.1 - 0.00072 20.1 0.6 0.018 15.6 0.0 3.2 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Sdh_cyt PF01127.22 EGC33064.1 - 4e-20 72.1 0.3 5.1e-20 71.7 0.3 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit TNFR_c6 PF00020.18 EGC33065.1 - 2.9 8.4 8.4 18 5.8 0.3 3.2 3 0 0 3 3 3 0 TNFR/NGFR cysteine-rich region Sdh_cyt PF01127.22 EGC33066.1 - 3.1e-08 33.7 0.1 4.5e-08 33.2 0.1 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CUE PF02845.16 EGC33067.1 - 8.1e-15 54.2 0.8 5.8e-09 35.5 0.3 3.5 3 0 0 3 3 3 3 CUE domain UBA_4 PF14555.6 EGC33067.1 - 0.0049 16.7 0.0 3.7 7.5 0.0 2.8 3 0 0 3 3 3 2 UBA-like domain VIT PF08487.10 EGC33067.1 - 3.2 8.0 7.3 7.2 6.9 0.3 3.0 3 0 0 3 3 3 0 Vault protein inter-alpha-trypsin domain V-ATPase_G PF03179.15 EGC33068.1 - 2 9.0 7.1 0.099 13.2 1.0 2.0 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Exo5 PF09810.9 EGC33068.1 - 3.3 7.1 9.2 1.2 8.6 1.8 2.3 2 0 0 2 2 2 0 Exonuclease V - a 5' deoxyribonuclease DUF4857 PF16149.5 EGC33069.1 - 0.15 11.2 0.0 0.22 10.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4857) Metallophos PF00149.28 EGC33070.1 - 4.1e-06 27.5 1.7 1.8e-05 25.3 2.0 2.0 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGC33070.1 - 0.00072 20.1 0.3 0.0016 18.9 0.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain DUF973 PF06157.11 EGC33070.1 - 0.043 12.9 5.0 0.082 12.0 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) UPF0242 PF06785.11 EGC33070.1 - 0.087 12.9 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUF3611 PF12263.8 EGC33070.1 - 0.11 12.5 1.6 0.22 11.4 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3611) YMF19 PF02326.15 EGC33070.1 - 0.11 13.3 5.0 0.097 13.5 1.3 2.8 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF3309 PF11752.8 EGC33070.1 - 0.13 12.3 5.1 0.35 10.9 5.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) Dynein_AAA_lid PF17852.1 EGC33071.1 - 0.0081 16.3 0.1 0.022 14.9 0.1 1.8 1 1 0 1 1 1 1 Dynein heavy chain AAA lid domain GRAB PF10375.9 EGC33071.1 - 1.5 8.8 7.0 4.6 7.3 0.0 3.4 3 0 0 3 3 3 0 GRIP-related Arf-binding domain Tetraspanin PF00335.20 EGC33071.1 - 4.3 7.0 10.7 0.12 12.1 1.9 2.6 2 1 1 3 3 3 0 Tetraspanin family Pkinase_Tyr PF07714.17 EGC33072.1 - 1.8e-49 168.4 0.0 1.5e-47 162.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC33072.1 - 1.3e-41 142.7 0.0 1.9e-37 129.1 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.21 EGC33072.1 - 4.1e-33 113.3 0.1 3.2e-21 75.2 0.0 2.9 2 0 0 2 2 2 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) COR PF16095.5 EGC33072.1 - 1.7e-31 109.6 3.9 2.1e-24 86.4 1.6 2.7 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain LRR_4 PF12799.7 EGC33072.1 - 2.5e-14 53.1 38.2 1.6e-05 25.1 0.8 7.0 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC33072.1 - 3e-12 46.1 37.9 4.3e-08 32.8 14.3 5.9 4 2 2 6 6 5 3 Leucine rich repeat Roc PF08477.13 EGC33072.1 - 1.2e-10 41.6 0.3 4.5e-07 30.1 0.0 2.9 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase LRR_9 PF14580.6 EGC33072.1 - 0.00023 20.7 6.1 0.063 12.8 0.2 3.0 1 1 0 2 2 2 2 Leucine-rich repeat Ras PF00071.22 EGC33072.1 - 0.00081 19.0 0.2 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 1 Ras family UPF0182 PF03699.13 EGC33072.1 - 0.0059 14.8 0.3 0.0092 14.2 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0182) LRR_6 PF13516.6 EGC33072.1 - 0.031 14.3 19.8 0.83 9.9 0.1 6.2 5 0 0 5 5 5 0 Leucine Rich repeat DUF1404 PF07185.11 EGC33073.1 - 0.033 13.9 0.0 0.05 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) HTH_29 PF13551.6 EGC33075.1 - 7.7e-06 25.8 0.1 1.2e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EGC33075.1 - 1.2e-05 24.9 0.1 2.3e-05 24.0 0.1 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGC33075.1 - 9.3e-05 22.5 0.2 0.00014 21.9 0.2 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 EGC33075.1 - 0.00015 21.3 0.7 0.00022 20.7 0.7 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EGC33075.1 - 0.00036 20.2 0.3 0.00036 20.2 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 EGC33075.1 - 0.0053 17.3 0.1 0.43 11.2 0.1 2.2 1 1 1 2 2 2 1 Homeodomain-like domain HTH_36 PF13730.6 EGC33075.1 - 0.014 15.4 0.2 0.022 14.7 0.2 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.18 EGC33075.1 - 0.02 14.8 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain DUF603 PF04645.12 EGC33075.1 - 0.05 13.3 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_AsnC-type PF13404.6 EGC33075.1 - 0.066 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain TrmB PF01978.19 EGC33075.1 - 0.081 12.8 0.0 0.13 12.2 0.0 1.3 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Fe_dep_repress PF01325.19 EGC33075.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4_2 PF08281.12 EGC33075.1 - 0.091 12.4 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 EGC33075.1 - 0.11 12.0 0.0 0.22 11.1 0.0 1.6 1 1 0 1 1 1 0 Winged helix-turn-helix DNA-binding HTH_Crp_2 PF13545.6 EGC33075.1 - 0.13 12.3 0.1 0.16 12.0 0.1 1.2 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain DUF2057 PF09829.9 EGC33080.1 - 0.0012 19.0 0.1 5.6 7.1 0.0 3.6 4 0 0 4 4 4 2 Uncharacterized protein conserved in bacteria (DUF2057) Med20 PF08612.11 EGC33080.1 - 0.0027 17.1 0.3 0.72 9.2 0.0 2.5 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF2458 PF10454.9 EGC33080.1 - 0.08 12.6 0.5 3.7 7.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) DDE_3 PF13358.6 EGC33081.1 - 9.7e-09 35.1 0.7 2.3e-08 33.9 0.7 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease FNIP PF05725.12 EGC33082.1 - 3.6e-57 190.3 48.4 1.4e-09 37.9 0.1 10.2 4 2 6 10 10 10 10 FNIP Repeat TMEM154 PF15102.6 EGC33083.1 - 0.0028 17.6 0.0 0.0028 17.6 0.0 4.9 6 1 1 7 7 5 1 TMEM154 protein family DUF1129 PF06570.11 EGC33083.1 - 0.0066 16.0 0.5 0.0066 16.0 0.5 3.7 3 1 0 4 4 4 1 Protein of unknown function (DUF1129) UPF0029 PF01205.19 EGC33083.1 - 0.0093 16.3 1.5 25 5.3 0.0 5.2 5 1 1 6 6 6 0 Uncharacterized protein family UPF0029 Bax1-I PF01027.20 EGC33083.1 - 0.018 14.9 34.1 0.022 14.6 11.3 4.0 1 1 1 3 3 3 0 Inhibitor of apoptosis-promoting Bax1 MWFE PF15879.5 EGC33083.1 - 0.033 14.4 10.6 0.41 10.9 0.0 4.5 5 0 0 5 5 5 0 NADH-ubiquinone oxidoreductase MWFE subunit CbtA PF09490.10 EGC33083.1 - 0.064 13.0 0.6 1.7 8.3 0.0 3.3 1 1 3 4 4 4 0 Probable cobalt transporter subunit (CbtA) PRY PF13765.6 EGC33083.1 - 0.098 12.3 0.0 7.5 6.3 0.0 3.6 3 0 0 3 3 3 0 SPRY-associated domain Tagatose_6_P_K PF08013.11 EGC33083.1 - 0.1 11.3 0.0 8.7 4.9 0.0 3.0 4 0 0 4 4 4 0 Tagatose 6 phosphate kinase DUF2157 PF09925.9 EGC33083.1 - 0.5 10.2 18.0 4.2 7.1 0.7 4.1 4 1 0 4 4 4 0 Predicted membrane protein (DUF2157) AA_permease_2 PF13520.6 EGC33083.1 - 0.67 8.7 38.9 0.51 9.1 11.8 3.8 2 2 1 3 3 3 0 Amino acid permease DUF979 PF06166.12 EGC33083.1 - 0.87 8.7 10.4 0.24 10.5 0.5 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF979) Macoilin PF09726.9 EGC33085.1 - 0.64 8.5 6.0 0.63 8.5 6.0 1.0 1 0 0 1 1 1 0 Macoilin family Competence PF03772.16 EGC33086.1 - 0.038 13.3 3.0 0.047 13.0 3.0 1.1 1 0 0 1 1 1 0 Competence protein DUF2057 PF09829.9 EGC33088.1 - 0.003 17.8 0.0 5.8 7.0 0.0 3.2 3 0 0 3 3 3 2 Uncharacterized protein conserved in bacteria (DUF2057) MapZ_C2 PF18708.1 EGC33088.1 - 0.0061 16.8 0.3 0.25 11.7 0.1 2.5 2 0 0 2 2 2 1 MapZ extracellular C-terminal domain 2 DUF4271 PF14093.6 EGC33088.1 - 0.01 15.8 4.8 0.54 10.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) DUF2458 PF10454.9 EGC33088.1 - 0.015 14.9 0.5 3.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2458) Med20 PF08612.11 EGC33088.1 - 0.03 13.7 0.8 0.62 9.4 0.1 2.6 3 0 0 3 3 3 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Glyco_transf_36 PF06165.11 EGC33088.1 - 0.038 13.4 0.0 30 3.9 0.0 3.2 3 0 0 3 3 3 0 Glycosyltransferase family 36 YwpF PF14183.6 EGC33088.1 - 0.12 12.4 0.3 21 5.1 0.0 2.4 2 0 0 2 2 2 0 YwpF-like protein VID27 PF08553.10 EGC33088.1 - 0.19 10.7 4.3 0.75 8.8 0.1 3.2 2 2 1 3 3 3 0 VID27 C-terminal WD40-like domain Sas10_Utp3 PF04000.15 EGC33089.1 - 8.1e-20 71.3 0.3 8.1e-20 71.3 0.3 3.8 4 2 0 4 4 4 1 Sas10/Utp3/C1D family Sas10 PF09368.10 EGC33089.1 - 2.3e-15 56.8 13.0 2.3e-15 56.8 13.0 4.0 5 0 0 5 5 5 1 Sas10 C-terminal domain MSA-2c PF12238.8 EGC33090.1 - 0.49 10.4 7.4 0.58 10.1 1.6 2.9 3 0 0 3 3 3 0 Merozoite surface antigen 2c LRR_2 PF07723.13 EGC33090.1 - 6 7.7 6.7 94 3.9 0.0 4.3 4 0 0 4 4 4 0 Leucine Rich Repeat zf-AN1 PF01428.16 EGC33091.1 - 1.3e-17 63.7 32.5 4.4e-10 39.6 5.8 3.6 3 1 1 4 4 4 2 AN1-like Zinc finger Transp_Tc5_C PF04236.15 EGC33091.1 - 0.00079 19.7 4.9 0.00079 19.7 4.9 2.8 3 1 0 3 3 3 2 Tc5 transposase C-terminal domain DUF1272 PF06906.11 EGC33091.1 - 0.00085 19.4 3.0 0.00085 19.4 3.0 3.4 3 1 0 3 3 3 1 Protein of unknown function (DUF1272) PolC_DP2 PF03833.13 EGC33091.1 - 0.13 10.1 2.1 0.15 9.9 2.1 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 DUF3808 PF10300.9 EGC33092.1 - 1.4e-41 142.7 7.7 3.6e-41 141.4 7.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.6 EGC33092.1 - 1.4e-07 31.7 6.7 0.00012 22.3 0.4 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC33092.1 - 3e-07 30.0 11.4 0.14 12.4 0.9 6.7 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC33092.1 - 5.9e-06 26.7 0.0 0.26 11.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat RPN7 PF10602.9 EGC33092.1 - 3.1e-05 23.7 3.1 0.00016 21.5 0.6 3.1 3 0 0 3 3 3 1 26S proteasome subunit RPN7 TPR_21 PF09976.9 EGC33092.1 - 0.00028 20.7 4.6 0.11 12.2 0.0 4.0 3 2 2 5 5 5 1 Tetratricopeptide repeat-like domain TPR_1 PF00515.28 EGC33092.1 - 0.00045 19.9 11.0 1.7 8.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC33092.1 - 0.00046 20.4 9.1 0.59 10.4 0.1 4.9 4 2 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC33092.1 - 0.0012 19.3 6.9 0.46 11.2 0.0 5.5 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC33092.1 - 0.0043 17.7 0.0 0.58 11.1 0.0 3.9 4 2 1 5 5 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC33092.1 - 0.0049 17.5 0.0 1.9 9.2 0.0 4.1 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC33092.1 - 0.0076 16.4 14.7 2.3 8.6 1.7 6.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC33092.1 - 0.036 14.0 0.3 4.9 7.2 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGC33092.1 - 0.061 13.7 0.1 6 7.3 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC33092.1 - 0.47 10.9 3.0 29 5.4 0.1 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat YebO PF13974.6 EGC33093.1 - 0.026 14.6 0.6 0.052 13.6 0.6 1.5 1 0 0 1 1 1 0 YebO-like protein DUF2808 PF10989.8 EGC33093.1 - 0.026 14.5 0.1 0.082 12.9 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2808) Insulin_TMD PF17870.1 EGC33093.1 - 0.039 14.0 3.3 0.042 13.9 1.2 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment EGF_2 PF07974.13 EGC33093.1 - 0.12 12.7 13.6 0.083 13.3 11.4 1.8 2 0 0 2 2 2 0 EGF-like domain Glyco_hydro_31 PF01055.26 EGC33095.1 - 3.6e-139 464.7 8.5 6.7e-139 463.9 8.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.6 EGC33095.1 - 7.7e-24 83.8 0.5 3.5e-23 81.7 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like DUF5110 PF17137.4 EGC33095.1 - 7.2e-07 29.4 1.1 2e-06 28.0 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF5110) DUF2846 PF11008.8 EGC33095.1 - 0.067 13.2 0.2 0.47 10.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2846) ACI44 PF15270.6 EGC33097.1 - 0.056 13.6 5.5 0.29 11.3 0.4 2.6 2 1 1 3 3 3 0 Metallo-carboxypeptidase inhibitor Nodulin_late PF07127.11 EGC33097.1 - 0.13 12.6 5.4 1 9.7 0.3 2.2 2 0 0 2 2 2 0 Late nodulin protein RD3 PF14473.6 EGC33098.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.1 1 0 0 1 1 1 0 RD3 protein CLIP PF12032.8 EGC33098.1 - 0.03 14.6 2.5 0.25 11.7 1.7 2.3 1 1 1 2 2 2 0 Regulatory CLIP domain of proteinases HHH_4 PF14490.6 EGC33098.1 - 0.036 14.1 0.0 0.058 13.4 0.0 1.3 1 0 0 1 1 1 0 Helix-hairpin-helix containing domain LsmAD PF06741.13 EGC33099.1 - 7.9e-23 80.8 4.5 7.9e-23 80.8 4.5 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.6 EGC33099.1 - 1.1e-16 60.7 0.1 3.7e-16 59.0 0.1 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain PAM2 PF07145.15 EGC33099.1 - 5.9e-06 25.6 0.8 2.5e-05 23.6 0.8 2.2 1 0 0 1 1 1 1 Ataxin-2 C-terminal region KH_8 PF17903.1 EGC33099.1 - 0.14 12.3 0.2 0.49 10.5 0.0 1.9 2 0 0 2 2 2 0 Krr1 KH1 domain TRAP_alpha PF03896.16 EGC33099.1 - 6.6 5.8 8.6 13 4.9 8.6 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Itfg2 PF15907.5 EGC33100.1 - 8e-50 169.8 20.7 2.3e-18 66.4 1.5 6.5 5 1 0 6 6 6 6 Integrin-alpha FG-GAP repeat-containing protein 2 BBS2_Mid PF14783.6 EGC33100.1 - 2.9e-09 36.9 1.3 0.0055 16.7 0.1 3.6 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 EGC33100.1 - 5.3e-06 26.5 3.4 0.015 15.4 0.3 2.6 2 0 0 2 2 2 2 FG-GAP repeat BBS1 PF14779.6 EGC33100.1 - 0.0005 19.6 1.5 0.09 12.2 0.0 3.2 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 1 PliI PF16743.5 EGC33100.1 - 0.083 12.6 0.5 2.7 7.8 0.0 3.2 4 0 0 4 4 4 0 Periplasmic lysozyme inhibitor of I-type lysozyme Trypan_PARP PF05887.11 EGC33101.1 - 2e-07 31.0 132.3 3.7e-05 23.7 67.3 5.4 2 1 4 6 6 6 4 Procyclic acidic repetitive protein (PARP) YqzL PF14006.6 EGC33101.1 - 0.17 12.3 0.0 0.17 12.3 0.0 3.8 3 0 0 3 3 3 0 YqzL-like protein DUF4818 PF16089.5 EGC33102.1 - 1.4e-06 28.7 18.8 4.2 7.9 0.2 6.6 4 2 2 6 6 6 5 Domain of unknown function (DUF4818) ATPase_gene1 PF09527.10 EGC33102.1 - 4.9e-06 26.6 8.8 7.4 6.8 0.1 6.1 6 0 0 6 6 6 1 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter Cyt_bd_oxida_II PF02322.15 EGC33102.1 - 1.5e-05 24.5 16.5 0.012 15.0 6.5 3.4 1 1 1 3 3 3 2 Cytochrome bd terminal oxidase subunit II UPF0029 PF01205.19 EGC33102.1 - 0.00023 21.4 0.2 10 6.5 0.0 5.9 6 1 1 7 7 7 1 Uncharacterized protein family UPF0029 DUF2798 PF11391.8 EGC33102.1 - 0.0019 18.2 42.9 0.64 10.1 1.8 6.7 3 2 4 7 7 7 4 Protein of unknown function (DUF2798) L6_membrane PF05805.12 EGC33102.1 - 0.048 13.2 25.5 0.48 10.0 0.9 5.7 2 2 3 6 6 6 0 L6 membrane protein Rax2 PF12768.7 EGC33102.1 - 0.39 10.1 5.4 56 3.1 1.8 4.6 4 1 0 4 4 4 0 Cortical protein marker for cell polarity SpoIIM PF01944.17 EGC33102.1 - 0.89 9.6 26.3 0.55 10.3 1.0 4.9 2 2 1 3 3 3 0 Stage II sporulation protein M SIT PF15330.6 EGC33102.1 - 3.6 8.1 13.5 1e+02 3.4 0.0 5.7 6 0 0 6 6 6 0 SHP2-interacting transmembrane adaptor protein, SIT DUF4271 PF14093.6 EGC33102.1 - 6.9 6.5 21.3 0.41 10.5 5.0 3.4 2 2 1 3 3 3 0 Domain of unknown function (DUF4271) Fucokinase PF07959.12 EGC33103.1 - 1.2e-84 284.6 0.0 1.9e-84 284.0 0.0 1.3 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.26 EGC33103.1 - 1e-07 32.1 0.3 2.2e-07 31.0 0.3 1.6 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGC33103.1 - 0.0036 17.6 0.0 0.0095 16.3 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Phage_Gp15 PF06854.11 EGC33104.1 - 0.0078 16.2 2.9 0.0085 16.1 2.9 1.1 1 0 0 1 1 1 1 Bacteriophage Gp15 protein DUF2924 PF11149.8 EGC33104.1 - 0.097 13.1 0.1 0.11 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) BSD PF03909.17 EGC33104.1 - 0.18 11.8 2.1 0.38 10.8 2.1 1.5 1 0 0 1 1 1 0 BSD domain Sen15 PF09631.10 EGC33106.1 - 7.7e-19 67.9 0.7 1.2e-18 67.2 0.2 1.5 2 0 0 2 2 2 1 Sen15 protein C2 PF00168.30 EGC33108.1 - 9.7e-12 45.1 0.4 7.4e-09 35.8 0.2 2.4 2 0 0 2 2 2 2 C2 domain WW PF00397.26 EGC33108.1 - 5.8e-10 39.1 1.8 1.6e-09 37.7 1.8 1.9 1 0 0 1 1 1 1 WW domain An_peroxidase PF03098.15 EGC33109.1 - 1.1e-130 436.8 0.0 1.3e-130 436.5 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Coiled PF05710.12 EGC33111.1 - 0.098 13.5 6.8 0.1 13.5 6.8 1.1 1 0 0 1 1 1 0 Coiled coil Peptidase_M14 PF00246.24 EGC33112.1 - 2e-69 234.6 0.0 2.4e-69 234.3 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.6 EGC33112.1 - 1.9e-06 28.0 0.1 3e-06 27.4 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.14 EGC33112.1 - 4.6e-06 25.9 0.0 9.6e-06 24.9 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family CarbopepD_reg_2 PF13715.6 EGC33112.1 - 1.7e-05 24.7 0.1 3.1e-05 23.9 0.1 1.5 1 0 0 1 1 1 1 CarboxypepD_reg-like domain DUF2817 PF10994.8 EGC33112.1 - 0.00025 20.6 0.1 0.00037 20.0 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) adh_short PF00106.25 EGC33113.1 - 4.9e-29 101.2 0.0 5.5e-28 97.8 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33113.1 - 2.7e-16 59.8 0.0 4.6e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33113.1 - 0.0001 22.3 0.0 0.00016 21.6 0.0 1.3 1 0 0 1 1 1 1 KR domain PA14 PF07691.12 EGC33115.1 - 2e-11 43.9 0.2 3.2e-11 43.2 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33115.1 - 0.0042 17.0 10.1 0.0042 17.0 10.1 15.0 13 4 2 15 15 15 7 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC33116.1 - 2.4e-12 46.9 1.0 4.5e-12 46.0 1.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33116.1 - 0.0032 17.3 9.7 0.0032 17.3 9.7 14.9 15 2 1 16 16 16 5 Dictyostelium (slime mold) repeat Vac14_Fig4_bd PF11916.8 EGC33117.1 - 5.9e-72 241.1 6.9 1.8e-71 239.5 6.9 1.9 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.7 EGC33117.1 - 2.2e-44 150.0 0.9 1.1e-39 134.9 0.0 4.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.22 EGC33117.1 - 1.8e-09 37.1 3.3 0.024 14.9 0.0 6.3 7 0 0 7 7 6 2 HEAT repeat HEAT_2 PF13646.6 EGC33117.1 - 2.2e-05 24.7 0.0 3.3 8.2 0.0 4.8 5 0 0 5 5 5 2 HEAT repeats HEAT_EZ PF13513.6 EGC33117.1 - 0.00015 22.1 0.0 2.6 8.6 0.0 3.8 3 0 0 3 3 3 2 HEAT-like repeat CLASP_N PF12348.8 EGC33117.1 - 0.0012 18.4 7.2 5.3 6.5 0.1 5.2 3 2 1 5 5 5 2 CLASP N terminal Cnd1 PF12717.7 EGC33117.1 - 0.015 15.4 11.0 1.3 9.1 0.2 4.5 4 1 1 5 5 5 0 non-SMC mitotic condensation complex subunit 1 DUF3437 PF11919.8 EGC33117.1 - 0.019 14.8 0.0 0.13 12.2 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Arm PF00514.23 EGC33117.1 - 0.02 14.9 0.0 6.8 6.9 0.0 4.0 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat RasGEF_N_2 PF14663.6 EGC33117.1 - 0.17 12.3 5.4 17 5.9 0.1 3.8 4 0 0 4 4 4 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain RTP1_C1 PF10363.9 EGC33117.1 - 0.32 11.2 2.4 5.8 7.1 0.0 3.6 3 1 0 3 3 3 0 Required for nuclear transport of RNA pol II C-terminus 1 Pkinase PF00069.25 EGC33119.1 - 1.1e-21 77.4 4.3 1.1e-21 77.4 4.3 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33119.1 - 8.4e-11 41.6 1.0 1.9e-10 40.5 1.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC33119.1 - 9.1e-06 24.7 0.6 1.7e-05 23.8 0.6 1.4 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC33119.1 - 0.014 14.8 0.0 0.024 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC33119.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGC33119.1 - 0.091 12.7 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.25 EGC33120.1 - 2.5e-14 53.3 4.0 7e-13 48.5 4.0 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33120.1 - 7e-06 25.5 0.2 5.3e-05 22.6 0.0 1.9 1 1 0 2 2 2 1 Protein tyrosine kinase Gcd10p PF04189.13 EGC33120.1 - 0.046 12.8 2.7 0.03 13.5 1.2 1.4 1 1 0 1 1 1 0 Gcd10p family DUF3391 PF11871.8 EGC33121.1 - 0.087 13.4 1.5 0.23 12.0 1.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3391) VTC PF09359.10 EGC33123.1 - 0.027 13.9 1.3 0.032 13.6 1.3 1.1 1 0 0 1 1 1 0 VTC domain Ten1_2 PF15490.6 EGC33125.1 - 7.2e-14 51.5 0.3 1.5e-13 50.5 0.3 1.5 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit DUF2971 PF11185.8 EGC33125.1 - 0.075 14.2 1.6 0.15 13.2 1.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2971) EGF_2 PF07974.13 EGC33126.1 - 0.0069 16.7 3.6 0.016 15.5 3.6 1.7 1 1 0 1 1 1 1 EGF-like domain PseudoU_synth_1 PF01416.20 EGC33127.1 - 2e-31 108.7 0.0 5e-29 100.9 0.0 2.4 2 0 0 2 2 2 2 tRNA pseudouridine synthase Peroxin-13_N PF04088.13 EGC33127.1 - 1.5 9.1 8.3 2.3 8.5 0.2 3.0 3 0 0 3 3 3 0 Peroxin 13, N-terminal region UTP25 PF06862.12 EGC33128.1 - 1.3e-169 564.9 19.9 2.3e-169 564.2 19.9 1.4 1 0 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 DEAD PF00270.29 EGC33128.1 - 0.00029 20.6 0.8 0.3 10.8 0.8 2.8 1 1 0 1 1 1 1 DEAD/DEAH box helicase Methyltransf_25 PF13649.6 EGC33129.1 - 3.1e-08 34.2 0.0 1.1e-07 32.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGC33129.1 - 7.1e-08 32.2 0.0 1.2e-07 31.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_11 PF08241.12 EGC33129.1 - 2.4e-07 31.3 0.0 6.2e-07 30.0 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC33129.1 - 2.5e-07 30.6 0.1 5.4e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 EGC33129.1 - 6.6e-07 29.3 0.0 1.2e-06 28.5 0.0 1.4 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase MTS PF05175.14 EGC33129.1 - 4.8e-06 26.2 0.1 1.9e-05 24.3 0.0 1.9 2 1 1 3 3 3 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EGC33129.1 - 2.7e-05 23.9 0.2 0.00011 21.9 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.12 EGC33129.1 - 0.00014 22.5 0.0 0.00047 20.9 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC33129.1 - 0.00024 21.0 0.1 0.00077 19.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC33129.1 - 0.00042 20.3 0.0 0.00077 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC33129.1 - 0.0017 17.3 0.0 0.0031 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PRMT5_C PF17286.2 EGC33129.1 - 0.0059 16.5 0.9 0.0095 15.8 0.9 1.4 1 0 0 1 1 1 1 PRMT5 oligomerisation domain Rsm22 PF09243.10 EGC33129.1 - 0.0093 15.3 0.0 0.014 14.7 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_32 PF13679.6 EGC33129.1 - 0.069 13.1 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain ZYG-11_interact PF05884.12 EGC33130.1 - 0.041 13.3 0.3 0.067 12.6 0.2 1.3 1 1 0 1 1 1 0 Interactor of ZYG-11 Methyltr_RsmB-F PF01189.17 EGC33131.1 - 1.2e-24 87.1 0.0 2.1e-24 86.3 0.0 1.4 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGC33131.1 - 0.00087 19.4 0.0 0.0015 18.7 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase NAPRTase_C PF17956.1 EGC33132.1 - 5.2e-37 126.7 0.2 1.3e-36 125.4 0.1 1.8 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase C-terminal domain NAPRTase_N PF17767.1 EGC33132.1 - 3.9e-36 124.2 0.1 1.9e-35 121.9 0.0 2.1 2 0 0 2 2 2 1 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain NAPRTase PF04095.16 EGC33132.1 - 2.2e-06 27.5 0.0 0.00073 19.2 0.0 2.2 2 0 0 2 2 2 2 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_21 PF05050.12 EGC33132.1 - 0.15 12.1 0.2 8.1 6.4 0.0 2.6 2 0 0 2 2 2 0 Methyltransferase FkbM domain Erf4 PF10256.9 EGC33133.1 - 5.7e-05 23.2 0.1 0.00056 20.0 0.0 2.1 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family PUNUT PF16913.5 EGC33133.1 - 0.043 13.1 0.0 0.053 12.7 0.0 1.1 1 0 0 1 1 1 0 Purine nucleobase transmembrane transport EphA2_TM PF14575.6 EGC33133.1 - 0.086 13.7 0.0 0.37 11.7 0.0 1.9 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Secretin_N_2 PF07655.13 EGC33134.1 - 6.8 7.3 12.5 2.2 8.9 2.3 2.7 2 0 0 2 2 2 0 Secretin N-terminal domain DHFR_1 PF00186.19 EGC33135.1 - 7.4e-34 116.8 0.3 1.5e-32 112.5 0.3 2.0 1 1 0 1 1 1 1 Dihydrofolate reductase SBDS PF01172.18 EGC33135.1 - 0.078 13.1 0.1 2.5 8.3 0.1 2.4 1 1 1 2 2 2 0 Shwachman-Bodian-Diamond syndrome (SBDS) protein Ank_4 PF13637.6 EGC33136.1 - 2.4e-23 82.2 0.3 3.3e-07 30.7 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC33136.1 - 1.4e-22 80.1 2.1 1.7e-14 54.1 1.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC33136.1 - 7e-22 77.2 0.3 5.3e-10 39.4 0.0 3.3 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC33136.1 - 5.1e-13 48.8 0.4 0.00087 19.6 0.1 3.8 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.6 EGC33136.1 - 5.1e-13 47.9 0.2 0.00011 22.4 0.0 4.0 4 0 0 4 4 4 2 Ankyrin repeat Mito_carr PF00153.27 EGC33137.1 - 1.5e-10 40.9 0.1 6.2e-05 22.8 0.0 2.6 1 1 1 2 2 2 2 Mitochondrial carrier protein LAP1C PF05609.12 EGC33137.1 - 3.6 6.6 24.9 0.42 9.7 20.3 1.7 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 EGC33137.1 - 5 5.6 24.1 7.4 5.0 24.1 1.4 1 0 0 1 1 1 0 Macoilin family zf-C2HE PF16278.5 EGC33139.1 - 0.0035 17.7 0.0 0.016 15.6 0.0 2.2 1 0 0 1 1 1 1 C2HE / C2H2 / C2HC zinc-binding finger zf-C2H2 PF00096.26 EGC33139.1 - 0.11 13.0 2.7 5.6 7.6 0.1 2.8 2 0 0 2 2 2 0 Zinc finger, C2H2 type Proteasome PF00227.26 EGC33140.1 - 2.7e-53 180.3 0.0 3.6e-53 179.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC33140.1 - 9.4e-14 50.8 0.0 1.8e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature MoaE PF02391.17 EGC33140.1 - 0.013 15.7 0.1 0.024 14.9 0.1 1.4 1 0 0 1 1 1 0 MoaE protein F-box-like PF12937.7 EGC33141.1 - 1.7e-08 34.2 1.6 3.2e-08 33.3 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGC33141.1 - 4.2e-07 29.7 0.1 4.2e-07 29.7 0.1 3.3 4 0 0 4 4 4 1 F-box domain F-box-like_2 PF13013.6 EGC33141.1 - 0.0011 19.0 1.0 0.11 12.4 0.2 3.3 2 1 0 2 2 2 1 F-box-like domain F-box_4 PF15966.5 EGC33141.1 - 0.014 15.2 0.0 0.014 15.2 0.0 3.4 5 0 0 5 5 5 0 F-box STAS PF01740.21 EGC33141.1 - 0.021 14.4 0.6 1 9.0 0.2 2.9 3 0 0 3 3 3 0 STAS domain NOA36 PF06524.12 EGC33141.1 - 0.1 11.9 7.4 0.18 11.1 7.4 1.4 1 0 0 1 1 1 0 NOA36 protein Presenilin PF01080.17 EGC33141.1 - 4.9 5.8 15.4 7.7 5.2 15.4 1.3 1 0 0 1 1 1 0 Presenilin PRP1_N PF06424.12 EGC33141.1 - 8.3 6.8 13.1 18 5.7 13.1 1.5 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Erf4 PF10256.9 EGC33143.1 - 3.6e-05 23.8 0.3 0.00022 21.3 0.3 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF5367 PF17329.2 EGC33143.1 - 0.032 14.4 0.4 0.057 13.6 0.4 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5367) DNA_pol_alpha_N PF12254.8 EGC33143.1 - 0.035 14.2 0.6 0.14 12.2 0.2 2.0 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal DUF5392 PF17370.2 EGC33143.1 - 0.08 13.0 0.5 7.8 6.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5392) CSN8_PSD8_EIF3K PF10075.9 EGC33144.1 - 7.9e-24 84.3 1.2 7.9e-24 84.3 1.2 1.6 2 0 0 2 2 2 1 CSN8/PSMD8/EIF3K family PCI PF01399.27 EGC33144.1 - 0.032 14.8 0.1 0.071 13.6 0.1 1.7 1 0 0 1 1 1 0 PCI domain Propeptide_C1 PF08127.13 EGC33144.1 - 0.087 12.7 0.7 0.21 11.5 0.3 1.9 2 0 0 2 2 2 0 Peptidase family C1 propeptide DIL PF01843.19 EGC33145.1 - 4.1e-05 23.8 0.1 9.9e-05 22.6 0.1 1.6 2 0 0 2 2 2 1 DIL domain LRIF1 PF15741.5 EGC33147.1 - 0.051 12.1 1.0 0.061 11.9 1.0 1.0 1 0 0 1 1 1 0 Ligand-dependent nuclear receptor-interacting factor 1 Lipase_3 PF01764.25 EGC33148.1 - 5e-34 117.2 0.0 7.3e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGC33148.1 - 3.8e-07 29.9 0.0 1.2e-06 28.3 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGC33148.1 - 0.0095 16.6 0.0 0.013 16.1 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.7 EGC33148.1 - 0.16 11.7 0.0 0.33 10.7 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family zf-Di19 PF05605.12 EGC33148.1 - 0.25 11.7 0.9 15 5.9 0.0 2.9 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Nup96 PF12110.8 EGC33149.1 - 4.4e-76 255.8 0.1 4.4e-76 255.8 0.1 1.7 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.14 EGC33149.1 - 6.1e-40 136.8 0.0 6.1e-40 136.8 0.0 2.8 3 0 0 3 3 3 1 Nucleoporin autopeptidase TFIIA PF03153.13 EGC33149.1 - 0.0024 18.0 29.7 0.07 13.1 16.4 2.3 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit Urb2 PF10441.9 EGC33151.1 - 8.8e-13 48.7 0.1 8.8e-13 48.7 0.1 3.5 4 0 0 4 4 4 1 Urb2/Npa2 family Na_trans_assoc PF06512.13 EGC33151.1 - 0.00075 19.8 0.0 0.12 12.7 0.0 2.8 1 1 0 1 1 1 1 Sodium ion transport-associated DRY_EERY PF09750.9 EGC33151.1 - 3.7 7.8 8.5 3.2 8.0 1.2 2.7 2 0 0 2 2 2 0 Alternative splicing regulator CN_hydrolase PF00795.22 EGC33152.1 - 9.1e-39 133.4 0.0 1.4e-38 132.8 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase NAD_synthase PF02540.17 EGC33152.1 - 1.1e-23 83.7 0.0 2.4e-23 82.5 0.0 1.5 1 0 0 1 1 1 1 NAD synthase Acetyltransf_2 PF00797.17 EGC33153.1 - 1e-18 68.1 1.8 1.4e-18 67.6 1.8 1.1 1 0 0 1 1 1 1 N-acetyltransferase EDR1 PF14381.6 EGC33153.1 - 0.017 14.8 0.0 0.039 13.7 0.0 1.6 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 TGT PF01702.18 EGC33154.1 - 1.3e-31 110.0 0.0 1.7e-31 109.7 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase KH_7 PF17214.3 EGC33154.1 - 0.049 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 KH domain Ost4 PF10215.9 EGC33154.1 - 0.14 12.0 1.5 0.35 10.7 1.5 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase TGT PF01702.18 EGC33155.1 - 7.3e-49 166.8 0.0 8.1e-49 166.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Granulin PF00396.18 EGC33156.1 - 1.3e-10 41.4 25.8 1.6e-10 41.1 21.1 2.1 2 0 0 2 2 2 2 Granulin HEAT PF02985.22 EGC33157.1 - 7.2e-45 147.2 24.1 0.0004 20.4 0.1 13.8 15 0 0 15 15 15 10 HEAT repeat HEAT_2 PF13646.6 EGC33157.1 - 1.2e-35 121.7 2.2 3.5e-10 40.1 0.0 6.7 3 2 3 6 6 6 6 HEAT repeats Vac14_Fab1_bd PF12755.7 EGC33157.1 - 2.1e-11 44.3 1.3 0.095 13.3 0.0 7.1 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.20 EGC33157.1 - 2.6e-10 39.5 7.8 0.037 12.6 0.0 3.5 1 1 0 2 2 2 2 Adaptin N terminal region Cnd1 PF12717.7 EGC33157.1 - 4.2e-10 39.9 8.6 0.00047 20.2 1.7 4.9 2 1 2 4 4 4 4 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGC33157.1 - 6.7e-10 39.3 12.1 0.00076 19.9 0.0 7.5 7 2 2 9 9 9 2 HEAT-like repeat CLASP_N PF12348.8 EGC33157.1 - 1.9e-07 30.9 0.5 0.21 11.1 0.0 5.0 2 1 2 5 5 5 1 CLASP N terminal RTP1_C1 PF10363.9 EGC33157.1 - 2.9e-05 24.2 5.8 0.12 12.5 0.5 4.8 4 2 2 6 6 6 3 Required for nuclear transport of RNA pol II C-terminus 1 Arm PF00514.23 EGC33157.1 - 0.0019 18.2 1.1 8.6 6.6 0.0 5.7 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 EGC33157.1 - 0.0061 15.7 0.2 0.023 13.8 0.2 2.1 1 0 0 1 1 1 1 Interferon-related developmental regulator (IFRD) DEAD PF00270.29 EGC33158.1 - 4.1e-50 170.0 0.0 6.7e-50 169.3 0.0 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC33158.1 - 1.5e-30 105.8 0.0 1.2e-29 102.9 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC33158.1 - 2.7e-05 24.3 0.0 6e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGC33158.1 - 0.73 9.1 2.4 0.48 9.7 0.1 1.8 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit FNIP PF05725.12 EGC33160.1 - 3.5e-99 324.8 27.7 3.5e-14 52.7 1.6 8.2 7 1 1 8 8 8 8 FNIP Repeat MCM_OB PF17207.3 EGC33160.1 - 0.00041 20.2 0.1 1.2e+02 2.6 0.0 5.8 2 2 5 8 8 8 0 MCM OB domain Phage_min_tail PF05939.13 EGC33160.1 - 0.00054 20.3 0.2 73 3.8 0.0 6.3 1 1 4 7 7 7 0 Phage minor tail protein DUF3215 PF11503.8 EGC33160.1 - 2.4 8.1 3.5 22 5.0 0.0 4.2 6 0 0 6 6 6 0 Protein of unknown function (DUF3215) GLTSCR1 PF15249.6 EGC33161.1 - 1.6e-06 28.5 0.9 1.6e-06 28.5 0.9 3.9 3 0 0 3 3 3 1 Conserved region of unknown function on GLTSCR protein Virul_fac_BrkB PF03631.15 EGC33162.1 - 0.0014 18.3 2.7 0.0014 18.3 2.7 2.4 2 0 0 2 2 2 1 Virulence factor BrkB DUF805 PF05656.14 EGC33162.1 - 0.073 13.5 0.3 0.073 13.5 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF805) HRG PF16954.5 EGC33162.1 - 0.52 10.8 0.1 0.52 10.8 0.1 4.0 4 0 0 4 4 4 0 Haem-transporter, endosomal/lysosomal, haem-responsive gene Vpu PF00558.19 EGC33162.1 - 1.2 9.0 5.3 2.8 7.8 0.1 3.1 3 0 0 3 3 3 0 Vpu protein UCR_UQCRX_QCR9 PF05365.12 EGC33164.1 - 3.9e-17 61.9 3.3 4.3e-17 61.8 3.3 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like E3_UFM1_ligase PF09743.9 EGC33165.1 - 1.1e-91 307.3 14.0 1.1e-91 307.3 14.0 2.0 2 0 0 2 2 2 1 E3 UFM1-protein ligase 1 HTH_9 PF08221.11 EGC33165.1 - 0.27 11.3 2.1 0.41 10.8 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Phg_2220_C PF09524.10 EGC33165.1 - 8.3 6.6 9.9 3.7 7.7 0.3 3.8 3 0 0 3 3 3 0 Conserved phage C-terminus (Phg_2220_C) Pro_isomerase PF00160.21 EGC33166.1 - 2e-50 171.2 0.1 3.2e-50 170.5 0.1 1.3 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_2 PF07719.17 EGC33166.1 - 5.9e-15 54.1 6.3 2.8e-05 23.9 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGC33166.1 - 8.5e-15 53.9 15.4 1.3e-08 34.3 0.7 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC33166.1 - 1.1e-07 32.2 10.2 6.7e-05 23.3 1.2 2.9 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGC33166.1 - 7.9e-07 29.3 0.2 0.0064 16.8 0.5 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC33166.1 - 1.2e-06 28.1 9.5 0.01 15.5 0.6 3.4 2 1 1 3 3 3 2 TPR repeat TPR_7 PF13176.6 EGC33166.1 - 6e-06 25.9 0.2 0.059 13.4 0.2 3.0 2 1 0 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC33166.1 - 9.2e-06 25.6 6.7 0.0046 17.0 1.3 3.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat DUF3808 PF10300.9 EGC33166.1 - 1.4e-05 24.0 1.9 2e-05 23.6 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_8 PF13181.6 EGC33166.1 - 5.9e-05 23.0 13.2 0.0012 18.9 0.3 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC33166.1 - 0.00014 22.0 6.6 0.15 12.5 0.3 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC33166.1 - 0.00017 21.4 0.9 0.012 15.5 0.1 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC33166.1 - 0.00027 21.5 0.0 0.39 11.7 0.0 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGC33166.1 - 0.00059 20.1 4.9 0.012 15.9 4.9 2.4 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC33166.1 - 0.00074 20.0 2.3 5.7 7.8 0.1 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC33166.1 - 0.0011 19.1 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC33166.1 - 0.0023 18.1 5.1 0.0025 18.0 2.1 2.2 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGC33166.1 - 0.0034 18.0 0.0 0.63 10.7 0.0 2.9 2 1 0 3 3 3 1 Tetratricopeptide repeat UxuA PF03786.13 EGC33166.1 - 0.029 13.2 0.1 0.041 12.7 0.1 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) TetR_C_19 PF17924.1 EGC33166.1 - 0.17 12.5 2.2 1.4 9.5 0.0 2.7 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain MIT PF04212.18 EGC33166.1 - 0.27 11.3 5.1 1.1 9.3 0.2 2.9 1 1 2 3 3 3 0 MIT (microtubule interacting and transport) domain PPR PF01535.20 EGC33166.1 - 0.45 10.9 4.2 6.5 7.2 0.1 3.5 4 0 0 4 4 3 0 PPR repeat Pkinase_Tyr PF07714.17 EGC33167.1 - 2e-66 224.0 0.0 2.6e-66 223.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC33167.1 - 1.1e-48 165.9 0.0 1.8e-48 165.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EGC33167.1 - 8.2e-07 28.3 7.1 0.00036 19.6 0.1 2.2 2 0 0 2 2 2 2 Haspin like kinase domain Kinase-like PF14531.6 EGC33167.1 - 1.4e-06 27.8 0.0 2.1e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGC33167.1 - 0.005 15.9 1.3 0.014 14.4 0.1 2.2 2 1 1 3 3 3 1 Seadornavirus VP7 Kdo PF06293.14 EGC33167.1 - 0.012 15.0 0.0 0.023 14.1 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC33167.1 - 0.14 12.1 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC33167.1 - 0.17 10.6 0.1 0.17 10.6 0.1 1.8 2 0 0 2 2 2 0 Fungal protein kinase FTA2 PF13095.6 EGC33167.1 - 0.64 9.6 3.1 14 5.2 0.1 2.8 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 RabGAP-TBC PF00566.18 EGC33168.1 - 9.5e-40 136.5 8.3 9.5e-40 136.5 8.3 4.7 4 2 0 4 4 4 1 Rab-GTPase-TBC domain MR_MLE_C PF13378.6 EGC33168.1 - 6.5e-13 48.8 0.0 1.4e-12 47.6 0.0 1.5 1 1 0 1 1 1 1 Enolase C-terminal domain-like EF-hand_6 PF13405.6 EGC33168.1 - 0.0002 21.0 10.1 0.0023 17.7 0.4 4.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.32 EGC33168.1 - 0.00048 19.5 3.7 0.00075 18.9 0.7 3.0 2 0 0 2 2 2 1 EF hand MR_MLE_N PF02746.16 EGC33168.1 - 0.00066 19.9 0.0 0.75 10.0 0.0 2.4 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain MAAL_C PF07476.11 EGC33168.1 - 0.0046 16.1 0.0 0.0099 15.1 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus EF-hand_7 PF13499.6 EGC33168.1 - 0.031 14.7 6.8 0.044 14.2 2.9 3.2 2 0 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 EGC33168.1 - 0.12 11.9 1.2 0.58 9.8 0.5 2.5 2 0 0 2 2 2 0 EF hand KAsynt_C_assoc PF16197.5 EGC33168.1 - 0.21 12.0 2.4 0.83 10.1 2.4 2.0 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Met_synt_B12 PF02965.17 EGC33169.1 - 2.1e-119 398.0 0.1 3.5e-119 397.3 0.1 1.4 1 0 0 1 1 1 1 Vitamin B12 dependent methionine synthase, activation domain S-methyl_trans PF02574.16 EGC33169.1 - 1.9e-76 257.4 0.0 4.7e-76 256.1 0.0 1.7 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Pterin_bind PF00809.22 EGC33169.1 - 2.8e-57 194.2 0.1 7.2e-57 192.9 0.1 1.8 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.17 EGC33169.1 - 5e-23 81.3 0.5 2.7e-22 79.0 0.0 2.6 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.19 EGC33169.1 - 1.4e-17 63.8 0.6 4.8e-17 62.1 0.3 2.1 2 0 0 2 2 2 1 B12 binding domain Methyltransf_12 PF08242.12 EGC33171.1 - 5.1e-16 59.2 1.0 1.9e-15 57.4 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC33171.1 - 2.1e-07 30.8 0.4 1.2e-06 28.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC33171.1 - 2.4e-06 27.5 0.0 6.3e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC33171.1 - 9e-06 26.3 0.0 2.9e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC33171.1 - 0.00067 20.3 0.1 0.0049 17.5 0.0 2.5 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_28 PF02636.17 EGC33171.1 - 0.047 13.3 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase DUF4403 PF14356.6 EGC33171.1 - 0.05 12.3 0.0 0.085 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4403) DUF5383 PF17355.2 EGC33172.1 - 4.2 7.8 8.2 0.25 11.7 0.8 2.6 2 1 1 3 3 3 0 Family of unknown function (DUF5383) Peptidase_C50 PF03568.17 EGC33173.1 - 5.5e-67 226.6 0.0 5.5e-67 226.6 0.0 4.6 4 1 0 4 4 4 2 Peptidase family C50 CHAT PF12770.7 EGC33173.1 - 6.8e-06 25.7 0.0 0.00051 19.5 0.0 3.1 2 1 0 2 2 2 1 CHAT domain TPR_2 PF07719.17 EGC33173.1 - 1.6e-05 24.6 0.8 66 4.0 0.0 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC33173.1 - 0.0023 18.2 0.2 7.8 6.9 0.0 5.2 5 1 1 6 6 6 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC33173.1 - 0.094 13.0 7.4 13 6.3 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat SUIM_assoc PF16619.5 EGC33173.1 - 4 7.6 19.0 0.68 10.0 0.2 4.1 4 0 0 4 4 4 0 Unstructured region C-term to UIM in Ataxin3 PA14 PF07691.12 EGC33174.1 - 1.6e-11 44.2 0.2 2.6e-11 43.5 0.2 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33174.1 - 2.3e-10 40.1 59.2 2.9e-06 27.1 5.7 12.6 13 0 0 13 13 13 6 Dictyostelium (slime mold) repeat Integrin_b_cyt PF08725.11 EGC33174.1 - 0.14 11.8 0.2 0.43 10.3 0.2 1.8 1 1 0 1 1 1 0 Integrin beta cytoplasmic domain DUF179 PF02622.15 EGC33175.1 - 4.8e-31 107.9 0.0 7.2e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 CBM49 PF09478.10 EGC33176.1 - 8.9e-05 22.7 1.4 9.3e-05 22.7 0.2 1.7 2 1 0 2 2 2 1 Carbohydrate binding domain CBM49 Ras PF00071.22 EGC33177.1 - 3.3e-31 108.1 5.3 6.2e-31 107.2 5.3 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC33177.1 - 8.3e-14 51.8 0.1 2.6e-13 50.2 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC33177.1 - 4.2e-09 36.1 0.2 6.1e-09 35.6 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC33177.1 - 0.0064 16.0 3.3 0.01 15.4 3.3 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Connexin PF00029.19 EGC33177.1 - 0.026 14.3 0.1 0.037 13.8 0.1 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC33177.1 - 1.9 7.1 3.5 2.5 6.8 3.5 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGC33177.1 - 3.4 8.7 8.2 0.39 11.7 1.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Conotoxin PF02950.17 EGC33178.1 - 3.3 8.8 0.0 3.3 8.8 0.0 7.1 2 1 1 3 3 3 0 Conotoxin Porphobil_deam PF01379.20 EGC33179.1 - 4.9e-78 261.3 0.0 6.1e-78 261.0 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.15 EGC33179.1 - 6e-22 77.8 0.1 1.2e-21 76.8 0.1 1.6 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Pkinase PF00069.25 EGC33180.1 - 3.5e-34 118.4 0.3 3.5e-34 118.4 0.3 2.7 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33180.1 - 6.4e-14 51.9 0.0 1.8e-13 50.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase zf-C3HC4 PF00097.25 EGC33180.1 - 3.2e-07 30.1 7.4 7e-07 29.0 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC33180.1 - 3.4e-07 30.5 5.7 6.7e-07 29.5 5.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC33180.1 - 3.7e-06 26.9 4.6 8.9e-06 25.6 1.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC33180.1 - 7.9e-06 25.7 7.1 1.6e-05 24.8 7.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC33180.1 - 0.0002 21.1 7.4 0.00074 19.3 7.4 1.9 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC33180.1 - 0.00046 20.3 4.0 0.0014 18.8 4.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.6 EGC33180.1 - 0.0023 17.7 9.0 0.01 15.7 9.1 2.1 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.6 EGC33180.1 - 0.0037 16.6 0.0 0.0037 16.6 0.0 2.1 2 0 0 2 2 1 1 Kinase-like Prok-RING_4 PF14447.6 EGC33180.1 - 0.0049 16.7 6.3 0.022 14.6 6.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 Rootletin PF15035.6 EGC33180.1 - 0.0076 16.3 37.2 0.082 12.9 21.3 3.0 1 1 2 3 3 3 2 Ciliary rootlet component, centrosome cohesion zf-ANAPC11 PF12861.7 EGC33180.1 - 0.013 15.6 0.4 0.027 14.5 0.4 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGC33180.1 - 0.014 15.7 4.0 0.039 14.2 4.0 1.9 1 0 0 1 1 1 0 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGC33180.1 - 0.17 11.7 10.1 0.022 14.5 5.7 1.9 2 1 0 2 2 1 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.12 EGC33180.1 - 0.21 11.6 7.7 0.51 10.3 6.5 2.1 2 0 0 2 2 2 0 zinc-ribbons DUF3584 PF12128.8 EGC33180.1 - 0.34 8.4 36.2 1.2 6.5 5.9 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF1664 PF07889.12 EGC33180.1 - 2.7 8.0 17.5 4 7.5 5.5 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Pox_A_type_inc PF04508.12 EGC33180.1 - 4.4 7.3 15.9 1.8 8.6 1.6 4.0 2 1 1 3 3 3 0 Viral A-type inclusion protein repeat PHD PF00628.29 EGC33180.1 - 7.8 6.5 6.6 27 4.7 6.7 2.0 1 1 0 1 1 1 0 PHD-finger zf-RING_10 PF16685.5 EGC33180.1 - 9 6.5 7.5 6.1 7.1 3.9 2.5 2 0 0 2 2 2 0 zinc RING finger of MSL2 TK PF00265.18 EGC33181.1 - 1.9e-64 216.8 1.1 2.8e-64 216.2 1.1 1.2 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.6 EGC33181.1 - 9.1e-05 22.5 0.2 0.00017 21.7 0.2 1.4 1 0 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGC33181.1 - 0.0056 16.6 0.2 0.0078 16.1 0.2 1.2 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea Flag1_repress PF03614.13 EGC33181.1 - 0.057 13.2 0.1 0.084 12.7 0.1 1.2 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Pro-kuma_activ PF09286.11 EGC33182.1 - 7.5e-34 117.1 0.4 1.3e-33 116.3 0.4 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC33182.1 - 3.1e-06 26.7 4.1 5.6e-06 25.8 4.1 1.3 1 0 0 1 1 1 1 Subtilase family TFIIA PF03153.13 EGC33183.1 - 2.3e-43 149.8 27.4 2.7e-28 100.1 17.7 2.1 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit RXLR PF16810.5 EGC33183.1 - 0.085 13.3 0.2 0.19 12.2 0.2 1.5 1 0 0 1 1 1 0 RXLR phytopathogen effector protein, Avirulence activity FSA_C PF10479.9 EGC33183.1 - 4.7 5.2 7.6 5.6 5.0 7.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus YppG PF14179.6 EGC33183.1 - 5.8 7.7 11.3 0.3 11.8 3.7 2.1 1 1 1 2 2 2 0 YppG-like protein adh_short PF00106.25 EGC33184.1 - 1.8e-35 122.2 0.0 2.5e-35 121.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33184.1 - 2.4e-23 82.9 0.0 2.9e-23 82.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33184.1 - 9.3e-06 25.7 0.0 1.8e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC33184.1 - 0.00012 21.6 0.1 0.00022 20.7 0.1 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) GDP_Man_Dehyd PF16363.5 EGC33184.1 - 0.032 13.6 0.3 0.1 12.0 0.0 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Rtt106 PF08512.12 EGC33185.1 - 4e-30 104.1 0.0 1.1e-25 89.8 0.0 2.8 2 0 0 2 2 2 2 Histone chaperone Rttp106-like POB3_N PF17292.2 EGC33185.1 - 2.8e-24 85.4 0.3 2.7e-21 75.8 0.1 3.5 3 1 0 3 3 3 1 POB3-like N-terminal PH domain SSrecog PF03531.14 EGC33185.1 - 2.2e-18 65.9 0.6 2.2e-18 65.9 0.6 2.2 2 0 0 2 2 2 1 Structure-specific recognition protein (SSRP1) BUD22 PF09073.10 EGC33185.1 - 0.077 12.3 30.9 0.48 9.7 13.1 2.1 2 0 0 2 2 2 0 BUD22 PPP4R2 PF09184.11 EGC33185.1 - 0.53 9.8 25.5 0.97 9.0 5.8 2.2 2 0 0 2 2 2 0 PPP4R2 Pox_Ag35 PF03286.14 EGC33185.1 - 2.9 7.6 24.5 0.017 14.9 7.4 2.3 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SDA1 PF05285.12 EGC33185.1 - 3.1 7.2 34.8 0.17 11.2 8.9 2.2 2 0 0 2 2 2 0 SDA1 RNA_pol_Rpc4 PF05132.14 EGC33185.1 - 3.4 8.1 14.4 3.9 7.9 3.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 FAM176 PF14851.6 EGC33185.1 - 6.2 6.5 22.1 0.022 14.4 3.9 2.5 2 0 0 2 2 2 0 FAM176 family SURF2 PF05477.11 EGC33185.1 - 6.6 6.4 20.0 1.6 8.3 5.4 2.3 2 0 0 2 2 2 0 Surfeit locus protein 2 (SURF2) RXT2_N PF08595.11 EGC33185.1 - 7 6.7 20.0 1.1 9.3 7.3 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Sigma70_ner PF04546.13 EGC33185.1 - 8 6.3 27.9 7 6.5 9.5 2.5 2 0 0 2 2 2 0 Sigma-70, non-essential region Ribonucleas_3_3 PF14622.6 EGC33186.1 - 0.00011 22.4 0.0 0.00023 21.3 0.0 1.5 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGC33186.1 - 0.0015 19.1 0.1 0.0015 19.1 0.1 3.2 2 2 0 2 2 2 1 Ribonuclease III domain DUF4337 PF14235.6 EGC33186.1 - 0.019 15.1 1.1 0.041 14.0 1.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Zip PF02535.22 EGC33186.1 - 0.33 10.1 0.6 0.46 9.7 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC33186.1 - 1.7 7.3 5.1 3.2 6.4 5.1 1.4 1 0 0 1 1 1 0 Presenilin Connexin PF00029.19 EGC33186.1 - 1.8 8.3 4.0 3.9 7.2 4.0 1.5 1 0 0 1 1 1 0 Connexin Gti1_Pac2 PF09729.9 EGC33186.1 - 2.8 8.0 18.3 1.1 9.3 5.3 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family DASH_Spc19 PF08287.11 EGC33186.1 - 4 7.3 15.1 0.36 10.7 9.9 1.9 2 0 0 2 2 2 0 Spc19 RINGv PF12906.7 EGC33187.1 - 7.2e-07 29.2 9.7 7.2e-07 29.2 9.7 2.6 2 0 0 2 2 2 1 RING-variant domain Erf4 PF10256.9 EGC33188.1 - 7.2e-09 35.8 0.2 1.2e-08 35.0 0.2 1.3 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Peptidase_M15_2 PF05951.13 EGC33188.1 - 0.14 11.8 0.1 0.24 11.0 0.0 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Tom22 PF04281.13 EGC33188.1 - 0.23 11.3 0.0 0.25 11.2 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RNA_pol_Rbc25 PF08292.12 EGC33189.1 - 7.8e-35 119.9 0.5 1.2e-34 119.3 0.5 1.3 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.17 EGC33189.1 - 1.2e-12 48.0 0.1 2.7e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 CAP PF00188.26 EGC33190.1 - 1.7e-09 38.5 7.0 1.7e-09 38.5 7.0 1.9 2 0 0 2 2 2 1 Cysteine-rich secretory protein family CAP PF00188.26 EGC33191.1 - 6.7e-15 56.0 0.9 1.2e-14 55.2 0.9 1.4 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.26 EGC33192.1 - 8e-14 52.6 0.9 2.1e-13 51.2 0.9 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Transglut_core PF01841.19 EGC33193.1 - 4.9e-14 52.7 0.0 9.6e-14 51.8 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ribonuc_red_sm PF00268.21 EGC33194.1 - 2.9e-122 407.5 0.7 3.6e-122 407.2 0.7 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain DUF4744 PF15918.5 EGC33194.1 - 0.11 13.4 0.0 0.27 12.1 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4744) Transketolase_N PF00456.21 EGC33195.1 - 2.1e-112 375.4 0.1 3e-112 374.9 0.1 1.2 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.24 EGC33195.1 - 1e-41 142.6 0.0 2e-41 141.6 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.6 EGC33195.1 - 2.6e-10 40.0 0.1 3e-08 33.2 0.0 2.5 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.20 EGC33195.1 - 4.8e-10 39.4 0.0 7.9e-09 35.5 0.0 2.7 3 0 0 3 3 3 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.21 EGC33195.1 - 1.7e-05 24.6 0.0 0.00035 20.4 0.1 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.20 EGC33195.1 - 0.038 13.0 0.1 0.063 12.2 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component PHP PF02811.19 EGC33195.1 - 0.11 12.8 0.1 0.48 10.7 0.1 1.9 1 1 0 1 1 1 0 PHP domain Sybindin PF04099.12 EGC33196.1 - 6.4e-36 123.4 1.6 7e-36 123.3 1.6 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGC33196.1 - 0.00047 20.3 0.7 0.00081 19.5 0.7 1.4 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region AAA_7 PF12775.7 EGC33197.1 - 1.5e-08 34.4 1.2 0.32 10.5 0.0 5.3 4 1 0 4 4 4 3 P-loop containing dynein motor region AAA PF00004.29 EGC33197.1 - 5.7e-07 30.0 0.6 0.00011 22.6 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC33197.1 - 2.3e-06 27.9 0.0 1 9.6 0.0 5.1 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGC33197.1 - 4.4e-06 27.2 0.0 0.13 12.6 0.0 3.9 3 0 0 3 3 3 2 AAA ATPase domain AAA_5 PF07728.14 EGC33197.1 - 0.00036 20.6 0.0 3.2 7.8 0.0 5.1 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGC33197.1 - 0.034 14.7 0.3 32 5.1 0.0 5.2 3 0 0 3 3 3 0 AAA domain HTH_57 PF18679.1 EGC33197.1 - 0.054 13.8 2.1 0.23 11.8 2.1 2.2 1 0 0 1 1 1 0 ThcOx helix turn helix domain Mating_N PF12731.7 EGC33197.1 - 0.15 12.2 1.2 1.9 8.6 0.0 3.5 2 0 0 2 2 2 0 Mating-type protein beta 1 DASH_Dam1 PF08653.10 EGC33197.1 - 0.57 10.0 7.5 9.3 6.1 0.0 5.7 5 0 0 5 5 5 0 DASH complex subunit Dam1 Adaptin_N PF01602.20 EGC33198.1 - 5.2e-115 385.0 5.7 6.3e-115 384.7 5.7 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.16 EGC33198.1 - 6.4e-36 123.0 0.1 5.3e-35 120.0 0.0 2.6 3 0 0 3 3 3 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.20 EGC33198.1 - 1.3e-18 67.3 0.9 1.3e-18 67.3 0.9 3.3 4 0 0 4 4 4 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGC33198.1 - 2.6e-07 30.8 2.5 0.0012 18.9 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGC33198.1 - 0.059 13.8 0.3 0.87 10.0 0.0 2.8 3 1 1 4 4 4 0 HEAT repeats RasGEF_N_2 PF14663.6 EGC33198.1 - 0.17 12.3 1.9 0.28 11.6 0.1 2.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain BLOC1_2 PF10046.9 EGC33198.1 - 0.34 11.3 2.2 0.97 9.8 2.2 1.8 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 TFIIA PF03153.13 EGC33198.1 - 5.6 6.9 16.6 10 6.0 16.6 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit CDC4_D PF16856.5 EGC33199.1 - 0.19 11.6 3.0 2.7 7.9 1.1 2.8 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain Chordopox_G3 PF06129.12 EGC33199.1 - 3.1 8.5 9.6 6.2 7.6 3.4 2.3 2 0 0 2 2 2 0 Chordopoxvirus G3 protein SHOCT PF09851.9 EGC33200.1 - 0.0015 18.2 1.9 0.0025 17.5 1.9 1.3 1 0 0 1 1 1 1 Short C-terminal domain DUF829 PF05705.14 EGC33202.1 - 2.3e-48 165.2 0.3 3.3e-48 164.7 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4652 PF15525.6 EGC33202.1 - 0.86 9.4 14.1 1.8 8.3 14.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) TFIIE_alpha PF02002.17 EGC33203.1 - 5e-15 55.2 6.4 1.5e-14 53.7 6.4 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.20 EGC33203.1 - 0.0098 16.2 0.5 0.026 14.9 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.15 EGC33203.1 - 0.048 13.3 0.3 0.17 11.6 0.3 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding TF_Zn_Ribbon PF08271.12 EGC33203.1 - 0.082 12.4 0.6 0.19 11.2 0.6 1.6 1 0 0 1 1 1 0 TFIIB zinc-binding TFIIE-A_C PF11521.8 EGC33203.1 - 1.8 8.9 7.0 2.9 8.2 5.5 2.2 1 1 1 2 2 2 0 C-terminal general transcription factor TFIIE alpha GrpB PF04229.14 EGC33204.1 - 1.5e-42 145.5 0.0 1.7e-42 145.3 0.0 1.0 1 0 0 1 1 1 1 GrpB protein DUF1794 PF08768.11 EGC33205.1 - 1.1e-38 132.6 0.0 1.2e-38 132.4 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Cofilin_ADF PF00241.20 EGC33206.1 - 6.8e-26 90.4 0.7 7.8e-26 90.3 0.7 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XAP5 PF04921.14 EGC33207.1 - 1.1e-83 280.9 15.3 1.4e-83 280.6 15.3 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator SMN PF06003.12 EGC33207.1 - 0.0075 15.6 5.8 0.014 14.6 5.8 1.4 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Presenilin PF01080.17 EGC33207.1 - 0.83 8.3 3.1 0.97 8.1 3.1 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC33207.1 - 3.1 6.0 15.1 4 5.6 15.1 1.1 1 0 0 1 1 1 0 CDC45-like protein CBM49 PF09478.10 EGC33208.1 - 2e-12 47.2 4.0 3e-12 46.7 4.0 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 HcyBio PF01837.16 EGC33208.1 - 0.026 13.4 0.2 0.032 13.1 0.2 1.1 1 0 0 1 1 1 0 Homocysteine biosynthesis enzyme, sulfur-incorporation DUF973 PF06157.11 EGC33209.1 - 0.18 10.8 2.6 0.22 10.5 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF973) RDD PF06271.12 EGC33209.1 - 5.3 7.2 10.0 1.4 9.1 1.7 2.4 1 1 1 2 2 2 0 RDD family Kinesin PF00225.23 EGC33210.1 - 1.4e-90 303.6 1.2 1.6e-90 303.4 1.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGC33210.1 - 1.9e-19 70.1 0.1 3.1e-19 69.4 0.1 1.4 1 0 0 1 1 1 1 Microtubule binding SPX PF03105.19 EGC33211.1 - 0.077 12.9 6.0 3 7.7 0.1 2.0 2 0 0 2 2 2 0 SPX domain ALG3 PF05208.13 EGC33212.1 - 9.7e-132 439.7 41.9 5.6e-95 318.8 28.6 2.0 2 0 0 2 2 2 2 ALG3 protein Seryl_tRNA_N PF02403.22 EGC33213.1 - 0.0057 16.9 12.7 0.0057 16.9 12.7 6.6 3 1 2 6 6 6 2 Seryl-tRNA synthetase N-terminal domain HalX PF08663.10 EGC33213.1 - 0.031 14.6 8.6 0.047 14.0 0.7 3.8 3 0 0 3 3 3 0 HalX domain DUF2730 PF10805.8 EGC33213.1 - 3 8.0 14.9 4.4 7.4 3.2 3.9 2 1 2 4 4 4 0 Protein of unknown function (DUF2730) DUF948 PF06103.11 EGC33213.1 - 5.4 7.4 19.3 0.092 13.0 1.6 4.3 3 2 1 4 4 4 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGC33213.1 - 5.6 7.5 19.0 11 6.5 0.3 4.6 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein zf-RING_2 PF13639.6 EGC33215.1 - 1.2e-10 41.6 12.8 2e-10 40.8 12.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33215.1 - 5.1e-07 29.4 12.4 9.1e-07 28.6 12.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC33215.1 - 6.9e-07 29.0 9.1 1.1e-06 28.3 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33215.1 - 1.3e-06 28.6 8.2 3.6e-06 27.2 8.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC33215.1 - 2.3e-06 27.4 14.4 4.6e-06 26.4 14.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC33215.1 - 3.1e-05 24.2 41.0 4.4e-05 23.7 41.0 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC33215.1 - 0.00023 21.0 13.2 0.00045 20.1 13.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC33215.1 - 0.0028 17.7 3.8 0.0062 16.6 3.8 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.6 EGC33215.1 - 0.0034 17.2 8.3 0.0094 15.8 8.5 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC33215.1 - 0.0047 17.0 5.4 0.01 16.0 5.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EGC33215.1 - 0.018 15.1 8.4 0.018 15.1 6.6 2.0 1 1 1 2 2 2 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC33215.1 - 0.066 13.4 13.6 0.19 11.9 13.6 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC33215.1 - 0.37 10.6 9.0 0.75 9.6 9.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger MCD PF05292.11 EGC33215.1 - 0.61 9.6 4.8 0.11 12.1 0.6 1.8 2 0 0 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain Zn_ribbon_17 PF17120.5 EGC33215.1 - 0.7 9.6 9.5 1.2 8.8 9.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 EGC33215.1 - 3.5 7.8 8.9 6.9 6.8 8.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF1771 PF08590.10 EGC33217.1 - 3.5e-18 65.7 11.5 5.2e-18 65.2 11.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGC33217.1 - 1.9e-08 34.5 0.1 4.5e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Smr domain TIG PF01833.24 EGC33218.1 - 8.1e-09 35.4 32.3 8.2e-06 25.8 0.7 6.2 6 1 1 7 7 7 4 IPT/TIG domain CBM_6 PF03422.15 EGC33218.1 - 0.079 13.3 0.2 35 4.7 0.0 3.8 3 0 0 3 3 3 0 Carbohydrate binding module (family 6) AMPK1_CBM PF16561.5 EGC33218.1 - 0.081 13.1 0.1 1.3 9.3 0.0 3.0 3 0 0 3 3 3 0 Glycogen recognition site of AMP-activated protein kinase CARDB PF07705.11 EGC33218.1 - 0.75 10.1 9.3 0.049 13.9 1.1 3.3 4 0 0 4 4 4 0 CARDB SRP-alpha_N PF04086.13 EGC33219.1 - 4.1 7.2 9.6 4.4 7.1 9.6 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal OTU PF02338.19 EGC33220.1 - 1.9e-09 38.1 0.1 2.5e-09 37.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease FNIP PF05725.12 EGC33221.1 - 1.2e-08 35.0 12.1 6.1e-05 23.1 0.4 8.4 8 1 1 9 9 9 5 FNIP Repeat DUF2207 PF09972.9 EGC33222.1 - 0.5 9.1 4.7 0.54 9.0 4.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DHHC PF01529.20 EGC33222.1 - 0.82 9.8 8.6 1.1 9.4 8.6 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ferlin_C PF16165.5 EGC33222.1 - 1.4 8.8 12.0 0.092 12.7 6.3 1.8 2 0 0 2 2 2 0 Ferlin C-terminus Guanylate_cyc PF00211.20 EGC33223.1 - 2e-27 96.0 1.1 7.4e-27 94.1 1.1 1.9 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HATPase_c PF02518.26 EGC33223.1 - 1.7e-17 64.0 0.2 7.3e-16 58.7 0.0 3.2 2 1 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC33223.1 - 2e-17 63.4 0.1 9.4e-10 38.7 0.1 2.9 2 0 0 2 2 2 2 Response regulator receiver domain DUF2207 PF09972.9 EGC33223.1 - 0.00028 19.8 0.0 0.00028 19.8 0.0 3.1 2 1 0 3 3 3 2 Predicted membrane protein (DUF2207) TPR_2 PF07719.17 EGC33223.1 - 0.017 15.2 0.2 0.04 14.0 0.2 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1634 PF07843.11 EGC33223.1 - 0.083 13.0 0.1 25 5.0 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1634) SR-25 PF10500.9 EGC33223.1 - 0.58 9.7 0.0 0.58 9.7 0.0 7.4 6 1 2 8 8 8 0 Nuclear RNA-splicing-associated protein PTS_EIIB PF00367.20 EGC33224.1 - 0.13 11.8 0.6 0.8 9.3 0.0 2.0 2 0 0 2 2 2 0 phosphotransferase system, EIIB MMR_HSR1 PF01926.23 EGC33225.1 - 3.3e-05 24.0 0.0 3.3e-05 23.9 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGC33225.1 - 5.2e-05 22.7 0.0 5.8e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 AIG1 family Dynamin_N PF00350.23 EGC33225.1 - 0.047 13.7 0.0 0.047 13.7 0.0 1.1 1 0 0 1 1 1 0 Dynamin family AIG1 PF04548.16 EGC33226.1 - 4.5e-10 39.2 1.9 1.3e-09 37.7 1.9 1.8 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGC33226.1 - 1.3e-08 34.9 1.6 1.3e-08 34.9 1.6 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase zinc_ribbon_4 PF13717.6 EGC33226.1 - 0.00019 21.3 38.5 0.022 14.6 1.4 6.3 6 0 0 6 6 6 4 zinc-ribbon domain GTP_EFTU PF00009.27 EGC33226.1 - 0.00022 20.8 0.3 0.00022 20.8 0.3 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.6 EGC33226.1 - 0.0006 19.5 0.2 0.0014 18.3 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC33226.1 - 0.00065 19.6 1.3 0.0017 18.2 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_22 PF13401.6 EGC33226.1 - 0.0019 18.5 0.2 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain Dynamin_N PF00350.23 EGC33226.1 - 0.0043 17.1 18.5 0.21 11.6 0.1 4.6 4 2 0 4 4 4 2 Dynamin family ABC_tran PF00005.27 EGC33226.1 - 0.005 17.4 4.8 0.0077 16.7 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_16 PF13191.6 EGC33226.1 - 0.0071 16.7 0.0 0.014 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain T2SSE PF00437.20 EGC33226.1 - 0.012 14.7 0.5 0.03 13.4 0.5 1.7 1 0 0 1 1 1 0 Type II/IV secretion system protein PRK PF00485.18 EGC33226.1 - 0.026 14.3 0.1 0.069 12.9 0.1 1.8 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family FtsK_SpoIIIE PF01580.18 EGC33226.1 - 0.061 12.7 0.1 0.14 11.5 0.1 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family V-SNARE PF05008.15 EGC33226.1 - 0.072 13.5 0.4 0.072 13.5 0.4 3.8 2 1 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF87 PF01935.17 EGC33226.1 - 0.11 12.6 0.0 0.11 12.6 0.0 3.6 3 1 1 4 4 4 0 Helicase HerA, central domain Ploopntkinase3 PF18751.1 EGC33226.1 - 0.13 12.2 0.0 0.26 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 RNA_helicase PF00910.22 EGC33226.1 - 0.21 12.0 0.0 0.21 12.0 0.0 4.6 5 1 1 6 6 6 0 RNA helicase AAA_21 PF13304.6 EGC33226.1 - 2.2 8.0 6.8 1.3 8.8 0.2 2.8 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system DUF4200 PF13863.6 EGC33226.1 - 6.2 7.3 18.2 2.4 8.6 1.0 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4200) AIG1 PF04548.16 EGC33227.1 - 1e-10 41.3 2.7 4.5e-10 39.2 2.7 2.1 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGC33227.1 - 8.4e-09 35.5 1.3 8.4e-09 35.5 1.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGC33227.1 - 0.00014 22.1 0.1 0.016 15.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGC33227.1 - 0.00018 21.5 1.4 0.00042 20.2 0.1 2.3 2 0 0 2 2 2 1 RsgA GTPase GTP_EFTU PF00009.27 EGC33227.1 - 0.0011 18.6 0.1 0.0011 18.6 0.1 2.9 3 1 0 3 3 2 1 Elongation factor Tu GTP binding domain ABC_tran PF00005.27 EGC33227.1 - 0.0029 18.1 0.0 0.0029 18.1 0.0 2.9 2 1 0 2 2 1 1 ABC transporter RNA_helicase PF00910.22 EGC33227.1 - 0.0036 17.7 0.0 0.038 14.4 0.0 2.9 1 0 0 1 1 1 1 RNA helicase AAA_16 PF13191.6 EGC33227.1 - 0.0042 17.5 0.0 0.0086 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGC33227.1 - 0.0053 16.5 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.18 EGC33227.1 - 0.013 15.3 0.2 0.057 13.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.23 EGC33227.1 - 0.017 15.2 0.6 0.16 12.1 0.1 5.9 5 2 1 6 6 4 0 Dynamin family ssDNA_DBD PF18333.1 EGC33227.1 - 0.025 14.7 0.4 0.025 14.7 0.4 2.2 2 0 0 2 2 2 0 Non-canonical single-stranded DNA-binding domain AAA_7 PF12775.7 EGC33227.1 - 0.034 13.7 0.1 0.069 12.7 0.1 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region T2SSE PF00437.20 EGC33227.1 - 0.087 11.9 0.3 0.2 10.7 0.3 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein NACHT PF05729.12 EGC33227.1 - 0.11 12.4 0.0 0.38 10.6 0.0 1.9 2 0 0 2 2 2 0 NACHT domain Cytochrom_B562 PF07361.11 EGC33227.1 - 0.16 12.6 9.9 1.1 9.9 0.9 2.8 2 0 0 2 2 2 0 Cytochrome b562 FeoB_N PF02421.18 EGC33227.1 - 0.19 11.2 1.8 0.63 9.6 0.1 2.6 3 0 0 3 3 3 0 Ferrous iron transport protein B DUF87 PF01935.17 EGC33227.1 - 0.65 10.1 0.0 0.65 10.1 0.0 3.8 3 1 1 4 4 3 0 Helicase HerA, central domain AAA_21 PF13304.6 EGC33227.1 - 1.4 8.6 10.1 3.3 7.4 0.6 3.4 3 0 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system LRR_8 PF13855.6 EGC33230.1 - 0.00036 20.2 13.4 7.1 6.5 0.3 7.9 9 0 0 9 9 9 4 Leucine rich repeat PHF12_MRG_bd PF16737.5 EGC33230.1 - 0.15 11.8 0.6 29 4.5 0.1 2.9 2 0 0 2 2 2 0 PHD finger protein 12 MRG binding domain DDE_Tnp_1_7 PF13843.6 EGC33232.1 - 1.2e-14 54.4 1.4 1.5e-14 54.1 1.4 1.1 1 0 0 1 1 1 1 Transposase IS4 DUF505 PF04458.12 EGC33232.1 - 0.091 11.1 0.4 0.69 8.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF505) DUF1363 PF07101.11 EGC33232.1 - 0.99 9.7 4.8 5.4 7.3 0.2 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1363) Flagellar_rod PF05149.12 EGC33233.1 - 0.074 12.5 0.5 0.87 9.0 0.0 2.0 1 1 1 2 2 2 0 Paraflagellar rod protein Aminotran_1_2 PF00155.21 EGC33234.1 - 5.4e-24 85.0 0.0 6.5e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_3 PF00202.21 EGC33234.1 - 0.026 13.2 0.0 0.056 12.1 0.0 1.5 1 1 0 1 1 1 0 Aminotransferase class-III Uso1_p115_C PF04871.13 EGC33237.1 - 0.28 11.6 2.3 0.39 11.1 2.3 1.2 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Hamartin PF04388.12 EGC33237.1 - 0.34 9.5 12.7 0.4 9.3 12.7 1.0 1 0 0 1 1 1 0 Hamartin protein WD40 PF00400.32 EGC33238.1 - 1.3e-08 35.3 8.5 0.00026 21.7 0.3 5.9 6 1 1 7 7 7 2 WD domain, G-beta repeat Dfp1_Him1_M PF08630.10 EGC33238.1 - 0.79 9.9 7.1 8.8 6.6 0.8 3.0 4 0 0 4 4 4 0 Dfp1/Him1, central region DUF5611 PF18446.1 EGC33238.1 - 1.2 10.1 4.4 1.5 9.7 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5611) Ribosomal_L11_N PF03946.14 EGC33240.1 - 1.1e-21 76.4 0.3 2.4e-21 75.3 0.3 1.6 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.19 EGC33240.1 - 4.6e-15 55.9 0.2 1.8e-14 54.0 0.1 1.9 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain SOR_SNZ PF01680.17 EGC33241.1 - 8.5e-113 375.2 7.0 1.4e-112 374.5 7.0 1.3 1 0 0 1 1 1 1 SOR/SNZ family ThiG PF05690.14 EGC33241.1 - 5.4e-08 32.4 8.6 2.4e-07 30.3 0.3 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.17 EGC33241.1 - 3.2e-05 23.2 0.4 0.012 14.8 0.1 2.5 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.21 EGC33241.1 - 0.00019 20.7 0.1 0.081 12.1 0.0 2.5 2 1 0 2 2 2 2 Indole-3-glycerol phosphate synthase NanE PF04131.14 EGC33241.1 - 0.00048 19.4 1.5 0.022 13.9 0.0 3.1 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase TetR_C_27 PF17935.1 EGC33241.1 - 0.00092 19.2 0.0 0.0026 17.8 0.0 1.8 1 0 0 1 1 1 1 Tetracyclin repressor-like, C-terminal domain His_biosynth PF00977.21 EGC33241.1 - 0.0014 18.1 0.9 0.13 11.7 0.0 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein FMN_dh PF01070.18 EGC33241.1 - 0.013 14.6 0.2 0.07 12.1 0.0 2.1 2 0 0 2 2 2 0 FMN-dependent dehydrogenase Fapy_DNA_glyco PF01149.24 EGC33241.1 - 0.029 15.0 0.0 0.14 12.8 0.0 2.1 2 0 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase N-terminal domain OMPdecase PF00215.24 EGC33241.1 - 0.053 13.1 0.3 1.4 8.5 0.0 2.3 1 1 1 2 2 2 0 Orotidine 5'-phosphate decarboxylase / HUMPS family Peptidase_C69 PF03577.15 EGC33241.1 - 0.071 12.0 0.2 0.11 11.5 0.2 1.1 1 0 0 1 1 1 0 Peptidase family C69 NMO PF03060.15 EGC33241.1 - 0.08 12.3 3.5 0.098 12.0 0.1 2.2 2 0 0 2 2 2 0 Nitronate monooxygenase SLBP_RNA_bind PF15247.6 EGC33242.1 - 1.2e-29 102.2 3.2 1.2e-29 102.2 3.2 2.2 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain MORN PF02493.20 EGC33243.1 - 6.8e-08 32.0 26.4 0.047 13.6 1.6 5.9 6 0 0 6 6 6 5 MORN repeat SET PF00856.28 EGC33243.1 - 0.0018 18.7 3.2 0.0084 16.5 0.1 2.7 2 2 0 2 2 2 1 SET domain Pkinase_Tyr PF07714.17 EGC33244.1 - 7.6e-53 179.4 0.0 1.3e-52 178.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC33244.1 - 3.1e-45 154.6 0.0 6e-45 153.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain COR PF16095.5 EGC33244.1 - 3.1e-41 141.4 0.1 5.9e-41 140.4 0.1 1.5 1 0 0 1 1 1 1 C-terminal of Roc, COR, domain Roc PF08477.13 EGC33244.1 - 4.9e-25 88.1 0.5 3.1e-24 85.5 0.1 2.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC33244.1 - 8.3e-14 51.5 2.2 6.7e-13 48.5 0.2 2.4 2 0 0 2 2 2 1 Ras family Arf PF00025.21 EGC33244.1 - 4.9e-08 32.6 0.1 1.1e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_8 PF13855.6 EGC33244.1 - 2.2e-06 27.3 6.9 2.2e-06 27.3 2.1 3.0 2 1 1 3 3 2 2 Leucine rich repeat LRR_4 PF12799.7 EGC33244.1 - 0.0002 21.7 7.4 0.00037 20.8 1.6 3.2 1 1 1 2 2 2 2 Leucine Rich repeats (2 copies) Gtr1_RagA PF04670.12 EGC33244.1 - 0.00068 19.1 2.0 0.0058 16.0 0.0 2.7 2 0 0 2 2 2 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGC33244.1 - 0.0012 18.7 0.3 0.0029 17.3 0.3 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.23 EGC33244.1 - 0.0033 17.5 0.0 0.011 15.8 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC33244.1 - 0.018 15.0 3.3 0.042 13.8 0.2 2.9 3 0 0 3 3 3 0 RsgA GTPase WD40 PF00400.32 EGC33244.1 - 0.032 15.1 9.6 0.25 12.3 0.0 5.3 5 0 0 5 5 4 0 WD domain, G-beta repeat DUF4366 PF14283.6 EGC33244.1 - 0.1 12.6 1.4 0.2 11.7 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4366) SRP54 PF00448.22 EGC33244.1 - 0.14 11.7 0.3 2.1 8.0 0.2 2.4 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain LRR_6 PF13516.6 EGC33244.1 - 0.72 10.1 5.8 0.73 10.0 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EGC33244.1 - 1 10.1 6.3 76 4.5 0.1 4.8 3 0 0 3 3 3 0 Leucine Rich Repeat SnoaL_2 PF12680.7 EGC33246.1 - 1.8e-05 25.3 0.0 2e-05 25.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC33246.1 - 0.017 14.9 0.1 0.034 13.9 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase DUF3271 PF11675.8 EGC33246.1 - 0.023 14.0 0.2 0.028 13.7 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DUF4440 PF14534.6 EGC33246.1 - 0.095 13.1 0.0 0.11 12.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HopJ PF08888.11 EGC33246.1 - 0.1 12.8 0.0 0.15 12.3 0.0 1.4 1 0 0 1 1 1 0 HopJ type III effector protein TFIIS_C PF01096.18 EGC33247.1 - 4.3e-08 32.9 0.3 4.3e-08 32.9 0.3 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.16 EGC33247.1 - 1.4e-07 31.3 1.4 1.4e-07 31.3 1.4 2.4 3 0 0 3 3 3 1 RNA polymerases M/15 Kd subunit zf-DNA_Pol PF08996.10 EGC33247.1 - 0.0018 18.0 0.9 0.0025 17.6 0.1 1.6 2 0 0 2 2 2 1 DNA Polymerase alpha zinc finger Zn_Tnp_IS1595 PF12760.7 EGC33247.1 - 0.005 16.8 5.2 0.83 9.7 1.1 2.4 2 1 0 2 2 2 2 Transposase zinc-ribbon domain DpnI PF06044.12 EGC33247.1 - 0.026 14.2 1.1 0.037 13.7 0.2 1.7 1 1 1 2 2 2 0 Dam-replacing family C1_1 PF00130.22 EGC33247.1 - 0.026 14.4 0.1 0.026 14.4 0.1 2.3 3 0 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RRPl_C4 PF17026.5 EGC33247.1 - 0.033 14.3 1.4 0.051 13.7 1.4 1.5 1 1 0 1 1 1 0 Putative ribonucleoprotein zinc-finger pf C4 type zf-Di19 PF05605.12 EGC33247.1 - 0.037 14.3 3.7 6.2 7.2 0.1 3.2 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding zf-LITAF-like PF10601.9 EGC33247.1 - 0.15 12.3 4.3 8.1 6.8 1.7 2.6 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain Nudix_N_2 PF14803.6 EGC33247.1 - 0.2 11.6 0.5 0.2 11.6 0.5 2.8 3 0 0 3 3 3 0 Nudix N-terminal Elf1 PF05129.13 EGC33247.1 - 0.23 11.6 6.3 0.33 11.0 0.3 2.4 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like C1_2 PF03107.16 EGC33247.1 - 0.33 11.3 4.7 0.43 10.9 0.6 2.5 3 0 0 3 3 3 0 C1 domain zinc_ribbon_4 PF13717.6 EGC33247.1 - 0.36 10.8 8.6 3.9 7.5 0.2 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Trm112p PF03966.16 EGC33247.1 - 1 10.0 5.9 0.81 10.3 1.1 2.5 2 2 0 2 2 2 0 Trm112p-like protein zf-H2C2_2 PF13465.6 EGC33247.1 - 1.7 9.2 10.0 13 6.4 1.1 3.4 3 0 0 3 3 3 0 Zinc-finger double domain Ribosomal_S27e PF01667.17 EGC33247.1 - 2.3 8.0 6.9 27 4.6 0.1 3.2 3 1 0 3 3 3 0 Ribosomal protein S27 Glyco_transf_20 PF00982.21 EGC33248.1 - 6.4e-181 602.2 0.0 1e-180 601.5 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGC33248.1 - 6.9e-37 126.8 0.0 1.9e-36 125.4 0.0 1.8 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.20 EGC33248.1 - 3.6e-05 23.4 0.2 0.00036 20.1 0.2 2.4 1 1 0 1 1 1 1 Glycosyl transferases group 1 TPR_1 PF00515.28 EGC33249.1 - 1.1e-29 101.0 28.0 5.2e-08 32.4 0.8 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGC33249.1 - 4.5e-29 98.2 21.7 8.6e-07 28.6 0.1 9.0 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGC33249.1 - 2.9e-22 77.0 22.0 5.1e-07 29.4 0.1 9.1 10 0 0 10 10 9 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC33249.1 - 3.3e-22 78.5 22.3 1.1e-12 48.0 1.9 4.3 3 1 0 3 3 3 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.6 EGC33249.1 - 2.6e-15 56.8 0.2 8.9e-06 26.3 0.2 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGC33249.1 - 3.8e-14 52.7 11.2 0.002 18.4 1.4 7.7 7 2 2 9 9 9 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGC33249.1 - 1.4e-13 50.4 0.2 0.066 14.1 0.0 7.7 4 2 4 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC33249.1 - 5.3e-12 45.2 18.4 3.1e-05 23.6 0.5 7.2 5 2 4 9 9 9 4 TPR repeat TPR_6 PF13174.6 EGC33249.1 - 8.2e-11 41.8 17.7 0.041 14.5 0.0 8.5 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC33249.1 - 9.4e-11 42.1 8.5 2.5e-05 24.7 0.4 4.8 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGC33249.1 - 6.8e-10 38.6 16.6 1.7 9.2 0.0 9.2 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_9 PF13371.6 EGC33249.1 - 3.6e-06 27.0 0.3 0.06 13.5 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC33249.1 - 3.5e-05 23.5 0.6 0.063 13.3 0.1 4.5 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGC33249.1 - 0.00015 21.1 1.1 0.016 14.4 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGC33249.1 - 0.00087 19.6 1.9 0.011 16.0 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC33249.1 - 0.0023 18.0 6.1 0.08 13.0 0.0 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat NARP1 PF12569.8 EGC33249.1 - 0.0095 14.9 0.2 0.0095 14.9 0.2 2.7 4 0 0 4 4 3 1 NMDA receptor-regulated protein 1 TPR_10 PF13374.6 EGC33249.1 - 0.025 14.5 6.3 2.3 8.2 0.1 5.6 7 0 0 7 7 7 0 Tetratricopeptide repeat WD40 PF00400.32 EGC33250.1 - 6.9e-07 29.9 19.7 0.0032 18.3 0.5 5.6 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGC33250.1 - 0.11 12.5 0.2 19 5.4 0.0 3.3 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region adh_short PF00106.25 EGC33251.1 - 3e-32 111.7 0.0 4e-32 111.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33251.1 - 1.2e-20 74.1 0.0 1.4e-20 73.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33251.1 - 1.2e-07 31.8 0.0 2.3e-07 30.9 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC33251.1 - 0.095 12.1 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGC33251.1 - 0.14 12.0 0.0 0.23 11.4 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding CDO_I PF05995.12 EGC33252.1 - 1.1e-26 93.2 0.0 1.5e-26 92.7 0.0 1.1 1 0 0 1 1 1 1 Cysteine dioxygenase type I FNIP PF05725.12 EGC33253.1 - 1.3e-20 73.3 71.3 0.00039 20.5 0.7 12.6 7 5 4 12 12 12 11 FNIP Repeat zf-MYST PF17772.1 EGC33253.1 - 0.033 13.8 1.3 0.25 11.0 0.0 3.1 4 0 0 4 4 4 0 MYST family zinc finger domain DUF1319 PF07028.11 EGC33253.1 - 0.052 13.8 3.2 9.1 6.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) TbpB_C PF17483.2 EGC33253.1 - 0.15 12.4 2.6 22 5.5 0.0 3.6 4 1 0 4 4 4 0 C-lobe handle domain of Tf-binding protein B AAA_22 PF13401.6 EGC33254.1 - 8.9e-06 26.0 0.4 3.6e-05 24.1 0.4 2.0 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC33254.1 - 0.0006 20.2 0.1 0.0018 18.7 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGC33254.1 - 0.05 14.0 4.6 0.1 13.0 2.2 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC33254.1 - 0.073 13.1 0.0 2 8.4 0.0 3.1 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGC33254.1 - 0.14 12.4 0.1 0.23 11.7 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGC33254.1 - 2.6 8.5 6.8 1.1 9.6 1.1 2.7 2 1 0 2 2 2 0 AAA domain zf-MYND PF01753.18 EGC33255.1 - 6.5e-08 32.5 11.8 1.1e-07 31.8 11.8 1.4 1 0 0 1 1 1 1 MYND finger FYVE_2 PF02318.16 EGC33255.1 - 0.022 14.9 4.1 0.022 14.9 4.1 2.0 1 1 1 2 2 2 0 FYVE-type zinc finger zf-Mss51 PF13824.6 EGC33255.1 - 0.029 14.5 2.9 0.085 13.0 2.9 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 Vault PF01505.18 EGC33256.1 - 2.1e-51 171.8 0.0 8.4e-12 45.1 0.0 4.5 4 0 0 4 4 4 4 Major Vault Protein repeat domain Vault_2 PF17794.1 EGC33256.1 - 8.5e-31 106.1 0.1 1.4e-22 79.8 0.1 2.6 2 0 0 2 2 2 2 Major Vault Protein repeat domain DUF3601 PF12208.8 EGC33256.1 - 0.013 15.5 0.0 1.8 8.7 0.0 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF3601) DUF3430 PF11912.8 EGC33257.1 - 1.2e-07 32.1 33.9 4.2e-07 30.2 33.9 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) GST_C_3 PF14497.6 EGC33258.1 - 6.9e-14 51.8 0.0 1.8e-13 50.5 0.0 1.8 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC33258.1 - 2.1e-08 34.4 0.1 1e-07 32.2 0.0 2.0 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC33258.1 - 6.2e-07 29.7 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC33258.1 - 3e-05 24.1 0.0 5.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC33258.1 - 7.4e-05 22.7 0.1 0.00085 19.3 0.0 2.4 2 1 1 3 3 3 1 Glutathione S-transferase, C-terminal domain FTA4 PF13093.6 EGC33259.1 - 0.027 14.4 0.4 0.036 14.0 0.4 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 DUF4119 PF13494.6 EGC33259.1 - 0.048 13.8 2.7 0.093 12.9 2.7 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) CFAP91 PF14738.6 EGC33259.1 - 0.32 11.0 4.3 0.33 11.0 2.0 1.9 2 0 0 2 2 2 0 Cilia- and flagella-associated protein 91 Pkinase PF00069.25 EGC33260.1 - 2.4e-75 253.3 0.0 2.8e-75 253.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33260.1 - 1.7e-39 135.7 0.0 2.1e-39 135.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC33260.1 - 3e-05 23.5 0.1 5.6e-05 22.6 0.1 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC33260.1 - 0.0016 17.8 0.0 0.15 11.3 0.0 2.5 1 1 1 2 2 2 2 Kinase-like FTA2 PF13095.6 EGC33260.1 - 0.17 11.5 0.0 0.44 10.1 0.0 1.6 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Ada3 PF10198.9 EGC33261.1 - 7.5e-09 35.8 12.4 7.5e-09 35.8 12.4 3.4 4 0 0 4 4 4 1 Histone acetyltransferases subunit 3 AT_hook PF02178.19 EGC33261.1 - 0.32 11.0 3.2 1 9.4 3.2 1.9 1 0 0 1 1 1 0 AT hook motif DUF3379 PF11859.8 EGC33262.1 - 0.027 13.8 0.1 0.027 13.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3379) IKKbetaNEMObind PF12179.8 EGC33262.1 - 0.034 14.2 0.0 2.8 8.0 0.0 2.3 2 1 0 2 2 2 0 I-kappa-kinase-beta NEMO binding domain 2_5_RNA_ligase2 PF13563.6 EGC33263.1 - 7.3e-19 68.2 0.0 8.5e-19 68.0 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.9 EGC33263.1 - 7.6e-07 29.2 0.1 9.5e-07 28.9 0.1 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.16 EGC33263.1 - 9.6e-06 25.7 0.0 0.0024 18.0 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase DUF4795 PF16043.5 EGC33263.1 - 0.065 12.8 0.1 0.085 12.4 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) TPK_catalytic PF04263.16 EGC33263.1 - 0.1 12.6 0.0 0.15 12.2 0.0 1.4 1 0 0 1 1 1 0 Thiamin pyrophosphokinase, catalytic domain CPDase PF07823.11 EGC33263.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Cyclic phosphodiesterase-like protein F5_F8_type_C PF00754.25 EGC33264.1 - 4.3e-23 81.8 1.4 9.2e-23 80.7 1.1 1.7 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC33264.1 - 1.2e-21 76.7 0.4 2.9e-21 75.4 0.4 1.7 1 0 0 1 1 1 1 H-type lectin domain YqfD PF06898.11 EGC33265.1 - 0.035 12.9 0.2 0.073 11.9 0.2 1.5 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD CTD_bind PF04818.13 EGC33266.1 - 2e-06 28.5 0.4 2e-06 28.5 0.4 3.1 3 0 0 3 3 3 1 RNA polymerase II-binding domain. Dimer_Tnp_hAT PF05699.14 EGC33267.1 - 2.5e-09 36.8 1.2 3.5e-09 36.3 1.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region SNF2_N PF00176.23 EGC33268.1 - 6.5e-53 179.7 0.2 6.5e-53 179.7 0.2 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC33268.1 - 9.1e-14 51.8 1.1 1.2e-12 48.2 0.0 3.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.25 EGC33268.1 - 0.0064 16.3 13.5 0.018 14.9 13.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC33268.1 - 0.0076 16.1 10.7 0.018 14.9 10.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.6 EGC33268.1 - 0.21 11.5 5.3 0.6 10.0 5.3 1.8 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF2344 PF10105.9 EGC33268.1 - 0.22 11.3 6.2 0.068 13.0 1.5 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) zf-C3HC4_2 PF13923.6 EGC33268.1 - 0.24 11.3 11.3 0.53 10.2 11.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33268.1 - 1.1 9.4 8.6 3.2 7.9 8.6 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_2 PF13639.6 EGC33268.1 - 1.4 9.4 11.4 3.7 8.0 11.4 1.8 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.6 EGC33268.1 - 2.1 8.3 9.7 5.9 6.8 9.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 TPR_2 PF07719.17 EGC33269.1 - 0.00025 20.9 0.8 0.21 11.8 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC33269.1 - 0.0017 18.6 0.2 5.1 7.5 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC33269.1 - 0.0025 17.6 2.2 0.32 10.9 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC33269.1 - 0.011 15.9 7.7 3.7 8.0 0.0 5.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGC33269.1 - 0.025 13.8 0.1 3.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC33269.1 - 0.025 14.4 0.0 0.11 12.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.11 EGC33269.1 - 0.21 11.6 41.9 0.54 10.3 41.9 1.8 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPR PF01535.20 EGC33269.1 - 0.48 10.8 2.6 7.5 7.0 0.0 3.6 4 0 0 4 4 4 0 PPR repeat DUF4045 PF13254.6 EGC33269.1 - 0.89 9.1 29.2 1.5 8.4 29.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Telomere_reg-2 PF10193.9 EGC33269.1 - 1.1 9.7 4.5 6.9 7.2 0.8 3.2 2 2 1 3 3 3 0 Telomere length regulation protein CCSAP PF15748.5 EGC33269.1 - 5.9 7.0 27.1 15 5.7 27.1 1.7 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated EGF_Tenascin PF18720.1 EGC33270.1 - 0.0041 17.1 8.3 0.0099 15.9 8.3 1.6 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGC33270.1 - 0.3 11.5 11.8 0.64 10.4 11.8 1.6 1 0 0 1 1 1 0 EGF-like domain DUF4730 PF15873.5 EGC33271.1 - 0.00062 20.0 0.4 0.00082 19.6 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4730) RseC_MucC PF04246.12 EGC33271.1 - 0.33 10.9 2.2 0.34 10.8 2.2 1.0 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC FixS PF03597.15 EGC33271.1 - 4.3 7.1 9.5 0.26 11.0 1.6 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type PHD PF00628.29 EGC33272.1 - 1.3e-19 69.8 53.4 1.7e-11 43.8 6.7 5.2 3 1 2 5 5 5 3 PHD-finger HMG_box PF00505.19 EGC33272.1 - 4e-19 68.8 2.2 4e-19 68.8 2.2 3.6 3 0 0 3 3 3 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC33272.1 - 3.9e-16 59.4 1.0 3.9e-16 59.4 1.0 4.8 5 2 1 6 6 6 1 HMG-box domain C1_1 PF00130.22 EGC33272.1 - 0.002 18.0 5.3 0.002 18.0 5.3 6.0 3 1 3 6 6 6 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Zf_RING PF16744.5 EGC33272.1 - 0.21 11.7 39.5 1.4 9.0 2.3 4.9 2 1 1 3 3 3 0 KIAA1045 RING finger Thioredoxin PF00085.20 EGC33273.1 - 0.00011 22.1 0.0 0.00037 20.4 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin Smg8_Smg9 PF10220.9 EGC33273.1 - 0.0011 17.5 3.3 0.0016 16.8 3.3 1.3 1 0 0 1 1 1 1 Smg8_Smg9 DDE_Tnp_ISAZ013 PF07592.11 EGC33273.1 - 0.0056 15.7 7.2 0.0092 15.0 7.2 1.2 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain Thioredoxin_9 PF14595.6 EGC33273.1 - 0.016 15.0 0.5 0.037 13.8 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin TraF PF13728.6 EGC33273.1 - 0.47 10.2 0.0 0.47 10.2 0.0 2.9 1 1 2 3 3 3 0 F plasmid transfer operon protein Zip PF02535.22 EGC33273.1 - 0.6 9.3 1.6 0.77 8.9 0.6 1.6 2 0 0 2 2 2 0 ZIP Zinc transporter CSG2 PF16965.5 EGC33273.1 - 2.5 6.9 8.6 2.9 6.7 4.0 2.3 2 0 0 2 2 2 0 Ceramide synthase regulator DUF2956 PF11169.8 EGC33273.1 - 2.8 8.2 10.4 20 5.5 7.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Connexin PF00029.19 EGC33273.1 - 5.7 6.6 7.1 5.2 6.8 4.2 2.1 2 0 0 2 2 2 0 Connexin Pkinase PF00069.25 EGC33274.1 - 3.2e-77 259.5 0.0 6e-77 258.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33274.1 - 4.2e-44 150.8 0.0 7.2e-44 150.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.19 EGC33274.1 - 7.4e-18 64.1 0.0 1.3e-17 63.3 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.6 EGC33274.1 - 2e-05 24.0 0.0 4.8e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC33274.1 - 0.0016 17.9 0.0 0.0035 16.7 0.0 1.6 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC33274.1 - 0.0023 17.9 0.0 0.049 13.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family LRR_8 PF13855.6 EGC33275.1 - 1.1e-40 137.1 57.7 9.9e-11 41.2 4.0 6.0 1 1 5 6 6 6 6 Leucine rich repeat LRR_4 PF12799.7 EGC33275.1 - 1.6e-31 107.8 49.5 2.1e-06 28.0 0.7 7.7 6 1 0 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC33275.1 - 4.1e-09 36.2 19.0 0.001 18.6 2.0 4.4 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.33 EGC33275.1 - 1.9e-07 30.7 42.1 0.14 12.7 0.2 11.2 11 3 0 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.6 EGC33275.1 - 0.01 15.8 47.0 0.13 12.4 0.0 10.8 12 0 0 12 12 12 0 Leucine Rich repeat RasGEF PF00617.19 EGC33276.1 - 1e-56 191.9 1.1 5.9e-56 189.5 1.1 2.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGC33276.1 - 1.4e-12 47.8 5.4 3.1e-12 46.6 0.1 4.2 3 0 0 3 3 3 1 RasGEF N-terminal motif Drf_GBD PF06371.13 EGC33276.1 - 2.1e-12 47.0 5.3 2.1e-12 47.0 5.3 3.1 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGC33276.1 - 7.7e-05 22.4 25.9 0.0001 22.0 22.5 2.9 2 1 0 2 2 2 1 Diaphanous FH3 Domain DUF4746 PF15928.5 EGC33276.1 - 0.0046 16.4 2.8 0.0088 15.5 2.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4746) FAM176 PF14851.6 EGC33276.1 - 0.5 10.0 8.8 2.5 7.8 5.8 2.5 2 0 0 2 2 2 0 FAM176 family GOLD_2 PF13897.6 EGC33276.1 - 2.6 8.5 5.0 1 9.9 1.3 2.1 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking GCFC PF07842.12 EGC33277.1 - 1.5e-49 169.1 15.5 1.5e-49 169.1 15.5 2.3 3 0 0 3 3 3 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.8 EGC33277.1 - 1.9e-10 41.0 17.8 1.9e-10 41.0 17.8 4.2 3 2 1 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.23 EGC33277.1 - 5.9e-10 38.9 4.0 1.4e-09 37.6 4.0 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGC33277.1 - 0.00026 21.0 0.6 0.00026 21.0 0.6 4.3 5 0 0 5 5 5 1 G-patch domain HTH_3 PF01381.22 EGC33278.1 - 2.1e-15 56.5 0.1 4.8e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.7 EGC33278.1 - 2.8e-06 27.2 0.4 6.2e-06 26.1 0.1 1.6 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_31 PF13560.6 EGC33278.1 - 0.0019 18.5 0.0 0.0028 18.0 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_37 PF13744.6 EGC33278.1 - 0.022 14.7 0.2 0.039 13.9 0.1 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain Jag_N PF14804.6 EGC33278.1 - 0.062 13.6 0.1 0.15 12.4 0.0 1.7 2 0 0 2 2 2 0 Jag N-terminus DNA_pol_viral_N PF00242.17 EGC33279.1 - 0.077 12.5 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 DNA polymerase (viral) N-terminal domain DPM2 PF07297.12 EGC33280.1 - 7.3e-34 115.9 7.6 8e-34 115.8 7.6 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.12 EGC33280.1 - 3.1e-06 27.1 4.9 3.4e-06 27.0 4.9 1.0 1 0 0 1 1 1 1 PIG-P Phage_holin_Dp1 PF16938.5 EGC33280.1 - 0.041 14.1 1.5 0.041 14.1 1.5 2.3 2 1 1 3 3 3 0 Putative phage holin Dp-1 DUF2842 PF11003.8 EGC33280.1 - 0.35 11.1 8.2 0.13 12.5 2.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) LapA_dom PF06305.11 EGC33280.1 - 1.7 8.6 4.8 0.53 10.1 0.2 2.0 2 0 0 2 2 2 0 Lipopolysaccharide assembly protein A domain CSN8_PSD8_EIF3K PF10075.9 EGC33281.1 - 1.7e-24 86.4 0.6 2.8e-24 85.8 0.6 1.3 1 0 0 1 1 1 1 CSN8/PSMD8/EIF3K family SAC3_GANP PF03399.16 EGC33281.1 - 0.0043 16.5 0.7 0.0056 16.1 0.7 1.2 1 0 0 1 1 1 1 SAC3/GANP family Helitron_like_N PF14214.6 EGC33282.1 - 0.028 14.6 0.5 0.21 11.8 0.0 2.3 2 0 0 2 2 2 0 Helitron helicase-like domain at N-terminus zf-C3HC4_3 PF13920.6 EGC33284.1 - 1e-12 47.7 11.5 2e-12 46.8 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cbl_N2 PF02761.14 EGC33284.1 - 7.9e-08 32.9 3.1 7.9e-08 32.9 3.1 2.1 2 0 0 2 2 2 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 EGC33284.1 - 1.3e-07 31.6 0.0 3.8e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 SH2 domain Prok-RING_4 PF14447.6 EGC33284.1 - 0.00018 21.3 12.3 0.00033 20.4 12.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Cbl_N3 PF02762.14 EGC33284.1 - 0.00071 19.4 0.0 0.0017 18.1 0.0 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, SH2-like domain zf-C3HC4 PF00097.25 EGC33284.1 - 0.002 17.9 14.7 0.0078 16.1 14.7 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC33284.1 - 0.44 10.9 12.7 0.91 9.9 12.7 1.6 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.6 EGC33284.1 - 0.52 10.3 11.6 1.3 9.1 11.6 1.7 1 0 0 1 1 1 0 zinc-RING finger domain DUF936 PF06075.12 EGC33284.1 - 1.6 7.5 12.0 0.26 10.2 6.6 1.9 2 0 0 2 2 2 0 Plant protein of unknown function (DUF936) p450 PF00067.22 EGC33285.1 - 2.1e-68 231.2 0.0 2.5e-68 230.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 YppF PF14178.6 EGC33285.1 - 0.092 12.6 0.3 0.31 10.9 0.2 2.0 1 1 0 1 1 1 0 YppF-like protein Peptidase_S78_2 PF14550.6 EGC33285.1 - 0.11 12.6 0.0 0.23 11.6 0.0 1.5 1 0 0 1 1 1 0 Putative phage serine protease XkdF p450 PF00067.22 EGC33286.1 - 2e-64 218.0 0.0 2.3e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGC33287.1 - 8.6e-75 252.2 0.2 1e-74 252.0 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Methyltransf_7 PF03492.15 EGC33288.1 - 3.9e-56 190.7 4.4 4.9e-56 190.3 4.4 1.0 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.12 EGC33288.1 - 0.18 12.5 0.8 1.1 10.0 0.1 2.7 3 1 0 3 3 3 0 Methyltransferase domain Clat_adaptor_s PF01217.20 EGC33289.1 - 6.1e-54 181.8 1.1 7e-54 181.6 1.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.11 EGC33289.1 - 0.13 11.7 0.0 0.19 11.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) tRNA_int_endo PF01974.17 EGC33290.1 - 2.2e-19 69.3 0.1 5e-19 68.2 0.1 1.6 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain LMBR1 PF04791.16 EGC33290.1 - 5.1 5.9 8.5 6.5 5.5 8.5 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EF-hand_7 PF13499.6 EGC33291.1 - 1e-19 70.7 15.2 4.5e-08 33.4 0.4 2.9 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC33291.1 - 7.8e-19 65.9 5.6 0.00031 20.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC33291.1 - 8.5e-19 65.6 5.8 0.00021 20.6 0.2 4.2 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 EGC33291.1 - 2.2e-07 31.2 3.7 0.0043 17.4 1.7 2.9 1 1 2 3 3 3 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EGC33291.1 - 6.4e-06 25.4 6.3 2.8 7.6 0.1 4.4 4 0 0 4 4 4 3 EF hand Dimerisation PF08100.11 EGC33291.1 - 0.00076 19.4 0.0 1.6 8.9 0.0 3.3 1 1 2 3 3 3 1 Dimerisation domain Caleosin PF05042.13 EGC33291.1 - 0.0018 18.2 2.3 0.62 10.0 0.1 2.9 1 1 2 3 3 3 2 Caleosin related protein EF-hand_8 PF13833.6 EGC33291.1 - 0.0036 17.1 8.8 1.9 8.4 0.7 3.8 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_10 PF14788.6 EGC33291.1 - 0.0053 16.6 1.7 5.4 7.0 0.0 3.2 3 0 0 3 3 3 1 EF hand DUF2624 PF11116.8 EGC33291.1 - 0.011 16.6 1.3 0.011 16.6 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) RsbRD_N PF14361.6 EGC33291.1 - 0.085 13.5 0.4 0.16 12.7 0.2 1.5 2 0 0 2 2 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF2582 PF10771.9 EGC33291.1 - 0.12 12.5 0.4 0.25 11.5 0.2 1.7 1 1 1 2 2 2 0 Winged helix-turn-helix domain (DUF2582) Fe_hyd_lg_C PF02906.14 EGC33291.1 - 0.18 11.4 5.1 0.17 11.5 2.6 1.9 1 1 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain PP2C_C PF07830.13 EGC33291.1 - 0.73 10.3 4.4 3.4 8.2 1.3 2.5 2 1 1 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Ribosomal_L15e PF00827.17 EGC33292.1 - 3.9e-92 307.2 7.1 4.5e-92 307.0 7.1 1.0 1 0 0 1 1 1 1 Ribosomal L15 UBA_6 PF18039.1 EGC33292.1 - 0.017 15.0 0.0 0.03 14.3 0.0 1.3 1 0 0 1 1 1 0 UBA-like domain DUF1079 PF06435.11 EGC33292.1 - 0.2 11.9 0.0 0.39 11.0 0.0 1.4 1 0 0 1 1 1 0 Repeat of unknown function (DUF1079) SRP14 PF02290.15 EGC33293.1 - 6.9e-23 80.8 1.5 6.9e-23 80.8 1.5 1.7 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF365 PF04033.12 EGC33293.1 - 0.02 15.2 0.3 0.065 13.5 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF365) RNase_PH PF01138.21 EGC33294.1 - 2.9e-20 73.1 0.0 4.9e-20 72.4 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGC33294.1 - 4e-12 46.0 0.0 8e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-TRAF PF02176.18 EGC33296.1 - 7.1e-08 33.0 35.1 4.3e-06 27.3 1.0 4.3 3 2 1 4 4 4 3 TRAF-type zinc finger Sina PF03145.16 EGC33296.1 - 0.00047 20.1 4.2 0.00047 20.1 4.2 3.6 1 1 2 3 3 3 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC33296.1 - 0.0051 16.6 6.1 0.0051 16.6 6.1 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC33296.1 - 0.0061 17.0 29.8 0.011 16.2 7.4 3.2 2 1 1 3 3 3 2 TRAF-like zinc-finger RnlB_antitoxin PF15933.5 EGC33296.1 - 0.022 15.1 6.5 0.51 10.7 0.3 3.3 3 1 0 3 3 3 0 Antitoxin to bacterial toxin RNase LS or RnlA RGS PF00615.19 EGC33298.1 - 5.4e-28 97.6 5.0 5.4e-28 97.6 5.0 3.5 4 0 0 4 4 4 1 Regulator of G protein signaling domain LRR_1 PF00560.33 EGC33298.1 - 0.16 12.6 8.7 41 5.3 2.0 6.3 2 1 0 2 2 2 0 Leucine Rich Repeat Pyr_redox_2 PF07992.14 EGC33299.1 - 3.8e-10 39.5 0.0 1.1e-09 37.9 0.0 1.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Peptidase_M48 PF01435.18 EGC33299.1 - 6.1e-08 32.7 0.0 1.3e-07 31.6 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M48 NAD_binding_8 PF13450.6 EGC33299.1 - 2.4e-05 24.4 0.0 5.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGC33299.1 - 0.00022 20.6 0.2 0.53 9.5 0.0 3.0 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGC33299.1 - 0.008 16.6 0.0 0.99 9.9 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.17 EGC33299.1 - 0.034 13.4 0.0 0.57 9.4 0.0 2.3 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EGC33299.1 - 0.049 13.6 0.0 0.75 9.8 0.0 2.6 3 0 0 3 3 3 0 FAD-NAD(P)-binding K_oxygenase PF13434.6 EGC33299.1 - 0.05 12.7 0.0 1.1 8.4 0.0 2.3 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.14 EGC33299.1 - 0.11 11.2 0.0 0.2 10.3 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.12 EGC33299.1 - 0.18 10.8 0.0 0.29 10.2 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein GCV_H PF01597.19 EGC33300.1 - 2.3e-25 88.9 1.8 2.6e-25 88.7 1.8 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGC33300.1 - 0.067 13.0 0.1 0.11 12.4 0.1 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme YpsA PF06908.11 EGC33301.1 - 0.0082 16.2 0.1 0.023 14.7 0.1 1.7 1 1 0 1 1 1 1 YspA SLOG family DUF5024 PF16427.5 EGC33301.1 - 0.079 13.3 1.2 0.15 12.4 0.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5024) EGF_2 PF07974.13 EGC33302.1 - 0.00034 20.9 38.1 0.078 13.4 14.8 2.4 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC33302.1 - 0.22 11.7 27.2 0.9 9.7 9.8 2.3 2 0 0 2 2 2 0 Laminin EGF domain EGF_alliinase PF04863.13 EGC33302.1 - 0.74 10.3 21.8 2.5 8.6 7.1 2.9 1 1 1 2 2 2 0 Alliinase EGF-like domain EGF PF00008.27 EGC33302.1 - 1.5 9.2 30.6 0.25 11.7 12.9 2.6 2 1 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGC33303.1 - 0.00059 20.1 36.3 0.11 12.9 14.7 2.5 2 0 0 2 2 2 2 EGF-like domain EGF PF00008.27 EGC33303.1 - 0.028 14.7 26.1 0.26 11.6 7.6 2.6 2 0 0 2 2 2 0 EGF-like domain SKG6 PF08693.10 EGC33303.1 - 0.15 11.5 3.3 0.37 10.2 3.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain hEGF PF12661.7 EGC33303.1 - 0.4 11.4 21.2 3.5 8.4 7.2 2.8 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGC33303.1 - 1.6 8.9 25.1 4.6 7.5 9.0 2.5 1 1 1 2 2 2 0 Laminin EGF domain Nuc_recep-AF1 PF11825.8 EGC33303.1 - 3.4 7.7 11.3 0.11 12.6 3.5 2.6 2 0 0 2 2 2 0 Nuclear/hormone receptor activator site AF-1 ABC2_membrane PF01061.24 EGC33304.1 - 1.4e-76 256.6 58.1 7.2e-40 136.7 23.1 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC33304.1 - 8.4e-42 142.9 0.1 1.5e-20 74.1 0.0 3.1 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGC33304.1 - 1.3e-06 28.4 0.4 0.0005 20.0 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_16 PF13191.6 EGC33304.1 - 1.8e-05 25.2 0.0 0.016 15.6 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.23 EGC33304.1 - 0.00048 20.2 0.1 0.57 10.3 0.2 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGC33304.1 - 0.00049 19.8 0.9 0.011 15.4 0.3 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGC33304.1 - 0.0031 18.1 3.3 0.25 11.9 0.0 3.9 4 0 0 4 4 4 1 AAA domain AAA_22 PF13401.6 EGC33304.1 - 0.0049 17.1 0.1 0.74 10.1 0.0 3.2 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGC33304.1 - 0.0069 16.0 0.0 0.015 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.23 EGC33304.1 - 0.042 13.9 0.6 0.25 11.4 0.0 2.7 2 0 0 2 2 2 0 Dynamin family AAA_28 PF13521.6 EGC33304.1 - 0.088 13.0 0.1 0.34 11.1 0.2 1.8 2 0 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGC33304.1 - 0.14 11.9 13.2 0.42 10.4 0.0 4.2 6 0 0 6 6 6 0 AAA domain, putative AbiEii toxin, Type IV TA system Circo_capsid PF02443.15 EGC33306.1 - 0.08 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Circovirus capsid protein DUF969 PF06149.12 EGC33307.1 - 0.014 14.9 0.0 0.014 14.8 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF969) GREB1 PF15782.5 EGC33308.1 - 0.15 9.2 13.5 0.17 9.0 13.5 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer LysM PF01476.20 EGC33310.1 - 1.1e-10 41.4 0.3 0.019 15.0 0.0 3.4 3 0 0 3 3 3 3 LysM domain DPBB_1 PF03330.18 EGC33310.1 - 6e-09 36.1 0.1 2e-08 34.4 0.1 1.9 1 0 0 1 1 1 1 Lytic transglycolase DUF3024 PF11225.8 EGC33310.1 - 0.026 14.8 8.4 5.9 7.2 0.2 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3024) PSI_PsaH PF03244.14 EGC33310.1 - 0.73 9.3 4.0 36 3.9 0.1 3.4 3 0 0 3 3 3 0 Photosystem I reaction centre subunit VI Gp138_N PF18352.1 EGC33310.1 - 1.3 9.1 7.5 28 4.8 0.1 3.9 4 1 0 4 4 4 0 Phage protein Gp138 N-terminal domain GCV_H PF01597.19 EGC33311.1 - 2.2e-23 82.5 0.2 2.8e-23 82.1 0.2 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGC33311.1 - 0.021 14.7 0.1 0.13 12.1 0.1 2.0 1 1 1 2 2 2 0 Biotin-requiring enzyme GCV_H PF01597.19 EGC33312.1 - 5.2e-34 116.8 0.1 6.2e-34 116.5 0.1 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein GCV_H PF01597.19 EGC33313.1 - 2.9e-39 133.7 0.6 3.4e-39 133.5 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.22 EGC33313.1 - 0.00038 20.2 0.2 0.00056 19.7 0.2 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme F-box PF00646.33 EGC33313.1 - 0.35 10.8 1.6 0.5 10.3 1.6 1.3 1 0 0 1 1 1 0 F-box domain PPR_2 PF13041.6 EGC33314.1 - 5.7e-49 164.1 13.0 2.1e-11 43.8 0.1 9.4 3 2 7 10 10 10 8 PPR repeat family PPR_3 PF13812.6 EGC33314.1 - 1.1e-40 137.5 15.4 1.8e-10 40.8 0.1 7.1 5 2 2 7 7 7 6 Pentatricopeptide repeat domain PPR PF01535.20 EGC33314.1 - 1.2e-38 128.6 21.6 1.8e-05 24.7 0.5 12.3 12 1 0 12 12 12 7 PPR repeat PPR_1 PF12854.7 EGC33314.1 - 1.2e-32 111.3 13.0 2.4e-07 30.3 0.0 10.9 12 0 0 12 12 12 7 PPR repeat PPR_long PF17177.4 EGC33314.1 - 8.4e-26 90.6 4.9 1.5e-09 37.5 0.9 4.1 1 1 3 4 4 4 4 Pentacotripeptide-repeat region of PRORP ATP13 PF12921.7 EGC33314.1 - 3.8e-05 23.5 3.5 0.27 11.1 0.0 5.5 2 2 4 6 6 6 1 Mitochondrial ATPase expression Phage_ABA_S PF18066.1 EGC33314.1 - 0.056 14.1 0.0 7.2 7.4 0.0 3.3 2 1 1 3 3 3 0 Phage ABA sandwich domain DUF2340 PF10209.9 EGC33314.1 - 0.49 10.9 5.2 0.96 9.9 0.2 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2340) Cpn10 PF00166.21 EGC33315.1 - 1e-20 73.6 0.0 1.1e-20 73.4 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF905 PF06006.12 EGC33316.1 - 9.4e-08 31.9 5.1 21 5.2 0.0 8.8 10 0 0 10 10 10 1 Bacterial protein of unknown function (DUF905) B_lectin PF01453.24 EGC33316.1 - 1.3e-07 32.1 20.2 9.7 6.8 0.0 11.6 13 0 0 13 13 13 1 D-mannose binding lectin CoA_trans PF01144.23 EGC33316.1 - 0.045 13.1 0.0 0.094 12.1 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase ThrE_2 PF12821.7 EGC33316.1 - 1.1 9.4 4.3 8.5 6.5 0.1 4.3 6 0 0 6 6 6 0 Threonine/Serine exporter, ThrE PRMT5_TIM PF17285.2 EGC33316.1 - 1.5 7.9 6.1 3.2 6.9 0.1 3.7 4 0 0 4 4 4 0 PRMT5 TIM barrel domain HUN PF08729.10 EGC33316.1 - 3.9 7.5 7.0 8.4 6.5 0.1 3.8 4 0 0 4 4 4 0 HPC2 and ubinuclein domain Glyco_hydro_25 PF01183.20 EGC33318.1 - 1e-09 38.8 0.0 1.2e-09 38.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 DUF1815 PF08844.10 EGC33318.1 - 0.1 12.6 0.1 0.41 10.6 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1815) SNF2_N PF00176.23 EGC33319.1 - 2.1e-43 148.4 2.6 9.8e-42 142.9 0.7 2.5 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC33319.1 - 9e-15 55.0 0.3 2.7e-13 50.2 0.0 3.5 2 1 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC33319.1 - 3.6e-05 23.6 0.0 0.00015 21.6 0.0 2.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_34 PF13872.6 EGC33319.1 - 0.0002 20.4 0.1 0.00044 19.2 0.1 1.5 1 0 0 1 1 1 1 P-loop containing NTP hydrolase pore-1 DUF3290 PF11694.8 EGC33319.1 - 0.12 12.4 2.1 0.52 10.3 2.1 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Rap_GAP PF02145.15 EGC33320.1 - 1.3e-60 204.2 0.0 3.4e-60 202.8 0.0 1.8 1 0 0 1 1 1 1 Rap/ran-GAP PH PF00169.29 EGC33320.1 - 6.8e-33 113.3 11.6 4.1e-18 65.8 0.9 4.1 3 0 0 3 3 3 3 PH domain PH_11 PF15413.6 EGC33320.1 - 1.5e-13 51.1 16.7 0.00021 21.7 2.4 4.7 2 1 1 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.6 EGC33320.1 - 8.2e-07 29.1 10.3 0.012 15.7 0.6 4.1 3 1 1 4 4 4 2 PH domain PH_8 PF15409.6 EGC33320.1 - 9.5e-07 29.0 1.5 0.17 12.2 0.3 3.6 3 0 0 3 3 3 2 Pleckstrin homology domain PH_6 PF15406.6 EGC33320.1 - 2.7e-06 27.6 0.1 1.3e-05 25.4 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EGC33320.1 - 0.0015 18.3 6.7 0.62 9.9 0.2 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain PH_2 PF08458.10 EGC33320.1 - 0.0076 16.6 0.8 0.091 13.1 0.0 2.9 3 0 0 3 3 3 1 Plant pleckstrin homology-like region PH_9 PF15410.6 EGC33320.1 - 0.065 13.6 8.2 5.8 7.3 2.4 3.8 1 1 1 2 2 2 0 Pleckstrin homology domain Gp37 PF09646.10 EGC33323.1 - 0.091 12.6 0.0 0.19 11.5 0.0 1.5 1 0 0 1 1 1 0 Gp37 protein DUF5590 PF17881.1 EGC33324.1 - 0.076 13.1 0.3 0.24 11.5 0.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5590) EGF_2 PF07974.13 EGC33326.1 - 4.7e-15 55.7 91.8 2e-05 24.9 11.3 5.6 5 0 0 5 5 5 4 EGF-like domain Laminin_EGF PF00053.24 EGC33326.1 - 0.025 14.7 77.2 0.16 12.1 10.5 6.0 4 2 2 6 6 6 0 Laminin EGF domain LRR_4 PF12799.7 EGC33326.1 - 0.058 13.8 9.1 4.5 7.8 0.0 5.8 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC33326.1 - 0.15 11.8 10.2 2 8.3 0.2 4.6 5 0 0 5 5 5 0 Leucine rich repeat DUF3642 PF12182.8 EGC33326.1 - 0.24 11.7 0.1 0.24 11.7 0.1 3.7 4 0 0 4 4 4 0 Bacterial lipoprotein VP4_2 PF08935.10 EGC33326.1 - 0.28 11.8 8.7 0.31 11.7 1.3 3.6 3 0 0 3 3 3 0 Viral protein VP4 subunit EGF_Tenascin PF18720.1 EGC33326.1 - 0.36 10.9 58.7 0.019 15.0 9.2 5.3 5 0 0 5 5 5 0 Tenascin EGF domain LRR_1 PF00560.33 EGC33326.1 - 3 8.8 8.6 1.4e+02 3.7 0.1 6.1 6 0 0 6 6 6 0 Leucine Rich Repeat Pkinase_Tyr PF07714.17 EGC33327.1 - 6.7e-61 205.8 0.0 7.8e-61 205.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC33327.1 - 1e-55 189.0 0.0 1.3e-55 188.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Haspin_kinase PF12330.8 EGC33327.1 - 0.00099 18.1 0.0 0.0039 16.2 0.0 1.8 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGC33327.1 - 0.16 11.3 0.0 0.31 10.3 0.0 1.5 1 1 0 1 1 1 0 Kinase-like ABC_membrane_2 PF06472.15 EGC33328.1 - 6.6e-45 153.6 10.3 4.6e-42 144.3 2.4 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.27 EGC33328.1 - 4.9e-18 66.0 0.1 4.5e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGC33328.1 - 0.00018 21.2 0.1 0.00046 19.9 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC33328.1 - 0.00057 19.8 1.8 0.0081 16.0 0.1 2.8 2 1 0 2 2 2 1 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC33328.1 - 0.0026 18.2 0.0 0.0069 16.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGC33328.1 - 0.0074 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase T2SSE PF00437.20 EGC33328.1 - 0.012 14.7 0.0 0.02 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGC33328.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGC33328.1 - 0.019 14.5 0.1 0.076 12.5 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region DUF815 PF05673.13 EGC33328.1 - 0.019 14.1 0.0 0.032 13.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) SMC_N PF02463.19 EGC33328.1 - 0.026 14.0 0.3 0.026 14.0 0.3 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGC33328.1 - 0.033 14.7 0.0 0.72 10.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC33328.1 - 0.077 13.3 0.2 0.34 11.2 0.2 2.3 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC33328.1 - 0.17 11.6 0.1 0.55 9.9 0.1 1.8 1 1 1 2 2 2 0 IstB-like ATP binding protein AAA_30 PF13604.6 EGC33328.1 - 0.23 11.2 0.0 1.2 8.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGC33328.1 - 0.28 11.6 0.1 0.28 11.6 0.1 3.1 1 1 0 3 3 3 0 AAA domain Microtub_bind PF13931.6 EGC33328.1 - 5.2 7.5 12.2 0.6 10.5 6.9 2.0 2 0 0 2 2 2 0 Kinesin-associated microtubule-binding RSN1_7TM PF02714.15 EGC33329.1 - 8.3e-78 261.5 25.8 8.3e-78 261.5 25.8 2.7 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGC33329.1 - 5.6e-39 133.4 1.7 5.6e-39 133.4 1.7 3.4 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGC33329.1 - 1.7e-35 122.8 0.7 3e-35 122.0 0.7 1.4 1 0 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter TMEM154 PF15102.6 EGC33329.1 - 0.087 12.7 0.1 15 5.5 0.0 3.2 4 0 0 4 4 4 0 TMEM154 protein family EVC2_like PF12297.8 EGC33329.1 - 0.11 11.2 0.1 0.6 8.7 0.0 2.3 2 0 0 2 2 2 0 Ellis van Creveld protein 2 like protein Comm PF15957.5 EGC33329.1 - 0.11 12.8 7.3 2.3 8.6 0.1 3.8 3 1 0 3 3 3 0 Commissureless Endothelin PF00322.17 EGC33329.1 - 0.14 11.8 1.0 0.35 10.5 1.0 1.7 1 0 0 1 1 1 0 Endothelin family RSN1_7TM PF02714.15 EGC33330.1 - 3e-80 269.5 27.1 3e-80 269.5 27.1 2.0 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGC33330.1 - 3.9e-32 111.2 3.1 3.9e-32 111.2 3.1 3.2 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGC33330.1 - 9.6e-32 110.6 1.2 5.3e-31 108.2 1.2 2.1 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter Vpu PF00558.19 EGC33330.1 - 0.001 18.8 9.0 0.097 12.4 0.1 3.6 3 0 0 3 3 3 2 Vpu protein Phage_Gp23 PF10669.9 EGC33330.1 - 3.5 8.0 8.4 4.3 7.7 0.5 2.9 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) FNIP PF05725.12 EGC33331.1 - 0.00034 20.7 5.6 0.0081 16.3 0.3 9.0 8 2 0 8 8 8 4 FNIP Repeat SR-25 PF10500.9 EGC33331.1 - 0.0031 17.2 15.7 0.0046 16.6 15.7 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein DUF5470 PF17564.2 EGC33331.1 - 2.8 8.2 9.8 2.4 8.4 7.5 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF5470) Ssl1 PF04056.14 EGC33332.1 - 3.1e-72 242.4 0.3 4.1e-72 242.1 0.3 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.12 EGC33332.1 - 8.5e-15 54.7 11.1 8.5e-15 54.7 11.1 2.8 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.6 EGC33332.1 - 3.4e-08 34.1 0.1 9.2e-08 32.7 0.0 1.7 1 1 1 2 2 2 1 von Willebrand factor type A domain zinc_ribbon_15 PF17032.5 EGC33332.1 - 0.099 13.4 14.9 0.063 14.0 7.9 2.6 2 0 0 2 2 2 0 zinc-ribbon family FHIPEP PF00771.20 EGC33332.1 - 0.13 10.7 0.2 0.19 10.2 0.2 1.2 1 0 0 1 1 1 0 FHIPEP family DZR PF12773.7 EGC33332.1 - 8.4 6.5 18.4 1.3e+04 -3.7 18.4 3.1 1 1 0 1 1 1 0 Double zinc ribbon PAZ_siRNAbind PF12212.8 EGC33333.1 - 0.012 15.5 0.6 0.022 14.6 0.6 1.4 1 0 0 1 1 1 0 PAZ domain DUF373 PF04123.13 EGC33333.1 - 0.72 9.2 8.4 2.8 7.3 0.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) FNIP PF05725.12 EGC33335.1 - 2.7e-70 232.3 55.6 3.7e-15 55.8 0.4 8.3 3 3 7 10 10 10 10 FNIP Repeat Iso_dh PF00180.20 EGC33336.1 - 4.5e-80 269.4 0.0 5.4e-80 269.1 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 EGC33336.1 - 0.17 12.7 0.1 0.53 11.0 0.0 1.9 2 0 0 2 2 2 0 Phenylalanine zipper EGF_2 PF07974.13 EGC33337.1 - 3.3e-38 129.7 264.5 0.0004 20.7 13.1 13.8 14 0 0 14 14 14 12 EGF-like domain EGF_Tenascin PF18720.1 EGC33337.1 - 4.7e-07 29.7 191.1 0.006 16.6 9.5 13.0 12 0 0 12 12 12 8 Tenascin EGF domain Laminin_EGF PF00053.24 EGC33337.1 - 0.005 17.0 220.7 0.13 12.4 8.5 14.7 11 3 3 14 14 14 11 Laminin EGF domain VP4_2 PF08935.10 EGC33337.1 - 0.041 14.5 16.6 0.53 10.9 1.1 4.6 4 0 0 4 4 4 0 Viral protein VP4 subunit KTSC PF13619.6 EGC33337.1 - 0.058 13.2 0.0 26 4.7 0.0 3.2 2 0 0 2 2 2 0 KTSC domain DUF3430 PF11912.8 EGC33338.1 - 2.3e-25 89.9 12.3 2.3e-25 89.9 12.3 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) MIF4G PF02854.19 EGC33339.1 - 2.4e-20 73.1 17.1 2.4e-20 73.1 17.1 3.5 2 2 1 3 3 3 1 MIF4G domain Prefoldin_2 PF01920.20 EGC33339.1 - 0.0034 17.3 3.2 0.0034 17.3 3.2 5.1 3 1 1 5 5 5 1 Prefoldin subunit Tropomyosin_1 PF12718.7 EGC33339.1 - 0.011 15.9 3.7 0.011 15.9 3.7 4.1 5 0 0 5 5 5 0 Tropomyosin like TMF_DNA_bd PF12329.8 EGC33339.1 - 0.016 15.1 5.6 0.016 15.1 5.6 4.3 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding DASH_Dad2 PF08654.10 EGC33339.1 - 0.36 11.3 6.7 2.5 8.6 0.0 3.6 3 0 0 3 3 3 0 DASH complex subunit Dad2 Mto2_bdg PF12808.7 EGC33339.1 - 2.8 8.3 11.0 1.1 9.6 2.0 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF3450 PF11932.8 EGC33339.1 - 7.2 5.8 14.5 0.58 9.4 3.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UQ_con PF00179.26 EGC33340.1 - 9e-53 177.7 0.0 1e-52 177.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGC33340.1 - 0.00034 20.3 0.0 0.00039 20.1 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGC33340.1 - 0.018 15.3 0.1 0.03 14.6 0.1 1.5 1 1 0 1 1 1 0 RWD domain FA_hydroxylase PF04116.13 EGC33341.1 - 6.1e-28 97.8 16.5 6.1e-28 97.8 16.5 2.3 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Cullin_Nedd8 PF10557.9 EGC33341.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Cullin protein neddylation domain Alg14 PF08660.11 EGC33342.1 - 5.5e-57 192.5 0.0 9.4e-57 191.7 0.0 1.4 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.16 EGC33342.1 - 2.4e-23 82.9 0.0 4.4e-23 82.1 0.0 1.5 1 1 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Colipase-like PF15083.6 EGC33343.1 - 1.7e-05 24.8 1.2 2.1e-05 24.6 1.2 1.1 1 0 0 1 1 1 1 Colipase-like Nodulin_late PF07127.11 EGC33343.1 - 0.058 13.7 1.2 0.058 13.7 1.2 2.3 2 1 0 2 2 2 0 Late nodulin protein Nodulin_late PF07127.11 EGC33344.1 - 0.075 13.4 8.5 0.06 13.7 2.0 2.3 1 1 1 2 2 2 0 Late nodulin protein Laminin_EGF PF00053.24 EGC33345.1 - 4e-09 36.5 47.5 0.01 16.0 7.6 4.8 2 1 2 4 4 4 4 Laminin EGF domain EGF_2 PF07974.13 EGC33345.1 - 1.8e-06 28.2 83.2 0.014 15.8 9.9 5.4 6 0 0 6 6 6 4 EGF-like domain TIG PF01833.24 EGC33345.1 - 1.5e-05 25.0 16.6 0.002 18.2 0.4 4.5 4 0 0 4 4 4 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC33346.1 - 2.4e-07 30.8 47.1 0.01 16.0 7.6 4.8 3 1 1 4 4 4 4 Laminin EGF domain TIG PF01833.24 EGC33346.1 - 1.3e-06 28.3 13.7 0.0011 19.0 0.2 4.7 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 EGC33346.1 - 4.7e-06 26.9 81.4 0.022 15.1 12.6 5.4 6 0 0 6 6 6 4 EGF-like domain AAA_5 PF07728.14 EGC33347.1 - 1.3e-116 384.8 0.3 4.3e-22 78.6 0.0 10.1 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_lid_7 PF17867.1 EGC33347.1 - 3.1e-53 178.4 4.5 1.1e-16 60.9 0.2 6.9 6 0 0 6 6 6 4 Midasin AAA lid domain AAA_lid_5 PF17865.1 EGC33347.1 - 1.4e-32 111.9 0.0 7.4e-32 109.6 0.0 2.4 1 0 0 1 1 1 1 Midasin AAA lid domain AAA_3 PF07726.11 EGC33347.1 - 4.6e-30 104.2 0.0 1.1e-10 41.4 0.0 6.6 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.29 EGC33347.1 - 7.2e-24 84.7 0.1 0.00029 21.3 0.0 7.9 6 0 0 6 6 6 4 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGC33347.1 - 8.3e-24 84.1 8.9 4.2e-06 26.4 0.2 7.3 6 0 0 6 6 6 5 P-loop containing dynein motor region AAA_16 PF13191.6 EGC33347.1 - 1.5e-21 77.5 2.3 7.5e-05 23.2 0.0 7.6 6 1 0 6 6 6 4 AAA ATPase domain Dynein_heavy PF03028.15 EGC33347.1 - 4.9e-20 71.8 0.0 0.005 16.9 0.0 7.7 7 0 0 7 7 6 5 Dynein heavy chain region D6 P-loop domain AAA_14 PF13173.6 EGC33347.1 - 7.1e-16 58.4 6.0 0.0037 17.3 0.0 8.5 9 0 0 9 9 7 4 AAA domain Sigma54_activat PF00158.26 EGC33347.1 - 6.5e-15 55.2 0.0 0.043 13.5 0.0 5.9 5 0 0 5 5 5 4 Sigma-54 interaction domain AAA_22 PF13401.6 EGC33347.1 - 1.2e-13 51.5 4.3 0.0093 16.2 0.0 7.8 7 0 0 7 7 6 2 AAA domain AAA_6 PF12774.7 EGC33347.1 - 4.8e-12 45.5 1.2 0.56 9.1 0.0 8.1 8 1 0 8 8 8 3 Hydrolytic ATP binding site of dynein motor region T2SSE PF00437.20 EGC33347.1 - 1.3e-10 40.8 5.2 0.059 12.4 0.0 6.0 6 0 0 6 6 6 2 Type II/IV secretion system protein TsaE PF02367.17 EGC33347.1 - 6.7e-10 39.0 6.9 0.73 9.8 0.0 6.7 7 0 0 7 7 6 4 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGC33347.1 - 7e-10 38.5 0.3 0.019 14.3 0.0 5.1 5 0 0 5 5 4 2 Zeta toxin AAA_33 PF13671.6 EGC33347.1 - 7.8e-10 39.1 0.2 1.4 9.0 0.0 5.6 4 1 0 4 4 4 2 AAA domain Sigma54_activ_2 PF14532.6 EGC33347.1 - 4.2e-08 33.4 1.5 0.21 11.7 0.0 6.3 5 0 0 5 5 5 2 Sigma-54 interaction domain AAA_18 PF13238.6 EGC33347.1 - 4.8e-08 33.6 22.6 0.046 14.3 0.1 9.0 7 0 0 7 7 5 3 AAA domain AAA_30 PF13604.6 EGC33347.1 - 9.6e-08 32.0 0.0 0.079 12.7 0.0 5.7 6 0 0 6 6 6 1 AAA domain NACHT PF05729.12 EGC33347.1 - 4.4e-06 26.7 3.1 3.1 7.7 0.1 5.5 6 0 0 6 6 5 2 NACHT domain RuvB_N PF05496.12 EGC33347.1 - 5.9e-06 26.1 1.2 1.5 8.6 0.0 6.2 7 0 0 7 7 6 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGC33347.1 - 7.8e-06 26.2 3.9 3.7 7.8 0.0 5.6 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EGC33347.1 - 1.6e-05 24.6 3.5 12 5.8 0.0 6.0 6 0 0 6 6 6 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGC33347.1 - 2.9e-05 24.4 7.4 1.5 9.2 0.0 7.3 8 0 0 8 8 5 1 RNA helicase PduV-EutP PF10662.9 EGC33347.1 - 0.00013 21.7 4.1 3.8 7.3 0.1 5.6 5 0 0 5 5 5 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGC33347.1 - 0.00013 21.9 6.4 3.7 7.4 0.1 5.5 5 0 0 5 5 5 1 RsgA GTPase IstB_IS21 PF01695.17 EGC33347.1 - 0.0002 21.1 0.0 8.1 6.1 0.0 4.8 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_19 PF13245.6 EGC33347.1 - 0.001 19.4 3.6 11 6.3 0.0 5.3 6 0 0 6 6 4 0 AAA domain Viral_helicase1 PF01443.18 EGC33347.1 - 0.0018 18.1 0.1 3.8 7.2 0.0 3.5 3 0 0 3 3 2 1 Viral (Superfamily 1) RNA helicase cobW PF02492.19 EGC33347.1 - 0.0038 16.8 1.2 11 5.5 0.0 4.2 4 0 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.22 EGC33347.1 - 0.005 16.5 2.8 15 5.1 0.0 4.9 6 0 0 6 6 5 0 SRP54-type protein, GTPase domain CPT PF07931.12 EGC33347.1 - 0.0053 16.6 0.8 4 7.2 0.0 4.9 4 1 0 4 4 4 1 Chloramphenicol phosphotransferase-like protein Roc PF08477.13 EGC33347.1 - 0.012 15.8 3.0 13 6.0 0.0 5.3 5 0 0 5 5 5 0 Ras of Complex, Roc, domain of DAPkinase AAA_25 PF13481.6 EGC33347.1 - 0.013 15.0 0.6 33 4.0 0.0 4.8 6 0 0 6 6 6 0 AAA domain IPT PF01745.16 EGC33347.1 - 0.027 13.9 1.4 21 4.4 0.0 5.0 5 0 0 5 5 5 0 Isopentenyl transferase NTPase_1 PF03266.15 EGC33347.1 - 0.064 13.2 7.4 15 5.4 0.2 4.9 4 0 0 4 4 4 0 NTPase MMR_HSR1 PF01926.23 EGC33347.1 - 0.2 11.8 2.9 6.6 6.9 0.2 4.5 5 0 0 5 5 4 0 50S ribosome-binding GTPase Got1 PF04178.12 EGC33349.1 - 2.7e-28 98.6 21.1 3.9e-28 98.1 20.8 1.3 1 1 0 1 1 1 1 Got1/Sft2-like family ATP-synt_B PF00430.18 EGC33349.1 - 0.55 10.3 4.2 0.68 10.0 0.1 2.3 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) TMCO5 PF14992.6 EGC33349.1 - 3.3 7.2 5.6 7 6.1 0.1 2.2 2 0 0 2 2 2 0 TMCO5 family Ribosomal_L7Ae PF01248.26 EGC33350.1 - 3.1e-12 46.0 0.2 8.9e-12 44.6 0.2 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF668 PF05003.12 EGC33350.1 - 9.3 6.8 7.4 6.7 7.3 3.6 2.8 3 1 0 3 3 3 0 Protein of unknown function (DUF668) Nrap_D3 PF17404.2 EGC33351.1 - 5.4e-44 150.1 0.1 1.8e-43 148.4 0.1 2.0 1 0 0 1 1 1 1 Nrap protein domain 3 Nrap PF03813.14 EGC33351.1 - 9.2e-39 132.9 7.4 9.2e-39 132.9 7.4 2.1 2 0 0 2 2 2 1 Nrap protein domain 1 Nrap_D5 PF17406.2 EGC33351.1 - 3.4e-36 124.4 3.3 9e-35 119.8 0.1 2.8 3 0 0 3 3 3 2 Nrap protein PAP/OAS1-like domain 5 Nrap_D4 PF17405.2 EGC33351.1 - 8.9e-29 100.4 0.2 2e-28 99.2 0.2 1.5 1 0 0 1 1 1 1 Nrap protein nucleotidyltransferase domain 4 Nrap_D6 PF17407.2 EGC33351.1 - 7.5e-27 94.2 4.2 7.5e-27 94.2 4.2 2.3 2 0 0 2 2 2 1 Nrap protein domain 6 Nrap_D2 PF17403.2 EGC33351.1 - 1.3e-24 86.6 1.2 1.3e-24 86.6 1.2 3.1 2 1 2 4 4 4 1 Nrap protein PAP/OAS-like domain adh_short PF00106.25 EGC33352.1 - 4.1e-40 137.3 1.2 7.4e-40 136.5 1.2 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33352.1 - 6.1e-34 117.6 0.9 1.3e-32 113.2 0.1 2.1 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase SCP2 PF02036.17 EGC33352.1 - 3.1e-26 91.8 0.3 5.9e-26 90.9 0.3 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.10 EGC33352.1 - 3.3e-16 59.7 0.4 6.9e-16 58.7 0.4 1.4 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.6 EGC33352.1 - 5.2e-05 23.5 0.1 8.7e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal DUF3235 PF11574.8 EGC33352.1 - 0.078 13.8 1.4 0.43 11.5 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3235) Myb_DNA-binding PF00249.31 EGC33353.1 - 6.8e-34 115.8 3.9 6.4e-14 51.9 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC33353.1 - 1.7e-22 79.4 15.3 2.3e-07 30.9 0.6 4.2 5 0 0 5 5 5 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGC33353.1 - 3.2e-06 27.1 2.9 1.2 9.1 0.0 3.3 1 1 2 3 3 3 3 SLIDE Myb_DNA-bind_7 PF15963.5 EGC33353.1 - 0.017 15.0 8.0 0.1 12.5 1.2 2.9 3 0 0 3 3 3 0 Myb DNA-binding like dCache_1 PF02743.18 EGC33354.1 - 0.0089 15.8 4.3 0.01 15.6 4.3 1.1 1 0 0 1 1 1 1 Cache domain AAA_23 PF13476.6 EGC33354.1 - 0.017 15.6 7.9 0.021 15.4 7.9 1.0 1 0 0 1 1 1 0 AAA domain SpoIISA_toxin PF14171.6 EGC33354.1 - 0.07 12.8 3.5 0.078 12.7 3.5 1.0 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4663 PF15668.5 EGC33354.1 - 0.24 10.4 0.7 0.29 10.1 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4663) VCBS PF13517.6 EGC33355.1 - 4.5e-16 59.2 26.4 8.8e-08 32.6 4.3 5.8 5 0 0 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGC33355.1 - 1.7e-09 37.6 20.6 0.0057 16.8 0.5 6.1 6 0 0 6 6 6 4 FG-GAP repeat PQQ_2 PF13360.6 EGC33355.1 - 5.3e-06 26.2 0.0 0.051 13.1 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.21 EGC33355.1 - 0.0002 21.1 4.3 0.16 12.0 0.1 5.2 5 0 0 5 5 5 1 PQQ enzyme repeat PQQ_3 PF13570.6 EGC33355.1 - 0.0011 19.4 2.9 7.1 7.3 0.1 5.0 5 0 0 5 5 5 1 PQQ-like domain BBS2_Mid PF14783.6 EGC33355.1 - 0.0021 18.1 3.0 22 5.1 0.1 5.5 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region TcdB_toxin_midN PF12256.8 EGC33355.1 - 0.043 13.2 7.4 0.39 10.1 0.0 4.7 6 0 0 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region GramPos_pilinD3 PF16570.5 EGC33355.1 - 0.053 14.2 0.2 0.35 11.6 0.1 2.3 2 0 0 2 2 2 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain Itfg2 PF15907.5 EGC33355.1 - 0.31 10.0 13.3 12 4.8 0.0 5.5 6 1 1 7 7 7 0 Integrin-alpha FG-GAP repeat-containing protein 2 RabGAP-TBC PF00566.18 EGC33356.1 - 1.2e-07 31.7 15.1 1.2e-07 31.7 15.1 3.6 3 1 0 3 3 3 1 Rab-GTPase-TBC domain DUF3601 PF12208.8 EGC33356.1 - 0.21 11.7 2.2 22 5.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3601) Sec61_beta PF03911.16 EGC33357.1 - 2.6e-14 52.9 0.7 2.9e-14 52.8 0.7 1.1 1 0 0 1 1 1 1 Sec61beta family PARP PF00644.20 EGC33358.1 - 1.5e-63 214.0 1.4 7.7e-62 208.4 0.0 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC33358.1 - 1.2e-41 142.0 4.5 2.7e-41 140.8 3.2 2.2 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGC33358.1 - 1.3e-17 63.6 0.3 3.2e-17 62.4 0.3 1.7 1 0 0 1 1 1 1 WGR domain PADR1 PF08063.12 EGC33358.1 - 4.1e-16 58.5 0.4 1e-15 57.2 0.4 1.7 1 0 0 1 1 1 1 PADR1 (NUC008) domain zf-PARP PF00645.18 EGC33358.1 - 6e-09 36.6 3.2 6e-09 36.6 3.2 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region BRCT PF00533.26 EGC33358.1 - 6.5e-07 29.6 0.1 4.2e-06 27.0 0.1 2.5 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC33358.1 - 3.9e-05 24.0 0.1 0.00069 20.0 0.1 2.8 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain SwrA PF17423.2 EGC33358.1 - 0.031 14.2 0.0 0.54 10.3 0.0 2.8 2 0 0 2 2 2 0 Swarming motility protein DUF2201_N PF13203.6 EGC33358.1 - 0.14 11.8 0.2 0.23 11.0 0.2 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DiS_P_DiS PF06750.13 EGC33358.1 - 0.49 10.5 2.5 2.7 8.2 0.0 3.1 4 0 0 4 4 4 0 Bacterial Peptidase A24 N-terminal domain NDUFA12 PF05071.16 EGC33359.1 - 5.5e-26 91.2 0.1 6.9e-26 90.9 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PIP5K PF01504.18 EGC33360.1 - 2.2e-94 315.8 9.6 2.2e-94 315.8 9.6 3.0 2 2 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PP2C_C PF07830.13 EGC33360.1 - 0.87 10.1 6.3 4.5 7.8 0.3 2.7 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain OmpH PF03938.14 EGC33360.1 - 8.8 6.7 18.4 0.87 9.9 6.6 3.6 4 0 0 4 4 4 0 Outer membrane protein (OmpH-like) FAD_binding_3 PF01494.19 EGC33361.1 - 7.2e-23 81.4 0.0 3.1e-11 43.1 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain SE PF08491.10 EGC33361.1 - 3.4e-07 29.6 0.1 8.9e-07 28.2 0.1 1.6 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.14 EGC33361.1 - 7.3e-06 25.1 0.0 0.00018 20.5 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.12 EGC33361.1 - 6.5e-05 22.1 0.0 0.0069 15.5 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.24 EGC33361.1 - 0.00093 18.9 0.0 0.0014 18.2 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC33361.1 - 0.015 15.5 0.0 0.035 14.3 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.14 EGC33361.1 - 0.028 13.7 0.0 0.071 12.3 0.0 1.7 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC33361.1 - 0.034 14.7 0.0 0.096 13.3 0.0 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC33361.1 - 0.05 12.9 0.0 0.15 11.2 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.6 EGC33361.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 FAD-NAD(P)-binding NAD_Gly3P_dh_N PF01210.23 EGC33361.1 - 0.12 12.4 0.1 0.23 11.4 0.1 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pkinase PF00069.25 EGC33362.1 - 7e-57 192.8 0.1 9.7e-57 192.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33362.1 - 1.5e-28 99.8 0.0 2.4e-28 99.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGC33362.1 - 6.3e-05 22.7 0.1 0.00012 21.8 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Pkinase_fungal PF17667.1 EGC33362.1 - 0.00057 18.8 0.0 0.00087 18.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase PMR5N PF14416.6 EGC33362.1 - 0.009 16.3 3.2 0.011 16.0 1.9 1.8 2 0 0 2 2 2 1 PMR5 N terminal Domain APH PF01636.23 EGC33362.1 - 0.015 15.2 0.0 0.023 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kinase-like PF14531.6 EGC33362.1 - 0.14 11.4 0.0 0.25 10.6 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.25 EGC33363.1 - 4.5e-52 177.0 0.1 6.4e-52 176.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33363.1 - 4.8e-29 101.4 0.0 7e-29 100.9 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC33363.1 - 2.8e-05 23.1 0.0 3.8e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase APH PF01636.23 EGC33363.1 - 0.00089 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC33363.1 - 0.0011 18.6 0.1 0.0023 17.6 0.1 1.7 1 1 1 2 2 2 1 RIO1 family Kinase-like PF14531.6 EGC33363.1 - 0.0019 17.6 0.0 0.0024 17.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC33363.1 - 0.0035 16.7 0.1 0.0056 16.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC33363.1 - 0.0086 15.1 0.8 0.011 14.7 0.8 1.1 1 0 0 1 1 1 1 Haspin like kinase domain ACDC PF14733.6 EGC33363.1 - 0.025 14.9 0.2 0.077 13.3 0.0 1.8 1 1 1 2 2 2 0 AP2-coincident C-terminal N_Asn_amidohyd PF14736.6 EGC33363.1 - 0.16 11.1 0.0 0.2 10.8 0.0 1.1 1 0 0 1 1 1 0 Protein N-terminal asparagine amidohydrolase Pkinase PF00069.25 EGC33364.1 - 9.8e-59 198.9 0.0 1.4e-58 198.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33364.1 - 1.1e-30 106.8 0.0 1.5e-30 106.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC33364.1 - 8.8e-07 28.5 0.0 1.3e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC33364.1 - 3.7e-05 23.8 0.0 5.4e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC33364.1 - 0.00016 20.6 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Fungal protein kinase RIO1 PF01163.22 EGC33364.1 - 0.00022 20.9 0.1 0.00038 20.1 0.1 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGC33364.1 - 0.0011 18.3 0.0 0.002 17.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC33364.1 - 0.054 13.1 0.1 0.096 12.3 0.1 1.5 1 1 0 1 1 1 0 Kinetochore Sim4 complex subunit FTA2 SapB_1 PF05184.15 EGC33365.1 - 3.8e-24 84.3 18.0 2.6e-12 46.5 6.1 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGC33365.1 - 4.1e-17 62.0 8.0 1.1e-11 44.6 1.5 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 2 Uteroglobin PF01099.17 EGC33365.1 - 0.088 13.2 3.4 0.29 11.5 0.5 2.6 2 2 0 2 2 2 0 Uteroglobin family WD40 PF00400.32 EGC33367.1 - 4.1e-11 43.2 15.8 0.0021 18.8 0.1 5.2 5 1 0 5 5 5 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC33367.1 - 5.7e-11 42.6 0.9 0.0057 16.9 0.1 3.6 3 0 0 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain SnoaL_2 PF12680.7 EGC33367.1 - 0.02 15.5 0.1 0.057 14.1 0.1 1.8 1 0 0 1 1 1 0 SnoaL-like domain DPPIV_N PF00930.21 EGC33367.1 - 0.096 11.4 5.6 1.1 7.9 1.5 2.7 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region IKI3 PF04762.12 EGC33367.1 - 0.24 9.3 3.4 1.4 6.8 1.2 2.1 1 1 0 2 2 2 0 IKI3 family DUF676 PF05057.14 EGC33368.1 - 8.5e-38 130.1 1.2 1.5e-37 129.2 0.6 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.8 EGC33368.1 - 2.2e-17 63.4 0.1 2.2e-17 63.4 0.1 3.6 3 0 0 3 3 3 1 Protein FAM135 PGAP1 PF07819.13 EGC33368.1 - 2.7e-06 27.3 0.8 2.7e-06 27.3 0.8 2.9 3 1 0 3 3 3 1 PGAP1-like protein Lipase_3 PF01764.25 EGC33368.1 - 0.0045 16.8 0.1 0.01 15.7 0.1 1.6 1 0 0 1 1 1 1 Lipase (class 3) Carbpep_Y_N PF05388.11 EGC33368.1 - 0.012 16.2 0.8 0.012 16.2 0.8 2.9 3 0 0 3 3 3 0 Carboxypeptidase Y pro-peptide Hydrolase_4 PF12146.8 EGC33368.1 - 0.035 13.4 0.0 0.1 11.9 0.0 1.7 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DUF829 PF05705.14 EGC33369.1 - 1.8e-42 145.9 1.0 4e-42 144.8 1.0 1.5 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF4271 PF14093.6 EGC33369.1 - 0.17 11.8 4.0 0.28 11.1 4.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4271) Glyco_hydro_35 PF01301.19 EGC33370.1 - 1.7e-95 320.3 2.8 1.7e-95 320.3 2.8 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 GHD PF17834.1 EGC33370.1 - 0.039 14.0 0.0 0.12 12.5 0.0 1.9 1 0 0 1 1 1 0 Beta-sandwich domain in beta galactosidase Orthoreo_P17 PF07272.11 EGC33371.1 - 0.093 12.7 0.5 0.17 11.9 0.1 1.6 2 0 0 2 2 2 0 Orthoreovirus P17 protein LAMTOR PF15454.6 EGC33371.1 - 0.32 11.6 11.6 0.15 12.7 6.9 2.6 2 1 0 2 2 2 0 Late endosomal/lysosomal adaptor and MAPK and MTOR activator DUF1713 PF08213.11 EGC33373.1 - 3.7e-12 45.9 21.6 5.3e-12 45.4 21.6 1.3 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Myb_Cef PF11831.8 EGC33373.1 - 0.0092 15.6 1.1 0.014 15.0 1.1 1.2 1 0 0 1 1 1 1 pre-mRNA splicing factor component DUF3439 PF11921.8 EGC33373.1 - 0.48 10.4 5.5 0.8 9.7 5.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CBM49 PF09478.10 EGC33374.1 - 2.6e-18 66.1 4.6 5.1e-18 65.2 4.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 dCMP_cyt_deam_1 PF00383.23 EGC33374.1 - 2.6e-11 43.3 0.4 4.8e-11 42.4 0.4 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGC33374.1 - 1.2e-10 41.2 0.2 1.9e-10 40.6 0.2 1.2 1 0 0 1 1 1 1 MafB19-like deaminase HPIP_like PF18524.1 EGC33374.1 - 0.0065 16.2 2.0 0.0087 15.8 0.1 2.2 2 0 0 2 2 2 1 High potential iron-sulfur protein like Bd3614-deam PF14439.6 EGC33374.1 - 0.012 15.6 0.3 1.6 8.8 0.3 2.3 1 1 0 1 1 1 0 Bd3614-like deaminase Nuf2 PF03800.14 EGC33375.1 - 1.8e-27 96.1 0.0 1.8e-27 96.1 0.0 3.5 3 1 0 3 3 3 1 Nuf2 family DHR10 PF18595.1 EGC33375.1 - 0.00034 20.7 17.1 0.00034 20.7 17.1 4.7 1 1 3 4 4 4 2 Designed helical repeat protein 10 domain YbaJ PF10757.9 EGC33375.1 - 0.014 15.9 2.6 0.014 15.9 2.6 2.8 3 0 0 3 3 3 0 Biofilm formation regulator YbaJ Pkinase PF00069.25 EGC33376.1 - 8.3e-71 238.4 0.1 9.9e-71 238.2 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33376.1 - 9.3e-34 116.9 0.0 1.1e-33 116.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC33376.1 - 2.2e-10 40.3 0.0 2.8e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC33376.1 - 9.1e-06 25.2 0.0 1.4e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC33376.1 - 0.066 13.1 0.0 0.093 12.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Mt_ATP-synt_D PF05873.12 EGC33377.1 - 1.9e-05 24.5 2.9 2.8e-05 24.0 2.9 1.2 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) TetR_C_5 PF08360.11 EGC33377.1 - 0.053 13.7 3.6 0.11 12.7 3.6 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region FAS_N PF17828.1 EGC33377.1 - 0.11 12.5 0.9 0.45 10.5 0.5 2.1 1 1 1 2 2 2 0 N-terminal domain in fatty acid synthase subunit beta DUF2852 PF11014.8 EGC33377.1 - 0.19 11.9 3.4 0.068 13.3 0.8 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PhoPQ_related PF10142.9 EGC33378.1 - 7.3e-122 406.5 3.1 8.6e-122 406.3 3.1 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF669 PF05037.13 EGC33379.1 - 0.15 12.2 4.1 0.32 11.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF669) Acetyltransf_1 PF00583.25 EGC33380.1 - 4.9e-09 36.5 0.0 6.1e-09 36.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC33380.1 - 1.7e-07 31.6 0.0 2.3e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC33380.1 - 2.2e-07 30.9 0.0 2.5e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC33380.1 - 1.2e-06 28.4 0.0 1.9e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.7 EGC33380.1 - 0.00069 19.7 0.2 0.0019 18.3 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain SOR PF07682.11 EGC33380.1 - 0.062 12.2 0.0 0.062 12.2 0.0 1.0 1 0 0 1 1 1 0 Sulphur oxygenase reductase SPOR PF05036.13 EGC33380.1 - 0.18 12.2 0.0 0.3 11.5 0.0 1.4 1 0 0 1 1 1 0 Sporulation related domain FNIP PF05725.12 EGC33381.1 - 8.1e-23 80.3 43.9 6.2e-10 39.1 1.7 9.1 7 3 2 9 9 9 5 FNIP Repeat WD40 PF00400.32 EGC33382.1 - 1.3e-16 60.6 8.7 1.1e-05 26.1 0.3 3.3 3 0 0 3 3 3 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC33382.1 - 6.2e-06 26.4 0.6 0.062 13.6 1.3 2.7 1 1 2 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain Nucleoporin_N PF08801.11 EGC33382.1 - 0.086 11.6 0.2 0.69 8.6 0.1 1.9 1 1 1 2 2 2 0 Nup133 N terminal like UT PF03253.14 EGC33383.1 - 3e-55 187.4 24.7 3.4e-55 187.2 24.7 1.0 1 0 0 1 1 1 1 Urea transporter Ndc1_Nup PF09531.10 EGC33384.1 - 0.00074 18.3 0.0 0.00074 18.3 0.0 4.2 2 2 1 4 4 4 2 Nucleoporin protein Ndc1-Nup Beta_helix PF13229.6 EGC33385.1 - 2e-22 79.7 59.3 3.8e-11 43.1 11.3 4.1 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.13 EGC33385.1 - 6.2e-11 42.0 23.4 2.6e-09 36.7 8.3 4.2 2 1 2 4 4 4 2 Periplasmic copper-binding protein (NosD) End_N_terminal PF12218.8 EGC33385.1 - 0.0019 17.9 0.0 0.0046 16.6 0.0 1.7 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Dzip-like_N PF13815.6 EGC33386.1 - 1.3e-17 63.8 4.8 1.3e-17 63.8 4.8 8.7 5 3 2 7 7 7 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-RING_2 PF13639.6 EGC33387.1 - 2.8e-09 37.1 12.7 5.6e-09 36.2 12.7 1.5 1 0 0 1 1 1 1 Ring finger domain TFIIA PF03153.13 EGC33387.1 - 6.8e-08 32.9 41.1 6.8e-08 32.9 41.1 2.2 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.6 EGC33387.1 - 2.4e-06 27.3 8.7 4.2e-06 26.5 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33387.1 - 2.4e-06 27.7 8.3 6.8e-06 26.3 8.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC33387.1 - 9.3e-06 25.4 11.3 2e-05 24.3 11.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33387.1 - 4.2e-05 23.3 13.7 0.00011 22.0 13.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC33387.1 - 0.0027 17.8 5.2 0.006 16.7 5.2 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EGC33387.1 - 0.014 15.3 11.9 0.014 15.3 11.9 1.8 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC33387.1 - 0.019 15.1 12.2 0.049 13.8 12.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC33387.1 - 0.021 14.6 10.5 0.14 12.0 10.6 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC33387.1 - 0.043 13.9 2.9 0.095 12.8 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger ATP-synt_8 PF00895.20 EGC33387.1 - 0.06 13.8 0.5 0.06 13.8 0.5 3.5 3 0 0 3 3 2 0 ATP synthase protein 8 DUF4064 PF13273.6 EGC33387.1 - 0.22 11.8 0.0 0.64 10.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) MCD PF05292.11 EGC33387.1 - 0.3 10.6 5.3 1.1 8.7 2.8 2.3 1 1 1 2 2 2 0 Malonyl-CoA decarboxylase C-terminal domain zf-RING_UBOX PF13445.6 EGC33387.1 - 1.1 9.3 10.4 3.2 7.9 10.4 1.9 1 0 0 1 1 1 0 RING-type zinc-finger CAF-1_p150 PF11600.8 EGC33387.1 - 1.4 8.6 33.9 0.024 14.3 26.2 1.9 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_11 PF17123.5 EGC33387.1 - 2.7 7.8 9.4 5.1 6.9 9.4 1.5 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC33387.1 - 4 7.1 8.7 7.1 6.3 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Kinesin PF00225.23 EGC33388.1 - 5.4e-113 377.3 1.0 5.4e-113 377.3 1.0 3.0 3 1 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGC33388.1 - 1.1e-32 113.0 0.1 1.1e-32 113.0 0.1 4.0 4 0 0 4 4 4 1 Microtubule binding Spc7 PF08317.11 EGC33388.1 - 2.1 7.2 65.6 0.53 9.1 11.6 4.4 4 0 0 4 4 4 0 Spc7 kinetochore protein Cullin PF00888.22 EGC33390.1 - 3.9e-26 91.8 11.7 3.9e-26 91.8 11.7 3.2 2 1 1 3 3 3 1 Cullin family ANAPC2 PF08672.11 EGC33390.1 - 1.2e-18 67.3 1.5 1.2e-18 67.3 1.5 3.1 3 0 0 3 3 3 1 Anaphase promoting complex (APC) subunit 2 Pox_Ag35 PF03286.14 EGC33390.1 - 0.84 9.4 12.5 0.5 10.1 4.2 2.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein SDA1 PF05285.12 EGC33390.1 - 4.1 6.7 14.9 0.33 10.3 6.8 2.4 2 0 0 2 2 2 0 SDA1 HAND PF09110.11 EGC33390.1 - 7.5 7.3 17.8 5.8 7.7 5.9 3.5 3 0 0 3 3 3 0 HAND Lon_C PF05362.13 EGC33391.1 - 3.2e-58 196.7 0.0 7.1e-58 195.5 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGC33391.1 - 1.1e-25 90.6 0.0 3.2e-25 89.1 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGC33391.1 - 1.3e-06 28.7 0.0 4.7e-06 26.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGC33391.1 - 2.9e-06 27.3 0.0 6.3e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGC33391.1 - 6.5e-06 26.0 0.1 2.3e-05 24.2 0.1 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC33391.1 - 1.7e-05 25.1 0.5 0.0015 18.8 0.2 3.2 2 1 0 2 2 2 1 AAA domain MCM PF00493.23 EGC33391.1 - 5.6e-05 22.3 0.6 0.00024 20.3 0.1 2.3 3 0 0 3 3 3 1 MCM P-loop domain ChlI PF13541.6 EGC33391.1 - 6.6e-05 22.8 0.0 0.00013 21.8 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase AAA_16 PF13191.6 EGC33391.1 - 7.7e-05 23.1 0.1 0.00089 19.7 0.1 2.3 1 1 1 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EGC33391.1 - 0.0003 20.1 0.1 0.0003 20.1 0.1 2.7 3 0 0 3 3 3 1 TIP49 P-loop domain AAA_14 PF13173.6 EGC33391.1 - 0.0029 17.6 3.7 0.0085 16.1 0.0 3.4 2 1 2 4 4 4 1 AAA domain AAA_7 PF12775.7 EGC33391.1 - 0.003 17.1 0.3 0.015 14.8 0.0 2.1 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGC33391.1 - 0.0059 16.5 0.0 0.026 14.4 0.0 2.2 2 1 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGC33391.1 - 0.0065 17.0 0.0 0.0065 17.0 0.0 4.0 3 1 1 4 4 3 1 AAA domain AAA_30 PF13604.6 EGC33391.1 - 0.02 14.6 0.0 0.043 13.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC33391.1 - 0.043 13.6 0.0 0.083 12.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF1493 PF07377.12 EGC33391.1 - 0.05 14.1 1.0 0.21 12.0 1.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) AAA_19 PF13245.6 EGC33391.1 - 0.052 13.9 0.1 0.24 11.7 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC33391.1 - 0.074 13.2 0.0 0.19 11.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGC33391.1 - 0.095 12.1 0.3 0.27 10.6 0.1 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGC33391.1 - 0.15 12.5 0.1 0.15 12.5 0.1 3.8 4 1 0 4 4 3 0 ABC transporter SKI PF01202.22 EGC33391.1 - 0.16 12.1 0.0 0.16 12.1 0.0 2.7 3 1 0 3 3 1 0 Shikimate kinase AAA_11 PF13086.6 EGC33391.1 - 0.29 10.9 0.1 0.29 10.9 0.1 3.7 3 1 0 3 3 2 0 AAA domain PhoPQ_related PF10142.9 EGC33392.1 - 1e-122 409.3 7.2 1.2e-122 409.1 7.2 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF2505 PF10698.9 EGC33393.1 - 4.1e-05 23.8 0.0 5.6e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2505) PRELI PF04707.14 EGC33393.1 - 0.0036 17.1 0.4 0.0051 16.6 0.4 1.2 1 0 0 1 1 1 1 PRELI-like family Y1_Tnp PF01797.16 EGC33393.1 - 0.019 15.1 1.0 0.036 14.2 0.2 1.9 1 1 1 2 2 2 0 Transposase IS200 like RNase_T PF00929.24 EGC33394.1 - 3.8e-07 30.8 0.1 9.6e-07 29.5 0.1 1.7 1 0 0 1 1 1 1 Exonuclease 7TM_GPCR_Srb PF02175.16 EGC33394.1 - 0.0018 18.1 1.0 0.0036 17.1 1.0 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb DUF5051 PF16473.5 EGC33394.1 - 0.012 15.6 0.1 0.03 14.3 0.1 1.7 1 0 0 1 1 1 0 3' exoribonuclease, RNase T-like Vta1 PF04652.16 EGC33394.1 - 0.33 10.9 3.3 0.83 9.6 0.0 3.1 4 1 0 4 4 4 0 Vta1 like SLATT_4 PF18186.1 EGC33395.1 - 0.064 12.9 1.9 0.07 12.8 1.9 1.1 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 4 Secretin_N_2 PF07655.13 EGC33397.1 - 0.053 14.1 6.7 0.049 14.2 6.7 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Corazonin PF17308.2 EGC33397.1 - 5.5 7.4 11.2 5.8 7.3 11.2 1.1 1 0 0 1 1 1 0 Pro-corazonin EGF_Tenascin PF18720.1 EGC33399.1 - 1.8 8.7 6.1 4.4 7.5 6.1 1.7 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EGC33399.1 - 2.1 8.8 14.9 0.06 13.7 8.6 1.7 2 0 0 2 2 2 0 EGF-like domain TIG PF01833.24 EGC33401.1 - 1.1e-14 54.3 38.2 1.9e-05 24.6 4.1 7.1 7 0 0 7 7 7 5 IPT/TIG domain PH_15 PF17339.2 EGC33401.1 - 0.14 12.0 0.3 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 PH domain GATA PF00320.27 EGC33403.1 - 2.1e-07 30.4 4.2 3.5e-07 29.7 4.2 1.3 1 0 0 1 1 1 1 GATA zinc finger Homeodomain PF00046.29 EGC33404.1 - 7.9e-14 51.2 1.9 4e-07 29.8 0.1 2.8 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC33404.1 - 2.8e-07 30.3 0.1 0.0012 18.7 0.0 2.8 2 0 0 2 2 2 2 Homeobox KN domain GATA PF00320.27 EGC33405.1 - 1.1e-06 28.1 9.8 2.1e-06 27.2 9.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Pox_RNA_Pol_19 PF05320.12 EGC33406.1 - 0.27 11.2 4.0 0.2 11.6 3.0 1.4 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PPK2 PF03976.14 EGC33407.1 - 0.033 13.7 0.3 0.51 9.8 0.0 2.5 2 1 1 3 3 3 0 Polyphosphate kinase 2 (PPK2) RNase_T PF00929.24 EGC33407.1 - 0.038 14.5 0.1 0.074 13.6 0.1 1.5 1 0 0 1 1 1 0 Exonuclease HMG_box PF00505.19 EGC33409.1 - 3.7e-18 65.7 2.6 4.4e-18 65.5 2.6 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC33409.1 - 2.6e-13 50.3 3.0 3.3e-13 50.0 3.0 1.1 1 0 0 1 1 1 1 HMG-box domain TIG PF01833.24 EGC33410.1 - 8.1e-10 38.6 53.5 1.2e-05 25.3 3.5 7.7 7 1 1 8 8 8 5 IPT/TIG domain CARDB PF07705.11 EGC33410.1 - 0.0034 17.6 1.4 0.0034 17.6 1.4 3.5 3 1 0 3 3 3 1 CARDB Tudor_2 PF18104.1 EGC33410.1 - 0.16 11.7 1.0 9.3 6.0 0.1 2.8 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TBP-binding PF09247.11 EGC33410.1 - 0.76 10.1 3.5 0.41 10.9 0.6 2.0 2 0 0 2 2 2 0 TATA box-binding protein binding TTSSLRR PF12468.8 EGC33410.1 - 5.2 7.4 5.9 19 5.6 0.1 3.1 2 0 0 2 2 2 0 Type III secretion system leucine rich repeat protein FNIP PF05725.12 EGC33411.1 - 7.3e-31 106.1 43.1 1.8e-12 47.2 6.3 4.8 4 1 1 5 5 5 5 FNIP Repeat KR PF08659.10 EGC33412.1 - 2.6e-07 30.7 0.0 4.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PP-binding PF00550.25 EGC33412.1 - 1.3e-05 25.5 0.0 2.5e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site WGR PF05406.15 EGC33412.1 - 0.14 12.2 0.4 2.2 8.4 0.0 2.4 2 0 0 2 2 2 0 WGR domain ketoacyl-synt PF00109.26 EGC33413.1 - 8.3e-42 143.5 0.0 1.3e-41 142.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC33413.1 - 6.1e-21 74.6 0.0 3.8e-20 72.1 0.0 2.3 2 1 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.12 EGC33413.1 - 1.5e-19 70.6 0.0 8.1e-19 68.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Acyl_transf_1 PF00698.21 EGC33413.1 - 3.4e-19 69.5 0.0 5.1e-11 42.6 0.0 3.3 3 0 0 3 3 3 3 Acyl transferase domain PS-DH PF14765.6 EGC33413.1 - 3.6e-19 69.1 0.0 5.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC33413.1 - 2.4e-16 60.2 0.1 4.9e-15 56.0 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_N PF08240.12 EGC33413.1 - 7.1e-08 32.3 0.0 1.7e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 EGC33413.1 - 8.1e-08 32.2 0.2 4.9e-07 29.6 0.1 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC33413.1 - 7.4e-07 29.1 0.0 1.8e-06 27.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC33413.1 - 6.3e-06 26.8 0.0 1.9e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC33413.1 - 0.0046 16.3 0.0 0.014 14.7 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.6 EGC33413.1 - 0.0076 17.3 0.0 0.021 15.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EGC33413.1 - 0.0077 15.6 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 EGC33413.1 - 0.025 14.2 0.0 0.087 12.4 0.0 1.9 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ADH_zinc_N PF00107.26 EGC33413.1 - 0.046 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Zinc-binding dehydrogenase TIG PF01833.24 EGC33414.1 - 1.1e-14 54.3 41.5 8.4e-06 25.8 1.2 7.5 7 0 0 7 7 7 4 IPT/TIG domain Tudor_2 PF18104.1 EGC33414.1 - 0.041 13.6 0.8 13 5.6 0.1 3.0 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TBP-binding PF09247.11 EGC33414.1 - 0.42 10.9 3.5 0.2 11.9 0.4 2.0 2 0 0 2 2 2 0 TATA box-binding protein binding CARDB PF07705.11 EGC33414.1 - 6.4 7.1 9.2 0.22 11.8 0.8 3.1 4 0 0 4 4 4 0 CARDB Ribosomal_S15 PF00312.22 EGC33415.1 - 2.7e-22 78.7 2.8 2.7e-22 78.7 2.8 2.4 2 0 0 2 2 2 1 Ribosomal protein S15 Pcc1 PF09341.10 EGC33416.1 - 1.1e-12 47.9 0.1 1.2e-12 47.7 0.1 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 FHA PF00498.26 EGC33417.1 - 4.4e-17 62.2 0.0 1.1e-16 61.0 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC33417.1 - 2.8e-06 27.5 0.0 6.5e-06 26.4 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Bul1_C PF04426.12 EGC33417.1 - 1.4 8.3 12.3 0.56 9.6 3.0 2.1 2 0 0 2 2 2 0 Bul1 C terminus MCM_bind PF09739.9 EGC33417.1 - 3.6 5.9 16.4 0.67 8.3 5.0 2.1 2 0 0 2 2 2 0 Mini-chromosome maintenance replisome factor DUF3808 PF10300.9 EGC33419.1 - 1.6e-42 145.9 4.2 1.6e-42 145.9 4.2 1.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3808) TPR_2 PF07719.17 EGC33419.1 - 1.5e-06 27.9 9.4 0.2 11.8 0.3 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_6 PF13174.6 EGC33419.1 - 0.00029 21.3 2.4 0.28 11.9 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC33419.1 - 0.0042 17.2 13.1 0.14 12.5 0.7 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat PPR PF01535.20 EGC33419.1 - 0.0056 16.9 1.3 0.29 11.5 0.0 3.8 4 0 0 4 4 4 1 PPR repeat TPR_12 PF13424.6 EGC33419.1 - 0.011 16.0 4.9 6.5 7.1 0.0 4.5 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC33419.1 - 0.19 11.6 17.0 2.8 7.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC33419.1 - 4.8 7.5 13.4 0.95 9.7 3.3 4.2 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 LRR_6 PF13516.6 EGC33420.1 - 4.7e-10 38.7 26.1 0.014 15.4 0.2 8.4 9 0 0 9 9 9 4 Leucine Rich repeat Carm_PH PF17888.1 EGC33420.1 - 2.4e-08 34.2 0.6 2.4e-08 34.2 0.6 2.2 2 0 0 2 2 2 1 Carmil pleckstrin homology domain Myosin_TH1 PF06017.13 EGC33420.1 - 0.00011 22.0 2.2 0.00032 20.4 2.2 1.7 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding bPH_3 PF14470.6 EGC33420.1 - 0.02 15.3 1.9 0.065 13.6 1.9 1.9 1 0 0 1 1 1 0 Bacterial PH domain LRR_4 PF12799.7 EGC33420.1 - 0.025 15.0 24.1 1.2 9.7 0.1 6.5 5 1 2 7 7 7 0 Leucine Rich repeats (2 copies) PH_3 PF14593.6 EGC33420.1 - 0.085 13.0 2.1 0.26 11.4 2.1 1.8 1 0 0 1 1 1 0 PH domain RSN1_7TM PF02714.15 EGC33421.1 - 0.00047 19.6 31.2 0.00047 19.6 31.2 2.2 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate ILEI PF15711.5 EGC33422.1 - 5e-12 46.1 0.5 8.9e-12 45.3 0.2 1.6 1 1 1 2 2 2 1 Interleukin-like EMT inducer PTPA PF03095.15 EGC33423.1 - 3.9e-115 384.5 0.0 4.9e-115 384.1 0.0 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein KOG2701 PF09762.9 EGC33424.1 - 2.7e-60 203.6 0.0 2.7e-60 203.6 0.0 4.2 3 1 0 4 4 4 1 Coiled-coil domain-containing protein (DUF2037) HV_small_capsid PF17086.5 EGC33424.1 - 0.001 19.3 0.2 0.0069 16.6 0.1 2.4 2 0 0 2 2 2 1 Small capsid protein of Herpesviridae RNase_HII PF01351.18 EGC33424.1 - 2.7 7.8 8.7 0.32 10.8 3.5 2.2 2 0 0 2 2 2 0 Ribonuclease HII TRAPPC-Trs85 PF12739.7 EGC33425.1 - 8.7e-56 189.6 6.7 1.2e-50 172.7 0.1 4.0 3 1 1 4 4 4 2 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF974 PF06159.13 EGC33425.1 - 0.0039 17.0 8.1 0.2 11.4 0.0 3.4 2 1 1 3 3 3 2 Protein of unknown function (DUF974) Transglut_C PF00927.22 EGC33425.1 - 0.011 15.8 0.3 10 6.4 0.0 4.0 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain Gti1_Pac2 PF09729.9 EGC33425.1 - 0.39 10.8 5.8 0.11 12.6 1.4 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family Peptidase_C92 PF05708.12 EGC33426.1 - 3.1e-06 27.4 0.0 3.5e-05 24.0 0.0 2.4 1 1 0 1 1 1 1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family zf-TRAF PF02176.18 EGC33427.1 - 0.00015 22.4 21.0 0.00034 21.3 4.6 4.9 2 1 4 6 6 6 4 TRAF-type zinc finger DivIVA PF05103.13 EGC33427.1 - 0.029 14.5 5.3 0.063 13.4 5.3 1.5 1 0 0 1 1 1 0 DivIVA protein CorA PF01544.18 EGC33427.1 - 0.045 13.1 0.4 0.066 12.5 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein bZIP_2 PF07716.15 EGC33427.1 - 0.054 13.6 6.2 0.15 12.2 6.2 1.8 1 0 0 1 1 1 0 Basic region leucine zipper DUF5320 PF17253.2 EGC33427.1 - 0.095 13.8 0.8 0.17 13.0 0.8 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) DivIC PF04977.15 EGC33427.1 - 0.12 12.2 5.0 0.33 10.8 5.0 1.7 1 0 0 1 1 1 0 Septum formation initiator Cep57_CLD_2 PF14197.6 EGC33427.1 - 0.16 12.1 6.4 0.047 13.8 3.3 1.7 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 ZapB PF06005.12 EGC33427.1 - 2.8 8.5 11.8 1.2 9.6 8.5 1.9 2 0 0 2 2 2 0 Cell division protein ZapB Acetyltransf_1 PF00583.25 EGC33429.1 - 0.027 14.7 0.0 0.045 14.0 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC33429.1 - 0.11 13.0 0.0 0.19 12.2 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-L PF02585.17 EGC33430.1 - 3.6e-26 92.3 0.0 5.3e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase CLN3 PF02487.17 EGC33430.1 - 0.12 11.4 1.9 0.16 11.0 1.9 1.2 1 0 0 1 1 1 0 CLN3 protein zf-RING_2 PF13639.6 EGC33431.1 - 1.8e-13 50.6 10.0 2.4e-13 50.2 10.0 1.2 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC33431.1 - 8.7e-11 41.4 10.6 1.4e-10 40.7 10.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC33431.1 - 5.3e-08 33.0 10.7 1.3e-07 31.8 10.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC33431.1 - 8.5e-07 28.7 10.0 1.2e-06 28.2 10.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33431.1 - 7.5e-06 25.7 10.1 1.2e-05 25.1 10.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC33431.1 - 5e-05 23.2 8.8 7.4e-05 22.6 8.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC33431.1 - 0.001 18.9 8.3 0.0014 18.4 8.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGC33431.1 - 0.0016 18.0 7.6 0.0022 17.6 7.6 1.2 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGC33431.1 - 0.0041 17.1 5.9 0.007 16.4 5.8 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.6 EGC33431.1 - 0.0041 17.2 3.5 0.0049 17.0 3.5 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain zf-RING_UBOX PF13445.6 EGC33431.1 - 0.0078 16.2 9.6 0.012 15.6 9.6 1.3 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC33431.1 - 0.03 14.2 6.6 0.057 13.3 6.7 1.5 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 ParB PF08775.10 EGC33431.1 - 0.041 14.4 0.1 0.05 14.1 0.1 1.1 1 0 0 1 1 1 0 ParB family RINGv PF12906.7 EGC33431.1 - 0.21 11.7 7.9 0.52 10.5 7.9 1.6 1 1 0 1 1 1 0 RING-variant domain FANCL_C PF11793.8 EGC33431.1 - 0.28 11.4 7.6 0.6 10.3 7.6 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Voltage_CLC PF00654.20 EGC33432.1 - 3.4e-77 260.1 22.1 5.4e-77 259.4 22.1 1.3 1 0 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.28 EGC33432.1 - 8.2e-06 26.2 0.1 0.003 18.0 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF2207 PF09972.9 EGC33433.1 - 0.0044 15.9 3.7 0.0061 15.4 3.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) FA_desaturase PF00487.24 EGC33433.1 - 0.097 12.5 1.1 0.12 12.2 1.1 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF2070 PF09843.9 EGC33433.1 - 0.22 9.8 2.8 0.27 9.5 2.8 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PLAC8 PF04749.17 EGC33434.1 - 6.9e-06 27.0 16.7 2.7e-05 25.1 16.7 2.5 1 1 0 1 1 1 1 PLAC8 family DUF4007 PF13182.6 EGC33434.1 - 0.0038 16.4 0.0 0.0052 15.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF4007) NAD_binding_4 PF07993.12 EGC33435.1 - 1.9e-43 148.5 0.0 3.4e-43 147.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGC33435.1 - 4.4e-06 26.3 0.0 8.3e-06 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC33435.1 - 1.1e-05 24.5 0.2 2.6e-05 23.4 0.2 1.6 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC33435.1 - 0.00042 19.8 0.1 0.00074 19.0 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC33435.1 - 0.00059 19.1 0.3 0.0011 18.1 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MacB_PCD PF12704.7 EGC33435.1 - 0.0065 16.8 0.8 0.047 14.0 0.1 2.6 3 0 0 3 3 3 1 MacB-like periplasmic core domain EGF_2 PF07974.13 EGC33435.1 - 3.4 8.1 9.5 8.4 6.9 9.5 1.7 1 0 0 1 1 1 0 EGF-like domain ATP12 PF07542.11 EGC33436.1 - 2.3e-23 82.7 0.0 3.8e-23 82.0 0.0 1.4 1 0 0 1 1 1 1 ATP12 chaperone protein ox_reductase_C PF08635.10 EGC33436.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal domain Rad50_zn_hook PF04423.14 EGC33436.1 - 0.93 9.4 4.1 14 5.6 0.4 2.9 3 0 0 3 3 3 0 Rad50 zinc hook motif MTS PF05175.14 EGC33437.1 - 6.7e-13 48.5 0.0 4.5e-12 45.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGC33437.1 - 7.3e-10 38.7 0.0 1.1e-09 38.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.6 EGC33437.1 - 1e-07 31.9 0.0 1.7e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC33437.1 - 6.7e-07 29.9 0.0 1.1e-06 29.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC33437.1 - 7.2e-07 29.1 0.0 1.1e-06 28.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGC33437.1 - 2.5e-06 27.4 0.0 3.8e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein TehB PF03848.14 EGC33437.1 - 1.4e-05 24.6 0.0 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_11 PF08241.12 EGC33437.1 - 4.2e-05 24.1 0.0 7.5e-05 23.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC33437.1 - 0.00091 19.9 0.0 0.0016 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.9 EGC33437.1 - 0.0014 18.4 0.0 0.0024 17.6 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase RrnaAD PF00398.20 EGC33437.1 - 0.0045 16.1 0.0 0.0068 15.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase PCMT PF01135.19 EGC33437.1 - 0.017 14.9 0.0 0.025 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MethyltransfD12 PF02086.15 EGC33437.1 - 0.023 14.4 0.1 0.037 13.7 0.1 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.16 EGC33437.1 - 0.053 12.7 0.0 0.076 12.2 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase Methyltr_RsmB-F PF01189.17 EGC33437.1 - 0.17 11.5 0.0 0.4 10.3 0.0 1.6 1 1 0 1 1 1 0 16S rRNA methyltransferase RsmB/F Palm_thioest PF02089.15 EGC33438.1 - 9.4e-78 261.4 0.1 1.1e-77 261.1 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Lipase_2 PF01674.18 EGC33438.1 - 0.00072 19.1 0.0 0.014 14.9 0.0 2.2 1 1 0 1 1 1 1 Lipase (class 2) Abhydrolase_1 PF00561.20 EGC33438.1 - 0.00083 19.1 0.0 0.051 13.2 0.0 2.6 2 1 1 3 3 3 1 alpha/beta hydrolase fold DUF676 PF05057.14 EGC33438.1 - 0.059 12.9 0.0 0.14 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) 7tm_2 PF00002.24 EGC33439.1 - 1.7e-25 89.8 15.3 2.1e-25 89.5 15.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGC33439.1 - 1.1e-20 74.0 15.7 1.2e-20 73.8 15.7 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 EGC33439.1 - 9.8e-11 41.3 18.0 3.6e-07 29.5 2.4 2.2 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Ocular_alb PF02101.15 EGC33439.1 - 9.6e-09 34.6 3.9 3.6e-08 32.8 3.3 2.0 2 0 0 2 2 2 1 Ocular albinism type 1 protein FR47 PF08445.10 EGC33440.1 - 3.6e-07 30.1 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EGC33440.1 - 0.00067 19.3 0.2 0.0021 17.7 0.0 1.9 2 1 0 2 2 2 1 GNAT acetyltransferase Gly_acyl_tr_C PF08444.10 EGC33440.1 - 0.0056 16.9 0.2 0.049 13.9 0.0 2.5 3 1 0 3 3 3 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_3 PF13302.7 EGC33440.1 - 0.03 15.0 0.0 0.067 13.9 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC33440.1 - 0.07 13.4 0.0 0.16 12.2 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC33440.1 - 0.099 13.1 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain CemA PF03040.14 EGC33440.1 - 0.12 12.2 3.3 0.094 12.6 1.6 1.6 1 1 1 2 2 2 0 CemA family Put_DNA-bind_N PF06971.13 EGC33440.1 - 0.17 11.9 0.2 0.35 10.9 0.2 1.5 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus Rieske_3 PF18465.1 EGC33440.1 - 0.17 12.1 0.1 0.43 10.9 0.1 1.6 1 0 0 1 1 1 0 Rieske 3Fe-4S DPBB_1 PF03330.18 EGC33441.1 - 1.4e-09 38.1 0.2 4.9e-09 36.3 0.2 2.0 1 1 0 1 1 1 1 Lytic transglycolase LysM PF01476.20 EGC33441.1 - 1.7e-05 24.8 0.2 0.11 12.6 0.1 2.5 2 0 0 2 2 2 2 LysM domain RabGAP-TBC PF00566.18 EGC33444.1 - 5.9e-39 134.0 7.7 7.1e-39 133.7 7.7 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain BAR PF03114.18 EGC33445.1 - 2.2e-17 63.5 10.4 5e-17 62.3 10.4 1.5 1 1 0 1 1 1 1 BAR domain SH3_1 PF00018.28 EGC33445.1 - 8.8e-10 38.0 0.0 1.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC33445.1 - 1.3e-09 37.8 0.0 2.1e-09 37.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC33445.1 - 4.2e-06 26.3 0.0 7.8e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain DUF4061 PF13270.6 EGC33445.1 - 0.025 14.9 1.7 8 6.9 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4061) Arfaptin PF06456.13 EGC33445.1 - 0.14 11.7 8.5 0.3 10.6 0.5 2.2 2 0 0 2 2 2 0 Arfaptin-like domain Fib_alpha PF08702.10 EGC33445.1 - 4.7 7.4 8.1 1.4 9.1 0.8 2.8 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family CBM49 PF09478.10 EGC33446.1 - 2.4e-15 56.6 0.2 3.3e-15 56.1 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TRAP_alpha PF03896.16 EGC33447.1 - 9.1e-34 116.9 1.6 1.1e-33 116.7 1.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit PRK PF00485.18 EGC33448.1 - 3.9e-25 88.8 1.8 5.9e-24 84.9 1.8 2.2 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 EGC33448.1 - 2.3e-09 37.4 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 CYTH domain AAA_33 PF13671.6 EGC33448.1 - 0.0011 19.2 0.0 0.002 18.3 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC33448.1 - 0.0013 19.3 0.0 0.003 18.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGC33448.1 - 0.0014 17.8 0.2 0.0032 16.7 0.2 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_24 PF13479.6 EGC33448.1 - 0.0052 16.5 0.0 0.017 14.9 0.0 1.8 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGC33448.1 - 0.0054 16.7 0.0 0.016 15.1 0.0 1.8 2 0 0 2 2 2 1 NACHT domain SURNod19 PF07712.12 EGC33448.1 - 0.0082 14.9 0.0 0.012 14.4 0.0 1.2 1 0 0 1 1 1 1 Stress up-regulated Nod 19 ATPase_2 PF01637.18 EGC33448.1 - 0.011 15.6 0.3 0.032 14.2 0.0 2.0 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGC33448.1 - 0.012 16.1 0.0 0.018 15.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain RsgA_GTPase PF03193.16 EGC33448.1 - 0.015 15.2 0.4 0.034 14.1 0.1 1.7 2 0 0 2 2 2 0 RsgA GTPase NTPase_1 PF03266.15 EGC33448.1 - 0.016 15.1 0.1 0.36 10.7 0.1 2.5 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.27 EGC33448.1 - 0.021 15.3 0.0 0.052 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGC33448.1 - 0.022 14.1 0.1 0.062 12.6 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.21 EGC33448.1 - 0.044 13.2 0.0 0.086 12.2 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.22 EGC33448.1 - 0.045 14.1 0.1 1.4 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase MobB PF03205.14 EGC33448.1 - 0.063 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EGC33448.1 - 0.1 13.0 0.1 0.46 10.9 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC33448.1 - 0.16 11.9 0.0 0.48 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAR2 PF05282.11 EGC33449.1 - 7.9e-104 347.8 5.3 7.9e-104 347.8 5.3 1.7 2 0 0 2 2 2 1 AAR2 protein NINJA_B PF16136.5 EGC33449.1 - 0.011 16.1 0.5 0.011 16.1 0.5 2.1 2 0 0 2 2 2 0 Putative nuclear localisation signal VPS13_C PF16909.5 EGC33451.1 - 6.1e-56 189.0 10.5 2.2e-52 177.4 0.8 3.9 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGC33451.1 - 4e-43 147.7 8.3 4e-43 147.7 8.3 6.7 5 1 0 5 5 5 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13 PF16908.5 EGC33451.1 - 5.9e-36 124.4 2.1 5.9e-36 124.4 2.1 5.0 5 0 0 5 5 5 1 Vacuolar sorting-associated protein 13, N-terminal Chorein_N PF12624.7 EGC33451.1 - 1e-30 106.2 0.1 1e-30 106.2 0.1 5.8 2 1 1 3 3 3 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGC33451.1 - 8e-07 29.3 0.0 3.6e-06 27.2 0.0 2.1 1 0 0 1 1 1 1 Autophagy-related protein C terminal domain Mit_KHE1 PF10173.9 EGC33452.1 - 0.24 11.5 5.7 0.44 10.6 1.4 2.4 2 0 0 2 2 2 0 Mitochondrial K+-H+ exchange-related Vps54 PF07928.12 EGC33452.1 - 0.26 11.7 0.1 0.26 11.7 0.1 3.1 3 1 1 4 4 4 0 Vps54-like protein M60-like_N PF17291.2 EGC33453.1 - 0.0095 15.8 0.0 0.016 15.0 0.0 1.3 1 0 0 1 1 1 1 N-terminal domain of M60-like peptidases RL PF17797.1 EGC33453.1 - 0.085 12.8 0.1 0.26 11.3 0.1 1.8 1 0 0 1 1 1 0 RL domain PIG-X PF08320.12 EGC33454.1 - 4.9e-38 131.2 0.3 1.1e-37 130.0 0.3 1.6 1 0 0 1 1 1 1 PIG-X / PBN1 DNA_meth_N PF18284.1 EGC33454.1 - 0.055 13.4 0.2 0.29 11.0 0.2 2.1 2 0 0 2 2 2 0 DNA methylase N-terminal domain Glyco_hydro_9 PF00759.19 EGC33455.1 - 4.3e-124 415.1 13.2 5e-124 414.9 13.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 GST_N_2 PF13409.6 EGC33457.1 - 3.8e-22 78.4 0.0 1.4e-21 76.6 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC33457.1 - 5.3e-13 48.8 0.0 9.1e-13 48.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC33457.1 - 4.8e-10 39.5 0.0 7.7e-10 38.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC33457.1 - 1.1e-06 28.9 0.0 1.4e-05 25.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC33457.1 - 3.4e-06 27.2 0.0 9.4e-06 25.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC33457.1 - 7.4e-05 22.5 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EGC33457.1 - 0.087 12.7 0.0 0.93 9.3 0.0 2.5 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain Lectin_legB PF00139.19 EGC33458.1 - 1.7e-15 57.2 3.4 1.7e-15 57.2 3.4 1.8 1 1 0 2 2 2 1 Legume lectin domain Bact_lectin PF18483.1 EGC33458.1 - 3.6e-11 43.5 2.6 3.6e-11 43.5 2.6 2.2 1 1 1 2 2 2 1 Bacterial lectin Lectin_leg-like PF03388.13 EGC33458.1 - 0.0006 19.2 3.3 0.19 11.1 0.1 2.5 2 1 0 2 2 2 2 Legume-like lectin family Abhydrolase_3 PF07859.13 EGC33459.1 - 2.2e-13 50.6 0.0 3.2e-13 50.0 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold COesterase PF00135.28 EGC33459.1 - 8.7e-06 24.9 0.3 4e-05 22.7 0.3 1.9 1 1 0 1 1 1 1 Carboxylesterase family Peptidase_S9 PF00326.21 EGC33459.1 - 9.6e-05 22.0 0.0 0.016 14.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC33459.1 - 0.0023 17.2 0.1 0.14 11.4 0.1 2.3 1 1 0 1 1 1 1 Serine aminopeptidase, S33 LIDHydrolase PF10230.9 EGC33459.1 - 0.003 17.1 1.8 0.0099 15.5 0.2 2.2 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Abhydrolase_5 PF12695.7 EGC33459.1 - 0.012 15.3 0.1 0.059 13.1 0.0 2.2 2 1 1 3 3 3 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGC33459.1 - 0.013 15.3 0.4 0.031 14.0 0.4 1.7 1 1 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.14 EGC33459.1 - 0.036 13.6 0.1 0.054 13.0 0.1 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EGC33459.1 - 0.039 13.6 0.1 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase2 PF12740.7 EGC33459.1 - 0.14 11.0 0.0 0.34 9.8 0.0 1.6 2 0 0 2 2 2 0 Chlorophyllase enzyme Lipase_3 PF01764.25 EGC33459.1 - 0.15 11.9 0.1 0.36 10.7 0.1 1.8 1 1 0 1 1 1 0 Lipase (class 3) GTP_EFTU PF00009.27 EGC33460.1 - 1e-41 142.6 0.4 1.7e-41 141.9 0.0 1.6 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain EFTUD2 PF16004.5 EGC33460.1 - 1.1e-33 116.4 15.4 2.4e-33 115.3 15.4 1.6 1 0 0 1 1 1 1 116 kDa U5 small nuclear ribonucleoprotein component N-terminus EFG_IV PF03764.18 EGC33460.1 - 2.5e-21 75.7 0.0 8.3e-21 74.0 0.0 1.9 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.24 EGC33460.1 - 1.7e-20 72.8 0.0 2.3e-19 69.2 0.0 2.4 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC33460.1 - 4.1e-09 36.7 0.0 9.2e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.6 EGC33460.1 - 2.7e-07 30.6 0.0 6.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Septin PF00735.18 EGC33460.1 - 0.0025 17.2 0.0 0.0059 15.9 0.0 1.6 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGC33460.1 - 0.0041 17.2 0.0 0.012 15.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase V_ATPase_I PF01496.19 EGC33460.1 - 0.065 11.2 3.5 0.092 10.7 3.5 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Roc PF08477.13 EGC33460.1 - 0.11 12.7 0.0 0.57 10.4 0.0 2.2 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PH PF00169.29 EGC33462.1 - 5.1e-15 55.9 0.1 1.3e-14 54.5 0.1 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC33462.1 - 0.014 15.8 1.5 0.014 15.8 1.5 3.3 2 2 1 3 3 3 0 Pleckstrin homology domain PH_9 PF15410.6 EGC33462.1 - 0.023 15.1 1.9 0.067 13.6 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain Macoilin PF09726.9 EGC33462.1 - 0.037 12.6 11.4 0.041 12.4 11.4 1.0 1 0 0 1 1 1 0 Macoilin family Opi1 PF08618.10 EGC33462.1 - 0.092 12.0 4.4 0.12 11.6 4.4 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 PNISR PF15996.5 EGC33462.1 - 0.15 12.3 6.5 0.19 12.0 6.5 1.2 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR LMBR1 PF04791.16 EGC33462.1 - 5 5.9 5.4 5.6 5.7 5.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DSPc PF00782.20 EGC33463.1 - 2e-25 89.1 5.3 2e-25 89.1 5.3 3.6 2 2 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGC33463.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Neur_chan_memb PF02932.16 EGC33463.1 - 0.79 9.7 4.1 0.82 9.7 2.9 1.6 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Gti1_Pac2 PF09729.9 EGC33463.1 - 3.2 7.8 13.4 8.9 6.4 11.7 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family PA26 PF04636.13 EGC33463.1 - 9.1 5.1 11.7 1.8 7.4 8.3 1.5 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) G-alpha PF00503.20 EGC33464.1 - 8.6e-103 344.2 7.1 1.1e-102 343.9 7.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC33464.1 - 7.2e-16 58.1 1.1 3.5e-11 42.9 0.3 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC33464.1 - 1.5e-05 25.2 0.9 0.029 14.6 0.1 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGC33464.1 - 0.00011 21.6 1.5 0.033 13.6 0.2 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region CPT PF07931.12 EGC33464.1 - 0.00042 20.2 0.0 0.002 18.0 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Ras PF00071.22 EGC33464.1 - 0.0027 17.3 1.7 0.88 9.2 0.4 2.5 2 1 0 2 2 2 2 Ras family DUF2855 PF11017.8 EGC33464.1 - 0.2 11.4 0.0 0.57 9.9 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2855) zf-RING_2 PF13639.6 EGC33467.1 - 1.6e-08 34.8 9.9 3.1e-08 33.8 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33467.1 - 1.4e-07 31.2 8.8 2.8e-07 30.3 8.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC33467.1 - 2.7e-07 30.3 7.9 4.8e-07 29.5 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33467.1 - 3e-07 30.2 11.4 8.4e-07 28.8 11.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33467.1 - 0.00012 22.0 5.2 0.00041 20.3 5.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC33467.1 - 0.0011 19.2 9.2 0.0044 17.3 9.2 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC33467.1 - 0.007 16.5 9.4 0.015 15.4 9.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC33467.1 - 0.0092 15.9 9.7 0.019 14.9 9.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC33467.1 - 0.021 14.7 7.7 0.052 13.4 7.7 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4834 PF16118.5 EGC33467.1 - 0.035 15.1 4.0 0.035 15.1 4.0 6.1 1 1 1 2 2 1 0 Domain of unknown function (DUF4834) zf-RING_4 PF14570.6 EGC33467.1 - 0.075 12.8 8.1 0.15 11.9 8.1 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC33467.1 - 0.37 10.9 3.7 0.85 9.8 3.7 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 EGC33467.1 - 0.85 9.7 5.7 2.3 8.3 5.7 1.7 1 0 0 1 1 1 0 Double zinc ribbon DUF1272 PF06906.11 EGC33467.1 - 0.96 9.6 6.5 1.8 8.7 6.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 EGC33467.1 - 3 7.6 6.9 6.5 6.6 6.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger XRN_N PF03159.18 EGC33468.1 - 2.4e-72 243.3 0.0 5e-72 242.2 0.0 1.6 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PITH PF06201.13 EGC33468.1 - 1.1e-22 80.9 5.9 3.1e-22 79.4 5.9 1.9 1 0 0 1 1 1 1 PITH domain RRM_1 PF00076.22 EGC33468.1 - 8.2e-17 60.8 2.0 1.8e-08 34.1 0.1 2.8 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) XRN_M PF17846.1 EGC33468.1 - 5.9e-11 42.0 0.0 1.8e-10 40.4 0.0 1.9 1 0 0 1 1 1 1 Xrn1 helical domain zf-CCHC_3 PF13917.6 EGC33468.1 - 0.00013 21.9 0.6 0.0003 20.7 0.6 1.6 1 0 0 1 1 1 1 Zinc knuckle RL PF17797.1 EGC33468.1 - 0.15 12.0 0.7 1.2 9.1 0.2 2.8 2 0 0 2 2 2 0 RL domain RGS12_usC PF16612.5 EGC33468.1 - 0.88 10.0 14.8 1.9 8.9 2.3 2.7 2 0 0 2 2 2 0 C-terminal unstructured region of RGS12 APG5 PF04106.12 EGC33469.1 - 5.2e-54 183.3 0.8 7e-54 182.8 0.8 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 HhH-GPD PF00730.25 EGC33470.1 - 0.0035 17.8 0.0 0.0037 17.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein ketoacyl-synt PF00109.26 EGC33471.1 - 5.6e-60 203.0 0.0 8.4e-60 202.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC33471.1 - 6e-46 156.7 0.0 1.2e-45 155.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC33471.1 - 3.8e-42 144.9 0.0 5.9e-42 144.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC33471.1 - 2.3e-29 101.8 0.0 4.7e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC33471.1 - 7e-22 78.2 0.0 2.8e-21 76.2 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EGC33471.1 - 1e-20 74.3 0.0 6.4e-20 71.8 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 EGC33471.1 - 1.7e-17 63.6 0.0 2.6e-17 63.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC33471.1 - 5e-13 49.5 0.2 2.1e-12 47.4 0.1 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC33471.1 - 1.1e-09 39.4 0.0 5.5e-09 37.2 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGC33471.1 - 7.9e-08 32.3 0.0 2.6e-07 30.6 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC33471.1 - 1.9e-06 28.4 0.0 5.8e-06 26.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC33471.1 - 2.9e-05 23.9 0.0 0.00034 20.4 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EGC33471.1 - 7.8e-05 22.2 0.0 0.00018 21.0 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGC33471.1 - 0.00078 19.8 0.5 0.0016 18.7 0.5 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site GDP_Man_Dehyd PF16363.5 EGC33471.1 - 0.0063 16.0 0.4 1.1 8.6 0.0 2.7 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC33471.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.8 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family EGF_2 PF07974.13 EGC33472.1 - 0.00031 21.0 19.3 0.00088 19.6 9.1 2.7 2 0 0 2 2 2 2 EGF-like domain Hen1_Lam_C PF18441.1 EGC33472.1 - 0.052 13.4 0.4 0.6 9.9 0.2 2.6 2 0 0 2 2 2 0 Hen1 La-motif C-terminal domain EGF_Tenascin PF18720.1 EGC33472.1 - 0.086 12.9 8.1 0.23 11.6 5.6 2.5 2 0 0 2 2 2 0 Tenascin EGF domain EGF_alliinase PF04863.13 EGC33472.1 - 1.4 9.4 4.6 5 7.6 4.6 1.9 1 0 0 1 1 1 0 Alliinase EGF-like domain AMP-binding PF00501.28 EGC33474.1 - 9.3e-67 225.5 0.0 1.1e-66 225.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC33474.1 - 1.7e-10 40.7 4.4 5.7e-10 39.0 4.4 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus Actin PF00022.19 EGC33475.1 - 3e-152 507.0 0.0 9.6e-152 505.3 0.0 1.6 1 1 0 1 1 1 1 Actin adh_short PF00106.25 EGC33476.1 - 5.1e-49 166.4 0.0 7.9e-49 165.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33476.1 - 9.1e-29 100.7 0.0 1.2e-28 100.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33476.1 - 2.1e-10 40.8 1.0 2e-09 37.6 1.0 2.1 1 1 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC33476.1 - 1.3e-05 24.8 0.2 0.00015 21.3 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGC33476.1 - 0.00018 21.5 0.0 0.0075 16.2 0.0 2.3 2 0 0 2 2 2 1 NAD(P)H-binding Pyr_redox_2 PF07992.14 EGC33476.1 - 0.00039 19.8 0.0 0.00058 19.2 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Polysacc_synt_2 PF02719.15 EGC33476.1 - 0.00067 18.9 0.1 0.0011 18.2 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein 3HCDH_N PF02737.18 EGC33476.1 - 0.00081 19.3 0.1 0.0013 18.6 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGC33476.1 - 0.0012 18.3 0.1 0.0031 17.0 0.1 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase Pyr_redox PF00070.27 EGC33476.1 - 0.015 15.9 0.1 0.032 14.8 0.1 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.19 EGC33476.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ApbA PF02558.16 EGC33476.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA RmlD_sub_bind PF04321.17 EGC33476.1 - 0.13 11.3 0.1 0.23 10.5 0.1 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain zf-MIZ PF02891.20 EGC33477.1 - 2.3e-21 75.3 3.9 4.4e-21 74.4 3.9 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.8 EGC33477.1 - 8.7e-07 28.7 0.8 2e-06 27.5 0.8 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Ureide_permease PF07168.11 EGC33477.1 - 8.4 5.0 5.3 4.6 5.9 0.0 2.8 3 0 0 3 3 3 0 Ureide permease TRAPPC9-Trs120 PF08626.11 EGC33478.1 - 9.5e-100 334.7 27.5 9.5e-63 212.1 21.4 2.7 2 1 0 2 2 2 2 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit Foie-gras_1 PF11817.8 EGC33478.1 - 1.7 8.1 4.1 0.98 8.9 0.1 2.3 3 0 0 3 3 3 0 Foie gras liver health family 1 Amnionless PF14828.6 EGC33479.1 - 0.0051 15.7 0.8 0.0058 15.5 0.8 1.0 1 0 0 1 1 1 1 Amnionless ETRAMP PF09716.10 EGC33479.1 - 0.057 13.5 9.5 0.79 9.8 3.0 2.6 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 EGC33479.1 - 0.065 13.5 9.1 0.14 12.5 2.5 2.2 2 0 0 2 2 2 0 Orf78 (ac78) Renin_r PF07850.14 EGC33479.1 - 0.47 11.1 3.6 0.37 11.4 1.8 1.9 1 1 0 1 1 1 0 Renin receptor-like protein DUF2232 PF09991.9 EGC33479.1 - 1.2 8.3 4.1 0.54 9.4 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF2149 PF09919.9 EGC33479.1 - 5.2 7.4 6.8 1.2 9.4 1.1 2.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2149) CfAFP PF05264.11 EGC33479.1 - 5.7 6.9 5.2 3.9 7.5 0.6 2.1 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Mid2 PF04478.12 EGC33480.1 - 0.0094 15.8 1.9 0.029 14.2 1.5 2.0 1 1 1 2 2 2 1 Mid2 like cell wall stress sensor MtrF PF09472.10 EGC33480.1 - 0.18 11.2 1.8 0.4 10.1 1.8 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Syndecan PF01034.20 EGC33480.1 - 0.2 11.6 0.8 0.39 10.7 0.8 1.4 1 0 0 1 1 1 0 Syndecan domain Gly_acyl_tr_C PF08444.10 EGC33481.1 - 4.4e-05 23.6 0.0 0.00012 22.2 0.0 1.7 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.10 EGC33481.1 - 5.2e-05 23.1 0.0 0.00012 21.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein GNAT_acetyltran PF12746.7 EGC33481.1 - 0.0009 18.9 0.1 0.0021 17.6 0.0 1.9 2 1 0 2 2 2 1 GNAT acetyltransferase PKcGMP_CC PF16808.5 EGC33481.1 - 0.014 15.2 1.3 0.039 13.8 1.3 1.8 1 0 0 1 1 1 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Acetyltransf_7 PF13508.7 EGC33481.1 - 0.014 15.8 0.0 0.032 14.6 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PLA2_B PF01735.18 EGC33481.1 - 0.021 13.2 1.4 0.03 12.7 0.1 1.8 2 0 0 2 2 2 0 Lysophospholipase catalytic domain Acetyltransf_3 PF13302.7 EGC33481.1 - 0.091 13.4 0.0 0.24 12.1 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC33481.1 - 0.11 12.7 0.0 0.24 11.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Actin PF00022.19 EGC33482.1 - 3e-152 507.0 0.0 9.6e-152 505.3 0.0 1.6 1 1 0 1 1 1 1 Actin SH3_2 PF07653.17 EGC33485.1 - 1.6e-10 40.5 0.0 2.3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGC33485.1 - 0.00012 21.9 0.1 0.00012 21.9 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain MMACHC PF16690.5 EGC33486.1 - 2e-15 57.0 0.3 4.1e-15 56.0 0.3 1.5 1 1 0 1 1 1 1 Methylmalonic aciduria and homocystinuria type C family RIFIN PF02009.16 EGC33487.1 - 0.024 14.6 19.8 0.21 11.5 8.6 2.1 2 0 0 2 2 2 0 Rifin Utp14 PF04615.13 EGC33487.1 - 0.1 11.2 38.5 0.12 11.0 38.5 1.0 1 0 0 1 1 1 0 Utp14 protein CLN3 PF02487.17 EGC33487.1 - 0.42 9.6 27.0 7.7e+03 -4.4 27.0 2.3 1 1 0 1 1 1 0 CLN3 protein LAP1C PF05609.12 EGC33487.1 - 1.3 8.1 40.8 2.2 7.3 40.8 1.3 1 1 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) GREB1 PF15782.5 EGC33487.1 - 1.4 5.9 28.2 1.8 5.6 28.2 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Mpp10 PF04006.12 EGC33487.1 - 5.7 5.3 56.7 0.034 12.6 22.3 2.0 2 0 0 2 2 2 0 Mpp10 protein SID-1_RNA_chan PF13965.6 EGC33487.1 - 8.9 4.6 22.1 0.28 9.5 3.3 2.1 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 AA_permease_2 PF13520.6 EGC33488.1 - 3.2e-35 121.8 46.1 4.4e-35 121.3 46.1 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC33488.1 - 6.5e-22 77.8 37.0 9.4e-22 77.2 37.0 1.2 1 0 0 1 1 1 1 Amino acid permease Baculo_11_kDa PF06143.11 EGC33488.1 - 0.75 9.4 4.6 33 4.1 0.0 3.8 3 1 0 3 3 3 0 Baculovirus 11 kDa family S_4TM PF18159.1 EGC33488.1 - 4.8 6.4 6.5 18 4.5 0.6 2.6 2 0 0 2 2 2 0 SMODS-associating 4TM effector domain MBOAT PF03062.19 EGC33489.1 - 3.5e-25 89.1 22.6 3.5e-25 89.1 22.6 1.4 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.6 EGC33489.1 - 0.00067 19.9 7.4 0.0015 18.8 7.4 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family DUF4679 PF15728.5 EGC33489.1 - 2.2 7.2 7.5 3.4 6.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4679) PRK PF00485.18 EGC33490.1 - 1.3e-14 54.5 2.1 7.4e-13 48.7 2.1 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.21 EGC33490.1 - 9.8e-14 51.7 0.0 1.9e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 CYTH domain NB-ARC PF00931.22 EGC33490.1 - 0.0046 16.2 0.0 0.0098 15.1 0.0 1.6 1 0 0 1 1 1 1 NB-ARC domain AAA_18 PF13238.6 EGC33490.1 - 0.015 15.8 0.0 0.043 14.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain Homeodomain PF00046.29 EGC33490.1 - 0.015 15.1 0.2 0.045 13.6 0.1 1.9 1 1 0 1 1 1 0 Homeodomain ABC_tran PF00005.27 EGC33490.1 - 0.025 15.1 2.0 0.063 13.8 2.0 2.0 1 1 0 1 1 1 0 ABC transporter TsaE PF02367.17 EGC33490.1 - 0.078 13.0 0.2 9 6.3 0.0 2.5 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE CotJB PF12652.7 EGC33491.1 - 1.2 9.4 9.8 0.14 12.4 1.2 3.7 3 0 0 3 3 3 0 CotJB protein Nodulin_late PF07127.11 EGC33492.1 - 0.014 15.7 0.3 0.014 15.7 0.3 1.8 2 0 0 2 2 2 0 Late nodulin protein POP1 PF06978.11 EGC33493.1 - 3.4e-37 128.4 27.9 1.9e-20 73.8 3.3 3.3 3 1 1 4 4 4 2 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.12 EGC33493.1 - 2.1e-27 95.3 0.2 2.1e-27 95.3 0.2 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.21 EGC33493.1 - 0.0044 16.4 0.0 1.5 8.1 0.0 3.0 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain EB PF01683.18 EGC33494.1 - 0.0025 18.1 27.8 0.45 10.8 7.8 3.8 1 1 3 4 4 4 3 EB module Dickkopf_N PF04706.12 EGC33494.1 - 0.007 16.8 11.0 0.007 16.8 11.0 3.4 2 1 1 3 3 3 2 Dickkopf N-terminal cysteine-rich region DUF2431 PF10354.9 EGC33495.1 - 3.6e-18 66.4 5.5 8.5e-15 55.4 5.5 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF2431) NdhO PF11910.8 EGC33495.1 - 0.15 12.3 0.1 0.84 9.9 0.1 2.2 3 0 0 3 3 3 0 Cyanobacterial and plant NDH-1 subunit O Transglut_core PF01841.19 EGC33496.1 - 6e-22 78.2 0.0 6.7e-11 42.6 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase-like superfamily DUF853 PF05872.12 EGC33496.1 - 2.7 6.5 6.5 4.5 5.7 6.5 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TBCA PF02970.16 EGC33497.1 - 2.8e-23 82.1 3.1 3.5e-23 81.7 3.1 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF4300 PF14133.6 EGC33497.1 - 0.0049 16.6 1.5 0.0051 16.6 1.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4300) Prot_ATP_ID_OB PF16450.5 EGC33497.1 - 0.11 12.5 0.1 0.2 11.6 0.1 1.4 1 0 0 1 1 1 0 Proteasomal ATPase OB C-terminal domain TMEM132D_C PF15706.5 EGC33498.1 - 0.0066 16.2 1.5 0.014 15.2 1.5 1.5 1 0 0 1 1 1 1 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term ACOX PF01756.19 EGC33499.1 - 2.2e-19 69.7 0.2 4.8e-19 68.6 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGC33499.1 - 4.6e-13 49.2 0.0 1e-12 48.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC33499.1 - 0.00025 21.3 0.0 0.00067 19.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.6 EGC33499.1 - 0.00065 20.2 0.0 0.0015 19.1 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF3584 PF12128.8 EGC33500.1 - 0.00047 17.8 26.8 0.00063 17.4 26.8 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) Macoilin PF09726.9 EGC33500.1 - 0.073 11.6 25.7 0.097 11.2 25.7 1.1 1 0 0 1 1 1 0 Macoilin family APG6_N PF17675.1 EGC33500.1 - 0.19 12.2 37.3 0.17 12.4 18.4 3.0 2 1 1 3 3 3 0 Apg6 coiled-coil region Spc7 PF08317.11 EGC33500.1 - 0.19 10.5 32.4 0.048 12.5 28.2 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF3450 PF11932.8 EGC33500.1 - 0.22 10.8 29.9 0.79 9.0 13.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMPIT PF07851.13 EGC33500.1 - 0.28 10.4 25.8 0.3 10.3 15.6 2.5 1 1 1 2 2 2 0 TMPIT-like protein Nup54 PF13874.6 EGC33500.1 - 0.39 10.8 16.5 1.2 9.2 16.5 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 UPF0242 PF06785.11 EGC33500.1 - 0.39 10.8 42.6 0.22 11.6 35.4 3.0 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus HalX PF08663.10 EGC33500.1 - 0.66 10.3 6.7 0.42 11.0 2.7 2.6 1 1 1 2 2 2 0 HalX domain DUF2203 PF09969.9 EGC33500.1 - 2.2 9.0 19.6 0.78 10.5 3.2 2.7 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) HrpB7 PF09486.10 EGC33500.1 - 2.5 8.5 11.0 54 4.1 11.0 2.2 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) HAUS6_N PF14661.6 EGC33500.1 - 2.6 7.6 27.4 1e+03 -0.9 27.2 2.7 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DUF1664 PF07889.12 EGC33500.1 - 6.9 6.7 21.0 0.86 9.7 6.5 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) IFT20 PF14931.6 EGC33500.1 - 8.5 6.6 31.6 1.2 9.3 7.6 3.2 1 1 1 2 2 2 0 Intraflagellar transport complex B, subunit 20 LIM PF00412.22 EGC33501.1 - 1.2e-32 111.9 32.7 3.5e-13 49.5 5.0 3.0 3 0 0 3 3 3 3 LIM domain zinc-ribbons_6 PF07191.12 EGC33501.1 - 0.0012 18.8 24.6 0.24 11.4 6.2 4.3 2 2 1 3 3 3 3 zinc-ribbons Cmc1 PF08583.10 EGC33501.1 - 0.0085 16.1 0.4 0.022 14.8 0.4 1.7 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like DUF2256 PF10013.9 EGC33501.1 - 0.97 9.6 0.1 0.97 9.6 0.1 4.4 7 0 0 7 7 7 0 Uncharacterized protein conserved in bacteria (DUF2256) SP2 PF03014.14 EGC33501.1 - 5.6 5.2 5.7 0.65 8.3 1.8 1.4 2 0 0 2 2 2 0 Structural protein 2 zf-met PF12874.7 EGC33501.1 - 5.9 7.4 14.7 7.5 7.1 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Iso_dh PF00180.20 EGC33503.1 - 1.4e-102 343.4 0.1 1.7e-102 343.1 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase OTU PF02338.19 EGC33504.1 - 1.4e-06 28.8 0.0 2.7e-06 27.9 0.0 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease HNH PF01844.23 EGC33504.1 - 0.018 15.2 0.0 0.052 13.7 0.0 1.8 1 0 0 1 1 1 0 HNH endonuclease PSD2 PF07624.11 EGC33504.1 - 0.035 13.9 0.0 0.065 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) CHCH PF06747.13 EGC33505.1 - 1.6e-05 24.9 1.2 2.1e-05 24.5 1.2 1.2 1 0 0 1 1 1 1 CHCH domain MTCP1 PF08991.10 EGC33505.1 - 0.00044 20.4 0.4 0.0006 20.0 0.4 1.3 1 0 0 1 1 1 1 Mature-T-Cell Proliferation I type CX9C PF16860.5 EGC33505.1 - 0.034 14.2 0.7 0.046 13.7 0.7 1.2 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, NDUF_B7 PF05676.13 EGC33505.1 - 0.079 12.7 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Amino_oxidase PF01593.24 EGC33507.1 - 9e-30 104.3 0.0 1.1e-29 104.1 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC33507.1 - 2.8e-08 33.9 0.0 6.5e-08 32.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGC33507.1 - 0.012 15.2 0.0 0.04 13.5 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAD_binding_9 PF13454.6 EGC33507.1 - 0.024 14.6 0.0 0.84 9.6 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding Acetyltransf_1 PF00583.25 EGC33508.1 - 0.071 13.3 0.0 0.26 11.6 0.0 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Apis_Csd PF11671.8 EGC33508.1 - 4.1 7.4 10.6 7.7 6.5 10.6 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein zf-TRM13_CCCH PF11722.8 EGC33509.1 - 0.94 9.3 12.8 1.7 8.5 0.2 3.9 4 0 0 4 4 4 0 CCCH zinc finger in TRM13 protein CFEM PF05730.11 EGC33509.1 - 1.2 9.2 13.2 0.15 12.2 6.5 2.6 2 1 0 2 2 2 0 CFEM domain DEAD PF00270.29 EGC33510.1 - 3.6e-49 166.9 0.1 1.4e-47 161.7 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC33510.1 - 2.7e-19 69.5 0.0 2.7e-19 69.5 0.0 3.2 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGC33510.1 - 1.9e-13 50.4 0.5 4.3e-13 49.3 0.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RNase_PH PF01138.21 EGC33511.1 - 2.2e-36 125.3 0.3 2.9e-36 124.9 0.3 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGC33511.1 - 0.0094 16.0 0.1 0.026 14.6 0.1 1.8 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 TIG PF01833.24 EGC33512.1 - 2.2e-06 27.6 8.4 4.1e-05 23.6 2.2 4.5 5 1 0 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC33512.1 - 0.0012 19.1 9.0 0.0012 19.1 9.0 3.2 2 0 0 2 2 2 1 EGF-like domain hEGF PF12661.7 EGC33512.1 - 0.17 12.6 12.9 0.051 14.2 2.1 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF LRR_6 PF13516.6 EGC33512.1 - 0.25 11.5 3.2 0.2 11.8 0.4 2.5 2 0 0 2 2 2 0 Leucine Rich repeat EGF_alliinase PF04863.13 EGC33512.1 - 4.8 7.7 17.8 0.81 10.1 2.4 3.7 3 0 0 3 3 3 0 Alliinase EGF-like domain Calcipressin PF04847.12 EGC33513.1 - 2e-12 47.3 0.2 3.9e-12 46.3 0.2 1.6 1 0 0 1 1 1 1 Calcipressin CENP-M PF11111.8 EGC33513.1 - 0.0059 15.8 0.9 1.5 8.0 0.1 2.5 2 1 0 2 2 2 2 Centromere protein M (CENP-M) Aminotran_1_2 PF00155.21 EGC33514.1 - 1.4e-51 175.8 0.0 1.8e-51 175.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGC33514.1 - 0.0018 17.3 0.0 0.0027 16.7 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGC33514.1 - 0.0052 16.1 0.0 0.013 14.8 0.0 1.5 1 1 0 1 1 1 1 Beta-eliminating lyase Rad60-SLD PF11976.8 EGC33515.1 - 0.0002 21.1 0.0 0.00096 18.9 0.0 2.2 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like p450 PF00067.22 EGC33516.1 - 7.9e-48 163.3 0.1 9.8e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 EF-G-binding_N PF07299.11 EGC33516.1 - 0.066 13.7 1.0 0.42 11.2 0.3 2.4 2 0 0 2 2 2 0 Elongation factor G-binding protein, N-terminal Copine PF07002.16 EGC33517.1 - 3.5e-65 219.5 0.0 5e-65 219.0 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC33517.1 - 5e-22 78.1 0.0 1.6e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC33517.1 - 9e-06 25.9 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EGC33517.1 - 0.008 16.1 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGC33517.1 - 0.011 16.0 0.1 0.022 15.0 0.1 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain OTU PF02338.19 EGC33518.1 - 6.1e-11 42.9 0.0 1.2e-10 42.0 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF3759 PF12585.8 EGC33518.1 - 0.054 13.5 0.4 1.8 8.6 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) DUF3330 PF11809.8 EGC33518.1 - 0.57 10.3 3.8 0.68 10.0 0.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF3330) ScsC_N PF18312.1 EGC33518.1 - 8.9 6.2 14.7 8.6 6.3 2.6 2.8 3 0 0 3 3 3 0 Copper resistance protein ScsC N-terminal domain FNIP PF05725.12 EGC33520.1 - 6.4e-57 189.5 64.7 2.1e-13 50.2 0.3 9.0 7 2 2 9 9 9 8 FNIP Repeat COX7C PF02935.16 EGC33521.1 - 8.5 6.7 9.0 4.7 7.5 1.4 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit VIIc Vps54 PF07928.12 EGC33522.1 - 0.026 15.0 2.0 9.8 6.6 0.1 3.7 3 0 0 3 3 3 0 Vps54-like protein FNIP PF05725.12 EGC33523.1 - 2.6e-45 152.3 56.5 5.4e-09 36.1 6.0 8.1 5 2 4 9 9 9 9 FNIP Repeat LRR_5 PF13306.6 EGC33523.1 - 3.3e-06 27.1 16.9 0.0074 16.2 6.2 3.6 2 1 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF1389 PF07146.11 EGC33523.1 - 0.95 8.7 7.6 0.41 9.9 1.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1389) DUF5367 PF17329.2 EGC33524.1 - 0.065 13.4 0.2 7.6 6.7 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5367) DUF2431 PF10354.9 EGC33524.1 - 0.071 13.4 1.0 0.52 10.6 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF2431) Scramblase PF03803.15 EGC33525.1 - 5.3e-22 78.2 2.7 6.7e-22 77.9 2.7 1.1 1 0 0 1 1 1 1 Scramblase Copine PF07002.16 EGC33526.1 - 2.3e-65 220.1 0.0 3.2e-65 219.6 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC33526.1 - 1e-19 70.7 0.0 5.1e-12 46.0 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC33526.1 - 8.2e-07 29.3 0.0 1.5e-06 28.4 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC33526.1 - 0.012 15.9 0.2 0.022 15.0 0.2 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain VWA_3 PF13768.6 EGC33526.1 - 0.12 12.3 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain TIG PF01833.24 EGC33528.1 - 0.00014 21.8 2.0 0.00065 19.7 2.0 2.2 1 0 0 1 1 1 1 IPT/TIG domain EGF_2 PF07974.13 EGC33528.1 - 0.00037 20.8 41.2 0.0014 18.9 13.4 2.9 2 0 0 2 2 2 2 EGF-like domain DUF4448 PF14610.6 EGC33528.1 - 0.023 14.4 0.1 0.056 13.2 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) ECSCR PF15820.5 EGC33528.1 - 0.69 9.8 4.8 0.28 11.0 0.4 2.5 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DHR10 PF18595.1 EGC33529.1 - 0.015 15.4 8.0 0.015 15.4 8.0 2.3 2 1 0 2 2 2 0 Designed helical repeat protein 10 domain TACC_C PF05010.14 EGC33529.1 - 0.068 12.9 21.2 0.034 13.9 6.1 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal DUF3713 PF12506.8 EGC33529.1 - 0.16 12.3 12.2 0.47 10.8 11.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) LUC7 PF03194.15 EGC33529.1 - 0.84 9.3 12.5 1.2 8.7 12.5 1.3 1 1 0 1 1 1 0 LUC7 N_terminus EMC3_TMCO1 PF01956.16 EGC33529.1 - 0.92 9.2 10.2 8.1 6.1 10.2 2.0 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like DUF724 PF05266.14 EGC33529.1 - 9.3 6.0 16.5 6.2 6.6 5.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) EGF_2 PF07974.13 EGC33532.1 - 0.087 13.2 1.1 0.18 12.2 1.1 1.6 1 0 0 1 1 1 0 EGF-like domain Aminotran_5 PF00266.19 EGC33533.1 - 6.7e-22 77.9 0.0 2e-19 69.8 0.0 2.4 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.20 EGC33533.1 - 3e-17 62.9 0.0 7.6e-17 61.6 0.0 1.7 1 0 0 1 1 1 1 PP-loop family LD_cluster2 PF18163.1 EGC33533.1 - 0.0075 15.8 0.3 0.014 14.9 0.3 1.4 1 0 0 1 1 1 1 SLOG cluster2 zf-RING_2 PF13639.6 EGC33534.1 - 2.3e-08 34.2 12.9 2.3e-08 34.2 12.9 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33534.1 - 3.2e-08 33.3 10.4 3.2e-08 33.3 10.4 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC33534.1 - 2.7e-06 27.1 9.1 4.8e-06 26.3 9.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33534.1 - 3.2e-06 26.9 12.8 7.2e-06 25.8 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33534.1 - 0.00015 22.0 6.8 0.00048 20.3 6.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC33534.1 - 0.0014 18.4 5.5 0.0027 17.5 5.5 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGC33534.1 - 0.018 15.2 12.1 0.042 14.0 12.1 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC33534.1 - 0.021 14.6 12.3 0.048 13.4 12.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC33534.1 - 0.064 13.3 2.7 0.12 12.4 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGC33534.1 - 0.14 12.2 10.5 0.4 10.7 10.5 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC33534.1 - 0.56 10.1 9.8 1.5 8.7 9.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGC33534.1 - 0.87 9.3 7.5 1.5 8.5 7.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGC33534.1 - 2.6 7.8 13.8 0.1 12.4 7.3 2.0 2 0 0 2 2 2 0 RING-like zinc finger zf-RING_5 PF14634.6 EGC33534.1 - 3.8 7.6 16.7 0.13 12.2 10.0 2.0 2 0 0 2 2 2 0 zinc-RING finger domain Borrelia_P83 PF05262.11 EGC33534.1 - 7.4 4.9 28.6 11 4.4 28.6 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PKD_channel PF08016.12 EGC33535.1 - 4e-43 147.7 12.5 4e-43 147.7 12.5 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EGC33535.1 - 3.2e-07 29.8 23.0 3.2e-07 29.8 23.0 2.2 2 0 0 2 2 2 1 Ion transport protein Baculo_11_kDa PF06143.11 EGC33535.1 - 0.071 12.7 6.1 1.3 8.6 0.2 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family IL11 PF07400.11 EGC33535.1 - 0.092 12.4 0.2 0.2 11.3 0.2 1.5 1 0 0 1 1 1 0 Interleukin 11 FUSC PF04632.12 EGC33535.1 - 1 7.8 8.2 1.6 7.2 8.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Calpain_III PF01067.22 EGC33536.1 - 2e-36 125.3 0.6 4e-15 56.3 0.0 3.8 4 0 0 4 4 4 3 Calpain large subunit, domain III C2 PF00168.30 EGC33536.1 - 5.3e-10 39.5 1.0 4.8e-07 30.0 0.1 3.5 2 1 1 3 3 3 2 C2 domain RNase_J_C PF17770.1 EGC33537.1 - 0.4 11.8 1.7 8.3 7.5 0.7 2.1 1 1 0 2 2 2 0 Ribonuclease J C-terminal domain Macoilin PF09726.9 EGC33537.1 - 1.2 7.6 8.7 1.4 7.4 8.7 1.0 1 0 0 1 1 1 0 Macoilin family Translin PF01997.16 EGC33538.1 - 2.7e-45 154.9 2.9 3.1e-45 154.7 2.9 1.0 1 0 0 1 1 1 1 Translin family Lipoprotein_7 PF01540.16 EGC33538.1 - 0.0043 16.4 1.8 0.029 13.7 1.8 1.9 1 1 0 1 1 1 1 Adhesin lipoprotein PLU-1 PF08429.11 EGC33538.1 - 0.027 13.6 3.1 0.074 12.2 0.2 2.0 2 0 0 2 2 2 0 PLU-1-like protein DUF2730 PF10805.8 EGC33538.1 - 0.052 13.6 2.0 0.25 11.4 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2730) DUF4279 PF14106.6 EGC33538.1 - 0.056 13.6 0.9 0.26 11.5 0.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) DUF2371 PF10177.9 EGC33539.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 1.9 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) NPR3 PF03666.13 EGC33539.1 - 0.0014 17.5 0.1 0.0014 17.5 0.1 2.1 2 0 0 2 2 2 1 Nitrogen Permease regulator of amino acid transport activity 3 ETRAMP PF09716.10 EGC33539.1 - 0.0016 18.5 0.0 0.035 14.2 0.0 2.5 1 1 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) DUF4199 PF13858.6 EGC33539.1 - 0.0029 18.0 7.4 0.008 16.6 0.0 2.5 2 1 0 2 2 2 1 Protein of unknown function (DUF4199) Peroxin-13_N PF04088.13 EGC33539.1 - 0.0058 16.9 0.0 4.2 7.6 0.1 2.5 2 0 0 2 2 2 2 Peroxin 13, N-terminal region OATP PF03137.20 EGC33539.1 - 0.011 14.0 0.1 0.055 11.7 0.1 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 2HCT PF03390.15 EGC33539.1 - 0.012 14.2 1.5 0.019 13.6 0.3 1.7 2 0 0 2 2 2 0 2-hydroxycarboxylate transporter family DUF1943 PF09172.11 EGC33539.1 - 0.058 12.6 0.9 1.2 8.3 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Ycf70 PF17382.2 EGC33539.1 - 2.1 8.8 5.7 1.1 9.7 0.3 2.9 1 1 3 4 4 4 0 Uncharacterized Ycf70-like CbtA PF09490.10 EGC33539.1 - 2.8 7.6 0.0 2.8 7.6 0.0 3.9 2 1 0 2 2 1 0 Probable cobalt transporter subunit (CbtA) DUF5090 PF17009.5 EGC33539.1 - 6.6 6.6 14.5 1.8 8.5 11.4 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF5090) SARAF PF06682.12 EGC33539.1 - 8.2 6.0 11.4 0.17 11.5 0.4 2.3 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Pkinase PF00069.25 EGC33540.1 - 1.8e-32 112.8 0.1 7.1e-32 110.8 0.1 2.1 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.32 EGC33540.1 - 9.7e-12 45.2 2.6 0.0003 21.5 0.1 4.4 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EGC33540.1 - 1.9e-11 43.8 0.0 5.5e-11 42.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Glyco_hydro_38N PF01074.22 EGC33541.1 - 4.4e-75 252.7 6.6 8.5e-75 251.8 6.6 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGC33541.1 - 6.2e-21 75.5 3.1 1.6e-20 74.1 3.1 1.8 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGC33541.1 - 3.1e-17 62.5 0.0 1e-16 60.8 0.0 2.0 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGC33541.1 - 0.00063 19.8 0.1 0.0022 18.1 0.1 2.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain RabGAP-TBC PF00566.18 EGC33543.1 - 7e-44 150.1 9.4 3.2e-43 147.9 1.9 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Macoilin PF09726.9 EGC33543.1 - 8.1 4.9 12.0 0.23 10.0 5.5 1.5 2 0 0 2 2 2 0 Macoilin family BK_channel_a PF03493.18 EGC33544.1 - 7.3e-21 74.2 0.8 4.9e-20 71.5 0.0 2.7 2 1 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.16 EGC33544.1 - 8.7e-16 57.7 3.4 2.4e-15 56.2 3.4 1.8 1 0 0 1 1 1 1 Ion channel Ion_trans PF00520.31 EGC33544.1 - 2.9e-11 43.1 12.4 2.9e-11 43.1 12.4 2.9 3 1 0 3 3 3 1 Ion transport protein TrkA_N PF02254.18 EGC33544.1 - 9.5e-07 29.1 0.0 0.003 17.8 0.0 2.8 2 0 0 2 2 2 2 TrkA-N domain Lig_chan PF00060.26 EGC33544.1 - 0.0091 15.8 2.4 0.038 13.8 0.6 2.4 2 0 0 2 2 2 1 Ligand-gated ion channel Complex1_LYR PF05347.15 EGC33545.1 - 6.9e-12 45.2 0.5 1.2e-11 44.5 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC33545.1 - 0.0029 18.3 1.2 0.0035 18.0 1.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like PTS_IIA PF02255.16 EGC33545.1 - 0.095 12.8 0.3 0.16 12.1 0.3 1.4 1 1 0 1 1 1 0 PTS system, Lactose/Cellobiose specific IIA subunit ABC_membrane PF00664.23 EGC33546.1 - 7.2e-125 416.1 22.7 9.8e-64 215.6 3.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC33546.1 - 1.6e-70 236.0 0.1 1.9e-34 119.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGC33546.1 - 7.5e-15 55.0 0.0 7.3e-07 28.8 0.0 3.1 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC33546.1 - 2.3e-05 24.0 1.4 0.13 12.0 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC33546.1 - 0.00012 22.0 0.0 0.52 10.2 0.0 2.7 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGC33546.1 - 0.00016 21.9 0.3 0.35 11.1 0.0 3.3 2 2 0 2 2 2 2 AAA domain SbcCD_C PF13558.6 EGC33546.1 - 0.00019 21.6 2.7 1.3 9.3 0.3 3.9 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.9 EGC33546.1 - 0.0019 17.1 0.8 0.46 9.2 0.0 2.5 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_7 PF12775.7 EGC33546.1 - 0.0025 17.3 0.3 3.4 7.1 0.0 2.9 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_16 PF13191.6 EGC33546.1 - 0.016 15.6 0.1 4 7.8 0.0 2.7 2 1 0 2 2 2 0 AAA ATPase domain AAA_24 PF13479.6 EGC33546.1 - 0.035 13.8 0.0 1.5 8.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC33546.1 - 0.037 13.7 4.4 8.7 6.0 0.0 4.0 3 2 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGC33546.1 - 0.1 11.8 0.8 6 6.1 0.0 3.1 4 0 0 4 4 4 0 Zeta toxin AAA_5 PF07728.14 EGC33546.1 - 0.23 11.4 1.0 43 4.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_21 PF13304.6 EGC33546.1 - 0.4 10.5 3.5 6 6.6 0.3 3.2 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Cation_efflux PF01545.21 EGC33547.1 - 7.1e-29 101.0 12.2 9e-29 100.6 12.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGC33547.1 - 3.5e-12 46.3 0.0 6e-12 45.5 0.0 1.3 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter Lipocalin_4 PF13648.6 EGC33548.1 - 1.3 10.0 6.0 1.3 10.0 3.0 2.5 1 1 1 2 2 2 0 Lipocalin-like domain DEAD PF00270.29 EGC33549.1 - 1.4e-45 155.2 0.1 4.4e-45 153.6 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC33549.1 - 3.9e-28 98.0 0.0 3.9e-28 98.0 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain SWI2_SNF2 PF18766.1 EGC33549.1 - 0.0038 16.9 7.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGC33549.1 - 0.27 11.5 1.6 1.4 9.2 0.2 2.7 2 1 0 2 2 2 0 AAA domain Lactamase_B_6 PF16661.5 EGC33550.1 - 7.9e-50 169.0 0.0 1.9e-49 167.7 0.0 1.6 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EGC33550.1 - 2.4e-18 66.4 0.0 1.6e-17 63.8 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.6 EGC33550.1 - 2.1e-17 63.8 8.0 3.8e-14 53.2 0.0 3.9 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.12 EGC33550.1 - 4.3e-08 33.0 0.0 1.3e-07 31.4 0.0 1.9 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGC33550.1 - 2.2e-05 24.5 0.0 4.3e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC33550.1 - 0.002 17.7 0.0 0.0037 16.8 0.0 1.4 1 0 0 1 1 1 1 Beta-lactamase superfamily domain GDPD PF03009.17 EGC33550.1 - 0.039 13.7 0.2 0.1 12.3 0.2 1.7 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family WWE PF02825.20 EGC33550.1 - 0.32 11.6 1.3 1.7 9.3 0.5 2.7 2 0 0 2 2 2 0 WWE domain GTP_EFTU PF00009.27 EGC33551.1 - 1.9e-25 89.5 0.0 8.2e-25 87.5 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGC33551.1 - 1.4e-07 31.7 0.1 3.9e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC33551.1 - 4.1e-05 23.6 0.9 0.0001 22.3 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC33551.1 - 0.0003 20.3 1.0 0.021 14.3 1.0 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC33551.1 - 0.0058 16.0 1.7 0.02 14.2 1.7 1.9 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region RIBIOP_C PF04950.12 EGC33551.1 - 0.085 12.3 3.1 0.31 10.4 2.8 2.0 1 1 0 1 1 1 0 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal PduV-EutP PF10662.9 EGC33551.1 - 0.14 11.9 3.9 6.2 6.6 0.0 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation TIG PF01833.24 EGC33554.1 - 3.4e-15 55.9 1.4 1.1e-14 54.2 1.4 2.0 1 0 0 1 1 1 1 IPT/TIG domain Tup_N PF08581.10 EGC33555.1 - 0.0031 17.8 7.3 0.0031 17.8 7.3 7.1 4 3 3 7 7 7 1 Tup N-terminal YabA PF06156.13 EGC33555.1 - 6.1 7.5 61.3 0.37 11.5 10.9 5.3 3 1 2 5 5 5 0 Initiation control protein YabA FNIP PF05725.12 EGC33556.1 - 7e-159 515.9 45.1 6.7e-16 58.2 0.3 13.3 6 2 6 15 15 15 15 FNIP Repeat Phage_min_tail PF05939.13 EGC33556.1 - 1.1e-08 35.3 1.0 29 5.1 0.0 10.2 5 4 6 12 12 12 1 Phage minor tail protein LRR_1 PF00560.33 EGC33556.1 - 0.00028 21.0 0.6 3.3e+02 2.5 0.0 7.9 4 3 1 5 5 5 0 Leucine Rich Repeat Peptidase_S78 PF04586.17 EGC33556.1 - 0.0016 18.7 0.0 56 3.9 0.0 5.6 3 2 0 4 4 4 0 Caudovirus prohead serine protease Nrap_D2 PF17403.2 EGC33557.1 - 0.0018 18.0 0.0 0.0025 17.6 0.0 1.2 1 0 0 1 1 1 1 Nrap protein PAP/OAS-like domain OAS1_C PF10421.9 EGC33557.1 - 0.0023 17.4 0.0 0.0027 17.2 0.0 1.1 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus bZIP_1 PF00170.21 EGC33558.1 - 2.5 8.3 8.4 1.8 8.7 1.5 3.7 2 0 0 2 2 2 0 bZIP transcription factor PAP_assoc PF03828.19 EGC33559.1 - 0.0001 22.4 0.4 0.0001 22.4 0.4 2.6 3 0 0 3 3 3 1 Cid1 family poly A polymerase PhoLip_ATPase_C PF16212.5 EGC33560.1 - 6.6e-50 170.2 22.9 6.6e-50 170.2 22.9 3.1 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal E1-E2_ATPase PF00122.20 EGC33560.1 - 4e-14 52.5 0.0 4e-14 52.5 0.0 2.3 3 0 0 3 3 3 1 E1-E2 ATPase PhoLip_ATPase_N PF16209.5 EGC33560.1 - 8e-12 44.7 9.6 3.2e-11 42.7 9.6 2.1 1 0 0 1 1 1 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGC33560.1 - 1.3e-11 44.4 0.0 2e-09 37.4 0.0 2.7 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC33560.1 - 4.3e-10 40.2 2.8 0.0025 18.2 0.0 3.2 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC33560.1 - 9.2e-05 22.3 0.1 9.2e-05 22.3 0.1 2.5 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box PF00646.33 EGC33561.1 - 0.0014 18.4 1.4 0.044 13.7 1.2 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.7 EGC33561.1 - 0.11 12.4 0.2 0.3 11.0 0.2 1.7 1 0 0 1 1 1 0 F-box-like Bro-N PF02498.17 EGC33561.1 - 6.7 7.5 10.9 1 10.1 1.0 3.0 2 0 0 2 2 2 0 BRO family, N-terminal domain GAPT PF11770.8 EGC33563.1 - 0.0091 15.9 0.3 0.0091 15.9 0.3 2.2 2 0 0 2 2 2 1 GRB2-binding adapter (GAPT) EGF_2 PF07974.13 EGC33563.1 - 0.061 13.7 9.9 0.17 12.3 9.9 1.8 1 0 0 1 1 1 0 EGF-like domain RGS PF00615.19 EGC33564.1 - 0.044 14.1 2.4 0.073 13.3 2.4 1.5 1 1 0 1 1 1 0 Regulator of G protein signaling domain FRB_dom PF08771.11 EGC33564.1 - 0.11 12.9 2.2 0.22 12.0 0.6 1.9 1 1 1 2 2 2 0 FKBP12-rapamycin binding domain HAUS2 PF15003.6 EGC33564.1 - 0.23 11.2 4.2 0.69 9.6 4.2 1.9 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 2 HBM PF16591.5 EGC33564.1 - 0.24 10.8 3.8 0.62 9.4 0.8 2.1 1 1 1 2 2 2 0 Helical bimodular sensor domain C2 PF00168.30 EGC33565.1 - 9.9e-18 64.3 0.1 2.3e-17 63.2 0.1 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 EGC33565.1 - 7.3e-11 42.4 2.9 3.1e-05 24.2 0.0 3.9 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain DUF3932 PF13068.6 EGC33565.1 - 0.04 14.2 2.1 1.3 9.3 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3932) RBFA PF02033.18 EGC33566.1 - 0.00013 22.3 10.4 0.0032 17.9 1.2 3.8 3 0 0 3 3 3 2 Ribosome-binding factor A DDE_Tnp_1 PF01609.21 EGC33566.1 - 0.014 15.0 2.1 0.048 13.3 2.1 1.9 1 0 0 1 1 1 0 Transposase DDE domain VWA_2 PF13519.6 EGC33567.1 - 2.1e-08 34.8 0.0 2.1e-08 34.8 0.0 3.6 3 1 0 3 3 3 1 von Willebrand factor type A domain Presenilin PF01080.17 EGC33567.1 - 3.2 6.4 41.0 5.9 5.6 41.0 1.3 1 0 0 1 1 1 0 Presenilin Asp-B-Hydro_N PF05279.11 EGC33567.1 - 9.6 6.2 22.9 15 5.6 22.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Profilin PF00235.19 EGC33568.1 - 4.1e-21 75.6 0.0 4.5e-21 75.4 0.0 1.0 1 0 0 1 1 1 1 Profilin PglD_N PF17836.1 EGC33568.1 - 0.077 13.6 0.8 1.5 9.5 0.1 2.2 1 1 1 2 2 2 0 PglD N-terminal domain E2F_CC-MB PF16421.5 EGC33569.1 - 3.9e-25 88.0 0.0 3.9e-25 88.0 0.0 3.1 3 0 0 3 3 3 1 E2F transcription factor CC-MB domain E2F_TDP PF02319.20 EGC33569.1 - 1.1e-18 67.0 0.1 3.5e-18 65.4 0.1 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.19 EGC33569.1 - 0.014 15.2 0.0 0.03 14.2 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB TFIIA PF03153.13 EGC33569.1 - 0.051 13.6 50.9 0.45 10.5 10.1 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Ribosomal_60s PF00428.19 EGC33569.1 - 0.09 13.4 2.4 0.17 12.5 0.8 2.2 2 0 0 2 2 2 0 60s Acidic ribosomal protein ADK PF00406.22 EGC33570.1 - 6.8e-62 208.0 0.0 8.5e-62 207.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGC33570.1 - 2.6e-24 86.2 0.1 7.3e-24 84.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain ADK_lid PF05191.14 EGC33570.1 - 4.6e-16 58.5 0.0 1.1e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 Adenylate kinase, active site lid Hydin_ADK PF17213.3 EGC33570.1 - 0.00011 22.6 0.1 0.025 14.9 0.0 2.4 1 1 1 2 2 2 2 Hydin Adenylate kinase-like domain AAA_33 PF13671.6 EGC33570.1 - 0.0021 18.2 0.0 0.0038 17.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain RuvB_N PF05496.12 EGC33570.1 - 0.0088 15.8 0.0 0.026 14.3 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_18 PF13238.6 EGC33570.1 - 0.09 13.3 0.0 0.21 12.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGC33570.1 - 0.1 12.2 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Thymidylate_kin PF02223.17 EGC33570.1 - 0.11 12.1 0.0 7 6.3 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase Torsin PF06309.11 EGC33570.1 - 0.16 12.1 0.0 18 5.4 0.0 3.0 3 0 0 3 3 3 0 Torsin TMA7 PF09072.10 EGC33571.1 - 6.4e-27 94.2 18.4 7.7e-27 93.9 18.4 1.1 1 0 0 1 1 1 1 Translation machinery associated TMA7 rRNA_processing PF08524.11 EGC33572.1 - 6.4e-07 29.5 52.1 6.4e-07 29.5 52.1 3.2 1 1 0 2 2 2 1 rRNA processing SNF2_N PF00176.23 EGC33573.1 - 9.4e-69 231.8 3.6 2.1e-68 230.6 3.6 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC33573.1 - 4.6e-21 75.2 0.0 1.8e-20 73.3 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGC33573.1 - 2e-19 69.2 8.8 9.5e-10 38.3 1.5 4.0 3 0 0 3 3 3 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.6 EGC33573.1 - 3.1e-16 59.6 0.5 3.1e-16 59.6 0.5 3.6 3 1 1 4 4 4 1 Domain of unknown function (DUF4208) ResIII PF04851.15 EGC33573.1 - 5.7e-11 42.7 0.0 5.7e-11 42.7 0.0 3.5 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SLIDE PF09111.10 EGC33573.1 - 0.00046 20.2 0.0 0.00046 20.2 0.0 5.1 6 1 0 6 6 6 1 SLIDE Myb_DNA-binding PF00249.31 EGC33573.1 - 0.0022 18.1 0.0 0.011 15.9 0.0 2.2 1 0 0 1 1 1 1 Myb-like DNA-binding domain CHDCT2 PF08074.11 EGC33573.1 - 0.0087 16.3 2.6 0.039 14.1 0.0 3.3 2 0 0 2 2 2 1 CHDCT2 (NUC038) domain MutS_V PF00488.21 EGC33574.1 - 7.7e-45 153.2 0.1 2.7e-44 151.4 0.1 1.9 1 1 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGC33574.1 - 9.4e-25 88.0 0.1 2.9e-24 86.4 0.1 1.9 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.18 EGC33574.1 - 0.0018 18.6 0.0 0.0018 18.6 0.0 2.5 3 0 0 3 3 3 1 MutS family domain IV AAA_14 PF13173.6 EGC33574.1 - 0.045 13.8 0.0 0.045 13.8 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_22 PF13401.6 EGC33574.1 - 0.063 13.6 0.2 6.8 7.0 0.0 3.5 4 0 0 4 4 4 0 AAA domain Hrs_helical PF12210.8 EGC33574.1 - 0.19 12.3 0.7 12 6.5 0.0 2.7 2 0 0 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate Sec8_exocyst PF04048.14 EGC33575.1 - 2.4e-16 59.9 0.5 2.4e-16 59.9 0.5 3.5 4 0 0 4 4 4 1 Sec8 exocyst complex component specific domain Activator_LAG-3 PF11498.8 EGC33575.1 - 0.54 9.2 15.5 1.2 8.1 15.5 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Androgen_recep PF02166.16 EGC33575.1 - 2.8 6.7 6.2 5 5.9 6.2 1.3 1 0 0 1 1 1 0 Androgen receptor AMP-binding PF00501.28 EGC33576.1 - 1.2e-93 314.0 0.0 1.5e-93 313.7 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC33576.1 - 1.4e-15 58.1 0.0 3.6e-15 56.7 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Band_7 PF01145.25 EGC33577.1 - 3.4e-27 95.6 0.1 6.2e-27 94.7 0.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Adeno_E3_CR2 PF02439.15 EGC33577.1 - 2.4 8.0 5.3 4.6 7.1 5.3 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_C13 PF01650.18 EGC33578.1 - 2.8e-47 161.4 0.0 4.1e-47 160.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family ArgoMid PF16487.5 EGC33578.1 - 0.039 14.2 0.2 0.16 12.2 0.0 2.0 2 0 0 2 2 2 0 Mid domain of argonaute Tctex-1 PF03645.13 EGC33579.1 - 6.5e-32 109.8 2.3 7.4e-32 109.7 2.3 1.0 1 0 0 1 1 1 1 Tctex-1 family CTD_bind PF04818.13 EGC33580.1 - 5.4e-13 49.6 0.3 5.4e-13 49.6 0.3 2.1 2 1 0 2 2 2 1 RNA polymerase II-binding domain. TFIIA PF03153.13 EGC33580.1 - 0.38 10.7 26.9 0.49 10.3 26.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2203 PF09969.9 EGC33580.1 - 0.48 11.1 3.2 0.37 11.5 1.0 1.9 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) eIF_4EBP PF05456.11 EGC33580.1 - 0.96 9.4 0.0 0.96 9.4 0.0 3.1 2 1 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Presenilin PF01080.17 EGC33580.1 - 5.6 5.6 13.5 8.4 5.0 13.5 1.4 1 0 0 1 1 1 0 Presenilin FHA PF00498.26 EGC33581.1 - 1.1e-15 57.7 4.9 2.9e-15 56.3 4.9 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC33581.1 - 1.6e-05 25.1 0.0 0.001 19.3 0.0 2.5 2 1 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain FAM176 PF14851.6 EGC33581.1 - 0.0031 17.2 2.6 1.2 8.8 0.1 2.2 2 0 0 2 2 2 2 FAM176 family DUF4834 PF16118.5 EGC33581.1 - 0.029 15.3 9.7 0.32 12.0 5.6 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Gti1_Pac2 PF09729.9 EGC33581.1 - 0.071 13.2 13.5 0.17 12.0 9.3 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family DUF2457 PF10446.9 EGC33581.1 - 0.081 12.1 10.8 0.098 11.8 1.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2457) Ketoacyl-synt_2 PF13723.6 EGC33581.1 - 1.6 8.3 0.0 1.6 8.3 0.0 2.3 3 0 0 3 3 3 0 Beta-ketoacyl synthase, N-terminal domain POX PF07526.11 EGC33581.1 - 2.5 8.7 6.3 7.6 7.1 3.0 2.2 2 0 0 2 2 2 0 Associated with HOX RPA43_OB PF17875.1 EGC33581.1 - 4.6 7.9 10.6 1.8 9.2 0.1 2.2 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I DUF3854 PF12965.7 EGC33582.1 - 6.4 6.8 6.4 28 4.7 6.4 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) OrsD PF12013.8 EGC33583.1 - 1.4 9.4 3.7 1.4 9.4 0.1 2.4 2 0 0 2 2 2 0 Orsellinic acid/F9775 biosynthesis cluster protein D Peptidase_C1 PF00112.23 EGC33584.1 - 1.7e-84 283.3 3.9 2.3e-84 282.8 3.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC33584.1 - 3.1e-14 53.1 1.7 5.3e-14 52.4 1.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC33584.1 - 0.0034 16.2 1.7 0.017 13.9 0.3 2.1 2 0 0 2 2 2 1 Peptidase C1-like family Peptidase_C1 PF00112.23 EGC33585.1 - 1.2e-83 280.6 6.5 1.6e-83 280.1 6.5 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC33585.1 - 8.6e-14 51.7 2.3 1.4e-13 51.0 2.3 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC33585.1 - 0.00082 18.3 1.1 0.0049 15.7 0.3 2.1 2 0 0 2 2 2 1 Peptidase C1-like family Mid2 PF04478.12 EGC33586.1 - 0.0015 18.4 0.3 0.0058 16.5 0.3 2.0 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor VSP PF03302.13 EGC33586.1 - 0.0026 16.7 0.1 0.0041 16.0 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein DUF4006 PF13179.6 EGC33586.1 - 0.037 13.9 4.5 0.052 13.5 0.1 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF4006) Syndecan PF01034.20 EGC33586.1 - 0.99 9.4 3.0 2.2 8.3 0.3 2.6 2 0 0 2 2 2 0 Syndecan domain Beta_elim_lyase PF01212.21 EGC33587.1 - 3.4e-89 299.0 0.0 4e-89 298.8 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase Cation_ATPase_C PF00689.21 EGC33588.1 - 1.5e-38 132.3 9.2 1.5e-38 132.3 9.2 3.0 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGC33588.1 - 2e-33 115.4 0.0 2e-33 115.4 0.0 4.0 4 0 0 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGC33588.1 - 7e-17 62.4 0.2 3.1e-16 60.3 0.2 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC33588.1 - 6.8e-12 44.9 0.0 1.5e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGC33588.1 - 7.9e-08 32.3 2.6 3.1e-05 23.9 1.0 2.6 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGC33588.1 - 9.4e-08 32.0 0.0 1.9e-06 27.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Actin PF00022.19 EGC33589.1 - 2.2e-124 415.2 0.0 5.8e-124 413.8 0.0 1.6 1 1 0 1 1 1 1 Actin Ist1 PF03398.14 EGC33589.1 - 3.2e-43 147.5 0.5 4.6e-43 147.0 0.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.19 EGC33589.1 - 3.6e-31 108.0 1.5 1.3e-14 54.8 0.0 2.7 3 0 0 3 3 3 2 Filamin/ABP280 repeat Invasin_D3 PF09134.10 EGC33589.1 - 2.2e-05 24.7 3.6 0.018 15.3 0.1 3.3 4 0 0 4 4 4 2 Invasin, domain 3 DUF5011 PF16403.5 EGC33589.1 - 0.94 9.7 5.4 0.59 10.3 1.9 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF5011) Y_Y_Y PF07495.13 EGC33589.1 - 1.1 9.2 5.1 5.2 7.1 0.2 3.3 4 0 0 4 4 4 0 Y_Y_Y domain NOT2_3_5 PF04153.18 EGC33590.1 - 7.7e-28 97.2 3.6 7.7e-28 97.2 3.6 3.6 4 1 0 4 4 4 1 NOT2 / NOT3 / NOT5 family ABC_membrane PF00664.23 EGC33591.1 - 5.6e-128 426.3 18.1 3.3e-65 220.5 4.2 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC33591.1 - 1.6e-68 229.5 0.1 6.7e-35 120.6 0.1 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGC33591.1 - 1.6e-16 60.4 0.0 8.1e-07 28.7 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGC33591.1 - 5e-06 26.5 0.0 0.037 13.9 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_29 PF13555.6 EGC33591.1 - 6.7e-06 25.8 1.4 0.11 12.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain ABC_ATPase PF09818.9 EGC33591.1 - 8.1e-05 21.6 1.9 0.044 12.6 0.0 2.6 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_16 PF13191.6 EGC33591.1 - 9.2e-05 22.9 0.1 0.065 13.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain SbcCD_C PF13558.6 EGC33591.1 - 0.00066 19.9 7.5 0.03 14.6 0.7 4.2 3 2 0 3 3 2 1 Putative exonuclease SbcCD, C subunit AAA_5 PF07728.14 EGC33591.1 - 0.00066 19.7 0.3 17 5.4 0.0 4.4 3 1 1 4 4 4 0 AAA domain (dynein-related subfamily) APS_kinase PF01583.20 EGC33591.1 - 0.0037 17.2 0.0 0.54 10.1 0.0 2.4 2 0 0 2 2 2 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EGC33591.1 - 0.0059 15.9 0.0 0.3 10.3 0.0 2.9 3 0 0 3 3 3 1 Zeta toxin AAA_25 PF13481.6 EGC33591.1 - 0.092 12.3 0.0 3.8 7.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC33591.1 - 0.099 12.3 0.1 19 4.9 0.0 2.9 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC33591.1 - 0.11 12.7 2.7 20 5.5 0.1 3.5 2 2 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC33591.1 - 0.29 11.7 1.3 8 7.0 0.0 3.2 3 0 0 3 3 2 0 AAA domain Peptidase_S49_N PF08496.10 EGC33591.1 - 1.3 9.1 3.6 2.7 8.0 0.6 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal AAA_21 PF13304.6 EGC33591.1 - 2.4 7.9 12.7 7.3 6.3 0.1 4.1 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system MWFE PF15879.5 EGC33592.1 - 6e-13 48.8 0.0 8.6e-13 48.2 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase MWFE subunit RIFIN PF02009.16 EGC33593.1 - 0.2 11.5 0.0 0.2 11.5 0.0 1.6 2 0 0 2 2 2 0 Rifin DUF4064 PF13273.6 EGC33594.1 - 0.0047 17.2 0.2 0.49 10.7 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF4064) DUF4199 PF13858.6 EGC33594.1 - 0.0089 16.4 1.0 1.9 8.8 0.0 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4199) S8_pro-domain PF16470.5 EGC33594.1 - 0.44 11.4 3.8 18 6.2 0.6 2.8 2 0 0 2 2 2 0 Peptidase S8 pro-domain Epimerase PF01370.21 EGC33595.1 - 1e-21 77.5 0.0 1.5e-20 73.7 0.0 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC33595.1 - 3.4e-17 62.8 0.3 2.6e-12 46.8 0.1 3.4 1 1 1 2 2 2 2 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGC33595.1 - 2.2e-14 53.1 0.1 3.1e-07 29.7 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGC33595.1 - 2.3e-12 46.7 0.1 5.8e-08 32.2 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.17 EGC33595.1 - 1.1e-06 27.9 0.0 0.28 10.2 0.0 3.1 3 0 0 3 3 3 3 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC33595.1 - 3.4e-06 26.4 0.0 0.0064 15.7 0.1 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein AMP-binding PF00501.28 EGC33597.1 - 3.1e-61 207.2 0.0 3.7e-61 207.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC33597.1 - 3.2e-10 39.8 4.8 1e-09 38.1 4.8 2.0 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus CHU_C PF13585.6 EGC33597.1 - 3.7 7.7 7.6 0.21 11.7 0.7 2.5 2 0 0 2 2 2 0 C-terminal domain of CHU protein family V_ATPase_I PF01496.19 EGC33598.1 - 4.7e-295 980.7 8.3 1.4e-294 979.2 8.3 1.6 1 1 0 1 1 1 1 V-type ATPase 116kDa subunit family FTA4 PF13093.6 EGC33598.1 - 0.0046 16.9 3.9 0.0081 16.1 3.9 1.3 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 GAS PF13851.6 EGC33598.1 - 1.2 8.5 12.4 0.36 10.1 8.0 2.0 2 0 0 2 2 2 0 Growth-arrest specific micro-tubule binding FlaC_arch PF05377.11 EGC33598.1 - 1.2 9.6 4.2 1 9.8 1.5 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Occludin_ELL PF07303.13 EGC33598.1 - 1.7 9.4 5.7 14 6.5 0.8 3.1 3 0 0 3 3 3 0 Occludin homology domain zf-CpG_bind_C PF12269.8 EGC33599.1 - 0.72 9.6 4.8 0.46 10.2 1.8 1.7 1 1 1 2 2 2 0 CpG binding protein zinc finger C terminal domain OSTbeta PF15048.6 EGC33599.1 - 4.9 7.3 6.0 17 5.6 6.0 1.8 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein ENTH PF01417.20 EGC33602.1 - 1.6e-43 147.7 0.0 2.5e-43 147.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.16 EGC33602.1 - 0.0083 15.1 0.0 0.014 14.4 0.0 1.4 1 0 0 1 1 1 1 ANTH domain F-box-like PF12937.7 EGC33603.1 - 1e-12 47.7 0.3 1.8e-12 46.9 0.3 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC33603.1 - 8.5e-11 41.5 0.1 1.8e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGC33603.1 - 0.00098 19.0 0.2 0.0027 17.6 0.0 1.8 2 0 0 2 2 2 1 F-box Elongin_A PF06881.11 EGC33603.1 - 0.39 11.3 0.0 0.39 11.3 0.0 3.0 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Orf78 PF06024.12 EGC33606.1 - 0.11 12.8 2.7 0.2 11.9 0.1 2.4 2 1 0 2 2 2 0 Orf78 (ac78) DUF3198 PF11433.8 EGC33606.1 - 0.16 11.9 1.4 1.5 8.8 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3198) Podoplanin PF05808.11 EGC33606.1 - 0.16 12.0 0.0 0.3 11.2 0.0 1.3 1 0 0 1 1 1 0 Podoplanin EGF_2 PF07974.13 EGC33606.1 - 0.63 10.5 7.6 2 8.8 7.6 1.9 1 1 0 1 1 1 0 EGF-like domain Spt20 PF12090.8 EGC33607.1 - 0.0017 18.0 21.2 0.0021 17.7 21.2 1.3 1 0 0 1 1 1 1 Spt20 family FemAB PF02388.16 EGC33607.1 - 0.0031 16.4 7.0 0.0034 16.3 7.0 1.2 1 0 0 1 1 1 1 FemAB family DDHD PF02862.17 EGC33607.1 - 0.0032 17.7 3.8 0.0035 17.5 3.8 1.1 1 0 0 1 1 1 1 DDHD domain AMA-1 PF02430.15 EGC33607.1 - 0.0086 15.1 10.9 0.011 14.7 10.9 1.0 1 0 0 1 1 1 1 Apical membrane antigen 1 DUF4834 PF16118.5 EGC33607.1 - 0.0091 16.9 12.3 0.016 16.1 12.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) OATP PF03137.20 EGC33607.1 - 0.014 13.7 3.3 0.018 13.4 3.3 1.1 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EFTUD2 PF16004.5 EGC33607.1 - 0.018 15.6 12.1 0.023 15.3 12.1 1.2 1 0 0 1 1 1 0 116 kDa U5 small nuclear ribonucleoprotein component N-terminus SLC12 PF03522.15 EGC33607.1 - 0.031 13.3 7.9 0.033 13.2 7.9 1.1 1 0 0 1 1 1 0 Solute carrier family 12 EVI2A PF05399.11 EGC33607.1 - 0.044 13.4 8.6 0.058 13.0 8.6 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Tim54 PF11711.8 EGC33607.1 - 0.047 12.5 9.5 0.056 12.2 9.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Presenilin PF01080.17 EGC33607.1 - 0.05 12.4 8.4 0.055 12.2 8.4 1.1 1 0 0 1 1 1 0 Presenilin Nucleoside_tran PF01733.18 EGC33607.1 - 0.056 12.8 3.1 0.072 12.5 3.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter SID-1_RNA_chan PF13965.6 EGC33607.1 - 0.062 11.7 6.8 0.067 11.6 6.8 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 TERB2 PF15101.6 EGC33607.1 - 0.067 13.2 7.6 0.08 13.0 7.6 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Mem_trans PF03547.18 EGC33607.1 - 0.08 11.3 2.6 0.082 11.3 2.6 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF1676 PF07898.13 EGC33607.1 - 0.082 12.9 9.8 0.14 12.2 9.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1676) PRC2_HTH_1 PF18118.1 EGC33607.1 - 0.092 13.6 6.9 0.16 12.8 6.9 1.4 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain RP-C_C PF11800.8 EGC33607.1 - 0.11 12.6 7.6 0.13 12.3 7.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region TT_ORF1 PF02956.14 EGC33607.1 - 0.11 11.1 11.6 0.13 11.0 11.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 Zip PF02535.22 EGC33607.1 - 0.12 11.6 1.3 0.11 11.6 1.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Apc15p PF05841.11 EGC33607.1 - 0.16 12.8 17.2 0.21 12.4 17.2 1.2 1 0 0 1 1 1 0 Apc15p protein FAM176 PF14851.6 EGC33607.1 - 0.19 11.4 3.7 0.27 10.9 3.7 1.3 1 0 0 1 1 1 0 FAM176 family TMEM51 PF15345.6 EGC33607.1 - 0.2 11.5 6.8 0.23 11.3 6.8 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 AAR2 PF05282.11 EGC33607.1 - 0.27 10.6 8.1 0.35 10.2 8.1 1.1 1 0 0 1 1 1 0 AAR2 protein MPM1 PF17234.2 EGC33607.1 - 0.29 11.4 15.9 0.39 11.0 15.9 1.1 1 0 0 1 1 1 0 Mitochondrial peculiar membrane protein 1 Connexin PF00029.19 EGC33607.1 - 0.3 10.8 5.3 0.35 10.6 5.3 1.1 1 0 0 1 1 1 0 Connexin G0-G1_switch_2 PF15103.6 EGC33607.1 - 0.31 11.5 1.9 1.7 9.1 1.4 2.1 2 0 0 2 2 2 0 G0/G1 switch protein 2 Band_3_cyto PF07565.13 EGC33607.1 - 0.31 10.8 4.8 0.35 10.6 4.8 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4175 PF13779.6 EGC33607.1 - 0.34 8.8 15.0 1.6 6.6 15.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) DUF3464 PF11947.8 EGC33607.1 - 0.54 10.0 13.7 0.9 9.3 13.7 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Sec62 PF03839.16 EGC33607.1 - 0.55 9.7 6.8 0.75 9.3 6.8 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 EIIBC-GUT_N PF03612.14 EGC33607.1 - 0.57 9.9 6.6 0.86 9.3 6.6 1.2 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Menin PF05053.13 EGC33607.1 - 0.73 8.1 9.1 0.84 7.9 9.1 1.1 1 0 0 1 1 1 0 Menin Serinc PF03348.15 EGC33607.1 - 0.74 8.7 4.9 0.87 8.4 4.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) NST1 PF13945.6 EGC33607.1 - 0.95 9.5 23.4 1.3 9.1 23.4 1.2 1 0 0 1 1 1 0 Salt tolerance down-regulator CSG2 PF16965.5 EGC33607.1 - 1 8.3 8.2 1.3 7.9 8.2 1.1 1 0 0 1 1 1 0 Ceramide synthase regulator Neur_chan_memb PF02932.16 EGC33607.1 - 1.3 9.0 5.9 1.5 8.8 5.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PDDEXK_6 PF04720.12 EGC33607.1 - 1.5 8.7 9.4 2 8.3 9.4 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function DUF4820 PF16091.5 EGC33607.1 - 1.9 7.8 11.8 0.34 10.3 8.5 1.4 2 0 0 2 2 1 0 Domain of unknown function (DUF4820) Peroxin-13_N PF04088.13 EGC33607.1 - 2 8.7 6.0 2.5 8.4 5.2 1.6 2 0 0 2 2 1 0 Peroxin 13, N-terminal region Gti1_Pac2 PF09729.9 EGC33607.1 - 3.2 7.8 13.5 4.2 7.4 13.5 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family ALMT PF11744.8 EGC33607.1 - 4.9 5.9 11.6 5.8 5.6 11.6 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 EGC33607.1 - 5.6 6.3 13.7 7.4 5.9 13.7 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT HCO3_cotransp PF00955.21 EGC33607.1 - 7.8 5.2 8.0 9.1 5.0 8.0 1.1 1 0 0 1 1 1 0 HCO3- transporter family DUF4637 PF15470.6 EGC33607.1 - 8.9 6.0 9.7 14 5.4 9.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) Pro_isomerase PF00160.21 EGC33608.1 - 3.9e-49 167.0 0.0 4.4e-49 166.8 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Actin PF00022.19 EGC33609.1 - 1.8e-53 181.6 0.0 2.5e-30 105.4 0.0 2.5 1 1 1 2 2 2 2 Actin Nexin_C PF08628.12 EGC33609.1 - 0.031 14.9 0.1 0.17 12.5 0.0 2.4 2 1 0 2 2 2 0 Sorting nexin C terminal CLASP_N PF12348.8 EGC33610.1 - 8.7e-35 120.3 3.2 1e-34 120.1 3.2 1.0 1 0 0 1 1 1 1 CLASP N terminal DUF4441 PF14536.6 EGC33610.1 - 0.038 14.2 2.5 0.16 12.2 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) FNIP PF05725.12 EGC33611.1 - 8.7e-118 384.3 39.7 3.5e-15 55.9 0.1 9.1 7 1 1 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.13 EGC33611.1 - 8.1e-05 23.0 1.4 17 5.8 0.0 6.9 3 3 7 10 10 10 2 Phage minor tail protein HTH_ABP1_N PF18107.1 EGC33611.1 - 0.076 12.7 0.0 61 3.4 0.0 4.9 6 0 0 6 6 6 0 Fission yeast centromere protein N-terminal domain BTB PF00651.31 EGC33612.1 - 0.0036 17.5 0.8 0.031 14.5 0.1 3.0 3 0 0 3 3 3 1 BTB/POZ domain TFIIA PF03153.13 EGC33612.1 - 0.0095 16.0 3.9 0.0095 16.0 3.9 2.3 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Rap_GAP PF02145.15 EGC33613.1 - 6.7e-61 205.1 0.1 6.7e-61 205.1 0.1 2.0 2 0 0 2 2 2 1 Rap/ran-GAP CNH PF00780.22 EGC33613.1 - 1e-34 120.4 0.3 1.2e-33 116.9 0.3 2.1 1 1 0 1 1 1 1 CNH domain RNA_pol_Rpb5_C PF01191.19 EGC33614.1 - 7.3e-33 112.3 0.1 1.5e-32 111.2 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.14 EGC33614.1 - 5.1e-16 59.0 1.4 4e-14 52.9 0.3 3.0 1 1 1 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Mrr_cat PF04471.12 EGC33614.1 - 0.025 14.6 0.3 0.042 13.9 0.3 1.5 1 1 0 1 1 1 0 Restriction endonuclease POTRA_2 PF08479.11 EGC33614.1 - 0.052 13.4 0.1 0.16 11.8 0.0 1.9 2 0 0 2 2 2 0 POTRA domain, ShlB-type Sof1 PF04158.14 EGC33614.1 - 0.095 13.0 0.5 0.22 11.8 0.2 1.8 2 0 0 2 2 2 0 Sof1-like domain Copine PF07002.16 EGC33615.1 - 1.8e-57 194.3 0.0 2.6e-57 193.8 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC33615.1 - 9.1e-22 77.3 0.7 1.2e-11 44.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC33615.1 - 0.00042 20.5 0.0 0.0012 19.0 0.0 1.8 1 1 0 1 1 1 1 vWA found in TerF C terminus Frizzled PF01534.17 EGC33616.1 - 4.5e-07 29.2 21.6 6.9e-07 28.6 21.6 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region Fz PF01392.22 EGC33616.1 - 0.011 16.3 2.4 0.023 15.3 2.4 1.5 1 0 0 1 1 1 0 Fz domain zf-LITAF-like PF10601.9 EGC33616.1 - 5.7 7.3 11.1 2 8.8 0.0 4.2 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain zf-C3HC4_3 PF13920.6 EGC33617.1 - 3.4e-07 30.0 9.8 5.9e-07 29.2 9.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC33617.1 - 4.9e-07 30.0 13.2 1.2e-06 28.8 13.2 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33617.1 - 1.4e-05 24.8 11.8 2.6e-05 24.0 11.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33617.1 - 2.4e-05 24.1 13.5 4.9e-05 23.1 13.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC33617.1 - 0.013 15.2 7.1 0.032 14.0 7.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EGC33617.1 - 0.018 14.8 11.9 0.035 13.9 11.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC33617.1 - 0.025 14.8 11.3 0.025 14.8 11.3 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC33617.1 - 0.12 12.5 9.8 0.27 11.3 9.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGC33617.1 - 0.26 11.3 13.8 0.32 11.0 12.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC33617.1 - 0.74 10.0 12.9 1.8 8.8 12.9 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DNTTIP1_dimer PF18192.1 EGC33618.1 - 3.9 7.9 5.7 1.4 9.3 0.4 2.6 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain HA2 PF04408.23 EGC33619.1 - 6.4e-23 81.1 0.0 2.2e-22 79.4 0.0 2.0 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC33619.1 - 5.2e-17 62.0 0.0 1.3e-16 60.8 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.29 EGC33619.1 - 0.026 14.3 0.1 0.24 11.2 0.1 2.2 1 1 0 1 1 1 0 DEAD/DEAH box helicase AAA_23 PF13476.6 EGC33619.1 - 9.7 6.6 11.2 0.85 10.1 0.1 2.6 2 1 1 3 3 3 0 AAA domain Pkinase PF00069.25 EGC33620.1 - 2e-37 129.0 0.2 6e-37 127.4 0.2 1.9 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33620.1 - 1.1e-26 93.7 0.0 2.2e-26 92.7 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGC33620.1 - 7.9e-14 51.9 5.7 1.5e-13 51.0 3.8 2.6 2 0 0 2 2 2 1 Ribonuclease 2-5A Kdo PF06293.14 EGC33620.1 - 0.014 14.7 0.0 0.029 13.7 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ras PF00071.22 EGC33622.1 - 6.9e-23 81.0 0.0 1e-22 80.4 0.0 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33622.1 - 7.3e-08 32.7 0.0 1.3e-07 31.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC33623.1 - 1.1e-24 86.8 0.6 1.9e-24 86.1 0.6 1.3 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC33623.1 - 9.6e-10 38.7 0.8 3.3e-09 37.0 0.0 2.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC33624.1 - 1.7e-24 86.2 0.2 2.2e-24 85.9 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33624.1 - 3.5e-08 33.7 0.2 8e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC33624.1 - 0.0029 17.0 0.1 0.0083 15.6 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGC33624.1 - 0.014 14.8 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family Pkinase PF00069.25 EGC33625.1 - 1.6e-58 198.1 0.0 2.6e-58 197.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33625.1 - 2e-44 151.8 0.0 3.1e-44 151.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_2 PF07653.17 EGC33625.1 - 2.9e-07 30.1 0.0 5.6e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.6 EGC33625.1 - 6.7e-07 29.1 0.0 1.2e-06 28.3 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC33625.1 - 4.4e-06 26.2 0.0 8e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Pkinase_fungal PF17667.1 EGC33625.1 - 3.4e-05 22.8 0.0 3.4e-05 22.8 0.0 2.6 2 1 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGC33625.1 - 0.0011 18.4 0.0 0.0029 17.0 0.0 1.7 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGC33625.1 - 0.0038 17.2 0.0 0.0074 16.2 0.0 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC33625.1 - 0.011 14.8 0.0 0.023 13.7 0.0 1.4 1 0 0 1 1 1 0 Seadornavirus VP7 Macoilin PF09726.9 EGC33625.1 - 4 5.9 16.6 5.8 5.3 16.6 1.2 1 0 0 1 1 1 0 Macoilin family CBM49 PF09478.10 EGC33626.1 - 2.2e-32 111.2 9.6 7.5e-22 77.4 1.2 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 PARM PF17061.5 EGC33626.1 - 0.002 18.4 44.7 0.0065 16.6 7.5 2.2 2 0 0 2 2 2 2 PARM Erf4 PF10256.9 EGC33628.1 - 0.00019 21.5 0.5 0.00019 21.5 0.5 2.0 2 0 0 2 2 1 1 Golgin subfamily A member 7/ERF4 family DUF5523 PF17661.1 EGC33628.1 - 0.045 13.4 6.1 0.06 13.0 6.1 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5523) Tuberin PF03542.16 EGC33628.1 - 0.11 11.6 7.3 0.14 11.3 7.3 1.1 1 0 0 1 1 1 0 Tuberin AAR2 PF05282.11 EGC33628.1 - 0.17 11.2 4.7 0.22 10.9 4.7 1.1 1 0 0 1 1 1 0 AAR2 protein DUF1512 PF07431.12 EGC33628.1 - 0.2 10.6 4.0 0.24 10.4 4.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1512) DUF4119 PF13494.6 EGC33628.1 - 0.35 11.0 3.2 0.64 10.2 2.9 1.7 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) POX PF07526.11 EGC33628.1 - 1.3 9.6 4.8 2.1 8.9 4.8 1.3 1 0 0 1 1 1 0 Associated with HOX Menin PF05053.13 EGC33628.1 - 1.6 7.0 11.9 1.9 6.8 11.9 1.1 1 0 0 1 1 1 0 Menin TMEM51 PF15345.6 EGC33628.1 - 1.9 8.3 8.2 7.4 6.3 0.3 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 DUF3276 PF11680.8 EGC33628.1 - 3.4 7.8 14.9 14 5.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3276) DUF4820 PF16091.5 EGC33628.1 - 6.6 6.0 9.4 9.9 5.5 9.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) DUF4834 PF16118.5 EGC33629.1 - 0.11 13.5 7.7 22 6.1 7.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) DUF853 PF05872.12 EGC33629.1 - 0.43 9.1 2.2 0.58 8.7 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) CPSF100_C PF13299.6 EGC33629.1 - 8.6 6.5 12.6 0.99 9.6 4.9 2.1 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Nucleoside_tran PF01733.18 EGC33630.1 - 2.9e-36 125.4 17.4 2.9e-36 125.4 17.4 1.8 2 0 0 2 2 2 1 Nucleoside transporter FNIP PF05725.12 EGC33632.1 - 1.6e-173 562.7 66.5 2.9e-15 56.2 1.3 14.5 9 3 3 14 14 14 14 FNIP Repeat zf-RING_2 PF13639.6 EGC33633.1 - 1.5e-09 38.1 9.2 2.6e-09 37.3 9.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC33633.1 - 2e-08 34.0 6.8 3.3e-08 33.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC33633.1 - 9.8e-08 31.7 7.6 1.8e-07 30.9 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33633.1 - 7.1e-07 29.0 10.0 1.4e-06 28.1 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33633.1 - 3.6e-06 27.1 5.0 1.2e-05 25.5 5.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC33633.1 - 0.00011 22.2 3.9 0.00022 21.2 3.9 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC33633.1 - 0.00026 20.9 9.1 0.00052 19.9 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC33633.1 - 0.0024 17.7 5.5 0.0051 16.7 5.5 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC33633.1 - 0.0028 17.4 6.5 0.0057 16.4 6.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC33633.1 - 0.0043 16.8 9.8 0.0079 16.0 9.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC33633.1 - 0.0068 16.4 1.0 0.017 15.2 1.0 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Hamartin PF04388.12 EGC33633.1 - 0.016 13.9 27.3 0.022 13.4 27.3 1.2 1 0 0 1 1 1 0 Hamartin protein zf-C3HC4_4 PF15227.6 EGC33633.1 - 0.024 14.8 10.1 0.066 13.4 10.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.11 EGC33633.1 - 0.031 14.2 2.5 0.044 13.7 0.9 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.6 EGC33633.1 - 0.6 10.0 3.4 1.4 8.9 3.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 EGC33633.1 - 0.83 9.8 6.4 1.9 8.6 6.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 EGC33633.1 - 1.8 8.6 7.3 0.96 9.5 4.6 1.9 2 0 0 2 2 1 0 Double zinc ribbon zf-LITAF-like PF10601.9 EGC33634.1 - 0.072 13.4 0.0 0.1 12.9 0.0 1.2 1 0 0 1 1 1 0 LITAF-like zinc ribbon domain FH2 PF02181.23 EGC33637.1 - 4.4e-78 263.0 0.4 4.4e-78 263.0 0.4 3.4 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EGC33637.1 - 2.5e-29 102.3 3.4 2.5e-29 102.3 3.4 3.1 4 0 0 4 4 4 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EGC33637.1 - 1.2e-13 51.1 1.2 1.2e-13 51.1 1.2 3.7 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain C1_1 PF00130.22 EGC33637.1 - 0.00044 20.1 9.4 0.00091 19.1 9.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) SDA1 PF05285.12 EGC33637.1 - 0.00052 19.6 34.4 0.00078 19.0 25.8 2.5 2 0 0 2 2 2 2 SDA1 Caldesmon PF02029.15 EGC33637.1 - 0.0031 16.3 23.1 0.0031 16.3 23.1 2.4 2 0 0 2 2 2 1 Caldesmon Fe_bilin_red PF05996.12 EGC33637.1 - 0.0059 16.3 1.6 0.014 15.1 1.6 1.6 1 0 0 1 1 1 1 Ferredoxin-dependent bilin reductase Zf_RING PF16744.5 EGC33637.1 - 0.018 15.1 3.3 0.064 13.4 3.3 1.9 1 0 0 1 1 1 0 KIAA1045 RING finger C1_2 PF03107.16 EGC33637.1 - 0.6 10.5 7.6 1.2 9.5 7.6 1.5 1 0 0 1 1 1 0 C1 domain Borrelia_P83 PF05262.11 EGC33637.1 - 5.5 5.4 30.0 1.1 7.7 19.7 2.4 2 0 0 2 2 2 0 Borrelia P83/100 protein RhoGAP PF00620.27 EGC33638.1 - 1.1e-28 99.9 0.1 1e-27 96.8 0.0 2.6 2 0 0 2 2 2 1 RhoGAP domain KaiA PF07688.12 EGC33638.1 - 0.031 14.4 0.6 0.2 11.8 0.1 2.6 2 0 0 2 2 2 0 KaiA C-terminal domain RasGEF PF00617.19 EGC33639.1 - 3.3e-56 190.3 1.3 8.4e-56 189.0 1.3 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGC33639.1 - 1.9e-20 73.1 2.4 1.9e-20 73.1 2.4 3.3 3 1 0 3 3 3 1 RasGEF N-terminal motif FERM_f0 PF16511.5 EGC33639.1 - 5.1e-11 42.7 0.6 1.2e-05 25.5 0.0 3.6 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM FERM_N PF09379.10 EGC33639.1 - 0.0043 17.0 0.3 8.8 6.4 0.0 4.2 4 1 0 4 4 4 2 FERM N-terminal domain AUX_IAA PF02309.16 EGC33639.1 - 0.22 11.4 0.5 3.1 7.6 0.1 2.5 2 0 0 2 2 2 0 AUX/IAA family AnmK PF03702.14 EGC33640.1 - 3.7e-138 460.6 0.0 4.2e-138 460.4 0.0 1.0 1 0 0 1 1 1 1 Anhydro-N-acetylmuramic acid kinase FGGY_C PF02782.16 EGC33640.1 - 0.06 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain PA28_beta PF02252.18 EGC33641.1 - 3.6e-49 166.2 2.4 5.7e-49 165.5 2.4 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.18 EGC33641.1 - 0.0043 17.0 0.5 0.014 15.4 0.2 2.0 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit DUF5618 PF18498.1 EGC33641.1 - 0.039 14.1 0.7 0.039 14.1 0.7 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF5618) SNF2_N PF00176.23 EGC33642.1 - 2.2e-58 197.6 0.3 3.9e-58 196.8 0.3 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC33642.1 - 1.7e-16 60.5 0.5 1.5e-15 57.5 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC33642.1 - 1.3e-09 38.3 0.2 1.3e-09 38.3 0.2 2.9 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC33642.1 - 4.7e-07 29.7 1.0 8.7e-07 28.9 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase DTHCT PF08070.11 EGC33642.1 - 1.8 9.3 16.8 0.086 13.6 10.8 2.0 2 0 0 2 2 2 0 DTHCT (NUC029) region CENP-Q PF13094.6 EGC33642.1 - 7.7 6.7 21.5 0.75 10.0 0.5 2.9 3 0 0 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit EGF_2 PF07974.13 EGC33643.1 - 4.4e-05 23.8 27.7 0.005 17.2 13.2 2.7 2 0 0 2 2 2 2 EGF-like domain TIG PF01833.24 EGC33643.1 - 0.00063 19.8 0.2 0.00063 19.8 0.2 5.2 5 0 0 5 5 5 1 IPT/TIG domain SHOCT PF09851.9 EGC33644.1 - 3.5e-07 29.8 0.1 5.6e-07 29.1 0.1 1.4 1 0 0 1 1 1 1 Short C-terminal domain DUF3760 PF12586.8 EGC33644.1 - 0.74 10.0 5.0 66 3.8 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3760) Orthopox_F7 PF05813.12 EGC33644.1 - 6.4 7.0 10.4 0.73 10.0 2.4 2.4 2 0 0 2 2 2 0 Orthopoxvirus F7 protein TFIIS_C PF01096.18 EGC33646.1 - 4.7e-18 64.8 2.3 4.7e-18 64.8 2.3 2.6 2 1 0 2 2 1 1 Transcription factor S-II (TFIIS) DUF523 PF04463.12 EGC33646.1 - 1.9e-07 31.2 0.5 2.3e-07 30.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) Ogr_Delta PF04606.12 EGC33646.1 - 0.019 14.9 1.9 0.019 14.9 1.9 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger DZR PF12773.7 EGC33646.1 - 0.028 14.4 12.4 0.089 12.8 1.9 3.0 2 1 1 3 3 3 0 Double zinc ribbon Zn_Tnp_IS1595 PF12760.7 EGC33646.1 - 0.037 14.0 0.7 0.037 14.0 0.7 2.4 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Baculo_LEF5_C PF11792.8 EGC33646.1 - 0.072 12.8 1.2 0.072 12.8 1.2 2.5 3 1 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain zf-RING_7 PF02591.15 EGC33646.1 - 0.11 12.7 5.0 3.4 8.0 0.3 3.1 3 0 0 3 3 3 0 C4-type zinc ribbon domain MqsA_antitoxin PF15731.5 EGC33646.1 - 0.13 12.3 2.4 5.8 7.0 0.4 2.2 2 0 0 2 2 2 0 Antitoxin component of bacterial toxin-antitoxin system, MqsA DNA_RNApol_7kD PF03604.13 EGC33646.1 - 0.29 10.8 6.2 3.9 7.2 0.1 3.5 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit IBR PF01485.21 EGC33646.1 - 0.32 11.3 11.1 1.5 9.1 0.6 2.6 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain TF_Zn_Ribbon PF08271.12 EGC33646.1 - 0.36 10.4 7.6 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 TFIIB zinc-binding zf-ribbon_3 PF13248.6 EGC33646.1 - 0.65 9.5 13.3 0.54 9.7 1.0 3.3 4 0 0 4 4 4 0 zinc-ribbon domain C1_4 PF07975.12 EGC33646.1 - 0.66 10.3 14.2 4.9 7.5 2.9 3.3 1 1 3 4 4 4 0 TFIIH C1-like domain zf-C4_Topoisom PF01396.19 EGC33646.1 - 0.75 9.6 10.9 0.79 9.6 2.5 3.0 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger RNA_POL_M_15KD PF02150.16 EGC33646.1 - 0.83 9.6 12.8 1.4 8.9 2.5 3.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit Ribosomal_S27e PF01667.17 EGC33646.1 - 0.99 9.2 9.7 0.38 10.5 1.5 3.0 2 1 0 2 2 2 0 Ribosomal protein S27 DUF3268 PF11672.8 EGC33646.1 - 1.1 9.6 6.5 1.9 8.8 0.9 2.3 2 1 0 2 2 2 0 zinc-finger-containing domain Lar_restr_allev PF14354.6 EGC33646.1 - 1.3 9.4 7.9 2.5 8.5 1.2 2.5 2 1 0 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_9 PF14369.6 EGC33646.1 - 1.6 9.1 10.4 7.6 6.9 2.3 3.1 3 0 0 3 3 3 0 zinc-ribbon zinc_ribbon_2 PF13240.6 EGC33646.1 - 2.9 7.7 16.4 1.6 8.5 1.2 3.2 3 0 0 3 3 3 0 zinc-ribbon domain PADR1 PF08063.12 EGC33646.1 - 3.6 7.4 13.6 2.1 8.2 4.1 3.4 2 2 1 3 3 3 0 PADR1 (NUC008) domain zinc_ribbon_4 PF13717.6 EGC33646.1 - 4.1 7.4 15.4 11 6.1 0.1 4.6 4 1 0 4 4 4 0 zinc-ribbon domain UPF0547 PF10571.9 EGC33646.1 - 4.2 7.5 11.6 16 5.7 1.2 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 Zn_Tnp_IS91 PF14319.6 EGC33646.1 - 6.1 7.0 12.9 1.8 8.6 1.2 3.0 1 1 0 2 2 2 0 Transposase zinc-binding domain PhnA_Zn_Ribbon PF08274.12 EGC33646.1 - 6.1 6.9 9.6 4.5 7.3 0.3 3.0 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Hexapep PF00132.24 EGC33647.1 - 0.0002 21.0 18.9 0.00082 19.0 2.4 4.7 2 2 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Phosducin PF02114.16 EGC33648.1 - 9e-16 57.6 1.5 9e-16 57.6 1.5 1.4 1 1 0 1 1 1 1 Phosducin Thioredoxin PF00085.20 EGC33648.1 - 0.0065 16.4 0.0 0.022 14.7 0.0 1.9 1 1 0 1 1 1 1 Thioredoxin RtcB PF01139.17 EGC33648.1 - 0.063 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PepSY_TM PF03929.16 EGC33649.1 - 6e-07 29.4 14.1 0.00031 20.5 2.2 3.1 1 1 2 3 3 3 3 PepSY-associated TM region RSN1_7TM PF02714.15 EGC33649.1 - 0.00027 20.3 3.3 0.00027 20.3 3.3 1.7 2 0 0 2 2 2 1 Calcium-dependent channel, 7TM region, putative phosphate DUF4079 PF13301.6 EGC33649.1 - 0.017 15.2 4.4 0.46 10.6 4.1 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF4079) Ni_hydr_CYTB PF01292.20 EGC33649.1 - 0.18 11.4 10.3 0.066 12.8 4.8 2.4 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 DUF4271 PF14093.6 EGC33649.1 - 0.23 11.4 7.1 0.25 11.2 3.6 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) SR-25 PF10500.9 EGC33650.1 - 3.3 7.3 7.4 6.6 6.3 7.4 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FNIP PF05725.12 EGC33653.1 - 2.4e-27 94.8 29.0 5.3e-11 42.5 0.5 6.2 4 1 2 6 6 6 4 FNIP Repeat YXWGXW PF12779.7 EGC33654.1 - 2.7 8.2 4.5 1.4 9.2 1.8 1.8 2 0 0 2 2 2 0 YXWGXW repeat (2 copies) F-box-like PF12937.7 EGC33655.1 - 1.1e-06 28.4 0.4 6.7e-06 25.9 0.1 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGC33655.1 - 0.00016 21.5 0.0 0.00036 20.3 0.0 1.5 1 0 0 1 1 1 1 F-box domain Presenilin PF01080.17 EGC33655.1 - 0.0042 15.9 3.5 0.0042 15.9 3.5 1.8 2 0 0 2 2 2 1 Presenilin SID-1_RNA_chan PF13965.6 EGC33655.1 - 0.4 9.0 4.7 0.64 8.4 4.7 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neur_chan_memb PF02932.16 EGC33655.1 - 5.5 7.0 8.4 7 6.6 5.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Metallophos PF00149.28 EGC33656.1 - 4.4e-16 60.0 3.4 1.4e-15 58.3 3.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC33656.1 - 3.2e-07 30.7 0.0 5.5e-07 29.9 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ROK PF00480.20 EGC33656.1 - 0.08 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 ROK family Oxidored_q3 PF00499.20 EGC33657.1 - 0.0069 16.1 8.8 0.0079 15.9 6.5 1.9 2 0 0 2 2 2 1 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Claudin_2 PF13903.6 EGC33657.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Pox_P21 PF05313.12 EGC33657.1 - 0.18 11.4 4.0 0.043 13.4 1.0 1.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein ArfGap PF01412.18 EGC33658.1 - 2.8e-26 91.9 4.9 2.8e-26 91.9 4.9 3.4 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SH3_9 PF14604.6 EGC33658.1 - 9.4e-13 47.8 0.0 2e-12 46.8 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC33658.1 - 2.3e-09 36.7 0.1 5.5e-09 35.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGC33658.1 - 4e-05 23.2 0.0 8.3e-05 22.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain BCL_N PF04714.13 EGC33658.1 - 0.015 15.4 0.2 0.6 10.2 0.1 2.8 2 0 0 2 2 2 0 BCL7, N-terminal conserver region RBD PF02196.15 EGC33658.1 - 0.046 13.8 0.0 0.11 12.6 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain PB1 PF00564.24 EGC33658.1 - 0.084 12.8 0.2 0.61 10.1 0.0 2.4 2 0 0 2 2 2 0 PB1 domain Kelch_3 PF13415.6 EGC33658.1 - 0.15 12.4 0.2 2.1 8.7 0.0 2.7 2 0 0 2 2 2 0 Galactose oxidase, central domain MFS_1 PF07690.16 EGC33659.1 - 8.7e-46 156.4 43.7 1.4e-37 129.5 28.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC33659.1 - 0.0014 17.6 37.9 0.1 11.5 38.0 2.3 1 1 0 1 1 1 1 Sugar (and other) transporter IF-2B PF01008.17 EGC33660.1 - 1.9e-81 273.4 0.2 2.3e-81 273.1 0.2 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PUF PF00806.19 EGC33660.1 - 0.073 12.8 0.1 0.28 10.9 0.1 2.1 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Usp PF00582.26 EGC33661.1 - 1.7e-14 54.5 0.0 2.1e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family MGS PF02142.22 EGC33661.1 - 0.0049 17.0 0.1 0.0073 16.5 0.1 1.3 1 1 0 1 1 1 1 MGS-like domain DUF5062 PF16691.5 EGC33661.1 - 0.026 14.6 0.0 0.056 13.6 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5062) Hus1 PF04005.12 EGC33662.1 - 3.8e-70 236.3 6.3 5.2e-70 235.9 6.3 1.2 1 0 0 1 1 1 1 Hus1-like protein Redoxin PF08534.10 EGC33663.1 - 3.9e-30 104.5 0.0 4.4e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.21 EGC33663.1 - 9e-08 32.1 0.0 1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FKBP_C PF00254.28 EGC33664.1 - 6.2e-27 93.8 0.2 9.4e-27 93.2 0.2 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2232 PF09991.9 EGC33664.1 - 0.074 12.2 0.7 0.27 10.4 0.1 1.8 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) LPAM_1 PF08139.12 EGC33664.1 - 5.8 7.6 5.4 1.2 9.8 0.9 2.1 2 0 0 2 2 2 0 Prokaryotic membrane lipoprotein lipid attachment site PA14 PF07691.12 EGC33665.1 - 6.6e-09 35.7 0.4 1.2e-08 34.9 0.0 1.6 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.18 EGC33665.1 - 3.2e-07 30.1 16.1 4.2e-07 29.8 6.2 8.9 8 2 1 9 9 9 4 Dictyostelium (slime mold) repeat DUF4692 PF15763.5 EGC33665.1 - 0.9 10.0 3.6 1.7 9.1 3.6 1.4 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) Chlam_PMP PF02415.17 EGC33666.1 - 0.14 12.7 44.5 2.2 8.9 0.9 8.5 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Jnk-SapK_ap_N PF09744.9 EGC33670.1 - 0.0063 16.7 45.4 0.092 13.0 26.2 3.1 1 1 2 3 3 3 2 JNK_SAPK-associated protein-1 CLZ PF16526.5 EGC33670.1 - 0.013 15.8 11.1 0.013 15.8 11.1 2.6 1 1 1 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels GyrB_insert PF18053.1 EGC33670.1 - 0.27 11.1 12.6 0.1 12.5 9.9 1.6 1 1 0 1 1 1 0 DNA gyrase B subunit insert domain Seryl_tRNA_N PF02403.22 EGC33670.1 - 0.52 10.6 40.1 0.36 11.1 18.1 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Exonuc_VII_L PF02601.15 EGC33670.1 - 0.91 9.0 21.9 1.6 8.2 21.9 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF1241 PF06840.11 EGC33670.1 - 1.7 8.3 20.1 0.094 12.4 9.1 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1241) LMBR1 PF04791.16 EGC33670.1 - 1.9 7.3 16.8 3 6.6 16.8 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Hemerythrin PF01814.23 EGC33670.1 - 1.9 9.1 7.9 4.2 8.0 2.1 2.4 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Leu_zip PF15294.6 EGC33670.1 - 2.1 7.8 37.6 3.6 7.0 37.6 1.3 1 0 0 1 1 1 0 Leucine zipper THOC7 PF05615.13 EGC33670.1 - 2.9 8.2 36.7 2.7 8.3 15.6 2.6 1 1 1 2 2 2 0 Tho complex subunit 7 DUF4763 PF15960.5 EGC33670.1 - 4.1 6.6 41.1 8.8 5.6 11.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) Mto2_bdg PF12808.7 EGC33670.1 - 5 7.5 24.6 1.5 9.2 1.4 3.6 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region DUF4407 PF14362.6 EGC33670.1 - 6.1 6.1 24.4 11 5.2 24.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 EGC33670.1 - 6.2 7.2 42.5 8 6.9 17.4 3.3 1 1 2 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Cnn_1N PF07989.11 EGC33670.1 - 7.9 6.7 49.2 2 8.7 20.3 3.3 1 1 2 3 3 3 0 Centrosomin N-terminal motif 1 DUF4509 PF14970.6 EGC33670.1 - 8.2 6.3 28.4 1.2 9.1 11.3 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4509) ADIP PF11559.8 EGC33670.1 - 8.9 6.4 47.0 0.26 11.4 17.4 2.5 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Golgin_A5 PF09787.9 EGC33670.1 - 9.1 5.6 41.4 19 4.6 40.6 1.7 1 1 1 2 2 2 0 Golgin subfamily A member 5 SPX PF03105.19 EGC33672.1 - 2.7 7.8 4.2 4.1 7.2 4.2 1.2 1 0 0 1 1 1 0 SPX domain Spem1 PF15670.5 EGC33673.1 - 0.0035 17.0 7.1 0.0074 15.9 7.1 1.5 1 0 0 1 1 1 1 Spermatid maturation protein 1 Neur_chan_memb PF02932.16 EGC33673.1 - 0.11 12.5 0.6 0.13 12.4 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGC33673.1 - 0.36 10.0 5.0 0.51 9.5 5.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 EGC33673.1 - 0.96 9.2 3.5 1.6 8.5 3.5 1.3 1 0 0 1 1 1 0 Connexin IF-2B PF01008.17 EGC33674.1 - 0.83 8.8 4.9 0.45 9.7 0.6 2.3 2 0 0 2 2 2 0 Initiation factor 2 subunit family DUF3915 PF13054.6 EGC33674.1 - 6.1 6.9 9.0 0.31 11.0 1.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) zf-NPL4 PF05020.15 EGC33674.1 - 9.9 6.3 8.0 2.7 8.1 0.3 3.0 3 0 0 3 3 3 0 NPL4 family, putative zinc binding region GTP_EFTU PF00009.27 EGC33675.1 - 4.5e-42 143.8 0.0 6.1e-42 143.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGC33675.1 - 9.4e-25 87.1 0.0 3.1e-24 85.4 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGC33675.1 - 4.6e-06 26.9 1.0 1.3e-05 25.5 0.4 2.1 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC33675.1 - 0.00037 20.6 0.1 0.0032 17.5 0.1 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PAM2 PF07145.15 EGC33675.1 - 0.002 17.7 0.6 0.0072 15.9 0.6 2.1 1 0 0 1 1 1 1 Ataxin-2 C-terminal region AbiJ_NTD3 PF18860.1 EGC33675.1 - 0.0034 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 AbiJ N-terminal domain 3 G-alpha PF00503.20 EGC33675.1 - 0.033 13.4 0.0 0.12 11.5 0.0 1.8 1 1 1 2 2 2 0 G-protein alpha subunit Mitofilin PF09731.9 EGC33675.1 - 0.12 11.2 3.0 0.19 10.6 3.0 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ANTH PF07651.16 EGC33676.1 - 6.9e-52 176.1 0.5 1.3e-51 175.2 0.5 1.5 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.20 EGC33676.1 - 5.1e-05 23.3 0.0 0.00011 22.3 0.0 1.5 1 0 0 1 1 1 1 ENTH domain TERB2 PF15101.6 EGC33677.1 - 3.9 7.5 8.3 4.1 7.4 8.3 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 FKBP_N PF01346.18 EGC33679.1 - 0.022 15.7 4.3 0.025 15.5 4.3 1.1 1 0 0 1 1 1 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase LRS4 PF10422.9 EGC33679.1 - 0.69 9.4 5.3 0.76 9.3 5.3 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 YabA PF06156.13 EGC33680.1 - 0.059 14.0 7.4 1.6 9.4 0.8 2.4 1 1 1 2 2 2 0 Initiation control protein YabA Toxin_trans PF07952.12 EGC33680.1 - 0.094 11.8 7.2 0.064 12.3 5.3 1.7 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain Nop14 PF04147.12 EGC33681.1 - 1.5 6.9 8.2 1.8 6.7 8.2 1.2 1 0 0 1 1 1 0 Nop14-like family DUF2457 PF10446.9 EGC33681.1 - 2.5 7.1 14.7 2.9 6.9 14.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RhoGAP PF00620.27 EGC33682.1 - 1.8e-34 118.7 7.1 5.4e-34 117.2 0.6 4.1 4 0 0 4 4 4 1 RhoGAP domain RhoGEF PF00621.20 EGC33682.1 - 5e-29 101.8 0.5 5e-29 101.8 0.5 3.2 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGC33682.1 - 0.0005 20.5 1.2 0.0031 18.0 1.2 2.5 1 0 0 1 1 1 1 PH domain Abhydrolase_1 PF00561.20 EGC33683.1 - 1.4e-17 64.2 0.0 1.8e-15 57.3 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC33683.1 - 9.7e-14 52.5 0.0 2.4e-13 51.2 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC33683.1 - 3.4e-09 36.3 0.0 4.6e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGC33683.1 - 4.8e-06 26.5 0.5 4.7e-05 23.2 0.5 2.1 1 1 0 1 1 1 1 PGAP1-like protein Ndr PF03096.14 EGC33683.1 - 5.6e-06 25.3 0.0 1.9e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Ndr family Thioesterase PF00975.20 EGC33683.1 - 1.5e-05 25.2 0.0 2.1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.14 EGC33683.1 - 0.00013 21.6 0.5 0.00037 20.1 0.3 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGC33683.1 - 0.0004 20.3 0.2 0.00093 19.1 0.1 1.6 2 0 0 2 2 2 1 Palmitoyl protein thioesterase Lipase_3 PF01764.25 EGC33683.1 - 0.00064 19.6 0.0 0.0011 18.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.20 EGC33683.1 - 0.0026 17.4 0.0 0.0069 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Abhydrolase_5 PF12695.7 EGC33683.1 - 0.018 14.8 0.0 0.065 13.0 0.0 1.9 2 0 0 2 2 2 0 Alpha/beta hydrolase family Chlorophyllase PF07224.11 EGC33683.1 - 0.019 14.0 0.0 0.04 12.9 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase BAAT_C PF08840.11 EGC33683.1 - 0.021 14.7 0.0 0.067 13.1 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.18 EGC33683.1 - 0.025 14.1 0.0 1.3 8.6 0.0 2.2 1 1 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGC33684.1 - 7.2e-24 84.8 0.0 2e-17 63.7 0.0 2.0 2 0 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC33684.1 - 9.2e-16 59.1 0.0 1.2e-15 58.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC33684.1 - 5.4e-12 45.5 0.0 7.8e-11 41.7 0.0 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGC33684.1 - 1.6e-06 28.1 0.1 1e-05 25.4 0.1 2.2 1 1 0 1 1 1 1 PGAP1-like protein DLH PF01738.18 EGC33684.1 - 8.9e-06 25.4 0.0 0.29 10.7 0.0 3.1 3 0 0 3 3 3 2 Dienelactone hydrolase family Thioesterase PF00975.20 EGC33684.1 - 5.9e-05 23.3 0.0 7.8e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain Esterase PF00756.20 EGC33684.1 - 0.00022 20.9 0.0 0.0013 18.5 0.0 1.9 1 1 1 2 2 2 1 Putative esterase Lipase_3 PF01764.25 EGC33684.1 - 0.00093 19.1 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) DUF676 PF05057.14 EGC33684.1 - 0.001 18.7 0.1 0.0015 18.0 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.14 EGC33684.1 - 0.0025 16.6 0.0 0.0045 15.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.11 EGC33684.1 - 0.014 15.3 0.0 0.044 13.7 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DUF915 PF06028.11 EGC33684.1 - 0.016 14.6 0.1 0.12 11.7 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Chlorophyllase PF07224.11 EGC33684.1 - 0.038 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Palm_thioest PF02089.15 EGC33684.1 - 0.075 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Palmitoyl protein thioesterase DUF900 PF05990.12 EGC33684.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Pkinase PF00069.25 EGC33687.1 - 4.4e-54 183.6 0.1 4.4e-54 183.6 0.1 3.0 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33687.1 - 6.8e-29 100.9 0.0 6.8e-29 100.9 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase RIO1 PF01163.22 EGC33687.1 - 0.0013 18.3 0.4 0.0013 18.3 0.4 2.4 2 1 0 2 2 2 1 RIO1 family APH PF01636.23 EGC33687.1 - 0.11 12.4 4.8 0.35 10.8 0.0 2.9 2 1 1 3 3 3 0 Phosphotransferase enzyme family YL1 PF05764.13 EGC33687.1 - 5.9 6.9 45.6 0.36 10.9 37.6 2.5 2 0 0 2 2 2 0 YL1 nuclear protein COPIIcoated_ERV PF07970.12 EGC33688.1 - 8.5e-53 179.5 0.2 1.4e-52 178.8 0.2 1.3 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGC33688.1 - 1.4e-22 79.8 0.2 2.6e-22 78.9 0.2 1.4 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Sin3a_C PF16879.5 EGC33689.1 - 9.6e-67 225.7 9.0 9.6e-67 225.7 9.0 6.7 5 2 2 7 7 7 1 C-terminal domain of Sin3a protein Sin3_corepress PF08295.12 EGC33689.1 - 1.3e-37 127.8 0.0 3.3e-36 123.3 0.0 3.7 2 0 0 2 2 2 1 Sin3 family co-repressor PAH PF02671.21 EGC33689.1 - 3.8e-32 110.2 32.6 4.4e-16 58.7 1.8 6.5 6 0 0 6 6 6 4 Paired amphipathic helix repeat Coiled PF05710.12 EGC33690.1 - 0.016 16.0 5.0 0.019 15.8 5.0 1.1 1 0 0 1 1 1 0 Coiled coil F-box PF00646.33 EGC33692.1 - 0.00081 19.2 0.2 0.0022 17.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGC33692.1 - 0.0026 17.6 0.1 0.0054 16.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like Dehydrin PF00257.19 EGC33692.1 - 0.51 10.9 8.0 0.96 10.0 8.0 1.3 1 0 0 1 1 1 0 Dehydrin V-set PF07686.17 EGC33694.1 - 0.013 15.7 0.0 0.037 14.2 0.0 1.7 1 1 0 1 1 1 0 Immunoglobulin V-set domain FAM176 PF14851.6 EGC33694.1 - 0.058 13.1 0.3 0.086 12.5 0.3 1.3 1 0 0 1 1 1 0 FAM176 family DUF4710 PF15828.5 EGC33694.1 - 0.81 9.9 8.8 1.5 9.0 8.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4710) F-box PF00646.33 EGC33696.1 - 0.00078 19.3 0.2 0.0022 17.8 0.2 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGC33696.1 - 0.0025 17.7 0.1 0.0054 16.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like Dehydrin PF00257.19 EGC33696.1 - 2.9 8.4 7.0 5.3 7.6 7.0 1.3 1 0 0 1 1 1 0 Dehydrin FNIP PF05725.12 EGC33697.1 - 1.7e-150 489.0 72.8 4.5e-15 55.5 0.7 12.6 10 1 0 12 12 12 12 FNIP Repeat ArsA_HSP20 PF17886.1 EGC33697.1 - 0.032 13.8 2.6 38 3.9 0.0 7.1 8 3 1 9 9 9 0 HSP20-like domain found in ArsA LRR_1 PF00560.33 EGC33697.1 - 0.056 14.0 33.7 24 6.0 0.1 11.5 8 5 1 9 9 9 0 Leucine Rich Repeat K1 PF02960.14 EGC33697.1 - 0.062 13.4 0.1 10 6.2 0.0 4.0 5 0 0 5 5 5 0 K1 glycoprotein L_lac_phage_MSP PF06488.11 EGC33697.1 - 1.5 8.0 7.0 38 3.4 0.1 4.9 5 1 1 6 6 6 0 Phage tail tube protein 14-3-3 PF00244.20 EGC33699.1 - 0.23 10.9 0.5 0.38 10.2 0.5 1.3 1 0 0 1 1 1 0 14-3-3 protein BUD22 PF09073.10 EGC33700.1 - 0.048 13.0 0.1 0.048 13.0 0.1 2.9 1 1 0 2 2 2 0 BUD22 DUF3703 PF12487.8 EGC33701.1 - 1.2 9.0 9.9 1.4 8.8 9.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3703) Pkinase PF00069.25 EGC33703.1 - 9.3e-41 139.9 0.1 9.3e-41 139.9 0.1 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33703.1 - 4.5e-37 127.7 0.2 9.1e-37 126.7 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase CDC45 PF02724.14 EGC33703.1 - 0.024 12.9 10.0 0.037 12.3 10.0 1.3 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGC33703.1 - 2.2 7.6 9.6 3.5 6.9 9.6 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Pkinase PF00069.25 EGC33705.1 - 9.9e-25 87.4 6.0 3.5e-22 79.0 0.3 3.0 1 1 1 2 2 2 2 Protein kinase domain FNIP PF05725.12 EGC33705.1 - 1.8e-13 50.4 30.4 7.9e-05 22.7 0.1 5.9 1 1 6 7 7 7 5 FNIP Repeat Pkinase_Tyr PF07714.17 EGC33705.1 - 8.2e-12 44.9 1.3 7.5e-07 28.7 0.1 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase UPF0253 PF06786.12 EGC33705.1 - 0.035 14.4 0.0 4.4 7.7 0.0 2.9 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0253) FNIP PF05725.12 EGC33706.1 - 1.6e-98 322.6 34.1 2.6e-14 53.1 0.0 7.0 1 1 5 9 9 9 9 FNIP Repeat LRR_1 PF00560.33 EGC33706.1 - 6.7e-05 22.9 4.6 26 5.9 0.0 7.1 4 3 2 6 6 6 1 Leucine Rich Repeat Peptidase_S78 PF04586.17 EGC33706.1 - 0.0028 17.8 0.0 8.4 6.5 0.0 3.7 3 1 1 4 4 4 2 Caudovirus prohead serine protease K1 PF02960.14 EGC33706.1 - 0.0046 17.1 0.0 4 7.6 0.0 3.7 2 2 3 5 5 5 1 K1 glycoprotein Phage_min_tail PF05939.13 EGC33706.1 - 0.04 14.3 0.0 23 5.4 0.0 4.5 2 2 5 7 7 7 0 Phage minor tail protein HATPase_c_4 PF13749.6 EGC33706.1 - 7.5 6.8 5.1 39 4.5 0.0 3.9 6 1 0 6 6 6 0 Putative ATP-dependent DNA helicase recG C-terminal Lin-8 PF03353.15 EGC33707.1 - 0.0057 16.3 1.9 0.0057 16.3 1.9 5.7 2 2 1 4 4 4 1 Ras-mediated vulval-induction antagonist CENP-B_dimeris PF09026.10 EGC33708.1 - 0.33 11.4 3.2 19 5.7 0.0 2.8 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TFIIA PF03153.13 EGC33708.1 - 2.2 8.2 17.2 0.92 9.4 11.7 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tsg PF04668.12 EGC33708.1 - 4.5 7.9 7.0 5.3 7.7 3.6 2.8 2 1 0 2 2 2 0 Twisted gastrulation (Tsg) protein conserved region Adap_comp_sub PF00928.21 EGC33709.1 - 9.3e-91 303.9 0.1 1.2e-90 303.5 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGC33709.1 - 3.7e-08 33.4 0.7 6.4e-08 32.6 0.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain P2 PF07194.11 EGC33709.1 - 0.062 13.4 0.1 0.16 12.1 0.1 1.6 1 0 0 1 1 1 0 P2 response regulator binding domain BLYB PF05289.11 EGC33709.1 - 0.39 10.9 2.0 0.91 9.8 2.0 1.6 1 1 0 1 1 1 0 Borrelia hemolysin accessory protein DDHD PF02862.17 EGC33710.1 - 6.8e-09 36.2 7.9 1.7e-08 34.9 7.9 1.7 1 1 0 1 1 1 1 DDHD domain NUSAP PF16006.5 EGC33710.1 - 1.3 8.8 17.9 1.3 8.8 4.8 2.3 1 1 1 2 2 2 0 Nucleolar and spindle-associated protein Glyco_transf_8 PF01501.20 EGC33711.1 - 0.00076 19.1 2.8 0.00076 19.1 2.8 2.4 2 1 0 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGC33711.1 - 0.054 12.8 0.2 0.1 11.9 0.2 1.4 1 0 0 1 1 1 0 Mannosyltransferase putative Citrate_synt PF00285.21 EGC33712.1 - 3.5e-133 444.1 0.0 4.2e-133 443.9 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Ras PF00071.22 EGC33713.1 - 1.8e-54 183.7 0.0 2.1e-54 183.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33713.1 - 9.6e-22 77.5 0.0 1.5e-21 76.8 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC33713.1 - 2.6e-09 36.8 0.0 3.5e-09 36.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC33713.1 - 0.00032 20.3 0.0 0.0014 18.2 0.0 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain LRR_8 PF13855.6 EGC33714.1 - 2.3e-10 40.1 30.2 9.3e-07 28.5 8.5 5.7 3 2 3 6 6 6 5 Leucine rich repeat LRR_4 PF12799.7 EGC33714.1 - 9.4e-06 25.9 60.9 4.4e-05 23.8 8.6 7.3 4 1 3 8 8 8 6 Leucine Rich repeats (2 copies) Ank_4 PF13637.6 EGC33717.1 - 6.7e-27 93.5 2.3 1.8e-10 41.1 0.0 3.9 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC33717.1 - 1.5e-22 78.9 1.0 1.2e-07 31.9 0.0 4.3 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.7 EGC33717.1 - 7.7e-21 74.5 0.1 6.6e-17 61.9 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC33717.1 - 1.1e-18 65.4 0.4 2.9e-05 24.1 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.6 EGC33717.1 - 2.2e-14 53.3 0.4 7.2e-08 32.6 0.1 3.1 1 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4792 PF16040.5 EGC33717.1 - 0.17 11.8 0.0 1.5 8.7 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4792) DSPc PF00782.20 EGC33718.1 - 1.5e-24 86.3 0.1 1.5e-24 86.3 0.1 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Pkinase PF00069.25 EGC33718.1 - 2.9e-23 82.6 0.0 1.1e-22 80.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33718.1 - 3.4e-12 46.2 0.0 6.3e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA_Me_trans PF03054.16 EGC33720.1 - 2.5e-96 322.6 0.1 3e-96 322.3 0.1 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.17 EGC33720.1 - 0.00045 19.4 0.0 0.002 17.3 0.0 2.0 2 1 0 2 2 2 1 NAD synthase Asn_synthase PF00733.21 EGC33720.1 - 0.13 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ThiI PF02568.14 EGC33720.1 - 0.18 11.4 0.0 1.3 8.6 0.0 2.1 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) ORF6C PF10552.9 EGC33720.1 - 0.3 11.2 0.1 0.3 11.2 0.1 2.4 4 0 0 4 4 4 0 ORF6C domain PA14 PF07691.12 EGC33722.1 - 1.8e-07 31.1 0.1 3e-07 30.3 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33722.1 - 7.6e-05 22.5 12.3 7.6e-05 22.5 12.3 6.9 6 0 0 6 6 6 3 Dictyostelium (slime mold) repeat Ribosomal_S3Ae PF01015.18 EGC33723.1 - 3.6e-79 265.0 2.5 4.6e-79 264.7 2.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.16 EGC33723.1 - 0.011 15.2 0.0 0.028 14.0 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Mito_carr PF00153.27 EGC33724.1 - 1e-72 240.2 0.8 1.4e-26 92.2 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Dicty_CTDC PF00526.18 EGC33725.1 - 2.8e-17 62.3 59.0 6.5e-09 35.5 9.4 7.3 7 0 0 7 7 7 4 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC33725.1 - 4.4e-08 33.1 0.1 7.5e-08 32.3 0.1 1.3 1 0 0 1 1 1 1 PA14 domain zf-RING_2 PF13639.6 EGC33728.1 - 2.8e-09 37.2 11.3 5.3e-09 36.3 11.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33728.1 - 1.1e-08 34.8 10.8 2e-08 33.9 10.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33728.1 - 1.7e-08 34.2 11.7 4.6e-08 32.8 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33728.1 - 1.1e-06 28.9 8.7 3.4e-06 27.2 8.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC33728.1 - 7.1e-06 25.8 8.2 1.2e-05 25.1 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33728.1 - 9.2e-05 22.4 5.0 0.00024 21.1 5.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC33728.1 - 0.00021 21.2 10.9 0.00043 20.2 10.9 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC33728.1 - 0.00036 20.6 8.5 0.001 19.2 8.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC33728.1 - 0.0012 18.6 7.1 0.0031 17.3 7.1 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC33728.1 - 0.011 15.5 9.7 0.026 14.3 9.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EGC33728.1 - 0.021 15.0 3.6 0.099 12.8 3.6 2.2 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-ANAPC11 PF12861.7 EGC33728.1 - 0.041 14.0 3.6 0.077 13.1 3.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC33728.1 - 0.072 13.2 4.2 0.17 12.0 4.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_11 PF17123.5 EGC33728.1 - 1.9 8.3 10.6 3.7 7.4 10.6 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 EGC33728.1 - 3.6 7.4 8.6 6.6 6.6 8.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger IBR PF01485.21 EGC33728.1 - 4.7 7.5 12.7 21 5.5 12.2 2.3 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Zn_ribbon_17 PF17120.5 EGC33728.1 - 6.2 6.5 7.9 11 5.7 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Gpi16 PF04113.14 EGC33729.1 - 2.2e-15 56.1 0.1 2.2e-15 56.1 0.1 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component DUF1676 PF07898.13 EGC33730.1 - 0.12 12.4 0.5 0.13 12.3 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1676) MFS_1 PF07690.16 EGC33731.1 - 6.7e-24 84.5 40.1 4.3e-23 81.8 6.5 2.8 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC33731.1 - 4.5e-11 42.3 9.0 4.5e-11 42.3 9.0 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_4 PF06779.14 EGC33731.1 - 2.3e-05 23.9 0.4 4.3e-05 23.0 0.4 1.5 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB TRI12 PF06609.13 EGC33731.1 - 0.00074 18.1 0.4 0.00074 18.1 0.4 1.9 2 1 1 3 3 3 1 Fungal trichothecene efflux pump (TRI12) TypeIII_RM_meth PF12564.8 EGC33731.1 - 0.098 12.8 0.7 0.26 11.4 0.1 2.0 2 0 0 2 2 2 0 Type III restriction/modification enzyme methylation subunit HTH_29 PF13551.6 EGC33732.1 - 5.1e-05 23.2 0.1 0.00013 21.9 0.1 1.7 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.6 EGC33732.1 - 0.00012 22.1 1.1 0.00026 21.0 0.0 2.2 3 0 0 3 3 3 1 Helix-turn-helix domain HTH_23 PF13384.6 EGC33732.1 - 0.00045 19.9 1.1 0.0014 18.4 0.1 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_psq PF05225.16 EGC33732.1 - 0.0012 18.6 0.0 0.0025 17.5 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain CENP-B_N PF04218.13 EGC33732.1 - 0.0026 17.3 0.1 0.0077 15.8 0.1 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_32 PF13565.6 EGC33732.1 - 0.0029 18.2 0.1 0.012 16.2 0.1 2.1 1 0 0 1 1 1 1 Homeodomain-like domain HTH_Tnp_ISL3 PF13542.6 EGC33732.1 - 0.0081 15.5 0.0 0.021 14.2 0.0 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain of transposase family ISL3 HTH_Tnp_1 PF01527.20 EGC33732.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Transposase LysM PF01476.20 EGC33732.1 - 0.039 14.0 0.0 0.12 12.4 0.0 1.9 1 0 0 1 1 1 0 LysM domain HTH_11 PF08279.12 EGC33732.1 - 0.16 11.9 0.7 0.46 10.5 0.1 2.0 2 0 0 2 2 2 0 HTH domain DEAD PF00270.29 EGC33733.1 - 5.2e-45 153.3 0.0 1.3e-44 152.1 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC33733.1 - 9.1e-23 80.7 0.0 1.9e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SPRY PF00622.28 EGC33733.1 - 6e-22 78.0 0.8 1.2e-21 77.0 0.8 1.5 1 0 0 1 1 1 1 SPRY domain UTP25 PF06862.12 EGC33733.1 - 0.00019 20.4 0.5 1.3 7.7 0.1 3.2 3 0 0 3 3 3 3 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 CMS1 PF14617.6 EGC33733.1 - 0.24 10.7 0.1 0.24 10.7 0.1 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ketoacyl-synt PF00109.26 EGC33734.1 - 3.2e-65 220.2 0.0 4.9e-65 219.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC33734.1 - 7.3e-42 144.0 0.0 1.2e-41 143.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC33734.1 - 6.6e-31 106.8 0.0 9.1e-30 103.1 0.0 2.6 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC33734.1 - 2e-27 96.2 0.1 4.4e-27 95.1 0.1 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC33734.1 - 2.2e-21 76.4 5.2 5.2e-21 75.2 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC33734.1 - 1.1e-17 64.2 0.0 1.7e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC33734.1 - 1.7e-14 54.2 0.0 6.2e-14 52.4 0.0 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC33734.1 - 1e-09 39.5 0.0 5.2e-09 37.2 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC33734.1 - 7.3e-06 25.8 0.1 1.8e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC33734.1 - 9.4e-06 26.2 0.0 3.3e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC33734.1 - 4e-05 24.2 0.0 0.00021 21.9 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC33734.1 - 6.4e-05 22.4 0.1 0.00026 20.4 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC33734.1 - 0.0001 22.2 0.0 0.00028 20.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC33734.1 - 0.00017 21.4 3.7 0.087 12.6 0.0 4.0 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGC33734.1 - 0.007 16.3 0.0 0.041 13.9 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGC33734.1 - 0.0082 16.5 0.6 0.022 15.1 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EGC33734.1 - 0.02 14.4 0.1 0.061 12.8 0.1 1.9 1 0 0 1 1 1 0 short chain dehydrogenase GDP_Man_Dehyd PF16363.5 EGC33734.1 - 0.057 12.8 2.9 0.034 13.6 0.3 2.0 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase ABC_tran_CTD PF16326.5 EGC33736.1 - 0.028 14.7 1.4 4.2 7.7 0.4 2.3 2 0 0 2 2 2 0 ABC transporter C-terminal domain ABC_membrane_3 PF13748.6 EGC33737.1 - 0.25 10.6 2.8 0.38 9.9 2.8 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region SurA_N_2 PF13623.6 EGC33737.1 - 0.65 9.9 12.6 1.5 8.7 9.7 1.9 1 1 1 2 2 2 0 SurA N-terminal domain Chromo PF00385.24 EGC33739.1 - 6.6e-08 32.3 0.6 1.2e-07 31.5 0.6 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EGC33739.1 - 0.11 12.4 1.9 0.2 11.6 1.9 1.5 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.6 EGC33740.1 - 2.8e-09 37.2 10.9 5.1e-09 36.3 10.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC33740.1 - 1.2e-08 34.6 10.8 2.1e-08 33.8 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33740.1 - 1.6e-08 34.2 11.7 4.8e-08 32.7 11.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC33740.1 - 1.6e-07 31.5 7.7 5.2e-07 29.9 7.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC33740.1 - 3.2e-06 26.9 7.5 5.3e-06 26.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33740.1 - 0.00011 22.2 5.0 0.00025 21.0 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC33740.1 - 0.00024 21.0 10.9 0.00045 20.1 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC33740.1 - 0.00039 20.5 8.5 0.001 19.1 8.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TAP42 PF04177.12 EGC33740.1 - 0.00083 18.6 11.4 0.00083 18.6 11.4 3.4 4 0 0 4 4 3 1 TAP42-like family Prok-RING_4 PF14447.6 EGC33740.1 - 0.0014 18.5 7.2 0.0032 17.3 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC33740.1 - 0.013 15.3 9.7 0.027 14.2 9.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC33740.1 - 0.023 14.8 2.9 0.045 13.8 2.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC33740.1 - 1.9 8.3 10.6 3.9 7.3 10.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC33740.1 - 2.8 7.7 7.6 4.6 6.9 7.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-MIZ PF02891.20 EGC33740.1 - 3.1 7.6 8.1 5.7 6.8 8.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FNIP PF05725.12 EGC33741.1 - 1.6e-05 25.0 10.3 1.6e-05 25.0 10.3 12.1 9 2 3 12 12 12 5 FNIP Repeat GOLD_2 PF13897.6 EGC33741.1 - 0.029 14.9 0.2 0.066 13.7 0.2 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking C9orf72-like PF15019.6 EGC33742.1 - 2.9e-27 95.8 1.7 3.9e-27 95.4 1.7 1.1 1 0 0 1 1 1 1 C9orf72-like protein family COX5B PF01215.19 EGC33743.1 - 1.2e-11 44.4 0.0 1.5e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-CHCC PF10276.9 EGC33743.1 - 0.0024 17.9 0.1 0.0042 17.1 0.1 1.4 1 0 0 1 1 1 1 Zinc-finger domain HPP PF04982.13 EGC33744.1 - 6e-41 139.4 9.2 1.6e-40 138.1 8.6 1.8 2 0 0 2 2 2 1 HPP family Baculo_LEF5 PF04838.12 EGC33745.1 - 0.0049 16.9 0.3 0.0053 16.8 0.3 1.0 1 0 0 1 1 1 1 Baculoviridae late expression factor 5 2OG-FeII_Oxy_2 PF13532.6 EGC33746.1 - 0.011 16.0 0.0 0.028 14.6 0.0 1.6 1 1 1 2 2 2 0 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.22 EGC33747.1 - 1.6e-20 72.7 0.1 6.4e-13 48.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.23 EGC33747.1 - 1.9e-13 50.1 3.3 4.1e-13 49.0 3.3 1.6 1 0 0 1 1 1 1 G-patch domain OCRE PF17780.1 EGC33747.1 - 1.9e-07 31.0 21.4 1.9e-07 31.0 21.4 2.4 2 0 0 2 2 2 1 OCRE domain zf-RanBP PF00641.18 EGC33747.1 - 2.9e-06 26.5 5.2 7.6e-06 25.1 5.2 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.7 EGC33747.1 - 3.1e-05 24.0 1.2 3.1e-05 24.0 1.2 3.0 2 1 1 3 3 3 1 G-patch domain zf-C2H2_4 PF13894.6 EGC33747.1 - 0.21 12.5 0.2 0.21 12.5 0.2 2.2 2 0 0 2 2 2 0 C2H2-type zinc finger TIG PF01833.24 EGC33748.1 - 2.7e-10 40.2 38.1 1.5e-05 25.0 2.4 5.7 5 2 1 6 6 6 3 IPT/TIG domain EGF_2 PF07974.13 EGC33748.1 - 5e-09 36.4 48.7 0.00046 20.5 11.3 4.6 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.7 EGC33748.1 - 0.0048 17.5 31.1 0.046 14.4 4.5 4.6 3 0 0 3 3 3 2 Human growth factor-like EGF Laminin_EGF PF00053.24 EGC33748.1 - 0.07 13.3 36.1 0.71 10.1 8.0 4.0 3 0 0 3 3 3 0 Laminin EGF domain SKG6 PF08693.10 EGC33748.1 - 0.82 9.1 4.0 0.63 9.5 1.8 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain zf-Tim10_DDP PF02953.15 EGC33748.1 - 4 7.2 8.0 20 4.9 0.1 3.5 3 0 0 3 3 3 0 Tim10/DDP family zinc finger TIG PF01833.24 EGC33749.1 - 8.5e-06 25.8 1.6 8.5e-06 25.8 1.6 4.6 4 2 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC33749.1 - 0.00023 21.5 30.6 0.0005 20.4 11.3 3.2 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.24 EGC33749.1 - 0.13 12.5 21.4 2 8.6 8.3 2.8 2 0 0 2 2 2 0 Laminin EGF domain EGF PF00008.27 EGC33749.1 - 4.9 7.5 25.0 6.6 7.1 9.1 3.7 2 2 0 2 2 2 0 EGF-like domain LRR_6 PF13516.6 EGC33749.1 - 6.6 7.1 7.8 1.8 8.8 1.4 3.6 3 0 0 3 3 3 0 Leucine Rich repeat EGF_2 PF07974.13 EGC33750.1 - 3.2e-06 27.4 65.1 0.00059 20.1 11.3 5.0 4 0 0 4 4 4 3 EGF-like domain Laminin_EGF PF00053.24 EGC33750.1 - 1.1 9.5 48.7 1.1 9.4 5.4 4.8 4 0 0 4 4 4 0 Laminin EGF domain TIG PF01833.24 EGC33751.1 - 7.3e-12 45.2 34.7 1.1e-05 25.4 2.4 5.6 5 1 0 5 5 5 3 IPT/TIG domain EGF_2 PF07974.13 EGC33751.1 - 2e-08 34.5 48.5 0.0006 20.1 12.4 4.5 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.7 EGC33751.1 - 0.0003 21.3 27.0 0.085 13.5 4.0 4.6 3 0 0 3 3 3 2 Human growth factor-like EGF LPD15 PF18828.1 EGC33751.1 - 0.16 11.8 0.1 32 4.5 0.0 2.6 2 0 0 2 2 2 0 Large polyvalent-protein-associated domain 15 Laminin_EGF PF00053.24 EGC33751.1 - 0.22 11.7 36.5 1.8 8.8 8.9 4.0 3 0 0 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC33752.1 - 0.00072 19.9 12.4 0.00072 19.9 12.4 3.0 2 0 0 2 2 2 1 EGF-like domain Cytomega_US3 PF05963.11 EGC33752.1 - 0.06 13.0 0.0 0.13 11.9 0.0 1.5 1 0 0 1 1 1 0 Cytomegalovirus US3 protein Laminin_EGF PF00053.24 EGC33752.1 - 0.12 12.6 24.3 1.6 8.9 10.2 2.8 2 0 0 2 2 2 0 Laminin EGF domain Fungal_KA1 PF16797.5 EGC33752.1 - 1.2 8.8 4.2 6.8 6.4 0.0 3.5 4 0 0 4 4 4 0 Fungal kinase associated-1 domain Orn_Arg_deC_N PF02784.16 EGC33753.1 - 3.7e-77 259.0 0.0 5.1e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGC33753.1 - 4e-18 65.5 0.0 5.6e-18 65.0 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.24 EGC33753.1 - 0.00011 21.8 0.0 0.00019 20.9 0.0 1.3 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF5448 PF17526.2 EGC33753.1 - 0.1 12.8 0.0 0.23 11.7 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5448) LRR_9 PF14580.6 EGC33754.1 - 5e-09 35.9 1.5 5e-09 35.9 1.5 2.8 2 1 1 3 3 3 2 Leucine-rich repeat LRR_4 PF12799.7 EGC33754.1 - 8.3e-08 32.4 12.0 5.7e-05 23.4 2.6 4.0 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC33754.1 - 0.00019 21.1 0.2 0.00019 21.1 0.2 2.7 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.33 EGC33754.1 - 0.16 12.6 3.1 14 6.7 0.1 4.2 3 0 0 3 3 3 0 Leucine Rich Repeat NARP1 PF12569.8 EGC33754.1 - 0.52 9.2 20.4 0.89 8.4 20.4 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 GAGA_bind PF06217.12 EGC33754.1 - 0.56 10.4 10.0 0.082 13.2 6.3 1.6 2 0 0 2 2 2 0 GAGA binding protein-like family LRR_6 PF13516.6 EGC33754.1 - 0.93 9.7 5.7 16 5.9 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich repeat Vma12 PF11712.8 EGC33754.1 - 2.4 8.3 9.5 5.6 7.0 9.5 1.7 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF1682 PF07946.14 EGC33754.1 - 3.5 6.7 19.4 5.4 6.1 19.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) DUF963 PF06131.11 EGC33754.1 - 4 6.9 6.7 0.99 8.9 2.9 1.9 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Membralin PF09746.9 EGC33754.1 - 8.3 5.3 6.0 13 4.7 6.0 1.4 1 0 0 1 1 1 0 Tumour-associated protein Mannosyl_trans2 PF04188.13 EGC33755.1 - 1.2e-66 225.9 42.2 2.4e-39 135.9 17.5 2.7 2 1 0 2 2 2 2 Mannosyltransferase (PIG-V) HSCB_C PF07743.13 EGC33756.1 - 7.4e-21 74.4 5.6 2e-20 73.1 3.0 2.4 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.31 EGC33756.1 - 3.6e-05 23.8 0.5 0.00013 22.0 0.5 1.9 1 0 0 1 1 1 1 DnaJ domain zinc_ribbon_15 PF17032.5 EGC33756.1 - 0.0039 17.9 1.6 0.0083 16.9 1.6 1.6 1 0 0 1 1 1 1 zinc-ribbon family DZR PF12773.7 EGC33756.1 - 0.018 15.1 1.0 0.031 14.3 1.0 1.3 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.6 EGC33756.1 - 0.05 13.0 2.0 0.095 12.1 1.8 1.6 1 1 0 1 1 1 0 zinc-ribbon domain MapZ_EC1 PF18041.1 EGC33756.1 - 0.055 13.7 0.7 0.055 13.7 0.7 2.8 3 0 0 3 3 3 0 MapZ extracellular domain 1 zinc_ribbon_2 PF13240.6 EGC33756.1 - 0.096 12.4 3.9 0.21 11.4 3.9 1.6 1 0 0 1 1 1 0 zinc-ribbon domain zf-C3HC4_3 PF13920.6 EGC33756.1 - 0.24 11.3 3.3 0.41 10.6 3.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PfkB PF00294.24 EGC33757.1 - 6.3e-57 193.2 0.4 7.1e-57 193.0 0.4 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.12 EGC33757.1 - 0.012 15.0 0.2 0.024 14.0 0.0 1.5 2 0 0 2 2 2 0 Phosphomethylpyrimidine kinase ABC2_membrane PF01061.24 EGC33758.1 - 6.1e-86 287.2 51.3 8.7e-49 165.8 15.6 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC33758.1 - 1.8e-37 128.9 0.0 2.2e-18 67.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGC33758.1 - 6.8e-24 83.6 15.1 1.9e-21 75.7 0.2 3.6 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC33758.1 - 1.5e-07 31.9 0.0 3.4e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGC33758.1 - 2.2e-06 27.7 0.2 0.00045 20.2 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGC33758.1 - 2.4e-06 28.1 0.0 0.0059 17.0 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.6 EGC33758.1 - 3.5e-06 27.1 0.4 0.01 15.7 0.0 3.0 4 0 0 4 4 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC33758.1 - 6.5e-06 25.8 0.5 0.0052 16.5 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC33758.1 - 0.00011 22.4 0.0 0.086 13.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC33758.1 - 0.00025 20.7 0.2 0.0012 18.5 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC33758.1 - 0.00037 21.1 0.1 0.42 11.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC33758.1 - 0.0011 19.0 0.1 2.5 8.2 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGC33758.1 - 0.0023 18.1 0.1 0.84 9.8 0.0 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.7 EGC33758.1 - 0.0025 17.0 59.2 0.0089 15.2 19.5 3.7 2 2 1 3 3 3 2 ABC-2 family transporter protein AAA_23 PF13476.6 EGC33758.1 - 0.023 15.2 1.2 0.79 10.2 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC33758.1 - 0.065 12.9 3.1 2.1 8.0 0.5 2.7 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.12 EGC33758.1 - 0.067 12.5 0.0 6.6 5.9 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin cobW PF02492.19 EGC33758.1 - 0.075 12.6 0.8 2.8 7.5 0.6 2.3 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Rad17 PF03215.15 EGC33758.1 - 0.076 12.9 0.1 8.6 6.2 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_28 PF13521.6 EGC33758.1 - 0.16 12.2 3.0 0.28 11.4 0.7 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGC33758.1 - 0.2 11.6 1.2 5.6 6.8 0.5 2.4 2 0 0 2 2 2 0 NACHT domain ABC2_membrane_2 PF12679.7 EGC33758.1 - 3.4 6.8 16.9 0.56 9.4 7.6 2.7 3 0 0 3 3 3 0 ABC-2 family transporter protein Actin PF00022.19 EGC33759.1 - 1e-140 469.0 0.0 1.2e-140 468.8 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGC33759.1 - 4.5e-09 35.6 0.0 4.2e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Glyco_transf_24 PF18404.1 EGC33759.1 - 0.15 11.5 0.0 0.4 10.0 0.0 1.7 1 0 0 1 1 1 0 Glucosyltransferase 24 Tweety PF04906.13 EGC33760.1 - 5.5e-12 45.1 8.8 7.4e-09 34.8 1.5 2.3 1 1 1 2 2 2 2 Tweety DUF2207 PF09972.9 EGC33760.1 - 0.0087 14.9 0.9 0.0087 14.9 0.9 3.0 2 1 0 2 2 2 1 Predicted membrane protein (DUF2207) ETRAMP PF09716.10 EGC33760.1 - 0.11 12.6 6.4 1.1 9.3 0.2 4.1 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) EphA2_TM PF14575.6 EGC33760.1 - 5.2 8.0 7.5 5.9 7.9 0.9 3.8 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain KAR9 PF08580.10 EGC33762.1 - 0.19 10.2 6.1 0.2 10.1 6.1 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 DUF1514 PF07438.11 EGC33762.1 - 0.28 11.1 0.1 0.28 11.1 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1514) Mucin PF01456.17 EGC33762.1 - 0.41 10.6 15.7 1.7 8.6 16.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3430 PF11912.8 EGC33763.1 - 0.045 13.8 13.2 0.4 10.7 13.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) Prenylcys_lyase PF07156.14 EGC33764.1 - 7.9e-70 235.8 2.4 9.8e-70 235.5 2.4 1.1 1 0 0 1 1 1 1 Prenylcysteine lyase Amino_oxidase PF01593.24 EGC33764.1 - 7.1e-08 32.2 0.0 1e-07 31.7 0.0 1.1 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC33764.1 - 1.3e-05 25.3 1.0 2.3e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_dh_N PF08501.11 EGC33764.1 - 0.0016 18.7 0.1 0.55 10.5 0.0 2.9 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain Fer4_12 PF13353.6 EGC33764.1 - 0.071 13.4 0.1 1.7 8.9 0.0 2.4 2 0 0 2 2 2 0 4Fe-4S single cluster domain Pyr_redox_2 PF07992.14 EGC33764.1 - 0.086 12.1 0.1 0.84 8.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FDC-SP PF15215.6 EGC33764.1 - 0.24 12.0 1.5 1.8 9.2 0.0 2.6 3 0 0 3 3 3 0 Follicular dendritic cell secreted peptide Coiled PF05710.12 EGC33765.1 - 0.0015 19.3 9.5 0.002 18.9 9.5 1.3 1 0 0 1 1 1 1 Coiled coil FtsX PF02687.21 EGC33767.1 - 2.5e-13 50.3 21.6 2.5e-09 37.5 5.9 6.2 6 1 0 6 6 6 2 FtsX-like permease family DUF2649 PF10854.8 EGC33767.1 - 7.1 7.0 16.1 0.64 10.4 1.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF2649) Radical_SAM PF04055.21 EGC33768.1 - 1.2e-32 113.6 0.1 3.7e-32 112.0 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.20 EGC33768.1 - 3.2e-31 107.3 0.2 6.5e-31 106.3 0.2 1.6 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.20 EGC33768.1 - 3.1e-08 33.5 0.2 6.9e-08 32.4 0.2 1.7 1 0 0 1 1 1 1 TRAM domain BORCS7 PF16088.5 EGC33770.1 - 0.018 15.3 0.1 0.035 14.3 0.1 1.5 1 1 0 1 1 1 0 BLOC-1-related complex sub-unit 7 RAB3GAP2_C PF14656.6 EGC33770.1 - 0.39 8.9 3.2 0.54 8.4 3.2 1.2 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit C-terminus DNA_pol_phi PF04931.13 EGC33770.1 - 0.53 8.3 13.7 0.58 8.2 13.7 1.1 1 0 0 1 1 1 0 DNA polymerase phi UFC1 PF08694.11 EGC33770.1 - 1.8 8.2 6.5 7.4 6.2 1.8 2.2 1 1 1 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 RPA43_OB PF17875.1 EGC33770.1 - 9.6 6.9 12.2 49 4.6 12.2 2.1 1 1 0 1 1 1 0 RPA43 OB domain in RNA Pol I PRIMA1 PF16101.5 EGC33771.1 - 2.7 8.0 9.2 6.3 6.9 9.2 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Thioredoxin PF00085.20 EGC33772.1 - 5e-09 36.1 0.0 1.3e-08 34.8 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin TPR_12 PF13424.6 EGC33773.1 - 1e-24 86.6 0.0 9.6e-07 29.0 0.0 5.2 3 1 3 6 6 6 5 Tetratricopeptide repeat TPR_2 PF07719.17 EGC33773.1 - 7e-10 38.3 5.1 1.5 9.1 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGC33773.1 - 1.5e-08 34.3 0.6 0.066 13.1 0.0 5.2 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC33773.1 - 1.8e-08 34.1 0.0 0.0014 18.1 0.0 3.1 2 1 1 3 3 3 2 MalT-like TPR region TPR_8 PF13181.6 EGC33773.1 - 2.7e-08 33.4 15.4 0.4 11.0 0.0 7.9 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGC33773.1 - 1.2e-05 25.8 0.0 0.71 10.9 0.0 5.0 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC33773.1 - 0.00015 22.2 0.1 5.6 7.6 0.0 4.2 4 1 0 4 4 4 1 Tetratricopeptide repeat ANAPC5 PF12862.7 EGC33773.1 - 0.00019 21.5 1.5 1.5 8.9 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 5 Ribosomal_S7 PF00177.21 EGC33773.1 - 0.092 12.4 0.2 4.5 6.9 0.0 3.4 1 1 2 3 3 3 0 Ribosomal protein S7p/S5e TPR_1 PF00515.28 EGC33773.1 - 0.14 12.1 0.0 0.14 12.1 0.0 6.0 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC33773.1 - 1.7 9.2 7.3 9.4 6.9 0.1 4.8 4 1 0 4 4 4 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.17 EGC33774.1 - 0.78 10.4 7.4 1.1 9.9 0.8 2.8 3 0 0 3 3 3 0 HSF-type DNA-binding Ribosomal_L34e PF01199.18 EGC33776.1 - 1.4e-43 147.1 4.0 1.4e-43 147.1 4.0 1.6 2 0 0 2 2 2 1 Ribosomal protein L34e Nkap_C PF06047.11 EGC33776.1 - 0.057 13.5 2.0 0.5 10.5 2.0 2.0 1 1 0 1 1 1 0 NF-kappa-B-activating protein C-terminal domain UQ_con PF00179.26 EGC33777.1 - 6.7e-40 136.0 0.0 7.6e-40 135.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme BPS PF08947.10 EGC33777.1 - 0.23 11.3 0.4 17 5.4 0.1 2.2 2 0 0 2 2 2 0 BPS (Between PH and SH2) RRM_1 PF00076.22 EGC33778.1 - 1.1e-18 66.8 0.0 2.6e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC33778.1 - 0.048 13.5 0.0 0.096 12.6 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Asn_synthase PF00733.21 EGC33780.1 - 8.6e-70 236.2 0.0 1.3e-69 235.6 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGC33780.1 - 1.9e-42 144.0 0.0 4.2e-42 142.9 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC33780.1 - 4.6e-34 117.5 0.0 7.8e-34 116.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC33780.1 - 1.1e-05 25.0 0.0 2.5e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Aluminium induced protein DUF4144 PF13642.6 EGC33780.1 - 0.023 15.3 0.7 0.096 13.3 0.7 2.1 1 0 0 1 1 1 0 protein structure with unknown function DNA_pol_A_exo1 PF01612.20 EGC33781.1 - 3.3e-08 33.4 0.0 5.3e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease Metallophos_2 PF12850.7 EGC33782.1 - 3.3e-17 63.2 0.0 7.6e-17 62.0 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGC33782.1 - 2.7e-15 57.4 1.2 3.5e-15 57.1 1.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.6 EGC33782.1 - 7.1e-12 45.2 0.3 1.1e-09 38.0 0.3 2.9 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily DUF4121 PF13497.6 EGC33782.1 - 0.02 14.0 0.1 0.033 13.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) PPR_long PF17177.4 EGC33782.1 - 0.099 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Pentacotripeptide-repeat region of PRORP Kelch_4 PF13418.6 EGC33783.1 - 1.6e-37 127.3 10.0 2.2e-08 34.0 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC33783.1 - 1.3e-29 101.4 15.8 5.7e-06 26.4 0.1 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_1 PF01344.25 EGC33783.1 - 4.4e-28 96.6 7.6 0.00013 21.4 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC33783.1 - 3.7e-27 93.2 12.1 8.8e-06 25.5 0.5 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGC33783.1 - 4.2e-27 93.8 18.2 5.1e-07 29.8 0.2 7.0 7 0 0 7 7 6 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC33783.1 - 1.4e-25 88.7 8.1 1.6e-06 28.0 0.0 6.5 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.17 EGC33783.1 - 1.6e-08 34.5 0.4 3.5e-08 33.4 0.4 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC33783.1 - 4.9e-08 33.3 0.1 8.9e-08 32.5 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mucin PF01456.17 EGC33783.1 - 0.026 14.5 12.7 0.046 13.7 12.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 EGC33783.1 - 3.7 6.0 18.9 5.2 5.5 18.9 1.2 1 0 0 1 1 1 0 Macoilin family Menin PF05053.13 EGC33783.1 - 8.2 4.7 12.8 14 3.8 12.8 1.3 1 0 0 1 1 1 0 Menin XPC-binding PF09280.11 EGC33784.1 - 1.9e-19 69.1 5.3 3.3e-19 68.4 5.3 1.4 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.31 EGC33784.1 - 2e-19 69.1 4.4 1.3e-09 37.8 0.3 2.4 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.23 EGC33784.1 - 3.5e-19 68.3 0.7 6.6e-19 67.4 0.4 1.7 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EGC33784.1 - 1.8e-06 27.7 0.7 3.7e-06 26.7 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGC33784.1 - 0.0006 19.9 0.0 0.0018 18.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like PARM PF17061.5 EGC33784.1 - 0.00061 20.0 15.5 0.00077 19.7 15.5 1.1 1 0 0 1 1 1 1 PARM UBA_3 PF09288.10 EGC33784.1 - 0.001 18.8 0.1 0.011 15.5 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain SOG2 PF10428.9 EGC33784.1 - 0.0033 16.7 6.5 0.0041 16.4 6.5 1.2 1 0 0 1 1 1 1 RAM signalling pathway protein MCM_N PF14551.6 EGC33784.1 - 0.0035 17.9 0.0 0.0068 17.0 0.0 1.5 1 0 0 1 1 1 1 MCM N-terminal domain DUF2407 PF10302.9 EGC33784.1 - 0.042 14.4 0.0 0.11 13.0 0.0 1.8 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Hamartin PF04388.12 EGC33784.1 - 0.095 11.4 7.2 0.11 11.1 7.2 1.1 1 0 0 1 1 1 0 Hamartin protein HNF-1_N PF04814.13 EGC33784.1 - 0.35 11.4 2.8 0.92 10.1 2.0 2.0 2 0 0 2 2 2 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Ndc1_Nup PF09531.10 EGC33784.1 - 1 8.0 3.8 1.1 7.9 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nucleo_P87 PF07267.11 EGC33784.1 - 1.1 8.0 5.3 1.4 7.6 5.3 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Neisseria_TspB PF05616.13 EGC33784.1 - 1.2 7.5 13.2 1.7 7.0 13.2 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein QWRF PF04484.12 EGC33784.1 - 3.9 7.1 6.0 5.5 6.6 6.0 1.2 1 0 0 1 1 1 0 QWRF family ATF7IP_BD PF16788.5 EGC33784.1 - 9.5 6.3 13.7 15 5.6 13.7 1.2 1 0 0 1 1 1 0 ATF-interacting protein binding domain PhoPQ_related PF10142.9 EGC33785.1 - 1.2e-104 349.9 2.5 1.5e-104 349.6 2.5 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein EF_TS PF00889.19 EGC33786.1 - 1.4e-35 122.8 2.2 2.4e-33 115.5 0.2 2.7 2 1 0 2 2 2 1 Elongation factor TS UBA PF00627.31 EGC33786.1 - 0.00012 21.8 0.0 0.00032 20.5 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.10 EGC33786.1 - 0.036 14.4 1.3 0.053 13.8 0.1 1.9 2 0 0 2 2 2 0 HBS1 N-terminus UBA_4 PF14555.6 EGC33786.1 - 0.041 13.7 0.0 0.081 12.8 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain RRM_1 PF00076.22 EGC33787.1 - 7.2e-34 115.4 0.0 1.8e-16 59.7 0.0 3.8 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC33787.1 - 4.1e-07 30.0 0.0 0.0018 18.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif RRM_occluded PF16842.5 EGC33787.1 - 5.4e-05 23.0 0.0 3.2 7.7 0.0 3.6 3 0 0 3 3 3 3 Occluded RNA-recognition motif Spo7_2_N PF15407.6 EGC33787.1 - 0.033 13.8 0.0 1.9 8.2 0.0 2.4 2 0 0 2 2 2 0 Sporulation protein family 7 TcpA PF05946.12 EGC33787.1 - 0.18 11.9 0.0 0.33 11.1 0.0 1.4 1 0 0 1 1 1 0 Toxin-coregulated pilus subunit TcpA Cupin_8 PF13621.6 EGC33788.1 - 1.3e-46 159.3 5.2 1.3e-46 159.3 5.2 1.6 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGC33788.1 - 3.1e-05 23.6 0.0 5e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein RecG_N PF17190.4 EGC33788.1 - 0.015 16.0 0.6 0.049 14.4 0.1 2.2 2 1 0 2 2 2 0 RecG N-terminal helical domain P5CR_dimer PF14748.6 EGC33789.1 - 1.3e-26 92.8 0.5 2.1e-26 92.2 0.5 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGC33789.1 - 8.6e-17 61.5 0.1 2e-16 60.4 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGC33789.1 - 1.3e-06 28.6 0.1 3.1e-06 27.4 0.1 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.16 EGC33789.1 - 2.5e-06 27.2 0.7 1.2e-05 25.0 0.3 2.2 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA IlvN PF07991.12 EGC33789.1 - 0.0004 20.0 0.2 0.00064 19.3 0.2 1.5 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EGC33789.1 - 0.00062 20.0 0.1 0.0021 18.3 0.1 1.9 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_Gly3P_dh_N PF01210.23 EGC33789.1 - 0.0007 19.6 1.4 0.0078 16.2 1.4 2.2 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.18 EGC33789.1 - 0.0027 18.0 0.1 0.0062 16.8 0.0 1.7 1 1 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGC33789.1 - 0.024 14.7 0.3 0.086 12.9 0.1 1.9 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase PDH PF02153.17 EGC33789.1 - 0.051 12.6 0.2 0.086 11.8 0.2 1.3 1 0 0 1 1 1 0 Prephenate dehydrogenase PHM7_cyt PF14703.6 EGC33791.1 - 1.5 9.0 9.0 2.9 8.1 9.0 1.5 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter Isochorismatase PF00857.20 EGC33792.1 - 0.08 13.1 0.0 0.09 13.0 0.0 1.1 1 0 0 1 1 1 0 Isochorismatase family PRKCSH_1 PF13015.6 EGC33793.1 - 1.2e-05 25.1 7.1 0.02 14.6 0.1 3.3 3 0 0 3 3 3 3 Glucosidase II beta subunit-like protein EGF_Tenascin PF18720.1 EGC33797.1 - 0.004 17.2 7.6 0.011 15.7 7.6 1.8 1 0 0 1 1 1 1 Tenascin EGF domain Herpes_UL69 PF05459.12 EGC33798.1 - 0.0069 15.8 0.1 0.022 14.1 0.1 1.8 1 0 0 1 1 1 1 Herpesvirus transcriptional regulator family Rpr2 PF04032.16 EGC33799.1 - 5.9e-08 32.9 7.5 5.9e-08 32.9 7.5 2.8 2 1 0 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain CENP-O PF09496.10 EGC33799.1 - 0.04 13.9 3.6 0.056 13.4 3.6 1.1 1 0 0 1 1 1 0 Cenp-O kinetochore centromere component DZR PF12773.7 EGC33799.1 - 0.35 10.9 3.3 5.8 7.0 3.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon Menin PF05053.13 EGC33799.1 - 5.8 5.1 11.4 8.4 4.6 11.4 1.2 1 0 0 1 1 1 0 Menin Jnk-SapK_ap_N PF09744.9 EGC33800.1 - 0.014 15.6 15.9 0.014 15.6 15.9 3.3 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Golgin_A5 PF09787.9 EGC33800.1 - 0.025 14.0 29.1 0.034 13.6 29.1 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 HEPN PF05168.14 EGC33800.1 - 0.37 10.9 4.0 0.27 11.4 1.2 2.0 1 1 1 2 2 2 0 HEPN domain AAA_15 PF13175.6 EGC33800.1 - 2.2 7.9 29.3 2.7 7.6 29.3 1.1 1 0 0 1 1 1 0 AAA ATPase domain YabA PF06156.13 EGC33800.1 - 2.4 8.8 31.1 4.8 7.9 14.2 3.0 1 1 2 3 3 3 0 Initiation control protein YabA ZapB PF06005.12 EGC33800.1 - 3.5 8.1 47.6 0.45 11.0 10.4 3.6 1 1 2 3 3 3 0 Cell division protein ZapB Uso1_p115_C PF04871.13 EGC33800.1 - 4.5 7.6 34.6 1.2 9.5 9.5 3.0 1 1 1 2 2 2 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF3979 PF13141.6 EGC33801.1 - 0.15 12.3 0.1 0.15 12.3 0.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3979) RabGAP-TBC PF00566.18 EGC33801.1 - 10 5.7 9.9 5.4 6.6 0.8 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain PDZ_1 PF12812.7 EGC33802.1 - 0.055 13.5 0.2 0.15 12.1 0.1 1.7 1 1 1 2 2 2 0 PDZ-like domain CAF-1_p150 PF11600.8 EGC33802.1 - 0.71 9.5 23.5 1.3 8.7 23.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Peptidase_S64 PF08192.11 EGC33802.1 - 3.9 5.8 32.4 4.5 5.6 32.4 1.0 1 0 0 1 1 1 0 Peptidase family S64 CDC45 PF02724.14 EGC33802.1 - 7.5 4.7 21.7 8.6 4.5 21.7 1.1 1 0 0 1 1 1 0 CDC45-like protein PA14 PF07691.12 EGC33803.1 - 2.8e-13 49.9 0.1 4.3e-13 49.3 0.1 1.2 1 0 0 1 1 1 1 PA14 domain DUF4326 PF14216.6 EGC33804.1 - 6e-23 81.4 0.1 1.1e-22 80.5 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) UQ_con PF00179.26 EGC33805.1 - 5.8e-37 126.5 0.0 8.6e-37 125.9 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme FSA_C PF10479.9 EGC33805.1 - 0.59 8.2 10.0 0.71 7.9 10.0 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGC33805.1 - 0.61 10.1 25.0 0.82 9.7 25.0 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein MGC-24 PF05283.11 EGC33805.1 - 2.6 8.5 12.0 3.8 7.9 12.0 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin TFIIF_alpha PF05793.12 EGC33805.1 - 2.7 6.5 9.3 3.5 6.1 9.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) UPF0052 PF01933.18 EGC33806.1 - 0.11 11.7 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family UPF0052 Alpha_kinase PF02816.18 EGC33807.1 - 2.3e-60 203.9 0.3 2.3e-60 203.9 0.3 1.9 2 0 0 2 2 2 1 Alpha-kinase family WD40 PF00400.32 EGC33807.1 - 5.2e-43 144.2 18.3 1.2e-06 29.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.8 EGC33807.1 - 2.4e-14 52.9 5.4 0.0001 21.1 0.2 5.7 2 1 4 6 6 6 4 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGC33807.1 - 1.2e-06 28.7 1.2 0.51 10.7 0.2 5.1 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain PQQ_3 PF13570.6 EGC33807.1 - 7.4e-05 23.1 0.0 54 4.5 0.0 5.7 6 0 0 6 6 6 0 PQQ-like domain HPS3_N PF14761.6 EGC33807.1 - 0.00069 19.2 0.2 9.2 5.7 0.0 4.1 2 1 2 4 4 4 2 Hermansky-Pudlak syndrome 3 Ge1_WD40 PF16529.5 EGC33807.1 - 0.0036 16.3 6.7 0.54 9.2 0.7 3.2 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein LVIVD PF08309.11 EGC33807.1 - 0.015 14.6 0.2 0.26 10.6 0.0 3.0 4 0 0 4 4 4 0 LVIVD repeat FNIP PF05725.12 EGC33808.1 - 6.9e-82 269.4 32.1 9.4e-16 57.7 0.2 7.6 3 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.10 EGC33808.1 - 0.0088 16.2 4.8 20 5.5 0.1 6.4 5 3 3 8 8 8 1 Protein of unknown function (DUF1769) Roughex PF06020.11 EGC33809.1 - 2.3 7.3 11.8 3.4 6.7 11.8 1.3 1 0 0 1 1 1 0 Drosophila roughex protein Androgen_recep PF02166.16 EGC33809.1 - 7.3 5.3 19.8 2.1 7.1 16.9 1.4 1 1 0 1 1 1 0 Androgen receptor SPACA7 PF15307.6 EGC33810.1 - 1.3 9.3 5.9 1 9.7 3.5 1.9 1 1 1 2 2 2 0 Sperm acrosome-associated protein 7 PA14 PF07691.12 EGC33811.1 - 8.4e-17 61.3 0.2 1.3e-16 60.7 0.2 1.2 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33811.1 - 0.0045 16.9 3.7 0.0045 16.9 3.7 11.1 10 1 1 11 11 11 3 Dictyostelium (slime mold) repeat CYTH PF01928.21 EGC33813.1 - 0.13 12.1 0.1 0.32 10.9 0.1 1.6 1 0 0 1 1 1 0 CYTH domain Mucin-like PF16058.5 EGC33813.1 - 1.8 8.7 80.8 1.5 8.9 31.5 3.2 1 1 0 2 2 2 0 Mucin-like FNIP PF05725.12 EGC33814.1 - 5.5e-66 218.5 28.6 3.4e-14 52.7 0.7 7.0 3 1 4 7 7 7 7 FNIP Repeat CDC48_2 PF02933.17 EGC33814.1 - 0.13 12.1 2.2 59 3.6 0.1 4.1 3 2 0 3 3 3 0 Cell division protein 48 (CDC48), domain 2 DUF1769 PF08588.10 EGC33814.1 - 0.24 11.6 12.5 29 5.0 0.0 6.3 5 2 4 9 9 9 0 Protein of unknown function (DUF1769) Mis12 PF05859.12 EGC33815.1 - 4.8e-18 65.5 0.2 4.8e-18 65.5 0.2 2.7 3 0 0 3 3 3 1 Mis12 protein DIT1_PvcA PF05141.12 EGC33815.1 - 0.85 9.0 16.5 0.013 15.0 9.1 1.7 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Pkinase PF00069.25 EGC33816.1 - 1.9e-74 250.4 0.0 2.3e-74 250.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33816.1 - 3.5e-41 141.2 0.0 4.7e-41 140.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC33816.1 - 7.4e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC33816.1 - 8.3e-05 21.7 0.2 0.0001 21.4 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGC33816.1 - 0.0053 15.6 0.0 0.0082 15.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase FTA2 PF13095.6 EGC33816.1 - 0.014 15.0 0.7 0.66 9.6 0.0 2.3 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGC33816.1 - 0.02 14.2 0.0 0.032 13.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.6 EGC33817.1 - 2.2e-29 101.6 0.9 3.8e-29 100.8 0.2 1.8 2 0 0 2 2 2 1 PH domain Herpes_LMP2 PF07415.11 EGC33817.1 - 0.0014 17.5 0.3 0.0018 17.2 0.3 1.1 1 0 0 1 1 1 1 Gammaherpesvirus latent membrane protein (LMP2) protein CsgF PF10614.9 EGC33817.1 - 0.38 11.0 4.1 0.38 11.0 3.0 1.4 1 1 0 1 1 1 0 Type VIII secretion system (T8SS), CsgF protein Gtr1_RagA PF04670.12 EGC33819.1 - 9.6e-73 244.4 3.8 1.3e-72 244.0 3.8 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.21 EGC33819.1 - 5.3e-07 29.2 0.0 9.5e-07 28.4 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC33819.1 - 1.8e-06 28.2 0.0 3.1e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC33819.1 - 3.5e-05 23.8 0.0 0.00019 21.5 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC33819.1 - 8.5e-05 22.1 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGC33819.1 - 0.00027 20.6 0.2 0.00039 20.1 0.2 1.2 1 0 0 1 1 1 1 Ras family Stirrup PF09061.6 EGC33819.1 - 0.0052 17.0 0.0 1.4 9.2 0.0 2.4 2 0 0 2 2 2 1 Stirrup Sp38 PF07354.12 EGC33819.1 - 0.19 11.1 1.4 3.1 7.2 0.2 2.3 2 0 0 2 2 2 0 Zona-pellucida-binding protein (Sp38) Pkinase PF00069.25 EGC33820.1 - 7.4e-23 81.2 0.5 1.8e-22 80.0 0.5 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC33820.1 - 7.9e-13 48.3 0.0 1.3e-12 47.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC33820.1 - 0.032 13.0 0.6 0.084 11.6 0.5 1.8 1 1 0 1 1 1 0 Fungal protein kinase EAV_GP5 PF15981.5 EGC33820.1 - 3.9 7.9 5.8 2.1 8.8 2.2 2.5 2 1 1 3 3 3 0 Envelope glycoprotein GP 5 of equine arteritis virus Presenilin PF01080.17 EGC33820.1 - 8.5 5.0 8.5 19 3.8 8.5 1.5 1 0 0 1 1 1 0 Presenilin TRM PF02005.16 EGC33821.1 - 5.7e-126 420.7 2.0 8.2e-126 420.2 2.0 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase zf_CCCH_4 PF18345.1 EGC33821.1 - 4e-05 23.5 0.8 9.3e-05 22.3 0.8 1.7 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGC33821.1 - 0.0063 16.3 0.4 0.013 15.3 0.4 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger Torus PF16131.5 EGC33821.1 - 0.0089 16.7 0.7 0.05 14.3 0.3 2.3 2 0 0 2 2 2 1 Torus domain Amino_oxidase PF01593.24 EGC33822.1 - 3.8e-44 151.7 0.0 5.1e-44 151.3 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC33822.1 - 7.2e-10 39.0 0.0 1.8e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGC33822.1 - 0.00017 20.9 0.3 0.00036 19.9 0.2 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.6 EGC33822.1 - 0.00053 19.3 1.0 0.00093 18.5 0.3 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.21 EGC33822.1 - 0.048 13.0 0.0 0.11 11.8 0.0 1.5 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pyr_redox_2 PF07992.14 EGC33822.1 - 0.052 12.8 0.0 0.12 11.6 0.0 1.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGC33822.1 - 0.13 11.0 0.1 0.22 10.2 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.24 EGC33822.1 - 0.21 10.6 0.2 0.35 9.9 0.2 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.24 EGC33823.1 - 1.8e-45 156.1 0.0 4.4e-43 148.2 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase DAO PF01266.24 EGC33823.1 - 1.2e-32 113.9 0.0 1.9e-30 106.6 0.0 2.4 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC33823.1 - 2.4e-17 62.9 0.1 1.6e-08 34.6 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.19 EGC33823.1 - 4.4e-10 39.3 0.3 0.00037 19.8 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.24 EGC33823.1 - 7.2e-10 38.5 0.7 4.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.6 EGC33823.1 - 8e-10 38.5 1.5 5.4e-05 22.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC33823.1 - 1.1e-08 34.7 0.2 2.3e-06 27.0 0.0 2.3 2 0 0 2 2 2 1 Thi4 family Pyr_redox_2 PF07992.14 EGC33823.1 - 2e-08 33.8 0.0 0.00052 19.3 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.14 EGC33823.1 - 2.4e-08 33.1 0.8 3.4e-05 22.7 0.1 2.4 2 0 0 2 2 2 2 HI0933-like protein FAD_oxidored PF12831.7 EGC33823.1 - 1.2e-06 28.2 0.2 5.2e-06 26.1 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox PF00070.27 EGC33823.1 - 2.5e-06 27.9 3.5 0.0032 18.0 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGC33823.1 - 5.7e-06 25.7 0.3 0.0027 16.9 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A AlaDh_PNT_C PF01262.21 EGC33823.1 - 0.00025 20.4 0.0 0.44 9.8 0.0 2.5 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain Lycopene_cycl PF05834.12 EGC33823.1 - 0.0064 15.6 0.1 0.063 12.3 0.1 2.2 2 0 0 2 2 2 1 Lycopene cyclase protein NAD_binding_7 PF13241.6 EGC33823.1 - 0.007 16.8 0.0 0.015 15.7 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding 3HCDH_N PF02737.18 EGC33823.1 - 0.014 15.3 1.0 0.37 10.7 0.1 2.2 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DHquinase_II PF01220.19 EGC33823.1 - 0.02 14.6 0.1 0.063 13.0 0.0 1.8 2 0 0 2 2 2 0 Dehydroquinase class II K_oxygenase PF13434.6 EGC33823.1 - 0.095 11.8 0.0 3.2 6.8 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) Trp_halogenase PF04820.14 EGC33823.1 - 0.19 10.5 1.5 0.74 8.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase FNIP PF05725.12 EGC33824.1 - 7.3e-77 253.3 35.4 1.1e-15 57.5 2.4 7.9 3 1 6 10 10 10 10 FNIP Repeat E3_UbLigase_R4 PF13764.6 EGC33825.1 - 0 1034.7 0.3 0 1034.7 0.3 2.9 3 0 0 3 3 3 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.17 EGC33825.1 - 4.3e-11 42.4 6.9 4.3e-11 42.4 6.9 3.9 3 0 0 3 3 3 2 Zinc finger, ZZ type UIM PF02809.20 EGC33825.1 - 0.034 14.1 2.5 0.27 11.2 0.0 3.0 2 0 0 2 2 2 0 Ubiquitin interaction motif Spindle_Spc25 PF08234.12 EGC33826.1 - 7.2e-22 77.4 1.0 3.1e-21 75.4 1.0 2.1 1 0 0 1 1 1 1 Chromosome segregation protein Spc25 DUF3870 PF12986.7 EGC33826.1 - 0.023 14.9 0.6 0.066 13.4 0.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) adh_short_C2 PF13561.6 EGC33827.1 - 1.7e-66 224.2 0.3 2.1e-66 223.8 0.3 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGC33827.1 - 7.7e-54 182.1 1.1 2.3e-53 180.6 0.7 1.7 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.10 EGC33827.1 - 9.4e-11 41.9 1.5 1.3e-10 41.5 0.6 1.7 2 1 0 2 2 2 1 KR domain DUF5353 PF17304.2 EGC33827.1 - 0.039 13.7 0.4 0.1 12.3 0.0 1.8 2 0 0 2 2 2 0 Family of unknown function (DUF5353) HlyD PF00529.20 EGC33827.1 - 0.16 11.9 0.1 0.44 10.5 0.1 1.8 1 1 0 1 1 1 0 HlyD membrane-fusion protein of T1SS FH2 PF02181.23 EGC33828.1 - 3.1e-84 283.2 14.1 3.1e-84 283.2 14.1 2.7 3 0 0 3 3 3 1 Formin Homology 2 Domain H-kinase_dim PF02895.14 EGC33828.1 - 0.031 14.7 0.2 4.7 7.7 0.0 3.9 3 1 0 3 3 3 0 Signal transducing histidine kinase, homodimeric domain DUF1848 PF08902.11 EGC33828.1 - 2.5 7.8 10.0 0.17 11.6 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1848) PRIMA1 PF16101.5 EGC33828.1 - 3.7 7.6 14.4 10 6.2 14.4 1.7 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 Solute_trans_a PF03619.16 EGC33829.1 - 1.6e-62 211.5 22.6 1.8e-53 181.7 15.8 2.1 1 1 1 2 2 2 2 Organic solute transporter Ostalpha BRCT PF00533.26 EGC33830.1 - 1.3e-09 38.3 2.2 3.7e-09 36.8 2.2 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC33830.1 - 5.1e-08 33.2 1.6 1.3e-07 31.9 1.6 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC33830.1 - 6.1e-05 22.9 0.1 0.00017 21.5 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain Glycos_transf_1 PF00534.20 EGC33831.1 - 3.3e-24 85.3 0.1 7.3e-24 84.2 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.26 EGC33831.1 - 5.4e-24 84.9 0.2 9.4e-23 80.9 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EGC33831.1 - 1.1e-18 68.0 0.0 1.8e-18 67.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 EGC33831.1 - 7.4e-09 35.5 0.9 2.9e-08 33.5 0.2 2.5 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EGC33831.1 - 9.5e-06 25.7 0.0 2.1e-05 24.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase like family 2 HALZ PF02183.18 EGC33831.1 - 0.034 14.4 7.5 0.048 13.9 0.6 2.8 2 0 0 2 2 2 0 Homeobox associated leucine zipper Glyco_trans_1_2 PF13524.6 EGC33831.1 - 0.095 13.1 0.0 0.31 11.5 0.0 1.9 1 1 0 1 1 1 0 Glycosyl transferases group 1 FtsH_ext PF06480.15 EGC33831.1 - 0.28 11.5 7.8 1.2 9.5 7.8 2.1 1 0 0 1 1 1 0 FtsH Extracellular HCO3_cotransp PF00955.21 EGC33831.1 - 3.3 6.4 7.9 6.1 5.5 7.9 1.3 1 0 0 1 1 1 0 HCO3- transporter family Shadoo PF14999.6 EGC33832.1 - 0.013 15.6 4.1 0.021 14.9 4.1 1.2 1 0 0 1 1 1 0 Shadow of prion protein, neuroprotective PfkB PF00294.24 EGC33833.1 - 2.8e-11 43.3 0.2 4.1e-10 39.4 0.1 2.5 2 1 1 3 3 3 1 pfkB family carbohydrate kinase zf-B_box PF00643.24 EGC33834.1 - 0.0067 16.5 7.6 0.016 15.4 7.6 1.6 1 0 0 1 1 1 1 B-box zinc finger DUF4665 PF15679.5 EGC33834.1 - 9.3 6.9 11.4 8.9 7.0 1.3 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4665) TPR_MLP1_2 PF07926.12 EGC33835.1 - 8.2e-05 22.7 15.7 8.2e-05 22.7 15.7 2.6 2 0 0 2 2 2 1 TPR/MLP1/MLP2-like protein Sec8_exocyst PF04048.14 EGC33835.1 - 0.0039 17.1 7.0 0.0039 17.1 7.0 2.4 2 1 0 2 2 2 1 Sec8 exocyst complex component specific domain DUF3958 PF13125.6 EGC33835.1 - 0.0079 16.4 11.9 0.0079 16.4 11.9 3.4 1 1 2 3 3 3 1 Protein of unknown function (DUF3958) XhlA PF10779.9 EGC33835.1 - 0.017 15.3 3.2 0.017 15.3 3.2 4.1 2 2 1 3 3 3 0 Haemolysin XhlA DUF4041 PF13250.6 EGC33835.1 - 0.05 13.5 1.8 0.24 11.3 0.1 2.8 2 2 0 2 2 2 0 Domain of unknown function (DUF4041) CENP-F_leu_zip PF10473.9 EGC33835.1 - 0.17 11.9 37.5 0.14 12.2 16.0 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF2937 PF11157.8 EGC33835.1 - 0.21 11.3 5.1 0.39 10.4 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2937) Filament PF00038.21 EGC33835.1 - 0.4 10.2 32.3 12 5.3 32.3 2.8 1 1 0 1 1 1 0 Intermediate filament protein GAS PF13851.6 EGC33835.1 - 0.52 9.6 37.6 1.7 8.0 19.3 2.3 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding DUF5486 PF17588.2 EGC33835.1 - 0.55 10.2 3.3 2.8 7.9 0.2 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5486) Fez1 PF06818.15 EGC33835.1 - 1 9.8 31.0 2.2 8.7 20.3 2.1 1 1 1 2 2 2 0 Fez1 Noelin-1 PF12308.8 EGC33835.1 - 2.1 8.4 14.0 0.059 13.4 4.9 2.8 1 1 3 4 4 4 0 Neurogenesis glycoprotein DUF1515 PF07439.11 EGC33835.1 - 2.5 8.2 7.1 13 5.9 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1515) ATG16 PF08614.11 EGC33835.1 - 3.5 7.8 30.3 0.2 11.8 12.4 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EGC33835.1 - 3.9 8.0 39.9 0.46 11.0 11.9 2.6 2 1 0 2 2 2 0 Apg6 coiled-coil region Fib_alpha PF08702.10 EGC33835.1 - 5.6 7.1 29.3 1 9.5 15.9 2.2 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family CENP-Q PF13094.6 EGC33835.1 - 6.2 7.0 27.0 0.62 10.2 8.0 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit YabA PF06156.13 EGC33835.1 - 9 7.0 26.7 0.74 10.5 6.4 3.1 1 1 1 2 2 2 0 Initiation control protein YabA EF1G PF00647.19 EGC33836.1 - 2.8e-43 146.3 0.1 4.7e-43 145.6 0.1 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.25 EGC33836.1 - 2.5e-07 30.8 2.6 4.8e-07 29.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC33836.1 - 0.00069 19.8 1.4 0.00079 19.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC33836.1 - 0.0056 16.7 0.0 0.012 15.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC33836.1 - 0.015 15.1 0.0 0.028 14.2 0.0 1.5 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain OAD_gamma PF04277.13 EGC33836.1 - 0.39 11.3 3.4 0.72 10.5 3.4 1.4 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain TIG PF01833.24 EGC33837.1 - 6.5e-23 80.6 13.4 5.9e-14 51.9 3.1 3.8 4 1 0 4 4 4 2 IPT/TIG domain FNIP PF05725.12 EGC33838.1 - 4.5e-57 190.0 69.6 1.5e-14 53.9 0.7 7.7 2 2 6 8 8 8 8 FNIP Repeat LRR_4 PF12799.7 EGC33838.1 - 0.26 11.8 20.6 1.1 9.8 0.7 5.0 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) Peptidase_S28 PF05577.12 EGC33840.1 - 7e-52 176.7 0.3 9.5e-52 176.2 0.3 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ribosomal_S9 PF00380.19 EGC33841.1 - 5.9e-34 117.2 0.1 9.9e-34 116.5 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 UPF0370 PF13980.6 EGC33842.1 - 0.067 13.2 0.0 0.076 13.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) V-SNARE PF05008.15 EGC33843.1 - 1.6e-14 54.0 4.1 1.6e-14 54.0 4.1 2.6 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGC33843.1 - 2.1e-10 40.7 5.8 2.1e-10 40.7 5.8 3.3 2 2 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGC33843.1 - 3.1e-05 23.8 0.4 3.1e-05 23.8 0.4 2.3 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.6 EGC33843.1 - 0.0003 20.3 4.5 0.00041 19.8 4.5 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) WEMBL PF05701.11 EGC33843.1 - 0.0022 16.8 2.5 0.003 16.4 2.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light T4SS PF07996.11 EGC33843.1 - 0.0051 17.2 13.1 0.013 15.9 13.1 1.6 1 1 0 1 1 1 1 Type IV secretion system proteins Fusion_gly PF00523.18 EGC33843.1 - 0.0078 14.5 1.5 0.01 14.1 0.2 1.8 1 1 0 1 1 1 1 Fusion glycoprotein F0 E2R135 PF11570.8 EGC33843.1 - 0.048 14.0 2.8 0.2 11.9 0.6 2.2 2 0 0 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 LRRC37AB_C PF14914.6 EGC33843.1 - 0.063 13.2 5.5 1.3 9.0 0.1 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain CENP-H PF05837.12 EGC33843.1 - 0.085 13.3 10.0 1.2 9.5 3.7 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) Arm-DNA-bind_2 PF12167.8 EGC33843.1 - 0.13 12.2 1.9 0.21 11.5 0.1 2.3 3 0 0 3 3 3 0 Arm DNA-binding domain Laminin_II PF06009.12 EGC33843.1 - 0.14 12.1 9.0 1.8 8.5 0.2 2.4 2 0 0 2 2 2 0 Laminin Domain II Strep_SA_rep PF06696.11 EGC33843.1 - 0.4 10.7 5.5 0.97 9.5 5.5 1.6 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF16 PF01519.16 EGC33843.1 - 0.44 11.1 13.8 0.3 11.6 5.4 2.4 2 1 0 2 2 2 0 Protein of unknown function DUF16 ArAE_1_C PF11728.8 EGC33843.1 - 0.91 9.5 10.6 2.6 8.0 9.3 2.3 1 1 2 3 3 3 0 Putative aromatic acid exporter C-terminal domain COG2 PF06148.11 EGC33843.1 - 1.5 8.9 6.3 4.2 7.5 0.0 2.7 2 2 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Cnn_1N PF07989.11 EGC33843.1 - 1.8 8.7 10.5 0.21 11.8 3.9 2.6 2 2 0 2 2 2 0 Centrosomin N-terminal motif 1 G8 PF10162.9 EGC33844.1 - 6e-27 94.2 0.1 2.7e-26 92.0 0.1 2.2 1 0 0 1 1 1 1 G8 domain Fibrinogen_aC PF12160.8 EGC33845.1 - 0.15 12.0 0.7 0.26 11.2 0.7 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain ubiquitin PF00240.23 EGC33846.1 - 4.3e-16 58.4 0.1 6.3e-16 57.9 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC33846.1 - 1.3e-05 24.9 0.1 2.3e-05 24.1 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3990 PF13151.6 EGC33846.1 - 0.0063 16.2 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) BPTA PF17044.5 EGC33846.1 - 0.033 14.1 0.2 0.073 12.9 0.0 1.6 2 0 0 2 2 2 0 Borrelial persistence in ticks protein A DUF5402 PF17393.2 EGC33846.1 - 0.087 12.8 0.0 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5402) AA_permease_2 PF13520.6 EGC33847.1 - 5.3e-50 170.5 46.3 6.9e-50 170.1 46.3 1.1 1 0 0 1 1 1 1 Amino acid permease DSPc PF00782.20 EGC33848.1 - 7.6e-25 87.3 0.2 3.5e-23 81.9 0.0 3.5 3 1 1 4 4 4 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.6 EGC33848.1 - 3.7e-08 33.6 3.3 3.7e-08 33.6 3.3 3.4 3 1 0 3 3 3 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.13 EGC33848.1 - 6.3e-05 22.6 4.2 0.0011 18.5 0.1 3.5 3 1 1 4 4 4 1 Tyrosine phosphatase family PASTA PF03793.19 EGC33848.1 - 0.023 14.5 3.3 0.14 12.0 2.2 2.6 2 0 0 2 2 2 0 PASTA domain Mucin PF01456.17 EGC33848.1 - 0.36 10.8 21.2 1.6 8.7 12.4 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Pinin_SDK_memA PF04696.13 EGC33848.1 - 1.8 8.6 45.7 1.3 9.0 13.7 3.6 3 0 0 3 3 3 0 pinin/SDK/memA/ protein conserved region SIR2_2 PF13289.6 EGC33849.1 - 6e-26 91.3 0.0 1.9e-25 89.6 0.0 1.9 1 0 0 1 1 1 1 SIR2-like domain Pyridoxal_deC PF00282.19 EGC33850.1 - 1.6e-16 60.1 0.0 8.3e-12 44.5 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain SR-25 PF10500.9 EGC33851.1 - 0.0014 18.2 5.5 0.0015 18.2 5.5 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein POT1PC PF16686.5 EGC33851.1 - 0.032 14.1 0.5 0.037 13.9 0.5 1.1 1 0 0 1 1 1 0 ssDNA-binding domain of telomere protection protein MCM PF00493.23 EGC33856.1 - 1.1e-66 224.2 0.1 2.2e-66 223.2 0.1 1.5 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGC33856.1 - 3.9e-23 81.7 0.3 1e-22 80.3 0.3 1.8 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGC33856.1 - 1.7e-06 27.6 0.0 0.00023 20.6 0.0 2.6 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC33856.1 - 9.7e-06 25.6 0.0 2.3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.29 EGC33856.1 - 0.00062 20.2 0.0 0.0016 18.9 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC33856.1 - 0.018 14.8 0.0 0.04 13.6 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.11 EGC33856.1 - 0.02 14.8 0.0 0.034 14.0 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGC33856.1 - 0.18 11.6 0.0 1.2 8.9 0.0 2.1 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain dUTPase PF00692.19 EGC33857.1 - 2.5e-35 121.0 0.0 2.8e-35 120.8 0.0 1.0 1 0 0 1 1 1 1 dUTPase POC3_POC4 PF10448.9 EGC33857.1 - 0.047 13.7 0.0 0.058 13.4 0.0 1.2 1 0 0 1 1 1 0 20S proteasome chaperone assembly proteins 3 and 4 zf-B_box PF00643.24 EGC33858.1 - 9.5e-10 38.5 20.9 8.3e-06 25.9 7.0 2.2 2 0 0 2 2 2 2 B-box zinc finger Sld5 PF05916.11 EGC33858.1 - 1.8e-07 31.6 0.0 3.5e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein IBR PF01485.21 EGC33858.1 - 0.0027 17.9 13.3 0.027 14.7 3.2 2.4 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain E7 PF00527.18 EGC33858.1 - 0.096 12.9 10.2 0.2 11.9 2.3 2.4 1 1 1 2 2 2 0 E7 protein, Early protein DHODB_Fe-S_bind PF10418.9 EGC33858.1 - 0.13 12.1 4.7 1.3 8.9 0.3 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Fer4_2 PF12797.7 EGC33858.1 - 0.23 11.6 11.7 1.5 9.0 2.3 2.5 2 0 0 2 2 2 0 4Fe-4S binding domain ZZ PF00569.17 EGC33858.1 - 1 9.2 16.8 0.93 9.4 1.1 4.1 2 2 2 4 4 4 0 Zinc finger, ZZ type zf-piccolo PF05715.13 EGC33858.1 - 3.2 8.0 16.8 1.8 8.8 5.7 2.4 1 1 1 2 2 2 0 Piccolo Zn-finger Fer2 PF00111.27 EGC33858.1 - 3.8 7.5 9.2 8.8 6.4 2.2 2.3 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain FNIP PF05725.12 EGC33859.1 - 2.2e-71 235.8 70.7 6.6e-18 64.6 3.7 8.9 5 3 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 EGC33859.1 - 0.0035 17.5 11.1 36 4.7 0.0 7.1 4 2 4 8 8 8 2 Protein of unknown function (DUF1769) FNIP PF05725.12 EGC33860.1 - 1.6e-33 114.6 14.6 8.1e-17 61.1 0.2 4.9 1 1 2 4 4 4 4 FNIP Repeat DUF1769 PF08588.10 EGC33860.1 - 0.02 15.1 2.8 53 4.1 0.0 4.1 2 2 2 4 4 4 0 Protein of unknown function (DUF1769) FNIP PF05725.12 EGC33861.1 - 2.3e-119 389.4 89.0 1.5e-15 57.1 0.1 14.6 7 4 6 15 15 15 14 FNIP Repeat Histone PF00125.24 EGC33862.1 - 3.4e-40 137.4 2.9 3.9e-40 137.3 2.9 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGC33862.1 - 4.3e-06 26.8 0.0 6.9e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC33862.1 - 1.7e-05 25.1 0.1 2.5e-05 24.6 0.1 1.2 1 0 0 1 1 1 1 CENP-S protein CBFD_NFYB_HMF PF00808.23 EGC33862.1 - 0.0019 18.4 0.5 0.0032 17.7 0.5 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID-31kDa PF02291.15 EGC33862.1 - 0.0053 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGC33862.1 - 0.012 15.6 0.1 0.018 15.1 0.1 1.3 1 0 0 1 1 1 0 Bromodomain associated PAF PF15715.5 EGC33862.1 - 0.041 14.5 2.8 0.05 14.2 2.5 1.4 1 1 0 1 1 1 0 PCNA-associated factor histone like domain TAF PF02969.17 EGC33862.1 - 0.12 12.6 0.1 0.21 11.8 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) FNIP PF05725.12 EGC33863.1 - 1.9e-34 117.5 32.1 9.2e-10 38.5 0.6 5.0 4 1 0 5 5 5 4 FNIP Repeat DUF1769 PF08588.10 EGC33863.1 - 0.0034 17.6 0.2 1 9.6 0.0 3.9 4 0 0 4 4 4 1 Protein of unknown function (DUF1769) RPA43_OB PF17875.1 EGC33863.1 - 0.025 15.2 0.8 50 4.5 0.0 3.1 2 1 1 3 3 3 0 RPA43 OB domain in RNA Pol I Ribosomal_L11_N PF03946.14 EGC33863.1 - 0.61 10.0 4.0 51 3.8 0.1 4.0 2 2 2 4 4 4 0 Ribosomal protein L11, N-terminal domain Thioredoxin PF00085.20 EGC33864.1 - 1.7e-19 69.7 0.0 2.1e-19 69.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.6 EGC33864.1 - 2.9e-07 30.3 0.0 3.6e-07 30.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGC33864.1 - 0.0019 18.5 0.0 0.0083 16.4 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGC33864.1 - 0.0091 16.4 0.1 0.057 13.9 0.1 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.10 EGC33864.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Redoxin OST3_OST6 PF04756.13 EGC33864.1 - 0.018 14.4 0.0 0.021 14.2 0.0 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGC33864.1 - 0.032 14.2 0.0 0.034 14.1 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family TraF PF13728.6 EGC33864.1 - 0.036 13.9 0.0 0.044 13.6 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Phlebovirus_G2 PF07245.11 EGC33865.1 - 0.024 13.2 0.1 0.032 12.7 0.1 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 FNIP PF05725.12 EGC33866.1 - 2.3e-38 130.1 19.9 1.3e-14 54.1 0.1 5.4 4 1 0 6 6 6 3 FNIP Repeat DUF1769 PF08588.10 EGC33866.1 - 0.011 15.9 3.9 37 4.6 0.0 4.7 3 2 2 5 5 5 0 Protein of unknown function (DUF1769) GAD PF02938.14 EGC33868.1 - 0.069 13.4 0.6 0.1 12.8 0.6 1.3 1 0 0 1 1 1 0 GAD domain TIR_3 PF18567.1 EGC33869.1 - 0.021 14.8 0.2 0.037 14.0 0.1 1.5 1 1 0 1 1 1 0 Toll/interleukin-1 receptor domain ComGF PF15980.5 EGC33869.1 - 1.2 9.6 15.3 0.11 12.9 8.8 2.4 1 1 1 2 2 2 0 Putative Competence protein ComGF DUF4153 PF13687.6 EGC33870.1 - 0.31 10.7 2.7 0.46 10.1 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4153) MCM PF00493.23 EGC33871.1 - 1.5e-21 76.5 0.5 1.7e-21 76.4 0.5 1.0 1 0 0 1 1 1 1 MCM P-loop domain MCM PF00493.23 EGC33872.1 - 3.5e-31 108.0 0.2 1.5e-29 102.7 0.2 2.2 1 1 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGC33872.1 - 1.7e-16 60.4 0.2 2.8e-16 59.7 0.2 1.3 1 0 0 1 1 1 1 MCM AAA-lid domain Mg_chelatase PF01078.21 EGC33872.1 - 1.5e-08 34.3 0.0 2.2e-07 30.5 0.0 2.0 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI GCIP PF13324.6 EGC33872.1 - 0.0094 15.6 0.0 0.029 14.0 0.0 1.7 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting AAA_3 PF07726.11 EGC33872.1 - 0.01 15.7 0.0 0.019 14.8 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC33872.1 - 0.041 13.9 0.0 0.078 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.26 EGC33872.1 - 0.073 12.8 0.0 0.098 12.4 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3330 PF11809.8 EGC33873.1 - 0.013 15.5 0.0 0.021 14.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) Acetyltransf_19 PF18015.1 EGC33873.1 - 0.036 14.3 1.1 0.043 14.0 1.1 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF5053 PF16476.5 EGC33873.1 - 0.077 12.7 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) DUF3861 PF12977.7 EGC33873.1 - 0.083 13.1 0.0 0.098 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) FNIP PF05725.12 EGC33874.1 - 2e-18 66.2 15.7 1.3e-10 41.2 2.7 3.2 2 1 1 3 3 3 3 FNIP Repeat Sld5 PF05916.11 EGC33875.1 - 1.6e-19 70.4 0.2 2.2e-19 69.9 0.2 1.2 1 0 0 1 1 1 1 GINS complex protein DUF1514 PF07438.11 EGC33875.1 - 0.044 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1514) Macoilin PF09726.9 EGC33876.1 - 0.055 12.0 20.5 0.062 11.9 20.5 1.0 1 0 0 1 1 1 0 Macoilin family Ndc1_Nup PF09531.10 EGC33876.1 - 8 5.0 7.2 11 4.6 7.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FNIP PF05725.12 EGC33877.1 - 1e-92 304.0 68.7 2e-16 59.9 1.3 7.7 4 2 5 9 9 9 9 FNIP Repeat Thymidylate_kin PF02223.17 EGC33878.1 - 1.6e-36 125.7 0.0 2.6e-35 121.8 0.0 1.9 1 1 1 2 2 2 1 Thymidylate kinase AAA_18 PF13238.6 EGC33878.1 - 0.068 13.7 0.0 0.094 13.3 0.0 1.4 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC33878.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase ATG16 PF08614.11 EGC33879.1 - 0.015 15.6 12.6 0.015 15.6 12.6 6.2 2 1 3 6 6 6 0 Autophagy protein 16 (ATG16) Integrase_H2C2 PF17921.1 EGC33882.1 - 7.8e-05 22.7 1.4 0.00014 21.9 0.3 2.0 2 0 0 2 2 2 1 Integrase zinc binding domain FNIP PF05725.12 EGC33883.1 - 8.5e-42 141.1 4.6 6.3e-17 61.5 0.1 3.0 1 1 1 3 3 3 3 FNIP Repeat DUF1769 PF08588.10 EGC33883.1 - 0.014 15.6 5.1 8.6 6.6 0.0 3.8 2 2 2 4 4 4 0 Protein of unknown function (DUF1769) DUF1359 PF07097.11 EGC33884.1 - 0.0052 17.0 4.2 0.17 12.1 0.4 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF1359) Activator-TraM PF11657.8 EGC33885.1 - 0.064 13.1 0.3 0.079 12.8 0.3 1.1 1 0 0 1 1 1 0 Transcriptional activator TraM DUF677 PF05055.12 EGC33886.1 - 0.056 12.3 0.0 0.064 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) Phi-29_GP4 PF05464.11 EGC33886.1 - 0.069 13.4 0.4 0.15 12.3 0.4 1.5 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Patatin PF01734.22 EGC33887.1 - 7.2e-08 32.8 0.3 7.2e-08 32.8 0.3 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase WW PF00397.26 EGC33887.1 - 2e-05 24.6 1.1 6.1e-05 23.0 1.1 1.9 1 0 0 1 1 1 1 WW domain Sugar_tr PF00083.24 EGC33888.1 - 6.5e-87 292.3 31.9 8.9e-87 291.8 31.9 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGC33888.1 - 2.7e-34 118.7 39.2 1.1e-25 90.3 19.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGC33888.1 - 6.2e-05 21.6 4.5 6.2e-05 21.6 4.5 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) Herpes_LMP1 PF05297.11 EGC33888.1 - 0.71 9.0 4.2 1.2 8.2 4.2 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) HABP4_PAI-RBP1 PF04774.15 EGC33889.1 - 0.00057 20.7 0.2 0.00063 20.6 0.2 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family Glyco_hydro_16 PF00722.21 EGC33891.1 - 3.7e-05 23.3 0.1 6.7e-05 22.4 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 DUF1180 PF06679.12 EGC33891.1 - 0.12 12.8 1.3 0.18 12.2 1.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_16 PF00722.21 EGC33892.1 - 2.6e-08 33.5 0.2 8.1e-08 31.9 0.2 1.9 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SOG2 PF10428.9 EGC33892.1 - 0.28 10.3 32.9 0.44 9.7 32.9 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EGC33892.1 - 8.9 4.8 36.3 18 3.9 36.3 1.4 1 0 0 1 1 1 0 Hamartin protein zf-RING_2 PF13639.6 EGC33893.1 - 7.4e-08 32.6 17.5 7.4e-08 32.6 17.5 1.7 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC33893.1 - 8.2e-06 25.6 15.6 1.8e-05 24.5 15.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC33893.1 - 9.2e-05 22.6 20.8 9.2e-05 22.6 20.8 2.1 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.6 EGC33893.1 - 9.3e-05 22.2 16.0 9.3e-05 22.2 16.0 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC33893.1 - 0.0002 21.1 12.2 0.00053 19.8 12.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC33893.1 - 0.00035 20.8 13.0 0.00035 20.8 13.0 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC33893.1 - 0.0011 18.8 20.4 0.0011 18.8 20.4 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33893.1 - 0.023 14.7 11.0 0.026 14.6 8.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_10 PF16685.5 EGC33893.1 - 0.048 13.8 9.4 0.15 12.2 9.4 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC33893.1 - 0.12 12.2 13.6 0.56 10.1 13.6 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGC33893.1 - 1.1 9.5 14.8 3.9 7.7 14.8 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC33893.1 - 1.7 8.8 15.6 0.072 13.2 8.7 2.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC33893.1 - 5 7.2 21.9 1.2 9.2 17.9 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGC33893.1 - 7.3 6.4 10.1 15 5.5 10.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger Ank_2 PF12796.7 EGC33894.1 - 0.0021 18.6 2.5 4.7 7.9 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) RPT PF13446.6 EGC33894.1 - 0.0081 16.1 0.2 0.027 14.4 0.2 1.9 1 0 0 1 1 1 1 A repeated domain in UCH-protein Ank_3 PF13606.6 EGC33894.1 - 0.0094 16.4 2.1 16 6.5 0.1 4.6 4 0 0 4 4 4 2 Ankyrin repeat FlaG PF03646.15 EGC33894.1 - 0.51 10.5 5.7 0.23 11.7 1.6 2.7 2 0 0 2 2 2 0 FlaG protein Peptidase_S28 PF05577.12 EGC33895.1 - 7.3e-117 390.8 4.5 8.2e-117 390.6 4.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.11 EGC33895.1 - 0.0059 15.3 0.1 0.01 14.6 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 RAC_head PF16717.5 EGC33896.1 - 0.56 11.2 2.4 0.82 10.7 0.5 2.3 2 0 0 2 2 2 0 Ribosome-associated complex head domain Topo_C_assoc PF14370.6 EGC33898.1 - 0.31 11.0 0.1 0.31 11.0 0.1 2.3 3 0 0 3 3 3 0 C-terminal topoisomerase domain T3SchapCesA PF11439.8 EGC33898.1 - 0.82 9.9 4.9 0.49 10.6 0.3 2.7 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF1493 PF07377.12 EGC33898.1 - 0.9 10.0 5.0 0.4 11.2 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1493) SnoaL_2 PF12680.7 EGC33899.1 - 4.4e-05 24.1 0.0 5.1e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC33899.1 - 0.0026 17.6 0.1 0.0091 15.8 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3271 PF11675.8 EGC33899.1 - 0.019 14.2 0.3 0.023 14.0 0.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DUF4440 PF14534.6 EGC33899.1 - 0.085 13.3 0.0 0.093 13.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SapB_2 PF03489.17 EGC33900.1 - 3.7e-08 33.3 0.1 8e-08 32.3 0.1 1.6 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC33900.1 - 0.0067 16.4 4.8 0.0067 16.4 4.8 3.3 5 0 0 5 5 5 1 Saposin-like type B, region 1 Mnd1 PF03962.15 EGC33900.1 - 0.075 13.3 0.4 0.16 12.2 0.2 1.7 2 0 0 2 2 2 0 Mnd1 HTH domain PA14 PF07691.12 EGC33901.1 - 1.1e-15 57.7 0.1 2.1e-15 56.8 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC33901.1 - 0.0041 17.0 6.0 0.0041 17.0 6.0 12.0 11 1 1 12 12 12 3 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC33902.1 - 1e-15 57.8 0.1 1.7e-15 57.1 0.1 1.3 1 0 0 1 1 1 1 PA14 domain YGGT PF02325.17 EGC33902.1 - 0.046 14.1 0.2 0.086 13.3 0.2 1.3 1 0 0 1 1 1 0 YGGT family Ank_5 PF13857.6 EGC33903.1 - 0.035 14.4 0.0 7.4 7.0 0.0 3.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC33903.1 - 0.044 14.4 2.5 7.9 7.1 0.0 4.6 4 1 1 5 5 5 0 Ankyrin repeats (3 copies) DUF727 PF05303.12 EGC33904.1 - 5.4e-27 93.9 0.1 6e-27 93.8 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF727) UPF0728 PF15092.6 EGC33904.1 - 0.13 12.1 0.0 0.23 11.3 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family UPF0728 HTH_Tnp_Tc5 PF03221.16 EGC33905.1 - 1.4e-15 57.0 0.5 3.2e-15 55.9 0.5 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BTB PF00651.31 EGC33906.1 - 2.2e-17 63.3 0.1 5.9e-17 61.9 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EGC33906.1 - 0.00017 21.6 0.9 0.0076 16.3 0.3 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch CFIA_Pcf11 PF11526.8 EGC33906.1 - 0.017 15.6 12.6 0.049 14.1 12.6 1.7 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Secretin_N_2 PF07655.13 EGC33906.1 - 1 9.9 20.3 3.1 8.4 20.3 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Orf78 PF06024.12 EGC33906.1 - 4.2 7.7 11.0 3.5 8.0 7.5 2.2 2 0 0 2 2 2 0 Orf78 (ac78) FNIP PF05725.12 EGC33907.1 - 3.3e-31 107.2 73.6 8.9e-08 32.2 1.5 13.1 6 3 8 14 14 14 12 FNIP Repeat GP67 PF17634.2 EGC33907.1 - 0.082 13.3 2.4 0.15 12.5 2.4 1.4 1 0 0 1 1 1 0 Gene product 67 ATG27 PF09451.10 EGC33908.1 - 1.9e-22 80.4 0.0 2.5e-22 80.0 0.0 1.0 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGC33908.1 - 1.1e-09 37.8 0.0 1.4e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor SUR7 PF06687.12 EGC33908.1 - 0.063 12.9 2.9 0.11 12.1 2.9 1.4 1 0 0 1 1 1 0 SUR7/PalI family ADH_zinc_N PF00107.26 EGC33909.1 - 1.5e-24 86.4 0.0 3.1e-24 85.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC33909.1 - 3.4e-07 30.1 0.0 3.6e-06 26.8 0.0 2.5 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.6 EGC33909.1 - 3.1e-05 25.0 0.0 7.5e-05 23.8 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGC33909.1 - 0.0018 17.6 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, C-terminal domain ADH_N_2 PF16884.5 EGC33909.1 - 0.011 15.7 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase TrkA_N PF02254.18 EGC33909.1 - 0.021 15.1 0.1 0.039 14.2 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain PALP PF00291.25 EGC33909.1 - 0.028 13.8 0.0 0.053 12.9 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme adh_short PF00106.25 EGC33909.1 - 0.036 13.5 0.1 0.06 12.8 0.1 1.3 1 0 0 1 1 1 0 short chain dehydrogenase DUF2855 PF11017.8 EGC33909.1 - 0.039 13.7 0.1 0.053 13.3 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) RHH_8 PF17723.1 EGC33909.1 - 0.13 12.4 0.0 0.27 11.4 0.0 1.5 1 0 0 1 1 1 0 Ribbon-Helix-Helix transcriptional regulator family Ras PF00071.22 EGC33910.1 - 2.9e-26 92.0 0.0 4.1e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33910.1 - 4.4e-12 46.3 0.0 1.5e-11 44.5 0.0 1.9 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC33910.1 - 1.5e-05 24.5 0.0 3.1e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC33910.1 - 0.0014 18.4 0.0 0.0029 17.4 0.0 1.5 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGC33910.1 - 0.021 14.7 1.5 1.2 9.0 0.0 2.8 2 1 1 3 3 3 0 RsgA GTPase Gtr1_RagA PF04670.12 EGC33910.1 - 0.023 14.1 0.0 0.032 13.6 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region ANTH PF07651.16 EGC33912.1 - 5.1e-45 153.6 0.0 5.1e-45 153.6 0.0 3.7 4 0 0 4 4 4 1 ANTH domain I_LWEQ PF01608.17 EGC33912.1 - 6.7e-45 153.1 11.4 6.7e-45 153.1 11.4 4.9 4 1 1 5 5 5 2 I/LWEQ domain ENTH PF01417.20 EGC33912.1 - 2.6e-06 27.5 0.4 3.3e-05 23.9 0.0 2.9 3 0 0 3 3 3 1 ENTH domain DUF2536 PF10750.9 EGC33912.1 - 0.02 14.8 1.0 0.077 12.9 1.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2536) Pox_A_type_inc PF04508.12 EGC33912.1 - 0.29 11.0 3.1 0.46 10.4 1.2 2.4 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat DUF4094 PF13334.6 EGC33913.1 - 0.0062 16.9 0.1 0.014 15.8 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) ABC2_membrane_3 PF12698.7 EGC33913.1 - 0.029 13.5 0.8 0.031 13.4 0.8 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein ArsP_1 PF03773.13 EGC33913.1 - 0.13 11.4 0.0 0.16 11.1 0.0 1.1 1 0 0 1 1 1 0 Predicted permease SAYSvFN PF10260.9 EGC33913.1 - 1.4 8.9 4.1 31 4.6 0.1 3.1 3 0 0 3 3 3 0 Uncharacterized conserved domain (SAYSvFN) FNIP PF05725.12 EGC33915.1 - 8.2e-61 201.9 19.8 6.3e-14 51.9 0.2 6.7 4 2 1 6 6 6 6 FNIP Repeat SSURE PF11966.8 EGC33915.1 - 1.1 9.1 5.6 49 3.8 0.0 4.5 1 1 5 6 6 6 0 Fibronectin-binding repeat EGF_2 PF07974.13 EGC33916.1 - 1.1e-08 35.3 29.4 0.00032 21.0 8.2 2.9 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.10 EGC33916.1 - 0.052 13.0 4.0 0.14 11.6 4.0 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3827 PF12877.7 EGC33916.1 - 0.13 10.6 1.9 0.21 9.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) EGF_Tenascin PF18720.1 EGC33916.1 - 0.69 10.0 18.0 0.38 10.9 4.6 2.7 2 0 0 2 2 2 0 Tenascin EGF domain EGF_alliinase PF04863.13 EGC33916.1 - 1.3 9.5 15.9 8.4 6.9 3.1 3.4 3 0 0 3 3 3 0 Alliinase EGF-like domain Laminin_EGF PF00053.24 EGC33916.1 - 1.3 9.2 22.0 4.8 7.4 6.2 2.7 2 0 0 2 2 2 0 Laminin EGF domain DUF1053 PF06327.14 EGC33917.1 - 4.3 7.9 7.7 9.2 6.9 4.6 2.8 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) Y_phosphatase2 PF03162.13 EGC33919.1 - 9.3e-43 145.7 0.0 1e-42 145.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGC33919.1 - 0.0036 17.3 0.0 0.0045 17.0 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGC33919.1 - 0.12 11.9 0.0 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase RlaP PF10127.9 EGC33920.1 - 1.8e-07 31.0 0.4 4.6e-07 29.7 0.0 1.8 2 0 0 2 2 2 1 RNA repair pathway DNA polymerase beta family EF-hand_1 PF00036.32 EGC33921.1 - 1.5e-10 39.9 2.0 0.0001 21.6 0.3 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGC33921.1 - 6.6e-08 32.9 0.2 1.2e-07 32.0 0.2 1.5 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC33921.1 - 3.2e-06 26.6 0.7 0.018 14.9 0.1 2.7 1 1 1 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGC33921.1 - 0.00021 20.6 0.4 0.13 11.8 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC33921.1 - 0.0071 16.2 0.4 0.028 14.3 0.3 2.1 1 1 1 2 2 2 1 EF-hand domain pair Dockerin_1 PF00404.18 EGC33921.1 - 0.095 12.9 0.2 0.48 10.6 0.3 2.1 2 1 0 2 2 2 0 Dockerin type I domain SWIRM PF04433.17 EGC33921.1 - 0.11 12.8 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 SWIRM domain ArfGap PF01412.18 EGC33922.1 - 2.3e-39 134.1 0.3 4.1e-39 133.3 0.3 1.4 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.29 EGC33922.1 - 6.3e-18 65.2 0.5 1.1e-17 64.4 0.5 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC33922.1 - 6.5e-06 26.5 5.2 8.3e-06 26.2 1.0 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.6 EGC33922.1 - 0.0014 18.7 0.3 0.0025 17.9 0.3 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.6 EGC33922.1 - 0.13 12.6 0.9 0.21 11.9 0.1 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Ras PF00071.22 EGC33923.1 - 5.9e-15 55.2 0.5 8.9e-15 54.7 0.5 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC33923.1 - 4.7e-08 33.3 0.6 1.2e-07 31.9 0.0 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGC33923.1 - 1.5e-07 31.4 1.5 0.0032 17.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC33923.1 - 0.0015 18.6 0.1 0.0033 17.5 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGC33923.1 - 0.012 15.9 0.0 0.024 15.0 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain NB-ARC PF00931.22 EGC33923.1 - 0.03 13.5 0.7 0.087 12.0 0.0 2.0 2 1 1 3 3 3 0 NB-ARC domain AAA PF00004.29 EGC33923.1 - 0.08 13.4 0.0 0.17 12.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNB PF00773.19 EGC33924.1 - 8.9e-25 87.7 0.1 8.9e-25 87.7 0.1 4.3 3 2 0 4 4 4 2 RNB domain LIN37 PF15306.6 EGC33924.1 - 0.29 11.3 9.9 0.07 13.4 5.7 2.1 2 0 0 2 2 2 0 LIN37 DUF1690 PF07956.11 EGC33924.1 - 1.2 9.5 14.6 0.061 13.8 5.0 3.3 3 1 0 3 3 3 0 Protein of Unknown function (DUF1690) Poxvirus_B22R_C PF13168.6 EGC33925.1 - 0.11 12.0 0.2 0.38 10.2 0.1 2.0 1 1 0 2 2 2 0 Poxvirus B22R protein C-terminal Syntaxin PF00804.25 EGC33925.1 - 0.73 9.5 11.4 0.027 14.1 4.9 1.9 2 1 0 2 2 2 0 Syntaxin B277 PF17623.2 EGC33925.1 - 1.4 7.9 7.9 0.049 12.7 1.9 1.6 2 0 0 2 2 2 0 Domain of unknown function PX PF00787.24 EGC33926.1 - 8.6e-16 57.9 1.9 1.5e-15 57.2 1.9 1.4 1 0 0 1 1 1 1 PX domain CppA_C PF14507.6 EGC33926.1 - 0.025 15.3 0.1 0.074 13.8 0.1 1.8 1 1 0 1 1 1 0 CppA C-terminal C2 PF00168.30 EGC33926.1 - 0.14 12.5 0.6 1.3 9.3 0.0 2.6 1 1 1 2 2 2 0 C2 domain HSP70 PF00012.20 EGC33927.1 - 2.2e-125 419.2 9.9 2.8e-125 418.8 9.9 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGC33927.1 - 4.7e-15 55.2 1.6 1.9e-14 53.3 1.3 1.8 2 0 0 2 2 2 1 MreB/Mbl protein PilM_2 PF11104.8 EGC33927.1 - 0.0012 18.0 2.1 0.3 10.1 0.0 2.4 2 1 0 2 2 2 2 Type IV pilus assembly protein PilM; CT_C_D PF02682.16 EGC33927.1 - 0.011 15.5 0.2 0.048 13.4 0.1 1.9 2 0 0 2 2 2 0 Carboxyltransferase domain, subdomain C and D TPP_enzyme_N PF02776.18 EGC33927.1 - 0.013 15.1 0.2 0.043 13.4 0.2 1.8 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain Dickkopf_N PF04706.12 EGC33928.1 - 5e-05 23.7 11.2 5e-05 23.7 11.2 7.2 4 2 1 5 5 5 2 Dickkopf N-terminal cysteine-rich region MSA-2c PF12238.8 EGC33928.1 - 0.89 9.5 9.1 0.085 12.9 4.6 1.6 2 0 0 2 2 2 0 Merozoite surface antigen 2c Glu_synthase PF01645.17 EGC33928.1 - 1.9 7.6 4.7 3.8 6.5 4.7 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase RINGv PF12906.7 EGC33929.1 - 1.3e-15 57.2 8.2 2.7e-15 56.2 8.2 1.6 1 0 0 1 1 1 1 RING-variant domain DDHD PF02862.17 EGC33929.1 - 0.00035 20.8 0.3 0.013 15.6 0.6 2.4 2 0 0 2 2 2 1 DDHD domain Flavi_M PF01004.19 EGC33929.1 - 0.031 14.0 0.0 0.13 12.1 0.0 2.0 1 0 0 1 1 1 0 Flavivirus envelope glycoprotein M GvpL_GvpF PF06386.11 EGC33929.1 - 0.047 13.6 6.5 0.079 12.9 6.5 1.3 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF zf-RING_2 PF13639.6 EGC33929.1 - 0.069 13.5 7.5 0.15 12.4 7.5 1.6 1 0 0 1 1 1 0 Ring finger domain Trypan_PARP PF05887.11 EGC33929.1 - 1.3 9.0 4.8 2.5 8.1 4.8 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.13 EGC33929.1 - 3.7 8.2 26.0 2.5 8.7 17.5 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2981 PF11200.8 EGC33929.1 - 4.7 6.9 13.6 7.4 6.2 9.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2981) LAP1C PF05609.12 EGC33929.1 - 7.4 5.5 17.9 21 4.0 14.3 2.1 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Ly49 PF08391.10 EGC33930.1 - 0.0086 16.4 0.1 0.0086 16.4 0.1 1.5 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region DUF3169 PF11368.8 EGC33930.1 - 0.034 13.6 0.6 0.051 13.1 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) DUF4834 PF16118.5 EGC33930.1 - 0.035 15.0 0.7 0.035 15.0 0.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) 7TM_GPCR_Sru PF10322.9 EGC33930.1 - 0.057 12.7 0.8 0.075 12.4 0.8 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru WBP-1 PF11669.8 EGC33930.1 - 0.1 13.3 0.1 0.18 12.4 0.1 1.4 1 0 0 1 1 1 0 WW domain-binding protein 1 NicO PF03824.16 EGC33930.1 - 0.19 11.0 0.6 1.8 7.8 0.0 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein Miga PF10265.9 EGC33930.1 - 0.2 10.6 6.9 0.25 10.3 6.9 1.1 1 0 0 1 1 1 0 Mitoguardin Inj_translocase PF16928.5 EGC33930.1 - 0.22 10.9 5.6 0.31 10.5 5.6 1.1 1 0 0 1 1 1 0 DNA/protein translocase of phage P22 injectosome Mcm10 PF09332.11 EGC33930.1 - 0.54 9.6 10.0 0.64 9.4 10.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor CytochromB561_N PF09786.9 EGC33930.1 - 0.6 9.0 20.5 0.69 8.8 20.5 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal DUF2489 PF10675.9 EGC33930.1 - 1.5 8.7 10.9 1 9.3 6.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) SPX PF03105.19 EGC33930.1 - 2 8.2 24.4 2.4 8.0 24.4 1.1 1 0 0 1 1 1 0 SPX domain Abhydrolase_9_N PF15420.6 EGC33932.1 - 0.22 11.5 5.2 0.59 10.1 4.0 2.0 1 1 1 2 2 2 0 Alpha/beta-hydrolase family N-terminus OAD_gamma PF04277.13 EGC33932.1 - 0.24 12.0 0.0 0.24 12.0 0.0 2.7 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1772 PF08592.11 EGC33932.1 - 0.81 10.0 9.9 2.1 8.7 1.9 3.4 2 1 2 4 4 4 0 Domain of unknown function (DUF1772) DUF4131 PF13567.6 EGC33932.1 - 0.83 9.3 7.9 0.56 9.9 2.0 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) DPM3 PF08285.11 EGC33932.1 - 6.6 7.0 10.8 15 5.9 3.9 3.2 2 1 1 3 3 3 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) WD40 PF00400.32 EGC33933.1 - 2.8e-22 78.6 0.7 0.001 19.9 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC33933.1 - 8.7e-17 61.2 0.0 5.5e-06 26.6 0.0 5.2 2 1 2 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC33933.1 - 3.1e-07 29.5 0.9 0.0003 19.6 0.1 3.0 1 1 1 3 3 3 2 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGC33933.1 - 1.7e-06 26.8 0.5 0.045 12.3 0.0 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGC33933.1 - 0.00021 21.2 0.1 0.56 10.1 0.1 3.2 1 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGC33933.1 - 0.00078 18.9 3.7 0.0077 15.6 0.2 2.9 3 1 0 3 3 3 1 WD40-like domain BBS2_Mid PF14783.6 EGC33933.1 - 0.0035 17.4 0.0 0.2 11.7 0.0 2.5 2 1 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Ge1_WD40 PF16529.5 EGC33933.1 - 0.028 13.4 0.1 3 6.7 0.0 3.2 2 1 1 3 3 3 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Coatomer_WDAD PF04053.14 EGC33933.1 - 0.048 12.7 0.5 0.29 10.1 0.1 2.1 1 1 2 3 3 3 0 Coatomer WD associated region Me-amine-dh_H PF06433.11 EGC33933.1 - 0.051 12.4 0.0 0.28 10.0 0.0 2.0 2 0 0 2 2 2 0 Methylamine dehydrogenase heavy chain (MADH) CsgG PF03783.14 EGC33933.1 - 0.1 11.9 0.1 0.17 11.2 0.1 1.3 1 0 0 1 1 1 0 Curli production assembly/transport component CsgG Ribonuclease_T2 PF00445.18 EGC33933.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 Ribonuclease T2 family Cortex-I_coil PF09304.10 EGC33934.1 - 3.6e-47 159.0 25.2 3.6e-47 159.0 25.2 3.2 1 1 2 3 3 3 1 Cortexillin I, coiled coil CH PF00307.31 EGC33934.1 - 2e-40 137.4 0.0 9.7e-19 67.6 0.1 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC33934.1 - 8.7e-06 25.5 0.0 0.21 11.4 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain FUSC PF04632.12 EGC33934.1 - 1.7 7.1 7.7 2.3 6.6 7.7 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF1664 PF07889.12 EGC33934.1 - 3.7 7.6 7.4 1.7 8.7 2.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Myosin_head PF00063.21 EGC33935.1 - 1e-236 787.4 17.6 8e-234 777.8 17.6 2.7 1 1 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.19 EGC33935.1 - 2.8e-23 82.2 1.3 1.6e-22 79.7 1.3 2.4 1 0 0 1 1 1 1 DIL domain IQ PF00612.27 EGC33935.1 - 1.3e-12 46.3 8.7 0.00036 20.1 0.7 5.2 5 0 0 5 5 5 2 IQ calmodulin-binding motif Myosin_N PF02736.19 EGC33935.1 - 8e-07 28.8 4.4 1.8e-06 27.7 4.4 1.6 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain AAA_22 PF13401.6 EGC33935.1 - 0.032 14.5 0.1 0.35 11.1 0.0 2.9 2 0 0 2 2 2 0 AAA domain DUF3541 PF12060.8 EGC33935.1 - 0.048 13.4 1.8 0.13 12.0 1.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3541) T2SSE PF00437.20 EGC33935.1 - 0.072 12.1 0.7 0.29 10.2 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein S1_2 PF13509.6 EGC33935.1 - 0.13 12.3 0.1 1.2 9.3 0.1 2.7 2 0 0 2 2 2 0 S1 domain AAA_16 PF13191.6 EGC33935.1 - 0.17 12.2 0.0 0.62 10.4 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain DUF1664 PF07889.12 EGC33935.1 - 7.6 6.6 16.3 0.8 9.8 4.8 4.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) PhyH PF05721.13 EGC33936.1 - 1.2e-15 58.4 0.0 2.1e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Phage_GPD PF05954.11 EGC33936.1 - 0.17 11.2 0.0 0.25 10.6 0.0 1.2 1 0 0 1 1 1 0 Phage late control gene D protein (GPD) IF-2B PF01008.17 EGC33937.1 - 3.5e-62 210.2 0.1 2.3e-60 204.2 0.1 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family 2-oxoacid_dh PF00198.23 EGC33937.1 - 0.041 13.3 0.1 0.096 12.1 0.1 1.6 1 1 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pantoate_ligase PF02569.15 EGC33938.1 - 2.3e-87 292.6 0.1 2.7e-87 292.3 0.1 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase CTP_transf_like PF01467.26 EGC33938.1 - 0.024 14.8 0.3 0.17 12.1 0.3 2.2 1 1 0 1 1 1 0 Cytidylyltransferase-like CdiI_2 PF18593.1 EGC33938.1 - 0.029 15.0 0.0 0.056 14.1 0.0 1.5 1 0 0 1 1 1 0 CdiI immunity protein EGF_2 PF07974.13 EGC33939.1 - 5e-13 49.2 45.0 2.1e-05 24.8 9.0 3.8 3 0 0 3 3 3 3 EGF-like domain TIG PF01833.24 EGC33939.1 - 3.7e-05 23.7 21.1 0.0018 18.3 1.3 4.7 5 1 1 6 6 6 2 IPT/TIG domain LRR_8 PF13855.6 EGC33939.1 - 0.0012 18.6 1.0 0.0045 16.7 1.0 2.0 1 0 0 1 1 1 1 Leucine rich repeat LRR_4 PF12799.7 EGC33939.1 - 0.0033 17.8 5.5 0.0044 17.4 2.3 3.0 3 0 0 3 3 3 1 Leucine Rich repeats (2 copies) hEGF PF12661.7 EGC33939.1 - 0.024 15.2 4.6 0.024 15.2 4.6 3.9 3 0 0 3 3 3 0 Human growth factor-like EGF EGF PF00008.27 EGC33939.1 - 0.033 14.5 32.8 0.074 13.4 6.4 3.8 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.24 EGC33939.1 - 0.11 12.6 36.5 0.31 11.2 6.2 3.7 2 1 1 3 3 3 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC33939.1 - 0.95 9.6 36.4 1.4 9.0 5.0 4.1 3 0 0 3 3 3 0 Tenascin EGF domain LRR_6 PF13516.6 EGC33939.1 - 1 9.6 4.8 16 5.8 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich repeat MMR_HSR1 PF01926.23 EGC33940.1 - 9.5e-05 22.5 0.0 0.0029 17.7 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC33940.1 - 0.034 13.6 0.0 0.072 12.5 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGC33940.1 - 0.046 13.6 0.0 0.089 12.7 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase Roc PF08477.13 EGC33940.1 - 0.047 13.9 0.1 1.1 9.5 0.0 2.9 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase GBP PF02263.19 EGC33940.1 - 0.072 12.3 0.0 0.13 11.5 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain PDEase_II PF02112.15 EGC33941.1 - 6.4e-101 337.8 0.4 8.8e-101 337.4 0.4 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II IBR PF01485.21 EGC33943.1 - 6e-14 52.0 31.0 1.4e-08 34.8 13.8 4.4 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-C3HC4_2 PF13923.6 EGC33943.1 - 0.00059 19.6 5.1 0.00059 19.6 5.1 4.7 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC33943.1 - 0.00074 19.3 5.0 0.00074 19.3 5.0 5.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) Arf PF00025.21 EGC33944.1 - 2.6e-59 199.6 0.0 3.4e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC33944.1 - 7.7e-15 55.2 0.0 1.3e-14 54.4 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC33944.1 - 4.6e-11 42.6 0.0 6.1e-11 42.2 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC33944.1 - 1e-10 41.4 0.0 1.8e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC33944.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGC33944.1 - 3e-07 30.0 5.6 0.00027 20.2 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGC33944.1 - 1e-05 25.5 0.0 2e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.14 EGC33944.1 - 0.011 15.6 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.12 EGC33944.1 - 0.016 15.1 0.9 2.5 8.0 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EGC33944.1 - 0.018 15.5 0.0 0.033 14.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC33944.1 - 0.018 15.3 0.2 0.19 12.0 0.2 2.1 1 1 0 1 1 1 0 AAA domain 6PF2K PF01591.18 EGC33944.1 - 0.026 13.8 0.0 0.046 13.0 0.0 1.5 1 0 0 1 1 1 0 6-phosphofructo-2-kinase SRP54 PF00448.22 EGC33944.1 - 0.028 14.0 0.5 0.073 12.7 0.4 1.7 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain ACT PF01842.25 EGC33944.1 - 0.11 12.3 0.0 5 7.0 0.0 2.2 2 0 0 2 2 2 0 ACT domain cobW PF02492.19 EGC33944.1 - 0.11 12.1 0.1 4.3 6.9 0.2 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Cofilin_ADF PF00241.20 EGC33945.1 - 2.6e-30 104.7 0.0 5.1e-19 68.3 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein VWA_2 PF13519.6 EGC33945.1 - 0.018 15.7 0.1 0.25 12.0 0.0 2.6 1 1 2 3 3 3 0 von Willebrand factor type A domain DUF2183 PF09949.9 EGC33945.1 - 0.089 13.1 0.1 1.5 9.2 0.0 2.8 2 1 2 4 4 4 0 Uncharacterized conserved protein (DUF2183) CsoSCA PF08936.10 EGC33945.1 - 0.09 11.4 0.0 0.19 10.4 0.0 1.5 1 0 0 1 1 1 0 Carboxysome Shell Carbonic Anhydrase DNA_pol3_a_NII PF11490.8 EGC33946.1 - 0.016 15.1 2.1 0.016 15.1 2.1 3.3 3 1 0 3 3 3 0 DNA polymerase III polC-type N-terminus II EutH PF04346.12 EGC33946.1 - 0.15 11.2 0.4 0.53 9.4 0.0 1.8 2 0 0 2 2 2 0 Ethanolamine utilisation protein, EutH PPR_3 PF13812.6 EGC33946.1 - 0.74 9.9 6.7 2.8 8.1 0.1 4.4 5 1 1 6 6 6 0 Pentatricopeptide repeat domain zf-C3HC4_2 PF13923.6 EGC33947.1 - 6.6e-11 41.9 9.0 1.1e-10 41.2 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC33947.1 - 5e-09 36.4 8.0 8.3e-09 35.7 8.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC33947.1 - 3.7e-08 33.1 10.0 9.8e-08 31.8 10.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC33947.1 - 1.4e-07 31.4 9.8 2.9e-07 30.3 9.8 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC33947.1 - 3.5e-07 30.0 7.6 5.8e-07 29.3 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC33947.1 - 7.6e-07 29.1 6.9 2.1e-06 27.7 6.9 1.8 1 0 0 1 1 1 1 RING-type zinc-finger BUD22 PF09073.10 EGC33947.1 - 2.1e-06 27.4 75.0 0.0012 18.3 43.9 2.4 2 0 0 2 2 2 2 BUD22 zf-rbx1 PF12678.7 EGC33947.1 - 1.3e-05 25.4 5.3 6.9e-05 23.1 5.3 2.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC33947.1 - 0.001 18.9 9.8 0.014 15.2 9.8 2.4 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC33947.1 - 0.003 17.7 6.5 0.0092 16.1 6.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.8 EGC33947.1 - 0.0037 17.1 6.6 0.0099 15.7 6.6 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_11 PF17123.5 EGC33947.1 - 0.013 15.2 4.7 0.028 14.1 4.7 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EGC33947.1 - 0.024 14.4 7.0 0.05 13.4 7.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC33947.1 - 0.031 14.3 1.4 0.061 13.4 1.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EGC33947.1 - 0.48 10.6 5.8 0.96 9.6 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 EGC33947.1 - 1.4 9.1 5.7 3.6 7.8 5.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF3439 PF11921.8 EGC33947.1 - 8.1 6.4 16.7 27 4.8 16.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Actin PF00022.19 EGC33948.1 - 9.7e-123 409.8 0.0 3.7e-122 407.9 0.0 1.7 1 1 0 1 1 1 1 Actin BUD22 PF09073.10 EGC33949.1 - 0.0035 16.7 15.0 0.0035 16.7 15.0 2.1 1 1 1 2 2 2 1 BUD22 dCMP_cyt_deam_1 PF00383.23 EGC33950.1 - 2.4e-18 65.9 0.2 2.9e-18 65.6 0.2 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.12 EGC33950.1 - 2.9e-08 34.0 0.1 4.6e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.6 EGC33950.1 - 0.059 13.0 1.6 0.38 10.3 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Pirin PF02678.16 EGC33951.1 - 5.6e-36 122.8 0.1 8.9e-36 122.2 0.1 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGC33951.1 - 1.7e-18 66.9 0.0 1.4e-17 64.0 0.0 2.4 2 1 0 2 2 2 1 Pirin C-terminal cupin domain KOW PF00467.29 EGC33951.1 - 0.21 11.6 2.0 0.62 10.1 2.0 1.8 1 0 0 1 1 1 0 KOW motif DUF3605 PF12239.8 EGC33953.1 - 1.3e-28 100.2 2.7 7.5e-28 97.8 2.7 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) Myb_DNA-bind_3 PF12776.7 EGC33953.1 - 0.66 11.0 5.0 13 6.8 1.1 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain UvrD_C PF13361.6 EGC33953.1 - 1.5 8.2 8.9 0.12 11.8 4.3 1.5 2 0 0 2 2 2 0 UvrD-like helicase C-terminal domain AAA_2 PF07724.14 EGC33954.1 - 6.4e-51 172.9 0.0 1.6e-49 168.3 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGC33954.1 - 2.1e-34 117.6 1.9 2.1e-34 117.6 1.9 2.3 1 1 1 2 2 2 1 AAA lid domain ClpB_D2-small PF10431.9 EGC33954.1 - 2.1e-26 91.7 0.2 8.2e-26 89.9 0.2 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.29 EGC33954.1 - 6.3e-23 81.7 0.5 1.6e-12 48.0 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC33954.1 - 1.8e-15 57.1 0.0 1.6e-09 37.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC33954.1 - 1.1e-09 38.9 7.1 2.9e-05 24.5 0.2 4.5 4 1 0 4 4 4 2 AAA ATPase domain AAA_22 PF13401.6 EGC33954.1 - 3.4e-07 30.6 9.6 0.0083 16.4 0.3 5.5 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.26 EGC33954.1 - 4.1e-07 29.8 0.0 0.00036 20.3 0.0 2.8 2 2 0 2 2 2 1 Sigma-54 interaction domain TniB PF05621.11 EGC33954.1 - 1.7e-06 27.6 0.0 0.0066 15.9 0.0 3.7 2 1 0 2 2 2 1 Bacterial TniB protein Mg_chelatase PF01078.21 EGC33954.1 - 2.6e-06 27.0 0.0 0.2 11.0 0.0 3.4 2 1 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_7 PF12775.7 EGC33954.1 - 1.3e-05 24.7 0.5 0.077 12.5 0.0 3.2 3 0 0 3 3 3 2 P-loop containing dynein motor region AAA_14 PF13173.6 EGC33954.1 - 2.8e-05 24.1 0.0 0.063 13.3 0.0 3.2 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGC33954.1 - 4.9e-05 23.1 0.0 0.099 12.4 0.0 2.7 2 0 0 2 2 2 2 IstB-like ATP binding protein RuvB_N PF05496.12 EGC33954.1 - 0.00022 21.0 2.1 0.47 10.2 0.0 3.7 3 1 0 3 3 2 1 Holliday junction DNA helicase RuvB P-loop domain Roc PF08477.13 EGC33954.1 - 0.00024 21.3 0.0 1.4 9.1 0.0 2.9 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RNA_helicase PF00910.22 EGC33954.1 - 0.00033 21.0 0.0 2.1 8.8 0.0 3.2 3 0 0 3 3 2 2 RNA helicase AAA_18 PF13238.6 EGC33954.1 - 0.00043 20.8 3.3 0.4 11.2 0.0 3.8 3 2 0 3 3 3 2 AAA domain TsaE PF02367.17 EGC33954.1 - 0.0011 19.0 0.0 1.8 8.6 0.0 2.6 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE RsgA_GTPase PF03193.16 EGC33954.1 - 0.0012 18.8 3.1 0.97 9.3 0.0 3.3 3 0 0 3 3 3 2 RsgA GTPase AAA_24 PF13479.6 EGC33954.1 - 0.0013 18.5 0.0 0.5 10.0 0.0 2.6 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGC33954.1 - 0.0014 18.5 0.1 0.26 11.2 0.0 3.0 3 0 0 3 3 2 1 NACHT domain AAA_28 PF13521.6 EGC33954.1 - 0.005 17.1 0.2 5.4 7.2 0.0 3.3 3 1 1 4 4 2 0 AAA domain AAA_30 PF13604.6 EGC33954.1 - 0.0075 16.0 0.7 8.3 6.1 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGC33954.1 - 0.0097 16.3 0.1 1.6 9.0 0.1 3.4 3 1 0 3 3 3 1 AAA domain AAA_33 PF13671.6 EGC33954.1 - 0.0099 16.0 0.0 6.4 6.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain SRP54 PF00448.22 EGC33954.1 - 0.011 15.3 0.5 2.9 7.5 0.0 3.7 4 0 0 4 4 4 0 SRP54-type protein, GTPase domain ATPase_2 PF01637.18 EGC33954.1 - 0.012 15.5 10.5 3.1 7.7 0.1 4.8 4 1 1 5 5 5 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EGC33954.1 - 0.012 15.5 0.0 11 5.9 0.0 3.2 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGC33954.1 - 0.015 14.4 0.0 0.94 8.6 0.1 3.1 2 1 0 2 2 2 0 Protein of unknown function (DUF815) ATP_bind_1 PF03029.17 EGC33954.1 - 0.017 14.9 0.0 0.86 9.3 0.0 2.7 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein ABC_tran PF00005.27 EGC33954.1 - 0.024 15.2 1.2 5.9 7.4 0.0 3.3 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.6 EGC33954.1 - 0.038 13.7 0.0 11 5.8 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_25 PF13481.6 EGC33954.1 - 0.081 12.5 0.3 2.9 7.4 0.0 3.2 4 0 0 4 4 4 0 AAA domain PduV-EutP PF10662.9 EGC33954.1 - 0.088 12.6 0.1 3 7.6 0.0 2.9 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation RRM_1 PF00076.22 EGC33955.1 - 2.3e-11 43.3 0.1 4.2e-11 42.5 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.25 EGC33956.1 - 3.2e-36 124.6 0.1 3.8e-36 124.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33956.1 - 2.2e-18 66.7 0.0 2.9e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33956.1 - 8.2e-08 32.4 0.0 1.3e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGC33957.1 - 2.4e-33 115.2 0.0 3.1e-33 114.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC33957.1 - 1.5e-14 54.1 0.0 2e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC33957.1 - 0.00012 22.0 0.0 0.00018 21.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC33957.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein SCAMP PF04144.13 EGC33958.1 - 1.4e-26 93.9 16.9 1.6e-26 93.6 16.9 1.1 1 0 0 1 1 1 1 SCAMP family Sensor PF13796.6 EGC33958.1 - 0.0054 16.8 4.6 0.97 9.5 1.7 2.6 2 1 0 2 2 2 2 Putative sensor MpPF26 PF07666.11 EGC33958.1 - 0.5 10.5 8.7 0.59 10.2 3.1 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 Hydrolase_4 PF12146.8 EGC33959.1 - 1.3e-18 67.1 0.0 2.8e-18 66.0 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC33959.1 - 5.6e-18 66.3 0.0 6.8e-18 66.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGC33959.1 - 1.8e-15 57.3 0.2 1.2e-14 54.6 0.2 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGC33959.1 - 2.8e-06 27.3 0.0 0.004 17.0 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DLH PF01738.18 EGC33959.1 - 4.7e-06 26.3 0.0 0.14 11.7 0.0 2.9 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_5 PF12695.7 EGC33959.1 - 0.00013 21.8 0.0 0.13 12.1 0.0 2.5 2 1 0 2 2 2 2 Alpha/beta hydrolase family DUF2048 PF09752.9 EGC33959.1 - 0.00025 20.3 0.0 0.17 11.0 0.0 2.2 2 0 0 2 2 2 2 Abhydrolase domain containing 18 FSH1 PF03959.13 EGC33959.1 - 0.001 18.8 0.0 0.019 14.6 0.0 2.5 2 1 0 2 2 2 1 Serine hydrolase (FSH1) DUF915 PF06028.11 EGC33959.1 - 0.0013 18.1 0.0 0.081 12.2 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.11 EGC33959.1 - 0.0025 17.8 0.0 0.087 12.7 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal UPF0227 PF05728.12 EGC33959.1 - 0.0084 16.1 0.0 0.9 9.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.20 EGC33959.1 - 0.012 15.3 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 0 Putative esterase Thioesterase PF00975.20 EGC33959.1 - 0.02 15.0 0.3 0.21 11.6 0.0 2.5 3 0 0 3 3 3 0 Thioesterase domain LIP PF03583.14 EGC33959.1 - 0.024 14.0 0.0 3.1 7.0 0.0 2.2 2 0 0 2 2 2 0 Secretory lipase Lipase_3 PF01764.25 EGC33959.1 - 0.025 14.5 0.0 0.06 13.2 0.0 1.6 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_4 PF08386.10 EGC33959.1 - 0.029 14.5 0.0 0.042 13.9 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.13 EGC33959.1 - 0.029 14.1 0.0 0.048 13.4 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein Ndr PF03096.14 EGC33959.1 - 0.048 12.3 0.0 0.091 11.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Peptidase_S9 PF00326.21 EGC33959.1 - 0.097 12.1 0.0 7.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase_phd PF10503.9 EGC33959.1 - 0.13 11.7 0.0 0.25 10.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase CTNNBL PF08216.11 EGC33961.1 - 1.1e-33 115.5 3.5 1.1e-33 115.5 3.5 3.0 2 1 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear WTX PF09422.10 EGC33961.1 - 0.19 10.8 0.4 0.3 10.1 0.4 1.2 1 0 0 1 1 1 0 WTX protein SUA5 PF03481.13 EGC33961.1 - 0.2 12.2 0.4 0.97 10.0 0.1 2.3 2 0 0 2 2 2 0 Putative GTP-binding controlling metal-binding NusB PF01029.18 EGC33961.1 - 2.6 8.3 7.2 0.4 10.9 0.6 3.0 3 0 0 3 3 3 0 NusB family Sdh5 PF03937.16 EGC33961.1 - 7.1 6.7 7.7 14 5.7 0.2 4.1 4 0 0 4 4 4 0 Flavinator of succinate dehydrogenase ArsA_ATPase PF02374.15 EGC33962.1 - 8.9e-106 353.5 0.1 1.1e-105 353.1 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.23 EGC33962.1 - 2.5e-11 43.7 0.1 5.8e-11 42.5 0.1 1.7 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGC33962.1 - 2.8e-11 43.7 0.0 5.9e-10 39.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain ParA PF10609.9 EGC33962.1 - 4e-06 26.4 0.6 0.0011 18.5 0.1 2.4 2 1 0 2 2 2 2 NUBPL iron-transfer P-loop NTPase CBP_BcsQ PF06564.12 EGC33962.1 - 2.7e-05 23.8 0.0 5.8e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsQ Fer4_NifH PF00142.18 EGC33962.1 - 7.1e-05 22.4 0.0 0.00013 21.5 0.0 1.5 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.22 EGC33962.1 - 0.0064 16.1 0.0 0.026 14.1 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.16 EGC33962.1 - 0.027 13.9 0.0 0.094 12.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.22 EGC33962.1 - 0.11 11.6 0.0 0.23 10.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain PH PF00169.29 EGC33963.1 - 2.3e-08 34.5 0.1 6.2e-08 33.1 0.1 1.8 1 0 0 1 1 1 1 PH domain TAP_C PF03943.13 EGC33963.1 - 0.00027 20.5 0.2 0.00096 18.7 0.0 2.1 2 0 0 2 2 2 1 TAP C-terminal domain PH_8 PF15409.6 EGC33963.1 - 0.00054 20.2 0.1 0.0015 18.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain LysM PF01476.20 EGC33963.1 - 0.00091 19.2 0.1 0.0037 17.3 0.1 2.1 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.6 EGC33963.1 - 0.004 17.0 0.0 0.011 15.5 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain 7tm_7 PF08395.12 EGC33963.1 - 0.044 13.0 4.4 0.053 12.7 1.5 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor Adaptin_binding PF10199.9 EGC33963.1 - 2 9.1 6.2 0.3 11.7 0.3 2.2 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 TFIIA PF03153.13 EGC33963.1 - 4.7 7.1 31.6 1 9.3 15.2 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF2222 PF09984.9 EGC33964.1 - 2.2 8.2 8.3 0.11 12.4 0.6 2.4 2 0 0 2 2 2 0 Uncharacterised signal transduction histidine kinase domain (DUF2222) Orthopox_A36R PF05950.11 EGC33966.1 - 0.0085 16.3 0.1 0.016 15.3 0.1 1.4 1 0 0 1 1 1 1 Orthopoxvirus A36R protein Mito_carr PF00153.27 EGC33967.1 - 3.6e-56 187.1 1.1 6.9e-25 86.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CTP_synth_N PF06418.14 EGC33967.1 - 0.11 11.8 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 CTP synthase N-terminus SF3A2 PF16835.5 EGC33968.1 - 8.2e-37 125.5 0.0 1.5e-36 124.7 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA-splicing factor SF3a complex subunit 2 (Prp11) zf-met PF12874.7 EGC33968.1 - 1.9e-06 28.1 0.9 3.3e-06 27.3 0.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type CactinC_cactus PF09732.9 EGC33968.1 - 3.3e-06 27.0 0.2 5.3e-06 26.4 0.2 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein PPR_3 PF13812.6 EGC33970.1 - 9.3e-08 32.0 2.2 4.6e-07 29.8 0.1 3.2 3 0 0 3 3 3 1 Pentatricopeptide repeat domain PPR PF01535.20 EGC33970.1 - 3.5e-06 26.9 9.2 0.08 13.2 0.0 5.8 7 0 0 7 7 7 2 PPR repeat PPR_2 PF13041.6 EGC33970.1 - 8.5e-06 25.9 10.0 0.0043 17.2 0.1 5.3 5 1 1 6 6 6 2 PPR repeat family PPR_1 PF12854.7 EGC33970.1 - 0.0039 16.8 0.0 6.2 6.6 0.0 3.9 4 0 0 4 4 4 1 PPR repeat OGFr_N PF04664.13 EGC33971.1 - 3.2e-47 160.8 9.7 7.5e-47 159.5 9.7 1.7 1 0 0 1 1 1 1 Opioid growth factor receptor (OGFr) conserved region Menin PF05053.13 EGC33971.1 - 0.1 11.0 6.4 0.14 10.5 6.4 1.3 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 EGC33971.1 - 0.36 11.4 12.8 0.85 10.2 12.8 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain Pox_Ag35 PF03286.14 EGC33971.1 - 1.8 8.3 7.5 3.6 7.3 7.5 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein HCO3_cotransp PF00955.21 EGC33971.1 - 3.4 6.4 6.1 4.6 5.9 6.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF1168 PF06658.12 EGC33971.1 - 8.6 6.2 13.3 17 5.2 13.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) Aldo_ket_red PF00248.21 EGC33972.1 - 4.5e-52 177.1 0.0 2.7e-50 171.2 0.0 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.22 EGC33973.1 - 1.6e-62 211.8 1.8 1.8e-62 211.6 1.8 1.1 1 0 0 1 1 1 1 Cytochrome P450 Y_Y_Y PF07495.13 EGC33973.1 - 0.012 15.5 0.1 0.029 14.3 0.1 1.6 1 0 0 1 1 1 0 Y_Y_Y domain MNE1 PF13762.6 EGC33973.1 - 3.7 7.5 8.9 3 7.8 4.6 2.3 2 0 0 2 2 2 0 Mitochondrial splicing apparatus component Ras PF00071.22 EGC33974.1 - 2.9e-40 137.5 1.6 2.5e-27 95.5 0.0 3.6 4 0 0 4 4 4 2 Ras family bMG10 PF17973.1 EGC33974.1 - 1.2e-26 93.4 0.0 4e-26 91.7 0.0 2.0 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain A2M_BRD PF07703.14 EGC33974.1 - 1e-12 48.6 1.1 5.2e-12 46.3 0.3 2.8 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain Roc PF08477.13 EGC33974.1 - 3.9e-12 46.4 0.0 0.00018 21.7 0.0 3.6 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase MG2 PF01835.19 EGC33974.1 - 4.1e-07 30.4 0.0 3.9e-06 27.2 0.0 2.9 3 0 0 3 3 3 1 MG2 domain A2M PF00207.22 EGC33974.1 - 1.4e-06 28.1 0.0 8e-06 25.6 0.0 2.4 2 0 0 2 2 2 1 Alpha-2-macroglobulin family UPF0669 PF17065.5 EGC33974.1 - 0.015 15.1 0.0 0.015 15.1 0.0 2.2 2 0 0 2 2 2 0 Putative cytokine, C6ORF120 MG4 PF17789.1 EGC33974.1 - 3.1 8.0 7.6 8.9 6.5 0.0 4.4 4 0 0 4 4 4 0 Macroglobulin domain MG4 CENP-L PF13092.6 EGC33975.1 - 1.8e-07 31.5 0.2 6.3e-07 29.8 0.2 1.8 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 PRC2_HTH_1 PF18118.1 EGC33975.1 - 0.094 13.5 1.4 0.25 12.2 1.4 1.7 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain CLTH PF10607.9 EGC33976.1 - 5.3e-34 117.2 3.2 9.3e-34 116.4 3.2 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.28 EGC33976.1 - 1.8e-27 95.8 0.1 2.9e-27 95.2 0.1 1.3 1 0 0 1 1 1 1 SPRY domain LisH PF08513.11 EGC33976.1 - 6.3e-05 22.8 0.1 0.00014 21.7 0.1 1.5 1 0 0 1 1 1 1 LisH Chorion_2 PF03964.15 EGC33976.1 - 0.27 12.1 5.8 0.58 11.0 5.8 1.4 1 0 0 1 1 1 0 Chorion family 2 SR-25 PF10500.9 EGC33976.1 - 2.5 7.6 19.0 4.4 6.9 19.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGAP PF00620.27 EGC33978.1 - 5.7e-30 104.1 0.0 2.3e-29 102.2 0.0 2.0 2 0 0 2 2 2 1 RhoGAP domain Cobl PF09469.10 EGC33978.1 - 0.018 15.3 0.0 3.3 8.0 0.0 2.7 2 0 0 2 2 2 0 Cordon-bleu ubiquitin-like domain RPEL PF02755.15 EGC33978.1 - 0.08 12.7 0.1 0.19 11.5 0.1 1.7 1 0 0 1 1 1 0 RPEL repeat Rad60-SLD PF11976.8 EGC33978.1 - 0.11 12.3 0.0 7.9 6.4 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Iso_dh PF00180.20 EGC33979.1 - 2.2e-88 296.7 0.5 2.6e-88 296.5 0.5 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Thioredoxin PF00085.20 EGC33980.1 - 1.8e-05 24.7 0.0 3.5e-05 23.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.16 EGC33980.1 - 0.00082 18.4 1.8 0.024 13.6 0.0 2.0 1 1 1 2 2 2 2 Phosducin SAM_1 PF00536.30 EGC33981.1 - 1.6e-07 31.7 1.0 2.2e-07 31.2 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC33981.1 - 0.002 18.0 0.0 0.0051 16.8 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain EGF_Tenascin PF18720.1 EGC33982.1 - 0.0033 17.4 3.8 0.0089 16.1 3.8 1.7 1 0 0 1 1 1 1 Tenascin EGF domain EGF_2 PF07974.13 EGC33982.1 - 0.0059 16.9 13.7 0.013 15.8 13.7 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGC33982.1 - 0.97 9.8 9.0 2.1 8.7 9.0 1.6 1 0 0 1 1 1 0 EGF-like domain DUF1744 PF08490.12 EGC33983.1 - 8.3e-112 373.7 2.8 1.6e-111 372.7 2.8 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.19 EGC33983.1 - 3.1e-69 233.7 14.0 4e-69 233.3 9.7 2.9 2 0 0 2 2 2 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.21 EGC33983.1 - 7.7e-14 51.3 9.7 2.8e-13 49.4 4.1 4.1 3 1 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.9 EGC33983.1 - 2.8e-09 37.0 0.2 6.8e-07 29.2 0.0 2.7 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB RNase_H_2 PF13482.6 EGC33983.1 - 2.6e-06 27.5 3.2 3.1e-05 24.0 0.0 4.1 4 1 0 4 4 4 1 RNase_H superfamily GDC-P PF02347.16 EGC33983.1 - 0.16 10.8 0.2 0.37 9.6 0.2 1.6 1 0 0 1 1 1 0 Glycine cleavage system P-protein DUF3886 PF13025.6 EGC33983.1 - 0.62 10.3 5.0 1.9 8.8 5.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3886) Cytochrome_C7 PF14522.6 EGC33983.1 - 1 9.4 13.6 0.77 9.8 7.9 2.7 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c UBA_2 PF08587.11 EGC33984.1 - 0.016 15.3 0.2 0.031 14.4 0.2 1.4 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) Dynamitin PF04912.14 EGC33984.1 - 0.055 12.8 0.0 0.065 12.6 0.0 1.0 1 0 0 1 1 1 0 Dynamitin Ad_cyc_g-alpha PF08509.11 EGC33984.1 - 0.14 11.9 0.0 0.46 10.3 0.1 1.7 2 0 0 2 2 2 0 Adenylate cyclase G-alpha binding domain AtuA PF07287.11 EGC33985.1 - 1.5e-107 359.4 0.0 2e-107 359.0 0.0 1.1 1 0 0 1 1 1 1 Acyclic terpene utilisation family protein AtuA 4_1_CTD PF05902.13 EGC33985.1 - 0.07 13.2 0.1 0.19 11.8 0.1 1.7 1 0 0 1 1 1 0 4.1 protein C-terminal domain (CTD) DinI PF06183.13 EGC33985.1 - 0.68 10.3 2.9 9.5 6.6 0.0 3.1 3 0 0 3 3 3 0 DinI-like family FAD_binding_3 PF01494.19 EGC33986.1 - 5.1e-14 52.3 0.0 3.8e-13 49.4 0.0 2.0 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGC33986.1 - 6.1e-05 22.2 0.0 0.0029 16.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase MFS_1 PF07690.16 EGC33987.1 - 7.1e-28 97.5 48.3 1.1e-20 73.9 29.9 1.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EGC33987.1 - 3.8e-22 78.7 22.0 4.3e-21 75.3 11.6 3.1 2 1 0 2 2 2 2 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.24 EGC33987.1 - 1.7e-06 27.2 5.6 1.7e-06 27.2 5.6 2.6 2 1 0 2 2 2 1 Sugar (and other) transporter SMC_N PF02463.19 EGC33988.1 - 2e-41 141.9 46.3 2.7e-40 138.1 46.3 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGC33988.1 - 2.2e-22 79.6 0.0 1.7e-21 76.7 0.0 2.5 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGC33988.1 - 6.2e-17 62.8 3.3 6.2e-17 62.8 3.3 7.2 3 2 4 7 7 7 1 AAA domain AAA_21 PF13304.6 EGC33988.1 - 9.2e-08 32.2 9.8 6.8e-06 26.1 0.3 5.4 3 3 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC33988.1 - 1.1e-06 28.3 0.0 2.3e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.6 EGC33988.1 - 6.6e-06 26.1 120.3 0.0002 21.2 59.5 4.2 3 1 0 3 3 3 2 AAA ATPase domain AAA PF00004.29 EGC33988.1 - 0.11 12.9 3.0 2.9 8.3 0.0 4.4 4 0 0 4 4 4 0 ATPase family associated with various cellular activities (AAA) MJ1316 PF04457.12 EGC33989.1 - 6.2e-09 36.5 2.6 1.5e-08 35.2 0.5 2.6 2 1 0 2 2 2 1 MJ1316 RNA cyclic group end recognition domain AP3D1 PF06375.11 EGC33989.1 - 0.17 12.1 12.7 0.39 10.9 12.7 1.6 1 1 0 1 1 1 0 AP-3 complex subunit delta-1 CDC45 PF02724.14 EGC33989.1 - 0.98 7.6 7.5 1.1 7.4 7.5 1.1 1 0 0 1 1 1 0 CDC45-like protein GAGA_bind PF06217.12 EGC33989.1 - 1.5 9.0 6.8 1.9 8.7 6.8 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family CemA PF03040.14 EGC33989.1 - 2.4 8.0 5.5 3.4 7.5 5.5 1.2 1 0 0 1 1 1 0 CemA family NmrA PF05368.13 EGC33990.1 - 1.5e-63 214.5 0.0 1.7e-63 214.3 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC33990.1 - 2.4e-15 56.9 0.0 3.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC33990.1 - 1.4e-06 27.6 0.0 2.3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGC33990.1 - 2.1e-05 24.8 0.0 3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGC33990.1 - 5.6e-05 22.7 0.1 0.00049 19.6 0.0 2.3 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGC33990.1 - 0.00038 20.4 0.0 0.0025 17.7 0.1 2.3 3 0 0 3 3 3 1 KR domain Semialdhyde_dh PF01118.24 EGC33990.1 - 0.094 13.2 0.0 0.19 12.2 0.0 1.5 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.20 EGC33990.1 - 0.17 12.0 0.4 0.36 11.0 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus ABC2_membrane_5 PF13346.6 EGC33990.1 - 0.18 11.4 0.0 0.29 10.6 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein NmrA PF05368.13 EGC33991.1 - 2.9e-64 216.8 0.0 3.4e-64 216.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC33991.1 - 2.3e-15 57.0 0.0 3.3e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC33991.1 - 1.4e-06 27.5 0.1 2.5e-06 26.7 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGC33991.1 - 3.8e-06 27.2 0.0 5.3e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGC33991.1 - 0.00012 21.7 0.1 0.00047 19.7 0.0 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGC33991.1 - 0.00013 21.9 0.0 0.001 19.0 0.0 2.1 2 0 0 2 2 2 1 KR domain Semialdhyde_dh PF01118.24 EGC33991.1 - 0.17 12.3 0.0 0.6 10.6 0.0 1.9 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain DnaJ_C PF01556.18 EGC33992.1 - 1e-43 148.9 1.6 1.4e-43 148.5 1.6 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGC33992.1 - 3.7e-28 97.4 1.1 6.7e-28 96.6 1.1 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGC33992.1 - 7.8e-16 58.2 18.4 1.4e-15 57.3 18.4 1.5 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGC33992.1 - 0.00015 21.7 9.1 0.045 13.7 1.5 2.6 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGC33992.1 - 0.0039 17.2 9.6 0.29 11.1 0.4 2.3 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF971 PF06155.12 EGC33992.1 - 0.052 14.2 2.7 11 6.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF971) zf-RING_10 PF16685.5 EGC33992.1 - 2.6 8.3 9.0 0.3 11.3 1.5 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 MFS_1 PF07690.16 EGC33993.1 - 4.1e-30 104.9 25.1 4.1e-30 104.9 25.1 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGC33993.1 - 1.9 6.8 10.4 0.035 12.5 0.7 2.1 2 0 0 2 2 2 0 Transmembrane secretion effector Metallophos PF00149.28 EGC33994.1 - 3.3e-33 115.9 0.1 4.6e-33 115.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC33994.1 - 0.18 12.0 0.0 0.29 11.3 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Njmu-R1 PF15053.6 EGC33995.1 - 8.4e-26 90.9 11.9 3.2e-22 79.1 11.1 3.0 2 1 0 2 2 2 2 Mjmu-R1-like protein family Zip PF02535.22 EGC33995.1 - 4.6 6.4 11.1 12 5.0 5.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter RF-1 PF00472.20 EGC33996.1 - 9.7e-39 131.9 5.6 1.5e-38 131.3 5.6 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.18 EGC33996.1 - 2.8e-31 108.9 1.7 5.3e-31 108.0 0.2 2.0 2 0 0 2 2 2 1 PCRF domain AbiEi_1 PF09407.10 EGC33996.1 - 0.1 12.9 0.0 0.15 12.4 0.0 1.3 1 0 0 1 1 1 0 AbiEi antitoxin C-terminal domain FNIP PF05725.12 EGC33998.1 - 2.8e-14 53.0 54.6 1.5e-05 25.0 3.2 9.0 6 3 3 9 9 9 7 FNIP Repeat DUF1387 PF07139.11 EGC33998.1 - 5.2 6.7 11.7 9.4 5.9 7.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1387) SNARE_assoc PF09335.11 EGC33999.1 - 6.4e-21 75.1 2.1 6.4e-21 75.1 2.1 2.2 1 1 1 2 2 2 1 SNARE associated Golgi protein GP41 PF00517.17 EGC33999.1 - 0.0015 18.5 3.3 0.0015 18.5 3.3 2.5 2 2 2 4 4 4 1 Retroviral envelope protein Connexin PF00029.19 EGC33999.1 - 0.22 11.3 3.7 0.39 10.4 0.4 2.2 2 0 0 2 2 2 0 Connexin DUF4337 PF14235.6 EGC33999.1 - 1.2 9.2 5.3 0.47 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF3292 PF11696.8 EGC33999.1 - 3.8 5.8 11.3 0.021 13.2 2.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3292) CSG2 PF16965.5 EGC33999.1 - 9.4 5.1 9.5 0.21 10.5 0.1 2.4 2 1 0 2 2 2 0 Ceramide synthase regulator DUF5134 PF17197.4 EGC34000.1 - 0.21 11.5 0.1 0.48 10.3 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5134) Cadherin_C_2 PF16492.5 EGC34000.1 - 1.9 9.3 4.5 2.4 9.0 0.3 2.6 2 1 0 2 2 2 0 Cadherin cytoplasmic C-terminal GSH_synth_ATP PF03917.17 EGC34001.1 - 9.4e-130 432.7 2.1 1.1e-129 432.5 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.15 EGC34001.1 - 2.8e-32 111.2 0.5 1.3e-31 109.1 0.0 2.4 3 0 0 3 3 3 1 Eukaryotic glutathione synthase PI-TkoII_IV PF18714.1 EGC34001.1 - 0.0043 16.5 0.5 0.025 14.1 0.1 2.2 1 1 1 2 2 2 1 DNA polymerase II intein Domain IV CBM49 PF09478.10 EGC34003.1 - 8.1e-19 67.7 0.6 1.1e-18 67.3 0.6 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 EpoR_lig-bind PF09067.10 EGC34004.1 - 0.0051 17.0 0.7 0.035 14.3 0.1 2.7 2 0 0 2 2 2 1 Erythropoietin receptor, ligand binding RWP-RK PF02042.15 EGC34005.1 - 9.1e-06 25.6 0.2 2e-05 24.5 0.2 1.6 1 0 0 1 1 1 1 RWP-RK domain PAP_assoc PF03828.19 EGC34007.1 - 2.5e-05 24.4 1.6 0.00028 21.1 1.8 2.1 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF2380 PF09533.10 EGC34008.1 - 5.5e-10 39.2 3.5 6.4e-10 39.0 3.5 1.1 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) WD40 PF00400.32 EGC34009.1 - 2.8e-19 69.1 12.5 8.2e-05 23.3 0.7 6.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34009.1 - 2.6e-12 46.8 5.7 0.00034 20.8 1.5 5.5 2 2 4 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EGC34009.1 - 0.0035 16.7 0.2 0.086 12.1 0.1 2.5 2 0 0 2 2 2 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Ge1_WD40 PF16529.5 EGC34011.1 - 2.7e-10 39.7 1.3 2.8e-06 26.5 0.0 2.8 2 0 0 2 2 2 2 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1132 PF06575.12 EGC34011.1 - 0.096 13.1 3.7 0.4 11.1 3.7 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Myosin_head PF00063.21 EGC34012.1 - 4.8e-274 910.7 4.5 5.9e-274 910.5 4.5 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC34012.1 - 1.5e-37 129.1 0.1 2.7e-37 128.3 0.1 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding IQ PF00612.27 EGC34012.1 - 8.5e-07 28.2 11.5 0.0011 18.6 0.6 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.6 EGC34012.1 - 0.00057 20.2 0.0 0.062 13.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.6 EGC34012.1 - 0.0062 16.9 0.0 0.021 15.2 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGC34012.1 - 0.023 14.6 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 RsgA GTPase Zeta_toxin PF06414.12 EGC34012.1 - 0.029 13.6 0.0 0.089 12.1 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin DUF2075 PF09848.9 EGC34012.1 - 0.047 12.9 1.8 0.48 9.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) PRK PF00485.18 EGC34012.1 - 0.073 12.8 0.0 0.61 9.8 0.0 2.3 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGC34012.1 - 0.09 13.3 0.0 0.29 11.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGC34012.1 - 0.11 12.5 0.0 0.34 10.9 0.0 1.8 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Gtr1_RagA PF04670.12 EGC34013.1 - 3.3e-103 344.0 2.3 4e-103 343.7 2.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.22 EGC34013.1 - 5.6e-10 39.0 0.0 1.2e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34013.1 - 6.3e-10 39.3 0.2 2e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC34013.1 - 1.7e-07 31.3 0.0 4e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Arf PF00025.21 EGC34013.1 - 2e-07 30.7 0.1 3e-07 30.1 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC34013.1 - 0.063 13.0 0.1 0.31 10.8 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation PI3_PI4_kinase PF00454.27 EGC34014.1 - 8.4e-06 25.8 0.9 0.003 17.4 0.4 2.6 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Ank_2 PF12796.7 EGC34014.1 - 3.6e-05 24.3 0.0 0.00012 22.6 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC34014.1 - 0.00045 20.5 0.4 0.006 17.0 0.1 3.0 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGC34014.1 - 0.0021 18.6 0.3 0.0072 16.9 0.1 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Tna_leader PF08053.11 EGC34014.1 - 0.021 14.8 0.9 0.1 12.6 0.9 2.3 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Ank_5 PF13857.6 EGC34014.1 - 0.079 13.3 0.1 0.46 10.9 0.1 2.3 2 0 0 2 2 2 0 Ankyrin repeats (many copies) EAL PF00563.20 EGC34015.1 - 0.021 14.4 0.2 0.049 13.2 0.0 1.7 2 0 0 2 2 2 0 EAL domain bZIP_1 PF00170.21 EGC34016.1 - 1.2e-08 34.9 6.8 1.2e-08 34.9 6.8 3.4 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.15 EGC34016.1 - 8.1e-06 25.8 9.1 8.1e-06 25.8 9.1 5.2 4 1 0 4 4 4 1 Basic region leucine zipper DUF3437 PF11919.8 EGC34016.1 - 0.37 10.7 4.6 1.5 8.8 2.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) Arfaptin PF06456.13 EGC34017.1 - 0.0061 16.2 0.3 0.0081 15.7 0.3 1.2 1 0 0 1 1 1 1 Arfaptin-like domain BD_b_sandwich PF18820.1 EGC34019.1 - 0.091 12.8 0.6 16 5.5 0.0 2.6 2 0 0 2 2 2 0 Bdellovibrio Beta-sandwich FHA PF00498.26 EGC34019.1 - 0.43 11.0 6.6 0.92 9.9 0.0 3.4 4 0 0 4 4 4 0 FHA domain EGF_2 PF07974.13 EGC34019.1 - 3.2 8.2 13.3 0.28 11.6 8.4 1.8 2 0 0 2 2 2 0 EGF-like domain TMPIT PF07851.13 EGC34020.1 - 1e-112 376.6 10.8 1.4e-112 376.2 10.8 1.1 1 0 0 1 1 1 1 TMPIT-like protein DUF4686 PF15742.5 EGC34020.1 - 0.0082 15.3 12.3 0.0082 15.3 12.3 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) UPF0184 PF03670.13 EGC34020.1 - 0.031 14.7 0.9 0.031 14.7 0.9 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Laminin_II PF06009.12 EGC34020.1 - 0.28 11.2 13.5 0.42 10.6 13.5 1.2 1 0 0 1 1 1 0 Laminin Domain II Spc7 PF08317.11 EGC34020.1 - 2.5 6.9 18.4 0.34 9.7 14.6 1.4 2 0 0 2 2 2 0 Spc7 kinetochore protein Myosin_head PF00063.21 EGC34021.1 - 2.5e-292 971.2 4.1 2.5e-292 971.2 4.1 2.9 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_tail_1 PF01576.19 EGC34021.1 - 3.1e-75 253.8 354.2 7.1e-45 153.3 177.5 3.8 1 1 2 3 3 3 3 Myosin tail Filament PF00038.21 EGC34021.1 - 8.4e-12 45.3 302.0 5.3e-05 22.9 20.4 10.4 1 1 9 10 10 10 8 Intermediate filament protein Myosin_N PF02736.19 EGC34021.1 - 5.3e-10 39.0 0.1 1.7e-09 37.3 0.1 2.0 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain Cortex-I_coil PF09304.10 EGC34021.1 - 0.00083 19.5 17.2 0.00083 19.5 17.2 16.3 3 2 15 18 18 18 2 Cortexillin I, coiled coil DUF5082 PF16888.5 EGC34021.1 - 0.00096 19.4 14.6 0.00096 19.4 14.6 13.7 1 1 12 14 14 14 1 Domain of unknown function (DUF5082) IQ PF00612.27 EGC34021.1 - 0.013 15.3 3.4 0.018 14.8 0.4 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif HpaP PF09483.10 EGC34021.1 - 0.057 13.7 2.2 0.44 10.8 0.4 3.6 2 0 0 2 2 2 0 Type III secretion protein (HpaP) AAA_22 PF13401.6 EGC34021.1 - 0.19 12.0 0.0 0.19 12.0 0.0 7.0 7 1 0 7 7 7 0 AAA domain AAA_16 PF13191.6 EGC34021.1 - 0.28 11.6 0.0 0.28 11.6 0.0 6.5 5 2 0 5 5 5 0 AAA ATPase domain DUF773 PF05600.12 EGC34022.1 - 7.8e-97 325.1 44.6 3.3e-89 300.0 37.8 2.0 1 1 1 2 2 2 2 CDK5 regulatory subunit-associated protein 3 SlyX PF04102.12 EGC34022.1 - 0.27 11.9 3.6 0.48 11.1 0.6 2.8 1 1 1 2 2 2 0 SlyX DUF4535 PF15054.6 EGC34022.1 - 2.1 8.1 8.0 0.43 10.4 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4535) MFS_1 PF07690.16 EGC34024.1 - 5.8e-39 134.0 13.5 2.2e-37 128.8 9.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC34024.1 - 3.3e-09 36.1 11.6 5e-09 35.5 11.6 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EGC34024.1 - 0.00025 19.5 0.0 0.00025 19.5 0.0 3.6 3 2 0 4 4 4 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.13 EGC34024.1 - 0.0028 16.1 7.4 0.097 11.0 0.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Zip PF02535.22 EGC34024.1 - 0.0061 15.8 9.3 0.099 11.8 0.0 3.2 3 1 0 3 3 3 2 ZIP Zinc transporter HNOBA PF07701.14 EGC34024.1 - 0.04 13.3 0.1 0.04 13.3 0.1 1.7 2 0 0 2 2 2 0 Heme NO binding associated DUF3439 PF11921.8 EGC34024.1 - 1.9 8.5 5.6 4.4 7.3 5.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MGC-24 PF05283.11 EGC34024.1 - 3.4 8.1 15.4 6.2 7.3 5.2 3.2 2 1 1 3 3 3 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EGC34024.1 - 9 6.3 13.4 0.41 10.6 7.2 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein P_C10 PF14974.6 EGC34025.1 - 0.14 12.3 0.0 0.58 10.3 0.0 2.0 2 0 0 2 2 2 0 Protein C10 CBS PF00571.28 EGC34026.1 - 1.3e-13 51.1 0.3 2.6e-10 40.6 0.0 2.4 2 0 0 2 2 2 2 CBS domain HTH_29 PF13551.6 EGC34026.1 - 0.18 11.8 0.0 0.99 9.5 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix TT_ORF1 PF02956.14 EGC34026.1 - 6.9 5.2 10.6 8.5 4.9 10.6 1.1 1 0 0 1 1 1 0 TT viral orf 1 RRM_1 PF00076.22 EGC34027.1 - 7.1e-33 112.3 1.2 8.1e-16 57.6 0.1 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC34027.1 - 1.3e-09 37.9 0.0 0.0016 18.4 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGC34027.1 - 1.5e-06 27.9 0.0 0.0018 18.1 0.0 2.3 2 1 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGC34027.1 - 0.00023 21.2 0.0 0.073 13.2 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif SpoVG PF04026.12 EGC34027.1 - 0.015 15.4 0.0 0.42 10.8 0.0 2.4 2 0 0 2 2 2 0 SpoVG PHM7_cyt PF14703.6 EGC34027.1 - 0.12 12.6 1.6 53 4.0 0.0 3.1 2 2 1 3 3 3 0 Cytosolic domain of 10TM putative phosphate transporter NGF PF00243.18 EGC34028.1 - 0.002 18.3 0.7 0.0023 18.2 0.7 1.2 1 0 0 1 1 1 1 Nerve growth factor family APG17 PF04108.12 EGC34028.1 - 0.066 12.3 2.3 0.068 12.3 2.3 1.1 1 0 0 1 1 1 0 Autophagy protein Apg17 Nop PF01798.18 EGC34028.1 - 0.74 9.2 4.1 0.31 10.5 0.3 1.8 1 1 1 2 2 2 0 snoRNA binding domain, fibrillarin RCC1 PF00415.18 EGC34029.1 - 1.5e-64 214.4 19.9 3.6e-14 53.1 0.2 7.3 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.25 EGC34029.1 - 3.6e-51 174.5 4.8 1.2e-50 172.8 4.8 2.0 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.25 EGC34029.1 - 4.7e-36 124.5 2.3 2.6e-35 122.1 0.0 3.1 3 0 0 3 3 3 1 Protein kinase domain RCC1_2 PF13540.6 EGC34029.1 - 6e-26 89.7 29.2 1.7e-07 30.8 0.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat Pkinase_Tyr PF07714.17 EGC34029.1 - 1.5e-25 90.0 0.0 3.6e-25 88.7 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC34029.1 - 0.01 15.2 0.0 0.023 14.1 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC34029.1 - 0.013 15.4 0.0 0.026 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Endonuclease_5 PF04493.14 EGC34030.1 - 1.3e-51 175.1 0.0 1.9e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Endonuclease V UvrC_HhH_N PF08459.11 EGC34030.1 - 0.00013 21.9 0.1 0.00051 20.0 0.0 2.0 2 0 0 2 2 2 1 UvrC Helix-hairpin-helix N-terminal Metallophos PF00149.28 EGC34031.1 - 1.4e-40 140.0 0.1 1.7e-40 139.7 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGC34031.1 - 4.8e-16 58.9 0.7 9.3e-16 58.0 0.3 1.7 2 0 0 2 2 2 1 Serine-threonine protein phosphatase N-terminal domain SRP54 PF00448.22 EGC34032.1 - 1.2e-73 246.9 1.2 1.9e-73 246.3 1.2 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.19 EGC34032.1 - 1.1e-23 83.7 0.4 1.1e-23 83.7 0.4 3.2 2 1 0 2 2 1 1 Signal peptide binding domain SRP54_N PF02881.19 EGC34032.1 - 3.3e-13 49.7 7.4 3.6e-13 49.5 4.3 2.5 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.19 EGC34032.1 - 5.9e-06 26.0 0.9 9.3e-05 22.1 0.9 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.10 EGC34032.1 - 8.4e-06 25.3 0.4 0.014 14.9 0.1 2.7 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_17 PF13207.6 EGC34032.1 - 0.00034 21.0 0.2 0.00034 21.0 0.2 2.2 3 0 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.23 EGC34032.1 - 0.00069 19.7 0.5 0.0034 17.4 0.5 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.6 EGC34032.1 - 0.00085 19.7 0.0 0.0025 18.2 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGC34032.1 - 0.00092 19.4 0.0 0.0018 18.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC34032.1 - 0.0018 18.0 0.2 0.0076 16.0 0.1 2.0 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGC34032.1 - 0.0039 17.3 0.1 0.024 14.7 0.0 2.4 2 1 0 2 2 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain MeaB PF03308.16 EGC34032.1 - 0.0067 15.4 0.0 0.015 14.3 0.0 1.5 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB MobB PF03205.14 EGC34032.1 - 0.029 14.3 0.2 0.082 12.8 0.2 1.9 1 1 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA PF00004.29 EGC34032.1 - 0.03 14.8 2.4 0.35 11.3 0.4 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.20 EGC34032.1 - 0.065 13.1 0.0 0.12 12.3 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase ResIII PF04851.15 EGC34032.1 - 0.067 13.2 0.3 0.25 11.4 0.3 2.1 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit CLP1_P PF16575.5 EGC34032.1 - 0.12 12.1 0.4 2.1 8.1 0.1 2.2 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_28 PF13521.6 EGC34032.1 - 0.16 12.2 0.2 0.38 11.0 0.2 1.7 1 1 0 1 1 1 0 AAA domain DUF4226 PF10774.9 EGC34032.1 - 0.18 12.1 0.1 0.48 10.7 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) AAA_25 PF13481.6 EGC34032.1 - 0.21 11.1 0.0 0.5 9.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain L_biotic_typeA PF04604.13 EGC34032.1 - 6.4 6.7 5.9 29 4.6 1.7 3.1 3 0 0 3 3 3 0 Type-A lantibiotic BsuBI_PstI_RE PF06616.11 EGC34033.1 - 0.0052 16.1 0.3 0.0065 15.8 0.3 1.2 1 0 0 1 1 1 1 BsuBI/PstI restriction endonuclease domain FNIP PF05725.12 EGC34034.1 - 1.3e-220 713.5 43.0 1.4e-15 57.1 0.5 14.4 3 2 8 17 17 17 17 FNIP Repeat Phage_min_tail PF05939.13 EGC34034.1 - 2.7e-09 37.4 0.3 49 4.4 0.0 11.0 5 3 7 13 13 13 1 Phage minor tail protein Peptidase_C21 PF05381.12 EGC34034.1 - 0.25 11.7 28.1 1.9 8.9 1.0 7.1 2 2 7 9 9 9 0 Tymovirus endopeptidase zf-RVT PF13966.6 EGC34035.1 - 0.00012 22.7 2.6 0.00012 22.7 0.8 2.0 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase GATA PF00320.27 EGC34035.1 - 0.0028 17.2 0.0 0.0067 16.0 0.0 1.6 1 0 0 1 1 1 1 GATA zinc finger Pyr_redox_2 PF07992.14 EGC34035.1 - 0.038 13.2 0.0 0.077 12.2 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Cullin_Nedd8 PF10557.9 EGC34035.1 - 1.2 9.2 4.9 4.8 7.3 0.1 3.5 3 0 0 3 3 3 0 Cullin protein neddylation domain FNIP PF05725.12 EGC34037.1 - 1.5e-196 636.5 65.6 7.8e-16 58.0 0.7 16.2 13 2 2 16 16 16 16 FNIP Repeat DUF3692 PF12469.8 EGC34037.1 - 0.25 11.5 1.1 22 5.3 0.0 4.4 4 2 0 4 4 4 0 CRISPR-associated protein Pyr_redox_2 PF07992.14 EGC34038.1 - 8.7e-17 61.3 0.0 1e-15 57.8 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGC34038.1 - 3.3e-05 23.9 0.0 0.045 13.7 0.0 2.3 2 0 0 2 2 2 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.12 EGC34038.1 - 0.00045 19.4 0.0 0.014 14.5 0.0 2.1 1 1 1 2 2 2 1 Lycopene cyclase protein DAO PF01266.24 EGC34038.1 - 0.00069 19.3 0.0 0.01 15.5 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGC34038.1 - 0.0042 16.4 1.5 4.4 6.5 0.1 3.0 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.14 EGC34038.1 - 0.0053 15.7 0.3 0.055 12.3 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox PF00070.27 EGC34038.1 - 0.0078 16.8 0.4 0.25 11.9 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC34038.1 - 0.022 15.0 0.0 0.055 13.7 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGC34038.1 - 0.076 11.7 0.0 0.2 10.3 0.0 1.7 1 1 0 1 1 1 0 HI0933-like protein K_oxygenase PF13434.6 EGC34038.1 - 0.16 11.1 0.1 0.97 8.5 0.0 2.0 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) TPR_12 PF13424.6 EGC34039.1 - 6.6e-11 42.4 12.2 0.05 13.9 0.1 6.5 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34039.1 - 0.0002 21.3 22.6 0.76 10.2 0.4 7.5 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC34039.1 - 0.052 13.6 4.6 29 5.0 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC34039.1 - 0.26 11.5 32.6 8.8 6.7 0.1 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC34039.1 - 0.26 11.2 31.8 1 9.3 0.0 8.1 9 0 0 9 9 9 0 Tetratricopeptide repeat DUF1462 PF07315.11 EGC34039.1 - 0.61 10.4 3.2 0.75 10.1 0.3 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1462) TPR_6 PF13174.6 EGC34039.1 - 3.3 8.6 12.4 23 5.9 0.1 5.4 5 0 0 5 5 5 0 Tetratricopeptide repeat MFS_1 PF07690.16 EGC34040.1 - 2.7e-49 168.0 27.8 2.7e-49 168.0 27.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC34040.1 - 6.9e-07 28.5 25.2 4.3e-05 22.6 13.5 2.4 2 1 0 2 2 2 2 Sugar (and other) transporter MFS_4 PF06779.14 EGC34040.1 - 8.8e-07 28.5 2.9 8.8e-07 28.5 2.9 2.2 2 0 0 2 2 2 1 Uncharacterised MFS-type transporter YbfB OATP PF03137.20 EGC34040.1 - 0.013 13.8 11.7 0.06 11.6 2.6 3.1 2 1 0 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family EGF_2 PF07974.13 EGC34041.1 - 0.0011 19.3 12.2 0.0025 18.2 12.2 1.7 1 0 0 1 1 1 1 EGF-like domain EGF PF00008.27 EGC34041.1 - 0.053 13.8 5.8 0.16 12.3 5.8 1.8 1 0 0 1 1 1 0 EGF-like domain DUF1180 PF06679.12 EGC34041.1 - 0.11 12.9 0.0 0.19 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Laminin_EGF PF00053.24 EGC34041.1 - 0.11 12.6 7.5 0.034 14.3 4.2 1.8 2 0 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 EGC34041.1 - 0.18 12.5 5.4 0.54 11.0 4.6 2.3 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGC34041.1 - 0.58 10.3 5.6 2 8.6 5.6 1.9 1 0 0 1 1 1 0 Tenascin EGF domain Wx5_PLAF3D7 PF09688.10 EGC34041.1 - 4.5 7.3 6.5 0.26 11.3 0.1 2.1 3 0 0 3 3 3 0 Protein of unknown function (Wx5_PLAF3D7) EF-hand_1 PF00036.32 EGC34042.1 - 0.071 12.7 0.1 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EGC34042.1 - 0.16 11.9 0.2 2.2 8.4 0.1 2.3 2 0 0 2 2 2 0 EF-hand domain Gelsolin PF00626.22 EGC34043.1 - 8.2e-77 253.1 9.8 1.5e-15 56.8 0.0 6.6 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.19 EGC34043.1 - 3.1e-10 39.9 0.2 8.4e-10 38.6 0.2 1.8 1 0 0 1 1 1 1 Villin headpiece domain PAC4 PF16093.5 EGC34043.1 - 0.019 15.2 8.2 0.57 10.4 0.0 4.1 4 0 0 4 4 4 0 Proteasome assembly chaperone 4 CutA1 PF03091.15 EGC34043.1 - 5.6 6.9 5.1 34 4.4 0.0 3.9 5 0 0 5 5 5 0 CutA1 divalent ion tolerance protein Lactamase_B_2 PF12706.7 EGC34044.1 - 6.4e-10 38.9 0.0 1.5e-09 37.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGC34044.1 - 0.0036 17.3 0.0 0.0068 16.4 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily DUF3053 PF11254.8 EGC34044.1 - 0.072 12.7 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) G-alpha PF00503.20 EGC34045.1 - 1.1e-89 301.1 8.3 1.3e-89 300.9 8.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC34045.1 - 1.4e-12 47.4 2.3 1.6e-08 34.2 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC34045.1 - 0.0031 17.7 0.3 1.6 8.9 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Sigma54_activat PF00158.26 EGC34045.1 - 0.0032 17.2 0.0 0.26 11.0 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain GTP_EFTU PF00009.27 EGC34045.1 - 0.005 16.4 0.1 0.15 11.6 0.1 2.4 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP-synt_F6 PF05511.11 EGC34046.1 - 0.071 13.5 0.1 0.17 12.3 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 PilP PF04351.13 EGC34046.1 - 0.16 11.9 0.5 0.52 10.3 0.6 1.8 2 0 0 2 2 2 0 Pilus assembly protein, PilP zf-His_Me_endon PF05551.11 EGC34047.1 - 0.00095 19.4 1.0 0.0028 17.8 1.0 1.8 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease Otopetrin PF03189.13 EGC34047.1 - 0.012 14.4 2.0 0.016 14.0 2.0 1.2 1 0 0 1 1 1 0 Otopetrin Autophagy_N PF03986.13 EGC34048.1 - 1.3e-41 141.7 10.1 6.2e-41 139.6 10.1 1.9 1 1 0 1 1 1 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.15 EGC34048.1 - 1e-22 80.5 0.6 2.3e-22 79.3 0.6 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_C PF10381.9 EGC34048.1 - 3e-13 49.0 3.9 3e-13 49.0 3.9 1.7 2 0 0 2 2 2 1 Autophagocytosis associated protein C-terminal RRN3 PF05327.11 EGC34048.1 - 0.31 9.6 4.9 0.37 9.3 4.9 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SDA1 PF05285.12 EGC34048.1 - 9.6 5.5 20.9 25 4.1 19.6 2.0 1 1 1 2 2 2 0 SDA1 FH2 PF02181.23 EGC34049.1 - 9.2e-73 245.5 2.0 9.2e-73 245.5 2.0 4.1 4 0 0 4 4 4 1 Formin Homology 2 Domain Methyltransf_32 PF13679.6 EGC34049.1 - 8.1e-25 87.7 4.0 8.1e-25 87.7 4.0 3.1 2 1 0 2 2 2 1 Methyltransferase domain DUF3361 PF11841.8 EGC34049.1 - 2.9e-10 40.3 0.8 1.6e-09 37.9 0.2 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3361) Taxilin PF09728.9 EGC34049.1 - 0.00018 20.8 0.7 0.00018 20.8 0.7 5.0 5 0 0 5 5 5 1 Myosin-like coiled-coil protein Methyltransf_25 PF13649.6 EGC34049.1 - 0.0064 17.2 0.0 0.022 15.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC34049.1 - 0.0075 17.0 0.1 0.04 14.6 0.1 2.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34049.1 - 0.082 12.7 0.0 0.33 10.8 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2c PF01411.19 EGC34051.1 - 5.7e-171 569.8 0.2 7.8e-171 569.3 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.14 EGC34051.1 - 5.5e-18 64.8 0.5 1.5e-17 63.4 0.5 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Chisel PF15355.6 EGC34051.1 - 0.094 13.0 0.1 7.2 6.9 0.0 2.5 2 0 0 2 2 2 0 Stretch-responsive small skeletal muscle X protein, Chisel PAP_assoc PF03828.19 EGC34052.1 - 3.8e-05 23.8 1.1 0.00036 20.7 1.2 2.2 2 0 0 2 2 2 1 Cid1 family poly A polymerase Peptidase_M76 PF09768.9 EGC34052.1 - 0.052 13.3 0.0 0.072 12.9 0.0 1.2 1 0 0 1 1 1 0 Peptidase M76 family Elicitin PF00964.17 EGC34052.1 - 0.066 13.3 0.5 0.12 12.4 0.5 1.4 1 0 0 1 1 1 0 Elicitin DUF2380 PF09533.10 EGC34053.1 - 7.8e-16 58.2 4.6 9e-16 58.0 4.6 1.1 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) DDE_3 PF13358.6 EGC34055.1 - 1.1e-07 31.8 0.1 1.3e-07 31.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Nucleolin_bd PF16725.5 EGC34055.1 - 0.093 12.4 0.4 0.28 10.8 0.1 1.8 2 0 0 2 2 2 0 Nucleolin binding domain Y_phosphatase3 PF13350.6 EGC34056.1 - 0.0012 18.9 0.0 0.013 15.5 0.0 2.6 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGC34056.1 - 3.4 7.5 0.0 3.4 7.5 0.0 5.3 4 2 1 5 5 5 0 Dual specificity phosphatase, catalytic domain Holin_BhlA PF10960.8 EGC34057.1 - 0.35 10.9 2.6 0.89 9.6 2.6 1.6 1 0 0 1 1 1 0 BhlA holin family DUF647 PF04884.14 EGC34058.1 - 2.4e-98 328.6 0.9 3.2e-98 328.2 0.9 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Presenilin PF01080.17 EGC34058.1 - 5 5.8 14.8 9.9 4.8 14.8 1.5 1 0 0 1 1 1 0 Presenilin Piwi PF02171.17 EGC34059.1 - 7.9e-74 248.6 0.2 3.7e-73 246.4 0.0 1.9 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.22 EGC34059.1 - 4e-23 81.7 1.3 4e-23 81.7 1.3 1.9 2 0 0 2 2 2 1 PAZ domain ArgoL1 PF08699.10 EGC34059.1 - 0.00014 21.5 0.0 0.00032 20.3 0.0 1.7 1 0 0 1 1 1 1 Argonaute linker 1 domain ArgoN PF16486.5 EGC34059.1 - 0.011 16.3 0.0 0.034 14.8 0.0 1.9 1 0 0 1 1 1 0 N-terminal domain of argonaute TFIIA PF03153.13 EGC34059.1 - 0.085 12.8 14.0 0.15 12.1 14.0 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AhpC-TSA PF00578.21 EGC34060.1 - 1.1e-39 135.2 0.0 1.3e-39 134.9 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC34060.1 - 2.7e-28 98.5 0.0 3.2e-28 98.3 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGC34060.1 - 8.2e-06 26.1 0.0 1.2e-05 25.5 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 EGC34060.1 - 0.0015 18.6 0.0 0.0024 18.0 0.0 1.4 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.12 EGC34060.1 - 0.033 13.7 0.0 0.036 13.6 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF899) FNIP PF05725.12 EGC34061.1 - 2.3e-19 69.3 63.4 3e-06 27.3 0.5 12.4 7 3 7 15 15 15 12 FNIP Repeat DUF4366 PF14283.6 EGC34062.1 - 0.62 10.1 4.4 7.6 6.6 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4366) zf-CCHC PF00098.23 EGC34064.1 - 4.1e-06 26.6 1.3 6.4e-06 26.0 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1825 PF08855.10 EGC34064.1 - 0.013 15.4 1.1 0.1 12.5 0.0 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF1825) zf-CCHC_5 PF14787.6 EGC34064.1 - 0.091 12.5 0.8 0.22 11.3 0.3 1.8 2 0 0 2 2 2 0 GAG-polyprotein viral zinc-finger zf-CCHC_3 PF13917.6 EGC34064.1 - 0.15 12.1 1.4 0.28 11.2 1.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Macoilin PF09726.9 EGC34064.1 - 0.36 9.3 25.8 0.063 11.8 21.2 1.8 2 0 0 2 2 2 0 Macoilin family DDDD PF10161.9 EGC34065.1 - 9.1e-05 22.1 2.9 73 3.2 0.0 7.3 9 0 0 9 9 9 4 Putative mitochondrial precursor protein RRS1 PF04939.12 EGC34066.1 - 4.9e-52 176.1 8.0 4.9e-52 176.1 8.0 2.0 2 1 1 3 3 3 1 Ribosome biogenesis regulatory protein (RRS1) RRM_1 PF00076.22 EGC34067.1 - 7.1e-62 205.2 5.0 8.3e-20 70.4 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC34067.1 - 2.2e-10 40.2 0.7 0.0035 16.9 0.1 3.4 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC34067.1 - 1.1e-07 31.8 0.1 0.26 11.4 0.0 4.0 3 0 0 3 3 3 2 RNA recognition motif BRAP2 PF07576.12 EGC34067.1 - 1.7e-06 28.1 0.5 0.053 13.7 0.0 3.4 3 0 0 3 3 3 2 BRCA1-associated protein 2 RRM_occluded PF16842.5 EGC34067.1 - 3e-06 27.0 0.0 0.0073 16.1 0.0 3.5 3 0 0 3 3 3 1 Occluded RNA-recognition motif RNA_bind PF08675.11 EGC34067.1 - 0.01 15.8 0.1 0.66 10.0 0.0 3.5 3 0 0 3 3 3 0 RNA binding domain SET_assoc PF11767.8 EGC34067.1 - 0.17 11.6 0.6 17 5.1 0.1 3.4 3 0 0 3 3 3 0 Histone lysine methyltransferase SET associated Dynamitin PF04912.14 EGC34068.1 - 5.8e-106 355.1 31.1 6.7e-106 354.9 31.1 1.0 1 0 0 1 1 1 1 Dynamitin FlaC_arch PF05377.11 EGC34068.1 - 0.0051 17.2 22.1 0.63 10.5 2.1 5.6 4 2 0 4 4 4 3 Flagella accessory protein C (FlaC) EMC3_TMCO1 PF01956.16 EGC34068.1 - 0.029 14.1 0.5 0.11 12.2 0.0 2.3 2 2 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like Peroxin-13_N PF04088.13 EGC34068.1 - 0.036 14.3 0.6 0.036 14.3 0.6 2.6 3 0 0 3 3 3 0 Peroxin 13, N-terminal region IMPa_helical PF18642.1 EGC34068.1 - 0.77 10.2 5.1 22 5.5 1.0 3.2 2 2 0 2 2 2 0 Immunomodulating metalloprotease helical domain MRF_C1 PF13887.6 EGC34068.1 - 0.82 8.9 2.9 11 5.2 0.3 2.7 2 0 0 2 2 2 0 Myelin gene regulatory factor -C-terminal domain 1 DUF4041 PF13250.6 EGC34068.1 - 0.93 9.4 6.1 1.5 8.7 0.1 3.6 4 1 0 4 4 4 0 Domain of unknown function (DUF4041) Mannitol_dh PF01232.23 EGC34068.1 - 4.1 7.5 12.9 0.099 12.8 2.8 2.6 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain Pox_A_type_inc PF04508.12 EGC34068.1 - 7.8 6.5 10.1 4.8 7.2 0.4 4.5 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Leg1 PF05612.12 EGC34069.1 - 0.041 13.0 0.1 0.083 12.0 0.1 1.5 1 0 0 1 1 1 0 Leg1 PARP PF00644.20 EGC34070.1 - 7.9e-18 64.7 0.7 1.1e-13 51.2 0.0 2.8 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Actin PF00022.19 EGC34073.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin Nckap1 PF09735.9 EGC34074.1 - 0 1273.3 17.6 0 1273.1 17.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein G-patch PF01585.23 EGC34075.1 - 1.3e-11 44.2 1.5 2.3e-11 43.4 1.5 1.4 1 0 0 1 1 1 1 G-patch domain zf-DBF PF07535.12 EGC34075.1 - 0.00091 19.3 0.6 0.0018 18.3 0.6 1.5 1 0 0 1 1 1 1 DBF zinc finger G-patch_2 PF12656.7 EGC34075.1 - 0.0032 17.5 0.3 0.0032 17.5 0.3 2.2 2 0 0 2 2 2 1 G-patch domain ketoacyl-synt PF00109.26 EGC34076.1 - 1.4e-64 218.1 0.0 2.2e-64 217.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34076.1 - 8.9e-45 153.6 0.0 1.8e-44 152.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34076.1 - 3.1e-31 107.8 0.0 5.8e-31 106.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34076.1 - 3.5e-27 95.5 0.2 1.5e-24 86.9 0.0 2.9 3 0 0 3 3 3 1 KR domain NAD_binding_4 PF07993.12 EGC34076.1 - 5e-26 91.4 0.0 9.5e-26 90.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KAsynt_C_assoc PF16197.5 EGC34076.1 - 9.1e-18 64.8 0.0 2.5e-17 63.3 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC34076.1 - 6.2e-13 48.6 0.0 9.5e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC34076.1 - 6.5e-11 43.4 0.0 2.2e-10 41.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGC34076.1 - 8.4e-08 32.9 0.5 4.7e-07 30.5 0.0 2.7 3 0 0 3 3 1 1 Methyltransferase domain ADH_N PF08240.12 EGC34076.1 - 1.7e-05 24.6 0.0 4.5e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC34076.1 - 4.1e-05 23.5 0.0 9.6e-05 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EGC34076.1 - 4.5e-05 23.0 0.1 0.0037 16.8 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGC34076.1 - 0.0022 18.3 0.0 0.0053 17.1 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF5383 PF17355.2 EGC34076.1 - 0.0094 16.3 0.1 0.031 14.7 0.1 1.9 1 0 0 1 1 1 1 Family of unknown function (DUF5383) Thiolase_N PF00108.23 EGC34076.1 - 0.13 11.5 0.1 0.25 10.7 0.1 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain 2OG-FeII_Oxy_3 PF13640.6 EGC34077.1 - 2.2e-08 34.9 0.0 7.2e-08 33.2 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.13 EGC34077.1 - 0.007 15.5 0.0 0.15 11.1 0.0 2.1 2 0 0 2 2 2 1 Poxvirus C4/C10 protein TPR_8 PF13181.6 EGC34077.1 - 0.031 14.5 0.1 0.083 13.1 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1768 PF08719.11 EGC34078.1 - 1.2e-34 119.9 0.0 1.4e-34 119.7 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.20 EGC34079.1 - 8.4e-16 58.1 5.5 5.9e-14 52.1 0.5 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain adh_short PF00106.25 EGC34079.1 - 2.4e-10 40.2 0.1 3.4e-10 39.7 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC34079.1 - 1.7e-08 34.3 0.0 2.2e-08 33.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase FAM110_N PF14161.6 EGC34080.1 - 0.073 13.3 0.0 0.11 12.8 0.0 1.2 1 0 0 1 1 1 0 Centrosome-associated N terminus FNIP PF05725.12 EGC34081.1 - 3.9e-89 292.6 136.2 5.3e-14 52.1 1.4 11.8 4 1 12 16 16 16 16 FNIP Repeat Dyp_perox PF04261.12 EGC34082.1 - 2.6e-73 246.9 0.0 3.1e-73 246.6 0.0 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family Coagulase PF08764.10 EGC34082.1 - 0.046 13.9 0.1 0.082 13.1 0.1 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Spatacsin_C PF14649.6 EGC34083.1 - 6.9e-104 347.2 6.1 1.8e-103 345.9 6.1 1.8 1 0 0 1 1 1 1 Spatacsin C-terminus TIR_3 PF18567.1 EGC34083.1 - 0.028 14.4 0.2 4.3 7.4 0.1 3.0 2 0 0 2 2 2 0 Toll/interleukin-1 receptor domain FNIP PF05725.12 EGC34085.1 - 1.8e-34 117.7 60.9 2.3e-08 34.0 0.7 11.7 7 4 4 11 11 11 10 FNIP Repeat RNase_T PF00929.24 EGC34087.1 - 6.8e-36 124.3 0.1 7.7e-36 124.1 0.1 1.0 1 0 0 1 1 1 1 Exonuclease DUF5051 PF16473.5 EGC34087.1 - 0.0046 17.0 0.0 0.0052 16.8 0.0 1.2 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like DUF2605 PF10792.9 EGC34087.1 - 0.018 14.9 0.0 0.034 14.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2605) AAA_12 PF13087.6 EGC34088.1 - 9.4e-15 54.8 0.0 9.4e-15 54.8 0.0 3.6 1 1 2 3 3 3 1 AAA domain R3H PF01424.22 EGC34088.1 - 1.2e-13 50.8 0.0 3.7e-13 49.3 0.0 1.9 1 0 0 1 1 1 1 R3H domain AAA_11 PF13086.6 EGC34088.1 - 1.6e-08 34.7 0.9 1.6e-08 34.7 0.9 3.9 3 2 0 4 4 4 1 AAA domain zf-AN1 PF01428.16 EGC34088.1 - 2.5e-07 30.7 8.6 4.3e-07 30.0 8.6 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger Endonuc_BglI PF14562.6 EGC34088.1 - 0.022 13.8 0.0 0.089 11.9 0.0 1.9 2 0 0 2 2 2 0 Restriction endonuclease BglI DUF2052 PF09747.9 EGC34088.1 - 0.98 9.5 30.3 4.1 7.5 16.4 2.8 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) LRR_6 PF13516.6 EGC34090.1 - 0.0036 17.2 0.2 3.9 7.8 0.0 2.4 2 0 0 2 2 2 2 Leucine Rich repeat LRR_4 PF12799.7 EGC34090.1 - 0.0038 17.6 0.2 0.11 13.0 0.1 2.1 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC34090.1 - 0.019 14.7 0.1 0.054 13.3 0.1 1.7 2 0 0 2 2 2 0 Leucine rich repeat NHL PF01436.21 EGC34091.1 - 0.0026 17.7 4.7 13 6.1 0.1 5.2 6 0 0 6 6 6 2 NHL repeat SBBP PF06739.11 EGC34091.1 - 0.023 14.7 3.4 12 6.0 0.1 3.7 3 0 0 3 3 3 0 Beta-propeller repeat Reg_prop PF07494.11 EGC34091.1 - 0.044 14.0 0.3 0.27 11.6 0.3 2.4 1 0 0 1 1 1 0 Two component regulator propeller DUF4692 PF15763.5 EGC34091.1 - 0.085 13.3 0.5 0.085 13.3 0.5 1.7 2 0 0 2 2 2 0 Regulator of human erythroid cell expansion (RHEX) Dyp_perox PF04261.12 EGC34092.1 - 1.5e-110 369.2 0.0 5.5e-56 189.9 0.0 2.0 1 1 1 2 2 2 2 Dyp-type peroxidase family Dyp_perox PF04261.12 EGC34093.1 - 1.4e-64 218.2 0.1 1.7e-64 217.9 0.1 1.1 1 0 0 1 1 1 1 Dyp-type peroxidase family DUF4885 PF16226.5 EGC34093.1 - 0.031 13.3 0.2 0.042 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4885) zf-C3HC4_3 PF13920.6 EGC34094.1 - 1.2e-09 37.9 7.3 2.2e-09 37.0 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.24 EGC34094.1 - 3.9e-09 36.2 1.5 3.9e-09 36.2 1.5 1.8 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_5 PF14634.6 EGC34094.1 - 4e-07 29.9 11.6 8.5e-07 28.8 11.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf_CCCH_4 PF18345.1 EGC34094.1 - 6.9e-07 29.1 3.3 6.9e-07 29.1 3.3 2.1 2 0 0 2 2 1 1 Zinc finger domain zf-C3HC4_2 PF13923.6 EGC34094.1 - 1.4e-06 28.1 11.8 1.4e-06 28.1 11.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC34094.1 - 3.7e-06 26.9 8.6 1.1e-05 25.3 8.6 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC34094.1 - 3.9e-06 26.6 13.4 1e-05 25.3 13.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH_4 PF18044.1 EGC34094.1 - 4.7e-06 26.3 0.9 4.7e-06 26.3 0.9 2.5 2 0 0 2 2 2 1 CCCH-type zinc finger zf-RING_2 PF13639.6 EGC34094.1 - 4e-05 23.9 8.3 4e-05 23.9 8.3 1.8 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGC34094.1 - 0.00011 22.0 7.6 0.00024 20.9 7.6 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC34094.1 - 0.0038 17.3 8.4 0.0097 16.1 8.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGC34094.1 - 0.012 15.7 5.8 0.012 15.7 5.8 2.1 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EGC34094.1 - 0.15 12.4 6.4 0.58 10.5 6.4 2.0 1 0 0 1 1 1 0 RING-H2 zinc finger domain V_ATPase_I PF01496.19 EGC34094.1 - 4 5.2 8.5 7.1 4.4 8.5 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PrgI PF12666.7 EGC34095.1 - 0.2 12.4 4.8 2.1 9.1 1.9 2.3 2 0 0 2 2 2 0 PrgI family protein Ribosomal_S30 PF04758.14 EGC34096.1 - 1.5e-25 89.1 10.7 1.7e-25 88.9 10.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 HALZ PF02183.18 EGC34098.1 - 0.054 13.7 1.5 0.054 13.7 1.5 3.1 3 0 0 3 3 3 0 Homeobox associated leucine zipper DUF2312 PF10073.9 EGC34098.1 - 0.65 9.7 4.0 1.4 8.6 3.9 1.6 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2312) Pkinase_Tyr PF07714.17 EGC34101.1 - 6e-67 225.7 0.1 3.6e-66 223.1 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC34101.1 - 1.1e-57 195.5 0.0 1.1e-57 195.5 0.0 2.6 2 0 0 2 2 1 1 Protein kinase domain Kelch_5 PF13854.6 EGC34101.1 - 1.1e-25 89.2 3.3 0.00026 20.9 0.3 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC34101.1 - 1.2e-22 79.7 11.6 2.8e-07 30.6 0.0 6.9 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_4 PF13418.6 EGC34101.1 - 3.1e-22 78.3 9.9 6.4e-06 26.1 0.1 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC34101.1 - 2.1e-15 56.0 11.4 4e-05 23.1 0.0 6.5 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EGC34101.1 - 2.2e-15 56.3 11.0 9.4e-05 22.6 0.0 6.3 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGC34101.1 - 3e-12 46.0 17.4 0.00013 21.7 0.0 6.3 7 0 0 7 7 7 4 Kelch motif PX PF00787.24 EGC34101.1 - 6.3e-07 29.4 0.9 2.4e-06 27.5 0.2 2.4 2 0 0 2 2 2 1 PX domain PH PF00169.29 EGC34101.1 - 2.2e-05 24.9 1.2 8.2e-05 23.1 0.1 2.7 2 0 0 2 2 1 1 PH domain Kinase-like PF14531.6 EGC34101.1 - 0.0052 16.1 0.0 0.0052 16.1 0.0 1.8 2 0 0 2 2 1 1 Kinase-like CUE PF02845.16 EGC34101.1 - 0.039 13.7 0.1 0.14 11.9 0.1 1.9 1 0 0 1 1 1 0 CUE domain Na_trans_assoc PF06512.13 EGC34101.1 - 0.49 10.6 0.0 0.49 10.6 0.0 6.0 3 2 3 6 6 5 0 Sodium ion transport-associated DUF3276 PF11680.8 EGC34102.1 - 0.062 13.4 9.2 2.2 8.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) Rap_GAP PF02145.15 EGC34104.1 - 7.6e-50 169.0 0.0 2.7e-49 167.2 0.0 2.0 1 0 0 1 1 1 1 Rap/ran-GAP Terpene_synth_C PF03936.16 EGC34105.1 - 0.00045 19.6 3.1 0.00082 18.8 3.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Glyco_transf_22 PF03901.17 EGC34106.1 - 2.3e-45 155.6 31.9 2.9e-45 155.2 31.9 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dicty_CTDC PF00526.18 EGC34107.1 - 2.7e-08 33.6 27.8 4.8e-06 26.4 13.8 5.8 7 0 0 7 7 7 4 Dictyostelium (slime mold) repeat GpcrRhopsn4 PF10192.9 EGC34108.1 - 1.6e-40 139.2 34.0 2.2e-40 138.7 34.0 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain Claudin_2 PF13903.6 EGC34108.1 - 0.0076 16.0 0.1 0.0076 16.0 0.1 2.6 2 1 0 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction GpcrRhopsn4 PF10192.9 EGC34109.1 - 9.7e-42 143.1 27.6 1.2e-41 142.8 27.6 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain GpcrRhopsn4 PF10192.9 EGC34110.1 - 1.7e-58 198.0 38.3 1.7e-58 198.0 38.3 2.0 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EGC34110.1 - 8.4e-06 25.2 28.3 8.4e-06 25.2 28.3 1.5 2 0 0 2 2 2 1 Lung seven transmembrane receptor Acyl_transf_3 PF01757.22 EGC34110.1 - 0.00024 20.3 27.8 0.36 9.9 27.8 2.3 1 1 0 1 1 1 1 Acyltransferase family DUF4231 PF14015.6 EGC34110.1 - 9 6.8 6.7 11 6.6 0.3 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) FNIP PF05725.12 EGC34111.1 - 3e-59 196.9 95.8 5.8e-09 36.0 0.5 14.4 8 3 8 16 16 16 15 FNIP Repeat Mucin PF01456.17 EGC34113.1 - 0.00014 21.9 1.5 0.00018 21.5 1.5 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.11 EGC34113.1 - 0.2 9.8 6.4 0.29 9.3 6.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 p450 PF00067.22 EGC34114.1 - 1.2e-18 67.1 0.0 1.3e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECH_1 PF00378.20 EGC34115.1 - 3.4e-42 144.5 0.0 4.3e-42 144.2 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC34115.1 - 2.3e-18 66.8 0.0 3.1e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGC34115.1 - 0.051 13.5 0.0 12 5.8 0.0 2.5 3 0 0 3 3 3 0 Peptidase family S49 Patatin PF01734.22 EGC34116.1 - 0.0076 16.4 0.0 0.03 14.5 0.0 2.0 1 1 0 1 1 1 1 Patatin-like phospholipase SYF2 PF08231.12 EGC34116.1 - 1.3 9.4 11.9 1.2 9.5 5.5 2.5 2 1 0 2 2 2 0 SYF2 splicing factor Patatin PF01734.22 EGC34117.1 - 2.1e-21 77.0 0.0 3.5e-21 76.3 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase SYF2 PF08231.12 EGC34117.1 - 0.022 15.1 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 SYF2 splicing factor MA3 PF02847.17 EGC34118.1 - 8.2e-25 87.0 1.0 2.1e-24 85.7 1.0 1.8 1 0 0 1 1 1 1 MA3 domain CCDC106 PF15794.5 EGC34118.1 - 3.6 7.3 16.2 0.2 11.4 7.7 2.3 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 106 Ammonium_transp PF00909.21 EGC34119.1 - 3.5e-100 335.5 28.5 3.9e-100 335.3 28.5 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DLH PF01738.18 EGC34120.1 - 1.1e-34 119.9 0.0 1.3e-34 119.7 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGC34120.1 - 0.00091 19.1 0.0 0.0012 18.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase BAAT_C PF08840.11 EGC34120.1 - 0.0012 18.8 0.1 0.0034 17.3 0.0 1.6 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EGC34120.1 - 0.0054 16.0 0.1 0.53 9.5 0.0 2.0 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGC34120.1 - 0.01 14.8 0.0 0.13 11.2 0.0 2.4 1 1 2 3 3 3 0 Chlorophyllase enzyme Chlorophyllase PF07224.11 EGC34120.1 - 0.021 13.9 0.0 0.14 11.2 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase Peptidase_S9 PF00326.21 EGC34120.1 - 0.041 13.4 0.8 1.5 8.3 0.1 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Esterase PF00756.20 EGC34120.1 - 0.064 12.9 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase Glycos_transf_2 PF00535.26 EGC34120.1 - 0.14 12.0 0.0 2.2 8.0 0.0 2.1 2 0 0 2 2 2 0 Glycosyl transferase family 2 Abhydrolase_6 PF12697.7 EGC34120.1 - 0.19 12.3 0.0 0.25 11.9 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGC34120.1 - 0.2 11.3 0.2 0.77 9.4 0.1 1.8 1 1 1 2 2 2 0 alpha/beta hydrolase fold DUF2670 PF10875.8 EGC34122.1 - 0.051 13.7 0.2 0.071 13.2 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) F-box-like PF12937.7 EGC34123.1 - 0.0015 18.4 0.3 0.005 16.7 0.0 1.9 2 0 0 2 2 2 1 F-box-like COesterase PF00135.28 EGC34124.1 - 2.2e-99 333.7 0.0 6.8e-67 226.5 0.0 2.3 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC34124.1 - 0.0028 17.5 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC34124.1 - 0.019 14.4 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC34124.1 - 0.023 13.9 0.0 0.046 13.0 0.0 1.4 1 0 0 1 1 1 0 Serine aminopeptidase, S33 COesterase PF00135.28 EGC34125.1 - 4.3e-120 402.0 0.0 2.1e-119 399.7 0.0 1.8 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC34125.1 - 0.0029 17.5 0.2 0.015 15.2 0.2 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34125.1 - 0.028 13.7 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC34125.1 - 0.1 12.1 0.0 0.17 11.3 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family MutS_IV PF05190.18 EGC34126.1 - 3.6 8.0 10.9 0.7 10.3 3.3 3.5 4 0 0 4 4 4 0 MutS family domain IV FSH1 PF03959.13 EGC34127.1 - 1.1e-50 172.2 0.7 5.4e-37 127.5 0.1 2.6 2 1 0 2 2 2 2 Serine hydrolase (FSH1) BAAT_C PF08840.11 EGC34127.1 - 0.028 14.4 0.0 0.48 10.3 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.20 EGC34127.1 - 0.033 13.8 2.1 0.22 11.1 2.1 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGC34127.1 - 0.12 12.1 0.4 17 5.1 0.1 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Complex1_LYR PF05347.15 EGC34128.1 - 1.2e-12 47.6 0.4 1.5e-12 47.3 0.4 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC34128.1 - 0.00031 21.4 0.6 0.00033 21.3 0.6 1.1 1 0 0 1 1 1 1 Complex1_LYR-like C2 PF00168.30 EGC34129.1 - 5.2e-25 87.7 0.0 9.6e-25 86.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain MCM_bind PF09739.9 EGC34130.1 - 2.6e-148 495.1 21.4 1.1e-118 397.3 12.3 2.0 1 1 1 2 2 2 2 Mini-chromosome maintenance replisome factor MCM_lid PF17855.1 EGC34130.1 - 0.18 12.3 0.0 0.37 11.2 0.0 1.5 1 0 0 1 1 1 0 MCM AAA-lid domain CRAL_TRIO PF00650.20 EGC34131.1 - 3e-32 111.5 0.2 4.2e-32 111.1 0.2 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGC34131.1 - 2.4e-07 30.8 1.2 2.4e-07 30.8 1.2 1.9 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.6 EGC34131.1 - 0.00011 22.4 0.2 0.00016 21.8 0.2 1.3 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF1279 PF06916.13 EGC34132.1 - 0.023 15.2 0.7 0.1 13.1 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) PNTB PF02233.16 EGC34132.1 - 2.2 7.1 4.5 2 7.2 3.5 1.3 1 1 0 1 1 1 0 NAD(P) transhydrogenase beta subunit NAGLU_N PF12971.7 EGC34133.1 - 2.1 8.2 8.2 1.4 8.8 0.1 2.8 3 0 0 3 3 3 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain DsbB PF02600.16 EGC34133.1 - 4.4 7.7 14.2 47 4.4 0.3 3.7 1 1 1 2 2 2 0 Disulfide bond formation protein DsbB Clat_adaptor_s PF01217.20 EGC34134.1 - 2.2e-14 53.6 2.3 2.8e-14 53.3 2.3 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ribosomal_S5 PF00333.20 EGC34135.1 - 5.3e-11 42.3 0.6 5.3e-11 42.3 0.6 2.0 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGC34135.1 - 0.012 15.1 0.0 0.047 13.2 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain DUF1759 PF03564.15 EGC34135.1 - 8.9 6.2 12.1 1.3 9.0 0.1 4.2 4 1 1 5 5 5 0 Protein of unknown function (DUF1759) Xpo1 PF08389.12 EGC34136.1 - 1.2e-16 61.1 21.2 3.6e-16 59.6 0.3 6.2 5 2 2 7 7 7 3 Exportin 1-like protein TFCD_C PF12612.8 EGC34136.1 - 0.0017 18.2 0.2 0.014 15.2 0.1 2.7 1 1 1 2 2 2 1 Tubulin folding cofactor D C terminal DUF4042 PF13251.6 EGC34136.1 - 0.0023 17.7 0.4 0.14 11.9 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) DUF1722 PF08349.11 EGC34136.1 - 0.061 13.6 0.1 0.061 13.6 0.1 4.3 5 0 0 5 5 5 0 Protein of unknown function (DUF1722) IBN_N PF03810.19 EGC34136.1 - 1.2 9.1 8.3 0.45 10.5 0.7 3.8 3 0 0 3 3 3 0 Importin-beta N-terminal domain C2 PF00168.30 EGC34138.1 - 2.1e-18 66.5 0.0 4.1e-18 65.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain VASt PF16016.5 EGC34139.1 - 2.6e-16 60.4 0.1 2.6e-16 60.4 0.1 2.4 2 0 0 2 2 2 1 VAD1 Analog of StAR-related lipid transfer domain ThrE PF06738.12 EGC34139.1 - 0.23 10.8 0.4 0.66 9.3 0.4 1.7 1 1 0 1 1 1 0 Putative threonine/serine exporter DUF2367 PF10164.9 EGC34139.1 - 1.1 9.8 3.8 11 6.5 4.4 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2367) eIF-3_zeta PF05091.12 EGC34140.1 - 6.6 5.6 27.8 0.35 9.8 21.7 1.7 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FOXP-CC PF16159.5 EGC34141.1 - 2.6e-10 40.8 16.0 0.011 16.3 0.1 5.6 2 2 3 5 5 5 4 FOXP coiled-coil domain zf-H2C2_2 PF13465.6 EGC34141.1 - 8.3e-05 22.8 1.9 8.3e-05 22.8 1.9 4.5 5 0 0 5 5 5 1 Zinc-finger double domain zf-C2H2 PF00096.26 EGC34141.1 - 0.0013 19.1 23.0 0.35 11.4 1.0 5.5 6 0 0 6 6 6 4 Zinc finger, C2H2 type Glyco_hydro_25 PF01183.20 EGC34142.1 - 4e-15 56.4 0.0 4.6e-15 56.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Pox_E10 PF04805.12 EGC34142.1 - 0.18 11.7 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 E10-like protein conserved region WD40 PF00400.32 EGC34143.1 - 2.1e-13 50.5 7.9 1.6e-05 25.5 0.3 6.5 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34143.1 - 3.1e-05 24.2 1.3 1 9.7 0.0 4.0 3 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain DHR-2 PF06920.13 EGC34144.1 - 7.1e-174 579.3 20.8 1.2e-173 578.6 20.8 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EGC34144.1 - 1.6e-46 158.6 1.4 6.1e-46 156.7 1.4 2.1 1 0 0 1 1 1 1 C2 domain in Dock180 and Zizimin proteins Ipi1_N PF12333.8 EGC34144.1 - 0.0017 18.9 0.8 0.024 15.2 0.0 3.3 3 0 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation RasGAP_C PF03836.15 EGC34144.1 - 0.26 11.5 3.8 1.4 9.1 3.4 2.6 1 1 0 1 1 1 0 RasGAP C-terminus Reticulon PF02453.17 EGC34145.1 - 1.2e-23 83.8 9.4 2.8e-23 82.6 9.4 1.6 1 0 0 1 1 1 1 Reticulon Apolipoprotein PF01442.18 EGC34145.1 - 1.5e-05 25.0 4.8 2.4e-05 24.3 4.8 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Gp-FAR-1 PF05823.12 EGC34145.1 - 0.0012 19.2 1.2 0.0025 18.2 1.2 1.6 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) Baculo_PEP_C PF04513.12 EGC34145.1 - 0.0018 18.3 5.8 0.0045 17.0 3.0 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.7 EGC34145.1 - 0.003 18.1 14.8 0.5 10.9 14.8 2.4 1 1 0 1 1 1 1 YtxH-like protein Phage_Mu_Gam PF07352.12 EGC34145.1 - 0.0079 16.1 3.7 0.0079 16.1 3.7 2.7 2 1 1 3 3 3 1 Bacteriophage Mu Gam like protein PIN_8 PF18476.1 EGC34145.1 - 0.013 15.3 2.3 0.022 14.6 2.3 1.4 1 0 0 1 1 1 0 PIN like domain ApoLp-III PF07464.11 EGC34145.1 - 0.016 15.3 13.8 0.016 15.3 13.8 1.8 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) ApoO PF09769.9 EGC34145.1 - 0.018 15.0 2.5 0.051 13.5 1.0 2.2 1 1 1 2 2 2 0 Apolipoprotein O DUF883 PF05957.13 EGC34145.1 - 0.018 15.6 3.5 0.11 13.1 3.5 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.8 EGC34145.1 - 0.029 13.6 5.7 0.043 13.0 5.7 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein HBM PF16591.5 EGC34145.1 - 0.03 13.8 0.5 0.043 13.2 0.5 1.3 1 0 0 1 1 1 0 Helical bimodular sensor domain DUF4795 PF16043.5 EGC34145.1 - 0.032 13.9 2.3 0.061 12.9 2.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) CdvA PF18822.1 EGC34145.1 - 0.035 13.9 9.7 0.15 11.9 5.7 2.9 2 1 1 3 3 3 0 CdvA-like coiled-coil domain HIP1_clath_bdg PF16515.5 EGC34145.1 - 0.04 14.5 7.4 0.07 13.7 7.4 1.5 1 0 0 1 1 1 0 Clathrin-binding domain of Huntingtin-interacting protein 1 DUF1451 PF07295.11 EGC34145.1 - 0.046 13.8 3.9 0.53 10.3 4.5 2.1 2 0 0 2 2 2 0 Zinc-ribbon containing domain Syntaxin PF00804.25 EGC34145.1 - 0.059 13.0 6.9 0.26 11.0 6.9 1.9 1 1 0 1 1 1 0 Syntaxin DUF1043 PF06295.12 EGC34145.1 - 0.061 13.3 2.4 0.43 10.6 2.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1043) Baculo_p24 PF05073.12 EGC34145.1 - 0.073 12.8 5.3 0.21 11.3 5.3 1.7 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Fzo_mitofusin PF04799.13 EGC34145.1 - 0.08 12.5 6.6 0.12 11.9 4.6 2.2 1 1 1 2 2 2 0 fzo-like conserved region ORMDL PF04061.14 EGC34145.1 - 0.096 12.5 3.9 0.19 11.5 3.9 1.4 1 1 0 1 1 1 0 ORMDL family DUF1664 PF07889.12 EGC34145.1 - 0.1 12.7 13.7 0.031 14.3 7.7 3.0 3 1 1 4 4 3 0 Protein of unknown function (DUF1664) dCache_2 PF08269.11 EGC34145.1 - 0.12 11.5 7.6 0.2 10.8 7.6 1.3 1 0 0 1 1 1 0 Cache domain DUF4407 PF14362.6 EGC34145.1 - 0.12 11.7 1.3 0.24 10.7 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) WXG100 PF06013.12 EGC34145.1 - 0.17 12.2 0.5 0.35 11.1 0.5 1.5 1 0 0 1 1 1 0 Proteins of 100 residues with WXG MIS13 PF08202.11 EGC34145.1 - 0.18 11.0 3.6 0.34 10.2 3.6 1.5 1 0 0 1 1 1 0 Mis12-Mtw1 protein family HisKA_3 PF07730.13 EGC34145.1 - 0.19 12.3 0.2 5.3 7.6 0.1 3.0 3 1 1 4 4 3 0 Histidine kinase LCD1 PF09798.9 EGC34145.1 - 0.26 9.8 9.4 0.44 9.0 9.4 1.5 1 1 0 1 1 1 0 DNA damage checkpoint protein BshC PF10079.9 EGC34145.1 - 0.27 9.9 5.7 0.38 9.5 5.7 1.2 1 0 0 1 1 1 0 Bacillithiol biosynthesis BshC RmuC PF02646.16 EGC34145.1 - 0.27 10.3 5.1 0.54 9.3 5.1 1.5 1 0 0 1 1 1 0 RmuC family DUF2203 PF09969.9 EGC34145.1 - 0.31 11.8 1.7 0.82 10.4 1.7 1.7 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF2746 PF10874.8 EGC34145.1 - 0.36 11.3 5.6 9.3 6.7 0.2 3.1 2 2 1 3 3 2 0 Protein of unknown function (DUF2746) AAA_32 PF13654.6 EGC34145.1 - 0.4 9.4 4.6 0.57 8.9 4.6 1.2 1 0 0 1 1 1 0 AAA domain DUF4533 PF15047.6 EGC34145.1 - 0.48 9.9 6.2 0.39 10.2 4.1 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF4533) LPP PF04728.13 EGC34145.1 - 0.5 10.8 10.1 1.6 9.1 4.1 3.2 1 1 1 2 2 2 0 Lipoprotein leucine-zipper DUF1640 PF07798.11 EGC34145.1 - 0.5 10.4 6.1 0.99 9.4 6.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1640) Z1 PF10593.9 EGC34145.1 - 0.51 9.8 3.4 1.3 8.4 2.0 2.0 2 1 0 2 2 2 0 Z1 domain Syntaxin-6_N PF09177.11 EGC34145.1 - 0.55 10.8 9.2 1.1 9.8 8.2 2.0 2 0 0 2 2 1 0 Syntaxin 6, N-terminal DUF5082 PF16888.5 EGC34145.1 - 0.59 10.4 7.0 0.37 11.1 3.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF5082) EspB PF05802.11 EGC34145.1 - 0.6 10.1 6.9 2.5 8.0 6.7 2.1 2 1 0 2 2 2 0 Enterobacterial EspB protein LXG PF04740.12 EGC34145.1 - 0.63 9.7 9.2 12 5.5 0.8 2.7 2 1 0 2 2 1 0 LXG domain of WXG superfamily V-SNARE PF05008.15 EGC34145.1 - 0.65 10.4 7.2 1.7 9.1 1.7 2.8 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Type2_restr_D3 PF16902.5 EGC34145.1 - 0.66 9.9 2.4 0.76 9.7 0.9 2.0 2 0 0 2 2 1 0 Type-2 restriction enzyme D3 domain YkyA PF10368.9 EGC34145.1 - 0.78 9.4 10.5 1.5 8.5 10.5 1.5 1 0 0 1 1 1 0 Putative cell-wall binding lipoprotein APG17 PF04108.12 EGC34145.1 - 0.81 8.7 5.1 1.3 8.1 5.1 1.3 1 0 0 1 1 1 0 Autophagy protein Apg17 Spc7 PF08317.11 EGC34145.1 - 0.82 8.5 8.8 1.2 7.9 8.8 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF2205 PF10224.9 EGC34145.1 - 0.83 9.7 7.0 1.6 8.8 5.8 2.2 1 1 0 1 1 1 0 Short coiled-coil protein FlaC_arch PF05377.11 EGC34145.1 - 0.88 10.0 21.0 0.75 10.2 1.6 4.0 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) MCPsignal PF00015.21 EGC34145.1 - 0.98 9.2 16.9 1.5 8.6 11.6 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Golgin_A5 PF09787.9 EGC34145.1 - 1 8.7 6.6 1.5 8.2 6.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Spectrin PF00435.21 EGC34145.1 - 1.1 9.8 4.8 2.6 8.6 4.8 1.7 1 0 0 1 1 1 0 Spectrin repeat DUF3584 PF12128.8 EGC34145.1 - 1.2 6.5 6.7 1.7 6.1 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Laminin_II PF06009.12 EGC34145.1 - 1.4 9.0 13.1 1.8 8.5 10.4 2.4 2 1 0 2 2 2 0 Laminin Domain II DUF948 PF06103.11 EGC34145.1 - 1.4 9.2 13.5 1.9 8.8 8.1 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) NPV_P10 PF05531.12 EGC34145.1 - 1.5 9.3 14.0 19 5.8 10.1 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein TPR_MLP1_2 PF07926.12 EGC34145.1 - 2.1 8.4 9.6 8.2 6.5 9.6 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Snapin_Pallidin PF14712.6 EGC34145.1 - 2.2 8.8 5.6 1.4 9.4 2.8 2.2 2 1 0 2 2 1 0 Snapin/Pallidin COG2 PF06148.11 EGC34145.1 - 2.4 8.3 11.5 4.5 7.4 4.9 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Lipoprotein_2 PF00921.17 EGC34145.1 - 2.5 7.6 17.0 0.33 10.5 12.6 1.7 2 0 0 2 2 2 0 Borrelia lipoprotein DUF1542 PF07564.11 EGC34145.1 - 2.7 8.2 18.1 0.42 10.7 4.9 2.8 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1542) PRD PF00874.20 EGC34145.1 - 3.3 8.1 7.0 1.4 9.2 0.1 3.2 3 1 0 3 3 2 0 PRD domain Bacillus_HBL PF05791.11 EGC34145.1 - 3.5 7.4 9.4 2.2 8.1 6.6 2.0 2 0 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) XhlA PF10779.9 EGC34145.1 - 4 7.7 11.9 0.84 9.9 5.9 2.8 2 1 1 3 3 3 0 Haemolysin XhlA HSCB_C PF07743.13 EGC34145.1 - 4.1 8.0 10.1 14 6.3 6.6 2.7 2 1 1 3 3 2 0 HSCB C-terminal oligomerisation domain IFT57 PF10498.9 EGC34145.1 - 5 6.0 10.0 8.5 5.2 10.0 1.3 1 0 0 1 1 1 0 Intra-flagellar transport protein 57 Fib_alpha PF08702.10 EGC34145.1 - 5.1 7.3 9.9 0.88 9.7 5.0 2.3 3 1 0 3 3 1 0 Fibrinogen alpha/beta chain family Phasin PF05597.11 EGC34145.1 - 5.3 7.0 12.1 8.1 6.5 5.6 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF148 PF02520.17 EGC34145.1 - 6.3 7.0 10.4 19 5.4 10.4 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF148 DUF4854 PF16146.5 EGC34145.1 - 6.9 7.1 8.7 1.9e+02 2.4 8.7 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4854) Seryl_tRNA_N PF02403.22 EGC34145.1 - 7 6.9 12.9 29 4.9 12.9 2.1 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain ORF6C PF10552.9 EGC34145.1 - 8.5 6.5 9.8 3 8.0 3.0 2.7 1 1 1 2 2 2 0 ORF6C domain AAA_13 PF13166.6 EGC34145.1 - 8.8 4.8 11.8 11 4.5 10.7 1.6 2 0 0 2 2 2 0 AAA domain HlyIII PF03006.20 EGC34146.1 - 7.7e-48 163.1 21.1 9.9e-48 162.8 21.1 1.1 1 0 0 1 1 1 1 Haemolysin-III related BROMI PF14961.6 EGC34146.1 - 0.057 10.8 0.9 0.084 10.3 0.9 1.1 1 0 0 1 1 1 0 Broad-minded protein Aa_trans PF01490.18 EGC34147.1 - 3.2e-56 190.8 31.8 4e-56 190.5 31.8 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein DUF92 PF01940.16 EGC34147.1 - 0.29 10.5 4.7 0.2 11.1 1.4 2.3 2 0 0 2 2 2 0 Integral membrane protein DUF92 SPC12 PF06645.13 EGC34147.1 - 0.31 11.1 0.2 0.31 11.1 0.2 3.9 5 1 1 6 6 6 0 Microsomal signal peptidase 12 kDa subunit (SPC12) RseC_MucC PF04246.12 EGC34147.1 - 8.3 6.4 10.1 8.1 6.4 0.3 3.3 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC PIP5K PF01504.18 EGC34148.1 - 9.9e-28 97.1 9.0 2.6e-21 76.1 4.7 2.2 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Med3 PF11593.8 EGC34148.1 - 0.56 9.3 11.2 1.3 8.1 2.1 2.1 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Mucin PF01456.17 EGC34149.1 - 0.0069 16.4 7.0 0.012 15.6 7.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein 7TM_GPCR_Srd PF10317.9 EGC34149.1 - 0.33 10.1 8.6 0.24 10.6 7.0 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF3439 PF11921.8 EGC34149.1 - 0.62 10.0 7.0 1.9 8.4 7.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2615 PF11027.8 EGC34149.1 - 7 6.8 13.8 2.7 8.2 5.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF2615) CHASE PF03924.13 EGC34150.1 - 2.5e-31 109.1 0.0 4.5e-31 108.3 0.0 1.5 1 0 0 1 1 1 1 CHASE domain HATPase_c PF02518.26 EGC34150.1 - 4e-30 104.6 0.2 9.4e-30 103.4 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC34150.1 - 4.3e-22 78.4 0.1 2.4e-21 76.0 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGC34150.1 - 3.9e-20 71.6 0.1 9.2e-20 70.5 0.1 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.12 EGC34150.1 - 2.3e-07 31.0 0.0 6.7e-07 29.5 0.0 1.7 1 0 0 1 1 1 1 PAS fold TIG PF01833.24 EGC34151.1 - 6.5e-05 22.9 11.3 0.018 15.1 0.5 4.0 3 0 0 3 3 3 2 IPT/TIG domain EGF_2 PF07974.13 EGC34151.1 - 0.88 10.0 4.6 2.7 8.5 4.6 1.8 1 0 0 1 1 1 0 EGF-like domain DUF2428 PF10350.9 EGC34153.1 - 9.7e-82 274.3 0.2 3.4e-81 272.5 0.2 2.0 1 0 0 1 1 1 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.22 EGC34153.1 - 0.00018 21.4 0.2 1.7 9.1 0.0 4.7 4 0 0 4 4 4 1 HEAT repeat Kelch_6 PF13964.6 EGC34154.1 - 2.3e-10 40.4 4.6 4.1e-05 23.7 0.1 4.5 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 EGC34154.1 - 1.8e-07 31.1 3.0 0.021 14.8 0.0 4.1 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-C3HC4_2 PF13923.6 EGC34154.1 - 4.3e-07 29.7 10.9 4.3e-07 29.7 10.9 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC34154.1 - 8.1e-07 28.8 10.9 8.1e-07 28.8 10.9 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.25 EGC34154.1 - 1e-06 28.2 7.4 0.016 14.8 0.2 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.15 EGC34154.1 - 1.7e-05 24.6 1.4 0.68 10.0 0.0 4.4 4 0 0 4 4 4 1 Kelch motif zf-B_box PF00643.24 EGC34154.1 - 2.8e-05 24.2 7.2 2.8e-05 24.2 7.2 3.0 2 1 0 2 2 2 1 B-box zinc finger Kelch_5 PF13854.6 EGC34154.1 - 5.7e-05 23.0 9.1 0.11 12.5 0.0 4.2 5 0 0 5 5 4 2 Kelch motif zf-C3HC4_4 PF15227.6 EGC34154.1 - 0.00039 20.5 9.6 0.00039 20.5 9.6 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGC34154.1 - 0.00073 19.8 9.6 0.00073 19.8 9.6 3.1 3 0 0 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC34154.1 - 0.0036 17.3 12.7 0.012 15.6 10.5 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-MIZ PF02891.20 EGC34154.1 - 0.013 15.3 9.1 0.036 13.8 9.1 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.6 EGC34154.1 - 0.014 15.3 4.2 0.052 13.4 4.2 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGC34154.1 - 0.017 14.9 12.1 0.017 14.9 12.1 2.9 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 DUF5074 PF16819.5 EGC34154.1 - 0.02 14.9 0.7 0.069 13.2 0.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF5074) Kelch_3 PF13415.6 EGC34154.1 - 0.023 15.0 0.4 1.4 9.3 0.2 2.9 2 0 0 2 2 2 0 Galactose oxidase, central domain zf-RING_5 PF14634.6 EGC34154.1 - 3.8 7.6 18.4 0.035 14.1 8.5 2.6 2 0 0 2 2 2 0 zinc-RING finger domain zf-Nse PF11789.8 EGC34154.1 - 8 6.4 10.8 11 6.0 9.4 1.9 2 0 0 2 2 1 0 Zinc-finger of the MIZ type in Nse subunit OrfB_Zn_ribbon PF07282.11 EGC34155.1 - 3.9e-05 23.5 0.2 0.047 13.6 0.0 2.3 2 0 0 2 2 2 2 Putative transposase DNA-binding domain RNA_pol_Rpb1_1 PF04997.12 EGC34156.1 - 7.2e-21 74.8 0.0 9.4e-21 74.4 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 Cofilin_ADF PF00241.20 EGC34157.1 - 9.2e-06 25.5 0.0 1.1e-05 25.2 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein WD40 PF00400.32 EGC34158.1 - 2.6e-21 75.5 24.9 0.0013 19.5 0.3 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.7 EGC34158.1 - 6.1e-09 35.6 0.6 1.4e-08 34.5 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGC34158.1 - 1.2e-05 25.1 1.8 1.5e-05 24.7 0.4 2.1 2 0 0 2 2 2 1 F-box domain DNA_repr_REX1B PF14966.6 EGC34161.1 - 0.22 12.2 3.3 0.17 12.6 0.4 2.3 2 0 0 2 2 2 0 DNA repair REX1-B zf-C2H2 PF00096.26 EGC34162.1 - 6.3e-24 83.0 73.6 0.00024 21.4 5.2 9.4 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGC34162.1 - 3.4e-15 55.4 74.5 0.014 16.2 1.0 9.6 9 0 0 9 9 9 8 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGC34162.1 - 1.1e-08 35.1 67.3 5.9e-07 29.6 0.9 8.9 10 0 0 10 10 10 5 Zinc-finger double domain zf-C2H2_8 PF15909.5 EGC34162.1 - 0.00023 21.4 34.1 0.0084 16.4 7.4 5.3 2 1 3 5 5 5 4 C2H2-type zinc ribbon zf_Hakai PF18408.1 EGC34162.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 6.2 7 0 0 7 7 7 2 C2H2 Hakai zinc finger domain FOXP-CC PF16159.5 EGC34162.1 - 0.14 12.8 0.2 0.14 12.8 0.2 7.5 3 2 5 8 8 8 0 FOXP coiled-coil domain C2 PF00168.30 EGC34163.1 - 1e-05 25.8 0.0 5.9e-05 23.3 0.0 2.4 1 0 0 1 1 1 1 C2 domain TMF_TATA_bd PF12325.8 EGC34163.1 - 0.0076 16.5 10.8 0.0076 16.5 10.8 9.1 5 2 3 9 9 9 2 TATA element modulatory factor 1 TATA binding RCC1 PF00415.18 EGC34164.1 - 7.9e-24 84.0 0.4 2.2e-06 28.2 0.0 7.8 8 1 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC34164.1 - 5.3e-22 77.1 15.8 0.0001 22.0 0.1 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Profilin PF00235.19 EGC34164.1 - 0.00041 20.6 0.1 0.001 19.3 0.1 1.6 1 0 0 1 1 1 1 Profilin Kelch_4 PF13418.6 EGC34164.1 - 0.96 9.5 2.7 11 6.2 0.1 3.2 2 1 1 3 3 3 0 Galactose oxidase, central domain CTP_synth_N PF06418.14 EGC34165.1 - 4.6e-126 419.6 0.0 8.8e-126 418.6 0.0 1.5 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.28 EGC34165.1 - 5.3e-57 192.7 0.0 8.4e-57 192.0 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.13 EGC34165.1 - 0.0011 18.8 0.4 0.014 15.1 0.4 2.5 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.23 EGC34165.1 - 0.12 12.5 0.0 0.38 10.8 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAD_binding_2 PF00890.24 EGC34166.1 - 4e-123 411.6 4.5 5.3e-123 411.2 4.5 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.20 EGC34166.1 - 4.9e-43 146.2 1.7 8.1e-43 145.5 1.7 1.4 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.14 EGC34166.1 - 5.6e-05 22.5 0.3 0.00032 20.0 0.0 2.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGC34166.1 - 0.00012 21.3 3.1 0.059 12.4 2.3 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A DAO PF01266.24 EGC34166.1 - 0.00014 21.6 1.1 0.0015 18.2 1.1 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGC34166.1 - 0.00025 20.3 0.1 0.037 13.3 0.0 2.9 3 0 0 3 3 3 1 Thi4 family FAD_binding_3 PF01494.19 EGC34166.1 - 0.0034 16.7 0.2 0.0066 15.7 0.2 1.5 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGC34166.1 - 0.043 12.5 0.0 0.23 10.1 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Dor1 PF04124.12 EGC34166.1 - 0.088 11.5 0.6 0.13 10.9 0.6 1.2 1 0 0 1 1 1 0 Dor1-like family Chromosome_seg PF13889.6 EGC34167.1 - 1e-21 76.8 3.1 2.2e-21 75.7 3.1 1.6 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.6 EGC34167.1 - 9e-13 48.6 0.2 3.5e-12 46.7 0.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4210) LRR_6 PF13516.6 EGC34168.1 - 5.8e-12 44.7 45.9 0.0011 18.9 0.2 10.9 12 0 0 12 12 12 6 Leucine Rich repeat F-box PF00646.33 EGC34168.1 - 0.019 14.8 1.2 5.9 6.9 0.1 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGC34168.1 - 0.049 13.5 0.4 6.2 6.8 0.2 2.7 2 0 0 2 2 2 0 F-box-like Claudin_2 PF13903.6 EGC34168.1 - 0.097 12.4 0.1 0.097 12.4 0.1 2.9 4 0 0 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction PulG PF11773.8 EGC34168.1 - 0.1 12.4 3.8 0.12 12.2 1.1 2.5 2 0 0 2 2 2 0 Type II secretory pathway pseudopilin DUF2570 PF10828.8 EGC34168.1 - 2.3 8.1 11.8 0.27 11.1 3.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) UcrQ PF02939.16 EGC34169.1 - 7.5e-13 48.2 0.5 9e-13 48.0 0.5 1.0 1 0 0 1 1 1 1 UcrQ family Cyt_b-c1_8 PF10890.8 EGC34169.1 - 4.2e-08 33.5 0.2 4.7e-08 33.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b-c1 complex subunit 8 Snf7 PF03357.21 EGC34170.1 - 8.8e-33 113.3 16.6 1.1e-32 113.0 16.6 1.0 1 0 0 1 1 1 1 Snf7 Planc_extracel PF07595.12 EGC34170.1 - 0.075 12.8 1.0 0.17 11.7 1.0 1.6 1 0 0 1 1 1 0 Planctomycete extracellular Uds1 PF15456.6 EGC34170.1 - 2.1 8.5 12.3 0.08 13.1 0.5 2.4 1 1 1 2 2 2 0 Up-regulated During Septation VCBS PF13517.6 EGC34171.1 - 4.3e-08 33.6 2.4 0.22 12.2 0.0 3.8 4 0 0 4 4 4 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.23 EGC34171.1 - 0.0015 18.6 11.5 0.15 12.2 0.2 3.5 3 0 0 3 3 3 3 FG-GAP repeat PA26 PF04636.13 EGC34172.1 - 0.48 9.3 12.1 1.2 8.0 0.3 2.3 2 0 0 2 2 2 0 PA26 p53-induced protein (sestrin) Macoilin PF09726.9 EGC34172.1 - 2.6 6.5 31.7 0.33 9.5 17.4 2.3 2 0 0 2 2 2 0 Macoilin family Kinesin_assoc PF16183.5 EGC34172.1 - 6.4 6.9 16.4 0.075 13.2 4.4 2.7 3 0 0 3 3 3 0 Kinesin-associated eIF-4B PF06273.11 EGC34172.1 - 8 5.4 10.8 0.054 12.5 0.8 2.3 3 0 0 3 3 3 0 Plant specific eukaryotic initiation factor 4B Cyt-b5 PF00173.28 EGC34173.1 - 7.8e-23 80.4 0.1 1.1e-22 80.0 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EF-hand_5 PF13202.6 EGC34173.1 - 0.0079 15.7 0.1 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.6 EGC34173.1 - 0.065 13.2 0.1 0.17 11.9 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain EF-hand_1 PF00036.32 EGC34173.1 - 0.12 11.9 0.1 0.37 10.5 0.1 1.8 1 0 0 1 1 1 0 EF hand Complex1_LYR_2 PF13233.6 EGC34174.1 - 8e-11 42.5 11.2 3.9e-10 40.3 11.2 2.0 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.15 EGC34174.1 - 3.7e-07 30.1 0.3 3.7e-07 30.1 0.3 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) SieB PF14163.6 EGC34174.1 - 0.15 11.6 8.2 0.13 11.7 0.9 2.2 2 0 0 2 2 2 0 Super-infection exclusion protein B APG6_N PF17675.1 EGC34174.1 - 0.76 10.3 13.7 1.1 9.8 13.7 1.3 1 0 0 1 1 1 0 Apg6 coiled-coil region GATA PF00320.27 EGC34178.1 - 0.074 12.7 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 GATA zinc finger Gcd10p PF04189.13 EGC34179.1 - 2.5e-61 207.4 12.8 4.3e-61 206.6 12.0 1.9 1 1 0 1 1 1 1 Gcd10p family PX PF00787.24 EGC34179.1 - 0.079 13.0 0.4 0.23 11.5 0.4 1.8 1 0 0 1 1 1 0 PX domain GEMIN8 PF15348.6 EGC34180.1 - 0.11 12.7 2.7 0.13 12.6 2.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DUF4820 PF16091.5 EGC34180.1 - 3.5 6.9 8.1 5.1 6.4 8.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) Dapper PF15268.6 EGC34180.1 - 6.4 5.5 11.4 7.1 5.4 11.4 1.0 1 0 0 1 1 1 0 Dapper Presenilin PF01080.17 EGC34180.1 - 8.6 5.0 12.7 11 4.6 12.7 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.9 EGC34180.1 - 9.2 4.7 22.3 9.6 4.6 22.3 1.0 1 0 0 1 1 1 0 Macoilin family PHB_depo_C PF06850.11 EGC34181.1 - 0.024 14.1 0.2 0.036 13.5 0.2 1.4 1 1 0 1 1 1 0 PHB de-polymerase C-terminus Ribosomal_L13 PF00572.18 EGC34182.1 - 1.4e-11 44.7 0.6 2.7e-09 37.3 0.1 2.8 3 1 0 3 3 3 1 Ribosomal protein L13 TP53IP5 PF15331.6 EGC34182.1 - 0.0088 16.2 0.1 0.016 15.4 0.1 1.4 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 Malate_synthase PF01274.22 EGC34183.1 - 2.9e-204 679.2 0.0 3.3e-204 679.0 0.0 1.0 1 0 0 1 1 1 1 Malate synthase Nas2_N PF18265.1 EGC34184.1 - 1.8e-24 85.4 0.2 4.1e-24 84.3 0.2 1.6 1 0 0 1 1 1 1 Nas2 N_terminal domain PDZ_6 PF17820.1 EGC34184.1 - 0.00012 21.8 0.0 0.0095 15.8 0.0 2.7 2 0 0 2 2 2 1 PDZ domain PDZ_2 PF13180.6 EGC34184.1 - 0.00042 20.6 0.0 0.0025 18.1 0.0 2.1 1 1 0 1 1 1 1 PDZ domain PHM7_cyt PF14703.6 EGC34184.1 - 0.023 14.9 1.0 0.037 14.3 1.0 1.4 1 0 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter DUF3573 PF12097.8 EGC34184.1 - 0.1 11.4 4.6 0.16 10.7 4.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) ABC_tran_CTD PF16326.5 EGC34184.1 - 0.1 12.8 3.9 0.2 12.0 0.8 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain DUF3800 PF12686.7 EGC34184.1 - 0.11 13.2 1.8 0.12 13.0 0.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) Jnk-SapK_ap_N PF09744.9 EGC34184.1 - 0.33 11.2 6.2 0.17 12.1 1.1 2.2 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 DUF4795 PF16043.5 EGC34184.1 - 0.45 10.1 5.9 0.73 9.4 5.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4795) Spectrin PF00435.21 EGC34184.1 - 0.53 10.8 4.9 2.4 8.7 3.9 2.1 1 1 0 1 1 1 0 Spectrin repeat Acetyltransf_1 PF00583.25 EGC34185.1 - 5.3e-14 52.5 0.0 8e-14 51.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC34185.1 - 4.7e-08 33.0 0.0 7.8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC34185.1 - 3.1e-07 30.7 0.0 5.1e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC34185.1 - 0.00051 20.0 0.0 0.0008 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Isy1 PF06246.12 EGC34185.1 - 0.0019 17.8 6.0 0.0033 17.0 6.0 1.4 1 0 0 1 1 1 1 Isy1-like splicing family CDC45 PF02724.14 EGC34185.1 - 0.046 12.0 4.7 0.047 12.0 4.7 1.1 1 0 0 1 1 1 0 CDC45-like protein CPSF100_C PF13299.6 EGC34185.1 - 0.099 12.8 4.5 0.13 12.5 4.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Acetyltransf_13 PF13880.6 EGC34185.1 - 0.13 12.3 0.1 0.31 11.0 0.1 1.7 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase GCD14 PF08704.10 EGC34185.1 - 0.23 11.1 3.3 0.29 10.8 3.3 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Peptidase_S49_N PF08496.10 EGC34185.1 - 2.1 8.4 7.1 3 7.9 7.1 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF2956 PF11169.8 EGC34185.1 - 2.3 8.4 9.9 4.5 7.5 9.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Connexin PF00029.19 EGC34185.1 - 2.7 7.7 5.6 4.1 7.1 5.6 1.3 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC34185.1 - 3.6 6.3 7.5 4.3 6.0 7.5 1.1 1 0 0 1 1 1 0 Presenilin GTP_EFTU PF00009.27 EGC34186.1 - 8.7e-26 90.7 0.1 3.4e-25 88.7 0.1 2.0 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGC34186.1 - 2.6e-20 72.5 1.6 4.6e-20 71.7 0.3 2.2 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGC34186.1 - 0.00011 22.5 0.3 0.00011 22.5 0.3 3.5 3 1 0 3 3 3 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC34186.1 - 0.0014 18.7 0.2 0.017 15.2 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.6 EGC34186.1 - 0.0079 16.1 2.1 0.052 13.5 0.3 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 4 DUF2678 PF10856.8 EGC34187.1 - 3.8e-05 23.6 0.7 5.9e-05 23.0 0.7 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2678) HlyIII PF03006.20 EGC34187.1 - 0.06 13.0 0.3 0.081 12.6 0.3 1.2 1 0 0 1 1 1 0 Haemolysin-III related DUF4131 PF13567.6 EGC34187.1 - 0.12 12.0 0.2 0.14 11.8 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) AMP-binding PF00501.28 EGC34188.1 - 1.4e-71 241.3 0.0 1.9e-71 240.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC34188.1 - 1.2e-15 57.2 5.4 1.7e-15 56.7 4.2 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC34188.1 - 9.3e-10 39.4 0.0 2.3e-09 38.1 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGC34189.1 - 1.1e-72 244.9 0.0 1.5e-72 244.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC34189.1 - 1.7e-16 59.9 3.6 4.8e-16 58.4 3.6 1.8 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC34189.1 - 5.2e-10 40.2 0.0 1.3e-09 38.8 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGC34190.1 - 1.3e-70 238.2 0.0 1.7e-70 237.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC34190.1 - 2.5e-16 59.3 3.1 7.3e-16 57.8 3.1 1.9 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC34190.1 - 3.2e-10 40.8 0.0 8.2e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.28 EGC34191.1 - 8.5e-73 245.3 0.0 1.1e-72 245.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC34191.1 - 4.7e-16 58.4 4.6 8.5e-16 57.6 3.6 2.1 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC34191.1 - 1.8e-10 41.6 0.0 4.6e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain zf-CCHC PF00098.23 EGC34193.1 - 1.9e-06 27.7 1.3 3.1e-06 27.0 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle FNIP PF05725.12 EGC34194.1 - 5.9e-239 772.2 145.7 2.9e-16 59.3 1.2 20.2 12 3 6 22 22 22 21 FNIP Repeat Phage_min_tail PF05939.13 EGC34194.1 - 2.9e-10 40.5 0.0 75 3.8 0.0 12.6 7 5 8 16 16 16 0 Phage minor tail protein DUF5615 PF18480.1 EGC34194.1 - 2.3 8.1 6.7 34 4.3 0.0 5.2 7 0 0 7 7 7 0 Domain of unknown function (DUF5615) FNIP PF05725.12 EGC34195.1 - 3.8e-81 267.0 59.0 1.4e-16 60.3 1.5 7.6 5 1 0 7 7 7 7 FNIP Repeat Phage_min_tail PF05939.13 EGC34195.1 - 0.12 12.8 0.0 42 4.6 0.0 3.7 4 0 0 4 4 4 0 Phage minor tail protein DUF2924 PF11149.8 EGC34196.1 - 2.6 8.4 12.7 3 8.2 12.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) K_trans PF02705.16 EGC34196.1 - 3.6 6.0 5.2 3.5 6.0 5.2 1.0 1 0 0 1 1 1 0 K+ potassium transporter T2SSC PF11356.8 EGC34196.1 - 7.9 6.4 11.0 4.4 7.2 9.4 1.5 1 1 1 2 2 2 0 Type II secretion system protein C TMEMspv1-c74-12 PF11044.8 EGC34197.1 - 0.052 13.5 0.8 0.08 12.9 0.8 1.3 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF4668 PF15701.5 EGC34197.1 - 0.27 11.1 5.1 0.34 10.7 5.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4668) Claudin_3 PF06653.11 EGC34197.1 - 1 9.3 5.8 1.5 8.7 5.8 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like WD40 PF00400.32 EGC34198.1 - 1.1e-13 51.4 5.2 0.00013 22.7 0.2 5.5 5 0 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34198.1 - 2.1e-07 31.2 0.0 0.006 16.9 0.0 3.3 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EGC34198.1 - 3.6e-06 26.5 1.0 4e-05 23.1 0.3 2.8 1 1 2 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF5496 PF17600.2 EGC34198.1 - 0.11 12.6 0.3 0.51 10.4 0.2 2.3 1 1 0 1 1 1 0 Family of unknown function (DUF5496) Insulin_TMD PF17870.1 EGC34198.1 - 0.14 12.2 3.2 0.5 10.5 3.2 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF_2 PF07974.13 EGC34198.1 - 0.2 12.1 10.3 0.61 10.5 10.3 1.9 1 0 0 1 1 1 0 EGF-like domain TMEM208_SND2 PF05620.11 EGC34199.1 - 1.5e-48 164.8 0.3 1.7e-48 164.6 0.3 1.0 1 0 0 1 1 1 1 SRP-independent targeting protein 2/TMEM208 Peptidase_M48_N PF16491.5 EGC34199.1 - 0.039 13.9 0.4 0.039 13.9 0.4 2.0 2 0 0 2 2 2 0 CAAX prenyl protease N-terminal, five membrane helices zf-RING_9 PF13901.6 EGC34200.1 - 5.6e-46 157.1 10.7 5.6e-46 157.1 10.7 2.1 2 0 0 2 2 2 1 Putative zinc-RING and/or ribbon RUN PF02759.19 EGC34200.1 - 1.1e-17 64.3 6.3 7.7e-16 58.3 0.3 3.5 3 0 0 3 3 3 2 RUN domain zf-RRN7 PF11781.8 EGC34200.1 - 1.4 8.7 5.0 1.4 8.7 0.9 2.6 2 0 0 2 2 2 0 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 zinc-ribbons_6 PF07191.12 EGC34200.1 - 1.6 8.8 8.5 0.39 10.7 0.7 2.8 2 0 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 EGC34200.1 - 6 6.9 11.5 0.17 11.9 3.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Ufm1 PF03671.14 EGC34201.1 - 8.8e-41 137.9 0.3 9.9e-41 137.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein GFA PF04828.14 EGC34202.1 - 2.2e-06 27.9 0.1 2.2e-06 27.9 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Fer4_23 PF18009.1 EGC34202.1 - 0.032 14.7 0.1 0.048 14.1 0.1 1.2 1 0 0 1 1 1 0 4Fe-4S iron-sulfur cluster binding domain Androgen_recep PF02166.16 EGC34203.1 - 0.48 9.2 1.8 0.68 8.7 1.8 1.1 1 0 0 1 1 1 0 Androgen receptor ketoacyl-synt PF00109.26 EGC34204.1 - 6.8e-64 215.9 0.0 1.1e-63 215.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34204.1 - 1.1e-43 149.9 0.0 2e-43 149.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGC34204.1 - 4.6e-38 130.9 0.0 7.9e-38 130.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC34204.1 - 1.6e-31 108.7 0.0 3.1e-31 107.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34204.1 - 3e-25 89.2 0.1 2.5e-21 76.4 0.0 3.4 3 0 0 3 3 3 1 KR domain KAsynt_C_assoc PF16197.5 EGC34204.1 - 4.6e-17 62.5 0.3 2.2e-16 60.3 0.1 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC34204.1 - 1.7e-14 53.7 0.0 2.7e-14 53.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC34204.1 - 7.1e-14 53.0 0.0 3.5e-13 50.8 0.0 2.2 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGC34204.1 - 5e-09 36.8 0.2 3.7e-08 34.0 0.1 2.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34204.1 - 1.6e-07 31.3 0.0 6.3e-07 29.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EGC34204.1 - 1.9e-07 30.9 0.1 4.4e-07 29.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC34204.1 - 2.8e-07 30.6 0.0 1e-05 25.5 0.0 2.9 3 0 0 3 3 3 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.12 EGC34204.1 - 0.00097 19.7 0.0 0.0032 18.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC34204.1 - 0.0012 18.3 0.0 0.0024 17.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGC34204.1 - 0.0031 17.8 0.1 0.008 16.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGC34204.1 - 0.0066 16.3 0.1 0.045 13.5 0.1 2.5 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.21 EGC34204.1 - 0.012 15.1 0.0 0.038 13.5 0.0 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ras PF00071.22 EGC34205.1 - 3.4e-35 121.0 0.3 4.1e-35 120.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34205.1 - 6.4e-26 90.9 0.1 1e-25 90.3 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34205.1 - 5.1e-08 32.6 0.1 6.3e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC34205.1 - 1.8e-06 27.5 0.3 2.2e-06 27.2 0.3 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region DLIC PF05783.11 EGC34205.1 - 0.0041 16.0 0.0 1.3 7.7 0.0 2.0 2 0 0 2 2 2 2 Dynein light intermediate chain (DLIC) G-alpha PF00503.20 EGC34205.1 - 0.0065 15.7 3.5 0.09 11.9 1.3 2.8 1 1 1 2 2 2 1 G-protein alpha subunit PduV-EutP PF10662.9 EGC34205.1 - 0.044 13.5 0.4 0.099 12.4 0.4 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGC34205.1 - 0.054 12.9 0.1 0.066 12.6 0.1 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit CENP-M PF11111.8 EGC34205.1 - 0.072 12.3 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 Centromere protein M (CENP-M) TniB PF05621.11 EGC34205.1 - 0.083 12.3 0.0 1.3 8.4 0.0 2.3 2 1 0 2 2 2 0 Bacterial TniB protein MMR_HSR1 PF01926.23 EGC34205.1 - 0.097 12.8 0.0 0.17 12.0 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Tyr_Deacylase PF02580.16 EGC34206.1 - 6.7e-51 172.6 0.0 8e-51 172.4 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PKD_channel PF08016.12 EGC34207.1 - 4.4e-10 38.8 9.9 6.7e-10 38.2 9.9 1.3 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.31 EGC34207.1 - 1.5e-06 27.6 18.8 1.5e-06 27.6 18.8 3.0 2 1 0 2 2 2 1 Ion transport protein Corazonin PF17308.2 EGC34207.1 - 7.2 7.0 25.7 1.1 9.6 14.6 3.8 4 0 0 4 4 4 0 Pro-corazonin LRR_8 PF13855.6 EGC34208.1 - 1.3e-19 69.7 38.9 1.2e-06 28.2 3.4 6.9 4 2 3 7 7 7 6 Leucine rich repeat LRR_4 PF12799.7 EGC34208.1 - 1.7e-06 28.3 60.2 0.027 14.9 3.2 10.1 5 3 7 12 12 12 8 Leucine Rich repeats (2 copies) Ephrin_rec_like PF07699.13 EGC34208.1 - 0.84 9.4 10.7 0.36 10.6 2.4 2.6 2 0 0 2 2 2 0 Putative ephrin-receptor like MFS_1 PF07690.16 EGC34209.1 - 3.8e-30 105.0 44.9 1.4e-26 93.2 29.5 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC34209.1 - 1.4e-05 24.2 2.7 1.4e-05 24.2 2.7 3.4 2 1 1 3 3 3 2 Sugar (and other) transporter Glutaredoxin PF00462.24 EGC34210.1 - 1.1e-05 25.5 0.0 3.5e-05 23.9 0.0 1.9 2 1 0 2 2 2 1 Glutaredoxin GA-like PF17573.2 EGC34210.1 - 0.039 13.9 0.0 0.21 11.5 0.0 2.1 2 0 0 2 2 2 0 GA-like domain Arfaptin PF06456.13 EGC34211.1 - 0.016 14.8 0.4 0.022 14.3 0.4 1.3 1 0 0 1 1 1 0 Arfaptin-like domain DUF2614 PF11023.8 EGC34211.1 - 0.24 11.5 4.6 0.37 10.9 4.6 1.2 1 0 0 1 1 1 0 Zinc-ribbon containing domain UQ_con PF00179.26 EGC34212.1 - 2.5e-48 163.3 0.3 2.8e-48 163.1 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC34212.1 - 0.00064 20.0 0.3 0.00085 19.6 0.3 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGC34212.1 - 0.0012 18.6 0.0 0.0014 18.3 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B UEV PF05743.13 EGC34212.1 - 0.0048 16.8 0.4 0.0092 15.8 0.4 1.5 1 1 0 1 1 1 1 UEV domain Erf4 PF10256.9 EGC34213.1 - 0.00043 20.4 1.9 0.0054 16.8 0.8 2.4 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family TFIIA PF03153.13 EGC34213.1 - 3.2 7.6 19.1 4.1 7.3 19.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PHD PF00628.29 EGC34214.1 - 9.6e-07 28.6 7.7 9.6e-07 28.6 7.7 4.7 3 1 1 4 4 4 1 PHD-finger SSP160 PF06933.11 EGC34214.1 - 0.81 7.8 16.5 1.1 7.3 16.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC34214.1 - 7 6.6 27.6 12 5.8 27.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein PHD_4 PF16866.5 EGC34214.1 - 9.4 6.4 14.2 0.081 13.0 3.4 3.3 3 0 0 3 3 3 0 PHD-finger LIM PF00412.22 EGC34216.1 - 1.5e-29 102.0 37.7 3.7e-12 46.3 5.1 3.2 3 0 0 3 3 3 3 LIM domain WH2 PF02205.20 EGC34216.1 - 2.2e-08 33.7 0.1 1.8e-07 30.8 0.1 2.4 2 0 0 2 2 2 1 WH2 motif Thymosin PF01290.20 EGC34216.1 - 0.00017 21.3 0.1 0.00034 20.3 0.1 1.5 1 0 0 1 1 1 1 Thymosin beta-4 family Pkinase PF00069.25 EGC34217.1 - 1.5e-63 214.7 0.0 2.8e-63 213.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34217.1 - 5.6e-49 166.8 0.0 8.3e-49 166.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC34217.1 - 0.0043 15.9 0.0 0.0043 15.9 0.0 2.0 3 0 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGC34217.1 - 0.023 14.0 0.0 0.045 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like MSP1_C PF07462.11 EGC34217.1 - 0.025 13.3 2.5 0.12 11.1 2.7 1.8 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus DUF3450 PF11932.8 EGC34217.1 - 0.031 13.6 0.1 0.031 13.6 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) IF-2B PF01008.17 EGC34218.1 - 2.3e-78 263.3 0.4 3.1e-78 262.8 0.4 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family Death PF00531.22 EGC34218.1 - 0.0046 17.1 0.1 0.038 14.1 0.0 2.2 2 0 0 2 2 2 1 Death domain DUF515 PF04415.12 EGC34218.1 - 0.018 13.4 1.7 0.023 13.1 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Med3 PF11593.8 EGC34218.1 - 0.032 13.4 7.2 0.045 13.0 4.1 2.0 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal DUF2464 PF10240.9 EGC34218.1 - 0.043 13.4 0.2 0.061 12.9 0.2 1.2 1 0 0 1 1 1 0 Multivesicular body subunit 12 Peptidase_M44 PF03410.13 EGC34218.1 - 0.13 10.9 0.1 0.17 10.4 0.1 1.1 1 0 0 1 1 1 0 Metallopeptidase from vaccinia pox Kinesin_assoc PF16183.5 EGC34218.1 - 0.73 10.0 4.5 9.4 6.3 0.5 2.2 2 0 0 2 2 2 0 Kinesin-associated Frizzled PF01534.17 EGC34219.1 - 2.6e-06 26.7 15.6 5.7e-06 25.6 15.6 1.6 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGC34219.1 - 1.1e-05 24.9 12.7 1.1e-05 24.9 12.7 1.8 1 1 0 2 2 2 1 7 transmembrane receptor (Secretin family) S_layer_C PF05124.12 EGC34220.1 - 0.048 13.7 0.2 2 8.3 0.0 2.1 2 0 0 2 2 2 0 S-layer like family, C-terminal region YAcAr PF10686.9 EGC34220.1 - 0.095 12.7 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 YspA, cpYpsA-related SLOG family DUF1741 PF08427.10 EGC34221.1 - 1e-70 238.0 0.7 6.6e-70 235.4 0.2 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Histone PF00125.24 EGC34222.1 - 0.25 11.7 4.3 19 5.6 0.0 2.6 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Adaptin_N PF01602.20 EGC34223.1 - 2.2e-141 472.0 14.2 2.7e-141 471.7 14.2 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.20 EGC34223.1 - 1.2e-25 90.0 1.9 1.2e-25 90.0 1.9 2.6 3 1 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.7 EGC34223.1 - 3.1e-08 33.8 13.8 7.3e-07 29.4 0.1 3.5 3 1 1 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGC34223.1 - 0.0055 16.9 0.1 1 9.8 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.6 EGC34223.1 - 0.01 16.2 0.2 0.76 10.2 0.1 3.0 3 0 0 3 3 3 0 HEAT repeats Proteasom_PSMB PF10508.9 EGC34223.1 - 0.051 12.1 3.6 0.2 10.1 3.6 2.0 1 0 0 1 1 1 0 Proteasome non-ATPase 26S subunit Cohesin_HEAT PF12765.7 EGC34223.1 - 0.07 13.4 0.1 0.2 12.0 0.1 1.9 1 0 0 1 1 1 0 HEAT repeat associated with sister chromatid cohesion TIP120 PF08623.10 EGC34223.1 - 0.21 11.3 5.9 1.7 8.4 0.1 3.4 3 0 0 3 3 3 0 TATA-binding protein interacting (TIP20) FNIP PF05725.12 EGC34224.1 - 1.6e-37 127.4 16.8 4.3e-11 42.8 0.1 4.5 4 0 0 4 4 4 4 FNIP Repeat RhoGEF PF00621.20 EGC34225.1 - 1e-51 175.7 6.1 1e-51 175.7 6.1 3.0 3 0 0 3 3 3 1 RhoGEF domain Terpene_synth_C PF03936.16 EGC34225.1 - 1.2e-06 28.1 1.6 2.6e-06 27.0 1.6 1.6 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Nup35_RRM PF05172.13 EGC34225.1 - 0.035 14.1 1.1 0.13 12.3 0.4 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif DUF4969 PF16339.5 EGC34225.1 - 0.22 11.9 1.9 0.76 10.2 1.9 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4969) PI3_PI4_kinase PF00454.27 EGC34226.1 - 3.5e-48 164.6 0.3 8.7e-47 160.0 0.1 3.2 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC34226.1 - 4.8e-42 143.5 6.3 4.8e-42 143.5 6.3 2.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.24 EGC34226.1 - 8.9e-12 45.1 0.6 8.9e-12 45.1 0.6 2.5 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DKCLD PF08068.12 EGC34227.1 - 6.1e-35 119.1 0.5 4.3e-33 113.2 0.7 2.7 2 0 0 2 2 2 1 DKCLD (NUC011) domain PUA PF01472.20 EGC34227.1 - 1.3e-21 76.3 1.1 2.8e-21 75.3 1.1 1.6 1 0 0 1 1 1 1 PUA domain TruB_C_2 PF16198.5 EGC34227.1 - 1.8e-21 76.0 0.2 3.8e-21 75.0 0.2 1.6 1 0 0 1 1 1 1 tRNA pseudouridylate synthase B C-terminal domain TruB_N PF01509.18 EGC34227.1 - 1.1e-18 68.0 10.5 2.2e-18 67.0 0.3 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) UPF0113 PF03657.13 EGC34227.1 - 0.0011 19.1 0.0 0.0034 17.6 0.0 1.9 1 0 0 1 1 1 1 UPF0113 PUA domain CDC27 PF09507.10 EGC34227.1 - 1.3 8.3 57.5 0.019 14.4 45.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 SID-1_RNA_chan PF13965.6 EGC34227.1 - 3.9 5.8 6.5 6.1 5.1 6.5 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LRR_4 PF12799.7 EGC34228.1 - 8e-05 22.9 12.5 0.0041 17.5 2.4 3.1 1 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC34228.1 - 0.0003 20.5 9.0 0.031 14.0 5.7 2.3 1 1 1 2 2 2 2 Leucine rich repeat FNIP PF05725.12 EGC34228.1 - 0.0017 18.5 1.0 0.081 13.1 0.1 2.7 1 1 1 2 2 2 2 FNIP Repeat LRR_1 PF00560.33 EGC34228.1 - 0.0017 18.6 8.7 0.84 10.4 1.3 3.8 2 2 1 3 3 3 3 Leucine Rich Repeat Alpha-amylase PF00128.24 EGC34229.1 - 1.9e-81 274.2 0.0 4.4e-81 273.1 0.0 1.5 1 1 0 1 1 1 1 Alpha amylase, catalytic domain Malt_amylase_C PF16657.5 EGC34229.1 - 1.5e-08 34.6 0.1 0.00012 22.1 0.0 3.1 3 0 0 3 3 3 2 Maltogenic Amylase, C-terminal domain Glyco_hydro_70 PF02324.16 EGC34229.1 - 0.0048 15.2 0.4 0.13 10.4 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 RTC PF01137.21 EGC34230.1 - 3.2e-61 206.4 0.0 3.6e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGC34230.1 - 2.9e-33 114.4 0.0 4.7e-33 113.8 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain HTH_29 PF13551.6 EGC34230.1 - 0.11 12.5 0.0 0.6 10.2 0.0 2.0 2 0 0 2 2 2 0 Winged helix-turn helix SPT16 PF08644.11 EGC34231.1 - 1.5e-48 164.8 0.2 1.5e-48 164.8 0.2 3.7 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.6 EGC34231.1 - 1.9e-40 138.3 2.1 1.9e-40 138.3 2.1 2.8 2 1 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.24 EGC34231.1 - 4.7e-34 117.9 0.0 7.1e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.12 EGC34231.1 - 1.3e-13 51.1 0.2 4.1e-13 49.5 0.2 1.9 1 0 0 1 1 1 1 Histone chaperone Rttp106-like DNA_pol_A PF00476.20 EGC34232.1 - 6.4e-84 282.2 6.4 1.2e-83 281.3 6.4 1.4 1 0 0 1 1 1 1 DNA polymerase family A RasGEF PF00617.19 EGC34233.1 - 4.9e-47 160.4 4.3 4.9e-47 160.4 4.3 2.2 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC34233.1 - 3.1e-16 59.5 1.4 3.1e-16 59.5 1.4 4.0 5 0 0 5 5 5 1 RasGEF N-terminal motif cNMP_binding PF00027.29 EGC34233.1 - 2.2e-13 50.1 0.1 0.00042 20.3 0.0 4.3 3 1 0 3 3 3 3 Cyclic nucleotide-binding domain GRAM PF02893.20 EGC34233.1 - 2.8e-07 30.4 2.0 6.1e-07 29.3 0.3 2.6 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.20 EGC34235.1 - 2.6e-28 98.5 1.5 3.4e-28 98.1 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC34235.1 - 0.00067 19.3 1.2 0.0011 18.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase C1_4 PF07975.12 EGC34235.1 - 0.01 16.0 1.4 0.063 13.5 0.2 2.5 2 0 0 2 2 2 0 TFIIH C1-like domain CDK2AP PF09806.9 EGC34235.1 - 0.022 14.8 5.0 0.031 14.3 5.0 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein RNA_pol_N PF01194.17 EGC34235.1 - 0.035 14.4 1.1 0.74 10.2 0.1 3.2 3 0 0 3 3 3 0 RNA polymerases N / 8 kDa subunit Nop14 PF04147.12 EGC34235.1 - 0.079 11.2 21.8 0.1 10.8 21.8 1.1 1 0 0 1 1 1 0 Nop14-like family PTPlike_phytase PF14566.6 EGC34235.1 - 0.1 12.7 0.0 0.1 12.7 0.0 2.6 2 1 0 2 2 1 0 Inositol hexakisphosphate zf-C2H2_3rep PF18868.1 EGC34235.1 - 0.17 12.6 2.7 0.17 12.5 0.4 2.1 1 1 1 2 2 2 0 Zinc finger C2H2-type, 3 repeats YL1 PF05764.13 EGC34235.1 - 0.18 11.9 18.3 0.24 11.5 18.3 1.2 1 0 0 1 1 1 0 YL1 nuclear protein PI3K_1B_p101 PF10486.9 EGC34235.1 - 0.22 9.3 15.9 0.3 8.8 15.9 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Yippee-Mis18 PF03226.14 EGC34235.1 - 0.36 11.1 4.5 0.8 9.9 2.7 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LMBR1 PF04791.16 EGC34235.1 - 0.75 8.6 6.7 0.92 8.3 6.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Lin-8 PF03353.15 EGC34235.1 - 0.94 9.0 19.3 1.5 8.3 19.3 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist CDC45 PF02724.14 EGC34235.1 - 1.8 6.8 17.9 2.5 6.3 17.9 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.10 EGC34235.1 - 2 7.7 22.2 2.8 7.2 22.2 1.2 1 0 0 1 1 1 0 BUD22 SLC12 PF03522.15 EGC34235.1 - 4.7 6.1 10.6 8.8 5.2 10.6 1.4 1 0 0 1 1 1 0 Solute carrier family 12 Presenilin PF01080.17 EGC34235.1 - 4.8 5.9 12.6 7.6 5.2 12.6 1.3 1 0 0 1 1 1 0 Presenilin TFIIF_alpha PF05793.12 EGC34235.1 - 7.3 5.1 33.3 11 4.5 33.3 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Erf4 PF10256.9 EGC34236.1 - 0.0023 18.0 0.6 0.0062 16.6 0.2 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4191 PF13829.6 EGC34236.1 - 0.021 14.2 1.8 0.03 13.7 1.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4337 PF14235.6 EGC34236.1 - 0.25 11.4 0.6 0.45 10.6 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Pkinase PF00069.25 EGC34237.1 - 3.1e-22 79.2 0.0 3.1e-22 79.2 0.0 2.4 3 0 0 3 3 3 1 Protein kinase domain WD40 PF00400.32 EGC34237.1 - 1.5e-15 57.3 1.6 0.00036 21.3 0.1 5.7 5 0 0 5 5 5 3 WD domain, G-beta repeat Pkinase_Tyr PF07714.17 EGC34237.1 - 3.3e-10 39.7 0.0 9.3e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EGC34237.1 - 1.1e-06 28.4 2.9 0.044 14.1 0.1 5.3 5 0 0 5 5 5 2 HEAT repeat APH PF01636.23 EGC34237.1 - 0.072 13.0 0.0 0.072 13.0 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.20 EGC34238.1 - 1.4e-47 162.3 4.7 1.4e-47 162.3 4.7 2.8 2 0 0 2 2 2 1 RhoGEF domain PX PF00787.24 EGC34238.1 - 2.5e-18 66.1 1.6 2.5e-18 66.1 1.6 2.4 3 0 0 3 3 3 1 PX domain CH PF00307.31 EGC34238.1 - 5.1e-08 33.1 0.1 5.1e-08 33.1 0.1 2.5 2 1 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.27 EGC34238.1 - 0.26 11.2 0.5 0.99 9.4 0.5 2.0 1 0 0 1 1 1 0 IQ calmodulin-binding motif Cyt-b5 PF00173.28 EGC34240.1 - 8e-13 48.3 0.0 9.6e-13 48.1 0.0 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain GIIM PF08388.11 EGC34240.1 - 0.079 13.0 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Group II intron, maturase-specific domain DUF4020 PF13212.6 EGC34240.1 - 0.08 12.8 0.3 0.13 12.1 0.0 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) Sec3-PIP2_bind PF15277.6 EGC34240.1 - 0.13 12.4 0.0 0.39 10.9 0.0 1.7 2 0 0 2 2 2 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Kelch_1 PF01344.25 EGC34241.1 - 1.7e-35 120.4 25.4 2.1e-10 40.0 0.3 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGC34241.1 - 2.6e-32 110.0 22.1 2.6e-06 27.5 1.1 6.3 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGC34241.1 - 2e-30 104.3 24.2 5.5e-07 29.4 0.3 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC34241.1 - 4.3e-29 100.2 14.9 2.5e-09 37.2 0.1 7.4 7 1 0 7 7 7 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC34241.1 - 3.9e-25 86.8 16.4 1.4e-05 24.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC34241.1 - 7.5e-24 83.5 15.2 5.5e-06 26.3 1.4 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain F-box-like PF12937.7 EGC34241.1 - 7e-10 38.6 0.1 2.1e-09 37.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC34241.1 - 5.3e-05 23.0 0.7 5.3e-05 23.0 0.7 2.1 2 0 0 2 2 2 1 F-box domain F-box_4 PF15966.5 EGC34241.1 - 0.023 14.6 1.1 0.029 14.3 0.0 1.7 2 0 0 2 2 2 0 F-box RNA_pol_Rpc34 PF05158.12 EGC34242.1 - 9.7e-57 192.9 2.5 1.1e-40 140.1 1.8 2.2 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.12 EGC34242.1 - 6.4e-05 23.0 0.5 0.00013 22.1 0.2 1.7 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC EF-hand_9 PF14658.6 EGC34242.1 - 0.0035 17.6 0.1 0.021 15.2 0.0 2.2 2 0 0 2 2 2 1 EF-hand domain RPA_C PF08784.11 EGC34242.1 - 0.0039 17.8 0.2 1.7 9.4 0.1 2.4 1 1 1 2 2 2 2 Replication protein A C terminal TrmB PF01978.19 EGC34242.1 - 0.017 15.0 0.1 0.62 10.0 0.1 2.3 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PYC_OADA PF02436.18 EGC34242.1 - 0.1 12.3 0.1 0.31 10.7 0.1 1.7 2 0 0 2 2 2 0 Conserved carboxylase domain Cyclin_C PF02984.19 EGC34242.1 - 0.11 12.6 0.2 0.33 11.0 0.1 1.8 2 0 0 2 2 2 0 Cyclin, C-terminal domain Type2_restr_D3 PF16902.5 EGC34242.1 - 0.15 12.0 1.7 0.62 10.0 0.2 2.3 2 0 0 2 2 2 0 Type-2 restriction enzyme D3 domain GHMP_kinases_N PF00288.26 EGC34243.1 - 1.5e-15 57.2 0.2 2.9e-15 56.2 0.2 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGC34243.1 - 1.8e-07 31.4 0.0 5.5e-07 29.9 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal Actin PF00022.19 EGC34244.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin AAA PF00004.29 EGC34245.1 - 2.1e-50 170.5 0.1 5.2e-39 133.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC34245.1 - 1e-10 41.3 0.0 9.3e-06 25.4 0.0 2.7 3 0 0 3 3 3 2 AAA+ lid domain TIP49 PF06068.13 EGC34245.1 - 2.4e-06 27.0 0.0 0.00024 20.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain Rad17 PF03215.15 EGC34245.1 - 6.7e-06 26.1 3.7 0.018 15.0 0.1 3.3 2 2 1 3 3 3 2 Rad17 P-loop domain AAA_16 PF13191.6 EGC34245.1 - 2.3e-05 24.8 0.1 0.00061 20.2 0.0 2.9 2 2 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGC34245.1 - 2.9e-05 23.4 0.0 0.0012 18.1 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGC34245.1 - 0.0012 19.2 0.1 0.0068 16.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_5 PF07728.14 EGC34245.1 - 0.0016 18.4 0.0 0.093 12.7 0.0 3.6 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EGC34245.1 - 0.0038 17.7 0.1 0.0038 17.7 0.1 2.6 2 1 1 3 3 2 1 ABC transporter AAA_7 PF12775.7 EGC34245.1 - 0.0043 16.6 0.3 0.095 12.2 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_2 PF07724.14 EGC34245.1 - 0.0052 16.9 0.0 0.016 15.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_14 PF13173.6 EGC34245.1 - 0.0084 16.1 0.0 0.0084 16.1 0.0 3.1 3 1 0 3 3 2 1 AAA domain AAA_29 PF13555.6 EGC34245.1 - 0.01 15.6 0.2 0.031 14.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC34245.1 - 0.011 15.7 0.2 1.2 9.1 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase Cytidylate_kin PF02224.18 EGC34245.1 - 0.023 14.4 0.0 2 8.1 0.0 2.4 2 0 0 2 2 2 0 Cytidylate kinase AAA_22 PF13401.6 EGC34245.1 - 0.11 12.8 2.4 1.2 9.4 0.1 3.1 2 2 0 3 3 3 0 AAA domain Viral_helicase1 PF01443.18 EGC34245.1 - 0.13 12.0 0.0 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DcpS_C PF11969.8 EGC34247.1 - 1.5e-27 96.3 1.1 2.9e-27 95.4 1.1 1.5 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.23 EGC34247.1 - 9.6e-15 55.1 1.1 2.2e-14 53.9 0.1 2.1 2 0 0 2 2 2 1 HIT domain FHA_2 PF17913.1 EGC34247.1 - 6.6e-05 23.1 0.1 0.0016 18.7 0.1 2.7 1 1 0 1 1 1 1 FHA domain eIF-4B PF06273.11 EGC34247.1 - 0.021 13.9 1.8 0.029 13.4 1.8 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B zf-C2HE PF16278.5 EGC34247.1 - 0.058 13.9 0.3 0.058 13.9 0.3 2.6 2 1 0 2 2 2 0 C2HE / C2H2 / C2HC zinc-binding finger Folate_carrier PF01770.18 EGC34247.1 - 0.21 10.3 1.6 0.3 9.8 1.6 1.2 1 0 0 1 1 1 0 Reduced folate carrier DUF4637 PF15470.6 EGC34247.1 - 1.1 8.9 4.7 2 8.1 4.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF1764 PF08576.10 EGC34247.1 - 8.4 7.4 12.4 1.4 9.9 8.3 1.8 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF1764) NAD_kinase PF01513.21 EGC34248.1 - 2.6e-55 187.7 0.1 4.1e-55 187.0 0.1 1.3 1 1 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.24 EGC34248.1 - 0.03 13.9 0.0 0.051 13.2 0.0 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain HicA_toxin PF07927.12 EGC34248.1 - 0.072 13.1 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 HicA toxin of bacterial toxin-antitoxin, FNIP PF05725.12 EGC34249.1 - 2.6e-32 110.7 66.1 1.2e-07 31.8 0.3 11.0 8 1 2 10 10 10 7 FNIP Repeat LRR_1 PF00560.33 EGC34249.1 - 3.9 8.4 8.1 83 4.4 0.4 6.3 6 0 0 6 6 6 0 Leucine Rich Repeat RF-1 PF00472.20 EGC34250.1 - 1.9e-18 66.5 2.4 2.3e-18 66.2 2.4 1.1 1 0 0 1 1 1 1 RF-1 domain Colicin PF01024.19 EGC34250.1 - 0.013 15.4 0.0 0.021 14.7 0.0 1.4 1 0 0 1 1 1 0 Colicin pore forming domain TetR_C_29 PF17938.1 EGC34250.1 - 0.1 12.7 0.1 0.16 12.1 0.1 1.2 1 0 0 1 1 1 0 Tetracyclin repressor-like, C-terminal domain AhpC-TSA PF00578.21 EGC34251.1 - 1.6e-28 99.1 0.1 2e-28 98.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC34251.1 - 5.8e-16 58.5 0.0 6.7e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.6 EGC34251.1 - 0.00033 20.7 0.0 0.00047 20.2 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.6 EGC34251.1 - 0.032 14.6 0.1 0.048 14.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin-like SCO1-SenC PF02630.14 EGC34251.1 - 0.039 13.9 0.1 0.06 13.3 0.1 1.3 1 0 0 1 1 1 0 SCO1/SenC RasGEF PF00617.19 EGC34252.1 - 7.3e-55 185.9 2.2 7.3e-55 185.9 2.2 2.8 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.20 EGC34252.1 - 8.6e-17 61.3 3.9 2e-16 60.1 1.0 5.7 4 1 1 5 5 5 2 RasGEF N-terminal motif F-box-like PF12937.7 EGC34252.1 - 4.7e-14 52.0 8.1 1.2e-07 31.5 0.9 3.6 3 0 0 3 3 3 2 F-box-like F-box PF00646.33 EGC34252.1 - 8.7e-08 31.9 4.2 1.3e-05 25.0 1.2 3.5 3 0 0 3 3 3 2 F-box domain hNIFK_binding PF12196.8 EGC34252.1 - 4.4 6.9 11.5 9.3 5.8 0.0 3.7 3 0 0 3 3 3 0 FHA Ki67 binding domain of hNIFK Ank_2 PF12796.7 EGC34253.1 - 7.4e-35 119.4 12.1 2.1e-10 41.0 0.1 5.1 3 1 2 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC34253.1 - 3.9e-32 110.2 3.8 1.6e-06 28.5 0.0 6.0 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EGC34253.1 - 9e-25 86.0 5.3 0.0013 19.0 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.6 EGC34253.1 - 2.6e-23 79.6 5.9 0.00087 19.6 0.0 9.2 7 2 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.6 EGC34253.1 - 2.7e-21 75.3 2.3 1.5e-05 25.2 0.0 6.7 4 2 2 6 6 6 4 Ankyrin repeats (many copies) F-box-like PF12937.7 EGC34253.1 - 5.3e-09 35.8 4.3 1.1e-08 34.8 4.3 1.6 1 0 0 1 1 1 1 F-box-like SH2 PF00017.24 EGC34253.1 - 2.6e-07 30.6 0.0 1.2e-06 28.5 0.0 2.2 1 0 0 1 1 1 1 SH2 domain F-box PF00646.33 EGC34253.1 - 1.5e-06 27.9 2.8 1.5e-06 27.9 2.8 2.1 2 0 0 2 2 2 1 F-box domain Period_C PF12114.8 EGC34253.1 - 2.8 7.5 10.8 5.9 6.4 10.8 1.5 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Lipase_GDSL PF00657.22 EGC34254.1 - 5.6e-11 42.8 0.0 9.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.17 EGC34254.1 - 9.5e-09 35.2 1.9 2e-08 34.2 0.4 2.4 2 0 0 2 2 2 1 Saposin-like type B, region 2 Lipase_GDSL_2 PF13472.6 EGC34254.1 - 1.4e-05 25.5 0.1 2.7e-05 24.6 0.1 1.4 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Cu-binding_MopE PF11617.8 EGC34254.1 - 0.00034 20.7 1.7 0.0011 19.1 1.7 1.9 1 0 0 1 1 1 1 Putative metal-binding motif PALP PF00291.25 EGC34255.1 - 5.6e-63 213.1 0.0 6.3e-63 212.9 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.32 EGC34256.1 - 9.2e-17 61.1 17.3 0.29 12.1 0.3 10.6 10 0 0 10 10 10 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34256.1 - 5.8e-10 39.3 0.5 1.1 9.6 0.0 7.0 6 2 1 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGC34256.1 - 0.00033 19.8 1.0 1.3 8.0 0.0 4.0 4 0 0 4 4 4 3 Coatomer WD associated region eIF2A PF08662.11 EGC34256.1 - 4.9 7.0 6.0 15 5.4 0.2 4.0 5 0 0 5 5 5 0 Eukaryotic translation initiation factor eIF2A FNIP PF05725.12 EGC34257.1 - 1.5e-67 223.5 75.1 1.2e-10 41.4 0.0 14.5 10 3 5 15 15 15 13 FNIP Repeat LRR_8 PF13855.6 EGC34257.1 - 4.9 7.0 12.1 0.52 10.1 0.6 3.7 2 1 1 3 3 3 0 Leucine rich repeat PTR2 PF00854.21 EGC34258.1 - 3.9e-96 322.3 8.9 3.9e-96 322.3 8.9 1.4 1 1 0 1 1 1 1 POT family DUF4212 PF13937.6 EGC34258.1 - 0.044 14.2 10.7 2.1 8.8 1.8 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4212) DUF4149 PF13664.6 EGC34258.1 - 1.9 8.9 6.4 2.4 8.5 2.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF4231 PF14015.6 EGC34258.1 - 4.7 7.7 9.8 3.7 8.1 1.3 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Phage_holin_3_6 PF07332.11 EGC34258.1 - 9.1 6.4 7.3 6.7 6.8 0.2 3.3 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Ost4 PF10215.9 EGC34258.1 - 9.8 6.1 8.7 0.78 9.6 2.2 2.5 2 0 0 2 2 2 0 Oligosaccaryltransferase PTR2 PF00854.21 EGC34259.1 - 1.4e-98 330.3 9.0 1.4e-98 330.3 9.0 1.7 1 1 1 2 2 2 1 POT family Sugar_tr PF00083.24 EGC34259.1 - 0.39 9.5 29.9 0.076 11.9 10.3 2.6 2 1 0 2 2 2 0 Sugar (and other) transporter DUF3487 PF11990.8 EGC34259.1 - 3.8 7.4 6.4 3.3 7.6 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) CBFD_NFYB_HMF PF00808.23 EGC34260.1 - 1.6e-11 44.3 0.0 2.5e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone SprA-related PF12118.8 EGC34260.1 - 0.0004 19.6 4.6 0.00042 19.6 4.6 1.1 1 0 0 1 1 1 1 SprA-related family HTH_25 PF13413.6 EGC34260.1 - 0.015 15.1 0.1 0.045 13.6 0.0 1.7 2 0 0 2 2 2 0 Helix-turn-helix domain DUF913 PF06025.12 EGC34260.1 - 0.021 13.9 3.4 0.022 13.8 3.4 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) RR_TM4-6 PF06459.12 EGC34260.1 - 0.043 13.7 10.3 0.045 13.6 10.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF3744 PF12558.8 EGC34260.1 - 0.044 14.5 3.1 0.1 13.4 2.9 1.9 1 1 0 1 1 1 0 ATP-binding cassette cobalt transporter CPSF100_C PF13299.6 EGC34260.1 - 0.048 13.8 6.1 0.055 13.6 6.1 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Bromo_TP PF07524.13 EGC34260.1 - 0.069 13.2 0.0 0.11 12.6 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated Histone PF00125.24 EGC34260.1 - 0.075 13.4 9.8 0.15 12.4 0.0 2.1 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 Pox_Ag35 PF03286.14 EGC34260.1 - 0.12 12.1 16.3 0.17 11.7 16.3 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Presenilin PF01080.17 EGC34260.1 - 0.31 9.8 4.6 0.28 9.9 4.6 1.1 1 0 0 1 1 1 0 Presenilin RNA_pol_Rpc4 PF05132.14 EGC34260.1 - 0.33 11.4 7.4 0.38 11.2 7.4 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sporozoite_P67 PF05642.11 EGC34260.1 - 0.34 8.9 7.7 0.41 8.7 7.7 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Afi1 PF07792.12 EGC34260.1 - 0.43 11.1 14.4 0.58 10.6 14.4 1.2 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Peptidase_S49_N PF08496.10 EGC34260.1 - 0.47 10.5 7.7 0.56 10.3 7.7 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SID-1_RNA_chan PF13965.6 EGC34260.1 - 0.53 8.6 1.7 0.47 8.8 1.7 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 NOA36 PF06524.12 EGC34260.1 - 0.75 9.1 15.5 0.89 8.8 15.5 1.2 1 0 0 1 1 1 0 NOA36 protein CSRNP_N PF16019.5 EGC34260.1 - 0.78 9.6 8.0 0.89 9.4 8.0 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus Slu7 PF11708.8 EGC34260.1 - 0.85 9.3 21.5 1 9.0 21.5 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing Prp18-interacting factor CobT PF06213.12 EGC34260.1 - 1.5 8.1 18.0 1.9 7.8 18.0 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4820 PF16091.5 EGC34260.1 - 2.2 7.6 11.5 2 7.7 10.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4820) DUF2076 PF09849.9 EGC34260.1 - 2.3 8.2 12.2 2.5 8.1 12.2 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DNA_pol_phi PF04931.13 EGC34260.1 - 2.7 6.0 23.5 2.9 5.9 23.5 1.1 1 0 0 1 1 1 0 DNA polymerase phi GCD14 PF08704.10 EGC34260.1 - 4.5 6.9 8.0 6.2 6.4 8.0 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Vfa1 PF08432.10 EGC34260.1 - 6.4 7.1 22.3 8 6.8 22.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 ORC_WH_C PF18137.1 EGC34260.1 - 8.9 6.4 14.4 13 5.8 14.4 1.3 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal Phospholip_B PF04916.13 EGC34261.1 - 2.2e-142 475.3 9.5 2.5e-142 475.2 9.5 1.0 1 0 0 1 1 1 1 Phospholipase B Baculo_19 PF04798.12 EGC34262.1 - 0.13 12.0 2.1 1.1 9.0 0.4 2.0 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region Ribosomal_L37 PF08561.10 EGC34263.1 - 0.025 15.1 0.4 0.066 13.7 0.4 1.7 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L37 GATase_7 PF13537.6 EGC34264.1 - 1.1e-06 28.5 0.0 2.9e-06 27.2 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain Asn_synthase PF00733.21 EGC34264.1 - 6e-06 26.2 0.0 0.0011 18.7 0.0 2.4 2 0 0 2 2 2 2 Asparagine synthase GATase_6 PF13522.6 EGC34264.1 - 0.0045 17.2 0.0 0.01 16.0 0.0 1.6 1 1 0 1 1 1 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.20 EGC34264.1 - 0.063 13.0 0.0 0.18 11.6 0.0 1.8 2 0 0 2 2 2 0 PP-loop family QueC PF06508.13 EGC34264.1 - 0.078 12.5 0.5 0.23 10.9 0.0 1.9 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF5357 PF17310.2 EGC34264.1 - 0.091 11.3 0.3 0.15 10.6 0.3 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) MRPL52 PF18699.1 EGC34265.1 - 2.9e-25 88.3 4.2 3.8e-25 87.9 4.2 1.2 1 0 0 1 1 1 1 Mitoribosomal protein mL52 DUF763 PF05559.11 EGC34265.1 - 0.021 14.1 1.8 0.026 13.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) LRR_6 PF13516.6 EGC34266.1 - 2.1e-12 46.0 29.1 0.00026 20.8 0.4 8.5 9 0 0 9 9 9 4 Leucine Rich repeat LRR_1 PF00560.33 EGC34266.1 - 3e-07 30.0 21.2 3.1 8.7 0.1 9.1 10 0 0 10 10 10 4 Leucine Rich Repeat LRR_4 PF12799.7 EGC34266.1 - 1.8e-05 25.0 20.6 1.8 9.1 0.1 7.5 6 2 1 7 7 7 4 Leucine Rich repeats (2 copies) Carm_PH PF17888.1 EGC34266.1 - 0.00065 20.0 0.0 0.0019 18.5 0.0 1.8 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_8 PF13855.6 EGC34266.1 - 0.037 13.8 20.0 1.2 9.0 0.2 6.2 5 2 0 5 5 5 0 Leucine rich repeat WD40 PF00400.32 EGC34267.1 - 9.6e-09 35.8 4.1 0.63 11.0 0.0 5.9 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34267.1 - 0.0024 18.1 0.0 0.3 11.4 0.0 3.4 3 2 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Plk4_PB1 PF18190.1 EGC34267.1 - 0.087 13.0 0.0 0.3 11.3 0.0 2.0 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 1 PITH PF06201.13 EGC34268.1 - 3.1e-36 124.9 0.0 3.8e-36 124.6 0.0 1.1 1 0 0 1 1 1 1 PITH domain PLDc PF00614.22 EGC34269.1 - 1.9e-20 72.2 1.2 4.3e-10 39.3 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.6 EGC34269.1 - 5.9e-14 52.1 7.1 2e-08 34.2 0.5 3.1 3 0 0 3 3 3 2 PLD-like domain Arm PF00514.23 EGC34270.1 - 2.3e-23 81.4 3.2 4.9e-07 29.6 0.0 8.0 8 1 1 9 9 9 5 Armadillo/beta-catenin-like repeat FAM176 PF14851.6 EGC34270.1 - 0.38 10.4 12.1 1 9.0 0.0 2.4 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EGC34270.1 - 0.59 8.4 11.3 0.8 7.9 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein RXT2_N PF08595.11 EGC34270.1 - 8.1 6.5 10.7 16 5.5 10.7 1.5 1 0 0 1 1 1 0 RXT2-like, N-terminal ANAPC8 PF04049.13 EGC34271.1 - 8e-32 110.2 2.4 8e-32 110.2 2.4 2.2 1 1 1 2 2 2 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.28 EGC34271.1 - 5.4e-12 45.0 3.5 0.00041 20.1 0.0 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34271.1 - 1.7e-10 40.2 7.0 0.00083 19.4 0.0 6.0 7 0 0 7 7 5 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC34271.1 - 3.4e-09 36.1 3.2 0.091 12.9 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC34271.1 - 6.4e-07 29.7 0.1 14 6.8 0.0 5.9 4 2 2 6 6 6 0 Tetratricopeptide repeat Spt20 PF12090.8 EGC34271.1 - 4.9e-05 23.1 10.6 7.7e-05 22.4 10.6 1.4 1 0 0 1 1 1 1 Spt20 family ANAPC3 PF12895.7 EGC34271.1 - 0.00083 19.5 16.9 0.058 13.6 1.7 4.3 2 2 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 EPL1 PF10513.9 EGC34271.1 - 0.0015 18.9 2.7 0.0028 18.0 2.7 1.4 1 0 0 1 1 1 1 Enhancer of polycomb-like TPR_6 PF13174.6 EGC34271.1 - 0.0021 18.6 13.0 5.2 7.9 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat PIP5K PF01504.18 EGC34271.1 - 0.0087 15.3 1.3 0.017 14.3 1.3 1.4 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2722 PF10846.8 EGC34271.1 - 0.0088 15.0 13.7 0.013 14.4 13.7 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TPR_11 PF13414.6 EGC34271.1 - 0.015 14.9 8.3 0.017 14.8 0.0 3.9 4 1 1 5 5 4 0 TPR repeat TPR_9 PF13371.6 EGC34271.1 - 0.028 14.6 0.0 0.68 10.1 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF1151 PF06625.11 EGC34271.1 - 0.03 14.2 8.6 0.062 13.2 8.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) SpoIIP PF07454.11 EGC34271.1 - 0.074 12.5 6.7 0.16 11.4 6.7 1.5 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Fis1_TPR_C PF14853.6 EGC34271.1 - 0.09 12.9 4.4 0.25 11.4 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_12 PF13424.6 EGC34271.1 - 0.1 12.9 0.2 0.1 12.9 0.2 3.9 3 2 1 4 4 3 0 Tetratricopeptide repeat Presenilin PF01080.17 EGC34271.1 - 0.17 10.7 2.4 0.27 9.9 2.4 1.4 1 0 0 1 1 1 0 Presenilin TERB2 PF15101.6 EGC34271.1 - 0.88 9.6 9.6 1.6 8.7 9.6 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF4834 PF16118.5 EGC34271.1 - 1.1 10.3 7.2 2.1 9.3 7.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) ANAPC_CDC26 PF10471.9 EGC34271.1 - 4 8.3 20.2 9.7 7.1 20.2 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit CDC26 UDPGP PF01704.18 EGC34273.1 - 6.7e-187 621.2 4.9 7.8e-187 621.0 4.9 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase Phage_CI_C PF16452.5 EGC34273.1 - 0.034 14.4 0.0 0.23 11.8 0.0 2.3 2 1 0 2 2 2 0 Bacteriophage CI repressor C-terminal domain RRM_1 PF00076.22 EGC34274.1 - 2.7e-07 30.3 0.1 6.7e-07 29.0 0.1 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC34274.1 - 0.0013 18.7 1.3 0.0013 18.7 1.3 3.3 4 0 0 4 4 4 1 RNA binding motif VWA_2 PF13519.6 EGC34275.1 - 2.3e-13 50.7 0.0 2.3e-13 50.7 0.0 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain DUF2228 PF10228.9 EGC34275.1 - 0.028 14.2 4.4 0.083 12.6 4.4 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2228) DUF501 PF04417.12 EGC34275.1 - 0.81 9.5 4.3 1.9 8.3 3.6 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF501) DUF4638 PF15472.6 EGC34275.1 - 1.6 8.4 18.0 2.6 7.7 18.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) SLC12 PF03522.15 EGC34275.1 - 3.6 6.5 18.7 6.9 5.6 18.7 1.4 1 0 0 1 1 1 0 Solute carrier family 12 zf-TRAF PF02176.18 EGC34276.1 - 6e-12 46.1 20.2 1.2e-08 35.5 4.7 4.4 3 1 2 5 5 5 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC34276.1 - 0.0014 18.5 6.2 0.0014 18.5 6.2 3.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-U11-48K PF05253.12 EGC34276.1 - 0.3 11.1 8.4 22 5.1 0.1 4.2 3 1 0 3 3 3 0 U11-48K-like CHHC zinc finger Auto_anti-p27 PF06677.12 EGC34276.1 - 7.1 6.9 12.3 0.22 11.7 3.3 3.0 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) EF-hand_6 PF13405.6 EGC34277.1 - 1.9e-09 36.7 0.0 1.6e-05 24.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.32 EGC34277.1 - 3.6e-08 32.4 0.0 0.00041 19.7 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC34277.1 - 9.9e-08 31.7 0.0 0.013 15.3 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.6 EGC34277.1 - 3.4e-05 24.2 0.0 4.8e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGC34277.1 - 7.1e-05 22.1 0.0 0.46 10.1 0.0 2.1 2 0 0 2 2 2 2 EF hand CH PF00307.31 EGC34278.1 - 1.1e-80 266.9 0.3 5.8e-20 71.5 0.3 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.32 EGC34278.1 - 6.8e-15 53.4 5.4 3.4e-08 32.5 0.1 3.0 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGC34278.1 - 3.9e-13 49.6 0.3 1.3e-12 48.0 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC34278.1 - 4.5e-12 44.9 0.6 6.9e-06 25.6 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGC34278.1 - 6.2e-12 44.5 3.1 4.9e-05 22.6 0.3 3.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC34278.1 - 7.6e-11 41.7 1.6 6.7e-10 38.7 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.6 EGC34278.1 - 0.00023 21.4 0.1 0.00052 20.3 0.1 1.6 1 0 0 1 1 1 1 EF-hand domain CAMSAP_CH PF11971.8 EGC34278.1 - 0.00053 19.8 0.0 3.5 7.5 0.0 3.7 3 0 0 3 3 3 2 CAMSAP CH domain SPARC_Ca_bdg PF10591.9 EGC34278.1 - 0.042 14.2 0.1 0.11 12.9 0.1 1.7 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region CH_2 PF06294.11 EGC34278.1 - 0.13 12.4 0.0 3.4 7.8 0.0 3.1 4 0 0 4 4 4 0 CH-like domain in sperm protein Nbas_N PF15492.6 EGC34279.1 - 7.6e-11 41.9 0.1 7e-07 28.9 0.0 3.4 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal ANAPC4_WD40 PF12894.7 EGC34279.1 - 0.00041 20.6 0.0 0.48 10.7 0.0 4.0 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SWC7 PF17330.2 EGC34279.1 - 0.0027 17.7 0.2 0.0027 17.7 0.2 3.3 3 0 0 3 3 3 1 SWR1 chromatin-remodelling complex, sub-unit Swc7 WD40 PF00400.32 EGC34279.1 - 0.026 15.4 0.3 32 5.6 0.0 4.1 4 0 0 4 4 4 0 WD domain, G-beta repeat HAMP PF00672.25 EGC34280.1 - 1.1e-90 297.9 20.6 6.9e-07 29.5 0.0 13.6 13 0 0 13 13 13 12 HAMP domain Response_reg PF00072.24 EGC34280.1 - 8.9e-35 119.3 0.4 8.2e-28 96.8 0.3 3.1 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.26 EGC34280.1 - 8.5e-32 110.0 0.1 2.6e-31 108.4 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.25 EGC34280.1 - 2e-19 69.4 0.0 1.2e-18 66.9 0.0 2.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain DUF948 PF06103.11 EGC34280.1 - 3.1e-10 40.2 102.7 2.4 8.5 1.9 19.3 1 1 10 11 11 11 9 Bacterial protein of unknown function (DUF948) WXG100 PF06013.12 EGC34280.1 - 3.9e-10 39.8 39.0 1.2 9.4 0.2 13.7 12 2 2 15 15 15 4 Proteins of 100 residues with WXG SpoIIID PF12116.8 EGC34280.1 - 8.2e-10 38.6 4.6 6.1 7.0 0.0 10.4 12 0 0 12 12 12 1 Stage III sporulation protein D HTH_6 PF01418.17 EGC34280.1 - 6.2e-09 35.7 14.2 44 4.2 0.0 11.4 11 0 0 11 11 11 0 Helix-turn-helix domain, rpiR family GLE1 PF07817.13 EGC34280.1 - 9.4e-08 31.6 22.4 8.8 5.5 0.1 10.6 1 1 10 11 11 11 1 GLE1-like protein DUF1843 PF08898.10 EGC34280.1 - 4.7e-07 30.2 15.7 15 6.2 0.1 10.1 10 0 0 10 10 10 1 Domain of unknown function (DUF1843) DUF1759 PF03564.15 EGC34280.1 - 0.0035 17.3 24.4 61 3.5 0.0 11.1 12 0 0 12 12 12 0 Protein of unknown function (DUF1759) DUF3829 PF12889.7 EGC34280.1 - 0.068 12.6 54.9 5.6 6.3 0.1 11.0 9 3 1 11 11 10 0 Protein of unknown function (DUF3829) LINES_N PF14694.6 EGC34282.1 - 1.8e-18 67.1 2.9 5e-18 65.7 2.9 1.7 1 0 0 1 1 1 1 Lines N-terminus LINES_C PF14695.6 EGC34282.1 - 5.1e-05 22.6 0.9 0.00012 21.4 0.9 1.6 1 0 0 1 1 1 1 Lines C-terminus PRK PF00485.18 EGC34282.1 - 0.045 13.5 0.2 0.11 12.2 0.2 1.6 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UreE_N PF02814.15 EGC34283.1 - 0.2 11.3 0.0 0.4 10.3 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain GDPD PF03009.17 EGC34284.1 - 2.4e-57 194.6 4.6 3.6e-57 194.0 0.1 3.1 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_2 PF12796.7 EGC34284.1 - 8.2e-42 141.7 12.7 4.2e-10 40.1 0.1 4.9 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC34284.1 - 5.8e-31 106.5 4.0 5.1e-06 26.9 0.1 6.0 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC34284.1 - 1.9e-25 88.6 1.4 4.7e-09 36.3 0.2 6.7 3 2 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGC34284.1 - 4e-19 68.1 6.1 0.0011 19.3 0.1 7.5 8 0 0 8 8 8 4 Ankyrin repeat Ank_3 PF13606.6 EGC34284.1 - 2.3e-17 61.3 6.6 0.14 12.8 0.0 9.0 9 0 0 9 9 9 5 Ankyrin repeat CBM_20 PF00686.19 EGC34284.1 - 1.6e-16 60.0 0.5 5e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Starch binding domain Band_7 PF01145.25 EGC34285.1 - 1.8e-25 90.0 0.1 2.5e-25 89.5 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.8 EGC34285.1 - 0.0006 19.0 0.4 0.00076 18.6 0.4 1.1 1 0 0 1 1 1 1 SigmaW regulon antibacterial Med2 PF11214.8 EGC34285.1 - 0.0023 18.1 1.6 0.0038 17.3 1.6 1.4 1 0 0 1 1 1 1 Mediator complex subunit 2 BPL_N PF09825.9 EGC34285.1 - 0.046 12.8 0.3 0.055 12.6 0.3 1.1 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal CBM49 PF09478.10 EGC34286.1 - 3.9e-16 59.1 0.2 5.4e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Hexapep PF00132.24 EGC34287.1 - 2.3e-15 55.6 10.9 5.1e-07 29.2 0.3 4.1 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.6 EGC34287.1 - 3.4e-10 39.5 9.7 1.6e-05 24.5 1.9 3.4 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.12 EGC34287.1 - 0.0094 14.9 0.1 0.076 11.9 0.0 2.0 1 1 1 2 2 2 1 L-fucokinase Cpn10 PF00166.21 EGC34288.1 - 0.00025 21.0 0.0 0.00028 20.9 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit AHSP PF09236.10 EGC34288.1 - 0.084 13.3 0.0 0.14 12.6 0.0 1.3 2 0 0 2 2 2 0 Alpha-haemoglobin stabilising protein PGK PF00162.19 EGC34289.1 - 9.8e-152 505.3 1.4 1.1e-151 505.1 1.4 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DUF3172 PF11371.8 EGC34289.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3172) Mlh1_C PF16413.5 EGC34291.1 - 1.2e-84 283.9 1.1 1.2e-84 283.9 1.1 2.3 2 1 0 2 2 2 1 DNA mismatch repair protein Mlh1 C-terminus DNA_mis_repair PF01119.19 EGC34291.1 - 1.3e-30 105.5 0.4 3.8e-30 104.0 0.4 1.9 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGC34291.1 - 3.3e-11 43.2 2.8 1e-10 41.6 0.1 2.8 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGC34291.1 - 1.5e-06 28.7 1.2 4.5e-06 27.2 0.0 2.4 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase SUIM_assoc PF16619.5 EGC34291.1 - 1.6 8.8 14.4 0.033 14.2 2.9 3.0 3 0 0 3 3 3 0 Unstructured region C-term to UIM in Ataxin3 FNIP PF05725.12 EGC34292.1 - 2.6e-33 113.9 25.6 5e-10 39.4 1.3 6.6 3 2 3 7 7 7 7 FNIP Repeat LRR_1 PF00560.33 EGC34292.1 - 0.011 16.2 6.6 0.43 11.3 0.2 5.1 4 1 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.6 EGC34292.1 - 0.25 11.5 9.1 0.56 10.4 0.0 4.4 5 0 0 5 5 5 0 Leucine Rich repeat EGF_2 PF07974.13 EGC34293.1 - 0.046 14.1 10.9 0.11 12.9 10.9 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 EGC34294.1 - 0.00094 19.5 30.6 0.0016 18.7 11.8 3.0 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.7 EGC34294.1 - 0.11 13.2 15.4 0.1 13.3 4.2 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF Laminin_EGF PF00053.24 EGC34294.1 - 5.4 7.2 26.6 2.8 8.2 8.3 3.1 3 0 0 3 3 3 0 Laminin EGF domain LRR_1 PF00560.33 EGC34294.1 - 9.8 7.2 9.1 34 5.6 0.2 5.9 3 1 0 3 3 3 0 Leucine Rich Repeat Brix PF04427.18 EGC34295.1 - 3.9e-37 128.2 0.3 5.5e-37 127.8 0.3 1.2 1 0 0 1 1 1 1 Brix domain DUF3484 PF11983.8 EGC34295.1 - 1.9 9.7 7.1 4.8 8.4 7.1 1.7 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch LSM PF01423.22 EGC34296.1 - 1.3e-15 56.8 0.7 1.4e-15 56.7 0.7 1.0 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGC34296.1 - 0.06 13.0 0.2 0.12 12.0 0.1 1.6 2 0 0 2 2 2 0 Hfq protein BAR_3 PF16746.5 EGC34297.1 - 1.8e-07 31.1 9.2 2.4e-07 30.7 9.2 1.1 1 0 0 1 1 1 1 BAR domain of APPL family Tape_meas_lam_C PF09718.10 EGC34297.1 - 0.014 15.5 0.1 0.097 12.8 0.0 2.4 3 0 0 3 3 3 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) ssDBP_DBD PF18361.1 EGC34297.1 - 0.018 15.1 2.1 1.2 9.2 0.3 2.4 1 1 1 2 2 2 0 Single stranded DNA-binding protein ss DNA binding domain DUF4047 PF13256.6 EGC34297.1 - 0.058 13.6 0.7 0.058 13.6 0.7 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4047) Ceramidase PF05875.12 EGC34298.1 - 9.4e-60 202.3 15.2 1.2e-59 201.9 15.2 1.1 1 0 0 1 1 1 1 Ceramidase TcpE PF12648.7 EGC34298.1 - 0.011 16.3 10.7 0.04 14.5 0.5 2.8 2 1 0 2 2 2 0 TcpE family Glycos_transf_2 PF00535.26 EGC34299.1 - 2.9e-27 95.5 0.0 3.9e-27 95.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EGC34299.1 - 2.6e-06 27.1 0.0 3.8e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EGC34299.1 - 1.4e-05 25.1 0.0 2.1e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGC34299.1 - 0.0052 17.3 0.0 0.01 16.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 DNA_methylase PF00145.17 EGC34300.1 - 2.5e-42 145.4 6.2 2.9e-42 145.2 6.2 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF2951 PF11166.8 EGC34300.1 - 0.29 11.4 7.2 0.099 12.9 3.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2951) zf-rbx1 PF12678.7 EGC34301.1 - 2.5e-25 88.5 13.3 3.3e-25 88.1 13.3 1.2 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGC34301.1 - 2.6e-17 62.7 10.1 3.3e-17 62.3 10.1 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.6 EGC34301.1 - 1.8e-06 28.1 14.8 7.6e-05 23.0 14.8 2.3 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC34301.1 - 4.4e-05 23.2 3.3 4.4e-05 23.2 3.3 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC34301.1 - 0.00089 19.1 12.4 0.021 14.7 12.4 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGC34301.1 - 0.14 12.3 8.9 1.6 8.9 9.3 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EGC34301.1 - 0.21 11.3 15.6 20 5.0 15.6 2.4 1 1 0 1 1 1 0 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGC34301.1 - 0.3 11.0 11.7 0.9 9.5 5.3 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC34301.1 - 0.53 10.4 8.1 2.2 8.4 8.1 2.1 1 1 0 1 1 1 0 RING-type zinc-finger Zn_ribbon_17 PF17120.5 EGC34301.1 - 0.91 9.2 15.0 0.28 10.8 5.1 2.3 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGC34301.1 - 6.4 6.8 12.9 61 3.7 12.9 2.5 1 1 1 2 2 2 0 zinc-RING finger domain Crystall_3 PF08964.10 EGC34302.1 - 0.028 14.6 1.7 0.056 13.6 1.7 1.5 1 1 0 1 1 1 0 Beta/Gamma crystallin SLT PF01464.20 EGC34303.1 - 3.1e-14 52.6 0.0 4.1e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGC34303.1 - 0.0015 18.8 1.4 0.0087 16.3 1.4 1.9 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Tim17 PF02466.19 EGC34304.1 - 3.8e-26 91.6 3.9 3.8e-26 91.6 3.9 1.9 1 1 1 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family DUF533 PF04391.12 EGC34304.1 - 0.0082 15.7 1.7 0.0082 15.7 1.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF533) DUF4199 PF13858.6 EGC34304.1 - 0.02 15.3 0.3 0.033 14.6 0.3 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) G0-G1_switch_2 PF15103.6 EGC34304.1 - 0.066 13.7 5.4 0.12 12.8 5.4 1.4 1 0 0 1 1 1 0 G0/G1 switch protein 2 CstA PF02554.14 EGC34304.1 - 0.088 11.7 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Carbon starvation protein CstA ATP-synt_E PF05680.12 EGC34304.1 - 0.29 11.5 9.8 0.51 10.7 9.8 1.4 1 0 0 1 1 1 0 ATP synthase E chain Presenilin PF01080.17 EGC34304.1 - 0.33 9.7 1.6 0.37 9.5 1.6 1.1 1 0 0 1 1 1 0 Presenilin HD_4 PF13328.6 EGC34304.1 - 0.34 10.6 3.4 0.67 9.7 3.4 1.6 1 1 0 1 1 1 0 HD domain Peptidase_S49_N PF08496.10 EGC34304.1 - 0.45 10.6 7.5 0.58 10.2 7.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.6 EGC34304.1 - 7.3 5.5 9.9 9.3 5.1 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Ribonucleas_3_3 PF14622.6 EGC34305.1 - 2.9e-35 121.2 0.0 1.8e-18 66.9 0.0 2.7 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.26 EGC34305.1 - 3e-34 117.8 7.7 2e-18 67.0 0.0 4.2 4 3 0 4 4 3 2 Ribonuclease III domain dsrm PF00035.26 EGC34305.1 - 4.8e-15 56.0 0.1 1.3e-14 54.7 0.1 1.8 1 0 0 1 1 1 1 Double-stranded RNA binding motif DUF948 PF06103.11 EGC34305.1 - 0.073 13.3 1.1 0.23 11.7 1.1 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) YgaB PF14182.6 EGC34305.1 - 0.28 11.6 12.3 0.043 14.2 6.4 2.7 3 0 0 3 3 2 0 YgaB-like protein SesA PF17107.5 EGC34305.1 - 0.71 10.1 4.0 0.4 10.9 1.2 2.0 2 0 0 2 2 2 0 N-terminal domain on NACHT_NTPase and P-loop NTPases TSC22 PF01166.18 EGC34305.1 - 0.86 10.0 4.1 25 5.3 0.5 3.1 1 1 1 2 2 2 0 TSC-22/dip/bun family Tup_N PF08581.10 EGC34305.1 - 1.2 9.5 11.7 0.15 12.4 6.7 2.1 2 0 0 2 2 1 0 Tup N-terminal DUF1664 PF07889.12 EGC34305.1 - 1.4 9.0 10.0 0.15 12.1 4.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) FmiP_Thoc5 PF09766.9 EGC34305.1 - 2.5 7.3 25.7 8.7 5.5 25.7 1.8 1 1 0 1 1 1 0 Fms-interacting protein/Thoc5 CLZ PF16526.5 EGC34305.1 - 5 7.6 11.5 17 5.9 5.7 3.0 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels SR-25 PF10500.9 EGC34305.1 - 6.6 6.3 17.4 0.13 11.9 2.2 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Claudin_3 PF06653.11 EGC34306.1 - 0.0013 18.7 13.2 0.0027 17.7 12.2 1.8 1 1 1 2 2 2 2 Tight junction protein, Claudin-like Corona_M PF01635.18 EGC34306.1 - 2.4 7.4 13.4 9.5e+02 -1.1 13.4 2.2 1 1 0 1 1 1 0 Coronavirus M matrix/glycoprotein DHHC PF01529.20 EGC34306.1 - 3.2 7.9 16.4 1 9.5 8.1 2.1 1 1 1 2 2 2 0 DHHC palmitoyltransferase 2OG-FeII_Oxy_3 PF13640.6 EGC34307.1 - 2.7e-13 50.6 0.9 3.6e-13 50.2 0.3 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.13 EGC34307.1 - 0.00082 19.7 0.0 0.88 9.8 0.0 2.2 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.6 EGC34307.1 - 0.12 12.8 0.5 0.33 11.4 0.1 2.0 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase Ran_BP1 PF00638.18 EGC34308.1 - 1.3e-42 144.9 0.2 5.4e-42 142.9 0.0 1.8 1 1 1 2 2 2 1 RanBP1 domain WH1 PF00568.23 EGC34308.1 - 0.00038 20.4 0.2 0.004 17.1 0.2 2.2 1 1 0 1 1 1 1 WH1 domain AMIN PF11741.8 EGC34308.1 - 0.1 12.8 0.2 0.2 11.8 0.2 1.6 1 1 0 1 1 1 0 AMIN domain Rif1_N PF12231.8 EGC34309.1 - 3e-40 138.4 20.1 3e-40 138.4 20.1 3.0 4 0 0 4 4 4 1 Rap1-interacting factor 1 N terminal DNA_pol_A_exo1 PF01612.20 EGC34311.1 - 6.1e-46 156.3 0.4 1.3e-45 155.2 0.4 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.12 EGC34311.1 - 2.3e-19 69.9 0.1 2.3e-19 69.9 0.1 4.4 3 1 1 4 4 4 1 PMC2NT (NUC016) domain HRDC PF00570.23 EGC34311.1 - 3e-12 46.3 0.0 7.8e-12 45.0 0.0 1.7 1 0 0 1 1 1 1 HRDC domain Tweety PF04906.13 EGC34311.1 - 8.1 5.0 8.3 3.5 6.2 5.2 1.9 1 1 0 1 1 1 0 Tweety ketoacyl-synt PF00109.26 EGC34312.1 - 4.5e-63 213.2 0.0 7.9e-63 212.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34312.1 - 6.5e-43 147.4 0.0 1.6e-42 146.2 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34312.1 - 2.8e-33 114.4 0.0 1.4e-32 112.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34312.1 - 5.8e-24 85.0 0.0 1.4e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC34312.1 - 7e-22 78.0 3.2 2.2e-21 76.4 0.0 3.5 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC34312.1 - 2.3e-18 66.7 0.2 8.4e-18 64.9 0.2 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC34312.1 - 1.1e-15 57.7 0.0 1.6e-15 57.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC34312.1 - 2.3e-10 41.7 0.0 5.9e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC34312.1 - 1.8e-06 27.8 0.0 4.5e-06 26.5 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC34312.1 - 4.6e-06 26.9 0.3 1.2e-05 25.5 0.3 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_25 PF13649.6 EGC34312.1 - 8.3e-06 26.4 0.0 3.3e-05 24.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34312.1 - 2.8e-05 24.7 0.0 0.0001 22.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC34312.1 - 3.2e-05 23.4 0.0 6.8e-05 22.4 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC34312.1 - 3.6e-05 23.7 0.0 0.00011 22.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC34312.1 - 0.025 13.9 0.0 0.065 12.6 0.0 1.6 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family DUF1430 PF07242.11 EGC34312.1 - 0.026 14.8 0.3 0.14 12.4 0.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) Methyltransf_28 PF02636.17 EGC34312.1 - 0.032 13.9 0.6 1.2 8.7 0.0 3.1 3 0 0 3 3 3 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGC34312.1 - 0.15 11.9 1.8 2.4 7.9 0.0 3.8 3 0 0 3 3 2 0 Methyltransferase domain ketoacyl-synt PF00109.26 EGC34313.1 - 7.1e-63 212.5 0.0 1.4e-62 211.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34313.1 - 1.1e-41 143.4 0.0 1.8e-41 142.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34313.1 - 3.5e-33 114.1 0.0 2.7e-32 111.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34313.1 - 3.2e-24 85.8 0.0 8.1e-24 84.5 0.0 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC34313.1 - 5e-23 81.7 4.0 8.9e-22 77.7 0.0 4.5 4 0 0 4 4 3 1 Methyltransferase domain PS-DH PF14765.6 EGC34313.1 - 9.4e-16 57.9 0.0 1.4e-15 57.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC34313.1 - 2.5e-15 56.9 0.1 7.7e-15 55.3 0.1 2.0 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC34313.1 - 5.2e-10 40.5 0.0 1.9e-09 38.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EGC34313.1 - 1.1e-06 29.3 0.0 6.3e-06 26.8 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34313.1 - 3.6e-06 27.5 0.0 3e-05 24.6 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EGC34313.1 - 2.7e-05 24.0 0.0 6.8e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC34313.1 - 3e-05 24.3 0.1 7.7e-05 23.0 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EGC34313.1 - 5.4e-05 23.1 0.0 0.00019 21.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC34313.1 - 7.4e-05 22.2 0.0 0.00014 21.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Ubie_methyltran PF01209.18 EGC34313.1 - 0.0061 15.9 0.0 0.015 14.6 0.0 1.6 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_28 PF02636.17 EGC34313.1 - 0.007 16.0 0.0 0.67 9.5 0.0 2.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGC34313.1 - 0.084 12.7 4.3 3.1 7.6 0.0 4.4 4 0 0 4 4 4 0 Methyltransferase domain ketoacyl-synt PF00109.26 EGC34314.1 - 5.8e-64 216.1 0.0 8.9e-64 215.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34314.1 - 5e-42 144.5 0.0 8.4e-42 143.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34314.1 - 8.7e-32 109.6 0.0 7.1e-31 106.7 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34314.1 - 2.9e-24 86.0 0.1 6.9e-24 84.7 0.1 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC34314.1 - 4.9e-21 75.3 4.4 5.3e-21 75.2 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain PS-DH PF14765.6 EGC34314.1 - 7.6e-21 74.6 0.0 1.2e-20 74.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC34314.1 - 1e-08 36.3 0.0 9e-08 33.2 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase KAsynt_C_assoc PF16197.5 EGC34314.1 - 4e-08 33.7 0.2 1.5e-07 31.9 0.2 2.1 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Thiolase_N PF00108.23 EGC34314.1 - 1e-05 25.0 0.0 2.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 EGC34314.1 - 3.7e-05 23.6 0.1 9.7e-05 22.2 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC34314.1 - 4e-05 23.5 0.0 0.00017 21.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34314.1 - 0.00016 22.3 0.0 0.00055 20.5 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC34314.1 - 0.0005 20.4 0.2 0.0012 19.1 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGC34314.1 - 0.016 15.0 4.0 0.045 13.5 0.0 3.7 3 0 0 3 3 3 0 Methyltransferase domain DUF1430 PF07242.11 EGC34314.1 - 0.028 14.7 1.9 0.078 13.3 0.5 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) Pentapeptide_4 PF13599.6 EGC34317.1 - 2e-09 37.5 32.3 2.1e-06 27.8 13.8 3.8 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGC34317.1 - 3.7e-06 27.0 21.2 0.00025 21.1 4.2 3.9 2 1 1 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.22 EGC34317.1 - 0.00023 20.7 22.3 0.00055 19.5 4.6 4.0 4 1 1 5 5 5 3 Pentapeptide repeats (8 copies) zf-RING_2 PF13639.6 EGC34317.1 - 0.00093 19.5 9.3 0.00093 19.5 9.3 2.6 2 0 0 2 2 2 1 Ring finger domain zf-TRAF PF02176.18 EGC34317.1 - 0.0065 17.1 0.5 0.042 14.5 0.5 2.4 1 0 0 1 1 1 1 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC34317.1 - 0.0099 15.7 8.8 0.0099 15.7 8.8 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC34317.1 - 0.13 12.5 10.0 0.28 11.3 5.6 2.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-C3HC4_2 PF13923.6 EGC34317.1 - 0.41 10.5 13.6 0.11 12.4 9.1 2.4 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Exonuc_VII_L PF02601.15 EGC34317.1 - 0.66 9.5 22.8 1.1 8.8 22.8 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit zf-RING_UBOX PF13445.6 EGC34317.1 - 0.77 9.8 12.7 0.11 12.6 3.5 3.5 2 1 1 3 3 3 0 RING-type zinc-finger PAT1 PF09770.9 EGC34317.1 - 2 6.6 40.5 3.2 5.9 40.5 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1501 PF07394.12 EGC34317.1 - 5.2 6.0 22.8 9.2 5.2 22.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) ALMT PF11744.8 EGC34318.1 - 6.7e-35 120.8 6.6 6.7e-35 120.8 6.6 3.7 4 0 0 4 4 4 2 Aluminium activated malate transporter FUSC_2 PF13515.6 EGC34318.1 - 9.5e-13 48.4 19.3 3.9e-11 43.2 6.5 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.12 EGC34318.1 - 0.00036 19.2 5.0 0.0012 17.5 5.0 1.8 1 0 0 1 1 1 1 Fusaric acid resistance protein family Rick_17kDa_Anti PF05433.15 EGC34318.1 - 0.44 10.5 0.9 0.69 9.8 0.1 1.6 2 0 0 2 2 2 0 Glycine zipper 2TM domain Ni_hydr_CYTB PF01292.20 EGC34318.1 - 7.1 6.2 11.0 0.12 12.0 1.9 2.5 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 PAP_assoc PF03828.19 EGC34319.1 - 2.7e-06 27.5 0.2 2.7e-06 27.5 0.2 2.8 2 1 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.23 EGC34319.1 - 4.3e-05 23.7 0.4 0.00015 22.0 0.0 2.1 2 0 0 2 2 2 1 Nucleotidyltransferase domain Copper-fist PF00649.18 EGC34319.1 - 0.035 13.6 0.1 0.11 12.1 0.1 1.8 1 0 0 1 1 1 0 Copper fist DNA binding domain CPSase_L_D3 PF02787.19 EGC34319.1 - 0.88 9.9 5.7 0.44 10.9 1.3 2.5 1 1 1 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Carboxyl_trans PF01039.22 EGC34320.1 - 6.4e-157 523.1 0.1 7.5e-157 522.9 0.1 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain ACCA PF03255.14 EGC34320.1 - 0.0045 16.9 0.0 0.29 11.0 0.0 2.5 2 0 0 2 2 2 1 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit MdcE PF06833.11 EGC34320.1 - 0.036 13.6 0.1 0.34 10.4 0.0 2.2 2 0 0 2 2 2 0 Malonate decarboxylase gamma subunit (MdcE) ECH_1 PF00378.20 EGC34320.1 - 0.29 10.4 1.1 1.9 7.8 0.0 2.3 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase ketoacyl-synt PF00109.26 EGC34321.1 - 1.5e-63 214.7 0.0 2.9e-63 213.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34321.1 - 6.8e-44 150.7 0.0 1.2e-43 149.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34321.1 - 2.2e-33 114.8 0.0 2.9e-32 111.1 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KAsynt_C_assoc PF16197.5 EGC34321.1 - 1.3e-16 61.0 0.0 3.7e-16 59.6 0.0 1.8 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC34321.1 - 2e-12 47.0 0.0 2.9e-12 46.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.23 EGC34321.1 - 1.1e-06 28.2 0.1 2.7e-06 27.0 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glycos_transf_1 PF00534.20 EGC34322.1 - 2.5e-38 131.3 0.0 5.9e-38 130.1 0.0 1.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC34322.1 - 3.1e-14 53.5 0.0 4.5e-14 53.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC34322.1 - 2.5e-09 37.4 0.0 3.7e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGC34322.1 - 0.0097 16.4 0.0 0.014 15.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.6 EGC34322.1 - 0.041 14.3 0.0 0.096 13.1 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferases group 1 7TM_GPCR_Str PF10326.9 EGC34323.1 - 0.011 15.1 1.9 0.014 14.8 0.9 1.6 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Str RSN1_TM PF13967.6 EGC34323.1 - 0.02 14.7 1.3 6.8 6.4 1.5 2.5 2 1 0 2 2 2 0 Late exocytosis, associated with Golgi transport DUF1199 PF06712.11 EGC34323.1 - 0.061 13.4 0.0 17 5.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) DUF4834 PF16118.5 EGC34323.1 - 0.19 12.7 0.0 0.19 12.7 0.0 4.5 2 1 2 4 4 4 0 Domain of unknown function (DUF4834) CSG2 PF16965.5 EGC34323.1 - 0.64 8.9 7.7 0.53 9.2 0.3 2.3 2 1 0 2 2 2 0 Ceramide synthase regulator Connexin PF00029.19 EGC34323.1 - 5 6.8 8.5 1.2 8.8 0.0 2.7 2 1 1 3 3 3 0 Connexin OATP PF03137.20 EGC34323.1 - 5.6 5.1 9.3 0.032 12.5 0.6 1.6 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DDHD PF02862.17 EGC34324.1 - 2.5e-35 122.7 10.0 2.5e-35 122.7 10.0 4.2 2 2 1 3 3 3 1 DDHD domain Abhydrolase_8 PF06259.12 EGC34324.1 - 0.053 13.2 0.6 0.098 12.3 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase Ribosomal_L32e PF01655.18 EGC34325.1 - 1.2e-45 154.4 0.1 1.8e-45 153.8 0.1 1.3 1 0 0 1 1 1 1 Ribosomal protein L32 RNA_pol_N PF01194.17 EGC34325.1 - 9.6e-31 105.9 1.8 1.7e-30 105.1 1.8 1.4 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Lectin_leg-like PF03388.13 EGC34326.1 - 6.9e-64 215.3 0.3 6.9e-64 215.3 0.3 2.0 2 0 0 2 2 2 1 Legume-like lectin family Bact_lectin PF18483.1 EGC34326.1 - 1.8e-11 44.4 1.3 1.8e-11 44.4 1.3 2.8 2 1 1 3 3 3 1 Bacterial lectin Caldesmon PF02029.15 EGC34326.1 - 0.79 8.4 40.2 1.1 8.0 40.2 1.1 1 0 0 1 1 1 0 Caldesmon SID-1_RNA_chan PF13965.6 EGC34326.1 - 1.4 7.2 13.4 3.1 6.1 13.4 1.6 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 AA_permease_2 PF13520.6 EGC34327.1 - 3.2e-48 164.6 47.7 4.1e-48 164.3 47.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC34327.1 - 0.0014 17.4 40.9 0.032 12.8 40.3 2.5 1 1 0 1 1 1 1 Amino acid permease zf-SNAP50_C PF12251.8 EGC34328.1 - 5.2e-66 222.2 9.2 6.4e-66 221.8 9.2 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal PAP_fibrillin PF04755.12 EGC34330.1 - 0.1 12.5 1.2 0.15 12.0 1.2 1.3 1 0 0 1 1 1 0 PAP_fibrillin DDE_Tnp_ISL3 PF01610.17 EGC34330.1 - 0.2 11.4 0.7 6 6.5 0.3 2.1 2 0 0 2 2 2 0 Transposase PriX PF18689.1 EGC34331.1 - 0.038 14.3 3.3 0.2 12.0 1.1 2.4 2 0 0 2 2 2 0 Primase X RIG-I_C-RD PF11648.8 EGC34331.1 - 0.071 13.3 0.9 0.11 12.7 0.9 1.2 1 0 0 1 1 1 0 C-terminal domain of RIG-I TFIID_20kDa PF03847.13 EGC34332.1 - 7.7e-32 109.6 0.6 9.3e-32 109.4 0.6 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A CBFD_NFYB_HMF PF00808.23 EGC34332.1 - 0.0035 17.6 0.1 0.0048 17.1 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC34332.1 - 0.015 15.6 0.1 0.021 15.2 0.1 1.2 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 FCH PF00611.23 EGC34333.1 - 4.7e-15 55.6 0.1 4.7e-15 55.6 0.1 2.6 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.6 EGC34333.1 - 4.6e-12 45.6 0.1 9.1e-12 44.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC34333.1 - 3.8e-11 42.4 0.1 7e-11 41.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGC34333.1 - 4e-05 23.2 0.0 8.7e-05 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TPR_MLP1_2 PF07926.12 EGC34333.1 - 0.00077 19.5 12.3 0.018 15.1 1.8 3.3 1 1 3 4 4 4 2 TPR/MLP1/MLP2-like protein TEX12 PF15219.6 EGC34333.1 - 0.0046 17.2 2.8 1.4 9.3 0.3 2.6 1 1 1 2 2 2 2 Testis-expressed 12 Seryl_tRNA_N PF02403.22 EGC34333.1 - 0.04 14.2 12.9 0.25 11.6 0.4 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DASH_Dad1 PF08649.10 EGC34333.1 - 0.054 13.7 0.7 1.2 9.4 0.0 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 SHE3 PF17078.5 EGC34333.1 - 0.057 13.1 19.4 0.033 13.9 14.6 2.2 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 SOGA PF11365.8 EGC34333.1 - 0.75 11.0 9.4 0.22 12.7 4.7 2.5 1 1 1 2 2 2 0 Protein SOGA DUF4407 PF14362.6 EGC34333.1 - 1.9 7.8 4.7 2.9 7.1 4.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) OmpH PF03938.14 EGC34333.1 - 8.6 6.7 20.0 7.9 6.8 17.2 2.3 2 1 1 3 3 3 0 Outer membrane protein (OmpH-like) OTU PF02338.19 EGC34334.1 - 1.7e-11 44.7 0.0 1.7e-11 44.7 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Mitofilin PF09731.9 EGC34334.1 - 0.0037 16.2 18.4 0.005 15.7 18.4 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein CDC27 PF09507.10 EGC34334.1 - 3.7 6.8 34.1 5.9 6.2 34.1 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 PAT1 PF09770.9 EGC34334.1 - 7.1 4.8 40.9 9.9 4.3 40.9 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MOZART2 PF12926.7 EGC34335.1 - 1.3 8.7 4.2 2.8 7.6 4.2 1.6 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated PAP1 PF08601.10 EGC34335.1 - 4.2 7.0 16.2 5.6 6.6 16.2 1.1 1 0 0 1 1 1 0 Transcription factor PAP1 DUF1748 PF08520.10 EGC34336.1 - 1.2e-08 34.7 0.0 1.9e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Presenilin PF01080.17 EGC34336.1 - 1.5 7.5 5.9 1.7 7.3 5.9 1.1 1 0 0 1 1 1 0 Presenilin UCH PF00443.29 EGC34337.1 - 3.4e-54 184.0 1.5 3.4e-54 184.0 1.5 3.0 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC34337.1 - 8e-23 81.5 1.7 8e-23 81.5 1.7 2.9 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase TFIIA PF03153.13 EGC34337.1 - 7.2 6.5 51.9 6.9 6.5 18.2 2.4 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit DIM PF08194.12 EGC34338.1 - 0.25 11.6 0.7 2.1 8.6 0.0 2.4 2 0 0 2 2 2 0 DIM protein SIS PF01380.22 EGC34339.1 - 7e-17 61.5 2.7 2.4e-10 40.4 0.5 2.3 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.6 EGC34339.1 - 2.9e-05 24.1 0.1 0.21 11.6 0.0 2.7 2 1 1 3 3 3 2 SIS domain Pkinase PF00069.25 EGC34340.1 - 1.5e-72 244.2 1.4 1.5e-72 244.2 1.4 2.6 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34340.1 - 1.5e-37 129.3 0.1 4.2e-37 127.8 0.1 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.18 EGC34340.1 - 7.5e-20 70.9 0.4 2.7e-13 49.9 0.1 5.2 5 0 0 5 5 5 2 POLO box duplicated region Plectin PF00681.20 EGC34340.1 - 0.053 13.4 0.0 0.14 12.1 0.0 1.7 1 0 0 1 1 1 0 Plectin repeat WD40 PF00400.32 EGC34341.1 - 3.3e-17 62.5 2.0 0.0024 18.6 0.0 5.5 5 1 1 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34341.1 - 5.6e-06 26.6 0.7 0.39 11.1 0.1 3.8 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC34341.1 - 0.00019 20.2 1.6 0.4 9.3 0.0 3.1 2 1 1 3 3 3 3 Nucleoporin Nup120/160 eIF2A PF08662.11 EGC34341.1 - 0.0018 18.2 1.7 0.13 12.1 0.4 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Methyltransf_23 PF13489.6 EGC34342.1 - 2.1e-21 76.5 0.0 3e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Elf1 PF05129.13 EGC34342.1 - 0.02 14.9 4.0 0.03 14.4 3.0 1.8 2 0 0 2 2 2 0 Transcription elongation factor Elf1 like zf-Mss51 PF13824.6 EGC34342.1 - 0.027 14.6 1.6 0.027 14.6 1.6 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 Acetyltransf_1 PF00583.25 EGC34343.1 - 2.8e-11 43.7 0.0 0.011 16.0 0.0 4.5 4 0 0 4 4 4 3 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC34343.1 - 4.1e-08 33.5 0.5 0.025 15.0 0.0 4.1 4 0 0 4 4 4 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC34343.1 - 1.5e-07 31.4 0.0 0.26 11.4 0.0 4.4 4 0 0 4 4 4 3 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGC34343.1 - 4.5e-05 23.3 0.4 4.9 7.2 0.0 4.5 4 0 0 4 4 4 2 FR47-like protein Acetyltransf_10 PF13673.7 EGC34343.1 - 5.4e-05 23.1 0.2 1.3 8.9 0.0 4.4 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain HTH_50 PF18024.1 EGC34343.1 - 1.3 8.7 3.4 38 4.0 0.1 3.3 3 0 0 3 3 3 0 Helix-turn-helix domain Alpha_L_fucos PF01120.17 EGC34344.1 - 2.7e-116 388.9 10.0 3.4e-116 388.5 10.0 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase Fucosidase_C PF16757.5 EGC34344.1 - 1.1e-13 51.6 0.0 2.1e-13 50.7 0.0 1.5 1 0 0 1 1 1 1 Alpha-L-fucosidase C-terminal domain CDCA PF18484.1 EGC34344.1 - 0.098 12.5 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 Cadmium carbonic anhydrase repeat AhpC-TSA PF00578.21 EGC34345.1 - 2.3e-37 127.7 0.0 3.4e-37 127.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC34345.1 - 1.2e-16 60.8 0.0 1.5e-16 60.5 0.0 1.2 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.9 EGC34345.1 - 4.9e-10 39.1 0.0 1e-09 38.1 0.0 1.6 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin SCO1-SenC PF02630.14 EGC34345.1 - 0.0091 15.9 0.0 0.064 13.2 0.0 2.0 2 0 0 2 2 2 1 SCO1/SenC DUF2633 PF11119.8 EGC34346.1 - 0.029 14.3 0.5 0.029 14.3 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) DUF423 PF04241.15 EGC34346.1 - 0.029 14.5 0.1 0.059 13.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF423) TMEM154 PF15102.6 EGC34346.1 - 0.062 13.2 0.9 0.062 13.2 0.9 1.7 2 0 0 2 2 2 0 TMEM154 protein family DUF2207 PF09972.9 EGC34346.1 - 0.092 11.5 3.5 0.08 11.7 2.6 1.3 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Erf4 PF10256.9 EGC34346.1 - 0.11 12.6 0.4 0.2 11.8 0.4 1.6 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family ABC2_membrane PF01061.24 EGC34346.1 - 0.16 11.4 6.9 0.23 10.8 6.9 1.2 1 0 0 1 1 1 0 ABC-2 type transporter WAP PF00095.21 EGC34347.1 - 0.00059 20.2 5.7 0.0008 19.8 5.7 1.2 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' VKG_Carbox PF05090.14 EGC34347.1 - 0.081 11.8 0.0 0.086 11.7 0.0 1.0 1 0 0 1 1 1 0 Vitamin K-dependent gamma-carboxylase ATP-synt_8 PF00895.20 EGC34347.1 - 0.11 13.0 2.1 0.16 12.5 2.1 1.4 1 0 0 1 1 1 0 ATP synthase protein 8 tRNA-synt_2b PF00587.25 EGC34348.1 - 3.4e-33 115.1 0.0 6.7e-33 114.2 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGC34348.1 - 6.8e-15 55.0 0.5 1.4e-14 54.0 0.5 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.21 EGC34348.1 - 0.0034 17.4 0.0 0.0066 16.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain DUF4423 PF14394.6 EGC34348.1 - 0.022 14.5 0.3 0.052 13.3 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4423) DHHC PF01529.20 EGC34349.1 - 5.9e-37 126.8 9.5 5.9e-37 126.8 9.5 2.2 2 0 0 2 2 2 1 DHHC palmitoyltransferase WD40 PF00400.32 EGC34350.1 - 5.3e-18 65.0 8.2 5.4e-05 23.9 0.0 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat Peptidase_M15_4 PF13539.6 EGC34350.1 - 0.028 14.9 1.6 0.063 13.8 0.3 2.3 3 0 0 3 3 3 0 D-alanyl-D-alanine carboxypeptidase MID_MedPIWI PF18296.1 EGC34350.1 - 0.95 9.2 7.5 1.7 8.4 7.5 1.4 1 0 0 1 1 1 0 MID domain of medPIWI ABC2_membrane PF01061.24 EGC34351.1 - 1.1e-84 283.1 58.3 1.3e-47 162.0 21.1 2.6 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC34351.1 - 1.6e-38 132.3 0.0 9.1e-19 68.3 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.12 EGC34351.1 - 1.3e-23 82.7 4.0 7.1e-18 64.3 0.4 4.4 3 1 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC34351.1 - 9.5e-12 45.4 0.1 2.5e-11 44.0 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGC34351.1 - 5.8e-07 29.6 0.1 4.1e-05 23.5 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC34351.1 - 2.9e-06 26.9 0.3 0.0057 16.4 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC34351.1 - 8.3e-06 26.3 0.0 0.0053 17.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGC34351.1 - 0.00011 21.5 23.4 0.00011 21.5 23.4 3.7 2 2 0 2 2 2 2 ABC-2 family transporter protein AAA_25 PF13481.6 EGC34351.1 - 0.00054 19.6 0.1 0.0032 17.1 0.1 2.0 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGC34351.1 - 0.00064 19.6 0.0 1.5 8.6 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGC34351.1 - 0.0025 18.1 0.1 0.44 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGC34351.1 - 0.0078 16.3 0.2 6 7.0 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase cobW PF02492.19 EGC34351.1 - 0.011 15.3 0.1 0.46 10.1 0.0 2.4 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_18 PF13238.6 EGC34351.1 - 0.02 15.4 0.8 0.75 10.3 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_33 PF13671.6 EGC34351.1 - 0.034 14.3 0.1 1.2 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC34351.1 - 0.035 13.8 0.1 2 8.1 0.2 2.3 2 0 0 2 2 2 0 AAA domain Colicin-DNase PF12639.7 EGC34351.1 - 0.094 13.5 0.2 0.094 13.5 0.2 2.2 2 0 0 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin AAA PF00004.29 EGC34351.1 - 0.098 13.1 0.3 9.2 6.7 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.15 EGC34351.1 - 0.2 11.5 0.6 41 4.0 0.0 3.2 3 0 0 3 3 3 0 NTPase NACHT PF05729.12 EGC34351.1 - 0.21 11.5 0.5 6.3 6.7 0.3 2.4 2 0 0 2 2 2 0 NACHT domain Rad17 PF03215.15 EGC34351.1 - 0.25 11.2 1.7 4.2 7.2 0.0 2.7 3 0 0 3 3 3 0 Rad17 P-loop domain Chromosome_seg PF13889.6 EGC34352.1 - 0.1 12.8 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Chromosome segregation during meiosis Glyco_hydro_38N PF01074.22 EGC34354.1 - 8.6e-72 241.9 3.9 1.8e-71 240.9 3.9 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC34354.1 - 6.9e-15 55.0 0.0 1.6e-14 53.8 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGC34354.1 - 7.5e-14 52.3 0.3 1.4e-13 51.4 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Glyco_hydro38C2 PF17677.1 EGC34354.1 - 0.019 15.1 0.1 0.069 13.3 0.1 2.0 1 0 0 1 1 1 0 Glycosyl hydrolases family 38 C-terminal beta sandwich domain PilN_bio_d PF18222.1 EGC34354.1 - 0.12 12.8 0.2 0.76 10.2 0.1 2.3 3 0 0 3 3 3 0 PilN biogenesis protein dimerization domain TIG PF01833.24 EGC34355.1 - 4.3e-15 55.6 26.7 1.2e-05 25.3 6.7 4.3 4 0 0 4 4 4 4 IPT/TIG domain Phage_T7_tail PF03906.14 EGC34355.1 - 0.068 12.8 0.1 3 7.5 0.0 2.4 2 0 0 2 2 2 0 Phage T7 tail fibre protein Cupin_8 PF13621.6 EGC34356.1 - 2.8e-31 109.2 2.4 3.5e-31 108.8 2.4 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.22 EGC34356.1 - 3.3e-09 37.2 0.1 7.5e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.22 EGC34356.1 - 0.00078 19.1 0.0 0.0016 18.0 0.0 1.5 1 1 0 1 1 1 1 Cupin GPI PF06560.11 EGC34356.1 - 0.016 14.5 1.9 0.022 14.0 0.3 1.9 1 1 1 2 2 2 0 Glucose-6-phosphate isomerase (GPI) Cupin_2 PF07883.11 EGC34356.1 - 0.06 13.1 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 Cupin domain C2 PF00168.30 EGC34357.1 - 4.6e-17 62.2 0.0 8.1e-17 61.4 0.0 1.4 1 0 0 1 1 1 1 C2 domain Methyltransf_2 PF00891.18 EGC34358.1 - 3.2e-34 118.1 0.0 4.5e-34 117.6 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain LptF_LptG PF03739.14 EGC34358.1 - 0.018 13.9 2.0 0.035 13.0 2.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG RrnaAD PF00398.20 EGC34358.1 - 0.033 13.2 0.0 0.054 12.6 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_12 PF08242.12 EGC34358.1 - 0.059 14.1 0.1 0.31 11.8 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGC34358.1 - 0.1 12.1 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain MpPF26 PF07666.11 EGC34358.1 - 0.13 12.4 4.8 0.25 11.4 4.8 1.4 1 0 0 1 1 1 0 M penetrans paralogue family 26 Methyltransf_31 PF13847.6 EGC34358.1 - 0.15 11.9 0.5 0.78 9.5 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain DUF3938 PF13074.6 EGC34358.1 - 0.21 11.9 0.9 0.63 10.3 0.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Abhydrolase_1 PF00561.20 EGC34359.1 - 8.8e-13 48.5 0.0 1.4e-12 47.8 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34359.1 - 4.7e-10 39.2 0.0 1.1e-09 37.9 0.0 1.7 1 1 0 1 1 1 1 Serine aminopeptidase, S33 PGAP1 PF07819.13 EGC34359.1 - 1.9e-07 31.1 0.1 4.9e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.7 EGC34359.1 - 3.7e-07 31.0 0.0 4.4e-07 30.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.16 EGC34359.1 - 5.5e-05 22.7 0.4 0.02 14.5 0.1 2.4 2 0 0 2 2 2 2 Partial alpha/beta-hydrolase lipase region DUF676 PF05057.14 EGC34359.1 - 0.00029 20.4 0.3 0.00053 19.6 0.3 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.25 EGC34359.1 - 0.0012 18.8 0.0 0.0022 17.9 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) LIDHydrolase PF10230.9 EGC34359.1 - 0.0044 16.6 0.5 0.029 14.0 0.2 2.1 2 0 0 2 2 2 1 Lipid-droplet associated hydrolase Esterase PF00756.20 EGC34359.1 - 0.0054 16.4 0.0 0.012 15.3 0.0 1.6 1 1 0 1 1 1 1 Putative esterase DUF1749 PF08538.10 EGC34359.1 - 0.0062 15.7 0.0 0.04 13.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Palm_thioest PF02089.15 EGC34359.1 - 0.011 15.6 1.3 0.14 12.0 0.0 2.4 1 1 1 2 2 2 0 Palmitoyl protein thioesterase BAAT_C PF08840.11 EGC34359.1 - 0.016 15.1 0.0 0.025 14.5 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.7 EGC34359.1 - 0.024 14.4 0.0 0.12 12.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family Cutinase PF01083.22 EGC34359.1 - 0.2 11.6 0.0 0.33 10.9 0.0 1.3 1 0 0 1 1 1 0 Cutinase Neur_chan_memb PF02932.16 EGC34360.1 - 1.4 8.9 19.9 1.9 8.5 3.6 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V_ATPase_I PF01496.19 EGC34360.1 - 4.6 5.0 36.5 1.8 6.4 3.7 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FUSC PF04632.12 EGC34360.1 - 8.4 4.8 7.5 9.6 4.6 7.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Tim17 PF02466.19 EGC34361.1 - 1.1e-25 90.2 2.6 1.3e-25 90.0 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_Omp PF13488.6 EGC34361.1 - 0.4 10.7 9.2 1.8 8.6 3.8 2.2 2 0 0 2 2 2 0 Glycine zipper ERM PF00769.19 EGC34362.1 - 0.00023 21.1 15.7 0.00023 21.1 15.7 3.5 1 1 2 3 3 3 1 Ezrin/radixin/moesin family TSC22 PF01166.18 EGC34362.1 - 0.00062 20.0 4.3 0.00062 20.0 4.3 4.9 5 0 0 5 5 5 2 TSC-22/dip/bun family DUF2538 PF10804.8 EGC34362.1 - 1.1 9.0 6.6 0.097 12.4 1.8 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2538) TolA_bind_tri PF16331.5 EGC34363.1 - 0.016 15.3 5.0 0.052 13.6 0.1 3.5 3 1 0 3 3 3 0 TolA binding protein trimerisation SbcD_C PF12320.8 EGC34363.1 - 0.036 14.3 1.0 0.036 14.3 1.0 4.6 4 2 1 5 5 5 0 Type 5 capsule protein repressor C-terminal domain Phasin_2 PF09361.10 EGC34363.1 - 1.1 9.5 15.5 0.29 11.4 6.5 4.0 4 1 0 4 4 4 0 Phasin protein Atg14 PF10186.9 EGC34363.1 - 3.9 6.5 40.3 1.2 8.2 22.8 3.1 3 0 0 3 3 3 0 Vacuolar sorting 38 and autophagy-related subunit 14 ADSL_C PF10397.9 EGC34363.1 - 4.3 8.0 0.0 4.3 8.0 0.0 3.5 4 0 0 4 4 4 0 Adenylosuccinate lyase C-terminus OmpH PF03938.14 EGC34363.1 - 5.7 7.3 63.8 0.19 12.1 0.5 4.7 3 2 1 4 4 4 0 Outer membrane protein (OmpH-like) RA PF00788.23 EGC34364.1 - 3.6e-06 27.5 0.1 3.7e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PI3K_rbd PF00794.18 EGC34364.1 - 0.0024 18.0 0.1 0.0025 18.0 0.1 1.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain Ras_bdg_2 PF14847.6 EGC34364.1 - 0.0049 17.2 0.2 0.0054 17.1 0.2 1.1 1 0 0 1 1 1 1 Ras-binding domain of Byr2 CH PF00307.31 EGC34365.1 - 2.8e-15 56.4 0.1 5.4e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Calponin homology (CH) domain CH_2 PF06294.11 EGC34365.1 - 0.036 14.2 0.0 0.073 13.2 0.0 1.5 1 0 0 1 1 1 0 CH-like domain in sperm protein DUF87 PF01935.17 EGC34365.1 - 0.57 10.2 2.7 1.1 9.3 2.7 1.5 1 0 0 1 1 1 0 Helicase HerA, central domain USP8_dimer PF08969.11 EGC34367.1 - 1.5e-26 92.9 3.1 1.5e-26 92.9 3.1 2.1 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.21 EGC34367.1 - 9.4e-20 70.8 0.1 9.4e-20 70.8 0.1 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGC34367.1 - 3.3e-06 26.8 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ARGLU PF15346.6 EGC34367.1 - 0.0022 17.9 20.4 0.0048 16.8 20.4 1.5 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 ALMT PF11744.8 EGC34367.1 - 3.2 6.5 6.3 4.5 6.0 6.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF5401 PF17380.2 EGC34367.1 - 5.1 5.0 21.6 7.3 4.5 21.6 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5401) DUF1682 PF07946.14 EGC34367.1 - 7.2 5.7 16.9 11 5.2 16.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) SID-1_RNA_chan PF13965.6 EGC34369.1 - 5e-82 276.2 30.4 5.9e-82 276.0 30.4 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 ATP-sulfurylase PF01747.17 EGC34370.1 - 4.2e-84 281.3 0.0 6.6e-84 280.6 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.20 EGC34370.1 - 6e-61 205.0 0.0 1e-60 204.2 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.6 EGC34370.1 - 6.4e-46 155.9 0.0 1e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_29 PF13555.6 EGC34370.1 - 0.00026 20.7 0.0 0.00065 19.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_33 PF13671.6 EGC34370.1 - 0.00094 19.4 0.0 0.0021 18.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC34370.1 - 0.0018 18.7 0.0 0.0032 17.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain CbiA PF01656.23 EGC34370.1 - 0.0021 18.1 0.0 0.005 16.9 0.0 1.5 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain KTI12 PF08433.10 EGC34370.1 - 0.0044 16.5 0.0 0.0078 15.7 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGC34370.1 - 0.0045 16.3 0.0 0.0091 15.3 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.6 EGC34370.1 - 0.0055 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain MeaB PF03308.16 EGC34370.1 - 0.009 15.0 0.0 0.014 14.3 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC_tran PF00005.27 EGC34370.1 - 0.018 15.5 0.1 0.054 14.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter AAA_28 PF13521.6 EGC34370.1 - 0.021 15.1 0.2 0.11 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain Torsin PF06309.11 EGC34370.1 - 0.025 14.7 0.0 0.047 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin Sigma54_activat PF00158.26 EGC34370.1 - 0.031 14.0 0.0 0.052 13.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RsgA_GTPase PF03193.16 EGC34370.1 - 0.045 13.6 0.5 0.091 12.7 0.0 1.6 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EGC34370.1 - 0.057 13.9 0.1 0.095 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC34370.1 - 0.15 12.3 0.0 0.27 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC34370.1 - 0.15 11.7 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.6 EGC34370.1 - 0.16 12.4 0.0 0.32 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3751 PF12571.8 EGC34370.1 - 0.16 12.0 0.0 0.3 11.1 0.0 1.4 1 0 0 1 1 1 0 Phage tail-collar fibre protein CLP1_P PF16575.5 EGC34370.1 - 0.16 11.7 0.0 0.32 10.8 0.0 1.4 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop NB-ARC PF00931.22 EGC34370.1 - 0.18 11.0 0.0 0.29 10.3 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IIGP PF05049.13 EGC34370.1 - 0.2 10.7 0.0 0.35 9.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) ParA PF10609.9 EGC34370.1 - 0.2 11.0 0.0 0.34 10.3 0.0 1.3 1 0 0 1 1 1 0 NUBPL iron-transfer P-loop NTPase Sod_Cu PF00080.20 EGC34371.1 - 1.1e-16 61.3 0.1 2.7e-16 60.0 0.1 1.7 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Terminase_6C PF17289.2 EGC34372.1 - 0.14 12.2 0.0 0.24 11.5 0.0 1.3 1 0 0 1 1 1 0 Terminase RNaseH-like domain DUF2972 PF11186.8 EGC34372.1 - 1.3 8.9 11.0 3.3 7.6 0.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2972) Aminotran_3 PF00202.21 EGC34373.1 - 3.2e-78 263.2 0.0 4e-78 262.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III HMGL-like PF00682.19 EGC34374.1 - 8.7e-58 196.0 0.0 1e-57 195.7 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Med6 PF04934.14 EGC34375.1 - 1.3e-43 148.0 2.5 2.1e-43 147.3 2.5 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component Period_C PF12114.8 EGC34375.1 - 0.028 14.0 0.2 0.044 13.4 0.2 1.3 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MMR_HSR1_C PF08438.10 EGC34376.1 - 1.6e-36 125.2 0.0 3.1e-36 124.4 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.23 EGC34376.1 - 1.3e-21 76.8 0.0 2.5e-21 75.9 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC34376.1 - 6.9e-09 35.4 0.0 2.1e-07 30.6 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.21 EGC34376.1 - 0.0036 17.3 0.0 0.0076 16.3 0.0 1.4 1 0 0 1 1 1 1 TGS domain YchF-GTPase_C PF06071.13 EGC34376.1 - 0.01 16.0 0.0 0.027 14.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF933) Dynamin_N PF00350.23 EGC34376.1 - 0.021 14.9 0.0 0.068 13.2 0.0 1.9 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.23 EGC34377.1 - 2.9e-06 27.3 4.8 1.8e-05 24.8 1.2 3.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGC34377.1 - 0.0018 17.8 0.1 0.075 12.5 0.0 2.9 3 0 0 3 3 3 1 P-loop containing dynein motor region MCM PF00493.23 EGC34377.1 - 0.007 15.5 1.7 0.02 14.0 0.0 2.5 3 0 0 3 3 3 1 MCM P-loop domain RsgA_GTPase PF03193.16 EGC34377.1 - 0.0096 15.8 0.3 0.041 13.8 0.3 2.1 1 1 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGC34377.1 - 0.0097 15.6 0.0 0.031 14.0 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EGC34377.1 - 0.016 14.8 0.0 0.016 14.8 0.0 2.5 3 1 0 3 3 3 0 Elongation factor Tu GTP binding domain T2SSE PF00437.20 EGC34377.1 - 0.092 11.8 0.0 0.19 10.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AIG1 PF04548.16 EGC34377.1 - 0.38 10.0 12.8 1.1 8.6 0.0 3.8 4 0 0 4 4 4 0 AIG1 family DUF3584 PF12128.8 EGC34378.1 - 0.00017 19.3 25.3 0.00021 19.0 25.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DUF3375 PF11855.8 EGC34378.1 - 0.00062 18.8 9.0 0.019 13.9 4.2 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3375) GAS PF13851.6 EGC34378.1 - 0.00085 18.7 39.7 0.076 12.4 12.6 2.7 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EGC34378.1 - 0.0019 18.3 3.7 0.0019 18.3 3.7 3.3 1 1 3 4 4 4 1 Protein of unknown function (DUF1664) FapA PF03961.13 EGC34378.1 - 0.0032 16.1 10.5 0.0032 16.1 10.5 2.8 1 1 2 3 3 3 1 Flagellar Assembly Protein A UPF0242 PF06785.11 EGC34378.1 - 0.0066 16.6 38.3 0.3 11.2 18.5 2.6 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0242) N-terminus Fib_alpha PF08702.10 EGC34378.1 - 0.0083 16.3 11.1 0.0083 16.3 11.1 3.6 1 1 3 4 4 4 1 Fibrinogen alpha/beta chain family HrpB7 PF09486.10 EGC34378.1 - 0.013 15.9 9.7 0.082 13.3 3.1 2.7 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) ADIP PF11559.8 EGC34378.1 - 0.016 15.3 9.5 0.016 15.3 9.5 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding APG6_N PF17675.1 EGC34378.1 - 0.017 15.6 36.4 0.045 14.3 13.5 2.9 1 1 2 3 3 3 0 Apg6 coiled-coil region BAR_3 PF16746.5 EGC34378.1 - 0.035 13.8 22.9 0.011 15.5 18.0 2.1 1 1 0 2 2 2 0 BAR domain of APPL family AAA_13 PF13166.6 EGC34378.1 - 0.036 12.7 33.6 0.018 13.7 27.1 2.0 1 1 1 2 2 2 0 AAA domain Spc7 PF08317.11 EGC34378.1 - 0.046 12.6 38.7 0.058 12.3 21.9 2.6 1 1 2 3 3 3 0 Spc7 kinetochore protein NPV_P10 PF05531.12 EGC34378.1 - 0.046 14.2 26.7 1.4 9.4 4.8 4.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein cwf21 PF08312.12 EGC34378.1 - 0.052 13.7 0.9 0.052 13.7 0.9 3.1 3 1 0 3 3 1 0 cwf21 domain DUF4763 PF15960.5 EGC34378.1 - 0.063 12.6 25.6 0.068 12.5 10.4 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4763) FUSC PF04632.12 EGC34378.1 - 0.07 11.7 1.5 0.096 11.2 1.5 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family KxDL PF10241.9 EGC34378.1 - 0.084 13.2 21.1 1.5 9.1 8.1 3.8 1 1 2 3 3 3 0 Uncharacterized conserved protein Transcrip_act PF04949.13 EGC34378.1 - 0.094 12.6 20.4 0.61 10.0 6.0 3.2 1 1 2 3 3 3 0 Transcriptional activator DUF724 PF05266.14 EGC34378.1 - 0.1 12.4 27.4 0.13 12.0 11.6 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF724) Bacillus_HBL PF05791.11 EGC34378.1 - 0.11 12.3 24.1 0.21 11.4 12.4 2.6 1 1 2 3 3 3 0 Bacillus haemolytic enterotoxin (HBL) DASH_Dad1 PF08649.10 EGC34378.1 - 0.11 12.7 0.4 0.11 12.7 0.4 4.3 3 1 1 4 4 4 0 DASH complex subunit Dad1 SlyX PF04102.12 EGC34378.1 - 0.12 13.1 21.5 2.6 8.7 2.9 4.1 2 1 2 4 4 3 0 SlyX MscS_porin PF12795.7 EGC34378.1 - 0.15 11.6 33.7 1.2 8.6 26.8 2.3 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain DUF948 PF06103.11 EGC34378.1 - 0.16 12.2 14.9 10 6.5 7.3 3.7 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HsbA PF12296.8 EGC34378.1 - 0.19 12.2 9.2 0.42 11.1 3.8 2.9 1 1 2 3 3 3 0 Hydrophobic surface binding protein A PI3K_P85_iSH2 PF16454.5 EGC34378.1 - 0.2 11.2 29.7 3.2 7.3 26.4 2.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain ING PF12998.7 EGC34378.1 - 0.27 11.8 24.9 0.43 11.2 9.9 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4315 PF14193.6 EGC34378.1 - 0.29 11.2 18.7 0.51 10.4 2.0 4.5 3 2 1 4 4 4 0 Domain of unknown function (DUF4315) FlaC_arch PF05377.11 EGC34378.1 - 0.38 11.2 25.1 4.8 7.7 1.0 5.2 4 1 1 5 5 4 0 Flagella accessory protein C (FlaC) Filament PF00038.21 EGC34378.1 - 0.49 9.9 32.2 0.56 9.7 13.0 3.3 1 1 1 3 3 3 0 Intermediate filament protein TMPIT PF07851.13 EGC34378.1 - 0.5 9.6 24.5 0.29 10.4 11.4 2.5 1 1 1 2 2 2 0 TMPIT-like protein Sec34 PF04136.15 EGC34378.1 - 0.5 10.2 21.1 0.6 10.0 4.2 2.9 1 1 0 2 2 2 0 Sec34-like family ERM PF00769.19 EGC34378.1 - 0.5 10.1 29.6 2.2 8.0 7.4 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF4407 PF14362.6 EGC34378.1 - 0.55 9.5 24.1 0.16 11.3 9.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF2203 PF09969.9 EGC34378.1 - 0.56 10.9 18.1 3.2 8.5 6.7 2.8 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) SOGA PF11365.8 EGC34378.1 - 0.67 11.1 16.3 0.14 13.3 7.5 3.1 1 1 2 3 3 3 0 Protein SOGA THOC7 PF05615.13 EGC34378.1 - 0.85 9.9 26.6 0.21 11.9 13.5 3.0 1 1 1 2 2 2 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.12 EGC34378.1 - 0.95 9.5 31.4 1.5 8.9 0.9 3.3 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4201 PF13870.6 EGC34378.1 - 1 9.1 36.2 0.054 13.2 20.4 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4201) Cluap1 PF10234.9 EGC34378.1 - 1.3 8.4 27.8 0.21 10.9 2.4 3.5 1 1 3 4 4 4 0 Clusterin-associated protein-1 Golgin_A5 PF09787.9 EGC34378.1 - 1.3 8.4 31.6 0.25 10.7 21.5 2.2 1 1 1 2 2 2 0 Golgin subfamily A member 5 IFT57 PF10498.9 EGC34378.1 - 1.6 7.6 30.7 2.3 7.1 13.6 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 TFR_dimer PF04253.15 EGC34378.1 - 1.6 8.9 10.4 1.1 9.3 1.2 3.3 1 1 4 5 5 4 0 Transferrin receptor-like dimerisation domain Cep57_MT_bd PF06657.13 EGC34378.1 - 1.6 9.2 21.2 0.086 13.3 2.7 4.2 2 2 2 4 4 3 0 Centrosome microtubule-binding domain of Cep57 Laminin_II PF06009.12 EGC34378.1 - 1.6 8.7 28.3 1.7 8.6 9.5 3.3 1 1 3 4 4 4 0 Laminin Domain II Fez1 PF06818.15 EGC34378.1 - 2 8.8 28.0 5.6 7.4 12.5 2.1 1 1 1 2 2 2 0 Fez1 Prefoldin PF02996.17 EGC34378.1 - 2.3 8.2 30.4 3.1 7.7 4.8 4.7 2 1 3 5 5 5 0 Prefoldin subunit DUF3450 PF11932.8 EGC34378.1 - 2.5 7.3 30.6 1.4 8.2 13.6 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) Spore_III_AB PF09548.10 EGC34378.1 - 3.1 7.9 16.7 6.4 6.9 3.5 2.6 1 1 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) DUF4472 PF14739.6 EGC34378.1 - 3.3 8.5 25.2 4.1 8.2 5.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4472) TMF_TATA_bd PF12325.8 EGC34378.1 - 3.3 7.9 29.6 23 5.2 16.8 3.6 1 1 2 3 3 3 0 TATA element modulatory factor 1 TATA binding HMMR_N PF15905.5 EGC34378.1 - 3.3 7.1 37.9 0.22 11.0 11.8 2.6 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor N-terminal CENP-F_leu_zip PF10473.9 EGC34378.1 - 3.6 7.6 34.9 11 6.1 8.0 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 GCN5L1 PF06320.13 EGC34378.1 - 3.8 7.7 26.4 3.3 7.9 6.2 3.9 2 1 2 4 4 4 0 GCN5-like protein 1 (GCN5L1) OmpH PF03938.14 EGC34378.1 - 3.8 7.8 36.2 14 6.0 12.9 3.2 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) Uteroglobin PF01099.17 EGC34378.1 - 4 7.8 12.1 2.4 8.5 3.8 2.6 2 0 0 2 2 2 0 Uteroglobin family DUF4200 PF13863.6 EGC34378.1 - 4 7.9 36.6 0.37 11.2 6.3 4.0 1 1 3 4 4 3 0 Domain of unknown function (DUF4200) Prominin PF05478.11 EGC34378.1 - 4.7 5.0 20.6 4.3 5.2 19.5 1.5 1 1 0 1 1 1 0 Prominin DUF4298 PF14131.6 EGC34378.1 - 5.1 7.1 17.7 3.4 7.7 1.2 3.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4298) T3SSipB PF16535.5 EGC34378.1 - 5.5 7.4 24.5 4.4 7.8 9.9 2.7 1 1 2 3 3 3 0 Type III cell invasion protein SipB Seryl_tRNA_N PF02403.22 EGC34378.1 - 5.9 7.2 37.9 5.4 7.3 4.9 4.1 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain ATG16 PF08614.11 EGC34378.1 - 6 7.0 30.9 0.84 9.8 14.6 2.3 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) CALCOCO1 PF07888.11 EGC34378.1 - 6.2 5.6 28.5 0.81 8.5 19.5 2.2 1 1 1 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF2968 PF11180.8 EGC34378.1 - 6.3 6.4 23.4 2.7 7.6 4.0 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF4140 PF13600.6 EGC34378.1 - 6.8 7.2 23.3 2.6 8.5 1.3 4.1 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DHR10 PF18595.1 EGC34378.1 - 6.9 6.8 31.5 4.7 7.3 15.1 3.3 1 1 1 2 2 2 0 Designed helical repeat protein 10 domain GLE1 PF07817.13 EGC34378.1 - 7.2 5.7 10.7 0.51 9.5 0.7 2.4 1 1 2 3 3 3 0 GLE1-like protein Lectin_N PF03954.14 EGC34378.1 - 7.5 6.3 14.8 0.54 10.0 0.5 3.5 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain HemX PF04375.14 EGC34378.1 - 7.6 5.7 28.0 4.2 6.6 1.1 2.9 1 1 2 3 3 3 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4795 PF16043.5 EGC34378.1 - 8.3 5.9 33.9 77 2.8 33.9 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4795) SHE3 PF17078.5 EGC34378.1 - 8.5 6.0 34.7 14 5.3 27.0 2.4 1 1 1 2 2 2 0 SWI5-dependent HO expression protein 3 MCPsignal PF00015.21 EGC34378.1 - 9.3 6.0 13.9 2.9 7.7 2.9 2.8 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain V_ATPase_I PF01496.19 EGC34378.1 - 9.8 3.9 22.5 1.7e+02 -0.1 22.2 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family DNA_pol_delta_4 PF04081.13 EGC34378.1 - 10 6.5 11.7 0.37 11.1 4.3 2.3 1 1 1 2 2 2 0 DNA polymerase delta, subunit 4 GAS PF13851.6 EGC34379.1 - 0.00018 20.9 10.9 0.00018 20.9 10.9 2.2 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding DUF1664 PF07889.12 EGC34379.1 - 0.00035 20.6 12.6 0.06 13.4 2.7 3.3 1 1 4 5 5 5 4 Protein of unknown function (DUF1664) DUF3939 PF13075.6 EGC34379.1 - 0.0018 18.3 4.4 0.32 11.0 0.2 3.2 2 1 1 3 3 3 1 Protein of unknown function (DUF3939) PI3K_P85_iSH2 PF16454.5 EGC34379.1 - 0.0045 16.6 7.7 0.0045 16.6 7.7 2.7 1 1 1 2 2 2 1 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain Baculo_PEP_C PF04513.12 EGC34379.1 - 0.0059 16.7 2.2 0.0083 16.2 1.0 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus MetOD2 PF18548.1 EGC34379.1 - 0.0059 16.7 0.4 0.0059 16.7 0.4 3.5 2 1 1 3 3 3 1 Metanogen output domain 2 ERM PF00769.19 EGC34379.1 - 0.0077 16.1 3.6 0.0077 16.1 3.6 1.9 2 0 0 2 2 2 1 Ezrin/radixin/moesin family Uds1 PF15456.6 EGC34379.1 - 0.0086 16.2 10.9 0.28 11.3 0.4 3.9 2 1 2 4 4 4 1 Up-regulated During Septation Cluap1 PF10234.9 EGC34379.1 - 0.011 15.1 11.1 0.018 14.5 11.1 1.5 1 1 0 1 1 1 0 Clusterin-associated protein-1 U62_UL91 PF17442.2 EGC34379.1 - 0.021 14.8 4.4 0.075 13.0 0.2 3.3 3 1 1 4 4 3 0 Functional domain of U62 and UL91 proteins ArAE_2_N PF10337.9 EGC34379.1 - 0.022 13.8 1.4 0.031 13.3 1.4 1.1 1 0 0 1 1 1 0 Putative ER transporter, 6TM, N-terminal SOGA PF11365.8 EGC34379.1 - 0.03 15.5 5.3 0.03 15.5 5.3 2.4 2 1 0 2 2 2 0 Protein SOGA betaPIX_CC PF16523.5 EGC34379.1 - 0.04 13.8 10.4 0.64 9.9 1.7 2.8 2 1 0 2 2 2 0 betaPIX coiled coil DUF2333 PF10095.9 EGC34379.1 - 0.046 12.7 0.5 0.18 10.8 0.5 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2333) CALCOCO1 PF07888.11 EGC34379.1 - 0.076 11.9 11.9 0.1 11.4 11.9 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF948 PF06103.11 EGC34379.1 - 0.14 12.4 2.3 0.66 10.3 0.1 2.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Fzo_mitofusin PF04799.13 EGC34379.1 - 0.14 11.7 7.5 0.18 11.3 2.6 2.8 1 1 2 3 3 3 0 fzo-like conserved region HIP1_clath_bdg PF16515.5 EGC34379.1 - 0.22 12.2 13.6 0.23 12.1 3.1 3.9 1 1 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 Tubulin-binding PF00418.19 EGC34379.1 - 0.36 10.9 1.9 0.51 10.4 0.0 2.2 3 0 0 3 3 1 0 Tau and MAP protein, tubulin-binding repeat Tropomyosin_1 PF12718.7 EGC34379.1 - 0.36 11.0 14.9 0.12 12.5 9.3 2.6 1 1 1 2 2 2 0 Tropomyosin like BLOC1_2 PF10046.9 EGC34379.1 - 0.43 10.9 14.0 0.21 11.9 2.6 3.9 2 1 2 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PCRF PF03462.18 EGC34379.1 - 0.46 10.3 8.8 3 7.7 1.0 2.6 1 1 2 3 3 3 0 PCRF domain Laminin_II PF06009.12 EGC34379.1 - 0.47 10.5 7.1 1.1 9.3 0.9 2.7 1 1 2 3 3 3 0 Laminin Domain II RNase_HII PF01351.18 EGC34379.1 - 0.58 10.0 4.3 0.63 9.9 3.4 1.6 1 1 0 1 1 1 0 Ribonuclease HII Syntaxin-6_N PF09177.11 EGC34379.1 - 0.64 10.6 8.8 0.49 11.0 1.9 3.4 1 1 2 3 3 3 0 Syntaxin 6, N-terminal MtrG PF04210.13 EGC34379.1 - 0.81 9.6 0.1 0.81 9.6 0.1 3.0 4 0 0 4 4 4 0 Tetrahydromethanopterin S-methyltransferase, subunit G CENP-F_leu_zip PF10473.9 EGC34379.1 - 0.83 9.7 19.7 0.091 12.8 10.4 2.8 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Nsp1_C PF05064.13 EGC34379.1 - 1.2 9.0 10.0 3.2 7.6 1.4 3.4 2 2 2 4 4 4 0 Nsp1-like C-terminal region Rootletin PF15035.6 EGC34379.1 - 1.2 9.1 13.5 7.4 6.5 6.6 2.5 1 1 1 2 2 2 0 Ciliary rootlet component, centrosome cohesion Exonuc_VII_L PF02601.15 EGC34379.1 - 1.7 8.1 9.5 15 5.0 9.4 2.0 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF16 PF01519.16 EGC34379.1 - 2.1 8.9 14.0 11 6.5 5.2 3.3 1 1 1 2 2 2 0 Protein of unknown function DUF16 Vac_Fusion PF02346.16 EGC34379.1 - 2.1 8.0 7.1 1.8 8.3 0.3 3.3 2 1 1 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 KxDL PF10241.9 EGC34379.1 - 2.5 8.4 12.9 0.16 12.3 0.5 3.4 3 2 0 3 3 3 0 Uncharacterized conserved protein Ku_C PF03730.14 EGC34379.1 - 2.6 8.8 6.2 0.68 10.7 0.3 2.8 2 1 1 3 3 2 0 Ku70/Ku80 C-terminal arm Occludin_ELL PF07303.13 EGC34379.1 - 2.6 8.8 14.5 2 9.2 3.3 3.2 2 1 1 3 3 3 0 Occludin homology domain S_4TM PF18159.1 EGC34379.1 - 4.3 6.6 7.4 0.18 11.1 0.3 2.2 3 0 0 3 3 3 0 SMODS-associating 4TM effector domain Cauli_DNA-bind PF03310.13 EGC34379.1 - 5.7 7.0 9.2 8.3 6.5 0.6 3.3 1 1 3 4 4 4 0 Caulimovirus DNA-binding protein TMPIT PF07851.13 EGC34379.1 - 6 6.0 12.5 1 8.6 4.7 2.4 1 1 2 3 3 3 0 TMPIT-like protein DUF3450 PF11932.8 EGC34379.1 - 7.5 5.8 8.9 1.3 8.3 3.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) FlxA PF14282.6 EGC34379.1 - 8.7 6.4 11.7 1.4 9.0 0.8 2.9 2 1 1 3 3 3 0 FlxA-like protein SlyX PF04102.12 EGC34379.1 - 8.8 7.0 12.5 2.6 8.7 1.1 4.3 1 1 3 5 5 5 0 SlyX APG6_N PF17675.1 EGC34379.1 - 9.4 6.8 16.4 1.2e+03 -0.1 16.4 2.4 1 1 0 1 1 1 0 Apg6 coiled-coil region Gly_acyl_tr_N PF06021.11 EGC34380.1 - 0.011 15.9 1.7 0.011 15.9 1.7 1.6 2 0 0 2 2 2 0 Aralkyl acyl-CoA:amino acid N-acyltransferase T3SchapCesA PF11439.8 EGC34380.1 - 0.042 14.0 0.4 0.099 12.8 0.4 1.6 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA DUF5640 PF18692.1 EGC34381.1 - 0.027 14.5 0.3 0.056 13.5 0.1 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5640) CMAS PF02353.20 EGC34382.1 - 1e-85 287.4 0.6 1.4e-85 287.0 0.6 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_11 PF08241.12 EGC34382.1 - 3.4e-09 37.2 0.0 7.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34382.1 - 2.7e-08 34.4 0.0 9.2e-08 32.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34382.1 - 1.7e-07 31.2 0.0 2.8e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC34382.1 - 7.6e-06 25.8 0.0 1.4e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC34382.1 - 7.4e-05 23.4 0.0 0.00018 22.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EGC34382.1 - 0.098 12.3 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 DNA methylase Methyltransf_24 PF13578.6 EGC34382.1 - 0.13 13.3 0.0 0.37 11.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain SAP30_Sin3_bdg PF13867.6 EGC34383.1 - 1.2e-18 67.1 0.1 2e-18 66.4 0.1 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC48_2 PF02933.17 EGC34383.1 - 0.092 12.5 0.4 0.21 11.4 0.0 1.7 2 0 0 2 2 2 0 Cell division protein 48 (CDC48), domain 2 LRR_4 PF12799.7 EGC34384.1 - 4.3e-34 116.0 41.0 1.5e-08 34.8 0.9 6.4 3 1 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC34384.1 - 3.8e-26 91.6 22.1 1.7e-10 40.7 0.5 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_8 PF13855.6 EGC34384.1 - 1.2e-25 89.0 28.7 1e-08 34.8 3.8 5.1 2 1 2 5 5 5 5 Leucine rich repeat LRR_6 PF13516.6 EGC34384.1 - 2.4e-08 33.4 21.7 0.26 11.4 0.4 7.8 8 0 0 8 8 8 4 Leucine Rich repeat LRR_1 PF00560.33 EGC34384.1 - 0.0034 17.7 27.9 4.2 8.3 0.1 9.7 9 3 1 10 10 10 1 Leucine Rich Repeat LRR_2 PF07723.13 EGC34384.1 - 0.074 13.7 2.1 1.8e+02 3.0 0.0 5.0 5 0 0 5 5 5 0 Leucine Rich Repeat CBM49 PF09478.10 EGC34385.1 - 1.2e-16 60.8 0.0 1.6e-16 60.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF726 PF05277.12 EGC34387.1 - 0.073 12.0 0.0 0.15 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Snapin_Pallidin PF14712.6 EGC34388.1 - 1.7e-14 54.0 9.7 1.7e-14 54.0 9.7 2.9 3 1 0 3 3 3 1 Snapin/Pallidin DUF4407 PF14362.6 EGC34388.1 - 5.5 6.2 13.4 8.8 5.6 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) zf-CCCH PF00642.24 EGC34389.1 - 1.3e-06 28.2 2.1 2.5e-06 27.3 2.1 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGC34389.1 - 2e-06 27.6 4.5 3.7e-06 26.8 4.5 1.5 1 0 0 1 1 1 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGC34389.1 - 2.1e-06 27.4 1.0 4.6e-06 26.3 1.0 1.6 1 0 0 1 1 1 1 CCCH-type zinc finger zf-RanBP PF00641.18 EGC34389.1 - 0.00014 21.1 1.3 0.00014 21.1 1.3 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-C6H2 PF15801.5 EGC34389.1 - 0.0012 19.1 7.8 0.0037 17.6 7.8 1.8 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGC34389.1 - 0.0068 16.5 9.1 0.018 15.1 9.1 1.8 1 0 0 1 1 1 1 MYND finger zf-CCCH_2 PF14608.6 EGC34389.1 - 0.02 15.3 1.8 0.041 14.4 1.8 1.5 1 0 0 1 1 1 0 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGC34389.1 - 0.026 15.2 0.1 0.026 15.2 0.1 4.7 5 2 0 5 5 5 0 Torus domain HGTP_anticodon PF03129.20 EGC34389.1 - 0.036 14.2 0.2 0.11 12.6 0.2 2.0 1 0 0 1 1 1 0 Anticodon binding domain RAP1 PF07218.11 EGC34390.1 - 3.9 5.6 10.7 3.6 5.7 10.7 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) UNC80 PF15778.5 EGC34391.1 - 0.066 12.8 0.2 0.13 11.8 0.2 1.4 1 0 0 1 1 1 0 Cation channel complex component UNC80 PAPS_reduct PF01507.19 EGC34391.1 - 0.36 10.9 5.9 1.2 9.2 0.4 2.4 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family MMR_HSR1 PF01926.23 EGC34392.1 - 0.00012 22.1 0.3 0.00073 19.6 0.1 2.2 2 0 0 2 2 2 1 50S ribosome-binding GTPase Septin PF00735.18 EGC34392.1 - 0.00016 21.0 2.1 0.00016 21.0 2.1 2.4 2 1 0 2 2 2 1 Septin VWA_2 PF13519.6 EGC34392.1 - 0.00023 21.8 0.0 0.0012 19.5 0.0 2.2 1 1 0 1 1 1 1 von Willebrand factor type A domain RsgA_GTPase PF03193.16 EGC34392.1 - 0.0031 17.4 1.0 0.31 10.9 0.2 2.6 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGC34392.1 - 0.0084 16.2 1.9 1.2 9.2 0.1 2.8 2 0 0 2 2 2 2 Dynamin family YjfB_motility PF14070.6 EGC34392.1 - 0.024 14.8 0.2 0.066 13.4 0.0 1.8 2 0 0 2 2 2 0 Putative motility protein DUF5461 PF17545.2 EGC34392.1 - 0.062 13.6 1.3 0.5 10.7 0.0 3.2 4 0 0 4 4 4 0 Family of unknown function (DUF5461) AAA_16 PF13191.6 EGC34392.1 - 0.19 12.1 0.0 0.36 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain VWA_2 PF13519.6 EGC34393.1 - 2.3e-06 28.2 0.0 5.9e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Asn_synthase PF00733.21 EGC34394.1 - 3.6e-76 257.1 0.0 4.8e-76 256.7 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGC34394.1 - 1.3e-44 151.0 0.0 2e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC34394.1 - 1.6e-37 128.7 0.0 2.4e-37 128.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC34394.1 - 0.00019 21.0 0.0 0.00036 20.1 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein FmdE PF02663.14 EGC34394.1 - 0.12 12.4 0.0 0.32 11.0 0.0 1.7 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Cupin_8 PF13621.6 EGC34395.1 - 8e-48 163.4 2.3 3.5e-47 161.3 1.2 2.0 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.12 EGC34395.1 - 4.3e-12 46.1 0.0 9.3e-11 41.8 0.0 2.3 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGC34395.1 - 0.00026 21.4 0.0 0.001 19.5 0.0 2.1 1 1 0 1 1 1 1 JmjC domain, hydroxylase DUF228 PF02989.14 EGC34395.1 - 0.025 14.4 0.0 0.043 13.6 0.0 1.4 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Cupin_2 PF07883.11 EGC34395.1 - 0.029 14.1 0.0 0.066 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain ARD PF03079.14 EGC34395.1 - 0.23 11.7 1.2 0.8 9.9 0.0 2.4 3 0 0 3 3 3 0 ARD/ARD' family DUF5497 PF17601.2 EGC34395.1 - 0.32 11.3 5.6 3.5 8.0 0.1 3.9 3 1 1 4 4 4 0 Family of unknown function (DUF5497) SPC22 PF04573.12 EGC34398.1 - 2.1e-35 121.8 1.2 2.3e-35 121.6 1.2 1.0 1 0 0 1 1 1 1 Signal peptidase subunit RNF111_N PF15303.6 EGC34399.1 - 0.11 12.2 2.7 0.14 11.9 2.7 1.1 1 0 0 1 1 1 0 E3 ubiquitin-protein ligase Arkadia N-terminus Atg8 PF02991.16 EGC34400.1 - 2.7e-15 56.4 0.8 3e-15 56.3 0.8 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HlyIII PF03006.20 EGC34402.1 - 3.2e-38 131.7 28.3 4.5e-38 131.2 28.3 1.2 1 0 0 1 1 1 1 Haemolysin-III related Anticodon_1 PF08264.13 EGC34402.1 - 5.9 6.8 6.8 2.8 7.9 2.4 2.2 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA NUMOD1 PF07453.13 EGC34403.1 - 2.2 8.6 12.3 0.77 10.1 0.5 3.9 3 0 0 3 3 3 0 NUMOD1 domain Lebercilin PF15619.6 EGC34404.1 - 0.01 15.5 16.9 0.01 15.5 16.9 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease MtrG PF04210.13 EGC34404.1 - 0.055 13.3 2.1 2.2 8.2 0.2 2.3 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G DUF1664 PF07889.12 EGC34404.1 - 3.8 7.5 20.5 0.022 14.8 4.1 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF1664) COG2 PF06148.11 EGC34404.1 - 5.2 7.2 14.9 5.1 7.2 1.8 2.7 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CENP-F_leu_zip PF10473.9 EGC34404.1 - 9.2 6.3 30.3 2.3 8.2 17.1 3.1 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 EGF_2 PF07974.13 EGC34405.1 - 0.11 12.9 15.1 0.042 14.2 11.8 2.0 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 EGC34405.1 - 0.21 11.7 5.8 0.55 10.3 5.8 1.7 1 0 0 1 1 1 0 Tenascin EGF domain TPR_11 PF13414.6 EGC34406.1 - 0.28 10.9 3.9 0.18 11.5 0.9 2.1 2 0 0 2 2 2 0 TPR repeat U5_2-snRNA_bdg PF10597.9 EGC34407.1 - 0.049 13.7 0.6 0.15 12.1 0.0 2.1 3 1 0 3 3 3 0 U5-snRNA binding site 2 of PrP8 DUF1689 PF07954.11 EGC34408.1 - 0.0096 16.3 1.6 0.013 15.9 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1689) DUF2706 PF10913.8 EGC34408.1 - 0.077 12.8 0.3 0.17 11.7 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2706) RhoGAP PF00620.27 EGC34410.1 - 6.8e-47 159.1 0.0 3.6e-46 156.8 0.0 2.3 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGC34410.1 - 8.3e-10 39.1 1.5 8.3e-10 39.1 1.5 2.5 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.17 EGC34410.1 - 6.4e-06 25.7 0.2 2e-05 24.1 0.0 2.0 2 0 0 2 2 2 1 Variant SH3 domain SH3_9 PF14604.6 EGC34410.1 - 1.2e-05 25.0 0.1 2.3e-05 24.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC34410.1 - 0.00016 21.2 0.2 0.00038 20.0 0.2 1.7 1 0 0 1 1 1 1 SH3 domain OrfB_IS605 PF01385.19 EGC34410.1 - 1.1 9.4 7.5 0.3 11.3 1.6 2.3 2 0 0 2 2 2 0 Probable transposase APG6_N PF17675.1 EGC34410.1 - 2.2 8.8 21.2 0.031 14.8 3.6 2.7 2 0 0 2 2 2 0 Apg6 coiled-coil region Mucin PF01456.17 EGC34410.1 - 7.6 6.5 9.3 19 5.2 9.3 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein UPF0449 PF15136.6 EGC34410.1 - 8.8 6.9 16.7 1.6 9.2 0.5 3.8 3 1 1 4 4 4 0 Uncharacterised protein family UPF0449 OmpH PF03938.14 EGC34410.1 - 9.5 6.6 24.8 2.4 8.5 13.2 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) FKBP_C PF00254.28 EGC34411.1 - 3.8e-27 94.4 0.0 4.2e-27 94.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RhoGAP PF00620.27 EGC34413.1 - 7.2e-36 123.3 0.0 2e-35 121.8 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain LRR_6 PF13516.6 EGC34413.1 - 5e-08 32.4 19.9 0.00033 20.5 0.2 7.6 7 0 0 7 7 7 3 Leucine Rich repeat Carm_PH PF17888.1 EGC34413.1 - 2.7e-07 30.9 0.7 8e-07 29.3 0.7 1.9 1 0 0 1 1 1 1 Carmil pleckstrin homology domain LRR_4 PF12799.7 EGC34413.1 - 0.49 10.9 0.0 0.49 10.9 0.0 7.9 8 1 1 9 9 9 0 Leucine Rich repeats (2 copies) DEC-1_N PF04625.13 EGC34414.1 - 0.029 13.4 3.7 0.034 13.2 3.7 1.0 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region CCDC24 PF15669.5 EGC34414.1 - 0.081 12.8 0.1 0.084 12.7 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family MSA-2c PF12238.8 EGC34414.1 - 0.1 12.6 9.8 0.13 12.3 9.8 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c ORC6 PF05460.13 EGC34414.1 - 4.4 6.5 8.0 5.1 6.3 8.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) QWRF PF04484.12 EGC34414.1 - 6.9 6.3 7.3 8.2 6.1 7.3 1.0 1 0 0 1 1 1 0 QWRF family Proteasome PF00227.26 EGC34415.1 - 6.7e-61 205.1 0.2 8.8e-61 204.7 0.2 1.2 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC34415.1 - 4.9e-15 54.9 0.1 9.8e-15 53.9 0.1 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Exo70 PF03081.15 EGC34417.1 - 5.4e-49 167.2 19.0 7.4e-49 166.8 15.4 2.3 2 0 0 2 2 2 1 Exo70 exocyst complex subunit DASH_Dad2 PF08654.10 EGC34417.1 - 0.0073 16.7 0.2 0.0073 16.7 0.2 2.6 3 0 0 3 3 3 1 DASH complex subunit Dad2 USP8_interact PF08941.10 EGC34417.1 - 0.14 12.0 0.5 0.48 10.2 0.5 1.9 1 0 0 1 1 1 0 USP8 interacting RhoGAP PF00620.27 EGC34418.1 - 7.1e-39 133.1 0.2 7.1e-39 133.1 0.2 2.5 3 0 0 3 3 3 1 RhoGAP domain Ribosomal_L29 PF00831.23 EGC34418.1 - 0.012 15.6 3.0 0.9 9.6 0.2 2.9 2 0 0 2 2 2 0 Ribosomal L29 protein DUF1192 PF06698.11 EGC34418.1 - 0.017 15.2 0.8 0.82 9.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Vps5 PF09325.10 EGC34419.1 - 2e-57 194.5 9.5 4.3e-57 193.4 9.5 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.24 EGC34419.1 - 2e-23 82.5 0.0 1.1e-22 80.2 0.0 2.3 2 0 0 2 2 2 1 PX domain Phage_Mu_Gam PF07352.12 EGC34419.1 - 0.024 14.6 2.5 0.066 13.1 0.5 2.5 2 1 0 2 2 2 0 Bacteriophage Mu Gam like protein KdgM PF06178.13 EGC34419.1 - 1.2 8.7 6.5 0.38 10.3 1.8 2.1 2 0 0 2 2 2 0 Oligogalacturonate-specific porin protein (KdgM) FNIP PF05725.12 EGC34420.1 - 6e-59 196.0 41.2 4e-13 49.3 0.3 7.7 6 1 3 9 9 9 8 FNIP Repeat LRR_5 PF13306.6 EGC34420.1 - 0.0064 16.5 10.4 1 9.3 0.5 4.4 2 2 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) Ribosomal_L38e PF01781.18 EGC34420.1 - 0.13 12.4 1.2 4.2 7.6 0.2 2.8 1 1 1 2 2 2 0 Ribosomal L38e protein family SBDS_C PF09377.10 EGC34421.1 - 8.2e-36 122.5 2.5 8.2e-36 122.5 2.5 2.1 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.18 EGC34421.1 - 2.2e-30 104.6 1.0 5.1e-30 103.4 1.0 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein SirA PF10747.9 EGC34421.1 - 2.7 8.3 6.0 8.3 6.7 1.0 2.3 2 0 0 2 2 2 0 Sporulation inhibitor of replication protein SirA Aminotran_1_2 PF00155.21 EGC34422.1 - 4.2e-12 45.9 0.0 5.7e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.7 EGC34422.1 - 1.1e-05 24.4 0.0 1.7e-05 23.9 0.0 1.1 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase LSM PF01423.22 EGC34423.1 - 2.2e-16 59.3 0.4 3.4e-16 58.7 0.4 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC34423.1 - 0.011 15.8 0.0 0.017 15.2 0.0 1.3 1 0 0 1 1 1 0 Ataxin 2 SM domain AAA PF00004.29 EGC34424.1 - 9.7e-12 45.5 0.2 3.6e-11 43.6 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.15 EGC34424.1 - 5e-05 23.3 5.5 0.003 17.5 0.0 3.5 2 1 1 3 3 3 2 Rad17 P-loop domain AAA_14 PF13173.6 EGC34424.1 - 5e-05 23.3 0.0 5e-05 23.3 0.0 2.9 3 1 1 4 4 4 1 AAA domain RuvB_N PF05496.12 EGC34424.1 - 8.8e-05 22.3 0.0 0.00025 20.8 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_28 PF13521.6 EGC34424.1 - 0.00092 19.5 0.1 0.0018 18.5 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGC34424.1 - 0.0014 18.9 0.2 0.017 15.4 0.2 2.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC34424.1 - 0.0031 17.5 0.0 0.0088 16.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC34424.1 - 0.0032 17.9 0.0 0.0088 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGC34424.1 - 0.0041 17.7 0.0 0.0041 17.7 0.0 3.7 4 0 0 4 4 3 1 AAA domain AAA_33 PF13671.6 EGC34424.1 - 0.0052 16.9 0.0 0.016 15.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGC34424.1 - 0.0078 15.5 0.0 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin PBP1_TM PF14812.6 EGC34424.1 - 0.012 15.9 1.4 0.012 15.9 1.4 3.1 3 0 0 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NACHT PF05729.12 EGC34424.1 - 0.019 14.9 0.2 0.13 12.2 0.1 2.3 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.15 EGC34424.1 - 0.019 14.9 1.1 0.12 12.3 0.2 2.4 1 1 1 2 2 2 0 NTPase TsaE PF02367.17 EGC34424.1 - 0.025 14.6 0.0 0.053 13.5 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_19 PF13245.6 EGC34424.1 - 0.075 13.4 2.7 0.25 11.6 0.9 2.5 2 1 1 3 3 3 0 AAA domain AAA_30 PF13604.6 EGC34424.1 - 0.11 12.2 0.0 0.49 10.1 0.0 2.0 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGC34424.1 - 0.48 9.7 4.9 0.12 11.7 0.3 2.2 2 1 0 2 2 2 0 KaiC MJ1316 PF04457.12 EGC34425.1 - 3.8e-08 34.0 0.1 1.4e-07 32.2 0.1 2.0 1 1 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain DUF3915 PF13054.6 EGC34425.1 - 0.075 13.0 8.8 0.49 10.4 7.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) Eapp_C PF10238.9 EGC34425.1 - 0.36 10.9 7.0 0.037 14.1 1.7 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein PDCD2_C PF04194.13 EGC34425.1 - 0.45 10.6 14.2 0.047 13.8 6.2 2.2 2 0 0 2 2 2 0 Programmed cell death protein 2, C-terminal putative domain Arabino_trans_C PF14896.6 EGC34425.1 - 0.74 8.8 3.5 1.1 8.2 3.5 1.1 1 0 0 1 1 1 0 EmbC C-terminal domain Atrophin-1 PF03154.15 EGC34425.1 - 1.4 7.1 18.4 2 6.6 18.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family GOLD_2 PF13897.6 EGC34425.1 - 2.1 8.8 8.7 7.5 7.1 3.6 2.4 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking Trypan_PARP PF05887.11 EGC34425.1 - 2.2 8.2 8.9 0.45 10.5 5.1 1.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Ribosomal_S25 PF03297.15 EGC34425.1 - 2.5 8.3 20.1 0.17 12.1 13.4 2.1 2 0 0 2 2 2 0 S25 ribosomal protein RNA_pol_Rpc4 PF05132.14 EGC34425.1 - 2.7 8.4 12.9 0.69 10.3 7.0 2.0 2 0 0 2 2 2 0 RNA polymerase III RPC4 Presenilin PF01080.17 EGC34425.1 - 3.2 6.4 11.1 3.8 6.2 11.1 1.1 1 0 0 1 1 1 0 Presenilin Eisosome1 PF12757.7 EGC34425.1 - 8.9 6.6 19.5 3.7 7.8 16.4 1.8 2 0 0 2 2 2 0 Eisosome protein 1 ketoacyl-synt PF00109.26 EGC34426.1 - 2.9e-61 207.2 0.0 5.1e-61 206.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34426.1 - 1.7e-42 146.1 0.0 2.7e-29 102.7 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain NAD_binding_4 PF07993.12 EGC34426.1 - 1.7e-42 145.4 0.0 3.7e-42 144.3 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC34426.1 - 2.1e-32 111.6 0.0 8.6e-32 109.6 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34426.1 - 7.9e-27 94.3 0.1 2.6e-24 86.1 0.1 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC34426.1 - 3.4e-21 75.8 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC34426.1 - 7.6e-21 74.7 3.2 2.3e-20 73.2 0.0 3.8 5 0 0 5 5 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC34426.1 - 8.4e-16 58.4 0.1 3.4e-15 56.5 0.1 2.2 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGC34426.1 - 1.6e-09 37.6 0.1 1.6e-06 27.7 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 EGC34426.1 - 8.9e-09 36.5 0.0 2.6e-08 35.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC34426.1 - 7.2e-06 25.8 0.1 1.7e-05 24.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC34426.1 - 1.3e-05 25.4 0.0 7.7e-05 23.0 0.0 2.2 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGC34426.1 - 9e-05 23.0 0.0 0.00032 21.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34426.1 - 0.00077 19.3 0.0 0.0021 17.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC34426.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain GDP_Man_Dehyd PF16363.5 EGC34426.1 - 0.0017 17.8 5.5 0.28 10.6 0.0 2.8 3 0 0 3 3 3 2 GDP-mannose 4,6 dehydratase Methyltransf_31 PF13847.6 EGC34426.1 - 0.031 14.1 3.8 0.12 12.2 0.0 3.5 3 0 0 3 3 3 0 Methyltransferase domain adh_short PF00106.25 EGC34426.1 - 0.034 13.6 0.6 0.14 11.5 0.1 2.2 2 0 0 2 2 2 0 short chain dehydrogenase ketoacyl-synt PF00109.26 EGC34427.1 - 3e-63 213.8 0.0 5.1e-63 213.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC34427.1 - 7.1e-40 137.5 0.0 1.4e-39 136.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC34427.1 - 5.3e-33 113.5 0.0 2.4e-32 111.4 0.0 2.2 3 0 0 3 3 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC34427.1 - 5.3e-24 85.1 0.1 1.2e-23 84.0 0.1 1.6 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC34427.1 - 1.1e-22 80.6 0.0 1.7e-22 80.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC34427.1 - 4.9e-21 75.3 4.0 7.5e-21 74.7 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC34427.1 - 3.7e-10 40.3 0.5 2.4e-09 37.6 0.5 2.6 1 1 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC34427.1 - 1.5e-09 39.0 0.0 4.5e-09 37.5 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EGC34427.1 - 3.8e-06 27.5 0.0 2.1e-05 25.2 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.12 EGC34427.1 - 4.9e-06 26.4 0.0 1.3e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC34427.1 - 3.6e-05 24.3 0.0 0.00011 22.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC34427.1 - 0.0001 22.6 0.1 0.00022 21.5 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EGC34427.1 - 0.00048 20.0 0.0 0.0015 18.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC34427.1 - 0.015 14.7 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain 23S_rRNA_IVP PF05635.11 EGC34427.1 - 0.035 14.4 2.6 0.056 13.7 0.3 2.7 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein adh_short PF00106.25 EGC34427.1 - 0.08 12.4 0.1 0.16 11.4 0.1 1.5 1 0 0 1 1 1 0 short chain dehydrogenase Methyltransf_31 PF13847.6 EGC34427.1 - 0.18 11.6 0.0 0.18 11.6 0.0 3.4 4 0 0 4 4 4 0 Methyltransferase domain zf-RING_2 PF13639.6 EGC34428.1 - 5.9e-10 39.3 9.7 1.3e-09 38.3 9.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC34428.1 - 9.2e-10 38.2 6.4 1.9e-09 37.2 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC34428.1 - 2.8e-09 36.7 8.9 5e-09 35.9 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC34428.1 - 1.3e-07 31.3 9.9 1.3e-07 31.3 9.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC34428.1 - 4.5e-06 26.6 4.4 1e-05 25.5 4.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC34428.1 - 4.8e-05 23.6 6.2 0.00016 21.9 6.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC34428.1 - 0.00028 20.8 6.9 0.00028 20.8 6.9 1.9 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC34428.1 - 0.00035 20.4 5.6 0.001 18.9 5.6 1.8 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC34428.1 - 0.00084 19.5 8.7 0.0019 18.3 8.7 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC34428.1 - 0.0044 16.7 6.7 0.012 15.4 6.7 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC34428.1 - 0.012 15.4 9.9 0.029 14.2 9.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC34428.1 - 0.02 14.5 5.1 0.036 13.7 5.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EGC34428.1 - 0.042 13.7 2.5 0.086 12.7 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Pox_A21 PF05323.12 EGC34428.1 - 0.042 14.4 0.8 0.18 12.4 0.8 2.1 1 0 0 1 1 1 0 Poxvirus A21 Protein zf-ANAPC11 PF12861.7 EGC34428.1 - 0.047 13.7 2.1 0.1 12.6 2.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC34428.1 - 0.23 11.6 3.5 0.51 10.5 3.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zinc_ribbon_9 PF14369.6 EGC34428.1 - 0.94 9.8 12.4 0.061 13.6 6.5 2.0 2 0 0 2 2 2 0 zinc-ribbon PRP21_like_P PF12230.8 EGC34429.1 - 2.7e-49 168.0 17.7 2.7e-49 168.0 17.7 2.1 2 0 0 2 2 2 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.20 EGC34429.1 - 3.6e-32 110.1 5.2 2.9e-15 56.0 0.3 2.4 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.23 EGC34429.1 - 1.8e-12 46.8 0.2 4.8e-12 45.5 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family zf_UBZ PF18439.1 EGC34429.1 - 0.019 14.6 1.7 0.043 13.4 1.7 1.7 1 0 0 1 1 1 0 Ubiquitin-Binding Zinc Finger Ubiquitin_2 PF14560.6 EGC34429.1 - 0.023 15.2 0.1 0.095 13.2 0.1 2.1 1 0 0 1 1 1 0 Ubiquitin-like domain Pex14_N PF04695.13 EGC34429.1 - 0.42 11.3 37.0 2 9.1 9.5 3.5 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LSM PF01423.22 EGC34430.1 - 1.3e-18 66.5 0.6 1.6e-18 66.2 0.6 1.1 1 0 0 1 1 1 1 LSM domain Amidinotransf PF02274.17 EGC34431.1 - 9.8e-59 199.1 1.4 3e-54 184.4 1.2 2.1 2 0 0 2 2 2 2 Amidinotransferase zf-UDP PF14569.6 EGC34431.1 - 0.56 10.4 4.6 1.5 9.0 1.0 2.5 2 0 0 2 2 2 0 Zinc-binding RING-finger COX7a PF02238.15 EGC34432.1 - 3.1 8.3 10.5 7.8 7.0 0.9 3.5 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VII DUF4234 PF14018.6 EGC34432.1 - 5.1 7.3 8.1 0.99 9.6 1.4 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) Acyl_transf_3 PF01757.22 EGC34432.1 - 8.2 5.4 34.3 0.012 14.7 20.9 2.2 1 1 1 2 2 2 0 Acyltransferase family Glyco_transf_28 PF03033.20 EGC34433.1 - 2.6e-08 34.0 0.0 6.8e-08 32.6 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 N-terminal domain UDPGT PF00201.18 EGC34433.1 - 0.00093 18.1 0.0 0.0015 17.4 0.0 1.3 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.16 EGC34433.1 - 0.0012 18.8 0.0 0.0029 17.6 0.0 1.6 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain EF-hand_6 PF13405.6 EGC34434.1 - 1.9e-05 24.2 2.4 0.0029 17.4 0.5 3.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGC34434.1 - 0.00041 20.7 0.9 0.00041 20.7 0.9 3.8 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC34434.1 - 0.0068 15.9 7.1 0.011 15.3 0.6 3.6 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.6 EGC34434.1 - 0.065 13.6 0.1 2.9 8.3 0.1 3.1 3 1 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 EGC34434.1 - 2.4 8.1 7.4 2.5 8.0 0.3 3.8 4 0 0 4 4 4 0 EF-hand domain pair EF-hand_5 PF13202.6 EGC34434.1 - 6.1 6.5 7.7 0.73 9.4 1.0 3.0 3 0 0 3 3 3 0 EF hand FliJ PF02050.16 EGC34435.1 - 9.3 6.5 126.4 20 5.4 23.7 6.3 1 1 5 6 6 6 0 Flagellar FliJ protein TMEM154 PF15102.6 EGC34436.1 - 9e-08 32.1 0.0 9e-08 32.1 0.0 3.9 3 1 0 4 4 4 1 TMEM154 protein family DUF3377 PF11857.8 EGC34436.1 - 0.047 13.6 0.0 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TFIIF_alpha PF05793.12 EGC34436.1 - 0.14 10.7 25.7 0.011 14.4 20.5 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF4519 PF15012.6 EGC34436.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4519) Orf78 PF06024.12 EGC34436.1 - 1 9.7 0.0 1 9.7 0.0 3.4 2 1 0 2 2 2 0 Orf78 (ac78) Zip PF02535.22 EGC34436.1 - 6 6.0 8.7 14 4.8 8.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter FNIP PF05725.12 EGC34437.1 - 1.6e-137 447.5 93.1 2.5e-14 53.1 0.8 14.6 5 1 11 18 18 18 17 FNIP Repeat UMP1 PF05348.11 EGC34438.1 - 1.8e-18 66.9 0.0 2.2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ceramidase_alk PF04734.13 EGC34439.1 - 3e-220 732.1 0.9 3.7e-220 731.9 0.9 1.1 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase, N-terminal Ceramidse_alk_C PF17048.5 EGC34439.1 - 1.8e-50 171.1 0.3 1.8e-50 171.1 0.3 1.9 3 0 0 3 3 3 1 Neutral/alkaline non-lysosomal ceramidase, C-terminal ParBc_2 PF08857.11 EGC34440.1 - 1.2e-58 197.8 0.0 1.4e-58 197.6 0.0 1.1 1 0 0 1 1 1 1 Putative ParB-like nuclease Pesticin PF16754.5 EGC34440.1 - 0.094 12.7 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Bacterial toxin homologue of phage lysozyme, C-term TPR_17 PF13431.6 EGC34441.1 - 0.046 14.1 12.9 1.8 9.2 0.1 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat 7tm_3 PF00003.22 EGC34443.1 - 1.5e-41 142.7 15.9 2.1e-41 142.2 15.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC34443.1 - 7.3e-17 61.3 0.1 1.5e-16 60.3 0.1 1.5 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like UPF0542 PF15086.6 EGC34443.1 - 0.16 11.9 0.0 3.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 adh_short PF00106.25 EGC34444.1 - 3.1e-25 88.8 0.0 3.3e-24 85.4 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC34444.1 - 4.4e-10 39.5 0.0 2.1e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC34444.1 - 4.1e-05 23.6 0.0 6e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF4469 PF14734.6 EGC34444.1 - 0.031 14.4 1.5 0.067 13.4 1.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4469) with IG-like fold Glyco_hydro_31 PF01055.26 EGC34444.1 - 0.13 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolases family 31 7tm_3 PF00003.22 EGC34445.1 - 8.5e-39 133.7 18.4 1.3e-38 133.1 18.4 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC34445.1 - 1.3e-15 57.2 2.2 1.9e-15 56.7 2.2 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like Pox_A9 PF04835.12 EGC34445.1 - 0.13 12.5 1.8 0.41 10.8 1.8 1.9 1 0 0 1 1 1 0 A9 protein conserved region MARVEL PF01284.23 EGC34445.1 - 0.29 11.2 8.8 0.051 13.6 1.7 2.5 1 1 1 2 2 2 0 Membrane-associating domain OTU PF02338.19 EGC34446.1 - 1.6e-14 54.5 0.1 3.2e-14 53.5 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Suf PF05843.14 EGC34447.1 - 1e-93 314.6 1.8 1e-93 314.6 1.8 7.2 5 3 2 7 7 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGC34447.1 - 4.5e-11 42.6 0.0 0.0016 19.1 0.0 6.0 5 1 1 6 6 5 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC34447.1 - 1.6e-05 25.2 1.8 0.14 12.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC34447.1 - 4.2e-05 23.3 3.7 2.1 8.6 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC34447.1 - 8.2e-05 23.0 0.0 0.0015 19.0 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat HAT PF02184.16 EGC34447.1 - 8.3e-05 22.5 0.1 0.15 12.1 0.0 3.0 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_15 PF13429.6 EGC34447.1 - 0.00043 19.6 0.2 0.0097 15.1 0.0 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34447.1 - 0.0018 18.3 0.2 0.22 11.8 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGC34447.1 - 0.0091 16.0 9.6 0.84 9.6 0.1 5.5 3 2 1 4 4 4 1 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 EGC34447.1 - 0.2 12.1 7.4 0.4 11.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC34447.1 - 0.93 9.4 4.4 8.8 6.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat BSD PF03909.17 EGC34447.1 - 3.5 7.7 7.8 0.098 12.7 0.5 2.3 2 0 0 2 2 1 0 BSD domain DivIC PF04977.15 EGC34448.1 - 0.09 12.6 4.5 0.39 10.5 4.5 2.1 1 0 0 1 1 1 0 Septum formation initiator DUF4342 PF14242.6 EGC34448.1 - 0.26 11.3 1.2 1.3 9.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) TMEM154 PF15102.6 EGC34449.1 - 0.0073 16.2 1.2 0.0073 16.2 1.2 2.5 1 1 1 2 2 2 1 TMEM154 protein family ARL17 PF15840.5 EGC34449.1 - 0.1 13.0 0.0 0.19 12.1 0.0 1.4 1 0 0 1 1 1 0 ADP-ribosylation factor-like protein 17 Orf78 PF06024.12 EGC34449.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.6 2 1 0 3 3 3 0 Orf78 (ac78) RIFIN PF02009.16 EGC34449.1 - 0.18 11.7 1.2 0.22 11.4 0.6 1.3 1 1 0 1 1 1 0 Rifin ABC2_membrane_3 PF12698.7 EGC34449.1 - 0.47 9.5 8.7 0.56 9.2 8.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein zf-C3HC4_3 PF13920.6 EGC34450.1 - 6.1e-11 42.0 9.9 1.4e-10 40.9 9.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC34450.1 - 4.2e-10 39.8 10.9 9.8e-10 38.6 10.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC34450.1 - 3.2e-09 36.5 8.7 7.2e-09 35.4 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC34450.1 - 6.6e-09 35.6 8.0 1.5e-08 34.5 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGC34450.1 - 5.7e-08 32.5 10.5 1.6e-07 31.1 10.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC34450.1 - 2.6e-07 30.4 11.2 5.8e-07 29.3 11.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC34450.1 - 5.3e-07 29.6 4.5 5.3e-07 29.6 4.5 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC34450.1 - 1.1e-06 28.9 9.3 3.9e-06 27.0 9.3 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC34450.1 - 1.5e-05 25.0 8.2 1.5e-05 25.0 8.2 2.1 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC34450.1 - 1.8e-05 24.5 6.5 1.8e-05 24.5 6.5 1.8 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGC34450.1 - 0.0032 17.6 6.4 0.0066 16.6 6.4 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGC34450.1 - 0.0038 16.8 6.5 0.0038 16.8 6.5 1.8 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGC34450.1 - 0.02 14.9 7.6 0.57 10.3 7.7 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 EGC34450.1 - 0.23 11.5 6.1 0.58 10.2 6.1 1.8 1 0 0 1 1 1 0 Zinc-finger zf-RING_4 PF14570.6 EGC34450.1 - 0.4 10.5 13.7 0.73 9.7 7.4 3.1 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.14 EGC34450.1 - 0.58 9.9 10.1 19 5.0 10.4 2.5 2 1 1 3 3 3 0 P-11 zinc finger DZR PF12773.7 EGC34450.1 - 3.2 7.9 9.1 3.1 7.9 6.6 2.2 2 1 0 2 2 2 0 Double zinc ribbon p450 PF00067.22 EGC34452.1 - 1.9e-54 185.1 0.6 2.3e-54 184.9 0.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 IFN-gamma PF00714.17 EGC34452.1 - 0.047 13.5 0.6 0.24 11.3 0.1 2.3 1 1 1 2 2 2 0 Interferon gamma Pantoate_transf PF02548.15 EGC34453.1 - 3.2e-94 315.1 0.4 1.8e-91 306.1 0.0 2.4 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.11 EGC34453.1 - 1.2e-32 112.7 0.1 2.8e-32 111.5 0.1 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.16 EGC34453.1 - 1.3e-28 99.6 0.3 1.3e-28 99.6 0.3 2.1 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.23 EGC34453.1 - 0.00058 19.9 0.5 0.00058 19.9 0.5 3.8 4 0 0 4 4 4 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.14 EGC34453.1 - 0.0074 15.9 0.0 0.022 14.3 0.0 1.9 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.18 EGC34453.1 - 0.044 13.7 1.0 0.27 11.1 0.0 2.7 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain CoA_binding_2 PF13380.6 EGC34453.1 - 0.047 14.2 0.4 11 6.6 0.0 3.2 4 1 0 4 4 4 0 CoA binding domain GLE1 PF07817.13 EGC34453.1 - 1.7 7.8 5.7 3.1 6.9 5.7 1.4 1 0 0 1 1 1 0 GLE1-like protein Holin_BhlA PF10960.8 EGC34454.1 - 0.09 12.8 0.0 6.3 6.9 0.0 2.6 2 0 0 2 2 2 0 BhlA holin family Baculo_11_kDa PF06143.11 EGC34454.1 - 1.9 8.2 15.4 2.9 7.5 0.7 4.6 4 0 0 4 4 4 0 Baculovirus 11 kDa family Na_Ca_ex PF01699.24 EGC34455.1 - 1.6e-24 86.6 29.7 1.3e-14 54.4 12.3 2.0 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pex24p PF06398.11 EGC34455.1 - 0.16 10.9 0.4 11 4.8 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin PRA1 PF03208.19 EGC34455.1 - 0.65 9.6 4.2 0.31 10.7 0.2 2.5 2 1 0 2 2 2 0 PRA1 family protein Use1 PF09753.9 EGC34456.1 - 9.3e-22 77.9 26.6 6.3e-18 65.4 4.8 3.9 1 1 2 4 4 4 3 Membrane fusion protein Use1 SNARE PF05739.19 EGC34456.1 - 0.012 15.6 0.6 0.012 15.6 0.6 2.5 3 0 0 3 3 3 0 SNARE domain DUF2207 PF09972.9 EGC34456.1 - 0.3 9.8 9.7 0.029 13.1 4.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) AI-2E_transport PF01594.16 EGC34456.1 - 1.5 7.9 6.0 0.12 11.5 0.4 1.9 2 0 0 2 2 2 0 AI-2E family transporter Jnk-SapK_ap_N PF09744.9 EGC34456.1 - 2.6 8.3 24.7 0.66 10.2 2.1 2.8 3 0 0 3 3 3 0 JNK_SAPK-associated protein-1 Orf78 PF06024.12 EGC34456.1 - 4.8 7.5 14.7 0.31 11.4 0.4 3.5 4 0 0 4 4 4 0 Orf78 (ac78) SUIM_assoc PF16619.5 EGC34456.1 - 4.9 7.3 20.4 13 5.9 12.9 3.1 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Laminin_EGF PF00053.24 EGC34457.1 - 6.1e-05 23.1 21.2 0.0061 16.7 3.1 3.0 3 0 0 3 3 3 2 Laminin EGF domain EGF_2 PF07974.13 EGC34457.1 - 0.00049 20.4 22.4 0.099 13.0 12.3 3.0 2 0 0 2 2 2 2 EGF-like domain Zn-C2H2_12 PF18112.1 EGC34457.1 - 0.081 13.4 1.2 3.5 8.2 0.4 2.8 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain EB PF01683.18 EGC34457.1 - 3.1 8.2 24.6 0.25 11.6 9.3 3.4 3 0 0 3 3 3 0 EB module Hydrolase_4 PF12146.8 EGC34458.1 - 1.5e-16 60.4 0.0 2e-10 40.3 0.0 2.4 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGC34458.1 - 1e-14 54.8 0.0 2.2e-09 37.4 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EGC34458.1 - 1.6e-08 34.7 0.0 0.004 17.1 0.0 2.2 1 1 1 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_6 PF12697.7 EGC34458.1 - 1.6e-06 28.9 0.0 0.0022 18.7 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGC34458.1 - 2.4e-06 27.2 0.0 1.4e-05 24.7 0.0 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.12 EGC34458.1 - 4.6e-06 25.8 0.0 7.8e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) DLH PF01738.18 EGC34458.1 - 3.1e-05 23.6 0.0 0.0002 21.0 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_2 PF02230.16 EGC34458.1 - 0.00056 19.8 0.0 0.027 14.3 0.0 2.4 2 0 0 2 2 2 1 Phospholipase/Carboxylesterase DUF1057 PF06342.12 EGC34458.1 - 0.0019 17.3 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) AXE1 PF05448.12 EGC34458.1 - 0.0023 16.6 0.1 0.26 9.9 0.0 2.9 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) FSH1 PF03959.13 EGC34458.1 - 0.022 14.4 0.1 0.17 11.5 0.1 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF829 PF05705.14 EGC34458.1 - 0.023 14.6 0.0 0.039 13.9 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) LIDHydrolase PF10230.9 EGC34458.1 - 0.027 14.0 0.0 0.078 12.5 0.0 1.7 1 1 1 2 2 2 0 Lipid-droplet associated hydrolase UMPH-1 PF05822.12 EGC34458.1 - 0.04 13.4 0.0 0.076 12.5 0.0 1.5 2 0 0 2 2 2 0 Pyrimidine 5'-nucleotidase (UMPH-1) RasGEF PF00617.19 EGC34459.1 - 2e-51 174.7 0.5 2e-51 174.7 0.5 3.3 2 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC34459.1 - 5.3e-16 58.8 0.6 5.3e-16 58.8 0.6 5.0 5 1 0 5 5 5 1 RasGEF N-terminal motif DEP PF00610.21 EGC34459.1 - 2.7e-08 33.8 0.2 3e-07 30.4 0.0 2.4 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF962 PF06127.11 EGC34460.1 - 2e-23 82.3 0.1 4.9e-23 81.0 0.1 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.11 EGC34461.1 - 3.4e-11 43.1 0.4 9.4e-11 41.7 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF1240 PF06836.12 EGC34461.1 - 0.058 13.9 4.9 0.17 12.4 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Frizzled PF01534.17 EGC34462.1 - 5.5e-07 28.9 15.3 9.6e-07 28.1 15.3 1.4 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.24 EGC34462.1 - 0.004 16.5 11.6 0.0087 15.4 11.6 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Abhydrolase_1 PF00561.20 EGC34463.1 - 4.6e-16 59.2 0.1 7.4e-15 55.3 0.1 2.2 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34463.1 - 5.4e-08 32.4 0.0 1.1e-07 31.4 0.0 1.5 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC34463.1 - 0.00067 20.3 0.0 0.0014 19.2 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.14 EGC34463.1 - 0.011 15.3 0.0 0.016 14.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) DUF915 PF06028.11 EGC34463.1 - 0.045 13.1 0.4 0.11 11.9 0.2 1.8 2 1 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_5 PF12695.7 EGC34463.1 - 0.057 13.2 0.0 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 Alpha/beta hydrolase family Kunitz_BPTI PF00014.23 EGC34463.1 - 0.077 13.2 0.5 0.24 11.7 0.5 1.8 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain PARP PF00644.20 EGC34464.1 - 1.8e-17 63.6 4.0 5.3e-14 52.3 0.0 2.8 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain EGF_2 PF07974.13 EGC34465.1 - 0.97 9.9 13.2 2 8.9 13.2 1.5 1 0 0 1 1 1 0 EGF-like domain Glycophorin_A PF01102.18 EGC34466.1 - 0.00066 19.9 0.4 0.00074 19.7 0.4 1.2 1 0 0 1 1 1 1 Glycophorin A Podoplanin PF05808.11 EGC34466.1 - 0.0018 18.4 0.1 0.0023 18.1 0.1 1.1 1 0 0 1 1 1 1 Podoplanin Mid2 PF04478.12 EGC34466.1 - 0.024 14.5 0.6 0.027 14.3 0.6 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Syndecan PF01034.20 EGC34466.1 - 0.024 14.5 0.4 0.035 14.0 0.4 1.2 1 0 0 1 1 1 0 Syndecan domain Adeno_E3_CR2 PF02439.15 EGC34466.1 - 0.025 14.4 5.1 0.038 13.8 5.1 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 MtrF PF09472.10 EGC34466.1 - 0.041 13.3 1.0 0.065 12.6 1.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3112 PF11309.8 EGC34466.1 - 0.053 13.0 0.6 0.065 12.7 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) Amnionless PF14828.6 EGC34466.1 - 0.054 12.3 0.0 0.054 12.3 0.0 1.0 1 0 0 1 1 1 0 Amnionless TMEM154 PF15102.6 EGC34466.1 - 0.092 12.7 0.3 0.1 12.5 0.3 1.2 1 0 0 1 1 1 0 TMEM154 protein family DAP10 PF07213.11 EGC34466.1 - 0.12 12.4 0.1 0.14 12.1 0.1 1.1 1 0 0 1 1 1 0 DAP10 membrane protein EphA2_TM PF14575.6 EGC34466.1 - 0.12 13.2 1.1 0.22 12.4 1.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain BatA PF07584.11 EGC34466.1 - 0.21 12.0 0.0 0.25 11.7 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal HEAT PF02985.22 EGC34467.1 - 0.0001 22.3 1.5 0.94 9.9 0.1 4.6 4 0 0 4 4 4 2 HEAT repeat UME PF08064.13 EGC34467.1 - 0.0042 17.0 13.7 0.064 13.2 0.1 7.3 8 1 0 8 8 8 1 UME (NUC010) domain FAM176 PF14851.6 EGC34467.1 - 0.25 11.0 1.6 0.54 9.9 1.6 1.5 1 0 0 1 1 1 0 FAM176 family ABC2_membrane PF01061.24 EGC34469.1 - 2.1e-32 112.3 25.3 2.1e-32 112.3 25.3 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC34469.1 - 7.6e-29 101.0 0.1 1.4e-28 100.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC34469.1 - 4.7e-06 26.6 0.0 0.0072 16.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_18 PF13238.6 EGC34469.1 - 0.00024 21.6 0.3 0.00059 20.4 0.1 1.8 2 0 0 2 2 1 1 AAA domain AAA_29 PF13555.6 EGC34469.1 - 0.00057 19.6 0.2 0.0015 18.2 0.2 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC34469.1 - 0.0016 18.3 1.1 0.0033 17.4 1.1 1.5 1 0 0 1 1 1 1 RsgA GTPase SMC_N PF02463.19 EGC34469.1 - 0.0032 17.0 0.6 0.99 8.8 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGC34469.1 - 0.02 15.3 0.0 0.032 14.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.15 EGC34469.1 - 0.022 14.7 0.8 0.04 13.8 0.1 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_22 PF13401.6 EGC34469.1 - 0.045 14.0 0.1 0.17 12.1 0.1 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGC34469.1 - 0.054 13.1 0.0 0.091 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGC34469.1 - 0.095 12.9 0.0 0.17 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC34469.1 - 0.2 12.2 0.1 0.2 12.2 0.1 3.3 2 1 2 4 4 4 0 AAA domain Cytidylate_kin PF02224.18 EGC34469.1 - 1.3 8.8 5.8 0.24 11.1 0.2 2.4 3 0 0 3 3 3 0 Cytidylate kinase ABC2_membrane_3 PF12698.7 EGC34469.1 - 3.7 6.6 43.2 0.038 13.1 34.5 2.1 2 1 0 2 2 2 0 ABC-2 family transporter protein PDR_CDR PF06422.12 EGC34469.1 - 7.1 6.6 12.4 0.22 11.4 0.2 3.4 2 1 1 3 3 3 0 CDR ABC transporter ABC2_membrane PF01061.24 EGC34470.1 - 9.1e-35 120.0 26.9 1.9e-34 119.0 26.9 1.5 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC34470.1 - 1e-26 94.1 0.2 1e-26 94.1 0.2 2.6 2 1 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGC34470.1 - 1.5e-07 30.9 23.5 1.5e-07 30.9 23.5 2.6 2 1 1 3 3 2 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGC34470.1 - 7.8e-06 25.9 6.8 0.0043 16.9 0.2 3.2 3 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC34470.1 - 3.6e-05 23.4 0.2 8.4e-05 22.2 0.2 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC34470.1 - 0.00055 19.9 1.1 0.0018 18.2 0.9 2.0 1 1 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EGC34470.1 - 0.00073 19.2 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGC34470.1 - 0.0032 16.9 0.0 0.0032 16.9 0.0 3.0 2 2 1 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGC34470.1 - 0.0044 17.6 0.1 0.0044 17.6 0.1 2.8 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EGC34470.1 - 0.0048 17.3 0.0 0.0087 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC34470.1 - 0.0078 16.5 0.3 0.028 14.7 0.1 2.0 3 0 0 3 3 2 1 AAA domain EMP70 PF02990.16 EGC34470.1 - 0.043 12.5 16.6 0.092 11.4 16.6 1.5 1 0 0 1 1 1 0 Endomembrane protein 70 Goodbye PF17109.5 EGC34470.1 - 0.1 13.1 0.0 0.35 11.3 0.0 1.9 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain AAA_33 PF13671.6 EGC34470.1 - 0.11 12.6 0.1 0.34 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC34470.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 AAA domain ABC2_membrane_2 PF12679.7 EGC34470.1 - 0.3 10.3 12.1 0.027 13.8 6.0 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Cytidylate_kin PF02224.18 EGC34470.1 - 0.95 9.1 5.1 0.31 10.7 0.2 2.3 2 0 0 2 2 2 0 Cytidylate kinase ADP_ribosyl_GH PF03747.14 EGC34471.1 - 2.5e-50 171.9 0.0 2.9e-50 171.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Methyltransf_23 PF13489.6 EGC34472.1 - 1.1e-15 57.9 0.0 1.3e-15 57.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34472.1 - 1.5e-13 51.2 0.0 2.2e-13 50.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC34472.1 - 2.4e-12 46.9 0.0 3e-12 46.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34472.1 - 6.8e-12 45.9 0.0 1e-11 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC34472.1 - 3e-11 43.9 0.0 4.4e-11 43.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC34472.1 - 2e-07 30.2 0.0 3.1e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) PrmA PF06325.13 EGC34472.1 - 2.7e-05 23.7 0.0 3.9e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGC34472.1 - 5.8e-05 22.5 0.0 8.7e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.14 EGC34472.1 - 0.0001 21.9 0.0 0.00017 21.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain DREV PF05219.12 EGC34472.1 - 0.0011 18.1 0.0 0.011 14.9 0.0 1.9 1 1 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.18 EGC34472.1 - 0.0032 16.8 0.0 0.0044 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family AdoMet_MTase PF07757.13 EGC34472.1 - 0.038 14.3 0.5 0.078 13.3 0.2 1.7 1 1 1 2 2 2 0 Predicted AdoMet-dependent methyltransferase TehB PF03848.14 EGC34472.1 - 0.039 13.4 0.0 0.07 12.5 0.0 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB Methyltransf_18 PF12847.7 EGC34472.1 - 0.059 13.3 0.0 0.089 12.7 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Cons_hypoth95 PF03602.15 EGC34472.1 - 0.15 11.7 0.0 0.24 11.0 0.0 1.2 1 0 0 1 1 1 0 Conserved hypothetical protein 95 FtsJ PF01728.19 EGC34472.1 - 0.21 11.7 0.0 0.5 10.4 0.0 1.4 1 1 0 1 1 1 0 FtsJ-like methyltransferase zf-C3HC4_3 PF13920.6 EGC34474.1 - 0.00043 20.1 12.6 0.00043 20.1 12.6 3.5 3 0 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) CLU PF13236.6 EGC34475.1 - 6.1e-54 183.2 0.0 1.5e-53 181.9 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC34475.1 - 2.4e-05 24.5 0.8 2.4e-05 24.5 0.8 4.3 4 2 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 RabGAP-TBC PF00566.18 EGC34476.1 - 7.5e-47 159.7 10.0 7.5e-47 159.7 10.0 3.5 4 0 0 4 4 4 1 Rab-GTPase-TBC domain Pyr_redox_2 PF07992.14 EGC34477.1 - 4.3e-24 85.3 0.1 2e-11 43.6 0.0 2.5 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Rubredoxin_C PF18267.1 EGC34477.1 - 4.5e-06 26.5 0.9 1.4e-05 24.9 0.1 2.3 2 0 0 2 2 2 1 Rubredoxin NAD+ reductase C-terminal domain Pyr_redox PF00070.27 EGC34477.1 - 8.2e-05 23.1 0.1 0.35 11.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC34477.1 - 0.001 18.4 4.2 0.59 9.3 0.2 3.2 1 1 3 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGC34477.1 - 0.0095 15.1 0.1 0.017 14.3 0.1 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.6 EGC34477.1 - 0.012 15.9 0.1 0.034 14.4 0.0 1.8 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGC34477.1 - 0.058 13.0 0.0 0.19 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FAD_binding_2 PF00890.24 EGC34477.1 - 0.074 12.1 0.0 0.37 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain Ras PF00071.22 EGC34480.1 - 3.1e-59 199.2 0.1 3.9e-59 198.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34480.1 - 3e-33 114.6 0.0 5.2e-33 113.8 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34480.1 - 1.3e-12 47.6 0.0 1.7e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC34480.1 - 4e-05 23.7 0.1 0.00011 22.2 0.1 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC34480.1 - 0.00023 20.7 0.2 0.0067 16.0 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC34480.1 - 0.0015 18.5 0.2 1.7 8.5 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGC34480.1 - 0.0023 17.3 0.0 0.0036 16.7 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGC34480.1 - 0.006 16.0 0.0 0.017 14.5 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGC34480.1 - 0.014 15.1 0.1 0.07 12.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain TPR_19 PF14559.6 EGC34481.1 - 1.7e-06 28.5 0.1 3.9e-05 24.1 0.2 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC34481.1 - 1.5e-05 24.7 0.0 0.46 10.7 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34481.1 - 7.1e-05 22.7 0.2 0.66 10.3 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC34481.1 - 7.5e-05 23.0 0.0 0.018 15.3 0.0 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC34481.1 - 0.00095 18.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC34481.1 - 0.014 15.4 0.0 1 9.6 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Clathrin PF00637.20 EGC34481.1 - 0.047 13.6 4.4 0.72 9.7 0.1 3.1 2 1 1 3 3 3 0 Region in Clathrin and VPS TPR_9 PF13371.6 EGC34481.1 - 0.065 13.4 0.0 0.55 10.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC34481.1 - 0.17 12.6 0.0 0.66 10.7 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC34481.1 - 1.9 8.5 0.0 1.9 8.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Macoilin PF09726.9 EGC34481.1 - 6.3 5.2 9.1 8.8 4.7 9.1 1.1 1 0 0 1 1 1 0 Macoilin family Abhydro_lipase PF04083.16 EGC34482.1 - 4e-23 80.8 0.1 7.6e-23 79.9 0.1 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC34482.1 - 5.7e-17 62.2 0.1 3.1e-15 56.5 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34482.1 - 0.069 12.4 0.0 1.1 8.5 0.0 2.2 2 0 0 2 2 2 0 Serine aminopeptidase, S33 EMC1_C PF07774.13 EGC34483.1 - 5.8e-54 183.0 0.9 5.8e-54 183.0 0.9 2.6 3 0 0 3 3 3 1 ER membrane protein complex subunit 1, C-terminal PQQ PF01011.21 EGC34483.1 - 0.00095 19.0 0.0 2.8 8.0 0.0 4.2 4 0 0 4 4 4 2 PQQ enzyme repeat PQQ_2 PF13360.6 EGC34483.1 - 0.0072 15.9 0.0 7.5 6.1 0.0 3.3 3 0 0 3 3 3 2 PQQ-like domain DUF4987 PF16377.5 EGC34484.1 - 0.011 15.9 2.6 0.27 11.4 0.3 2.8 2 0 0 2 2 2 0 Domain of unknown function DUF4619 PF15398.6 EGC34484.1 - 0.079 12.5 5.6 0.16 11.5 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) Secretin_N_2 PF07655.13 EGC34484.1 - 1.1 9.8 12.6 0.35 11.4 1.6 3.0 3 0 0 3 3 3 0 Secretin N-terminal domain RhoGEF PF00621.20 EGC34485.1 - 4e-50 170.6 3.6 4e-50 170.6 3.6 1.9 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGC34485.1 - 2e-18 66.3 14.0 4e-18 65.3 14.0 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGC34485.1 - 2.7e-11 43.9 8.0 3.7e-11 43.5 1.4 3.3 3 0 0 3 3 3 1 PH domain IQ_SEC7_PH PF16453.5 EGC34485.1 - 4e-06 26.9 0.5 8.3e-06 25.8 0.5 1.4 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EGC34485.1 - 0.015 15.1 8.9 0.017 14.9 3.4 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain PH_3 PF14593.6 EGC34485.1 - 0.037 14.1 0.7 0.12 12.4 0.7 1.9 1 0 0 1 1 1 0 PH domain PH_16 PF17838.1 EGC34485.1 - 0.072 12.9 0.5 0.3 10.9 0.5 2.0 1 1 0 1 1 1 0 PH domain GPR15L PF15854.5 EGC34485.1 - 1.5 9.1 8.6 4 7.7 8.6 1.7 1 0 0 1 1 1 0 G-protein coupled receptor ligand 15 Med26 PF08711.11 EGC34487.1 - 2.3e-06 27.5 0.3 1.1e-05 25.3 0.3 2.3 1 0 0 1 1 1 1 TFIIS helical bundle-like domain HPS3_N PF14761.6 EGC34488.1 - 4.4e-48 163.6 3.4 1.2e-47 162.2 0.4 2.6 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3 HPS3_Mid PF14762.6 EGC34488.1 - 5.6e-31 107.7 5.0 5.6e-31 107.7 5.0 2.3 3 0 0 3 3 3 1 Hermansky-Pudlak syndrome 3, middle region HPS3_C PF14763.6 EGC34488.1 - 3.1e-05 23.5 1.7 5.4e-05 22.7 1.1 1.6 2 0 0 2 2 2 1 Hermansky-Pudlak syndrome 3, C-terminal SUIM_assoc PF16619.5 EGC34488.1 - 0.0022 18.0 4.7 0.0022 18.0 4.7 3.6 3 0 0 3 3 3 1 Unstructured region C-term to UIM in Ataxin3 Thioredoxin_8 PF13905.6 EGC34488.1 - 0.034 14.5 2.2 0.081 13.3 0.6 2.5 2 0 0 2 2 2 0 Thioredoxin-like TPR_1 PF00515.28 EGC34488.1 - 0.078 12.8 1.2 0.44 10.5 0.0 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Vps39_2 PF10367.9 EGC34488.1 - 4.7 7.7 11.8 0.28 11.6 0.1 3.5 3 0 0 3 3 3 0 Vacuolar sorting protein 39 domain 2 Pkinase PF00069.25 EGC34489.1 - 7e-46 156.7 1.1 8.2e-46 156.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34489.1 - 4.3e-27 95.0 0.3 8.5e-27 94.1 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kdo PF06293.14 EGC34489.1 - 0.0014 18.1 0.1 0.0025 17.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC34489.1 - 0.0046 16.9 0.0 0.052 13.5 0.1 1.9 1 1 1 2 2 2 2 Phosphotransferase enzyme family XRCC1_N PF01834.16 EGC34490.1 - 2.5e-40 137.9 0.3 5.5e-40 136.8 0.3 1.6 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT PF00533.26 EGC34490.1 - 4.3e-19 68.7 0.0 4.1e-11 43.1 0.0 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC34490.1 - 2.6e-13 50.2 4.5 8e-06 26.2 0.1 3.5 3 1 1 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC34490.1 - 3.6e-10 39.6 0.0 1.8e-09 37.4 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain LIG3_BRCT PF16759.5 EGC34490.1 - 3.9e-05 23.9 0.0 0.089 13.1 0.0 2.9 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain Pkinase_Tyr PF07714.17 EGC34493.1 - 5.5e-55 186.4 0.2 1e-52 179.0 0.0 3.5 3 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.25 EGC34493.1 - 6.3e-46 156.9 0.0 3.4e-45 154.5 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain PH PF00169.29 EGC34493.1 - 1.5e-15 57.5 0.4 9.5e-15 55.0 0.4 2.5 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC34493.1 - 1.3e-06 28.7 0.9 1.3e-06 28.7 0.9 4.3 4 0 0 4 4 4 1 Pleckstrin homology domain Interfer-bind PF09294.10 EGC34493.1 - 0.0013 19.1 0.1 0.0013 19.1 0.1 4.2 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Mucin PF01456.17 EGC34493.1 - 4.3 7.3 21.4 0.13 12.2 7.2 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein ATP-synt_Eps PF04627.13 EGC34494.1 - 5e-19 68.0 0.2 6.3e-19 67.7 0.2 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Misat_Tub_SegII PF10644.9 EGC34494.1 - 0.062 13.6 0.1 0.083 13.2 0.1 1.1 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Na_Ca_ex PF01699.24 EGC34495.1 - 8.5e-18 64.7 25.0 4.2e-12 46.3 12.4 2.5 2 0 0 2 2 2 2 Sodium/calcium exchanger protein CRA PF06589.11 EGC34495.1 - 3.1 7.9 9.3 0.74 9.9 0.3 3.2 3 1 0 3 3 3 0 Circumsporozoite-related antigen (CRA) CHASE6_C PF17150.4 EGC34496.1 - 0.16 12.6 0.3 0.39 11.4 0.3 1.7 1 0 0 1 1 1 0 C-terminal domain of two-partite extracellular sensor domain HSP20 PF00011.21 EGC34497.1 - 4e-18 65.4 0.4 2.4e-11 43.7 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC34497.1 - 2.2e-05 23.9 0.0 0.00018 21.0 0.0 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DHHW PF14286.6 EGC34497.1 - 0.049 13.0 5.5 0.06 12.7 5.5 1.1 1 0 0 1 1 1 0 DHHW protein CS PF04969.16 EGC34497.1 - 0.12 13.4 2.3 0.35 11.9 0.3 2.4 2 1 0 2 2 2 0 CS domain Mucin PF01456.17 EGC34497.1 - 0.25 11.3 7.4 0.32 11.0 7.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Macoilin PF09726.9 EGC34497.1 - 0.79 8.2 8.4 0.81 8.2 8.4 1.1 1 0 0 1 1 1 0 Macoilin family Thioredoxin PF00085.20 EGC34498.1 - 0.0027 17.7 0.0 0.0031 17.5 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin zf-DNL PF05180.12 EGC34498.1 - 0.16 11.9 0.6 2.8 7.9 0.1 2.2 1 1 0 2 2 2 0 DNL zinc finger DUF4834 PF16118.5 EGC34499.1 - 0.011 16.7 2.4 0.011 16.7 2.4 6.6 7 1 0 7 7 7 0 Domain of unknown function (DUF4834) SfLAP PF11139.8 EGC34499.1 - 0.015 14.8 0.0 0.69 9.3 0.0 3.1 3 1 0 3 3 3 0 Sap, sulfolipid-1-addressing protein TFB6 PF17110.5 EGC34499.1 - 0.052 13.3 0.2 0.052 13.3 0.2 4.2 5 0 0 5 5 5 0 Subunit 11 of the general transcription factor TFIIH Phosphodiest PF01663.22 EGC34499.1 - 0.16 11.6 12.6 1.9 8.0 0.0 3.0 2 1 1 3 3 3 0 Type I phosphodiesterase / nucleotide pyrophosphatase MAP17 PF15807.5 EGC34499.1 - 0.43 10.8 0.0 0.43 10.8 0.0 4.2 5 0 0 5 5 5 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF2976 PF11190.8 EGC34499.1 - 0.94 9.3 6.2 12 5.7 2.6 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) Not1 PF04054.15 EGC34500.1 - 5.6e-139 463.2 3.6 5.6e-139 463.2 3.6 4.7 5 0 0 5 5 5 1 CCR4-Not complex component, Not1 CNOT1_CAF1_bind PF16415.5 EGC34500.1 - 1.1e-84 283.3 3.9 1.1e-84 283.3 3.9 3.7 3 0 0 3 3 3 1 CCR4-NOT transcription complex subunit 1 CAF1-binding domain CNOT1_TTP_bind PF16417.5 EGC34500.1 - 2.6e-65 219.2 0.7 2.6e-65 219.2 0.7 4.9 5 0 0 5 5 5 1 CCR4-NOT transcription complex subunit 1 TTP binding domain DUF3819 PF12842.7 EGC34500.1 - 1.3e-52 177.6 0.3 1.3e-52 177.6 0.3 3.8 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) CNOT1_HEAT PF16418.5 EGC34500.1 - 4.7e-36 124.1 4.0 4.7e-36 124.1 4.0 4.4 4 0 0 4 4 4 1 CCR4-NOT transcription complex subunit 1 HEAT repeat PS_Dcarbxylase PF02666.15 EGC34501.1 - 3.9e-62 209.4 0.1 6.8e-62 208.6 0.1 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF1077 PF06417.12 EGC34501.1 - 7e-38 129.3 2.0 1.9e-37 127.8 2.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) Corazonin PF17308.2 EGC34501.1 - 0.053 13.9 7.0 0.11 12.8 7.0 1.5 1 0 0 1 1 1 0 Pro-corazonin AIF_C PF14721.6 EGC34501.1 - 0.077 13.4 3.4 0.12 12.7 2.1 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term HMG_CoA_synt_C PF08540.10 EGC34501.1 - 0.18 11.4 3.4 0.33 10.5 3.4 1.4 1 0 0 1 1 1 0 Hydroxymethylglutaryl-coenzyme A synthase C terminal DUF4271 PF14093.6 EGC34501.1 - 0.22 11.4 3.4 5.2 6.9 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4271) MFS_1 PF07690.16 EGC34502.1 - 2e-17 63.2 44.8 1.8e-11 43.6 32.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DnaB_2 PF07261.11 EGC34502.1 - 0.03 14.0 0.0 0.069 12.9 0.0 1.6 1 0 0 1 1 1 0 Replication initiation and membrane attachment Myb_DNA-binding PF00249.31 EGC34503.1 - 4.1e-20 71.7 9.5 1.4e-13 50.8 1.0 3.5 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC34503.1 - 1.9e-17 63.3 9.6 1.5e-10 41.1 0.0 3.9 1 1 2 3 3 3 3 Myb-like DNA-binding domain Ank_4 PF13637.6 EGC34503.1 - 0.015 15.9 0.0 0.061 13.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Myb_DNA-bind_4 PF13837.6 EGC34503.1 - 0.3 11.5 24.4 0.066 13.6 2.2 3.3 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Dus PF01207.17 EGC34504.1 - 3.8e-52 177.3 0.5 6.5e-52 176.5 0.2 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.15 EGC34504.1 - 0.014 14.8 0.0 0.037 13.4 0.0 1.7 1 0 0 1 1 1 0 Nitronate monooxygenase PrmA PF06325.13 EGC34504.1 - 0.039 13.3 0.2 0.039 13.3 0.2 2.6 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4634 PF15465.6 EGC34505.1 - 4.3 7.7 6.5 6.8 7.0 4.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) ODR4-like PF14778.6 EGC34506.1 - 7.1e-74 249.0 5.3 1.1e-73 248.4 5.3 1.3 1 0 0 1 1 1 1 Olfactory receptor 4-like Atg14 PF10186.9 EGC34507.1 - 6.7e-38 130.5 14.7 8.3e-38 130.2 14.7 1.1 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Sec2p PF06428.11 EGC34507.1 - 0.0025 17.7 0.6 0.0025 17.7 0.6 2.6 2 1 1 3 3 3 1 GDP/GTP exchange factor Sec2p Ureide_permease PF07168.11 EGC34507.1 - 0.053 12.3 3.4 0.085 11.6 3.4 1.3 1 0 0 1 1 1 0 Ureide permease JmjC PF02373.22 EGC34507.1 - 0.17 12.3 5.2 5.9 7.3 0.0 3.7 3 1 0 3 3 3 0 JmjC domain, hydroxylase ALMT PF11744.8 EGC34507.1 - 2.4 6.9 13.5 3.7 6.3 13.5 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter ESSS PF10183.9 EGC34508.1 - 0.023 14.9 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF3029 PF11230.8 EGC34510.1 - 0.045 12.1 0.5 0.073 11.4 0.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3029) PRKCSH_1 PF13015.6 EGC34511.1 - 0.0011 18.6 0.5 0.002 17.8 0.5 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Translin PF01997.16 EGC34512.1 - 4.6e-58 196.6 4.3 6.5e-58 196.1 4.3 1.2 1 0 0 1 1 1 1 Translin family YgaB PF14182.6 EGC34512.1 - 0.47 10.9 5.3 4 7.9 1.3 2.6 2 0 0 2 2 2 0 YgaB-like protein Fz PF01392.22 EGC34513.1 - 0.00014 22.4 2.9 0.00031 21.3 2.9 1.5 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.24 EGC34513.1 - 0.00044 19.6 12.7 0.00074 18.9 12.7 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) DPBB_1 PF03330.18 EGC34514.1 - 3.6e-06 27.2 2.6 0.00026 21.2 2.6 2.9 1 1 0 1 1 1 1 Lytic transglycolase Barwin PF00967.17 EGC34514.1 - 0.018 14.9 0.2 0.052 13.4 0.0 1.8 2 0 0 2 2 2 0 Barwin family ChpA-C PF03777.13 EGC34514.1 - 0.078 12.9 0.0 0.24 11.3 0.0 1.8 1 0 0 1 1 1 0 ChpA-C SCP2 PF02036.17 EGC34515.1 - 1.5e-50 169.8 3.7 1.2e-25 89.9 0.5 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.6 EGC34515.1 - 1.1e-11 45.1 0.4 3.1e-05 24.2 0.0 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal HMA PF00403.26 EGC34515.1 - 0.00013 22.4 1.4 6.4 7.3 0.0 4.1 4 1 0 4 4 4 2 Heavy-metal-associated domain PB1 PF00564.24 EGC34516.1 - 0.0053 16.7 0.0 0.006 16.5 0.0 1.1 1 0 0 1 1 1 1 PB1 domain RA PF00788.23 EGC34516.1 - 0.024 15.3 0.0 0.031 14.9 0.0 1.3 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain WAK_assoc PF14380.6 EGC34516.1 - 0.029 15.1 0.8 0.041 14.6 0.8 1.3 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal Hydrolase_6 PF13344.6 EGC34517.1 - 0.028 14.5 1.2 7 6.8 0.1 2.8 2 1 1 3 3 3 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.25 EGC34518.1 - 1e-73 248.0 0.0 1.8e-73 247.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34518.1 - 1.1e-46 159.3 0.0 1.9e-46 158.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC34518.1 - 8.3e-05 22.0 0.0 0.00034 20.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Pkinase_fungal PF17667.1 EGC34518.1 - 0.0015 17.4 1.0 0.0021 16.9 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase PI3K_P85_iSH2 PF16454.5 EGC34518.1 - 0.01 15.5 1.4 0.019 14.6 1.4 1.4 1 0 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain APH PF01636.23 EGC34518.1 - 0.011 15.7 0.0 0.048 13.6 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC34518.1 - 0.19 11.0 0.0 0.43 9.9 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Paz_1 PF18349.1 EGC34519.1 - 0.056 13.4 1.8 0.069 13.1 0.2 2.0 2 0 0 2 2 2 0 PAZ domain ERCC4 PF02732.15 EGC34520.1 - 4.1e-17 62.8 0.0 4.1e-17 62.8 0.0 3.4 2 1 2 4 4 4 1 ERCC4 domain AAA PF00004.29 EGC34521.1 - 1.1e-40 139.2 0.1 4.7e-40 137.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Prot_ATP_ID_OB PF16450.5 EGC34521.1 - 9.9e-16 57.4 0.2 2e-15 56.4 0.2 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_lid_3 PF17862.1 EGC34521.1 - 1.3e-12 47.3 0.1 3.4e-12 46.0 0.1 1.7 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC34521.1 - 4.3e-06 26.8 0.5 3.3e-05 23.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC34521.1 - 5.9e-06 26.8 0.1 0.0075 16.7 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.14 EGC34521.1 - 3e-05 24.2 0.0 0.00016 21.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGC34521.1 - 0.00016 21.4 0.0 0.00044 20.0 0.0 1.7 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC34521.1 - 0.00055 20.2 0.4 0.083 13.2 0.0 2.5 1 1 1 2 2 2 1 AAA domain PhoH PF02562.16 EGC34521.1 - 0.0021 17.6 0.0 0.017 14.6 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.13 EGC34521.1 - 0.003 16.8 0.0 0.0074 15.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.6 EGC34521.1 - 0.0034 17.6 0.1 0.018 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.21 EGC34521.1 - 0.0035 16.7 0.1 0.014 14.8 0.0 1.9 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.6 EGC34521.1 - 0.015 15.4 0.2 0.093 12.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGC34521.1 - 0.028 14.1 0.5 0.059 13.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_24 PF13479.6 EGC34521.1 - 0.055 13.2 0.8 0.25 11.0 0.1 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGC34521.1 - 0.056 13.8 0.0 0.17 12.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.26 EGC34521.1 - 0.06 13.0 0.0 0.33 10.7 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_7 PF12775.7 EGC34521.1 - 0.066 12.7 0.5 0.16 11.5 0.0 1.9 2 1 0 2 2 2 0 P-loop containing dynein motor region ATPase PF06745.13 EGC34521.1 - 0.074 12.4 1.4 0.18 11.1 0.0 2.3 3 0 0 3 3 3 0 KaiC SVA PF05326.11 EGC34521.1 - 0.085 12.8 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) E1-E2_ATPase PF00122.20 EGC34521.1 - 0.092 12.3 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 E1-E2 ATPase ATPase_2 PF01637.18 EGC34521.1 - 0.13 12.2 1.4 10 5.9 0.0 3.2 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_3 PF07726.11 EGC34521.1 - 0.13 12.1 0.0 0.64 9.9 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_11 PF13086.6 EGC34521.1 - 0.14 11.9 1.2 0.39 10.5 0.0 2.0 2 0 0 2 2 2 0 AAA domain Prot_ATP_OB_N PF17758.1 EGC34521.1 - 0.16 11.7 0.0 8.7 6.1 0.0 2.4 2 0 0 2 2 2 0 Proteasomal ATPase OB N-terminal domain AAA_25 PF13481.6 EGC34521.1 - 0.5 9.9 1.7 1.5 8.3 0.1 2.3 2 1 1 3 3 3 0 AAA domain ING PF12998.7 EGC34523.1 - 2.1e-25 89.3 7.8 2.1e-25 89.3 7.8 1.9 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.29 EGC34523.1 - 1.5e-06 27.9 7.7 2.8e-06 27.1 7.7 1.4 1 0 0 1 1 1 1 PHD-finger NTP_transf_4 PF13562.6 EGC34523.1 - 0.0034 17.6 1.0 0.33 11.1 1.0 2.4 2 0 0 2 2 2 1 Sugar nucleotidyl transferase RRN3 PF05327.11 EGC34523.1 - 0.033 12.8 8.9 0.042 12.4 8.9 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF4175 PF13779.6 EGC34523.1 - 0.17 9.8 5.6 0.2 9.5 5.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDHD PF02862.17 EGC34523.1 - 0.19 11.9 3.6 0.23 11.6 3.6 1.2 1 0 0 1 1 1 0 DDHD domain PRP38_assoc PF12871.7 EGC34523.1 - 0.2 12.3 3.7 0.36 11.5 3.7 1.3 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term DUF1664 PF07889.12 EGC34523.1 - 0.22 11.5 5.4 0.62 10.1 5.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4735 PF15882.5 EGC34523.1 - 0.23 10.9 8.5 0.15 11.5 6.1 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4735) zf-HC5HC2H PF13771.6 EGC34523.1 - 0.25 11.6 4.7 0.082 13.2 1.1 2.2 2 0 0 2 2 2 0 PHD-like zinc-binding domain SOGA PF11365.8 EGC34523.1 - 0.26 12.4 14.4 0.11 13.6 11.4 1.8 1 1 1 2 2 2 0 Protein SOGA Prominin PF05478.11 EGC34523.1 - 0.9 7.4 9.6 1.1 7.2 9.6 1.2 1 0 0 1 1 1 0 Prominin DNA_topoisoIV PF00521.20 EGC34523.1 - 1.1 8.1 10.8 1.5 7.6 10.8 1.2 1 0 0 1 1 1 0 DNA gyrase/topoisomerase IV, subunit A Selenoprotein_S PF06936.11 EGC34523.1 - 1.2 8.9 10.0 1.7 8.4 10.0 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4407 PF14362.6 EGC34523.1 - 3.3 7.0 7.5 4.2 6.6 7.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) YlqD PF11068.8 EGC34523.1 - 4.5 7.6 14.8 0.68 10.3 8.9 2.0 1 1 1 2 2 2 0 YlqD protein Folliculin PF11704.8 EGC34523.1 - 5.3 6.9 9.0 3.8 7.4 7.4 1.5 1 1 1 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport Presenilin PF01080.17 EGC34523.1 - 7.4 5.2 7.3 8.9 5.0 7.3 1.1 1 0 0 1 1 1 0 Presenilin V_ATPase_I PF01496.19 EGC34523.1 - 7.7 4.3 11.7 10 3.9 11.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family UCR_6-4kD PF08997.10 EGC34524.1 - 0.0014 18.5 0.1 0.0018 18.2 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.9 EGC34524.1 - 0.053 13.6 0.9 0.19 11.8 0.9 1.8 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MRP-L47 PF06984.13 EGC34525.1 - 2e-19 69.5 1.4 2.9e-19 68.9 0.3 1.8 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.23 EGC34525.1 - 2.7e-14 52.9 5.6 4.6e-14 52.1 0.5 2.8 3 0 0 3 3 3 1 Ribosomal L29 protein DUF2682 PF10909.8 EGC34525.1 - 0.044 14.3 0.3 7.8 7.1 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2682) MutL_C PF08676.11 EGC34526.1 - 6.2e-16 58.5 0.0 3.6e-15 56.0 0.0 2.4 4 0 0 4 4 4 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.6 EGC34526.1 - 5.4e-12 45.7 0.7 5.4e-12 45.7 0.7 2.9 4 0 0 4 4 4 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.19 EGC34526.1 - 7.5e-07 28.8 0.2 2.7e-06 27.0 0.2 2.1 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c PF02518.26 EGC34526.1 - 4.8e-05 23.8 1.6 7.7e-05 23.2 0.3 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase AMP-binding PF00501.28 EGC34528.1 - 1.4e-78 264.4 0.0 1.7e-78 264.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC34528.1 - 2.2e-14 54.1 0.1 5e-14 53.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PNP_UDP_1 PF01048.20 EGC34529.1 - 6.3e-31 107.4 0.5 7.4e-31 107.2 0.5 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MAGE PF01454.19 EGC34530.1 - 2.6e-30 105.7 3.8 2.6e-30 105.7 3.8 2.8 3 0 0 3 3 3 1 MAGE family baeRF_family12 PF18856.1 EGC34530.1 - 0.023 15.3 2.5 0.023 15.3 2.5 2.6 3 0 0 3 3 3 0 Bacterial archaeo-eukaryotic release factor family 12 DUF2052 PF09747.9 EGC34530.1 - 0.42 10.7 32.0 0.11 12.6 12.9 2.8 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Spt5_N PF11942.8 EGC34530.1 - 0.88 10.6 23.4 0.93 10.5 7.6 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 EGC34530.1 - 2.1 6.6 22.2 2.4 6.3 7.2 2.3 2 0 0 2 2 2 0 CDC45-like protein Prothymosin PF03247.14 EGC34530.1 - 3.1 8.3 31.3 10 6.7 14.4 2.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family PNISR PF15996.5 EGC34530.1 - 3.9 7.7 29.2 3.2 8.0 6.3 2.8 3 0 0 3 3 3 0 Arginine/serine-rich protein PNISR BSP_II PF05432.11 EGC34530.1 - 5.1 6.7 30.2 3.1 7.4 11.1 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF913 PF06025.12 EGC34530.1 - 9.4 5.1 14.0 4.1 6.3 4.4 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF913) DIOX_N PF14226.6 EGC34533.1 - 1.1e-26 93.9 0.0 1.8e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC34533.1 - 1.1e-15 57.9 0.0 1.9e-15 57.2 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COX6B PF02297.17 EGC34534.1 - 0.0015 18.7 0.3 0.0016 18.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APP_N PF02177.16 EGC34534.1 - 0.0019 18.5 0.3 0.0021 18.4 0.3 1.1 1 0 0 1 1 1 1 Amyloid A4 N-terminal heparin-binding DUF4460 PF14687.6 EGC34535.1 - 6.5e-31 106.6 1.4 6.5e-31 106.6 1.4 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.6 EGC34535.1 - 5.7e-08 32.9 0.3 2.9e-07 30.6 0.3 2.1 1 1 0 1 1 1 1 Domain of unknown function (DUF4461) Get5_C PF18514.1 EGC34535.1 - 6.9 6.5 5.5 6.1 6.6 0.3 3.2 3 0 0 3 3 3 0 Get5 C-terminal domain OST3_OST6 PF04756.13 EGC34536.1 - 2.5e-07 30.3 1.7 3.2e-07 30.0 1.7 1.0 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family PIN_2 PF10130.9 EGC34537.1 - 0.29 11.4 18.2 0.7 10.1 2.0 3.2 1 1 2 3 3 3 0 PIN domain JIP_LZII PF16471.5 EGC34537.1 - 2.1 8.6 18.9 3.1 8.0 6.8 3.6 2 1 0 3 3 3 0 JNK-interacting protein leucine zipper II EDR1 PF14381.6 EGC34537.1 - 3 7.5 7.9 0.51 10.0 3.9 1.7 1 1 1 2 2 2 0 Ethylene-responsive protein kinase Le-CTR1 DUF745 PF05335.13 EGC34537.1 - 5 6.8 15.0 0.32 10.7 5.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF745) zf_CCCH_4 PF18345.1 EGC34538.1 - 8.8e-09 35.1 17.6 0.00037 20.4 4.9 4.0 3 1 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 EGC34538.1 - 8.5e-08 31.9 14.2 0.00022 21.0 0.1 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGC34538.1 - 6.6e-05 23.1 16.2 0.0027 17.9 5.3 3.0 2 1 1 3 3 3 2 Zinc-finger containing family Torus PF16131.5 EGC34538.1 - 0.00014 22.5 27.2 0.00052 20.7 4.6 4.4 2 1 1 4 4 4 3 Torus domain zf-CCCH_4 PF18044.1 EGC34538.1 - 0.024 14.4 0.2 0.024 14.4 0.2 3.6 4 0 0 4 4 4 0 CCCH-type zinc finger zf-C3H1 PF10650.9 EGC34538.1 - 1 9.2 14.3 1.4 8.7 0.0 4.2 4 0 0 4 4 4 0 Putative zinc-finger domain E1-E2_ATPase PF00122.20 EGC34539.1 - 1.8e-29 102.6 0.2 1.8e-29 102.6 0.2 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.26 EGC34539.1 - 1e-17 65.2 0.0 8.1e-11 42.6 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 EGC34539.1 - 2.8e-15 56.5 0.1 2.8e-15 56.5 0.1 2.2 2 0 0 2 2 2 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 EGC34539.1 - 0.0013 18.4 0.0 0.0031 17.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HSP20 PF00011.21 EGC34540.1 - 3.4e-12 46.4 1.8 5.5e-12 45.7 1.8 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC34540.1 - 0.001 18.6 0.0 0.01 15.4 0.0 2.4 1 1 0 1 1 1 1 HSP20-like domain found in ArsA DUF1674 PF07896.12 EGC34541.1 - 1.2e-17 64.1 4.3 1.8e-17 63.5 4.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) KIAA1430 PF13879.6 EGC34541.1 - 0.029 15.1 2.6 0.038 14.8 2.6 1.1 1 0 0 1 1 1 0 KIAA1430 homologue BRCA2 PF00634.18 EGC34541.1 - 0.25 11.0 2.2 0.46 10.2 2.2 1.5 1 0 0 1 1 1 0 BRCA2 repeat PH PF00169.29 EGC34542.1 - 1.9e-18 66.9 0.6 1.9e-18 66.9 0.6 2.9 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EGC34542.1 - 3.2e-05 24.1 1.5 0.0004 20.6 0.1 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.6 EGC34542.1 - 0.00013 22.4 0.3 0.00013 22.4 0.3 5.0 5 0 0 5 5 5 1 Pleckstrin homology domain PH_16 PF17838.1 EGC34542.1 - 0.022 14.6 0.1 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 PH domain Glyco_hydro_38N PF01074.22 EGC34543.1 - 6.8e-77 258.7 0.5 1e-76 258.1 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGC34543.1 - 2.9e-14 53.7 0.1 1.3e-13 51.5 0.1 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGC34543.1 - 4.1e-10 39.7 0.0 8.6e-10 38.6 0.0 1.5 1 0 0 1 1 1 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGC34543.1 - 0.00046 20.2 0.4 0.0014 18.7 0.1 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Sugar_tr PF00083.24 EGC34544.1 - 2.1e-108 363.1 25.6 2.6e-108 362.8 25.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGC34544.1 - 1.8e-39 135.7 29.6 1.2e-25 90.2 7.2 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_4 PF06779.14 EGC34544.1 - 0.00033 20.1 2.0 0.00033 20.1 2.0 2.3 3 0 0 3 3 3 1 Uncharacterised MFS-type transporter YbfB Phage_holin_3_2 PF04550.12 EGC34544.1 - 0.36 11.4 3.7 0.17 12.5 0.5 2.1 2 0 0 2 2 2 0 Phage holin family 2 Myb_DNA-binding PF00249.31 EGC34545.1 - 3.2e-08 33.6 0.2 7e-08 32.6 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC34545.1 - 8.1e-06 26.0 2.7 2.9e-05 24.2 0.4 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC34545.1 - 0.00079 19.3 1.0 0.00079 19.3 1.0 3.3 3 1 0 3 3 3 1 Myb DNA-binding like DUF3984 PF13136.6 EGC34545.1 - 0.045 13.2 2.6 0.082 12.3 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) Cgr1 PF03879.14 EGC34545.1 - 3.6 8.0 15.0 1.8 9.0 1.9 3.3 2 1 1 3 3 3 0 Cgr1 family Syntaxin_2 PF14523.6 EGC34546.1 - 2.7e-09 37.3 8.0 2.7e-09 37.3 8.0 2.5 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGC34546.1 - 4.5e-07 29.8 0.1 4.5e-07 29.8 0.1 1.8 2 0 0 2 2 2 1 SNARE domain BOP1NT PF08145.12 EGC34546.1 - 0.076 12.9 4.7 0.07 13.1 1.3 2.0 2 0 0 2 2 2 0 BOP1NT (NUC169) domain DUF1190 PF06693.11 EGC34546.1 - 0.13 12.6 4.7 0.21 12.0 4.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1190) FHA PF00498.26 EGC34547.1 - 4e-12 46.3 0.5 8.1e-12 45.3 0.5 1.6 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC34547.1 - 2e-05 24.8 0.0 6.3e-05 23.2 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain CBM49 PF09478.10 EGC34548.1 - 2.7e-15 56.4 0.6 3.6e-15 56.0 0.6 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGC34549.1 - 3.3e-15 56.2 0.4 4.5e-15 55.7 0.4 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RIBIOP_C PF04950.12 EGC34550.1 - 8.1e-105 350.4 0.1 8.1e-105 350.4 0.1 1.8 2 0 0 2 2 2 1 40S ribosome biogenesis protein Tsr1 and BMS1 C-terminal AARP2CN PF08142.12 EGC34550.1 - 7.2e-20 70.9 0.1 3.6e-19 68.6 0.1 2.3 1 0 0 1 1 1 1 AARP2CN (NUC121) domain RE_MamI PF09567.10 EGC34550.1 - 0.092 12.4 5.6 0.044 13.4 0.7 2.7 2 1 0 2 2 2 0 MamI restriction endonuclease Dynamin_N PF00350.23 EGC34550.1 - 0.12 12.4 0.1 0.12 12.4 0.1 3.4 3 1 0 3 3 3 0 Dynamin family Pkinase_Tyr PF07714.17 EGC34551.1 - 1.1e-67 228.1 0.0 1.4e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC34551.1 - 3.4e-55 187.2 0.0 4.6e-55 186.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGC34551.1 - 4.6e-13 49.1 0.0 9.5e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.23 EGC34551.1 - 7.3e-05 22.8 0.5 0.00031 20.8 0.1 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family Haspin_kinase PF12330.8 EGC34551.1 - 0.00051 19.1 0.1 0.0014 17.7 0.1 1.6 2 0 0 2 2 2 1 Haspin like kinase domain Cbl_N2 PF02761.14 EGC34551.1 - 0.023 15.4 0.1 0.08 13.7 0.2 1.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, EF hand-like domain Pkinase_fungal PF17667.1 EGC34551.1 - 0.025 13.3 0.0 0.037 12.8 0.0 1.2 1 0 0 1 1 1 0 Fungal protein kinase ABC1 PF03109.16 EGC34551.1 - 0.098 12.8 0.0 1.5 9.0 0.0 2.6 2 1 0 2 2 2 0 ABC1 family Ribosomal_L37ae PF01780.19 EGC34552.1 - 0.64 10.1 5.1 2.8 8.1 0.5 2.7 3 0 0 3 3 3 0 Ribosomal L37ae protein family OrfB_Zn_ribbon PF07282.11 EGC34552.1 - 3.1 7.8 10.1 11 6.0 1.9 3.4 3 0 0 3 3 3 0 Putative transposase DNA-binding domain DUF2465 PF10239.9 EGC34553.1 - 0.059 12.6 0.1 0.19 10.9 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2465) Vps39_2 PF10367.9 EGC34554.1 - 2e-25 89.3 0.0 5.7e-25 87.9 0.0 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 CNH PF00780.22 EGC34554.1 - 2.1e-23 83.3 0.0 3.7e-23 82.5 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_1 PF10366.9 EGC34554.1 - 9.9e-22 77.3 2.8 9.9e-22 77.3 2.8 3.2 3 2 0 3 3 3 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.20 EGC34554.1 - 1.1e-14 54.5 11.4 5.8e-09 36.0 0.2 4.2 3 1 0 4 4 4 2 Region in Clathrin and VPS Flagellin_C PF00700.21 EGC34554.1 - 0.093 13.1 0.1 0.38 11.2 0.1 2.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region TPR_1 PF00515.28 EGC34554.1 - 0.14 12.1 1.4 6.8 6.7 1.1 3.2 1 1 1 2 2 2 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC34554.1 - 0.17 12.1 4.8 35 4.7 0.1 4.2 4 1 0 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 CCDC53 PF10152.9 EGC34555.1 - 0.00043 20.7 0.5 0.00051 20.5 0.5 1.1 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex Allexi_40kDa PF05549.11 EGC34555.1 - 0.00051 19.6 0.2 0.00055 19.5 0.2 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein NPV_P10 PF05531.12 EGC34555.1 - 0.0075 16.7 0.5 0.12 12.9 0.1 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein LXG PF04740.12 EGC34555.1 - 0.012 15.3 1.2 0.012 15.3 1.2 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily MbeD_MobD PF04899.12 EGC34555.1 - 0.024 14.8 0.4 0.054 13.6 0.4 1.7 1 1 0 1 1 1 0 MbeD/MobD like Phasin PF05597.11 EGC34555.1 - 0.035 14.1 0.2 0.039 14.0 0.2 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) MMR_HSR1_Xtn PF16897.5 EGC34556.1 - 1.8e-40 137.2 0.3 3.4e-40 136.3 0.3 1.5 1 0 0 1 1 1 1 C-terminal region of MMR_HSR1 domain MMR_HSR1 PF01926.23 EGC34556.1 - 1.5e-20 73.4 0.0 3.1e-20 72.3 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase TGS PF02824.21 EGC34556.1 - 1.1e-19 70.2 0.1 1.8e-19 69.5 0.1 1.3 1 0 0 1 1 1 1 TGS domain FeoB_N PF02421.18 EGC34556.1 - 7.4e-09 35.3 0.0 1.3e-08 34.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.23 EGC34556.1 - 0.00013 22.1 0.1 0.064 13.3 0.0 2.4 1 1 1 2 2 2 2 Dynamin family KTI12 PF08433.10 EGC34556.1 - 0.015 14.7 0.1 3.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AIG1 PF04548.16 EGC34556.1 - 0.078 12.3 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AAA_28 PF13521.6 EGC34556.1 - 0.089 13.0 0.2 0.25 11.6 0.2 1.7 1 0 0 1 1 1 0 AAA domain MeaB PF03308.16 EGC34556.1 - 0.099 11.6 0.4 0.31 10.0 0.1 2.0 2 1 1 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_18 PF13238.6 EGC34556.1 - 0.17 12.5 0.2 1.1 9.8 0.0 2.6 3 1 0 3 3 3 0 AAA domain DUF4188 PF13826.6 EGC34557.1 - 4.3e-05 23.8 0.1 5.3e-05 23.5 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.16 EGC34557.1 - 0.00031 20.8 0.0 0.00045 20.3 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3291 PF11695.8 EGC34557.1 - 0.04 13.6 0.3 0.084 12.6 0.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3291) Peptidase_C1 PF00112.23 EGC34558.1 - 5.6e-76 255.4 1.4 7.9e-76 255.0 1.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC34558.1 - 4.5e-13 49.4 5.8 7.5e-13 48.7 5.8 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC34558.1 - 0.00084 18.2 0.3 0.0037 16.1 0.2 1.9 2 0 0 2 2 2 1 Peptidase C1-like family VHP PF02209.19 EGC34559.1 - 6.6e-14 51.7 1.4 6.6e-14 51.7 1.4 2.9 2 0 0 2 2 2 1 Villin headpiece domain PQ-loop PF04193.14 EGC34560.1 - 1.1e-34 118.0 27.0 2.3e-18 65.7 2.7 3.6 3 1 1 4 4 4 2 PQ loop repeat Ureide_permease PF07168.11 EGC34560.1 - 0.071 11.9 4.8 0.07 11.9 1.2 2.2 2 0 0 2 2 2 0 Ureide permease PQ-loop PF04193.14 EGC34561.1 - 6.3e-35 118.8 11.4 7.4e-19 67.3 4.2 4.0 4 1 1 5 5 5 2 PQ loop repeat DUF3439 PF11921.8 EGC34562.1 - 0.029 14.4 5.3 0.058 13.4 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGC34562.1 - 0.075 11.2 6.3 0.098 10.8 6.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CENP-K PF11802.8 EGC34562.1 - 0.099 12.2 35.1 0.9 9.1 35.1 2.1 1 1 0 1 1 1 0 Centromere-associated protein K DUF1409 PF07197.12 EGC34562.1 - 0.22 11.4 1.5 14 5.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1409) Herpes_UL92 PF03048.14 EGC34562.1 - 3.1 7.5 7.3 0.79 9.5 0.2 2.7 1 1 1 3 3 3 0 UL92 family DUF2577 PF10844.8 EGC34562.1 - 6.1 7.1 9.0 0.13 12.5 1.3 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF2577) AKNA PF12443.8 EGC34562.1 - 7.3 7.3 12.7 1.7 9.3 2.2 3.3 2 1 2 4 4 4 0 AT-hook-containing transcription factor Mucin PF01456.17 EGC34562.1 - 9.7 6.2 16.3 17 5.4 16.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Secretin_N_2 PF07655.13 EGC34563.1 - 0.00034 21.1 11.3 0.00055 20.4 11.3 1.4 1 0 0 1 1 1 1 Secretin N-terminal domain Forkhead PF00250.18 EGC34563.1 - 0.0067 16.7 0.2 0.012 15.9 0.2 1.4 1 0 0 1 1 1 1 Forkhead domain Conotoxin PF02950.17 EGC34563.1 - 8.7 7.4 7.1 15 6.7 7.1 1.4 1 0 0 1 1 1 0 Conotoxin Menin PF05053.13 EGC34563.1 - 9.1 4.5 12.1 11 4.2 12.1 1.1 1 0 0 1 1 1 0 Menin Ras PF00071.22 EGC34564.1 - 1e-56 191.0 0.0 1.2e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34564.1 - 7.7e-23 81.0 0.0 1.3e-22 80.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34564.1 - 6.9e-05 22.4 0.0 9.8e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family DNA_pol3_delta2 PF13177.6 EGC34565.1 - 1.5e-13 50.8 0.0 2.3e-13 50.2 0.0 1.3 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.15 EGC34565.1 - 2.8e-06 27.4 0.1 5.7e-06 26.4 0.1 1.6 1 1 0 1 1 1 1 Rad17 P-loop domain DNA_pol3_delta PF06144.13 EGC34565.1 - 4.6e-05 23.3 0.1 0.00011 22.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_16 PF13191.6 EGC34565.1 - 0.0001 22.7 0.0 0.0099 16.3 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA PF00004.29 EGC34565.1 - 0.00014 22.3 0.1 0.0004 20.8 0.1 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Bac_DnaA PF00308.18 EGC34565.1 - 0.019 14.8 0.1 0.56 10.0 0.0 2.2 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.27 EGC34565.1 - 0.023 15.2 0.0 0.052 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter LupA PF18242.1 EGC34565.1 - 0.027 14.1 0.1 0.067 12.8 0.0 1.6 2 0 0 2 2 2 0 Legionella ubiquitin-specific protease A domain DUF815 PF05673.13 EGC34565.1 - 0.052 12.7 0.0 0.1 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) RuvB_N PF05496.12 EGC34565.1 - 0.065 13.0 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain Sigma54_activ_2 PF14532.6 EGC34565.1 - 0.065 13.4 0.0 0.45 10.6 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_24 PF13479.6 EGC34565.1 - 0.1 12.3 0.0 0.19 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_assoc_2 PF16193.5 EGC34565.1 - 0.14 12.5 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA C-terminal domain AAA_5 PF07728.14 EGC34565.1 - 0.21 11.6 0.1 1.1 9.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S21e PF01249.18 EGC34566.1 - 9.9e-36 121.7 0.0 1.1e-35 121.6 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Mre11_DNA_bind PF04152.14 EGC34567.1 - 3.9e-46 157.4 0.1 6.1e-46 156.8 0.1 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.28 EGC34567.1 - 9e-15 55.7 2.5 2.1e-14 54.5 2.5 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC34567.1 - 3.4e-06 27.4 0.0 5.8e-05 23.3 0.0 2.7 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain DUF5532 PF17673.1 EGC34567.1 - 0.14 12.2 0.0 0.33 11.0 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5532) EMP24_GP25L PF01105.24 EGC34568.1 - 4.5e-52 176.6 0.7 5.4e-52 176.4 0.7 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD SdrD_B PF17210.3 EGC34568.1 - 9.4e-05 22.6 0.0 0.00015 22.0 0.0 1.3 1 0 0 1 1 1 1 SdrD B-like domain FlgD_ig PF13860.6 EGC34568.1 - 0.0088 15.9 0.1 5.2 7.0 0.0 2.5 2 0 0 2 2 2 2 FlgD Ig-like domain Gemini_mov PF01708.16 EGC34568.1 - 0.12 12.1 0.1 0.25 11.1 0.1 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein PHD PF00628.29 EGC34569.1 - 5.3e-16 58.2 27.6 4.1e-09 36.2 11.3 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.6 EGC34569.1 - 0.0013 18.2 14.4 0.0017 17.8 5.5 2.4 2 0 0 2 2 2 2 PHD-finger zf-CW PF07496.15 EGC34569.1 - 0.0051 16.8 23.1 0.043 13.9 7.9 3.1 3 0 0 3 3 3 2 CW-type Zinc Finger HCO3_cotransp PF00955.21 EGC34570.1 - 3.7e-120 402.2 29.0 1.2e-68 232.3 9.2 2.8 1 1 2 3 3 3 2 HCO3- transporter family Suc_Fer-like PF06999.12 EGC34571.1 - 5.9e-41 140.5 0.0 8.9e-41 139.9 0.0 1.3 1 0 0 1 1 1 1 Sucrase/ferredoxin-like Mucin PF01456.17 EGC34571.1 - 0.0035 17.3 9.4 0.0058 16.6 9.4 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Fer2_2 PF01799.20 EGC34571.1 - 0.034 14.2 0.1 9.5 6.3 0.0 2.6 2 0 0 2 2 2 0 [2Fe-2S] binding domain Metallophos_2 PF12850.7 EGC34571.1 - 0.036 14.3 0.0 0.057 13.6 0.0 1.2 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SSP160 PF06933.11 EGC34571.1 - 0.059 11.6 9.3 0.076 11.2 9.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 zf-BED PF02892.15 EGC34571.1 - 0.68 10.0 3.0 27 4.9 0.4 2.8 3 0 0 3 3 3 0 BED zinc finger DUF3439 PF11921.8 EGC34571.1 - 1.5 8.8 9.2 3.3 7.7 8.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) IF4E PF01652.18 EGC34572.1 - 8.7e-36 123.1 0.9 8.7e-36 123.1 0.9 2.9 3 0 0 3 3 3 1 Eukaryotic initiation factor 4E SARAF PF06682.12 EGC34573.1 - 0.015 15.0 0.1 0.02 14.6 0.1 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis SSP160 PF06933.11 EGC34573.1 - 0.028 12.7 3.0 0.034 12.4 3.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DHR-2 PF06920.13 EGC34574.1 - 1.1e-102 344.5 17.1 1.1e-102 344.5 17.1 2.9 3 1 0 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 EGC34574.1 - 1.5e-25 90.2 5.7 1.5e-25 90.2 5.7 2.9 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins C2 PF00168.30 EGC34574.1 - 0.0086 16.4 0.0 0.03 14.6 0.0 1.9 1 0 0 1 1 1 1 C2 domain Glyco_transf_10 PF00852.19 EGC34574.1 - 0.011 15.4 0.2 0.048 13.4 0.2 2.1 1 0 0 1 1 1 0 Glycosyltransferase family 10 (fucosyltransferase) C-term IMP_cyclohyd PF07826.11 EGC34574.1 - 0.073 12.7 0.0 0.2 11.2 0.0 1.7 1 0 0 1 1 1 0 IMP cyclohydrolase-like protein Methyltransf_FA PF12248.8 EGC34574.1 - 0.11 12.9 1.5 0.71 10.2 0.1 2.9 2 0 0 2 2 2 0 Farnesoic acid 0-methyl transferase gerPA PF10676.9 EGC34574.1 - 0.12 12.7 0.0 0.12 12.7 0.0 4.7 4 2 2 6 6 6 0 Spore germination protein gerPA/gerPF Sec16_C PF12931.7 EGC34575.1 - 3.7e-50 171.3 0.1 9.6e-50 169.9 0.1 1.7 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.7 EGC34575.1 - 1.3e-19 70.9 1.5 7.5e-19 68.5 0.0 3.3 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region CAF-1_p150 PF11600.8 EGC34575.1 - 0.34 10.6 25.5 0.9 9.2 25.5 1.6 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DNA_topoisoIV PF00521.20 EGC34576.1 - 1e-110 370.6 10.3 2e-109 366.3 10.3 2.2 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGC34576.1 - 5e-46 156.1 1.8 5e-46 156.1 1.8 3.2 3 0 0 3 3 3 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGC34576.1 - 1.2e-21 77.0 0.2 4.9e-21 75.0 0.2 2.1 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGC34576.1 - 3e-12 47.0 0.2 3.8e-11 43.5 0.0 2.5 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGC34576.1 - 2.9e-06 27.4 0.0 1.5e-05 25.1 0.0 2.3 1 0 0 1 1 1 1 Toprim domain DUF1018 PF06252.12 EGC34576.1 - 0.049 14.6 0.9 0.13 13.3 0.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1018) Dicty_CTDC PF00526.18 EGC34577.1 - 6.9e-285 917.9 676.5 4.5e-12 45.6 14.7 33.1 33 1 0 33 33 33 32 Dictyostelium (slime mold) repeat ATP_bind_3 PF01171.20 EGC34579.1 - 9.6e-33 113.5 0.0 2.2e-32 112.3 0.0 1.6 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.17 EGC34579.1 - 0.047 12.8 0.1 0.15 11.2 0.1 1.9 1 1 0 1 1 1 0 NAD synthase DUF3800 PF12686.7 EGC34579.1 - 0.37 11.4 2.5 39 4.9 2.5 3.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3800) EVI2A PF05399.11 EGC34579.1 - 2 7.9 5.9 3.5 7.1 5.9 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Cation_ATPase_C PF00689.21 EGC34580.1 - 0.048 13.4 5.7 0.1 12.3 4.0 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF5446 PF17522.2 EGC34580.1 - 0.12 12.6 1.2 2.9 8.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5446) Doppel PF11466.8 EGC34580.1 - 0.16 11.7 0.2 0.16 11.7 0.2 1.7 2 0 0 2 2 2 0 Prion-like protein Doppel DUF2207 PF09972.9 EGC34580.1 - 0.9 8.2 11.5 0.46 9.2 9.8 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) OppC_N PF12911.7 EGC34580.1 - 0.9 9.6 4.4 10 6.2 3.4 2.7 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Mitofilin PF09731.9 EGC34581.1 - 8e-40 137.3 51.1 8e-40 137.3 51.1 3.0 1 1 1 2 2 2 1 Mitochondrial inner membrane protein AD PF09793.9 EGC34582.1 - 3.6e-26 91.1 0.1 5.1e-26 90.6 0.1 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.12 EGC34582.1 - 0.00063 19.3 0.2 0.082 12.4 0.0 2.3 2 0 0 2 2 2 2 Gemin6 protein adh_short PF00106.25 EGC34583.1 - 6.4e-35 120.4 0.0 8.3e-35 120.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC34583.1 - 3.2e-15 56.3 0.0 4e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC34583.1 - 3.7e-08 33.5 0.0 5.2e-08 33.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC34583.1 - 0.00049 19.3 0.0 0.0007 18.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGC34583.1 - 0.14 11.6 0.0 0.31 10.5 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Saf_2TM PF18303.1 EGC34583.1 - 0.2 11.2 2.0 0.98 9.0 1.0 2.3 2 0 0 2 2 2 0 SAVED-fused 2TM effector domain Arf PF00025.21 EGC34585.1 - 4.3e-64 215.2 0.1 5.1e-64 214.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC34585.1 - 3.9e-14 52.9 0.0 5.3e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC34585.1 - 1.8e-13 50.4 0.0 2e-13 50.3 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC34585.1 - 5.6e-11 42.2 0.0 6.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC34585.1 - 2.1e-09 37.0 1.7 2e-06 27.2 0.3 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC34585.1 - 2.2e-07 30.5 0.0 2.6e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC34585.1 - 7.5e-05 22.8 0.0 0.00011 22.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGC34585.1 - 0.014 15.9 0.1 0.023 15.2 0.1 1.4 1 1 0 1 1 1 0 ABC transporter DUF4003 PF13170.6 EGC34585.1 - 0.057 12.8 0.0 0.07 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4003) SRP54 PF00448.22 EGC34585.1 - 0.12 12.0 0.0 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MeaB PF03308.16 EGC34585.1 - 0.16 10.9 0.0 4.1 6.3 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB KxDL PF10241.9 EGC34589.1 - 0.03 14.6 2.8 0.047 14.0 0.6 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein CHD5 PF04420.14 EGC34589.1 - 0.038 13.9 0.5 0.066 13.1 0.1 1.8 2 0 0 2 2 2 0 CHD5-like protein Mating_N PF12731.7 EGC34589.1 - 0.042 13.9 0.9 2 8.6 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF4795 PF16043.5 EGC34589.1 - 0.056 13.1 3.5 0.66 9.6 0.4 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4795) Phage_Mu_Gam PF07352.12 EGC34589.1 - 0.095 12.6 5.2 1 9.2 1.0 2.3 2 0 0 2 2 2 0 Bacteriophage Mu Gam like protein SurA_N_2 PF13623.6 EGC34589.1 - 0.11 12.4 1.4 1.9 8.3 0.1 2.8 3 0 0 3 3 3 0 SurA N-terminal domain EGF_2 PF07974.13 EGC34590.1 - 1.3e-06 28.7 45.7 0.0048 17.2 12.8 4.0 3 0 0 3 3 3 3 EGF-like domain EGF_Tenascin PF18720.1 EGC34590.1 - 0.005 16.9 8.1 0.005 16.9 8.1 3.6 3 0 0 3 3 3 1 Tenascin EGF domain Laminin_EGF PF00053.24 EGC34590.1 - 0.012 15.7 4.1 0.012 15.7 4.1 4.0 3 0 0 3 3 3 0 Laminin EGF domain HSP20 PF00011.21 EGC34591.1 - 4.4e-13 49.3 2.4 4.2e-06 26.9 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC34591.1 - 0.0034 16.9 0.1 0.053 13.1 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Pro_isomerase PF00160.21 EGC34592.1 - 9.4e-50 169.0 0.4 1.1e-49 168.8 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SnoaL_2 PF12680.7 EGC34593.1 - 1.8e-05 25.3 0.0 2.1e-05 25.1 0.0 1.0 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC34593.1 - 0.00075 19.3 0.3 0.0021 17.8 0.3 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.6 EGC34593.1 - 0.015 15.7 0.0 0.018 15.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) DUF3271 PF11675.8 EGC34593.1 - 0.021 14.1 0.8 0.021 14.1 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) RRM_1 PF00076.22 EGC34594.1 - 1.3e-19 69.7 1.0 2.5e-09 36.8 0.6 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.15 EGC34594.1 - 1.8e-07 31.0 3.9 1.8e-05 24.7 0.7 2.7 3 0 0 3 3 3 2 DbpA RNA binding domain RRM_5 PF13893.6 EGC34594.1 - 2.7e-05 23.8 1.9 0.014 15.0 0.1 2.3 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC34594.1 - 0.0036 17.1 0.4 3.9 7.4 0.1 2.4 2 0 0 2 2 2 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGC34594.1 - 0.016 15.3 0.2 0.23 11.6 0.2 2.6 1 1 0 1 1 1 0 RNA recognition motif RRM_5 PF13893.6 EGC34595.1 - 1.8e-37 127.7 3.0 6e-27 93.7 0.2 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGC34595.1 - 1.3e-17 63.4 0.0 0.00018 21.3 0.0 5.1 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RL PF17797.1 EGC34595.1 - 0.069 13.1 0.5 0.6 10.1 0.0 2.8 3 0 0 3 3 3 0 RL domain DUF4387 PF14330.6 EGC34595.1 - 0.15 12.7 0.8 2.3 8.9 0.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4387) UCH PF00443.29 EGC34596.1 - 4.1e-46 157.6 3.0 4.1e-46 157.6 3.0 5.5 6 2 0 6 6 6 2 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC34596.1 - 1.1e-32 113.9 1.9 1.1e-32 113.9 1.9 4.2 3 3 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGC34596.1 - 4.1e-06 26.5 0.6 2.3e-05 24.0 0.6 2.4 1 0 0 1 1 1 1 Ubiquitin family Cbl_N2 PF02761.14 EGC34597.1 - 0.19 12.5 0.4 0.19 12.5 0.4 2.2 3 0 0 3 3 3 0 CBL proto-oncogene N-terminus, EF hand-like domain Transferase PF02458.15 EGC34598.1 - 3.2e-08 32.7 0.0 5.8e-08 31.8 0.0 1.4 1 1 0 1 1 1 1 Transferase family Clat_adaptor_s PF01217.20 EGC34599.1 - 1.1e-45 155.1 4.2 1.5e-45 154.7 4.2 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.6 EGC34599.1 - 0.0093 16.0 0.1 0.015 15.3 0.1 1.4 1 1 0 1 1 1 1 AP-5 complex subunit sigma-1 Methyltransf_31 PF13847.6 EGC34600.1 - 2.5e-11 43.6 0.0 3e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34600.1 - 2.2e-10 41.1 0.0 3.9e-10 40.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34600.1 - 1.1e-07 32.4 0.0 1.9e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGC34600.1 - 5.8e-06 25.8 0.0 7.9e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGC34600.1 - 9.1e-06 25.3 0.1 1.3e-05 24.8 0.1 1.3 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EGC34600.1 - 1.3e-05 25.9 0.0 1.8e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC34600.1 - 2.3e-05 24.0 0.0 3.6e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain N6_N4_Mtase PF01555.18 EGC34600.1 - 4.2e-05 23.4 0.1 6.8e-05 22.7 0.1 1.3 1 0 0 1 1 1 1 DNA methylase Methyltransf_23 PF13489.6 EGC34600.1 - 7.5e-05 22.6 0.0 8.7e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC34600.1 - 0.0002 21.3 0.1 0.00032 20.6 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGC34600.1 - 0.00023 20.8 0.0 0.00034 20.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 UPF0020 PF01170.18 EGC34600.1 - 0.00032 20.4 0.1 0.013 15.2 0.1 2.1 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 TehB PF03848.14 EGC34600.1 - 0.00049 19.6 0.1 0.00088 18.7 0.1 1.4 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.10 EGC34600.1 - 0.00097 18.7 0.0 0.0015 18.2 0.0 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.6 EGC34600.1 - 0.0023 18.0 0.0 0.0028 17.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC34600.1 - 0.0051 16.2 0.1 0.007 15.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.12 EGC34600.1 - 0.0053 16.4 0.0 0.0081 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Met_10 PF02475.16 EGC34600.1 - 0.0063 16.3 0.0 0.0089 15.8 0.0 1.2 1 0 0 1 1 1 1 Met-10+ like-protein ADH_zinc_N PF00107.26 EGC34600.1 - 0.009 16.0 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 EGC34600.1 - 0.016 14.7 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase PCMT PF01135.19 EGC34600.1 - 0.061 13.1 0.0 0.089 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.15 EGC34600.1 - 0.1 12.5 0.2 0.17 11.7 0.1 1.4 2 0 0 2 2 2 0 Hypothetical methyltransferase Profilin PF00235.19 EGC34601.1 - 9.8e-10 38.8 0.5 1.1e-09 38.6 0.5 1.0 1 0 0 1 1 1 1 Profilin HSP20 PF00011.21 EGC34602.1 - 5.2e-16 58.7 0.6 1.3e-15 57.4 0.6 1.6 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC34602.1 - 0.00055 19.4 0.1 0.0012 18.4 0.1 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EGC34602.1 - 0.032 15.2 1.2 0.083 13.9 1.2 1.9 1 1 0 1 1 1 0 CS domain DUF4974 PF16344.5 EGC34602.1 - 0.061 13.3 0.1 0.061 13.3 0.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4974) TLD PF07534.16 EGC34603.1 - 1.9e-36 125.3 0.7 1.9e-36 125.3 0.7 6.0 5 2 1 7 7 7 1 TLD HemN_C PF06969.16 EGC34603.1 - 7.8e-07 29.1 1.4 1.3e-06 28.3 0.5 1.9 2 0 0 2 2 2 1 HemN C-terminal domain Radical_SAM PF04055.21 EGC34603.1 - 1.5e-05 25.4 0.0 3.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily LysM PF01476.20 EGC34603.1 - 4e-05 23.6 0.2 0.00017 21.6 0.2 2.1 1 0 0 1 1 1 1 LysM domain SARAF PF06682.12 EGC34603.1 - 4.2 6.9 14.3 1.1 8.8 2.8 3.0 3 0 0 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Methyltransf_11 PF08241.12 EGC34604.1 - 6.9e-23 81.1 0.0 1.8e-22 79.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34604.1 - 4.5e-20 72.2 0.0 9.7e-20 71.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC34604.1 - 2.1e-19 69.8 0.0 3.8e-19 69.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34604.1 - 5.4e-19 68.6 0.0 8.2e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC34604.1 - 1.3e-16 60.7 0.0 4.1e-16 59.0 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGC34604.1 - 2.4e-12 47.4 0.0 5.1e-11 43.2 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain CMAS PF02353.20 EGC34604.1 - 2.6e-11 43.3 0.0 4.4e-11 42.6 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.12 EGC34604.1 - 7.2e-05 22.5 0.0 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Polyketide_cyc2 PF10604.9 EGC34604.1 - 0.00026 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Methyltransf_15 PF09445.10 EGC34604.1 - 0.00092 18.8 0.0 0.002 17.7 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.15 EGC34604.1 - 0.00099 19.0 0.0 0.042 13.7 0.0 2.6 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.16 EGC34604.1 - 0.0013 17.4 0.0 0.0025 16.4 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase COXG PF06240.13 EGC34604.1 - 0.0015 18.3 0.3 0.003 17.3 0.3 1.5 1 1 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Methyltransf_2 PF00891.18 EGC34604.1 - 0.0041 16.4 0.0 0.0066 15.8 0.0 1.3 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_32 PF13679.6 EGC34604.1 - 0.01 15.8 0.0 0.019 15.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain DOT1 PF08123.13 EGC34604.1 - 0.012 15.1 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 PCMT PF01135.19 EGC34604.1 - 0.051 13.3 0.0 0.094 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGC34604.1 - 0.054 13.0 0.0 0.11 12.0 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain UPF0020 PF01170.18 EGC34604.1 - 0.07 12.8 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 zf-met2 PF12907.7 EGC34606.1 - 1.8e-17 63.2 4.1 2.4e-17 62.8 4.1 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.14 EGC34606.1 - 5.3e-08 33.6 10.6 9.5e-08 32.8 10.6 1.4 1 0 0 1 1 1 1 4F5 protein family Rpr2 PF04032.16 EGC34606.1 - 0.0095 16.2 1.5 0.011 16.0 1.5 1.2 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-C2H2_12 PF18658.1 EGC34606.1 - 0.022 14.3 0.1 0.031 13.8 0.1 1.2 1 0 0 1 1 1 0 Zinc-finger C2H2-type DUF726 PF05277.12 EGC34607.1 - 1.2e-67 228.3 13.5 9e-67 225.4 1.4 2.6 3 0 0 3 3 3 2 Protein of unknown function (DUF726) VPS9 PF02204.18 EGC34607.1 - 6.7e-26 90.5 0.0 2.4e-25 88.7 0.0 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DPBB_1 PF03330.18 EGC34608.1 - 6.4e-10 39.2 0.5 7.4e-09 35.8 0.4 2.5 2 1 0 2 2 2 1 Lytic transglycolase Barwin PF00967.17 EGC34608.1 - 0.0048 16.7 0.1 0.0093 15.8 0.1 1.5 1 0 0 1 1 1 1 Barwin family Pollen_allerg_1 PF01357.21 EGC34608.1 - 0.014 15.4 0.1 0.03 14.4 0.1 1.5 1 0 0 1 1 1 0 Pollen allergen Cerato-platanin PF07249.12 EGC34608.1 - 0.025 14.7 0.1 0.056 13.6 0.1 1.6 1 0 0 1 1 1 0 Cerato-platanin CPSase_L_D2 PF02786.17 EGC34609.1 - 1.4e-72 243.6 0.2 2.5e-72 242.8 0.2 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGC34609.1 - 5.3e-45 152.5 0.2 1.2e-44 151.4 0.2 1.6 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGC34609.1 - 5.5e-39 132.6 0.0 1.4e-38 131.3 0.0 1.8 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGC34609.1 - 9.2e-18 63.8 0.6 2.5e-16 59.2 0.4 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGC34609.1 - 1.8e-09 37.5 0.0 4.4e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGC34609.1 - 6.9e-08 32.2 0.2 1.8e-07 30.9 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain PCC_BT PF18140.1 EGC34609.1 - 1.5e-07 31.8 0.0 3.9e-07 30.5 0.0 1.8 1 0 0 1 1 1 1 Propionyl-coenzyme A carboxylase BT domain ATP-grasp_3 PF02655.14 EGC34609.1 - 4.8e-07 30.0 0.1 4.3e-06 26.9 0.1 2.4 3 0 0 3 3 3 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGC34609.1 - 0.00033 20.0 0.2 0.0029 16.9 0.1 2.4 3 0 0 3 3 3 1 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.6 EGC34609.1 - 0.0031 18.2 0.1 0.089 13.5 0.0 2.8 2 0 0 2 2 2 1 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EGC34609.1 - 0.022 14.6 0.1 2 8.3 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like ATP-grasp_5 PF13549.6 EGC34609.1 - 0.093 12.2 0.0 0.26 10.7 0.0 1.7 1 0 0 1 1 1 0 ATP-grasp domain SNARE_assoc PF09335.11 EGC34610.1 - 4.4e-30 104.6 5.2 4.4e-30 104.6 5.2 2.1 3 1 0 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.11 EGC34610.1 - 2.1e-05 24.9 0.4 0.0013 19.1 0.0 2.4 1 1 0 2 2 2 1 Domain of unknown function (DUF1772) NfeD PF01957.18 EGC34610.1 - 0.045 14.1 1.2 4.8 7.6 0.0 2.9 3 0 0 3 3 3 0 NfeD-like C-terminal, partner-binding Phage_holin_6_1 PF09682.10 EGC34610.1 - 0.22 11.9 6.5 8.3 6.9 0.1 3.3 3 0 0 3 3 3 0 Bacteriophage holin of superfamily 6 (Holin_LLH) UPF0154 PF03672.13 EGC34610.1 - 0.45 10.6 0.1 0.45 10.6 0.1 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) RseC_MucC PF04246.12 EGC34610.1 - 1.1 9.2 8.9 2 8.4 3.1 2.7 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC PUF PF00806.19 EGC34611.1 - 2.4e-38 127.7 24.0 3.7e-06 26.3 0.3 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat CPL PF08144.11 EGC34611.1 - 4.4e-06 27.1 3.0 0.23 11.8 1.0 4.2 1 1 3 4 4 4 3 CPL (NUC119) domain HU-CCDC81_euk_1 PF14908.6 EGC34611.1 - 0.012 15.7 0.1 0.81 9.9 0.1 3.1 2 0 0 2 2 2 0 CCDC81 eukaryotic HU domain 1 Glyoxalase_2 PF12681.7 EGC34611.1 - 0.56 10.1 4.5 0.87 9.5 0.1 2.7 3 0 0 3 3 3 0 Glyoxalase-like domain G-patch PF01585.23 EGC34612.1 - 3.4e-11 42.8 1.1 7.8e-11 41.7 1.1 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.7 EGC34612.1 - 2.9e-06 27.3 0.4 2.9e-06 27.3 0.4 3.8 4 1 0 4 4 4 1 G-patch domain LAP1C PF05609.12 EGC34612.1 - 1.7 7.7 40.8 2.5 7.1 40.8 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) PAP1 PF08601.10 EGC34612.1 - 3.7 7.2 48.4 5.2 6.7 48.4 1.4 1 0 0 1 1 1 0 Transcription factor PAP1 DUF936 PF06075.12 EGC34612.1 - 5.3 5.8 52.8 6.5 5.6 52.8 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) ADH_N PF08240.12 EGC34614.1 - 5.7e-24 84.1 2.9 1.1e-23 83.1 2.9 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC34614.1 - 2.4e-20 72.9 0.1 4.1e-20 72.1 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC34614.1 - 0.0035 18.4 0.0 0.0067 17.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGC34614.1 - 0.006 16.0 0.1 0.0095 15.3 0.1 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.18 EGC34614.1 - 0.021 15.1 0.1 0.033 14.4 0.1 1.3 1 0 0 1 1 1 0 TrkA-N domain UDPG_MGDP_dh_N PF03721.14 EGC34614.1 - 0.043 13.4 0.2 0.077 12.6 0.2 1.4 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ADH_N_2 PF16884.5 EGC34614.1 - 0.088 12.7 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase FYVE PF01363.21 EGC34615.1 - 1.2e-20 73.4 5.9 2.3e-20 72.5 5.9 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pkinase_Tyr PF07714.17 EGC34615.1 - 5.6e-11 42.2 1.4 1.5e-10 40.8 1.4 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC34615.1 - 8.8e-09 35.1 1.5 3.6e-08 33.1 1.5 1.9 1 1 0 1 1 1 1 Protein kinase domain zf_C2HC_14 PF18574.1 EGC34615.1 - 0.077 12.8 4.6 0.19 11.5 4.6 1.6 1 0 0 1 1 1 0 C2HC Zing finger domain FYVE_2 PF02318.16 EGC34615.1 - 0.24 11.6 5.5 0.45 10.7 5.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger WH2 PF02205.20 EGC34615.1 - 3 7.8 5.1 1.2 9.1 0.2 2.7 2 1 0 2 2 2 0 WH2 motif SOG2 PF10428.9 EGC34615.1 - 4.4 6.4 16.5 7.7 5.6 16.5 1.3 1 0 0 1 1 1 0 RAM signalling pathway protein HypA PF01155.19 EGC34615.1 - 7.2 6.7 5.9 6.6 6.8 2.5 2.2 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA CAP_N PF01213.19 EGC34615.1 - 9.5 5.6 18.6 12 5.3 17.3 1.8 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal BORCS7 PF16088.5 EGC34616.1 - 5e-29 100.6 6.9 6.1e-29 100.3 6.9 1.1 1 0 0 1 1 1 1 BLOC-1-related complex sub-unit 7 Lipoprotein_7 PF01540.16 EGC34616.1 - 0.00013 21.4 1.4 0.00015 21.2 1.4 1.0 1 0 0 1 1 1 1 Adhesin lipoprotein DegS PF05384.11 EGC34616.1 - 0.035 13.6 0.9 1.7 8.1 0.0 2.1 1 1 1 2 2 2 0 Sensor protein DegS HTH_41 PF14502.6 EGC34616.1 - 0.11 12.2 0.1 0.19 11.4 0.1 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain CLU PF13236.6 EGC34617.1 - 3.4e-87 291.9 1.4 4.2e-87 291.6 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC34617.1 - 1.3e-48 165.4 0.1 1.3e-48 165.4 0.1 4.5 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.6 EGC34617.1 - 5.5e-34 116.3 0.4 7.6e-10 38.9 0.1 3.7 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.6 EGC34617.1 - 6.8e-15 54.4 0.0 0.019 14.8 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat CLU_N PF15044.6 EGC34617.1 - 9.2e-12 45.2 1.4 3.5e-11 43.3 0.0 2.9 3 0 0 3 3 2 1 Mitochondrial function, CLU-N-term DUF727 PF05303.12 EGC34617.1 - 2.8e-07 30.6 0.3 1.4e-06 28.3 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF727) TPR_2 PF07719.17 EGC34617.1 - 3e-06 26.9 0.1 23 5.4 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC34617.1 - 3.2e-06 26.7 2.8 4.9 7.1 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC34617.1 - 6.4e-05 22.7 0.4 1 9.5 0.0 4.7 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34617.1 - 0.0014 18.7 0.9 9.1 6.8 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_MalT PF17874.1 EGC34617.1 - 0.0082 15.5 0.0 0.027 13.8 0.0 1.8 1 1 0 1 1 1 1 MalT-like TPR region DUF5113 PF17140.4 EGC34617.1 - 0.028 14.2 0.2 0.17 11.7 0.1 2.4 2 1 1 3 3 3 0 Domain of unknown function (DUF5113) DLIC PF05783.11 EGC34618.1 - 5.3e-94 315.7 11.4 2.2e-63 214.7 1.8 2.0 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) Roc PF08477.13 EGC34618.1 - 0.0096 16.1 1.5 0.015 15.5 0.0 2.1 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase DUF3408 PF11888.8 EGC34618.1 - 0.017 15.3 2.8 0.15 12.2 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) UPF0061 PF02696.14 EGC34618.1 - 0.22 10.2 2.5 0.42 9.3 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, YdiU/UPF0061 family Tristanin_u2 PF16638.5 EGC34618.1 - 1 10.2 4.7 16 6.4 0.3 2.5 2 0 0 2 2 2 0 Unstructured region on methyltransferase between zinc-fingers Hamartin PF04388.12 EGC34618.1 - 1.4 7.5 16.3 4.9 5.7 10.5 2.1 2 0 0 2 2 2 0 Hamartin protein Glyco_hydro_3 PF00933.21 EGC34619.1 - 5.3e-61 206.7 0.0 7e-61 206.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.22 EGC34619.1 - 2.4e-48 164.8 0.0 4.7e-48 163.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.6 EGC34619.1 - 3.4e-15 55.9 0.0 7.2e-15 54.9 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.18 EGC34619.1 - 0.0029 17.8 1.0 0.011 16.1 0.2 2.3 2 0 0 2 2 2 1 Domain of unknown function DUF11 CARDB PF07705.11 EGC34619.1 - 0.062 13.6 0.0 0.17 12.2 0.0 1.7 1 0 0 1 1 1 0 CARDB FNIP PF05725.12 EGC34620.1 - 1.3e-84 278.1 86.5 2e-14 53.4 0.6 12.9 6 2 9 16 16 16 16 FNIP Repeat LRR_5 PF13306.6 EGC34620.1 - 0.00037 20.4 26.0 0.069 13.1 7.3 5.0 3 2 0 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF928 PF06051.12 EGC34620.1 - 0.044 13.6 0.1 12 5.7 0.0 2.8 2 1 1 3 3 3 0 Domain of Unknown Function (DUF928) LRR_8 PF13855.6 EGC34620.1 - 0.12 12.2 9.9 1.1 9.1 0.0 5.4 4 1 0 5 5 5 0 Leucine rich repeat EGF_CA PF07645.15 EGC34621.1 - 7.3e-106 346.2 251.4 1.4e-09 38.0 7.7 16.2 16 0 0 16 16 16 14 Calcium-binding EGF domain FXa_inhibition PF14670.6 EGC34621.1 - 7.3e-100 326.9 253.2 1.7e-12 47.4 12.4 15.8 16 0 0 16 16 16 13 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGC34621.1 - 3.9e-95 311.2 134.9 1.4e-09 37.6 1.0 15.2 14 0 0 14 14 14 14 Complement Clr-like EGF-like EGF_3 PF12947.7 EGC34621.1 - 8.3e-23 80.3 221.8 0.0019 18.3 12.4 17.8 18 1 0 18 18 18 13 EGF domain hEGF PF12661.7 EGC34621.1 - 5.7e-09 36.3 193.3 0.041 14.5 1.9 17.6 17 1 0 17 17 17 12 Human growth factor-like EGF TIG PF01833.24 EGC34621.1 - 9e-06 25.7 25.6 1.6e-05 24.9 0.2 5.1 5 0 0 5 5 5 3 IPT/TIG domain EGF PF00008.27 EGC34621.1 - 6.2e-05 23.2 220.6 0.33 11.3 5.8 17.2 16 1 0 16 16 16 12 EGF-like domain DUF4375 PF14300.6 EGC34621.1 - 0.00075 19.7 0.6 82 3.5 0.0 5.5 4 1 1 5 5 5 0 Domain of unknown function (DUF4375) GBP PF02263.19 EGC34622.1 - 8.3e-45 153.1 0.4 8.3e-45 153.1 0.4 2.9 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGC34622.1 - 0.015 15.3 0.0 0.054 13.6 0.0 2.0 1 0 0 1 1 1 0 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC34622.1 - 0.17 11.9 0.1 0.17 11.9 0.1 3.0 3 1 0 3 3 3 0 Dynamin family SLAC1 PF03595.17 EGC34623.1 - 7e-20 71.5 48.4 8.9e-20 71.2 48.4 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DEP PF00610.21 EGC34623.1 - 0.00075 19.5 0.0 0.002 18.1 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SLAC1 PF03595.17 EGC34624.1 - 9.5e-20 71.1 44.9 1.1e-19 70.9 44.9 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel AKAP2_C PF15304.6 EGC34624.1 - 0.022 14.1 0.4 0.03 13.6 0.4 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus Hum_adeno_E3A PF05393.11 EGC34624.1 - 0.85 9.6 6.4 0.47 10.5 0.3 3.2 2 1 1 3 3 3 0 Human adenovirus early E3A glycoprotein Glyco_hydro_18 PF00704.28 EGC34625.1 - 3.7e-31 109.0 0.0 4.6e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FNIP PF05725.12 EGC34626.1 - 4.2e-26 90.8 84.5 1.6e-08 34.5 1.0 9.5 8 1 2 10 10 10 7 FNIP Repeat STAT2_C PF12188.8 EGC34626.1 - 0.011 15.7 0.8 4.4 7.3 0.0 4.1 4 0 0 4 4 4 0 Signal transducer and activator of transcription 2 C terminal Glucosamine_iso PF01182.20 EGC34627.1 - 7e-45 153.6 0.0 8.2e-45 153.4 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase N6-adenineMlase PF10237.9 EGC34627.1 - 0.037 13.9 0.0 0.049 13.4 0.0 1.3 1 1 0 1 1 1 0 Probable N6-adenine methyltransferase SSPI PF14098.6 EGC34627.1 - 0.15 12.2 0.5 3.8 7.7 0.1 2.5 2 0 0 2 2 2 0 Small, acid-soluble spore protein I GRAM PF02893.20 EGC34628.1 - 1.1e-12 47.8 1.2 3.2e-07 30.2 0.5 2.4 2 0 0 2 2 2 2 GRAM domain bPH_3 PF14470.6 EGC34628.1 - 5.7e-10 39.4 2.2 4.4e-05 23.8 1.2 2.4 2 0 0 2 2 2 2 Bacterial PH domain Myosin_TH1 PF06017.13 EGC34628.1 - 0.016 14.9 2.4 0.46 10.1 0.1 2.5 2 0 0 2 2 2 0 Unconventional myosin tail, actin- and lipid-binding DUF956 PF06115.11 EGC34628.1 - 0.065 12.9 0.3 0.31 10.8 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF956) DUF908 PF06012.12 EGC34628.1 - 3.4 7.0 16.7 7 5.9 16.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Totivirus_coat PF05518.11 EGC34628.1 - 6.7 4.6 6.3 9.3 4.2 6.3 1.1 1 0 0 1 1 1 0 Totivirus coat protein AhpC-TSA PF00578.21 EGC34629.1 - 1.7e-29 102.3 0.1 2.3e-29 101.9 0.1 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.9 EGC34629.1 - 1.2e-13 50.6 0.1 3.1e-13 49.3 0.1 1.8 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.10 EGC34629.1 - 5.1e-10 39.2 0.0 7.2e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Redoxin SCO1-SenC PF02630.14 EGC34629.1 - 0.054 13.4 0.1 0.081 12.8 0.1 1.4 1 0 0 1 1 1 0 SCO1/SenC Thioredoxin_8 PF13905.6 EGC34629.1 - 0.073 13.4 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like hNIFK_binding PF12196.8 EGC34629.1 - 2 8.0 4.1 34 4.0 4.1 2.4 1 1 0 1 1 1 0 FHA Ki67 binding domain of hNIFK ADH_N PF08240.12 EGC34630.1 - 3.6e-20 71.9 1.4 6.8e-20 71.0 1.4 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC34630.1 - 9.6e-12 45.0 0.0 2.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGC34630.1 - 0.043 13.2 0.2 0.077 12.3 0.2 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2383 PF09537.10 EGC34631.1 - 9.3e-14 51.7 0.0 1.6e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF892 PF05974.12 EGC34631.1 - 2.5e-07 30.8 0.5 3.1e-05 24.0 0.1 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF892) Ferritin PF00210.24 EGC34631.1 - 5.1e-06 26.5 2.2 0.00045 20.2 0.4 2.1 2 0 0 2 2 2 2 Ferritin-like domain DUF3231 PF11553.8 EGC34631.1 - 0.0051 16.5 0.1 0.013 15.1 0.0 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3231) S4 PF01479.25 EGC34632.1 - 0.00035 20.2 0.0 0.0012 18.5 0.0 1.9 2 0 0 2 2 2 1 S4 domain Rep_fac_C PF08542.11 EGC34633.1 - 3.5e-17 62.6 0.0 8e-17 61.4 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGC34633.1 - 1.7e-16 60.9 0.0 2.8e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGC34633.1 - 4.6e-11 42.8 0.0 6.3e-08 32.6 0.1 2.4 1 1 1 2 2 2 2 DNA polymerase III, delta subunit Rad17 PF03215.15 EGC34633.1 - 1.2e-06 28.6 0.1 0.00012 22.0 0.1 2.7 1 1 0 1 1 1 1 Rad17 P-loop domain AAA_7 PF12775.7 EGC34633.1 - 5e-05 22.9 0.0 0.0001 21.8 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_16 PF13191.6 EGC34633.1 - 7.3e-05 23.2 0.0 0.00014 22.3 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC34633.1 - 9.4e-05 22.7 0.1 0.021 15.1 0.0 2.6 1 1 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGC34633.1 - 9.6e-05 22.2 0.0 0.0002 21.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGC34633.1 - 0.00021 21.3 0.0 0.00049 20.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGC34633.1 - 0.00033 20.5 0.0 0.00062 19.6 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGC34633.1 - 0.00042 20.1 0.0 0.00098 18.9 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_24 PF13479.6 EGC34633.1 - 0.00056 19.7 0.0 0.0011 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.6 EGC34633.1 - 0.001 18.9 0.0 0.003 17.4 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC34633.1 - 0.0011 19.0 0.0 0.0035 17.4 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.6 EGC34633.1 - 0.0011 19.3 0.1 0.0061 16.9 0.1 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC34633.1 - 0.0015 19.1 0.0 0.0033 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_23 PF13476.6 EGC34633.1 - 0.0033 17.9 0.2 0.0082 16.7 0.2 1.8 1 1 0 1 1 1 1 AAA domain AAA_assoc_2 PF16193.5 EGC34633.1 - 0.0034 17.7 0.0 0.0081 16.5 0.0 1.6 1 0 0 1 1 1 1 AAA C-terminal domain Viral_helicase1 PF01443.18 EGC34633.1 - 0.0039 16.9 0.0 0.0061 16.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.17 EGC34633.1 - 0.0052 16.5 0.0 0.015 15.1 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF815 PF05673.13 EGC34633.1 - 0.0099 15.1 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 EGC34633.1 - 0.014 14.8 0.1 0.91 8.9 0.0 2.5 2 1 1 3 3 3 0 Bacterial TniB protein AAA_28 PF13521.6 EGC34633.1 - 0.014 15.6 0.0 0.027 14.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC34633.1 - 0.015 15.6 0.0 0.034 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase ATPase_2 PF01637.18 EGC34633.1 - 0.046 13.6 0.0 0.1 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGC34633.1 - 0.049 14.2 0.0 0.15 12.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter DNA_pol3_delta PF06144.13 EGC34633.1 - 0.051 13.4 0.1 0.086 12.6 0.1 1.3 1 0 0 1 1 1 0 DNA polymerase III, delta subunit ResIII PF04851.15 EGC34633.1 - 0.057 13.4 0.0 0.18 11.8 0.0 1.8 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit Mg_chelatase PF01078.21 EGC34633.1 - 0.062 12.7 0.0 0.2 11.0 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PIF1 PF05970.14 EGC34633.1 - 0.077 12.1 0.0 2 7.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase Thymidylate_kin PF02223.17 EGC34633.1 - 0.082 12.6 0.0 0.86 9.2 0.0 2.1 1 1 0 2 2 2 0 Thymidylate kinase L27_N PF09060.10 EGC34633.1 - 0.089 12.9 0.0 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 L27_N SRP54 PF00448.22 EGC34633.1 - 0.13 11.8 0.0 0.27 10.8 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGC34633.1 - 0.14 11.9 0.0 0.4 10.5 0.0 1.7 2 0 0 2 2 1 0 P-loop containing region of AAA domain UPRTase PF14681.6 EGC34634.1 - 6.4e-81 270.7 0.0 7.3e-81 270.5 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.27 EGC34634.1 - 9.2e-08 31.8 0.0 1.5e-07 31.1 0.0 1.4 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.6 EGC34634.1 - 0.086 12.3 0.0 0.13 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphoribosyl transferase DNA_pol_E_B PF04042.16 EGC34635.1 - 5e-38 130.6 0.1 1.1e-37 129.5 0.1 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DNA_pol_D_N PF18018.1 EGC34635.1 - 6.2e-37 126.6 0.0 1.5e-36 125.4 0.0 1.7 1 0 0 1 1 1 1 DNA polymerase delta subunit OB-fold domain RRM_1 PF00076.22 EGC34635.1 - 0.055 13.3 0.2 9.6 6.1 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_IV PF11411.8 EGC34635.1 - 0.15 12.2 0.5 0.31 11.2 0.5 1.5 1 0 0 1 1 1 0 DNA ligase IV DUF3446 PF11928.8 EGC34635.1 - 0.84 10.0 8.6 2.3 8.6 8.6 1.7 1 0 0 1 1 1 0 Early growth response N-terminal domain ArfGap PF01412.18 EGC34637.1 - 1.2e-32 112.5 0.2 1.2e-32 112.5 0.2 4.0 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Alpha-amylase PF00128.24 EGC34638.1 - 1.1e-56 192.8 4.2 2.4e-56 191.7 0.5 2.2 2 0 0 2 2 2 1 Alpha amylase, catalytic domain GHL6 PF14871.6 EGC34638.1 - 0.13 12.4 0.0 0.51 10.5 0.0 2.1 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF3430 PF11912.8 EGC34639.1 - 0.036 14.1 20.4 0.3 11.1 20.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) CarboxypepD_reg PF13620.6 EGC34640.1 - 6e-19 68.1 0.0 0.069 13.4 0.0 8.3 8 0 0 8 8 8 5 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EGC34640.1 - 3.4e-08 33.7 17.7 0.063 13.5 0.0 8.0 9 1 0 9 9 9 3 SdrD B-like domain CarbopepD_reg_2 PF13715.6 EGC34640.1 - 4e-05 23.5 22.8 0.97 9.5 0.1 8.4 9 0 0 9 9 9 4 CarboxypepD_reg-like domain DUF2012 PF09430.10 EGC34640.1 - 0.00027 21.1 8.8 8.5 6.5 0.1 6.5 6 1 1 7 7 7 2 Protein of unknown function (DUF2012) DUF2615 PF11027.8 EGC34640.1 - 0.039 14.1 0.1 0.086 13.0 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2615) WBP-1 PF11669.8 EGC34640.1 - 0.21 12.2 0.7 3.4 8.3 0.1 2.8 2 0 0 2 2 2 0 WW domain-binding protein 1 TMEMspv1-c74-12 PF11044.8 EGC34640.1 - 4.3 7.4 6.3 12 6.0 1.8 2.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Methyltransf_24 PF13578.6 EGC34641.1 - 0.00032 21.7 0.0 0.00077 20.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC34641.1 - 0.00065 20.4 0.0 0.00065 20.4 0.0 3.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC34641.1 - 0.00078 19.3 0.0 0.0011 18.7 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34641.1 - 0.0043 17.7 0.0 0.0078 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGC34641.1 - 0.017 14.8 0.0 0.03 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Mem_trans PF03547.18 EGC34641.1 - 0.068 11.6 0.2 0.095 11.1 0.2 1.2 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_11 PF08241.12 EGC34641.1 - 0.18 12.5 0.0 0.34 11.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Presenilin PF01080.17 EGC34641.1 - 5.4 5.7 5.8 7 5.3 5.8 1.1 1 0 0 1 1 1 0 Presenilin p450 PF00067.22 EGC34642.1 - 4.4e-94 315.8 0.0 5e-94 315.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4199 PF13858.6 EGC34642.1 - 0.12 12.7 1.1 23 5.3 0.3 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) UCH PF00443.29 EGC34643.1 - 1.2e-42 146.2 5.2 1.2e-42 146.2 5.2 6.5 5 2 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC34643.1 - 2.5e-20 73.3 7.2 2.5e-20 73.3 7.2 7.4 6 2 0 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase Zn_ribbon_17 PF17120.5 EGC34643.1 - 1.3e-11 43.9 11.9 3.6e-11 42.5 11.9 1.8 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zinc_ribbon_16 PF17034.5 EGC34643.1 - 0.00011 22.4 6.4 0.00011 22.4 6.4 3.6 2 1 1 3 3 3 1 Zinc-ribbon like family IL5 PF02025.15 EGC34643.1 - 0.31 11.4 4.4 0.13 12.6 0.4 2.5 2 0 0 2 2 2 0 Interleukin 5 Trypan_PARP PF05887.11 EGC34644.1 - 6.3 6.8 12.9 6.6 6.7 12.9 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) PIP5K PF01504.18 EGC34645.1 - 1.7e-96 322.7 1.0 1.7e-96 322.7 1.0 2.4 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3439 PF11921.8 EGC34645.1 - 0.37 10.8 2.4 0.96 9.4 2.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Pkinase PF00069.25 EGC34646.1 - 1.6e-26 93.3 0.1 1.8e-26 93.1 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34646.1 - 1.9e-17 63.4 0.0 2.2e-17 63.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC34646.1 - 0.0016 17.3 0.1 0.0019 17.0 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC34646.1 - 0.0051 15.8 0.2 0.0067 15.4 0.2 1.1 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC34646.1 - 0.014 14.8 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGC34646.1 - 0.12 11.7 1.0 0.17 11.2 1.0 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC34646.1 - 0.19 11.6 0.6 0.24 11.3 0.6 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.12 EGC34647.1 - 1.9e-60 200.8 112.6 1.3e-08 34.9 0.8 16.6 9 3 12 21 21 21 19 FNIP Repeat Pkinase PF00069.25 EGC34647.1 - 6.3e-50 170.0 3.5 5.1e-25 88.3 0.8 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34647.1 - 9.5e-38 130.0 0.0 3.9e-19 69.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC34647.1 - 2.2e-06 26.7 0.4 0.014 14.2 0.0 2.2 2 0 0 2 2 2 2 Fungal protein kinase APH PF01636.23 EGC34647.1 - 1.5e-05 25.1 0.4 0.029 14.3 0.0 2.8 2 1 1 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.14 EGC34647.1 - 9.9e-05 21.8 0.3 0.0096 15.3 0.1 2.2 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC34647.1 - 0.00014 21.0 3.7 0.0022 17.0 0.5 2.2 2 0 0 2 2 2 2 Haspin like kinase domain RIO1 PF01163.22 EGC34647.1 - 0.00083 19.0 1.1 0.062 12.9 0.2 2.5 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.6 EGC34647.1 - 0.0053 16.1 0.0 2.5 7.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Pkinase PF00069.25 EGC34648.1 - 2.4e-77 259.9 8.7 8.3e-41 140.1 0.2 5.2 5 0 0 5 5 5 4 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34648.1 - 9.7e-39 133.2 0.6 7.9e-15 54.8 0.1 4.5 4 0 0 4 4 4 4 Protein tyrosine kinase tRNA-synt_His PF13393.6 EGC34648.1 - 6.5e-19 68.3 0.0 1.1e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.7 EGC34648.1 - 8e-18 64.9 3.6 8e-18 64.9 3.6 5.2 5 2 0 5 5 5 1 Anticodon binding domain of tRNAs RWD PF05773.22 EGC34648.1 - 9e-16 58.2 0.3 9e-16 58.2 0.3 4.3 4 0 0 4 4 4 1 RWD domain HGTP_anticodon PF03129.20 EGC34648.1 - 4.7e-07 29.9 0.0 1.2e-06 28.6 0.0 1.7 1 0 0 1 1 1 1 Anticodon binding domain APH PF01636.23 EGC34648.1 - 0.0046 16.9 0.0 0.049 13.5 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC34648.1 - 0.014 14.8 0.1 0.041 13.2 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC34648.1 - 0.052 12.9 0.1 0.56 9.5 0.0 2.3 2 0 0 2 2 2 0 Kinase-like GRAM PF02893.20 EGC34649.1 - 8.5e-15 54.6 0.3 2.1e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.8 EGC34649.1 - 3.2e-08 33.7 6.7 8.6e-08 32.4 0.5 2.7 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 EGC34649.1 - 0.0011 18.9 6.4 0.017 15.1 0.5 2.5 2 0 0 2 2 2 2 SNARE domain DUF5089 PF17002.5 EGC34649.1 - 0.032 14.1 0.4 0.032 14.1 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5089) Snapin_Pallidin PF14712.6 EGC34649.1 - 1.5 9.2 7.2 5.4 7.5 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Ank_2 PF12796.7 EGC34650.1 - 0.0018 18.8 0.1 8.2 7.1 0.0 4.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) LRR_4 PF12799.7 EGC34652.1 - 1.8e-18 66.3 51.7 3.4e-07 30.5 5.0 4.5 1 1 6 7 7 7 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC34652.1 - 1e-09 38.0 21.3 5.2e-07 29.3 5.0 4.2 2 1 1 4 4 4 2 Leucine rich repeat LRR_9 PF14580.6 EGC34652.1 - 1.9e-09 37.3 16.7 9.8e-08 31.7 6.7 3.1 1 1 2 3 3 3 2 Leucine-rich repeat DUF2322 PF10084.9 EGC34652.1 - 0.033 14.2 0.3 0.14 12.2 0.0 2.2 3 0 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) mCpol PF18182.1 EGC34652.1 - 0.13 12.6 5.9 0.18 12.1 0.0 3.2 1 1 3 4 4 4 0 minimal CRISPR polymerase domain DUF3199 PF11436.8 EGC34652.1 - 0.45 10.6 4.6 1.1 9.2 0.4 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF3199) LRR_1 PF00560.33 EGC34652.1 - 4.8 8.1 23.0 20 6.2 0.3 6.5 6 1 0 6 6 6 0 Leucine Rich Repeat LRR_2 PF07723.13 EGC34652.1 - 6.1 7.7 6.5 3.7 8.4 0.2 3.4 3 1 1 4 4 4 0 Leucine Rich Repeat NmrA PF05368.13 EGC34653.1 - 1.3e-42 146.0 0.1 1.6e-42 145.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC34653.1 - 8e-09 35.6 0.0 1.2e-08 35.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Ribosomal_L24e PF01246.20 EGC34654.1 - 4.4e-33 113.3 5.6 1.1e-32 112.1 5.6 1.7 1 0 0 1 1 1 1 Ribosomal protein L24e Ras PF00071.22 EGC34655.1 - 1.3e-48 164.6 0.0 1.6e-48 164.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34655.1 - 4.3e-22 78.6 0.0 8e-22 77.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34655.1 - 1.4e-06 27.9 0.0 1.9e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1681 PF07933.14 EGC34656.1 - 7e-55 184.8 0.0 1.1e-54 184.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1681) Dicty_CAR PF05462.11 EGC34657.1 - 8.7e-15 54.6 20.2 8.7e-15 54.6 20.2 2.2 2 1 1 3 3 3 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.24 EGC34657.1 - 4.7e-10 39.2 21.9 1.1e-09 38.0 21.9 1.6 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.17 EGC34657.1 - 1e-05 24.7 22.6 0.0018 17.4 0.4 2.6 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region GPR_Gpa2_C PF11970.8 EGC34657.1 - 0.0025 17.9 1.3 0.0053 16.8 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term 7tm_1 PF00001.21 EGC34657.1 - 0.016 14.5 24.9 0.032 13.5 24.9 1.5 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Phage_TAC_13 PF16459.5 EGC34657.1 - 0.14 12.6 0.1 0.28 11.7 0.1 1.5 1 0 0 1 1 1 0 Phage tail assembly chaperone, TAC LRR_4 PF12799.7 EGC34658.1 - 8e-14 51.5 22.1 5.1e-08 33.1 2.5 3.4 1 1 3 4 4 4 4 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC34658.1 - 3.1e-13 49.6 0.6 7.8e-12 45.0 0.0 2.2 1 1 1 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EGC34658.1 - 5.2e-09 35.7 17.0 1.2e-05 25.0 4.5 2.6 1 1 2 3 3 3 3 Leucine rich repeat LRR_6 PF13516.6 EGC34658.1 - 0.025 14.6 4.0 4.3 7.6 0.0 3.8 4 0 0 4 4 4 0 Leucine Rich repeat DUF3439 PF11921.8 EGC34658.1 - 0.18 11.8 3.5 0.35 10.8 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LRR_1 PF00560.33 EGC34658.1 - 0.34 11.6 11.6 29 5.7 0.3 4.3 3 1 1 4 4 4 0 Leucine Rich Repeat Tir_receptor_C PF07489.11 EGC34658.1 - 0.35 10.8 13.0 0.84 9.6 13.0 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ribosomal_L37ae PF01780.19 EGC34659.1 - 2.2e-41 139.9 9.1 2.4e-41 139.7 9.1 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.7 EGC34659.1 - 0.0004 20.3 1.3 0.00062 19.7 1.3 1.3 1 0 0 1 1 1 1 Transposase zinc-ribbon domain DUF1451 PF07295.11 EGC34659.1 - 0.003 17.6 0.9 0.004 17.2 0.9 1.1 1 0 0 1 1 1 1 Zinc-ribbon containing domain zf-RING_13 PF17977.1 EGC34659.1 - 0.037 14.1 2.5 0.051 13.7 2.5 1.2 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain C1_2 PF03107.16 EGC34659.1 - 0.041 14.2 2.9 0.61 10.4 3.1 2.0 1 1 0 1 1 1 0 C1 domain VATC PF18716.1 EGC34659.1 - 0.077 12.9 0.6 1.9 8.4 0.1 2.2 2 0 0 2 2 2 0 Vms1-associating treble clef domain ZZ PF00569.17 EGC34659.1 - 0.1 12.4 1.1 10 6.0 0.1 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-BED PF02892.15 EGC34659.1 - 0.13 12.3 4.7 1.5 8.9 0.4 2.2 1 1 1 2 2 2 0 BED zinc finger A2L_zn_ribbon PF08792.10 EGC34659.1 - 0.3 10.8 3.4 3 7.7 0.1 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-H2C2_2 PF13465.6 EGC34659.1 - 0.51 10.9 4.3 1.4 9.5 0.7 2.2 1 1 1 2 2 2 0 Zinc-finger double domain zf-Sec23_Sec24 PF04810.15 EGC34659.1 - 0.92 9.6 5.4 5.2 7.2 0.2 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger HSF_DNA-bind PF00447.17 EGC34660.1 - 4.8e-28 97.6 5.2 2.8e-27 95.2 0.4 2.2 2 0 0 2 2 2 1 HSF-type DNA-binding ZapB PF06005.12 EGC34660.1 - 0.012 16.0 2.8 0.023 15.1 2.8 1.4 1 0 0 1 1 1 0 Cell division protein ZapB WXG100 PF06013.12 EGC34660.1 - 0.018 15.3 0.6 0.032 14.5 0.6 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG SKA2 PF16740.5 EGC34660.1 - 0.03 14.1 3.1 0.06 13.1 3.1 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 2 JAKMIP_CC3 PF16034.5 EGC34660.1 - 0.051 13.5 5.9 0.28 11.1 5.9 2.0 1 1 0 1 1 1 0 JAKMIP CC3 domain MbeD_MobD PF04899.12 EGC34660.1 - 0.49 10.6 6.6 0.83 9.8 6.6 1.4 1 0 0 1 1 1 0 MbeD/MobD like PYST-C1 PF09690.10 EGC34660.1 - 10 6.0 9.0 1.5 8.6 3.5 2.1 2 0 0 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) BST2 PF16716.5 EGC34661.1 - 0.028 15.0 1.8 0.028 15.0 1.8 4.3 2 1 2 4 4 4 0 Bone marrow stromal antigen 2 TMF_DNA_bd PF12329.8 EGC34661.1 - 0.028 14.4 7.5 0.028 14.4 7.5 4.9 3 2 1 4 4 4 0 TATA element modulatory factor 1 DNA binding DUF1269 PF06897.12 EGC34661.1 - 0.66 10.3 4.7 4.9 7.5 1.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1269) DUF1284 PF06935.11 EGC34661.1 - 2.8 8.4 11.6 0.057 13.8 1.4 2.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1284) UPF0227 PF05728.12 EGC34661.1 - 4.3 7.2 8.5 0.69 9.8 2.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) TFIIIC_sub6 PF10419.9 EGC34662.1 - 3.9e-13 49.1 7.5 1e-12 47.7 6.2 2.4 1 1 0 1 1 1 1 TFIIIC subunit triple barrel domain NEXCaM_BD PF16644.5 EGC34663.1 - 0.076 13.3 4.4 0.27 11.5 4.4 2.0 1 0 0 1 1 1 0 Regulatory region of Na+/H+ exchanger NHE binds to calmodulin Prefoldin PF02996.17 EGC34664.1 - 2.8e-23 82.1 2.5 2.8e-23 82.1 2.5 1.5 1 1 0 1 1 1 1 Prefoldin subunit ApoO PF09769.9 EGC34664.1 - 0.23 11.5 1.6 4.8 7.1 0.1 2.2 2 0 0 2 2 2 0 Apolipoprotein O Nas2_N PF18265.1 EGC34664.1 - 0.24 11.4 2.8 2.5 8.1 1.3 2.2 2 0 0 2 2 2 0 Nas2 N_terminal domain DUF1192 PF06698.11 EGC34664.1 - 0.67 10.1 5.4 0.17 12.0 1.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Vps51 PF08700.11 EGC34664.1 - 7.9 6.6 11.0 0.29 11.2 2.6 2.2 2 0 0 2 2 2 0 Vps51/Vps67 RhoGAP PF00620.27 EGC34665.1 - 2.6e-32 111.8 3.5 2.9e-32 111.6 0.5 2.5 2 0 0 2 2 2 1 RhoGAP domain RCC1_2 PF13540.6 EGC34665.1 - 3.7e-28 96.7 23.8 8e-06 25.5 1.0 6.8 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGC34665.1 - 5.5e-25 87.7 17.7 3.3e-10 40.4 0.1 7.9 7 2 0 7 7 7 3 Regulator of chromosome condensation (RCC1) repeat HALZ PF02183.18 EGC34665.1 - 0.3 11.4 3.4 0.45 10.8 1.7 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper End3 PF12761.7 EGC34665.1 - 0.33 11.1 7.6 0.81 9.8 7.6 1.6 1 0 0 1 1 1 0 Actin cytoskeleton-regulatory complex protein END3 CLZ PF16526.5 EGC34665.1 - 2.8 8.4 6.1 6.6 7.2 0.3 2.7 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels FapA PF03961.13 EGC34665.1 - 4.6 5.7 7.5 5.4 5.5 4.5 2.2 2 0 0 2 2 2 0 Flagellar Assembly Protein A DASH_Duo1 PF08651.10 EGC34665.1 - 9.7 6.1 13.5 0.43 10.4 1.8 3.9 4 0 0 4 4 4 0 DASH complex subunit Duo1 Oxysterol_BP PF01237.18 EGC34666.1 - 1.2e-52 179.0 9.6 9.8e-50 169.4 9.6 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein FAM60A PF15396.6 EGC34666.1 - 0.061 13.3 1.0 0.12 12.4 1.0 1.4 1 0 0 1 1 1 0 Protein Family FAM60A Imm51 PF15595.6 EGC34667.1 - 0.0031 17.4 0.3 0.014 15.3 0.3 2.2 1 0 0 1 1 1 1 Immunity protein 51 Ank_2 PF12796.7 EGC34669.1 - 8e-06 26.4 0.0 3.1e-05 24.5 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) CTD_bind PF04818.13 EGC34669.1 - 1e-05 26.2 0.9 0.0001 23.0 0.6 2.9 2 0 0 2 2 2 1 RNA polymerase II-binding domain. F-box-like PF12937.7 EGC34669.1 - 0.00019 21.2 0.0 0.0004 20.2 0.0 1.6 1 0 0 1 1 1 1 F-box-like Ank_4 PF13637.6 EGC34669.1 - 0.0017 18.8 0.1 0.024 15.2 0.0 2.9 2 1 0 3 3 3 1 Ankyrin repeats (many copies) F-box PF00646.33 EGC34669.1 - 0.0028 17.5 0.1 0.017 15.0 0.0 2.4 2 0 0 2 2 2 1 F-box domain Tyrosinase PF00264.20 EGC34669.1 - 0.22 11.8 7.0 0.5 10.6 7.0 1.6 1 0 0 1 1 1 0 Common central domain of tyrosinase Apc15p PF05841.11 EGC34669.1 - 0.39 11.5 10.4 0.88 10.4 10.4 1.6 1 0 0 1 1 1 0 Apc15p protein DUF4834 PF16118.5 EGC34669.1 - 0.91 10.5 8.4 2.6 9.1 7.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Menin PF05053.13 EGC34669.1 - 5.9 5.1 12.1 11 4.3 12.1 1.3 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 EGC34669.1 - 7.5 7.2 21.2 27 5.4 21.2 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain SLT PF01464.20 EGC34670.1 - 6.4e-08 32.3 0.0 1.2e-07 31.4 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGC34670.1 - 0.0029 17.8 1.5 0.089 13.0 1.5 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SPX PF03105.19 EGC34670.1 - 9.4 6.0 12.3 11 5.8 12.3 1.1 1 0 0 1 1 1 0 SPX domain AMPK1_CBM PF16561.5 EGC34673.1 - 4.6e-35 119.7 0.3 4.6e-35 119.7 0.3 2.3 2 1 0 2 2 2 1 Glycogen recognition site of AMP-activated protein kinase AMPKBI PF04739.15 EGC34673.1 - 1.1e-19 70.4 5.4 1.1e-19 70.4 5.4 2.4 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interaction domain CBM_48 PF02922.18 EGC34673.1 - 0.0088 16.4 0.1 0.023 15.0 0.1 1.7 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) EMC3_TMCO1 PF01956.16 EGC34673.1 - 0.19 11.5 12.2 0.15 11.8 9.7 1.9 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like TERB2 PF15101.6 EGC34673.1 - 1.3 9.0 19.5 2.2 8.3 19.5 1.3 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Exonuc_VII_L PF02601.15 EGC34673.1 - 1.4 8.5 16.2 1.9 8.0 16.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Pex14_N PF04695.13 EGC34673.1 - 1.6 9.4 24.7 1.2 9.7 22.3 2.0 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region V_ATPase_I PF01496.19 EGC34673.1 - 1.7 6.5 9.3 2.3 6.0 9.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family GREB1 PF15782.5 EGC34673.1 - 4.2 4.4 14.6 5.2 4.1 14.6 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer AceK PF06315.11 EGC34673.1 - 5 5.5 11.0 7.2 5.0 11.0 1.1 1 0 0 1 1 1 0 Isocitrate dehydrogenase kinase/phosphatase (AceK) TFIIA PF03153.13 EGC34673.1 - 6.6 6.6 39.5 9.7 6.1 39.5 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.9 EGC34673.1 - 7.1 4.8 28.2 9.2 4.4 28.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 G-alpha PF00503.20 EGC34674.1 - 3e-13 49.7 20.9 9.1e-12 44.8 1.6 2.9 2 1 0 2 2 2 2 G-protein alpha subunit Menin PF05053.13 EGC34674.1 - 1.3 7.2 14.7 4.7 5.4 8.8 2.1 2 0 0 2 2 2 0 Menin PDZ_3 PF17815.1 EGC34675.1 - 1.4e-39 135.3 0.8 2.3e-39 134.5 0.8 1.4 1 0 0 1 1 1 1 PDZ domain Trypsin_2 PF13365.6 EGC34675.1 - 6e-23 82.4 0.1 1.2e-22 81.4 0.1 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.26 EGC34675.1 - 6.7e-16 58.8 0.0 1.5e-15 57.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.6 EGC34675.1 - 5.9e-11 42.5 0.1 4.2e-09 36.6 0.0 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_6 PF17820.1 EGC34675.1 - 3.6e-06 26.7 0.4 0.0059 16.4 0.1 2.5 2 0 0 2 2 2 2 PDZ domain PDZ PF00595.24 EGC34675.1 - 5.7e-05 23.4 1.3 0.0021 18.3 0.1 2.5 2 0 0 2 2 2 1 PDZ domain PDZ_1 PF12812.7 EGC34675.1 - 0.057 13.4 0.2 5.4 7.1 0.0 3.2 2 0 0 2 2 2 0 PDZ-like domain Dynein_IC2 PF11540.8 EGC34676.1 - 1e-11 44.5 2.1 1.8e-11 43.8 0.5 2.3 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 WD40 PF00400.32 EGC34676.1 - 6.4e-09 36.3 18.5 0.0032 18.3 0.3 6.7 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34676.1 - 0.0038 17.5 0.0 0.049 13.9 0.0 2.6 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 4 WD40 domain BolA PF01722.18 EGC34677.1 - 1.2e-29 102.3 0.5 1.8e-29 101.9 0.5 1.2 1 0 0 1 1 1 1 BolA-like protein PI3Ka PF00613.20 EGC34678.1 - 4.6e-16 58.8 1.2 8.5e-15 54.6 1.2 2.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGC34678.1 - 1.6e-14 54.3 12.9 2.7e-12 47.0 1.6 3.9 2 1 1 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.21 EGC34678.1 - 2.1e-11 43.8 5.7 2.1e-11 43.8 5.7 2.0 2 0 0 2 2 2 1 FYVE zinc finger NinF PF05810.12 EGC34678.1 - 1.3 9.0 4.7 5.2 7.0 4.7 2.1 1 0 0 1 1 1 0 NinF protein Pyr_redox_2 PF07992.14 EGC34679.1 - 9.6e-52 176.0 3.1 1.1e-51 175.9 3.1 1.0 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC34679.1 - 1.1e-19 70.9 2.6 2.8e-17 62.9 0.1 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC34679.1 - 2.5e-16 60.0 1.5 2.5e-16 60.0 1.5 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGC34679.1 - 0.00034 20.1 0.8 0.019 14.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.14 EGC34679.1 - 0.00036 19.4 1.1 0.52 9.0 0.0 2.4 1 1 0 2 2 2 2 HI0933-like protein NAD_binding_7 PF13241.6 EGC34679.1 - 0.00077 19.9 0.4 0.0048 17.3 0.1 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding K_oxygenase PF13434.6 EGC34679.1 - 0.0012 18.1 0.5 0.022 13.9 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGC34679.1 - 0.011 15.0 0.7 0.026 13.8 0.2 1.8 2 0 0 2 2 2 0 Thi4 family FAD_binding_2 PF00890.24 EGC34679.1 - 0.015 14.4 3.4 1.2 8.2 1.5 2.6 1 1 1 2 2 2 0 FAD binding domain Shikimate_DH PF01488.20 EGC34679.1 - 0.25 11.4 1.2 0.91 9.6 0.1 2.1 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.22 EGC34679.1 - 1.5 7.8 9.7 3 6.8 2.1 3.4 2 2 2 4 4 4 0 Glucose inhibited division protein A FAD_binding_3 PF01494.19 EGC34679.1 - 4.8 6.3 6.1 6.6 5.9 1.1 2.9 2 2 1 3 3 3 0 FAD binding domain KH_8 PF17903.1 EGC34680.1 - 1.1e-28 99.1 0.0 3.6e-28 97.5 0.0 1.9 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGC34680.1 - 0.068 13.0 0.0 0.22 11.4 0.0 1.9 2 0 0 2 2 2 0 KH domain VIT1 PF01988.19 EGC34680.1 - 0.36 10.7 1.3 0.78 9.6 1.3 1.5 1 0 0 1 1 1 0 VIT family Peptidase_S10 PF00450.22 EGC34681.1 - 5.2e-99 332.5 7.4 6.2e-99 332.2 7.4 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.25 EGC34683.1 - 3.4e-54 184.0 0.0 4.9e-54 183.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34683.1 - 6.4e-24 84.6 0.0 8.7e-24 84.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC34683.1 - 3.8e-09 36.3 0.0 5.8e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.11 EGC34683.1 - 0.0013 17.8 0.7 0.0025 16.9 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 RIO1 PF01163.22 EGC34683.1 - 0.0033 17.0 0.0 0.0085 15.7 0.0 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.23 EGC34683.1 - 0.031 14.2 0.0 0.045 13.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coronavirus_5 PF05528.11 EGC34683.1 - 0.067 13.2 0.1 0.16 12.0 0.1 1.5 1 0 0 1 1 1 0 Coronavirus gene 5 protein Vir_act_alpha_C PF10400.9 EGC34684.1 - 0.35 11.6 1.7 47 4.8 0.0 2.8 2 0 0 2 2 2 0 Virulence activator alpha C-term Coiled PF05710.12 EGC34685.1 - 0.00023 21.9 7.0 0.00025 21.8 7.0 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC34686.1 - 1.4e-16 61.0 22.9 1.7e-16 60.8 22.9 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC34687.1 - 3.6e-25 88.6 26.4 4.1e-25 88.4 26.4 1.0 1 0 0 1 1 1 1 Coiled coil FNIP PF05725.12 EGC34688.1 - 6.7e-47 157.4 81.9 5.9e-12 45.6 4.4 11.7 9 2 2 11 11 11 10 FNIP Repeat Collagen PF01391.18 EGC34691.1 - 0.095 12.5 2.1 0.15 11.9 2.1 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) TAFH PF07531.14 EGC34691.1 - 0.17 12.0 0.1 0.17 12.0 0.1 3.3 2 0 0 2 2 2 0 NHR1 homology to TAF Mon1 PF03164.14 EGC34692.1 - 3.6e-128 428.1 22.5 4.2e-128 427.9 22.5 1.1 1 0 0 1 1 1 1 Trafficking protein Mon1 Arrestin_N PF00339.29 EGC34692.1 - 0.036 14.1 0.0 0.085 12.9 0.0 1.6 1 0 0 1 1 1 0 Arrestin (or S-antigen), N-terminal domain Mating_N PF12731.7 EGC34692.1 - 0.055 13.6 2.0 6.9 6.8 0.0 3.2 3 0 0 3 3 3 0 Mating-type protein beta 1 ALG3 PF05208.13 EGC34695.1 - 8.6e-53 180.0 33.2 1.8e-52 179.0 33.2 1.5 1 0 0 1 1 1 1 ALG3 protein DUF1295 PF06966.12 EGC34696.1 - 3e-43 148.0 2.3 3.6e-43 147.8 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.14 EGC34696.1 - 0.0001 22.7 1.6 0.00012 22.4 0.3 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2701 PF10857.8 EGC34696.1 - 0.092 12.8 1.6 0.57 10.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) U-box PF04564.15 EGC34697.1 - 2.1e-18 66.3 0.1 1e-17 64.1 0.1 2.3 1 0 0 1 1 1 1 U-box domain zf-NOSIP PF15906.5 EGC34697.1 - 0.0014 18.7 0.0 0.0028 17.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-finger of nitric oxide synthase-interacting protein zf-Nse PF11789.8 EGC34697.1 - 0.0058 16.4 0.0 0.024 14.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3439 PF11921.8 EGC34697.1 - 0.024 14.6 2.2 0.34 10.9 2.8 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Rtf2 PF04641.12 EGC34697.1 - 2.5 7.4 0.0 2.5 7.4 0.0 4.2 2 1 2 4 4 4 0 Rtf2 RING-finger SLC12 PF03522.15 EGC34697.1 - 9.7 5.1 34.2 0.37 9.7 22.7 2.3 2 0 0 2 2 2 0 Solute carrier family 12 Vps35 PF03635.17 EGC34698.1 - 1.4e-251 837.1 19.4 1.7e-251 836.9 19.4 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Aconitase_B_N PF11791.8 EGC34698.1 - 0.053 13.6 0.1 0.32 11.0 0.1 2.4 2 0 0 2 2 2 0 Aconitate B N-terminal domain YmgB PF10798.8 EGC34698.1 - 0.055 13.3 0.5 0.4 10.5 0.0 2.7 2 0 0 2 2 2 0 Biofilm development protein YmgB/AriR FliS PF02561.14 EGC34698.1 - 2.7 8.3 5.3 3.4 8.0 0.3 3.3 3 0 0 3 3 3 0 Flagellar protein FliS Peptidase_S10 PF00450.22 EGC34699.1 - 6.4e-67 226.8 9.2 1.1e-35 123.9 0.3 2.0 2 0 0 2 2 2 2 Serine carboxypeptidase Phage_int_SAM_4 PF13495.6 EGC34701.1 - 0.39 11.2 3.2 22 5.6 1.8 3.3 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain EGF_2 PF07974.13 EGC34701.1 - 1.5 9.3 16.0 0.12 12.8 11.1 1.8 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGC34702.1 - 0.036 14.4 12.4 0.024 15.0 9.8 2.0 2 0 0 2 2 2 0 EGF-like domain SieB PF14163.6 EGC34702.1 - 0.21 11.1 2.1 0.39 10.2 0.3 2.1 2 0 0 2 2 2 0 Super-infection exclusion protein B GW PF13457.6 EGC34702.1 - 1.2 9.8 7.4 4.1 8.1 3.8 3.3 3 0 0 3 3 3 0 GW (Gly-Tryp) dipeptide domain Insulin_TMD PF17870.1 EGC34703.1 - 0.034 14.2 0.8 0.11 12.6 0.8 1.9 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment EGF_2 PF07974.13 EGC34703.1 - 0.074 13.4 13.9 0.057 13.8 11.3 2.2 2 0 0 2 2 2 0 EGF-like domain GW PF13457.6 EGC34703.1 - 0.8 10.4 9.5 1.6 9.4 3.8 3.8 3 0 0 3 3 3 0 GW (Gly-Tryp) dipeptide domain EGF_2 PF07974.13 EGC34704.1 - 9.7e-05 22.7 10.4 9.7e-05 22.7 10.4 3.2 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 EGC34704.1 - 0.0065 16.6 25.4 0.049 13.8 8.2 3.1 2 0 0 2 2 2 2 Laminin EGF domain EGF_Tenascin PF18720.1 EGC34704.1 - 0.39 10.8 24.8 0.066 13.3 7.5 3.1 3 0 0 3 3 3 0 Tenascin EGF domain Acyl-CoA_dh_1 PF00441.24 EGC34705.1 - 1e-42 145.9 0.3 2.1e-42 144.9 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGC34705.1 - 1.5e-37 128.7 0.0 2.8e-37 127.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGC34705.1 - 6.5e-28 96.8 0.1 1.4e-27 95.7 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC34705.1 - 1e-13 51.7 0.0 3.2e-13 50.1 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.8 EGC34705.1 - 0.0007 19.3 0.1 0.0037 17.0 0.1 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal MobC PF05713.11 EGC34705.1 - 0.16 12.4 0.5 0.89 10.1 0.1 2.4 2 0 0 2 2 2 0 Bacterial mobilisation protein (MobC) Dopey_N PF04118.14 EGC34706.1 - 4.8e-93 311.6 7.0 4.8e-93 311.6 7.0 4.0 4 0 0 4 4 4 1 Dopey, N-terminal Nfu_N PF08712.11 EGC34706.1 - 0.64 10.1 3.5 0.71 10.0 0.3 2.8 2 0 0 2 2 2 0 Scaffold protein Nfu/NifU N terminal DUF3430 PF11912.8 EGC34708.1 - 2e-18 67.2 35.7 2.3e-18 67.0 35.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) WD40 PF00400.32 EGC34710.1 - 4.4e-49 163.4 23.5 1.8e-05 25.4 0.1 10.8 12 0 0 12 12 11 9 WD domain, G-beta repeat Utp13 PF08625.11 EGC34710.1 - 2.1e-40 137.9 0.3 4.4e-40 136.9 0.3 1.6 1 0 0 1 1 1 1 Utp13 specific WD40 associated domain ANAPC4_WD40 PF12894.7 EGC34710.1 - 6.4e-16 58.4 10.1 0.015 15.6 0.1 7.9 3 2 5 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC34710.1 - 2.6e-08 33.5 13.2 0.00035 20.0 0.1 4.4 3 1 1 4 4 4 4 WD40-like domain Nup160 PF11715.8 EGC34710.1 - 2.2e-07 30.0 17.2 0.12 11.0 0.3 7.0 2 2 6 8 8 8 4 Nucleoporin Nup120/160 Ge1_WD40 PF16529.5 EGC34710.1 - 0.00023 20.2 14.5 1 8.2 0.0 5.8 2 2 3 5 5 5 1 WD40 region of Ge1, enhancer of mRNA-decapping protein NUP214 PF16755.5 EGC34710.1 - 0.00025 20.4 6.3 0.00026 20.3 0.5 3.0 3 1 0 3 3 3 1 Nucleoporin or Nuclear pore complex subunit NUP214=Nup159 Str_synth PF03088.16 EGC34710.1 - 0.00037 20.6 0.0 1.3 9.2 0.0 3.2 2 0 0 2 2 2 2 Strictosidine synthase HPS3_N PF14761.6 EGC34710.1 - 0.00048 19.7 2.6 0.21 11.1 0.0 4.7 4 1 1 5 5 5 1 Hermansky-Pudlak syndrome 3 Nucleoporin_N PF08801.11 EGC34710.1 - 0.0074 15.1 0.1 0.0074 15.1 0.1 4.2 3 1 2 5 5 5 1 Nup133 N terminal like BBS2_Mid PF14783.6 EGC34710.1 - 0.028 14.5 3.1 15 5.6 0.1 5.1 3 1 2 5 5 5 0 Ciliary BBSome complex subunit 2, middle region TIG PF01833.24 EGC34711.1 - 7.4e-17 61.2 67.6 2e-05 24.6 2.3 8.3 8 0 0 8 8 8 6 IPT/TIG domain EGF_2 PF07974.13 EGC34711.1 - 0.02 15.2 12.0 0.051 14.0 12.0 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 EGC34711.1 - 0.11 12.6 8.1 0.26 11.4 8.1 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC34711.1 - 0.38 10.9 8.5 0.87 9.7 8.5 1.7 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 EGC34712.1 - 1.9e-93 306.7 121.7 2.7e-13 49.8 0.4 17.1 16 1 0 16 16 16 12 IPT/TIG domain YebO PF13974.6 EGC34713.1 - 0.016 15.3 1.4 0.026 14.6 0.2 1.8 1 1 1 2 2 2 0 YebO-like protein DUF3834 PF12916.7 EGC34713.1 - 0.019 14.3 0.2 0.021 14.1 0.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) Xpo1 PF08389.12 EGC34713.1 - 0.043 13.9 1.4 0.051 13.6 1.4 1.1 1 0 0 1 1 1 0 Exportin 1-like protein BUD22 PF09073.10 EGC34715.1 - 0.0023 17.4 23.1 0.0023 17.4 23.1 1.5 2 0 0 2 2 2 1 BUD22 SDA1 PF05285.12 EGC34715.1 - 0.42 10.0 37.7 0.072 12.5 27.2 2.2 2 0 0 2 2 2 0 SDA1 DUF533 PF04391.12 EGC34716.1 - 0.0031 17.1 0.0 0.0063 16.1 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF533) Rhomboid PF01694.22 EGC34716.1 - 0.018 15.0 0.3 0.03 14.3 0.3 1.3 1 0 0 1 1 1 0 Rhomboid family Mrpl_C PF18502.1 EGC34716.1 - 0.49 10.7 3.6 0.44 10.8 1.8 1.8 1 1 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain DUF5518 PF17647.1 EGC34716.1 - 4.8 7.4 12.4 1.2 9.3 5.6 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5518) RTC PF01137.21 EGC34717.1 - 3.4e-80 268.4 0.1 4.5e-80 268.0 0.1 1.2 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.13 EGC34717.1 - 3.5e-17 62.8 0.0 6.8e-17 61.9 0.0 1.5 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain CBM_25 PF03423.13 EGC34717.1 - 0.084 13.1 6.1 0.17 12.1 6.1 1.5 1 0 0 1 1 1 0 Carbohydrate binding domain (family 25) PadR PF03551.14 EGC34717.1 - 0.11 12.5 0.0 0.69 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator PadR-like family FSA_C PF10479.9 EGC34717.1 - 0.13 10.3 0.0 0.13 10.3 0.0 2.1 2 0 0 2 2 2 0 Fragile site-associated protein C-terminus Dicty_REP PF05086.12 EGC34717.1 - 0.23 9.4 12.1 0.34 8.8 12.1 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Guanylate_cyc PF00211.20 EGC34718.1 - 4.5e-25 88.3 0.1 1.3e-12 47.7 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain AAA_16 PF13191.6 EGC34718.1 - 1.4e-06 28.8 0.0 5.1e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain TPR_2 PF07719.17 EGC34718.1 - 0.0068 16.4 6.6 13 6.2 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC34718.1 - 0.067 13.5 3.9 1.2 9.5 0.1 4.0 4 1 1 5 5 5 0 Tetratricopeptide repeat NUDIX PF00293.28 EGC34719.1 - 1.1e-12 48.2 0.0 1.8e-12 47.4 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Pox_F15 PF04596.12 EGC34719.1 - 0.06 13.1 0.4 0.13 12.0 0.4 1.5 1 0 0 1 1 1 0 Poxvirus protein F15 Sde2_N_Ubi PF13019.6 EGC34720.1 - 3e-25 88.9 2.2 3e-25 88.9 2.2 2.4 2 1 1 3 3 3 1 Silencing defective 2 N-terminal ubiquitin domain DUF3439 PF11921.8 EGC34720.1 - 0.036 14.0 1.4 0.068 13.1 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DNA_pol_A PF00476.20 EGC34721.1 - 5.1e-102 341.7 0.7 6.3e-102 341.4 0.7 1.1 1 0 0 1 1 1 1 DNA polymerase family A Endonuc-PvuII PF09225.10 EGC34721.1 - 0.033 13.9 1.2 0.057 13.2 0.3 1.8 2 0 0 2 2 2 0 Restriction endonuclease PvuII DUF3800 PF12686.7 EGC34721.1 - 0.56 10.9 4.0 0.68 10.6 0.4 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3800) SR-25 PF10500.9 EGC34722.1 - 0.89 9.1 4.9 1.2 8.7 4.9 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein SpoU_methylase PF00588.19 EGC34723.1 - 4.5e-24 85.2 0.0 9.7e-24 84.2 0.0 1.6 1 0 0 1 1 1 1 SpoU rRNA Methylase family TAF8_C PF10406.9 EGC34725.1 - 2.1e-15 57.0 0.7 2.1e-15 57.0 0.7 3.2 3 0 0 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.13 EGC34725.1 - 1.4e-14 53.8 0.1 2.4e-14 53.1 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Trm112p PF03966.16 EGC34726.1 - 5.2e-13 49.4 0.1 7.8e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein DUF2325 PF10087.9 EGC34726.1 - 0.11 12.6 0.4 0.44 10.7 0.1 2.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2325) SRF-TF PF00319.18 EGC34727.1 - 2.5e-21 74.9 0.1 3.9e-21 74.3 0.1 1.3 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) ALMT PF11744.8 EGC34727.1 - 2 7.1 9.6 3.6 6.3 9.6 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter LMBR1 PF04791.16 EGC34727.1 - 3.4 6.5 7.7 4 6.3 7.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Membralin PF09746.9 EGC34727.1 - 5.7 5.9 8.6 11 5.0 8.6 1.4 1 0 0 1 1 1 0 Tumour-associated protein Erf4 PF10256.9 EGC34728.1 - 4e-15 55.9 1.6 5.7e-07 29.7 0.3 2.2 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF3671 PF12420.8 EGC34728.1 - 0.16 12.1 7.2 0.13 12.3 2.4 2.2 2 0 0 2 2 2 0 Protein of unknown function DUF3139 PF11337.8 EGC34728.1 - 0.66 10.7 10.1 0.42 11.3 1.4 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3139) BRCT PF00533.26 EGC34729.1 - 0.00096 19.5 2.3 0.0035 17.7 0.2 2.9 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Yop-YscD_cpl PF16697.5 EGC34729.1 - 0.031 14.6 0.0 0.079 13.3 0.0 1.6 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain BRCT_2 PF16589.5 EGC34729.1 - 0.039 14.3 0.1 0.039 14.3 0.1 4.1 2 1 1 3 3 3 0 BRCT domain, a BRCA1 C-terminus domain tRNA-synt_2 PF00152.20 EGC34730.1 - 2.9e-78 263.1 0.2 4.3e-78 262.6 0.2 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGC34730.1 - 9.8e-13 47.9 0.1 2e-12 46.9 0.1 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGC34730.1 - 5.8e-07 29.2 0.1 0.0027 17.2 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) TTL PF03133.15 EGC34731.1 - 2.9e-59 200.6 8.5 2.9e-59 200.6 8.5 2.1 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGC34731.1 - 2.4e-06 27.0 1.0 0.012 14.8 0.1 2.5 2 0 0 2 2 2 2 YheC/D like ATP-grasp ATPgrasp_ST PF14397.6 EGC34731.1 - 6.6e-05 22.3 0.1 0.0031 16.8 0.0 2.3 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp Dala_Dala_lig_C PF07478.13 EGC34731.1 - 0.0006 19.4 0.1 1.1 8.7 0.0 3.0 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus RimK PF08443.11 EGC34731.1 - 0.0076 15.9 0.3 0.034 13.7 0.0 2.0 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGC34731.1 - 0.091 12.8 0.0 3.9 7.5 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp domain Inhibitor_I34 PF10466.9 EGC34731.1 - 0.44 11.2 3.8 0.3 11.7 0.9 2.2 2 0 0 2 2 2 0 Saccharopepsin inhibitor I34 Cas9_PI2 PF18070.1 EGC34731.1 - 1.1 10.1 0.0 1.1 10.1 0.0 3.2 3 1 0 3 3 3 0 CRISPR-Cas9 PI domain Vinculin PF01044.19 EGC34732.1 - 1.2e-15 56.9 129.9 4.9e-11 41.6 35.6 6.2 1 1 0 2 2 2 2 Vinculin family Cloacin_immun PF03513.14 EGC34732.1 - 0.011 16.1 0.7 0.078 13.3 0.1 2.9 3 0 0 3 3 3 0 Cloacin immunity protein DUF434 PF04256.12 EGC34732.1 - 0.11 12.2 1.4 0.38 10.5 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF434) MetOD2 PF18548.1 EGC34732.1 - 0.3 11.2 0.0 0.3 11.2 0.0 6.9 6 2 1 7 7 7 0 Metanogen output domain 2 Exog_C PF18026.1 EGC34732.1 - 0.92 9.6 3.9 2.7 8.1 0.4 3.5 3 0 0 3 3 3 0 Endo/exonuclease (EXOG) C-terminal domain SNF2_N PF00176.23 EGC34733.1 - 9.3e-65 218.6 1.5 1.5e-64 217.9 0.0 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC34733.1 - 7.4e-22 77.8 0.1 8e-20 71.2 0.0 3.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CLP_protease PF00574.23 EGC34733.1 - 1.2 8.9 4.6 3.1 7.6 0.7 2.5 2 0 0 2 2 2 0 Clp protease CBM49 PF09478.10 EGC34734.1 - 9.2e-05 22.7 3.0 0.00014 22.1 3.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Ras PF00071.22 EGC34736.1 - 8.1e-37 126.3 0.5 1e-36 126.0 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34736.1 - 3e-18 66.2 0.1 3e-18 66.2 0.1 1.6 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase TbpB_B_D PF01298.18 EGC34736.1 - 0.85 10.0 5.6 1.7 9.1 2.6 2.6 2 1 1 3 3 3 0 C-lobe and N-lobe beta barrels of Tf-binding protein B RhoGAP PF00620.27 EGC34737.1 - 4.1e-29 101.4 0.2 9.3e-29 100.2 0.2 1.6 1 0 0 1 1 1 1 RhoGAP domain Exo_endo_phos PF03372.23 EGC34737.1 - 1.2e-13 51.1 0.0 1.9e-13 50.4 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Ndc1_Nup PF09531.10 EGC34737.1 - 0.036 12.8 2.7 0.056 12.1 2.7 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup TFIIA PF03153.13 EGC34737.1 - 0.32 10.9 10.1 0.5 10.3 10.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spore_II_R PF09551.10 EGC34738.1 - 0.0043 17.5 0.6 0.027 14.9 0.6 2.4 1 0 0 1 1 1 1 Stage II sporulation protein R (spore_II_R) DctQ PF04290.12 EGC34738.1 - 0.085 12.8 0.1 0.19 11.7 0.1 1.5 1 0 0 1 1 1 0 Tripartite ATP-independent periplasmic transporters, DctQ component Zn_dep_PLPC PF00882.18 EGC34738.1 - 1.3 9.0 8.4 0.68 9.9 0.4 3.3 3 0 0 3 3 3 0 Zinc dependent phospholipase C PAP_assoc PF03828.19 EGC34739.1 - 4.3e-09 36.5 0.6 1.1e-08 35.2 0.6 1.7 1 0 0 1 1 1 1 Cid1 family poly A polymerase Atg14 PF10186.9 EGC34740.1 - 0.053 12.6 1.1 0.068 12.2 1.1 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 MbeD_MobD PF04899.12 EGC34740.1 - 0.12 12.5 0.6 0.29 11.3 0.3 1.7 2 0 0 2 2 2 0 MbeD/MobD like Adeno_PV PF03910.13 EGC34740.1 - 0.18 10.5 1.9 0.25 10.0 1.9 1.2 1 0 0 1 1 1 0 Adenovirus minor core protein PV FlaC_arch PF05377.11 EGC34740.1 - 0.38 11.2 5.3 0.17 12.3 1.6 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) UPF0242 PF06785.11 EGC34740.1 - 0.49 10.5 10.5 0.034 14.3 5.5 1.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus BAR PF03114.18 EGC34740.1 - 0.52 9.9 6.5 0.93 9.1 6.5 1.3 1 0 0 1 1 1 0 BAR domain zf-C4H2 PF10146.9 EGC34740.1 - 3.3 8.0 5.4 5.7 7.2 5.4 1.4 1 0 0 1 1 1 0 Zinc finger-containing protein FA_hydroxylase PF04116.13 EGC34743.1 - 1.7e-22 80.2 22.2 1.7e-22 80.2 22.2 2.4 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily FNIP PF05725.12 EGC34744.1 - 6.2e-16 58.3 36.4 3.2e-05 24.0 4.6 6.4 3 1 3 7 7 7 6 FNIP Repeat zf-B_box PF00643.24 EGC34744.1 - 8.3e-07 29.1 6.0 1.5e-06 28.2 6.0 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC34744.1 - 0.015 15.4 2.0 0.03 14.5 2.0 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) AAA_3 PF07726.11 EGC34744.1 - 0.091 12.6 0.1 24 4.8 0.0 3.3 1 1 2 3 3 3 0 ATPase family associated with various cellular activities (AAA) DUF1644 PF07800.12 EGC34744.1 - 5.8 7.0 7.8 3.4 7.7 5.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) DUF5603 PF18231.1 EGC34745.1 - 0.015 15.6 2.3 0.018 15.3 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5603) Glyco_hydro_9 PF00759.19 EGC34746.1 - 5.6e-121 404.8 23.8 6.6e-121 404.6 23.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 TIR-like PF10137.9 EGC34747.1 - 8.4e-39 132.2 0.0 1.3e-38 131.5 0.0 1.3 1 0 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain TIR_2 PF13676.6 EGC34747.1 - 0.00013 22.6 0.0 0.00018 22.1 0.0 1.3 1 0 0 1 1 1 1 TIR domain DUF4062 PF13271.6 EGC34747.1 - 0.0034 17.7 0.0 0.0067 16.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) V_ATPase_I PF01496.19 EGC34747.1 - 0.0047 14.9 0.9 0.0058 14.6 0.9 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family TIR PF01582.20 EGC34747.1 - 0.028 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 TIR domain LMBR1 PF04791.16 EGC34747.1 - 0.55 9.1 3.3 0.61 8.9 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.9 EGC34747.1 - 5.2 5.5 7.7 5.5 5.4 7.7 1.2 1 0 0 1 1 1 0 Macoilin family HSP20 PF00011.21 EGC34748.1 - 2.7e-14 53.1 1.7 3.7e-06 27.0 0.1 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC34748.1 - 0.0046 16.5 0.1 0.067 12.8 0.0 2.2 2 0 0 2 2 2 1 HSP20-like domain found in ArsA Utp12 PF04003.12 EGC34749.1 - 8e-14 51.9 0.6 1.9e-13 50.7 0.6 1.7 1 0 0 1 1 1 1 Dip2/Utp12 Family ANAPC4_WD40 PF12894.7 EGC34749.1 - 0.00024 21.3 0.4 1.5 9.2 0.0 4.2 2 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain PQQ_2 PF13360.6 EGC34749.1 - 0.11 12.0 0.0 0.43 10.1 0.0 1.9 1 1 0 1 1 1 0 PQQ-like domain TT_ORF2 PF02957.15 EGC34749.1 - 2.5 9.0 5.9 5.3 8.0 5.9 1.6 1 0 0 1 1 1 0 TT viral ORF2 Myb_DNA-binding PF00249.31 EGC34750.1 - 4.4e-35 119.6 15.5 1.3e-14 54.0 0.2 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC34750.1 - 1.8e-30 105.0 11.6 9.4e-12 45.0 0.0 3.7 3 0 0 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGC34750.1 - 1.1e-08 35.1 11.5 6.8e-05 22.9 0.0 4.5 1 1 3 4 4 4 2 SLIDE Rap1_C PF11626.8 EGC34750.1 - 0.00048 20.2 0.1 0.53 10.4 0.0 3.2 1 1 1 3 3 3 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain HTH_32 PF13565.6 EGC34750.1 - 0.013 16.0 0.4 3.7 8.2 0.0 3.0 2 1 1 3 3 3 0 Homeodomain-like domain Myb_DNA-bind_2 PF08914.11 EGC34750.1 - 0.068 13.4 1.0 11 6.2 0.0 3.5 3 1 0 3 3 3 0 Rap1 Myb domain MADF_DNA_bdg PF10545.9 EGC34750.1 - 0.23 11.8 10.4 4.8 7.6 0.2 4.2 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Presenilin PF01080.17 EGC34750.1 - 3.9 6.1 8.7 5.6 5.6 8.7 1.2 1 0 0 1 1 1 0 Presenilin DUF3774 PF12609.8 EGC34750.1 - 8.4 7.5 8.2 3.9 8.5 0.0 3.3 3 1 0 3 3 3 0 Wound-induced protein MFS_1_like PF12832.7 EGC34751.1 - 1.3e-116 389.6 17.9 1.7e-116 389.3 17.9 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGC34751.1 - 2.1e-24 86.1 25.2 1.1e-21 77.2 16.0 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGC34751.1 - 4.6e-14 52.2 6.4 4.6e-14 52.2 6.4 2.3 2 1 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 EGC34751.1 - 0.0011 17.8 14.8 0.0011 17.8 14.8 2.1 2 0 0 2 2 2 2 LacY proton/sugar symporter AAA_22 PF13401.6 EGC34752.1 - 6.5e-05 23.2 0.0 0.72 10.1 0.0 4.5 4 0 0 4 4 4 2 AAA domain AAA PF00004.29 EGC34752.1 - 0.00091 19.7 3.8 0.024 15.1 0.0 4.3 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC34752.1 - 0.023 14.7 0.1 51 3.9 0.1 3.6 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC34752.1 - 1.7 9.0 4.4 14 6.1 0.0 4.0 3 0 0 3 3 3 0 AAA ATPase domain DUF3439 PF11921.8 EGC34752.1 - 3.4 7.6 9.6 10 6.1 9.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TIG PF01833.24 EGC34753.1 - 0.0004 20.4 0.4 0.00052 20.0 0.4 1.3 1 0 0 1 1 1 1 IPT/TIG domain DUF5111 PF17138.4 EGC34754.1 - 0.052 13.4 1.5 0.26 11.1 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5111) RapH_N PF18801.1 EGC34755.1 - 0.12 12.4 5.8 0.23 11.5 0.1 3.2 3 0 0 3 3 3 0 response regulator aspartate phosphatase H, N terminal DUF5409 PF17421.2 EGC34755.1 - 2 9.2 10.8 1.8 9.3 0.8 2.6 3 0 0 3 3 3 0 Family of unknown function (DUF5409) SLAC1 PF03595.17 EGC34756.1 - 0.047 12.9 4.6 0.09 12.0 4.6 1.6 1 1 0 1 1 1 0 Voltage-dependent anion channel RRM_1 PF00076.22 EGC34757.1 - 5.2e-26 90.3 7.4 1.5e-15 56.8 0.3 3.6 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC34757.1 - 9.4e-06 25.7 0.3 0.032 14.4 0.0 3.2 2 1 0 2 2 2 2 RNA recognition motif BRAP2 PF07576.12 EGC34757.1 - 0.0012 19.1 0.1 0.041 14.1 0.0 2.6 2 0 0 2 2 2 1 BRCA1-associated protein 2 SET_assoc PF11767.8 EGC34757.1 - 0.0067 16.1 0.1 0.048 13.3 0.0 2.4 2 0 0 2 2 2 1 Histone lysine methyltransferase SET associated RRM_5 PF13893.6 EGC34757.1 - 0.0078 15.8 0.9 0.24 11.0 0.0 3.3 2 2 1 3 3 3 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FNIP PF05725.12 EGC34758.1 - 4.4e-68 225.2 44.6 2.1e-13 50.2 0.4 8.9 4 2 6 11 11 11 10 FNIP Repeat DSPc PF00782.20 EGC34760.1 - 1.6e-24 86.2 0.2 5.3e-23 81.3 0.0 2.2 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC34760.1 - 0.00089 18.9 0.8 0.0024 17.5 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.12 EGC34760.1 - 0.025 14.9 0.0 0.062 13.6 0.0 1.7 1 0 0 1 1 1 0 Rit1 DUSP-like domain LRR_4 PF12799.7 EGC34761.1 - 6.3e-22 77.3 48.9 8.1e-06 26.1 6.1 6.5 4 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC34761.1 - 3.6e-21 75.4 25.2 5.7e-09 35.7 6.1 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_8 PF13855.6 EGC34761.1 - 3.9e-18 65.0 42.0 2.2e-06 27.3 4.7 4.7 3 1 1 4 4 4 4 Leucine rich repeat Cation_ATPase_C PF00689.21 EGC34763.1 - 1.1e-09 38.3 15.6 1.1e-09 38.3 15.6 3.5 3 1 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGC34763.1 - 0.11 12.7 0.0 1.1 9.5 0.0 2.2 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGC34763.1 - 0.25 10.8 0.0 0.25 10.8 0.0 3.6 4 0 0 4 4 4 0 E1-E2 ATPase DUF1772 PF08592.11 EGC34763.1 - 0.82 10.0 0.0 0.82 10.0 0.0 2.8 3 1 0 3 3 3 0 Domain of unknown function (DUF1772) FPL PF09758.9 EGC34764.1 - 4.4e-60 202.0 14.1 4.4e-60 202.0 14.1 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein SET PF00856.28 EGC34766.1 - 2.9e-08 34.3 24.0 6.1e-08 33.2 24.0 1.6 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGC34766.1 - 6.4e-06 26.2 10.2 6.4e-06 26.2 10.2 2.5 2 1 0 2 2 2 1 MYND finger SAF PF08666.12 EGC34766.1 - 0.019 15.6 0.0 1.2 9.8 0.0 2.3 2 0 0 2 2 2 0 SAF domain Ocular_alb PF02101.15 EGC34767.1 - 0.00032 19.7 9.2 0.0029 16.6 8.8 2.0 1 1 0 1 1 1 1 Ocular albinism type 1 protein DUF5305 PF17231.2 EGC34767.1 - 0.077 12.4 0.9 3.9 6.8 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF5305) DUF418 PF04235.12 EGC34767.1 - 0.11 12.4 0.2 0.11 12.4 0.2 2.6 3 1 0 3 3 3 0 Protein of unknown function (DUF418) PutA_N PF18083.1 EGC34767.1 - 0.13 12.3 0.1 0.24 11.4 0.1 1.4 1 0 0 1 1 1 0 Proline utilization A N-terminal domain PS_Dcarbxylase PF02666.15 EGC34769.1 - 0.061 12.9 3.9 0.11 12.0 0.0 2.1 1 1 1 2 2 2 0 Phosphatidylserine decarboxylase SAYSvFN PF10260.9 EGC34769.1 - 0.13 12.2 1.9 3.1 7.8 0.0 2.5 2 1 0 2 2 2 0 Uncharacterized conserved domain (SAYSvFN) DsbB PF02600.16 EGC34769.1 - 0.18 12.2 2.4 2.3 8.7 0.3 2.2 2 0 0 2 2 2 0 Disulfide bond formation protein DsbB UPF0029 PF01205.19 EGC34769.1 - 0.18 12.1 0.5 29 5.1 0.0 2.9 2 2 1 3 3 3 0 Uncharacterized protein family UPF0029 DUF3328 PF11807.8 EGC34769.1 - 0.78 9.5 7.1 2 8.1 1.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) DUF3899 PF13038.6 EGC34769.1 - 2.1 8.9 6.2 0.4 11.2 0.4 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF3899) DUF3446 PF11928.8 EGC34769.1 - 5.9 7.3 22.5 15 5.9 0.0 3.5 2 1 2 4 4 4 0 Early growth response N-terminal domain GST_C_3 PF14497.6 EGC34770.1 - 1.1e-09 38.3 0.1 2.4e-09 37.3 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC34770.1 - 1.7e-06 28.3 0.1 8.5e-06 26.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC34770.1 - 2e-06 27.9 0.0 3.3e-06 27.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF1836 PF08876.11 EGC34770.1 - 0.024 14.6 0.2 0.05 13.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1836) GST_C_2 PF13410.6 EGC34770.1 - 0.12 12.4 0.0 0.18 11.9 0.0 1.6 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Apis_Csd PF11671.8 EGC34770.1 - 3.1 7.8 8.4 1.4 8.9 5.9 1.7 2 0 0 2 2 2 0 Complementary sex determiner protein FGGY_N PF00370.21 EGC34771.1 - 3.5e-71 239.6 0.3 5.6e-71 239.0 0.3 1.3 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGC34771.1 - 2.9e-61 206.7 1.7 4.3e-61 206.1 0.4 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.20 EGC34771.1 - 0.066 12.7 0.0 1.1 8.7 0.0 2.2 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PH_3 PF14593.6 EGC34772.1 - 2.9e-20 72.3 0.0 5.3e-20 71.5 0.0 1.4 1 0 0 1 1 1 1 PH domain PH PF00169.29 EGC34772.1 - 2.1e-07 31.4 1.8 3.8e-07 30.6 0.2 2.0 2 0 0 2 2 2 1 PH domain Androgen_recep PF02166.16 EGC34772.1 - 0.084 11.7 4.2 0.11 11.3 4.2 1.1 1 0 0 1 1 1 0 Androgen receptor TERB2 PF15101.6 EGC34772.1 - 0.21 11.6 3.7 0.29 11.2 3.7 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Exonuc_VII_L PF02601.15 EGC34772.1 - 1.6 8.2 7.8 2.2 7.8 7.8 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit Na_Ca_ex_C PF16494.5 EGC34772.1 - 2.1 8.8 9.9 5.3 7.5 3.5 2.4 1 1 1 2 2 2 0 C-terminal extension of sodium/calcium exchanger domain AAA_23 PF13476.6 EGC34773.1 - 2.5e-16 60.8 24.7 2.5e-16 60.8 24.7 4.9 2 1 2 4 4 4 1 AAA domain Metallophos PF00149.28 EGC34773.1 - 4.1e-06 27.4 0.1 4.1e-06 27.4 0.1 2.8 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase AAA_29 PF13555.6 EGC34773.1 - 0.00018 21.1 0.0 0.00045 19.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGC34773.1 - 0.0003 20.3 38.3 0.00064 19.2 2.7 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.6 EGC34773.1 - 0.045 14.1 0.3 2.7 8.3 0.0 2.9 2 1 1 3 3 3 0 AAA ATPase domain Acetyltransf_18 PF18014.1 EGC34773.1 - 2.8 7.8 4.6 3.2 7.6 0.2 3.1 2 1 2 4 4 4 0 Acetyltransferase (GNAT) domain SlyX PF04102.12 EGC34773.1 - 4.2 8.1 13.7 4.9 7.8 0.7 4.1 2 1 1 3 3 3 0 SlyX FNIP PF05725.12 EGC34774.1 - 2e-37 127.1 38.5 1.1e-12 47.9 4.1 7.1 5 2 1 6 6 6 5 FNIP Repeat Laminin_EGF PF00053.24 EGC34775.1 - 0.45 10.7 27.6 0.79 9.9 11.5 2.9 2 1 1 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC34775.1 - 6.9 7.1 20.7 4.6 7.7 2.7 3.1 2 0 0 2 2 2 0 EGF-like domain HECT PF00632.25 EGC34776.1 - 5.2e-90 302.0 1.9 7.2e-90 301.6 0.8 1.8 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) AZUL PF16558.5 EGC34776.1 - 7.3e-14 51.7 1.1 1.3e-13 50.9 1.1 1.5 1 0 0 1 1 1 1 Amino-terminal Zinc-binding domain of ubiquitin ligase E3A Suf PF05843.14 EGC34777.1 - 0.00081 19.5 0.7 0.00081 19.5 0.7 5.3 2 1 3 5 5 5 3 Suppressor of forked protein (Suf) S1 PF00575.23 EGC34777.1 - 0.003 17.9 0.0 0.003 17.9 0.0 4.3 4 1 0 4 4 4 1 S1 RNA binding domain TPR_17 PF13431.6 EGC34777.1 - 0.015 15.6 0.0 16 6.1 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC34777.1 - 0.041 14.5 0.0 0.21 12.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF370 PF04025.12 EGC34777.1 - 0.077 13.1 0.0 2.8 8.1 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF370) TPR_14 PF13428.6 EGC34777.1 - 0.088 13.7 0.0 40 5.4 0.0 3.5 3 1 1 4 4 4 0 Tetratricopeptide repeat EMP70 PF02990.16 EGC34778.1 - 8.4e-121 404.2 23.5 8.4e-121 404.2 23.5 1.4 2 0 0 2 2 2 1 Endomembrane protein 70 FNIP PF05725.12 EGC34779.1 - 3.3e-18 65.6 16.8 0.00013 22.1 1.2 6.3 4 3 1 6 6 6 4 FNIP Repeat zf-C3HC4_2 PF13923.6 EGC34779.1 - 0.0003 20.5 14.1 0.0003 20.5 14.1 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC34779.1 - 0.00033 20.5 11.6 0.00033 20.5 11.6 2.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC34779.1 - 0.0019 18.5 13.4 0.0019 18.5 13.4 2.5 2 1 0 2 2 2 1 Ring finger domain zf-Di19 PF05605.12 EGC34779.1 - 0.0076 16.5 1.3 0.0076 16.5 1.3 3.0 3 1 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-TRAF PF02176.18 EGC34779.1 - 0.022 15.4 2.6 0.022 15.4 2.6 3.3 3 1 0 3 3 1 0 TRAF-type zinc finger ParBc_2 PF08857.11 EGC34779.1 - 0.025 14.7 0.1 6.7 6.8 0.0 3.1 3 1 0 3 3 3 0 Putative ParB-like nuclease U-box PF04564.15 EGC34779.1 - 0.1 12.8 0.1 1.4 9.2 0.0 2.8 1 1 1 2 2 2 0 U-box domain zf-ACC PF17848.1 EGC34779.1 - 0.15 12.2 6.3 1.4 9.1 0.3 3.9 3 0 0 3 3 3 0 Acetyl-coA carboxylase zinc finger domain zf-Nse PF11789.8 EGC34779.1 - 0.63 9.9 9.3 2.7 7.9 9.3 2.1 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGC34779.1 - 0.85 9.5 19.4 0.034 14.0 12.1 2.3 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC34779.1 - 1.4 8.9 19.8 0.37 10.7 15.8 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Pro-kuma_activ PF09286.11 EGC34780.1 - 3.5e-30 105.2 0.5 8.2e-30 104.0 0.5 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC34780.1 - 4.1e-06 26.3 1.1 9.9e-06 25.0 1.1 1.5 1 0 0 1 1 1 1 Subtilase family UXS1_N PF11803.8 EGC34780.1 - 0.09 13.2 0.1 26 5.3 0.0 3.4 3 0 0 3 3 3 0 UDP-glucuronate decarboxylase N-terminal CBM49 PF09478.10 EGC34781.1 - 5.7e-13 49.0 3.2 5.7e-13 49.0 3.2 2.0 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 DNA_pol3_beta PF00712.19 EGC34781.1 - 0.14 12.2 2.9 0.19 11.9 0.6 2.3 2 1 1 3 3 3 0 DNA polymerase III beta subunit, N-terminal domain DUF3689 PF12463.8 EGC34782.1 - 1.8e-27 96.5 6.2 7.9e-27 94.4 6.2 2.2 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) CENP-B_dimeris PF09026.10 EGC34782.1 - 0.0062 16.9 1.9 4.7 7.7 0.4 2.7 2 0 0 2 2 2 2 Centromere protein B dimerisation domain MID_MedPIWI PF18296.1 EGC34782.1 - 0.021 14.6 1.6 4.1 7.1 0.1 2.3 2 0 0 2 2 2 0 MID domain of medPIWI FAM60A PF15396.6 EGC34782.1 - 4.8 7.1 7.0 2.2 8.2 0.6 2.3 2 0 0 2 2 2 0 Protein Family FAM60A TM2 PF05154.16 EGC34783.1 - 2.3e-18 66.2 8.6 3.3e-18 65.7 8.6 1.2 1 0 0 1 1 1 1 TM2 domain GDI PF00996.18 EGC34784.1 - 1.8e-50 171.8 4.8 5.1e-47 160.4 2.6 2.1 2 0 0 2 2 2 2 GDP dissociation inhibitor tRNA-synt_1c PF00749.21 EGC34784.1 - 0.32 9.9 6.3 0.55 9.1 6.3 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain FNIP PF05725.12 EGC34785.1 - 1.5e-155 505.2 49.3 2.3e-15 56.4 0.2 12.2 12 0 0 12 12 12 12 FNIP Repeat Phage_min_tail PF05939.13 EGC34785.1 - 4.2e-06 27.1 0.1 53 4.2 0.0 7.5 4 2 4 8 8 8 1 Phage minor tail protein DUF3760 PF12586.8 EGC34785.1 - 6.7 7.0 9.9 0.36 11.1 0.1 4.0 5 1 1 6 6 6 0 Protein of unknown function (DUF3760) Rhomboid PF01694.22 EGC34786.1 - 1.4e-16 60.8 11.5 2.4e-16 60.1 11.5 1.3 1 0 0 1 1 1 1 Rhomboid family DER1 PF04511.15 EGC34786.1 - 4.6e-06 26.7 19.3 1.5e-05 25.0 19.3 1.7 1 1 0 1 1 1 1 Der1-like family SUIM_assoc PF16619.5 EGC34786.1 - 0.0073 16.3 9.3 0.012 15.6 9.3 1.4 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF1751 PF08551.10 EGC34786.1 - 0.026 15.1 4.2 0.026 15.1 4.2 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) Androgen_recep PF02166.16 EGC34786.1 - 0.072 11.9 13.7 0.096 11.5 13.7 1.1 1 0 0 1 1 1 0 Androgen receptor tRNA_bind PF01588.20 EGC34787.1 - 4.2e-20 71.7 0.3 6.7e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 Putative tRNA binding domain Myosin_head PF00063.21 EGC34788.1 - 6e-282 936.9 5.2 7.7e-282 936.5 5.2 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC34788.1 - 3.6e-43 147.4 4.6 3.7e-43 147.4 3.1 1.8 2 0 0 2 2 2 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGC34788.1 - 2.9e-15 55.6 0.0 6e-15 54.6 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC34788.1 - 4.3e-15 55.3 0.0 1e-14 54.1 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC34788.1 - 3.3e-11 42.7 0.0 7.7e-11 41.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_16 PF13191.6 EGC34788.1 - 0.0018 18.7 0.0 0.0041 17.5 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain Hpr_kinase_C PF07475.12 EGC34788.1 - 0.052 13.1 0.5 3.9 7.0 0.1 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.27 EGC34788.1 - 0.079 13.5 0.2 0.26 11.8 0.2 1.9 1 1 0 1 1 1 0 ABC transporter Zeta_toxin PF06414.12 EGC34788.1 - 0.089 12.1 0.0 0.24 10.7 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_22 PF13401.6 EGC34788.1 - 0.12 12.6 0.1 0.51 10.6 0.1 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC34788.1 - 0.15 12.6 0.0 0.46 11.0 0.0 1.8 1 0 0 1 1 1 0 AAA domain SICA_C PF12879.7 EGC34789.1 - 0.027 14.5 0.2 0.059 13.4 0.2 1.5 1 0 0 1 1 1 0 SICA C-terminal inner membrane domain ArfGap PF01412.18 EGC34791.1 - 4e-44 149.5 0.5 4.8e-44 149.2 0.5 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA-synt_2d PF01409.20 EGC34791.1 - 0.053 13.0 0.0 0.068 12.7 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Pkinase PF00069.25 EGC34792.1 - 5.6e-54 183.3 0.3 1.6e-40 139.1 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC34792.1 - 2.5e-29 102.4 0.0 1.1e-22 80.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC34792.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGC34792.1 - 0.013 15.2 0.3 0.88 9.1 0.1 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Kdo PF06293.14 EGC34792.1 - 0.032 13.6 0.0 0.071 12.5 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family A_deaminase PF00962.22 EGC34793.1 - 1.8e-26 93.3 0.0 3e-26 92.5 0.0 1.4 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.11 EGC34793.1 - 1.4e-13 50.9 1.1 4.2e-13 49.4 1.1 1.9 1 1 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Spore_III_AF PF09581.10 EGC34794.1 - 0.093 12.7 4.7 0.15 12.1 4.7 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) CbiK PF06180.11 EGC34796.1 - 0.0042 16.4 0.1 0.012 14.9 0.1 1.8 1 1 0 1 1 1 1 Cobalt chelatase (CbiK) DUF2303 PF10065.9 EGC34796.1 - 0.069 12.3 0.0 0.12 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2303) YmgD PF16456.5 EGC34796.1 - 0.16 12.0 0.0 0.47 10.5 0.0 1.7 1 0 0 1 1 1 0 YmgD protein Striatin PF08232.12 EGC34798.1 - 1.4 9.5 8.2 5.8 7.5 4.4 2.3 2 0 0 2 2 2 0 Striatin family Menin PF05053.13 EGC34798.1 - 1.8 6.8 13.6 1 7.6 10.3 1.8 2 0 0 2 2 2 0 Menin Folate_carrier PF01770.18 EGC34798.1 - 2.6 6.7 5.1 3.6 6.2 5.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Apc15p PF05841.11 EGC34798.1 - 3.1 8.6 19.4 2.4 9.0 13.3 2.9 3 0 0 3 3 3 0 Apc15p protein RNA_pol_Rbc25 PF08292.12 EGC34798.1 - 7.4 6.8 7.2 1.1 9.5 2.1 2.3 3 0 0 3 3 3 0 RNA polymerase III subunit Rpc25 Glyco_trans_2_3 PF13632.6 EGC34799.1 - 7.4e-22 78.2 0.1 7.4e-22 78.2 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.14 EGC34799.1 - 1.4e-18 66.9 23.5 7.9e-13 47.8 1.8 4.4 4 1 1 5 5 5 4 Cellulose synthase Glyco_tranf_2_3 PF13641.6 EGC34799.1 - 6.4e-15 55.7 0.0 1.8e-14 54.2 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.26 EGC34799.1 - 2.3e-11 43.8 0.0 1.1e-09 38.3 0.0 2.7 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.6 EGC34799.1 - 2.3e-07 30.5 0.0 3.6e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase family 21 EMC3_TMCO1 PF01956.16 EGC34799.1 - 0.017 14.9 5.9 0.021 14.6 0.9 2.4 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like SPASM PF13186.6 EGC34799.1 - 0.12 12.9 0.1 37 4.9 0.0 2.7 2 0 0 2 2 2 0 Iron-sulfur cluster-binding domain UBX PF00789.20 EGC34800.1 - 5.4e-11 42.6 0.0 1.1e-10 41.5 0.0 1.6 1 0 0 1 1 1 1 UBX domain Abhydro_lipase PF04083.16 EGC34801.1 - 5.6e-20 70.7 0.1 2.6e-19 68.5 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC34801.1 - 1.1e-12 48.2 1.0 5e-12 46.0 1.0 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34801.1 - 0.011 15.0 0.0 0.026 13.8 0.0 1.6 2 0 0 2 2 2 0 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGC34801.1 - 0.25 10.2 0.6 1.7 7.5 0.1 2.6 3 1 0 3 3 3 0 Chlorophyllase enzyme Abhydro_lipase PF04083.16 EGC34803.1 - 9.6e-17 60.3 0.0 5e-16 58.0 0.0 2.1 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC34803.1 - 3.6e-15 56.3 0.4 8.4e-10 38.7 0.0 2.1 2 0 0 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34803.1 - 2e-10 40.4 0.0 7.3e-08 32.0 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGC34803.1 - 0.0053 15.7 0.0 0.0088 15.0 0.0 1.4 1 0 0 1 1 1 1 Chlorophyllase enzyme Abhydro_lipase PF04083.16 EGC34804.1 - 7.7e-17 60.6 0.0 4.9e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC34804.1 - 1.4e-16 60.9 1.3 3.3e-15 56.4 1.3 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC34804.1 - 1.3e-11 44.3 0.0 1.1e-07 31.4 0.0 2.2 2 0 0 2 2 2 2 Serine aminopeptidase, S33 FSH1 PF03959.13 EGC34804.1 - 0.018 14.7 0.0 0.082 12.6 0.0 1.8 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DLH PF01738.18 EGC34804.1 - 0.028 14.0 0.0 3 7.3 0.0 2.6 3 0 0 3 3 3 0 Dienelactone hydrolase family Dicty_CTDC PF00526.18 EGC34805.1 - 1.1e-06 28.4 21.8 0.00012 21.8 5.2 12.2 11 4 2 13 13 13 7 Dictyostelium (slime mold) repeat Methyltransf_4 PF02390.17 EGC34806.1 - 1e-25 90.2 0.0 1e-25 90.2 0.0 3.2 3 1 1 4 4 4 1 Putative methyltransferase PPR_2 PF13041.6 EGC34806.1 - 6.4e-15 55.1 3.3 1.3e-05 25.3 0.0 3.8 2 1 2 4 4 4 4 PPR repeat family PPR PF01535.20 EGC34806.1 - 5.2e-09 35.7 1.7 0.003 17.7 0.0 4.1 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.6 EGC34806.1 - 2.1e-08 34.1 3.4 0.0013 18.8 0.1 3.2 2 1 1 3 3 3 3 Pentatricopeptide repeat domain PPR_long PF17177.4 EGC34806.1 - 2e-06 27.3 0.3 4.8e-06 26.1 0.3 1.6 1 0 0 1 1 1 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGC34806.1 - 2.9e-05 23.7 0.8 0.12 12.1 0.0 3.4 3 0 0 3 3 3 2 PPR repeat WDCP PF15390.6 EGC34806.1 - 1 7.7 13.6 1.9 6.8 13.6 1.4 1 0 0 1 1 1 0 WD repeat and coiled-coil-containing protein family Presenilin PF01080.17 EGC34806.1 - 1.4 7.6 21.8 2.2 7.0 21.8 1.2 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGC34806.1 - 1.7 7.3 11.8 2.5 6.7 11.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF974 PF06159.13 EGC34807.1 - 3.8e-53 180.8 0.0 3.8e-53 180.8 0.0 2.4 2 1 1 3 3 3 1 Protein of unknown function (DUF974) Transglut_C PF00927.22 EGC34807.1 - 0.00015 21.9 0.5 0.015 15.5 0.1 2.9 2 0 0 2 2 2 1 Transglutaminase family, C-terminal ig like domain TFIIA PF03153.13 EGC34807.1 - 0.0052 16.8 19.0 0.0092 16.0 19.0 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Pox_P35 PF03213.14 EGC34807.1 - 0.011 14.9 1.9 0.3 10.2 1.2 2.2 2 0 0 2 2 2 0 Poxvirus P35 protein Maf1 PF09174.10 EGC34807.1 - 0.12 12.5 0.2 0.12 12.5 0.2 2.3 2 0 0 2 2 2 0 Maf1 regulator Presenilin PF01080.17 EGC34807.1 - 1 8.1 3.4 1.5 7.5 3.4 1.2 1 0 0 1 1 1 0 Presenilin DUF3371 PF11851.8 EGC34807.1 - 1.6 9.9 12.4 4.2 8.5 12.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF4834 PF16118.5 EGC34807.1 - 2.3 9.2 11.3 0.68 10.9 7.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Pex14_N PF04695.13 EGC34807.1 - 4.6 7.9 19.8 12 6.5 19.8 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MMR1 PF08505.10 EGC34807.1 - 4.9 7.4 15.7 2.2 8.5 8.1 2.3 2 0 0 2 2 2 0 Mitochondrial Myo2 receptor-related protein Hydrolase_4 PF12146.8 EGC34809.1 - 6.9e-49 166.3 0.0 7.8e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC34809.1 - 1.4e-09 38.9 0.0 1.6e-09 38.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.20 EGC34809.1 - 3e-08 33.6 0.0 3.3e-08 33.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.20 EGC34809.1 - 0.0017 18.0 0.0 0.0026 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.16 EGC34809.1 - 0.026 14.4 0.0 3.6 7.3 0.0 2.2 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Thioesterase PF00975.20 EGC34809.1 - 0.12 12.4 0.0 0.17 12.0 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain Abhydrolase_3 PF07859.13 EGC34809.1 - 0.17 11.7 0.0 0.21 11.4 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-CCHC PF00098.23 EGC34810.1 - 1.9e-06 27.7 1.3 2.9e-06 27.1 1.3 1.3 1 0 0 1 1 1 1 Zinc knuckle DUF1825 PF08855.10 EGC34810.1 - 0.017 15.0 1.6 0.1 12.5 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) Macoilin PF09726.9 EGC34810.1 - 8.2 4.9 24.0 2.2 6.7 18.4 2.0 2 0 0 2 2 2 0 Macoilin family c-SKI_SMAD_bind PF08782.10 EGC34812.1 - 0.64 10.3 5.1 0.22 11.8 2.4 1.7 1 1 0 1 1 1 0 c-SKI Smad4 binding domain SurA_N_2 PF13623.6 EGC34812.1 - 2.7 7.8 13.9 2.3 8.1 0.0 2.0 1 1 1 2 2 2 0 SurA N-terminal domain G8 PF10162.9 EGC34813.1 - 1.2e-27 96.4 0.1 2.8e-27 95.2 0.1 1.7 1 0 0 1 1 1 1 G8 domain RRM_1 PF00076.22 EGC34814.1 - 1.7e-55 184.7 3.8 8e-21 73.6 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC34814.1 - 1.4e-07 31.1 1.7 0.0087 15.7 0.3 2.8 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC34814.1 - 2.6e-05 24.3 4.1 0.031 14.4 0.0 4.2 4 2 0 4 4 4 1 RNA recognition motif PHM7_cyt PF14703.6 EGC34814.1 - 7.1e-05 23.1 3.5 3.1 8.0 0.0 4.9 3 3 3 6 6 6 2 Cytosolic domain of 10TM putative phosphate transporter RNA_bind PF08675.11 EGC34814.1 - 0.00071 19.6 0.0 2.2 8.4 0.0 3.2 3 1 0 3 3 3 2 RNA binding domain RRM_Rrp7 PF17799.1 EGC34814.1 - 0.018 14.9 1.1 0.73 9.6 0.1 3.0 2 1 0 2 2 2 0 Rrp7 RRM-like N-terminal domain RRM_occluded PF16842.5 EGC34814.1 - 0.038 13.8 0.0 2.3 8.1 0.0 3.0 3 0 0 3 3 3 0 Occluded RNA-recognition motif DUF2464 PF10240.9 EGC34814.1 - 0.048 13.2 0.5 0.26 10.8 0.0 2.4 3 0 0 3 3 3 0 Multivesicular body subunit 12 Limkain-b1 PF11608.8 EGC34814.1 - 0.062 13.4 0.2 24 5.1 0.0 3.1 3 0 0 3 3 3 0 Limkain b1 UBX PF00789.20 EGC34815.1 - 7.3e-13 48.5 0.0 2.2e-12 47.0 0.0 1.8 1 0 0 1 1 1 1 UBX domain Comm PF15957.5 EGC34815.1 - 0.12 12.8 0.0 0.28 11.6 0.0 1.7 2 0 0 2 2 2 0 Commissureless Terminase_6C PF17289.2 EGC34815.1 - 0.12 12.4 0.8 0.21 11.7 0.8 1.5 1 0 0 1 1 1 0 Terminase RNaseH-like domain Folate_carrier PF01770.18 EGC34815.1 - 0.13 11.0 0.5 0.48 9.1 0.1 1.8 2 0 0 2 2 2 0 Reduced folate carrier Peptidase_S46 PF10459.9 EGC34815.1 - 0.29 9.7 7.5 0.34 9.5 7.5 1.1 1 0 0 1 1 1 0 Peptidase S46 Lipoprotein_3 PF00938.17 EGC34815.1 - 0.43 10.8 5.3 5.6 7.2 0.8 2.6 2 0 0 2 2 2 0 Lipoprotein OAD_gamma PF04277.13 EGC34815.1 - 1.5 9.4 3.2 1.8 9.2 0.2 2.4 2 1 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain MAP17 PF15807.5 EGC34815.1 - 2.4 8.4 10.8 0.32 11.2 0.4 2.2 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Proteasome PF00227.26 EGC34816.1 - 1e-40 139.3 0.0 1.2e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Chromo PF00385.24 EGC34817.1 - 1.4e-07 31.3 0.9 4.2e-07 29.8 0.9 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve_3 PF13683.6 EGC34817.1 - 0.00021 21.0 0.3 0.00087 19.0 0.0 2.1 2 1 0 2 2 2 1 Integrase core domain rve PF00665.26 EGC34817.1 - 0.013 15.6 0.0 0.023 14.9 0.0 1.4 1 0 0 1 1 1 0 Integrase core domain Hce2 PF14856.6 EGC34817.1 - 0.064 13.5 0.6 5.1 7.4 0.1 2.6 2 1 1 3 3 3 0 Pathogen effector; putative necrosis-inducing factor Tudor-knot PF11717.8 EGC34817.1 - 0.18 11.7 2.3 0.4 10.6 2.3 1.7 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain SelK_SelG PF10961.8 EGC34820.1 - 3e-12 47.0 38.6 1.1e-10 42.0 38.6 2.5 1 1 0 1 1 1 1 Selenoprotein SelK_SelG ASFV_L11L PF05293.11 EGC34820.1 - 0.032 14.5 0.1 0.044 14.1 0.1 1.1 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein LSM PF01423.22 EGC34821.1 - 1.5e-19 69.4 0.0 1.7e-19 69.2 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC34821.1 - 0.019 15.1 0.0 0.024 14.7 0.0 1.1 1 0 0 1 1 1 0 Ataxin 2 SM domain mRNA_decap_C PF16741.5 EGC34821.1 - 0.019 14.2 0.0 0.034 13.4 0.0 1.3 1 0 0 1 1 1 0 mRNA-decapping enzyme C-terminus LSM14 PF12701.7 EGC34821.1 - 0.12 12.5 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Scd6-like Sm domain AAA_11 PF13086.6 EGC34822.1 - 0.29 10.9 9.9 0.36 10.6 9.9 1.2 1 0 0 1 1 1 0 AAA domain Exonuc_VII_L PF02601.15 EGC34822.1 - 1.7 8.1 8.4 2.1 7.8 8.4 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Transketolase_N PF00456.21 EGC34822.1 - 8.9 5.2 6.7 13 4.6 6.7 1.2 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain NIF PF03031.18 EGC34823.1 - 4.2e-10 39.6 0.1 5e-10 39.4 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase FNIP PF05725.12 EGC34824.1 - 3.2e-52 174.4 63.0 2.4e-12 46.8 1.8 9.6 4 3 6 11 11 11 10 FNIP Repeat DDE_3 PF13358.6 EGC34827.1 - 5.9e-11 42.3 0.2 7.3e-11 42.0 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Peptidase_M1 PF01433.20 EGC34828.1 - 2.3e-10 40.4 0.2 2.3e-10 40.4 0.2 2.3 2 0 0 2 2 2 1 Peptidase family M1 domain Peptidase_M1_N PF17900.1 EGC34828.1 - 6.8e-07 29.7 1.3 6.8e-07 29.7 1.3 3.6 3 1 0 3 3 3 1 Peptidase M1 N-terminal domain VacA2 PF03077.14 EGC34828.1 - 3.7 7.5 6.9 9.9 6.1 6.9 1.6 1 0 0 1 1 1 0 Putative vacuolating cytotoxin ELM2 PF01448.24 EGC34832.1 - 0.0024 18.6 0.2 0.0024 18.6 0.2 4.1 3 1 0 3 3 3 1 ELM2 domain EF-hand_6 PF13405.6 EGC34833.1 - 9.3e-12 43.9 0.0 0.0019 18.0 0.0 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_1 PF00036.32 EGC34833.1 - 3.4e-11 41.9 0.0 0.00041 19.7 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_5 PF13202.6 EGC34833.1 - 6.8e-11 41.2 0.0 2.1e-05 23.8 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_7 PF13499.6 EGC34833.1 - 5.6e-10 39.5 0.0 4e-06 27.2 0.0 3.1 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC34833.1 - 0.00034 20.4 0.0 0.0064 16.3 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair Dockerin_1 PF00404.18 EGC34833.1 - 0.032 14.4 0.0 24 5.2 0.0 2.6 1 1 1 3 3 3 0 Dockerin type I domain GAPT PF11770.8 EGC34835.1 - 0.0025 17.7 0.7 0.0029 17.5 0.7 1.1 1 0 0 1 1 1 1 GRB2-binding adapter (GAPT) ResIII PF04851.15 EGC34835.1 - 0.062 13.3 0.3 0.078 13.0 0.3 1.1 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit zf-RVT PF13966.6 EGC34836.1 - 0.00019 22.0 0.7 0.00024 21.7 0.6 1.3 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase ATP-synt_F6 PF05511.11 EGC34837.1 - 0.1 13.0 0.1 0.26 11.7 0.1 1.6 1 0 0 1 1 1 0 Mitochondrial ATP synthase coupling factor 6 FNIP PF05725.12 EGC34838.1 - 2.1e-17 63.0 48.5 1.3e-09 38.1 1.5 9.4 5 4 4 9 9 9 8 FNIP Repeat ATF7IP_BD PF16788.5 EGC34839.1 - 3.8 7.5 17.1 7.7 6.6 17.1 1.5 1 0 0 1 1 1 0 ATF-interacting protein binding domain IBN_N PF03810.19 EGC34840.1 - 2.7e-06 27.2 0.4 1.8e-05 24.6 0.4 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain BetaGal_dom4_5 PF13364.6 EGC34840.1 - 0.034 14.7 0.5 0.078 13.6 0.5 1.5 1 0 0 1 1 1 0 Beta-galactosidase jelly roll domain Urb2 PF10441.9 EGC34840.1 - 3.5 7.5 6.1 4 7.3 0.4 3.3 3 0 0 3 3 3 0 Urb2/Npa2 family MCM PF00493.23 EGC34841.1 - 6.8e-72 241.2 0.1 1.3e-71 240.3 0.1 1.4 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGC34841.1 - 4.2e-19 68.6 0.3 1.1e-18 67.2 0.3 1.7 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC34841.1 - 9.3e-19 67.7 1.0 9.3e-19 67.7 1.0 3.0 3 0 0 3 3 3 1 MCM AAA-lid domain AAA_5 PF07728.14 EGC34841.1 - 2.8e-07 30.6 0.0 6.6e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGC34841.1 - 2.5e-06 27.0 0.1 0.0031 16.9 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.11 EGC34841.1 - 0.0035 17.2 0.0 0.0091 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGC34841.1 - 0.0046 16.7 1.2 0.015 15.1 1.2 1.8 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGC34841.1 - 0.01 16.3 0.2 0.01 16.3 0.2 2.5 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC34841.1 - 0.14 12.5 0.1 0.14 12.5 0.1 2.9 3 1 0 3 3 3 0 AAA ATPase domain Alpha_kinase PF02816.18 EGC34842.1 - 4.2e-49 167.2 2.6 4.2e-49 167.2 2.6 1.7 2 0 0 2 2 2 1 Alpha-kinase family VWA_2 PF13519.6 EGC34842.1 - 0.0014 19.3 0.0 0.0039 17.8 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain Alpha_kinase PF02816.18 EGC34843.1 - 7.7e-42 143.5 0.2 1.3e-41 142.7 0.2 1.4 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.6 EGC34843.1 - 0.00079 20.0 0.0 0.0019 18.8 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Peptidase_C39_2 PF13529.6 EGC34843.1 - 0.14 12.7 0.1 2.9 8.4 0.1 2.5 1 1 1 2 2 2 0 Peptidase_C39 like family TACC_C PF05010.14 EGC34845.1 - 0.0019 18.0 13.0 0.0046 16.8 13.0 1.5 1 1 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Glyco_transf_41 PF13844.6 EGC34845.1 - 0.014 13.9 1.5 0.017 13.6 1.5 1.2 1 0 0 1 1 1 0 Glycosyl transferase family 41 Transglut_core PF01841.19 EGC34846.1 - 7e-13 49.0 0.0 1.4e-12 48.0 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily ER PF01133.17 EGC34846.1 - 0.042 13.9 4.1 0.52 10.4 0.1 3.6 3 1 1 4 4 4 0 Enhancer of rudimentary RecG_N PF17190.4 EGC34846.1 - 0.93 10.3 7.5 17 6.2 0.3 3.6 2 1 1 3 3 3 0 RecG N-terminal helical domain CLN3 PF02487.17 EGC34846.1 - 1.1 8.2 5.5 2.1 7.3 5.5 1.4 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 EGC34846.1 - 2.9 6.6 9.4 6.7 5.4 9.4 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter RP-C_C PF11800.8 EGC34846.1 - 3.2 7.8 5.8 9.5 6.3 5.8 1.8 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C39_2 PF13529.6 EGC34847.1 - 2.9e-12 47.3 0.0 1.1e-10 42.3 0.0 2.1 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.15 EGC34847.1 - 0.0082 16.0 0.1 0.042 13.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase C39 family Adenine_glyco PF03352.13 EGC34848.1 - 3.2e-66 222.4 0.1 3.6e-66 222.3 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase zf-HC5HC2H PF13771.6 EGC34849.1 - 3.7 7.9 6.8 0.16 12.2 0.6 2.0 2 0 0 2 2 2 0 PHD-like zinc-binding domain Peptidase_S8 PF00082.22 EGC34850.1 - 6e-37 127.5 0.1 9.5e-37 126.9 0.1 1.3 1 0 0 1 1 1 1 Subtilase family DUF4303 PF14136.6 EGC34850.1 - 0.054 13.3 0.1 0.17 11.6 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4303) Rhabdo_matrix PF03397.14 EGC34850.1 - 0.093 12.5 0.1 0.29 10.9 0.0 1.8 2 0 0 2 2 2 0 Rhabdovirus matrix protein Sugar_transport PF06800.12 EGC34850.1 - 0.16 11.3 0.2 0.27 10.5 0.2 1.3 1 0 0 1 1 1 0 Sugar transport protein EGF_Tenascin PF18720.1 EGC34850.1 - 0.21 11.6 9.5 0.6 10.2 9.5 1.8 1 0 0 1 1 1 0 Tenascin EGF domain Atx10homo_assoc PF09759.9 EGC34850.1 - 2.5 8.2 7.8 2 8.5 2.9 2.5 2 0 0 2 2 2 0 Spinocerebellar ataxia type 10 protein domain EGF_2 PF07974.13 EGC34850.1 - 3.5 8.1 14.8 7.9 6.9 14.8 1.6 1 0 0 1 1 1 0 EGF-like domain Peptidase_S8 PF00082.22 EGC34851.1 - 4.6e-36 124.6 0.6 7.6e-36 123.9 0.6 1.3 1 0 0 1 1 1 1 Subtilase family hEGF PF12661.7 EGC34851.1 - 0.0036 17.9 6.9 0.0036 17.9 6.9 3.1 2 0 0 2 2 2 1 Human growth factor-like EGF EGF PF00008.27 EGC34851.1 - 0.016 15.5 10.2 0.016 15.5 10.2 2.4 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.13 EGC34851.1 - 0.022 15.1 11.1 0.022 15.1 11.1 2.5 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 EGC34851.1 - 0.21 11.7 8.1 0.47 10.6 8.1 1.6 1 0 0 1 1 1 0 Tenascin EGF domain ABC_membrane PF00664.23 EGC34852.1 - 7.8e-70 235.6 37.7 4e-40 138.2 16.3 2.6 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC34852.1 - 1e-48 165.3 0.9 7.3e-29 101.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.19 EGC34852.1 - 1.7e-09 37.4 0.2 0.021 14.2 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGC34852.1 - 4.8e-07 29.8 0.0 0.0046 16.7 0.0 3.3 3 1 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.6 EGC34852.1 - 2.6e-05 23.9 2.4 0.012 15.3 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.12 EGC34852.1 - 4.6e-05 22.8 0.3 0.077 12.3 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin RsgA_GTPase PF03193.16 EGC34852.1 - 0.00013 22.0 0.6 0.006 16.5 0.1 2.5 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGC34852.1 - 0.00015 21.8 0.4 0.48 10.5 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGC34852.1 - 0.00043 20.2 2.5 0.048 13.5 0.0 3.6 4 0 0 4 4 4 1 AAA domain, putative AbiEii toxin, Type IV TA system TrwB_AAD_bind PF10412.9 EGC34852.1 - 0.0025 16.8 0.2 1.1 8.1 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EGC34852.1 - 0.004 17.5 0.0 0.55 10.6 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC34852.1 - 0.011 16.0 0.8 1.7 9.0 0.1 3.1 2 1 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGC34852.1 - 0.021 14.9 0.4 0.021 14.9 0.4 2.8 3 0 0 3 3 2 0 Dynamin family AAA_7 PF12775.7 EGC34852.1 - 0.042 13.4 0.2 2.7 7.5 0.1 2.4 2 0 0 2 2 2 0 P-loop containing dynein motor region Roc PF08477.13 EGC34852.1 - 0.12 12.6 1.3 21 5.4 0.0 3.6 4 0 0 4 4 3 0 Ras of Complex, Roc, domain of DAPkinase FtsK_SpoIIIE PF01580.18 EGC34852.1 - 0.13 11.6 2.1 0.63 9.4 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.6 EGC34852.1 - 0.15 12.2 0.5 4 7.6 0.2 2.7 3 0 0 3 3 2 0 AAA domain AAA_30 PF13604.6 EGC34852.1 - 0.2 11.3 0.1 14 5.4 0.0 2.7 3 0 0 3 3 3 0 AAA domain cobW PF02492.19 EGC34852.1 - 0.25 10.9 1.3 0.33 10.5 0.1 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SH3-WW_linker PF16618.5 EGC34852.1 - 0.53 10.7 5.4 0.91 10.0 5.4 1.3 1 0 0 1 1 1 0 Linker region between SH3 and WW domains on ARHGAP12 AAA_23 PF13476.6 EGC34852.1 - 0.9 10.0 0.0 0.9 10.0 0.0 3.8 4 0 0 4 4 3 0 AAA domain DUF87 PF01935.17 EGC34852.1 - 4.2 7.4 8.6 1.7 8.7 0.1 3.1 3 0 0 3 3 3 0 Helicase HerA, central domain Pex24p PF06398.11 EGC34852.1 - 9.8 5.0 9.6 0.61 9.0 3.1 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin Rad1 PF02144.16 EGC34853.1 - 1.2e-59 201.6 1.4 1.7e-59 201.1 1.4 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 bVLRF1 PF18826.1 EGC34854.1 - 3.1e-50 169.9 0.0 7.6e-50 168.6 0.0 1.7 1 0 0 1 1 1 1 bacteroidetes VLRF1 release factor VATC PF18716.1 EGC34854.1 - 4e-12 45.8 3.2 8.4e-12 44.7 3.2 1.6 1 0 0 1 1 1 1 Vms1-associating treble clef domain Ank_2 PF12796.7 EGC34854.1 - 9.5e-10 38.9 0.0 8.8e-08 32.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC34854.1 - 3.2e-08 33.2 0.1 0.00033 20.9 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.6 EGC34854.1 - 6.7e-07 29.7 0.1 8.2e-06 26.3 0.1 2.4 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC34854.1 - 3.9e-06 27.0 0.0 1.2e-05 25.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC34854.1 - 0.00011 22.5 0.1 0.00059 20.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat DUF2572 PF10833.8 EGC34854.1 - 0.012 15.4 3.7 0.012 15.4 3.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) LSM PF01423.22 EGC34855.1 - 4.4e-09 35.9 0.0 4.6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC34855.1 - 0.00046 20.3 0.0 0.00049 20.2 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain PPTA PF01239.22 EGC34857.1 - 3.5e-38 128.2 26.0 5.5e-10 38.6 1.1 5.8 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat YjbR PF04237.13 EGC34857.1 - 0.096 13.3 0.4 0.58 10.8 0.1 2.3 2 1 0 2 2 2 0 YjbR ATP-synt_E_2 PF08112.11 EGC34857.1 - 1.6 9.0 11.3 1.7 9.0 0.0 3.7 4 0 0 4 4 4 0 ATP synthase epsilon subunit AMP-binding PF00501.28 EGC34859.1 - 2.2e-58 197.8 0.0 2.7e-58 197.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC34859.1 - 4.8e-16 58.4 3.7 4.8e-16 58.4 3.7 2.7 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC34859.1 - 1.4e-11 45.2 0.0 3e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Exo_endo_phos PF03372.23 EGC34860.1 - 3e-10 40.0 0.0 1.3e-09 38.0 0.0 1.9 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family DUF4651 PF15513.6 EGC34861.1 - 0.046 13.5 0.0 0.059 13.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Coiled PF05710.12 EGC34861.1 - 0.19 12.6 0.8 0.23 12.3 0.8 1.1 1 0 0 1 1 1 0 Coiled coil GTP_EFTU PF00009.27 EGC34862.1 - 7.2e-63 211.7 0.0 1.1e-62 211.0 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.18 EGC34862.1 - 8.1e-37 125.7 0.1 2.1e-36 124.4 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.6 EGC34862.1 - 3.7e-33 113.4 0.0 1.2e-32 111.8 0.0 2.0 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.24 EGC34862.1 - 3.7e-26 91.0 0.3 1.5e-25 89.0 0.1 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.25 EGC34862.1 - 8.1e-13 48.6 0.1 2.1e-12 47.3 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RF3_C PF16658.5 EGC34862.1 - 7.9e-07 29.0 0.0 1.9e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Class II release factor RF3, C-terminal domain MMR_HSR1 PF01926.23 EGC34862.1 - 0.00052 20.1 0.0 0.0014 18.7 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase AvrPtoB_bdg PF16847.5 EGC34862.1 - 0.012 16.1 0.8 0.45 11.0 0.0 3.3 4 0 0 4 4 4 0 Avirulence AvrPtoB, BAK1-binding domain FeoB_N PF02421.18 EGC34862.1 - 0.04 13.4 0.2 0.41 10.2 0.0 2.6 2 1 0 2 2 2 0 Ferrous iron transport protein B AIG1 PF04548.16 EGC34862.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 AIG1 family AglB_L1 PF18079.1 EGC34862.1 - 0.18 12.1 0.8 8.6 6.7 0.1 2.6 2 0 0 2 2 2 0 Archaeal glycosylation protein B long peripheral domain Acyltransf_C PF16076.5 EGC34864.1 - 0.025 14.7 1.5 2.3 8.4 0.0 3.5 3 0 0 3 3 3 0 Acyltransferase C-terminus PCuAC PF04314.13 EGC34864.1 - 0.1 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Copper chaperone PCu(A)C SYS1 PF09801.9 EGC34865.1 - 1.9e-45 154.5 7.4 2.3e-45 154.3 7.4 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network TRSP PF12500.8 EGC34865.1 - 0.095 12.6 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 TRSP domain C terminus to PRTase_2 ZIP4_domain PF18292.1 EGC34865.1 - 0.18 11.7 0.1 0.27 11.1 0.1 1.2 1 0 0 1 1 1 0 Zinc transporter ZIP4 domain Ras PF00071.22 EGC34866.1 - 2e-59 199.8 0.1 2.3e-59 199.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34866.1 - 9.9e-33 112.9 0.0 1.4e-32 112.4 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34866.1 - 1.5e-12 47.3 0.0 1.7e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC34866.1 - 9.1e-07 29.0 0.0 1.9e-06 28.0 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC34866.1 - 9.9e-05 22.3 0.3 0.0045 16.9 0.1 2.3 1 1 0 2 2 2 1 RsgA GTPase Gtr1_RagA PF04670.12 EGC34866.1 - 0.00013 21.5 0.0 0.00015 21.2 0.0 1.2 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC34866.1 - 0.00031 20.4 0.0 0.02 14.4 0.0 2.3 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGC34866.1 - 0.0022 17.8 0.1 0.13 12.0 0.1 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.19 EGC34866.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Septin PF00735.18 EGC34866.1 - 0.0049 16.2 0.1 0.024 13.9 0.1 1.9 2 0 0 2 2 2 1 Septin AAA_22 PF13401.6 EGC34866.1 - 0.0053 17.0 0.0 0.013 15.8 0.0 1.6 2 0 0 2 2 2 1 AAA domain ATP_bind_1 PF03029.17 EGC34866.1 - 0.0086 15.9 0.2 0.3 10.8 0.0 2.2 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGC34866.1 - 0.012 15.1 0.1 0.018 14.6 0.1 1.2 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGC34866.1 - 0.014 15.8 0.0 0.021 15.2 0.0 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGC34866.1 - 0.022 14.5 0.0 0.037 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SRPRB PF09439.10 EGC34866.1 - 0.029 13.8 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit TniB PF05621.11 EGC34866.1 - 0.044 13.2 0.0 0.058 12.8 0.0 1.2 1 0 0 1 1 1 0 Bacterial TniB protein AAA_5 PF07728.14 EGC34866.1 - 0.05 13.6 0.0 0.096 12.7 0.0 1.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) G-alpha PF00503.20 EGC34866.1 - 0.053 12.7 0.4 0.25 10.5 0.2 2.0 2 1 0 2 2 2 0 G-protein alpha subunit ATPase_2 PF01637.18 EGC34866.1 - 0.062 13.2 0.1 0.11 12.4 0.1 1.4 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea NACHT PF05729.12 EGC34866.1 - 0.09 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.22 EGC34866.1 - 0.092 11.9 0.1 0.13 11.4 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain NTPase_1 PF03266.15 EGC34866.1 - 0.093 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 NTPase DAP3 PF10236.9 EGC34866.1 - 0.12 11.6 0.2 0.16 11.1 0.2 1.2 1 0 0 1 1 1 0 Mitochondrial ribosomal death-associated protein 3 PHD PF00628.29 EGC34868.1 - 1.9e-12 46.8 9.2 2.3e-12 46.6 9.2 1.1 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.22 EGC34868.1 - 0.75 9.7 8.0 0.17 11.8 2.5 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-NOSIP PF15906.5 EGC34869.1 - 2.1e-10 40.6 0.3 2.1e-10 40.6 0.3 2.5 3 0 0 3 3 3 1 Zinc-finger of nitric oxide synthase-interacting protein zf-RING_UBOX PF13445.6 EGC34869.1 - 1.2e-08 34.8 14.0 6.9e-05 22.8 1.3 3.3 2 1 1 3 3 3 2 RING-type zinc-finger Rtf2 PF04641.12 EGC34869.1 - 2.1e-08 33.9 6.4 2.1e-08 33.9 6.4 3.6 2 2 1 3 3 2 2 Rtf2 RING-finger zf-RING_2 PF13639.6 EGC34869.1 - 4.3e-06 27.0 20.6 0.0015 18.8 10.5 2.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.25 EGC34869.1 - 0.00016 21.4 18.3 0.049 13.5 3.3 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC34869.1 - 0.00016 21.4 3.8 0.00016 21.4 3.8 3.9 2 2 2 4 4 4 2 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC34869.1 - 0.00079 19.3 23.0 0.074 13.0 14.4 3.0 2 1 1 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC34869.1 - 0.0017 18.1 24.4 0.089 12.6 2.9 2.6 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC34869.1 - 0.03 14.5 2.5 0.03 14.5 2.5 3.2 2 1 1 3 3 3 0 zinc finger of C3HC4-type, RING DUF3439 PF11921.8 EGC34869.1 - 0.056 13.4 0.7 0.056 13.4 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) UPF0560 PF10577.9 EGC34869.1 - 0.11 11.0 4.8 0.15 10.6 4.8 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 TEX19 PF15553.6 EGC34869.1 - 0.17 11.9 1.2 0.27 11.2 1.2 1.3 1 0 0 1 1 1 0 Testis-expressed protein 19 Presenilin PF01080.17 EGC34869.1 - 1.8 7.2 8.3 2.2 6.9 8.3 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGC34869.1 - 2.8 6.7 9.2 3.7 6.3 9.2 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF3987 PF13148.6 EGC34869.1 - 3 6.7 4.3 4.2 6.3 4.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) EMC3_TMCO1 PF01956.16 EGC34869.1 - 3.6 7.3 6.6 6 6.6 6.6 1.4 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Membralin PF09746.9 EGC34869.1 - 6.8 5.6 6.1 8.7 5.3 6.1 1.1 1 0 0 1 1 1 0 Tumour-associated protein WH2 PF02205.20 EGC34870.1 - 1.5e-17 62.8 1.0 6.7e-07 28.9 0.2 3.1 3 0 0 3 3 3 3 WH2 motif SET PF00856.28 EGC34871.1 - 2.5e-21 76.8 0.2 1.1e-20 74.7 0.2 1.9 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.16 EGC34871.1 - 1.8e-15 57.5 7.4 1.8e-15 57.5 7.4 2.4 2 1 0 2 2 2 1 Pre-SET motif EF-hand_1 PF00036.32 EGC34872.1 - 2.4e-24 83.0 8.9 5.5e-09 34.9 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGC34872.1 - 1.2e-20 71.6 5.7 4.2e-08 32.5 0.1 5.3 4 2 2 6 6 6 4 EF-hand domain EF-hand_7 PF13499.6 EGC34872.1 - 1.6e-20 73.3 1.9 2.2e-10 40.8 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC34872.1 - 1.3e-11 43.4 7.5 2.5e-07 29.9 0.3 5.0 5 0 0 5 5 5 2 EF hand EF-hand_9 PF14658.6 EGC34872.1 - 1.1e-10 41.7 0.1 2.6e-06 27.7 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.6 EGC34872.1 - 1.4e-10 40.8 8.4 0.014 15.2 0.2 4.3 2 2 2 4 4 4 4 EF-hand domain pair DUF3892 PF13031.6 EGC34872.1 - 0.0078 16.8 0.6 0.18 12.4 0.2 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3892) EF-hand_14 PF17959.1 EGC34872.1 - 0.01 16.2 0.7 0.54 10.6 0.5 2.6 1 1 1 2 2 2 0 EF-hand domain Caleosin PF05042.13 EGC34872.1 - 0.012 15.6 1.0 1.4 8.8 0.0 2.9 1 1 1 3 3 3 0 Caleosin related protein UPF0154 PF03672.13 EGC34872.1 - 0.017 15.1 0.1 1.5 8.9 0.0 2.7 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) DUF2794 PF10984.8 EGC34872.1 - 0.099 12.8 0.0 0.14 12.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2794) EF-hand_4 PF12763.7 EGC34872.1 - 0.11 12.4 1.3 2.3 8.2 0.1 2.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand SH3_16 PF18348.1 EGC34872.1 - 0.13 12.1 0.0 2.3 8.1 0.0 2.3 2 0 0 2 2 2 0 Bacterial dipeptidyl-peptidase Sh3 domain Med7 PF05983.11 EGC34873.1 - 1.9e-54 184.7 17.1 4.7e-54 183.4 17.1 1.7 1 1 0 1 1 1 1 MED7 protein SMN PF06003.12 EGC34873.1 - 0.0081 15.5 2.4 0.0081 15.5 2.4 2.0 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) TMEM174 PF15029.6 EGC34873.1 - 0.65 9.7 5.8 1.1 8.9 5.8 1.4 1 0 0 1 1 1 0 Transmembrane protein 174 FAM60A PF15396.6 EGC34873.1 - 7.7 6.5 10.9 1.9 8.4 3.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A TPR_1 PF00515.28 EGC34875.1 - 4.2e-57 187.8 23.1 5.4e-08 32.3 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGC34875.1 - 2.9e-49 161.2 20.7 1.4e-05 24.9 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.6 EGC34875.1 - 1.2e-38 128.0 16.7 0.00013 21.9 1.0 10.8 10 1 0 10 10 10 7 Tetratricopeptide repeat TPR_17 PF13431.6 EGC34875.1 - 3.7e-38 127.2 15.7 0.00028 21.0 0.1 11.2 11 0 0 11 11 11 8 Tetratricopeptide repeat TPR_16 PF13432.6 EGC34875.1 - 1.1e-30 106.0 0.3 5.1e-08 33.4 0.0 6.4 5 1 1 6 6 6 5 Tetratricopeptide repeat TPR_12 PF13424.6 EGC34875.1 - 8.4e-28 96.5 19.6 1.9e-05 24.8 1.9 7.1 5 1 0 6 6 6 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGC34875.1 - 8.4e-26 88.5 2.4 0.0019 18.9 0.0 9.1 5 2 4 9 9 9 6 Tetratricopeptide repeat TPR_7 PF13176.6 EGC34875.1 - 9e-23 78.6 9.4 0.033 14.2 0.1 10.1 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_6 PF13174.6 EGC34875.1 - 9.6e-21 73.0 21.5 0.041 14.5 0.0 9.6 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGC34875.1 - 2e-18 65.8 29.3 2.3e-05 24.0 0.5 10.1 3 3 6 9 9 9 5 TPR repeat TPR_19 PF14559.6 EGC34875.1 - 3.4e-16 59.5 27.3 0.00011 22.7 0.0 7.5 5 1 3 8 8 7 6 Tetratricopeptide repeat TPR_9 PF13371.6 EGC34875.1 - 7.5e-13 48.4 7.2 0.0049 17.0 0.1 6.5 3 2 3 7 7 7 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC34875.1 - 6e-12 45.6 12.6 1e-07 32.0 0.5 4.0 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGC34875.1 - 4.6e-09 35.9 24.2 1.8e-06 27.4 2.4 4.1 1 1 2 3 3 3 2 Tetratricopeptide repeat ChAPs PF09295.10 EGC34875.1 - 5.4e-05 22.4 1.3 0.022 13.8 0.0 3.3 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_20 PF14561.6 EGC34875.1 - 0.002 18.5 19.4 0.47 10.8 0.0 6.9 4 2 4 8 8 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC34875.1 - 0.05 13.5 12.7 2.1 8.3 0.0 6.2 7 0 0 7 7 6 0 Tetratricopeptide repeat MIT PF04212.18 EGC34875.1 - 1.4 9.1 19.9 27 4.9 2.3 6.7 6 1 1 7 7 7 0 MIT (microtubule interacting and transport) domain BTAD PF03704.17 EGC34875.1 - 7.4 7.0 14.2 8.7 6.8 0.0 4.2 3 1 0 3 3 3 0 Bacterial transcriptional activator domain TFIIA PF03153.13 EGC34875.1 - 7.6 6.4 62.0 0.17 11.9 27.9 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 EGC34876.1 - 5.1e-10 39.1 0.1 8.2e-10 38.4 0.1 1.3 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGC34876.1 - 1.1e-05 25.2 5.2 3.1e-05 23.8 0.8 2.8 2 1 1 3 3 3 2 Homeobox KN domain DUF4291 PF14124.6 EGC34877.1 - 2.3e-66 223.1 4.5 2.7e-66 222.9 4.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) FPN1 PF06963.12 EGC34878.1 - 1.3e-80 271.1 6.9 1.5e-80 270.9 6.9 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.16 EGC34878.1 - 7.6e-10 38.2 15.1 2.2e-09 36.7 9.4 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily FUN14 PF04930.15 EGC34879.1 - 2.6 8.5 6.6 2.3 8.7 1.6 2.8 2 1 0 2 2 2 0 FUN14 family LIM PF00412.22 EGC34880.1 - 2.1e-11 43.9 1.9 4.3e-11 42.9 1.9 1.5 1 0 0 1 1 1 1 LIM domain AIF_C PF14721.6 EGC34880.1 - 0.27 11.6 4.4 0.37 11.1 3.9 1.4 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Trypan_PARP PF05887.11 EGC34880.1 - 1.3 9.0 4.5 2.5 8.1 4.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4298 PF14131.6 EGC34881.1 - 0.0029 17.5 0.8 0.0029 17.5 0.8 4.0 4 0 0 4 4 4 2 Domain of unknown function (DUF4298) Metallophos PF00149.28 EGC34882.1 - 3.2e-07 31.1 3.4 6.1e-07 30.1 3.4 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGC34882.1 - 0.006 17.1 0.0 0.016 15.7 0.0 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain TMEMspv1-c74-12 PF11044.8 EGC34882.1 - 0.19 11.7 1.5 0.48 10.4 1.5 1.7 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein EMC3_TMCO1 PF01956.16 EGC34883.1 - 2.1e-36 125.2 1.2 2.6e-36 124.9 1.2 1.0 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like DivIC PF04977.15 EGC34883.1 - 0.015 15.1 0.8 0.027 14.2 0.8 1.4 1 0 0 1 1 1 0 Septum formation initiator CHD5 PF04420.14 EGC34883.1 - 0.017 15.0 1.8 0.049 13.5 1.8 1.7 1 1 0 1 1 1 0 CHD5-like protein DUF3964 PF13107.6 EGC34883.1 - 0.052 13.9 0.0 0.072 13.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3964) Wbp11 PF09429.10 EGC34883.1 - 0.086 13.2 6.9 0.12 12.8 6.9 1.2 1 0 0 1 1 1 0 WW domain binding protein 11 DUF4407 PF14362.6 EGC34883.1 - 0.55 9.5 3.1 0.86 8.9 3.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) HTH_38 PF13936.6 EGC34884.1 - 5.1e-08 32.5 1.6 6e-08 32.3 0.1 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.6 EGC34884.1 - 2.1e-06 27.4 0.0 4.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Homeodomain-like domain HTH_32 PF13565.6 EGC34884.1 - 5.5e-06 26.9 0.0 1.8e-05 25.3 0.0 1.7 1 1 1 2 2 2 1 Homeodomain-like domain HTH_29 PF13551.6 EGC34884.1 - 1e-05 25.4 0.0 1.5e-05 24.9 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_7 PF02796.15 EGC34884.1 - 0.00032 20.7 0.3 0.008 16.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.12 EGC34884.1 - 0.00061 19.4 0.0 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.13 EGC34884.1 - 0.012 15.2 0.6 0.026 14.1 0.3 1.6 2 0 0 2 2 2 0 CENP-B N-terminal DNA-binding domain Type2_restr_D3 PF16902.5 EGC34884.1 - 0.023 14.6 0.7 0.27 11.2 0.1 2.3 2 1 0 2 2 2 0 Type-2 restriction enzyme D3 domain Sigma70_r4 PF04545.16 EGC34884.1 - 0.07 12.7 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_40 PF14493.6 EGC34884.1 - 0.091 13.2 0.2 0.12 12.8 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4214 PF13946.6 EGC34885.1 - 0.035 14.2 0.0 0.047 13.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) Ank_3 PF13606.6 EGC34886.1 - 6.5e-07 29.2 0.0 0.15 12.7 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.6 EGC34886.1 - 3.5e-05 24.3 0.0 0.058 14.0 0.0 2.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC34886.1 - 0.00013 22.5 0.0 0.00038 21.0 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC34886.1 - 0.18 12.2 0.0 51 4.4 0.0 3.0 2 1 1 3 3 3 0 Ankyrin repeats (many copies) Aconitase PF00330.20 EGC34887.1 - 2e-154 515.0 0.0 2.5e-154 514.7 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGC34887.1 - 4.9e-45 153.1 0.0 1.1e-44 151.9 0.0 1.6 1 0 0 1 1 1 1 Aconitase C-terminal domain DUF521 PF04412.13 EGC34887.1 - 0.085 11.5 0.0 0.15 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF521) Adaptin_N PF01602.20 EGC34888.1 - 5.6e-152 507.0 18.0 8.4e-152 506.4 18.0 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGC34888.1 - 2.4e-66 222.7 8.1 9.7e-64 214.3 1.2 2.8 2 0 0 2 2 2 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGC34888.1 - 3e-24 85.2 0.0 7.8e-24 83.9 0.0 1.7 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.6 EGC34888.1 - 1.4e-20 73.4 4.3 1.8e-06 28.2 0.0 5.5 3 1 2 5 5 5 5 HEAT repeats HEAT PF02985.22 EGC34888.1 - 4.9e-11 41.9 3.7 0.043 14.1 0.0 6.2 5 0 0 5 5 5 3 HEAT repeat RTP1_C1 PF10363.9 EGC34888.1 - 8.7e-07 29.1 6.1 0.25 11.5 0.0 5.3 2 2 2 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 Cnd3 PF12719.7 EGC34888.1 - 1.1e-05 24.8 5.1 0.00014 21.2 0.1 3.5 3 2 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain CLASP_N PF12348.8 EGC34888.1 - 2.2e-05 24.2 2.6 0.075 12.6 0.2 3.7 2 2 0 2 2 2 2 CLASP N terminal Alpha_adaptinC2 PF02883.20 EGC34888.1 - 0.00013 22.2 0.1 0.00048 20.4 0.1 2.0 1 0 0 1 1 1 1 Adaptin C-terminal domain Arm PF00514.23 EGC34888.1 - 0.016 15.2 5.4 9.5 6.4 0.0 5.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat TPR_19 PF14559.6 EGC34888.1 - 0.059 13.9 0.1 0.27 11.8 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat FNIP PF05725.12 EGC34889.1 - 8e-08 32.3 22.6 0.033 14.3 1.2 5.3 3 2 3 6 6 6 5 FNIP Repeat LRR_5 PF13306.6 EGC34889.1 - 0.0067 16.4 5.0 0.023 14.7 1.2 2.4 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Lung_7-TM_R PF06814.13 EGC34891.1 - 5.4e-09 35.7 37.1 9.6e-09 34.9 37.1 1.5 1 1 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.9 EGC34891.1 - 8.3e-07 28.7 23.2 8.3e-07 28.7 23.2 2.6 2 1 1 3 3 3 1 Rhodopsin-like GPCR transmembrane domain PH_4 PF15404.6 EGC34891.1 - 1.1 9.0 6.2 10 5.9 2.4 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain Secretin_N_2 PF07655.13 EGC34891.1 - 5.2 7.7 23.2 0.074 13.6 13.1 2.7 3 0 0 3 3 3 0 Secretin N-terminal domain Macro PF01661.21 EGC34892.1 - 1.2e-33 115.7 0.1 2.5e-33 114.6 0.1 1.6 1 0 0 1 1 1 1 Macro domain WWE PF02825.20 EGC34892.1 - 2.7e-21 75.9 30.7 5.3e-09 36.6 1.1 4.1 4 0 0 4 4 4 3 WWE domain bZIP_2 PF07716.15 EGC34893.1 - 2.2e-06 27.7 10.6 2.2e-06 27.7 10.6 2.8 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_1 PF00170.21 EGC34893.1 - 5.4e-05 23.2 8.3 5.4e-05 23.2 8.3 3.0 3 0 0 3 3 3 1 bZIP transcription factor DUF2674 PF10879.8 EGC34893.1 - 0.00071 19.1 0.0 0.0022 17.5 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2674) PikAIV_N PF18605.1 EGC34893.1 - 0.095 12.3 2.2 0.24 11.0 2.2 1.7 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain L27 PF02828.16 EGC34893.1 - 0.38 10.6 2.8 0.92 9.3 0.0 3.1 3 0 0 3 3 3 0 L27 domain zf-rbx1 PF12678.7 EGC34894.1 - 1.2e-06 28.7 3.3 2e-06 28.0 0.9 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC34894.1 - 2.9e-06 27.5 2.2 2.9e-06 27.5 2.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGC34894.1 - 3.5e-05 23.6 3.6 9.3e-05 22.2 0.9 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC34894.1 - 0.00014 21.6 5.3 0.00029 20.6 2.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC34894.1 - 0.00069 19.5 2.4 0.0014 18.5 0.6 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC34894.1 - 0.00069 19.3 2.4 0.012 15.4 0.4 2.5 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGC34894.1 - 0.00088 19.1 1.0 0.00088 19.1 1.0 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_3 PF13920.6 EGC34894.1 - 0.0013 18.6 2.5 0.0065 16.3 0.5 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGC34894.1 - 0.008 16.2 1.4 0.008 16.2 1.4 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC34894.1 - 0.022 14.9 0.7 0.022 14.9 0.7 1.8 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGC34894.1 - 0.035 14.1 2.2 0.035 14.1 2.2 2.2 2 1 1 3 3 3 0 RING-type zinc-finger Duffy_binding PF05424.11 EGC34894.1 - 0.045 13.8 1.7 0.069 13.2 1.7 1.2 1 0 0 1 1 1 0 Duffy binding domain DZR PF12773.7 EGC34894.1 - 0.056 13.5 0.4 0.19 11.8 0.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EGC34894.1 - 0.2 11.3 6.8 0.12 12.1 3.3 2.0 2 0 0 2 2 2 0 Zinc-ribbon, C4HC2 type FANCL_C PF11793.8 EGC34894.1 - 2.5 8.3 9.3 1.7 8.9 4.5 2.5 2 1 0 2 2 1 0 FANCL C-terminal domain IBR PF01485.21 EGC34895.1 - 6.6e-22 77.5 31.6 1.7e-14 53.8 6.6 3.9 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain UBA PF00627.31 EGC34895.1 - 0.0015 18.4 0.0 0.0039 17.0 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_5 PF14634.6 EGC34895.1 - 0.0048 16.8 6.5 0.0048 16.8 6.5 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC34895.1 - 0.0064 16.3 5.3 0.0064 16.3 5.3 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC34895.1 - 0.68 10.3 42.0 0.044 14.1 6.9 4.1 2 1 1 3 3 3 0 Ring finger domain Cas_Cas6 PF01881.16 EGC34895.1 - 2.6 8.6 8.8 8.8 6.9 3.7 2.6 2 0 0 2 2 2 0 CRISPR associated protein Cas6 Gpi1 PF05024.15 EGC34896.1 - 3.8e-59 199.9 17.0 1e-58 198.5 17.0 1.8 1 0 0 1 1 1 1 N-acetylglucosaminyl transferase component (Gpi1) TFIIA PF03153.13 EGC34896.1 - 0.025 14.6 20.6 0.011 15.7 8.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGC34896.1 - 1.9 7.1 17.7 6.6 5.4 0.0 2.7 2 1 0 2 2 2 0 Presenilin Peroxin-13_N PF04088.13 EGC34896.1 - 9.6 6.5 12.4 3.9e+02 1.2 0.0 3.5 2 1 0 2 2 2 0 Peroxin 13, N-terminal region Ribosomal_L22 PF00237.19 EGC34897.1 - 3.4e-20 72.2 0.6 6.1e-20 71.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF3568 PF12092.8 EGC34897.1 - 0.45 10.6 4.5 0.85 9.7 4.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Peptidase_C48 PF02902.19 EGC34898.1 - 2.9e-43 148.2 1.6 3.8e-43 147.9 1.6 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain 3Beta_HSD PF01073.19 EGC34899.1 - 5.5e-71 238.8 0.0 7.1e-71 238.5 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC34899.1 - 1.7e-35 122.6 0.0 2.3e-35 122.2 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC34899.1 - 3.1e-19 69.5 0.0 6.3e-17 62.0 0.0 2.4 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC34899.1 - 6.5e-15 55.5 0.0 8.8e-15 55.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC34899.1 - 1.1e-14 54.3 0.0 1.4e-10 40.8 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein Polysacc_synt_2 PF02719.15 EGC34899.1 - 2.3e-09 36.8 0.1 6.3e-09 35.4 0.1 1.7 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGC34899.1 - 2.7e-08 33.3 0.0 3.9e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.13 EGC34899.1 - 4.7e-06 26.3 0.0 7.3e-06 25.7 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EGC34899.1 - 0.0017 18.3 0.3 0.036 14.0 0.3 2.4 1 1 0 1 1 1 1 KR domain Sacchrp_dh_NADP PF03435.18 EGC34899.1 - 0.0047 17.2 0.1 0.02 15.2 0.1 2.0 1 1 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain PAXNEB PF05625.11 EGC34901.1 - 8e-95 318.1 0.2 8e-95 318.1 0.2 2.4 2 0 0 2 2 2 1 PAXNEB protein DEAD PF00270.29 EGC34901.1 - 1.9e-14 53.8 0.0 4.3e-14 52.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGC34901.1 - 2.6e-13 50.3 0.0 2.6e-13 50.3 0.0 4.2 4 2 0 4 4 4 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGC34901.1 - 2.1e-06 28.1 3.8 1.2e-05 25.6 0.0 3.9 2 1 1 3 3 3 1 Helicase conserved C-terminal domain ATPase PF06745.13 EGC34901.1 - 0.03 13.7 1.4 0.86 8.9 0.2 3.3 4 0 0 4 4 4 0 KaiC VPS9 PF02204.18 EGC34901.1 - 0.062 13.5 0.2 0.27 11.5 0.2 2.1 1 0 0 1 1 1 0 Vacuolar sorting protein 9 (VPS9) domain RIH_assoc PF08454.11 EGC34901.1 - 2 8.3 11.6 0.32 10.9 0.4 4.2 3 0 0 3 3 3 0 RyR and IP3R Homology associated Biopterin_H PF00351.21 EGC34902.1 - 8.4e-169 560.8 0.0 1e-168 560.5 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.25 EGC34902.1 - 0.0013 18.5 0.0 0.0027 17.4 0.0 1.6 1 0 0 1 1 1 1 ACT domain Cellulase PF00150.18 EGC34902.1 - 0.16 11.3 0.0 0.25 10.7 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MTHFR PF02219.17 EGC34903.1 - 2.2e-119 398.0 0.0 3.4e-119 397.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase LPMO_10 PF03067.15 EGC34904.1 - 4.3e-22 79.7 0.3 5.6e-22 79.4 0.3 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading LPMO_10 PF03067.15 EGC34905.1 - 1.2e-29 104.4 0.8 1.5e-29 104.1 0.8 1.1 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading DUF3986 PF13143.6 EGC34905.1 - 0.11 13.5 1.7 0.11 13.5 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3986) CLZ PF16526.5 EGC34906.1 - 0.0064 16.8 10.6 0.0064 16.8 10.6 5.4 3 3 3 6 6 6 1 C-terminal leucine zipper domain of cyclic nucleotide-gated channels CEP63 PF17045.5 EGC34906.1 - 0.17 11.8 65.4 0.24 11.3 6.5 3.9 1 1 3 4 4 4 0 Centrosomal protein of 63 kDa DUF2576 PF10845.8 EGC34906.1 - 0.19 11.3 0.1 0.19 11.3 0.1 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF2576) TPR_MLP1_2 PF07926.12 EGC34906.1 - 3.8 7.6 75.1 1.8 8.6 21.1 3.8 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein PMSR PF01625.21 EGC34907.1 - 6e-66 221.3 1.2 7.1e-66 221.1 1.2 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase CAF1 PF04857.20 EGC34907.1 - 0.05 12.8 0.1 0.065 12.4 0.1 1.2 1 0 0 1 1 1 0 CAF1 family ribonuclease Patched PF02460.18 EGC34908.1 - 3.3e-100 336.4 19.5 1.2e-99 334.6 12.2 2.7 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.8 EGC34908.1 - 1.5e-50 171.0 8.2 1.5e-50 171.0 8.2 2.9 2 0 0 2 2 2 1 Sterol-sensing domain of SREBP cleavage-activation NPC1_N PF16414.5 EGC34908.1 - 6.5e-23 81.5 15.0 1.8e-22 80.1 15.0 1.7 1 1 0 1 1 1 1 Niemann-Pick C1 N terminus ACR_tran PF00873.19 EGC34908.1 - 6.7e-05 20.8 17.4 0.00012 19.9 17.4 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.15 EGC34908.1 - 0.00059 18.9 1.8 0.00059 18.9 1.8 2.6 2 0 0 2 2 2 1 MMPL family Chordopox_A30L PF06015.12 EGC34908.1 - 0.1 12.4 0.1 0.3 10.9 0.1 1.8 1 0 0 1 1 1 0 Chordopoxvirus A30L protein BAR_3_WASP_bdg PF10456.9 EGC34909.1 - 0.061 12.8 0.0 0.079 12.4 0.0 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein GpcrRhopsn4 PF10192.9 EGC34910.1 - 2.5e-70 236.8 17.8 2.5e-70 236.8 17.8 1.7 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.13 EGC34910.1 - 0.00089 18.6 18.8 0.0038 16.5 18.8 2.0 1 1 0 1 1 1 1 Lung seven transmembrane receptor DUF2569 PF10754.9 EGC34910.1 - 0.02 15.4 0.7 0.02 15.4 0.7 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2569) Fungus-induced PF10917.8 EGC34910.1 - 1.7 9.1 4.8 0.89 9.9 0.3 2.9 2 0 0 2 2 2 0 Fungus-induced protein DUF1132 PF06575.12 EGC34911.1 - 0.062 13.7 0.4 0.21 12.0 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) Pentapeptide PF00805.22 EGC34912.1 - 2.2e-43 145.4 39.3 5.2e-14 51.6 5.8 4.5 2 2 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGC34912.1 - 1.2e-26 92.7 7.9 3.2e-14 52.8 1.9 2.9 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGC34912.1 - 1.5e-22 79.4 6.2 1.3e-08 34.8 4.6 4.9 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 EGC34912.1 - 5.9e-18 65.0 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain KHA PF11834.8 EGC34912.1 - 1.3e-14 54.0 0.0 2.4e-14 53.2 0.0 1.4 1 0 0 1 1 1 1 KHA, dimerisation domain of potassium ion channel BTB PF00651.31 EGC34912.1 - 3.8e-05 23.9 0.0 7.1e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EGC34912.1 - 0.00046 20.2 0.0 0.001 19.1 0.0 1.6 1 0 0 1 1 1 1 BTB/POZ domain NAD_binding_8 PF13450.6 EGC34912.1 - 0.17 12.1 0.0 0.9 9.8 0.0 2.2 2 0 0 2 2 2 0 NAD(P)-binding Rossmann-like domain COesterase PF00135.28 EGC34913.1 - 2.5e-124 416.0 0.7 5.6e-124 414.8 0.7 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC34913.1 - 5.1e-07 29.8 0.0 1.3e-06 28.5 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC34913.1 - 0.00026 20.6 0.0 0.00047 19.7 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Thg1 PF04446.12 EGC34914.1 - 7.6e-52 174.6 0.4 1.4e-51 173.7 0.4 1.4 1 0 0 1 1 1 1 tRNAHis guanylyltransferase Thg1C PF14413.6 EGC34914.1 - 2.3e-42 144.0 4.1 9.6e-42 142.0 4.1 1.8 1 1 0 1 1 1 1 Thg1 C terminal domain Cystatin PF00031.21 EGC34915.1 - 0.0033 17.6 0.6 0.0072 16.6 0.6 1.6 1 1 0 1 1 1 1 Cystatin domain Pro-kuma_activ PF09286.11 EGC34916.1 - 2.5e-29 102.4 0.0 2.8e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HSP90 PF00183.18 EGC34917.1 - 8.7e-176 585.8 21.1 1.2e-175 585.3 21.1 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c PF02518.26 EGC34917.1 - 5.5e-13 49.4 0.9 3.6e-12 46.8 0.4 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGC34917.1 - 1.3e-10 41.3 0.2 3.3e-10 39.9 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase ComA PF02679.15 EGC34917.1 - 0.035 13.6 0.2 0.14 11.6 0.2 2.0 1 0 0 1 1 1 0 (2R)-phospho-3-sulfolactate synthase (ComA) Ribosomal_L24e PF01246.20 EGC34918.1 - 8.3e-26 90.0 0.9 8.3e-26 90.0 0.9 2.1 2 1 1 3 3 3 1 Ribosomal protein L24e DUF775 PF05603.12 EGC34918.1 - 0.012 15.2 1.2 0.013 15.0 1.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF775) IBN_N PF03810.19 EGC34918.1 - 0.02 14.8 0.3 0.028 14.3 0.3 1.3 1 0 0 1 1 1 0 Importin-beta N-terminal domain RNase_J_C PF17770.1 EGC34918.1 - 3.1 8.9 6.3 6.4 7.9 0.1 2.3 1 1 1 2 2 2 0 Ribonuclease J C-terminal domain Mucin PF01456.17 EGC34919.1 - 0.0061 16.6 12.3 0.012 15.7 12.3 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.11 EGC34919.1 - 0.022 13.0 9.5 0.03 12.6 9.5 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.22 EGC34920.1 - 1.3e-29 102.9 0.3 1.5e-29 102.7 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34920.1 - 1.2e-09 38.4 0.0 1.7e-09 37.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34920.1 - 0.0012 18.3 0.0 0.0015 18.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family DAPDH_C PF16654.5 EGC34920.1 - 0.0019 18.1 0.0 0.0027 17.6 0.0 1.2 1 0 0 1 1 1 1 Diaminopimelic acid dehydrogenase C-terminal domain LZ3wCH PF18517.1 EGC34920.1 - 0.028 14.5 0.0 0.074 13.2 0.0 1.7 2 0 0 2 2 2 0 Leucine zipper with capping helix domain zf-C2H2 PF00096.26 EGC34921.1 - 2.8e-18 65.3 30.6 3.3e-05 24.1 1.2 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-H2C2_2 PF13465.6 EGC34921.1 - 1.6e-16 59.9 33.8 1.7e-06 28.2 1.1 5.9 5 0 0 5 5 5 3 Zinc-finger double domain zf-met PF12874.7 EGC34921.1 - 6.1e-05 23.3 7.7 0.9 10.0 0.6 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_4 PF13894.6 EGC34921.1 - 8.7e-05 23.0 23.3 0.013 16.3 1.1 5.9 7 0 0 7 7 7 4 C2H2-type zinc finger zf-C2H2_jaz PF12171.8 EGC34921.1 - 0.00057 20.1 17.0 0.089 13.1 2.0 5.0 4 0 0 4 4 4 2 Zinc-finger double-stranded RNA-binding zf-C2H2_aberr PF17017.5 EGC34921.1 - 0.0011 19.2 10.6 0.0088 16.2 0.1 4.2 1 1 3 4 4 4 1 Aberrant zinc-finger zf-C2H2_8 PF15909.5 EGC34921.1 - 0.019 15.2 12.5 0.057 13.7 5.9 2.6 1 1 2 3 3 3 0 C2H2-type zinc ribbon zf-C2H2_6 PF13912.6 EGC34921.1 - 0.066 13.2 0.7 0.066 13.2 0.7 4.6 4 1 0 4 4 4 0 C2H2-type zinc finger zf-DNA_Pol PF08996.10 EGC34921.1 - 1.6 8.4 6.4 1.3 8.8 0.4 2.2 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger DUF1065 PF06358.11 EGC34923.1 - 0.13 12.2 0.6 0.17 11.9 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1065) PGP_phosphatase PF09419.10 EGC34924.1 - 3.4e-50 169.9 0.0 4.3e-50 169.6 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.6 EGC34924.1 - 1e-06 28.7 0.0 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like HAD_2 PF13419.6 EGC34924.1 - 0.00027 21.1 0.2 0.0053 16.9 0.0 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGC34924.1 - 0.00038 20.8 0.1 0.34 11.2 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.21 EGC34925.1 - 5.5e-20 71.4 0.0 1e-19 70.5 0.0 1.5 1 0 0 1 1 1 1 Acyltransferase DUF898 PF05987.13 EGC34925.1 - 0.054 12.5 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) OTU PF02338.19 EGC34926.1 - 8e-12 45.8 0.2 2.2e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease TIG PF01833.24 EGC34927.1 - 1.9e-13 50.3 50.7 0.0016 18.5 4.1 7.7 5 2 2 7 7 7 7 IPT/TIG domain EGF_2 PF07974.13 EGC34927.1 - 1.4 9.3 10.3 3.9 7.9 10.3 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.24 EGC34928.1 - 6.8e-13 48.5 50.0 0.0066 16.5 3.0 7.9 5 2 2 7 7 7 7 IPT/TIG domain EGF_2 PF07974.13 EGC34928.1 - 1.4 9.3 10.3 3.9 7.9 10.3 1.8 1 0 0 1 1 1 0 EGF-like domain FIVAR PF07554.13 EGC34929.1 - 0.91 10.3 12.0 0.64 10.8 8.7 2.2 2 0 0 2 2 2 0 FIVAR domain WD40 PF00400.32 EGC34930.1 - 2.4e-26 91.4 15.8 0.00011 22.9 0.8 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34930.1 - 9.1e-09 35.5 0.1 0.013 15.8 0.0 4.7 4 1 0 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGC34930.1 - 0.0014 17.3 0.0 0.095 11.2 0.0 2.7 3 0 0 3 3 3 1 Cytochrome D1 heme domain PQQ PF01011.21 EGC34930.1 - 0.047 13.6 0.1 0.22 11.5 0.1 2.2 1 0 0 1 1 1 0 PQQ enzyme repeat YL1_C PF08265.11 EGC34930.1 - 0.2 11.4 0.7 0.66 9.8 0.7 1.9 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain Caldesmon PF02029.15 EGC34930.1 - 0.29 9.8 23.2 0.4 9.4 23.2 1.1 1 0 0 1 1 1 0 Caldesmon Spec3 PF15795.5 EGC34932.1 - 6.7e-09 36.2 17.7 0.00035 21.1 1.0 2.0 1 1 1 2 2 2 2 Ectodermal ciliogenesis protein Cpn60_TCP1 PF00118.24 EGC34933.1 - 8e-38 130.3 6.7 1.3e-37 129.6 6.7 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF2850 PF11012.8 EGC34933.1 - 0.31 11.4 1.9 9.8 6.6 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2850) Transferase PF02458.15 EGC34934.1 - 8.3e-16 57.7 0.0 1.1e-15 57.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 EGC34934.1 - 0.013 14.2 0.0 0.018 13.8 0.0 1.1 1 0 0 1 1 1 0 Condensation domain Glyco_trans_1_4 PF13692.6 EGC34935.1 - 0.13 12.6 0.0 0.15 12.5 0.0 1.1 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF2660 PF10859.8 EGC34936.1 - 0.016 15.7 2.0 0.41 11.1 0.0 3.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) SWC7 PF17330.2 EGC34936.1 - 0.35 10.9 4.8 0.23 11.5 0.6 2.8 2 0 0 2 2 2 0 SWR1 chromatin-remodelling complex, sub-unit Swc7 LUD_dom PF02589.15 EGC34937.1 - 1.4e-25 90.1 0.1 1.7e-25 89.9 0.1 1.1 1 0 0 1 1 1 1 LUD domain NHL PF01436.21 EGC34937.1 - 0.036 14.1 0.4 0.24 11.5 0.0 2.3 2 0 0 2 2 2 0 NHL repeat SRP_SPB PF02978.19 EGC34938.1 - 9.2e-08 32.6 0.3 9.2e-08 32.6 0.3 2.2 2 1 1 3 3 3 1 Signal peptide binding domain UPF0242 PF06785.11 EGC34938.1 - 0.28 11.3 7.9 0.48 10.5 7.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus FtsJ PF01728.19 EGC34939.1 - 6.5e-51 172.9 0.0 7.3e-51 172.8 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.6 EGC34939.1 - 1.5e-05 24.9 0.0 0.00025 20.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC34939.1 - 0.002 17.5 0.0 0.01 15.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.19 EGC34939.1 - 0.0047 16.7 0.0 0.036 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.6 EGC34939.1 - 0.013 16.2 0.0 0.059 14.1 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGC34939.1 - 0.022 14.6 0.0 0.06 13.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGC34939.1 - 0.04 14.6 0.0 0.095 13.4 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltr_RsmB-F PF01189.17 EGC34939.1 - 0.055 13.1 0.0 3.1 7.4 0.0 2.2 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F FNIP PF05725.12 EGC34941.1 - 5.3e-37 125.7 0.0 3.8e-11 43.0 0.0 5.1 3 1 2 5 5 5 5 FNIP Repeat LRR_5 PF13306.6 EGC34941.1 - 0.003 17.5 0.2 0.024 14.6 0.1 2.1 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) Ldr_toxin PF13940.6 EGC34941.1 - 0.21 11.7 0.0 0.46 10.6 0.0 1.5 1 0 0 1 1 1 0 Toxin Ldr, type I toxin-antitoxin system EGF_2 PF07974.13 EGC34942.1 - 2.6e-18 66.1 113.8 4.9e-05 23.6 13.3 6.8 6 0 0 6 6 6 5 EGF-like domain Laminin_EGF PF00053.24 EGC34942.1 - 1.8e-05 24.8 89.6 0.11 12.6 8.6 6.7 5 1 1 6 6 6 5 Laminin EGF domain TIG PF01833.24 EGC34942.1 - 0.00018 21.5 0.6 0.00018 21.5 0.6 3.7 3 0 0 3 3 3 1 IPT/TIG domain EGF_Tenascin PF18720.1 EGC34942.1 - 0.041 13.9 83.0 0.029 14.4 8.7 6.2 6 0 0 6 6 6 0 Tenascin EGF domain DUF3642 PF12182.8 EGC34942.1 - 0.17 12.2 0.0 0.17 12.2 0.0 3.4 4 0 0 4 4 4 0 Bacterial lipoprotein EGF_2 PF07974.13 EGC34943.1 - 4.8e-19 68.4 123.6 0.0001 22.6 13.0 7.3 7 0 0 7 7 7 6 EGF-like domain Laminin_EGF PF00053.24 EGC34943.1 - 5.7e-06 26.4 102.1 0.06 13.5 7.5 6.9 6 1 1 7 7 7 6 Laminin EGF domain EGF_Tenascin PF18720.1 EGC34943.1 - 0.0044 17.0 7.1 0.0044 17.0 7.1 6.8 6 0 0 6 6 6 4 Tenascin EGF domain DUF3642 PF12182.8 EGC34943.1 - 0.2 11.9 0.0 0.2 11.9 0.0 3.8 4 0 0 4 4 4 0 Bacterial lipoprotein LRR_8 PF13855.6 EGC34943.1 - 0.33 10.7 9.7 1.7 8.4 0.1 4.4 5 0 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EGC34943.1 - 0.9 10.3 4.5 1.6e+02 3.5 0.1 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_4 PF12799.7 EGC34943.1 - 3 8.4 16.1 5.3 7.6 0.0 6.3 6 0 0 6 6 6 0 Leucine Rich repeats (2 copies) EF-hand_7 PF13499.6 EGC34945.1 - 7.9e-19 67.9 18.5 4.8e-08 33.4 1.1 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC34945.1 - 3.8e-17 60.7 6.9 0.00023 20.9 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC34945.1 - 1.3e-16 58.8 8.0 0.0013 18.1 0.3 4.4 4 0 0 4 4 4 4 EF hand EF-hand_5 PF13202.6 EGC34945.1 - 4.8e-08 32.1 2.4 0.27 10.8 0.0 4.5 4 0 0 4 4 4 4 EF hand DUF4777 PF16007.5 EGC34945.1 - 6.9e-06 26.2 1.4 0.0052 17.0 0.1 3.9 1 1 3 4 4 4 1 Domain of unknown function (DUF4777) SPARC_Ca_bdg PF10591.9 EGC34945.1 - 7.3e-06 26.3 3.8 0.15 12.4 0.1 2.9 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.6 EGC34945.1 - 0.00095 19.0 6.2 0.076 12.9 0.5 3.3 3 0 0 3 3 3 1 EF-hand domain pair Caleosin PF05042.13 EGC34945.1 - 0.006 16.5 2.7 0.19 11.6 0.1 2.9 1 1 2 3 3 3 1 Caleosin related protein DUF2624 PF11116.8 EGC34945.1 - 0.029 15.2 1.4 0.029 15.2 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Phage_int_SAM_4 PF13495.6 EGC34945.1 - 0.079 13.4 0.8 7.2 7.2 0.0 3.2 3 1 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain pP_pnuc_1 PF18165.1 EGC34945.1 - 0.1 12.5 2.9 0.12 12.3 1.3 1.9 1 1 1 2 2 2 0 Predicted pPIWI-associating nuclease Fe_hyd_lg_C PF02906.14 EGC34945.1 - 0.44 10.2 6.1 3.2 7.3 0.7 2.8 1 1 2 3 3 3 0 Iron only hydrogenase large subunit, C-terminal domain RNase_J_C PF17770.1 EGC34945.1 - 0.53 11.4 4.4 13 6.9 0.3 2.7 3 0 0 3 3 3 0 Ribonuclease J C-terminal domain PCO_ADO PF07847.12 EGC34946.1 - 3.3e-37 127.9 0.1 4e-37 127.6 0.1 1.1 1 0 0 1 1 1 1 PCO_ADO CDO_I PF05995.12 EGC34946.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Cysteine dioxygenase type I EF-hand_1 PF00036.32 EGC34947.1 - 1.7e-15 55.3 8.3 5.8e-05 22.4 0.1 5.8 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.6 EGC34947.1 - 2.2e-14 53.6 8.2 8e-07 29.4 0.3 4.1 3 2 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC34947.1 - 2.2e-13 49.0 6.4 5.6e-06 25.6 0.2 5.6 5 0 0 5 5 5 2 EF hand EF-hand_6 PF13405.6 EGC34947.1 - 9.2e-12 43.9 9.3 0.0033 17.2 0.1 5.1 5 1 1 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EGC34947.1 - 1.4e-11 44.0 8.7 5.8e-05 22.9 0.0 4.1 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_4 PF12763.7 EGC34947.1 - 0.00027 20.8 2.8 0.0057 16.6 0.3 2.5 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.9 EGC34947.1 - 0.032 14.5 2.9 0.36 11.1 0.1 3.3 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region DUF2666 PF10869.8 EGC34947.1 - 0.037 14.2 4.5 0.21 11.8 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2666) NUDE_C PF04880.13 EGC34948.1 - 1.4e-06 28.9 10.3 1.4e-06 28.9 10.3 3.0 1 1 2 3 3 3 1 NUDE protein, C-terminal conserved region Spc7 PF08317.11 EGC34948.1 - 0.00013 21.0 32.2 0.0019 17.2 14.9 2.2 1 1 0 2 2 2 2 Spc7 kinetochore protein DUF5082 PF16888.5 EGC34948.1 - 0.00064 20.0 26.7 0.024 14.9 13.5 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF5082) WEMBL PF05701.11 EGC34948.1 - 0.0026 16.5 21.5 0.0039 16.0 21.5 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IFT57 PF10498.9 EGC34948.1 - 0.0041 16.1 25.3 0.014 14.4 15.9 2.2 1 1 1 2 2 2 2 Intra-flagellar transport protein 57 Bacillus_HBL PF05791.11 EGC34948.1 - 0.016 15.1 5.8 0.015 15.1 3.1 2.3 2 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) TPR_MLP1_2 PF07926.12 EGC34948.1 - 0.023 14.8 32.7 0.12 12.5 7.4 3.6 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein ZapB PF06005.12 EGC34948.1 - 0.038 14.4 7.9 0.038 14.4 7.9 4.5 2 1 1 4 4 3 0 Cell division protein ZapB BORCS8 PF10167.9 EGC34948.1 - 0.043 13.7 1.1 0.043 13.7 1.1 2.4 1 1 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Golgin_A5 PF09787.9 EGC34948.1 - 0.056 12.9 35.6 0.024 14.1 17.2 2.3 1 1 1 2 2 2 0 Golgin subfamily A member 5 NPV_P10 PF05531.12 EGC34948.1 - 0.4 11.2 14.2 6.6 7.3 0.1 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.12 EGC34948.1 - 0.43 10.6 13.4 2 8.5 0.3 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2203 PF09969.9 EGC34948.1 - 0.51 11.1 17.9 1.1 10.1 1.1 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) Lebercilin PF15619.6 EGC34948.1 - 0.58 9.8 33.4 0.54 9.9 19.9 2.5 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Serine_rich PF08824.10 EGC34948.1 - 0.66 10.0 15.4 31 4.5 14.7 2.7 1 1 1 2 2 2 0 Serine rich protein interaction domain GAS PF13851.6 EGC34948.1 - 0.84 9.0 29.8 6.9 6.0 24.4 2.0 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding ATG16 PF08614.11 EGC34948.1 - 1.5 9.0 41.3 0.27 11.4 22.2 3.6 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) YabA PF06156.13 EGC34948.1 - 2.2 9.0 22.1 1.1 9.9 5.4 3.5 1 1 2 3 3 3 0 Initiation control protein YabA Uds1 PF15456.6 EGC34948.1 - 2.6 8.2 28.8 0.39 10.9 3.7 3.3 1 1 2 3 3 3 0 Up-regulated During Septation DUF3584 PF12128.8 EGC34948.1 - 3 5.2 29.3 9.9 3.5 29.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.13 EGC34948.1 - 4 6.6 21.5 0.22 10.7 8.0 2.3 1 1 1 2 2 2 0 TMPIT-like protein APG6_N PF17675.1 EGC34948.1 - 4.4 7.8 34.5 7.6e+02 0.6 34.3 2.6 1 1 0 1 1 1 0 Apg6 coiled-coil region Cep57_MT_bd PF06657.13 EGC34948.1 - 5.6 7.5 25.1 0.35 11.4 4.7 4.0 1 1 3 4 4 4 0 Centrosome microtubule-binding domain of Cep57 ERM PF00769.19 EGC34948.1 - 7.7 6.3 35.4 14 5.4 28.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family UPF0242 PF06785.11 EGC34948.1 - 8.5 6.4 35.7 9.2 6.3 10.1 2.7 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus DUF3450 PF11932.8 EGC34948.1 - 8.8 5.6 24.8 0.15 11.3 10.0 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF3450) Fib_alpha PF08702.10 EGC34948.1 - 9.2 6.5 25.0 2.1 8.5 2.8 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_6 PF13405.6 EGC34949.1 - 5.6e-16 57.0 6.2 0.00039 20.1 0.2 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC34949.1 - 6e-14 50.5 7.1 0.00052 19.4 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC34949.1 - 7.4e-14 52.0 7.1 1.9e-08 34.6 1.0 2.4 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC34949.1 - 4.2e-07 30.3 4.1 0.00098 19.4 0.7 3.0 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.6 EGC34949.1 - 3.5e-05 23.1 5.3 0.057 12.9 0.1 3.8 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.6 EGC34949.1 - 0.0013 18.5 0.5 0.61 10.0 0.0 2.5 2 1 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC34949.1 - 0.0037 17.1 3.8 0.075 12.9 0.2 3.2 2 1 1 3 3 3 2 EF-hand domain pair Caleosin PF05042.13 EGC34949.1 - 0.016 15.1 1.2 6.7 6.6 0.1 3.5 1 1 3 4 4 4 0 Caleosin related protein DUF2624 PF11116.8 EGC34949.1 - 0.092 13.6 2.1 1.4 9.9 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Dockerin_1 PF00404.18 EGC34949.1 - 1.3 9.3 6.6 42 4.4 3.5 3.1 3 1 0 3 3 3 0 Dockerin type I domain EF-hand_1 PF00036.32 EGC34950.1 - 6.5e-20 69.1 8.3 0.00048 19.5 0.3 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.6 EGC34950.1 - 9.1e-19 65.7 8.4 0.00016 21.3 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.6 EGC34950.1 - 1.4e-16 60.7 13.6 5.6e-10 39.5 2.3 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.6 EGC34950.1 - 2.9e-10 39.8 10.9 3.6e-05 23.5 3.6 4.0 3 1 1 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.6 EGC34950.1 - 3e-09 36.0 7.3 0.0066 15.9 0.1 4.4 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.9 EGC34950.1 - 3.6e-09 36.9 4.8 7.3e-05 23.1 1.1 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3811 PF11656.8 EGC34950.1 - 0.0027 18.0 3.8 1.1 9.6 0.1 2.4 2 1 0 2 2 2 2 YjbD family (DUF3811) Caleosin PF05042.13 EGC34950.1 - 0.022 14.7 2.4 0.27 11.1 0.1 3.1 1 1 3 4 4 4 0 Caleosin related protein DUF2624 PF11116.8 EGC34950.1 - 0.042 14.7 1.7 0.076 13.9 0.3 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2624) RsbRD_N PF14361.6 EGC34950.1 - 0.099 13.3 0.2 0.22 12.3 0.2 1.5 1 0 0 1 1 1 0 RsbT co-antagonist protein rsbRD N-terminal domain DUF2267 PF10025.9 EGC34950.1 - 0.099 12.9 0.1 0.17 12.2 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2267) pP_pnuc_1 PF18165.1 EGC34950.1 - 0.2 11.5 3.6 0.099 12.5 0.9 1.8 2 0 0 2 2 2 0 Predicted pPIWI-associating nuclease DUF1103 PF06513.11 EGC34950.1 - 0.36 10.4 8.7 0.86 9.2 8.7 1.6 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) LMBR1 PF04791.16 EGC34951.1 - 2.5e-74 251.0 39.9 4.5e-73 246.9 23.0 4.0 2 1 1 3 3 3 2 LMBR1-like membrane protein DUF997 PF06196.12 EGC34951.1 - 1 9.4 4.3 5.5 7.1 0.2 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF997) PEPCK_GTP PF00821.18 EGC34952.1 - 4.5e-170 565.2 0.6 6.6e-170 564.7 0.6 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain PEPCK_N PF17297.2 EGC34952.1 - 1.8e-105 351.3 0.0 2.5e-105 350.9 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase N-terminal domain PEPCK_ATP PF01293.20 EGC34952.1 - 0.0082 14.9 0.0 0.012 14.3 0.0 1.2 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase DUF1285 PF06938.11 EGC34952.1 - 0.028 14.5 0.0 0.053 13.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) Mito_carr PF00153.27 EGC34953.1 - 1.5e-57 191.5 3.3 2.1e-19 69.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein SH3_9 PF14604.6 EGC34954.1 - 1.3e-14 53.8 0.1 2.7e-14 52.7 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.23 EGC34954.1 - 6.7e-13 48.7 0.2 6.7e-13 48.7 0.2 2.6 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.28 EGC34954.1 - 2e-12 46.5 0.1 3.6e-12 45.7 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGC34954.1 - 1.5e-10 40.6 0.0 3e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.16 EGC34954.1 - 7.6e-06 26.0 3.8 7.6e-06 26.0 3.8 2.9 3 0 0 3 3 3 1 Hr1 repeat GAS PF13851.6 EGC34954.1 - 0.001 18.5 19.1 0.0019 17.6 3.4 2.3 2 0 0 2 2 2 2 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.12 EGC34954.1 - 0.11 12.5 16.9 1.2 9.2 4.3 2.6 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Nbl1_Borealin_N PF10444.9 EGC34954.1 - 0.29 10.8 2.1 4.7 6.9 0.1 2.8 2 0 0 2 2 2 0 Nbl1 / Borealin N terminal PCRF PF03462.18 EGC34954.1 - 0.68 9.8 14.0 1.3 8.8 2.7 2.5 2 0 0 2 2 2 0 PCRF domain PmbA_TldD PF01523.16 EGC34954.1 - 0.98 9.2 5.3 3.2 7.5 0.0 2.8 2 1 0 2 2 2 0 Putative modulator of DNA gyrase DIT1_PvcA PF05141.12 EGC34954.1 - 1.4 8.3 7.3 0.26 10.7 2.4 1.9 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein DUF1664 PF07889.12 EGC34954.1 - 1.8 8.6 14.4 4.5 7.3 0.5 3.5 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) ANAPC15 PF15243.6 EGC34954.1 - 6.4 7.2 10.6 1.5 9.3 2.3 3.2 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 15 AAA_11 PF13086.6 EGC34954.1 - 6.8 6.4 11.0 5.3 6.7 1.0 2.1 2 0 0 2 2 2 0 AAA domain RasGAP PF00616.19 EGC34955.1 - 1.1e-31 110.2 0.0 5.6e-31 107.9 0.0 2.4 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.6 EGC34955.1 - 1e-17 64.6 2.5 2.4e-17 63.4 2.5 1.6 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGC34955.1 - 1.9e-13 50.5 1.9 4.3e-13 49.3 1.9 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.13 EGC34955.1 - 1.7e-07 31.1 5.9 0.0011 18.7 0.3 2.5 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding PRP38 PF03371.15 EGC34955.1 - 0.024 14.5 0.0 0.073 12.9 0.0 1.8 1 0 0 1 1 1 0 PRP38 family Peptidase_M73 PF12389.8 EGC34955.1 - 0.47 10.3 4.6 0.14 11.9 1.3 1.9 2 0 0 2 2 2 0 Camelysin metallo-endopeptidase Ras PF00071.22 EGC34956.1 - 1.7e-60 203.3 1.1 2e-60 203.1 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC34956.1 - 4.8e-36 123.6 0.2 4.8e-36 123.6 0.2 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC34956.1 - 3.7e-18 65.6 0.8 5e-18 65.1 0.8 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC34956.1 - 8.1e-09 35.2 1.2 1e-08 34.8 1.2 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC34956.1 - 5.9e-08 32.8 1.5 2.4e-07 30.8 0.1 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC34956.1 - 2.1e-07 30.7 0.5 4.4e-07 29.6 0.4 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC34956.1 - 5.8e-07 29.6 2.6 0.011 15.7 0.1 2.3 1 1 1 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGC34956.1 - 6.4e-06 25.7 0.2 0.00013 21.5 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGC34956.1 - 1.1e-05 25.0 0.4 3.6e-05 23.3 0.4 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B CPT PF07931.12 EGC34956.1 - 0.005 16.7 0.0 0.011 15.6 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.6 EGC34956.1 - 0.0073 16.6 0.1 0.033 14.4 0.1 2.2 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.9 EGC34956.1 - 0.018 14.8 0.4 1.3 8.8 0.4 2.8 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.6 EGC34956.1 - 0.023 15.1 0.1 0.039 14.3 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGC34956.1 - 0.033 13.9 2.5 0.54 9.9 2.5 2.3 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGC34956.1 - 0.053 12.9 0.2 0.32 10.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial TniB protein AAA_5 PF07728.14 EGC34956.1 - 0.08 12.9 0.1 0.14 12.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.6 EGC34956.1 - 0.083 12.7 0.0 0.33 10.7 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGC34956.1 - 0.13 11.8 0.0 0.13 11.8 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region AAA_23 PF13476.6 EGC34956.1 - 0.19 12.2 3.1 0.35 11.4 3.1 1.5 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.27 EGC34956.1 - 0.57 10.7 5.5 7 7.2 5.5 2.2 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.32 EGC34957.1 - 2.3e-45 151.6 8.3 6.2e-06 26.9 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC34957.1 - 7.6e-13 48.6 0.1 0.017 15.4 0.1 5.7 3 3 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC34957.1 - 9e-05 21.6 0.0 2.6 6.9 0.0 4.1 2 2 1 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGC34957.1 - 0.05 11.9 0.0 0.66 8.2 0.0 2.1 1 1 0 2 2 2 0 WD repeat-containing and planar cell polarity effector protein Fritz TetM_leader PF08076.11 EGC34957.1 - 2.3 8.1 6.4 66 3.4 0.2 4.2 4 0 0 4 4 4 0 Tetracycline resistance determinant leader peptide Amino_oxidase PF01593.24 EGC34958.1 - 8.7e-50 170.3 0.0 1.2e-49 169.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC34958.1 - 5e-13 49.1 0.0 9.9e-13 48.1 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.24 EGC34958.1 - 8.1e-05 21.9 0.0 0.00012 21.3 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGC34958.1 - 0.00032 20.4 0.0 0.0006 19.5 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGC34958.1 - 0.00041 19.7 2.6 0.00048 19.5 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGC34958.1 - 0.0041 16.3 0.0 0.02 14.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.14 EGC34958.1 - 0.0052 15.5 0.0 0.045 12.5 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_2 PF07992.14 EGC34958.1 - 0.0079 15.5 0.0 0.019 14.2 0.0 1.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC34958.1 - 0.013 16.1 0.2 0.14 12.7 0.0 2.5 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC34958.1 - 0.016 14.4 0.0 0.033 13.4 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Lycopene_cycl PF05834.12 EGC34958.1 - 0.056 12.5 0.0 7.7 5.4 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.7 EGC34958.1 - 0.15 11.3 0.1 0.32 10.3 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase DrrA_P4M PF14860.6 EGC34959.1 - 0.013 15.3 3.8 0.013 15.3 3.8 2.5 2 0 0 2 2 2 0 DrrA phosphatidylinositol 4-phosphate binding domain KH_5 PF13184.6 EGC34959.1 - 0.93 9.6 4.3 0.52 10.4 1.6 2.0 2 0 0 2 2 2 0 NusA-like KH domain IZUMO PF15005.6 EGC34959.1 - 3 8.3 8.4 3.7 8.1 4.1 2.5 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated FNIP PF05725.12 EGC34960.1 - 6.3e-08 32.7 11.0 1.4e-05 25.1 0.8 3.2 3 0 0 3 3 3 3 FNIP Repeat PA14 PF07691.12 EGC34961.1 - 1.3e-14 54.2 0.5 2.3e-14 53.4 0.5 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC34961.1 - 0.0031 17.4 4.9 0.0031 17.4 4.9 11.8 13 2 1 15 15 15 2 Dictyostelium (slime mold) repeat SURF2 PF05477.11 EGC34962.1 - 1.2e-18 67.7 45.9 1.2e-18 67.7 45.9 2.5 1 1 1 2 2 2 1 Surfeit locus protein 2 (SURF2) ChaB PF06150.12 EGC34963.1 - 1.5e-24 86.4 1.5 1.8e-24 86.1 1.5 1.1 1 0 0 1 1 1 1 ChaB Sec5 PF15469.6 EGC34963.1 - 0.011 15.6 0.1 0.011 15.5 0.1 1.0 1 0 0 1 1 1 0 Exocyst complex component Sec5 E1-E2_ATPase PF00122.20 EGC34964.1 - 1.1e-38 132.6 1.8 2.7e-38 131.3 0.5 2.3 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGC34964.1 - 4.3e-16 59.2 10.4 4.3e-16 59.2 10.4 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.26 EGC34964.1 - 1.3e-15 58.3 0.3 9.6e-15 55.4 0.3 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC34964.1 - 7.2e-14 51.2 0.0 4.9e-13 48.6 0.0 2.4 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGC34964.1 - 3.4e-05 23.8 0.0 7.5e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) HAD PF12710.7 EGC34964.1 - 8.4e-05 23.0 0.1 0.011 16.1 0.0 2.3 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC34964.1 - 0.017 14.9 0.4 0.29 10.8 0.1 2.7 3 0 0 3 3 3 0 haloacid dehalogenase-like hydrolase PIRT PF15099.6 EGC34964.1 - 0.35 10.4 2.1 0.42 10.2 0.3 2.1 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family FNIP PF05725.12 EGC34965.1 - 7.2e-23 80.5 73.4 5.6e-06 26.4 1.2 12.3 7 4 5 12 12 12 10 FNIP Repeat MFS_1 PF07690.16 EGC34966.1 - 1.3e-07 30.9 44.5 2.9e-07 29.8 13.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.16 EGC34966.1 - 3.1e-05 23.7 7.4 3.1e-05 23.7 7.4 3.4 2 1 0 3 3 3 1 Ion channel regulatory protein UNC-93 Tmemb_14 PF03647.13 EGC34966.1 - 0.0011 19.6 1.7 0.0011 19.6 1.7 4.4 3 1 0 3 3 3 1 Transmembrane proteins 14C DUF3586 PF12131.8 EGC34967.1 - 0.015 15.5 10.6 0.02 15.1 0.3 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) Peptidase_C71 PF12386.8 EGC34967.1 - 3.7 7.2 6.9 2.7 7.6 0.9 2.3 1 1 1 2 2 2 0 Pseudomurein endo-isopeptidase Pei YajC PF02699.15 EGC34968.1 - 0.045 13.6 0.1 0.23 11.4 0.1 2.2 1 0 0 1 1 1 0 Preprotein translocase subunit UPF0172 PF03665.13 EGC34969.1 - 1.1e-37 129.9 0.0 1.2e-37 129.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.21 EGC34969.1 - 3.6e-05 23.7 0.0 5.5e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SAPS PF04499.15 EGC34970.1 - 2.3e-76 257.5 4.0 3.2e-48 164.7 0.7 3.3 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein CS PF04969.16 EGC34971.1 - 3e-09 37.8 0.3 4.6e-09 37.2 0.3 1.3 1 0 0 1 1 1 1 CS domain Adaptin_binding PF10199.9 EGC34972.1 - 3.4e-22 79.3 16.2 3.4e-22 79.3 16.2 2.2 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 BESS PF02944.20 EGC34972.1 - 0.027 14.3 0.3 0.056 13.3 0.3 1.6 1 0 0 1 1 1 0 BESS motif Pex24p PF06398.11 EGC34972.1 - 0.81 8.6 6.0 1.6 7.6 5.5 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin F5_F8_type_C PF00754.25 EGC34973.1 - 3.5e-23 82.1 1.4 5.8e-23 81.4 1.4 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC34973.1 - 8.6e-14 51.5 0.5 2.4e-13 50.0 0.5 1.8 1 0 0 1 1 1 1 H-type lectin domain DUF4094 PF13334.6 EGC34974.1 - 0.0039 17.6 0.1 0.0088 16.4 0.1 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) ABC2_membrane_3 PF12698.7 EGC34974.1 - 0.076 12.1 0.2 0.086 11.9 0.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF1980 PF09323.10 EGC34974.1 - 2.6 7.9 6.7 0.21 11.5 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) FNIP PF05725.12 EGC34975.1 - 3.4e-99 324.8 41.8 1.6e-14 53.7 1.5 9.1 6 2 2 9 9 9 9 FNIP Repeat MCM_OB PF17207.3 EGC34975.1 - 0.002 18.0 0.2 90 2.9 0.0 5.4 3 2 6 9 9 9 0 MCM OB domain Vac14_Fab1_bd PF12755.7 EGC34976.1 - 0.0071 16.9 2.8 0.025 15.2 0.2 3.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Ribosomal_L4 PF00573.22 EGC34977.1 - 8.7e-39 133.2 0.9 8.7e-39 133.2 0.9 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.6 EGC34977.1 - 1.4e-24 85.9 7.2 2.3e-23 82.1 2.3 2.8 2 1 1 3 3 3 2 60S ribosomal protein L4 C-terminal domain Cadherin_2 PF08266.12 EGC34977.1 - 0.18 11.7 0.1 0.37 10.6 0.1 1.4 1 0 0 1 1 1 0 Cadherin-like Csc2 PF18320.1 EGC34978.1 - 0.02 13.9 0.7 0.033 13.2 0.7 1.3 1 0 0 1 1 1 0 Csc2 Crispr WRC PF08879.10 EGC34979.1 - 0.12 12.1 0.1 0.12 12.1 0.1 4.3 3 2 2 5 5 5 0 WRC ArfGap PF01412.18 EGC34980.1 - 7.2e-32 109.9 0.1 7.2e-32 109.9 0.1 3.1 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf VPS9 PF02204.18 EGC34981.1 - 3e-21 75.6 0.4 8.7e-21 74.1 0.1 2.0 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RNase_PH PF01138.21 EGC34981.1 - 1.7 9.1 6.3 0.46 11.0 0.1 3.0 3 0 0 3 3 3 0 3' exoribonuclease family, domain 1 Proteasome PF00227.26 EGC34983.1 - 6.3e-44 149.7 0.1 7.3e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.32 EGC34984.1 - 1.8e-22 77.2 12.2 1.9e-07 30.2 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC34984.1 - 6.4e-22 77.8 8.6 4.8e-12 46.2 1.6 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC34984.1 - 2.5e-20 70.6 8.2 1.1e-05 25.0 0.0 4.5 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC34984.1 - 1.5e-18 65.3 11.8 3e-06 26.5 0.3 4.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.6 EGC34984.1 - 1.3e-13 50.5 11.2 1.7e-05 24.6 1.6 3.8 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC34984.1 - 7e-05 23.1 1.2 0.38 11.1 0.2 3.2 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGC34984.1 - 0.00066 20.0 0.1 0.11 12.8 0.0 3.0 2 1 1 3 3 3 1 EF-hand domain EF-hand_2 PF09068.11 EGC34984.1 - 0.0045 17.1 0.1 0.048 13.8 0.0 2.3 2 1 0 2 2 2 1 EF hand Caleosin PF05042.13 EGC34984.1 - 0.0067 16.4 3.4 2 8.3 0.0 3.7 1 1 3 4 4 4 1 Caleosin related protein FNIP PF05725.12 EGC34986.1 - 8.2e-123 400.4 69.6 1.7e-13 50.5 0.3 12.0 11 2 1 12 12 12 11 FNIP Repeat Phage_min_tail PF05939.13 EGC34986.1 - 0.0017 18.7 0.0 20 5.6 0.0 6.2 7 2 2 9 9 9 1 Phage minor tail protein Sec23_trunk PF04811.15 EGC34988.1 - 7.3e-39 133.8 0.1 1.2e-38 133.1 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGC34988.1 - 1e-19 70.3 0.1 2.1e-19 69.2 0.1 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.12 EGC34988.1 - 9.1e-19 68.0 0.1 1.8e-18 67.0 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.15 EGC34988.1 - 3.3e-12 46.3 5.6 9.2e-12 44.8 5.6 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGC34988.1 - 0.00084 19.2 0.1 0.0024 17.7 0.1 1.8 1 0 0 1 1 1 1 Gelsolin repeat CRAL_TRIO PF00650.20 EGC34988.1 - 0.0052 16.5 0.1 0.89 9.3 0.0 2.4 2 0 0 2 2 2 2 CRAL/TRIO domain GTP1_OBG PF01018.22 EGC34989.1 - 9.1e-42 142.3 8.0 4.5e-28 97.8 4.5 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.23 EGC34989.1 - 4.4e-17 62.2 0.1 1.1e-16 61.0 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC34989.1 - 6.3e-06 25.8 0.7 0.054 13.0 0.1 3.0 2 1 1 3 3 3 2 Ferrous iron transport protein B NOG1 PF06858.14 EGC34989.1 - 0.15 11.9 0.0 15 5.5 0.0 2.4 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) CCDC53 PF10152.9 EGC34990.1 - 0.031 14.7 7.4 0.04 14.3 7.4 1.3 1 0 0 1 1 1 0 Subunit CCDC53 of WASH complex Presenilin PF01080.17 EGC34990.1 - 0.039 12.7 2.8 0.037 12.8 2.8 1.1 1 0 0 1 1 1 0 Presenilin Ndc1_Nup PF09531.10 EGC34990.1 - 0.36 9.5 3.3 0.33 9.6 3.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup AIF_C PF14721.6 EGC34990.1 - 1.5 9.2 7.2 3.3 8.1 7.2 1.6 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Pex14_N PF04695.13 EGC34990.1 - 2.6 8.7 14.5 4.2 8.0 14.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.16 EGC34990.1 - 3.6 7.6 4.9 4.7 7.2 4.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Membralin PF09746.9 EGC34990.1 - 4.1 6.3 4.7 5 6.1 4.7 1.1 1 0 0 1 1 1 0 Tumour-associated protein DUF4175 PF13779.6 EGC34990.1 - 4.5 5.0 12.7 5.2 4.8 12.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) ALMT PF11744.8 EGC34990.1 - 5.3 5.7 6.9 6.4 5.5 6.9 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Dynamin_N PF00350.23 EGC34991.1 - 6.3e-21 75.1 2.3 1.1e-20 74.3 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.23 EGC34991.1 - 2.5e-06 27.6 0.1 1.5e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.6 EGC34991.1 - 0.0015 19.1 7.6 0.16 12.5 0.7 2.9 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGC34991.1 - 0.024 14.7 1.1 0.14 12.2 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.6 EGC34991.1 - 0.028 14.8 0.4 1.8 8.9 0.0 2.9 3 0 0 3 3 3 0 AAA ATPase domain Roc PF08477.13 EGC34991.1 - 0.079 13.2 0.0 0.31 11.2 0.0 2.1 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase AAA_29 PF13555.6 EGC34991.1 - 0.15 11.8 0.0 0.54 10.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGC34991.1 - 0.34 11.4 1.3 2.7 8.5 0.0 2.7 3 0 0 3 3 3 0 ABC transporter Vir_act_alpha_C PF10400.9 EGC34991.1 - 6.6 7.5 6.9 23 5.8 0.1 3.0 2 1 0 2 2 2 0 Virulence activator alpha C-term zf-CCHC PF00098.23 EGC34992.1 - 0.00081 19.4 1.0 0.0013 18.7 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-C2H2_10 PF16588.5 EGC34992.1 - 0.0014 18.4 1.1 0.0014 18.4 1.1 1.8 2 0 0 2 2 2 1 C2H2 zinc-finger ATG16 PF08614.11 EGC34992.1 - 0.0063 16.8 9.9 0.02 15.2 9.9 1.9 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) GAS PF13851.6 EGC34992.1 - 0.013 14.8 9.1 0.013 14.8 9.1 3.4 3 1 0 3 3 3 0 Growth-arrest specific micro-tubule binding Phi-29_GP4 PF05464.11 EGC34992.1 - 0.12 12.7 2.6 0.16 12.2 0.1 2.5 2 1 1 3 3 3 0 Phi-29-like late genes activator (early protein GP4) Cnn_1N PF07989.11 EGC34992.1 - 0.63 10.2 22.6 0.11 12.6 0.6 4.4 2 1 3 5 5 5 0 Centrosomin N-terminal motif 1 RMP PF14996.6 EGC34992.1 - 1.4 9.2 10.8 4.7 7.4 0.1 3.2 2 1 1 3 3 3 0 Retinal Maintenance Atg14 PF10186.9 EGC34992.1 - 2.6 7.1 12.1 5.5 6.0 12.1 1.6 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 Chromo PF00385.24 EGC34993.1 - 8.8e-07 28.7 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Kinesin PF00225.23 EGC34994.1 - 3.1e-84 282.7 0.3 3.5e-84 282.6 0.3 1.0 1 0 0 1 1 1 1 Kinesin motor domain Microtub_bd PF16796.5 EGC34994.1 - 1.4e-13 51.0 0.2 3e-13 50.0 0.2 1.5 1 0 0 1 1 1 1 Microtubule binding Syntaphilin PF15290.6 EGC34996.1 - 0.68 9.5 2.8 1 8.9 2.8 1.2 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Ubie_methyltran PF01209.18 EGC34998.1 - 5.6e-12 45.5 0.0 6.4e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGC34998.1 - 1.4e-10 41.7 0.0 1.9e-10 41.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC34998.1 - 4.5e-10 40.1 0.0 6.3e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC34998.1 - 7.4e-08 32.3 0.0 9.1e-08 32.0 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC34998.1 - 7.5e-05 23.4 0.0 0.00011 22.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain zf-C3HC4_3 PF13920.6 EGC34999.1 - 4.8e-07 29.5 6.2 7.4e-07 28.9 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC34999.1 - 1.4e-05 24.8 5.0 1.4e-05 24.8 5.0 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC34999.1 - 2.4e-05 24.1 11.4 0.00023 20.9 11.3 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC34999.1 - 0.00014 21.8 9.8 0.00031 20.7 9.8 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGC34999.1 - 0.0003 21.1 9.3 0.00079 19.7 9.4 1.7 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGC34999.1 - 0.0043 17.2 11.1 0.0083 16.3 4.6 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGC34999.1 - 0.0043 17.3 5.8 0.0092 16.2 5.8 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC34999.1 - 0.0054 16.6 7.5 0.012 15.4 7.5 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 MAP17 PF15807.5 EGC34999.1 - 0.0083 16.4 1.3 0.045 14.0 0.0 2.1 2 0 0 2 2 2 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DZR PF12773.7 EGC34999.1 - 0.015 15.3 4.9 0.028 14.4 4.9 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGC34999.1 - 0.022 15.0 1.5 0.059 13.6 1.5 1.7 1 0 0 1 1 1 0 zinc-ribbon RAWUL PF16207.5 EGC34999.1 - 0.024 15.3 0.3 0.044 14.4 0.3 1.4 1 0 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like zf-RING_4 PF14570.6 EGC34999.1 - 0.031 14.1 8.0 0.062 13.1 7.9 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Ac76 PF05814.11 EGC34999.1 - 0.039 14.0 2.6 0.067 13.2 2.6 1.4 1 0 0 1 1 1 0 Orf76 (Ac76) zf-RING_UBOX PF13445.6 EGC34999.1 - 0.045 13.8 12.7 2.1 8.5 12.0 3.0 1 1 1 2 2 2 0 RING-type zinc-finger MRAP PF15183.6 EGC34999.1 - 0.054 13.4 0.3 0.12 12.3 0.3 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF3021 PF11457.8 EGC34999.1 - 0.14 12.5 3.2 0.19 12.1 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) CRA PF06589.11 EGC34999.1 - 1.4 9.0 6.7 6.4 6.9 6.7 1.8 1 1 0 1 1 1 0 Circumsporozoite-related antigen (CRA) zf-RING_6 PF14835.6 EGC34999.1 - 1.8 8.5 5.2 6.8 6.6 5.2 1.9 1 1 0 1 1 1 0 zf-RING of BARD1-type protein OppC_N PF12911.7 EGC34999.1 - 1.9 8.5 5.4 3.6 7.6 5.4 1.6 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C TIG PF01833.24 EGC35001.1 - 4.2e-115 376.1 117.3 9.1e-13 48.1 0.5 17.4 15 1 1 16 16 16 14 IPT/TIG domain PRKCSH_1 PF13015.6 EGC35001.1 - 0.099 12.3 8.5 0.88 9.2 0.1 4.3 4 0 0 4 4 4 0 Glucosidase II beta subunit-like protein DNase_II PF03265.15 EGC35002.1 - 2.7e-32 112.3 17.2 1.9e-25 89.9 10.2 2.1 1 1 0 2 2 2 2 Deoxyribonuclease II Snf7 PF03357.21 EGC35003.1 - 1.2e-15 57.5 15.0 1.2e-15 57.5 15.0 1.4 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.14 EGC35003.1 - 1.6e-06 28.1 6.1 2.5e-06 27.5 6.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway SAS4 PF15460.6 EGC35003.1 - 0.027 14.6 0.4 0.027 14.6 0.4 2.9 2 1 1 3 3 3 0 Something about silencing, SAS, complex subunit 4 KELK PF15796.5 EGC35003.1 - 3.5 8.2 14.4 5.4 7.5 4.7 3.2 3 0 0 3 3 3 0 KELK-motif containing domain of MRCK Ser/Thr protein kinase ABC2_membrane_3 PF12698.7 EGC35003.1 - 6.8 5.7 6.9 11 5.1 6.9 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein zf-RING_2 PF13639.6 EGC35004.1 - 3.5e-09 36.8 11.6 1.2e-08 35.1 11.6 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC35004.1 - 1.4e-07 31.3 10.2 2.9e-07 30.2 10.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC35004.1 - 2.6e-07 30.4 8.1 5.5e-07 29.4 8.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35004.1 - 8.9e-07 28.7 13.7 8.9e-07 28.7 13.7 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC35004.1 - 4.5e-05 23.4 6.0 0.00012 22.0 6.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC35004.1 - 0.00042 20.5 11.0 0.0025 18.0 11.0 2.4 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC35004.1 - 0.0095 15.9 11.1 0.024 14.6 11.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC35004.1 - 0.012 15.5 6.9 0.033 14.0 6.9 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC35004.1 - 0.019 15.1 10.0 0.052 13.7 10.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC35004.1 - 0.034 13.9 9.0 0.082 12.7 9.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF4083 PF13314.6 EGC35004.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) zf-RING_10 PF16685.5 EGC35004.1 - 0.084 13.0 4.1 0.21 11.7 4.1 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC35004.1 - 0.14 12.2 5.6 0.74 9.9 5.6 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC35004.1 - 0.41 10.4 10.0 1.1 9.0 10.0 1.8 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGC35004.1 - 1 9.5 6.6 2.6 8.2 6.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Brr6_like_C_C PF10104.9 EGC35009.1 - 1.1e-08 34.9 0.4 2.1e-08 34.0 0.4 1.5 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF4834 PF16118.5 EGC35009.1 - 0.024 15.6 2.1 15 6.6 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Secretin_N_2 PF07655.13 EGC35009.1 - 0.028 14.9 9.4 0.047 14.2 9.4 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF747 PF05346.11 EGC35009.1 - 0.04 13.4 0.7 0.053 13.0 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic membrane protein family Apis_Csd PF11671.8 EGC35009.1 - 3 7.8 18.0 7 6.7 18.0 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein CH PF00307.31 EGC35011.1 - 5.1e-51 171.4 4.0 9.5e-27 93.3 0.0 4.1 4 0 0 4 4 4 2 Calponin homology (CH) domain Spectrin PF00435.21 EGC35011.1 - 2.2e-31 108.4 28.0 1.2e-09 38.5 1.0 4.6 4 0 0 4 4 4 4 Spectrin repeat EF-hand_1 PF00036.32 EGC35011.1 - 1.1e-12 46.5 0.3 9.6e-06 24.8 0.0 3.1 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.6 EGC35011.1 - 3e-11 43.6 0.8 2.9e-10 40.4 0.8 2.9 1 0 0 1 1 1 1 EF-hand domain pair CAMSAP_CH PF11971.8 EGC35011.1 - 1.4e-10 40.9 0.1 8.9e-09 35.1 0.0 2.7 2 0 0 2 2 2 1 CAMSAP CH domain EFhand_Ca_insen PF08726.10 EGC35011.1 - 1.4e-10 41.1 0.4 5e-10 39.3 0.4 2.0 1 0 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_6 PF13405.6 EGC35011.1 - 2.6e-10 39.4 1.3 0.00049 19.8 0.1 4.2 4 0 0 4 4 3 2 EF-hand domain EF-hand_8 PF13833.6 EGC35011.1 - 4.5e-08 32.8 2.2 8.3e-07 28.8 0.4 3.0 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_5 PF13202.6 EGC35011.1 - 1e-05 24.8 6.8 0.0012 18.2 0.0 4.0 4 0 0 4 4 4 2 EF hand CH_2 PF06294.11 EGC35011.1 - 0.00059 19.9 0.2 5.7 7.1 0.0 4.2 4 0 0 4 4 4 2 CH-like domain in sperm protein EF-hand_4 PF12763.7 EGC35011.1 - 0.0093 15.9 0.1 0.077 13.0 0.1 2.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand Iron_permease PF04120.12 EGC35011.1 - 0.078 12.8 1.2 0.61 9.9 1.2 2.6 1 0 0 1 1 1 0 Low affinity iron permease Coiled PF05710.12 EGC35012.1 - 0.0074 17.1 16.3 0.013 16.3 16.3 1.5 1 1 0 1 1 1 1 Coiled coil Phage_CRI PF05144.14 EGC35012.1 - 0.19 11.0 0.7 0.21 10.9 0.7 1.3 1 1 0 1 1 1 0 Phage replication protein CRI Coiled PF05710.12 EGC35013.1 - 8.5e-07 29.7 9.6 1.1e-06 29.4 9.6 1.2 1 0 0 1 1 1 1 Coiled coil EMP70 PF02990.16 EGC35014.1 - 4.8e-44 150.9 34.4 9e-44 150.0 34.4 1.4 1 0 0 1 1 1 1 Endomembrane protein 70 DDHD PF02862.17 EGC35014.1 - 0.033 14.4 0.6 7.8 6.6 0.0 2.4 2 1 0 2 2 2 0 DDHD domain Adeno_E3_CR2 PF02439.15 EGC35014.1 - 3.2 7.6 9.1 5.8 6.8 0.7 3.2 2 0 0 2 2 2 0 Adenovirus E3 region protein CR2 UbiA PF01040.18 EGC35015.1 - 2.5e-17 63.0 13.9 3.7e-17 62.5 13.5 1.5 1 1 0 1 1 1 1 UbiA prenyltransferase family Cation_efflux PF01545.21 EGC35016.1 - 2.1e-47 161.5 11.6 2.9e-47 161.0 11.6 1.1 1 0 0 1 1 1 1 Cation efflux family ASH PF15780.5 EGC35017.1 - 1e-05 25.6 22.2 0.0013 18.9 0.2 10.1 10 1 0 10 10 10 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin PapD-like PF14874.6 EGC35017.1 - 0.0011 19.1 0.3 15 5.8 0.0 5.5 5 0 0 5 5 5 1 Flagellar-associated PapD-like TMEM131_like PF12371.8 EGC35017.1 - 0.0015 18.7 1.3 0.34 11.2 0.2 5.3 4 0 0 4 4 4 1 Transmembrane protein 131-like RRM_1 PF00076.22 EGC35018.1 - 6e-15 54.8 2.4 3e-08 33.4 0.2 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC35018.1 - 5.2e-08 32.8 0.6 0.00079 19.4 0.1 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RL PF17797.1 EGC35018.1 - 0.00072 19.5 2.5 0.0014 18.5 0.4 2.5 2 0 0 2 2 2 1 RL domain DUF885 PF05960.11 EGC35018.1 - 0.024 14.3 0.6 0.039 13.6 0.6 1.4 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) CLZ PF16526.5 EGC35018.1 - 8 6.9 11.4 4.7 7.7 4.3 3.7 3 1 1 4 4 4 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Nkap_C PF06047.11 EGC35019.1 - 1.9e-47 159.6 1.7 1.9e-47 159.6 1.7 3.4 3 0 0 3 3 3 1 NF-kappa-B-activating protein C-terminal domain Mucin PF01456.17 EGC35019.1 - 0.25 11.3 6.7 0.43 10.6 6.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3330 PF11809.8 EGC35020.1 - 0.21 11.6 2.0 0.47 10.5 2.0 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3330) Cornichon PF03311.14 EGC35021.1 - 3.4e-35 121.0 15.3 4e-35 120.8 15.3 1.1 1 0 0 1 1 1 1 Cornichon protein Arm PF00514.23 EGC35022.1 - 2.9e-41 138.3 0.6 1.3e-13 50.4 0.0 5.9 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGC35022.1 - 2.5e-13 50.2 0.0 5.5e-08 33.1 0.0 3.7 3 0 0 3 3 3 2 HEAT-like repeat HEAT_2 PF13646.6 EGC35022.1 - 6.9e-09 36.0 0.0 1.1e-05 25.8 0.0 4.0 3 1 1 5 5 5 2 HEAT repeats HEAT PF02985.22 EGC35022.1 - 1e-07 31.6 2.9 0.0069 16.5 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Atx10homo_assoc PF09759.9 EGC35022.1 - 0.012 15.6 9.4 0.14 12.2 0.1 3.8 2 2 2 4 4 4 0 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.8 EGC35022.1 - 0.077 12.9 3.2 0.37 10.7 0.0 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF3361) FPL PF09758.9 EGC35022.1 - 0.12 12.3 10.7 0.6 10.1 4.0 3.2 2 2 0 2 2 2 0 Uncharacterised conserved protein RCC1 PF00415.18 EGC35023.1 - 1.3e-64 214.6 13.1 2.2e-13 50.6 0.5 8.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC35023.1 - 6e-36 121.5 27.8 9.3e-08 31.7 0.1 7.5 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.19 EGC35023.1 - 2e-33 115.9 0.0 2e-33 115.9 0.0 5.1 4 2 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase RhoGEF PF00621.20 EGC35023.1 - 3.7e-24 86.0 2.7 3.7e-24 86.0 2.7 2.8 2 1 0 2 2 2 1 RhoGEF domain Uteroglobin PF01099.17 EGC35023.1 - 0.14 12.5 2.7 0.32 11.3 0.2 2.8 2 0 0 2 2 2 0 Uteroglobin family Borrelia_P83 PF05262.11 EGC35023.1 - 0.61 8.5 23.5 1.2 7.5 23.5 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein MMR_HSR1 PF01926.23 EGC35024.1 - 2.5e-18 66.2 0.0 5.8e-18 65.0 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC35024.1 - 1.2e-06 28.1 0.0 2.2e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC35024.1 - 2.2e-05 24.4 3.4 0.0011 18.8 0.0 2.9 3 0 0 3 3 3 2 RsgA GTPase Dynamin_N PF00350.23 EGC35024.1 - 6.2e-05 23.1 14.0 0.00038 20.5 0.0 4.1 3 1 1 4 4 4 2 Dynamin family GTP_EFTU PF00009.27 EGC35024.1 - 0.00032 20.3 0.1 0.06 12.9 0.3 2.6 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain AIG1 PF04548.16 EGC35024.1 - 0.00069 19.0 0.9 0.0022 17.3 0.9 1.9 1 1 0 1 1 1 1 AIG1 family PduV-EutP PF10662.9 EGC35024.1 - 0.013 15.3 0.1 0.39 10.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGC35024.1 - 0.069 13.7 0.0 0.069 13.7 0.0 2.6 3 0 0 3 3 3 0 ABC transporter PDEase_I PF00233.19 EGC35025.1 - 4.2e-69 232.9 7.9 4.2e-69 232.9 7.9 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase NAP PF00956.18 EGC35026.1 - 5.3e-64 216.0 2.7 7.3e-64 215.5 2.7 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.8 EGC35026.1 - 0.00025 21.1 2.8 0.00061 19.8 2.8 1.6 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 NuA4 PF09340.10 EGC35026.1 - 0.13 12.2 0.4 0.27 11.1 0.4 1.5 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 FNIP PF05725.12 EGC35027.1 - 3.9e-109 356.6 72.7 9.1e-15 54.6 0.2 11.4 6 3 5 12 12 12 11 FNIP Repeat Keratin_assoc PF09775.9 EGC35027.1 - 0.12 12.1 0.1 65 3.2 0.0 4.4 4 1 0 5 5 5 0 Keratinocyte-associated protein 2 FNIP PF05725.12 EGC35028.1 - 8.2e-21 73.9 15.0 1.3e-06 28.5 0.2 7.7 6 3 2 8 8 8 5 FNIP Repeat LRR_4 PF12799.7 EGC35028.1 - 4.9 7.7 8.8 8.3 7.0 0.1 4.1 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) Dak1 PF02733.17 EGC35029.1 - 2.5e-98 328.8 0.1 2.9e-97 325.3 0.1 2.0 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.17 EGC35029.1 - 2.4e-47 161.1 0.0 4e-47 160.4 0.0 1.4 1 0 0 1 1 1 1 DAK2 domain tRNA-synt_1g PF09334.11 EGC35029.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (M) RuvB_C PF05491.13 EGC35029.1 - 0.17 11.8 0.5 0.69 9.8 0.5 2.1 1 0 0 1 1 1 0 RuvB C-terminal winged helix domain ZapB PF06005.12 EGC35030.1 - 0.026 15.0 11.3 0.14 12.6 11.3 2.3 1 1 0 1 1 1 0 Cell division protein ZapB Proteasome PF00227.26 EGC35031.1 - 5.3e-21 75.0 0.0 1.2e-20 73.9 0.0 1.6 1 1 0 1 1 1 1 Proteasome subunit Pkinase_Tyr PF07714.17 EGC35032.1 - 3.3e-57 193.7 0.0 5.8e-57 192.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35032.1 - 1.6e-54 185.0 0.0 3.8e-54 183.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.19 EGC35032.1 - 4.9e-41 140.9 0.1 1.5e-40 139.3 0.1 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGC35032.1 - 1.6e-19 70.1 2.2 1.6e-19 70.1 2.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif Haspin_kinase PF12330.8 EGC35032.1 - 0.00024 20.2 0.0 0.00024 20.2 0.0 2.6 3 0 0 3 3 3 1 Haspin like kinase domain Kdo PF06293.14 EGC35032.1 - 0.012 15.0 0.0 0.024 14.0 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC35032.1 - 0.042 12.6 0.0 0.042 12.6 0.0 2.1 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EGC35032.1 - 0.1 12.5 0.0 0.21 11.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.12 EGC35033.1 - 1.1e-19 70.3 58.4 6e-12 45.5 2.3 11.1 7 4 4 12 12 12 8 FNIP Repeat HMA PF00403.26 EGC35034.1 - 0.012 16.0 0.1 0.03 14.8 0.1 1.7 1 0 0 1 1 1 0 Heavy-metal-associated domain Arm PF00514.23 EGC35034.1 - 0.044 13.9 0.0 0.14 12.2 0.0 1.9 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat RICTOR_M PF14666.6 EGC35034.1 - 0.045 13.5 0.9 0.1 12.4 0.4 1.8 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, middle domain BPL_N PF09825.9 EGC35034.1 - 0.11 11.5 2.7 0.14 11.2 2.7 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal LRRFIP PF09738.9 EGC35034.1 - 0.34 10.3 6.8 0.52 9.7 6.8 1.2 1 0 0 1 1 1 0 LRRFIP family L_HMGIC_fpl PF10242.9 EGC35035.1 - 0.00048 20.4 3.0 0.00074 19.8 3.0 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein PMP22_Claudin PF00822.20 EGC35035.1 - 0.021 14.7 8.5 0.013 15.4 4.9 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Bunya_G2 PF03563.13 EGC35035.1 - 0.027 13.7 2.1 0.038 13.3 2.1 1.2 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 Claudin_2 PF13903.6 EGC35035.1 - 0.032 14.0 0.7 0.032 14.0 0.7 2.9 1 1 3 4 4 4 0 PMP-22/EMP/MP20/Claudin tight junction Thioredoxin PF00085.20 EGC35037.1 - 2.1e-12 46.9 0.3 2.5e-12 46.7 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.6 EGC35037.1 - 0.0016 18.6 0.1 0.0023 18.1 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGC35037.1 - 0.0019 18.6 0.9 0.01 16.3 0.9 1.9 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC35037.1 - 0.012 15.9 2.4 0.055 13.8 2.4 2.1 1 1 0 1 1 1 0 Thioredoxin-like Thioredoxin_3 PF13192.6 EGC35037.1 - 0.013 15.5 0.1 0.023 14.7 0.1 1.4 1 1 0 1 1 1 0 Thioredoxin domain Ost5 PF05251.12 EGC35038.1 - 5e-21 74.7 7.6 5.6e-21 74.6 7.6 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit 5 CAAD PF14159.6 EGC35038.1 - 0.016 15.1 0.2 0.024 14.5 0.1 1.3 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase zf-met PF12874.7 EGC35039.1 - 0.14 12.6 0.7 0.55 10.7 0.7 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC35039.1 - 0.33 11.3 3.0 0.49 10.8 0.9 2.5 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding RhoGAP PF00620.27 EGC35040.1 - 6.8e-23 81.2 2.2 1.2e-22 80.3 0.4 2.3 2 0 0 2 2 2 1 RhoGAP domain PI_PP_C PF18365.1 EGC35040.1 - 0.044 13.8 0.8 0.25 11.3 0.0 2.6 3 0 0 3 3 3 0 Phosphoinositide phosphatase C-terminal domain PEPCK_GTP PF00821.18 EGC35040.1 - 0.051 12.4 0.0 0.11 11.3 0.0 1.5 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain ApoB100_C PF12491.8 EGC35040.1 - 0.069 13.1 0.0 0.27 11.2 0.0 2.1 1 0 0 1 1 1 0 Apolipoprotein B100 C terminal zf-C2H2 PF00096.26 EGC35043.1 - 2.5e-11 43.4 21.7 0.00018 21.8 4.0 4.0 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.6 EGC35043.1 - 0.00012 22.7 32.5 0.0067 17.2 4.1 4.5 4 1 0 4 4 3 3 C2H2-type zinc finger zf-H2C2_5 PF13909.6 EGC35043.1 - 0.00015 21.4 0.5 0.00015 21.4 0.5 5.5 5 0 0 5 5 5 1 C2H2-type zinc-finger domain zf-BED PF02892.15 EGC35043.1 - 0.0034 17.4 2.3 0.0034 17.4 2.3 3.9 4 0 0 4 4 4 1 BED zinc finger zf-C2H2_11 PF16622.5 EGC35043.1 - 0.0045 16.7 14.5 0.12 12.2 3.0 3.5 3 0 0 3 3 3 2 zinc-finger C2H2-type zf-met PF12874.7 EGC35043.1 - 0.0068 16.8 2.3 0.0068 16.8 2.3 3.5 4 0 0 4 4 4 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC35043.1 - 0.014 15.7 3.4 0.014 15.7 3.4 3.7 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding FOXP-CC PF16159.5 EGC35043.1 - 0.046 14.4 8.6 2.2 9.0 1.4 3.5 2 1 1 3 3 3 0 FOXP coiled-coil domain zf-C2H2_6 PF13912.6 EGC35043.1 - 1.2 9.2 17.4 1.3 9.1 4.6 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger zf-H2C2_2 PF13465.6 EGC35043.1 - 1.5 9.4 25.0 0.048 14.1 2.9 5.2 4 1 0 4 4 4 0 Zinc-finger double domain Zn-ribbon_8 PF09723.10 EGC35043.1 - 1.9 8.6 9.4 3.4 7.9 0.1 4.0 4 0 0 4 4 4 0 Zinc ribbon domain zf-MYST PF17772.1 EGC35043.1 - 3.2 7.4 7.8 0.61 9.7 0.4 2.5 2 0 0 2 2 2 0 MYST family zinc finger domain DNA_alkylation PF08713.11 EGC35044.1 - 3.3e-51 174.0 0.7 3.8e-51 173.8 0.7 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme Urotensin_II PF02083.15 EGC35044.1 - 0.065 12.9 0.9 0.21 11.3 0.9 1.9 1 0 0 1 1 1 0 Urotensin II ETRAMP PF09716.10 EGC35045.1 - 0.028 14.5 0.0 0.4 10.8 0.0 2.9 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Glyco_hydro_38N PF01074.22 EGC35047.1 - 7.9e-76 255.2 2.4 1.3e-75 254.4 2.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC35047.1 - 8.2e-22 77.2 0.2 1.9e-21 76.0 0.2 1.7 1 0 0 1 1 1 1 Alpha mannosidase middle domain G3P_antiterm PF04309.12 EGC35047.1 - 0.0013 18.1 0.0 0.015 14.7 0.1 2.4 3 0 0 3 3 3 1 Glycerol-3-phosphate responsive antiterminator Glyco_hydro_38 PF18438.1 EGC35047.1 - 0.047 13.8 0.0 0.2 11.7 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 38 C-terminal domain 1 Glyco_hydro_39 PF01229.17 EGC35048.1 - 5e-63 213.4 0.7 5.5e-63 213.2 0.7 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 L_HMGIC_fpl PF10242.9 EGC35049.1 - 0.1 12.8 0.6 0.23 11.7 0.1 1.8 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein Paf1 PF03985.13 EGC35050.1 - 0.002 17.2 20.4 0.0022 17.0 20.4 1.2 1 0 0 1 1 1 1 Paf1 SDA1 PF05285.12 EGC35050.1 - 0.38 10.1 28.1 0.54 9.6 28.1 1.3 1 0 0 1 1 1 0 SDA1 Tfb4 PF03850.14 EGC35050.1 - 9.1 5.7 8.5 0.24 10.9 1.1 1.9 1 1 1 2 2 2 0 Transcription factor Tfb4 DPBB_1 PF03330.18 EGC35051.1 - 0.048 13.9 0.6 0.72 10.2 0.6 2.6 1 1 0 1 1 1 0 Lytic transglycolase CBM_11 PF03425.13 EGC35051.1 - 0.096 12.6 1.3 0.32 10.9 0.8 2.1 2 1 0 2 2 2 0 Carbohydrate binding domain (family 11) Lyase_1 PF00206.20 EGC35052.1 - 6.2e-53 180.2 0.1 7.9e-53 179.9 0.1 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.11 EGC35052.1 - 1.4e-46 157.3 0.1 5.9e-46 155.3 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Peptidase_M16_C PF05193.21 EGC35053.1 - 2.4e-18 66.8 0.5 2.5e-12 47.2 0.0 3.5 3 0 0 3 3 3 3 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC35053.1 - 2.5e-09 37.3 0.0 2.3e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) NOA36 PF06524.12 EGC35053.1 - 0.0091 15.4 16.0 0.018 14.4 16.0 1.4 1 0 0 1 1 1 1 NOA36 protein DUF5347 PF17282.2 EGC35053.1 - 0.11 12.8 0.1 0.43 10.9 0.1 2.0 1 0 0 1 1 1 0 Family of unknown function (DUF5347) NFACT-R_1 PF05670.13 EGC35053.1 - 0.17 12.6 0.9 0.39 11.4 0.2 2.0 2 0 0 2 2 2 0 NFACT protein RNA binding domain Nop14 PF04147.12 EGC35053.1 - 0.27 9.4 26.2 0.58 8.3 26.2 1.4 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.12 EGC35053.1 - 0.88 8.5 8.7 0.44 9.5 5.7 2.0 3 0 0 3 3 3 0 Domain of Unknown Function (DUF913) SDA1 PF05285.12 EGC35053.1 - 0.88 8.9 23.1 1.9 7.9 23.1 1.4 1 0 0 1 1 1 0 SDA1 Astro_capsid_p PF12226.8 EGC35053.1 - 1.9 7.6 18.4 3.6 6.6 18.4 1.4 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CDC45 PF02724.14 EGC35053.1 - 2.1 6.6 17.5 3.2 5.9 17.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Peptidase_C37 PF05416.12 EGC35053.1 - 2.6 6.5 5.2 4.2 5.8 5.2 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase RNA_pol_Rpc4 PF05132.14 EGC35053.1 - 3.9 7.9 7.5 4.5 7.7 6.0 1.8 2 0 0 2 2 2 0 RNA polymerase III RPC4 Zip PF02535.22 EGC35053.1 - 5.1 6.2 5.9 8.2 5.5 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter CPSF100_C PF13299.6 EGC35053.1 - 6.2 7.0 8.8 15 5.8 8.8 1.5 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TRAP_alpha PF03896.16 EGC35053.1 - 8.5 5.5 15.7 62 2.6 0.0 2.6 3 0 0 3 3 3 0 Translocon-associated protein (TRAP), alpha subunit BUD22 PF09073.10 EGC35053.1 - 9.5 5.4 24.4 0.079 12.3 16.4 1.5 2 0 0 2 2 2 0 BUD22 DUF4507 PF14964.6 EGC35054.1 - 0.00027 20.0 4.6 0.22 10.4 0.1 2.7 2 1 0 2 2 2 2 Domain of unknown function (DUF4507) CBF PF03914.17 EGC35054.1 - 0.014 15.4 0.2 3.6 7.6 0.0 2.6 1 1 1 2 2 2 0 CBF/Mak21 family Fanconi_A PF03511.14 EGC35055.1 - 0.084 12.8 0.4 0.23 11.4 0.4 1.7 1 0 0 1 1 1 0 Fanconi anaemia group A protein WD40 PF00400.32 EGC35056.1 - 6.4e-29 99.6 11.4 6.4e-07 30.0 0.2 7.6 7 0 0 7 7 7 4 WD domain, G-beta repeat Striatin PF08232.12 EGC35056.1 - 2.7e-27 96.3 6.6 2.7e-27 96.3 6.6 4.9 2 2 1 3 3 3 1 Striatin family ANAPC4_WD40 PF12894.7 EGC35056.1 - 1.6e-10 41.2 0.0 0.0039 17.5 0.0 4.8 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Methyltransf_23 PF13489.6 EGC35056.1 - 0.019 14.8 0.9 0.047 13.5 0.9 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF4175 PF13779.6 EGC35056.1 - 0.77 7.6 18.7 1.2 7.0 18.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) MMPL PF03176.15 EGC35056.1 - 0.95 8.3 4.5 1.5 7.7 4.5 1.4 1 0 0 1 1 1 0 MMPL family Methyltransf_12 PF08242.12 EGC35056.1 - 4.1 8.2 6.4 19 6.1 1.7 3.6 3 0 0 3 3 3 0 Methyltransferase domain Lyase_aromatic PF00221.19 EGC35057.1 - 3.4e-188 626.1 0.0 3.9e-188 625.9 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Soyouz_module PF14313.6 EGC35057.1 - 0.014 15.1 0.1 0.045 13.5 0.1 1.8 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PPR_2 PF13041.6 EGC35059.1 - 1.2e-28 99.0 9.1 5.7e-07 29.6 0.0 6.7 5 2 2 7 7 7 6 PPR repeat family PPR_3 PF13812.6 EGC35059.1 - 1e-20 73.5 15.2 6.4e-05 22.9 0.1 5.6 5 1 0 5 5 5 4 Pentatricopeptide repeat domain PPR_long PF17177.4 EGC35059.1 - 1.6e-20 73.4 0.1 5.1e-10 39.1 0.0 3.0 1 1 1 3 3 3 3 Pentacotripeptide-repeat region of PRORP PPR PF01535.20 EGC35059.1 - 9.2e-17 60.1 6.2 5e-05 23.3 0.1 6.9 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.7 EGC35059.1 - 1.1e-07 31.4 9.2 0.068 12.9 0.0 6.7 7 0 0 7 7 7 2 PPR repeat RPM2 PF08579.11 EGC35059.1 - 0.00018 21.9 1.0 0.00018 21.9 1.0 4.3 3 1 2 5 5 5 1 Mitochondrial ribonuclease P subunit (RPM2) IFT81_CH PF18383.1 EGC35059.1 - 0.27 11.5 4.8 8.9 6.6 0.2 3.1 2 1 1 3 3 3 0 Intraflagellar transport 81 calponin homology domain SH2 PF00017.24 EGC35060.1 - 5.4e-14 52.1 0.0 2.6e-11 43.4 0.0 3.1 2 0 0 2 2 2 2 SH2 domain Cbl_N3 PF02762.14 EGC35060.1 - 0.096 12.6 0.1 2.8 7.9 0.1 2.8 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain DUF202 PF02656.15 EGC35061.1 - 1.4e-10 41.4 7.3 1.5e-10 41.4 5.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Menin PF05053.13 EGC35061.1 - 3.3 5.9 17.1 5.1 5.3 17.1 1.2 1 0 0 1 1 1 0 Menin P2X_receptor PF00864.19 EGC35062.1 - 1.4e-22 80.3 1.7 1.5e-10 40.7 0.0 2.5 2 1 1 3 3 3 2 ATP P2X receptor GFO_IDH_MocA PF01408.22 EGC35065.1 - 2.6e-24 86.3 0.0 3.8e-24 85.8 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.17 EGC35065.1 - 8.4e-06 25.8 0.0 1.6e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TPT PF03151.16 EGC35066.1 - 1.5e-58 198.5 33.1 1.8e-58 198.2 33.1 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGC35066.1 - 1.4e-15 57.6 41.6 2.9e-09 37.2 18.5 2.3 2 1 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGC35066.1 - 4.7e-07 29.3 32.5 6e-07 29.0 32.5 1.1 1 0 0 1 1 1 1 UAA transporter family UPF0060 PF02694.15 EGC35066.1 - 0.021 15.0 2.2 0.021 15.0 2.2 2.3 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family Phage_holin_2_4 PF16082.5 EGC35066.1 - 0.46 10.3 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Bacteriophage holin family, superfamily II-like Cyclin_N PF00134.23 EGC35067.1 - 0.032 14.0 3.0 0.1 12.3 1.8 2.3 2 1 0 2 2 2 0 Cyclin, N-terminal domain DUF3955 PF13127.6 EGC35067.1 - 0.046 13.6 0.2 0.12 12.2 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3955) RNA12 PF10443.9 EGC35068.1 - 5e-55 187.0 0.3 9.8e-28 97.1 0.1 2.8 1 1 1 2 2 2 2 RNA12 protein ATPase_2 PF01637.18 EGC35068.1 - 1.4e-06 28.4 0.6 2.9e-06 27.4 0.0 1.8 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea RRM_1 PF00076.22 EGC35068.1 - 0.0012 18.7 0.0 0.0095 15.7 0.0 2.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_35 PF14516.6 EGC35068.1 - 0.0023 16.8 0.0 0.0049 15.7 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain AAA_23 PF13476.6 EGC35068.1 - 0.0078 16.7 2.7 6.7 7.2 1.9 2.9 3 1 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGC35068.1 - 0.022 15.1 0.0 0.074 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.6 EGC35068.1 - 0.067 12.9 0.0 0.15 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC35068.1 - 0.15 12.3 0.0 0.38 11.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain EGF_CA PF07645.15 EGC35069.1 - 2.3e-22 78.9 40.5 1e-08 35.2 7.3 3.4 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 EGC35069.1 - 8.6e-21 73.9 46.5 3.2e-09 36.9 7.9 3.8 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGC35069.1 - 9.3e-16 57.4 32.2 1.5e-07 31.2 1.5 5.1 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.7 EGC35069.1 - 2.6e-06 27.5 31.8 0.0087 16.2 5.4 3.9 3 1 0 3 3 3 3 EGF domain hEGF PF12661.7 EGC35069.1 - 1.1e-05 25.8 27.3 0.0016 19.0 1.5 4.4 3 1 0 3 3 3 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.7 EGC35069.1 - 0.0067 16.5 19.0 0.0086 16.1 0.5 3.6 3 0 0 3 3 3 2 MSP1 EGF domain 1 EGF PF00008.27 EGC35069.1 - 0.082 13.2 35.2 0.62 10.4 8.2 3.6 3 0 0 3 3 3 0 EGF-like domain IKI3 PF04762.12 EGC35070.1 - 1.9e-275 916.5 2.2 3e-275 915.8 2.2 1.3 1 0 0 1 1 1 1 IKI3 family ANAPC4_WD40 PF12894.7 EGC35070.1 - 3.5e-07 30.4 0.3 0.021 15.1 0.0 4.8 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain TFIIIC_delta PF12657.7 EGC35070.1 - 0.019 14.9 2.0 1 9.3 0.2 3.6 3 0 0 3 3 3 0 Transcription factor IIIC subunit delta N-term Clathrin PF00637.20 EGC35070.1 - 0.22 11.4 12.1 1.4 8.8 0.6 4.7 3 2 1 4 4 4 0 Region in Clathrin and VPS adh_short PF00106.25 EGC35072.1 - 1.6e-48 164.7 0.0 2e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC35072.1 - 1.4e-35 123.0 0.0 1.7e-35 122.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC35072.1 - 8.4e-09 35.6 0.0 1.7e-08 34.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGC35072.1 - 0.005 16.7 0.0 0.0078 16.1 0.0 1.5 1 1 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC35072.1 - 0.01 15.3 0.0 0.018 14.5 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Neurochondrin PF05536.11 EGC35073.1 - 1.2e-34 119.7 0.4 1.6e-17 63.1 0.0 3.2 2 1 0 2 2 2 2 Neurochondrin MFS_1 PF07690.16 EGC35074.1 - 6.3e-39 133.9 34.8 1.2e-32 113.2 21.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC35074.1 - 9.9e-09 34.6 30.8 1.4e-07 30.8 31.0 2.5 1 1 0 1 1 1 1 Sugar (and other) transporter OATP PF03137.20 EGC35074.1 - 0.014 13.7 21.2 0.041 12.2 0.7 3.6 2 1 1 3 3 3 0 Organic Anion Transporter Polypeptide (OATP) family SLATT_5 PF18160.1 EGC35074.1 - 5.6 6.2 10.0 2.1 7.7 0.9 3.6 3 0 0 3 3 3 0 SMODS and SLOG-associating 2TM effector domain family 5 DUF2719 PF10891.8 EGC35075.1 - 0.0055 16.6 0.9 0.015 15.1 0.9 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2719) DcrB PF08786.11 EGC35075.1 - 0.0088 16.1 0.3 0.13 12.3 0.0 2.7 3 0 0 3 3 3 1 DcrB PsbP PF01789.16 EGC35075.1 - 0.015 15.4 11.0 0.067 13.3 1.8 3.5 2 2 1 3 3 3 0 PsbP DNA_pol_B_palm PF14792.6 EGC35076.1 - 1.9e-34 118.3 0.2 6.8e-34 116.5 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta palm HHH_8 PF14716.6 EGC35076.1 - 9.8e-19 67.5 1.2 3.2e-17 62.7 0.2 2.5 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_B_thumb PF14791.6 EGC35076.1 - 1e-17 64.1 0.0 3.4e-17 62.4 0.0 2.0 2 0 0 2 2 2 1 DNA polymerase beta thumb DNA_pol_lambd_f PF10391.9 EGC35076.1 - 1.4e-17 63.2 0.0 1.4e-17 63.2 0.0 2.9 4 0 0 4 4 4 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.6 EGC35076.1 - 5.9e-08 33.2 3.7 9.9e-05 22.9 0.1 2.7 1 1 1 2 2 2 2 Helix-hairpin-helix domain NTP_transf_2 PF01909.23 EGC35076.1 - 9.3e-05 22.7 0.1 0.00029 21.0 0.1 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain HHH_3 PF12836.7 EGC35076.1 - 0.0023 18.1 0.1 0.22 11.8 0.0 2.9 2 0 0 2 2 2 1 Helix-hairpin-helix motif Cdd1 PF11731.8 EGC35076.1 - 0.0025 18.0 0.2 0.069 13.4 0.0 2.6 1 1 1 2 2 2 1 Pathogenicity locus DUF4332 PF14229.6 EGC35076.1 - 0.0048 17.1 0.0 0.012 15.8 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HHH PF00633.23 EGC35076.1 - 0.015 15.2 1.0 7 6.7 0.0 3.0 3 0 0 3 3 3 0 Helix-hairpin-helix motif TBX PF12598.8 EGC35076.1 - 0.034 15.0 1.0 0.069 14.0 1.0 1.5 1 0 0 1 1 1 0 T-box transcription factor HHH_2 PF12826.7 EGC35076.1 - 0.035 14.2 0.0 11 6.2 0.0 2.6 2 0 0 2 2 2 0 Helix-hairpin-helix motif Complex1_LYR PF05347.15 EGC35077.1 - 0.041 13.9 0.9 0.068 13.2 0.9 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC35077.1 - 0.1 13.4 0.7 0.12 13.2 0.7 1.2 1 0 0 1 1 1 0 Complex1_LYR-like CEP170_C PF15308.6 EGC35077.1 - 0.16 10.5 0.9 0.2 10.2 0.9 1.0 1 0 0 1 1 1 0 CEP170 C-terminus EXOSC1 PF10447.9 EGC35078.1 - 9.3e-14 52.0 4.6 1.7e-10 41.5 0.3 2.6 2 1 1 3 3 3 2 Exosome component EXOSC1/CSL4 ECR1_N PF14382.6 EGC35078.1 - 1.1e-12 47.6 0.1 2.2e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region CHASE5 PF17149.4 EGC35078.1 - 0.061 13.2 0.1 0.15 12.0 0.0 1.7 1 1 1 2 2 2 0 Periplasmic sensor domain found in signal transduction proteins WD40 PF00400.32 EGC35079.1 - 1.4e-06 28.9 0.6 0.014 16.3 0.0 3.3 3 0 0 3 3 3 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35079.1 - 3.1e-05 24.2 0.0 1.2 9.5 0.0 4.0 3 2 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain CNH PF00780.22 EGC35079.1 - 0.00086 19.0 0.1 1.2 8.7 0.0 2.6 1 1 0 2 2 2 2 CNH domain Ge1_WD40 PF16529.5 EGC35079.1 - 0.0011 18.0 3.0 0.043 12.8 0.1 2.9 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Lactonase PF10282.9 EGC35079.1 - 0.018 14.3 0.1 0.072 12.3 0.1 1.9 1 1 0 1 1 1 0 Lactonase, 7-bladed beta-propeller YmzC PF14157.6 EGC35079.1 - 0.083 13.0 0.0 7.1 6.8 0.0 2.7 2 0 0 2 2 2 0 YmzC-like protein RRM_1 PF00076.22 EGC35081.1 - 7.9e-20 70.5 0.2 1.1e-19 70.0 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC35081.1 - 0.00013 22.0 0.1 0.00026 21.0 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif RRM_5 PF13893.6 EGC35081.1 - 0.00027 20.5 0.0 0.00036 20.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Macoilin PF09726.9 EGC35082.1 - 1.8 7.0 9.0 2.5 6.5 9.0 1.1 1 0 0 1 1 1 0 Macoilin family Bee_toxin PF17454.2 EGC35082.1 - 9.7 6.3 8.0 0.41 10.7 1.4 2.1 2 0 0 2 2 2 0 Honey bee toxin MutL_C PF08676.11 EGC35083.1 - 1.1e-28 99.8 0.0 3.4e-28 98.2 0.0 1.9 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.19 EGC35083.1 - 1.2e-23 83.1 0.0 2.3e-22 78.9 0.0 2.7 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.6 EGC35083.1 - 3.6e-12 46.3 0.0 3.6e-12 46.3 0.0 2.7 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.26 EGC35083.1 - 9.6e-06 26.1 0.0 3.4e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase E1-E2_ATPase PF00122.20 EGC35084.1 - 3.3e-52 176.6 1.0 7.4e-52 175.5 1.0 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGC35084.1 - 6.1e-45 154.1 0.1 9.4e-45 153.5 0.1 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.26 EGC35084.1 - 3.8e-26 91.3 3.1 3.5e-14 53.0 0.2 2.9 3 0 0 3 3 3 2 Heavy-metal-associated domain Hydrolase_3 PF08282.12 EGC35084.1 - 2.2e-05 24.3 3.0 0.001 18.8 1.0 2.7 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC35084.1 - 0.083 13.3 0.0 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD2 PF18782.1 EGC35084.1 - 0.085 13.0 0.0 0.4 10.8 0.0 2.0 2 1 1 3 3 3 0 Novel AID APOBEC clade 2 Toxin-deaminase PF14424.6 EGC35084.1 - 1.6 8.8 7.0 2.5 8.2 0.1 2.8 2 1 1 3 3 3 0 The BURPS668_1122 family of deaminases RCC1 PF00415.18 EGC35085.1 - 1.1e-70 234.1 5.7 3.6e-11 43.5 0.2 7.1 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC35085.1 - 5.3e-24 83.4 46.0 2.7e-11 43.0 0.7 9.1 9 2 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.6 EGC35085.1 - 0.12 12.8 1.1 1.1 9.7 0.0 2.9 3 0 0 3 3 3 0 Kelch motif Peptidase_C25_C PF03785.14 EGC35085.1 - 0.14 12.1 0.0 6.6 6.7 0.0 2.8 2 1 1 3 3 3 0 Peptidase family C25, C terminal ig-like domain Adaptin_N PF01602.20 EGC35086.1 - 1e-86 291.6 12.7 1.6e-86 291.0 12.7 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.6 EGC35086.1 - 9.4e-52 174.3 0.1 9.4e-52 174.3 0.1 2.6 3 0 0 3 3 3 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.12 EGC35086.1 - 2.1e-46 157.3 0.9 5.7e-46 155.9 0.9 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.6 EGC35086.1 - 2.6e-05 24.5 0.0 0.017 15.5 0.0 3.8 2 2 2 4 4 4 1 HEAT repeats HEAT PF02985.22 EGC35086.1 - 0.0001 22.2 0.8 12 6.5 0.0 5.4 5 0 0 5 5 5 1 HEAT repeat Cnd1 PF12717.7 EGC35086.1 - 0.00017 21.7 12.7 0.00038 20.5 0.0 3.8 3 1 0 5 5 5 2 non-SMC mitotic condensation complex subunit 1 Coatomer_g_Cpla PF16381.5 EGC35086.1 - 0.011 15.9 0.0 0.063 13.4 0.0 2.4 2 0 0 2 2 2 0 Coatomer subunit gamma-1 C-terminal appendage platform RhoGEF PF00621.20 EGC35087.1 - 5.7e-54 183.1 4.9 5.7e-54 183.1 4.9 2.0 2 0 0 2 2 2 1 RhoGEF domain IQ PF00612.27 EGC35087.1 - 4.4e-05 22.9 0.7 0.00011 21.7 0.7 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 EGC35087.1 - 0.0033 17.9 7.8 0.065 13.8 1.8 3.6 2 1 0 2 2 2 1 PH domain PH_2 PF08458.10 EGC35087.1 - 0.036 14.4 0.0 0.49 10.8 0.0 2.5 2 0 0 2 2 2 0 Plant pleckstrin homology-like region Zip PF02535.22 EGC35087.1 - 3.9 6.6 4.5 4 6.6 1.1 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter Hydrolase_6 PF13344.6 EGC35089.1 - 2.7e-25 88.4 0.0 7.6e-25 87.0 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGC35089.1 - 8.3e-17 61.0 0.0 5.3e-16 58.4 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.26 EGC35089.1 - 3.6e-11 43.7 0.0 4.3e-11 43.5 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGC35089.1 - 1.9e-08 34.6 3.9 0.00017 21.7 0.0 2.7 1 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase PGP_phosphatase PF09419.10 EGC35089.1 - 0.02 14.5 1.6 7.1 6.2 0.1 2.9 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Terpene_synth_C PF03936.16 EGC35090.1 - 0.01 15.2 0.1 0.019 14.3 0.1 1.4 1 1 0 1 1 1 0 Terpene synthase family, metal binding domain Swi3 PF07962.12 EGC35091.1 - 2.4e-13 49.9 0.0 5.3e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 FAA_hydrolase_N PF09298.11 EGC35091.1 - 0.019 15.1 0.0 0.072 13.3 0.0 1.9 1 0 0 1 1 1 0 Fumarylacetoacetase N-terminal Nucleopor_Nup85 PF07575.13 EGC35092.1 - 2.2e-63 214.8 24.6 2.2e-63 214.8 24.6 2.0 2 0 0 2 2 2 2 Nup85 Nucleoporin zf-C2H2_3rep PF18868.1 EGC35093.1 - 1.1e-05 26.0 8.4 0.0018 19.0 2.8 2.4 2 0 0 2 2 2 2 Zinc finger C2H2-type, 3 repeats zf-C2H2_jaz PF12171.8 EGC35093.1 - 0.055 13.8 9.8 0.68 10.3 0.3 3.7 2 1 1 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGC35093.1 - 0.32 11.4 7.2 2.9 8.4 0.5 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type FNIP PF05725.12 EGC35094.1 - 2e-90 296.7 29.1 2e-15 56.7 1.1 7.0 1 1 5 8 8 8 8 FNIP Repeat FNIP PF05725.12 EGC35096.1 - 7.9e-25 86.8 63.2 9.8e-06 25.6 0.5 12.6 10 3 4 14 14 14 9 FNIP Repeat WD40 PF00400.32 EGC35097.1 - 6.3e-11 42.7 1.8 2.4 9.2 0.1 7.5 7 1 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35097.1 - 1.5e-05 25.2 0.8 9.8 6.6 0.0 4.6 5 1 1 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF1652 PF07865.11 EGC35097.1 - 0.2 11.5 0.0 3.2 7.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) WD40_like PF17005.5 EGC35097.1 - 0.35 10.2 5.4 0.31 10.3 1.6 2.7 2 1 1 3 3 3 0 WD40-like domain PaaX_C PF08223.11 EGC35098.1 - 0.11 12.7 0.2 0.77 10.1 0.0 2.2 2 0 0 2 2 2 0 PaaX-like protein C-terminal domain Zip PF02535.22 EGC35098.1 - 0.76 8.9 7.9 2.5 7.2 8.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter Presenilin PF01080.17 EGC35098.1 - 5.4 5.7 5.0 7.3 5.2 5.0 1.2 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EGC35099.1 - 8.5e-27 93.6 4.8 5.5e-07 30.1 0.1 5.6 1 1 6 7 7 7 7 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC35099.1 - 1.9e-18 66.6 3.7 0.0023 18.5 0.0 7.3 4 2 4 8 8 8 7 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC35099.1 - 8.8e-15 53.3 2.2 7.9 7.4 0.0 10.3 10 1 1 11 11 11 3 Ankyrin repeat Ank_5 PF13857.6 EGC35099.1 - 9.3e-15 54.5 2.1 1.2 9.5 0.0 9.1 4 3 6 10 10 10 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC35099.1 - 2.4e-05 24.6 4.4 5.5 7.6 0.0 7.1 5 3 0 5 5 5 1 Ankyrin repeat DUF249 PF03158.13 EGC35099.1 - 0.00014 21.6 3.6 0.36 10.5 0.1 4.2 2 2 0 2 2 2 2 Multigene family 530 protein 2OG-FeII_Oxy_3 PF13640.6 EGC35100.1 - 0.1 13.5 0.0 0.22 12.5 0.0 1.5 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Dicty_spore_N PF04562.12 EGC35101.1 - 9e-27 94.0 25.4 9e-27 94.0 25.4 4.1 3 1 0 3 3 3 2 Dictyostelium spore coat protein, N terminus Glyco_hydro_130 PF04041.13 EGC35102.1 - 7.1e-19 67.9 0.0 1.2e-18 67.1 0.0 1.3 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase DUF1935 PF09149.10 EGC35102.1 - 0.1 13.0 0.1 0.24 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) FSAP_sig_propep PF03032.15 EGC35102.1 - 0.33 11.0 1.0 0.66 10.1 1.0 1.4 1 0 0 1 1 1 0 Frog skin active peptide family signal and propeptide UbiA PF01040.18 EGC35103.1 - 1.4e-21 76.9 3.9 1.9e-21 76.5 3.9 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_Gp23 PF10669.9 EGC35104.1 - 0.0022 18.3 0.1 0.0048 17.2 0.1 1.6 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) UPF0029 PF01205.19 EGC35105.1 - 8.2e-30 103.2 1.0 1.5e-29 102.4 0.0 1.8 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.22 EGC35105.1 - 3.5e-23 82.1 3.1 3.5e-23 82.1 3.1 2.5 2 1 0 2 2 2 1 RWD domain DUF2722 PF10846.8 EGC35105.1 - 0.0038 16.2 7.5 0.0054 15.7 7.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) DUF1115 PF06544.12 EGC35105.1 - 0.014 15.5 1.2 0.025 14.7 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1115) KOG2701 PF09762.9 EGC35105.1 - 0.023 14.9 3.5 0.037 14.3 3.5 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) SR-25 PF10500.9 EGC35105.1 - 0.068 12.8 6.1 0.11 12.0 6.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4834 PF16118.5 EGC35105.1 - 0.26 12.3 4.8 0.55 11.2 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Presenilin PF01080.17 EGC35105.1 - 0.91 8.2 2.9 1.2 7.8 2.9 1.1 1 0 0 1 1 1 0 Presenilin ABC2_membrane_3 PF12698.7 EGC35105.1 - 1.5 7.9 5.5 2.1 7.4 5.5 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Hydin_ADK PF17213.3 EGC35106.1 - 3.6 7.8 8.7 3.2 8.0 7.5 1.4 1 1 0 1 1 1 0 Hydin Adenylate kinase-like domain ABC_membrane PF00664.23 EGC35107.1 - 1.8e-68 231.2 32.0 8.3e-38 130.6 16.2 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC35107.1 - 2.6e-48 164.0 1.5 2.5e-28 99.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.19 EGC35107.1 - 3.9e-07 29.7 5.6 0.087 12.3 0.1 4.4 3 1 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC35107.1 - 2.1e-05 24.2 1.8 0.094 12.5 0.3 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain TrwB_AAD_bind PF10412.9 EGC35107.1 - 0.0027 16.7 0.3 0.14 11.0 0.0 2.3 2 0 0 2 2 2 1 Type IV secretion-system coupling protein DNA-binding domain MMR_HSR1 PF01926.23 EGC35107.1 - 0.0036 17.4 0.4 4.4 7.4 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_21 PF13304.6 EGC35107.1 - 0.0082 16.0 1.1 0.81 9.4 0.0 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system T2SSE PF00437.20 EGC35107.1 - 0.0092 15.1 0.0 2.1 7.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGC35107.1 - 0.011 15.2 0.3 4.6 6.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family RsgA_GTPase PF03193.16 EGC35107.1 - 0.011 15.6 0.5 0.14 12.0 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EGC35107.1 - 0.035 13.6 0.2 4 6.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGC35107.1 - 0.055 13.8 0.0 3 8.2 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.17 EGC35107.1 - 0.056 13.5 0.2 0.056 13.5 0.2 2.7 3 0 0 3 3 2 0 Helicase HerA, central domain Zeta_toxin PF06414.12 EGC35107.1 - 0.067 12.5 0.3 1.2 8.3 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_22 PF13401.6 EGC35107.1 - 0.089 13.1 3.0 4.1 7.7 0.2 3.1 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC35107.1 - 0.16 11.6 0.3 25 4.5 0.0 2.7 2 1 0 2 2 2 0 AAA domain cobW PF02492.19 EGC35107.1 - 0.34 10.5 2.0 0.49 10.0 0.2 2.0 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain Pex24p PF06398.11 EGC35107.1 - 0.51 9.3 4.0 0.17 10.8 0.9 1.8 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin UbiA PF01040.18 EGC35108.1 - 1.3e-28 100.0 4.4 1.7e-28 99.6 4.4 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Spt20 PF12090.8 EGC35108.1 - 0.049 13.2 0.0 0.069 12.8 0.0 1.2 1 0 0 1 1 1 0 Spt20 family tRNA-synt_1c PF00749.21 EGC35109.1 - 4.6e-101 337.8 0.3 4.2e-100 334.7 0.1 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.18 EGC35109.1 - 1.2e-40 139.2 0.9 2.9e-40 138.0 0.5 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C PF00043.25 EGC35109.1 - 2.4e-06 27.7 0.0 5.3e-06 26.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC35109.1 - 5.3e-06 26.5 0.2 2.4e-05 24.5 0.1 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain Glyco_hydro_28 PF00295.17 EGC35109.1 - 0.037 13.1 0.0 0.064 12.3 0.0 1.3 1 0 0 1 1 1 0 Glycosyl hydrolases family 28 Erf4 PF10256.9 EGC35109.1 - 0.073 13.2 2.6 0.28 11.3 0.1 2.7 3 0 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family ABC2_membrane PF01061.24 EGC35111.1 - 3e-74 249.0 44.1 1.9e-38 132.0 12.9 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC35111.1 - 4.9e-43 146.9 0.1 3e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_18 PF13238.6 EGC35111.1 - 4.6e-09 36.9 0.1 0.0034 17.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGC35111.1 - 2.1e-07 30.5 0.3 0.0024 17.6 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC35111.1 - 2.4e-07 31.1 0.2 0.018 15.3 0.1 2.9 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.6 EGC35111.1 - 2.5e-07 31.2 0.0 0.026 14.9 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGC35111.1 - 4e-07 30.1 0.2 0.00041 20.3 0.0 2.9 3 0 0 3 3 2 1 RsgA GTPase AAA_33 PF13671.6 EGC35111.1 - 9.1e-06 25.9 0.0 0.087 13.0 0.0 2.4 2 0 0 2 2 2 2 AAA domain PDR_assoc PF08370.11 EGC35111.1 - 3.7e-05 23.4 2.5 0.075 12.8 0.4 3.0 2 0 0 2 2 2 2 Plant PDR ABC transporter associated Rad17 PF03215.15 EGC35111.1 - 6.7e-05 22.9 0.0 0.16 11.8 0.0 3.1 3 0 0 3 3 3 1 Rad17 P-loop domain PDR_CDR PF06422.12 EGC35111.1 - 0.00012 21.9 3.1 0.3 11.0 0.7 3.0 2 0 0 2 2 2 2 CDR ABC transporter SMC_N PF02463.19 EGC35111.1 - 0.00031 20.3 0.2 4.2 6.7 0.0 3.6 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGC35111.1 - 0.00031 20.7 0.5 1.5 8.5 0.0 3.2 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system NACHT PF05729.12 EGC35111.1 - 0.0004 20.3 0.2 0.098 12.6 0.0 2.5 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.6 EGC35111.1 - 0.00045 20.0 0.5 0.54 10.0 0.0 2.9 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.23 EGC35111.1 - 0.00069 19.7 0.0 0.27 11.3 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.22 EGC35111.1 - 0.00073 19.9 0.0 1.6 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase AAA PF00004.29 EGC35111.1 - 0.001 19.5 0.1 2.2 8.7 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGC35111.1 - 0.0014 18.4 0.1 1.9 8.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain Ploopntkinase3 PF18751.1 EGC35111.1 - 0.0015 18.5 0.1 0.44 10.4 0.0 2.3 2 0 0 2 2 2 1 P-loop Nucleotide Kinase3 AAA_14 PF13173.6 EGC35111.1 - 0.0047 17.0 0.0 2.8 8.0 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC35111.1 - 0.0055 16.3 0.0 4.3 6.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.6 EGC35111.1 - 0.0077 16.7 0.1 3.9 7.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.6 EGC35111.1 - 0.0082 16.4 0.0 1.3 9.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGC35111.1 - 0.0087 15.6 0.1 1.7 8.1 0.0 3.1 3 0 0 3 3 3 1 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGC35111.1 - 0.026 13.8 0.0 4.4 6.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin Cytidylate_kin PF02224.18 EGC35111.1 - 0.034 13.9 0.1 0.37 10.5 0.1 2.1 2 0 0 2 2 2 0 Cytidylate kinase TsaE PF02367.17 EGC35111.1 - 0.049 13.6 0.4 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NB-ARC PF00931.22 EGC35111.1 - 0.055 12.6 1.1 3.5 6.7 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain cobW PF02492.19 EGC35111.1 - 0.059 13.0 3.0 2.1 7.9 0.1 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain DUF815 PF05673.13 EGC35111.1 - 0.069 12.3 0.1 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGC35111.1 - 0.072 12.8 0.0 20 4.8 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EGC35111.1 - 0.072 13.6 0.7 0.47 10.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_5 PF07728.14 EGC35111.1 - 0.3 11.1 4.5 13 5.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.21 EGC35111.1 - 0.73 9.2 1.9 3.2 7.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Glyco_hydro_38N PF01074.22 EGC35112.1 - 4.9e-82 275.6 0.8 7.2e-82 275.0 0.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.13 EGC35112.1 - 4.7e-55 187.0 0.0 8.3e-55 186.2 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.11 EGC35112.1 - 1.6e-24 85.8 0.0 2.2e-23 82.2 0.0 2.4 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro38C2 PF17677.1 EGC35112.1 - 6.4e-12 45.4 0.0 1.6e-11 44.2 0.0 1.7 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal beta sandwich domain Glyco_hydro_57 PF03065.15 EGC35112.1 - 0.0025 17.1 0.0 0.0049 16.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Cation_efflux PF01545.21 EGC35113.1 - 0.011 15.4 3.6 0.015 15.1 3.6 1.1 1 0 0 1 1 1 0 Cation efflux family Erf4 PF10256.9 EGC35113.1 - 0.013 15.6 4.2 0.18 11.9 2.0 2.9 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family RDD PF06271.12 EGC35113.1 - 0.027 14.7 0.8 0.033 14.4 0.8 1.1 1 0 0 1 1 1 0 RDD family Amnionless PF14828.6 EGC35113.1 - 0.091 11.6 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Amnionless DENN PF02141.21 EGC35115.1 - 5.2e-21 75.4 12.4 1.7e-19 70.5 3.8 3.4 2 1 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.18 EGC35115.1 - 3.8e-11 43.6 0.4 2e-10 41.2 0.4 2.2 2 0 0 2 2 2 1 uDENN domain Avl9 PF09794.9 EGC35115.1 - 2.9e-06 26.2 0.5 2.9e-06 26.2 0.5 1.8 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.10 EGC35115.1 - 0.00021 21.2 1.0 0.00073 19.5 1.0 2.0 1 0 0 1 1 1 1 Stabilization of polarity axis dDENN PF03455.19 EGC35115.1 - 0.0065 16.4 2.5 0.018 15.0 2.5 1.8 1 0 0 1 1 1 1 dDENN domain Telomere_res PF16684.5 EGC35116.1 - 0.0025 17.3 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 Telomere resolvase Acetyltransf_4 PF13420.7 EGC35116.1 - 0.0062 16.7 1.1 0.013 15.7 0.5 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain DUF5488 PF17590.2 EGC35116.1 - 0.23 11.2 2.8 8 6.3 0.0 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5488) WD40 PF00400.32 EGC35117.1 - 9.2e-17 61.1 18.4 0.0013 19.6 0.2 7.0 6 0 0 6 6 6 5 WD domain, G-beta repeat Zn_ribbon_17 PF17120.5 EGC35117.1 - 6.2e-10 38.5 9.9 6.2e-10 38.5 9.9 2.4 1 1 1 2 2 2 2 Zinc-ribbon, C4HC2 type ANAPC4_WD40 PF12894.7 EGC35117.1 - 1.2e-07 32.0 0.9 0.058 13.7 0.1 3.8 2 1 2 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain CDC45 PF02724.14 EGC35117.1 - 0.00046 18.6 8.2 0.00046 18.6 8.2 2.3 2 0 0 2 2 2 1 CDC45-like protein BBS2_Mid PF14783.6 EGC35117.1 - 0.0077 16.3 0.0 0.1 12.6 0.0 2.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region zinc_ribbon_2 PF13240.6 EGC35117.1 - 0.01 15.5 3.1 0.01 15.5 3.1 3.0 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.7 EGC35117.1 - 0.058 13.4 8.8 0.17 11.9 8.8 1.9 1 0 0 1 1 1 0 Double zinc ribbon C1_2 PF03107.16 EGC35117.1 - 4.6 7.6 10.5 14 6.1 3.0 2.9 1 1 1 2 2 2 0 C1 domain Methyltransf_2 PF00891.18 EGC35118.1 - 1.4e-41 142.1 0.0 1.9e-41 141.7 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Sigma70_r4_2 PF08281.12 EGC35118.1 - 0.1 12.3 0.1 0.28 10.9 0.1 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 HTH_23 PF13384.6 EGC35118.1 - 0.17 11.7 0.0 0.37 10.7 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain MAD PF05557.13 EGC35119.1 - 2.7e-52 178.1 94.8 1.1e-37 129.9 2.8 3.8 1 1 2 3 3 3 2 Mitotic checkpoint protein PKcGMP_CC PF16808.5 EGC35119.1 - 0.012 15.5 0.8 0.012 15.5 0.8 7.6 8 0 0 8 8 8 0 Coiled-coil N-terminus of cGMP-dependent protein kinase Methyltransf_11 PF08241.12 EGC35120.1 - 3.7e-15 56.3 0.0 9.9e-15 55.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC35120.1 - 1.4e-14 54.2 0.0 3.1e-14 53.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC35120.1 - 1.5e-12 47.6 0.0 4.1e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC35120.1 - 3.8e-12 46.8 0.0 8.7e-12 45.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC35120.1 - 2.3e-11 44.3 0.0 2.3e-11 44.3 0.0 3.5 3 1 1 4 4 4 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC35120.1 - 0.0006 19.2 0.0 0.001 18.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC35120.1 - 0.003 17.1 0.1 0.011 15.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DUF5501 PF17605.2 EGC35121.1 - 0.049 14.1 1.8 0.13 12.7 1.8 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5501) Exo_endo_phos_2 PF14529.6 EGC35121.1 - 0.068 13.0 0.1 0.21 11.4 0.1 2.0 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ELFV_dehydrog_N PF02812.18 EGC35122.1 - 2.6e-55 185.8 0.0 4.7e-55 185.0 0.0 1.4 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain ELFV_dehydrog PF00208.21 EGC35122.1 - 5.3e-53 180.2 0.0 5e-51 173.8 0.0 2.2 1 1 1 2 2 2 2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.19 EGC35122.1 - 0.023 14.0 0.1 0.042 13.2 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Bac_GDH PF05088.12 EGC35122.1 - 0.03 11.8 0.0 0.65 7.4 0.0 2.0 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase AdoHcyase_NAD PF00670.21 EGC35122.1 - 0.07 13.2 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain NAD_binding_7 PF13241.6 EGC35122.1 - 0.099 13.1 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Putative NAD(P)-binding DUF3430 PF11912.8 EGC35123.1 - 7.2e-19 68.7 23.0 8.6e-19 68.4 23.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC35123.1 - 0.043 14.0 6.5 0.11 12.7 0.9 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3586) Metallothio_Euk PF12749.7 EGC35124.1 - 0.064 13.4 2.7 0.14 12.3 2.7 1.5 1 0 0 1 1 1 0 Eukaryotic metallothionein Dynamin_N PF00350.23 EGC35126.1 - 4.6e-39 134.2 0.1 4.6e-39 134.2 0.1 3.3 3 0 0 3 3 3 1 Dynamin family MMR_HSR1 PF01926.23 EGC35126.1 - 4.6e-05 23.5 0.2 0.00037 20.5 0.2 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase NPV_P10 PF05531.12 EGC35126.1 - 0.19 12.2 4.6 0.23 11.9 1.6 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein ARGLU PF15346.6 EGC35126.1 - 1 9.3 19.1 0.087 12.7 9.9 3.0 2 0 0 2 2 2 0 Arginine and glutamate-rich 1 FlaC_arch PF05377.11 EGC35126.1 - 2.2 8.7 13.7 0.41 11.1 0.9 4.3 4 0 0 4 4 4 0 Flagella accessory protein C (FlaC) Exonuc_VII_L PF02601.15 EGC35126.1 - 3.3 7.2 15.0 7.4 6.0 0.5 2.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit EGF_2 PF07974.13 EGC35127.1 - 0.019 15.3 39.8 0.069 13.5 14.3 2.9 2 0 0 2 2 2 0 EGF-like domain FlaG PF03646.15 EGC35127.1 - 0.061 13.5 0.8 0.12 12.5 0.8 1.4 1 0 0 1 1 1 0 FlaG protein Laminin_EGF PF00053.24 EGC35127.1 - 1.4 9.1 36.7 0.21 11.8 10.5 3.3 3 1 0 3 3 3 0 Laminin EGF domain 7tm_3 PF00003.22 EGC35128.1 - 3.4e-45 154.6 25.1 4.6e-45 154.2 25.1 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC35128.1 - 1.1e-15 57.4 0.8 1.6e-15 56.9 0.8 1.2 1 0 0 1 1 1 1 ABC transporter substrate-binding protein PnrA-like DUF3112 PF11309.8 EGC35128.1 - 0.014 14.9 4.5 1.2 8.5 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3112) DUF4711 PF15829.5 EGC35129.1 - 0.041 13.8 0.2 0.079 12.9 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4711) ALMT PF11744.8 EGC35129.1 - 0.14 10.9 5.3 0.22 10.3 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter MCU PF04678.13 EGC35129.1 - 0.18 11.9 1.7 0.84 9.7 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial calcium uniporter Zip PF02535.22 EGC35129.1 - 3.1 6.9 5.3 1.6 7.9 0.2 2.4 2 0 0 2 2 2 0 ZIP Zinc transporter Casc1 PF12366.8 EGC35130.1 - 0.09 12.3 0.0 0.11 12.0 0.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 MotB_plug PF13677.6 EGC35130.1 - 0.16 11.6 1.6 0.32 10.6 1.6 1.5 1 0 0 1 1 1 0 Membrane MotB of proton-channel complex MotA/MotB Tmemb_cc2 PF10267.9 EGC35131.1 - 0.022 13.9 0.3 0.034 13.3 0.3 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Thioredoxin PF00085.20 EGC35132.1 - 1.6e-28 98.7 1.3 4e-21 74.9 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin OST3_OST6 PF04756.13 EGC35132.1 - 8.8e-08 31.8 0.1 1.6e-05 24.5 0.1 2.2 1 1 1 2 2 2 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGC35132.1 - 3.2e-07 30.8 0.8 0.00011 22.6 0.2 2.7 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.6 EGC35132.1 - 0.0017 18.3 4.0 0.19 11.6 0.4 3.3 3 1 0 3 3 3 2 Thioredoxin-like domain Glutaredoxin PF00462.24 EGC35132.1 - 0.0018 18.4 0.5 0.49 10.6 0.2 2.6 2 0 0 2 2 2 2 Glutaredoxin Calsequestrin PF01216.17 EGC35132.1 - 0.006 15.7 1.3 0.29 10.1 0.1 2.1 1 1 0 2 2 2 2 Calsequestrin DUF836 PF05768.14 EGC35132.1 - 0.066 13.6 1.3 4.8 7.7 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) ECH_2 PF16113.5 EGC35133.1 - 6.1e-96 321.8 0.0 6.9e-96 321.6 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGC35133.1 - 6.4e-20 71.5 0.0 1.4e-19 70.4 0.0 1.6 1 1 1 2 2 2 1 Enoyl-CoA hydratase/isomerase DEAD PF00270.29 EGC35134.1 - 1.6e-20 73.6 0.0 4.9e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC35134.1 - 6.7e-16 58.6 1.0 2.5e-15 56.8 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF1998 PF09369.10 EGC35134.1 - 0.00045 20.9 0.1 0.0015 19.2 0.1 2.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Flp_N PF03930.14 EGC35134.1 - 0.033 14.2 2.0 0.58 10.2 0.3 3.6 3 0 0 3 3 3 0 Recombinase Flp protein N-terminus Pkinase PF00069.25 EGC35135.1 - 3.4e-15 56.1 0.1 7.2e-15 55.1 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35135.1 - 2.8e-10 39.9 0.0 5.2e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.22 EGC35135.1 - 0.00028 20.9 0.0 3.5 8.1 0.0 3.7 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.6 EGC35135.1 - 0.0011 18.3 0.0 0.0064 15.8 0.0 2.0 2 0 0 2 2 2 1 Kinase-like Adaptin_N PF01602.20 EGC35135.1 - 0.0037 15.9 0.1 0.021 13.4 0.0 1.9 1 1 1 2 2 2 1 Adaptin N terminal region Cnd1 PF12717.7 EGC35135.1 - 0.0075 16.3 0.4 0.037 14.1 0.0 2.3 2 2 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGC35135.1 - 0.038 14.4 0.0 0.13 12.6 0.0 1.9 2 0 0 2 2 2 0 HEAT repeats HEAT_EZ PF13513.6 EGC35135.1 - 0.044 14.3 0.0 2.4 8.7 0.0 2.9 2 1 1 3 3 3 0 HEAT-like repeat Pkinase PF00069.25 EGC35136.1 - 8e-70 235.2 0.0 9.2e-70 235.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35136.1 - 1.2e-30 106.7 0.0 1.6e-30 106.3 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC35136.1 - 0.00014 21.3 0.0 0.0087 15.4 0.0 2.2 1 1 1 2 2 2 2 Kinase-like MutS_V PF00488.21 EGC35137.1 - 6.4e-76 254.6 0.6 1.3e-75 253.6 0.6 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGC35137.1 - 1.2e-37 130.1 2.5 2.4e-37 129.0 1.2 2.2 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGC35137.1 - 7e-34 116.5 0.0 1.7e-33 115.2 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGC35137.1 - 3.7e-16 59.6 1.4 4.1e-15 56.3 0.0 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.18 EGC35137.1 - 5.7e-10 39.4 1.5 5.7e-10 39.4 1.5 2.3 2 0 0 2 2 2 1 MutS family domain IV PBP1_TM PF14812.6 EGC35137.1 - 0.0086 16.4 7.4 0.02 15.2 7.4 1.6 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal Pil1 PF13805.6 EGC35137.1 - 0.038 13.5 0.1 0.089 12.3 0.1 1.6 1 0 0 1 1 1 0 Eisosome component PIL1 MtrG PF04210.13 EGC35137.1 - 1 9.3 2.9 10 6.0 0.2 2.7 2 0 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase, subunit G Sec8_exocyst PF04048.14 EGC35137.1 - 2.1 8.2 7.1 11 5.9 0.1 3.9 2 1 2 4 4 4 0 Sec8 exocyst complex component specific domain NOA36 PF06524.12 EGC35137.1 - 4 6.7 7.9 9.2 5.5 7.9 1.5 1 0 0 1 1 1 0 NOA36 protein DUF4611 PF15387.6 EGC35137.1 - 8.7 6.6 10.0 36 4.6 10.0 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DAO PF01266.24 EGC35138.1 - 1.9e-55 188.8 0.0 2.5e-55 188.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGC35138.1 - 0.00021 20.6 0.0 0.00034 19.9 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Mqo PF06039.15 EGC35138.1 - 0.0003 19.5 0.0 0.046 12.3 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_2 PF07992.14 EGC35138.1 - 0.00059 19.2 0.1 0.029 13.6 0.1 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC35138.1 - 0.0013 18.9 0.0 0.003 17.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.12 EGC35138.1 - 0.21 10.6 0.0 0.36 9.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein Pkinase PF00069.25 EGC35140.1 - 1.7e-57 194.8 0.0 2.5e-57 194.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35140.1 - 2.7e-57 194.0 0.0 3.8e-57 193.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC35140.1 - 0.00046 19.6 0.0 0.00071 19.0 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Muted PF14942.6 EGC35141.1 - 2.5e-31 109.0 15.7 3.1e-31 108.7 15.7 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein EF-hand_like PF09279.11 EGC35141.1 - 1.9 9.0 9.1 1.4 9.5 3.9 2.6 2 1 1 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like DUF745 PF05335.13 EGC35141.1 - 4.1 7.1 8.3 5.8 6.6 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) ADH_zinc_N_2 PF13602.6 EGC35142.1 - 1.8e-05 25.8 0.0 1.9e-05 25.7 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase KinB_sensor PF16767.5 EGC35142.1 - 0.031 14.7 0.0 0.036 14.5 0.0 1.0 1 0 0 1 1 1 0 Sensor domain of alginate biosynthesis sensor protein KinB DUF929 PF06053.11 EGC35142.1 - 0.07 12.4 0.0 0.081 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ADH_N PF08240.12 EGC35143.1 - 1.7e-09 37.5 0.0 2.3e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC35143.1 - 3.5e-09 36.7 0.0 5.4e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGC35143.1 - 0.056 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF3567 PF12091.8 EGC35144.1 - 0.024 14.7 0.6 0.13 12.4 0.6 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3567) PH_12 PF16457.5 EGC35144.1 - 0.031 14.8 0.2 0.13 12.8 0.2 2.1 1 0 0 1 1 1 0 Pleckstrin homology domain Methyltransf_23 PF13489.6 EGC35145.1 - 2.8e-06 27.3 0.0 2.8e-06 27.3 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC35145.1 - 3.5e-06 27.7 0.1 3.5e-06 27.7 0.1 3.1 2 2 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC35145.1 - 3.3e-05 23.7 0.1 3.3e-05 23.7 0.1 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC35145.1 - 0.00018 22.2 0.0 0.00056 20.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGC35145.1 - 0.0013 18.2 0.0 0.0013 18.2 0.0 2.4 2 1 0 2 2 2 1 Putative methyltransferase Methyltransf_11 PF08241.12 EGC35145.1 - 0.0031 18.1 0.1 0.0086 16.7 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.7 EGC35145.1 - 0.035 14.0 0.0 0.035 14.0 0.0 2.4 2 1 1 3 3 3 0 Methyltransferase domain Methyltransf_32 PF13679.6 EGC35145.1 - 0.037 14.0 0.4 0.037 14.0 0.4 2.2 1 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.14 EGC35145.1 - 0.044 13.3 0.0 0.044 13.3 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase small domain Tim54 PF11711.8 EGC35145.1 - 1.2 7.9 13.1 2.3 6.9 5.6 2.1 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Methyltransf_9 PF08003.11 EGC35145.1 - 1.4 7.8 5.8 1.8 7.4 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) Gti1_Pac2 PF09729.9 EGC35145.1 - 2.6 8.1 20.8 4.8 7.2 0.6 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family POP1 PF06978.11 EGC35145.1 - 6.1 6.8 13.7 15 5.5 8.0 2.1 2 0 0 2 2 2 0 Ribonucleases P/MRP protein subunit POP1 Prefoldin_2 PF01920.20 EGC35146.1 - 5.7e-21 74.5 3.5 6.4e-21 74.3 3.5 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF677 PF05055.12 EGC35146.1 - 0.0027 16.7 1.4 1.1 8.1 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF677) GPHR_N PF12537.8 EGC35146.1 - 0.14 12.3 0.7 2 8.5 0.2 2.1 2 0 0 2 2 2 0 The Golgi pH Regulator (GPHR) Family N-terminal DUF5339 PF17274.2 EGC35146.1 - 0.16 12.8 1.8 2.8 8.9 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5339) IFP_35_N PF07334.13 EGC35146.1 - 0.19 11.8 5.8 0.47 10.6 2.1 2.2 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FNIP PF05725.12 EGC35147.1 - 9e-117 381.1 36.4 1.5e-16 60.2 0.1 9.3 7 2 2 9 9 9 9 FNIP Repeat LRR_5 PF13306.6 EGC35147.1 - 0.00021 21.3 2.0 0.69 9.9 0.5 3.4 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC35147.1 - 0.046 13.9 6.9 18 5.7 0.1 6.6 5 2 2 7 7 7 0 Protein of unknown function (DUF1769) Pox_D5 PF03288.16 EGC35147.1 - 3.2 8.3 9.1 37 4.9 0.9 4.4 2 2 2 4 4 4 0 Poxvirus D5 protein-like Amino_oxidase PF01593.24 EGC35148.1 - 2e-19 70.2 0.0 1.1e-16 61.2 0.0 2.3 2 1 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC35148.1 - 2.7e-17 62.7 0.0 9.6e-17 61.0 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGC35148.1 - 1.5e-11 44.5 1.1 3.9e-07 30.0 0.6 2.7 2 1 0 2 2 2 2 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGC35148.1 - 7.1e-07 28.7 0.0 0.0002 20.7 0.0 2.2 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGC35148.1 - 1.9e-05 23.9 0.2 2.8e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.14 EGC35148.1 - 0.00017 20.4 0.5 0.00052 18.8 0.4 1.8 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.27 EGC35148.1 - 0.00019 21.9 0.4 0.0015 19.1 0.2 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC35148.1 - 0.0034 16.7 0.1 0.066 12.5 0.1 2.4 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC35148.1 - 0.0095 15.2 0.1 0.016 14.5 0.1 1.2 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGC35148.1 - 0.03 13.7 0.1 0.053 12.9 0.1 1.4 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.19 EGC35148.1 - 0.036 13.3 0.4 0.058 12.6 0.4 1.3 1 0 0 1 1 1 0 FAD binding domain ApbA PF02558.16 EGC35148.1 - 0.077 12.6 0.1 0.48 10.0 0.0 2.0 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA 3HCDH_N PF02737.18 EGC35148.1 - 0.15 12.0 0.2 0.25 11.2 0.2 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain GIDA PF01134.22 EGC35148.1 - 0.15 11.1 0.3 0.35 9.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A TPK_catalytic PF04263.16 EGC35149.1 - 1.9e-32 111.8 0.0 3.4e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.14 EGC35149.1 - 1.3e-16 60.0 0.5 2.5e-16 59.1 0.5 1.4 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain zf-C3HC4_5 PF17121.5 EGC35149.1 - 0.025 14.4 0.2 0.1 12.5 0.1 1.9 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PP1c_bdg PF10488.9 EGC35149.1 - 0.031 13.7 1.8 0.051 13.0 1.8 1.2 1 0 0 1 1 1 0 Phosphatase-1 catalytic subunit binding region VSP PF03302.13 EGC35150.1 - 0.0038 16.2 0.4 0.0089 14.9 0.4 1.6 1 0 0 1 1 1 1 Giardia variant-specific surface protein ArfGap PF01412.18 EGC35151.1 - 2.6e-25 88.8 0.1 2.6e-25 88.8 0.1 4.7 3 1 0 4 4 4 1 Putative GTPase activating protein for Arf ECH_2 PF16113.5 EGC35152.1 - 2.9e-125 418.2 0.0 3.3e-125 418.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGC35152.1 - 6.3e-29 101.0 0.0 3e-27 95.5 0.0 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase FliG_N PF14842.6 EGC35152.1 - 0.0034 17.9 0.4 0.018 15.6 0.1 2.1 1 1 1 2 2 2 2 FliG N-terminal domain SET PF00856.28 EGC35153.1 - 1.2e-07 32.3 0.1 1.2e-07 32.3 0.1 2.1 2 0 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGC35153.1 - 3.7e-05 24.4 1.2 7.6e-05 23.4 0.3 2.1 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding Kinesin PF00225.23 EGC35154.1 - 1.7e-103 346.1 4.1 1.7e-103 346.1 4.1 3.6 2 2 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGC35154.1 - 1.9e-55 186.9 0.1 1.9e-55 186.9 0.1 3.2 3 0 0 3 3 3 1 Microtubule binding CEP63 PF17045.5 EGC35154.1 - 0.0027 17.6 20.8 0.0061 16.5 20.8 1.7 1 0 0 1 1 1 1 Centrosomal protein of 63 kDa DUF2721 PF11026.8 EGC35154.1 - 9.2 6.2 6.3 3.4 7.6 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2721) RhoGAP PF00620.27 EGC35155.1 - 7e-34 116.8 0.0 8.7e-34 116.5 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain NUDIX PF00293.28 EGC35156.1 - 1.1e-07 31.9 0.0 2.1e-07 31.0 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain DUF1980 PF09323.10 EGC35157.1 - 0.0026 17.7 4.5 0.033 14.1 0.2 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF1980) PS_Dcarbxylase PF02666.15 EGC35157.1 - 0.0031 17.1 5.7 1.7 8.2 0.3 3.1 2 1 1 3 3 3 3 Phosphatidylserine decarboxylase Sigma_reg_N PF13800.6 EGC35157.1 - 0.01 16.1 0.7 0.44 10.9 0.2 2.4 1 1 1 2 2 2 0 Sigma factor regulator N-terminal AA_permease_2 PF13520.6 EGC35157.1 - 0.023 13.6 1.9 0.081 11.7 1.9 1.8 1 1 0 1 1 1 0 Amino acid permease DUF3328 PF11807.8 EGC35157.1 - 4.5 7.0 7.6 35 4.1 7.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) HSP20 PF00011.21 EGC35158.1 - 1.3e-15 57.4 0.6 1.8e-07 31.3 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC35158.1 - 0.0006 19.3 0.1 0.0018 17.8 0.1 2.0 1 1 0 1 1 1 1 HSP20-like domain found in ArsA CS PF04969.16 EGC35158.1 - 0.01 16.8 1.1 0.019 15.9 0.2 1.9 2 1 1 3 3 3 0 CS domain C2 PF00168.30 EGC35159.1 - 9.7e-12 45.1 0.0 2e-11 44.0 0.0 1.4 1 1 0 1 1 1 1 C2 domain C2 PF00168.30 EGC35160.1 - 1.5e-15 57.3 0.1 6.6e-15 55.3 0.1 2.1 1 1 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.9 EGC35160.1 - 2.1e-06 27.9 5.4 0.0032 17.7 0.2 4.1 3 1 1 4 4 4 2 Munc13 (mammalian uncoordinated) homology domain GRAM PF02893.20 EGC35160.1 - 0.013 15.3 1.0 0.013 15.3 1.0 5.5 6 0 0 6 6 6 0 GRAM domain DUF3161 PF11362.8 EGC35160.1 - 0.029 14.4 1.1 0.094 12.7 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3161) THUMP PF02926.17 EGC35160.1 - 3.1 7.9 6.3 1 9.5 0.4 3.2 3 1 1 4 4 4 0 THUMP domain DUF2433 PF10360.9 EGC35160.1 - 6.1 7.0 9.4 3.4 7.8 0.2 4.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2433) AMP-binding PF00501.28 EGC35161.1 - 1.3e-63 215.1 0.0 1.6e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC35161.1 - 1.3e-09 37.8 3.6 1.3e-09 37.8 1.6 2.2 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF2393 PF09624.10 EGC35161.1 - 0.01 15.8 1.8 0.026 14.5 1.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2393) C_Hendra PF16821.5 EGC35163.1 - 0.14 12.0 7.8 0.2 11.5 7.8 1.2 1 0 0 1 1 1 0 C protein from hendra and measles viruses AMP-binding PF00501.28 EGC35164.1 - 1.9e-58 198.1 0.0 2.3e-58 197.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC35164.1 - 4e-10 39.4 1.3 1.5e-09 37.7 1.3 2.1 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding PF00501.28 EGC35165.1 - 7e-64 216.0 0.0 8.5e-64 215.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC35165.1 - 3e-09 36.6 2.8 5.4e-09 35.8 1.4 2.3 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus RT_RNaseH PF17917.1 EGC35166.1 - 8.6e-26 90.3 0.1 1.1e-24 86.7 0.0 2.5 2 0 0 2 2 2 1 RNase H-like domain found in reverse transcriptase RVT_1 PF00078.27 EGC35166.1 - 1.3e-21 77.1 2.2 3.1e-21 75.9 2.2 1.6 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) RT_RNaseH_2 PF17919.1 EGC35166.1 - 8.3e-21 73.9 0.4 3.2e-20 72.0 0.0 2.2 2 1 0 2 2 2 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EGC35166.1 - 5.9e-14 51.9 0.3 1.5e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 Integrase zinc binding domain rve PF00665.26 EGC35166.1 - 2.4e-12 47.1 0.0 5.4e-12 45.9 0.0 1.6 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.24 EGC35166.1 - 3.4e-07 30.1 3.3 1.1e-06 28.5 3.3 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP_2 PF08284.11 EGC35166.1 - 4.3e-05 23.3 0.9 0.00011 22.0 0.9 1.7 1 0 0 1 1 1 1 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGC35166.1 - 0.047 14.3 0.0 0.11 13.1 0.0 1.6 1 0 0 1 1 1 0 Aspartyl protease gag-asp_proteas PF13975.6 EGC35166.1 - 0.17 12.5 0.0 0.44 11.1 0.0 1.8 1 0 0 1 1 1 0 gag-polyprotein putative aspartyl protease AAA_lid_2 PF17863.1 EGC35167.1 - 5.5e-11 42.2 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 AAA lid domain AAA_3 PF07726.11 EGC35167.1 - 9.6e-05 22.3 0.1 0.00024 21.0 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Asp PF00026.23 EGC35168.1 - 8.7e-17 61.5 0.7 2.8e-15 56.6 0.7 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGC35168.1 - 5.7e-12 46.2 3.1 8.3e-12 45.7 3.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGC35168.1 - 2.6e-09 37.1 0.0 2e-08 34.2 0.0 2.3 2 1 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGC35168.1 - 0.00013 22.4 0.0 0.11 13.0 0.0 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Asp_protease_2 PF13650.6 EGC35168.1 - 0.001 19.7 0.0 1.1 10.0 0.0 2.7 3 0 0 3 3 3 2 Aspartyl protease Orn_DAP_Arg_deC PF00278.22 EGC35168.1 - 0.02 15.1 0.1 0.04 14.1 0.1 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase, C-terminal sheet domain DUF3465 PF11948.8 EGC35168.1 - 0.12 12.3 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3465) Asp PF00026.23 EGC35169.1 - 2.4e-19 69.9 2.0 3.7e-15 56.2 0.5 2.1 2 0 0 2 2 2 2 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGC35169.1 - 2e-16 60.2 0.0 3.6e-16 59.3 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGC35169.1 - 1.8e-07 31.6 0.8 8e-07 29.5 0.5 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Ibs_toxin PF13956.6 EGC35169.1 - 0.12 12.4 5.8 0.32 11.0 5.8 1.7 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Asp PF00026.23 EGC35170.1 - 1.3e-20 74.1 1.1 1.3e-20 74.1 1.1 2.0 2 1 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGC35170.1 - 9.7e-14 51.5 0.0 2.3e-13 50.3 0.0 1.6 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGC35170.1 - 2.3e-13 50.8 1.4 2.3e-13 50.8 1.4 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal CBM49 PF09478.10 EGC35170.1 - 0.0058 16.9 4.9 0.0058 16.9 4.9 2.5 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Response_reg PF00072.24 EGC35171.1 - 6.2e-19 68.2 0.7 1.5e-18 67.0 0.0 2.0 2 0 0 2 2 2 1 Response regulator receiver domain BioY PF02632.14 EGC35172.1 - 4.9e-37 127.0 13.4 4.9e-37 127.0 13.4 1.4 2 0 0 2 2 2 1 BioY family PRE_C2HC PF07530.11 EGC35172.1 - 0.14 12.3 0.1 0.24 11.5 0.1 1.4 1 0 0 1 1 1 0 Associated with zinc fingers SLD5_C PF16922.5 EGC35173.1 - 1.2e-10 41.4 0.0 2.2e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 DNA replication complex GINS protein SLD5 C-terminus Sld5 PF05916.11 EGC35173.1 - 0.00011 22.6 1.5 0.00032 21.1 1.1 1.9 1 1 0 1 1 1 1 GINS complex protein Zip PF02535.22 EGC35174.1 - 1.5e-53 182.2 11.1 4.1e-52 177.5 11.1 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Phage_holin_3_3 PF16083.5 EGC35174.1 - 0.00051 20.1 0.1 0.0022 18.1 0.1 2.1 1 0 0 1 1 1 1 LydA holin phage, holin superfamily III Herpes_LMP1 PF05297.11 EGC35174.1 - 0.12 11.6 2.2 0.23 10.6 2.2 1.5 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) RexB PF15968.5 EGC35174.1 - 0.19 12.2 2.8 0.39 11.2 2.8 1.5 1 0 0 1 1 1 0 Membrane-anchored ion channel, Abi component CDK5_activator PF03261.15 EGC35174.1 - 3.8 7.0 13.7 2.9 7.3 11.5 1.8 2 0 0 2 2 2 0 Cyclin-dependent kinase 5 activator protein Ank_4 PF13637.6 EGC35175.1 - 0.00015 22.2 0.1 0.02 15.5 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC35175.1 - 0.0007 20.1 0.4 1.5 9.4 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) UAA PF08449.11 EGC35175.1 - 0.042 13.1 2.1 0.06 12.5 0.5 1.8 2 0 0 2 2 2 0 UAA transporter family DsbC_N PF10411.9 EGC35175.1 - 0.091 12.2 0.0 0.19 11.2 0.0 1.5 1 0 0 1 1 1 0 Disulfide bond isomerase protein N-terminus APAF1_C PF17908.1 EGC35175.1 - 0.46 10.5 5.8 0.55 10.2 0.2 3.5 3 0 0 3 3 3 0 APAF-1 helical domain Erf4 PF10256.9 EGC35177.1 - 0.0046 17.1 0.8 0.032 14.3 0.7 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF829 PF05705.14 EGC35179.1 - 9.7e-33 114.0 0.3 4.2e-32 112.0 0.3 1.8 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.21 EGC35179.1 - 0.031 13.7 0.1 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 Prolyl oligopeptidase family Pkinase PF00069.25 EGC35180.1 - 7.5e-51 173.0 0.0 3.6e-50 170.8 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35180.1 - 1.8e-18 66.8 0.0 7.9e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC35180.1 - 1.8e-05 23.7 0.0 2.9e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC35180.1 - 0.0016 17.8 0.0 0.0073 15.7 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.23 EGC35180.1 - 0.021 14.7 0.1 0.32 10.9 0.1 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC35180.1 - 0.043 13.2 0.0 0.23 10.8 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC35180.1 - 0.093 11.7 0.1 0.25 10.2 0.0 1.6 2 0 0 2 2 2 0 Haspin like kinase domain Sortase PF04203.13 EGC35180.1 - 0.12 12.2 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 Sortase domain Collagen PF01391.18 EGC35181.1 - 0.042 13.6 5.3 0.086 12.6 5.3 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Hamartin PF04388.12 EGC35181.1 - 0.21 10.2 48.0 0.28 9.8 48.0 1.1 1 0 0 1 1 1 0 Hamartin protein Vps23_core PF09454.10 EGC35182.1 - 0.021 14.7 0.1 0.058 13.3 0.1 1.7 1 0 0 1 1 1 0 Vps23 core domain Tho2 PF11262.8 EGC35183.1 - 4e-88 295.5 16.2 4e-88 295.5 16.2 7.8 7 1 0 7 7 7 2 Transcription factor/nuclear export subunit protein 2 THOC2_N PF16134.5 EGC35183.1 - 5.6e-68 230.1 19.9 4.1e-46 157.9 13.2 6.7 5 3 2 7 7 7 2 THO complex subunit 2 N-terminus Thoc2 PF11732.8 EGC35183.1 - 6.8e-25 86.9 0.0 2.4e-24 85.2 0.0 2.1 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Aldedh PF00171.22 EGC35184.1 - 1.2e-179 597.7 0.0 1.4e-179 597.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF4226 PF10774.9 EGC35186.1 - 0.012 15.9 0.0 0.027 14.7 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) TolA_bind_tri PF16331.5 EGC35186.1 - 0.16 12.1 2.1 0.29 11.2 2.1 1.4 1 0 0 1 1 1 0 TolA binding protein trimerisation EGF_2 PF07974.13 EGC35187.1 - 3.5e-05 24.1 11.3 9.6e-05 22.7 11.3 1.7 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.24 EGC35187.1 - 0.00022 21.2 19.1 0.004 17.2 3.1 4.1 4 1 0 4 4 4 2 IPT/TIG domain EGF_Tenascin PF18720.1 EGC35187.1 - 0.062 13.4 6.4 0.23 11.6 6.4 2.0 1 0 0 1 1 1 0 Tenascin EGF domain EGF PF00008.27 EGC35187.1 - 0.086 13.2 9.2 0.19 12.0 9.2 1.7 1 0 0 1 1 1 0 EGF-like domain Syndecan PF01034.20 EGC35187.1 - 0.28 11.1 1.3 0.66 9.9 1.3 1.6 1 0 0 1 1 1 0 Syndecan domain hEGF PF12661.7 EGC35187.1 - 0.33 11.7 9.3 0.89 10.3 9.3 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_alliinase PF04863.13 EGC35187.1 - 0.57 10.6 7.8 1.7 9.1 7.8 1.8 1 1 0 1 1 1 0 Alliinase EGF-like domain Syja_N PF02383.18 EGC35188.1 - 4.5e-83 279.2 0.1 4.5e-83 279.2 0.1 2.1 2 0 0 2 2 2 1 SacI homology domain YpjP PF14005.6 EGC35188.1 - 0.22 11.6 6.0 6.4 6.8 3.2 3.5 3 0 0 3 3 3 0 YpjP-like protein RB_A PF01858.17 EGC35189.1 - 2.3e-39 135.3 4.4 2.3e-39 135.3 4.4 4.1 5 0 0 5 5 5 2 Retinoblastoma-associated protein A domain DUF3452 PF11934.8 EGC35189.1 - 8.3e-32 109.6 0.3 8.3e-32 109.6 0.3 4.9 7 0 0 7 7 7 1 Domain of unknown function (DUF3452) RB_B PF01857.20 EGC35189.1 - 2.4e-19 69.7 1.8 2.4e-19 69.7 1.8 3.4 3 0 0 3 3 3 1 Retinoblastoma-associated protein B domain Lysine_decarbox PF03641.14 EGC35190.1 - 1.9e-40 138.0 0.0 2.4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Possible lysine decarboxylase LDcluster4 PF18306.1 EGC35190.1 - 6.5e-18 64.8 0.8 7.8e-18 64.6 0.8 1.1 1 0 0 1 1 1 1 SLOG cluster4 family 7tm_3 PF00003.22 EGC35191.1 - 6e-23 81.8 26.0 8.6e-23 81.3 26.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC35191.1 - 2.1e-15 56.5 1.8 2.1e-15 56.5 1.8 1.4 2 0 0 2 2 2 1 ABC transporter substrate-binding protein PnrA-like FNIP PF05725.12 EGC35192.1 - 3.6e-77 254.3 23.6 6.7e-14 51.8 0.9 6.6 6 0 0 6 6 6 6 FNIP Repeat Phage_min_tail PF05939.13 EGC35192.1 - 0.036 14.4 0.0 15 6.0 0.0 4.4 3 1 1 5 5 5 0 Phage minor tail protein LRR_1 PF00560.33 EGC35192.1 - 0.25 12.0 8.9 1.2e+02 3.8 0.1 6.0 5 1 0 5 5 5 0 Leucine Rich Repeat Kelch_4 PF13418.6 EGC35194.1 - 1.4e-44 149.8 14.3 5.3e-10 39.1 0.1 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC35194.1 - 4.1e-44 147.9 11.2 1.8e-08 33.8 0.0 6.6 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.6 EGC35194.1 - 1.3e-38 130.0 13.0 9.6e-07 28.9 0.1 6.4 4 1 2 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC35194.1 - 1.1e-37 126.5 6.1 3.3e-07 30.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC35194.1 - 1.1e-36 124.4 14.5 1e-05 25.7 0.0 7.4 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC35194.1 - 2e-34 117.0 8.2 1.3e-05 25.0 0.2 6.4 6 0 0 6 6 6 6 Kelch motif Pex26 PF07163.12 EGC35194.1 - 0.0039 16.5 0.1 0.0065 15.8 0.1 1.2 1 0 0 1 1 1 1 Pex26 protein WRNPLPNID PF15017.6 EGC35194.1 - 5.7 7.9 8.8 0.28 12.1 2.8 2.0 2 0 0 2 2 2 0 Putative WW-binding domain and destruction box Aldedh PF00171.22 EGC35195.1 - 8.9e-180 598.1 0.0 1e-179 597.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGC35195.1 - 0.1 12.0 0.0 0.83 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cyclin_N PF00134.23 EGC35196.1 - 3.7e-15 55.8 1.8 3.7e-15 55.8 1.8 1.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC35196.1 - 5.5e-05 23.2 0.1 0.19 11.9 0.1 2.3 2 0 0 2 2 2 2 Cyclin, C-terminal domain COX2_TM PF02790.15 EGC35196.1 - 0.005 17.0 0.1 0.0098 16.0 0.1 1.4 1 0 0 1 1 1 1 Cytochrome C oxidase subunit II, transmembrane domain Cyclin_C_2 PF16899.5 EGC35196.1 - 0.0051 17.2 0.1 0.052 13.9 0.0 2.5 2 1 0 2 2 2 1 Cyclin C-terminal domain G6PD_bact PF10786.9 EGC35196.1 - 0.022 14.3 0.1 0.045 13.3 0.1 1.4 1 0 0 1 1 1 0 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) FKBP_C PF00254.28 EGC35197.1 - 5.3e-18 65.1 0.0 5.7e-18 65.0 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DHR-2 PF06920.13 EGC35198.1 - 1.7e-173 578.1 11.5 3e-173 577.3 11.5 1.4 1 0 0 1 1 1 1 Dock homology region 2 DOCK-C2 PF14429.6 EGC35198.1 - 1.6e-38 132.5 8.3 4.9e-38 130.9 0.7 3.9 3 1 0 3 3 3 2 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 EGC35198.1 - 0.001 19.5 0.0 0.0036 17.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF3398) CDP-OH_P_transf PF01066.21 EGC35199.1 - 2.3e-15 57.1 0.1 2.3e-15 57.1 0.1 3.2 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase EpsG PF14897.6 EGC35199.1 - 8.3 5.6 36.4 0.43 9.8 0.5 2.9 2 1 1 3 3 3 0 EpsG family ABC_tran PF00005.27 EGC35200.1 - 4.4e-23 82.3 0.0 7.3e-15 55.7 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGC35200.1 - 2.2e-11 43.6 1.3 0.00023 20.7 0.1 3.0 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGC35200.1 - 1.2e-05 25.3 0.3 0.11 12.2 0.1 3.3 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGC35200.1 - 0.00085 19.3 0.0 0.0019 18.1 0.0 1.5 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EGC35200.1 - 0.0056 17.1 0.0 0.014 15.9 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TsaE PF02367.17 EGC35200.1 - 0.034 14.2 0.2 0.084 12.9 0.1 1.7 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SRP54 PF00448.22 EGC35200.1 - 0.038 13.6 0.1 0.07 12.7 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_7 PF12775.7 EGC35200.1 - 0.038 13.5 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_22 PF13401.6 EGC35200.1 - 0.039 14.2 0.0 0.079 13.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC35200.1 - 0.045 14.2 0.2 0.092 13.2 0.2 1.6 1 0 0 1 1 1 0 AAA domain AAA_15 PF13175.6 EGC35200.1 - 0.051 13.3 1.7 0.9 9.2 0.3 2.8 3 1 0 3 3 3 0 AAA ATPase domain Zeta_toxin PF06414.12 EGC35200.1 - 0.069 12.4 0.1 0.21 10.9 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin NACHT PF05729.12 EGC35200.1 - 0.073 13.0 0.0 0.14 12.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.6 EGC35200.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC35200.1 - 0.11 12.2 0.1 0.31 10.7 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC35200.1 - 0.12 12.5 0.0 0.29 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain DUF575 PF04746.12 EGC35200.1 - 0.13 12.6 0.0 0.27 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF575) AAA_16 PF13191.6 EGC35200.1 - 0.16 12.4 0.0 0.29 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ACOX PF01756.19 EGC35201.1 - 2.1e-42 144.7 3.7 2.2e-42 144.6 1.0 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGC35201.1 - 2.1e-18 67.0 0.1 7.2e-18 65.3 0.1 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.19 EGC35201.1 - 3.3e-11 43.2 0.0 5.7e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ArAE_1_C PF11728.8 EGC35201.1 - 2.5 8.1 8.8 0.35 10.9 1.3 3.1 3 0 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain YqzH PF14164.6 EGC35202.1 - 0.078 13.1 0.9 0.83 9.8 0.0 2.3 2 0 0 2 2 2 0 YqzH-like protein Lung_7-TM_R PF06814.13 EGC35204.1 - 0.0013 18.1 2.7 0.0014 17.9 2.7 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor Lung_7-TM_R PF06814.13 EGC35205.1 - 3.7e-12 46.1 1.5 4.6e-12 45.8 1.5 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Prp19 PF08606.11 EGC35206.1 - 0.031 14.3 0.1 0.13 12.3 0.1 2.1 1 0 0 1 1 1 0 Prp19/Pso4-like ZapB PF06005.12 EGC35206.1 - 0.12 12.8 26.8 0.31 11.5 5.9 3.0 2 1 0 2 2 2 0 Cell division protein ZapB APG6_N PF17675.1 EGC35206.1 - 0.56 10.7 15.0 1 9.9 3.8 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region Telomerase_RBD PF12009.8 EGC35206.1 - 2 8.5 6.0 2.4 8.3 2.1 2.3 2 0 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain bZIP_1 PF00170.21 EGC35206.1 - 4.4 7.5 18.5 7.3 6.8 5.0 3.4 2 1 1 3 3 3 0 bZIP transcription factor Pkinase PF00069.25 EGC35207.1 - 2e-16 60.2 0.2 2.6e-16 59.8 0.2 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35207.1 - 1.3e-05 24.6 0.0 2.1e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35208.1 - 3.3e-21 75.8 7.5 3.3e-21 75.8 7.5 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35208.1 - 1.4e-07 31.0 0.7 3e-07 30.0 0.7 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC35208.1 - 0.012 15.0 0.1 0.024 14.0 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tmemb_14 PF03647.13 EGC35209.1 - 0.0097 16.6 3.6 0.062 14.0 3.6 1.9 1 1 0 1 1 1 1 Transmembrane proteins 14C MerC PF03203.14 EGC35209.1 - 0.14 12.7 0.9 0.38 11.2 0.6 1.8 1 1 1 2 2 2 0 MerC mercury resistance protein Cnn_1N PF07989.11 EGC35210.1 - 0.012 15.8 3.7 0.014 15.6 3.7 1.2 1 0 0 1 1 1 0 Centrosomin N-terminal motif 1 RecG_N PF17190.4 EGC35210.1 - 0.076 13.8 1.4 0.084 13.6 1.4 1.0 1 0 0 1 1 1 0 RecG N-terminal helical domain Uso1_p115_C PF04871.13 EGC35211.1 - 0.00025 21.4 0.6 0.24 11.8 0.2 2.2 1 1 1 2 2 2 2 Uso1 / p115 like vesicle tethering protein, C terminal region IL15 PF02372.15 EGC35211.1 - 0.0061 16.6 1.8 0.0061 16.6 1.8 1.9 1 1 0 2 2 2 1 Interleukin 15 Filament PF00038.21 EGC35211.1 - 0.01 15.5 4.6 0.24 10.9 3.4 2.1 1 1 1 2 2 2 0 Intermediate filament protein FlaC_arch PF05377.11 EGC35211.1 - 0.011 16.1 8.3 0.55 10.7 1.3 3.0 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Atg14 PF10186.9 EGC35211.1 - 0.027 13.6 7.0 0.03 13.4 7.0 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF5082 PF16888.5 EGC35211.1 - 0.034 14.4 9.3 0.37 11.1 1.6 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF5082) YlqD PF11068.8 EGC35211.1 - 0.038 14.4 4.6 0.19 12.1 0.5 2.1 1 1 1 2 2 2 0 YlqD protein Herpes_BLRF2 PF05812.12 EGC35211.1 - 0.056 13.6 0.3 0.22 11.7 0.1 2.0 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein APG6_N PF17675.1 EGC35211.1 - 0.062 13.8 4.2 0.2 12.2 4.2 1.8 1 1 0 1 1 1 0 Apg6 coiled-coil region TPD52 PF04201.15 EGC35211.1 - 0.088 12.4 4.9 1.7 8.2 0.7 2.2 2 0 0 2 2 2 0 Tumour protein D52 family COG5 PF10392.9 EGC35211.1 - 0.12 12.6 5.2 0.28 11.3 0.3 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF4618 PF15397.6 EGC35211.1 - 0.12 11.8 7.9 1.1 8.6 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Golgin_A5 PF09787.9 EGC35211.1 - 0.13 11.7 6.7 0.22 10.9 6.3 1.5 1 1 0 1 1 1 0 Golgin subfamily A member 5 PRKG1_interact PF15898.5 EGC35211.1 - 0.17 12.8 3.9 0.097 13.6 0.7 2.1 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain CENP-F_leu_zip PF10473.9 EGC35211.1 - 0.17 11.9 10.3 0.17 11.9 2.0 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 bZIP_2 PF07716.15 EGC35211.1 - 0.24 11.5 4.3 6 7.0 2.1 2.9 2 1 0 2 2 2 0 Basic region leucine zipper SlyX PF04102.12 EGC35211.1 - 0.27 11.9 2.9 15 6.3 0.1 2.8 2 1 1 3 3 3 0 SlyX YabA PF06156.13 EGC35211.1 - 0.52 11.0 9.8 1.8 9.2 1.5 2.4 2 1 0 2 2 2 0 Initiation control protein YabA DUF724 PF05266.14 EGC35211.1 - 0.59 9.9 6.7 0.6 9.9 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF724) Spc24 PF08286.11 EGC35211.1 - 0.96 9.7 8.3 5.9 7.2 1.2 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 YtxH PF12732.7 EGC35211.1 - 1.6 9.3 4.3 7.8 7.1 0.1 2.3 2 0 0 2 2 2 0 YtxH-like protein Lebercilin PF15619.6 EGC35211.1 - 1.6 8.3 10.8 1.1 8.8 1.1 2.5 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease PhoU PF01895.19 EGC35211.1 - 3 8.3 7.7 1.8e+02 2.7 7.6 2.5 1 1 0 1 1 1 0 PhoU domain DUF4200 PF13863.6 EGC35211.1 - 4.4 7.7 13.6 2.8 8.4 0.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) HMMR_C PF15908.5 EGC35211.1 - 4.6 7.5 10.3 1.1 9.5 0.8 2.2 1 1 1 2 2 2 0 Hyaluronan mediated motility receptor C-terminal DivIC PF04977.15 EGC35211.1 - 5.3 6.9 9.4 3.8 7.3 1.6 2.7 2 1 0 2 2 2 0 Septum formation initiator Fib_alpha PF08702.10 EGC35211.1 - 6.1 7.0 10.9 7 6.8 3.2 2.4 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Csm1_N PF18504.1 EGC35211.1 - 7.1 7.1 9.0 3.5 8.0 1.5 2.9 2 1 1 3 3 3 0 Csm1 N-terminal domain Tektin PF03148.14 EGC35211.1 - 8.4 5.0 13.3 3 6.5 2.6 2.8 2 1 0 2 2 2 0 Tektin family DUF4094 PF13334.6 EGC35211.1 - 9.7 6.7 6.7 3.6 8.1 0.1 2.7 2 1 0 3 3 3 0 Domain of unknown function (DUF4094) Med1 PF10744.9 EGC35212.1 - 6.2e-19 68.3 14.2 6.2e-19 68.3 14.2 2.5 1 1 1 2 2 2 1 Mediator of RNA polymerase II transcription subunit 1 Usp PF00582.26 EGC35213.1 - 0.00057 20.4 0.3 0.07 13.6 0.0 2.9 2 1 0 2 2 2 1 Universal stress protein family I_LWEQ PF01608.17 EGC35213.1 - 2.4 8.4 5.0 0.86 9.8 2.0 1.7 2 0 0 2 2 2 0 I/LWEQ domain Peptidase_C1 PF00112.23 EGC35214.1 - 4.3e-72 242.8 2.6 4.3e-72 242.8 2.6 1.8 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC35214.1 - 8.4e-12 45.3 8.7 1.5e-11 44.6 8.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PP-binding PF00550.25 EGC35216.1 - 1.4e-05 25.4 0.1 1.4e-05 25.3 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Dickkopf_N PF04706.12 EGC35217.1 - 2.6e-09 37.4 8.3 2.6e-09 37.4 8.3 6.5 4 1 2 6 6 6 2 Dickkopf N-terminal cysteine-rich region Macoilin PF09726.9 EGC35217.1 - 7.9 4.9 11.9 11 4.4 11.9 1.2 1 0 0 1 1 1 0 Macoilin family SecA_DEAD PF07517.14 EGC35218.1 - 0.0089 15.4 0.1 0.01 15.2 0.1 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain TTL PF03133.15 EGC35218.1 - 0.014 14.5 0.4 0.019 14.1 0.4 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family PdaC PF13739.6 EGC35218.1 - 0.13 13.3 5.4 0.23 12.4 5.4 1.4 1 0 0 1 1 1 0 Deacetylase PdaC TrmK PF04816.12 EGC35218.1 - 0.22 11.0 3.2 8.3 5.9 0.0 2.2 2 1 0 2 2 2 0 tRNA (adenine(22)-N(1))-methyltransferase Pkinase PF00069.25 EGC35219.1 - 1.1e-21 77.4 2.9 1.3e-15 57.6 1.5 2.7 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35219.1 - 1.4e-20 73.6 0.0 7.9e-20 71.2 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC35219.1 - 0.013 14.8 0.6 0.026 13.9 0.6 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.18 EGC35220.1 - 1e-120 402.3 0.1 1e-120 402.3 0.1 1.9 2 0 0 2 2 2 1 Beige/BEACH domain DUF4704 PF15787.5 EGC35220.1 - 1.8e-59 201.3 9.6 1.8e-59 201.3 9.6 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF4704) PH_BEACH PF14844.6 EGC35220.1 - 4.3e-28 97.4 3.0 4.4e-28 97.3 0.0 2.7 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.6 EGC35220.1 - 1.2e-15 58.0 0.0 3.7e-15 56.4 0.0 1.9 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily DUF4800 PF16057.5 EGC35220.1 - 3.2e-14 52.8 1.6 3.2e-14 52.8 1.6 2.8 3 0 0 3 3 3 1 Domain of unknown function (DUF4800) WD40 PF00400.32 EGC35220.1 - 5e-14 52.5 9.1 5.9e-05 23.8 0.1 5.7 5 0 0 5 5 5 4 WD domain, G-beta repeat DUF1088 PF06469.11 EGC35220.1 - 1.7e-05 24.6 2.0 4e-05 23.4 2.0 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) ANAPC4_WD40 PF12894.7 EGC35220.1 - 0.0041 17.4 0.1 2.2 8.6 0.0 3.8 2 2 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain Pentaxin PF00354.17 EGC35220.1 - 0.0044 16.7 0.1 0.0044 16.7 0.1 2.6 3 0 0 3 3 3 1 Pentaxin family GRAM PF02893.20 EGC35220.1 - 0.021 14.7 0.2 0.021 14.7 0.2 3.0 3 0 0 3 3 3 0 GRAM domain DALR_2 PF09190.11 EGC35220.1 - 0.39 11.2 2.0 2.5 8.7 0.0 3.1 3 0 0 3 3 3 0 DALR domain Ras PF00071.22 EGC35221.1 - 2e-50 170.5 0.1 4e-50 169.6 0.1 1.5 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35221.1 - 1.9e-21 76.5 1.1 6.9e-21 74.7 0.0 2.3 3 0 0 3 3 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35221.1 - 3.8e-11 42.8 0.0 5.9e-11 42.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC35221.1 - 6.8e-07 29.0 0.4 1.3e-06 28.2 0.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC35221.1 - 1.1e-06 28.7 0.8 4.4e-06 26.8 0.0 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC35221.1 - 2.8e-06 27.3 0.1 0.055 13.4 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGC35221.1 - 0.00081 18.8 0.1 0.0014 18.1 0.1 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.18 EGC35221.1 - 0.0048 16.4 0.1 0.012 15.1 0.1 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.6 EGC35221.1 - 0.014 15.8 0.0 0.018 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.12 EGC35221.1 - 0.02 14.4 0.0 0.079 12.5 0.0 2.0 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain AAA_7 PF12775.7 EGC35221.1 - 0.026 14.0 0.0 0.056 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region TniB PF05621.11 EGC35221.1 - 0.076 12.4 0.5 1.5 8.1 0.0 2.5 3 0 0 3 3 3 0 Bacterial TniB protein ABC2_membrane_3 PF12698.7 EGC35221.1 - 3.4 6.7 6.9 4.1 6.4 6.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Ku_PK_bind PF08785.11 EGC35222.1 - 0.013 15.6 1.0 0.03 14.5 1.0 1.6 1 0 0 1 1 1 0 Ku C terminal domain like CDC45 PF02724.14 EGC35222.1 - 0.34 9.2 9.9 0.39 8.9 9.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1840 PF08895.11 EGC35222.1 - 0.39 11.1 5.1 2.2 8.6 4.2 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) DUF2115 PF09888.9 EGC35222.1 - 0.8 10.2 8.2 0.32 11.5 0.8 2.2 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Syntaxin-6_N PF09177.11 EGC35222.1 - 2 9.0 12.6 0.082 13.5 2.9 2.4 1 1 1 2 2 2 0 Syntaxin 6, N-terminal RRN3 PF05327.11 EGC35222.1 - 5.3 5.5 12.2 6.4 5.2 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 SNF2_N PF00176.23 EGC35223.1 - 4e-37 127.7 0.2 4e-37 127.7 0.2 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC35223.1 - 7.8e-17 61.6 0.0 7.8e-17 61.6 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain PRA1 PF03208.19 EGC35224.1 - 0.4 10.3 2.5 0.44 10.2 2.5 1.1 1 0 0 1 1 1 0 PRA1 family protein ketoacyl-synt PF00109.26 EGC35225.1 - 2.3e-64 217.4 0.0 3.9e-64 216.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC35225.1 - 2e-44 152.4 0.0 5.1e-44 151.1 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC35225.1 - 5e-33 113.6 0.0 5.8e-32 110.2 0.0 2.4 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC35225.1 - 1e-24 87.4 0.1 2.3e-24 86.3 0.1 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC35225.1 - 3.4e-18 66.2 0.0 3.4e-18 66.2 0.0 4.1 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC35225.1 - 8.5e-18 64.6 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC35225.1 - 6.8e-17 61.9 0.6 2.3e-16 60.2 0.2 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC35225.1 - 1.7e-09 38.8 0.0 1e-08 36.3 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EGC35225.1 - 9.6e-07 28.4 0.0 2.5e-06 27.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 EGC35225.1 - 1.7e-06 27.9 0.1 4.3e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC35225.1 - 5.2e-05 23.8 0.0 0.0002 21.9 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC35225.1 - 5.3e-05 23.1 0.0 0.00013 21.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC35225.1 - 0.0032 17.8 0.2 0.0077 16.6 0.2 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGC35225.1 - 0.026 14.3 5.1 0.17 11.6 0.0 4.2 3 0 0 3 3 3 0 Methyltransferase domain DUF1430 PF07242.11 EGC35225.1 - 0.029 14.6 0.3 0.15 12.3 0.3 2.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) GDP_Man_Dehyd PF16363.5 EGC35225.1 - 0.15 11.4 3.4 0.049 13.0 0.4 1.7 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase Methyltransf_16 PF10294.9 EGC35226.1 - 1.3e-20 73.9 0.2 2.8e-20 72.8 0.0 1.7 2 0 0 2 2 2 1 Lysine methyltransferase Methyltransf_31 PF13847.6 EGC35226.1 - 5.6e-05 23.0 0.1 0.00027 20.8 0.0 2.1 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC35226.1 - 0.00015 22.5 1.4 0.001 19.8 0.0 2.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC35226.1 - 0.00054 19.8 0.0 0.0017 18.2 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC35226.1 - 0.0011 19.6 0.0 0.0055 17.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC35226.1 - 0.003 18.2 0.0 0.012 16.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC35226.1 - 0.0037 16.8 0.0 0.0089 15.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGC35226.1 - 0.022 14.2 0.0 0.058 12.8 0.0 1.6 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) 6PF2K PF01591.18 EGC35227.1 - 2.4e-79 265.7 0.0 3.6e-79 265.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGC35227.1 - 4.9e-37 127.5 0.0 8.9e-37 126.7 0.0 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGC35227.1 - 1.6e-05 25.1 0.0 3.5e-05 24.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain RasGEF PF00617.19 EGC35228.1 - 3.1e-09 37.3 0.7 6.5e-09 36.2 0.0 1.7 2 0 0 2 2 2 1 RasGEF domain MciZ PF13072.6 EGC35228.1 - 0.042 13.7 0.7 0.072 12.9 0.7 1.4 1 0 0 1 1 1 0 Mother cell inhibitor of FtsZ ELO PF01151.18 EGC35229.1 - 1.3e-49 169.0 23.1 3.6e-25 88.9 11.6 2.1 1 1 1 2 2 2 2 GNS1/SUR4 family Pkinase PF00069.25 EGC35230.1 - 4e-75 252.6 0.0 5.5e-75 252.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35230.1 - 3.3e-39 134.7 0.0 4.4e-39 134.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGC35230.1 - 5.8e-21 75.0 0.3 1.4e-20 73.8 0.3 1.7 1 0 0 1 1 1 1 PH domain PH_3 PF14593.6 EGC35230.1 - 4.3e-08 33.2 0.3 4.3e-08 33.2 0.3 1.9 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGC35230.1 - 4.2e-06 27.1 3.8 0.00022 21.6 1.8 2.8 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.6 EGC35230.1 - 9e-06 25.9 0.8 2.4e-05 24.5 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain Pkinase_C PF00433.24 EGC35230.1 - 4.2e-05 24.2 0.2 8.1e-05 23.2 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_9 PF15410.6 EGC35230.1 - 0.00019 21.8 1.5 0.0016 18.8 0.2 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 EGC35230.1 - 0.00042 20.6 0.0 0.00086 19.6 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.6 EGC35230.1 - 0.0015 17.9 0.1 0.056 12.8 0.0 2.3 1 1 0 2 2 2 1 Kinase-like FTA2 PF13095.6 EGC35230.1 - 0.0022 17.7 0.1 0.76 9.4 0.1 2.8 3 0 0 3 3 3 1 Kinetochore Sim4 complex subunit FTA2 Pkinase_fungal PF17667.1 EGC35230.1 - 0.0053 15.6 0.0 0.0083 14.9 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Ribosomal_S10 PF00338.22 EGC35230.1 - 0.0094 16.2 0.0 0.35 11.1 0.1 2.4 2 0 0 2 2 2 1 Ribosomal protein S10p/S20e PH_17 PF18012.1 EGC35230.1 - 0.04 13.6 0.0 0.068 12.9 0.0 1.4 1 0 0 1 1 1 0 PH domain APH PF01636.23 EGC35230.1 - 0.13 12.2 0.0 0.9 9.4 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC35230.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PNP_UDP_1 PF01048.20 EGC35231.1 - 3.5e-32 111.5 0.0 4.2e-32 111.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily RuvX PF03652.15 EGC35231.1 - 0.056 13.8 0.0 0.086 13.2 0.0 1.2 1 0 0 1 1 1 0 Holliday junction resolvase ABC2_membrane PF01061.24 EGC35232.1 - 1.9e-37 128.8 23.2 1.9e-37 128.8 23.2 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC35232.1 - 5e-26 91.9 0.0 8.5e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_25 PF13481.6 EGC35232.1 - 3.4e-05 23.5 0.1 0.00039 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.6 EGC35232.1 - 9.6e-05 22.3 0.0 0.064 13.0 0.1 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC35232.1 - 0.00014 21.6 0.1 0.00028 20.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC35232.1 - 0.00014 21.8 0.8 0.00033 20.6 0.8 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_16 PF13191.6 EGC35232.1 - 0.00067 20.1 0.0 0.0012 19.2 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_30 PF13604.6 EGC35232.1 - 0.0018 18.1 0.0 0.0029 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.19 EGC35232.1 - 0.0032 16.9 0.0 0.11 11.9 0.0 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGC35232.1 - 0.0033 17.7 0.0 0.048 13.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGC35232.1 - 0.0079 16.7 0.0 0.019 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGC35232.1 - 0.077 12.9 1.2 0.22 11.4 1.0 1.9 1 1 0 1 1 1 0 Rad17 P-loop domain IstB_IS21 PF01695.17 EGC35232.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGC35232.1 - 0.15 11.9 0.3 0.36 10.7 0.1 1.7 2 0 0 2 2 2 0 NACHT domain Cytidylate_kin PF02224.18 EGC35232.1 - 0.17 11.6 2.4 0.2 11.4 0.1 2.1 2 1 0 2 2 2 0 Cytidylate kinase AAA_28 PF13521.6 EGC35232.1 - 0.19 12.0 0.2 0.32 11.2 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.6 EGC35232.1 - 0.23 11.6 0.1 0.41 10.8 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC35232.1 - 0.61 10.5 0.1 0.61 10.5 0.1 2.4 1 1 1 2 2 2 0 AAA domain PHO4 PF01384.20 EGC35232.1 - 2.3 7.2 5.9 4.4 6.3 5.4 1.5 1 1 0 1 1 1 0 Phosphate transporter family ABC2_membrane_3 PF12698.7 EGC35232.1 - 5.4 6.0 29.7 4.6 6.3 25.4 2.3 1 1 1 2 2 2 0 ABC-2 family transporter protein LSM14 PF12701.7 EGC35233.1 - 9.5e-30 102.5 0.1 2.7e-29 101.1 0.1 1.8 1 0 0 1 1 1 1 Scd6-like Sm domain FDF PF09532.10 EGC35233.1 - 7.4e-10 39.6 6.4 7.4e-10 39.6 6.4 4.2 3 1 1 4 4 4 1 FDF domain SM-ATX PF14438.6 EGC35233.1 - 6e-07 29.5 0.0 1.8e-06 28.0 0.0 1.8 1 0 0 1 1 1 1 Ataxin 2 SM domain Acetyltransf_10 PF13673.7 EGC35234.1 - 3.4e-10 39.9 0.0 5.1e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC35234.1 - 6.4e-10 39.3 0.0 9.3e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC35234.1 - 4.3e-09 36.7 0.0 1.7e-08 34.7 0.0 1.8 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC35234.1 - 3.4e-05 23.7 0.0 9.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.6 EGC35234.1 - 0.011 15.8 0.0 0.052 13.7 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase LZ3wCH PF18517.1 EGC35235.1 - 3.4e-10 39.9 3.7 3.4e-10 39.9 3.7 2.4 2 0 0 2 2 2 1 Leucine zipper with capping helix domain TBPIP PF07106.13 EGC35235.1 - 2e-09 37.2 0.7 2e-09 37.2 0.7 2.7 2 0 0 2 2 2 1 TBPIP/Hop2 winged helix domain DUF4600 PF15372.6 EGC35235.1 - 0.0024 18.3 11.6 0.0024 18.3 11.6 3.3 2 1 1 3 3 3 2 Domain of unknown function (DUF4600) DUF1664 PF07889.12 EGC35235.1 - 0.0047 16.9 4.2 0.0047 16.9 4.2 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) bZIP_2 PF07716.15 EGC35235.1 - 0.019 15.0 3.4 0.019 15.0 3.4 4.6 4 2 1 5 5 4 0 Basic region leucine zipper Ax_dynein_light PF10211.9 EGC35235.1 - 0.082 12.8 21.1 0.022 14.7 12.3 2.8 1 1 1 2 2 2 0 Axonemal dynein light chain Mnd1 PF03962.15 EGC35235.1 - 0.11 12.8 4.6 2 8.8 0.1 2.8 2 0 0 2 2 2 0 Mnd1 HTH domain DASH_Hsk3 PF08227.11 EGC35235.1 - 0.13 12.6 0.2 0.13 12.6 0.2 3.0 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like Apolipoprotein PF01442.18 EGC35235.1 - 0.22 11.4 16.6 6.9 6.5 13.6 2.7 1 1 1 2 2 2 0 Apolipoprotein A1/A4/E domain Prominin PF05478.11 EGC35235.1 - 0.32 8.9 7.8 0.41 8.6 7.8 1.3 1 0 0 1 1 1 0 Prominin Jnk-SapK_ap_N PF09744.9 EGC35235.1 - 0.48 10.6 29.4 0.027 14.7 17.2 2.9 2 1 1 3 3 3 0 JNK_SAPK-associated protein-1 FUSC PF04632.12 EGC35235.1 - 0.53 8.7 2.0 0.67 8.4 2.0 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family Lzipper-MIP1 PF14389.6 EGC35235.1 - 0.59 10.5 12.5 0.2 11.9 8.3 2.3 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 DUF2935 PF11155.8 EGC35235.1 - 0.71 10.2 6.6 1 9.7 4.8 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) UPF0154 PF03672.13 EGC35235.1 - 0.84 9.7 6.0 0.45 10.6 3.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0154) Phasin PF05597.11 EGC35235.1 - 0.89 9.6 11.3 7.8 6.5 4.2 2.6 2 1 0 3 3 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) APG6_N PF17675.1 EGC35235.1 - 0.95 10.0 25.3 0.27 11.8 21.3 2.1 2 1 0 2 2 2 0 Apg6 coiled-coil region V_ATPase_I PF01496.19 EGC35235.1 - 1.1 7.1 11.3 1.3 6.9 11.3 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF948 PF06103.11 EGC35235.1 - 1.5 9.1 7.3 5.8 7.2 7.3 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3793 PF12672.7 EGC35235.1 - 1.5 8.8 6.3 0.4 10.7 2.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF3793) YlqD PF11068.8 EGC35235.1 - 2.7 8.4 22.3 0.54 10.6 11.2 2.7 1 1 1 2 2 2 0 YlqD protein ACR_tran PF00873.19 EGC35235.1 - 2.9 5.4 4.2 3.3 5.2 4.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FlaG PF03646.15 EGC35235.1 - 3.7 7.8 17.6 0.26 11.5 0.2 3.6 1 1 3 4 4 4 0 FlaG protein DUF4407 PF14362.6 EGC35235.1 - 3.7 6.8 13.2 5.6 6.2 13.2 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) Allexi_40kDa PF05549.11 EGC35235.1 - 4.6 6.7 10.2 3 7.3 8.5 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein CorA PF01544.18 EGC35235.1 - 5.5 6.2 11.8 2.1 7.6 7.5 1.9 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein FapA PF03961.13 EGC35235.1 - 5.8 5.4 15.2 3.9 6.0 13.5 1.5 1 1 0 1 1 1 0 Flagellar Assembly Protein A DUF4164 PF13747.6 EGC35235.1 - 8.2 6.8 13.4 1.8 8.9 6.9 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) Strep_his_triad PF04270.13 EGC35236.1 - 0.25 11.4 0.3 0.25 11.4 0.3 2.0 2 1 0 2 2 2 0 Streptococcal histidine triad protein DEC-1_N PF04625.13 EGC35237.1 - 0.88 8.5 11.2 0.22 10.5 7.9 1.5 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region DEAD PF00270.29 EGC35239.1 - 2.1e-49 167.7 0.1 2.6e-48 164.1 0.0 2.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC35239.1 - 5.1e-28 97.6 0.5 6e-27 94.2 0.2 2.4 1 1 1 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC35239.1 - 0.0002 21.4 0.2 0.0033 17.4 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SR-25 PF10500.9 EGC35239.1 - 0.13 11.9 18.8 0.21 11.1 18.8 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Tim54 PF11711.8 EGC35239.1 - 0.55 9.0 8.2 0.84 8.4 8.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 HAP2-GCS1 PF10699.9 EGC35240.1 - 0.00036 20.5 0.1 0.00036 20.5 0.1 2.6 3 0 0 3 3 3 1 Male gamete fusion factor SKG6 PF08693.10 EGC35240.1 - 0.33 10.4 2.5 0.97 8.9 2.5 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Toxin_5 PF05294.13 EGC35240.1 - 5.4 7.5 8.6 12 6.4 8.6 1.6 1 0 0 1 1 1 0 Scorpion short toxin FH2 PF02181.23 EGC35241.1 - 1.1e-89 301.2 4.4 1.1e-89 301.2 4.4 2.5 2 1 0 2 2 2 1 Formin Homology 2 Domain Drf_GBD PF06371.13 EGC35241.1 - 5.7e-35 120.6 4.8 5.7e-35 120.6 4.8 2.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGC35241.1 - 6.9e-34 117.2 1.1 6.9e-34 117.2 1.1 3.2 2 1 0 2 2 2 1 Diaphanous FH3 Domain ATG16 PF08614.11 EGC35241.1 - 0.0087 16.3 17.7 0.0087 16.3 17.7 3.7 4 0 0 4 4 4 1 Autophagy protein 16 (ATG16) PAH PF02671.21 EGC35241.1 - 0.031 14.4 0.3 3.6 7.8 0.0 3.0 2 0 0 2 2 2 0 Paired amphipathic helix repeat Baculo_PEP_C PF04513.12 EGC35241.1 - 1 9.4 26.8 0.5 10.4 0.1 5.5 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF4337 PF14235.6 EGC35241.1 - 2.8 8.0 5.5 1.5 8.9 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DUF4407 PF14362.6 EGC35241.1 - 4.4 6.6 14.4 19 4.5 0.0 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) HATPase_c PF02518.26 EGC35242.1 - 1.9e-51 173.3 0.5 3.6e-24 85.4 0.1 3.0 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC35242.1 - 5.1e-40 136.1 0.2 7.7e-25 87.2 0.1 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.25 EGC35242.1 - 9.5e-32 108.8 5.7 5.8e-17 61.5 0.3 3.6 4 0 0 4 4 4 2 His Kinase A (phospho-acceptor) domain PAS_4 PF08448.10 EGC35242.1 - 0.00013 22.2 0.0 0.00028 21.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGC35242.1 - 0.00028 21.1 1.6 0.00092 19.4 0.0 2.9 3 0 0 3 3 3 1 PAS domain Macoilin PF09726.9 EGC35242.1 - 0.78 8.2 47.3 0.024 13.2 8.6 2.4 2 0 0 2 2 2 0 Macoilin family DnaJ_C PF01556.18 EGC35243.1 - 5.4e-36 123.9 1.1 6.5e-36 123.6 1.1 1.1 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGC35243.1 - 6.1e-14 52.1 21.2 1e-13 51.4 21.2 1.4 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGC35243.1 - 2.3e-05 24.3 11.5 0.0016 18.3 2.2 2.4 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGC35243.1 - 8.2e-05 22.6 8.4 0.024 14.6 2.8 2.2 2 0 0 2 2 2 2 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EGC35243.1 - 0.41 10.3 7.7 0.41 10.3 1.4 2.2 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 DZR PF12773.7 EGC35243.1 - 1.5 9.0 12.3 4 7.6 3.6 2.2 1 1 1 2 2 2 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGC35243.1 - 1.7 9.0 7.7 3.2 8.1 0.1 3.8 3 1 1 4 4 4 0 zinc-ribbon zf-C3HC4_3 PF13920.6 EGC35243.1 - 3 7.8 8.3 0.34 10.8 1.4 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC35243.1 - 3.5 7.8 10.7 0.46 10.7 2.2 2.2 1 1 1 2 2 2 0 zinc RING finger of MSL2 DUF5351 PF17302.2 EGC35243.1 - 7.2 6.9 24.6 1.3 9.3 0.7 4.4 4 0 0 4 4 4 0 Family of unknown function (DUF5351) RhoGEF PF00621.20 EGC35244.1 - 8.8e-48 162.9 0.7 8.8e-48 162.9 0.7 1.8 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGC35244.1 - 1.8e-19 69.7 6.0 1.8e-19 69.7 6.0 2.2 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 EGC35244.1 - 1.4e-05 25.5 0.5 5.2e-05 23.7 0.0 2.2 2 1 1 3 3 3 1 PH domain FYVE_2 PF02318.16 EGC35244.1 - 0.00029 21.0 4.9 0.00029 21.0 4.9 2.7 3 0 0 3 3 3 1 FYVE-type zinc finger PEP-utilisers_N PF05524.13 EGC35244.1 - 0.0026 17.9 0.0 0.0051 17.0 0.0 1.4 1 0 0 1 1 1 1 PEP-utilising enzyme, N-terminal PH_13 PF16652.5 EGC35244.1 - 0.036 13.9 5.2 0.17 11.7 0.1 2.9 3 1 0 3 3 3 0 Pleckstrin homology domain zf-MYND PF01753.18 EGC35245.1 - 5.3e-09 36.0 12.6 9.5e-09 35.2 12.6 1.4 1 0 0 1 1 1 1 MYND finger zf-C2HC_2 PF13913.6 EGC35245.1 - 1.6 8.7 8.9 21 5.2 0.4 3.6 3 0 0 3 3 3 0 zinc-finger of a C2HC-type zf_UBZ PF18439.1 EGC35245.1 - 3.4 7.3 6.9 1.7 8.3 0.2 2.4 1 1 1 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-C6H2 PF15801.5 EGC35245.1 - 5.1 7.5 13.7 39 4.7 13.7 2.3 1 1 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding 4F5 PF04419.14 EGC35246.1 - 1.5 9.8 29.4 1.6 9.7 18.5 3.4 2 1 0 2 2 2 0 4F5 protein family SAGA-Tad1 PF12767.7 EGC35247.1 - 0.015 15.0 2.3 0.024 14.4 2.3 1.3 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF3349 PF11829.8 EGC35247.1 - 0.046 14.5 0.0 0.12 13.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3349) Mucin PF01456.17 EGC35247.1 - 2.4 8.1 19.3 4.3 7.3 19.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.12 EGC35247.1 - 3.5 5.5 9.5 4.9 5.0 9.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein B277 PF17623.2 EGC35247.1 - 4.3 6.3 8.3 7.4 5.6 8.3 1.3 1 0 0 1 1 1 0 Domain of unknown function zf-RING_2 PF13639.6 EGC35248.1 - 9.8e-09 35.4 14.7 1.7e-08 34.6 14.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC35248.1 - 1.3e-07 31.3 13.6 2.3e-07 30.5 13.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC35248.1 - 1.5e-06 28.0 12.1 2.3e-06 27.4 12.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35248.1 - 4.3e-06 26.5 15.8 8.8e-06 25.5 15.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC35248.1 - 4.5e-06 26.9 10.9 9e-06 25.9 10.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC35248.1 - 0.00048 20.1 10.6 0.0051 16.8 6.8 2.5 2 0 0 2 2 2 1 RING-type zinc-finger zf-Nse PF11789.8 EGC35248.1 - 0.00052 19.8 9.9 0.0014 18.4 9.9 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Prok-RING_4 PF14447.6 EGC35248.1 - 0.00063 19.6 11.0 0.0014 18.4 11.0 1.6 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 DUF393 PF04134.12 EGC35248.1 - 0.0051 18.1 0.3 0.011 17.1 0.0 1.8 2 0 0 2 2 1 1 Protein of unknown function, DUF393 zf-RING_5 PF14634.6 EGC35248.1 - 0.0055 16.6 14.3 0.016 15.1 14.3 1.8 1 1 1 2 2 2 1 zinc-RING finger domain Zn_ribbon_17 PF17120.5 EGC35248.1 - 0.0098 15.5 9.1 0.016 14.8 9.1 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 EGC35248.1 - 0.011 15.9 6.7 0.027 14.6 6.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-MIZ PF02891.20 EGC35248.1 - 0.039 13.7 17.4 0.078 12.7 13.9 2.6 2 1 0 2 2 2 0 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.6 EGC35248.1 - 0.048 13.8 13.6 0.26 11.5 13.8 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC35248.1 - 0.073 13.1 3.9 0.13 12.3 3.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.6 EGC35248.1 - 0.15 12.0 5.3 0.29 11.0 5.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein PBP1_TM PF14812.6 EGC35248.1 - 5.2 7.5 8.0 9.2 6.7 8.0 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FNIP PF05725.12 EGC35249.1 - 2e-108 354.3 65.7 2.1e-16 59.8 3.1 8.7 2 2 5 10 10 10 10 FNIP Repeat LRR_1 PF00560.33 EGC35249.1 - 1.1 10.1 22.1 5.8 7.9 0.3 8.2 6 3 2 8 8 8 0 Leucine Rich Repeat Strep_his_triad PF04270.13 EGC35250.1 - 0.026 14.5 0.2 0.039 13.9 0.2 1.3 1 0 0 1 1 1 0 Streptococcal histidine triad protein OTU PF02338.19 EGC35251.1 - 2.3e-11 44.3 0.1 4.7e-11 43.3 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF2457 PF10446.9 EGC35251.1 - 0.00058 19.1 4.4 0.00077 18.7 4.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) TFIIA PF03153.13 EGC35251.1 - 0.52 10.3 12.4 0.67 9.9 12.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGC35251.1 - 0.84 8.2 4.9 0.86 8.2 4.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HEPN_Swt1 PF18731.1 EGC35253.1 - 2e-10 41.0 0.1 3.1e-10 40.4 0.1 1.3 1 0 0 1 1 1 1 Swt1-like HEPN CelTOS PF18659.1 EGC35253.1 - 0.0032 17.9 1.8 0.0053 17.2 1.8 1.3 1 0 0 1 1 1 1 Cell-traversal protein for ookinetes and sporozoites COesterase PF00135.28 EGC35253.1 - 0.036 12.9 0.5 0.044 12.6 0.5 1.0 1 0 0 1 1 1 0 Carboxylesterase family Antimicrobial_7 PF08102.11 EGC35253.1 - 0.037 14.2 0.1 0.096 12.9 0.1 1.7 1 0 0 1 1 1 0 Scorpion antimicrobial peptide RRM_1 PF00076.22 EGC35254.1 - 2.2e-21 75.4 6.5 7.8e-14 51.2 0.6 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC35254.1 - 0.033 14.3 0.1 0.13 12.4 0.1 2.1 1 0 0 1 1 1 0 RNA recognition motif Spt5_N PF11942.8 EGC35254.1 - 4.9 8.2 17.2 0.057 14.4 7.0 2.9 3 1 0 3 3 3 0 Spt5 transcription elongation factor, acidic N-terminal DNA_ligase_aden PF01653.18 EGC35255.1 - 4.3e-64 216.6 10.2 9.3e-40 136.7 7.4 3.2 1 1 1 2 2 2 2 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.16 EGC35255.1 - 1.2e-24 86.0 2.1 1.2e-24 86.0 2.1 2.1 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.7 EGC35255.1 - 2.2e-09 37.3 0.0 6.2e-09 35.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif 5_3_exonuc PF01367.20 EGC35255.1 - 0.071 13.7 1.4 2 9.1 0.0 3.2 2 1 0 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold RabGAP-TBC PF00566.18 EGC35256.1 - 9.2e-52 175.8 0.3 9.2e-52 175.8 0.3 3.8 3 2 1 4 4 4 1 Rab-GTPase-TBC domain Ank_2 PF12796.7 EGC35256.1 - 4.7e-14 52.7 4.5 5.5e-11 42.9 0.1 2.8 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGC35256.1 - 9.7e-11 41.6 3.9 0.049 14.1 0.1 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_3 PF13606.6 EGC35256.1 - 1.8e-10 40.1 0.6 0.071 13.7 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGC35256.1 - 1.3e-09 38.2 0.9 0.0057 16.9 0.0 4.2 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC35256.1 - 1.9e-08 34.7 0.5 3.1e-05 24.4 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Oxidored_FMN PF00724.20 EGC35256.1 - 0.0052 16.1 2.5 0.0097 15.2 2.5 1.4 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M8 PF01457.16 EGC35257.1 - 1.8e-69 234.8 3.6 2.6e-69 234.3 3.6 1.1 1 0 0 1 1 1 1 Leishmanolysin Meleagrin PF08189.11 EGC35257.1 - 0.047 13.4 1.8 0.16 11.7 1.8 1.9 1 0 0 1 1 1 0 Meleagrin/Cygnin family Pro_isomerase PF00160.21 EGC35258.1 - 8.4e-41 139.9 0.0 1e-40 139.6 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Meth_synt_2 PF01717.18 EGC35259.1 - 8.6e-11 41.7 0.0 6.4e-10 38.8 0.0 2.1 1 1 1 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Terpene_synth_C PF03936.16 EGC35260.1 - 0.013 14.8 0.0 0.02 14.2 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase family, metal binding domain RNA_lig_T4_1 PF09511.10 EGC35263.1 - 2.9e-34 118.8 0.3 2.9e-34 118.8 0.3 1.5 2 0 0 2 2 2 1 RNA ligase DZR PF12773.7 EGC35264.1 - 0.29 11.2 1.2 0.67 10.0 1.2 1.6 1 0 0 1 1 1 0 Double zinc ribbon HAD_2 PF13419.6 EGC35265.1 - 8.9e-12 45.4 3.7 3.2e-05 24.1 1.7 2.9 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGC35265.1 - 8.7e-09 36.0 0.0 6.2e-07 29.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EGC35265.1 - 3.6e-07 30.0 0.1 8e-07 28.9 0.0 1.6 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.6 EGC35265.1 - 0.00027 20.9 0.0 0.00046 20.2 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Imm41 PF15592.6 EGC35265.1 - 0.01 16.2 0.3 0.028 14.7 0.3 1.8 1 0 0 1 1 1 1 Immunity protein 41 TM2 PF05154.16 EGC35266.1 - 2e-19 69.7 15.7 2.6e-19 69.3 15.7 1.1 1 0 0 1 1 1 1 TM2 domain Snf7 PF03357.21 EGC35267.1 - 2e-29 102.4 26.7 2.2e-29 102.2 26.7 1.0 1 0 0 1 1 1 1 Snf7 C9orf72-like PF15019.6 EGC35267.1 - 0.13 11.8 4.1 0.17 11.4 4.1 1.2 1 0 0 1 1 1 0 C9orf72-like protein family Glyco_hydro_65m PF03632.15 EGC35268.1 - 1.6e-49 168.8 3.8 8.7e-42 143.3 0.4 2.5 2 1 1 3 3 3 2 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.9 EGC35268.1 - 7.5e-14 51.0 0.0 2.1e-10 39.6 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) Glyco_hydro_65N PF03636.15 EGC35268.1 - 0.02 14.5 3.6 0.087 12.4 3.5 1.9 1 1 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain FNIP PF05725.12 EGC35269.1 - 7.1e-45 150.9 64.7 4.6e-11 42.7 3.8 9.5 9 1 0 10 10 10 8 FNIP Repeat HTH_37 PF13744.6 EGC35273.1 - 0.1 12.5 0.1 0.4 10.7 0.1 2.0 1 0 0 1 1 1 0 Helix-turn-helix domain Pyr_redox_2 PF07992.14 EGC35274.1 - 2e-37 129.0 0.0 2.5e-37 128.7 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC35274.1 - 7.7e-19 68.0 1.6 3.4e-13 50.0 0.2 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC35274.1 - 1.2e-12 47.7 0.2 2.4e-08 33.6 0.1 2.2 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGC35274.1 - 7.6e-11 42.2 0.0 0.011 15.4 0.0 3.3 3 0 0 3 3 3 3 FAD dependent oxidoreductase DUF1188 PF06690.11 EGC35274.1 - 2.4e-07 30.6 0.6 0.00011 21.8 0.2 2.2 2 0 0 2 2 2 2 Protein of unknown function (DUF1188) NAD_binding_8 PF13450.6 EGC35274.1 - 7.4e-07 29.3 0.1 0.017 15.3 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.6 EGC35274.1 - 1.8e-06 27.4 0.2 0.0055 15.9 0.1 2.3 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) TrkA_N PF02254.18 EGC35274.1 - 1.7e-05 25.0 1.0 0.08 13.2 0.1 2.7 2 1 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.14 EGC35274.1 - 1.9e-05 23.7 0.1 0.019 13.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase Sacchrp_dh_NADP PF03435.18 EGC35274.1 - 3.9e-05 23.9 0.2 0.3 11.4 0.1 2.5 2 0 0 2 2 2 2 Saccharopine dehydrogenase NADP binding domain Lycopene_cycl PF05834.12 EGC35274.1 - 0.00016 20.9 0.0 0.36 9.8 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein NAD_binding_7 PF13241.6 EGC35274.1 - 0.00019 21.8 0.2 0.23 11.9 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.6 EGC35274.1 - 0.0007 19.6 3.4 3.7 7.5 0.0 3.5 2 2 1 3 3 3 1 FAD-NAD(P)-binding HI0933_like PF03486.14 EGC35274.1 - 0.0025 16.6 0.7 0.36 9.5 0.0 2.8 3 1 0 3 3 3 1 HI0933-like protein ApbA PF02558.16 EGC35274.1 - 0.0032 17.1 0.0 2.1 8.0 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA AlaDh_PNT_C PF01262.21 EGC35274.1 - 0.0032 16.8 0.1 0.96 8.7 0.0 2.4 3 0 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.18 EGC35274.1 - 0.0063 16.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EGC35274.1 - 0.0066 15.7 0.0 2.2 7.4 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Spermine_synth PF01564.17 EGC35274.1 - 0.026 13.9 0.2 1 8.7 0.0 2.4 2 0 0 2 2 2 0 Spermine/spermidine synthase domain Shikimate_DH PF01488.20 EGC35274.1 - 0.028 14.5 0.1 4.3 7.4 0.1 2.4 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF2556 PF10831.8 EGC35275.1 - 0.087 12.8 0.9 0.17 11.8 0.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2556) GPI2 PF06432.11 EGC35276.1 - 1.8e-92 309.8 16.4 2e-92 309.6 16.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase Maf1 PF09174.10 EGC35276.1 - 0.022 14.9 1.1 1.2 9.3 0.1 2.1 2 0 0 2 2 2 0 Maf1 regulator DUF5313 PF17240.2 EGC35276.1 - 0.23 11.9 1.2 0.61 10.5 1.2 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5313) Pentapeptide PF00805.22 EGC35277.1 - 4.9e-20 70.8 25.2 3.4e-07 29.8 4.5 5.6 3 1 3 6 6 6 6 Pentapeptide repeats (8 copies) BTB_2 PF02214.22 EGC35277.1 - 4.6e-18 65.3 0.0 1.2e-17 64.0 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_4 PF13599.6 EGC35277.1 - 5.7e-16 58.5 20.8 3.5e-09 36.7 4.7 4.6 2 1 2 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGC35277.1 - 6.8e-09 35.7 26.5 7.6e-05 22.8 11.3 5.4 3 2 1 4 4 4 2 Pentapeptide repeats (9 copies) CorA PF01544.18 EGC35278.1 - 3.4e-33 115.2 5.9 3.4e-33 115.2 5.9 2.2 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein CcmB PF03379.13 EGC35278.1 - 0.13 11.7 0.0 0.23 11.0 0.0 1.3 1 0 0 1 1 1 0 CcmB protein DUF5392 PF17370.2 EGC35278.1 - 0.25 11.4 4.2 2.7 8.1 0.3 3.0 1 1 1 2 2 2 0 Family of unknown function (DUF5392) SpoIIM PF01944.17 EGC35278.1 - 8 6.5 7.7 6.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Stage II sporulation protein M VCPO_N PF17897.1 EGC35279.1 - 0.0011 18.8 0.2 0.0018 18.1 0.2 1.3 1 0 0 1 1 1 1 Vanadium chloroperoxidase N-terminal domain PAP2 PF01569.21 EGC35279.1 - 0.0068 16.2 0.0 0.014 15.1 0.0 1.6 1 0 0 1 1 1 1 PAP2 superfamily CBS PF00571.28 EGC35280.1 - 1.1e-30 105.8 6.3 2.3e-09 37.6 0.1 4.2 4 0 0 4 4 4 4 CBS domain SporV_AA PF12164.8 EGC35280.1 - 0.046 14.1 2.9 0.3 11.5 0.6 2.6 2 0 0 2 2 2 0 Stage V sporulation protein AA Med9 PF07544.13 EGC35281.1 - 1.1e-05 25.4 4.4 1.1e-05 25.4 4.4 2.7 2 1 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 UPA_2 PF17809.1 EGC35281.1 - 0.057 13.2 2.1 0.09 12.6 0.0 2.1 1 1 1 2 2 2 0 UPA domain MID_MedPIWI PF18296.1 EGC35281.1 - 0.28 10.9 8.4 0.37 10.5 8.4 1.2 1 0 0 1 1 1 0 MID domain of medPIWI Zip PF02535.22 EGC35281.1 - 0.58 9.3 7.9 0.68 9.1 7.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ALMT PF11744.8 EGC35281.1 - 1.2 7.8 13.3 1.4 7.7 13.3 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CSG2 PF16965.5 EGC35281.1 - 1.3 7.8 5.5 1.6 7.6 5.5 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator SID-1_RNA_chan PF13965.6 EGC35281.1 - 1.9 6.8 4.6 1.9 6.8 4.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Presenilin PF01080.17 EGC35281.1 - 8.1 5.1 13.4 9 4.9 13.4 1.2 1 0 0 1 1 1 0 Presenilin ABC2_membrane_3 PF12698.7 EGC35283.1 - 1.9e-36 125.9 26.1 2.6e-36 125.4 26.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.24 EGC35283.1 - 4.5e-32 111.2 27.1 1.1e-31 110.0 15.2 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC35283.1 - 7.8e-25 88.0 0.0 1.6e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_2 PF12679.7 EGC35283.1 - 6.8e-17 61.7 8.1 9.7e-17 61.2 8.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGC35283.1 - 5.7e-09 36.2 1.0 0.00073 19.4 0.0 2.4 1 1 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC35283.1 - 0.0026 17.5 0.1 0.0062 16.3 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC35283.1 - 0.0069 16.8 0.1 0.019 15.4 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.6 EGC35283.1 - 0.04 14.4 0.8 0.1 13.1 0.8 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGC35283.1 - 0.042 13.3 0.2 2 7.8 0.1 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGC35283.1 - 0.045 13.5 0.0 0.077 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC35283.1 - 0.048 13.9 0.4 0.18 12.1 0.2 2.1 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGC35283.1 - 0.069 13.1 1.4 0.073 13.0 0.2 1.6 2 0 0 2 2 2 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGC35283.1 - 0.09 12.1 0.1 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 FtsK/SpoIIIE family Abhydrolase_1 PF00561.20 EGC35284.1 - 3.8e-16 59.5 1.5 2.1e-14 53.8 0.3 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC35284.1 - 2.2e-15 56.6 0.0 3.6e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC35284.1 - 2.3e-11 44.7 0.0 3.9e-11 44.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.25 EGC35284.1 - 0.00054 19.8 0.1 0.0015 18.4 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 3) DUF1057 PF06342.12 EGC35284.1 - 0.00061 18.9 0.5 0.0017 17.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.13 EGC35284.1 - 0.0044 16.7 0.0 1.6 8.3 0.0 2.5 2 0 0 2 2 2 2 Serine hydrolase (FSH1) POTRA_1 PF08478.10 EGC35284.1 - 0.0068 16.7 0.4 0.31 11.4 0.1 2.6 2 0 0 2 2 2 1 POTRA domain, FtsQ-type Lipase PF00151.19 EGC35284.1 - 0.018 14.4 0.0 0.036 13.4 0.0 1.6 1 1 0 1 1 1 0 Lipase Esterase PF00756.20 EGC35284.1 - 0.019 14.6 0.1 0.048 13.3 0.1 2.0 1 1 0 1 1 1 0 Putative esterase Abhydrolase_5 PF12695.7 EGC35284.1 - 0.047 13.4 0.1 0.18 11.6 0.0 1.9 2 1 0 2 2 2 0 Alpha/beta hydrolase family WD40 PF00400.32 EGC35285.1 - 2.8e-67 221.0 38.7 1.9e-06 28.5 0.2 13.4 13 0 0 13 13 13 11 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35285.1 - 2.6e-23 82.1 2.5 1.7e-05 25.0 0.0 7.9 3 2 4 8 8 8 5 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC35285.1 - 1.6e-11 43.8 6.8 0.024 13.6 0.0 6.9 2 2 3 7 7 7 5 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC35285.1 - 8.9e-09 34.5 2.2 0.0017 17.1 0.6 3.6 4 0 0 4 4 4 3 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.16 EGC35285.1 - 8.4e-07 27.8 0.1 0.022 13.3 0.1 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain WD40_like PF17005.5 EGC35285.1 - 8.9e-06 25.2 14.8 0.0029 17.0 6.0 4.2 4 1 0 4 4 4 2 WD40-like domain PD40 PF07676.12 EGC35285.1 - 0.037 14.0 0.1 0.61 10.1 0.0 3.2 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat CbtA_toxin PF06755.12 EGC35286.1 - 0.0026 17.7 0.0 0.0067 16.4 0.0 1.7 1 0 0 1 1 1 1 CbtA_toxin of type IV toxin-antitoxin system RRM_1 PF00076.22 EGC35288.1 - 1.7e-17 63.0 0.0 5.8e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.22 EGC35288.1 - 9.1e-10 38.4 0.0 1.8e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.7 EGC35288.1 - 1.2e-06 28.4 0.5 1.2e-06 28.4 0.5 3.1 3 0 0 3 3 3 1 SUZ-C motif Limkain-b1 PF11608.8 EGC35288.1 - 0.00083 19.4 0.2 0.67 10.1 0.1 2.9 2 1 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.6 EGC35288.1 - 0.0098 15.9 0.0 0.023 14.7 0.0 1.6 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3535 PF12054.8 EGC35289.1 - 4e-81 273.5 7.5 4e-81 273.5 7.5 3.2 4 0 0 4 4 4 1 Domain of unknown function (DUF3535) SNF2_N PF00176.23 EGC35289.1 - 9.1e-63 212.1 0.0 2.5e-62 210.6 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC35289.1 - 7.1e-18 65.0 0.1 7.1e-18 65.0 0.1 4.0 5 0 0 5 5 5 1 Helicase conserved C-terminal domain HEAT PF02985.22 EGC35289.1 - 2.2e-14 52.3 0.8 0.076 13.3 0.0 8.4 9 0 0 9 9 9 3 HEAT repeat Vac14_Fab1_bd PF12755.7 EGC35289.1 - 2.1e-08 34.6 0.2 3e-05 24.5 0.0 3.6 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.6 EGC35289.1 - 1.9e-06 28.2 4.2 0.0011 19.4 0.0 5.3 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGC35289.1 - 1.2e-05 25.6 0.4 0.43 11.0 0.0 4.6 4 0 0 4 4 4 2 HEAT repeats Cnd1 PF12717.7 EGC35289.1 - 0.0021 18.2 3.9 2.9 7.9 0.0 5.9 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1 DUF3385 PF11865.8 EGC35289.1 - 1.3 8.9 9.5 3.8 7.4 0.0 4.6 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Synaptobrevin PF00957.21 EGC35290.1 - 4.9e-26 90.3 6.9 7.3e-26 89.8 6.9 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGC35290.1 - 1.6e-15 56.9 0.1 2.7e-15 56.1 0.1 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain RIFIN PF02009.16 EGC35290.1 - 0.00075 19.5 0.5 0.001 19.1 0.5 1.2 1 0 0 1 1 1 1 Rifin CD34_antigen PF06365.12 EGC35290.1 - 0.11 12.0 0.3 0.16 11.5 0.3 1.1 1 0 0 1 1 1 0 CD34/Podocalyxin family Dimer_Tnp_hAT PF05699.14 EGC35293.1 - 8.3e-10 38.3 0.1 9.7e-10 38.1 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF5126 PF17166.4 EGC35293.1 - 0.09 12.7 0.1 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF5126) ATG101 PF07855.12 EGC35294.1 - 1.9e-34 118.9 1.5 2.3e-34 118.6 1.5 1.1 1 0 0 1 1 1 1 Autophagy-related protein 101 SWIRM PF04433.17 EGC35295.1 - 1.3e-22 79.9 0.4 5.2e-22 78.0 0.4 2.1 1 0 0 1 1 1 1 SWIRM domain Myb_DNA-binding PF00249.31 EGC35295.1 - 0.024 14.8 0.0 0.068 13.4 0.0 1.8 1 0 0 1 1 1 0 Myb-like DNA-binding domain zf-C3HC4_3 PF13920.6 EGC35297.1 - 3.2e-11 42.9 12.2 5.4e-11 42.2 12.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC35297.1 - 2.7e-05 23.9 13.0 5.6e-05 22.9 13.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC35297.1 - 0.0084 16.0 14.0 0.017 15.1 14.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain PRKCSH_1 PF13015.6 EGC35298.1 - 0.047 13.4 10.3 0.033 13.9 1.1 3.1 3 0 0 3 3 3 0 Glucosidase II beta subunit-like protein WD40 PF00400.32 EGC35300.1 - 1.1e-39 133.6 23.9 6.5e-07 30.0 0.0 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.11 EGC35300.1 - 5.8e-13 48.1 3.9 5.8e-13 48.1 3.9 2.0 2 0 0 2 2 2 1 pre-mRNA processing factor 4 (PRP4) like ANAPC4_WD40 PF12894.7 EGC35300.1 - 1e-10 41.7 2.2 0.0011 19.2 0.0 5.2 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC35300.1 - 0.00035 19.6 2.4 0.58 9.1 0.0 3.8 1 1 3 4 4 4 2 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGC35300.1 - 0.017 14.5 0.0 0.61 9.4 0.0 2.4 1 1 1 2 2 2 0 WD40-like domain Herpes_UL37_1 PF03970.13 EGC35300.1 - 0.15 11.3 0.0 0.24 10.6 0.0 1.3 1 0 0 1 1 1 0 Herpesvirus UL37 tegument protein LRR_4 PF12799.7 EGC35301.1 - 2.6e-16 59.5 89.9 0.012 16.1 6.9 16.7 6 3 10 17 17 17 13 Leucine Rich repeats (2 copies) YobH PF13996.6 EGC35301.1 - 0.27 11.3 3.6 1.2 9.3 0.0 3.6 4 0 0 4 4 4 0 YobH-like protein LRR_6 PF13516.6 EGC35301.1 - 1.3 9.3 65.3 0.74 10.0 0.5 17.9 20 0 0 20 20 20 0 Leucine Rich repeat FNIP PF05725.12 EGC35302.1 - 1.7e-65 216.9 47.6 2.8e-13 49.8 0.1 8.6 6 2 2 8 8 8 7 FNIP Repeat APG6 PF04111.12 EGC35303.1 - 4.2e-72 241.9 0.2 4.2e-72 241.9 0.2 1.8 2 0 0 2 2 2 1 Apg6 BARA domain APG6_N PF17675.1 EGC35303.1 - 1.7e-20 73.9 14.8 1.7e-20 73.9 14.8 2.4 2 0 0 2 2 2 1 Apg6 coiled-coil region DUF2730 PF10805.8 EGC35303.1 - 3.2 7.9 6.0 8.6 6.5 0.5 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) AA_kinase PF00696.28 EGC35304.1 - 9.4e-44 149.8 0.1 1.2e-43 149.5 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase_Tyr PF07714.17 EGC35305.1 - 3.2e-52 177.4 1.3 5.1e-52 176.7 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35305.1 - 1.1e-45 156.1 0.0 1.1e-45 156.1 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.23 EGC35305.1 - 0.035 14.0 0.1 0.035 14.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family C1_1 PF00130.22 EGC35305.1 - 0.091 12.7 17.6 0.014 15.2 13.2 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) F-box PF00646.33 EGC35305.1 - 0.12 12.3 0.1 0.4 10.6 0.1 1.9 1 0 0 1 1 1 0 F-box domain LAGLIDADG_1 PF00961.19 EGC35306.1 - 1.1 10.2 13.6 0.11 13.4 4.4 3.0 2 1 1 3 3 3 0 LAGLIDADG endonuclease Toprim_2 PF13155.6 EGC35307.1 - 1.4e-05 25.5 0.0 3e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 Toprim-like Toprim_4 PF13662.6 EGC35307.1 - 0.0045 17.4 0.0 0.16 12.4 0.0 2.7 2 1 0 2 2 2 1 Toprim domain ATPase PF06745.13 EGC35307.1 - 0.013 14.9 0.3 0.025 13.9 0.3 1.4 1 0 0 1 1 1 0 KaiC tRNA-synt_2b PF00587.25 EGC35308.1 - 2.8e-35 121.9 0.0 6.9e-35 120.6 0.0 1.6 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGC35308.1 - 9e-22 77.0 1.9 1.7e-21 76.1 1.9 1.5 1 0 0 1 1 1 1 Anticodon binding domain tRNA_SAD PF07973.14 EGC35308.1 - 8.3e-13 48.2 0.0 1.8e-12 47.1 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain TGS PF02824.21 EGC35308.1 - 9.3e-13 48.0 0.1 2.1e-12 46.9 0.1 1.7 1 0 0 1 1 1 1 TGS domain DUF4897 PF16238.5 EGC35308.1 - 0.094 12.6 0.2 4.8 7.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4897) Lipase3_N PF03893.16 EGC35308.1 - 0.17 11.9 0.0 0.7 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipase 3 N-terminal region DSPc PF00782.20 EGC35309.1 - 6.9e-25 87.4 3.1 8.3e-25 87.1 0.0 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.22 EGC35309.1 - 6.9e-08 32.3 0.3 0.26 11.2 0.0 3.7 3 0 0 3 3 3 3 Gelsolin repeat CDKN3 PF05706.12 EGC35309.1 - 0.047 13.4 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Pre-PUA PF17832.1 EGC35310.1 - 1.3e-21 77.1 1.7 3.8e-21 75.6 1.7 1.9 1 0 0 1 1 1 1 Pre-PUA-like domain SUI1 PF01253.22 EGC35310.1 - 3.1e-12 46.9 0.2 8.8e-12 45.4 0.2 1.8 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mucin PF01456.17 EGC35310.1 - 9.5e-05 22.4 4.9 0.00016 21.7 4.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SWIB PF02201.18 EGC35310.1 - 0.0045 16.9 1.3 0.032 14.1 0.3 2.6 2 0 0 2 2 2 1 SWIB/MDM2 domain DUF3439 PF11921.8 EGC35310.1 - 0.031 14.2 7.0 0.069 13.1 7.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AJAP1_PANP_C PF15298.6 EGC35310.1 - 0.58 10.3 8.9 3.7 7.7 8.8 2.1 2 0 0 2 2 2 0 AJAP1/PANP C-terminus DUF2052 PF09747.9 EGC35310.1 - 0.59 10.2 11.0 1 9.5 4.2 2.3 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) HTH_56 PF18662.1 EGC35310.1 - 1.4 9.0 9.3 1.4 9.0 0.4 3.5 4 1 0 4 4 4 0 Cch helix turn helix domain SSP160 PF06933.11 EGC35310.1 - 4.2 5.4 11.6 5.9 5.0 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SMP PF04927.12 EGC35311.1 - 7.6e-07 29.5 2.7 8.3e-07 29.4 2.7 1.1 1 0 0 1 1 1 1 Seed maturation protein Ifi-6-16 PF06140.13 EGC35311.1 - 3.7e-06 26.8 7.8 4.3e-06 26.5 7.8 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family Macoilin PF09726.9 EGC35312.1 - 0.18 10.4 21.0 0.2 10.2 21.0 1.0 1 0 0 1 1 1 0 Macoilin family TCP PF03634.13 EGC35312.1 - 1.1 9.8 15.4 8 7.0 9.1 2.1 2 0 0 2 2 2 0 TCP family transcription factor Corona_nucleoca PF00937.18 EGC35312.1 - 5.9 5.8 17.7 2.3 7.2 0.7 2.1 2 0 0 2 2 2 0 Coronavirus nucleocapsid protein DUF4834 PF16118.5 EGC35314.1 - 0.015 16.3 0.1 0.036 15.0 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF3328 PF11807.8 EGC35314.1 - 0.081 12.7 0.1 0.11 12.3 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) CLU PF13236.6 EGC35315.1 - 4.7e-60 203.2 0.0 2.9e-59 200.6 0.0 2.4 2 0 0 2 2 2 1 Clustered mitochondria VHP PF02209.19 EGC35315.1 - 1.5e-13 50.5 2.5 1.1e-12 47.7 2.5 2.7 1 0 0 1 1 1 1 Villin headpiece domain eIF3_p135 PF12807.7 EGC35315.1 - 4e-08 33.5 0.5 4e-08 33.5 0.5 3.2 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 LRR_6 PF13516.6 EGC35315.1 - 5.8e-05 22.8 44.5 0.12 12.5 0.1 13.8 15 0 0 15 15 15 3 Leucine Rich repeat TPR_11 PF13414.6 EGC35315.1 - 0.025 14.3 0.1 0.13 12.0 0.0 2.3 2 0 0 2 2 2 0 TPR repeat DUF2655 PF10848.8 EGC35316.1 - 0.042 14.2 0.0 0.13 12.6 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2655) Ntox44 PF15607.6 EGC35317.1 - 0.16 12.3 2.0 1.3 9.4 2.0 2.0 1 1 0 1 1 1 0 Bacterial toxin 44 XRN_N PF03159.18 EGC35318.1 - 5.3e-59 199.6 0.0 6.1e-59 199.4 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus BSD PF03909.17 EGC35319.1 - 1.1e-07 31.8 0.3 1.1e-07 31.8 0.3 2.2 2 0 0 2 2 2 1 BSD domain FNIP PF05725.12 EGC35320.1 - 1.1e-151 492.8 90.9 1.5e-16 60.3 1.6 10.1 1 1 10 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.13 EGC35320.1 - 0.054 13.9 0.0 28 5.1 0.0 4.1 3 0 0 3 3 3 0 Phage minor tail protein HTH_ABP1_N PF18107.1 EGC35320.1 - 0.2 11.4 0.0 36 4.2 0.0 3.6 4 0 0 4 4 4 0 Fission yeast centromere protein N-terminal domain Nucleoporin_FG2 PF15967.5 EGC35321.1 - 0.28 9.7 1.6 0.29 9.6 1.6 1.0 1 0 0 1 1 1 0 Nucleoporin FG repeated region CAP_N PF01213.19 EGC35322.1 - 0.045 13.2 0.4 0.06 12.8 0.4 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Coiled PF05710.12 EGC35323.1 - 0.52 11.2 13.1 1.3 9.9 13.1 1.7 1 1 0 1 1 1 0 Coiled coil CAP_N PF01213.19 EGC35324.1 - 0.023 14.2 1.4 0.027 13.9 1.4 1.1 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Glyco_hydro_67N PF03648.14 EGC35324.1 - 0.1 12.9 0.0 0.18 12.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 67 N-terminus Coiled PF05710.12 EGC35325.1 - 0.061 14.2 15.8 0.1 13.4 15.8 1.4 1 1 0 1 1 1 0 Coiled coil FR47 PF08445.10 EGC35327.1 - 2.1e-11 43.6 0.0 3.6e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_1 PF00583.25 EGC35327.1 - 4.2e-06 27.0 0.0 7.6e-06 26.1 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EGC35327.1 - 4.3e-05 24.2 0.0 8.7e-05 23.2 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGC35327.1 - 0.00059 19.5 0.1 0.0017 18.0 0.0 1.7 2 0 0 2 2 2 1 GNAT acetyltransferase Acetyltransf_10 PF13673.7 EGC35327.1 - 0.0012 18.7 0.0 0.0024 17.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC35327.1 - 0.0036 16.8 0.3 0.0057 16.2 0.3 1.4 1 0 0 1 1 1 1 Putative acetyl-transferase Gly_acyl_tr_C PF08444.10 EGC35327.1 - 0.005 17.0 0.0 0.014 15.6 0.0 1.7 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.7 EGC35327.1 - 0.0068 16.8 0.0 0.012 16.0 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain BB_PF PF18063.1 EGC35330.1 - 1.1e-27 96.9 4.2 1.1e-27 96.9 4.2 1.7 2 0 0 2 2 2 1 Beta barrel Pore-forming domain TMEM51 PF15345.6 EGC35332.1 - 0.00026 20.9 0.3 0.0004 20.3 0.3 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Zip PF02535.22 EGC35332.1 - 0.16 11.1 1.5 0.21 10.7 1.5 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.13 EGC35332.1 - 0.23 10.2 5.7 0.4 9.4 5.7 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Coiled PF05710.12 EGC35333.1 - 2.5e-17 63.5 20.0 3.6e-17 63.0 20.0 1.2 1 0 0 1 1 1 1 Coiled coil Aldolase_II PF00596.21 EGC35334.1 - 9.3e-44 149.6 0.0 1.1e-43 149.3 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pmp3 PF01679.17 EGC35336.1 - 8.8e-20 70.7 12.7 9.3e-20 70.6 12.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF4191 PF13829.6 EGC35336.1 - 0.26 10.6 3.0 0.28 10.5 3.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) IATP PF04568.12 EGC35337.1 - 0.13 12.7 1.7 0.19 12.2 1.7 1.2 1 0 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ERCC4 PF02732.15 EGC35338.1 - 4.4e-28 98.5 0.7 4.4e-28 98.5 0.7 3.2 4 0 0 4 4 4 1 ERCC4 domain HHH_8 PF14716.6 EGC35338.1 - 0.00012 22.4 0.0 0.00022 21.5 0.0 1.5 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH PF00633.23 EGC35338.1 - 0.0053 16.6 0.0 0.015 15.1 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Mucin PF01456.17 EGC35338.1 - 0.96 9.4 12.4 0.12 12.3 6.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein FYVE PF01363.21 EGC35339.1 - 5.3e-17 61.7 13.1 6.8e-17 61.4 11.9 1.8 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.29 EGC35339.1 - 2.6e-07 31.1 7.2 0.00058 20.3 0.1 3.7 4 0 0 4 4 4 2 PH domain PH_3 PF14593.6 EGC35339.1 - 0.00017 21.7 4.1 0.13 12.4 0.0 3.1 3 0 0 3 3 3 2 PH domain PH_11 PF15413.6 EGC35339.1 - 0.0023 18.3 12.1 0.0061 17.0 0.1 3.8 3 1 0 3 3 3 1 Pleckstrin homology domain Med11 PF10280.9 EGC35339.1 - 0.003 18.0 0.9 0.003 18.0 0.9 2.1 2 1 0 2 2 2 1 Mediator complex protein FYVE_2 PF02318.16 EGC35339.1 - 0.006 16.8 7.6 0.016 15.4 7.6 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger IBR PF01485.21 EGC35339.1 - 0.033 14.4 6.6 0.11 12.8 6.6 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain PH_2 PF08458.10 EGC35339.1 - 0.035 14.5 0.0 0.091 13.1 0.0 1.8 1 0 0 1 1 1 0 Plant pleckstrin homology-like region TPR_MLP1_2 PF07926.12 EGC35339.1 - 0.14 12.2 3.2 0.49 10.5 3.1 1.8 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein C1_2 PF03107.16 EGC35339.1 - 0.47 10.8 7.1 1.6 9.1 7.1 1.9 1 0 0 1 1 1 0 C1 domain DUF4407 PF14362.6 EGC35339.1 - 7.7 5.8 5.5 9.6 5.5 4.0 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4407) Uso1_p115_C PF04871.13 EGC35339.1 - 8.5 6.8 8.2 0.39 11.1 1.3 2.3 2 1 1 3 3 3 0 Uso1 / p115 like vesicle tethering protein, C terminal region Voltage_CLC PF00654.20 EGC35340.1 - 3.3e-98 329.2 18.7 3.3e-98 329.2 18.7 1.9 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGC35340.1 - 6.3e-15 55.4 0.7 3.4e-07 30.6 0.1 2.5 2 0 0 2 2 2 2 CBS domain ACR_tran PF00873.19 EGC35340.1 - 0.04 11.6 2.9 0.065 10.9 2.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FNIP PF05725.12 EGC35341.1 - 5.6e-11 42.4 57.8 7.4e-05 22.8 0.4 10.2 7 3 2 9 9 9 8 FNIP Repeat adh_short PF00106.25 EGC35342.1 - 1.4e-41 142.1 0.0 2e-41 141.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC35342.1 - 2.6e-29 102.5 0.0 3.8e-29 101.9 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC35342.1 - 1.5e-09 38.0 0.0 2.2e-09 37.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC35342.1 - 6.6e-05 22.5 0.7 0.00015 21.3 0.4 1.9 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGC35342.1 - 0.00023 21.1 0.0 0.00043 20.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGC35342.1 - 0.00026 20.5 0.3 0.00051 19.5 0.2 1.6 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGC35342.1 - 0.0007 18.8 0.0 0.00095 18.3 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain DUF1776 PF08643.10 EGC35342.1 - 0.0025 17.2 0.1 0.0033 16.8 0.1 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGC35342.1 - 0.019 14.1 0.0 0.029 13.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGC35342.1 - 0.019 14.0 0.2 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Peripla_BP_4 PF13407.6 EGC35342.1 - 0.021 14.4 0.0 0.034 13.7 0.0 1.4 1 0 0 1 1 1 0 Periplasmic binding protein domain TrkA_N PF02254.18 EGC35342.1 - 0.053 13.8 0.1 0.11 12.8 0.1 1.5 1 0 0 1 1 1 0 TrkA-N domain Glyco_transf_4 PF13439.6 EGC35342.1 - 0.095 12.7 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyltransferase Family 4 Transglut_core PF01841.19 EGC35344.1 - 1.8e-13 50.9 0.0 5.4e-13 49.4 0.0 1.7 2 0 0 2 2 2 1 Transglutaminase-like superfamily adh_short PF00106.25 EGC35345.1 - 3.3e-28 98.5 0.6 1.1e-27 96.8 0.6 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC35345.1 - 2.8e-15 56.5 0.0 8.3e-15 55.0 0.0 1.7 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC35345.1 - 4.9e-07 29.8 0.0 9.9e-07 28.8 0.0 1.6 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC35345.1 - 0.0023 17.4 4.8 0.0058 16.0 4.8 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Ribosomal_L31e PF01198.19 EGC35345.1 - 0.028 14.7 2.3 3.5 7.9 0.1 2.9 3 0 0 3 3 3 0 Ribosomal protein L31e QRPTase_C PF01729.19 EGC35345.1 - 0.079 12.7 0.2 0.18 11.6 0.2 1.5 1 0 0 1 1 1 0 Quinolinate phosphoribosyl transferase, C-terminal domain Epimerase PF01370.21 EGC35345.1 - 0.091 12.2 0.1 0.33 10.4 0.0 1.8 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Adhesin_E PF16747.5 EGC35346.1 - 0.018 15.1 0.1 0.054 13.5 0.1 1.8 1 0 0 1 1 1 0 Surface-adhesin protein E MSC PF09402.10 EGC35347.1 - 1.2 8.5 2.6 5.2 6.4 1.7 2.2 2 0 0 2 2 2 0 Man1-Src1p-C-terminal domain FNIP PF05725.12 EGC35348.1 - 8.7e-57 189.1 43.0 4e-10 39.7 4.2 9.6 5 2 3 9 9 9 9 FNIP Repeat ACP53EA PF06313.11 EGC35348.1 - 0.077 13.2 0.0 0.36 11.1 0.0 2.1 2 0 0 2 2 2 0 Drosophila ACP53EA protein LIM PF00412.22 EGC35349.1 - 6.8e-30 103.1 26.6 1.6e-12 47.5 2.2 3.1 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.22 EGC35349.1 - 0.042 13.7 28.0 0.1 12.5 1.7 5.1 1 1 3 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1383 PF07134.11 EGC35349.1 - 0.16 11.1 0.2 1.8 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1383) zf_UBZ PF18439.1 EGC35349.1 - 1.6 8.4 0.1 1.6 8.4 0.1 5.8 6 0 0 6 6 6 0 Ubiquitin-Binding Zinc Finger CDC50 PF03381.15 EGC35350.1 - 5.1e-90 301.8 0.2 9.4e-90 300.9 0.0 1.5 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CrgA PF06781.12 EGC35350.1 - 0.11 12.6 0.1 16 5.6 0.0 2.3 2 0 0 2 2 2 0 Cell division protein CrgA DUF202 PF02656.15 EGC35350.1 - 0.51 10.8 1.9 10 6.7 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF202) SieB PF14163.6 EGC35350.1 - 0.51 9.8 3.6 1.1 8.8 0.2 2.3 2 0 0 2 2 2 0 Super-infection exclusion protein B DUF3185 PF11381.8 EGC35350.1 - 1.5 8.9 4.5 9 6.4 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Acyl-CoA_dh_M PF02770.19 EGC35351.1 - 3.6e-15 55.9 0.0 1.4e-14 54.0 0.0 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC35351.1 - 1.2e-07 32.0 0.0 2.4e-07 31.1 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EGC35351.1 - 1.1e-05 25.0 0.1 1.9e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGC35351.1 - 0.007 16.9 0.0 0.02 15.4 0.0 1.9 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Ras PF00071.22 EGC35352.1 - 3e-24 85.4 0.9 4e-24 85.1 0.9 1.2 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35352.1 - 2.6e-06 27.7 0.2 9.9e-06 25.8 0.2 2.0 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_22 PF13401.6 EGC35353.1 - 2.3e-11 44.1 0.0 5.4e-11 42.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGC35353.1 - 1.6e-08 35.0 2.9 7.8e-08 32.8 0.1 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC35353.1 - 5.1e-08 33.5 0.0 3.8e-07 30.7 0.0 2.4 2 1 0 2 2 2 1 AAA ATPase domain AAA_14 PF13173.6 EGC35353.1 - 7.1e-06 26.1 0.2 3.8e-05 23.7 0.2 2.3 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGC35353.1 - 0.00019 21.3 0.1 0.024 14.3 0.1 2.3 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_7 PF12775.7 EGC35353.1 - 0.00039 20.0 0.2 0.0012 18.4 0.2 1.8 1 1 0 1 1 1 1 P-loop containing dynein motor region DUF2075 PF09848.9 EGC35353.1 - 0.0006 19.2 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) KTI12 PF08433.10 EGC35353.1 - 0.0019 17.7 0.5 0.11 11.9 0.0 2.5 2 1 0 2 2 2 1 Chromatin associated protein KTI12 NACHT PF05729.12 EGC35353.1 - 0.0032 17.4 0.0 0.0069 16.3 0.0 1.6 1 0 0 1 1 1 1 NACHT domain TK PF00265.18 EGC35353.1 - 0.0088 15.9 0.0 0.017 15.0 0.0 1.5 1 0 0 1 1 1 1 Thymidine kinase AAA_5 PF07728.14 EGC35353.1 - 0.0097 15.9 0.1 0.037 14.0 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TniB PF05621.11 EGC35353.1 - 0.016 14.6 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial TniB protein AAA_35 PF14516.6 EGC35353.1 - 0.021 13.7 3.1 0.31 9.8 0.5 2.7 2 1 0 2 2 2 0 AAA-like domain Cdc6_C PF09079.11 EGC35353.1 - 0.022 14.7 0.0 0.054 13.5 0.0 1.7 1 0 0 1 1 1 0 CDC6, C terminal winged helix domain AFG1_ATPase PF03969.16 EGC35353.1 - 0.034 13.0 0.0 0.059 12.3 0.0 1.3 1 0 0 1 1 1 0 AFG1-like ATPase Sigma54_activat PF00158.26 EGC35353.1 - 0.036 13.8 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGC35353.1 - 0.048 13.6 10.8 0.052 13.5 5.0 3.0 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGC35353.1 - 0.078 12.7 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC35353.1 - 0.17 12.3 2.4 0.22 11.9 0.2 2.5 2 2 0 2 2 2 0 RNA helicase Ploopntkinase3 PF18751.1 EGC35353.1 - 0.21 11.5 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 Par3_HAL_N_term PF12053.8 EGC35354.1 - 0.0038 17.4 0.0 0.013 15.7 0.0 2.0 1 0 0 1 1 1 1 N-terminal of Par3 and HAL proteins DUF4783 PF16022.5 EGC35354.1 - 0.028 14.6 0.3 0.11 12.6 0.3 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4783) MFS_1 PF07690.16 EGC35355.1 - 1.2e-15 57.3 34.5 3.7e-13 49.1 17.6 2.2 1 1 0 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGC35355.1 - 5.7e-13 48.2 10.5 5.7e-13 48.2 10.5 2.2 2 0 0 2 2 2 2 MFS/sugar transport protein DUF5364 PF17322.2 EGC35355.1 - 0.11 12.8 10.2 0.15 12.3 10.2 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5364) ECSCR PF15820.5 EGC35355.1 - 0.27 11.1 0.1 0.27 11.1 0.1 2.6 2 0 0 2 2 2 0 Endothelial cell-specific chemotaxis regulator DUF4014 PF13198.6 EGC35355.1 - 7.6 7.0 6.1 11 6.5 0.2 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4014) DP PF08781.10 EGC35356.1 - 4.5e-29 101.1 6.9 4.5e-29 101.1 6.9 3.7 4 0 0 4 4 4 1 Transcription factor DP E2F_TDP PF02319.20 EGC35356.1 - 2.1e-20 72.5 0.8 6.4e-20 71.0 0.8 1.9 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DUF3439 PF11921.8 EGC35356.1 - 0.16 11.9 4.1 0.55 10.2 4.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PAP2_3 PF14378.6 EGC35356.1 - 0.23 11.1 0.0 0.41 10.3 0.0 1.3 1 0 0 1 1 1 0 PAP2 superfamily ThiF PF00899.21 EGC35357.1 - 2.3e-99 331.7 0.0 4.7e-63 212.8 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGC35357.1 - 5.3e-76 255.9 8.1 5.3e-76 255.9 8.1 2.4 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_FCCH PF16190.5 EGC35357.1 - 9.9e-24 83.3 0.8 2.9e-23 81.8 0.8 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGC35357.1 - 4.3e-12 46.0 2.9 5.4e-12 45.7 0.6 2.5 2 0 0 2 2 2 1 Ubiquitin-activating enzyme E1 four-helix bundle E1_UFD PF09358.10 EGC35357.1 - 2.5e-10 40.9 0.0 1.4e-09 38.5 0.0 2.4 1 0 0 1 1 1 1 Ubiquitin fold domain Rubis-subs-bind PF09273.11 EGC35358.1 - 2.1e-09 38.2 0.2 5.3e-09 36.8 0.2 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.28 EGC35358.1 - 4.8e-08 33.6 2.3 8e-07 29.6 0.6 3.0 2 1 0 2 2 2 1 SET domain FDF PF09532.10 EGC35361.1 - 0.035 15.0 2.4 0.043 14.7 2.4 1.1 1 0 0 1 1 1 0 FDF domain DUF4690 PF15756.5 EGC35361.1 - 0.14 12.7 0.4 0.17 12.5 0.4 1.1 1 0 0 1 1 1 0 Small Novel Rich in Cartilage RRM_1 PF00076.22 EGC35362.1 - 1.2e-17 63.5 0.0 2e-17 62.8 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGC35362.1 - 7.8e-07 28.9 2.8 2.8e-06 27.1 2.8 2.1 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.6 EGC35362.1 - 7.8e-07 28.8 3.1 1.4e-06 28.0 3.1 1.4 1 0 0 1 1 1 1 Zinc knuckle Nup35_RRM_2 PF14605.6 EGC35362.1 - 0.0024 17.8 0.0 0.0038 17.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RL PF17797.1 EGC35362.1 - 0.04 13.9 0.0 0.066 13.2 0.0 1.3 1 0 0 1 1 1 0 RL domain zf-CCHC_3 PF13917.6 EGC35362.1 - 0.046 13.7 0.2 0.046 13.7 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle RRM_5 PF13893.6 EGC35362.1 - 0.06 12.9 0.0 0.082 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lactamase_B PF00753.27 EGC35363.1 - 3e-20 73.1 0.0 4.3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC35363.1 - 6.8e-06 25.7 0.1 1.1e-05 25.1 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RE_Eco47II PF09553.10 EGC35363.1 - 0.093 12.3 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Eco47II restriction endonuclease RNase_P_Rpp14 PF01900.19 EGC35364.1 - 7.2e-23 80.8 0.1 9.3e-23 80.4 0.1 1.1 1 0 0 1 1 1 1 Rpp14/Pop5 family RNase_H2_suC PF08615.11 EGC35365.1 - 1.1e-15 58.1 0.1 1.1e-15 58.1 0.1 1.8 1 1 1 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Get5_bdg PF16843.5 EGC35365.1 - 0.091 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein SRP_TPR_like PF17004.5 EGC35366.1 - 4.9e-20 71.7 15.8 5.6e-18 65.1 5.5 3.8 2 2 1 4 4 4 2 Putative TPR-like repeat TPR_19 PF14559.6 EGC35366.1 - 3.1e-18 66.0 6.8 0.0043 17.5 0.1 8.4 4 2 3 8 8 8 5 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC35366.1 - 3.4e-14 52.8 31.3 8e-05 22.8 0.2 7.2 4 1 3 7 7 7 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGC35366.1 - 1.5e-13 49.8 21.4 0.017 15.2 0.1 9.2 10 1 1 11 11 9 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGC35366.1 - 1.5e-12 46.8 27.0 0.004 16.9 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_14 PF13428.6 EGC35366.1 - 6.4e-10 39.0 0.0 0.16 12.9 0.0 7.1 7 2 2 9 9 7 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC35366.1 - 1.5e-09 38.0 9.4 0.96 9.8 0.0 7.7 5 2 1 6 6 6 3 Tetratricopeptide repeat SRP72 PF08492.12 EGC35366.1 - 5.1e-09 36.4 4.4 5.1e-09 36.4 4.4 3.2 2 0 0 2 2 1 1 SRP72 RNA-binding domain TPR_7 PF13176.6 EGC35366.1 - 5.3e-09 35.5 2.8 4.9 7.4 0.0 7.2 6 1 0 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC35366.1 - 3.5e-06 27.3 10.9 27 5.7 0.1 8.1 9 0 0 9 9 8 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC35366.1 - 1.9e-05 25.2 0.0 13 6.6 0.0 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC35366.1 - 0.00011 22.2 4.6 1.4 9.1 0.1 5.5 6 1 0 6 6 6 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.6 EGC35366.1 - 0.0002 21.5 0.0 2.1 8.6 0.0 4.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC35366.1 - 0.00023 21.1 24.0 6 7.4 0.0 9.0 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC35366.1 - 0.00059 19.5 6.5 12 5.7 0.0 6.1 5 1 1 6 6 6 0 TPR repeat TPR_15 PF13429.6 EGC35366.1 - 0.012 14.8 1.9 1.3 8.2 0.4 3.6 3 1 1 4 4 4 0 Tetratricopeptide repeat Alkyl_sulf_dimr PF14863.6 EGC35366.1 - 0.046 14.2 0.3 4.9 7.6 0.0 3.4 3 0 0 3 3 3 0 Alkyl sulfatase dimerisation QVR PF17064.5 EGC35366.1 - 5.6 7.3 8.2 0.51 10.6 1.7 2.4 2 0 0 2 2 2 0 Sleepless protein AMP-binding PF00501.28 EGC35369.1 - 2.5e-64 217.5 0.0 3.1e-64 217.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC35369.1 - 1.8e-12 47.0 3.8 1.8e-12 47.0 3.8 2.0 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC35369.1 - 4.7e-06 27.5 0.0 8.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pec_lyase_C PF00544.19 EGC35369.1 - 0.041 13.5 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Pectate lyase BACK PF07707.15 EGC35370.1 - 0.012 15.6 0.0 2.2 8.4 0.0 2.7 2 0 0 2 2 2 0 BTB And C-terminal Kelch Orn_Arg_deC_N PF02784.16 EGC35371.1 - 1.2e-41 142.8 0.0 1.5e-41 142.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGC35371.1 - 3.1e-10 40.2 0.0 4.5e-10 39.6 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ras PF00071.22 EGC35372.1 - 4.8e-33 114.0 0.1 6.1e-33 113.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35372.1 - 2.5e-16 60.0 0.0 4.7e-16 59.1 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35372.1 - 7.1e-09 35.4 0.0 9.6e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC35372.1 - 0.00011 21.8 0.1 0.00035 20.2 0.0 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC35372.1 - 0.0018 18.3 0.1 0.0047 17.0 0.0 1.7 2 1 0 2 2 2 1 50S ribosome-binding GTPase TRP_2 PF08344.11 EGC35372.1 - 0.054 13.7 0.2 0.37 11.0 0.3 2.3 2 1 0 2 2 2 0 Transient receptor ion channel II CRAL_TRIO_2 PF13716.6 EGC35372.1 - 0.073 13.2 0.5 0.12 12.6 0.5 1.3 1 0 0 1 1 1 0 Divergent CRAL/TRIO domain Pox_D5 PF03288.16 EGC35372.1 - 0.09 13.3 0.7 0.18 12.3 0.7 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like Tam41_Mmp37 PF09139.11 EGC35374.1 - 7.1e-64 216.3 18.9 1.8e-52 178.8 7.2 2.5 2 1 1 3 3 3 2 Phosphatidate cytidylyltransferase, mitochondrial DUF668 PF05003.12 EGC35374.1 - 0.12 12.8 0.1 0.74 10.3 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF668) Glyco_hydro_15 PF00723.21 EGC35375.1 - 2.8e-55 187.9 0.0 5.1e-52 177.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 MCM PF00493.23 EGC35376.1 - 5.9e-101 336.3 0.0 9.1e-101 335.6 0.0 1.3 1 0 0 1 1 1 1 MCM P-loop domain MCM_OB PF17207.3 EGC35376.1 - 5.2e-35 120.0 0.3 1.4e-34 118.6 0.0 1.9 2 0 0 2 2 2 1 MCM OB domain MCM_lid PF17855.1 EGC35376.1 - 1.2e-27 96.2 0.1 1.8e-26 92.4 0.0 2.6 2 0 0 2 2 2 1 MCM AAA-lid domain MCM_N PF14551.6 EGC35376.1 - 2.1e-12 47.6 7.7 7.4e-12 45.8 7.7 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGC35376.1 - 1e-07 31.6 1.5 4.1e-05 23.1 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC35376.1 - 8.1e-07 29.1 0.0 4.3e-06 26.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGC35376.1 - 0.011 15.6 0.0 0.042 13.7 0.0 2.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Viral_NABP PF05515.11 EGC35376.1 - 0.02 14.7 0.0 0.031 14.1 0.0 1.3 1 0 0 1 1 1 0 Viral nucleic acid binding AAA PF00004.29 EGC35376.1 - 0.072 13.5 0.0 0.25 11.8 0.0 2.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC35376.1 - 0.11 12.2 0.0 16 5.2 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_16 PF13191.6 EGC35376.1 - 0.4 11.0 4.2 0.55 10.6 0.1 3.4 3 1 1 4 4 4 0 AAA ATPase domain AAA_22 PF13401.6 EGC35376.1 - 0.41 10.9 3.1 22 5.3 0.1 3.4 3 1 0 3 3 3 0 AAA domain SUIM_assoc PF16619.5 EGC35376.1 - 0.56 10.3 8.9 0.28 11.3 5.0 2.5 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 DUF4634 PF15465.6 EGC35378.1 - 3.9 7.8 6.8 6.7 7.0 5.1 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) ArgJ PF01960.18 EGC35379.1 - 2.7e-141 470.7 13.2 3e-141 470.5 13.2 1.0 1 0 0 1 1 1 1 ArgJ family DUF1573 PF07610.11 EGC35379.1 - 0.026 14.5 0.2 0.33 11.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1573) ATG_C PF09333.11 EGC35379.1 - 0.065 13.6 0.2 3.1 8.2 0.0 2.7 2 0 0 2 2 2 0 Autophagy-related protein C terminal domain CK2S PF15011.6 EGC35380.1 - 1.2e-05 25.2 2.8 0.014 15.3 0.7 2.6 2 1 0 2 2 2 2 Casein Kinase 2 substrate Calcyon PF06387.11 EGC35380.1 - 0.038 14.0 0.1 4.6 7.2 0.0 2.5 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) DUF4834 PF16118.5 EGC35380.1 - 0.093 13.7 4.8 0.24 12.4 4.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Neur_chan_memb PF02932.16 EGC35380.1 - 0.7 9.9 5.9 0.87 9.6 4.8 1.7 1 1 1 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region APC1_C PF18122.1 EGC35380.1 - 0.97 9.4 4.9 1.5 8.8 4.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex sub unit 1 C-terminal domain POX PF07526.11 EGC35380.1 - 2.5 8.7 9.2 5.7 7.5 9.2 1.7 1 1 0 1 1 1 0 Associated with HOX Acyltransferase PF01553.21 EGC35381.1 - 1.2e-26 92.9 0.0 1.7e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase Methyltransf_16 PF10294.9 EGC35383.1 - 3.1e-21 75.9 0.0 6.9e-21 74.7 0.0 1.6 1 1 1 2 2 2 1 Lysine methyltransferase MTS PF05175.14 EGC35383.1 - 0.0059 16.2 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain BOF PF04076.13 EGC35383.1 - 0.019 15.0 0.5 0.036 14.1 0.5 1.4 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein A_thal_3526 PF09713.10 EGC35384.1 - 3.1e-18 65.7 2.1 3.1e-18 65.7 2.1 1.9 2 0 0 2 2 2 1 Plant protein 1589 of unknown function (A_thal_3526) ECH_2 PF16113.5 EGC35384.1 - 0.015 14.8 2.4 0.4 10.1 0.0 2.4 2 0 0 2 2 2 0 Enoyl-CoA hydratase/isomerase Tox-HNH-HHH PF15637.6 EGC35384.1 - 0.059 13.5 0.9 0.22 11.7 0.9 2.0 1 0 0 1 1 1 0 HNH/Endo VII superfamily nuclease toxin with a HHH motif COMM_domain PF07258.14 EGC35385.1 - 6.3e-18 64.7 6.0 1.2e-17 63.8 6.0 1.4 1 1 0 1 1 1 1 COMM domain UBA_e1_thiolCys PF10585.9 EGC35385.1 - 0.033 14.1 1.3 0.037 13.9 1.3 1.0 1 0 0 1 1 1 0 Ubiquitin-activating enzyme active site Pkinase_Tyr PF07714.17 EGC35386.1 - 3.2e-65 220.0 0.7 3.2e-64 216.7 0.0 2.5 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35386.1 - 5.6e-53 180.0 0.0 5.6e-53 180.0 0.0 3.7 4 1 0 4 4 4 1 Protein kinase domain LRR_8 PF13855.6 EGC35386.1 - 3.2e-20 71.6 42.6 2.3e-08 33.6 7.1 3.6 1 1 3 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGC35386.1 - 5.6e-17 61.6 44.2 9.9e-08 32.2 5.6 6.0 4 1 3 7 7 7 5 Leucine Rich repeats (2 copies) APH PF01636.23 EGC35386.1 - 0.0023 17.9 0.1 0.0023 17.9 0.1 2.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family LRR_6 PF13516.6 EGC35386.1 - 0.011 15.8 0.2 0.011 15.8 0.2 5.9 6 0 0 6 6 6 0 Leucine Rich repeat LRR_1 PF00560.33 EGC35386.1 - 0.062 13.9 25.4 2.6 8.9 0.3 8.7 7 1 0 7 7 7 0 Leucine Rich Repeat LRR_3 PF07725.12 EGC35386.1 - 0.079 12.8 3.3 0.25 11.3 0.3 2.8 2 0 0 2 2 2 0 Leucine Rich Repeat GATA PF00320.27 EGC35387.1 - 1.5e-16 59.7 4.1 1.5e-16 59.7 4.1 1.9 2 0 0 2 2 2 1 GATA zinc finger OrfB_Zn_ribbon PF07282.11 EGC35387.1 - 0.11 12.5 1.9 0.35 10.8 1.9 1.9 1 0 0 1 1 1 0 Putative transposase DNA-binding domain PhoPQ_related PF10142.9 EGC35388.1 - 1.8e-136 454.7 2.4 2e-136 454.4 2.4 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein LMBR1 PF04791.16 EGC35389.1 - 4e-120 402.1 18.7 5.1e-120 401.8 18.7 1.0 1 0 0 1 1 1 1 LMBR1-like membrane protein Dus PF01207.17 EGC35390.1 - 3.8e-74 249.6 0.0 7.8e-74 248.5 0.0 1.6 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.21 EGC35390.1 - 0.0097 15.4 0.0 0.018 14.5 0.0 1.4 1 0 0 1 1 1 1 Histidine biosynthesis protein Fibrillarin_2 PF10113.9 EGC35390.1 - 0.051 12.2 1.0 0.065 11.9 0.0 1.6 2 0 0 2 2 2 0 Fibrillarin-like archaeal protein FMN_dh PF01070.18 EGC35390.1 - 0.17 10.9 0.0 0.26 10.3 0.0 1.2 1 0 0 1 1 1 0 FMN-dependent dehydrogenase ThiG PF05690.14 EGC35390.1 - 0.2 11.0 0.0 0.3 10.4 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG MDM10 PF12519.8 EGC35391.1 - 5.6e-08 32.1 1.7 6.4e-08 31.9 1.7 1.1 1 0 0 1 1 1 1 Mitochondrial distribution and morphology protein 10 Porin_3 PF01459.22 EGC35391.1 - 0.018 14.5 0.7 0.031 13.7 0.7 1.6 1 1 0 1 1 1 0 Eukaryotic porin DUF4264 PF14084.6 EGC35391.1 - 0.025 14.2 1.5 0.22 11.2 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) FixG_C PF11614.8 EGC35391.1 - 0.1 12.8 0.1 0.17 12.1 0.1 1.3 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase Suv3_C_1 PF18147.1 EGC35393.1 - 2.2e-12 46.6 0.3 4.7e-12 45.6 0.3 1.6 1 0 0 1 1 1 1 Suv3 C-terminal domain 1 Helicase_C PF00271.31 EGC35393.1 - 4.1e-11 43.2 0.0 1.1e-10 41.9 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.8 EGC35393.1 - 1.9e-10 40.5 0.1 5.1e-10 39.1 0.1 1.8 1 0 0 1 1 1 1 Mitochondrial degradasome RNA helicase subunit C terminal DUF3439 PF11921.8 EGC35394.1 - 0.3 11.1 12.9 0.023 14.6 5.3 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Pkinase_Tyr PF07714.17 EGC35395.1 - 5.2e-59 199.6 0.0 8.1e-59 199.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35395.1 - 3.8e-51 174.0 0.1 1.2e-50 172.4 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 EGC35395.1 - 1.5e-16 60.7 1.9 5.7e-16 58.9 1.9 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain Atrophin-1 PF03154.15 EGC35395.1 - 1.8e-05 23.3 3.1 1.8e-05 23.3 3.1 1.6 2 0 0 2 2 2 1 Atrophin-1 family Kinase-like PF14531.6 EGC35395.1 - 0.011 15.0 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.23 EGC35395.1 - 0.097 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RSB_motif PF16294.5 EGC35395.1 - 0.73 10.1 18.8 1.4 9.2 0.6 2.5 2 0 0 2 2 2 0 RNSP1-SAP18 binding (RSB) motif LMBR1 PF04791.16 EGC35395.1 - 2.4 7.0 7.9 3.5 6.4 7.9 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.9 EGC35395.1 - 8 4.9 31.9 0.22 10.1 24.2 1.9 2 0 0 2 2 2 0 Macoilin family Cnd3 PF12719.7 EGC35396.1 - 5.1e-20 71.9 9.4 5.1e-20 71.9 9.4 3.5 4 0 0 4 4 4 2 Nuclear condensing complex subunits, C-term domain CdiI_2 PF18593.1 EGC35396.1 - 0.028 15.1 0.8 2.4 8.9 0.1 3.6 3 0 0 3 3 3 0 CdiI immunity protein Dicty_CTDC PF00526.18 EGC35397.1 - 1.6e-08 34.3 27.4 1.8e-06 27.7 12.1 5.6 8 0 0 8 8 8 2 Dictyostelium (slime mold) repeat MARVEL PF01284.23 EGC35398.1 - 3.1 7.8 10.4 1.8 8.6 5.3 2.2 2 1 0 2 2 2 0 Membrane-associating domain TctB PF07331.11 EGC35398.1 - 4.2 7.6 13.0 2.1 8.6 9.7 2.1 2 1 0 2 2 2 0 Tripartite tricarboxylate transporter TctB family R3H-assoc PF13902.6 EGC35399.1 - 0.025 14.9 0.7 0.059 13.8 0.7 1.6 2 0 0 2 2 2 0 R3H-associated N-terminal domain DUF3718 PF12514.8 EGC35399.1 - 0.063 13.4 0.5 0.12 12.5 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3718) DUF3450 PF11932.8 EGC35399.1 - 0.17 11.1 1.9 1.5 8.1 0.4 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3450) SGP PF17228.2 EGC35399.1 - 1.2 10.0 10.2 0.37 11.7 3.0 2.3 2 0 0 2 2 2 0 Sulphur globule protein DUF2796 PF10986.8 EGC35399.1 - 5.6 6.9 31.3 2.4 8.1 29.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) Cellulase PF00150.18 EGC35400.1 - 2.8e-10 40.1 4.4 4.2e-10 39.5 4.4 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.15 EGC35400.1 - 6.7e-09 35.6 0.5 9.8e-09 35.0 0.5 1.2 1 0 0 1 1 1 1 Beta-galactosidase Glyco_hydro_14 PF01373.17 EGC35400.1 - 0.0028 16.7 1.2 0.0046 16.0 1.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 14 Asp PF00026.23 EGC35401.1 - 2.6e-115 385.2 2.1 3e-115 385.0 2.1 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGC35401.1 - 2.7e-15 57.1 4.0 5.4e-13 49.6 4.0 2.4 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.6 EGC35401.1 - 0.0004 21.0 0.0 0.012 16.2 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease TAXi_C PF14541.6 EGC35401.1 - 0.00058 19.7 0.0 0.0015 18.4 0.0 1.6 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal gag-asp_proteas PF13975.6 EGC35401.1 - 0.0036 17.8 0.0 0.02 15.4 0.0 2.2 1 1 1 2 2 2 1 gag-polyprotein putative aspartyl protease Big_11 PF18200.1 EGC35401.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 1 0 1 1 1 0 Bacterial Ig-like domain Oxidored_FMN PF00724.20 EGC35402.1 - 1.1e-76 258.3 0.0 1.3e-76 258.1 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.17 EGC35402.1 - 0.019 14.1 0.0 0.037 13.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) AMP-binding PF00501.28 EGC35403.1 - 2.4e-84 283.4 0.0 3e-84 283.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC35403.1 - 2.2e-23 83.0 0.5 4.7e-23 82.0 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC35403.1 - 6.7e-16 57.9 1.8 1.5e-15 56.9 1.8 1.6 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus TPR_12 PF13424.6 EGC35404.1 - 8.6e-31 106.1 0.7 6.7e-07 29.5 0.0 6.7 6 1 0 7 7 6 5 Tetratricopeptide repeat TPR_1 PF00515.28 EGC35404.1 - 1.9e-11 43.3 30.8 0.0042 16.8 0.3 10.2 11 1 0 11 11 11 4 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.6 EGC35404.1 - 4.5e-11 43.5 0.0 2.8e-10 40.9 0.0 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.17 EGC35404.1 - 4.6e-10 38.8 19.7 0.16 12.1 0.0 9.3 10 0 0 10 10 9 3 Tetratricopeptide repeat Actin PF00022.19 EGC35404.1 - 9.7e-08 31.0 0.0 2.2e-05 23.2 0.0 2.7 2 0 0 2 2 2 1 Actin F-box-like PF12937.7 EGC35404.1 - 1.8e-06 27.7 0.8 4.7e-06 26.4 0.8 1.8 1 0 0 1 1 1 1 F-box-like DUF2974 PF11187.8 EGC35404.1 - 6.3e-06 25.9 0.0 1.7e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) TPR_8 PF13181.6 EGC35404.1 - 4e-05 23.5 27.4 0.8 10.1 0.6 9.3 9 0 0 9 9 9 3 Tetratricopeptide repeat MIT PF04212.18 EGC35404.1 - 6.2e-05 23.0 13.3 0.013 15.6 0.1 5.3 5 0 0 5 5 5 2 MIT (microtubule interacting and transport) domain Lipase_3 PF01764.25 EGC35404.1 - 7.2e-05 22.7 0.0 0.00031 20.6 0.0 2.0 1 0 0 1 1 1 1 Lipase (class 3) F-box PF00646.33 EGC35404.1 - 9.2e-05 22.2 1.6 0.00045 20.0 0.3 2.6 2 0 0 2 2 2 1 F-box domain TPR_7 PF13176.6 EGC35404.1 - 0.00066 19.5 2.4 5.1 7.4 0.0 5.1 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC35404.1 - 0.0098 16.5 0.1 83 4.1 0.0 6.0 7 0 0 7 7 5 0 Tetratricopeptide repeat AAA_22 PF13401.6 EGC35404.1 - 0.012 15.8 0.1 0.091 13.0 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC35404.1 - 0.062 13.1 0.0 0.19 11.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_10 PF13374.6 EGC35404.1 - 0.11 12.4 0.4 21 5.2 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat ABC_tran PF00005.27 EGC35404.1 - 0.12 12.8 1.8 1.7 9.2 0.0 3.2 2 0 0 2 2 2 0 ABC transporter DUF4446 PF14584.6 EGC35404.1 - 0.36 10.8 10.7 2.8 7.9 0.1 4.1 4 0 0 4 4 3 0 Protein of unknown function (DUF4446) Ubiquitin_2 PF14560.6 EGC35404.1 - 0.38 11.2 4.0 5.5 7.5 0.2 3.5 2 0 0 2 2 2 0 Ubiquitin-like domain TPR_17 PF13431.6 EGC35404.1 - 0.83 10.2 8.8 52 4.6 0.0 6.0 7 0 0 7 7 6 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGC35404.1 - 1.6 8.4 14.4 5.7 6.7 0.1 6.5 7 0 0 7 7 7 0 TPR repeat ANAPC3 PF12895.7 EGC35404.1 - 3.4 7.9 13.6 6.5 7.1 0.2 5.3 2 1 2 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 FNIP PF05725.12 EGC35405.1 - 1.4e-47 159.6 60.0 4.4e-09 36.4 2.3 12.9 4 3 8 14 14 14 14 FNIP Repeat zf-B_box PF00643.24 EGC35405.1 - 2.8e-05 24.2 6.4 8.6e-05 22.6 6.4 1.8 1 0 0 1 1 1 1 B-box zinc finger FNIP PF05725.12 EGC35406.1 - 9.1e-41 137.8 40.8 7.7e-14 51.6 6.6 6.5 4 2 2 6 6 6 5 FNIP Repeat DUF1769 PF08588.10 EGC35406.1 - 0.016 15.4 3.9 5.4 7.3 0.1 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF1769) LRR_8 PF13855.6 EGC35406.1 - 2.5 7.9 11.8 2.9 7.7 1.5 3.6 4 0 0 4 4 4 0 Leucine rich repeat VWC PF00093.18 EGC35408.1 - 0.0023 18.2 60.1 0.47 10.8 9.7 4.1 4 0 0 4 4 4 4 von Willebrand factor type C domain IGFBP PF00219.18 EGC35408.1 - 0.49 11.1 54.1 0.15 12.8 18.0 3.7 1 1 3 4 4 4 0 Insulin-like growth factor binding protein TPR_12 PF13424.6 EGC35409.1 - 5.1e-05 23.5 0.0 2.1 8.7 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC35409.1 - 0.0016 18.4 1.8 0.031 14.4 0.6 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC35409.1 - 0.0082 15.9 0.4 0.1 12.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat PAN_4 PF14295.6 EGC35410.1 - 4.4e-10 39.3 1.5 4.4e-10 39.3 1.5 3.4 3 0 0 3 3 3 1 PAN domain SpoVAD PF07451.11 EGC35410.1 - 0.54 8.9 2.6 0.9 8.2 2.6 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) AMP-binding PF00501.28 EGC35411.1 - 2.5e-82 276.7 0.0 3.3e-82 276.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC35411.1 - 4.3e-23 82.1 0.5 9.1e-23 81.0 0.5 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC35411.1 - 0.00027 20.8 6.1 0.0016 18.3 3.4 2.9 2 1 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus DUF4065 PF13274.6 EGC35411.1 - 4.9 8.1 6.9 0.97 10.3 1.4 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4065) Cyclin PF08613.11 EGC35412.1 - 0.00079 19.8 0.7 0.00079 19.8 0.7 3.9 4 0 0 4 4 4 2 Cyclin DUF2462 PF09495.10 EGC35413.1 - 0.43 11.3 7.9 2.3 9.0 1.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) NifU_N PF01592.16 EGC35414.1 - 9e-54 181.1 0.2 1.1e-53 180.7 0.2 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Peptidase_S24 PF00717.23 EGC35415.1 - 1.1e-08 34.9 0.1 3.6e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Peptidase S24-like CSG2 PF16965.5 EGC35415.1 - 0.0024 16.9 1.3 0.0032 16.5 1.3 1.1 1 0 0 1 1 1 1 Ceramide synthase regulator PDCD2_C PF04194.13 EGC35415.1 - 0.0078 16.3 1.1 0.01 15.9 1.1 1.2 1 0 0 1 1 1 1 Programmed cell death protein 2, C-terminal putative domain Peptidase_S26 PF10502.9 EGC35415.1 - 0.017 14.9 0.0 0.051 13.4 0.0 1.7 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 PNISR PF15996.5 EGC35415.1 - 0.028 14.7 0.5 0.038 14.3 0.5 1.1 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR CLN3 PF02487.17 EGC35415.1 - 0.56 9.2 2.2 0.73 8.8 2.2 1.1 1 0 0 1 1 1 0 CLN3 protein DUF1748 PF08520.10 EGC35416.1 - 7.2e-06 25.8 0.7 0.1 12.5 0.3 2.0 1 1 1 2 2 2 2 Fungal protein of unknown function (DUF1748) 4_1_CTD PF05902.13 EGC35417.1 - 0.006 16.6 1.1 0.014 15.5 1.1 1.6 1 0 0 1 1 1 1 4.1 protein C-terminal domain (CTD) Tfb5 PF06331.12 EGC35417.1 - 0.35 10.9 2.4 3.7 7.6 0.2 2.4 2 0 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 PH_4 PF15404.6 EGC35417.1 - 1.6 8.5 10.4 1.9 8.3 9.4 1.6 1 1 0 1 1 1 0 Pleckstrin homology domain TMEM169 PF15052.6 EGC35417.1 - 9.3 6.4 12.5 2.3 8.3 0.5 2.2 1 1 1 2 2 2 0 TMEM169 protein family Ribosomal_L34e PF01199.18 EGC35418.1 - 0.15 12.3 2.1 0.61 10.4 0.1 2.5 2 0 0 2 2 2 0 Ribosomal protein L34e DUF4637 PF15470.6 EGC35418.1 - 7.2 6.3 5.9 2.2 8.0 2.5 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4637) RNase_T PF00929.24 EGC35419.1 - 3.3e-29 102.5 0.0 4e-29 102.3 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Staufen_C PF16482.5 EGC35419.1 - 0.22 11.7 1.3 0.23 11.7 0.2 1.6 2 0 0 2 2 2 0 Staufen C-terminal domain GCV_H PF01597.19 EGC35420.1 - 1.1e-34 118.9 0.1 1.4e-34 118.6 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.6 EGC35420.1 - 0.069 13.1 0.0 0.29 11.1 0.0 1.9 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain CBP_BcsG PF11658.8 EGC35421.1 - 0.0045 15.5 0.1 0.0073 14.8 0.1 1.3 1 0 0 1 1 1 1 Cellulose biosynthesis protein BcsG DUF4834 PF16118.5 EGC35421.1 - 0.068 14.1 0.5 0.068 14.1 0.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) Glucos_trans_II PF14264.6 EGC35421.1 - 0.073 12.4 17.6 0.066 12.6 12.7 2.1 2 0 0 2 2 2 0 Glucosyl transferase GtrII DUF2759 PF10958.8 EGC35421.1 - 0.4 10.5 9.0 1.5 8.6 9.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2759) DUF3792 PF12670.7 EGC35421.1 - 1.1 9.5 14.3 3.5 7.8 4.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF2070 PF09843.9 EGC35422.1 - 0.1 10.9 3.5 0.11 10.7 3.5 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) PrgI PF12666.7 EGC35422.1 - 0.41 11.4 6.9 0.69 10.7 0.8 2.6 3 0 0 3 3 3 0 PrgI family protein Holin_SPP1 PF04688.13 EGC35422.1 - 0.89 9.8 0.0 0.89 9.8 0.0 3.1 3 1 0 3 3 3 0 SPP1 phage holin 4HB_MCP_1 PF12729.7 EGC35422.1 - 1.7 8.2 3.4 0.9 9.1 0.1 2.0 2 0 0 2 2 2 0 Four helix bundle sensory module for signal transduction MARVEL PF01284.23 EGC35423.1 - 0.12 12.4 9.3 0.28 11.2 9.4 1.5 1 1 0 1 1 1 0 Membrane-associating domain DuoxA PF10204.9 EGC35423.1 - 0.56 9.2 14.6 0.0068 15.4 6.7 1.7 2 0 0 2 2 2 0 Dual oxidase maturation factor Wzy_C PF04932.15 EGC35423.1 - 8.5 6.0 9.1 11 5.7 0.4 2.5 3 0 0 3 3 3 0 O-Antigen ligase zf-TRAF PF02176.18 EGC35424.1 - 1.9e-18 66.9 18.6 2.4e-13 50.5 7.7 4.8 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EGC35424.1 - 1.2e-07 31.4 13.2 1.2e-07 31.4 13.2 3.2 2 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC35424.1 - 2.5e-06 27.3 11.3 2.5e-06 27.3 11.3 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC35424.1 - 0.00015 21.8 17.9 0.00031 20.7 2.2 3.8 2 1 2 4 4 4 3 Seven in absentia protein family zf-RING_2 PF13639.6 EGC35424.1 - 0.00062 20.0 12.5 0.00062 20.0 12.5 3.8 3 1 1 4 4 4 1 Ring finger domain zf-TRAF_2 PF15965.5 EGC35424.1 - 0.011 16.2 10.1 0.011 16.2 10.1 4.0 1 1 2 3 3 3 0 TRAF-like zinc-finger zf_C2HC_14 PF18574.1 EGC35424.1 - 0.41 10.5 24.3 0.68 9.8 0.5 6.0 6 0 0 6 6 6 0 C2HC Zing finger domain Lectin_N PF03954.14 EGC35425.1 - 0.23 11.2 0.4 0.25 11.1 0.4 1.2 1 0 0 1 1 1 0 Hepatic lectin, N-terminal domain Ibs_toxin PF13956.6 EGC35425.1 - 0.65 10.1 9.8 1.2 9.3 9.8 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Yae1_N PF09811.9 EGC35426.1 - 0.36 10.6 3.1 11 5.8 0.2 2.4 2 0 0 2 2 2 0 Essential protein Yae1, N terminal zf-C2HC5 PF06221.13 EGC35427.1 - 1e-15 57.4 8.7 1.9e-15 56.6 8.7 1.4 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type CdiI PF07262.11 EGC35427.1 - 0.0011 18.8 2.1 0.0011 18.8 2.1 2.3 2 1 0 2 2 2 1 CDI immunity protein Dna2 PF08696.11 EGC35427.1 - 2 8.2 9.7 1.6 8.5 4.7 2.7 2 0 0 2 2 2 0 DNA replication factor Dna2 ORC4_C PF14629.6 EGC35427.1 - 2.3 7.5 7.8 0.37 10.1 0.9 2.8 2 1 0 2 2 2 0 Origin recognition complex (ORC) subunit 4 C-terminus SnoaL_2 PF12680.7 EGC35428.1 - 0.00058 20.5 0.0 1.2 9.9 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain SnoaL_3 PF13474.6 EGC35428.1 - 0.0047 17.2 0.0 4.7 7.5 0.0 2.8 2 0 0 2 2 2 2 SnoaL-like domain DDE_Tnp_4 PF13359.6 EGC35431.1 - 0.0015 18.2 0.0 0.0085 15.8 0.0 2.1 1 1 0 1 1 1 1 DDE superfamily endonuclease Acyl-CoA_dh_M PF02770.19 EGC35432.1 - 1.6e-11 44.2 0.0 3.1e-11 43.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC35432.1 - 4.9e-11 43.1 0.1 8.4e-11 42.3 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.19 EGC35432.1 - 2.4e-09 37.0 0.3 6.6e-09 35.6 0.1 1.8 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.6 EGC35432.1 - 0.0045 17.5 0.1 0.0094 16.5 0.1 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal TRI5 PF06330.11 EGC35432.1 - 0.035 13.0 0.2 0.053 12.4 0.2 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) BTB PF00651.31 EGC35433.1 - 4.1e-22 78.5 0.2 4.1e-22 78.5 0.2 2.5 3 1 1 4 4 4 1 BTB/POZ domain BACK PF07707.15 EGC35433.1 - 0.00028 20.9 1.5 0.42 10.8 0.0 4.1 4 1 0 4 4 4 1 BTB And C-terminal Kelch Presenilin PF01080.17 EGC35433.1 - 4.3 6.0 7.4 1.9 7.2 4.8 1.6 2 0 0 2 2 2 0 Presenilin Macoilin PF09726.9 EGC35433.1 - 8.5 4.8 22.1 0.12 11.0 14.6 1.5 2 0 0 2 2 2 0 Macoilin family Snapin_Pallidin PF14712.6 EGC35434.1 - 2.2e-21 76.1 0.2 2.2e-21 76.1 0.2 2.2 2 0 0 2 2 2 1 Snapin/Pallidin GCN5L1 PF06320.13 EGC35434.1 - 0.0013 18.9 4.0 0.014 15.6 0.2 2.3 2 1 0 2 2 2 1 GCN5-like protein 1 (GCN5L1) COG5 PF10392.9 EGC35434.1 - 0.0033 17.6 6.4 0.0033 17.6 6.4 1.6 1 1 0 2 2 2 1 Golgi transport complex subunit 5 HTH_1 PF00126.27 EGC35434.1 - 0.011 15.7 0.4 0.14 12.1 0.0 2.5 2 0 0 2 2 2 0 Bacterial regulatory helix-turn-helix protein, lysR family SlyX PF04102.12 EGC35434.1 - 0.014 16.0 3.4 0.17 12.5 1.3 2.6 2 0 0 2 2 2 0 SlyX DUF948 PF06103.11 EGC35434.1 - 0.11 12.8 1.1 1.6 9.0 0.0 2.5 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) TMF_DNA_bd PF12329.8 EGC35434.1 - 0.7 9.9 0.1 0.7 9.9 0.1 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding Prefoldin_2 PF01920.20 EGC35434.1 - 0.82 9.7 14.1 0.097 12.6 3.7 2.9 3 1 0 3 3 3 0 Prefoldin subunit ING PF12998.7 EGC35434.1 - 1.4 9.6 11.1 0.44 11.2 0.5 2.9 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding Nucleotid_trans PF03407.16 EGC35435.1 - 1.1e-32 113.7 0.8 2.1e-32 112.8 0.1 1.8 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase WD40 PF00400.32 EGC35435.1 - 1.5e-28 98.4 17.5 7.9e-05 23.4 0.1 7.2 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.8 EGC35435.1 - 0.00017 20.4 6.0 0.044 12.4 0.1 4.4 2 1 2 5 5 5 2 Nucleoporin Nup120/160 DUF2294 PF10057.9 EGC35435.1 - 0.11 12.7 0.1 3.5 7.8 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2294) ABC_tran PF00005.27 EGC35436.1 - 1.7e-33 116.0 0.0 3.5e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.23 EGC35436.1 - 2e-31 109.7 10.5 2.9e-31 109.1 10.5 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.19 EGC35436.1 - 0.00011 21.8 0.0 0.00025 20.6 0.0 1.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGC35436.1 - 0.016 15.1 0.1 0.034 14.1 0.1 1.5 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EGC35436.1 - 0.05 13.9 1.2 0.58 10.4 0.2 2.8 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC35436.1 - 0.052 13.3 0.2 0.13 12.0 0.2 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGC35436.1 - 0.076 13.1 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_16 PF13191.6 EGC35436.1 - 0.15 12.4 0.0 0.36 11.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain MCM PF00493.23 EGC35437.1 - 2.8e-99 330.8 0.3 1.3e-98 328.6 0.0 2.3 3 0 0 3 3 3 1 MCM P-loop domain MCM_OB PF17207.3 EGC35437.1 - 5.5e-31 107.0 0.2 1e-30 106.2 0.2 1.4 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC35437.1 - 2.3e-21 76.0 0.2 4.9e-21 75.0 0.2 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGC35437.1 - 4.3e-10 40.1 3.9 1.5e-09 38.4 3.9 2.0 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGC35437.1 - 7.7e-08 32.0 0.2 2.9e-05 23.6 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC35437.1 - 1.3e-06 28.4 0.0 1e-05 25.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGC35437.1 - 0.0011 18.8 0.0 0.0047 16.8 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_C PF13335.6 EGC35437.1 - 0.011 16.4 0.1 0.076 13.7 0.0 2.5 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI C-terminal AAA_lid_2 PF17863.1 EGC35437.1 - 0.011 15.6 0.0 0.025 14.4 0.0 1.5 1 0 0 1 1 1 0 AAA lid domain PLA2_B PF01735.18 EGC35437.1 - 0.06 11.7 0.9 0.11 10.9 0.9 1.3 1 0 0 1 1 1 0 Lysophospholipase catalytic domain AAA_16 PF13191.6 EGC35437.1 - 0.16 12.4 0.2 2 8.8 0.0 2.3 1 1 1 2 2 2 0 AAA ATPase domain EGF_2 PF07974.13 EGC35438.1 - 4.8e-05 23.6 37.3 0.058 13.8 9.9 3.7 2 1 1 3 3 3 3 EGF-like domain LRR_4 PF12799.7 EGC35438.1 - 0.024 15.1 0.9 2.2 8.8 0.1 3.5 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) ATPase PF06745.13 EGC35438.1 - 0.041 13.2 0.7 0.82 9.0 0.2 2.2 2 0 0 2 2 2 0 KaiC Laminin_EGF PF00053.24 EGC35438.1 - 1.1 9.4 34.9 1.1 9.5 8.3 3.6 2 1 1 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC35439.1 - 6.6e-05 23.2 36.3 0.086 13.2 9.9 3.7 2 1 1 3 3 3 3 EGF-like domain LRR_1 PF00560.33 EGC35439.1 - 8 7.4 6.1 24 6.0 0.1 5.0 3 1 0 3 3 3 0 Leucine Rich Repeat Laminin_EGF PF00053.24 EGC35439.1 - 8.9 6.6 34.5 1.6 9.0 8.3 3.6 2 1 1 3 3 3 0 Laminin EGF domain Tetraspanin PF00335.20 EGC35440.1 - 1.1e-28 100.5 10.9 1.4e-28 100.2 10.9 1.1 1 0 0 1 1 1 1 Tetraspanin family TarH PF02203.15 EGC35440.1 - 0.067 13.1 7.5 0.47 10.3 1.1 2.6 2 1 0 2 2 2 0 Tar ligand binding domain homologue CcmH PF03918.14 EGC35440.1 - 0.25 10.6 1.5 0.43 9.9 0.2 2.1 1 1 0 2 2 2 0 Cytochrome C biogenesis protein AC_N PF16214.5 EGC35440.1 - 0.52 9.4 2.2 0.68 9.0 2.2 1.2 1 0 0 1 1 1 0 Adenylyl cyclase N-terminal extracellular and transmembrane region Wzy_C PF04932.15 EGC35440.1 - 7.9 6.1 12.8 1.7 8.3 0.5 2.9 3 0 0 3 3 3 0 O-Antigen ligase DUF4064 PF13273.6 EGC35440.1 - 8.1 6.8 18.9 21 5.5 0.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) Sec16_C PF12931.7 EGC35441.1 - 3e-11 43.5 1.5 8.3e-06 25.7 0.0 3.0 3 0 0 3 3 3 2 Sec23-binding domain of Sec16 WD40 PF00400.32 EGC35441.1 - 9.8e-10 38.9 13.4 0.0013 19.5 0.3 5.9 6 0 0 6 6 6 2 WD domain, G-beta repeat Prp18 PF02840.15 EGC35441.1 - 3.9e-06 27.0 0.1 3.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Prp18 domain ANAPC4_WD40 PF12894.7 EGC35441.1 - 2e-05 24.8 0.1 0.047 14.0 0.0 3.8 1 1 3 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain SRA1 PF07304.11 EGC35441.1 - 0.0013 18.6 0.0 0.0013 18.6 0.0 3.7 2 2 0 2 2 2 1 Steroid receptor RNA activator (SRA1) Nudix_hydro PF18290.1 EGC35441.1 - 0.097 12.7 0.6 7.8 6.6 0.1 2.6 2 0 0 2 2 2 0 Nudix hydrolase domain Crystall_3 PF08964.10 EGC35441.1 - 0.11 12.7 0.2 1.4 9.1 0.1 2.6 2 0 0 2 2 2 0 Beta/Gamma crystallin Ku_PK_bind PF08785.11 EGC35441.1 - 0.11 12.6 0.1 0.56 10.4 0.0 2.2 2 0 0 2 2 2 0 Ku C terminal domain like Uma2 PF05685.12 EGC35442.1 - 1.2e-06 28.2 0.0 1.7e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease MnmE_helical PF12631.7 EGC35443.1 - 5.9e-46 157.2 3.7 7.6e-46 156.9 3.7 1.1 1 0 0 1 1 1 1 MnmE helical domain TrmE_N PF10396.9 EGC35443.1 - 8e-37 126.1 0.0 2.9e-36 124.3 0.0 2.0 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.23 EGC35443.1 - 2.5e-21 75.9 0.2 6.5e-21 74.5 0.2 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC35443.1 - 1.2e-06 28.7 2.2 2.2e-05 24.6 2.1 2.5 1 1 0 1 1 1 1 Dynamin family FeoB_N PF02421.18 EGC35443.1 - 2.8e-06 26.9 0.3 6e-06 25.9 0.3 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC35443.1 - 0.0018 18.2 8.9 0.27 11.1 0.0 3.4 2 1 0 3 3 3 2 RsgA GTPase GTP_EFTU PF00009.27 EGC35443.1 - 0.0023 17.5 1.0 0.097 12.2 0.8 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_18 PF13238.6 EGC35443.1 - 0.0072 16.9 0.2 0.026 15.1 0.2 2.1 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC35443.1 - 0.0077 16.6 0.0 0.035 14.5 0.0 2.1 1 1 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.6 EGC35443.1 - 0.03 14.5 0.0 0.073 13.3 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC35443.1 - 0.054 13.8 0.3 0.67 10.2 0.1 2.8 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.27 EGC35443.1 - 0.15 12.6 5.5 0.36 11.4 4.8 2.0 1 1 0 1 1 1 0 ABC transporter Rep_2 PF01719.17 EGC35443.1 - 5.7 6.7 9.4 7.3 6.3 5.0 2.5 1 1 1 2 2 2 0 Plasmid replication protein MARVEL PF01284.23 EGC35444.1 - 0.00076 19.5 9.6 0.001 19.1 9.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain TarH PF02203.15 EGC35444.1 - 0.27 11.1 2.2 6.9 6.6 0.0 2.5 2 1 0 2 2 2 0 Tar ligand binding domain homologue DUF5373 PF17343.2 EGC35444.1 - 1.1 9.1 8.3 1.2 8.9 2.4 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5373) DUF898 PF05987.13 EGC35444.1 - 4.4 6.2 8.8 6.7 5.7 0.5 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) CLZ PF16526.5 EGC35445.1 - 0.088 13.2 1.8 3.4 8.1 0.1 2.8 2 1 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Spectrin PF00435.21 EGC35445.1 - 0.094 13.2 1.5 0.36 11.3 0.2 2.1 2 0 0 2 2 2 0 Spectrin repeat Siah-Interact_N PF09032.11 EGC35445.1 - 0.16 12.3 1.7 12 6.3 0.3 2.2 2 0 0 2 2 2 0 Siah interacting protein, N terminal Str_synth PF03088.16 EGC35446.1 - 4.8e-17 61.9 1.0 7.5e-15 54.8 0.0 3.5 2 1 1 3 3 3 1 Strictosidine synthase SGL PF08450.12 EGC35446.1 - 9.1e-13 48.4 0.0 3.3e-12 46.5 0.0 1.9 1 1 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Arylesterase PF01731.20 EGC35446.1 - 3e-05 24.1 1.3 0.00064 19.9 0.0 3.3 4 0 0 4 4 4 1 Arylesterase NHL PF01436.21 EGC35446.1 - 0.0017 18.3 3.7 0.21 11.7 0.1 4.5 6 0 0 6 6 6 1 NHL repeat ABC_tran PF00005.27 EGC35447.1 - 1.3e-54 184.5 0.8 2.5e-26 92.8 0.1 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.7 EGC35447.1 - 5e-40 137.7 50.2 1.7e-24 86.6 28.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.6 EGC35447.1 - 3.5e-19 69.7 1.0 3e-09 37.1 0.0 4.8 4 0 0 4 4 4 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC35447.1 - 1.1e-06 28.2 0.0 0.43 10.0 0.0 3.9 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC35447.1 - 0.00061 19.5 3.6 0.064 13.0 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC35447.1 - 0.0096 15.8 1.1 3 7.7 0.1 2.5 2 0 0 2 2 2 2 RsgA GTPase SbcCD_C PF13558.6 EGC35447.1 - 0.034 14.4 0.0 0.86 9.9 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Mg_chelatase PF01078.21 EGC35447.1 - 0.075 12.4 0.0 25 4.1 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI Zeta_toxin PF06414.12 EGC35447.1 - 0.11 11.7 0.2 8.3 5.6 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin SRP54 PF00448.22 EGC35447.1 - 0.26 10.9 1.4 16 5.0 0.1 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF2970 PF11174.8 EGC35447.1 - 1.6 8.7 4.8 6.3 6.7 4.8 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2970) DUF5389 PF17364.2 EGC35447.1 - 1.6 8.8 7.1 1.7 8.7 0.0 3.8 3 0 0 3 3 3 0 Family of unknown function (DUF5389) OSCP PF00213.18 EGC35448.1 - 1e-14 55.0 0.1 2.7e-14 53.6 0.0 1.6 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit DUF5024 PF16427.5 EGC35448.1 - 0.035 14.4 0.1 0.4 11.0 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF5024) CSF-1 PF05337.11 EGC35448.1 - 0.081 13.0 0.0 0.2 11.7 0.0 1.6 1 0 0 1 1 1 0 Macrophage colony stimulating factor-1 (CSF-1) DUF1298 PF06974.13 EGC35450.1 - 0.084 12.8 0.0 0.19 11.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1298) FNIP PF05725.12 EGC35451.1 - 2.6e-24 85.1 20.9 2e-06 27.9 1.3 4.9 2 1 4 6 6 6 6 FNIP Repeat Serinc PF03348.15 EGC35452.1 - 9.8e-118 393.8 20.5 1.2e-117 393.5 20.5 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MFAP1 PF06991.11 EGC35453.1 - 1.6e-30 106.6 5.4 1.6e-30 106.6 5.4 2.5 2 1 0 2 2 2 1 Microfibril-associated/Pre-mRNA processing Profilin PF00235.19 EGC35454.1 - 4.4e-08 33.4 0.1 6.7e-08 32.9 0.1 1.4 1 1 0 1 1 1 1 Profilin STAS PF01740.21 EGC35454.1 - 0.036 13.7 0.0 0.066 12.9 0.0 1.4 1 0 0 1 1 1 0 STAS domain Med2 PF11214.8 EGC35454.1 - 0.13 12.4 2.4 2.9 8.1 0.3 2.2 2 0 0 2 2 2 0 Mediator complex subunit 2 DUF1084 PF06454.11 EGC35455.1 - 4.9e-10 39.2 30.2 4.9e-09 36.0 30.2 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) Jun PF03957.13 EGC35457.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Jun PF03957.13 EGC35458.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Jun PF03957.13 EGC35459.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Jun PF03957.13 EGC35460.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Jun PF03957.13 EGC35461.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor Jun PF03957.13 EGC35462.1 - 0.034 14.1 0.4 0.036 13.9 0.4 1.0 1 0 0 1 1 1 0 Jun-like transcription factor DUF726 PF05277.12 EGC35463.1 - 3.5e-67 226.7 1.9 3.5e-67 226.7 1.9 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF726) VPS9 PF02204.18 EGC35463.1 - 3.3e-13 49.7 2.0 1.3e-12 47.8 0.4 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain RNA_pol_Rpc4 PF05132.14 EGC35465.1 - 2.7e-23 83.0 0.1 2.7e-23 83.0 0.1 2.2 3 0 0 3 3 3 1 RNA polymerase III RPC4 Ras PF00071.22 EGC35467.1 - 1.5e-41 141.7 0.1 1.8e-41 141.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35467.1 - 3.4e-22 78.9 0.0 6.4e-22 78.0 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35467.1 - 5.8e-15 55.2 0.1 1.2e-14 54.1 0.1 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family SRPRB PF09439.10 EGC35467.1 - 9.3e-06 25.2 0.1 2.4e-05 23.9 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC35467.1 - 1.4e-05 24.6 0.4 1.7e-05 24.3 0.4 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PBECR3 PF18812.1 EGC35467.1 - 0.018 15.0 1.3 0.026 14.5 0.2 1.9 2 0 0 2 2 2 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease3 Adaptin_N PF01602.20 EGC35468.1 - 2.2e-70 237.7 29.2 3.7e-70 237.0 29.2 1.3 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.7 EGC35468.1 - 2.2e-08 34.3 0.1 2.2e-08 34.3 0.1 5.1 2 2 2 5 5 5 1 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGC35468.1 - 0.0007 20.1 1.0 0.31 11.7 0.2 2.8 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGC35468.1 - 0.0032 17.8 0.0 0.88 10.0 0.0 3.3 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.22 EGC35468.1 - 0.043 14.1 0.1 1.3 9.5 0.0 3.3 2 0 0 2 2 2 0 HEAT repeat RTP1_C1 PF10363.9 EGC35468.1 - 1.3 9.2 8.5 14 5.9 0.2 4.4 3 2 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 RIO1 PF01163.22 EGC35469.1 - 3.1e-76 255.2 0.7 3.1e-76 255.2 0.7 1.6 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGC35469.1 - 5.8e-05 22.0 0.0 5.8e-05 22.0 0.0 1.9 2 0 0 2 2 2 1 Fungal protein kinase TetR_C_2 PF08361.11 EGC35469.1 - 0.034 14.3 0.8 1.3 9.2 0.1 2.5 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region YL1 PF05764.13 EGC35469.1 - 0.035 14.2 19.6 0.068 13.3 19.6 1.5 1 0 0 1 1 1 0 YL1 nuclear protein CDC45 PF02724.14 EGC35469.1 - 0.15 10.3 17.5 0.22 9.7 17.5 1.4 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.12 EGC35469.1 - 0.16 11.7 20.6 0.3 10.8 20.6 1.5 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SGT1 PF07093.11 EGC35469.1 - 0.22 10.0 14.1 0.28 9.6 14.1 1.3 1 0 0 1 1 1 0 SGT1 protein Dynactin PF12455.8 EGC35470.1 - 5.9e-36 124.2 10.4 5.9e-36 124.2 10.4 5.5 5 1 0 6 6 6 1 Dynein associated protein CAP_GLY PF01302.25 EGC35470.1 - 2.5e-22 78.7 0.1 3.9e-22 78.0 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ras PF00071.22 EGC35471.1 - 1.2e-57 194.1 0.0 1.4e-57 193.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35471.1 - 9.7e-20 71.0 0.0 1.9e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35471.1 - 2.4e-12 46.7 0.0 3e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC35471.1 - 0.0014 18.2 0.0 0.0042 16.7 0.0 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Voldacs PF03517.13 EGC35471.1 - 0.0031 17.7 0.4 0.0042 17.2 0.4 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Septin PF00735.18 EGC35471.1 - 0.013 14.8 0.9 0.21 10.8 0.0 2.6 2 1 1 3 3 3 0 Septin AAA_16 PF13191.6 EGC35471.1 - 0.019 15.4 0.0 0.027 14.8 0.0 1.5 1 1 0 1 1 1 0 AAA ATPase domain DUF4611 PF15387.6 EGC35471.1 - 0.039 14.2 1.9 0.07 13.3 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RsgA_GTPase PF03193.16 EGC35471.1 - 0.045 13.6 0.0 4.4 7.2 0.0 2.3 2 0 0 2 2 2 0 RsgA GTPase STIL_N PF15253.6 EGC35471.1 - 0.075 12.0 1.5 0.094 11.6 1.5 1.1 1 0 0 1 1 1 0 SCL-interrupting locus protein N-terminus AAA_22 PF13401.6 EGC35471.1 - 0.078 13.3 0.1 0.85 9.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain FeoB_N PF02421.18 EGC35471.1 - 0.084 12.4 0.0 0.22 11.1 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B Presenilin PF01080.17 EGC35471.1 - 0.44 9.3 1.1 0.52 9.0 1.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4298 PF14131.6 EGC35473.1 - 0.022 14.7 1.9 0.036 14.0 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4298) Pox_E10 PF04805.12 EGC35473.1 - 0.045 13.6 1.2 0.084 12.7 1.2 1.4 1 0 0 1 1 1 0 E10-like protein conserved region PH PF00169.29 EGC35474.1 - 6.3e-28 97.4 3.7 9.3e-13 48.6 0.2 3.0 2 0 0 2 2 2 2 PH domain Yop-YscD_cpl PF16697.5 EGC35474.1 - 7.5e-19 67.8 0.2 7.1e-18 64.7 0.0 2.6 3 0 0 3 3 3 1 Inner membrane component of T3SS, cytoplasmic domain FHA PF00498.26 EGC35474.1 - 5.1e-17 62.0 4.3 9.7e-17 61.1 1.2 2.9 3 0 0 3 3 3 1 FHA domain PH_8 PF15409.6 EGC35474.1 - 5.7e-09 36.1 2.8 0.00018 21.7 1.4 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.6 EGC35474.1 - 3.8e-07 30.5 17.5 2.9e-05 24.4 1.3 4.6 3 3 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.6 EGC35474.1 - 0.00028 21.2 1.1 3.4 8.0 0.0 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.6 EGC35474.1 - 0.00071 19.7 4.8 0.16 12.1 0.7 2.8 2 1 0 2 2 2 2 PH domain S10_plectin PF03501.15 EGC35474.1 - 0.076 13.1 0.4 15 5.8 0.0 2.6 2 0 0 2 2 2 0 Plectin/S10 domain DSHCT PF08148.12 EGC35475.1 - 6.8e-50 168.9 0.2 1.7e-49 167.6 0.2 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.6 EGC35475.1 - 1.6e-39 136.4 7.0 1.6e-39 136.4 7.0 2.0 2 0 0 2 2 2 1 rRNA-processing arch domain DEAD PF00270.29 EGC35475.1 - 8.5e-17 61.5 0.1 3.9e-16 59.3 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Ski2_N PF17911.1 EGC35475.1 - 1.3e-13 51.0 0.0 6.7e-13 48.6 0.0 2.2 2 0 0 2 2 2 1 Ski2 N-terminal region Helicase_C PF00271.31 EGC35475.1 - 4e-06 27.1 1.1 6e-05 23.4 0.1 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGC35475.1 - 0.0053 17.0 0.1 0.18 12.0 0.0 3.0 3 0 0 3 3 3 1 AAA domain Beta-lactamase PF00144.24 EGC35476.1 - 1.3e-30 106.8 0.0 1.6e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.20 EGC35476.1 - 0.025 14.0 0.0 0.052 13.0 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase HECW_N PF16562.5 EGC35476.1 - 0.19 11.5 1.4 0.35 10.7 0.5 1.9 2 0 0 2 2 2 0 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 FNIP PF05725.12 EGC35477.1 - 7.4e-52 173.3 71.7 2.3e-10 40.5 3.0 13.5 9 2 2 13 13 13 11 FNIP Repeat zf-B_box PF00643.24 EGC35477.1 - 4.1e-08 33.3 4.4 8.8e-08 32.2 4.4 1.5 1 0 0 1 1 1 1 B-box zinc finger DRE2_N PF16803.5 EGC35477.1 - 0.13 12.5 2.0 0.33 11.2 2.0 1.6 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Abhydro_lipase PF04083.16 EGC35478.1 - 1.4e-18 66.2 1.6 4.7e-18 64.5 1.6 1.9 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.20 EGC35478.1 - 1.4e-14 54.4 1.9 2.1e-14 53.8 0.2 2.2 2 1 0 2 2 2 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC35478.1 - 0.063 12.5 0.0 0.13 11.5 0.0 1.5 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Inhibitor_I71 PF12628.7 EGC35478.1 - 0.096 12.5 2.6 0.17 11.7 2.6 1.3 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor Pap_E4 PF02711.14 EGC35478.1 - 0.21 12.6 3.8 0.35 11.8 3.8 1.4 1 0 0 1 1 1 0 E4 protein DUF5423 PF17461.2 EGC35478.1 - 2 7.2 6.9 3.2 6.5 6.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5423) THF_DHG_CYH PF00763.23 EGC35479.1 - 2.6e-20 72.8 0.0 4.6e-20 72.0 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.19 EGC35479.1 - 3.4e-15 55.7 0.7 9.7e-13 47.7 0.7 3.1 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain DpaA_N PF16924.5 EGC35479.1 - 0.00046 20.2 0.0 0.0024 17.9 0.0 2.1 2 0 0 2 2 2 1 Dipicolinate synthase subunit A N-terminal domain ArsB PF02040.15 EGC35479.1 - 0.064 12.6 0.0 0.1 11.9 0.0 1.2 1 0 0 1 1 1 0 Arsenical pump membrane protein Urocanase PF01175.18 EGC35480.1 - 1.2e-89 299.5 0.0 1.8e-89 298.9 0.0 1.3 1 0 0 1 1 1 1 Urocanase Rossmann-like domain Urocanase_C PF17392.2 EGC35480.1 - 4.4e-86 287.3 1.1 6.7e-86 286.7 1.1 1.3 1 0 0 1 1 1 1 Urocanase C-terminal domain Urocanase_N PF17391.2 EGC35480.1 - 1.8e-55 186.1 0.6 3.4e-55 185.2 0.6 1.5 1 0 0 1 1 1 1 Urocanase N-terminal domain ETC_C1_NDUFA4 PF04800.12 EGC35481.1 - 1.1e-26 92.9 0.0 1.6e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region SET PF00856.28 EGC35483.1 - 4.8e-15 56.3 0.7 7.6e-15 55.7 0.7 1.3 1 0 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGC35483.1 - 0.0016 18.4 11.5 0.0016 18.4 11.5 3.4 3 0 0 3 3 3 1 MYND finger zinc_ribbon_12 PF11331.8 EGC35483.1 - 0.11 12.3 8.1 0.25 11.2 4.3 3.0 3 0 0 3 3 3 0 Probable zinc-ribbon domain Desulfoferrod_N PF06397.12 EGC35483.1 - 0.55 9.9 8.3 2.2 8.0 1.0 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain Rad51 PF08423.11 EGC35484.1 - 5.5e-37 127.4 0.6 6.4e-19 68.2 0.0 2.2 1 1 1 2 2 2 2 Rad51 HHH_5 PF14520.6 EGC35484.1 - 4.2e-08 33.7 2.6 6.3e-08 33.1 1.2 1.9 2 0 0 2 2 2 1 Helix-hairpin-helix domain Coatomer_E PF04733.14 EGC35484.1 - 0.0025 17.3 0.4 0.0032 16.9 0.4 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit HHH PF00633.23 EGC35484.1 - 0.022 14.6 0.0 0.06 13.3 0.0 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix motif ATPase PF06745.13 EGC35484.1 - 0.087 12.2 0.5 0.087 12.2 0.5 1.7 2 0 0 2 2 2 0 KaiC Sigma70_ner PF04546.13 EGC35484.1 - 0.19 11.6 5.4 0.26 11.2 5.4 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Pur_DNA_glyco PF02245.16 EGC35485.1 - 0.0068 15.9 0.0 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) DUF3430 PF11912.8 EGC35486.1 - 1.9e-14 54.2 23.2 2.2e-14 54.0 23.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) zf-RING_13 PF17977.1 EGC35486.1 - 0.039 14.1 0.1 0.11 12.7 0.1 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain EB PF01683.18 EGC35486.1 - 1.2 9.5 8.2 0.8 10.0 1.6 2.9 2 1 0 2 2 2 0 EB module zf-CCHC PF00098.23 EGC35487.1 - 0.0027 17.7 20.2 0.025 14.6 2.2 3.6 3 1 0 3 3 3 2 Zinc knuckle zf-CCHC_4 PF14392.6 EGC35487.1 - 0.4 10.5 12.5 2.4 8.0 1.5 2.6 1 1 1 2 2 2 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGC35487.1 - 2.1 8.2 23.5 0.074 12.9 5.1 2.8 3 0 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.6 EGC35487.1 - 2.8 8.0 17.8 0.11 12.4 0.7 3.5 1 1 2 3 3 3 0 Zinc knuckle LNS2 PF08235.13 EGC35488.1 - 1.2e-98 329.1 0.2 1.9e-98 328.5 0.2 1.3 1 0 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.14 EGC35488.1 - 1.5e-37 127.6 0.0 4.2e-37 126.2 0.0 1.8 1 0 0 1 1 1 1 lipin, N-terminal conserved region Lipin_mid PF16876.5 EGC35488.1 - 8.4e-20 70.8 0.1 8.4e-20 70.8 0.1 2.4 3 0 0 3 3 3 1 Lipin/Ned1/Smp2 multi-domain protein middle domain DUF3488 PF11992.8 EGC35488.1 - 0.086 11.8 0.7 0.13 11.2 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Pex14_N PF04695.13 EGC35488.1 - 1.3 9.7 16.1 0.26 11.9 8.1 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Asparaginase PF00710.20 EGC35489.1 - 1.2e-65 220.6 0.0 5.7e-65 218.5 0.0 1.9 2 0 0 2 2 2 1 Asparaginase, N-terminal Asparaginase_C PF17763.1 EGC35489.1 - 8.4e-32 109.8 0.1 1.5e-31 109.0 0.1 1.4 1 0 0 1 1 1 1 Glutaminase/Asparaginase C-terminal domain EF-hand_1 PF00036.32 EGC35490.1 - 7.8e-15 53.2 4.9 2.2e-07 30.0 0.1 3.5 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.6 EGC35490.1 - 1.2e-13 51.3 0.1 3.9e-13 49.6 0.1 2.0 1 0 0 1 1 1 1 EF-hand domain pair WWE PF02825.20 EGC35490.1 - 4.2e-13 49.7 1.0 1.2e-12 48.2 1.0 1.9 1 0 0 1 1 1 1 WWE domain EF-hand_6 PF13405.6 EGC35490.1 - 5.5e-12 44.6 1.9 3.3e-06 26.6 0.1 3.6 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.6 EGC35490.1 - 5.9e-11 42.0 1.1 1.3e-05 25.0 0.0 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC35490.1 - 1.9e-10 39.8 0.4 2.4e-06 26.8 0.1 2.7 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.6 EGC35490.1 - 2.9e-05 24.3 0.0 6.2e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.9 EGC35490.1 - 6.8e-05 23.2 0.1 0.00026 21.3 0.0 2.0 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region CDC45 PF02724.14 EGC35490.1 - 0.94 7.7 4.6 1.6 6.9 4.6 1.3 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGC35490.1 - 1.2 9.5 4.8 3.4 8.1 4.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4598 PF15370.6 EGC35490.1 - 6.5 7.3 11.7 0.36 11.3 5.8 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4598) Cdh1_DBD_1 PF18196.1 EGC35490.1 - 7.6 6.9 9.7 3.9 7.8 3.8 2.4 2 0 0 2 2 2 0 Chromodomain helicase DNA-binding domain 1 GST_C PF00043.25 EGC35491.1 - 1.6e-12 47.4 0.0 2.8e-12 46.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC35491.1 - 3.4e-11 43.4 0.0 6.3e-11 42.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC35491.1 - 4.6e-11 42.6 0.0 7.4e-11 41.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC35491.1 - 4.2e-10 39.8 0.1 1.3e-09 38.3 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC35491.1 - 3.5e-09 36.8 0.1 7.2e-09 35.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC35491.1 - 1.5e-08 34.8 0.0 3.6e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_4 PF17172.4 EGC35491.1 - 0.0078 16.9 0.1 0.039 14.7 0.1 2.0 1 1 0 1 1 1 1 Glutathione S-transferase N-terminal domain Hydrolase_4 PF12146.8 EGC35492.1 - 2.8e-13 49.7 0.2 2.5e-12 46.6 0.2 2.0 1 1 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC35492.1 - 2.1e-07 31.8 0.0 2.9e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGC35492.1 - 4.9e-07 29.4 0.1 0.0015 18.0 0.1 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGC35492.1 - 3.2e-06 27.0 0.6 0.029 14.0 0.0 2.3 1 1 0 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_2 PF02230.16 EGC35492.1 - 0.00034 20.5 0.1 0.058 13.2 0.1 2.6 3 0 0 3 3 3 1 Phospholipase/Carboxylesterase AXE1 PF05448.12 EGC35492.1 - 0.0016 17.2 0.2 0.88 8.2 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.18 EGC35492.1 - 0.023 14.3 0.1 0.58 9.7 0.0 2.1 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Lipase_2 PF01674.18 EGC35492.1 - 0.033 13.7 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 2) DLH PF01738.18 EGC35492.1 - 0.055 13.0 0.1 3.3 7.2 0.0 2.2 2 0 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_4 PF08386.10 EGC35492.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 TAP-like protein Tannase PF07519.11 EGC35492.1 - 0.078 11.9 0.1 1.7 7.4 0.0 2.1 2 0 0 2 2 2 0 Tannase and feruloyl esterase Histone PF00125.24 EGC35493.1 - 2.3e-17 63.6 4.1 3.1e-09 37.3 1.0 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC35493.1 - 3.8e-09 36.7 1.2 7.4e-05 23.0 0.2 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TAFII28 PF04719.14 EGC35493.1 - 0.0002 21.4 0.5 0.45 10.7 0.1 2.2 2 0 0 2 2 2 2 hTAFII28-like protein conserved region TFIID_20kDa PF03847.13 EGC35493.1 - 0.00065 20.1 1.3 0.0097 16.4 0.1 2.3 2 1 0 2 2 2 1 Transcription initiation factor TFIID subunit A TFIID-31kDa PF02291.15 EGC35493.1 - 0.0048 17.0 0.3 0.055 13.6 0.1 2.0 2 0 0 2 2 2 1 Transcription initiation factor IID, 31kD subunit TAF PF02969.17 EGC35493.1 - 0.034 14.3 0.7 4.3 7.6 0.1 2.5 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.16 EGC35493.1 - 0.058 13.4 0.9 0.3 11.1 0.1 2.1 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit UQ_con PF00179.26 EGC35494.1 - 4.4e-36 123.6 0.0 4.9e-36 123.5 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGC35494.1 - 0.00061 19.5 0.0 0.00066 19.4 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGC35494.1 - 0.033 14.5 0.1 0.05 13.9 0.1 1.4 1 1 0 1 1 1 0 RWD domain Glyco_transf_49 PF13896.6 EGC35495.1 - 2.4e-51 175.0 0.7 1.1e-41 143.3 0.1 2.2 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Coiled PF05710.12 EGC35495.1 - 4.8e-19 69.0 23.0 4.8e-19 69.0 23.0 1.9 2 0 0 2 2 2 1 Coiled coil Glycos_transf_2 PF00535.26 EGC35495.1 - 0.027 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 Glycosyl transferase family 2 IPK PF03770.16 EGC35496.1 - 8.8e-38 130.1 1.8 9.1e-38 130.1 0.2 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase Sir1 PF11603.8 EGC35496.1 - 0.028 14.9 2.7 1.4 9.4 0.6 2.5 2 0 0 2 2 2 0 Regulatory protein Sir1 Dehydratase_SU PF02287.15 EGC35496.1 - 0.037 14.1 0.1 0.6 10.2 0.0 2.2 2 0 0 2 2 2 0 Dehydratase small subunit 7tm_3 PF00003.22 EGC35497.1 - 2.2e-44 152.0 22.4 2.2e-44 152.0 22.4 1.5 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC35497.1 - 3.7e-19 68.8 1.8 3.7e-19 68.8 1.8 1.7 2 0 0 2 2 2 1 ABC transporter substrate-binding protein PnrA-like TraS PF10624.9 EGC35497.1 - 2.9 7.8 7.9 6.4 6.7 0.7 3.0 1 1 1 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS 7tm_3 PF00003.22 EGC35498.1 - 3.4e-45 154.6 21.5 5.5e-45 153.9 21.5 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.14 EGC35498.1 - 3.4e-17 62.4 3.8 3.4e-17 62.4 3.8 1.8 2 0 0 2 2 2 1 ABC transporter substrate-binding protein PnrA-like SLC12 PF03522.15 EGC35498.1 - 5.6 5.9 11.8 8.6 5.3 11.8 1.3 1 0 0 1 1 1 0 Solute carrier family 12 NIF PF03031.18 EGC35499.1 - 1.1e-29 103.2 1.3 1.1e-29 103.2 1.3 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGC35499.1 - 4.2e-12 46.3 0.0 2.2e-11 43.9 0.0 2.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGC35499.1 - 4.8e-09 36.0 0.0 1.4e-08 34.6 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EGC35499.1 - 6.3e-06 26.4 0.3 4.3e-05 23.7 0.1 2.6 1 1 1 2 2 2 1 DNA ligase 3 BRCT domain BRCT_2 PF16589.5 EGC35499.1 - 2.1e-05 24.9 0.3 0.00069 20.0 0.0 3.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain MPM1 PF17234.2 EGC35499.1 - 0.012 15.9 10.6 0.012 15.9 10.6 3.4 2 1 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 SOG2 PF10428.9 EGC35499.1 - 0.17 11.1 27.0 1 8.5 10.4 2.2 2 0 0 2 2 2 0 RAM signalling pathway protein Macoilin PF09726.9 EGC35499.1 - 0.19 10.2 38.9 0.07 11.7 7.6 2.2 2 0 0 2 2 2 0 Macoilin family Peptidase_S49_N PF08496.10 EGC35499.1 - 4.6 7.3 9.3 14 5.7 9.3 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Apt1 PF10351.9 EGC35499.1 - 7.1 5.4 38.1 0.27 10.1 8.2 2.2 2 0 0 2 2 2 0 Golgi-body localisation protein domain Coiled PF05710.12 EGC35500.1 - 4.8e-22 78.6 21.0 5.4e-22 78.4 21.0 1.0 1 0 0 1 1 1 1 Coiled coil Sclerostin PF05463.11 EGC35500.1 - 0.12 12.1 0.2 0.15 11.8 0.2 1.1 1 0 0 1 1 1 0 Sclerostin (SOST) DUF4211 PF13926.6 EGC35501.1 - 1.7e-26 93.0 2.7 1.7e-26 93.0 2.7 3.9 3 0 0 3 3 3 1 Domain of unknown function (DUF4211) SH3_9 PF14604.6 EGC35502.1 - 2.1e-26 91.5 1.7 1.1e-12 47.6 0.5 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.28 EGC35502.1 - 2.1e-22 78.5 1.3 1.1e-13 50.5 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.17 EGC35502.1 - 1.4e-20 72.7 0.3 8.2e-11 41.4 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.23 EGC35502.1 - 6.3e-09 36.0 0.5 2.2e-08 34.2 0.5 2.0 1 0 0 1 1 1 1 Fes/CIP4, and EFC/F-BAR homology domain Pro_3_hydrox_C PF05373.11 EGC35502.1 - 0.009 16.1 0.2 0.025 14.6 0.2 1.8 1 0 0 1 1 1 1 L-proline 3-hydroxylase, C-terminal FRB_dom PF08771.11 EGC35502.1 - 1.1 9.8 5.3 1.4 9.4 3.3 2.3 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain TMEM214 PF10151.9 EGC35502.1 - 1.9 6.8 9.1 3.3 6.1 9.1 1.3 1 0 0 1 1 1 0 TMEM214, C-terminal, caspase 4 activator DUF421 PF04239.12 EGC35502.1 - 2.7 7.8 6.2 1.6 8.5 0.8 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF421) DUF4407 PF14362.6 EGC35502.1 - 2.8 7.2 8.8 4.2 6.6 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DIT1_PvcA PF05141.12 EGC35502.1 - 6.3 6.2 9.2 11 5.4 8.8 1.5 1 1 0 1 1 1 0 Pyoverdine/dityrosine biosynthesis protein PEPCK_ATP PF01293.20 EGC35503.1 - 1e-221 736.6 0.0 1.2e-221 736.4 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.6 EGC35503.1 - 0.0015 18.7 0.0 0.0025 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF4914 PF16260.5 EGC35503.1 - 0.0041 15.3 0.0 0.0068 14.6 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4914) AAA_16 PF13191.6 EGC35503.1 - 0.02 15.3 0.0 0.046 14.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Toxin_5 PF05294.13 EGC35504.1 - 3.5 8.1 7.0 7.6 7.0 7.0 1.6 1 0 0 1 1 1 0 Scorpion short toxin EGF_2 PF07974.13 EGC35504.1 - 6.9 7.1 12.7 16 6.0 12.7 1.6 1 0 0 1 1 1 0 EGF-like domain p450 PF00067.22 EGC35505.1 - 6.2e-100 335.1 0.0 7.2e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transposon_TraM PF12508.8 EGC35505.1 - 0.11 12.1 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Conjugative transposon, TraM UCR_hinge PF02320.16 EGC35506.1 - 2.1e-17 63.1 2.8 2.6e-17 62.8 2.8 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein UPF0203 PF05254.12 EGC35506.1 - 0.13 12.5 7.4 2.9 8.2 3.3 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) CHCH PF06747.13 EGC35506.1 - 0.55 10.4 5.9 4.5 7.5 0.3 2.5 2 0 0 2 2 2 0 CHCH domain DUF1168 PF06658.12 EGC35507.1 - 1.6e-29 102.4 26.8 2.4e-29 101.9 26.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) TFIIA PF03153.13 EGC35507.1 - 0.64 10.0 21.1 0.66 9.9 21.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF2368 PF10166.9 EGC35507.1 - 1.3 8.7 7.0 1.9 8.1 7.0 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) CNDH2_C PF16858.5 EGC35507.1 - 1.5 8.6 23.4 1.8 8.3 23.4 1.1 1 0 0 1 1 1 0 Condensin II complex subunit CAP-H2 or CNDH2, C-term Noggin PF05806.12 EGC35507.1 - 3.7 7.4 7.5 4.5 7.1 7.5 1.3 1 0 0 1 1 1 0 Noggin Fumarate_red_D PF02313.17 EGC35509.1 - 0.5 10.5 5.8 0.19 11.9 0.2 3.1 3 0 0 3 3 3 0 Fumarate reductase subunit D DUF4233 PF14017.6 EGC35509.1 - 0.66 10.3 4.2 1.8 8.9 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4233) dCMP_cyt_deam_1 PF00383.23 EGC35510.1 - 1.2e-14 54.0 0.1 2.1e-14 53.2 0.1 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGC35510.1 - 4.1e-08 33.1 0.1 5.9e-08 32.6 0.1 1.2 1 0 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGC35510.1 - 0.019 15.0 0.2 1.1 9.3 0.2 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase DUF2321 PF10083.9 EGC35510.1 - 0.063 12.9 0.5 0.11 12.1 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2321) zf-FPG_IleRS PF06827.14 EGC35510.1 - 0.31 11.0 1.9 11 6.0 0.3 2.5 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS RecR PF02132.15 EGC35510.1 - 0.4 10.3 3.0 6.7 6.4 0.0 2.5 2 0 0 2 2 2 0 RecR protein dCMP_cyt_deam_1 PF00383.23 EGC35511.1 - 1.4e-16 60.2 0.1 2.8e-16 59.2 0.1 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGC35511.1 - 5.6e-10 39.1 0.1 1.2e-09 38.0 0.1 1.6 1 1 0 1 1 1 1 MafB19-like deaminase Bd3614-deam PF14439.6 EGC35511.1 - 1.2e-05 25.4 1.2 0.00036 20.6 1.2 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase RVT_3 PF13456.6 EGC35511.1 - 0.029 14.2 0.1 0.045 13.6 0.1 1.3 1 0 0 1 1 1 0 Reverse transcriptase-like Antiterm PF03589.13 EGC35511.1 - 0.062 13.6 0.0 0.16 12.3 0.0 1.7 2 0 0 2 2 2 0 Antitermination protein Coiled PF05710.12 EGC35512.1 - 6.8e-22 78.1 16.7 7.7e-22 77.9 16.7 1.0 1 0 0 1 1 1 1 Coiled coil DUF4266 PF14086.6 EGC35512.1 - 4.1 8.4 12.4 10 7.1 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) USP7_ICP0_bdg PF12436.8 EGC35513.1 - 1.2e-32 113.1 0.1 3.2e-32 111.7 0.1 1.8 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 DUF3439 PF11921.8 EGC35513.1 - 0.019 14.9 11.3 0.043 13.8 11.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ubiquitin PF00240.23 EGC35513.1 - 0.023 14.4 0.0 0.52 10.1 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family Ubiquitin_2 PF14560.6 EGC35513.1 - 0.031 14.7 0.2 0.75 10.3 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin-like domain Mucin PF01456.17 EGC35513.1 - 1 9.3 21.1 1.9 8.5 21.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein UQ_con PF00179.26 EGC35514.1 - 2.9e-28 98.3 0.6 8.3e-26 90.3 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme CdvA PF18822.1 EGC35514.1 - 0.0037 17.1 8.6 0.0038 17.0 2.5 3.0 2 0 0 2 2 2 1 CdvA-like coiled-coil domain UEV PF05743.13 EGC35514.1 - 0.0093 15.8 0.1 0.051 13.4 0.0 2.3 3 0 0 3 3 3 1 UEV domain DUF1664 PF07889.12 EGC35514.1 - 0.011 15.8 4.8 0.52 10.4 1.0 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) DUF948 PF06103.11 EGC35514.1 - 0.03 14.6 5.4 4.8 7.5 0.0 3.8 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) VasL PF12486.8 EGC35514.1 - 0.042 13.7 0.2 0.042 13.7 0.2 2.2 2 0 0 2 2 2 0 Type VI secretion system, EvfB, or VasL Baculo_PEP_C PF04513.12 EGC35514.1 - 0.13 12.3 8.9 0.63 10.1 3.7 3.3 3 0 0 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus GIT_CC PF16559.5 EGC35514.1 - 0.51 10.2 6.5 2.3 8.1 1.4 3.1 3 0 0 3 3 3 0 GIT coiled-coil Rho guanine nucleotide exchange factor DNA_pol_phi PF04931.13 EGC35514.1 - 1.6 6.7 19.4 0.1 10.7 14.0 1.7 2 0 0 2 2 2 0 DNA polymerase phi TSNAXIP1_N PF15739.5 EGC35514.1 - 3.8 7.9 11.1 2.1 8.7 2.0 3.0 3 0 0 3 3 2 0 Translin-associated factor X-interacting N-terminus YlqD PF11068.8 EGC35514.1 - 4.7 7.6 15.3 2.3 8.6 0.3 3.6 4 0 0 4 4 4 0 YlqD protein CENP-F_leu_zip PF10473.9 EGC35515.1 - 1.2e-06 28.6 24.2 1.2e-06 28.6 24.2 10.7 1 1 8 9 9 9 3 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Fez1 PF06818.15 EGC35515.1 - 4.6e-05 24.0 66.6 0.00016 22.2 18.3 6.5 1 1 5 6 6 6 2 Fez1 Filament PF00038.21 EGC35515.1 - 0.0016 18.1 60.3 0.0016 18.1 60.3 5.7 1 1 4 5 5 5 3 Intermediate filament protein APG6_N PF17675.1 EGC35515.1 - 0.0031 18.0 26.1 0.0031 18.0 26.1 8.9 3 3 5 8 8 8 6 Apg6 coiled-coil region FliJ PF02050.16 EGC35515.1 - 0.0039 17.4 20.4 0.0039 17.4 20.4 8.0 4 2 3 8 8 8 2 Flagellar FliJ protein BST2 PF16716.5 EGC35515.1 - 0.0055 17.3 14.0 0.0055 17.3 14.0 11.5 3 3 9 13 13 13 3 Bone marrow stromal antigen 2 Atg14 PF10186.9 EGC35515.1 - 0.006 15.7 24.3 0.006 15.7 24.3 6.4 1 1 5 6 6 6 4 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2218 PF09981.9 EGC35515.1 - 1.5 9.3 7.1 2.5 8.6 0.0 4.3 4 1 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2218) Polyketide_cyc PF03364.20 EGC35516.1 - 5e-22 78.5 0.0 6.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Patatin PF01734.22 EGC35517.1 - 1.8e-14 54.4 1.3 5.7e-14 52.8 1.3 1.7 1 1 0 1 1 1 1 Patatin-like phospholipase DUF2470 PF10615.9 EGC35518.1 - 0.00078 20.0 0.0 0.0016 19.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Acyltransferase PF01553.21 EGC35520.1 - 4.1e-16 58.8 0.1 7.4e-16 58.0 0.1 1.4 1 0 0 1 1 1 1 Acyltransferase PROCN PF08083.11 EGC35521.1 - 2.1e-231 767.7 10.0 3.4e-231 767.1 10.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.8 EGC35521.1 - 8.5e-125 414.9 0.9 1.7e-124 413.9 0.9 1.5 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.9 EGC35521.1 - 4.2e-88 293.3 3.4 9.9e-88 292.1 3.4 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.11 EGC35521.1 - 2.1e-85 284.2 5.5 5.1e-85 283.0 5.5 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.9 EGC35521.1 - 4.5e-71 237.2 0.1 8.8e-71 236.2 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.11 EGC35521.1 - 1.5e-46 157.3 2.4 2.1e-46 156.8 1.2 1.9 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.9 EGC35521.1 - 8.2e-46 154.3 0.4 2.3e-45 152.8 0.4 1.9 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.21 EGC35521.1 - 1.2e-07 31.7 0.0 3.2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease PBP1_TM PF14812.6 EGC35522.1 - 0.37 11.2 3.4 1 9.8 3.4 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FNIP PF05725.12 EGC35523.1 - 1.2e-47 159.8 41.2 1.4e-11 44.3 2.2 7.8 4 2 5 9 9 9 9 FNIP Repeat FNIP PF05725.12 EGC35524.1 - 9.2e-53 176.2 44.3 1.5e-10 41.1 2.8 8.9 4 2 5 9 9 9 9 FNIP Repeat COMM_domain PF07258.14 EGC35525.1 - 1.1e-15 57.5 0.4 3e-15 56.1 0.0 1.9 2 0 0 2 2 2 1 COMM domain DUF5598 PF18127.1 EGC35525.1 - 0.11 12.9 0.5 1.1 9.8 0.0 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5598) PFK PF00365.20 EGC35526.1 - 2.8e-188 624.1 0.4 3.2e-104 348.2 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Myb_DNA-binding PF00249.31 EGC35527.1 - 9.4e-14 51.3 0.1 1.5e-13 50.7 0.1 1.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC35527.1 - 0.00052 20.2 0.3 0.00052 20.2 0.3 2.8 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF4746 PF15928.5 EGC35527.1 - 3.5 7.0 23.3 1.4 8.3 11.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) adh_short PF00106.25 EGC35528.1 - 2.7e-41 141.2 0.0 3.8e-41 140.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC35528.1 - 1e-29 103.8 0.0 1.3e-29 103.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC35528.1 - 1.9e-07 31.2 0.0 3.1e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC35528.1 - 0.002 17.6 0.0 0.0032 16.9 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.17 EGC35528.1 - 0.023 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain NAD_binding_10 PF13460.6 EGC35528.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding DUF478 PF04334.12 EGC35528.1 - 0.13 12.3 0.0 0.32 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF478) CLTH PF10607.9 EGC35530.1 - 4.9e-31 107.6 2.4 4.9e-31 107.6 2.4 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.6 EGC35530.1 - 2.1e-07 30.9 2.0 4e-07 29.9 2.0 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC35530.1 - 7.9e-06 25.7 1.4 1.4e-05 25.0 1.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC35530.1 - 6.9e-05 22.6 1.4 0.00013 21.8 1.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35530.1 - 0.00012 21.9 2.5 0.00025 20.8 2.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC35530.1 - 0.00018 21.6 0.9 0.00046 20.3 0.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.6 EGC35530.1 - 0.00037 20.7 1.7 0.00076 19.8 1.7 1.6 1 0 0 1 1 1 1 Ring finger domain Prok-RING_4 PF14447.6 EGC35530.1 - 0.015 15.1 2.4 0.042 13.7 2.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_2 PF13923.6 EGC35530.1 - 0.042 13.7 3.3 0.087 12.7 3.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FlaC_arch PF05377.11 EGC35530.1 - 0.9 10.0 4.6 7.1 7.1 0.8 2.9 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) FliD_N PF02465.18 EGC35530.1 - 0.92 10.2 5.4 1.6 9.4 2.5 2.3 2 0 0 2 2 2 0 Flagellar hook-associated protein 2 N-terminus BET PF17035.5 EGC35530.1 - 0.95 9.7 3.9 0.91 9.7 0.2 2.7 3 0 0 3 3 3 0 Bromodomain extra-terminal - transcription regulation Aminotran_1_2 PF00155.21 EGC35531.1 - 1.4e-46 159.3 0.0 1.8e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2232 PF09991.9 EGC35531.1 - 0.059 12.5 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) C2 PF00168.30 EGC35532.1 - 2e-19 69.8 0.0 4.6e-19 68.6 0.0 1.7 1 0 0 1 1 1 1 C2 domain Arrestin_C PF02752.22 EGC35532.1 - 7.3e-17 62.1 7.6 2.9e-16 60.1 0.5 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGC35532.1 - 4.7e-12 46.2 2.2 2.1e-08 34.4 0.4 3.6 2 2 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.30 EGC35532.1 - 0.002 18.5 0.2 0.0041 17.5 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) YhdB PF14148.6 EGC35532.1 - 0.067 13.3 0.2 0.2 11.8 0.2 1.8 1 0 0 1 1 1 0 YhdB-like protein LDB19 PF13002.7 EGC35532.1 - 0.11 12.2 1.9 0.45 10.2 0.0 2.7 3 1 0 3 3 3 0 Arrestin_N terminal like DUF2393 PF09624.10 EGC35532.1 - 3.7 7.5 8.5 0.64 10.0 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2393) zf-RING_2 PF13639.6 EGC35533.1 - 2.2e-08 34.3 10.8 4.4e-08 33.3 10.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC35533.1 - 9.4e-08 31.8 9.4 1.9e-07 30.8 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35533.1 - 3.7e-07 29.9 12.3 1e-06 28.5 12.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC35533.1 - 4.6e-07 29.6 8.9 8.2e-07 28.8 8.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC35533.1 - 8.2e-05 22.5 5.5 0.00026 20.9 5.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC35533.1 - 0.0008 19.6 9.8 0.0031 17.8 9.8 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC35533.1 - 0.0035 17.5 9.6 0.0076 16.4 9.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC35533.1 - 0.0037 17.2 10.4 0.0074 16.2 10.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC35533.1 - 0.023 14.5 8.1 0.059 13.2 8.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC35533.1 - 0.06 13.1 8.8 0.13 12.1 8.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zinc_ribbon_9 PF14369.6 EGC35533.1 - 0.23 11.8 4.5 0.64 10.3 4.5 1.8 1 0 0 1 1 1 0 zinc-ribbon DUF1272 PF06906.11 EGC35533.1 - 0.53 10.4 6.6 1 9.5 6.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 EGC35533.1 - 0.7 10.0 5.9 1.8 8.7 5.9 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_11 PF17123.5 EGC35533.1 - 1.6 8.6 7.2 3.4 7.5 7.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger Tcf25 PF04910.14 EGC35534.1 - 7.8e-82 275.2 7.6 1.4e-81 274.3 7.6 1.4 1 0 0 1 1 1 1 Transcriptional repressor TCF25 TFIIE-A_C PF11521.8 EGC35534.1 - 0.032 14.5 0.1 0.032 14.5 0.1 5.2 4 1 2 6 6 6 0 C-terminal general transcription factor TFIIE alpha Nucleoside_tran PF01733.18 EGC35534.1 - 6.1 6.1 7.7 0.45 9.8 0.8 2.2 2 0 0 2 2 2 0 Nucleoside transporter Syja_N PF02383.18 EGC35535.1 - 4e-82 276.1 4.1 4e-82 276.1 4.1 1.9 2 0 0 2 2 2 1 SacI homology domain hSac2 PF12456.8 EGC35535.1 - 1.7e-28 98.7 0.1 4.2e-28 97.4 0.1 1.7 1 0 0 1 1 1 1 Inositol phosphatase Acetyltransf_2 PF00797.17 EGC35538.1 - 1.5e-32 113.3 0.1 3.5e-32 112.1 0.1 1.5 1 1 0 1 1 1 1 N-acetyltransferase LisH PF08513.11 EGC35538.1 - 0.075 13.0 0.1 0.075 13.0 0.1 2.1 2 0 0 2 2 2 0 LisH RCC1_2 PF13540.6 EGC35539.1 - 9.1e-31 105.0 6.3 3.8e-09 36.1 0.0 6.9 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGC35539.1 - 1.1e-28 99.5 6.8 1.1e-08 35.6 0.1 6.4 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat OTU PF02338.19 EGC35540.1 - 3e-12 47.1 0.1 6.1e-12 46.1 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 EGC35540.1 - 0.061 13.3 38.0 0.11 12.5 38.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit OTU PF02338.19 EGC35541.1 - 4.1e-12 46.7 0.1 9.8e-12 45.5 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease LANC_like PF05147.13 EGC35543.1 - 0.038 12.6 0.1 0.048 12.2 0.1 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein FKBP_C PF00254.28 EGC35544.1 - 2.2e-30 104.8 0.1 2.7e-30 104.5 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4590 PF15257.6 EGC35544.1 - 0.019 14.9 0.0 0.027 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) HGTP_anticodon PF03129.20 EGC35544.1 - 0.063 13.4 0.0 0.081 13.1 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain Exo_endo_phos PF03372.23 EGC35545.1 - 1.7e-13 50.7 0.1 2.4e-13 50.1 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Head_binding PF09008.10 EGC35545.1 - 0.028 14.7 0.5 0.19 12.0 0.3 2.2 2 0 0 2 2 2 0 Head binding LIM PF00412.22 EGC35546.1 - 1.3e-37 127.8 52.8 3.6e-13 49.5 5.7 5.4 5 1 0 5 5 5 4 LIM domain AMP-binding PF00501.28 EGC35547.1 - 7.4e-107 357.6 0.0 9.6e-107 357.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC35547.1 - 0.00073 20.5 0.0 0.0015 19.4 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain EcKinase PF02958.20 EGC35548.1 - 2.4e-14 53.4 2.2 3.8e-10 39.5 0.1 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.23 EGC35548.1 - 0.00011 22.2 0.0 0.00016 21.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family SNF2_N PF00176.23 EGC35551.1 - 2.9e-70 236.7 0.0 2.9e-70 236.7 0.0 2.4 2 1 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC35551.1 - 1.7e-20 73.4 1.0 7.8e-19 68.1 0.0 3.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Bromodomain PF00439.25 EGC35551.1 - 1.2e-18 66.9 0.6 1.2e-18 66.9 0.6 3.2 3 0 0 3 3 3 1 Bromodomain HSA PF07529.13 EGC35551.1 - 2.1e-13 50.4 16.1 1.2e-12 47.9 16.1 2.5 1 0 0 1 1 1 1 HSA ResIII PF04851.15 EGC35551.1 - 1.2e-10 41.6 0.0 1.2e-10 41.6 0.0 3.7 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit NST1 PF13945.6 EGC35552.1 - 4.5 7.3 12.8 5 7.2 12.8 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator SapB_2 PF03489.17 EGC35553.1 - 8.9e-05 22.5 0.2 0.00017 21.7 0.2 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC35553.1 - 0.015 15.3 2.6 0.046 13.7 0.8 2.6 2 1 0 2 2 2 0 Saposin-like type B, region 1 DUF5332 PF17266.2 EGC35553.1 - 0.12 12.0 3.0 0.19 11.4 0.5 2.2 1 1 1 2 2 2 0 Family of unknown function (DUF5332) Peptidase_S8 PF00082.22 EGC35554.1 - 6.2e-43 147.1 0.7 6.2e-43 147.1 0.7 2.0 2 1 0 2 2 2 1 Subtilase family ABC2_membrane_3 PF12698.7 EGC35554.1 - 5.1 6.1 18.8 11 5.1 18.8 1.5 1 0 0 1 1 1 0 ABC-2 family transporter protein Mito_carr PF00153.27 EGC35555.1 - 1.3e-08 34.7 3.4 0.006 16.5 2.4 3.9 3 1 0 3 3 3 2 Mitochondrial carrier protein DnaJ PF00226.31 EGC35555.1 - 2.2e-05 24.5 3.2 6.2e-05 23.0 3.2 1.9 1 0 0 1 1 1 1 DnaJ domain SHE3 PF17078.5 EGC35555.1 - 0.0063 16.3 6.2 0.0097 15.6 6.2 1.2 1 0 0 1 1 1 1 SWI5-dependent HO expression protein 3 DUF438 PF04282.13 EGC35555.1 - 0.014 15.3 1.7 0.033 14.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF438) Peroxin-22 PF12827.7 EGC35555.1 - 0.027 14.4 0.7 0.06 13.3 0.2 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family SUIM_assoc PF16619.5 EGC35555.1 - 0.063 13.3 4.6 0.12 12.5 4.6 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF1910 PF08928.10 EGC35555.1 - 0.23 11.5 5.9 17 5.5 1.0 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF1910) Coat_F PF07875.12 EGC35555.1 - 8.6 6.7 10.3 1.4 9.2 6.0 1.9 2 0 0 2 2 2 0 Coat F domain DnaJ PF00226.31 EGC35556.1 - 1.1e-07 31.8 4.4 2.2e-07 30.9 4.4 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 EGC35556.1 - 0.0002 21.2 2.7 0.03 14.2 0.0 3.3 4 0 0 4 4 4 2 Mitochondrial carrier protein LRR_8 PF13855.6 EGC35556.1 - 0.034 13.9 2.4 0.72 9.7 0.3 2.5 2 0 0 2 2 2 0 Leucine rich repeat FNIP PF05725.12 EGC35557.1 - 1.7e-18 66.5 10.1 5.7e-11 42.4 3.0 2.0 2 0 0 2 2 2 2 FNIP Repeat Ipi1_N PF12333.8 EGC35558.1 - 3.8e-16 59.5 6.1 2.1e-15 57.2 0.9 3.8 3 1 0 3 3 3 1 Rix1 complex component involved in 60S ribosome maturation PilJ_C PF18223.1 EGC35560.1 - 0.024 15.1 0.3 0.072 13.6 0.1 1.9 2 0 0 2 2 2 0 Pili PilJ C-terminal domain FA_desaturase PF00487.24 EGC35561.1 - 1.4e-32 113.5 12.7 1.4e-32 113.5 12.7 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGC35561.1 - 3e-22 78.5 0.3 1.4e-21 76.4 0.0 2.3 3 0 0 3 3 3 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 EGC35561.1 - 0.0046 17.1 0.2 0.011 15.9 0.2 1.6 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone tRNA-synt_1b PF00579.25 EGC35562.1 - 5.1e-24 85.1 0.1 1.3e-23 83.8 0.0 1.7 2 1 0 2 2 2 1 tRNA synthetases class I (W and Y) HsdM_N PF12161.8 EGC35562.1 - 0.12 13.0 0.3 22 5.7 0.1 2.4 2 0 0 2 2 2 0 HsdM N-terminal domain MIF4G_like_2 PF09090.11 EGC35563.1 - 5.8e-32 111.2 9.0 1.5e-31 109.9 9.0 1.7 1 0 0 1 1 1 1 MIF4G like MIF4G_like PF09088.11 EGC35563.1 - 9.1e-30 103.8 4.6 5.7e-27 94.7 3.5 3.8 2 1 1 3 3 3 1 MIF4G like CRAL_TRIO PF00650.20 EGC35564.1 - 1.5e-27 96.3 0.2 2.6e-27 95.5 0.2 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGC35564.1 - 4.6e-08 33.1 0.2 1.9e-07 31.2 0.0 2.2 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain DUF3439 PF11921.8 EGC35564.1 - 0.031 14.3 4.4 0.063 13.2 4.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC35564.1 - 0.29 11.1 16.4 1.2 9.1 14.8 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Arrestin_C PF02752.22 EGC35565.1 - 9.1e-19 68.2 2.4 3.7e-16 59.8 1.0 2.5 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain C2 PF00168.30 EGC35565.1 - 2.1e-14 53.6 0.0 4.5e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 C2 domain Arrestin_N PF00339.29 EGC35565.1 - 3.4e-06 27.2 0.1 0.0035 17.4 0.0 3.3 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.30 EGC35565.1 - 8.1e-06 26.2 0.0 1.8e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC35565.1 - 0.13 12.2 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain UPF0697 PF15117.6 EGC35566.1 - 0.08 13.0 0.0 0.11 12.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 PRA1 PF03208.19 EGC35568.1 - 3.6e-24 85.0 2.1 5.8e-24 84.3 2.1 1.3 1 0 0 1 1 1 1 PRA1 family protein FAM199X PF15814.5 EGC35568.1 - 0.33 10.0 3.4 0.43 9.6 3.4 1.1 1 0 0 1 1 1 0 Protein family FAM199X TMCO5 PF14992.6 EGC35568.1 - 4.1 6.9 5.5 9.4 5.7 5.4 1.6 1 1 0 1 1 1 0 TMCO5 family p450 PF00067.22 EGC35569.1 - 1.8e-87 294.1 0.3 2.2e-87 293.8 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 SecY PF00344.20 EGC35570.1 - 6.2e-76 255.6 12.1 7.8e-76 255.2 12.1 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.9 EGC35570.1 - 2.4e-17 62.5 1.0 6.9e-17 61.0 0.1 2.4 2 0 0 2 2 2 1 Plug domain of Sec61p Steroid_dh PF02544.16 EGC35570.1 - 0.0078 16.2 0.3 0.022 14.7 0.3 1.8 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase CBS PF00571.28 EGC35571.1 - 5.6e-19 68.3 1.7 1.7e-05 25.2 0.0 4.2 4 0 0 4 4 4 4 CBS domain CIMR PF00878.18 EGC35572.1 - 5.8e-08 32.9 1.1 1.2e-06 28.7 0.6 2.4 2 0 0 2 2 2 1 Cation-independent mannose-6-phosphate receptor repeat CDC45 PF02724.14 EGC35572.1 - 0.38 9.0 23.1 0.49 8.6 23.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Serinc PF03348.15 EGC35572.1 - 2.4 7.0 5.1 4.1 6.2 5.1 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) Methyltransf_12 PF08242.12 EGC35573.1 - 1 10.2 3.7 1.1 10.0 1.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain FTZ PF03867.14 EGC35573.1 - 5.8 6.4 24.8 7.6 6.0 24.8 1.2 1 0 0 1 1 1 0 Fushi tarazu (FTZ), N-terminal region CBM49 PF09478.10 EGC35575.1 - 1.5e-19 70.1 4.2 1.5e-19 70.1 4.2 2.3 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 GST_N_4 PF17172.4 EGC35576.1 - 0.037 14.8 0.1 0.053 14.3 0.1 1.2 1 0 0 1 1 1 0 Glutathione S-transferase N-terminal domain GNAT_acetyltr_2 PF13718.6 EGC35578.1 - 0.0089 15.5 0.9 0.015 14.7 0.9 1.3 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Pox_Ag35 PF03286.14 EGC35578.1 - 0.58 9.9 7.0 1.1 9.0 7.0 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4834 PF16118.5 EGC35578.1 - 0.93 10.5 7.6 1.9 9.5 7.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) NOA36 PF06524.12 EGC35578.1 - 1.8 7.8 7.6 2.4 7.4 7.6 1.1 1 0 0 1 1 1 0 NOA36 protein DUF2457 PF10446.9 EGC35578.1 - 5.6 6.0 9.0 7.4 5.6 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_S28e PF01200.18 EGC35579.1 - 4.3e-31 106.7 2.3 4.8e-31 106.5 2.3 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Nfu_N PF08712.11 EGC35580.1 - 4.5e-31 106.7 0.0 9e-31 105.8 0.0 1.5 1 0 0 1 1 1 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.17 EGC35580.1 - 8.8e-25 86.7 0.1 1.3e-24 86.1 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain 2OG-FeII_Oxy_2 PF13532.6 EGC35581.1 - 1.3e-41 142.9 0.0 3.4e-41 141.6 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4129 PF13559.6 EGC35581.1 - 0.13 12.5 0.1 0.2 11.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4129) Miga PF10265.9 EGC35583.1 - 0.0081 15.2 5.0 0.01 14.8 5.0 1.1 1 0 0 1 1 1 1 Mitoguardin Macoilin PF09726.9 EGC35583.1 - 0.28 9.7 13.5 0.37 9.3 13.5 1.1 1 0 0 1 1 1 0 Macoilin family CHDCT2 PF08074.11 EGC35583.1 - 0.83 9.8 5.6 7.1 6.8 0.0 2.5 2 1 0 2 2 2 0 CHDCT2 (NUC038) domain Nup84_Nup100 PF04121.13 EGC35584.1 - 6.6e-181 603.1 22.4 6.6e-181 603.1 22.4 1.6 2 0 0 2 2 2 1 Nuclear pore protein 84 / 107 DUF2624 PF11116.8 EGC35584.1 - 7.1 7.6 14.5 3.3 8.7 0.7 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2624) CBM49 PF09478.10 EGC35585.1 - 5.6e-20 71.4 3.9 3e-19 69.1 3.9 2.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGC35586.1 - 1.6e-14 54.0 5.8 4.6e-14 52.5 4.8 2.4 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 Imm43 PF15570.6 EGC35586.1 - 0.05 13.6 1.3 3.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Immunity protein 43 Big_5 PF13205.6 EGC35586.1 - 9.8 6.9 9.5 2.2 9.0 1.0 3.8 3 1 0 3 3 3 0 Bacterial Ig-like domain CBM49 PF09478.10 EGC35587.1 - 1.9e-19 69.8 5.4 1.9e-19 69.8 5.4 3.5 5 0 0 5 5 5 1 Carbohydrate binding domain CBM49 DUF3278 PF11683.8 EGC35588.1 - 0.051 13.7 1.1 0.4 10.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Ribosomal_L27 PF01016.19 EGC35589.1 - 2.6e-36 123.5 0.9 3.2e-36 123.2 0.9 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.6 EGC35589.1 - 0.0016 18.2 0.1 0.0031 17.3 0.1 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region DUF3970 PF13113.6 EGC35589.1 - 0.097 12.9 0.2 1.3 9.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3970) Usp PF00582.26 EGC35590.1 - 1.6e-05 25.4 0.0 9.9e-05 22.9 0.0 2.0 1 1 0 1 1 1 1 Universal stress protein family Glucosamine_iso PF01182.20 EGC35591.1 - 7.7e-23 81.5 0.0 1e-22 81.2 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Drf_GBD PF06371.13 EGC35592.1 - 0.01 15.4 1.6 0.01 15.4 1.6 1.0 1 0 0 1 1 1 0 Diaphanous GTPase-binding Domain Pilin_PilX PF11530.8 EGC35592.1 - 0.046 13.6 0.7 0.048 13.6 0.7 1.0 1 0 0 1 1 1 0 Minor type IV pilin, PilX Mito_carr PF00153.27 EGC35593.1 - 3.8e-77 254.3 1.8 2.4e-25 88.3 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGC35593.1 - 1.1e-10 41.8 1.8 2.2e-10 40.8 1.8 1.6 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.32 EGC35593.1 - 1.3e-10 40.0 2.9 1.8e-05 23.9 0.4 2.8 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGC35593.1 - 2e-08 33.5 0.6 4.1e-05 23.2 0.3 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGC35593.1 - 1.1e-07 31.0 2.0 1.6e-05 24.2 1.0 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC35593.1 - 0.0023 17.8 2.5 0.34 10.8 0.3 2.5 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC35593.1 - 0.0034 17.7 3.8 0.0056 17.0 3.8 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region YecM PF06185.12 EGC35594.1 - 2.2e-37 128.5 0.4 2.5e-37 128.3 0.4 1.0 1 0 0 1 1 1 1 YecM protein RE_HpaII PF09561.10 EGC35594.1 - 0.0071 15.8 0.2 0.011 15.2 0.2 1.3 1 0 0 1 1 1 1 HpaII restriction endonuclease tRNA-synt_1g PF09334.11 EGC35595.1 - 8.5e-110 367.2 0.2 3.5e-109 365.1 0.2 1.9 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.22 EGC35595.1 - 3.9e-24 84.9 4.9 6.6e-13 47.8 1.1 3.8 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.19 EGC35595.1 - 9.3e-09 35.0 0.0 0.0026 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.13 EGC35595.1 - 0.00065 19.7 0.0 0.003 17.5 0.0 2.1 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1f PF01921.18 EGC35595.1 - 0.016 14.2 0.0 0.2 10.5 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) tRNA-synt_1c PF00749.21 EGC35595.1 - 0.14 11.0 0.4 0.38 9.6 0.3 1.6 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain zinc_ribbon_10 PF10058.9 EGC35596.1 - 6.2e-11 41.9 1.1 1.2e-10 41.0 1.1 1.5 1 0 0 1 1 1 1 Predicted integral membrane zinc-ribbon metal-binding protein Hid1 PF12722.7 EGC35596.1 - 0.00067 17.9 10.9 0.00079 17.7 10.9 1.1 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein DUF2207 PF09972.9 EGC35596.1 - 0.0021 16.9 4.1 0.0021 16.9 4.1 2.1 2 0 0 2 2 1 1 Predicted membrane protein (DUF2207) Lin-8 PF03353.15 EGC35596.1 - 0.0023 17.6 18.9 0.0038 16.8 18.9 1.3 1 0 0 1 1 1 1 Ras-mediated vulval-induction antagonist Suf PF05843.14 EGC35596.1 - 0.0049 16.9 22.1 0.0073 16.3 22.1 1.3 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) DUF1178 PF06676.11 EGC35596.1 - 0.014 15.8 8.0 0.029 14.8 8.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1178) XRN_M PF17846.1 EGC35596.1 - 0.029 13.3 9.5 0.042 12.8 9.5 1.1 1 0 0 1 1 1 0 Xrn1 helical domain SRP-alpha_N PF04086.13 EGC35596.1 - 0.034 14.1 13.2 0.054 13.4 13.2 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Endostatin PF06482.11 EGC35596.1 - 0.045 13.2 13.4 0.061 12.8 13.4 1.1 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin TFIIA PF03153.13 EGC35596.1 - 0.06 13.3 40.6 0.084 12.9 40.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DDHD PF02862.17 EGC35596.1 - 0.067 13.3 9.8 0.11 12.6 9.8 1.4 1 0 0 1 1 1 0 DDHD domain Hamartin PF04388.12 EGC35596.1 - 0.096 11.3 14.2 0.13 10.9 14.2 1.1 1 0 0 1 1 1 0 Hamartin protein GAGA_bind PF06217.12 EGC35596.1 - 0.12 12.6 13.3 0.16 12.3 13.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Eapp_C PF10238.9 EGC35596.1 - 0.17 11.9 12.8 0.022 14.8 7.8 1.9 2 0 0 2 2 2 0 E2F-associated phosphoprotein DUF935 PF06074.12 EGC35596.1 - 0.28 9.9 9.8 0.33 9.6 9.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF935) PAT1 PF09770.9 EGC35596.1 - 0.4 8.9 27.1 0.49 8.6 27.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF702 PF05142.12 EGC35596.1 - 0.81 10.2 12.8 0.49 10.9 10.0 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF702) RR_TM4-6 PF06459.12 EGC35596.1 - 0.87 9.4 18.0 1.4 8.6 18.0 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Hydin_ADK PF17213.3 EGC35596.1 - 2.8 8.2 12.2 4.4 7.5 12.2 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain PepSY_TM PF03929.16 EGC35596.1 - 3.1 7.4 8.4 4.4 6.9 8.4 1.3 1 0 0 1 1 1 0 PepSY-associated TM region SLC12 PF03522.15 EGC35596.1 - 3.4 6.6 19.5 4.8 6.1 19.5 1.2 1 0 0 1 1 1 0 Solute carrier family 12 CIAPIN1 PF05093.13 EGC35596.1 - 5.5 7.6 12.9 0.95 10.0 8.8 1.9 2 1 0 2 2 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis OATP PF03137.20 EGC35596.1 - 6.5 4.9 8.8 4.5 5.4 7.2 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family DUF4407 PF14362.6 EGC35596.1 - 6.8 6.0 16.0 11 5.2 16.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pkinase_fungal PF17667.1 EGC35596.1 - 6.9 5.3 9.7 9.7 4.8 9.7 1.1 1 0 0 1 1 1 0 Fungal protein kinase PEX11 PF05648.14 EGC35596.1 - 8.1 5.8 7.9 3.5 7.0 5.2 1.7 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) PH_11 PF15413.6 EGC35596.1 - 8.9 6.8 10.2 21 5.6 0.3 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain GREB1 PF15782.5 EGC35596.1 - 9 3.3 18.7 11 2.9 18.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Zip PF02535.22 EGC35596.1 - 9.2 5.4 9.3 13 4.9 8.9 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter TrmO PF01980.16 EGC35597.1 - 2e-41 140.9 0.3 5e-28 97.7 0.2 2.5 1 1 1 2 2 2 2 tRNA-methyltransferase O SUIM_assoc PF16619.5 EGC35597.1 - 0.18 11.9 16.3 0.36 10.9 8.3 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mucin PF01456.17 EGC35597.1 - 0.39 10.7 19.1 0.062 13.3 15.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGC35597.1 - 0.46 10.4 9.3 0.026 14.5 3.8 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Ctr PF04145.15 EGC35597.1 - 0.71 10.5 2.3 0.73 10.4 0.9 1.7 2 0 0 2 2 2 0 Ctr copper transporter family SSP160 PF06933.11 EGC35597.1 - 0.93 7.6 11.6 1.4 7.1 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CPSF100_C PF13299.6 EGC35597.1 - 0.99 9.6 6.4 0.25 11.5 2.8 1.8 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Presenilin PF01080.17 EGC35597.1 - 6.4 5.4 7.6 11 4.7 7.6 1.3 1 0 0 1 1 1 0 Presenilin DUF327 PF03885.13 EGC35598.1 - 6.5 6.7 9.5 60 3.6 9.5 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF327) DJ-1_PfpI PF01965.24 EGC35599.1 - 6.1e-32 110.7 0.0 7.3e-32 110.4 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family GATase_3 PF07685.14 EGC35599.1 - 0.0045 16.6 0.0 0.0059 16.2 0.0 1.2 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_5 PF13507.6 EGC35599.1 - 0.013 14.6 0.0 0.029 13.5 0.0 1.6 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ThiJ_like PF17124.5 EGC35599.1 - 0.037 13.7 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 ThiJ/PfpI family-like GATase PF00117.28 EGC35599.1 - 0.045 13.5 0.0 0.063 13.0 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Actin PF00022.19 EGC35600.1 - 2.7e-98 329.3 0.1 4e-98 328.7 0.1 1.3 1 1 0 1 1 1 1 Actin MRP-S33 PF08293.11 EGC35600.1 - 0.00064 19.9 0.3 0.0016 18.6 0.3 1.6 1 0 0 1 1 1 1 Mitochondrial ribosomal subunit S27 MreB_Mbl PF06723.13 EGC35600.1 - 0.0014 17.5 0.0 0.38 9.5 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein DHFR_1 PF00186.19 EGC35600.1 - 0.061 13.0 0.0 0.24 11.1 0.0 2.0 3 0 0 3 3 3 0 Dihydrofolate reductase TLD PF07534.16 EGC35601.1 - 6.8e-36 123.6 2.1 6.8e-36 123.6 2.1 3.4 5 1 0 5 5 5 1 TLD hSac2 PF12456.8 EGC35601.1 - 4.3e-17 61.9 0.4 1.2e-16 60.4 0.1 1.9 2 0 0 2 2 2 1 Inositol phosphatase DUF4175 PF13779.6 EGC35601.1 - 0.41 8.5 7.3 0.62 7.9 7.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) CBFD_NFYB_HMF PF00808.23 EGC35602.1 - 1.8e-18 66.5 0.7 2.8e-18 66.0 0.7 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC35602.1 - 0.003 17.9 0.1 0.0041 17.5 0.1 1.4 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Pox_RNA_Pol_19 PF05320.12 EGC35602.1 - 0.038 14.0 0.2 0.044 13.8 0.2 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit TFIID_20kDa PF03847.13 EGC35602.1 - 0.046 14.2 0.2 0.091 13.3 0.1 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A TFIID-18kDa PF02269.16 EGC35602.1 - 0.1 12.6 0.2 0.3 11.1 0.1 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit TAFII28 PF04719.14 EGC35602.1 - 0.11 12.7 0.4 0.2 11.7 0.2 1.5 2 0 0 2 2 2 0 hTAFII28-like protein conserved region p450 PF00067.22 EGC35606.1 - 1.5e-85 287.7 3.6 1.8e-85 287.5 3.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 FNIP PF05725.12 EGC35608.1 - 9.9e-106 345.7 34.6 1.3e-17 63.7 0.2 8.0 5 2 4 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.13 EGC35608.1 - 0.018 15.4 0.0 47 4.4 0.0 5.0 3 2 2 5 5 5 0 Phage minor tail protein SSURE PF11966.8 EGC35608.1 - 0.036 13.8 6.3 13 5.6 0.0 5.7 2 2 3 7 7 7 0 Fibronectin-binding repeat LRR_1 PF00560.33 EGC35608.1 - 0.41 11.4 11.4 89 4.3 0.1 7.1 3 2 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.12 EGC35609.1 - 4.1e-168 545.4 64.3 1.7e-16 60.1 0.2 13.1 9 2 5 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.13 EGC35609.1 - 8.8e-06 26.1 0.0 97 3.4 0.0 8.0 6 3 4 11 11 11 0 Phage minor tail protein B-block_TFIIIC PF04182.12 EGC35611.1 - 3.8e-16 59.0 4.3 5.8e-14 52.0 0.2 3.6 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC HTH_24 PF13412.6 EGC35611.1 - 0.23 11.0 1.4 17 5.0 0.1 3.6 3 0 0 3 3 3 0 Winged helix-turn-helix DNA-binding FYDLN_acid PF09538.10 EGC35613.1 - 9.7 6.9 24.0 2.9 8.6 12.5 3.2 2 1 0 2 2 2 0 Protein of unknown function (FYDLN_acid) Mito_carr PF00153.27 EGC35614.1 - 1.2e-70 233.5 2.3 1.4e-22 79.4 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGC35614.1 - 0.12 12.6 0.0 27 5.1 0.0 3.4 3 1 0 4 4 4 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase LRR_6 PF13516.6 EGC35615.1 - 8.9e-09 34.7 34.3 0.0033 17.4 2.0 7.1 7 0 0 7 7 7 5 Leucine Rich repeat LRR_4 PF12799.7 EGC35615.1 - 0.00029 21.1 4.6 0.00029 21.1 4.6 7.2 3 2 3 7 7 7 2 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGC35615.1 - 0.045 13.6 0.4 0.11 12.4 0.4 1.6 1 0 0 1 1 1 0 F-box-like DAO PF01266.24 EGC35616.1 - 1.1e-42 146.9 0.0 1.2e-42 146.7 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.22 EGC35616.1 - 3.9e-07 29.5 0.0 0.00029 20.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A HI0933_like PF03486.14 EGC35616.1 - 1.8e-05 23.6 0.1 0.072 11.8 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.24 EGC35616.1 - 2.2e-05 23.7 0.0 0.007 15.5 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain Pyr_redox_2 PF07992.14 EGC35616.1 - 6.9e-05 22.2 0.1 0.051 12.8 0.0 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC35616.1 - 0.00019 21.6 0.1 0.00046 20.4 0.1 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGC35616.1 - 0.00071 18.9 0.4 0.32 10.2 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC35616.1 - 0.00099 18.4 0.0 0.0018 17.5 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.7 EGC35616.1 - 0.013 14.9 0.0 0.021 14.2 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Amino_oxidase PF01593.24 EGC35616.1 - 0.036 13.4 0.0 0.038 13.3 0.0 1.3 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase 3HCDH_N PF02737.18 EGC35616.1 - 0.099 12.5 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain FAD_binding_3 PF01494.19 EGC35616.1 - 0.25 10.5 0.0 0.48 9.6 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PEX11 PF05648.14 EGC35617.1 - 0.00082 18.9 0.1 0.00082 18.9 0.1 3.5 3 0 0 3 3 3 1 Peroxisomal biogenesis factor 11 (PEX11) PEPCK_ATP PF01293.20 EGC35618.1 - 4.7e-19 68.4 1.6 1.7e-10 40.2 0.0 2.7 2 1 0 2 2 2 2 Phosphoenolpyruvate carboxykinase TMEM154 PF15102.6 EGC35619.1 - 3.8e-05 23.6 0.8 6.6e-05 22.8 0.8 1.3 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.10 EGC35620.1 - 0.00043 20.3 12.6 0.0014 18.6 9.0 2.7 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF4448 PF14610.6 EGC35620.1 - 0.0019 18.0 1.5 0.0021 17.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) TMEM154 PF15102.6 EGC35620.1 - 0.0096 15.8 8.6 0.0096 15.8 8.6 1.8 1 1 1 2 2 2 1 TMEM154 protein family Insulin_TMD PF17870.1 EGC35620.1 - 0.022 14.8 3.7 0.064 13.3 3.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment DUF1180 PF06679.12 EGC35620.1 - 0.03 14.7 0.3 0.046 14.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Orf78 PF06024.12 EGC35620.1 - 0.19 12.0 5.9 0.19 12.1 3.9 2.0 1 1 1 2 2 2 0 Orf78 (ac78) DUF2905 PF11146.8 EGC35620.1 - 0.38 10.9 4.7 0.87 9.8 0.7 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) IMUP PF15761.5 EGC35620.1 - 8.8 7.1 12.8 24 5.7 12.8 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein Macoilin PF09726.9 EGC35620.1 - 10 4.6 13.2 14 4.0 13.2 1.2 1 0 0 1 1 1 0 Macoilin family ATP_bind_1 PF03029.17 EGC35622.1 - 2.3e-89 299.3 0.2 2.6e-89 299.2 0.2 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CLP1_P PF16575.5 EGC35622.1 - 5.1e-05 23.1 0.0 0.0038 17.0 0.0 2.4 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop GTP_EFTU PF00009.27 EGC35622.1 - 0.00019 21.0 0.0 0.0013 18.3 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_30 PF13604.6 EGC35622.1 - 0.0021 17.8 0.0 0.003 17.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC35622.1 - 0.011 16.3 0.2 0.077 13.5 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC35622.1 - 0.012 15.3 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC35622.1 - 0.019 14.9 0.3 9.4 6.1 0.0 3.1 2 1 2 4 4 4 0 RsgA GTPase AAA_24 PF13479.6 EGC35622.1 - 0.021 14.6 0.0 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 AAA domain KTI12 PF08433.10 EGC35622.1 - 0.024 14.1 0.0 0.13 11.7 0.0 1.9 2 0 0 2 2 2 0 Chromatin associated protein KTI12 AAA_16 PF13191.6 EGC35622.1 - 0.03 14.7 0.0 0.095 13.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.6 EGC35622.1 - 0.063 13.6 0.0 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.22 EGC35622.1 - 0.14 12.6 0.0 0.24 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGC35622.1 - 0.16 11.5 0.0 0.34 10.4 0.0 1.6 2 0 0 2 2 2 0 P-loop containing dynein motor region PduV-EutP PF10662.9 EGC35622.1 - 0.18 11.6 0.1 16 5.2 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.22 EGC35622.1 - 0.18 11.4 0.0 0.42 10.2 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Methyltransf_16 PF10294.9 EGC35623.1 - 1e-22 80.7 0.6 1.4e-22 80.3 0.6 1.2 1 0 0 1 1 1 1 Lysine methyltransferase MTS PF05175.14 EGC35623.1 - 8.4e-06 25.4 0.1 1.3e-05 24.8 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGC35623.1 - 0.0038 17.9 0.0 0.0091 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC35623.1 - 0.0058 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC35623.1 - 0.019 14.7 0.5 0.042 13.6 0.5 1.6 1 1 0 1 1 1 0 Methyltransferase domain TehB PF03848.14 EGC35623.1 - 0.024 14.1 0.2 0.037 13.4 0.2 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB PrmA PF06325.13 EGC35623.1 - 0.053 12.9 0.0 0.081 12.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) SAM_MT PF04445.13 EGC35623.1 - 0.056 12.9 0.0 0.075 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative SAM-dependent methyltransferase Pheromone PF08015.11 EGC35625.1 - 0.051 14.6 0.2 0.057 14.5 0.2 1.1 1 0 0 1 1 1 0 Fungal mating-type pheromone CBS PF00571.28 EGC35626.1 - 9.6e-24 83.6 3.9 2.6e-13 50.2 0.3 2.3 2 0 0 2 2 2 2 CBS domain Rubredoxin_C PF18267.1 EGC35626.1 - 0.034 14.1 1.6 0.61 10.0 0.7 2.4 2 0 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain Prenyltrans PF00432.21 EGC35627.1 - 6e-67 221.1 1.9 5.1e-13 48.5 0.3 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SQHop_cyclase_C PF13243.6 EGC35627.1 - 2.1e-07 30.4 0.1 1.9e-05 23.9 0.0 2.5 1 1 1 2 2 2 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGC35627.1 - 6.3e-06 25.5 0.0 0.061 12.4 0.0 3.8 2 2 2 4 4 4 2 Squalene-hopene cyclase N-terminal domain TED_complement PF07678.14 EGC35627.1 - 0.0011 18.1 0.1 1.5 7.8 0.0 3.5 2 1 2 4 4 4 2 A-macroglobulin TED domain PI3K_1B_p101 PF10486.9 EGC35628.1 - 0.2 9.4 7.4 0.25 9.1 7.4 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpb5_N PF03871.14 EGC35628.1 - 1.5 9.5 5.0 0.22 12.1 0.4 1.9 2 1 0 2 2 2 0 RNA polymerase Rpb5, N-terminal domain RMI2 PF16100.5 EGC35629.1 - 1.6e-07 31.2 0.0 2.9e-07 30.4 0.0 1.5 1 0 0 1 1 1 1 RecQ-mediated genome instability protein 2 FLgD_tudor PF13861.6 EGC35629.1 - 0.061 13.6 0.0 15 5.9 0.0 2.3 2 0 0 2 2 2 0 FlgD Tudor-like domain Cellulase PF00150.18 EGC35631.1 - 5.3e-39 134.3 0.5 8.7e-39 133.6 0.5 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) DUF4685 PF15737.5 EGC35632.1 - 0.19 12.2 7.2 0.89 10.0 0.2 2.6 1 1 2 3 3 3 0 Domain of unknown function (DUF4685) MYEOV2 PF15004.6 EGC35633.1 - 0.17 12.3 19.2 1.5 9.3 19.2 2.1 1 1 0 1 1 1 0 Myeloma-overexpressed-like zf-RING_2 PF13639.6 EGC35634.1 - 1.2e-09 38.3 8.0 1.9e-09 37.7 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGC35634.1 - 2e-07 31.2 7.6 4.7e-07 30.0 7.6 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC35634.1 - 5.7e-07 29.4 4.8 9.9e-07 28.7 4.8 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC35634.1 - 1.2e-06 28.2 4.6 1.8e-06 27.7 4.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35634.1 - 1.5e-06 27.9 6.3 2.3e-06 27.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC35634.1 - 2.8e-05 23.9 6.0 4.5e-05 23.2 6.0 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC35634.1 - 7.4e-05 22.6 5.4 0.00019 21.3 5.4 1.7 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC35634.1 - 0.00014 21.6 7.4 0.00024 20.8 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGC35634.1 - 0.0041 16.7 4.3 0.0096 15.5 4.3 1.6 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-ANAPC11 PF12861.7 EGC35634.1 - 0.0062 16.6 5.4 0.03 14.4 5.4 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC35634.1 - 0.041 14.0 5.0 0.073 13.2 5.0 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING-like PF08746.11 EGC35634.1 - 0.55 10.6 5.4 0.87 10.0 5.4 1.3 1 0 0 1 1 1 0 RING-like domain zf-RING_4 PF14570.6 EGC35634.1 - 0.95 9.3 5.2 11 5.9 5.4 2.1 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RINGv PF12906.7 EGC35634.1 - 1.3 9.2 5.7 2.7 8.2 5.7 1.5 1 1 0 1 1 1 0 RING-variant domain DUF2968 PF11180.8 EGC35635.1 - 0.22 11.1 5.6 0.49 10.0 5.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4407 PF14362.6 EGC35635.1 - 0.88 8.9 9.7 1.2 8.5 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAS_10 PF13596.6 EGC35635.1 - 2.3 8.8 6.3 1.1 9.8 0.1 2.8 1 1 2 3 3 3 0 PAS domain IQCJ-SCHIP1 PF15157.6 EGC35635.1 - 7.1 6.5 9.9 8.6 6.2 0.1 2.3 2 0 0 2 2 2 0 Fusion protein IQCJ-SCHIP1 with IQ-like motif OTU PF02338.19 EGC35636.1 - 6.6e-14 52.5 0.8 1e-13 51.9 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4834 PF16118.5 EGC35636.1 - 0.0021 19.0 7.5 0.007 17.3 7.5 1.9 1 1 0 1 1 1 1 Domain of unknown function (DUF4834) BRF1 PF07741.13 EGC35636.1 - 0.0035 17.7 3.7 0.0068 16.7 3.7 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Ctr PF04145.15 EGC35636.1 - 0.0052 17.4 0.5 0.0094 16.6 0.5 1.4 1 0 0 1 1 1 1 Ctr copper transporter family TssO PF17561.2 EGC35636.1 - 0.015 15.4 0.7 0.015 15.4 0.7 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO SARAF PF06682.12 EGC35636.1 - 0.018 14.7 5.0 0.026 14.2 5.0 1.2 1 0 0 1 1 1 0 SOCE-associated regulatory factor of calcium homoeostasis UPF0767 PF15990.5 EGC35636.1 - 0.02 15.1 1.5 0.08 13.1 0.1 2.2 1 1 1 2 2 2 0 UPF0767 family TFIIA PF03153.13 EGC35636.1 - 0.025 14.6 21.4 0.03 14.3 21.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.22 EGC35636.1 - 0.078 12.2 1.2 0.1 11.8 1.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter EMC3_TMCO1 PF01956.16 EGC35636.1 - 0.11 12.2 1.0 0.2 11.4 1.0 1.5 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like ABC2_membrane_3 PF12698.7 EGC35636.1 - 0.14 11.3 0.3 0.22 10.6 0.1 1.5 2 0 0 2 2 2 0 ABC-2 family transporter protein CLN3 PF02487.17 EGC35636.1 - 0.24 10.4 1.7 0.31 10.0 1.7 1.2 1 0 0 1 1 1 0 CLN3 protein PAT1 PF09770.9 EGC35636.1 - 0.56 8.4 17.9 0.65 8.2 17.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM60A PF15396.6 EGC35636.1 - 0.66 9.9 7.1 1 9.4 7.1 1.2 1 0 0 1 1 1 0 Protein Family FAM60A Tim54 PF11711.8 EGC35636.1 - 4.5 5.9 11.0 6 5.5 11.0 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Neur_chan_memb PF02932.16 EGC35636.1 - 5.1 7.1 8.1 7.2 6.6 8.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Presenilin PF01080.17 EGC35636.1 - 7.6 5.2 12.5 9.9 4.8 12.5 1.1 1 0 0 1 1 1 0 Presenilin AKAP7_NLS PF10469.9 EGC35638.1 - 3.9e-17 62.8 6.7 4.4e-17 62.7 6.7 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.6 EGC35638.1 - 0.00078 19.4 0.0 0.0015 18.4 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily TFIIS_M PF07500.14 EGC35638.1 - 0.95 10.0 4.0 1.2 9.6 1.7 2.3 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain FYVE PF01363.21 EGC35640.1 - 4.4e-18 65.2 10.1 8e-18 64.3 10.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_C PF02752.22 EGC35640.1 - 5.3e-15 56.0 0.0 3.9e-13 50.0 0.0 2.6 2 1 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.29 EGC35640.1 - 5.3e-15 55.7 0.4 3.5e-12 46.6 0.1 3.1 2 1 0 2 2 2 2 Arrestin (or S-antigen), N-terminal domain FYVE_2 PF02318.16 EGC35640.1 - 0.044 14.0 6.7 0.11 12.8 6.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger Big_3_4 PF13754.6 EGC35640.1 - 0.092 12.5 0.0 0.22 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function DSPc PF00782.20 EGC35641.1 - 1.2e-07 31.6 0.0 5.1e-07 29.6 0.0 1.9 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC35641.1 - 9.8e-06 25.3 0.0 1.3e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGC35641.1 - 0.0016 18.4 0.0 0.0035 17.3 0.0 1.5 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGC35641.1 - 0.0017 17.9 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGC35641.1 - 0.039 14.1 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Glyco_hydro_47 PF01532.20 EGC35642.1 - 9.7e-143 476.4 0.1 1.1e-142 476.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.11 EGC35642.1 - 8.5e-05 22.0 0.0 1.6 7.9 0.0 3.8 3 1 1 4 4 4 2 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) Glyco_hydro_76 PF03663.14 EGC35642.1 - 9.6e-05 22.0 0.5 2.1 7.8 0.0 3.7 2 1 1 3 3 3 2 Glycosyl hydrolase family 76 DUF1484 PF07363.11 EGC35643.1 - 0.094 13.7 0.0 0.15 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) Sod_Cu PF00080.20 EGC35644.1 - 2.3e-34 118.6 1.0 1.7e-26 93.1 2.8 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Myb_DNA-binding PF00249.31 EGC35645.1 - 0.0057 16.8 2.0 0.013 15.6 0.0 2.7 3 0 0 3 3 3 1 Myb-like DNA-binding domain Sorb PF02208.16 EGC35645.1 - 0.41 10.5 4.6 1.4 8.9 0.3 3.1 3 0 0 3 3 3 0 Sorbin homologous domain I_LWEQ PF01608.17 EGC35646.1 - 0.00085 19.6 0.0 0.00089 19.5 0.0 1.1 1 0 0 1 1 1 1 I/LWEQ domain Methyltransf_12 PF08242.12 EGC35647.1 - 0.11 13.3 0.3 0.16 12.7 0.3 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2418 PF10332.9 EGC35647.1 - 4.4 7.9 11.6 65 4.2 11.6 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2418) RUN PF02759.19 EGC35648.1 - 8.8e-07 28.9 0.2 8.8e-07 28.9 0.2 2.0 2 0 0 2 2 2 1 RUN domain SUIM_assoc PF16619.5 EGC35648.1 - 0.0039 17.2 3.2 0.008 16.2 3.2 1.5 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2126 PF09899.9 EGC35648.1 - 3.5 5.6 5.7 4.8 5.1 5.7 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) FAD_binding_3 PF01494.19 EGC35649.1 - 4.2e-20 72.3 0.0 1.1e-19 71.0 0.0 1.7 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGC35649.1 - 0.00026 20.1 0.0 0.0037 16.4 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase NAD_binding_8 PF13450.6 EGC35649.1 - 0.0017 18.5 0.0 0.0039 17.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.24 EGC35649.1 - 0.0024 17.5 0.0 0.023 14.3 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGC35649.1 - 0.0072 15.6 0.0 0.018 14.3 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Defensin_int PF17858.1 EGC35652.1 - 9.7 6.3 12.4 5 7.2 0.6 3.9 3 0 0 3 3 3 0 Platypus intermediate defensin-like peptide DUF2752 PF10825.8 EGC35653.1 - 0.0025 17.8 0.1 0.0072 16.4 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2752) DHR-2 PF06920.13 EGC35654.1 - 2e-169 564.6 14.6 2e-169 564.6 14.6 2.7 2 1 1 3 3 3 1 Dock homology region 2 DOCK-C2 PF14429.6 EGC35654.1 - 2.9e-41 141.4 0.9 1.2e-40 139.5 0.4 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3398 PF11878.8 EGC35654.1 - 0.00079 19.8 4.7 0.0015 18.9 3.0 2.4 1 1 0 1 1 1 1 Domain of unknown function (DUF3398) Usp PF00582.26 EGC35655.1 - 2.1e-23 83.4 0.0 2.7e-23 83.1 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Peripla_BP_5 PF13433.6 EGC35655.1 - 0.0049 15.9 0.1 0.063 12.3 0.1 2.0 2 0 0 2 2 2 1 Periplasmic binding protein domain VWA_2 PF13519.6 EGC35655.1 - 0.035 14.8 0.0 0.074 13.7 0.0 1.6 2 0 0 2 2 2 0 von Willebrand factor type A domain Oxidored_nitro PF00148.19 EGC35655.1 - 0.038 12.7 0.0 0.049 12.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase DUF896 PF05979.12 EGC35655.1 - 0.061 13.2 0.1 0.54 10.2 0.1 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF896) B12-binding PF02310.19 EGC35655.1 - 0.1 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain SBP_bac_3 PF00497.20 EGC35655.1 - 0.12 11.8 0.0 12 5.3 0.0 2.2 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 Glyco_tran_WecB PF03808.13 EGC35655.1 - 0.18 11.8 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase WecB/TagA/CpsF family Phosducin PF02114.16 EGC35656.1 - 2.4e-24 85.7 3.8 3.3e-21 75.4 0.2 2.3 1 1 1 2 2 2 2 Phosducin Dicty_CTDC PF00526.18 EGC35657.1 - 6.2e-12 45.2 60.4 4.9e-06 26.3 4.2 11.8 14 0 0 14 14 14 7 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC35657.1 - 5e-06 26.4 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF737 PF05300.11 EGC35658.1 - 0.0057 17.0 10.7 0.0057 17.0 10.7 2.7 1 1 1 2 2 2 1 Protein of unknown function (DUF737) CLZ PF16526.5 EGC35658.1 - 0.022 15.1 10.1 0.022 15.1 10.1 5.1 2 2 3 5 5 5 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels AAA_15 PF13175.6 EGC35658.1 - 0.51 10.0 60.3 0.87 9.2 60.3 1.3 1 0 0 1 1 1 0 AAA ATPase domain DUF3584 PF12128.8 EGC35658.1 - 4.5 4.7 59.9 2.8 5.4 31.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) TMF_TATA_bd PF12325.8 EGC35658.1 - 4.9 7.4 67.9 0.052 13.8 11.8 5.1 1 1 3 4 4 4 0 TATA element modulatory factor 1 TATA binding Golgin_A5 PF09787.9 EGC35658.1 - 6.5 6.1 72.0 0.036 13.5 29.0 2.6 1 1 1 2 2 2 0 Golgin subfamily A member 5 MOR2-PAG1_N PF14222.6 EGC35659.1 - 9.1e-111 371.5 5.2 9.1e-111 371.5 5.2 2.4 2 0 0 2 2 2 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.6 EGC35659.1 - 2.4e-68 230.8 8.8 9e-27 93.2 0.9 4.2 2 1 2 4 4 4 4 Cell morphogenesis central region MOR2-PAG1_C PF14225.6 EGC35659.1 - 1.9e-48 165.5 1.5 5.6e-48 164.0 0.1 2.7 2 0 0 2 2 2 1 Cell morphogenesis C-terminal Chorismate_synt PF01264.21 EGC35659.1 - 3.3 6.4 5.5 7 5.3 5.5 1.5 1 0 0 1 1 1 0 Chorismate synthase NDK PF00334.19 EGC35660.1 - 3.6e-32 111.2 0.0 4.4e-32 110.9 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Ependymin PF00811.18 EGC35661.1 - 0.13 12.5 1.7 0.43 10.8 1.7 1.8 1 1 0 1 1 1 0 Ependymin BTB PF00651.31 EGC35662.1 - 1e-18 67.6 0.0 3.7e-18 65.8 0.0 1.9 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.15 EGC35662.1 - 5.7e-05 23.2 0.1 0.00052 20.1 0.0 2.3 2 0 0 2 2 2 1 BTB And C-terminal Kelch RRN3 PF05327.11 EGC35662.1 - 0.19 10.2 9.7 0.3 9.6 9.7 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RNA_pol_3_Rpc31 PF11705.8 EGC35662.1 - 0.22 11.7 16.9 0.4 10.9 16.9 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 SGT1 PF07093.11 EGC35662.1 - 1.7 7.0 11.2 2.7 6.3 11.2 1.2 1 0 0 1 1 1 0 SGT1 protein CDC45 PF02724.14 EGC35662.1 - 8.1 4.6 10.9 13 3.9 10.9 1.4 1 0 0 1 1 1 0 CDC45-like protein Terpene_synth_C PF03936.16 EGC35663.1 - 0.0059 16.0 0.6 0.036 13.4 0.6 2.0 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.16 EGC35664.1 - 2.4e-38 132.0 9.0 2.4e-38 132.0 9.0 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_1_like PF12832.7 EGC35664.1 - 2.9e-06 26.4 7.8 2.9e-05 23.1 3.5 2.4 1 1 1 2 2 2 2 MFS_1 like family MFS_2 PF13347.6 EGC35664.1 - 0.00032 19.4 29.0 0.0031 16.1 10.2 2.7 2 2 0 2 2 2 2 MFS/sugar transport protein DUF4131 PF13567.6 EGC35664.1 - 3.6 7.2 0.0 3.6 7.2 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Rhomboid PF01694.22 EGC35665.1 - 1.5e-21 77.0 7.4 2.5e-21 76.2 7.4 1.2 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.10 EGC35665.1 - 0.056 14.0 0.1 0.1 13.2 0.1 1.5 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Syja_N PF02383.18 EGC35666.1 - 7.4e-79 265.4 4.8 7.4e-79 265.4 4.8 1.9 2 0 0 2 2 2 1 SacI homology domain DUF2096 PF09869.9 EGC35666.1 - 0.038 14.1 0.1 0.087 12.9 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) RRM_1 PF00076.22 EGC35667.1 - 5.8e-24 83.7 3.5 5.3e-11 42.2 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC35667.1 - 4e-08 33.3 0.4 0.0027 17.8 0.0 2.8 2 0 0 2 2 2 2 RNA recognition motif Sua5_yciO_yrdC PF01300.18 EGC35669.1 - 2.2e-45 154.3 0.0 4e-45 153.5 0.0 1.4 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.13 EGC35669.1 - 6.7e-13 49.4 0.0 1.1e-12 48.7 0.0 1.3 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding EGF_2 PF07974.13 EGC35670.1 - 0.00012 22.4 13.0 0.00012 22.4 13.0 3.5 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.24 EGC35670.1 - 0.00074 19.6 20.5 0.055 13.6 9.2 2.7 2 0 0 2 2 2 2 Laminin EGF domain TIG PF01833.24 EGC35670.1 - 0.00083 19.4 2.8 0.00083 19.4 2.8 3.3 2 1 0 2 2 2 1 IPT/TIG domain EGF_Tenascin PF18720.1 EGC35670.1 - 0.0023 17.9 10.2 0.0048 16.9 2.0 2.8 2 0 0 2 2 2 2 Tenascin EGF domain DUF4064 PF13273.6 EGC35670.1 - 3.7 7.9 6.3 30 5.0 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) HEPN PF05168.14 EGC35671.1 - 0.016 15.3 1.5 0.051 13.7 0.2 2.4 1 1 1 2 2 2 0 HEPN domain LptF_LptG PF03739.14 EGC35671.1 - 0.4 9.5 4.0 0.57 9.0 4.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG HATPase_c_3 PF13589.6 EGC35672.1 - 0.002 18.0 1.5 0.36 10.7 0.0 3.4 3 1 0 3 3 3 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Protoglobin PF11563.8 EGC35672.1 - 0.032 14.1 0.4 0.19 11.6 0.1 2.4 2 0 0 2 2 2 0 Protoglobin HATPase_c_3 PF13589.6 EGC35673.1 - 0.0089 15.9 4.1 0.19 11.5 0.4 3.2 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Protoglobin PF11563.8 EGC35673.1 - 0.081 12.8 0.3 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 Protoglobin HEPN PF05168.14 EGC35674.1 - 0.00012 22.2 2.3 0.03 14.5 0.3 3.0 2 0 0 2 2 2 2 HEPN domain HATPase_c_3 PF13589.6 EGC35674.1 - 0.00066 19.5 2.8 0.035 13.9 0.2 3.2 2 1 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.6 EGC35675.1 - 0.0089 15.9 5.1 0.18 11.7 0.8 3.3 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN PF05168.14 EGC35675.1 - 0.0092 16.1 0.4 0.23 11.6 0.1 3.0 2 0 0 2 2 2 1 HEPN domain EFP PF01132.20 EGC35675.1 - 0.013 15.5 2.6 1.1 9.3 0.3 4.4 3 0 0 3 3 3 0 Elongation factor P (EF-P) OB domain HEPN PF05168.14 EGC35676.1 - 0.029 14.5 0.3 0.5 10.5 0.0 3.1 2 0 0 2 2 2 0 HEPN domain HATPase_c_3 PF13589.6 EGC35676.1 - 0.13 12.1 4.2 6 6.7 0.4 3.4 2 2 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase T3SS_basalb_I PF17001.5 EGC35676.1 - 0.17 12.5 1.4 4.4 8.0 0.0 3.0 2 0 0 2 2 2 0 Type III secretion basal body protein I, YscI, HrpB, PscI Apo-VLDL-II PF05418.11 EGC35676.1 - 0.24 12.0 1.8 0.91 10.1 0.0 3.1 4 0 0 4 4 4 0 Apovitellenin I (Apo-VLDL-II) EFP PF01132.20 EGC35676.1 - 0.25 11.4 6.6 1 9.4 0.4 4.1 4 0 0 4 4 4 0 Elongation factor P (EF-P) OB domain bZIP_1 PF00170.21 EGC35677.1 - 0.0031 17.6 2.9 0.0031 17.6 2.9 2.3 2 0 0 2 2 2 1 bZIP transcription factor RasGAP_C PF03836.15 EGC35677.1 - 0.012 15.8 14.6 0.064 13.4 14.6 2.0 1 1 0 1 1 1 0 RasGAP C-terminus Tropomyosin_1 PF12718.7 EGC35677.1 - 0.015 15.5 24.0 0.067 13.4 5.1 2.1 1 1 1 2 2 2 0 Tropomyosin like FPP PF05911.11 EGC35677.1 - 0.029 12.6 15.9 0.033 12.4 15.9 1.1 1 0 0 1 1 1 0 Filament-like plant protein, long coiled-coil Atg14 PF10186.9 EGC35677.1 - 0.046 12.8 13.2 0.058 12.5 13.2 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 HAP1_N PF04849.13 EGC35677.1 - 0.093 11.9 20.5 0.22 10.7 20.5 1.5 1 1 0 1 1 1 0 HAP1 N-terminal conserved region Vfa1 PF08432.10 EGC35677.1 - 0.093 13.1 11.4 0.13 12.5 11.4 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 MCC-bdg_PDZ PF10506.9 EGC35677.1 - 0.1 12.7 9.4 1.3 9.1 2.3 2.3 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome GAS PF13851.6 EGC35677.1 - 0.12 11.7 23.1 0.19 11.1 23.1 1.3 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF641 PF04859.12 EGC35677.1 - 0.42 11.0 18.8 2.4 8.5 3.8 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Fez1 PF06818.15 EGC35677.1 - 0.5 10.8 19.7 2.3 8.7 19.9 1.8 1 1 0 1 1 1 0 Fez1 HAUS5 PF14817.6 EGC35677.1 - 0.67 8.6 16.8 1.5 7.5 16.8 1.5 1 1 0 1 1 1 0 HAUS augmin-like complex subunit 5 MAP70 PF07058.11 EGC35677.1 - 1.1 8.0 17.7 0.019 13.7 7.0 2.0 1 1 1 2 2 2 0 Microtubule-associated protein 70 DUF4988 PF16378.5 EGC35677.1 - 1.1 8.9 5.9 3.4 7.3 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function V_ATPase_I PF01496.19 EGC35677.1 - 1.3 6.9 7.7 1.7 6.5 7.7 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Pro_CA PF00484.19 EGC35677.1 - 2 8.7 6.7 3.8 7.8 6.6 1.5 1 1 0 1 1 1 0 Carbonic anhydrase DUF5320 PF17253.2 EGC35677.1 - 2.4 9.3 9.7 2.7 9.1 1.3 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5320) DUF4201 PF13870.6 EGC35677.1 - 3.6 7.3 25.0 30 4.3 25.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4201) LMBR1 PF04791.16 EGC35677.1 - 4.8 6.0 9.8 6.4 5.6 9.8 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Borrelia_P83 PF05262.11 EGC35677.1 - 5.9 5.3 14.9 7.6 4.9 14.9 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein UPF0242 PF06785.11 EGC35677.1 - 6.9 6.7 23.0 10 6.1 23.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus ALMT PF11744.8 EGC35677.1 - 7.3 5.3 11.5 9.4 4.9 11.5 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF4407 PF14362.6 EGC35677.1 - 7.5 5.8 12.4 11 5.3 12.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EGC35677.1 - 8.9 5.1 22.9 6.2 5.6 17.6 1.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Swi5 PF07061.11 EGC35677.1 - 9.8 6.4 15.1 1.8e+04 -4.1 15.1 2.5 1 1 0 1 1 0 0 Swi5 Pkinase PF00069.25 EGC35678.1 - 1.1e-74 251.1 0.0 2.9e-74 249.8 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35678.1 - 2.5e-53 181.0 0.0 4.6e-53 180.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC35678.1 - 1.9e-06 27.0 0.0 1.9e-06 27.0 0.0 2.7 3 1 0 3 3 3 1 Fungal protein kinase Kinase-like PF14531.6 EGC35678.1 - 8e-05 22.1 0.0 0.00019 20.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC35678.1 - 0.00049 19.5 0.1 0.00092 18.6 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGC35678.1 - 0.027 14.1 1.9 0.036 13.7 0.2 2.0 2 0 0 2 2 2 0 RIO1 family VF530 PF09905.9 EGC35678.1 - 0.11 12.7 0.3 2.3 8.5 0.1 2.7 2 0 0 2 2 2 0 DNA-binding protein VF530 zf-ribbon_3 PF13248.6 EGC35679.1 - 0.017 14.5 2.5 0.034 13.6 2.5 1.5 1 0 0 1 1 1 0 zinc-ribbon domain DUF3278 PF11683.8 EGC35679.1 - 0.09 12.9 1.6 0.41 10.7 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3278) Minor_capsid_1 PF10665.9 EGC35680.1 - 0.11 12.7 0.1 0.11 12.7 0.1 4.8 3 2 1 5 5 5 0 Minor capsid protein RhoGEF PF00621.20 EGC35681.1 - 6.7e-35 121.0 4.9 6.7e-35 121.0 4.9 3.0 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.29 EGC35681.1 - 0.0067 16.9 0.8 0.0067 16.9 0.8 2.9 3 1 0 3 3 3 1 PH domain PH_9 PF15410.6 EGC35681.1 - 0.0095 16.3 1.1 0.0095 16.3 1.1 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain MADF_DNA_bdg PF10545.9 EGC35681.1 - 0.37 11.1 0.0 0.37 11.1 0.0 4.3 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Actin PF00022.19 EGC35682.1 - 3e-152 507.0 0.0 9.6e-152 505.3 0.0 1.6 1 1 0 1 1 1 1 Actin ETRAMP PF09716.10 EGC35684.1 - 0.065 13.3 5.6 0.27 11.3 5.6 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) UCH PF00443.29 EGC35685.1 - 0.00019 21.0 0.3 0.00022 20.8 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.29 EGC35686.1 - 3.7e-07 29.9 0.3 6.4e-07 29.1 0.1 1.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase TRAPP PF04051.16 EGC35688.1 - 2e-41 141.1 0.3 2.7e-41 140.7 0.3 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Brix PF04427.18 EGC35689.1 - 3.3e-32 112.2 0.3 4.4e-32 111.8 0.3 1.2 1 0 0 1 1 1 1 Brix domain PRESAN PF09687.10 EGC35690.1 - 0.33 11.5 9.5 0.9 10.1 9.4 1.7 1 1 0 1 1 1 0 Plasmodium RESA N-terminal APOBEC1 PF18769.1 EGC35691.1 - 0.017 15.4 0.0 0.11 12.8 0.0 2.4 1 0 0 1 1 1 0 APOBEC1 RasGEF PF00617.19 EGC35693.1 - 2.4e-58 197.2 6.7 4.8e-58 196.3 2.0 3.0 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.20 EGC35693.1 - 4.4e-23 81.5 0.6 4.4e-23 81.5 0.6 4.8 4 1 0 4 4 4 1 RasGEF N-terminal motif CH PF00307.31 EGC35693.1 - 3.2e-10 40.1 2.3 6.8e-10 39.1 0.1 2.9 3 0 0 3 3 3 1 Calponin homology (CH) domain Ribosomal_60s PF00428.19 EGC35693.1 - 0.076 13.6 4.2 0.22 12.1 4.2 1.7 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-RING_2 PF13639.6 EGC35694.1 - 6.5e-08 32.8 17.0 1.1e-07 32.0 17.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC35694.1 - 3.8e-07 29.9 14.3 6.2e-07 29.2 14.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC35694.1 - 2.4e-05 24.5 11.8 6.1e-05 23.2 11.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC35694.1 - 3.9e-05 23.4 16.0 7.3e-05 22.5 16.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC35694.1 - 0.00033 20.5 14.1 0.0013 18.5 13.8 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC35694.1 - 0.00097 19.0 18.1 0.002 18.0 18.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC35694.1 - 0.0058 16.7 20.6 0.0069 16.4 20.1 1.4 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC35694.1 - 0.079 12.9 15.8 0.15 12.1 15.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC35694.1 - 0.26 11.4 7.4 0.51 10.4 7.4 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC35694.1 - 1.1 9.0 11.7 1.7 8.3 11.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Asp-B-Hydro_N PF05279.11 EGC35694.1 - 3 7.8 17.0 6.2 6.8 17.0 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-RING_UBOX PF13445.6 EGC35694.1 - 6 7.0 13.8 15 5.7 13.8 1.7 1 0 0 1 1 1 0 RING-type zinc-finger Radical_SAM_C PF16199.5 EGC35695.1 - 3.9e-32 110.1 0.0 7.7e-32 109.2 0.0 1.5 1 0 0 1 1 1 1 Radical_SAM C-terminal domain Radical_SAM PF04055.21 EGC35695.1 - 6.2e-20 72.2 0.1 2.4e-19 70.3 0.0 2.0 2 0 0 2 2 2 1 Radical SAM superfamily Acetyltransf_1 PF00583.25 EGC35695.1 - 2e-11 44.1 0.1 3.5e-11 43.3 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC35695.1 - 1.8e-06 27.9 0.1 4.5e-06 26.6 0.1 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC35695.1 - 0.00048 20.5 0.1 0.001 19.5 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC35695.1 - 0.019 14.9 0.0 0.045 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Glyco_hydro_42 PF02449.15 EGC35695.1 - 0.052 12.9 0.0 0.079 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase Dicty_CTDC PF00526.18 EGC35696.1 - 8.4e-10 38.4 15.7 1.8e-08 34.1 6.3 6.5 6 0 0 6 6 6 2 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC35696.1 - 2.9e-09 36.9 0.0 4.8e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 PA14 domain ATP-synt_J PF04911.12 EGC35698.1 - 0.055 13.1 0.1 0.079 12.6 0.1 1.4 1 0 0 1 1 1 0 ATP synthase j chain HLH PF00010.26 EGC35699.1 - 0.0044 16.9 0.7 0.0069 16.3 0.7 1.3 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Elong-fact-P_C PF09285.11 EGC35699.1 - 0.072 12.9 0.1 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Elongation factor P, C-terminal NADH_dh_m_C1 PF15088.6 EGC35699.1 - 0.17 11.5 0.3 2.7 7.7 0.0 2.2 2 0 0 2 2 2 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial RNB PF00773.19 EGC35700.1 - 2.7e-22 79.5 1.1 2.7e-22 79.5 1.1 4.6 3 2 1 4 4 4 1 RNB domain PhoH PF02562.16 EGC35700.1 - 0.028 13.9 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 PhoH-like protein RsgA_GTPase PF03193.16 EGC35700.1 - 0.032 14.1 0.1 0.082 12.8 0.1 1.6 1 0 0 1 1 1 0 RsgA GTPase DEAD PF00270.29 EGC35700.1 - 0.032 14.0 0.0 0.11 12.2 0.0 2.0 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_30 PF13604.6 EGC35700.1 - 0.088 12.5 0.0 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGC35700.1 - 0.16 11.7 0.0 0.16 11.7 0.0 2.9 3 0 0 3 3 3 0 AAA domain DUF1771 PF08590.10 EGC35701.1 - 5.8e-11 42.6 5.5 5.8e-11 42.6 5.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.21 EGC35701.1 - 4.2e-05 23.8 0.0 0.00012 22.3 0.0 1.8 1 1 0 1 1 1 1 Smr domain zf-C3H1 PF10650.9 EGC35701.1 - 9.6e-05 22.0 6.2 0.00096 18.8 1.2 3.0 2 0 0 2 2 2 1 Putative zinc-finger domain Torus PF16131.5 EGC35701.1 - 0.0031 18.2 1.4 0.0031 18.2 1.4 3.8 3 1 1 4 4 2 1 Torus domain CUE PF02845.16 EGC35701.1 - 0.0096 15.6 0.0 0.027 14.2 0.0 1.8 1 0 0 1 1 1 1 CUE domain zf_CCCH_4 PF18345.1 EGC35701.1 - 0.017 15.2 0.2 0.017 15.2 0.2 5.1 5 1 0 5 5 5 0 Zinc finger domain zf-CCCH_2 PF14608.6 EGC35701.1 - 0.022 15.2 4.1 0.022 15.2 4.1 4.8 4 1 1 5 5 5 0 RNA-binding, Nab2-type zinc finger zf-CCCH PF00642.24 EGC35701.1 - 0.031 14.2 14.9 0.034 14.1 0.2 3.3 2 1 1 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_3 PF15663.5 EGC35701.1 - 0.039 14.2 16.9 0.089 13.0 6.3 3.0 2 1 1 3 3 3 0 Zinc-finger containing family DMA PF03474.14 EGC35701.1 - 0.041 13.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 DMRTA motif zf-CCCH_4 PF18044.1 EGC35701.1 - 0.48 10.3 0.1 0.48 10.3 0.1 3.6 4 1 0 4 4 4 0 CCCH-type zinc finger MMU163 PF17119.5 EGC35701.1 - 0.53 9.4 4.1 0.95 8.6 4.1 1.4 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis Presenilin PF01080.17 EGC35701.1 - 2.1 7.0 7.5 3.4 6.3 7.5 1.3 1 0 0 1 1 1 0 Presenilin Menin PF05053.13 EGC35701.1 - 3.2 6.0 14.0 5.3 5.3 14.0 1.3 1 0 0 1 1 1 0 Menin LMF1 PF06762.14 EGC35702.1 - 5.5e-110 368.5 29.0 1.1e-57 196.1 10.7 3.3 3 1 0 4 4 4 2 Lipase maturation factor Beta-lactamase2 PF13354.6 EGC35703.1 - 0.0011 18.7 0.0 0.0017 18.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase enzyme family LMBR1 PF04791.16 EGC35703.1 - 0.0097 14.9 7.8 0.015 14.2 7.8 1.2 1 0 0 1 1 1 1 LMBR1-like membrane protein GP41 PF00517.17 EGC35703.1 - 0.049 13.5 4.8 0.095 12.6 4.8 1.4 1 0 0 1 1 1 0 Retroviral envelope protein FAM76 PF16046.5 EGC35703.1 - 9.3 5.5 9.8 14 5.0 9.8 1.1 1 0 0 1 1 1 0 FAM76 protein Chromo PF00385.24 EGC35704.1 - 9.1e-15 54.3 2.3 1.1e-14 54.1 2.3 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGC35704.1 - 0.048 13.8 0.1 0.071 13.3 0.1 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Aminotran_5 PF00266.19 EGC35705.1 - 0.0037 16.3 0.0 0.0041 16.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V 2OG-FeII_Oxy_3 PF13640.6 EGC35708.1 - 3.8e-15 56.5 0.0 5.6e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.20 EGC35708.1 - 0.00046 20.6 0.0 0.00071 20.0 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2652 PF10851.8 EGC35708.1 - 0.094 12.8 0.0 0.25 11.5 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2652) SNARE PF05739.19 EGC35709.1 - 1.8e-10 40.6 0.4 3.6e-10 39.7 0.4 1.5 1 0 0 1 1 1 1 SNARE domain Use1 PF09753.9 EGC35709.1 - 1.3e-05 25.1 0.1 1.5e-05 24.8 0.1 1.0 1 0 0 1 1 1 1 Membrane fusion protein Use1 Vip3A_N PF12495.8 EGC35709.1 - 0.05 13.5 0.3 0.064 13.2 0.3 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF1139 PF06599.11 EGC35709.1 - 0.06 12.7 0.3 0.067 12.6 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) ECSCR PF15820.5 EGC35709.1 - 0.13 12.1 0.3 0.22 11.4 0.3 1.4 1 0 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator Mit_KHE1 PF10173.9 EGC35710.1 - 7.1e-43 146.9 4.5 7.1e-43 146.9 4.5 2.1 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related SUIM_assoc PF16619.5 EGC35710.1 - 0.027 14.5 0.2 0.027 14.5 0.2 2.5 2 1 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Mucin PF01456.17 EGC35710.1 - 8.9 6.3 10.3 3.2 7.7 4.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.25 EGC35711.1 - 4.5e-62 209.8 0.0 8.7e-62 208.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35711.1 - 1.1e-44 152.7 0.0 1.8e-44 152.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16_M PF16187.5 EGC35711.1 - 1.1e-42 146.3 2.9 1.1e-42 146.3 2.9 2.2 3 0 0 3 3 3 1 Middle or third domain of peptidase_M16 Peptidase_M16 PF00675.20 EGC35711.1 - 2e-34 118.7 0.0 7.3e-34 116.9 0.0 2.0 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.21 EGC35711.1 - 9.8e-24 84.4 10.1 3.6e-14 53.2 0.4 4.3 3 1 1 4 4 4 2 Peptidase M16 inactive domain Pkinase_fungal PF17667.1 EGC35711.1 - 0.0012 17.7 0.0 0.0012 17.7 0.0 3.1 3 1 0 3 3 3 1 Fungal protein kinase APH PF01636.23 EGC35711.1 - 0.19 11.6 0.0 0.34 10.8 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.7 EGC35712.1 - 2.4e-05 24.1 0.1 5.5e-05 23.0 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC35712.1 - 0.0008 19.2 0.0 0.0024 17.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGC35713.1 - 6e-05 22.9 0.1 0.00014 21.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC35713.1 - 0.0017 18.1 0.0 0.005 16.7 0.0 1.8 1 0 0 1 1 1 1 F-box domain TIG PF01833.24 EGC35714.1 - 4.8e-06 26.6 4.8 0.02 14.9 0.1 3.4 2 1 1 3 3 3 2 IPT/TIG domain TMEM154 PF15102.6 EGC35714.1 - 0.00078 19.4 0.4 0.0018 18.1 0.4 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF4448 PF14610.6 EGC35714.1 - 0.00081 19.2 0.2 0.0023 17.8 0.2 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) DUF4519 PF15012.6 EGC35714.1 - 0.0067 16.6 0.3 0.014 15.6 0.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4519) Syndecan PF01034.20 EGC35714.1 - 0.047 13.6 0.2 0.12 12.3 0.2 1.7 1 0 0 1 1 1 0 Syndecan domain DUF4064 PF13273.6 EGC35714.1 - 0.065 13.5 0.4 0.065 13.5 0.4 2.0 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) DUF5383 PF17355.2 EGC35714.1 - 0.71 10.3 7.9 0.19 12.1 3.8 2.3 2 1 0 2 2 2 0 Family of unknown function (DUF5383) DUF3165 PF11364.8 EGC35715.1 - 0.077 13.4 5.0 0.41 11.0 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) DUF1240 PF06836.12 EGC35715.1 - 0.33 11.5 5.3 0.55 10.8 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) GMP_synt_C PF00958.22 EGC35716.1 - 8.5e-22 77.0 0.0 1.1e-12 47.8 0.0 2.6 2 0 0 2 2 2 2 GMP synthase C terminal domain COMP PF11598.8 EGC35716.1 - 0.016 15.6 0.5 5.6 7.5 0.0 2.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein NAD_synthase PF02540.17 EGC35716.1 - 0.03 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 NAD synthase SART-1 PF03343.13 EGC35717.1 - 1.3e-70 238.7 99.6 3.9e-59 200.8 79.4 2.7 3 1 0 3 3 3 2 SART-1 family CPSF_A PF03178.15 EGC35718.1 - 9.5e-74 248.6 0.3 3.8e-73 246.6 0.1 2.0 2 0 0 2 2 2 1 CPSF A subunit region MMS1_N PF10433.9 EGC35718.1 - 3.3e-27 95.3 7.7 1.7e-24 86.3 0.4 3.2 3 0 0 3 3 3 2 Mono-functional DNA-alkylating methyl methanesulfonate N-term DUF4369 PF14289.6 EGC35718.1 - 1.4 9.5 5.2 0.6 10.6 0.2 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4369) CAP PF00188.26 EGC35719.1 - 9.6e-07 29.7 0.2 2.3e-06 28.5 0.2 1.7 1 0 0 1 1 1 1 Cysteine-rich secretory protein family DUF5529 PF17669.1 EGC35720.1 - 0.034 14.2 0.0 0.048 13.7 0.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5529) Chromo PF00385.24 EGC35721.1 - 2.3e-13 49.8 1.4 6.6e-13 48.4 1.4 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain TFIIA PF03153.13 EGC35721.1 - 0.00098 19.2 30.7 0.0014 18.8 30.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Draxin PF15550.6 EGC35721.1 - 0.1 12.4 20.1 0.15 11.9 20.1 1.2 1 0 0 1 1 1 0 Draxin tRNA_anti-like PF12869.7 EGC35721.1 - 0.37 10.4 7.4 0.25 11.0 4.2 2.3 2 0 0 2 2 2 0 tRNA_anti-like PNISR PF15996.5 EGC35721.1 - 7.9 6.7 36.5 6.1 7.1 13.4 2.2 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR CDC27 PF09507.10 EGC35721.1 - 8.7 5.6 39.2 18 4.6 39.2 1.4 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 Chromo PF00385.24 EGC35722.1 - 2.1e-14 53.1 2.6 2.3e-14 53.0 2.6 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain zf-RING_2 PF13639.6 EGC35723.1 - 1.4e-08 35.0 9.8 2.2e-08 34.3 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC35723.1 - 5e-08 32.7 8.3 8e-08 32.0 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35723.1 - 2.5e-07 30.4 9.6 4.9e-07 29.5 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC35723.1 - 3e-07 30.2 8.1 5e-07 29.5 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC35723.1 - 1.2e-06 28.7 7.1 2.9e-06 27.5 7.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC35723.1 - 0.00063 19.7 4.5 0.0013 18.7 4.5 1.6 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC35723.1 - 0.0068 16.3 7.2 0.017 14.9 7.2 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC35723.1 - 0.015 15.3 9.2 0.027 14.4 9.2 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC35723.1 - 0.015 15.5 9.9 0.057 13.6 9.6 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGC35723.1 - 0.062 13.4 4.1 0.13 12.4 4.1 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DZR PF12773.7 EGC35723.1 - 0.062 13.3 7.3 0.14 12.2 7.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon Zn_ribbon_17 PF17120.5 EGC35723.1 - 0.49 10.1 8.0 0.78 9.4 8.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EGC35723.1 - 0.51 10.2 11.9 12 5.8 11.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 EGC35724.1 - 0.00015 21.3 11.2 0.00063 19.2 11.2 1.9 1 1 0 1 1 1 1 Protein kinase domain DUF3439 PF11921.8 EGC35725.1 - 0.00098 19.1 7.8 0.00098 19.1 7.8 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) DUF1743 PF08489.11 EGC35725.1 - 0.047 13.7 2.6 0.2 11.7 0.6 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF1743) Ank_2 PF12796.7 EGC35725.1 - 0.21 12.2 5.0 4.1 8.1 0.9 4.0 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) Mucin PF01456.17 EGC35725.1 - 0.38 10.7 36.2 1.6 8.7 16.5 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Ank_5 PF13857.6 EGC35725.1 - 7.1 7.1 13.2 38 4.8 0.3 6.0 6 1 1 7 7 7 0 Ankyrin repeats (many copies) Pkinase PF00069.25 EGC35726.1 - 2.1e-51 174.9 0.0 2.5e-51 174.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35726.1 - 5.7e-23 81.5 0.0 9.7e-23 80.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC35726.1 - 0.0087 16.0 0.0 0.036 14.0 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC35726.1 - 0.058 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGC35726.1 - 0.088 12.4 0.0 0.17 11.4 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Ribosomal_S5 PF00333.20 EGC35727.1 - 2.3e-28 98.0 2.6 3.9e-28 97.2 2.6 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.15 EGC35727.1 - 1.3e-24 85.4 0.0 2.3e-24 84.6 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain Phage_tail_NK PF16532.5 EGC35727.1 - 0.16 11.6 0.0 0.26 10.9 0.0 1.2 1 0 0 1 1 1 0 Sf6-type phage tail needle knob or tip of some Caudovirales RPN1_RPN2_N PF17781.1 EGC35728.1 - 3.1e-118 394.7 4.3 4.3e-118 394.2 4.3 1.2 1 0 0 1 1 1 1 RPN1/RPN2 N-terminal domain RPN1_C PF18051.1 EGC35728.1 - 7.4e-29 99.6 1.0 1.3e-28 98.8 0.1 1.8 2 0 0 2 2 2 1 26S proteasome non-ATPase regulatory subunit RPN1 C-terminal PC_rep PF01851.22 EGC35728.1 - 1.8e-18 65.9 24.0 3.1e-05 24.2 0.0 8.4 8 0 0 8 8 8 3 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGC35728.1 - 3e-08 33.9 0.5 0.13 12.7 0.0 4.0 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGC35728.1 - 0.0011 19.0 0.0 6.8 7.2 0.0 3.9 3 0 0 3 3 3 1 HEAT repeat DUF707 PF05212.12 EGC35728.1 - 0.1 11.8 0.0 0.23 10.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF707) HEAT_EZ PF13513.6 EGC35728.1 - 0.12 12.9 2.9 77 3.9 0.1 3.9 2 1 1 3 3 3 0 HEAT-like repeat Utp13 PF08625.11 EGC35728.1 - 0.39 10.6 3.0 0.56 10.1 0.1 2.8 3 0 0 3 3 3 0 Utp13 specific WD40 associated domain CRA PF06589.11 EGC35728.1 - 4.4 7.4 6.9 9.6 6.3 6.9 1.5 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) Ank_4 PF13637.6 EGC35730.1 - 3.8e-06 27.3 0.3 0.00053 20.5 0.0 3.8 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC35730.1 - 0.00017 22.1 1.0 0.027 15.1 0.1 3.9 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC35730.1 - 0.11 13.1 0.3 5.3 7.9 0.0 4.1 4 0 0 4 4 4 0 Ankyrin repeat Complex1_LYR PF05347.15 EGC35732.1 - 2.7e-06 27.3 1.1 5e-06 26.5 1.1 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) GHMP_kinases_N PF00288.26 EGC35733.1 - 0.00024 21.3 0.4 0.00065 19.9 0.4 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain NOC3p PF07540.11 EGC35734.1 - 1e-26 93.2 0.9 1e-26 93.2 0.9 3.5 3 0 0 3 3 3 1 Nucleolar complex-associated protein CBF PF03914.17 EGC35734.1 - 5.7e-18 65.5 0.0 5.7e-18 65.5 0.0 2.8 3 1 0 3 3 3 1 CBF/Mak21 family Swi5 PF07061.11 EGC35735.1 - 4.2e-19 68.4 4.9 7.5e-19 67.6 4.9 1.4 1 0 0 1 1 1 1 Swi5 SCP-1 PF05483.12 EGC35735.1 - 0.00091 17.4 8.6 0.00091 17.4 8.6 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) E2F_CC-MB PF16421.5 EGC35735.1 - 0.0011 19.3 1.7 0.002 18.5 1.7 1.5 1 0 0 1 1 1 1 E2F transcription factor CC-MB domain ZapB PF06005.12 EGC35735.1 - 0.0021 18.5 6.3 0.004 17.6 6.2 1.5 1 1 0 1 1 1 1 Cell division protein ZapB TMF_DNA_bd PF12329.8 EGC35735.1 - 0.0027 17.6 7.5 0.0027 17.6 7.5 2.4 1 1 2 3 3 3 1 TATA element modulatory factor 1 DNA binding SLIDE PF09111.10 EGC35735.1 - 0.0069 16.4 1.7 0.014 15.5 1.7 1.6 1 0 0 1 1 1 1 SLIDE LPP PF04728.13 EGC35735.1 - 0.0092 16.3 1.9 0.017 15.5 1.6 1.7 1 1 0 1 1 1 1 Lipoprotein leucine-zipper APG6_N PF17675.1 EGC35735.1 - 0.012 16.1 8.8 0.023 15.2 8.7 1.6 1 1 1 2 2 2 0 Apg6 coiled-coil region SKA2 PF16740.5 EGC35735.1 - 0.013 15.3 3.7 0.021 14.6 3.7 1.6 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 2 GrpE PF01025.19 EGC35735.1 - 0.022 14.4 6.6 0.024 14.3 6.1 1.4 1 1 0 1 1 1 0 GrpE GAS PF13851.6 EGC35735.1 - 0.027 13.8 11.4 0.033 13.5 11.4 1.2 1 0 0 1 1 1 0 Growth-arrest specific micro-tubule binding Laminin_II PF06009.12 EGC35735.1 - 0.032 14.3 2.1 0.048 13.7 1.6 1.4 1 1 0 1 1 1 0 Laminin Domain II MCU PF04678.13 EGC35735.1 - 0.041 14.0 0.6 0.05 13.7 0.6 1.3 1 0 0 1 1 1 0 Mitochondrial calcium uniporter HycH PF07450.11 EGC35735.1 - 0.043 14.2 1.3 2 8.8 0.0 2.1 1 1 1 2 2 2 0 Formate hydrogenlyase maturation protein HycH Med30 PF11315.8 EGC35735.1 - 0.054 13.7 6.2 0.036 14.3 3.5 1.8 1 1 1 2 2 2 0 Mediator complex subunit 30 DUF4200 PF13863.6 EGC35735.1 - 0.056 13.8 10.0 0.14 12.6 4.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF948 PF06103.11 EGC35735.1 - 0.057 13.7 0.5 0.094 13.0 0.5 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) FapA PF03961.13 EGC35735.1 - 0.058 12.0 9.7 0.076 11.6 9.7 1.2 1 0 0 1 1 1 0 Flagellar Assembly Protein A Cauli_AT PF03233.13 EGC35735.1 - 0.07 13.1 5.3 0.1 12.5 5.3 1.3 1 0 0 1 1 1 0 Aphid transmission protein Snapin_Pallidin PF14712.6 EGC35735.1 - 0.072 13.5 5.5 0.14 12.6 4.8 1.7 1 1 0 1 1 1 0 Snapin/Pallidin TRPM_tetra PF16519.5 EGC35735.1 - 0.083 13.0 2.4 2.6 8.2 1.7 2.3 1 1 1 2 2 2 0 Tetramerisation domain of TRPM PI3K_P85_iSH2 PF16454.5 EGC35735.1 - 0.094 12.3 9.5 0.19 11.3 9.5 1.6 1 1 0 1 1 1 0 Phosphatidylinositol 3-kinase regulatory subunit P85 inter-SH2 domain FlxA PF14282.6 EGC35735.1 - 0.097 12.7 7.1 3.5 7.7 7.1 2.4 1 1 0 1 1 1 0 FlxA-like protein HAUS6_N PF14661.6 EGC35735.1 - 0.15 11.7 3.4 0.16 11.5 3.4 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF4407 PF14362.6 EGC35735.1 - 0.15 11.4 2.5 0.15 11.4 2.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF4140 PF13600.6 EGC35735.1 - 0.19 12.2 3.9 0.43 11.1 3.9 1.7 1 1 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) SlyX PF04102.12 EGC35735.1 - 0.42 11.2 5.7 1.2 9.8 4.7 2.0 1 1 1 2 2 2 0 SlyX DivIC PF04977.15 EGC35735.1 - 0.46 10.3 6.8 0.68 9.7 5.8 1.8 1 1 0 1 1 1 0 Septum formation initiator FliD_N PF02465.18 EGC35735.1 - 0.59 10.9 3.5 26 5.6 3.4 2.3 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus TMPIT PF07851.13 EGC35735.1 - 0.61 9.3 3.3 0.64 9.2 3.3 1.2 1 0 0 1 1 1 0 TMPIT-like protein LMBR1 PF04791.16 EGC35735.1 - 5.4 5.8 5.4 5.4 5.8 5.4 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF2678 PF10856.8 EGC35736.1 - 0.011 15.6 3.1 1.8 8.5 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) EGF_2 PF07974.13 EGC35736.1 - 2.6 8.5 12.5 8.4 6.9 12.5 1.9 1 0 0 1 1 1 0 EGF-like domain DUF2678 PF10856.8 EGC35737.1 - 0.063 13.2 0.3 0.2 11.6 0.3 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2678) EGF_2 PF07974.13 EGC35737.1 - 5.7 7.4 12.2 1.3 9.5 8.5 1.9 2 0 0 2 2 2 0 EGF-like domain AMP-binding PF00501.28 EGC35738.1 - 5.6e-88 295.4 0.9 3.3e-87 292.8 0.1 2.3 2 0 0 2 2 2 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.10 EGC35738.1 - 0.016 15.3 0.0 0.048 13.7 0.0 1.8 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Cas2CT1978) Pyr_redox_2 PF07992.14 EGC35739.1 - 3e-48 164.6 0.0 3.8e-48 164.2 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC35739.1 - 2.3e-10 40.9 0.1 4.9e-07 30.2 0.1 3.6 4 1 0 4 4 4 2 Pyridine nucleotide-disulphide oxidoreductase SoPB_HTH PF18090.1 EGC35739.1 - 0.17 12.1 0.0 0.56 10.4 0.0 1.8 2 0 0 2 2 2 0 Centromere-binding protein HTH domain Proteasome PF00227.26 EGC35740.1 - 9e-47 159.0 0.1 1.1e-46 158.7 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Band_7 PF01145.25 EGC35741.1 - 0.00055 20.0 10.8 0.0052 16.8 10.8 2.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Glyco_hydro_7 PF00840.20 EGC35742.1 - 2.5e-202 672.4 11.3 2.8e-202 672.2 11.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 DUF4501 PF14946.6 EGC35742.1 - 0.13 12.3 0.7 0.37 10.9 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4501) Sdh5 PF03937.16 EGC35743.1 - 1.6e-25 88.8 0.3 2.1e-25 88.4 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase zinc_ribbon_15 PF17032.5 EGC35744.1 - 0.12 13.1 7.8 4.8 8.0 0.3 4.0 3 0 0 3 3 3 0 zinc-ribbon family RSRP PF17069.5 EGC35744.1 - 5 6.6 67.8 0.025 14.2 50.7 3.4 3 0 0 3 3 3 0 Arginine/Serine-Rich protein 1 DUF5094 PF17015.5 EGC35745.1 - 1.2e-05 25.4 15.4 1.2e-05 25.4 15.4 5.9 1 1 2 4 4 4 1 Domain of unknown function (DUF5094) TPR_MLP1_2 PF07926.12 EGC35745.1 - 0.0091 16.1 22.0 0.0091 16.1 22.0 6.0 2 1 4 6 6 6 2 TPR/MLP1/MLP2-like protein Arabino_trans_C PF14896.6 EGC35745.1 - 0.61 9.0 5.9 1.3 8.0 5.9 1.5 1 0 0 1 1 1 0 EmbC C-terminal domain gp37_C PF12604.8 EGC35746.1 - 0.014 15.1 0.3 0.021 14.5 0.3 1.3 1 0 0 1 1 1 0 Tail fibre protein gp37 C terminal DUF3912 PF13051.6 EGC35746.1 - 0.11 12.8 0.1 0.32 11.3 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3912) FUN14 PF04930.15 EGC35747.1 - 0.27 11.7 4.1 0.52 10.8 0.1 2.6 2 1 1 3 3 3 0 FUN14 family Orf78 PF06024.12 EGC35747.1 - 5.7 7.3 9.8 5.6 7.3 0.6 2.7 2 1 1 3 3 3 0 Orf78 (ac78) Ribosomal_S8 PF00410.19 EGC35749.1 - 1.9e-18 66.6 0.1 3.6e-18 65.7 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein S8 BBS2_Mid PF14783.6 EGC35750.1 - 9.4e-08 32.1 2.2 9.9e-06 25.6 0.2 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Autotransporter PF03797.19 EGC35750.1 - 0.074 12.7 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Autotransporter beta-domain Methyltransf_12 PF08242.12 EGC35750.1 - 0.53 11.0 4.0 1 10.2 0.9 2.8 2 0 0 2 2 2 0 Methyltransferase domain Rap_GAP PF02145.15 EGC35751.1 - 1.3e-67 226.9 0.1 3.6e-67 225.5 0.1 1.8 1 0 0 1 1 1 1 Rap/ran-GAP Mucin PF01456.17 EGC35751.1 - 0.0099 15.9 10.8 0.0099 15.9 10.8 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein Focadhesin PF11229.8 EGC35751.1 - 0.013 13.8 0.1 0.02 13.1 0.1 1.2 1 0 0 1 1 1 0 Focadhesin DUF3439 PF11921.8 EGC35751.1 - 0.43 10.6 10.3 1.2 9.1 10.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NST1 PF13945.6 EGC35751.1 - 1.8 8.7 17.5 0.037 14.1 2.5 3.0 3 0 0 3 3 3 0 Salt tolerance down-regulator DEAD PF00270.29 EGC35752.1 - 4.9e-19 68.8 4.2 5e-19 68.7 0.7 2.5 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC35752.1 - 1.4e-08 35.0 1.8 3.2e-08 33.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DUF3837 PF12939.7 EGC35752.1 - 6.1 7.3 10.4 2.2 8.7 6.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3837) DUF962 PF06127.11 EGC35753.1 - 2.1e-35 120.7 0.5 2.4e-35 120.5 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) MerC PF03203.14 EGC35753.1 - 0.071 13.6 0.2 0.08 13.4 0.2 1.1 1 0 0 1 1 1 0 MerC mercury resistance protein Ig_mannosidase PF17753.1 EGC35754.1 - 3.9e-10 39.3 0.0 1.1e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 Ig-fold domain Glyco_hydro_2 PF00703.21 EGC35754.1 - 6.1e-08 33.3 0.1 6.1e-08 33.3 0.1 3.1 4 0 0 4 4 4 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.17 EGC35754.1 - 0.01 15.0 0.3 0.052 12.7 0.3 2.0 1 1 0 1 1 1 0 Glycosyl hydrolases family 2, TIM barrel domain DIOX_N PF14226.6 EGC35755.1 - 8.2e-07 29.8 0.0 1.9e-06 28.6 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal Aldedh PF00171.22 EGC35756.1 - 8.5e-121 403.7 0.0 1.1e-120 403.3 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.14 EGC35756.1 - 3e-05 23.3 0.2 4.5e-05 22.7 0.2 1.2 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) Erf4 PF10256.9 EGC35757.1 - 3.8e-11 43.1 5.8 4.7e-06 26.7 0.1 2.4 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family Chordopox_A13L PF05961.11 EGC35757.1 - 0.08 13.2 1.9 0.21 11.8 0.3 2.4 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF3430 PF11912.8 EGC35758.1 - 2.9e-13 50.4 31.1 4e-13 49.9 31.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) MFS_1 PF07690.16 EGC35759.1 - 1.8e-48 165.3 35.1 1.7e-47 162.1 24.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily BPD_transp_2 PF02653.16 EGC35761.1 - 0.27 10.4 0.0 0.37 9.9 0.0 1.1 1 0 0 1 1 1 0 Branched-chain amino acid transport system / permease component PRP1_N PF06424.12 EGC35761.1 - 7.5 6.9 13.9 1.3 9.4 9.4 1.9 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal FNIP PF05725.12 EGC35762.1 - 1.8e-47 159.2 44.8 3e-13 49.7 2.6 9.1 7 2 0 8 8 8 7 FNIP Repeat FNIP PF05725.12 EGC35763.1 - 2.5e-96 315.6 41.3 5.9e-17 61.6 1.3 7.9 5 2 4 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 EGC35763.1 - 0.0097 16.1 12.4 64 3.9 0.0 7.5 5 3 2 7 7 7 0 Protein of unknown function (DUF1769) Phage_min_tail PF05939.13 EGC35763.1 - 0.069 13.5 1.2 37 4.7 0.0 4.3 3 3 5 8 8 8 0 Phage minor tail protein Dickkopf_N PF04706.12 EGC35764.1 - 6.5e-05 23.3 75.2 0.0013 19.1 17.6 6.1 4 1 1 5 5 5 3 Dickkopf N-terminal cysteine-rich region EB PF01683.18 EGC35764.1 - 0.016 15.5 7.6 0.016 15.5 7.6 8.0 3 2 4 7 7 7 0 EB module DIL PF01843.19 EGC35765.1 - 8.3e-22 77.4 0.1 8.3e-22 77.4 0.1 2.9 3 0 0 3 3 3 1 DIL domain NT-C2 PF10358.9 EGC35765.1 - 6.4e-18 64.9 2.4 1.6e-17 63.6 2.4 1.7 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DUF4148 PF13663.6 EGC35765.1 - 0.025 14.7 0.9 0.94 9.7 0.2 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4148) SlyX PF04102.12 EGC35765.1 - 0.86 10.3 58.7 0.29 11.8 6.5 8.7 5 2 4 9 9 9 0 SlyX LRR_6 PF13516.6 EGC35766.1 - 3.3e-07 29.8 43.7 0.31 11.2 0.1 14.4 16 0 0 16 16 16 4 Leucine Rich repeat IstB_IS21 PF01695.17 EGC35766.1 - 0.0026 17.5 0.0 0.007 16.1 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein LRR_4 PF12799.7 EGC35766.1 - 0.16 12.5 0.0 0.06 13.8 0.4 13.3 10 3 2 13 13 13 0 Leucine Rich repeats (2 copies) MsyB PF13984.6 EGC35766.1 - 0.21 11.9 1.4 0.71 10.2 1.4 1.9 1 0 0 1 1 1 0 MsyB protein DUF3439 PF11921.8 EGC35766.1 - 3.1 7.8 19.6 0.47 10.4 7.3 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) WD40 PF00400.32 EGC35768.1 - 4.2e-25 87.5 13.4 4.5e-09 36.8 0.2 7.0 7 0 0 7 7 7 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35768.1 - 4.8e-12 46.0 3.6 0.00019 21.6 0.1 5.6 2 2 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC35768.1 - 0.00031 20.2 5.3 0.00031 20.2 5.3 3.1 3 1 1 4 4 4 1 WD40-like domain MMU163 PF17119.5 EGC35768.1 - 0.01 15.0 0.8 0.01 15.0 0.8 1.8 2 0 0 2 2 2 0 Mitochondrial protein up-regulated during meiosis IMUP PF15761.5 EGC35768.1 - 0.28 11.9 3.1 0.78 10.5 3.1 1.7 1 0 0 1 1 1 0 Immortalisation up-regulated protein XhlA PF10779.9 EGC35768.1 - 9.1 6.6 9.0 27 5.0 9.0 1.8 1 0 0 1 1 1 0 Haemolysin XhlA FNIP PF05725.12 EGC35769.1 - 6.5e-26 90.2 76.7 5.8e-06 26.4 1.4 12.3 10 2 2 12 12 12 8 FNIP Repeat RRM_1 PF00076.22 EGC35769.1 - 1.3e-07 31.4 0.1 4.4e-07 29.6 0.1 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Lipoxygenase PF00305.19 EGC35771.1 - 7e-49 166.9 0.5 9.6e-49 166.4 0.5 1.1 1 0 0 1 1 1 1 Lipoxygenase HATPase_c PF02518.26 EGC35772.1 - 1.5e-27 96.3 0.1 3.8e-27 95.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC35772.1 - 6e-18 65.0 0.2 1.6e-17 63.7 0.2 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGC35772.1 - 4.4e-11 42.6 0.0 1.1e-10 41.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGC35772.1 - 1.3e-06 28.3 0.0 4.7e-06 26.5 0.0 2.0 1 0 0 1 1 1 1 PAS domain PAS_9 PF13426.7 EGC35772.1 - 0.0044 17.3 0.0 0.053 13.8 0.0 3.0 2 1 0 2 2 2 1 PAS domain PAS PF00989.25 EGC35772.1 - 0.0049 16.8 0.0 0.18 11.8 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.10 EGC35772.1 - 0.057 13.7 0.0 0.28 11.4 0.0 2.1 1 1 0 1 1 1 0 PAS fold DUF2527 PF10736.9 EGC35772.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF2627) Pkinase PF00069.25 EGC35773.1 - 2.7e-10 40.1 0.5 2.7e-10 40.1 0.5 2.2 2 1 0 2 2 2 1 Protein kinase domain RIO1 PF01163.22 EGC35773.1 - 2e-09 37.3 0.1 6.1e-09 35.7 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.17 EGC35773.1 - 8.8e-08 31.7 0.2 1.7e-07 30.8 0.2 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC35773.1 - 2.3e-07 30.4 0.0 1.1e-06 28.2 0.0 2.2 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC35773.1 - 4.8e-06 26.7 0.0 0.00039 20.4 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family EcKinase PF02958.20 EGC35773.1 - 0.00092 18.6 1.4 0.0029 17.0 0.1 2.5 3 0 0 3 3 3 1 Ecdysteroid kinase DUF2433 PF10360.9 EGC35773.1 - 0.06 13.5 0.9 11 6.1 0.2 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2433) Peptidase_M3_N PF08439.10 EGC35773.1 - 0.067 13.5 0.3 15 6.0 0.0 3.1 3 0 0 3 3 3 0 Oligopeptidase F Zn_clus PF00172.18 EGC35775.1 - 4.7e-05 23.4 12.6 8.3e-05 22.6 12.6 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.17 EGC35776.1 - 1.5e-104 349.9 27.8 3.6e-74 249.9 12.6 2.0 1 1 1 2 2 2 2 Presenilin Synaptobrevin PF00957.21 EGC35777.1 - 2.2e-10 40.2 0.7 3.9e-10 39.4 0.7 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.6 EGC35777.1 - 0.00022 21.2 0.0 0.00036 20.5 0.0 1.3 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gp-FAR-1 PF05823.12 EGC35777.1 - 0.0034 17.7 1.0 0.0048 17.2 1.0 1.3 1 0 0 1 1 1 1 Nematode fatty acid retinoid binding protein (Gp-FAR-1) ANKH PF07260.11 EGC35777.1 - 0.17 11.0 0.0 0.22 10.7 0.0 1.1 1 0 0 1 1 1 0 Progressive ankylosis protein (ANKH) RNA_pol_L_2 PF13656.6 EGC35778.1 - 1.5e-28 98.4 0.0 1.8e-28 98.1 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.24 EGC35778.1 - 4.4e-12 45.3 0.0 6.6e-12 44.7 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Meleagrin PF08189.11 EGC35779.1 - 0.024 14.3 0.3 0.058 13.1 0.3 1.6 1 0 0 1 1 1 0 Meleagrin/Cygnin family AAR2 PF05282.11 EGC35779.1 - 0.16 11.4 6.5 0.21 11.0 6.5 1.2 1 0 0 1 1 1 0 AAR2 protein eIF_4EBP PF05456.11 EGC35779.1 - 0.4 10.6 8.9 0.16 11.9 5.3 2.1 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) PBP1_TM PF14812.6 EGC35779.1 - 0.52 10.7 5.7 1.1 9.7 5.7 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDK5_activator PF03261.15 EGC35779.1 - 1.5 8.3 29.1 1.9 8.0 29.1 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein EIIBC-GUT_N PF03612.14 EGC35779.1 - 1.6 8.4 6.0 3.1 7.5 6.0 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus zf-TRM13_CCCH PF11722.8 EGC35779.1 - 1.6 8.5 8.6 4.6 7.1 0.1 3.3 3 2 0 3 3 3 0 CCCH zinc finger in TRM13 protein CNDH2_C PF16858.5 EGC35780.1 - 4.2e-54 184.4 1.4 4.2e-54 184.4 1.4 4.1 4 0 0 4 4 4 1 Condensin II complex subunit CAP-H2 or CNDH2, C-term CNDH2_N PF06278.11 EGC35780.1 - 1.7e-41 141.0 1.5 1.7e-41 141.0 1.5 5.7 7 1 1 8 8 8 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal DDE_Tnp_1 PF01609.21 EGC35780.1 - 0.82 9.3 6.7 0.21 11.2 2.8 2.1 2 0 0 2 2 2 0 Transposase DDE domain Pho88 PF10032.9 EGC35780.1 - 8.7 5.6 8.7 0.18 11.0 1.2 2.1 2 0 0 2 2 2 0 Phosphate transport (Pho88) WD40 PF00400.32 EGC35781.1 - 1.4e-19 70.0 19.9 0.00087 20.1 0.0 6.5 6 1 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35781.1 - 1.7e-09 37.8 6.5 0.0024 18.1 0.5 4.4 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC35781.1 - 0.0095 14.9 1.7 5.7 5.8 0.0 3.4 2 1 1 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGC35781.1 - 0.0099 15.9 0.2 0.8 9.8 0.1 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region CBM49 PF09478.10 EGC35782.1 - 7.9e-34 115.8 22.7 1.9e-13 50.5 3.5 3.3 3 0 0 3 3 3 3 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGC35782.1 - 2.8e-10 40.4 13.2 1.4e-05 25.3 1.4 3.2 3 0 0 3 3 3 3 Cellulose binding domain Imm26 PF15428.6 EGC35782.1 - 0.11 12.7 0.8 0.29 11.4 0.4 1.9 2 0 0 2 2 2 0 Immunity protein 26 BNR PF02012.20 EGC35782.1 - 0.49 10.6 3.8 23 5.6 0.0 4.1 4 0 0 4 4 4 0 BNR/Asp-box repeat DHR-2 PF06920.13 EGC35783.1 - 1.2e-75 255.2 16.1 5.3e-75 253.1 16.0 2.1 1 1 0 1 1 1 1 Dock homology region 2 DOCK_N PF16172.5 EGC35783.1 - 8.3e-42 143.4 1.9 4.2e-27 95.1 0.1 3.1 3 0 0 3 3 3 2 DOCK N-terminus DOCK-C2 PF14429.6 EGC35783.1 - 5.1e-36 124.3 0.8 2e-35 122.4 0.2 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3430 PF11912.8 EGC35784.1 - 9.4e-17 61.8 23.4 1e-16 61.6 23.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) TMEM214 PF10151.9 EGC35785.1 - 4.6e-09 35.3 39.0 1.3e-08 33.8 37.4 2.3 1 1 1 2 2 2 1 TMEM214, C-terminal, caspase 4 activator CAF-1_p150 PF11600.8 EGC35785.1 - 0.0095 15.6 14.9 0.0095 15.6 14.9 2.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDRGK PF09756.9 EGC35785.1 - 6.1 6.4 31.7 2.1 7.9 15.6 2.5 2 0 0 2 2 2 0 DDRGK domain WD40 PF00400.32 EGC35786.1 - 1.1e-08 35.6 0.0 3.8e-07 30.7 0.0 3.7 3 0 0 3 3 3 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.14 EGC35786.1 - 1.9e-06 27.2 2.8 0.025 13.6 0.8 3.1 3 0 0 3 3 3 2 Coatomer WD associated region DUF5341 PF17276.2 EGC35786.1 - 0.0053 16.9 2.0 0.08 13.1 0.3 2.6 2 0 0 2 2 2 1 Family of unknown function (DUF5341) ANAPC4_WD40 PF12894.7 EGC35786.1 - 0.013 15.8 0.0 0.5 10.7 0.0 3.3 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain NARG2_C PF10505.9 EGC35787.1 - 1.3e-25 90.2 0.2 2.7e-25 89.2 0.2 1.4 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus zf-CCCH PF00642.24 EGC35787.1 - 0.005 16.7 0.4 0.0097 15.8 0.4 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGC35787.1 - 0.018 15.1 0.9 0.018 15.1 0.9 2.3 2 0 0 2 2 2 0 Zinc finger domain Torus PF16131.5 EGC35787.1 - 0.037 14.7 0.3 0.037 14.7 0.3 5.3 5 1 1 6 6 6 0 Torus domain PTPLA PF04387.14 EGC35788.1 - 6.4e-55 185.4 6.5 6.4e-55 185.4 6.5 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA dsDNA_bind PF01984.20 EGC35789.1 - 6.9e-28 97.1 9.7 7.5e-28 97.0 9.7 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain MDD_C PF18376.1 EGC35790.1 - 2.9e-69 232.6 0.2 4.4e-69 232.0 0.2 1.3 1 0 0 1 1 1 1 Mevalonate 5-diphosphate decarboxylase C-terminal domain GHMP_kinases_N PF00288.26 EGC35790.1 - 1.3e-06 28.5 1.9 3.3e-06 27.2 1.7 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain Tub_N PF16322.5 EGC35790.1 - 0.041 14.3 0.1 0.065 13.6 0.1 1.2 1 0 0 1 1 1 0 Tubby N-terminal Pkinase PF00069.25 EGC35791.1 - 9e-43 146.5 0.0 1.1e-42 146.2 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35791.1 - 4e-20 72.2 0.0 4.7e-20 71.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC35791.1 - 0.0013 18.2 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 2 Kinase-like Lipase_3 PF01764.25 EGC35792.1 - 3.9e-18 65.7 0.0 1e-17 64.3 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) ANF_receptor PF01094.28 EGC35793.1 - 6.3e-45 153.8 0.0 8.9e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.22 EGC35793.1 - 1e-42 146.5 25.1 1.7e-42 145.8 25.1 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.6 EGC35793.1 - 2.2e-16 60.5 0.0 3.6e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein Na_K-ATPase PF00287.18 EGC35793.1 - 0.026 13.7 0.1 0.047 12.9 0.1 1.3 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain Cpn60_TCP1 PF00118.24 EGC35794.1 - 2.1e-153 511.5 11.4 2.4e-153 511.3 11.4 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.12 EGC35794.1 - 0.019 15.3 0.1 0.045 14.1 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1132) Dus PF01207.17 EGC35795.1 - 3e-73 246.6 0.0 3.6e-73 246.4 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) DUF561 PF04481.12 EGC35795.1 - 0.022 14.0 0.0 0.038 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.17 EGC35795.1 - 0.048 13.0 0.1 0.2 11.0 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase His_biosynth PF00977.21 EGC35795.1 - 0.14 11.6 0.0 0.3 10.5 0.0 1.5 2 0 0 2 2 2 0 Histidine biosynthesis protein TPR_12 PF13424.6 EGC35796.1 - 0.00016 21.9 0.2 0.063 13.6 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC35796.1 - 0.019 15.0 3.0 9.5 6.6 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGC35796.1 - 0.03 13.8 0.0 0.11 11.9 0.0 2.0 1 0 0 1 1 1 0 SHNi-TPR TPR_1 PF00515.28 EGC35796.1 - 0.069 13.0 2.7 1.8 8.5 0.3 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGC35796.1 - 0.3 11.2 10.8 0.29 11.2 1.1 3.2 3 1 0 3 3 3 0 MIT (microtubule interacting and transport) domain TPR_8 PF13181.6 EGC35796.1 - 0.51 10.7 6.5 14 6.2 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Allexi_40kDa PF05549.11 EGC35796.1 - 0.72 9.3 5.0 0.12 11.9 0.3 2.0 2 0 0 2 2 2 0 Allexivirus 40kDa protein FSA_C PF10479.9 EGC35796.1 - 0.88 7.6 5.2 1.3 7.1 5.2 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus SSP160 PF06933.11 EGC35796.1 - 3.6 5.7 15.7 5.3 5.1 15.7 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGC35796.1 - 5.7 6.9 12.0 16 5.4 12.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TIM21 PF08294.11 EGC35797.1 - 0.00026 20.9 0.0 0.00051 19.9 0.0 1.5 1 0 0 1 1 1 1 TIM21 Mad3_BUB1_I PF08311.12 EGC35797.1 - 0.00052 20.0 0.6 0.43 10.6 0.3 3.3 2 1 1 3 3 3 2 Mad3/BUB1 homology region 1 Endostatin PF06482.11 EGC35797.1 - 0.077 12.4 0.5 0.15 11.5 0.5 1.3 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF3899 PF13038.6 EGC35797.1 - 0.16 12.5 3.3 1.5 9.4 0.0 3.3 2 2 1 4 4 4 0 Domain of unknown function (DUF3899) DUF1206 PF06724.11 EGC35798.1 - 4.6e-16 58.6 20.1 4.8e-05 23.4 1.7 3.2 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF3439 PF11921.8 EGC35798.1 - 6.5 6.7 10.8 49 3.9 11.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Myb_DNA-binding PF00249.31 EGC35799.1 - 1.2e-29 102.2 13.5 2.7e-11 43.5 0.9 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC35799.1 - 2.2e-23 82.3 17.0 2.9e-11 43.4 1.1 3.6 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.10 EGC35799.1 - 2.7e-07 30.6 7.6 0.0095 16.0 0.3 3.7 1 1 3 4 4 4 3 SLIDE Nore1-SARAH PF16517.5 EGC35799.1 - 0.0037 17.1 1.5 1.8 8.6 0.1 3.6 3 0 0 3 3 3 1 Novel Ras effector 1 C-terminal SARAH (Sav/Rassf/Hpo) domain DAO_C PF16901.5 EGC35799.1 - 0.046 13.6 0.4 8.6 6.2 0.1 2.2 1 1 1 2 2 2 0 C-terminal domain of alpha-glycerophosphate oxidase DUF4177 PF13783.6 EGC35799.1 - 0.057 13.7 0.9 0.93 9.8 0.1 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4177) SANT_DAMP1_like PF16282.5 EGC35799.1 - 0.068 13.4 12.0 0.79 10.0 0.4 3.8 2 1 2 4 4 4 0 SANT/Myb-like domain of DAMP1 TMEM154 PF15102.6 EGC35800.1 - 0.017 15.0 0.8 0.038 13.9 0.8 1.5 1 0 0 1 1 1 0 TMEM154 protein family SR-25 PF10500.9 EGC35800.1 - 0.97 9.0 3.2 1.3 8.6 0.3 2.0 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DASH_Dad2 PF08654.10 EGC35801.1 - 0.055 13.9 0.1 0.084 13.3 0.1 1.4 1 0 0 1 1 1 0 DASH complex subunit Dad2 FliD_N PF02465.18 EGC35801.1 - 0.073 13.8 3.2 0.47 11.2 2.1 2.3 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Myotub-related PF06602.14 EGC35806.1 - 1.8e-125 418.5 0.1 3.9e-125 417.4 0.1 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase PF00102.27 EGC35806.1 - 0.001 18.7 0.6 0.038 13.6 0.0 2.9 2 1 1 3 3 3 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGC35806.1 - 0.097 12.6 0.0 0.35 10.8 0.0 1.9 2 0 0 2 2 2 0 Tyrosine phosphatase family DDHD PF02862.17 EGC35806.1 - 3.8 7.6 14.5 0.068 13.3 2.0 2.4 2 1 0 2 2 2 0 DDHD domain IMPDH PF00478.25 EGC35807.1 - 5.1e-135 449.9 3.9 5.9e-135 449.7 3.9 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.28 EGC35807.1 - 5.6e-13 49.1 0.2 2.6e-06 27.8 0.0 2.6 2 0 0 2 2 2 2 CBS domain NMO PF03060.15 EGC35807.1 - 2e-07 30.8 0.2 3.8e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.18 EGC35807.1 - 2.3e-06 26.9 0.1 1.9e-05 23.9 0.2 2.1 2 0 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.21 EGC35807.1 - 0.00058 19.4 0.9 0.0038 16.7 0.9 2.1 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.14 EGC35807.1 - 0.00068 19.0 0.6 0.0047 16.3 0.2 2.1 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG PcrB PF01884.17 EGC35807.1 - 0.01 15.3 2.6 2 7.8 0.0 3.6 4 0 0 4 4 4 0 PcrB family Glu_synthase PF01645.17 EGC35807.1 - 0.025 13.7 0.3 0.054 12.6 0.3 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase DHO_dh PF01180.21 EGC35807.1 - 0.029 13.6 1.1 0.062 12.5 0.3 1.9 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase B12-binding PF02310.19 EGC35807.1 - 0.062 13.3 0.1 0.12 12.4 0.1 1.4 1 0 0 1 1 1 0 B12 binding domain DUF561 PF04481.12 EGC35807.1 - 0.15 11.2 1.4 0.48 9.5 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Pkinase_Tyr PF07714.17 EGC35808.1 - 4.5e-54 183.5 0.1 7.7e-54 182.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35808.1 - 2.3e-51 174.7 0.1 5.9e-51 173.4 0.1 1.7 1 0 0 1 1 1 1 Protein kinase domain RA PF00788.23 EGC35808.1 - 2.5e-05 24.8 0.8 0.047 14.3 0.0 3.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain WD40 PF00400.32 EGC35809.1 - 1.1e-26 92.6 5.6 1.3e-06 29.0 0.0 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat Sof1 PF04158.14 EGC35809.1 - 2.9e-22 78.7 5.7 2.9e-22 78.7 5.7 1.9 2 0 0 2 2 2 1 Sof1-like domain ANAPC4_WD40 PF12894.7 EGC35809.1 - 7.9e-06 26.1 0.0 0.46 10.8 0.0 4.3 2 1 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain Cytochrom_D1 PF02239.16 EGC35809.1 - 0.009 14.6 0.0 0.66 8.4 0.0 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain Coatomer_WDAD PF04053.14 EGC35809.1 - 0.03 13.4 0.2 0.078 12.0 0.1 1.7 1 1 0 1 1 1 0 Coatomer WD associated region Pkinase PF00069.25 EGC35810.1 - 5.4e-53 180.0 0.2 5.4e-53 180.0 0.2 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35810.1 - 1.9e-20 73.3 0.0 1.9e-20 73.3 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Velvet PF11754.8 EGC35810.1 - 0.0019 18.2 2.7 0.0019 18.2 2.7 3.6 2 1 0 2 2 2 1 Velvet factor APH PF01636.23 EGC35810.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family TFIIA PF03153.13 EGC35810.1 - 0.16 11.9 71.6 0.018 15.0 33.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit ABC2_membrane_2 PF12679.7 EGC35810.1 - 0.37 10.0 0.7 0.55 9.5 0.7 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Asparaginase_2 PF01112.18 EGC35810.1 - 0.39 9.7 3.5 1.1 8.2 3.5 1.7 1 0 0 1 1 1 0 Asparaginase EMC3_TMCO1 PF01956.16 EGC35810.1 - 0.72 9.6 9.3 1.9 8.2 9.3 1.7 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like PepSY_TM PF03929.16 EGC35810.1 - 1.3 8.6 4.6 2.6 7.7 4.6 1.4 1 0 0 1 1 1 0 PepSY-associated TM region SGL PF08450.12 EGC35811.1 - 3.2e-75 252.9 0.2 3.7e-75 252.7 0.2 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 EGC35811.1 - 0.0034 17.4 2.6 2.6 8.6 0.0 3.8 3 0 0 3 3 3 2 Two component regulator propeller VCBS PF13517.6 EGC35811.1 - 0.08 13.5 0.6 0.31 11.7 0.6 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FeThRed_A PF02941.15 EGC35811.1 - 0.17 12.0 0.0 0.48 10.6 0.0 1.7 1 0 0 1 1 1 0 Ferredoxin thioredoxin reductase variable alpha chain Tmemb_170 PF10190.9 EGC35812.1 - 1.6e-23 83.1 13.0 1.8e-23 82.9 13.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 PRA1 PF03208.19 EGC35812.1 - 8.1 6.1 8.7 11 5.7 8.7 1.1 1 0 0 1 1 1 0 PRA1 family protein zf-C2H2_jaz PF12171.8 EGC35813.1 - 9.8e-11 41.7 17.9 6e-08 32.8 2.2 3.0 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGC35813.1 - 2.3e-08 34.1 6.0 4.6e-08 33.2 0.3 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGC35813.1 - 3.5e-06 27.3 12.9 0.00034 20.9 0.5 3.1 1 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_3rep PF18868.1 EGC35813.1 - 0.0077 16.9 2.5 0.0077 16.9 2.5 2.1 1 1 1 2 2 2 1 Zinc finger C2H2-type, 3 repeats zf-C2H2_4 PF13894.6 EGC35813.1 - 0.014 16.2 0.1 0.014 16.2 0.1 3.2 4 0 0 4 4 3 0 C2H2-type zinc finger C1_4 PF07975.12 EGC35813.1 - 0.031 14.5 4.1 0.79 10.0 0.2 2.8 3 0 0 3 3 3 0 TFIIH C1-like domain DUF2634 PF10934.8 EGC35813.1 - 0.06 13.5 0.1 0.13 12.4 0.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2634) Zf_RING PF16744.5 EGC35813.1 - 0.11 12.6 0.1 0.11 12.6 0.1 2.1 3 0 0 3 3 2 0 KIAA1045 RING finger zf-H2C2_2 PF13465.6 EGC35813.1 - 0.13 12.8 8.1 0.33 11.5 0.5 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-LYAR PF08790.11 EGC35813.1 - 0.19 11.7 5.2 1.1 9.2 1.1 2.6 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger zf-C2H2 PF00096.26 EGC35813.1 - 0.25 11.9 0.4 0.25 11.9 0.4 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type AKAP95 PF04988.12 EGC35813.1 - 0.31 11.3 12.8 1.5 9.0 1.0 2.7 2 2 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-DBF PF07535.12 EGC35813.1 - 0.37 10.9 8.7 0.69 10.1 0.4 2.4 2 0 0 2 2 2 0 DBF zinc finger LIM PF00412.22 EGC35813.1 - 1.4 9.2 6.9 2.8 8.2 0.1 2.9 3 0 0 3 3 3 0 LIM domain Mpp10 PF04006.12 EGC35814.1 - 0.00036 19.1 14.6 0.00061 18.4 14.6 1.3 1 0 0 1 1 1 1 Mpp10 protein SDA1 PF05285.12 EGC35814.1 - 0.0032 17.0 10.3 0.0053 16.2 10.3 1.3 1 0 0 1 1 1 1 SDA1 YL1 PF05764.13 EGC35814.1 - 0.0033 17.6 10.4 0.0059 16.8 10.4 1.4 1 0 0 1 1 1 1 YL1 nuclear protein CDC45 PF02724.14 EGC35814.1 - 0.27 9.5 9.5 0.43 8.8 9.5 1.3 1 0 0 1 1 1 0 CDC45-like protein DNA_pol_phi PF04931.13 EGC35814.1 - 0.48 8.5 22.3 0.037 12.2 16.7 2.1 2 0 0 2 2 2 0 DNA polymerase phi Nop14 PF04147.12 EGC35814.1 - 1.5 6.9 21.7 0.26 9.4 17.7 1.6 2 0 0 2 2 2 0 Nop14-like family Roughex PF06020.11 EGC35814.1 - 1.6 7.8 6.6 3.1 6.8 6.6 1.4 1 0 0 1 1 1 0 Drosophila roughex protein BUD22 PF09073.10 EGC35814.1 - 7.2 5.8 16.4 0.35 10.2 10.8 1.6 2 0 0 2 2 2 0 BUD22 Fumble PF03630.14 EGC35817.1 - 6.4e-132 439.7 0.8 6.4e-132 439.7 0.8 1.7 2 0 0 2 2 2 1 Fumble C2 PF00168.30 EGC35818.1 - 4.3e-23 81.6 0.0 9.1e-23 80.5 0.0 1.5 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.6 EGC35818.1 - 4.3e-19 68.0 16.5 1.5e-08 34.2 0.1 5.1 3 1 2 5 5 5 4 Leucine rich repeat LRR_4 PF12799.7 EGC35818.1 - 4.9e-19 68.1 25.4 7.7e-06 26.2 1.1 6.0 2 1 4 7 7 7 6 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC35818.1 - 4.9e-06 26.1 9.3 0.0091 15.5 0.4 3.6 1 1 2 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.33 EGC35818.1 - 0.0003 20.9 21.0 0.49 11.1 0.2 8.5 8 1 1 9 9 9 2 Leucine Rich Repeat LRR_6 PF13516.6 EGC35818.1 - 5.1 7.4 20.5 2.2 8.5 0.9 6.3 7 0 0 7 7 7 0 Leucine Rich repeat CLTH PF10607.9 EGC35819.1 - 1.8e-35 122.0 5.8 1.8e-35 122.0 5.8 2.0 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain CAMP_factor PF07373.11 EGC35819.1 - 0.0062 16.2 3.5 0.0062 16.2 3.5 2.0 2 0 0 2 2 2 1 CAMP factor (Cfa) U-box PF04564.15 EGC35819.1 - 0.013 15.7 0.6 0.047 13.9 0.0 2.3 3 0 0 3 3 3 0 U-box domain LisH PF08513.11 EGC35819.1 - 0.033 14.2 0.1 0.072 13.1 0.1 1.6 1 0 0 1 1 1 0 LisH G10 PF01125.17 EGC35819.1 - 0.21 11.3 4.5 0.39 10.5 4.0 1.7 1 1 0 1 1 1 0 G10 protein TFIID_NTD2 PF04494.15 EGC35819.1 - 0.22 11.7 10.3 0.29 11.4 0.8 2.8 2 2 1 3 3 3 0 WD40 associated region in TFIID subunit, NTD2 domain DASH_Dad1 PF08649.10 EGC35819.1 - 1.4 9.2 6.1 6 7.1 1.0 3.5 2 1 1 3 3 3 0 DASH complex subunit Dad1 IZUMO PF15005.6 EGC35819.1 - 4.4 7.8 12.6 1.9 9.0 3.8 2.9 2 1 0 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Fzo_mitofusin PF04799.13 EGC35819.1 - 6.6 6.3 13.9 1.7 8.2 0.4 2.8 2 1 1 3 3 3 0 fzo-like conserved region DUF29 PF01724.16 EGC35820.1 - 2.8 8.2 5.7 2 8.6 0.1 3.5 2 1 1 3 3 3 0 Domain of unknown function DUF29 Oxysterol_BP PF01237.18 EGC35821.1 - 8.1e-105 350.7 0.1 1e-104 350.4 0.1 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein LMBR1 PF04791.16 EGC35822.1 - 1.3e-41 143.1 31.8 1.2e-29 103.6 4.3 2.0 1 1 0 2 2 2 2 LMBR1-like membrane protein ATP1G1_PLM_MAT8 PF02038.16 EGC35822.1 - 0.0028 17.0 0.1 0.016 14.6 0.1 2.4 1 0 0 1 1 1 1 ATP1G1/PLM/MAT8 family ASC PF00858.24 EGC35822.1 - 0.55 9.1 2.7 0.46 9.4 0.7 1.9 2 0 0 2 2 2 0 Amiloride-sensitive sodium channel ABC_membrane PF00664.23 EGC35823.1 - 7.6e-69 232.4 40.9 8.7e-35 120.7 22.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC35823.1 - 1.5e-47 161.6 7.0 2.1e-28 99.6 0.1 4.7 4 0 0 4 4 4 3 ABC transporter MMR_HSR1 PF01926.23 EGC35823.1 - 2e-25 89.1 5.0 6.8e-21 74.5 0.0 3.9 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC35823.1 - 1.2e-11 44.8 10.0 0.002 18.1 0.0 4.7 4 0 0 4 4 4 3 RsgA GTPase FeoB_N PF02421.18 EGC35823.1 - 1.4e-10 40.9 0.2 9.1e-10 38.3 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B SMC_N PF02463.19 EGC35823.1 - 2.1e-09 37.1 16.6 0.009 15.5 2.6 5.0 3 2 1 4 4 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC35823.1 - 1.9e-08 33.9 1.7 0.023 14.5 0.2 3.7 3 0 0 3 3 3 3 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGC35823.1 - 5.4e-07 29.8 17.5 0.017 15.2 0.0 5.9 6 2 1 7 7 6 3 Dynamin family AAA_21 PF13304.6 EGC35823.1 - 3.5e-06 27.1 4.4 0.068 13.0 0.6 4.7 3 1 1 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system GTP_EFTU PF00009.27 EGC35823.1 - 4e-06 26.5 1.2 0.01 15.4 0.1 4.0 4 0 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EGC35823.1 - 2.1e-05 24.1 0.7 0.79 9.2 0.1 3.9 4 0 0 4 4 4 2 P-loop containing dynein motor region Roc PF08477.13 EGC35823.1 - 0.00054 20.2 5.9 0.48 10.7 0.0 4.9 5 0 0 5 5 4 1 Ras of Complex, Roc, domain of DAPkinase AAA_18 PF13238.6 EGC35823.1 - 0.0015 19.1 0.5 14 6.3 0.0 4.2 4 0 0 4 4 4 0 AAA domain DUF815 PF05673.13 EGC35823.1 - 0.0018 17.5 3.4 0.16 11.1 0.1 3.8 4 0 0 4 4 4 1 Protein of unknown function (DUF815) cobW PF02492.19 EGC35823.1 - 0.0026 17.4 2.8 1.9 8.1 0.0 3.7 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGC35823.1 - 0.0029 18.0 2.3 3.2 8.1 0.1 3.8 3 1 1 4 4 3 1 AAA ATPase domain TrwB_AAD_bind PF10412.9 EGC35823.1 - 0.0033 16.4 0.3 1.8 7.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA PF00004.29 EGC35823.1 - 0.0033 17.8 0.3 5.4 7.4 0.0 4.1 4 1 0 4 4 3 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGC35823.1 - 0.0037 17.6 0.2 15 6.0 0.0 4.2 3 0 0 3 3 3 0 RNA helicase AAA_22 PF13401.6 EGC35823.1 - 0.0044 17.3 3.9 2.1 8.6 0.2 3.8 3 1 0 3 3 3 1 AAA domain T2SSE PF00437.20 EGC35823.1 - 0.0046 16.1 0.2 0.61 9.1 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein Sigma54_activat PF00158.26 EGC35823.1 - 0.0076 16.0 0.1 0.26 11.0 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.18 EGC35823.1 - 0.008 15.6 3.8 0.93 8.8 0.0 3.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family PduV-EutP PF10662.9 EGC35823.1 - 0.0082 15.9 8.3 2.9 7.6 0.0 4.1 5 0 0 5 5 4 2 Ethanolamine utilisation - propanediol utilisation DEAD PF00270.29 EGC35823.1 - 0.012 15.4 3.0 0.03 14.1 0.6 2.9 3 1 0 3 3 2 0 DEAD/DEAH box helicase IstB_IS21 PF01695.17 EGC35823.1 - 0.07 12.9 4.6 2.4 7.9 0.0 4.5 5 0 0 5 5 5 0 IstB-like ATP binding protein AAA_23 PF13476.6 EGC35823.1 - 0.57 10.6 46.1 2.1 8.8 2.7 5.8 5 0 0 5 5 5 0 AAA domain Aldedh PF00171.22 EGC35824.1 - 5.3e-130 434.0 0.0 6.2e-130 433.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.32 EGC35825.1 - 7.8e-13 48.7 7.8 1.7e-05 25.5 0.2 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF3337 PF11816.8 EGC35825.1 - 4.2e-09 36.5 4.7 3.2e-08 33.6 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3337) WD40_3 PF15911.5 EGC35825.1 - 0.0013 18.7 0.2 0.98 9.5 0.0 2.7 2 0 0 2 2 2 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35825.1 - 0.03 14.6 0.1 0.41 11.0 0.0 3.0 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ribosomal_S8e PF01201.22 EGC35826.1 - 4e-48 163.1 5.1 4e-48 163.1 5.1 1.6 1 1 0 1 1 1 1 Ribosomal protein S8e Pannexin_like PF12534.8 EGC35826.1 - 3.9 6.5 5.8 5.6 6.0 5.8 1.2 1 0 0 1 1 1 0 Pannexin-like TM region of LRRC8 BolA PF01722.18 EGC35827.1 - 8.4e-13 48.4 0.0 9.6e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein FNIP PF05725.12 EGC35829.1 - 2e-05 24.6 33.2 0.0048 17.0 4.7 6.2 5 2 1 6 6 6 3 FNIP Repeat Peptidase_S28 PF05577.12 EGC35830.1 - 6.3e-97 325.1 7.5 7.4e-97 324.9 7.5 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Glyco_transf_20 PF00982.21 EGC35831.1 - 2e-111 373.0 0.0 2.8e-111 372.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGC35831.1 - 5.2e-36 123.9 0.0 7.6e-36 123.4 0.0 1.2 1 0 0 1 1 1 1 Trehalose-phosphatase Homeodomain PF00046.29 EGC35832.1 - 0.00015 21.6 0.1 0.0021 17.9 0.1 2.4 2 0 0 2 2 2 1 Homeodomain Ycf34 PF10718.9 EGC35833.1 - 0.058 14.1 0.8 0.16 12.7 0.1 2.0 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 YccV-like PF08755.11 EGC35833.1 - 0.1 13.1 0.5 0.17 12.4 0.3 1.5 1 1 0 1 1 1 0 Hemimethylated DNA-binding protein YccV like C1_2 PF03107.16 EGC35834.1 - 0.099 13.0 3.5 0.75 10.2 3.5 2.1 1 1 0 1 1 1 0 C1 domain GATA PF00320.27 EGC35835.1 - 2.5e-07 30.2 8.9 1.4e-06 27.8 8.9 2.1 1 1 0 1 1 1 1 GATA zinc finger DUF4508 PF14969.6 EGC35835.1 - 0.044 14.0 0.3 0.06 13.6 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) AT_hook PF02178.19 EGC35835.1 - 0.056 13.3 7.4 0.11 12.4 7.4 1.5 1 0 0 1 1 1 0 AT hook motif RFX5_DNA_bdg PF14621.6 EGC35835.1 - 0.091 12.5 0.4 0.12 12.1 0.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain PHM7_ext PF12621.8 EGC35836.1 - 0.082 13.1 2.6 0.092 12.9 1.4 1.8 1 1 0 1 1 1 0 Extracellular tail, of 10TM putative phosphate transporter DUF3439 PF11921.8 EGC35836.1 - 1.4 8.9 6.6 0.18 11.7 2.2 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) HMG_box PF00505.19 EGC35839.1 - 1.7e-18 66.8 3.7 3.5e-18 65.8 3.7 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC35839.1 - 4.3e-14 52.9 4.2 7.2e-14 52.1 3.5 1.8 1 1 0 1 1 1 1 HMG-box domain tRNA-synt_2c PF01411.19 EGC35840.1 - 7.7e-71 239.3 1.3 2.5e-62 211.2 0.4 2.0 1 1 1 2 2 2 2 tRNA synthetases class II (A) ArfGap PF01412.18 EGC35842.1 - 0.026 14.6 0.6 0.04 14.0 0.6 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf GATA PF00320.27 EGC35842.1 - 0.17 11.5 4.7 0.39 10.4 4.7 1.6 1 0 0 1 1 1 0 GATA zinc finger LAGLIDADG_1 PF00961.19 EGC35843.1 - 0.038 14.9 4.2 0.06 14.3 4.2 1.4 1 1 0 1 1 1 0 LAGLIDADG endonuclease DUF4264 PF14084.6 EGC35844.1 - 0.047 13.3 0.0 0.36 10.5 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) FNIP PF05725.12 EGC35845.1 - 2e-35 120.7 60.3 5.6e-11 42.4 2.8 9.9 7 2 5 12 12 12 8 FNIP Repeat Pkinase PF00069.25 EGC35846.1 - 7.7e-19 68.1 0.0 1.6e-16 60.5 0.0 2.6 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35846.1 - 9.3e-19 67.7 0.0 3.2e-15 56.1 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGC35846.1 - 0.00048 20.1 0.0 0.00061 19.8 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGC35846.1 - 0.0019 17.5 0.0 0.0027 17.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase FOXP-CC PF16159.5 EGC35847.1 - 0.026 15.2 0.2 0.13 12.9 0.1 2.2 2 0 0 2 2 2 0 FOXP coiled-coil domain DUF5051 PF16473.5 EGC35847.1 - 0.035 14.1 0.0 0.61 10.1 0.0 2.4 2 1 0 2 2 2 0 3' exoribonuclease, RNase T-like Vta1 PF04652.16 EGC35850.1 - 0.031 14.3 0.2 0.2 11.6 0.0 2.1 2 0 0 2 2 2 0 Vta1 like PRP38 PF03371.15 EGC35850.1 - 0.091 12.6 2.3 2.2 8.1 0.4 2.3 2 0 0 2 2 2 0 PRP38 family FOXP-CC PF16159.5 EGC35850.1 - 0.14 12.8 0.2 0.37 11.4 0.2 1.8 1 1 0 1 1 1 0 FOXP coiled-coil domain RNase_T PF00929.24 EGC35851.1 - 1.6e-13 51.5 0.1 1.3e-11 45.3 0.0 2.6 2 0 0 2 2 2 1 Exonuclease CENP-F_leu_zip PF10473.9 EGC35851.1 - 0.0016 18.5 17.0 0.0034 17.4 17.0 1.5 1 0 0 1 1 1 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF5051 PF16473.5 EGC35851.1 - 0.002 18.2 0.2 0.0082 16.1 0.0 2.2 2 1 0 2 2 2 1 3' exoribonuclease, RNase T-like DUF3450 PF11932.8 EGC35851.1 - 0.069 12.4 15.2 0.13 11.6 14.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) Fungal_TACC PF12709.7 EGC35851.1 - 0.32 11.5 16.9 1.9 9.0 6.8 3.3 1 1 1 2 2 2 0 Fungal Transforming acidic coiled-coil (TACC) proteins Exonuc_VII_L PF02601.15 EGC35851.1 - 0.39 10.2 11.6 0.7 9.4 11.6 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF2630 PF10944.8 EGC35851.1 - 0.61 10.6 7.7 0.31 11.5 4.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) Mur_ligase_M PF08245.12 EGC35851.1 - 0.71 9.8 6.0 2.6 8.0 4.9 2.3 1 1 0 2 2 2 0 Mur ligase middle domain zf-C4H2 PF10146.9 EGC35851.1 - 0.98 9.7 14.6 0.23 11.7 9.7 2.1 2 0 0 2 2 2 0 Zinc finger-containing protein PRKG1_interact PF15898.5 EGC35851.1 - 1.1 10.3 17.7 2.3 9.1 2.1 3.1 3 0 0 3 3 3 0 cGMP-dependent protein kinase interacting domain THOC7 PF05615.13 EGC35851.1 - 2.8 8.3 17.0 1.5 9.1 11.7 2.5 1 1 1 2 2 2 0 Tho complex subunit 7 APG6_N PF17675.1 EGC35851.1 - 5.1 7.6 23.7 1.1 9.7 19.4 2.1 2 0 0 2 2 2 0 Apg6 coiled-coil region Myc-LZ PF02344.15 EGC35851.1 - 8.1 6.6 9.1 18 5.6 3.9 2.7 2 0 0 2 2 2 0 Myc leucine zipper domain GATA PF00320.27 EGC35853.1 - 0.00045 19.8 8.4 0.00071 19.1 8.4 1.3 1 0 0 1 1 1 1 GATA zinc finger zf_UBZ PF18439.1 EGC35853.1 - 1.2 8.8 3.5 0.72 9.5 0.4 2.0 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger Eapp_C PF10238.9 EGC35854.1 - 8.5e-41 139.5 17.5 2.2e-38 131.6 17.5 2.0 1 1 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.14 EGC35854.1 - 0.029 14.6 7.5 0.043 14.0 7.5 1.3 1 0 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly PBP1_TM PF14812.6 EGC35854.1 - 0.16 12.4 1.9 8.7 6.8 0.9 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EGC35854.1 - 5.8 7.2 9.2 1.3 9.3 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) CAP PF00188.26 EGC35855.1 - 5.1e-13 50.0 1.4 6.5e-13 49.6 0.1 1.8 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Trypan_PARP PF05887.11 EGC35855.1 - 9.8 6.2 17.0 18 5.3 17.0 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase PF00069.25 EGC35856.1 - 0.0044 16.4 1.7 0.006 16.0 1.7 1.2 1 0 0 1 1 1 1 Protein kinase domain DUF244 PF03112.14 EGC35856.1 - 0.015 15.1 4.3 0.018 14.9 3.4 1.6 1 1 1 2 2 2 0 Uncharacterized protein family (ORF7) DUF Pkinase PF00069.25 EGC35857.1 - 4.6e-05 22.9 0.0 6.2e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FNIP PF05725.12 EGC35857.1 - 0.013 15.7 0.2 0.013 15.7 0.2 4.0 3 1 1 4 4 4 0 FNIP Repeat E1-E2_ATPase PF00122.20 EGC35859.1 - 4.6e-45 153.4 1.7 4.6e-45 153.4 1.7 2.3 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.21 EGC35859.1 - 2e-39 135.2 3.1 2e-39 135.2 3.1 2.0 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Cation_ATPase PF13246.6 EGC35859.1 - 1.9e-24 85.5 0.0 4.1e-24 84.5 0.0 1.6 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC35859.1 - 2e-22 80.5 0.0 6.6e-20 72.3 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC35859.1 - 2.1e-14 53.0 0.0 4.3e-14 52.0 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGC35859.1 - 0.0014 18.4 0.3 0.0045 16.8 0.2 4.7 5 0 0 5 5 5 2 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC35859.1 - 0.012 16.0 0.0 0.073 13.5 0.0 2.1 1 1 0 1 1 1 0 haloacid dehalogenase-like hydrolase Ac76 PF05814.11 EGC35859.1 - 0.1 12.6 0.3 2.4 8.2 0.1 2.9 2 0 0 2 2 2 0 Orf76 (Ac76) DUF5513 PF17632.2 EGC35859.1 - 0.13 12.6 0.2 9.7 6.7 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5513) ChAPs PF09295.10 EGC35860.1 - 1.2e-21 77.2 0.0 3.2e-16 59.3 0.0 3.0 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.6 EGC35860.1 - 1.6e-06 28.4 1.5 0.11 13.4 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC35860.1 - 4.1e-06 26.5 2.2 0.23 11.6 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC35860.1 - 0.00026 21.6 0.0 0.34 11.6 0.0 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC35860.1 - 0.00042 20.8 0.0 0.47 11.0 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC35860.1 - 0.0053 16.9 1.4 5.1 7.6 0.0 4.6 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC35860.1 - 0.016 15.1 1.9 1.1 9.3 0.7 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC35860.1 - 0.019 15.3 0.1 3.7 7.9 0.0 2.9 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC35860.1 - 0.056 13.3 0.9 30 4.6 0.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC35860.1 - 0.084 13.5 2.2 1.3 9.8 0.1 3.2 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC35860.1 - 0.13 12.7 0.4 6.2 7.4 0.1 3.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGC35860.1 - 0.14 12.9 0.0 16 6.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC35860.1 - 0.16 12.1 0.1 4.7 7.5 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGC35860.1 - 0.16 12.1 0.7 4 7.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Peptidase_M48_N PF16491.5 EGC35861.1 - 5.2e-15 55.8 17.9 5.2e-15 55.8 17.9 1.9 2 0 0 2 2 2 1 CAAX prenyl protease N-terminal, five membrane helices Peptidase_M48 PF01435.18 EGC35861.1 - 1.2e-13 51.3 0.0 2.2e-13 50.4 0.0 1.4 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.11 EGC35861.1 - 9.5e-05 21.7 1.9 0.00021 20.6 1.3 1.9 1 1 1 2 2 2 1 BlaR1 peptidase M56 DUF2268 PF10026.9 EGC35861.1 - 0.0095 15.5 0.2 0.015 14.9 0.2 1.2 1 0 0 1 1 1 1 Predicted Zn-dependent protease (DUF2268) DUF3920 PF13058.6 EGC35861.1 - 0.015 15.5 0.2 0.053 13.7 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3920) DUF4157 PF13699.6 EGC35861.1 - 0.24 11.7 0.0 0.42 10.9 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4157) Mon1 PF03164.14 EGC35862.1 - 1.2e-12 47.7 3.6 1.2e-12 47.7 3.6 2.2 2 0 0 2 2 2 1 Trafficking protein Mon1 PG_binding_1 PF01471.18 EGC35862.1 - 1.9e-07 31.2 0.0 3.6e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain FAM60A PF15396.6 EGC35862.1 - 0.69 9.9 14.3 2.2 8.2 0.0 3.3 3 0 0 3 3 3 0 Protein Family FAM60A Ras PF00071.22 EGC35863.1 - 4.8e-61 205.1 0.2 5.6e-61 204.9 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35863.1 - 5.3e-34 117.0 0.0 7.5e-34 116.5 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35863.1 - 8.2e-15 54.7 0.0 1e-14 54.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGC35863.1 - 3.5e-05 23.8 1.5 0.1 12.5 0.1 2.6 1 1 1 3 3 3 2 RsgA GTPase Gtr1_RagA PF04670.12 EGC35863.1 - 0.0002 20.8 0.1 0.00023 20.6 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC35863.1 - 0.0011 19.0 0.0 0.0016 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC35863.1 - 0.005 16.4 0.2 0.024 14.2 0.0 2.0 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGC35863.1 - 0.0088 15.9 0.1 0.083 12.6 0.0 1.9 1 1 0 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.18 EGC35863.1 - 0.011 15.3 0.0 0.052 13.1 0.0 1.9 1 1 0 1 1 1 0 Ferrous iron transport protein B SRPRB PF09439.10 EGC35863.1 - 0.014 14.8 0.1 0.019 14.4 0.1 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGC35863.1 - 0.03 13.9 0.0 0.17 11.4 0.0 1.9 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EGC35863.1 - 0.032 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 EGC35863.1 - 0.045 14.1 0.0 0.061 13.7 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain Septin PF00735.18 EGC35863.1 - 0.08 12.2 0.4 0.25 10.6 0.0 1.8 2 0 0 2 2 2 0 Septin PIN_9 PF18477.1 EGC35863.1 - 0.081 13.2 0.0 0.12 12.6 0.0 1.2 1 0 0 1 1 1 0 PIN like domain AAA_22 PF13401.6 EGC35863.1 - 0.083 13.2 0.0 0.2 11.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGC35863.1 - 0.13 12.1 0.0 0.3 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain PIP5K PF01504.18 EGC35864.1 - 2.3e-69 233.7 8.5 2.3e-69 233.7 8.5 2.5 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Adeno_PV PF03910.13 EGC35864.1 - 5.3 5.6 5.6 2.6 6.7 2.7 1.8 2 0 0 2 2 2 0 Adenovirus minor core protein PV WD40 PF00400.32 EGC35865.1 - 4.9e-44 147.4 26.9 2.9e-08 34.2 0.1 7.8 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.7 EGC35865.1 - 1.5e-11 44.0 0.9 2.7e-11 43.2 0.9 1.5 1 0 0 1 1 1 1 F-box-like ANAPC4_WD40 PF12894.7 EGC35865.1 - 2.4e-10 40.6 5.5 0.016 15.5 0.1 5.5 2 1 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC35865.1 - 3.8e-09 36.3 2.2 0.00029 20.3 0.1 2.7 1 1 1 2 2 2 2 WD40-like domain F-box PF00646.33 EGC35865.1 - 1.6e-06 27.8 2.5 4.6e-06 26.4 2.5 1.8 1 1 0 1 1 1 1 F-box domain PIN_2 PF10130.9 EGC35865.1 - 0.047 13.9 1.2 0.1 12.8 1.2 1.5 1 0 0 1 1 1 0 PIN domain YgaB PF14182.6 EGC35865.1 - 1.3 9.5 6.9 3.9 8.0 6.9 1.9 1 1 0 1 1 1 0 YgaB-like protein COMM_domain PF07258.14 EGC35866.1 - 4e-14 52.5 0.2 4.3e-14 52.4 0.2 1.0 1 0 0 1 1 1 1 COMM domain Nop52 PF05997.12 EGC35867.1 - 2.2e-56 191.1 5.3 3.6e-56 190.4 5.3 1.4 1 0 0 1 1 1 1 Nucleolar protein,Nop52 BUD22 PF09073.10 EGC35867.1 - 0.0013 18.1 25.6 0.0013 18.1 25.6 1.5 2 0 0 2 2 2 1 BUD22 YL1 PF05764.13 EGC35867.1 - 0.011 15.9 37.7 0.018 15.2 37.7 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PRESAN PF09687.10 EGC35867.1 - 0.025 15.1 0.8 0.025 15.1 0.8 2.8 3 0 0 3 3 3 0 Plasmodium RESA N-terminal RRN3 PF05327.11 EGC35867.1 - 0.087 11.4 0.1 0.087 11.4 0.1 3.0 2 1 0 2 2 2 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.12 EGC35867.1 - 0.44 8.7 34.1 0.65 8.1 34.1 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.12 EGC35867.1 - 2.8 7.3 37.1 4.3 6.7 37.1 1.2 1 0 0 1 1 1 0 SDA1 TIG PF01833.24 EGC35868.1 - 0.00011 22.1 0.9 0.00011 22.1 0.9 4.9 4 0 0 4 4 4 2 IPT/TIG domain CrgA PF06781.12 EGC35868.1 - 0.078 13.0 0.1 0.17 12.0 0.1 1.5 1 0 0 1 1 1 0 Cell division protein CrgA PMP1_2 PF08114.11 EGC35868.1 - 0.26 11.1 1.5 0.57 10.0 1.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family NUDIX PF00293.28 EGC35869.1 - 0.08 13.0 0.3 1.2 9.2 0.3 2.1 1 1 0 1 1 1 0 NUDIX domain Exonuc_VII_S PF02609.16 EGC35869.1 - 0.095 12.8 0.2 0.18 11.9 0.2 1.4 1 0 0 1 1 1 0 Exonuclease VII small subunit PTPS PF01242.19 EGC35870.1 - 8.4e-34 116.2 0.2 9.4e-34 116.0 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase WCCH PF03716.14 EGC35871.1 - 0.18 11.5 0.0 0.27 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif ESCRT-II PF05871.12 EGC35872.1 - 9.8e-49 165.2 2.5 1.2e-48 164.9 2.5 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Pkinase PF00069.25 EGC35873.1 - 2e-36 125.7 0.0 4.7e-36 124.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35873.1 - 2.7e-23 82.6 0.0 5.3e-23 81.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.12 EGC35873.1 - 3e-14 52.9 17.0 2.8e-07 30.6 0.0 6.3 5 1 2 7 7 7 2 FNIP Repeat Kinase-like PF14531.6 EGC35873.1 - 1.3e-05 24.7 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.20 EGC35873.1 - 0.017 14.7 0.4 0.15 11.6 0.2 2.1 1 1 1 2 2 2 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.9 EGC35873.1 - 0.027 14.0 0.0 0.052 13.1 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL APH PF01636.23 EGC35873.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC35873.1 - 0.033 13.0 0.0 0.059 12.1 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase Kdo PF06293.14 EGC35873.1 - 0.046 13.1 0.0 0.076 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.22 EGC35873.1 - 0.058 13.0 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 RIO1 family Ras PF00071.22 EGC35874.1 - 1.8e-42 144.7 0.2 2.2e-42 144.4 0.2 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35874.1 - 2.8e-26 92.1 0.3 5e-26 91.3 0.1 1.5 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35874.1 - 7.8e-13 48.2 0.1 9.2e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC35874.1 - 6.8e-07 28.9 0.0 8.8e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC35874.1 - 0.055 13.4 0.0 0.57 10.1 0.0 2.3 2 1 1 3 3 3 0 RsgA GTPase zf-CDGSH PF09360.10 EGC35875.1 - 1.9e-22 79.2 7.8 8.8e-11 41.9 0.6 2.5 2 1 0 2 2 2 2 Iron-binding zinc finger CDGSH type MSL2-CXC PF16682.5 EGC35875.1 - 0.02 15.0 3.6 0.35 11.0 0.3 2.3 2 0 0 2 2 2 0 CXC domain of E3 ubiquitin-protein ligase MSL2 DUF3844 PF12955.7 EGC35875.1 - 1.4 9.0 4.3 8.9 6.5 0.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3844) RRM_1 PF00076.22 EGC35876.1 - 3.1e-33 113.4 0.4 8.8e-18 63.9 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC35876.1 - 0.0024 17.4 0.0 0.65 9.6 0.1 2.2 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC35876.1 - 0.0027 17.8 0.0 0.012 15.8 0.0 2.0 1 1 1 2 2 2 1 RNA recognition motif HAGH_C PF16123.5 EGC35877.1 - 5.2e-26 91.0 0.2 8.2e-26 90.3 0.2 1.3 1 0 0 1 1 1 1 Hydroxyacylglutathione hydrolase C-terminus Lactamase_B PF00753.27 EGC35877.1 - 3.1e-13 50.2 2.2 1.1e-12 48.4 2.2 1.9 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC35877.1 - 0.00013 21.5 0.1 0.0011 18.5 0.1 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_41 PF13844.6 EGC35878.1 - 6e-37 127.2 0.0 5.8e-21 74.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_20 PF14561.6 EGC35878.1 - 5.5e-08 33.0 1.8 0.0013 19.0 0.3 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC35878.1 - 1.2e-06 28.9 2.1 9.7e-05 22.8 0.6 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC35878.1 - 4.4e-06 27.2 0.0 1.4e-05 25.7 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC35878.1 - 6.8e-06 26.1 4.7 0.099 13.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC35878.1 - 0.00083 20.0 0.0 0.012 16.4 0.0 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC35878.1 - 0.0073 16.3 6.7 0.041 14.0 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC35878.1 - 0.023 14.5 6.4 0.43 10.5 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC35878.1 - 0.097 12.9 7.0 1.6 9.1 0.0 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC35878.1 - 0.11 13.1 0.0 21 6.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC35878.1 - 0.27 11.5 4.1 0.95 9.8 0.1 3.1 2 2 1 3 3 3 0 Tetratricopeptide repeat Adenylsucc_synt PF00709.21 EGC35879.1 - 8.4e-182 604.7 0.0 9.6e-182 604.6 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase Alpha-amylase PF00128.24 EGC35880.1 - 1.8e-19 70.5 0.0 4.9e-19 69.1 0.0 1.7 1 1 0 1 1 1 1 Alpha amylase, catalytic domain LBP_C PF17386.2 EGC35880.1 - 0.014 15.2 0.7 0.069 13.0 0.0 2.4 3 0 0 3 3 3 0 Lacto-N-biose phosphorylase C-terminal domain Malt_amylase_C PF16657.5 EGC35880.1 - 0.046 13.8 0.1 0.13 12.4 0.0 1.9 2 0 0 2 2 2 0 Maltogenic Amylase, C-terminal domain hDGE_amylase PF14701.6 EGC35880.1 - 0.088 11.9 0.0 0.16 11.0 0.0 1.3 1 0 0 1 1 1 0 Glycogen debranching enzyme, glucanotransferase domain DUF1635 PF07795.11 EGC35881.1 - 0.1 12.5 7.0 0.11 12.3 7.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) LMP PF04778.12 EGC35881.1 - 0.1 12.5 12.3 0.21 11.5 12.1 1.7 1 1 0 1 1 1 0 LMP repeated region Golgin_A5 PF09787.9 EGC35881.1 - 0.11 11.9 14.5 0.16 11.4 14.2 1.4 1 1 0 1 1 1 0 Golgin subfamily A member 5 OEP PF02321.18 EGC35881.1 - 0.16 11.8 14.0 0.68 9.7 10.0 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein TolA_bind_tri PF16331.5 EGC35881.1 - 0.26 11.4 10.8 0.034 14.2 5.1 2.4 2 1 0 2 2 2 0 TolA binding protein trimerisation Exonuc_VII_L PF02601.15 EGC35881.1 - 0.42 10.1 8.4 0.52 9.8 8.4 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit Jnk-SapK_ap_N PF09744.9 EGC35881.1 - 0.72 10.1 14.6 1.3 9.3 14.1 1.6 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 Fib_alpha PF08702.10 EGC35881.1 - 3.7 7.7 15.1 5.7 7.1 11.9 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Sugarporin_N PF11471.8 EGC35881.1 - 8.1 6.5 13.9 2.8 8.0 3.8 2.8 2 1 1 3 3 3 0 Maltoporin periplasmic N-terminal extension CactinC_cactus PF09732.9 EGC35882.1 - 1.6e-59 199.3 9.7 3.3e-59 198.3 9.7 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.9 EGC35882.1 - 9e-46 156.1 1.3 9e-46 156.1 1.3 2.7 2 1 1 3 3 3 1 Conserved mid region of cactin F_actin_bund_C PF18060.1 EGC35883.1 - 5.1e-25 87.4 0.7 1.1e-24 86.4 0.7 1.6 1 0 0 1 1 1 1 F actin bundling C terminal EF-hand_5 PF13202.6 EGC35883.1 - 0.099 12.2 0.0 0.31 10.6 0.0 1.9 1 0 0 1 1 1 0 EF hand Dockerin_1 PF00404.18 EGC35883.1 - 0.16 12.2 0.0 0.47 10.7 0.0 1.8 1 0 0 1 1 1 0 Dockerin type I domain ABC_tran_CTD PF16326.5 EGC35883.1 - 0.48 10.7 4.0 0.45 10.8 1.4 2.2 2 0 0 2 2 2 0 ABC transporter C-terminal domain HR1 PF02185.16 EGC35883.1 - 8.4 6.6 7.2 59 3.9 3.0 2.9 2 1 0 2 2 2 0 Hr1 repeat DUF2804 PF10974.8 EGC35884.1 - 2.6e-118 395.3 3.6 3.2e-118 395.0 3.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) RP-C_C PF11800.8 EGC35884.1 - 0.98 9.5 4.0 1.3 9.0 4.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CDC45 PF02724.14 EGC35886.1 - 0.0037 15.6 16.9 0.0073 14.7 16.9 1.4 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.12 EGC35886.1 - 0.0057 16.1 33.1 0.016 14.7 33.1 1.7 1 0 0 1 1 1 1 SDA1 Nop14 PF04147.12 EGC35886.1 - 1.5 7.0 36.3 2.8 6.1 36.3 1.3 1 0 0 1 1 1 0 Nop14-like family Toxin_29 PF08116.11 EGC35886.1 - 1.5 8.9 5.2 4.4 7.4 0.8 2.7 2 0 0 2 2 2 0 PhTx neurotoxin family Tim54 PF11711.8 EGC35886.1 - 3.3 6.4 11.2 6.5 5.4 11.2 1.5 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 RP-C_C PF11800.8 EGC35886.1 - 4.4 7.3 5.9 9.3 6.3 5.9 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region Presenilin PF01080.17 EGC35886.1 - 9.9 4.8 14.4 19 3.9 14.4 1.4 1 0 0 1 1 1 0 Presenilin HD_3 PF13023.6 EGC35887.1 - 5.3e-48 163.1 0.9 6.7e-48 162.7 0.9 1.1 1 0 0 1 1 1 1 HD domain HD_2 PF12917.7 EGC35887.1 - 3.1e-16 59.7 0.6 3.8e-16 59.4 0.6 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme HD PF01966.22 EGC35887.1 - 8.6e-07 29.2 0.1 2e-06 28.0 0.1 1.6 1 1 0 1 1 1 1 HD domain HDOD PF08668.12 EGC35887.1 - 0.081 12.4 0.0 0.12 11.8 0.0 1.2 1 0 0 1 1 1 0 HDOD domain FNIP PF05725.12 EGC35888.1 - 6.7e-288 928.8 144.6 5.8e-15 55.2 0.0 18.3 6 3 17 25 25 25 25 FNIP Repeat Phage_min_tail PF05939.13 EGC35888.1 - 7.6e-15 55.2 11.1 17 5.9 0.0 15.5 7 6 9 17 17 17 3 Phage minor tail protein Keratin_assoc PF09775.9 EGC35888.1 - 0.077 12.7 0.8 28 4.4 0.0 5.5 5 3 2 7 7 7 0 Keratinocyte-associated protein 2 Xol-1_GHMP-like PF09109.10 EGC35888.1 - 0.18 11.7 0.4 55 3.6 0.0 5.1 4 2 2 6 6 6 0 Switch protein XOL-1, GHMP-like HTH_ABP1_N PF18107.1 EGC35888.1 - 0.2 11.4 0.2 1.1e+02 2.7 0.0 5.7 7 0 0 7 7 7 0 Fission yeast centromere protein N-terminal domain DUF3215 PF11503.8 EGC35888.1 - 1.4 8.8 8.5 1.4e+02 2.5 0.0 6.9 7 2 2 9 9 9 0 Protein of unknown function (DUF3215) FNIP PF05725.12 EGC35889.1 - 8.1e-69 227.6 23.5 1.9e-15 56.7 0.8 6.3 4 1 1 6 6 6 6 FNIP Repeat DUF3215 PF11503.8 EGC35889.1 - 0.27 11.1 4.7 16 5.5 0.0 4.7 6 0 0 6 6 6 0 Protein of unknown function (DUF3215) EGF_2 PF07974.13 EGC35890.1 - 0.00035 20.9 39.8 0.0045 17.3 11.3 3.6 3 0 0 3 3 3 2 EGF-like domain TIG PF01833.24 EGC35890.1 - 0.00049 20.1 2.0 0.00049 20.1 2.0 3.2 3 1 0 3 3 3 1 IPT/TIG domain PMP1_2 PF08114.11 EGC35890.1 - 0.0057 16.4 2.0 0.015 15.0 2.0 1.6 1 0 0 1 1 1 1 ATPase proteolipid family Laminin_EGF PF00053.24 EGC35890.1 - 0.073 13.2 28.0 0.094 12.9 6.2 3.9 2 1 1 3 3 3 0 Laminin EGF domain EGF_2 PF07974.13 EGC35891.1 - 0.00035 20.9 48.6 0.0018 18.6 18.3 3.2 3 0 0 3 3 3 2 EGF-like domain TIG PF01833.24 EGC35891.1 - 0.0015 18.6 1.5 0.0015 18.6 1.5 3.4 3 1 0 3 3 3 1 IPT/TIG domain EGF_Tenascin PF18720.1 EGC35891.1 - 0.093 12.8 20.0 0.15 12.1 2.8 3.5 3 0 0 3 3 3 0 Tenascin EGF domain Laminin_EGF PF00053.24 EGC35891.1 - 0.84 9.8 32.2 1.2 9.3 14.5 3.1 2 1 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 EGC35891.1 - 1.3 9.8 24.7 2.4 8.9 10.1 3.4 2 0 0 2 2 2 0 Human growth factor-like EGF DUF3430 PF11912.8 EGC35892.1 - 1.5e-24 87.2 39.9 1.9e-24 86.9 39.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) O_anti_polymase PF01901.16 EGC35892.1 - 0.074 12.3 0.5 0.12 11.6 0.5 1.4 1 1 0 1 1 1 0 Putative O-antigen polymerase WD40 PF00400.32 EGC35893.1 - 3.3e-48 160.6 19.3 2.3e-08 34.6 0.5 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC35893.1 - 2.1e-18 66.4 6.3 0.0029 17.9 0.1 7.6 2 1 6 8 8 8 6 Anaphase-promoting complex subunit 4 WD40 domain Ge1_WD40 PF16529.5 EGC35893.1 - 9.6e-06 24.8 0.3 0.052 12.5 0.0 4.2 2 2 2 5 5 5 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC35893.1 - 8.2e-05 21.4 3.7 2 7.0 0.0 4.9 1 1 2 4 4 4 3 Nucleoporin Nup120/160 LisH_TPL PF17814.1 EGC35893.1 - 0.011 15.4 0.0 0.033 13.9 0.0 1.9 1 0 0 1 1 1 0 LisH-like dimerisation domain Erf4 PF10256.9 EGC35894.1 - 7e-27 93.8 0.5 7.7e-27 93.7 0.5 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ADH_N PF08240.12 EGC35895.1 - 1.5e-21 76.3 3.9 2.6e-21 75.5 3.9 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.26 EGC35895.1 - 1e-15 57.9 0.0 1.9e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.19 EGC35895.1 - 0.0029 17.0 0.0 0.0051 16.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.6 EGC35895.1 - 0.018 16.1 0.0 0.027 15.5 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.21 EGC35895.1 - 0.031 13.6 0.0 0.047 13.0 0.0 1.2 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain ELFV_dehydrog PF00208.21 EGC35895.1 - 0.14 11.9 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Elf1 PF05129.13 EGC35895.1 - 0.91 9.6 6.0 5.4 7.1 0.2 3.1 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like Tnp_22_dsRBD PF17490.2 EGC35896.1 - 0.049 13.6 1.2 26 4.9 0.2 3.5 1 1 3 4 4 4 0 L1 transposable element dsRBD-like domain Adeno_E3 PF06040.11 EGC35896.1 - 0.18 12.0 3.3 0.24 11.6 2.9 1.4 1 1 1 2 2 2 0 Adenovirus E3 protein TIG PF01833.24 EGC35897.1 - 2.3e-06 27.6 0.8 2.3e-06 27.6 0.8 3.4 2 1 0 2 2 2 1 IPT/TIG domain EGF_2 PF07974.13 EGC35897.1 - 0.0029 17.9 13.1 0.009 16.4 13.1 1.9 1 0 0 1 1 1 1 EGF-like domain LRR_4 PF12799.7 EGC35897.1 - 0.58 10.7 7.5 9 6.9 0.2 4.0 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) EGF PF00008.27 EGC35897.1 - 0.97 9.8 7.7 2.7 8.4 7.7 1.8 1 0 0 1 1 1 0 EGF-like domain RmlD_sub_bind PF04321.17 EGC35898.1 - 3.3e-49 167.5 0.0 4.7e-49 167.0 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGC35898.1 - 9.6e-21 74.3 0.0 1.6e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC35898.1 - 9.5e-11 41.7 0.1 2.4e-10 40.3 0.1 1.6 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC35898.1 - 1.2e-08 34.4 0.0 6e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein SDA1 PF05285.12 EGC35898.1 - 2.4 7.5 25.4 3.4 7.0 25.4 1.3 1 0 0 1 1 1 0 SDA1 Pkinase_Tyr PF07714.17 EGC35899.1 - 4.2e-38 131.1 0.0 6.8e-38 130.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35899.1 - 3.2e-33 115.2 0.0 6.8e-33 114.1 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 EGC35899.1 - 2.7e-05 24.1 0.8 9.6 6.4 0.0 5.5 5 0 0 5 5 5 1 Armadillo/beta-catenin-like repeat Rcd1 PF04078.13 EGC35899.1 - 0.013 14.8 4.3 0.53 9.5 0.0 3.2 3 1 1 4 4 4 0 Cell differentiation family, Rcd1-like Kinase-like PF14531.6 EGC35899.1 - 0.033 13.5 0.0 0.06 12.7 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGC35899.1 - 0.068 12.5 0.1 0.14 11.5 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Peptidase_M24 PF00557.24 EGC35900.1 - 1.9e-51 174.7 0.1 2.7e-51 174.3 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 dCache_3 PF14827.6 EGC35900.1 - 0.012 15.3 0.1 0.017 14.8 0.1 1.2 1 0 0 1 1 1 0 Double sensory domain of two-component sensor kinase DUF3685 PF12452.8 EGC35900.1 - 0.68 9.6 5.9 1 9.1 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) ADH_N_2 PF16884.5 EGC35901.1 - 1.3e-23 83.0 0.0 2.1e-23 82.3 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGC35901.1 - 1.2e-19 70.6 0.0 2.4e-19 69.6 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC35901.1 - 5.2e-07 30.8 0.0 9.9e-07 29.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.16 EGC35901.1 - 0.072 13.7 0.0 0.52 11.0 0.0 2.2 2 0 0 2 2 2 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II OTU PF02338.19 EGC35902.1 - 2.1e-10 41.2 0.1 4e-10 40.3 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 EGC35902.1 - 1 9.3 34.5 1.8 8.4 34.5 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MSP1a PF11670.8 EGC35902.1 - 2.7 7.2 0.0 2.7 7.2 0.0 2.9 2 1 1 3 3 3 0 Major surface protein 1a (MSP1a) Phage_sheath_1N PF17481.2 EGC35904.1 - 0.15 12.6 2.7 0.41 11.2 2.7 1.8 1 0 0 1 1 1 0 Phage tail sheath protein beta-sandwich domain NHL PF01436.21 EGC35904.1 - 0.16 12.1 0.1 0.4 10.8 0.1 1.7 1 0 0 1 1 1 0 NHL repeat Dicty_spore_N PF04562.12 EGC35905.1 - 3.4e-19 69.6 10.9 3.4e-19 69.6 10.9 4.3 2 1 0 3 3 3 1 Dictyostelium spore coat protein, N terminus Apolipoprotein PF01442.18 EGC35906.1 - 7.2e-09 35.8 49.4 7.5e-06 25.9 18.8 2.4 1 1 2 3 3 3 3 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EGC35906.1 - 4.9e-07 30.2 50.4 0.0041 17.6 10.7 5.3 2 1 2 4 4 4 3 YtxH-like protein DUF883 PF05957.13 EGC35906.1 - 6e-07 30.0 39.6 0.016 15.8 10.9 4.5 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) AT_hook PF02178.19 EGC35906.1 - 0.031 14.1 4.3 0.089 12.7 4.3 1.8 1 0 0 1 1 1 0 AT hook motif ApoLp-III PF07464.11 EGC35906.1 - 0.041 14.0 41.0 56 3.8 11.4 3.7 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Synuclein PF01387.17 EGC35906.1 - 0.17 12.1 36.0 0.12 12.6 3.8 4.2 1 1 3 4 4 4 0 Synuclein Zot PF05707.12 EGC35906.1 - 0.33 10.6 6.8 0.22 11.1 0.5 2.5 1 1 0 2 2 2 0 Zonular occludens toxin (Zot) DBD_Tnp_Hermes PF10683.9 EGC35906.1 - 0.56 9.9 8.0 1.5 8.5 1.3 2.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain E6 PF00518.17 EGC35906.1 - 0.98 9.9 8.6 1.8 9.0 1.9 2.5 1 1 1 2 2 2 0 Early Protein (E6) Prominin PF05478.11 EGC35906.1 - 3.8 5.3 24.1 2.7 5.8 6.0 2.5 1 1 1 2 2 2 0 Prominin Prenyltransf PF01255.19 EGC35906.1 - 4 6.9 17.2 13 5.2 15.6 2.5 1 1 0 1 1 1 0 Putative undecaprenyl diphosphate synthase DUF4851 PF16143.5 EGC35906.1 - 4 6.8 6.9 0.68 9.4 0.3 2.8 2 2 1 4 4 4 0 Domain of unknown function (DUF4851) DUF885 PF05960.11 EGC35906.1 - 5.6 6.5 26.2 10 5.6 26.2 1.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF885) ApoO PF09769.9 EGC35906.1 - 6.9 6.6 18.9 29 4.6 2.4 4.7 1 1 3 4 4 4 0 Apolipoprotein O PhaP_Bmeg PF09602.10 EGC35906.1 - 9.8 6.1 25.4 1.7 8.6 9.4 3.3 1 1 3 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) LEA_4 PF02987.16 EGC35907.1 - 0.022 14.8 0.1 0.022 14.8 0.1 2.6 4 0 0 4 4 4 0 Late embryogenesis abundant protein GATase PF00117.28 EGC35907.1 - 0.041 13.7 1.4 0.053 13.3 1.4 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I YtxH PF12732.7 EGC35907.1 - 0.14 12.7 0.9 0.26 11.8 0.9 1.9 1 1 0 1 1 1 0 YtxH-like protein Spt20 PF12090.8 EGC35908.1 - 1.7e-15 57.3 31.7 1.1e-14 54.6 6.4 3.2 2 1 0 2 2 2 1 Spt20 family SEP PF08059.13 EGC35908.1 - 0.0084 16.7 2.3 0.023 15.2 0.1 2.5 2 0 0 2 2 2 1 SEP domain Macoilin PF09726.9 EGC35908.1 - 0.41 9.1 10.0 0.52 8.8 10.0 1.1 1 0 0 1 1 1 0 Macoilin family CSRNP_N PF16019.5 EGC35908.1 - 3.8 7.4 7.3 6.1 6.7 7.3 1.3 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus ubiquitin PF00240.23 EGC35909.1 - 7.3e-11 41.7 0.0 7.9e-11 41.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family TBK1_ULD PF18396.1 EGC35909.1 - 0.006 16.5 0.0 0.0062 16.4 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_2 PF14560.6 EGC35909.1 - 0.0071 16.8 0.0 0.027 14.9 0.0 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain AICARFT_IMPCHas PF01808.18 EGC35910.1 - 3.4e-106 355.0 0.0 4.5e-106 354.6 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.22 EGC35910.1 - 2.1e-25 88.7 0.1 9.3e-25 86.6 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain COMM_domain PF07258.14 EGC35911.1 - 8.3e-17 61.1 0.1 1.7e-16 60.1 0.1 1.5 1 0 0 1 1 1 1 COMM domain Pho88 PF10032.9 EGC35911.1 - 0.07 12.4 0.1 0.11 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) DUF1084 PF06454.11 EGC35912.1 - 2.9e-82 276.1 18.9 3.8e-82 275.7 18.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF5084 PF16894.5 EGC35912.1 - 0.0016 18.9 1.0 0.0016 18.9 1.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF5084) Orf78 PF06024.12 EGC35912.1 - 1.5 9.2 11.3 4.6 7.6 0.7 4.0 3 1 1 4 4 4 0 Orf78 (ac78) LicD PF04991.13 EGC35913.1 - 0.087 12.9 13.0 0.13 12.4 13.0 1.2 1 0 0 1 1 1 0 LicD family Internalin_N PF12354.8 EGC35913.1 - 0.33 11.0 2.3 0.77 9.9 2.3 1.6 1 0 0 1 1 1 0 Bacterial adhesion/invasion protein N terminal EGF_2 PF07974.13 EGC35914.1 - 0.0042 17.4 9.0 0.0077 16.6 9.0 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGC35914.1 - 0.027 14.5 6.4 0.05 13.7 6.4 1.4 1 0 0 1 1 1 0 Tenascin EGF domain hEGF PF12661.7 EGC35914.1 - 4 8.2 10.5 0.75 10.5 6.8 1.8 2 0 0 2 2 2 0 Human growth factor-like EGF PLAC8 PF04749.17 EGC35915.1 - 1.2e-12 48.7 16.0 1.5e-12 48.4 16.0 1.1 1 0 0 1 1 1 1 PLAC8 family DUF383 PF04063.14 EGC35916.1 - 2e-38 132.0 0.9 2e-38 132.0 0.9 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.13 EGC35916.1 - 2.4e-15 56.1 0.0 1.6e-14 53.4 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF384) HEAT_2 PF13646.6 EGC35916.1 - 0.0031 17.9 0.0 0.8 10.1 0.0 2.7 2 1 0 2 2 2 2 HEAT repeats Cnd1 PF12717.7 EGC35916.1 - 0.023 14.7 1.5 0.046 13.8 0.5 2.0 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Rad21_Rec8_N PF04825.13 EGC35917.1 - 1.8e-38 131.0 0.1 3.7e-38 130.1 0.1 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.16 EGC35917.1 - 5.1e-05 22.5 0.1 0.0012 18.0 0.0 2.5 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein PI_PP_C PF18365.1 EGC35917.1 - 0.053 13.5 0.4 0.29 11.1 0.1 2.2 2 0 0 2 2 2 0 Phosphoinositide phosphatase C-terminal domain SLBP_RNA_bind PF15247.6 EGC35918.1 - 3.6e-25 87.9 0.2 5.6e-25 87.2 0.2 1.3 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain FHA PF00498.26 EGC35919.1 - 1.1e-15 57.7 0.0 2.6e-15 56.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC35919.1 - 0.00073 19.8 0.0 0.36 11.2 0.0 2.3 2 0 0 2 2 2 2 Inner membrane component of T3SS, cytoplasmic domain Pkinase PF00069.25 EGC35920.1 - 1.7e-63 214.5 0.0 4.8e-63 213.0 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC35920.1 - 2.1e-35 122.2 0.0 3.5e-35 121.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS PF00989.25 EGC35920.1 - 2.6e-23 82.2 0.0 4e-08 33.2 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_9 PF13426.7 EGC35920.1 - 5.2e-18 65.2 5.4 3.6e-07 30.4 0.0 4.4 3 1 0 3 3 3 3 PAS domain PAS_4 PF08448.10 EGC35920.1 - 1e-07 32.2 0.0 0.0007 19.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold Kinase-like PF14531.6 EGC35920.1 - 1.1e-06 28.2 0.0 3.6e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PAS_3 PF08447.12 EGC35920.1 - 1.2e-06 28.7 0.0 0.03 14.6 0.0 3.4 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.7 EGC35920.1 - 8.1e-06 25.7 0.0 0.42 10.7 0.0 3.4 3 0 0 3 3 3 2 PAS domain CDC45 PF02724.14 EGC35920.1 - 8.2e-05 21.1 13.6 8.2e-05 21.1 13.6 1.9 2 0 0 2 2 2 1 CDC45-like protein Kdo PF06293.14 EGC35920.1 - 0.00013 21.4 1.1 0.00032 20.1 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC35920.1 - 0.18 11.7 0.5 0.36 10.7 0.5 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family COX16 PF14138.6 EGC35921.1 - 1.1e-09 38.7 0.4 8.7e-09 35.8 0.4 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 Menin PF05053.13 EGC35923.1 - 2.5 6.4 11.7 3.3 6.0 11.7 1.1 1 0 0 1 1 1 0 Menin DUF5134 PF17197.4 EGC35925.1 - 0.59 10.0 3.2 0.41 10.5 0.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF5134) Metal_resist PF13801.6 EGC35925.1 - 4.3 7.6 7.7 5 7.3 3.2 2.7 2 1 0 2 2 2 0 Heavy-metal resistance Ninjurin PF04923.12 EGC35925.1 - 5.4 7.0 6.3 1.9 8.5 1.8 1.9 1 1 0 2 2 2 0 Ninjurin LRRNT_2 PF08263.12 EGC35925.1 - 7.4 7.0 9.2 33 4.9 0.6 3.1 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Phosphonate-bd PF12974.7 EGC35926.1 - 1.9e-20 73.5 0.0 3e-20 72.9 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.11 EGC35926.1 - 0.02 14.8 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like Rho_GDI PF02115.17 EGC35927.1 - 4e-05 23.4 0.0 4.8e-05 23.2 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor CHDCT2 PF08074.11 EGC35929.1 - 1.7 8.8 8.6 0.2 11.8 4.5 1.6 2 0 0 2 2 2 0 CHDCT2 (NUC038) domain RNA_pol_Rpb2_7 PF04560.20 EGC35929.1 - 7.8 7.0 8.1 36 4.8 0.2 3.1 2 1 1 3 3 3 0 RNA polymerase Rpb2, domain 7 Ras PF00071.22 EGC35930.1 - 2e-65 219.3 0.2 2.3e-65 219.1 0.2 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35930.1 - 3.1e-35 121.0 0.0 4.8e-35 120.4 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35930.1 - 1.8e-14 53.6 0.1 2.2e-14 53.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC35930.1 - 6.9e-06 25.7 0.2 2.7e-05 23.8 0.1 1.9 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGC35930.1 - 2.8e-05 23.6 0.0 3.5e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC35930.1 - 0.00012 22.1 0.0 0.00034 20.7 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC35930.1 - 0.00065 19.6 0.2 0.26 11.2 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase SRPRB PF09439.10 EGC35930.1 - 0.0046 16.4 0.0 0.0071 15.8 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit DUF3963 PF13124.6 EGC35930.1 - 0.0084 16.1 0.2 0.019 14.9 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3963) MCM PF00493.23 EGC35930.1 - 0.035 13.2 0.0 0.21 10.6 0.0 1.9 2 0 0 2 2 2 0 MCM P-loop domain AAA_29 PF13555.6 EGC35930.1 - 0.05 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC35930.1 - 0.07 13.5 0.0 0.094 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.14 EGC35930.1 - 0.11 12.5 0.0 0.2 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) GATase PF00117.28 EGC35931.1 - 0.036 13.9 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Ras PF00071.22 EGC35932.1 - 3.2e-56 189.4 0.1 3.9e-56 189.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC35932.1 - 2.8e-33 114.7 0.1 4.1e-33 114.1 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC35932.1 - 5.8e-13 48.7 0.1 6.8e-13 48.4 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC35932.1 - 0.0035 16.7 0.0 0.0042 16.5 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC35932.1 - 0.014 15.0 0.0 0.017 14.7 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC35932.1 - 0.021 14.8 0.2 1.3 8.9 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase MMR_HSR1 PF01926.23 EGC35932.1 - 0.03 14.4 0.3 0.074 13.1 0.0 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase NTPase_1 PF03266.15 EGC35932.1 - 0.096 12.6 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 NTPase EF-hand_7 PF13499.6 EGC35933.1 - 7.7e-17 61.5 6.5 3.4e-10 40.2 0.9 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC35933.1 - 7.1e-16 56.5 10.5 2.8e-05 23.4 0.3 4.1 4 1 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGC35933.1 - 1.5e-15 55.7 6.2 6.7e-05 22.5 0.1 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.6 EGC35933.1 - 5.9e-15 54.0 6.7 1.2e-05 24.6 0.2 4.2 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.6 EGC35933.1 - 7.1e-12 45.0 4.1 0.00024 20.9 0.0 3.5 2 2 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC35933.1 - 4.5e-10 39.8 1.7 1.3e-05 25.4 0.6 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF5109 PF17134.4 EGC35933.1 - 0.013 15.4 1.1 2.8 7.9 0.1 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF5109) EF-hand_4 PF12763.7 EGC35933.1 - 0.35 10.8 6.1 1.5 8.8 1.8 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.27 EGC35934.1 - 7e-68 224.6 0.8 5.7e-22 77.5 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.22 EGC35935.1 - 3.3e-09 36.6 4.8 5.2e-07 29.4 0.1 3.8 4 0 0 4 4 4 2 Ras family Roc PF08477.13 EGC35935.1 - 1.2e-05 25.5 1.3 0.33 11.2 0.1 3.7 1 1 1 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Aldedh PF00171.22 EGC35935.1 - 0.19 10.2 0.0 0.34 9.4 0.0 1.3 1 0 0 1 1 1 0 Aldehyde dehydrogenase family Enolase_C PF00113.22 EGC35938.1 - 1.1e-124 415.6 0.0 1.4e-124 415.2 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.16 EGC35938.1 - 2.7e-59 199.0 0.1 4.3e-59 198.4 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MR_MLE_C PF13378.6 EGC35938.1 - 7.2e-09 35.5 0.0 1.2e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 Enolase C-terminal domain-like MAAL_C PF07476.11 EGC35938.1 - 8.9e-05 21.8 0.2 0.00038 19.7 0.0 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus DUF2273 PF10031.9 EGC35939.1 - 0.0066 16.4 2.4 0.012 15.6 2.4 1.4 1 0 0 1 1 1 1 Small integral membrane protein (DUF2273) FAM196 PF15265.6 EGC35939.1 - 2.6 7.4 42.9 4.2 6.8 42.9 1.2 1 0 0 1 1 1 0 FAM196 family Capsid_NCLDV PF04451.12 EGC35941.1 - 0.0063 16.3 0.1 0.0077 16.0 0.1 1.1 1 0 0 1 1 1 1 Large eukaryotic DNA virus major capsid protein ATP-synt_ab PF00006.25 EGC35942.1 - 2.2e-108 360.8 0.0 3.1e-108 360.3 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_Xtn PF16886.5 EGC35942.1 - 1.1e-44 151.2 0.0 1.8e-44 150.4 0.0 1.4 1 0 0 1 1 1 1 ATPsynthase alpha/beta subunit N-term extension ATP-synt_ab_N PF02874.23 EGC35942.1 - 2.4e-16 60.0 1.4 1.6e-15 57.3 1.0 2.6 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain DUF150_C PF17384.2 EGC35942.1 - 0.16 12.2 0.1 17 5.7 0.0 3.0 3 0 0 3 3 3 0 RimP C-terminal SH3 domain LSM PF01423.22 EGC35943.1 - 2.8e-17 62.1 0.4 4e-17 61.7 0.4 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC35943.1 - 0.0015 18.6 0.0 0.0021 18.2 0.0 1.2 1 0 0 1 1 1 1 Ataxin 2 SM domain Feld-I_B PF09252.10 EGC35943.1 - 0.027 14.4 0.0 0.036 14.0 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Rad52_Rad22 PF04098.15 EGC35944.1 - 2.5e-31 108.7 1.0 3.9e-31 108.0 1.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Mgm101p PF06420.12 EGC35944.1 - 0.1 12.1 0.0 0.15 11.6 0.0 1.3 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 AAA_14 PF13173.6 EGC35945.1 - 0.0033 17.5 0.3 0.012 15.7 0.3 2.2 1 1 0 1 1 1 1 AAA domain ATPase_2 PF01637.18 EGC35945.1 - 0.0088 16.0 0.6 0.024 14.6 0.1 1.7 1 1 0 2 2 2 1 ATPase domain predominantly from Archaea ATPase PF06745.13 EGC35945.1 - 0.0092 15.3 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 KaiC TFIIA PF03153.13 EGC35945.1 - 0.014 15.4 4.5 0.016 15.2 4.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Rad17 PF03215.15 EGC35945.1 - 0.055 13.4 1.6 2.3 8.1 0.0 3.1 2 1 0 3 3 3 0 Rad17 P-loop domain AAA_24 PF13479.6 EGC35945.1 - 0.14 11.9 0.5 0.27 11.0 0.5 1.6 1 1 0 1 1 1 0 AAA domain Fer2_3 PF13085.6 EGC35945.1 - 0.15 12.1 0.7 0.3 11.1 0.0 1.9 2 1 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AAA_23 PF13476.6 EGC35945.1 - 4.9 7.6 12.8 1.3e+02 3.0 12.8 2.6 1 1 0 1 1 1 0 AAA domain HMG_box PF00505.19 EGC35946.1 - 5.8e-06 26.6 5.8 5.8e-06 26.6 5.8 3.6 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC35946.1 - 9.5e-05 22.9 3.1 9.5e-05 22.9 3.1 4.2 4 0 0 4 4 4 1 HMG-box domain TFIIA PF03153.13 EGC35946.1 - 0.012 15.6 44.8 0.017 15.1 44.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DIRP PF06584.13 EGC35947.1 - 1.8e-15 57.0 3.2 1.8e-15 57.0 3.2 3.1 2 0 0 2 2 2 1 DIRP DUF5320 PF17253.2 EGC35947.1 - 0.78 10.8 2.2 4.5 8.4 2.2 2.4 1 0 0 1 1 1 0 Family of unknown function (DUF5320) ACOX PF01756.19 EGC35948.1 - 3.4e-35 121.2 0.3 6.2e-35 120.4 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.19 EGC35948.1 - 2.5e-22 78.9 0.0 5.1e-22 77.9 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.24 EGC35948.1 - 0.00034 20.8 0.0 0.00072 19.8 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DapH_N PF08503.10 EGC35949.1 - 0.041 14.1 0.1 0.099 12.9 0.0 1.6 1 1 1 2 2 2 0 Tetrahydrodipicolinate succinyltransferase N-terminal VirDNA-topo-I_N PF09266.10 EGC35950.1 - 0.0062 16.7 0.3 0.019 15.1 0.3 1.8 1 0 0 1 1 1 1 Viral DNA topoisomerase I, N-terminal Mga PF05043.13 EGC35950.1 - 0.022 15.3 0.2 0.07 13.7 0.2 1.9 1 0 0 1 1 1 0 Mga helix-turn-helix domain Rho_RNA_bind PF07497.12 EGC35950.1 - 0.059 13.2 0.1 2.1 8.3 0.0 2.9 3 0 0 3 3 3 0 Rho termination factor, RNA-binding domain EGF_2 PF07974.13 EGC35950.1 - 0.57 10.6 12.0 1.4 9.4 12.0 1.7 1 0 0 1 1 1 0 EGF-like domain Sulfate_transp PF00916.20 EGC35951.1 - 1.4e-102 343.3 25.4 1.8e-102 343.0 25.4 1.1 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGC35951.1 - 3.1e-18 65.5 0.1 6e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 STAS domain XRCC4 PF06632.12 EGC35952.1 - 0.0043 16.0 2.1 0.0043 16.0 2.1 1.8 2 0 0 2 2 2 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4770 PF15994.5 EGC35952.1 - 1.4 9.1 6.9 0.093 13.0 1.2 1.9 1 1 0 2 2 2 0 Domain of unknown function (DUF4770) NmrA PF05368.13 EGC35953.1 - 9.5e-15 54.8 0.0 6.9e-14 52.0 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC35953.1 - 2.3e-13 50.4 0.0 3.8e-12 46.5 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Semialdhyde_dh PF01118.24 EGC35953.1 - 6.6e-05 23.3 0.0 0.00016 22.1 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGC35953.1 - 0.00018 21.0 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGC35953.1 - 0.00034 20.9 0.0 0.00056 20.2 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain 3Beta_HSD PF01073.19 EGC35953.1 - 0.003 16.6 0.0 0.081 11.9 0.0 2.7 2 1 1 3 3 3 1 3-beta hydroxysteroid dehydrogenase/isomerase family DapB_N PF01113.20 EGC35953.1 - 0.094 12.8 0.0 0.17 12.0 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.18 EGC35953.1 - 0.13 12.5 0.0 0.2 11.9 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain Polysacc_synt_2 PF02719.15 EGC35953.1 - 0.16 11.0 0.0 0.24 10.5 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Tenui_NS4 PF03300.13 EGC35954.1 - 0.00043 19.8 0.0 0.00064 19.2 0.0 1.2 1 0 0 1 1 1 1 Tenuivirus non-structural, movement protein NS4 GAF_2 PF13185.6 EGC35954.1 - 0.057 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 GAF domain Profilin PF00235.19 EGC35955.1 - 2.9e-33 114.8 0.3 8.3e-33 113.4 0.3 1.9 1 1 0 1 1 1 1 Profilin PhoLip_ATPase_C PF16212.5 EGC35956.1 - 4.7e-67 226.3 24.8 4.7e-67 226.3 24.8 1.9 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC35956.1 - 6.1e-22 77.1 9.2 1e-21 76.4 4.1 3.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGC35956.1 - 7.5e-11 42.0 3.0 4.2e-10 39.6 0.3 3.0 3 0 0 3 3 3 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC35956.1 - 5.3e-08 33.4 0.0 0.0019 18.5 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGC35956.1 - 3.6e-07 29.9 0.9 3.6e-07 29.9 0.9 2.7 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGC35956.1 - 3e-05 23.9 1.3 3e-05 23.9 1.3 3.6 3 1 1 4 4 4 1 haloacid dehalogenase-like hydrolase PIG-P PF08510.12 EGC35956.1 - 4.6 7.2 9.2 19 5.2 9.2 2.1 1 0 0 1 1 1 0 PIG-P Rhomboid PF01694.22 EGC35957.1 - 1.3e-13 51.2 5.7 1.3e-13 51.2 5.7 1.8 2 0 0 2 2 2 1 Rhomboid family DER1 PF04511.15 EGC35957.1 - 0.12 12.3 11.3 0.32 10.9 11.3 2.0 1 1 0 1 1 1 0 Der1-like family FNIP PF05725.12 EGC35958.1 - 4.2e-24 84.4 62.5 1.5e-11 44.3 5.5 11.6 9 3 2 11 11 11 10 FNIP Repeat Glyco_hydro_65C PF03633.15 EGC35958.1 - 0.036 14.0 0.7 0.68 9.9 0.0 3.2 4 0 0 4 4 4 0 Glycosyl hydrolase family 65, C-terminal domain DUF1576 PF07613.11 EGC35960.1 - 0.004 16.7 0.1 0.0046 16.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1576) Adeno_E3_CR2 PF02439.15 EGC35960.1 - 0.099 12.4 0.1 0.16 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FNIP PF05725.12 EGC35961.1 - 1.5e-23 82.7 31.6 2.3e-13 50.1 2.4 11.8 7 5 3 10 10 10 7 FNIP Repeat LRR_8 PF13855.6 EGC35961.1 - 0.029 14.1 14.3 0.22 11.3 2.8 5.9 6 1 0 6 6 6 0 Leucine rich repeat Glyco_hydro_65C PF03633.15 EGC35961.1 - 0.097 12.6 0.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 65, C-terminal domain Strep_SA_rep PF06696.11 EGC35962.1 - 0.49 10.5 2.5 4.1 7.5 0.7 2.9 2 0 0 2 2 2 0 Streptococcal surface antigen repeat Brr6_like_C_C PF10104.9 EGC35963.1 - 0.75 9.6 6.3 0.45 10.3 0.8 2.4 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain Tim17 PF02466.19 EGC35964.1 - 0.00044 20.6 4.8 0.0015 18.9 5.0 1.8 1 1 1 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family LETM1 PF07766.13 EGC35964.1 - 0.068 12.5 2.3 0.099 12.0 2.3 1.1 1 0 0 1 1 1 0 LETM1-like protein CCDC32 PF14989.6 EGC35964.1 - 0.081 12.9 5.3 0.14 12.2 5.3 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing 32 UPF0154 PF03672.13 EGC35964.1 - 0.1 12.7 1.2 0.34 11.0 0.0 2.5 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) tRNA-synt_2d PF01409.20 EGC35965.1 - 3.4e-89 298.5 0.2 6.3e-89 297.7 0.1 1.5 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) PheRS_DBD3 PF18553.1 EGC35965.1 - 7.8e-10 38.9 0.1 2.1e-09 37.5 0.1 1.8 1 0 0 1 1 1 1 PheRS DNA binding domain 3 tRNA_synthFbeta PF17759.1 EGC35965.1 - 2.5e-07 30.3 0.0 0.00037 20.0 0.0 2.4 2 0 0 2 2 2 2 Phenylalanyl tRNA synthetase beta chain CLM domain tRNA-synt_2 PF00152.20 EGC35965.1 - 0.00012 21.3 0.7 0.00059 19.0 0.0 2.3 3 0 0 3 3 3 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGC35965.1 - 0.0037 17.3 0.0 0.0067 16.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) PheRS_DBD2 PF18554.1 EGC35965.1 - 2.4 8.2 5.6 3.5 7.7 1.1 3.0 2 1 1 3 3 3 0 PheRS DNA binding domain 2 Pkinase_Tyr PF07714.17 EGC35966.1 - 1.2e-61 208.3 0.0 1.6e-61 207.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC35966.1 - 1.1e-50 172.5 0.0 1.6e-50 171.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.6 EGC35966.1 - 4.3e-05 23.0 0.0 8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC35966.1 - 0.00013 21.1 2.5 0.0081 15.1 2.5 2.1 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGC35966.1 - 0.00031 20.4 2.6 0.0086 15.7 0.2 2.6 1 1 0 2 2 2 1 RIO1 family APH PF01636.23 EGC35966.1 - 0.00089 19.3 0.0 0.004 17.1 0.0 1.7 1 1 0 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC35966.1 - 0.0013 18.1 0.0 0.0018 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC35966.1 - 0.013 14.3 0.0 0.022 13.5 0.0 1.3 1 0 0 1 1 1 0 Fungal protein kinase FTA2 PF13095.6 EGC35966.1 - 0.064 12.9 0.6 7.5 6.1 0.1 2.3 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 LIM PF00412.22 EGC35967.1 - 9.1e-16 57.8 15.4 4.1e-10 39.7 7.4 2.1 2 0 0 2 2 2 2 LIM domain Zn_Tnp_IS1595 PF12760.7 EGC35967.1 - 0.053 13.5 1.7 0.053 13.5 1.7 2.7 2 2 0 2 2 2 0 Transposase zinc-ribbon domain DUF1451 PF07295.11 EGC35967.1 - 0.11 12.5 6.4 0.15 12.1 4.7 2.0 1 1 1 2 2 2 0 Zinc-ribbon containing domain zf-SNAP50_C PF12251.8 EGC35967.1 - 1.4 8.5 13.7 3.4 7.3 5.4 2.2 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal DUF5082 PF16888.5 EGC35968.1 - 0.0095 16.2 10.4 0.0095 16.2 10.4 3.0 3 1 0 3 3 3 1 Domain of unknown function (DUF5082) bZIP_1 PF00170.21 EGC35968.1 - 0.033 14.3 2.5 0.11 12.7 1.6 2.4 1 1 1 2 2 2 0 bZIP transcription factor ABC_tran_CTD PF16326.5 EGC35968.1 - 0.1 12.9 1.2 0.28 11.4 1.2 1.8 1 0 0 1 1 1 0 ABC transporter C-terminal domain TFIIA PF03153.13 EGC35968.1 - 3.9 7.4 33.3 5.4 6.9 33.3 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit TSC22 PF01166.18 EGC35968.1 - 7.1 7.0 9.9 2.1 8.7 2.0 3.3 2 1 1 3 3 3 0 TSC-22/dip/bun family Mersacidin PF16934.5 EGC35969.1 - 0.0031 17.2 1.3 0.0043 16.8 0.9 1.5 1 1 0 1 1 1 1 Two-component Enterococcus faecalis cytolysin (EFC) DUF4442 PF14539.6 EGC35969.1 - 0.061 13.5 0.1 0.081 13.1 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) MFS_4 PF06779.14 EGC35970.1 - 0.0011 18.4 0.3 0.0016 17.9 0.3 1.2 1 0 0 1 1 1 1 Uncharacterised MFS-type transporter YbfB DUF2530 PF10745.9 EGC35970.1 - 0.34 11.2 1.9 0.7 10.2 1.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2530) RED_N PF07808.13 EGC35972.1 - 6e-22 78.4 22.1 7.8e-22 78.0 8.8 4.9 4 1 1 5 5 5 2 RED-like protein N-terminal region DUF4306 PF14154.6 EGC35972.1 - 0.23 11.7 0.1 0.51 10.5 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4306) NUDIX PF00293.28 EGC35973.1 - 7.5e-13 48.7 0.0 1.4e-12 47.8 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain zf-Di19 PF05605.12 EGC35973.1 - 0.00058 20.1 5.8 0.0024 18.1 5.8 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding Zn-C2H2_12 PF18112.1 EGC35973.1 - 0.026 15.0 3.4 0.61 10.6 0.0 2.6 2 0 0 2 2 2 0 Autophagy receptor zinc finger-C2H2 domain Prok-RING_4 PF14447.6 EGC35973.1 - 0.11 12.4 2.5 8.1 6.4 0.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 DUF3873 PF12989.7 EGC35973.1 - 0.11 12.9 0.1 0.26 11.7 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) TruD PF01142.18 EGC35975.1 - 1.4e-78 264.6 0.6 2.2e-74 250.7 0.1 2.6 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Not3 PF04065.15 EGC35976.1 - 4.5e-68 229.1 18.9 4.5e-68 229.1 18.9 3.5 2 1 1 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.18 EGC35976.1 - 7.4e-40 136.1 5.5 7.4e-40 136.1 5.5 5.2 4 2 0 4 4 4 1 NOT2 / NOT3 / NOT5 family VPS9 PF02204.18 EGC35977.1 - 3.1e-27 94.8 1.6 4.7e-27 94.2 1.6 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DNA_RNApol_7kD PF03604.13 EGC35978.1 - 2.1e-16 59.3 7.2 2.6e-16 59.0 7.2 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit MCM_OB PF17207.3 EGC35978.1 - 0.0028 17.5 0.9 0.0033 17.3 0.9 1.0 1 0 0 1 1 1 1 MCM OB domain DZR PF12773.7 EGC35978.1 - 0.056 13.5 2.6 0.069 13.2 2.6 1.1 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_13 PF09855.9 EGC35978.1 - 0.1 12.8 0.6 0.1 12.8 0.6 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) ADK_lid PF05191.14 EGC35978.1 - 0.16 12.0 3.3 0.28 11.2 3.3 1.5 1 0 0 1 1 1 0 Adenylate kinase, active site lid Mito_carr PF00153.27 EGC35979.1 - 9.3e-71 233.9 0.4 3.5e-23 81.3 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Spc7 PF08317.11 EGC35979.1 - 0.19 10.6 8.5 0.32 9.8 8.5 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein GrpE PF01025.19 EGC35979.1 - 0.45 10.2 7.9 0.72 9.5 7.9 1.4 1 0 0 1 1 1 0 GrpE DED PF01335.21 EGC35981.1 - 0.025 14.9 0.3 0.075 13.3 0.3 1.9 1 0 0 1 1 1 0 Death effector domain EF-hand_4 PF12763.7 EGC35982.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.4 4 0 0 4 4 4 0 Cytoskeletal-regulatory complex EF hand WD40 PF00400.32 EGC35983.1 - 8.5e-15 54.9 14.0 0.00014 22.5 0.1 4.8 4 0 0 4 4 4 4 WD domain, G-beta repeat Ge1_WD40 PF16529.5 EGC35983.1 - 0.013 14.5 0.0 0.11 11.5 0.0 2.0 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein BUD22 PF09073.10 EGC35983.1 - 0.45 9.8 50.9 0.031 13.6 37.6 2.2 2 0 0 2 2 2 0 BUD22 ETRAMP PF09716.10 EGC35984.1 - 0.014 15.5 1.9 0.049 13.7 1.9 2.0 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2034 PF10356.9 EGC35984.1 - 0.08 12.4 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2034) DDE_Tnp_4 PF13359.6 EGC35985.1 - 0.0001 22.0 2.0 0.00013 21.7 2.0 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC35985.1 - 0.018 14.7 2.2 0.03 14.0 0.2 1.9 1 1 1 2 2 2 0 Transposase DDE domain CRAL_TRIO PF00650.20 EGC35986.1 - 3.9e-26 91.7 0.5 5.8e-26 91.1 0.5 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.6 EGC35986.1 - 0.00033 20.8 0.2 0.00051 20.2 0.2 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain G8 PF10162.9 EGC35987.1 - 0.046 13.8 6.2 1.5 8.9 0.4 3.8 2 1 1 3 3 3 0 G8 domain Castor_Poll_mid PF06241.12 EGC35987.1 - 0.064 13.2 0.4 1.5 8.8 0.1 3.2 3 1 0 3 3 3 0 Castor and Pollux, part of voltage-gated ion channel G8 PF10162.9 EGC35988.1 - 0.027 14.6 0.3 6.9 6.8 0.1 3.1 2 1 0 2 2 2 0 G8 domain Ctr PF04145.15 EGC35988.1 - 0.049 14.2 0.0 0.14 12.7 0.0 1.8 2 0 0 2 2 2 0 Ctr copper transporter family DUF4488 PF14869.6 EGC35988.1 - 0.75 9.7 4.9 1.1 9.2 1.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4488) SURF6 PF04935.12 EGC35989.1 - 0.15 11.8 1.4 3.8 7.2 1.4 2.0 1 1 0 1 1 1 0 Surfeit locus protein 6 IBR PF01485.21 EGC35990.1 - 6.3e-23 80.8 44.5 7.6e-14 51.7 11.4 4.5 3 1 1 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGC35990.1 - 6.1e-07 29.7 6.6 6.1e-07 29.7 6.6 4.2 3 1 1 4 4 4 1 Ring finger domain zf-RING_5 PF14634.6 EGC35990.1 - 0.00014 21.7 6.0 0.00014 21.7 6.0 3.3 3 1 1 4 4 4 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC35990.1 - 0.00035 20.5 4.8 0.00035 20.5 4.8 3.5 3 1 0 3 3 3 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC35990.1 - 0.0013 18.5 2.3 0.0013 18.5 2.3 4.2 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC35990.1 - 0.0018 18.1 7.5 0.0018 18.1 7.5 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGC35990.1 - 0.02 15.1 4.4 0.02 15.1 4.4 3.6 3 1 0 3 3 3 0 FANCL C-terminal domain zf-RING_11 PF17123.5 EGC35990.1 - 0.044 13.5 6.9 0.16 11.8 6.9 2.1 1 0 0 1 1 1 0 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC35990.1 - 9.5 6.5 31.8 0.11 12.7 2.4 4.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING ATG27 PF09451.10 EGC35991.1 - 4.6e-05 23.4 2.5 6.1e-05 23.0 2.5 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 SpvB PF03534.13 EGC35991.1 - 0.0085 15.3 0.1 0.012 14.9 0.1 1.1 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein SAM_2 PF07647.17 EGC35992.1 - 7.7e-10 38.7 0.1 1.8e-09 37.6 0.1 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC35992.1 - 1.9e-09 37.8 0.0 3.7e-09 36.9 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EGF_2 PF07974.13 EGC35993.1 - 2.5 8.6 10.8 8 6.9 10.8 1.9 1 0 0 1 1 1 0 EGF-like domain Beta-APP PF03494.13 EGC35993.1 - 5.4 6.9 5.0 12 5.8 4.4 1.8 2 0 0 2 2 2 0 Beta-amyloid peptide (beta-APP) RCC1 PF00415.18 EGC35994.1 - 1.7e-91 300.7 14.7 3.2e-14 53.3 0.1 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC35994.1 - 5.2e-38 128.1 31.6 1.1e-09 37.9 0.7 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat Androgen_recep PF02166.16 EGC35994.1 - 2.7 6.7 16.5 3.8 6.3 6.7 2.6 2 0 0 2 2 2 0 Androgen receptor Aldedh PF00171.22 EGC35996.1 - 3e-104 349.1 0.0 3.7e-104 348.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Peptidase_M1 PF01433.20 EGC35999.1 - 3e-68 229.7 6.2 5.7e-68 228.7 6.2 1.5 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGC35999.1 - 5e-48 164.3 0.6 3e-47 161.7 0.2 2.0 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGC35999.1 - 1.7e-42 145.7 2.5 2.2e-42 145.4 1.4 1.8 2 0 0 2 2 2 1 Peptidase M1 N-terminal domain Erf4 PF10256.9 EGC36000.1 - 0.0017 18.4 0.2 0.0057 16.7 0.2 1.9 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family SNARE_assoc PF09335.11 EGC36000.1 - 0.0075 16.8 0.3 0.014 15.9 0.2 1.5 1 1 0 1 1 1 1 SNARE associated Golgi protein Reprolysin_5 PF13688.6 EGC36000.1 - 0.056 13.6 0.5 0.084 13.0 0.5 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 DUF4520 PF15016.6 EGC36000.1 - 0.29 11.2 1.6 0.52 10.4 0.1 2.3 3 1 0 3 3 3 0 Domain of unknown function (DUF4520) Aminotran_3 PF00202.21 EGC36001.1 - 7.3e-113 377.3 0.0 9.3e-113 376.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_5 PF00266.19 EGC36001.1 - 0.00027 20.0 0.0 0.0026 16.8 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGC36001.1 - 0.00028 20.2 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGC36001.1 - 0.14 11.5 0.0 0.52 9.5 0.0 1.8 1 1 0 1 1 1 0 Beta-eliminating lyase DCP1 PF06058.13 EGC36004.1 - 7.9e-39 132.2 0.6 1.2e-38 131.6 0.6 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family mRNA_decap_C PF16741.5 EGC36004.1 - 0.004 16.4 0.1 0.0094 15.2 0.1 1.7 1 0 0 1 1 1 1 mRNA-decapping enzyme C-terminus Hamartin PF04388.12 EGC36004.1 - 0.027 13.2 10.1 0.033 12.9 10.1 1.1 1 0 0 1 1 1 0 Hamartin protein Roughex PF06020.11 EGC36004.1 - 2.2 7.3 5.3 1.8 7.6 0.0 2.3 2 0 0 2 2 2 0 Drosophila roughex protein LigB PF02900.18 EGC36006.1 - 5.7e-34 117.4 0.0 6.6e-34 117.2 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Bystin PF05291.11 EGC36007.1 - 1.5e-119 398.7 0.8 1.5e-119 398.7 0.8 1.7 2 0 0 2 2 2 1 Bystin SRI PF08236.11 EGC36007.1 - 0.0092 16.1 0.3 0.073 13.2 0.0 2.3 2 0 0 2 2 2 1 SRI (Set2 Rpb1 interacting) domain RRN3 PF05327.11 EGC36007.1 - 5.3 5.5 9.2 10 4.5 9.2 1.4 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 HA2 PF04408.23 EGC36008.1 - 4.9e-28 97.6 0.0 4.9e-28 97.6 0.0 4.6 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC36008.1 - 2.7e-16 59.7 0.0 7.8e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGC36008.1 - 1.8e-08 34.7 0.0 1.8e-08 34.7 0.0 3.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC36008.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 2.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase AAA_22 PF13401.6 EGC36008.1 - 0.11 12.8 0.0 0.11 12.8 0.0 2.9 3 0 0 3 3 3 0 AAA domain FtsK_SpoIIIE PF01580.18 EGC36008.1 - 0.61 9.4 0.0 0.61 9.4 0.0 3.4 4 0 0 4 4 4 0 FtsK/SpoIIIE family PEPcase PF00311.17 EGC36009.1 - 4.7e-277 921.3 0.0 5.7e-277 921.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.6 EGC36009.1 - 0.0092 14.5 0.0 0.022 13.3 0.0 1.5 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase VitK2_biosynth PF02621.14 EGC36009.1 - 0.083 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 Menaquinone biosynthesis DUF4286 PF14114.6 EGC36010.1 - 5.4e-23 81.3 0.0 6.4e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) NurA PF09376.10 EGC36012.1 - 0.079 12.6 0.1 0.14 11.9 0.1 1.4 1 1 0 1 1 1 0 NurA domain MoCF_biosynth PF00994.24 EGC36013.1 - 1e-50 171.1 1.0 3.4e-25 88.4 0.1 2.6 3 0 0 3 3 3 2 Probable molybdopterin binding domain MoeA_N PF03453.17 EGC36013.1 - 2.4e-40 137.9 0.1 8.4e-40 136.1 0.0 1.9 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.15 EGC36013.1 - 1.5e-14 53.9 0.0 3.7e-14 52.6 0.0 1.7 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) SelP_N PF04592.14 EGC36013.1 - 1.9 7.9 7.7 3.3 7.1 7.7 1.3 1 0 0 1 1 1 0 Selenoprotein P, N terminal region LIM PF00412.22 EGC36014.1 - 2.8e-11 43.4 10.0 4.5e-11 42.8 10.0 1.3 1 0 0 1 1 1 1 LIM domain TDH PF03347.13 EGC36014.1 - 0.088 12.4 0.4 0.27 10.8 0.1 1.9 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin DUF2175 PF09943.9 EGC36014.1 - 0.54 10.6 4.7 1.1 9.7 4.7 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2175) MFS_1_like PF12832.7 EGC36015.1 - 6.4e-115 384.1 14.2 7.9e-115 383.8 14.2 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGC36015.1 - 5.3e-28 98.0 13.6 5.5e-24 84.7 1.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGC36015.1 - 1.6e-11 43.9 25.4 5.8e-11 42.0 10.2 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 EGC36015.1 - 2.7e-07 29.7 9.1 2.7e-07 29.7 9.1 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter Exonuc_VII_L PF02601.15 EGC36016.1 - 0.63 9.6 16.7 0.74 9.3 16.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit CENP-K PF11802.8 EGC36016.1 - 3.7 7.0 36.9 0.14 11.7 23.3 2.0 1 1 1 2 2 2 0 Centromere-associated protein K PI3_PI4_kinase PF00454.27 EGC36017.1 - 7.9e-38 130.7 0.0 4.5e-29 102.0 0.0 3.7 4 1 1 5 5 5 2 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC36017.1 - 0.00018 21.0 0.2 0.00053 19.4 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) DUF4135 PF13575.6 EGC36017.1 - 0.0078 15.6 1.4 0.01 15.2 0.0 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4135) U3snoRNP10 PF12397.8 EGC36017.1 - 0.04 14.3 0.5 0.41 11.0 0.8 2.6 2 0 0 2 2 2 0 U3 small nucleolar RNA-associated protein 10 OTU PF02338.19 EGC36018.1 - 6.4e-12 46.1 0.1 8.2e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease FTCD_N PF07837.12 EGC36019.1 - 2.9e-74 248.6 0.0 4.5e-74 248.0 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.12 EGC36019.1 - 2e-65 220.0 0.0 3.3e-65 219.3 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.14 EGC36019.1 - 3.5e-64 215.2 0.0 6e-64 214.4 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain PheRS_DBD2 PF18554.1 EGC36019.1 - 0.15 12.1 0.2 0.35 10.9 0.2 1.6 1 0 0 1 1 1 0 PheRS DNA binding domain 2 RNB PF00773.19 EGC36020.1 - 1.3e-12 47.7 19.0 6.2e-12 45.5 9.1 3.5 2 1 1 3 3 3 2 RNB domain SRI PF08236.11 EGC36020.1 - 1.1 9.5 6.5 1.7 8.9 0.8 3.5 3 0 0 3 3 3 0 SRI (Set2 Rpb1 interacting) domain CH PF00307.31 EGC36022.1 - 2.4e-29 101.7 9.6 5.6e-20 71.5 0.0 3.8 4 0 0 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC36022.1 - 2.3e-10 40.2 0.2 1.5e-09 37.5 0.1 2.4 2 0 0 2 2 2 1 CAMSAP CH domain Golgin_A5 PF09787.9 EGC36022.1 - 0.00042 19.9 24.5 0.00042 19.9 24.5 2.1 1 1 1 2 2 2 1 Golgin subfamily A member 5 DUF4407 PF14362.6 EGC36022.1 - 0.0034 16.8 15.4 0.0034 16.8 15.4 2.2 1 1 0 2 2 2 1 Domain of unknown function (DUF4407) KASH_CCD PF14662.6 EGC36022.1 - 0.0086 15.9 46.5 0.031 14.1 37.9 2.4 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 or KASH THOC7 PF05615.13 EGC36022.1 - 0.018 15.4 7.3 0.018 15.4 7.3 3.5 1 1 2 3 3 3 0 Tho complex subunit 7 BLOC1_2 PF10046.9 EGC36022.1 - 0.023 15.0 9.3 0.023 15.0 9.3 3.6 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 APG6_N PF17675.1 EGC36022.1 - 0.095 13.2 47.8 0.25 11.9 18.9 3.1 1 1 2 3 3 3 0 Apg6 coiled-coil region Sec34 PF04136.15 EGC36022.1 - 0.13 12.1 31.0 0.43 10.5 6.2 3.1 1 1 2 3 3 3 0 Sec34-like family TraF_2 PF13729.6 EGC36022.1 - 0.21 11.0 11.6 1.7 7.9 1.7 2.5 2 0 0 2 2 2 0 F plasmid transfer operon, TraF, protein ATG16 PF08614.11 EGC36022.1 - 0.25 11.5 43.2 0.3 11.3 12.5 2.8 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) HIP1_clath_bdg PF16515.5 EGC36022.1 - 0.31 11.7 42.7 0.053 14.1 8.9 3.3 1 1 2 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 TPR_MLP1_2 PF07926.12 EGC36022.1 - 0.37 10.9 42.2 0.36 10.9 6.8 3.2 1 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein DUF812 PF05667.11 EGC36022.1 - 1.4 7.7 42.8 0.055 12.4 10.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF812) HrpB7 PF09486.10 EGC36022.1 - 3.2 8.1 14.5 0.095 13.1 2.4 2.8 1 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB7) DUF5082 PF16888.5 EGC36022.1 - 3.9 7.8 41.9 2.8 8.2 1.1 3.7 2 1 0 3 3 3 0 Domain of unknown function (DUF5082) LOH1CR12 PF10158.9 EGC36022.1 - 4.2 7.4 14.6 7.7 6.5 2.6 2.5 1 1 1 2 2 2 0 Tumour suppressor protein OmpH PF03938.14 EGC36022.1 - 5 7.5 50.0 18 5.7 15.0 3.1 1 1 0 2 2 2 0 Outer membrane protein (OmpH-like) AAA_13 PF13166.6 EGC36022.1 - 6.1 5.4 38.2 3.8 6.0 36.3 1.5 1 1 0 1 1 1 0 AAA domain DUF745 PF05335.13 EGC36022.1 - 6.2 6.5 28.7 0.17 11.6 3.7 3.1 1 1 0 2 2 2 0 Protein of unknown function (DUF745) DUF4239 PF14023.6 EGC36022.1 - 6.8 6.4 12.6 9.8 5.8 3.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) UPF0242 PF06785.11 EGC36022.1 - 8 6.5 53.3 2.2 8.3 28.1 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus GAS PF13851.6 EGC36022.1 - 8.2 5.7 50.9 0.83 9.0 25.3 2.5 2 1 1 3 3 3 0 Growth-arrest specific micro-tubule binding ACR_tran PF00873.19 EGC36022.1 - 8.4 3.9 11.6 3.6 5.1 9.6 1.4 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family Atg14 PF10186.9 EGC36022.1 - 9 5.3 41.6 0.35 9.9 19.6 2.1 1 1 1 2 2 2 0 Vacuolar sorting 38 and autophagy-related subunit 14 DUF2009 PF09418.10 EGC36022.1 - 9.4 5.2 21.4 1.8 7.6 9.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2009) CPSase_L_D2 PF02786.17 EGC36023.1 - 2e-76 256.2 0.0 3.4e-76 255.4 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Biotin_carb_N PF00289.22 EGC36023.1 - 3e-46 156.5 0.0 7.4e-46 155.2 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase, N-terminal domain Biotin_carb_C PF02785.19 EGC36023.1 - 8.9e-36 122.3 0.0 2.6e-35 120.8 0.0 1.8 2 0 0 2 2 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.22 EGC36023.1 - 7.7e-16 57.7 2.8 3.6e-15 55.5 2.2 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme Dala_Dala_lig_C PF07478.13 EGC36023.1 - 5.9e-12 45.5 0.0 1.4e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.22 EGC36023.1 - 1.7e-11 44.0 0.4 4.7e-11 42.6 0.1 1.9 3 0 0 3 3 3 1 ATP-grasp domain HlyD_3 PF13437.6 EGC36023.1 - 5.9e-06 26.9 0.8 0.036 14.8 0.1 3.3 3 0 0 3 3 2 2 HlyD family secretion protein Biotin_lipoyl_2 PF13533.6 EGC36023.1 - 7.5e-06 25.7 1.2 0.0019 18.0 0.0 3.0 2 1 1 3 3 2 1 Biotin-lipoyl like RnfC_N PF13375.6 EGC36023.1 - 2.2e-05 24.3 0.4 0.00026 20.9 0.1 2.8 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain ATP-grasp_3 PF02655.14 EGC36023.1 - 6.2e-05 23.1 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain SWM_repeat PF13753.6 EGC36023.1 - 0.00012 22.2 4.4 0.0032 17.6 1.9 2.7 2 0 0 2 2 2 1 Putative flagellar system-associated repeat GARS_A PF01071.19 EGC36023.1 - 0.0035 17.1 0.0 0.0073 16.1 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain RimK PF08443.11 EGC36023.1 - 0.0044 16.7 0.0 0.025 14.2 0.0 2.0 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.6 EGC36023.1 - 0.0049 16.2 0.0 0.031 13.5 0.0 2.0 2 0 0 2 2 2 1 Sugar-transfer associated ATP-grasp GCV_H PF01597.19 EGC36023.1 - 0.013 15.4 0.1 0.032 14.1 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein HlyD_D23 PF16576.5 EGC36023.1 - 0.023 13.9 0.1 0.77 8.9 0.0 2.5 1 1 1 2 2 2 0 Barrel-sandwich domain of CusB or HlyD membrane-fusion ATP-grasp_4 PF13535.6 EGC36023.1 - 0.027 14.1 0.0 0.055 13.1 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain SCP2 PF02036.17 EGC36023.1 - 0.031 14.8 0.1 0.11 13.0 0.0 1.9 2 0 0 2 2 2 0 SCP-2 sterol transfer family Proteasome_A_N PF10584.9 EGC36023.1 - 0.18 11.5 0.0 0.41 10.4 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature GDC-P PF02347.16 EGC36024.1 - 1.2e-188 627.4 0.1 6e-177 588.8 0.1 3.0 3 0 0 3 3 3 2 Glycine cleavage system P-protein Aminotran_5 PF00266.19 EGC36024.1 - 6.7e-05 22.0 0.1 0.00074 18.6 0.1 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGC36024.1 - 0.012 14.9 0.0 0.029 13.6 0.0 1.7 1 0 0 1 1 1 0 Beta-eliminating lyase AAA_31 PF13614.6 EGC36024.1 - 0.014 15.4 0.0 0.06 13.3 0.0 2.1 1 0 0 1 1 1 0 AAA domain Aminotran_1_2 PF00155.21 EGC36025.1 - 1.2e-59 202.3 0.0 1.4e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGC36025.1 - 0.0008 18.0 0.1 0.0018 16.9 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.21 EGC36025.1 - 0.0094 15.3 0.0 0.013 14.8 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGC36025.1 - 0.012 14.6 0.1 0.041 12.8 0.1 1.8 1 1 0 1 1 1 0 Aminotransferase class-V BAR PF03114.18 EGC36026.1 - 0.011 15.4 9.1 0.12 12.0 9.2 2.3 1 1 1 2 2 2 0 BAR domain DUF4200 PF13863.6 EGC36026.1 - 0.071 13.5 9.9 1.7 9.0 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) DUF16 PF01519.16 EGC36026.1 - 3.9 8.0 9.0 1.7 9.1 3.8 2.3 1 1 0 2 2 2 0 Protein of unknown function DUF16 DHHC PF01529.20 EGC36027.1 - 6.8e-31 107.2 11.5 1.6e-30 105.9 11.5 1.6 1 0 0 1 1 1 1 DHHC palmitoyltransferase DUF4637 PF15470.6 EGC36027.1 - 1.7e-05 24.7 4.1 1.7e-05 24.7 4.1 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF4637) CDC45 PF02724.14 EGC36027.1 - 0.32 9.2 14.6 0.44 8.8 14.6 1.2 1 0 0 1 1 1 0 CDC45-like protein IGFBP PF00219.18 EGC36027.1 - 0.6 10.8 4.9 1.2 9.8 4.9 1.4 1 0 0 1 1 1 0 Insulin-like growth factor binding protein EPL1 PF10513.9 EGC36028.1 - 5.4e-14 52.9 1.7 5.4e-14 52.9 1.7 6.0 3 2 0 3 3 3 1 Enhancer of polycomb-like Response_reg PF00072.24 EGC36029.1 - 9.1e-17 61.2 0.3 2.2e-16 60.0 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain LRR_6 PF13516.6 EGC36029.1 - 9.8e-09 34.6 30.8 0.12 12.5 0.3 9.0 9 0 0 9 9 9 6 Leucine Rich repeat EF-hand_7 PF13499.6 EGC36029.1 - 0.28 11.6 1.9 1.4 9.5 0.2 2.8 2 1 0 2 2 2 0 EF-hand domain pair KH_8 PF17903.1 EGC36030.1 - 3.3e-05 23.9 0.1 8.5e-05 22.6 0.1 1.6 1 0 0 1 1 1 1 Krr1 KH1 domain KH_1 PF00013.29 EGC36030.1 - 0.004 17.0 1.8 0.004 16.9 0.3 1.8 2 0 0 2 2 2 1 KH domain p450 PF00067.22 EGC36032.1 - 6e-89 298.9 0.1 6.9e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Folliculin PF11704.8 EGC36033.1 - 5.8e-06 26.3 0.5 5.8e-06 26.3 0.5 4.8 3 2 1 4 4 4 1 Vesicle coat protein involved in Golgi to plasma membrane transport IMS PF00817.20 EGC36033.1 - 0.11 12.5 0.0 0.24 11.4 0.0 1.5 1 0 0 1 1 1 0 impB/mucB/samB family Pyr_redox_2 PF07992.14 EGC36034.1 - 1.8e-43 148.8 0.0 2.6e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_1 PF00036.32 EGC36034.1 - 1.6e-10 39.8 12.5 2.3e-05 23.6 2.1 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.6 EGC36034.1 - 2.9e-10 39.2 7.8 4.9e-05 22.9 1.4 2.9 2 0 0 2 2 2 2 EF-hand domain Pyr_redox PF00070.27 EGC36034.1 - 3.1e-10 40.5 0.0 1.8e-09 38.0 0.0 2.3 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_7 PF13499.6 EGC36034.1 - 3e-09 37.2 2.7 1e-08 35.5 2.7 2.0 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGC36034.1 - 3.9e-09 35.6 11.1 7.3e-05 22.1 1.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.6 EGC36034.1 - 6.5e-09 35.5 5.3 0.00014 21.6 0.1 2.6 2 0 0 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC36034.1 - 0.15 12.4 2.4 0.21 11.9 0.1 2.4 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DENN PF02141.21 EGC36035.1 - 8.7e-30 104.1 3.2 1.5e-29 103.3 1.5 2.4 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EGC36035.1 - 7.9e-08 32.9 0.2 3.6e-07 30.8 0.2 2.2 1 0 0 1 1 1 1 uDENN domain FNIP PF05725.12 EGC36036.1 - 2.1e-11 43.8 75.9 2.6e-06 27.5 0.4 10.1 10 3 0 11 11 11 6 FNIP Repeat FNIP PF05725.12 EGC36037.1 - 8.1e-10 38.7 18.4 1.5e-05 25.1 1.2 10.4 9 2 2 11 11 11 6 FNIP Repeat PWWP PF00855.17 EGC36038.1 - 1.2e-10 41.6 0.8 1.2e-10 41.6 0.8 3.9 4 1 1 5 5 5 1 PWWP domain MgtE_N PF03448.17 EGC36038.1 - 5.7 7.6 7.8 3.1 8.5 2.1 2.7 2 1 0 3 3 3 0 MgtE intracellular N domain Sec1 PF00995.23 EGC36039.1 - 4.4e-122 409.2 13.6 5.2e-122 409.0 13.6 1.1 1 0 0 1 1 1 1 Sec1 family V-ATPase_H_C PF11698.8 EGC36039.1 - 0.011 15.9 0.6 0.079 13.1 0.4 2.5 2 0 0 2 2 2 0 V-ATPase subunit H zf-RING_9 PF13901.6 EGC36039.1 - 2.1 8.3 3.6 3.3 7.6 0.8 2.1 2 0 0 2 2 2 0 Putative zinc-RING and/or ribbon HSBP1 PF06825.12 EGC36039.1 - 4.8 7.1 8.9 0.24 11.3 1.6 2.5 3 0 0 3 3 3 0 Heat shock factor binding protein 1 GARS_A PF01071.19 EGC36041.1 - 6.5e-75 251.2 0.0 1.3e-74 250.2 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain AIRS_C PF02769.22 EGC36041.1 - 2.5e-31 108.9 0.0 7e-31 107.5 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain GARS_N PF02844.15 EGC36041.1 - 4.8e-30 104.2 0.0 1.4e-29 102.7 0.0 1.9 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, N domain GARS_C PF02843.16 EGC36041.1 - 6.2e-27 93.7 0.0 1.3e-26 92.7 0.0 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.24 EGC36041.1 - 9.5e-15 55.0 0.9 3.2e-14 53.4 0.9 2.0 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp PF02222.22 EGC36041.1 - 3.4e-05 23.5 0.0 6.5e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.17 EGC36041.1 - 8.8e-05 22.1 0.0 0.00026 20.6 0.0 1.7 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain RimK PF08443.11 EGC36041.1 - 0.00011 21.9 0.2 0.00092 18.9 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp_3 PF02655.14 EGC36041.1 - 0.00098 19.2 0.0 0.0032 17.5 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.6 EGC36041.1 - 0.0069 16.0 0.0 0.018 14.7 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain ATPgrasp_ST PF14397.6 EGC36041.1 - 0.023 14.0 0.0 0.059 12.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp WD40 PF00400.32 EGC36042.1 - 1.8e-21 76.0 15.1 2.8e-06 28.0 0.1 7.0 7 1 0 7 7 7 5 WD domain, G-beta repeat F-box-like PF12937.7 EGC36042.1 - 2.4e-10 40.1 0.0 4.6e-10 39.2 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC36042.1 - 4.7e-07 29.5 0.0 8.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGC36042.1 - 0.00052 20.3 2.9 1.6 9.1 0.2 4.3 4 1 1 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGC36042.1 - 0.03 14.4 5.3 4.2 7.5 0.0 4.4 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region SET PF00856.28 EGC36043.1 - 1e-10 42.2 1.8 1e-10 42.2 1.8 2.3 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.11 EGC36043.1 - 1.4e-06 29.1 0.1 3e-06 28.0 0.1 1.5 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding EF-hand_1 PF00036.32 EGC36044.1 - 1.1e-12 46.5 0.8 2.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGC36044.1 - 1.7e-11 43.1 0.4 6.8e-06 25.6 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.6 EGC36044.1 - 3.6e-08 33.7 0.1 4.3e-08 33.5 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGC36044.1 - 8.4e-07 28.7 0.1 1.3e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.6 EGC36044.1 - 1.1e-05 24.7 0.8 0.0006 19.2 0.2 2.3 2 0 0 2 2 2 1 EF hand SPARC_Ca_bdg PF10591.9 EGC36044.1 - 0.0006 20.1 0.0 0.00067 20.0 0.0 1.0 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGC36044.1 - 0.014 15.7 0.0 0.019 15.3 0.0 1.1 1 0 0 1 1 1 0 EF-hand domain Glycos_transf_1 PF00534.20 EGC36045.1 - 3.8e-24 85.2 0.0 3.8e-24 85.2 0.0 2.0 2 0 0 2 2 2 1 Glycosyl transferases group 1 DUF563 PF04577.14 EGC36045.1 - 4.2e-24 85.9 0.2 2.3e-23 83.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Glycos_transf_2 PF00535.26 EGC36045.1 - 1.4e-21 77.1 0.0 1.2e-20 74.0 0.0 2.5 2 1 0 2 2 2 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.6 EGC36045.1 - 8.9e-19 68.3 0.1 1.8e-18 67.3 0.1 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC36045.1 - 8.6e-08 32.4 0.0 1.5e-07 31.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_tranf_2_3 PF13641.6 EGC36045.1 - 9.5e-06 25.7 0.0 0.00012 22.1 0.0 2.5 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.6 EGC36045.1 - 0.0044 17.0 1.0 0.029 14.3 0.6 2.4 2 1 0 2 2 2 1 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.6 EGC36045.1 - 0.0091 16.4 0.0 0.024 15.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.14 EGC36045.1 - 0.093 12.4 0.6 0.24 11.1 0.6 1.7 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase O-antigen_lig PF13425.6 EGC36045.1 - 0.8 8.4 14.9 1.3 7.7 14.9 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TBCC_N PF16752.5 EGC36046.1 - 0.057 13.9 0.9 0.057 13.9 0.9 1.9 2 0 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain FKS1_dom1 PF14288.6 EGC36046.1 - 0.25 11.7 3.0 0.29 11.5 1.9 1.7 1 1 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 SpoIIIAH PF12685.7 EGC36046.1 - 4.1 7.2 16.8 5.9 6.7 16.8 1.2 1 0 0 1 1 1 0 SpoIIIAH-like protein Cellulase PF00150.18 EGC36048.1 - 9.3e-29 100.7 7.8 1.3e-28 100.3 7.8 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-Nse PF11789.8 EGC36049.1 - 6.9e-13 48.2 0.5 6.9e-13 48.2 0.5 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.6 EGC36049.1 - 7.2e-05 22.7 1.4 0.00015 21.7 1.4 1.6 1 0 0 1 1 1 1 RING-type zinc-finger SSP160 PF06933.11 EGC36049.1 - 0.0073 14.6 0.8 0.011 14.0 0.8 1.4 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-C3HC4_2 PF13923.6 EGC36049.1 - 0.01 15.7 0.1 0.022 14.6 0.1 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.20 EGC36049.1 - 0.022 14.5 0.5 0.022 14.5 0.5 1.8 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ldh_1_C PF02866.18 EGC36050.1 - 7.1e-37 126.9 0.0 1.5e-36 125.8 0.0 1.5 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGC36050.1 - 1.4e-26 93.3 0.1 2.4e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Med10 PF09748.9 EGC36051.1 - 2.6e-25 88.7 3.7 2.6e-25 88.7 3.7 1.8 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex SKA1 PF07160.12 EGC36051.1 - 6.2 6.6 29.6 3.7 7.3 16.4 2.1 2 0 0 2 2 2 0 Spindle and kinetochore-associated protein 1 SAM_1 PF00536.30 EGC36052.1 - 0.00019 21.8 0.2 0.52 10.8 0.0 3.4 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_3 PF18016.1 EGC36052.1 - 0.00096 18.9 0.1 0.0084 15.9 0.0 2.6 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC36052.1 - 0.0036 17.4 0.4 0.36 11.0 0.1 3.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC36052.1 - 0.02 14.8 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Secretin_N_2 PF07655.13 EGC36052.1 - 0.74 10.4 15.3 0.11 13.1 5.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Orf78 PF06024.12 EGC36052.1 - 3.3 8.1 10.7 35 4.8 5.2 3.2 2 0 0 2 2 2 0 Orf78 (ac78) PAC3 PF10178.9 EGC36054.1 - 0.0053 16.9 0.1 4.5 7.5 0.0 3.1 3 0 0 3 3 3 2 Proteasome assembly chaperone 3 zf-C2H2_7 PF15269.6 EGC36054.1 - 0.52 10.4 4.1 27 4.9 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger FNIP PF05725.12 EGC36055.1 - 1.3e-15 57.3 34.3 2.1e-09 37.4 1.2 6.5 4 2 3 7 7 7 5 FNIP Repeat LRR_8 PF13855.6 EGC36055.1 - 0.51 10.1 7.8 0.48 10.2 0.1 3.7 3 0 0 3 3 3 0 Leucine rich repeat Ribosomal_L7Ae PF01248.26 EGC36056.1 - 1.8e-25 88.5 1.6 2.3e-25 88.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LRR_6 PF13516.6 EGC36059.1 - 2.9e-16 58.1 63.2 0.00098 19.0 0.2 13.3 12 0 0 12 12 12 9 Leucine Rich repeat F-box PF00646.33 EGC36059.1 - 0.013 15.3 0.0 0.053 13.4 0.0 2.0 1 0 0 1 1 1 0 F-box domain F-box-like PF12937.7 EGC36059.1 - 0.014 15.3 0.1 0.044 13.7 0.1 1.9 1 0 0 1 1 1 0 F-box-like LRR_2 PF07723.13 EGC36059.1 - 0.8 10.5 12.7 24 5.8 0.1 6.4 6 0 0 6 6 6 0 Leucine Rich Repeat CBM49 PF09478.10 EGC36060.1 - 3.9e-16 59.1 0.2 5.4e-16 58.7 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGC36061.1 - 7.6e-19 67.8 0.1 1e-18 67.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Pep_deformylase PF01327.21 EGC36062.1 - 5.1e-50 169.2 0.0 6.4e-50 168.8 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase NBD94 PF16830.5 EGC36062.1 - 0.012 15.9 0.2 0.069 13.5 0.0 2.2 2 0 0 2 2 2 0 Nucleotide-Binding Domain 94 of RH MtN3_slv PF03083.16 EGC36063.1 - 2.6e-35 120.3 14.4 1.1e-17 63.8 5.1 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange DUF3290 PF11694.8 EGC36063.1 - 0.06 13.3 3.0 0.13 12.2 3.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) MASE5 PF17178.4 EGC36063.1 - 0.7 9.7 12.6 0.026 14.4 5.0 2.0 1 1 1 2 2 2 0 Membrane-associated sensor Sortilin-Vps10 PF15902.5 EGC36064.1 - 2e-57 195.0 0.4 2.6e-57 194.6 0.4 1.1 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, Sortilin_C PF15901.5 EGC36064.1 - 2.4e-26 93.1 2.3 3.5e-26 92.6 2.3 1.2 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGC36064.1 - 2.9e-06 26.5 25.5 0.23 11.6 0.1 7.9 8 0 0 8 8 8 4 BNR/Asp-box repeat 4HBT PF03061.22 EGC36065.1 - 1.4e-11 44.6 0.0 1.9e-11 44.1 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Rcd1 PF04078.13 EGC36066.1 - 1.8e-93 312.6 4.1 2e-93 312.4 4.1 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FPL PF09758.9 EGC36066.1 - 0.0014 18.7 3.6 0.0025 17.8 0.6 2.5 3 1 0 3 3 3 1 Uncharacterised conserved protein DEAD PF00270.29 EGC36067.1 - 8e-41 139.7 2.2 1.8e-40 138.6 2.2 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC36067.1 - 1.4e-30 105.8 1.6 4.3e-29 101.1 0.2 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36067.1 - 1.3e-09 38.3 0.1 1.3e-09 38.3 0.1 2.8 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit FAM110_C PF14160.6 EGC36067.1 - 0.023 15.8 0.2 0.18 12.9 0.0 2.5 2 0 0 2 2 2 0 Centrosome-associated C terminus Helicase_RecD PF05127.14 EGC36067.1 - 0.068 13.0 0.0 0.2 11.5 0.0 1.9 1 0 0 1 1 1 0 Helicase AAA_22 PF13401.6 EGC36067.1 - 1.2 9.4 4.1 1.8 8.8 1.4 2.7 2 1 0 2 2 2 0 AAA domain RasGAP PF00616.19 EGC36068.1 - 1.4e-12 47.8 15.1 1.9e-09 37.5 0.1 3.9 3 1 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.6 EGC36068.1 - 6.8e-10 38.2 40.2 0.0029 17.5 0.5 9.8 11 0 0 11 11 11 5 Leucine Rich repeat Carm_PH PF17888.1 EGC36068.1 - 0.002 18.4 0.6 0.022 15.1 0.1 2.9 2 0 0 2 2 2 1 Carmil pleckstrin homology domain LRR_1 PF00560.33 EGC36068.1 - 0.011 16.2 17.8 6.2 7.8 0.1 9.1 9 0 0 9 9 9 0 Leucine Rich Repeat PhoU PF01895.19 EGC36068.1 - 1.6 9.3 5.2 5 7.7 0.2 3.5 3 1 0 3 3 3 0 PhoU domain HMW1C_N PF18071.1 EGC36069.1 - 0.14 11.9 0.0 0.16 11.8 0.0 1.1 1 0 0 1 1 1 0 HMW1C N-terminal Vezatin PF12632.7 EGC36071.1 - 9.6e-08 31.7 20.8 9.6e-08 31.7 20.8 2.4 1 1 1 2 2 2 1 Mysoin-binding motif of peroxisomes DUF4709 PF15821.5 EGC36071.1 - 4.2 7.7 8.4 1.6 9.1 1.3 3.6 3 2 0 3 3 3 0 Domain of unknown function (DUF4709) Erg28 PF03694.13 EGC36072.1 - 5.2e-22 78.3 3.5 6.2e-22 78.1 3.5 1.1 1 0 0 1 1 1 1 Erg28 like protein BAR_3 PF16746.5 EGC36073.1 - 3.5e-67 226.6 21.4 3.5e-67 226.6 21.4 1.6 2 0 0 2 2 2 1 BAR domain of APPL family ArfGap PF01412.18 EGC36073.1 - 9e-39 132.2 0.0 9e-39 132.2 0.0 2.9 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.7 EGC36073.1 - 1.7e-14 54.1 0.8 2.8e-09 37.5 0.3 2.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) PH PF00169.29 EGC36073.1 - 1.8e-13 50.9 0.1 6e-13 49.2 0.1 2.0 1 0 0 1 1 1 1 PH domain Ank_4 PF13637.6 EGC36073.1 - 8.6e-09 35.8 0.4 0.00065 20.2 0.1 3.9 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC36073.1 - 3.7e-08 33.5 5.1 3.6e-06 27.2 0.1 3.7 2 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC36073.1 - 9.7e-07 29.0 1.5 0.91 10.1 0.1 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_3 PF13606.6 EGC36073.1 - 1.1e-06 28.4 1.2 0.45 11.2 0.1 4.7 4 0 0 4 4 4 2 Ankyrin repeat BAR PF03114.18 EGC36073.1 - 1.2e-06 28.3 11.9 1.6e-06 27.9 10.6 1.8 2 0 0 2 2 2 1 BAR domain PH_8 PF15409.6 EGC36073.1 - 0.00012 22.3 0.0 0.00042 20.5 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PX PF00787.24 EGC36074.1 - 8.4e-09 35.4 0.3 1e-08 35.1 0.3 1.1 1 0 0 1 1 1 1 PX domain Aldose_epim PF01263.20 EGC36075.1 - 8.3e-41 140.2 0.7 9.4e-41 140.1 0.7 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase DUF4432 PF14486.6 EGC36075.1 - 0.12 11.2 0.1 0.16 10.7 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4432) EF-hand_6 PF13405.6 EGC36076.1 - 1.4e-06 27.7 4.1 0.002 17.9 0.0 4.4 5 0 0 5 5 5 1 EF-hand domain EF-hand_1 PF00036.32 EGC36076.1 - 2.7e-05 23.4 0.3 0.052 13.1 0.0 3.8 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.6 EGC36076.1 - 0.0011 19.4 2.3 2.3 8.7 0.5 3.5 2 2 1 3 3 3 3 EF-hand domain pair DUF3637 PF12337.8 EGC36076.1 - 0.0099 16.2 0.1 2.8 8.3 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3637) ING PF12998.7 EGC36076.1 - 0.067 13.8 0.9 6.6 7.4 0.4 2.4 2 0 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding zf-C3HC4_2 PF13923.6 EGC36077.1 - 2.4e-11 43.3 9.0 4.3e-11 42.5 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36077.1 - 8.7e-10 38.8 8.8 1.5e-09 38.0 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC36077.1 - 1.6e-09 37.5 9.4 2.6e-09 36.8 9.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC36077.1 - 2.8e-08 33.5 12.0 5.7e-08 32.5 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC36077.1 - 4.5e-08 32.9 10.1 9.7e-08 31.9 10.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC36077.1 - 3.8e-06 26.8 5.1 2.4e-05 24.2 5.1 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC36077.1 - 6.4e-05 23.0 8.9 0.00016 21.7 8.5 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGC36077.1 - 0.00017 21.8 5.9 0.00017 21.8 5.9 2.2 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC36077.1 - 0.0006 19.6 8.6 0.002 17.9 8.6 1.9 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC36077.1 - 0.0011 18.6 6.2 0.0011 18.6 6.2 1.9 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 EGC36077.1 - 0.0034 17.5 6.8 0.0078 16.3 6.8 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC36077.1 - 0.009 15.8 8.6 0.022 14.5 8.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC36077.1 - 0.011 15.7 3.4 0.011 15.7 3.4 1.9 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger LapA_dom PF06305.11 EGC36077.1 - 1.2 9.0 0.0 1.2 9.0 0.0 4.3 4 1 0 4 4 2 0 Lipopolysaccharide assembly protein A domain DUF572 PF04502.13 EGC36077.1 - 3.4 7.2 34.6 2.5 7.7 6.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF572) V_ATPase_I PF01496.19 EGC36077.1 - 4.1 5.2 23.6 0.01 13.8 1.7 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FAM60A PF15396.6 EGC36077.1 - 4.6 7.2 22.2 2.8 7.9 6.5 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Methyltransf_10 PF05971.12 EGC36078.1 - 2.9e-29 102.4 3.3 5.7e-23 81.7 0.0 3.1 1 1 2 3 3 3 2 RNA methyltransferase MTS PF05175.14 EGC36078.1 - 3.5e-06 26.7 0.0 2.8e-05 23.7 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.13 EGC36078.1 - 1e-05 25.1 0.3 2.5e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.6 EGC36078.1 - 0.00056 19.7 2.0 0.0018 18.1 2.0 2.0 1 1 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.16 EGC36078.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein SAP30_Sin3_bdg PF13867.6 EGC36078.1 - 0.081 13.3 0.1 0.25 11.7 0.1 1.8 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Methyltransf_25 PF13649.6 EGC36078.1 - 0.2 12.4 0.0 0.52 11.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain DUF1700 PF08006.11 EGC36078.1 - 0.33 10.5 4.2 0.56 9.7 0.4 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Methyltransf_12 PF08242.12 EGC36078.1 - 0.38 11.5 0.0 0.38 11.5 0.0 2.6 3 1 0 3 3 3 0 Methyltransferase domain DsrD PF08679.11 EGC36078.1 - 0.66 10.3 3.8 2.3 8.5 0.4 3.2 3 0 0 3 3 3 0 Dissimilatory sulfite reductase D (DsrD) HEPN_AbiA_CTD PF18732.1 EGC36078.1 - 1.8 8.5 12.3 0.038 13.9 5.0 2.0 2 0 0 2 2 2 0 HEPN like, Abia C-terminal domain GDP_Man_Dehyd PF16363.5 EGC36079.1 - 1e-61 209.2 0.0 1.2e-61 209.0 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC36079.1 - 9.6e-55 185.7 0.0 1.2e-54 185.4 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC36079.1 - 1.5e-17 63.5 0.1 2.5e-16 59.5 0.0 2.0 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGC36079.1 - 1.7e-17 63.5 0.0 1.4e-16 60.5 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGC36079.1 - 3.2e-09 36.3 0.0 4.9e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGC36079.1 - 4e-09 36.6 0.0 7e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGC36079.1 - 1.9e-07 30.7 0.0 3.2e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGC36079.1 - 1e-06 28.8 0.0 1.6e-06 28.1 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC36079.1 - 5.2e-06 25.8 0.0 0.0011 18.2 0.0 2.5 1 1 1 2 2 2 2 Male sterility protein NmrA PF05368.13 EGC36079.1 - 0.084 12.4 0.1 0.24 10.9 0.0 1.8 2 1 0 2 2 2 0 NmrA-like family Sacchrp_dh_NADP PF03435.18 EGC36079.1 - 0.15 12.4 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain HHH_2 PF12826.7 EGC36079.1 - 0.18 12.0 1.2 8.4 6.6 0.0 2.7 2 1 1 3 3 2 0 Helix-hairpin-helix motif DapB_N PF01113.20 EGC36079.1 - 0.18 12.0 0.1 0.29 11.3 0.1 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.25 EGC36080.1 - 1.1e-42 145.7 0.1 1.4e-42 145.4 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36080.1 - 6.4e-24 84.8 0.0 8.1e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36080.1 - 2.4e-05 24.3 0.0 3.4e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC36080.1 - 0.0012 18.0 0.2 0.0037 16.4 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGC36080.1 - 0.013 15.0 0.3 0.064 12.7 0.3 1.9 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3236 PF11576.8 EGC36080.1 - 0.078 12.7 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Ibs_toxin PF13956.6 EGC36081.1 - 5.5 7.1 8.2 13 5.9 8.2 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Guanylate_cyc PF00211.20 EGC36082.1 - 1.8e-104 347.1 3.5 4.2e-52 176.4 0.5 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain Hira PF07569.11 EGC36084.1 - 6e-51 173.3 2.2 6e-51 173.3 2.2 2.1 2 0 0 2 2 2 1 TUP1-like enhancer of split WD40 PF00400.32 EGC36084.1 - 1.8e-28 98.2 26.0 3.4e-08 34.0 0.6 8.4 8 0 0 8 8 8 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36084.1 - 3.1e-12 46.6 5.4 0.022 15.1 0.1 6.5 3 1 4 7 7 7 4 Anaphase-promoting complex subunit 4 WD40 domain HIRA_B PF09453.10 EGC36084.1 - 4.4e-06 26.4 0.7 1.3e-05 25.0 0.7 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.12 EGC36084.1 - 9.5e-06 25.4 11.0 0.86 9.6 0.1 6.2 6 0 0 6 6 6 3 WD40-like Beta Propeller Repeat eIF2A PF08662.11 EGC36084.1 - 1.5e-05 25.0 0.1 0.11 12.4 0.2 3.4 2 2 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A Mcl1_mid PF12341.8 EGC36084.1 - 0.00014 21.4 0.8 0.00014 21.4 0.8 1.9 2 0 0 2 2 2 1 Minichromosome loss protein, Mcl1, middle region WD40_like PF17005.5 EGC36084.1 - 0.00015 21.2 0.7 0.72 9.1 0.0 3.8 3 1 0 4 4 4 2 WD40-like domain SelP_N PF04592.14 EGC36084.1 - 4.7 6.6 16.6 10 5.5 16.6 1.5 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Epimerase PF01370.21 EGC36085.1 - 1.6e-18 67.0 0.0 2.2e-18 66.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC36085.1 - 1.2e-13 50.7 0.3 7.4e-13 48.1 0.3 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.6 EGC36085.1 - 4.3e-12 46.3 0.1 7.5e-12 45.5 0.1 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGC36085.1 - 6.9e-12 45.1 0.1 9.7e-12 44.6 0.1 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGC36085.1 - 2e-08 34.1 0.0 2.6e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC36085.1 - 0.00031 20.0 0.3 0.00053 19.2 0.3 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGC36085.1 - 0.002 17.7 0.4 0.0031 17.1 0.4 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EGC36085.1 - 0.0031 16.7 0.9 0.2 10.8 0.9 2.5 1 1 0 1 1 1 1 Male sterility protein adh_short PF00106.25 EGC36085.1 - 0.004 16.6 0.2 0.0061 16.0 0.2 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EGC36085.1 - 0.0074 16.6 0.4 0.086 13.1 0.1 2.3 2 1 0 2 2 2 1 Saccharopine dehydrogenase NADP binding domain KR PF08659.10 EGC36085.1 - 0.014 15.3 0.0 0.027 14.4 0.0 1.4 1 1 0 1 1 1 0 KR domain DUF1731 PF08338.11 EGC36085.1 - 0.014 15.2 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PASTA PF03793.19 EGC36085.1 - 0.1 12.5 0.0 0.27 11.1 0.0 1.7 1 0 0 1 1 1 0 PASTA domain DDE_Tnp_4 PF13359.6 EGC36086.1 - 1.7e-15 57.0 0.1 3.3e-15 56.1 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PA14 PF07691.12 EGC36088.1 - 2.6e-13 50.0 0.1 4.5e-13 49.2 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC36088.1 - 6.7e-05 22.7 7.6 6.7e-05 22.7 7.6 13.4 13 2 1 14 14 14 7 Dictyostelium (slime mold) repeat DUF1640 PF07798.11 EGC36089.1 - 0.03 14.4 2.6 0.088 12.8 2.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) S6OS1 PF15676.5 EGC36089.1 - 0.18 10.2 11.3 0.3 9.5 11.3 1.4 1 1 0 1 1 1 0 Six6 opposite strand transcript 1 family Jnk-SapK_ap_N PF09744.9 EGC36089.1 - 0.3 11.3 4.6 0.28 11.4 1.7 1.9 2 0 0 2 2 2 0 JNK_SAPK-associated protein-1 bZIP_1 PF00170.21 EGC36089.1 - 1.9 8.6 8.2 2.6 8.2 1.4 2.9 1 1 1 2 2 2 0 bZIP transcription factor DUF2119 PF09892.9 EGC36090.1 - 0.0023 17.4 2.8 0.039 13.3 0.3 2.1 1 1 1 2 2 2 2 Uncharacterized protein conserved in archaea (DUF2119) HTH_52 PF18576.1 EGC36090.1 - 0.0044 17.2 1.3 0.92 9.8 0.1 2.2 2 0 0 2 2 2 2 Helix-turn-helix domain Ank_2 PF12796.7 EGC36090.1 - 0.018 15.7 0.6 0.1 13.2 0.6 1.9 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC36090.1 - 0.041 14.4 0.2 11 6.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat F-box-like_2 PF13013.6 EGC36090.1 - 0.12 12.3 0.9 0.37 10.8 0.9 1.8 1 1 0 1 1 1 0 F-box-like domain Pdase_M17_N2 PF18295.1 EGC36090.1 - 0.18 12.0 0.0 15 5.9 0.0 2.1 2 0 0 2 2 2 0 M17 aminopeptidase N-terminal domain 2 UBA_2 PF08587.11 EGC36090.1 - 0.19 11.9 4.7 2.9 8.1 0.1 2.5 2 1 0 2 2 2 0 Ubiquitin associated domain (UBA) RPAP1_C PF08620.10 EGC36091.1 - 2.3e-20 72.4 0.1 9.3e-20 70.5 0.0 2.2 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.10 EGC36091.1 - 2.1e-08 33.8 3.1 7e-08 32.1 3.1 2.0 1 0 0 1 1 1 1 RPAP1-like, N-terminal UQ_con PF00179.26 EGC36092.1 - 4.8e-45 152.7 0.4 5.7e-44 149.2 0.2 2.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 EGC36092.1 - 2.8e-10 40.8 0.0 9.2e-10 39.1 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 EGC36092.1 - 9.5e-07 28.6 0.2 5.8e-06 26.1 0.1 2.4 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC36092.1 - 5.3e-06 26.1 0.1 1.5e-05 24.6 0.1 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_5 PF18037.1 EGC36092.1 - 0.00051 20.3 0.1 0.0012 19.2 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain Prok-E2_B PF14461.6 EGC36092.1 - 0.032 14.0 0.0 0.061 13.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family B RBD PF02196.15 EGC36092.1 - 0.044 13.9 0.0 0.099 12.7 0.0 1.6 1 0 0 1 1 1 0 Raf-like Ras-binding domain RasGEF PF00617.19 EGC36093.1 - 8.7e-59 198.7 10.3 3.4e-58 196.7 4.8 2.8 3 0 0 3 3 3 2 RasGEF domain RasGEF_N PF00618.20 EGC36093.1 - 3.6e-18 65.7 0.9 3.6e-18 65.7 0.9 2.9 3 1 0 3 3 3 1 RasGEF N-terminal motif DEP PF00610.21 EGC36093.1 - 0.019 15.0 0.0 0.061 13.4 0.0 1.9 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Inhibitor_I69 PF13734.6 EGC36093.1 - 0.058 13.8 1.6 0.12 12.8 0.5 2.1 2 0 0 2 2 2 0 Spi protease inhibitor Kelch_1 PF01344.25 EGC36094.1 - 5.8e-21 73.8 0.1 1.1e-09 37.7 0.1 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.6 EGC36094.1 - 3.2e-19 68.6 0.2 7.1e-07 29.1 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC36094.1 - 1.2e-15 57.1 1.8 6.1e-05 23.2 0.3 3.2 2 1 1 3 3 3 3 Kelch motif Kelch_3 PF13415.6 EGC36094.1 - 5.2e-15 55.3 0.2 2.7e-05 24.4 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC36094.1 - 7.7e-11 41.5 0.0 0.0013 18.6 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.6 EGC36094.1 - 6.7e-07 29.2 0.6 0.00025 21.0 0.0 3.2 3 0 0 3 3 3 1 Kelch motif RWP-RK PF02042.15 EGC36095.1 - 4.8e-23 80.9 0.1 4.8e-23 80.9 0.1 1.7 2 0 0 2 2 2 1 RWP-RK domain HlyIII PF03006.20 EGC36096.1 - 1.6e-58 198.0 14.0 2.6e-58 197.4 14.0 1.3 1 0 0 1 1 1 1 Haemolysin-III related PAP2_C PF14360.6 EGC36096.1 - 8.6 7.0 16.0 0.52 10.9 1.5 3.8 3 0 0 3 3 3 0 PAP2 superfamily C-terminal Barstar PF01337.18 EGC36097.1 - 8.5e-06 25.7 0.4 3.3e-05 23.8 0.4 1.9 1 1 0 1 1 1 1 Barstar (barnase inhibitor) Cystatin PF00031.21 EGC36099.1 - 6.2e-06 26.4 0.0 6.6e-06 26.3 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.21 EGC36100.1 - 3.7e-08 33.5 1.5 4.4e-08 33.3 1.5 1.2 1 0 0 1 1 1 1 Cystatin domain SQAPI PF16845.5 EGC36100.1 - 0.02 15.2 0.7 0.023 15.1 0.7 1.2 1 0 0 1 1 1 0 Aspartic acid proteinase inhibitor EABR PF12180.8 EGC36100.1 - 0.098 12.3 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 ABC_membrane PF00664.23 EGC36101.1 - 3.9e-68 230.1 38.2 5.9e-40 137.7 9.6 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC36101.1 - 2.2e-49 167.5 0.3 1.5e-27 96.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter MTABC_N PF16185.5 EGC36101.1 - 2.2e-10 40.5 5.1 6.3e-10 39.0 5.1 1.8 1 0 0 1 1 1 1 Mitochondrial ABC-transporter N-terminal five TM region SMC_N PF02463.19 EGC36101.1 - 7.9e-09 35.3 5.9 0.024 14.1 0.1 4.3 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGC36101.1 - 2.5e-08 34.0 1.0 0.029 14.5 0.0 4.0 4 0 0 4 4 4 2 50S ribosome-binding GTPase AAA_29 PF13555.6 EGC36101.1 - 6.7e-05 22.6 0.2 0.46 10.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC36101.1 - 0.00036 20.9 0.0 0.88 9.9 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain RsgA_GTPase PF03193.16 EGC36101.1 - 0.00051 20.0 1.5 0.37 10.7 0.6 2.7 2 1 0 2 2 2 2 RsgA GTPase Dynamin_N PF00350.23 EGC36101.1 - 0.00059 19.9 0.5 0.22 11.6 0.2 3.2 3 0 0 3 3 2 1 Dynamin family AAA_23 PF13476.6 EGC36101.1 - 0.00076 20.0 8.5 3.1 8.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain GTP_EFTU PF00009.27 EGC36101.1 - 0.0072 15.9 0.1 0.9 9.0 0.0 2.4 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGC36101.1 - 0.011 16.0 1.2 4.8 7.4 0.2 2.7 3 0 0 3 3 2 0 AAA domain NB-ARC PF00931.22 EGC36101.1 - 0.016 14.4 0.6 4.7 6.3 0.1 2.5 2 0 0 2 2 2 0 NB-ARC domain MeaB PF03308.16 EGC36101.1 - 0.028 13.4 0.6 2.5 7.0 0.1 2.2 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_21 PF13304.6 EGC36101.1 - 0.031 14.1 1.7 0.9 9.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EGC36101.1 - 0.038 14.2 0.4 11 6.2 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase FKBP_N_2 PF18023.1 EGC36101.1 - 0.068 13.3 0.3 0.19 11.8 0.3 1.7 1 0 0 1 1 1 0 BDBT FKBP like N-terminal AAA_7 PF12775.7 EGC36101.1 - 0.097 12.2 0.4 10 5.6 0.1 2.3 2 0 0 2 2 2 0 P-loop containing dynein motor region Zeta_toxin PF06414.12 EGC36101.1 - 0.1 11.9 0.8 9.4 5.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin DUF4258 PF14076.6 EGC36101.1 - 0.11 12.9 0.2 12 6.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) CDC45 PF02724.14 EGC36101.1 - 0.3 9.3 4.8 0.46 8.7 4.8 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF87 PF01935.17 EGC36101.1 - 3.4 7.7 10.4 0.72 9.9 0.1 2.9 3 0 0 3 3 3 0 Helicase HerA, central domain F_actin_bind PF08919.10 EGC36102.1 - 7e-07 29.3 1.5 1e-06 28.8 1.5 1.2 1 0 0 1 1 1 1 F-actin binding Vinculin PF01044.19 EGC36102.1 - 5.1e-05 21.7 1.4 6.2e-05 21.4 1.4 1.1 1 0 0 1 1 1 1 Vinculin family NPA PF16469.5 EGC36102.1 - 0.0052 17.3 3.4 0.021 15.4 2.1 2.2 2 1 0 2 2 2 1 Nematode polyprotein allergen ABA-1 GCIP PF13324.6 EGC36102.1 - 0.031 13.9 6.2 0.017 14.8 3.8 1.7 1 1 1 2 2 2 0 Grap2 and cyclin-D-interacting Rrp44_S1 PF17215.3 EGC36102.1 - 0.28 11.2 2.3 0.24 11.4 0.5 1.7 2 0 0 2 2 2 0 S1 domain 60KD_IMP PF02096.20 EGC36103.1 - 1.5e-18 67.3 0.8 2.4e-18 66.6 0.8 1.2 1 0 0 1 1 1 1 60Kd inner membrane protein DUF4064 PF13273.6 EGC36104.1 - 0.48 10.7 14.5 0.045 14.0 1.9 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) OppC_N PF12911.7 EGC36104.1 - 1.1 9.3 12.7 3.4 7.7 0.0 4.2 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ABC2_membrane_2 PF12679.7 EGC36104.1 - 1.3 8.3 9.9 5.8 6.1 0.4 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF4131 PF13567.6 EGC36104.1 - 3.3 7.3 8.7 1.1 8.8 1.6 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) CSG2 PF16965.5 EGC36105.1 - 0.0034 16.4 3.3 0.0034 16.4 3.3 1.6 1 1 1 2 2 2 1 Ceramide synthase regulator CLN3 PF02487.17 EGC36105.1 - 0.0041 16.2 0.5 0.0067 15.5 0.5 1.3 1 0 0 1 1 1 1 CLN3 protein Menin PF05053.13 EGC36105.1 - 0.013 13.9 8.7 0.018 13.5 8.7 1.1 1 0 0 1 1 1 0 Menin DUF4834 PF16118.5 EGC36105.1 - 0.021 15.8 5.0 0.021 15.8 5.0 3.8 4 1 0 4 4 4 0 Domain of unknown function (DUF4834) Zip PF02535.22 EGC36105.1 - 0.022 14.0 0.1 0.053 12.7 0.0 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter HCO3_cotransp PF00955.21 EGC36105.1 - 0.12 11.1 5.9 0.2 10.5 5.9 1.3 1 0 0 1 1 1 0 HCO3- transporter family Tim54 PF11711.8 EGC36105.1 - 1.5 7.5 5.9 2.4 6.8 5.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Podoplanin PF05808.11 EGC36105.1 - 6.6 6.8 5.6 83 3.2 0.0 2.1 2 0 0 2 2 2 0 Podoplanin Presenilin PF01080.17 EGC36105.1 - 6.7 5.4 13.8 2.3 6.9 10.4 1.8 1 1 1 2 2 2 0 Presenilin DUF2076 PF09849.9 EGC36105.1 - 7.2 6.6 10.7 11 6.0 10.7 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) SCIMP PF15050.6 EGC36106.1 - 0.046 14.2 0.3 11 6.5 0.0 2.8 2 0 0 2 2 2 0 SCIMP protein Gal4_dimer PF03902.13 EGC36106.1 - 0.22 11.7 0.4 1.3 9.3 0.0 2.3 2 0 0 2 2 2 0 Gal4-like dimerisation domain Connexin PF00029.19 EGC36107.1 - 0.17 11.6 0.1 0.17 11.6 0.1 2.6 2 1 0 2 2 2 0 Connexin RIFIN PF02009.16 EGC36107.1 - 3.1 7.6 15.4 1.8 8.4 8.8 2.2 2 0 0 2 2 2 0 Rifin DUF4149 PF13664.6 EGC36108.1 - 0.21 11.9 12.4 1.9 8.8 0.6 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4149) YL1 PF05764.13 EGC36109.1 - 0.008 16.3 12.0 0.008 16.3 12.0 2.5 3 0 0 3 3 3 1 YL1 nuclear protein FNIP PF05725.12 EGC36110.1 - 1.2e-63 211.0 38.5 5.8e-16 58.4 4.6 5.1 4 1 1 5 5 5 5 FNIP Repeat LRR_5 PF13306.6 EGC36110.1 - 0.55 10.2 3.3 4.5 7.3 1.1 2.8 1 1 1 2 2 2 0 BspA type Leucine rich repeat region (6 copies) LRR_1 PF00560.33 EGC36110.1 - 6.1 7.8 16.4 8.3 7.4 0.2 5.8 1 1 2 3 3 3 0 Leucine Rich Repeat MAPKK1_Int PF08923.10 EGC36111.1 - 3.4e-35 120.4 5.5 4e-35 120.2 5.5 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Erf4 PF10256.9 EGC36112.1 - 4.4e-07 30.0 6.7 2.8e-06 27.4 0.0 2.3 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family LapA_dom PF06305.11 EGC36112.1 - 0.00017 21.3 1.4 0.44 10.4 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide assembly protein A domain TetR_C_2 PF08361.11 EGC36112.1 - 0.11 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 MAATS-type transcriptional repressor, C-terminal region Herpes_UL73 PF03554.13 EGC36112.1 - 2.4 8.2 7.3 0.32 11.0 1.1 2.6 3 0 0 3 3 3 0 UL73 viral envelope glycoprotein Secretin_N_2 PF07655.13 EGC36113.1 - 0.21 12.1 9.4 1.3 9.6 1.8 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain HD PF01966.22 EGC36114.1 - 3.9e-10 40.0 0.1 7.7e-10 39.1 0.1 1.4 1 0 0 1 1 1 1 HD domain Methyltransf_16 PF10294.9 EGC36115.1 - 2e-23 83.0 1.4 1.2e-22 80.5 1.4 1.9 1 1 0 1 1 1 1 Lysine methyltransferase GidB PF02527.15 EGC36115.1 - 3.1e-06 26.6 0.3 6.2e-06 25.7 0.3 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G MTS PF05175.14 EGC36115.1 - 3.8e-05 23.3 0.0 6.5e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGC36115.1 - 0.00065 20.4 0.0 0.0014 19.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36115.1 - 0.00065 19.5 0.1 0.0013 18.5 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain TRM PF02005.16 EGC36115.1 - 0.00066 18.9 0.0 0.00096 18.4 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PCMT PF01135.19 EGC36115.1 - 0.0045 16.7 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGC36115.1 - 0.0076 15.7 0.5 0.017 14.5 0.5 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.12 EGC36115.1 - 0.022 15.5 0.1 0.054 14.2 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36115.1 - 0.041 13.7 0.0 0.063 13.1 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.16 EGC36115.1 - 0.046 13.5 0.6 0.068 12.9 0.7 1.3 1 1 0 1 1 1 0 Met-10+ like-protein Methyltransf_11 PF08241.12 EGC36115.1 - 0.067 13.8 0.0 0.13 12.9 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain BBS2_Mid PF14783.6 EGC36118.1 - 0.00015 21.7 0.7 0.0036 17.3 0.0 3.4 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.23 EGC36118.1 - 0.18 11.9 0.0 0.36 11.0 0.0 1.4 1 0 0 1 1 1 0 FG-GAP repeat ABC2_membrane_2 PF12679.7 EGC36118.1 - 0.23 10.7 1.2 0.41 9.9 1.2 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein TERB2 PF15101.6 EGC36118.1 - 0.32 11.0 15.3 1.3 9.0 15.3 2.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Pox_Ag35 PF03286.14 EGC36118.1 - 0.6 9.9 15.1 0.013 15.3 6.3 2.5 2 0 0 2 2 2 0 Pox virus Ag35 surface protein CobT PF06213.12 EGC36118.1 - 0.84 9.0 17.7 0.026 13.9 10.6 1.9 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT FliP PF00813.20 EGC36118.1 - 1.2 9.0 3.8 3.1 7.6 3.8 1.7 1 0 0 1 1 1 0 FliP family PepSY_TM PF03929.16 EGC36118.1 - 1.8 8.1 4.0 3.8 7.1 4.0 1.5 1 0 0 1 1 1 0 PepSY-associated TM region Serinc PF03348.15 EGC36118.1 - 1.9 7.3 4.5 3.8 6.3 4.5 1.5 1 0 0 1 1 1 0 Serine incorporator (Serinc) SprA-related PF12118.8 EGC36118.1 - 2.6 7.1 28.1 8.2 5.5 28.1 1.8 1 0 0 1 1 1 0 SprA-related family Kei1 PF08552.11 EGC36118.1 - 2.6 7.9 5.0 6.6 6.6 5.0 1.7 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 RskA PF10099.9 EGC36118.1 - 5 7.4 13.3 14 5.9 13.4 1.5 1 1 0 1 1 1 0 Anti-sigma-K factor rskA DUF853 PF05872.12 EGC36118.1 - 6.7 5.2 9.6 16 3.9 8.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) WD40 PF00400.32 EGC36119.1 - 9.1e-16 58.0 11.3 0.0087 16.9 0.0 6.9 6 0 0 6 6 6 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36119.1 - 7.9e-09 35.7 0.2 0.32 11.3 0.0 4.8 3 1 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGC36119.1 - 0.00028 20.9 0.1 1.7 8.7 0.0 4.4 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region DUF3911 PF13050.6 EGC36119.1 - 3.9 7.7 11.2 0.031 14.4 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) Cullin PF00888.22 EGC36121.1 - 3.6e-215 716.3 19.9 5.3e-215 715.7 19.9 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGC36121.1 - 1.4e-27 95.5 3.2 1.4e-27 95.5 3.2 2.3 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.11 EGC36121.1 - 0.021 14.8 0.3 0.22 11.5 0.1 2.6 1 1 1 2 2 2 0 HbrB-like dCache_1 PF02743.18 EGC36121.1 - 0.052 13.3 0.3 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Cache domain Penicillinase_R PF03965.16 EGC36121.1 - 0.057 13.8 2.5 0.42 11.0 0.3 3.2 3 0 0 3 3 3 0 Penicillinase repressor WAC_Acf1_DNA_bd PF10537.9 EGC36121.1 - 0.065 13.8 2.3 0.14 12.7 0.6 2.5 2 0 0 2 2 2 0 ATP-utilising chromatin assembly and remodelling N-terminal Clat_adaptor_s PF01217.20 EGC36122.1 - 2.7e-38 131.1 4.5 3.1e-38 130.9 4.5 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CwfJ_C_1 PF04677.15 EGC36123.1 - 1.9e-31 108.5 0.3 5.9e-31 106.9 0.3 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.14 EGC36123.1 - 4.2e-08 34.0 0.0 4.2e-08 34.0 0.0 2.8 2 1 1 3 3 3 1 Protein similar to CwfJ C-terminus 2 GAGA_bind PF06217.12 EGC36123.1 - 4.2 7.6 13.6 0.99 9.6 9.6 1.9 3 0 0 3 3 3 0 GAGA binding protein-like family KTI12 PF08433.10 EGC36124.1 - 1.5e-96 323.0 0.2 1.7e-96 322.8 0.2 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.6 EGC36124.1 - 3.4e-10 40.2 0.0 1.2e-09 38.5 0.0 1.9 2 1 0 2 2 2 1 AAA domain APS_kinase PF01583.20 EGC36124.1 - 0.027 14.4 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.17 EGC36124.1 - 0.13 11.9 0.2 0.53 9.9 0.1 2.4 2 1 0 2 2 2 0 Thymidylate kinase MeaB PF03308.16 EGC36124.1 - 0.19 10.7 0.0 0.37 9.7 0.0 1.4 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB zf-TRAF PF02176.18 EGC36125.1 - 5.1e-09 36.7 11.1 5.1e-09 36.7 11.1 2.2 1 1 2 3 3 3 1 TRAF-type zinc finger ATG16 PF08614.11 EGC36125.1 - 0.0018 18.6 2.6 0.0023 18.2 2.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) XhlA PF10779.9 EGC36125.1 - 0.0085 16.3 1.6 0.017 15.3 1.6 1.5 1 0 0 1 1 1 1 Haemolysin XhlA zf_UBZ PF18439.1 EGC36125.1 - 0.13 11.8 5.3 3.7 7.2 0.1 3.0 2 1 1 3 3 3 0 Ubiquitin-Binding Zinc Finger LPD11 PF18824.1 EGC36125.1 - 0.74 9.9 5.4 0.44 10.7 2.3 2.2 2 1 0 2 2 2 0 Large polyvalent protein-associated domain 11 Cyto_heme_lyase PF01265.17 EGC36125.1 - 1.5 8.3 8.0 1.8 8.0 8.0 1.1 1 0 0 1 1 1 0 Cytochrome c/c1 heme lyase VAPB_antitox PF02697.14 EGC36125.1 - 8.2 7.3 15.6 0.24 12.2 2.2 3.2 2 1 1 3 3 3 0 Putative antitoxin zf-C2HC5 PF06221.13 EGC36125.1 - 8.9 6.4 11.3 5.1 7.2 0.4 2.7 3 0 0 3 3 3 0 Putative zinc finger motif, C2HC5-type YhhN PF07947.14 EGC36126.1 - 6.4e-43 146.5 21.8 1.1e-42 145.7 21.8 1.4 1 0 0 1 1 1 1 YhhN family Glyco_hydro_36N PF16875.5 EGC36128.1 - 0.039 13.5 0.0 0.057 13.0 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 36 N-terminal domain PDCD2_C PF04194.13 EGC36129.1 - 1.4e-31 110.0 7.5 4.2e-31 108.3 1.2 2.7 2 2 0 2 2 2 2 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.18 EGC36129.1 - 1.5e-07 31.4 16.5 1.5e-07 31.4 16.5 3.5 3 1 0 3 3 3 1 MYND finger CENP-B_dimeris PF09026.10 EGC36129.1 - 0.24 11.8 7.4 0.51 10.8 7.4 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Rap_GAP PF02145.15 EGC36130.1 - 4.6e-61 205.6 0.0 6.2e-61 205.2 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Ank_5 PF13857.6 EGC36131.1 - 5.6e-17 61.6 0.6 2e-10 40.7 0.1 3.2 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC36131.1 - 9e-15 54.4 0.4 1.1e-09 38.3 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat Ank_2 PF12796.7 EGC36131.1 - 4.1e-13 49.7 0.1 8.4e-13 48.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36131.1 - 6.6e-13 48.9 0.1 5e-08 33.3 0.0 2.7 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC36131.1 - 2e-11 43.0 0.4 1.5e-05 25.0 0.0 3.6 3 0 0 3 3 3 2 Ankyrin repeat RA PF00788.23 EGC36131.1 - 2.4e-09 37.7 0.0 6e-09 36.4 0.0 1.6 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain XFP_N PF09364.10 EGC36131.1 - 0.027 13.3 0.0 0.041 12.7 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain FliD_C PF07195.12 EGC36131.1 - 0.048 13.1 2.1 0.097 12.1 2.1 1.5 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus ATP-synt_E PF05680.12 EGC36131.1 - 0.096 13.0 3.1 0.18 12.1 3.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain PPV_E1_N PF00524.18 EGC36131.1 - 0.12 12.8 2.4 0.25 11.8 2.3 1.5 1 1 0 1 1 1 0 E1 Protein, N terminal domain LAMTOR5 PF16672.5 EGC36132.1 - 4.3e-25 87.5 0.3 4.7e-25 87.3 0.3 1.0 1 0 0 1 1 1 1 Ragulator complex protein LAMTOR5 Robl_LC7 PF03259.17 EGC36132.1 - 0.009 15.8 0.0 0.041 13.7 0.0 1.8 1 1 0 1 1 1 1 Roadblock/LC7 domain RhoGEF PF00621.20 EGC36134.1 - 2.9e-43 148.2 5.7 2.9e-43 148.2 5.7 3.0 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.31 EGC36134.1 - 9.4e-37 125.5 1.3 1.5e-18 67.0 1.5 2.9 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC36134.1 - 6e-05 22.8 0.1 0.029 14.2 0.0 3.0 2 0 0 2 2 2 1 CAMSAP CH domain IQ PF00612.27 EGC36134.1 - 0.00038 20.0 2.0 0.00093 18.8 2.0 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif CCDC53 PF10152.9 EGC36134.1 - 0.011 16.2 9.9 0.011 16.2 9.9 3.1 2 0 0 2 2 2 0 Subunit CCDC53 of WASH complex PH_10 PF15411.6 EGC36134.1 - 0.042 14.1 0.6 0.042 14.1 0.6 3.0 2 0 0 2 2 2 0 Pleckstrin homology domain RuvB_C PF05491.13 EGC36134.1 - 0.082 12.8 0.0 8.4 6.4 0.0 2.9 2 0 0 2 2 2 0 RuvB C-terminal winged helix domain PH PF00169.29 EGC36134.1 - 1.6 9.3 6.4 0.28 11.7 0.8 2.6 2 0 0 2 2 2 0 PH domain TFIIA PF03153.13 EGC36134.1 - 1.7 8.5 29.3 3.7 7.4 29.3 1.5 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF948 PF06103.11 EGC36134.1 - 3.4 8.0 10.8 25 5.2 2.7 3.9 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BTB_2 PF02214.22 EGC36135.1 - 1.3e-16 60.7 0.0 1.1e-15 57.7 0.0 2.4 3 0 0 3 3 3 1 BTB/POZ domain Ead_Ea22 PF13935.6 EGC36135.1 - 0.0094 16.6 0.3 0.018 15.7 0.3 1.4 1 0 0 1 1 1 1 Ead/Ea22-like protein DUF4482 PF14818.6 EGC36135.1 - 0.025 15.5 0.6 0.042 14.7 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DegQ PF08181.11 EGC36135.1 - 0.031 14.4 0.4 0.074 13.2 0.4 1.6 1 0 0 1 1 1 0 DegQ (SacQ) family BTB_3 PF16017.5 EGC36135.1 - 0.06 13.5 0.0 0.26 11.4 0.0 2.0 2 0 0 2 2 2 0 BTB/POZ domain Mcm10 PF09332.11 EGC36135.1 - 0.31 10.4 5.6 0.45 9.9 5.6 1.1 1 0 0 1 1 1 0 Mcm10 replication factor SKA1 PF07160.12 EGC36135.1 - 0.32 10.8 8.3 0.66 9.8 8.3 1.5 1 1 0 1 1 1 0 Spindle and kinetochore-associated protein 1 ALMT PF11744.8 EGC36135.1 - 0.36 9.6 7.7 0.49 9.2 7.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Macoilin PF09726.9 EGC36135.1 - 2.4 6.6 13.0 2.7 6.4 13.0 1.1 1 0 0 1 1 1 0 Macoilin family Kelch_1 PF01344.25 EGC36136.1 - 3.7e-30 103.3 14.0 7.1e-15 54.3 0.2 6.0 6 1 0 6 6 6 3 Kelch motif Kelch_6 PF13964.6 EGC36136.1 - 2.3e-28 97.5 6.3 1.2e-09 38.1 0.2 4.8 3 2 2 5 5 5 3 Kelch motif Kelch_4 PF13418.6 EGC36136.1 - 2e-15 56.5 2.9 5.8e-05 23.0 0.1 4.3 3 1 1 4 4 4 3 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC36136.1 - 3.1e-15 55.4 5.7 6.6e-07 29.1 0.0 5.1 5 2 0 5 5 5 3 Kelch motif Kelch_5 PF13854.6 EGC36136.1 - 1e-11 44.5 2.2 3.5e-05 23.7 0.1 4.4 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGC36136.1 - 7.6e-08 32.5 3.1 0.0047 17.2 0.1 3.7 3 1 1 4 4 4 3 Galactose oxidase, central domain PQQ_3 PF13570.6 EGC36136.1 - 0.0015 19.0 0.1 9.6 6.9 0.1 3.5 3 0 0 3 3 3 1 PQQ-like domain FBA_1 PF07734.13 EGC36136.1 - 0.069 13.1 0.0 0.41 10.5 0.0 2.1 2 1 1 3 3 3 0 F-box associated PglD_N PF17836.1 EGC36137.1 - 0.068 13.8 0.2 0.15 12.7 0.2 1.6 1 0 0 1 1 1 0 PglD N-terminal domain PH PF00169.29 EGC36138.1 - 1.1e-05 25.9 6.2 0.00057 20.4 0.1 3.3 4 0 0 4 4 4 2 PH domain PARP PF00644.20 EGC36139.1 - 5.3e-13 49.0 7.0 7.8e-12 45.2 2.2 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain ARID PF01388.21 EGC36140.1 - 0.00017 22.2 0.6 0.00065 20.3 0.6 2.1 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain DUF2046 PF09755.9 EGC36141.1 - 5.2e-25 88.3 44.9 8.5e-23 81.0 31.7 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) PH PF00169.29 EGC36141.1 - 0.0003 21.3 2.5 0.00047 20.6 0.0 2.6 2 1 1 3 3 3 1 PH domain MetW PF07021.12 EGC36141.1 - 0.05 13.2 4.8 0.54 9.8 3.3 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW MAD PF05557.13 EGC36141.1 - 3.4 5.9 43.9 1.9 6.8 20.8 2.1 1 1 1 2 2 2 0 Mitotic checkpoint protein HpcH_HpaI PF03328.14 EGC36142.1 - 3.9e-42 143.9 0.2 1.9e-41 141.6 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.6 EGC36142.1 - 2.4e-17 63.1 0.3 1.3e-10 41.0 0.0 2.2 1 1 1 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold CBM49 PF09478.10 EGC36143.1 - 3.1e-15 56.2 0.8 4.1e-15 55.8 0.8 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 WD40 PF00400.32 EGC36144.1 - 0.014 16.3 9.2 2.2 9.3 0.2 4.2 4 0 0 4 4 4 0 WD domain, G-beta repeat Rav1p_C PF12234.8 EGC36145.1 - 2e-99 333.8 0.0 2e-99 333.8 0.0 3.0 3 0 0 3 3 3 1 RAVE protein 1 C terminal WD40 PF00400.32 EGC36145.1 - 5.2e-19 68.2 21.0 0.018 15.9 0.0 11.1 10 0 0 10 10 10 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36145.1 - 2.1e-06 27.9 0.7 0.85 10.0 0.0 6.1 6 2 1 7 7 7 3 Anaphase-promoting complex subunit 4 WD40 domain GRP PF07172.11 EGC36145.1 - 1.7 9.4 5.1 5.7 7.7 5.1 1.9 1 0 0 1 1 1 0 Glycine rich protein family tRNA-synt_1 PF00133.22 EGC36146.1 - 1.2e-19 70.0 0.0 1.3e-11 43.5 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC36146.1 - 7.3e-12 45.5 5.0 9.3e-12 45.2 2.6 2.5 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA Chorein_N PF12624.7 EGC36147.1 - 6e-22 78.0 5.6 5.2e-21 74.9 1.8 3.2 1 1 1 2 2 2 1 N-terminal region of Chorein or VPS13 Med15 PF09606.10 EGC36147.1 - 1.3 7.6 9.9 2 7.0 9.9 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal CH PF00307.31 EGC36149.1 - 2.1e-42 143.7 11.7 2.1e-17 63.3 0.2 5.0 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC36149.1 - 7.5e-06 25.7 1.2 0.00014 21.6 0.1 3.3 3 0 0 3 3 3 1 CAMSAP CH domain CH_2 PF06294.11 EGC36149.1 - 0.00075 19.6 3.3 0.093 12.9 0.1 4.9 4 0 0 4 4 4 1 CH-like domain in sperm protein RecG_N PF17190.4 EGC36149.1 - 0.015 16.0 8.7 0.015 16.0 8.7 10.3 4 1 3 10 10 10 0 RecG N-terminal helical domain HAP1_N PF04849.13 EGC36150.1 - 5.5e-05 22.5 43.3 0.0065 15.7 41.0 3.8 2 1 0 2 2 2 1 HAP1 N-terminal conserved region KASH_CCD PF14662.6 EGC36150.1 - 0.00055 19.8 47.7 0.0014 18.5 20.2 2.6 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 or KASH Alkyl_sulf_dimr PF14863.6 EGC36150.1 - 0.00077 19.9 1.2 0.0024 18.3 1.2 1.8 1 0 0 1 1 1 1 Alkyl sulfatase dimerisation BAR_3 PF16746.5 EGC36150.1 - 0.0011 18.7 7.1 0.0011 18.7 7.1 3.2 4 0 0 4 4 4 2 BAR domain of APPL family YojJ PF10372.9 EGC36150.1 - 0.017 15.2 1.0 0.017 15.2 1.0 3.3 4 1 0 4 4 4 0 Bacterial membrane-spanning protein N-terminus DivIC PF04977.15 EGC36150.1 - 0.1 12.4 32.0 0.14 12.0 2.9 5.3 3 1 1 4 4 4 0 Septum formation initiator bZIP_1 PF00170.21 EGC36150.1 - 0.51 10.5 38.3 0.16 12.1 2.7 5.2 3 1 1 4 4 4 0 bZIP transcription factor SOGA PF11365.8 EGC36150.1 - 7.3 7.8 30.4 0.49 11.6 1.7 4.1 3 1 0 3 3 3 0 Protein SOGA TSC22 PF01166.18 EGC36150.1 - 8.4 6.8 27.8 6.1 7.2 0.8 5.4 3 1 1 4 4 4 0 TSC-22/dip/bun family Las1 PF04031.13 EGC36151.1 - 3.9e-39 134.2 0.2 6.3e-38 130.3 0.0 2.3 2 0 0 2 2 2 1 Las1-like F-actin_cap_A PF01267.17 EGC36153.1 - 7.2e-85 284.6 0.3 8.1e-85 284.5 0.3 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit F_actin_cap_B PF01115.17 EGC36153.1 - 0.014 15.1 0.4 0.023 14.3 0.2 1.4 1 1 0 1 1 1 0 F-actin capping protein, beta subunit DUF1768 PF08719.11 EGC36154.1 - 1.1e-36 126.6 0.5 1.2e-36 126.4 0.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Mad3_BUB1_I_2 PF17014.5 EGC36154.1 - 0.088 12.9 1.4 0.15 12.2 1.2 1.7 1 1 0 1 1 1 0 Putative Mad3/BUB1 like region 1 protein Trp_halogenase PF04820.14 EGC36155.1 - 5.5e-14 51.9 0.0 1.2e-08 34.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.24 EGC36155.1 - 0.00025 20.7 0.0 0.0035 17.0 0.0 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGC36155.1 - 0.025 13.8 0.0 0.072 12.3 0.0 1.7 2 0 0 2 2 2 0 Thi4 family Curto_V2 PF07325.11 EGC36155.1 - 0.084 12.7 0.1 8 6.4 0.0 2.6 2 0 0 2 2 2 0 Curtovirus V2 protein DUF4144 PF13642.6 EGC36155.1 - 0.092 13.3 0.1 0.58 10.8 0.0 2.2 2 0 0 2 2 2 0 protein structure with unknown function NAD_binding_9 PF13454.6 EGC36155.1 - 0.095 12.7 0.0 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EGC36155.1 - 0.2 10.9 0.0 0.64 9.2 0.0 1.8 1 1 0 1 1 1 0 FAD binding domain Ribosomal_60s PF00428.19 EGC36156.1 - 0.00091 19.8 4.6 0.003 18.1 4.6 1.9 1 0 0 1 1 1 1 60s Acidic ribosomal protein TRH PF05438.12 EGC36156.1 - 0.0047 16.7 3.5 0.046 13.5 0.5 2.3 2 0 0 2 2 2 1 Thyrotropin-releasing hormone (TRH) GnsAB_toxin PF08178.11 EGC36156.1 - 0.096 12.6 2.8 4.7 7.2 0.0 2.7 2 0 0 2 2 2 0 GnsA/GnsB toxin of bacterial toxin-antitoxin system Nop16 PF09420.10 EGC36156.1 - 0.16 12.0 0.0 0.16 12.0 0.0 2.5 3 0 0 3 3 3 0 Ribosome biogenesis protein Nop16 Catalase-rel PF06628.12 EGC36156.1 - 0.16 12.2 0.4 0.7 10.1 0.0 2.3 2 0 0 2 2 2 0 Catalase-related immune-responsive Pox_Ag35 PF03286.14 EGC36156.1 - 0.26 11.0 11.5 0.24 11.2 10.0 1.7 1 1 0 1 1 1 0 Pox virus Ag35 surface protein DUF1631 PF07793.11 EGC36156.1 - 0.49 8.8 5.7 0.026 13.0 0.3 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1631) Sa_NUDIX PF18167.1 EGC36156.1 - 1.1 9.0 6.1 0.4 10.5 2.7 1.8 2 0 0 2 2 2 0 SMODS-associated NUDIX domain Itfg2 PF15907.5 EGC36156.1 - 2.2 7.2 8.2 12 4.9 5.5 2.3 1 1 1 2 2 2 0 Integrin-alpha FG-GAP repeat-containing protein 2 NOA36 PF06524.12 EGC36156.1 - 2.7 7.2 9.5 0.33 10.2 5.3 1.6 2 0 0 2 2 2 0 NOA36 protein G10 PF01125.17 EGC36157.1 - 1.1e-61 206.9 6.9 1.2e-61 206.7 6.9 1.0 1 0 0 1 1 1 1 G10 protein Catalase PF00199.19 EGC36159.1 - 2.3e-172 573.4 0.3 3.6e-172 572.8 0.0 1.4 2 0 0 2 2 2 1 Catalase Catalase-rel PF06628.12 EGC36159.1 - 1.5e-19 69.9 0.1 3.5e-19 68.8 0.1 1.7 1 0 0 1 1 1 1 Catalase-related immune-responsive Catalase_C PF18011.1 EGC36159.1 - 8.2e-13 48.3 0.0 1.3e-12 47.6 0.0 1.3 1 0 0 1 1 1 1 C-terminal domain found in long catalases DJ-1_PfpI PF01965.24 EGC36159.1 - 0.0015 18.4 0.0 0.0025 17.6 0.0 1.3 1 0 0 1 1 1 1 DJ-1/PfpI family PH PF00169.29 EGC36160.1 - 6.2e-13 49.2 0.3 1.5e-12 47.9 0.3 1.7 1 0 0 1 1 1 1 PH domain EAF PF09816.9 EGC36161.1 - 2.3e-13 50.4 0.4 2.7e-13 50.2 0.4 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor PhoPQ_related PF10142.9 EGC36163.1 - 1.3e-117 392.5 6.4 1.6e-117 392.2 6.4 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Pkinase PF00069.25 EGC36164.1 - 5.7e-38 130.8 0.0 5.7e-38 130.8 0.0 3.4 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36164.1 - 2.7e-26 92.4 0.0 1e-25 90.5 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGC36164.1 - 2.3e-10 40.7 10.5 2.3e-10 40.7 10.5 3.9 2 1 0 2 2 2 1 Ribonuclease 2-5A Kinase-like PF14531.6 EGC36164.1 - 0.00014 21.3 0.0 0.00023 20.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC36164.1 - 0.062 12.6 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NDUFB11 PF17250.2 EGC36166.1 - 0.099 13.3 0.2 2.3 8.9 0.0 2.5 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase 11 kDa subunit Mating_N PF12731.7 EGC36166.1 - 0.11 12.6 0.5 0.48 10.5 0.1 2.1 2 0 0 2 2 2 0 Mating-type protein beta 1 Dimer_Tnp_hAT PF05699.14 EGC36167.1 - 4.3e-13 48.9 0.2 5.3e-13 48.6 0.2 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nup35_RRM PF05172.13 EGC36168.1 - 1.2e-10 41.2 0.1 2.6e-10 40.1 0.1 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGC36168.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_1 PF00076.22 EGC36168.1 - 0.0054 16.5 0.0 0.007 16.2 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-lactamase PF00144.24 EGC36169.1 - 3.1e-50 171.3 0.0 4.8e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase DUF2806 PF10987.8 EGC36172.1 - 0.019 14.9 0.2 0.019 14.9 0.2 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2806) Vps16_C PF04840.12 EGC36173.1 - 4.3e-85 285.6 7.2 7.3e-85 284.8 7.2 1.3 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.13 EGC36173.1 - 5.7e-80 269.1 0.1 9.1e-80 268.4 0.1 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region DUF4131 PF13567.6 EGC36174.1 - 0.16 11.7 6.9 0.29 10.8 6.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Methyltransf_PK PF05891.12 EGC36175.1 - 4.4e-73 245.4 0.1 5.6e-73 245.1 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGC36175.1 - 3e-08 34.3 0.0 6.9e-08 33.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36175.1 - 2.7e-05 24.8 0.0 5.4e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36175.1 - 3.7e-05 23.6 0.0 7.9e-05 22.6 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36175.1 - 4.5e-05 24.0 0.0 0.0001 22.8 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_2 PF00891.18 EGC36175.1 - 0.027 13.7 0.2 0.075 12.3 0.2 1.7 1 1 0 1 1 1 0 O-methyltransferase domain RrnaAD PF00398.20 EGC36175.1 - 0.038 13.1 0.0 0.049 12.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase RT_RNaseH_2 PF17919.1 EGC36177.1 - 2.3e-13 50.0 0.0 2.4e-13 50.0 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH PF17917.1 EGC36177.1 - 6.7e-13 48.8 0.0 7.1e-13 48.7 0.0 1.0 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase DEAD PF00270.29 EGC36178.1 - 6.5e-34 117.2 1.1 1.5e-33 116.1 1.1 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC36178.1 - 1.1e-32 112.6 0.1 2.1e-29 102.1 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.6 EGC36178.1 - 1.5e-13 50.4 7.0 1.5e-13 50.4 7.0 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC36178.1 - 1.3e-05 25.0 8.2 1.3e-05 25.0 8.2 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC36178.1 - 0.0055 17.0 8.3 0.0055 17.0 8.3 2.6 2 0 0 2 2 2 1 Ring finger domain ResIII PF04851.15 EGC36178.1 - 0.011 15.8 7.6 0.011 15.8 7.6 4.4 3 2 1 4 4 4 0 Type III restriction enzyme, res subunit Bombinin PF05298.11 EGC36178.1 - 0.033 13.9 0.3 0.089 12.5 0.3 1.7 1 0 0 1 1 1 0 Bombinin zf-C3HC4_2 PF13923.6 EGC36178.1 - 0.21 11.5 7.7 0.67 9.8 7.7 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Serinc PF03348.15 EGC36178.1 - 6.8 5.5 10.9 0.39 9.6 0.5 2.5 2 0 0 2 2 2 0 Serine incorporator (Serinc) zf-RING_UBOX PF13445.6 EGC36178.1 - 6.9 6.8 7.7 5.7 7.0 2.3 2.9 2 0 0 2 2 2 0 RING-type zinc-finger WD40 PF00400.32 EGC36179.1 - 1.3e-05 25.8 0.6 0.00046 20.9 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36179.1 - 0.0004 20.6 0.2 0.0012 19.1 0.2 1.8 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC36179.1 - 0.0014 17.3 0.1 0.0028 16.4 0.1 1.5 1 0 0 1 1 1 1 Nucleoporin Nup120/160 Clat_adaptor_s PF01217.20 EGC36180.1 - 2.5e-08 34.0 2.1 2.9e-08 33.8 2.1 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RXT2_N PF08595.11 EGC36180.1 - 0.039 14.0 0.1 0.1 12.6 0.0 1.7 2 0 0 2 2 2 0 RXT2-like, N-terminal RepB-RCR_reg PF10723.9 EGC36180.1 - 0.048 13.6 0.0 0.1 12.5 0.0 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB Chromo PF00385.24 EGC36181.1 - 1.4e-09 37.7 3.6 1.6e-09 37.5 3.6 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OTU PF02338.19 EGC36182.1 - 4.3e-10 40.2 0.2 1.9e-09 38.1 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease TFIIA PF03153.13 EGC36182.1 - 0.031 14.3 16.5 0.043 13.8 16.5 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGC36182.1 - 0.052 12.3 12.1 0.08 11.6 12.1 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Zip PF02535.22 EGC36182.1 - 3 7.0 7.3 5.2 6.2 6.0 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter Ank_2 PF12796.7 EGC36183.1 - 1.7e-26 92.6 9.8 3.4e-14 53.2 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36183.1 - 1.7e-18 66.7 0.4 2.3e-10 40.8 0.1 3.7 2 1 1 3 3 3 3 Ankyrin repeats (many copies) CH PF00307.31 EGC36183.1 - 1.8e-17 63.5 0.8 5.9e-17 61.8 0.8 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain Ank_3 PF13606.6 EGC36183.1 - 1.2e-16 59.1 0.4 0.00087 19.6 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.6 EGC36183.1 - 7.5e-16 58.0 4.8 3.2e-07 30.5 0.1 3.8 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC36183.1 - 7.4e-13 48.3 0.8 0.0015 18.9 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat DUF3292 PF11696.8 EGC36183.1 - 0.012 14.1 0.3 0.018 13.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) CDC24 PF06395.11 EGC36183.1 - 0.016 15.5 0.2 0.045 14.0 0.2 1.8 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 EGC36183.1 - 0.043 13.6 0.0 0.091 12.6 0.0 1.5 1 0 0 1 1 1 0 CAMSAP CH domain PPL5 PF18168.1 EGC36183.1 - 0.87 8.8 4.8 1.4 8.2 4.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 AAA_23 PF13476.6 EGC36183.1 - 1.3 9.5 13.3 0.46 10.9 9.3 2.2 2 0 0 2 2 2 0 AAA domain SPX PF03105.19 EGC36183.1 - 1.9 8.4 18.0 2.9 7.7 18.0 1.2 1 0 0 1 1 1 0 SPX domain Casc1_N PF15927.5 EGC36183.1 - 6 6.5 27.8 19 4.8 27.8 1.9 1 1 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus DOMON PF03351.17 EGC36184.1 - 1.4e-21 77.0 0.3 1.4e-21 77.0 0.3 2.3 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.16 EGC36184.1 - 3e-14 53.3 11.1 3e-14 53.3 11.1 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 Halogen_Hydrol PF10112.9 EGC36184.1 - 0.59 10.1 8.6 0.21 11.6 0.8 2.3 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein OAD_gamma PF04277.13 EGC36184.1 - 0.78 10.4 3.6 0.98 10.1 0.0 2.7 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF4079 PF13301.6 EGC36184.1 - 8.3 6.6 11.0 21 5.2 7.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4079) DUF4209 PF13910.6 EGC36186.1 - 4.7e-28 97.3 2.1 2.3e-23 82.2 0.1 3.3 3 0 0 3 3 3 2 Domain of unknown function (DUF4209) NUC153 PF08159.12 EGC36187.1 - 1.1e-07 31.5 0.4 4.4e-07 29.6 0.3 2.1 2 0 0 2 2 2 1 NUC153 domain ANAPC4_WD40 PF12894.7 EGC36187.1 - 0.092 13.1 0.0 22 5.4 0.0 3.5 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AAA PF00004.29 EGC36188.1 - 3.5e-43 147.2 0.0 8.7e-43 145.9 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC36188.1 - 3.8e-13 49.0 0.1 7.6e-13 48.0 0.1 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGC36188.1 - 1.9e-07 31.3 0.0 5.3e-07 29.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGC36188.1 - 6.9e-06 26.1 0.0 2.8e-05 24.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC36188.1 - 8.3e-06 26.3 0.0 0.00013 22.4 0.0 2.4 2 1 0 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC36188.1 - 3.5e-05 24.1 0.3 0.0072 16.6 0.3 2.5 1 1 0 1 1 1 1 AAA domain Prot_ATP_ID_OB PF16450.5 EGC36188.1 - 7.9e-05 22.5 0.5 0.0002 21.3 0.5 1.7 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain RuvB_N PF05496.12 EGC36188.1 - 8.1e-05 22.4 0.0 0.00015 21.6 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGC36188.1 - 0.0013 18.1 0.0 0.0024 17.1 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_33 PF13671.6 EGC36188.1 - 0.0015 18.7 0.0 0.0029 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.17 EGC36188.1 - 0.0029 17.4 0.0 0.0056 16.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.6 EGC36188.1 - 0.003 18.1 0.7 0.022 15.3 0.0 2.4 3 0 0 3 3 2 1 AAA domain AAA_3 PF07726.11 EGC36188.1 - 0.0032 17.3 0.0 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase PF01078.21 EGC36188.1 - 0.0083 15.5 0.1 0.018 14.4 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_28 PF13521.6 EGC36188.1 - 0.012 15.8 0.0 0.024 14.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.16 EGC36188.1 - 0.013 15.0 0.0 0.15 11.5 0.0 2.2 2 0 0 2 2 2 0 PhoH-like protein ATPase PF06745.13 EGC36188.1 - 0.014 14.8 0.0 0.036 13.4 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_24 PF13479.6 EGC36188.1 - 0.014 15.1 0.0 0.096 12.4 0.0 2.1 2 0 0 2 2 2 0 AAA domain TsaE PF02367.17 EGC36188.1 - 0.016 15.2 0.0 0.031 14.3 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE RNA_helicase PF00910.22 EGC36188.1 - 0.02 15.3 0.0 0.043 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_7 PF12775.7 EGC36188.1 - 0.029 13.9 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGC36188.1 - 0.038 13.7 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.13 EGC36188.1 - 0.04 13.1 0.0 0.087 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.17 EGC36188.1 - 0.047 12.8 0.0 0.082 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_25 PF13481.6 EGC36188.1 - 0.048 13.2 0.1 0.16 11.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGC36188.1 - 0.056 13.9 0.1 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.6 EGC36188.1 - 0.058 13.4 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.9 EGC36188.1 - 0.063 12.5 0.7 1.6 7.9 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) APG6_N PF17675.1 EGC36188.1 - 0.073 13.6 1.3 0.17 12.4 1.3 1.5 1 0 0 1 1 1 0 Apg6 coiled-coil region AAA_19 PF13245.6 EGC36188.1 - 0.092 13.1 0.1 0.67 10.3 0.1 2.3 3 0 0 3 3 2 0 AAA domain ABC_tran PF00005.27 EGC36188.1 - 0.1 13.1 0.4 0.73 10.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter FlaC_arch PF05377.11 EGC36188.1 - 0.12 12.8 4.2 0.26 11.7 1.6 2.6 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) DASH_Dad2 PF08654.10 EGC36188.1 - 0.22 12.0 1.7 0.44 11.0 0.6 2.1 3 0 0 3 3 1 0 DASH complex subunit Dad2 AAA_11 PF13086.6 EGC36188.1 - 0.24 11.1 2.2 0.35 10.6 0.1 2.2 2 1 0 2 2 2 0 AAA domain zf-U1 PF06220.12 EGC36189.1 - 4.6e-21 74.3 4.7 6.4e-21 73.8 4.7 1.2 1 0 0 1 1 1 1 U1 zinc finger DUF5470 PF17564.2 EGC36189.1 - 0.016 15.4 0.5 0.094 12.9 0.0 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5470) Birna_VP3 PF01767.16 EGC36189.1 - 0.061 13.4 0.0 0.061 13.4 0.0 1.0 1 0 0 1 1 1 0 Birnavirus VP3 protein zf-met PF12874.7 EGC36189.1 - 0.21 12.0 4.9 4.3 7.9 4.9 2.2 1 1 0 1 1 1 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC36189.1 - 0.35 11.2 11.1 5.6 7.4 11.1 2.2 1 1 0 1 1 1 0 Zinc-finger double-stranded RNA-binding Peptidase_S49 PF01343.18 EGC36190.1 - 5.5e-63 211.5 1.2 5.3e-39 133.6 0.0 2.7 3 0 0 3 3 3 2 Peptidase family S49 SDH_sah PF01972.16 EGC36190.1 - 9.8e-05 21.5 0.0 0.00018 20.6 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.23 EGC36190.1 - 0.0024 17.8 1.3 0.48 10.3 0.6 2.6 2 0 0 2 2 2 2 Clp protease THF_DHG_CYH PF00763.23 EGC36190.1 - 0.083 13.2 0.4 3.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ntox46 PF15538.6 EGC36190.1 - 0.093 12.7 0.1 15 5.5 0.0 2.3 2 0 0 2 2 2 0 Bacterial toxin 46 Ligase_CoA PF00549.19 EGC36190.1 - 0.1 12.4 0.1 0.34 10.7 0.0 1.9 2 0 0 2 2 2 0 CoA-ligase GAD PF02938.14 EGC36190.1 - 0.19 12.0 1.3 1.5 9.1 0.1 3.0 4 0 0 4 4 4 0 GAD domain Flavoprotein PF02441.19 EGC36191.1 - 8.9e-51 171.8 0.2 1e-50 171.5 0.2 1.1 1 0 0 1 1 1 1 Flavoprotein CspB_prodomain PF18425.1 EGC36191.1 - 9.4e-05 22.3 1.1 0.00017 21.5 1.1 1.4 1 0 0 1 1 1 1 Csp protease B prodomain TPR_12 PF13424.6 EGC36192.1 - 7.4e-12 45.4 0.5 9.2e-08 32.3 0.0 2.5 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGC36192.1 - 2.4e-05 24.1 0.0 0.0025 17.6 0.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.9 EGC36192.1 - 0.0006 19.6 1.9 0.00098 18.9 1.9 1.3 1 1 0 1 1 1 1 26S proteasome subunit RPN7 SNAP PF14938.6 EGC36192.1 - 0.025 14.0 0.2 0.035 13.5 0.2 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP TPR_7 PF13176.6 EGC36192.1 - 0.036 14.1 0.0 0.22 11.6 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF2225 PF09986.9 EGC36192.1 - 0.038 13.7 0.5 0.059 13.1 0.5 1.3 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) TPR_19 PF14559.6 EGC36192.1 - 0.056 14.0 0.6 2.3 8.8 0.1 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC36192.1 - 0.067 13.4 2.5 2.6 8.5 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF4296 PF14129.6 EGC36192.1 - 0.087 13.4 3.5 6.9 7.4 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4296) TPR_1 PF00515.28 EGC36192.1 - 0.13 12.1 0.6 0.86 9.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat KOW PF00467.29 EGC36193.1 - 2e-24 84.7 21.8 3.9e-07 29.8 0.4 7.3 7 0 0 7 7 7 6 KOW motif Spt5-NGN PF03439.13 EGC36193.1 - 7.1e-18 64.3 0.0 1.4e-17 63.4 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.8 EGC36193.1 - 0.0034 18.3 24.6 0.0034 18.3 24.6 3.4 3 0 0 3 3 3 1 Spt5 transcription elongation factor, acidic N-terminal DUF3912 PF13051.6 EGC36193.1 - 0.0095 16.2 3.9 0.89 9.9 0.0 4.6 6 0 0 6 6 6 1 Protein of unknown function (DUF3912) PCB_OB PF17092.5 EGC36193.1 - 0.024 15.4 0.3 0.17 12.7 0.0 2.6 3 0 0 3 3 3 0 Penicillin-binding protein OB-like domain PCNA_N PF00705.18 EGC36194.1 - 2.4e-50 169.5 1.9 3.7e-50 168.9 1.3 1.6 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.15 EGC36194.1 - 7e-46 155.5 0.3 3.4e-45 153.3 0.1 2.0 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad9 PF04139.13 EGC36194.1 - 0.00065 19.2 0.2 0.00075 19.0 0.2 1.1 1 0 0 1 1 1 1 Rad9 DUF1854 PF08909.11 EGC36194.1 - 0.015 15.1 0.1 0.79 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1854) SprA-related PF12118.8 EGC36194.1 - 0.19 10.9 0.5 0.27 10.3 0.5 1.2 1 0 0 1 1 1 0 SprA-related family Ribosomal_L35p PF01632.19 EGC36195.1 - 0.0056 17.1 0.3 0.01 16.3 0.3 1.5 1 0 0 1 1 1 1 Ribosomal protein L35 EF-hand_7 PF13499.6 EGC36196.1 - 1.9e-09 37.9 4.7 1.3e-08 35.2 0.6 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC36196.1 - 4.7e-07 29.2 4.4 0.00096 18.9 0.1 3.4 3 0 0 3 3 3 3 EF-hand domain EF_assoc_1 PF08355.12 EGC36196.1 - 1.8e-05 24.2 0.0 2.7e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 EF hand associated EF-hand_1 PF00036.32 EGC36196.1 - 0.0015 18.0 0.1 0.0015 18.0 0.1 3.1 3 1 1 4 4 4 2 EF hand EF-hand_5 PF13202.6 EGC36196.1 - 8.3 6.1 7.9 22 4.8 0.0 3.5 3 1 0 3 3 3 0 EF hand FNIP PF05725.12 EGC36198.1 - 7.5e-154 499.7 82.2 3.1e-16 59.2 0.8 12.2 5 2 9 15 15 15 15 FNIP Repeat CN_hydrolase PF00795.22 EGC36199.1 - 3.2e-66 223.3 0.0 3.8e-66 223.1 0.0 1.0 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Erf4 PF10256.9 EGC36201.1 - 2.1e-05 24.6 1.0 0.00035 20.7 1.0 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ATP-synt_I PF03899.15 EGC36201.1 - 0.0045 17.3 0.6 0.0064 16.8 0.6 1.1 1 0 0 1 1 1 1 ATP synthase I chain YibE_F PF07907.11 EGC36201.1 - 0.0075 15.8 0.7 0.01 15.4 0.7 1.1 1 0 0 1 1 1 1 YibE/F-like protein GAPES4 PF17157.4 EGC36201.1 - 0.013 15.9 0.3 0.032 14.6 0.2 1.7 1 1 1 2 2 2 0 Gammaproteobacterial periplasmic sensor domain Peptidase_M50B PF13398.6 EGC36201.1 - 0.037 13.7 0.6 0.049 13.3 0.6 1.1 1 0 0 1 1 1 0 Peptidase M50B-like Interfer-bind PF09294.10 EGC36201.1 - 0.14 12.5 2.4 0.28 11.5 2.3 1.6 1 1 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF3267 PF11667.8 EGC36202.1 - 0.003 17.8 1.8 0.0062 16.8 1.8 1.5 1 0 0 1 1 1 1 Putative zincin peptidase FA_desaturase PF00487.24 EGC36202.1 - 0.026 14.4 0.1 0.047 13.5 0.1 1.4 1 1 0 1 1 1 0 Fatty acid desaturase DUF2207 PF09972.9 EGC36203.1 - 0.79 8.4 13.4 0.027 13.2 6.3 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) FA_FANCE PF11510.8 EGC36204.1 - 4.8e-11 42.5 1.8 8.2e-11 41.7 1.8 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Asp-B-Hydro_N PF05279.11 EGC36204.1 - 0.22 11.6 7.4 0.16 12.1 0.7 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region RRM_1 PF00076.22 EGC36205.1 - 1.5e-39 133.7 1.1 1.4e-15 56.9 0.0 4.6 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OB_RNB PF08206.11 EGC36205.1 - 0.073 12.8 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain RR_TM4-6 PF06459.12 EGC36205.1 - 5.5 6.7 31.9 0.073 12.9 24.1 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 TPR_8 PF13181.6 EGC36206.1 - 7.6e-17 60.1 4.2 0.02 15.1 0.0 8.9 10 0 0 10 10 10 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC36206.1 - 4.1e-15 54.6 0.0 0.072 13.2 0.0 8.1 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC36206.1 - 2.9e-14 52.2 0.2 0.0032 17.2 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC36206.1 - 1.9e-12 47.5 0.3 0.0013 19.2 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGC36206.1 - 2.4e-12 46.5 0.0 0.39 11.6 0.0 7.2 5 1 2 7 7 7 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGC36206.1 - 9.2e-10 38.7 0.0 1.1 9.6 0.0 6.6 3 1 5 8 8 8 4 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC36206.1 - 3.3e-05 24.0 1.3 0.18 12.1 0.0 4.5 3 1 3 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.6 EGC36206.1 - 0.0004 20.0 0.0 3.3 7.5 0.0 4.4 4 0 0 4 4 4 2 TPR repeat TPR_9 PF13371.6 EGC36206.1 - 0.0018 18.4 0.0 2.2 8.5 0.0 3.3 2 2 1 3 3 3 1 Tetratricopeptide repeat Glutaredoxin PF00462.24 EGC36206.1 - 0.01 16.0 0.0 0.47 10.7 0.0 2.8 2 0 0 2 2 2 0 Glutaredoxin TPR_MalT PF17874.1 EGC36206.1 - 0.032 13.6 3.1 2.1 7.7 0.2 2.8 1 1 2 3 3 3 0 MalT-like TPR region HrpB1_HrpK PF09613.10 EGC36206.1 - 0.04 13.6 0.1 0.2 11.3 0.1 2.2 2 1 0 2 2 2 0 Bacterial type III secretion protein (HrpB1_HrpK) CENP-B_dimeris PF09026.10 EGC36206.1 - 2.2 8.7 7.8 4.9 7.6 7.8 1.6 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Kri1_C PF12936.7 EGC36207.1 - 5.1e-18 65.0 4.4 5.1e-18 65.0 4.4 5.1 4 2 1 5 5 5 1 KRI1-like family C-terminal Es2 PF09751.9 EGC36208.1 - 5.6e-76 257.0 17.0 5.6e-76 257.0 17.0 2.2 1 1 1 2 2 2 1 Nuclear protein Es2 Peptidase_C1 PF00112.23 EGC36209.1 - 5.9e-50 170.4 6.0 7.1e-50 170.1 6.0 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.15 EGC36209.1 - 0.64 8.7 2.8 0.81 8.4 0.6 1.9 2 0 0 2 2 2 0 Peptidase C1-like family Ribosomal_L6e PF01159.19 EGC36210.1 - 6e-39 133.0 4.8 6e-39 133.0 4.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L6e 4HBT PF03061.22 EGC36211.1 - 3.7e-10 40.0 0.0 5.4e-07 29.9 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.22 EGC36211.1 - 0.00026 20.8 0.1 0.00088 19.0 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Profilin PF00235.19 EGC36212.1 - 2.9e-47 160.1 2.5 3.2e-47 159.9 2.5 1.0 1 0 0 1 1 1 1 Profilin TIG PF01833.24 EGC36213.1 - 8.3e-06 25.8 16.4 0.0052 16.8 1.8 3.9 3 0 0 3 3 3 2 IPT/TIG domain SKG6 PF08693.10 EGC36213.1 - 0.0054 16.1 6.1 0.012 15.0 6.1 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_1 PF00560.33 EGC36213.1 - 0.02 15.4 4.8 12 6.9 0.6 5.5 2 1 0 2 2 2 0 Leucine Rich Repeat LRR_4 PF12799.7 EGC36213.1 - 0.048 14.1 0.1 0.048 14.1 0.1 5.1 5 1 0 5 5 5 0 Leucine Rich repeats (2 copies) DUF3827 PF12877.7 EGC36213.1 - 0.056 11.8 0.3 0.078 11.3 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) Laminin_EGF PF00053.24 EGC36213.1 - 0.12 12.5 6.1 0.37 11.0 6.1 1.8 1 0 0 1 1 1 0 Laminin EGF domain LRR_8 PF13855.6 EGC36213.1 - 0.12 12.1 11.2 0.067 13.0 4.1 3.9 3 1 2 5 5 5 0 Leucine rich repeat LRR_6 PF13516.6 EGC36213.1 - 0.21 11.7 5.0 18 5.7 0.2 3.7 3 0 0 3 3 3 0 Leucine Rich repeat EGF_alliinase PF04863.13 EGC36213.1 - 3.8 8.0 6.1 0.69 10.4 1.8 2.0 2 0 0 2 2 2 0 Alliinase EGF-like domain EGF_2 PF07974.13 EGC36213.1 - 9 6.8 27.8 0.051 14.0 10.4 3.0 3 0 0 3 3 3 0 EGF-like domain Ank_2 PF12796.7 EGC36214.1 - 2.5e-40 136.9 1.4 3.1e-10 40.5 0.3 4.9 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36214.1 - 2.8e-33 113.8 7.0 2.4e-05 24.8 0.0 7.7 4 2 3 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC36214.1 - 2.6e-30 104.1 1.8 7.9e-05 22.9 0.0 7.0 6 1 1 7 7 7 6 Ankyrin repeats (many copies) Ank PF00023.30 EGC36214.1 - 2.6e-29 100.4 8.6 4.8e-06 26.8 0.4 8.9 8 0 0 8 8 8 7 Ankyrin repeat Ank_3 PF13606.6 EGC36214.1 - 1.7e-21 74.0 4.8 0.016 15.7 0.0 8.8 8 0 0 8 8 8 5 Ankyrin repeat BTB PF00651.31 EGC36214.1 - 2.1e-18 66.5 0.0 6.8e-05 23.1 0.0 4.9 4 0 0 4 4 4 4 BTB/POZ domain FNIP PF05725.12 EGC36215.1 - 2.2e-139 453.4 61.1 5.4e-16 58.5 0.3 9.9 3 1 7 12 12 12 12 FNIP Repeat MCM_OB PF17207.3 EGC36215.1 - 0.0051 16.7 0.4 1.8e+02 2.0 0.0 5.6 3 2 7 10 10 10 0 MCM OB domain Peptidase_C21 PF05381.12 EGC36215.1 - 0.11 12.8 5.9 15 6.0 0.1 4.4 2 2 2 4 4 4 0 Tymovirus endopeptidase LRR_1 PF00560.33 EGC36215.1 - 4.6 8.2 21.9 52 5.0 0.5 8.3 6 2 0 7 7 7 0 Leucine Rich Repeat Strumpellin PF10266.9 EGC36216.1 - 0 1514.9 26.4 0 1514.7 26.4 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin Lip_prot_lig_C PF10437.9 EGC36217.1 - 3.6e-20 71.7 1.0 5.4e-19 68.0 0.4 2.6 2 0 0 2 2 2 1 Bacterial lipoate protein ligase C-terminus BPL_LplA_LipB PF03099.19 EGC36217.1 - 2.7e-07 30.6 0.0 6.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family PRTP PF01366.18 EGC36217.1 - 0.065 11.3 0.2 0.1 10.6 0.2 1.2 1 0 0 1 1 1 0 Herpesvirus processing and transport protein ADK PF00406.22 EGC36218.1 - 3.1e-51 173.4 0.0 3.7e-51 173.2 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_17 PF13207.6 EGC36218.1 - 7.8e-40 136.4 0.0 9.9e-40 136.1 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC36218.1 - 3.7e-13 50.1 0.0 5.3e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGC36218.1 - 1.2e-07 32.0 0.0 2e-07 31.2 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGC36218.1 - 8.7e-06 25.1 0.0 1.2e-05 24.7 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.17 EGC36218.1 - 0.0013 18.5 0.3 0.83 9.3 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.29 EGC36218.1 - 0.0069 16.8 0.2 0.022 15.2 0.0 1.7 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.19 EGC36218.1 - 0.0086 15.9 1.2 0.011 15.7 0.2 1.6 2 0 0 2 2 2 1 Deoxynucleoside kinase Ploopntkinase3 PF18751.1 EGC36218.1 - 0.043 13.7 0.0 0.066 13.1 0.0 1.3 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 AAA_19 PF13245.6 EGC36218.1 - 0.048 14.0 0.0 0.092 13.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-CCHC_3 PF13917.6 EGC36219.1 - 7.4e-16 57.8 1.6 1.6e-15 56.7 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle CD34_antigen PF06365.12 EGC36220.1 - 0.023 14.3 0.1 0.068 12.7 0.0 2.0 2 1 0 2 2 2 0 CD34/Podocalyxin family GATA PF00320.27 EGC36221.1 - 8.2e-08 31.7 3.8 2.2e-07 30.3 3.8 1.7 1 1 0 1 1 1 1 GATA zinc finger GATA PF00320.27 EGC36222.1 - 0.013 15.1 5.7 0.024 14.2 5.7 1.4 1 0 0 1 1 1 0 GATA zinc finger DZR PF12773.7 EGC36225.1 - 0.00073 19.5 0.3 0.54 10.3 0.0 2.1 2 0 0 2 2 2 2 Double zinc ribbon Pkinase PF00069.25 EGC36226.1 - 5.4e-29 101.4 2.6 9.7e-29 100.5 1.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36226.1 - 8.2e-23 81.0 0.1 1.6e-20 73.5 0.1 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.22 EGC36226.1 - 4.3e-05 23.2 0.8 8.3e-05 22.3 0.2 1.9 2 0 0 2 2 2 1 RIO1 family Pkinase_fungal PF17667.1 EGC36226.1 - 0.00027 19.9 0.1 0.00029 19.8 0.1 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC36226.1 - 0.0012 18.3 0.0 0.0019 17.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC36226.1 - 0.0072 16.3 0.1 0.39 10.6 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family LXG PF04740.12 EGC36226.1 - 0.035 13.8 0.8 0.065 12.9 0.8 1.3 1 0 0 1 1 1 0 LXG domain of WXG superfamily tRNA-synt_2c PF01411.19 EGC36227.1 - 1.3e-52 179.1 0.5 4.2e-43 147.7 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class II (A) Homeodomain PF00046.29 EGC36228.1 - 7.6e-13 48.1 0.2 6.3e-08 32.4 0.0 2.7 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC36228.1 - 5e-05 23.1 0.1 0.0038 17.1 0.1 3.0 1 1 0 1 1 1 1 Homeobox KN domain Mucin PF01456.17 EGC36228.1 - 4.8 7.2 37.5 0.8 9.7 32.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein HMG_box PF00505.19 EGC36232.1 - 4.9e-18 65.3 3.1 9.9e-18 64.3 3.1 1.6 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.10 EGC36232.1 - 4.9e-13 49.5 2.3 4.9e-13 49.5 2.3 1.9 1 1 1 2 2 2 1 HMG-box domain YABBY PF04690.13 EGC36232.1 - 1.5 9.4 5.8 0.23 12.0 1.3 1.7 1 1 1 2 2 2 0 YABBY protein RICTOR_M PF14666.6 EGC36233.1 - 0.0082 15.9 0.8 0.062 13.1 0.1 2.8 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, middle domain Tti2 PF10521.9 EGC36233.1 - 0.11 12.1 0.1 0.11 12.1 0.1 2.4 2 0 0 2 2 2 0 Tti2 family zf-CpG_bind_C PF12269.8 EGC36234.1 - 0.0041 16.9 0.3 0.0043 16.9 0.3 1.1 1 0 0 1 1 1 1 CpG binding protein zinc finger C terminal domain zf-H2C2_5 PF13909.6 EGC36234.1 - 0.0079 15.9 0.6 0.019 14.7 0.6 1.7 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2 PF00096.26 EGC36234.1 - 0.058 13.9 1.4 0.14 12.7 1.4 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type CHIP_TPR_N PF18391.1 EGC36235.1 - 0.81 10.5 7.2 1.4 9.8 6.7 1.6 1 1 0 1 1 1 0 CHIP N-terminal tetratricopeptide repeat domain FtsH_ext PF06480.15 EGC36235.1 - 4.1 7.8 12.4 11 6.4 12.4 1.6 1 1 0 1 1 1 0 FtsH Extracellular Cys_Met_Meta_PP PF01053.20 EGC36236.1 - 3.5e-25 88.4 0.3 4.4e-25 88.0 0.3 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGC36236.1 - 1.1e-06 28.0 0.1 1.6e-06 27.5 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2738 PF10927.8 EGC36236.1 - 0.0014 17.8 0.2 0.0024 17.0 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2738) Lamp PF01299.17 EGC36237.1 - 0.1 12.4 8.0 0.2 11.5 8.0 1.4 1 1 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) TbpB_C PF17483.2 EGC36237.1 - 0.28 11.6 4.5 0.32 11.4 2.6 1.8 1 1 1 2 2 2 0 C-lobe handle domain of Tf-binding protein B GATA PF00320.27 EGC36238.1 - 0.24 11.0 11.3 0.088 12.4 8.6 1.7 2 0 0 2 2 2 0 GATA zinc finger Peptidase_C4 PF00863.19 EGC36239.1 - 0.12 11.6 0.4 0.17 11.2 0.2 1.4 2 0 0 2 2 2 0 Peptidase family C4 Nitr_red_alph_N PF14710.6 EGC36240.1 - 1.7 9.2 5.3 27 5.3 0.3 2.9 3 0 0 3 3 3 0 Respiratory nitrate reductase alpha N-terminal GAGA_bind PF06217.12 EGC36240.1 - 2.4 8.3 24.6 2.8 8.2 24.6 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family Rubredoxin_C PF18267.1 EGC36240.1 - 8.6 6.4 11.6 1.4 8.9 1.4 2.9 2 2 0 2 2 2 0 Rubredoxin NAD+ reductase C-terminal domain FNIP PF05725.12 EGC36241.1 - 5.1e-58 193.0 64.2 2.5e-11 43.5 1.9 9.2 4 3 6 11 11 11 11 FNIP Repeat Get5_bdg PF16843.5 EGC36241.1 - 0.0089 15.5 0.0 3.4 7.2 0.0 2.8 2 0 0 2 2 2 2 Binding domain to Get4 on Get5, Golgi to ER traffic protein zf_C2H2_10 PF18414.1 EGC36242.1 - 0.34 10.5 5.0 0.42 10.2 1.1 3.0 3 1 0 3 3 3 0 C2H2 type zinc-finger COMPASS-Shg1 PF05205.12 EGC36242.1 - 0.4 11.4 5.2 0.41 11.4 3.5 1.7 1 1 1 2 2 2 0 COMPASS (Complex proteins associated with Set1p) component shg1 YlqD PF11068.8 EGC36242.1 - 1.4 9.3 13.0 1.8 9.0 12.5 1.4 1 1 0 1 1 1 0 YlqD protein DUF3152 PF11350.8 EGC36243.1 - 0.11 12.2 0.0 0.18 11.4 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3152) LAGLIDADG_1 PF00961.19 EGC36243.1 - 2.1 9.4 7.5 0.84 10.6 3.9 2.2 2 1 0 2 2 2 0 LAGLIDADG endonuclease GST_N_5 PF18485.1 EGC36244.1 - 0.13 12.6 0.0 0.32 11.4 0.0 1.7 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain WD40 PF00400.32 EGC36245.1 - 6.5e-38 128.1 23.6 7.9e-06 26.5 0.1 9.5 9 0 0 9 9 9 8 WD domain, G-beta repeat DENN PF02141.21 EGC36245.1 - 2.5e-34 118.8 5.1 2.5e-34 118.8 5.1 2.4 2 1 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.18 EGC36245.1 - 2.8e-13 50.4 0.0 2.1e-12 47.6 0.0 2.6 2 0 0 2 2 2 1 uDENN domain ANAPC4_WD40 PF12894.7 EGC36245.1 - 3.3e-09 36.9 1.8 0.033 14.5 0.1 4.9 2 1 3 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain SBF2 PF12335.8 EGC36245.1 - 0.00095 18.8 4.2 0.0037 16.9 4.2 2.1 1 0 0 1 1 1 1 Myotubularin protein TPR_17 PF13431.6 EGC36246.1 - 0.0034 17.7 0.9 25 5.6 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat HTH_26 PF13443.6 EGC36246.1 - 0.024 15.0 0.0 3 8.3 0.0 2.9 2 0 0 2 2 2 0 Cro/C1-type HTH DNA-binding domain RP-C_C PF11800.8 EGC36248.1 - 0.17 12.0 1.0 0.2 11.7 1.0 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_S49_N PF08496.10 EGC36248.1 - 0.47 10.5 7.4 0.67 10.0 7.4 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal NTP_transferase PF00483.23 EGC36249.1 - 2.9e-50 171.2 0.0 3.8e-50 170.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.24 EGC36249.1 - 2.3e-09 36.6 10.6 3.3e-07 29.8 0.5 4.2 3 1 2 5 5 5 2 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.7 EGC36249.1 - 7.8e-09 36.1 0.0 9.6e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.6 EGC36249.1 - 0.017 14.9 8.7 0.15 11.8 0.7 4.4 3 1 1 4 4 4 0 Hexapeptide repeat of succinyl-transferase DUF4954 PF16314.5 EGC36249.1 - 0.043 12.0 0.1 0.064 11.4 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4954) Fucokinase PF07959.12 EGC36249.1 - 0.14 11.0 0.2 1.4 7.8 0.3 2.1 1 1 0 1 1 1 0 L-fucokinase GpcrRhopsn4 PF10192.9 EGC36250.1 - 1.6e-17 63.8 28.0 8.3e-17 61.4 14.5 2.7 1 1 1 2 2 2 2 Rhodopsin-like GPCR transmembrane domain ORF6N PF10543.9 EGC36251.1 - 9 6.6 7.7 6.9 6.9 0.8 3.2 3 1 0 3 3 3 0 ORF6N domain DDE_3 PF13358.6 EGC36252.1 - 5.2e-09 36.0 0.1 5.2e-09 36.0 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RING_2 PF13639.6 EGC36253.1 - 2.1e-11 44.0 9.4 3.5e-11 43.3 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC36253.1 - 9.3e-09 35.0 10.6 1.9e-08 34.0 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC36253.1 - 1e-08 34.9 6.2 1.6e-08 34.3 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC36253.1 - 3.1e-08 33.3 8.8 5.4e-08 32.6 8.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC36253.1 - 3.2e-07 30.5 7.1 9.1e-07 29.1 7.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC36253.1 - 1.5e-06 28.0 9.1 2.8e-06 27.2 9.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC36253.1 - 2.6e-06 27.2 5.5 5.4e-06 26.2 5.5 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC36253.1 - 6.5e-06 26.1 3.3 9.4e-06 25.6 1.9 2.0 1 1 1 2 2 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC36253.1 - 0.00075 19.6 8.6 0.0022 18.1 8.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC36253.1 - 0.013 15.3 10.5 0.024 14.4 10.5 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC36253.1 - 0.016 15.3 2.8 0.04 14.1 2.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC36253.1 - 0.017 15.2 2.1 0.034 14.2 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Antimicrobial19 PF08225.11 EGC36253.1 - 0.1 12.2 1.3 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Pseudin antimicrobial peptide zf-RING_11 PF17123.5 EGC36253.1 - 0.48 10.2 7.3 0.97 9.2 7.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger PAH PF02671.21 EGC36253.1 - 2.2 8.5 5.6 24 5.2 0.4 2.6 2 0 0 2 2 2 0 Paired amphipathic helix repeat Zn_ribbon_17 PF17120.5 EGC36253.1 - 3.4 7.4 6.5 5.6 6.7 6.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ThiF PF00899.21 EGC36255.1 - 2.7e-20 72.8 0.0 6.6e-20 71.5 0.0 1.7 1 1 0 1 1 1 1 ThiF family E1_4HB PF16191.5 EGC36255.1 - 8.1e-08 32.3 0.3 0.0047 17.1 0.0 3.6 3 0 0 3 3 3 3 Ubiquitin-activating enzyme E1 four-helix bundle Ctr PF04145.15 EGC36256.1 - 1e-17 65.2 19.4 1.1e-09 39.0 11.5 2.2 1 1 1 2 2 2 2 Ctr copper transporter family MFS_1 PF07690.16 EGC36256.1 - 0.00068 18.7 4.1 0.00088 18.3 4.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MIF4G PF02854.19 EGC36256.1 - 0.0019 17.9 1.5 0.0026 17.4 1.5 1.1 1 0 0 1 1 1 1 MIF4G domain SpoIIM PF01944.17 EGC36256.1 - 0.011 15.8 8.2 0.018 15.1 8.1 1.5 1 1 0 1 1 1 0 Stage II sporulation protein M Phage_holin_T PF11031.8 EGC36256.1 - 0.034 13.6 0.1 0.044 13.3 0.1 1.2 1 0 0 1 1 1 0 Bacteriophage T holin PTEN_C2 PF10409.9 EGC36257.1 - 4e-10 39.6 2.8 4e-10 39.6 2.8 2.4 3 0 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.20 EGC36257.1 - 2.3e-07 30.7 0.0 2.3e-07 30.7 0.0 3.6 5 1 0 5 5 5 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGC36257.1 - 0.0044 16.7 0.0 0.011 15.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGC36257.1 - 0.008 16.2 0.0 0.017 15.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.6 EGC36257.1 - 0.066 13.3 4.2 0.093 12.8 0.0 3.1 2 1 1 3 3 3 0 Inositol hexakisphosphate GCFC PF07842.12 EGC36258.1 - 1.3e-20 74.1 5.2 8.6e-20 71.5 3.8 3.0 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein RE_TdeIII PF09520.10 EGC36259.1 - 0.0022 17.7 0.1 0.0092 15.7 0.0 2.0 2 0 0 2 2 2 1 Type II restriction endonuclease, TdeIII FeoB_Cyto PF17910.1 EGC36259.1 - 0.045 14.3 0.6 6.4 7.4 0.0 2.5 2 0 0 2 2 2 0 FeoB cytosolic helical domain DUF2959 PF11172.8 EGC36259.1 - 0.053 13.6 2.9 0.74 9.9 0.1 2.8 2 1 0 3 3 3 0 Protein of unknown function (DUF2959) Asp4 PF16996.5 EGC36259.1 - 0.13 12.0 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Accessory secretory protein Sec Asp4 DUF4187 PF13821.6 EGC36260.1 - 1.7 8.5 5.7 3.8 7.4 5.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4187) NUDIX PF00293.28 EGC36264.1 - 1.1e-19 70.7 0.1 1.3e-19 70.5 0.1 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.6 EGC36264.1 - 5.9e-09 35.9 0.0 7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.6 EGC36264.1 - 0.0075 15.9 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase A_deaminase PF00962.22 EGC36265.1 - 8e-85 285.1 0.1 2.1e-73 247.5 0.0 2.1 2 0 0 2 2 2 2 Adenosine/AMP deaminase Glyco_transf_25 PF01755.17 EGC36266.1 - 0.00089 19.2 0.3 0.0014 18.6 0.3 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) 5_nucleotid PF05761.14 EGC36267.1 - 2.7e-57 194.7 5.2 5.2e-57 193.8 4.0 1.6 1 1 1 2 2 2 1 5' nucleotidase family CIMR PF00878.18 EGC36267.1 - 0.018 15.1 0.4 0.045 13.8 0.4 1.6 1 0 0 1 1 1 0 Cation-independent mannose-6-phosphate receptor repeat Hydrolase PF00702.26 EGC36267.1 - 0.07 13.4 0.0 0.17 12.2 0.0 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FTO_CTD PF12934.7 EGC36268.1 - 0.085 12.6 4.0 0.74 9.6 1.5 2.2 2 0 0 2 2 2 0 FTO C-terminal domain DUF1302 PF06980.11 EGC36268.1 - 1.1 7.8 5.9 1.6 7.2 5.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1302) Ras PF00071.22 EGC36269.1 - 5.6e-48 162.6 0.4 7e-48 162.3 0.4 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC36269.1 - 7.3e-29 100.4 0.1 1.2e-28 99.7 0.1 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC36269.1 - 3.7e-19 68.8 0.3 4.5e-19 68.5 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC36269.1 - 1.4e-07 31.1 0.3 1.8e-07 30.8 0.3 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC36269.1 - 1.9e-05 24.7 0.0 3.2e-05 24.0 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC36269.1 - 2.3e-05 24.0 0.2 0.00034 20.2 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGC36269.1 - 0.0022 17.7 0.1 1 9.1 0.1 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGC36269.1 - 0.014 14.8 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_24 PF13479.6 EGC36269.1 - 0.019 14.7 0.3 0.025 14.3 0.3 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGC36269.1 - 0.023 14.7 0.2 0.065 13.3 0.0 1.8 2 1 0 2 2 2 0 AAA domain AAA_22 PF13401.6 EGC36269.1 - 0.045 14.0 0.0 0.11 12.8 0.0 1.8 1 1 0 1 1 1 0 AAA domain TniB PF05621.11 EGC36269.1 - 0.074 12.5 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein Cupin_4 PF08007.12 EGC36270.1 - 1.3e-64 218.7 0.0 1.8e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.6 EGC36270.1 - 8.5e-09 35.5 0.5 3.8e-07 30.1 0.5 2.5 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.11 EGC36270.1 - 0.0041 16.8 0.0 0.043 13.5 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Cupin_1 PF00190.22 EGC36270.1 - 0.0092 15.6 0.0 0.016 14.8 0.0 1.4 1 0 0 1 1 1 1 Cupin TetR_C_9 PF14514.6 EGC36270.1 - 0.013 15.7 0.0 0.34 11.0 0.0 2.3 1 1 1 2 2 2 0 Tetracyclin repressor-like, C-terminal domain FNIP PF05725.12 EGC36272.1 - 1.1e-79 262.3 36.6 1.5e-15 57.0 0.2 8.6 4 2 5 10 10 10 9 FNIP Repeat DUF1769 PF08588.10 EGC36272.1 - 0.02 15.1 8.7 2.6 8.3 0.1 5.7 5 2 2 7 7 7 0 Protein of unknown function (DUF1769) Bax1-I PF01027.20 EGC36273.1 - 1.1e-26 94.0 22.9 1.2e-26 93.8 22.9 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 SUKH-4 PF14435.6 EGC36273.1 - 0.12 12.4 0.0 0.18 11.8 0.0 1.1 1 0 0 1 1 1 0 SUKH-4 immunity protein DUF2157 PF09925.9 EGC36273.1 - 0.13 12.1 6.7 0.41 10.4 0.6 2.7 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) MotA_ExbB PF01618.16 EGC36273.1 - 0.13 12.0 0.1 4.3 7.1 0.0 2.3 2 0 0 2 2 2 0 MotA/TolQ/ExbB proton channel family DUF5445 PF17520.2 EGC36273.1 - 0.16 11.8 0.0 0.16 11.8 0.0 3.0 3 1 1 4 4 4 0 Family of unknown function (DUF5445) 7TMR-DISM_7TM PF07695.11 EGC36273.1 - 1.7 8.5 24.8 7.8 6.3 21.3 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF308 PF03729.13 EGC36273.1 - 7.8 6.9 14.4 0.23 11.8 2.5 3.2 2 1 0 2 2 2 0 Short repeat of unknown function (DUF308) Bax1-I PF01027.20 EGC36274.1 - 7.1e-16 58.7 32.9 8.4e-16 58.4 32.9 1.1 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Vma12 PF11712.8 EGC36274.1 - 0.02 15.0 0.2 0.02 15.0 0.2 2.4 1 1 1 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase V-SNARE PF05008.15 EGC36275.1 - 0.027 14.8 3.2 0.12 12.8 3.1 2.2 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SPT16 PF08644.11 EGC36275.1 - 0.069 13.3 5.2 0.094 12.9 5.2 1.3 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Sgf11 PF08209.11 EGC36276.1 - 1.4e-09 37.3 0.5 2.6e-09 36.5 0.5 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) BUD22 PF09073.10 EGC36276.1 - 0.0026 17.2 10.2 0.0026 17.2 10.2 6.3 2 2 4 6 6 6 1 BUD22 RPN2_C PF18004.1 EGC36277.1 - 1.5e-45 155.0 13.9 1.5e-45 155.0 13.9 2.1 2 0 0 2 2 2 1 26S proteasome regulatory subunit RPN2 C-terminal domain PC_rep PF01851.22 EGC36277.1 - 5.6e-36 121.2 28.4 6.7e-06 26.3 0.1 9.2 9 0 0 9 9 8 8 Proteasome/cyclosome repeat HEAT_2 PF13646.6 EGC36277.1 - 9.2e-16 58.0 0.1 2.3e-11 43.9 0.0 3.4 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.22 EGC36277.1 - 0.00029 20.8 0.2 0.73 10.3 0.1 4.4 5 0 0 5 5 4 1 HEAT repeat HEAT_EZ PF13513.6 EGC36277.1 - 0.0069 16.9 0.6 0.54 10.8 0.0 3.9 3 1 1 4 4 3 1 HEAT-like repeat Btz PF09405.10 EGC36277.1 - 0.023 15.0 6.8 0.056 13.7 6.8 1.6 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding HEAT_PBS PF03130.16 EGC36277.1 - 0.03 15.0 1.9 5.3 8.0 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Cnd1 PF12717.7 EGC36277.1 - 0.081 13.0 5.5 3 7.9 0.0 3.9 3 1 1 4 4 4 0 non-SMC mitotic condensation complex subunit 1 PA26 PF04636.13 EGC36277.1 - 0.1 11.5 4.1 0.16 10.8 4.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Clathrin_H_link PF13838.6 EGC36277.1 - 0.12 12.3 0.0 0.31 11.0 0.0 1.6 1 0 0 1 1 1 0 Clathrin-H-link DUF2052 PF09747.9 EGC36277.1 - 0.75 9.9 13.5 0.036 14.2 7.9 1.7 2 0 0 2 2 1 0 Coiled-coil domain containing protein (DUF2052) CAF-1_p150 PF11600.8 EGC36277.1 - 1.4 8.6 24.7 0.2 11.4 20.4 1.7 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Presenilin PF01080.17 EGC36277.1 - 1.6 7.4 8.6 2.7 6.7 8.6 1.3 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC36277.1 - 1.6 6.9 8.7 3 6.0 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein RR_TM4-6 PF06459.12 EGC36277.1 - 4.7 7.0 14.8 1.3 8.7 11.5 1.7 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 LMBR1 PF04791.16 EGC36278.1 - 1.5 7.7 15.8 1.7 7.5 15.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein zf-C2H2_aberr PF17017.5 EGC36278.1 - 1.8 8.7 13.1 0.94 9.6 9.1 2.3 1 1 1 2 2 2 0 Aberrant zinc-finger DUF1479 PF07350.12 EGC36280.1 - 2.2e-07 30.0 0.4 0.004 16.0 0.1 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EGC36280.1 - 0.0001 22.6 0.0 0.0051 17.1 0.0 2.3 2 0 0 2 2 2 1 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_3 PF13640.6 EGC36280.1 - 0.0015 19.4 0.0 0.0033 18.3 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Latexin PF06907.12 EGC36281.1 - 0.0014 18.2 0.7 0.002 17.6 0.7 1.2 1 0 0 1 1 1 1 Latexin GST_C PF00043.25 EGC36282.1 - 2.2e-12 47.0 0.0 4.3e-12 46.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC36282.1 - 1.3e-11 44.6 1.0 2.5e-11 43.8 0.1 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC36282.1 - 1.7e-11 44.3 0.0 3.1e-11 43.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC36282.1 - 4.3e-10 39.5 0.0 7.8e-10 38.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC36282.1 - 3.7e-09 36.7 0.0 8.3e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC36282.1 - 3.9e-08 33.4 0.1 7.8e-08 32.4 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC36282.1 - 0.16 11.8 0.0 0.33 10.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.21 EGC36283.1 - 3.1e-65 220.7 0.0 3.6e-65 220.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.20 EGC36283.1 - 3.7e-08 32.3 0.0 1.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_5 PF00266.19 EGC36283.1 - 9.5e-08 31.4 0.0 1.8e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGC36283.1 - 4.8e-06 26.1 0.0 7.6e-06 25.4 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGC36283.1 - 0.011 15.1 0.0 0.017 14.5 0.0 1.2 1 0 0 1 1 1 0 DegT/DnrJ/EryC1/StrS aminotransferase family KNTase_C PF07827.11 EGC36283.1 - 0.021 14.7 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 KNTase C-terminal domain Met_gamma_lyase PF06838.11 EGC36283.1 - 0.043 12.3 0.0 0.087 11.3 0.0 1.4 1 1 0 1 1 1 0 Methionine gamma-lyase Homeodomain PF00046.29 EGC36284.1 - 2.6e-14 52.8 7.1 7.5e-08 32.1 2.4 2.8 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC36284.1 - 0.00013 21.8 6.5 0.012 15.5 0.0 3.3 3 0 0 3 3 3 2 Homeobox KN domain FRB_dom PF08771.11 EGC36284.1 - 3.7 8.0 6.7 4.7 7.7 0.3 2.7 2 0 0 2 2 2 0 FKBP12-rapamycin binding domain DUF2778 PF10908.8 EGC36285.1 - 2.7e-20 72.8 0.9 6.9e-20 71.5 0.9 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2778) Nucleoporin_FG PF13634.6 EGC36286.1 - 2e-11 44.5 176.0 0.00067 20.4 24.2 8.4 4 1 4 8 8 8 7 Nucleoporin FG repeat region NAD_binding_6 PF08030.12 EGC36287.1 - 1.2e-29 103.5 0.0 1.9e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain Ferric_reduct PF01794.19 EGC36287.1 - 1e-21 77.4 8.8 2.1e-21 76.3 8.8 1.6 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_8 PF08022.12 EGC36287.1 - 6.6e-21 74.4 0.0 1.3e-20 73.5 0.0 1.5 1 0 0 1 1 1 1 FAD-binding domain FAD_binding_6 PF00970.24 EGC36287.1 - 0.00046 20.5 0.0 0.001 19.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGC36287.1 - 0.038 14.6 0.0 0.16 12.6 0.0 2.0 2 0 0 2 2 2 0 Oxidoreductase NAD-binding domain MFS_1 PF07690.16 EGC36288.1 - 1.2e-26 93.5 25.5 1.1e-23 83.8 5.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.13 EGC36288.1 - 1.7e-24 86.1 9.4 6.1e-21 74.4 3.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Halogen_Hydrol PF10112.9 EGC36288.1 - 1.1 9.2 0.0 1.1 9.2 0.0 2.9 3 0 0 3 3 3 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein DUF3149 PF11346.8 EGC36288.1 - 3.1 7.5 6.3 1.8 8.2 0.2 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3149) NADH_B2 PF14813.6 EGC36289.1 - 0.1 12.4 0.6 0.28 11.0 0.6 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 Peptidase_C48 PF02902.19 EGC36291.1 - 3.1e-31 108.9 4.3 3.1e-31 108.9 4.3 2.7 2 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain REPA_OB_2 PF16900.5 EGC36292.1 - 5.9e-16 58.2 2.7 5.9e-16 58.2 2.7 2.6 3 0 0 3 3 3 1 Replication protein A OB domain tRNA_anti-codon PF01336.25 EGC36292.1 - 3.2e-13 49.5 0.0 2.2e-05 24.3 0.1 3.3 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EGC36292.1 - 9.8e-11 41.8 0.2 1.6e-09 37.8 0.1 2.4 2 1 0 2 2 2 1 Cell division control protein 24, OB domain 3 Rep_fac-A_C PF08646.10 EGC36292.1 - 3.7e-05 23.5 4.1 3.7e-05 23.5 4.1 3.9 4 0 0 4 4 4 1 Replication factor-A C terminal domain DUF4834 PF16118.5 EGC36292.1 - 0.52 11.3 4.2 0.37 11.8 0.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Roughex PF06020.11 EGC36292.1 - 1.6 7.7 9.0 3.1 6.8 9.0 1.4 1 0 0 1 1 1 0 Drosophila roughex protein Ndc1_Nup PF09531.10 EGC36292.1 - 3 6.4 8.4 4 6.0 8.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup COG5 PF10392.9 EGC36293.1 - 4.2e-23 82.0 3.4 4.2e-23 82.0 3.4 4.5 3 1 1 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.11 EGC36293.1 - 1.7e-11 44.3 3.3 1.7e-11 44.3 3.3 2.9 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 DUF5343 PF17278.2 EGC36293.1 - 0.0059 16.7 0.1 6 6.9 0.0 3.2 2 0 0 2 2 2 2 Family of unknown function (DUF5343) Vps51 PF08700.11 EGC36293.1 - 0.0078 16.3 1.0 0.0078 16.3 1.0 3.7 3 0 0 3 3 3 1 Vps51/Vps67 F-box-like_2 PF13013.6 EGC36293.1 - 0.05 13.6 0.6 2.4 8.2 0.1 2.8 2 0 0 2 2 2 0 F-box-like domain GspL_C PF12693.7 EGC36293.1 - 0.055 13.3 1.3 0.14 12.0 0.5 2.0 2 0 0 2 2 2 0 GspL periplasmic domain BLOC1_2 PF10046.9 EGC36293.1 - 2.4 8.5 17.3 0.11 12.8 1.0 5.0 4 1 1 5 5 5 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Q_salvage PF10343.9 EGC36294.1 - 2.1e-87 293.3 0.0 3e-87 292.8 0.0 1.2 1 0 0 1 1 1 1 Potential Queuosine, Q, salvage protein family DUF1688 PF07958.11 EGC36294.1 - 0.0065 15.2 0.0 0.62 8.7 0.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1688) FNIP PF05725.12 EGC36295.1 - 3.6e-21 75.1 29.9 3.8e-05 23.8 1.4 4.7 1 1 4 6 6 6 6 FNIP Repeat SNRNP27 PF08648.12 EGC36295.1 - 0.018 15.1 7.1 10 6.2 0.0 4.0 4 0 0 4 4 4 0 U4/U6.U5 small nuclear ribonucleoproteins DUF2824 PF11039.8 EGC36295.1 - 0.12 12.4 0.0 1.5 8.7 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2824) TOBE_3 PF12857.7 EGC36295.1 - 0.16 11.9 0.0 1.2e+02 2.7 0.0 3.1 3 0 0 3 3 3 0 TOBE-like domain Thaumatin PF00314.17 EGC36295.1 - 0.27 10.9 0.0 31 4.1 0.0 3.2 1 1 3 4 4 4 0 Thaumatin family SR-25 PF10500.9 EGC36296.1 - 2.2 7.8 8.1 2.7 7.6 8.1 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HEAT_2 PF13646.6 EGC36298.1 - 8.1e-05 22.9 0.1 0.074 13.4 0.0 3.0 2 1 0 2 2 2 2 HEAT repeats HEAT PF02985.22 EGC36298.1 - 0.00017 21.6 12.3 0.23 11.8 0.0 6.6 8 0 0 8 8 8 2 HEAT repeat MOR2-PAG1_C PF14225.6 EGC36298.1 - 0.01 15.7 1.3 0.11 12.3 0.0 2.6 2 0 0 2 2 2 0 Cell morphogenesis C-terminal LisH PF08513.11 EGC36298.1 - 0.019 14.9 3.4 0.033 14.1 0.2 2.7 2 0 0 2 2 2 0 LisH Vac14_Fab1_bd PF12755.7 EGC36298.1 - 0.091 13.4 0.0 49 4.6 0.0 3.7 2 1 0 2 2 2 0 Vacuolar 14 Fab1-binding region DUF1664 PF07889.12 EGC36299.1 - 0.0054 16.8 3.2 0.011 15.8 0.8 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF1664) DUF883 PF05957.13 EGC36299.1 - 0.011 16.3 0.3 0.98 10.1 0.0 2.2 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) ApoO PF09769.9 EGC36299.1 - 0.012 15.5 0.7 0.051 13.5 0.1 1.8 1 1 1 2 2 2 0 Apolipoprotein O Rab5-bind PF09311.11 EGC36299.1 - 0.025 14.0 1.3 0.035 13.5 1.3 1.2 1 0 0 1 1 1 0 Rabaptin-like protein TPR_21 PF09976.9 EGC36299.1 - 0.038 13.7 0.5 0.038 13.7 0.5 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat-like domain Golgin_A5 PF09787.9 EGC36299.1 - 0.047 13.1 1.3 0.06 12.8 1.3 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 DUF5610 PF18433.1 EGC36299.1 - 0.1 13.1 3.2 0.11 13.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF5610) COG2 PF06148.11 EGC36299.1 - 0.11 12.6 0.8 0.33 11.0 0.4 1.8 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF3708 PF12501.8 EGC36299.1 - 0.17 11.6 0.0 0.23 11.3 0.0 1.3 1 0 0 1 1 1 0 Phosphate ATP-binding cassette transporter Tape_meas_lam_C PF09718.10 EGC36299.1 - 0.32 11.1 4.9 0.19 11.9 1.6 2.0 1 1 1 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) SNARE PF05739.19 EGC36299.1 - 0.51 10.4 3.5 4.1 7.5 0.5 2.8 3 0 0 3 3 3 0 SNARE domain YtxH PF12732.7 EGC36299.1 - 0.66 10.6 6.5 2.5 8.7 4.3 2.4 1 1 0 1 1 1 0 YtxH-like protein DNTTIP1_dimer PF18192.1 EGC36299.1 - 6.8 7.1 8.2 5.7e+02 1.0 8.2 2.8 1 1 0 1 1 1 0 DNTTIP1 dimerisation domain FAD_binding_4 PF01565.23 EGC36301.1 - 1e-26 93.4 0.3 1.5e-26 92.8 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC36301.1 - 2.2e-06 27.7 0.3 4.4e-06 26.7 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like ExsD PF16806.5 EGC36301.1 - 0.089 12.7 0.0 0.16 11.9 0.0 1.3 1 0 0 1 1 1 0 Antiactivator protein ExsD SHNi-TPR PF10516.9 EGC36301.1 - 1.9 8.0 4.1 4.5 6.8 0.1 3.0 3 0 0 3 3 3 0 SHNi-TPR FAD_binding_4 PF01565.23 EGC36302.1 - 7.9e-26 90.5 0.0 1.4e-25 89.6 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC36302.1 - 1.8e-09 37.5 0.4 3.4e-09 36.7 0.4 1.5 1 0 0 1 1 1 1 Berberine and berberine like SmaI PF17411.2 EGC36305.1 - 0.059 12.5 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 Type II site-specific deoxyribonuclease Ribosomal_L7Ae PF01248.26 EGC36306.1 - 1.1e-19 69.9 1.4 1.9e-19 69.2 1.4 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family LRR_6 PF13516.6 EGC36307.1 - 0.0012 18.8 48.6 1.3 9.2 0.1 11.6 13 0 0 13 13 13 6 Leucine Rich repeat F-box-like PF12937.7 EGC36307.1 - 0.0019 18.1 0.0 0.0042 17.0 0.0 1.6 1 0 0 1 1 1 1 F-box-like PARG_cat PF05028.14 EGC36307.1 - 0.031 13.6 0.9 0.06 12.6 0.9 1.4 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) Pkinase PF00069.25 EGC36308.1 - 1.3e-35 123.0 0.0 1.8e-35 122.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36308.1 - 2.5e-35 122.0 0.1 3.1e-35 121.7 0.1 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.8 EGC36308.1 - 0.00074 19.2 1.2 0.0019 17.9 0.0 2.1 3 0 0 3 3 3 1 Protein-kinase domain of FAM69 Haspin_kinase PF12330.8 EGC36308.1 - 0.012 14.6 0.1 0.02 13.8 0.0 1.4 2 0 0 2 2 2 0 Haspin like kinase domain WH1 PF00568.23 EGC36309.1 - 3.2e-18 65.7 0.1 4.2e-18 65.3 0.1 1.2 1 0 0 1 1 1 1 WH1 domain VASP_tetra PF08776.11 EGC36309.1 - 1e-09 37.8 4.8 1e-09 37.8 4.8 1.5 2 0 0 2 2 2 1 VASP tetramerisation domain WH2 PF02205.20 EGC36309.1 - 4.5e-09 35.9 0.2 4.5e-09 35.9 0.2 2.4 3 0 0 3 3 3 1 WH2 motif PIG-S PF10510.9 EGC36310.1 - 3e-103 346.4 13.2 1.2e-99 334.6 5.8 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Dicty_spore_N PF04562.12 EGC36311.1 - 0.0023 18.6 12.7 0.0023 18.6 12.7 6.8 4 2 4 8 8 8 2 Dictyostelium spore coat protein, N terminus Dsh_C PF12316.8 EGC36311.1 - 1.2 9.5 26.3 0.55 10.6 12.4 2.5 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CbtA PF09490.10 EGC36312.1 - 0.071 12.9 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Probable cobalt transporter subunit (CbtA) ATP-synt_8 PF00895.20 EGC36312.1 - 1.2 9.6 6.7 0.44 11.0 2.2 2.7 2 0 0 2 2 2 0 ATP synthase protein 8 DUF2975 PF11188.8 EGC36312.1 - 7.4 6.5 7.2 2 8.3 1.1 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2975) Rft-1 PF04506.13 EGC36313.1 - 5.3e-69 233.3 24.0 6.8e-69 233.0 24.0 1.1 1 0 0 1 1 1 1 Rft protein DUF1761 PF08570.10 EGC36313.1 - 0.05 13.9 10.5 0.19 12.0 2.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1761) BK_channel_a PF03493.18 EGC36313.1 - 0.052 13.7 0.2 0.17 12.0 0.1 2.1 1 1 0 1 1 1 0 Calcium-activated BK potassium channel alpha subunit Gemini_mov PF01708.16 EGC36313.1 - 0.056 13.2 2.6 0.7 9.7 0.6 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF2101 PF09874.9 EGC36313.1 - 2 8.1 20.0 0.059 13.1 13.5 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Polysacc_synt_C PF14667.6 EGC36313.1 - 6.2 6.9 21.5 0.29 11.2 15.5 1.9 2 0 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Secretin_N_2 PF07655.13 EGC36313.1 - 7.9 7.1 12.0 14 6.3 12.0 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain Arf PF00025.21 EGC36315.1 - 8.1e-66 220.8 0.2 9.6e-66 220.5 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGC36315.1 - 1.8e-13 50.4 0.0 2.1e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC36315.1 - 3.7e-13 49.8 0.0 5.2e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC36315.1 - 1.6e-12 47.2 0.0 1.8e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC36315.1 - 2.9e-09 36.5 2.7 1.3e-06 27.8 0.4 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC36315.1 - 9.6e-09 34.9 0.0 1.2e-08 34.7 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC36315.1 - 0.00016 21.7 0.0 0.00023 21.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF4003 PF13170.6 EGC36315.1 - 0.0099 15.3 0.0 0.013 14.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4003) ABC_tran PF00005.27 EGC36315.1 - 0.011 16.3 0.0 0.016 15.7 0.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGC36315.1 - 0.029 14.9 0.1 0.043 14.3 0.1 1.5 1 1 0 1 1 1 0 AAA domain KAP_NTPase PF07693.14 EGC36315.1 - 0.03 13.6 0.1 0.1 11.8 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Ectoine_synth PF06339.12 EGC36315.1 - 0.051 13.8 0.0 0.078 13.2 0.0 1.3 1 0 0 1 1 1 0 Ectoine synthase MeaB PF03308.16 EGC36315.1 - 0.12 11.4 0.0 6.3 5.7 0.0 2.1 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ECH_2 PF16113.5 EGC36316.1 - 2.5e-113 379.0 0.0 3.2e-113 378.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_1 PF00378.20 EGC36316.1 - 3.5e-29 101.8 0.0 6.2e-29 101.1 0.0 1.4 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase zf-UBR PF02207.20 EGC36317.1 - 2.5e-17 62.8 11.8 2.5e-17 62.8 11.8 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_5 PF14634.6 EGC36317.1 - 0.0079 16.1 1.0 0.0079 16.1 1.0 3.6 4 0 0 4 4 4 1 zinc-RING finger domain SET PF00856.28 EGC36318.1 - 6.8e-10 39.6 3.1 3.8e-09 37.2 3.1 2.1 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.18 EGC36318.1 - 0.0015 18.6 5.4 0.0015 18.6 5.4 2.2 2 0 0 2 2 2 1 MYND finger zf-Mss51 PF13824.6 EGC36318.1 - 0.19 11.9 2.6 0.71 10.0 2.6 2.0 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 LigB PF02900.18 EGC36319.1 - 1.1e-40 139.5 0.0 1.2e-40 139.4 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FKBP_C PF00254.28 EGC36320.1 - 1.4e-33 115.1 0.0 1.7e-33 114.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DIM PF08194.12 EGC36320.1 - 0.77 10.0 2.1 0.77 10.0 0.7 1.7 2 0 0 2 2 2 0 DIM protein Mito_carr PF00153.27 EGC36321.1 - 5.5e-73 241.0 0.8 4.6e-24 84.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGC36321.1 - 0.32 10.1 1.6 2 7.5 0.2 2.5 2 1 0 3 3 3 0 Gammaproteobacterial serine protease Keratin PF02422.16 EGC36322.1 - 0.15 11.8 0.1 0.32 10.7 0.0 1.6 2 0 0 2 2 2 0 Keratin DREV PF05219.12 EGC36324.1 - 8.4e-56 189.0 1.4 1.1e-55 188.5 1.4 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_11 PF08241.12 EGC36324.1 - 6.4e-10 39.6 0.0 1.6e-09 38.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36324.1 - 2.1e-09 38.0 0.0 9.6e-09 35.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36324.1 - 2.5e-07 30.7 0.0 3.9e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC36324.1 - 1.5e-05 25.6 0.0 3.7e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36324.1 - 4.8e-05 23.2 0.4 0.00013 21.7 0.4 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC36324.1 - 0.02 13.8 0.0 0.031 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF4092 PF13322.6 EGC36324.1 - 0.052 13.4 0.1 0.1 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4092) DUF5308 PF17233.2 EGC36325.1 - 0.041 14.1 2.4 0.058 13.6 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Zip PF02535.22 EGC36325.1 - 0.59 9.3 5.9 0.71 9.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC36325.1 - 5.6 5.6 7.5 6 5.5 7.5 1.1 1 0 0 1 1 1 0 Presenilin NUC129 PF08157.11 EGC36326.1 - 0.11 12.8 0.2 0.28 11.6 0.2 1.7 1 0 0 1 1 1 0 NUC129 domain R-HINP1I PF11463.8 EGC36327.1 - 0.042 13.3 0.9 0.082 12.3 0.2 1.8 2 1 0 2 2 2 0 R.HinP1I restriction endonuclease Mito_carr PF00153.27 EGC36327.1 - 0.069 13.1 0.2 0.42 10.6 0.0 2.3 3 0 0 3 3 3 0 Mitochondrial carrier protein BBS1 PF14779.6 EGC36328.1 - 0.0019 17.7 0.0 0.0039 16.7 0.0 1.5 1 0 0 1 1 1 1 Ciliary BBSome complex subunit 1 Med12 PF09497.10 EGC36329.1 - 1.2e-18 67.2 0.1 2.9e-18 65.9 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.8 EGC36329.1 - 2.3e-05 23.5 7.2 2.3e-05 23.5 7.2 4.6 4 2 0 4 4 4 1 Eukaryotic Mediator 12 subunit domain DUF2457 PF10446.9 EGC36329.1 - 3.6 6.6 22.2 14 4.7 22.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_7 PF13499.6 EGC36330.1 - 3.4e-10 40.2 1.1 2.9e-05 24.4 0.2 2.0 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC36330.1 - 2.4e-08 32.9 0.4 7.4e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.6 EGC36330.1 - 7.3e-08 31.7 0.1 0.00014 21.5 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.6 EGC36330.1 - 2.3e-05 23.7 0.1 0.00035 19.9 0.0 2.1 2 0 0 2 2 2 1 EF hand Tannase PF07519.11 EGC36330.1 - 0.00078 18.5 0.1 0.00078 18.5 0.1 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase EF-hand_8 PF13833.6 EGC36330.1 - 0.0052 16.6 0.1 0.14 12.0 0.1 2.3 2 0 0 2 2 2 1 EF-hand domain pair Caenor_Her-1 PF09232.10 EGC36330.1 - 0.058 13.5 0.0 0.062 13.4 0.0 1.1 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 Mif2_N PF15624.6 EGC36331.1 - 0.12 13.1 3.4 0.093 13.4 1.0 2.0 2 1 0 2 2 2 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Chromo PF00385.24 EGC36332.1 - 8.8e-07 28.7 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RT_RNaseH PF17917.1 EGC36333.1 - 2.2e-29 101.8 0.0 4.2e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase RT_RNaseH_2 PF17919.1 EGC36333.1 - 1.4e-26 92.4 0.0 2.5e-26 91.6 0.0 1.4 1 0 0 1 1 1 1 RNase H-like domain found in reverse transcriptase Integrase_H2C2 PF17921.1 EGC36333.1 - 6.8e-14 51.7 0.0 1.2e-13 50.9 0.0 1.4 1 0 0 1 1 1 1 Integrase zinc binding domain DUF397 PF04149.12 EGC36333.1 - 0.14 12.3 0.0 0.73 9.9 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF397) Coiled PF05710.12 EGC36334.1 - 8e-06 26.6 9.9 9.7e-06 26.3 9.9 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC36335.1 - 1.1e-05 26.1 9.8 1.3e-05 25.9 9.8 1.1 1 0 0 1 1 1 1 Coiled coil Atg31 PF09795.9 EGC36336.1 - 0.05 13.6 3.9 0.074 13.0 3.7 1.5 1 1 0 1 1 1 0 Autophagy-related protein 31 Remorin_C PF03763.13 EGC36336.1 - 0.1 12.5 1.8 0.14 12.1 1.8 1.2 1 0 0 1 1 1 0 Remorin, C-terminal region DUF737 PF05300.11 EGC36336.1 - 0.11 12.8 1.8 0.13 12.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF737) Carb_kinase PF01256.17 EGC36338.1 - 6.1e-53 179.8 0.0 7.8e-53 179.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.15 EGC36338.1 - 2.5e-05 23.8 0.0 4.5e-05 22.9 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Aim19 PF10315.9 EGC36338.1 - 0.022 15.1 0.0 0.043 14.1 0.0 1.4 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 19 Phos_pyr_kin PF08543.12 EGC36338.1 - 0.028 13.8 0.0 0.04 13.3 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase GATase PF00117.28 EGC36338.1 - 0.082 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine amidotransferase class-I TPR_8 PF13181.6 EGC36340.1 - 0.035 14.3 0.4 2.8 8.4 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC36340.1 - 0.15 12.4 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1604 PF07713.13 EGC36342.1 - 2.8e-35 120.0 1.9 2.8e-35 120.0 1.9 4.2 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) EphA2_TM PF14575.6 EGC36343.1 - 0.026 15.4 0.5 1.1 10.2 0.0 3.0 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain MARVEL PF01284.23 EGC36343.1 - 1 9.4 6.5 12 5.9 6.4 2.7 1 1 0 1 1 1 0 Membrane-associating domain DUF202 PF02656.15 EGC36343.1 - 1.2 9.6 8.6 2.9 8.4 2.7 3.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) Cyt_bd_oxida_II PF02322.15 EGC36343.1 - 3.2 7.0 6.8 17 4.6 6.8 1.9 1 1 0 1 1 1 0 Cytochrome bd terminal oxidase subunit II Iron_permease PF04120.12 EGC36343.1 - 3.8 7.3 5.9 9.2 6.1 0.4 3.5 2 1 2 4 4 4 0 Low affinity iron permease PH PF00169.29 EGC36344.1 - 4.9e-16 59.1 0.4 1.2e-15 57.8 0.4 1.7 1 0 0 1 1 1 1 PH domain TPR_12 PF13424.6 EGC36344.1 - 0.00026 21.2 0.0 0.068 13.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat PH_11 PF15413.6 EGC36344.1 - 0.0012 19.2 4.1 0.081 13.4 4.1 3.1 1 1 0 1 1 1 1 Pleckstrin homology domain QWRF PF04484.12 EGC36344.1 - 0.025 14.3 0.9 0.05 13.3 0.9 1.5 1 0 0 1 1 1 0 QWRF family RUN PF02759.19 EGC36344.1 - 0.29 11.1 4.5 2.5 8.1 0.1 3.2 3 0 0 3 3 3 0 RUN domain DUF948 PF06103.11 EGC36345.1 - 0.019 15.2 3.3 0.17 12.1 0.7 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) CK2S PF15011.6 EGC36345.1 - 0.16 11.9 1.0 0.64 9.9 0.3 2.1 2 1 0 2 2 2 0 Casein Kinase 2 substrate YbaJ PF10757.9 EGC36345.1 - 0.44 11.1 5.5 1.3 9.6 1.1 2.4 1 1 1 2 2 2 0 Biofilm formation regulator YbaJ V-SNARE_C PF12352.8 EGC36345.1 - 0.68 10.3 4.5 1.3 9.4 0.7 2.9 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus Fib_alpha PF08702.10 EGC36345.1 - 2.4 8.3 12.6 8.2 6.6 8.6 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family RabGAP-TBC PF00566.18 EGC36346.1 - 3.2e-53 180.6 0.1 3.2e-53 180.6 0.1 1.9 3 0 0 3 3 3 1 Rab-GTPase-TBC domain F-box-like PF12937.7 EGC36346.1 - 2.4e-08 33.7 1.6 8.6e-07 28.8 0.5 3.1 3 0 0 3 3 3 1 F-box-like F-box PF00646.33 EGC36346.1 - 6.8e-05 22.6 1.2 0.0002 21.1 1.2 1.7 1 0 0 1 1 1 1 F-box domain E2_bind PF08825.10 EGC36346.1 - 0.056 13.6 0.0 0.19 11.9 0.0 1.9 2 0 0 2 2 2 0 E2 binding domain Mucin PF01456.17 EGC36346.1 - 2.6 8.0 26.7 5.6 7.0 26.7 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MTS PF05175.14 EGC36347.1 - 0.00014 21.4 0.0 0.00025 20.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.6 EGC36347.1 - 0.13 13.0 0.0 0.3 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain OPT PF03169.15 EGC36348.1 - 1.2e-144 483.3 17.8 1.4e-144 483.1 17.8 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein DUF3093 PF11292.8 EGC36348.1 - 0.055 13.7 1.4 0.22 11.8 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3093) RseC_MucC PF04246.12 EGC36348.1 - 3.4 7.6 5.9 1.1 9.2 0.1 3.2 3 0 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC QCR10 PF09796.9 EGC36348.1 - 7.4 6.7 7.4 48 4.1 0.1 3.5 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) Zip PF02535.22 EGC36348.1 - 9.9 5.3 13.6 2.2 7.4 0.0 3.0 3 0 0 3 3 3 0 ZIP Zinc transporter tRNA-synt_1 PF00133.22 EGC36349.1 - 2.4e-59 201.1 6.6 3.7e-36 124.6 4.8 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.6 EGC36349.1 - 4.9e-41 140.3 0.3 2.6e-40 137.9 0.0 2.1 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.11 EGC36349.1 - 8.4e-31 107.1 0.1 5.7e-20 71.4 0.0 4.5 3 1 1 4 4 4 4 tRNA synthetases class I (M) Anticodon_1 PF08264.13 EGC36349.1 - 2.1e-09 37.5 0.0 5.4e-09 36.2 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGC36349.1 - 1.3e-05 24.7 0.0 0.098 12.0 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1f PF01921.18 EGC36349.1 - 0.0049 15.8 0.3 0.19 10.6 0.0 3.0 2 1 1 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1d PF00750.19 EGC36349.1 - 0.032 13.2 0.0 0.12 11.3 0.0 1.9 2 0 0 2 2 2 0 tRNA synthetases class I (R) Ogr_Delta PF04606.12 EGC36349.1 - 0.25 11.4 2.0 0.36 10.9 0.2 2.1 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger ABC2_membrane_3 PF12698.7 EGC36350.1 - 8.9e-38 130.3 37.7 1.3e-37 129.7 37.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.27 EGC36350.1 - 5.2e-28 98.3 0.0 8.5e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC36350.1 - 7.4e-09 35.8 1.5 1.1e-05 25.4 0.0 3.1 2 1 1 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_2 PF12679.7 EGC36350.1 - 0.0021 17.4 18.5 0.0048 16.2 18.5 1.5 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_15 PF13175.6 EGC36350.1 - 0.017 14.8 1.4 2.7 7.6 0.2 3.0 2 1 0 3 3 3 0 AAA ATPase domain SRP54 PF00448.22 EGC36350.1 - 0.16 11.6 0.2 0.3 10.7 0.2 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain 2OG-FeII_Oxy_3 PF13640.6 EGC36351.1 - 2.7e-10 41.0 1.2 4.1e-10 40.4 0.1 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily IKKbetaNEMObind PF12179.8 EGC36351.1 - 0.2 11.7 0.0 0.58 10.2 0.0 1.7 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain 2OG-FeII_Oxy_3 PF13640.6 EGC36352.1 - 4.7e-10 40.2 0.3 4.7e-10 40.2 0.3 1.8 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Kelch_4 PF13418.6 EGC36354.1 - 3.5e-35 119.7 10.9 8.6e-10 38.5 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC36354.1 - 1.6e-34 117.5 9.4 1.1e-09 38.3 0.0 7.9 7 0 0 7 7 7 5 Galactose oxidase, central domain RhoGAP PF00620.27 EGC36354.1 - 9.5e-33 113.2 0.1 9.5e-33 113.2 0.1 3.1 3 0 0 3 3 3 1 RhoGAP domain Kelch_5 PF13854.6 EGC36354.1 - 7.4e-30 102.4 10.2 2.6e-07 30.5 0.3 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC36354.1 - 2.1e-25 87.6 8.9 3.8e-06 26.6 0.0 7.5 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.6 EGC36354.1 - 1e-23 82.7 15.3 1.1e-08 35.1 0.1 7.0 3 2 3 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGC36354.1 - 1.8e-17 62.6 6.5 5.3e-07 29.1 0.0 6.6 6 1 0 6 6 6 3 Kelch motif IPPT PF01715.17 EGC36355.1 - 8.1e-49 166.5 1.3 1.5e-48 165.6 1.3 1.4 1 1 0 1 1 1 1 IPP transferase IPT PF01745.16 EGC36355.1 - 2.1e-05 24.1 0.5 0.00041 19.8 0.0 2.7 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.6 EGC36355.1 - 0.0022 18.2 0.1 0.0091 16.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain Hpr_kinase_C PF07475.12 EGC36355.1 - 0.0052 16.3 0.3 0.016 14.8 0.0 1.8 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain RNA_helicase PF00910.22 EGC36355.1 - 0.016 15.6 1.2 0.19 12.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase AAA_18 PF13238.6 EGC36355.1 - 0.023 15.2 0.0 0.023 15.2 0.0 3.6 3 1 0 3 3 3 0 AAA domain ABC_tran PF00005.27 EGC36355.1 - 0.039 14.5 0.3 0.039 14.5 0.3 2.3 2 1 0 2 2 2 0 ABC transporter AAA_16 PF13191.6 EGC36355.1 - 0.044 14.2 0.0 0.12 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Ploopntkinase3 PF18751.1 EGC36355.1 - 0.082 12.8 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 EGC36355.1 - 0.09 12.5 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_17 PF13207.6 EGC36355.1 - 0.2 12.1 6.4 5.1 7.5 0.0 3.0 3 0 0 3 3 3 0 AAA domain Hydin_ADK PF17213.3 EGC36355.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.5 3 0 0 3 3 3 0 Hydin Adenylate kinase-like domain PP2C_C PF07830.13 EGC36355.1 - 0.23 11.9 2.7 3.9 8.0 0.6 2.9 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain AAA PF00004.29 EGC36355.1 - 0.27 11.6 1.6 0.48 10.9 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UBX PF00789.20 EGC36356.1 - 2e-12 47.2 0.0 4.6e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.23 EGC36356.1 - 0.0019 17.9 0.3 0.017 14.8 0.0 2.8 3 1 1 4 4 4 1 Ubiquitin family Thioredoxin_7 PF13899.6 EGC36356.1 - 0.01 16.0 0.1 0.043 14.0 0.0 2.1 3 0 0 3 3 3 0 Thioredoxin-like DUF393 PF04134.12 EGC36357.1 - 5.9e-25 88.8 0.0 7.6e-25 88.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 LRR_6 PF13516.6 EGC36358.1 - 0.0018 18.1 27.0 2.1 8.6 0.5 8.3 9 0 0 9 9 9 3 Leucine Rich repeat DUF2251 PF10008.9 EGC36358.1 - 0.056 13.5 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2251) LRR_1 PF00560.33 EGC36358.1 - 0.54 11.0 6.8 20 6.2 0.0 5.9 6 0 0 6 6 6 0 Leucine Rich Repeat Sld5 PF05916.11 EGC36359.1 - 4.7e-08 33.5 0.0 9.7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein TAF1_subA PF14929.6 EGC36359.1 - 0.063 12.7 0.1 0.077 12.4 0.1 1.1 1 0 0 1 1 1 0 TAF RNA Polymerase I subunit A RdRP PF05183.12 EGC36360.1 - 5.2e-131 438.1 0.8 8.8e-131 437.4 0.0 1.8 3 0 0 3 3 3 1 RNA dependent RNA polymerase Helicase_C PF00271.31 EGC36360.1 - 2.3e-21 76.2 2.4 6e-20 71.6 0.1 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC36360.1 - 4.1e-15 56.0 1.9 1.1e-14 54.6 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.15 EGC36360.1 - 4.2e-15 56.2 0.0 4.2e-15 56.2 0.0 2.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Tmpp129 PF10272.9 EGC36360.1 - 0.038 13.3 3.4 0.065 12.5 1.7 2.2 2 0 0 2 2 2 0 Putative transmembrane protein precursor VASt PF16016.5 EGC36361.1 - 0.0002 21.8 0.0 0.00022 21.6 0.0 1.0 1 0 0 1 1 1 1 VAD1 Analog of StAR-related lipid transfer domain ABC_tran PF00005.27 EGC36362.1 - 1.8e-27 96.6 0.0 4.8e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.7 EGC36362.1 - 1.9e-23 83.2 36.2 2.9e-23 82.5 36.2 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGC36362.1 - 1.4e-13 51.4 0.2 9e-09 35.6 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC36362.1 - 3.7e-05 23.3 0.0 8.8e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.22 EGC36362.1 - 0.044 13.4 0.2 0.1 12.2 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain DUF4162 PF13732.6 EGC36362.1 - 0.09 13.5 2.1 0.12 13.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_23 PF13476.6 EGC36362.1 - 0.11 13.0 0.2 0.11 13.0 0.2 2.5 1 1 1 2 2 2 0 AAA domain AAA_30 PF13604.6 EGC36362.1 - 0.2 11.4 0.1 0.35 10.6 0.1 1.3 1 0 0 1 1 1 0 AAA domain adh_short PF00106.25 EGC36363.1 - 3.1e-42 144.3 0.0 3.8e-42 144.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36363.1 - 2.9e-25 89.2 0.0 3.6e-25 88.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36363.1 - 1.6e-05 24.9 0.0 2.2e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC36363.1 - 0.00018 20.8 0.0 0.00028 20.1 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGC36363.1 - 0.03 13.8 0.1 0.062 12.8 0.0 1.5 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Sacchrp_dh_NADP PF03435.18 EGC36363.1 - 0.039 14.2 0.1 0.063 13.5 0.1 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain 3HCDH_N PF02737.18 EGC36363.1 - 0.06 13.2 0.0 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.28 EGC36364.1 - 1.2e-56 192.7 0.1 1.4e-56 192.5 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LMP PF04778.12 EGC36364.1 - 0.12 12.3 2.5 0.28 11.1 0.2 2.5 3 0 0 3 3 3 0 LMP repeated region FNIP PF05725.12 EGC36365.1 - 1.5e-155 505.2 63.7 1.5e-15 57.1 0.1 12.0 8 2 4 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.13 EGC36365.1 - 7.1e-07 29.6 0.0 31 5.0 0.0 7.0 5 4 2 7 7 7 2 Phage minor tail protein RNase_T PF00929.24 EGC36366.1 - 0.00052 20.6 0.0 0.00068 20.2 0.0 1.2 1 0 0 1 1 1 1 Exonuclease Acyl_transf_1 PF00698.21 EGC36367.1 - 3.4e-41 141.8 0.0 5.9e-41 141.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.26 EGC36367.1 - 9.8e-40 136.7 0.1 1e-36 126.8 0.0 2.4 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC36367.1 - 6.4e-30 103.6 0.0 1.1e-29 102.8 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC36367.1 - 8.7e-23 81.1 0.0 2e-22 79.9 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC36367.1 - 2.1e-22 79.7 0.0 2.1e-22 79.7 0.0 4.3 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC36367.1 - 9.5e-20 71.0 0.0 1.4e-19 70.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC36367.1 - 8e-17 61.7 0.8 2.7e-16 60.0 0.2 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC36367.1 - 8.3e-10 39.8 0.0 2.5e-09 38.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC36367.1 - 1.5e-06 28.0 0.1 3.4e-06 26.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC36367.1 - 7.7e-06 26.5 0.0 5e-05 23.9 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGC36367.1 - 6.8e-05 23.1 0.1 0.00018 21.8 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC36367.1 - 0.00023 20.6 0.4 0.00052 19.5 0.1 1.7 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC36367.1 - 0.00049 20.0 0.0 0.0013 18.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_28 PF02636.17 EGC36367.1 - 0.031 13.9 0.0 0.23 11.1 0.0 2.3 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_31 PF13847.6 EGC36367.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.9 4 0 0 4 4 3 0 Methyltransferase domain DUF1430 PF07242.11 EGC36367.1 - 0.42 10.9 5.8 0.14 12.4 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) TRADD_N PF09034.10 EGC36367.1 - 0.49 10.5 2.6 1.8 8.7 0.1 3.0 3 0 0 3 3 3 0 TRADD, N-terminal domain adh_short PF00106.25 EGC36368.1 - 1.9e-41 141.7 0.0 2.5e-41 141.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36368.1 - 4.9e-23 81.9 0.0 6.3e-23 81.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36368.1 - 4.5e-05 23.4 0.0 6.6e-05 22.9 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC36368.1 - 9.3e-05 21.7 0.0 0.00015 21.0 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.6 EGC36368.1 - 0.03 14.2 0.0 0.04 13.8 0.0 1.2 1 0 0 1 1 1 0 NAD(P)H-binding 3HCDH_N PF02737.18 EGC36368.1 - 0.033 14.1 0.3 0.14 12.0 0.0 2.0 2 1 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DUF3236 PF11576.8 EGC36368.1 - 0.04 13.6 0.0 0.07 12.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) Epimerase PF01370.21 EGC36368.1 - 0.057 12.9 0.0 0.17 11.3 0.0 1.7 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Glyco_hydro_18 PF00704.28 EGC36369.1 - 8.6e-58 196.5 0.1 1.2e-57 196.1 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Helicase_C PF00271.31 EGC36370.1 - 2.6e-18 66.4 0.0 6.5e-18 65.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain zf-RING_UBOX PF13445.6 EGC36370.1 - 1.1e-09 38.2 6.8 1.4e-08 34.6 3.3 2.7 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC36370.1 - 1e-08 34.8 8.9 1.1e-08 34.8 3.4 2.9 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC36370.1 - 6.9e-07 29.3 7.0 2.5e-06 27.5 3.8 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.25 EGC36370.1 - 9.9e-07 28.5 8.4 1.8e-06 27.7 5.0 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC36370.1 - 1.1e-06 28.4 6.6 1.2e-05 25.1 3.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC36370.1 - 1.4e-06 28.0 6.7 1.1e-05 25.2 2.4 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36370.1 - 2.4e-06 27.8 6.5 1.6e-05 25.1 3.8 2.6 2 0 0 2 2 2 1 Ring finger domain Prok-RING_4 PF14447.6 EGC36370.1 - 0.00012 21.8 5.6 0.0039 17.0 2.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.6 EGC36370.1 - 0.025 14.4 1.1 0.094 12.6 1.1 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zinc-ribbons_6 PF07191.12 EGC36370.1 - 0.17 11.9 2.8 2.2 8.3 1.0 2.4 2 0 0 2 2 2 0 zinc-ribbons zf-RING_10 PF16685.5 EGC36370.1 - 0.27 11.4 3.8 0.36 11.0 1.1 2.4 2 0 0 2 2 2 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EGC36370.1 - 3.1 8.2 6.9 1.5 9.1 1.0 2.9 3 0 0 3 3 2 0 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGC36370.1 - 7 6.5 12.8 1.9 8.3 6.4 2.9 3 0 0 3 3 3 0 RING-like zinc finger SNF2_N PF00176.23 EGC36371.1 - 3.6e-50 170.6 0.1 4e-50 170.5 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.29 EGC36371.1 - 1e-05 25.3 0.0 2.1e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.15 EGC36371.1 - 0.00011 22.2 0.0 0.00014 21.9 0.0 1.1 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S11 PF00411.19 EGC36372.1 - 3.5e-43 146.5 1.6 4.6e-43 146.1 1.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Aa_trans PF01490.18 EGC36373.1 - 4.6e-17 61.8 34.6 1.2e-16 60.5 34.6 1.8 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein NS3_envE PF02723.14 EGC36373.1 - 0.32 11.1 10.2 24 5.1 0.5 4.4 3 1 1 4 4 4 0 Non-structural protein NS3/Small envelope protein E E1-E2_ATPase PF00122.20 EGC36373.1 - 2.5 7.6 7.5 0.26 10.8 0.3 2.7 2 1 0 2 2 2 0 E1-E2 ATPase Mob1_phocein PF03637.17 EGC36374.1 - 3.6e-79 264.7 0.1 4.4e-79 264.4 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family ThiF PF00899.21 EGC36376.1 - 1.4e-49 168.7 0.0 2.1e-49 168.1 0.0 1.2 1 0 0 1 1 1 1 ThiF family 2-Hacid_dh_C PF02826.19 EGC36376.1 - 0.00042 19.7 0.0 0.00068 19.0 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.14 EGC36376.1 - 0.0021 17.6 0.5 0.0035 16.9 0.1 1.6 2 0 0 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TrkA_N PF02254.18 EGC36376.1 - 0.0035 17.6 0.0 0.02 15.2 0.0 2.1 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.16 EGC36376.1 - 0.012 15.2 0.3 0.029 14.0 0.1 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA PglD_N PF17836.1 EGC36376.1 - 0.034 14.8 0.1 0.11 13.2 0.1 1.9 1 0 0 1 1 1 0 PglD N-terminal domain HemeBinding_Shp PF11545.8 EGC36376.1 - 0.039 13.9 0.0 0.078 13.0 0.0 1.6 1 0 0 1 1 1 0 Cell surface heme-binding protein Shp Sacchrp_dh_NADP PF03435.18 EGC36376.1 - 0.059 13.6 1.2 0.2 11.9 1.2 2.0 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain LRR_4 PF12799.7 EGC36377.1 - 2.7e-17 62.6 89.4 0.0044 17.4 5.4 11.8 9 4 4 13 13 13 10 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC36377.1 - 8.6e-17 61.2 34.3 2.5e-06 27.1 3.4 6.6 6 1 0 6 6 6 6 Leucine-rich repeat LRR_8 PF13855.6 EGC36377.1 - 1.8e-16 59.6 60.2 0.00099 18.8 2.1 9.2 6 4 3 10 10 10 9 Leucine rich repeat LRR_6 PF13516.6 EGC36377.1 - 0.056 13.5 41.6 4.7 7.5 0.2 12.3 12 1 1 13 13 13 0 Leucine Rich repeat DUF1729 PF08354.10 EGC36377.1 - 0.084 11.8 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1729) zf-RING_2 PF13639.6 EGC36378.1 - 8.1e-09 35.7 12.7 8.1e-09 35.7 12.7 2.2 2 0 0 2 2 2 1 Ring finger domain TFIIA PF03153.13 EGC36378.1 - 1.3e-08 35.3 36.1 1.3e-08 35.3 36.1 2.3 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_3 PF13920.6 EGC36378.1 - 1e-06 28.5 9.1 2.2e-06 27.4 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC36378.1 - 7.6e-06 26.1 8.0 7.6e-06 26.1 8.0 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC36378.1 - 1.6e-05 24.6 11.4 1.6e-05 24.6 11.4 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC36378.1 - 0.00027 20.8 14.0 0.00027 20.8 14.0 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC36378.1 - 0.0052 16.9 6.1 0.013 15.6 6.1 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_5 PF14634.6 EGC36378.1 - 0.012 15.6 12.3 0.012 15.6 12.3 2.1 3 0 0 3 3 3 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC36378.1 - 0.04 14.1 13.4 0.12 12.5 13.4 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC36378.1 - 0.23 11.3 12.9 0.068 13.0 9.2 2.1 2 1 0 2 2 2 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC36378.1 - 0.58 10.2 5.3 1.6 8.8 5.3 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC36378.1 - 1.4 8.8 10.7 4.9 7.0 10.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EGC36378.1 - 1.4 9.0 11.8 3.8 7.6 10.7 2.4 2 0 0 2 2 2 0 RING-type zinc-finger AAA_23 PF13476.6 EGC36378.1 - 2.4 8.6 34.4 0.41 11.1 10.8 3.4 3 0 0 3 3 3 0 AAA domain Zn_ribbon_17 PF17120.5 EGC36378.1 - 4.8 6.9 9.1 9 6.0 9.1 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_11 PF17123.5 EGC36378.1 - 6.8 6.5 12.2 7.1 6.5 9.5 2.3 2 0 0 2 2 2 0 RING-like zinc finger Dapper PF15268.6 EGC36379.1 - 0.73 8.6 7.6 0.94 8.2 7.6 1.1 1 0 0 1 1 1 0 Dapper Presenilin PF01080.17 EGC36379.1 - 3.7 6.2 14.4 6 5.5 14.4 1.3 1 0 0 1 1 1 0 Presenilin SUIM_assoc PF16619.5 EGC36380.1 - 0.00091 19.2 3.1 0.0023 18.0 3.1 1.7 1 0 0 1 1 1 1 Unstructured region C-term to UIM in Ataxin3 DUF2722 PF10846.8 EGC36380.1 - 0.0025 16.8 0.2 0.0038 16.2 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Ank_2 PF12796.7 EGC36380.1 - 0.031 14.9 0.0 0.13 12.9 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) LPD5 PF18799.1 EGC36380.1 - 2.5 8.5 7.9 1.2 9.6 2.1 2.5 2 0 0 2 2 2 0 Large polyvalent protein-associated domain 5 Activator_LAG-3 PF11498.8 EGC36380.1 - 2.7 6.8 17.9 4 6.3 17.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ependymin PF00811.18 EGC36381.1 - 0.027 14.7 0.1 0.053 13.8 0.1 1.5 1 0 0 1 1 1 0 Ependymin FNIP PF05725.12 EGC36382.1 - 9.8e-42 140.9 40.3 2.9e-08 33.7 0.2 9.4 4 3 5 10 10 10 9 FNIP Repeat Nbl1_Borealin_N PF10444.9 EGC36382.1 - 0.13 12.0 0.0 9.1 6.0 0.0 3.4 2 1 1 3 3 3 0 Nbl1 / Borealin N terminal WD40 PF00400.32 EGC36383.1 - 2.8e-83 271.6 74.3 1.2e-08 35.4 0.8 19.5 20 0 0 20 20 19 15 WD domain, G-beta repeat TROVE PF05731.11 EGC36383.1 - 3.1e-80 270.4 4.3 8.4e-74 249.2 4.1 3.4 1 1 1 2 2 2 2 TROVE domain ANAPC4_WD40 PF12894.7 EGC36383.1 - 1.9e-38 130.7 4.8 8.6e-05 22.8 0.0 11.9 6 3 5 11 11 11 7 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 EGC36383.1 - 2.7e-18 66.1 0.0 1.5e-17 63.8 0.0 2.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) WD40_like PF17005.5 EGC36383.1 - 1.8e-15 57.1 17.0 7e-05 22.3 0.9 5.4 5 0 0 5 5 5 4 WD40-like domain eIF2A PF08662.11 EGC36383.1 - 3.8e-11 43.2 14.3 0.055 13.3 0.8 7.2 4 1 3 7 7 7 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGC36383.1 - 2.2e-10 40.0 11.8 0.48 9.3 0.0 9.1 6 2 1 9 9 9 3 WD40 region of Ge1, enhancer of mRNA-decapping protein APAF1_C PF17908.1 EGC36383.1 - 2.3e-10 40.6 1.1 1.5e-08 34.8 1.1 2.8 1 1 0 1 1 1 1 APAF-1 helical domain AAA_16 PF13191.6 EGC36383.1 - 1.3e-08 35.5 0.0 4.4e-08 33.7 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC36383.1 - 1.6e-06 28.4 0.0 1.8e-05 25.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain NACHT PF05729.12 EGC36383.1 - 1.2e-05 25.3 0.1 3.8e-05 23.7 0.1 1.9 1 1 0 1 1 1 1 NACHT domain PD40 PF07676.12 EGC36383.1 - 0.00025 20.9 2.6 6.7 6.8 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat AAA PF00004.29 EGC36383.1 - 0.002 18.6 0.5 0.079 13.4 0.2 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGC36383.1 - 0.0022 18.0 0.7 0.011 15.7 0.2 2.4 2 0 0 2 2 1 1 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGC36383.1 - 0.02 15.4 0.1 0.099 13.2 0.1 2.3 1 0 0 1 1 1 0 ABC transporter RNA_helicase PF00910.22 EGC36383.1 - 0.033 14.6 0.0 0.23 11.8 0.0 2.6 1 0 0 1 1 1 0 RNA helicase Med9 PF07544.13 EGC36383.1 - 0.071 13.2 1.0 0.41 10.8 1.0 2.3 1 0 0 1 1 1 0 RNA polymerase II transcription mediator complex subunit 9 AAA_7 PF12775.7 EGC36383.1 - 0.12 11.8 0.3 0.55 9.7 0.1 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region TniB PF05621.11 EGC36383.1 - 0.14 11.5 0.0 0.43 10.0 0.0 1.8 1 0 0 1 1 1 0 Bacterial TniB protein DEAD PF00270.29 EGC36384.1 - 3.2e-46 157.3 0.0 1.8e-45 154.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC36384.1 - 6.1e-30 103.8 0.0 1.1e-28 99.7 0.1 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36384.1 - 9.7e-10 38.7 0.2 6.2e-08 32.8 0.0 3.1 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit AAA_30 PF13604.6 EGC36384.1 - 0.0045 16.7 0.0 0.025 14.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain CMS1 PF14617.6 EGC36384.1 - 0.024 14.0 0.0 0.024 14.0 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit Ras PF00071.22 EGC36385.1 - 1.8e-59 200.0 0.0 2.1e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC36385.1 - 9e-20 71.1 0.0 1.2e-19 70.7 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC36385.1 - 3e-10 39.8 0.0 3.5e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC36385.1 - 5.5e-07 29.3 0.1 1.4e-06 27.9 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC36385.1 - 0.0012 18.7 0.0 1.8 8.5 0.0 2.3 2 1 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC36385.1 - 0.0097 16.0 0.0 0.015 15.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC36385.1 - 0.094 12.0 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region TPP_enzyme_M PF00205.22 EGC36385.1 - 0.17 11.7 0.0 0.38 10.5 0.0 1.6 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain FNIP PF05725.12 EGC36386.1 - 1e-34 118.4 75.8 1.5e-08 34.6 3.1 11.4 8 3 3 11 11 11 11 FNIP Repeat Fn3_assoc PF13287.6 EGC36386.1 - 0.53 10.5 3.9 2.3 8.4 0.4 2.9 3 0 0 3 3 3 0 Fn3 associated DNA_ligase_A_M PF01068.21 EGC36387.1 - 4.9e-43 147.2 0.0 1.2e-42 145.9 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGC36387.1 - 3e-37 128.6 2.2 3.3e-37 128.5 1.0 1.8 2 0 0 2 2 2 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGC36387.1 - 2e-18 66.8 0.0 5.7e-18 65.3 0.0 1.8 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.26 EGC36387.1 - 5.5e-16 58.7 2.9 1.3e-09 38.3 0.5 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC36387.1 - 2.6e-14 53.4 3.8 1.1e-07 32.1 0.4 3.3 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain DNA_ligase_IV PF11411.8 EGC36387.1 - 6.2e-14 51.8 1.2 1.5e-13 50.6 1.2 1.8 1 0 0 1 1 1 1 DNA ligase IV RNA_ligase PF09414.10 EGC36387.1 - 4.7e-07 30.3 0.0 1.2e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 RNA ligase LIG3_BRCT PF16759.5 EGC36387.1 - 4.7e-06 26.8 0.1 0.037 14.3 0.0 2.6 2 0 0 2 2 2 2 DNA ligase 3 BRCT domain PTCB-BRCT PF12738.7 EGC36387.1 - 4.4e-05 23.3 0.0 0.23 11.5 0.0 2.7 2 0 0 2 2 2 2 twin BRCT domain mRNA_cap_enzyme PF01331.19 EGC36387.1 - 0.0026 17.6 0.1 2 8.2 0.0 3.0 2 0 0 2 2 2 2 mRNA capping enzyme, catalytic domain TEP1_N PF05386.11 EGC36387.1 - 0.19 11.3 0.3 2.4 7.8 0.6 2.2 2 0 0 2 2 2 0 TEP1 N-terminal domain KCNQ2_u3 PF16642.5 EGC36387.1 - 6.5 7.8 6.9 15 6.7 4.5 2.6 2 0 0 2 2 2 0 Unstructured region on Potassium channel subunit alpha KvLQT2 TIG PF01833.24 EGC36388.1 - 9.5e-05 22.4 3.2 9.5e-05 22.4 3.2 4.6 2 1 1 3 3 3 2 IPT/TIG domain adh_short PF00106.25 EGC36389.1 - 1.8e-45 154.8 0.0 2.4e-45 154.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36389.1 - 4.4e-31 108.2 0.0 5.6e-31 107.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36389.1 - 1.4e-08 34.9 0.0 2.2e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC36389.1 - 0.00014 21.3 0.1 0.00068 19.1 0.1 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGC36389.1 - 0.00021 21.3 0.0 0.00026 20.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGC36389.1 - 0.00024 20.3 0.0 0.00038 19.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC36389.1 - 0.0031 16.7 0.0 0.0039 16.4 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.21 EGC36389.1 - 0.0053 16.3 0.0 0.0086 15.6 0.0 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Gamma_PGA_hydro PF05908.11 EGC36389.1 - 0.091 12.2 0.2 2.9 7.3 0.0 2.3 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase TraC_F_IV PF11130.8 EGC36389.1 - 0.16 11.6 0.0 0.31 10.6 0.0 1.4 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer WD-3 PF09765.9 EGC36390.1 - 4.6e-50 170.6 8.6 3.8e-48 164.3 8.6 2.4 1 1 0 1 1 1 1 WD-repeat region FANCL_C PF11793.8 EGC36390.1 - 1.3e-23 82.9 4.0 3.6e-23 81.5 4.0 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.7 EGC36390.1 - 0.00034 20.8 5.8 0.00082 19.6 5.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC36390.1 - 0.0056 17.0 11.7 0.0089 16.3 8.6 2.7 2 1 0 2 2 2 1 Ring finger domain zf-ANAPC11 PF12861.7 EGC36390.1 - 0.16 12.0 2.8 0.56 10.3 2.8 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atg8 PF02991.16 EGC36392.1 - 3.8e-41 139.5 0.2 4.5e-41 139.3 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGC36392.1 - 8.4e-07 29.3 0.0 1.1e-06 28.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 AA_permease_2 PF13520.6 EGC36393.1 - 4.5e-37 127.9 49.9 5.6e-37 127.6 49.9 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC36393.1 - 2.6e-21 75.8 44.1 3.9e-21 75.2 44.1 1.2 1 0 0 1 1 1 1 Amino acid permease Tetraspanin PF00335.20 EGC36394.1 - 0.33 10.6 14.4 1.2 8.8 14.4 1.9 1 1 0 1 1 1 0 Tetraspanin family Acetyltransf_CG PF14542.6 EGC36396.1 - 1.7e-18 66.5 0.0 2e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Apolipoprotein PF01442.18 EGC36397.1 - 6.7e-07 29.4 16.8 0.0035 17.2 8.7 2.3 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EGC36397.1 - 1.7e-06 28.4 49.4 0.0083 16.6 7.9 6.3 2 1 2 5 5 5 2 YtxH-like protein DUF883 PF05957.13 EGC36397.1 - 4e-06 27.3 19.7 0.089 13.4 0.3 4.8 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) ATP-synt_B PF00430.18 EGC36397.1 - 4.6e-05 23.5 26.6 0.049 13.7 1.5 4.7 1 1 2 4 4 4 4 ATP synthase B/B' CF(0) Phasin PF05597.11 EGC36397.1 - 6.2e-05 23.0 25.9 0.0015 18.5 6.1 4.1 1 1 3 4 4 4 3 Poly(hydroxyalcanoate) granule associated protein (phasin) Focal_AT PF03623.13 EGC36397.1 - 0.0019 18.2 0.6 0.0019 18.2 0.6 2.6 1 1 1 3 3 3 1 Focal adhesion targeting region ApoLp-III PF07464.11 EGC36397.1 - 0.054 13.6 25.8 1.4 9.0 1.1 3.5 1 1 2 3 3 3 0 Apolipophorin-III precursor (apoLp-III) RGS PF00615.19 EGC36397.1 - 1.1 9.5 11.3 0.25 11.6 5.8 2.4 1 1 1 2 2 2 0 Regulator of G protein signaling domain Hormone_1 PF00103.20 EGC36397.1 - 1.2 8.9 9.2 0.72 9.6 2.8 3.0 1 1 2 3 3 3 0 Somatotropin hormone family DivIVA PF05103.13 EGC36397.1 - 3.8 7.6 30.1 3.4 7.7 2.5 4.5 2 1 2 4 4 4 0 DivIVA protein V-ATPase_G_2 PF16999.5 EGC36397.1 - 4.7 7.7 23.0 5.4 7.5 3.9 4.4 2 1 2 4 4 4 0 Vacuolar (H+)-ATPase G subunit Sec23_trunk PF04811.15 EGC36397.1 - 5.5 6.5 6.6 3.7 7.0 0.5 2.3 1 1 1 2 2 2 0 Sec23/Sec24 trunk domain Mitofilin PF09731.9 EGC36397.1 - 6 5.6 33.5 2.7 6.7 13.6 2.0 1 1 1 2 2 2 0 Mitochondrial inner membrane protein Cep57_MT_bd PF06657.13 EGC36398.1 - 0.00066 20.1 0.2 1.2 9.6 0.0 4.0 4 0 0 4 4 4 1 Centrosome microtubule-binding domain of Cep57 DUF3298 PF11738.8 EGC36398.1 - 0.086 13.9 3.6 7.6 7.7 0.0 4.2 4 1 0 4 4 4 0 Protein of unknown function (DUF3298) DUF4252 PF14060.6 EGC36398.1 - 0.81 9.6 6.4 1.4 8.8 0.2 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4252) Inhibitor_I53 PF11714.8 EGC36398.1 - 0.93 9.7 3.0 48 4.3 0.0 3.3 4 0 0 4 4 4 0 Thrombin inhibitor Madanin Alpha-2-MRAP_C PF06401.11 EGC36398.1 - 1 9.3 4.8 26 4.7 0.0 3.5 4 0 0 4 4 4 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3417 PF11897.8 EGC36398.1 - 1.7 9.2 6.4 27 5.3 0.0 4.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3417) Peptidase_S74 PF13884.6 EGC36398.1 - 5 7.5 11.2 26 5.2 0.2 4.2 5 0 0 5 5 5 0 Chaperone of endosialidase His_Phos_1 PF00300.22 EGC36400.1 - 1.5e-14 54.1 0.0 4.5e-12 46.1 0.0 2.1 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) DIOX_N PF14226.6 EGC36401.1 - 4.4e-22 79.0 0.1 8.9e-22 78.1 0.1 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC36401.1 - 6.2e-21 74.8 0.0 1.2e-20 73.9 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3258 PF11646.8 EGC36401.1 - 0.14 12.3 1.1 0.81 9.9 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function DUF3258 FNIP PF05725.12 EGC36402.1 - 1e-32 112.0 11.4 1.1e-08 35.1 0.4 5.7 3 1 2 5 5 5 5 FNIP Repeat eIF3_N PF09440.10 EGC36403.1 - 2.7e-19 69.9 4.8 2.7e-19 69.9 4.8 2.5 2 1 0 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.27 EGC36403.1 - 7e-13 49.0 0.3 2.6e-12 47.1 0.3 1.9 1 0 0 1 1 1 1 PCI domain SURF6 PF04935.12 EGC36403.1 - 0.00071 19.4 1.3 0.00071 19.4 1.3 2.5 2 0 0 2 2 2 1 Surfeit locus protein 6 Mucin PF01456.17 EGC36403.1 - 0.004 17.1 45.7 0.0079 16.2 11.8 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF3439 PF11921.8 EGC36403.1 - 0.028 14.4 32.6 0.092 12.7 9.2 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF2956 PF11169.8 EGC36403.1 - 0.032 14.4 19.6 0.13 12.4 4.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Med3 PF11593.8 EGC36403.1 - 0.11 11.7 23.1 0.16 11.1 7.2 2.2 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Spt20 PF12090.8 EGC36403.1 - 0.29 10.7 21.7 0.95 9.0 9.3 2.3 2 0 0 2 2 2 0 Spt20 family Vfa1 PF08432.10 EGC36403.1 - 0.34 11.2 19.3 0.067 13.5 9.2 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DDHD PF02862.17 EGC36403.1 - 0.75 9.9 11.3 0.43 10.7 1.9 2.4 2 0 0 2 2 2 0 DDHD domain CPSF100_C PF13299.6 EGC36403.1 - 1.5 9.0 17.6 1.6 8.9 6.1 2.3 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal MAP65_ASE1 PF03999.12 EGC36403.1 - 1.5 7.4 19.4 0.84 8.3 8.0 2.5 2 0 0 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) TraV PF09676.10 EGC36403.1 - 1.8 9.5 19.1 0.52 11.3 8.2 2.3 2 0 0 2 2 2 0 Type IV conjugative transfer system lipoprotein (TraV) Rtf2 PF04641.12 EGC36403.1 - 2.5 7.4 14.7 0.56 9.5 6.1 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Peptidase_S49_N PF08496.10 EGC36403.1 - 3.4 7.7 12.0 0.42 10.7 4.5 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal DUF702 PF05142.12 EGC36403.1 - 5.2 7.5 12.8 2.9 8.4 3.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ctr PF04145.15 EGC36403.1 - 7 7.3 8.6 9.7 6.8 1.1 2.5 2 0 0 2 2 2 0 Ctr copper transporter family MRNIP PF15749.5 EGC36403.1 - 7.7 7.3 14.8 2.6 8.8 5.6 2.8 3 0 0 3 3 2 0 MRN-interacting protein TAP_C PF03943.13 EGC36404.1 - 3.8e-05 23.2 0.1 7.3e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 TAP C-terminal domain UBA_4 PF14555.6 EGC36404.1 - 0.0027 17.5 0.0 0.0027 17.5 0.0 2.1 2 1 0 2 2 2 1 UBA-like domain Menin PF05053.13 EGC36404.1 - 0.24 9.7 4.9 0.26 9.6 4.9 1.0 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 EGC36404.1 - 0.61 10.7 11.6 0.84 10.2 11.6 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain APC_u15 PF16636.5 EGC36404.1 - 2.4 8.6 4.8 1.9 9.0 2.9 1.8 1 1 1 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 Peptidase_M64 PF09471.10 EGC36405.1 - 0.011 15.3 0.2 0.027 14.0 0.2 1.6 1 0 0 1 1 1 0 IgA Peptidase M64 Apolipoprotein PF01442.18 EGC36405.1 - 0.017 15.0 5.9 0.017 15.0 5.9 1.7 2 1 0 2 2 2 0 Apolipoprotein A1/A4/E domain Clr5 PF14420.6 EGC36405.1 - 0.29 11.4 0.1 0.29 11.4 0.1 2.9 2 1 1 3 3 3 0 Clr5 domain Peptidase_C26 PF07722.13 EGC36406.1 - 6e-22 78.5 0.0 1.1e-21 77.7 0.0 1.4 1 1 0 1 1 1 1 Peptidase C26 GATase PF00117.28 EGC36406.1 - 8.7e-12 45.2 0.0 1.4e-11 44.6 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Usp PF00582.26 EGC36407.1 - 1.1e-15 58.4 0.0 4.9e-15 56.3 0.0 1.8 1 1 0 1 1 1 1 Universal stress protein family Antimicrobial19 PF08225.11 EGC36407.1 - 0.037 13.6 0.3 0.071 12.7 0.3 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DeoRC PF00455.22 EGC36407.1 - 0.073 13.0 0.0 0.12 12.3 0.0 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain TERB2 PF15101.6 EGC36408.1 - 0.044 13.8 3.3 0.043 13.9 3.3 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 SID-1_RNA_chan PF13965.6 EGC36409.1 - 0.0034 15.9 2.0 0.0041 15.6 2.0 1.1 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 AAA_23 PF13476.6 EGC36409.1 - 0.19 12.2 15.3 0.25 11.8 15.3 1.2 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.9 EGC36409.1 - 0.25 9.6 23.3 0.29 9.3 23.3 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PLDc_N PF13396.6 EGC36409.1 - 1.6 8.8 5.2 2.3 8.2 5.2 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal WD40_4 PF16300.5 EGC36410.1 - 0.026 14.4 0.6 0.057 13.3 0.0 1.9 2 1 0 2 2 2 0 Type of WD40 repeat PEPcase_2 PF14010.6 EGC36411.1 - 0.0096 14.5 2.4 0.014 14.0 2.4 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF3287 PF11690.8 EGC36411.1 - 0.073 12.8 3.4 0.28 10.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3287) SPATIAL PF15256.6 EGC36411.1 - 0.16 12.3 11.2 0.11 12.8 9.7 1.5 1 1 0 1 1 1 0 SPATIAL DUF2852 PF11014.8 EGC36411.1 - 0.68 10.1 5.8 0.33 11.1 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2852) DUF4407 PF14362.6 EGC36411.1 - 2.1 7.6 10.2 2.7 7.3 10.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF5592 PF17332.2 EGC36412.1 - 0.12 12.9 0.0 0.13 12.9 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF5592) adh_short PF00106.25 EGC36413.1 - 3.2e-45 154.0 0.0 3.8e-45 153.8 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36413.1 - 2.8e-44 151.4 0.0 3.6e-44 151.1 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36413.1 - 2e-13 50.7 0.0 2.8e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC36413.1 - 0.0011 18.5 0.1 0.002 17.6 0.1 1.4 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGC36413.1 - 0.0068 15.9 0.0 0.0099 15.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RabGAP-TBC PF00566.18 EGC36414.1 - 3.4e-52 177.2 4.9 4e-52 177.0 0.1 3.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 EGC36414.1 - 2.7e-15 56.2 6.8 4.6e-09 36.2 0.5 2.7 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.8 EGC36414.1 - 0.0026 17.9 0.0 0.014 15.6 0.0 2.3 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 bPH_4 PF06713.11 EGC36414.1 - 0.026 14.6 0.6 0.14 12.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial PH domain bPH_2 PF03703.14 EGC36414.1 - 0.14 12.3 0.1 0.42 10.8 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain Laminin_EGF PF00053.24 EGC36415.1 - 1.6e-09 37.8 89.0 0.016 15.3 15.9 5.6 3 2 2 5 5 5 4 Laminin EGF domain Big_5 PF13205.6 EGC36415.1 - 2.8e-06 28.0 3.5 0.0014 19.3 0.4 3.6 2 0 0 2 2 2 2 Bacterial Ig-like domain DUF4399 PF14347.6 EGC36415.1 - 0.056 13.8 0.1 21 5.6 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4399) EGF_2 PF07974.13 EGC36415.1 - 0.14 12.6 96.0 0.022 15.1 10.7 7.4 6 1 0 6 6 6 0 EGF-like domain Peptidase_S8 PF00082.22 EGC36416.1 - 5.3e-30 104.7 0.5 5.3e-30 104.7 0.5 2.3 3 0 0 3 3 3 1 Subtilase family Baculo_11_kDa PF06143.11 EGC36416.1 - 0.016 14.8 1.2 0.016 14.8 1.2 2.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family Peroxin-13_N PF04088.13 EGC36416.1 - 0.028 14.7 0.3 0.028 14.7 0.3 2.4 3 0 0 3 3 3 0 Peroxin 13, N-terminal region EGF_2 PF07974.13 EGC36416.1 - 0.59 10.5 9.7 0.047 14.1 2.0 2.7 2 1 0 2 2 2 0 EGF-like domain Erf4 PF10256.9 EGC36417.1 - 0.00016 21.8 1.1 0.00034 20.7 0.1 1.9 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF1845 PF08900.11 EGC36417.1 - 0.0011 18.8 1.8 0.0012 18.7 1.8 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1845) YABBY PF04690.13 EGC36417.1 - 0.012 16.1 3.2 0.022 15.3 3.2 1.4 1 0 0 1 1 1 0 YABBY protein DUF2722 PF10846.8 EGC36417.1 - 0.014 14.4 6.9 0.016 14.2 6.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Activator_LAG-3 PF11498.8 EGC36417.1 - 0.043 12.8 15.7 0.055 12.4 15.7 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Glyco_hydro_25 PF01183.20 EGC36419.1 - 7.9e-09 36.0 0.5 9.8e-09 35.6 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 adh_short PF00106.25 EGC36420.1 - 3.3e-39 134.4 0.0 4e-39 134.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36420.1 - 1.6e-17 63.9 0.0 2e-17 63.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36420.1 - 7.8e-08 32.4 0.0 1e-07 32.0 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.15 EGC36420.1 - 0.00011 21.5 0.0 0.00018 20.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RUN PF02759.19 EGC36421.1 - 7.9e-25 87.4 0.2 8e-24 84.1 0.0 3.0 2 0 0 2 2 2 1 RUN domain PH PF00169.29 EGC36421.1 - 0.022 15.2 1.3 0.022 15.2 1.3 2.4 2 0 0 2 2 2 0 PH domain DUF3439 PF11921.8 EGC36421.1 - 0.57 10.1 12.4 2 8.4 12.4 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HEAT_2 PF13646.6 EGC36422.1 - 1.8e-11 44.2 0.2 8e-05 22.9 0.0 3.4 4 0 0 4 4 4 2 HEAT repeats HEAT PF02985.22 EGC36422.1 - 3.5e-11 42.4 0.6 1.1 9.7 0.0 6.7 7 0 0 7 7 7 4 HEAT repeat SUIM_assoc PF16619.5 EGC36422.1 - 2.8e-05 24.1 5.3 2.8e-05 24.1 5.3 7.9 3 1 1 4 4 4 1 Unstructured region C-term to UIM in Ataxin3 DDHD PF02862.17 EGC36422.1 - 0.0013 18.9 32.3 0.18 12.0 15.5 4.1 4 0 0 4 4 4 3 DDHD domain Cnd1 PF12717.7 EGC36422.1 - 0.038 14.0 0.1 0.038 14.0 0.1 6.5 5 1 1 6 6 6 0 non-SMC mitotic condensation complex subunit 1 PP-binding PF00550.25 EGC36423.1 - 8.3e-12 45.3 0.0 1e-11 45.0 0.0 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Chromo PF00385.24 EGC36424.1 - 0.0038 17.1 0.0 0.0064 16.4 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Ring_hydroxyl_B PF00866.18 EGC36424.1 - 0.053 13.6 0.1 0.069 13.2 0.1 1.2 1 0 0 1 1 1 0 Ring hydroxylating beta subunit SOCS PF12610.8 EGC36425.1 - 2.7 8.5 4.1 61 4.1 0.1 3.0 3 0 0 3 3 3 0 Suppressor of cytokine signalling AAT PF03417.16 EGC36426.1 - 2.4e-10 40.5 0.1 2.4e-09 37.2 0.1 2.1 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RAI1 PF08652.11 EGC36427.1 - 6e-16 58.4 1.4 6e-16 58.4 1.4 2.2 2 1 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Rsc14 PF08586.10 EGC36427.1 - 6.2 7.7 7.4 5.1 8.0 1.0 2.6 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit AdoMet_MTase PF07757.13 EGC36428.1 - 3.4e-37 127.2 0.1 7e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.6 EGC36428.1 - 2.4e-05 24.2 1.5 8.5e-05 22.4 0.0 2.5 3 0 0 3 3 3 1 Methyltransferase domain Astro_capsid_p PF12226.8 EGC36428.1 - 0.002 17.4 7.3 0.002 17.4 7.3 2.0 2 0 0 2 2 2 1 Turkey astrovirus capsid protein Methyltransf_11 PF08241.12 EGC36428.1 - 0.0053 17.4 0.0 0.084 13.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MetW PF07021.12 EGC36428.1 - 0.015 14.9 0.1 0.034 13.7 0.1 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.6 EGC36428.1 - 0.056 13.4 0.0 0.056 13.4 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain MTS PF05175.14 EGC36428.1 - 0.095 12.2 0.0 0.17 11.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_25 PF13649.6 EGC36428.1 - 0.14 12.9 0.0 0.38 11.5 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36428.1 - 1.6 9.5 0.0 1.6 9.5 0.0 4.6 5 0 0 5 5 5 0 Methyltransferase domain Mito_carr PF00153.27 EGC36429.1 - 6.3e-68 224.8 2.6 1.9e-26 91.8 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NIF3 PF01784.18 EGC36430.1 - 2.4e-69 233.7 0.1 3.1e-69 233.3 0.1 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) CBS PF00571.28 EGC36431.1 - 6.1e-19 68.2 9.3 1.5e-05 25.4 0.1 4.3 4 0 0 4 4 4 4 CBS domain P4Ha_N PF08336.11 EGC36432.1 - 0.0071 16.4 0.9 0.0071 16.4 0.9 2.4 3 0 0 3 3 3 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TCTP PF00838.17 EGC36432.1 - 0.04 14.3 1.2 0.082 13.3 0.7 1.8 2 0 0 2 2 2 0 Translationally controlled tumour protein DUF2570 PF10828.8 EGC36432.1 - 0.048 13.5 0.3 0.12 12.2 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF2281 PF10047.9 EGC36432.1 - 0.056 14.1 0.2 0.17 12.6 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2281) CLZ PF16526.5 EGC36432.1 - 0.12 12.8 0.2 0.37 11.2 0.2 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Connexin PF00029.19 EGC36433.1 - 0.031 14.0 0.7 0.031 14.0 0.7 2.9 4 0 0 4 4 4 0 Connexin PTPRCAP PF15713.5 EGC36433.1 - 0.035 14.4 1.1 0.049 13.9 1.1 1.1 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TraV PF09676.10 EGC36433.1 - 0.14 13.2 0.9 0.19 12.7 0.9 1.1 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) MASE5 PF17178.4 EGC36433.1 - 0.69 9.7 18.1 2.7 7.8 5.8 2.8 2 2 0 2 2 2 0 Membrane-associated sensor ATP11 PF06644.11 EGC36433.1 - 4.1 7.1 9.2 6.5 6.5 9.2 1.2 1 0 0 1 1 1 0 ATP11 protein DUF805 PF05656.14 EGC36433.1 - 4.4 7.8 8.2 2e+02 2.4 8.2 3.3 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Peptidase_S8 PF00082.22 EGC36434.1 - 1.6e-42 145.8 0.4 1.6e-42 145.8 0.4 2.0 2 1 0 3 3 3 1 Subtilase family EGF_2 PF07974.13 EGC36434.1 - 1.7 9.1 16.2 6.2 7.3 16.2 2.0 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGC36434.1 - 4.3 7.5 11.1 10 6.3 11.1 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Tubulin PF00091.25 EGC36435.1 - 1.9e-68 230.6 0.2 7.6e-68 228.6 0.0 1.9 2 0 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGC36435.1 - 4.2e-42 143.3 0.1 6.9e-42 142.6 0.1 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGC36435.1 - 5.9e-06 26.6 0.0 5.9e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.6 EGC36435.1 - 0.00021 21.0 0.0 0.0005 19.8 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Tubulin_2 PF13809.6 EGC36435.1 - 0.034 13.3 0.0 0.074 12.2 0.0 1.5 1 0 0 1 1 1 0 Tubulin like Tetraspanin PF00335.20 EGC36436.1 - 0.0005 19.8 4.0 0.00062 19.6 4.0 1.3 1 0 0 1 1 1 1 Tetraspanin family Erf4 PF10256.9 EGC36436.1 - 0.0032 17.6 8.1 0.047 13.8 8.1 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family FUN14 PF04930.15 EGC36436.1 - 0.057 13.8 1.1 0.11 12.9 1.1 1.5 1 1 0 1 1 1 0 FUN14 family CactinC_cactus PF09732.9 EGC36436.1 - 0.16 11.9 5.4 0.036 14.0 1.7 1.9 2 1 0 2 2 2 0 Cactus-binding C-terminus of cactin protein DUF2207 PF09972.9 EGC36436.1 - 4.2 6.0 10.0 1.3 7.7 7.0 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Sigma_reg_N PF13800.6 EGC36436.1 - 9.1 6.6 18.3 0.39 11.0 5.1 2.4 1 1 1 2 2 2 0 Sigma factor regulator N-terminal TACC_C PF05010.14 EGC36437.1 - 8e-05 22.5 25.7 0.0024 17.7 4.7 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PspB PF06667.12 EGC36437.1 - 0.24 11.5 3.4 11 6.2 0.1 2.8 2 0 0 2 2 2 0 Phage shock protein B DUF4446 PF14584.6 EGC36437.1 - 5.1 7.1 16.4 3.1 7.8 5.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) p450 PF00067.22 EGC36439.1 - 4.2e-90 302.7 0.5 7e-90 302.0 0.5 1.3 1 1 0 1 1 1 1 Cytochrome P450 DNase_II PF03265.15 EGC36440.1 - 3.1e-32 112.1 4.4 1.6e-18 67.1 0.4 2.3 1 1 0 2 2 2 2 Deoxyribonuclease II Complex1_LYR_2 PF13233.6 EGC36440.1 - 0.11 13.2 0.2 0.43 11.4 0.2 1.9 1 0 0 1 1 1 0 Complex1_LYR-like DUF4228 PF14009.6 EGC36441.1 - 0.04 14.3 1.0 0.048 14.0 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4228) DUF1682 PF07946.14 EGC36441.1 - 0.092 11.9 15.4 0.11 11.7 15.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pex26 PF07163.12 EGC36441.1 - 0.89 8.8 15.9 1.5 8.1 14.7 1.8 1 1 1 2 2 2 0 Pex26 protein SpoIIP PF07454.11 EGC36441.1 - 1.4 8.3 16.9 11 5.4 0.1 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) vATP-synt_E PF01991.18 EGC36441.1 - 1.8 7.9 25.1 0.22 10.9 3.6 2.4 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit Presenilin PF01080.17 EGC36441.1 - 3.6 6.3 8.8 4.5 5.9 8.8 1.2 1 0 0 1 1 1 0 Presenilin DUF4574 PF15141.6 EGC36441.1 - 5.3 7.0 13.7 3.5 7.6 11.6 1.8 2 0 0 2 2 2 0 Ubiquinol-cytochrome-c reductase complex assembly factor 3 Agouti PF05039.12 EGC36441.1 - 7.6 7.3 7.8 15 6.3 7.8 1.5 1 0 0 1 1 1 0 Agouti protein FNIP PF05725.12 EGC36442.1 - 2.4e-128 418.1 93.3 1.2e-15 57.4 1.2 12.6 8 3 3 13 13 13 12 FNIP Repeat Nrap_D5 PF17406.2 EGC36442.1 - 0.16 11.8 0.0 9.3 6.0 0.0 3.0 3 0 0 3 3 3 0 Nrap protein PAP/OAS1-like domain 5 CLU PF13236.6 EGC36444.1 - 1.3e-61 208.3 0.0 3.4e-61 206.9 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC36444.1 - 5.1e-07 29.9 1.3 3.3e-06 27.2 0.0 2.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 XisH PF08814.10 EGC36445.1 - 0.0044 17.2 0.4 0.0055 16.9 0.4 1.1 1 0 0 1 1 1 1 XisH protein FNIP_M PF14637.6 EGC36446.1 - 0.14 12.1 0.0 0.21 11.6 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DDE_3 PF13358.6 EGC36448.1 - 0.019 14.7 0.1 0.027 14.2 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease NYD-SP28 PF14772.6 EGC36448.1 - 0.023 14.7 0.1 0.027 14.5 0.1 1.0 1 0 0 1 1 1 0 Sperm tail Endonuclease_NS PF01223.23 EGC36449.1 - 0.0012 18.7 0.3 0.0026 17.6 0.3 1.5 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease Tir_receptor_C PF07489.11 EGC36449.1 - 3 7.8 10.9 7.2 6.5 10.9 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus HTH_29 PF13551.6 EGC36450.1 - 0.00013 21.9 0.1 0.00018 21.4 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EGC36450.1 - 0.0018 18.1 0.0 0.0031 17.3 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGC36450.1 - 0.028 14.6 0.0 0.045 13.9 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix domain HTH_36 PF13730.6 EGC36450.1 - 0.1 12.6 0.1 0.15 12.0 0.1 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EGC36450.1 - 0.11 12.4 0.0 0.14 12.1 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PAX PF00292.18 EGC36450.1 - 0.11 12.4 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain tRNA-synt_1b PF00579.25 EGC36450.1 - 0.14 11.5 0.0 0.16 11.3 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Coatomer_WDAD PF04053.14 EGC36451.1 - 1.2e-09 37.7 6.1 0.018 14.1 0.0 4.3 4 0 0 4 4 4 4 Coatomer WD associated region WD40 PF00400.32 EGC36451.1 - 9e-07 29.5 0.0 0.064 14.2 0.0 4.9 4 0 0 4 4 4 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36451.1 - 0.021 15.1 0.6 2 8.8 0.1 3.9 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain AA_permease_2 PF13520.6 EGC36452.1 - 1.1e-29 103.6 56.0 1.4e-29 103.3 56.0 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC36452.1 - 2e-24 86.0 51.7 3.2e-24 85.4 51.7 1.2 1 0 0 1 1 1 1 Amino acid permease DUF4271 PF14093.6 EGC36452.1 - 1.7 8.6 36.7 2.8 7.8 17.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4271) ubiquitin PF00240.23 EGC36453.1 - 3.8e-148 481.5 32.1 1.1e-32 111.6 0.6 6.0 5 1 1 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.8 EGC36453.1 - 4.7e-65 215.4 26.5 7.7e-15 54.5 0.6 6.0 5 1 1 6 6 6 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC36453.1 - 3.4e-24 85.1 12.7 0.00087 19.7 0.1 6.8 5 4 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC36453.1 - 2.3e-14 53.1 4.1 0.078 12.9 0.0 4.4 4 0 0 4 4 4 4 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC36453.1 - 6.7e-14 52.0 9.5 0.039 14.3 0.1 4.4 4 1 0 4 4 4 4 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC36453.1 - 7.6e-13 48.5 4.0 0.27 11.3 0.0 5.4 5 3 0 5 5 5 4 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC36453.1 - 3.9e-12 46.7 2.4 0.21 12.1 0.1 4.3 2 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EGC36453.1 - 1.4e-07 31.1 3.5 2.2 7.6 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Big_3_3 PF13750.6 EGC36453.1 - 1.1e-06 28.4 0.3 26 4.5 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Ubiquitin_4 PF18036.1 EGC36453.1 - 1.2e-06 28.4 27.9 25 5.0 0.3 9.6 9 1 1 10 10 10 0 Ubiquitin-like domain DUF2870 PF11069.8 EGC36453.1 - 1.1e-05 25.7 0.0 37 4.8 0.0 5.0 4 0 0 4 4 4 0 Protein of unknown function (DUF2870) DUF2170 PF09938.9 EGC36453.1 - 1.3e-05 25.0 0.8 1.2 8.9 0.1 4.2 4 0 0 4 4 4 1 Uncharacterized protein conserved in bacteria (DUF2170) UDP-g_GGTase PF06427.11 EGC36453.1 - 4.6e-05 23.5 7.7 9 6.5 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase Big_7 PF17957.1 EGC36453.1 - 6.7e-05 23.6 1.1 99 3.8 0.1 5.0 5 0 0 5 5 5 0 Bacterial Ig domain DUF969 PF06149.12 EGC36453.1 - 0.00032 20.2 0.0 25 4.2 0.0 4.4 5 0 0 5 5 5 0 Protein of unknown function (DUF969) ACT_5 PF13710.6 EGC36453.1 - 0.00036 20.3 5.7 53 3.8 0.0 5.2 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 EGC36453.1 - 0.00041 20.4 1.8 1.2e+02 3.0 0.0 6.4 10 0 0 10 10 5 0 ORF11CD3 domain DUF3861 PF12977.7 EGC36453.1 - 0.00045 20.3 3.8 44 4.3 0.0 4.8 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) DUF3435 PF11917.8 EGC36453.1 - 0.00081 18.4 0.5 27 3.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) YcgR_2 PF12945.7 EGC36453.1 - 0.0012 18.9 13.4 8.7 6.6 0.2 5.2 4 1 1 5 5 5 0 Flagellar protein YcgR PDGLE PF13190.6 EGC36453.1 - 0.0015 18.3 7.2 3.8 7.5 0.1 5.3 1 1 4 5 5 5 1 PDGLE domain Corona_NS2A PF05213.12 EGC36453.1 - 0.0029 17.0 0.1 50 3.1 0.0 4.0 4 0 0 4 4 4 0 Coronavirus NS2A protein Imm12 PF15560.6 EGC36453.1 - 0.0068 16.4 5.2 95 2.9 0.0 4.9 5 0 0 5 5 5 0 Immunity protein 12 NEAT PF05031.12 EGC36453.1 - 0.029 15.0 10.7 7.7 7.2 1.9 4.3 1 1 2 3 3 3 0 Iron Transport-associated domain Glyco_tran_WecB PF03808.13 EGC36453.1 - 0.13 12.2 0.0 2.3e+02 1.6 0.0 4.2 4 1 1 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family Plexin_cytopl PF08337.12 EGC36453.1 - 3.9 6.0 16.1 9.1 4.8 0.2 5.4 2 1 2 5 5 5 0 Plexin cytoplasmic RasGAP domain Coiled PF05710.12 EGC36454.1 - 6.6e-07 30.1 35.6 7.2e-07 29.9 24.5 2.3 1 1 1 2 2 2 1 Coiled coil UBX PF00789.20 EGC36455.1 - 1.5e-14 54.0 0.1 4e-14 52.6 0.1 1.8 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.6 EGC36455.1 - 0.0045 17.1 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Thioredoxin-like InvH PF04741.12 EGC36455.1 - 0.02 14.8 0.8 0.049 13.6 0.8 1.7 1 1 0 1 1 1 0 InvH outer membrane lipoprotein Casc1_N PF15927.5 EGC36455.1 - 0.28 10.8 15.9 0.51 10.0 15.9 1.4 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 N-terminus TIG PF01833.24 EGC36456.1 - 4.9e-62 206.0 90.1 5.1e-10 39.3 0.6 15.2 14 1 0 14 14 14 12 IPT/TIG domain TIG PF01833.24 EGC36457.1 - 1.5e-26 92.3 41.7 7.1e-10 38.8 2.0 6.3 6 0 0 6 6 6 4 IPT/TIG domain PRKCSH_1 PF13015.6 EGC36457.1 - 3e-06 27.0 7.1 0.017 14.8 0.3 4.3 3 1 1 4 4 4 2 Glucosidase II beta subunit-like protein FNIP PF05725.12 EGC36458.1 - 3.5e-101 331.2 95.7 8.3e-13 48.3 1.3 10.7 6 1 7 13 13 13 13 FNIP Repeat Syntaxin_2 PF14523.6 EGC36458.1 - 0.07 13.5 1.5 15 6.0 0.2 2.7 3 0 0 3 3 3 0 Syntaxin-like protein Acetyltransf_1 PF00583.25 EGC36459.1 - 2.2e-12 47.2 0.0 2.8e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC36459.1 - 2.6e-10 40.3 0.0 3.2e-10 40.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC36459.1 - 6.3e-10 39.3 0.0 9.1e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC36459.1 - 2.9e-05 24.0 0.0 3.9e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EGC36459.1 - 3.5e-05 23.4 0.2 4.1e-05 23.1 0.2 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGC36459.1 - 0.00063 19.8 0.0 0.00089 19.3 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.7 EGC36459.1 - 0.0021 18.1 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC36459.1 - 0.007 16.5 0.0 0.0096 16.1 0.0 1.2 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC36459.1 - 0.017 15.8 0.0 0.02 15.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PanZ PF12568.8 EGC36459.1 - 0.051 13.3 0.0 0.063 13.0 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ Acetyltransf_13 PF13880.6 EGC36459.1 - 0.11 12.5 0.0 0.17 11.9 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase TFIIE_beta PF02186.15 EGC36460.1 - 1.7e-13 50.6 0.8 7.2e-13 48.6 0.1 2.4 2 0 0 2 2 2 1 TFIIE beta subunit core domain TFA2_Winged_2 PF18121.1 EGC36460.1 - 1.4e-12 47.1 0.1 1.5e-11 43.8 0.1 2.5 3 0 0 3 3 3 1 TFA2 Winged helix domain 2 Peptidase_S8_N PF16361.5 EGC36460.1 - 0.31 11.5 4.9 0.074 13.5 0.7 1.9 2 0 0 2 2 2 0 N-terminal of Subtilase family DUF2250 PF10007.9 EGC36460.1 - 1 9.5 5.1 5 7.3 0.7 3.0 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) U1snRNP70_N PF12220.8 EGC36460.1 - 3 8.5 6.3 0.54 10.9 0.5 2.7 3 1 1 4 4 4 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Acetyltransf_10 PF13673.7 EGC36461.1 - 4.1e-10 39.7 0.0 5.9e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC36461.1 - 2.4e-08 34.2 0.0 2.9e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC36461.1 - 1.8e-07 31.5 0.0 2.7e-07 30.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC36461.1 - 0.00055 20.1 0.0 0.00068 19.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_15 PF17013.5 EGC36461.1 - 0.0044 16.5 0.1 0.0097 15.4 0.1 1.4 1 1 0 1 1 1 1 Putative acetyl-transferase Glyco_hydro_cc PF11790.8 EGC36461.1 - 0.0076 15.8 0.0 0.01 15.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core Acetyltransf_9 PF13527.7 EGC36461.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC36461.1 - 0.04 14.0 0.0 0.072 13.2 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase PanZ PF12568.8 EGC36461.1 - 0.064 13.0 0.1 0.083 12.6 0.1 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain, PanZ FR47 PF08445.10 EGC36461.1 - 0.071 13.1 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_3 PF13302.7 EGC36461.1 - 0.11 13.2 0.0 0.18 12.5 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FAT PF02259.23 EGC36462.1 - 5.7e-44 150.8 0.1 2.2e-43 148.8 0.1 2.1 1 0 0 1 1 1 1 FAT domain ACDC PF14733.6 EGC36462.1 - 9 6.7 15.5 4.2 7.8 0.1 6.7 6 0 0 6 6 6 0 AP2-coincident C-terminal WW PF00397.26 EGC36463.1 - 3e-22 78.4 6.4 7.8e-11 41.9 0.9 2.4 2 0 0 2 2 2 2 WW domain C2 PF00168.30 EGC36463.1 - 6.6e-07 29.6 1.7 0.053 13.8 0.1 3.2 3 0 0 3 3 3 2 C2 domain Aminotran_1_2 PF00155.21 EGC36464.1 - 1.1e-76 258.4 0.0 1.7e-76 257.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGC36464.1 - 0.00035 19.7 0.0 0.0016 17.4 0.0 2.0 2 1 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGC36464.1 - 0.0011 17.6 0.0 0.0018 16.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Not1 PF04054.15 EGC36464.1 - 0.0027 16.7 0.0 0.0046 15.9 0.0 1.3 1 0 0 1 1 1 1 CCR4-Not complex component, Not1 DUF1325 PF07039.11 EGC36465.1 - 1.4e-30 106.0 0.1 3.4e-30 104.8 0.1 1.6 1 0 0 1 1 1 1 SGF29 tudor-like domain Tudor_3 PF18115.1 EGC36465.1 - 2e-05 24.3 0.0 5.2e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 DNA repair protein Crb2 Tudor domain DUF4537 PF15057.6 EGC36465.1 - 0.0052 16.8 0.0 0.0088 16.1 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4537) Hid1 PF12722.7 EGC36465.1 - 0.071 11.2 7.6 0.076 11.1 7.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein XRCC4 PF06632.12 EGC36465.1 - 0.089 11.6 15.4 0.16 10.8 15.4 1.3 1 0 0 1 1 1 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4551 PF15087.6 EGC36465.1 - 1.9 7.2 9.0 2.3 6.9 9.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) CCSAP PF15748.5 EGC36465.1 - 2.2 8.4 17.6 3.1 7.9 17.6 1.2 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Complex1_LYR PF05347.15 EGC36466.1 - 0.048 13.7 1.5 0.1 12.7 0.8 1.9 1 1 0 1 1 1 0 Complex 1 protein (LYR family) LOR PF04525.12 EGC36467.1 - 4.4e-16 59.0 2.2 5.9e-16 58.6 2.2 1.2 1 0 0 1 1 1 1 LURP-one-related DUF3986 PF13143.6 EGC36467.1 - 0.25 12.4 4.8 8.8 7.4 0.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3986) AIF-MLS PF14962.6 EGC36467.1 - 0.26 11.2 0.1 0.34 10.9 0.1 1.1 1 0 0 1 1 1 0 Mitochondria Localisation Sequence LOR PF04525.12 EGC36468.1 - 1.2e-06 28.2 2.6 3e-06 27.0 2.6 1.6 1 1 0 1 1 1 1 LURP-one-related LOR PF04525.12 EGC36469.1 - 2.3e-07 30.6 0.3 2.7e-07 30.4 0.3 1.1 1 0 0 1 1 1 1 LURP-one-related Apolipoprotein PF01442.18 EGC36470.1 - 1.6e-12 47.7 14.8 1.9e-07 31.2 7.4 2.5 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain YtxH PF12732.7 EGC36470.1 - 1.5e-09 38.3 39.8 0.018 15.5 10.3 5.1 1 1 4 5 5 5 4 YtxH-like protein DUF883 PF05957.13 EGC36470.1 - 8.1e-08 32.8 21.2 0.00036 21.1 4.0 4.5 1 1 5 6 6 6 5 Bacterial protein of unknown function (DUF883) Prominin PF05478.11 EGC36470.1 - 1.4e-05 23.3 15.3 2.1e-05 22.7 13.3 2.2 1 1 1 2 2 2 1 Prominin ApoLp-III PF07464.11 EGC36470.1 - 0.0014 18.7 25.9 0.095 12.8 11.5 3.0 1 1 1 2 2 2 2 Apolipophorin-III precursor (apoLp-III) MA3 PF02847.17 EGC36470.1 - 0.029 14.3 6.5 1.3 9.0 0.3 3.6 1 1 2 3 3 3 0 MA3 domain Exonuc_VII_L PF02601.15 EGC36470.1 - 0.073 12.6 13.1 0.31 10.6 7.5 2.0 1 1 1 2 2 2 0 Exonuclease VII, large subunit Chlorosome_CsmC PF11098.8 EGC36470.1 - 0.074 13.0 14.4 0.082 12.9 3.7 3.4 1 1 3 4 4 4 0 Chlorosome envelope protein C DUF948 PF06103.11 EGC36470.1 - 0.076 13.3 19.5 5.1 7.4 3.7 4.3 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) PhaP_Bmeg PF09602.10 EGC36470.1 - 0.082 12.8 16.4 0.16 11.9 15.4 2.0 1 1 1 2 2 2 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ApoC-I PF04691.12 EGC36470.1 - 0.083 12.8 18.7 0.15 12.0 0.3 4.8 2 2 2 4 4 4 0 Apolipoprotein C-I (ApoC-1) AAA_32 PF13654.6 EGC36470.1 - 0.093 11.5 16.2 0.18 10.5 4.0 2.1 1 1 1 2 2 2 0 AAA domain WXG100 PF06013.12 EGC36470.1 - 0.15 12.3 18.8 1.7 8.9 5.0 4.0 1 1 3 4 4 4 0 Proteins of 100 residues with WXG RRF PF01765.19 EGC36470.1 - 0.16 11.9 28.6 1 9.3 10.3 3.1 1 1 2 3 3 3 0 Ribosome recycling factor DUF1664 PF07889.12 EGC36470.1 - 0.16 12.0 14.6 8.4 6.4 1.1 3.4 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) p450 PF00067.22 EGC36470.1 - 0.2 10.4 8.3 0.37 9.5 8.2 1.3 1 1 0 1 1 1 0 Cytochrome P450 Tape_meas_lam_C PF09718.10 EGC36470.1 - 0.21 11.8 26.7 0.42 10.8 0.6 5.1 2 2 3 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) CorA PF01544.18 EGC36470.1 - 0.25 10.6 2.9 0.29 10.4 0.9 1.7 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF1640 PF07798.11 EGC36470.1 - 0.34 10.9 15.1 0.76 9.8 14.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) YlqD PF11068.8 EGC36470.1 - 0.87 10.0 13.8 3.6 8.0 4.9 3.1 1 1 1 3 3 3 0 YlqD protein Mobilization_B PF17511.2 EGC36470.1 - 0.91 9.9 12.3 2 8.8 1.0 3.4 1 1 2 3 3 3 0 Mobilization protein B DUF2884 PF11101.8 EGC36470.1 - 0.91 9.0 23.0 2.1 7.8 7.5 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) DUF3584 PF12128.8 EGC36470.1 - 0.93 6.9 22.2 0.21 9.1 10.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF3106 PF11304.8 EGC36470.1 - 1.3 9.6 8.5 2.2 8.8 0.6 2.5 1 1 0 2 2 2 0 Protein of unknown function (DUF3106) OmpH PF03938.14 EGC36470.1 - 1.9 8.9 26.3 2.5 8.4 12.7 2.9 1 1 2 3 3 3 0 Outer membrane protein (OmpH-like) Nup88 PF10168.9 EGC36470.1 - 2.2 6.0 16.5 4 5.1 15.7 1.6 1 1 1 2 2 2 0 Nuclear pore component Baculo_PEP_C PF04513.12 EGC36470.1 - 2.5 8.1 10.1 2.3 8.3 0.9 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.6 EGC36470.1 - 2.9 8.2 24.7 0.61 10.4 7.9 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein EspB PF05802.11 EGC36470.1 - 3.2 7.7 24.9 0.46 10.4 4.1 2.3 1 1 1 2 2 2 0 Enterobacterial EspB protein KMP11 PF03037.16 EGC36470.1 - 3.5 8.5 16.1 1.1 10.0 9.5 2.9 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 Uteroglobin PF01099.17 EGC36470.1 - 4.4 7.7 15.0 2.8 8.4 4.8 3.8 2 1 1 3 3 3 0 Uteroglobin family DUF1451 PF07295.11 EGC36470.1 - 4.7 7.2 18.7 2.4 8.2 7.0 2.5 1 1 0 2 2 2 0 Zinc-ribbon containing domain DUF4175 PF13779.6 EGC36470.1 - 5 4.9 21.1 15 3.4 21.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) PIN_8 PF18476.1 EGC36470.1 - 5.6 6.8 24.3 1.1e+04 -4.0 24.3 2.8 1 1 0 1 1 0 0 PIN like domain V-ATPase_G_2 PF16999.5 EGC36470.1 - 7 7.1 19.8 1.1 9.7 1.5 3.5 1 1 1 3 3 3 0 Vacuolar (H+)-ATPase G subunit G8 PF10162.9 EGC36471.1 - 3.2e-07 30.5 7.3 0.21 11.7 0.1 7.5 3 2 1 5 5 5 2 G8 domain DUF3211 PF11485.8 EGC36471.1 - 0.023 14.9 2.2 0.17 12.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3211) Band_7 PF01145.25 EGC36472.1 - 6.7e-30 104.4 1.5 8e-30 104.2 1.5 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0158 PF03682.13 EGC36472.1 - 0.011 15.7 0.3 0.022 14.8 0.2 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0158) MutS_II PF05188.17 EGC36472.1 - 0.039 14.2 0.2 0.068 13.5 0.2 1.4 1 1 0 1 1 1 0 MutS domain II DUF4904 PF16247.5 EGC36472.1 - 0.072 12.9 0.4 0.43 10.4 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4904) Cation_efflux PF01545.21 EGC36473.1 - 8.3e-27 94.2 11.2 1.1e-26 93.8 11.2 1.1 1 0 0 1 1 1 1 Cation efflux family ZT_dimer PF16916.5 EGC36473.1 - 8.8e-12 45.0 0.0 1.9e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Dimerisation domain of Zinc Transporter NnrS PF05940.12 EGC36473.1 - 0.057 12.8 4.2 0.079 12.3 4.2 1.1 1 0 0 1 1 1 0 NnrS protein Methyltransf_11 PF08241.12 EGC36474.1 - 2.4e-16 60.2 0.0 9.2e-16 58.3 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC36474.1 - 6e-15 55.7 0.0 1.6e-13 51.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36474.1 - 8.3e-10 38.7 0.0 1.9e-09 37.5 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36474.1 - 5.9e-09 36.6 0.1 3.7e-08 34.0 0.0 2.2 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36474.1 - 7.1e-09 35.7 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC36474.1 - 1.5e-07 31.0 0.0 2.4e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_PK PF05891.12 EGC36474.1 - 0.0011 18.5 0.0 0.0018 17.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.20 EGC36474.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 EGC36474.1 - 0.0016 18.4 0.0 0.018 14.9 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase DUF938 PF06080.12 EGC36474.1 - 0.0091 15.8 0.0 0.015 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 EGC36474.1 - 0.01 15.6 0.0 0.033 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGC36474.1 - 0.068 13.3 0.0 0.23 11.6 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase MTS PF05175.14 EGC36474.1 - 0.089 12.3 0.0 0.25 10.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EGC36474.1 - 0.12 11.9 0.0 0.33 10.5 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW CdiI_2 PF18593.1 EGC36474.1 - 0.13 12.9 0.7 0.49 11.1 0.1 2.3 3 0 0 3 3 3 0 CdiI immunity protein zf-TRAF PF02176.18 EGC36475.1 - 9.3e-10 39.1 39.1 6.3e-08 33.2 11.0 5.1 2 2 3 5 5 5 4 TRAF-type zinc finger zf-U11-48K PF05253.12 EGC36475.1 - 0.0013 18.6 1.0 5.8 7.0 0.0 4.0 3 0 0 3 3 3 2 U11-48K-like CHHC zinc finger zf-RING_2 PF13639.6 EGC36475.1 - 0.0018 18.6 10.6 0.0018 18.6 10.6 3.6 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC36475.1 - 0.0029 17.4 12.1 0.0029 17.4 12.1 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC36475.1 - 0.0032 17.3 11.6 0.0032 17.3 11.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC36475.1 - 0.0039 17.6 30.3 0.076 13.5 10.3 3.6 1 1 2 3 3 3 2 TRAF-like zinc-finger Sina PF03145.16 EGC36475.1 - 0.0046 16.9 2.5 0.0046 16.9 2.5 2.9 1 1 1 2 2 2 1 Seven in absentia protein family Csm1_N PF18504.1 EGC36475.1 - 0.038 14.3 2.6 0.084 13.2 2.6 1.6 1 0 0 1 1 1 0 Csm1 N-terminal domain TMF_DNA_bd PF12329.8 EGC36475.1 - 2 8.5 10.3 0.19 11.7 4.9 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding ParA PF10609.9 EGC36476.1 - 4.7e-61 206.4 0.0 5.4e-61 206.2 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase AAA_26 PF13500.6 EGC36476.1 - 0.01 15.7 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain Acetyltransf_2 PF00797.17 EGC36477.1 - 3.3e-09 36.9 0.2 7.8e-09 35.7 0.2 1.5 1 1 0 1 1 1 1 N-acetyltransferase EDR1 PF14381.6 EGC36477.1 - 0.017 14.9 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 BRCT_3 PF18428.1 EGC36478.1 - 4.9e-16 58.7 0.0 1.3e-15 57.3 0.0 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT PF00533.26 EGC36478.1 - 1.4e-12 47.8 0.5 7.4e-05 23.1 0.1 3.3 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC36478.1 - 6.6e-10 39.3 13.2 5.2e-05 23.6 0.2 4.4 4 0 0 4 4 4 2 BRCT domain, a BRCA1 C-terminus domain NAD_binding_10 PF13460.6 EGC36479.1 - 7.1e-12 45.6 0.0 1.1e-11 45.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGC36479.1 - 1.1e-10 41.1 0.0 6.8e-09 35.2 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGC36479.1 - 3.3e-10 39.8 0.0 2.7e-09 36.9 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC36479.1 - 1e-08 34.5 0.1 4.5e-07 29.2 0.1 2.1 1 1 1 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.13 EGC36479.1 - 1.5e-08 34.5 0.0 2.7e-08 33.7 0.0 1.4 1 1 0 1 1 1 1 NmrA-like family NAD_binding_4 PF07993.12 EGC36479.1 - 6.4e-08 32.1 0.6 0.027 13.6 0.0 3.1 2 1 1 3 3 3 3 Male sterility protein GDP_Man_Dehyd PF16363.5 EGC36479.1 - 0.00016 21.2 0.0 0.00028 20.4 0.0 1.4 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGC36479.1 - 0.00045 20.5 0.0 0.00083 19.6 0.0 1.4 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EGC36479.1 - 0.0014 18.2 0.0 0.0022 17.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36479.1 - 0.024 14.2 0.0 0.044 13.3 0.0 1.5 1 1 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase His_Phos_2 PF00328.22 EGC36480.1 - 6.8e-29 101.4 0.6 1.1e-28 100.7 0.0 1.5 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 2) Asn_synthase PF00733.21 EGC36481.1 - 1.2e-95 321.3 0.1 3.2e-56 191.5 0.0 2.1 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.6 EGC36481.1 - 3.3e-43 146.5 0.0 5.5e-43 145.8 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC36481.1 - 3.1e-34 118.0 0.0 5e-34 117.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC36481.1 - 9.4e-15 54.7 0.0 1.6e-14 53.9 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein tRNA_Me_trans PF03054.16 EGC36481.1 - 0.06 12.1 0.0 0.099 11.4 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.17 EGC36481.1 - 0.065 12.3 0.0 0.2 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD synthase DUF1933 PF09147.10 EGC36481.1 - 0.15 11.6 0.0 0.26 10.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Cellulase PF00150.18 EGC36482.1 - 1.2e-28 100.4 0.7 2.4e-28 99.4 0.7 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C9 PF01707.16 EGC36482.1 - 0.049 13.2 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 Peptidase family C9 7tm_1 PF00001.21 EGC36483.1 - 0.059 12.7 3.1 0.28 10.5 3.1 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Orf78 PF06024.12 EGC36483.1 - 0.14 12.5 0.1 0.14 12.5 0.1 3.2 3 1 1 4 4 4 0 Orf78 (ac78) PMT_2 PF13231.6 EGC36483.1 - 0.17 12.1 9.6 0.042 14.1 4.1 2.4 2 0 0 2 2 2 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF2106 PF09879.9 EGC36483.1 - 0.38 10.3 2.6 1.1 8.8 0.1 2.5 3 0 0 3 3 3 0 Predicted membrane protein (DUF2106) DUF4212 PF13937.6 EGC36483.1 - 1.2 9.6 9.7 0.25 11.8 3.7 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4212) Dicty_CTDC PF00526.18 EGC36484.1 - 0.0054 16.6 10.4 0.0054 16.6 10.4 5.7 3 1 0 3 3 3 2 Dictyostelium (slime mold) repeat NUDIX PF00293.28 EGC36485.1 - 1.5e-15 57.4 0.0 3.4e-15 56.2 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain zf-C3HC PF07967.13 EGC36485.1 - 0.059 13.4 0.0 0.19 11.8 0.0 1.8 1 0 0 1 1 1 0 C3HC zinc finger-like Acyl-CoA_dh_1 PF00441.24 EGC36486.1 - 2.2e-28 99.4 0.1 3.9e-28 98.6 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGC36486.1 - 9.2e-28 97.2 0.0 2e-27 96.1 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGC36486.1 - 1.4e-22 79.7 0.3 2.8e-22 78.7 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC36486.1 - 5.8e-06 26.6 0.0 9e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TIG PF01833.24 EGC36487.1 - 1.6e-06 28.1 19.6 0.0003 20.8 4.7 4.5 4 0 0 4 4 4 2 IPT/TIG domain ABC_tran PF00005.27 EGC36488.1 - 1.5e-23 83.8 0.1 7e-15 55.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter MCD PF05292.11 EGC36488.1 - 0.0039 16.8 0.2 0.01 15.5 0.2 1.7 1 0 0 1 1 1 1 Malonyl-CoA decarboxylase C-terminal domain AAA_29 PF13555.6 EGC36488.1 - 0.029 14.1 0.4 0.41 10.4 0.0 2.7 2 0 0 2 2 2 0 P-loop containing region of AAA domain Semialdhyde_dh PF01118.24 EGC36489.1 - 5.8e-25 88.1 0.0 1.4e-24 86.8 0.0 1.7 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.28 EGC36489.1 - 3e-23 82.7 0.6 7.2e-23 81.4 0.0 1.9 3 0 0 3 3 3 1 Amino acid kinase family NAT PF04768.13 EGC36489.1 - 1.5e-12 47.5 6.7 3.3e-12 46.4 6.7 1.5 1 0 0 1 1 1 1 NAT, N-acetyltransferase, of N-acetylglutamate synthase DapB_N PF01113.20 EGC36489.1 - 0.11 12.7 0.0 0.37 10.9 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1803 PF08820.10 EGC36489.1 - 0.27 11.3 3.3 0.21 11.6 0.8 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1803) 7tm_2 PF00002.24 EGC36490.1 - 3.4e-24 85.5 19.0 4.3e-24 85.1 19.0 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.11 EGC36490.1 - 8.8e-20 71.0 24.2 1.1e-19 70.7 24.2 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.15 EGC36490.1 - 4e-10 39.2 5.7 4e-10 39.2 5.7 1.8 2 0 0 2 2 2 1 Ocular albinism type 1 protein Frizzled PF01534.17 EGC36490.1 - 1e-07 31.3 24.5 2.8e-07 29.9 7.4 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region Bac_export_2 PF01312.19 EGC36490.1 - 0.41 9.8 2.6 0.49 9.6 2.3 1.3 1 1 0 1 1 1 0 FlhB HrpN YscU SpaS Family Tim17 PF02466.19 EGC36491.1 - 3.1e-05 24.3 5.1 4.5e-05 23.8 5.1 1.2 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Elf1 PF05129.13 EGC36492.1 - 2.7e-30 104.2 1.7 3e-30 104.1 1.7 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Rubredoxin PF00301.20 EGC36492.1 - 0.0023 17.9 2.1 0.026 14.5 0.3 2.3 2 0 0 2 2 2 1 Rubredoxin zf-Sec23_Sec24 PF04810.15 EGC36492.1 - 0.14 12.2 3.1 1.2 9.2 0.3 2.3 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger Ank_3 PF13606.6 EGC36493.1 - 0.024 15.1 3.8 40 5.2 0.1 5.7 6 0 0 6 6 6 0 Ankyrin repeat DUF1005 PF06219.12 EGC36493.1 - 0.052 12.6 0.1 0.085 11.9 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1005) CRC_subunit PF08624.10 EGC36494.1 - 0.059 13.8 1.1 0.98 9.9 0.1 3.0 2 0 0 2 2 2 0 Chromatin remodelling complex Rsc7/Swp82 subunit Ank_3 PF13606.6 EGC36494.1 - 2 9.3 4.1 95 4.1 0.0 5.8 6 1 1 7 7 7 0 Ankyrin repeat TPR_1 PF00515.28 EGC36495.1 - 2.4e-17 61.9 4.0 0.00064 19.4 0.4 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_2 PF07719.17 EGC36495.1 - 9.9e-17 59.7 5.0 0.00099 19.1 0.0 6.3 7 0 0 7 7 5 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGC36495.1 - 8.5e-16 57.1 12.7 0.00032 20.9 0.3 5.7 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.6 EGC36495.1 - 1.3e-15 56.7 6.5 0.0079 15.9 0.1 5.7 4 1 1 5 5 5 4 TPR repeat TPR_16 PF13432.6 EGC36495.1 - 8e-13 48.8 0.1 6.6e-05 23.5 0.1 3.7 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.6 EGC36495.1 - 3.1e-12 46.2 1.1 0.012 16.4 0.0 6.0 3 2 4 7 7 6 4 Tetratricopeptide repeat TPR_19 PF14559.6 EGC36495.1 - 4e-10 40.1 2.7 0.023 15.2 0.0 4.7 2 2 2 5 5 5 4 Tetratricopeptide repeat TPR_20 PF14561.6 EGC36495.1 - 5.8e-10 39.4 1.3 0.011 16.1 0.0 4.8 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGC36495.1 - 1.9e-06 27.5 3.8 3.2 8.0 0.0 5.6 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC36495.1 - 1.8e-05 24.8 0.4 0.027 14.6 0.0 3.4 3 1 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC36495.1 - 4.9e-05 23.2 11.5 3 8.3 0.0 5.8 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC36495.1 - 0.00024 21.3 8.1 0.093 13.0 0.2 4.1 3 1 2 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC36495.1 - 0.0025 18.0 1.9 0.24 11.6 0.0 2.5 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.6 EGC36495.1 - 0.0038 16.5 0.9 0.35 10.1 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC36495.1 - 0.0049 17.4 1.4 15 6.5 0.1 4.9 5 0 0 5 5 4 0 Tetratricopeptide repeat ChAPs PF09295.10 EGC36495.1 - 0.0066 15.5 3.7 0.18 10.7 0.0 2.8 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) DUF4248 PF14053.6 EGC36495.1 - 0.0074 16.3 1.0 0.041 13.9 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4248) PPTA PF01239.22 EGC36495.1 - 0.02 14.6 1.5 29 4.6 0.1 3.8 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat 6PF2K PF01591.18 EGC36495.1 - 0.056 12.7 0.1 0.14 11.4 0.1 1.6 1 0 0 1 1 1 0 6-phosphofructo-2-kinase BTAD PF03704.17 EGC36495.1 - 0.06 13.8 0.4 1.1 9.7 0.1 2.6 3 0 0 3 3 3 0 Bacterial transcriptional activator domain DUF3439 PF11921.8 EGC36496.1 - 0.19 11.7 7.4 1.3 9.0 0.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) EGF_2 PF07974.13 EGC36498.1 - 0.0011 19.3 10.4 0.0011 19.3 10.4 3.4 2 0 0 2 2 2 1 EGF-like domain OST_IS PF18246.1 EGC36498.1 - 0.1 12.9 1.4 8.8 6.7 0.1 3.4 3 0 0 3 3 3 0 Oligosaccharyltransferase Insert domain SKG6 PF08693.10 EGC36498.1 - 0.63 9.5 4.8 0.7 9.4 2.4 2.3 2 0 0 2 2 2 0 Transmembrane alpha-helix domain VP4_2 PF08935.10 EGC36498.1 - 1.4 9.5 11.6 0.11 13.2 2.6 3.0 2 0 0 2 2 2 0 Viral protein VP4 subunit Spheroidin PF05541.12 EGC36499.1 - 4.1e-05 21.7 7.7 5.1e-05 21.3 7.7 1.1 1 0 0 1 1 1 1 Entomopoxvirus spheroidin protein Peptidase_M16 PF00675.20 EGC36500.1 - 4.5e-21 75.4 0.0 9.9e-21 74.3 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_M PF16187.5 EGC36500.1 - 1e-20 74.2 4.8 1.8e-20 73.4 4.8 1.4 1 0 0 1 1 1 1 Middle or third domain of peptidase_M16 Peptidase_M16_C PF05193.21 EGC36500.1 - 1.3e-13 51.4 0.1 3.8e-13 49.9 0.1 1.8 1 0 0 1 1 1 1 Peptidase M16 inactive domain Chlam_OMP PF01308.17 EGC36501.1 - 0.099 11.4 0.0 0.12 11.1 0.0 1.3 1 0 0 1 1 1 0 Chlamydia major outer membrane protein DUF1387 PF07139.11 EGC36501.1 - 0.24 11.1 4.5 0.33 10.6 4.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Herpes_LAMP2 PF06126.11 EGC36502.1 - 0.053 12.2 0.1 0.059 12.0 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 NDUF_C2 PF06374.11 EGC36504.1 - 0.00087 19.4 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) DUF3973 PF13119.6 EGC36504.1 - 0.032 14.3 0.6 0.032 14.3 0.6 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3973) ATG22 PF11700.8 EGC36504.1 - 0.12 11.0 0.0 0.14 10.7 0.0 1.0 1 0 0 1 1 1 0 Vacuole effluxer Atg22 like Evr1_Alr PF04777.13 EGC36505.1 - 4.7e-29 100.8 0.1 4.7e-29 100.8 0.1 1.8 2 1 0 2 2 2 1 Erv1 / Alr family Bac_surface_Ag PF01103.23 EGC36506.1 - 2.7e-10 40.2 14.8 4.9e-10 39.4 14.8 1.4 1 1 0 1 1 1 1 Surface antigen Helicase_RecD PF05127.14 EGC36506.1 - 0.072 12.9 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase bMG1 PF17970.1 EGC36506.1 - 0.099 12.7 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 Bacterial Alpha-2-macroglobulin MG1 domain Phospholip_B PF04916.13 EGC36508.1 - 1.4e-165 551.9 9.5 1.6e-165 551.7 9.5 1.0 1 0 0 1 1 1 1 Phospholipase B Ependymin PF00811.18 EGC36509.1 - 0.00043 20.5 1.3 0.00088 19.5 1.3 1.5 1 0 0 1 1 1 1 Ependymin FNIP PF05725.12 EGC36510.1 - 7.3e-23 80.5 71.7 1.5e-09 37.9 0.2 12.3 9 3 4 13 13 13 10 FNIP Repeat C2 PF00168.30 EGC36511.1 - 3.5e-08 33.7 0.6 7.1e-08 32.7 0.1 1.8 2 1 0 2 2 2 1 C2 domain Endotoxin_N PF03945.14 EGC36512.1 - 2.7e-06 27.3 1.7 2.7e-06 27.3 1.7 2.2 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain p450 PF00067.22 EGC36514.1 - 5.5e-88 295.7 2.3 6.3e-88 295.5 2.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF4488 PF14869.6 EGC36515.1 - 0.14 12.1 0.0 0.21 11.5 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4488) FNIP PF05725.12 EGC36516.1 - 1.2e-68 227.0 82.5 1e-09 38.4 0.6 13.1 2 2 14 17 17 17 17 FNIP Repeat DUF5541 PF17695.1 EGC36516.1 - 0.2 12.1 0.2 5 7.6 0.0 3.1 2 1 1 3 3 3 0 Family of unknown function (DUF5541) zf-TRAF PF02176.18 EGC36517.1 - 5.7e-13 49.3 31.0 1.1e-10 42.0 8.8 4.6 3 2 2 5 5 5 2 TRAF-type zinc finger Sina PF03145.16 EGC36517.1 - 4.5e-06 26.8 21.5 0.019 14.9 10.4 3.8 3 1 1 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC36517.1 - 5.2e-06 26.2 11.2 5.2e-06 26.2 11.2 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36517.1 - 7e-06 26.3 9.2 7e-06 26.3 9.2 3.1 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC36517.1 - 7.7e-06 25.7 6.6 7.7e-06 25.7 6.6 2.8 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC36517.1 - 2.3e-05 24.5 8.1 2.3e-05 24.5 8.1 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING zf-ACC PF17848.1 EGC36517.1 - 7.7e-05 22.7 7.2 0.2 11.7 0.0 4.2 4 0 0 4 4 4 2 Acetyl-coA carboxylase zinc finger domain zf-RING_UBOX PF13445.6 EGC36517.1 - 0.0003 20.7 6.7 0.00058 19.8 5.0 2.5 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC36517.1 - 0.00044 20.1 10.8 0.00044 20.1 10.8 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC36517.1 - 0.00089 19.4 6.5 0.00089 19.4 6.5 2.6 2 1 0 2 2 1 1 zinc RING finger of MSL2 DUF1272 PF06906.11 EGC36517.1 - 0.013 15.6 3.9 0.013 15.6 3.9 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1272) zf-TRAF_2 PF15965.5 EGC36517.1 - 0.021 15.3 21.4 0.059 13.8 6.6 4.5 3 1 2 5 5 5 0 TRAF-like zinc-finger DUF1003 PF06210.11 EGC36517.1 - 0.19 11.9 0.8 0.35 11.0 0.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Prok-RING_4 PF14447.6 EGC36517.1 - 0.96 9.4 14.6 0.047 13.6 8.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-Di19 PF05605.12 EGC36517.1 - 3.3 8.1 13.7 16 5.9 0.0 4.1 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding DZR PF12773.7 EGC36517.1 - 9.6 6.3 19.0 9 6.4 5.9 2.8 2 0 0 2 2 2 0 Double zinc ribbon tRNA-synt_2 PF00152.20 EGC36518.1 - 4.5e-74 249.3 1.1 6e-74 248.9 1.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGC36518.1 - 5e-06 26.4 0.2 1.2e-05 25.2 0.2 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain 4HB_MCP_1 PF12729.7 EGC36518.1 - 0.0068 16.0 0.6 0.013 15.1 0.6 1.3 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction tRNA-synt_2d PF01409.20 EGC36518.1 - 0.011 15.2 0.5 1.3 8.4 0.0 2.3 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) Pex2_Pex12 PF04757.14 EGC36519.1 - 1.6e-39 135.9 8.3 1.6e-39 135.9 8.3 2.2 2 1 0 2 2 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.25 EGC36519.1 - 3e-06 27.0 12.9 5.6e-06 26.1 12.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC36519.1 - 1.1e-05 25.1 9.1 1.7e-05 24.6 9.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC36519.1 - 2.4e-05 24.2 11.4 4.4e-05 23.4 11.4 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC36519.1 - 4.2e-05 23.3 12.5 7.3e-05 22.5 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36519.1 - 0.00018 21.7 12.3 0.00029 21.1 12.3 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.6 EGC36519.1 - 0.00024 21.2 15.2 0.00041 20.5 15.2 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC36519.1 - 0.00047 20.1 11.2 0.00075 19.4 11.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC36519.1 - 0.014 15.3 12.5 0.35 10.8 13.1 2.2 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf_UBZ PF18439.1 EGC36519.1 - 0.21 11.2 2.2 0.68 9.6 0.1 2.5 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger zf-RING_10 PF16685.5 EGC36519.1 - 0.23 11.6 5.3 0.46 10.7 5.3 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-rbx1 PF12678.7 EGC36519.1 - 0.25 11.7 6.8 0.62 10.4 6.8 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger domain FNIP PF05725.12 EGC36520.1 - 1.6e-06 28.1 25.3 0.15 12.2 0.5 6.4 4 2 2 6 6 6 4 FNIP Repeat Secretin_N_2 PF07655.13 EGC36520.1 - 2.7 8.6 19.6 6.5 7.4 19.6 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.12 EGC36521.1 - 3e-66 219.4 65.6 2.1e-13 50.2 0.1 11.5 7 3 3 12 12 12 9 FNIP Repeat FNIP PF05725.12 EGC36522.1 - 4e-102 334.2 83.9 1.5e-14 53.8 0.9 14.8 2 1 13 17 17 17 16 FNIP Repeat DUF1769 PF08588.10 EGC36522.1 - 0.0011 19.1 2.9 12 6.2 0.0 5.8 5 1 1 6 6 6 1 Protein of unknown function (DUF1769) Barstar PF01337.18 EGC36523.1 - 0.00015 21.7 0.2 0.00029 20.8 0.2 1.7 1 1 0 1 1 1 1 Barstar (barnase inhibitor) DUF4790 PF16037.5 EGC36523.1 - 0.039 14.4 0.3 0.077 13.5 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4790) RVP PF00077.20 EGC36524.1 - 0.012 16.0 0.0 0.027 14.8 0.0 1.6 1 0 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGC36524.1 - 0.012 16.2 0.0 0.039 14.6 0.0 1.8 1 1 1 2 2 2 0 Aspartyl protease DUF2532 PF10811.8 EGC36524.1 - 0.019 15.0 0.2 0.034 14.2 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2532) gag-asp_proteas PF13975.6 EGC36524.1 - 0.074 13.6 0.0 0.3 11.7 0.0 2.0 2 0 0 2 2 2 0 gag-polyprotein putative aspartyl protease DUF1411 PF07199.11 EGC36524.1 - 0.078 12.6 0.1 0.13 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) DUF1659 PF07872.11 EGC36524.1 - 0.54 10.0 2.4 2.4 7.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1659) FNIP PF05725.12 EGC36525.1 - 9.1e-30 102.6 33.7 2.3e-11 43.7 0.4 4.8 1 1 5 7 7 7 6 FNIP Repeat DUF538 PF04398.12 EGC36525.1 - 0.025 15.0 1.6 33 5.0 0.0 3.2 2 1 1 3 3 3 0 Protein of unknown function, DUF538 DUF3430 PF11912.8 EGC36527.1 - 4.8e-40 137.9 38.3 6.4e-40 137.5 38.1 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) COesterase PF00135.28 EGC36528.1 - 8.1e-118 394.5 0.0 3.1e-117 392.6 0.0 1.7 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC36528.1 - 0.0002 21.3 0.1 0.00082 19.3 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC36528.1 - 0.0025 17.3 0.3 0.004 16.6 0.3 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Endotoxin_N PF03945.14 EGC36529.1 - 1.4e-06 28.2 1.5 1.4e-06 28.2 1.5 2.6 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain COesterase PF00135.28 EGC36530.1 - 1.2e-116 390.6 0.0 3.1e-116 389.3 0.0 1.5 1 1 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC36530.1 - 1.9e-05 24.6 0.0 5.4e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC36530.1 - 0.0031 17.0 0.0 0.0048 16.4 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family KR PF08659.10 EGC36531.1 - 1.2e-11 44.9 0.0 1.5e-11 44.6 0.0 1.1 1 0 0 1 1 1 1 KR domain YcxB PF14317.6 EGC36531.1 - 0.067 12.9 0.6 0.067 12.9 0.6 1.9 2 0 0 2 2 2 0 YcxB-like protein PRANC PF09372.10 EGC36531.1 - 0.64 10.4 9.1 1 9.7 0.3 2.8 1 1 1 2 2 2 0 PRANC domain Methyltransf_31 PF13847.6 EGC36532.1 - 0.013 15.3 1.2 0.027 14.2 1.2 1.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGC36532.1 - 0.064 14.0 0.0 0.19 12.4 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36532.1 - 0.08 13.6 0.0 0.18 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain ColG_sub PF18496.1 EGC36532.1 - 0.33 11.1 4.8 0.15 12.3 1.8 2.0 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain DUF4264 PF14084.6 EGC36533.1 - 0.06 13.0 0.0 0.076 12.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) RNase_T PF00929.24 EGC36534.1 - 0.0004 21.0 1.3 0.0014 19.2 0.2 2.4 2 1 0 2 2 2 1 Exonuclease DUF5051 PF16473.5 EGC36534.1 - 0.00073 19.6 0.1 0.0032 17.5 0.1 2.2 1 1 0 1 1 1 1 3' exoribonuclease, RNase T-like FOXP-CC PF16159.5 EGC36534.1 - 0.011 16.3 0.1 0.032 14.9 0.1 1.8 1 0 0 1 1 1 0 FOXP coiled-coil domain Presenilin PF01080.17 EGC36537.1 - 7.8 5.1 7.1 9 4.9 7.1 1.0 1 0 0 1 1 1 0 Presenilin GATA PF00320.27 EGC36539.1 - 3.3e-08 33.0 2.4 3.3e-08 33.0 2.4 2.0 2 0 0 2 2 2 1 GATA zinc finger Zn-ribbon_8 PF09723.10 EGC36539.1 - 0.22 11.6 2.3 0.29 11.3 0.1 2.0 2 0 0 2 2 2 0 Zinc ribbon domain Rubredoxin_2 PF18073.1 EGC36539.1 - 5.3 6.9 6.0 9.2 6.1 0.0 2.9 3 0 0 3 3 3 0 Rubredoxin metal binding domain Homeodomain PF00046.29 EGC36542.1 - 1.5e-12 47.1 0.7 1.3e-06 28.2 0.0 2.6 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC36542.1 - 0.00032 20.5 0.1 0.023 14.6 0.0 2.8 1 1 0 2 2 2 1 Homeobox KN domain Ycf34 PF10718.9 EGC36543.1 - 0.076 13.7 1.1 0.17 12.6 0.1 2.0 2 0 0 2 2 2 0 Hypothetical chloroplast protein Ycf34 GATA PF00320.27 EGC36544.1 - 2.8e-07 30.0 8.9 1.4e-06 27.8 8.9 2.0 1 1 0 1 1 1 1 GATA zinc finger DUF4508 PF14969.6 EGC36544.1 - 0.042 14.1 0.2 0.057 13.7 0.2 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) AT_hook PF02178.19 EGC36544.1 - 0.055 13.4 7.4 0.11 12.4 7.4 1.6 1 0 0 1 1 1 0 AT hook motif RFX5_DNA_bdg PF14621.6 EGC36544.1 - 0.071 12.9 0.4 0.099 12.4 0.4 1.2 1 0 0 1 1 1 0 RFX5 DNA-binding domain F-box PF00646.33 EGC36546.1 - 0.00039 20.2 0.1 0.0007 19.4 0.1 1.5 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.7 EGC36546.1 - 0.021 14.7 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 F-box-like F-box_5 PF18511.1 EGC36546.1 - 0.19 11.3 0.2 0.37 10.4 0.2 1.6 1 0 0 1 1 1 0 F-box SIN1_PH PF16979.5 EGC36547.1 - 0.011 16.0 1.4 0.03 14.6 1.1 1.9 1 1 0 1 1 1 0 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology DDE_Tnp_1_7 PF13843.6 EGC36548.1 - 7.5e-14 51.8 1.2 1e-13 51.4 1.2 1.1 1 0 0 1 1 1 1 Transposase IS4 PPV_E2_N PF00508.17 EGC36549.1 - 0.023 14.0 0.4 0.038 13.3 0.4 1.3 1 1 0 1 1 1 0 E2 (early) protein, N terminal GATA PF00320.27 EGC36550.1 - 8.2e-08 31.7 3.8 2.2e-07 30.3 3.8 1.7 1 1 0 1 1 1 1 GATA zinc finger Gln-synt_N PF03951.19 EGC36551.1 - 0.15 11.8 0.0 0.26 11.0 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Ribophorin_II PF05817.14 EGC36552.1 - 1.8e-105 353.9 19.8 2.2e-105 353.6 19.8 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II CIF PF16374.5 EGC36552.1 - 0.056 13.5 0.7 0.64 10.1 0.0 2.4 2 0 0 2 2 2 0 Cycle inhibiting factor (CIF) Pkinase_Tyr PF07714.17 EGC36553.1 - 9.6e-44 149.6 0.0 1.5e-43 148.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC36553.1 - 3.5e-43 147.9 0.3 9.2e-43 146.5 0.3 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC36553.1 - 0.0086 14.9 0.0 0.014 14.2 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase RNase_T PF00929.24 EGC36555.1 - 0.0016 19.0 0.0 0.053 14.1 0.0 2.6 1 1 1 2 2 2 1 Exonuclease DUF5497 PF17601.2 EGC36555.1 - 0.088 13.1 0.8 0.53 10.6 0.1 2.5 2 1 1 3 3 3 0 Family of unknown function (DUF5497) DUF5051 PF16473.5 EGC36555.1 - 0.13 12.3 0.0 0.32 10.9 0.0 1.7 2 0 0 2 2 2 0 3' exoribonuclease, RNase T-like FNIP PF05725.12 EGC36556.1 - 6.4e-31 106.3 34.9 3.5e-10 39.9 2.3 9.6 5 3 5 10 10 10 9 FNIP Repeat DUF1870 PF08965.10 EGC36557.1 - 0.06 13.4 0.5 0.11 12.5 0.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1870) FNIP PF05725.12 EGC36560.1 - 1.5e-40 137.1 44.6 5.1e-12 45.8 0.8 9.4 6 2 5 11 11 11 8 FNIP Repeat DNA_methylase PF00145.17 EGC36561.1 - 0.00025 20.5 0.0 0.00029 20.3 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Pkinase PF00069.25 EGC36562.1 - 1.3e-18 67.4 0.0 1.1e-16 61.0 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36562.1 - 2e-17 63.3 0.0 2.7e-08 33.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase APH PF01636.23 EGC36562.1 - 0.00049 20.1 0.0 0.00063 19.7 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.14 EGC36562.1 - 0.0018 17.6 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Fructosamine kinase zf-C2H2 PF00096.26 EGC36563.1 - 0.0026 18.1 0.3 0.0067 16.8 0.3 1.8 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-H2C2_5 PF13909.6 EGC36563.1 - 0.13 12.0 0.3 0.13 12.0 0.3 1.8 2 0 0 2 2 2 0 C2H2-type zinc-finger domain Lipase_GDSL PF00657.22 EGC36564.1 - 0.049 13.6 0.0 0.056 13.4 0.0 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase DUF3439 PF11921.8 EGC36565.1 - 0.029 14.4 8.7 0.038 14.0 8.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.12 EGC36565.1 - 0.03 12.3 7.5 0.03 12.3 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Mucin PF01456.17 EGC36565.1 - 0.27 11.2 16.2 0.34 10.9 16.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.11 EGC36565.1 - 3.8 5.6 15.0 4.2 5.4 15.0 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC36566.1 - 0.0036 17.3 6.2 0.0056 16.7 6.2 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein APG6_N PF17675.1 EGC36566.1 - 0.0077 16.8 2.0 0.0077 16.8 2.0 3.1 2 1 1 3 3 3 1 Apg6 coiled-coil region FF PF01846.19 EGC36566.1 - 0.016 15.4 1.8 0.87 9.8 0.2 2.9 2 0 0 2 2 2 0 FF domain DUF3439 PF11921.8 EGC36566.1 - 0.02 14.8 6.2 0.044 13.7 6.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.11 EGC36566.1 - 0.06 11.5 7.4 0.083 11.1 7.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DRE2_N PF16803.5 EGC36567.1 - 0.061 13.6 0.1 0.092 13.0 0.1 1.2 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus Tmpp129 PF10272.9 EGC36570.1 - 0.00062 19.2 17.3 0.043 13.1 10.8 2.4 2 0 0 2 2 2 2 Putative transmembrane protein precursor DUF3439 PF11921.8 EGC36570.1 - 0.52 10.3 15.9 1.7 8.6 1.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SBP_bac_6 PF13343.6 EGC36571.1 - 0.042 13.3 0.0 0.062 12.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial extracellular solute-binding protein Acetyltransf_10 PF13673.7 EGC36571.1 - 0.061 13.3 0.2 0.44 10.5 0.1 2.1 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC36571.1 - 0.12 12.5 0.0 0.33 11.1 0.0 1.7 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase IP_trans PF02121.18 EGC36572.1 - 9.2e-113 375.9 0.1 1.2e-112 375.5 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein PcfK PF14058.6 EGC36572.1 - 0.043 14.1 0.5 0.072 13.4 0.5 1.3 1 0 0 1 1 1 0 PcfK-like protein eRF1_1 PF03463.15 EGC36573.1 - 1.3e-45 154.5 0.7 2.5e-45 153.6 0.7 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.15 EGC36573.1 - 1.9e-26 92.9 0.1 3.4e-26 92.1 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.15 EGC36573.1 - 2.9e-26 92.2 0.1 6.9e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 DUF5601 PF18151.1 EGC36573.1 - 0.33 11.3 3.1 4.1 7.8 0.6 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) Acetyltransf_1 PF00583.25 EGC36574.1 - 5.9e-20 71.7 0.0 9e-09 35.6 0.0 2.1 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC36574.1 - 1.5e-15 57.2 0.0 2.5e-08 33.9 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC36574.1 - 5.5e-11 42.7 0.0 2e-06 28.1 0.0 2.4 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC36574.1 - 3.1e-06 27.9 0.0 0.01 16.5 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC36574.1 - 0.0012 18.9 0.0 0.074 13.2 0.0 2.5 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase Acetyltransf_8 PF13523.6 EGC36574.1 - 0.0014 18.3 0.2 0.018 14.7 0.0 2.1 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC36574.1 - 0.0024 18.0 0.0 1.4 9.0 0.1 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC36574.1 - 0.0063 16.5 0.0 0.15 12.0 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_15 PF17013.5 EGC36574.1 - 0.77 9.2 5.9 1 8.8 3.0 2.3 2 1 0 2 2 2 0 Putative acetyl-transferase Sec7 PF01369.20 EGC36575.1 - 3.3e-57 193.1 14.1 7.4e-57 192.0 7.3 3.3 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.7 EGC36575.1 - 5.6e-35 120.6 3.4 5.6e-35 120.6 3.4 3.9 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGC36575.1 - 1.7e-29 101.5 1.7 1.7e-29 101.5 1.7 4.6 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) DCB PF16213.5 EGC36575.1 - 2.4e-23 82.7 5.4 2.4e-23 82.7 5.4 5.1 4 1 0 4 4 4 2 Dimerisation and cyclophilin-binding domain of Mon2 ACCA PF03255.14 EGC36575.1 - 0.16 11.9 7.4 0.84 9.5 7.4 2.3 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RPN7 PF10602.9 EGC36575.1 - 0.43 10.3 11.7 2.2 7.9 0.0 3.5 3 1 1 4 4 4 0 26S proteasome subunit RPN7 DUF2203 PF09969.9 EGC36575.1 - 0.6 10.8 6.3 2.5 8.8 6.3 2.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.12 EGC36575.1 - 2.3 8.3 11.6 8.7 6.4 11.6 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4407 PF14362.6 EGC36575.1 - 3.2 7.0 13.1 6.7 6.0 13.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PH PF00169.29 EGC36576.1 - 2.9e-07 31.0 4.8 1.1e-06 29.1 1.9 3.3 2 1 0 2 2 2 1 PH domain PH_2 PF08458.10 EGC36576.1 - 0.026 14.9 0.6 2.1 8.7 0.0 2.9 2 0 0 2 2 2 0 Plant pleckstrin homology-like region ApoO PF09769.9 EGC36576.1 - 1.5 8.8 5.8 0.63 10.0 0.2 3.0 3 0 0 3 3 3 0 Apolipoprotein O SlyX PF04102.12 EGC36576.1 - 9.5 6.9 23.0 0.19 12.3 1.6 4.0 2 1 0 3 3 3 0 SlyX Helicase_C PF00271.31 EGC36577.1 - 9.1e-19 67.8 1.0 4e-17 62.6 0.2 3.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36577.1 - 9.6e-15 55.0 0.0 9.6e-15 55.0 0.0 3.0 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC36577.1 - 2.6e-12 46.9 0.2 4.3e-11 42.9 0.1 2.6 2 1 1 3 3 3 1 DEAD/DEAH box helicase dsrm PF00035.26 EGC36577.1 - 2e-08 34.8 1.0 0.00011 22.8 0.0 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif Phi-29_GP4 PF05464.11 EGC36578.1 - 0.029 14.6 0.6 0.097 13.0 0.1 2.1 1 1 0 2 2 2 0 Phi-29-like late genes activator (early protein GP4) RMP PF14996.6 EGC36578.1 - 0.28 11.4 5.6 3.9 7.7 0.1 2.6 1 1 2 3 3 3 0 Retinal Maintenance ATG16 PF08614.11 EGC36578.1 - 0.89 9.7 20.2 0.51 10.5 17.5 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) ParB PF08775.10 EGC36580.1 - 0.015 15.8 1.7 0.033 14.7 0.1 2.1 2 1 0 2 2 2 0 ParB family DUF3502 PF12010.8 EGC36580.1 - 0.13 12.9 1.5 0.18 12.5 0.3 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3502) PRESAN PF09687.10 EGC36582.1 - 0.26 11.8 8.3 0.48 11.0 8.2 1.5 1 1 0 1 1 1 0 Plasmodium RESA N-terminal PLAC8 PF04749.17 EGC36584.1 - 5.8e-17 62.5 14.7 6.8e-17 62.3 14.7 1.1 1 0 0 1 1 1 1 PLAC8 family Sel1 PF08238.12 EGC36588.1 - 3.7e-15 56.0 11.4 4.9e-06 27.0 1.5 5.1 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.6 EGC36588.1 - 0.004 17.7 0.1 0.17 12.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF2706 PF10913.8 EGC36588.1 - 0.23 11.3 0.9 0.59 10.0 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) TPR_14 PF13428.6 EGC36589.1 - 1.9e-13 50.0 7.8 0.015 16.1 0.1 8.9 6 3 4 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGC36589.1 - 1.7e-07 31.7 0.8 0.17 12.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC36589.1 - 2.8e-07 30.2 5.3 0.14 12.4 0.0 6.1 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC36589.1 - 1.6e-06 28.5 14.0 0.52 10.9 0.0 6.8 5 2 3 8 8 8 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC36589.1 - 6.3e-05 23.1 2.2 0.041 14.3 0.0 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC36589.1 - 0.00012 21.9 16.7 0.93 9.8 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat Suf PF05843.14 EGC36589.1 - 0.0011 19.1 0.3 0.0011 19.1 0.3 6.1 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) Macoilin PF09726.9 EGC36589.1 - 0.0059 15.2 32.6 0.0082 14.8 32.6 1.2 1 0 0 1 1 1 1 Macoilin family TPR_1 PF00515.28 EGC36589.1 - 0.12 12.2 7.2 5.5 7.0 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat CUE PF02845.16 EGC36590.1 - 6.3e-11 41.8 0.0 2e-10 40.2 0.0 1.9 1 0 0 1 1 1 1 CUE domain F5_F8_type_C PF00754.25 EGC36591.1 - 4.5e-05 23.6 0.1 5.6e-05 23.3 0.1 1.2 1 0 0 1 1 1 1 F5/8 type C domain ANAPC10 PF03256.16 EGC36591.1 - 0.043 13.5 0.0 0.16 11.6 0.0 1.7 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 10 (APC10) ABC2_membrane PF01061.24 EGC36592.1 - 8.6e-39 133.1 17.6 1.6e-38 132.3 17.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC36592.1 - 3.3e-25 89.2 0.0 2.2e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter RsgA_GTPase PF03193.16 EGC36592.1 - 0.0032 17.4 1.3 0.0095 15.8 0.2 2.1 2 0 0 2 2 2 1 RsgA GTPase AAA_21 PF13304.6 EGC36592.1 - 0.0058 16.5 5.5 0.16 11.8 0.2 2.4 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGC36592.1 - 0.0071 16.6 0.5 0.21 11.9 0.5 2.8 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC36592.1 - 0.01 16.2 0.1 0.019 15.4 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGC36592.1 - 0.019 15.3 0.1 0.055 13.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGC36592.1 - 0.024 14.9 0.6 0.038 14.2 0.6 1.2 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGC36592.1 - 0.027 14.4 0.3 0.32 10.9 0.1 2.2 2 0 0 2 2 2 0 NTPase AAA_29 PF13555.6 EGC36592.1 - 0.031 14.0 0.3 0.069 12.9 0.3 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.12 EGC36592.1 - 0.036 14.0 0.0 0.069 13.1 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.23 EGC36592.1 - 0.039 14.1 0.6 0.091 12.9 0.2 1.8 2 0 0 2 2 2 0 50S ribosome-binding GTPase T2SSE PF00437.20 EGC36592.1 - 0.059 12.4 0.2 0.1 11.7 0.2 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SMC_N PF02463.19 EGC36592.1 - 0.11 11.9 0.3 6.6 6.1 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.6 EGC36592.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC36592.1 - 0.25 11.1 0.3 2.3 7.9 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_23 PF13476.6 EGC36592.1 - 0.26 11.8 3.1 1.2 9.6 1.0 2.2 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.7 EGC36592.1 - 0.71 8.9 26.8 1.9 7.5 26.8 1.8 1 1 0 1 1 1 0 ABC-2 family transporter protein Img2 PF05046.14 EGC36593.1 - 9.3e-19 67.5 0.2 2.1e-18 66.4 0.0 1.6 2 1 0 2 2 2 1 Mitochondrial large subunit ribosomal protein (Img2) DUF5563 PF17718.1 EGC36593.1 - 0.0096 15.5 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5563) L51_S25_CI-B8 PF05047.16 EGC36593.1 - 0.047 13.6 0.1 0.12 12.3 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain RMP PF14996.6 EGC36594.1 - 0.054 13.7 5.6 3.9 7.7 0.1 2.8 1 1 1 2 2 2 0 Retinal Maintenance Phi-29_GP4 PF05464.11 EGC36594.1 - 0.12 12.7 2.2 0.18 12.1 0.1 2.4 2 1 1 3 3 3 0 Phi-29-like late genes activator (early protein GP4) APG6_N PF17675.1 EGC36594.1 - 4 8.0 13.4 5.6 7.5 10.4 2.6 2 0 0 2 2 2 0 Apg6 coiled-coil region AFP PF02420.15 EGC36596.1 - 0.017 15.4 0.4 0.081 13.3 0.4 2.2 1 0 0 1 1 1 0 Insect antifreeze protein repeat Ocnus PF05005.15 EGC36597.1 - 1.7e-11 44.2 0.0 2.8e-11 43.5 0.0 1.4 1 1 0 1 1 1 1 Janus/Ocnus family (Ocnus) Transket_pyr PF02779.24 EGC36599.1 - 1.7e-57 194.0 0.0 3.2e-57 193.1 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain OxoGdeHyase_C PF16870.5 EGC36599.1 - 1.7e-53 180.4 0.0 3e-53 179.6 0.0 1.4 1 0 0 1 1 1 1 2-oxoglutarate dehydrogenase C-terminal E1_dh PF00676.20 EGC36599.1 - 2.8e-46 157.9 0.0 4.7e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3574 PF12098.8 EGC36599.1 - 0.014 15.1 0.7 0.099 12.4 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3574) G-alpha PF00503.20 EGC36600.1 - 1.7e-87 293.8 16.4 2e-87 293.6 16.4 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC36600.1 - 2e-12 46.9 0.1 1.4e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC36600.1 - 4.3e-05 23.7 0.1 0.35 11.1 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGC36600.1 - 8.2e-05 22.1 6.6 0.00057 19.3 0.7 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.22 EGC36600.1 - 0.00015 21.5 1.1 0.15 11.6 0.1 2.5 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.23 EGC36600.1 - 0.0031 17.6 0.1 1.2 9.3 0.0 2.7 3 0 0 3 3 3 2 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC36600.1 - 0.087 12.3 0.6 0.56 9.7 0.1 2.4 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PPR_2 PF13041.6 EGC36601.1 - 6.1e-08 32.7 8.1 0.14 12.4 0.2 6.4 6 0 0 6 6 6 3 PPR repeat family PPR PF01535.20 EGC36601.1 - 0.00079 19.5 3.8 2.9 8.3 0.0 4.7 5 0 0 5 5 5 2 PPR repeat TPR_19 PF14559.6 EGC36601.1 - 0.00079 19.9 0.7 1.3 9.6 0.0 3.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC36601.1 - 0.09 12.9 1.6 22 5.5 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_Cef PF11831.8 EGC36602.1 - 2.1e-35 122.5 23.3 2.1e-35 122.5 23.3 2.9 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.31 EGC36602.1 - 2e-21 75.9 4.9 1.7e-10 40.9 0.6 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC36602.1 - 3.6e-18 65.5 9.1 2.6e-12 46.8 3.0 3.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGC36602.1 - 0.15 12.3 1.5 0.37 11.0 0.1 2.4 2 0 0 2 2 2 0 SANT/Myb-like domain of DAMP1 GYF PF02213.16 EGC36603.1 - 1.5e-17 62.9 0.2 1.5e-17 62.9 0.2 2.6 2 0 0 2 2 2 1 GYF domain GYF_2 PF14237.6 EGC36603.1 - 0.12 12.2 0.0 0.12 12.2 0.0 3.0 4 0 0 4 4 4 0 GYF domain 2 Peptidase_C48 PF02902.19 EGC36604.1 - 4.1e-15 56.2 0.5 1.7e-14 54.2 0.5 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain zf-C3HC4_2 PF13923.6 EGC36605.1 - 3.6e-10 39.5 10.0 3.6e-10 39.5 10.0 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) SAP PF02037.27 EGC36605.1 - 4.6e-09 35.8 0.1 9.3e-09 34.8 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.25 EGC36605.1 - 4.3e-07 29.7 11.7 4.3e-07 29.7 11.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36605.1 - 8.9e-07 29.1 12.7 1.6e-06 28.3 9.7 2.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC36605.1 - 1e-06 28.6 9.4 1.8e-05 24.6 10.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC36605.1 - 9.5e-06 25.4 10.2 9.5e-06 25.4 10.2 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_10 PF16685.5 EGC36605.1 - 2.8e-05 24.2 10.1 2.8e-05 24.2 10.1 2.3 1 1 1 2 2 2 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC36605.1 - 0.00018 21.6 19.7 0.00033 20.8 11.9 2.9 3 0 0 3 3 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC36605.1 - 0.00036 20.4 9.7 0.00036 20.4 9.7 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.6 EGC36605.1 - 0.0022 17.8 5.0 0.0038 17.1 5.0 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein FAM76 PF16046.5 EGC36605.1 - 0.0057 16.0 11.7 0.0057 16.0 11.7 3.1 1 1 3 4 4 1 1 FAM76 protein zf-rbx1 PF12678.7 EGC36605.1 - 0.0092 16.2 12.0 0.016 15.5 7.8 3.1 2 1 0 2 2 2 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC36605.1 - 1.5 8.8 14.2 44 4.0 11.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 START PF01852.19 EGC36606.1 - 1.8e-07 30.8 0.0 5.7e-07 29.2 0.0 1.7 1 1 0 1 1 1 1 START domain Uso1_p115_C PF04871.13 EGC36606.1 - 0.38 11.1 4.3 0.91 9.9 4.3 1.6 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Pkinase PF00069.25 EGC36607.1 - 4.5e-65 219.6 0.1 6.7e-43 146.9 0.1 2.9 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36607.1 - 1.4e-31 109.7 0.1 4.9e-22 78.4 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC36607.1 - 0.00093 18.6 0.0 0.095 12.0 0.0 2.9 2 1 1 3 3 3 1 Kinase-like APH PF01636.23 EGC36607.1 - 0.0022 18.0 0.1 0.17 11.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.14 EGC36607.1 - 0.027 13.8 0.0 0.047 13.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TAFII28 PF04719.14 EGC36608.1 - 6.9e-36 122.2 0.5 7.8e-36 122.0 0.5 1.0 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.23 EGC36608.1 - 0.014 15.6 0.1 0.02 15.2 0.1 1.4 1 1 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone MafB19-deam PF14437.6 EGC36609.1 - 9e-12 44.9 3.8 1.9e-09 37.4 0.0 3.1 3 1 1 4 4 4 2 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EGC36609.1 - 1.6e-10 40.8 0.4 1.2e-09 37.9 0.4 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EGC36609.1 - 0.0063 16.6 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase RLAN PF14401.6 EGC36609.1 - 0.035 13.8 5.2 0.98 9.1 1.1 3.1 3 0 0 3 3 3 0 RimK-like ATPgrasp N-terminal domain Phage_Gp23 PF10669.9 EGC36609.1 - 0.94 9.8 0.0 0.94 9.8 0.0 3.6 4 1 0 4 4 4 0 Protein gp23 (Bacteriophage A118) DnaJ_C PF01556.18 EGC36610.1 - 6.2e-41 139.9 0.1 8.8e-41 139.4 0.1 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGC36610.1 - 1.4e-24 86.0 2.1 3e-24 84.9 2.1 1.6 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGC36610.1 - 1.8e-12 47.4 22.2 4e-12 46.3 22.2 1.6 1 0 0 1 1 1 1 DnaJ central domain KAsynt_C_assoc PF16197.5 EGC36610.1 - 0.14 12.6 0.1 0.29 11.6 0.1 1.5 1 0 0 1 1 1 0 Ketoacyl-synthetase C-terminal extension Anti-TRAP PF15777.5 EGC36610.1 - 0.35 10.9 23.2 0.18 11.8 4.7 3.4 2 1 1 3 3 3 0 Tryptophan RNA-binding attenuator protein inhibitory protein HscB_4_cys PF18256.1 EGC36610.1 - 0.48 10.3 2.3 1.7 8.5 2.3 2.0 1 0 0 1 1 1 0 Co-chaperone HscB tetracysteine metal binding motif zf-RING_10 PF16685.5 EGC36610.1 - 1.6 8.9 6.9 0.086 13.0 1.1 1.8 2 0 0 2 2 2 0 zinc RING finger of MSL2 TPR_2 PF07719.17 EGC36611.1 - 2e-08 33.7 6.3 0.058 13.5 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC36611.1 - 5.7e-08 32.4 6.9 0.12 12.7 0.0 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.6 EGC36611.1 - 8.1e-08 32.7 0.0 0.23 12.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC36611.1 - 9.1e-08 32.6 0.0 0.32 11.7 0.0 3.7 3 1 1 4 4 4 4 Tetratricopeptide repeat TPR_1 PF00515.28 EGC36611.1 - 9.1e-06 25.3 5.6 0.038 13.8 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC36611.1 - 1.8e-05 24.9 0.1 0.057 13.7 0.1 3.6 3 2 1 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC36611.1 - 2.2e-05 24.9 0.2 38 5.5 0.0 4.9 4 1 1 5 5 5 0 Tetratricopeptide repeat TOM20_plant PF06552.12 EGC36611.1 - 0.0022 17.8 7.3 0.0062 16.3 1.7 2.8 1 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 LPD3 PF18798.1 EGC36611.1 - 0.0025 18.0 1.7 0.011 15.9 0.0 2.6 2 2 0 2 2 2 1 Large polyvalent protein-associated domain 3 TPR_11 PF13414.6 EGC36611.1 - 0.0047 16.6 4.6 12 5.7 0.0 4.6 5 0 0 5 5 5 1 TPR repeat TPR_17 PF13431.6 EGC36611.1 - 0.013 15.9 0.4 8 7.1 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF627 PF04781.12 EGC36611.1 - 0.014 15.4 0.6 0.1 12.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF627) REJ PF02010.15 EGC36612.1 - 1.5e-46 159.2 19.7 9e-44 150.0 8.9 2.9 2 1 1 3 3 3 2 REJ domain Glycos_transf_2 PF00535.26 EGC36612.1 - 5.5e-23 81.6 0.1 1.2e-22 80.5 0.1 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glycos_transf_1 PF00534.20 EGC36612.1 - 3.9e-13 49.3 0.0 4.7e-12 45.8 0.0 2.9 3 0 0 3 3 3 1 Glycosyl transferases group 1 Glyco_tranf_2_2 PF10111.9 EGC36612.1 - 1.1e-12 48.0 2.6 1.4e-11 44.4 2.5 2.2 1 1 0 1 1 1 1 Glycosyltransferase like family 2 TIG PF01833.24 EGC36612.1 - 1e-10 41.5 2.5 1e-10 41.5 2.5 4.1 3 0 0 3 3 3 1 IPT/TIG domain GPS PF01825.21 EGC36612.1 - 2.2e-09 37.7 7.2 2.2e-09 37.7 7.2 1.9 2 0 0 2 2 1 1 GPCR proteolysis site, GPS, motif Glyco_transf_4 PF13439.6 EGC36612.1 - 2.3e-08 34.2 0.0 4e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.6 EGC36612.1 - 4e-08 33.8 0.0 2.2e-07 31.4 0.0 2.1 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.6 EGC36612.1 - 6.6e-08 32.7 0.0 1.4e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_4_4 PF13579.6 EGC36612.1 - 5.2e-06 27.0 0.0 7.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Protocadherin PF08374.11 EGC36612.1 - 0.00038 20.5 5.0 0.0009 19.3 5.0 1.6 1 0 0 1 1 1 1 Protocadherin Insulin_TMD PF17870.1 EGC36612.1 - 0.00044 20.3 1.2 0.0012 18.8 1.2 1.7 1 0 0 1 1 1 1 Insulin receptor trans-membrane segment Glyco_transf_7C PF02709.14 EGC36612.1 - 0.00049 19.7 0.0 0.0011 18.5 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_transf_5 PF08323.11 EGC36612.1 - 0.0057 16.4 0.0 0.033 13.9 0.0 2.4 2 1 0 2 2 2 1 Starch synthase catalytic domain DUF4834 PF16118.5 EGC36612.1 - 0.013 16.5 3.0 0.059 14.3 3.0 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Glyco_tranf_2_4 PF13704.6 EGC36612.1 - 0.013 15.9 0.1 0.032 14.7 0.1 1.7 1 0 0 1 1 1 0 Glycosyl transferase family 2 Peptidase_S49_N PF08496.10 EGC36612.1 - 0.062 13.4 10.9 0.2 11.7 10.9 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal EphA2_TM PF14575.6 EGC36612.1 - 0.066 14.1 0.0 0.17 12.8 0.0 1.8 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AIF_C PF14721.6 EGC36612.1 - 0.18 12.1 5.9 0.51 10.7 5.9 1.8 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Connexin PF00029.19 EGC36612.1 - 0.19 11.5 5.4 0.36 10.6 5.4 1.3 1 0 0 1 1 1 0 Connexin Zip PF02535.22 EGC36612.1 - 0.23 10.6 4.3 0.38 9.9 4.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter RNA_pol_Rpc4 PF05132.14 EGC36612.1 - 0.68 10.4 10.2 0.37 11.2 7.5 2.0 2 0 0 2 2 1 0 RNA polymerase III RPC4 DUF2681 PF10883.8 EGC36612.1 - 1 9.8 9.2 2.3 8.7 8.0 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF2681) MAP17 PF15807.5 EGC36612.1 - 2.5 8.3 10.0 5.9 7.2 10.0 1.6 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Ureide_permease PF07168.11 EGC36612.1 - 3.3 6.4 7.7 0.54 9.0 3.2 1.9 2 0 0 2 2 2 0 Ureide permease Presenilin PF01080.17 EGC36612.1 - 4.2 6.0 12.6 7.2 5.3 12.6 1.3 1 0 0 1 1 1 0 Presenilin BACON PF13004.7 EGC36612.1 - 8.1 6.5 10.2 9.2 6.4 0.0 3.4 3 0 0 3 3 2 0 Putative binding domain, N-terminal ATP_bind_1 PF03029.17 EGC36613.1 - 4.2e-79 265.7 0.0 6.3e-79 265.2 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein CbiA PF01656.23 EGC36613.1 - 6.7e-05 22.9 0.0 0.0001 22.4 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGC36613.1 - 9.8e-05 22.3 0.2 0.069 13.1 0.0 2.7 2 1 1 3 3 3 2 AAA domain CLP1_P PF16575.5 EGC36613.1 - 0.0026 17.6 0.0 0.0052 16.6 0.0 1.5 1 0 0 1 1 1 1 mRNA cleavage and polyadenylation factor CLP1 P-loop MeaB PF03308.16 EGC36613.1 - 0.0048 15.9 0.0 0.0078 15.2 0.0 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB DRIM PF07539.12 EGC36613.1 - 0.011 14.1 0.0 0.015 13.6 0.0 1.1 1 0 0 1 1 1 0 Down-regulated in metastasis AAA_10 PF12846.7 EGC36613.1 - 0.019 13.9 0.0 0.039 12.9 0.0 1.5 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.6 EGC36613.1 - 0.035 13.8 0.0 0.058 13.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.10 EGC36613.1 - 0.05 13.1 0.0 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 RNA_helicase PF00910.22 EGC36613.1 - 0.066 13.6 0.0 0.26 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA_22 PF13401.6 EGC36613.1 - 0.076 13.3 0.0 0.19 12.0 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC36613.1 - 0.091 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGC36613.1 - 0.12 12.8 0.0 0.22 12.0 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.22 EGC36613.1 - 0.12 12.0 0.0 0.23 11.1 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain GCV_H PF01597.19 EGC36614.1 - 0.024 14.5 0.4 0.59 10.0 0.4 2.6 1 1 0 1 1 1 0 Glycine cleavage H-protein UQ_con PF00179.26 EGC36615.1 - 2.6e-49 166.5 0.0 2.9e-49 166.3 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.6 EGC36615.1 - 0.00024 20.8 0.0 0.00026 20.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.22 EGC36615.1 - 0.014 15.7 0.2 0.02 15.2 0.2 1.3 1 1 0 1 1 1 0 RWD domain UEV PF05743.13 EGC36615.1 - 0.071 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 UEV domain CDP-OH_P_transf PF01066.21 EGC36616.1 - 4.2e-16 59.5 0.1 4.2e-16 59.5 0.1 3.4 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HR_lesion PF05514.11 EGC36616.1 - 0.09 13.0 1.8 15 5.7 0.9 2.5 2 0 0 2 2 2 0 HR-like lesion-inducing DUF3128 PF11326.8 EGC36617.1 - 4.6e-12 46.1 2.1 8.6e-12 45.3 2.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) PigN PF04987.14 EGC36618.1 - 2.5e-122 409.0 51.3 3.9e-122 408.4 51.3 1.3 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.22 EGC36618.1 - 6.1e-15 55.7 0.2 3.2e-11 43.4 0.2 2.2 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.23 EGC36618.1 - 2.2e-05 24.0 0.0 4.6e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Sulfatase IPK PF03770.16 EGC36619.1 - 3.5e-35 121.6 4.3 3.5e-35 121.6 4.3 3.0 2 1 0 2 2 2 1 Inositol polyphosphate kinase 3Beta_HSD PF01073.19 EGC36620.1 - 7.4e-30 103.9 0.2 1e-29 103.5 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC36620.1 - 1.1e-27 97.0 0.0 1.4e-27 96.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGC36620.1 - 9.9e-24 83.9 0.0 2.2e-23 82.7 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGC36620.1 - 2.2e-19 70.1 0.0 4e-19 69.2 0.0 1.4 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC36620.1 - 3.1e-16 59.8 0.0 4.3e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGC36620.1 - 3.4e-11 42.8 0.0 5.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC36620.1 - 6e-11 42.0 0.0 1e-10 41.2 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.13 EGC36620.1 - 1.8e-06 27.7 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family KR PF08659.10 EGC36620.1 - 2.1e-05 24.5 0.0 0.00053 19.9 0.0 2.2 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGC36620.1 - 0.0068 15.9 0.1 0.13 11.7 0.0 2.6 2 1 0 2 2 2 1 short chain dehydrogenase NAD_binding_3 PF03447.16 EGC36620.1 - 0.067 13.9 0.0 13 6.5 0.0 2.5 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.24 EGC36620.1 - 0.12 12.8 0.0 0.29 11.6 0.0 1.7 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Dicty_CTDC PF00526.18 EGC36621.1 - 5.6e-07 29.3 23.9 5.3e-06 26.2 4.8 6.0 6 0 0 6 6 6 2 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC36621.1 - 8.6e-07 28.9 0.0 1.6e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 PA14 domain PT PF04886.12 EGC36621.1 - 2.4 7.8 18.4 4.7 6.8 18.4 1.5 1 0 0 1 1 1 0 PT repeat Proteasome PF00227.26 EGC36622.1 - 1.1e-47 162.0 0.0 1.4e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC36622.1 - 8.4e-11 41.3 0.2 1.3e-10 40.7 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature ETF_QO PF05187.13 EGC36623.1 - 9.7e-46 154.2 0.1 1.6e-45 153.5 0.1 1.4 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S FAD_binding_2 PF00890.24 EGC36623.1 - 7.3e-09 35.2 0.3 1.3e-05 24.5 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.24 EGC36623.1 - 7.1e-07 29.1 0.8 0.0017 18.0 0.7 2.3 1 1 1 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC36623.1 - 3e-06 27.4 0.0 2.5e-05 24.4 0.0 2.3 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.17 EGC36623.1 - 8.5e-06 25.2 0.1 1.6e-05 24.3 0.1 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.14 EGC36623.1 - 9.1e-06 25.1 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGC36623.1 - 0.00011 21.4 0.3 0.00015 20.9 0.3 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein HI0933_like PF03486.14 EGC36623.1 - 0.00012 20.9 0.6 0.00025 19.9 0.7 1.4 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox_3 PF13738.6 EGC36623.1 - 0.00041 19.7 0.1 0.00064 19.1 0.1 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC36623.1 - 0.00048 20.6 0.0 0.22 12.1 0.0 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGC36623.1 - 0.00099 19.1 0.0 0.0016 18.5 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_binding_3 PF01494.19 EGC36623.1 - 0.0015 17.8 0.0 0.0024 17.2 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGC36623.1 - 0.0031 16.9 0.0 0.0043 16.4 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Trp_halogenase PF04820.14 EGC36623.1 - 0.014 14.3 0.0 1.1 8.1 0.2 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.6 EGC36623.1 - 0.036 13.2 0.0 0.053 12.6 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) Fer4_7 PF12838.7 EGC36623.1 - 0.079 13.6 0.4 0.18 12.4 0.4 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain GIDA PF01134.22 EGC36623.1 - 0.1 11.7 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A Tom7 PF08038.12 EGC36623.1 - 0.15 11.8 0.1 0.36 10.5 0.1 1.6 1 0 0 1 1 1 0 TOM7 family DUF3430 PF11912.8 EGC36624.1 - 2.3e-26 93.2 17.3 2.6e-26 93.0 17.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) COX15-CtaA PF02628.15 EGC36625.1 - 2.2e-113 378.6 2.0 2.2e-113 378.6 2.0 1.3 2 0 0 2 2 1 1 Cytochrome oxidase assembly protein DUF719 PF05334.13 EGC36625.1 - 0.0007 19.8 1.5 0.0012 19.1 1.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF719) DDHD PF02862.17 EGC36625.1 - 0.0084 16.3 0.2 0.011 16.0 0.2 1.2 1 0 0 1 1 1 1 DDHD domain MCU PF04678.13 EGC36625.1 - 0.026 14.6 0.1 0.068 13.3 0.1 1.7 1 0 0 1 1 1 0 Mitochondrial calcium uniporter AIF_C PF14721.6 EGC36625.1 - 0.047 14.0 2.3 0.088 13.2 2.3 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Cyt_bd_oxida_I PF01654.17 EGC36625.1 - 0.064 11.9 3.4 0.39 9.3 0.1 2.2 2 0 0 2 2 2 0 Cytochrome bd terminal oxidase subunit I DUF2370 PF10176.9 EGC36625.1 - 0.095 12.3 0.8 0.16 11.6 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Presenilin PF01080.17 EGC36625.1 - 0.17 10.7 1.9 0.26 10.0 1.9 1.2 1 0 0 1 1 1 0 Presenilin DUF4834 PF16118.5 EGC36625.1 - 0.19 12.7 6.7 0.41 11.6 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) RPA43_OB PF17875.1 EGC36625.1 - 0.2 12.3 3.2 0.36 11.4 3.2 1.3 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I DUF4820 PF16091.5 EGC36625.1 - 1.1 8.6 6.0 1.7 8.0 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) CopD PF05425.13 EGC36625.1 - 1.7 9.1 8.9 5.1 7.5 0.0 3.8 4 0 0 4 4 4 0 Copper resistance protein D Peptidase_S49_N PF08496.10 EGC36625.1 - 2 8.5 7.3 4.2 7.4 7.3 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal SNF2_N PF00176.23 EGC36626.1 - 1.8e-25 89.4 0.0 3e-25 88.7 0.0 1.2 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC36626.1 - 5.1e-11 42.9 0.0 1.8e-10 41.1 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36626.1 - 7.4e-06 26.1 0.0 0.00082 19.4 0.0 3.0 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC36626.1 - 0.0004 20.2 0.3 0.061 13.1 0.1 3.2 2 1 0 2 2 2 1 DEAD/DEAH box helicase ERCC3_RAD25_C PF16203.5 EGC36626.1 - 0.0013 18.0 0.0 0.0025 17.1 0.0 1.4 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase HARP PF07443.13 EGC36626.1 - 0.034 13.8 0.4 0.098 12.3 0.1 2.0 2 0 0 2 2 2 0 HepA-related protein (HARP) Flavi_DEAD PF07652.14 EGC36626.1 - 0.17 11.9 0.0 0.35 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DZR PF12773.7 EGC36627.1 - 6.8e-05 22.8 4.5 0.00041 20.3 0.5 2.4 2 0 0 2 2 2 1 Double zinc ribbon zinc_ribbon_15 PF17032.5 EGC36627.1 - 0.0028 18.3 0.5 0.0028 18.3 0.5 2.3 2 1 0 2 2 2 1 zinc-ribbon family DUF4451 PF14616.6 EGC36627.1 - 0.15 12.3 3.5 0.43 10.8 3.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4451) zf-ribbon_3 PF13248.6 EGC36627.1 - 0.81 9.2 9.8 5.1 6.7 0.3 2.6 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_2 PF13240.6 EGC36627.1 - 1.1 9.0 14.6 0.55 10.0 5.6 3.0 3 1 0 3 3 3 0 zinc-ribbon domain PGM_PMM_I PF02878.16 EGC36628.1 - 9.3e-29 99.9 0.0 5.1e-28 97.5 0.0 2.2 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.16 EGC36628.1 - 5.6e-24 84.7 0.0 1.3e-23 83.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.16 EGC36628.1 - 2.2e-17 63.3 0.0 4.7e-17 62.2 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.20 EGC36628.1 - 2.2e-07 31.0 0.0 6.5e-07 29.4 0.0 1.8 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1947 PF09183.10 EGC36629.1 - 0.26 11.6 0.1 0.26 11.6 0.1 4.1 3 1 1 4 4 4 0 Domain of unknown function (DUF1947) ComC PF03047.14 EGC36629.1 - 2.3 8.1 6.1 0.51 10.2 0.4 2.9 3 0 0 3 3 3 0 COMC family MFS_1 PF07690.16 EGC36630.1 - 1.8e-50 171.9 16.8 4.9e-44 150.7 3.4 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily TORC_C PF12886.7 EGC36630.1 - 0.33 11.5 1.6 0.62 10.7 0.1 2.3 3 0 0 3 3 3 0 Transducer of regulated CREB activity, C terminus PS_Dcarbxylase PF02666.15 EGC36631.1 - 7.9e-58 195.3 0.0 1.3e-57 194.7 0.0 1.3 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.30 EGC36631.1 - 6.8e-27 93.8 0.7 1.4e-26 92.7 0.2 1.9 2 0 0 2 2 2 1 C2 domain EF-hand_1 PF00036.32 EGC36631.1 - 0.00022 20.5 0.1 0.00088 18.7 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.6 EGC36631.1 - 0.00062 20.2 0.7 0.003 18.0 0.5 2.2 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGC36631.1 - 0.0043 16.9 0.0 0.011 15.6 0.0 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC36631.1 - 0.013 15.3 0.4 0.049 13.6 0.1 2.2 2 0 0 2 2 2 0 EF-hand domain DEAD PF00270.29 EGC36632.1 - 3e-33 115.0 13.4 4.3e-33 114.6 8.0 3.3 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC36632.1 - 2.4e-28 98.7 5.8 8.5e-28 96.9 0.1 3.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RNA_pol_3_Rpc31 PF11705.8 EGC36632.1 - 0.0021 18.3 12.2 0.0021 18.3 12.2 6.0 4 2 2 6 6 6 2 DNA-directed RNA polymerase III subunit Rpc31 BOP1NT PF08145.12 EGC36633.1 - 3.4e-96 322.2 7.8 7.3e-96 321.1 7.8 1.6 1 0 0 1 1 1 1 BOP1NT (NUC169) domain WD40 PF00400.32 EGC36633.1 - 2.9e-23 81.7 5.3 1.1e-09 38.7 0.1 7.0 6 1 1 7 7 7 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36633.1 - 4.6e-07 30.0 0.1 0.0001 22.6 0.1 3.8 3 1 1 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain Coatomer_WDAD PF04053.14 EGC36633.1 - 0.06 12.4 3.4 1.9 7.4 0.1 2.6 3 0 0 3 3 3 0 Coatomer WD associated region BUD22 PF09073.10 EGC36633.1 - 3 7.1 33.0 0.3 10.4 28.5 1.6 2 0 0 2 2 2 0 BUD22 La PF05383.17 EGC36634.1 - 1.1e-07 31.8 0.1 3e-07 30.4 0.1 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGC36634.1 - 2.2e-05 24.2 0.1 0.0017 18.1 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC36634.1 - 0.015 15.3 0.4 0.062 13.4 0.1 2.3 2 0 0 2 2 2 0 RNA binding motif Arm_3 PF16186.5 EGC36634.1 - 0.02 14.4 0.9 0.02 14.4 0.9 2.4 2 0 0 2 2 2 0 Atypical Arm repeat GATA PF00320.27 EGC36635.1 - 3.2e-15 55.4 2.7 3.2e-15 55.4 2.7 1.9 2 0 0 2 2 2 1 GATA zinc finger PriA_CRR PF18319.1 EGC36635.1 - 0.019 14.9 0.6 0.019 14.9 0.6 2.0 2 0 0 2 2 2 0 PriA DNA helicase Cys-rich region (CRR) domain TFIIA PF03153.13 EGC36635.1 - 0.024 14.7 11.8 0.031 14.3 11.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Ndc1_Nup PF09531.10 EGC36635.1 - 5.8 5.5 8.3 6.4 5.3 8.3 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Menin PF05053.13 EGC36635.1 - 5.9 5.1 7.7 8.7 4.6 7.7 1.3 1 0 0 1 1 1 0 Menin NST1 PF13945.6 EGC36635.1 - 6.9 6.7 19.0 0.68 10.0 13.4 1.9 2 0 0 2 2 2 0 Salt tolerance down-regulator RlaP PF10127.9 EGC36636.1 - 1.9e-18 67.0 0.0 2e-11 44.0 0.0 3.5 3 1 0 3 3 3 3 RNA repair pathway DNA polymerase beta family SKICH PF17751.1 EGC36636.1 - 0.22 12.1 4.3 2.4 8.8 0.2 3.5 2 1 1 4 4 4 0 SKICH domain 6PF2K PF01591.18 EGC36637.1 - 3.3e-68 229.3 0.1 4.3e-68 228.9 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.22 EGC36637.1 - 4.6e-31 108.0 0.0 1.3e-30 106.5 0.0 1.7 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.6 EGC36637.1 - 9e-05 22.7 0.1 0.00027 21.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AIP3 PF03915.13 EGC36637.1 - 0.00096 18.3 0.1 0.0016 17.6 0.1 1.3 1 0 0 1 1 1 1 Actin interacting protein 3 KTI12 PF08433.10 EGC36637.1 - 0.06 12.8 0.1 0.13 11.7 0.1 1.6 1 1 0 1 1 1 0 Chromatin associated protein KTI12 Zeta_toxin PF06414.12 EGC36637.1 - 0.063 12.5 0.1 0.16 11.2 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin SSV1_ORF_D-335 PF07935.11 EGC36638.1 - 0.028 14.7 0.1 0.11 12.8 0.1 2.0 1 0 0 1 1 1 0 ORF D-335-like protein POX PF07526.11 EGC36638.1 - 4.1 8.0 7.4 2.6 8.6 0.6 2.6 2 0 0 2 2 2 0 Associated with HOX Presenilin PF01080.17 EGC36639.1 - 0.19 10.5 5.8 0.3 9.8 5.8 1.3 1 0 0 1 1 1 0 Presenilin DUF4614 PF15391.6 EGC36639.1 - 0.3 11.1 13.3 0.52 10.3 13.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Miga PF10265.9 EGC36639.1 - 3 6.7 14.5 5.3 5.9 13.2 1.7 1 1 1 2 2 2 0 Mitoguardin SPX PF03105.19 EGC36639.1 - 5.3 6.9 17.7 7.4 6.4 17.7 1.1 1 0 0 1 1 1 0 SPX domain MID_MedPIWI PF18296.1 EGC36639.1 - 5.4 6.7 12.9 9.3 6.0 12.9 1.4 1 1 0 1 1 1 0 MID domain of medPIWI DGCR6 PF07324.11 EGC36640.1 - 8.4e-10 38.6 9.9 8.4e-10 38.6 9.9 2.9 3 0 0 3 3 3 1 DiGeorge syndrome critical region 6 (DGCR6) protein RNA_pol_Rpc4 PF05132.14 EGC36640.1 - 0.0054 17.2 0.5 0.0054 17.2 0.5 3.5 3 0 0 3 3 3 2 RNA polymerase III RPC4 Bot1p PF12298.8 EGC36641.1 - 0.00011 22.4 0.0 0.00033 20.9 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.7 EGC36641.1 - 0.0022 18.2 0.4 0.0064 16.7 0.0 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 FTHFS PF01268.19 EGC36642.1 - 1.8e-264 878.1 0.1 2e-264 877.9 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase CbiA PF01656.23 EGC36642.1 - 0.073 13.1 0.0 0.31 11.1 0.0 2.3 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain BAR_3 PF16746.5 EGC36642.1 - 0.11 12.2 0.0 0.16 11.6 0.0 1.2 1 0 0 1 1 1 0 BAR domain of APPL family Thymidylate_kin PF02223.17 EGC36643.1 - 1.5e-42 145.4 0.0 1.7e-42 145.2 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.6 EGC36643.1 - 0.0069 16.6 0.0 0.012 15.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain PPK2 PF03976.14 EGC36643.1 - 0.067 12.7 0.0 0.16 11.4 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) AAA_7 PF12775.7 EGC36643.1 - 0.099 12.1 0.4 1.8 8.0 0.0 2.1 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA_18 PF13238.6 EGC36643.1 - 0.11 13.0 0.0 0.19 12.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC36643.1 - 0.13 12.7 0.0 0.24 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UDPGP PF01704.18 EGC36644.1 - 1.3e-48 165.7 0.0 1.7e-48 165.3 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.7 EGC36644.1 - 0.064 13.6 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain FNIP PF05725.12 EGC36646.1 - 1.4e-45 153.2 15.4 2.9e-10 40.2 0.5 7.3 5 1 4 9 9 9 8 FNIP Repeat DUF4234 PF14018.6 EGC36648.1 - 0.16 12.1 8.9 1 9.5 5.2 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) FNIP PF05725.12 EGC36649.1 - 6.8e-38 128.6 72.0 0.00029 20.9 0.1 12.8 6 2 1 12 12 12 11 FNIP Repeat zf-B_box PF00643.24 EGC36649.1 - 0.0025 17.9 1.3 0.005 17.0 1.3 1.5 1 0 0 1 1 1 1 B-box zinc finger UCH PF00443.29 EGC36650.1 - 1.1e-41 143.1 22.5 1.1e-41 143.1 22.5 2.8 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC36650.1 - 1.8e-20 73.8 19.4 1.8e-20 73.8 19.4 2.8 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGC36650.1 - 4.1e-09 36.9 12.6 2.6e-06 27.9 4.3 7.9 7 2 0 7 7 7 3 DUSP domain Ubiquitin_2 PF14560.6 EGC36650.1 - 0.009 16.4 2.6 0.12 12.8 0.2 3.4 3 0 0 3 3 3 1 Ubiquitin-like domain GFA PF04828.14 EGC36650.1 - 1.6 9.1 6.5 3.2 8.1 3.1 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Profilin PF00235.19 EGC36651.1 - 8.1e-10 39.0 0.0 1.2e-09 38.5 0.0 1.2 1 0 0 1 1 1 1 Profilin AF-4 PF05110.13 EGC36651.1 - 0.13 10.3 2.8 0.13 10.3 2.8 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Dimer_Tnp_hAT PF05699.14 EGC36652.1 - 4.1e-13 48.9 0.3 9.6e-13 47.7 0.3 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region MCM3AP_GANP PF16769.5 EGC36652.1 - 0.0017 16.7 2.3 0.0021 16.4 2.3 1.1 1 0 0 1 1 1 1 MCM3AP domain of GANP RICTOR_N PF14664.6 EGC36652.1 - 0.014 14.4 0.6 0.15 11.0 0.7 2.0 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR, N-term MTBP_C PF14920.6 EGC36652.1 - 0.023 14.5 0.4 0.029 14.1 0.4 1.1 1 0 0 1 1 1 0 MDM2-binding CLN3 PF02487.17 EGC36652.1 - 0.32 10.0 2.7 0.42 9.6 2.7 1.1 1 0 0 1 1 1 0 CLN3 protein Peptidase_S49_N PF08496.10 EGC36652.1 - 0.4 10.7 2.7 0.78 9.8 2.7 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal TraU PF06834.11 EGC36652.1 - 1.2 8.3 3.6 4.2 6.6 0.0 2.1 1 1 1 2 2 2 0 TraU protein FNIP PF05725.12 EGC36653.1 - 2.6e-23 81.9 23.5 7.1e-07 29.3 2.6 5.9 2 1 4 7 7 7 7 FNIP Repeat Pro_isomerase PF00160.21 EGC36653.1 - 0.1 12.8 0.0 55 4.0 0.0 3.0 3 0 0 3 3 3 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thaumatin PF00314.17 EGC36653.1 - 0.33 10.5 0.0 33 4.0 0.0 3.1 1 1 1 2 2 2 0 Thaumatin family SNRNP27 PF08648.12 EGC36653.1 - 0.35 11.0 6.7 46 4.2 0.1 4.0 4 0 0 4 4 4 0 U4/U6.U5 small nuclear ribonucleoproteins FNIP PF05725.12 EGC36654.1 - 0.19 11.9 54.2 0.076 13.2 1.2 10.4 7 4 1 8 8 8 0 FNIP Repeat NST1 PF13945.6 EGC36654.1 - 6 6.9 28.9 1.8 8.6 10.2 2.4 2 0 0 2 2 2 0 Salt tolerance down-regulator DUF4145 PF13643.6 EGC36655.1 - 0.045 13.9 0.0 0.084 13.0 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) PUF PF00806.19 EGC36656.1 - 6e-20 69.7 5.4 0.00091 18.8 0.0 8.1 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat UPF0225 PF17775.1 EGC36656.1 - 0.006 17.4 0.7 0.039 14.8 0.7 2.5 1 0 0 1 1 1 1 UPF0225 domain Telomere_reg-2 PF10193.9 EGC36656.1 - 0.013 15.9 0.3 4 7.9 0.1 2.9 2 0 0 2 2 2 0 Telomere length regulation protein UCH PF00443.29 EGC36657.1 - 8.2e-47 159.9 38.3 2e-44 152.0 38.3 2.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC36657.1 - 2.7e-12 46.9 42.9 1.8e-10 41.0 42.9 3.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Pex14_N PF04695.13 EGC36657.1 - 0.12 13.1 17.0 0.082 13.6 10.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region VIT1 PF01988.19 EGC36657.1 - 0.34 10.7 4.7 0.92 9.3 0.6 2.1 2 0 0 2 2 2 0 VIT family UPF0524 PF15823.5 EGC36658.1 - 1.5 8.2 9.7 2.9 7.2 1.3 2.4 2 0 0 2 2 2 0 UPF0524 of C3orf70 CSRNP_N PF16019.5 EGC36658.1 - 7.2 6.5 11.0 1.4 8.8 1.4 2.2 2 0 0 2 2 2 0 Cysteine/serine-rich nuclear protein N-terminus NUDIX PF00293.28 EGC36659.1 - 1.2e-19 70.7 0.1 1.7e-19 70.1 0.1 1.3 1 0 0 1 1 1 1 NUDIX domain FNIP PF05725.12 EGC36660.1 - 1.4e-51 172.4 84.1 8.5e-06 25.8 1.0 16.9 4 2 13 20 20 20 18 FNIP Repeat zf-B_box PF00643.24 EGC36660.1 - 0.00068 19.7 5.1 0.0012 18.9 5.1 1.4 1 0 0 1 1 1 1 B-box zinc finger AAA_3 PF07726.11 EGC36660.1 - 0.017 15.0 11.5 16 5.4 0.0 7.8 2 2 9 11 11 11 0 ATPase family associated with various cellular activities (AAA) FNIP PF05725.12 EGC36661.1 - 6.1e-29 99.9 53.8 0.00012 22.2 0.0 11.6 4 2 7 14 14 14 12 FNIP Repeat zf-B_box PF00643.24 EGC36661.1 - 0.00049 20.2 5.1 0.00088 19.4 5.1 1.4 1 0 0 1 1 1 1 B-box zinc finger Inhibitor_G39P PF11417.8 EGC36662.1 - 0.068 13.7 0.2 0.068 13.7 0.2 2.3 2 0 0 2 2 2 0 Loader and inhibitor of phage G40P DUF2387 PF09526.10 EGC36662.1 - 7.5 6.8 6.6 5.6 7.2 2.4 2.6 1 1 2 3 3 3 0 Probable metal-binding protein (DUF2387) Glyco_hydro_18 PF00704.28 EGC36663.1 - 6.7e-21 75.3 0.7 9.2e-21 74.9 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 GluR_Homer-bdg PF10606.9 EGC36663.1 - 0.036 14.2 0.3 7.6 6.8 0.0 3.4 3 0 0 3 3 3 0 Homer-binding domain of metabotropic glutamate receptor Phage_Gp17 PF17549.2 EGC36663.1 - 0.13 12.3 0.0 0.26 11.3 0.0 1.4 1 0 0 1 1 1 0 Gene Product 17 Pkinase PF00069.25 EGC36664.1 - 6.6e-73 245.3 0.0 1.3e-72 244.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36664.1 - 7.9e-52 176.1 0.0 1.4e-51 175.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC36664.1 - 8.8e-06 24.7 0.0 8.8e-06 24.7 0.0 2.7 2 1 0 2 2 2 1 Fungal protein kinase ABC1 PF03109.16 EGC36664.1 - 0.018 15.2 0.0 0.044 13.9 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Acyl-CoA_dh_1 PF00441.24 EGC36665.1 - 2.1e-27 96.2 0.1 3e-27 95.7 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGC36665.1 - 2.2e-21 75.9 0.0 3.4e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.16 EGC36665.1 - 3.4e-16 59.9 0.0 5.5e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.11 EGC36665.1 - 1.5e-08 35.0 0.0 2.5e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Brr6_like_C_C PF10104.9 EGC36666.1 - 3.8e-24 85.0 0.4 3.8e-24 85.0 0.4 1.6 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain LMBR1 PF04791.16 EGC36666.1 - 0.45 9.4 7.3 0.6 8.9 7.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Macoilin PF09726.9 EGC36666.1 - 0.54 8.8 20.2 0.61 8.6 20.2 1.1 1 0 0 1 1 1 0 Macoilin family SID-1_RNA_chan PF13965.6 EGC36666.1 - 3.7 5.8 11.9 11 4.3 7.6 2.0 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 FNIP PF05725.12 EGC36667.1 - 1e-21 76.8 25.5 6.8e-09 35.7 0.5 7.4 4 2 5 10 10 10 6 FNIP Repeat zf-B_box PF00643.24 EGC36667.1 - 4e-05 23.7 3.8 7.5e-05 22.8 3.8 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF4940 PF16298.5 EGC36667.1 - 0.00089 19.0 5.8 0.0014 18.4 5.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4940) zf-UBR PF02207.20 EGC36667.1 - 0.011 15.9 1.9 0.021 15.0 1.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Sigma_reg_C PF13791.6 EGC36667.1 - 6.7 6.9 8.9 0.9 9.7 3.8 2.0 1 1 1 2 2 2 0 Sigma factor regulator C-terminal Mito_carr PF00153.27 EGC36668.1 - 1.6e-23 82.4 0.1 3.7e-11 42.8 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein HycH PF07450.11 EGC36668.1 - 0.18 12.2 0.2 0.39 11.1 0.2 1.6 2 0 0 2 2 2 0 Formate hydrogenlyase maturation protein HycH Pkinase PF00069.25 EGC36669.1 - 5.6e-68 229.2 0.0 1.2e-67 228.0 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36669.1 - 1.1e-52 178.9 0.0 1.8e-52 178.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC36669.1 - 1.3e-07 30.8 0.2 1.3e-07 30.8 0.2 3.1 2 2 0 2 2 2 1 Fungal protein kinase BUD22 PF09073.10 EGC36669.1 - 0.0012 18.3 17.7 0.0012 18.3 17.7 4.5 3 1 0 4 4 4 1 BUD22 Kinase-like PF14531.6 EGC36669.1 - 0.0016 17.8 0.0 0.004 16.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like PBD PF00786.28 EGC36669.1 - 0.014 15.7 0.1 0.11 12.9 0.1 2.7 1 0 0 1 1 1 0 P21-Rho-binding domain SAM_KSR1 PF13543.6 EGC36669.1 - 0.38 10.9 4.3 1 9.5 4.3 1.6 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Glucokinase PF02685.16 EGC36671.1 - 1.3e-23 83.5 0.0 1.7e-23 83.1 0.0 1.1 1 0 0 1 1 1 1 Glucokinase ROK PF00480.20 EGC36671.1 - 0.00087 18.9 0.2 0.054 13.0 0.0 2.2 2 0 0 2 2 2 2 ROK family Hydant_A_N PF05378.13 EGC36671.1 - 0.13 11.9 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase N-terminal region BcrAD_BadFG PF01869.20 EGC36671.1 - 0.18 11.3 0.0 0.41 10.1 0.0 1.5 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family AAA PF00004.29 EGC36672.1 - 5.2e-52 175.8 0.7 5.4e-42 143.3 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.25 EGC36672.1 - 1.5e-14 53.8 1.3 7.6e-14 51.5 1.3 2.3 1 0 0 1 1 1 1 Bromodomain AAA_lid_3 PF17862.1 EGC36672.1 - 2.2e-09 37.0 0.0 6.1e-09 35.6 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain IstB_IS21 PF01695.17 EGC36672.1 - 9.4e-07 28.7 0.0 3.5e-05 23.6 0.0 3.1 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.6 EGC36672.1 - 0.00044 20.7 0.0 0.00044 20.7 0.0 2.9 3 0 0 3 3 2 1 AAA ATPase domain AAA_5 PF07728.14 EGC36672.1 - 0.008 16.2 0.7 0.08 12.9 0.1 3.1 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGC36672.1 - 0.0086 15.8 0.0 0.031 14.0 0.0 2.0 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC36672.1 - 0.027 14.7 4.5 0.17 12.2 0.5 3.7 3 1 0 3 3 2 0 AAA domain AAA_33 PF13671.6 EGC36672.1 - 0.035 14.3 0.0 0.21 11.8 0.0 2.4 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGC36672.1 - 0.038 13.4 0.0 0.13 11.6 0.0 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGC36672.1 - 0.075 12.9 0.1 0.35 10.8 0.0 2.2 2 0 0 2 2 2 0 NACHT domain DUF4894 PF16235.5 EGC36672.1 - 0.99 9.8 9.6 0.031 14.7 1.4 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4894) DUF2039 PF10217.9 EGC36673.1 - 1.1e-25 89.8 12.2 1.1e-25 89.8 12.2 2.5 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2039) zinc-ribbons_6 PF07191.12 EGC36673.1 - 0.00084 19.3 7.3 0.0017 18.3 7.3 1.5 1 0 0 1 1 1 1 zinc-ribbons Paired_CXXCH_1 PF09699.10 EGC36673.1 - 0.0069 16.1 9.0 0.011 15.4 0.7 2.8 2 0 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) DZR PF12773.7 EGC36673.1 - 0.017 15.1 9.3 0.11 12.5 7.0 2.3 2 0 0 2 2 2 0 Double zinc ribbon Cript PF10235.9 EGC36673.1 - 0.03 14.9 10.8 0.03 14.9 10.8 2.8 2 2 1 3 3 3 0 Microtubule-associated protein CRIPT MCR PF18509.1 EGC36673.1 - 2.7 7.6 5.8 12 5.6 2.0 2.5 2 0 0 2 2 2 0 Magnetochrome domain HypA PF01155.19 EGC36673.1 - 5.8 7.0 8.9 0.67 10.0 0.6 2.5 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Ribosomal_L17 PF01196.19 EGC36674.1 - 3.6e-31 107.9 2.4 5.1e-31 107.4 2.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 SET PF00856.28 EGC36675.1 - 1.6e-11 44.9 0.0 1.6e-11 44.9 0.0 4.2 4 2 0 4 4 4 1 SET domain Rubis-subs-bind PF09273.11 EGC36675.1 - 3.2e-10 40.8 14.0 9.9e-08 32.7 0.0 4.7 5 0 0 5 5 5 2 Rubisco LSMT substrate-binding Med6 PF04934.14 EGC36675.1 - 0.04 13.7 8.1 0.11 12.3 1.0 3.2 2 0 0 2 2 2 0 MED6 mediator sub complex component CytochromB561_N PF09786.9 EGC36676.1 - 1.4e-14 54.0 2.1 1.4e-14 54.0 2.1 3.1 3 0 0 3 3 3 2 Cytochrome B561, N terminal DUF445 PF04286.12 EGC36677.1 - 0.0032 17.3 14.5 0.0032 17.3 14.5 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF445) DUF2621 PF11084.8 EGC36677.1 - 0.041 13.8 1.8 0.17 11.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2621) DUF4834 PF16118.5 EGC36677.1 - 0.075 14.0 0.2 0.075 14.0 0.2 8.4 3 2 0 3 3 3 0 Domain of unknown function (DUF4834) Hormone_3 PF00159.18 EGC36677.1 - 7.8 6.7 6.8 16 5.7 0.1 3.3 4 0 0 4 4 4 0 Pancreatic hormone peptide ABC_tran PF00005.27 EGC36678.1 - 1.5e-27 96.8 0.0 2.4e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC36678.1 - 1e-05 25.5 2.1 0.00093 19.1 0.1 2.2 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC36678.1 - 0.0011 19.4 0.1 0.0016 18.9 0.1 1.5 1 1 0 1 1 1 1 AAA ATPase domain Rad17 PF03215.15 EGC36678.1 - 0.002 18.1 0.0 0.0049 16.8 0.0 1.4 1 1 0 1 1 1 1 Rad17 P-loop domain RsgA_GTPase PF03193.16 EGC36678.1 - 0.0021 18.0 0.1 0.0058 16.6 0.0 1.7 2 0 0 2 2 2 1 RsgA GTPase SbcCD_C PF13558.6 EGC36678.1 - 0.0049 17.1 0.2 0.092 13.0 0.2 2.4 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit SMC_N PF02463.19 EGC36678.1 - 0.015 14.7 0.3 0.43 10.0 0.0 2.1 1 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.12 EGC36678.1 - 0.065 13.1 0.6 4.1 7.3 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 EGC36678.1 - 0.11 12.3 0.0 0.22 11.3 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain HCNGP PF07818.13 EGC36679.1 - 6.9e-27 93.9 0.1 6.9e-27 93.9 0.1 2.6 2 0 0 2 2 2 1 HCNGP-like protein DUF4758 PF15950.5 EGC36679.1 - 2 8.8 10.1 0.14 12.5 0.5 2.5 2 0 0 2 2 2 0 Putative sperm flagellar membrane protein DUF4578 PF15147.6 EGC36679.1 - 2.3 9.1 11.3 2.2 9.2 9.6 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4578) zf-TRAF PF02176.18 EGC36681.1 - 4.1e-11 43.4 18.9 1.9e-10 41.3 4.5 4.3 2 2 3 5 5 5 3 TRAF-type zinc finger Sina PF03145.16 EGC36681.1 - 0.00089 19.3 12.2 0.023 14.6 1.2 3.7 1 1 2 3 3 3 2 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC36681.1 - 0.08 13.4 25.2 0.049 14.1 5.8 3.8 1 1 2 4 4 4 0 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 EGC36681.1 - 0.48 10.3 22.7 0.08 12.8 11.4 2.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC36681.1 - 5.4 7.0 20.2 0.54 10.1 14.4 2.5 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Attachment_P66 PF11263.8 EGC36682.1 - 0.0028 17.0 0.2 0.0061 15.9 0.2 1.5 1 0 0 1 1 1 1 Borrelia burgdorferi attachment protein P66 DUF2121 PF09894.9 EGC36682.1 - 0.13 11.8 1.0 0.22 11.1 0.2 1.7 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2121) Beach PF02138.18 EGC36683.1 - 4.2e-39 134.6 1.2 1.3e-38 133.0 1.1 2.0 1 1 0 1 1 1 1 Beige/BEACH domain Pkinase PF00069.25 EGC36683.1 - 1.3e-10 41.1 6.7 4.4e-06 26.2 0.0 2.8 3 0 0 3 3 3 2 Protein kinase domain WD40 PF00400.32 EGC36683.1 - 4.2e-07 30.6 2.5 0.037 14.9 0.0 5.6 5 0 0 5 5 5 1 WD domain, G-beta repeat Kinase-like PF14531.6 EGC36683.1 - 0.00014 21.3 0.0 0.00029 20.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like ANAPC4_WD40 PF12894.7 EGC36683.1 - 0.00019 21.7 0.0 3.2 8.1 0.0 3.6 3 0 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain Pkinase_Tyr PF07714.17 EGC36683.1 - 0.11 11.7 0.0 0.39 10.0 0.0 1.8 2 0 0 2 2 2 0 Protein tyrosine kinase NPH3 PF03000.14 EGC36683.1 - 3.2 7.3 5.6 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 NPH3 family DUF3053 PF11254.8 EGC36684.1 - 0.055 13.0 0.0 0.061 12.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) EF-hand_1 PF00036.32 EGC36686.1 - 2.5e-12 45.4 5.3 0.0042 16.5 0.3 3.8 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.6 EGC36686.1 - 2.9e-12 45.5 1.2 0.0012 18.6 0.1 3.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGC36686.1 - 1.1e-10 41.8 9.6 3.5e-05 24.2 1.2 2.5 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC36686.1 - 1.4e-06 27.5 0.2 0.72 9.4 0.0 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.6 EGC36686.1 - 3.1e-05 23.7 0.5 0.49 10.3 0.0 3.4 4 0 0 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC36686.1 - 0.0033 17.7 5.1 0.98 9.8 1.5 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_13 PF17958.1 EGC36686.1 - 0.025 14.4 0.0 4.7 7.1 0.0 2.4 2 1 0 2 2 2 0 EF-hand domain ZFYVE21_C PF16696.5 EGC36686.1 - 0.042 13.7 0.2 0.15 11.9 0.1 1.9 1 1 1 2 2 2 0 Zinc finger FYVE domain-containing protein 21 C-terminus Phage_int_SAM_4 PF13495.6 EGC36686.1 - 0.06 13.8 0.1 8.5 6.9 0.0 2.4 2 0 0 2 2 2 0 Phage integrase, N-terminal SAM-like domain Caleosin PF05042.13 EGC36686.1 - 0.072 13.0 0.5 13 5.7 0.1 2.5 1 1 0 2 2 2 0 Caleosin related protein Med4 PF10018.9 EGC36686.1 - 0.086 12.5 0.0 0.16 11.6 0.0 1.4 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 PTS-HPr PF00381.19 EGC36687.1 - 7e-16 58.2 0.1 7.8e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site Mfa_like_2 PF15415.6 EGC36687.1 - 0.068 12.0 0.0 0.072 12.0 0.0 1.1 1 0 0 1 1 1 0 Fimbrillin-like INCENP_ARK-bind PF03941.15 EGC36688.1 - 5.4e-08 32.6 0.3 5.4e-08 32.6 0.3 5.9 5 0 0 5 5 5 1 Inner centromere protein, ARK binding region Dickkopf_N PF04706.12 EGC36690.1 - 0.0082 16.6 12.2 0.0082 16.6 12.2 6.7 3 2 4 7 7 7 4 Dickkopf N-terminal cysteine-rich region Ubie_methyltran PF01209.18 EGC36691.1 - 3.7e-22 78.8 0.3 3.2e-20 72.5 0.3 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGC36691.1 - 6e-18 65.3 0.0 1.2e-17 64.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36691.1 - 6.5e-18 65.0 0.4 1.5e-17 63.8 0.0 1.7 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36691.1 - 1e-14 54.7 0.0 1.5e-14 54.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36691.1 - 5.7e-14 52.5 0.0 9.5e-14 51.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36691.1 - 5.4e-10 39.9 0.0 1.2e-09 38.8 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain TehB PF03848.14 EGC36691.1 - 0.00024 20.6 0.0 0.00039 19.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 EGC36691.1 - 0.00035 20.4 0.0 0.00079 19.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF938) PCMT PF01135.19 EGC36691.1 - 0.002 17.9 0.0 0.0048 16.7 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.13 EGC36691.1 - 0.0022 17.5 0.3 0.034 13.6 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.7 EGC36691.1 - 0.0022 17.9 0.1 0.0063 16.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGC36691.1 - 0.0034 16.9 0.0 0.013 15.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain DREV PF05219.12 EGC36691.1 - 0.017 14.3 0.0 0.029 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase Methyltr_RsmB-F PF01189.17 EGC36691.1 - 0.057 13.1 0.0 0.15 11.7 0.0 1.6 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F PA28_alpha PF02251.18 EGC36691.1 - 0.065 13.3 0.1 0.25 11.4 0.0 2.1 2 0 0 2 2 1 0 Proteasome activator pa28 alpha subunit Methyltransf_4 PF02390.17 EGC36691.1 - 0.079 12.4 0.2 1.1 8.7 0.1 2.7 1 1 1 2 2 2 0 Putative methyltransferase Methyltransf_20 PF12147.8 EGC36691.1 - 0.096 11.8 0.0 0.18 10.9 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_3 PF01596.17 EGC36691.1 - 0.1 11.7 1.0 1.8 7.7 0.2 2.2 2 0 0 2 2 2 0 O-methyltransferase Leukocidin PF07968.12 EGC36691.1 - 0.11 12.4 2.0 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Leukocidin/Hemolysin toxin family Methyltransf_8 PF05148.15 EGC36691.1 - 0.13 12.1 0.2 4.8 7.0 0.0 2.5 1 1 0 2 2 2 0 Hypothetical methyltransferase Ubie_methyltran PF01209.18 EGC36692.1 - 6.9e-21 74.6 0.4 4.4e-19 68.8 0.4 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGC36692.1 - 2.8e-18 66.4 0.0 6.6e-18 65.2 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36692.1 - 5.5e-18 65.2 0.1 2.8e-17 62.9 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36692.1 - 1.9e-14 54.0 0.0 3.2e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC36692.1 - 5.7e-14 52.3 0.0 8.2e-14 51.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36692.1 - 3e-10 40.7 0.1 8.7e-10 39.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.14 EGC36692.1 - 0.00014 21.3 0.1 0.0002 20.8 0.1 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB DUF938 PF06080.12 EGC36692.1 - 0.00026 20.8 0.0 0.00042 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.19 EGC36692.1 - 0.0019 18.0 0.0 0.0033 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.14 EGC36692.1 - 0.0021 17.6 0.0 0.007 15.9 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGC36692.1 - 0.0028 17.6 0.0 0.0058 16.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EGC36692.1 - 0.0073 15.4 0.0 0.013 14.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.13 EGC36692.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.17 EGC36692.1 - 0.021 14.3 0.1 0.25 10.8 0.1 2.5 2 1 0 2 2 2 0 Putative methyltransferase Methyltr_RsmB-F PF01189.17 EGC36692.1 - 0.032 13.9 0.0 0.11 12.2 0.0 1.8 2 0 0 2 2 2 0 16S rRNA methyltransferase RsmB/F Methyltransf_20 PF12147.8 EGC36692.1 - 0.042 13.0 0.0 0.064 12.4 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Leukocidin PF07968.12 EGC36692.1 - 0.048 13.6 0.1 0.079 12.9 0.1 1.2 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family PA28_alpha PF02251.18 EGC36692.1 - 0.074 13.1 0.0 0.28 11.2 0.0 2.0 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Methyltransf_16 PF10294.9 EGC36692.1 - 0.12 12.1 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Lysine methyltransferase Met_10 PF02475.16 EGC36692.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein NST1 PF13945.6 EGC36693.1 - 4.5e-45 154.1 17.1 4.5e-45 154.1 17.1 12.8 5 4 9 14 14 14 3 Salt tolerance down-regulator Aminotran_3 PF00202.21 EGC36694.1 - 2.8e-113 378.7 0.0 3.2e-113 378.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-III Fer4_7 PF12838.7 EGC36694.1 - 0.18 12.4 1.6 0.46 11.1 1.6 1.7 1 0 0 1 1 1 0 4Fe-4S dicluster domain Pkinase PF00069.25 EGC36695.1 - 1.4e-58 198.3 0.0 1.9e-58 197.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36695.1 - 4.8e-38 130.9 0.0 6.4e-38 130.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC36695.1 - 2.9e-10 40.0 0.0 4.5e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGC36695.1 - 0.023 13.5 0.1 0.072 11.9 0.0 1.7 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EGC36695.1 - 0.061 13.2 0.0 1.3 8.9 0.1 2.1 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.14 EGC36695.1 - 0.14 11.5 0.0 0.19 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MitMem_reg PF13012.6 EGC36696.1 - 7.3e-32 110.1 2.6 1.2e-31 109.4 2.6 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGC36696.1 - 4.4e-30 104.1 0.0 2.9e-29 101.4 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF4778 PF16008.5 EGC36696.1 - 0.035 14.2 0.7 0.053 13.6 0.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4778) DUF2999 PF11212.8 EGC36696.1 - 0.037 14.3 0.1 0.12 12.7 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) ABC_tran PF00005.27 EGC36698.1 - 3.8e-31 108.4 0.0 3.8e-31 108.4 0.0 2.4 2 1 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGC36698.1 - 0.00076 19.4 0.1 0.00076 19.4 0.1 2.8 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system SbcCD_C PF13558.6 EGC36698.1 - 0.098 12.9 1.5 1.6 9.0 0.2 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UPF0697 PF15117.6 EGC36698.1 - 0.2 11.7 0.1 0.2 11.7 0.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0697 AAA_28 PF13521.6 EGC36698.1 - 0.21 11.8 0.8 0.65 10.2 0.6 1.9 2 0 0 2 2 2 0 AAA domain DUF3678 PF12435.8 EGC36698.1 - 0.39 10.1 3.3 1.1 8.7 0.3 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3678) Nop PF01798.18 EGC36701.1 - 6.9e-83 277.6 0.3 6.9e-83 277.6 0.3 2.4 2 0 0 2 2 2 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGC36701.1 - 2.1e-17 63.3 1.0 2.1e-17 63.3 1.0 3.2 2 1 0 2 2 2 1 NOP5NT (NUC127) domain CDC27 PF09507.10 EGC36701.1 - 0.02 14.3 54.4 0.026 13.9 54.4 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2104 PF09877.9 EGC36701.1 - 0.18 12.0 0.2 1.1 9.5 0.0 2.0 2 0 0 2 2 2 0 Predicted membrane protein (DUF2104) tRNA-synt_2 PF00152.20 EGC36702.1 - 3.6e-95 318.7 0.1 4.3e-95 318.4 0.1 1.0 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGC36702.1 - 2.1e-09 37.2 1.5 3.5e-09 36.5 0.3 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGC36702.1 - 0.014 14.9 0.1 0.74 9.2 0.0 3.0 3 1 0 3 3 3 0 tRNA synthetases class II core domain (F) Csc2 PF18320.1 EGC36702.1 - 0.055 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Csc2 Crispr YjcQ PF09639.10 EGC36703.1 - 0.044 14.0 2.7 0.18 12.0 0.1 2.9 3 0 0 3 3 3 0 YjcQ protein WH2 PF02205.20 EGC36704.1 - 6.2e-11 41.8 1.3 6.2e-11 41.8 1.3 2.3 2 0 0 2 2 2 1 WH2 motif SH3_1 PF00018.28 EGC36704.1 - 2e-07 30.5 0.0 3.5e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC36704.1 - 0.00054 19.8 0.5 0.0014 18.5 0.1 1.8 2 0 0 2 2 2 1 Variant SH3 domain HR1 PF02185.16 EGC36704.1 - 0.0042 17.2 1.4 0.0071 16.4 1.4 1.3 1 0 0 1 1 1 1 Hr1 repeat SlyX PF04102.12 EGC36704.1 - 0.022 15.4 2.8 0.091 13.4 2.8 2.1 1 0 0 1 1 1 0 SlyX DMPK_coil PF08826.10 EGC36704.1 - 0.061 13.4 1.9 0.1 12.7 1.9 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like DUF4140 PF13600.6 EGC36704.1 - 0.069 13.6 0.0 0.12 12.9 0.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) DUF1840 PF08895.11 EGC36706.1 - 0.31 11.4 1.8 1.1 9.6 1.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Pox_polyA_pol_N PF12630.7 EGC36706.1 - 3.2 8.2 11.3 9.4 6.6 0.2 3.0 2 1 1 3 3 3 0 Poxvirus poly(A) polymerase N-terminal domain Bromodomain PF00439.25 EGC36707.1 - 2.3e-07 30.8 0.5 1.3e-06 28.3 0.5 2.4 1 0 0 1 1 1 1 Bromodomain FHA PF00498.26 EGC36707.1 - 0.00055 20.2 0.0 0.0013 19.1 0.0 1.7 1 0 0 1 1 1 1 FHA domain 4HBT_3 PF13622.6 EGC36707.1 - 9.9 6.3 6.2 20 5.3 6.2 1.5 1 0 0 1 1 1 0 Thioesterase-like superfamily Brr6_like_C_C PF10104.9 EGC36708.1 - 0.11 12.2 0.1 0.11 12.2 0.1 1.7 1 1 0 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF4407 PF14362.6 EGC36708.1 - 0.13 11.6 3.4 0.16 11.3 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FliP PF00813.20 EGC36708.1 - 0.77 9.6 2.5 0.74 9.7 1.9 1.3 1 1 0 1 1 1 0 FliP family Presenilin PF01080.17 EGC36708.1 - 4.5 5.9 9.2 4.9 5.8 9.2 1.1 1 0 0 1 1 1 0 Presenilin DUF87 PF01935.17 EGC36708.1 - 5.3 7.1 10.2 9.3 6.3 10.0 1.4 1 1 1 2 2 2 0 Helicase HerA, central domain GLTP PF08718.11 EGC36708.1 - 7.2 6.9 8.1 20 5.4 8.1 1.7 1 1 0 1 1 1 0 Glycolipid transfer protein (GLTP) PAPS_reduct PF01507.19 EGC36709.1 - 4.5e-30 105.0 0.0 5.1e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Plant_vir_prot PF01307.17 EGC36709.1 - 0.00076 19.7 0.2 0.0017 18.5 0.2 1.5 1 0 0 1 1 1 1 Plant viral movement protein AAA PF00004.29 EGC36710.1 - 4.6e-16 59.4 0.1 1.2e-15 58.1 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC36710.1 - 3.8e-10 40.2 0.0 9.3e-10 38.9 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC36710.1 - 1.6e-09 38.4 0.0 6.2e-09 36.5 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_lid_10 PF17872.1 EGC36710.1 - 2.8e-08 33.8 0.3 1.1e-07 31.9 0.1 2.1 2 0 0 2 2 2 1 AAA lid domain NACHT PF05729.12 EGC36710.1 - 9.2e-05 22.4 0.0 0.0002 21.3 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGC36710.1 - 0.00015 21.8 0.1 0.00015 21.8 0.1 2.4 3 0 0 3 3 3 1 ATPase domain predominantly from Archaea AAA_19 PF13245.6 EGC36710.1 - 0.00016 22.0 0.5 0.001 19.4 0.5 2.1 1 1 0 1 1 1 1 AAA domain DUF2075 PF09848.9 EGC36710.1 - 0.0056 16.0 0.0 0.0095 15.2 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AFG1_ATPase PF03969.16 EGC36710.1 - 0.033 13.1 0.0 0.052 12.4 0.0 1.4 1 1 0 1 1 1 0 AFG1-like ATPase AAA_18 PF13238.6 EGC36710.1 - 0.036 14.6 1.1 0.085 13.4 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGC36710.1 - 0.041 13.7 0.0 0.041 13.7 0.0 2.5 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EGC36710.1 - 0.043 13.8 0.3 0.15 12.1 0.3 2.0 1 1 0 1 1 1 0 AAA domain Viral_helicase1 PF01443.18 EGC36710.1 - 0.049 13.4 0.2 0.15 11.8 0.2 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EGC36710.1 - 0.054 13.0 0.0 0.14 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing dynein motor region PIF1 PF05970.14 EGC36710.1 - 0.055 12.6 0.1 0.1 11.7 0.1 1.4 1 0 0 1 1 1 0 PIF1-like helicase TniB PF05621.11 EGC36710.1 - 0.056 12.9 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein NB-ARC PF00931.22 EGC36710.1 - 0.08 12.1 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Sigma54_activat PF00158.26 EGC36710.1 - 0.089 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_5 PF07728.14 EGC36710.1 - 0.11 12.5 0.1 6.7 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NTPase_1 PF03266.15 EGC36710.1 - 0.13 12.2 0.3 0.31 10.9 0.3 1.6 1 0 0 1 1 1 0 NTPase Pro-kuma_activ PF09286.11 EGC36711.1 - 1.5e-27 96.7 0.1 2.6e-27 95.9 0.1 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC36711.1 - 3.2e-06 26.6 0.0 6.5e-05 22.3 0.0 2.1 1 1 0 1 1 1 1 Subtilase family p450 PF00067.22 EGC36713.1 - 1.2e-59 202.3 0.0 1.3e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Arif-1 PF06770.11 EGC36714.1 - 0.021 14.5 0.5 0.021 14.5 0.5 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Glyco_hydro_9 PF00759.19 EGC36716.1 - 1e-85 288.6 6.9 1.2e-85 288.5 6.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Mago-bind PF09282.10 EGC36717.1 - 4.8e-13 48.7 0.0 7.1e-13 48.2 0.0 1.3 1 0 0 1 1 1 1 Mago binding DIOX_N PF14226.6 EGC36718.1 - 4.4e-22 79.1 0.1 7.2e-22 78.4 0.1 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC36718.1 - 6.3e-19 68.3 0.0 1.6e-18 67.1 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3045 PF11243.8 EGC36718.1 - 0.11 12.7 0.7 0.38 10.9 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) FNIP PF05725.12 EGC36719.1 - 3.3e-106 347.2 51.2 1.2e-16 60.6 2.0 7.9 3 2 6 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.13 EGC36719.1 - 9.3e-05 22.8 0.1 31 5.0 0.0 6.3 2 2 4 7 7 7 1 Phage minor tail protein COA2 PF17051.5 EGC36719.1 - 5 7.3 6.6 6.2 6.9 0.1 3.1 4 0 0 4 4 4 0 Cytochrome C oxidase assembly factor 2 Kelch_6 PF13964.6 EGC36720.1 - 8.1e-17 60.8 12.7 0.00011 22.3 0.1 5.6 6 0 0 6 6 6 4 Kelch motif Kelch_3 PF13415.6 EGC36720.1 - 4.3e-16 58.8 9.6 0.00016 21.9 0.1 6.4 6 0 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.6 EGC36720.1 - 3.9e-15 55.6 13.3 1.4e-06 28.2 0.1 5.5 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC36720.1 - 9.6e-13 47.8 8.4 0.022 14.8 0.1 5.9 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGC36720.1 - 5.3e-10 38.7 7.7 0.19 11.4 0.2 5.3 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.15 EGC36720.1 - 1.6e-06 27.8 15.1 0.0034 17.3 0.5 5.6 5 1 0 5 5 5 3 Kelch motif SNARE PF05739.19 EGC36721.1 - 1.7e-08 34.3 5.1 2.9e-08 33.6 3.0 2.2 2 0 0 2 2 2 1 SNARE domain Syntaxin_2 PF14523.6 EGC36721.1 - 7.4e-07 29.5 8.4 7.4e-07 29.5 8.4 2.8 1 1 2 3 3 3 1 Syntaxin-like protein Glyco_hydro_57 PF03065.15 EGC36721.1 - 0.052 12.7 0.7 0.11 11.7 0.1 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 57 Fez1 PF06818.15 EGC36721.1 - 0.48 10.8 12.9 0.14 12.6 2.3 2.4 1 1 1 2 2 2 0 Fez1 SPT16 PF08644.11 EGC36721.1 - 1.5 9.0 7.9 0.18 12.0 1.5 2.3 2 1 0 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF2203 PF09969.9 EGC36721.1 - 6.2 7.6 9.8 4.5 8.0 0.5 3.0 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) RhoGEF PF00621.20 EGC36722.1 - 1.6e-47 162.1 10.9 1.6e-47 162.1 10.9 2.3 3 0 0 3 3 2 1 RhoGEF domain PH PF00169.29 EGC36722.1 - 2e-27 95.7 12.2 1.4e-16 60.9 2.1 3.7 3 1 0 3 3 3 2 PH domain ArfGap PF01412.18 EGC36722.1 - 2e-21 76.2 1.1 2e-21 76.2 1.1 2.4 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CH PF00307.31 EGC36722.1 - 6.2e-18 65.0 1.3 1.5e-17 63.7 0.1 2.3 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_9 PF15410.6 EGC36722.1 - 1.8e-05 25.1 5.4 0.0011 19.4 0.3 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain CAMSAP_CH PF11971.8 EGC36722.1 - 0.00042 20.1 0.3 0.0013 18.6 0.0 2.0 2 0 0 2 2 2 1 CAMSAP CH domain PH_2 PF08458.10 EGC36722.1 - 0.0071 16.7 0.4 1.2 9.5 0.3 2.9 2 0 0 2 2 2 1 Plant pleckstrin homology-like region IQ PF00612.27 EGC36722.1 - 0.011 15.5 5.7 0.12 12.2 1.2 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif PH_11 PF15413.6 EGC36722.1 - 0.013 15.9 15.8 0.034 14.6 5.0 4.9 3 2 0 3 3 3 0 Pleckstrin homology domain PH_16 PF17838.1 EGC36722.1 - 0.014 15.2 0.5 0.058 13.2 0.4 2.2 2 0 0 2 2 2 0 PH domain PH_8 PF15409.6 EGC36722.1 - 0.029 14.6 0.4 0.088 13.1 0.4 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.7 EGC36722.1 - 1.2 9.2 6.5 0.28 11.3 0.4 3.0 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology ATG27 PF09451.10 EGC36723.1 - 3.3e-10 40.3 1.5 3.6e-07 30.3 0.4 2.2 1 1 1 2 2 2 2 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGC36723.1 - 4.3e-09 35.8 0.5 6e-09 35.4 0.2 1.4 2 0 0 2 2 2 1 Mannose-6-phosphate receptor CIMR PF00878.18 EGC36723.1 - 0.00042 20.4 0.5 0.00066 19.8 0.5 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat ISK_Channel PF02060.15 EGC36723.1 - 0.032 14.0 0.1 0.053 13.2 0.1 1.4 1 0 0 1 1 1 0 Slow voltage-gated potassium channel Rab5ip PF07019.12 EGC36724.1 - 2.3e-17 63.4 8.1 2.8e-17 63.1 8.1 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) FtsJ PF01728.19 EGC36725.1 - 9.3e-30 104.0 0.0 1.5e-29 103.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.23 EGC36725.1 - 3.1e-09 36.6 0.5 3.1e-09 36.6 0.5 1.7 2 0 0 2 2 2 1 G-patch domain G-patch_2 PF12656.7 EGC36725.1 - 6.1e-06 26.2 0.2 3.3e-05 23.9 0.2 2.4 2 0 0 2 2 2 1 G-patch domain CENP-B_dimeris PF09026.10 EGC36725.1 - 2.8 8.4 12.5 7.8 7.0 12.5 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LETM1 PF07766.13 EGC36726.1 - 5.7e-25 88.2 0.4 5.7e-25 88.2 0.4 2.1 2 0 0 2 2 2 1 LETM1-like protein DUF1957 PF09210.11 EGC36726.1 - 0.0075 16.6 0.6 0.015 15.7 0.3 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1957) UPF0242 PF06785.11 EGC36726.1 - 0.59 10.2 16.7 0.19 11.8 13.7 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus RtcB PF01139.17 EGC36726.1 - 1.1 8.4 5.2 1.5 7.9 5.2 1.1 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB RR_TM4-6 PF06459.12 EGC36726.1 - 3.8 7.3 17.0 4.7 7.0 17.0 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Peptidase_C78 PF07910.13 EGC36727.1 - 3.5e-54 183.5 0.3 6.9e-54 182.5 0.3 1.5 1 0 0 1 1 1 1 Peptidase family C78 bZIP_1 PF00170.21 EGC36728.1 - 0.01 15.9 0.4 0.025 14.7 0.4 1.7 1 0 0 1 1 1 0 bZIP transcription factor RP-C_C PF11800.8 EGC36728.1 - 0.025 14.7 0.3 0.035 14.2 0.3 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region bZIP_2 PF07716.15 EGC36728.1 - 0.078 13.1 1.9 0.17 12.0 1.9 1.5 1 0 0 1 1 1 0 Basic region leucine zipper RNA_polI_A14 PF08203.11 EGC36728.1 - 0.77 10.5 4.3 0.51 11.1 1.9 1.9 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Ecm29 PF13001.7 EGC36729.1 - 6.5e-05 21.8 0.0 9.7e-05 21.2 0.0 1.3 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.22 EGC36729.1 - 0.0009 19.3 0.2 28 5.3 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat Cnd1 PF12717.7 EGC36729.1 - 0.0088 16.1 0.0 0.54 10.3 0.0 2.3 2 1 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.20 EGC36729.1 - 0.061 11.9 0.1 0.095 11.2 0.1 1.5 1 1 0 1 1 1 0 Adaptin N terminal region Vac14_Fab1_bd PF12755.7 EGC36729.1 - 0.072 13.7 0.0 0.53 10.9 0.0 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region ParcG PF10274.9 EGC36729.1 - 0.15 12.2 0.0 2.4 8.3 0.0 2.0 1 1 0 2 2 2 0 Parkin co-regulated protein adh_short PF00106.25 EGC36730.1 - 1.6e-28 99.5 0.0 8.2e-23 80.9 0.0 2.1 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36730.1 - 2.5e-12 46.9 0.0 1.4e-09 37.9 0.0 2.1 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36730.1 - 1.5e-09 38.0 0.0 5.9e-09 36.1 0.0 1.9 2 0 0 2 2 2 1 KR domain GDP_Man_Dehyd PF16363.5 EGC36730.1 - 0.0026 17.2 0.0 0.0056 16.1 0.0 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC36730.1 - 0.0094 15.4 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PLDc PF00614.22 EGC36730.1 - 0.18 12.0 1.6 0.25 11.6 0.1 2.0 2 0 0 2 2 2 0 Phospholipase D Active site motif Mnd1 PF03962.15 EGC36731.1 - 3.2e-22 78.6 0.1 3.2e-22 78.6 0.1 2.5 2 1 0 2 2 2 1 Mnd1 HTH domain LZ3wCH PF18517.1 EGC36731.1 - 1.1e-17 63.9 0.4 1.1e-17 63.9 0.4 3.4 4 0 0 4 4 4 1 Leucine zipper with capping helix domain UPF0242 PF06785.11 EGC36731.1 - 1.3e-05 25.4 8.6 2.3e-05 24.6 8.6 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Phage_GP20 PF06810.11 EGC36731.1 - 0.0018 18.1 11.9 0.0036 17.1 11.9 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 Atg14 PF10186.9 EGC36731.1 - 0.003 16.7 8.0 0.0051 16.0 8.0 1.3 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FapA PF03961.13 EGC36731.1 - 0.0046 15.6 8.1 0.0054 15.4 8.1 1.2 1 0 0 1 1 1 1 Flagellar Assembly Protein A S10_plectin PF03501.15 EGC36731.1 - 0.018 15.1 0.2 0.047 13.8 0.2 1.8 1 1 0 1 1 1 0 Plectin/S10 domain F_actin_bind PF08919.10 EGC36731.1 - 0.19 11.8 2.9 1.1 9.4 2.9 2.2 1 1 0 1 1 1 0 F-actin binding FAM76 PF16046.5 EGC36731.1 - 0.39 10.0 8.7 0.47 9.8 8.7 1.3 1 0 0 1 1 1 0 FAM76 protein ATG16 PF08614.11 EGC36731.1 - 0.81 9.9 11.9 0.65 10.2 9.3 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) DivIC PF04977.15 EGC36731.1 - 0.9 9.3 13.8 1.7 8.5 3.7 2.8 1 1 1 2 2 2 0 Septum formation initiator PCRF PF03462.18 EGC36731.1 - 1.8 8.4 12.8 0.64 9.9 9.9 1.7 1 1 1 2 2 2 0 PCRF domain HSCB_C PF07743.13 EGC36731.1 - 2.6 8.6 11.7 83 3.8 11.7 2.5 1 1 0 1 1 1 0 HSCB C-terminal oligomerisation domain LMBR1 PF04791.16 EGC36731.1 - 3.7 6.3 4.3 3.9 6.3 4.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Uteroglobin PF01099.17 EGC36731.1 - 5 7.5 8.5 1.1 9.7 1.4 2.5 1 1 1 2 2 2 0 Uteroglobin family Ank_2 PF12796.7 EGC36732.1 - 3.9e-10 40.2 2.0 0.00036 21.0 0.0 3.7 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36732.1 - 4.1e-06 27.2 1.1 0.025 15.2 0.1 3.8 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC36732.1 - 0.0011 19.3 3.4 0.27 11.9 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat Peptidase_M16 PF00675.20 EGC36732.1 - 0.0017 18.3 0.0 0.0047 16.9 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ank PF00023.30 EGC36732.1 - 0.0021 18.5 0.6 4.4 7.9 0.0 4.5 5 0 0 5 5 5 1 Ankyrin repeat Ank_5 PF13857.6 EGC36732.1 - 0.0045 17.3 1.1 0.8 10.1 0.1 4.2 3 1 1 4 4 4 1 Ankyrin repeats (many copies) DUF5082 PF16888.5 EGC36732.1 - 0.0066 16.7 0.8 0.037 14.3 0.8 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF5082) Pheromone PF08015.11 EGC36732.1 - 0.91 10.6 6.8 5.1 8.2 6.8 2.4 1 0 0 1 1 1 0 Fungal mating-type pheromone Ank_2 PF12796.7 EGC36733.1 - 1.3e-15 57.7 0.0 3.8e-08 33.8 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36733.1 - 1.5e-09 38.2 0.0 4.8e-07 30.2 0.0 2.9 2 1 1 3 3 3 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC36733.1 - 2.3e-08 34.1 0.0 0.05 13.9 0.0 3.3 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC36733.1 - 4.3e-08 32.8 0.0 0.012 16.0 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.30 EGC36733.1 - 0.00014 22.1 0.0 0.0051 17.2 0.1 2.6 2 0 0 2 2 2 1 Ankyrin repeat GATase_7 PF13537.6 EGC36733.1 - 0.08 12.9 0.0 2.4 8.1 0.0 2.4 2 1 0 2 2 2 0 Glutamine amidotransferase domain INSC_LBD PF16748.5 EGC36734.1 - 0.18 11.2 1.9 1.1 8.8 0.4 2.3 2 0 0 2 2 2 0 Inscuteable LGN-binding domain WD40 PF00400.32 EGC36735.1 - 0.00019 22.1 8.9 0.005 17.7 0.7 4.8 5 0 0 5 5 5 1 WD domain, G-beta repeat RAB3GAP2_N PF14655.6 EGC36735.1 - 0.00024 20.5 0.9 0.0014 18.0 0.3 2.2 1 1 1 2 2 2 2 Rab3 GTPase-activating protein regulatory subunit N-terminus BBS2_Mid PF14783.6 EGC36735.1 - 0.024 14.7 0.8 0.1 12.6 0.1 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Ribosomal_L18 PF17135.4 EGC36736.1 - 1.8e-80 268.8 4.7 2e-80 268.6 4.7 1.0 1 0 0 1 1 1 1 Ribosomal protein 60S L18 and 50S L18e Ribosomal_L27A PF00828.19 EGC36736.1 - 0.00018 22.2 0.3 0.0011 19.6 0.3 2.0 1 1 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A Metallophos PF00149.28 EGC36738.1 - 1.9e-15 57.9 3.2 4.2e-15 56.8 3.2 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DCP2 PF05026.13 EGC36740.1 - 6.2e-29 100.2 3.1 6.2e-29 100.2 3.1 1.9 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EGC36740.1 - 3e-13 49.9 0.0 5.7e-13 49.1 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain V_ATPase_I PF01496.19 EGC36740.1 - 0.00019 19.5 2.4 0.00034 18.7 2.4 1.3 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family Spt20 PF12090.8 EGC36740.1 - 0.00038 20.2 10.5 0.00038 20.2 10.5 3.2 2 1 1 3 3 3 1 Spt20 family TFIIA PF03153.13 EGC36740.1 - 0.007 16.4 13.1 0.007 16.4 13.1 2.2 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Neur_chan_memb PF02932.16 EGC36740.1 - 1.4 8.9 9.7 3.7 7.5 1.3 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Asn_synthase PF00733.21 EGC36742.1 - 2.4e-55 188.6 0.0 3e-55 188.3 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGC36742.1 - 7.4e-25 87.3 0.0 1.3e-24 86.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC36742.1 - 1.2e-15 57.9 0.0 1.9e-15 57.3 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC36742.1 - 0.05 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Aluminium induced protein tRNA_Me_trans PF03054.16 EGC36742.1 - 0.062 12.1 0.0 0.1 11.4 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase Methyltransf_7 PF03492.15 EGC36743.1 - 5.1e-43 147.6 5.7 6.5e-27 94.6 1.9 2.0 1 1 1 2 2 2 2 SAM dependent carboxyl methyltransferase Methyltransf_31 PF13847.6 EGC36743.1 - 0.0017 18.2 0.3 0.024 14.4 0.3 2.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36743.1 - 0.0082 16.8 0.0 0.044 14.4 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36743.1 - 0.013 16.3 0.1 0.087 13.6 0.0 2.5 2 1 0 2 2 2 0 Methyltransferase domain Ank_2 PF12796.7 EGC36744.1 - 1.4e-20 73.6 0.4 3.4e-12 46.8 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC36744.1 - 6.6e-20 71.2 1.4 1.6e-08 34.9 0.1 4.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC36744.1 - 8.9e-18 62.6 3.7 0.00022 21.4 0.2 5.3 5 0 0 5 5 5 4 Ankyrin repeat CN_hydrolase PF00795.22 EGC36744.1 - 1.2e-15 57.6 0.0 2e-15 56.9 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Ank PF00023.30 EGC36744.1 - 3.5e-13 49.3 3.9 7.2e-07 29.4 0.4 4.9 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGC36744.1 - 3.4e-12 46.4 3.6 9.2e-09 35.4 0.4 4.7 3 2 1 4 4 4 1 Ankyrin repeats (many copies) DUF5634 PF18681.1 EGC36744.1 - 0.092 13.1 2.7 0.15 12.5 0.3 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5634) Skp1_POZ PF03931.15 EGC36745.1 - 0.0004 20.5 0.9 0.0073 16.5 0.2 2.6 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Skp1 PF01466.19 EGC36745.1 - 0.00092 19.3 4.6 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain DDHD PF02862.17 EGC36745.1 - 0.0083 16.3 7.4 0.013 15.6 7.4 1.3 1 0 0 1 1 1 1 DDHD domain TMEM51 PF15345.6 EGC36745.1 - 0.17 11.7 6.0 0.33 10.8 6.0 1.4 1 0 0 1 1 1 0 Transmembrane protein 51 Menin PF05053.13 EGC36745.1 - 1.8 6.8 23.1 4 5.7 23.1 1.5 1 1 0 1 1 1 0 Menin Dapper PF15268.6 EGC36745.1 - 2 7.2 13.5 2.6 6.8 13.5 1.1 1 0 0 1 1 1 0 Dapper Peptidase_S49_N PF08496.10 EGC36745.1 - 5.1 7.2 11.2 0.4 10.7 5.7 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal HCO3_cotransp PF00955.21 EGC36745.1 - 9.8 4.9 7.1 13 4.5 7.1 1.3 1 0 0 1 1 1 0 HCO3- transporter family PDCD2_C PF04194.13 EGC36746.1 - 2.2e-29 102.7 0.9 2.2e-29 102.7 0.9 3.8 2 1 1 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain F-112 PF09645.10 EGC36746.1 - 0.41 10.8 5.9 0.75 9.9 0.6 2.5 2 0 0 2 2 2 0 F-112 protein Avl9 PF09794.9 EGC36748.1 - 1.2e-39 136.2 4.8 1.2e-39 136.2 4.8 1.9 2 0 0 2 2 2 1 Transport protein Avl9 Y_phosphatase3 PF13350.6 EGC36749.1 - 1.3e-45 156.1 0.0 1.6e-28 100.3 0.0 2.2 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGC36749.1 - 6.9e-05 22.5 0.2 0.001 18.7 0.0 2.5 3 0 0 3 3 3 1 Tyrosine phosphatase family GCV_T PF01571.21 EGC36751.1 - 0.0041 16.5 0.0 0.0079 15.6 0.0 1.5 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain SR-25 PF10500.9 EGC36753.1 - 0.0041 16.8 9.2 0.0099 15.5 9.2 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Chorion_2 PF03964.15 EGC36753.1 - 0.032 15.1 0.8 0.076 13.9 0.1 1.9 2 0 0 2 2 2 0 Chorion family 2 IMUP PF15761.5 EGC36753.1 - 0.13 13.0 10.1 0.42 11.3 10.1 1.8 1 0 0 1 1 1 0 Immortalisation up-regulated protein DUF3338 PF11819.8 EGC36753.1 - 1 9.4 5.7 2.9 7.9 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3338) FNIP PF05725.12 EGC36754.1 - 6.7e-119 387.9 119.7 3e-13 49.7 1.4 15.1 8 3 8 17 17 17 17 FNIP Repeat DUF1769 PF08588.10 EGC36754.1 - 0.0021 18.2 12.2 0.26 11.5 0.0 7.9 8 3 3 11 11 11 2 Protein of unknown function (DUF1769) BTG PF07742.12 EGC36755.1 - 4e-09 36.3 0.0 5.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 BTG family ECH_1 PF00378.20 EGC36756.1 - 2.9e-88 295.4 0.4 3.4e-88 295.2 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC36756.1 - 8.6e-42 143.8 1.6 1.1e-35 123.8 0.3 2.0 1 1 1 2 2 2 2 Enoyl-CoA hydratase/isomerase Peptidase_S49 PF01343.18 EGC36756.1 - 0.0033 17.4 0.0 0.046 13.7 0.0 2.6 3 0 0 3 3 3 1 Peptidase family S49 SDH_sah PF01972.16 EGC36756.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.5 2 0 0 2 2 2 0 Serine dehydrogenase proteinase SdrD_B PF17210.3 EGC36757.1 - 1.6e-15 57.3 3.0 6.3e-07 29.6 0.2 2.5 2 0 0 2 2 2 2 SdrD B-like domain CarboxypepD_reg PF13620.6 EGC36757.1 - 5e-08 33.1 1.3 0.0018 18.5 0.0 3.1 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGC36757.1 - 2.7e-06 27.6 1.3 0.013 15.8 0.1 2.7 2 0 0 2 2 2 2 Prealbumin-like fold domain DUF2012 PF09430.10 EGC36757.1 - 0.022 14.9 0.1 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) CarbopepD_reg_2 PF13715.6 EGC36757.1 - 0.063 13.3 0.1 1.3 9.0 0.0 2.7 2 0 0 2 2 2 0 CarboxypepD_reg-like domain MetallophosN PF16371.5 EGC36757.1 - 0.11 12.8 2.0 4.4 7.6 0.1 2.8 2 0 0 2 2 2 0 N terminal of Calcineurin-like phosphoesterase Pentaxin PF00354.17 EGC36757.1 - 0.13 12.0 1.3 0.19 11.4 0.1 1.8 2 0 0 2 2 2 0 Pentaxin family VPS9 PF02204.18 EGC36758.1 - 6.6e-29 100.2 1.0 1.4e-28 99.2 1.0 1.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DUF5601 PF18151.1 EGC36758.1 - 7.5e-12 45.4 0.0 6.7e-11 42.3 0.0 2.8 2 0 0 2 2 2 1 Domain of unknown function (DUF5601) eIF-5a PF01287.20 EGC36759.1 - 4.4e-23 81.2 0.0 6.2e-23 80.7 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold EFP_N PF08207.12 EGC36759.1 - 0.00017 21.5 0.1 0.00037 20.5 0.1 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Glyco_transf_20 PF00982.21 EGC36760.1 - 7.8e-149 496.4 0.0 1.2e-148 495.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.16 EGC36760.1 - 4.6e-62 209.2 0.0 7.4e-62 208.5 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.12 EGC36760.1 - 1.5e-05 24.9 0.0 0.015 15.0 0.0 2.7 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.11 EGC36760.1 - 0.24 11.1 0.6 0.58 9.8 0.2 1.7 2 0 0 2 2 2 0 Starch synthase catalytic domain PI3K_1B_p101 PF10486.9 EGC36761.1 - 0.013 13.3 7.4 0.017 13.0 7.4 1.1 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Rrn6 PF10214.9 EGC36761.1 - 0.086 11.3 4.3 0.11 11.0 4.3 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor Ribosomal_L6e PF01159.19 EGC36761.1 - 0.15 12.6 3.9 0.32 11.5 3.9 1.7 1 0 0 1 1 1 0 Ribosomal protein L6e DNA_pol_phi PF04931.13 EGC36761.1 - 0.17 10.0 13.7 0.33 9.0 13.7 1.5 1 0 0 1 1 1 0 DNA polymerase phi ORC_WH_C PF18137.1 EGC36761.1 - 7.5 6.6 9.4 9.4 6.3 7.3 2.1 2 0 0 2 2 2 0 Origin recognition complex winged helix C-terminal ADK PF00406.22 EGC36762.1 - 1.1e-08 35.3 2.6 2.9e-08 33.9 0.4 2.5 2 1 0 2 2 2 1 Adenylate kinase AAA_17 PF13207.6 EGC36762.1 - 5e-07 30.2 0.0 1.8e-06 28.4 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC36762.1 - 1.4e-05 25.6 0.2 7.6e-05 23.3 0.1 2.3 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGC36762.1 - 0.043 14.0 0.0 0.11 12.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC36762.1 - 0.092 12.0 2.0 0.15 11.3 0.0 2.3 3 0 0 3 3 3 0 Zeta toxin TsaE PF02367.17 EGC36762.1 - 0.11 12.6 0.0 0.26 11.3 0.0 1.6 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE NMT1_3 PF16868.5 EGC36762.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 NMT1-like family Arm PF00514.23 EGC36763.1 - 0.018 15.1 2.6 25 5.1 0.1 4.5 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat CelTOS PF18659.1 EGC36763.1 - 0.086 13.3 0.2 0.086 13.3 0.2 5.2 5 1 1 6 6 6 0 Cell-traversal protein for ookinetes and sporozoites YqfQ PF14181.6 EGC36763.1 - 0.28 11.4 2.7 1.1 9.4 2.7 2.0 1 0 0 1 1 1 0 YqfQ-like protein DUF760 PF05542.11 EGC36763.1 - 1.5 9.3 6.5 2.5 8.5 0.3 3.8 3 2 0 3 3 3 0 Protein of unknown function (DUF760) ATP-synt_E PF05680.12 EGC36763.1 - 3.4 8.1 6.4 9.9 6.6 6.4 1.9 1 0 0 1 1 1 0 ATP synthase E chain Ras PF00071.22 EGC36764.1 - 5e-32 110.8 0.8 5.4e-32 110.6 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC36764.1 - 5.4e-27 94.4 1.0 6e-27 94.2 1.0 1.0 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC36764.1 - 3e-09 36.6 0.6 3.4e-09 36.4 0.6 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC36764.1 - 2.9e-07 30.1 0.1 3.5e-07 29.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC36764.1 - 3.7e-07 30.2 0.0 4.5e-07 30.0 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC36764.1 - 5.8e-05 22.6 0.0 6.7e-05 22.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGC36764.1 - 0.0009 18.8 0.0 0.052 13.1 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain AAA_7 PF12775.7 EGC36764.1 - 0.0094 15.5 0.2 0.014 14.9 0.2 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region TK PF00265.18 EGC36764.1 - 0.012 15.4 0.0 0.014 15.3 0.0 1.0 1 0 0 1 1 1 0 Thymidine kinase Dynamin_N PF00350.23 EGC36764.1 - 0.03 14.4 0.2 0.54 10.3 0.1 2.1 1 1 0 2 2 2 0 Dynamin family PduV-EutP PF10662.9 EGC36764.1 - 0.046 13.5 0.1 0.073 12.8 0.1 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGC36764.1 - 0.058 12.9 0.0 1.1 8.8 0.0 2.0 1 1 1 2 2 2 0 Ferrous iron transport protein B AAA_16 PF13191.6 EGC36764.1 - 0.092 13.1 0.0 0.092 13.1 0.0 1.3 1 1 0 1 1 1 0 AAA ATPase domain DUF4555 PF15093.6 EGC36764.1 - 0.16 11.2 0.0 0.2 10.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4555) Memo PF01875.17 EGC36765.1 - 6.7e-68 228.8 0.5 1.9e-66 224.0 0.5 2.0 1 1 0 1 1 1 1 Memo-like protein zf-Tim10_DDP PF02953.15 EGC36766.1 - 8.2e-15 54.2 2.6 1e-14 53.9 2.6 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.13 EGC36766.1 - 0.03 14.0 0.8 0.039 13.7 0.8 1.2 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.9 EGC36766.1 - 0.33 11.0 3.9 1.5 8.8 0.2 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pribosyltran PF00156.27 EGC36767.1 - 2e-24 85.9 0.1 2.4e-24 85.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LRR_4 PF12799.7 EGC36768.1 - 1.5e-06 28.4 11.3 7.6e-05 23.0 1.8 5.5 3 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC36768.1 - 4.8e-06 26.2 3.3 4.8e-06 26.2 3.3 1.8 2 0 0 2 2 2 1 Leucine-rich repeat LRR_8 PF13855.6 EGC36768.1 - 5.6e-05 22.8 1.3 5.6e-05 22.8 1.3 2.6 3 0 0 3 3 3 1 Leucine rich repeat DUF2722 PF10846.8 EGC36770.1 - 0.0087 15.0 22.5 0.0087 15.0 22.5 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) PepSY_TM PF03929.16 EGC36770.1 - 0.26 10.9 5.4 0.46 10.1 5.4 1.4 1 0 0 1 1 1 0 PepSY-associated TM region DUF4770 PF15994.5 EGC36770.1 - 0.89 9.8 18.7 0.04 14.2 9.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4770) EOS1 PF12326.8 EGC36770.1 - 1.6 8.7 6.1 0.48 10.3 1.0 2.1 2 0 0 2 2 2 0 N-glycosylation protein OATP PF03137.20 EGC36770.1 - 4.4 5.5 4.0 7.7 4.7 4.0 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CCSAP PF15748.5 EGC36770.1 - 7.2 6.7 23.1 0.43 10.7 9.4 2.3 2 0 0 2 2 2 0 Centriole, cilia and spindle-associated Endostatin PF06482.11 EGC36770.1 - 9.8 5.5 17.8 1.3 8.5 10.8 2.0 2 0 0 2 2 2 0 Collagenase NC10 and Endostatin RBM39linker PF15519.6 EGC36770.1 - 9.8 7.3 16.2 90 4.3 11.9 3.3 2 1 0 2 2 2 0 linker between RRM2 and RRM3 domains in RBM39 protein FNIP PF05725.12 EGC36771.1 - 1.3e-108 355.0 76.4 9.5e-13 48.1 0.3 13.0 11 1 2 13 13 13 13 FNIP Repeat LRR_5 PF13306.6 EGC36771.1 - 0.0072 16.3 19.4 0.79 9.7 0.1 5.5 1 1 3 5 5 5 3 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC36771.1 - 0.02 15.1 1.1 29 5.0 0.0 4.7 5 0 0 5 5 5 0 Protein of unknown function (DUF1769) GHD PF17834.1 EGC36772.1 - 0.038 14.0 1.0 0.87 9.7 0.1 3.2 2 0 0 2 2 2 0 Beta-sandwich domain in beta galactosidase LRR_1 PF00560.33 EGC36773.1 - 0.0013 19.0 13.3 6.2 7.8 0.2 8.1 5 1 0 5 5 5 2 Leucine Rich Repeat LRR_6 PF13516.6 EGC36773.1 - 0.015 15.3 31.1 0.16 12.1 0.6 7.2 7 0 0 7 7 7 0 Leucine Rich repeat Interfer-bind PF09294.10 EGC36773.1 - 0.018 15.4 0.2 0.16 12.3 0.2 2.8 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III ATP-grasp_3 PF02655.14 EGC36773.1 - 0.067 13.2 2.7 1.2 9.2 0.0 3.3 3 0 0 3 3 3 0 ATP-grasp domain adh_short PF00106.25 EGC36774.1 - 7.1e-46 156.1 0.0 8.7e-46 155.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36774.1 - 5e-43 147.3 0.0 6.2e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36774.1 - 5.6e-05 23.1 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 KR domain F420_oxidored PF03807.17 EGC36774.1 - 0.0025 18.3 0.0 0.006 17.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DUF1776 PF08643.10 EGC36774.1 - 0.11 11.8 0.0 0.39 10.0 0.0 1.8 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Coatamer_beta_C PF07718.12 EGC36775.1 - 0.016 15.2 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 0 Coatomer beta C-terminal region HEAT PF02985.22 EGC36775.1 - 0.028 14.6 0.0 40 4.8 0.0 4.2 3 0 0 3 3 3 0 HEAT repeat DZR PF12773.7 EGC36776.1 - 0.00067 19.6 0.3 0.0011 19.0 0.3 1.4 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGC36776.1 - 0.011 15.5 4.8 0.019 14.7 4.8 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_15 PF17032.5 EGC36776.1 - 0.033 14.9 0.1 0.058 14.1 0.1 1.4 1 0 0 1 1 1 0 zinc-ribbon family zf-RanBP PF00641.18 EGC36776.1 - 0.037 13.4 5.3 0.071 12.4 5.3 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Epimerase PF01370.21 EGC36777.1 - 1.6e-22 80.1 0.0 2.9e-22 79.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC36777.1 - 2.7e-17 62.7 0.0 3.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.12 EGC36777.1 - 2.8e-13 49.6 0.0 1e-12 47.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein GDP_Man_Dehyd PF16363.5 EGC36777.1 - 2.6e-12 46.8 0.0 3.3e-12 46.4 0.0 1.4 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase NAD_binding_10 PF13460.6 EGC36777.1 - 8.8e-09 35.5 0.0 1.2e-08 35.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding NmrA PF05368.13 EGC36777.1 - 2.7e-08 33.7 0.0 4.8e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.15 EGC36777.1 - 2.4e-05 23.6 0.0 4.4e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.25 EGC36777.1 - 0.00064 19.2 0.0 0.0036 16.8 0.0 2.1 1 1 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.17 EGC36777.1 - 0.0027 16.9 0.2 0.016 14.4 0.2 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.10 EGC36777.1 - 0.0038 17.2 0.0 0.025 14.5 0.0 2.1 1 1 0 1 1 1 1 KR domain Ras PF00071.22 EGC36778.1 - 4e-64 215.1 0.3 4.7e-64 214.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC36778.1 - 3.5e-36 124.1 0.3 6.3e-36 123.2 0.3 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC36778.1 - 4.6e-19 68.5 0.1 5.7e-19 68.2 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family RsgA_GTPase PF03193.16 EGC36778.1 - 8.9e-07 29.0 0.2 0.02 14.8 0.1 2.3 2 1 0 2 2 2 2 RsgA GTPase Gtr1_RagA PF04670.12 EGC36778.1 - 9.1e-07 28.5 0.1 1.1e-06 28.2 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC36778.1 - 1.4e-05 24.7 0.2 4.8e-05 23.0 0.1 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC36778.1 - 1.7e-05 24.9 0.0 3.9e-05 23.7 0.0 1.6 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC36778.1 - 3.7e-05 23.2 0.0 7.6e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGC36778.1 - 0.0012 18.4 0.0 0.3 10.6 0.0 2.1 2 0 0 2 2 2 2 Ferrous iron transport protein B AAA PF00004.29 EGC36778.1 - 0.0017 18.7 0.0 1.2 9.6 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC36778.1 - 0.035 14.4 0.0 0.16 12.2 0.0 2.0 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC36778.1 - 0.038 13.7 0.0 0.11 12.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain LepB_N PF18640.1 EGC36778.1 - 0.039 13.6 0.1 0.05 13.2 0.1 1.2 1 0 0 1 1 1 0 LepB N-terminal domain AAA_16 PF13191.6 EGC36778.1 - 0.051 14.0 0.0 0.095 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGC36778.1 - 0.052 13.5 0.0 0.085 12.8 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGC36778.1 - 0.078 13.5 0.5 0.18 12.3 0.5 1.8 1 1 0 1 1 1 0 ABC transporter TniB PF05621.11 EGC36778.1 - 0.078 12.4 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein Coiled PF05710.12 EGC36779.1 - 0.0013 19.5 2.5 0.0013 19.5 2.5 1.1 1 0 0 1 1 1 1 Coiled coil XPG_N PF00752.17 EGC36780.1 - 2.4e-30 105.0 0.0 5.5e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGC36780.1 - 1.8e-26 92.3 0.0 4.3e-26 91.1 0.0 1.7 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.20 EGC36780.1 - 2e-06 28.3 0.0 6.5e-06 26.7 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DUF3231 PF11553.8 EGC36780.1 - 0.0023 17.6 0.1 0.2 11.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3231) 5_3_exonuc_N PF02739.16 EGC36780.1 - 0.0098 15.8 0.0 0.022 14.7 0.0 1.7 1 1 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain HHH_5 PF14520.6 EGC36780.1 - 0.02 15.5 0.0 0.057 14.0 0.0 1.8 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L10 PF00466.20 EGC36781.1 - 6e-22 77.7 0.1 8.6e-22 77.2 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 RL10P_insert PF17777.1 EGC36781.1 - 1e-19 70.3 0.0 3.8e-19 68.4 0.0 1.9 2 0 0 2 2 2 1 Insertion domain in 60S ribosomal protein L10P TcdB_N PF12918.7 EGC36781.1 - 0.033 14.5 1.5 0.071 13.4 0.6 2.0 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain F-actin_cap_A PF01267.17 EGC36781.1 - 0.049 13.1 0.1 0.083 12.3 0.1 1.3 1 0 0 1 1 1 0 F-actin capping protein alpha subunit Cullin_binding PF03556.15 EGC36781.1 - 0.094 13.2 0.1 0.18 12.3 0.1 1.5 1 0 0 1 1 1 0 Cullin binding Arf PF00025.21 EGC36782.1 - 1.6e-35 122.1 0.2 1.8e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGC36782.1 - 1.1e-06 28.2 0.0 1.5e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Roc PF08477.13 EGC36782.1 - 0.00083 19.6 0.0 0.0012 19.0 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NOG1 PF06858.14 EGC36782.1 - 0.00096 18.9 0.1 0.0019 17.9 0.1 1.5 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Ras PF00071.22 EGC36782.1 - 0.0011 18.5 0.0 0.0014 18.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGC36782.1 - 0.013 14.9 0.1 0.015 14.7 0.1 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGC36782.1 - 0.024 13.8 3.2 0.05 12.8 1.8 2.1 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.23 EGC36782.1 - 0.037 14.1 0.4 0.11 12.5 0.2 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase zinc_ribbon_13 PF09855.9 EGC36782.1 - 0.057 13.6 0.1 0.12 12.5 0.1 1.5 1 0 0 1 1 1 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) Pkinase PF00069.25 EGC36783.1 - 1.4e-68 231.1 0.0 2.3e-68 230.4 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36783.1 - 2.7e-47 161.2 0.0 4.5e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGC36783.1 - 3.2e-17 62.6 0.0 7.7e-17 61.4 0.0 1.7 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGC36783.1 - 9.5e-06 24.6 0.0 1.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC36783.1 - 0.0002 20.8 0.3 0.00059 19.2 0.0 1.9 2 1 0 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGC36783.1 - 0.0028 16.6 0.4 0.042 12.8 0.4 2.0 1 1 0 1 1 1 1 Haspin like kinase domain KIND PF16474.5 EGC36783.1 - 0.0071 16.3 0.1 0.017 15.0 0.0 1.6 2 0 0 2 2 2 1 Kinase non-catalytic C-lobe domain Seadorna_VP7 PF07387.11 EGC36783.1 - 0.0097 15.0 0.0 0.018 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 G5 PF07501.12 EGC36783.1 - 0.19 12.2 0.4 0.46 10.9 0.4 1.6 1 0 0 1 1 1 0 G5 domain TFIIA PF03153.13 EGC36784.1 - 4.3 7.2 21.7 5 7.0 21.7 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Homeodomain PF00046.29 EGC36785.1 - 1.9e-05 24.4 1.3 3.7e-05 23.5 1.3 1.5 1 0 0 1 1 1 1 Homeodomain YL1 PF05764.13 EGC36785.1 - 0.016 15.4 5.9 0.019 15.1 5.9 1.1 1 0 0 1 1 1 0 YL1 nuclear protein Sigma70_ner PF04546.13 EGC36785.1 - 0.017 15.0 1.7 0.023 14.6 1.7 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Spt5_N PF11942.8 EGC36785.1 - 0.47 11.5 12.7 0.27 12.2 11.1 1.5 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.14 EGC36785.1 - 0.72 8.1 7.4 0.88 7.8 7.4 1.0 1 0 0 1 1 1 0 CDC45-like protein PBP1_TM PF14812.6 EGC36785.1 - 8.9 6.8 16.5 25 5.4 16.5 1.8 1 1 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGAP PF00616.19 EGC36786.1 - 1.1e-62 211.4 0.3 1.1e-62 211.4 0.3 2.7 2 0 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.15 EGC36786.1 - 4.9e-28 98.0 11.4 1.4e-27 96.5 11.4 1.8 1 0 0 1 1 1 1 RasGAP C-terminus SKA1 PF07160.12 EGC36786.1 - 0.0049 16.7 4.9 0.0049 16.7 4.9 2.4 2 0 0 2 2 2 1 Spindle and kinetochore-associated protein 1 YabA PF06156.13 EGC36786.1 - 7.9 7.2 19.5 0.11 13.2 3.8 3.9 5 0 0 5 5 5 0 Initiation control protein YabA adh_short PF00106.25 EGC36788.1 - 1.6e-46 158.2 0.1 2.1e-46 157.8 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36788.1 - 1.8e-32 112.8 0.0 2.2e-32 112.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36788.1 - 1.3e-10 41.5 0.0 1.9e-10 40.9 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGC36788.1 - 1.7e-07 31.4 0.0 2.1e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding DUF1776 PF08643.10 EGC36788.1 - 2.4e-06 27.1 0.0 4e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGC36788.1 - 9.3e-06 25.3 0.1 5e-05 22.9 0.1 2.2 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGC36788.1 - 0.0018 17.5 0.1 0.003 16.7 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGC36788.1 - 0.14 11.5 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase adh_short PF00106.25 EGC36789.1 - 3.1e-48 163.8 0.1 4.8e-48 163.2 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36789.1 - 7.4e-33 114.1 0.0 9.5e-33 113.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36789.1 - 3.7e-09 36.7 0.0 5.5e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC36789.1 - 1.1e-07 31.6 0.2 4.4e-07 29.6 0.2 1.8 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGC36789.1 - 6.7e-06 26.1 0.0 9.4e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC36789.1 - 3.6e-05 23.4 0.1 5.7e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family MMS19_N PF14500.6 EGC36789.1 - 0.042 13.4 0.0 0.078 12.5 0.0 1.5 1 0 0 1 1 1 0 Dos2-interacting transcription regulator of RNA-Pol-II Polysacc_synt_2 PF02719.15 EGC36789.1 - 0.065 12.4 0.3 0.1 11.7 0.3 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGC36789.1 - 0.11 11.5 0.0 0.2 10.7 0.0 1.3 1 0 0 1 1 1 0 RmlD substrate binding domain ANAPC4_WD40 PF12894.7 EGC36790.1 - 2.5e-05 24.5 0.1 0.084 13.2 0.0 4.8 5 0 0 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC36790.1 - 0.00047 20.9 4.7 19 6.4 0.0 6.6 6 0 0 6 6 6 1 WD domain, G-beta repeat SUFU_C PF12470.8 EGC36790.1 - 0.048 13.7 0.1 0.048 13.7 0.1 2.6 2 0 0 2 2 2 0 Suppressor of Fused Gli/Ci N terminal binding domain BPL_LplA_LipB PF03099.19 EGC36791.1 - 1.3e-18 67.2 0.0 2.1e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.17 EGC36791.1 - 2.1e-09 37.1 0.3 5.3e-09 35.8 0.1 1.8 2 0 0 2 2 2 1 Biotin protein ligase C terminal domain DUF4416 PF14385.6 EGC36791.1 - 0.018 14.9 0.2 0.058 13.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) BPL_LplA_LipB_2 PF16917.5 EGC36791.1 - 0.077 12.5 0.0 0.19 11.2 0.0 1.7 1 1 0 1 1 1 0 Biotin/lipoate A/B protein ligase family SAM_PNT PF02198.16 EGC36792.1 - 2e-08 34.1 0.2 7.3e-08 32.3 0.2 2.0 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Trypsin_2 PF13365.6 EGC36792.1 - 7.4e-06 26.9 0.0 0.00012 23.0 0.0 2.3 1 1 0 1 1 1 1 Trypsin-like peptidase domain SR-25 PF10500.9 EGC36792.1 - 0.58 9.7 9.7 0.97 9.0 9.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Zip PF02535.22 EGC36792.1 - 0.8 8.9 5.3 1.2 8.3 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter ECH_1 PF00378.20 EGC36793.1 - 5.8e-14 52.0 0.0 2e-13 50.3 0.0 1.7 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase ECH_2 PF16113.5 EGC36793.1 - 0.038 13.5 0.1 0.2 11.1 0.1 2.0 1 1 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF3741 PF12552.8 EGC36793.1 - 0.2 11.6 1.5 0.56 10.2 1.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) Carboxyl_trans PF01039.22 EGC36793.1 - 0.2 10.2 0.0 0.28 9.8 0.0 1.1 1 0 0 1 1 1 0 Carboxyl transferase domain PDEase_II PF02112.15 EGC36794.1 - 6.4e-98 328.0 1.0 8.2e-98 327.6 1.0 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II EGF_2 PF07974.13 EGC36795.1 - 6.6e-08 32.8 30.0 6.5e-06 26.4 13.3 2.8 2 0 0 2 2 2 2 EGF-like domain TIG PF01833.24 EGC36795.1 - 0.0012 18.8 2.0 0.0012 18.8 2.0 4.4 5 0 0 5 5 5 1 IPT/TIG domain Laminin_EGF PF00053.24 EGC36795.1 - 0.0032 17.6 22.5 0.22 11.7 4.0 3.0 2 0 0 2 2 2 2 Laminin EGF domain Vps36-NZF-N PF16988.5 EGC36795.1 - 0.011 15.1 5.7 1.3 8.5 0.5 2.8 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain EGF PF00008.27 EGC36795.1 - 0.083 13.2 20.2 0.074 13.4 7.3 3.0 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 EGC36795.1 - 4.9 7.3 17.0 0.87 9.7 7.3 2.6 2 0 0 2 2 2 0 Tenascin EGF domain hEGF PF12661.7 EGC36795.1 - 7.1 7.4 10.7 1.4 9.7 5.8 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF FMO-like PF00743.19 EGC36796.1 - 4.1e-61 207.0 3.3 5e-61 206.7 3.3 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.6 EGC36796.1 - 8.5e-22 77.8 0.4 2.7e-15 56.4 0.0 2.8 2 1 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGC36796.1 - 2.5e-13 50.0 0.0 5.4e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.6 EGC36796.1 - 4.8e-10 39.1 1.1 6.8e-08 32.0 0.4 3.1 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.24 EGC36796.1 - 1.3e-05 24.9 0.0 0.38 10.3 0.0 3.1 2 1 0 3 3 3 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC36796.1 - 1.7e-05 25.0 0.0 3.8e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGC36796.1 - 7.9e-05 21.5 0.1 0.0039 15.9 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.27 EGC36796.1 - 0.0002 21.8 0.0 0.3 11.7 0.0 2.8 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.6 EGC36796.1 - 0.00087 19.3 0.0 0.079 13.0 0.0 2.6 2 0 0 2 2 2 1 FAD-NAD(P)-binding FAD_binding_2 PF00890.24 EGC36796.1 - 0.0083 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.7 EGC36796.1 - 0.066 12.6 0.0 0.16 11.3 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF5502 PF17606.2 EGC36796.1 - 0.42 11.3 2.9 1.5 9.6 0.4 2.9 3 0 0 3 3 3 0 Family of unknown function (DUF5502) HIT PF01230.23 EGC36798.1 - 7.3e-22 77.9 0.1 9e-22 77.7 0.1 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.8 EGC36798.1 - 5.4e-14 52.6 0.0 6.7e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding DUF4931 PF16285.5 EGC36798.1 - 0.11 11.8 0.2 0.16 11.3 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4931) WI12 PF07107.11 EGC36798.1 - 0.16 12.1 0.0 0.26 11.5 0.0 1.3 1 0 0 1 1 1 0 Wound-induced protein WI12 NAD_binding_4 PF07993.12 EGC36799.1 - 5.4e-61 206.0 0.0 8.9e-61 205.3 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.21 EGC36799.1 - 3.4e-23 81.7 0.0 7.9e-23 80.6 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.19 EGC36799.1 - 4.9e-19 68.4 0.1 1.5e-18 66.8 0.1 1.9 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.21 EGC36799.1 - 5e-07 29.4 0.0 3.7e-06 26.6 0.0 2.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC36799.1 - 3.7e-05 22.9 0.6 0.0063 15.6 0.7 3.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC36799.1 - 0.062 12.7 0.8 1.2 8.5 0.8 2.3 1 1 0 1 1 1 0 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC36799.1 - 0.068 12.3 0.0 0.19 10.8 0.0 1.8 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.25 EGC36800.1 - 2.1e-50 170.9 0.0 3.1e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC36800.1 - 2.2e-33 115.8 0.0 3e-33 115.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC36800.1 - 3.8e-07 30.2 0.0 5.9e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC36800.1 - 2e-05 24.2 0.0 4.1e-05 23.1 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.13 EGC36800.1 - 0.00023 20.8 0.0 0.00038 20.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC36800.1 - 0.0014 18.6 0.0 0.002 18.1 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC36800.1 - 0.02 14.3 0.0 0.034 13.6 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Herpes_U30 PF04523.13 EGC36800.1 - 0.068 11.1 0.0 0.086 10.7 0.0 1.0 1 0 0 1 1 1 0 Herpes virus tegument protein U30 RmlD_sub_bind PF04321.17 EGC36800.1 - 0.076 12.1 0.0 0.096 11.8 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain zf-LITAF-like PF10601.9 EGC36801.1 - 3.4e-21 75.3 11.1 3.6e-21 75.2 11.1 1.0 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain zf-DNL PF05180.12 EGC36801.1 - 0.19 11.7 4.3 0.93 9.5 0.3 2.3 2 0 0 2 2 2 0 DNL zinc finger Thoc2 PF11732.8 EGC36802.1 - 0.03 14.4 0.2 0.1 12.7 0.2 1.9 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Myosin_head PF00063.21 EGC36803.1 - 1.1e-273 909.6 0.3 1.4e-273 909.2 0.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC36803.1 - 6.9e-44 149.8 7.8 1.2e-43 149.0 7.8 1.4 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGC36803.1 - 2.5e-16 59.0 0.2 1.8e-15 56.2 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.6 EGC36803.1 - 2.9e-15 55.8 0.1 8.5e-15 54.4 0.1 1.9 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC36803.1 - 1e-09 37.9 0.0 2.9e-09 36.5 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain ABC_tran PF00005.27 EGC36803.1 - 0.0068 16.9 0.0 0.027 15.0 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_16 PF13191.6 EGC36803.1 - 0.017 15.5 0.0 0.038 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.12 EGC36803.1 - 0.083 12.2 0.0 0.23 10.7 0.0 1.7 1 0 0 1 1 1 0 Zeta toxin RsgA_GTPase PF03193.16 EGC36803.1 - 0.13 12.2 0.0 0.25 11.2 0.0 1.4 1 0 0 1 1 1 0 RsgA GTPase AAA_22 PF13401.6 EGC36803.1 - 0.13 12.5 0.0 0.48 10.7 0.0 1.9 1 0 0 1 1 1 0 AAA domain TFIIA PF03153.13 EGC36803.1 - 7.4 6.4 14.4 18 5.1 14.4 1.6 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PDEase_I PF00233.19 EGC36805.1 - 5.2e-82 275.2 2.0 5.2e-82 275.2 2.0 2.9 3 1 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.12 EGC36805.1 - 1.4e-06 28.1 0.1 1.4e-06 28.1 0.1 2.7 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal PARP PF00644.20 EGC36806.1 - 3.1e-21 75.9 0.0 1.2e-20 74.0 0.0 1.9 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC36806.1 - 8.3e-18 64.8 0.3 8.3e-18 64.8 0.3 2.2 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT_2 PF16589.5 EGC36806.1 - 9.5e-11 42.0 1.3 4.1e-10 39.9 1.3 2.2 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain WGR PF05406.15 EGC36806.1 - 8e-08 32.2 0.5 1.9e-07 31.0 0.5 1.6 1 0 0 1 1 1 1 WGR domain Ank_2 PF12796.7 EGC36806.1 - 1.6e-06 28.6 0.0 0.00035 21.1 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BRCT PF00533.26 EGC36806.1 - 2.4e-06 27.8 0.7 2.4e-06 27.8 0.7 3.5 4 0 0 4 4 4 1 BRCA1 C Terminus (BRCT) domain Ank_5 PF13857.6 EGC36806.1 - 2.5e-06 27.6 0.5 0.00043 20.5 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC36806.1 - 7.6e-06 26.4 0.1 0.00073 20.0 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeats (many copies) PTCB-BRCT PF12738.7 EGC36806.1 - 0.00039 20.3 0.1 0.0031 17.4 0.0 2.6 2 0 0 2 2 2 1 twin BRCT domain Ank_3 PF13606.6 EGC36806.1 - 0.0023 18.3 0.3 0.98 10.2 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat Pkinase_Tyr PF07714.17 EGC36807.1 - 1.4e-40 139.2 0.0 1.6e-40 139.0 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC36807.1 - 2.4e-38 132.0 0.0 2.7e-38 131.8 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC36807.1 - 0.00055 18.8 0.0 0.00097 18.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Kdo PF06293.14 EGC36807.1 - 0.13 11.6 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Alba PF01918.21 EGC36808.1 - 1.2e-10 41.0 0.0 2.7e-10 39.9 0.0 1.6 1 0 0 1 1 1 1 Alba Rpp20 PF12328.8 EGC36808.1 - 1.1e-05 25.5 7.9 0.00026 20.9 0.0 3.5 2 1 1 3 3 3 2 Rpp20 subunit of nuclear RNase MRP and P BCS1_N PF08740.11 EGC36809.1 - 1.7e-33 116.2 0.0 2.7e-33 115.5 0.0 1.3 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.29 EGC36809.1 - 7.6e-22 78.1 0.1 1.7e-20 73.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.13 EGC36809.1 - 4.3e-06 26.1 0.1 1.9e-05 24.0 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGC36809.1 - 0.00056 20.3 0.0 0.0045 17.4 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain ABC_tran PF00005.27 EGC36809.1 - 0.0014 19.2 0.5 0.0072 16.8 0.2 2.3 2 1 0 2 2 2 1 ABC transporter AAA_29 PF13555.6 EGC36809.1 - 0.0018 18.0 0.0 0.0043 16.8 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain RuvB_N PF05496.12 EGC36809.1 - 0.0033 17.2 0.0 0.0064 16.2 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain MMR_HSR1 PF01926.23 EGC36809.1 - 0.0075 16.3 0.1 0.032 14.3 0.0 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC36809.1 - 0.01 15.7 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 0 RsgA GTPase DDRGK PF09756.9 EGC36809.1 - 0.014 15.0 0.2 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 DDRGK domain AAA_5 PF07728.14 EGC36809.1 - 0.016 15.2 0.0 0.046 13.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) RNA_helicase PF00910.22 EGC36809.1 - 0.046 14.1 0.0 0.15 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase ATPase PF06745.13 EGC36809.1 - 0.14 11.5 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.6 EGC36809.1 - 0.17 12.4 3.1 0.16 12.4 0.6 2.1 2 1 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.19 EGC36810.1 - 1.3e-19 70.7 0.0 5.9e-19 68.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGC36810.1 - 2.5e-05 23.7 1.8 0.00015 21.2 0.4 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.6 EGC36810.1 - 2.7e-05 23.6 0.1 0.00053 19.3 0.1 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.24 EGC36810.1 - 5.5e-05 22.9 0.2 0.00075 19.2 0.2 2.1 2 0 0 2 2 2 1 FAD dependent oxidoreductase Shikimate_DH PF01488.20 EGC36810.1 - 0.00011 22.3 0.1 0.00024 21.2 0.1 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase Rot1 PF10681.9 EGC36810.1 - 0.00026 20.6 0.0 0.03 13.8 0.0 2.2 2 0 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal Thi4 PF01946.17 EGC36810.1 - 0.003 16.8 0.2 0.0063 15.8 0.1 1.6 2 0 0 2 2 2 1 Thi4 family TrkA_N PF02254.18 EGC36810.1 - 0.0037 17.5 0.1 0.04 14.2 0.1 2.2 2 0 0 2 2 2 1 TrkA-N domain Pyr_redox PF00070.27 EGC36810.1 - 0.0058 17.2 0.4 0.14 12.8 0.1 2.6 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.6 EGC36810.1 - 0.0058 17.1 0.0 0.045 14.2 0.0 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Lycopene_cycl PF05834.12 EGC36810.1 - 0.01 14.9 0.1 0.44 9.5 0.1 2.7 3 0 0 3 3 3 0 Lycopene cyclase protein NAD_binding_8 PF13450.6 EGC36810.1 - 0.016 15.5 0.0 0.031 14.5 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain SE PF08491.10 EGC36810.1 - 0.027 13.5 0.0 0.081 12.0 0.0 1.7 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.14 EGC36810.1 - 0.064 11.9 0.2 0.6 8.7 0.1 2.2 2 0 0 2 2 2 0 HI0933-like protein ThiF PF00899.21 EGC36810.1 - 0.073 12.4 0.4 0.47 9.8 0.2 2.0 2 0 0 2 2 2 0 ThiF family FAD_binding_2 PF00890.24 EGC36810.1 - 0.078 12.0 0.1 0.14 11.2 0.1 1.4 1 0 0 1 1 1 0 FAD binding domain UFC1 PF08694.11 EGC36812.1 - 2e-85 284.1 1.1 2.2e-85 284.0 1.1 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.22 EGC36812.1 - 0.0035 17.6 0.0 0.0042 17.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UQ_con PF00179.26 EGC36812.1 - 0.0097 15.6 1.0 0.017 14.8 1.0 1.5 1 1 0 1 1 1 1 Ubiquitin-conjugating enzyme Spc42p PF11544.8 EGC36812.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.4 1 0 0 1 1 1 0 Spindle pole body component Spc42p BRCT_2 PF16589.5 EGC36813.1 - 7.2e-11 42.3 0.1 9e-11 42.0 0.1 1.1 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC36813.1 - 1.7e-07 31.5 0.0 2.5e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGC36813.1 - 0.0046 16.9 0.0 0.0066 16.4 0.0 1.4 1 1 0 1 1 1 1 twin BRCT domain DUF3850 PF12961.7 EGC36813.1 - 0.02 14.9 0.3 0.042 13.9 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3850) FNIP PF05725.12 EGC36814.1 - 7.1e-102 333.4 62.8 3e-18 65.7 0.6 10.4 5 2 7 12 12 12 12 FNIP Repeat Pescadillo_N PF06732.11 EGC36815.1 - 1.6e-107 359.1 14.6 1.6e-107 359.1 14.6 2.3 2 0 0 2 2 2 1 Pescadillo N-terminus BRCT_2 PF16589.5 EGC36815.1 - 1.6e-10 41.2 0.1 5.3e-10 39.6 0.1 2.0 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC36815.1 - 0.0017 18.7 0.6 0.0073 16.7 0.1 2.5 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Yippee-Mis18 PF03226.14 EGC36816.1 - 4.7e-22 78.2 0.5 4.7e-22 78.2 0.5 2.0 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DUF5113 PF17140.4 EGC36816.1 - 0.049 13.4 3.9 0.52 10.1 0.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF5113) MAT1 PF06391.13 EGC36817.1 - 5.1e-31 108.1 32.4 8.5e-31 107.4 32.0 1.6 1 1 0 1 1 1 1 CDK-activating kinase assembly factor MAT1 SET PF00856.28 EGC36818.1 - 1.5e-17 64.5 1.0 1.5e-17 64.5 1.0 5.5 3 3 0 3 3 3 1 SET domain A_deaminase PF00962.22 EGC36820.1 - 9e-116 386.8 0.3 1.2e-115 386.4 0.3 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase TIR_3 PF18567.1 EGC36821.1 - 0.022 14.7 0.0 0.032 14.2 0.0 1.2 1 0 0 1 1 1 0 Toll/interleukin-1 receptor domain CMAS PF02353.20 EGC36822.1 - 7.5e-76 255.0 1.0 9.5e-76 254.7 1.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGC36822.1 - 1.9e-12 47.3 0.0 2.7e-12 46.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC36822.1 - 2.5e-11 44.1 0.0 6.5e-11 42.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC36822.1 - 1.9e-08 34.9 0.0 4.8e-08 33.5 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC36822.1 - 1.1e-06 28.5 0.1 2e-06 27.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC36822.1 - 1.6e-06 28.8 0.0 4.1e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.13 EGC36822.1 - 0.00078 19.0 0.0 0.0022 17.6 0.0 1.7 1 0 0 1 1 1 1 Histone methylation protein DOT1 MTS PF05175.14 EGC36822.1 - 0.0038 16.8 0.0 0.0065 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain E1_UFD PF09358.10 EGC36822.1 - 0.006 17.3 0.1 0.17 12.6 0.0 2.7 2 0 0 2 2 2 1 Ubiquitin fold domain ADH_zinc_N PF00107.26 EGC36822.1 - 0.0099 15.9 0.0 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 EGC36822.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 Putative methyltransferase UPF0020 PF01170.18 EGC36822.1 - 0.066 12.9 0.0 0.16 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 MetW PF07021.12 EGC36822.1 - 0.07 12.7 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW FAD_binding_3 PF01494.19 EGC36823.1 - 6.4e-24 84.9 0.0 1.4e-23 83.7 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain Pyr_redox_2 PF07992.14 EGC36823.1 - 3.3e-06 26.6 1.0 0.00063 19.1 0.0 2.6 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.12 EGC36823.1 - 1.1e-05 24.7 0.3 0.00032 19.9 0.1 2.5 2 1 0 2 2 2 1 Lycopene cyclase protein Trp_halogenase PF04820.14 EGC36823.1 - 1.4e-05 24.1 0.1 0.014 14.2 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase Pyr_redox_3 PF13738.6 EGC36823.1 - 1.8e-05 24.1 0.0 5.5e-05 22.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC36823.1 - 0.00023 20.5 0.1 0.00033 20.0 0.1 1.4 1 0 0 1 1 1 1 Thi4 family DAO PF01266.24 EGC36823.1 - 0.00035 20.3 0.0 0.00092 18.9 0.0 1.6 2 0 0 2 2 2 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.6 EGC36823.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.18 EGC36823.1 - 0.0093 16.2 0.1 0.022 15.0 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.20 EGC36823.1 - 0.011 15.8 0.1 0.025 14.6 0.1 1.8 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.14 EGC36823.1 - 0.055 12.2 0.3 0.12 11.0 0.1 1.6 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.10 EGC36823.1 - 0.084 11.9 0.0 0.35 9.9 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_7 PF13241.6 EGC36823.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.8 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EGC36823.1 - 0.13 12.8 0.1 0.54 10.8 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.24 EGC36823.1 - 0.14 11.2 0.0 0.22 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain NAD_binding_9 PF13454.6 EGC36823.1 - 0.23 11.4 0.2 2 8.4 0.0 2.2 2 0 0 2 2 2 0 FAD-NAD(P)-binding BHD_3 PF10405.9 EGC36824.1 - 2e-23 82.6 0.0 4.2e-23 81.5 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.15 EGC36824.1 - 3e-18 65.9 3.8 3e-18 65.9 3.8 4.1 3 1 1 5 5 5 1 Rad4 transglutaminase-like domain BHD_1 PF10403.9 EGC36824.1 - 1.5e-09 37.6 0.8 4.9e-09 35.9 0.3 2.3 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.9 EGC36824.1 - 1.6e-05 25.8 1.8 1.6e-05 25.8 1.8 5.8 4 2 0 4 4 4 1 Rad4 beta-hairpin domain 2 Secretin_N_2 PF07655.13 EGC36825.1 - 0.15 12.6 42.2 1.4 9.5 14.6 3.5 3 0 0 3 3 3 0 Secretin N-terminal domain Patatin PF01734.22 EGC36825.1 - 0.62 10.2 3.8 2.1 8.4 3.8 1.9 1 0 0 1 1 1 0 Patatin-like phospholipase SNF2_N PF00176.23 EGC36826.1 - 1.6e-68 231.0 0.9 1.6e-68 231.0 0.9 1.7 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.6 EGC36826.1 - 1.7e-45 154.7 23.4 1.7e-45 154.7 23.4 4.1 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.31 EGC36826.1 - 4.7e-19 68.8 0.1 6.3e-17 61.9 0.0 3.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36826.1 - 9.3e-10 38.8 0.0 9.3e-10 38.8 0.0 4.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DEAD PF00270.29 EGC36826.1 - 7.9e-05 22.5 0.0 0.00034 20.4 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase RBR PF17208.3 EGC36826.1 - 0.006 17.3 15.1 0.0078 16.9 11.2 3.4 2 0 0 2 2 2 1 RNA binding Region AAA_18 PF13238.6 EGC36826.1 - 0.048 14.2 0.0 0.048 14.2 0.0 4.2 3 1 0 3 3 3 0 AAA domain DBI_PRT PF02277.17 EGC36826.1 - 0.15 11.3 0.0 0.23 10.7 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyltransferase WWE PF02825.20 EGC36827.1 - 1.7e-13 50.9 4.1 1.7e-13 50.9 4.1 2.2 2 0 0 2 2 2 1 WWE domain EF-hand_1 PF00036.32 EGC36827.1 - 0.00044 19.6 3.3 0.00074 18.9 0.7 2.5 2 0 0 2 2 2 1 EF hand EF-hand_7 PF13499.6 EGC36827.1 - 0.0018 18.6 0.8 0.0056 17.1 0.8 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.6 EGC36827.1 - 0.084 12.7 2.0 0.25 11.2 0.8 2.4 2 1 0 2 2 2 0 EF-hand domain pair EF-hand_5 PF13202.6 EGC36827.1 - 0.091 12.3 0.3 0.26 10.8 0.3 1.8 1 0 0 1 1 1 0 EF hand AdHead_fibreRBD PF16812.5 EGC36827.1 - 0.094 12.5 0.6 0.2 11.5 0.6 1.5 1 0 0 1 1 1 0 C-terminal head domain of the fowl adenovirus type 1 long fibre Urm1 PF09138.11 EGC36827.1 - 0.11 12.8 1.6 1.1 9.7 0.5 2.8 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) EF-hand_6 PF13405.6 EGC36827.1 - 0.12 12.4 0.6 1.8 8.7 0.2 2.7 2 0 0 2 2 2 0 EF-hand domain Membralin PF09746.9 EGC36827.1 - 8.9 5.2 10.3 14 4.6 10.3 1.3 1 0 0 1 1 1 0 Tumour-associated protein Mur_ligase_M PF08245.12 EGC36829.1 - 7.4e-07 29.4 0.0 3.7e-05 23.8 0.0 2.8 2 1 0 2 2 2 1 Mur ligase middle domain CBM49 PF09478.10 EGC36830.1 - 6.8e-15 55.1 3.0 9.4e-15 54.7 3.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TILa PF12714.7 EGC36830.1 - 1.5 8.8 8.3 6.7 6.8 2.1 2.3 1 1 1 2 2 2 0 TILa domain BTB PF00651.31 EGC36831.1 - 6.2e-22 77.9 7.3 1.7e-21 76.5 1.4 3.0 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.15 EGC36831.1 - 0.00011 22.2 1.3 0.0026 17.8 0.1 2.7 2 1 1 3 3 3 1 BTB And C-terminal Kelch Rad60-SLD PF11976.8 EGC36831.1 - 0.083 12.7 1.9 0.12 12.2 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like Dymeclin PF09742.9 EGC36832.1 - 5.6e-89 299.3 45.6 5.6e-89 299.3 45.6 1.4 2 0 0 2 2 2 1 Dyggve-Melchior-Clausen syndrome protein Androgen_recep PF02166.16 EGC36832.1 - 1.1 8.1 11.9 1.7 7.4 11.9 1.2 1 0 0 1 1 1 0 Androgen receptor MPM1 PF17234.2 EGC36832.1 - 6.9 6.9 19.2 0.14 12.4 8.5 2.7 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 OAD_gamma PF04277.13 EGC36833.1 - 1.8 9.2 5.8 6 7.5 5.8 1.9 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Peptidase_M3 PF01432.20 EGC36834.1 - 7.1e-126 421.1 3.1 7.1e-126 421.1 3.1 2.0 2 0 0 2 2 2 2 Peptidase family M3 EphA2_TM PF14575.6 EGC36835.1 - 0.018 15.9 0.3 0.047 14.6 0.2 1.8 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMEM51 PF15345.6 EGC36835.1 - 0.028 14.3 0.2 0.054 13.3 0.1 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 DUF5385 PF17359.2 EGC36835.1 - 0.052 13.1 0.1 0.087 12.4 0.1 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5385) MerC PF03203.14 EGC36835.1 - 0.089 13.3 11.0 0.12 12.9 10.7 1.4 1 1 0 1 1 1 0 MerC mercury resistance protein DUF202 PF02656.15 EGC36835.1 - 0.37 11.3 8.3 0.8 10.2 2.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF202) DUF1980 PF09323.10 EGC36835.1 - 8.1 6.3 17.0 8.7e+02 -0.3 17.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) TMEM154 PF15102.6 EGC36835.1 - 9.9 6.1 6.1 98 2.8 5.8 2.3 1 1 1 2 2 2 0 TMEM154 protein family RasGEF PF00617.19 EGC36836.1 - 2.5e-50 171.1 5.1 4.4e-50 170.3 1.3 2.8 2 0 0 2 2 2 1 RasGEF domain GRAM PF02893.20 EGC36836.1 - 3.7e-13 49.3 2.3 1.3e-12 47.6 2.3 2.0 1 0 0 1 1 1 1 GRAM domain RhoGAP PF00620.27 EGC36836.1 - 8.3e-08 32.2 0.2 1.3e-06 28.4 0.2 2.8 2 0 0 2 2 2 1 RhoGAP domain WD40 PF00400.32 EGC36837.1 - 0.0044 17.8 6.5 0.7 10.9 0.1 4.1 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF2442 PF10387.9 EGC36837.1 - 0.12 12.7 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2442) AMP-binding PF00501.28 EGC36838.1 - 6e-79 265.6 0.0 7e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC36838.1 - 7.3e-17 62.1 0.0 1.3e-16 61.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.13 EGC36838.1 - 0.00058 18.8 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Tfb2 PF03849.14 EGC36839.1 - 4.3e-118 394.4 8.8 5e-118 394.1 8.8 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Tfb2_C PF18307.1 EGC36839.1 - 5.6e-23 81.2 0.1 1.1e-22 80.3 0.1 1.5 1 0 0 1 1 1 1 Transcription factor Tfb2 (p52) C-terminal domain Helicase_C_3 PF13625.6 EGC36839.1 - 0.035 14.2 0.0 0.074 13.2 0.0 1.5 1 0 0 1 1 1 0 Helicase conserved C-terminal domain NatB_MDM20 PF09797.9 EGC36840.1 - 6.5e-92 308.4 17.2 6.5e-92 308.4 17.2 2.6 2 0 0 2 2 2 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_5 PF12688.7 EGC36840.1 - 0.0067 16.7 0.2 0.025 14.8 0.2 1.9 1 0 0 1 1 1 1 Tetratrico peptide repeat TPR_7 PF13176.6 EGC36840.1 - 0.015 15.3 0.2 0.33 11.1 0.1 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGC36840.1 - 0.02 15.7 0.0 17 6.6 0.0 4.6 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC36840.1 - 0.031 14.8 5.7 0.34 11.5 0.6 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC36840.1 - 0.032 14.1 3.1 1.6 8.7 0.3 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC36840.1 - 0.15 12.7 0.0 1.7 9.4 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC36840.1 - 0.16 12.2 1.4 24 5.4 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC36840.1 - 0.51 10.7 3.6 3.7 7.9 0.1 4.0 5 0 0 5 5 5 0 Tetratricopeptide repeat HEPN PF05168.14 EGC36840.1 - 0.55 10.4 4.0 1.5 8.9 0.2 3.3 3 0 0 3 3 3 0 HEPN domain Zn_ribbon_2 PF12674.7 EGC36840.1 - 4.3 8.1 8.3 0.91 10.2 1.1 3.6 3 1 1 4 4 3 0 Putative zinc ribbon domain TPR_8 PF13181.6 EGC36840.1 - 8.8 6.8 10.3 34 5.0 0.4 5.2 4 1 0 4 4 3 0 Tetratricopeptide repeat SpoU_methylase PF00588.19 EGC36841.1 - 2.8e-27 95.6 0.0 6.4e-27 94.5 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family eIF2_C PF09173.11 EGC36842.1 - 1.3e-34 118.2 0.2 3.6e-34 116.9 0.2 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU PF00009.27 EGC36842.1 - 2.4e-22 79.4 1.7 3.6e-21 75.6 1.7 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGC36842.1 - 2.7e-11 43.7 0.7 8.3e-11 42.1 0.7 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC36842.1 - 0.0071 16.4 0.0 0.014 15.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase MMR_HSR1_Xtn PF16897.5 EGC36842.1 - 0.012 15.6 0.2 0.028 14.4 0.2 1.6 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain RsgA_GTPase PF03193.16 EGC36842.1 - 0.017 15.0 0.5 0.16 11.8 0.1 2.2 2 0 0 2 2 2 0 RsgA GTPase Ribophorin_I PF04597.14 EGC36843.1 - 1.8e-127 426.2 14.4 2e-127 426.0 14.4 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L7Ae PF01248.26 EGC36844.1 - 7.1e-26 89.8 0.0 9.2e-26 89.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family PELOTA_1 PF15608.6 EGC36844.1 - 0.0018 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 PELOTA RNA binding domain RNase_P_pop3 PF08228.11 EGC36844.1 - 0.017 15.1 0.1 0.021 14.9 0.1 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 YadA_stalk PF05662.14 EGC36844.1 - 0.081 13.3 1.3 2.8 8.4 0.1 2.2 2 0 0 2 2 2 0 Coiled stalk of trimeric autotransporter adhesin FH2 PF02181.23 EGC36845.1 - 4.6e-70 236.6 27.5 8.7e-66 222.5 8.3 3.6 3 1 0 4 4 4 2 Formin Homology 2 Domain Drf_GBD PF06371.13 EGC36845.1 - 1.1e-47 162.0 10.0 1.1e-47 162.0 10.0 2.5 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGC36845.1 - 1.7e-18 66.9 0.2 1.7e-18 66.9 0.2 3.6 5 0 0 5 5 5 1 Diaphanous FH3 Domain ABC_membrane_3 PF13748.6 EGC36845.1 - 0.00099 18.4 0.1 0.0018 17.5 0.1 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region WD40 PF00400.32 EGC36846.1 - 3e-61 201.9 17.5 6.8e-11 42.6 0.5 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36846.1 - 4.9e-27 94.0 0.1 0.00015 22.0 0.0 6.3 1 1 5 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Tup_N PF08581.10 EGC36846.1 - 8.9e-25 86.8 13.7 8.9e-25 86.8 13.7 1.6 2 0 0 2 2 1 1 Tup N-terminal Ge1_WD40 PF16529.5 EGC36846.1 - 6.6e-12 45.0 0.1 0.11 11.5 0.1 5.5 1 1 4 5 5 5 4 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGC36846.1 - 2.1e-09 37.2 2.0 0.086 12.1 0.0 5.8 6 0 0 6 6 6 2 WD40-like domain eIF2A PF08662.11 EGC36846.1 - 2.9e-06 27.3 0.0 0.026 14.4 0.0 3.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PD40 PF07676.12 EGC36846.1 - 3.8e-06 26.7 5.3 2.2 8.3 0.0 5.8 6 0 0 6 6 6 2 WD40-like Beta Propeller Repeat Cytochrom_D1 PF02239.16 EGC36846.1 - 5.5e-06 25.2 0.6 0.0045 15.6 0.2 2.9 1 1 2 3 3 3 3 Cytochrome D1 heme domain Nbas_N PF15492.6 EGC36846.1 - 1.6e-05 24.4 0.2 0.4 10.0 0.0 3.6 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Frtz PF11768.8 EGC36846.1 - 7.1e-05 21.3 0.0 0.78 8.0 0.0 3.6 3 1 1 4 4 4 2 WD repeat-containing and planar cell polarity effector protein Fritz Nup160 PF11715.8 EGC36846.1 - 0.00027 19.7 0.1 6.6 5.3 0.0 4.4 2 1 2 5 5 5 2 Nucleoporin Nup120/160 BBP1_C PF15272.6 EGC36846.1 - 0.00058 19.8 4.9 0.00058 19.8 4.9 1.7 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal Nucleoporin_N PF08801.11 EGC36846.1 - 0.0043 15.9 0.2 2.1 7.0 0.1 3.7 2 2 1 3 3 3 1 Nup133 N terminal like nos_propeller PF18764.1 EGC36846.1 - 0.03 14.2 0.1 15 5.5 0.0 4.4 3 1 0 4 4 4 0 Nitrous oxide reductase propeller repeat CREPT PF16566.5 EGC36846.1 - 0.12 12.6 2.5 0.21 11.7 2.5 1.3 1 0 0 1 1 1 0 Cell-cycle alteration and expression-elevated protein in tumour DUF5122 PF17164.4 EGC36846.1 - 1.5 9.2 4.9 16 5.9 0.0 4.8 6 0 0 6 6 5 0 Domain of unknown function (DUF5122) beta-propeller Proteasome_A_N PF10584.9 EGC36846.1 - 5.8 6.7 10.7 83 3.0 0.0 5.2 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature Spc7 PF08317.11 EGC36846.1 - 8 5.2 16.9 0.032 13.1 7.3 1.7 2 0 0 2 2 2 0 Spc7 kinetochore protein URO-D PF01208.17 EGC36847.1 - 3.8e-131 437.4 0.0 4.3e-131 437.2 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Aldedh PF00171.22 EGC36848.1 - 2.5e-77 260.4 0.0 3.1e-77 260.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family OmpW PF03922.14 EGC36850.1 - 0.018 14.9 0.3 3.7 7.4 0.2 2.4 2 0 0 2 2 2 0 OmpW family F-box-like PF12937.7 EGC36850.1 - 0.13 12.2 0.0 0.5 10.3 0.0 2.1 2 0 0 2 2 2 0 F-box-like YEATS PF03366.16 EGC36851.1 - 1.3e-29 102.0 0.1 2.4e-29 101.1 0.1 1.4 1 0 0 1 1 1 1 YEATS family CCDC53 PF10152.9 EGC36851.1 - 0.0095 16.4 3.9 0.016 15.6 3.9 1.3 1 0 0 1 1 1 1 Subunit CCDC53 of WASH complex POT1 PF02765.17 EGC36851.1 - 0.11 12.4 2.5 0.7 9.7 1.5 2.2 2 0 0 2 2 2 0 Telomeric single stranded DNA binding POT1/CDC13 SOGA PF11365.8 EGC36851.1 - 0.22 12.7 3.3 0.5 11.5 2.8 1.7 1 1 1 2 2 2 0 Protein SOGA Mcm10 PF09332.11 EGC36851.1 - 0.27 10.6 6.0 0.35 10.2 6.0 1.2 1 0 0 1 1 1 0 Mcm10 replication factor ANAPC_CDC26 PF10471.9 EGC36852.1 - 4.5e-12 46.6 1.0 5.2e-12 46.4 1.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex APC subunit CDC26 AXH PF08517.12 EGC36852.1 - 0.022 15.3 0.1 0.023 15.2 0.1 1.0 1 0 0 1 1 1 0 Ataxin-1 and HBP1 module (AXH) TIP49 PF06068.13 EGC36854.1 - 5.6e-171 568.5 1.3 7.1e-171 568.1 1.3 1.1 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGC36854.1 - 6.4e-23 80.7 0.0 2e-22 79.1 0.0 1.9 1 0 0 1 1 1 1 TIP49 AAA-lid domain AAA PF00004.29 EGC36854.1 - 9.2e-12 45.5 0.4 1.8e-07 31.7 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGC36854.1 - 4e-10 39.7 0.3 1.3e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC36854.1 - 7.5e-07 29.5 0.2 0.028 14.7 0.0 2.7 2 2 0 2 2 2 2 AAA domain AAA_5 PF07728.14 EGC36854.1 - 2.8e-05 24.1 0.8 0.0069 16.4 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC36854.1 - 0.0002 21.8 0.0 0.0064 16.9 0.0 2.3 2 0 0 2 2 2 1 AAA ATPase domain Mg_chelatase PF01078.21 EGC36854.1 - 0.00081 18.8 0.3 0.04 13.3 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.26 EGC36854.1 - 0.0012 18.6 0.1 0.89 9.2 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.6 EGC36854.1 - 0.0014 18.2 0.4 0.0032 17.1 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC36854.1 - 0.0021 18.6 0.0 0.0079 16.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGC36854.1 - 0.0038 17.0 0.1 0.0092 15.7 0.1 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGC36854.1 - 0.0054 16.8 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain DnaB_C PF03796.15 EGC36854.1 - 0.0095 15.3 0.0 0.023 14.1 0.0 1.6 2 0 0 2 2 2 1 DnaB-like helicase C terminal domain AAA_28 PF13521.6 EGC36854.1 - 0.014 15.6 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_7 PF12775.7 EGC36854.1 - 0.017 14.6 0.2 0.092 12.2 0.0 2.2 2 0 0 2 2 2 0 P-loop containing dynein motor region ResIII PF04851.15 EGC36854.1 - 0.019 15.0 0.2 0.55 10.2 0.1 2.5 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit Zeta_toxin PF06414.12 EGC36854.1 - 0.022 14.0 0.3 0.055 12.7 0.3 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_11 PF13086.6 EGC36854.1 - 0.033 14.0 0.0 0.086 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain TsaE PF02367.17 EGC36854.1 - 0.067 13.2 0.1 0.14 12.1 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE PIF1 PF05970.14 EGC36854.1 - 0.072 12.2 0.0 6.6 5.8 0.0 2.3 2 0 0 2 2 2 0 PIF1-like helicase Rad17 PF03215.15 EGC36854.1 - 0.077 12.9 0.0 0.18 11.7 0.0 1.6 1 0 0 1 1 1 0 Rad17 P-loop domain AAA_19 PF13245.6 EGC36854.1 - 0.095 13.0 8.1 0.39 11.0 0.1 2.8 3 1 0 3 3 2 0 AAA domain NACHT PF05729.12 EGC36854.1 - 0.14 12.1 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DTW PF03942.15 EGC36855.1 - 1.5e-24 86.8 0.0 3e-24 85.8 0.0 1.5 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.24 EGC36855.1 - 0.028 14.6 4.5 0.049 13.8 4.5 1.4 1 0 0 1 1 1 0 B-box zinc finger Pox_Ag35 PF03286.14 EGC36855.1 - 0.7 9.7 6.2 0.98 9.2 6.2 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Rap_GAP PF02145.15 EGC36856.1 - 3.1e-57 193.1 0.1 4.5e-57 192.6 0.1 1.3 1 0 0 1 1 1 1 Rap/ran-GAP PALP PF00291.25 EGC36858.1 - 1e-48 166.3 0.0 1.4e-48 165.8 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Wbp11 PF09429.10 EGC36859.1 - 2.3e-08 34.3 21.0 2.3e-08 34.3 21.0 2.2 2 1 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.7 EGC36859.1 - 1.2e-07 32.3 12.9 1.2e-07 32.3 12.9 5.9 2 2 1 3 3 3 1 mRNA biogenesis factor DUF572 PF04502.13 EGC36859.1 - 0.19 11.3 18.3 0.099 12.3 5.2 2.0 2 0 0 2 2 2 0 Family of unknown function (DUF572) MGC-24 PF05283.11 EGC36859.1 - 4.7 7.6 12.1 8.4 6.8 12.1 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin PAC1 PF16094.5 EGC36860.1 - 2.6e-20 72.7 5.6 8.4e-20 71.1 5.6 1.7 1 1 0 1 1 1 1 Proteasome assembly chaperone 4 Secretin_N_2 PF07655.13 EGC36861.1 - 4.5 7.9 17.6 22 5.7 17.6 2.2 1 0 0 1 1 1 0 Secretin N-terminal domain ELMO_CED12 PF04727.13 EGC36862.1 - 2.9e-35 121.9 1.0 1.2e-34 120.0 1.0 2.2 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase PF00069.25 EGC36864.1 - 8.2e-06 25.4 0.2 1.2e-05 24.9 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36864.1 - 1e-05 25.0 0.1 1.5e-05 24.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF21 PF01595.20 EGC36866.1 - 9e-35 119.9 1.5 1.4e-34 119.3 1.5 1.2 1 0 0 1 1 1 1 Cyclin M transmembrane N-terminal domain CBS PF00571.28 EGC36866.1 - 0.002 18.5 0.1 1.3 9.6 0.0 2.6 2 0 0 2 2 2 2 CBS domain cNMP_binding PF00027.29 EGC36866.1 - 0.046 13.8 0.0 0.099 12.7 0.0 1.5 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain FEZ PF07763.13 EGC36866.1 - 0.13 12.0 0.8 0.21 11.3 0.0 1.7 2 0 0 2 2 2 0 FEZ-like protein Halogen_Hydrol PF10112.9 EGC36866.1 - 3.2 7.8 5.1 0.35 10.9 0.2 1.9 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein WD40 PF00400.32 EGC36867.1 - 1.3e-30 104.9 22.5 1.9e-05 25.3 0.3 6.5 6 0 0 6 6 6 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC36867.1 - 0.0019 18.5 1.2 0.47 10.8 0.1 3.0 3 1 0 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain zf-HIT PF04438.16 EGC36868.1 - 6.5e-10 38.7 10.7 1.2e-09 37.9 10.7 1.5 1 0 0 1 1 1 1 HIT zinc finger Spt46 PF17734.1 EGC36868.1 - 0.077 12.8 0.9 0.13 12.0 0.9 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated protein 46 zf-MYND PF01753.18 EGC36868.1 - 0.9 9.7 10.6 1.7 8.8 10.6 1.5 1 0 0 1 1 1 0 MYND finger DBD_Tnp_Hermes PF10683.9 EGC36869.1 - 0.078 12.7 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain PBP1_TM PF14812.6 EGC36869.1 - 0.74 10.2 4.8 3.6 8.0 4.8 2.2 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal TAXi_C PF14541.6 EGC36870.1 - 1.2e-15 57.7 1.3 1.3e-15 57.5 0.1 1.8 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TSP_1 PF00090.19 EGC36870.1 - 0.0026 17.9 3.1 0.0026 17.9 3.1 4.3 5 1 0 5 5 5 2 Thrombospondin type 1 domain Nrf1_DNA-bind PF10491.9 EGC36870.1 - 0.053 13.2 0.0 0.092 12.4 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 FNIP PF05725.12 EGC36871.1 - 7.6e-41 138.0 59.4 8.3e-10 38.7 1.9 9.4 3 2 8 12 12 12 10 FNIP Repeat Aft1_OSA PF11785.8 EGC36873.1 - 0.09 13.2 1.9 0.22 12.0 1.9 1.7 1 0 0 1 1 1 0 Aft1 osmotic stress response (OSM) domain Sedlin_N PF04628.13 EGC36874.1 - 8.5e-36 123.0 0.8 9.6e-36 122.8 0.8 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.12 EGC36874.1 - 9.7e-06 25.6 0.4 1.1e-05 25.4 0.4 1.1 1 0 0 1 1 1 1 Sybindin-like family Dus PF01207.17 EGC36875.1 - 6.5e-57 193.0 0.0 1e-56 192.3 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH_4 PF18044.1 EGC36875.1 - 1e-06 28.4 7.3 0.00015 21.5 0.2 2.7 2 0 0 2 2 2 2 CCCH-type zinc finger zf-CCCH PF00642.24 EGC36875.1 - 0.00092 19.1 10.4 0.015 15.2 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.6 EGC36875.1 - 0.0022 18.4 8.6 0.25 11.9 0.8 2.7 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger zf_CCCH_4 PF18345.1 EGC36875.1 - 0.014 15.5 13.8 0.016 15.3 2.2 2.6 2 0 0 2 2 2 0 Zinc finger domain Asp-B-Hydro_N PF05279.11 EGC36875.1 - 0.12 12.4 10.9 0.18 11.8 10.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region EBP50_C PF09007.11 EGC36875.1 - 0.97 10.4 11.4 2.5 9.1 11.4 1.7 1 0 0 1 1 1 0 EBP50, C-terminal Presenilin PF01080.17 EGC36875.1 - 2.5 6.8 7.9 3.3 6.4 7.9 1.1 1 0 0 1 1 1 0 Presenilin zf-CCHH PF10283.9 EGC36875.1 - 5.5 7.1 9.4 5.4 7.1 1.5 2.6 2 0 0 2 2 2 0 PBZ domain Atrophin-1 PF03154.15 EGC36875.1 - 7.1 4.8 10.9 9.4 4.4 10.9 1.1 1 0 0 1 1 1 0 Atrophin-1 family Sporozoite_P67 PF05642.11 EGC36875.1 - 8.6 4.3 11.5 14 3.6 11.5 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PARP PF00644.20 EGC36876.1 - 1.9e-60 203.8 0.0 1.9e-60 203.8 0.0 2.9 2 1 1 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC36876.1 - 3.3e-42 143.8 4.7 8.4e-42 142.5 4.7 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGC36876.1 - 2.2e-20 72.5 2.6 6.4e-20 71.0 2.6 1.9 1 0 0 1 1 1 1 WGR domain BRCT PF00533.26 EGC36876.1 - 1.5e-11 44.5 1.2 5.5e-11 42.7 1.2 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC36876.1 - 2.7e-05 24.5 2.8 6e-05 23.4 0.8 2.6 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC36876.1 - 0.00021 21.1 0.1 0.00041 20.2 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Pap_E4 PF02711.14 EGC36876.1 - 0.034 15.1 3.5 0.041 14.9 1.4 2.3 2 0 0 2 2 2 0 E4 protein TFIIF_alpha PF05793.12 EGC36876.1 - 0.17 10.4 32.1 0.0063 15.2 26.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CDC45 PF02724.14 EGC36876.1 - 3 6.0 15.4 4.7 5.4 15.4 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGC36876.1 - 6.9 5.3 7.8 13 4.4 7.8 1.5 1 0 0 1 1 1 0 Presenilin Zip PF02535.22 EGC36876.1 - 8.2 5.5 6.7 20 4.3 6.7 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_A22B PF04258.13 EGC36877.1 - 1.8e-90 303.3 11.8 2.4e-90 302.9 11.8 1.1 1 0 0 1 1 1 1 Signal peptide peptidase SPP PF06550.11 EGC36877.1 - 0.00058 19.4 11.3 0.0064 16.0 11.3 2.4 1 1 0 1 1 1 1 Signal-peptide peptidase, presenilin aspartyl protease DUF2391 PF09622.10 EGC36877.1 - 0.0079 15.6 0.2 0.016 14.6 0.2 1.5 1 0 0 1 1 1 1 Putative integral membrane protein (DUF2391) TM140 PF14985.6 EGC36877.1 - 0.24 10.9 0.1 0.24 10.9 0.1 2.8 3 1 1 4 4 4 0 TM140 protein family FNIP PF05725.12 EGC36878.1 - 7e-66 218.2 72.5 1.2e-14 54.2 2.6 10.0 1 1 9 12 12 12 11 FNIP Repeat cPLA2_C2 PF18695.1 EGC36878.1 - 0.017 15.1 0.0 0.05 13.6 0.0 1.8 1 0 0 1 1 1 0 Cytosolic phospholipases A2 C2-domain TFIID-18kDa PF02269.16 EGC36879.1 - 9.3e-32 108.9 1.5 1.1e-31 108.7 1.5 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.23 EGC36879.1 - 0.02 15.1 0.1 0.05 13.9 0.1 1.7 1 1 1 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF202 PF02656.15 EGC36880.1 - 9.9e-05 22.7 0.7 9.9e-05 22.7 0.7 1.5 2 0 0 2 2 2 1 Domain of unknown function (DUF202) PYRIN PF02758.16 EGC36880.1 - 0.026 14.7 0.8 0.065 13.4 0.8 1.7 1 0 0 1 1 1 0 PAAD/DAPIN/Pyrin domain TssN PF17555.2 EGC36880.1 - 0.18 11.1 3.3 0.32 10.3 3.3 1.4 1 0 0 1 1 1 0 Type VI secretion system, TssN RAMP4 PF06624.12 EGC36880.1 - 0.25 11.4 0.1 0.25 11.4 0.1 3.5 4 0 0 4 4 4 0 Ribosome associated membrane protein RAMP4 bZIP_1 PF00170.21 EGC36881.1 - 8.2 6.6 10.9 3.4 7.8 4.3 3.4 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.25 EGC36882.1 - 2.5e-12 46.7 0.9 4.2e-12 46.0 0.9 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36882.1 - 7.9e-08 31.9 0.1 1.2e-07 31.3 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGC36882.1 - 5.4e-05 22.9 0.3 0.00011 21.9 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGC36882.1 - 0.00034 20.6 0.2 0.00062 19.8 0.2 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.11 EGC36882.1 - 0.0044 16.1 0.3 0.0075 15.4 0.3 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.14 EGC36882.1 - 0.0064 15.9 0.1 0.011 15.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.20 EGC36882.1 - 0.021 14.4 0.8 0.041 13.5 0.8 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGC36882.1 - 0.04 12.7 0.1 0.052 12.3 0.1 1.1 1 0 0 1 1 1 0 Fungal protein kinase Haspin_kinase PF12330.8 EGC36882.1 - 0.12 11.3 0.9 0.18 10.7 0.9 1.2 1 0 0 1 1 1 0 Haspin like kinase domain OrfB_Zn_ribbon PF07282.11 EGC36882.1 - 1.6 8.7 7.1 0.91 9.5 4.7 1.9 2 0 0 2 2 2 0 Putative transposase DNA-binding domain FH2 PF02181.23 EGC36883.1 - 3.1e-89 299.7 10.9 3.1e-89 299.7 10.9 2.9 4 0 0 4 4 4 2 Formin Homology 2 Domain Drf_GBD PF06371.13 EGC36883.1 - 5.4e-45 153.3 0.5 5.4e-45 153.3 0.5 4.3 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.16 EGC36883.1 - 9.4e-38 129.8 0.8 9.4e-38 129.8 0.8 3.7 2 2 0 3 3 3 1 Diaphanous FH3 Domain C2 PF00168.30 EGC36883.1 - 2.1e-10 40.8 0.1 8e-10 38.9 0.1 2.1 1 0 0 1 1 1 1 C2 domain ADIP PF11559.8 EGC36883.1 - 0.0054 16.8 9.2 0.0054 16.8 9.2 3.4 4 0 0 4 4 4 1 Afadin- and alpha -actinin-Binding AsnC_trans_reg PF01037.21 EGC36883.1 - 0.067 13.2 0.1 0.28 11.2 0.1 2.1 1 0 0 1 1 1 0 Lrp/AsnC ligand binding domain TINF2_N PF14973.6 EGC36883.1 - 0.22 11.8 0.1 0.22 11.8 0.1 3.3 3 1 0 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus BCDHK_Adom3 PF10436.9 EGC36884.1 - 0.013 15.4 0.7 0.013 15.4 0.7 2.7 2 1 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase CPSF100_C PF13299.6 EGC36884.1 - 0.88 9.7 13.0 2 8.6 5.8 2.6 2 0 0 2 2 2 0 Cleavage and polyadenylation factor 2 C-terminal Tim54 PF11711.8 EGC36884.1 - 1.5 7.5 9.5 0.11 11.2 2.7 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RPN2_C PF18004.1 EGC36884.1 - 2.3 8.1 25.5 0.16 11.9 0.9 2.7 3 0 0 3 3 3 0 26S proteasome regulatory subunit RPN2 C-terminal domain RPA43_OB PF17875.1 EGC36884.1 - 4.8 7.8 9.3 1.4 9.5 2.7 3.0 3 0 0 3 3 3 0 RPA43 OB domain in RNA Pol I Stk19 PF10494.9 EGC36885.1 - 2.7e-22 79.6 0.9 4.5e-22 78.9 0.9 1.3 1 0 0 1 1 1 1 Serine-threonine protein kinase 19 INTAP PF16617.5 EGC36885.1 - 1.9 8.9 5.2 0.24 11.8 0.6 1.9 2 0 0 2 2 2 0 Intersectin and clathrin adaptor AP2 binding region p450 PF00067.22 EGC36886.1 - 5e-79 266.2 0.0 8.9e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Trs65 PF12735.7 EGC36886.1 - 0.00015 21.3 8.0 0.00015 21.3 8.0 4.9 3 2 2 5 5 5 1 TRAPP trafficking subunit Trs65 Cornichon PF03311.14 EGC36887.1 - 1.4e-35 122.2 9.5 1.8e-35 121.9 9.5 1.0 1 0 0 1 1 1 1 Cornichon protein PUF PF00806.19 EGC36888.1 - 2.1e-70 228.6 24.2 3.4e-10 39.0 0.9 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat sCache_2 PF17200.4 EGC36888.1 - 0.00043 20.2 0.2 4.2 7.2 0.0 4.1 4 1 1 5 5 5 2 Single Cache domain 2 TBPIP PF07106.13 EGC36888.1 - 0.01 15.7 2.3 3.2 7.8 0.1 4.3 4 1 0 5 5 5 0 TBPIP/Hop2 winged helix domain DNA_pol3_delta2 PF13177.6 EGC36888.1 - 0.043 13.6 0.1 0.095 12.5 0.1 1.7 1 0 0 1 1 1 0 DNA polymerase III, delta subunit MIF4G PF02854.19 EGC36888.1 - 0.071 12.7 2.7 0.49 10.0 0.2 2.8 2 1 1 3 3 3 0 MIF4G domain SANTA PF09133.10 EGC36888.1 - 0.074 13.5 1.9 24 5.5 0.0 3.5 2 1 1 3 3 3 0 SANTA (SANT Associated) Ribosomal_S10 PF00338.22 EGC36889.1 - 3.9e-25 87.9 0.1 4.5e-25 87.7 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e YlbE PF14003.6 EGC36889.1 - 0.12 12.8 0.1 0.19 12.2 0.1 1.3 1 0 0 1 1 1 0 YlbE-like protein FNIP PF05725.12 EGC36890.1 - 4.6e-05 23.5 45.9 0.023 14.9 0.1 8.9 7 3 2 10 10 10 6 FNIP Repeat LRR_4 PF12799.7 EGC36890.1 - 0.048 14.1 0.4 0.048 14.1 0.4 8.3 8 2 2 10 10 10 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC36890.1 - 1 10.1 0.0 1 10.1 0.0 5.9 7 1 0 7 7 7 0 Leucine Rich Repeat Cob_adeno_trans PF01923.18 EGC36892.1 - 0.0032 17.6 0.1 0.0048 17.0 0.1 1.3 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF596 PF04591.12 EGC36892.1 - 0.11 12.6 0.0 0.24 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 SPX PF03105.19 EGC36892.1 - 0.82 9.5 34.0 0.99 9.3 7.3 2.1 2 0 0 2 2 2 0 SPX domain Fib_alpha PF08702.10 EGC36892.1 - 7 6.8 15.8 12 6.1 14.5 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family RNase_PH PF01138.21 EGC36893.1 - 3e-26 92.5 0.0 4.8e-26 91.8 0.0 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGC36893.1 - 1.9e-15 56.6 0.0 4e-15 55.6 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3124 PF11322.8 EGC36893.1 - 0.071 13.3 0.1 8.6 6.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3124) COMM_domain PF07258.14 EGC36894.1 - 9.4e-13 48.1 4.5 1.8e-12 47.2 4.5 1.5 1 0 0 1 1 1 1 COMM domain MCM PF00493.23 EGC36895.1 - 2.3e-98 327.7 0.1 5.3e-98 326.6 0.0 1.7 2 0 0 2 2 2 1 MCM P-loop domain MCM_OB PF17207.3 EGC36895.1 - 8.8e-36 122.5 0.8 1.4e-35 121.8 0.8 1.3 1 0 0 1 1 1 1 MCM OB domain MCM_lid PF17855.1 EGC36895.1 - 2.3e-27 95.2 3.0 5.1e-27 94.1 3.0 1.6 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_N PF14551.6 EGC36895.1 - 2.2e-14 53.9 2.5 5.7e-14 52.6 2.5 1.7 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.21 EGC36895.1 - 3.8e-06 26.4 0.0 0.0015 18.0 0.0 2.5 1 1 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC36895.1 - 1e-05 25.5 0.0 2.7e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGC36895.1 - 0.002 18.0 0.0 0.0052 16.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC36895.1 - 0.021 14.5 0.1 0.19 11.4 0.1 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.29 EGC36895.1 - 0.027 14.9 1.8 7.8 6.9 0.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Pro_isomerase PF00160.21 EGC36897.1 - 2.1e-52 177.6 0.0 4.8e-52 176.4 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD zf-NOSIP PF15906.5 EGC36897.1 - 1.8e-05 24.8 0.0 8.1e-05 22.7 0.0 2.2 2 0 0 2 2 2 1 Zinc-finger of nitric oxide synthase-interacting protein Rtf2 PF04641.12 EGC36897.1 - 7.5e-05 22.2 18.8 7.5e-05 22.2 18.8 3.7 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.15 EGC36897.1 - 0.002 18.2 1.0 0.012 15.8 0.0 2.9 3 1 1 4 4 4 1 U-box domain zf-Nse PF11789.8 EGC36897.1 - 0.003 17.3 0.5 0.016 15.0 0.1 2.3 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Glyco_hydro_77 PF02446.17 EGC36898.1 - 3e-158 527.5 2.6 4.1e-158 527.1 2.6 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.19 EGC36898.1 - 4e-40 135.6 5.3 8.3e-21 73.7 0.5 2.7 2 0 0 2 2 2 2 Starch binding domain DUF3395 PF11875.8 EGC36899.1 - 2.3e-42 144.5 1.2 1.5e-41 141.9 2.1 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3395) DnaJ PF00226.31 EGC36899.1 - 1e-19 70.4 1.2 3.2e-19 68.8 1.2 1.9 1 0 0 1 1 1 1 DnaJ domain SAP PF02037.27 EGC36900.1 - 4.4e-05 23.1 4.9 6.1e-05 22.7 2.2 2.3 2 0 0 2 2 2 1 SAP domain HeH PF12949.7 EGC36900.1 - 9e-05 22.1 0.0 0.00022 20.9 0.0 1.6 1 0 0 1 1 1 1 HeH/LEM domain UBA_2 PF08587.11 EGC36900.1 - 0.26 11.4 2.5 0.57 10.3 0.4 2.5 2 0 0 2 2 2 0 Ubiquitin associated domain (UBA) Pyrophosphatase PF00719.19 EGC36901.1 - 1.9e-49 167.6 0.1 2.3e-49 167.3 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase BSD PF03909.17 EGC36902.1 - 2.2e-06 27.6 0.9 1.2e-05 25.2 0.9 2.3 1 0 0 1 1 1 1 BSD domain DUF719 PF05334.13 EGC36902.1 - 0.06 13.6 0.1 0.06 13.6 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF719) IBR PF01485.21 EGC36903.1 - 0.00086 19.5 7.7 0.00086 19.5 7.7 4.5 3 1 1 4 4 4 1 IBR domain, a half RING-finger domain zf-C3HC4 PF00097.25 EGC36903.1 - 0.0012 18.7 10.6 0.0012 18.7 10.6 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC36903.1 - 0.0043 16.9 7.5 0.0043 16.9 7.5 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC36903.1 - 0.0079 16.5 10.5 0.0079 16.5 10.5 3.5 2 1 1 3 3 3 1 Ring finger domain C1_4 PF07975.12 EGC36903.1 - 0.086 13.1 20.5 0.069 13.4 7.4 3.4 2 0 0 2 2 2 0 TFIIH C1-like domain zf-RING_UBOX PF13445.6 EGC36903.1 - 0.96 9.5 14.2 0.31 11.1 9.5 2.7 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_11 PF17123.5 EGC36903.1 - 4.3 7.2 13.8 1.9 8.3 10.3 2.4 2 0 0 2 2 2 0 RING-like zinc finger Myb_DNA-binding PF00249.31 EGC36904.1 - 6.7e-34 115.8 5.4 2e-17 63.1 0.3 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC36904.1 - 3.8e-28 97.5 4.0 6.3e-18 64.8 0.3 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.10 EGC36904.1 - 1.8e-07 31.2 0.2 0.002 18.1 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_7 PF15963.5 EGC36904.1 - 1.3e-05 25.0 0.4 0.0036 17.2 0.1 2.0 1 1 1 2 2 2 2 Myb DNA-binding like SANT_DAMP1_like PF16282.5 EGC36904.1 - 0.0093 16.1 0.9 2.5 8.4 0.1 2.1 1 1 1 2 2 2 2 SANT/Myb-like domain of DAMP1 DUF5409 PF17421.2 EGC36904.1 - 0.01 16.5 0.0 0.016 15.9 0.0 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5409) Myb_DNA-bind_5 PF13873.6 EGC36904.1 - 0.13 12.3 4.5 63 3.7 0.0 4.0 1 1 3 4 4 4 0 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.6 EGC36904.1 - 0.14 12.5 6.0 3.2 8.2 1.9 3.2 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CENP-S PF15630.6 EGC36905.1 - 4.4e-25 87.9 0.5 4.4e-25 87.9 0.5 1.8 2 0 0 2 2 2 1 CENP-S protein CENP-T_C PF15511.6 EGC36905.1 - 7.1e-07 29.3 0.1 1.5e-06 28.2 0.1 1.6 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold TFIID-31kDa PF02291.15 EGC36905.1 - 0.016 15.2 0.0 0.036 14.1 0.0 1.5 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit Erf4 PF10256.9 EGC36906.1 - 1.1e-19 70.6 1.0 1.3e-13 51.1 0.1 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF4381 PF14316.6 EGC36906.1 - 0.00075 19.8 0.1 0.82 9.9 0.0 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4381) DUF5313 PF17240.2 EGC36906.1 - 0.21 12.0 4.4 0.4 11.1 0.1 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5313) DUF2207 PF09972.9 EGC36906.1 - 0.23 10.2 1.9 5.4 5.7 0.2 2.1 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) Vpu PF00558.19 EGC36906.1 - 0.45 10.3 5.1 4.4 7.1 0.1 2.4 2 0 0 2 2 2 0 Vpu protein Phage_Gp23 PF10669.9 EGC36906.1 - 4 7.8 4.5 8.9 6.7 0.1 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) DER1 PF04511.15 EGC36907.1 - 2.4e-54 184.2 16.3 2.7e-54 184.0 16.3 1.0 1 0 0 1 1 1 1 Der1-like family DUF1331 PF07048.11 EGC36907.1 - 0.024 14.3 0.1 0.091 12.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DUF4133 PF13571.6 EGC36907.1 - 0.032 14.6 0.5 0.032 14.6 0.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Glyco_hydro_9 PF00759.19 EGC36908.1 - 2.1e-125 419.4 6.3 2.4e-125 419.2 6.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PTR2 PF00854.21 EGC36909.1 - 4e-98 328.8 6.2 5.6e-98 328.4 6.2 1.1 1 0 0 1 1 1 1 POT family MFS_1 PF07690.16 EGC36909.1 - 3.8e-12 45.8 18.7 8.2e-11 41.4 10.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily CbiM PF01891.16 EGC36909.1 - 0.018 14.9 0.1 0.018 14.9 0.1 3.0 4 0 0 4 4 4 0 Cobalt uptake substrate-specific transmembrane region Phage_holin_3_6 PF07332.11 EGC36909.1 - 1.9 8.6 6.5 1.5 8.8 0.1 2.9 3 1 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4149 PF13664.6 EGC36909.1 - 2.3 8.6 7.1 3.3 8.1 3.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4149) Mob_synth_C PF06463.13 EGC36910.1 - 4.5e-40 136.5 0.4 9.6e-40 135.5 0.1 1.8 2 0 0 2 2 2 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.21 EGC36910.1 - 8.1e-27 94.6 0.3 1.4e-26 93.8 0.3 1.4 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.6 EGC36910.1 - 1.6e-08 34.9 0.7 4.5e-08 33.4 0.1 2.0 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_14 PF13394.6 EGC36910.1 - 1e-06 28.9 0.6 3.8e-06 27.0 0.1 2.2 2 0 0 2 2 2 1 4Fe-4S single cluster domain MoaC PF01967.21 EGC36911.1 - 1.5e-48 164.4 2.0 1.7e-48 164.1 2.0 1.1 1 0 0 1 1 1 1 MoaC family GATA PF00320.27 EGC36912.1 - 4.4e-17 61.4 3.9 1.1e-16 60.2 3.9 1.7 1 0 0 1 1 1 1 GATA zinc finger Glyoxalase PF00903.25 EGC36913.1 - 1.7e-21 76.8 0.0 1.9e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGC36913.1 - 9.1e-09 35.6 0.0 7.2e-08 32.7 0.0 1.9 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_6 PF18029.1 EGC36913.1 - 0.00013 22.8 0.0 0.00019 22.2 0.0 1.4 1 1 0 1 1 1 1 Glyoxalase-like domain CppA_N PF14506.6 EGC36913.1 - 0.013 15.6 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Glyoxalase_2 PF12681.7 EGC36913.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 1 0 1 1 1 0 Glyoxalase-like domain RhoGAP PF00620.27 EGC36914.1 - 1.2e-29 103.1 0.0 1.2e-29 103.1 0.0 2.7 3 1 1 4 4 4 1 RhoGAP domain DUF4972 PF16342.5 EGC36914.1 - 0.012 15.3 1.5 0.012 15.3 1.5 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) DUF1479 PF07350.12 EGC36916.1 - 4.4e-13 48.8 0.3 2.2e-08 33.3 0.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.13 EGC36916.1 - 2.7e-05 24.5 0.1 0.0083 16.4 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) HSP20 PF00011.21 EGC36917.1 - 1.7e-14 53.8 3.1 3.3e-07 30.4 0.0 2.4 1 1 0 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC36917.1 - 0.0075 15.8 0.1 0.17 11.5 0.1 2.3 2 1 0 2 2 2 1 HSP20-like domain found in ArsA gp45-slide_C PF09116.10 EGC36917.1 - 0.26 11.4 2.7 9.9 6.3 0.2 2.7 1 1 2 3 3 3 0 gp45 sliding clamp, C terminal Diphthamide_syn PF01866.17 EGC36918.1 - 7.1e-122 406.6 0.0 9.6e-122 406.2 0.0 1.2 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CBM49 PF09478.10 EGC36919.1 - 9.3e-13 48.3 0.7 1.5e-12 47.6 0.7 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 eIF2A PF08662.11 EGC36920.1 - 1.3e-65 221.0 1.5 4.9e-64 215.8 0.0 2.7 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A CDV3 PF15359.6 EGC36920.1 - 1.7 9.1 9.7 1.4 9.4 1.0 2.3 2 0 0 2 2 2 0 Carnitine deficiency-associated protein 3 RCC1 PF00415.18 EGC36921.1 - 1.8e-57 191.8 3.5 4.5e-12 46.4 0.2 7.8 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC36921.1 - 7.8e-36 121.1 17.5 1e-06 28.4 1.1 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat CDC24_OB1 PF17246.2 EGC36922.1 - 3.9e-27 94.8 4.9 3.9e-27 94.8 4.9 3.9 3 1 0 3 3 3 1 Cell division control protein 24, OB domain 1 CDC24_OB3 PF17244.2 EGC36922.1 - 6.4e-17 62.0 0.5 6.4e-17 62.0 0.5 2.0 2 0 0 2 2 2 1 Cell division control protein 24, OB domain 3 DUF1910 PF08928.10 EGC36922.1 - 0.013 15.5 0.2 0.013 15.5 0.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Zip PF02535.22 EGC36922.1 - 0.45 9.7 3.8 0.78 8.9 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC36922.1 - 8.4 5.0 11.8 17 4.0 11.8 1.4 1 0 0 1 1 1 0 Presenilin STT3 PF02516.14 EGC36923.1 - 3.1e-130 435.4 43.3 7.9e-126 420.8 39.9 2.0 2 0 0 2 2 2 2 Oligosaccharyl transferase STT3 subunit SNF2_N PF00176.23 EGC36924.1 - 1.6e-69 234.3 0.4 1.6e-69 234.3 0.4 2.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC36924.1 - 3e-17 62.9 5.9 6.4e-16 58.7 0.0 4.3 5 0 0 5 5 5 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC36924.1 - 2.6e-10 40.6 0.0 2.6e-10 40.6 0.0 4.7 4 1 1 5 5 5 1 Type III restriction enzyme, res subunit QLQ PF08880.11 EGC36924.1 - 1.1e-05 25.0 0.3 1.1e-05 25.0 0.3 2.1 2 0 0 2 2 2 1 QLQ HSA PF07529.13 EGC36924.1 - 0.0028 17.9 3.2 0.0028 17.9 3.2 4.2 5 0 0 5 5 5 1 HSA SnAC PF14619.6 EGC36924.1 - 0.0086 16.7 5.7 0.0086 16.7 5.7 3.7 2 1 1 3 3 3 1 Snf2-ATP coupling, chromatin remodelling complex C1_1 PF00130.22 EGC36925.1 - 0.01 15.7 4.8 0.01 15.7 4.8 1.7 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.22 EGC36925.1 - 5.6 7.3 14.5 0.052 13.8 5.9 2.1 2 1 0 2 2 2 0 LIM domain ThiS PF02597.20 EGC36926.1 - 7.6e-14 52.1 0.0 9.1e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ThiS family 40S_S4_C PF16121.5 EGC36926.1 - 0.08 12.6 0.1 0.13 11.9 0.1 1.3 1 0 0 1 1 1 0 40S ribosomal protein S4 C-terminus CBM49 PF09478.10 EGC36927.1 - 3.3e-15 56.2 0.3 4.7e-15 55.7 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 MAS20 PF02064.15 EGC36928.1 - 0.092 12.8 0.2 0.13 12.3 0.2 1.2 1 0 0 1 1 1 0 MAS20 protein import receptor Oxysterol_BP PF01237.18 EGC36929.1 - 9.2e-64 215.6 13.6 4.3e-60 203.5 1.6 2.0 1 1 1 2 2 2 2 Oxysterol-binding protein GramPos_pilinD3 PF16570.5 EGC36929.1 - 0.027 15.2 0.4 0.062 14.0 0.4 1.7 1 0 0 1 1 1 0 Gram-positive pilin backbone subunit 3, Cna-B-like domain FNIP PF05725.12 EGC36930.1 - 2.1e-11 43.8 89.4 0.027 14.6 0.2 13.3 9 4 2 11 11 11 9 FNIP Repeat SOCS_box PF07525.16 EGC36930.1 - 1.2 9.5 3.9 28 5.2 0.3 3.9 3 0 0 3 3 3 0 SOCS box zf-TRAF PF02176.18 EGC36932.1 - 2.8e-14 53.5 25.2 8e-10 39.3 12.8 4.9 2 1 3 5 5 5 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC36932.1 - 5e-07 29.5 11.8 5e-07 29.5 11.8 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC36932.1 - 9.8e-07 28.9 9.7 0.00022 21.2 1.9 3.5 1 1 3 4 4 4 2 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC36932.1 - 1.2e-06 28.2 12.6 1.2e-06 28.2 12.6 4.1 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC36932.1 - 0.0031 17.9 4.5 0.0031 17.9 4.5 3.8 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC36932.1 - 0.034 14.5 13.1 0.034 14.5 13.1 4.3 3 1 1 4 4 4 0 Ring finger domain FNIP PF05725.12 EGC36933.1 - 0.0012 18.9 0.6 0.0012 18.9 0.6 9.5 9 2 0 9 9 9 5 FNIP Repeat FNIP PF05725.12 EGC36934.1 - 8.8e-19 67.4 32.1 8.3e-09 35.5 0.3 9.2 5 3 3 8 8 8 7 FNIP Repeat Recep_L_domain PF01030.24 EGC36934.1 - 0.0014 18.7 2.6 0.02 15.0 0.3 3.4 2 1 0 2 2 2 1 Receptor L domain HSP20 PF00011.21 EGC36935.1 - 1e-15 57.7 0.3 1.9e-15 56.9 0.3 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC36935.1 - 3.6e-06 26.4 0.0 7.9e-06 25.3 0.0 1.6 1 1 0 1 1 1 1 HSP20-like domain found in ArsA FKBP26_C PF18046.1 EGC36935.1 - 0.0016 18.5 1.0 0.27 11.3 0.1 2.2 2 0 0 2 2 2 2 FKBP26_C-terminal CS PF04969.16 EGC36935.1 - 0.097 13.7 2.2 0.44 11.6 2.2 2.1 1 1 0 1 1 1 0 CS domain Cyclin PF08613.11 EGC36936.1 - 9.2e-33 113.9 0.3 9.2e-33 113.9 0.3 3.1 2 1 1 3 3 3 1 Cyclin Cyclin_N PF00134.23 EGC36936.1 - 1.5e-09 37.7 0.0 2.4e-09 37.0 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Ashwin PF15323.6 EGC36936.1 - 3.6 7.6 17.8 5.2 7.0 17.8 1.2 1 0 0 1 1 1 0 Developmental protein DUF1117 PF06547.12 EGC36936.1 - 6.1 7.4 5.7 12 6.5 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1117) Methyltransf_2 PF00891.18 EGC36938.1 - 6.7e-40 136.6 0.0 9.7e-40 136.1 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_23 PF13489.6 EGC36938.1 - 0.0017 18.2 0.0 0.0055 16.5 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EGC36938.1 - 0.11 12.0 0.1 0.31 10.5 0.1 1.7 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase HTH_Crp_2 PF13545.6 EGC36938.1 - 0.16 12.0 0.0 0.31 11.1 0.0 1.4 1 0 0 1 1 1 0 Crp-like helix-turn-helix domain Methyltransf_2 PF00891.18 EGC36939.1 - 1.2e-21 77.1 0.0 7.8e-11 41.7 0.0 2.2 1 1 1 2 2 2 2 O-methyltransferase domain Phage_T7_Capsid PF05396.11 EGC36939.1 - 0.065 13.6 0.0 0.17 12.2 0.0 1.7 2 0 0 2 2 2 0 Phage T7 capsid assembly protein KBP_C PF12309.8 EGC36940.1 - 5.7e-44 151.1 18.1 2.5e-42 145.7 11.0 3.3 2 2 0 2 2 2 1 KIF-1 binding protein C terminal ArdA PF07275.11 EGC36940.1 - 0.058 14.0 0.5 0.058 14.0 0.5 2.8 2 1 0 3 3 3 0 Antirestriction protein (ArdA) TPR_12 PF13424.6 EGC36940.1 - 0.068 13.5 0.7 1.5 9.2 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF496 PF04363.12 EGC36940.1 - 0.079 13.0 0.2 0.079 13.0 0.2 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF496) TPR_6 PF13174.6 EGC36940.1 - 0.13 12.9 0.0 41 5.1 0.0 4.2 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC36940.1 - 3.8 8.0 7.7 61 4.2 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat Stealth_CR2 PF11380.8 EGC36941.1 - 5.6e-41 139.1 2.0 1.4e-40 137.8 1.7 1.9 2 0 0 2 2 2 1 Stealth protein CR2, conserved region 2 Stealth_CR1 PF17101.5 EGC36941.1 - 1.4e-12 47.0 0.1 3.2e-12 46.0 0.1 1.6 1 0 0 1 1 1 1 Stealth protein CR1, conserved region 1 Stealth_CR4 PF17103.5 EGC36941.1 - 2.8e-12 46.3 0.8 6.5e-12 45.2 0.1 2.1 2 0 0 2 2 2 1 Stealth protein CR4, conserved region 4 Stealth_CR3 PF17102.5 EGC36941.1 - 1e-11 44.6 2.1 1.1e-11 44.4 0.3 2.1 2 0 0 2 2 2 1 Stealth protein CR3, conserved region 3 DUF4413 PF14372.6 EGC36941.1 - 0.095 13.1 0.8 0.4 11.1 0.8 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4413) NUC194 PF08163.12 EGC36942.1 - 7.3e-68 229.3 10.8 7.3e-68 229.3 10.8 4.7 6 1 0 6 6 6 1 NUC194 domain PI3_PI4_kinase PF00454.27 EGC36942.1 - 1.2e-55 189.0 7.4 4.7e-55 187.1 0.1 3.7 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGC36942.1 - 2e-16 60.1 10.2 1e-15 57.9 10.2 2.3 1 0 0 1 1 1 1 FAT domain FATC PF02260.20 EGC36942.1 - 1.2e-10 41.0 1.0 3.7e-10 39.4 0.2 2.2 2 0 0 2 2 2 1 FATC domain MafB19-deam PF14437.6 EGC36942.1 - 0.0066 16.2 0.0 0.024 14.4 0.0 1.9 1 0 0 1 1 1 1 MafB19-like deaminase STAG PF08514.11 EGC36942.1 - 0.46 10.4 8.6 6.6 6.7 0.1 5.0 4 0 0 4 4 4 0 STAG domain Peptidase_C1 PF00112.23 EGC36943.1 - 6e-64 216.1 0.2 7.8e-64 215.7 0.2 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC36943.1 - 1.9e-10 41.0 7.7 1.9e-10 41.0 7.7 2.1 2 1 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C39_2 PF13529.6 EGC36943.1 - 0.015 15.8 0.1 0.039 14.5 0.1 1.7 1 0 0 1 1 1 0 Peptidase_C39 like family DHO_dh PF01180.21 EGC36944.1 - 2.7e-18 66.2 0.1 3.9e-16 59.1 0.3 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.17 EGC36944.1 - 1.2e-06 27.9 0.2 0.0018 17.4 0.1 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) p450 PF00067.22 EGC36945.1 - 5.3e-95 318.9 0.0 6.1e-95 318.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dicty_spore_N PF04562.12 EGC36946.1 - 7.2e-13 49.2 21.3 7.2e-13 49.2 21.3 4.9 3 2 1 4 4 4 2 Dictyostelium spore coat protein, N terminus Pkinase PF00069.25 EGC36947.1 - 7.9e-36 123.8 4.2 1.5e-35 122.8 4.2 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC36947.1 - 1.1e-19 70.8 0.3 1.9e-19 70.0 0.3 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC36947.1 - 5.4e-07 28.7 0.1 8.7e-07 28.1 0.1 1.3 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC36947.1 - 0.00021 20.7 2.3 0.00096 18.6 0.4 2.1 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC36947.1 - 0.00046 20.2 0.4 0.0011 18.9 0.4 1.6 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.22 EGC36947.1 - 0.0086 15.7 0.3 0.016 14.8 0.3 1.4 1 0 0 1 1 1 1 RIO1 family FTA2 PF13095.6 EGC36947.1 - 0.022 14.4 0.2 0.17 11.5 0.1 2.1 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 SLBP_RNA_bind PF15247.6 EGC36948.1 - 3.7e-31 107.0 3.1 1.6e-30 105.0 3.1 2.2 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain RCC1 PF00415.18 EGC36949.1 - 4.6e-79 260.9 13.6 2.2e-13 50.6 0.1 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC36949.1 - 1.6e-37 126.6 33.4 4e-07 29.7 0.9 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGC36949.1 - 1.1e-23 83.6 6.4 9.3e-14 51.6 0.9 3.3 3 0 0 3 3 3 2 BTB/POZ domain Hira PF07569.11 EGC36949.1 - 0.0029 17.4 0.2 0.79 9.4 0.0 3.6 4 0 0 4 4 4 1 TUP1-like enhancer of split DUF3342 PF11822.8 EGC36949.1 - 0.015 15.5 0.6 0.1 12.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3342) Adap_comp_sub PF00928.21 EGC36950.1 - 7.7e-60 202.5 8.8 1.1e-59 202.0 8.8 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGC36950.1 - 1.4e-06 28.2 1.7 2.7e-06 27.4 1.7 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PHAT PF09246.10 EGC36950.1 - 0.015 15.1 0.0 0.031 14.1 0.0 1.5 1 0 0 1 1 1 0 PHAT Porin_3 PF01459.22 EGC36951.1 - 1e-26 94.0 1.7 1.2e-26 93.8 1.7 1.0 1 0 0 1 1 1 1 Eukaryotic porin ParA PF10609.9 EGC36952.1 - 4.6e-100 334.1 0.0 5.1e-100 334.0 0.0 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGC36952.1 - 1e-11 45.0 0.0 5.1e-11 42.7 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGC36952.1 - 5e-10 39.6 0.4 2.7e-09 37.2 0.4 1.9 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGC36952.1 - 1.5e-08 34.2 1.6 1.6e-07 30.8 0.2 2.4 2 1 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.11 EGC36952.1 - 2.9e-07 30.1 0.0 6.2e-07 29.0 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ MeaB PF03308.16 EGC36952.1 - 0.0003 19.9 0.1 0.00044 19.3 0.1 1.2 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB CBP_BcsQ PF06564.12 EGC36952.1 - 0.00072 19.1 0.0 0.0047 16.4 0.0 1.9 1 1 0 1 1 1 1 Cellulose biosynthesis protein BcsQ SRP54 PF00448.22 EGC36952.1 - 0.0015 18.2 0.1 0.023 14.4 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.18 EGC36952.1 - 0.0016 17.9 0.0 0.0059 16.1 0.1 1.8 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.6 EGC36952.1 - 0.0025 17.4 0.0 0.004 16.7 0.0 1.3 1 0 0 1 1 1 1 AAA domain CLP1_P PF16575.5 EGC36952.1 - 0.0039 17.0 0.1 0.0076 16.1 0.0 1.5 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop APS_kinase PF01583.20 EGC36952.1 - 0.0063 16.4 0.0 0.0089 15.9 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Zeta_toxin PF06414.12 EGC36952.1 - 0.0073 15.6 0.0 0.01 15.1 0.0 1.2 1 0 0 1 1 1 1 Zeta toxin AAA_26 PF13500.6 EGC36952.1 - 0.015 15.1 0.6 2.9 7.7 0.4 2.2 2 0 0 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGC36952.1 - 0.025 14.5 1.1 0.041 13.8 0.5 1.7 2 0 0 2 2 1 0 RsgA GTPase NB-ARC PF00931.22 EGC36952.1 - 0.047 12.9 0.2 0.075 12.2 0.2 1.3 1 0 0 1 1 1 0 NB-ARC domain KTI12 PF08433.10 EGC36952.1 - 0.09 12.2 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 Rad17 PF03215.15 EGC36952.1 - 0.11 12.4 0.2 0.46 10.4 0.1 1.9 2 0 0 2 2 2 0 Rad17 P-loop domain RNA_helicase PF00910.22 EGC36952.1 - 0.12 12.8 0.6 0.89 10.0 0.2 2.2 1 1 1 2 2 2 0 RNA helicase MMR_HSR1 PF01926.23 EGC36952.1 - 0.15 12.1 0.8 20 5.3 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase Usp PF00582.26 EGC36953.1 - 6e-16 59.2 0.0 1.5e-09 38.5 0.0 2.0 1 1 0 2 2 2 2 Universal stress protein family AAA PF00004.29 EGC36954.1 - 1.4e-54 184.1 0.0 1.9e-32 112.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC36954.1 - 5.2e-19 67.8 0.0 8.4e-09 35.1 0.0 2.5 2 0 0 2 2 2 2 AAA+ lid domain AAA_16 PF13191.6 EGC36954.1 - 1.9e-11 44.6 0.0 0.021 15.2 0.0 4.2 2 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.14 EGC36954.1 - 6e-08 32.8 0.0 0.0073 16.3 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) ABC_tran PF00005.27 EGC36954.1 - 1.4e-06 28.9 0.0 0.083 13.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter TIP49 PF06068.13 EGC36954.1 - 2.1e-06 27.2 0.0 0.025 13.8 0.0 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain RNA_helicase PF00910.22 EGC36954.1 - 1.7e-05 25.2 0.0 0.28 11.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase DUF815 PF05673.13 EGC36954.1 - 1.7e-05 24.1 0.0 0.092 11.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.12 EGC36954.1 - 2.2e-05 24.4 0.3 0.049 13.6 0.0 3.7 2 2 2 4 4 4 1 NACHT domain AAA_7 PF12775.7 EGC36954.1 - 2.4e-05 23.9 0.0 0.041 13.4 0.0 2.4 2 0 0 2 2 2 2 P-loop containing dynein motor region Sigma54_activat PF00158.26 EGC36954.1 - 2.8e-05 23.9 0.0 0.12 12.0 0.0 2.9 2 1 1 3 3 3 2 Sigma-54 interaction domain RuvB_N PF05496.12 EGC36954.1 - 4.2e-05 23.4 0.0 0.0064 16.2 0.0 3.1 2 1 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC36954.1 - 4.2e-05 23.8 0.1 0.66 10.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGC36954.1 - 6.3e-05 23.0 0.1 0.31 11.1 0.1 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.21 EGC36954.1 - 9.2e-05 21.9 0.0 0.0059 16.0 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Parvo_NS1 PF01057.17 EGC36954.1 - 0.00029 20.0 0.1 0.02 14.0 0.0 2.5 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 NB-ARC PF00931.22 EGC36954.1 - 0.00056 19.2 0.0 0.29 10.3 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.6 EGC36954.1 - 0.00065 19.4 0.0 1.3 8.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_33 PF13671.6 EGC36954.1 - 0.00076 19.7 0.0 0.67 10.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGC36954.1 - 0.00089 19.2 2.7 0.068 13.1 0.1 3.0 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea TniB PF05621.11 EGC36954.1 - 0.0016 17.9 0.1 0.86 9.0 0.0 3.2 2 1 1 3 3 3 1 Bacterial TniB protein IstB_IS21 PF01695.17 EGC36954.1 - 0.0018 18.0 0.0 0.083 12.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein Sigma54_activ_2 PF14532.6 EGC36954.1 - 0.0023 18.1 0.0 0.13 12.4 0.0 2.8 2 0 0 2 2 2 1 Sigma-54 interaction domain Zeta_toxin PF06414.12 EGC36954.1 - 0.0057 16.0 0.0 2.5 7.4 0.0 2.5 3 0 0 3 3 2 1 Zeta toxin Bac_DnaA PF00308.18 EGC36954.1 - 0.0062 16.4 0.0 0.27 11.1 0.0 2.6 2 0 0 2 2 2 1 Bacterial dnaA protein AAA_24 PF13479.6 EGC36954.1 - 0.0086 15.8 0.0 2.2 7.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGC36954.1 - 0.015 15.2 0.0 0.15 11.9 0.0 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_18 PF13238.6 EGC36954.1 - 0.018 15.6 0.1 0.53 10.8 0.0 3.1 3 0 0 3 3 2 0 AAA domain TsaE PF02367.17 EGC36954.1 - 0.022 14.7 0.0 10 6.2 0.0 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATPase PF06745.13 EGC36954.1 - 0.028 13.8 1.1 1.4 8.2 0.0 3.0 2 1 1 3 3 3 0 KaiC Rad17 PF03215.15 EGC36954.1 - 0.03 14.3 4.4 0.43 10.5 0.2 3.5 3 1 1 4 4 4 0 Rad17 P-loop domain Guanylate_kin PF00625.21 EGC36954.1 - 0.046 13.4 1.2 18 4.9 0.0 3.6 3 0 0 3 3 3 0 Guanylate kinase Fe-S_assembly PF04384.13 EGC36954.1 - 0.078 13.6 0.0 7.9 7.2 0.0 3.5 2 1 1 3 3 3 0 Iron-sulphur cluster assembly NTPase_1 PF03266.15 EGC36954.1 - 0.095 12.6 0.0 1.8 8.4 0.1 2.5 2 0 0 2 2 2 0 NTPase DUF2075 PF09848.9 EGC36954.1 - 0.12 11.6 0.0 6.2 6.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) MMR_HSR1 PF01926.23 EGC36954.1 - 0.26 11.4 2.6 6.3 6.9 0.5 3.2 3 1 0 3 3 3 0 50S ribosome-binding GTPase 2-Hacid_dh_C PF02826.19 EGC36955.1 - 1.2e-49 168.1 0.0 1.7e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC36955.1 - 8.7e-32 109.6 0.0 1e-31 109.4 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC36955.1 - 8.5e-06 26.0 0.0 1.8e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.22 EGC36955.1 - 0.0036 18.1 0.1 5.6 7.8 0.0 2.5 2 1 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.24 EGC36955.1 - 0.037 14.5 0.1 5.4 7.5 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain GT-D PF08759.11 EGC36955.1 - 0.061 13.0 0.5 0.82 9.3 0.0 2.4 2 1 0 2 2 2 0 Glycosyltransferase GT-D fold BBS2_N PF14781.6 EGC36955.1 - 0.13 12.1 0.8 0.76 9.7 0.0 2.6 3 1 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal CPSase_L_D2 PF02786.17 EGC36956.1 - 2.3e-113 376.9 0.2 2.1e-84 282.3 0.1 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.22 EGC36956.1 - 1.3e-50 170.5 0.0 5.8e-50 168.4 0.0 2.2 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.21 EGC36956.1 - 5.8e-47 159.4 0.0 1.4e-46 158.2 0.0 1.7 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain GATase PF00117.28 EGC36956.1 - 2.6e-42 144.8 0.0 6.8e-42 143.4 0.0 1.8 2 0 0 2 2 2 1 Glutamine amidotransferase class-I CPSase_L_D3 PF02787.19 EGC36956.1 - 1.5e-39 135.1 0.5 6.2e-39 133.1 0.1 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain OTCace PF00185.24 EGC36956.1 - 2.7e-34 118.5 0.1 1e-33 116.6 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain Dala_Dala_lig_C PF07478.13 EGC36956.1 - 7.1e-22 77.9 1.7 3.9e-11 42.9 0.2 2.5 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.22 EGC36956.1 - 6.2e-19 68.0 0.0 9.5e-18 64.2 0.0 3.0 3 0 0 3 3 2 1 MGS-like domain ATP-grasp PF02222.22 EGC36956.1 - 1.8e-17 63.5 0.2 2.9e-10 40.0 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain Amidohydro_1 PF01979.20 EGC36956.1 - 4.5e-12 45.9 0.0 4.4e-11 42.7 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase family ATPgrasp_Ter PF15632.6 EGC36956.1 - 2e-11 43.8 0.0 1.9e-05 24.4 0.0 2.8 2 0 0 2 2 2 2 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_3 PF02655.14 EGC36956.1 - 2.2e-10 40.8 0.7 8.3e-05 22.7 0.1 2.6 2 0 0 2 2 2 2 ATP-grasp domain Peptidase_C26 PF07722.13 EGC36956.1 - 0.062 13.0 0.8 2.9 7.6 0.8 2.6 1 1 0 1 1 1 0 Peptidase C26 TPP_enzyme_M PF00205.22 EGC36956.1 - 0.14 11.9 0.0 11 5.8 0.0 3.1 3 0 0 3 3 3 0 Thiamine pyrophosphate enzyme, central domain EF-hand_6 PF13405.6 EGC36957.1 - 8.8e-17 59.5 8.6 2.3e-05 24.0 0.1 4.2 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.6 EGC36957.1 - 8e-16 58.3 3.4 8e-08 32.6 0.8 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC36957.1 - 7.6e-14 50.2 9.2 0.00012 21.4 0.0 3.8 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGC36957.1 - 1.4e-12 47.2 3.8 6.2e-05 22.8 0.1 3.7 2 2 2 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC36957.1 - 2.5e-11 42.5 3.2 0.00012 21.4 0.0 3.1 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.9 EGC36957.1 - 3.2e-06 27.4 3.0 0.0019 18.5 1.1 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region PqqD PF05402.12 EGC36957.1 - 0.004 17.4 0.3 0.21 11.9 0.1 2.7 3 0 0 3 3 3 1 Coenzyme PQQ synthesis protein D (PqqD) DUF2624 PF11116.8 EGC36957.1 - 0.0047 17.8 0.6 1.4 9.9 0.3 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF2624) MICSWaP PF17018.5 EGC36957.1 - 0.0053 16.3 0.1 0.33 10.5 0.1 2.2 2 0 0 2 2 2 1 Spore wall protein EF-hand_10 PF14788.6 EGC36957.1 - 0.0089 15.9 0.7 2 8.3 0.1 2.9 3 0 0 3 3 3 1 EF hand DUF1186 PF06685.11 EGC36957.1 - 0.021 14.2 0.3 0.13 11.6 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1186) EF-hand_4 PF12763.7 EGC36957.1 - 0.037 14.0 0.7 0.14 12.1 0.0 2.0 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand Na_Ca_ex_C PF16494.5 EGC36957.1 - 0.053 14.0 0.3 0.29 11.6 0.2 2.0 1 1 0 1 1 1 0 C-terminal extension of sodium/calcium exchanger domain HJURP_C PF12347.8 EGC36958.1 - 2 8.5 7.0 1.5 8.9 1.7 3.2 3 0 0 3 3 3 0 Holliday junction regulator protein family C-terminal repeat Sensor_TM1 PF13755.6 EGC36959.1 - 0.089 12.5 0.4 0.21 11.3 0.4 1.5 1 0 0 1 1 1 0 Sensor N-terminal transmembrane domain MAP17 PF15807.5 EGC36961.1 - 0.00027 21.1 1.2 0.00027 21.1 1.2 3.2 2 1 1 3 3 3 1 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4834 PF16118.5 EGC36961.1 - 0.00033 21.6 9.6 0.00033 21.6 9.6 4.1 1 1 2 3 3 2 1 Domain of unknown function (DUF4834) OSTbeta PF15048.6 EGC36961.1 - 0.0014 18.8 1.9 0.0014 18.8 1.9 2.1 2 1 0 2 2 2 1 Organic solute transporter subunit beta protein Connexin PF00029.19 EGC36961.1 - 0.013 15.2 1.2 0.013 15.2 1.2 2.3 1 1 0 2 2 2 0 Connexin WcbI PF18588.1 EGC36961.1 - 0.039 13.6 0.3 0.078 12.6 0.3 1.5 1 1 0 1 1 1 0 Polysaccharide biosynthesis enzyme WcbI TFIIA PF03153.13 EGC36961.1 - 0.086 12.8 37.1 0.11 12.5 37.1 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FAM176 PF14851.6 EGC36961.1 - 0.14 11.8 0.1 0.14 11.8 0.1 2.3 2 1 0 2 2 2 0 FAM176 family Folate_carrier PF01770.18 EGC36961.1 - 0.19 10.4 3.3 0.41 9.3 3.3 1.6 1 0 0 1 1 1 0 Reduced folate carrier DUF2448 PF10476.9 EGC36961.1 - 0.19 11.5 0.3 0.32 10.8 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function C-terminus (DUF2448) OAD_gamma PF04277.13 EGC36961.1 - 0.21 12.2 0.0 0.57 10.8 0.0 1.8 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain BT1 PF03092.16 EGC36961.1 - 1.9 6.6 3.9 2.4 6.3 3.9 1.1 1 0 0 1 1 1 0 BT1 family DUF4634 PF15465.6 EGC36962.1 - 4.1 7.7 6.9 6.8 7.0 5.3 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) Ras PF00071.22 EGC36963.1 - 6.6e-51 172.1 0.1 1.4e-36 125.6 0.0 2.7 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGC36963.1 - 6.3e-19 68.4 0.0 5.9e-10 39.4 0.0 2.8 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGC36963.1 - 1.2e-07 31.7 0.0 3.1e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 RsgA GTPase Arf PF00025.21 EGC36963.1 - 2.6e-07 30.3 0.4 0.00024 20.6 0.0 3.2 3 1 1 4 4 4 2 ADP-ribosylation factor family Sec23_trunk PF04811.15 EGC36963.1 - 1.3e-05 24.9 0.2 0.0005 19.7 0.2 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain GTP_EFTU PF00009.27 EGC36963.1 - 9.8e-05 22.0 0.1 0.00025 20.7 0.1 1.7 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain zf-Sec23_Sec24 PF04810.15 EGC36963.1 - 0.00011 22.1 6.4 0.00025 21.0 6.4 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger FeoB_N PF02421.18 EGC36963.1 - 0.00087 18.9 0.1 0.02 14.5 0.0 3.0 3 0 0 3 3 3 1 Ferrous iron transport protein B VWA_2 PF13519.6 EGC36963.1 - 0.0011 19.6 0.0 0.17 12.6 0.0 3.1 1 1 1 2 2 2 1 von Willebrand factor type A domain MMR_HSR1 PF01926.23 EGC36963.1 - 0.0079 16.3 0.0 8.1 6.6 0.0 3.3 3 0 0 3 3 3 1 50S ribosome-binding GTPase Sec23_BS PF08033.12 EGC36963.1 - 0.008 16.9 1.5 0.027 15.2 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain TniB PF05621.11 EGC36963.1 - 0.029 13.8 0.0 0.069 12.5 0.0 1.6 1 0 0 1 1 1 0 Bacterial TniB protein Herpes_UL31 PF02718.14 EGC36963.1 - 0.031 13.2 0.1 0.078 11.9 0.1 1.7 1 0 0 1 1 1 0 Herpesvirus UL31-like protein VWA PF00092.28 EGC36963.1 - 0.88 9.8 3.9 5 7.4 2.4 3.0 2 1 0 2 2 2 0 von Willebrand factor type A domain Dus PF01207.17 EGC36964.1 - 4.4e-46 157.4 0.0 1.1e-45 156.1 0.0 1.6 1 1 1 2 2 2 1 Dihydrouridine synthase (Dus) Myosin-VI_CBD PF16521.5 EGC36964.1 - 0.12 12.4 0.0 0.29 11.2 0.0 1.7 1 0 0 1 1 1 0 Myosin VI cargo binding domain Ank_4 PF13637.6 EGC36965.1 - 7.2e-07 29.6 0.1 2.6e-05 24.7 0.0 2.8 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC36965.1 - 2.2e-06 27.8 0.0 1.1e-05 25.5 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC36965.1 - 1e-05 26.0 0.3 4.2e-05 24.1 0.3 2.1 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC36965.1 - 1.6e-05 24.9 0.1 0.00088 19.6 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.30 EGC36965.1 - 0.0013 19.1 0.5 0.064 13.7 0.1 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF2096 PF09869.9 EGC36965.1 - 0.015 15.4 0.3 0.048 13.7 0.3 1.8 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2096) Rsbr_N PF08678.10 EGC36965.1 - 0.018 15.1 2.2 0.13 12.4 0.1 2.6 3 0 0 3 3 3 0 Rsbr N terminal Mgm101p PF06420.12 EGC36966.1 - 1.1e-72 243.0 0.0 1.8e-72 242.4 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF966 PF06136.13 EGC36967.1 - 4.8 6.8 18.6 7.1 6.2 18.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) PPP4R2 PF09184.11 EGC36967.1 - 4.9 6.7 7.7 8.8 5.8 7.7 1.5 1 0 0 1 1 1 0 PPP4R2 Apt1 PF10351.9 EGC36967.1 - 5.7 5.7 11.7 8.5 5.1 11.7 1.3 1 0 0 1 1 1 0 Golgi-body localisation protein domain Hamartin PF04388.12 EGC36967.1 - 8.6 4.9 29.7 11 4.5 29.7 1.1 1 0 0 1 1 1 0 Hamartin protein LSM PF01423.22 EGC36968.1 - 3.3e-20 71.5 1.0 4.5e-20 71.1 1.0 1.2 1 0 0 1 1 1 1 LSM domain HydF_dimer PF18128.1 EGC36968.1 - 0.044 13.8 0.3 0.1 12.7 0.2 1.6 1 1 0 2 2 2 0 Hydrogen maturase F dimerization domain Pex16 PF08610.10 EGC36969.1 - 3.4e-52 177.6 0.0 6.6e-52 176.7 0.0 1.4 1 1 0 1 1 1 1 Peroxisomal membrane protein (Pex16) Menin PF05053.13 EGC36969.1 - 0.06 11.7 0.1 0.08 11.3 0.1 1.1 1 0 0 1 1 1 0 Menin DUF5644 PF18712.1 EGC36969.1 - 0.068 13.2 0.8 0.22 11.6 0.8 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5644) Mucin PF01456.17 EGC36970.1 - 0.7 9.9 13.2 1.3 9.0 13.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.8 EGC36970.1 - 1.9 8.5 9.5 5.2 7.0 7.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DDE_Tnp_1_7 PF13843.6 EGC36971.1 - 5e-13 49.1 0.0 7.2e-13 48.6 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 DDE_Tnp_4 PF13359.6 EGC36972.1 - 1.5e-08 34.4 0.0 2.1e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease FNIP PF05725.12 EGC36976.1 - 1e-60 201.6 75.4 2.6e-10 40.3 2.0 7.0 1 1 10 11 11 11 11 FNIP Repeat LRR_5 PF13306.6 EGC36976.1 - 7.2e-06 26.0 3.1 0.0012 18.8 1.5 3.2 2 1 1 3 3 3 1 BspA type Leucine rich repeat region (6 copies) Lipoprotein_17 PF04200.12 EGC36976.1 - 0.32 11.4 9.4 3.2 8.2 0.1 3.5 2 1 2 5 5 5 0 Lipoprotein associated domain DUF1939 PF09154.10 EGC36977.1 - 2.3 8.4 6.0 18 5.6 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1939) MafB PF06255.13 EGC36977.1 - 3.3 7.1 7.4 9.5 5.6 2.5 2.8 1 1 1 2 2 2 0 Neisseria toxin MafB GATA PF00320.27 EGC36978.1 - 1.4e-09 37.4 2.9 5e-09 35.6 2.9 1.9 1 1 0 1 1 1 1 GATA zinc finger CAV_VP3 PF04771.12 EGC36978.1 - 0.028 14.6 0.2 0.053 13.7 0.2 1.4 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein zf-CCCH_6 PF18585.1 EGC36979.1 - 0.73 9.8 2.2 4.5 7.2 0.1 2.5 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 Herpes_UL92 PF03048.14 EGC36979.1 - 1.6 8.5 6.0 1.2 8.8 0.8 2.3 2 0 0 2 2 2 0 UL92 family GATA PF00320.27 EGC36980.1 - 7e-06 25.6 8.2 1.2e-05 24.7 8.2 1.4 1 0 0 1 1 1 1 GATA zinc finger Homeodomain PF00046.29 EGC36981.1 - 1.5e-13 50.4 1.7 4.9e-07 29.5 0.1 2.9 2 0 0 2 2 2 2 Homeodomain Homeobox_KN PF05920.11 EGC36981.1 - 4.4e-07 29.7 0.2 0.0011 18.8 0.0 2.9 2 0 0 2 2 2 2 Homeobox KN domain GATA PF00320.27 EGC36982.1 - 1.9e-07 30.6 6.8 2.8e-07 30.0 6.8 1.3 1 0 0 1 1 1 1 GATA zinc finger OSTMP1 PF09777.9 EGC36982.1 - 0.24 10.8 3.3 0.38 10.1 3.4 1.5 1 1 0 1 1 1 0 Osteopetrosis-associated transmembrane protein 1 precursor Hid1 PF12722.7 EGC36985.1 - 0.015 13.4 21.7 0.02 13.0 21.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein BUD22 PF09073.10 EGC36985.1 - 0.086 12.2 36.4 0.12 11.7 36.4 1.1 1 0 0 1 1 1 0 BUD22 CDC45 PF02724.14 EGC36985.1 - 0.17 10.1 23.5 0.23 9.7 23.5 1.1 1 0 0 1 1 1 0 CDC45-like protein LAP1C PF05609.12 EGC36985.1 - 0.29 10.2 25.8 0.43 9.6 25.8 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Plasmod_Pvs28 PF06247.11 EGC36985.1 - 0.43 10.9 8.3 6.8 7.1 6.2 3.3 3 0 0 3 3 2 0 Pvs28 EGF domain SLC12 PF03522.15 EGC36985.1 - 0.53 9.2 18.1 0.82 8.6 18.1 1.2 1 0 0 1 1 1 0 Solute carrier family 12 GREB1 PF15782.5 EGC36985.1 - 0.62 7.1 27.9 0.81 6.7 27.9 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EGC36985.1 - 1.1 8.4 29.9 1.7 7.8 29.9 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein SPX PF03105.19 EGC36985.1 - 1.3 8.8 30.6 2 8.3 30.6 1.2 1 0 0 1 1 1 0 SPX domain DUF1387 PF07139.11 EGC36985.1 - 1.8 8.2 28.3 2.8 7.6 28.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1387) Macoilin PF09726.9 EGC36985.1 - 2 6.9 29.3 2.7 6.4 29.3 1.1 1 0 0 1 1 1 0 Macoilin family Hamartin PF04388.12 EGC36985.1 - 2.8 6.5 23.3 3.8 6.1 23.3 1.1 1 0 0 1 1 1 0 Hamartin protein SOBP PF15279.6 EGC36985.1 - 6.9 7.2 21.8 11 6.5 21.8 1.2 1 0 0 1 1 1 0 Sine oculis-binding protein Frankia_peptide PF14407.6 EGC36986.1 - 0.16 12.0 1.3 12 5.9 0.0 2.6 1 1 1 2 2 2 0 Ribosomally synthesized peptide prototyped by Frankia Franean1_4349. TFIIA PF03153.13 EGC36986.1 - 7.6 6.4 20.2 7.9 6.4 20.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit P5-ATPase PF12409.8 EGC36986.1 - 8.1 6.6 8.2 2.3 8.3 4.8 1.7 1 1 1 2 2 2 0 P5-type ATPase cation transporter DDE_Tnp_4 PF13359.6 EGC36988.1 - 1.4e-09 37.8 0.2 1.8e-09 37.5 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease PDU_like PF15953.5 EGC36988.1 - 0.012 15.7 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 0 Putative propanediol utilisation FNIP PF05725.12 EGC36991.1 - 2.5e-37 126.8 49.0 7.8e-12 45.2 2.5 9.2 6 2 5 11 11 11 8 FNIP Repeat Get5_bdg PF16843.5 EGC36991.1 - 0.097 12.2 0.4 2 8.0 0.0 3.1 3 0 0 3 3 3 0 Binding domain to Get4 on Get5, Golgi to ER traffic protein D123 PF07065.14 EGC36992.1 - 0.0032 16.7 5.0 0.0039 16.4 5.0 1.1 1 0 0 1 1 1 1 D123 CLN3 PF02487.17 EGC36992.1 - 0.043 12.9 1.1 0.049 12.7 1.1 1.1 1 0 0 1 1 1 0 CLN3 protein Conotoxin PF02950.17 EGC36992.1 - 0.048 14.7 0.4 0.091 13.8 0.4 1.5 1 0 0 1 1 1 0 Conotoxin CPSF100_C PF13299.6 EGC36992.1 - 0.053 13.7 0.6 0.059 13.5 0.6 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF3086 PF11285.8 EGC36992.1 - 0.067 12.3 3.7 0.084 12.0 2.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Folate_carrier PF01770.18 EGC36992.1 - 0.11 11.2 1.3 0.13 11.0 1.3 1.1 1 0 0 1 1 1 0 Reduced folate carrier SCAI PF12070.8 EGC36992.1 - 0.24 10.2 7.0 0.27 10.1 7.0 1.0 1 0 0 1 1 1 0 Protein SCAI Presenilin PF01080.17 EGC36992.1 - 0.25 10.1 6.3 0.29 9.9 6.3 1.1 1 0 0 1 1 1 0 Presenilin O-antigen_lig PF13425.6 EGC36992.1 - 0.33 9.7 10.9 0.38 9.5 10.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein ALMT PF11744.8 EGC36992.1 - 0.96 8.2 8.7 1 8.1 8.7 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Gti1_Pac2 PF09729.9 EGC36992.1 - 1.5 8.9 10.8 1.8 8.6 10.8 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family EVI2A PF05399.11 EGC36992.1 - 1.7 8.2 16.6 2.1 7.9 16.6 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) PDDEXK_6 PF04720.12 EGC36992.1 - 2.2 8.1 5.0 2.6 7.9 5.0 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function Med21 PF11221.8 EGC36992.1 - 2.3 8.4 5.3 3.2 8.0 5.3 1.2 1 0 0 1 1 1 0 Subunit 21 of Mediator complex Connexin PF00029.19 EGC36992.1 - 2.6 7.7 3.9 1.7 8.4 2.6 1.4 1 1 0 1 1 1 0 Connexin GCD14 PF08704.10 EGC36992.1 - 4.9 6.7 5.8 5.6 6.6 5.8 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit MMU163 PF17119.5 EGC36992.1 - 5.7 6.0 8.4 7.3 5.7 8.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein up-regulated during meiosis FlaG PF03646.15 EGC36992.1 - 6.7 6.9 16.7 10 6.4 16.7 1.3 1 0 0 1 1 1 0 FlaG protein NOA36 PF06524.12 EGC36992.1 - 7.2 5.8 8.2 9 5.5 8.2 1.1 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.12 EGC36993.1 - 0.87 8.9 36.9 1 8.7 36.9 1.1 1 0 0 1 1 1 0 SDA1 Nop14 PF04147.12 EGC36993.1 - 0.92 7.6 33.5 1.2 7.3 33.5 1.3 1 0 0 1 1 1 0 Nop14-like family Trans_reg_C PF00486.28 EGC36995.1 - 0.0048 17.0 0.5 0.013 15.5 0.5 1.7 1 0 0 1 1 1 1 Transcriptional regulatory protein, C terminal TIG PF01833.24 EGC36996.1 - 2.1e-12 46.9 33.6 2.2e-05 24.4 3.0 5.5 4 1 1 5 5 5 4 IPT/TIG domain TBP-binding PF09247.11 EGC36996.1 - 0.08 13.2 1.9 0.12 12.6 0.5 1.9 2 0 0 2 2 2 0 TATA box-binding protein binding CARDB PF07705.11 EGC36996.1 - 2.3 8.5 10.0 0.079 13.2 1.0 3.2 3 1 0 3 3 3 0 CARDB TIG PF01833.24 EGC36997.1 - 1.2e-14 54.1 31.9 3e-06 27.2 2.6 5.5 6 0 0 6 6 6 4 IPT/TIG domain TBP-binding PF09247.11 EGC36997.1 - 0.037 14.3 0.5 0.11 12.8 0.5 1.7 1 0 0 1 1 1 0 TATA box-binding protein binding CARDB PF07705.11 EGC36997.1 - 2.1 8.7 9.1 0.097 12.9 1.4 2.8 3 0 0 3 3 3 0 CARDB TIG PF01833.24 EGC36998.1 - 1.8e-11 44.0 43.8 2.7e-06 27.4 2.7 6.9 7 0 0 7 7 7 4 IPT/TIG domain TBP-binding PF09247.11 EGC36998.1 - 0.41 10.9 4.2 0.16 12.2 0.5 2.1 2 0 0 2 2 2 0 TATA box-binding protein binding TIG PF01833.24 EGC36999.1 - 5e-08 32.9 39.4 2.7e-06 27.4 2.7 7.4 8 1 0 9 9 9 4 IPT/TIG domain Tudor_2 PF18104.1 EGC36999.1 - 0.04 13.6 0.1 15 5.3 0.0 3.1 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TBP-binding PF09247.11 EGC36999.1 - 1.1 9.6 3.4 0.65 10.3 0.3 2.1 2 0 0 2 2 2 0 TATA box-binding protein binding TIG PF01833.24 EGC37000.1 - 1.3e-11 44.4 26.8 1.5e-06 28.2 1.1 5.2 4 1 1 5 5 5 4 IPT/TIG domain Tudor_2 PF18104.1 EGC37000.1 - 0.089 12.5 0.1 0.49 10.1 0.0 2.3 2 0 0 2 2 2 0 Jumonji domain-containing protein 2A Tudor domain TBP-binding PF09247.11 EGC37000.1 - 0.36 11.1 1.8 0.92 9.8 0.5 2.2 2 0 0 2 2 2 0 TATA box-binding protein binding Vma12 PF11712.8 EGC37001.1 - 0.15 12.1 0.1 0.23 11.5 0.1 1.2 1 0 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Atg14 PF10186.9 EGC37003.1 - 0.55 9.3 19.4 17 4.3 19.4 2.1 1 1 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 NADH_B2 PF14813.6 EGC37004.1 - 0.1 12.4 0.8 0.28 11.0 0.8 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 GATA PF00320.27 EGC37005.1 - 0.036 13.7 0.8 0.27 10.9 0.0 2.4 2 0 0 2 2 2 0 GATA zinc finger bZIP_1 PF00170.21 EGC37008.1 - 3.9e-07 30.1 9.7 3.9e-07 30.1 9.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor TFIIA PF03153.13 EGC37008.1 - 2.5e-05 24.5 30.1 3.5e-05 24.0 17.3 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit bZIP_2 PF07716.15 EGC37008.1 - 0.00016 21.7 14.2 0.00016 21.7 14.2 2.5 2 0 0 2 2 2 1 Basic region leucine zipper DivIC PF04977.15 EGC37008.1 - 0.14 12.0 0.2 0.14 12.0 0.2 4.1 4 2 0 4 4 4 0 Septum formation initiator CRM1_C PF08767.11 EGC37009.1 - 2.9e-114 381.5 11.2 2.9e-114 381.5 11.2 3.4 3 1 0 3 3 3 1 CRM1 C terminal Xpo1 PF08389.12 EGC37009.1 - 3.7e-33 114.7 5.6 3.7e-33 114.7 5.6 4.8 5 1 0 5 5 5 1 Exportin 1-like protein CRM1_repeat_2 PF18784.1 EGC37009.1 - 4.4e-32 109.5 1.9 1e-31 108.4 1.1 2.2 2 0 0 2 2 2 1 CRM1 / Exportin repeat 2 CRM1_repeat_3 PF18787.1 EGC37009.1 - 5.4e-26 90.5 3.2 2.4e-25 88.4 0.1 3.4 4 0 0 4 4 4 1 CRM1 / Exportin repeat 3 CRM1_repeat PF18777.1 EGC37009.1 - 4.3e-17 61.3 1.3 1e-16 60.1 1.3 1.7 1 0 0 1 1 1 1 Chromosome region maintenance or exportin repeat IBN_N PF03810.19 EGC37009.1 - 3.4e-15 55.7 0.0 1.6e-14 53.6 0.0 2.3 1 0 0 1 1 1 1 Importin-beta N-terminal domain UCH PF00443.29 EGC37009.1 - 0.073 12.6 0.0 0.26 10.7 0.0 2.1 1 1 0 1 1 1 0 Ubiquitin carboxyl-terminal hydrolase V-ATPase_H_C PF11698.8 EGC37009.1 - 0.093 12.8 5.7 0.13 12.4 0.2 3.9 4 0 0 4 4 4 0 V-ATPase subunit H DUF3385 PF11865.8 EGC37009.1 - 0.13 12.2 7.4 0.16 11.9 0.0 4.6 6 2 0 6 6 6 0 Domain of unknown function (DUF3385) Vac14_Fab1_bd PF12755.7 EGC37009.1 - 0.18 12.4 3.3 4.8 7.8 0.0 4.0 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region CAF-1_p150 PF11600.8 EGC37010.1 - 0.0036 17.0 45.4 0.0096 15.6 45.4 1.6 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal CDC45 PF02724.14 EGC37010.1 - 0.027 12.8 24.6 0.05 11.9 24.6 1.4 1 0 0 1 1 1 0 CDC45-like protein TTR-52 PF01060.23 EGC37010.1 - 0.2 12.4 0.1 0.2 12.4 0.1 2.6 3 0 0 3 3 3 0 Transthyretin-like family Draxin PF15550.6 EGC37010.1 - 0.57 10.0 25.0 1.2 8.9 25.0 1.5 1 0 0 1 1 1 0 Draxin DDRGK PF09756.9 EGC37010.1 - 4.9 6.7 37.9 15 5.1 37.9 1.8 1 0 0 1 1 1 0 DDRGK domain Alpha_kinase PF02816.18 EGC37011.1 - 1.6e-60 204.4 0.0 1.6e-60 204.4 0.0 3.1 3 0 0 3 3 3 1 Alpha-kinase family WD40 PF00400.32 EGC37011.1 - 2.7e-32 110.3 22.5 5e-05 24.0 0.0 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37011.1 - 1.3e-06 28.7 0.1 0.0011 19.3 0.0 4.0 2 1 1 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC37011.1 - 0.00055 19.4 4.2 0.0074 15.7 0.3 4.9 4 2 2 6 6 6 2 WD40-like domain PID_2 PF14719.6 EGC37011.1 - 0.01 15.7 3.3 0.013 15.4 0.5 2.5 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) PQQ_3 PF13570.6 EGC37011.1 - 0.088 13.3 0.1 22 5.7 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain DUF2746 PF10874.8 EGC37011.1 - 0.094 13.2 2.0 1.7 9.1 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) BING4CT PF08149.11 EGC37011.1 - 0.12 12.2 1.3 1 9.2 0.1 2.9 2 0 0 2 2 2 0 BING4CT (NUC141) domain Exonuc_VII_L PF02601.15 EGC37011.1 - 6.5 6.2 42.6 0.082 12.5 9.8 3.2 2 1 1 3 3 3 0 Exonuclease VII, large subunit NAGidase PF07555.13 EGC37012.1 - 1.1e-14 54.5 1.8 2.7e-14 53.2 1.8 1.6 1 1 0 1 1 1 1 beta-N-acetylglucosaminidase Myb_DNA-bind_6 PF13921.6 EGC37013.1 - 2.3e-15 56.6 5.3 2e-10 40.7 0.1 2.8 2 1 1 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.31 EGC37013.1 - 1.7e-14 53.7 3.3 1.5e-06 28.3 0.6 2.2 2 0 0 2 2 2 2 Myb-like DNA-binding domain PP-binding PF00550.25 EGC37014.1 - 1.1e-13 51.4 0.1 1.3e-13 51.1 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.6 EGC37014.1 - 0.0014 18.8 0.7 0.0028 17.8 0.7 1.5 1 1 0 1 1 1 1 Acyl-carrier zf-PARP PF00645.18 EGC37015.1 - 5.9e-22 78.3 1.3 5.9e-22 78.3 1.3 2.2 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.9 EGC37015.1 - 1.3e-09 37.8 7.2 3.7e-09 36.4 7.2 1.9 1 0 0 1 1 1 1 PBZ domain FHA_2 PF17913.1 EGC37015.1 - 2.4e-05 24.5 0.0 6.4e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 FHA domain Ubie_methyltran PF01209.18 EGC37016.1 - 2.3e-91 305.2 0.0 2.7e-91 305.0 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGC37016.1 - 1.8e-13 51.0 0.0 5.6e-12 46.2 0.0 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC37016.1 - 2.7e-13 50.4 0.0 1.8e-12 47.8 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC37016.1 - 6.2e-07 29.4 0.0 1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC37016.1 - 2.4e-06 28.2 0.0 8e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37016.1 - 8.8e-06 25.6 0.0 4.3e-05 23.4 0.0 2.2 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGC37016.1 - 0.00085 19.2 0.0 0.0055 16.6 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase DUF1908 PF08926.11 EGC37016.1 - 0.063 12.4 1.2 0.096 11.8 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Redoxin PF08534.10 EGC37017.1 - 2.4e-10 40.3 0.0 3.1e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Redoxin PI3_PI4_kinase PF00454.27 EGC37018.1 - 1.9e-30 106.5 0.3 7.6e-30 104.5 0.0 2.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase SF3a60_bindingd PF12108.8 EGC37018.1 - 4.2 7.3 6.3 7.5 6.5 6.3 1.4 1 0 0 1 1 1 0 Splicing factor SF3a60 binding domain DnaJ PF00226.31 EGC37019.1 - 0.00029 20.9 1.0 0.00029 20.9 1.0 2.9 2 1 1 3 3 3 1 DnaJ domain DUF5617 PF18493.1 EGC37019.1 - 0.025 14.6 4.3 0.075 13.1 3.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF5617) Cas9_a PF18470.1 EGC37019.1 - 0.075 12.6 2.4 3.5 7.1 0.1 2.0 1 1 1 2 2 2 0 Cas9 alpha-helical lobe domain CCDC84 PF14968.6 EGC37019.1 - 0.1 12.2 4.9 0.12 12.0 4.9 1.0 1 0 0 1 1 1 0 Coiled coil protein 84 PI3_PI4_kinase PF00454.27 EGC37020.1 - 1.1e-55 189.1 0.2 3.8e-55 187.4 0.2 2.0 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.23 EGC37020.1 - 2.8e-34 118.9 4.6 2.8e-34 118.9 4.6 2.9 2 0 0 2 2 2 1 FAT domain UME PF08064.13 EGC37020.1 - 6.7e-16 58.1 3.7 5.3e-15 55.2 0.7 4.1 3 0 0 3 3 3 1 UME (NUC010) domain FATC PF02260.20 EGC37020.1 - 1.7e-14 53.3 1.9 9.9e-14 50.9 0.3 2.6 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.6 EGC37020.1 - 0.00098 19.6 0.1 0.0034 17.9 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat QueH PF02677.14 EGC37020.1 - 0.026 14.7 1.0 0.14 12.2 1.0 2.4 1 0 0 1 1 1 0 Epoxyqueuosine reductase QueH TPR_2 PF07719.17 EGC37020.1 - 0.16 12.1 0.3 5.2 7.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3385 PF11865.8 EGC37020.1 - 0.98 9.3 0.0 0.98 9.3 0.0 5.8 6 1 0 6 6 6 0 Domain of unknown function (DUF3385) Tom22 PF04281.13 EGC37020.1 - 2.9 7.7 7.9 0.16 11.8 1.4 2.3 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 TIG PF01833.24 EGC37021.1 - 1.9e-11 43.9 6.2 9.4e-05 22.4 0.2 3.7 2 1 0 2 2 2 2 IPT/TIG domain EGF_2 PF07974.13 EGC37021.1 - 0.0001 22.6 49.4 0.047 14.1 13.3 4.1 2 1 1 3 3 3 3 EGF-like domain Tox-MPTase3 PF15639.6 EGC37021.1 - 0.073 12.9 0.1 0.62 9.9 0.0 2.3 2 0 0 2 2 2 0 Metallopeptidase toxin 3 Laminin_EGF PF00053.24 EGC37021.1 - 2.5 8.3 33.8 0.32 11.2 10.5 3.1 3 0 0 3 3 3 0 Laminin EGF domain HEAT PF02985.22 EGC37022.1 - 6.9e-11 41.4 0.7 0.13 12.6 0.0 7.8 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.6 EGC37022.1 - 2.3e-10 40.7 0.0 0.34 11.3 0.0 6.3 5 1 1 6 6 6 2 HEAT repeats Importin_rep_4 PF18808.1 EGC37022.1 - 1.7e-07 31.4 0.3 1.7e-07 31.4 0.3 3.7 4 0 0 4 4 3 1 Importin repeat Cnd1 PF12717.7 EGC37022.1 - 4.3e-07 30.1 1.1 0.12 12.5 0.0 4.5 4 1 0 4 4 4 2 non-SMC mitotic condensation complex subunit 1 HEAT_EZ PF13513.6 EGC37022.1 - 6.7e-07 29.7 0.0 2.9 8.5 0.0 6.9 6 0 0 6 6 6 1 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGC37022.1 - 9.4e-07 29.4 0.3 0.42 11.3 0.0 5.4 3 1 2 5 5 5 2 Vacuolar 14 Fab1-binding region RIX1 PF08167.12 EGC37022.1 - 0.00022 21.0 0.0 0.41 10.4 0.0 4.1 4 1 1 5 5 5 1 rRNA processing/ribosome biogenesis CLASP_N PF12348.8 EGC37022.1 - 0.0003 20.5 0.1 0.01 15.4 0.0 3.1 2 1 1 3 3 3 1 CLASP N terminal DUF1981 PF09324.10 EGC37022.1 - 0.0016 18.3 0.7 2.5 8.0 0.0 4.5 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) PDDEXK_10 PF07788.11 EGC37022.1 - 0.0027 17.6 0.0 0.36 10.8 0.0 2.8 2 0 0 2 2 2 1 PD-(D/E)XK nuclease superfamily RICTOR_V PF14668.6 EGC37022.1 - 0.0031 17.7 0.6 9.5 6.5 0.0 4.6 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Tti2 PF10521.9 EGC37022.1 - 0.0054 16.3 0.0 0.74 9.3 0.0 3.9 3 2 2 5 5 5 1 Tti2 family Sec7_N PF12783.7 EGC37022.1 - 0.0084 16.0 4.8 2.1 8.2 0.5 4.3 5 1 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DNA_alkylation PF08713.11 EGC37022.1 - 0.084 12.6 0.0 0.22 11.2 0.0 1.6 1 0 0 1 1 1 0 DNA alkylation repair enzyme DUF4042 PF13251.6 EGC37022.1 - 0.14 11.9 0.1 31 4.2 0.0 4.3 5 1 0 5 5 5 0 Domain of unknown function (DUF4042) Ras PF00071.22 EGC37023.1 - 3.2e-49 166.6 0.0 3.9e-49 166.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC37023.1 - 1e-30 106.4 0.0 1.8e-30 105.6 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC37023.1 - 3.4e-12 46.2 0.0 4.2e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC37023.1 - 5e-05 23.4 0.0 7.7e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.20 EGC37023.1 - 0.00047 19.4 1.1 0.44 9.7 0.1 2.6 2 1 1 3 3 3 2 G-protein alpha subunit Gtr1_RagA PF04670.12 EGC37023.1 - 0.00049 19.5 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.22 EGC37023.1 - 0.0012 19.3 0.2 0.022 15.2 0.2 2.2 1 1 0 1 1 1 1 RNA helicase GTP_EFTU PF00009.27 EGC37023.1 - 0.0039 16.8 0.0 0.013 15.0 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC37023.1 - 0.0087 16.0 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 1 RsgA GTPase DUF3426 PF11906.8 EGC37023.1 - 0.013 15.6 0.0 0.019 15.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3426) AAA_24 PF13479.6 EGC37023.1 - 0.045 13.5 0.0 0.089 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGC37023.1 - 0.079 12.1 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain TsaE PF02367.17 EGC37023.1 - 0.08 13.0 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_7 PF12775.7 EGC37023.1 - 0.084 12.4 0.0 0.14 11.6 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region Septin PF00735.18 EGC37023.1 - 0.17 11.2 0.1 0.32 10.2 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_33 PF13671.6 EGC37023.1 - 0.19 11.9 0.0 0.37 10.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain Med14 PF08638.11 EGC37024.1 - 1.5e-50 171.3 0.1 5.3e-50 169.5 0.1 2.0 1 1 0 1 1 1 1 Mediator complex subunit MED14 Peptidase_M24_C PF16188.5 EGC37024.1 - 0.075 13.1 0.5 2.8 8.1 0.0 3.3 3 0 0 3 3 3 0 C-terminal region of peptidase_M24 MCRS_N PF13325.6 EGC37024.1 - 0.23 11.4 2.7 0.44 10.5 0.2 2.4 2 0 0 2 2 2 0 N-terminal region of micro-spherule protein Copine PF07002.16 EGC37026.1 - 1.1e-50 172.2 0.0 1.4e-50 171.7 0.0 1.2 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC37026.1 - 1.4e-18 67.0 0.0 7.5e-08 32.6 0.2 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC37026.1 - 1.5e-05 25.2 0.0 4.1e-05 23.8 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_3 PF13768.6 EGC37026.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.5 1 0 0 1 1 1 0 von Willebrand factor type A domain Usp PF00582.26 EGC37027.1 - 2.1e-21 76.9 0.0 2.7e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family CAP PF00188.26 EGC37028.1 - 6.2e-11 43.2 4.2 6.2e-11 43.2 4.2 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Prenyltransf PF01255.19 EGC37029.1 - 1.4e-71 240.6 0.3 3.1e-71 239.5 0.3 1.6 1 0 0 1 1 1 1 Putative undecaprenyl diphosphate synthase Pkinase PF00069.25 EGC37029.1 - 5.1e-13 49.0 19.5 8.6e-12 45.0 9.4 3.1 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37029.1 - 2.5e-11 43.3 2.9 6e-11 42.1 2.4 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase TMEM192 PF14802.6 EGC37029.1 - 0.01 14.9 2.0 0.017 14.3 1.3 1.6 2 0 0 2 2 2 0 TMEM192 family FNIP PF05725.12 EGC37030.1 - 3.9e-51 171.0 92.5 6.3e-12 45.5 1.3 7.5 1 1 8 9 9 9 8 FNIP Repeat Pkinase PF00069.25 EGC37031.1 - 3.3e-05 23.4 0.7 7.4e-05 22.2 0.6 1.5 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37031.1 - 0.002 17.5 0.1 0.0041 16.4 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Robl_LC7 PF03259.17 EGC37032.1 - 0.0042 16.8 0.1 0.018 14.8 0.1 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain LAMTOR5 PF16672.5 EGC37032.1 - 0.037 14.0 0.0 0.057 13.4 0.0 1.3 1 1 0 1 1 1 0 Ragulator complex protein LAMTOR5 Closter_coat PF01785.17 EGC37032.1 - 0.068 12.4 0.2 0.068 12.4 0.2 1.2 1 0 0 1 1 1 0 Closterovirus coat protein DUF4883 PF16224.5 EGC37032.1 - 0.1 12.9 0.5 0.11 12.8 0.5 1.3 1 1 0 1 1 1 0 DOmain of unknown function (DUF4883) LRR_6 PF13516.6 EGC37034.1 - 1.4e-09 37.2 38.0 0.061 13.4 0.2 10.9 11 0 0 11 11 11 7 Leucine Rich repeat Lipase_3 PF01764.25 EGC37035.1 - 5.4e-25 87.9 0.0 3e-24 85.5 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 EGC37035.1 - 0.027 14.0 0.1 0.13 11.8 0.0 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) DUF676 PF05057.14 EGC37035.1 - 0.033 13.7 0.0 0.067 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.20 EGC37035.1 - 0.073 12.7 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC37035.1 - 0.14 12.7 0.0 0.2 12.3 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L13e PF01294.18 EGC37036.1 - 5.3e-67 225.2 5.5 1.2e-66 224.0 5.5 1.6 1 0 0 1 1 1 1 Ribosomal protein L13e Rep_fac_C PF08542.11 EGC37036.1 - 2.2e-15 56.8 0.0 5.4e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 Replication factor C C-terminal domain AAA PF00004.29 EGC37036.1 - 4.5e-13 49.8 0.0 1.1e-12 48.5 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DNA_pol3_delta2 PF13177.6 EGC37036.1 - 7e-13 48.7 0.0 9.5e-10 38.5 0.1 2.6 1 1 1 2 2 2 2 DNA polymerase III, delta subunit AAA_14 PF13173.6 EGC37036.1 - 3.2e-07 30.4 0.0 7.8e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC37036.1 - 1.2e-06 29.0 0.0 0.00025 21.5 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain Rad17 PF03215.15 EGC37036.1 - 3.8e-06 26.9 0.0 2.7e-05 24.2 0.0 2.3 2 1 1 3 3 2 1 Rad17 P-loop domain AAA_22 PF13401.6 EGC37036.1 - 1.5e-05 25.2 0.2 0.0098 16.2 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC37036.1 - 6.9e-05 22.9 0.0 0.00015 21.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_11 PF13086.6 EGC37036.1 - 6.9e-05 22.8 1.3 0.0007 19.5 0.0 2.5 2 1 0 2 2 2 1 AAA domain Viral_helicase1 PF01443.18 EGC37036.1 - 8.1e-05 22.5 0.0 0.00018 21.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_assoc_2 PF16193.5 EGC37036.1 - 0.00048 20.4 0.0 0.0029 17.9 0.0 2.4 2 0 0 2 2 1 1 AAA C-terminal domain NTPase_1 PF03266.15 EGC37036.1 - 0.00053 19.9 0.1 0.11 12.4 0.0 2.5 2 0 0 2 2 2 1 NTPase DNA_pol3_delta PF06144.13 EGC37036.1 - 0.00089 19.1 0.1 0.0022 17.8 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Mg_chelatase PF01078.21 EGC37036.1 - 0.0013 18.2 0.0 0.012 15.0 0.0 2.2 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGC37036.1 - 0.0015 18.3 0.0 0.0031 17.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC37036.1 - 0.002 18.4 0.2 0.019 15.2 0.0 2.4 2 1 1 3 3 2 1 AAA domain AAA_19 PF13245.6 EGC37036.1 - 0.0022 18.3 0.2 0.018 15.3 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGC37036.1 - 0.0026 17.3 0.0 0.0043 16.6 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region AAA_18 PF13238.6 EGC37036.1 - 0.0051 17.4 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.22 EGC37036.1 - 0.0061 16.9 0.0 0.072 13.5 0.0 2.6 3 0 0 3 3 2 1 RNA helicase AAA_3 PF07726.11 EGC37036.1 - 0.011 15.6 0.0 0.047 13.6 0.0 2.0 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) TniB PF05621.11 EGC37036.1 - 0.011 15.2 0.0 4.4 6.7 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_30 PF13604.6 EGC37036.1 - 0.012 15.4 0.6 0.05 13.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain T2SSE PF00437.20 EGC37036.1 - 0.023 13.8 0.0 0.049 12.7 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.12 EGC37036.1 - 0.023 14.4 0.0 0.084 12.6 0.0 2.0 1 1 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain IstB_IS21 PF01695.17 EGC37036.1 - 0.025 14.3 0.0 0.068 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein MCM PF00493.23 EGC37036.1 - 0.027 13.6 0.0 0.059 12.4 0.0 1.6 1 0 0 1 1 1 0 MCM P-loop domain AAA_25 PF13481.6 EGC37036.1 - 0.033 13.8 0.1 0.16 11.5 0.1 2.0 1 1 1 2 2 2 0 AAA domain DEAD PF00270.29 EGC37036.1 - 0.044 13.5 0.5 2.9 7.6 0.0 2.8 2 1 1 3 3 3 0 DEAD/DEAH box helicase ATPase_2 PF01637.18 EGC37036.1 - 0.061 13.2 0.7 0.25 11.2 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea ABC_tran PF00005.27 EGC37036.1 - 0.074 13.6 0.1 0.3 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter Nodulin_late PF07127.11 EGC37037.1 - 0.049 14.0 2.6 0.049 14.0 2.6 4.6 3 1 1 4 4 4 0 Late nodulin protein DUF1682 PF07946.14 EGC37038.1 - 5.9e-81 272.2 6.3 5.9e-81 272.2 6.3 1.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1682) DRY_EERY PF09750.9 EGC37038.1 - 2.1 8.6 8.5 4.8 7.5 8.5 1.6 1 0 0 1 1 1 0 Alternative splicing regulator SLATT_5 PF18160.1 EGC37038.1 - 2.1 7.6 5.9 3.1 7.1 2.9 2.4 2 0 0 2 2 2 0 SMODS and SLOG-associating 2TM effector domain family 5 OAD_gamma PF04277.13 EGC37038.1 - 2.3 8.8 0.0 2.3 8.8 0.0 3.1 3 1 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain Noggin PF05806.12 EGC37038.1 - 2.5 8.0 6.8 4.5 7.1 6.8 1.3 1 0 0 1 1 1 0 Noggin C2 PF00168.30 EGC37039.1 - 2.3e-19 69.6 0.4 5.5e-19 68.4 0.4 1.7 1 0 0 1 1 1 1 C2 domain zf-RING_2 PF13639.6 EGC37039.1 - 6.1e-06 26.5 4.7 6.1e-06 26.5 4.7 7.9 5 2 0 6 6 6 2 Ring finger domain zf-RING_UBOX PF13445.6 EGC37039.1 - 0.00011 22.1 0.9 0.00011 22.1 0.9 6.6 8 0 0 8 8 8 3 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC37039.1 - 0.00018 21.3 0.7 0.00018 21.3 0.7 6.9 8 0 0 8 8 8 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37039.1 - 0.00093 19.1 6.2 0.00093 19.1 6.2 7.1 7 3 1 8 8 8 2 zinc-RING finger domain zf-RING_11 PF17123.5 EGC37039.1 - 0.0011 18.7 3.9 0.0011 18.7 3.9 4.5 4 0 0 4 4 4 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGC37039.1 - 0.0095 15.8 5.9 0.0095 15.8 5.9 8.2 6 2 1 7 7 7 2 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37039.1 - 0.017 15.4 2.1 0.017 15.4 2.1 6.1 5 1 0 6 6 6 0 RING-H2 zinc finger domain F-box-like PF12937.7 EGC37040.1 - 5.1e-07 29.5 0.3 1.6e-06 27.9 0.1 2.0 2 0 0 2 2 2 1 F-box-like Cullin PF00888.22 EGC37040.1 - 2.7e-06 26.3 0.1 2.7e-06 26.3 0.1 2.4 3 0 0 3 3 3 1 Cullin family F-box PF00646.33 EGC37040.1 - 0.0021 17.9 0.2 0.0088 15.9 0.0 2.1 2 0 0 2 2 2 1 F-box domain SRA1 PF07304.11 EGC37040.1 - 0.77 9.5 2.9 1.4 8.7 2.9 1.4 1 0 0 1 1 1 0 Steroid receptor RNA activator (SRA1) CAP_N PF01213.19 EGC37040.1 - 1.5 8.3 11.5 4.6 6.6 11.5 1.8 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Sugarporin_N PF11471.8 EGC37041.1 - 0.05 13.6 0.3 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Maltoporin periplasmic N-terminal extension DUF4131 PF13567.6 EGC37042.1 - 0.045 13.4 0.0 0.045 13.4 0.0 3.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Pex14_N PF04695.13 EGC37042.1 - 0.11 13.1 4.7 0.19 12.4 0.1 2.7 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region RNA12 PF10443.9 EGC37043.1 - 1.7e-14 53.4 8.4 6.4e-10 38.3 3.7 2.6 3 0 0 3 3 3 2 RNA12 protein ATPase_2 PF01637.18 EGC37043.1 - 8.7e-07 29.1 0.0 8.7e-07 29.1 0.0 3.3 3 1 0 3 3 3 1 ATPase domain predominantly from Archaea Adeno_IVa2 PF02456.15 EGC37043.1 - 0.00067 18.6 0.1 0.0019 17.1 0.1 1.7 1 1 0 1 1 1 1 Adenovirus IVa2 protein AAA_16 PF13191.6 EGC37043.1 - 0.0029 18.0 0.0 0.01 16.3 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC37043.1 - 0.0048 17.2 0.0 0.012 15.9 0.0 1.7 1 0 0 1 1 1 1 AAA domain DNA_pol3_theta PF06440.11 EGC37043.1 - 0.015 14.9 0.5 0.055 13.1 0.0 2.1 2 0 0 2 2 2 0 DNA polymerase III, theta subunit Viral_helicase1 PF01443.18 EGC37043.1 - 0.049 13.4 0.4 0.14 11.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.6 EGC37043.1 - 0.15 12.6 1.5 0.61 10.6 0.0 2.8 3 0 0 3 3 3 0 AAA domain GrpE PF01025.19 EGC37043.1 - 1.2 8.8 18.1 0.12 12.0 0.2 4.5 4 1 0 4 4 4 0 GrpE PetL PF05115.14 EGC37044.1 - 1 9.4 15.0 1.9 8.5 0.2 3.5 3 1 0 3 3 3 0 Cytochrome B6-F complex subunit VI (PetL) Ctr PF04145.15 EGC37045.1 - 0.062 13.9 5.8 0.21 12.2 5.8 1.9 1 1 0 1 1 1 0 Ctr copper transporter family SNAPc_SNAP43 PF09808.9 EGC37046.1 - 5.8e-35 120.9 1.7 1.1e-34 120.1 1.7 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 HlyIII PF03006.20 EGC37047.1 - 4e-37 128.1 12.9 4.8e-37 127.8 12.9 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4131 PF13567.6 EGC37047.1 - 5.3 6.7 5.7 77 2.9 4.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) GST_N PF02798.20 EGC37048.1 - 5.2e-09 36.3 0.0 9.5e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC37048.1 - 1.7e-08 34.6 0.0 3.2e-08 33.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC37048.1 - 1.1e-07 32.1 0.0 2.1e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC37048.1 - 5.7e-06 26.5 0.0 1.6e-05 25.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC37048.1 - 0.00032 20.6 0.0 0.00058 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC37048.1 - 0.0011 19.1 0.1 0.0021 18.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC37048.1 - 0.013 15.3 0.2 0.097 12.5 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Glutaredoxin2_C PF04399.13 EGC37048.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.3 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain PBD PF00786.28 EGC37049.1 - 3e-22 78.7 0.3 6.5e-22 77.7 0.3 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain WH1 PF00568.23 EGC37049.1 - 3.8e-18 65.4 0.4 5.9e-18 64.8 0.4 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.20 EGC37049.1 - 4.1e-05 23.3 0.5 9.4e-05 22.1 0.5 1.6 1 0 0 1 1 1 1 WH2 motif DUF2076 PF09849.9 EGC37049.1 - 0.2 11.7 6.1 0.088 12.8 3.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) PCI PF01399.27 EGC37050.1 - 4.9e-16 59.1 0.4 4.9e-16 59.1 0.4 3.0 3 1 0 3 3 3 1 PCI domain CSN4_RPN5_eIF3a PF18420.1 EGC37050.1 - 6.5e-07 29.4 0.2 1.7e-06 28.0 0.2 1.8 1 0 0 1 1 1 1 CSN4/RPN5/eIF3a helix turn helix domain TPR_19 PF14559.6 EGC37050.1 - 0.047 14.2 0.0 0.18 12.3 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2281 PF10047.9 EGC37050.1 - 0.06 14.1 0.5 2.2 9.1 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) EIIBC-GUT_N PF03612.14 EGC37051.1 - 6.5 6.5 7.1 2 8.1 2.8 2.0 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus NAD_binding_6 PF08030.12 EGC37052.1 - 0.26 11.4 3.7 0.33 11.1 0.0 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FNIP PF05725.12 EGC37053.1 - 8.8e-163 528.3 89.0 1.1e-13 51.2 0.4 16.1 13 2 0 15 15 15 15 FNIP Repeat DUF1769 PF08588.10 EGC37053.1 - 0.03 14.5 23.5 34 4.7 0.3 12.1 12 4 5 17 17 17 0 Protein of unknown function (DUF1769) EGF_2 PF07974.13 EGC37054.1 - 0.02 15.2 3.8 0.02 15.2 3.8 5.8 6 1 0 6 6 6 0 EGF-like domain EGF PF00008.27 EGC37054.1 - 5.1 7.5 51.7 0.15 12.4 10.0 5.1 4 0 0 4 4 4 0 EGF-like domain Prog_receptor PF02161.15 EGC37055.1 - 0.21 10.3 2.3 0.22 10.2 1.4 1.3 1 1 0 1 1 1 0 Progesterone receptor zf-NF-X1 PF01422.17 EGC37056.1 - 2.2e-09 37.2 56.3 2.3e-05 24.4 16.5 13.5 13 1 1 14 14 14 7 NF-X1 type zinc finger NCBP3 PF10309.9 EGC37056.1 - 0.015 15.2 0.0 0.033 14.1 0.0 1.5 1 0 0 1 1 1 0 Nuclear cap-binding protein subunit 3 polyprenyl_synt PF00348.17 EGC37057.1 - 9.4e-63 211.6 0.0 1.1e-62 211.4 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase zf-CCCH_6 PF18585.1 EGC37057.1 - 0.11 12.4 0.1 0.21 11.5 0.1 1.5 1 0 0 1 1 1 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 2 TPR_2 PF07719.17 EGC37058.1 - 3.9e-12 45.3 1.1 0.0043 17.0 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat SET PF00856.28 EGC37058.1 - 7.9e-12 45.9 1.1 1.9e-11 44.6 1.1 1.6 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.28 EGC37058.1 - 1.1e-10 40.8 5.6 0.00025 20.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37058.1 - 5.6e-08 32.4 10.6 0.0032 17.5 0.2 3.9 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC37058.1 - 1.1e-07 31.4 5.2 0.0017 18.0 0.8 2.5 2 0 0 2 2 2 2 TPR repeat TPR_12 PF13424.6 EGC37058.1 - 7.3e-06 26.2 0.4 9.3e-05 22.7 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC37058.1 - 3.5e-05 24.4 0.0 0.016 15.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC37058.1 - 0.00045 20.7 1.4 7.7 7.4 0.1 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_3 PF07720.12 EGC37058.1 - 0.00075 19.4 0.1 0.0023 17.9 0.1 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat MIT PF04212.18 EGC37058.1 - 0.0021 18.1 6.0 0.015 15.3 0.0 3.5 3 1 1 4 4 4 1 MIT (microtubule interacting and transport) domain TPR_19 PF14559.6 EGC37058.1 - 0.0052 17.3 0.7 1.2 9.7 0.1 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC37058.1 - 0.0054 17.0 0.5 4.1 8.0 0.1 4.1 4 1 1 5 5 4 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC37058.1 - 0.0068 16.4 0.1 0.045 13.8 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC37058.1 - 0.015 16.1 0.0 8.7 7.5 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-MYND PF01753.18 EGC37058.1 - 0.015 15.4 11.1 0.015 15.4 11.1 2.1 2 0 0 2 2 1 0 MYND finger ANAPC3 PF12895.7 EGC37058.1 - 0.02 15.1 1.6 0.72 10.1 0.6 3.0 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.9 EGC37058.1 - 0.04 13.6 0.1 0.074 12.7 0.1 1.5 1 0 0 1 1 1 0 26S proteasome subunit RPN7 Prefoldin PF02996.17 EGC37058.1 - 0.12 12.3 2.0 0.54 10.2 0.2 2.7 1 1 1 2 2 2 0 Prefoldin subunit YfdX PF10938.8 EGC37058.1 - 0.15 12.0 0.0 0.79 9.6 0.0 2.2 2 0 0 2 2 2 0 YfdX protein DUF334 PF03904.13 EGC37058.1 - 2.2 7.8 7.4 2.6 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) tRNA_U5-meth_tr PF05958.11 EGC37059.1 - 1.9e-15 56.7 0.3 9.9e-15 54.4 0.0 2.2 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.6 EGC37059.1 - 2.2e-07 30.8 0.0 4.9e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37059.1 - 2.7e-05 24.8 0.0 8.2e-05 23.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC37059.1 - 0.00022 20.8 0.0 0.00022 20.8 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.15 EGC37059.1 - 0.00032 20.4 0.0 0.0009 18.9 0.0 1.7 1 0 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_4 PF02390.17 EGC37059.1 - 0.0047 16.4 0.0 0.017 14.6 0.0 2.0 1 0 0 1 1 1 1 Putative methyltransferase PrmA PF06325.13 EGC37059.1 - 0.0067 15.8 0.0 0.0067 15.8 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) RRM_1 PF00076.22 EGC37059.1 - 0.0085 15.9 0.5 0.044 13.6 0.5 2.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PCMT PF01135.19 EGC37059.1 - 0.041 13.6 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_23 PF13489.6 EGC37059.1 - 0.042 13.7 0.0 0.098 12.5 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGC37059.1 - 0.17 12.6 0.0 0.49 11.1 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGC37059.1 - 0.33 11.7 0.0 0.33 11.7 0.0 3.5 3 1 0 3 3 2 0 Methyltransferase domain FAA_hydrolase PF01557.18 EGC37060.1 - 1.1e-67 228.0 0.0 1.3e-67 227.7 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family Ribosomal_L50 PF10501.9 EGC37060.1 - 0.012 15.8 0.1 0.024 14.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal subunit 39S ATP13 PF12921.7 EGC37063.1 - 0.0036 17.2 0.5 0.0063 16.4 0.2 1.6 1 1 0 1 1 1 1 Mitochondrial ATPase expression DDE_3 PF13358.6 EGC37063.1 - 0.024 14.4 0.9 0.036 13.8 0.9 1.3 1 0 0 1 1 1 0 DDE superfamily endonuclease DUF3784 PF12650.7 EGC37064.1 - 0.0081 16.3 1.6 0.0081 16.3 1.6 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF3784) DUF2456 PF10445.9 EGC37064.1 - 0.0084 16.2 1.1 0.42 10.7 0.3 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2456) NADH_u_ox_C PF12853.7 EGC37064.1 - 0.077 13.0 0.0 3.2 7.8 0.0 2.8 3 0 0 3 3 3 0 C-terminal of NADH-ubiquinone oxidoreductase 21 kDa subunit Dickkopf_N PF04706.12 EGC37066.1 - 4.6 7.8 60.2 0.12 12.9 2.6 6.0 4 2 1 5 5 5 0 Dickkopf N-terminal cysteine-rich region IQ PF00612.27 EGC37068.1 - 3.8e-11 41.8 7.5 3.6e-05 23.2 0.3 2.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif WW PF00397.26 EGC37068.1 - 2.9e-05 24.1 0.7 6.1e-05 23.0 0.7 1.6 1 0 0 1 1 1 1 WW domain RPEL PF02755.15 EGC37068.1 - 0.028 14.1 0.0 0.061 13.0 0.0 1.6 1 0 0 1 1 1 0 RPEL repeat GLTT PF01744.20 EGC37068.1 - 0.73 9.6 14.4 12 5.8 0.6 5.2 2 1 5 8 8 8 0 GLTT repeat (6 copies) TUDOR PF00567.24 EGC37069.1 - 2.3e-09 37.3 0.1 6.4e-09 35.9 0.1 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.12 EGC37069.1 - 7.1e-08 32.0 3.6 7.1e-08 32.0 3.6 2.9 1 1 1 2 2 2 1 Survival motor neuron protein (SMN) Agenet PF05641.12 EGC37069.1 - 0.007 16.8 0.7 0.014 15.8 0.0 1.8 2 0 0 2 2 2 1 Agenet domain DUF4537 PF15057.6 EGC37069.1 - 0.053 13.5 0.0 0.12 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4537) HD_2 PF12917.7 EGC37069.1 - 0.76 9.5 4.0 2 8.1 0.1 2.2 2 0 0 2 2 2 0 HD containing hydrolase-like enzyme Acyl_transf_1 PF00698.21 EGC37071.1 - 1.6e-18 67.3 0.0 2e-18 67.0 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain CBM49 PF09478.10 EGC37072.1 - 1.4e-08 34.9 1.6 2.9e-08 33.9 1.6 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 EGF_2 PF07974.13 EGC37073.1 - 3.1e-06 27.4 44.5 0.0015 18.9 11.8 3.7 3 0 0 3 3 3 3 EGF-like domain TIG PF01833.24 EGC37073.1 - 4.1e-06 26.8 15.6 0.00053 20.0 1.5 4.6 4 2 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.13 EGC37075.1 - 0.00092 19.5 9.5 0.00092 19.5 9.5 4.1 4 0 0 4 4 4 2 EGF-like domain hEGF PF12661.7 EGC37075.1 - 0.0071 16.9 5.4 0.0071 16.9 5.4 4.4 4 0 0 4 4 4 1 Human growth factor-like EGF Pkinase PF00069.25 EGC37076.1 - 1.8e-70 237.3 0.1 2.4e-50 171.4 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37076.1 - 1.4e-29 103.2 0.0 1.7e-26 93.1 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase FHA PF00498.26 EGC37076.1 - 4.3e-16 59.0 0.6 1.7e-15 57.1 0.6 2.1 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC37076.1 - 1.2e-06 28.7 0.0 3.4e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain Kdo PF06293.14 EGC37076.1 - 0.00019 20.9 0.0 0.00035 20.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC37076.1 - 0.00044 19.6 0.0 0.35 10.1 0.0 2.4 2 0 0 2 2 2 2 Kinase-like PrmA PF06325.13 EGC37077.1 - 7.8e-06 25.5 0.0 1.6e-05 24.5 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) MTS PF05175.14 EGC37077.1 - 7.8e-05 22.3 0.1 0.0028 17.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGC37077.1 - 0.0029 17.5 0.0 0.0061 16.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37077.1 - 0.0058 16.4 0.1 0.027 14.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37077.1 - 0.0095 16.6 0.0 0.037 14.7 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_10 PF05971.12 EGC37077.1 - 0.019 14.3 0.2 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 RNA methyltransferase Methyltransf_12 PF08242.12 EGC37077.1 - 2.6 8.9 0.0 2.6 8.9 0.0 3.7 4 0 0 4 4 4 0 Methyltransferase domain HPP PF04982.13 EGC37078.1 - 0.068 13.4 0.9 0.16 12.2 0.9 1.6 1 0 0 1 1 1 0 HPP family MBG_2 PF18676.1 EGC37079.1 - 0.031 14.9 0.1 0.081 13.6 0.1 1.7 1 1 0 1 1 1 0 MBG domain (YGX type) Mis12 PF05859.12 EGC37080.1 - 0.061 13.4 0.2 0.1 12.6 0.2 1.4 1 0 0 1 1 1 0 Mis12 protein Nbl1_Borealin_N PF10444.9 EGC37081.1 - 5.2e-08 32.4 1.8 1.1e-07 31.3 1.8 1.6 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal mRNA_decap_C PF16741.5 EGC37081.1 - 0.058 12.7 4.8 0.11 11.8 0.1 3.0 2 0 0 2 2 2 0 mRNA-decapping enzyme C-terminus FtsX PF02687.21 EGC37082.1 - 1.8e-14 53.9 26.3 2e-10 41.0 11.2 6.3 6 1 0 6 6 6 2 FtsX-like permease family DUF2535 PF10751.9 EGC37082.1 - 0.012 16.1 2.1 0.64 10.6 0.0 3.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2535) NST1 PF13945.6 EGC37082.1 - 2.7 8.1 12.4 5.1 7.2 12.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator ketoacyl-synt PF00109.26 EGC37083.1 - 1e-62 212.0 0.0 1.7e-62 211.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC37083.1 - 1.2e-33 117.0 0.0 2.1e-33 116.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC37083.1 - 5.4e-32 110.3 0.0 1.3e-31 109.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC37083.1 - 2.3e-22 79.8 0.0 4.1e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC37083.1 - 1.5e-17 64.2 0.0 6.2e-17 62.2 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC37083.1 - 1.3e-12 48.2 0.3 3.8e-12 46.7 0.3 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGC37083.1 - 4.2e-09 36.5 0.0 1.3e-08 34.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.6 EGC37083.1 - 4.5e-09 36.0 0.0 7e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.12 EGC37083.1 - 4.8e-09 36.1 0.0 9.9e-09 35.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC37083.1 - 6.8e-08 33.1 0.0 2.2e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC37083.1 - 1.2e-07 32.0 0.0 3.7e-07 30.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGC37083.1 - 5.1e-06 26.4 1.3 4.3e-05 23.4 0.1 2.7 1 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37083.1 - 1e-05 26.1 0.0 3.7e-05 24.4 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC37083.1 - 1.1e-05 26.5 0.0 6.1e-05 24.1 0.0 2.3 3 0 0 3 3 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 EGC37083.1 - 4.2e-05 23.0 1.1 0.00013 21.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Thiolase_N PF00108.23 EGC37083.1 - 0.0075 15.6 0.1 0.014 14.8 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.25 EGC37083.1 - 0.029 13.8 0.0 0.18 11.3 0.0 2.2 2 0 0 2 2 2 0 short chain dehydrogenase Yuri_gagarin PF15934.5 EGC37084.1 - 0.0013 18.6 8.7 0.0014 18.5 8.7 1.1 1 0 0 1 1 1 1 Yuri gagarin MscS_porin PF12795.7 EGC37084.1 - 0.0023 17.5 12.9 0.0037 16.8 12.9 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain CENP-F_leu_zip PF10473.9 EGC37084.1 - 0.011 15.8 15.6 0.016 15.2 15.6 1.4 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HemX PF04375.14 EGC37084.1 - 0.017 14.5 6.6 0.019 14.2 6.6 1.2 1 0 0 1 1 1 0 HemX, putative uroporphyrinogen-III C-methyltransferase Fez1 PF06818.15 EGC37084.1 - 0.048 14.1 10.0 0.057 13.9 10.0 1.0 1 0 0 1 1 1 0 Fez1 Phage_GP20 PF06810.11 EGC37084.1 - 0.079 12.8 18.2 0.44 10.3 12.2 2.8 1 1 2 3 3 3 0 Phage minor structural protein GP20 FTO_NTD PF12933.7 EGC37084.1 - 0.097 11.9 2.9 0.11 11.7 2.9 1.1 1 0 0 1 1 1 0 FTO catalytic domain MAAL_C PF07476.11 EGC37084.1 - 0.11 11.6 3.8 0.18 11.0 0.7 1.9 1 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus HMMR_N PF15905.5 EGC37084.1 - 0.12 11.9 13.5 0.17 11.4 13.5 1.3 1 0 0 1 1 1 0 Hyaluronan mediated motility receptor N-terminal Phage_int_SAM_2 PF12834.7 EGC37084.1 - 0.13 13.0 3.2 0.11 13.2 1.7 1.7 2 0 0 2 2 2 0 Phage integrase, N-terminal Atg14 PF10186.9 EGC37084.1 - 0.14 11.3 11.4 0.19 10.8 11.4 1.1 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FliD_N PF02465.18 EGC37084.1 - 0.14 12.8 4.9 0.084 13.6 1.2 2.0 1 1 1 2 2 2 0 Flagellar hook-associated protein 2 N-terminus Mod_r PF07200.13 EGC37084.1 - 0.18 11.9 17.0 0.18 11.9 16.1 1.3 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein FapA PF03961.13 EGC37084.1 - 0.19 10.3 12.5 0.2 10.2 12.5 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A SAM_KSR1 PF13543.6 EGC37084.1 - 0.24 11.6 7.7 0.33 11.1 7.7 1.1 1 0 0 1 1 1 0 SAM like domain present in kinase suppressor RAS 1 Exonuc_VII_L PF02601.15 EGC37084.1 - 0.37 10.3 5.7 0.43 10.1 5.7 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit V_ATPase_I PF01496.19 EGC37084.1 - 0.43 8.5 8.9 0.47 8.3 8.9 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family TMPIT PF07851.13 EGC37084.1 - 0.78 8.9 7.6 0.89 8.7 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein NPV_P10 PF05531.12 EGC37084.1 - 1.6 9.2 11.9 1.9 9.0 3.9 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein USP8_interact PF08941.10 EGC37084.1 - 3 7.6 7.3 4.9 6.9 6.7 1.6 1 1 1 2 2 2 0 USP8 interacting Med4 PF10018.9 EGC37084.1 - 3 7.5 12.4 3.8 7.1 12.4 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 DUF3430 PF11912.8 EGC37086.1 - 2.1e-32 112.9 32.1 2.5e-32 112.6 32.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) zf-C6H2 PF15801.5 EGC37086.1 - 0.41 11.0 3.8 0.87 9.9 3.8 1.6 1 0 0 1 1 1 0 zf-MYND-like zinc finger, mRNA-binding GDI PF00996.18 EGC37087.1 - 2e-214 712.0 0.5 2.2e-214 711.8 0.5 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.24 EGC37087.1 - 4.4e-05 23.0 0.0 6.3e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase Hydrolase PF00702.26 EGC37088.1 - 1.4e-06 28.7 0.0 2.3e-06 28.1 0.0 1.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGC37088.1 - 0.047 13.8 0.0 0.073 13.1 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Rep_fac_C PF08542.11 EGC37088.1 - 0.12 12.7 0.0 0.25 11.8 0.0 1.5 1 0 0 1 1 1 0 Replication factor C C-terminal domain Ank_2 PF12796.7 EGC37089.1 - 5.7e-18 65.3 0.4 5.7e-13 49.3 0.1 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC37089.1 - 2.5e-11 43.8 0.2 8e-10 39.1 0.1 2.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC37089.1 - 3.2e-10 40.1 0.1 2.7e-05 24.3 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC37089.1 - 2.7e-09 36.5 0.0 0.0011 19.3 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeat Ank PF00023.30 EGC37089.1 - 7.4e-08 32.5 0.0 0.0082 16.6 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat WD40 PF00400.32 EGC37091.1 - 4.6e-20 71.6 11.0 2e-06 28.4 0.1 5.6 5 0 0 5 5 5 4 WD domain, G-beta repeat CAF1C_H4-bd PF12265.8 EGC37091.1 - 1.7e-18 66.6 0.6 5.4e-17 61.8 0.0 3.3 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex ANAPC4_WD40 PF12894.7 EGC37091.1 - 4.2e-08 33.4 1.1 0.0011 19.2 0.5 4.0 1 1 3 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain RNase_T PF00929.24 EGC37092.1 - 1.1e-10 42.3 0.3 3.4e-10 40.7 0.0 2.1 2 0 0 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.20 EGC37092.1 - 0.0018 18.0 0.1 0.0098 15.6 0.1 2.2 1 1 0 1 1 1 1 3'-5' exonuclease PAP_central PF04928.17 EGC37092.1 - 0.48 9.3 5.3 1 8.2 5.3 1.8 1 1 0 1 1 1 0 Poly(A) polymerase central domain BAG PF02179.16 EGC37092.1 - 0.78 10.2 4.8 0.27 11.7 0.4 2.6 2 0 0 2 2 2 0 BAG domain PAS_6 PF08348.11 EGC37092.1 - 1.6 8.6 4.7 0.37 10.7 0.2 2.3 3 0 0 3 3 3 0 YheO-like PAS domain WD40 PF00400.32 EGC37093.1 - 9.3e-16 58.0 7.2 0.00037 21.2 0.7 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37093.1 - 4e-11 43.1 0.2 0.015 15.6 0.0 4.8 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain DUF3439 PF11921.8 EGC37093.1 - 0.03 14.3 3.6 0.073 13.0 3.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DASH_Spc19 PF08287.11 EGC37093.1 - 2.2 8.1 5.6 5.9 6.8 5.7 1.7 1 1 0 1 1 1 0 Spc19 MGC-24 PF05283.11 EGC37093.1 - 2.2 8.7 10.8 4.2 7.8 10.8 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Mucin PF01456.17 EGC37093.1 - 5.8 6.9 16.9 11 6.0 16.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein FidL_like PF15941.5 EGC37093.1 - 6.2 7.3 8.7 0.54 10.7 0.5 2.6 2 0 0 2 2 2 0 FidL-like putative membrane protein PB1 PF00564.24 EGC37094.1 - 1.9e-07 30.9 0.2 3.4e-07 30.1 0.2 1.4 1 0 0 1 1 1 1 PB1 domain Ras PF00071.22 EGC37096.1 - 9.1e-25 87.1 0.4 1.1e-24 86.8 0.4 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC37096.1 - 1.2e-10 41.6 0.0 2.3e-10 40.7 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Aldo_ket_red PF00248.21 EGC37097.1 - 7.3e-50 169.8 0.5 1.5e-38 132.7 0.1 2.0 1 1 1 2 2 2 2 Aldo/keto reductase family DDE_Tnp_IS240 PF13610.6 EGC37097.1 - 0.03 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 DDE domain Aldo_ket_red PF00248.21 EGC37099.1 - 1.9e-50 171.7 0.8 1.8e-48 165.2 0.8 2.0 1 1 0 1 1 1 1 Aldo/keto reductase family E1-E2_ATPase PF00122.20 EGC37100.1 - 2.2e-35 121.8 0.2 2.2e-35 121.8 0.2 2.7 3 1 1 4 4 4 1 E1-E2 ATPase Hydrolase PF00702.26 EGC37100.1 - 5.4e-17 62.8 0.0 1.7e-08 35.0 0.0 3.3 3 0 0 3 3 3 3 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.8 EGC37100.1 - 4.8e-13 49.3 0.1 2.8e-12 46.9 0.1 2.4 1 0 0 1 1 1 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.26 EGC37100.1 - 0.0006 19.4 0.1 0.0014 18.3 0.1 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGC37100.1 - 0.009 16.1 0.0 0.02 15.0 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) LIM PF00412.22 EGC37101.1 - 1.5e-58 194.9 54.2 1.9e-15 56.8 0.8 5.2 5 0 0 5 5 5 5 LIM domain APG6_N PF17675.1 EGC37101.1 - 0.62 10.6 10.7 0.15 12.6 7.2 1.8 2 0 0 2 2 2 0 Apg6 coiled-coil region TIG PF01833.24 EGC37102.1 - 4e-06 26.8 0.7 4e-06 26.8 0.7 4.6 5 0 0 5 5 5 1 IPT/TIG domain EGF_2 PF07974.13 EGC37102.1 - 2.1e-05 24.8 25.7 0.0012 19.2 7.2 2.7 2 0 0 2 2 2 2 EGF-like domain PMP1_2 PF08114.11 EGC37102.1 - 0.011 15.4 2.5 0.025 14.3 2.5 1.5 1 0 0 1 1 1 0 ATPase proteolipid family Nop PF01798.18 EGC37103.1 - 1.5e-84 283.1 0.4 1.5e-84 283.1 0.4 2.9 3 2 1 4 4 4 1 snoRNA binding domain, fibrillarin NOP5NT PF08156.13 EGC37103.1 - 2.5e-16 59.8 0.1 2.5e-16 59.8 0.1 3.3 2 1 0 2 2 2 1 NOP5NT (NUC127) domain GSAP-16 PF14959.6 EGC37104.1 - 2.9e-30 104.3 2.4 6.4e-30 103.2 2.4 1.6 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term DUF3430 PF11912.8 EGC37105.1 - 3.3e-20 73.1 30.7 3.7e-20 72.9 30.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) THOC7 PF05615.13 EGC37106.1 - 2e-21 76.6 11.5 2e-21 76.6 11.5 2.1 1 1 1 2 2 2 1 Tho complex subunit 7 DUF948 PF06103.11 EGC37106.1 - 0.021 15.1 0.7 0.021 15.1 0.7 2.7 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-C4pol PF14260.6 EGC37106.1 - 1.8 9.1 7.2 0.62 10.6 0.9 2.7 1 1 1 2 2 2 0 C4-type zinc-finger of DNA polymerase delta DUF4407 PF14362.6 EGC37106.1 - 3.1 7.1 13.4 4.4 6.6 13.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) FNIP PF05725.12 EGC37107.1 - 2.1e-93 306.3 56.9 9.7e-11 41.7 0.1 12.6 4 2 8 14 14 14 14 FNIP Repeat Bacteroid_pep PF14406.6 EGC37107.1 - 0.082 13.3 0.0 0.25 11.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes VATC PF18716.1 EGC37108.1 - 0.11 12.4 1.3 0.23 11.3 1.3 1.5 1 0 0 1 1 1 0 Vms1-associating treble clef domain zf-CCHC PF00098.23 EGC37109.1 - 8.9e-06 25.6 1.3 2e-05 24.4 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle OSTbeta PF15048.6 EGC37109.1 - 0.0066 16.6 0.5 0.0066 16.6 0.5 2.2 2 1 0 2 2 2 1 Organic solute transporter subunit beta protein MAP17 PF15807.5 EGC37109.1 - 0.011 16.0 0.3 0.011 16.0 0.3 3.0 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 S_4TM PF18159.1 EGC37109.1 - 0.057 12.7 7.4 0.11 11.8 7.4 1.4 1 0 0 1 1 1 0 SMODS-associating 4TM effector domain ATP-synt_B PF00430.18 EGC37109.1 - 0.065 13.3 1.7 0.12 12.5 1.7 1.4 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) PTR2 PF00854.21 EGC37109.1 - 0.11 11.3 0.5 0.19 10.5 0.5 1.3 1 0 0 1 1 1 0 POT family zf-CCHC_5 PF14787.6 EGC37109.1 - 0.15 11.8 0.7 0.31 10.8 0.7 1.4 1 0 0 1 1 1 0 GAG-polyprotein viral zinc-finger DUF2232 PF09991.9 EGC37109.1 - 0.2 10.8 2.3 0.28 10.4 2.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FPN1 PF06963.12 EGC37109.1 - 0.25 9.9 3.1 0.35 9.4 3.1 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Pex24p PF06398.11 EGC37109.1 - 0.43 9.5 6.9 0.85 8.5 6.9 1.5 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Nucleoside_tran PF01733.18 EGC37109.1 - 0.53 9.6 5.3 0.09 12.1 1.2 1.6 2 0 0 2 2 2 0 Nucleoside transporter AI-2E_transport PF01594.16 EGC37109.1 - 4.5 6.3 5.3 6.9 5.7 5.3 1.3 1 0 0 1 1 1 0 AI-2E family transporter DUF4709 PF15821.5 EGC37110.1 - 2.3 8.5 5.1 2.9 8.2 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4709) XPG_N PF00752.17 EGC37111.1 - 3.4e-22 78.8 0.0 9.5e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.18 EGC37111.1 - 4.7e-19 68.5 0.3 4.7e-19 68.5 0.3 2.9 2 0 0 2 2 2 1 XPG I-region XPG_I_2 PF12813.7 EGC37111.1 - 0.00026 20.5 0.0 0.00051 19.6 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing 5_3_exonuc PF01367.20 EGC37111.1 - 0.0022 18.6 0.0 0.0075 16.8 0.0 1.9 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DnaJ_C PF01556.18 EGC37112.1 - 2.5e-34 118.5 1.0 3.4e-34 118.1 1.0 1.2 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ PF00226.31 EGC37112.1 - 7.5e-28 96.4 2.8 7.5e-28 96.4 2.8 1.6 2 0 0 2 2 2 1 DnaJ domain DnaJ_CXXCXGXG PF00684.19 EGC37112.1 - 3.7e-15 56.0 17.1 1e-14 54.7 17.1 1.8 1 0 0 1 1 1 1 DnaJ central domain Anti-TRAP PF15777.5 EGC37112.1 - 2.1e-06 27.6 7.3 0.015 15.2 0.9 2.5 2 0 0 2 2 2 2 Tryptophan RNA-binding attenuator protein inhibitory protein HypA PF01155.19 EGC37112.1 - 0.013 15.5 6.8 0.29 11.1 1.8 2.3 2 0 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA TackOD1 PF18551.1 EGC37112.1 - 0.033 13.8 5.5 0.49 10.0 0.4 2.3 1 1 1 2 2 2 0 Thaumarchaeal output domain 1 Cytochrome_C7 PF14522.6 EGC37112.1 - 1.3 9.0 11.2 19 5.3 9.0 2.5 1 1 1 2 2 2 0 Cytochrome c7 and related cytochrome c zinc-ribbons_6 PF07191.12 EGC37112.1 - 4.9 7.2 9.7 20 5.3 2.6 2.2 1 1 1 2 2 2 0 zinc-ribbons Cytochrom_c3_2 PF14537.6 EGC37112.1 - 6.6 7.3 10.2 5.8 7.5 4.0 2.4 1 1 1 2 2 2 0 Cytochrome c3 Pex14_N PF04695.13 EGC37113.1 - 0.012 16.3 17.1 0.016 15.9 17.1 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Spt20 PF12090.8 EGC37113.1 - 0.027 14.1 12.1 0.043 13.4 12.1 1.3 1 0 0 1 1 1 0 Spt20 family Kei1 PF08552.11 EGC37113.1 - 0.16 11.8 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF908 PF06012.12 EGC37113.1 - 8.6 5.7 6.4 11 5.3 6.4 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) Mtc PF03820.17 EGC37114.1 - 9.6e-115 382.9 0.1 1.1e-114 382.7 0.1 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PX PF00787.24 EGC37116.1 - 3.1e-12 46.5 0.6 3.1e-12 46.5 0.6 3.6 3 1 1 4 4 4 1 PX domain MMR_HSR1 PF01926.23 EGC37116.1 - 1.8e-05 24.8 0.1 0.00063 19.8 0.1 3.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC37116.1 - 8e-05 22.8 1.0 8e-05 22.8 1.0 6.1 4 3 0 4 4 4 1 Dynamin family Ank_4 PF13637.6 EGC37117.1 - 4.1e-14 52.7 0.1 5.2e-10 39.7 0.0 1.6 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC37117.1 - 4.6e-11 43.2 0.0 6e-11 42.8 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGC37117.1 - 1.3e-10 41.2 0.1 1.6e-08 34.6 0.1 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGC37117.1 - 3.7e-08 33.5 0.0 4.9e-08 33.1 0.0 1.2 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC37117.1 - 4.5e-07 29.7 0.0 9.3e-05 22.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat EGF_2 PF07974.13 EGC37118.1 - 5.3e-11 42.7 69.3 6.4e-05 23.2 15.3 4.8 4 0 0 4 4 4 4 EGF-like domain TIG PF01833.24 EGC37118.1 - 3.9e-05 23.7 26.9 0.0042 17.1 0.3 5.5 5 1 0 5 5 5 2 IPT/TIG domain EGF_Tenascin PF18720.1 EGC37118.1 - 0.022 14.8 41.0 0.099 12.7 6.7 4.6 4 0 0 4 4 4 0 Tenascin EGF domain LRR_1 PF00560.33 EGC37118.1 - 0.62 10.8 3.0 27 5.9 0.1 4.7 3 0 0 3 3 3 0 Leucine Rich Repeat Collectrin PF16959.5 EGC37118.1 - 6.3 6.5 7.6 1.5 8.6 3.3 2.1 2 0 0 2 2 2 0 Renal amino acid transporter JAB PF01398.21 EGC37119.1 - 1.1e-12 48.0 0.0 2.5e-12 46.8 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Streptin-Immun PF11083.8 EGC37119.1 - 0.47 10.9 8.0 0.38 11.2 1.7 2.7 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein Kinesin PF00225.23 EGC37120.1 - 6.2e-113 377.1 2.3 6.2e-113 377.1 2.3 2.5 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGC37120.1 - 3.2e-28 98.5 4.2 5.3e-28 97.8 0.3 3.2 2 1 0 2 2 2 1 Microtubule binding PRKG1_interact PF15898.5 EGC37120.1 - 0.014 16.3 12.3 0.014 16.3 12.3 6.5 2 2 4 6 6 6 0 cGMP-dependent protein kinase interacting domain DUF3695 PF12494.8 EGC37120.1 - 2.9 7.8 7.2 1.2 9.0 0.9 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3695) zf-RING_2 PF13639.6 EGC37121.1 - 2.2e-09 37.5 10.7 5e-09 36.3 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37121.1 - 1.5e-07 31.1 9.5 3.3e-07 30.0 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37121.1 - 1.8e-07 30.9 11.4 5.2e-07 29.4 11.4 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37121.1 - 3.8e-07 29.8 6.8 8.8e-07 28.7 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37121.1 - 0.00022 21.4 9.5 0.0012 19.1 9.5 2.3 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC37121.1 - 0.00024 21.1 5.6 0.00066 19.7 5.6 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC37121.1 - 0.00069 19.7 8.9 0.0025 17.9 8.9 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC37121.1 - 0.026 14.3 8.8 0.054 13.3 8.8 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC37121.1 - 0.034 14.2 1.0 0.075 13.1 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC37121.1 - 0.037 14.0 9.5 0.099 12.6 9.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Sigma_reg_N PF13800.6 EGC37121.1 - 0.099 12.9 1.9 0.29 11.4 1.9 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-RING_10 PF16685.5 EGC37121.1 - 0.17 12.0 3.2 0.42 10.8 3.2 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EGC37121.1 - 0.23 11.6 6.2 0.51 10.5 6.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_11 PF17123.5 EGC37121.1 - 3 7.7 8.5 7 6.5 8.5 1.7 1 0 0 1 1 1 0 RING-like zinc finger Sugar_tr PF00083.24 EGC37122.1 - 2.8e-89 300.1 37.5 1.1e-88 298.2 37.5 1.7 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.16 EGC37122.1 - 3.2e-37 128.3 31.2 4e-34 118.1 24.9 2.1 1 1 0 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.13 EGC37122.1 - 0.00011 20.8 4.1 0.00011 20.8 4.1 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-CCHC_3 PF13917.6 EGC37123.1 - 0.16 11.9 2.7 0.36 10.9 2.7 1.5 1 0 0 1 1 1 0 Zinc knuckle DUF4094 PF13334.6 EGC37123.1 - 8.8 6.8 11.6 6.3 7.3 2.4 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) TBCC PF07986.12 EGC37124.1 - 3.4e-28 97.8 6.9 6.3e-28 96.9 6.9 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EGC37124.1 - 0.0079 15.8 8.2 0.0079 15.8 8.2 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal DUF3446 PF11928.8 EGC37124.1 - 0.062 13.6 2.3 0.13 12.5 0.2 2.5 2 0 0 2 2 2 0 Early growth response N-terminal domain TBCC PF07986.12 EGC37125.1 - 4.2e-28 97.5 6.9 7.6e-28 96.7 6.9 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.11 EGC37125.1 - 0.0094 15.6 8.2 0.0094 15.6 8.2 2.0 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) C terminal DUF3446 PF11928.8 EGC37125.1 - 0.084 13.2 2.3 0.16 12.3 0.2 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain FYVE PF01363.21 EGC37126.1 - 0.00036 20.6 9.4 0.00046 20.3 7.1 2.1 2 0 0 2 2 2 1 FYVE zinc finger C1_1 PF00130.22 EGC37126.1 - 0.018 14.9 3.0 0.018 14.9 3.0 2.9 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-4CXXC_R1 PF10497.9 EGC37126.1 - 0.047 13.9 5.4 0.086 13.1 3.5 2.1 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 FYVE_2 PF02318.16 EGC37126.1 - 0.4 10.9 10.9 0.13 12.5 6.7 2.3 2 1 0 2 2 2 0 FYVE-type zinc finger IBR PF01485.21 EGC37126.1 - 0.45 10.8 13.9 4.4 7.6 6.5 3.3 2 1 1 3 3 3 0 IBR domain, a half RING-finger domain zf-CRD PF17979.1 EGC37126.1 - 2 8.5 10.5 0.94 9.6 5.6 2.6 2 1 1 3 3 3 0 Cysteine rich domain with multizinc binding regions zinc-ribbons_6 PF07191.12 EGC37126.1 - 2.7 8.0 12.4 21 5.2 0.1 3.2 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.7 EGC37126.1 - 3.9 7.5 11.2 4.5 7.3 0.5 2.8 3 0 0 3 3 3 0 Transposase zinc-ribbon domain HypA PF01155.19 EGC37126.1 - 6.3 6.9 6.8 34 4.5 0.0 3.1 2 1 0 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA C1_2 PF03107.16 EGC37126.1 - 8.5 6.8 11.6 0.068 13.5 2.6 2.2 3 0 0 3 3 3 0 C1 domain DUF2533 PF10752.9 EGC37127.1 - 0.1 13.1 0.1 20 5.7 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2533) ADH_N_2 PF16884.5 EGC37130.1 - 1.2e-23 83.1 0.0 3.1e-23 81.7 0.0 1.7 2 0 0 2 2 2 1 N-terminal domain of oxidoreductase ADH_zinc_N PF00107.26 EGC37130.1 - 2.2e-15 56.8 0.0 3.3e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC37130.1 - 1.1e-07 33.0 0.0 2.1e-07 32.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FNIP PF05725.12 EGC37133.1 - 4.8e-58 193.1 77.9 5.4e-10 39.3 0.5 10.6 5 3 8 13 13 13 11 FNIP Repeat DUF1769 PF08588.10 EGC37133.1 - 0.0018 18.4 0.5 30 4.9 0.0 5.3 6 0 0 6 6 6 2 Protein of unknown function (DUF1769) DDE_Tnp_4 PF13359.6 EGC37134.1 - 1.4e-10 41.1 0.0 2e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC37134.1 - 2.4e-05 24.1 0.1 4.2e-05 23.3 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.6 EGC37134.1 - 0.0038 16.9 0.1 0.0077 15.9 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease LEF-4 PF05098.12 EGC37135.1 - 0.02 13.7 0.0 0.022 13.6 0.0 1.1 1 0 0 1 1 1 0 Late expression factor 4 (LEF-4) FNIP PF05725.12 EGC37136.1 - 6e-45 151.2 67.7 1.3e-09 38.0 3.0 7.8 1 1 10 11 11 11 11 FNIP Repeat LRR_2 PF07723.13 EGC37136.1 - 0.42 11.3 5.4 0.57 10.9 0.0 3.4 3 0 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.12 EGC37137.1 - 7.8e-75 246.8 87.9 2e-09 37.4 2.6 15.2 5 4 10 17 17 17 17 FNIP Repeat NPR3 PF03666.13 EGC37140.1 - 5e-34 117.9 19.3 1.1e-22 80.4 5.5 2.8 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Secretin_N_2 PF07655.13 EGC37140.1 - 0.55 10.8 12.8 1 9.9 12.8 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain PEN-2 PF10251.9 EGC37141.1 - 0.049 14.1 0.8 0.088 13.2 0.8 1.4 1 0 0 1 1 1 0 Presenilin enhancer-2 subunit of gamma secretase Saf_2TM PF18303.1 EGC37141.1 - 0.15 11.7 0.2 0.2 11.2 0.2 1.1 1 0 0 1 1 1 0 SAVED-fused 2TM effector domain MKT1_C PF12246.8 EGC37142.1 - 6.7e-45 153.2 1.7 1.8e-44 151.8 1.7 1.8 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.8 EGC37142.1 - 1e-21 77.1 0.3 9.9e-21 73.9 0.0 2.8 4 0 0 4 4 4 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.18 EGC37142.1 - 0.0018 18.6 0.0 0.0055 17.0 0.0 1.9 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.17 EGC37142.1 - 0.0065 16.9 0.0 0.032 14.7 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain Gryzun PF07919.12 EGC37142.1 - 0.055 12.2 0.1 0.085 11.6 0.1 1.1 1 0 0 1 1 1 0 Gryzun, putative trafficking through Golgi Collectrin PF16959.5 EGC37142.1 - 0.068 12.9 0.2 0.3 10.9 0.1 1.9 2 0 0 2 2 2 0 Renal amino acid transporter DUF2116 PF09889.9 EGC37145.1 - 0.2 11.7 4.1 1.5 8.8 0.4 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Ac76 PF05814.11 EGC37145.1 - 0.45 10.6 5.6 0.46 10.5 4.4 1.7 1 1 1 2 2 2 0 Orf76 (Ac76) DUF2207 PF09972.9 EGC37145.1 - 0.56 8.9 3.4 0.59 8.8 3.4 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) SNARE PF05739.19 EGC37145.1 - 8.3 6.5 8.7 1.8 8.6 0.2 2.4 3 0 0 3 3 3 0 SNARE domain Peroxin-3 PF04882.12 EGC37146.1 - 4.2e-21 75.5 8.8 3.3e-19 69.2 8.8 2.1 1 1 0 1 1 1 1 Peroxin-3 TFIIB PF00382.19 EGC37147.1 - 6.4e-33 112.6 0.3 1.1e-16 60.6 0.0 2.8 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.13 EGC37147.1 - 2e-06 28.1 7.7 2e-06 28.1 7.7 2.6 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.23 EGC37147.1 - 0.00015 21.5 0.2 0.24 11.2 0.0 2.5 2 0 0 2 2 2 2 Cyclin, N-terminal domain zf-RRN7 PF11781.8 EGC37147.1 - 0.00049 19.7 1.4 0.0011 18.6 1.4 1.6 1 0 0 1 1 1 1 Zinc-finger of RNA-polymerase I-specific TFIIB, Rrn7 TF_Zn_Ribbon PF08271.12 EGC37147.1 - 0.00084 18.8 2.1 0.00084 18.8 2.1 2.0 2 0 0 2 2 1 1 TFIIB zinc-binding Cyclin_C PF02984.19 EGC37147.1 - 0.05 13.7 0.0 0.65 10.1 0.0 2.4 2 0 0 2 2 2 0 Cyclin, C-terminal domain DUF2318 PF10080.9 EGC37147.1 - 0.1 12.8 0.4 0.25 11.5 0.4 1.7 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) AAA_11 PF13086.6 EGC37147.1 - 0.54 10.0 6.9 0.97 9.2 6.9 1.5 1 0 0 1 1 1 0 AAA domain PPL5 PF18168.1 EGC37147.1 - 1.4 8.1 7.1 3.2 7.0 7.1 1.5 1 0 0 1 1 1 0 Prim-pol family 5 A2L_zn_ribbon PF08792.10 EGC37147.1 - 1.8 8.4 6.0 0.52 10.1 2.3 2.0 2 0 0 2 2 2 0 A2L zinc ribbon domain Prok-RING_1 PF14446.6 EGC37147.1 - 2.9 7.9 5.6 1 9.4 2.8 1.7 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 AAA_23 PF13476.6 EGC37147.1 - 5.2 7.5 22.7 0.027 15.0 12.2 2.3 3 0 0 3 3 3 0 AAA domain Presenilin PF01080.17 EGC37147.1 - 5.7 5.6 6.6 7.5 5.2 6.6 1.2 1 0 0 1 1 1 0 Presenilin Nudix_hydro PF18290.1 EGC37148.1 - 1.7e-28 98.4 0.0 3.9e-28 97.3 0.0 1.6 1 0 0 1 1 1 1 Nudix hydrolase domain NUDIX PF00293.28 EGC37148.1 - 3.9e-19 69.0 0.0 7.6e-19 68.0 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain Vps55 PF04133.14 EGC37150.1 - 0.11 12.4 7.8 3.6 7.6 5.8 2.4 1 1 1 2 2 2 0 Vacuolar protein sorting 55 PRA1 PF03208.19 EGC37150.1 - 0.68 9.6 6.5 0.11 12.1 2.7 1.6 2 0 0 2 2 2 0 PRA1 family protein EF-hand_1 PF00036.32 EGC37151.1 - 0.00019 20.8 0.4 0.0052 16.2 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGC37151.1 - 0.00056 19.6 0.1 0.02 14.8 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.6 EGC37151.1 - 0.0024 18.3 0.1 0.0038 17.7 0.1 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_7 PF13499.6 EGC37152.1 - 2.7e-10 40.6 6.8 1e-06 29.1 3.6 2.8 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.32 EGC37152.1 - 6.6e-10 37.8 7.6 0.0019 17.6 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.6 EGC37152.1 - 1.1e-08 34.3 6.8 0.0016 18.2 0.1 3.7 4 0 0 4 4 4 3 EF-hand domain Pox_VLTF3 PF04947.14 EGC37152.1 - 9.6e-05 22.2 0.9 0.00012 21.9 0.9 1.1 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like EF-hand_8 PF13833.6 EGC37152.1 - 0.0001 22.1 4.0 0.0042 16.9 0.1 2.8 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC37152.1 - 0.0021 17.5 0.2 0.0021 17.5 0.2 3.0 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.9 EGC37152.1 - 0.016 15.5 0.4 0.58 10.5 0.2 2.6 1 1 1 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGC37152.1 - 0.17 11.8 2.7 1 9.2 0.1 2.7 1 1 2 3 3 3 0 Caleosin related protein Glyoxalase PF00903.25 EGC37153.1 - 8.9e-16 58.2 0.7 6.7e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EGC37153.1 - 6.1e-10 39.4 0.1 2.9e-08 34.0 0.1 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.6 EGC37153.1 - 6.9e-07 29.5 0.0 0.011 16.0 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily DUF2283 PF10049.9 EGC37153.1 - 0.051 13.8 0.1 0.14 12.4 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2283) CCB1 PF12046.8 EGC37153.1 - 0.11 11.9 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 Cofactor assembly of complex C subunit B VPS13 PF16908.5 EGC37154.1 - 3.3e-65 220.2 1.7 3.3e-65 220.2 1.7 5.3 6 0 0 6 6 6 1 Vacuolar sorting-associated protein 13, N-terminal VPS13_C PF16909.5 EGC37154.1 - 1.3e-59 201.0 15.1 1.2e-58 197.8 0.9 4.1 3 0 0 3 3 3 2 Vacuolar-sorting-associated 13 protein C-terminal SHR-BD PF06650.12 EGC37154.1 - 1.1e-54 185.7 12.0 9.9e-53 179.2 0.5 3.9 3 0 0 3 3 3 2 SHR-binding domain of vacuolar-sorting associated protein 13 VPS13_mid_rpt PF16910.5 EGC37154.1 - 9.9e-52 175.7 30.2 1.5e-50 171.8 7.1 5.5 5 1 1 6 6 6 4 Repeating coiled region of VPS13 Chorein_N PF12624.7 EGC37154.1 - 1.3e-38 131.6 2.6 1.3e-38 131.6 2.6 2.9 2 0 0 2 2 2 1 N-terminal region of Chorein or VPS13 ATG_C PF09333.11 EGC37154.1 - 4.5e-11 42.9 0.1 1.5e-09 38.1 0.1 2.7 2 0 0 2 2 2 1 Autophagy-related protein C terminal domain zf-RING_2 PF13639.6 EGC37155.1 - 2.3e-09 37.4 10.5 4e-09 36.6 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC37155.1 - 2.7e-09 36.8 8.0 4.6e-09 36.0 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37155.1 - 1.1e-07 31.6 8.0 2e-07 30.8 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37155.1 - 1.1e-07 31.6 10.4 1.1e-07 31.6 10.4 2.0 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37155.1 - 1.1e-06 28.9 7.5 2.8e-06 27.5 7.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC37155.1 - 0.00033 20.6 5.1 0.00075 19.5 5.1 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC37155.1 - 0.0027 17.8 8.8 0.0077 16.4 8.5 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC37155.1 - 0.0034 17.3 9.9 0.0067 16.4 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC37155.1 - 0.0078 16.1 8.0 0.018 14.9 8.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 WBP-1 PF11669.8 EGC37155.1 - 0.094 13.4 0.1 0.094 13.4 0.1 4.9 2 1 2 4 4 3 0 WW domain-binding protein 1 zf-RING_4 PF14570.6 EGC37155.1 - 0.11 12.2 8.9 0.53 10.1 9.0 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC37155.1 - 0.12 12.6 3.8 0.34 11.1 3.8 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 PRIMA1 PF16101.5 EGC37155.1 - 0.23 11.5 1.7 0.55 10.3 1.7 1.6 1 0 0 1 1 1 0 Proline-rich membrane anchor 1 DZR PF12773.7 EGC37155.1 - 0.29 11.2 7.3 1.1 9.4 7.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EGC37155.1 - 0.4 10.8 5.2 1.2 9.2 5.2 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger EphA2_TM PF14575.6 EGC37155.1 - 1.6 9.7 0.0 1.6 9.7 0.0 3.8 3 2 0 3 3 2 0 Ephrin type-A receptor 2 transmembrane domain SapB_2 PF03489.17 EGC37156.1 - 9e-09 35.3 8.6 7.9e-07 29.1 0.1 3.2 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC37156.1 - 6.2e-06 26.1 8.3 0.001 19.0 0.0 4.3 4 2 1 5 5 5 2 Saposin-like type B, region 1 zinc_ribbon_4 PF13717.6 EGC37156.1 - 0.0011 18.8 2.3 1.3 9.0 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain Methyltransf_13 PF08421.11 EGC37156.1 - 0.3 11.4 3.9 0.51 10.6 0.2 2.4 2 0 0 2 2 2 0 Putative zinc binding domain p450 PF00067.22 EGC37157.1 - 2.9e-62 210.9 0.4 3.8e-62 210.6 0.4 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cons_hypoth698 PF03601.14 EGC37157.1 - 0.03 13.2 4.2 0.071 12.0 4.2 1.5 1 1 0 1 1 1 0 Conserved hypothetical protein 698 ETRAMP PF09716.10 EGC37157.1 - 1.1 9.4 5.0 1.9 8.6 4.4 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GNT-I PF03071.15 EGC37158.1 - 3.2e-30 105.3 6.9 8e-30 103.9 6.9 1.5 1 1 0 1 1 1 1 GNT-I family Glyco_transf_18 PF15024.6 EGC37158.1 - 0.00019 20.1 4.8 0.00019 20.1 4.8 1.5 2 0 0 2 2 2 1 Glycosyltransferase family 18 Glycos_transf_2 PF00535.26 EGC37158.1 - 0.0014 18.5 2.5 0.014 15.2 1.4 2.8 2 1 0 2 2 2 1 Glycosyl transferase family 2 DUF1338 PF07063.13 EGC37158.1 - 0.15 11.2 0.0 0.23 10.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1338) Ac76 PF05814.11 EGC37158.1 - 0.67 10.0 5.0 0.13 12.3 1.1 1.9 2 0 0 2 2 2 0 Orf76 (Ac76) C2 PF00168.30 EGC37159.1 - 3.1e-23 82.0 0.0 9.7e-23 80.4 0.0 1.9 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.17 EGC37159.1 - 7.5e-05 23.3 0.0 0.24 12.1 0.0 3.6 3 0 0 3 3 3 2 Putative heavy-metal-binding DUF4156 PF13698.6 EGC37159.1 - 0.0018 18.6 0.1 0.22 11.9 0.0 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4156) ProRS-C_1 PF09180.11 EGC37159.1 - 0.19 11.9 0.6 0.63 10.3 0.6 1.8 1 0 0 1 1 1 0 Prolyl-tRNA synthetase, C-terminal NICE-1 PF15845.5 EGC37159.1 - 0.55 11.1 10.4 2.9 8.7 0.7 2.5 2 0 0 2 2 2 0 Cysteine-rich C-terminal 1 family Peptidase_S8 PF00082.22 EGC37160.1 - 3.1e-43 148.2 2.6 5.8e-43 147.3 2.6 1.4 1 0 0 1 1 1 1 Subtilase family Androgen_recep PF02166.16 EGC37160.1 - 0.22 10.3 8.4 0.31 9.8 8.4 1.2 1 0 0 1 1 1 0 Androgen receptor DDE_1 PF03184.19 EGC37160.1 - 0.88 9.2 12.3 0.26 10.9 8.3 2.1 1 1 1 2 2 2 0 DDE superfamily endonuclease NEMP PF10225.9 EGC37160.1 - 1.3 8.6 5.0 18 4.9 0.1 2.4 2 0 0 2 2 2 0 NEMP family DivIC PF04977.15 EGC37160.1 - 3.4 7.5 17.2 18 5.2 0.3 2.5 2 0 0 2 2 2 0 Septum formation initiator Protamine_P2 PF00841.19 EGC37160.1 - 5.5 7.5 7.9 12 6.4 7.9 1.5 1 0 0 1 1 1 0 Sperm histone P2 Claudin_2 PF13903.6 EGC37161.1 - 0.0036 17.1 0.7 0.0063 16.3 0.7 1.4 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Erf4 PF10256.9 EGC37161.1 - 0.031 14.4 2.1 0.031 14.4 2.1 2.9 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF2722 PF10846.8 EGC37162.1 - 9.7e-07 28.1 5.6 1.1e-06 27.9 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) Virul_fac_BrkB PF03631.15 EGC37162.1 - 4.2e-05 23.3 1.0 7e-05 22.6 1.0 1.3 1 0 0 1 1 1 1 Virulence factor BrkB VIT1 PF01988.19 EGC37162.1 - 0.00052 20.0 0.2 0.00078 19.4 0.2 1.2 1 0 0 1 1 1 1 VIT family Erf4 PF10256.9 EGC37162.1 - 0.00079 19.5 1.7 0.002 18.2 0.3 2.2 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4191 PF13829.6 EGC37162.1 - 0.0014 18.0 3.4 0.0014 18.0 3.4 1.5 2 0 0 2 2 1 1 Domain of unknown function (DUF4191) MgtE PF01769.16 EGC37162.1 - 0.0031 17.9 4.1 0.0047 17.3 4.1 1.2 1 0 0 1 1 1 1 Divalent cation transporter TERB2 PF15101.6 EGC37162.1 - 0.13 12.3 10.9 0.17 11.9 10.9 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 DUF2126 PF09899.9 EGC37162.1 - 0.18 9.9 4.0 0.22 9.6 4.0 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Holin_BhlA PF10960.8 EGC37162.1 - 0.18 11.8 0.1 0.18 11.8 0.1 3.3 2 1 0 2 2 1 0 BhlA holin family SpoIIP PF07454.11 EGC37162.1 - 0.3 10.5 10.8 0.46 9.9 10.8 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) Band_3_cyto PF07565.13 EGC37162.1 - 0.48 10.2 5.5 0.7 9.6 5.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF702 PF05142.12 EGC37162.1 - 0.58 10.6 7.4 0.93 10.0 7.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) Peptidase_U57 PF05582.12 EGC37162.1 - 0.64 9.2 6.0 0.91 8.7 6.0 1.2 1 0 0 1 1 1 0 YabG peptidase U57 RR_TM4-6 PF06459.12 EGC37162.1 - 0.92 9.3 10.7 1.4 8.7 10.7 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Suf PF05843.14 EGC37162.1 - 2.4 8.1 15.5 0.19 11.7 10.9 1.5 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) TFIIA PF03153.13 EGC37162.1 - 3.1 7.7 29.8 0.25 11.3 24.7 1.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Saw1 PF11561.8 EGC37162.1 - 3.3 7.2 14.7 6.7 6.2 14.7 1.5 1 0 0 1 1 1 0 Single strand annealing-weakened 1 EMC3_TMCO1 PF01956.16 EGC37162.1 - 3.6 7.3 13.6 10 5.8 13.4 1.8 1 1 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like EIIBC-GUT_N PF03612.14 EGC37162.1 - 4.9 6.9 8.6 8.8 6.0 8.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus eIF-3_zeta PF05091.12 EGC37162.1 - 5.6 5.8 15.6 8.1 5.3 15.6 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Spt20 PF12090.8 EGC37162.1 - 8.1 6.0 37.5 2.4 7.7 34.6 1.5 2 0 0 2 2 1 0 Spt20 family UCH PF00443.29 EGC37165.1 - 1.8e-49 168.6 0.9 2.2e-49 168.3 0.9 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC37165.1 - 2.2e-21 76.8 0.6 3.1e-21 76.3 0.6 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.23 EGC37165.1 - 5.5e-12 45.3 0.0 1.1e-11 44.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.6 EGC37165.1 - 0.002 17.7 2.5 0.013 14.9 0.2 2.6 3 0 0 3 3 3 1 Ubiquitin-specific peptidase-like, SUMO isopeptidase Acetyltransf_1 PF00583.25 EGC37167.1 - 1.6e-15 57.3 0.1 2e-15 57.0 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC37167.1 - 5e-14 52.3 0.0 6.4e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC37167.1 - 5.4e-14 52.4 0.1 7.8e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC37167.1 - 4.6e-05 23.5 0.0 8.8e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGC37167.1 - 5e-05 23.2 0.0 9.3e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.7 EGC37167.1 - 0.0001 23.0 0.0 0.00012 22.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC37167.1 - 0.00023 21.3 0.1 0.00036 20.7 0.1 1.3 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC37167.1 - 0.0012 18.9 0.0 0.01 15.9 0.0 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.7 EGC37167.1 - 0.1 12.7 0.0 0.13 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain LIM PF00412.22 EGC37168.1 - 8.9e-26 89.9 25.0 2.9e-14 53.0 5.4 2.1 2 0 0 2 2 2 2 LIM domain DZR PF12773.7 EGC37168.1 - 0.048 13.7 20.6 1.8 8.7 6.8 3.7 1 1 2 3 3 3 0 Double zinc ribbon zf_C2HC_14 PF18574.1 EGC37168.1 - 0.15 11.8 0.2 0.15 11.8 0.2 4.0 4 0 0 4 4 4 0 C2HC Zing finger domain zinc_ribbon_9 PF14369.6 EGC37168.1 - 3.3 8.1 12.8 1.5 9.1 1.2 3.9 3 2 0 3 3 3 0 zinc-ribbon BTB_2 PF02214.22 EGC37170.1 - 6.5e-14 52.1 0.0 1.2e-13 51.2 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.31 EGC37170.1 - 0.066 13.5 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain HEPN-like_int PF18867.1 EGC37171.1 - 0.0062 16.4 0.6 0.0076 16.1 0.6 1.1 1 0 0 1 1 1 1 HEPN-like integron domain Ricin_B_lectin PF00652.22 EGC37172.1 - 3.5e-10 40.2 1.5 5e-10 39.7 0.0 2.0 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGC37172.1 - 0.0036 18.0 14.2 0.0042 17.8 0.2 4.2 3 2 2 5 5 5 3 Ricin-type beta-trefoil lectin domain-like zf-TRAF PF02176.18 EGC37173.1 - 1.1e-16 61.2 20.1 6.6e-12 45.9 9.9 4.5 3 1 2 5 5 5 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC37173.1 - 0.0002 21.2 12.2 0.0002 21.2 12.2 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37173.1 - 0.00047 19.9 13.9 0.00047 19.9 13.9 2.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC37173.1 - 0.0019 18.2 0.8 0.0019 18.2 0.8 4.1 2 1 1 4 4 4 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC37173.1 - 0.0029 18.0 38.2 0.012 16.1 12.0 3.6 1 1 3 4 4 4 2 TRAF-like zinc-finger DUF5065 PF16723.5 EGC37173.1 - 0.21 11.6 4.7 0.28 11.2 3.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5065) KASH_CCD PF14662.6 EGC37173.1 - 2 8.2 10.0 0.17 11.7 4.2 2.1 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 or KASH Actin PF00022.19 EGC37174.1 - 5e-75 252.6 0.0 1.8e-36 125.7 0.0 2.0 1 1 1 2 2 2 2 Actin MreB_Mbl PF06723.13 EGC37174.1 - 0.049 12.5 0.0 0.2 10.4 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein PhoLip_ATPase_C PF16212.5 EGC37175.1 - 1.3e-92 310.1 24.4 1.3e-92 310.1 24.4 2.7 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC37175.1 - 1.5e-29 101.5 4.9 1.5e-29 101.5 4.9 2.7 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGC37175.1 - 8.7e-17 61.2 0.1 8.7e-17 61.2 0.1 2.0 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGC37175.1 - 2.1e-12 46.9 0.0 2.6e-11 43.4 0.0 2.4 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC37175.1 - 2.6e-07 31.1 1.9 0.0086 16.4 0.7 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.12 EGC37175.1 - 0.0084 15.9 0.1 0.0084 15.9 0.1 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase DUF2149 PF09919.9 EGC37175.1 - 1.1 9.6 2.9 8.9 6.7 0.1 3.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2149) Peptidase_M24 PF00557.24 EGC37176.1 - 4e-54 183.5 0.2 5.6e-54 183.0 0.2 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGC37176.1 - 1.5e-25 89.3 0.0 2.8e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.7 EGC37176.1 - 0.0018 18.3 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3793) EGF_2 PF07974.13 EGC37177.1 - 0.0033 17.7 9.7 0.0075 16.6 9.7 1.6 1 0 0 1 1 1 1 EGF-like domain DUF1735 PF08522.10 EGC37177.1 - 0.015 15.9 3.2 0.089 13.4 3.2 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1735) TMEM100 PF16311.5 EGC37177.1 - 0.04 13.5 0.7 0.11 12.0 0.6 1.8 2 0 0 2 2 2 0 Transmembrane protein 100 MacB_PCD PF12704.7 EGC37177.1 - 0.13 12.6 1.0 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 MacB-like periplasmic core domain bZIP_1 PF00170.21 EGC37178.1 - 1.9e-13 50.3 10.2 6e-13 48.7 10.2 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.15 EGC37178.1 - 5.4e-08 32.8 6.4 5.4e-08 32.8 6.4 3.5 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGC37178.1 - 0.0013 19.3 6.3 0.0013 19.3 6.3 3.2 3 0 0 3 3 3 1 bZIP Maf transcription factor Babuvirus_MP PF07234.11 EGC37180.1 - 0.0098 16.0 2.4 0.015 15.5 2.3 1.5 1 1 0 1 1 1 1 Movement and RNA silencing protein DUF805 PF05656.14 EGC37180.1 - 0.012 16.0 0.2 0.015 15.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF805) Vma12 PF11712.8 EGC37180.1 - 0.13 12.3 1.6 0.22 11.6 1.6 1.6 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3043 PF11241.8 EGC37180.1 - 4.3 7.3 5.8 6.2 6.8 5.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) ABC2_membrane PF01061.24 EGC37181.1 - 7.5e-39 133.3 23.3 1.2e-38 132.7 23.3 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC37181.1 - 3.1e-28 99.0 0.1 3.1e-28 99.0 0.1 2.1 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.7 EGC37181.1 - 5.1e-09 35.7 7.3 5.1e-09 35.7 7.3 2.3 2 0 0 2 2 1 1 ABC-2 family transporter protein AAA_21 PF13304.6 EGC37181.1 - 1.7e-07 31.4 5.5 0.001 18.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC37181.1 - 7e-06 26.5 0.0 1.2e-05 25.7 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain PDR_CDR PF06422.12 EGC37181.1 - 0.00064 19.6 0.1 0.0017 18.3 0.1 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_22 PF13401.6 EGC37181.1 - 0.00066 20.0 0.0 0.0018 18.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC37181.1 - 0.00083 19.3 0.3 0.0018 18.2 0.3 1.7 1 0 0 1 1 1 1 RsgA GTPase Thymidylate_kin PF02223.17 EGC37181.1 - 0.0015 18.2 0.0 0.0041 16.8 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase AAA_29 PF13555.6 EGC37181.1 - 0.002 17.8 0.1 0.0049 16.6 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_35 PF14516.6 EGC37181.1 - 0.0043 15.9 0.1 0.0063 15.4 0.1 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_33 PF13671.6 EGC37181.1 - 0.005 17.0 0.0 0.015 15.5 0.0 1.8 2 0 0 2 2 1 1 AAA domain T2SSE PF00437.20 EGC37181.1 - 0.011 14.8 0.2 0.025 13.6 0.2 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_18 PF13238.6 EGC37181.1 - 0.016 15.7 0.0 0.016 15.7 0.0 2.6 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.6 EGC37181.1 - 0.024 14.7 2.1 0.033 14.2 0.0 2.4 2 0 0 2 2 1 0 AAA domain AAA PF00004.29 EGC37181.1 - 0.027 14.9 0.0 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGC37181.1 - 0.035 13.7 0.0 0.07 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGC37181.1 - 0.052 13.5 0.0 7.1 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase APS_kinase PF01583.20 EGC37181.1 - 0.088 12.7 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase TsaE PF02367.17 EGC37181.1 - 0.11 12.5 0.1 0.22 11.5 0.1 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EGC37181.1 - 0.14 11.9 0.0 0.38 10.5 0.0 1.7 1 0 0 1 1 1 0 Cytidylate kinase AAA_28 PF13521.6 EGC37181.1 - 0.14 12.4 0.1 0.27 11.5 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC37181.1 - 0.17 11.6 0.0 0.32 10.7 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein MeaB PF03308.16 EGC37181.1 - 0.83 8.6 3.4 0.21 10.5 0.3 1.5 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB ABC2_membrane_2 PF12679.7 EGC37181.1 - 6.4 6.0 9.4 0.18 11.1 3.4 1.5 2 0 0 2 2 1 0 ABC-2 family transporter protein Nup160 PF11715.8 EGC37182.1 - 7.1e-25 87.6 18.9 1.6e-24 86.5 18.9 1.6 1 0 0 1 1 1 1 Nucleoporin Nup120/160 CcmE PF03100.15 EGC37182.1 - 6.2e-14 52.1 0.4 1.8e-13 50.6 0.4 1.8 1 0 0 1 1 1 1 CcmE PLAC8 PF04749.17 EGC37183.1 - 0.31 12.1 1.2 0.39 11.7 0.4 1.8 2 1 0 2 2 2 0 PLAC8 family AAA_12 PF13087.6 EGC37184.1 - 1.6e-53 181.3 0.7 1.6e-53 181.3 0.7 3.1 4 0 0 4 4 4 1 AAA domain AAA_11 PF13086.6 EGC37184.1 - 2.2e-32 112.9 0.5 2.4e-20 73.4 0.0 4.7 4 2 1 5 5 4 2 AAA domain AAA_19 PF13245.6 EGC37184.1 - 1.3e-08 35.3 0.0 4.2e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC37184.1 - 2.4e-07 30.7 0.0 5e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain NTP_transf_2 PF01909.23 EGC37184.1 - 2.1e-05 24.7 0.0 2.1e-05 24.7 0.0 3.6 4 0 0 4 4 4 1 Nucleotidyltransferase domain Viral_helicase1 PF01443.18 EGC37184.1 - 3.3e-05 23.7 0.0 1 9.1 0.0 3.7 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase PAP_assoc PF03828.19 EGC37184.1 - 7.2e-05 22.9 0.3 0.00026 21.1 0.3 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase AAA_22 PF13401.6 EGC37184.1 - 0.00014 22.1 0.0 0.00066 20.0 0.0 2.2 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGC37184.1 - 0.0041 17.1 0.0 0.0041 17.1 0.0 4.3 4 0 0 4 4 4 1 Type III restriction enzyme, res subunit DUF4209 PF13910.6 EGC37184.1 - 0.011 15.9 0.2 0.064 13.5 0.2 2.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4209) NEMO PF11577.8 EGC37184.1 - 0.02 14.9 2.7 0.37 10.8 0.1 3.8 3 0 0 3 3 3 0 NF-kappa-B essential modulator NEMO PhoH PF02562.16 EGC37184.1 - 0.039 13.4 0.1 0.21 11.0 0.1 2.2 1 1 0 1 1 1 0 PhoH-like protein T2SSE PF00437.20 EGC37184.1 - 0.045 12.8 0.0 0.094 11.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.6 EGC37184.1 - 0.11 12.8 0.0 0.31 11.4 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain Chromo PF00385.24 EGC37186.1 - 8.8e-07 28.7 0.2 1.2e-06 28.4 0.2 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain PAP2 PF01569.21 EGC37187.1 - 1.5e-20 73.3 4.4 1.5e-20 73.3 4.4 1.8 2 0 0 2 2 2 1 PAP2 superfamily DUF2207 PF09972.9 EGC37187.1 - 0.0005 19.0 2.0 0.0097 14.7 0.1 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2207) EOS1 PF12326.8 EGC37187.1 - 0.93 9.4 3.4 0.43 10.5 0.6 1.9 2 0 0 2 2 2 0 N-glycosylation protein Acetyltransf_4 PF13420.7 EGC37188.1 - 8.6e-23 81.2 0.1 1e-22 80.9 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC37188.1 - 3.5e-12 46.6 0.1 4.4e-12 46.3 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.7 EGC37188.1 - 5e-06 27.2 0.0 6.3e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC37188.1 - 2.2e-05 24.8 0.1 3.3e-05 24.2 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC37188.1 - 6.1e-05 22.9 0.0 9.5e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGC37188.1 - 0.00015 21.7 0.0 0.00019 21.3 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.7 EGC37188.1 - 0.042 13.4 0.0 0.083 12.4 0.0 1.4 1 1 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 EGC37188.1 - 0.12 11.9 1.2 0.2 11.1 1.1 1.6 1 1 0 1 1 1 0 Putative acetyl-transferase AAA PF00004.29 EGC37189.1 - 4e-52 176.1 2.2 1.7e-34 119.1 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC37189.1 - 1.4e-13 50.4 0.1 6.3e-09 35.5 0.1 2.4 2 0 0 2 2 2 2 AAA+ lid domain AAA_22 PF13401.6 EGC37189.1 - 5.1e-11 43.0 1.0 0.0001 22.6 0.0 5.5 4 2 1 5 5 5 2 AAA domain AAA_14 PF13173.6 EGC37189.1 - 2e-10 40.8 1.9 0.00021 21.3 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.6 EGC37189.1 - 9.6e-10 39.1 0.0 0.0064 16.9 0.0 3.3 2 1 0 3 3 3 2 AAA ATPase domain AAA_2 PF07724.14 EGC37189.1 - 1.1e-08 35.3 0.3 0.0017 18.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) TIP49 PF06068.13 EGC37189.1 - 3.4e-07 29.8 0.2 0.0001 21.6 0.1 2.8 2 0 0 2 2 2 1 TIP49 P-loop domain RuvB_N PF05496.12 EGC37189.1 - 6.2e-07 29.3 0.0 0.00036 20.3 0.0 3.0 2 0 0 2 2 2 1 Holliday junction DNA helicase RuvB P-loop domain AAA_7 PF12775.7 EGC37189.1 - 1.4e-06 28.0 0.0 0.0084 15.6 0.0 2.7 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_33 PF13671.6 EGC37189.1 - 2.4e-06 27.8 0.0 0.0014 18.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGC37189.1 - 7.8e-06 25.7 0.0 0.00058 19.6 0.0 2.4 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_29 PF13555.6 EGC37189.1 - 1.1e-05 25.1 0.2 0.041 13.6 0.0 3.4 3 0 0 3 3 3 1 P-loop containing region of AAA domain AAA_18 PF13238.6 EGC37189.1 - 1.4e-05 25.7 2.0 0.2 12.2 0.0 3.6 3 1 0 3 3 2 2 AAA domain ABC_tran PF00005.27 EGC37189.1 - 2e-05 25.1 3.1 0.012 16.1 0.1 3.0 3 0 0 3 3 2 2 ABC transporter AAA_5 PF07728.14 EGC37189.1 - 2.4e-05 24.4 0.1 0.0022 18.0 0.0 3.2 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_28 PF13521.6 EGC37189.1 - 2.4e-05 24.7 0.0 0.16 12.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGC37189.1 - 3e-05 24.4 0.9 0.32 11.4 0.0 4.0 4 0 0 4 4 4 2 RNA helicase Mg_chelatase PF01078.21 EGC37189.1 - 3.2e-05 23.4 0.1 0.0022 17.4 0.1 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGC37189.1 - 6.4e-05 22.8 0.2 0.096 12.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain Rad17 PF03215.15 EGC37189.1 - 9.2e-05 22.4 2.3 0.0074 16.2 0.2 3.3 3 2 0 3 3 2 1 Rad17 P-loop domain DUF815 PF05673.13 EGC37189.1 - 9.5e-05 21.7 0.1 0.037 13.2 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.12 EGC37189.1 - 0.00016 21.7 1.3 0.07 13.0 0.0 3.7 3 2 2 5 5 4 1 NACHT domain Zeta_toxin PF06414.12 EGC37189.1 - 0.00016 21.0 0.0 0.64 9.3 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin TsaE PF02367.17 EGC37189.1 - 0.00024 21.1 0.1 0.24 11.4 0.0 2.7 3 0 0 3 3 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE T2SSE PF00437.20 EGC37189.1 - 0.00041 19.5 0.0 0.38 9.8 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.6 EGC37189.1 - 0.00067 19.3 0.7 0.78 9.3 0.1 3.3 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 EGC37189.1 - 0.00071 19.0 0.1 5.6 6.3 0.0 3.8 3 0 0 3 3 3 0 Bacterial TniB protein AAA_17 PF13207.6 EGC37189.1 - 0.0018 18.7 0.0 0.66 10.4 0.0 2.8 2 0 0 2 2 2 1 AAA domain Sigma54_activat PF00158.26 EGC37189.1 - 0.0024 17.6 0.1 0.0091 15.7 0.1 2.1 2 1 0 2 2 1 1 Sigma-54 interaction domain PPV_E1_C PF00519.17 EGC37189.1 - 0.0072 15.2 0.1 0.34 9.7 0.0 2.3 2 0 0 2 2 2 1 Papillomavirus helicase Bac_DnaA PF00308.18 EGC37189.1 - 0.0082 16.0 3.6 0.015 15.1 0.2 3.0 2 2 0 2 2 2 1 Bacterial dnaA protein Parvo_NS1 PF01057.17 EGC37189.1 - 0.0099 15.0 0.2 0.34 9.9 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_11 PF13086.6 EGC37189.1 - 0.012 15.5 0.0 0.12 12.2 0.0 2.4 2 0 0 2 2 2 0 AAA domain Cytidylate_kin PF02224.18 EGC37189.1 - 0.014 15.2 0.0 6 6.5 0.0 2.5 2 0 0 2 2 2 0 Cytidylate kinase Vps4_C PF09336.10 EGC37189.1 - 0.019 14.9 0.0 0.073 13.1 0.0 2.0 1 0 0 1 1 1 0 Vps4 C terminal oligomerisation domain PRNT PF15174.6 EGC37189.1 - 0.03 14.3 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Prion-related protein testis-specific PhoH PF02562.16 EGC37189.1 - 0.038 13.5 0.0 0.099 12.1 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein Guanylate_kin PF00625.21 EGC37189.1 - 0.053 13.2 0.1 7.7 6.2 0.0 3.3 3 0 0 3 3 3 0 Guanylate kinase CPT PF07931.12 EGC37189.1 - 0.053 13.4 0.0 6.2 6.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AAA_30 PF13604.6 EGC37189.1 - 0.07 12.8 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGC37189.1 - 0.1 11.9 3.8 0.78 9.0 0.3 3.8 3 1 0 3 3 3 0 KaiC AAA_3 PF07726.11 EGC37189.1 - 0.11 12.3 0.0 0.65 9.9 0.0 2.4 3 0 0 3 3 1 0 ATPase family associated with various cellular activities (AAA) Zot PF05707.12 EGC37189.1 - 0.13 11.9 0.1 26 4.4 0.0 3.1 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) AAA_19 PF13245.6 EGC37189.1 - 0.17 12.2 0.1 2.8 8.3 0.1 2.6 3 0 0 3 3 2 0 AAA domain WD40 PF00400.32 EGC37192.1 - 3.3e-06 27.7 5.6 3 8.9 0.1 5.6 5 2 0 5 5 5 3 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37192.1 - 0.0027 18.0 0.1 11 6.4 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain DNA_pol_E_B PF04042.16 EGC37193.1 - 2.8e-45 154.3 0.7 5.3e-45 153.4 0.7 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.8 EGC37193.1 - 1.1e-07 32.1 0.8 3.2e-07 30.5 0.8 1.9 1 0 0 1 1 1 1 DNA polymerases epsilon N terminal Pkinase_Tyr PF07714.17 EGC37194.1 - 3.2e-51 174.1 0.0 4.6e-51 173.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC37194.1 - 2.8e-47 161.3 0.0 4.8e-47 160.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.29 EGC37195.1 - 3.3e-48 163.8 0.0 2e-47 161.2 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC37195.1 - 1.6e-31 108.9 0.0 2.8e-30 104.9 0.0 2.7 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC37195.1 - 4.5e-05 23.5 0.0 0.00011 22.3 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit UTP25 PF06862.12 EGC37195.1 - 0.0052 15.6 0.0 0.03 13.1 0.0 1.9 1 1 0 1 1 1 1 Utp25, U3 small nucleolar RNA-associated SSU processome protein 25 Kelch_1 PF01344.25 EGC37196.1 - 1.6e-51 171.7 4.9 7.4e-10 38.3 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC37196.1 - 6.8e-43 144.5 20.7 3.3e-08 33.4 0.5 6.1 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC37196.1 - 1.7e-41 138.7 13.7 5.6e-06 26.1 1.1 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.6 EGC37196.1 - 7e-40 134.1 15.0 6.8e-08 32.5 0.0 6.1 3 1 3 6 6 6 6 Kelch motif Kelch_5 PF13854.6 EGC37196.1 - 3.2e-39 132.3 9.5 4.5e-08 32.9 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_3 PF13415.6 EGC37196.1 - 3e-37 126.2 14.0 1.2e-08 35.0 0.0 6.4 7 0 0 7 7 7 6 Galactose oxidase, central domain UPF0542 PF15086.6 EGC37197.1 - 0.13 12.2 1.5 10 6.2 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 Secretin_N_2 PF07655.13 EGC37197.1 - 1.1 9.8 9.3 1.8 9.1 9.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain FKBP_C PF00254.28 EGC37198.1 - 1.3e-19 70.3 0.0 2.4e-19 69.4 0.0 1.5 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_1 PF00515.28 EGC37198.1 - 2e-10 40.0 1.0 0.0065 16.2 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC37198.1 - 5.2e-10 38.7 0.7 0.0027 17.7 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37198.1 - 1.9e-06 27.6 6.8 0.007 16.5 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC37198.1 - 0.00028 21.1 0.1 0.0013 19.0 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC37198.1 - 0.0018 18.2 0.1 0.23 11.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC37198.1 - 0.014 16.0 0.4 9.1 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.6 EGC37198.1 - 0.015 15.7 0.4 1.2 9.7 0.0 3.3 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC37198.1 - 0.023 15.2 0.1 0.49 10.9 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.6 EGC37198.1 - 0.073 12.8 0.7 6.6 6.5 0.1 2.8 2 0 0 2 2 2 0 TPR repeat ANAPC3 PF12895.7 EGC37198.1 - 1.2 9.4 3.7 1.9 8.8 0.4 2.6 2 2 1 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Ubiquitin_2 PF14560.6 EGC37199.1 - 7.9e-27 93.5 0.3 1.5e-26 92.7 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.25 EGC37199.1 - 8e-24 83.5 0.2 1.3e-23 82.7 0.2 1.4 1 0 0 1 1 1 1 CAP-Gly domain Mito_carr PF00153.27 EGC37201.1 - 1.4e-65 217.3 2.1 1.8e-21 75.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Serine_protease PF18405.1 EGC37201.1 - 0.064 12.4 0.1 0.65 9.1 0.0 2.3 2 0 0 2 2 2 0 Gammaproteobacterial serine protease Citrate_synt PF00285.21 EGC37202.1 - 2.1e-24 86.3 0.0 6.9e-20 71.4 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase, C-terminal domain Ligase_CoA PF00549.19 EGC37202.1 - 4.9e-10 39.4 0.1 2.7e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase CoA_binding PF02629.19 EGC37202.1 - 0.00052 20.7 0.0 0.0012 19.5 0.0 1.7 1 0 0 1 1 1 1 CoA binding domain Succ_CoA_lig PF13607.6 EGC37202.1 - 0.00057 19.7 0.0 0.012 15.4 0.0 2.5 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain SapB_1 PF05184.15 EGC37203.1 - 3.3e-05 23.8 0.4 7.9e-05 22.6 0.4 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 SecY PF00344.20 EGC37203.1 - 0.097 11.9 0.0 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 SecY translocase RRM_1 PF00076.22 EGC37204.1 - 8.2e-18 64.0 0.1 1.2e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC37204.1 - 0.00059 19.8 0.0 0.00099 19.1 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif TSC22 PF01166.18 EGC37205.1 - 0.039 14.2 3.1 0.039 14.2 3.1 7.6 3 2 5 8 8 8 0 TSC-22/dip/bun family ERM PF00769.19 EGC37205.1 - 2.9 7.6 61.0 0.16 11.8 11.0 3.1 2 1 1 3 3 3 0 Ezrin/radixin/moesin family ApoO PF09769.9 EGC37205.1 - 7.9 6.4 10.7 4.1 7.4 0.9 3.7 3 1 1 4 4 4 0 Apolipoprotein O Tropomyosin_1 PF12718.7 EGC37206.1 - 0.0013 18.8 22.1 0.0013 18.8 22.1 4.3 3 1 1 4 4 4 1 Tropomyosin like CENP-F_leu_zip PF10473.9 EGC37206.1 - 0.0039 17.2 29.0 0.0039 17.2 29.0 4.6 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.13 EGC37206.1 - 0.017 15.0 1.7 0.017 15.0 1.7 5.5 4 1 2 6 6 6 0 Sec20 MbeD_MobD PF04899.12 EGC37206.1 - 0.11 12.6 8.4 5.3 7.2 0.1 4.8 4 1 2 6 6 6 0 MbeD/MobD like DUF5129 PF17173.4 EGC37206.1 - 0.36 9.9 11.4 0.19 10.8 2.2 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF5129) ATG16 PF08614.11 EGC37206.1 - 0.44 10.8 59.9 0.46 10.7 10.6 5.3 2 2 3 5 5 5 0 Autophagy protein 16 (ATG16) XhlA PF10779.9 EGC37206.1 - 0.48 10.7 0.1 0.48 10.7 0.1 7.1 5 1 4 9 9 9 0 Haemolysin XhlA HOOK PF05622.12 EGC37206.1 - 0.51 8.4 55.6 0.1 10.8 19.6 3.2 2 1 1 3 3 3 0 HOOK protein HrpB7 PF09486.10 EGC37206.1 - 1.8 8.9 11.9 9.5 6.6 4.4 3.3 3 1 0 3 3 3 0 Bacterial type III secretion protein (HrpB7) DUF4201 PF13870.6 EGC37206.1 - 5.5 6.7 51.9 12 5.6 22.5 4.7 2 2 2 4 4 4 0 Domain of unknown function (DUF4201) ABC_tran_CTD PF16326.5 EGC37206.1 - 8.6 6.7 45.7 3.9 7.8 4.1 5.3 3 2 2 5 5 5 0 ABC transporter C-terminal domain DUF4419 PF14388.6 EGC37207.1 - 9e-07 28.6 0.0 0.0005 19.6 0.0 2.4 1 1 1 2 2 2 2 Domain of unknown function (DUF4419) Arf PF00025.21 EGC37208.1 - 4.6e-24 84.8 0.0 5.7e-24 84.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGC37208.1 - 4.9e-06 26.1 0.6 1.5e-05 24.5 0.6 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC37208.1 - 1.3e-05 25.2 0.3 0.00015 21.9 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGC37208.1 - 0.00063 20.0 0.2 0.0068 16.6 0.2 2.1 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MobB PF03205.14 EGC37208.1 - 0.0018 18.2 0.4 0.0045 16.9 0.2 1.7 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.19 EGC37208.1 - 0.0068 16.0 1.4 0.15 11.7 0.1 2.1 1 1 1 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ATPase_2 PF01637.18 EGC37208.1 - 0.01 15.8 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 0 ATPase domain predominantly from Archaea Ras PF00071.22 EGC37208.1 - 0.024 14.3 0.3 0.2 11.2 0.3 2.0 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.6 EGC37208.1 - 0.066 13.3 0.1 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Lon_C PF05362.13 EGC37209.1 - 9.7e-61 204.9 0.0 1.8e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.29 EGC37209.1 - 1.3e-24 87.1 0.1 6.7e-24 84.8 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.14 EGC37209.1 - 5.1e-10 39.7 0.0 1.4e-09 38.3 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.14 EGC37209.1 - 1.5e-08 34.7 0.0 3e-08 33.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) LON_substr_bdg PF02190.16 EGC37209.1 - 1.4e-07 31.6 1.4 3.5e-07 30.3 0.7 2.2 2 0 0 2 2 1 1 ATP-dependent protease La (LON) substrate-binding domain ChlI PF13541.6 EGC37209.1 - 1.4e-07 31.3 0.1 4.1e-07 29.9 0.0 1.8 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_PrkA PF08298.11 EGC37209.1 - 3e-05 23.1 0.0 8e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.6 EGC37209.1 - 0.00056 20.2 0.3 0.052 13.8 0.3 2.6 1 1 0 1 1 1 1 AAA domain AAA_3 PF07726.11 EGC37209.1 - 0.00074 19.4 0.0 0.0019 18.1 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC37209.1 - 0.002 18.5 0.7 0.014 15.7 0.0 2.4 2 1 1 3 3 2 1 AAA ATPase domain RuvB_N PF05496.12 EGC37209.1 - 0.0023 17.7 0.0 0.0067 16.2 0.0 1.8 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain RNA_helicase PF00910.22 EGC37209.1 - 0.0031 17.9 0.0 0.009 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase MCM PF00493.23 EGC37209.1 - 0.0047 16.0 0.0 0.01 14.9 0.0 1.5 1 0 0 1 1 1 1 MCM P-loop domain Parvo_NS1 PF01057.17 EGC37209.1 - 0.0051 16.0 0.0 0.015 14.4 0.0 1.7 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 TIP49 PF06068.13 EGC37209.1 - 0.0054 16.0 0.1 0.021 14.1 0.1 2.0 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_7 PF12775.7 EGC37209.1 - 0.0061 16.1 0.5 0.036 13.6 0.0 2.4 3 0 0 3 3 2 1 P-loop containing dynein motor region Nnf1 PF03980.14 EGC37209.1 - 0.0065 16.8 6.8 0.018 15.4 6.8 1.7 1 0 0 1 1 1 1 Nnf1 AAA_14 PF13173.6 EGC37209.1 - 0.0091 16.0 0.0 0.0091 16.0 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_15 PF13175.6 EGC37209.1 - 0.011 15.5 0.4 0.011 15.5 0.4 3.3 2 1 0 2 2 1 0 AAA ATPase domain AAA_19 PF13245.6 EGC37209.1 - 0.012 15.9 0.0 0.058 13.7 0.0 2.1 2 0 0 2 2 1 0 AAA domain MIEAP PF16026.5 EGC37209.1 - 0.017 15.4 0.1 0.083 13.1 0.1 2.1 1 1 1 2 2 1 0 Mitochondria-eating protein AAA_18 PF13238.6 EGC37209.1 - 0.017 15.7 2.0 0.032 14.8 0.1 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGC37209.1 - 0.031 14.0 0.0 0.067 12.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein CbiA PF01656.23 EGC37209.1 - 0.032 14.3 0.3 14 5.8 0.0 3.1 3 0 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.6 EGC37209.1 - 0.036 13.8 0.0 0.1 12.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain RsgA_GTPase PF03193.16 EGC37209.1 - 0.037 13.9 0.0 0.12 12.3 0.0 1.8 1 0 0 1 1 1 0 RsgA GTPase ABC_tran PF00005.27 EGC37209.1 - 0.062 13.8 2.9 0.1 13.1 0.1 2.5 2 0 0 2 2 2 0 ABC transporter ATP-synt_ab PF00006.25 EGC37209.1 - 0.067 12.8 0.0 0.098 12.3 0.0 1.3 1 0 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_28 PF13521.6 EGC37209.1 - 0.067 13.4 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.21 EGC37209.1 - 0.07 12.5 0.0 0.21 11.0 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGC37209.1 - 0.072 13.0 0.0 0.31 10.9 0.0 2.0 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.6 EGC37209.1 - 0.08 13.1 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGC37209.1 - 0.11 12.4 2.0 0.32 10.9 0.1 2.6 2 1 1 3 3 2 0 NTPase AAA_24 PF13479.6 EGC37209.1 - 0.41 10.3 3.6 0.18 11.5 0.1 2.2 3 0 0 3 3 2 0 AAA domain ResIII PF04851.15 EGC37209.1 - 0.45 10.5 0.0 0.45 10.5 0.0 3.4 3 2 0 3 3 3 0 Type III restriction enzyme, res subunit Pkinase_Tyr PF07714.17 EGC37210.1 - 6.5e-57 192.8 0.0 9.8e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC37210.1 - 5.4e-55 186.6 0.0 9.6e-55 185.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC37210.1 - 9.7e-07 27.9 0.0 9.7e-07 27.9 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase DUF4570 PF15134.6 EGC37210.1 - 0.1 12.6 1.2 0.22 11.6 1.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4570) SKG6 PF08693.10 EGC37210.1 - 0.67 9.4 5.9 1.6 8.2 5.9 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Adipogenin PF15202.6 EGC37210.1 - 1.9 8.6 4.9 4.3 7.4 4.9 1.6 1 0 0 1 1 1 0 Adipogenin GST_N PF02798.20 EGC37212.1 - 3.3e-17 62.6 0.1 5.9e-17 61.8 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC37212.1 - 8.4e-17 61.4 0.1 1.3e-16 60.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC37212.1 - 3.2e-15 56.2 0.0 5.7e-15 55.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.6 EGC37212.1 - 8.2e-08 32.3 0.0 1.6e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC37212.1 - 0.0013 18.9 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.24 EGC37212.1 - 0.0059 16.8 0.0 0.011 16.0 0.0 1.5 1 0 0 1 1 1 1 Glutaredoxin Methyltransf_23 PF13489.6 EGC37214.1 - 8.9e-06 25.6 0.0 2.1e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37214.1 - 5.6e-05 23.8 0.0 0.00017 22.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37214.1 - 0.0002 21.2 0.0 0.00041 20.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGC37214.1 - 0.00021 20.7 4.1 0.00064 19.2 0.0 2.7 4 0 0 4 4 4 1 Tellurite resistance protein TehB Rhodanese PF00581.20 EGC37214.1 - 0.0045 17.5 0.0 0.0095 16.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_11 PF08241.12 EGC37214.1 - 0.0054 17.3 0.0 0.016 15.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.11 EGC37214.1 - 0.05 13.3 0.0 0.79 9.3 0.0 2.3 2 1 1 3 3 3 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.12 EGC37214.1 - 0.31 11.8 5.0 2.2 9.1 0.2 3.5 2 1 0 2 2 2 0 Methyltransferase domain Diphthami_syn_2 PF01902.17 EGC37215.1 - 1.4e-37 129.3 0.0 4.5e-37 127.7 0.0 1.6 1 1 0 1 1 1 1 Diphthamide synthase P22_AR_C PF10548.9 EGC37215.1 - 0.095 12.9 0.0 0.23 11.6 0.0 1.7 1 0 0 1 1 1 0 P22AR C-terminal domain SPC12 PF06645.13 EGC37216.1 - 1.5e-27 95.4 2.2 1.7e-27 95.3 2.2 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) LtrA PF06772.11 EGC37216.1 - 0.0013 18.1 0.1 0.0013 18.0 0.1 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) ArsP_1 PF03773.13 EGC37216.1 - 0.021 14.0 0.9 0.024 13.8 0.9 1.1 1 0 0 1 1 1 0 Predicted permease DUF1449 PF07290.11 EGC37216.1 - 0.053 13.1 0.3 0.063 12.9 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) TraB PF01963.17 EGC37218.1 - 4.9e-17 62.7 0.1 3.7e-08 33.6 0.0 2.4 2 0 0 2 2 2 2 TraB family SapB_1 PF05184.15 EGC37218.1 - 5.2 7.2 5.4 23 5.1 0.8 3.1 1 1 1 2 2 2 0 Saposin-like type B, region 1 Acatn PF13000.7 EGC37219.1 - 6.8e-139 463.9 34.6 6.4e-111 371.5 20.0 2.5 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Methyltransf_12 PF08242.12 EGC37220.1 - 2e-08 34.9 7.0 2e-06 28.4 0.0 3.2 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_23 PF13489.6 EGC37220.1 - 8.2e-08 32.3 0.0 1.7e-07 31.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37220.1 - 1.7e-07 31.8 0.0 5.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37220.1 - 6.7e-06 26.0 0.7 2e-05 24.4 0.0 2.1 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC37220.1 - 6.4e-05 23.5 0.0 0.00018 22.1 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Menin PF05053.13 EGC37220.1 - 5.4 5.3 10.3 8.1 4.7 10.3 1.3 1 0 0 1 1 1 0 Menin EMC3_TMCO1 PF01956.16 EGC37221.1 - 1.9e-52 177.4 2.6 1.9e-52 177.4 2.6 1.8 2 0 0 2 2 2 1 Integral membrane protein EMC3/TMCO1-like Citrate_bind PF16114.5 EGC37222.1 - 5.6e-84 280.1 0.0 7.7e-84 279.6 0.0 1.2 1 0 0 1 1 1 1 ATP citrate lyase citrate-binding ATP-grasp_2 PF08442.10 EGC37222.1 - 6.4e-16 58.5 0.0 1e-15 57.9 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp domain zf-TFIIB PF13453.6 EGC37222.1 - 0.071 12.5 0.2 0.16 11.3 0.2 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger WD40 PF00400.32 EGC37223.1 - 1.7e-30 104.6 8.1 5.1e-08 33.4 0.4 6.3 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37223.1 - 2.4e-18 66.2 0.8 2.9e-05 24.3 0.0 5.5 3 2 2 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain LisH_TPL PF17814.1 EGC37223.1 - 3.3e-13 49.0 0.3 6.5e-13 48.1 0.3 1.5 1 0 0 1 1 1 1 LisH-like dimerisation domain Ge1_WD40 PF16529.5 EGC37223.1 - 4.5e-10 39.0 4.5 1.5e-05 24.2 0.1 3.8 1 1 3 4 4 4 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC37223.1 - 7.7e-09 34.7 4.0 0.0089 14.7 1.3 4.4 1 1 2 4 4 4 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.11 EGC37223.1 - 1.1e-05 24.4 7.5 0.15 10.8 1.4 3.2 2 1 1 3 3 3 3 Nup133 N terminal like Cytochrom_D1 PF02239.16 EGC37223.1 - 0.0044 15.6 0.0 0.84 8.1 0.0 3.1 3 0 0 3 3 3 1 Cytochrome D1 heme domain Lactonase PF10282.9 EGC37223.1 - 0.01 15.1 0.2 0.79 8.9 0.1 2.4 2 0 0 2 2 2 0 Lactonase, 7-bladed beta-propeller DUF4784 PF16023.5 EGC37223.1 - 0.17 10.8 1.2 0.61 9.0 0.5 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4784) Lactamase_B PF00753.27 EGC37224.1 - 3e-09 37.2 2.8 6.9e-09 36.0 2.8 1.6 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC37224.1 - 1.8e-06 27.6 0.2 2.8e-06 27.0 0.2 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain BLACT_WH PF17778.1 EGC37224.1 - 1.9e-06 27.8 0.0 4.2e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Beta-lactamase associated winged helix domain RCC1 PF00415.18 EGC37225.1 - 2.7e-72 239.2 0.2 1.2e-13 51.5 0.2 7.9 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC37225.1 - 1.2e-46 155.6 18.6 3.5e-10 39.4 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.6 EGC37225.1 - 0.054 13.5 9.6 2.9 8.0 0.1 4.9 5 0 0 5 5 5 0 Galactose oxidase, central domain BRO1 PF03097.18 EGC37226.1 - 4.1e-32 111.5 0.0 7.6e-32 110.6 0.0 1.3 1 1 0 1 1 1 1 BRO1-like domain SeqA_N PF17206.3 EGC37227.1 - 0.061 12.7 0.1 0.18 11.1 0.1 1.7 1 0 0 1 1 1 0 SeqA protein N-terminal domain DUF1751 PF08551.10 EGC37228.1 - 7.2e-22 77.8 7.1 7.2e-22 77.8 7.1 2.2 2 1 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.22 EGC37228.1 - 1.1e-07 32.0 12.7 1.1e-07 32.0 12.7 1.6 2 0 0 2 2 2 1 Rhomboid family Pkinase_Tyr PF07714.17 EGC37230.1 - 4.2e-53 180.3 0.1 8.2e-53 179.3 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC37230.1 - 1e-51 175.9 0.7 1e-51 175.9 0.7 2.4 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC37230.1 - 4.2e-06 25.8 0.4 4.2e-06 25.8 0.4 2.6 2 1 0 2 2 2 1 Fungal protein kinase FTA2 PF13095.6 EGC37230.1 - 0.19 11.3 0.0 0.19 11.3 0.0 2.9 2 1 1 3 3 3 0 Kinetochore Sim4 complex subunit FTA2 CybS PF05328.12 EGC37231.1 - 5.9e-07 29.2 0.1 7.1e-07 29.0 0.1 1.2 1 0 0 1 1 1 1 CybS, succinate dehydrogenase cytochrome B small subunit Cullin PF00888.22 EGC37232.1 - 2.9e-146 488.6 27.3 4e-146 488.2 27.3 1.2 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.9 EGC37232.1 - 2.9e-24 84.9 0.5 9.8e-24 83.2 0.5 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain DUF3417 PF11897.8 EGC37233.1 - 0.027 14.9 0.4 0.077 13.5 0.4 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) Kelch_4 PF13418.6 EGC37235.1 - 5.6e-20 71.1 4.4 2.3e-08 33.9 0.1 5.8 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC37235.1 - 5.9e-15 54.9 4.0 7.7e-05 22.6 0.1 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_3 PF13415.6 EGC37235.1 - 2.1e-14 53.4 7.9 0.00063 20.0 0.6 6.5 7 0 0 7 7 7 2 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC37235.1 - 2.2e-09 37.3 7.7 0.089 13.1 0.1 5.5 5 1 0 5 5 5 3 Kelch motif Kelch_1 PF01344.25 EGC37235.1 - 4.1e-09 35.9 0.4 0.015 14.9 0.1 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_2 PF07646.15 EGC37235.1 - 0.00011 22.1 4.5 0.062 13.3 0.1 4.8 5 0 0 5 5 5 1 Kelch motif FNIP PF05725.12 EGC37236.1 - 2.6e-107 350.8 31.5 1.9e-15 56.7 0.2 7.5 4 2 5 9 9 9 9 FNIP Repeat LRR_5 PF13306.6 EGC37236.1 - 1.4e-07 31.5 0.0 0.0017 18.3 0.0 3.2 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC37236.1 - 0.00022 21.3 7.7 14 6.0 0.0 6.8 6 2 2 8 8 8 2 Protein of unknown function (DUF1769) CDC48_2 PF02933.17 EGC37236.1 - 0.088 12.6 0.4 42 4.0 0.0 3.9 4 0 0 4 4 4 0 Cell division protein 48 (CDC48), domain 2 CBS PF00571.28 EGC37237.1 - 3e-21 75.6 1.3 4.5e-06 27.0 0.0 4.3 4 0 0 4 4 4 3 CBS domain SMC_hinge PF06470.13 EGC37237.1 - 0.1 12.9 0.1 1.1 9.6 0.0 2.6 3 1 0 3 3 3 0 SMC proteins Flexible Hinge Domain EXS PF03124.14 EGC37239.1 - 2.8e-65 220.8 42.4 2.8e-65 220.8 42.4 1.3 1 1 0 1 1 1 1 EXS family ACT_4 PF13291.6 EGC37239.1 - 0.33 11.6 6.6 0.72 10.5 6.6 1.5 1 0 0 1 1 1 0 ACT domain LCM PF04072.14 EGC37241.1 - 4.6e-25 88.7 0.0 2.3e-24 86.4 0.0 1.9 1 1 0 1 1 1 1 Leucine carboxyl methyltransferase RNA_pol_Rpb2_6 PF00562.28 EGC37242.1 - 4.9e-130 434.1 0.3 2.4e-129 431.8 0.1 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGC37242.1 - 1.8e-68 230.1 0.2 2.7e-68 229.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.14 EGC37242.1 - 1.5e-50 171.5 0.0 3e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.20 EGC37242.1 - 4.1e-34 116.9 0.1 9.4e-34 115.7 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_3 PF04565.16 EGC37242.1 - 4.9e-25 87.5 0.1 1.1e-24 86.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_4 PF04566.13 EGC37242.1 - 1.2e-22 80.0 0.2 3.4e-22 78.5 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_5 PF04567.17 EGC37242.1 - 1.9e-20 73.2 3.0 4.6e-20 71.9 3.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 DUF4729 PF15866.5 EGC37242.1 - 0.066 12.5 0.1 5.4 6.3 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4729) MafB19-deam PF14437.6 EGC37243.1 - 1e-12 48.0 0.2 1.4e-12 47.5 0.2 1.1 1 0 0 1 1 1 1 MafB19-like deaminase dCMP_cyt_deam_1 PF00383.23 EGC37243.1 - 1.1e-12 47.7 0.5 1.5e-12 47.2 0.5 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.6 EGC37243.1 - 0.00087 19.4 0.3 0.47 10.5 0.2 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase HTH_29 PF13551.6 EGC37244.1 - 1.8e-06 27.9 0.1 2.6e-06 27.4 0.1 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.6 EGC37244.1 - 9.1e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain PAX PF00292.18 EGC37244.1 - 0.00038 20.4 0.0 0.00048 20.0 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_36 PF13730.6 EGC37244.1 - 0.00066 19.6 0.4 0.0011 18.9 0.4 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_28 PF13518.6 EGC37244.1 - 0.00088 19.4 0.0 0.0012 18.9 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EGC37244.1 - 0.0035 17.1 0.1 0.0065 16.2 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.22 EGC37244.1 - 0.0082 16.1 0.1 0.011 15.7 0.1 1.3 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.19 EGC37244.1 - 0.0096 16.1 0.1 0.013 15.7 0.1 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_32 PF13565.6 EGC37244.1 - 0.014 16.0 0.0 0.31 11.7 0.0 2.1 1 1 1 2 2 2 0 Homeodomain-like domain HTH_50 PF18024.1 EGC37244.1 - 0.021 14.4 0.3 0.028 14.0 0.3 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.19 EGC37244.1 - 0.03 14.2 0.1 0.042 13.7 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB HTH_54 PF18607.1 EGC37244.1 - 0.038 14.1 0.2 0.048 13.7 0.2 1.2 1 0 0 1 1 1 0 ParA helix turn helix domain HTH_AsnC-type PF13404.6 EGC37244.1 - 0.083 12.7 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EGC37244.1 - 0.084 12.6 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_24 PF13412.6 EGC37244.1 - 0.13 11.8 0.2 0.29 10.7 0.0 1.8 2 1 0 2 2 2 0 Winged helix-turn-helix DNA-binding Terminase_5 PF06056.12 EGC37244.1 - 0.15 12.0 0.1 0.63 10.0 0.1 1.9 1 1 1 2 2 2 0 Putative ATPase subunit of terminase (gpP-like) MCD PF05292.11 EGC37245.1 - 2e-57 194.7 0.2 1.6e-34 119.7 0.0 2.2 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase C-terminal domain Flagellar_put PF12611.8 EGC37245.1 - 4.7 7.1 8.8 1.8 8.4 0.9 3.2 3 0 0 3 3 3 0 Putative flagellar Snf7 PF03357.21 EGC37246.1 - 3.5e-28 98.4 24.9 3.5e-28 98.4 24.9 1.4 1 1 1 2 2 2 1 Snf7 Clathrin_H_link PF13838.6 EGC37246.1 - 0.14 12.1 1.8 0.23 11.4 0.2 2.1 2 0 0 2 2 2 0 Clathrin-H-link Cytochrom_B562 PF07361.11 EGC37246.1 - 0.38 11.4 17.3 0.52 11.0 1.3 2.9 1 1 1 2 2 2 0 Cytochrome b562 SHS2_FTSA PF02491.20 EGC37246.1 - 0.42 11.1 2.3 12 6.3 0.2 2.6 1 1 0 2 2 2 0 SHS2 domain inserted in FTSA LURAP PF14854.6 EGC37246.1 - 0.46 10.5 6.2 0.33 10.9 4.3 1.7 1 1 1 2 2 2 0 Leucine rich adaptor protein PXA PF02194.15 EGC37246.1 - 0.49 10.3 7.7 1.3 9.0 7.4 1.7 1 1 1 2 2 2 0 PXA domain PRT_C PF08372.10 EGC37246.1 - 0.56 10.0 3.2 0.41 10.4 1.1 1.8 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal FUSC PF04632.12 EGC37246.1 - 1.2 7.6 2.8 1.5 7.3 2.8 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family MutS_III PF05192.18 EGC37246.1 - 1.2 9.3 6.3 1.7 8.9 6.3 1.2 1 0 0 1 1 1 0 MutS domain III DUF5082 PF16888.5 EGC37246.1 - 1.9 8.8 16.5 0.9 9.8 8.1 3.2 1 1 2 3 3 3 0 Domain of unknown function (DUF5082) DUF4239 PF14023.6 EGC37246.1 - 2.1 8.0 6.9 0.7 9.6 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) DUF3837 PF12939.7 EGC37246.1 - 3.7 8.0 11.2 0.46 10.9 5.8 2.3 2 1 1 3 3 2 0 Domain of unknown function (DUF3837) Allexi_40kDa PF05549.11 EGC37246.1 - 6.3 6.2 12.0 2 7.9 3.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Snapin_Pallidin PF14712.6 EGC37246.1 - 6.4 7.3 16.4 0.88 10.0 6.7 3.1 1 1 2 3 3 3 0 Snapin/Pallidin T3SS_needle_E PF08988.10 EGC37246.1 - 9.1 6.5 8.8 6.7 6.9 0.6 3.2 1 1 1 3 3 3 0 Type III secretion system, cytoplasmic E component of needle PP2C PF00481.21 EGC37248.1 - 1.4e-33 116.6 0.0 1.8e-33 116.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGC37248.1 - 0.00015 21.5 0.0 0.00031 20.5 0.0 1.5 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.12 EGC37248.1 - 0.0064 16.4 0.0 0.025 14.5 0.0 1.9 2 1 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Copine PF07002.16 EGC37249.1 - 1.2e-59 201.5 0.1 2e-59 200.7 0.1 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC37249.1 - 2.6e-17 63.0 0.0 4.5e-09 36.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC37249.1 - 9.7e-06 25.8 0.0 1.9e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC37249.1 - 0.015 15.6 0.1 0.035 14.4 0.1 1.6 1 0 0 1 1 1 0 von Willebrand factor type A domain EMP24_GP25L PF01105.24 EGC37250.1 - 4.8e-50 170.0 1.1 6.3e-50 169.6 1.1 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cpn60_TCP1 PF00118.24 EGC37251.1 - 1.6e-86 290.9 14.4 3e-86 290.0 14.4 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RhoGAP PF00620.27 EGC37252.1 - 3.4e-34 117.9 0.0 5.2e-34 117.3 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.32 EGC37252.1 - 0.00025 21.8 10.9 0.011 16.6 0.8 5.3 5 0 0 5 5 5 1 WD domain, G-beta repeat WD40_like PF17005.5 EGC37252.1 - 0.0082 15.5 1.0 0.0082 15.5 1.0 2.0 2 0 0 2 2 2 1 WD40-like domain PQQ PF01011.21 EGC37252.1 - 0.032 14.2 0.0 0.085 12.8 0.0 1.7 1 0 0 1 1 1 0 PQQ enzyme repeat ANAPC4_WD40 PF12894.7 EGC37252.1 - 0.04 14.2 0.1 1.5 9.2 0.0 3.4 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain DUF4283 PF14111.6 EGC37252.1 - 0.062 12.8 0.1 0.18 11.3 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4283) SGL PF08450.12 EGC37252.1 - 0.089 12.4 0.1 0.25 10.9 0.1 1.8 1 1 0 1 1 1 0 SMP-30/Gluconolactonase/LRE-like region Reg_prop PF07494.11 EGC37252.1 - 0.098 12.9 4.7 13 6.4 0.0 4.7 6 0 0 6 6 6 0 Two component regulator propeller IFRD PF05004.13 EGC37253.1 - 6.9e-07 28.7 21.1 7.4e-06 25.3 21.2 2.6 1 1 1 2 2 2 1 Interferon-related developmental regulator (IFRD) DNA_pol_phi PF04931.13 EGC37253.1 - 0.00083 17.6 15.7 0.0014 16.9 15.7 1.4 1 0 0 1 1 1 1 DNA polymerase phi zf-TRAF PF02176.18 EGC37254.1 - 7.1e-18 65.1 18.3 1.1e-12 48.4 6.4 3.8 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.16 EGC37254.1 - 2.4e-05 24.4 26.5 0.0047 16.9 3.0 4.1 1 1 2 3 3 3 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC37254.1 - 0.0015 19.0 28.2 0.011 16.1 9.3 3.4 1 1 3 4 4 4 3 TRAF-like zinc-finger zf_C2HC_14 PF18574.1 EGC37254.1 - 0.0027 17.5 7.4 1.5 8.7 0.5 4.0 3 0 0 3 3 3 2 C2HC Zing finger domain zf_UBZ PF18439.1 EGC37254.1 - 0.051 13.2 0.6 0.051 13.2 0.6 4.2 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger JIP_LZII PF16471.5 EGC37254.1 - 0.068 13.4 2.5 0.095 12.9 1.1 2.0 2 0 0 2 2 2 0 JNK-interacting protein leucine zipper II PBECR1 PF18809.1 EGC37254.1 - 0.22 12.2 6.6 0.57 10.9 6.6 1.8 1 0 0 1 1 1 0 phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease1 DM PF00751.18 EGC37254.1 - 3 7.8 13.4 0.51 10.3 3.5 3.2 1 1 2 3 3 3 0 DM DNA binding domain DENN PF02141.21 EGC37255.1 - 3.3e-53 180.4 2.8 3.3e-53 180.4 2.8 3.7 4 0 0 4 4 4 1 DENN (AEX-3) domain uDENN PF03456.18 EGC37255.1 - 5.1e-11 43.1 0.4 4.2e-10 40.2 0.4 2.8 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EGC37255.1 - 1.1e-07 31.7 0.9 5e-07 29.6 0.9 2.2 1 0 0 1 1 1 1 dDENN domain Phage_Gp23 PF10669.9 EGC37255.1 - 8.4 6.7 19.5 0.039 14.3 7.3 2.8 2 1 0 2 2 2 0 Protein gp23 (Bacteriophage A118) FNIP PF05725.12 EGC37256.1 - 6.5e-31 106.2 36.3 3.5e-09 36.7 0.3 8.3 4 1 5 9 9 9 8 FNIP Repeat zf-B_box PF00643.24 EGC37256.1 - 7.7e-08 32.4 4.5 1.8e-07 31.2 4.5 1.7 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC37256.1 - 0.00095 19.3 4.4 0.002 18.2 4.4 1.5 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-C2HC5 PF06221.13 EGC37256.1 - 0.22 11.5 3.3 0.45 10.5 2.4 2.0 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Rho_Binding PF08912.11 EGC37256.1 - 0.58 11.0 4.2 0.31 11.9 0.9 2.2 2 0 0 2 2 2 0 Rho Binding Big_9 PF17963.1 EGC37257.1 - 1e-08 35.8 85.1 6e-05 23.7 1.3 12.0 12 0 0 12 12 12 7 Bacterial Ig domain VWA PF00092.28 EGC37257.1 - 8.8e-06 26.1 0.1 8.8e-06 26.1 0.1 2.5 3 0 0 3 3 3 1 von Willebrand factor type A domain Cadherin_3 PF16184.5 EGC37257.1 - 0.0045 17.0 12.6 5.6 7.0 0.6 7.1 7 0 0 7 7 7 1 Cadherin-like CymA PF16941.5 EGC37257.1 - 0.027 13.7 0.1 0.5 9.5 0.0 2.2 2 0 0 2 2 2 0 Putative cyclodextrin porin Cadherin_4 PF17803.1 EGC37257.1 - 0.068 13.8 0.3 0.068 13.8 0.3 11.3 11 1 0 11 11 11 0 Bacterial cadherin-like domain Cadherin_5 PF17892.1 EGC37257.1 - 1.8 8.6 17.4 0.24 11.4 0.4 5.8 6 1 1 7 7 7 0 Cadherin-like domain Myotub-related PF06602.14 EGC37258.1 - 9.9e-48 162.8 3.6 9.9e-48 162.8 3.6 3.1 4 1 0 4 4 4 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.17 EGC37258.1 - 8.7e-47 159.6 0.0 1.8e-46 158.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC37258.1 - 8e-39 133.6 0.0 3.4e-38 131.5 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain LRR_8 PF13855.6 EGC37258.1 - 1.3e-28 98.5 76.7 1.2e-08 34.6 4.6 9.6 5 2 4 10 10 10 8 Leucine rich repeat LRR_4 PF12799.7 EGC37258.1 - 8.8e-22 76.8 94.0 4e-07 30.3 1.3 13.3 8 1 3 12 12 12 9 Leucine Rich repeats (2 copies) COR PF16095.5 EGC37258.1 - 2.2e-13 50.5 8.2 3.5e-05 23.7 0.1 4.5 4 0 0 4 4 4 3 C-terminal of Roc, COR, domain RhoGAP PF00620.27 EGC37258.1 - 1.3e-10 41.3 0.1 1.3e-10 41.3 0.1 3.4 2 1 0 2 2 2 1 RhoGAP domain APH PF01636.23 EGC37258.1 - 0.0098 15.8 0.0 0.017 15.0 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Roc PF08477.13 EGC37258.1 - 0.01 16.0 0.9 0.045 14.0 0.9 2.2 1 0 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase PAP_central PF04928.17 EGC37259.1 - 5.7e-92 307.2 0.0 1e-91 306.3 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.15 EGC37259.1 - 6.8e-32 110.4 0.2 7.6e-20 71.2 0.1 2.7 1 1 1 2 2 2 2 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.23 EGC37259.1 - 2.3e-10 40.6 0.0 5.1e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain Polbeta PF18765.1 EGC37259.1 - 0.02 14.9 0.0 0.051 13.7 0.0 1.6 1 0 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase DUF908 PF06012.12 EGC37259.1 - 0.13 11.6 10.7 0.27 10.6 10.7 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) TENA_THI-4 PF03070.16 EGC37260.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.3 1 0 0 1 1 1 0 TENA/THI-4/PQQC family Imm59 PF15597.6 EGC37263.1 - 0.32 11.5 0.1 0.32 11.5 0.1 4.3 4 0 0 4 4 4 0 Immunity protein 59 EF-hand_1 PF00036.32 EGC37264.1 - 5.8e-11 41.1 11.7 2.8e-06 26.5 0.5 4.5 4 1 1 5 5 5 2 EF hand EF-hand_6 PF13405.6 EGC37264.1 - 3.8e-10 38.8 10.5 0.00019 21.1 0.0 4.4 5 1 1 6 6 6 2 EF-hand domain EF-hand_7 PF13499.6 EGC37264.1 - 9.6e-09 35.6 7.1 0.0027 18.1 4.9 3.0 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC37264.1 - 2e-08 33.3 5.6 0.00083 18.7 0.2 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.6 EGC37264.1 - 4e-08 33.0 11.8 0.0024 17.7 2.9 3.7 1 1 2 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC37264.1 - 0.058 13.7 0.4 0.44 10.9 0.2 2.4 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGC37264.1 - 0.076 13.0 2.5 0.33 10.9 0.1 2.8 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand PriCT_1 PF08708.11 EGC37264.1 - 0.12 12.1 0.0 12 5.7 0.0 2.3 1 1 1 2 2 2 0 Primase C terminal 1 (PriCT-1) S_100 PF01023.19 EGC37264.1 - 0.15 11.8 7.1 1.2 8.9 0.5 3.8 3 1 1 4 4 4 0 S-100/ICaBP type calcium binding domain ASFV_J13L PF05568.11 EGC37265.1 - 0.059 13.1 0.3 0.13 12.0 0.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein Insulin_TMD PF17870.1 EGC37265.1 - 0.079 13.0 1.8 0.21 11.7 1.8 1.7 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment G8 PF10162.9 EGC37265.1 - 1.2 9.3 9.3 15 5.7 0.1 4.7 3 2 0 5 5 5 0 G8 domain G8 PF10162.9 EGC37266.1 - 0.0013 18.8 0.9 9.7 6.3 0.1 4.9 2 2 1 3 3 3 2 G8 domain Myc_target_1 PF15179.6 EGC37266.1 - 0.0045 16.9 0.7 0.013 15.5 0.7 1.7 1 0 0 1 1 1 1 Myc target protein 1 TFIIIC_sub6 PF10419.9 EGC37267.1 - 0.0036 17.1 0.2 0.059 13.2 0.0 2.4 2 0 0 2 2 2 1 TFIIIC subunit triple barrel domain DUF4083 PF13314.6 EGC37267.1 - 0.11 12.5 0.1 0.11 12.5 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Adeno_E3_CR2 PF02439.15 EGC37268.1 - 0.0037 17.0 1.6 0.0089 15.8 1.6 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 G8 PF10162.9 EGC37268.1 - 0.031 14.3 4.4 18 5.4 0.1 4.1 3 3 0 3 3 3 0 G8 domain EphA2_TM PF14575.6 EGC37268.1 - 0.045 14.6 0.1 0.093 13.6 0.1 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain TMIE PF16038.5 EGC37268.1 - 0.17 11.8 0.0 0.35 10.7 0.0 1.4 1 0 0 1 1 1 0 TMIE protein Syndecan PF01034.20 EGC37268.1 - 0.22 11.4 0.1 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 Syndecan domain TMEM51 PF15345.6 EGC37269.1 - 0.0012 18.8 0.6 0.0023 17.8 0.6 1.5 1 0 0 1 1 1 1 Transmembrane protein 51 ETRAMP PF09716.10 EGC37269.1 - 0.0012 18.9 0.8 0.22 11.6 3.6 2.5 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 EGC37269.1 - 0.0015 18.8 0.3 0.0045 17.3 0.3 1.8 1 0 0 1 1 1 1 Orf78 (ac78) Amnionless PF14828.6 EGC37269.1 - 0.0042 16.0 0.1 2.4 6.9 0.1 2.7 3 0 0 3 3 3 2 Amnionless DUF2407_C PF13373.6 EGC37269.1 - 0.057 13.6 0.6 0.11 12.7 0.6 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain TMEM154 PF15102.6 EGC37269.1 - 0.13 12.2 0.0 0.13 12.2 0.0 3.0 3 0 0 3 3 3 0 TMEM154 protein family G8 PF10162.9 EGC37269.1 - 0.2 11.7 5.0 1.7 8.7 0.2 3.7 1 1 2 3 3 3 0 G8 domain NOA36 PF06524.12 EGC37269.1 - 1.8 7.8 6.6 2.8 7.2 6.6 1.2 1 0 0 1 1 1 0 NOA36 protein IP_trans PF02121.18 EGC37270.1 - 8.3e-112 372.7 2.3 9.4e-112 372.5 2.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Ribosomal_L22e PF01776.17 EGC37271.1 - 2.7e-43 146.8 3.9 3.2e-43 146.6 3.9 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Mur_ligase PF01225.25 EGC37271.1 - 0.039 14.3 0.0 0.05 13.9 0.0 1.2 1 0 0 1 1 1 0 Mur ligase family, catalytic domain DUF5600 PF18150.1 EGC37272.1 - 1.6e-39 134.8 2.3 1.6e-39 134.8 2.3 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF5600) EF-hand_4 PF12763.7 EGC37272.1 - 2.4e-19 69.2 0.1 9.5e-19 67.3 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand EHD_N PF16880.5 EGC37272.1 - 3.2e-14 52.5 0.2 5.8e-14 51.7 0.2 1.4 1 0 0 1 1 1 1 N-terminal EH-domain containing protein Dynamin_N PF00350.23 EGC37272.1 - 4.8e-14 52.8 0.0 1.3e-12 48.1 0.0 2.4 1 1 0 1 1 1 1 Dynamin family MMR_HSR1 PF01926.23 EGC37272.1 - 1.3e-08 34.9 0.0 2.8e-08 33.8 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Roc PF08477.13 EGC37272.1 - 0.00012 22.3 0.0 0.42 10.9 0.0 2.4 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase GTP_EFTU PF00009.27 EGC37272.1 - 0.0067 16.0 0.0 0.023 14.2 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.18 EGC37272.1 - 0.016 14.8 0.0 2.2 7.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B SAS-6_N PF16531.5 EGC37272.1 - 0.029 15.0 0.0 0.14 12.8 0.0 2.1 1 1 1 2 2 2 0 Centriolar protein SAS N-terminal AAA_28 PF13521.6 EGC37272.1 - 0.071 13.4 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain Gtr1_RagA PF04670.12 EGC37272.1 - 0.073 12.4 0.1 0.38 10.1 0.1 2.0 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGC37272.1 - 0.1 12.4 0.0 2.2 8.0 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation TsaE PF02367.17 EGC37272.1 - 0.16 12.0 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE 14-3-3 PF00244.20 EGC37273.1 - 0.05 13.1 0.0 0.058 12.9 0.0 1.0 1 0 0 1 1 1 0 14-3-3 protein DUF599 PF04654.12 EGC37274.1 - 3.2e-58 196.6 11.4 3.9e-58 196.3 11.4 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 CPP1-like PF11833.8 EGC37274.1 - 6.6 6.3 10.5 0.25 11.0 4.4 1.7 2 0 0 2 2 2 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Cpn60_TCP1 PF00118.24 EGC37275.1 - 3e-85 286.7 4.9 1.7e-74 251.2 1.9 3.0 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family APP_N PF02177.16 EGC37275.1 - 0.029 14.7 0.6 0.13 12.6 0.6 2.2 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding NMO PF03060.15 EGC37276.1 - 5.2e-60 203.6 0.0 7.2e-60 203.1 0.0 1.1 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGC37276.1 - 9.7e-07 28.1 0.0 0.0002 20.5 0.0 2.4 2 1 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.21 EGC37276.1 - 6.7e-05 22.5 0.1 0.00052 19.5 0.0 2.0 2 0 0 2 2 2 1 Histidine biosynthesis protein G3P_antiterm PF04309.12 EGC37276.1 - 0.0024 17.3 0.0 0.008 15.6 0.0 1.8 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator DUF561 PF04481.12 EGC37276.1 - 0.076 12.2 0.2 0.15 11.2 0.2 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF561) IGPS PF00218.21 EGC37276.1 - 0.096 11.8 0.0 9.4 5.3 0.0 2.4 2 0 0 2 2 2 0 Indole-3-glycerol phosphate synthase Pkinase PF00069.25 EGC37277.1 - 5e-30 104.7 3.2 5.5e-30 104.6 3.2 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37277.1 - 6.3e-23 81.4 0.5 6.6e-23 81.3 0.5 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase NCD1 PF04904.13 EGC37277.1 - 0.0049 16.8 0.0 0.0097 15.9 0.0 1.6 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) DHHC PF01529.20 EGC37278.1 - 2.5e-30 105.3 6.6 2.5e-30 105.3 6.6 3.1 2 1 1 3 3 2 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGC37278.1 - 1.1e-29 102.8 0.0 3.2e-09 37.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC37278.1 - 4.7e-29 100.1 0.4 3.8e-08 33.4 0.0 5.1 2 1 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC37278.1 - 4.9e-28 94.1 0.5 1.2e-06 28.4 0.0 6.4 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.6 EGC37278.1 - 3.8e-26 91.1 3.8 1.3e-11 44.8 0.0 5.3 4 1 3 7 7 7 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC37278.1 - 3e-22 78.0 0.0 2.2e-07 31.0 0.0 5.5 4 1 0 4 4 4 4 Ankyrin repeat DUF4834 PF16118.5 EGC37278.1 - 0.27 12.2 0.0 0.27 12.2 0.0 2.6 3 0 0 3 3 2 0 Domain of unknown function (DUF4834) PBP1_TM PF14812.6 EGC37278.1 - 0.91 9.9 7.0 1.8 9.0 7.0 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FAM176 PF14851.6 EGC37278.1 - 1.8 8.2 7.3 3.4 7.3 7.3 1.3 1 0 0 1 1 1 0 FAM176 family UPF0560 PF10577.9 EGC37278.1 - 4.1 5.8 6.2 5.8 5.3 6.2 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DNA_pol_phi PF04931.13 EGC37278.1 - 7 4.6 9.1 10 4.1 9.1 1.1 1 0 0 1 1 1 0 DNA polymerase phi DUF900 PF05990.12 EGC37281.1 - 1.8e-24 86.6 0.1 2.6e-24 86.1 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_6 PF12697.7 EGC37281.1 - 0.007 17.0 0.0 0.011 16.3 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2968 PF11180.8 EGC37282.1 - 0.075 12.7 2.9 0.09 12.4 2.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) ERM PF00769.19 EGC37282.1 - 0.22 11.3 13.8 0.25 11.1 13.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family TMPIT PF07851.13 EGC37282.1 - 0.28 10.4 11.5 0.32 10.2 11.5 1.0 1 0 0 1 1 1 0 TMPIT-like protein zf-RING_2 PF13639.6 EGC37283.1 - 1.5e-09 38.0 9.9 3.1e-09 37.0 9.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37283.1 - 2.3e-07 30.6 10.9 2.8e-07 30.3 8.1 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37283.1 - 2.6e-07 30.4 7.2 4.1e-07 29.7 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37283.1 - 3.6e-07 30.4 5.3 8.5e-06 26.0 5.5 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC37283.1 - 4.1e-07 29.7 10.6 8.8e-07 28.7 10.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37283.1 - 0.00058 19.8 8.6 0.0011 18.9 8.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC37283.1 - 0.0012 18.9 4.3 0.0012 18.9 4.3 1.9 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC37283.1 - 0.0091 15.8 7.6 0.016 15.0 7.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGC37283.1 - 0.016 15.0 6.7 0.031 14.1 6.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Baculo_IE-1 PF05290.11 EGC37283.1 - 0.032 14.2 2.4 0.059 13.3 2.4 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-ANAPC11 PF12861.7 EGC37283.1 - 0.04 14.0 1.1 0.17 11.9 1.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC37283.1 - 0.063 13.0 6.9 0.15 11.8 6.9 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EGC37283.1 - 0.092 12.9 3.8 0.22 11.7 3.8 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC37283.1 - 0.2 11.8 12.2 0.13 12.5 9.9 1.9 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.11 EGC37283.1 - 0.27 11.3 6.6 0.57 10.3 6.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 EGC37283.1 - 0.29 11.0 2.7 0.69 9.8 2.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DZR PF12773.7 EGC37283.1 - 0.67 10.0 5.7 1.3 9.1 5.7 1.5 1 0 0 1 1 1 0 Double zinc ribbon IBR PF01485.21 EGC37283.1 - 3.7 7.9 8.5 24 5.2 8.5 2.4 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain zf-RING_2 PF13639.6 EGC37284.1 - 7.3e-10 39.0 9.6 1.2e-09 38.4 9.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37284.1 - 1.6e-08 34.3 8.0 2.7e-08 33.5 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37284.1 - 1.8e-08 34.1 7.4 2.8e-08 33.5 7.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37284.1 - 5.5e-07 29.3 10.4 9.9e-07 28.5 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37284.1 - 2.9e-06 27.5 5.2 7.8e-06 26.1 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC37284.1 - 2.3e-05 24.3 4.1 4.6e-05 23.3 4.1 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC37284.1 - 7.1e-05 22.7 9.3 0.00012 21.9 9.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC37284.1 - 0.0012 18.7 5.8 0.0022 17.8 5.8 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC37284.1 - 0.0013 18.4 9.5 0.0023 17.7 9.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGC37284.1 - 0.0025 17.5 6.6 0.0044 16.7 6.6 1.4 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC37284.1 - 0.0035 17.3 1.1 0.0087 16.1 1.1 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC37284.1 - 0.11 12.6 10.4 0.29 11.3 10.4 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RVT PF13966.6 EGC37284.1 - 0.18 12.5 1.7 0.46 11.2 1.7 1.7 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase DZR PF12773.7 EGC37284.1 - 0.28 11.3 4.5 0.64 10.1 4.5 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf_Rg PF17915.1 EGC37284.1 - 0.46 9.9 3.3 26 4.3 0.1 3.3 3 0 0 3 3 3 0 Reverse gyrase zinc finger DUF1272 PF06906.11 EGC37284.1 - 0.46 10.6 6.0 1.1 9.5 6.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_6 PF14835.6 EGC37284.1 - 0.47 10.4 3.3 1 9.3 3.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Otopetrin PF03189.13 EGC37284.1 - 6.5 5.5 5.7 11 4.8 5.7 1.3 1 0 0 1 1 1 0 Otopetrin Ras PF00071.22 EGC37288.1 - 2.7e-20 72.6 0.5 1.1e-17 64.2 0.2 2.7 2 1 0 2 2 2 2 Ras family Roc PF08477.13 EGC37288.1 - 2.2e-14 53.7 0.8 4.2e-13 49.6 0.1 3.2 3 0 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC37288.1 - 1.6e-08 34.2 2.3 4.2e-07 29.6 0.6 2.5 2 0 0 2 2 2 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC37288.1 - 1e-06 28.8 0.2 4.5e-06 26.7 0.2 2.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC37288.1 - 3.3e-05 24.0 0.1 3.3e-05 24.0 0.1 2.6 2 2 0 2 2 2 1 Dynamin family 4HBT PF03061.22 EGC37289.1 - 6e-09 36.1 0.0 0.00039 20.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.22 EGC37289.1 - 2.4e-06 27.3 0.1 7.5e-06 25.7 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3275 PF11679.8 EGC37290.1 - 0.75 9.7 5.0 1.1 9.1 5.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) PHD_3 PF13922.6 EGC37290.1 - 0.97 9.9 5.2 2.4 8.6 5.2 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx RIFIN PF02009.16 EGC37290.1 - 4.1 7.2 12.6 8.6 6.1 12.5 1.6 1 1 0 1 1 1 0 Rifin TIG PF01833.24 EGC37291.1 - 2.9e-12 46.5 41.1 0.00025 21.1 1.6 7.1 7 0 0 7 7 7 6 IPT/TIG domain HPD PF05044.12 EGC37291.1 - 0.025 14.4 0.0 2 8.3 0.0 2.6 2 0 0 2 2 2 0 Homeo-prospero domain EGF_2 PF07974.13 EGC37291.1 - 0.05 14.0 11.5 0.12 12.8 11.5 1.6 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 EGC37291.1 - 4.9 7.4 8.6 14 5.9 8.6 1.7 1 0 0 1 1 1 0 Laminin EGF domain Glycos_transf_2 PF00535.26 EGC37292.1 - 2e-38 131.9 0.0 2.5e-38 131.6 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.6 EGC37292.1 - 1.3e-14 54.6 0.0 1.9e-14 54.1 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.6 EGC37292.1 - 4.8e-05 22.9 0.0 6.9e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_2 PF10111.9 EGC37292.1 - 0.00045 19.8 0.0 0.00063 19.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_4 PF13704.6 EGC37292.1 - 0.0063 17.0 0.0 0.016 15.7 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_transf_7N PF13733.6 EGC37292.1 - 0.0098 15.5 0.0 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal region of glycosyl transferase group 7 Glyco_hydro_20 PF00728.22 EGC37294.1 - 5.9e-87 292.3 1.3 7.6e-87 292.0 1.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGC37294.1 - 1.4e-13 51.6 0.5 4.3e-13 50.1 0.5 1.8 1 1 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGC37294.1 - 1.1e-07 32.7 0.0 1.9e-07 31.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 LTV PF04180.14 EGC37296.1 - 0.00022 21.1 19.5 0.00022 21.1 19.5 4.6 1 1 3 4 4 4 3 Low temperature viability protein IMUP PF15761.5 EGC37296.1 - 0.011 16.4 4.1 0.023 15.4 4.1 1.5 1 0 0 1 1 1 0 Immortalisation up-regulated protein FAM199X PF15814.5 EGC37296.1 - 2.4 7.1 9.7 4.1 6.4 9.7 1.2 1 0 0 1 1 1 0 Protein family FAM199X WWE PF02825.20 EGC37297.1 - 1.5e-05 25.5 4.9 0.025 15.2 1.3 2.9 2 0 0 2 2 2 2 WWE domain WWE PF02825.20 EGC37298.1 - 1.7e-09 38.1 11.7 3.2e-08 34.0 3.5 2.9 3 0 0 3 3 3 2 WWE domain Spot_14 PF07084.12 EGC37298.1 - 0.035 14.3 0.4 0.35 11.0 0.1 2.2 1 1 1 2 2 2 0 Thyroid hormone-inducible hepatic protein Spot 14 IBR PF01485.21 EGC37299.1 - 2.1e-13 50.3 25.6 7.8e-12 45.2 4.8 3.8 4 1 0 4 4 4 2 IBR domain, a half RING-finger domain UBA_4 PF14555.6 EGC37299.1 - 0.00036 20.3 0.1 0.82 9.5 0.0 2.8 3 0 0 3 3 3 2 UBA-like domain zf-C3HC4_3 PF13920.6 EGC37299.1 - 0.001 18.9 6.8 0.001 18.9 6.8 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37299.1 - 0.0042 16.9 3.0 0.0042 16.9 3.0 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37299.1 - 0.018 14.9 3.6 0.018 14.9 3.6 4.4 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) WSD PF15613.6 EGC37299.1 - 0.064 13.7 0.1 0.32 11.5 0.0 2.2 2 0 0 2 2 2 0 Williams-Beuren syndrome DDT (WSD), D-TOX E motif Cyt-b5 PF00173.28 EGC37300.1 - 2.5e-15 56.4 0.1 4.7e-15 55.5 0.1 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Skp1_POZ PF03931.15 EGC37300.1 - 0.033 14.4 1.5 0.12 12.5 1.5 2.0 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain EKAL PF17986.1 EGC37300.1 - 0.17 11.9 3.7 0.14 12.2 1.0 2.2 2 0 0 2 2 2 0 EMP3-KAHRP-like N-terminal domain UQ_con PF00179.26 EGC37301.1 - 4.6e-20 71.7 0.2 9.4e-20 70.7 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mucin PF01456.17 EGC37301.1 - 2.5e-05 24.3 12.4 3.1e-05 24.0 12.4 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein 7TM_GPCR_Srd PF10317.9 EGC37301.1 - 0.019 14.2 2.4 0.029 13.6 2.4 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Pex14_N PF04695.13 EGC37301.1 - 0.03 15.0 2.3 0.052 14.2 2.3 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MGC-24 PF05283.11 EGC37301.1 - 0.032 14.7 11.0 0.055 13.9 11.0 1.4 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin Zip PF02535.22 EGC37301.1 - 0.12 11.5 0.8 0.17 11.0 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DAG_kinase_N PF14513.6 EGC37301.1 - 0.13 12.4 2.2 0.2 11.9 2.2 1.4 1 0 0 1 1 1 0 Diacylglycerol kinase N-terminus RWD PF05773.22 EGC37301.1 - 0.19 12.0 0.0 0.19 12.0 0.0 2.1 2 1 0 2 2 2 0 RWD domain Menin PF05053.13 EGC37301.1 - 0.31 9.4 6.3 0.39 9.0 6.3 1.1 1 0 0 1 1 1 0 Menin MAP70 PF07058.11 EGC37301.1 - 0.74 8.5 6.2 1 8.1 6.2 1.2 1 0 0 1 1 1 0 Microtubule-associated protein 70 HCO3_cotransp PF00955.21 EGC37301.1 - 0.98 8.2 5.9 1.2 7.8 5.9 1.1 1 0 0 1 1 1 0 HCO3- transporter family FSA_C PF10479.9 EGC37301.1 - 1.2 7.1 14.6 1.6 6.8 14.6 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus TMEM154 PF15102.6 EGC37301.1 - 2.1 8.2 18.8 8.9 6.2 18.8 1.9 1 1 0 1 1 1 0 TMEM154 protein family zf-B_box PF00643.24 EGC37302.1 - 3.7e-07 30.2 10.3 8.2e-07 29.1 10.3 1.6 1 0 0 1 1 1 1 B-box zinc finger Kelch_4 PF13418.6 EGC37302.1 - 1.4e-06 28.2 11.5 0.07 13.1 0.1 5.0 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC37302.1 - 0.0002 21.5 11.6 0.85 10.0 0.2 5.6 4 1 2 6 6 6 2 Kelch motif Kelch_5 PF13854.6 EGC37302.1 - 0.0061 16.5 6.2 2.1 8.4 0.2 4.3 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.6 EGC37302.1 - 0.009 16.3 14.0 0.092 13.1 0.0 5.1 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC37302.1 - 8.4 6.1 10.4 6.9 6.3 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Histone PF00125.24 EGC37303.1 - 1.5e-19 70.7 0.3 1.8e-19 70.4 0.3 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.23 EGC37303.1 - 1.2e-06 28.7 0.2 1.7e-06 28.2 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.13 EGC37303.1 - 0.0011 19.4 0.0 0.0022 18.5 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF4364 PF14277.6 EGC37303.1 - 0.0065 16.2 0.2 0.007 16.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4364) CENP-T_C PF15511.6 EGC37303.1 - 0.007 16.5 0.2 0.0079 16.3 0.2 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC37303.1 - 0.059 13.8 0.1 0.083 13.3 0.1 1.2 1 0 0 1 1 1 0 CENP-S protein Gram_pos_anchor PF00746.21 EGC37303.1 - 3.6 7.6 0.0 3.6 7.6 0.0 2.5 3 0 0 3 3 3 0 LPXTG cell wall anchor motif Methyltrn_RNA_3 PF02598.17 EGC37304.1 - 2.6e-63 214.2 1.0 4.3e-63 213.5 1.0 1.3 1 0 0 1 1 1 1 Putative RNA methyltransferase DUF496 PF04363.12 EGC37304.1 - 0.57 10.2 17.6 0.14 12.2 3.7 4.0 3 1 1 4 4 4 0 Protein of unknown function (DUF496) HTH_57 PF18679.1 EGC37304.1 - 0.86 9.9 3.8 0.95 9.8 0.1 2.8 1 1 2 3 3 3 0 ThcOx helix turn helix domain PIG-H PF10181.9 EGC37305.1 - 2.4e-18 65.8 0.6 5.8e-18 64.5 0.6 1.7 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component eIF-5_eIF-2B PF01873.17 EGC37307.1 - 6.2e-36 122.8 1.0 1.2e-35 121.9 0.2 1.9 2 0 0 2 2 2 1 Domain found in IF2B/IF5 W2 PF02020.18 EGC37307.1 - 3e-20 72.1 0.8 3e-20 72.1 0.8 2.0 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Zn_Tnp_IS1595 PF12760.7 EGC37307.1 - 0.18 11.8 0.6 0.35 10.9 0.6 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain DUF4769 PF15992.5 EGC37307.1 - 0.58 9.9 2.7 0.98 9.2 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4769) Abhydrolase_3 PF07859.13 EGC37308.1 - 3.6e-44 151.2 0.0 4.5e-44 150.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGC37308.1 - 9.8e-14 51.0 0.1 1.6e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGC37308.1 - 2.2e-05 24.1 0.0 0.0097 15.4 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family DLH PF01738.18 EGC37308.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S10 PF00450.22 EGC37308.1 - 0.088 12.2 0.1 0.16 11.3 0.0 1.5 2 0 0 2 2 2 0 Serine carboxypeptidase Abhydrolase_3 PF07859.13 EGC37309.1 - 1.9e-57 194.5 0.0 2.5e-57 194.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGC37309.1 - 1.5e-08 34.0 0.1 2.2e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase Peptidase_S9 PF00326.21 EGC37309.1 - 0.00014 21.4 0.0 0.00045 19.8 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family COesterase PF00135.28 EGC37309.1 - 0.0052 15.7 0.0 0.1 11.4 0.0 2.0 2 0 0 2 2 2 1 Carboxylesterase family Chlorophyllase2 PF12740.7 EGC37309.1 - 0.022 13.7 0.1 0.082 11.8 0.1 1.9 1 1 0 1 1 1 0 Chlorophyllase enzyme Abhydrolase_3 PF07859.13 EGC37310.1 - 1.4e-63 214.6 0.0 1.7e-63 214.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGC37310.1 - 2.2e-08 33.4 0.1 3.2e-08 32.8 0.1 1.1 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGC37310.1 - 8.4e-06 24.9 0.0 0.022 13.6 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.21 EGC37310.1 - 3.6e-05 23.4 0.1 0.00028 20.4 0.1 2.0 1 1 0 1 1 1 1 Prolyl oligopeptidase family Esterase_phd PF10503.9 EGC37310.1 - 0.0013 18.2 0.1 0.011 15.3 0.0 2.4 2 1 0 2 2 2 1 Esterase PHB depolymerase Lipase_3 PF01764.25 EGC37310.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) DUF2974 PF11187.8 EGC37310.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_3 PF07859.13 EGC37311.1 - 1.7e-64 217.5 0.0 2.2e-64 217.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC37311.1 - 4.1e-06 26.4 0.1 1.1e-05 25.0 0.1 1.6 1 1 0 1 1 1 1 Prolyl oligopeptidase family Say1_Mug180 PF10340.9 EGC37311.1 - 6.1e-06 25.3 0.0 7.9e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGC37311.1 - 1.1e-05 24.6 0.0 0.014 14.3 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Esterase_phd PF10503.9 EGC37311.1 - 0.0032 17.0 0.1 0.13 11.8 0.0 2.7 2 1 0 2 2 2 1 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGC37311.1 - 0.01 15.1 0.0 0.16 11.2 0.0 2.3 1 1 1 2 2 2 0 Serine aminopeptidase, S33 DUF2974 PF11187.8 EGC37311.1 - 0.048 13.2 0.0 0.074 12.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) tRNA-synt_2 PF00152.20 EGC37312.1 - 1.1e-77 261.2 0.0 1.7e-77 260.6 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.25 EGC37312.1 - 3e-07 30.3 0.1 1.5e-05 24.9 0.2 2.9 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGC37312.1 - 3.8e-07 29.9 0.0 0.0029 17.1 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) TetR_C_8 PF14278.6 EGC37313.1 - 0.32 11.1 4.8 0.85 9.8 0.1 3.7 3 0 0 3 3 3 0 Transcriptional regulator C-terminal region Shugoshin_N PF07558.11 EGC37313.1 - 0.97 9.4 8.8 7.8 6.5 0.1 3.2 3 0 0 3 3 3 0 Shugoshin N-terminal coiled-coil region Sigma_reg_N PF13800.6 EGC37314.1 - 0.065 13.5 0.5 0.12 12.6 0.5 1.5 1 0 0 1 1 1 0 Sigma factor regulator N-terminal DUF4834 PF16118.5 EGC37314.1 - 0.84 10.6 4.3 4.7 8.2 4.3 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) FAM163 PF15069.6 EGC37314.1 - 3.4 8.1 6.5 9.6 6.6 6.5 1.9 1 1 0 1 1 1 0 FAM163 family ECSCR PF15820.5 EGC37314.1 - 5.4 6.9 4.8 18 5.2 4.8 1.7 1 1 0 1 1 1 0 Endothelial cell-specific chemotaxis regulator RhoGEF PF00621.20 EGC37315.1 - 3.8e-32 112.0 11.9 3.8e-32 112.0 11.9 2.5 3 0 0 3 3 3 1 RhoGEF domain Pterin_bind PF00809.22 EGC37315.1 - 0.0017 18.1 0.1 0.0033 17.2 0.1 1.4 1 0 0 1 1 1 1 Pterin binding enzyme RPOL_N PF14700.6 EGC37315.1 - 5.9 6.2 7.1 0.37 10.1 0.3 2.3 3 0 0 3 3 3 0 DNA-directed RNA polymerase N-terminal Ribosomal_L14 PF00238.19 EGC37316.1 - 2.5e-31 108.3 0.1 3e-31 108.1 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cyt-b5 PF00173.28 EGC37317.1 - 3.8e-18 65.4 0.0 6.2e-18 64.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.10 EGC37317.1 - 5.5e-07 29.7 0.4 1.7e-06 28.1 0.4 1.9 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type SNF2_N PF00176.23 EGC37318.1 - 5.5e-62 209.5 0.5 1.1e-61 208.5 0.5 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC37318.1 - 1.4e-18 67.3 0.0 7.1e-18 65.0 0.0 2.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGC37318.1 - 9.4e-14 51.1 23.5 1.8e-08 34.2 2.6 4.9 5 0 0 5 5 5 2 Chromo (CHRromatin Organisation MOdifier) domain CHDCT2 PF08074.11 EGC37318.1 - 0.00016 21.9 0.0 0.00016 21.9 0.0 5.5 6 1 0 6 6 6 2 CHDCT2 (NUC038) domain DEAD PF00270.29 EGC37318.1 - 0.0077 16.0 0.0 0.019 14.7 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF1086 PF06461.11 EGC37318.1 - 1 9.3 9.6 1.9 8.3 0.0 3.4 3 0 0 3 3 3 0 Domain of Unknown Function (DUF1086) GCV_H PF01597.19 EGC37320.1 - 1.8e-12 47.2 0.6 2.1e-12 47.0 0.6 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.6 EGC37320.1 - 0.18 11.7 0.4 0.33 10.8 0.2 1.5 2 0 0 2 2 2 0 Biotin-lipoyl like Vel1p PF10339.9 EGC37321.1 - 0.042 13.2 0.0 0.049 13.0 0.0 1.0 1 0 0 1 1 1 0 Yeast-specific zinc responsive OEP PF02321.18 EGC37322.1 - 0.19 11.5 6.0 0.45 10.3 6.0 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DEC-1_N PF04625.13 EGC37322.1 - 1.1 8.2 11.0 0.33 9.9 8.0 1.5 1 1 0 1 1 1 0 DEC-1 protein, N-terminal region TMPIT PF07851.13 EGC37322.1 - 4.2 6.5 22.3 0.63 9.2 13.0 2.0 2 0 0 2 2 2 0 TMPIT-like protein XPG_I PF00867.18 EGC37322.1 - 8 6.9 6.5 2.7 8.4 0.3 2.8 1 1 1 2 2 2 0 XPG I-region Transferase PF02458.15 EGC37323.1 - 3.6e-11 42.4 0.0 5e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.20 EGC37323.1 - 0.0002 20.2 0.0 0.00036 19.3 0.0 1.3 1 0 0 1 1 1 1 Condensation domain DUF3920 PF13058.6 EGC37323.1 - 0.019 15.2 3.4 0.02 15.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3920) tRNA-synt_1d PF00750.19 EGC37324.1 - 3.9e-76 256.3 0.0 2.3e-74 250.5 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class I (R) DALR_1 PF05746.15 EGC37324.1 - 3.9e-24 85.1 0.0 6.9e-23 81.1 0.0 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.16 EGC37324.1 - 0.012 16.2 1.0 0.059 14.0 0.8 2.3 2 0 0 2 2 2 0 Arginyl tRNA synthetase N terminal domain Ntox21 PF15526.6 EGC37324.1 - 1.4 9.2 4.8 0.49 10.7 0.1 2.7 3 0 0 3 3 3 0 Novel toxin 21 FragX_IP PF05994.11 EGC37325.1 - 1.3e-300 999.4 11.2 1.3e-300 999.4 11.2 1.7 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.12 EGC37325.1 - 9.6e-16 57.9 7.1 5.3e-15 55.5 7.1 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) Apis_Csd PF11671.8 EGC37326.1 - 4.5 7.3 15.0 4.8 7.2 15.0 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein GMC_oxred_N PF00732.19 EGC37327.1 - 5.6e-39 134.3 0.0 7.5e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.13 EGC37327.1 - 2.9e-24 86.2 0.0 4.4e-24 85.6 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase PglD_N PF17836.1 EGC37328.1 - 0.21 12.3 2.3 1.5 9.5 0.6 2.6 2 0 0 2 2 2 0 PglD N-terminal domain Nucleoporin_C PF03177.14 EGC37329.1 - 1.5e-16 60.3 9.6 1.5e-16 60.3 9.6 2.9 2 2 1 3 3 3 1 Non-repetitive/WGA-negative nucleoporin C-terminal DUF4119 PF13494.6 EGC37329.1 - 0.059 13.5 0.2 2.4 8.3 0.0 2.9 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) DUF4504 PF14953.6 EGC37330.1 - 2.9e-22 79.3 10.2 1e-16 61.1 5.4 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4504) Cyc-maltodext_C PF10438.9 EGC37330.1 - 3.3 7.9 7.4 0.16 12.1 1.0 2.1 3 0 0 3 3 3 0 Cyclo-malto-dextrinase C-terminal domain NIF PF03031.18 EGC37331.1 - 5.1e-20 71.8 2.3 1.7e-19 70.1 2.3 1.9 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase BRCT PF00533.26 EGC37331.1 - 1.5e-11 44.5 0.2 4.4e-11 43.0 0.2 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGC37331.1 - 1.4e-05 24.9 0.0 2.9e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain BRCT_2 PF16589.5 EGC37331.1 - 5.5e-05 23.5 0.1 0.00032 21.0 0.1 2.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain LIG3_BRCT PF16759.5 EGC37331.1 - 0.0046 17.2 0.1 0.017 15.4 0.1 2.0 1 0 0 1 1 1 1 DNA ligase 3 BRCT domain DUF2838 PF10998.8 EGC37332.1 - 9.6e-39 132.1 7.8 9.6e-39 132.1 7.8 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) WD40 PF00400.32 EGC37333.1 - 6.4e-33 112.3 25.2 2.9e-07 31.1 0.2 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37333.1 - 1.6e-16 60.4 6.2 4.5e-05 23.7 0.0 5.7 2 2 3 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain PhyH PF05721.13 EGC37333.1 - 3e-09 37.5 3.1 9e-09 35.9 0.1 3.0 3 1 0 3 3 3 1 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGC37333.1 - 0.0021 16.9 0.0 0.13 11.0 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PNISR PF15996.5 EGC37333.1 - 6 7.1 19.4 0.93 9.7 15.2 1.8 2 0 0 2 2 2 0 Arginine/serine-rich protein PNISR COMM_domain PF07258.14 EGC37334.1 - 2e-20 72.7 2.5 2e-20 72.7 2.5 1.7 2 0 0 2 2 2 1 COMM domain Beta-lactamase PF00144.24 EGC37335.1 - 3.4e-35 121.9 0.0 7e-21 74.8 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase MID_MedPIWI PF18296.1 EGC37337.1 - 0.019 14.8 2.3 0.022 14.6 2.3 1.0 1 0 0 1 1 1 0 MID domain of medPIWI DUF4834 PF16118.5 EGC37337.1 - 0.23 12.4 2.7 0.27 12.2 2.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) Orf78 PF06024.12 EGC37337.1 - 0.34 11.2 4.9 0.42 10.9 4.9 1.3 1 0 0 1 1 1 0 Orf78 (ac78) Menin PF05053.13 EGC37337.1 - 0.67 8.2 6.9 0.72 8.1 6.9 1.0 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.13 EGC37337.1 - 0.88 10.2 12.9 1.3 9.6 12.9 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.32 EGC37338.1 - 5.9e-61 201.0 25.6 1.1e-09 38.7 0.3 7.9 7 1 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37338.1 - 8.8e-20 70.8 3.0 6.1e-06 26.4 0.0 5.1 2 2 3 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC37338.1 - 9.3e-11 41.1 7.8 0.12 11.0 0.1 5.9 2 2 2 6 6 6 5 Nucleoporin Nup120/160 LisH PF08513.11 EGC37338.1 - 5.4e-07 29.4 0.6 1.1e-06 28.4 0.6 1.5 1 0 0 1 1 1 1 LisH Nucleoporin_N PF08801.11 EGC37338.1 - 0.00017 20.5 0.3 0.066 12.0 0.0 3.3 3 1 1 4 4 4 1 Nup133 N terminal like Ge1_WD40 PF16529.5 EGC37338.1 - 0.0055 15.7 13.0 1.5 7.7 0.7 4.0 2 1 0 3 3 3 3 WD40 region of Ge1, enhancer of mRNA-decapping protein WD40_like PF17005.5 EGC37338.1 - 0.086 12.2 0.2 0.37 10.1 0.1 2.0 2 0 0 2 2 2 0 WD40-like domain RhoGEF PF00621.20 EGC37339.1 - 2.3e-37 129.0 9.9 2.3e-37 129.0 9.9 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC37339.1 - 8e-06 26.3 0.7 3.2e-05 24.4 0.7 2.1 1 0 0 1 1 1 1 PH domain Pallilysin PF18663.1 EGC37339.1 - 0.046 13.7 0.2 0.046 13.7 0.2 3.1 3 0 0 3 3 3 0 Pallilysin beta barrel domain DUF2465 PF10239.9 EGC37340.1 - 1.9e-40 139.1 3.4 2.6e-40 138.6 3.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) FNIP PF05725.12 EGC37341.1 - 1.1e-11 44.7 21.0 4e-08 33.3 1.0 5.9 3 2 1 5 5 5 4 FNIP Repeat LRR_6 PF13516.6 EGC37341.1 - 0.21 11.7 1.8 24 5.3 0.1 3.8 4 0 0 4 4 4 0 Leucine Rich repeat LRR_8 PF13855.6 EGC37341.1 - 0.44 10.3 6.9 0.68 9.7 0.3 3.9 5 0 0 5 5 5 0 Leucine rich repeat LRR_4 PF12799.7 EGC37341.1 - 3.7 8.1 16.0 14 6.3 0.2 4.7 3 2 2 5 5 5 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC37341.1 - 3.9 8.4 7.1 41 5.3 0.1 4.3 3 2 0 3 3 3 0 Leucine Rich Repeat CYSTM PF12734.7 EGC37342.1 - 0.065 13.6 0.1 0.065 13.6 0.1 3.8 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance Pex14_N PF04695.13 EGC37342.1 - 0.19 12.4 8.0 0.25 12.0 8.0 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region GFA PF04828.14 EGC37343.1 - 2.2e-06 27.9 0.1 2.2e-06 27.9 0.1 1.8 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ABC_membrane PF00664.23 EGC37344.1 - 3.9e-59 200.5 19.3 3.9e-59 200.5 19.3 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 EGC37344.1 - 4.5e-37 127.9 3.6 4.5e-37 127.9 3.6 1.8 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.27 EGC37344.1 - 2.5e-33 115.5 0.1 9.2e-33 113.7 0.1 2.1 1 0 0 1 1 1 1 ABC transporter MitMem_reg PF13012.6 EGC37344.1 - 3e-30 104.9 0.3 8.5e-30 103.5 0.3 1.9 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.21 EGC37344.1 - 8.6e-23 80.6 0.0 5.5e-22 77.9 0.0 2.5 3 0 0 3 3 3 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SMC_N PF02463.19 EGC37344.1 - 1.2e-05 24.8 0.2 0.0011 18.4 0.2 2.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC37344.1 - 0.0024 17.6 0.1 0.0069 16.1 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC37344.1 - 0.11 12.4 0.7 0.4 10.6 0.1 2.3 2 0 0 2 2 2 0 RsgA GTPase AAA_23 PF13476.6 EGC37344.1 - 0.14 12.7 0.1 0.14 12.7 0.1 3.2 3 0 0 3 3 3 0 AAA domain AIG1 PF04548.16 EGC37346.1 - 2.6e-09 36.7 1.6 2.6e-09 36.7 1.6 2.7 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.23 EGC37346.1 - 5.9e-09 36.0 0.7 5.9e-09 36.0 0.7 3.0 2 2 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC37346.1 - 0.00014 21.5 0.2 0.00014 21.5 0.2 2.8 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.6 EGC37346.1 - 0.00029 21.1 1.8 0.02 15.2 0.0 2.8 2 1 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGC37346.1 - 0.0011 18.8 0.2 0.0011 18.8 0.2 2.4 2 0 0 2 2 2 1 RsgA GTPase ABC_tran PF00005.27 EGC37346.1 - 0.0019 18.7 0.1 0.0019 18.7 0.1 3.1 2 1 0 2 2 1 1 ABC transporter PhageMin_Tail PF10145.9 EGC37346.1 - 0.0024 17.8 0.0 0.034 14.0 0.0 2.2 1 1 1 2 2 2 1 Phage-related minor tail protein PRK PF00485.18 EGC37346.1 - 0.0026 17.5 0.1 0.0069 16.1 0.1 1.8 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.6 EGC37346.1 - 0.005 17.2 0.0 0.0098 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGC37346.1 - 0.0051 17.2 1.1 0.065 13.6 0.0 3.1 2 0 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 EGC37346.1 - 0.0069 16.1 0.1 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain zinc_ribbon_4 PF13717.6 EGC37346.1 - 0.018 14.9 2.3 0.018 14.9 2.3 5.2 6 0 0 6 6 5 0 zinc-ribbon domain NACHT PF05729.12 EGC37346.1 - 0.019 14.9 0.1 0.34 10.8 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA PF00004.29 EGC37346.1 - 0.03 14.7 1.2 0.79 10.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC37346.1 - 0.11 12.4 0.0 1.1 9.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) T2SSE PF00437.20 EGC37346.1 - 0.14 11.2 0.9 0.34 9.9 0.9 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein Dynamin_N PF00350.23 EGC37346.1 - 0.69 9.9 0.0 0.64 10.1 0.1 6.5 4 1 1 5 5 4 0 Dynamin family DUF951 PF06107.11 EGC37346.1 - 0.78 9.7 10.1 0.4 10.6 0.6 3.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF951) SWIRM PF04433.17 EGC37347.1 - 7e-21 74.4 0.1 7e-21 74.4 0.1 3.4 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.31 EGC37347.1 - 1.5e-19 69.9 3.3 2.4e-10 40.4 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain JAB PF01398.21 EGC37347.1 - 4.9e-13 49.1 0.0 1.9e-12 47.2 0.0 2.0 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.6 EGC37347.1 - 2.1e-07 30.7 0.1 2.6e-06 27.2 0.1 2.2 1 1 1 2 2 2 1 Prokaryotic homologs of the JAB domain Myb_DNA-bind_6 PF13921.6 EGC37347.1 - 4.1e-06 27.0 15.2 9.5e-06 25.8 0.1 4.5 4 1 1 5 5 5 2 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC37347.1 - 0.011 15.6 5.3 0.011 15.6 5.3 4.9 4 1 0 4 4 4 0 Myb DNA-binding like Lactamase_B_6 PF16661.5 EGC37349.1 - 5.3e-23 81.5 0.1 2.2e-22 79.5 0.1 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily domain Beta-Casp PF10996.8 EGC37349.1 - 3.7e-22 78.7 0.0 1.2e-21 77.0 0.0 1.9 2 0 0 2 2 2 1 Beta-Casp domain RMMBL PF07521.12 EGC37349.1 - 3.2e-21 75.0 0.0 6.6e-21 74.0 0.0 1.6 1 0 0 1 1 1 1 Zn-dependent metallo-hydrolase RNA specificity domain Lactamase_B PF00753.27 EGC37349.1 - 9.9e-13 48.5 0.0 9.6e-12 45.3 0.0 2.3 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.7 EGC37349.1 - 6.8e-10 38.8 0.4 2.3e-09 37.1 0.1 1.9 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGC37349.1 - 0.00041 20.3 0.0 0.0033 17.3 0.0 2.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain dNK PF01712.19 EGC37350.1 - 4.5e-53 180.1 0.7 5.4e-53 179.9 0.7 1.0 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.6 EGC37350.1 - 1.1e-10 42.2 0.0 1.6e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.17 EGC37350.1 - 8.8e-08 32.0 0.3 2.7e-05 23.9 0.2 2.3 2 0 0 2 2 2 2 Thymidylate kinase SKI PF01202.22 EGC37350.1 - 0.00016 21.9 0.8 0.038 14.1 0.2 2.3 2 0 0 2 2 2 2 Shikimate kinase AAA_33 PF13671.6 EGC37350.1 - 0.00019 21.6 0.0 0.00041 20.5 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC37350.1 - 0.0013 19.0 0.0 0.0019 18.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain TsaE PF02367.17 EGC37350.1 - 0.0019 18.2 0.1 0.0099 15.9 0.0 2.1 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin2 PF13189.6 EGC37350.1 - 0.0026 17.9 1.0 0.028 14.5 0.6 2.8 1 1 0 1 1 1 1 Cytidylate kinase-like family ABC_tran PF00005.27 EGC37350.1 - 0.0036 17.8 0.0 0.0075 16.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter AAA_17 PF13207.6 EGC37350.1 - 0.0063 16.9 0.7 3.2 8.2 0.1 2.5 3 0 0 3 3 2 2 AAA domain AAA_22 PF13401.6 EGC37350.1 - 0.014 15.6 0.0 0.18 12.0 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.6 EGC37350.1 - 0.019 14.7 0.2 0.2 11.4 0.1 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain CoaE PF01121.20 EGC37350.1 - 0.031 13.9 0.0 0.59 9.8 0.0 2.1 2 0 0 2 2 2 0 Dephospho-CoA kinase Herpes_TK PF00693.18 EGC37350.1 - 0.039 13.2 0.0 0.065 12.5 0.0 1.4 1 0 0 1 1 1 0 Thymidine kinase from herpesvirus ATP_bind_1 PF03029.17 EGC37350.1 - 0.065 13.0 0.5 0.45 10.3 0.0 2.2 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.15 EGC37350.1 - 0.16 11.9 1.3 1.1 9.2 0.2 2.2 2 0 0 2 2 2 0 NTPase Lipase_3 PF01764.25 EGC37351.1 - 3.4e-21 75.6 0.0 2.9e-20 72.6 0.0 2.2 2 0 0 2 2 2 1 Lipase (class 3) DUF2048 PF09752.9 EGC37351.1 - 0.012 14.8 0.0 0.023 13.8 0.0 1.4 1 0 0 1 1 1 0 Abhydrolase domain containing 18 SSP160 PF06933.11 EGC37351.1 - 1.9 6.6 12.7 3.4 5.7 12.7 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CbiC PF02570.15 EGC37352.1 - 0.13 12.0 2.4 0.67 9.6 0.8 2.4 2 0 0 2 2 2 0 Precorrin-8X methylmutase EMP24_GP25L PF01105.24 EGC37353.1 - 1.7e-44 151.9 0.6 2e-44 151.7 0.6 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Interfer-bind PF09294.10 EGC37353.1 - 0.077 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III TFIIS_M PF07500.14 EGC37355.1 - 6e-22 78.2 2.0 6e-22 78.2 2.0 2.2 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.18 EGC37355.1 - 1.9e-19 69.2 9.6 1.9e-19 69.2 9.6 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.11 EGC37355.1 - 1.5e-09 37.8 4.2 1.6e-08 34.4 4.2 2.5 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Flp_N PF03930.14 EGC37355.1 - 0.025 14.6 1.9 1.3 9.0 0.1 2.9 2 1 0 2 2 2 0 Recombinase Flp protein N-terminus DUF4423 PF14394.6 EGC37355.1 - 0.28 10.9 3.6 1.6 8.4 0.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) C1_4 PF07975.12 EGC37355.1 - 2.4 8.5 7.1 2.5 8.4 1.5 2.8 1 1 1 2 2 2 0 TFIIH C1-like domain DnaJ PF00226.31 EGC37356.1 - 3.8e-19 68.6 0.1 7.1e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.27 EGC37356.1 - 1.4e-08 34.5 0.1 0.012 15.5 0.0 2.9 3 0 0 3 3 3 2 Mitochondrial carrier protein VHP PF02209.19 EGC37358.1 - 1.7e-14 53.5 0.4 2.7e-14 52.9 0.4 1.2 1 0 0 1 1 1 1 Villin headpiece domain LSM PF01423.22 EGC37359.1 - 5.8e-19 67.5 1.6 7.6e-19 67.2 1.6 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC37359.1 - 0.015 15.5 0.2 0.023 14.8 0.2 1.4 1 0 0 1 1 1 0 Ataxin 2 SM domain BPL_C PF02237.17 EGC37359.1 - 0.031 14.2 0.4 0.062 13.2 0.4 1.5 1 0 0 1 1 1 0 Biotin protein ligase C terminal domain Gemin7 PF11095.8 EGC37359.1 - 0.039 13.8 0.0 0.053 13.4 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) Tail_tube PF10618.9 EGC37359.1 - 0.1 12.5 0.1 0.15 11.9 0.1 1.2 1 0 0 1 1 1 0 Phage tail tube protein PIF1 PF05970.14 EGC37360.1 - 1.5e-10 40.8 0.1 1.5e-10 40.8 0.1 2.4 3 0 0 3 3 2 1 PIF1-like helicase AAA_30 PF13604.6 EGC37360.1 - 1.3e-06 28.2 0.0 1.9e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGC37360.1 - 1.9e-06 27.5 2.6 4.8e-05 22.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGC37360.1 - 0.00075 18.9 0.0 0.0018 17.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI T2SSE PF00437.20 EGC37360.1 - 0.0022 17.1 0.1 0.004 16.2 0.1 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein PhoH PF02562.16 EGC37360.1 - 0.0024 17.3 0.0 0.0058 16.1 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein NACHT PF05729.12 EGC37360.1 - 0.0058 16.6 0.0 0.01 15.8 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.6 EGC37360.1 - 0.0096 16.3 0.0 0.014 15.7 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain DUF2075 PF09848.9 EGC37360.1 - 0.01 15.1 0.1 0.01 15.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) ResIII PF04851.15 EGC37360.1 - 0.014 15.4 0.1 0.014 15.4 0.1 3.0 1 1 1 2 2 1 0 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGC37360.1 - 0.021 15.2 0.0 0.04 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain DEAD PF00270.29 EGC37360.1 - 0.022 14.5 0.0 0.049 13.4 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase AAA_22 PF13401.6 EGC37360.1 - 0.029 14.7 0.1 0.069 13.4 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGC37360.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.6 2 0 0 2 2 1 0 AAA domain Macoilin PF09726.9 EGC37360.1 - 0.54 8.7 13.9 0.56 8.7 13.9 1.1 1 0 0 1 1 1 0 Macoilin family Dfp1_Him1_M PF08630.10 EGC37360.1 - 2.4 8.4 11.0 1.6 9.0 8.3 1.9 1 1 1 2 2 2 0 Dfp1/Him1, central region Presenilin PF01080.17 EGC37360.1 - 5.6 5.6 10.4 7.1 5.3 10.4 1.2 1 0 0 1 1 1 0 Presenilin Dicty_CTDC PF00526.18 EGC37361.1 - 4.2e-08 33.0 120.6 1.1e-05 25.2 4.5 12.1 12 0 0 12 12 12 7 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC37361.1 - 1.3e-05 25.0 0.2 2.4e-05 24.2 0.2 1.5 1 0 0 1 1 1 1 PA14 domain C2-C2_1 PF11618.8 EGC37361.1 - 0.16 12.0 0.3 0.29 11.2 0.3 1.3 1 0 0 1 1 1 0 First C2 domain of RPGR-interacting protein 1 Mss4 PF04421.13 EGC37362.1 - 4e-18 65.3 1.4 5.9e-18 64.8 0.3 1.8 2 0 0 2 2 2 1 Mss4 protein Yippee-Mis18 PF03226.14 EGC37362.1 - 0.063 13.5 3.8 0.97 9.7 3.8 2.2 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Ribosomal_L14e PF01929.17 EGC37364.1 - 9.4e-19 67.7 2.3 2.9e-18 66.1 2.3 1.9 1 0 0 1 1 1 1 Ribosomal protein L14 TPR_14 PF13428.6 EGC37364.1 - 4.5e-10 39.5 0.2 0.16 12.8 0.0 7.6 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_15 PF13429.6 EGC37364.1 - 9e-08 31.7 3.3 0.00045 19.5 0.0 4.6 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC37364.1 - 2e-06 28.0 0.1 0.092 13.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat Suf PF05843.14 EGC37364.1 - 4.4e-06 26.9 41.9 0.11 12.5 0.1 7.7 2 2 4 6 6 6 4 Suppressor of forked protein (Suf) Mad3_BUB1_I PF08311.12 EGC37364.1 - 4.8e-06 26.6 19.0 0.15 12.0 0.0 7.2 7 2 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGC37364.1 - 3.4e-05 23.6 1.5 0.0085 16.1 0.1 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC37364.1 - 5.1e-05 23.7 0.8 5.1 7.7 0.0 4.9 5 1 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37364.1 - 0.00012 22.0 3.9 0.14 12.5 0.2 5.3 4 0 0 4 4 4 1 Tetratricopeptide repeat FAT PF02259.23 EGC37364.1 - 0.00039 19.7 1.8 1.2 8.2 0.1 3.4 3 0 0 3 3 3 2 FAT domain TPR_1 PF00515.28 EGC37364.1 - 0.016 15.0 1.4 0.64 9.9 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC37364.1 - 0.05 13.6 0.1 1.5 9.1 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat HEPN_Swt1 PF18731.1 EGC37364.1 - 0.17 12.2 4.0 2.1 8.7 0.2 3.4 3 0 0 3 3 3 0 Swt1-like HEPN HAT PF02184.16 EGC37364.1 - 2.9 7.9 9.8 1.6 8.8 0.2 4.9 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat FNIP PF05725.12 EGC37365.1 - 1.3e-66 220.5 84.9 4.8e-06 26.6 1.6 17.0 3 2 21 24 24 24 24 FNIP Repeat zf-B_box PF00643.24 EGC37365.1 - 0.0002 21.4 5.3 0.00035 20.7 5.3 1.4 1 0 0 1 1 1 1 B-box zinc finger PKD PF00801.20 EGC37365.1 - 0.061 13.2 0.3 30 4.6 0.0 5.1 6 1 0 6 6 6 0 PKD domain zf-UBR PF02207.20 EGC37365.1 - 0.24 11.6 1.8 0.47 10.6 1.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) LRR_2 PF07723.13 EGC37365.1 - 0.55 11.0 8.6 27 5.6 0.0 7.2 9 0 0 9 9 9 0 Leucine Rich Repeat polyprenyl_synt PF00348.17 EGC37367.1 - 1e-68 231.2 0.0 1.3e-68 230.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase SWI2_SNF2 PF18766.1 EGC37368.1 - 1.3e-18 67.5 0.7 1.3e-18 67.5 0.7 3.0 2 1 0 2 2 2 1 SWI2/SNF2 ATPase AAA_33 PF13671.6 EGC37369.1 - 8.6e-05 22.7 0.0 0.00026 21.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC37369.1 - 0.00073 20.1 0.2 0.0013 19.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC37369.1 - 0.011 16.0 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC37369.1 - 0.14 11.4 0.0 0.29 10.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin CdiA_C_tRNase PF18664.1 EGC37369.1 - 2.2 8.5 7.8 3.5 7.9 0.2 2.4 1 1 1 2 2 2 0 CdiA C-terminal tRNase domain MinC_C PF03775.16 EGC37370.1 - 2.5e-25 88.4 0.1 4.6e-25 87.6 0.1 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain MinC_N PF05209.13 EGC37370.1 - 1.7e-13 50.4 0.2 3.2e-13 49.5 0.2 1.4 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain RNA_pol_Rpb8 PF03870.15 EGC37371.1 - 2.4e-48 163.9 0.1 2.7e-48 163.7 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 RNA_pol_RpbG PF16992.5 EGC37371.1 - 0.0015 18.6 0.1 0.008 16.2 0.0 1.8 2 0 0 2 2 2 1 DNA-directed RNA polymerase, subunit G Acetyltransf_10 PF13673.7 EGC37372.1 - 0.00067 19.6 0.1 0.012 15.5 0.1 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC37372.1 - 0.035 14.3 0.1 1.7 8.9 0.1 2.1 1 1 1 2 2 2 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC37372.1 - 0.065 13.7 0.0 1.3 9.5 0.0 2.2 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain SR-25 PF10500.9 EGC37373.1 - 0.0047 16.6 2.1 0.012 15.3 2.1 1.6 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Band_3_cyto PF07565.13 EGC37373.1 - 2.6 7.8 7.4 3 7.6 6.8 1.6 1 1 0 1 1 1 0 Band 3 cytoplasmic domain TM2 PF05154.16 EGC37374.1 - 1.8e-15 57.0 14.4 2.6e-15 56.5 14.4 1.2 1 0 0 1 1 1 1 TM2 domain Cmyb_C PF09316.10 EGC37374.1 - 0.37 10.5 2.5 0.57 9.9 2.5 1.3 1 0 0 1 1 1 0 C-myb, C-terminal MatE PF01554.18 EGC37376.1 - 4.1e-53 179.3 28.5 3.6e-31 108.0 11.5 3.2 4 0 0 4 4 4 2 MatE DUF4233 PF14017.6 EGC37376.1 - 0.01 16.2 1.9 0.01 16.2 1.9 3.9 4 1 0 4 4 4 0 Protein of unknown function (DUF4233) Pox_Ag35 PF03286.14 EGC37376.1 - 4.6 7.0 19.4 4 7.2 17.9 1.6 2 0 0 2 2 2 0 Pox virus Ag35 surface protein zf-LITAF-like PF10601.9 EGC37376.1 - 5.1 7.4 6.4 47 4.3 0.4 3.5 3 0 0 3 3 3 0 LITAF-like zinc ribbon domain HATPase_c PF02518.26 EGC37377.1 - 5.4e-30 104.2 0.5 1.9e-29 102.4 0.5 2.0 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC37377.1 - 1.2e-25 89.8 0.5 1.4e-24 86.4 0.2 2.7 2 1 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.25 EGC37377.1 - 5.9e-17 61.5 0.1 1.5e-16 60.1 0.0 1.8 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGC37377.1 - 7.8e-06 25.8 0.0 1.9e-05 24.6 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGC37377.1 - 0.064 13.2 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 PAS fold DUF2427 PF10348.9 EGC37377.1 - 0.5 10.2 7.2 0.057 13.2 1.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2427) Phlebovirus_G1 PF07243.11 EGC37377.1 - 1.7 6.9 5.8 2.8 6.2 5.8 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DHHC PF01529.20 EGC37378.1 - 1.5e-36 125.5 14.9 1.5e-36 125.5 14.9 2.4 2 0 0 2 2 2 1 DHHC palmitoyltransferase XRN_M PF17846.1 EGC37378.1 - 1.6 7.6 11.8 2.8 6.8 11.8 1.3 1 0 0 1 1 1 0 Xrn1 helical domain Voltage_CLC PF00654.20 EGC37379.1 - 3.6e-112 375.1 16.9 3.6e-112 375.1 16.9 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGC37379.1 - 4.2e-21 75.1 0.4 3.5e-09 37.0 0.0 2.6 2 0 0 2 2 2 2 CBS domain Retinal PF15449.6 EGC37379.1 - 0.48 8.2 3.6 0.65 7.7 3.6 1.1 1 0 0 1 1 1 0 Retinal protein SCAI PF12070.8 EGC37381.1 - 1.3e-213 710.7 33.6 1.3e-213 710.7 33.6 2.9 2 1 0 2 2 2 1 Protein SCAI Profilin PF00235.19 EGC37382.1 - 5.6e-07 29.9 0.0 8.8e-07 29.2 0.0 1.3 1 0 0 1 1 1 1 Profilin YjcQ PF09639.10 EGC37382.1 - 0.00054 20.1 0.6 0.0013 18.9 0.6 1.6 1 0 0 1 1 1 1 YjcQ protein Zip PF02535.22 EGC37382.1 - 0.073 12.3 3.8 0.1 11.8 3.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Strabismus PF06638.11 EGC37382.1 - 0.29 9.7 3.4 0.39 9.3 3.4 1.1 1 0 0 1 1 1 0 Strabismus protein FAM60A PF15396.6 EGC37382.1 - 0.41 10.6 8.5 0.59 10.1 8.5 1.2 1 0 0 1 1 1 0 Protein Family FAM60A PDDEXK_6 PF04720.12 EGC37382.1 - 0.74 9.7 8.6 0.94 9.4 8.6 1.1 1 0 0 1 1 1 0 PDDEXK-like family of unknown function MCM3AP_GANP PF16769.5 EGC37382.1 - 0.82 7.9 5.8 0.98 7.6 5.8 1.0 1 0 0 1 1 1 0 MCM3AP domain of GANP DUF913 PF06025.12 EGC37382.1 - 0.96 8.4 5.0 1.1 8.2 5.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) Presenilin PF01080.17 EGC37382.1 - 1.5 7.5 9.5 1.7 7.3 9.5 1.1 1 0 0 1 1 1 0 Presenilin CDC27 PF09507.10 EGC37382.1 - 1.5 8.1 17.3 2 7.7 17.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Gti1_Pac2 PF09729.9 EGC37382.1 - 1.6 8.8 9.6 2.1 8.4 9.6 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Cwf_Cwc_15 PF04889.12 EGC37382.1 - 1.7 8.3 20.3 2.4 7.9 20.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SID-1_RNA_chan PF13965.6 EGC37382.1 - 1.8 6.9 9.5 2.1 6.6 9.5 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Neuregulin PF02158.15 EGC37382.1 - 2.2 7.6 9.3 2.8 7.2 9.3 1.1 1 0 0 1 1 1 0 Neuregulin intracellular region DUF3381 PF11861.8 EGC37382.1 - 2.5 7.9 24.2 3.6 7.4 24.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3381) SLC12 PF03522.15 EGC37382.1 - 5.7 5.8 11.2 7 5.5 11.2 1.1 1 0 0 1 1 1 0 Solute carrier family 12 MDM10 PF12519.8 EGC37382.1 - 6.5 5.5 9.2 7.8 5.2 9.2 1.1 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 RR_TM4-6 PF06459.12 EGC37382.1 - 7.4 6.3 19.1 10 5.9 19.1 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Ribosomal_L33 PF00471.20 EGC37383.1 - 5.9e-13 49.0 0.5 7.1e-13 48.8 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 V-ATPase_G PF03179.15 EGC37384.1 - 1e-29 103.1 15.2 1.2e-29 103.0 15.2 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit DUF3552 PF12072.8 EGC37384.1 - 0.0011 18.4 11.5 0.0011 18.4 11.5 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) MscS_porin PF12795.7 EGC37384.1 - 0.0035 16.9 8.6 0.0052 16.4 8.6 1.3 1 0 0 1 1 1 1 Mechanosensitive ion channel porin domain ATP-synt_B PF00430.18 EGC37384.1 - 0.0088 16.1 15.9 0.028 14.5 8.6 2.0 1 1 1 2 2 2 1 ATP synthase B/B' CF(0) FliD_N PF02465.18 EGC37384.1 - 0.018 15.8 4.9 0.023 15.4 4.9 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus DivIVA PF05103.13 EGC37384.1 - 0.025 14.7 14.8 0.11 12.6 5.5 2.1 1 1 1 2 2 2 0 DivIVA protein Bacillus_HBL PF05791.11 EGC37384.1 - 0.027 14.3 4.4 0.035 13.9 4.4 1.2 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) ColG_sub PF18496.1 EGC37384.1 - 0.031 14.4 1.1 0.038 14.1 1.1 1.2 1 0 0 1 1 1 0 Collagenase G catalytic helper subdomain Mod_r PF07200.13 EGC37384.1 - 0.035 14.2 9.7 0.1 12.7 9.7 1.7 1 1 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein BAR_3 PF16746.5 EGC37384.1 - 0.035 13.8 7.8 0.041 13.6 7.8 1.0 1 0 0 1 1 1 0 BAR domain of APPL family DUF2408 PF10303.9 EGC37384.1 - 0.053 14.1 5.1 0.061 13.9 5.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2408) DUF4717 PF15838.5 EGC37384.1 - 0.099 12.7 0.8 0.15 12.1 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4717) DUF4407 PF14362.6 EGC37384.1 - 0.11 11.8 12.0 0.21 10.9 11.2 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) Spc7 PF08317.11 EGC37384.1 - 0.12 11.2 12.1 0.15 10.9 12.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF5624 PF18538.1 EGC37384.1 - 0.16 12.1 2.1 0.17 12.0 0.6 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF5624) PCRF PF03462.18 EGC37384.1 - 0.18 11.6 8.7 0.23 11.3 8.7 1.0 1 0 0 1 1 1 0 PCRF domain ISG65-75 PF11727.8 EGC37384.1 - 0.28 10.4 11.3 0.18 11.0 9.2 1.6 1 1 1 2 2 2 0 Invariant surface glycoprotein Csm1_N PF18504.1 EGC37384.1 - 0.31 11.4 12.3 1.1 9.6 6.4 2.2 2 0 0 2 2 2 0 Csm1 N-terminal domain DUF2203 PF09969.9 EGC37384.1 - 0.35 11.6 5.5 0.48 11.2 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RRF PF01765.19 EGC37384.1 - 0.35 10.8 10.5 0.56 10.2 10.5 1.4 1 1 0 1 1 1 0 Ribosome recycling factor DUF4972 PF16342.5 EGC37384.1 - 0.38 10.4 10.8 1 9.1 1.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4972) NAD_binding_5 PF07994.12 EGC37384.1 - 0.38 10.1 3.8 0.47 9.8 3.8 1.1 1 0 0 1 1 1 0 Myo-inositol-1-phosphate synthase FlgM PF04316.13 EGC37384.1 - 0.44 11.0 9.1 0.093 13.1 2.6 2.4 1 1 1 2 2 2 0 Anti-sigma-28 factor, FlgM PEP-utilisers_N PF05524.13 EGC37384.1 - 0.73 10.0 8.2 1.7 8.8 8.2 1.6 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal DUF4570 PF15134.6 EGC37384.1 - 0.8 9.7 7.9 1 9.4 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) V-ATPase_G_2 PF16999.5 EGC37384.1 - 1.2 9.5 13.5 1.8 9.0 13.5 1.3 1 1 0 1 1 1 0 Vacuolar (H+)-ATPase G subunit HrpE PF06188.12 EGC37384.1 - 1.6 8.5 6.0 3.6 7.4 3.9 1.9 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E vATP-synt_E PF01991.18 EGC37384.1 - 1.8 8.0 20.3 9.5 5.6 20.3 1.8 1 1 0 1 1 1 0 ATP synthase (E/31 kDa) subunit XhlA PF10779.9 EGC37384.1 - 2.5 8.4 8.7 0.77 10.0 2.7 2.4 1 1 1 2 2 2 0 Haemolysin XhlA DUF4781 PF16013.5 EGC37384.1 - 4 6.2 6.7 1 8.1 2.9 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4781) CREPT PF16566.5 EGC37384.1 - 6.5 6.9 10.3 2.6 8.2 6.0 1.9 1 1 1 2 2 2 0 Cell-cycle alteration and expression-elevated protein in tumour DUF883 PF05957.13 EGC37384.1 - 7 7.3 8.5 17 6.1 4.6 2.1 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) COX6C PF02937.15 EGC37385.1 - 0.0042 17.2 0.0 0.0042 17.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Dicty_CTDC PF00526.18 EGC37386.1 - 0 1065.5 880.3 6.7e-11 41.9 17.0 44.8 44 1 0 44 44 44 44 Dictyostelium (slime mold) repeat AAA_18 PF13238.6 EGC37387.1 - 2.8e-07 31.1 0.3 2.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGC37387.1 - 0.00013 22.3 0.0 0.00032 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.6 EGC37387.1 - 0.00077 19.6 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain Rad17 PF03215.15 EGC37387.1 - 0.00099 19.1 0.1 0.0018 18.3 0.1 1.4 1 0 0 1 1 1 1 Rad17 P-loop domain KAP_NTPase PF07693.14 EGC37387.1 - 0.0011 18.3 0.0 0.0015 17.9 0.0 1.1 1 0 0 1 1 1 1 KAP family P-loop domain NB-ARC PF00931.22 EGC37387.1 - 0.0018 17.5 0.0 0.0033 16.7 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain AAA_17 PF13207.6 EGC37387.1 - 0.0018 18.7 0.0 0.0057 17.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGC37387.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.3 1 0 0 1 1 1 1 NTPase PRK PF00485.18 EGC37387.1 - 0.0025 17.6 0.0 0.035 13.8 0.0 2.1 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_22 PF13401.6 EGC37387.1 - 0.0025 18.1 0.0 0.004 17.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.29 EGC37387.1 - 0.0054 17.2 0.0 0.011 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC37387.1 - 0.0063 16.9 0.0 0.0081 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 EGC37387.1 - 0.0078 16.1 0.5 0.12 12.3 0.1 2.1 2 0 0 2 2 2 1 Deoxynucleoside kinase MeaB PF03308.16 EGC37387.1 - 0.014 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_5 PF07728.14 EGC37387.1 - 0.016 15.2 0.0 0.046 13.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) KTI12 PF08433.10 EGC37387.1 - 0.021 14.3 0.0 0.032 13.7 0.0 1.3 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_14 PF13173.6 EGC37387.1 - 0.022 14.8 0.3 0.13 12.3 0.0 2.2 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.12 EGC37387.1 - 0.029 13.7 0.0 0.066 12.5 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin ABC_tran PF00005.27 EGC37387.1 - 0.033 14.7 0.0 0.046 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter RuvB_N PF05496.12 EGC37387.1 - 0.033 13.9 0.0 0.056 13.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain RsgA_GTPase PF03193.16 EGC37387.1 - 0.038 13.9 0.1 0.064 13.2 0.1 1.3 1 0 0 1 1 1 0 RsgA GTPase AAA_7 PF12775.7 EGC37387.1 - 0.095 12.2 0.6 0.29 10.6 0.0 2.0 3 0 0 3 3 3 0 P-loop containing dynein motor region Guanylate_kin PF00625.21 EGC37387.1 - 0.095 12.4 0.0 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Guanylate kinase Cytidylate_kin PF02224.18 EGC37387.1 - 0.19 11.4 0.0 0.47 10.1 0.0 1.6 2 0 0 2 2 2 0 Cytidylate kinase Actin PF00022.19 EGC37388.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin SIKE PF05769.11 EGC37389.1 - 0.052 13.5 3.0 0.037 14.0 1.1 1.9 2 1 0 2 2 2 0 SIKE family Syntaxin_2 PF14523.6 EGC37389.1 - 0.075 13.4 1.6 0.29 11.5 0.3 2.3 2 0 0 2 2 2 0 Syntaxin-like protein DUF3045 PF11243.8 EGC37390.1 - 0.013 15.7 0.1 0.016 15.4 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) CM1 PF03026.15 EGC37390.1 - 0.09 12.1 0.0 0.092 12.1 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M1 protein PLDc_2 PF13091.6 EGC37391.1 - 2.3e-35 121.4 0.1 9.3e-20 70.9 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc_3 PF13918.6 EGC37391.1 - 4.6e-33 114.3 0.4 1.1e-30 106.7 0.5 2.3 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGC37391.1 - 8.1e-11 41.6 0.2 1.5e-05 25.0 0.1 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif ANAPC4_WD40 PF12894.7 EGC37392.1 - 2.4e-06 27.8 0.1 0.18 12.2 0.0 3.8 2 2 1 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC37392.1 - 0.00063 20.5 0.1 1.6 9.8 0.0 3.7 4 0 0 4 4 4 2 WD domain, G-beta repeat CPSF_A PF03178.15 EGC37392.1 - 0.027 13.8 0.1 0.45 9.8 0.0 2.0 2 0 0 2 2 2 0 CPSF A subunit region Ge1_WD40 PF16529.5 EGC37392.1 - 0.043 12.8 0.1 0.28 10.1 0.0 2.1 1 1 1 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein DUF1513 PF07433.11 EGC37392.1 - 0.05 12.7 0.0 0.088 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF1548 PF07579.11 EGC37394.1 - 0.035 14.5 0.0 0.038 14.3 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Methyltransf_7 PF03492.15 EGC37396.1 - 1.7e-30 106.4 6.6 2.4e-30 105.9 6.6 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.12 EGC37396.1 - 0.0043 17.7 0.1 0.022 15.4 0.0 2.4 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37396.1 - 0.014 16.1 0.0 0.15 12.8 0.0 2.6 2 2 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGC37396.1 - 0.063 14.0 0.0 0.17 12.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain BRCT_2 PF16589.5 EGC37397.1 - 1.5e-08 34.9 0.7 1.5e-08 34.9 0.7 3.0 3 0 0 3 3 3 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC37397.1 - 4.6e-08 33.3 0.9 2e-07 31.3 0.9 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain RTT107_BRCT_5 PF16770.5 EGC37397.1 - 0.015 15.1 0.4 0.066 13.1 0.1 2.3 2 0 0 2 2 2 0 Regulator of Ty1 transposition protein 107 BRCT domain DEP PF00610.21 EGC37397.1 - 0.035 14.2 0.0 0.08 13.0 0.0 1.5 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) eIF-5_eIF-2B PF01873.17 EGC37399.1 - 2e-39 134.1 0.6 2e-39 134.1 0.6 1.8 2 0 0 2 2 2 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.10 EGC37399.1 - 0.0033 17.7 1.3 0.0033 17.7 1.3 2.5 1 1 1 2 2 2 1 Archaeal TRASH domain TF_Zn_Ribbon PF08271.12 EGC37399.1 - 0.0085 15.6 1.2 0.02 14.4 1.2 1.7 1 0 0 1 1 1 1 TFIIB zinc-binding Mem_trans PF03547.18 EGC37399.1 - 0.21 9.9 2.3 0.25 9.7 2.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Peptidase_S46 PF10459.9 EGC37399.1 - 0.3 9.7 11.1 0.34 9.5 11.1 1.1 1 0 0 1 1 1 0 Peptidase S46 Ndc1_Nup PF09531.10 EGC37399.1 - 0.49 9.0 5.2 0.55 8.9 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Apt1 PF10351.9 EGC37399.1 - 0.87 8.4 16.7 1.1 8.1 16.7 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain XAP5 PF04921.14 EGC37399.1 - 1.5 8.6 18.1 2.5 7.9 18.1 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator Presenilin PF01080.17 EGC37399.1 - 1.7 7.3 18.1 2 7.1 18.1 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC37399.1 - 1.8 6.8 20.0 2.1 6.6 20.0 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2052 PF09747.9 EGC37399.1 - 2.7 8.1 22.5 4.5 7.4 22.5 1.4 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) NPR3 PF03666.13 EGC37399.1 - 4.2 6.1 17.9 6.5 5.4 17.9 1.4 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF763 PF05559.11 EGC37399.1 - 4.4 6.4 7.2 73 2.4 9.8 1.7 2 1 0 2 2 2 0 Protein of unknown function (DUF763) Zip PF02535.22 EGC37399.1 - 5.3 6.2 10.0 6.6 5.9 10.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Dsh_C PF12316.8 EGC37399.1 - 7.8 6.8 10.3 12 6.2 10.3 1.3 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal Actin PF00022.19 EGC37400.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin COesterase PF00135.28 EGC37401.1 - 1.1e-101 341.3 1.7 1.4e-101 340.9 1.7 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC37401.1 - 9e-08 32.2 0.1 2.8e-07 30.6 0.1 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Fungal_lectin PF07938.12 EGC37401.1 - 0.004 16.6 2.5 0.96 8.8 0.3 2.3 1 1 1 2 2 2 2 Fungal fucose-specific lectin Esterase PF00756.20 EGC37401.1 - 0.013 15.2 0.1 0.02 14.6 0.1 1.3 1 0 0 1 1 1 0 Putative esterase tRNA-synt_1b PF00579.25 EGC37402.1 - 1.2e-73 248.0 0.1 4.2e-73 246.2 0.0 1.8 1 1 1 2 2 2 1 tRNA synthetases class I (W and Y) TyrRSs_C PF16714.5 EGC37402.1 - 0.066 13.0 0.1 0.88 9.4 0.1 2.3 2 0 0 2 2 2 0 Tyrosyl-tRNA synthetase C-terminal domain Acetyltransf_6 PF13480.7 EGC37402.1 - 0.22 11.7 0.0 0.4 10.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Pyridoxal_deC PF00282.19 EGC37404.1 - 8.8e-13 47.7 0.0 4.8e-08 32.1 0.0 3.0 3 0 0 3 3 3 2 Pyridoxal-dependent decarboxylase conserved domain DUF5109 PF17134.4 EGC37404.1 - 0.026 14.4 0.1 0.35 10.8 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5109) SapB_2 PF03489.17 EGC37405.1 - 8.6e-21 73.7 15.1 9.9e-12 44.8 4.5 3.2 2 0 0 2 2 2 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC37405.1 - 1.1e-20 73.3 15.7 1.4e-10 40.9 3.8 2.9 2 0 0 2 2 2 2 Saposin-like type B, region 1 Phospholip_A2_3 PF09056.11 EGC37405.1 - 0.0054 17.3 0.2 4.6 7.9 0.1 2.5 2 0 0 2 2 2 2 Prokaryotic phospholipase A2 DUF4239 PF14023.6 EGC37405.1 - 0.064 13.0 0.8 1.2 8.8 0.1 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4239) Uteroglobin PF01099.17 EGC37405.1 - 0.13 12.7 0.2 0.13 12.7 0.2 3.1 1 1 2 4 4 4 0 Uteroglobin family DUF3456 PF11938.8 EGC37405.1 - 0.15 12.5 12.2 1 9.8 2.2 2.9 2 2 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP KaiA PF07688.12 EGC37406.1 - 0.011 15.9 1.1 0.033 14.3 0.1 2.1 1 1 1 2 2 2 0 KaiA C-terminal domain Pinin_SDK_memA PF04696.13 EGC37406.1 - 0.67 10.0 4.4 3.6 7.6 4.4 2.2 1 1 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Complex1_LYR PF05347.15 EGC37407.1 - 4.3e-12 45.9 0.2 5.5e-12 45.5 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC37407.1 - 0.014 16.2 0.1 0.016 16.0 0.1 1.1 1 0 0 1 1 1 0 Complex1_LYR-like IBN_N PF03810.19 EGC37408.1 - 9.7e-11 41.4 0.9 1.3e-09 37.9 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGC37408.1 - 0.0096 16.0 3.2 0.47 10.5 0.1 4.4 4 1 0 4 4 4 1 Exportin 1-like protein NAD_binding_10 PF13460.6 EGC37409.1 - 1.8e-07 31.2 0.0 2.3e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC37409.1 - 7.8e-07 28.8 0.0 1e-06 28.4 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.20 EGC37409.1 - 0.001 19.2 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EGC37409.1 - 0.0011 19.4 0.0 0.0018 18.7 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.15 EGC37409.1 - 0.005 16.0 0.0 0.0079 15.4 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.12 EGC37409.1 - 0.013 14.7 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein NmrA PF05368.13 EGC37409.1 - 0.021 14.4 0.0 0.048 13.2 0.0 1.6 1 0 0 1 1 1 0 NmrA-like family 3Beta_HSD PF01073.19 EGC37409.1 - 0.046 12.7 0.0 0.068 12.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family F_actin_cap_B PF01115.17 EGC37409.1 - 0.055 13.1 0.2 0.08 12.6 0.2 1.2 1 0 0 1 1 1 0 F-actin capping protein, beta subunit HIM1 PF08732.10 EGC37409.1 - 0.099 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 HIM1 DUF4357 PF14267.6 EGC37409.1 - 0.88 9.6 4.9 2 8.4 4.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) NAD_binding_10 PF13460.6 EGC37410.1 - 2.8e-06 27.4 0.0 3.9e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC37410.1 - 2.7e-05 23.7 0.0 3.7e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGC37410.1 - 0.0039 16.4 0.0 0.0059 15.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.24 EGC37410.1 - 0.013 16.0 0.0 0.028 14.9 0.0 1.5 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.13 EGC37410.1 - 0.025 14.1 0.0 0.079 12.5 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.20 EGC37410.1 - 0.027 14.6 0.1 0.061 13.4 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.12 EGC37410.1 - 0.047 12.8 0.0 0.089 11.9 0.0 1.4 1 0 0 1 1 1 0 Male sterility protein 3Beta_HSD PF01073.19 EGC37410.1 - 0.088 11.8 0.0 0.13 11.2 0.0 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family OTU PF02338.19 EGC37411.1 - 7.9e-15 55.5 0.1 1.4e-14 54.7 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease ketoacyl-synt PF00109.26 EGC37413.1 - 5.8e-47 160.4 0.0 1e-46 159.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC37413.1 - 1.3e-39 136.6 0.0 2.2e-39 135.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.10 EGC37413.1 - 6.4e-24 84.9 0.0 1.5e-23 83.7 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC37413.1 - 6.4e-21 74.9 0.0 6.4e-21 74.9 0.0 3.8 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC37413.1 - 2.9e-19 69.4 0.0 4.5e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC37413.1 - 5e-17 62.4 0.1 1.5e-16 60.9 0.1 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension Ketoacyl-synt_C PF02801.22 EGC37413.1 - 4.1e-14 52.6 0.0 3.2e-13 49.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.6 EGC37413.1 - 3.3e-09 37.9 0.0 1e-08 36.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_25 PF13649.6 EGC37413.1 - 4.1e-07 30.6 0.0 3.4e-06 27.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGC37413.1 - 2.3e-06 27.9 0.1 6.9e-06 26.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGC37413.1 - 4e-06 26.7 0.1 9.2e-06 25.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC37413.1 - 1.1e-05 25.9 0.0 4.8e-05 23.9 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC37413.1 - 1.2e-05 24.8 0.0 2.3e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC37413.1 - 3.3e-05 23.8 0.0 7.5e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37413.1 - 9.4e-05 22.2 2.6 0.024 14.4 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_28 PF02636.17 EGC37413.1 - 0.0094 15.6 0.1 0.04 13.6 0.0 2.1 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase GDP_Man_Dehyd PF16363.5 EGC37413.1 - 0.013 14.9 0.3 0.013 14.9 0.3 1.9 2 0 0 2 2 2 0 GDP-mannose 4,6 dehydratase DUF1430 PF07242.11 EGC37413.1 - 0.014 15.7 0.5 0.11 12.8 0.5 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) FNIP PF05725.12 EGC37414.1 - 1.3e-17 63.7 90.0 1.4e-07 31.6 1.4 12.6 6 3 3 10 10 10 8 FNIP Repeat RGS PF00615.19 EGC37415.1 - 1.2e-24 86.9 10.5 1.6e-24 86.5 10.5 1.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain RGS-like PF09128.11 EGC37415.1 - 0.0092 15.7 1.9 0.011 15.5 1.9 1.2 1 0 0 1 1 1 1 Regulator of G protein signalling-like domain FliP PF00813.20 EGC37415.1 - 1.2 8.9 2.7 3.9 7.3 0.6 2.0 1 1 1 2 2 2 0 FliP family RCC1 PF00415.18 EGC37416.1 - 9.9e-61 202.2 11.5 8.3e-14 51.9 0.0 9.2 8 2 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC37416.1 - 5.8e-48 159.8 31.1 1.2e-08 34.5 2.9 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.18 EGC37416.1 - 3.6e-46 157.5 2.9 3.6e-46 157.5 2.9 2.5 3 0 0 3 3 3 1 Rab-GTPase-TBC domain TBCC_N PF16752.5 EGC37416.1 - 0.014 15.8 4.6 0.014 15.8 4.6 2.8 2 1 0 2 2 2 0 Tubulin-specific chaperone C N-terminal domain SUKH_6 PF14568.6 EGC37416.1 - 0.05 14.0 6.9 0.15 12.5 0.2 4.3 4 0 0 4 4 4 0 SMI1-KNR4 cell-wall MPS2 PF17060.5 EGC37417.1 - 0.038 13.3 0.0 0.065 12.5 0.0 1.3 1 0 0 1 1 1 0 Monopolar spindle protein 2 Exo_endo_phos PF03372.23 EGC37417.1 - 0.073 12.6 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.32 EGC37419.1 - 2e-18 66.4 8.9 0.26 12.2 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37419.1 - 1.6e-07 31.5 0.0 0.0014 18.9 0.0 4.3 1 1 2 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BBS2_Mid PF14783.6 EGC37419.1 - 0.00015 21.8 0.2 0.74 9.9 0.0 2.9 2 1 1 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.16 EGC37419.1 - 0.00019 20.1 0.4 0.37 9.3 0.1 2.4 3 0 0 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.11 EGC37419.1 - 0.0022 17.9 0.1 1.2 9.0 0.0 2.9 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ PF01011.21 EGC37419.1 - 0.0092 15.9 0.1 2.9 8.0 0.0 2.9 3 0 0 3 3 2 1 PQQ enzyme repeat Nup160 PF11715.8 EGC37419.1 - 0.0095 14.6 0.0 2 7.0 0.0 2.8 1 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_3 PF13570.6 EGC37419.1 - 0.02 15.4 0.0 28 5.4 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain Frtz PF11768.8 EGC37419.1 - 0.031 12.6 0.1 0.59 8.4 0.1 2.3 1 1 0 3 3 3 0 WD repeat-containing and planar cell polarity effector protein Fritz PHTB1_N PF14727.6 EGC37419.1 - 0.041 13.3 0.1 0.51 9.6 0.0 2.2 1 1 1 2 2 2 0 PTHB1 N-terminus Ge1_WD40 PF16529.5 EGC37419.1 - 0.078 11.9 0.0 1.5 7.7 0.0 2.7 2 1 0 2 2 2 0 WD40 region of Ge1, enhancer of mRNA-decapping protein Nop14 PF04147.12 EGC37419.1 - 0.087 11.0 25.5 0.12 10.6 25.5 1.1 1 0 0 1 1 1 0 Nop14-like family DUF2415 PF10313.9 EGC37419.1 - 0.093 12.7 0.1 7.1 6.7 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) Drc1-Sld2 PF11719.8 EGC37419.1 - 0.29 10.7 13.7 0.39 10.2 13.7 1.1 1 0 0 1 1 1 0 DNA replication and checkpoint protein SDA1 PF05285.12 EGC37419.1 - 0.5 9.8 25.3 0.75 9.2 25.3 1.2 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGC37419.1 - 0.54 9.6 25.8 0.82 8.9 25.8 1.1 1 0 0 1 1 1 0 BUD22 Cwf_Cwc_15 PF04889.12 EGC37419.1 - 1.1 8.9 20.4 1.8 8.2 20.4 1.3 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Nop53 PF07767.11 EGC37419.1 - 4.3 6.6 19.7 6.5 6.0 19.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Merozoite_SPAM PF07133.11 EGC37419.1 - 4.3 7.3 28.3 7.8 6.4 28.3 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) CDC45 PF02724.14 EGC37419.1 - 4.6 5.4 23.9 6.5 4.9 23.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltr_RsmB-F PF01189.17 EGC37420.1 - 1.3e-38 132.6 0.0 1.9e-35 122.3 0.0 3.2 1 1 0 1 1 1 1 16S rRNA methyltransferase RsmB/F FtsJ PF01728.19 EGC37420.1 - 0.0061 16.7 0.0 0.012 15.8 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase SSP160 PF06933.11 EGC37420.1 - 2.4 6.3 10.1 3.5 5.7 10.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pinin_SDK_memA PF04696.13 EGC37421.1 - 1.3e-23 83.4 17.9 1.3e-23 83.4 17.9 3.4 2 2 1 3 3 3 1 pinin/SDK/memA/ protein conserved region Glyco_hydro_18 PF00704.28 EGC37422.1 - 7.6e-39 134.3 0.1 1e-38 133.8 0.1 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 PDZ_3 PF17815.1 EGC37423.1 - 0.096 12.5 0.2 0.11 12.4 0.2 1.1 1 0 0 1 1 1 0 PDZ domain adh_short PF00106.25 EGC37425.1 - 2.4e-36 125.1 0.0 3.1e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37425.1 - 1.1e-28 100.5 0.0 1.3e-28 100.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC37425.1 - 6.5e-07 29.4 0.0 8.6e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC37425.1 - 0.0014 18.1 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGC37425.1 - 0.0041 16.6 0.1 0.0063 16.0 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC37425.1 - 0.0064 15.9 0.1 0.0092 15.4 0.1 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Streptin-Immun PF11083.8 EGC37425.1 - 0.075 13.4 0.4 0.075 13.4 0.4 3.0 3 1 0 3 3 3 0 Lantibiotic streptin immunity protein adh_short PF00106.25 EGC37426.1 - 1e-39 136.1 0.0 1.4e-39 135.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37426.1 - 9.3e-28 97.4 0.0 1.2e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC37426.1 - 2.7e-05 24.2 0.0 3.9e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGC37426.1 - 0.0045 16.4 0.1 0.0065 15.9 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC37426.1 - 0.036 13.5 0.0 0.053 13.0 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family Phage_holin_2_1 PF04971.12 EGC37426.1 - 0.16 12.0 0.5 0.47 10.5 0.1 2.0 2 0 0 2 2 2 0 Bacteriophage P21 holin S Pkinase PF00069.25 EGC37427.1 - 1.9e-54 184.8 2.5 3.3e-54 184.0 2.5 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37427.1 - 2.6e-25 89.2 0.3 1.2e-23 83.8 0.1 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC37427.1 - 0.0057 15.5 0.2 0.0095 14.7 0.2 1.3 1 0 0 1 1 1 1 Fungal protein kinase ABC1 PF03109.16 EGC37427.1 - 0.02 15.1 0.0 0.057 13.6 0.0 1.8 1 0 0 1 1 1 0 ABC1 family Choline_kinase PF01633.20 EGC37427.1 - 0.022 14.4 1.0 0.043 13.4 1.0 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.23 EGC37427.1 - 0.04 13.8 0.0 0.065 13.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1196 PF06709.11 EGC37427.1 - 0.048 13.8 0.7 0.11 12.7 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) CDC27 PF09507.10 EGC37428.1 - 2.4e-19 70.1 30.2 2.4e-19 70.1 30.2 4.2 1 1 4 5 5 5 2 DNA polymerase subunit Cdc27 MOZ_SAS PF01853.18 EGC37429.1 - 2.9e-67 225.8 0.8 6.1e-66 221.5 0.8 2.4 1 1 0 1 1 1 1 MOZ/SAS family zf-MYST PF17772.1 EGC37429.1 - 7.5e-27 92.7 3.1 7.5e-27 92.7 3.1 2.1 2 0 0 2 2 2 1 MYST family zinc finger domain Tudor-knot PF11717.8 EGC37429.1 - 1.1e-20 73.3 3.0 2.8e-20 72.0 3.0 1.8 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Acetyltransf_7 PF13508.7 EGC37429.1 - 0.022 15.2 0.0 0.046 14.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC37429.1 - 0.29 11.4 0.0 0.29 11.4 0.0 2.6 2 1 1 3 3 3 0 Acetyltransferase (GNAT) family zf-CXXC PF02008.20 EGC37429.1 - 1.8 8.7 3.8 4.6 7.3 3.8 1.7 1 0 0 1 1 1 0 CXXC zinc finger domain RRM_1 PF00076.22 EGC37430.1 - 2.9e-16 59.1 0.0 3.9e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC37430.1 - 7e-05 22.9 0.0 0.00017 21.6 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGC37430.1 - 0.0016 18.4 0.0 0.0029 17.6 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGC37430.1 - 0.04 14.1 0.0 0.28 11.4 0.0 1.9 1 1 1 2 2 2 0 Cytosolic domain of 10TM putative phosphate transporter DUF4060 PF13269.6 EGC37430.1 - 0.099 12.7 0.0 0.2 11.7 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4060) Es2 PF09751.9 EGC37430.1 - 0.28 10.9 0.0 0.28 10.9 0.0 1.0 1 0 0 1 1 1 0 Nuclear protein Es2 LMBR1 PF04791.16 EGC37431.1 - 1.6 7.5 4.3 2.4 7.0 4.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Ank_5 PF13857.6 EGC37432.1 - 0.17 12.2 3.4 59 4.1 1.3 4.1 3 1 1 4 4 4 0 Ankyrin repeats (many copies) Nudc_N PF14050.6 EGC37432.1 - 1.1 9.3 6.0 16 5.6 0.9 2.9 2 0 0 2 2 2 0 N-terminal conserved domain of Nudc. Erg28 PF03694.13 EGC37434.1 - 1.3e-30 106.0 0.4 1.5e-30 105.8 0.4 1.0 1 0 0 1 1 1 1 Erg28 like protein TLD PF07534.16 EGC37435.1 - 3e-31 108.5 0.2 4.5e-31 107.9 0.2 1.3 1 0 0 1 1 1 1 TLD Coiled PF05710.12 EGC37437.1 - 0.0055 17.5 3.2 0.0065 17.3 3.2 1.1 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC37438.1 - 0.00074 20.3 6.4 0.00079 20.2 6.4 1.1 1 0 0 1 1 1 1 Coiled coil FIBP PF05427.11 EGC37439.1 - 6.7e-70 236.2 2.6 4.7e-57 193.9 1.6 2.0 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) zf-TRAF PF02176.18 EGC37440.1 - 1.4e-06 28.8 9.3 1.4e-06 28.8 9.3 4.5 4 1 0 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC37440.1 - 0.00017 21.4 7.5 0.00017 21.4 7.5 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37440.1 - 0.009 16.0 8.8 0.009 16.0 8.8 3.4 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC37440.1 - 0.015 15.2 7.7 0.015 15.2 7.7 3.2 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) CbtA_toxin PF06755.12 EGC37440.1 - 0.016 15.2 0.0 0.045 13.8 0.0 1.7 1 0 0 1 1 1 0 CbtA_toxin of type IV toxin-antitoxin system Fzo_mitofusin PF04799.13 EGC37440.1 - 0.46 10.0 4.2 2.7 7.5 4.2 2.1 1 1 0 1 1 1 0 fzo-like conserved region zf-C3HC4_3 PF13920.6 EGC37441.1 - 9e-07 28.7 12.8 9e-07 28.7 12.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37441.1 - 0.00076 19.3 12.0 0.00076 19.3 12.0 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC37441.1 - 0.00092 19.5 12.8 0.00092 19.5 12.8 3.4 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.6 EGC37441.1 - 0.028 14.4 12.6 0.028 14.4 12.6 2.7 2 0 0 2 2 2 0 zinc-RING finger domain DZR PF12773.7 EGC37441.1 - 0.06 13.4 16.3 1.3 9.1 11.0 3.5 2 1 0 2 2 2 0 Double zinc ribbon DUF2205 PF10224.9 EGC37441.1 - 0.1 12.6 0.9 0.4 10.7 0.4 2.3 2 1 0 2 2 2 0 Short coiled-coil protein RabGAP-TBC PF00566.18 EGC37442.1 - 1.9e-26 93.0 5.3 1.9e-26 93.0 5.3 2.3 2 1 1 3 3 3 1 Rab-GTPase-TBC domain TMEM238 PF15125.6 EGC37442.1 - 8.3 6.7 8.5 2.4 8.4 0.4 2.3 2 0 0 2 2 2 0 TMEM238 protein family RasGAP PF00616.19 EGC37443.1 - 3.1e-29 102.2 0.1 3.9e-20 72.5 0.1 4.1 3 2 1 4 4 4 2 GTPase-activator protein for Ras-like GTPase BAR_3 PF16746.5 EGC37443.1 - 6.2e-09 35.9 17.4 6.2e-09 35.9 17.4 2.4 2 0 0 2 2 2 1 BAR domain of APPL family BAR PF03114.18 EGC37443.1 - 5e-06 26.3 9.7 5e-06 26.3 9.7 2.6 2 2 0 1 1 1 1 BAR domain DUF2383 PF09537.10 EGC37443.1 - 0.016 15.5 0.4 0.19 12.1 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF2383) CENP-H PF05837.12 EGC37443.1 - 6.5 7.2 10.5 9.9 6.6 2.2 3.5 3 0 0 3 3 3 0 Centromere protein H (CENP-H) Rap_GAP PF02145.15 EGC37444.1 - 3.4e-38 131.1 6.1 3.4e-38 131.1 6.1 2.1 2 0 0 2 2 2 1 Rap/ran-GAP PH_15 PF17339.2 EGC37444.1 - 0.28 11.1 1.7 0.54 10.2 0.2 2.2 2 0 0 2 2 2 0 PH domain Roughex PF06020.11 EGC37444.1 - 0.87 8.6 4.5 1.5 7.8 4.5 1.3 1 0 0 1 1 1 0 Drosophila roughex protein OST_IS PF18246.1 EGC37444.1 - 0.93 9.8 3.6 0.84 10.0 0.2 2.7 3 1 0 3 3 3 0 Oligosaccharyltransferase Insert domain SulA PF03846.14 EGC37446.1 - 0.0015 18.5 0.1 0.0068 16.3 0.0 1.9 2 0 0 2 2 2 1 Cell division inhibitor SulA Staphopain_pro PF14731.6 EGC37446.1 - 0.081 12.9 0.9 3.3 7.7 0.1 2.4 1 1 1 2 2 2 0 Staphopain proregion Ribosomal_L4 PF00573.22 EGC37447.1 - 6.6e-52 176.0 1.2 8.2e-52 175.7 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family AAA_19 PF13245.6 EGC37447.1 - 0.09 13.1 0.0 0.15 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain Ribosomal_L6 PF00347.23 EGC37449.1 - 4.6e-25 88.1 0.6 3.9e-15 56.3 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pyridox_oxase_2 PF12766.7 EGC37449.1 - 0.079 13.6 0.0 0.13 12.9 0.0 1.5 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-CCHC PF00098.23 EGC37450.1 - 1.7e-05 24.6 4.3 4.7e-05 23.3 4.3 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.6 EGC37450.1 - 0.097 12.7 1.2 0.26 11.3 1.2 1.7 1 0 0 1 1 1 0 Zinc knuckle USP19_linker PF16602.5 EGC37450.1 - 0.17 12.4 0.1 0.39 11.3 0.1 1.5 1 0 0 1 1 1 0 Linker region of USP19 deubiquitinase zf-CCHC_2 PF13696.6 EGC37450.1 - 0.42 10.5 4.0 0.88 9.4 4.0 1.6 1 0 0 1 1 1 0 Zinc knuckle SKI PF01202.22 EGC37452.1 - 1.1e-14 54.9 0.0 1.6e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.6 EGC37452.1 - 5.3e-10 40.0 0.1 1.2e-09 38.8 0.0 1.5 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.6 EGC37452.1 - 2.3e-05 24.6 0.0 3.7e-05 23.9 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.6 EGC37452.1 - 0.00051 20.5 0.0 0.0018 18.7 0.0 1.8 1 1 1 2 2 2 1 AAA domain Cytidylate_kin PF02224.18 EGC37452.1 - 0.00053 19.8 0.0 0.0011 18.8 0.0 1.5 2 0 0 2 2 2 1 Cytidylate kinase APS_kinase PF01583.20 EGC37452.1 - 0.0011 18.9 0.0 0.0015 18.5 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Cytidylate_kin2 PF13189.6 EGC37452.1 - 0.0057 16.8 0.0 0.0099 16.0 0.0 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_22 PF13401.6 EGC37452.1 - 0.0081 16.4 0.2 0.015 15.6 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC37452.1 - 0.0086 16.5 0.0 0.012 16.0 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain dNK PF01712.19 EGC37452.1 - 0.0088 15.9 0.1 0.38 10.6 0.1 2.1 1 1 1 2 2 2 1 Deoxynucleoside kinase NB-ARC PF00931.22 EGC37452.1 - 0.011 15.0 0.1 0.02 14.1 0.1 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA PF00004.29 EGC37452.1 - 0.012 16.0 0.7 0.02 15.3 0.7 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.18 EGC37452.1 - 0.012 14.9 0.9 0.024 13.9 0.1 2.0 2 1 0 2 2 2 0 6-phosphofructo-2-kinase AAA_24 PF13479.6 EGC37452.1 - 0.013 15.2 0.6 0.047 13.4 0.3 1.9 1 1 1 2 2 2 0 AAA domain Thymidylate_kin PF02223.17 EGC37452.1 - 0.014 15.1 0.3 0.83 9.3 0.1 2.1 2 0 0 2 2 2 0 Thymidylate kinase NACHT PF05729.12 EGC37452.1 - 0.023 14.6 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.27 EGC37452.1 - 0.044 14.3 1.6 0.049 14.1 1.4 1.3 1 1 0 1 1 1 0 ABC transporter G-alpha PF00503.20 EGC37452.1 - 0.044 12.9 3.0 0.13 11.3 3.0 1.9 1 1 0 1 1 1 0 G-protein alpha subunit AAA_29 PF13555.6 EGC37452.1 - 0.056 13.2 0.2 0.13 12.1 0.2 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2075 PF09848.9 EGC37452.1 - 0.068 12.4 0.0 0.085 12.1 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_14 PF13173.6 EGC37452.1 - 0.068 13.2 0.3 0.28 11.2 0.0 2.1 1 1 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGC37452.1 - 0.07 13.5 0.2 0.21 11.9 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC37452.1 - 0.078 13.2 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain ATPase_2 PF01637.18 EGC37452.1 - 0.088 12.7 0.9 0.19 11.6 0.9 1.9 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea CPT PF07931.12 EGC37452.1 - 0.091 12.6 0.0 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein CM_2 PF01817.21 EGC37452.1 - 0.12 12.8 0.0 0.7 10.3 0.0 2.1 2 1 0 2 2 2 0 Chorismate mutase type II TsaE PF02367.17 EGC37452.1 - 0.15 12.0 0.0 0.27 11.2 0.0 1.4 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF489 PF04356.12 EGC37452.1 - 0.17 11.9 0.0 0.27 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Zeta_toxin PF06414.12 EGC37452.1 - 0.17 11.2 0.0 0.26 10.6 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_30 PF13604.6 EGC37452.1 - 0.19 11.5 0.0 0.31 10.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain PBP PF01161.20 EGC37453.1 - 9.7e-17 61.5 0.0 1.2e-16 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Mitoc_mL59 PF18126.1 EGC37454.1 - 0.00031 21.0 2.3 0.00031 21.0 2.3 2.9 1 1 1 2 2 2 1 Mitochondrial ribosomal protein mL59 DIOX_N PF14226.6 EGC37455.1 - 1.9e-30 106.1 0.0 2.7e-30 105.5 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC37455.1 - 8.6e-23 80.7 0.0 1.8e-22 79.7 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G-alpha PF00503.20 EGC37456.1 - 9.2e-120 400.0 8.1 1.1e-119 399.8 8.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC37456.1 - 2.1e-15 56.6 1.6 8.5e-12 44.9 0.2 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC37456.1 - 0.00099 18.5 5.7 0.046 13.1 0.5 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGC37456.1 - 0.011 15.9 2.4 1.6 9.0 0.1 2.6 2 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Hyccin PF09790.9 EGC37457.1 - 3.1e-40 138.2 9.3 3.1e-40 138.2 9.3 1.7 2 0 0 2 2 2 1 Hyccin RecG_wedge PF17191.4 EGC37457.1 - 0.059 13.0 1.0 20 4.8 0.0 3.2 3 0 0 3 3 3 0 RecG wedge domain NLE PF08154.12 EGC37458.1 - 5.8 7.5 8.3 1.2 9.8 0.4 3.4 3 0 0 3 3 3 0 NLE (NUC135) domain L51_S25_CI-B8 PF05047.16 EGC37460.1 - 2.3e-06 27.4 0.1 5.6e-06 26.2 0.0 1.7 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Asparaginase_2 PF01112.18 EGC37461.1 - 3.7e-36 124.7 0.0 2e-23 82.9 0.0 2.9 2 1 0 2 2 2 2 Asparaginase Glycoprot_B_PH2 PF17417.2 EGC37461.1 - 2.2 8.7 7.1 0.26 11.7 0.9 2.6 2 0 0 2 2 2 0 Herpesvirus Glycoprotein B PH-like domain Mito_carr PF00153.27 EGC37462.1 - 1.5e-74 246.0 0.1 3.6e-25 87.7 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.6 EGC37462.1 - 4.1e-23 81.6 10.9 6.9e-10 39.2 1.1 4.4 3 1 2 5 5 5 5 EF-hand domain pair EF-hand_1 PF00036.32 EGC37462.1 - 1.5e-20 71.2 16.6 1.7e-06 27.1 0.1 6.4 7 0 0 7 7 7 4 EF hand EF-hand_6 PF13405.6 EGC37462.1 - 2.7e-19 67.4 17.6 7.2e-06 25.5 0.3 6.7 6 0 0 6 6 6 4 EF-hand domain EF-hand_8 PF13833.6 EGC37462.1 - 2.1e-16 59.5 10.0 0.0001 22.1 0.8 4.2 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.6 EGC37462.1 - 2e-11 42.9 9.9 0.0012 18.3 0.1 4.4 5 0 0 5 5 5 3 EF hand EF-hand_4 PF12763.7 EGC37462.1 - 0.00055 19.9 3.0 0.054 13.4 0.1 3.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand p25-alpha PF05517.12 EGC37462.1 - 0.064 13.4 11.4 0.83 9.8 1.4 3.6 3 0 0 3 3 3 0 p25-alpha EF-hand_9 PF14658.6 EGC37462.1 - 0.082 13.2 0.5 22 5.5 0.0 3.7 3 1 0 3 3 3 0 EF-hand domain BCNT PF07572.12 EGC37462.1 - 0.12 12.5 0.8 1.2 9.2 0.2 2.7 2 0 0 2 2 2 0 Bucentaur or craniofacial development Tail_VII PF17091.5 EGC37462.1 - 6 6.8 8.1 21 5.1 0.6 3.1 3 0 0 3 3 3 0 Inovirus G7P protein EF-hand_14 PF17959.1 EGC37462.1 - 7.5 7.0 6.2 68 3.9 0.0 4.5 5 0 0 5 5 5 0 EF-hand domain Cytochrom_B561 PF03188.16 EGC37463.1 - 5.5e-14 52.5 10.6 5.5e-14 52.5 10.6 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DOMON PF03351.17 EGC37463.1 - 1.5e-13 51.1 0.4 2.6e-13 50.3 0.4 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.9 EGC37463.1 - 0.009 15.8 12.2 0.25 11.1 7.3 3.3 1 1 2 3 3 3 2 Domain of unknown function (DUF2427) DUF1634 PF07843.11 EGC37463.1 - 0.22 11.6 4.3 12 6.0 4.3 2.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1634) DUF2569 PF10754.9 EGC37463.1 - 0.37 11.2 7.7 0.32 11.4 5.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2569) DUF4231 PF14015.6 EGC37463.1 - 0.63 10.5 8.1 24 5.5 4.0 3.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4231) BaxI_1 PF12811.7 EGC37463.1 - 0.78 9.2 11.2 0.087 12.4 5.4 2.0 1 1 1 2 2 2 0 Bax inhibitor 1 like MgtC PF02308.16 EGC37463.1 - 1.1 9.6 5.5 1.1 9.6 1.2 2.4 2 0 0 2 2 2 0 MgtC family PepSY_TM PF03929.16 EGC37463.1 - 1.4 8.5 4.8 1.6 8.3 3.8 1.5 1 1 0 1 1 1 0 PepSY-associated TM region DUF420 PF04238.12 EGC37463.1 - 2.7 8.3 13.8 3.4 8.0 7.2 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF420) EGF_2 PF07974.13 EGC37465.1 - 7.2e-06 26.3 27.4 0.015 15.6 9.7 2.7 2 0 0 2 2 2 2 EGF-like domain DUF4387 PF14330.6 EGC37465.1 - 0.013 16.2 0.7 5.9 7.7 0.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4387) DUF4562 PF15123.6 EGC37465.1 - 0.053 13.5 0.0 18 5.3 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4562) EGF_Tenascin PF18720.1 EGC37465.1 - 0.5 10.5 13.0 4.4 7.5 2.7 2.9 2 0 0 2 2 2 0 Tenascin EGF domain EGF_2 PF07974.13 EGC37466.1 - 0.0032 17.8 9.7 0.008 16.5 9.7 1.7 1 0 0 1 1 1 1 EGF-like domain Syndecan PF01034.20 EGC37466.1 - 0.02 14.8 1.0 0.047 13.6 1.0 1.6 1 0 0 1 1 1 0 Syndecan domain EGF_Tenascin PF18720.1 EGC37466.1 - 0.85 9.7 2.7 2.4 8.3 2.7 1.8 1 0 0 1 1 1 0 Tenascin EGF domain EGF_2 PF07974.13 EGC37467.1 - 0.0027 18.0 9.7 0.0067 16.8 9.7 1.6 1 0 0 1 1 1 1 EGF-like domain Syndecan PF01034.20 EGC37467.1 - 0.019 14.9 1.0 0.039 13.9 1.0 1.5 1 0 0 1 1 1 0 Syndecan domain EGF_Tenascin PF18720.1 EGC37467.1 - 0.79 9.8 2.7 2 8.6 2.7 1.7 1 0 0 1 1 1 0 Tenascin EGF domain CBS PF00571.28 EGC37469.1 - 1.7e-26 92.4 2.8 2.7e-15 56.5 0.3 2.4 2 0 0 2 2 2 2 CBS domain PRC PF05239.16 EGC37469.1 - 0.0037 17.3 1.5 0.088 12.9 0.0 2.8 3 0 0 3 3 3 1 PRC-barrel domain CbiX PF01903.17 EGC37469.1 - 0.098 13.0 0.0 0.26 11.6 0.0 1.8 2 0 0 2 2 2 0 CbiX Kinesin PF00225.23 EGC37470.1 - 1.7e-102 342.8 0.4 4.1e-58 196.9 0.0 4.3 3 1 1 4 4 4 2 Kinesin motor domain Microtub_bd PF16796.5 EGC37470.1 - 5.8e-27 94.5 0.3 5.8e-27 94.5 0.3 3.5 2 1 1 3 3 3 1 Microtubule binding WD40 PF00400.32 EGC37470.1 - 9.2e-23 80.1 22.4 0.00015 22.5 0.2 7.9 7 0 0 7 7 7 7 WD domain, G-beta repeat PglZ PF08665.12 EGC37470.1 - 0.011 15.8 1.7 0.067 13.3 1.7 2.4 1 0 0 1 1 1 0 PglZ domain PQQ_3 PF13570.6 EGC37470.1 - 0.21 12.1 0.0 4.2 8.0 0.0 2.8 2 0 0 2 2 2 0 PQQ-like domain AAA PF00004.29 EGC37471.1 - 3.8e-43 147.1 0.0 8.2e-43 146.0 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC37471.1 - 8.1e-10 38.3 0.4 1.7e-09 37.4 0.4 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_16 PF13191.6 EGC37471.1 - 1.3e-07 32.1 0.0 0.00013 22.4 0.0 2.6 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.14 EGC37471.1 - 1.8e-07 31.3 0.2 2.9e-06 27.3 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGC37471.1 - 1.9e-06 27.7 0.0 5.1e-06 26.3 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_2 PF07724.14 EGC37471.1 - 2e-05 24.8 0.0 4.8e-05 23.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) Prot_ATP_ID_OB PF16450.5 EGC37471.1 - 4.6e-05 23.3 0.0 0.0001 22.2 0.0 1.6 1 0 0 1 1 1 1 Proteasomal ATPase OB C-terminal domain AAA_22 PF13401.6 EGC37471.1 - 5.7e-05 23.4 0.1 0.007 16.6 0.0 2.6 1 1 1 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGC37471.1 - 0.00036 20.9 0.0 0.0024 18.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase AAA_18 PF13238.6 EGC37471.1 - 0.0006 20.4 0.1 0.0032 18.0 0.0 2.2 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGC37471.1 - 0.0015 18.1 0.0 0.0031 17.0 0.0 1.6 1 1 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGC37471.1 - 0.0019 17.5 0.0 0.0041 16.4 0.0 1.5 1 0 0 1 1 1 1 TIP49 P-loop domain TsaE PF02367.17 EGC37471.1 - 0.0026 17.8 0.0 0.0051 16.8 0.0 1.4 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF815 PF05673.13 EGC37471.1 - 0.0026 17.0 0.0 0.0046 16.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.17 EGC37471.1 - 0.0027 17.5 0.0 0.0057 16.4 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.6 EGC37471.1 - 0.0033 17.5 0.1 0.0088 16.1 0.0 1.7 2 0 0 2 2 1 1 AAA domain Mg_chelatase PF01078.21 EGC37471.1 - 0.0034 16.8 0.0 0.0069 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.6 EGC37471.1 - 0.0056 16.8 0.0 0.01 16.0 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.26 EGC37471.1 - 0.0063 16.2 0.0 0.025 14.3 0.0 2.0 1 1 1 2 2 2 1 Sigma-54 interaction domain ATPase_2 PF01637.18 EGC37471.1 - 0.01 15.8 0.3 0.063 13.2 0.0 2.2 2 1 0 2 2 2 0 ATPase domain predominantly from Archaea Parvo_NS1 PF01057.17 EGC37471.1 - 0.013 14.6 0.0 0.028 13.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.11 EGC37471.1 - 0.016 15.0 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.12 EGC37471.1 - 0.017 15.0 0.0 0.048 13.6 0.0 1.8 2 0 0 2 2 2 0 NACHT domain AAA_24 PF13479.6 EGC37471.1 - 0.024 14.4 0.0 0.049 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC37471.1 - 0.035 13.8 0.0 0.065 12.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGC37471.1 - 0.039 14.0 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit ATPase PF06745.13 EGC37471.1 - 0.039 13.3 0.1 0.15 11.4 0.0 2.0 3 0 0 3 3 3 0 KaiC AAA_28 PF13521.6 EGC37471.1 - 0.053 13.8 0.0 0.093 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.6 EGC37471.1 - 0.054 13.3 1.6 0.29 10.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.27 EGC37471.1 - 0.065 13.8 0.0 0.16 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter PhoH PF02562.16 EGC37471.1 - 0.066 12.7 0.0 0.13 11.7 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_19 PF13245.6 EGC37471.1 - 0.094 13.1 0.0 0.23 11.8 0.0 1.7 2 0 0 2 2 1 0 AAA domain Zeta_toxin PF06414.12 EGC37471.1 - 0.14 11.4 1.0 0.43 9.8 0.1 2.1 2 0 0 2 2 2 0 Zeta toxin AAA_25 PF13481.6 EGC37471.1 - 0.17 11.4 0.0 0.43 10.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Transferase PF02458.15 EGC37472.1 - 2.4e-09 36.4 0.0 3.5e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Transferase family Transferase PF02458.15 EGC37473.1 - 1.4e-05 23.9 0.0 0.00013 20.8 0.0 2.0 1 1 0 1 1 1 1 Transferase family Phospholip_A2_2 PF05826.12 EGC37473.1 - 0.17 12.1 0.5 3.7 7.8 0.0 2.9 3 0 0 3 3 3 0 Phospholipase A2 PTCRA PF15028.6 EGC37473.1 - 0.2 11.4 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Pre-T-cell antigen receptor DAGK_cat PF00781.24 EGC37474.1 - 1.1e-26 92.9 0.0 2.1e-26 92.0 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain FeS_assembly_P PF01883.19 EGC37475.1 - 4.6e-14 52.3 0.0 6e-14 52.0 0.0 1.2 1 0 0 1 1 1 1 Iron-sulfur cluster assembly protein S4 PF01479.25 EGC37476.1 - 8.3e-11 41.4 0.8 3.3e-10 39.5 0.8 2.1 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.19 EGC37476.1 - 6.1e-05 23.8 0.2 0.00018 22.3 0.0 2.0 1 1 1 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain Thioredoxin PF00085.20 EGC37477.1 - 2.8e-31 107.6 0.0 3.9e-14 52.5 0.0 3.8 3 0 0 3 3 3 2 Thioredoxin Thioredoxin_6 PF13848.6 EGC37477.1 - 1.7e-16 60.7 10.0 6e-16 58.9 3.9 3.3 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_2 PF13098.6 EGC37477.1 - 3.9e-05 24.1 3.7 0.38 11.2 0.0 5.3 4 1 1 5 5 5 2 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGC37477.1 - 0.0008 19.5 0.0 2.6 8.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like OAD_gamma PF04277.13 EGC37477.1 - 1.4 9.6 0.0 1.4 9.6 0.0 3.5 4 0 0 4 4 4 0 Oxaloacetate decarboxylase, gamma chain DUF167 PF02594.16 EGC37478.1 - 4.3e-23 81.2 0.3 5.4e-23 80.9 0.3 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 eRF1_3 PF03465.15 EGC37479.1 - 0.043 14.3 0.1 0.67 10.5 0.1 2.4 1 1 1 2 2 2 0 eRF1 domain 3 APG6_N PF17675.1 EGC37479.1 - 0.31 11.6 3.4 0.21 12.1 1.7 1.6 2 0 0 2 2 2 0 Apg6 coiled-coil region DUF3439 PF11921.8 EGC37479.1 - 1.1 9.3 11.4 2.2 8.3 10.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) GRAM PF02893.20 EGC37480.1 - 1.9e-25 89.0 4.9 2.8e-16 59.4 0.2 3.4 3 0 0 3 3 3 2 GRAM domain C2 PF00168.30 EGC37480.1 - 1.4e-18 67.1 0.4 5.5e-12 45.9 0.0 2.9 2 0 0 2 2 2 2 C2 domain Membr_traf_MHD PF10540.9 EGC37480.1 - 0.0023 18.1 2.1 0.11 12.7 0.1 3.9 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain ubiquitin PF00240.23 EGC37480.1 - 0.051 13.3 0.2 0.36 10.6 0.0 2.7 2 0 0 2 2 2 0 Ubiquitin family Nramp PF01566.18 EGC37481.1 - 3.9e-132 440.6 24.0 5.5e-132 440.1 24.0 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Coiled PF05710.12 EGC37483.1 - 2.3 9.1 16.0 15 6.5 16.0 1.9 1 1 0 1 1 1 0 Coiled coil ATP-synt_C PF00137.21 EGC37484.1 - 1.3e-28 99.1 31.8 7.2e-15 55.1 10.3 2.2 2 0 0 2 2 2 2 ATP synthase subunit C SLATT_5 PF18160.1 EGC37484.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 SMODS and SLOG-associating 2TM effector domain family 5 Cyt_c_ox_IV PF12270.8 EGC37484.1 - 7 6.8 12.6 5.1 7.2 4.7 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV RhoGAP PF00620.27 EGC37485.1 - 1.8e-35 122.0 0.4 1.8e-35 122.0 0.4 2.0 2 0 0 2 2 2 1 RhoGAP domain F-box-like PF12937.7 EGC37485.1 - 2.4e-11 43.4 1.2 5.4e-11 42.2 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC37485.1 - 2.8e-08 33.4 0.4 8.1e-08 32.0 0.4 1.9 1 0 0 1 1 1 1 F-box domain PH PF00169.29 EGC37485.1 - 1.6e-06 28.6 9.2 0.0086 16.6 1.0 4.0 2 1 1 3 3 3 3 PH domain Mcp5_PH PF12814.7 EGC37485.1 - 0.00053 20.1 1.1 0.0018 18.4 1.1 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.6 EGC37485.1 - 0.13 12.7 0.2 0.13 12.7 0.2 3.4 3 1 0 3 3 3 0 Pleckstrin homology domain DnaJ PF00226.31 EGC37486.1 - 4.3e-11 42.8 1.3 4.3e-11 42.8 1.3 1.7 2 0 0 2 2 2 1 DnaJ domain UCH_N PF16674.5 EGC37486.1 - 0.068 13.1 0.2 0.13 12.2 0.2 1.4 1 0 0 1 1 1 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 OTU PF02338.19 EGC37487.1 - 2.4e-12 47.4 0.0 2.4e-12 47.4 0.0 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease Ndc1_Nup PF09531.10 EGC37487.1 - 0.015 14.0 9.6 0.015 14.0 9.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NYN_YacP PF05991.11 EGC37487.1 - 1 9.2 4.5 1.9 8.4 4.5 1.4 1 0 0 1 1 1 0 YacP-like NYN domain DUF2981 PF11200.8 EGC37487.1 - 1.8 8.3 7.1 2.5 7.8 7.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) PTS_EIIB PF00367.20 EGC37488.1 - 2.5 7.6 4.6 19 4.9 0.0 3.5 3 1 1 4 4 4 0 phosphotransferase system, EIIB Neur_chan_memb PF02932.16 EGC37489.1 - 3.5 7.6 5.8 4 7.4 5.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FecR PF04773.13 EGC37490.1 - 1.1 9.9 4.5 2.3 8.9 0.1 3.8 4 0 0 4 4 4 0 FecR protein zf-C2H2_jaz PF12171.8 EGC37491.1 - 3.6e-09 36.7 2.2 6.9e-09 35.8 2.2 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGC37491.1 - 4.4e-07 30.1 1.9 7.6e-07 29.3 1.9 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.12 EGC37491.1 - 0.0034 17.5 1.0 0.0081 16.2 1.0 1.6 1 0 0 1 1 1 1 DBF zinc finger zf_C2H2_ZHX PF18387.1 EGC37491.1 - 0.15 11.7 0.5 0.29 10.8 0.5 1.6 1 1 0 1 1 1 0 Zinc-fingers and homeoboxes C2H2 finger domain zf-C2H2_2 PF12756.7 EGC37491.1 - 0.58 10.5 5.8 0.16 12.3 1.0 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) FOXP-CC PF16159.5 EGC37491.1 - 1.1 9.9 5.6 0.25 12.0 2.2 1.7 2 0 0 2 2 2 0 FOXP coiled-coil domain Y_phosphatase2 PF03162.13 EGC37492.1 - 1.8e-42 144.7 0.0 2e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.27 EGC37492.1 - 0.002 17.7 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.6 EGC37492.1 - 0.043 13.8 0.0 0.054 13.4 0.0 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family DUF2185 PF09951.9 EGC37493.1 - 3.3e-31 107.0 0.1 7.7e-31 105.8 0.1 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF2314 PF10077.9 EGC37493.1 - 0.0034 17.5 0.2 0.26 11.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2314) DUF4443 PF14544.6 EGC37493.1 - 0.1 12.8 0.0 18 5.6 0.0 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4443) TIP49 PF06068.13 EGC37494.1 - 2.4e-155 517.1 3.5 3.3e-155 516.6 3.5 1.2 1 0 0 1 1 1 1 TIP49 P-loop domain TIP49_C PF17856.1 EGC37494.1 - 3.6e-27 94.3 1.5 1.1e-26 92.7 0.6 2.4 3 0 0 3 3 2 1 TIP49 AAA-lid domain AAA PF00004.29 EGC37494.1 - 4e-10 40.2 1.5 1.2e-05 25.8 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGC37494.1 - 5.7e-08 32.7 0.7 0.00077 19.2 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain DnaB_C PF03796.15 EGC37494.1 - 2.7e-06 26.9 0.1 4.9e-06 26.1 0.1 1.5 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_19 PF13245.6 EGC37494.1 - 5e-06 26.9 0.7 5.1e-05 23.6 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC37494.1 - 6.2e-06 26.7 0.2 3.4e-05 24.3 0.2 2.0 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.14 EGC37494.1 - 9.6e-06 25.6 0.2 0.017 15.1 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGC37494.1 - 1.6e-05 25.2 0.1 0.052 13.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGC37494.1 - 3.5e-05 23.6 0.2 0.034 13.9 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGC37494.1 - 0.00039 19.9 0.7 0.02 14.3 0.3 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGC37494.1 - 0.0025 17.7 0.0 0.0051 16.8 0.0 1.5 1 0 0 1 1 1 1 NACHT domain ATPase PF06745.13 EGC37494.1 - 0.0045 16.4 0.4 0.0086 15.5 0.4 1.5 1 0 0 1 1 1 1 KaiC PIF1 PF05970.14 EGC37494.1 - 0.01 15.1 1.4 1.3 8.1 0.4 2.2 2 0 0 2 2 2 0 PIF1-like helicase Zeta_toxin PF06414.12 EGC37494.1 - 0.01 15.1 0.4 0.024 13.9 0.4 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.6 EGC37494.1 - 0.012 16.0 0.9 0.12 12.8 0.3 2.7 2 1 0 2 2 2 0 AAA domain DUF2075 PF09848.9 EGC37494.1 - 0.017 14.4 0.1 0.03 13.6 0.1 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) AAA_25 PF13481.6 EGC37494.1 - 0.017 14.7 0.1 0.043 13.4 0.1 1.6 2 0 0 2 2 2 0 AAA domain ResIII PF04851.15 EGC37494.1 - 0.032 14.2 1.6 1.3 9.0 1.6 2.4 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_7 PF12775.7 EGC37494.1 - 0.039 13.5 0.8 0.15 11.6 0.0 2.3 3 0 0 3 3 3 0 P-loop containing dynein motor region TsaE PF02367.17 EGC37494.1 - 0.076 13.0 0.8 0.27 11.2 0.2 2.2 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_30 PF13604.6 EGC37494.1 - 0.11 12.1 1.1 1.9 8.2 0.3 2.3 2 0 0 2 2 2 0 AAA domain PhoH PF02562.16 EGC37494.1 - 0.2 11.1 2.2 0.88 9.0 0.6 2.3 2 0 0 2 2 2 0 PhoH-like protein NUC173 PF08161.12 EGC37496.1 - 3.6e-60 203.1 1.1 5.8e-59 199.2 0.0 3.2 3 0 0 3 3 3 1 NUC173 domain Phage_int_SAM_4 PF13495.6 EGC37496.1 - 6.6 7.3 6.5 38 4.8 0.0 4.7 5 0 0 5 5 5 0 Phage integrase, N-terminal SAM-like domain zf-LITAF-like PF10601.9 EGC37497.1 - 4.2e-20 71.8 14.9 5.2e-20 71.5 14.9 1.1 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Cytochrome_C7 PF14522.6 EGC37497.1 - 0.0098 15.9 1.4 3.3 7.8 0.4 2.2 2 0 0 2 2 2 2 Cytochrome c7 and related cytochrome c P53_TAD PF08563.11 EGC37497.1 - 1.2 8.7 3.6 1.9 8.1 3.6 1.3 1 0 0 1 1 1 0 P53 transactivation motif Ribosomal_L36 PF00444.18 EGC37498.1 - 5.7e-14 52.0 7.5 7.6e-14 51.6 7.5 1.2 1 0 0 1 1 1 1 Ribosomal protein L36 FBP_C PF16571.5 EGC37498.1 - 0.004 16.7 0.3 0.004 16.7 0.3 1.0 1 0 0 1 1 1 1 FBP C-terminal treble-clef zinc-finger Flu_PA PF00603.17 EGC37498.1 - 0.029 12.5 0.5 0.028 12.6 0.5 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA FAD_binding_4 PF01565.23 EGC37500.1 - 1.1e-20 73.7 0.0 1.8e-20 73.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC37500.1 - 2.2e-07 30.9 1.6 5.9e-07 29.5 1.6 1.8 1 0 0 1 1 1 1 Berberine and berberine like PPR_2 PF13041.6 EGC37502.1 - 0.0017 18.5 0.6 0.0017 18.5 0.6 5.5 6 1 1 7 7 7 2 PPR repeat family PPR PF01535.20 EGC37502.1 - 0.014 15.6 8.9 0.098 13.0 0.0 6.3 9 0 0 9 9 9 0 PPR repeat DUF3439 PF11921.8 EGC37503.1 - 0.094 12.7 22.4 0.14 12.2 4.8 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) FA_hydroxylase PF04116.13 EGC37505.1 - 6.8e-22 78.2 14.8 6.8e-22 78.2 14.8 2.7 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily PBP PF01161.20 EGC37506.1 - 3e-12 47.0 0.1 4e-12 46.6 0.1 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein PI3Ka PF00613.20 EGC37507.1 - 4.1e-61 205.6 0.9 9.8e-61 204.4 0.9 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGC37507.1 - 9.6e-56 189.4 0.3 4.2e-54 184.0 0.3 2.8 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGC37507.1 - 1.3e-28 99.6 0.0 7.2e-28 97.2 0.0 2.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGC37507.1 - 4.5e-16 58.9 0.3 2.6e-15 56.5 0.2 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGC37507.1 - 0.0029 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) ATP-synt_C PF00137.21 EGC37508.1 - 1.9e-27 95.4 35.1 7.7e-17 61.4 13.5 2.2 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.21 EGC37509.1 - 1.4e-30 105.4 34.2 1.7e-19 69.9 14.2 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Fic PF02661.18 EGC37511.1 - 1.8e-20 73.6 0.1 7.1e-20 71.7 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family Speriolin_C PF15059.6 EGC37511.1 - 0.096 12.8 3.0 2.2 8.4 0.0 2.7 3 0 0 3 3 3 0 Speriolin C-terminus DUF5601 PF18151.1 EGC37511.1 - 0.52 10.7 3.6 14 6.1 0.3 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF5601) TAL_FSA PF00923.19 EGC37513.1 - 1.7e-91 306.6 0.5 1.9e-91 306.4 0.5 1.0 1 0 0 1 1 1 1 Transaldolase/Fructose-6-phosphate aldolase PIH1 PF08190.12 EGC37514.1 - 2.8e-12 46.4 3.8 7.6e-12 45.0 3.8 1.8 1 0 0 1 1 1 1 PIH1 N-terminal domain PIH1_CS PF18201.1 EGC37514.1 - 6e-07 29.8 0.3 1.7e-06 28.3 0.3 1.8 1 0 0 1 1 1 1 PIH1 CS-like domain Peptidase_M8 PF01457.16 EGC37515.1 - 2.2e-50 171.9 3.7 5e-50 170.7 3.7 1.5 1 0 0 1 1 1 1 Leishmanolysin ETRAMP PF09716.10 EGC37515.1 - 0.0086 16.1 4.4 0.0086 16.1 4.4 4.3 5 0 0 5 5 5 1 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.12 EGC37519.1 - 9.8e-27 92.9 69.4 6.9e-08 32.5 0.6 13.2 8 4 5 13 13 13 9 FNIP Repeat ubiquitin PF00240.23 EGC37520.1 - 8.2e-07 28.7 0.0 8.7e-07 28.6 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGC37520.1 - 0.016 15.6 0.0 0.016 15.6 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Methyltransf_11 PF08241.12 EGC37521.1 - 1.6e-07 31.9 0.0 3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC37521.1 - 3e-06 27.9 0.0 9.8e-06 26.2 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC37521.1 - 3.1e-06 27.1 0.3 4.2e-06 26.6 0.3 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.6 EGC37521.1 - 9.3e-06 25.7 0.1 1.3e-05 25.3 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC37521.1 - 0.00019 22.1 0.1 0.00039 21.1 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.12 EGC37521.1 - 0.0068 16.0 0.4 0.012 15.2 0.4 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW SNO PF01174.19 EGC37521.1 - 0.022 14.6 0.0 0.038 13.8 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family SpoIIE PF07228.12 EGC37523.1 - 1.6e-11 44.5 0.0 2.3e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.21 EGC37523.1 - 5.6e-07 29.5 1.3 0.018 14.7 0.0 2.9 3 1 1 4 4 4 2 Protein phosphatase 2C PP2C_2 PF13672.6 EGC37523.1 - 0.00011 22.0 0.0 0.00011 22.0 0.0 2.3 2 1 0 3 3 3 1 Protein phosphatase 2C Coprogen_oxidas PF01218.18 EGC37524.1 - 1.9e-107 358.4 0.2 2.2e-107 358.2 0.2 1.0 1 0 0 1 1 1 1 Coproporphyrinogen III oxidase DUF577 PF04510.12 EGC37525.1 - 0.056 13.3 0.1 0.056 13.3 0.1 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF577) DUF4349 PF14257.6 EGC37526.1 - 0.0066 15.9 1.0 0.0066 15.9 1.0 2.2 1 1 1 2 2 2 1 Domain of unknown function (DUF4349) CCDC84 PF14968.6 EGC37526.1 - 0.031 13.9 16.3 0.049 13.3 16.3 1.3 1 0 0 1 1 1 0 Coiled coil protein 84 Pox_A_type_inc PF04508.12 EGC37526.1 - 0.034 14.0 2.1 0.33 10.9 1.5 2.9 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat Med15 PF09606.10 EGC37526.1 - 0.16 10.6 36.0 0.29 9.8 36.0 1.4 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TetR_C_24 PF17932.1 EGC37526.1 - 1.6 9.0 8.4 0.19 12.0 1.1 2.4 2 0 0 2 2 2 0 Tetracyclin repressor-like, C-terminal domain DUF4407 PF14362.6 EGC37526.1 - 3 7.1 20.0 5.5 6.2 20.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Peptidase_M16_C PF05193.21 EGC37527.1 - 1.2e-37 129.7 0.0 1.6e-37 129.3 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC37527.1 - 0.0022 18.0 0.0 0.0047 16.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Tmemb_14 PF03647.13 EGC37528.1 - 2.2e-26 92.4 13.0 2.5e-26 92.2 13.0 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.18 EGC37528.1 - 0.17 11.2 10.5 0.19 11.0 10.5 1.0 1 0 0 1 1 1 0 UbiA prenyltransferase family DUF2070 PF09843.9 EGC37528.1 - 7.9 4.6 8.8 8.1 4.6 8.8 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) MJ1316 PF04457.12 EGC37529.1 - 1.1e-12 48.5 1.1 3.7e-12 46.8 1.1 1.9 1 1 0 1 1 1 1 MJ1316 RNA cyclic group end recognition domain vATP-synt_E PF01991.18 EGC37529.1 - 0.013 14.9 4.6 0.021 14.3 4.6 1.3 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit Maelstrom PF13017.6 EGC37529.1 - 0.014 15.1 1.2 0.023 14.4 1.2 1.3 1 0 0 1 1 1 0 piRNA pathway germ-plasm component OSCP PF00213.18 EGC37529.1 - 0.014 15.5 1.0 0.021 15.0 1.0 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF846 PF05832.12 EGC37530.1 - 1.9e-51 173.8 15.3 2.6e-51 173.3 15.3 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) DUF2207 PF09972.9 EGC37530.1 - 4.4 6.0 10.4 0.54 9.0 3.5 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) Mic1 PF07035.12 EGC37531.1 - 3e-52 176.5 2.2 3e-52 176.5 2.2 2.0 2 0 0 2 2 2 1 Colon cancer-associated protein Mic1-like TFIIA PF03153.13 EGC37531.1 - 2.6 8.0 38.4 1 9.2 14.9 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tim54 PF11711.8 EGC37531.1 - 10 4.8 10.9 0.74 8.5 3.1 2.2 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Fz PF01392.22 EGC37532.1 - 9.9e-07 29.4 8.9 2.2e-06 28.3 8.9 1.6 1 0 0 1 1 1 1 Fz domain Ependymin PF00811.18 EGC37532.1 - 0.00011 22.5 1.7 0.00018 21.8 0.3 2.0 2 0 0 2 2 2 1 Ependymin VioE PF18234.1 EGC37532.1 - 0.035 14.2 0.0 0.15 12.1 0.0 1.8 1 1 0 2 2 2 0 Violacein biosynthetic enzyme VioE DRY_EERY PF09750.9 EGC37532.1 - 0.039 14.2 0.0 0.13 12.5 0.0 1.7 2 0 0 2 2 2 0 Alternative splicing regulator MIF4G PF02854.19 EGC37533.1 - 2e-30 106.0 6.7 2.3e-30 105.8 6.7 1.1 1 0 0 1 1 1 1 MIF4G domain TPR_2 PF07719.17 EGC37534.1 - 8.9e-08 31.7 1.4 0.14 12.4 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37534.1 - 3.2e-07 30.1 4.2 0.0055 16.8 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC37534.1 - 4.1e-06 26.8 0.3 0.2 12.1 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37534.1 - 8.4e-05 22.2 3.6 0.28 11.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC37534.1 - 0.0012 19.4 0.1 0.35 11.4 0.0 3.2 3 1 0 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.12 EGC37534.1 - 0.024 14.4 1.4 33 4.2 0.0 3.1 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 TPR_11 PF13414.6 EGC37534.1 - 0.057 13.1 0.2 2.5 7.9 0.0 3.2 4 1 1 5 5 5 0 TPR repeat Fis1_TPR_C PF14853.6 EGC37534.1 - 0.082 13.0 0.1 34 4.6 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.6 EGC37534.1 - 0.2 11.8 1.7 2.4 8.4 0.0 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat Abhydrolase_1 PF00561.20 EGC37535.1 - 4e-09 36.5 0.0 1.1e-08 35.0 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC37535.1 - 0.00044 19.6 0.0 0.0006 19.2 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Ndr PF03096.14 EGC37535.1 - 0.023 13.4 0.4 0.042 12.5 0.0 1.5 2 0 0 2 2 2 0 Ndr family FSH1 PF03959.13 EGC37535.1 - 0.026 14.2 0.0 0.11 12.1 0.0 2.1 2 1 0 2 2 2 0 Serine hydrolase (FSH1) DUF1464 PF07318.12 EGC37535.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) zf-ANAPC11 PF12861.7 EGC37536.1 - 1.8e-31 108.0 17.6 2e-31 107.9 17.6 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.7 EGC37536.1 - 7.5e-22 77.4 18.6 9.7e-22 77.0 18.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC37536.1 - 8.6e-06 26.0 21.4 0.00013 22.2 21.2 2.2 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37536.1 - 0.00059 19.6 10.9 0.00059 19.6 10.9 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37536.1 - 0.019 14.8 19.5 0.028 14.3 17.3 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.8 EGC37536.1 - 0.052 13.4 8.6 0.11 12.3 8.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF5318 PF17249.2 EGC37536.1 - 0.27 11.0 3.0 2.1 8.1 0.2 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF5318) Zn_ribbon_17 PF17120.5 EGC37536.1 - 8.5 6.1 24.7 19 5.0 21.3 2.6 1 1 1 2 2 2 0 Zinc-ribbon, C4HC2 type GBP PF02263.19 EGC37537.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Guanylate-binding protein, N-terminal domain ABC2_membrane PF01061.24 EGC37539.1 - 1.2e-37 129.4 16.7 1.2e-37 129.4 16.7 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC37539.1 - 1.9e-25 90.0 0.0 3.2e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC37539.1 - 3.1e-05 23.9 0.2 0.09 12.6 0.2 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGC37539.1 - 5.4e-05 22.5 17.8 5.4e-05 22.5 17.8 2.0 2 1 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGC37539.1 - 6.1e-05 23.0 0.6 0.00012 22.0 0.6 1.4 1 0 0 1 1 1 1 RsgA GTPase AAA_25 PF13481.6 EGC37539.1 - 0.0001 22.0 0.0 0.00017 21.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.6 EGC37539.1 - 0.00012 21.7 0.1 0.00027 20.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC37539.1 - 0.00068 20.1 0.0 0.0011 19.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC37539.1 - 0.0047 17.2 0.0 0.042 14.1 0.0 2.5 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGC37539.1 - 0.014 16.0 0.0 0.032 14.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain SMC_N PF02463.19 EGC37539.1 - 0.018 14.4 0.1 0.41 10.0 0.0 2.5 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Rad17 PF03215.15 EGC37539.1 - 0.061 13.2 0.1 0.16 11.8 0.1 1.8 2 0 0 2 2 1 0 Rad17 P-loop domain AAA_28 PF13521.6 EGC37539.1 - 0.1 12.8 0.3 0.18 12.0 0.3 1.3 1 0 0 1 1 1 0 AAA domain Cytidylate_kin PF02224.18 EGC37539.1 - 0.11 12.2 0.0 0.21 11.3 0.0 1.5 1 0 0 1 1 1 0 Cytidylate kinase PDR_CDR PF06422.12 EGC37539.1 - 0.12 12.3 0.2 0.12 12.3 0.2 2.5 2 0 0 2 2 1 0 CDR ABC transporter AAA_33 PF13671.6 EGC37539.1 - 0.13 12.5 0.1 0.26 11.4 0.1 1.5 1 0 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC37539.1 - 0.19 11.4 0.0 0.35 10.6 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein NACHT PF05729.12 EGC37539.1 - 0.2 11.6 0.2 0.43 10.5 0.2 1.6 1 0 0 1 1 1 0 NACHT domain AAA_30 PF13604.6 EGC37539.1 - 0.21 11.3 0.0 0.34 10.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC37539.1 - 0.59 10.6 0.0 0.59 10.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain Mhr1 PF12829.7 EGC37540.1 - 0.0091 16.1 0.3 0.018 15.1 0.3 1.5 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RAI1 PF08652.11 EGC37540.1 - 0.56 10.4 5.9 0.34 11.1 1.0 2.2 1 1 1 2 2 2 0 RAI1 like PD-(D/E)XK nuclease EGF_Tenascin PF18720.1 EGC37541.1 - 0.0013 18.7 1.5 0.0018 18.3 1.5 1.3 1 0 0 1 1 1 1 Tenascin EGF domain EGF_alliinase PF04863.13 EGC37541.1 - 0.0075 16.6 1.6 0.012 16.0 1.6 1.4 1 0 0 1 1 1 1 Alliinase EGF-like domain EGF_2 PF07974.13 EGC37541.1 - 0.069 13.5 2.7 0.069 13.5 2.7 1.7 2 0 0 2 2 2 0 EGF-like domain Golgin_A5 PF09787.9 EGC37542.1 - 0.41 10.1 26.1 0.76 9.2 26.1 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Jnk-SapK_ap_N PF09744.9 EGC37542.1 - 1.4 9.1 36.6 0.038 14.2 14.5 3.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 DUF2381 PF09544.10 EGC37542.1 - 2.5 7.5 4.3 1.2 8.7 1.2 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2381) DUF4834 PF16118.5 EGC37543.1 - 2.3e-05 25.3 3.4 3e-05 24.9 3.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF2681 PF10883.8 EGC37543.1 - 0.00057 20.2 6.1 0.00071 19.9 6.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) CRA PF06589.11 EGC37543.1 - 0.0011 19.0 0.1 0.0013 18.8 0.1 1.1 1 0 0 1 1 1 1 Circumsporozoite-related antigen (CRA) Serinc PF03348.15 EGC37543.1 - 0.0029 16.6 1.3 0.0031 16.5 1.3 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) MMM1 PF10296.9 EGC37543.1 - 0.0042 16.2 1.8 0.0045 16.1 1.8 1.0 1 0 0 1 1 1 1 Maintenance of mitochondrial morphology protein 1 DUF5327 PF17261.2 EGC37543.1 - 0.0052 17.5 9.1 0.0061 17.3 9.1 1.1 1 0 0 1 1 1 1 Family of unknown function (DUF5327) SID-1_RNA_chan PF13965.6 EGC37543.1 - 0.0068 14.9 2.3 0.0069 14.9 2.3 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 FAM176 PF14851.6 EGC37543.1 - 0.0074 15.9 0.6 0.0083 15.8 0.6 1.0 1 0 0 1 1 1 1 FAM176 family Mucin PF01456.17 EGC37543.1 - 0.0081 16.2 2.6 0.0092 16.0 2.6 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein OSTbeta PF15048.6 EGC37543.1 - 0.0082 16.3 0.1 0.0087 16.2 0.1 1.1 1 0 0 1 1 1 1 Organic solute transporter subunit beta protein WBP-1 PF11669.8 EGC37543.1 - 0.012 16.2 0.5 0.016 15.8 0.5 1.3 1 0 0 1 1 1 0 WW domain-binding protein 1 Ctr PF04145.15 EGC37543.1 - 0.015 15.9 0.6 0.018 15.6 0.6 1.1 1 0 0 1 1 1 0 Ctr copper transporter family DUF2149 PF09919.9 EGC37543.1 - 0.021 15.1 0.8 0.024 14.9 0.8 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Ureide_permease PF07168.11 EGC37543.1 - 0.021 13.6 0.6 0.024 13.4 0.6 1.0 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 EGC37543.1 - 0.024 14.4 2.4 0.025 14.4 2.4 1.0 1 0 0 1 1 1 0 Connexin CLN3 PF02487.17 EGC37543.1 - 0.026 13.6 3.8 0.027 13.5 3.8 1.0 1 0 0 1 1 1 0 CLN3 protein AIF_C PF14721.6 EGC37543.1 - 0.027 14.8 1.4 0.029 14.7 1.4 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term FAM209 PF15206.6 EGC37543.1 - 0.027 14.3 0.3 0.031 14.1 0.3 1.1 1 0 0 1 1 1 0 FAM209 family V_ATPase_I PF01496.19 EGC37543.1 - 0.03 12.3 3.7 0.033 12.1 3.7 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Zip PF02535.22 EGC37543.1 - 0.038 13.2 2.5 0.045 13.0 2.5 1.0 1 0 0 1 1 1 0 ZIP Zinc transporter FHIPEP PF00771.20 EGC37543.1 - 0.041 12.4 1.0 0.042 12.3 1.0 1.0 1 0 0 1 1 1 0 FHIPEP family UPF0239 PF06783.11 EGC37543.1 - 0.042 14.0 0.7 0.052 13.7 0.7 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0239) PRC2_HTH_1 PF18118.1 EGC37543.1 - 0.045 14.5 3.5 0.053 14.3 3.5 1.1 1 0 0 1 1 1 0 Polycomb repressive complex 2 tri-helical domain Kei1 PF08552.11 EGC37543.1 - 0.048 13.5 2.0 0.059 13.2 2.0 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Cadherin_C_2 PF16492.5 EGC37543.1 - 0.048 14.4 1.2 0.058 14.2 1.2 1.1 1 0 0 1 1 1 0 Cadherin cytoplasmic C-terminal Nucleoside_tran PF01733.18 EGC37543.1 - 0.092 12.1 0.2 0.1 12.0 0.2 1.0 1 0 0 1 1 1 0 Nucleoside transporter Spt20 PF12090.8 EGC37543.1 - 0.11 12.1 28.8 0.12 11.9 28.8 1.0 1 0 0 1 1 1 0 Spt20 family GRP PF07172.11 EGC37543.1 - 0.12 13.1 0.0 0.16 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family DUF2547 PF10818.8 EGC37543.1 - 0.13 13.2 12.0 0.16 12.9 12.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Gti1_Pac2 PF09729.9 EGC37543.1 - 0.14 12.2 5.8 0.15 12.1 5.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family OATP PF03137.20 EGC37543.1 - 0.15 10.3 1.8 0.15 10.3 1.8 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family O-antigen_lig PF13425.6 EGC37543.1 - 0.15 10.8 0.9 0.15 10.8 0.9 1.0 1 0 0 1 1 1 0 O-antigen ligase like membrane protein DUF4064 PF13273.6 EGC37543.1 - 0.17 12.2 4.1 0.29 11.5 4.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DcuA_DcuB PF03605.14 EGC37543.1 - 0.19 10.6 0.9 0.22 10.4 0.9 1.1 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter EOS1 PF12326.8 EGC37543.1 - 0.19 11.6 1.9 0.2 11.5 1.9 1.1 1 0 0 1 1 1 0 N-glycosylation protein DUF4199 PF13858.6 EGC37543.1 - 0.21 12.0 1.6 0.22 11.9 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) ABC2_membrane_2 PF12679.7 EGC37543.1 - 0.24 10.7 0.6 0.25 10.6 0.6 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein CSG2 PF16965.5 EGC37543.1 - 0.27 10.1 1.9 0.28 10.1 1.9 1.0 1 0 0 1 1 1 0 Ceramide synthase regulator HCO3_cotransp PF00955.21 EGC37543.1 - 0.28 9.9 2.8 0.3 9.9 2.8 1.0 1 0 0 1 1 1 0 HCO3- transporter family SelP_N PF04592.14 EGC37543.1 - 0.29 10.5 11.4 0.34 10.3 11.4 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Coilin_N PF15862.5 EGC37543.1 - 0.41 10.4 7.5 0.5 10.2 7.5 1.1 1 0 0 1 1 1 0 Coilin N-terminus PigN PF04987.14 EGC37543.1 - 0.42 9.4 2.2 0.47 9.3 2.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositolglycan class N (PIG-N) TERB2 PF15101.6 EGC37543.1 - 0.42 10.6 12.8 0.48 10.4 12.8 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CPSF100_C PF13299.6 EGC37543.1 - 0.53 10.4 7.1 0.61 10.3 7.1 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal EIIBC-GUT_N PF03612.14 EGC37543.1 - 0.63 9.8 5.1 0.69 9.6 5.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2232 PF09991.9 EGC37543.1 - 0.7 9.0 2.1 0.74 8.9 2.1 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DivIC PF04977.15 EGC37543.1 - 0.76 9.6 7.9 1.1 9.1 7.9 1.3 1 0 0 1 1 1 0 Septum formation initiator EPL1 PF10513.9 EGC37543.1 - 0.96 9.8 12.3 1.1 9.6 12.3 1.0 1 0 0 1 1 1 0 Enhancer of polycomb-like EphA2_TM PF14575.6 EGC37543.1 - 1.1 10.2 7.9 5.8 7.9 7.9 1.9 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain DUF3573 PF12097.8 EGC37543.1 - 1.2 7.9 7.1 1.2 7.9 7.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) Band_3_cyto PF07565.13 EGC37543.1 - 1.2 8.8 7.6 1.4 8.7 7.6 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF2722 PF10846.8 EGC37543.1 - 1.7 7.5 24.6 2 7.2 24.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) Suf PF05843.14 EGC37543.1 - 2.4 8.0 10.9 2.6 7.9 10.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) ALMT PF11744.8 EGC37543.1 - 2.6 6.8 6.1 2.7 6.7 6.1 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter CobT PF06213.12 EGC37543.1 - 3.6 6.9 12.0 4.1 6.7 12.0 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Ank_2 PF12796.7 EGC37544.1 - 0.00049 20.6 0.1 0.031 14.9 0.0 3.1 2 1 1 3 3 3 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC37544.1 - 0.0036 17.8 0.6 1.2 9.8 0.1 4.1 3 2 0 3 3 3 1 Ankyrin repeats (many copies) Activator_LAG-3 PF11498.8 EGC37544.1 - 0.78 8.6 10.8 1.2 8.0 10.8 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ferrochelatase PF00762.19 EGC37545.1 - 3.4e-109 364.8 0.0 4.1e-109 364.5 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase KfrA_N PF11740.8 EGC37545.1 - 0.094 13.4 0.0 0.27 11.9 0.0 1.8 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Metallophos_2 PF12850.7 EGC37546.1 - 1.2e-24 87.3 0.2 1.5e-24 87.1 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.28 EGC37546.1 - 0.0021 18.6 0.7 0.79 10.2 0.3 2.3 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Xan_ur_permease PF00860.20 EGC37547.1 - 1.2e-77 261.2 40.8 1.8e-77 260.7 40.8 1.1 1 0 0 1 1 1 1 Permease family CAP_N PF01213.19 EGC37548.1 - 8.2e-101 337.6 4.6 1.1e-100 337.3 4.6 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.11 EGC37548.1 - 5.1e-63 211.4 9.1 8.5e-63 210.7 9.1 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.12 EGC37548.1 - 0.0021 17.8 4.3 0.0043 16.8 4.3 1.5 1 0 0 1 1 1 1 Tubulin binding cofactor C Goodbye PF17109.5 EGC37548.1 - 0.0057 17.1 0.5 0.041 14.3 0.3 2.4 2 0 0 2 2 2 1 fungal STAND N-terminal Goodbye domain DUF4523 PF15023.6 EGC37548.1 - 0.05 13.4 0.3 0.16 11.8 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4523) DUF2408 PF10303.9 EGC37548.1 - 0.12 12.9 1.1 0.62 10.6 1.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2408) MCRS_N PF13325.6 EGC37548.1 - 0.17 11.9 0.8 0.61 10.1 0.6 1.9 1 1 1 2 2 2 0 N-terminal region of micro-spherule protein Ribosomal_60s PF00428.19 EGC37548.1 - 0.62 10.7 15.9 0.24 12.0 0.7 3.1 3 1 0 3 3 3 0 60s Acidic ribosomal protein DUF2418 PF10332.9 EGC37549.1 - 1.3e-16 60.9 2.1 2e-16 60.3 0.6 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) Colicin_V PF02674.16 EGC37549.1 - 0.34 10.9 7.1 1.4 8.9 7.1 1.8 1 1 0 1 1 1 0 Colicin V production protein GST_C_3 PF14497.6 EGC37550.1 - 2.3e-14 53.4 1.3 3.5e-14 52.8 0.7 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC37550.1 - 7e-11 42.3 0.0 5.7e-10 39.4 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC37550.1 - 5e-09 36.4 0.0 1.5e-08 34.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC37550.1 - 5.6e-09 36.1 0.4 1.6e-08 34.6 0.4 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC37550.1 - 0.0053 16.8 0.0 0.01 15.8 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_4 PF17172.4 EGC37550.1 - 0.013 16.2 0.0 0.039 14.7 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase N-terminal domain GST_N_2 PF13409.6 EGC37550.1 - 0.031 14.6 0.0 0.072 13.4 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain FNIP PF05725.12 EGC37551.1 - 2.5e-188 610.1 65.2 6.2e-17 61.5 0.0 14.1 3 3 12 18 18 18 18 FNIP Repeat LRR_5 PF13306.6 EGC37551.1 - 4.6e-08 33.1 2.7 0.004 17.1 0.0 4.3 2 2 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC37551.1 - 8.2e-05 22.7 15.5 27 5.1 0.1 11.4 10 3 4 14 14 14 1 Protein of unknown function (DUF1769) Phage_min_tail PF05939.13 EGC37551.1 - 0.015 15.7 0.1 27 5.2 0.0 4.7 5 0 0 5 5 5 0 Phage minor tail protein DUF4998 PF16389.5 EGC37551.1 - 0.1 12.2 0.0 3.6 7.1 0.0 3.1 4 0 0 4 4 4 0 Domain of unknown function COG7 PF10191.9 EGC37553.1 - 3.6e-102 343.0 45.6 1.7e-85 287.8 31.0 3.1 3 0 0 3 3 3 3 Golgi complex component 7 (COG7) DUF4860 PF16152.5 EGC37553.1 - 0.017 15.0 0.6 0.048 13.5 0.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4860) Fz PF01392.22 EGC37554.1 - 1.5e-05 25.6 8.2 3.5e-05 24.4 8.2 1.6 1 0 0 1 1 1 1 Fz domain Ependymin PF00811.18 EGC37554.1 - 0.001 19.3 0.4 0.001 19.3 0.4 2.0 2 1 1 3 3 3 1 Ependymin VioE PF18234.1 EGC37554.1 - 0.034 14.3 0.0 0.44 10.7 0.0 2.1 2 0 0 2 2 2 0 Violacein biosynthetic enzyme VioE PAGK PF15284.6 EGC37554.1 - 0.088 12.7 0.4 0.2 11.6 0.4 1.6 1 0 0 1 1 1 0 Phage-encoded virulence factor Rit1_C PF17184.4 EGC37555.1 - 1.7e-90 303.2 0.1 2.4e-90 302.7 0.1 1.2 1 0 0 1 1 1 1 Rit1 N-terminal domain Init_tRNA_PT PF04179.12 EGC37555.1 - 2.4e-21 76.1 0.2 5.7e-21 74.9 0.2 1.6 1 0 0 1 1 1 1 Rit1 DUSP-like domain SwrA PF17423.2 EGC37555.1 - 3 7.9 6.4 3.9 7.5 0.4 2.7 2 0 0 2 2 2 0 Swarming motility protein FNIP PF05725.12 EGC37556.1 - 2.6e-72 238.7 36.0 4.4e-15 55.6 0.9 6.6 6 1 1 7 7 7 6 FNIP Repeat LRR_5 PF13306.6 EGC37556.1 - 0.003 17.5 1.5 0.003 17.5 1.5 2.0 2 1 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) Voltage_CLC PF00654.20 EGC37557.1 - 8.4e-67 225.9 27.8 8.4e-67 225.9 27.8 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.28 EGC37557.1 - 3.7e-08 33.7 0.2 0.00031 21.1 0.1 2.6 2 0 0 2 2 2 2 CBS domain PTRF_SDPR PF15237.6 EGC37557.1 - 0.064 12.9 5.8 0.12 11.9 5.8 1.3 1 0 0 1 1 1 0 PTRF/SDPR family HTH_40 PF14493.6 EGC37559.1 - 0.087 13.3 1.9 0.52 10.8 0.0 2.6 2 0 0 2 2 2 0 Helix-turn-helix domain CLZ PF16526.5 EGC37560.1 - 0.072 13.4 0.6 0.16 12.3 0.1 1.8 2 0 0 2 2 2 0 C-terminal leucine zipper domain of cyclic nucleotide-gated channels Peptidase_S24 PF00717.23 EGC37561.1 - 2.9e-08 33.6 0.2 4.6e-08 32.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like TLD PF07534.16 EGC37562.1 - 4e-37 127.5 1.3 4e-37 127.5 1.3 2.9 3 0 0 3 3 3 1 TLD LysM PF01476.20 EGC37562.1 - 1.3e-06 28.3 0.2 5.4e-06 26.4 0.0 2.2 2 0 0 2 2 2 1 LysM domain WD40 PF00400.32 EGC37562.1 - 0.00064 20.5 7.6 0.064 14.2 0.4 4.6 4 0 0 4 4 4 2 WD domain, G-beta repeat GRAM PF02893.20 EGC37562.1 - 0.013 15.4 0.3 0.052 13.4 0.0 2.2 2 0 0 2 2 2 0 GRAM domain ANAPC4_WD40 PF12894.7 EGC37562.1 - 0.23 11.8 4.4 0.6 10.4 1.3 3.4 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain RWD PF05773.22 EGC37562.1 - 3.6 7.9 11.9 0.13 12.5 1.9 3.2 3 0 0 3 3 3 0 RWD domain Tweety PF04906.13 EGC37563.1 - 0.00065 18.5 8.0 0.041 12.6 1.4 2.5 2 0 0 2 2 2 2 Tweety Wzy_C PF04932.15 EGC37563.1 - 0.0061 16.2 5.1 0.25 10.9 0.0 2.5 1 1 1 2 2 2 1 O-Antigen ligase DUF2207 PF09972.9 EGC37563.1 - 0.026 13.3 0.4 0.026 13.3 0.4 2.3 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) CYYR1 PF10873.8 EGC37563.1 - 0.033 14.6 2.2 0.033 14.6 2.2 3.0 4 0 0 4 4 4 0 Cysteine and tyrosine-rich protein 1 Polysacc_synt PF01943.17 EGC37563.1 - 0.052 12.9 0.4 0.052 12.9 0.4 2.7 3 1 0 3 3 3 0 Polysaccharide biosynthesis protein Flagellin_N PF00669.20 EGC37563.1 - 0.071 13.2 2.7 0.99 9.5 3.6 2.1 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF1664 PF07889.12 EGC37563.1 - 0.1 12.7 0.5 0.28 11.2 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) DUF4131 PF13567.6 EGC37563.1 - 0.13 11.9 8.3 4.8 6.8 3.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF148 PF02520.17 EGC37563.1 - 0.3 11.2 3.4 0.29 11.3 1.3 2.0 2 0 0 2 2 2 0 Domain of unknown function DUF148 Pilin_N PF07790.11 EGC37563.1 - 1.6 9.7 9.5 1.2 10.1 0.1 2.8 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal Phage_holin_3_6 PF07332.11 EGC37563.1 - 6.9 6.7 13.9 4.8 7.3 0.1 3.4 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III DUF4984 PF16372.5 EGC37564.1 - 0.13 12.2 0.2 0.14 12.1 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4984) MBOAT PF03062.19 EGC37565.1 - 5.5e-09 35.8 18.7 5.5e-09 35.8 18.7 1.7 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1365 PF07103.11 EGC37566.1 - 5.7e-68 229.2 0.5 1e-67 228.4 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) YL1_C PF08265.11 EGC37567.1 - 6.6e-06 25.8 3.5 1.4 8.7 0.0 3.7 4 0 0 4 4 4 3 YL1 nuclear protein C-terminal domain OCRE PF17780.1 EGC37567.1 - 0.00064 19.7 0.3 18 5.4 0.0 3.4 3 0 0 3 3 3 2 OCRE domain Baculo_PEP_C PF04513.12 EGC37567.1 - 0.13 12.3 26.7 2 8.4 1.2 5.0 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF2184 PF09950.9 EGC37567.1 - 1 8.7 6.6 89 2.3 0.1 3.9 4 0 0 4 4 4 0 Uncharacterized protein conserved in bacteria (DUF2184) Vps51 PF08700.11 EGC37567.1 - 1.7 8.8 13.2 39 4.4 0.2 4.6 5 0 0 5 5 5 0 Vps51/Vps67 MCPsignal PF00015.21 EGC37567.1 - 8 6.2 33.7 8.5 6.1 2.1 5.1 5 0 0 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nup35_RRM PF05172.13 EGC37568.1 - 6.9e-08 32.4 0.1 2.1e-07 30.8 0.1 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGC37568.1 - 9e-05 22.4 0.0 0.00018 21.5 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif tRNA-synt_2_TM PF16995.5 EGC37568.1 - 0.037 13.7 3.4 0.075 12.7 0.1 2.5 1 1 2 3 3 3 0 Transmembrane region of lysyl-tRNA synthetase H_PPase PF03030.16 EGC37568.1 - 0.042 12.5 1.2 0.054 12.1 1.2 1.1 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase RRM_1 PF00076.22 EGC37568.1 - 0.071 12.9 0.0 0.12 12.2 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RseC_MucC PF04246.12 EGC37568.1 - 6.5 6.7 6.5 0.61 10.0 0.3 2.4 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC EamA PF00892.20 EGC37568.1 - 6.6 6.9 18.2 1.5 9.0 2.8 2.5 2 0 0 2 2 2 0 EamA-like transporter family Thioredoxin PF00085.20 EGC37569.1 - 2e-25 88.7 1.4 8.2e-25 86.8 0.2 2.5 2 0 0 2 2 2 1 Thioredoxin UBX PF00789.20 EGC37569.1 - 5.9e-14 52.0 0.0 1.6e-13 50.7 0.0 1.8 1 0 0 1 1 1 1 UBX domain ZZ PF00569.17 EGC37569.1 - 2e-12 46.7 9.0 3.9e-12 45.8 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA PF00627.31 EGC37569.1 - 1.1e-06 28.5 0.0 2e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain C1_2 PF03107.16 EGC37569.1 - 0.00026 21.3 5.4 0.00054 20.2 5.4 1.5 1 0 0 1 1 1 1 C1 domain Thioredoxin_8 PF13905.6 EGC37569.1 - 0.00042 20.6 0.8 0.00095 19.5 0.0 2.1 2 0 0 2 2 2 1 Thioredoxin-like Redoxin PF08534.10 EGC37569.1 - 0.0017 18.1 2.6 0.0021 17.8 0.1 2.3 2 1 1 3 3 3 1 Redoxin Thioredoxin_2 PF13098.6 EGC37569.1 - 0.0028 18.1 0.3 0.0028 18.1 0.3 2.7 2 2 0 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC37569.1 - 0.0028 17.0 0.4 0.0064 15.9 0.4 1.5 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGC37569.1 - 0.0029 17.5 1.8 0.004 17.1 0.1 2.1 2 0 0 2 2 2 1 AhpC/TSA family Thioredoxin_9 PF14595.6 EGC37569.1 - 0.0058 16.4 0.0 0.0058 16.4 0.0 2.9 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_7 PF13899.6 EGC37569.1 - 0.043 14.0 0.1 0.12 12.6 0.1 1.8 1 0 0 1 1 1 0 Thioredoxin-like Borrelia_P83 PF05262.11 EGC37569.1 - 0.65 8.4 16.4 1.1 7.7 16.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein HMG-CoA_red PF00368.18 EGC37571.1 - 8.3e-152 505.4 4.3 1e-151 505.1 4.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase FSA_C PF10479.9 EGC37572.1 - 0.027 12.6 4.8 0.04 12.1 4.8 1.2 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus Mucin PF01456.17 EGC37572.1 - 1.5 8.8 26.9 2.7 8.0 26.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Pept_S41_N PF18294.1 EGC37572.1 - 2.3 8.3 11.3 1.1 9.4 6.9 2.9 2 1 0 2 2 2 0 Peptidase S41 N-terminal domain Chalcone_2 PF16035.5 EGC37573.1 - 6.1e-25 88.2 0.1 6.4e-24 84.9 0.1 2.1 1 1 0 1 1 1 1 Chalcone isomerase like Chalcone_3 PF16036.5 EGC37573.1 - 7.9e-05 22.8 0.0 0.0051 16.9 0.0 2.2 1 1 1 2 2 2 1 Chalcone isomerase-like T2SSS_2 PF16549.5 EGC37573.1 - 0.0099 15.9 0.1 0.023 14.7 0.1 1.6 1 0 0 1 1 1 1 Type II secretion system (T2SS) pilotin, S protein BORCS8 PF10167.9 EGC37573.1 - 0.03 14.3 0.2 0.72 9.8 0.0 2.4 2 0 0 2 2 2 0 BLOC-1-related complex sub-unit 8 Pik1 PF11522.8 EGC37573.1 - 0.39 10.7 5.8 0.18 11.8 0.5 3.0 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Apis_Csd PF11671.8 EGC37573.1 - 0.93 9.5 9.9 0.057 13.4 4.2 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein Lactamase_B_2 PF12706.7 EGC37574.1 - 1.5e-17 63.8 0.0 3.1e-14 53.0 0.0 2.4 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.6 EGC37574.1 - 1.1e-10 41.0 0.0 2.3e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.27 EGC37574.1 - 0.00079 19.5 0.0 0.0016 18.5 0.0 1.5 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily SWIRM-assoc_2 PF16496.5 EGC37575.1 - 4.1e-55 187.3 3.7 4.1e-55 187.3 3.7 4.1 3 2 1 5 5 2 1 SWIRM-associated domain at the N-terminal SWIRM PF04433.17 EGC37575.1 - 1.3e-29 102.3 0.1 4.8e-29 100.5 0.1 2.0 1 0 0 1 1 1 1 SWIRM domain SWIRM-assoc_1 PF16495.5 EGC37575.1 - 1.3e-23 82.7 8.8 1.3e-23 82.7 8.8 4.8 2 1 2 4 4 1 1 SWIRM-associated region 1 Myb_DNA-binding PF00249.31 EGC37575.1 - 9.4e-10 38.5 0.0 2.6e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Acetyltransf_2 PF00797.17 EGC37575.1 - 7.6e-08 32.4 0.0 7.6e-08 32.4 0.0 3.0 3 0 0 3 3 2 1 N-acetyltransferase Myb_DNA-bind_6 PF13921.6 EGC37575.1 - 4.6e-05 23.6 0.0 0.00037 20.7 0.0 2.7 1 0 0 1 1 1 1 Myb-like DNA-binding domain BRCT_2 PF16589.5 EGC37575.1 - 0.0001 22.6 1.5 0.00099 19.5 1.5 2.8 1 1 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC37575.1 - 0.014 15.8 3.5 0.044 14.2 2.6 2.5 2 1 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain LIG3_BRCT PF16759.5 EGC37575.1 - 0.025 14.9 1.4 0.055 13.8 0.1 2.3 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Chromo PF00385.24 EGC37575.1 - 2.2 8.3 4.7 28 4.7 1.9 2.9 2 0 0 2 2 2 0 Chromo (CHRromatin Organisation MOdifier) domain DUF4428 PF14471.6 EGC37575.1 - 3.3 7.7 4.9 18 5.3 4.9 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4428) Trypan_PARP PF05887.11 EGC37575.1 - 8.5 6.4 8.5 49 3.9 8.5 2.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Acetyltransf_2 PF00797.17 EGC37576.1 - 5.2e-16 59.2 0.0 7.7e-16 58.6 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase SNARE PF05739.19 EGC37577.1 - 9.2e-08 32.0 0.2 2.9e-07 30.4 0.2 1.9 1 0 0 1 1 1 1 SNARE domain Syntaxin PF00804.25 EGC37577.1 - 2.6e-07 30.5 9.3 6.1e-05 22.8 1.3 2.3 2 0 0 2 2 2 2 Syntaxin RNA_pol_Rpc82 PF05645.13 EGC37577.1 - 0.011 15.5 2.2 0.011 15.5 2.2 1.9 2 1 0 2 2 2 0 RNA polymerase III subunit RPC82 TA0956 PF11513.8 EGC37577.1 - 0.042 14.1 0.2 0.11 12.8 0.2 1.8 1 0 0 1 1 1 0 Thermoplasma acidophilum protein TA0956 MCPsignal PF00015.21 EGC37577.1 - 0.085 12.7 1.0 0.22 11.3 0.3 2.1 3 0 0 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain DUF3870 PF12986.7 EGC37577.1 - 0.11 12.7 0.1 0.32 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Syntaxin_2 PF14523.6 EGC37577.1 - 0.19 12.1 15.1 0.062 13.7 7.5 2.8 2 1 0 2 2 2 0 Syntaxin-like protein DUF3679 PF12438.8 EGC37577.1 - 0.82 9.4 0.0 0.82 9.4 0.0 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3679) OTU PF02338.19 EGC37578.1 - 5.7e-11 43.0 0.0 5.7e-11 43.0 0.0 1.9 2 1 0 2 2 2 1 OTU-like cysteine protease Myosin_head PF00063.21 EGC37578.1 - 0.057 11.6 2.6 0.088 11.0 2.6 1.2 1 0 0 1 1 1 0 Myosin head (motor domain) NAPRTase_C PF17956.1 EGC37578.1 - 0.5 10.8 9.1 1.5 9.3 2.5 3.5 3 0 0 3 3 3 0 Nicotinate phosphoribosyltransferase C-terminal domain Thioredoxin PF00085.20 EGC37579.1 - 7.8e-26 90.1 0.0 8.2e-26 90.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.6 EGC37579.1 - 6.7e-05 23.1 0.0 7.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.6 EGC37579.1 - 0.00026 21.4 0.1 0.007 16.8 0.1 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.6 EGC37579.1 - 0.004 17.3 0.1 0.0056 16.8 0.1 1.3 1 1 0 1 1 1 1 Thioredoxin-like OST3_OST6 PF04756.13 EGC37579.1 - 0.012 15.0 0.1 0.014 14.7 0.1 1.1 1 0 0 1 1 1 0 OST3 / OST6 family, transporter family Redoxin PF08534.10 EGC37579.1 - 0.014 15.1 0.1 0.017 14.9 0.1 1.4 1 1 0 1 1 1 0 Redoxin Thioredoxin_9 PF14595.6 EGC37579.1 - 0.037 13.8 0.0 0.047 13.5 0.0 1.2 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.21 EGC37579.1 - 0.048 13.6 0.1 0.067 13.1 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Glutaredoxin PF00462.24 EGC37579.1 - 0.058 13.6 0.1 0.083 13.1 0.1 1.3 1 0 0 1 1 1 0 Glutaredoxin Myosin_head PF00063.21 EGC37580.1 - 8.9e-248 823.9 6.1 1.1e-247 823.6 6.1 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.13 EGC37580.1 - 4.8e-39 134.0 4.7 9.3e-39 133.0 4.7 1.5 1 0 0 1 1 1 1 Unconventional myosin tail, actin- and lipid-binding SH3_1 PF00018.28 EGC37580.1 - 6.3e-17 60.9 0.1 1.4e-16 59.8 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC37580.1 - 1.1e-12 47.5 0.0 2.3e-12 46.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC37580.1 - 1.4e-07 31.1 0.0 4.1e-07 29.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain Phage_int_SAM_3 PF14659.6 EGC37580.1 - 0.0029 17.9 0.7 0.012 15.8 0.7 2.1 1 0 0 1 1 1 1 Phage integrase, N-terminal SAM-like domain AAA_16 PF13191.6 EGC37580.1 - 0.011 16.2 0.0 0.03 14.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.6 EGC37580.1 - 0.02 15.2 0.0 0.091 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Hpr_kinase_C PF07475.12 EGC37580.1 - 0.027 14.0 0.4 5.6 6.5 0.0 3.2 2 1 1 3 3 3 0 HPr Serine kinase C-terminal domain NACHT PF05729.12 EGC37580.1 - 0.06 13.3 0.1 0.13 12.2 0.1 1.5 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGC37580.1 - 0.11 12.9 0.0 0.51 10.8 0.0 2.2 1 0 0 1 1 1 0 RNA helicase Zeta_toxin PF06414.12 EGC37580.1 - 0.13 11.6 1.0 0.26 10.5 0.1 1.9 2 0 0 2 2 2 0 Zeta toxin NTPase_1 PF03266.15 EGC37580.1 - 0.15 12.0 0.0 0.38 10.7 0.0 1.7 1 0 0 1 1 1 0 NTPase Ank_5 PF13857.6 EGC37581.1 - 3.7e-22 78.1 0.9 3.4e-10 40.0 0.0 3.1 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC37581.1 - 1.2e-15 57.7 0.1 4.1e-06 27.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC37581.1 - 1.6e-14 54.2 0.1 4.1e-13 49.7 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.30 EGC37581.1 - 3.6e-14 52.5 0.1 6.4e-07 29.5 0.1 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGC37581.1 - 2.6e-09 36.5 0.0 0.0059 17.0 0.0 2.8 3 0 0 3 3 3 2 Ankyrin repeat DUF3246 PF11596.8 EGC37581.1 - 0.014 14.8 1.1 0.019 14.4 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3246) TPT PF03151.16 EGC37582.1 - 1.5e-13 50.7 19.8 1.9e-13 50.4 19.8 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family Gypsy PF07253.11 EGC37582.1 - 0.067 11.7 0.1 0.098 11.2 0.1 1.2 1 0 0 1 1 1 0 Gypsy protein Pox_I5 PF04713.12 EGC37582.1 - 1.1 9.4 10.0 0.055 13.5 1.9 2.9 3 1 1 4 4 4 0 Poxvirus protein I5 AAA_7 PF12775.7 EGC37583.1 - 4.6e-10 39.3 0.4 0.018 14.6 0.0 4.8 4 0 0 4 4 4 3 P-loop containing dynein motor region AAA PF00004.29 EGC37583.1 - 2.3e-07 31.3 0.9 3.2e-05 24.4 0.0 4.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC37583.1 - 9.6e-05 22.7 0.3 0.86 9.9 0.0 5.1 5 0 0 5 5 5 2 AAA domain AAA_5 PF07728.14 EGC37583.1 - 0.00028 20.9 0.1 4.1 7.4 0.0 4.3 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC37583.1 - 0.0023 18.3 0.0 0.05 14.0 0.0 3.2 2 0 0 2 2 2 1 AAA ATPase domain T2SSE PF00437.20 EGC37583.1 - 0.039 13.0 0.0 0.093 11.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein GalP_UDP_transf PF01087.22 EGC37585.1 - 0.0038 17.7 0.0 0.005 17.3 0.0 1.1 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain SLM4 PF16818.5 EGC37585.1 - 0.0071 16.3 0.1 0.012 15.6 0.1 1.4 1 0 0 1 1 1 1 Protein SLM4 DUF4162 PF13732.6 EGC37585.1 - 0.059 14.1 0.2 0.61 10.8 0.0 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4162) AAA_7 PF12775.7 EGC37587.1 - 1.4e-10 40.9 1.6 0.011 15.2 0.0 5.0 5 0 0 5 5 5 3 P-loop containing dynein motor region AAA PF00004.29 EGC37587.1 - 6.6e-08 33.0 0.1 2.8e-05 24.5 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC37587.1 - 0.00018 21.8 1.0 0.87 9.9 0.0 5.4 5 1 0 5 5 5 1 AAA domain AAA_5 PF07728.14 EGC37587.1 - 0.001 19.0 0.0 4.1 7.4 0.0 4.2 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC37587.1 - 0.0023 18.3 0.0 0.075 13.4 0.0 3.5 4 0 0 4 4 4 1 AAA ATPase domain T2SSE PF00437.20 EGC37587.1 - 0.036 13.1 0.0 0.089 11.8 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein G-alpha PF00503.20 EGC37588.1 - 4.2e-117 391.3 1.2 4.9e-117 391.0 1.2 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC37588.1 - 4.9e-13 48.9 0.2 5.8e-09 35.7 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC37588.1 - 0.00025 20.5 3.1 0.029 13.7 0.1 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGC37588.1 - 0.012 15.8 0.1 8 6.7 0.0 2.6 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC37588.1 - 0.016 15.3 0.0 0.54 10.4 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC37588.1 - 0.12 11.9 0.1 2.1 7.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain zf-RING_2 PF13639.6 EGC37589.1 - 1.9e-08 34.5 17.3 1.9e-08 34.5 17.3 1.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37589.1 - 3.4e-06 26.8 15.8 3.4e-06 26.8 15.8 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37589.1 - 1.4e-05 24.9 15.0 2.9e-05 23.9 15.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37589.1 - 5.5e-05 23.4 12.5 5.5e-05 23.4 12.5 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger domain TFIIA PF03153.13 EGC37589.1 - 7.5e-05 22.9 21.7 7.5e-05 22.9 21.7 2.0 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.25 EGC37589.1 - 0.00026 20.8 19.9 0.00026 20.8 19.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC37589.1 - 0.0003 20.6 13.1 0.0009 19.1 13.1 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC37589.1 - 0.0037 17.2 11.9 0.0046 17.0 9.9 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_10 PF16685.5 EGC37589.1 - 0.0092 16.1 9.0 0.027 14.6 9.0 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC37589.1 - 0.23 11.7 15.0 0.99 9.6 15.0 2.2 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC37589.1 - 0.3 11.1 21.7 0.094 12.7 17.7 2.3 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_11 PF17123.5 EGC37589.1 - 0.57 10.0 9.9 1.2 9.0 9.9 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC37589.1 - 8.7 6.5 16.1 0.39 10.8 9.3 2.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cytochrom_B558a PF05038.13 EGC37590.1 - 5e-10 39.3 9.4 4.5e-09 36.2 0.5 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit Pkinase PF00069.25 EGC37594.1 - 1.4e-72 244.3 0.0 1.4e-72 244.3 0.0 2.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37594.1 - 1e-44 152.8 0.0 1e-44 152.8 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT PF02985.22 EGC37594.1 - 2.7e-07 30.2 0.0 0.2 12.0 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Pkinase_fungal PF17667.1 EGC37594.1 - 5.3e-06 25.5 0.1 5.3e-06 25.5 0.1 2.6 2 0 0 2 2 2 1 Fungal protein kinase HEAT_2 PF13646.6 EGC37594.1 - 2.6e-05 24.5 0.0 0.0015 18.8 0.0 2.5 2 0 0 2 2 2 1 HEAT repeats Kinase-like PF14531.6 EGC37594.1 - 3e-05 23.5 0.0 3e-05 23.5 0.0 3.1 3 1 0 3 3 3 1 Kinase-like HEAT_EZ PF13513.6 EGC37594.1 - 0.00019 21.8 0.0 0.56 10.8 0.0 4.0 3 0 0 3 3 3 1 HEAT-like repeat APH PF01636.23 EGC37594.1 - 0.0087 16.0 0.9 0.016 15.2 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family Coiled PF05710.12 EGC37595.1 - 0.0066 17.2 3.1 0.0066 17.2 3.1 1.1 1 0 0 1 1 1 1 Coiled coil COPI_C PF06957.11 EGC37596.1 - 3.2e-135 451.0 0.0 4.3e-135 450.6 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus Coatomer_WDAD PF04053.14 EGC37596.1 - 9.2e-121 404.0 2.5 2e-120 402.8 2.5 1.6 1 0 0 1 1 1 1 Coatomer WD associated region WD40 PF00400.32 EGC37596.1 - 1.4e-43 146.0 9.5 3.8e-08 33.8 0.1 8.1 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37596.1 - 1.1e-07 32.1 0.1 0.022 15.0 0.0 4.6 3 1 2 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC37596.1 - 0.0049 15.6 0.6 1.4 7.4 0.1 3.2 2 1 0 3 3 3 2 Nucleoporin Nup120/160 TPR_2 PF07719.17 EGC37596.1 - 0.042 14.0 0.1 20 5.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37596.1 - 0.12 12.2 0.0 2.5 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.27 EGC37597.1 - 1.1e-19 71.0 1.5 8.4e-19 68.1 1.4 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.6 EGC37597.1 - 3.9e-17 63.4 0.1 5.3e-06 27.0 0.0 3.4 2 1 1 3 3 3 3 Sulfotransferase family DUF3573 PF12097.8 EGC37597.1 - 0.0027 16.6 0.1 0.0036 16.2 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3573) SRP9-21 PF05486.12 EGC37598.1 - 2.8e-11 43.7 0.5 1.7e-09 37.9 0.5 2.0 1 1 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Lipoprotein_21 PF14041.6 EGC37598.1 - 0.04 14.0 0.1 0.045 13.9 0.1 1.2 1 0 0 1 1 1 0 LppP/LprE lipoprotein RRM_1 PF00076.22 EGC37600.1 - 2e-18 66.0 0.1 3.5e-18 65.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) U1snRNP70_N PF12220.8 EGC37600.1 - 1.3e-15 57.8 7.3 1.3e-15 57.8 7.3 4.4 3 2 1 4 4 4 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal PRP38_assoc PF12871.7 EGC37600.1 - 0.016 15.8 42.2 0.016 15.8 42.2 5.2 2 1 2 5 5 5 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term WD40 PF00400.32 EGC37601.1 - 5.3e-35 118.9 35.4 3.3e-06 27.7 0.3 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box PF00646.33 EGC37601.1 - 1.8e-05 24.5 0.1 3.4e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain ANAPC4_WD40 PF12894.7 EGC37601.1 - 4.2e-05 23.8 5.3 2.1 8.7 0.1 5.2 3 1 3 6 6 6 3 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EGC37601.1 - 0.00013 21.8 0.2 0.00024 20.9 0.2 1.5 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.6 EGC37601.1 - 0.0091 15.6 1.9 0.035 13.7 1.5 2.0 1 1 1 2 2 2 1 PQQ-like domain IF4E PF01652.18 EGC37602.1 - 4.3e-47 159.9 0.7 6.3e-47 159.3 0.7 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E FH2 PF02181.23 EGC37603.1 - 8.9e-87 291.6 12.9 8.9e-87 291.6 12.9 3.0 3 0 0 3 3 3 1 Formin Homology 2 Domain FHA PF00498.26 EGC37603.1 - 5.5e-10 39.5 0.7 2.5e-08 34.1 0.7 3.2 1 1 0 1 1 1 1 FHA domain Drf_FH3 PF06367.16 EGC37603.1 - 1.6e-08 34.4 3.4 1.6e-08 34.4 3.4 4.5 5 0 0 5 5 5 1 Diaphanous FH3 Domain O-antigen_lig PF13425.6 EGC37604.1 - 0.012 14.5 9.7 0.013 14.3 9.7 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein HCO3_cotransp PF00955.21 EGC37604.1 - 0.37 9.6 4.5 0.42 9.4 4.5 1.1 1 0 0 1 1 1 0 HCO3- transporter family CSG2 PF16965.5 EGC37604.1 - 2.8 6.8 7.4 4.5 6.1 7.4 1.4 1 1 0 1 1 1 0 Ceramide synthase regulator DOT1 PF08123.13 EGC37605.1 - 1.1e-27 96.9 1.4 3.6e-27 95.2 0.0 2.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_25 PF13649.6 EGC37605.1 - 8.8e-06 26.3 0.0 3e-05 24.7 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Integrase_H2C2 PF17921.1 EGC37605.1 - 0.0022 18.1 0.8 0.0047 17.0 0.8 1.5 1 0 0 1 1 1 1 Integrase zinc binding domain Methyltransf_11 PF08241.12 EGC37605.1 - 0.0066 17.1 0.1 0.044 14.4 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC37605.1 - 0.018 14.9 0.4 0.19 11.6 0.0 2.8 2 0 0 2 2 2 0 Methyltransferase domain AdoMet_MTase PF07757.13 EGC37605.1 - 0.072 13.4 0.0 0.29 11.5 0.0 2.0 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Hamartin PF04388.12 EGC37606.1 - 0.21 10.2 5.3 0.3 9.7 5.3 1.1 1 0 0 1 1 1 0 Hamartin protein ELMO_CED12 PF04727.13 EGC37607.1 - 2.2e-31 109.3 0.2 9.3e-31 107.3 0.2 2.2 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_C1 PF00112.23 EGC37608.1 - 2e-41 142.5 0.4 2e-41 142.5 0.4 2.2 2 1 0 2 2 2 1 Papain family cysteine protease CBM49 PF09478.10 EGC37608.1 - 1.6e-17 63.5 6.1 4.4e-17 62.2 6.1 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.12 EGC37608.1 - 2.1e-11 44.1 7.9 2.1e-11 44.1 7.9 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) ETRAMP PF09716.10 EGC37608.1 - 0.17 12.0 1.0 0.48 10.5 0.3 2.0 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) zf-RING_2 PF13639.6 EGC37609.1 - 7e-11 42.3 14.7 1.6e-10 41.1 14.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37609.1 - 4.3e-09 36.1 14.1 1.1e-08 34.8 14.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37609.1 - 6.7e-09 35.5 11.6 1.5e-08 34.4 11.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37609.1 - 3.7e-07 29.9 16.9 1.1e-06 28.4 16.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37609.1 - 4e-07 30.2 11.2 1.5e-06 28.4 11.2 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC37609.1 - 3.6e-05 23.6 14.8 0.00012 22.0 14.8 2.0 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC37609.1 - 0.0013 18.8 10.2 0.0037 17.2 10.2 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC37609.1 - 0.0017 18.5 13.4 0.0052 16.9 13.4 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC37609.1 - 0.0019 17.9 5.2 0.0043 16.8 5.2 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC37609.1 - 0.0037 17.0 13.1 0.01 15.6 13.1 1.8 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGC37609.1 - 0.006 16.4 13.1 0.027 14.3 12.8 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 DUF1272 PF06906.11 EGC37609.1 - 0.6 10.3 9.9 1.5 9.0 9.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-HC5HC2H PF13771.6 EGC37609.1 - 1.5 9.1 16.5 0.046 14.0 9.4 2.3 2 0 0 2 2 2 0 PHD-like zinc-binding domain DZR PF12773.7 EGC37609.1 - 2.3 8.3 12.4 5.9 7.0 12.4 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EGC37609.1 - 9.1 6.4 14.2 0.48 10.5 7.9 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Atg14 PF10186.9 EGC37610.1 - 0.00011 21.4 5.1 0.00014 21.1 5.1 1.2 1 0 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 Tropomyosin_1 PF12718.7 EGC37610.1 - 0.00034 20.8 14.9 0.00073 19.7 14.9 1.5 1 0 0 1 1 1 1 Tropomyosin like Leu_zip PF15294.6 EGC37610.1 - 0.00048 19.7 8.0 0.00098 18.7 8.0 1.5 1 0 0 1 1 1 1 Leucine zipper TMCO5 PF14992.6 EGC37610.1 - 0.00069 19.3 15.3 0.0012 18.5 12.5 2.1 2 0 0 2 2 2 1 TMCO5 family GAS PF13851.6 EGC37610.1 - 0.0008 18.8 14.7 0.0015 17.9 14.7 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding Mod_r PF07200.13 EGC37610.1 - 0.0019 18.3 9.1 0.0035 17.4 9.1 1.4 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Golgin_A5 PF09787.9 EGC37610.1 - 0.011 15.2 8.7 0.021 14.3 8.7 1.4 1 0 0 1 1 1 0 Golgin subfamily A member 5 Prefoldin PF02996.17 EGC37610.1 - 0.018 14.9 0.4 0.018 14.9 0.4 2.5 2 0 0 2 2 2 0 Prefoldin subunit Fez1 PF06818.15 EGC37610.1 - 0.023 15.1 7.0 0.039 14.4 7.0 1.5 1 0 0 1 1 1 0 Fez1 DivIC PF04977.15 EGC37610.1 - 0.026 14.3 16.4 0.72 9.7 3.3 3.3 1 1 2 3 3 3 0 Septum formation initiator DUF4472 PF14739.6 EGC37610.1 - 0.033 14.9 12.6 0.11 13.2 12.6 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4472) DUF724 PF05266.14 EGC37610.1 - 0.034 14.0 7.8 0.069 13.0 7.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) HAUS-augmin3 PF14932.6 EGC37610.1 - 0.069 12.7 6.8 0.11 12.0 6.8 1.3 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 CENP-H PF05837.12 EGC37610.1 - 0.082 13.3 13.1 0.046 14.1 10.4 1.9 1 1 1 2 2 2 0 Centromere protein H (CENP-H) Imm7 PF15585.6 EGC37610.1 - 0.11 12.8 1.2 0.25 11.7 1.2 1.5 1 0 0 1 1 1 0 Immunity protein 7 UPF0242 PF06785.11 EGC37610.1 - 0.2 11.7 10.4 0.32 11.1 10.4 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus CALCOCO1 PF07888.11 EGC37610.1 - 0.26 10.1 10.3 0.35 9.7 10.3 1.1 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like DUF4559 PF15112.6 EGC37610.1 - 0.27 10.9 10.0 0.11 12.1 5.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4559) DUF3450 PF11932.8 EGC37610.1 - 0.32 10.3 6.5 0.52 9.6 6.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF16 PF01519.16 EGC37610.1 - 0.36 11.3 16.6 0.047 14.2 10.9 2.5 2 2 0 2 2 2 0 Protein of unknown function DUF16 ATG16 PF08614.11 EGC37610.1 - 0.45 10.7 14.4 0.87 9.8 14.4 1.4 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) AKNA PF12443.8 EGC37610.1 - 0.48 11.1 4.6 0.47 11.1 2.4 2.1 1 1 1 2 2 2 0 AT-hook-containing transcription factor APG6_N PF17675.1 EGC37610.1 - 0.53 10.8 15.5 3.5 8.1 6.8 2.3 1 1 1 2 2 2 0 Apg6 coiled-coil region GrpE PF01025.19 EGC37610.1 - 0.86 9.2 17.3 0.067 12.9 8.9 2.6 2 1 1 3 3 3 0 GrpE SlyX PF04102.12 EGC37610.1 - 1.1 9.9 9.1 0.44 11.2 1.2 2.4 1 1 1 2 2 2 0 SlyX DUF4337 PF14235.6 EGC37610.1 - 1.2 9.3 3.8 2.1 8.5 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF1664 PF07889.12 EGC37610.1 - 1.7 8.7 8.0 1.6 8.7 3.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.6 EGC37610.1 - 2.2 8.4 8.9 2.7 8.1 0.9 2.3 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 TolA_bind_tri PF16331.5 EGC37610.1 - 2.6 8.2 8.7 6.4 6.9 7.4 2.2 2 0 0 2 2 2 0 TolA binding protein trimerisation bZIP_1 PF00170.21 EGC37610.1 - 2.7 8.1 19.1 0.33 11.1 9.5 3.1 1 1 2 3 3 3 0 bZIP transcription factor FAM76 PF16046.5 EGC37610.1 - 4 6.7 15.3 0.65 9.3 11.9 1.5 2 0 0 2 2 2 0 FAM76 protein Csm1_N PF18504.1 EGC37610.1 - 4.3 7.7 15.7 4.7 7.6 1.0 3.0 1 1 2 3 3 3 0 Csm1 N-terminal domain YabA PF06156.13 EGC37610.1 - 7.3 7.3 13.5 18 6.0 12.3 2.3 1 1 1 2 2 1 0 Initiation control protein YabA DUF2205 PF10224.9 EGC37610.1 - 7.8 6.6 15.1 7 6.7 2.4 2.9 1 1 1 2 2 2 0 Short coiled-coil protein RasGEF PF00617.19 EGC37612.1 - 4.5e-51 173.5 0.7 2.7e-50 171.0 0.0 2.9 3 0 0 3 3 3 1 RasGEF domain LRR_8 PF13855.6 EGC37612.1 - 1.9e-30 104.4 48.1 4.6e-10 39.1 4.6 7.6 3 1 4 7 7 7 7 Leucine rich repeat LRR_4 PF12799.7 EGC37612.1 - 1.6e-21 76.0 74.0 6.3e-07 29.6 1.8 10.0 10 0 0 10 10 9 6 Leucine Rich repeats (2 copies) RasGEF_N PF00618.20 EGC37612.1 - 8.9e-11 42.0 0.3 8.9e-11 42.0 0.3 2.9 2 0 0 2 2 2 1 RasGEF N-terminal motif Drf_GBD PF06371.13 EGC37612.1 - 2.9e-10 40.0 1.3 2e-09 37.3 1.0 2.6 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain FERM_f0 PF16511.5 EGC37612.1 - 6.7e-07 29.5 1.1 0.73 10.2 0.0 4.4 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM Drf_FH3 PF06367.16 EGC37612.1 - 6.7e-06 25.9 0.5 3.3e-05 23.6 0.5 2.2 1 0 0 1 1 1 1 Diaphanous FH3 Domain FERM_N PF09379.10 EGC37612.1 - 0.0043 17.0 0.0 0.77 9.7 0.0 2.7 2 0 0 2 2 2 1 FERM N-terminal domain LRR_9 PF14580.6 EGC37612.1 - 0.0057 16.2 19.3 0.05 13.1 4.9 5.0 4 1 0 5 5 5 2 Leucine-rich repeat LRR_1 PF00560.33 EGC37612.1 - 0.029 14.9 38.8 0.42 11.4 0.1 11.6 11 2 0 11 11 10 0 Leucine Rich Repeat GED PF02212.18 EGC37612.1 - 0.6 10.3 4.7 20 5.4 0.5 3.1 2 0 0 2 2 2 0 Dynamin GTPase effector domain LRR_6 PF13516.6 EGC37612.1 - 1.7 8.9 52.0 1.6 9.0 0.1 11.9 12 0 0 12 12 11 0 Leucine Rich repeat DHO_dh PF01180.21 EGC37613.1 - 3.6e-34 118.3 0.0 2.1e-33 115.8 0.0 2.1 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.6 EGC37613.1 - 4.8e-24 84.2 12.3 4.8e-24 84.2 12.3 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_20 PF14691.6 EGC37613.1 - 1.4e-11 44.2 0.0 1.4e-11 44.2 0.0 2.7 3 0 0 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Pyr_redox_2 PF07992.14 EGC37613.1 - 8.1e-11 41.7 0.0 2.2e-09 37.0 0.0 1.9 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Dus PF01207.17 EGC37613.1 - 5e-07 29.1 0.0 2.9e-06 26.6 0.0 2.1 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Fer4 PF00037.27 EGC37613.1 - 7e-07 28.8 21.6 0.0022 17.7 3.0 3.8 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_6 PF12837.7 EGC37613.1 - 1.1e-06 28.4 17.8 0.0001 22.2 3.0 3.2 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.7 EGC37613.1 - 5.7e-06 26.8 8.5 5.7e-06 26.8 8.5 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_2 PF12797.7 EGC37613.1 - 1.1e-05 25.2 19.9 0.0037 17.3 3.5 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain NAD_binding_8 PF13450.6 EGC37613.1 - 1.4e-05 25.2 0.0 4.2e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGC37613.1 - 5.8e-05 22.5 0.0 0.11 11.7 0.0 2.7 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC37613.1 - 0.00012 22.5 0.0 0.65 10.6 0.0 2.8 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.6 EGC37613.1 - 0.00048 20.2 10.9 0.00048 20.2 10.9 2.4 2 0 0 2 2 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGC37613.1 - 0.00055 20.0 11.2 0.00055 20.0 11.2 2.8 2 1 1 3 3 3 2 4Fe-4S dicluster domain Fer4_13 PF13370.6 EGC37613.1 - 0.02 15.4 13.8 0.11 13.0 3.8 3.3 2 0 0 2 2 2 0 4Fe-4S single cluster domain of Ferredoxin I Fer4_17 PF13534.6 EGC37613.1 - 0.039 14.5 10.9 0.39 11.3 0.6 3.0 3 0 0 3 3 2 0 4Fe-4S dicluster domain Fer4_4 PF12800.7 EGC37613.1 - 1 10.0 25.7 0.15 12.6 3.5 3.7 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_16 PF13484.6 EGC37613.1 - 3.9 8.5 17.8 1.5 9.9 1.8 3.6 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain COG4 PF08318.12 EGC37614.1 - 1.9e-45 155.4 16.7 1.9e-45 155.4 16.7 2.6 3 0 0 3 3 3 1 COG4 transport protein Myb_DNA-bind_7 PF15963.5 EGC37614.1 - 0.18 11.7 0.0 0.18 11.7 0.0 4.1 3 1 1 4 4 4 0 Myb DNA-binding like DUF948 PF06103.11 EGC37614.1 - 1.1 9.5 3.9 4.1 7.7 0.2 3.7 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) DENN PF02141.21 EGC37615.1 - 2.1e-28 99.5 4.4 4.1e-26 92.1 0.4 3.1 3 0 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.18 EGC37615.1 - 1.3e-07 32.2 0.6 5.9e-07 30.2 0.6 2.2 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.19 EGC37615.1 - 5.4e-05 23.1 4.2 5.4e-05 23.1 4.2 1.9 2 0 0 2 2 2 1 dDENN domain DUF2852 PF11014.8 EGC37615.1 - 5.4 7.2 7.8 0.62 10.2 0.5 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2852) Peptidase_M20 PF01546.28 EGC37616.1 - 3.4e-22 79.1 0.0 1e-21 77.6 0.0 1.8 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC37616.1 - 1.2e-12 47.7 0.0 2.5e-12 46.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain RepA_C PF04796.12 EGC37617.1 - 0.27 11.2 2.2 0.49 10.4 2.2 1.3 1 0 0 1 1 1 0 Plasmid encoded RepA protein Fcf1 PF04900.12 EGC37618.1 - 6.5e-34 116.3 0.9 6.5e-34 116.3 0.9 1.5 2 0 0 2 2 2 1 Fcf1 PIN_9 PF18477.1 EGC37618.1 - 2.3e-12 47.2 0.0 3.7e-12 46.6 0.0 1.3 1 0 0 1 1 1 1 PIN like domain Cpn60_TCP1 PF00118.24 EGC37619.1 - 5.1e-136 454.2 0.6 1.3e-135 452.9 0.6 1.5 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.22 EGC37620.1 - 9e-29 99.1 2.3 6e-18 64.4 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC37620.1 - 1.2e-05 25.1 0.1 0.026 14.4 0.0 2.6 2 0 0 2 2 2 2 Occluded RNA-recognition motif TPR_14 PF13428.6 EGC37620.1 - 0.032 15.0 0.0 18 6.5 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Dapper PF15268.6 EGC37620.1 - 0.15 10.9 21.1 0.32 9.8 21.1 1.5 1 0 0 1 1 1 0 Dapper BRCT PF00533.26 EGC37620.1 - 0.2 12.1 2.2 0.88 10.0 0.0 3.2 3 0 0 3 3 3 0 BRCA1 C Terminus (BRCT) domain Suf PF05843.14 EGC37620.1 - 0.32 10.9 59.3 0.16 12.0 30.1 6.1 4 2 2 6 6 6 0 Suppressor of forked protein (Suf) SR-25 PF10500.9 EGC37620.1 - 2.2 7.8 36.3 3.6 7.2 33.6 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein SOBP PF15279.6 EGC37620.1 - 3.8 8.0 13.6 10 6.6 13.6 1.8 1 0 0 1 1 1 0 Sine oculis-binding protein DUF3915 PF13054.6 EGC37620.1 - 9.2 6.3 18.1 0.3 11.1 6.4 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3915) ARD PF03079.14 EGC37621.1 - 1.3e-45 155.4 1.4 1.5e-45 155.1 1.4 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.11 EGC37621.1 - 4.2e-10 39.2 0.0 6.4e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.19 EGC37621.1 - 1.4e-05 25.0 0.0 2.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.22 EGC37621.1 - 0.0013 18.3 0.0 0.0018 17.9 0.0 1.2 1 0 0 1 1 1 1 Cupin HHH_4 PF14490.6 EGC37622.1 - 0.034 14.1 0.9 0.086 12.8 0.2 2.1 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain XPG_N PF00752.17 EGC37623.1 - 1.3e-26 93.0 0.0 1.4e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 XPG N-terminal domain MMR_HSR1 PF01926.23 EGC37624.1 - 3.9e-14 52.7 0.4 9.4e-13 48.3 0.0 3.0 3 0 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC37624.1 - 3.8e-05 23.3 1.4 0.00012 21.7 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC37624.1 - 5e-05 23.3 5.6 0.052 13.5 0.0 3.3 4 0 0 4 4 4 2 RsgA GTPase cobW PF02492.19 EGC37624.1 - 0.034 13.7 0.1 0.15 11.6 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain N_BRCA1_IG PF16158.5 EGC37625.1 - 1.1e-30 106.3 1.9 1.6e-30 105.8 0.0 2.2 2 0 0 2 2 2 1 Ig-like domain from next to BRCA1 gene PB1 PF00564.24 EGC37625.1 - 3.6e-18 65.3 0.1 7.8e-18 64.2 0.1 1.6 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.17 EGC37625.1 - 6.2e-11 41.9 8.7 1.1e-10 41.1 8.7 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type C1_2 PF03107.16 EGC37625.1 - 0.00021 21.5 8.0 0.00058 20.1 8.0 1.7 1 0 0 1 1 1 1 C1 domain UBA_3 PF09288.10 EGC37625.1 - 0.036 13.9 0.0 0.12 12.2 0.0 1.9 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain O-antigen_lig PF13425.6 EGC37625.1 - 0.61 8.8 4.2 1 8.0 4.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein BUD22 PF09073.10 EGC37625.1 - 0.9 8.8 14.9 0.13 11.6 3.1 2.2 2 0 0 2 2 2 0 BUD22 GST_N_2 PF13409.6 EGC37626.1 - 6.4e-15 55.2 0.0 1.2e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC37626.1 - 3.4e-11 43.0 0.0 6.1e-11 42.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC37626.1 - 5.1e-05 23.4 1.1 0.00012 22.2 1.1 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC37626.1 - 0.00044 20.0 0.2 0.00093 19.0 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC37626.1 - 0.00047 20.5 0.0 0.0049 17.3 0.0 2.2 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC37626.1 - 0.0008 19.6 0.3 0.0016 18.6 0.3 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain aGPT-Pplase3 PF18746.1 EGC37626.1 - 0.0094 15.3 0.2 0.014 14.8 0.2 1.2 1 0 0 1 1 1 1 Alpha-glutamyl/putrescinyl thymine pyrophosphorylase clade 3 TPR_19 PF14559.6 EGC37627.1 - 1.5e-10 41.4 0.0 0.0033 17.9 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC37627.1 - 1.8e-08 34.5 2.1 1.2e-05 25.4 0.2 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.17 EGC37627.1 - 2.1e-05 24.3 0.4 0.58 10.4 0.0 4.2 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.6 EGC37627.1 - 0.0032 17.8 0.1 12 6.3 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC37627.1 - 0.046 14.6 0.1 2.6 9.1 0.0 3.7 4 2 2 6 6 4 0 Tetratricopeptide repeat TPR_9 PF13371.6 EGC37627.1 - 0.078 13.1 0.0 0.25 11.5 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Macoilin PF09726.9 EGC37627.1 - 0.47 9.0 7.6 0.67 8.4 7.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF4698 PF15769.5 EGC37627.1 - 0.54 9.3 4.0 0.84 8.6 4.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4698) TPR_8 PF13181.6 EGC37627.1 - 0.74 10.2 4.2 12 6.4 0.1 4.0 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC37627.1 - 1.3 9.8 5.1 52 4.8 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Mitofilin PF09731.9 EGC37627.1 - 1.7 7.4 3.7 1.4 7.6 1.6 1.8 2 0 0 2 2 2 0 Mitochondrial inner membrane protein Vma12 PF11712.8 EGC37628.1 - 0.32 11.0 7.3 4.7 7.3 7.3 2.4 1 1 0 1 1 1 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Phage_holin_3_6 PF07332.11 EGC37628.1 - 5.8 7.0 0.0 5.8 7.0 0.0 3.1 3 0 0 3 3 3 0 Putative Actinobacterial Holin-X, holin superfamily III Lipase_3 PF01764.25 EGC37629.1 - 1.1e-30 106.3 0.0 1.6e-30 105.8 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.8 EGC37629.1 - 0.0032 17.1 0.1 0.009 15.6 0.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGC37629.1 - 0.019 15.6 0.0 0.022 15.4 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family PGAP1 PF07819.13 EGC37629.1 - 0.019 14.7 0.2 0.054 13.2 0.1 1.6 1 1 1 2 2 2 0 PGAP1-like protein DUF676 PF05057.14 EGC37629.1 - 0.043 13.3 0.0 0.07 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Hydrolase_4 PF12146.8 EGC37629.1 - 0.088 12.1 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DLH PF01738.18 EGC37629.1 - 0.13 11.8 0.0 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Dienelactone hydrolase family ATE_C PF04377.15 EGC37630.1 - 1.5e-50 171.3 2.9 1.5e-50 171.3 2.9 2.3 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.13 EGC37630.1 - 9.5e-24 83.6 2.6 1.9e-23 82.7 0.7 2.6 2 0 0 2 2 2 1 Arginine-tRNA-protein transferase, N terminus Ins134_P3_kin_N PF17927.1 EGC37630.1 - 0.012 16.0 0.5 13 6.3 0.0 3.5 2 1 1 3 3 3 0 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain Dickkopf_N PF04706.12 EGC37631.1 - 0.0036 17.7 15.3 0.013 16.0 2.9 3.0 3 1 1 4 4 4 2 Dickkopf N-terminal cysteine-rich region Nodulin_late PF07127.11 EGC37631.1 - 0.086 13.2 0.5 0.086 13.2 0.5 3.6 3 1 1 4 4 4 0 Late nodulin protein Kelch_4 PF13418.6 EGC37632.1 - 3e-35 120.0 15.3 4.6e-08 32.9 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC37632.1 - 7.9e-30 102.3 15.6 1.3e-08 34.7 0.2 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.6 EGC37632.1 - 2.1e-27 94.8 14.4 2.8e-10 40.2 0.0 7.1 7 0 0 7 7 7 3 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC37632.1 - 1.3e-25 88.7 9.1 1.2e-07 31.2 0.0 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_6 PF13964.6 EGC37632.1 - 9.1e-25 86.1 15.5 5.1e-06 26.6 0.0 6.1 6 0 0 6 6 6 4 Kelch motif Kelch_2 PF07646.15 EGC37632.1 - 1.7e-21 75.3 12.8 1.2e-05 25.1 0.3 6.3 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.6 EGC37632.1 - 4.2e-12 45.7 9.3 7.3e-12 45.0 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC37632.1 - 1.1e-06 28.4 9.3 2.2e-06 27.4 9.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC37632.1 - 0.00075 19.8 11.4 0.0014 18.9 11.4 1.5 1 0 0 1 1 1 1 Ring finger domain PKcGMP_CC PF16808.5 EGC37632.1 - 0.006 16.4 1.0 0.24 11.3 1.0 2.5 1 1 0 1 1 1 1 Coiled-coil N-terminus of cGMP-dependent protein kinase zf-RING_5 PF14634.6 EGC37632.1 - 0.0078 16.2 9.6 0.016 15.2 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Hexapep PF00132.24 EGC37632.1 - 0.058 13.1 0.3 0.14 11.9 0.3 1.7 1 0 0 1 1 1 0 Bacterial transferase hexapeptide (six repeats) DUF4108 PF13390.6 EGC37632.1 - 0.75 9.7 6.2 1.2 9.0 3.2 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4108) DUF1732 PF08340.11 EGC37633.1 - 0.018 15.0 1.4 0.046 13.7 1.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1732) AI-2E_transport PF01594.16 EGC37633.1 - 0.2 10.8 1.3 0.3 10.2 1.3 1.3 1 0 0 1 1 1 0 AI-2E family transporter Pox_LP_H2 PF03356.15 EGC37633.1 - 0.33 10.8 3.3 0.099 12.5 0.3 1.7 2 0 0 2 2 2 0 Viral late protein H2 DENN PF02141.21 EGC37634.1 - 2.1e-45 155.0 6.7 3.6e-45 154.2 5.1 2.4 2 0 0 2 2 2 1 DENN (AEX-3) domain LIM PF00412.22 EGC37634.1 - 2.9e-13 49.8 39.3 1.2e-05 25.4 12.4 3.8 3 0 0 3 3 3 3 LIM domain uDENN PF03456.18 EGC37634.1 - 9.4e-08 32.7 0.0 7.3e-07 29.8 0.0 2.7 1 0 0 1 1 1 1 uDENN domain SelP_N PF04592.14 EGC37634.1 - 0.25 10.7 31.9 0.78 9.1 31.9 1.8 1 0 0 1 1 1 0 Selenoprotein P, N terminal region Ac76 PF05814.11 EGC37635.1 - 0.13 12.3 0.2 0.28 11.2 0.2 1.5 1 0 0 1 1 1 0 Orf76 (Ac76) Ku_PK_bind PF08785.11 EGC37636.1 - 0.095 12.9 5.0 0.061 13.5 2.6 2.0 2 0 0 2 2 2 0 Ku C terminal domain like TetR_C_4 PF08359.11 EGC37636.1 - 0.1 12.7 2.7 0.21 11.7 0.2 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region DUF1840 PF08895.11 EGC37636.1 - 0.9 9.9 4.1 3.8 7.9 3.0 2.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) DUF2115 PF09888.9 EGC37636.1 - 1.8 9.0 11.0 0.27 11.7 2.8 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Syntaxin-6_N PF09177.11 EGC37636.1 - 3.7 8.2 12.4 0.12 13.0 2.5 2.7 1 1 1 2 2 2 0 Syntaxin 6, N-terminal zf-RING_2 PF13639.6 EGC37637.1 - 3.4e-09 36.9 10.9 6.4e-09 36.0 10.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37637.1 - 6.2e-09 35.5 10.5 1.1e-08 34.7 10.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37637.1 - 1.5e-08 34.3 11.5 4.5e-08 32.8 11.5 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37637.1 - 5.6e-08 33.0 7.3 1.6e-07 31.5 7.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC37637.1 - 6.6e-07 29.1 7.3 1.1e-06 28.4 7.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37637.1 - 2.4e-05 24.2 10.4 4.6e-05 23.3 10.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC37637.1 - 9.8e-05 22.3 4.9 0.00023 21.1 4.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Methyltransf_2 PF00891.18 EGC37637.1 - 0.00025 20.4 0.1 0.0004 19.8 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase domain Prok-RING_4 PF14447.6 EGC37637.1 - 0.00068 19.5 7.1 0.0015 18.3 7.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC37637.1 - 0.00078 19.6 8.8 0.0019 18.3 8.8 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC37637.1 - 0.005 16.9 2.7 0.011 15.8 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC37637.1 - 0.013 15.2 9.2 0.028 14.2 9.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-UDP PF14569.6 EGC37637.1 - 0.23 11.6 2.8 0.62 10.2 2.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger Zn_ribbon_17 PF17120.5 EGC37637.1 - 0.65 9.7 7.5 1.1 8.9 7.5 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type SLC12 PF03522.15 EGC37637.1 - 0.71 8.8 15.2 1.4 7.8 15.2 1.5 1 0 0 1 1 1 0 Solute carrier family 12 zf-MIZ PF02891.20 EGC37637.1 - 3 7.7 8.0 6.2 6.7 8.0 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_11 PF17123.5 EGC37637.1 - 3.5 7.5 11.0 7.6 6.4 11.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger IBR PF01485.21 EGC37637.1 - 6.1 7.2 9.7 32 4.8 9.4 2.2 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Methyltransf_2 PF00891.18 EGC37638.1 - 1.2e-07 31.3 0.0 0.009 15.3 0.0 2.0 1 1 1 2 2 2 2 O-methyltransferase domain NmrA PF05368.13 EGC37639.1 - 1.4e-60 204.8 0.0 1.7e-60 204.5 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC37639.1 - 1.5e-14 54.3 0.0 2.1e-14 53.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC37639.1 - 3.7e-05 23.3 0.0 6.6e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC37639.1 - 0.00035 19.7 0.0 0.00067 18.7 0.0 1.5 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC37639.1 - 0.015 14.7 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase Sacchrp_dh_NADP PF03435.18 EGC37639.1 - 0.026 14.8 0.0 0.041 14.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain adh_short PF00106.25 EGC37639.1 - 0.041 13.3 0.0 0.062 12.8 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase F420_oxidored PF03807.17 EGC37639.1 - 0.043 14.4 0.0 0.074 13.6 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent IlvN PF07991.12 EGC37639.1 - 0.061 12.9 0.1 0.13 11.8 0.1 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, NADPH-binding domain HrcA_DNA-bdg PF03444.15 EGC37640.1 - 0.099 12.3 1.5 0.28 10.9 1.5 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF365 PF04033.12 EGC37641.1 - 0.08 13.2 0.8 0.1 12.9 0.8 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF365) Methyltr_RsmB-F PF01189.17 EGC37643.1 - 1.2e-32 113.2 1.2 1.8e-18 66.9 0.3 2.6 1 1 1 2 2 2 2 16S rRNA methyltransferase RsmB/F Methyltransf_31 PF13847.6 EGC37643.1 - 3.8e-06 26.8 2.2 6.9e-05 22.7 2.2 2.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC37643.1 - 1.4e-05 24.6 0.0 6.5e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.6 EGC37643.1 - 1.5e-05 25.6 0.0 3.4e-05 24.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGC37643.1 - 0.00012 21.9 0.0 0.00032 20.5 0.0 1.7 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGC37643.1 - 0.00016 21.9 1.5 0.0008 19.6 1.4 1.9 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.6 EGC37643.1 - 0.01 15.7 0.0 0.036 13.9 0.0 1.8 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_4 PF02390.17 EGC37643.1 - 0.025 14.0 0.0 0.025 14.0 0.0 2.4 2 0 0 2 2 2 0 Putative methyltransferase NLRC4_HD PF17889.1 EGC37643.1 - 0.74 10.2 0.0 0.74 10.2 0.0 3.1 3 0 0 3 3 3 0 NLRC4 helical domain FUSC_2 PF13515.6 EGC37646.1 - 5.5e-11 42.7 38.7 6.4e-09 36.0 19.2 2.7 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FNIP PF05725.12 EGC37647.1 - 7e-19 67.7 31.7 6.6e-09 35.8 3.9 4.0 3 1 1 4 4 4 4 FNIP Repeat Arm PF00514.23 EGC37648.1 - 3.1e-39 131.8 13.9 2.9e-06 27.1 0.0 12.0 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.6 EGC37648.1 - 2.6e-15 56.6 0.0 0.034 14.5 0.0 7.6 5 3 1 6 6 6 4 HEAT repeats HEAT PF02985.22 EGC37648.1 - 9.4e-14 50.4 18.6 0.036 14.3 0.1 11.1 13 0 0 13 13 12 3 HEAT repeat HEAT_EZ PF13513.6 EGC37648.1 - 1.4e-08 35.1 5.7 0.055 14.0 0.0 8.1 10 0 0 10 10 10 1 HEAT-like repeat Cnd1 PF12717.7 EGC37648.1 - 7.6e-08 32.6 20.8 0.025 14.6 0.5 5.1 1 1 3 4 4 4 4 non-SMC mitotic condensation complex subunit 1 RICTOR_V PF14668.6 EGC37648.1 - 2.7e-05 24.3 0.9 3.1 8.1 0.0 4.8 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.7 EGC37648.1 - 3.7e-05 24.2 7.8 0.35 11.5 0.1 4.5 4 1 0 5 5 4 2 Vacuolar 14 Fab1-binding region DUF3361 PF11841.8 EGC37648.1 - 0.0004 20.3 16.6 0.26 11.2 0.2 5.0 2 2 2 5 5 5 3 Domain of unknown function (DUF3361) V-ATPase_H_C PF11698.8 EGC37648.1 - 0.00047 20.3 10.4 4.1 7.5 0.1 5.6 3 2 3 6 6 6 2 V-ATPase subunit H Atx10homo_assoc PF09759.9 EGC37648.1 - 0.035 14.1 18.0 2.9 8.0 0.3 5.9 6 1 1 7 7 6 0 Spinocerebellar ataxia type 10 protein domain Tti2 PF10521.9 EGC37648.1 - 0.037 13.6 4.9 0.52 9.8 0.2 3.5 3 1 1 4 4 4 0 Tti2 family Peptidase_S41_N PF11918.8 EGC37648.1 - 0.047 13.9 1.2 0.25 11.6 0.2 2.6 2 1 1 3 3 3 0 N-terminal domain of Peptidase_S41 in eukaryotic IRBP RTP1_C1 PF10363.9 EGC37648.1 - 0.078 13.2 3.1 3.5 7.8 0.3 4.3 3 1 1 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 E2_bind PF08825.10 EGC37648.1 - 0.085 13.0 0.9 0.78 9.9 0.1 2.7 2 0 0 2 2 2 0 E2 binding domain IBN_N PF03810.19 EGC37648.1 - 0.47 10.4 3.0 4.4 7.3 0.1 3.7 3 0 0 3 3 3 0 Importin-beta N-terminal domain DHR-2 PF06920.13 EGC37649.1 - 2.9e-153 511.3 24.4 2.9e-153 511.3 24.4 2.4 2 0 0 2 2 2 1 Dock homology region 2 DOCK-C2 PF14429.6 EGC37649.1 - 5.3e-23 81.8 7.9 5.3e-23 81.8 7.9 3.8 3 1 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins DUF3385 PF11865.8 EGC37649.1 - 0.21 11.5 3.9 0.16 11.8 0.6 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_8 PF13181.6 EGC37649.1 - 1.2 9.5 3.6 41 4.7 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat CENP-H PF05837.12 EGC37650.1 - 1e-09 38.8 3.2 1e-09 38.8 3.2 2.8 1 1 0 2 2 2 1 Centromere protein H (CENP-H) YejG PF13989.6 EGC37650.1 - 0.0093 16.4 4.0 0.73 10.3 0.3 2.9 2 1 0 2 2 2 2 YejG-like protein SapB_2 PF03489.17 EGC37651.1 - 3.8e-21 74.9 8.4 4.5e-10 39.5 2.3 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC37651.1 - 1.7e-18 66.2 5.6 4.8e-10 39.2 0.8 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 1 NB PF04159.13 EGC37651.1 - 0.009 16.0 1.6 0.009 16.0 1.6 2.2 1 1 1 2 2 2 1 NB glycoprotein DUF3456 PF11938.8 EGC37651.1 - 0.099 13.1 7.5 9.3 6.8 0.3 3.6 2 1 2 4 4 4 0 TLR4 regulator and MIR-interacting MSAP MFS_2 PF13347.6 EGC37652.1 - 3.2e-08 32.6 6.2 1.5e-05 23.7 0.3 3.2 3 0 0 3 3 3 3 MFS/sugar transport protein GNAT_acetyltr_2 PF13718.6 EGC37654.1 - 1e-98 329.3 0.0 2.2e-98 328.2 0.0 1.6 1 0 0 1 1 1 1 GNAT acetyltransferase 2 tRNA_bind_2 PF13725.6 EGC37654.1 - 2.8e-73 246.5 11.5 2.8e-73 246.5 11.5 1.7 2 0 0 2 2 2 1 Possible tRNA binding domain Helicase_RecD PF05127.14 EGC37654.1 - 2.4e-62 209.9 0.0 8.1e-62 208.2 0.0 2.0 1 0 0 1 1 1 1 Helicase DUF1726 PF08351.11 EGC37654.1 - 5.5e-34 116.0 0.7 4.9e-33 112.9 0.1 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) zf-C3HC4_3 PF13920.6 EGC37654.1 - 4.5e-12 45.6 10.4 9.1e-12 44.7 10.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC37654.1 - 3.2e-05 23.7 10.8 8.7e-05 22.3 10.8 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC37654.1 - 0.0058 16.9 11.1 0.018 15.4 11.1 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGC37654.1 - 0.018 15.0 10.5 0.049 13.6 10.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Acetyltransf_1 PF00583.25 EGC37654.1 - 0.026 14.8 0.0 0.066 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC37654.1 - 0.028 14.8 0.0 0.077 13.4 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF2935 PF11155.8 EGC37654.1 - 0.49 10.7 3.2 1.8 8.9 0.2 3.3 3 1 0 3 3 3 0 Domain of unknown function (DUF2935) WD40 PF00400.32 EGC37655.1 - 2.9e-29 100.7 9.9 3.8e-08 33.9 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37655.1 - 3.4e-07 30.5 0.0 0.041 14.2 0.0 4.9 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain SOG2 PF10428.9 EGC37655.1 - 6.7 5.8 41.8 0.32 10.1 35.0 1.9 2 0 0 2 2 2 0 RAM signalling pathway protein SDA1 PF05285.12 EGC37656.1 - 1.3e-68 232.0 64.0 1.6e-68 231.7 53.2 2.1 2 0 0 2 2 2 2 SDA1 NUC130_3NT PF08158.12 EGC37656.1 - 1.2e-20 73.6 0.7 3.1e-20 72.2 0.7 1.8 1 0 0 1 1 1 1 NUC130/3NT domain FNIP PF05725.12 EGC37657.1 - 2.4e-34 117.2 70.1 2.2e-07 30.9 0.1 13.9 7 3 3 10 10 10 8 FNIP Repeat zf-RVT PF13966.6 EGC37658.1 - 0.0044 17.7 1.4 0.008 16.9 0.1 2.1 2 1 0 2 2 2 1 zinc-binding in reverse transcriptase DUF5055 PF16478.5 EGC37658.1 - 0.038 14.2 0.1 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF5055) IF4E PF01652.18 EGC37659.1 - 7.2e-30 103.9 3.5 2.1e-29 102.4 3.5 1.8 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cupin_8 PF13621.6 EGC37660.1 - 5.4e-43 147.5 1.0 6e-43 147.4 1.0 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.12 EGC37660.1 - 6.8e-09 35.6 0.0 1.6e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.22 EGC37660.1 - 0.0053 17.2 0.1 0.019 15.4 0.1 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase 3-PAP PF12578.8 EGC37661.1 - 0.13 12.1 3.5 0.21 11.3 3.5 1.3 1 0 0 1 1 1 0 Myotubularin-associated protein Nup54_C PF18437.1 EGC37661.1 - 0.18 11.8 0.2 0.36 10.8 0.2 1.5 1 0 0 1 1 1 0 Nup54 C-terminal interacting domain WSC PF01822.19 EGC37662.1 - 5e-27 93.9 28.3 2.7e-17 62.7 10.0 3.8 5 0 0 5 5 5 2 WSC domain CAP PF00188.26 EGC37662.1 - 3.1e-15 57.1 0.4 3.1e-15 57.1 0.4 2.7 3 1 0 3 3 3 1 Cysteine-rich secretory protein family SOG2 PF10428.9 EGC37662.1 - 0.6 9.3 18.4 0.89 8.7 18.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein Hamartin PF04388.12 EGC37662.1 - 3.1 6.4 11.9 4.2 5.9 11.9 1.2 1 0 0 1 1 1 0 Hamartin protein IBR PF01485.21 EGC37663.1 - 2.1e-07 31.0 47.9 1.5e-06 28.3 10.6 4.8 2 1 2 4 4 4 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGC37663.1 - 3.1e-06 27.1 5.9 3.1e-06 27.1 5.9 4.3 3 1 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGC37663.1 - 6.5e-05 23.2 10.1 6.5e-05 23.2 10.1 4.6 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGC37663.1 - 0.0012 18.7 8.5 0.0012 18.7 8.5 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37663.1 - 0.011 15.6 5.5 0.011 15.6 5.5 5.0 4 1 1 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Sacchrp_dh_C PF16653.5 EGC37664.1 - 9.9e-82 275.0 0.0 1.7e-81 274.2 0.0 1.4 1 1 0 1 1 1 1 Saccharopine dehydrogenase C-terminal domain Sacchrp_dh_NADP PF03435.18 EGC37664.1 - 9.1e-21 74.5 0.0 1.5e-20 73.8 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain NAD_binding_10 PF13460.6 EGC37664.1 - 0.0069 16.3 0.0 0.052 13.4 0.0 2.1 1 1 0 1 1 1 1 NAD(P)H-binding Shikimate_DH PF01488.20 EGC37664.1 - 0.089 12.9 0.0 0.15 12.1 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.25 EGC37667.1 - 3.5e-12 46.3 0.4 7.4e-12 45.2 0.4 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37667.1 - 9.7e-07 28.3 0.1 1.8e-06 27.5 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.22 EGC37667.1 - 0.00026 20.6 0.2 0.00052 19.7 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.23 EGC37667.1 - 0.00031 20.7 0.2 0.00062 19.8 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC37667.1 - 0.0065 15.8 0.1 0.012 15.0 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pex14_N PF04695.13 EGC37667.1 - 0.0065 17.1 3.2 0.011 16.4 3.2 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Seadorna_VP7 PF07387.11 EGC37667.1 - 0.0086 15.2 0.2 0.014 14.5 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 FAM75 PF14650.6 EGC37667.1 - 0.016 14.8 16.3 0.023 14.3 16.3 1.1 1 0 0 1 1 1 0 FAM75 family Choline_kinase PF01633.20 EGC37667.1 - 0.019 14.6 0.7 0.042 13.4 0.7 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Haspin_kinase PF12330.8 EGC37667.1 - 0.056 12.4 0.4 0.1 11.5 0.4 1.3 1 0 0 1 1 1 0 Haspin like kinase domain TMEM154 PF15102.6 EGC37667.1 - 0.072 13.0 0.7 0.12 12.3 0.7 1.2 1 0 0 1 1 1 0 TMEM154 protein family Pkinase_fungal PF17667.1 EGC37667.1 - 0.14 10.9 1.2 0.31 9.8 0.3 1.8 2 0 0 2 2 2 0 Fungal protein kinase FNIP PF05725.12 EGC37668.1 - 8.6e-141 457.9 75.3 1.1e-15 57.5 1.1 12.8 12 1 1 13 13 13 12 FNIP Repeat Phage_min_tail PF05939.13 EGC37668.1 - 0.0001 22.6 0.0 11 6.5 0.0 6.4 6 3 2 9 9 9 1 Phage minor tail protein HTH_ABP1_N PF18107.1 EGC37668.1 - 0.037 13.7 3.3 1.2e+02 2.5 0.0 6.1 9 0 0 9 9 9 0 Fission yeast centromere protein N-terminal domain W_rich_C PF07483.11 EGC37668.1 - 0.048 13.8 0.0 9 6.5 0.0 3.7 3 0 0 3 3 3 0 Tryptophan-rich Synechocystis species C-terminal domain MCM_OB PF17207.3 EGC37668.1 - 0.079 12.8 0.0 1.7e+02 2.0 0.0 4.6 4 1 0 5 5 5 0 MCM OB domain Peptidase_M22 PF00814.25 EGC37669.1 - 4.2e-84 282.4 0.0 4.9e-84 282.2 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family Carbam_trans_N PF02543.15 EGC37669.1 - 0.085 12.5 0.0 1.1 8.8 0.1 2.1 2 0 0 2 2 2 0 Carbamoyltransferase N-terminus PWI PF01480.17 EGC37670.1 - 0.0019 18.5 0.2 0.0055 17.0 0.2 1.9 1 1 0 1 1 1 1 PWI domain MPC PF03650.13 EGC37671.1 - 3.2e-19 69.1 0.4 3.7e-19 68.9 0.4 1.0 1 0 0 1 1 1 1 Mitochondrial pyruvate carriers bMG10 PF17973.1 EGC37672.1 - 4.1e-22 78.8 0.0 1.2e-21 77.2 0.0 1.9 1 0 0 1 1 1 1 Bacterial Alpha-2-macroglobulin MG10 domain ubiquitin PF00240.23 EGC37672.1 - 1.4e-20 72.8 1.1 3.2e-10 39.6 0.0 3.5 3 0 0 3 3 3 2 Ubiquitin family Rad60-SLD PF11976.8 EGC37672.1 - 3.8e-12 45.9 0.5 2.9e-06 27.0 0.1 3.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like A2M_BRD PF07703.14 EGC37672.1 - 1.9e-10 41.2 0.1 1.3e-09 38.5 0.1 2.6 2 0 0 2 2 2 1 Alpha-2-macroglobulin bait region domain A2M PF00207.22 EGC37672.1 - 1.3e-08 34.6 0.0 4.5e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Alpha-2-macroglobulin family Ubiquitin_5 PF18037.1 EGC37672.1 - 0.0056 17.0 0.3 5.9 7.3 0.0 3.1 2 0 0 2 2 2 2 Ubiquitin-like domain MG2 PF01835.19 EGC37672.1 - 0.05 14.1 0.0 1.2 9.6 0.0 3.2 2 1 0 2 2 2 0 MG2 domain TMEM154 PF15102.6 EGC37673.1 - 7.8 6.4 12.4 0.021 14.7 2.5 1.8 2 0 0 2 2 2 0 TMEM154 protein family TMEM154 PF15102.6 EGC37674.1 - 3.8e-05 23.6 3.3 8.9e-05 22.4 3.3 1.7 1 0 0 1 1 1 1 TMEM154 protein family BSD PF03909.17 EGC37675.1 - 4.4e-07 29.8 0.1 1.1e-06 28.5 0.1 1.7 1 0 0 1 1 1 1 BSD domain Menin PF05053.13 EGC37675.1 - 2.1 6.6 11.7 3 6.1 11.7 1.2 1 0 0 1 1 1 0 Menin Proteasome PF00227.26 EGC37676.1 - 4.3e-32 111.1 0.0 5.7e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit CtsR PF05848.11 EGC37676.1 - 0.11 12.4 0.2 0.57 10.1 0.0 2.2 3 0 0 3 3 3 0 CtsR N-terminal HTH domain AMP-binding PF00501.28 EGC37677.1 - 2e-96 323.2 0.0 2.6e-96 322.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC37677.1 - 2.3e-05 25.3 0.0 6.6e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CAP_N PF01213.19 EGC37677.1 - 0.02 14.4 0.1 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal SAM_1 PF00536.30 EGC37678.1 - 4.2e-08 33.5 0.3 0.00013 22.3 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC37678.1 - 3.4e-07 30.3 0.2 0.00041 20.4 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.16 EGC37678.1 - 0.013 15.5 0.0 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain SAM_Ste50p PF09235.10 EGC37678.1 - 0.025 14.8 0.7 0.078 13.2 0.1 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif PIG-L PF02585.17 EGC37679.1 - 5.2e-19 69.2 0.0 1.3e-18 67.9 0.0 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.20 EGC37679.1 - 8.6e-15 55.2 0.0 2.6e-14 53.7 0.0 1.7 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pox_polyA_pol_N PF12630.7 EGC37679.1 - 0.44 10.9 2.5 0.98 9.8 2.5 1.6 1 0 0 1 1 1 0 Poxvirus poly(A) polymerase N-terminal domain Robl_LC7 PF03259.17 EGC37680.1 - 0.0045 16.7 0.0 0.0083 15.9 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain 4HBT PF03061.22 EGC37681.1 - 8.3e-11 42.1 0.0 1.3e-10 41.5 0.0 1.3 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.6 EGC37681.1 - 0.021 14.9 0.0 0.027 14.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) FNIP PF05725.12 EGC37682.1 - 3e-41 139.3 35.1 2.1e-08 34.2 3.4 9.8 2 2 6 10 10 10 10 FNIP Repeat zf-B_box PF00643.24 EGC37682.1 - 0.00013 22.1 6.5 0.00028 21.0 6.5 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF2408 PF10303.9 EGC37682.1 - 0.19 12.3 12.5 0.032 14.8 2.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2408) IBR PF01485.21 EGC37682.1 - 3.7 7.9 9.4 11 6.4 9.4 1.8 1 1 0 1 1 1 0 IBR domain, a half RING-finger domain Mucin PF01456.17 EGC37682.1 - 5.1 7.1 14.2 9.5 6.2 14.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein LisH PF08513.11 EGC37683.1 - 0.086 12.8 0.0 1.3 9.1 0.0 2.5 2 0 0 2 2 2 0 LisH CS PF04969.16 EGC37685.1 - 3e-14 53.8 4.0 3e-14 53.8 4.0 1.6 2 0 0 2 2 2 1 CS domain SieB PF14163.6 EGC37685.1 - 0.0054 16.2 0.1 0.0096 15.4 0.1 1.4 1 0 0 1 1 1 1 Super-infection exclusion protein B DUF4981 PF16353.5 EGC37685.1 - 0.11 13.0 0.2 0.28 11.7 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function(DUF4981) SMC_N PF02463.19 EGC37686.1 - 5.7e-49 166.5 69.5 8.9e-47 159.4 69.5 4.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.13 EGC37686.1 - 7.8e-22 77.8 0.1 2.4e-21 76.2 0.1 1.9 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.6 EGC37686.1 - 5.8e-14 53.1 12.2 5.8e-14 53.1 12.2 6.7 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.6 EGC37686.1 - 8.9e-08 32.3 22.3 1.9e-05 24.7 1.6 4.3 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_15 PF13175.6 EGC37686.1 - 1.6e-06 28.1 28.6 1.6e-06 28.1 28.6 4.3 2 2 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGC37686.1 - 0.00058 19.6 0.0 0.0016 18.2 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain MscS_porin PF12795.7 EGC37686.1 - 0.0024 17.4 15.1 0.0024 17.4 15.1 6.2 3 2 2 6 6 6 1 Mechanosensitive ion channel porin domain ERM PF00769.19 EGC37686.1 - 0.0029 17.5 20.5 0.0029 17.5 20.5 5.5 2 2 2 5 5 5 1 Ezrin/radixin/moesin family ABC_tran PF00005.27 EGC37686.1 - 0.015 15.8 0.0 0.015 15.8 0.0 7.4 4 3 1 5 5 5 0 ABC transporter Fcf2 PF08698.11 EGC37687.1 - 1.2e-18 67.2 0.1 1.2e-18 67.2 0.1 2.6 1 1 1 2 2 2 1 Fcf2 pre-rRNA processing SapB_1 PF05184.15 EGC37688.1 - 7.4e-18 64.2 10.6 8.1e-12 44.9 1.0 3.4 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGC37688.1 - 3.1e-12 46.4 13.9 9.8e-11 41.6 1.2 3.3 4 0 0 4 4 4 2 Saposin-like type B, region 2 Thioredoxin PF00085.20 EGC37688.1 - 0.048 13.6 0.1 0.11 12.5 0.1 1.6 1 0 0 1 1 1 0 Thioredoxin zf-BED PF02892.15 EGC37688.1 - 0.11 12.5 0.8 6.7 6.8 0.2 2.5 2 0 0 2 2 2 0 BED zinc finger DUF3430 PF11912.8 EGC37689.1 - 4.1e-05 23.7 30.9 4.9e-05 23.5 30.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) ETRAMP PF09716.10 EGC37689.1 - 0.059 13.4 0.0 0.074 13.1 0.0 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PARG_cat PF05028.14 EGC37690.1 - 9.5e-131 436.1 0.0 1.8e-130 435.2 0.0 1.4 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Myb_DNA-binding PF00249.31 EGC37691.1 - 8.2e-20 70.7 1.5 8.9e-09 35.4 0.1 3.2 3 0 0 3 3 3 2 Myb-like DNA-binding domain DnaJ PF00226.31 EGC37691.1 - 1.5e-17 63.5 0.2 8.1e-17 61.1 0.2 2.4 1 0 0 1 1 1 1 DnaJ domain Mucin PF01456.17 EGC37691.1 - 0.0057 16.6 12.4 0.011 15.8 12.4 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.8 EGC37691.1 - 0.22 11.5 8.6 0.52 10.3 8.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myotub-related PF06602.14 EGC37692.1 - 2.8e-131 437.6 2.9 2.8e-131 437.6 2.9 2.6 4 0 0 4 4 4 1 Myotubularin-like phosphatase domain FERM_f0 PF16511.5 EGC37692.1 - 7.2e-10 39.0 11.7 0.0014 18.9 0.1 6.0 5 0 0 5 5 5 3 N-terminal or F0 domain of Talin-head FERM Y_phosphatase3 PF13350.6 EGC37692.1 - 0.011 15.7 0.0 0.023 14.6 0.0 1.5 1 0 0 1 1 1 0 Tyrosine phosphatase family DSPc PF00782.20 EGC37692.1 - 0.03 14.1 0.0 0.03 14.1 0.0 3.2 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain SUIM_assoc PF16619.5 EGC37692.1 - 0.78 9.9 6.6 0.11 12.6 1.3 2.3 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 adh_short PF00106.25 EGC37693.1 - 5.4e-43 146.7 0.1 7.3e-43 146.3 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37693.1 - 2e-31 109.3 0.0 2.6e-31 109.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC37693.1 - 6.9e-10 39.1 0.0 1e-09 38.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC37693.1 - 7e-05 22.4 0.6 0.00012 21.6 0.6 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.6 EGC37693.1 - 0.00036 20.5 0.0 0.00065 19.6 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGC37693.1 - 0.00062 19.3 0.3 0.00088 18.8 0.3 1.3 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGC37693.1 - 0.0052 16.4 0.1 0.012 15.2 0.1 1.6 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.17 EGC37693.1 - 0.0082 15.3 0.0 0.012 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain FliH PF02108.16 EGC37693.1 - 0.1 12.7 0.1 0.63 10.1 0.0 2.0 2 0 0 2 2 2 0 Flagellar assembly protein FliH CIAPIN1 PF05093.13 EGC37694.1 - 1.2e-20 73.9 19.0 9.9e-19 67.7 17.2 3.0 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis DRE2_N PF16803.5 EGC37694.1 - 0.00034 20.8 0.3 0.00082 19.6 0.1 1.8 1 1 1 2 2 2 1 Fe-S cluster assembly protein DRE2 N-terminus THEG4 PF15834.5 EGC37694.1 - 0.082 12.9 0.2 0.15 12.1 0.2 1.4 1 0 0 1 1 1 0 Testis highly expressed protein 4 baeRF_family12 PF18856.1 EGC37694.1 - 0.16 12.5 0.0 0.29 11.7 0.0 1.4 1 0 0 1 1 1 0 Bacterial archaeo-eukaryotic release factor family 12 MPC PF03650.13 EGC37696.1 - 4.3e-15 55.8 0.9 8.3e-15 54.9 0.2 1.6 2 0 0 2 2 2 1 Mitochondrial pyruvate carriers CENP-Q PF13094.6 EGC37697.1 - 0.27 11.4 13.6 0.27 11.4 13.6 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit TMEM51 PF15345.6 EGC37697.1 - 2 8.2 7.1 2.3 8.0 7.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 DUF4337 PF14235.6 EGC37697.1 - 9.5 6.3 11.2 9.8 6.3 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Mito_carr PF00153.27 EGC37698.1 - 6.4e-68 224.8 5.2 5.7e-24 83.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.11 EGC37698.1 - 0.063 11.6 0.1 0.08 11.2 0.1 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RhoGAP PF00620.27 EGC37699.1 - 1.3e-34 119.2 0.2 1.8e-33 115.5 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain zf-MYND PF01753.18 EGC37699.1 - 3.1e-10 39.9 7.3 5.2e-10 39.3 7.3 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.6 EGC37699.1 - 1.3 9.1 7.1 0.19 11.8 2.5 2.0 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.6 EGC37700.1 - 3.6e-10 39.6 7.9 6.6e-10 38.8 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC37700.1 - 5.4e-05 23.0 6.2 0.00013 21.7 6.2 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_2 PF13639.6 EGC37700.1 - 0.00013 22.2 9.3 0.00022 21.5 9.3 1.4 1 0 0 1 1 1 1 Ring finger domain DUF1272 PF06906.11 EGC37700.1 - 0.00088 19.3 4.2 0.0018 18.3 4.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_3 PF13920.6 EGC37700.1 - 0.0039 17.0 5.6 0.0072 16.2 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37700.1 - 0.0062 16.4 11.0 0.019 14.8 11.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37700.1 - 0.0079 16.0 8.4 0.014 15.3 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zinc-ribbons_6 PF07191.12 EGC37700.1 - 0.087 12.8 3.0 0.16 11.9 3.0 1.4 1 0 0 1 1 1 0 zinc-ribbons DUF3450 PF11932.8 EGC37700.1 - 2.3 7.5 9.5 4 6.7 9.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) WD40 PF00400.32 EGC37701.1 - 4e-64 211.0 18.5 2.5e-08 34.4 0.1 8.8 8 1 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37701.1 - 2.6e-24 85.3 1.9 0.00058 20.1 0.1 5.9 2 2 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain NLE PF08154.12 EGC37701.1 - 5.9e-15 55.6 3.0 1.2e-14 54.5 3.0 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.11 EGC37701.1 - 1.6e-12 47.8 0.4 0.0011 18.9 0.0 4.1 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Ge1_WD40 PF16529.5 EGC37701.1 - 2.1e-08 33.5 0.1 0.13 11.2 0.0 5.0 3 2 1 5 5 5 3 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC37701.1 - 8.9e-06 24.6 4.1 0.65 8.6 0.0 4.9 3 3 3 6 6 6 3 Nucleoporin Nup120/160 Nbas_N PF15492.6 EGC37701.1 - 1.6e-05 24.4 0.2 0.21 10.9 0.0 4.7 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal PD40 PF07676.12 EGC37701.1 - 0.00021 21.2 0.8 15 5.7 0.0 5.0 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat WD40_like PF17005.5 EGC37701.1 - 0.00078 18.9 0.0 2.4 7.4 0.0 3.8 4 0 0 4 4 4 1 WD40-like domain FCP1_C PF09309.10 EGC37701.1 - 0.018 14.9 0.0 3.5 7.4 0.0 3.0 3 0 0 3 3 3 0 FCP1, C-terminal Cytochrom_D1 PF02239.16 EGC37701.1 - 0.019 13.5 0.0 1.6 7.2 0.0 2.9 2 1 0 2 2 2 0 Cytochrome D1 heme domain Proteasome_A_N PF10584.9 EGC37701.1 - 0.67 9.7 2.7 3.7 7.3 0.0 3.1 3 0 0 3 3 3 0 Proteasome subunit A N-terminal signature dCMP_cyt_deam_1 PF00383.23 EGC37702.1 - 2.4e-05 24.1 0.0 3.3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RasGEF PF00617.19 EGC37703.1 - 9.5e-60 201.8 0.8 9.5e-60 201.8 0.8 2.3 2 1 1 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC37703.1 - 5.4e-26 90.9 3.1 6.8e-26 90.6 0.5 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif Nitrate_red_del PF02613.15 EGC37703.1 - 0.11 12.5 0.1 0.35 10.9 0.1 1.9 1 0 0 1 1 1 0 Nitrate reductase delta subunit LisH_TPL PF17814.1 EGC37703.1 - 0.63 9.7 3.1 0.92 9.2 1.0 2.3 2 0 0 2 2 2 0 LisH-like dimerisation domain zf-RING_2 PF13639.6 EGC37704.1 - 1.4e-10 41.4 8.1 2.6e-10 40.5 8.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC37704.1 - 7.3e-10 38.6 10.0 2.1e-09 37.1 10.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37704.1 - 9.6e-10 38.2 6.9 1.9e-09 37.2 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37704.1 - 1e-08 35.0 7.6 1.9e-08 34.1 7.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGC37704.1 - 2.3e-08 34.2 5.7 7.5e-08 32.5 5.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC37704.1 - 4.1e-08 32.9 8.5 7.6e-08 32.1 8.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC37704.1 - 5.7e-06 26.3 2.5 2.3e-05 24.3 2.3 2.2 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_11 PF17123.5 EGC37704.1 - 2.6e-05 23.8 6.5 5.7e-05 22.8 6.5 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC37704.1 - 4.5e-05 23.4 1.8 8.6e-05 22.5 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC37704.1 - 0.00037 20.2 8.6 0.00081 19.1 8.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGC37704.1 - 0.0022 17.8 6.1 0.0052 16.6 6.1 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC37704.1 - 0.011 15.9 9.2 0.026 14.7 9.2 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_10 PF16685.5 EGC37704.1 - 0.11 12.7 4.7 0.28 11.3 4.7 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGC37704.1 - 0.12 12.1 6.4 0.2 11.3 6.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_6 PF14835.6 EGC37704.1 - 0.22 11.4 2.5 0.62 10.0 2.5 1.7 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-P11 PF03854.14 EGC37704.1 - 0.55 9.9 4.2 1.4 8.6 4.2 1.8 1 0 0 1 1 1 0 P-11 zinc finger Rad50_zn_hook PF04423.14 EGC37704.1 - 1.7 8.5 5.6 2.2 8.2 0.1 3.3 3 0 0 3 3 3 0 Rad50 zinc hook motif Clathrin PF00637.20 EGC37705.1 - 4e-25 88.4 6.5 4e-25 88.4 6.5 2.8 2 1 0 2 2 2 1 Region in Clathrin and VPS Vps39_2 PF10367.9 EGC37705.1 - 1.2e-07 32.2 0.4 3.9e-07 30.5 0.4 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.32 EGC37705.1 - 0.0032 18.3 0.4 0.034 15.0 0.1 2.9 3 0 0 3 3 2 1 WD domain, G-beta repeat zf-ANAPC11 PF12861.7 EGC37705.1 - 0.013 15.5 0.4 0.13 12.4 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC37705.1 - 0.031 14.2 6.2 0.16 11.9 6.2 2.3 1 1 0 1 1 1 0 zinc-RING finger domain zf-C3H2C3 PF17122.5 EGC37705.1 - 0.044 13.8 1.0 0.16 12.0 1.0 2.0 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EGC37705.1 - 0.057 13.6 2.6 0.43 10.8 0.0 2.8 3 0 0 3 3 2 0 FANCL C-terminal domain ANAPC4_WD40 PF12894.7 EGC37705.1 - 0.1 12.9 0.0 1.5 9.1 0.0 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 4 WD40 domain zf-rbx1 PF12678.7 EGC37705.1 - 0.12 12.7 1.8 0.22 11.8 0.2 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger domain Helicase_PWI PF18149.1 EGC37705.1 - 0.12 12.5 3.3 0.98 9.6 0.3 3.2 2 1 0 2 2 2 0 N-terminal helicase PWI domain zf-RING_11 PF17123.5 EGC37705.1 - 0.14 11.9 6.5 0.078 12.7 1.9 2.7 2 0 0 2 2 2 0 RING-like zinc finger CDC45 PF02724.14 EGC37705.1 - 0.17 10.1 12.1 0.27 9.5 12.1 1.2 1 0 0 1 1 1 0 CDC45-like protein Mpp10 PF04006.12 EGC37705.1 - 0.19 10.1 22.2 0.32 9.4 22.2 1.2 1 0 0 1 1 1 0 Mpp10 protein zf-RING_UBOX PF13445.6 EGC37705.1 - 0.38 10.8 6.7 0.059 13.4 1.0 2.3 2 0 0 2 2 2 0 RING-type zinc-finger Vps39_1 PF10366.9 EGC37705.1 - 0.55 10.5 8.0 0.12 12.7 2.6 2.6 2 1 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 Oscp1 PF10188.9 EGC37705.1 - 0.56 10.3 2.7 1.3 9.1 0.1 2.5 3 0 0 3 3 3 0 Organic solute transport protein 1 TFIIF_alpha PF05793.12 EGC37705.1 - 0.82 8.2 22.8 1.3 7.5 22.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FYDLN_acid PF09538.10 EGC37705.1 - 3.1 8.5 15.6 12 6.7 15.6 2.0 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) zf-RING_2 PF13639.6 EGC37705.1 - 3.5 8.1 10.6 0.19 12.1 0.6 3.3 3 0 0 3 3 3 0 Ring finger domain Presenilin PF01080.17 EGC37705.1 - 5.5 5.6 8.5 9.6 4.9 8.5 1.3 1 0 0 1 1 1 0 Presenilin Pox_Ag35 PF03286.14 EGC37705.1 - 9.2 6.0 12.3 19 5.0 12.3 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein SapB_2 PF03489.17 EGC37706.1 - 6.2e-36 122.2 18.1 7.6e-13 48.3 2.1 4.0 3 0 0 3 3 3 3 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC37706.1 - 5.7e-34 115.7 17.7 4.5e-12 45.7 0.4 4.4 4 0 0 4 4 4 3 Saposin-like type B, region 1 DUF4359 PF14271.6 EGC37706.1 - 0.0093 16.7 1.7 15 6.5 0.2 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF4359) CCDC24 PF15669.5 EGC37706.1 - 0.038 13.8 0.2 0.069 13.0 0.2 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family BLM10_mid PF16507.5 EGC37706.1 - 0.083 11.5 1.0 0.15 10.7 0.5 1.5 1 1 1 2 2 2 0 Proteasome-substrate-size regulator, mid region DNA_pol_phi PF04931.13 EGC37706.1 - 0.18 9.8 0.1 0.26 9.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase phi Cation_ATPase_C PF00689.21 EGC37707.1 - 1e-43 149.2 4.2 1e-43 149.2 4.2 2.6 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus E1-E2_ATPase PF00122.20 EGC37707.1 - 1.2e-37 129.2 1.3 1.2e-37 129.2 1.3 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase PF13246.6 EGC37707.1 - 1.6e-19 69.8 0.0 2.9e-19 68.9 0.0 1.4 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC37707.1 - 2.6e-15 57.3 3.8 2.3e-14 54.2 3.8 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC37707.1 - 1.2e-12 47.3 0.0 3e-12 46.0 0.0 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.12 EGC37707.1 - 0.00047 20.0 0.2 0.084 12.6 0.2 2.4 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Wzy_C PF04932.15 EGC37707.1 - 0.0017 18.0 5.3 0.46 10.1 0.1 3.1 4 0 0 4 4 4 2 O-Antigen ligase NAD_synthase PF02540.17 EGC37707.1 - 0.051 12.7 0.0 0.096 11.8 0.0 1.3 1 0 0 1 1 1 0 NAD synthase DUF1980 PF09323.10 EGC37707.1 - 0.064 13.2 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3792 PF12670.7 EGC37707.1 - 0.16 12.2 0.1 0.16 12.2 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3792) DUF1772 PF08592.11 EGC37707.1 - 0.47 10.8 3.8 0.55 10.5 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF1772) CLP1_P PF16575.5 EGC37708.1 - 3.1e-37 128.2 0.1 3.1e-37 128.2 0.1 2.3 3 0 0 3 3 3 1 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_14 PF13173.6 EGC37708.1 - 0.0099 15.9 0.0 0.047 13.7 0.0 2.2 1 0 0 1 1 1 1 AAA domain SWI-SNF_Ssr4 PF08549.10 EGC37709.1 - 0.22 10.1 5.3 0.26 9.9 5.3 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) SSP160 PF06933.11 EGC37709.1 - 0.59 8.3 14.8 0.6 8.2 14.8 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Macoilin PF09726.9 EGC37709.1 - 6.8 5.1 14.2 7.6 5.0 14.2 1.0 1 0 0 1 1 1 0 Macoilin family DUF1712 PF08217.11 EGC37710.1 - 2.5e-76 257.5 19.4 1.2e-67 228.9 11.0 2.6 1 1 1 2 2 2 2 Fungal domain of unknown function (DUF1712) DUF3466 PF11949.8 EGC37710.1 - 0.08 11.5 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3466) Gelsolin PF00626.22 EGC37711.1 - 2.5e-50 168.3 1.0 5.5e-12 45.4 0.0 5.5 5 0 0 5 5 5 5 Gelsolin repeat PH PF00169.29 EGC37711.1 - 1.1e-16 61.2 4.1 6.4e-07 29.8 0.1 4.2 3 0 0 3 3 3 3 PH domain VHP PF02209.19 EGC37711.1 - 1.9e-14 53.4 2.0 4.4e-14 52.2 2.0 1.7 1 0 0 1 1 1 1 Villin headpiece domain WD40_4 PF16300.5 EGC37711.1 - 5.1e-13 48.7 0.2 1.1e-12 47.7 0.2 1.6 1 0 0 1 1 1 1 Type of WD40 repeat WD40 PF00400.32 EGC37711.1 - 5.8e-10 39.6 3.4 1.7e-05 25.5 0.3 4.4 3 0 0 3 3 3 2 WD domain, G-beta repeat DUF1899 PF08953.11 EGC37711.1 - 8.2e-09 35.2 0.1 2.3e-08 33.8 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) PH_6 PF15406.6 EGC37711.1 - 0.0042 17.3 0.1 19 5.6 0.0 4.0 3 0 0 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 EGC37711.1 - 2.4 8.6 6.3 19 5.7 0.2 4.2 3 1 1 4 4 4 0 Pleckstrin homology domain HEAT PF02985.22 EGC37712.1 - 0.033 14.4 0.0 5.1 7.6 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat ORC_WH_C PF18137.1 EGC37712.1 - 0.036 14.1 5.2 0.73 9.9 0.0 4.0 3 2 0 3 3 3 0 Origin recognition complex winged helix C-terminal DUF4349 PF14257.6 EGC37712.1 - 0.23 10.9 0.0 0.23 10.9 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4349) zf_CopZ PF18423.1 EGC37713.1 - 0.022 14.7 1.1 0.049 13.6 1.1 1.6 1 0 0 1 1 1 0 Zinc binding domain UPF0697 PF15117.6 EGC37713.1 - 0.12 12.4 0.0 0.22 11.6 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 zn-ribbon_14 PF16503.5 EGC37713.1 - 0.56 9.8 0.1 0.56 9.8 0.1 3.6 3 0 0 3 3 3 0 Zinc-ribbon Orf78 PF06024.12 EGC37714.1 - 0.0089 16.3 0.4 0.0089 16.3 0.4 1.9 2 0 0 2 2 2 1 Orf78 (ac78) Phage_CI_C PF16452.5 EGC37714.1 - 0.1 12.9 1.2 0.73 10.2 0.0 2.5 3 0 0 3 3 3 0 Bacteriophage CI repressor C-terminal domain RRM_1 PF00076.22 EGC37715.1 - 1.4e-15 56.9 0.0 2.2e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.23 EGC37715.1 - 5.6e-05 23.0 1.6 0.00012 22.0 1.6 1.6 1 0 0 1 1 1 1 Zinc knuckle PRP38_assoc PF12871.7 EGC37715.1 - 6.2e-05 23.5 51.6 6.2e-05 23.5 51.6 2.6 1 1 1 2 2 2 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term RRM_3 PF08777.11 EGC37715.1 - 0.0004 20.4 0.1 0.00093 19.2 0.1 1.6 1 0 0 1 1 1 1 RNA binding motif zf-CCHC_2 PF13696.6 EGC37715.1 - 0.012 15.4 2.6 0.018 14.8 2.6 1.3 1 0 0 1 1 1 0 Zinc knuckle RRM_7 PF16367.5 EGC37715.1 - 0.023 14.8 0.0 1.9 8.6 0.0 2.3 1 1 0 1 1 1 0 RNA recognition motif Apt1 PF10351.9 EGC37715.1 - 2.1 7.1 14.8 2.4 6.9 14.8 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain CDC45 PF02724.14 EGC37715.1 - 2.1 6.5 17.6 2.5 6.3 17.6 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF4614 PF15391.6 EGC37715.1 - 2.2 8.2 11.2 3.9 7.4 11.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) NPR3 PF03666.13 EGC37715.1 - 5.5 5.7 11.9 6.9 5.3 11.9 1.3 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 Presenilin PF01080.17 EGC37715.1 - 5.8 5.6 8.5 6.2 5.5 8.5 1.2 1 0 0 1 1 1 0 Presenilin zf-CCHC PF00098.23 EGC37716.1 - 9.7e-09 34.9 1.5 1.9e-08 34.0 1.5 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGC37716.1 - 0.029 14.1 1.4 0.052 13.3 1.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_2 PF13696.6 EGC37716.1 - 0.036 13.9 0.8 0.062 13.1 0.8 1.4 1 0 0 1 1 1 0 Zinc knuckle DBR1 PF05011.13 EGC37717.1 - 1.4e-15 58.0 1.3 1.4e-15 58.0 1.3 2.1 2 0 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.28 EGC37717.1 - 1.4e-07 32.2 0.2 3.4e-07 31.0 0.2 1.7 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC37717.1 - 0.00047 20.4 0.0 0.011 15.9 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_2 PF00891.18 EGC37718.1 - 7.8e-46 156.0 0.0 1.1e-45 155.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Methyltransf_25 PF13649.6 EGC37718.1 - 0.00023 21.8 0.0 0.00067 20.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC37718.1 - 0.00088 20.0 0.0 0.0017 19.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC37718.1 - 0.001 19.7 0.0 0.0031 18.1 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC37718.1 - 0.0013 18.1 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Ldh_1_C PF02866.18 EGC37719.1 - 7.7e-37 126.8 0.0 1.8e-36 125.6 0.0 1.6 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGC37719.1 - 1.4e-34 119.2 0.8 2.2e-34 118.6 0.8 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RNase_PH PF01138.21 EGC37720.1 - 1.2e-22 80.9 0.0 4.9e-22 78.8 0.0 1.9 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGC37720.1 - 2.5e-13 49.9 0.2 4.7e-13 49.0 0.2 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 PG_isomerase_N PF18353.1 EGC37720.1 - 0.039 14.4 0.0 0.3 11.5 0.0 2.1 1 1 1 2 2 2 0 Phosphoglucose isomerase N-terminal domain Actin PF00022.19 EGC37721.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin CBS PF00571.28 EGC37722.1 - 1.4e-22 79.8 0.5 4.8e-06 26.9 0.0 4.3 4 0 0 4 4 4 4 CBS domain GARS_N PF02844.15 EGC37722.1 - 0.079 13.8 0.0 0.18 12.6 0.0 1.6 1 0 0 1 1 1 0 Phosphoribosylglycinamide synthetase, N domain VKOR PF07884.14 EGC37723.1 - 7.6e-17 61.7 14.6 1.2e-16 61.0 14.6 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family COPI_assoc PF08507.10 EGC37723.1 - 0.0055 16.8 8.0 0.0055 16.8 8.0 2.0 1 1 1 2 2 2 1 COPI associated protein Mito_carr PF00153.27 EGC37724.1 - 4.5e-64 212.4 2.6 1.4e-22 79.4 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein HMD PF03201.16 EGC37724.1 - 0.072 13.3 0.0 2.1 8.6 0.0 2.3 2 0 0 2 2 2 0 H2-forming N5,N10-methylene-tetrahydromethanopterin dehydrogenase SOG2 PF10428.9 EGC37725.1 - 2.1 7.5 29.1 3.2 6.9 29.1 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein U1snRNP70_N PF12220.8 EGC37725.1 - 3.3 8.4 8.9 1.1 10.0 1.3 3.2 3 0 0 3 3 3 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF4834 PF16118.5 EGC37726.1 - 0.075 14.0 0.1 0.075 14.0 0.1 4.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4834) Tmemb_9 PF05434.11 EGC37726.1 - 0.79 9.6 0.0 0.79 9.6 0.0 2.4 2 1 0 2 2 2 0 TMEM9 Tetraspanin PF00335.20 EGC37726.1 - 1.4 8.6 3.5 3.6 7.2 3.5 1.7 1 1 0 1 1 1 0 Tetraspanin family CFIA_Pcf11 PF11526.8 EGC37727.1 - 0.26 11.8 10.4 0.45 11.0 10.4 1.5 1 1 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 PTS_2-RNA PF01885.16 EGC37728.1 - 1e-66 224.5 0.3 1.2e-66 224.2 0.3 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HECT PF00632.25 EGC37729.1 - 6.2e-59 200.0 0.8 2.8e-58 197.8 0.1 2.6 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.28 EGC37729.1 - 7.7e-21 74.4 1.2 2.8e-20 72.6 1.2 2.1 1 0 0 1 1 1 1 SPRY domain PH PF00169.29 EGC37729.1 - 1.5e-17 64.0 0.1 1.1e-16 61.2 0.1 2.8 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGC37729.1 - 1.5e-07 31.8 3.6 1.7e-07 31.6 0.3 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain CUB PF00431.20 EGC37729.1 - 0.00023 21.5 0.1 0.04 14.2 0.0 3.9 4 0 0 4 4 4 1 CUB domain PH_11 PF15413.6 EGC37729.1 - 0.098 13.1 6.5 0.035 14.5 0.2 3.9 2 0 0 2 2 2 0 Pleckstrin homology domain SNF2_N PF00176.23 EGC37730.1 - 3.5e-73 246.3 0.3 7.3e-73 245.3 0.3 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.31 EGC37730.1 - 5.4e-08 33.2 1.4 1.4e-07 31.9 0.1 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.6 EGC37730.1 - 6.2e-06 26.5 10.8 6.2e-06 26.5 10.8 3.5 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC37730.1 - 1.5e-05 24.8 10.3 1.5e-05 24.8 10.3 2.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC37730.1 - 7.2e-05 22.7 5.2 7.2e-05 22.7 5.2 3.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC37730.1 - 0.00011 22.0 10.9 0.00011 22.0 10.9 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC37730.1 - 0.001 18.8 11.3 0.001 18.8 11.3 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37730.1 - 0.0015 18.4 9.5 0.0015 18.4 9.5 3.0 2 1 1 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.8 EGC37730.1 - 0.79 9.6 7.6 3 7.7 7.6 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SKA2 PF16740.5 EGC37731.1 - 0.004 16.9 1.3 0.004 16.9 1.3 2.2 1 1 1 2 2 2 1 Spindle and kinetochore-associated protein 2 YgaB PF14182.6 EGC37731.1 - 0.39 11.1 9.6 1.1 9.7 1.5 3.0 1 1 2 3 3 3 0 YgaB-like protein PRKG1_interact PF15898.5 EGC37731.1 - 0.57 11.1 8.5 4.7 8.2 0.6 2.4 2 0 0 2 2 2 0 cGMP-dependent protein kinase interacting domain IZUMO PF15005.6 EGC37731.1 - 0.68 10.4 8.4 0.11 13.0 2.1 2.2 1 1 1 2 2 2 0 Izumo sperm-egg fusion, Ig domain-associated Vac_Fusion PF02346.16 EGC37731.1 - 1.7 8.4 8.3 7.3 6.3 0.0 3.7 2 1 2 4 4 4 0 Chordopoxvirus multifunctional envelope protein A27 Abhydrolase_1 PF00561.20 EGC37732.1 - 1.8e-06 27.8 0.0 3.6e-06 26.8 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC37732.1 - 2.6e-05 24.9 0.0 3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.12 EGC37732.1 - 0.017 13.9 0.0 0.029 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Hydrolase_4 PF12146.8 EGC37732.1 - 0.036 13.3 0.0 0.046 13.0 0.0 1.2 1 0 0 1 1 1 0 Serine aminopeptidase, S33 DJ-1_PfpI PF01965.24 EGC37733.1 - 1.8e-44 151.5 0.0 2e-44 151.3 0.0 1.0 1 0 0 1 1 1 1 DJ-1/PfpI family ThiJ_like PF17124.5 EGC37733.1 - 0.00015 21.6 0.1 0.00051 19.8 0.1 2.0 1 1 0 1 1 1 1 ThiJ/PfpI family-like GATase PF00117.28 EGC37733.1 - 0.0032 17.3 0.0 0.0044 16.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.14 EGC37733.1 - 0.013 15.1 0.0 0.02 14.5 0.0 1.2 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.13 EGC37733.1 - 0.055 13.2 0.0 0.13 12.0 0.0 1.7 1 1 0 1 1 1 0 Peptidase C26 Catalase_C PF18011.1 EGC37733.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 C-terminal domain found in long catalases ELFV_dehydrog PF00208.21 EGC37734.1 - 5.8e-55 186.7 0.0 8.8e-55 186.1 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.12 EGC37734.1 - 1.8e-24 85.5 0.1 6.7e-15 53.8 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.18 EGC37734.1 - 0.035 14.0 0.0 0.3 11.0 0.0 2.2 2 0 0 2 2 2 0 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Thy1 PF02511.15 EGC37735.1 - 8.6e-50 169.2 0.1 1.2e-49 168.7 0.1 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein CMS1 PF14617.6 EGC37736.1 - 6.5e-11 42.0 20.4 1.1e-09 38.1 20.0 2.8 1 1 1 2 2 2 1 U3-containing 90S pre-ribosomal complex subunit Menin PF05053.13 EGC37736.1 - 4.7 5.5 8.8 6.6 5.0 8.8 1.1 1 0 0 1 1 1 0 Menin Hid1 PF12722.7 EGC37736.1 - 5.5 5.0 8.3 7.5 4.5 8.3 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RabGAP-TBC PF00566.18 EGC37738.1 - 6.9e-22 78.2 13.7 1.1e-13 51.4 3.3 9.3 5 3 2 7 7 7 2 Rab-GTPase-TBC domain ZapB PF06005.12 EGC37738.1 - 0.00091 19.6 2.5 0.00091 19.6 2.5 3.3 2 0 0 2 2 2 1 Cell division protein ZapB UME PF08064.13 EGC37738.1 - 0.6 10.1 2.8 0.74 9.8 0.0 2.6 3 0 0 3 3 3 0 UME (NUC010) domain DUF4337 PF14235.6 EGC37738.1 - 5.5 7.1 5.5 2.2 8.4 1.4 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) SPR1 PF15356.6 EGC37740.1 - 0.06 13.9 2.9 0.089 13.3 2.9 1.3 1 0 0 1 1 1 0 Psoriasis susceptibility locus 2 Asp-B-Hydro_N PF05279.11 EGC37740.1 - 1.1 9.2 20.7 1.5 8.9 20.7 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ank_3 PF13606.6 EGC37741.1 - 8.2e-05 22.7 2.2 1.5 9.6 0.0 5.1 4 0 0 4 4 4 2 Ankyrin repeat Ank_2 PF12796.7 EGC37741.1 - 0.00091 19.8 8.7 0.004 17.7 0.1 4.1 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) AAA PF00004.29 EGC37742.1 - 6.3e-37 127.0 0.0 6.3e-37 127.0 0.0 2.2 3 1 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.18 EGC37742.1 - 9.6e-11 41.6 3.4 2.7e-10 40.2 3.4 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGC37742.1 - 1.9e-08 34.0 0.0 4.2e-08 32.9 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGC37742.1 - 1.6e-07 31.2 0.0 9.5e-07 28.7 0.0 2.3 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain AAA_2 PF07724.14 EGC37742.1 - 6.4e-05 23.1 0.1 0.00032 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.12 EGC37742.1 - 6.7e-05 22.7 0.0 0.00016 21.4 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC37742.1 - 0.00017 21.9 3.3 0.0012 19.2 1.1 3.4 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.14 EGC37742.1 - 0.00039 20.4 0.1 0.0035 17.3 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.13 EGC37742.1 - 0.00052 19.3 0.0 0.0013 18.1 0.0 1.6 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_16 PF13191.6 EGC37742.1 - 0.00091 19.7 1.1 0.0064 16.9 0.2 2.7 2 1 0 2 2 2 1 AAA ATPase domain DUF815 PF05673.13 EGC37742.1 - 0.0026 17.0 0.0 0.0067 15.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TniB PF05621.11 EGC37742.1 - 0.0031 17.0 0.4 3.9 6.8 0.0 2.9 2 1 0 3 3 3 2 Bacterial TniB protein AAA_14 PF13173.6 EGC37742.1 - 0.0032 17.5 1.0 0.036 14.1 0.0 3.0 3 0 0 3 3 3 1 AAA domain IstB_IS21 PF01695.17 EGC37742.1 - 0.0043 16.8 0.0 0.0092 15.7 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGC37742.1 - 0.0045 16.4 0.1 0.011 15.1 0.1 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGC37742.1 - 0.013 15.3 0.0 0.045 13.5 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC37742.1 - 0.038 14.1 0.0 0.15 12.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain SUIM_assoc PF16619.5 EGC37742.1 - 0.058 13.5 13.5 0.22 11.6 5.9 2.6 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 AAA_18 PF13238.6 EGC37742.1 - 0.089 13.3 0.4 0.41 11.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.6 EGC37742.1 - 0.1 12.2 0.1 1.3 8.6 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_17 PF13207.6 EGC37742.1 - 0.1 13.0 0.4 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain DUF3288 PF11691.8 EGC37742.1 - 0.15 12.1 2.8 1.8 8.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3288) ATPase PF06745.13 EGC37742.1 - 0.24 10.7 2.1 9.4 5.5 0.1 2.9 2 1 1 3 3 2 0 KaiC Ferredoxin_N PF16947.5 EGC37743.1 - 0.093 12.9 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of 4Fe-4S ferredoxin iron-sulfur binding GcrA PF07750.11 EGC37744.1 - 0.013 15.9 2.9 0.017 15.5 2.9 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator Rho_N PF07498.12 EGC37744.1 - 0.035 14.1 0.0 0.075 13.0 0.0 1.7 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain DRE2_N PF16803.5 EGC37744.1 - 0.059 13.6 0.1 0.065 13.5 0.1 1.1 1 0 0 1 1 1 0 Fe-S cluster assembly protein DRE2 N-terminus DUF4820 PF16091.5 EGC37744.1 - 0.22 10.9 2.3 0.23 10.8 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) adh_short PF00106.25 EGC37745.1 - 1.5e-15 57.2 0.0 1.9e-09 37.2 0.0 2.3 2 0 0 2 2 2 2 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37745.1 - 3.8e-09 36.5 0.0 0.00067 19.3 0.0 2.2 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC37745.1 - 0.00045 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Macoilin PF09726.9 EGC37745.1 - 0.24 9.9 19.8 0.41 9.2 19.8 1.4 1 0 0 1 1 1 0 Macoilin family HALZ PF02183.18 EGC37745.1 - 0.26 11.5 11.7 2.1 8.6 2.6 2.9 2 0 0 2 2 2 0 Homeobox associated leucine zipper FAE1_CUT1_RppA PF08392.12 EGC37746.1 - 6e-126 419.6 0.0 7.7e-126 419.3 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.10 EGC37746.1 - 1.2e-10 41.4 0.0 1.8e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.15 EGC37746.1 - 4.3e-10 39.8 0.0 8.8e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.19 EGC37746.1 - 0.00022 20.7 0.1 0.00074 19.0 0.0 1.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain BPD_transp_1 PF00528.22 EGC37746.1 - 0.0084 15.9 0.8 0.013 15.2 0.8 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ACP_syn_III PF08545.10 EGC37746.1 - 0.018 14.9 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.25 EGC37748.1 - 3.1e-39 134.5 0.0 3.7e-39 134.2 0.0 1.0 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37748.1 - 4.8e-27 95.0 0.0 9.6e-27 94.0 0.0 1.5 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.10 EGC37748.1 - 2.5e-08 33.6 0.0 5e-08 32.7 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGC37748.1 - 8.6e-08 32.3 0.0 1.1e-07 31.9 0.0 1.1 1 0 0 1 1 1 1 KR domain 3HCDH_N PF02737.18 EGC37748.1 - 0.0036 17.2 0.0 0.006 16.5 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGC37748.1 - 0.013 16.0 0.1 0.033 14.8 0.0 1.8 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.15 EGC37748.1 - 0.014 15.5 0.0 0.031 14.5 0.0 1.8 1 1 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Adenylsucc_synt PF00709.21 EGC37748.1 - 0.034 13.1 0.0 0.048 12.6 0.0 1.3 1 1 0 1 1 1 0 Adenylosuccinate synthetase Shikimate_DH PF01488.20 EGC37748.1 - 0.077 13.1 0.0 0.14 12.2 0.0 1.4 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase YopE PF03545.13 EGC37748.1 - 0.1 12.7 0.1 0.2 11.8 0.1 1.4 1 0 0 1 1 1 0 Yersinia virulence determinant (YopE) THF_DHG_CYH_C PF02882.19 EGC37748.1 - 0.19 11.1 0.0 0.32 10.3 0.0 1.3 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Pkinase PF00069.25 EGC37749.1 - 3.2e-52 177.5 0.3 3.2e-52 177.5 0.3 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37749.1 - 3.4e-21 75.7 0.0 8.1e-21 74.5 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC37749.1 - 0.018 14.9 0.0 0.018 14.9 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family MFS_5 PF05631.14 EGC37751.1 - 8.3e-104 347.3 16.9 1e-103 347.0 16.9 1.1 1 0 0 1 1 1 1 Sugar-tranasporters, 12 TM MFS_1 PF07690.16 EGC37751.1 - 9e-20 70.9 32.2 1.8e-19 69.9 32.2 1.6 1 1 0 1 1 1 1 Major Facilitator Superfamily DUF4044 PF13253.6 EGC37751.1 - 0.046 13.2 1.2 0.18 11.4 1.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Cation_efflux PF01545.21 EGC37752.1 - 1.4e-49 168.5 7.7 2e-49 168.1 7.7 1.2 1 0 0 1 1 1 1 Cation efflux family Zip PF02535.22 EGC37752.1 - 4e-05 23.0 40.2 0.0045 16.2 19.5 2.4 2 1 0 2 2 2 2 ZIP Zinc transporter Sec62 PF03839.16 EGC37752.1 - 0.0054 16.3 0.6 0.11 12.0 0.0 2.5 2 0 0 2 2 2 1 Translocation protein Sec62 PBP1_TM PF14812.6 EGC37752.1 - 0.025 15.0 0.4 0.025 15.0 0.4 3.2 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF5412 PF17428.2 EGC37752.1 - 0.2 11.5 3.7 0.66 9.8 3.7 1.9 1 0 0 1 1 1 0 Family of unknown function (DUF5412) DUF4604 PF15377.6 EGC37752.1 - 1.9 8.9 18.4 1.1 9.6 10.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4604) Pribosyltran_N PF13793.6 EGC37753.1 - 4.4e-43 145.9 0.2 4e-42 142.8 0.0 2.3 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.6 EGC37753.1 - 3.1e-30 105.6 1.2 3.1e-29 102.3 0.2 2.4 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.27 EGC37753.1 - 5.5e-07 29.2 0.8 2.1e-06 27.4 0.8 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Mob1_phocein PF03637.17 EGC37754.1 - 1.6e-59 200.7 0.1 1.8e-59 200.5 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family IBN_N PF03810.19 EGC37755.1 - 0.00054 19.8 0.3 0.00054 19.8 0.3 2.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain VPR PF00522.18 EGC37755.1 - 0.15 12.1 0.0 0.58 10.2 0.0 2.0 1 0 0 1 1 1 0 VPR/VPX protein Peptidase_M1 PF01433.20 EGC37760.1 - 1.2e-77 260.4 1.4 1.2e-77 260.4 1.4 1.6 2 0 0 2 2 2 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGC37760.1 - 4.9e-68 230.0 0.0 1.2e-67 228.8 0.0 1.6 2 0 0 2 2 2 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGC37760.1 - 2.8e-53 180.9 1.6 4.6e-53 180.2 1.6 1.4 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain Peptidase_M48 PF01435.18 EGC37760.1 - 0.012 15.4 0.0 0.11 12.3 0.0 2.2 2 0 0 2 2 2 0 Peptidase family M48 tRNA_anti-codon PF01336.25 EGC37761.1 - 0.041 13.9 0.0 0.063 13.3 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CDC24_OB3 PF17244.2 EGC37761.1 - 0.2 11.3 0.0 0.22 11.2 0.0 1.1 1 0 0 1 1 1 0 Cell division control protein 24, OB domain 3 RelA_SpoT PF04607.17 EGC37762.1 - 9.9e-07 29.1 0.3 2.7e-06 27.7 0.3 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins DUF5595 PF18077.1 EGC37762.1 - 0.038 14.1 1.6 5.5 7.1 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF5595) DUF2310 PF10071.9 EGC37762.1 - 0.041 13.1 0.3 0.2 10.9 0.0 2.1 2 1 0 2 2 2 0 Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310) CDC4_D PF16856.5 EGC37762.1 - 0.078 12.9 2.2 0.17 11.8 0.4 2.5 2 0 0 2 2 2 0 Cell division control protein 4 dimerisation domain WD40 PF00400.32 EGC37763.1 - 5.8e-16 58.6 24.2 4.6e-07 30.4 0.2 8.7 8 1 0 8 8 8 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC37763.1 - 1e-07 32.2 9.4 0.11 12.9 0.5 6.4 2 2 3 6 6 6 4 Anaphase-promoting complex subunit 4 WD40 domain Beta_propel PF09826.9 EGC37763.1 - 0.027 13.3 0.5 0.068 12.0 0.1 1.9 2 0 0 2 2 2 0 Beta propeller domain adh_short PF00106.25 EGC37765.1 - 1.3e-06 28.1 0.0 2.2e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC37765.1 - 0.0036 16.9 0.0 0.0058 16.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC37765.1 - 0.22 11.4 0.0 0.37 10.7 0.0 1.3 1 0 0 1 1 1 0 KR domain Aldedh PF00171.22 EGC37766.1 - 6.9e-164 545.7 0.0 7.8e-164 545.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.11 EGC37766.1 - 0.099 12.1 0.1 0.54 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TPR_1 PF00515.28 EGC37767.1 - 1.1e-08 34.5 14.7 1.5e-05 24.6 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.12 EGC37767.1 - 7.1e-07 29.7 13.2 0.0042 17.7 0.1 5.3 5 0 0 5 5 5 2 Sel1 repeat TPR_2 PF07719.17 EGC37767.1 - 2.3e-06 27.3 15.2 0.00034 20.5 0.1 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC37767.1 - 8.2e-05 22.8 5.0 0.4 11.0 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC37767.1 - 0.00017 21.7 1.1 0.68 10.4 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.6 EGC37767.1 - 0.00063 20.4 1.3 0.025 15.4 0.0 3.4 4 0 0 4 4 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC37767.1 - 0.00066 19.3 8.8 0.13 12.0 0.0 4.7 3 2 2 5 5 5 2 TPR repeat TPR_7 PF13176.6 EGC37767.1 - 0.0042 17.0 7.3 1.1 9.4 0.2 5.3 5 3 3 8 8 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37767.1 - 0.0055 16.8 0.1 0.0055 16.8 0.1 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC37767.1 - 0.018 15.1 0.7 0.1 12.7 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_16 PF13432.6 EGC37767.1 - 0.07 13.8 9.0 22 5.8 0.1 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat MIT PF04212.18 EGC37767.1 - 0.13 12.3 4.8 13 5.9 0.1 4.8 6 0 0 6 6 6 0 MIT (microtubule interacting and transport) domain TPR_6 PF13174.6 EGC37767.1 - 3.6 8.4 8.2 6.3 7.7 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat CH PF00307.31 EGC37770.1 - 1.3e-41 141.2 12.3 1e-14 54.6 0.3 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain UTP15_C PF09384.10 EGC37771.1 - 1.1e-25 90.1 1.4 1.6e-25 89.5 1.4 1.3 1 0 0 1 1 1 1 UTP15 C terminal WD40 PF00400.32 EGC37771.1 - 4.8e-16 58.9 5.4 0.00044 21.0 0.2 5.5 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40_like PF17005.5 EGC37771.1 - 1.6e-07 31.0 0.3 0.00013 21.4 0.1 2.4 1 1 1 2 2 2 2 WD40-like domain ANAPC4_WD40 PF12894.7 EGC37771.1 - 1.3e-06 28.7 0.2 0.0088 16.3 0.0 4.5 1 1 3 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain p450 PF00067.22 EGC37771.1 - 0.014 14.2 1.4 0.021 13.6 1.4 1.3 1 0 0 1 1 1 0 Cytochrome P450 Utp13 PF08625.11 EGC37771.1 - 0.034 14.0 1.1 0.071 13.0 1.1 1.5 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain Terminase_3 PF04466.13 EGC37771.1 - 0.059 12.9 7.5 1.3 8.5 0.2 3.6 3 1 0 3 3 3 0 Phage terminase large subunit Ntox50 PF15542.6 EGC37771.1 - 0.86 10.4 4.8 1.6 9.6 0.1 3.3 3 0 0 3 3 3 0 Bacterial toxin 50 ABC_tran PF00005.27 EGC37772.1 - 0.00018 22.1 2.1 0.00018 22.1 2.1 3.0 4 0 0 4 4 4 1 ABC transporter Roc PF08477.13 EGC37772.1 - 0.0054 17.0 0.5 0.11 12.7 0.3 3.0 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EGC37772.1 - 0.015 15.3 0.1 0.057 13.4 0.1 2.1 1 0 0 1 1 1 0 AAA domain Dynamin_N PF00350.23 EGC37772.1 - 0.019 15.0 3.6 0.019 15.0 3.6 3.0 2 1 1 3 3 3 0 Dynamin family ATPase_2 PF01637.18 EGC37772.1 - 0.028 14.4 0.6 0.062 13.2 0.1 1.8 2 0 0 2 2 2 0 ATPase domain predominantly from Archaea AAA_28 PF13521.6 EGC37772.1 - 0.036 14.3 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGC37772.1 - 0.087 12.9 2.2 0.32 11.1 2.2 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase TFIIA PF03153.13 EGC37772.1 - 1.3 8.9 37.1 1 9.3 18.0 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TIG PF01833.24 EGC37773.1 - 3.9e-06 26.8 13.7 2.1e-05 24.5 0.8 3.3 2 0 0 2 2 2 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC37773.1 - 0.0053 16.9 22.2 0.042 14.0 5.9 2.7 2 0 0 2 2 2 2 Laminin EGF domain DUF4279 PF14106.6 EGC37773.1 - 0.057 13.6 0.1 0.15 12.3 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4279) LRR_8 PF13855.6 EGC37773.1 - 0.64 9.8 8.8 1.6 8.6 0.4 5.1 5 0 0 5 5 5 0 Leucine rich repeat DUF3642 PF12182.8 EGC37773.1 - 1.8 8.9 6.3 2.4 8.5 0.1 3.6 3 0 0 3 3 3 0 Bacterial lipoprotein WD40 PF00400.32 EGC37774.1 - 1.1e-13 51.4 1.0 2.7e-06 28.0 0.0 5.1 6 0 0 6 6 6 2 WD domain, G-beta repeat WD40_like PF17005.5 EGC37774.1 - 3.3e-07 30.0 9.3 0.0029 17.0 3.5 2.6 1 1 1 2 2 2 2 WD40-like domain Coatomer_WDAD PF04053.14 EGC37774.1 - 5.5e-06 25.7 2.5 5.5e-06 25.7 2.5 1.6 2 0 0 2 2 2 1 Coatomer WD associated region ANAPC4_WD40 PF12894.7 EGC37774.1 - 5.4e-05 23.4 1.3 0.66 10.3 0.1 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC37774.1 - 0.00016 20.5 1.3 0.064 11.9 0.1 3.1 1 1 2 3 3 3 2 Nucleoporin Nup120/160 WD40_3 PF15911.5 EGC37774.1 - 0.073 13.1 0.4 0.38 10.8 0.1 2.4 2 0 0 2 2 2 0 WD domain, G-beta repeat Arf PF00025.21 EGC37775.1 - 3.3e-48 163.5 0.0 4.3e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGC37775.1 - 8.5e-17 61.3 1.7 2.1e-12 46.9 0.1 2.6 2 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGC37775.1 - 6.2e-12 45.8 0.0 1.2e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Ras PF00071.22 EGC37775.1 - 1.7e-10 40.7 0.0 2.1e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.10 EGC37775.1 - 1.3e-08 34.5 0.0 1.7e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC37775.1 - 1.9e-08 33.9 0.0 2.3e-08 33.7 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC37775.1 - 3.8e-06 27.0 0.1 6.6e-05 23.0 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_22 PF13401.6 EGC37775.1 - 0.00077 19.7 0.0 0.0016 18.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC37775.1 - 0.0026 17.7 0.1 2.3 8.1 0.0 2.3 1 1 0 2 2 2 2 RsgA GTPase AAA_23 PF13476.6 EGC37775.1 - 0.0029 18.1 0.8 0.0043 17.6 0.8 1.5 1 1 0 1 1 1 1 AAA domain GTP_EFTU PF00009.27 EGC37775.1 - 0.0035 16.9 0.0 0.43 10.1 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain NB-ARC PF00931.22 EGC37775.1 - 0.0054 16.0 0.0 0.0097 15.1 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain cobW PF02492.19 EGC37775.1 - 0.0098 15.5 1.1 0.55 9.8 0.2 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGC37775.1 - 0.0098 16.3 0.0 0.027 14.9 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain ABC_tran PF00005.27 EGC37775.1 - 0.017 15.7 0.4 0.022 15.3 0.4 1.6 1 1 0 1 1 1 0 ABC transporter AAA_18 PF13238.6 EGC37775.1 - 0.024 15.2 0.0 0.046 14.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.17 EGC37775.1 - 0.035 13.8 0.1 0.071 12.8 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase AAA_30 PF13604.6 EGC37775.1 - 0.04 13.7 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC37775.1 - 0.062 13.2 0.3 0.36 10.7 0.1 2.1 2 0 0 2 2 2 0 NACHT domain ATP_bind_1 PF03029.17 EGC37775.1 - 0.087 12.6 0.0 6.1 6.5 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_29 PF13555.6 EGC37775.1 - 0.11 12.2 0.0 0.23 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRP54 PF00448.22 EGC37775.1 - 0.11 12.1 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Vmethyltransf PF01660.17 EGC37775.1 - 0.13 11.2 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase AAA_17 PF13207.6 EGC37775.1 - 0.14 12.6 0.1 0.31 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain OTU PF02338.19 EGC37776.1 - 1.2e-11 45.2 0.0 1.2e-11 45.2 0.0 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease V_ATPase_I PF01496.19 EGC37776.1 - 0.032 12.2 19.3 0.042 11.8 19.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Gsf2 PF11055.8 EGC37777.1 - 0.094 11.5 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 Glucose signalling factor 2 DUF4094 PF13334.6 EGC37779.1 - 0.0045 17.4 0.2 0.012 16.0 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) DUF5080 PF16883.5 EGC37779.1 - 0.0073 16.5 11.7 0.014 15.5 1.9 2.3 1 1 1 2 2 2 2 Domain of unknown function (DUF5080) DUF2232 PF09991.9 EGC37779.1 - 0.15 11.2 3.1 0.24 10.6 3.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DivIC PF04977.15 EGC37779.1 - 0.84 9.5 3.7 0.31 10.8 0.6 1.9 2 0 0 2 2 2 0 Septum formation initiator RNA_pol_Rpb1_1 PF04997.12 EGC37780.1 - 4.6e-114 380.9 1.4 4.6e-114 380.9 1.4 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.17 EGC37780.1 - 9e-105 349.9 0.0 9e-105 349.9 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.20 EGC37780.1 - 1.8e-76 256.0 0.1 1.8e-76 256.0 0.1 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.14 EGC37780.1 - 7.7e-54 182.4 0.1 1.6e-53 181.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.18 EGC37780.1 - 1e-51 175.0 0.0 2.3e-51 173.9 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.12 EGC37780.1 - 1.8e-47 160.7 0.7 6.7e-47 158.9 0.7 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.17 EGC37780.1 - 5e-39 132.6 1.1 5e-39 132.6 1.1 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.13 EGC37780.1 - 5.3e-13 48.6 337.9 0.38 11.2 16.2 15.8 8 1 0 16 16 16 13 RNA polymerase Rpb1 C-terminal repeat TACC_C PF05010.14 EGC37780.1 - 0.12 12.2 1.9 0.29 10.9 1.9 1.6 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Pept_tRNA_hydro PF01195.19 EGC37781.1 - 3.3e-12 46.7 0.0 4.4e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SmpB PF01668.18 EGC37782.1 - 0.0034 17.2 0.3 0.0098 15.8 0.3 1.7 1 0 0 1 1 1 1 SmpB protein TMEM154 PF15102.6 EGC37782.1 - 0.026 14.4 0.1 0.053 13.4 0.1 1.4 1 0 0 1 1 1 0 TMEM154 protein family ETRAMP PF09716.10 EGC37782.1 - 0.06 13.4 2.8 0.26 11.4 0.5 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Insulin_TMD PF17870.1 EGC37782.1 - 0.52 10.4 4.6 0.14 12.2 0.4 2.2 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment DUF4760 PF15956.5 EGC37783.1 - 0.0041 17.3 0.9 0.98 9.5 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF4760) RelA_SpoT PF04607.17 EGC37784.1 - 7.7e-11 42.3 1.1 1.9e-10 41.0 1.1 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins Swm2 PF17083.5 EGC37784.1 - 0.23 11.5 5.3 0.18 11.8 0.5 2.5 1 1 1 2 2 2 0 Nucleolar protein Swm2 Myb_DNA-bind_6 PF13921.6 EGC37784.1 - 0.57 10.5 5.4 4.6 7.6 0.0 3.4 3 1 1 4 4 4 0 Myb-like DNA-binding domain FAD_binding_4 PF01565.23 EGC37785.1 - 2.1e-26 92.3 1.5 3.4e-26 91.6 0.7 1.8 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.12 EGC37785.1 - 0.00077 19.5 1.3 0.0027 17.8 1.3 2.0 1 0 0 1 1 1 1 Berberine and berberine like FAT PF02259.23 EGC37785.1 - 0.012 14.9 0.2 0.023 13.9 0.2 1.4 1 0 0 1 1 1 0 FAT domain YjeF_N PF03853.15 EGC37786.1 - 4.5e-37 127.6 0.0 5.4e-37 127.3 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HAD_2 PF13419.6 EGC37787.1 - 1.3e-10 41.6 4.8 1.2e-08 35.3 4.8 2.2 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGC37787.1 - 1.2e-09 38.8 0.0 2.7e-05 24.6 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase PNK3P PF08645.11 EGC37787.1 - 0.00024 20.8 0.1 0.00055 19.7 0.1 1.6 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD PF12710.7 EGC37787.1 - 0.00032 21.2 0.1 0.015 15.7 0.1 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGC37787.1 - 0.003 17.6 0.0 0.0047 17.0 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EGC37787.1 - 0.018 14.9 0.0 0.16 11.8 0.0 2.1 2 1 0 2 2 2 0 Acid Phosphatase RIC1 PF07064.13 EGC37787.1 - 0.08 12.3 0.1 0.095 12.1 0.1 1.1 1 0 0 1 1 1 0 RIC1 BRCA2 PF00634.18 EGC37788.1 - 9.5e-09 34.8 3.3 0.00051 19.7 0.3 2.3 2 0 0 2 2 2 2 BRCA2 repeat Striatin PF08232.12 EGC37788.1 - 1.9 9.0 12.9 1.8 9.1 11.5 1.6 1 1 1 2 2 2 0 Striatin family Sod_Cu PF00080.20 EGC37789.1 - 5.6e-36 123.8 1.0 7.8e-28 97.4 2.3 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) AF-4 PF05110.13 EGC37789.1 - 0.23 9.5 5.1 0.31 9.1 5.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sod_Cu PF00080.20 EGC37790.1 - 6.9e-34 117.1 1.0 1.3e-23 83.7 0.8 2.1 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) TMEM154 PF15102.6 EGC37791.1 - 0.026 14.4 3.7 1.3 8.9 0.3 2.1 2 0 0 2 2 2 0 TMEM154 protein family DNA_pol3_theta PF06440.11 EGC37791.1 - 0.17 11.6 1.7 0.32 10.7 1.7 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit Shisa PF13908.6 EGC37791.1 - 0.95 9.7 6.0 3.8 7.7 0.4 2.1 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF4041 PF13250.6 EGC37792.1 - 0.019 14.9 2.1 4.9 7.1 0.4 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) Acetyltransf_9 PF13527.7 EGC37793.1 - 4e-05 23.7 0.0 8.3e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC37793.1 - 4.2e-05 23.8 0.0 0.00057 20.1 0.0 2.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC37793.1 - 0.00011 22.5 0.0 0.00025 21.4 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC37793.1 - 0.0021 18.0 0.0 0.0044 17.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC37793.1 - 0.021 15.0 0.0 0.082 13.1 0.0 2.0 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase OMPdecase PF00215.24 EGC37794.1 - 1.9e-75 253.3 0.4 2.6e-75 252.9 0.4 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.27 EGC37794.1 - 1.5e-11 44.1 0.1 2.9e-11 43.1 0.1 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_63 PF03200.16 EGC37795.1 - 3.2e-160 534.1 14.5 4.6e-159 530.3 14.5 2.1 1 1 0 1 1 1 1 Glycosyl hydrolase family 63 C-terminal domain Glyco_hydro_63N PF16923.5 EGC37795.1 - 5.7e-55 186.9 5.1 5.7e-55 186.9 5.1 1.7 2 0 0 2 2 2 1 Glycosyl hydrolase family 63 N-terminal domain Trehalase PF01204.18 EGC37795.1 - 3.9e-07 29.3 0.2 6.1e-07 28.6 0.2 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid6H PF17389.2 EGC37795.1 - 0.0021 17.4 0.0 0.0056 16.0 0.0 1.7 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain SgrT PF15894.5 EGC37795.1 - 0.021 14.8 0.4 0.29 11.1 0.2 2.6 2 0 0 2 2 2 0 Inhibitor of glucose uptake transporter SgrT F-box_4 PF15966.5 EGC37796.1 - 0.083 12.8 1.2 0.27 11.1 0.9 1.9 1 1 1 2 2 2 0 F-box CIMR PF00878.18 EGC37797.1 - 0.00014 22.0 0.8 0.00019 21.6 0.8 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Man-6-P_recep PF02157.15 EGC37797.1 - 0.012 14.7 0.0 0.015 14.4 0.0 1.1 1 0 0 1 1 1 0 Mannose-6-phosphate receptor PAP_assoc PF03828.19 EGC37799.1 - 0.25 11.6 2.4 1.6 9.0 0.4 2.5 2 0 0 2 2 2 0 Cid1 family poly A polymerase Ribonuc_L-PSP PF01042.21 EGC37801.1 - 4.3e-26 91.3 0.0 6.7e-26 90.7 0.0 1.3 1 1 0 1 1 1 1 Endoribonuclease L-PSP Gp_dh_C PF02800.20 EGC37802.1 - 2.6e-68 228.6 0.1 3.6e-68 228.1 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.24 EGC37802.1 - 1.1e-38 131.6 0.2 4.2e-38 129.7 0.0 2.0 2 0 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.20 EGC37802.1 - 0.014 15.5 0.3 0.054 13.6 0.1 2.3 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.19 EGC37802.1 - 0.096 12.0 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.20 EGC37803.1 - 4.3e-43 145.5 0.3 1.9e-32 111.3 0.4 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.6 EGC37803.1 - 4.2e-20 72.4 7.3 4.6e-10 39.7 0.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC37803.1 - 3.4e-10 39.8 3.2 2.6e-06 27.0 0.0 3.2 2 1 1 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGC37803.1 - 3.9e-10 40.2 0.2 0.00011 22.6 0.0 3.6 3 0 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC37803.1 - 2.8e-08 34.0 0.4 0.029 14.7 0.0 3.9 3 2 0 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.6 EGC37803.1 - 0.0002 21.5 0.1 0.03 14.5 0.0 2.7 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.11 EGC37803.1 - 0.001 19.0 0.1 4.3 7.4 0.0 3.4 3 1 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.21 EGC37803.1 - 0.001 19.0 0.1 0.004 17.1 0.1 2.1 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_5 PF13743.6 EGC37803.1 - 0.022 14.5 0.4 14 5.3 0.0 3.5 3 1 1 4 4 4 0 Thioredoxin Thioredoxin_3 PF13192.6 EGC37803.1 - 0.074 13.1 0.1 2.9 8.0 0.1 2.4 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.6 EGC37803.1 - 0.079 12.7 0.0 0.24 11.2 0.0 1.8 2 0 0 2 2 2 0 Thioredoxin Thioredoxin PF00085.20 EGC37804.1 - 9.8e-26 89.7 0.8 1.2e-25 89.4 0.8 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGC37804.1 - 3.3e-07 30.7 0.5 8.6e-07 29.4 0.5 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC37804.1 - 1.1e-05 25.0 1.2 1.7e-05 24.3 1.2 1.3 1 1 0 1 1 1 1 OST3 / OST6 family, transporter family AhpC-TSA PF00578.21 EGC37804.1 - 5.1e-05 23.2 0.2 5.9e-05 23.0 0.2 1.3 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.6 EGC37804.1 - 0.0003 21.1 0.7 0.05 13.9 0.2 2.7 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.6 EGC37804.1 - 0.011 15.5 0.4 0.016 15.0 0.2 1.3 1 1 0 1 1 1 0 Thioredoxin Thioredoxin_3 PF13192.6 EGC37804.1 - 0.021 14.9 0.1 0.038 14.0 0.1 1.3 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.6 EGC37804.1 - 0.063 13.5 0.2 0.11 12.6 0.2 1.6 1 1 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.10 EGC37804.1 - 0.071 12.8 0.0 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Redoxin Citrate_synt PF00285.21 EGC37805.1 - 5.4e-106 354.7 0.0 6.3e-106 354.5 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase, C-terminal domain Proteasome PF00227.26 EGC37806.1 - 5e-60 202.2 0.2 8.9e-60 201.4 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC37806.1 - 5.3e-10 38.8 0.2 3.5e-09 36.2 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature FXa_inhibition PF14670.6 EGC37807.1 - 2.6e-119 389.2 255.6 1.1e-11 44.7 13.9 14.5 14 0 0 14 14 14 12 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGC37807.1 - 4.5e-95 311.0 110.0 9.9e-10 38.2 2.9 14.1 13 0 0 13 13 13 12 Complement Clr-like EGF-like EGF_CA PF07645.15 EGC37807.1 - 4.6e-81 266.8 260.0 2.2e-08 34.1 11.4 14.7 15 0 0 15 15 14 13 Calcium-binding EGF domain EGF_3 PF12947.7 EGC37807.1 - 4.5e-42 141.9 245.6 3.2e-05 24.0 11.3 15.3 15 0 0 15 15 15 13 EGF domain EGF PF00008.27 EGC37807.1 - 5.3e-15 55.4 223.6 0.041 14.2 8.9 14.7 14 0 0 14 14 14 12 EGF-like domain hEGF PF12661.7 EGC37807.1 - 1.6e-10 41.2 203.6 0.14 12.8 7.4 15.9 14 1 0 14 14 13 11 Human growth factor-like EGF Plasmod_Pvs28 PF06247.11 EGC37807.1 - 2.1e-09 37.5 204.6 0.14 12.5 10.0 15.8 12 2 3 15 15 15 12 Pvs28 EGF domain EGF_Tenascin PF18720.1 EGC37807.1 - 6.8e-06 26.0 9.7 6.8e-06 26.0 9.7 4.0 2 0 0 2 2 1 1 Tenascin EGF domain DUF4375 PF14300.6 EGC37807.1 - 2.7e-05 24.4 25.7 21 5.4 0.0 10.1 5 3 5 10 10 10 0 Domain of unknown function (DUF4375) EGF_2 PF07974.13 EGC37807.1 - 0.0064 16.8 13.0 0.0064 16.8 13.0 14.8 14 0 0 14 14 14 1 EGF-like domain TMEM154 PF15102.6 EGC37807.1 - 0.59 10.0 3.6 0.44 10.4 0.3 2.2 2 0 0 2 2 2 0 TMEM154 protein family OTU PF02338.19 EGC37808.1 - 2.4e-14 53.9 1.4 4e-14 53.2 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease SelP_N PF04592.14 EGC37808.1 - 0.0048 16.3 8.4 0.0048 16.3 8.4 2.0 2 0 0 2 2 2 1 Selenoprotein P, N terminal region SRI PF08236.11 EGC37808.1 - 0.022 14.9 1.8 0.17 12.0 0.6 2.5 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain TERB2 PF15101.6 EGC37808.1 - 0.045 13.8 13.8 0.058 13.5 5.9 2.2 2 0 0 2 2 2 0 Telomere-associated protein TERB2 PIEZO PF15917.5 EGC37808.1 - 0.42 10.1 12.9 0.62 9.5 12.4 1.5 1 1 0 1 1 1 0 Piezo zf-B_box PF00643.24 EGC37809.1 - 7.7e-06 26.0 4.0 7.7e-06 26.0 4.0 2.2 2 0 0 2 2 2 1 B-box zinc finger FNIP PF05725.12 EGC37810.1 - 1.6e-66 220.2 35.3 1.3e-17 63.7 1.1 8.2 3 2 3 8 8 8 8 FNIP Repeat WSS_VP PF12175.8 EGC37810.1 - 0.045 13.2 0.2 1.3 8.4 0.0 2.8 2 1 0 2 2 2 0 White spot syndrome virus structural envelope protein VP Helicase_C PF00271.31 EGC37811.1 - 1.4e-19 70.5 0.0 5.3e-17 62.2 0.0 3.0 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC37811.1 - 1.9e-19 70.1 0.0 3.6e-19 69.2 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase RecQ_Zn_bind PF16124.5 EGC37811.1 - 2.8e-17 63.2 2.9 6.7e-17 62.0 2.9 1.7 1 0 0 1 1 1 1 RecQ zinc-binding RQC PF09382.10 EGC37811.1 - 7.6e-16 57.9 0.6 1.7e-15 56.8 0.6 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.15 EGC37811.1 - 4.6e-06 26.8 0.0 1.5e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit KGK PF08872.10 EGC37811.1 - 0.0067 16.9 1.0 0.085 13.4 0.0 2.6 2 0 0 2 2 2 1 KGK domain RNase_H_2 PF13482.6 EGC37811.1 - 0.12 12.3 1.0 2.4 8.1 0.0 2.5 2 1 0 2 2 2 0 RNase_H superfamily Ribosomal_L12 PF00542.19 EGC37811.1 - 0.59 10.5 4.5 4.6 7.7 0.0 3.5 2 1 1 3 3 3 0 Ribosomal protein L7/L12 C-terminal domain OTU PF02338.19 EGC37812.1 - 9e-15 55.3 2.8 2.4e-14 53.9 0.0 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease SRI PF08236.11 EGC37812.1 - 0.013 15.6 2.9 0.047 13.9 0.4 2.5 1 1 1 2 2 2 0 SRI (Set2 Rpb1 interacting) domain TERB2 PF15101.6 EGC37812.1 - 0.05 13.6 15.5 0.059 13.4 7.7 2.3 2 0 0 2 2 2 0 Telomere-associated protein TERB2 Tetraspanin PF00335.20 EGC37812.1 - 0.067 12.9 0.3 0.11 12.1 0.3 1.3 1 0 0 1 1 1 0 Tetraspanin family FAM165 PF14981.6 EGC37812.1 - 0.095 12.5 1.1 0.56 10.0 1.1 2.4 1 0 0 1 1 1 0 FAM165 family PIEZO PF15917.5 EGC37812.1 - 0.32 10.4 14.6 0.79 9.2 14.6 1.7 1 1 0 1 1 1 0 Piezo PAT1 PF09770.9 EGC37812.1 - 7.6 4.7 34.9 10 4.3 34.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FNIP PF05725.12 EGC37813.1 - 9.5e-36 121.7 54.7 2.7e-05 24.2 1.6 11.0 6 3 4 11 11 11 10 FNIP Repeat zf-B_box PF00643.24 EGC37813.1 - 1.7e-05 24.8 4.0 1.7e-05 24.8 4.0 1.9 2 0 0 2 2 2 1 B-box zinc finger Nipped-B_C PF12830.7 EGC37813.1 - 0.44 10.5 3.8 24 4.8 0.2 3.4 3 0 0 3 3 3 0 Sister chromatid cohesion C-terminus FNIP PF05725.12 EGC37814.1 - 5.4e-23 80.9 27.8 7.9e-06 25.9 1.7 5.6 4 1 1 5 5 5 5 FNIP Repeat Nipped-B_C PF12830.7 EGC37814.1 - 0.24 11.3 1.0 7.8 6.4 0.2 2.3 2 0 0 2 2 2 0 Sister chromatid cohesion C-terminus DUF1198 PF06711.11 EGC37815.1 - 0.099 12.7 0.2 0.099 12.7 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1198) FNIP PF05725.12 EGC37816.1 - 5.9e-75 247.2 74.6 1.4e-14 54.0 0.8 10.5 5 3 6 12 12 12 11 FNIP Repeat DUF3689 PF12463.8 EGC37817.1 - 7.5e-22 78.0 20.9 7.5e-22 78.0 20.9 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) DUSP PF06337.12 EGC37819.1 - 4.3e-12 46.5 0.4 4.3e-12 46.5 0.4 5.0 4 2 0 4 4 4 1 DUSP domain PDDEXK_5 PF11645.8 EGC37819.1 - 0.013 15.5 0.4 0.053 13.5 0.4 2.1 1 0 0 1 1 1 0 PD-(D/E)XK endonuclease OTU PF02338.19 EGC37820.1 - 1e-11 45.4 0.1 1.8e-11 44.6 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4834 PF16118.5 EGC37820.1 - 0.006 17.5 2.3 0.006 17.5 2.3 2.8 2 1 0 2 2 2 1 Domain of unknown function (DUF4834) TFIIA PF03153.13 EGC37820.1 - 0.46 10.4 48.0 0.68 9.9 48.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4551 PF15087.6 EGC37820.1 - 0.5 9.1 20.6 0.67 8.7 20.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) O-antigen_lig PF13425.6 EGC37820.1 - 1.1 7.9 9.2 1.5 7.5 9.2 1.3 1 0 0 1 1 1 0 O-antigen ligase like membrane protein PAT1 PF09770.9 EGC37820.1 - 3.5 5.8 33.7 4.7 5.3 33.7 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hid1 PF12722.7 EGC37820.1 - 6.8 4.7 18.5 9.8 4.2 18.5 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUSP PF06337.12 EGC37821.1 - 4.5e-12 46.4 0.8 4.5e-12 46.4 0.8 6.5 4 2 0 4 4 4 1 DUSP domain Glyco_transf_56 PF07429.11 EGC37822.1 - 0.06 12.5 0.3 0.071 12.2 0.3 1.0 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 RRM_1 PF00076.22 EGC37823.1 - 1.2e-16 60.3 0.1 1.8e-16 59.7 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC37823.1 - 4.9e-07 29.8 0.3 1.9e-06 27.9 0.1 2.1 1 1 1 2 2 2 1 RNA recognition motif CIA30 PF08547.12 EGC37824.1 - 5.7e-37 127.2 0.2 7.6e-37 126.8 0.2 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.13 EGC37824.1 - 0.00019 21.3 0.2 0.00029 20.8 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain (family 11) DEAD PF00270.29 EGC37825.1 - 5.5e-42 143.5 0.1 5.5e-42 143.5 0.1 2.6 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC37825.1 - 4e-33 114.1 4.2 2.2e-28 98.8 0.3 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain PA14 PF07691.12 EGC37826.1 - 5.7e-13 48.9 0.6 1e-12 48.1 0.6 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC37826.1 - 0.00014 21.7 4.4 0.00014 21.7 4.4 13.6 14 0 0 14 14 14 4 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC37827.1 - 6.6e-10 39.0 0.2 1.2e-09 38.1 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC37827.1 - 0.00065 19.5 2.0 0.00065 19.5 2.0 13.4 15 0 0 15 15 15 3 Dictyostelium (slime mold) repeat PA14 PF07691.12 EGC37828.1 - 2.1e-21 76.3 0.1 4.6e-21 75.2 0.1 1.6 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.18 EGC37828.1 - 0.0003 20.6 7.3 0.0003 20.6 7.3 14.8 12 4 2 14 14 14 6 Dictyostelium (slime mold) repeat DUF1764 PF08576.10 EGC37830.1 - 5.6e-09 36.8 6.5 5.6e-09 36.8 6.5 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) DUF2981 PF11200.8 EGC37830.1 - 1.1 8.9 8.4 1.3 8.7 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) CDC27 PF09507.10 EGC37830.1 - 1.6 8.1 24.1 1.7 8.0 24.1 1.0 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Iron_traffic PF04362.14 EGC37831.1 - 0.064 13.0 0.0 0.1 12.3 0.0 1.3 1 0 0 1 1 1 0 Bacterial Fe(2+) trafficking Pkinase PF00069.25 EGC37832.1 - 3.6e-56 190.5 0.0 1e-55 189.0 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37832.1 - 2.7e-51 174.4 0.0 4.5e-51 173.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC37832.1 - 0.003 17.0 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC37832.1 - 0.0033 16.3 0.1 0.0033 16.3 0.1 2.7 2 1 0 2 2 2 1 Fungal protein kinase 2-oxoacid_dh PF00198.23 EGC37833.1 - 4.1e-83 278.4 0.0 5e-83 278.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGC37833.1 - 1.2e-17 63.5 2.1 2.4e-17 62.5 2.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_D23 PF16576.5 EGC37833.1 - 0.00015 21.1 0.8 0.00071 18.9 0.1 2.1 2 0 0 2 2 2 1 Barrel-sandwich domain of CusB or HlyD membrane-fusion Biotin_lipoyl_2 PF13533.6 EGC37833.1 - 0.00017 21.4 0.1 0.0011 18.7 0.0 2.3 1 1 1 2 2 2 1 Biotin-lipoyl like GCV_H PF01597.19 EGC37833.1 - 0.00025 20.9 0.4 0.00069 19.5 0.2 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein HlyD_3 PF13437.6 EGC37833.1 - 0.00098 19.8 0.5 0.03 15.0 0.0 2.5 1 1 1 2 2 2 1 HlyD family secretion protein RnfC_N PF13375.6 EGC37833.1 - 0.025 14.5 0.1 0.074 13.0 0.1 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain eIF3_subunit PF08597.10 EGC37833.1 - 1.4 8.8 7.4 2 8.2 7.4 1.1 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit Glyoxalase_4 PF13669.6 EGC37834.1 - 4.4e-18 65.5 0.0 5.4e-18 65.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.25 EGC37834.1 - 1.9e-12 47.5 0.0 2.1e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_3 PF13468.6 EGC37834.1 - 0.00068 19.8 0.0 0.0008 19.6 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Rab3-GTPase_cat PF13890.6 EGC37835.1 - 1.4e-40 138.6 1.4 2.3e-39 134.6 1.4 2.5 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit DUF4834 PF16118.5 EGC37835.1 - 1.9 9.5 9.4 15 6.7 2.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) zf-UBR PF02207.20 EGC37836.1 - 2.7e-18 65.9 15.7 9.6e-18 64.1 15.7 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Ribosomal_S8 PF00410.19 EGC37836.1 - 2.9e-06 27.2 0.0 1.1e-05 25.4 0.0 2.1 1 0 0 1 1 1 1 Ribosomal protein S8 zf-RING_2 PF13639.6 EGC37836.1 - 4.7 7.6 13.8 0.083 13.2 0.3 3.3 2 0 0 2 2 2 0 Ring finger domain MatE PF01554.18 EGC37837.1 - 5.8e-48 162.6 23.7 3.1e-35 121.2 8.0 2.5 3 0 0 3 3 3 2 MatE Polysacc_synt_C PF14667.6 EGC37837.1 - 0.00043 20.4 14.3 0.004 17.2 3.8 3.8 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.18 EGC37838.1 - 1.1e-65 220.2 25.3 4.3e-35 120.8 8.0 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.6 EGC37838.1 - 0.00063 19.8 13.8 0.004 17.2 3.4 4.1 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain GRAM PF02893.20 EGC37839.1 - 8.4e-15 54.6 0.3 2.1e-14 53.4 0.3 1.7 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.8 EGC37839.1 - 3.2e-08 33.7 6.7 8.6e-08 32.4 0.5 2.7 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus SNARE PF05739.19 EGC37839.1 - 0.0011 18.9 6.4 0.017 15.1 0.5 2.5 2 0 0 2 2 2 2 SNARE domain DUF5089 PF17002.5 EGC37839.1 - 0.032 14.1 0.4 0.032 14.1 0.4 2.3 2 1 1 3 3 3 0 Domain of unknown function (DUF5089) Snapin_Pallidin PF14712.6 EGC37839.1 - 1.5 9.3 7.2 5.4 7.5 0.2 2.5 2 0 0 2 2 2 0 Snapin/Pallidin Ank_2 PF12796.7 EGC37840.1 - 0.0018 18.8 0.1 8.2 7.1 0.0 4.1 1 1 1 3 3 3 2 Ankyrin repeats (3 copies) GDPD PF03009.17 EGC37841.1 - 7.1e-38 130.8 0.0 2.3e-37 129.1 0.0 1.7 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.6 EGC37841.1 - 0.076 13.5 0.3 4.3 7.9 0.1 2.4 2 0 0 2 2 2 0 Glycerophosphoryl diester phosphodiesterase family Cpn60_TCP1 PF00118.24 EGC37843.1 - 4.5e-89 299.3 4.3 5.9e-89 298.9 4.3 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family TMEM223 PF14640.6 EGC37844.1 - 0.033 14.4 0.5 8.3 6.6 0.0 2.8 2 0 0 2 2 2 0 Transmembrane protein 223 zf-FLZ PF04570.14 EGC37844.1 - 0.045 13.2 17.1 2.3 7.8 0.6 4.4 4 0 0 4 4 4 0 zinc-finger of the FCS-type, C2-C2 SUA5 PF03481.13 EGC37844.1 - 2 8.9 7.7 40 4.8 0.2 4.0 2 2 0 2 2 2 0 Putative GTP-binding controlling metal-binding Copine PF07002.16 EGC37845.1 - 2.1e-58 197.4 0.4 3.4e-58 196.7 0.1 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.30 EGC37845.1 - 1.5e-17 63.8 0.1 1.9e-08 34.5 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC37845.1 - 4.3e-05 23.7 0.0 8e-05 22.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC37845.1 - 0.012 15.9 0.1 0.034 14.4 0.1 1.8 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4419 PF14388.6 EGC37846.1 - 1.7e-89 300.2 3.4 2e-89 300.0 3.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) PRD_Mga PF08270.11 EGC37846.1 - 0.026 14.2 1.3 1.2 8.8 0.0 2.1 2 0 0 2 2 2 0 M protein trans-acting positive regulator (MGA) PRD domain Rsbr_N PF08678.10 EGC37846.1 - 0.048 13.7 0.3 0.93 9.6 0.0 2.7 3 1 0 3 3 3 0 Rsbr N terminal TIG PF01833.24 EGC37847.1 - 9.1e-07 28.9 11.4 0.0008 19.4 0.2 4.4 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.13 EGC37847.1 - 0.00049 20.4 28.7 0.019 15.3 12.0 2.7 2 0 0 2 2 2 2 EGF-like domain LRR_8 PF13855.6 EGC37847.1 - 0.0085 15.8 16.1 0.4 10.5 1.6 5.6 3 2 1 4 4 4 2 Leucine rich repeat Laminin_EGF PF00053.24 EGC37847.1 - 0.019 15.1 2.5 0.019 15.1 2.5 2.5 2 0 0 2 2 2 0 Laminin EGF domain GST_N_2 PF13409.6 EGC37848.1 - 2e-20 72.8 0.0 3.8e-20 71.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC37848.1 - 3.2e-14 52.7 0.0 5.5e-14 51.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC37848.1 - 3.3e-08 33.6 0.2 6.9e-08 32.6 0.2 1.6 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC37848.1 - 3.5e-07 30.3 0.3 8.2e-07 29.1 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_6 PF17171.4 EGC37848.1 - 0.00044 20.0 0.3 0.0012 18.6 0.3 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC37848.1 - 0.0053 17.1 0.0 0.11 12.9 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain ArAE_1_C PF11728.8 EGC37848.1 - 0.11 12.4 2.6 0.74 9.8 1.0 2.7 2 1 1 3 3 3 0 Putative aromatic acid exporter C-terminal domain Virul_Fac PF10139.9 EGC37848.1 - 0.13 10.5 0.6 0.27 9.4 0.6 1.5 1 1 0 1 1 1 0 Putative bacterial virulence factor GST_N_2 PF13409.6 EGC37849.1 - 1.3e-10 41.5 0.0 2e-10 40.8 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Spectrin_like PF18373.1 EGC37849.1 - 0.037 14.1 0.2 0.076 13.1 0.1 1.5 2 0 0 2 2 2 0 Spectrin like domain GST_N_2 PF13409.6 EGC37850.1 - 2.1e-16 60.0 0.0 3.7e-16 59.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC37850.1 - 8.5e-09 35.3 0.0 1.4e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.6 EGC37850.1 - 5.3e-06 26.7 0.0 0.00012 22.4 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC37850.1 - 3.6e-05 23.5 0.2 7.4e-05 22.5 0.2 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC37850.1 - 0.00029 21.0 0.6 0.00099 19.3 0.4 2.1 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.25 EGC37850.1 - 0.0076 16.4 0.1 0.022 15.0 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.14 EGC37851.1 - 5e-60 202.5 0.2 1.7e-55 187.8 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_lid_9 PF17871.1 EGC37851.1 - 1.6e-36 124.4 0.6 1.6e-36 124.4 0.6 3.0 2 1 1 3 3 3 1 AAA lid domain AAA PF00004.29 EGC37851.1 - 7.2e-27 94.4 0.0 8.4e-14 52.1 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.9 EGC37851.1 - 1.1e-21 76.6 0.5 1.1e-21 76.6 0.5 3.6 4 0 0 4 4 3 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.20 EGC37851.1 - 4.1e-20 71.6 2.8 3e-09 36.9 0.1 3.1 2 0 0 2 2 2 2 Clp amino terminal domain, pathogenicity island component AAA_5 PF07728.14 EGC37851.1 - 1.6e-18 67.0 1.2 1e-11 45.0 0.0 4.2 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC37851.1 - 1.5e-11 45.0 12.4 5.1e-06 27.0 0.1 5.7 4 3 2 7 7 6 2 AAA ATPase domain Sigma54_activat PF00158.26 EGC37851.1 - 6.7e-11 42.2 0.1 4.8e-07 29.6 0.0 3.1 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_22 PF13401.6 EGC37851.1 - 2.3e-09 37.6 0.7 0.018 15.3 0.0 5.3 2 2 1 3 3 3 2 AAA domain IstB_IS21 PF01695.17 EGC37851.1 - 6.2e-08 32.6 0.0 0.0097 15.7 0.0 3.2 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_14 PF13173.6 EGC37851.1 - 6e-07 29.6 0.0 0.059 13.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain TniB PF05621.11 EGC37851.1 - 6.2e-07 29.0 0.2 0.0048 16.3 0.0 4.3 3 1 0 3 3 3 1 Bacterial TniB protein AAA_7 PF12775.7 EGC37851.1 - 3.5e-06 26.7 0.0 0.0097 15.4 0.0 3.0 3 0 0 3 3 2 2 P-loop containing dynein motor region RuvB_N PF05496.12 EGC37851.1 - 3.7e-06 26.8 0.5 0.13 12.0 0.0 4.2 3 1 0 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain ATPase_2 PF01637.18 EGC37851.1 - 6.8e-06 26.2 3.1 0.84 9.5 0.0 4.5 4 2 0 4 4 4 2 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EGC37851.1 - 3.1e-05 24.5 0.0 0.27 11.8 0.0 3.5 2 0 0 2 2 2 2 AAA domain NACHT PF05729.12 EGC37851.1 - 5.1e-05 23.3 0.0 0.21 11.5 0.0 2.9 2 0 0 2 2 2 2 NACHT domain RNA_helicase PF00910.22 EGC37851.1 - 0.0002 21.7 0.0 1.1 9.6 0.0 3.3 3 0 0 3 3 2 2 RNA helicase Roc PF08477.13 EGC37851.1 - 0.00039 20.6 0.0 0.61 10.3 0.0 2.8 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase AAA_23 PF13476.6 EGC37851.1 - 0.00048 20.7 17.0 0.0057 17.2 0.0 3.7 2 1 1 3 3 3 1 AAA domain AAA_24 PF13479.6 EGC37851.1 - 0.00053 19.8 1.3 0.55 9.9 0.0 3.7 4 0 0 4 4 3 1 AAA domain Mg_chelatase PF01078.21 EGC37851.1 - 0.00056 19.3 0.0 1.3 8.3 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI ABC_tran PF00005.27 EGC37851.1 - 0.00059 20.4 1.1 0.35 11.4 0.0 4.0 3 1 0 3 3 3 1 ABC transporter DUF815 PF05673.13 EGC37851.1 - 0.00062 19.0 1.0 0.96 8.6 0.0 3.3 3 1 0 3 3 3 1 Protein of unknown function (DUF815) AAA_28 PF13521.6 EGC37851.1 - 0.00075 19.8 0.0 4.8 7.4 0.0 3.8 3 0 0 3 3 3 0 AAA domain TsaE PF02367.17 EGC37851.1 - 0.00082 19.4 0.0 4.1 7.4 0.0 3.5 4 0 0 4 4 3 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_33 PF13671.6 EGC37851.1 - 0.00088 19.5 0.0 1.1 9.4 0.0 3.0 2 0 0 2 2 2 1 AAA domain RsgA_GTPase PF03193.16 EGC37851.1 - 0.00097 19.1 1.7 5.2 6.9 0.0 4.2 5 0 0 5 5 4 0 RsgA GTPase Zeta_toxin PF06414.12 EGC37851.1 - 0.0011 18.3 0.0 0.21 10.8 0.0 3.1 3 0 0 3 3 2 1 Zeta toxin DNA_pol3_delta2 PF13177.6 EGC37851.1 - 0.0013 18.5 0.0 0.034 13.9 0.0 3.2 2 1 0 2 2 2 1 DNA polymerase III, delta subunit DUF87 PF01935.17 EGC37851.1 - 0.0014 18.8 4.9 0.31 11.1 0.0 4.1 4 0 0 4 4 4 1 Helicase HerA, central domain AAA_25 PF13481.6 EGC37851.1 - 0.0014 18.2 1.1 0.25 10.9 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.11 EGC37851.1 - 0.0031 17.4 0.1 1.8 8.5 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_31 PF13614.6 EGC37851.1 - 0.0045 16.9 0.1 2.5 8.0 0.3 3.3 3 0 0 3 3 2 1 AAA domain AAA_30 PF13604.6 EGC37851.1 - 0.0057 16.4 0.2 5.5 6.7 0.0 3.9 3 1 0 3 3 3 0 AAA domain ResIII PF04851.15 EGC37851.1 - 0.0062 16.6 0.0 0.91 9.5 0.0 3.9 4 0 0 4 4 3 1 Type III restriction enzyme, res subunit Rx_N PF18052.1 EGC37851.1 - 0.012 15.9 2.7 0.5 10.7 0.8 3.5 2 1 1 3 3 3 0 Rx N-terminal domain T2SSE PF00437.20 EGC37851.1 - 0.022 13.8 0.0 0.063 12.3 0.0 1.8 1 0 0 1 1 1 0 Type II/IV secretion system protein PhoH PF02562.16 EGC37851.1 - 0.036 13.5 0.1 0.9 8.9 0.0 3.1 4 0 0 4 4 3 0 PhoH-like protein AAA_19 PF13245.6 EGC37851.1 - 0.037 14.4 0.1 0.81 10.0 0.1 3.1 3 1 0 3 3 2 0 AAA domain SRP54 PF00448.22 EGC37851.1 - 0.044 13.4 0.1 13 5.3 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_29 PF13555.6 EGC37851.1 - 0.088 12.6 0.0 13 5.6 0.0 2.6 2 0 0 2 2 2 0 P-loop containing region of AAA domain FlxA PF14282.6 EGC37851.1 - 2.9 7.9 9.5 2.2 8.3 1.8 3.1 1 1 0 2 2 2 0 FlxA-like protein DUF724 PF05266.14 EGC37851.1 - 9.9 5.9 8.2 3.2 7.5 4.5 2.2 2 0 0 2 2 1 0 Protein of unknown function (DUF724) FAD_binding_3 PF01494.19 EGC37853.1 - 2.9e-19 69.6 0.0 5.7e-19 68.6 0.0 1.4 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.6 EGC37853.1 - 0.0017 18.5 0.0 0.0036 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.10 EGC37853.1 - 0.0026 16.8 0.0 0.015 14.4 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.24 EGC37853.1 - 0.032 13.8 0.0 0.073 12.6 0.0 1.6 2 0 0 2 2 2 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.6 EGC37853.1 - 0.038 13.2 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.17 EGC37853.1 - 0.057 12.7 0.0 0.093 12.0 0.0 1.3 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.6 EGC37853.1 - 0.14 12.1 0.0 0.3 11.1 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Amidohydro_2 PF04909.14 EGC37854.1 - 5.2e-18 65.8 0.0 7.7e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase DDE_Tnp_IS1 PF03400.13 EGC37854.1 - 0.082 13.2 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 IS1 transposase SepSecS PF05889.13 EGC37855.1 - 1.6e-127 425.4 0.0 4.9e-127 423.8 0.0 1.6 1 1 0 1 1 1 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Beta_elim_lyase PF01212.21 EGC37855.1 - 0.00031 20.1 0.0 0.00041 19.7 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Med22 PF06179.12 EGC37856.1 - 5.7e-23 81.1 7.8 7.6e-23 80.7 7.8 1.2 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex DUF1084 PF06454.11 EGC37857.1 - 4.5e-11 42.6 32.6 1.4e-10 41.0 32.6 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) NmrA PF05368.13 EGC37858.1 - 1.6e-39 135.9 0.0 1.9e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC37858.1 - 2.6e-16 60.0 0.0 3.4e-16 59.7 0.0 1.1 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC37858.1 - 3.8e-06 26.1 0.1 8.8e-06 24.9 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.10 EGC37858.1 - 0.00027 20.9 0.0 0.0013 18.7 0.0 1.9 2 0 0 2 2 2 1 KR domain Epimerase PF01370.21 EGC37858.1 - 0.0038 16.7 0.0 0.021 14.3 0.0 1.9 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family adh_short PF00106.25 EGC37858.1 - 0.048 13.1 0.1 0.091 12.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase Fer2_4 PF13510.6 EGC37858.1 - 0.067 13.2 0.0 4.7 7.3 0.0 2.3 2 0 0 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DapB_N PF01113.20 EGC37858.1 - 0.071 13.2 0.7 0.11 12.6 0.1 1.7 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.24 EGC37858.1 - 0.11 12.9 0.1 0.35 11.3 0.1 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.17 EGC37858.1 - 0.13 12.9 0.1 0.25 12.0 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.16 EGC37858.1 - 0.14 11.8 0.0 0.24 11.1 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA TAFII55_N PF04658.13 EGC37859.1 - 6.1e-37 126.8 1.6 6.1e-37 126.8 1.6 2.1 2 0 0 2 2 2 1 TAFII55 protein conserved region Secretin_N_2 PF07655.13 EGC37859.1 - 0.02 15.4 7.8 0.02 15.4 7.8 6.9 5 2 0 5 5 5 0 Secretin N-terminal domain Snapin_Pallidin PF14712.6 EGC37859.1 - 5.4 7.5 14.3 3.3 8.2 0.1 2.8 2 0 0 2 2 2 0 Snapin/Pallidin VMA21 PF09446.10 EGC37860.1 - 1.5e-12 47.4 5.8 2.1e-12 47.0 5.8 1.2 1 0 0 1 1 1 1 VMA21-like domain GET2 PF08690.10 EGC37860.1 - 0.0026 17.5 8.2 0.0036 17.0 8.2 1.2 1 0 0 1 1 1 1 GET complex subunit GET2 DUF4407 PF14362.6 EGC37860.1 - 0.015 14.7 0.9 0.022 14.1 0.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) TFIIF_alpha PF05793.12 EGC37860.1 - 0.16 10.6 28.1 0.19 10.3 28.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Myc_N PF01056.18 EGC37860.1 - 0.3 10.9 15.6 0.44 10.4 15.6 1.3 1 0 0 1 1 1 0 Myc amino-terminal region LAP1C PF05609.12 EGC37860.1 - 0.58 9.2 12.2 0.7 8.9 12.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF1673 PF07895.11 EGC37860.1 - 0.62 9.7 3.9 0.12 12.1 0.4 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) SAPS PF04499.15 EGC37860.1 - 0.83 8.4 9.1 1.5 7.5 9.1 1.4 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein GREB1 PF15782.5 EGC37860.1 - 1.6 5.7 11.7 1.8 5.6 11.7 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SLC12 PF03522.15 EGC37860.1 - 1.8 7.5 10.9 2.2 7.2 10.9 1.2 1 0 0 1 1 1 0 Solute carrier family 12 Utp14 PF04615.13 EGC37860.1 - 3.1 6.3 26.8 3.8 6.0 26.8 1.0 1 0 0 1 1 1 0 Utp14 protein Ndc1_Nup PF09531.10 EGC37860.1 - 4.9 5.7 8.4 6.5 5.3 8.4 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Pox_Ag35 PF03286.14 EGC37860.1 - 7.1 6.4 28.6 0.072 12.9 15.3 2.1 1 1 1 2 2 2 0 Pox virus Ag35 surface protein Lin-8 PF03353.15 EGC37860.1 - 8.7 5.8 19.2 11 5.4 19.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Pyr_redox_2 PF07992.14 EGC37861.1 - 8.1e-68 228.8 11.0 1.1e-67 228.3 11.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.22 EGC37861.1 - 1e-40 138.4 0.1 3.1e-40 136.9 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.27 EGC37861.1 - 1.2e-20 73.8 12.9 3.3e-18 66.0 1.0 3.2 4 0 0 4 4 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGC37861.1 - 3e-09 36.7 1.0 3e-09 36.7 1.0 2.5 2 1 1 3 3 3 1 FAD dependent oxidoreductase GIDA PF01134.22 EGC37861.1 - 1.7e-08 34.0 9.7 6.4e-08 32.1 3.6 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.6 EGC37861.1 - 6.9e-08 32.1 14.8 1.5e-05 24.4 3.5 2.5 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.6 EGC37861.1 - 3.4e-07 30.4 3.4 0.00013 22.1 1.3 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.14 EGC37861.1 - 6.9e-07 28.3 13.2 0.00015 20.7 2.5 3.8 3 1 1 4 4 4 2 HI0933-like protein FAD_binding_2 PF00890.24 EGC37861.1 - 4.8e-06 25.9 18.8 1.2e-05 24.6 2.5 4.2 3 1 2 5 5 5 2 FAD binding domain AlaDh_PNT_C PF01262.21 EGC37861.1 - 0.00011 21.6 7.1 0.17 11.1 0.1 3.5 3 1 0 3 3 3 2 Alanine dehydrogenase/PNT, C-terminal domain K_oxygenase PF13434.6 EGC37861.1 - 0.00042 19.6 5.0 0.0085 15.3 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) Thi4 PF01946.17 EGC37861.1 - 0.00062 19.1 10.0 0.016 14.5 4.8 2.9 1 1 1 2 2 2 2 Thi4 family Lycopene_cycl PF05834.12 EGC37861.1 - 0.00084 18.5 6.1 0.13 11.2 0.0 3.1 2 1 1 3 3 3 2 Lycopene cyclase protein Mqo PF06039.15 EGC37861.1 - 0.0049 15.5 2.0 0.13 10.8 0.2 2.4 1 1 1 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Amino_oxidase PF01593.24 EGC37861.1 - 0.0067 15.8 3.7 0.53 9.5 0.1 3.0 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.19 EGC37861.1 - 0.012 14.8 2.7 0.012 14.8 2.7 3.0 2 1 0 2 2 2 0 FAD binding domain 3HCDH_N PF02737.18 EGC37861.1 - 0.039 13.9 0.3 0.039 13.9 0.3 2.2 2 0 0 2 2 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DAO PF01266.24 EGC37861.1 - 0.17 11.4 20.0 0.42 10.2 1.3 4.1 3 1 1 4 4 4 0 FAD dependent oxidoreductase NAD_binding_7 PF13241.6 EGC37861.1 - 1.9 9.0 5.0 3 8.3 0.4 2.8 3 1 0 3 3 2 0 Putative NAD(P)-binding FNIP PF05725.12 EGC37862.1 - 5.2e-48 161.0 15.2 3.1e-14 52.8 0.2 6.2 6 0 0 6 6 6 6 FNIP Repeat LRR_5 PF13306.6 EGC37862.1 - 2.7e-05 24.1 6.2 0.04 13.9 0.7 2.6 3 0 0 3 3 3 2 BspA type Leucine rich repeat region (6 copies) HTH_46 PF15977.5 EGC37862.1 - 0.009 16.0 0.0 0.021 14.8 0.0 1.6 1 0 0 1 1 1 1 Winged helix-turn-helix DNA binding XisH PF08814.10 EGC37864.1 - 0.037 14.2 0.2 0.15 12.2 0.0 2.0 2 0 0 2 2 2 0 XisH protein PAP_RNA-bind PF04926.15 EGC37864.1 - 0.12 12.1 1.3 0.48 10.0 1.2 1.9 1 1 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain ETRAMP PF09716.10 EGC37865.1 - 2.3 8.3 7.2 8 6.6 7.2 2.0 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Ribosomal_L27e PF01777.18 EGC37866.1 - 6.9e-30 103.2 4.3 8.3e-30 103.0 4.3 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family zf-RING_2 PF13639.6 EGC37867.1 - 4.1e-12 46.2 9.2 5.9e-12 45.7 9.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC37867.1 - 3.7e-10 39.4 8.0 7.4e-10 38.4 8.0 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGC37867.1 - 2.4e-06 27.3 10.2 3.8e-06 26.7 10.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC37867.1 - 0.00011 22.2 8.7 0.00019 21.4 8.7 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.6 EGC37867.1 - 0.00018 21.2 10.0 0.00032 20.5 10.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC37867.1 - 0.00032 20.6 8.9 0.00048 20.0 8.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.7 EGC37867.1 - 0.00032 20.9 11.9 0.0012 19.1 11.9 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC37867.1 - 0.00073 19.4 5.6 0.001 18.8 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGC37867.1 - 0.0012 18.9 6.3 0.003 17.6 6.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.7 EGC37867.1 - 0.0057 16.8 6.9 0.012 15.8 6.9 1.5 1 1 0 1 1 1 1 RING-variant domain zf-P11 PF03854.14 EGC37867.1 - 0.052 13.2 7.9 0.11 12.1 7.9 1.6 1 1 0 1 1 1 0 P-11 zinc finger Zn_ribbon_17 PF17120.5 EGC37867.1 - 0.065 12.9 7.2 0.11 12.1 7.2 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_4 PF14570.6 EGC37867.1 - 0.08 12.7 9.0 0.14 12.0 9.0 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain CTU2 PF10288.9 EGC37867.1 - 0.5 10.6 4.2 24 5.2 4.2 2.1 1 1 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 FANCL_C PF11793.8 EGC37867.1 - 0.89 9.8 8.7 2.5 8.4 8.7 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.6 EGC37867.1 - 1.2 9.3 6.9 2.7 8.2 6.9 1.6 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FNIP PF05725.12 EGC37868.1 - 1.7e-17 63.3 18.1 3.1e-07 30.4 0.9 4.3 1 1 3 4 4 4 4 FNIP Repeat FNIP PF05725.12 EGC37869.1 - 1.6e-34 117.8 2.3 8e-09 35.5 0.4 7.2 4 3 3 7 7 7 6 FNIP Repeat Pkinase PF00069.25 EGC37869.1 - 1.4e-32 113.1 0.1 2e-32 112.6 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37869.1 - 5.1e-19 68.6 0.0 7.6e-19 68.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC37869.1 - 9.2e-05 21.4 0.3 0.00013 20.8 0.3 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC37869.1 - 0.00045 19.6 0.7 0.001 18.4 0.7 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC37869.1 - 0.0033 16.4 0.3 0.0071 15.3 0.3 1.5 1 0 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC37869.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.4 1 0 0 1 1 1 0 Kinase-like RIO1 PF01163.22 EGC37869.1 - 0.041 13.5 0.2 0.078 12.6 0.2 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGC37869.1 - 0.15 12.0 0.1 0.49 10.3 0.1 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family SR1P PF13790.6 EGC37870.1 - 0.057 13.5 0.3 0.1 12.7 0.3 1.4 1 0 0 1 1 1 0 SR1 protein UPF0182 PF03699.13 EGC37870.1 - 0.16 10.0 1.5 0.19 9.8 1.5 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) TarH PF02203.15 EGC37870.1 - 0.81 9.6 0.1 0.81 9.6 0.1 2.0 2 0 0 2 2 2 0 Tar ligand binding domain homologue CrgA PF06781.12 EGC37870.1 - 1.7 8.7 6.7 0.35 10.9 0.3 2.6 1 1 1 2 2 2 0 Cell division protein CrgA Cytochrom_B_C PF00032.17 EGC37871.1 - 0.35 11.2 4.5 1.1 9.6 2.3 2.2 2 0 0 2 2 2 0 Cytochrome b(C-terminal)/b6/petD VIT1 PF01988.19 EGC37871.1 - 1.9 8.3 9.9 0.22 11.4 4.3 2.0 2 0 0 2 2 2 0 VIT family Mito_carr PF00153.27 EGC37872.1 - 3.4e-67 222.4 1.8 4.1e-21 74.7 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PAS_3 PF08447.12 EGC37873.1 - 1.4e-15 57.3 0.0 3e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.25 EGC37873.1 - 1.5e-11 44.3 0.0 3.2e-08 33.6 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.7 EGC37873.1 - 3.5e-08 33.7 0.0 2.1e-06 27.9 0.0 3.0 2 1 0 2 2 2 1 PAS domain PAS_4 PF08448.10 EGC37873.1 - 2.9e-05 24.3 0.0 0.0033 17.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold PAS_8 PF13188.7 EGC37873.1 - 0.00065 19.7 0.0 0.93 9.6 0.0 2.6 2 0 0 2 2 2 2 PAS domain Hist_deacetyl PF00850.19 EGC37874.1 - 1.7e-70 238.0 0.1 3.7e-70 236.8 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain AT_hook PF02178.19 EGC37874.1 - 0.21 11.6 2.3 9.7 6.5 0.6 3.0 2 0 0 2 2 2 0 AT hook motif DUF4419 PF14388.6 EGC37875.1 - 4.2e-94 315.4 1.2 4.2e-94 315.4 1.2 2.0 2 0 0 2 2 2 2 Domain of unknown function (DUF4419) KH_6 PF15985.5 EGC37877.1 - 7e-13 48.7 0.0 1.6e-12 47.6 0.0 1.6 1 0 0 1 1 1 1 KH domain ECR1_N PF14382.6 EGC37877.1 - 1e-10 41.2 0.0 1.7e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region EXOSC1 PF10447.9 EGC37877.1 - 0.052 14.1 2.4 4.9 7.8 0.1 3.5 2 2 1 4 4 4 0 Exosome component EXOSC1/CSL4 MciZ PF13072.6 EGC37877.1 - 8.4 6.3 7.0 0.82 9.5 1.9 2.0 2 0 0 2 2 2 0 Mother cell inhibitor of FtsZ EF-hand_7 PF13499.6 EGC37878.1 - 8.5e-07 29.3 1.1 1.7e-06 28.3 0.1 2.0 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.6 EGC37878.1 - 9e-05 22.1 0.2 0.0045 16.8 0.1 2.7 2 0 0 2 2 2 1 EF-hand domain EF-hand_1 PF00036.32 EGC37878.1 - 0.00013 21.2 0.2 0.0025 17.2 0.1 2.8 3 0 0 3 3 3 1 EF hand Porph_ging PF09697.10 EGC37878.1 - 0.085 13.4 0.7 0.46 11.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) EF_assoc_1 PF08355.12 EGC37878.1 - 0.092 12.3 0.0 0.23 11.1 0.0 1.7 1 0 0 1 1 1 0 EF hand associated TPR_8 PF13181.6 EGC37878.1 - 0.1 12.8 0.2 0.1 12.8 0.2 2.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37878.1 - 0.25 11.2 2.9 0.75 9.7 0.2 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane_3 PF12698.7 EGC37880.1 - 6.9e-58 196.4 66.0 1e-34 120.2 32.4 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.27 EGC37880.1 - 2.8e-51 173.6 0.1 4.3e-25 88.8 0.1 2.6 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.6 EGC37880.1 - 2.9e-14 53.6 0.6 2e-05 24.5 0.0 4.8 5 0 0 5 5 5 3 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC37880.1 - 2.8e-05 23.6 0.0 1.6 8.1 0.0 3.7 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC37880.1 - 0.00022 20.9 1.5 0.01 15.6 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Rad17 PF03215.15 EGC37880.1 - 0.00063 19.7 0.0 0.089 12.7 0.0 2.7 2 0 0 2 2 2 1 Rad17 P-loop domain SRP54 PF00448.22 EGC37880.1 - 0.00089 18.9 1.5 0.51 9.9 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain ABC2_membrane PF01061.24 EGC37880.1 - 0.019 14.4 46.5 0.055 12.9 18.1 4.3 4 0 0 4 4 4 0 ABC-2 type transporter AAA_23 PF13476.6 EGC37880.1 - 0.019 15.4 7.3 0.45 11.0 0.1 3.3 3 0 0 3 3 3 0 AAA domain SbcCD_C PF13558.6 EGC37880.1 - 0.024 14.9 0.0 2.8 8.2 0.0 3.5 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit RsgA_GTPase PF03193.16 EGC37880.1 - 0.075 12.9 0.6 2.3 8.1 0.1 2.4 2 0 0 2 2 2 0 RsgA GTPase AAA_30 PF13604.6 EGC37880.1 - 0.11 12.1 0.1 7.7 6.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain EGF_2 PF07974.13 EGC37882.1 - 0.00013 22.2 11.8 0.00023 21.5 11.8 1.4 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGC37882.1 - 0.0028 17.7 11.7 0.0054 16.8 11.7 1.4 1 0 0 1 1 1 1 Tenascin EGF domain EB PF01683.18 EGC37882.1 - 0.028 14.7 5.5 0.056 13.7 5.5 1.4 1 0 0 1 1 1 0 EB module hEGF PF12661.7 EGC37882.1 - 0.029 15.0 3.8 0.061 14.0 3.8 1.6 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.27 EGC37882.1 - 0.045 14.1 5.6 0.08 13.3 5.6 1.4 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 EGC37883.1 - 0.00016 22.0 11.8 0.00029 21.1 11.8 1.5 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGC37883.1 - 0.0033 17.4 11.7 0.0069 16.4 11.7 1.5 1 0 0 1 1 1 1 Tenascin EGF domain hEGF PF12661.7 EGC37883.1 - 0.034 14.8 3.8 0.078 13.6 3.8 1.7 1 0 0 1 1 1 0 Human growth factor-like EGF EB PF01683.18 EGC37883.1 - 0.034 14.4 5.6 0.08 13.3 5.6 1.5 1 0 0 1 1 1 0 EB module EGF PF00008.27 EGC37883.1 - 0.055 13.8 5.6 0.1 12.9 5.6 1.5 1 0 0 1 1 1 0 EGF-like domain SHMT PF00464.19 EGC37884.1 - 4.3e-183 608.4 0.0 5.1e-183 608.2 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.21 EGC37884.1 - 1.2e-05 24.7 0.0 9e-05 21.8 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGC37884.1 - 0.00071 18.9 0.0 0.0046 16.3 0.0 1.9 1 1 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.19 EGC37884.1 - 0.0012 17.9 0.0 0.0027 16.7 0.0 1.3 1 1 0 1 1 1 1 Aminotransferase class-V FERM_M PF00373.18 EGC37885.1 - 3.8e-49 166.0 4.2 1.6e-23 83.3 0.4 3.4 3 0 0 3 3 3 2 FERM central domain FERM_N PF09379.10 EGC37885.1 - 5.1e-25 87.2 0.0 1.8e-11 43.8 0.2 4.6 4 1 0 4 4 4 2 FERM N-terminal domain FERM_f0 PF16511.5 EGC37885.1 - 2.9e-14 53.1 6.1 3.9e-08 33.5 0.0 5.1 5 0 0 5 5 5 3 N-terminal or F0 domain of Talin-head FERM ACBP PF00887.19 EGC37885.1 - 9e-06 25.8 0.1 0.32 11.2 0.0 3.3 3 0 0 3 3 3 2 Acyl CoA binding protein IRS PF02174.17 EGC37885.1 - 0.00051 19.9 0.0 0.0094 15.8 0.0 2.7 2 0 0 2 2 2 1 PTB domain (IRS-1 type) DUF3439 PF11921.8 EGC37885.1 - 2.3 8.2 10.0 6.7 6.7 10.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETC_C1_NDUFA5 PF04716.14 EGC37887.1 - 1.5e-24 85.6 0.5 2.3e-24 85.0 0.5 1.3 1 0 0 1 1 1 1 ETC complex I subunit conserved region Omega_Repress PF07764.11 EGC37887.1 - 0.063 13.8 0.2 0.099 13.2 0.2 1.4 1 0 0 1 1 1 0 Omega Transcriptional Repressor ADH_N_2 PF16884.5 EGC37887.1 - 0.067 13.1 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 N-terminal domain of oxidoreductase ALS_ss_C PF10369.9 EGC37887.1 - 0.087 13.0 0.5 0.14 12.4 0.5 1.3 1 0 0 1 1 1 0 Small subunit of acetolactate synthase FATC PF02260.20 EGC37887.1 - 0.14 12.0 0.0 0.4 10.6 0.0 1.7 2 0 0 2 2 2 0 FATC domain EB PF01683.18 EGC37888.1 - 0.0077 16.5 11.2 0.0077 16.5 11.2 7.8 2 1 4 6 6 6 3 EB module Cas6b_C PF17262.2 EGC37889.1 - 0.14 12.3 5.9 1.2 9.2 0.0 2.6 2 0 0 2 2 2 0 Cas6b C-terminal domain FAR1 PF03101.15 EGC37890.1 - 0.05 14.3 6.0 3.9 8.2 6.0 2.9 1 1 0 1 1 1 0 FAR1 DNA-binding domain Homeodomain PF00046.29 EGC37892.1 - 2.3e-10 40.2 0.2 2.3e-10 40.2 0.2 2.1 2 0 0 2 2 2 1 Homeodomain Cleaved_Adhesin PF07675.11 EGC37893.1 - 0.013 15.5 0.1 0.017 15.0 0.1 1.2 1 0 0 1 1 1 0 Cleaved Adhesin Domain fn3 PF00041.21 EGC37893.1 - 0.014 15.7 0.2 0.027 14.8 0.2 1.5 1 0 0 1 1 1 0 Fibronectin type III domain HORMA PF02301.18 EGC37893.1 - 0.015 14.9 0.9 0.024 14.3 0.9 1.4 1 0 0 1 1 1 0 HORMA domain Pga1 PF10333.9 EGC37893.1 - 0.36 10.7 9.3 4.1 7.2 9.0 2.3 1 1 0 1 1 1 0 GPI-Mannosyltransferase II co-activator ODV-E18 PF10717.9 EGC37893.1 - 7.4 6.5 7.4 19 5.2 0.2 3.6 5 0 0 5 5 5 0 Occlusion-derived virus envelope protein ODV-E18 DUF4042 PF13251.6 EGC37894.1 - 1.9e-34 118.9 1.7 1.3e-15 57.6 0.7 4.2 4 0 0 4 4 4 2 Domain of unknown function (DUF4042) HEAT PF02985.22 EGC37894.1 - 3.2e-14 51.8 0.5 0.22 11.9 0.0 7.5 7 0 0 7 7 7 4 HEAT repeat HEAT_EZ PF13513.6 EGC37894.1 - 1.7e-11 44.3 0.2 0.12 12.9 0.1 6.8 7 1 1 8 8 8 4 HEAT-like repeat HEAT_2 PF13646.6 EGC37894.1 - 3e-08 33.9 0.0 0.25 11.8 0.0 4.1 3 1 0 4 4 4 3 HEAT repeats Arm PF00514.23 EGC37894.1 - 0.0038 17.2 8.9 12 6.2 0.7 6.1 5 2 1 6 6 6 1 Armadillo/beta-catenin-like repeat IFRD PF05004.13 EGC37894.1 - 0.023 13.8 2.9 1.3 8.1 0.3 3.6 3 1 1 4 4 4 0 Interferon-related developmental regulator (IFRD) FAM131 PF15010.6 EGC37894.1 - 4.7 7.0 9.1 31 4.4 0.0 3.0 3 0 0 3 3 3 0 Putative cell signalling Arf PF00025.21 EGC37895.1 - 6.2e-63 211.4 0.0 7e-63 211.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.20 EGC37895.1 - 1.4e-11 44.2 0.0 2e-08 33.8 0.0 2.3 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.10 EGC37895.1 - 9.8e-09 34.9 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGC37895.1 - 1.6e-08 34.3 0.0 1.8e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC37895.1 - 7.5e-08 32.6 0.0 1.7e-07 31.5 0.0 1.5 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase MMR_HSR1 PF01926.23 EGC37895.1 - 2.2e-05 24.5 0.0 4.4e-05 23.5 0.0 1.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC37895.1 - 0.00015 21.2 0.0 0.0002 20.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGC37895.1 - 0.2 11.4 0.0 0.39 10.5 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.27 EGC37895.1 - 0.2 11.2 0.0 7.4 6.1 0.0 2.0 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain Actin PF00022.19 EGC37896.1 - 2.2e-114 382.2 0.0 1.7e-113 379.3 0.0 1.9 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.13 EGC37896.1 - 0.00023 20.1 0.0 0.0004 19.3 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein PYRIN PF02758.16 EGC37896.1 - 0.061 13.5 0.1 0.18 12.0 0.0 1.8 2 0 0 2 2 2 0 PAAD/DAPIN/Pyrin domain TRAPPC10 PF12584.8 EGC37898.1 - 3e-11 43.3 0.0 9.4e-11 41.6 0.0 1.9 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.8 EGC37898.1 - 1.6e-08 34.4 0.2 4.3e-07 29.8 0.1 2.4 2 0 0 2 2 2 1 Foie gras liver health family 1 SNAP PF14938.6 EGC37898.1 - 0.04 13.4 0.5 2.3 7.5 0.0 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_16 PF13432.6 EGC37898.1 - 0.055 14.1 0.3 4.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37898.1 - 0.075 12.9 3.1 0.12 12.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC37898.1 - 0.78 10.0 3.1 0.86 9.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Bac_surface_Ag PF01103.23 EGC37899.1 - 0.0095 15.5 4.4 0.0091 15.5 4.4 1.0 1 0 0 1 1 1 1 Surface antigen Sigma70_r3 PF04539.16 EGC37900.1 - 0.0033 17.5 0.0 0.73 10.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-70 region 3 AI-2E_transport PF01594.16 EGC37900.1 - 0.039 13.1 0.2 0.064 12.4 0.2 1.3 1 0 0 1 1 1 0 AI-2E family transporter TFIIE_alpha PF02002.17 EGC37900.1 - 0.12 12.2 1.9 0.17 11.7 0.1 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit UPF0154 PF03672.13 EGC37900.1 - 0.13 12.3 0.4 11 6.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Arm PF00514.23 EGC37901.1 - 2.9e-63 208.1 10.9 6.1e-11 42.0 0.0 8.7 8 0 0 8 8 8 8 Armadillo/beta-catenin-like repeat IBB PF01749.20 EGC37901.1 - 1e-13 51.5 2.5 1.9e-13 50.6 2.5 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT_2 PF13646.6 EGC37901.1 - 2.1e-11 44.0 0.0 0.0024 18.2 0.0 4.5 2 2 2 4 4 4 3 HEAT repeats HEAT_EZ PF13513.6 EGC37901.1 - 9.7e-11 41.9 2.2 0.0017 18.9 0.1 5.8 6 2 0 6 6 6 3 HEAT-like repeat HEAT PF02985.22 EGC37901.1 - 4.1e-08 32.8 1.0 0.1 12.9 0.0 6.4 8 0 0 8 8 8 1 HEAT repeat Arm_3 PF16186.5 EGC37901.1 - 1.6e-06 27.6 1.3 9.4e-06 25.1 2.0 2.0 2 0 0 2 2 2 1 Atypical Arm repeat RICTOR_V PF14668.6 EGC37901.1 - 0.14 12.4 8.7 5.6 7.3 0.0 4.7 4 2 2 6 6 6 0 Rapamycin-insensitive companion of mTOR, domain 5 DUF4355 PF14265.6 EGC37901.1 - 2.5 8.3 5.4 18 5.6 5.4 2.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4355) Gemini_AL2 PF01440.16 EGC37902.1 - 1.1 9.7 4.4 0.22 12.0 0.9 1.7 2 0 0 2 2 2 0 Geminivirus AL2 protein YEATS PF03366.16 EGC37903.1 - 1.5e-25 88.9 0.3 3.8e-25 87.7 0.3 1.7 1 0 0 1 1 1 1 YEATS family zf-Di19 PF05605.12 EGC37903.1 - 0.92 9.9 4.1 0.49 10.7 1.1 2.1 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ABC_tran PF00005.27 EGC37905.1 - 5.2e-05 23.8 0.0 0.00024 21.6 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.6 EGC37905.1 - 0.09 13.1 0.0 1.3 9.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain SMC_N PF02463.19 EGC37905.1 - 0.16 11.4 5.8 0.084 12.3 0.8 2.8 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain MtN3_slv PF03083.16 EGC37906.1 - 7.4e-21 74.0 23.5 3.7e-13 49.3 7.3 2.9 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange DctQ PF04290.12 EGC37906.1 - 0.29 11.0 10.8 0.64 9.9 0.4 2.6 1 1 1 2 2 2 0 Tripartite ATP-independent periplasmic transporters, DctQ component RIC3 PF15361.6 EGC37906.1 - 0.42 11.0 2.8 1.8 8.9 0.0 2.2 2 0 0 2 2 2 0 Resistance to inhibitors of cholinesterase homologue 3 FAM176 PF14851.6 EGC37906.1 - 0.64 9.7 4.9 32 4.2 4.3 2.2 2 0 0 2 2 2 0 FAM176 family YfhO PF09586.10 EGC37906.1 - 4.5 5.4 19.7 0.0095 14.2 9.8 1.6 2 0 0 2 2 2 0 Bacterial membrane protein YfhO RRM_1 PF00076.22 EGC37907.1 - 2.1e-16 59.5 0.1 4e-16 58.6 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC37907.1 - 7.3e-05 22.6 0.0 0.00012 21.9 0.0 1.3 1 0 0 1 1 1 1 Occluded RNA-recognition motif RRM_7 PF16367.5 EGC37907.1 - 0.0034 17.5 0.0 0.092 12.9 0.0 2.4 1 1 0 1 1 1 1 RNA recognition motif Nup35_RRM_2 PF14605.6 EGC37907.1 - 0.017 15.1 0.0 0.029 14.4 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGC37907.1 - 0.019 14.6 0.0 0.032 13.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Pet20 PF08692.10 EGC37908.1 - 0.11 13.2 3.4 0.13 13.0 3.4 1.2 1 0 0 1 1 1 0 Mitochondrial protein Pet20 OmpH PF03938.14 EGC37908.1 - 0.12 12.7 10.2 0.14 12.5 10.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Goodbye PF17109.5 EGC37908.1 - 0.15 12.5 4.6 0.22 12.0 4.6 1.3 1 0 0 1 1 1 0 fungal STAND N-terminal Goodbye domain NEMO PF11577.8 EGC37908.1 - 0.18 11.9 12.1 0.24 11.5 12.1 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO TERB2 PF15101.6 EGC37908.1 - 0.29 11.2 4.9 0.33 11.0 4.9 1.0 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Ax_dynein_light PF10211.9 EGC37908.1 - 0.61 10.0 12.8 0.75 9.7 12.8 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain Atrophin-1 PF03154.15 EGC37908.1 - 0.72 8.1 5.2 0.79 7.9 5.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF573 PF04504.14 EGC37908.1 - 0.78 10.4 10.0 0.98 10.1 9.6 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF573 SseC PF04888.12 EGC37908.1 - 0.96 9.0 13.3 1.2 8.7 13.3 1.1 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family NEMP PF10225.9 EGC37908.1 - 1.1 8.9 3.3 1.1 8.8 3.3 1.0 1 0 0 1 1 1 0 NEMP family ATP-synt_E PF05680.12 EGC37908.1 - 1.6 9.1 9.8 2.1 8.8 9.8 1.2 1 0 0 1 1 1 0 ATP synthase E chain DUF3987 PF13148.6 EGC37908.1 - 2.3 7.1 5.3 2.4 7.1 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TMPIT PF07851.13 EGC37908.1 - 2.4 7.3 7.4 2.7 7.1 7.4 1.0 1 0 0 1 1 1 0 TMPIT-like protein EMC3_TMCO1 PF01956.16 EGC37908.1 - 3 7.6 6.9 3 7.6 6.9 1.1 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like U1snRNP70_N PF12220.8 EGC37908.1 - 3.2 8.5 12.7 5.5 7.7 12.7 1.4 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Metallophos PF00149.28 EGC37909.1 - 5.8e-39 134.7 0.1 7.4e-39 134.4 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGC37909.1 - 5.7e-05 23.5 0.7 0.00013 22.3 0.7 1.6 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGC37909.1 - 0.036 14.3 0.0 0.054 13.7 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain zf-RING_2 PF13639.6 EGC37911.1 - 1.4e-06 28.6 10.9 1.4e-06 28.6 10.9 2.8 3 0 0 3 3 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC37911.1 - 4.8e-05 23.1 10.1 4.8e-05 23.1 10.1 2.6 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37911.1 - 0.00011 22.0 7.3 0.00011 22.0 7.3 2.3 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC37911.1 - 0.00059 19.6 11.8 0.00059 19.6 11.8 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC37911.1 - 0.0025 18.1 10.0 0.0025 18.1 10.0 3.3 2 2 0 2 2 2 1 RING-H2 zinc finger domain zf-TRAF PF02176.18 EGC37911.1 - 0.0038 17.9 21.4 0.01 16.5 4.7 4.0 3 1 1 4 4 3 2 TRAF-type zinc finger Glyco_hydro_57 PF03065.15 EGC37911.1 - 0.0039 16.5 2.5 0.0065 15.7 2.5 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 Prok-RING_4 PF14447.6 EGC37911.1 - 0.005 16.7 7.9 0.017 15.0 7.9 2.0 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC37911.1 - 0.018 15.1 8.1 0.018 15.1 8.1 2.5 2 1 0 2 2 2 0 zinc RING finger of MSL2 zf-RING_UBOX PF13445.6 EGC37911.1 - 0.018 15.0 6.6 0.018 15.0 6.6 3.1 3 0 0 3 3 3 0 RING-type zinc-finger zf-RING_5 PF14634.6 EGC37911.1 - 0.019 14.9 9.2 0.019 14.9 9.2 3.6 4 2 0 4 4 3 0 zinc-RING finger domain Acid_PPase PF12689.7 EGC37911.1 - 0.054 13.3 1.8 0.11 12.4 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase U-box PF04564.15 EGC37911.1 - 0.062 13.5 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 U-box domain zf-ACC PF17848.1 EGC37911.1 - 0.13 12.4 0.0 0.13 12.4 0.0 4.0 4 0 0 4 4 3 0 Acetyl-coA carboxylase zinc finger domain CLU PF13236.6 EGC37913.1 - 2.7e-60 203.9 1.3 1.3e-58 198.5 0.0 2.6 2 0 0 2 2 2 1 Clustered mitochondria TPR_17 PF13431.6 EGC37913.1 - 1.7e-13 49.9 0.8 0.0087 16.4 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat eIF3_p135 PF12807.7 EGC37913.1 - 1e-06 28.9 0.0 1e-06 28.9 0.0 3.8 4 0 0 4 4 3 1 Translation initiation factor eIF3 subunit 135 TPR_2 PF07719.17 EGC37913.1 - 1.1e-05 25.2 3.3 0.066 13.3 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37913.1 - 1.2e-05 24.9 1.4 0.17 11.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC37913.1 - 8.2e-05 23.0 0.0 0.084 13.4 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37913.1 - 0.00013 21.9 0.1 0.033 14.4 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC37913.1 - 0.00095 19.8 0.0 0.13 13.2 0.0 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC37913.1 - 0.0025 17.4 0.0 0.016 14.9 0.0 2.3 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.6 EGC37913.1 - 0.037 14.3 0.2 2.2 8.6 0.1 2.7 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC37913.1 - 0.073 13.7 0.0 0.16 12.6 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC37913.1 - 0.13 12.5 0.1 0.39 11.0 0.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 DCP2 PF05026.13 EGC37914.1 - 1e-13 51.4 1.1 1e-13 51.4 1.1 3.1 2 1 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.28 EGC37914.1 - 2.9e-13 50.0 0.0 8.1e-13 48.6 0.0 1.7 1 0 0 1 1 1 1 NUDIX domain Metallophos PF00149.28 EGC37915.1 - 1.1e-39 137.0 0.1 1.5e-39 136.7 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Glyco_hydro_65N PF03636.15 EGC37915.1 - 0.14 11.7 0.0 0.21 11.2 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain TAD2 PF18521.1 EGC37915.1 - 0.35 10.9 1.9 0.79 9.8 1.9 1.5 1 0 0 1 1 1 0 Transactivation domain 2 zf-Di19 PF05605.12 EGC37916.1 - 9.9e-12 45.0 14.4 1.9e-11 44.1 9.8 2.7 3 0 0 3 3 3 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.6 EGC37916.1 - 1.2e-07 31.9 5.3 1.2e-07 31.9 5.3 4.1 3 1 1 4 4 4 2 Ring finger domain SPRY PF00622.28 EGC37916.1 - 3.6e-07 30.3 0.7 8.7e-07 29.1 0.3 1.9 2 0 0 2 2 2 1 SPRY domain zf-C3HC4_2 PF13923.6 EGC37916.1 - 2.4e-06 27.3 4.2 2.4e-06 27.3 4.2 4.1 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC37916.1 - 1.1e-05 25.1 5.4 1.1e-05 25.1 5.4 2.1 2 0 0 2 2 2 1 RING-like zinc finger zf-RING-like PF08746.11 EGC37916.1 - 0.0044 17.3 4.5 0.0044 17.3 4.5 3.1 3 0 0 3 3 3 1 RING-like domain zf-C3HC4_3 PF13920.6 EGC37916.1 - 0.036 13.9 19.4 3.9 7.4 0.2 4.3 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) FSA_C PF10479.9 EGC37916.1 - 0.14 10.3 3.9 0.18 9.9 3.9 1.1 1 0 0 1 1 1 0 Fragile site-associated protein C-terminus zf-C2H2_9 PF16293.5 EGC37916.1 - 0.27 11.1 0.1 0.27 11.1 0.1 3.5 2 1 1 3 3 3 0 C2H2 type zinc-finger (1 copy) Rad50_zn_hook PF04423.14 EGC37916.1 - 0.32 10.9 9.1 7.5 6.5 0.1 4.2 4 0 0 4 4 4 0 Rad50 zinc hook motif Mucin PF01456.17 EGC37916.1 - 0.59 10.1 14.4 1.5 8.8 14.4 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-C2H2_4 PF13894.6 EGC37916.1 - 0.99 10.4 15.5 6.7 7.8 0.0 4.4 4 0 0 4 4 3 0 C2H2-type zinc finger zf-C3HC4 PF00097.25 EGC37916.1 - 2.7 7.9 24.4 0.039 13.8 5.8 4.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) ATP-synt_10 PF05176.14 EGC37917.1 - 1.4e-26 93.3 1.4 1.7e-26 93.0 1.4 1.1 1 0 0 1 1 1 1 ATP10 protein FNIP PF05725.12 EGC37918.1 - 5.3e-57 189.8 21.2 2e-15 56.6 0.3 5.1 4 1 1 5 5 5 5 FNIP Repeat DUF1769 PF08588.10 EGC37918.1 - 7.4e-05 22.9 1.1 3 8.1 0.1 4.3 4 0 0 4 4 4 3 Protein of unknown function (DUF1769) LRR_5 PF13306.6 EGC37918.1 - 0.52 10.3 4.0 0.97 9.4 2.3 2.1 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) Skp1 PF01466.19 EGC37919.1 - 9.5e-30 102.5 1.5 9.5e-30 102.5 1.5 1.8 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.15 EGC37919.1 - 3.7e-29 100.7 3.3 4.5e-29 100.4 2.1 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Glyco_hydro_cc PF11790.8 EGC37921.1 - 1.8e-48 165.2 2.2 2.3e-48 164.9 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DAO PF01266.24 EGC37922.1 - 1.2e-41 143.5 0.0 1.5e-41 143.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Glu_dehyd_C PF16912.5 EGC37922.1 - 0.042 13.3 0.0 9.7 5.6 0.0 2.2 2 0 0 2 2 2 0 Glucose dehydrogenase C-terminus FAD_binding_3 PF01494.19 EGC37922.1 - 0.081 12.2 0.0 0.14 11.4 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain CBM49 PF09478.10 EGC37923.1 - 1.2e-12 48.0 1.9 1.9e-12 47.3 1.9 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 NDK PF00334.19 EGC37925.1 - 7.4e-53 178.2 0.0 8.3e-53 178.0 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Nup192 PF11894.8 EGC37926.1 - 1.4e-43 148.5 87.0 6.1e-37 126.5 48.6 4.3 4 0 0 4 4 4 3 Nuclear pore complex scaffold, nucleoporins 186/192/205 RICTOR_M PF14666.6 EGC37926.1 - 2.2 8.1 7.7 1.1 9.0 0.3 4.3 3 0 0 3 3 3 0 Rapamycin-insensitive companion of mTOR, middle domain TFIIA PF03153.13 EGC37926.1 - 3.8 7.4 22.5 6.2 6.7 6.5 2.5 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.20 EGC37928.1 - 3.2e-23 82.4 1.5 3.7e-23 82.3 1.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Big_3_4 PF13754.6 EGC37928.1 - 0.1 12.3 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function EF1_GNE PF00736.19 EGC37929.1 - 2.5e-31 107.7 0.7 5.6e-31 106.6 0.7 1.6 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain WWE PF02825.20 EGC37929.1 - 1.5e-14 54.3 4.9 6.1e-08 33.1 0.4 2.8 2 0 0 2 2 2 2 WWE domain PARP PF00644.20 EGC37929.1 - 3.6e-14 52.8 0.3 2.4e-13 50.1 0.1 2.3 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain zf-CCHH PF10283.9 EGC37929.1 - 5.6e-10 39.0 3.2 1.4e-09 37.7 3.2 1.7 1 0 0 1 1 1 1 PBZ domain BRCT PF00533.26 EGC37929.1 - 3.7e-07 30.4 3.9 4.9e-07 30.0 0.1 3.0 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGC37929.1 - 2.7e-06 27.2 0.3 7.1e-06 25.9 0.3 1.7 1 0 0 1 1 1 1 twin BRCT domain EF-1_beta_acid PF10587.9 EGC37929.1 - 0.00077 19.9 7.4 0.00077 19.9 7.4 2.8 2 0 0 2 2 1 1 Eukaryotic elongation factor 1 beta central acidic region BRCT_3 PF18428.1 EGC37929.1 - 0.0094 16.0 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain GST_C PF00043.25 EGC37929.1 - 0.047 13.9 0.6 0.19 12.0 0.0 2.4 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain Hira PF07569.11 EGC37929.1 - 0.051 13.3 1.9 0.11 12.1 1.9 1.6 1 0 0 1 1 1 0 TUP1-like enhancer of split GST_C_6 PF17171.4 EGC37929.1 - 0.057 13.2 0.0 0.14 12.0 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Pex14_N PF04695.13 EGC37929.1 - 0.6 10.7 29.6 0.16 12.6 17.6 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kei1 PF08552.11 EGC37929.1 - 1.2 9.0 4.2 16 5.3 0.0 3.1 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 DUF3439 PF11921.8 EGC37929.1 - 2.6 8.0 10.7 8 6.5 10.7 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC37929.1 - 2.9 7.9 23.0 8.6 6.3 23.0 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein BRCT_2 PF16589.5 EGC37930.1 - 5.5e-07 29.9 1.4 5.5e-07 29.9 1.4 2.7 1 1 1 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC37930.1 - 5.8e-06 26.2 0.1 1.5e-05 24.9 0.1 1.7 1 0 0 1 1 1 1 twin BRCT domain LIG3_BRCT PF16759.5 EGC37930.1 - 0.015 15.6 1.5 0.022 15.1 0.2 2.0 2 0 0 2 2 2 0 DNA ligase 3 BRCT domain Mnd1 PF03962.15 EGC37930.1 - 0.038 14.3 1.1 0.073 13.4 0.3 1.9 2 0 0 2 2 2 0 Mnd1 HTH domain Menin PF05053.13 EGC37930.1 - 2.4 6.4 20.1 0.99 7.7 5.8 2.1 2 0 0 2 2 2 0 Menin PulA_N1 PF17999.1 EGC37931.1 - 8 7.3 7.4 1.3 9.9 0.3 3.2 3 1 0 3 3 3 0 Pullulanase N1-terminal domain Voldacs PF03517.13 EGC37932.1 - 2.8e-32 111.7 3.9 3.8e-32 111.3 3.9 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.8 EGC37932.1 - 0.004 17.3 0.0 0.0077 16.4 0.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 TM_PBP2_N PF16296.5 EGC37932.1 - 0.15 12.2 0.0 0.33 11.1 0.0 1.5 1 0 0 1 1 1 0 N-terminal of TM subunit in PBP-dependent ABC transporters Myb_DNA-binding PF00249.31 EGC37933.1 - 0.00015 21.9 0.1 0.0096 16.1 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF2120 PF09893.9 EGC37933.1 - 0.34 11.0 4.0 0.9 9.6 0.8 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2120) PDEase_I PF00233.19 EGC37934.1 - 3.7e-81 272.3 8.7 3.7e-81 272.3 8.7 1.8 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.24 EGC37934.1 - 2e-27 95.6 0.4 4.6e-27 94.4 0.4 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.11 EGC37934.1 - 0.0098 16.3 0.0 0.18 12.2 0.0 2.9 2 0 0 2 2 2 1 Flagellar regulatory protein FleQ FliG_N PF14842.6 EGC37934.1 - 0.03 14.9 6.4 0.2 12.2 1.5 4.0 4 1 0 4 4 4 0 FliG N-terminal domain HD PF01966.22 EGC37934.1 - 0.1 12.8 0.7 0.32 11.2 0.0 2.2 2 0 0 2 2 2 0 HD domain Methyltransf_5 PF01795.19 EGC37935.1 - 1.7e-83 280.7 0.0 2.1e-83 280.4 0.0 1.0 1 0 0 1 1 1 1 MraW methylase family Arf PF00025.21 EGC37936.1 - 6.6e-67 224.3 0.0 7.6e-67 224.1 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC37936.1 - 4.3e-13 49.5 0.1 7.9e-13 48.7 0.1 1.4 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase SRPRB PF09439.10 EGC37936.1 - 7.5e-13 48.3 0.0 9e-13 48.0 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC37936.1 - 4.4e-11 42.6 2.7 4.5e-08 32.6 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGC37936.1 - 1.6e-09 37.5 0.0 2.2e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.12 EGC37936.1 - 5.4e-07 29.2 0.1 8.5e-07 28.6 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC37936.1 - 6.2e-07 29.5 0.0 8.9e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase 6PF2K PF01591.18 EGC37936.1 - 0.063 12.6 0.2 0.32 10.3 0.2 1.9 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.6 EGC37936.1 - 0.19 11.9 0.5 2.2 8.4 0.5 2.2 1 1 0 1 1 1 0 AAA domain Tup_N PF08581.10 EGC37937.1 - 0.029 14.7 0.7 0.082 13.2 0.7 1.7 1 0 0 1 1 1 0 Tup N-terminal MAP17 PF15807.5 EGC37938.1 - 0.013 15.8 1.0 0.024 14.9 0.1 1.9 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Stealth_CR2 PF11380.8 EGC37938.1 - 0.026 14.7 0.1 0.1 12.8 0.0 2.1 1 1 1 2 2 2 0 Stealth protein CR2, conserved region 2 TPR_2 PF07719.17 EGC37939.1 - 6.4e-09 35.3 1.1 0.00096 19.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC37939.1 - 1.3e-07 31.1 7.7 0.00011 21.8 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC37939.1 - 1.9e-05 24.5 3.7 0.003 17.7 0.0 2.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC37939.1 - 0.00024 21.2 0.0 0.00087 19.4 0.0 1.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC37939.1 - 0.0049 16.5 0.8 0.076 12.7 0.0 2.8 2 1 1 3 3 3 1 TPR repeat TPR_12 PF13424.6 EGC37939.1 - 0.0055 17.0 1.0 0.57 10.5 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC37939.1 - 0.0066 17.2 0.6 0.11 13.4 0.1 2.6 2 1 1 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC37939.1 - 0.017 15.2 1.0 2.6 8.2 0.0 3.1 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat BTAD PF03704.17 EGC37939.1 - 0.033 14.6 0.0 2.5 8.5 0.0 2.1 1 1 1 2 2 2 0 Bacterial transcriptional activator domain TPR_17 PF13431.6 EGC37939.1 - 0.043 14.2 0.2 14 6.3 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC37939.1 - 0.064 13.8 0.5 2.5 8.7 0.1 2.6 1 1 0 2 2 2 0 Tetratricopeptide repeat MIT PF04212.18 EGC37939.1 - 0.083 13.0 0.1 0.083 13.0 0.1 3.1 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain DUF4083 PF13314.6 EGC37939.1 - 0.79 9.7 3.6 0.58 10.1 1.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) ABC_membrane PF00664.23 EGC37940.1 - 2.6e-67 227.4 51.5 8.4e-36 124.0 18.9 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC37940.1 - 2.2e-48 164.3 0.2 4.5e-29 101.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGC37940.1 - 0.00063 19.7 0.1 0.26 11.2 0.0 2.4 2 0 0 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC37940.1 - 0.0012 18.9 0.5 1.1 9.4 0.1 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_22 PF13401.6 EGC37940.1 - 0.014 15.7 0.3 2.7 8.3 0.0 2.9 3 0 0 3 3 3 0 AAA domain T2SSE PF00437.20 EGC37940.1 - 0.014 14.5 0.1 0.37 9.8 0.0 2.2 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.6 EGC37940.1 - 0.038 14.5 9.7 0.58 10.6 0.2 3.4 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGC37940.1 - 0.065 13.0 1.0 2.8 7.7 0.3 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_7 PF12775.7 EGC37940.1 - 0.091 12.3 0.1 3.7 7.0 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region AAA PF00004.29 EGC37940.1 - 0.096 13.1 1.1 3.4 8.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.6 EGC37940.1 - 0.097 13.2 0.8 4 8.0 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.6 EGC37940.1 - 0.11 12.8 0.0 6.6 7.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGC37940.1 - 0.13 12.0 0.0 0.68 9.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF2362 PF10154.9 EGC37941.1 - 2.9e-81 273.9 51.5 2.1e-39 135.8 0.2 3.3 1 1 2 3 3 3 3 Uncharacterized conserved protein (DUF2362) Myb_DNA-bind_7 PF15963.5 EGC37942.1 - 6.6e-26 90.0 3.8 6.6e-26 90.0 3.8 4.3 3 1 2 5 5 5 1 Myb DNA-binding like Myb_DNA-binding PF00249.31 EGC37942.1 - 0.0037 17.4 0.1 0.0076 16.4 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain SPRY PF00622.28 EGC37943.1 - 1.2e-68 228.7 11.6 1.7e-24 86.2 0.5 3.7 3 0 0 3 3 3 3 SPRY domain Pkinase_Tyr PF07714.17 EGC37943.1 - 4.6e-67 226.0 0.0 6.6e-67 225.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC37943.1 - 2.8e-49 167.9 0.0 4.5e-49 167.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.17 EGC37943.1 - 1.1e-15 57.4 0.1 2.3e-15 56.4 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.30 EGC37943.1 - 1.8e-14 53.9 0.0 3.7e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase_fungal PF17667.1 EGC37943.1 - 0.027 13.2 8.0 0.55 8.9 7.8 2.4 1 1 0 1 1 1 0 Fungal protein kinase OAD_beta PF03977.13 EGC37944.1 - 0.091 11.7 1.3 0.12 11.4 1.2 1.2 1 1 0 1 1 1 0 Na+-transporting oxaloacetate decarboxylase beta subunit Coiled PF05710.12 EGC37945.1 - 2.5e-07 31.4 2.9 3.1e-07 31.1 2.9 1.1 1 0 0 1 1 1 1 Coiled coil Gly-zipper_YMGG PF13441.6 EGC37945.1 - 0.34 10.7 12.5 0.65 9.8 12.5 1.5 1 0 0 1 1 1 0 YMGG-like Gly-zipper Coiled PF05710.12 EGC37946.1 - 0.051 14.4 6.3 0.23 12.3 6.3 1.8 1 1 0 1 1 1 0 Coiled coil ETRAMP PF09716.10 EGC37946.1 - 0.077 13.1 0.3 0.11 12.6 0.3 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Mito_fiss_reg PF05308.11 EGC37947.1 - 0.0058 16.8 6.3 0.0058 16.8 6.3 2.6 3 0 0 3 3 3 1 Mitochondrial fission regulator FMN_dh PF01070.18 EGC37948.1 - 8.2e-135 449.3 0.0 9.6e-135 449.1 0.0 1.0 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.15 EGC37948.1 - 1.3e-08 34.6 0.1 2.4e-08 33.8 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.25 EGC37948.1 - 9.5e-08 31.4 2.4 9.2e-07 28.2 0.3 2.8 3 1 0 3 3 3 1 IMP dehydrogenase / GMP reductase domain ThiG PF05690.14 EGC37948.1 - 2.4e-07 30.3 0.1 0.0024 17.3 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG Glu_synthase PF01645.17 EGC37948.1 - 3.7e-05 23.0 0.3 7.4e-05 22.1 0.1 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.21 EGC37948.1 - 5.2e-05 22.8 0.3 0.0029 17.1 0.1 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.21 EGC37948.1 - 0.0001 21.6 0.3 0.00075 18.8 0.2 2.5 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase G3P_antiterm PF04309.12 EGC37948.1 - 0.00011 21.7 0.0 0.23 10.9 0.0 2.4 2 0 0 2 2 2 2 Glycerol-3-phosphate responsive antiterminator PA PF02225.22 EGC37948.1 - 0.003 17.5 0.0 19 5.4 0.1 3.3 2 1 1 3 3 3 0 PA domain TMP-TENI PF02581.17 EGC37948.1 - 0.0046 16.3 0.1 0.069 12.5 0.0 2.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase FlpD PF02662.16 EGC37948.1 - 0.08 12.9 0.0 0.92 9.5 0.0 2.3 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit PIN_2 PF10130.9 EGC37948.1 - 0.14 12.4 0.1 0.29 11.4 0.1 1.5 1 0 0 1 1 1 0 PIN domain p450 PF00067.22 EGC37949.1 - 2.2e-81 274.0 0.2 3.2e-81 273.4 0.2 1.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGC37950.1 - 2e-74 251.0 2.1 2.4e-74 250.8 2.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 Plasmod_dom_1 PF09715.10 EGC37950.1 - 0.0099 15.9 1.8 0.0099 15.9 1.8 3.1 2 1 0 2 2 2 1 Plasmodium protein of unknown function (Plasmod_dom_1) BTB_2 PF02214.22 EGC37950.1 - 0.021 15.2 0.1 0.083 13.2 0.1 2.0 1 0 0 1 1 1 0 BTB/POZ domain p450 PF00067.22 EGC37951.1 - 0.0013 17.5 0.1 0.0016 17.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.22 EGC37952.1 - 4e-64 217.1 3.0 4.5e-64 216.9 3.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Plasmod_dom_1 PF09715.10 EGC37952.1 - 0.057 13.5 0.8 0.057 13.5 0.8 2.5 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Gpi16 PF04113.14 EGC37953.1 - 1.3e-142 476.2 2.8 1.9e-140 469.0 2.8 2.9 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Phage_CI_C PF16452.5 EGC37954.1 - 2.9 8.2 9.0 6.2 7.2 0.8 3.2 2 1 1 3 3 3 0 Bacteriophage CI repressor C-terminal domain Pkinase PF00069.25 EGC37955.1 - 6.2e-54 183.1 0.0 8.4e-54 182.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37955.1 - 7.2e-33 114.0 0.0 9.7e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC37955.1 - 9.7e-06 25.1 0.0 1.9e-05 24.1 0.0 1.4 1 1 0 1 1 1 1 Kinase-like FTA2 PF13095.6 EGC37955.1 - 0.0049 16.5 0.2 2.3 7.8 0.1 2.3 1 1 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 Cse1 PF08506.10 EGC37956.1 - 3.2e-109 365.2 8.5 3.7e-109 364.9 7.5 1.7 2 0 0 2 2 2 1 Cse1 CAS_CSE1 PF03378.15 EGC37956.1 - 1.7e-90 303.6 7.5 1.7e-90 303.6 7.5 2.2 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.19 EGC37956.1 - 6e-11 42.1 0.0 1.4e-09 37.8 0.0 3.2 2 0 0 2 2 2 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGC37956.1 - 0.0012 19.0 0.6 0.0012 19.0 0.6 4.6 3 1 1 4 4 4 1 Exportin 1-like protein Glyco_transf_22 PF03901.17 EGC37957.1 - 4.7e-102 342.3 34.6 7.1e-102 341.7 34.6 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family AF-4 PF05110.13 EGC37957.1 - 0.00017 19.9 4.8 0.00017 19.9 4.8 5.1 2 1 2 4 4 4 1 AF-4 proto-oncoprotein BcrAD_BadFG PF01869.20 EGC37958.1 - 1.9e-39 135.8 0.0 2.2e-39 135.6 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family ROK PF00480.20 EGC37958.1 - 0.028 13.9 0.1 1.4 8.3 0.0 2.3 2 0 0 2 2 2 0 ROK family N2227 PF07942.12 EGC37958.1 - 0.086 12.0 0.0 7.4 5.7 0.0 2.3 3 0 0 3 3 3 0 N2227-like protein Beach PF02138.18 EGC37959.1 - 8.8e-117 389.4 2.2 1.7e-116 388.4 2.2 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.32 EGC37959.1 - 1.1e-15 57.7 19.4 0.00085 20.1 2.1 6.8 7 0 0 7 7 7 4 WD domain, G-beta repeat PH_BEACH PF14844.6 EGC37959.1 - 2.1e-14 53.4 0.1 9.4e-12 44.9 0.0 3.5 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH WD40_like PF17005.5 EGC37959.1 - 6.9e-13 48.6 7.8 5.5e-09 35.8 0.8 3.0 2 1 1 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 EGC37959.1 - 2.9e-10 40.3 0.1 0.0087 16.3 0.0 4.7 2 2 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain GRAM PF02893.20 EGC37959.1 - 4.2e-06 26.6 0.7 0.00028 20.8 0.1 2.7 2 0 0 2 2 2 1 GRAM domain Ge1_WD40 PF16529.5 EGC37959.1 - 0.0047 15.9 0.1 1.7 7.5 0.0 2.7 2 1 1 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein BBS2_Mid PF14783.6 EGC37959.1 - 0.0051 16.8 1.1 0.16 12.0 0.0 3.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region S_100 PF01023.19 EGC37959.1 - 0.023 14.4 0.2 0.059 13.1 0.2 1.6 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain ERG4_ERG24 PF01222.17 EGC37960.1 - 2.6e-125 418.6 26.7 3.1e-125 418.3 26.7 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family AAA PF00004.29 EGC37961.1 - 1.7e-39 135.3 0.0 4.1e-39 134.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.10 EGC37961.1 - 6.9e-28 96.4 0.0 2.5e-26 91.4 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.18 EGC37961.1 - 1.4e-20 73.1 8.2 1.4e-20 73.1 8.2 2.0 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_lid_3 PF17862.1 EGC37961.1 - 1.6e-08 34.2 0.0 4.3e-08 32.8 0.0 1.7 1 0 0 1 1 1 1 AAA+ lid domain RuvB_N PF05496.12 EGC37961.1 - 6.2e-06 26.0 0.0 1.3e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_22 PF13401.6 EGC37961.1 - 1.9e-05 24.9 0.4 0.014 15.7 0.4 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.6 EGC37961.1 - 3.4e-05 23.9 0.1 0.00013 22.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC37961.1 - 4.1e-05 24.0 0.1 0.00038 20.9 0.1 2.3 2 1 0 2 2 1 1 AAA ATPase domain DUF815 PF05673.13 EGC37961.1 - 5.2e-05 22.5 0.0 0.0001 21.6 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.13 EGC37961.1 - 6.5e-05 22.3 0.0 0.00012 21.4 0.0 1.4 1 0 0 1 1 1 1 TIP49 P-loop domain AAA_5 PF07728.14 EGC37961.1 - 0.00012 22.1 0.0 0.00029 20.8 0.0 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGC37961.1 - 0.00028 21.0 0.3 0.0025 18.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGC37961.1 - 0.00034 21.0 0.0 0.0012 19.2 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_24 PF13479.6 EGC37961.1 - 0.00041 20.1 5.0 0.0019 18.0 0.1 2.4 2 1 0 2 2 2 1 AAA domain IstB_IS21 PF01695.17 EGC37961.1 - 0.00068 19.4 0.0 0.0016 18.2 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein ATPase PF06745.13 EGC37961.1 - 0.0016 17.9 0.5 0.36 10.1 0.1 2.5 1 1 0 2 2 2 1 KaiC AAA_18 PF13238.6 EGC37961.1 - 0.0027 18.3 0.3 0.017 15.7 0.0 2.4 2 1 0 2 2 2 1 AAA domain TniB PF05621.11 EGC37961.1 - 0.015 14.8 0.4 3.1 7.1 0.0 3.0 3 0 0 3 3 3 0 Bacterial TniB protein NACHT PF05729.12 EGC37961.1 - 0.015 15.2 0.0 0.59 10.0 0.0 2.3 1 1 1 2 2 2 0 NACHT domain AAA_17 PF13207.6 EGC37961.1 - 0.021 15.2 0.1 0.1 13.0 0.0 2.1 2 0 0 2 2 2 0 AAA domain Tma16 PF11176.8 EGC37961.1 - 0.022 14.6 3.1 0.045 13.6 3.1 1.5 1 0 0 1 1 1 0 Translation machinery-associated protein 16 AAA_25 PF13481.6 EGC37961.1 - 0.023 14.3 0.2 0.23 11.0 0.1 2.2 1 1 0 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC37961.1 - 0.023 14.9 0.5 0.073 13.2 0.0 2.2 2 1 0 2 2 1 0 AAA domain Mg_chelatase PF01078.21 EGC37961.1 - 0.029 13.8 0.0 0.064 12.6 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.18 EGC37961.1 - 0.035 13.8 0.1 0.089 12.5 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGC37961.1 - 0.037 14.0 3.7 2 8.3 0.0 2.9 3 0 0 3 3 3 0 ATPase domain predominantly from Archaea AAA_7 PF12775.7 EGC37961.1 - 0.044 13.3 0.4 0.19 11.2 0.1 2.2 2 1 0 2 2 1 0 P-loop containing dynein motor region Bac_DnaA PF00308.18 EGC37961.1 - 0.048 13.5 0.0 0.37 10.6 0.0 2.2 2 1 0 2 2 2 0 Bacterial dnaA protein Torsin PF06309.11 EGC37961.1 - 0.048 13.8 0.0 0.16 12.1 0.0 1.8 2 0 0 2 2 1 0 Torsin Zeta_toxin PF06414.12 EGC37961.1 - 0.051 12.8 0.1 0.94 8.7 0.0 2.5 1 1 1 2 2 2 0 Zeta toxin Parvo_NS1 PF01057.17 EGC37961.1 - 0.058 12.5 0.9 0.091 11.8 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 PhoH PF02562.16 EGC37961.1 - 0.073 12.5 0.0 0.22 11.0 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Use1 PF09753.9 EGC37961.1 - 0.081 12.6 6.5 0.12 12.1 4.7 2.0 2 0 0 2 2 2 0 Membrane fusion protein Use1 Zot PF05707.12 EGC37961.1 - 0.088 12.4 0.3 1.4 8.5 0.1 2.3 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) ABC_tran PF00005.27 EGC37961.1 - 0.13 12.8 0.4 0.9 10.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_30 PF13604.6 EGC37961.1 - 0.14 11.8 0.0 0.42 10.3 0.0 1.8 1 1 0 1 1 1 0 AAA domain TP53IP5 PF15331.6 EGC37961.1 - 5.3 7.1 6.5 42 4.2 0.0 2.2 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 p450 PF00067.22 EGC37962.1 - 2.5e-46 158.4 0.0 1.7e-40 139.1 0.2 2.2 2 0 0 2 2 2 2 Cytochrome P450 RPA_C PF08784.11 EGC37962.1 - 0.036 14.7 0.0 0.088 13.5 0.0 1.6 1 0 0 1 1 1 0 Replication protein A C terminal DUF1084 PF06454.11 EGC37963.1 - 1.8e-16 60.4 21.0 2.3e-16 60.0 21.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) TMEM154 PF15102.6 EGC37964.1 - 6.2e-05 22.9 2.1 6.2e-05 22.9 2.1 1.9 2 0 0 2 2 2 1 TMEM154 protein family TIG PF01833.24 EGC37964.1 - 0.014 15.4 1.1 3.9 7.6 0.0 2.7 1 1 2 3 3 3 0 IPT/TIG domain ABC2_membrane_3 PF12698.7 EGC37964.1 - 2.9 6.9 8.9 7.1 5.6 8.9 1.6 1 1 0 1 1 1 0 ABC-2 family transporter protein PARP PF00644.20 EGC37965.1 - 2.7e-63 213.1 0.6 4.2e-63 212.5 0.6 1.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.14 EGC37965.1 - 1.4e-33 115.9 2.1 1.4e-33 115.9 2.1 1.6 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.15 EGC37965.1 - 3.3e-18 65.5 0.5 9.3e-18 64.1 0.5 1.8 1 0 0 1 1 1 1 WGR domain Ank_4 PF13637.6 EGC37966.1 - 6.5e-27 93.6 0.9 2.6e-06 27.9 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC37966.1 - 1.4e-24 86.5 0.9 7.7e-10 39.2 0.3 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.30 EGC37966.1 - 5.4e-20 70.9 3.0 0.004 17.5 0.0 6.2 6 0 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.6 EGC37966.1 - 1.6e-15 56.9 1.6 0.0024 18.1 0.1 5.2 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC37966.1 - 7.2e-15 53.6 6.3 0.055 14.0 0.0 6.8 6 2 0 6 6 6 3 Ankyrin repeat IBR PF01485.21 EGC37967.1 - 0.37 11.0 16.2 6.5 7.1 12.1 2.9 2 1 0 2 2 2 0 IBR domain, a half RING-finger domain zf-Di19 PF05605.12 EGC37967.1 - 6.6 7.1 12.4 1.1 9.6 0.3 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding RsgA_GTPase PF03193.16 EGC37968.1 - 0.00047 20.1 0.0 0.00078 19.4 0.0 1.4 1 0 0 1 1 1 1 RsgA GTPase ABC_tran PF00005.27 EGC37968.1 - 0.00089 19.8 0.4 0.0016 18.9 0.2 1.7 1 1 0 1 1 1 1 ABC transporter MMR_HSR1 PF01926.23 EGC37968.1 - 0.0011 19.0 0.5 0.0026 17.8 0.5 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.6 EGC37968.1 - 0.0018 18.0 0.1 0.0018 18.0 0.1 2.0 2 2 0 2 2 2 1 P-loop containing region of AAA domain Arf PF00025.21 EGC37968.1 - 0.003 17.0 0.1 0.0072 15.8 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family AAA_18 PF13238.6 EGC37968.1 - 0.0045 17.5 0.0 0.27 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.22 EGC37968.1 - 0.015 15.7 0.2 0.69 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase AAA_23 PF13476.6 EGC37968.1 - 0.017 15.6 0.9 0.033 14.7 0.5 1.6 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC37968.1 - 0.018 14.3 0.0 0.037 13.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_16 PF13191.6 EGC37968.1 - 0.025 15.0 0.0 0.05 14.0 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain IIGP PF05049.13 EGC37968.1 - 0.025 13.7 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) FtsK_SpoIIIE PF01580.18 EGC37968.1 - 0.026 13.9 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family T2SSE PF00437.20 EGC37968.1 - 0.03 13.4 0.0 0.038 13.1 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_PrkA PF08298.11 EGC37968.1 - 0.034 13.1 0.0 0.043 12.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain AAA_22 PF13401.6 EGC37968.1 - 0.038 14.3 0.0 0.1 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain Roc PF08477.13 EGC37968.1 - 0.039 14.2 0.1 0.084 13.1 0.1 1.8 1 1 0 1 1 1 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGC37968.1 - 0.048 13.7 0.0 0.098 12.7 0.0 1.5 1 0 0 1 1 1 0 Dynamin family TsaE PF02367.17 EGC37968.1 - 0.057 13.4 0.1 0.12 12.4 0.0 1.5 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE DUF87 PF01935.17 EGC37968.1 - 0.066 13.3 0.8 0.18 11.9 0.1 1.9 1 1 1 2 2 2 0 Helicase HerA, central domain PPV_E1_C PF00519.17 EGC37968.1 - 0.066 12.0 0.0 0.081 11.7 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase DLIC PF05783.11 EGC37968.1 - 0.072 11.9 0.1 0.33 9.7 0.0 1.9 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) Sigma54_activat PF00158.26 EGC37968.1 - 0.095 12.4 0.0 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain cobW PF02492.19 EGC37968.1 - 0.14 11.7 0.6 0.29 10.7 0.6 1.6 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain NACHT PF05729.12 EGC37968.1 - 0.2 11.6 0.2 0.39 10.6 0.0 1.6 2 0 0 2 2 1 0 NACHT domain AAA_28 PF13521.6 EGC37968.1 - 0.23 11.7 0.1 4 7.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain Rhodanese PF00581.20 EGC37969.1 - 1.5e-27 96.2 0.0 3e-13 50.2 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain RRM_1 PF00076.22 EGC37970.1 - 4.2e-20 71.3 0.1 6.5e-20 70.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC37970.1 - 2.5e-05 23.9 0.9 3.3e-05 23.5 0.6 1.4 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC37970.1 - 0.11 12.4 0.0 0.22 11.4 0.0 1.4 1 1 0 1 1 1 0 Occluded RNA-recognition motif RhoGAP PF00620.27 EGC37971.1 - 1.1e-39 135.7 0.4 3.7e-39 134.0 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain C2 PF00168.30 EGC37971.1 - 8.6e-20 71.0 0.0 2.2e-19 69.6 0.0 1.7 2 0 0 2 2 2 1 C2 domain PH PF00169.29 EGC37971.1 - 8.5e-10 39.1 1.5 8.5e-10 39.1 1.5 2.8 3 0 0 3 3 3 1 PH domain PH_3 PF14593.6 EGC37971.1 - 0.00022 21.3 0.6 0.00059 19.9 0.6 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.6 EGC37971.1 - 0.00029 21.2 0.0 0.00088 19.6 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PCI PF01399.27 EGC37972.1 - 5.4e-17 62.2 0.5 2.2e-16 60.2 0.5 2.2 1 1 0 1 1 1 1 PCI domain TPR_1 PF00515.28 EGC37972.1 - 0.01 15.6 3.0 0.021 14.7 0.3 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RPA_C PF08784.11 EGC37972.1 - 0.1 13.3 0.0 0.26 12.0 0.0 1.8 1 0 0 1 1 1 0 Replication protein A C terminal HTH_24 PF13412.6 EGC37972.1 - 0.14 11.8 0.0 0.33 10.5 0.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DASH_Dam1 PF08653.10 EGC37972.1 - 0.16 11.8 5.7 1 9.2 0.5 3.5 3 1 1 4 4 4 0 DASH complex subunit Dam1 GFA PF04828.14 EGC37973.1 - 0.023 15.0 0.1 0.023 15.0 0.1 1.6 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme ABC2_membrane_3 PF12698.7 EGC37974.1 - 0.008 15.3 7.0 0.011 14.9 7.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ALAD PF00490.21 EGC37974.1 - 0.045 12.9 0.7 0.41 9.8 0.7 2.0 1 1 0 1 1 1 0 Delta-aminolevulinic acid dehydratase Acyltransferase PF01553.21 EGC37975.1 - 7.5e-05 22.4 0.0 0.00013 21.6 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGC37975.1 - 0.074 13.2 4.2 0.13 12.4 0.6 2.5 2 0 0 2 2 2 0 Acyltransferase C-terminus Sigma_reg_N PF13800.6 EGC37975.1 - 0.85 9.9 7.9 4.2 7.7 2.2 2.6 1 1 1 2 2 2 0 Sigma factor regulator N-terminal TPPK_C PF12555.8 EGC37975.1 - 7.5 6.7 9.5 0.37 10.9 3.8 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal ubiquitin PF00240.23 EGC37976.1 - 2.9e-07 30.1 0.3 8.8e-07 28.6 0.3 1.9 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.8 EGC37976.1 - 0.01 16.3 0.2 0.047 14.2 0.2 2.2 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 AT_hook PF02178.19 EGC37976.1 - 0.34 10.9 2.8 0.81 9.8 2.8 1.6 1 0 0 1 1 1 0 AT hook motif Nodulin_late PF07127.11 EGC37978.1 - 4.1 7.8 7.1 5 7.5 0.0 3.1 3 0 0 3 3 3 0 Late nodulin protein Ank_5 PF13857.6 EGC37979.1 - 0.0052 17.1 0.0 0.1 13.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC37979.1 - 0.015 15.9 0.0 0.068 13.8 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC37979.1 - 0.14 12.8 0.0 11 7.0 0.0 3.4 2 0 0 2 2 2 0 Ankyrin repeat Torus PF16131.5 EGC37980.1 - 3.2e-28 98.6 2.4 3.2e-28 98.6 2.4 3.6 3 1 0 3 3 2 1 Torus domain RRM_1 PF00076.22 EGC37980.1 - 6.7e-07 29.0 0.0 1.4e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) EcoRII-N PF09217.10 EGC37980.1 - 0.00061 19.6 0.7 0.00061 19.6 0.7 1.8 2 0 0 2 2 2 1 Restriction endonuclease EcoRII, N-terminal zf_CCCH_4 PF18345.1 EGC37980.1 - 0.0078 16.2 5.9 0.019 15.0 5.9 1.7 1 0 0 1 1 1 1 Zinc finger domain RNA_polI_A34 PF08208.11 EGC37980.1 - 0.012 15.8 13.4 0.023 14.8 13.4 1.5 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 zf-CCCH PF00642.24 EGC37980.1 - 0.055 13.4 4.6 0.11 12.4 4.6 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RNA_pol_Rpc4 PF05132.14 EGC37980.1 - 0.062 13.7 7.4 0.29 11.5 8.2 1.9 2 0 0 2 2 2 0 RNA polymerase III RPC4 Nup35_RRM_2 PF14605.6 EGC37980.1 - 0.15 12.1 0.1 0.35 10.9 0.1 1.5 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif GEMIN8 PF15348.6 EGC37980.1 - 0.41 10.9 24.3 1 9.6 24.3 1.6 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DDHD PF02862.17 EGC37980.1 - 0.44 10.7 9.5 0.97 9.5 9.5 1.6 1 0 0 1 1 1 0 DDHD domain DUF3007 PF11460.8 EGC37980.1 - 1.1 9.6 3.6 12 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Nop14 PF04147.12 EGC37980.1 - 1.8 6.7 33.7 2.4 6.3 33.7 1.2 1 0 0 1 1 1 0 Nop14-like family zf-CCCH_4 PF18044.1 EGC37980.1 - 2.7 7.9 7.9 6.4 6.7 7.9 1.6 1 0 0 1 1 1 0 CCCH-type zinc finger G-alpha PF00503.20 EGC37981.1 - 2.8e-91 306.4 3.0 3.6e-91 306.0 3.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC37981.1 - 5.2e-14 52.1 0.0 1.3e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Roc PF08477.13 EGC37981.1 - 2.5e-05 24.5 0.0 0.27 11.5 0.0 2.6 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGC37981.1 - 0.00077 18.9 0.1 0.16 11.3 0.0 2.4 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC37981.1 - 0.0077 16.3 0.1 2.2 8.4 0.0 2.7 2 1 0 2 2 2 2 50S ribosome-binding GTPase Ribosomal_S13_N PF08069.12 EGC37982.1 - 7.1e-28 96.4 1.0 9.1e-28 96.1 0.1 1.7 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.22 EGC37982.1 - 5.1e-11 42.6 0.1 6.5e-11 42.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein S15 HicB PF05534.12 EGC37982.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 HicB family TUG-UBL1 PF11470.8 EGC37983.1 - 7.3e-17 61.4 0.0 5.2e-16 58.6 0.0 2.6 2 0 0 2 2 2 1 TUG ubiquitin-like domain UBX PF00789.20 EGC37983.1 - 3e-06 27.3 0.7 0.093 12.9 0.2 2.7 2 0 0 2 2 2 2 UBX domain Mei5_like PF17021.5 EGC37983.1 - 0.042 13.9 0.1 0.042 13.9 0.1 2.9 3 0 0 3 3 3 0 Putative double-strand recombination repair-like DUF3670 PF12419.8 EGC37983.1 - 0.11 12.4 0.0 0.2 11.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein Atrophin-1 PF03154.15 EGC37983.1 - 0.18 10.1 30.1 0.13 10.5 2.8 2.4 2 0 0 2 2 2 0 Atrophin-1 family SHMT PF00464.19 EGC37984.1 - 2.1e-189 629.2 0.0 2.4e-189 629.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Macro PF01661.21 EGC37984.1 - 0.0018 18.3 0.0 0.011 15.8 0.0 2.2 2 0 0 2 2 2 1 Macro domain Aminotran_5 PF00266.19 EGC37984.1 - 0.011 14.7 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 0 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGC37984.1 - 0.066 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.16 EGC37985.1 - 1.6e-27 96.4 30.9 4.6e-27 94.9 31.0 1.7 1 1 1 2 2 2 1 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC37985.1 - 6.2e-09 35.2 4.4 6.2e-09 35.2 4.4 2.2 1 1 0 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.13 EGC37985.1 - 0.0014 17.2 4.9 0.41 9.0 1.8 2.3 2 0 0 2 2 2 2 Transmembrane secretion effector Oxysterol_BP PF01237.18 EGC37986.1 - 5.5e-49 167.0 0.9 4.2e-48 164.1 0.9 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein zf-B_box PF00643.24 EGC37987.1 - 2.4e-06 27.6 3.8 3.4e-06 27.1 3.8 1.2 1 0 0 1 1 1 1 B-box zinc finger DASH_Duo1 PF08651.10 EGC37987.1 - 0.023 14.5 3.9 0.11 12.3 1.0 2.1 2 0 0 2 2 2 0 DASH complex subunit Duo1 Sec20 PF03908.13 EGC37987.1 - 0.036 14.0 0.6 0.061 13.2 0.6 1.4 1 0 0 1 1 1 0 Sec20 zf-UBR PF02207.20 EGC37987.1 - 0.064 13.4 1.9 0.11 12.6 1.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Organ_specific PF10950.8 EGC37987.1 - 0.13 13.0 5.0 0.21 12.3 5.0 1.4 1 0 0 1 1 1 0 Organ specific protein Syntaxin-6_N PF09177.11 EGC37988.1 - 4.3e-24 84.9 0.9 2.2e-23 82.7 0.0 2.3 2 1 0 2 2 2 1 Syntaxin 6, N-terminal Use1 PF09753.9 EGC37988.1 - 1.2e-05 25.2 4.3 1.5e-05 24.9 4.3 1.2 1 0 0 1 1 1 1 Membrane fusion protein Use1 SNARE PF05739.19 EGC37988.1 - 3.3e-05 23.8 0.2 3.3e-05 23.8 0.2 1.9 2 0 0 2 2 2 1 SNARE domain APG17 PF04108.12 EGC37988.1 - 0.00014 21.1 2.2 0.0015 17.7 0.0 2.2 1 1 0 2 2 2 1 Autophagy protein Apg17 Phage_holin_2_1 PF04971.12 EGC37988.1 - 0.052 13.6 0.2 0.12 12.4 0.2 1.6 1 0 0 1 1 1 0 Bacteriophage P21 holin S CREPT PF16566.5 EGC37988.1 - 0.074 13.2 6.7 0.26 11.5 5.5 2.4 2 1 1 3 3 3 0 Cell-cycle alteration and expression-elevated protein in tumour Sec8_exocyst PF04048.14 EGC37988.1 - 0.083 12.8 4.5 0.22 11.4 1.6 2.4 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain DUF745 PF05335.13 EGC37988.1 - 0.19 11.5 0.7 1.2 8.9 0.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF745) Enkurin PF13864.6 EGC37988.1 - 0.19 12.2 0.1 0.19 12.2 0.1 2.9 2 1 1 3 3 3 0 Calmodulin-binding Prominin PF05478.11 EGC37988.1 - 0.21 9.5 4.6 4 5.3 1.8 2.1 2 0 0 2 2 2 0 Prominin Cnn_1N PF07989.11 EGC37988.1 - 0.26 11.4 5.9 0.82 9.9 1.9 2.8 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 FadA PF09403.10 EGC37988.1 - 0.29 11.6 5.0 9.5 6.8 0.3 2.7 2 0 0 2 2 2 0 Adhesion protein FadA VSG_B PF13206.6 EGC37989.1 - 0.12 11.6 5.9 0.019 14.2 1.9 1.7 2 0 0 2 2 2 0 Trypanosomal VSG domain TFIIA PF03153.13 EGC37989.1 - 1.7 8.5 26.1 2.6 8.0 26.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PI3K_1B_p101 PF10486.9 EGC37989.1 - 8.5 4.0 12.6 12 3.6 12.6 1.3 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Metallophos PF00149.28 EGC37990.1 - 1.2e-35 123.9 0.9 1.7e-35 123.4 0.9 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase STPPase_N PF16891.5 EGC37990.1 - 0.0024 18.3 0.1 0.0049 17.3 0.1 1.4 1 0 0 1 1 1 1 Serine-threonine protein phosphatase N-terminal domain Metallophos_2 PF12850.7 EGC37990.1 - 0.11 12.6 0.0 0.18 12.0 0.0 1.5 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain Glyco_hydro_65N PF03636.15 EGC37990.1 - 0.17 11.5 0.0 0.25 10.9 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain Clathrin PF00637.20 EGC37991.1 - 2e-20 73.1 20.8 8.5e-15 54.9 4.3 3.3 3 1 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.8 EGC37991.1 - 1.8e-17 63.3 2.1 4.3e-17 62.0 0.8 2.5 3 0 0 3 3 2 1 Vacuolar protein sorting protein 11 C terminal zf-C3H2C3 PF17122.5 EGC37991.1 - 1.3e-05 25.1 7.9 2.7e-05 24.1 7.9 1.6 1 0 0 1 1 1 1 Zinc-finger zf-C3HC4_2 PF13923.6 EGC37991.1 - 0.00014 21.6 9.1 0.00033 20.4 9.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC37991.1 - 0.00099 19.4 9.2 0.00099 19.4 9.2 1.8 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.6 EGC37991.1 - 0.0045 16.9 7.2 0.011 15.7 7.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain TPR_11 PF13414.6 EGC37991.1 - 0.0051 16.5 1.0 0.021 14.5 1.0 2.1 1 0 0 1 1 1 1 TPR repeat zf-rbx1 PF12678.7 EGC37991.1 - 0.0081 16.4 7.7 0.02 15.2 7.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC37991.1 - 0.019 14.8 0.8 0.047 13.6 0.8 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGC37991.1 - 0.051 13.6 7.2 0.14 12.2 7.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Aminotran_3 PF00202.21 EGC37991.1 - 0.12 11.0 0.0 0.26 9.9 0.0 1.4 1 0 0 1 1 1 0 Aminotransferase class-III zf-ANAPC11 PF12861.7 EGC37991.1 - 0.13 12.3 1.2 0.47 10.5 1.2 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.22 EGC37991.1 - 0.3 11.0 3.1 0.86 9.5 3.1 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4 PF00097.25 EGC37991.1 - 1.1 9.1 8.8 3.2 7.7 8.8 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC37991.1 - 1.1 9.1 5.6 3.2 7.7 5.6 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.17 EGC37991.1 - 3.7 7.9 8.2 1.5 9.1 1.3 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat Zn-ribbon_8 PF09723.10 EGC37991.1 - 5.5 7.2 5.4 12 6.2 2.4 2.6 2 0 0 2 2 2 0 Zinc ribbon domain CLU PF13236.6 EGC37992.1 - 1.5e-63 214.6 0.0 3.6e-63 213.3 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC37992.1 - 2.2e-05 24.6 0.1 2.2e-05 24.6 0.1 3.6 3 0 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 Peptidase_S9_N PF02897.15 EGC37993.1 - 1.9e-113 379.4 6.8 2.3e-113 379.1 6.8 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.21 EGC37993.1 - 2.7e-61 206.7 0.0 4.5e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Acetyltransf_19 PF18015.1 EGC37993.1 - 0.027 14.7 0.7 0.1 12.8 0.3 2.2 3 0 0 3 3 3 0 Acetyltransferase (GNAT) domain BAAT_C PF08840.11 EGC37993.1 - 0.047 13.6 0.0 0.24 11.3 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_3 PF07859.13 EGC37993.1 - 0.2 11.5 0.0 1.9 8.3 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold PARP PF00644.20 EGC37994.1 - 6.9e-21 74.7 0.1 6.9e-21 74.7 0.1 2.8 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.20 EGC37994.1 - 9.8e-18 64.5 8.6 3.5e-08 33.9 1.0 3.4 3 0 0 3 3 3 2 WWE domain Rab5-bind PF09311.11 EGC37994.1 - 0.011 15.1 3.8 0.011 15.1 3.8 1.5 2 0 0 2 2 2 0 Rabaptin-like protein zf-C2HCIx2C PF10782.9 EGC37995.1 - 0.027 14.4 0.0 0.11 12.4 0.0 2.0 1 0 0 1 1 1 0 Zinc-finger ETRAMP PF09716.10 EGC37995.1 - 0.14 12.3 4.5 3.6 7.7 0.3 2.7 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4449 PF14613.6 EGC37996.1 - 0.019 15.1 5.5 0.15 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4449) Exonuc_VII_L PF02601.15 EGC37996.1 - 0.2 11.2 3.8 0.25 10.9 3.8 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit YlqD PF11068.8 EGC37996.1 - 1.1 9.7 11.7 6.4 7.2 4.3 2.1 2 0 0 2 2 2 0 YlqD protein PRP1_N PF06424.12 EGC37996.1 - 1.8 9.0 9.9 0.37 11.2 1.9 2.2 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal EMC3_TMCO1 PF01956.16 EGC37996.1 - 2.4 7.8 7.3 4.3 7.0 7.3 1.3 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Presenilin PF01080.17 EGC37996.1 - 4.5 5.9 6.3 5.7 5.6 6.3 1.1 1 0 0 1 1 1 0 Presenilin Porph_ging PF09697.10 EGC37996.1 - 9.2 6.9 7.6 5.3 7.7 1.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (Porph_ging) LMBR1 PF04791.16 EGC37996.1 - 9.7 5.0 7.6 12 4.7 7.6 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Pkinase PF00069.25 EGC37997.1 - 5.8e-66 222.5 0.0 7.8e-66 222.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC37997.1 - 4.1e-27 95.1 0.0 5.9e-27 94.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.24 EGC37997.1 - 1.1e-05 26.0 1.1 2.6e-05 24.9 0.1 2.1 2 0 0 2 2 2 1 Protein kinase C terminal domain C2 PF00168.30 EGC37997.1 - 0.00012 22.4 0.0 0.0006 20.1 0.0 2.0 1 1 0 1 1 1 1 C2 domain Kinase-like PF14531.6 EGC37997.1 - 0.013 14.9 0.0 0.02 14.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.14 EGC37997.1 - 0.019 14.3 0.0 0.037 13.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC37997.1 - 0.028 13.3 0.0 0.047 12.6 0.0 1.3 1 0 0 1 1 1 0 Haspin like kinase domain LRR_6 PF13516.6 EGC37998.1 - 1.7e-07 30.8 21.7 0.089 12.9 0.0 9.0 10 0 0 10 10 10 3 Leucine Rich repeat PDZ_1 PF12812.7 EGC37998.1 - 0.11 12.6 0.0 0.44 10.6 0.0 2.0 1 0 0 1 1 1 0 PDZ-like domain Mrpl_C PF18502.1 EGC37998.1 - 0.31 11.3 5.0 1.1 9.6 5.0 1.9 1 0 0 1 1 1 0 54S ribosomal protein L8 C-terminal domain FNIP PF05725.12 EGC37999.1 - 2e-68 226.3 57.0 8.8e-15 54.6 2.3 8.3 6 3 3 9 9 9 8 FNIP Repeat Spidroin_MaSp PF11260.8 EGC37999.1 - 0.14 12.4 2.2 14 6.1 0.4 3.2 1 1 0 2 2 2 0 Major ampullate spidroin 1 and 2 FdhD-NarQ PF02634.15 EGC37999.1 - 0.18 11.5 0.0 28 4.3 0.0 3.2 2 1 0 2 2 2 0 FdhD/NarQ family Phospholip_B PF04916.13 EGC38000.1 - 6.5e-150 500.2 17.2 7.3e-150 500.0 17.2 1.0 1 0 0 1 1 1 1 Phospholipase B zf-C3HC PF07967.13 EGC38001.1 - 1.2e-33 116.0 0.1 1.2e-33 116.0 0.1 3.2 3 0 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.10 EGC38001.1 - 5.8e-11 42.4 17.3 1.7e-05 24.9 0.0 4.8 5 0 0 5 5 5 3 Rsm1-like RasGEF PF00617.19 EGC38002.1 - 2.1e-58 197.4 0.9 2.1e-58 197.4 0.9 3.0 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC38002.1 - 2.2e-27 95.4 4.0 7.5e-27 93.6 1.2 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif LisH_TPL PF17814.1 EGC38002.1 - 0.0027 17.3 0.4 0.011 15.4 0.4 2.1 1 0 0 1 1 1 1 LisH-like dimerisation domain LisH PF08513.11 EGC38002.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.6 1 0 0 1 1 1 0 LisH Eaf7 PF07904.13 EGC38002.1 - 2.8 8.4 5.9 46 4.4 0.1 3.0 2 0 0 2 2 2 0 Chromatin modification-related protein EAF7 FNIP PF05725.12 EGC38004.1 - 5e-217 702.0 100.7 2.9e-15 56.1 0.2 14.4 4 3 17 21 21 21 20 FNIP Repeat Phage_min_tail PF05939.13 EGC38004.1 - 1.8e-06 28.3 0.0 42 4.6 0.0 8.7 7 3 4 11 11 11 0 Phage minor tail protein HTH_ABP1_N PF18107.1 EGC38004.1 - 0.00075 19.2 0.0 94 2.8 0.0 7.9 12 0 0 12 12 12 0 Fission yeast centromere protein N-terminal domain Bclx_interact PF08945.10 EGC38004.1 - 0.12 12.2 1.8 75 3.2 0.0 4.8 5 0 0 5 5 5 0 Bcl-x interacting, BH3 domain DUF3215 PF11503.8 EGC38004.1 - 0.14 12.0 9.3 29 4.6 0.0 8.3 9 1 1 10 10 10 0 Protein of unknown function (DUF3215) LRR_1 PF00560.33 EGC38004.1 - 8.7 7.3 10.4 2.7e+02 2.8 0.0 7.4 6 3 0 6 6 6 0 Leucine Rich Repeat Noc2 PF03715.13 EGC38005.1 - 4.9e-109 364.2 6.4 4.9e-109 364.2 6.4 2.1 3 0 0 3 3 3 1 Noc2p family Nop14 PF04147.12 EGC38005.1 - 2.4e-06 26.1 2.9 2.4e-06 26.1 2.9 4.1 2 2 2 4 4 4 1 Nop14-like family Metallophos PF00149.28 EGC38006.1 - 2.1e-10 41.4 0.0 9.1e-10 39.4 0.0 2.0 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.7 EGC38006.1 - 0.0018 18.5 0.0 0.0047 17.1 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain DUF4271 PF14093.6 EGC38006.1 - 0.27 11.1 27.0 0.77 9.6 21.6 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Rhomboid PF01694.22 EGC38006.1 - 0.36 10.8 8.9 0.1 12.6 5.4 1.8 1 1 1 2 2 2 0 Rhomboid family RRM_1 PF00076.22 EGC38007.1 - 3.1e-61 203.1 0.0 6.9e-23 80.3 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC38007.1 - 4.1e-13 49.0 0.1 0.00025 20.7 0.5 3.2 2 1 1 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC38007.1 - 1.7e-06 28.0 1.4 0.0067 16.4 0.1 2.7 2 1 0 2 2 2 2 RNA binding motif RRM_occluded PF16842.5 EGC38007.1 - 0.00019 21.2 0.0 0.14 12.0 0.0 3.1 4 0 0 4 4 4 2 Occluded RNA-recognition motif RRM_7 PF16367.5 EGC38007.1 - 0.003 17.6 0.3 1.1 9.4 0.0 3.6 3 2 0 3 3 3 1 RNA recognition motif PSP1 PF04468.12 EGC38007.1 - 0.0038 17.5 0.2 0.039 14.2 0.3 2.1 2 0 0 2 2 2 1 PSP1 C-terminal conserved region DUF4523 PF15023.6 EGC38007.1 - 0.26 11.1 1.6 11 5.8 0.0 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4523) SUIM_assoc PF16619.5 EGC38007.1 - 2.6 8.2 10.9 0.14 12.3 2.9 2.2 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 Ribosomal_L32p PF01783.23 EGC38008.1 - 0.041 14.1 4.7 0.067 13.5 4.7 1.4 1 0 0 1 1 1 0 Ribosomal L32p protein family Peptidase_C1 PF00112.23 EGC38010.1 - 8.7e-73 245.0 17.6 8.3e-71 238.5 17.6 2.3 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC38010.1 - 7.5e-14 51.9 3.5 1.3e-13 51.2 3.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC38010.1 - 0.00062 18.7 3.9 0.16 10.8 1.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family Presenilin PF01080.17 EGC38010.1 - 2.6 6.7 4.4 4.1 6.1 4.4 1.3 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.7 EGC38010.1 - 3.6 5.6 5.9 5.6 5.0 5.9 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein SPX PF03105.19 EGC38010.1 - 6.6 6.5 16.6 9.7 6.0 16.6 1.3 1 0 0 1 1 1 0 SPX domain Apt1 PF10351.9 EGC38010.1 - 9.1 5.0 14.4 13 4.5 14.4 1.2 1 0 0 1 1 1 0 Golgi-body localisation protein domain Polbeta PF18765.1 EGC38011.1 - 0.02 14.9 0.4 0.072 13.2 0.2 2.1 1 1 0 1 1 1 0 Polymerase beta, Nucleotidyltransferase Curto_V3 PF07436.11 EGC38011.1 - 0.05 14.0 2.6 0.12 12.8 0.2 3.1 2 0 0 2 2 2 0 Curtovirus V3 protein NIF PF03031.18 EGC38012.1 - 1e-54 184.6 0.3 1e-54 184.6 0.3 1.8 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Synaptobrevin PF00957.21 EGC38013.1 - 1.7e-28 98.3 3.5 1.8e-28 98.1 3.5 1.0 1 0 0 1 1 1 1 Synaptobrevin RIFIN PF02009.16 EGC38013.1 - 8.5e-05 22.6 0.1 9.2e-05 22.5 0.1 1.0 1 0 0 1 1 1 1 Rifin Orf78 PF06024.12 EGC38013.1 - 0.0016 18.7 0.8 0.0018 18.6 0.8 1.3 1 1 0 1 1 1 1 Orf78 (ac78) Sec5 PF15469.6 EGC38013.1 - 0.026 14.3 0.2 0.029 14.2 0.2 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 UPF0258 PF06789.12 EGC38013.1 - 0.056 13.6 1.7 0.074 13.2 1.7 1.3 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) TraD_N PF12615.8 EGC38013.1 - 0.056 14.2 0.1 0.065 14.0 0.1 1.2 1 0 0 1 1 1 0 F sex factor protein N terminal MAPEG PF01124.18 EGC38014.1 - 0.011 15.6 0.0 0.017 15.0 0.0 1.2 1 0 0 1 1 1 0 MAPEG family Rad51 PF08423.11 EGC38015.1 - 3.5e-09 36.3 0.0 1.9e-06 27.3 0.0 2.3 2 0 0 2 2 2 2 Rad51 ATPase PF06745.13 EGC38015.1 - 0.0028 17.0 0.2 0.0073 15.7 0.0 1.7 2 0 0 2 2 2 1 KaiC PRK PF00485.18 EGC38015.1 - 0.0073 16.1 0.0 0.018 14.8 0.0 1.8 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGC38015.1 - 0.012 16.2 1.6 0.021 15.4 1.4 1.6 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGC38015.1 - 0.021 14.4 0.0 1.1 8.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain RecA PF00154.21 EGC38015.1 - 0.092 12.2 0.1 0.28 10.6 0.0 1.8 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_24 PF13479.6 EGC38015.1 - 0.46 10.2 2.5 5.1 6.8 2.2 2.4 1 1 0 1 1 1 0 AAA domain Secretin_N_2 PF07655.13 EGC38015.1 - 2.1 8.9 14.3 11 6.6 10.8 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain MS_channel PF00924.18 EGC38017.1 - 1.7e-24 86.6 3.6 3.9e-24 85.3 3.6 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel TctB PF07331.11 EGC38017.1 - 0.0075 16.5 0.2 0.0075 16.5 0.2 2.8 3 0 0 3 3 3 1 Tripartite tricarboxylate transporter TctB family PBP1_TM PF14812.6 EGC38017.1 - 0.011 16.1 0.8 0.029 14.7 0.8 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Orf78 PF06024.12 EGC38017.1 - 0.42 10.9 0.1 0.42 10.9 0.1 3.0 4 0 0 4 4 4 0 Orf78 (ac78) U1snRNP70_N PF12220.8 EGC38017.1 - 0.85 10.3 8.0 10 6.8 0.8 2.6 2 0 0 2 2 2 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal DUF2207 PF09972.9 EGC38017.1 - 1.5 7.5 14.0 2.2 6.9 6.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) FtsL PF04999.13 EGC38017.1 - 5.7 7.0 8.1 0.22 11.5 1.4 2.1 2 0 0 2 2 2 0 Cell division protein FtsL zf-HIT PF04438.16 EGC38018.1 - 1.7e-07 31.0 8.0 2.7e-07 30.3 8.0 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGC38018.1 - 0.039 14.1 5.5 0.069 13.3 5.5 1.3 1 0 0 1 1 1 0 MYND finger Hydrolase_4 PF12146.8 EGC38019.1 - 2.6e-56 190.5 0.0 3.7e-56 190.1 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_1 PF00561.20 EGC38019.1 - 2.5e-08 33.9 0.2 7e-06 25.9 0.0 2.9 2 1 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.7 EGC38019.1 - 6.3e-07 30.2 0.0 8.6e-07 29.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.16 EGC38019.1 - 3.4e-06 27.0 0.2 0.0017 18.2 0.1 2.9 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Peptidase_S9 PF00326.21 EGC38019.1 - 0.0052 16.3 0.0 0.031 13.7 0.0 2.2 3 0 0 3 3 3 1 Prolyl oligopeptidase family AXE1 PF05448.12 EGC38019.1 - 0.007 15.1 0.0 1.3 7.6 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Dehalogenase PF13486.6 EGC38019.1 - 0.014 14.8 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 Reductive dehalogenase subunit Peptidase_S15 PF02129.18 EGC38019.1 - 0.015 14.9 0.0 1.7 8.2 0.0 2.3 2 1 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.13 EGC38019.1 - 0.047 13.4 0.0 0.24 11.0 0.0 2.1 2 0 0 2 2 2 0 Serine hydrolase (FSH1) AAA PF00004.29 EGC38020.1 - 1.6e-55 187.1 0.0 3.1e-40 137.7 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC38020.1 - 4.2e-10 40.3 0.1 0.0013 19.1 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.6 EGC38020.1 - 2.1e-09 37.8 1.6 0.0057 16.9 0.2 4.1 2 2 1 3 3 3 2 AAA domain AAA_5 PF07728.14 EGC38020.1 - 1.8e-08 34.5 0.0 0.00098 19.1 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_lid_3 PF17862.1 EGC38020.1 - 8.3e-08 31.9 0.0 1.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 AAA+ lid domain AAA_2 PF07724.14 EGC38020.1 - 1e-07 32.2 0.0 6.4e-06 26.4 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.22 EGC38020.1 - 1e-07 32.3 0.0 0.0065 16.8 0.0 3.1 2 0 0 2 2 2 2 RNA helicase RuvB_N PF05496.12 EGC38020.1 - 1e-07 31.8 0.0 0.016 15.0 0.1 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGC38020.1 - 1.1e-07 32.1 0.0 0.013 15.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.6 EGC38020.1 - 2.2e-07 31.0 0.0 0.00063 19.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.6 EGC38020.1 - 3.4e-07 30.9 0.0 0.098 13.2 0.0 3.5 3 1 1 4 4 3 2 AAA domain Mg_chelatase PF01078.21 EGC38020.1 - 4.7e-06 26.1 0.4 0.011 15.1 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI TsaE PF02367.17 EGC38020.1 - 1.2e-05 25.3 0.0 0.059 13.4 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Sigma54_activat PF00158.26 EGC38020.1 - 2.6e-05 24.0 0.1 0.13 11.9 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain ABC_tran PF00005.27 EGC38020.1 - 2.6e-05 24.7 0.1 0.46 11.0 0.1 2.7 2 1 0 2 2 2 2 ABC transporter NB-ARC PF00931.22 EGC38020.1 - 9.4e-05 21.7 0.3 0.31 10.2 0.1 2.3 2 0 0 2 2 2 2 NB-ARC domain AAA_7 PF12775.7 EGC38020.1 - 0.00015 21.4 0.3 0.06 12.8 0.1 2.6 2 0 0 2 2 2 1 P-loop containing dynein motor region AAA_3 PF07726.11 EGC38020.1 - 0.00015 21.6 0.0 0.86 9.5 0.0 2.9 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGC38020.1 - 0.00016 21.5 0.0 0.75 9.5 0.0 2.7 2 0 0 2 2 2 2 AAA domain TIP49 PF06068.13 EGC38020.1 - 0.00016 21.0 0.0 0.12 11.5 0.0 2.4 2 0 0 2 2 2 2 TIP49 P-loop domain Viral_helicase1 PF01443.18 EGC38020.1 - 0.00019 21.3 0.0 0.053 13.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase NACHT PF05729.12 EGC38020.1 - 0.00019 21.4 4.3 0.37 10.7 0.1 3.8 4 0 0 4 4 4 2 NACHT domain IstB_IS21 PF01695.17 EGC38020.1 - 0.0002 21.1 0.0 0.35 10.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_11 PF13086.6 EGC38020.1 - 0.00023 21.1 0.0 0.062 13.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain ATPase_2 PF01637.18 EGC38020.1 - 0.00026 21.0 0.3 3 7.7 0.0 4.2 2 2 2 4 4 4 1 ATPase domain predominantly from Archaea ATPase PF06745.13 EGC38020.1 - 0.00051 19.5 0.2 0.073 12.4 0.1 2.6 2 0 0 2 2 2 1 KaiC CDC48_2 PF02933.17 EGC38020.1 - 0.00077 19.2 0.2 0.01 15.6 0.0 2.5 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 AAA_25 PF13481.6 EGC38020.1 - 0.0014 18.3 0.8 2.2 7.8 0.1 3.1 3 0 0 3 3 3 1 AAA domain Parvo_NS1 PF01057.17 EGC38020.1 - 0.0023 17.0 0.0 1.1 8.3 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 Torsin PF06309.11 EGC38020.1 - 0.0033 17.5 0.1 2.6 8.2 0.0 2.5 2 0 0 2 2 2 1 Torsin DUF815 PF05673.13 EGC38020.1 - 0.0036 16.5 0.2 0.12 11.5 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF815) Zeta_toxin PF06414.12 EGC38020.1 - 0.0042 16.4 1.0 0.24 10.6 0.0 3.0 4 0 0 4 4 3 1 Zeta toxin Rad17 PF03215.15 EGC38020.1 - 0.0047 16.9 0.0 0.71 9.8 0.0 2.8 2 0 0 2 2 2 1 Rad17 P-loop domain TniB PF05621.11 EGC38020.1 - 0.0082 15.6 0.7 5.1 6.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial TniB protein AAA_30 PF13604.6 EGC38020.1 - 0.0096 15.7 0.4 0.31 10.7 0.1 2.5 3 0 0 3 3 2 1 AAA domain DUF2075 PF09848.9 EGC38020.1 - 0.013 14.7 0.1 0.98 8.6 0.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.6 EGC38020.1 - 0.016 15.3 0.0 2.7 8.1 0.0 2.7 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_28 PF13521.6 EGC38020.1 - 0.02 15.1 0.1 7.8 6.7 0.1 2.4 2 0 0 2 2 2 0 AAA domain CDC48_N PF02359.18 EGC38020.1 - 0.021 15.0 0.0 0.67 10.2 0.0 3.0 2 1 0 2 2 2 0 Cell division protein 48 (CDC48), N-terminal domain AAA_17 PF13207.6 EGC38020.1 - 0.027 14.9 0.0 8.1 6.9 0.0 2.8 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.6 EGC38020.1 - 0.031 14.6 0.2 0.58 10.5 0.0 2.7 3 0 0 3 3 2 0 AAA domain KTI12 PF08433.10 EGC38020.1 - 0.055 12.9 0.1 5.6 6.3 0.0 2.4 2 0 0 2 2 2 0 Chromatin associated protein KTI12 BsuBI_PstI_RE PF06616.11 EGC38020.1 - 0.076 12.3 0.1 0.3 10.4 0.0 2.0 3 0 0 3 3 1 0 BsuBI/PstI restriction endonuclease domain CPT PF07931.12 EGC38020.1 - 0.088 12.6 0.1 2.9 7.7 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein PhoH PF02562.16 EGC38020.1 - 0.091 12.2 0.1 3 7.2 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein DUF5432 PF17497.2 EGC38020.1 - 0.15 12.2 0.0 0.37 10.9 0.0 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5432) Hydin_ADK PF17213.3 EGC38020.1 - 0.21 11.9 0.2 12 6.1 0.0 2.4 2 0 0 2 2 2 0 Hydin Adenylate kinase-like domain DAP3 PF10236.9 EGC38020.1 - 0.25 10.5 1.2 5.9 6.0 0.1 2.5 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 AAA_29 PF13555.6 EGC38020.1 - 0.26 11.1 3.2 7.9 6.3 0.1 3.1 3 1 0 3 3 2 0 P-loop containing region of AAA domain Terpene_synth_C PF03936.16 EGC38021.1 - 4.1e-06 26.3 2.7 6.4e-06 25.7 2.7 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain ArAE_1_C PF11728.8 EGC38021.1 - 0.46 10.5 6.7 0.11 12.5 0.5 2.5 3 1 0 3 3 3 0 Putative aromatic acid exporter C-terminal domain DpnI_C PF17726.1 EGC38021.1 - 1.2 9.3 6.6 0.68 10.1 0.7 3.2 3 0 0 3 3 3 0 Dam-replacing HTH domain PP2C PF00481.21 EGC38022.1 - 0.037 13.6 0.1 1.5 8.4 0.0 2.6 2 1 0 2 2 2 0 Protein phosphatase 2C Amidohydro_1 PF01979.20 EGC38026.1 - 5.5e-70 236.4 0.0 7.6e-70 235.9 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.11 EGC38026.1 - 1.7e-11 44.2 0.0 6.9e-06 25.8 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family CALCOCO1 PF07888.11 EGC38028.1 - 6.9e-05 21.9 31.5 6.9e-05 21.9 31.5 3.2 1 1 2 3 3 3 2 Calcium binding and coiled-coil domain (CALCOCO1) like UVR PF02151.19 EGC38028.1 - 6.3 6.7 11.0 1 9.2 1.1 4.2 4 0 0 4 4 4 0 UvrB/uvrC motif Cyclin_N PF00134.23 EGC38029.1 - 3.7e-43 146.3 1.8 3.7e-43 146.3 1.8 2.0 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC38029.1 - 6.5e-34 116.6 1.6 1.3e-33 115.6 1.6 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain tRNA_NucTransf2 PF09249.11 EGC38029.1 - 0.081 13.2 0.0 0.22 11.8 0.0 1.7 1 0 0 1 1 1 0 tRNA nucleotidyltransferase, second domain ALMT PF11744.8 EGC38032.1 - 6.8e-40 137.3 8.5 6.8e-40 137.3 8.5 2.6 2 0 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.6 EGC38032.1 - 1.1e-14 54.7 13.3 1.1e-14 54.7 13.3 3.3 2 1 1 3 3 3 1 Fusaric acid resistance protein-like FUSC PF04632.12 EGC38032.1 - 2e-13 49.8 12.1 1.6e-12 46.8 0.6 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein family zf-RING_2 PF13639.6 EGC38033.1 - 0.00019 21.7 2.4 0.00019 21.7 2.4 2.3 2 0 0 2 2 2 1 Ring finger domain PHD PF00628.29 EGC38033.1 - 0.0019 18.0 0.8 0.0019 18.0 0.8 2.5 2 0 0 2 2 2 1 PHD-finger zf-RING_11 PF17123.5 EGC38033.1 - 0.0029 17.3 0.6 0.0065 16.2 0.6 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4 PF00097.25 EGC38033.1 - 0.0085 15.9 1.7 0.0085 15.9 1.7 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) PHD_4 PF16866.5 EGC38033.1 - 0.04 14.0 2.2 0.04 14.0 2.2 3.3 2 1 1 3 3 3 0 PHD-finger zf-ANAPC11 PF12861.7 EGC38033.1 - 0.051 13.6 4.3 0.37 10.9 4.3 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGC38033.1 - 1.8 8.6 12.5 0.037 14.0 5.1 2.2 2 1 0 2 2 2 0 RING-type zinc-finger VWA_2 PF13519.6 EGC38034.1 - 1.4e-09 38.6 3.0 1.9e-07 31.7 0.1 3.8 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.14 EGC38034.1 - 6.4e-06 25.7 0.1 0.0049 16.3 0.0 2.9 2 1 0 2 2 2 2 VWA domain containing CoxE-like protein F-box-like PF12937.7 EGC38034.1 - 2.5e-05 24.1 1.1 6.2e-05 22.8 1.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC38034.1 - 0.00044 20.0 1.3 0.0024 17.7 1.3 2.4 1 0 0 1 1 1 1 F-box domain SKICH PF17751.1 EGC38035.1 - 1.7e-15 57.4 1.0 2.5e-05 24.8 0.0 4.1 3 0 0 3 3 3 3 SKICH domain HECW_N PF16562.5 EGC38035.1 - 5e-08 32.8 0.2 0.012 15.4 0.0 3.8 3 0 0 3 3 3 2 N-terminal domain of E3 ubiquitin-protein ligase HECW1 and 2 CUE PF02845.16 EGC38035.1 - 0.007 16.1 0.2 4.4 7.1 0.0 2.6 2 0 0 2 2 2 2 CUE domain fn3_3 PF14686.6 EGC38035.1 - 0.051 13.4 0.2 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 Polysaccharide lyase family 4, domain II fn3_PAP PF17808.1 EGC38035.1 - 0.094 12.8 1.5 14 5.8 0.4 3.1 2 1 0 2 2 2 0 Fn3-like domain from Purple Acid Phosphatase ChapFlgA PF13144.6 EGC38035.1 - 0.14 12.3 9.2 0.11 12.6 4.4 2.9 1 1 1 2 2 2 0 Chaperone for flagella basal body P-ring formation HC2 PF07382.11 EGC38035.1 - 6.6 6.8 6.9 11 6.0 6.9 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Myosin_head PF00063.21 EGC38036.1 - 2.1e-132 442.7 13.4 2.1e-132 442.7 13.4 3.5 3 0 0 3 3 3 1 Myosin head (motor domain) MyTH4 PF00784.17 EGC38036.1 - 6.1e-51 171.4 0.1 7.7e-28 97.1 0.0 5.0 4 0 0 4 4 4 2 MyTH4 domain FERM_M PF00373.18 EGC38036.1 - 5.5e-20 71.9 0.1 5e-13 49.5 0.0 6.0 4 1 0 4 4 4 2 FERM central domain IQ PF00612.27 EGC38036.1 - 5.1e-07 28.9 3.6 0.0018 17.9 0.2 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif SH3_9 PF14604.6 EGC38036.1 - 0.0076 16.1 0.0 0.022 14.6 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain FERM_N PF09379.10 EGC38036.1 - 0.01 15.8 0.3 0.83 9.6 0.1 2.9 2 0 0 2 2 2 0 FERM N-terminal domain Trypan_PARP PF05887.11 EGC38036.1 - 5.5 7.0 24.4 25 4.8 24.4 2.2 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) S1 PF00575.23 EGC38037.1 - 3e-17 62.7 11.7 3.1e-07 30.6 0.1 6.5 7 0 0 7 7 7 4 S1 RNA binding domain RNase_II_C_S1 PF18614.1 EGC38037.1 - 0.045 13.7 0.0 0.14 12.1 0.0 1.8 1 0 0 1 1 1 0 RNase II-type exonuclease C-terminal S1 domain CPP1-like PF11833.8 EGC38038.1 - 0.89 9.2 7.0 98 2.5 7.0 2.6 1 1 0 1 1 1 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Lig_chan PF00060.26 EGC38038.1 - 2.3 8.0 4.5 1.2 9.0 0.7 2.4 2 1 0 2 2 2 0 Ligand-gated ion channel AtpR PF12966.7 EGC38038.1 - 6.8 7.2 14.5 0.13 12.7 3.2 3.4 3 0 0 3 3 3 0 N-ATPase, AtpR subunit Pkinase PF00069.25 EGC38039.1 - 1.3e-72 244.4 0.0 1.7e-72 244.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38039.1 - 4.2e-31 108.2 0.0 5.3e-31 107.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC38039.1 - 0.0004 19.8 0.2 0.00059 19.2 0.2 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Haspin_kinase PF12330.8 EGC38039.1 - 0.00045 19.3 0.2 0.00045 19.3 0.2 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Kinase-like PF14531.6 EGC38039.1 - 0.0077 15.6 0.0 1.4 8.2 0.0 2.3 1 1 0 2 2 2 2 Kinase-like APH PF01636.23 EGC38039.1 - 0.038 13.9 0.1 0.2 11.5 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family RT_RNaseH_2 PF17919.1 EGC38039.1 - 0.074 13.1 0.1 0.48 10.5 0.0 2.3 2 0 0 2 2 2 0 RNase H-like domain found in reverse transcriptase Glyco_transf_8 PF01501.20 EGC38040.1 - 2.7e-10 40.3 1.0 2.7e-10 40.3 1.0 1.8 1 1 1 2 2 2 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.8 EGC38040.1 - 0.0019 17.6 1.4 0.0023 17.4 0.1 1.7 1 1 1 2 2 2 1 Mannosyltransferase putative Glyco_hydro_130 PF04041.13 EGC38040.1 - 0.0047 15.9 0.0 0.0088 15.0 0.0 1.4 1 0 0 1 1 1 1 beta-1,4-mannooligosaccharide phosphorylase DUF3139 PF11337.8 EGC38040.1 - 0.049 14.3 7.4 0.1 13.3 7.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SpoIIIAH PF12685.7 EGC38041.1 - 0.00027 20.9 3.7 0.00032 20.6 3.7 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein Ac76 PF05814.11 EGC38041.1 - 0.007 16.3 0.2 0.007 16.3 0.2 1.6 2 0 0 2 2 2 1 Orf76 (Ac76) DUF1189 PF06691.11 EGC38041.1 - 0.082 12.5 3.3 0.13 11.9 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1189) CLN3 PF02487.17 EGC38041.1 - 0.086 11.9 1.3 0.11 11.6 1.3 1.2 1 0 0 1 1 1 0 CLN3 protein FeoB_associated PF12669.7 EGC38041.1 - 0.089 13.2 0.2 0.14 12.6 0.2 1.2 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF4834 PF16118.5 EGC38041.1 - 0.16 12.9 11.6 10 7.1 11.6 2.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) O-antigen_lig PF13425.6 EGC38041.1 - 0.66 8.7 5.2 0.68 8.7 5.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein Ctr PF04145.15 EGC38041.1 - 3.6 8.2 6.6 8.3 7.0 6.6 1.6 1 1 0 1 1 1 0 Ctr copper transporter family HCO3_cotransp PF00955.21 EGC38041.1 - 5.5 5.7 5.1 6.7 5.4 5.1 1.2 1 0 0 1 1 1 0 HCO3- transporter family 7TM_GPCR_Srw PF10324.9 EGC38041.1 - 8.2 5.6 7.8 1.1 8.5 3.4 1.6 1 1 1 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw OTU PF02338.19 EGC38043.1 - 7.4e-15 55.6 0.1 7.4e-15 55.6 0.1 3.2 3 1 0 3 3 3 1 OTU-like cysteine protease PRAS PF15798.5 EGC38043.1 - 0.22 12.1 3.8 0.26 11.9 2.2 2.1 1 1 1 2 2 2 0 Proline-rich AKT1 substrate 1 Gar1 PF04410.14 EGC38044.1 - 3.3e-29 101.7 21.9 1.3e-21 76.9 9.2 6.4 2 2 4 6 6 6 2 Gar1/Naf1 RNA binding region BRO1 PF03097.18 EGC38045.1 - 3.2e-109 365.3 7.5 3.2e-109 365.3 7.5 2.5 2 1 1 3 3 3 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.6 EGC38045.1 - 1e-71 241.7 22.2 1e-71 241.7 22.2 2.9 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV KxDL PF10241.9 EGC38045.1 - 0.022 15.0 2.7 0.022 15.0 2.7 3.7 4 0 0 4 4 4 0 Uncharacterized conserved protein DUF4473 PF14747.6 EGC38045.1 - 4.5 7.9 9.7 3.4 8.3 0.5 4.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4473) Pkinase PF00069.25 EGC38046.1 - 2.3e-28 99.3 0.0 1.1e-18 67.5 0.0 2.6 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38046.1 - 0.00019 20.8 0.0 0.49 9.6 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Presenilin PF01080.17 EGC38046.1 - 0.0013 17.5 6.0 0.0015 17.4 6.0 1.1 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 EGC38046.1 - 0.051 11.9 8.8 0.058 11.7 8.8 1.1 1 0 0 1 1 1 0 CDC45-like protein SLC12 PF03522.15 EGC38046.1 - 0.37 9.8 9.7 0.5 9.3 9.7 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 EGC38046.1 - 0.75 8.3 14.4 0.96 7.9 14.4 1.1 1 0 0 1 1 1 0 Macoilin family SprA-related PF12118.8 EGC38046.1 - 1.1 8.4 14.1 1.5 7.9 14.1 1.1 1 0 0 1 1 1 0 SprA-related family Zip PF02535.22 EGC38046.1 - 3.7 6.7 6.8 4.6 6.4 6.8 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Hydrolase_3 PF08282.12 EGC38049.1 - 1.6e-64 218.1 0.0 1.8e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.13 EGC38049.1 - 2.4e-07 30.6 0.0 0.00095 18.8 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.26 EGC38049.1 - 5.2e-05 23.6 0.0 0.077 13.3 0.0 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase HAD_2 PF13419.6 EGC38049.1 - 0.00021 21.4 0.0 0.36 10.9 0.0 2.5 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC38049.1 - 0.0018 18.7 0.1 2.3 8.6 0.0 3.1 2 1 1 3 3 3 1 haloacid dehalogenase-like hydrolase DUF2054 PF10218.9 EGC38050.1 - 5.3e-30 104.2 32.7 5.6e-24 84.7 15.1 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2054) DUF4599 PF15371.6 EGC38050.1 - 0.012 16.2 0.3 0.029 14.9 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4599) Utp14 PF04615.13 EGC38050.1 - 0.75 8.3 19.6 0.88 8.1 19.6 1.1 1 0 0 1 1 1 0 Utp14 protein Raftlin PF15250.6 EGC38050.1 - 1 8.0 12.5 1.3 7.7 12.5 1.3 1 0 0 1 1 1 0 Raftlin Nop14 PF04147.12 EGC38050.1 - 1.3 7.2 15.2 1.5 7.0 15.2 1.1 1 0 0 1 1 1 0 Nop14-like family Ndc1_Nup PF09531.10 EGC38050.1 - 1.3 7.6 18.6 2 7.0 18.6 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ABC2_membrane_3 PF12698.7 EGC38050.1 - 6.3 5.8 18.9 9.3 5.3 18.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SOG2 PF10428.9 EGC38050.1 - 6.4 5.9 24.5 8.5 5.4 24.5 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein zf-RING_12 PF17976.1 EGC38051.1 - 0.077 13.3 0.9 0.12 12.6 0.9 1.3 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Methyltransf_3 PF01596.17 EGC38052.1 - 1.9e-63 213.5 0.3 2.3e-63 213.2 0.3 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGC38052.1 - 1.1e-12 48.9 0.0 1.8e-12 48.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38052.1 - 8.5e-05 23.2 0.0 0.00017 22.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38052.1 - 0.00016 21.5 0.1 0.00023 21.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.20 EGC38052.1 - 0.00041 19.7 0.1 0.0005 19.5 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_32 PF13679.6 EGC38052.1 - 0.02 14.9 0.0 0.1 12.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain GCD14 PF08704.10 EGC38052.1 - 0.022 14.5 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit PCMT PF01135.19 EGC38052.1 - 0.023 14.4 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGC38052.1 - 0.067 13.9 0.1 0.32 11.7 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain ESP PF16590.5 EGC38052.1 - 0.099 12.9 0.1 0.29 11.4 0.0 1.8 2 0 0 2 2 2 0 Exocrine gland-secreting peptide Methyltransf_18 PF12847.7 EGC38052.1 - 0.12 12.3 0.1 0.28 11.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_12 PF08242.12 EGC38052.1 - 0.12 13.1 0.1 0.75 10.6 0.0 2.1 1 1 1 2 2 2 0 Methyltransferase domain efThoc1 PF11957.8 EGC38053.1 - 8e-63 212.8 29.3 3.1e-61 207.5 14.0 3.4 2 1 1 3 3 3 2 THO complex subunit 1 transcription elongation factor SSP160 PF06933.11 EGC38053.1 - 2.5 6.2 12.4 5.2 5.2 12.4 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.8 EGC38053.1 - 2.9 7.9 8.1 4 7.4 5.6 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LSM PF01423.22 EGC38054.1 - 2.3e-17 62.4 1.0 2.6e-17 62.2 1.0 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC38054.1 - 0.00055 20.0 0.0 0.00067 19.7 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain Hfq PF17209.3 EGC38054.1 - 0.14 11.8 0.0 0.18 11.5 0.0 1.2 1 0 0 1 1 1 0 Hfq protein rRNA_proc-arch PF13234.6 EGC38055.1 - 8.8e-65 219.3 0.8 8.8e-65 219.3 0.8 2.1 2 1 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.12 EGC38055.1 - 3.2e-48 163.5 0.0 8.4e-48 162.1 0.0 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.29 EGC38055.1 - 6.6e-19 68.3 0.0 1.8e-18 66.9 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC38055.1 - 3.1e-06 27.5 0.4 6.5e-05 23.2 0.0 3.2 2 1 0 2 2 2 1 Helicase conserved C-terminal domain AAA_22 PF13401.6 EGC38055.1 - 0.032 14.5 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain Methyltransf_4 PF02390.17 EGC38056.1 - 1.1e-51 174.8 0.0 1.3e-51 174.5 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_25 PF13649.6 EGC38056.1 - 0.00033 21.3 0.0 0.00077 20.1 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38056.1 - 0.0023 17.7 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC38056.1 - 0.02 15.6 0.0 0.05 14.4 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGC38056.1 - 0.023 14.2 0.0 0.033 13.7 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_32 PF13679.6 EGC38056.1 - 0.026 14.5 0.0 0.042 13.8 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain FNIP PF05725.12 EGC38057.1 - 2.9e-39 133.0 70.2 9.3e-12 44.9 0.6 11.6 9 2 2 12 12 12 9 FNIP Repeat DUF1769 PF08588.10 EGC38057.1 - 0.0016 18.6 1.6 13 6.1 0.0 5.2 5 0 0 5 5 5 1 Protein of unknown function (DUF1769) Dicty_CAR PF05462.11 EGC38058.1 - 3.1e-06 26.6 11.8 6.1e-06 25.6 11.8 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Fz PF01392.22 EGC38058.1 - 0.0072 16.9 2.4 0.014 16.0 2.4 1.4 1 0 0 1 1 1 1 Fz domain Pkinase PF00069.25 EGC38059.1 - 1.5e-72 244.1 0.0 2.2e-72 243.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38059.1 - 2.2e-29 102.5 0.0 3.5e-29 101.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Med18 PF09637.10 EGC38060.1 - 4.9e-07 29.8 0.1 5.7e-07 29.6 0.1 1.3 1 0 0 1 1 1 1 Med18 protein DUF2067 PF09840.9 EGC38060.1 - 0.13 11.8 0.1 0.2 11.2 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2067) MFS_1 PF07690.16 EGC38061.1 - 3.8e-41 141.2 51.3 4.2e-32 111.4 29.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC38061.1 - 2.4e-08 33.3 32.9 6.2e-07 28.6 32.8 2.7 1 1 0 1 1 1 1 Sugar (and other) transporter Dehydrin PF00257.19 EGC38061.1 - 0.019 15.5 0.7 0.034 14.7 0.7 1.3 1 0 0 1 1 1 0 Dehydrin DUF4834 PF16118.5 EGC38061.1 - 0.46 11.5 15.4 15 6.6 0.5 4.2 3 1 0 3 3 3 0 Domain of unknown function (DUF4834) DUF4337 PF14235.6 EGC38061.1 - 4.8 7.3 7.4 0.16 12.1 0.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FYVE PF01363.21 EGC38062.1 - 1.6e-17 63.4 10.0 3.6e-17 62.2 10.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_N PF00339.29 EGC38062.1 - 3.5e-07 30.4 2.8 0.0011 19.1 0.2 3.1 3 0 0 3 3 3 2 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.22 EGC38062.1 - 0.00014 22.4 21.8 0.01 16.3 3.0 4.2 3 2 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Asp_Arg_Hydrox PF05118.15 EGC38062.1 - 0.0096 15.8 0.1 0.019 14.8 0.1 1.5 1 0 0 1 1 1 1 Aspartyl/Asparaginyl beta-hydroxylase FNIP PF05725.12 EGC38063.1 - 6.9e-43 144.6 57.2 1.8e-11 44.0 0.4 11.4 8 2 5 14 14 14 10 FNIP Repeat Nbl1_Borealin_N PF10444.9 EGC38063.1 - 0.029 14.0 0.1 0.47 10.1 0.0 3.0 4 0 0 4 4 4 0 Nbl1 / Borealin N terminal Mog1 PF04603.12 EGC38065.1 - 1.6e-38 132.2 0.7 2.5e-38 131.6 0.7 1.3 1 0 0 1 1 1 1 Ran-interacting Mog1 protein SRP14 PF02290.15 EGC38065.1 - 0.036 14.4 0.3 0.068 13.5 0.2 1.6 1 1 0 1 1 1 0 Signal recognition particle 14kD protein Lung_7-TM_R PF06814.13 EGC38066.1 - 2.4e-27 96.0 9.1 3e-27 95.6 9.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Lung_7-TM_R PF06814.13 EGC38067.1 - 9.1e-11 41.5 7.8 1.1e-10 41.3 7.8 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor ASC PF00858.24 EGC38067.1 - 0.0079 15.2 2.0 0.01 14.8 2.0 1.1 1 0 0 1 1 1 1 Amiloride-sensitive sodium channel BCAS3 PF12490.8 EGC38067.1 - 0.072 12.6 3.6 0.093 12.2 3.6 1.1 1 0 0 1 1 1 0 Breast carcinoma amplified sequence 3 DNA_primase_S PF01896.19 EGC38068.1 - 9.8e-49 165.8 0.8 1.6e-48 165.1 0.8 1.3 1 0 0 1 1 1 1 DNA primase small subunit SbcD_C PF12320.8 EGC38068.1 - 0.0069 16.7 0.1 1.9 8.9 0.0 2.4 2 0 0 2 2 2 2 Type 5 capsule protein repressor C-terminal domain Imm74 PF15603.6 EGC38068.1 - 0.051 13.8 0.0 0.57 10.4 0.0 2.6 2 0 0 2 2 2 0 Immunity protein 74 Erp_C PF06780.11 EGC38068.1 - 1.7 8.7 5.4 0.2 11.7 0.3 2.1 3 0 0 3 3 3 0 Erp protein C-terminus BP28CT PF08146.12 EGC38069.1 - 6.1e-35 120.4 7.8 6.1e-35 120.4 7.8 4.6 3 1 0 3 3 3 1 BP28CT (NUC211) domain HEAT PF02985.22 EGC38069.1 - 9e-05 22.4 0.1 7.7 7.1 0.0 5.6 4 0 0 4 4 4 1 HEAT repeat U3snoRNP10 PF12397.8 EGC38069.1 - 0.00017 21.9 1.6 0.00017 21.9 1.6 8.5 8 2 1 9 9 9 1 U3 small nucleolar RNA-associated protein 10 UME PF08064.13 EGC38069.1 - 0.005 16.7 13.3 0.18 11.7 0.3 5.3 6 0 0 6 6 6 2 UME (NUC010) domain FAM176 PF14851.6 EGC38069.1 - 5.9 6.5 7.8 5.9 6.5 1.6 2.7 2 0 0 2 2 2 0 FAM176 family PBP1_TM PF14812.6 EGC38069.1 - 6.6 7.2 10.8 0.36 11.2 1.9 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.6 EGC38069.1 - 8.2 6.7 13.0 1.7 9.0 1.6 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4611) DUF2052 PF09747.9 EGC38069.1 - 9.6 6.3 11.7 0.91 9.6 0.8 3.2 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) DDE_Tnp_4 PF13359.6 EGC38070.1 - 3.6e-14 52.7 0.0 4.2e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC38070.1 - 1.1e-05 25.2 0.0 3.1e-05 23.7 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain TMEM71 PF15121.6 EGC38070.1 - 0.1 12.2 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 TMEM71 protein family CBM49 PF09478.10 EGC38071.1 - 5e-16 58.8 0.2 7.2e-16 58.3 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.19 EGC38071.1 - 0.00036 20.8 0.6 0.00056 20.2 0.6 1.3 1 0 0 1 1 1 1 Cellulose binding domain AP3B1_C PF14796.6 EGC38071.1 - 0.023 15.0 0.2 0.039 14.2 0.2 1.3 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal Fungus-induced PF10917.8 EGC38071.1 - 0.076 13.3 0.1 0.15 12.4 0.1 1.5 1 0 0 1 1 1 0 Fungus-induced protein DUF2393 PF09624.10 EGC38071.1 - 0.13 12.3 0.3 0.17 11.9 0.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2393) FNIP PF05725.12 EGC38072.1 - 1.7e-69 229.7 48.8 3.8e-13 49.4 0.1 7.8 3 2 7 10 10 10 10 FNIP Repeat zf-C3HC4_4 PF15227.6 EGC38072.1 - 7.4e-07 29.2 8.2 7.4e-07 29.2 8.2 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.24 EGC38072.1 - 1.2e-06 28.5 11.0 1.2e-06 28.5 11.0 3.3 3 1 0 3 3 3 1 B-box zinc finger Prok-RING_4 PF14447.6 EGC38072.1 - 0.003 17.4 6.7 0.003 17.4 6.7 2.5 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC38072.1 - 0.017 15.2 2.3 0.017 15.2 2.3 2.8 1 1 1 2 2 2 0 RING-type zinc-finger Dscam_C PF12355.8 EGC38072.1 - 0.074 14.0 0.1 0.074 14.0 0.1 2.3 1 1 1 2 2 2 0 Down syndrome cell adhesion molecule C terminal Gemini_AL2 PF01440.16 EGC38072.1 - 0.14 12.6 3.8 0.47 10.9 3.8 1.9 1 0 0 1 1 1 0 Geminivirus AL2 protein B12D PF06522.11 EGC38073.1 - 8.3e-06 25.5 0.0 9.1e-06 25.4 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit RhoGAP PF00620.27 EGC38074.1 - 1.4e-39 135.4 0.1 5.6e-39 133.4 0.1 2.1 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGC38074.1 - 4.3e-29 101.1 4.2 7.8e-21 74.6 1.0 2.5 2 0 0 2 2 2 2 PH domain RhoGEF PF00621.20 EGC38074.1 - 5.9e-29 101.6 0.4 5.9e-29 101.6 0.4 4.2 4 1 0 4 4 4 1 RhoGEF domain BAR_3 PF16746.5 EGC38074.1 - 2.6e-09 37.1 6.3 2.6e-09 37.1 6.3 2.6 1 1 1 2 2 2 1 BAR domain of APPL family PH_11 PF15413.6 EGC38074.1 - 4.6e-06 27.0 9.8 4.5e-05 23.8 0.9 3.3 3 0 0 3 3 3 2 Pleckstrin homology domain PH_16 PF17838.1 EGC38074.1 - 0.0058 16.5 0.3 18 5.2 0.0 3.7 3 0 0 3 3 3 1 PH domain COG5 PF10392.9 EGC38074.1 - 3.9 7.6 8.4 1.4 9.1 3.9 2.5 2 0 0 2 2 2 0 Golgi transport complex subunit 5 ALMT PF11744.8 EGC38074.1 - 5.8 5.6 13.7 3.9 6.2 11.6 1.7 1 1 0 1 1 1 0 Aluminium activated malate transporter Beta_helix PF13229.6 EGC38075.1 - 0.0032 17.3 21.3 0.0032 17.3 21.3 9.7 3 2 5 8 8 8 3 Right handed beta helix region TMEM51 PF15345.6 EGC38076.1 - 0.003 17.4 11.6 0.004 17.0 11.6 1.2 1 0 0 1 1 1 1 Transmembrane protein 51 Med15 PF09606.10 EGC38076.1 - 0.0057 15.4 21.4 0.0072 15.1 21.4 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Ly49 PF08391.10 EGC38076.1 - 0.0066 16.8 1.8 0.0066 16.8 1.8 1.7 2 0 0 2 2 2 1 Ly49-like protein, N-terminal region Spt20 PF12090.8 EGC38076.1 - 0.0077 15.9 24.0 0.0077 15.9 24.0 1.6 2 0 0 2 2 2 1 Spt20 family TAF4 PF05236.14 EGC38076.1 - 0.0079 16.0 5.0 0.0094 15.7 5.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family XRCC4 PF06632.12 EGC38076.1 - 0.0099 14.8 5.7 0.017 14.0 5.7 1.3 1 0 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 MscS_TM PF12794.7 EGC38076.1 - 0.01 14.7 0.2 0.013 14.4 0.2 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 FPN1 PF06963.12 EGC38076.1 - 0.011 14.4 1.9 0.013 14.1 1.9 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) WBP-1 PF11669.8 EGC38076.1 - 0.012 16.3 0.6 0.023 15.3 0.6 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 DUF4199 PF13858.6 EGC38076.1 - 0.014 15.8 0.6 0.02 15.3 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2681 PF10883.8 EGC38076.1 - 0.017 15.5 11.9 0.032 14.6 11.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) SID-1_RNA_chan PF13965.6 EGC38076.1 - 0.044 12.2 3.0 0.067 11.6 3.0 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3337 PF11816.8 EGC38076.1 - 0.046 13.6 2.6 0.095 12.6 2.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3337) DUF702 PF05142.12 EGC38076.1 - 0.068 13.6 7.0 0.11 13.0 7.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF702) FHIPEP PF00771.20 EGC38076.1 - 0.095 11.2 1.0 0.12 10.8 1.0 1.1 1 0 0 1 1 1 0 FHIPEP family DUF3169 PF11368.8 EGC38076.1 - 0.11 12.0 0.6 0.16 11.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Connexin PF00029.19 EGC38076.1 - 0.12 12.1 2.5 0.2 11.4 2.5 1.3 1 0 0 1 1 1 0 Connexin SPX PF03105.19 EGC38076.1 - 0.13 12.2 28.8 0.15 12.0 28.8 1.1 1 0 0 1 1 1 0 SPX domain CytochromB561_N PF09786.9 EGC38076.1 - 0.13 11.2 23.3 0.15 11.0 23.3 1.0 1 0 0 1 1 1 0 Cytochrome B561, N terminal Presenilin PF01080.17 EGC38076.1 - 0.14 10.9 8.7 0.14 10.9 8.7 1.2 1 0 0 1 1 1 0 Presenilin DUF4446 PF14584.6 EGC38076.1 - 0.14 12.1 3.1 0.25 11.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) PEX11 PF05648.14 EGC38076.1 - 0.15 11.5 3.7 0.23 10.9 3.7 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) CLN3 PF02487.17 EGC38076.1 - 0.17 10.9 3.2 0.27 10.2 3.2 1.3 1 0 0 1 1 1 0 CLN3 protein CSG2 PF16965.5 EGC38076.1 - 0.21 10.5 2.8 0.33 9.9 2.8 1.3 1 0 0 1 1 1 0 Ceramide synthase regulator Menin PF05053.13 EGC38076.1 - 0.22 9.8 8.8 0.29 9.5 8.8 1.1 1 0 0 1 1 1 0 Menin Tae4 PF14113.6 EGC38076.1 - 0.24 11.6 3.5 0.17 12.1 1.8 1.5 2 0 0 2 2 1 0 Type VI secretion system (T6SS), amidase effector protein 4 NEMP PF10225.9 EGC38076.1 - 0.27 10.9 4.9 0.37 10.4 4.9 1.2 1 0 0 1 1 1 0 NEMP family TssO PF17561.2 EGC38076.1 - 0.29 11.2 12.0 0.084 13.0 8.7 1.7 2 0 0 2 2 2 0 Type VI secretion system, TssO MPM1 PF17234.2 EGC38076.1 - 0.3 11.3 10.6 0.065 13.5 7.2 1.6 2 0 0 2 2 2 0 Mitochondrial peculiar membrane protein 1 DUF973 PF06157.11 EGC38076.1 - 0.31 10.1 2.2 0.42 9.6 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF973) Sporozoite_P67 PF05642.11 EGC38076.1 - 0.32 9.0 14.5 0.42 8.6 14.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.6 EGC38076.1 - 0.34 10.6 4.4 0.07 12.8 0.9 1.6 2 0 0 2 2 2 0 FAM176 family DivIC PF04977.15 EGC38076.1 - 0.4 10.5 12.3 0.65 9.8 12.3 1.4 1 0 0 1 1 1 0 Septum formation initiator Miga PF10265.9 EGC38076.1 - 0.4 9.6 12.7 0.5 9.3 12.7 1.2 1 0 0 1 1 1 0 Mitoguardin Folate_carrier PF01770.18 EGC38076.1 - 0.44 9.2 3.2 0.6 8.8 3.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF4834 PF16118.5 EGC38076.1 - 0.58 11.2 14.9 0.12 13.4 10.9 2.0 2 1 0 2 2 1 0 Domain of unknown function (DUF4834) Mcm10 PF09332.11 EGC38076.1 - 0.84 9.0 15.2 1.1 8.7 15.2 1.2 1 0 0 1 1 1 0 Mcm10 replication factor TERB2 PF15101.6 EGC38076.1 - 0.94 9.5 13.8 1.7 8.6 13.8 1.4 1 0 0 1 1 1 0 Telomere-associated protein TERB2 YABBY PF04690.13 EGC38076.1 - 1.8 9.1 9.8 0.44 11.1 6.6 1.6 2 0 0 2 2 1 0 YABBY protein GREB1 PF15782.5 EGC38076.1 - 1.9 5.5 22.1 2.4 5.2 22.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Tim54 PF11711.8 EGC38076.1 - 1.9 7.2 8.2 2.6 6.8 8.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 EIIBC-GUT_N PF03612.14 EGC38076.1 - 2.1 8.0 5.6 4 7.1 5.6 1.4 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF2232 PF09991.9 EGC38076.1 - 2.2 7.4 4.0 3 7.0 4.0 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) O-antigen_lig PF13425.6 EGC38076.1 - 3.4 6.4 7.2 0.22 10.3 1.8 1.6 2 0 0 2 2 2 0 O-antigen ligase like membrane protein FAM76 PF16046.5 EGC38076.1 - 4.2 6.6 14.8 4.7 6.5 14.0 1.5 1 1 0 1 1 1 0 FAM76 protein NicO PF03824.16 EGC38076.1 - 4.2 6.6 5.9 1.5 8.1 0.1 2.0 2 0 0 2 2 2 0 High-affinity nickel-transport protein ALMT PF11744.8 EGC38076.1 - 4.8 5.9 9.2 7.4 5.3 9.2 1.3 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec62 PF03839.16 EGC38076.1 - 6.1 6.3 8.1 0.79 9.2 4.1 1.5 2 0 0 2 2 2 0 Translocation protein Sec62 Inhibitor_I36 PF03995.13 EGC38077.1 - 0.0095 15.8 0.0 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Peptidase inhibitor family I36 EGF_2 PF07974.13 EGC38078.1 - 0.027 14.8 13.1 0.052 13.9 13.1 1.5 1 0 0 1 1 1 0 EGF-like domain DUF3671 PF12420.8 EGC38078.1 - 0.027 14.5 1.9 0.035 14.2 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function TMEM154 PF15102.6 EGC38078.1 - 0.028 14.3 0.2 0.028 14.3 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family hEGF PF12661.7 EGC38078.1 - 1.1 10.0 7.0 3.1 8.6 7.0 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF EGF_Tenascin PF18720.1 EGC38078.1 - 8.3 6.6 9.2 15 5.8 9.2 1.5 1 0 0 1 1 1 0 Tenascin EGF domain FNIP PF05725.12 EGC38079.1 - 3.7e-25 87.8 41.0 8.2e-07 29.1 0.0 7.3 7 1 1 8 8 8 5 FNIP Repeat bZIP_1 PF00170.21 EGC38079.1 - 0.13 12.3 2.5 0.28 11.3 2.5 1.5 1 0 0 1 1 1 0 bZIP transcription factor TMEMspv1-c74-12 PF11044.8 EGC38080.1 - 0.0047 16.9 1.9 1.9 8.6 0.1 2.4 2 0 0 2 2 2 2 Plectrovirus spv1-c74 ORF 12 transmembrane protein SKG6 PF08693.10 EGC38080.1 - 0.0076 15.6 0.7 0.014 14.8 0.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.13 EGC38080.1 - 0.065 13.6 10.9 0.15 12.5 10.9 1.7 1 0 0 1 1 1 0 EGF-like domain ETRAMP PF09716.10 EGC38080.1 - 0.083 13.0 2.7 0.12 12.5 1.0 2.3 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Laminin_EGF PF00053.24 EGC38080.1 - 9.9 6.4 12.9 0.52 10.5 6.8 2.1 2 0 0 2 2 2 0 Laminin EGF domain GCP_C_terminal PF04130.13 EGC38081.1 - 9.6e-72 242.0 14.7 9.6e-72 242.0 14.7 3.3 4 1 0 4 4 4 1 Gamma tubulin complex component C-terminal GCP_N_terminal PF17681.1 EGC38081.1 - 6.5e-70 236.2 8.9 6.5e-70 236.2 8.9 2.2 2 0 0 2 2 2 1 Gamma tubulin complex component N-terminal Phage_int_SAM_1 PF02899.17 EGC38081.1 - 0.5 10.7 2.9 0.81 10.0 0.4 2.8 3 0 0 3 3 3 0 Phage integrase, N-terminal SAM-like domain Oxidored_q6 PF01058.22 EGC38082.1 - 8.7e-22 77.3 0.2 1.1e-21 77.0 0.2 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit Tmemb_14 PF03647.13 EGC38082.1 - 0.083 13.6 0.0 0.14 12.9 0.0 1.4 1 0 0 1 1 1 0 Transmembrane proteins 14C FA_desaturase PF00487.24 EGC38083.1 - 1.5e-36 126.6 16.6 1.5e-36 126.6 16.6 1.6 1 1 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGC38083.1 - 5.1e-23 81.0 0.0 1.4e-22 79.6 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.6 EGC38083.1 - 0.045 13.9 0.2 0.11 12.7 0.2 1.6 1 0 0 1 1 1 0 Cleavage inducing molecular chaperone CitMHS PF03600.16 EGC38084.1 - 9.8e-44 149.7 0.0 7.2e-43 146.9 0.0 1.9 1 1 1 2 2 2 1 Citrate transporter ArsB PF02040.15 EGC38084.1 - 2.4e-09 37.0 13.4 2.4e-09 37.0 13.4 2.1 2 0 0 2 2 2 1 Arsenical pump membrane protein DUF5308 PF17233.2 EGC38084.1 - 0.041 14.1 0.1 0.11 12.7 0.1 1.5 1 1 0 1 1 1 0 Family of unknown function (DUF5308) N6-adenineMlase PF10237.9 EGC38084.1 - 0.073 12.9 0.3 0.073 12.9 0.3 1.8 1 1 1 2 2 2 0 Probable N6-adenine methyltransferase LolA PF03548.15 EGC38085.1 - 0.066 12.9 2.0 0.13 12.0 1.4 1.7 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Ras PF00071.22 EGC38087.1 - 3.6e-08 33.2 2.0 2.8e-07 30.3 2.0 2.1 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC38087.1 - 0.00047 20.4 0.8 0.0056 16.9 0.2 2.4 1 1 1 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Septin PF00735.18 EGC38087.1 - 0.00099 18.5 0.3 0.00099 18.5 0.3 2.1 2 1 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGC38087.1 - 0.0015 18.6 1.0 0.0015 18.6 1.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase CENP-M PF11111.8 EGC38087.1 - 0.0021 17.3 0.6 0.036 13.2 0.3 2.3 1 1 0 2 2 2 1 Centromere protein M (CENP-M) Sulfotransfer_3 PF13469.6 EGC38087.1 - 0.0039 17.6 0.0 0.014 15.8 0.0 1.8 2 0 0 2 2 2 1 Sulfotransferase family AAA_22 PF13401.6 EGC38087.1 - 0.011 16.0 0.5 0.062 13.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain PduV-EutP PF10662.9 EGC38087.1 - 0.014 15.1 0.1 0.039 13.7 0.0 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.6 EGC38087.1 - 0.02 15.4 0.3 0.1 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.6 EGC38087.1 - 0.024 14.9 0.0 0.048 13.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGC38087.1 - 0.031 14.0 0.0 0.06 13.1 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGC38087.1 - 0.08 13.0 2.1 0.1 12.6 0.4 2.2 1 1 1 2 2 2 0 AAA domain RsgA_GTPase PF03193.16 EGC38087.1 - 0.15 12.0 3.4 1.1 9.2 0.7 2.6 1 1 1 2 2 2 0 RsgA GTPase ABC_tran PF00005.27 EGC38087.1 - 3.7 8.1 7.8 6.5 7.3 7.8 1.7 1 1 0 1 1 1 0 ABC transporter SIS PF01380.22 EGC38088.1 - 3.8e-43 146.5 1.4 1.6e-21 76.5 0.1 2.4 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.6 EGC38088.1 - 8e-21 74.6 0.0 1.7e-20 73.6 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.6 EGC38088.1 - 9.6e-17 61.0 0.0 2e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF2529 PF10740.9 EGC38088.1 - 0.064 12.9 0.6 2.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF2529) GATase_4 PF13230.6 EGC38088.1 - 0.064 12.1 0.3 0.16 10.9 0.3 1.6 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Glyco_transf_29 PF00777.18 EGC38088.1 - 0.16 11.4 0.0 0.31 10.4 0.0 1.4 1 0 0 1 1 1 0 Glycosyltransferase family 29 (sialyltransferase) Transthyretin PF00576.21 EGC38089.1 - 4.4e-34 117.5 0.1 5.4e-34 117.2 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.6 EGC38089.1 - 0.00013 22.2 0.0 0.00018 21.7 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain SdrD_B PF17210.3 EGC38089.1 - 0.011 15.9 0.2 0.016 15.4 0.2 1.4 1 0 0 1 1 1 0 SdrD B-like domain Lactamase_B_4 PF13691.6 EGC38091.1 - 0.2 11.3 0.0 0.29 10.8 0.0 1.3 1 0 0 1 1 1 0 tRNase Z endonuclease Branch PF02485.21 EGC38092.1 - 3.3e-09 36.6 5.2 1.4e-08 34.5 5.2 2.1 1 1 0 1 1 1 1 Core-2/I-Branching enzyme TLD PF07534.16 EGC38093.1 - 9.7e-17 61.5 3.8 9.7e-17 61.5 3.8 1.8 2 0 0 2 2 2 1 TLD BTB_2 PF02214.22 EGC38093.1 - 1.1e-13 51.3 0.0 3.2e-13 49.8 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_3 PF13920.6 EGC38094.1 - 3.7e-10 39.5 14.8 4.9e-10 39.1 14.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38094.1 - 5.3e-10 39.0 16.2 5.3e-10 39.0 16.2 1.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC38094.1 - 1.1e-07 31.6 13.6 3.2e-07 30.1 13.6 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC38094.1 - 2.6e-07 30.4 13.4 4.4e-07 29.7 13.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38094.1 - 4e-07 30.2 17.4 4e-07 30.2 17.4 1.4 2 0 0 2 2 2 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC38094.1 - 3e-06 27.1 14.0 4.8e-06 26.5 6.6 2.1 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38094.1 - 4.8e-06 26.4 11.4 9.9e-06 25.4 11.4 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC38094.1 - 0.00013 22.1 14.0 0.00035 20.6 14.2 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.7 EGC38094.1 - 0.0017 18.6 12.4 0.0034 17.7 12.4 1.5 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGC38094.1 - 0.032 14.0 9.3 0.032 14.0 9.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC38094.1 - 0.22 11.7 13.6 0.29 11.3 13.6 1.2 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC38094.1 - 0.57 10.3 9.3 0.78 9.8 9.3 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger FNIP PF05725.12 EGC38095.1 - 2.5e-23 82.0 14.3 1.3e-11 44.4 0.1 5.6 2 2 2 5 5 5 4 FNIP Repeat LRR_5 PF13306.6 EGC38095.1 - 0.0017 18.3 0.3 0.0047 16.9 0.0 1.9 2 0 0 2 2 2 1 BspA type Leucine rich repeat region (6 copies) ETRAMP PF09716.10 EGC38097.1 - 6.5 6.9 16.6 15 5.8 1.9 4.8 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.12 EGC38099.1 - 1e-125 409.7 77.7 1.2e-14 54.1 1.0 11.4 5 3 8 14 14 14 14 FNIP Repeat LRR_5 PF13306.6 EGC38099.1 - 6.6e-07 29.3 4.2 1.1 9.2 0.0 4.3 3 1 1 4 4 4 3 BspA type Leucine rich repeat region (6 copies) MbeB_N PF04837.12 EGC38099.1 - 0.041 14.2 0.3 46 4.4 0.0 4.0 4 0 0 4 4 4 0 MbeB-like, N-term conserved region FNIP PF05725.12 EGC38100.1 - 2.2e-69 229.4 18.6 4.7e-15 55.5 0.1 7.8 5 2 3 8 8 8 8 FNIP Repeat Nbl1_Borealin_N PF10444.9 EGC38100.1 - 0.1 12.2 0.0 18 5.1 0.0 4.1 5 0 0 5 5 5 0 Nbl1 / Borealin N terminal Secretin_N_2 PF07655.13 EGC38100.1 - 2.2 8.9 9.1 4.4 7.9 9.1 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Endotoxin_N PF03945.14 EGC38101.1 - 1.7e-06 28.0 0.5 1.7e-06 28.0 0.5 1.8 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain DUF1938 PF09153.10 EGC38101.1 - 0.021 14.9 0.1 0.19 11.8 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1938) Cullin_Nedd8 PF10557.9 EGC38101.1 - 0.1 12.6 0.0 0.28 11.2 0.0 1.7 1 0 0 1 1 1 0 Cullin protein neddylation domain ABC_membrane PF00664.23 EGC38102.1 - 8.5e-129 429.0 18.5 5.7e-65 219.7 2.6 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC38102.1 - 5.9e-71 237.4 0.1 2.5e-34 118.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGC38102.1 - 5e-14 52.3 0.0 2.6e-06 27.0 0.0 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGC38102.1 - 3.2e-08 32.8 0.4 0.0016 17.3 0.1 2.4 2 0 0 2 2 2 2 Predicted ATPase of the ABC class RsgA_GTPase PF03193.16 EGC38102.1 - 1.9e-05 24.6 0.0 0.092 12.6 0.0 2.5 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGC38102.1 - 2.2e-05 24.7 0.5 0.23 11.7 0.0 3.3 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.6 EGC38102.1 - 5.2e-05 22.9 1.4 0.22 11.3 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.6 EGC38102.1 - 0.0009 19.4 3.8 2 8.7 0.2 4.0 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_7 PF12775.7 EGC38102.1 - 0.0012 18.4 0.0 1.8 8.1 0.0 2.6 2 0 0 2 2 2 2 P-loop containing dynein motor region AAA_16 PF13191.6 EGC38102.1 - 0.0051 17.2 1.2 3 8.2 0.0 2.9 2 2 0 2 2 2 2 AAA ATPase domain Zeta_toxin PF06414.12 EGC38102.1 - 0.0086 15.4 0.4 1 8.6 0.0 3.3 4 0 0 4 4 4 1 Zeta toxin AAA_18 PF13238.6 EGC38102.1 - 0.015 15.8 1.3 5.7 7.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_24 PF13479.6 EGC38102.1 - 0.021 14.5 0.1 1.3 8.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.6 EGC38102.1 - 0.047 13.5 1.1 13 5.5 0.1 3.8 4 0 0 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system Roc PF08477.13 EGC38102.1 - 0.096 12.9 0.0 9.8 6.4 0.0 2.8 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Phage_T4_Ndd PF06591.11 EGC38102.1 - 0.11 12.3 0.0 13 5.5 0.0 2.4 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) AAA_25 PF13481.6 EGC38102.1 - 0.16 11.5 0.2 5.9 6.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_5 PF07728.14 EGC38102.1 - 0.2 11.6 1.4 23 5.0 0.0 3.8 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGC38102.1 - 0.2 11.3 6.4 3.1 7.5 0.1 3.6 3 2 0 3 3 3 0 AAA domain RuvX PF03652.15 EGC38102.1 - 0.85 10.0 6.4 0.14 12.5 0.2 2.7 3 1 1 4 4 2 0 Holliday junction resolvase IstB_IS21 PF01695.17 EGC38102.1 - 0.99 9.1 4.2 56 3.4 0.1 3.6 4 0 0 4 4 4 0 IstB-like ATP binding protein TFIIA_gamma_C PF02751.14 EGC38103.1 - 2.3e-22 78.9 2.8 3.4e-22 78.3 2.8 1.3 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.16 EGC38103.1 - 3.2e-21 75.1 0.8 4.2e-21 74.7 0.8 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain Dopey_N PF04118.14 EGC38103.1 - 0.033 13.3 0.0 0.036 13.2 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal DUF4427 PF14468.6 EGC38103.1 - 0.065 13.3 0.1 0.092 12.8 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) His_Phos_1 PF00300.22 EGC38105.1 - 1.4e-38 132.5 0.0 5.1e-31 107.9 0.1 2.0 1 1 1 2 2 2 2 Histidine phosphatase superfamily (branch 1) FAD_binding_3 PF01494.19 EGC38106.1 - 5.3e-14 52.2 0.0 1.2e-12 47.8 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.10 EGC38106.1 - 0.0028 16.8 0.0 0.022 13.8 0.0 2.3 3 0 0 3 3 3 1 Squalene epoxidase Ras PF00071.22 EGC38107.1 - 1.9e-41 141.4 0.0 2.5e-41 141.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38107.1 - 6.9e-21 74.7 0.0 1.8e-20 73.4 0.0 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38107.1 - 8.2e-08 31.9 0.0 1.3e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC38107.1 - 0.038 13.7 0.0 1.7 8.3 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.6 EGC38107.1 - 0.09 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC38107.1 - 0.1 12.5 0.0 0.3 11.0 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_22 PF13401.6 EGC38107.1 - 0.12 12.7 0.0 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.6 EGC38108.1 - 0.0001 22.2 21.4 0.0037 17.1 21.4 3.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC38108.1 - 0.00017 21.4 0.0 0.00031 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGC38108.1 - 0.025 14.9 0.0 0.067 13.5 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGC38108.1 - 0.03 14.3 0.0 0.083 12.9 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC38108.1 - 0.033 14.6 0.1 0.13 12.7 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGC38108.1 - 0.042 14.3 0.1 0.4 11.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC38108.1 - 0.11 12.8 0.0 0.35 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain Spectrin PF00435.21 EGC38108.1 - 0.67 10.5 7.2 2 8.9 7.2 1.8 1 0 0 1 1 1 0 Spectrin repeat WHEP-TRS PF00458.20 EGC38108.1 - 0.93 9.7 7.0 0.74 10.0 3.7 2.5 1 1 1 2 2 2 0 WHEP-TRS domain Presenilin PF01080.17 EGC38109.1 - 1.3 7.7 20.0 1.7 7.3 20.0 1.2 1 0 0 1 1 1 0 Presenilin Dapper PF15268.6 EGC38109.1 - 6.9 5.4 16.2 8.7 5.1 16.2 1.1 1 0 0 1 1 1 0 Dapper Tim54 PF11711.8 EGC38109.1 - 6.9 5.3 10.8 12 4.5 10.8 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF3807 PF12720.7 EGC38109.1 - 8.3 6.6 17.7 15 5.8 17.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Methyltransf_32 PF13679.6 EGC38109.1 - 9.3 6.2 10.0 17 5.4 10.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain DUF4377 PF14302.6 EGC38110.1 - 0.047 13.8 0.3 0.15 12.1 0.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4377) DUF2013 PF09431.10 EGC38111.1 - 0.028 14.6 4.6 0.034 14.3 0.2 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF2013) NUDIX PF00293.28 EGC38112.1 - 1.5e-13 50.9 0.0 1.9e-13 50.6 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain Erf4 PF10256.9 EGC38113.1 - 0.0002 21.5 0.5 0.00057 20.0 0.3 1.9 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Cyt_bd_oxida_I PF01654.17 EGC38113.1 - 0.016 13.9 0.3 0.022 13.4 0.3 1.1 1 0 0 1 1 1 0 Cytochrome bd terminal oxidase subunit I Homeobox_KN PF05920.11 EGC38115.1 - 8.5e-09 35.2 2.2 1.2e-08 34.7 0.2 2.3 2 0 0 2 2 2 1 Homeobox KN domain Homeodomain PF00046.29 EGC38115.1 - 3.5e-07 30.0 2.8 9.8e-07 28.5 2.8 1.8 1 0 0 1 1 1 1 Homeodomain Fe_bilin_red PF05996.12 EGC38116.1 - 0.021 14.5 1.7 0.027 14.2 1.7 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase LMBR1 PF04791.16 EGC38116.1 - 0.15 10.9 4.3 0.16 10.8 4.3 1.0 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 EGC38116.1 - 0.2 10.4 6.3 0.26 10.0 6.3 1.3 1 0 0 1 1 1 0 Presenilin PA26 PF04636.13 EGC38116.1 - 0.43 9.4 6.6 0.5 9.2 6.6 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GET2 PF08690.10 EGC38116.1 - 3.4 7.2 12.5 4.4 6.9 12.5 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 MAP70 PF07058.11 EGC38116.1 - 6.4 5.4 13.3 7.3 5.2 13.3 1.0 1 0 0 1 1 1 0 Microtubule-associated protein 70 AMP-binding PF00501.28 EGC38117.1 - 8.1e-70 235.5 0.0 9.8e-70 235.3 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC38117.1 - 1.3e-14 53.9 2.7 2.4e-14 53.0 2.7 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC38117.1 - 9.6e-07 29.7 0.0 2.2e-06 28.5 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pec_lyase_C PF00544.19 EGC38117.1 - 0.063 12.9 0.1 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Pectate lyase Brix PF04427.18 EGC38118.1 - 1.8e-22 80.4 0.2 3.1e-22 79.6 0.2 1.3 1 0 0 1 1 1 1 Brix domain DUF1294 PF06961.13 EGC38119.1 - 6.7e-19 67.9 0.8 6.7e-19 67.9 0.8 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) ARL2_Bind_BART PF11527.8 EGC38119.1 - 0.0049 17.0 1.9 0.0081 16.3 1.9 1.3 1 0 0 1 1 1 1 The ARF-like 2 binding protein BART ANAPC15 PF15243.6 EGC38119.1 - 0.014 15.8 1.1 0.02 15.3 1.1 1.3 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 15 NADH-u_ox-rdase PF10785.9 EGC38119.1 - 0.05 14.3 0.3 0.12 13.0 0.2 1.6 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit NEMP PF10225.9 EGC38119.1 - 0.086 12.5 0.1 0.13 12.0 0.1 1.2 1 0 0 1 1 1 0 NEMP family SRP68 PF16969.5 EGC38121.1 - 3.7e-102 343.1 23.6 4.6e-102 342.8 23.6 1.1 1 0 0 1 1 1 1 RNA-binding signal recognition particle 68 Enkurin PF13864.6 EGC38121.1 - 9.2 6.8 9.4 1.8 9.0 2.9 2.8 2 0 0 2 2 2 0 Calmodulin-binding Peptidase_M28 PF04389.17 EGC38122.1 - 2.9e-21 76.1 0.1 4.1e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.28 EGC38122.1 - 1.6e-08 34.5 0.4 6.9e-08 32.4 0.1 1.9 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 PA PF02225.22 EGC38122.1 - 0.00086 19.3 0.1 0.0017 18.3 0.1 1.5 1 0 0 1 1 1 1 PA domain DUF3671 PF12420.8 EGC38122.1 - 0.0029 17.7 1.3 0.0056 16.7 1.3 1.4 1 0 0 1 1 1 1 Protein of unknown function YukC PF10140.9 EGC38122.1 - 0.15 10.9 0.3 0.22 10.3 0.3 1.2 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukC ETRAMP PF09716.10 EGC38122.1 - 0.21 11.6 0.7 0.66 10.1 0.1 2.0 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Membrane_bind PF14564.6 EGC38123.1 - 3.2e-40 137.0 0.1 4.9e-40 136.4 0.1 1.2 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.10 EGC38123.1 - 2e-36 124.0 0.1 3e-36 123.4 0.1 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin Syncollin PF15138.6 EGC38123.1 - 0.07 13.3 0.0 0.18 12.0 0.0 1.6 1 0 0 1 1 1 0 Syncollin VPS9 PF02204.18 EGC38124.1 - 4.3e-24 84.7 1.9 1.2e-23 83.3 1.9 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SKG6 PF08693.10 EGC38125.1 - 0.051 13.0 0.6 0.1 12.0 0.6 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Amnionless PF14828.6 EGC38125.1 - 0.056 12.3 0.3 1.6 7.4 0.1 2.3 2 0 0 2 2 2 0 Amnionless MacB_PCD PF12704.7 EGC38126.1 - 0.041 14.2 3.4 0.65 10.3 0.3 3.1 3 0 0 3 3 3 0 MacB-like periplasmic core domain PhoLip_ATPase_C PF16212.5 EGC38128.1 - 4.9e-70 236.1 24.3 4.9e-70 236.1 24.3 2.3 3 0 0 3 3 3 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC38128.1 - 4e-25 87.3 2.8 4e-25 87.3 2.8 2.3 2 0 0 2 2 2 1 Phospholipid-translocating ATPase N-terminal Cation_ATPase PF13246.6 EGC38128.1 - 2.7e-10 40.2 0.0 2.8e-09 36.9 0.0 2.5 2 0 0 2 2 2 1 Cation transport ATPase (P-type) Hydrolase PF00702.26 EGC38128.1 - 2.8e-10 40.8 0.1 0.00015 22.1 0.0 3.3 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.20 EGC38128.1 - 2.1e-06 27.4 1.0 2.1e-06 27.4 1.0 3.8 4 1 0 4 4 4 1 E1-E2 ATPase Hydrolase_3 PF08282.12 EGC38128.1 - 0.0008 19.2 2.3 0.0094 15.7 0.0 3.1 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase HAD PF12710.7 EGC38128.1 - 0.1 13.0 0.0 1.4 9.3 0.0 2.8 4 0 0 4 4 4 0 haloacid dehalogenase-like hydrolase DUF4342 PF14242.6 EGC38128.1 - 0.11 12.5 2.9 0.27 11.2 0.8 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4342) DUF4231 PF14015.6 EGC38128.1 - 3 8.3 5.0 29 5.2 0.1 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) ASH PF15780.5 EGC38131.1 - 3.7e-05 23.9 4.9 0.008 16.4 0.0 4.8 4 0 0 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin AAA_6 PF12774.7 EGC38132.1 - 4.7e-134 446.5 1.6 1.8e-132 441.3 0.0 4.3 4 1 0 4 4 4 1 Hydrolytic ATP binding site of dynein motor region DHC_N1 PF08385.12 EGC38132.1 - 1.2e-109 367.5 10.9 1.2e-109 367.5 10.9 5.6 6 0 0 6 6 5 1 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.13 EGC38132.1 - 5.3e-107 358.4 11.9 5.3e-107 358.4 11.9 5.7 6 2 0 6 6 5 1 Dynein heavy chain, N-terminal region 2 AAA_9 PF12781.7 EGC38132.1 - 1.1e-73 247.1 0.1 1.1e-73 247.1 0.1 5.8 6 0 0 6 6 5 1 ATP-binding dynein motor region AAA_8 PF12780.7 EGC38132.1 - 1e-70 238.1 0.0 2.9e-69 233.3 0.0 3.0 2 0 0 2 2 2 1 P-loop containing dynein motor region D4 Dynein_C PF18199.1 EGC38132.1 - 1.3e-49 169.1 2.4 6.5e-49 166.8 2.4 2.4 1 0 0 1 1 1 1 Dynein heavy chain C-terminal domain AAA_7 PF12775.7 EGC38132.1 - 2.2e-45 154.4 0.0 6.9e-37 126.7 0.0 4.8 5 0 0 5 5 4 2 P-loop containing dynein motor region MT PF12777.7 EGC38132.1 - 4.3e-41 141.1 13.9 1e-40 139.9 13.9 1.6 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_lid_11 PF18198.1 EGC38132.1 - 8.1e-39 133.1 0.0 2.3e-38 131.6 0.0 1.9 1 0 0 1 1 1 1 Dynein heavy chain AAA lid domain AAA_5 PF07728.14 EGC38132.1 - 1.1e-34 119.3 0.1 6.8e-14 52.0 0.0 6.5 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) Dynein_heavy PF03028.15 EGC38132.1 - 9.1e-27 93.5 0.0 8.7e-26 90.3 0.0 3.0 1 0 0 1 1 1 1 Dynein heavy chain region D6 P-loop domain Dynein_AAA_lid PF17852.1 EGC38132.1 - 7.7e-20 71.3 0.0 6e-19 68.4 0.0 2.8 2 0 0 2 2 1 1 Dynein heavy chain AAA lid domain AAA_22 PF13401.6 EGC38132.1 - 3.1e-14 53.4 0.1 0.0016 18.7 0.0 6.3 5 0 0 5 5 5 3 AAA domain AAA PF00004.29 EGC38132.1 - 1.4e-11 44.9 0.0 0.029 14.8 0.0 5.5 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC38132.1 - 2.3e-08 34.3 0.0 0.17 12.0 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_16 PF13191.6 EGC38132.1 - 1.3e-07 32.1 0.0 2.2 8.6 0.0 6.3 5 0 0 5 5 5 1 AAA ATPase domain AAA_lid_1 PF17857.1 EGC38132.1 - 3.3e-07 30.4 0.1 5e-06 26.7 0.0 2.9 2 0 0 2 2 2 1 AAA+ lid domain AAA_30 PF13604.6 EGC38132.1 - 2.5e-05 24.1 0.1 2.1 8.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain AAA_18 PF13238.6 EGC38132.1 - 5.9e-05 23.6 0.1 19 5.8 0.0 5.3 4 0 0 4 4 4 0 AAA domain AAA_19 PF13245.6 EGC38132.1 - 0.00037 20.9 0.5 0.12 12.7 0.0 4.2 4 0 0 4 4 3 1 AAA domain IstB_IS21 PF01695.17 EGC38132.1 - 0.0015 18.3 2.9 0.36 10.5 0.0 4.4 5 0 0 5 5 4 1 IstB-like ATP binding protein T2SSE PF00437.20 EGC38132.1 - 0.0023 17.1 0.0 0.079 12.0 0.0 2.9 3 0 0 3 3 2 1 Type II/IV secretion system protein Mg_chelatase PF01078.21 EGC38132.1 - 0.0059 16.0 2.6 1.2 8.5 0.0 4.0 5 0 0 5 5 4 1 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGC38132.1 - 0.031 14.0 0.0 18 5.0 0.0 4.2 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.6 EGC38132.1 - 0.036 13.8 0.1 20 5.0 0.0 3.4 3 0 0 3 3 3 0 P-loop containing region of AAA domain RNA_helicase PF00910.22 EGC38132.1 - 0.053 13.9 0.1 1.4e+02 2.9 0.0 5.4 6 0 0 6 6 5 0 RNA helicase AAA_25 PF13481.6 EGC38132.1 - 0.062 12.9 0.3 0.29 10.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain UPF0489 PF12640.7 EGC38132.1 - 0.9 9.7 3.4 1.7 8.9 0.7 2.6 2 0 0 2 2 2 0 UPF0489 domain UPF0147 PF03685.13 EGC38132.1 - 2.5 8.2 10.4 23 5.1 0.0 4.0 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0147) Pentapeptide_3 PF13576.6 EGC38133.1 - 1.2 9.3 9.4 1.6 8.9 1.8 3.8 4 0 0 4 4 4 0 Pentapeptide repeats (9 copies) DUF1495 PF07381.11 EGC38135.1 - 0.019 14.8 0.9 0.96 9.3 0.1 2.8 2 0 0 2 2 2 0 Winged helix DNA-binding domain (DUF1495) DUF3377 PF11857.8 EGC38136.1 - 0.049 13.6 0.9 0.13 12.2 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF3914 PF13053.6 EGC38136.1 - 0.099 13.0 2.3 0.13 12.7 0.5 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3914) DUF4519 PF15012.6 EGC38136.1 - 1.1 9.4 6.6 0.59 10.3 4.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) DUF4834 PF16118.5 EGC38137.1 - 0.0015 19.4 1.8 0.0015 19.4 1.8 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4834) LRR19-TM PF15176.6 EGC38137.1 - 0.006 16.6 1.3 0.023 14.7 0.1 2.4 2 0 0 2 2 2 1 Leucine-rich repeat family 19 TM domain OAD_gamma PF04277.13 EGC38137.1 - 0.029 14.9 0.2 0.029 14.9 0.2 2.0 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain Methyltransf_12 PF08242.12 EGC38137.1 - 2.1 9.1 7.8 4.5 8.1 2.7 3.0 2 1 0 2 2 2 0 Methyltransferase domain Pentapeptide_4 PF13599.6 EGC38138.1 - 4.6 7.5 7.8 1.7 8.8 3.9 2.4 2 1 0 2 2 2 0 Pentapeptide repeats (9 copies) WD40 PF00400.32 EGC38139.1 - 1.5e-27 95.3 23.1 0.00011 22.9 0.3 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat PQQ_3 PF13570.6 EGC38139.1 - 1.5e-07 31.7 4.7 0.82 10.2 0.1 6.2 7 0 0 7 7 6 1 PQQ-like domain zf-RING_UBOX PF13445.6 EGC38139.1 - 2.3e-06 27.5 0.9 2.3e-06 27.5 0.9 2.3 2 0 0 2 2 1 1 RING-type zinc-finger WD40_like PF17005.5 EGC38139.1 - 8.1e-06 25.4 2.7 0.0078 15.6 0.4 2.4 2 0 0 2 2 2 2 WD40-like domain Rootletin PF15035.6 EGC38139.1 - 0.00013 22.0 0.5 0.00022 21.3 0.5 1.3 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-C3HC4_2 PF13923.6 EGC38139.1 - 0.00034 20.4 0.9 0.00034 20.4 0.9 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC38139.1 - 0.0006 19.9 1.1 0.0006 19.9 1.1 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Sina PF03145.16 EGC38139.1 - 0.00071 19.6 9.0 0.0059 16.6 1.4 2.4 1 1 1 2 2 2 1 Seven in absentia protein family zf-C3HC4 PF00097.25 EGC38139.1 - 0.0017 18.2 1.4 0.0017 18.2 1.4 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) Nup160 PF11715.8 EGC38139.1 - 0.0039 15.9 10.3 0.54 8.8 0.0 4.9 5 1 1 6 6 6 1 Nucleoporin Nup120/160 zf-Nse PF11789.8 EGC38139.1 - 0.0046 16.8 0.2 0.0046 16.8 0.2 2.4 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EGC38139.1 - 0.0067 16.4 0.4 0.0067 16.4 0.4 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-TRAF PF02176.18 EGC38139.1 - 0.0095 16.6 9.9 0.026 15.2 9.9 1.8 1 0 0 1 1 1 1 TRAF-type zinc finger CEP63 PF17045.5 EGC38139.1 - 0.016 15.1 3.0 0.026 14.4 3.0 1.2 1 0 0 1 1 1 0 Centrosomal protein of 63 kDa EzrA PF06160.12 EGC38139.1 - 0.023 12.9 4.0 0.031 12.5 4.0 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA ADIP PF11559.8 EGC38139.1 - 0.024 14.7 2.1 0.047 13.8 2.1 1.4 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding Sec3-PIP2_bind PF15277.6 EGC38139.1 - 0.041 14.0 0.0 51 4.1 0.0 3.8 2 1 1 3 3 3 0 Exocyst complex component SEC3 N-terminal PIP2 binding PH Herpes_pp38 PF04846.13 EGC38139.1 - 0.086 12.8 0.2 0.25 11.3 0.2 1.7 1 0 0 1 1 1 0 Herpesvirus pp38 phosphoprotein SPX PF03105.19 EGC38139.1 - 0.12 12.3 8.4 0.22 11.4 8.4 1.4 1 0 0 1 1 1 0 SPX domain Fez1 PF06818.15 EGC38139.1 - 0.16 12.4 1.8 0.27 11.7 1.8 1.3 1 0 0 1 1 1 0 Fez1 zf-TRAF_2 PF15965.5 EGC38139.1 - 0.16 12.4 8.7 0.94 10.0 4.5 3.0 2 1 1 3 3 2 0 TRAF-like zinc-finger Ge1_WD40 PF16529.5 EGC38139.1 - 0.37 9.7 8.1 0.67 8.8 0.0 4.2 3 1 2 5 5 5 0 WD40 region of Ge1, enhancer of mRNA-decapping protein TMF_TATA_bd PF12325.8 EGC38139.1 - 0.45 10.8 3.0 0.97 9.7 3.0 1.5 1 0 0 1 1 1 0 TATA element modulatory factor 1 TATA binding DUF1378 PF07125.11 EGC38139.1 - 0.74 10.0 3.0 20 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1378) TolA_bind_tri PF16331.5 EGC38139.1 - 0.98 9.5 5.3 0.62 10.2 1.6 2.2 1 1 1 2 2 2 0 TolA binding protein trimerisation zf-RING_2 PF13639.6 EGC38139.1 - 7.6 7.0 10.0 0.35 11.3 0.8 3.2 2 0 0 2 2 2 0 Ring finger domain 3Beta_HSD PF01073.19 EGC38141.1 - 6.9e-30 104.0 0.0 8.8e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC38141.1 - 3.8e-24 85.5 0.0 5e-24 85.1 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.12 EGC38141.1 - 2.3e-17 63.0 0.0 7.9e-09 35.1 0.0 2.3 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.6 EGC38141.1 - 4.2e-14 52.8 0.0 5.7e-14 52.4 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding GDP_Man_Dehyd PF16363.5 EGC38141.1 - 9.9e-11 41.6 0.1 2.5e-09 37.0 0.0 2.3 2 1 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGC38141.1 - 1.5e-10 41.0 0.0 2.2e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.17 EGC38141.1 - 2.6e-10 39.9 0.0 3.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC38141.1 - 1.2e-06 27.9 0.0 4.6e-06 26.0 0.1 1.8 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein KR PF08659.10 EGC38141.1 - 7.9e-05 22.6 0.1 0.00018 21.5 0.1 1.5 1 1 0 1 1 1 1 KR domain adh_short PF00106.25 EGC38141.1 - 0.00032 20.2 0.0 0.00053 19.5 0.0 1.4 1 1 0 1 1 1 1 short chain dehydrogenase Sacchrp_dh_NADP PF03435.18 EGC38141.1 - 0.0013 19.0 0.0 0.0021 18.3 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGC38141.1 - 0.0072 16.9 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.20 EGC38141.1 - 0.026 14.6 0.0 0.05 13.7 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase ELFV_dehydrog PF00208.21 EGC38141.1 - 0.043 13.5 0.4 0.26 11.0 0.3 2.1 1 1 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.18 EGC38141.1 - 0.047 14.0 0.0 0.067 13.5 0.0 1.2 1 0 0 1 1 1 0 TrkA-N domain NAD_binding_2 PF03446.15 EGC38141.1 - 0.07 13.3 0.0 0.13 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DpaA_N PF16924.5 EGC38141.1 - 0.07 13.2 0.0 0.13 12.4 0.0 1.5 1 0 0 1 1 1 0 Dipicolinate synthase subunit A N-terminal domain PH PF00169.29 EGC38142.1 - 2.2e-25 89.2 0.7 1.9e-14 54.0 0.1 3.1 2 0 0 2 2 2 2 PH domain TPR_19 PF14559.6 EGC38142.1 - 1.6e-08 34.9 0.3 0.00017 22.0 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC38142.1 - 1.5e-07 31.0 2.4 0.049 13.8 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat C2 PF00168.30 EGC38142.1 - 1.5e-07 31.6 0.4 4.8e-06 26.8 0.2 3.1 2 1 0 2 2 2 1 C2 domain PH_3 PF14593.6 EGC38142.1 - 2e-07 31.1 2.4 4.3e-05 23.5 0.1 3.5 2 1 0 2 2 2 1 PH domain TPR_11 PF13414.6 EGC38142.1 - 3.3e-07 29.9 1.3 0.0042 16.7 0.1 2.6 2 0 0 2 2 2 2 TPR repeat PH_11 PF15413.6 EGC38142.1 - 4.8e-06 26.9 5.3 0.00028 21.3 0.0 4.0 3 0 0 3 3 3 1 Pleckstrin homology domain TPR_1 PF00515.28 EGC38142.1 - 1.6e-05 24.5 8.3 0.029 14.2 0.4 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PH_9 PF15410.6 EGC38142.1 - 0.00077 19.8 0.3 0.0035 17.7 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_16 PF13432.6 EGC38142.1 - 0.0041 17.7 0.1 0.92 10.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC38142.1 - 0.018 15.8 0.0 26 6.0 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat She9_MDM33 PF05546.11 EGC38142.1 - 0.047 13.5 1.0 0.18 11.6 0.1 2.3 2 0 0 2 2 2 0 She9 / Mdm33 family TPR_8 PF13181.6 EGC38142.1 - 0.089 13.1 7.5 3.9 7.9 0.1 4.9 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC38142.1 - 0.091 13.1 0.4 3.1 8.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Menin PF05053.13 EGC38142.1 - 0.53 8.6 12.9 1.1 7.5 12.9 1.6 1 0 0 1 1 1 0 Menin TMEM43 PF07787.12 EGC38143.1 - 0.03 13.7 0.0 0.043 13.2 0.0 1.2 1 0 0 1 1 1 0 Transmembrane protein 43 PQQ_3 PF13570.6 EGC38143.1 - 0.089 13.3 3.6 6.7 7.3 0.1 4.2 4 0 0 4 4 4 0 PQQ-like domain SBBP PF06739.11 EGC38143.1 - 3.6 7.7 12.6 0.26 11.3 2.9 3.1 3 0 0 3 3 3 0 Beta-propeller repeat ABM PF03992.16 EGC38144.1 - 6.5e-15 55.0 0.0 8e-15 54.7 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Acetyltransf_10 PF13673.7 EGC38145.1 - 1.8e-13 50.5 0.0 3.1e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC38145.1 - 2.4e-08 34.3 0.1 3.7e-08 33.7 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC38145.1 - 1.5e-07 31.7 0.0 2e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.6 EGC38145.1 - 2.5e-06 28.1 0.0 0.00015 22.4 0.0 2.5 2 1 1 3 3 3 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC38145.1 - 0.0012 18.8 0.0 0.0028 17.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_15 PF17013.5 EGC38145.1 - 0.019 14.5 2.1 0.029 13.9 2.1 1.4 1 1 0 1 1 1 0 Putative acetyl-transferase Acetyltransf_CG PF14542.6 EGC38145.1 - 0.042 14.0 0.0 0.082 13.0 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Autoind_synth PF00765.17 EGC38145.1 - 0.055 13.0 0.0 0.086 12.4 0.0 1.3 1 0 0 1 1 1 0 Autoinducer synthase TPR_1 PF00515.28 EGC38146.1 - 1.1e-10 40.9 8.9 6.1e-06 25.8 0.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.17 EGC38146.1 - 2.6e-09 36.5 9.4 2.4e-05 24.1 0.2 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC38146.1 - 2.2e-06 28.0 2.0 0.12 13.1 0.0 4.3 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38146.1 - 1.2e-05 25.1 7.9 0.047 13.9 0.1 4.4 5 0 0 5 5 4 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC38146.1 - 4.3e-05 23.6 2.7 0.0078 16.4 0.3 3.1 2 1 1 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.6 EGC38146.1 - 0.00014 22.3 0.1 0.0004 20.8 0.1 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC38146.1 - 0.00084 19.0 2.0 0.71 9.6 0.0 3.8 2 1 1 3 3 3 2 TPR repeat TPR_9 PF13371.6 EGC38146.1 - 0.00094 19.3 0.0 0.0019 18.3 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC38146.1 - 0.0021 18.7 0.1 0.011 16.4 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.6 EGC38146.1 - 0.0027 17.9 1.2 0.089 13.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC38146.1 - 0.0061 16.6 0.1 0.031 14.3 0.0 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.14 EGC38146.1 - 0.0092 15.4 1.5 0.02 14.3 0.1 2.3 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_12 PF13424.6 EGC38146.1 - 0.016 15.5 4.0 0.032 14.5 0.2 3.2 3 1 0 3 3 3 0 Tetratricopeptide repeat Mrpl_C PF18502.1 EGC38146.1 - 0.049 13.9 2.8 0.055 13.7 0.7 2.3 2 0 0 2 2 2 0 54S ribosomal protein L8 C-terminal domain Alkyl_sulf_dimr PF14863.6 EGC38146.1 - 0.21 12.1 1.7 7.3 7.0 0.0 3.2 3 1 0 3 3 2 0 Alkyl sulfatase dimerisation tRNA-synt_2c PF01411.19 EGC38151.1 - 1.6e-210 700.4 0.0 2.2e-210 699.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) DHHA1 PF02272.19 EGC38151.1 - 2.4e-15 57.2 1.0 2.4e-15 57.2 1.0 2.3 2 0 0 2 2 2 1 DHHA1 domain tRNA_SAD PF07973.14 EGC38151.1 - 6.5e-15 54.9 0.0 1.8e-14 53.5 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Mis12 PF05859.12 EGC38151.1 - 0.035 14.2 0.1 0.11 12.6 0.1 1.8 1 0 0 1 1 1 0 Mis12 protein zf-C3HC4_3 PF13920.6 EGC38152.1 - 2.4e-09 36.9 7.4 4.7e-09 36.0 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38152.1 - 3.8e-09 36.7 9.5 8.9e-09 35.6 9.5 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC38152.1 - 3.3e-08 33.2 9.0 6e-08 32.4 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38152.1 - 4.2e-07 29.7 11.2 1.2e-06 28.2 11.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC38152.1 - 2.5e-05 24.2 5.1 5.5e-05 23.1 5.1 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38152.1 - 2.6e-05 24.1 8.3 2.6e-05 24.1 8.3 1.9 2 0 0 2 2 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC38152.1 - 0.0002 21.1 6.7 0.00046 20.0 6.7 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC38152.1 - 0.00044 20.0 9.8 0.001 18.8 9.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGC38152.1 - 0.00093 18.9 7.2 0.0029 17.3 7.2 1.8 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC38152.1 - 0.0019 18.4 7.8 0.0065 16.7 7.8 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain DUF4834 PF16118.5 EGC38152.1 - 0.0035 18.3 2.8 0.0035 18.3 2.8 4.8 3 1 2 5 5 2 1 Domain of unknown function (DUF4834) zf-C3HC4_4 PF15227.6 EGC38152.1 - 0.0073 16.4 7.2 0.024 14.8 7.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC38152.1 - 0.14 12.1 2.4 0.26 11.2 2.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF948 PF06103.11 EGC38153.1 - 0.57 10.5 15.6 0.65 10.3 12.2 2.7 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HemY_N PF07219.13 EGC38153.1 - 3 8.1 0.0 3 8.1 0.0 3.3 3 1 0 3 3 3 0 HemY protein N-terminus EGF_2 PF07974.13 EGC38154.1 - 0.00028 21.2 7.3 0.00028 21.2 7.3 1.7 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.24 EGC38154.1 - 0.0037 17.4 7.7 0.0087 16.2 7.7 1.6 1 0 0 1 1 1 1 Laminin EGF domain EGF_Tenascin PF18720.1 EGC38154.1 - 0.013 15.5 4.6 0.025 14.6 4.6 1.4 1 0 0 1 1 1 0 Tenascin EGF domain EGF_alliinase PF04863.13 EGC38154.1 - 0.17 12.3 4.5 0.34 11.3 4.5 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain Pal1 PF08316.11 EGC38155.1 - 0.33 11.7 8.4 0.42 11.4 8.4 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein DUF5308 PF17233.2 EGC38155.1 - 0.52 10.5 3.1 0.6 10.3 3.1 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5308) DDHD PF02862.17 EGC38155.1 - 2.8 8.1 14.5 3.1 7.9 14.5 1.1 1 0 0 1 1 1 0 DDHD domain Acetyltransf_1 PF00583.25 EGC38157.1 - 1.7e-14 54.1 0.0 2e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC38157.1 - 1.2e-07 32.1 0.1 1.8e-07 31.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC38157.1 - 8.1e-07 29.0 0.0 1.1e-06 28.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GSIII_N PF12437.8 EGC38158.1 - 5.9e-69 230.8 0.0 1.1e-68 229.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C-ter PF18318.1 EGC38158.1 - 9.5e-40 135.1 0.1 2.1e-39 134.0 0.1 1.6 1 0 0 1 1 1 1 Glutamine synthetase C-terminal domain Gln-synt_C PF00120.24 EGC38158.1 - 5.2e-21 75.0 0.0 9e-21 74.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain S6PP PF05116.13 EGC38158.1 - 0.094 12.2 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase MucBP PF06458.12 EGC38159.1 - 0.024 15.6 0.1 0.024 15.6 0.1 4.0 3 0 0 3 3 3 0 MucBP domain DUF751 PF05421.11 EGC38159.1 - 0.66 10.7 5.1 5.7 7.7 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF751) ATP1G1_PLM_MAT8 PF02038.16 EGC38159.1 - 1.1 8.8 3.2 3.5 7.2 3.2 1.8 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family RhoGAP PF00620.27 EGC38160.1 - 1.9e-29 102.5 0.1 3.7e-29 101.5 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain ASH PF15780.5 EGC38160.1 - 0.0052 17.0 0.4 0.015 15.5 0.4 1.8 1 1 0 1 1 1 1 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin Motile_Sperm PF00635.26 EGC38160.1 - 0.0099 15.7 1.0 0.029 14.2 0.8 1.8 2 0 0 2 2 2 1 MSP (Major sperm protein) domain Maf1 PF09174.10 EGC38161.1 - 2.1e-62 210.4 2.7 2.5e-62 210.1 2.7 1.1 1 0 0 1 1 1 1 Maf1 regulator SPRY PF00622.28 EGC38162.1 - 8.1e-13 48.5 1.7 1.8e-12 47.4 1.7 1.6 1 0 0 1 1 1 1 SPRY domain F-box-like PF12937.7 EGC38162.1 - 8.2e-06 25.6 0.0 1.5e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box_4 PF15966.5 EGC38162.1 - 0.00055 19.8 0.1 0.0012 18.7 0.1 1.6 1 0 0 1 1 1 1 F-box F-box PF00646.33 EGC38162.1 - 0.0039 17.0 0.1 0.0087 15.9 0.1 1.5 1 0 0 1 1 1 1 F-box domain Neuralized PF07177.12 EGC38162.1 - 0.082 12.9 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Neuralized NOA36 PF06524.12 EGC38163.1 - 2.5 7.4 10.4 3.7 6.8 10.4 1.2 1 0 0 1 1 1 0 NOA36 protein LRR_4 PF12799.7 EGC38164.1 - 8e-10 38.8 26.1 0.0002 21.6 1.5 7.1 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC38164.1 - 2e-08 33.9 15.6 5.9e-06 26.0 1.5 4.3 2 1 2 4 4 4 3 Leucine rich repeat LRR_9 PF14580.6 EGC38164.1 - 4.1e-07 29.7 5.4 3.4e-06 26.7 4.7 2.4 1 1 1 2 2 2 2 Leucine-rich repeat LRR_6 PF13516.6 EGC38164.1 - 0.00023 21.0 12.0 1.2 9.4 0.1 5.7 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.33 EGC38164.1 - 5.2 8.0 15.5 22 6.1 0.2 7.1 4 2 0 4 4 4 0 Leucine Rich Repeat PRY PF13765.6 EGC38165.1 - 0.024 14.3 1.2 11 5.7 0.0 3.1 2 1 1 3 3 3 0 SPRY-associated domain PRY PF13765.6 EGC38166.1 - 0.037 13.7 0.0 9.8 5.9 0.0 2.6 3 0 0 3 3 3 0 SPRY-associated domain DDE_3 PF13358.6 EGC38167.1 - 7.1e-09 35.6 0.3 7.1e-09 35.6 0.3 1.5 2 0 0 2 2 2 1 DDE superfamily endonuclease GST_N_3 PF13417.6 EGC38168.1 - 7.7e-14 51.9 0.0 1.3e-13 51.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.20 EGC38168.1 - 5.5e-13 49.1 0.1 9.8e-13 48.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC38168.1 - 1.2e-10 41.6 0.0 1.8e-10 40.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.24 EGC38168.1 - 0.044 14.0 0.0 0.1 12.8 0.0 1.6 1 0 0 1 1 1 0 Glutaredoxin Josephin PF02099.17 EGC38170.1 - 0.19 11.8 5.6 0.29 11.2 5.6 1.4 1 1 0 1 1 1 0 Josephin AMP-binding PF00501.28 EGC38171.1 - 7.2e-82 275.2 0.0 9.4e-82 274.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC38171.1 - 2.5e-21 76.5 0.0 4.4e-21 75.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC38171.1 - 1.7e-14 53.4 1.8 3.4e-14 52.5 1.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus EVE PF01878.18 EGC38171.1 - 0.15 12.1 0.0 0.35 10.9 0.0 1.6 1 0 0 1 1 1 0 EVE domain AMP-binding PF00501.28 EGC38172.1 - 5.8e-79 265.7 0.0 7.1e-79 265.4 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC38172.1 - 1.4e-19 70.8 0.0 2.4e-19 70.1 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ACAS_N PF16177.5 EGC38172.1 - 5e-14 52.0 4.3 1.2e-13 50.7 4.3 1.7 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus PLDc_2 PF13091.6 EGC38173.1 - 9.8e-17 61.1 0.6 4e-10 39.7 0.1 3.0 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.22 EGC38173.1 - 1.4e-14 53.6 1.1 1.6e-06 28.0 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PH PF00169.29 EGC38173.1 - 0.00049 20.6 0.2 0.00049 20.6 0.2 2.1 2 0 0 2 2 2 1 PH domain EF-hand_7 PF13499.6 EGC38173.1 - 0.0087 16.5 0.9 0.0087 16.5 0.9 3.7 3 1 1 4 4 4 1 EF-hand domain pair EF-hand_1 PF00036.32 EGC38173.1 - 0.013 15.0 0.2 0.093 12.3 0.0 2.7 2 0 0 2 2 2 0 EF hand EF-hand_6 PF13405.6 EGC38173.1 - 0.018 14.9 0.5 0.45 10.6 0.0 3.5 3 0 0 3 3 3 0 EF-hand domain EF-hand_8 PF13833.6 EGC38173.1 - 0.063 13.1 0.1 0.36 10.7 0.1 2.4 1 1 0 1 1 1 0 EF-hand domain pair DUF572 PF04502.13 EGC38174.1 - 2.1e-73 247.8 19.7 2.3e-73 247.7 19.7 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) DNA_RNApol_7kD PF03604.13 EGC38174.1 - 0.051 13.3 1.1 9.5 6.0 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit D5_N PF08706.11 EGC38174.1 - 0.056 13.7 1.9 0.12 12.6 1.9 1.6 1 0 0 1 1 1 0 D5 N terminal like DUF2870 PF11069.8 EGC38174.1 - 0.058 13.8 2.6 0.058 13.8 2.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF2870) LIM PF00412.22 EGC38174.1 - 0.063 13.5 0.5 9.4 6.6 0.0 2.5 2 0 0 2 2 2 0 LIM domain E6 PF00518.17 EGC38174.1 - 0.081 13.4 4.3 3.4 8.2 0.0 3.0 1 1 2 3 3 3 0 Early Protein (E6) TF_Zn_Ribbon PF08271.12 EGC38174.1 - 0.11 12.1 0.4 0.11 12.1 0.4 2.5 3 0 0 3 3 3 0 TFIIB zinc-binding DUF3752 PF12572.8 EGC38174.1 - 0.19 12.2 11.0 0.33 11.5 11.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3752) Yippee-Mis18 PF03226.14 EGC38174.1 - 0.26 11.5 2.4 6.6 7.0 0.0 2.9 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zf-PHD-like PF15446.6 EGC38174.1 - 0.36 10.4 7.6 0.34 10.5 4.5 2.2 1 1 1 2 2 2 0 PHD/FYVE-zinc-finger like domain Zn_ribbon_recom PF13408.6 EGC38174.1 - 0.44 11.1 5.3 1.2 9.8 0.3 2.3 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain zf-Sec23_Sec24 PF04810.15 EGC38174.1 - 0.88 9.7 3.3 23 5.1 0.1 2.6 2 1 0 2 2 2 0 Sec23/Sec24 zinc finger RNA_pol_N PF01194.17 EGC38174.1 - 1.1 9.7 5.3 5.3 7.4 0.2 3.1 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit Yos1 PF08571.10 EGC38175.1 - 1.8e-12 47.3 0.9 2.1e-12 47.1 0.9 1.1 1 0 0 1 1 1 1 Yos1-like Ras PF00071.22 EGC38176.1 - 1.2e-28 99.7 0.0 1.6e-28 99.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38176.1 - 2.2e-21 76.3 0.0 6.3e-21 74.8 0.1 1.7 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38176.1 - 1.5e-05 24.5 0.6 2.4e-05 23.9 0.6 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC38176.1 - 0.083 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_7 PF12775.7 EGC38176.1 - 0.13 11.7 0.1 0.22 11.0 0.1 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region HEAT PF02985.22 EGC38177.1 - 3.8e-44 144.9 25.5 0.0012 18.9 0.0 23.3 27 0 0 27 27 27 8 HEAT repeat HEAT_2 PF13646.6 EGC38177.1 - 9.4e-35 118.9 0.5 1.4e-05 25.4 0.0 13.9 9 5 7 17 17 16 8 HEAT repeats HEAT_EZ PF13513.6 EGC38177.1 - 2.4e-30 104.5 12.4 0.00012 22.5 0.0 17.3 16 3 4 20 20 19 6 HEAT-like repeat Vac14_Fab1_bd PF12755.7 EGC38177.1 - 1.4e-18 67.3 0.4 0.16 12.6 0.0 10.7 10 0 0 10 10 10 4 Vacuolar 14 Fab1-binding region CLASP_N PF12348.8 EGC38177.1 - 2.3e-15 56.8 9.8 4.5e-05 23.1 0.0 7.5 6 0 0 6 6 6 3 CLASP N terminal Cnd1 PF12717.7 EGC38177.1 - 1e-13 51.6 42.3 0.0054 16.8 0.0 14.6 9 5 7 18 18 18 4 non-SMC mitotic condensation complex subunit 1 Condensin2nSMC PF12422.8 EGC38177.1 - 2.3e-07 31.1 7.3 2.3 8.4 0.0 9.0 8 1 1 9 9 9 2 Condensin II non structural maintenance of chromosomes subunit ParcG PF10274.9 EGC38177.1 - 4.4e-06 26.9 21.7 8 6.5 0.0 10.0 9 2 3 12 12 12 1 Parkin co-regulated protein Arm PF00514.23 EGC38177.1 - 1.6e-05 24.7 10.9 0.51 10.5 0.0 7.6 8 0 0 8 8 6 2 Armadillo/beta-catenin-like repeat TAF6_C PF07571.13 EGC38177.1 - 0.00013 22.3 3.8 7.2 7.0 0.0 6.7 6 0 0 6 6 6 1 TAF6 C-terminal HEAT repeat domain UME PF08064.13 EGC38177.1 - 0.0024 17.7 19.4 0.2 11.6 0.0 8.2 9 1 0 9 9 9 2 UME (NUC010) domain DUF3437 PF11919.8 EGC38177.1 - 0.024 14.6 4.3 4.3 7.3 0.0 5.9 7 0 0 7 7 6 0 Domain of unknown function (DUF3437) RTP1_C1 PF10363.9 EGC38177.1 - 0.25 11.5 5.4 15 5.8 0.1 5.9 5 0 0 5 5 5 0 Required for nuclear transport of RNA pol II C-terminus 1 HEAT_PBS PF03130.16 EGC38177.1 - 6.1 7.8 13.5 43 5.2 0.0 7.4 10 0 0 10 10 7 0 PBS lyase HEAT-like repeat DUF1878 PF08963.10 EGC38177.1 - 6.6 7.3 9.1 13 6.4 0.3 4.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1878) p450 PF00067.22 EGC38179.1 - 5.7e-78 262.7 1.7 8.3e-78 262.2 1.7 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arm PF00514.23 EGC38179.1 - 3.5e-11 42.7 5.1 0.00028 20.8 0.5 3.6 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.6 EGC38179.1 - 0.0003 21.2 0.1 0.016 15.7 0.0 2.8 3 0 0 3 3 3 1 HEAT-like repeat DUF4894 PF16235.5 EGC38179.1 - 0.012 16.0 0.5 0.012 16.0 0.5 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4894) HEAT PF02985.22 EGC38179.1 - 0.058 13.7 0.5 15 6.2 0.0 3.6 3 0 0 3 3 3 0 HEAT repeat USP8_dimer PF08969.11 EGC38180.1 - 0.23 11.7 7.1 0.47 10.7 6.9 1.6 1 1 0 1 1 1 0 USP8 dimerisation domain TACC_C PF05010.14 EGC38181.1 - 1.9e-05 24.5 24.1 0.0018 18.1 10.1 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal PikAIV_N PF18605.1 EGC38181.1 - 0.014 15.0 1.7 0.042 13.4 1.7 1.9 1 0 0 1 1 1 0 Narbonolide/10-deoxymethynolide synthase PikA4 N-terminal domain DUF4446 PF14584.6 EGC38181.1 - 1.6 8.7 16.7 0.46 10.5 5.4 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Telomerase_RBD PF12009.8 EGC38181.1 - 3.3 7.8 11.2 0.15 12.2 1.1 2.6 1 1 1 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain RIC1 PF07064.13 EGC38182.1 - 4.4e-67 226.1 0.0 8.6e-67 225.2 0.0 1.5 1 0 0 1 1 1 1 RIC1 ANAPC4_WD40 PF12894.7 EGC38182.1 - 0.012 15.9 0.4 0.68 10.3 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain Ank_4 PF13637.6 EGC38183.1 - 4.5e-29 100.4 3.7 2.2e-07 31.3 0.0 7.5 7 0 0 7 7 7 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC38183.1 - 9e-28 96.7 4.7 5.1e-08 33.4 0.1 6.6 5 1 0 6 6 6 4 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC38183.1 - 6.7e-24 81.4 5.9 0.0016 18.8 0.0 9.5 9 0 0 9 9 9 5 Ankyrin repeat Ank_5 PF13857.6 EGC38183.1 - 1.9e-20 72.7 2.8 4.7e-05 23.6 0.0 6.2 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.30 EGC38183.1 - 1.7e-18 66.1 9.5 0.039 14.4 0.1 8.9 7 2 0 7 7 7 5 Ankyrin repeat Casc1_N PF15927.5 EGC38183.1 - 0.007 16.1 6.2 0.011 15.4 0.0 3.7 3 1 0 3 3 3 1 Cancer susceptibility candidate 1 N-terminus FAM110_C PF14160.6 EGC38183.1 - 0.071 14.2 3.6 0.1 13.7 0.3 2.8 3 0 0 3 3 3 0 Centrosome-associated C terminus SR-25 PF10500.9 EGC38183.1 - 0.072 12.7 8.6 0.14 11.7 8.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Img2 PF05046.14 EGC38183.1 - 0.082 13.2 0.2 0.68 10.3 0.0 2.5 2 0 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) DUF3446 PF11928.8 EGC38183.1 - 0.27 11.6 14.1 0.15 12.4 9.6 2.4 2 0 0 2 2 2 0 Early growth response N-terminal domain bZIP_1 PF00170.21 EGC38185.1 - 2.7e-13 49.8 6.7 2.7e-13 49.8 6.7 2.3 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC38185.1 - 8.8e-11 41.7 6.2 3.3e-10 39.9 6.2 2.0 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGC38185.1 - 0.00054 20.4 4.5 0.00054 20.4 4.5 3.2 2 1 1 3 3 3 1 bZIP Maf transcription factor GIT_CC PF16559.5 EGC38185.1 - 0.0057 16.5 0.6 0.0057 16.5 0.6 3.5 3 0 0 3 3 3 1 GIT coiled-coil Rho guanine nucleotide exchange factor Adap_comp_sub PF00928.21 EGC38186.1 - 8.8e-77 258.0 0.4 1.1e-76 257.8 0.4 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.20 EGC38186.1 - 0.0003 20.7 0.2 0.00055 19.9 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Methyltransf_11 PF08241.12 EGC38187.1 - 5.9e-17 62.1 0.0 3.6e-16 59.6 0.0 2.3 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38187.1 - 1.1e-13 51.7 0.0 9.5e-13 48.7 0.0 2.3 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC38187.1 - 1.6e-10 41.6 0.2 5.4e-10 39.9 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38187.1 - 3.2e-10 40.1 0.1 6.3e-10 39.1 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38187.1 - 6.3e-08 32.6 0.0 1.2e-07 31.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC38187.1 - 4.2e-07 29.5 0.0 7.7e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.19 EGC38187.1 - 3.9e-05 23.8 0.0 6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_8 PF05148.15 EGC38187.1 - 0.0007 19.5 0.0 0.0014 18.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.12 EGC38187.1 - 0.003 16.7 0.4 0.21 10.6 0.0 2.7 2 1 0 2 2 2 1 DREV methyltransferase PCMT PF01135.19 EGC38187.1 - 0.0089 15.8 0.0 0.013 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 EGC38187.1 - 0.039 13.5 0.0 0.087 12.3 0.0 1.6 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase DUF4972 PF16342.5 EGC38187.1 - 0.078 12.7 1.0 4 7.1 0.1 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4972) DUF4064 PF13273.6 EGC38188.1 - 0.46 10.8 1.8 0.5 10.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Mhr1 PF12829.7 EGC38189.1 - 0.031 14.4 0.3 0.045 13.8 0.3 1.3 1 0 0 1 1 1 0 Transcriptional regulation of mitochondrial recombination SARAF PF06682.12 EGC38190.1 - 0.0021 17.8 10.1 0.0021 17.8 10.1 2.1 1 1 1 2 2 2 1 SOCE-associated regulatory factor of calcium homoeostasis CRA PF06589.11 EGC38190.1 - 0.013 15.6 0.8 0.013 15.6 0.8 2.3 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) Ac76 PF05814.11 EGC38190.1 - 0.19 11.7 0.4 0.52 10.4 0.4 1.7 1 0 0 1 1 1 0 Orf76 (Ac76) Comm PF15957.5 EGC38190.1 - 1.5 9.2 21.1 0.032 14.6 8.5 2.4 1 1 2 3 3 3 0 Commissureless SID-1_RNA_chan PF13965.6 EGC38190.1 - 1.5 7.1 19.5 0.071 11.5 4.6 2.0 1 1 1 2 2 2 0 dsRNA-gated channel SID-1 MutS_V PF00488.21 EGC38193.1 - 2.5e-81 272.2 0.2 2.5e-81 272.2 0.2 1.7 2 0 0 2 2 2 1 MutS domain V MutS_I PF01624.20 EGC38193.1 - 1.7e-35 121.7 0.0 3.7e-35 120.6 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_III PF05192.18 EGC38193.1 - 4.2e-31 108.7 4.2 4.2e-31 108.7 4.2 2.6 3 1 0 3 3 3 1 MutS domain III MutS_IV PF05190.18 EGC38193.1 - 3.4e-17 62.6 2.0 3.4e-17 62.6 2.0 2.6 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.17 EGC38193.1 - 1.2e-15 58.0 0.1 3.1e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 MutS domain II PA28_alpha PF02251.18 EGC38193.1 - 0.039 14.0 0.3 0.2 11.8 0.3 2.2 1 0 0 1 1 1 0 Proteasome activator pa28 alpha subunit Gp-FAR-1 PF05823.12 EGC38193.1 - 1.4 9.2 7.3 0.54 10.6 0.4 3.3 4 0 0 4 4 4 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) PRA1 PF03208.19 EGC38194.1 - 3.6e-12 46.1 0.1 4.7e-12 45.7 0.1 1.1 1 0 0 1 1 1 1 PRA1 family protein bZIP_1 PF00170.21 EGC38196.1 - 1.3e-08 34.8 8.8 1.3e-08 34.8 8.8 2.1 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC38196.1 - 6.8e-07 29.3 9.7 1.2e-05 25.3 6.1 2.6 1 1 1 2 2 2 2 Basic region leucine zipper bZIP_Maf PF03131.17 EGC38196.1 - 0.0066 16.9 6.8 0.016 15.7 6.8 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor V_ATPase_I PF01496.19 EGC38196.1 - 0.09 10.7 11.3 0.11 10.5 11.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family BT1 PF03092.16 EGC38196.1 - 0.16 10.2 1.4 0.22 9.7 1.4 1.1 1 0 0 1 1 1 0 BT1 family APG6_N PF17675.1 EGC38196.1 - 0.28 11.7 6.8 0.54 10.8 6.8 1.4 1 0 0 1 1 1 0 Apg6 coiled-coil region DUF5588 PF17826.1 EGC38196.1 - 0.53 9.1 9.1 0.26 10.2 0.2 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5588) Pkinase PF00069.25 EGC38197.1 - 1.2e-71 241.1 1.7 2.9e-71 239.9 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38197.1 - 4.2e-37 127.8 0.0 8.1e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC38197.1 - 3e-09 36.6 0.0 6e-09 35.6 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC38197.1 - 2.9e-05 23.5 0.0 5.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC38197.1 - 0.0033 17.4 0.0 0.01 15.7 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGC38197.1 - 0.04 13.4 0.1 0.15 11.6 0.0 2.0 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL RRM_1 PF00076.22 EGC38198.1 - 2.4e-40 136.2 2.1 4.3e-17 61.7 0.3 3.8 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.27 EGC38198.1 - 1.9e-13 49.8 5.1 3e-12 46.0 1.1 2.9 3 0 0 3 3 3 2 SAP domain RRM_5 PF13893.6 EGC38198.1 - 1e-06 28.4 0.1 0.062 12.9 0.0 3.7 1 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC38198.1 - 6.5e-06 25.9 0.0 1.8 8.5 0.0 4.0 3 0 0 3 3 3 3 Occluded RNA-recognition motif RRM_7 PF16367.5 EGC38198.1 - 0.01 16.0 0.0 0.83 9.8 0.0 3.4 2 0 0 2 2 2 0 RNA recognition motif Peptidase_S9 PF00326.21 EGC38200.1 - 1e-24 87.2 0.0 1.8e-24 86.4 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.20 EGC38200.1 - 5e-09 36.2 0.2 8.8e-06 25.5 0.2 2.6 2 0 0 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.11 EGC38200.1 - 1.1e-06 28.7 0.1 5.9e-06 26.4 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Hydrolase_4 PF12146.8 EGC38200.1 - 1.2e-05 24.7 0.0 0.013 14.8 0.0 2.5 2 1 0 3 3 3 2 Serine aminopeptidase, S33 PD40 PF07676.12 EGC38200.1 - 0.00038 20.3 0.0 0.0044 16.9 0.0 2.7 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat AXE1 PF05448.12 EGC38200.1 - 0.0025 16.5 0.0 0.029 13.1 0.0 2.5 2 0 0 2 2 2 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.7 EGC38200.1 - 0.0045 17.6 0.0 0.007 17.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.18 EGC38200.1 - 0.0047 16.5 0.0 0.032 13.8 0.0 2.1 2 0 0 2 2 2 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.13 EGC38200.1 - 0.0052 16.7 0.0 0.018 14.9 0.0 1.9 2 0 0 2 2 2 1 alpha/beta hydrolase fold COesterase PF00135.28 EGC38200.1 - 0.016 14.1 0.0 0.029 13.3 0.0 1.4 1 0 0 1 1 1 0 Carboxylesterase family TetR_C_4 PF08359.11 EGC38201.1 - 0.1 12.7 2.7 0.21 11.7 0.2 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Ku_PK_bind PF08785.11 EGC38201.1 - 0.11 12.7 4.9 0.064 13.4 2.5 2.0 2 0 0 2 2 2 0 Ku C terminal domain like DUF1840 PF08895.11 EGC38201.1 - 0.54 10.6 3.6 1.8 9.0 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Syntaxin-6_N PF09177.11 EGC38201.1 - 1.8 9.2 10.6 0.14 12.7 2.4 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2115 PF09888.9 EGC38201.1 - 6.1 7.3 11.1 0.52 10.8 2.8 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) CLN5 PF15014.6 EGC38202.1 - 1.5e-05 24.9 2.3 1.7e-05 24.6 2.3 1.1 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 zf-CHY PF05495.12 EGC38203.1 - 3.7e-19 69.0 24.8 3.7e-19 69.0 24.8 3.9 2 1 2 4 4 4 2 CHY zinc finger zinc_ribbon_6 PF14599.6 EGC38203.1 - 1.4e-18 66.7 0.2 1.4e-18 66.7 0.2 3.7 3 0 0 3 3 3 1 Zinc-ribbon zf-RING_2 PF13639.6 EGC38203.1 - 4e-09 36.7 5.1 4e-09 36.7 5.1 5.5 3 1 3 6 6 6 1 Ring finger domain zf-C3HC4 PF00097.25 EGC38203.1 - 3.3e-07 30.1 5.2 3.3e-07 30.1 5.2 5.9 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38203.1 - 3e-06 27.0 5.3 3e-06 27.0 5.3 5.5 4 2 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC38203.1 - 5.5e-06 26.3 4.4 5.5e-06 26.3 4.4 5.7 4 2 1 5 5 5 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC38203.1 - 0.00016 21.4 4.9 0.00016 21.4 4.9 5.4 4 2 1 5 5 5 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGC38203.1 - 0.0002 21.0 1.8 0.0002 21.0 1.8 3.7 5 0 0 5 5 5 1 RING-like zinc finger zf-RING_UBOX PF13445.6 EGC38203.1 - 0.00027 20.9 0.9 0.00027 20.9 0.9 4.5 3 2 1 4 4 4 1 RING-type zinc-finger zf-C2H2_6 PF13912.6 EGC38203.1 - 0.43 10.7 0.1 0.43 10.7 0.1 5.4 5 1 1 6 6 6 0 C2H2-type zinc finger 2-oxoacid_dh PF00198.23 EGC38204.1 - 8.8e-80 267.5 0.0 1.6e-79 266.7 0.0 1.4 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGC38204.1 - 8.6e-18 63.9 0.1 2e-17 62.8 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.17 EGC38204.1 - 4.2e-14 52.6 0.0 1.2e-13 51.2 0.0 1.9 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGC38204.1 - 0.02 14.7 0.0 3 7.8 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like Pheromone PF08015.11 EGC38204.1 - 1.6 9.8 7.4 0.33 12.0 0.6 3.0 3 0 0 3 3 3 0 Fungal mating-type pheromone Ribosomal_L28 PF00830.19 EGC38205.1 - 9.2e-19 67.4 0.1 1.6e-18 66.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal L28 family Band_7_1 PF13421.6 EGC38205.1 - 0.01 15.6 0.0 0.011 15.5 0.0 1.0 1 0 0 1 1 1 0 SPFH domain-Band 7 family ABC1 PF03109.16 EGC38206.1 - 6e-33 113.5 0.0 1.4e-32 112.4 0.0 1.7 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.25 EGC38206.1 - 0.13 11.6 0.1 0.13 11.6 0.1 1.7 2 0 0 2 2 2 0 Protein kinase domain Ricin_B_lectin PF00652.22 EGC38207.1 - 1e-07 32.2 1.6 2.3e-07 31.1 1.6 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.6 EGC38207.1 - 0.02 15.6 11.0 0.029 15.1 8.0 2.7 2 1 1 3 3 3 0 Ricin-type beta-trefoil lectin domain-like MG2 PF01835.19 EGC38207.1 - 0.13 12.7 0.0 0.52 10.8 0.0 2.0 2 0 0 2 2 2 0 MG2 domain FeoB_associated PF12669.7 EGC38209.1 - 0.17 12.3 1.4 0.36 11.3 1.4 1.5 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein MinE PF03776.14 EGC38210.1 - 0.053 13.5 0.5 0.053 13.5 0.5 2.3 2 0 0 2 2 2 0 Septum formation topological specificity factor MinE MCRS_N PF13325.6 EGC38211.1 - 4.2e-18 66.1 3.1 4.2e-18 66.1 3.1 3.5 3 1 1 4 4 4 1 N-terminal region of micro-spherule protein FHA PF00498.26 EGC38211.1 - 2.3e-08 34.2 0.1 1.6e-07 31.5 0.1 2.5 2 0 0 2 2 2 1 FHA domain MIF4G PF02854.19 EGC38212.1 - 2.4e-40 138.4 7.8 2.4e-40 138.4 7.8 2.8 3 0 0 3 3 3 1 MIF4G domain Sulfatase_C PF14707.6 EGC38212.1 - 0.072 13.8 0.4 1 10.1 0.2 2.8 2 0 0 2 2 2 0 C-terminal region of aryl-sulfatase Macoilin PF09726.9 EGC38212.1 - 7.4 5.0 14.9 16 3.9 14.9 1.5 1 0 0 1 1 1 0 Macoilin family Peptidase_C39_2 PF13529.6 EGC38213.1 - 2.5e-09 37.8 0.2 4.4e-09 37.0 0.2 1.4 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGC38213.1 - 0.0086 16.1 0.0 0.0096 15.9 0.0 1.2 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Guanylate_cyc_2 PF09778.9 EGC38213.1 - 0.11 11.9 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Guanylylate cyclase ATP11 PF06644.11 EGC38214.1 - 3.3e-35 122.2 0.1 4.4e-35 121.8 0.1 1.2 1 0 0 1 1 1 1 ATP11 protein DUF3498 PF12004.8 EGC38215.1 - 0.067 12.4 0.4 0.086 12.0 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Glyco_hydro_16 PF00722.21 EGC38216.1 - 9.7e-29 100.1 0.5 1.6e-28 99.4 0.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.15 EGC38216.1 - 5.3e-21 74.6 5.0 1.4e-14 53.4 0.3 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WD40 PF00400.32 EGC38217.1 - 3.4e-48 160.6 24.1 2.9e-08 34.2 0.1 8.5 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38217.1 - 1.1e-22 80.2 1.2 4.8e-05 23.6 0.0 6.2 2 2 3 5 5 5 4 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC38217.1 - 2.3e-09 37.4 6.2 0.0053 16.7 0.1 4.7 2 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A LisH PF08513.11 EGC38217.1 - 2.9e-08 33.4 0.8 6.1e-08 32.4 0.8 1.6 1 0 0 1 1 1 1 LisH Atrophin-1 PF03154.15 EGC38217.1 - 5e-06 25.1 9.5 6.7e-06 24.7 9.5 1.1 1 0 0 1 1 1 1 Atrophin-1 family WD40_like PF17005.5 EGC38217.1 - 1.5e-05 24.5 0.0 0.072 12.4 0.0 3.4 3 0 0 3 3 3 2 WD40-like domain SpoIIP PF07454.11 EGC38217.1 - 0.0088 15.5 7.0 0.02 14.4 7.0 1.6 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DUF3915 PF13054.6 EGC38217.1 - 0.038 14.0 8.9 0.12 12.3 8.9 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3915) DDHD PF02862.17 EGC38217.1 - 0.1 12.8 2.0 0.14 12.3 2.0 1.3 1 0 0 1 1 1 0 DDHD domain MAJIN PF15077.6 EGC38217.1 - 0.35 10.6 9.1 0.54 10.0 9.1 1.2 1 0 0 1 1 1 0 Membrane-anchored junction protein CDC45 PF02724.14 EGC38217.1 - 0.36 9.1 8.3 0.46 8.7 8.3 1.1 1 0 0 1 1 1 0 CDC45-like protein PPL5 PF18168.1 EGC38217.1 - 0.77 9.0 6.9 1.2 8.4 6.9 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Connexin PF00029.19 EGC38217.1 - 1.9 8.2 6.4 3.7 7.3 6.4 1.5 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC38217.1 - 1.9 7.2 8.2 2.6 6.7 8.2 1.1 1 0 0 1 1 1 0 Presenilin FGF-BP1 PF06473.12 EGC38217.1 - 2.1 8.1 15.2 3.3 7.5 15.2 1.2 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) Med19 PF10278.9 EGC38217.1 - 7.4 6.5 18.4 18 5.2 18.4 1.6 1 0 0 1 1 1 0 Mediator of RNA pol II transcription subunit 19 RR_TM4-6 PF06459.12 EGC38217.1 - 8.6 6.1 16.6 13 5.5 16.6 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Pox_Ag35 PF03286.14 EGC38217.1 - 8.6 6.1 20.7 14 5.4 20.7 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Pkinase PF00069.25 EGC38218.1 - 4.4e-78 262.3 0.0 5.7e-78 261.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38218.1 - 2.1e-37 128.8 0.0 2.7e-37 128.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.26 EGC38218.1 - 1.9e-10 41.0 0.1 3.7e-10 40.0 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kdo PF06293.14 EGC38218.1 - 5.3e-08 32.5 0.0 8.1e-08 31.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC38218.1 - 5.2e-07 29.3 0.0 1.3e-06 28.0 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Haspin_kinase PF12330.8 EGC38218.1 - 0.00034 19.7 0.3 0.0005 19.1 0.3 1.2 1 0 0 1 1 1 1 Haspin like kinase domain Pkinase_fungal PF17667.1 EGC38218.1 - 0.0007 18.5 0.0 0.0014 17.5 0.0 1.4 2 0 0 2 2 2 1 Fungal protein kinase Yop-YscD_cpl PF16697.5 EGC38218.1 - 0.017 15.4 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Inner membrane component of T3SS, cytoplasmic domain GbpC PF08363.10 EGC38218.1 - 0.02 14.4 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 Glucan-binding protein C EcKinase PF02958.20 EGC38218.1 - 0.074 12.3 0.0 0.14 11.4 0.0 1.5 1 1 0 1 1 1 0 Ecdysteroid kinase RIO1 PF01163.22 EGC38218.1 - 0.084 12.5 0.2 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 RIO1 family APH PF01636.23 EGC38218.1 - 0.5 10.3 1.1 1.6 8.6 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family adh_short PF00106.25 EGC38219.1 - 9.5e-47 159.0 0.0 1.7e-46 158.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC38219.1 - 1.8e-31 109.5 0.0 2.3e-31 109.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC38219.1 - 5.1e-09 36.3 0.0 9.7e-09 35.4 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC38219.1 - 3.7e-06 26.5 0.0 3.4e-05 23.4 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.6 EGC38219.1 - 1.9e-05 24.6 0.0 3.3e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding RmlD_sub_bind PF04321.17 EGC38219.1 - 0.00054 19.1 0.0 0.00079 18.6 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.21 EGC38219.1 - 0.0039 16.7 0.0 0.0058 16.1 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.15 EGC38219.1 - 0.018 14.2 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Gamma_PGA_hydro PF05908.11 EGC38219.1 - 0.099 12.0 0.5 6.7 6.1 0.0 2.3 2 0 0 2 2 2 0 Poly-gamma-glutamate hydrolase Ribosomal_L9_N PF01281.19 EGC38219.1 - 0.11 12.1 0.0 15 5.3 0.0 2.5 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain zf-TRAF PF02176.18 EGC38220.1 - 2.8e-14 53.5 32.2 2.8e-11 43.9 6.1 3.5 2 1 2 4 4 4 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC38220.1 - 1.6e-06 28.5 14.8 0.0027 18.1 5.0 2.8 1 1 1 2 2 2 2 TRAF-like zinc-finger Sina PF03145.16 EGC38220.1 - 0.0019 18.2 22.0 0.0052 16.7 5.1 3.4 1 1 1 2 2 2 1 Seven in absentia protein family Prefoldin_2 PF01920.20 EGC38220.1 - 0.047 13.6 0.4 0.24 11.4 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit TRAF6_Z2 PF18048.1 EGC38220.1 - 0.45 10.6 0.0 0.45 10.6 0.0 3.8 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-TRAF PF02176.18 EGC38221.1 - 1.5e-14 54.4 33.9 5.9e-11 42.9 6.7 4.9 3 1 2 5 5 5 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC38221.1 - 0.0039 17.6 32.6 0.0063 17.0 7.3 3.9 1 1 2 3 3 3 2 TRAF-like zinc-finger Sina PF03145.16 EGC38221.1 - 0.0076 16.2 5.2 0.0076 16.2 5.2 3.5 1 1 1 2 2 2 1 Seven in absentia protein family Prefoldin_2 PF01920.20 EGC38221.1 - 0.018 15.0 2.1 0.15 12.0 0.1 2.5 2 0 0 2 2 2 0 Prefoldin subunit TRAF6_Z2 PF18048.1 EGC38221.1 - 0.55 10.4 0.0 0.55 10.4 0.0 4.0 3 1 0 3 3 3 0 TNF receptor-associated factor 6 zinc finger 2 zf-C4 PF00105.18 EGC38221.1 - 7.9 7.0 26.1 1.9 9.0 8.3 3.9 2 1 1 3 3 3 0 Zinc finger, C4 type (two domains) zf-TRAF PF02176.18 EGC38222.1 - 9.5e-10 39.0 45.6 7.5e-09 36.2 8.2 4.7 1 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC38222.1 - 0.0046 16.8 14.1 0.0046 16.8 14.1 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC38222.1 - 0.02 14.8 6.7 0.02 14.8 6.7 4.7 5 1 0 5 5 5 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC38222.1 - 0.026 14.4 13.1 0.026 14.4 13.1 3.4 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) DUF4839 PF16127.5 EGC38222.1 - 0.036 14.2 0.0 0.11 12.6 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4839) Med8 PF10232.9 EGC38222.1 - 0.13 11.8 0.2 0.21 11.1 0.2 1.2 1 0 0 1 1 1 0 Mediator of RNA polymerase II transcription complex subunit 8 zf-TRAF_2 PF15965.5 EGC38222.1 - 2.7 8.5 40.1 1.7 9.1 8.9 3.9 1 1 3 4 4 4 0 TRAF-like zinc-finger Cyclin_N PF00134.23 EGC38223.1 - 3e-09 36.7 0.0 6e-06 26.0 0.0 2.3 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC38223.1 - 0.00079 19.5 0.1 0.0017 18.4 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain RdRP PF05183.12 EGC38224.1 - 3.7e-125 418.8 1.7 2.4e-124 416.2 0.0 2.4 3 0 0 3 3 3 1 RNA dependent RNA polymerase ResIII PF04851.15 EGC38224.1 - 8e-17 61.8 0.1 8e-17 61.8 0.1 4.6 5 1 0 5 5 5 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGC38224.1 - 9.6e-17 61.3 9.8 2.9e-16 59.8 0.3 4.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DEAD PF00270.29 EGC38224.1 - 3e-16 59.7 0.8 9.6e-16 58.0 0.1 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SWI2_SNF2 PF18766.1 EGC38224.1 - 0.012 15.3 1.1 0.77 9.4 0.0 2.5 2 0 0 2 2 2 0 SWI2/SNF2 ATPase KH_1 PF00013.29 EGC38224.1 - 0.086 12.7 1.8 0.18 11.7 0.3 2.5 2 0 0 2 2 2 0 KH domain DUF2924 PF11149.8 EGC38224.1 - 0.11 12.9 0.1 0.3 11.5 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) Spore_III_AB PF09548.10 EGC38224.1 - 2.9 8.0 7.5 2 8.5 1.1 2.8 2 0 0 2 2 2 0 Stage III sporulation protein AB (spore_III_AB) EGF_2 PF07974.13 EGC38225.1 - 0.00066 20.0 11.1 0.0011 19.3 11.1 1.3 1 0 0 1 1 1 1 EGF-like domain EGF_Tenascin PF18720.1 EGC38225.1 - 0.0011 19.0 3.9 0.0019 18.2 3.9 1.4 1 0 0 1 1 1 1 Tenascin EGF domain Complex1_LYR PF05347.15 EGC38226.1 - 4.5e-12 45.8 0.8 3.9e-11 42.8 1.0 2.1 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_2 PF13233.6 EGC38226.1 - 3.1e-05 24.7 0.1 4.4e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like ASH PF15780.5 EGC38227.1 - 1e-07 32.1 5.3 0.0018 18.5 0.0 5.0 3 1 1 4 4 4 2 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin CCDC53 PF10152.9 EGC38227.1 - 0.0083 16.6 7.5 0.0083 16.6 7.5 5.3 4 1 0 4 4 4 1 Subunit CCDC53 of WASH complex NAC PF01849.18 EGC38229.1 - 3.9e-14 52.4 0.3 9.7e-14 51.1 0.1 1.7 2 0 0 2 2 2 1 NAC domain MMR_HSR1 PF01926.23 EGC38230.1 - 2.6e-06 27.5 0.1 2.6e-06 27.5 0.1 4.3 4 2 0 4 4 4 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC38230.1 - 5.1e-06 26.5 0.1 5.1e-06 26.5 0.1 3.4 4 0 0 4 4 4 1 RsgA GTPase Roc PF08477.13 EGC38230.1 - 0.011 15.9 4.7 1.9 8.7 0.1 3.2 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase AAA_33 PF13671.6 EGC38230.1 - 0.043 14.0 0.3 0.3 11.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_14 PF13173.6 EGC38230.1 - 0.044 13.8 0.1 0.044 13.8 0.1 4.0 4 1 0 4 4 4 0 AAA domain ABC_tran PF00005.27 EGC38230.1 - 0.069 13.7 0.0 0.069 13.7 0.0 3.8 3 1 0 3 3 3 0 ABC transporter AAA_18 PF13238.6 EGC38230.1 - 0.53 10.8 0.0 0.53 10.8 0.0 4.9 3 2 1 5 5 5 0 AAA domain Tubulin_3 PF14881.6 EGC38230.1 - 0.81 9.3 0.0 0.81 9.3 0.0 3.5 5 0 0 5 5 5 0 Tubulin domain ATP_bind_1 PF03029.17 EGC38230.1 - 2.2 8.0 9.8 9.8 5.9 2.1 4.3 2 2 1 3 3 3 0 Conserved hypothetical ATP binding protein DUF572 PF04502.13 EGC38231.1 - 2.6e-64 217.9 16.6 3.1e-64 217.7 16.6 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) C1_4 PF07975.12 EGC38231.1 - 0.051 13.8 0.4 0.15 12.3 0.4 1.9 1 0 0 1 1 1 0 TFIIH C1-like domain NAPRTase_N PF17767.1 EGC38231.1 - 0.14 12.6 2.1 0.22 11.9 1.6 1.7 2 0 0 2 2 2 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain PUL PF08324.11 EGC38232.1 - 1.1e-44 152.8 3.0 1.8e-44 152.1 3.0 1.2 1 0 0 1 1 1 1 PUL domain Peptidase_C97 PF05903.14 EGC38232.1 - 2.8e-40 137.6 0.0 5.6e-40 136.6 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.13 EGC38232.1 - 0.0077 16.5 2.0 0.056 13.8 0.8 2.4 2 0 0 2 2 2 1 Lecithin retinol acyltransferase MHCassoc_trimer PF08831.10 EGC38232.1 - 0.13 12.3 0.6 0.38 10.8 0.6 1.7 1 0 0 1 1 1 0 Class II MHC-associated invariant chain trimerisation domain ABC2_membrane PF01061.24 EGC38233.1 - 2.9e-80 268.6 65.0 3.8e-46 157.2 21.8 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC38233.1 - 5.1e-45 153.4 0.7 4e-22 79.2 0.1 2.5 2 0 0 2 2 2 2 ABC transporter RsgA_GTPase PF03193.16 EGC38233.1 - 8.3e-08 32.3 1.2 0.00053 19.9 0.3 2.6 2 0 0 2 2 2 2 RsgA GTPase AAA_21 PF13304.6 EGC38233.1 - 8.6e-08 32.3 7.2 0.32 10.7 0.0 5.2 4 1 1 6 6 6 3 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC38233.1 - 9.3e-07 29.4 0.0 0.034 14.5 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain Rad17 PF03215.15 EGC38233.1 - 6.7e-06 26.2 1.2 0.28 11.1 0.0 3.7 4 0 0 4 4 4 2 Rad17 P-loop domain SMC_N PF02463.19 EGC38233.1 - 1.2e-05 24.8 5.6 0.012 15.0 1.4 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_18 PF13238.6 EGC38233.1 - 1.2e-05 25.8 4.7 0.033 14.7 0.0 3.4 3 1 0 3 3 3 2 AAA domain AAA_29 PF13555.6 EGC38233.1 - 1.3e-05 24.8 0.6 0.0047 16.6 0.1 2.7 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC38233.1 - 2e-05 24.9 0.3 0.39 11.0 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGC38233.1 - 2.4e-05 24.0 0.0 0.14 11.7 0.0 2.5 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGC38233.1 - 0.0003 21.2 3.7 0.088 13.2 0.0 3.5 3 0 0 3 3 3 1 RNA helicase Zeta_toxin PF06414.12 EGC38233.1 - 0.00063 19.1 0.1 0.087 12.1 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin AAA PF00004.29 EGC38233.1 - 0.0012 19.2 3.8 0.019 15.4 0.3 3.4 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) PDR_CDR PF06422.12 EGC38233.1 - 0.0014 18.4 1.7 0.15 12.0 0.3 2.9 2 0 0 2 2 2 1 CDR ABC transporter AAA_5 PF07728.14 EGC38233.1 - 0.0019 18.2 1.0 0.33 10.9 0.0 2.9 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.6 EGC38233.1 - 0.0021 18.2 1.3 2.6 8.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain AAA_28 PF13521.6 EGC38233.1 - 0.0021 18.3 0.2 2.2 8.5 0.0 2.3 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC38233.1 - 0.0022 18.0 0.6 2 8.5 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase NACHT PF05729.12 EGC38233.1 - 0.0069 16.3 0.5 2.2 8.2 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_30 PF13604.6 EGC38233.1 - 0.011 15.4 0.1 5.4 6.7 0.2 2.4 2 0 0 2 2 2 0 AAA domain NTPase_1 PF03266.15 EGC38233.1 - 0.016 15.1 0.8 18 5.2 0.0 3.4 3 0 0 3 3 3 0 NTPase Roc PF08477.13 EGC38233.1 - 0.019 15.2 0.1 8.4 6.6 0.0 2.7 2 0 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase CCSMST1 PF15013.6 EGC38233.1 - 0.038 14.2 0.4 4.2 7.6 0.0 2.7 2 0 0 2 2 2 0 CCSMST1 family PduV-EutP PF10662.9 EGC38233.1 - 0.058 13.1 2.7 2.4 7.9 0.0 3.1 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGC38233.1 - 0.062 12.8 0.5 2.3 7.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing dynein motor region RuvB_N PF05496.12 EGC38233.1 - 0.091 12.5 0.4 1.4 8.6 0.1 2.3 2 0 0 2 2 2 0 Holliday junction DNA helicase RuvB P-loop domain PRK PF00485.18 EGC38233.1 - 0.1 12.3 0.0 7.7 6.2 0.0 2.5 2 0 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family OAD_gamma PF04277.13 EGC38233.1 - 0.13 12.9 0.0 0.13 12.9 0.0 2.6 2 0 0 2 2 1 0 Oxaloacetate decarboxylase, gamma chain DUF815 PF05673.13 EGC38233.1 - 0.15 11.2 1.1 0.72 9.0 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_23 PF13476.6 EGC38233.1 - 0.17 12.4 19.2 0.2 12.1 0.6 3.7 2 1 0 3 3 2 0 AAA domain IstB_IS21 PF01695.17 EGC38233.1 - 0.18 11.5 0.0 7.6 6.2 0.0 2.6 2 0 0 2 2 2 0 IstB-like ATP binding protein TsaE PF02367.17 EGC38233.1 - 0.26 11.3 1.4 14 5.7 0.1 2.4 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_11 PF13086.6 EGC38233.1 - 0.32 10.7 2.6 0.67 9.7 0.0 2.2 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGC38233.1 - 2.7 8.0 10.2 4.2 7.4 0.1 3.3 3 0 0 3 3 3 0 Helicase HerA, central domain cobW PF02492.19 EGC38233.1 - 3 7.4 7.5 9.1 5.8 0.2 3.1 3 0 0 3 3 3 0 CobW/HypB/UreG, nucleotide-binding domain TPR_12 PF13424.6 EGC38235.1 - 3.3e-12 46.5 3.1 0.00012 22.3 0.1 3.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC38235.1 - 1.2e-06 28.2 12.3 0.2 11.8 0.3 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGC38235.1 - 3.7e-05 23.3 13.0 0.056 13.3 0.1 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38235.1 - 0.0019 18.3 10.2 1.2 9.6 0.0 5.0 5 1 0 5 5 5 2 Tetratricopeptide repeat TPR_10 PF13374.6 EGC38235.1 - 0.0045 16.8 5.4 0.45 10.4 0.3 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC38235.1 - 0.043 14.2 1.6 51 4.6 0.1 4.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC38235.1 - 0.1 13.3 1.6 22 5.8 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC38235.1 - 0.14 12.3 2.5 31 4.9 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.14 EGC38235.1 - 0.22 12.2 0.0 10 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat RNA_polI_A14 PF08203.11 EGC38235.1 - 3.9 8.3 9.0 4.3 8.1 1.7 2.8 2 0 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Ammonium_transp PF00909.21 EGC38236.1 - 8.3e-54 182.8 18.6 1.3e-53 182.1 18.6 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4611 PF15387.6 EGC38236.1 - 0.083 13.1 1.0 0.15 12.3 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Kinocilin PF15033.6 EGC38236.1 - 0.47 10.1 2.1 0.79 9.4 0.3 2.3 2 0 0 2 2 2 0 Kinocilin protein Allantoicase PF03561.15 EGC38237.1 - 1.1e-95 317.3 0.0 5.5e-49 165.8 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat DUF1084 PF06454.11 EGC38238.1 - 2.5e-08 33.7 23.8 8.8e-06 25.3 1.8 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1084) MAP65_ASE1 PF03999.12 EGC38239.1 - 1.2e-53 182.7 44.3 1.9e-53 182.1 44.3 1.3 1 0 0 1 1 1 1 Microtubule associated protein (MAP65/ASE1 family) Retrotrans_gag PF03732.17 EGC38239.1 - 0.073 13.4 0.3 5.7 7.3 0.0 3.2 2 0 0 2 2 2 0 Retrotransposon gag protein MCLC PF05934.11 EGC38239.1 - 0.075 11.8 0.0 0.2 10.4 0.0 1.6 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) DUF5618 PF18498.1 EGC38239.1 - 0.46 10.7 7.7 0.1 12.8 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF5618) Erf4 PF10256.9 EGC38240.1 - 5.1 7.2 14.3 0.11 12.6 2.6 3.2 1 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.9 EGC38241.1 - 0.0023 18.0 8.1 0.0024 18.0 2.0 3.0 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF202 PF02656.15 EGC38241.1 - 0.0025 18.2 1.9 0.004 17.6 1.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF202) MLANA PF14991.6 EGC38241.1 - 0.0053 17.0 0.2 0.021 15.1 0.0 2.1 2 0 0 2 2 2 1 Protein melan-A CD47 PF04549.14 EGC38241.1 - 0.012 15.8 0.7 0.019 15.1 0.7 1.3 1 0 0 1 1 1 0 CD47 transmembrane region ETRAMP PF09716.10 EGC38241.1 - 4.1 7.5 7.5 21 5.3 0.0 3.7 4 0 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) Peptidase_M20 PF01546.28 EGC38242.1 - 6.7e-32 110.9 0.0 9.5e-32 110.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC38242.1 - 4e-11 42.8 0.0 6.4e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGC38242.1 - 2.5e-07 30.6 0.0 5.3e-06 26.3 0.0 2.3 2 0 0 2 2 2 1 Peptidase family M28 Myb_DNA-binding PF00249.31 EGC38243.1 - 3.1e-15 56.1 0.0 1.4e-07 31.6 0.0 2.5 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC38243.1 - 1.1e-07 32.0 13.3 0.00022 21.4 0.4 4.2 4 0 0 4 4 4 2 Myb-like DNA-binding domain Tn7_Tnp_TnsA_C PF08721.11 EGC38244.1 - 0.04 14.5 0.1 0.068 13.8 0.1 1.3 1 0 0 1 1 1 0 TnsA endonuclease C terminal Ceramidase PF05875.12 EGC38245.1 - 5.2e-55 186.7 9.4 6.7e-55 186.3 9.4 1.1 1 0 0 1 1 1 1 Ceramidase DUF3449 PF11931.8 EGC38246.1 - 1.1e-63 214.4 3.4 1.1e-63 214.4 3.4 3.5 3 1 1 4 4 4 1 Domain of unknown function (DUF3449) SF3A3 PF16837.5 EGC38246.1 - 2.7e-22 79.0 10.2 2.7e-22 79.0 10.2 3.2 3 0 0 3 3 3 1 Pre-mRNA-splicing factor SF3A3, of SF3a complex, Prp9 SF3a60_bindingd PF12108.8 EGC38246.1 - 1.3e-11 44.1 4.6 4.7e-11 42.4 0.5 2.9 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.7 EGC38246.1 - 4.2e-11 42.9 7.3 3e-08 33.8 1.8 2.9 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC38246.1 - 5.3e-09 36.1 0.7 5.3e-09 36.1 0.7 3.3 2 1 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGC38246.1 - 0.00087 19.6 5.1 0.19 12.0 0.2 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGC38246.1 - 0.045 14.6 5.5 2.8 9.0 0.1 3.2 3 0 0 3 3 3 0 C2H2-type zinc finger Desulfoferrod_N PF06397.12 EGC38246.1 - 0.19 11.4 0.6 0.35 10.5 0.6 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain zf-C2H2_6 PF13912.6 EGC38246.1 - 2.6 8.2 8.3 0.65 10.1 2.0 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_3rep PF18868.1 EGC38246.1 - 9.9 6.9 8.4 8.5 7.1 0.3 3.1 2 1 1 3 3 3 0 Zinc finger C2H2-type, 3 repeats TatD_DNase PF01026.21 EGC38247.1 - 3.4e-60 203.6 0.0 4.1e-60 203.3 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase Menin PF05053.13 EGC38247.1 - 0.27 9.6 3.9 0.37 9.1 3.9 1.1 1 0 0 1 1 1 0 Menin NST1 PF13945.6 EGC38247.1 - 0.32 11.1 5.4 0.57 10.3 5.4 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator zf-C3HC4_3 PF13920.6 EGC38248.1 - 3.3e-06 26.9 12.9 3.3e-06 26.9 12.9 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38248.1 - 3.8e-06 26.7 16.3 3.8e-06 26.7 16.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38248.1 - 1.7e-05 24.6 13.7 1.7e-05 24.6 13.7 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38248.1 - 4.4e-05 23.7 14.8 4.4e-05 23.7 14.8 2.6 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.6 EGC38248.1 - 6.5e-05 22.7 6.8 6.5e-05 22.7 6.8 2.0 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.6 EGC38248.1 - 0.00093 19.3 15.9 0.00093 19.3 15.9 2.9 2 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC38248.1 - 0.016 15.1 15.7 0.016 15.1 15.7 2.5 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC38248.1 - 2.6 8.1 19.8 0.062 13.3 12.7 2.1 2 0 0 2 2 2 0 RING-type zinc-finger Mvb12 PF09452.10 EGC38249.1 - 0.025 15.0 1.8 0.081 13.4 1.8 1.9 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Papilloma_E5 PF03025.14 EGC38249.1 - 0.1 12.8 12.1 0.17 12.0 12.1 1.3 1 0 0 1 1 1 0 Papillomavirus E5 Cpta_toxin PF07254.12 EGC38249.1 - 0.27 11.2 2.2 0.56 10.2 2.2 1.5 1 0 0 1 1 1 0 Membrane-bound toxin component of toxin-antitoxin system Bunya_G2 PF03563.13 EGC38249.1 - 3 7.0 8.5 5.4 6.2 8.5 1.4 1 0 0 1 1 1 0 Bunyavirus glycoprotein G2 2TM PF13239.6 EGC38249.1 - 3.2 8.1 8.1 6.1 7.2 6.9 2.0 2 0 0 2 2 2 0 2TM domain Halogen_Hydrol PF10112.9 EGC38249.1 - 6.7 6.7 14.5 1.1 9.2 2.7 2.2 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein Mem_trans PF03547.18 EGC38250.1 - 0.0019 16.7 4.2 0.0027 16.2 4.2 1.1 1 0 0 1 1 1 1 Membrane transport protein Shisa PF13908.6 EGC38250.1 - 0.41 10.9 3.0 0.96 9.7 3.0 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Glucos_trans_II PF14264.6 EGC38251.1 - 0.00029 20.3 0.4 0.00048 19.6 0.4 1.3 1 0 0 1 1 1 1 Glucosyl transferase GtrII CAAD PF14159.6 EGC38251.1 - 0.0012 18.6 0.3 0.002 17.9 0.3 1.4 1 0 0 1 1 1 1 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase Erf4 PF10256.9 EGC38251.1 - 0.0012 18.9 0.3 0.0078 16.3 0.3 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Polysacc_synt PF01943.17 EGC38251.1 - 0.0052 16.2 0.1 0.0078 15.6 0.1 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein STT3 PF02516.14 EGC38251.1 - 0.011 14.7 0.3 0.014 14.4 0.3 1.2 1 0 0 1 1 1 0 Oligosaccharyl transferase STT3 subunit DUF5455 PF17537.2 EGC38251.1 - 0.022 15.1 0.6 0.038 14.4 0.6 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5455) Tetraspanin PF00335.20 EGC38251.1 - 0.036 13.8 0.0 0.036 13.8 0.0 1.6 2 0 0 2 2 2 0 Tetraspanin family DUF4131 PF13567.6 EGC38251.1 - 0.06 13.0 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Wzy_C PF04932.15 EGC38251.1 - 0.079 12.6 0.4 0.13 11.9 0.4 1.4 1 0 0 1 1 1 0 O-Antigen ligase Phage_holin_3_6 PF07332.11 EGC38251.1 - 0.16 12.0 0.0 0.24 11.5 0.0 1.2 1 0 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III HlyIII PF03006.20 EGC38251.1 - 0.16 11.6 3.6 0.26 11.0 3.4 1.4 1 1 0 1 1 1 0 Haemolysin-III related DUF2614 PF11023.8 EGC38251.1 - 0.45 10.6 4.4 0.77 9.9 4.4 1.3 1 0 0 1 1 1 0 Zinc-ribbon containing domain Sigma_reg_N PF13800.6 EGC38251.1 - 1.9 8.9 6.5 12 6.2 0.2 2.8 1 1 1 2 2 2 0 Sigma factor regulator N-terminal DUF2207 PF09972.9 EGC38251.1 - 1.9 7.1 8.3 3.6 6.3 8.3 1.5 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Insulin_TMD PF17870.1 EGC38251.1 - 2.2 8.4 7.7 26 5.0 0.1 2.4 2 0 0 2 2 2 0 Insulin receptor trans-membrane segment Aldedh PF00171.22 EGC38252.1 - 4.6e-132 440.8 0.0 5.4e-132 440.6 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.25 EGC38253.1 - 8.6e-39 133.5 1.5 4e-32 111.6 0.4 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38253.1 - 1.1e-27 97.0 2.8 3.9e-27 95.2 2.8 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.25 EGC38253.1 - 7.4e-05 23.0 0.0 0.00014 22.1 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Pkinase_fungal PF17667.1 EGC38253.1 - 0.00041 19.2 2.3 0.00078 18.3 2.3 1.5 1 0 0 1 1 1 1 Fungal protein kinase Acetyltransf_7 PF13508.7 EGC38253.1 - 0.0012 19.3 0.0 0.003 18.0 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC38253.1 - 0.051 13.5 0.0 0.12 12.4 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_12 PF08242.12 EGC38253.1 - 0.053 14.3 0.9 0.21 12.4 0.9 2.0 1 0 0 1 1 1 0 Methyltransferase domain Coiled PF05710.12 EGC38255.1 - 0.14 13.0 3.0 0.17 12.7 3.0 1.1 1 0 0 1 1 1 0 Coiled coil RhoGAP PF00620.27 EGC38256.1 - 3.4e-24 85.4 0.1 2.1e-23 82.9 0.0 2.4 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.23 EGC38256.1 - 4.2e-13 49.4 1.3 4.2e-13 49.4 1.3 3.5 5 0 0 5 5 5 1 Fes/CIP4, and EFC/F-BAR homology domain RP-C_C PF11800.8 EGC38256.1 - 7.7 6.6 8.3 1 9.4 1.1 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Strep_SA_rep PF06696.11 EGC38257.1 - 0.76 9.8 3.6 4.1 7.5 0.7 2.8 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DNTTIP1_dimer PF18192.1 EGC38257.1 - 2.2 8.7 4.7 1 9.8 0.3 2.5 2 1 1 3 3 3 0 DNTTIP1 dimerisation domain WD40 PF00400.32 EGC38258.1 - 1.3e-41 139.8 21.8 2.7e-09 37.5 0.1 8.2 8 0 0 8 8 8 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38258.1 - 5.9e-14 52.1 1.6 6e-08 32.9 0.1 4.4 2 1 1 4 4 4 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC38258.1 - 1.9e-07 30.7 2.7 0.011 15.1 0.0 3.4 2 2 2 4 4 4 4 WD40-like domain eIF2A PF08662.11 EGC38258.1 - 4.7e-07 29.9 3.6 0.013 15.3 0.0 3.5 1 1 3 4 4 4 3 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.11 EGC38258.1 - 0.00016 20.5 0.3 0.059 12.1 0.1 3.3 3 0 0 3 3 3 1 Nup133 N terminal like Ge1_WD40 PF16529.5 EGC38258.1 - 0.00093 18.2 0.1 0.32 9.9 0.0 2.5 3 0 0 3 3 3 2 WD40 region of Ge1, enhancer of mRNA-decapping protein Nup160 PF11715.8 EGC38258.1 - 0.02 13.5 1.8 0.46 9.1 0.8 2.6 2 1 1 3 3 3 0 Nucleoporin Nup120/160 OTU PF02338.19 EGC38259.1 - 7.2e-12 45.9 0.0 7.2e-12 45.9 0.0 3.2 2 1 0 2 2 2 1 OTU-like cysteine protease Presenilin PF01080.17 EGC38259.1 - 0.18 10.5 8.4 0.21 10.3 8.4 1.1 1 0 0 1 1 1 0 Presenilin TFIIA PF03153.13 EGC38259.1 - 0.2 11.6 38.1 0.27 11.2 38.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Vac7 PF12751.7 EGC38259.1 - 2.2 7.6 7.9 3 7.2 7.9 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 Band_3_cyto PF07565.13 EGC38259.1 - 5.2 6.8 15.4 8.1 6.2 15.4 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Sin_N PF04801.13 EGC38259.1 - 6 6.0 32.8 7.8 5.6 32.8 1.1 1 0 0 1 1 1 0 Sin-like protein conserved region UAA PF08449.11 EGC38260.1 - 1.2e-64 218.4 21.4 1.5e-64 218.1 21.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGC38260.1 - 6.7e-08 32.8 20.0 0.0001 22.5 10.7 2.7 3 0 0 3 3 3 2 EamA-like transporter family TPT PF03151.16 EGC38260.1 - 0.0065 15.9 12.7 0.012 15.0 9.1 2.0 1 1 1 2 2 2 1 Triose-phosphate Transporter family FAD_binding_4 PF01565.23 EGC38261.1 - 1.6e-23 82.9 0.0 2.9e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.12 EGC38261.1 - 1.7e-13 50.4 3.8 1.7e-13 50.4 3.8 2.3 2 0 0 2 2 2 1 Berberine and berberine like Solute_trans_a PF03619.16 EGC38262.1 - 1.3e-65 221.6 26.0 1.6e-65 221.3 26.0 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ketoacyl-synt PF00109.26 EGC38263.1 - 2.4e-62 210.8 0.0 3.8e-62 210.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC38263.1 - 2.7e-53 180.8 0.0 6.3e-53 179.6 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC38263.1 - 4.9e-42 144.5 0.0 7.8e-42 143.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38263.1 - 1.3e-36 125.2 0.0 3e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38263.1 - 1.5e-28 99.9 0.0 1.4e-25 90.2 0.0 3.5 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGC38263.1 - 9.2e-21 74.3 0.0 1.5e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38263.1 - 2e-17 63.7 2.3 1.9e-16 60.5 0.3 3.9 5 0 0 5 5 5 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGC38263.1 - 2.6e-07 30.3 0.0 6.1e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGC38263.1 - 2e-05 23.9 0.0 5e-05 22.5 0.0 1.6 1 1 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N_2 PF13602.6 EGC38263.1 - 6.5e-05 24.0 0.0 0.00016 22.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase GDP_Man_Dehyd PF16363.5 EGC38263.1 - 8.5e-05 22.1 1.1 0.067 12.6 0.3 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 EGC38263.1 - 0.00027 20.8 0.0 0.00057 19.7 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38263.1 - 0.0063 15.9 0.0 0.012 15.0 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.26 EGC38264.1 - 2.7e-64 217.2 0.0 4.5e-64 216.4 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38264.1 - 8.7e-40 137.2 0.0 1.4e-39 136.5 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38264.1 - 1.2e-36 125.3 0.0 2.7e-36 124.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38264.1 - 1.2e-27 96.9 0.0 1e-26 93.9 0.0 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC38264.1 - 1.2e-19 70.7 0.0 1.9e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38264.1 - 1.7e-18 67.1 2.5 9.5e-18 64.7 0.3 3.5 4 0 0 4 4 4 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38264.1 - 3.7e-06 28.0 0.0 8.8e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38264.1 - 3e-05 23.9 0.0 6.6e-05 22.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38264.1 - 0.0015 18.0 0.1 0.0028 17.0 0.1 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_4 PF07993.12 EGC38265.1 - 4.9e-54 183.2 0.0 1.2e-53 181.9 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.21 EGC38265.1 - 7.6e-09 35.4 0.0 1.7e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC38265.1 - 1.6e-06 27.4 2.1 2.2e-06 26.9 0.0 2.1 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.17 EGC38265.1 - 1.8e-05 24.0 0.0 0.00013 21.2 0.0 2.0 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGC38265.1 - 0.00031 20.2 0.4 0.0016 17.9 0.3 2.0 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase Lip_prot_lig_C PF10437.9 EGC38265.1 - 0.086 12.8 5.5 2.8 8.0 0.1 3.6 3 0 0 3 3 3 0 Bacterial lipoate protein ligase C-terminus Semialdhyde_dh PF01118.24 EGC38265.1 - 0.18 12.3 0.0 0.34 11.4 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EGC38266.1 - 1e-27 97.2 0.0 1.5e-27 96.6 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGC38266.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase ADH_zinc_N_2 PF13602.6 EGC38266.1 - 0.017 16.2 0.0 0.031 15.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ketoacyl-synt PF00109.26 EGC38267.1 - 2.4e-61 207.5 0.0 4.6e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38267.1 - 1.6e-40 139.6 0.0 2.7e-40 138.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38267.1 - 2.6e-36 124.2 0.0 6.1e-36 123.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.12 EGC38267.1 - 2.5e-32 112.0 0.0 6.9e-32 110.6 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein KR PF08659.10 EGC38267.1 - 8e-29 100.8 0.0 2.8e-26 92.5 0.0 3.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGC38267.1 - 4e-20 72.3 0.0 6.4e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38267.1 - 1.8e-17 63.8 3.7 9.7e-17 61.4 0.3 4.1 5 0 0 5 5 5 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38267.1 - 2.8e-06 28.4 0.0 6.8e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38267.1 - 0.00065 19.6 0.0 0.0014 18.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EGC38267.1 - 0.0019 17.7 0.2 1.9 7.8 0.0 2.4 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EGC38267.1 - 0.0055 16.1 0.0 0.01 15.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Epimerase PF01370.21 EGC38267.1 - 0.13 11.7 0.0 0.56 9.6 0.0 2.1 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.26 EGC38268.1 - 4.4e-60 203.4 0.0 7.2e-60 202.7 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC38268.1 - 1.6e-53 181.5 0.0 4e-53 180.2 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC38268.1 - 7.6e-40 137.3 0.0 1.3e-39 136.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38268.1 - 1.2e-36 125.3 0.0 2.9e-36 124.0 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38268.1 - 3e-28 98.9 0.0 7.2e-26 91.2 0.0 3.1 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGC38268.1 - 1.9e-20 73.3 0.0 3e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38268.1 - 3.4e-17 62.9 3.5 1.3e-16 61.0 0.2 3.9 5 0 0 5 5 4 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGC38268.1 - 8e-08 32.0 0.0 2.4e-07 30.5 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.6 EGC38268.1 - 3.6e-06 28.1 0.0 8.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.17 EGC38268.1 - 1.2e-05 24.6 0.0 3.3e-05 23.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain GDP_Man_Dehyd PF16363.5 EGC38268.1 - 3.5e-05 23.4 1.2 0.022 14.2 0.4 2.8 2 1 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 EGC38268.1 - 0.0002 21.2 0.0 0.00044 20.1 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38268.1 - 0.0063 15.9 0.0 0.013 14.9 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.24 EGC38268.1 - 0.092 13.2 0.0 1.2 9.6 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ketoacyl-synt PF00109.26 EGC38269.1 - 7.9e-60 202.6 0.0 1.3e-59 201.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC38269.1 - 7.3e-54 182.6 0.0 1.6e-53 181.5 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC38269.1 - 3e-38 132.1 0.0 5.1e-38 131.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38269.1 - 2.2e-36 124.4 0.0 5.1e-36 123.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38269.1 - 1.3e-28 100.2 0.0 4.1e-26 92.0 0.0 3.3 3 0 0 3 3 3 1 KR domain PS-DH PF14765.6 EGC38269.1 - 5.1e-21 75.2 0.0 8.2e-21 74.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38269.1 - 2.4e-17 63.4 3.6 6.6e-17 62.0 0.2 3.7 5 0 0 5 5 4 1 Ketoacyl-synthetase C-terminal extension Epimerase PF01370.21 EGC38269.1 - 5.7e-08 32.5 0.0 1.7e-07 31.0 0.0 1.9 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC38269.1 - 1e-05 25.1 0.2 0.0095 15.4 0.0 2.7 2 0 0 2 2 2 2 GDP-mannose 4,6 dehydratase ADH_zinc_N_2 PF13602.6 EGC38269.1 - 2.1e-05 25.6 0.0 5.3e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38269.1 - 6.8e-05 22.7 0.0 0.00016 21.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.17 EGC38269.1 - 0.00082 18.6 0.0 0.0023 17.1 0.0 1.7 1 1 0 1 1 1 1 RmlD substrate binding domain Thiolase_N PF00108.23 EGC38269.1 - 0.0082 15.5 0.0 0.017 14.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain CD24 PF14984.6 EGC38269.1 - 0.06 13.6 0.2 0.29 11.4 0.0 2.3 2 0 0 2 2 1 0 CD24 protein Semialdhyde_dh PF01118.24 EGC38269.1 - 0.1 13.1 0.0 2.4 8.6 0.0 2.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thiolase_N PF00108.23 EGC38270.1 - 9.8e-65 218.5 0.0 1.7e-64 217.7 0.0 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGC38270.1 - 7.7e-45 151.5 0.1 1.3e-44 150.8 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGC38270.1 - 0.0004 20.0 0.4 0.00072 19.2 0.4 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF2802 PF10975.8 EGC38270.1 - 0.002 18.2 0.0 0.32 11.2 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2802) DUF4108 PF13390.6 EGC38271.1 - 0.019 14.9 0.9 0.019 14.9 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4108) HTH_7 PF02796.15 EGC38272.1 - 0.0033 17.5 0.2 0.0089 16.1 0.2 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Methyltransf_31 PF13847.6 EGC38272.1 - 0.16 11.8 3.0 0.14 11.9 0.9 1.9 1 1 0 2 2 2 0 Methyltransferase domain RasGEF PF00617.19 EGC38273.1 - 1.1e-62 211.4 2.8 3.3e-62 209.8 2.8 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.20 EGC38273.1 - 3e-27 94.9 0.3 3e-27 94.9 0.3 4.5 5 0 0 5 5 5 2 RasGEF N-terminal motif adh_short PF00106.25 EGC38274.1 - 2.8e-39 134.6 0.0 4.3e-39 134.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC38274.1 - 2.3e-18 66.6 0.0 3.6e-18 66.0 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC38274.1 - 7.6e-06 25.9 0.0 1.3e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.6 EGC38274.1 - 0.00091 19.2 0.0 0.0016 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC38274.1 - 0.013 14.6 0.1 0.018 14.1 0.1 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.15 EGC38274.1 - 0.031 13.4 0.1 0.044 12.9 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.18 EGC38274.1 - 0.043 14.1 0.0 0.12 12.7 0.0 1.7 2 0 0 2 2 2 0 TrkA-N domain Epimerase PF01370.21 EGC38274.1 - 0.088 12.3 0.0 0.2 11.1 0.0 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family ETRAMP PF09716.10 EGC38275.1 - 4.3 7.5 9.9 2.6 8.2 7.7 1.8 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CRIC_ras_sig PF10534.9 EGC38276.1 - 0.054 13.7 0.1 0.069 13.3 0.1 1.2 1 0 0 1 1 1 0 Connector enhancer of kinase suppressor of ras ABC2_membrane PF01061.24 EGC38277.1 - 1.1e-89 299.4 68.5 4e-47 160.3 23.1 3.2 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC38277.1 - 1.1e-39 136.1 0.0 5.4e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGC38277.1 - 7.2e-26 89.9 14.0 5.5e-21 74.3 0.0 3.8 3 0 0 3 3 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC38277.1 - 8.9e-12 45.5 0.1 2.4e-11 44.1 0.1 1.7 1 0 0 1 1 1 1 ABC-transporter N-terminal ABC2_membrane_3 PF12698.7 EGC38277.1 - 2.2e-10 40.2 56.8 3.6e-07 29.6 17.9 3.7 2 1 0 3 3 3 2 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGC38277.1 - 6.2e-07 29.5 0.2 0.00016 21.7 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase AAA_16 PF13191.6 EGC38277.1 - 1.1e-05 25.9 0.0 0.0029 18.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGC38277.1 - 2.9e-05 23.7 0.4 0.0067 16.1 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC38277.1 - 4.8e-05 23.3 0.0 0.14 11.9 0.0 2.6 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_22 PF13401.6 EGC38277.1 - 5.4e-05 23.5 0.0 0.083 13.2 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.6 EGC38277.1 - 0.0036 16.9 0.8 0.0061 16.2 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC38277.1 - 0.0036 17.8 0.0 0.79 10.3 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.6 EGC38277.1 - 0.0048 17.1 0.0 0.29 11.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain cobW PF02492.19 EGC38277.1 - 0.0083 15.7 0.1 0.11 12.1 0.1 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGC38277.1 - 0.0092 16.1 0.0 6.3 6.9 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Zeta_toxin PF06414.12 EGC38277.1 - 0.011 15.0 0.0 4.3 6.6 0.0 2.6 2 0 0 2 2 2 0 Zeta toxin Rad17 PF03215.15 EGC38277.1 - 0.022 14.7 0.0 2.3 8.1 0.0 2.4 2 0 0 2 2 2 0 Rad17 P-loop domain AAA_30 PF13604.6 EGC38277.1 - 0.029 14.1 0.1 2.1 8.0 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGC38277.1 - 0.047 14.1 0.5 8.5 6.8 0.1 3.6 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Glyco_hydro_36C PF16874.5 EGC38277.1 - 0.048 14.2 0.0 0.34 11.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl hydrolase family 36 C-terminal domain ATP-synt_ab PF00006.25 EGC38277.1 - 0.11 12.2 0.0 6.7 6.3 0.0 2.7 3 0 0 3 3 3 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_24 PF13479.6 EGC38277.1 - 0.16 11.7 0.0 0.49 10.1 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_28 PF13521.6 EGC38277.1 - 0.17 12.1 0.4 0.73 10.1 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.6 EGC38277.1 - 0.19 12.2 0.3 1.2 9.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain JTB PF05439.12 EGC38277.1 - 0.2 11.7 0.8 1.6 8.8 0.1 2.7 2 0 0 2 2 2 0 Jumping translocation breakpoint protein (JTB) IP_trans PF02121.18 EGC38278.1 - 2.6e-98 328.5 1.7 4e-98 327.9 1.7 1.3 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Prenylcys_lyase PF07156.14 EGC38278.1 - 0.021 14.0 0.1 0.038 13.1 0.1 1.4 1 0 0 1 1 1 0 Prenylcysteine lyase Coq4 PF05019.13 EGC38279.1 - 7.3e-87 290.3 0.0 9e-87 290.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ORC5_C PF14630.6 EGC38279.1 - 0.055 13.0 0.0 0.078 12.5 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus PH PF00169.29 EGC38280.1 - 6.3e-31 107.0 13.3 1.3e-14 54.5 0.9 4.4 3 1 0 3 3 3 3 PH domain PH_11 PF15413.6 EGC38280.1 - 1.5e-10 41.5 16.8 0.012 16.0 1.7 5.5 3 2 0 3 3 3 3 Pleckstrin homology domain PH_8 PF15409.6 EGC38280.1 - 0.0003 21.0 7.4 0.029 14.6 0.4 4.5 4 1 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.6 EGC38280.1 - 0.0031 17.8 2.4 0.084 13.3 0.1 3.4 3 0 0 3 3 3 1 Pleckstrin homology domain PH_13 PF16652.5 EGC38280.1 - 0.013 15.3 1.7 4.2 7.2 0.1 3.3 2 1 1 3 3 3 0 Pleckstrin homology domain PH_3 PF14593.6 EGC38280.1 - 0.016 15.3 9.0 0.029 14.5 0.4 4.1 4 1 0 4 4 4 0 PH domain FGGY_N PF00370.21 EGC38282.1 - 9.4e-46 156.3 0.1 1.1e-44 152.9 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.16 EGC38282.1 - 5.8e-38 130.6 0.2 2.6e-37 128.5 0.1 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain YIF1 PF03878.15 EGC38283.1 - 6.1e-73 245.3 10.2 1.2e-72 244.3 10.2 1.5 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.17 EGC38283.1 - 8.5e-06 25.6 1.5 2e-05 24.4 1.5 1.6 1 0 0 1 1 1 1 Yip1 domain Spt20 PF12090.8 EGC38283.1 - 8.1 6.0 21.2 13 5.3 21.2 1.3 1 0 0 1 1 1 0 Spt20 family Cyt-b5 PF00173.28 EGC38284.1 - 4.2e-21 74.9 0.1 1.2e-20 73.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.21 EGC38284.1 - 2.9e-17 63.3 0.0 5.5e-17 62.4 0.0 1.5 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.24 EGC38284.1 - 6.2e-14 52.2 0.1 1.3e-13 51.1 0.1 1.5 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.12 EGC38284.1 - 3.2e-07 30.6 0.0 3.2e-07 30.6 0.0 2.5 2 1 0 3 3 3 1 Ferric reductase NAD binding domain UPF0147 PF03685.13 EGC38285.1 - 0.011 15.7 0.0 0.021 14.9 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Pox_A14 PF05767.12 EGC38285.1 - 0.012 15.7 4.1 0.012 15.7 4.1 1.9 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 7tm_1 PF00001.21 EGC38285.1 - 0.02 14.2 0.2 0.046 13.0 0.2 1.6 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Colicin_V PF02674.16 EGC38285.1 - 0.046 13.7 0.4 0.046 13.7 0.4 1.9 2 0 0 2 2 2 0 Colicin V production protein MAP17 PF15807.5 EGC38285.1 - 0.43 10.8 1.2 0.58 10.4 0.0 1.8 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 GATase PF00117.28 EGC38286.1 - 1.1e-17 64.4 0.0 1.6e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I HTS PF04204.16 EGC38286.1 - 3.7e-07 29.4 0.2 7.3e-07 28.4 0.2 1.6 1 1 0 1 1 1 1 Homoserine O-succinyltransferase Peptidase_C26 PF07722.13 EGC38286.1 - 3.4e-06 27.0 0.0 1.1e-05 25.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 GATase_3 PF07685.14 EGC38286.1 - 0.0034 17.0 0.0 0.0053 16.4 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain fragilysinNterm PF16376.5 EGC38286.1 - 0.0066 16.2 0.1 0.011 15.5 0.1 1.3 1 0 0 1 1 1 1 N-terminal domain of fragilysin PdaC PF13739.6 EGC38286.1 - 0.15 13.1 5.8 7.4 7.6 3.0 2.5 2 0 0 2 2 2 0 Deacetylase PdaC Ribosomal_L27A PF00828.19 EGC38289.1 - 5.1e-22 78.9 0.0 6.6e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A DUF5026 PF16429.5 EGC38289.1 - 0.18 11.9 0.2 0.34 11.0 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF5026) FNIP PF05725.12 EGC38291.1 - 2.9e-113 369.9 42.9 8.1e-17 61.1 4.4 9.3 6 1 3 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.13 EGC38291.1 - 0.011 16.1 0.0 31 5.0 0.0 4.5 2 1 2 4 4 4 0 Phage minor tail protein Peptidase_C21 PF05381.12 EGC38291.1 - 0.23 11.8 5.5 74 3.7 0.1 4.9 2 2 4 6 6 6 0 Tymovirus endopeptidase LRR_1 PF00560.33 EGC38291.1 - 8.7 7.3 16.1 31 5.6 0.2 7.3 6 2 1 7 7 7 0 Leucine Rich Repeat Regulator_TrmB PF11495.8 EGC38292.1 - 0.064 12.4 0.0 0.17 11.1 0.0 1.7 2 0 0 2 2 2 0 Archaeal transcriptional regulator TrmB DBD_Tnp_Hermes PF10683.9 EGC38292.1 - 0.13 12.0 0.3 1.1 9.0 0.0 2.4 2 1 0 2 2 2 0 Hermes transposase DNA-binding domain Med31 PF05669.12 EGC38292.1 - 0.86 9.6 4.9 0.99 9.4 2.7 2.3 2 0 0 2 2 2 0 SOH1 zinc_ribbon_15 PF17032.5 EGC38293.1 - 3.3e-10 40.6 0.2 6.6e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 zinc-ribbon family A2L_zn_ribbon PF08792.10 EGC38293.1 - 0.015 15.0 2.6 0.5 10.2 0.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain Asp_protease PF09668.10 EGC38294.1 - 5e-22 78.0 1.5 1.5e-21 76.5 0.6 2.1 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.23 EGC38294.1 - 9.1e-12 44.6 0.9 2.7e-11 43.1 0.9 1.8 1 0 0 1 1 1 1 Ubiquitin family gag-asp_proteas PF13975.6 EGC38294.1 - 1.8e-06 28.4 0.1 6.4e-06 26.6 0.0 2.0 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease UBA_4 PF14555.6 EGC38294.1 - 3.7e-05 23.4 0.0 7.8e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Rad60-SLD PF11976.8 EGC38294.1 - 4.8e-05 23.1 0.2 0.00016 21.4 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Mucin PF01456.17 EGC38294.1 - 0.0001 22.3 6.6 0.00017 21.6 6.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Rad60-SLD_2 PF13881.6 EGC38294.1 - 0.00031 20.8 1.0 0.00073 19.6 1.0 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3139 PF11337.8 EGC38294.1 - 0.0068 17.0 0.1 0.0068 17.0 0.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF3139) RVP PF00077.20 EGC38294.1 - 0.011 16.0 1.2 0.028 14.7 0.0 2.3 2 0 0 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.6 EGC38294.1 - 0.02 15.5 0.1 0.073 13.7 0.0 2.0 2 0 0 2 2 2 0 Aspartyl protease DUF2407 PF10302.9 EGC38294.1 - 0.065 13.8 2.5 0.35 11.5 0.7 2.5 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain TFIIA PF03153.13 EGC38294.1 - 0.067 13.2 18.2 0.034 14.2 11.0 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Pex14_N PF04695.13 EGC38294.1 - 0.087 13.5 15.4 1.2 9.8 4.3 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UN_NPL4 PF11543.8 EGC38294.1 - 0.095 13.2 0.2 0.34 11.4 0.2 2.0 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 Androgen_recep PF02166.16 EGC38294.1 - 1.3 7.8 8.8 2.5 6.8 8.8 1.4 1 0 0 1 1 1 0 Androgen receptor MGC-24 PF05283.11 EGC38294.1 - 3.5 8.1 11.5 8.6 6.8 11.5 1.6 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24), sialomucin zf-UBR PF02207.20 EGC38295.1 - 7.3e-13 48.5 17.0 7.3e-13 48.5 17.0 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.6 EGC38295.1 - 0.0067 16.7 3.0 0.0067 16.7 3.0 3.5 3 0 0 3 3 3 1 Ring finger domain TFB6 PF17110.5 EGC38295.1 - 3.2 7.5 10.3 7.9 6.2 10.3 1.6 1 0 0 1 1 1 0 Subunit 11 of the general transcription factor TFIIH zf-RING_2 PF13639.6 EGC38296.1 - 1.1e-05 25.7 10.1 1.1e-05 25.7 10.1 7.8 6 3 1 7 7 7 3 Ring finger domain zf-RING_11 PF17123.5 EGC38296.1 - 0.0072 16.1 8.7 0.0072 16.1 8.7 4.6 5 0 0 5 5 5 1 RING-like zinc finger zf-RING_5 PF14634.6 EGC38296.1 - 0.014 15.3 9.0 0.014 15.3 9.0 7.6 7 1 0 7 7 7 0 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC38296.1 - 0.016 15.3 3.1 0.016 15.3 3.1 6.7 7 1 0 7 7 7 0 RING-type zinc-finger zf-B_box PF00643.24 EGC38296.1 - 0.018 15.2 1.9 0.018 15.2 1.9 7.6 10 1 0 10 10 10 0 B-box zinc finger WH2 PF02205.20 EGC38297.1 - 1.1e-09 37.8 2.1 2e-09 37.0 2.1 1.5 1 0 0 1 1 1 1 WH2 motif AP-5_subunit_s1 PF15001.6 EGC38298.1 - 6.2e-26 91.6 1.9 1.4e-21 77.4 1.7 2.2 1 1 1 2 2 2 2 AP-5 complex subunit sigma-1 SUIM_assoc PF16619.5 EGC38298.1 - 8.6 6.5 24.8 0.11 12.5 3.4 2.8 1 1 1 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 RRM_1 PF00076.22 EGC38300.1 - 2.6e-20 72.0 0.2 3.6e-10 39.5 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.6 EGC38300.1 - 0.0048 16.5 1.6 0.015 14.9 1.0 2.1 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FBPase PF00316.20 EGC38302.1 - 1.4e-61 207.3 0.1 1.9e-61 206.9 0.1 1.2 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase, N-terminal domain Inositol_P PF00459.25 EGC38302.1 - 0.14 11.7 0.0 0.22 11.0 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family FAA_hydrolase PF01557.18 EGC38303.1 - 1.8e-56 191.2 0.0 2.1e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ketoacyl-synt PF00109.26 EGC38304.1 - 5.4e-48 163.8 0.1 7.9e-48 163.2 0.1 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC38304.1 - 3.4e-32 110.9 0.0 8.2e-32 109.7 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.23 EGC38304.1 - 0.015 14.6 1.0 0.026 13.9 0.5 1.5 1 1 0 1 1 1 0 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGC38304.1 - 0.02 14.6 2.1 0.11 12.2 0.1 3.0 3 1 0 3 3 3 0 Thiolase, C-terminal domain KAsynt_C_assoc PF16197.5 EGC38304.1 - 0.023 15.1 0.1 0.099 13.1 0.0 2.1 2 0 0 2 2 2 0 Ketoacyl-synthetase C-terminal extension WD40 PF00400.32 EGC38305.1 - 1.2e-15 57.6 12.6 0.00093 20.0 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38305.1 - 2.1e-12 47.1 1.9 2.6e-05 24.4 0.7 4.4 1 1 3 4 4 4 4 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC38305.1 - 3.2e-07 29.4 0.3 0.00047 18.9 0.3 2.2 2 0 0 2 2 2 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGC38305.1 - 1.5e-05 24.5 0.1 0.025 13.9 0.0 2.7 2 2 0 2 2 2 2 WD40-like domain BBS2_Mid PF14783.6 EGC38305.1 - 0.069 13.2 0.0 0.44 10.6 0.0 2.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region NARP1 PF12569.8 EGC38306.1 - 2.8e-123 412.6 27.3 1.2e-115 387.4 21.4 3.2 2 1 0 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.17 EGC38306.1 - 2.8e-18 64.5 22.5 0.00045 20.1 0.0 8.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.6 EGC38306.1 - 7.8e-16 57.4 0.7 0.38 11.7 0.0 8.9 6 2 4 10 10 10 3 Tetratricopeptide repeat TPR_16 PF13432.6 EGC38306.1 - 5.1e-11 43.0 0.0 0.087 13.5 0.0 7.0 7 1 1 8 8 7 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC38306.1 - 3.4e-10 40.1 8.9 0.071 13.4 0.0 7.5 8 2 0 8 8 8 3 Tetratricopeptide repeat TPR_7 PF13176.6 EGC38306.1 - 4e-07 29.6 5.1 0.033 14.2 0.0 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38306.1 - 6e-07 29.2 25.4 0.83 10.0 0.3 8.8 9 0 0 9 9 8 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGC38306.1 - 1.2e-06 28.0 32.6 0.002 17.9 0.2 7.6 9 0 0 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC38306.1 - 1.2e-06 28.4 12.6 0.005 16.9 0.0 5.9 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGC38306.1 - 5.6e-05 23.6 16.7 2.8 8.5 0.2 7.0 6 1 3 9 9 9 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC38306.1 - 8.8e-05 22.6 16.7 0.37 11.3 0.0 8.3 9 0 0 9 9 9 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC38306.1 - 0.00049 20.3 28.5 0.02 15.1 0.5 8.3 6 2 2 8 8 8 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.6 EGC38306.1 - 0.0078 16.8 16.4 4.7 8.1 0.1 8.7 11 0 0 11 11 9 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC38306.1 - 0.058 13.1 7.2 1.9 8.3 0.0 5.0 4 0 0 4 4 4 0 TPR repeat DUF627 PF04781.12 EGC38306.1 - 0.11 12.6 4.5 6.1 6.9 0.0 4.6 4 1 1 5 5 4 0 Protein of unknown function (DUF627) TPR_10 PF13374.6 EGC38306.1 - 0.13 12.2 11.0 3.3 7.7 0.2 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.20 EGC38306.1 - 0.16 12.3 0.2 3.9 7.9 0.0 3.2 3 0 0 3 3 3 0 PPR repeat DEAD PF00270.29 EGC38307.1 - 2.6e-46 157.6 0.0 5.2e-46 156.6 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC38307.1 - 3.7e-25 88.4 2.6 1.4e-24 86.6 0.0 3.3 4 0 0 4 4 4 1 Helicase conserved C-terminal domain DUF4217 PF13959.6 EGC38307.1 - 8.8e-16 57.9 0.0 1.9e-15 56.8 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) ResIII PF04851.15 EGC38307.1 - 2e-07 31.1 0.0 2e-07 31.1 0.0 4.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit ELMO_CED12 PF04727.13 EGC38308.1 - 1.4e-41 142.6 0.0 2.2e-41 141.9 0.0 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family SAM_KSR1 PF13543.6 EGC38308.1 - 0.021 14.9 1.5 0.19 11.9 0.0 2.5 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 SbsC_C PF18058.1 EGC38308.1 - 0.044 14.0 2.8 2.5 8.3 0.4 2.4 1 1 1 2 2 2 0 SbsC C-terminal domain DUF5388 PF17363.2 EGC38308.1 - 0.058 13.6 0.1 0.14 12.3 0.1 1.7 1 0 0 1 1 1 0 Family of unknown function (DUF5388) Dynactin_p62 PF05502.13 EGC38309.1 - 1.2e-33 116.7 22.2 5e-33 114.6 22.2 1.9 1 1 0 1 1 1 1 Dynactin p62 family OGG_N PF07934.12 EGC38310.1 - 5.7e-23 81.3 4.0 5.7e-23 81.3 4.0 2.1 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.25 EGC38310.1 - 8.3e-11 42.3 0.0 1.7e-10 41.3 0.0 1.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein 2-oxoacid_dh PF00198.23 EGC38311.1 - 3.1e-76 255.9 0.1 4.4e-76 255.4 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.22 EGC38311.1 - 1.8e-40 136.6 7.2 2e-20 72.4 0.4 2.4 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.17 EGC38311.1 - 1e-12 48.1 0.0 2.4e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.6 EGC38311.1 - 8.5e-10 38.3 0.0 4.6e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 Biotin-lipoyl like HlyD_3 PF13437.6 EGC38311.1 - 0.0003 21.5 0.2 0.91 10.3 0.0 2.9 2 0 0 2 2 2 2 HlyD family secretion protein PYNP_C PF07831.13 EGC38311.1 - 0.00094 18.8 0.9 2 8.1 0.0 3.1 3 0 0 3 3 3 2 Pyrimidine nucleoside phosphorylase C-terminal domain Peptidase_M23 PF01551.22 EGC38311.1 - 0.0025 18.0 0.5 2.2 8.6 0.0 3.0 3 0 0 3 3 3 2 Peptidase family M23 QRPTase_N PF02749.16 EGC38311.1 - 0.0037 17.3 0.1 0.57 10.3 0.0 2.7 2 0 0 2 2 2 1 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2118 PF09891.9 EGC38311.1 - 0.015 15.3 0.0 6.8 6.6 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) DUF4581 PF15167.6 EGC38311.1 - 0.024 14.8 0.0 0.73 10.0 0.0 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4581) GCV_H PF01597.19 EGC38311.1 - 0.033 14.1 3.1 4 7.4 0.1 3.2 2 2 1 3 3 3 0 Glycine cleavage H-protein CttA_N PF18244.1 EGC38311.1 - 0.085 13.3 0.1 17 5.9 0.0 2.7 2 0 0 2 2 2 0 Cellulose-binding protein CttA N-terminal domain HlyD_2 PF12700.7 EGC38311.1 - 0.091 11.5 3.4 1.4 7.5 0.2 3.2 3 1 1 4 4 4 0 HlyD family secretion protein HTH_Tnp_Tc5 PF03221.16 EGC38311.1 - 0.16 12.0 0.0 2.2 8.4 0.0 2.6 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain ubiquitin PF00240.23 EGC38312.1 - 1.8e-27 94.9 0.1 2e-27 94.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC38312.1 - 8.7e-16 57.5 0.2 9.4e-16 57.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC38312.1 - 2e-05 25.0 0.0 6.6e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC38312.1 - 0.00016 21.6 0.0 0.00019 21.3 0.0 1.1 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain HATPase_c PF02518.26 EGC38312.1 - 0.082 13.4 0.1 0.097 13.2 0.1 1.1 1 0 0 1 1 1 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ubiquitin_4 PF18036.1 EGC38312.1 - 0.11 12.5 0.3 7.9 6.6 0.3 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain Ala_racemase_N PF01168.20 EGC38313.1 - 1.6e-23 83.5 0.0 2e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DUF3909 PF13077.6 EGC38313.1 - 0.037 14.2 0.1 2.9 8.1 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3909) HIG_1_N PF04588.13 EGC38315.1 - 5.9e-10 39.2 0.0 7.6e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Hap4_Hap_bind PF10297.9 EGC38315.1 - 0.05 13.7 0.5 0.077 13.1 0.5 1.3 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Asp PF00026.23 EGC38316.1 - 1.7e-38 132.9 0.6 1.7e-38 132.9 0.6 1.8 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_N PF14543.6 EGC38316.1 - 2e-17 64.0 5.0 2e-17 64.0 5.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal TAXi_C PF14541.6 EGC38316.1 - 1.2e-09 38.2 0.0 2.1e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal ETRAMP PF09716.10 EGC38316.1 - 0.012 15.6 0.7 0.012 15.6 0.7 5.7 4 1 0 4 4 4 0 Malarial early transcribed membrane protein (ETRAMP) DUF3784 PF12650.7 EGC38316.1 - 0.025 14.8 0.6 3.6 7.9 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) EphA2_TM PF14575.6 EGC38316.1 - 0.13 13.2 0.4 6.3 7.7 0.0 3.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF3267 PF11667.8 EGC38316.1 - 6.3 7.1 7.9 0.31 11.4 2.0 1.8 2 0 0 2 2 2 0 Putative zincin peptidase GTP_EFTU PF00009.27 EGC38317.1 - 1.2e-55 188.1 0.2 2.3e-55 187.1 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.24 EGC38317.1 - 6.1e-14 51.8 0.0 2.4e-13 49.9 0.0 2.1 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.6 EGC38317.1 - 8.2e-10 38.6 0.1 2.1e-09 37.3 0.1 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.25 EGC38317.1 - 3.6e-08 33.7 0.0 1.2e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_IV PF03764.18 EGC38317.1 - 0.00011 22.0 0.1 0.0062 16.3 0.0 3.1 2 0 0 2 2 2 1 Elongation factor G, domain IV PPL5 PF18168.1 EGC38317.1 - 0.022 14.1 1.8 0.076 12.3 1.1 2.3 2 0 0 2 2 2 0 Prim-pol family 5 ATG27 PF09451.10 EGC38318.1 - 3.1e-28 99.4 0.4 4.1e-28 99.0 0.4 1.1 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.15 EGC38318.1 - 1.9e-13 50.1 4.4 2.6e-10 39.8 0.2 2.0 2 0 0 2 2 2 2 Mannose-6-phosphate receptor SNAP PF14938.6 EGC38320.1 - 2.1e-23 83.2 11.3 2.9e-23 82.7 11.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.6 EGC38320.1 - 0.0018 18.5 2.4 0.015 15.6 1.0 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat mTERF PF02536.14 EGC38320.1 - 0.018 14.0 0.1 0.026 13.5 0.1 1.2 1 0 0 1 1 1 0 mTERF TPR_10 PF13374.6 EGC38320.1 - 0.029 14.3 1.8 1.2 9.1 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Glyco_transf_9 PF01075.17 EGC38320.1 - 0.067 12.5 0.2 0.18 11.1 0.2 1.7 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Utp13 PF08625.11 EGC38320.1 - 0.22 11.4 2.0 15 5.5 0.2 2.5 2 1 0 2 2 2 0 Utp13 specific WD40 associated domain NSF PF02071.20 EGC38320.1 - 1.3 10.1 23.4 6.7 8.0 0.9 6.2 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.17 EGC38320.1 - 2.2 8.6 10.9 42 4.6 0.0 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat YihI PF04220.12 EGC38321.1 - 0.12 12.1 0.4 0.13 12.0 0.4 1.1 1 0 0 1 1 1 0 Der GTPase activator (YihI) Ribosomal_L35Ae PF01247.18 EGC38322.1 - 6.2e-37 125.6 0.0 7e-37 125.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae CENP-M PF11111.8 EGC38322.1 - 0.1 11.7 0.0 0.13 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere protein M (CENP-M) CDC45 PF02724.14 EGC38323.1 - 0.02 13.2 11.3 0.028 12.7 11.3 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.12 EGC38323.1 - 0.079 12.4 11.7 0.12 11.8 11.7 1.3 1 0 0 1 1 1 0 SDA1 Merozoite_SPAM PF07133.11 EGC38323.1 - 0.15 12.0 17.7 0.29 11.1 17.7 1.4 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) YL1 PF05764.13 EGC38323.1 - 0.5 10.5 10.9 0.74 9.9 10.9 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Presenilin PF01080.17 EGC38323.1 - 1.3 7.7 4.9 1.9 7.2 4.9 1.1 1 0 0 1 1 1 0 Presenilin Sporozoite_P67 PF05642.11 EGC38323.1 - 2.8 5.9 8.2 4 5.4 8.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Zip PF02535.22 EGC38323.1 - 7.9 5.6 10.2 12 5.0 10.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter ACBP PF00887.19 EGC38324.1 - 1.5e-26 92.5 2.9 1.6e-26 92.3 2.9 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.18 EGC38324.1 - 0.071 13.5 0.2 0.45 10.9 0.1 1.9 1 1 0 1 1 1 0 FERM central domain PGG PF13962.6 EGC38325.1 - 0.0024 17.7 2.8 0.014 15.2 1.1 2.4 2 0 0 2 2 2 1 Domain of unknown function DUF3522 PF12036.8 EGC38325.1 - 0.099 12.9 5.0 0.25 11.6 5.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3522) DUF2975 PF11188.8 EGC38325.1 - 9.2 6.2 7.4 0.98 9.3 2.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) COPI_assoc PF08507.10 EGC38326.1 - 1.1e-14 54.6 17.3 1.4e-14 54.3 17.3 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2371 PF10177.9 EGC38326.1 - 0.009 16.2 5.4 0.012 15.8 0.0 2.7 1 1 0 2 2 2 1 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.6 EGC38326.1 - 0.11 12.1 16.4 0.54 10.0 0.4 2.9 1 1 2 3 3 3 0 Neurensin DUF308 PF03729.13 EGC38326.1 - 1.4 9.3 29.3 0.64 10.4 18.7 2.3 2 0 0 2 2 2 0 Short repeat of unknown function (DUF308) DuoxA PF10204.9 EGC38326.1 - 1.8 7.5 13.1 3.5 6.6 5.1 2.4 2 1 0 2 2 2 0 Dual oxidase maturation factor FAM70 PF14967.6 EGC38326.1 - 4.2 6.7 7.6 5.2 6.4 7.6 1.2 1 0 0 1 1 1 0 FAM70 protein MRAP PF15183.6 EGC38326.1 - 9 6.3 8.0 25 4.9 0.0 2.8 2 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family CBM_20 PF00686.19 EGC38327.1 - 7.4e-17 61.1 0.1 1.5e-16 60.1 0.1 1.4 1 0 0 1 1 1 1 Starch binding domain zf-C3HC4_2 PF13923.6 EGC38327.1 - 1.8e-10 40.5 1.5 1.8e-10 40.5 1.5 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC38327.1 - 3.8e-09 36.4 4.5 3.8e-09 36.4 4.5 2.2 2 1 0 2 2 2 1 RING-type zinc-finger zf-C3HC4 PF00097.25 EGC38327.1 - 3.1e-08 33.4 0.6 3.1e-08 33.4 0.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGC38327.1 - 2.7e-07 30.6 0.0 4.9e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_2 PF13639.6 EGC38327.1 - 2.9e-07 30.7 2.7 2.9e-07 30.7 2.7 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38327.1 - 1.1e-06 28.4 0.8 2.7e-06 27.1 0.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38327.1 - 2e-06 28.0 1.7 2e-06 28.0 1.7 2.4 2 1 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC38327.1 - 2.7e-05 24.0 2.2 6.6e-05 22.7 2.0 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC38327.1 - 4.5e-05 23.5 1.8 4.5e-05 23.5 1.8 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC38327.1 - 4.7e-05 23.3 4.0 4.7e-05 23.3 4.0 2.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-Nse PF11789.8 EGC38327.1 - 0.0023 17.7 1.3 0.003 17.4 0.3 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TIG PF01833.24 EGC38328.1 - 1.6e-09 37.7 43.8 0.00011 22.2 8.4 5.8 5 2 0 6 6 6 4 IPT/TIG domain zf-RING_2 PF13639.6 EGC38330.1 - 2.3e-09 37.4 9.4 3.8e-09 36.7 9.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38330.1 - 6.5e-08 32.3 6.1 1.1e-07 31.6 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38330.1 - 1.7e-07 30.9 7.5 2.9e-07 30.2 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38330.1 - 3.5e-07 30.0 10.0 6.9e-07 29.0 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38330.1 - 1.9e-06 28.0 4.7 4.7e-06 26.8 4.7 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38330.1 - 0.00054 19.9 4.2 0.0011 19.0 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38330.1 - 0.00069 19.5 7.8 0.0012 18.7 7.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC38330.1 - 0.018 14.8 6.8 0.032 14.0 6.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.6 EGC38330.1 - 0.024 14.5 6.4 0.051 13.4 6.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC38330.1 - 0.03 14.4 0.5 0.073 13.1 0.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC38330.1 - 0.037 14.2 7.0 0.12 12.6 7.0 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC38330.1 - 0.06 13.1 6.6 0.077 12.8 5.4 1.9 1 1 1 2 2 2 0 RING-like zinc finger DUF1272 PF06906.11 EGC38330.1 - 0.073 13.2 5.7 0.14 12.2 5.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DZR PF12773.7 EGC38330.1 - 0.85 9.7 5.0 2.1 8.5 5.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon WRKY PF03106.15 EGC38331.1 - 3.4e-21 75.2 0.3 7.8e-21 74.1 0.3 1.7 1 0 0 1 1 1 1 WRKY DNA -binding domain Eryth_link_C PF16915.5 EGC38331.1 - 0.039 14.0 0.4 0.089 12.8 0.1 1.6 2 0 0 2 2 2 0 Annelid erythrocruorin linker subunit C-terminus WRKY PF03106.15 EGC38332.1 - 2.6e-24 85.2 8.2 2.9e-24 85.1 8.2 1.0 1 0 0 1 1 1 1 WRKY DNA -binding domain DEAD PF00270.29 EGC38333.1 - 2.2e-46 157.8 0.0 4.1e-46 156.9 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC38333.1 - 9.3e-31 106.5 0.6 4.6e-30 104.2 0.0 2.4 4 0 0 4 4 4 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC38333.1 - 4.5e-05 23.5 0.0 9.4e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_19 PF13245.6 EGC38333.1 - 0.012 16.0 0.0 0.031 14.6 0.0 1.7 1 1 0 1 1 1 0 AAA domain PWWP PF00855.17 EGC38334.1 - 1.4e-10 41.5 1.2 1.4e-10 41.5 1.2 2.7 3 0 0 3 3 3 1 PWWP domain Fe-S_biosyn PF01521.20 EGC38335.1 - 1.1e-15 57.8 0.2 1.4e-15 57.4 0.2 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis DSPc PF00782.20 EGC38336.1 - 1.5e-30 105.7 0.1 1.7e-30 105.6 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC38336.1 - 0.00016 21.3 0.0 0.00017 21.3 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.13 EGC38336.1 - 0.0057 16.7 0.0 0.45 10.6 0.0 2.1 2 0 0 2 2 2 1 Putative phosphatase (DUF442) BLYB PF05289.11 EGC38336.1 - 0.0058 16.8 0.5 0.0067 16.6 0.5 1.2 1 0 0 1 1 1 1 Borrelia hemolysin accessory protein Init_tRNA_PT PF04179.12 EGC38336.1 - 0.028 14.7 0.1 0.038 14.3 0.1 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain PTPlike_phytase PF14566.6 EGC38336.1 - 0.028 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Inositol hexakisphosphate Myotub-related PF06602.14 EGC38336.1 - 0.043 12.8 0.0 0.051 12.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4116 PF13475.6 EGC38336.1 - 0.12 12.1 2.1 0.88 9.4 0.6 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) ADH_zinc_N PF00107.26 EGC38336.1 - 0.2 11.6 0.0 0.28 11.2 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase zf-B_box PF00643.24 EGC38337.1 - 0.00031 20.8 12.3 0.00031 20.8 12.3 1.8 2 0 0 2 2 2 1 B-box zinc finger Sec10 PF07393.11 EGC38338.1 - 4.1e-83 280.1 14.7 9.9e-58 196.2 5.2 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 MotCF PF09158.10 EGC38338.1 - 0.58 10.2 3.7 1.9 8.6 1.1 2.7 2 1 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal EGF_2 PF07974.13 EGC38339.1 - 0.081 13.3 11.0 0.17 12.3 11.0 1.6 1 0 0 1 1 1 0 EGF-like domain Presenilin PF01080.17 EGC38340.1 - 2.9 6.5 11.6 4.4 6.0 11.6 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGC38340.1 - 3.5 7.6 5.6 5.7 6.9 5.6 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MFS_1_like PF12832.7 EGC38341.1 - 1.9e-113 379.2 22.1 2.4e-113 378.9 22.1 1.1 1 0 0 1 1 1 1 MFS_1 like family MFS_1 PF07690.16 EGC38341.1 - 9.1e-27 93.9 17.1 3.3e-26 92.1 13.0 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.16 EGC38341.1 - 1.3e-10 40.8 27.0 1.2e-09 37.7 10.2 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.19 EGC38341.1 - 2e-07 30.2 14.7 2e-07 30.2 14.7 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter MFS_2 PF13347.6 EGC38341.1 - 7.2 5.0 28.0 0.015 13.8 4.3 3.0 3 1 0 3 3 3 0 MFS/sugar transport protein MFS_1_like PF12832.7 EGC38342.1 - 1.4e-12 47.2 0.2 1.6e-12 47.0 0.2 1.0 1 0 0 1 1 1 1 MFS_1 like family MM_CoA_mutase PF01642.22 EGC38343.1 - 9.5e-236 783.3 0.2 1.1e-235 783.0 0.2 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.19 EGC38343.1 - 5.5e-17 61.9 0.0 1.3e-16 60.7 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain IMPDH PF00478.25 EGC38343.1 - 0.0028 16.7 0.2 0.0058 15.7 0.0 1.5 2 0 0 2 2 2 1 IMP dehydrogenase / GMP reductase domain IF2_N PF04760.15 EGC38343.1 - 0.011 15.6 0.1 8.2 6.3 0.0 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3461 PF11944.8 EGC38343.1 - 0.025 14.7 0.9 0.076 13.2 0.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3461) ThiF PF00899.21 EGC38344.1 - 6e-71 238.7 0.0 9.2e-71 238.0 0.0 1.2 1 0 0 1 1 1 1 ThiF family UAE_UbL PF14732.6 EGC38344.1 - 1e-18 67.7 1.0 2.7e-18 66.3 1.0 1.8 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain UBA_e1_thiolCys PF10585.9 EGC38344.1 - 1.9e-06 28.0 14.3 0.00057 19.9 0.6 3.4 2 1 1 3 3 3 2 Ubiquitin-activating enzyme active site NAD_binding_7 PF13241.6 EGC38344.1 - 9.1e-05 22.9 1.3 0.00056 20.3 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.20 EGC38344.1 - 0.0034 17.4 0.0 0.0072 16.4 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase RNA_pol_Rbc25 PF08292.12 EGC38344.1 - 3.2 8.0 6.8 0.72 10.1 2.9 2.0 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 Sacchrp_dh_NADP PF03435.18 EGC38344.1 - 6 7.1 7.0 1.9 8.8 0.9 3.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain DUF1127 PF06568.11 EGC38345.1 - 0.95 9.2 2.3 1.4 8.7 2.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DUF3439 PF11921.8 EGC38345.1 - 3.3 7.7 13.7 7.8 6.5 13.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FNIP PF05725.12 EGC38346.1 - 1.6e-140 457.1 45.7 1.8e-13 50.4 0.2 12.6 6 3 4 13 13 13 13 FNIP Repeat Peptidase_C21 PF05381.12 EGC38346.1 - 0.65 10.4 13.0 11 6.4 0.3 5.3 2 2 1 4 4 4 0 Tymovirus endopeptidase zf-RVT PF13966.6 EGC38347.1 - 1.1e-05 26.1 2.2 2.6e-05 24.9 0.8 2.3 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase DUF1600 PF07667.11 EGC38347.1 - 0.02 15.1 1.4 0.091 13.0 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1600) Peptidase_A22B PF04258.13 EGC38348.1 - 5.4e-48 164.0 18.3 8.3e-48 163.3 18.3 1.2 1 0 0 1 1 1 1 Signal peptide peptidase DUF5336 PF17270.2 EGC38348.1 - 0.023 14.3 0.7 0.043 13.4 0.5 1.6 1 1 0 1 1 1 0 Family of unknown function (DUF5336) AcetylCoA_hyd_C PF13336.6 EGC38349.1 - 3.9e-36 124.3 0.0 5.7e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.15 EGC38349.1 - 6.7e-33 114.3 0.0 1.1e-32 113.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.12 EGC38349.1 - 0.082 11.8 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) TMEM154 PF15102.6 EGC38350.1 - 0.0058 16.5 0.1 0.0058 16.5 0.1 1.7 2 0 0 2 2 2 1 TMEM154 protein family DUF4369 PF14289.6 EGC38350.1 - 0.086 13.4 4.4 0.4 11.2 3.0 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4369) Orf78 PF06024.12 EGC38351.1 - 0.0076 16.5 0.4 0.023 15.0 0.4 1.8 1 0 0 1 1 1 1 Orf78 (ac78) TMEM154 PF15102.6 EGC38351.1 - 0.0094 15.9 0.4 0.0094 15.9 0.4 1.9 2 0 0 2 2 2 1 TMEM154 protein family Oxysterol_BP PF01237.18 EGC38351.1 - 0.012 14.4 1.1 0.02 13.7 1.1 1.4 1 0 0 1 1 1 0 Oxysterol-binding protein MMS19_N PF14500.6 EGC38352.1 - 1.4e-74 250.9 10.9 5.9e-59 199.8 0.3 4.9 3 2 1 4 4 4 3 Dos2-interacting transcription regulator of RNA-Pol-II MMS19_C PF12460.8 EGC38352.1 - 2e-55 188.7 29.4 2e-55 188.7 29.4 4.4 2 2 1 4 4 4 1 RNAPII transcription regulator C-terminal Vac14_Fab1_bd PF12755.7 EGC38352.1 - 4.8e-05 23.9 5.8 0.0077 16.8 0.1 5.1 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.6 EGC38352.1 - 0.0022 18.4 0.0 3.4 8.1 0.0 3.8 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EGC38352.1 - 0.023 15.2 0.1 1e+02 3.6 0.0 4.9 5 1 1 6 6 6 0 HEAT-like repeat DUF4226 PF10774.9 EGC38352.1 - 0.16 12.2 0.0 0.55 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4226) HEAT PF02985.22 EGC38352.1 - 0.3 11.5 4.3 80 3.9 0.0 5.6 6 0 0 6 6 6 0 HEAT repeat Telomere_reg-2 PF10193.9 EGC38352.1 - 4.4 7.8 13.3 4.2 7.9 0.2 4.9 5 0 0 5 5 5 0 Telomere length regulation protein Spidroin_MaSp PF11260.8 EGC38352.1 - 7.9 6.9 10.5 2.9 8.3 0.1 4.5 5 0 0 5 5 5 0 Major ampullate spidroin 1 and 2 PLAC8 PF04749.17 EGC38353.1 - 8.7e-13 49.1 19.3 1.1e-12 48.8 19.3 1.1 1 0 0 1 1 1 1 PLAC8 family GIDA PF01134.22 EGC38354.1 - 5.6e-152 506.4 0.3 8.5e-152 505.8 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc PF13932.6 EGC38354.1 - 2.6e-62 210.7 0.6 4e-62 210.1 0.6 1.3 1 0 0 1 1 1 1 GidA associated domain Pyr_redox_2 PF07992.14 EGC38354.1 - 2.8e-05 23.5 0.6 7.7e-05 22.1 0.6 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.7 EGC38354.1 - 0.00031 20.2 0.2 0.00051 19.5 0.2 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.21 EGC38354.1 - 0.0043 16.4 3.2 0.08 12.2 2.2 2.3 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain FAD_binding_2 PF00890.24 EGC38354.1 - 0.044 12.9 4.1 0.061 12.4 1.9 2.1 2 0 0 2 2 2 0 FAD binding domain HI0933_like PF03486.14 EGC38354.1 - 0.096 11.4 3.2 2.7 6.6 1.3 3.1 3 0 0 3 3 3 0 HI0933-like protein Ribosomal_L39 PF00832.20 EGC38355.1 - 3.7e-22 77.7 7.0 4.3e-22 77.5 7.0 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein MgsA_C PF12002.8 EGC38356.1 - 1e-53 181.7 0.0 1e-53 181.7 0.0 2.5 3 0 0 3 3 2 1 MgsA AAA+ ATPase C terminal AAA_assoc_2 PF16193.5 EGC38356.1 - 1.1e-20 73.8 0.2 3.1e-20 72.3 0.2 1.9 1 0 0 1 1 1 1 AAA C-terminal domain AAA PF00004.29 EGC38356.1 - 2.9e-19 69.8 0.1 6.6e-19 68.7 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.12 EGC38356.1 - 4e-17 62.4 0.5 6.9e-17 61.6 0.0 1.6 2 0 0 2 2 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGC38356.1 - 1.3e-08 34.9 0.2 1.1e-07 31.9 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.6 EGC38356.1 - 1.2e-07 31.8 2.2 1.6e-07 31.5 0.0 2.4 2 0 0 2 2 1 1 AAA domain NB-ARC PF00931.22 EGC38356.1 - 4.1e-07 29.5 0.1 0.00045 19.5 0.0 2.3 1 1 1 2 2 2 2 NB-ARC domain Sigma54_activat PF00158.26 EGC38356.1 - 5.8e-07 29.4 0.0 0.00056 19.6 0.0 2.3 1 1 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGC38356.1 - 1.9e-06 28.0 0.0 9.1e-06 25.8 0.0 2.0 2 0 0 2 2 2 1 Sigma-54 interaction domain Mg_chelatase PF01078.21 EGC38356.1 - 2.6e-06 27.0 0.1 0.013 14.9 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.6 EGC38356.1 - 1.4e-05 25.6 0.0 0.00098 19.5 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.18 EGC38356.1 - 2.2e-05 24.3 0.0 7.6e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase ATPase_2 PF01637.18 EGC38356.1 - 4e-05 23.6 0.9 0.005 16.8 0.0 3.0 1 1 1 2 2 2 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EGC38356.1 - 0.00014 22.4 0.0 0.00014 22.4 0.0 3.8 4 1 0 4 4 2 1 AAA domain AAA_22 PF13401.6 EGC38356.1 - 0.00076 19.8 0.1 0.0061 16.8 0.1 2.2 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.12 EGC38356.1 - 0.0012 18.2 0.0 0.0026 17.1 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin MCM PF00493.23 EGC38356.1 - 0.0014 17.8 0.0 0.004 16.3 0.0 1.7 1 1 0 1 1 1 1 MCM P-loop domain AAA_24 PF13479.6 EGC38356.1 - 0.0029 17.3 0.0 0.0059 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.14 EGC38356.1 - 0.0048 17.0 0.0 0.018 15.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.13 EGC38356.1 - 0.0061 15.8 0.0 0.02 14.1 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGC38356.1 - 0.0076 16.8 0.0 0.0076 16.8 0.0 3.4 3 1 1 4 4 2 1 ABC transporter ATP-synt_ab PF00006.25 EGC38356.1 - 0.014 15.1 0.0 0.033 13.8 0.0 1.5 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.6 EGC38356.1 - 0.015 15.7 0.3 2.7 8.3 0.1 2.5 1 1 1 2 2 2 0 AAA domain AAA_33 PF13671.6 EGC38356.1 - 0.019 15.1 0.0 0.05 13.8 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC38356.1 - 0.026 14.8 0.0 0.055 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC38356.1 - 0.027 14.4 0.1 0.078 12.9 0.0 1.8 2 0 0 2 2 1 0 NACHT domain AAA_17 PF13207.6 EGC38356.1 - 0.036 14.5 1.7 0.062 13.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGC38356.1 - 0.038 13.7 0.0 0.084 12.6 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein UBZ_FAAP20 PF15750.5 EGC38356.1 - 0.042 13.8 0.4 0.091 12.7 0.4 1.5 1 0 0 1 1 1 0 Ubiquitin-binding zinc-finger DUF5333 PF17267.2 EGC38356.1 - 0.071 13.3 0.1 0.22 11.7 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5333) Cytidylate_kin PF02224.18 EGC38356.1 - 0.09 12.5 0.2 0.23 11.2 0.1 1.7 2 0 0 2 2 1 0 Cytidylate kinase AAA_3 PF07726.11 EGC38356.1 - 0.1 12.5 0.0 0.42 10.5 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGC38356.1 - 0.19 11.4 0.0 2 8.1 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_25 PF13481.6 EGC38356.1 - 0.48 10.0 0.0 0.48 10.0 0.0 1.7 2 0 0 2 2 1 0 AAA domain TRAF6_Z2 PF18048.1 EGC38356.1 - 6.4 7.0 6.8 0.5 10.5 1.6 1.9 2 0 0 2 2 1 0 TNF receptor-associated factor 6 zinc finger 2 PAH PF02671.21 EGC38357.1 - 2.3e-06 27.6 0.2 2.3e-06 27.6 0.2 2.2 2 2 0 2 2 2 1 Paired amphipathic helix repeat DUF3713 PF12506.8 EGC38357.1 - 0.036 14.4 2.6 0.039 14.2 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) TMPIT PF07851.13 EGC38357.1 - 0.037 13.3 0.8 0.043 13.1 0.8 1.1 1 0 0 1 1 1 0 TMPIT-like protein Rsd_AlgQ PF04353.13 EGC38357.1 - 0.071 13.1 1.2 0.16 11.9 1.2 1.6 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Ras PF00071.22 EGC38358.1 - 1.5e-13 50.7 0.7 1.5e-13 50.7 0.7 2.0 2 1 0 2 2 2 1 Ras family Roc PF08477.13 EGC38358.1 - 4.9e-07 30.0 2.3 5.5e-07 29.8 0.1 2.3 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38358.1 - 7.5e-07 28.8 0.2 2.9e-06 26.9 0.2 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family TniB PF05621.11 EGC38358.1 - 0.00055 19.4 0.8 0.37 10.2 0.1 2.6 2 1 0 3 3 3 2 Bacterial TniB protein DTC PF18102.1 EGC38358.1 - 0.012 15.7 4.5 0.038 14.1 3.2 2.5 2 1 0 2 2 2 0 Deltex C-terminal domain FtsK_SpoIIIE PF01580.18 EGC38358.1 - 0.029 13.7 0.1 0.064 12.6 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF3439 PF11921.8 EGC38358.1 - 0.19 11.7 5.8 0.39 10.7 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.6 EGC38359.1 - 5.3e-10 39.5 10.8 8.3e-10 38.8 10.8 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC38359.1 - 3.8e-08 33.1 11.5 6.8e-08 32.3 11.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC38359.1 - 5.5e-08 32.5 7.5 8.9e-08 31.9 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38359.1 - 6.1e-08 32.4 9.3 9.9e-08 31.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38359.1 - 3e-07 30.6 6.4 6.4e-07 29.6 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC38359.1 - 0.00013 21.8 10.1 0.00023 21.0 10.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC38359.1 - 0.00047 20.1 5.9 0.00088 19.2 5.9 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGC38359.1 - 0.00083 19.4 1.8 0.0015 18.5 1.8 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EGC38359.1 - 0.0091 16.1 5.7 0.017 15.2 5.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.6 EGC38359.1 - 0.012 15.5 7.3 0.024 14.5 7.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC38359.1 - 0.013 15.3 9.0 0.025 14.3 9.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGC38359.1 - 0.026 14.7 9.9 0.095 12.9 9.9 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC38359.1 - 0.1 12.4 8.2 0.3 10.9 8.2 1.9 1 0 0 1 1 1 0 RING-like zinc finger DZR PF12773.7 EGC38359.1 - 0.23 11.5 5.3 0.46 10.6 5.3 1.5 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_9 PF14369.6 EGC38359.1 - 8.3 6.8 9.8 2.4 8.5 6.2 2.0 2 1 0 2 2 1 0 zinc-ribbon Zip PF02535.22 EGC38360.1 - 0.099 11.8 4.1 0.12 11.6 4.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC38360.1 - 0.1 11.4 7.4 0.12 11.1 7.4 1.2 1 0 0 1 1 1 0 Presenilin Dicty_REP PF05086.12 EGC38360.1 - 0.16 10.0 13.5 0.19 9.7 13.5 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein OAD_gamma PF04277.13 EGC38360.1 - 0.18 12.4 1.4 0.68 10.6 1.4 2.0 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain CLN3 PF02487.17 EGC38360.1 - 0.53 9.3 3.4 0.67 8.9 3.4 1.3 1 0 0 1 1 1 0 CLN3 protein SOG2 PF10428.9 EGC38360.1 - 0.6 9.2 16.5 0.61 9.2 16.5 1.0 1 0 0 1 1 1 0 RAM signalling pathway protein EOS1 PF12326.8 EGC38360.1 - 0.73 9.7 3.4 0.98 9.3 3.4 1.3 1 0 0 1 1 1 0 N-glycosylation protein DUF4834 PF16118.5 EGC38360.1 - 0.93 10.5 16.0 2.3e+02 2.8 16.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4834) HCO3_cotransp PF00955.21 EGC38360.1 - 1.1 8.0 5.8 1.3 7.8 5.8 1.1 1 0 0 1 1 1 0 HCO3- transporter family Nodulin_late PF07127.11 EGC38360.1 - 1.1 9.6 2.9 0.87 10.0 1.2 1.7 2 0 0 2 2 2 0 Late nodulin protein O-antigen_lig PF13425.6 EGC38360.1 - 1.6 7.4 8.2 1.8 7.3 8.2 1.1 1 0 0 1 1 1 0 O-antigen ligase like membrane protein TFIIA PF03153.13 EGC38360.1 - 3.3 7.6 22.4 4 7.3 22.4 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Connexin PF00029.19 EGC38360.1 - 3.7 7.2 5.8 13 5.4 5.8 1.7 1 1 0 1 1 1 0 Connexin EphA2_TM PF14575.6 EGC38360.1 - 6.9 7.6 5.5 2.1e+02 2.9 5.5 2.2 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Ndc1_Nup PF09531.10 EGC38360.1 - 7.6 5.1 10.4 8.6 4.9 10.4 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FNIP PF05725.12 EGC38361.1 - 4.6e-120 391.6 17.0 1.9e-15 56.7 0.0 8.0 3 2 6 10 10 10 10 FNIP Repeat SPATA6 PF14909.6 EGC38361.1 - 2.4e-05 24.5 0.0 14 5.8 0.0 5.8 1 1 4 6 6 6 1 Spermatogenesis-assoc protein 6 Phage_min_tail PF05939.13 EGC38361.1 - 0.0029 18.0 1.0 1.2e+02 3.1 0.0 6.0 2 1 6 9 9 9 0 Phage minor tail protein Aft1_OSA PF11785.8 EGC38361.1 - 0.035 14.6 8.0 47 4.5 0.0 5.4 4 2 2 6 6 6 0 Aft1 osmotic stress response (OSM) domain HTH_29 PF13551.6 EGC38363.1 - 6.4e-06 26.1 0.2 2.3e-05 24.3 0.1 1.9 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 EGC38363.1 - 2e-05 24.3 0.1 4.2e-05 23.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGC38363.1 - 0.00014 21.9 0.2 0.00026 21.0 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_50 PF18024.1 EGC38363.1 - 0.00031 20.3 1.1 0.00057 19.4 1.1 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_38 PF13936.6 EGC38363.1 - 0.00064 19.4 0.3 0.00064 19.4 0.3 1.8 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_32 PF13565.6 EGC38363.1 - 0.013 16.1 0.1 0.74 10.5 0.1 2.3 1 1 1 2 2 2 0 Homeodomain-like domain HTH_36 PF13730.6 EGC38363.1 - 0.019 14.9 0.2 0.037 14.0 0.2 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PAX PF00292.18 EGC38363.1 - 0.031 14.2 0.0 0.073 13.0 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain HTH_Tnp_Tc3_2 PF01498.18 EGC38363.1 - 0.037 14.3 1.4 0.075 13.3 0.2 1.9 2 0 0 2 2 2 0 Transposase TrmB PF01978.19 EGC38363.1 - 0.067 13.1 0.8 0.23 11.4 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_AsnC-type PF13404.6 EGC38363.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Sigma70_r4_2 PF08281.12 EGC38363.1 - 0.15 11.8 0.1 0.25 11.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 I_LWEQ PF01608.17 EGC38365.1 - 3.6e-68 228.6 188.3 6.6e-47 159.6 6.7 20.3 5 4 13 20 20 20 14 I/LWEQ domain FERM_f0 PF16511.5 EGC38365.1 - 9.7e-33 112.3 0.9 7.5e-27 93.5 0.1 4.2 4 0 0 4 4 4 2 N-terminal or F0 domain of Talin-head FERM FERM_M PF00373.18 EGC38365.1 - 3.6e-28 98.3 0.0 3.1e-27 95.3 0.0 2.8 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.10 EGC38365.1 - 9.1e-21 73.6 0.2 2.6e-17 62.5 0.1 2.7 2 0 0 2 2 2 2 FERM N-terminal domain VHP PF02209.19 EGC38365.1 - 1.7e-15 56.7 0.5 4.7e-15 55.4 0.5 1.8 1 0 0 1 1 1 1 Villin headpiece domain VBS PF08913.10 EGC38365.1 - 0.00022 21.6 4.1 0.00022 21.6 4.1 13.3 12 4 1 14 14 14 5 Vinculin Binding Site ACBP PF00887.19 EGC38365.1 - 0.001 19.2 0.0 0.0067 16.6 0.0 2.6 1 0 0 1 1 1 1 Acyl CoA binding protein PB1 PF00564.24 EGC38365.1 - 0.03 14.3 0.3 6 6.9 0.0 3.8 3 0 0 3 3 3 0 PB1 domain DUF2935 PF11155.8 EGC38365.1 - 3 8.2 20.3 1.4 9.3 0.4 8.1 6 3 1 7 7 7 0 Domain of unknown function (DUF2935) Staph_haemo PF05480.11 EGC38365.1 - 3.2 7.6 5.4 38 4.2 0.3 4.4 3 0 0 3 3 3 0 Staphylococcus haemolytic protein LAS2 PF15792.5 EGC38365.1 - 6.2 7.4 8.5 2.6 8.6 2.8 3.3 2 0 0 2 2 2 0 Lung adenoma susceptibility protein 2 PIF1 PF05970.14 EGC38366.1 - 0.043 13.0 1.9 0.076 12.2 1.9 1.4 1 1 0 1 1 1 0 PIF1-like helicase PTPS PF01242.19 EGC38366.1 - 0.075 13.0 0.5 0.089 12.8 0.5 1.3 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase PP2C_C PF07830.13 EGC38366.1 - 0.16 12.5 0.5 22 5.6 0.4 2.3 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain hDGE_amylase PF14701.6 EGC38367.1 - 1.1e-165 552.0 1.0 1.8e-165 551.4 1.0 1.3 1 0 0 1 1 1 1 Glycogen debranching enzyme, glucanotransferase domain GDE_C PF06202.14 EGC38367.1 - 4.7e-109 364.8 0.0 8.8e-109 363.9 0.0 1.4 1 0 0 1 1 1 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.6 EGC38367.1 - 3.4e-66 223.5 0.2 6.9e-66 222.5 0.2 1.5 1 0 0 1 1 1 1 Central domain of human glycogen debranching enzyme hGDE_N PF14699.6 EGC38367.1 - 2.7e-07 30.6 0.1 7.2e-07 29.3 0.1 1.8 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme Alpha-amylase PF00128.24 EGC38367.1 - 0.024 14.2 0.2 0.056 13.0 0.2 1.5 1 0 0 1 1 1 0 Alpha amylase, catalytic domain Abhydrolase_4 PF08386.10 EGC38367.1 - 0.069 13.3 0.0 0.16 12.1 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Peptidase_C1 PF00112.23 EGC38368.1 - 0.0012 18.9 0.1 0.0025 17.9 0.0 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1 PF00112.23 EGC38369.1 - 1.2e-05 25.5 0.2 2.3e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.23 EGC38370.1 - 0.16 12.0 0.0 0.29 11.2 0.0 1.5 1 1 0 1 1 1 0 Papain family cysteine protease Proteasom_Rpn13 PF04683.13 EGC38371.1 - 1.9e-05 25.1 0.0 6.4e-05 23.4 0.0 1.9 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor VWA_2 PF13519.6 EGC38372.1 - 2.6e-05 24.8 0.1 0.00011 22.8 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain Telomere_reg-2 PF10193.9 EGC38373.1 - 3.6e-28 98.2 0.0 1.8e-27 96.0 0.0 2.3 1 0 0 1 1 1 1 Telomere length regulation protein Glyco_hydro_20 PF00728.22 EGC38374.1 - 1.1e-77 261.8 0.3 1.7e-75 254.6 0.0 2.9 2 1 0 2 2 2 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.6 EGC38374.1 - 4.5e-16 59.7 0.2 2.3e-15 57.5 0.1 2.2 2 0 0 2 2 2 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.15 EGC38374.1 - 4.2e-05 24.3 0.0 7.9e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 AP_endonuc_2 PF01261.24 EGC38374.1 - 0.024 14.1 0.1 0.83 9.1 0.0 2.1 1 1 0 2 2 2 0 Xylose isomerase-like TIM barrel ABC_membrane PF00664.23 EGC38375.1 - 2e-69 234.3 42.0 2.7e-40 138.8 19.0 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC38375.1 - 7.6e-46 156.0 6.0 4e-30 105.1 0.0 3.4 4 0 0 4 4 3 2 ABC transporter SMC_N PF02463.19 EGC38375.1 - 4.2e-05 23.1 18.7 0.042 13.3 0.1 5.0 4 2 1 6 6 6 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.6 EGC38375.1 - 0.0002 21.0 2.0 0.37 10.6 0.2 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain PduV-EutP PF10662.9 EGC38375.1 - 0.0027 17.5 0.3 1.4 8.6 0.0 3.0 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.6 EGC38375.1 - 0.011 16.0 0.8 4.7 7.5 0.3 3.3 3 0 0 3 3 3 0 AAA domain MMR_HSR1 PF01926.23 EGC38375.1 - 0.014 15.4 0.3 3.3 7.8 0.1 3.3 3 0 0 3 3 3 0 50S ribosome-binding GTPase DUF3270 PF11674.8 EGC38375.1 - 0.041 14.1 0.1 0.041 14.1 0.1 3.0 3 0 0 3 3 1 0 Protein of unknown function (DUF3270) T2SSE PF00437.20 EGC38375.1 - 0.043 12.9 0.1 5.4 6.0 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.18 EGC38375.1 - 0.077 12.3 1.5 2.1 7.6 0.1 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.9 EGC38375.1 - 0.095 11.6 0.5 6.7 5.5 0.0 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EGC38375.1 - 0.19 12.1 3.3 12 6.3 0.2 3.1 2 1 0 2 2 2 0 AAA ATPase domain AAA PF00004.29 EGC38375.1 - 0.22 11.9 0.8 9.4 6.7 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Frag1 PF10277.9 EGC38376.1 - 8.4e-50 169.3 11.9 9.5e-50 169.1 11.9 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tmemb_18A PF09771.9 EGC38376.1 - 0.45 10.9 2.0 0.55 10.6 0.1 2.0 2 0 0 2 2 2 0 Transmembrane protein 188 RRM_1 PF00076.22 EGC38377.1 - 4.1e-21 74.6 0.0 6.2e-21 74.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC38377.1 - 0.0032 17.4 0.0 0.0058 16.6 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.6 EGC38377.1 - 0.034 13.7 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC38377.1 - 0.037 13.9 0.0 0.076 12.9 0.0 1.5 1 1 0 1 1 1 0 Occluded RNA-recognition motif Syntaxin_2 PF14523.6 EGC38378.1 - 1.6e-22 79.7 6.6 1.6e-22 79.7 6.6 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.19 EGC38378.1 - 1.5e-12 47.3 0.3 1.5e-12 47.3 0.3 1.9 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.25 EGC38378.1 - 2.8e-06 27.1 11.7 9.4e-06 25.4 2.0 2.7 2 1 0 2 2 2 2 Syntaxin T2SSF PF00482.23 EGC38378.1 - 0.026 14.5 0.3 0.55 10.2 0.2 2.3 2 0 0 2 2 2 0 Type II secretion system (T2SS), protein F PLDc_N PF13396.6 EGC38378.1 - 0.028 14.4 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Pox_EPC_I2-L1 PF12575.8 EGC38378.1 - 0.074 13.3 0.1 0.15 12.3 0.1 1.5 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 Caldesmon PF02029.15 EGC38378.1 - 0.2 10.4 10.0 0.28 9.9 10.0 1.1 1 0 0 1 1 1 0 Caldesmon DUF1084 PF06454.11 EGC38379.1 - 1.5e-12 47.5 25.3 2.6e-12 46.7 25.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) WD40 PF00400.32 EGC38380.1 - 6.4e-17 61.6 9.9 0.00018 22.2 0.0 6.4 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38380.1 - 2e-09 37.6 0.3 0.67 10.3 0.0 5.3 3 3 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Nup160 PF11715.8 EGC38380.1 - 0.00012 20.8 0.6 0.089 11.4 0.0 3.4 3 1 1 4 4 4 2 Nucleoporin Nup120/160 WD40_like PF17005.5 EGC38380.1 - 0.0063 15.9 0.7 0.058 12.7 0.0 2.4 3 0 0 3 3 3 1 WD40-like domain Hira PF07569.11 EGC38380.1 - 0.023 14.4 0.2 12 5.6 0.0 3.0 2 1 1 3 3 3 0 TUP1-like enhancer of split eIF2A PF08662.11 EGC38380.1 - 0.092 12.6 0.3 3 7.7 0.0 3.0 4 0 0 4 4 4 0 Eukaryotic translation initiation factor eIF2A ERM PF00769.19 EGC38381.1 - 0.0091 15.8 12.9 0.011 15.5 12.9 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family DUF2115 PF09888.9 EGC38381.1 - 0.016 15.7 3.8 0.019 15.5 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) PKcGMP_CC PF16808.5 EGC38381.1 - 0.049 13.5 1.5 0.049 13.5 1.5 3.4 1 1 3 4 4 4 0 Coiled-coil N-terminus of cGMP-dependent protein kinase DUF2203 PF09969.9 EGC38381.1 - 0.094 13.4 5.2 0.14 12.9 5.2 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) V_ATPase_I PF01496.19 EGC38381.1 - 0.16 9.8 7.4 0.18 9.7 7.4 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Atg14 PF10186.9 EGC38381.1 - 0.94 8.5 9.5 1.3 8.1 9.5 1.3 1 0 0 1 1 1 0 Vacuolar sorting 38 and autophagy-related subunit 14 FAM76 PF16046.5 EGC38381.1 - 1.1 8.5 8.6 1.2 8.4 8.6 1.1 1 0 0 1 1 1 0 FAM76 protein FapA PF03961.13 EGC38381.1 - 1.2 7.7 10.8 1.4 7.5 10.8 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TMPIT PF07851.13 EGC38381.1 - 4.6 6.4 6.7 5.3 6.2 6.7 1.1 1 0 0 1 1 1 0 TMPIT-like protein TMF_DNA_bd PF12329.8 EGC38381.1 - 5.5 7.1 19.5 0.35 10.9 9.2 3.2 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding DUF1542 PF07564.11 EGC38381.1 - 7.7 6.7 10.5 0.34 11.1 4.8 1.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1542) Atg8 PF02991.16 EGC38382.1 - 4e-34 116.9 0.2 4.7e-34 116.7 0.2 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.13 EGC38382.1 - 0.00015 22.1 0.1 0.00022 21.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Arm PF00514.23 EGC38383.1 - 0.00026 20.9 0.3 2.6 8.2 0.0 5.1 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat IMUP PF15761.5 EGC38384.1 - 7.1 7.4 14.5 8.7 7.1 1.8 3.0 2 0 0 2 2 2 0 Immortalisation up-regulated protein FNIP PF05725.12 EGC38386.1 - 3e-163 529.9 50.3 8.3e-17 61.1 1.2 12.6 10 1 2 13 13 13 13 FNIP Repeat K1 PF02960.14 EGC38386.1 - 0.023 14.8 0.1 26 5.0 0.0 4.3 4 2 2 6 6 6 0 K1 glycoprotein SSURE PF11966.8 EGC38386.1 - 0.027 14.2 11.3 27 4.6 0.0 7.7 6 3 3 10 10 10 0 Fibronectin-binding repeat LRR_5 PF13306.6 EGC38386.1 - 0.076 13.0 6.2 1.6 8.7 0.2 5.1 2 2 1 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Tox-MPTase3 PF15639.6 EGC38388.1 - 0.02 14.7 0.1 0.049 13.5 0.1 1.7 1 0 0 1 1 1 0 Metallopeptidase toxin 3 Orf78 PF06024.12 EGC38388.1 - 1.5 9.1 5.9 0.095 13.0 0.5 1.8 2 0 0 2 2 2 0 Orf78 (ac78) FNIP PF05725.12 EGC38390.1 - 5.3e-131 426.6 46.8 5e-15 55.4 0.1 11.0 10 1 1 11 11 11 10 FNIP Repeat DUF3215 PF11503.8 EGC38390.1 - 0.00076 19.3 0.1 48 3.9 0.0 6.7 5 0 0 5 5 5 1 Protein of unknown function (DUF3215) TAP_C PF03943.13 EGC38392.1 - 9.8e-12 44.3 1.1 2.1e-11 43.3 1.1 1.6 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.20 EGC38392.1 - 3.6e-05 24.3 0.2 0.00035 21.1 0.2 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain PS_Dcarbxylase PF02666.15 EGC38394.1 - 0.19 11.2 0.2 0.19 11.2 0.2 1.8 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase FA_hydroxylase PF04116.13 EGC38396.1 - 8.7e-27 94.1 12.2 8.7e-27 94.1 12.2 1.7 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.13 EGC38397.1 - 5.8e-25 88.2 9.5 5.8e-25 88.2 9.5 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily Laminin_EGF PF00053.24 EGC38399.1 - 0.0059 16.7 2.0 0.0059 16.7 2.0 3.1 4 0 0 4 4 4 1 Laminin EGF domain PQQ_3 PF13570.6 EGC38399.1 - 0.012 16.1 2.7 3.4 8.3 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain EB PF01683.18 EGC38399.1 - 0.023 15.0 8.4 0.023 15.0 8.4 3.6 3 0 0 3 3 3 0 EB module RexA PF15969.5 EGC38399.1 - 0.024 14.2 0.1 0.046 13.3 0.1 1.4 1 0 0 1 1 1 0 Intracellular sensor of Lambda phage, Abi component cEGF PF12662.7 EGC38399.1 - 0.59 10.1 13.1 0.29 11.1 2.8 3.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like Arch_flagellin PF01917.16 EGC38399.1 - 0.65 10.2 6.5 0.16 12.2 2.3 2.0 2 1 0 2 2 2 0 Archaebacterial flagellin FNIP PF05725.12 EGC38400.1 - 4.3e-21 74.8 58.6 6e-08 32.7 0.3 10.2 8 2 1 9 9 9 6 FNIP Repeat Lactamase_B_2 PF12706.7 EGC38401.1 - 7.5e-36 123.5 0.0 1.1e-35 123.0 0.0 1.3 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGC38401.1 - 2.4e-14 53.6 0.0 3.2e-14 53.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGC38401.1 - 0.00046 20.2 0.0 0.0024 17.9 0.0 2.0 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily FNIP PF05725.12 EGC38402.1 - 2.6e-56 187.5 22.4 2.3e-11 43.7 1.3 6.8 4 1 3 7 7 7 7 FNIP Repeat DUF1769 PF08588.10 EGC38402.1 - 0.17 12.1 1.3 30 4.9 0.0 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1769) zf-RING_2 PF13639.6 EGC38403.1 - 1.1e-08 35.2 10.5 1.9e-08 34.5 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38403.1 - 1.8e-08 34.1 8.3 2.9e-08 33.4 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38403.1 - 4.6e-08 32.8 9.5 1.1e-07 31.7 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38403.1 - 3.2e-07 30.1 8.2 5.2e-07 29.4 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38403.1 - 8.2e-07 29.2 6.9 1.9e-06 28.1 6.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38403.1 - 0.00053 19.9 5.3 0.0012 18.8 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38403.1 - 0.012 15.6 10.3 0.023 14.7 10.3 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC38403.1 - 0.012 15.7 10.4 0.071 13.3 9.8 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGC38403.1 - 0.043 13.8 6.6 0.12 12.4 6.6 1.7 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.6 EGC38403.1 - 0.053 13.4 8.6 0.15 11.9 8.6 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC38403.1 - 0.32 11.2 4.0 0.8 9.9 4.0 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC38403.1 - 0.67 9.8 11.0 5.2 6.9 10.9 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC38403.1 - 5.2 6.8 8.7 9 6.0 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF4366 PF14283.6 EGC38405.1 - 0.46 10.5 1.9 3.7 7.6 0.7 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) Pneumo_att_G PF05539.11 EGC38405.1 - 7.5 6.0 14.6 11 5.5 14.6 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G ketoacyl-synt PF00109.26 EGC38406.1 - 2.4e-61 207.5 0.0 3.6e-61 206.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38406.1 - 4.4e-40 138.1 0.0 7.7e-40 137.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38406.1 - 4.4e-33 113.8 0.0 8.7e-33 112.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38406.1 - 2.3e-19 70.0 0.1 2.7e-16 60.0 0.0 2.9 2 1 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC38406.1 - 3.5e-19 69.1 0.0 5.8e-19 68.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC38406.1 - 3.7e-19 69.3 0.0 2.6e-18 66.6 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC38406.1 - 3.6e-15 56.4 0.4 2.3e-14 53.8 0.0 2.7 3 0 0 3 3 3 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N PF00107.26 EGC38406.1 - 9.3e-09 35.3 0.0 2.2e-08 34.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC38406.1 - 2.3e-08 35.2 0.0 7.2e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38406.1 - 2.6e-07 30.5 0.0 8e-07 28.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC38406.1 - 4.2e-07 29.9 0.0 1.7e-06 28.0 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38406.1 - 7.2e-07 29.1 0.2 5.4e-06 26.3 0.1 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC38406.1 - 7.3e-06 26.5 0.0 3.5e-05 24.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC38406.1 - 1.5e-05 25.3 0.0 3.7e-05 24.0 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC38406.1 - 0.0095 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 EGC38406.1 - 0.029 14.0 0.0 0.1 12.2 0.0 2.0 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase SAT PF16073.5 EGC38406.1 - 0.029 14.1 0.1 0.24 11.1 0.0 2.4 3 0 0 3 3 3 0 Starter unit:ACP transacylase in aflatoxin biosynthesis DNA_repr_REX1B PF14966.6 EGC38406.1 - 0.3 11.8 3.2 1.9 9.2 3.2 2.6 1 0 0 1 1 1 0 DNA repair REX1-B FNIP PF05725.12 EGC38407.1 - 2.8e-42 142.6 88.3 2e-11 43.9 7.4 12.2 9 2 3 12 12 12 11 FNIP Repeat DDE_Tnp_4 PF13359.6 EGC38408.1 - 1.6e-20 73.3 0.1 3.2e-20 72.4 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF963 PF06131.11 EGC38408.1 - 0.0075 15.7 3.1 0.0075 15.7 3.1 2.1 2 1 0 2 2 2 1 Schizosaccharomyces pombe repeat of unknown function (DUF963) CHORD PF04968.12 EGC38410.1 - 6.1e-48 161.4 29.8 3.4e-24 85.3 9.0 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.16 EGC38410.1 - 8.1e-11 42.8 1.6 1.9e-10 41.6 1.6 1.6 1 0 0 1 1 1 1 CS domain Secretin_N_2 PF07655.13 EGC38411.1 - 0.0018 18.8 14.0 0.0056 17.2 14.0 1.9 1 0 0 1 1 1 1 Secretin N-terminal domain Apc15p PF05841.11 EGC38411.1 - 1.6 9.6 13.9 4 8.3 13.9 1.6 1 0 0 1 1 1 0 Apc15p protein Menin PF05053.13 EGC38411.1 - 4.2 5.6 9.6 7 4.9 9.6 1.2 1 0 0 1 1 1 0 Menin Phytochelatin PF05023.14 EGC38412.1 - 1.7e-90 301.9 0.0 2.8e-90 301.2 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.6 EGC38412.1 - 0.00035 21.1 1.9 0.53 10.8 0.0 3.5 3 0 0 3 3 3 2 Peptidase_C39 like family Phytochelatin_C PF09328.10 EGC38412.1 - 0.00075 18.9 0.0 0.025 13.9 0.0 2.7 3 0 0 3 3 3 1 Domain of unknown function (DUF1984) Peptidase_C39 PF03412.15 EGC38412.1 - 0.013 15.3 0.0 5.3 6.8 0.0 2.6 2 0 0 2 2 2 0 Peptidase C39 family FNIP PF05725.12 EGC38413.1 - 1.3e-94 310.1 81.1 1e-11 44.8 0.5 13.3 9 1 5 15 15 15 14 FNIP Repeat DUF1769 PF08588.10 EGC38413.1 - 8.5e-06 25.9 12.5 0.57 10.4 0.3 7.2 4 3 2 6 6 6 3 Protein of unknown function (DUF1769) LRR_5 PF13306.6 EGC38413.1 - 3.6e-05 23.7 17.6 0.1 12.6 0.1 5.4 2 1 3 6 6 6 4 BspA type Leucine rich repeat region (6 copies) DUF840 PF05801.11 EGC38413.1 - 0.24 11.5 2.5 1.9 8.6 0.0 3.3 3 0 0 3 3 3 0 Lagovirus protein of unknown function (DUF840) SMC_N PF02463.19 EGC38414.1 - 2.8e-26 92.3 2.8 5.6e-25 88.1 2.8 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.6 EGC38414.1 - 7.2e-08 33.2 51.9 7.2e-08 33.2 51.9 6.3 3 2 1 4 4 4 1 AAA domain AAA_15 PF13175.6 EGC38414.1 - 1.7e-05 24.7 29.2 1.7e-05 24.7 29.2 4.5 2 1 1 3 3 3 1 AAA ATPase domain AAA_29 PF13555.6 EGC38414.1 - 7.9e-05 22.3 0.0 0.00016 21.3 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC38414.1 - 0.00055 19.8 0.8 0.00055 19.8 0.8 4.1 4 0 0 4 4 4 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EGC38414.1 - 0.024 14.2 0.0 0.024 14.2 0.0 4.9 6 2 1 7 7 7 0 AAA domain ABC_tran PF00005.27 EGC38414.1 - 0.27 11.7 0.0 0.27 11.7 0.0 5.6 3 2 1 4 4 4 0 ABC transporter OAD_gamma PF04277.13 EGC38415.1 - 0.037 14.6 0.0 0.16 12.6 0.0 2.1 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain COX2_TM PF02790.15 EGC38415.1 - 0.15 12.2 0.6 0.44 10.7 0.6 1.7 1 0 0 1 1 1 0 Cytochrome C oxidase subunit II, transmembrane domain WBP-1 PF11669.8 EGC38415.1 - 0.26 11.9 0.1 0.26 11.9 0.1 4.7 2 2 1 3 3 3 0 WW domain-binding protein 1 DUF2973 PF11189.8 EGC38415.1 - 1.4 9.1 3.5 1.5 9.0 0.5 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) OppC_N PF12911.7 EGC38415.1 - 7.3 6.7 7.0 32 4.6 7.0 2.3 1 1 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Aminotran_5 PF00266.19 EGC38418.1 - 0.11 11.4 0.0 0.13 11.2 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V zf-C3HC4_3 PF13920.6 EGC38419.1 - 4.1e-09 36.2 7.8 6.7e-09 35.5 7.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38419.1 - 1.2e-08 35.1 10.5 2e-08 34.4 10.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC38419.1 - 5.1e-08 32.7 9.5 1.1e-07 31.6 9.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38419.1 - 3.2e-07 30.1 8.2 5.4e-07 29.3 8.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38419.1 - 8.4e-07 29.2 6.9 2e-06 28.0 6.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38419.1 - 0.00058 19.8 5.3 0.0012 18.8 5.3 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38419.1 - 0.0043 17.0 9.6 0.008 16.1 9.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC38419.1 - 0.0093 16.1 10.0 0.056 13.6 9.4 2.3 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC38419.1 - 0.031 14.1 7.9 0.087 12.7 7.9 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.7 EGC38419.1 - 0.055 13.5 7.0 0.18 11.9 7.1 1.8 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_10 PF16685.5 EGC38419.1 - 0.32 11.2 3.7 0.61 10.3 3.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC38419.1 - 0.42 10.7 5.0 0.9 9.6 5.0 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC38419.1 - 0.63 9.9 11.1 4.5 7.2 11.0 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain HCO3_cotransp PF00955.21 EGC38419.1 - 1.3 7.7 5.1 2.5 6.8 5.1 1.4 1 0 0 1 1 1 0 HCO3- transporter family Zn_ribbon_17 PF17120.5 EGC38419.1 - 2.8 7.6 7.7 4.8 6.9 7.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type FNIP PF05725.12 EGC38420.1 - 8.4e-85 278.7 63.6 1.3e-13 50.9 3.7 10.2 7 3 3 11 11 11 10 FNIP Repeat LRR_5 PF13306.6 EGC38420.1 - 6.4e-08 32.6 4.0 0.24 11.4 0.0 4.3 1 1 1 3 3 3 3 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC38420.1 - 0.055 13.7 11.7 19 5.6 0.0 7.1 6 1 4 10 10 10 0 Protein of unknown function (DUF1769) FA_hydroxylase PF04116.13 EGC38421.1 - 4.1e-25 88.7 13.6 4.1e-25 88.7 13.6 1.6 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FNIP PF05725.12 EGC38422.1 - 9.5e-74 243.4 30.3 1.5e-14 53.9 0.2 8.0 3 1 4 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 EGC38422.1 - 6.4e-06 26.3 8.1 5.7 7.2 0.0 7.6 6 2 3 9 9 9 4 Protein of unknown function (DUF1769) Pkinase_Tyr PF07714.17 EGC38423.1 - 5e-34 117.7 0.0 6.7e-34 117.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC38423.1 - 1.5e-27 96.6 0.0 2.1e-27 96.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Fe_hyd_SSU PF02256.17 EGC38424.1 - 0.068 13.3 0.2 0.18 11.9 0.2 1.7 1 0 0 1 1 1 0 Iron hydrogenase small subunit Pex2_Pex12 PF04757.14 EGC38424.1 - 0.41 10.2 4.2 0.13 11.9 0.9 1.9 2 0 0 2 2 2 0 Pex2 / Pex12 amino terminal region DUF2465 PF10239.9 EGC38424.1 - 0.71 9.1 7.9 0.24 10.6 5.2 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2465) DDHD PF02862.17 EGC38425.1 - 0.11 12.6 2.9 0.13 12.4 2.9 1.0 1 0 0 1 1 1 0 DDHD domain Connexin PF00029.19 EGC38425.1 - 0.21 11.3 4.0 0.2 11.4 4.0 1.2 1 0 0 1 1 1 0 Connexin ArlS_N PF18719.1 EGC38425.1 - 0.25 11.5 7.5 0.3 11.3 7.5 1.0 1 0 0 1 1 1 0 ArlS sensor domain Pinin_SDK_memA PF04696.13 EGC38425.1 - 0.35 10.9 20.3 0.21 11.7 13.3 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region CDPS PF16715.5 EGC38425.1 - 0.39 10.3 3.6 0.47 10.1 3.6 1.0 1 0 0 1 1 1 0 Cyclodipeptide synthase Trypan_glycop PF00913.19 EGC38425.1 - 0.48 9.6 5.9 0.58 9.4 5.9 1.0 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) DUF4337 PF14235.6 EGC38425.1 - 0.96 9.5 9.5 1.2 9.2 9.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) V_ATPase_I PF01496.19 EGC38425.1 - 0.99 7.2 7.2 1.1 7.0 7.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Presenilin PF01080.17 EGC38425.1 - 2.2 7.0 3.4 2 7.1 3.4 1.1 1 0 0 1 1 1 0 Presenilin Atrophin-1 PF03154.15 EGC38425.1 - 8.8 4.5 15.2 11 4.2 15.2 1.0 1 0 0 1 1 1 0 Atrophin-1 family Caldesmon PF02029.15 EGC38425.1 - 8.9 4.9 22.0 10 4.7 22.0 1.1 1 0 0 1 1 1 0 Caldesmon DUF1764 PF08576.10 EGC38425.1 - 9.3 7.2 14.2 15 6.6 14.2 1.4 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) AAA_11 PF13086.6 EGC38425.1 - 9.6 5.9 11.6 11 5.7 11.6 1.1 1 0 0 1 1 1 0 AAA domain OTU PF02338.19 EGC38426.1 - 2e-11 44.5 0.0 2e-11 44.5 0.0 2.7 2 1 0 2 2 2 1 OTU-like cysteine protease ERM PF00769.19 EGC38426.1 - 0.0023 17.8 34.5 0.0029 17.4 34.5 1.1 1 0 0 1 1 1 1 Ezrin/radixin/moesin family V_ATPase_I PF01496.19 EGC38426.1 - 0.076 10.9 19.1 0.098 10.6 19.1 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CompInhib_SCIN PF11546.8 EGC38426.1 - 5.4 7.1 11.3 0.56 10.3 6.0 1.9 1 1 1 2 2 2 0 Staphylococcal complement inhibitor SCIN Helicase_C PF00271.31 EGC38427.1 - 0.002 18.5 0.3 0.56 10.6 0.0 3.0 2 1 1 3 3 3 2 Helicase conserved C-terminal domain DUF4451 PF14616.6 EGC38427.1 - 0.032 14.4 1.7 0.053 13.7 1.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4451) NVEALA PF14055.6 EGC38428.1 - 0.051 13.6 0.6 0.13 12.3 0.6 1.7 1 0 0 1 1 1 0 NVEALA protein EGF_2 PF07974.13 EGC38428.1 - 0.16 12.3 11.2 0.076 13.4 8.6 1.8 2 0 0 2 2 2 0 EGF-like domain EGF_Tenascin PF18720.1 EGC38428.1 - 2 8.6 6.1 5.6 7.1 6.1 1.8 1 0 0 1 1 1 0 Tenascin EGF domain DUF2482 PF10655.9 EGC38429.1 - 0.079 13.5 0.9 1.2 9.7 0.2 2.5 2 0 0 2 2 2 0 Hypothetical protein of unknown function (DUF2482) SH3_14 PF18343.1 EGC38429.1 - 0.11 12.5 1.6 2 8.5 0.1 2.6 2 1 0 2 2 2 0 Dda helicase SH3 domain Mito_carr PF00153.27 EGC38430.1 - 2.7e-64 213.1 4.3 6.3e-24 83.7 0.2 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-AN1 PF01428.16 EGC38431.1 - 1.2e-16 60.6 28.8 1.6e-10 41.0 9.7 2.7 3 0 0 3 3 3 2 AN1-like Zinc finger UBX PF00789.20 EGC38431.1 - 2.2e-06 27.8 0.0 6.2e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 UBX domain FA_desaturase PF00487.24 EGC38433.1 - 9.1e-29 101.0 25.8 2.6e-16 60.2 20.2 2.6 2 1 0 2 2 2 2 Fatty acid desaturase Cyt-b5 PF00173.28 EGC38433.1 - 2.1e-11 43.8 0.0 5.1e-11 42.6 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Dehydratase_hem PF13816.6 EGC38433.1 - 0.0037 16.7 0.0 0.0065 15.9 0.0 1.3 1 0 0 1 1 1 1 Haem-containing dehydratase RSN1_TM PF13967.6 EGC38433.1 - 4.2 7.1 13.9 0.58 9.9 2.8 3.7 3 1 0 3 3 3 0 Late exocytosis, associated with Golgi transport LPMO_10 PF03067.15 EGC38434.1 - 1.8e-31 110.3 0.1 2.1e-31 110.1 0.1 1.0 1 0 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading Ribosom_S12_S23 PF00164.25 EGC38435.1 - 1.8e-46 156.4 0.6 2.3e-46 156.1 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 DUF5305 PF17231.2 EGC38436.1 - 0.0044 16.4 1.1 0.11 11.8 0.1 2.7 2 1 1 3 3 3 1 Family of unknown function (DUF5305) Saf_2TM PF18303.1 EGC38436.1 - 0.0053 16.4 0.9 0.018 14.6 0.8 1.9 1 1 1 2 2 2 1 SAVED-fused 2TM effector domain HSP20 PF00011.21 EGC38438.1 - 4.6e-14 52.4 1.6 9.9e-07 28.9 0.0 2.2 1 1 1 2 2 2 2 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC38438.1 - 0.0047 16.4 0.5 0.12 11.9 0.1 2.6 2 1 1 3 3 3 1 HSP20-like domain found in ArsA CS PF04969.16 EGC38438.1 - 0.082 13.9 4.0 0.1 13.6 0.6 2.2 2 0 0 2 2 2 0 CS domain Opi1 PF08618.10 EGC38438.1 - 0.16 11.2 3.6 0.21 10.8 3.6 1.1 1 0 0 1 1 1 0 Transcription factor Opi1 BB_PF PF18063.1 EGC38439.1 - 5.8e-59 199.2 6.4 6.9e-59 198.9 6.4 1.1 1 0 0 1 1 1 1 Beta barrel Pore-forming domain Coiled PF05710.12 EGC38440.1 - 7.3e-23 81.2 20.8 8.2e-23 81.0 20.8 1.0 1 0 0 1 1 1 1 Coiled coil Coiled PF05710.12 EGC38441.1 - 5.4e-20 72.0 17.1 6e-20 71.9 17.1 1.0 1 0 0 1 1 1 1 Coiled coil Proteasom_Rpn13 PF04683.13 EGC38442.1 - 2.4e-21 76.0 0.0 4.8e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor RPN13_C PF16550.5 EGC38442.1 - 7e-18 64.8 0.1 1.1e-17 64.2 0.1 1.3 1 0 0 1 1 1 1 UCH-binding domain GET2 PF08690.10 EGC38442.1 - 0.059 13.0 4.6 0.084 12.5 4.6 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 Nucleo_P87 PF07267.11 EGC38442.1 - 0.95 8.2 5.7 1.1 8.0 5.7 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 MoaE PF02391.17 EGC38443.1 - 1.8e-33 115.2 0.0 2.1e-33 115.0 0.0 1.1 1 0 0 1 1 1 1 MoaE protein Cwf_Cwc_15 PF04889.12 EGC38444.1 - 1.6e-42 146.0 46.5 1.1e-41 143.2 46.5 1.8 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein MFAP1 PF06991.11 EGC38444.1 - 0.062 13.1 35.2 2.9 7.7 35.3 2.1 1 1 0 1 1 1 0 Microfibril-associated/Pre-mRNA processing Mpp10 PF04006.12 EGC38444.1 - 0.11 11.0 42.6 0.12 10.8 42.6 1.1 1 0 0 1 1 1 0 Mpp10 protein SAPS PF04499.15 EGC38444.1 - 0.68 8.6 20.5 0.82 8.4 20.5 1.3 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein BUD22 PF09073.10 EGC38444.1 - 7.4 5.8 43.9 10 5.3 43.9 1.1 1 0 0 1 1 1 0 BUD22 DSPc PF00782.20 EGC38445.1 - 1e-37 128.9 0.0 2.1e-37 127.9 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EGC38445.1 - 8.6e-06 26.2 0.2 0.00083 19.8 0.0 2.9 2 1 1 3 3 3 1 Rhodanese-like domain Y_phosphatase PF00102.27 EGC38445.1 - 0.00015 21.4 0.0 0.00026 20.6 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC38445.1 - 0.00061 19.9 0.0 0.0014 18.8 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1877 PF08974.10 EGC38445.1 - 0.076 13.1 0.0 0.14 12.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1877) Init_tRNA_PT PF04179.12 EGC38445.1 - 0.13 12.6 0.0 0.29 11.5 0.0 1.6 1 0 0 1 1 1 0 Rit1 DUSP-like domain DSPc PF00782.20 EGC38446.1 - 1.1e-34 119.1 0.6 2.6e-34 117.9 0.2 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.20 EGC38446.1 - 1.6e-08 35.0 0.3 9.9e-06 26.0 0.1 2.5 2 0 0 2 2 2 2 Rhodanese-like domain Y_phosphatase PF00102.27 EGC38446.1 - 0.0023 17.6 2.7 0.0051 16.4 0.0 2.4 2 1 1 3 3 3 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC38446.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.7 1 0 0 1 1 1 0 Inositol hexakisphosphate HORMA PF02301.18 EGC38447.1 - 3.7e-23 82.2 0.4 1e-22 80.8 0.4 1.6 1 1 0 1 1 1 1 HORMA domain bacHORMA_2 PF18173.1 EGC38447.1 - 0.00033 20.6 0.5 0.002 18.0 0.5 2.1 1 1 0 1 1 1 1 Bacterial HORMA domain 2 Hpr_kinase_N PF02603.16 EGC38447.1 - 0.0046 17.0 0.0 0.0081 16.2 0.0 1.5 1 0 0 1 1 1 1 HPr Serine kinase N terminus ATG101 PF07855.12 EGC38447.1 - 0.014 15.4 0.0 0.21 11.6 0.0 2.2 1 1 0 1 1 1 0 Autophagy-related protein 101 IMPa_N_2 PF18650.1 EGC38447.1 - 0.043 13.1 0.0 0.095 11.9 0.0 1.5 2 0 0 2 2 2 0 Immunomodulating metalloprotease N-terminal domain UbiA PF01040.18 EGC38448.1 - 2.3e-09 36.9 6.1 3.4e-09 36.4 6.1 1.3 1 1 0 1 1 1 1 UbiA prenyltransferase family Sigma_reg_N PF13800.6 EGC38448.1 - 3.4 8.0 9.7 17 5.7 0.0 3.2 2 1 0 2 2 2 0 Sigma factor regulator N-terminal F5_F8_type_C PF00754.25 EGC38449.1 - 3.9e-23 81.9 3.2 7.9e-23 81.0 3.2 1.5 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC38449.1 - 1.2e-21 76.7 0.4 3.6e-21 75.1 0.4 1.9 1 0 0 1 1 1 1 H-type lectin domain Flo11 PF10182.9 EGC38449.1 - 0.45 10.6 5.1 0.46 10.6 1.0 2.2 2 0 0 2 2 2 0 Flo11 domain Proteasome PF00227.26 EGC38450.1 - 3.6e-31 108.1 0.0 4.5e-31 107.8 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Rep_1B PF17873.1 EGC38450.1 - 0.16 11.9 0.7 0.25 11.2 0.1 1.7 2 0 0 2 2 2 0 Replicase polyprotein 1ab Fz PF01392.22 EGC38451.1 - 3.3e-06 27.7 1.1 4.5e-06 27.2 1.1 1.2 1 0 0 1 1 1 1 Fz domain PA14 PF07691.12 EGC38453.1 - 4.3e-15 55.8 0.1 7.5e-15 55.0 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.18 EGC38453.1 - 7.5e-06 25.7 4.7 7.5e-06 25.7 4.7 14.4 15 2 1 16 16 16 5 Dictyostelium (slime mold) repeat UBX PF00789.20 EGC38454.1 - 0.14 12.4 0.0 0.2 11.8 0.0 1.3 1 0 0 1 1 1 0 UBX domain p450 PF00067.22 EGC38455.1 - 3.3e-60 204.1 2.3 4.3e-60 203.8 2.3 1.2 1 0 0 1 1 1 1 Cytochrome P450 DUF1831 PF08866.10 EGC38455.1 - 0.1 13.1 3.2 0.1 13.0 0.8 2.3 2 0 0 2 2 2 0 Putative amino acid metabolism TFIID-31kDa PF02291.15 EGC38456.1 - 1.7e-47 160.5 0.0 1.9e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Bromo_TP PF07524.13 EGC38456.1 - 3.9e-05 23.6 0.0 5.6e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated CENP-S PF15630.6 EGC38456.1 - 9.3e-05 22.7 0.0 0.00012 22.3 0.0 1.2 1 0 0 1 1 1 1 CENP-S protein TFIID_30kDa PF03540.13 EGC38456.1 - 0.0055 16.6 0.0 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit CENP-T_C PF15511.6 EGC38456.1 - 0.0076 16.3 0.1 0.011 15.9 0.1 1.3 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold 2-oxoacid_dh PF00198.23 EGC38457.1 - 2.2e-70 236.7 0.0 4.6e-70 235.7 0.0 1.5 1 1 1 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.17 EGC38457.1 - 7.1e-09 35.9 0.0 1.8e-08 34.6 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Tubulin PF00091.25 EGC38458.1 - 6.8e-70 235.3 0.0 1.4e-69 234.2 0.0 1.6 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGC38458.1 - 2.9e-48 163.2 0.6 2.9e-48 163.2 0.6 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.9 EGC38458.1 - 6.3e-07 29.7 0.0 1.6e-06 28.4 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain Tubulin_2 PF13809.6 EGC38458.1 - 0.037 13.2 0.4 0.075 12.2 0.0 1.7 2 0 0 2 2 2 0 Tubulin like GST_C PF00043.25 EGC38459.1 - 9.8e-12 44.9 0.0 1.4e-11 44.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.20 EGC38459.1 - 5.1e-08 33.2 0.1 1e-07 32.2 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC38459.1 - 2.1e-07 31.2 0.0 4.4e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.6 EGC38459.1 - 9.8e-06 25.5 0.0 2.3e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC38459.1 - 1.8e-05 24.9 0.0 3.5e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.6 EGC38459.1 - 0.0015 18.8 0.0 0.0028 17.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_6 PF17171.4 EGC38459.1 - 0.14 12.0 0.0 0.32 10.8 0.0 1.6 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Tmemb_14 PF03647.13 EGC38460.1 - 4.5e-21 75.4 7.3 5.5e-21 75.1 7.3 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1774 PF08611.10 EGC38460.1 - 0.003 17.9 0.2 0.0049 17.1 0.0 1.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) Aim19 PF10315.9 EGC38460.1 - 0.005 17.1 2.3 0.0058 16.9 2.3 1.1 1 0 0 1 1 1 1 Altered inheritance of mitochondria protein 19 DUF2104 PF09877.9 EGC38460.1 - 0.15 12.4 3.2 0.18 12.1 0.9 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) Minor_capsid_1 PF10665.9 EGC38461.1 - 0.042 14.0 0.7 0.042 14.0 0.7 1.9 1 1 0 1 1 1 0 Minor capsid protein RVP PF00077.20 EGC38461.1 - 0.059 13.7 0.1 0.12 12.7 0.1 1.6 1 1 0 1 1 1 0 Retroviral aspartyl protease Oxysterol_BP PF01237.18 EGC38462.1 - 3.4e-33 115.0 12.7 8.3e-31 107.1 12.7 2.1 1 1 0 1 1 1 1 Oxysterol-binding protein DUF1481 PF07356.12 EGC38462.1 - 0.0052 16.6 0.8 0.0098 15.7 0.8 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1481) NQR2_RnfD_RnfE PF03116.15 EGC38463.1 - 0.065 12.6 1.1 0.077 12.4 1.1 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family MerC PF03203.14 EGC38463.1 - 0.098 13.1 0.1 0.12 12.8 0.1 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein RhoGEF PF00621.20 EGC38464.1 - 6e-52 176.5 3.5 6e-52 176.5 3.5 2.1 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC38464.1 - 2.5e-05 24.7 0.1 2.5e-05 24.7 0.1 2.7 2 1 0 2 2 2 1 PH domain Methyltransf_7 PF03492.15 EGC38465.1 - 9.1e-27 94.1 3.1 1.1e-26 93.8 3.1 1.1 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.12 EGC38465.1 - 0.078 13.6 0.0 0.43 11.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38465.1 - 0.12 13.1 0.0 8.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain COX6B PF02297.17 EGC38466.1 - 0.39 11.0 3.0 17 5.7 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIb B_lectin PF01453.24 EGC38467.1 - 1e-06 29.2 0.0 1.1e-05 25.9 0.0 2.1 1 1 1 2 2 2 1 D-mannose binding lectin DPPIV_N PF00930.21 EGC38467.1 - 0.0072 15.1 0.1 0.0081 15.0 0.1 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region PmoA PF14100.6 EGC38467.1 - 0.054 13.0 0.0 0.059 12.9 0.0 1.2 1 0 0 1 1 1 0 Methane oxygenase PmoA Coiled PF05710.12 EGC38468.1 - 8.1e-23 81.1 20.3 9.1e-23 80.9 20.3 1.0 1 0 0 1 1 1 1 Coiled coil Hydrolase_4 PF12146.8 EGC38469.1 - 2.8e-17 62.8 0.0 2.7e-12 46.5 0.0 2.5 1 1 1 2 2 2 2 Serine aminopeptidase, S33 Peptidase_S15 PF02129.18 EGC38469.1 - 1.8e-07 31.0 10.6 0.00043 20.0 0.1 3.3 2 1 1 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_1 PF00561.20 EGC38469.1 - 2.2e-07 30.8 0.1 2.2e-07 30.8 0.1 3.6 4 0 0 4 4 4 1 alpha/beta hydrolase fold Med3 PF11593.8 EGC38469.1 - 1.9e-05 24.1 19.6 1.9e-05 24.1 19.6 3.0 2 1 1 3 3 3 1 Mediator complex subunit 3 fungal FSH1 PF03959.13 EGC38469.1 - 0.00027 20.7 2.4 0.0004 20.1 0.0 2.3 2 1 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.12 EGC38469.1 - 0.012 14.4 0.0 0.048 12.3 0.0 1.9 1 1 1 2 2 2 0 Acetyl xylan esterase (AXE1) Trehalase_Ca-bi PF07492.11 EGC38469.1 - 0.015 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 Neutral trehalase Ca2+ binding domain GTA_holin_3TM PF11351.8 EGC38469.1 - 0.025 15.1 3.5 0.48 11.0 5.4 2.0 2 0 0 2 2 2 0 Holin of 3TMs, for gene-transfer release YqfD PF06898.11 EGC38469.1 - 0.053 12.4 3.5 0.077 11.8 3.5 1.2 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD Suf PF05843.14 EGC38469.1 - 7.8 6.4 30.4 0.39 10.7 16.5 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) G6PD_C PF02781.16 EGC38470.1 - 1.2e-115 385.7 0.0 1.6e-115 385.3 0.0 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.22 EGC38470.1 - 7.1e-56 189.6 0.1 1e-55 189.1 0.1 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Vpu PF00558.19 EGC38471.1 - 0.06 13.1 0.1 0.12 12.2 0.1 1.4 1 0 0 1 1 1 0 Vpu protein Ly49 PF08391.10 EGC38471.1 - 0.087 13.2 0.6 0.087 13.2 0.6 1.8 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Arf PF00025.21 EGC38472.1 - 6.7e-37 126.6 0.0 7.7e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.10 EGC38472.1 - 6.9e-11 41.9 0.0 1e-10 41.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC38472.1 - 1e-06 28.2 0.6 0.001 18.3 0.1 2.1 1 1 0 2 2 2 2 G-protein alpha subunit Roc PF08477.13 EGC38472.1 - 0.00015 22.0 0.1 0.007 16.6 0.1 2.2 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase AAA_14 PF13173.6 EGC38472.1 - 0.002 18.2 0.0 0.0032 17.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain Ras PF00071.22 EGC38472.1 - 0.0026 17.4 0.4 0.022 14.3 0.4 2.0 1 1 0 1 1 1 1 Ras family AAA_7 PF12775.7 EGC38472.1 - 0.0039 16.7 0.1 0.006 16.1 0.1 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region ABC_tran PF00005.27 EGC38472.1 - 0.0061 17.1 0.0 0.0078 16.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_23 PF13476.6 EGC38472.1 - 0.0076 16.8 0.1 0.011 16.3 0.1 1.5 1 1 0 1 1 1 1 AAA domain cobW PF02492.19 EGC38472.1 - 0.011 15.3 0.1 0.5 9.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGC38472.1 - 0.012 15.8 0.0 0.015 15.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGC38472.1 - 0.014 15.1 0.5 0.026 14.3 0.5 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation RsgA_GTPase PF03193.16 EGC38472.1 - 0.021 14.7 0.1 0.54 10.1 0.1 2.1 2 0 0 2 2 2 0 RsgA GTPase AAA_25 PF13481.6 EGC38472.1 - 0.025 14.2 0.0 0.029 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.23 EGC38472.1 - 0.026 14.6 0.1 0.11 12.6 0.1 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_29 PF13555.6 EGC38472.1 - 0.028 14.1 0.0 0.052 13.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain STAS PF01740.21 EGC38472.1 - 0.052 13.2 0.1 0.13 11.9 0.0 1.7 2 0 0 2 2 2 0 STAS domain AAA_24 PF13479.6 EGC38472.1 - 0.057 13.1 0.2 0.079 12.7 0.2 1.3 1 1 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGC38472.1 - 0.074 12.7 0.1 0.12 12.0 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.21 EGC38472.1 - 0.084 12.2 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC38472.1 - 0.099 12.6 0.1 0.21 11.6 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_30 PF13604.6 EGC38472.1 - 0.12 12.1 0.0 0.16 11.7 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC38472.1 - 0.12 12.6 0.1 0.16 12.3 0.1 1.4 1 1 0 1 1 1 0 AAA domain MeaB PF03308.16 EGC38472.1 - 0.14 11.1 0.1 0.6 9.0 0.0 1.8 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB AAA_28 PF13521.6 EGC38472.1 - 0.17 12.1 0.1 0.27 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.12 EGC38472.1 - 0.2 10.9 0.0 0.31 10.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin DUF655 PF04919.12 EGC38473.1 - 0.0007 19.6 0.0 0.003 17.5 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function (DUF655) ANAPC4_WD40 PF12894.7 EGC38473.1 - 0.031 14.6 0.0 0.16 12.3 0.0 2.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC38473.1 - 0.04 14.8 0.1 0.26 12.2 0.0 2.5 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-rbx1 PF12678.7 EGC38473.1 - 0.065 13.5 10.2 0.059 13.7 6.9 2.8 3 0 0 3 3 3 0 RING-H2 zinc finger domain zf-RING_2 PF13639.6 EGC38473.1 - 0.56 10.6 8.7 1.4 9.3 8.7 1.7 1 0 0 1 1 1 0 Ring finger domain Endonuclease_5 PF04493.14 EGC38474.1 - 2.8e-70 236.0 0.0 3.9e-70 235.6 0.0 1.1 1 0 0 1 1 1 1 Endonuclease V AMP-binding PF00501.28 EGC38475.1 - 7e-80 268.7 0.0 8.6e-80 268.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme GST_N_5 PF18485.1 EGC38475.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.8 2 0 0 2 2 2 0 Glutathione S-transferase, N-terminal domain AMP-binding PF00501.28 EGC38476.1 - 9.4e-80 268.3 0.0 1.1e-79 268.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.28 EGC38477.1 - 3.1e-85 286.3 0.0 3.8e-85 286.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC2_membrane PF01061.24 EGC38478.1 - 5.4e-37 127.3 17.5 8.7e-37 126.6 17.5 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC38478.1 - 2e-25 89.9 0.0 4.5e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC38478.1 - 0.00015 21.7 4.4 0.054 13.3 0.1 2.5 1 1 1 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system RsgA_GTPase PF03193.16 EGC38478.1 - 0.00029 20.8 1.3 0.00044 20.2 0.1 1.9 2 0 0 2 2 1 1 RsgA GTPase SMC_N PF02463.19 EGC38478.1 - 0.002 17.6 0.1 2.1 7.7 0.2 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain T2SSE PF00437.20 EGC38478.1 - 0.0084 15.2 0.1 0.015 14.4 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.6 EGC38478.1 - 0.01 15.5 0.5 0.024 14.4 0.5 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Invasin_D3 PF09134.10 EGC38478.1 - 0.023 15.0 0.0 0.063 13.6 0.0 1.6 2 0 0 2 2 1 0 Invasin, domain 3 AAA_30 PF13604.6 EGC38478.1 - 0.024 14.4 0.1 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGC38478.1 - 0.029 14.8 0.0 0.045 14.1 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_19 PF13245.6 EGC38478.1 - 0.042 14.2 0.1 0.11 12.8 0.1 1.7 2 0 0 2 2 2 0 AAA domain NACHT PF05729.12 EGC38478.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.19 EGC38478.1 - 0.093 12.3 0.2 0.18 11.4 0.2 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain MMR_HSR1 PF01926.23 EGC38478.1 - 0.11 12.6 0.2 0.28 11.3 0.2 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_23 PF13476.6 EGC38478.1 - 0.12 12.8 4.6 0.077 13.5 1.6 2.0 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.20 EGC38478.1 - 0.15 11.2 1.8 0.48 9.5 1.7 1.8 1 1 1 2 2 2 0 G-protein alpha subunit NTPase_1 PF03266.15 EGC38478.1 - 0.16 11.9 1.9 0.34 10.8 0.4 2.0 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.9 EGC38478.1 - 0.19 10.5 0.2 0.29 9.9 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class AAA_28 PF13521.6 EGC38478.1 - 0.22 11.7 0.9 0.4 10.9 0.9 1.4 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC38478.1 - 0.31 11.3 2.3 0.63 10.3 0.3 2.4 2 1 1 3 3 3 0 AAA domain ABC2_membrane_3 PF12698.7 EGC38478.1 - 0.51 9.4 22.9 0.044 12.9 17.7 1.9 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF2569 PF10754.9 EGC38478.1 - 0.52 10.8 5.3 1.5 9.3 4.9 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2569) Orf78 PF06024.12 EGC38480.1 - 0.052 13.9 4.3 0.062 13.6 4.3 1.2 1 0 0 1 1 1 0 Orf78 (ac78) Pex2_Pex12 PF04757.14 EGC38480.1 - 0.067 12.8 3.5 0.073 12.6 3.5 1.1 1 0 0 1 1 1 0 Pex2 / Pex12 amino terminal region RICTOR_N PF14664.6 EGC38480.1 - 0.13 11.2 1.5 0.15 11.0 1.5 1.0 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term Peroxin-13_N PF04088.13 EGC38480.1 - 0.31 11.3 1.9 0.36 11.1 1.9 1.1 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Folate_carrier PF01770.18 EGC38480.1 - 0.63 8.7 2.1 0.67 8.6 2.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Secretin_N_2 PF07655.13 EGC38480.1 - 0.88 10.2 14.7 1.2 9.7 14.7 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain DUF4271 PF14093.6 EGC38480.1 - 3.4 7.5 6.1 0.55 10.1 1.8 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4271) Menin PF05053.13 EGC38480.1 - 8.5 4.6 9.5 9.9 4.4 9.5 1.0 1 0 0 1 1 1 0 Menin ORC4_C PF14629.6 EGC38481.1 - 2.4e-19 69.6 0.1 3.5e-19 69.1 0.1 1.2 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus AAA PF00004.29 EGC38481.1 - 1.1e-06 29.1 0.7 2.8e-06 27.8 0.2 1.9 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ATPase_2 PF01637.18 EGC38481.1 - 1.6e-06 28.2 3.2 1.6e-06 28.2 3.2 1.6 2 0 0 2 2 2 1 ATPase domain predominantly from Archaea AAA_16 PF13191.6 EGC38481.1 - 1e-05 26.0 0.0 3.5e-05 24.2 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.6 EGC38481.1 - 3.1e-05 24.0 0.6 0.00012 22.1 0.1 2.4 2 1 0 2 2 2 1 AAA domain DUF815 PF05673.13 EGC38481.1 - 0.0004 19.6 0.0 0.00071 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_22 PF13401.6 EGC38481.1 - 0.00067 19.9 0.0 0.002 18.4 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGC38481.1 - 0.0022 17.6 0.0 0.005 16.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TniB PF05621.11 EGC38481.1 - 0.0029 17.0 0.1 0.063 12.7 0.1 2.2 1 1 0 1 1 1 1 Bacterial TniB protein T2SSE PF00437.20 EGC38481.1 - 0.032 13.3 0.0 0.054 12.5 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Cdc6_C PF09079.11 EGC38481.1 - 0.041 13.9 0.1 0.11 12.5 0.1 1.8 2 0 0 2 2 1 0 CDC6, C terminal winged helix domain NACHT PF05729.12 EGC38481.1 - 0.046 13.6 0.0 0.91 9.4 0.0 2.4 2 1 0 2 2 2 0 NACHT domain PEP-utilizers PF00391.23 EGC38481.1 - 0.17 11.6 0.0 0.37 10.5 0.0 1.5 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain TetR_C_19 PF17924.1 EGC38481.1 - 0.47 11.0 4.9 0.85 10.2 0.4 3.0 3 0 0 3 3 3 0 Tetracyclin repressor-like, C-terminal domain Rpr2 PF04032.16 EGC38482.1 - 0.011 16.0 1.6 0.043 14.1 1.3 2.2 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain ATF7IP_BD PF16788.5 EGC38482.1 - 0.043 13.9 4.7 0.053 13.6 4.5 1.3 1 1 0 1 1 1 0 ATF-interacting protein binding domain Amino_oxidase PF01593.24 EGC38483.1 - 8.1e-56 190.2 0.0 9.3e-56 190.0 0.0 1.0 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.6 EGC38483.1 - 7.3e-11 42.1 0.0 1.5e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.6 EGC38483.1 - 3.2e-06 26.6 1.0 0.00087 18.6 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.22 EGC38483.1 - 3.4e-05 23.1 0.5 0.0043 16.2 0.0 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.24 EGC38483.1 - 0.00036 19.7 0.0 0.00049 19.3 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.24 EGC38483.1 - 0.00067 19.3 0.1 0.0031 17.2 0.0 1.9 2 0 0 2 2 2 1 FAD dependent oxidoreductase Thi4 PF01946.17 EGC38483.1 - 0.0017 17.6 0.0 0.0072 15.6 0.0 2.0 3 0 0 3 3 3 1 Thi4 family HI0933_like PF03486.14 EGC38483.1 - 0.0043 15.8 0.0 0.019 13.7 0.0 1.9 2 0 0 2 2 2 1 HI0933-like protein FAD_oxidored PF12831.7 EGC38483.1 - 0.009 15.4 0.0 0.014 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.14 EGC38483.1 - 0.012 14.9 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC38483.1 - 0.064 13.8 0.1 0.3 11.7 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.19 EGC38483.1 - 0.22 10.8 0.0 0.31 10.2 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FUSC_2 PF13515.6 EGC38484.1 - 2.3e-15 56.8 32.9 6.9e-14 52.1 13.6 2.5 2 0 0 2 2 2 2 Fusaric acid resistance protein-like Vpu PF00558.19 EGC38484.1 - 0.21 11.4 4.9 0.073 12.8 0.4 2.6 2 0 0 2 2 2 0 Vpu protein adh_short PF00106.25 EGC38485.1 - 4.4e-07 29.6 0.0 7.6e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC38485.1 - 0.0053 16.3 0.0 0.0084 15.7 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC38485.1 - 0.2 11.5 0.0 0.34 10.8 0.0 1.3 1 0 0 1 1 1 0 KR domain Nucleoporin_FG PF13634.6 EGC38486.1 - 1e-31 109.6 232.0 9.7e-12 45.6 29.7 7.9 1 1 7 9 9 9 9 Nucleoporin FG repeat region Nsp1_C PF05064.13 EGC38486.1 - 7.8e-16 57.9 8.7 7.8e-16 57.9 8.7 2.4 1 1 1 2 2 2 1 Nsp1-like C-terminal region DUF45 PF01863.17 EGC38486.1 - 1.6 8.7 6.7 0.68 9.9 4.5 1.4 2 0 0 2 2 2 0 Protein of unknown function DUF45 CcdA PF07362.12 EGC38486.1 - 2.4 8.7 4.4 9.5 6.7 0.5 2.5 2 0 0 2 2 2 0 Post-segregation antitoxin CcdA Cauli_AT PF03233.13 EGC38486.1 - 2.5 8.0 12.9 1.5 8.7 7.2 2.4 2 0 0 2 2 2 0 Aphid transmission protein Tropomyosin_1 PF12718.7 EGC38486.1 - 9.7 6.3 14.6 2.9 8.0 8.9 2.0 1 1 1 2 2 2 0 Tropomyosin like DIOX_N PF14226.6 EGC38487.1 - 3.1e-26 92.4 0.2 8.6e-26 91.0 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC38487.1 - 8.4e-17 61.5 0.0 1.5e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3377 PF11857.8 EGC38488.1 - 0.0081 16.1 0.5 0.022 14.7 0.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) ECF_trnsprt PF12822.7 EGC38488.1 - 2.7 8.1 9.7 0.18 11.9 2.0 2.3 2 0 0 2 2 2 0 ECF transporter, substrate-specific component DnaJ PF00226.31 EGC38489.1 - 0.00059 19.9 0.1 0.00059 19.9 0.1 3.3 3 0 0 3 3 3 1 DnaJ domain Spc7 PF08317.11 EGC38489.1 - 0.0078 15.1 12.9 0.0078 15.1 12.9 2.5 1 1 0 2 2 2 1 Spc7 kinetochore protein BCAS2 PF05700.11 EGC38489.1 - 0.013 15.2 10.7 0.013 15.2 10.7 2.6 1 1 1 2 2 2 0 Breast carcinoma amplified sequence 2 (BCAS2) DUF948 PF06103.11 EGC38489.1 - 1.4 9.2 7.9 1.3 9.3 2.8 3.0 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) DUF2325 PF10087.9 EGC38489.1 - 2.8 8.1 6.2 1.7 8.8 0.2 3.0 3 1 0 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2325) RET_CLD3 PF17812.1 EGC38490.1 - 0.0026 18.0 0.1 0.0036 17.5 0.1 1.1 1 0 0 1 1 1 1 RET Cadherin like domain 3 DNTTIP1_dimer PF18192.1 EGC38491.1 - 3.5 8.0 5.6 1.4 9.3 0.4 2.7 3 0 0 3 3 3 0 DNTTIP1 dimerisation domain Mpv17_PMP22 PF04117.12 EGC38494.1 - 1.2e-22 79.9 0.2 2.4e-22 78.9 0.2 1.6 1 0 0 1 1 1 1 Mpv17 / PMP22 family UQ_con PF00179.26 EGC38495.1 - 3.8e-24 84.9 0.0 1.4e-23 83.1 0.0 2.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.13 EGC38495.1 - 0.00072 19.4 0.3 0.0029 17.4 0.1 2.1 2 0 0 2 2 2 1 UEV domain Big_4 PF07532.11 EGC38495.1 - 0.22 11.3 1.1 0.45 10.3 0.1 2.1 2 0 0 2 2 2 0 Bacterial Ig-like domain (group 4) ketoacyl-synt PF00109.26 EGC38496.1 - 1.6e-36 126.2 0.0 3.2e-36 125.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC38496.1 - 9.7e-33 112.7 0.0 2e-32 111.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Acyl_transf_1 PF00698.21 EGC38496.1 - 1.2e-32 113.8 0.0 5.8e-26 91.8 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain KR PF08659.10 EGC38496.1 - 7.7e-28 97.6 0.1 3.8e-27 95.4 0.0 2.1 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EGC38496.1 - 7.8e-19 68.3 2.9 1e-18 67.9 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain PS-DH PF14765.6 EGC38496.1 - 3.2e-18 66.0 0.0 5.1e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38496.1 - 2e-15 57.2 1.8 7.5e-15 55.4 0.0 2.8 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38496.1 - 2.2e-10 41.7 0.0 8.4e-10 39.8 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGC38496.1 - 9e-10 38.6 0.0 2.1e-09 37.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38496.1 - 6.4e-08 32.4 0.0 1.8e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.6 EGC38496.1 - 3.4e-07 30.2 0.3 2.4e-06 27.4 0.1 2.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC38496.1 - 8.3e-07 29.6 0.0 7e-06 26.6 0.0 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38496.1 - 1.4e-06 28.2 0.0 7.1e-06 26.0 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGC38496.1 - 2.6e-06 27.7 0.1 6.5e-06 26.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EGC38496.1 - 0.0057 16.1 0.2 0.02 14.3 0.1 2.0 2 0 0 2 2 2 1 short chain dehydrogenase DUF4373 PF14297.6 EGC38496.1 - 0.017 15.9 0.0 0.33 11.8 0.0 3.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4373) Thiolase_N PF00108.23 EGC38496.1 - 0.024 14.0 0.0 0.048 13.0 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_28 PF02636.17 EGC38496.1 - 0.037 13.7 0.0 0.16 11.6 0.0 2.1 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase ketoacyl-synt PF00109.26 EGC38497.1 - 1.3e-60 205.1 0.0 2e-60 204.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38497.1 - 5.3e-43 147.7 0.0 8.9e-43 147.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38497.1 - 9.2e-33 112.8 0.0 2e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38497.1 - 9.3e-28 97.4 0.1 4.4e-27 95.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EGC38497.1 - 4.4e-19 69.1 0.0 4.4e-19 69.1 0.0 3.3 4 0 0 4 4 2 1 Methyltransferase domain PS-DH PF14765.6 EGC38497.1 - 4.1e-18 65.6 0.0 6.4e-18 65.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38497.1 - 3.5e-15 56.4 0.1 2.3e-14 53.8 0.0 2.6 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38497.1 - 1.3e-10 42.5 0.0 4.3e-10 40.7 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGC38497.1 - 7.7e-10 38.8 0.0 1.9e-09 37.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EGC38497.1 - 1.1e-08 35.0 0.3 7.6e-08 32.3 0.1 2.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38497.1 - 9.3e-08 32.1 0.0 5.1e-07 29.7 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EGC38497.1 - 1.4e-07 31.4 0.1 4e-07 29.9 0.1 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC38497.1 - 4e-07 30.6 0.0 3.5e-06 27.6 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38497.1 - 1e-06 29.3 0.0 1.3e-05 25.8 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.25 EGC38497.1 - 8.6e-06 26.0 0.1 2e-05 24.8 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF4373 PF14297.6 EGC38497.1 - 0.0095 16.7 0.2 0.17 12.7 0.0 3.4 2 0 0 2 2 1 1 Domain of unknown function (DUF4373) Thiolase_N PF00108.23 EGC38497.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain SAT PF16073.5 EGC38497.1 - 0.071 12.8 0.0 0.44 10.2 0.0 2.2 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis ketoacyl-synt PF00109.26 EGC38498.1 - 4.3e-60 203.4 0.0 6.2e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38498.1 - 1.6e-42 146.2 0.0 2.7e-42 145.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38498.1 - 7e-33 113.1 0.0 1.5e-32 112.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38498.1 - 1.8e-26 93.1 0.0 8.8e-26 90.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EGC38498.1 - 2e-19 70.2 2.9 2.5e-19 69.8 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain PS-DH PF14765.6 EGC38498.1 - 2.1e-18 66.6 0.0 3.3e-18 66.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38498.1 - 2.1e-15 57.1 0.0 1e-14 54.9 0.0 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38498.1 - 2.1e-10 41.7 0.0 6.7e-10 40.1 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGC38498.1 - 6.5e-10 39.1 0.0 1.5e-09 37.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_31 PF13847.6 EGC38498.1 - 1.5e-08 34.6 0.2 1.2e-07 31.6 0.1 2.8 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.12 EGC38498.1 - 3.2e-08 33.4 0.0 9.3e-08 31.9 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC38498.1 - 9.6e-08 32.0 0.0 3.4e-07 30.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38498.1 - 1.5e-06 28.8 0.0 1.1e-05 26.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC38498.1 - 1.8e-06 28.5 0.0 7.2e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC38498.1 - 4.7e-06 26.9 0.2 1.2e-05 25.6 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site SAT PF16073.5 EGC38498.1 - 0.067 12.9 0.0 0.23 11.2 0.0 1.9 2 0 0 2 2 1 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Thiolase_N PF00108.23 EGC38498.1 - 0.19 11.1 0.0 0.46 9.8 0.0 1.6 1 0 0 1 1 1 0 Thiolase, N-terminal domain HA2 PF04408.23 EGC38499.1 - 5.2e-13 49.2 0.0 1e-12 48.3 0.0 1.6 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC38499.1 - 2.9e-10 40.3 0.1 4.7e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold RnlB_antitoxin PF15933.5 EGC38499.1 - 0.0058 16.9 0.2 0.013 15.8 0.2 1.6 1 0 0 1 1 1 1 Antitoxin to bacterial toxin RNase LS or RnlA CMAS PF02353.20 EGC38501.1 - 1.9e-70 237.3 2.6 2.2e-70 237.1 2.0 1.4 1 1 1 2 2 2 1 Mycolic acid cyclopropane synthetase Methyltransf_25 PF13649.6 EGC38501.1 - 4e-11 43.5 0.0 7.7e-11 42.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38501.1 - 1.5e-10 41.1 0.0 2.5e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC38501.1 - 1.2e-08 35.5 0.0 2.8e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC38501.1 - 1.5e-08 35.3 0.0 2.8e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38501.1 - 1.1e-07 31.8 0.1 2.3e-07 30.7 0.1 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGC38501.1 - 2.2e-05 24.4 0.0 4.1e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_4 PF02390.17 EGC38501.1 - 0.0014 18.1 0.2 0.0034 16.9 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Spermine_synth PF01564.17 EGC38501.1 - 0.0054 16.2 0.2 0.013 14.9 0.2 1.6 1 1 0 1 1 1 1 Spermine/spermidine synthase domain PCMT PF01135.19 EGC38501.1 - 0.016 14.9 0.0 0.029 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.12 EGC38501.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_18 PF12847.7 EGC38501.1 - 0.038 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.14 EGC38501.1 - 0.045 13.3 0.0 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain MetW PF07021.12 EGC38501.1 - 0.046 13.3 0.0 0.083 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.8 EGC38501.1 - 0.072 12.2 0.0 0.14 11.3 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase E1_UFD PF09358.10 EGC38501.1 - 0.13 13.0 0.7 0.54 11.0 0.3 2.2 2 0 0 2 2 2 0 Ubiquitin fold domain DUF2370 PF10176.9 EGC38502.1 - 0.097 12.3 1.3 0.62 9.7 1.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2370) MAPEG PF01124.18 EGC38502.1 - 6.2 6.7 6.5 1.2 9.0 3.2 1.5 2 0 0 2 2 2 0 MAPEG family LRR_2 PF07723.13 EGC38503.1 - 0.32 11.7 4.0 52 4.7 0.4 4.6 3 0 0 3 3 3 0 Leucine Rich Repeat DUF1279 PF06916.13 EGC38504.1 - 2.6e-22 79.2 1.4 3.7e-22 78.7 0.5 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1279) RNA_pol_Rpc4 PF05132.14 EGC38504.1 - 0.00092 19.7 0.9 0.0012 19.3 0.9 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Spore_coat_CotO PF14153.6 EGC38504.1 - 0.0046 16.9 5.4 0.0057 16.6 5.4 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Tim54 PF11711.8 EGC38504.1 - 0.0068 15.2 0.2 0.0076 15.1 0.2 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 PPP4R2 PF09184.11 EGC38504.1 - 0.0098 15.5 14.6 0.012 15.2 14.6 1.1 1 0 0 1 1 1 1 PPP4R2 RP-C_C PF11800.8 EGC38504.1 - 0.016 15.3 0.2 0.019 15.1 0.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region CSG2 PF16965.5 EGC38504.1 - 0.02 13.9 2.9 0.024 13.6 2.9 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Ureide_permease PF07168.11 EGC38504.1 - 0.021 13.6 0.2 0.025 13.3 0.2 1.1 1 0 0 1 1 1 0 Ureide permease Connexin PF00029.19 EGC38504.1 - 0.029 14.1 0.4 0.04 13.7 0.4 1.2 1 0 0 1 1 1 0 Connexin Zip PF02535.22 EGC38504.1 - 0.032 13.5 0.6 0.042 13.1 0.6 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter XRN_M PF17846.1 EGC38504.1 - 0.039 12.9 3.4 0.044 12.8 3.4 1.1 1 0 0 1 1 1 0 Xrn1 helical domain DDHD PF02862.17 EGC38504.1 - 0.041 14.0 5.3 0.052 13.7 5.3 1.1 1 0 0 1 1 1 0 DDHD domain CLN3 PF02487.17 EGC38504.1 - 0.065 12.3 1.4 0.083 11.9 1.4 1.2 1 0 0 1 1 1 0 CLN3 protein Cytomega_UL84 PF06284.11 EGC38504.1 - 0.091 11.2 1.3 0.1 11.0 1.3 1.2 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein PPL5 PF18168.1 EGC38504.1 - 0.092 12.0 5.6 0.13 11.6 5.6 1.2 1 0 0 1 1 1 0 Prim-pol family 5 DUF1682 PF07946.14 EGC38504.1 - 0.094 11.9 6.6 0.12 11.6 6.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pox_Ag35 PF03286.14 EGC38504.1 - 0.2 11.4 10.8 0.27 11.0 10.8 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CSRNP_N PF16019.5 EGC38504.1 - 0.49 10.3 5.8 0.66 9.8 5.8 1.1 1 0 0 1 1 1 0 Cysteine/serine-rich nuclear protein N-terminus DUF4820 PF16091.5 EGC38504.1 - 1.4 8.2 6.8 1.9 7.8 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) LMBR1 PF04791.16 EGC38504.1 - 1.6 7.5 6.2 2.6 6.8 6.2 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein ALMT PF11744.8 EGC38504.1 - 6.5 5.5 9.0 8.3 5.1 9.0 1.1 1 0 0 1 1 1 0 Aluminium activated malate transporter Sec7 PF01369.20 EGC38505.1 - 5.8e-40 136.9 2.6 1.5e-39 135.6 2.6 1.7 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.7 EGC38505.1 - 7e-28 97.5 9.8 7e-28 97.5 9.8 4.5 3 2 2 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Plasmod_dom_1 PF09715.10 EGC38505.1 - 4.3 7.5 7.5 18 5.4 0.4 4.2 4 0 0 4 4 4 0 Plasmodium protein of unknown function (Plasmod_dom_1) CAP_N PF01213.19 EGC38505.1 - 5 6.5 17.9 0.067 12.7 1.6 3.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) N terminal Ras PF00071.22 EGC38506.1 - 3.3e-55 186.1 1.9 3.7e-55 185.9 1.9 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38506.1 - 2.4e-32 111.7 0.8 4.2e-32 110.9 0.8 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38506.1 - 5.5e-13 48.7 0.2 6.8e-13 48.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC38506.1 - 3.4e-06 26.8 0.8 1.1e-05 25.1 0.6 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC38506.1 - 7.3e-06 26.0 0.2 1.1e-05 25.5 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC38506.1 - 0.00013 21.4 0.0 0.00018 21.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.12 EGC38506.1 - 0.00024 20.5 0.2 0.00027 20.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC38506.1 - 0.0019 18.2 0.1 1 9.3 0.0 2.2 1 1 0 2 2 2 2 RsgA GTPase G-alpha PF00503.20 EGC38506.1 - 0.011 15.0 0.6 2.3 7.3 0.2 2.3 1 1 1 2 2 2 0 G-protein alpha subunit FeoB_N PF02421.18 EGC38506.1 - 0.021 14.4 0.1 0.22 11.0 0.1 2.2 1 1 0 1 1 1 0 Ferrous iron transport protein B TniB PF05621.11 EGC38506.1 - 0.021 14.2 0.0 0.033 13.6 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein AAA_16 PF13191.6 EGC38506.1 - 0.027 14.9 0.0 0.045 14.1 0.0 1.4 1 1 0 1 1 1 0 AAA ATPase domain PduV-EutP PF10662.9 EGC38506.1 - 0.091 12.5 0.1 0.29 10.9 0.1 1.8 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Myb_DNA-binding PF00249.31 EGC38507.1 - 1.7e-19 69.7 2.3 1.9e-07 31.1 0.0 3.8 3 0 0 3 3 3 3 Myb-like DNA-binding domain EGF_2 PF07974.13 EGC38508.1 - 0.012 16.0 9.1 0.032 14.6 9.1 1.7 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGC38508.1 - 1.1 9.4 4.1 3.4 7.8 4.1 1.9 1 0 0 1 1 1 0 Tenascin EGF domain F-box_5 PF18511.1 EGC38509.1 - 0.36 10.4 1.6 1.1 8.9 0.6 2.2 2 0 0 2 2 2 0 F-box Methyltransf_12 PF08242.12 EGC38509.1 - 4 8.2 5.8 1.6 9.5 2.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain FNIP PF05725.12 EGC38510.1 - 1.9e-106 348.0 65.9 6.3e-16 58.3 1.6 10.4 9 1 3 12 12 12 11 FNIP Repeat DUF1769 PF08588.10 EGC38510.1 - 2.1e-09 37.5 7.5 3.5 7.9 0.1 9.7 10 2 1 11 11 11 3 Protein of unknown function (DUF1769) LRR_5 PF13306.6 EGC38510.1 - 6.7e-05 22.9 0.7 0.16 11.9 0.0 3.6 3 1 1 4 4 4 2 BspA type Leucine rich repeat region (6 copies) Ank_5 PF13857.6 EGC38511.1 - 5.6e-31 106.2 1.1 4.8e-09 36.3 0.1 5.9 3 2 2 5 5 5 5 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC38511.1 - 1.6e-29 102.3 6.1 6e-12 46.0 0.1 4.3 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC38511.1 - 4.3e-28 94.2 4.4 2e-05 24.6 0.0 7.5 8 0 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.6 EGC38511.1 - 6.7e-26 90.3 1.4 2.1e-08 34.5 0.0 6.0 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.30 EGC38511.1 - 9.2e-26 89.1 0.8 0.0028 18.0 0.0 6.9 7 0 0 7 7 7 5 Ankyrin repeat Cellulase PF00150.18 EGC38513.1 - 3.8e-05 23.3 0.5 0.00011 21.8 0.5 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ketoacyl-synt PF00109.26 EGC38514.1 - 2.9e-65 220.4 0.0 4.2e-65 219.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38514.1 - 1.9e-42 145.9 0.0 3.3e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38514.1 - 4.9e-32 110.4 0.0 1.1e-31 109.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38514.1 - 2.8e-28 99.0 0.1 1.4e-27 96.8 0.0 2.1 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.12 EGC38514.1 - 7.6e-20 71.5 0.0 7.6e-20 71.5 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain PS-DH PF14765.6 EGC38514.1 - 8.6e-18 64.6 0.0 1.3e-17 64.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38514.1 - 1.3e-12 48.2 0.6 9.5e-12 45.4 0.0 2.9 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGC38514.1 - 1.5e-10 41.2 0.0 5.8e-10 39.2 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC38514.1 - 3.9e-10 40.9 0.0 1.2e-09 39.3 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N PF00107.26 EGC38514.1 - 1.8e-09 37.6 0.0 4e-09 36.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38514.1 - 3.5e-07 30.1 0.0 1.1e-06 28.4 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC38514.1 - 2e-06 28.3 0.0 9e-06 26.3 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.25 EGC38514.1 - 0.00029 21.1 0.0 0.00095 19.5 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.6 EGC38514.1 - 0.00041 20.2 0.8 0.005 16.6 0.1 3.1 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.23 EGC38514.1 - 0.042 13.2 0.0 0.095 12.0 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain SAT PF16073.5 EGC38514.1 - 0.062 13.0 0.0 0.33 10.6 0.0 2.1 2 0 0 2 2 2 0 Starter unit:ACP transacylase in aflatoxin biosynthesis Cys_Met_Meta_PP PF01053.20 EGC38515.1 - 0.0034 16.0 0.1 0.0063 15.1 0.1 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGC38515.1 - 0.021 14.0 0.2 0.037 13.2 0.2 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II MIT_LIKE_ACTX PF17556.2 EGC38516.1 - 0.00017 22.1 11.5 0.00031 21.3 11.1 1.8 1 1 0 1 1 1 1 MIT-like atracotoxin family Prokineticin PF06607.11 EGC38516.1 - 0.0031 17.8 6.1 0.012 15.9 6.1 1.8 1 1 0 1 1 1 1 Prokineticin Nucleoside_tran PF01733.18 EGC38517.1 - 0.46 9.8 3.0 0.58 9.5 3.0 1.2 1 0 0 1 1 1 0 Nucleoside transporter LacI PF00356.21 EGC38517.1 - 0.83 9.5 0.0 0.83 9.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family RhoGEF PF00621.20 EGC38518.1 - 2.2e-36 125.8 10.1 2.2e-36 125.8 10.1 6.3 3 3 1 4 4 4 1 RhoGEF domain IQ PF00612.27 EGC38518.1 - 0.0007 19.2 0.1 0.0018 17.9 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.29 EGC38518.1 - 0.0029 18.1 0.2 0.0029 18.1 0.2 3.7 2 2 0 2 2 2 1 PH domain Med20 PF08612.11 EGC38520.1 - 2.9e-27 95.5 0.0 3.3e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF218 PF02698.17 EGC38521.1 - 1.4e-24 86.5 0.0 2.9e-24 85.5 0.0 1.5 1 0 0 1 1 1 1 DUF218 domain FtsH_ext PF06480.15 EGC38521.1 - 0.025 14.9 1.6 0.57 10.5 0.1 3.3 4 0 0 4 4 4 0 FtsH Extracellular Baculo_RING PF05883.11 EGC38521.1 - 0.068 13.2 0.7 1.8 8.5 0.0 2.5 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DUF1980 PF09323.10 EGC38521.1 - 0.62 9.9 7.5 0.11 12.3 3.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) CSG2 PF16965.5 EGC38521.1 - 0.63 8.9 3.5 1.3 7.9 3.5 1.5 1 0 0 1 1 1 0 Ceramide synthase regulator VIT PF08487.10 EGC38522.1 - 2e-27 95.6 0.1 5.1e-27 94.3 0.0 1.8 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGC38522.1 - 3.1e-26 92.2 0.0 1.2e-25 90.3 0.0 1.9 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.28 EGC38522.1 - 6.4e-10 39.5 0.0 2e-09 37.9 0.0 1.8 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC38522.1 - 1.7e-07 31.9 0.0 5.1e-07 30.3 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.6 EGC38522.1 - 0.00013 21.8 0.0 0.00038 20.3 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.9 EGC38522.1 - 0.084 13.0 0.0 0.16 12.0 0.0 1.4 1 0 0 1 1 1 0 vWA found in TerF C terminus DrsE PF02635.15 EGC38523.1 - 2.6e-07 31.0 0.0 3e-07 30.8 0.0 1.1 1 0 0 1 1 1 1 DsrE/DsrF-like family Homeodomain PF00046.29 EGC38524.1 - 8.3e-18 64.0 4.0 1.9e-17 62.9 4.0 1.6 1 0 0 1 1 1 1 Homeodomain Ank_2 PF12796.7 EGC38524.1 - 2.4e-06 28.0 0.0 6.7e-06 26.6 0.0 1.8 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC38524.1 - 3.5e-05 24.0 0.0 3.5e-05 24.0 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC38524.1 - 0.00013 22.2 0.0 0.00052 20.3 0.0 2.1 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.6 EGC38524.1 - 0.0029 18.1 0.0 0.0078 16.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC38524.1 - 0.013 15.9 0.0 0.2 12.3 0.0 2.8 2 0 0 2 2 2 0 Ankyrin repeat SR-25 PF10500.9 EGC38524.1 - 4.5 6.8 17.6 0.29 10.7 4.7 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein TetR_C_4 PF08359.11 EGC38525.1 - 0.1 12.7 2.7 0.21 11.7 0.2 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Ku_PK_bind PF08785.11 EGC38525.1 - 0.11 12.7 4.9 0.064 13.4 2.5 2.0 2 0 0 2 2 2 0 Ku C terminal domain like DUF1840 PF08895.11 EGC38525.1 - 0.54 10.6 3.6 1.8 9.0 2.6 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF1840) Syntaxin-6_N PF09177.11 EGC38525.1 - 1.8 9.2 10.6 0.14 12.7 2.4 2.7 1 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF2115 PF09888.9 EGC38525.1 - 6.1 7.3 11.1 0.52 10.8 2.8 2.4 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) NPR2 PF06218.11 EGC38526.1 - 1.3e-95 320.8 12.1 3.7e-81 273.2 10.4 2.7 1 1 1 2 2 2 2 Nitrogen permease regulator 2 NPR3 PF03666.13 EGC38526.1 - 3.3e-07 29.5 1.0 0.013 14.3 0.1 2.9 2 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.12 EGC38526.1 - 0.00046 20.7 1.6 0.0011 19.5 1.6 1.7 1 1 0 1 1 1 1 Docking domain of Afi1 for Arf3 in vesicle trafficking Calreticulin PF00262.18 EGC38528.1 - 2.5e-80 270.1 3.7 2.8e-80 269.9 3.7 1.0 1 0 0 1 1 1 1 Calreticulin family Laminin_G_3 PF13385.6 EGC38528.1 - 0.075 13.2 0.0 0.15 12.2 0.0 1.5 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily SID-1_RNA_chan PF13965.6 EGC38529.1 - 0.53 8.6 3.2 0.55 8.6 3.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 CLN3 PF02487.17 EGC38529.1 - 0.61 9.1 4.2 0.14 11.2 1.1 1.5 1 1 1 2 2 2 0 CLN3 protein ATP19 PF11022.8 EGC38529.1 - 0.83 10.1 3.4 7 7.1 3.4 2.3 1 1 0 1 1 1 0 ATP synthase subunit K NAP PF00956.18 EGC38530.1 - 1.7e-05 24.1 34.1 0.0011 18.2 22.0 2.4 1 1 1 2 2 2 2 Nucleosome assembly protein (NAP) RNA_pol_Rbc25 PF08292.12 EGC38530.1 - 0.023 15.0 3.8 0.023 15.0 3.8 2.2 2 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 PriA_C PF18074.1 EGC38530.1 - 0.26 12.1 2.6 0.24 12.2 0.8 1.8 2 0 0 2 2 2 0 Primosomal protein N C-terminal domain Psb28 PF03912.14 EGC38530.1 - 0.28 11.5 7.4 0.081 13.2 1.6 2.4 1 1 2 3 3 3 0 Psb28 protein Kelch_5 PF13854.6 EGC38531.1 - 5e-31 106.2 19.1 6.5e-07 29.2 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC38531.1 - 2e-30 104.6 8.5 6e-09 35.8 0.0 6.5 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC38531.1 - 1.9e-27 94.9 12.1 1.6e-06 28.2 0.0 8.3 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC38531.1 - 2.2e-25 88.0 17.6 1.3e-05 25.3 0.5 6.8 4 3 2 6 6 6 5 Kelch motif Kelch_1 PF01344.25 EGC38531.1 - 2.7e-25 87.7 19.5 2.9e-08 33.2 0.2 7.1 6 1 0 6 6 6 5 Kelch motif BTB PF00651.31 EGC38531.1 - 1.4e-24 86.5 0.6 2.6e-23 82.4 0.1 2.4 1 1 1 2 2 2 1 BTB/POZ domain Kelch_2 PF07646.15 EGC38531.1 - 6.3e-17 60.8 21.1 7.8e-05 22.5 0.1 7.6 7 1 0 7 7 7 4 Kelch motif BACK PF07707.15 EGC38531.1 - 0.021 14.9 0.3 2.1 8.5 0.0 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch CRA PF06589.11 EGC38533.1 - 0.024 14.7 5.8 0.024 14.7 5.8 2.0 2 1 0 2 2 2 0 Circumsporozoite-related antigen (CRA) MAP17 PF15807.5 EGC38533.1 - 0.061 13.6 4.0 0.17 12.1 0.0 2.3 2 0 0 2 2 2 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 DUF4787 PF16029.5 EGC38533.1 - 0.065 13.3 0.9 15 5.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4787) OATP PF03137.20 EGC38533.1 - 0.072 11.4 3.4 0.31 9.3 0.2 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family OSTbeta PF15048.6 EGC38533.1 - 0.16 12.1 0.1 0.16 12.1 0.1 1.9 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein Nucleoside_tran PF01733.18 EGC38533.1 - 0.18 11.2 1.9 0.14 11.5 0.4 1.5 2 0 0 2 2 2 0 Nucleoside transporter O-antigen_lig PF13425.6 EGC38533.1 - 0.8 8.4 17.2 0.1 11.4 8.9 2.0 2 0 0 2 2 2 0 O-antigen ligase like membrane protein Connexin PF00029.19 EGC38533.1 - 1.4 8.6 6.6 0.17 11.6 1.3 1.9 2 0 0 2 2 2 0 Connexin HCO3_cotransp PF00955.21 EGC38533.1 - 5.7 5.6 6.8 0.74 8.6 3.0 1.4 2 0 0 2 2 2 0 HCO3- transporter family Voltage_CLC PF00654.20 EGC38534.1 - 5.4e-98 328.5 20.4 5.4e-98 328.5 20.4 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGC38534.1 - 3.2e-11 43.5 0.1 0.00014 22.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain TAT_signal PF10518.9 EGC38534.1 - 0.00094 18.9 2.4 0.00094 18.9 2.4 2.5 2 0 0 2 2 2 1 TAT (twin-arginine translocation) pathway signal sequence UCR_Fe-S_N PF10399.9 EGC38534.1 - 0.0095 15.3 1.4 0.022 14.1 1.4 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal Corazonin PF17308.2 EGC38534.1 - 6 7.3 16.8 12 6.3 16.8 1.4 1 0 0 1 1 1 0 Pro-corazonin SAP PF02037.27 EGC38535.1 - 2.4e-10 39.9 0.0 3.2e-08 33.1 0.0 2.7 2 0 0 2 2 2 2 SAP domain SDA1 PF05285.12 EGC38535.1 - 6.5 6.1 72.2 1.1 8.7 24.5 4.2 4 0 0 4 4 4 0 SDA1 DUF3185 PF11381.8 EGC38536.1 - 0.012 15.6 2.7 2.4 8.2 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF3760 PF12586.8 EGC38536.1 - 0.058 13.6 0.0 15 5.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3760) Dor1 PF04124.12 EGC38537.1 - 5.4e-69 232.4 16.7 5.4e-69 232.4 16.7 3.0 3 1 0 3 3 3 1 Dor1-like family NPL PF17800.1 EGC38538.1 - 3.2e-14 53.4 0.1 3.2e-14 53.4 0.1 2.3 1 1 1 2 2 2 1 Nucleoplasmin-like domain Nucleoplasmin PF03066.15 EGC38538.1 - 0.032 14.7 0.0 0.087 13.3 0.0 1.8 1 0 0 1 1 1 0 Nucleoplasmin/nucleophosmin domain RR_TM4-6 PF06459.12 EGC38538.1 - 8.6 6.1 20.6 16 5.2 20.6 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP PF05725.12 EGC38540.1 - 1.6e-61 204.2 42.0 3.7e-14 52.6 0.1 14.0 6 4 6 13 13 13 13 FNIP Repeat MitMem_reg PF13012.6 EGC38540.1 - 0.077 13.4 0.1 0.41 11.1 0.1 2.2 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function DUF3585 PF12130.8 EGC38541.1 - 0.56 10.3 3.5 0.27 11.4 0.6 2.0 2 0 0 2 2 2 0 Bivalent Mical/EHBP Rab binding domain LAGLIDADG_1 PF00961.19 EGC38542.1 - 8.9e-08 33.0 5.1 0.00031 21.7 0.1 3.2 3 0 0 3 3 3 2 LAGLIDADG endonuclease Rsa3 PF14615.6 EGC38543.1 - 3.2e-15 55.4 0.9 8.8e-15 54.0 0.9 1.8 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DSPc PF00782.20 EGC38544.1 - 4.9e-19 68.5 0.5 7.6e-19 67.8 0.5 1.3 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.12 EGC38544.1 - 0.0001 22.0 0.7 0.00014 21.6 0.1 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.6 EGC38544.1 - 0.00012 22.2 0.0 0.00021 21.5 0.0 1.4 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase PF00102.27 EGC38544.1 - 0.0028 17.2 0.5 0.005 16.4 0.3 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGC38544.1 - 0.0033 17.0 0.0 0.0063 16.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.6 EGC38544.1 - 0.0035 17.3 0.0 0.0049 16.9 0.0 1.2 1 0 0 1 1 1 1 Tyrosine phosphatase family Ig_4 PF16680.5 EGC38544.1 - 0.069 13.4 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 T-cell surface glycoprotein CD3 delta chain Init_tRNA_PT PF04179.12 EGC38544.1 - 0.07 13.4 0.0 0.12 12.7 0.0 1.3 1 0 0 1 1 1 0 Rit1 DUSP-like domain DUF1442 PF07279.11 EGC38544.1 - 0.1 11.9 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PIP5K PF01504.18 EGC38545.1 - 3.1e-70 236.5 7.3 3.1e-70 236.5 7.3 1.9 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Smg8_Smg9 PF10220.9 EGC38546.1 - 3.3e-57 194.5 4.1 1e-34 120.1 0.0 3.3 2 1 1 3 3 3 3 Smg8_Smg9 Folliculin PF11704.8 EGC38546.1 - 0.04 13.8 5.9 0.91 9.4 0.2 2.4 2 0 0 2 2 2 0 Vesicle coat protein involved in Golgi to plasma membrane transport POX PF07526.11 EGC38546.1 - 1.8 9.1 6.1 2.3 8.8 1.6 2.4 2 0 0 2 2 2 0 Associated with HOX NST1 PF13945.6 EGC38546.1 - 5.6 7.0 27.8 9.2 6.3 20.5 2.6 2 0 0 2 2 2 0 Salt tolerance down-regulator MID_MedPIWI PF18296.1 EGC38546.1 - 9.3 6.0 18.9 3.2 7.5 1.1 2.8 3 0 0 3 3 3 0 MID domain of medPIWI CH PF00307.31 EGC38547.1 - 4.8e-22 78.2 0.0 5.2e-22 78.1 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC38547.1 - 1.1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain MeaB PF03308.16 EGC38549.1 - 1.2e-88 296.6 0.0 1.5e-88 296.3 0.0 1.1 1 0 0 1 1 1 1 Methylmalonyl Co-A mutase-associated GTPase MeaB cobW PF02492.19 EGC38549.1 - 4.3e-06 26.4 0.2 7.2e-05 22.4 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.17 EGC38549.1 - 5.5e-06 26.3 0.4 2.8e-05 24.0 0.0 2.2 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_24 PF13479.6 EGC38549.1 - 0.00029 20.6 1.4 0.0006 19.6 0.1 2.2 2 1 1 3 3 3 1 AAA domain DAP3 PF10236.9 EGC38549.1 - 0.00042 19.6 1.0 0.042 13.0 0.0 3.0 2 1 1 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_30 PF13604.6 EGC38549.1 - 0.0017 18.1 0.0 0.0028 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA domain NTPase_1 PF03266.15 EGC38549.1 - 0.0019 18.1 0.1 0.0046 16.9 0.1 1.7 1 0 0 1 1 1 1 NTPase MMR_HSR1 PF01926.23 EGC38549.1 - 0.0031 17.6 0.1 0.022 14.8 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_33 PF13671.6 EGC38549.1 - 0.0054 16.9 0.0 0.012 15.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC38549.1 - 0.0096 16.5 5.5 0.01 16.4 0.2 2.7 3 0 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EGC38549.1 - 0.022 14.5 0.0 0.065 13.0 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein ABC_tran PF00005.27 EGC38549.1 - 0.022 15.3 1.3 0.036 14.6 0.2 1.9 1 1 1 2 2 2 0 ABC transporter Thymidylate_kin PF02223.17 EGC38549.1 - 0.033 13.9 0.2 0.086 12.5 0.0 1.8 2 0 0 2 2 1 0 Thymidylate kinase AAA_29 PF13555.6 EGC38549.1 - 0.04 13.7 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_10 PF12846.7 EGC38549.1 - 0.04 12.8 1.0 0.067 12.1 0.0 1.8 2 1 0 2 2 2 0 AAA-like domain PRK PF00485.18 EGC38549.1 - 0.056 13.2 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Zeta_toxin PF06414.12 EGC38549.1 - 0.06 12.6 0.1 0.16 11.2 0.1 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.6 EGC38549.1 - 0.061 13.8 1.6 3.1 8.2 0.1 2.7 2 0 0 2 2 2 0 AAA domain APS_kinase PF01583.20 EGC38549.1 - 0.061 13.2 0.0 0.28 11.1 0.0 2.1 2 1 1 3 3 3 0 Adenylylsulphate kinase DUF463 PF04317.12 EGC38549.1 - 0.066 12.1 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 YcjX-like family, DUF463 AAA_22 PF13401.6 EGC38549.1 - 0.073 13.3 0.1 0.22 11.8 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGC38549.1 - 0.074 13.5 0.0 0.21 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGC38549.1 - 0.096 13.1 0.1 0.43 11.0 0.1 2.2 1 0 0 1 1 1 0 RNA helicase CbiA PF01656.23 EGC38549.1 - 0.11 12.6 0.1 0.32 11.0 0.0 1.9 2 0 0 2 2 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_19 PF13245.6 EGC38549.1 - 0.11 12.8 0.3 0.19 12.1 0.3 1.7 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC38549.1 - 0.18 12.0 0.1 0.41 10.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.6 EGC38549.1 - 0.18 12.2 0.1 0.41 11.0 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain p450 PF00067.22 EGC38549.1 - 0.54 8.9 6.8 0.1 11.3 2.1 1.8 2 0 0 2 2 2 0 Cytochrome P450 AMP-binding PF00501.28 EGC38550.1 - 1.1e-62 212.0 0.0 1.3e-62 211.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC38550.1 - 8.3e-14 51.3 4.7 2.9e-13 49.5 3.7 2.4 2 0 0 2 2 2 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC38550.1 - 5.1e-12 46.6 0.0 1.1e-11 45.6 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CLASP_N PF12348.8 EGC38551.1 - 2.5e-47 161.3 5.4 2.5e-47 161.3 5.4 1.9 2 0 0 2 2 2 1 CLASP N terminal HEAT PF02985.22 EGC38551.1 - 0.84 10.1 2.2 4.2 7.9 0.0 3.2 4 0 0 4 4 4 0 HEAT repeat PCI PF01399.27 EGC38552.1 - 5.3e-09 36.5 0.9 1.1e-08 35.5 0.9 1.5 1 0 0 1 1 1 1 PCI domain CSN7a_helixI PF18392.1 EGC38552.1 - 0.012 15.5 0.8 0.023 14.6 0.1 1.9 2 0 0 2 2 2 0 COP9 signalosome complex subunit 7a helix I domain DUF960 PF06124.11 EGC38552.1 - 0.21 12.3 2.4 0.46 11.2 1.0 2.2 1 1 1 2 2 2 0 Staphylococcal protein of unknown function (DUF960) Abhydrolase_3 PF07859.13 EGC38553.1 - 2.9e-44 151.5 0.0 3.5e-44 151.2 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGC38553.1 - 2.5e-12 46.3 0.4 3.8e-12 45.8 0.4 1.3 1 0 0 1 1 1 1 Steryl acetyl hydrolase COesterase PF00135.28 EGC38553.1 - 1.3e-07 30.9 0.2 2.9e-05 23.2 0.0 2.4 2 1 0 2 2 2 2 Carboxylesterase family Esterase PF00756.20 EGC38553.1 - 0.0067 16.1 0.0 0.54 9.9 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Chlorophyllase2 PF12740.7 EGC38553.1 - 0.063 12.2 0.0 0.11 11.4 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme AXE1 PF05448.12 EGC38553.1 - 0.07 11.8 0.0 0.12 11.0 0.0 1.4 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Mon2_C PF16206.5 EGC38554.1 - 2.5e-67 227.7 8.5 1.4e-39 136.0 0.4 3.3 2 1 0 2 2 2 2 C-terminal region of Mon2 protein DCB PF16213.5 EGC38554.1 - 3.5e-56 189.7 11.4 3.5e-56 189.7 11.4 4.4 5 0 0 5 5 5 1 Dimerisation and cyclophilin-binding domain of Mon2 Sec7_N PF12783.7 EGC38554.1 - 1.6e-39 135.4 0.6 1.6e-39 135.4 0.6 5.7 5 0 0 5 5 5 2 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.10 EGC38554.1 - 1.8e-08 34.1 0.9 1.8e-08 34.1 0.9 5.5 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) Pox_A_type_inc PF04508.12 EGC38555.1 - 0.15 11.9 3.9 0.12 12.3 1.2 2.3 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-C4H2 PF10146.9 EGC38555.1 - 1.3 9.3 38.8 0.49 10.7 15.3 2.5 1 1 1 2 2 2 0 Zinc finger-containing protein Ras PF00071.22 EGC38556.1 - 3.5e-12 46.2 11.3 3.8e-05 23.3 1.4 3.7 1 1 1 2 2 2 2 Ras family Roc PF08477.13 EGC38556.1 - 0.00032 20.9 1.6 0.001 19.3 0.2 2.6 3 1 0 3 3 3 1 Ras of Complex, Roc, domain of DAPkinase SurA_N_3 PF13624.6 EGC38556.1 - 0.62 9.8 7.9 0.4 10.5 0.8 2.9 3 0 0 3 3 3 0 SurA N-terminal domain CRA PF06589.11 EGC38557.1 - 0.0073 16.4 6.6 0.0073 16.4 6.6 2.6 2 1 0 2 2 2 1 Circumsporozoite-related antigen (CRA) MAP17 PF15807.5 EGC38557.1 - 0.038 14.2 0.5 0.038 14.2 0.5 3.2 2 1 1 3 3 3 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 Nucleoside_tran PF01733.18 EGC38557.1 - 0.14 11.5 0.4 0.26 10.6 0.4 1.4 1 0 0 1 1 1 0 Nucleoside transporter Tetraspanin PF00335.20 EGC38557.1 - 0.14 11.9 3.0 0.19 11.4 3.0 1.3 1 0 0 1 1 1 0 Tetraspanin family TFIIA PF03153.13 EGC38557.1 - 0.29 11.1 31.4 0.46 10.4 31.4 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4006 PF13179.6 EGC38557.1 - 1.9 8.5 6.7 0.6 10.1 2.6 2.3 1 1 1 2 2 2 0 Family of unknown function (DUF4006) HCO3_cotransp PF00955.21 EGC38557.1 - 2 7.2 4.1 3.8 6.2 4.1 1.5 1 0 0 1 1 1 0 HCO3- transporter family OATP PF03137.20 EGC38557.1 - 6.6 4.9 4.9 0.49 8.6 0.3 1.5 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family EamA PF00892.20 EGC38558.1 - 7.7e-13 48.8 35.3 1.2e-08 35.2 13.5 3.0 3 0 0 3 3 3 2 EamA-like transporter family CENP-B_dimeris PF09026.10 EGC38558.1 - 0.0093 16.3 4.0 0.32 11.4 2.0 2.5 2 1 0 2 2 2 1 Centromere protein B dimerisation domain ETRAMP PF09716.10 EGC38558.1 - 0.021 14.8 9.3 0.16 12.1 2.3 3.4 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Pox_G9-A16 PF03003.16 EGC38558.1 - 1.4 8.7 9.7 16 5.2 0.2 2.6 3 0 0 3 3 3 0 Pox virus entry-fusion-complex G9/A16 AtpR PF12966.7 EGC38558.1 - 1.6 9.2 11.0 1 9.8 3.9 2.8 2 1 0 2 2 2 0 N-ATPase, AtpR subunit SelK_SelG PF10961.8 EGC38558.1 - 1.7 9.3 0.0 1.7 9.3 0.0 3.1 3 0 0 3 3 3 0 Selenoprotein SelK_SelG LRRC37AB_C PF14914.6 EGC38558.1 - 2.1 8.3 5.7 5.3 6.9 0.9 2.3 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain PsaM PF07465.13 EGC38558.1 - 3.7 7.3 6.4 4.2 7.2 0.1 2.4 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) Orf78 PF06024.12 EGC38558.1 - 8.2 6.8 18.0 19 5.6 1.2 3.8 3 1 0 3 3 3 0 Orf78 (ac78) AKAP_110 PF05716.13 EGC38559.1 - 0.0016 16.8 0.3 0.0021 16.4 0.3 1.1 1 0 0 1 1 1 1 A-kinase anchor protein 110 kDa (AKAP 110) Med19 PF10278.9 EGC38559.1 - 0.059 13.3 0.8 0.059 13.3 0.8 3.1 2 2 1 3 3 3 0 Mediator of RNA pol II transcription subunit 19 TFIIA PF03153.13 EGC38559.1 - 0.067 13.2 20.8 0.084 12.9 20.8 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit VIR_N PF15912.5 EGC38559.1 - 0.95 9.0 16.8 1.5 8.3 16.8 1.3 1 0 0 1 1 1 0 Virilizer, N-terminal Nucleo_P87 PF07267.11 EGC38559.1 - 8.5 5.1 18.4 10 4.8 18.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Vta1 PF04652.16 EGC38560.1 - 1.8e-33 115.6 0.1 1.8e-33 115.6 0.1 3.4 2 1 0 2 2 2 1 Vta1 like Vta1_C PF18097.1 EGC38560.1 - 2.7e-14 52.6 2.4 2.7e-14 52.6 2.4 2.6 2 0 0 2 2 2 1 Vta1 C-terminal domain ATG16 PF08614.11 EGC38560.1 - 0.89 9.7 27.9 0.69 10.1 16.8 2.7 3 0 0 3 3 3 0 Autophagy protein 16 (ATG16) Exonuc_VII_L PF02601.15 EGC38560.1 - 1 8.9 12.2 1.1 8.8 10.8 1.8 2 0 0 2 2 2 0 Exonuclease VII, large subunit UPF0242 PF06785.11 EGC38560.1 - 1.2 9.2 23.6 0.73 9.9 19.5 2.2 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus AAA_23 PF13476.6 EGC38560.1 - 2.9 8.3 23.5 0.018 15.6 12.2 2.4 2 1 0 2 2 2 0 AAA domain DUF3450 PF11932.8 EGC38560.1 - 6.1 6.1 24.8 15 4.8 24.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Rav1p_C PF12234.8 EGC38561.1 - 0.022 13.2 0.3 0.033 12.6 0.3 1.2 1 0 0 1 1 1 0 RAVE protein 1 C terminal NusG_add PF18298.1 EGC38561.1 - 0.097 12.9 0.1 0.42 10.8 0.1 2.0 2 0 0 2 2 2 0 NusG additional domain Melibiase_2 PF16499.5 EGC38562.1 - 1.2e-70 238.0 5.2 1.7e-70 237.4 5.2 1.3 1 0 0 1 1 1 1 Alpha galactosidase A Melibiase_C PF17801.1 EGC38562.1 - 5.2e-20 71.3 0.7 2.7e-19 69.0 0.2 2.2 2 0 0 2 2 2 1 Alpha galactosidase C-terminal beta sandwich domain Melibiase_2_C PF17450.2 EGC38562.1 - 3.2e-05 24.1 0.0 5.6e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Alpha galactosidase A C-terminal beta sandwich domain Melibiase PF02065.18 EGC38562.1 - 0.00042 19.4 0.0 0.00095 18.2 0.0 1.5 2 0 0 2 2 2 1 Melibiase Glyco_hydro_30C PF17189.4 EGC38562.1 - 0.028 14.6 0.0 0.053 13.7 0.0 1.5 1 0 0 1 1 1 0 Glycosyl hydrolase family 30 beta sandwich domain HSP20 PF00011.21 EGC38563.1 - 0.014 15.6 0.0 0.034 14.3 0.0 1.7 1 0 0 1 1 1 0 Hsp20/alpha crystallin family GBP PF02263.19 EGC38563.1 - 0.019 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Hema_HEFG PF02710.14 EGC38563.1 - 0.064 13.5 0.4 0.13 12.5 0.4 1.5 1 0 0 1 1 1 0 Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein Pyr_redox_2 PF07992.14 EGC38564.1 - 9.7e-48 162.9 0.0 1.3e-47 162.5 0.0 1.2 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.27 EGC38564.1 - 3e-09 37.3 0.3 1.4e-08 35.2 0.1 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DUF4659 PF15558.6 EGC38564.1 - 0.061 12.2 0.3 0.1 11.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) KduI PF04962.12 EGC38564.1 - 0.067 12.5 0.1 0.11 11.9 0.1 1.2 1 0 0 1 1 1 0 KduI/IolB family NAD_binding_9 PF13454.6 EGC38564.1 - 0.11 12.5 0.2 14 5.6 0.0 2.9 2 1 1 3 3 3 0 FAD-NAD(P)-binding DUF5584 PF17822.1 EGC38564.1 - 0.14 11.6 1.1 16 4.9 0.0 2.9 2 1 1 3 3 3 0 Family of unknown function (DUF5584) tRNA_lig_CPD PF08302.11 EGC38565.1 - 1.6 8.1 12.2 1.8 8.0 12.2 1.0 1 0 0 1 1 1 0 Fungal tRNA ligase phosphodiesterase domain SLD3 PF08639.10 EGC38566.1 - 0.33 9.7 0.2 0.43 9.3 0.2 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 DNA_pol_B PF00136.21 EGC38569.1 - 1.7e-96 323.7 0.1 4.8e-96 322.3 0.1 1.8 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGC38569.1 - 1.5e-18 67.0 20.8 4.1e-12 45.9 4.2 4.8 4 1 0 4 4 4 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGC38569.1 - 1.4e-13 51.0 7.5 5.1e-13 49.3 7.5 2.1 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta COX5A PF02284.16 EGC38569.1 - 1.3 9.0 4.9 3.7 7.6 0.0 3.0 2 0 0 2 2 2 0 Cytochrome c oxidase subunit Va adh_short PF00106.25 EGC38570.1 - 9.9e-15 54.5 0.0 5.4e-14 52.1 0.0 1.8 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC38570.1 - 1.1e-13 51.3 0.0 2.7e-13 50.0 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGC38570.1 - 0.0065 15.9 0.0 0.017 14.6 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGC38570.1 - 0.026 13.6 0.0 0.036 13.2 0.0 1.3 1 1 0 1 1 1 0 RmlD substrate binding domain Semialdhyde_dh PF01118.24 EGC38570.1 - 0.091 13.2 0.0 0.14 12.6 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.10 EGC38570.1 - 0.1 12.5 0.0 1.2 9.1 0.0 2.1 1 1 1 2 2 2 0 KR domain NmrA PF05368.13 EGC38570.1 - 0.12 11.9 0.0 0.17 11.4 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family FtsJ PF01728.19 EGC38570.1 - 0.14 12.2 0.0 0.19 11.8 0.0 1.2 1 0 0 1 1 1 0 FtsJ-like methyltransferase Sin_N PF04801.13 EGC38572.1 - 1.2e-112 377.3 6.0 2.3e-109 366.5 5.3 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region TFIIE-A_C PF11521.8 EGC38572.1 - 6.9 7.0 14.2 0.99 9.8 3.1 3.8 4 0 0 4 4 4 0 C-terminal general transcription factor TFIIE alpha Erf4 PF10256.9 EGC38573.1 - 2.9e-06 27.4 0.0 3.4e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.9 EGC38573.1 - 0.00019 20.3 0.2 0.00026 19.9 0.2 1.1 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) DUF4064 PF13273.6 EGC38573.1 - 0.0011 19.2 1.0 0.49 10.7 0.5 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF4064) Yip1 PF04893.17 EGC38573.1 - 0.0054 16.5 0.0 0.0077 16.0 0.0 1.2 1 0 0 1 1 1 1 Yip1 domain DHHC PF01529.20 EGC38573.1 - 0.031 14.4 0.1 0.052 13.7 0.1 1.3 1 0 0 1 1 1 0 DHHC palmitoyltransferase Tetraspanin PF00335.20 EGC38573.1 - 0.56 9.9 4.6 0.13 12.0 0.5 2.0 2 1 1 3 3 3 0 Tetraspanin family TMEM171 PF15471.6 EGC38573.1 - 0.66 8.9 3.0 0.41 9.6 0.7 1.6 1 1 0 1 1 1 0 Transmembrane protein family 171 FNIP PF05725.12 EGC38574.1 - 5e-198 641.2 107.5 3.1e-16 59.2 1.0 12.1 6 2 10 16 16 16 16 FNIP Repeat Glyco_hydro_65C PF03633.15 EGC38574.1 - 0.084 12.8 5.0 56 3.8 0.0 8.1 12 0 0 12 12 12 0 Glycosyl hydrolase family 65, C-terminal domain LRR_1 PF00560.33 EGC38574.1 - 2.8 8.8 27.0 68 4.6 0.3 10.6 7 5 1 8 8 8 0 Leucine Rich Repeat CAP PF00188.26 EGC38575.1 - 2.7e-09 37.9 0.0 2.7e-09 37.9 0.0 2.9 3 1 0 3 3 3 1 Cysteine-rich secretory protein family Mucin PF01456.17 EGC38575.1 - 0.076 13.0 13.4 0.055 13.5 8.0 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein LRR_8 PF13855.6 EGC38576.1 - 5.9e-45 150.9 57.4 3.4e-08 33.1 2.9 9.2 4 2 5 10 10 10 10 Leucine rich repeat LRR_4 PF12799.7 EGC38576.1 - 3.6e-42 141.6 74.6 1.2e-06 28.8 0.8 11.2 1 1 10 14 14 14 14 Leucine Rich repeats (2 copies) LRR_1 PF00560.33 EGC38576.1 - 1.7e-09 36.9 59.1 1.2 9.9 0.3 15.9 19 0 0 19 19 19 7 Leucine Rich Repeat LRRNT PF01462.18 EGC38576.1 - 0.0052 16.4 1.4 1.3 8.7 0.0 5.1 7 0 0 7 7 7 1 Leucine rich repeat N-terminal domain Dcc1 PF09724.9 EGC38577.1 - 7.3e-83 278.6 4.6 1.6e-82 277.5 4.6 1.5 1 1 0 1 1 1 1 Sister chromatid cohesion protein Dcc1 HTH_Mga PF08280.11 EGC38577.1 - 0.00056 19.9 2.3 0.0011 18.9 1.0 2.2 1 1 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Tau95 PF09734.9 EGC38577.1 - 0.081 13.7 0.1 0.17 12.7 0.1 1.7 1 0 0 1 1 1 0 RNA polymerase III transcription factor (TF)IIIC subunit HTH domain FIVAR PF07554.13 EGC38577.1 - 0.52 11.1 5.7 2 9.2 5.7 2.0 1 0 0 1 1 1 0 FIVAR domain Defensin_propep PF00879.18 EGC38578.1 - 0.97 9.7 4.5 1.4 9.2 4.5 1.2 1 0 0 1 1 1 0 Defensin propeptide DUF998 PF06197.13 EGC38580.1 - 4e-05 23.3 0.0 0.0001 21.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF998) PAP2 PF01569.21 EGC38580.1 - 0.13 12.0 1.6 1.6 8.5 0.8 2.4 1 1 0 1 1 1 0 PAP2 superfamily BacA PF02673.18 EGC38580.1 - 0.16 11.6 4.4 5.1 6.7 1.8 2.2 1 1 1 2 2 2 0 Bacitracin resistance protein BacA Cation_ATPase_C PF00689.21 EGC38580.1 - 0.38 10.4 8.6 0.18 11.5 6.0 1.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus EamA PF00892.20 EGC38580.1 - 0.69 10.1 13.1 0.32 11.2 3.6 3.1 1 1 2 3 3 3 0 EamA-like transporter family EptA_B_N PF08019.12 EGC38580.1 - 4 7.3 9.1 0.34 10.8 1.0 2.8 2 1 1 3 3 3 0 Phosphoethanolamine transferase EptA/EptB DUF2975 PF11188.8 EGC38580.1 - 4.1 7.3 7.2 0.4 10.6 1.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2975) Nucleoside_tran PF01733.18 EGC38580.1 - 4.3 6.6 12.6 1 8.6 1.4 2.7 2 1 0 2 2 2 0 Nucleoside transporter Paf67 PF10255.9 EGC38581.1 - 7e-126 420.5 13.0 1.1e-125 419.8 13.0 1.3 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.27 EGC38581.1 - 0.0044 17.5 3.0 0.0045 17.5 0.5 2.3 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.17 EGC38581.1 - 0.0061 16.6 0.1 0.031 14.4 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SAM_PNT PF02198.16 EGC38581.1 - 0.013 15.4 0.1 0.057 13.4 0.0 2.1 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain EPL1 PF10513.9 EGC38581.1 - 0.026 14.9 4.4 0.066 13.6 4.4 1.7 1 0 0 1 1 1 0 Enhancer of polycomb-like Fis1_TPR_C PF14853.6 EGC38581.1 - 0.2 11.8 2.6 1.6 8.9 1.4 2.9 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat p450 PF00067.22 EGC38582.1 - 4.5e-86 289.4 0.0 5.1e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M90 PF06167.12 EGC38582.1 - 0.03 13.9 0.1 0.051 13.2 0.1 1.3 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 EH_Signature PF15611.6 EGC38583.1 - 0.0019 17.7 4.7 1.8 7.9 0.9 3.1 1 1 1 2 2 2 2 EH_Signature domain YfcL PF08891.11 EGC38583.1 - 0.011 16.1 0.6 0.011 16.1 0.6 4.0 4 0 0 4 4 4 0 YfcL protein SLAM PF06214.11 EGC38583.1 - 0.029 14.4 1.1 0.029 14.4 1.1 2.6 2 0 0 2 2 2 0 Signaling lymphocytic activation molecule (SLAM) protein Mem_trans PF03547.18 EGC38583.1 - 0.34 9.3 3.2 0.74 8.1 3.2 1.5 1 0 0 1 1 1 0 Membrane transport protein FNIP PF05725.12 EGC38584.1 - 2.9e-81 267.4 87.5 5e-11 42.6 4.0 13.3 8 3 4 13 13 13 12 FNIP Repeat Pkinase PF00069.25 EGC38584.1 - 4.1e-42 144.4 3.3 3e-41 141.5 3.3 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38584.1 - 3.3e-29 102.0 0.1 2e-27 96.1 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC38584.1 - 4.3e-05 22.5 0.1 6.8e-05 21.8 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC38584.1 - 0.00074 18.9 0.1 0.0012 18.2 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RTP1_C1 PF10363.9 EGC38584.1 - 0.036 14.3 0.0 0.088 13.0 0.0 1.6 1 0 0 1 1 1 0 Required for nuclear transport of RNA pol II C-terminus 1 APH PF01636.23 EGC38584.1 - 0.1 12.5 0.3 0.17 11.8 0.3 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SQS_PSY PF00494.19 EGC38585.1 - 5e-42 144.2 0.0 6.4e-42 143.9 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase Ketoacyl-synt_C PF02801.22 EGC38587.1 - 5.6e-25 87.7 0.0 1.8e-24 86.0 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.26 EGC38587.1 - 5.8e-21 75.2 0.0 1.1e-20 74.3 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.12 EGC38587.1 - 1.7e-18 67.2 0.0 1.7e-18 67.2 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC38587.1 - 2.8e-15 56.7 0.5 6e-15 55.7 0.5 1.6 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC38587.1 - 3.7e-11 42.8 0.0 5.3e-11 42.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_11 PF08241.12 EGC38587.1 - 8.6e-08 32.7 0.0 2.5e-07 31.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38587.1 - 5.9e-07 30.1 0.0 1.9e-06 28.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38587.1 - 8.3e-07 29.0 0.0 2.7e-06 27.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38587.1 - 6.5e-05 22.8 0.0 0.00019 21.3 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.11 EGC38587.1 - 0.0063 16.2 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Ubie_methyltran PF01209.18 EGC38587.1 - 0.008 15.5 0.0 0.015 14.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Glyco_hydro_47 PF01532.20 EGC38588.1 - 2e-135 452.3 0.3 2.3e-135 452.1 0.3 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 EGC38588.1 - 0.0006 19.4 1.8 2.1 7.7 0.0 3.8 3 1 1 4 4 4 2 Glycosyl hydrolase family 76 GlcNAc_2-epim PF07221.11 EGC38588.1 - 0.0032 16.8 0.0 10 5.3 0.0 3.5 4 0 0 4 4 4 3 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) ketoacyl-synt PF00109.26 EGC38589.1 - 1.1e-62 211.9 0.0 1.9e-62 211.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38589.1 - 6.8e-43 147.4 0.0 1.2e-42 146.6 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38589.1 - 9.9e-31 106.2 0.0 6.6e-30 103.5 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38589.1 - 5.9e-25 88.2 0.0 1.6e-24 86.8 0.0 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC38589.1 - 2.4e-21 76.3 0.0 3.7e-21 75.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC38589.1 - 9.1e-20 71.3 3.5 2.5e-19 69.9 0.0 3.6 2 0 0 2 2 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC38589.1 - 1e-15 58.2 0.4 3.6e-15 56.4 0.1 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38589.1 - 1.9e-10 41.9 0.0 1.1e-09 39.4 0.0 2.2 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38589.1 - 4.2e-06 26.6 0.0 9.8e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38589.1 - 9.9e-06 25.1 0.0 2.3e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGC38589.1 - 5e-05 23.9 0.0 0.00022 21.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC38589.1 - 0.00018 21.4 0.0 0.00057 19.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38589.1 - 0.015 15.1 4.7 0.33 10.7 0.0 4.0 3 0 0 3 3 3 0 Methyltransferase domain DUF1430 PF07242.11 EGC38589.1 - 0.024 14.9 1.0 0.14 12.4 0.2 2.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1430) Cu PF17563.2 EGC38589.1 - 0.068 13.4 0.0 0.16 12.2 0.0 1.6 1 0 0 1 1 1 0 Cupiennin PP-binding PF00550.25 EGC38589.1 - 0.14 12.5 0.1 0.35 11.2 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site Glyco_hydro_47 PF01532.20 EGC38590.1 - 1.3e-19 70.4 0.0 1.4e-19 70.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ketoacyl-synt PF00109.26 EGC38591.1 - 2.4e-62 210.8 0.0 4.1e-62 210.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38591.1 - 9.2e-43 146.9 0.0 1.7e-42 146.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38591.1 - 8.6e-31 106.4 0.0 5.5e-30 103.8 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38591.1 - 4.5e-26 91.9 0.1 1.2e-25 90.4 0.1 1.8 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC38591.1 - 7.5e-22 77.9 0.0 1.1e-21 77.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC38591.1 - 7.7e-20 71.5 0.1 7.7e-20 71.5 0.1 4.1 3 0 0 3 3 2 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC38591.1 - 2.8e-15 56.7 0.6 9.2e-15 55.1 0.2 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38591.1 - 3.3e-10 41.2 0.0 2.3e-09 38.4 0.0 2.4 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.6 EGC38591.1 - 5.8e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.12 EGC38591.1 - 2.6e-06 27.3 0.1 6e-06 26.1 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC38591.1 - 6.2e-06 26.8 0.0 3.6e-05 24.3 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC38591.1 - 9.2e-06 25.2 0.0 2.3e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.6 EGC38591.1 - 6e-05 22.9 3.4 0.0018 18.1 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain DUF1430 PF07242.11 EGC38591.1 - 0.019 15.2 0.2 0.14 12.4 0.2 2.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1430) PP-binding PF00550.25 EGC38591.1 - 0.033 14.5 0.1 0.081 13.3 0.1 1.7 1 0 0 1 1 1 0 Phosphopantetheine attachment site DUF4834 PF16118.5 EGC38593.1 - 0.0013 19.7 3.3 0.0013 19.7 3.3 2.9 1 1 1 2 2 2 1 Domain of unknown function (DUF4834) DUF4407 PF14362.6 EGC38593.1 - 0.088 12.1 7.8 0.12 11.7 7.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) ABC2_membrane_3 PF12698.7 EGC38593.1 - 0.22 10.6 0.6 0.23 10.5 0.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein EVI2A PF05399.11 EGC38593.1 - 0.32 10.6 19.1 30 4.1 19.1 2.2 1 1 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Pox_A21 PF05323.12 EGC38593.1 - 1.5 9.4 5.1 0.19 12.3 0.3 1.9 2 1 0 2 2 2 0 Poxvirus A21 Protein Tho2 PF11262.8 EGC38593.1 - 2 7.6 26.1 0.77 8.9 15.5 2.1 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 CSG2 PF16965.5 EGC38593.1 - 3.3 6.6 12.5 0.063 12.2 1.8 2.0 2 0 0 2 2 2 0 Ceramide synthase regulator Caldesmon PF02029.15 EGC38593.1 - 4.8 5.8 34.3 6.7 5.4 34.3 1.2 1 0 0 1 1 1 0 Caldesmon zf-RING_2 PF13639.6 EGC38594.1 - 1.6e-10 41.1 9.0 2.3e-10 40.6 9.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC38594.1 - 3.6e-09 36.3 8.0 5.4e-09 35.8 8.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC38594.1 - 1.6e-08 34.3 6.3 2.4e-08 33.7 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38594.1 - 2.7e-08 33.6 9.4 4.3e-08 32.9 9.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC38594.1 - 3e-05 24.1 5.4 7.1e-05 22.9 5.4 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGC38594.1 - 6.6e-05 22.9 4.2 0.00013 21.9 4.2 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC38594.1 - 0.00028 21.1 8.9 0.00061 20.0 8.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_4 PF14570.6 EGC38594.1 - 0.0012 18.6 9.0 0.0025 17.6 9.0 1.6 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGC38594.1 - 0.002 18.1 7.4 0.0039 17.1 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_11 PF17123.5 EGC38594.1 - 0.0027 17.4 5.1 0.0064 16.2 5.1 1.6 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGC38594.1 - 0.011 15.5 6.5 0.028 14.3 6.2 1.8 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 RPN2_C PF18004.1 EGC38594.1 - 0.041 13.8 10.5 0.053 13.4 10.5 1.1 1 0 0 1 1 1 0 26S proteasome regulatory subunit RPN2 C-terminal domain SpoIIP PF07454.11 EGC38594.1 - 0.061 12.8 3.1 0.055 12.9 3.1 1.1 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) zf-RING_10 PF16685.5 EGC38594.1 - 0.063 13.4 2.8 0.1 12.8 2.8 1.3 1 0 0 1 1 1 0 zinc RING finger of MSL2 DDHD PF02862.17 EGC38594.1 - 0.16 12.1 1.8 0.15 12.2 1.8 1.1 1 0 0 1 1 1 0 DDHD domain V_ATPase_I PF01496.19 EGC38594.1 - 0.16 9.9 4.0 0.14 10.0 4.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-RING_6 PF14835.6 EGC38594.1 - 0.21 11.5 2.5 0.46 10.4 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 EGC38594.1 - 0.21 11.2 4.0 0.32 10.6 4.0 1.2 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type NPR3 PF03666.13 EGC38594.1 - 0.37 9.5 6.4 0.42 9.4 6.4 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 zf-ANAPC11 PF12861.7 EGC38594.1 - 0.46 10.6 5.6 1.2 9.3 5.6 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger GPCR_chapero_1 PF11904.8 EGC38594.1 - 0.83 9.0 6.4 0.88 8.9 6.4 1.1 1 0 0 1 1 1 0 GPCR-chaperone Otopetrin PF03189.13 EGC38594.1 - 0.88 8.3 2.9 1.1 8.0 2.9 1.0 1 0 0 1 1 1 0 Otopetrin Connexin PF00029.19 EGC38594.1 - 1.1 9.0 7.1 1.2 8.8 7.1 1.2 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC38594.1 - 1.2 7.9 10.2 1.3 7.7 10.2 1.1 1 0 0 1 1 1 0 Presenilin Peptidase_U57 PF05582.12 EGC38594.1 - 1.3 8.2 4.5 1.6 8.0 4.5 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DZR PF12773.7 EGC38594.1 - 1.4 9.0 8.2 3.7 7.6 7.8 1.9 1 1 0 1 1 1 0 Double zinc ribbon CTU2 PF10288.9 EGC38594.1 - 1.8 8.8 19.1 7.6 6.8 17.2 2.3 2 1 0 2 2 2 0 Cytoplasmic tRNA 2-thiolation protein 2 Sec62 PF03839.16 EGC38594.1 - 2 7.9 4.7 2.3 7.7 4.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 IBR PF01485.21 EGC38594.1 - 2.1 8.6 11.4 4.9 7.5 8.9 2.4 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain CPSF100_C PF13299.6 EGC38594.1 - 2.4 8.3 8.3 3 8.0 8.3 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal PA26 PF04636.13 EGC38594.1 - 2.9 6.7 6.2 3 6.7 6.2 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) BT1 PF03092.16 EGC38594.1 - 2.9 6.0 7.9 3.4 5.8 7.9 1.0 1 0 0 1 1 1 0 BT1 family zinc_ribbon_9 PF14369.6 EGC38594.1 - 4 7.8 13.3 0.19 12.0 5.6 2.4 1 1 0 2 2 2 0 zinc-ribbon DUF3504 PF12012.8 EGC38594.1 - 4.3 7.2 10.0 5.8 6.8 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3504) NARP1 PF12569.8 EGC38594.1 - 5.7 5.7 14.1 6.5 5.5 14.1 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-HC5HC2H PF13771.6 EGC38594.1 - 6.3 7.1 10.6 2.1 8.7 7.8 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain eIF-3_zeta PF05091.12 EGC38594.1 - 6.9 5.5 11.6 8 5.3 11.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) FapA PF03961.13 EGC38594.1 - 6.9 5.2 7.2 8.3 4.9 7.2 1.0 1 0 0 1 1 1 0 Flagellar Assembly Protein A Neur_chan_memb PF02932.16 EGC38594.1 - 7.9 6.5 5.7 8.6 6.3 5.7 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3987 PF13148.6 EGC38594.1 - 8.7 5.2 10.9 11 4.9 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) TERB2 PF15101.6 EGC38594.1 - 9.2 6.3 8.0 11 6.0 8.0 1.1 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CMS1 PF14617.6 EGC38594.1 - 9.3 5.5 8.1 12 5.1 8.1 1.3 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit zf-RING_2 PF13639.6 EGC38596.1 - 5.7e-09 36.2 9.8 5.7e-09 36.2 9.8 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38596.1 - 1.1e-08 34.7 7.5 2.2e-08 33.8 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38596.1 - 3.6e-08 33.1 9.0 6.4e-08 32.3 9.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38596.1 - 5.1e-07 29.5 11.1 1.3e-06 28.1 11.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC38596.1 - 4.2e-05 23.5 5.0 9.3e-05 22.4 5.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38596.1 - 0.0004 20.3 8.9 0.0004 20.3 8.9 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC38596.1 - 0.0005 19.8 9.5 0.0012 18.6 9.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC38596.1 - 0.00075 19.7 5.9 0.0028 17.9 5.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGC38596.1 - 0.0031 17.2 7.3 0.0075 16.0 7.3 1.7 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGC38596.1 - 0.0034 17.2 8.2 0.015 15.2 8.1 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.6 EGC38596.1 - 0.0048 17.0 9.1 0.022 14.9 9.1 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC38596.1 - 0.053 13.4 1.7 0.11 12.4 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGC38596.1 - 0.14 12.2 1.5 0.3 11.2 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC38596.1 - 0.53 9.9 5.0 0.95 9.1 5.0 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-MIZ PF02891.20 EGC38596.1 - 1 9.1 7.4 2.2 8.1 7.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.7 EGC38596.1 - 2.4 8.2 8.4 14 5.8 8.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon DENN PF02141.21 EGC38597.1 - 3.8e-29 102.0 4.3 1.2e-25 90.5 0.1 3.3 2 1 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.18 EGC38597.1 - 4.7e-07 30.5 0.1 4.7e-07 30.5 0.1 3.2 3 0 0 3 3 3 1 uDENN domain BCS1_N PF08740.11 EGC38598.1 - 1.8e-46 158.5 0.3 1.8e-46 158.5 0.3 1.7 2 1 0 2 2 2 1 BCS1 N terminal AAA PF00004.29 EGC38598.1 - 5.1e-16 59.3 0.1 6.5e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.6 EGC38598.1 - 0.00023 21.6 0.0 0.0005 20.5 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.13 EGC38598.1 - 0.0013 17.9 0.0 0.0022 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RNA_helicase PF00910.22 EGC38598.1 - 0.01 16.2 0.0 0.034 14.5 0.0 2.0 2 0 0 2 2 1 0 RNA helicase DUF3899 PF13038.6 EGC38598.1 - 0.021 15.3 0.0 0.047 14.2 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) PPV_E1_C PF00519.17 EGC38598.1 - 0.029 13.2 0.0 0.13 11.1 0.0 1.8 2 0 0 2 2 2 0 Papillomavirus helicase AAA_11 PF13086.6 EGC38598.1 - 0.031 14.1 0.0 0.052 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.6 EGC38598.1 - 0.032 14.0 0.0 0.077 12.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGC38598.1 - 0.033 14.7 0.1 0.082 13.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_22 PF13401.6 EGC38598.1 - 0.043 14.1 0.0 0.35 11.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.6 EGC38598.1 - 0.049 13.4 0.0 0.12 12.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATPase PF06745.13 EGC38598.1 - 0.05 12.9 0.0 0.13 11.6 0.0 1.7 1 1 0 1 1 1 0 KaiC AAA_5 PF07728.14 EGC38598.1 - 0.083 12.9 0.1 0.19 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.6 EGC38598.1 - 0.094 13.3 0.0 0.21 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain Guanylate_kin PF00625.21 EGC38598.1 - 0.11 12.1 0.1 29 4.3 0.0 3.1 2 1 1 3 3 3 0 Guanylate kinase TIP49 PF06068.13 EGC38598.1 - 0.12 11.6 0.1 1.1 8.4 0.0 2.0 2 0 0 2 2 2 0 TIP49 P-loop domain AAA_7 PF12775.7 EGC38598.1 - 0.12 11.9 0.0 0.3 10.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_25 PF13481.6 EGC38598.1 - 0.12 12.0 0.0 0.25 10.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain RuvB_N PF05496.12 EGC38598.1 - 0.13 12.0 0.0 0.23 11.2 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGC38598.1 - 0.14 12.3 0.0 0.26 11.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain Pkinase PF00069.25 EGC38599.1 - 9.8e-48 162.8 0.0 9.8e-48 162.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38599.1 - 1.3e-20 73.8 0.0 5.5e-20 71.7 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase Hid1 PF12722.7 EGC38599.1 - 0.12 10.5 12.5 0.17 10.0 12.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein LMBR1 PF04791.16 EGC38599.1 - 0.33 9.8 2.7 0.48 9.3 2.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein TFIIA PF03153.13 EGC38599.1 - 0.73 9.8 20.4 1.1 9.2 20.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spt20 PF12090.8 EGC38599.1 - 3.9 7.0 27.0 8.7 5.9 27.0 1.5 1 0 0 1 1 1 0 Spt20 family DUF4407 PF14362.6 EGC38599.1 - 4.1 6.7 6.9 6.3 6.1 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PAT1 PF09770.9 EGC38600.1 - 0.84 7.8 40.8 0.98 7.6 40.8 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 GREB1 PF15782.5 EGC38600.1 - 3.6 4.6 27.9 4.2 4.3 27.9 1.2 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer Activator_LAG-3 PF11498.8 EGC38600.1 - 4.9 6.0 67.2 6.1 5.7 67.2 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 K_trans PF02705.16 EGC38600.1 - 5.9 5.3 5.6 6.4 5.1 5.6 1.3 1 0 0 1 1 1 0 K+ potassium transporter TMEM174 PF15029.6 EGC38600.1 - 7.8 6.1 17.5 0.28 10.9 11.3 1.7 2 0 0 2 2 2 0 Transmembrane protein 174 ADH_zinc_N PF00107.26 EGC38601.1 - 5e-25 88.0 0.0 7.8e-25 87.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC38601.1 - 1.1e-12 49.2 0.0 2.7e-12 47.9 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38601.1 - 1.1e-09 38.1 0.8 6.4e-09 35.7 0.1 2.4 2 1 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain PALP PF00291.25 EGC38601.1 - 0.027 13.9 0.1 0.041 13.3 0.1 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme TrkA_N PF02254.18 EGC38601.1 - 0.074 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SPRY PF00622.28 EGC38602.1 - 4.8e-13 49.3 2.7 3.3e-08 33.6 0.0 3.5 3 0 0 3 3 3 2 SPRY domain PHD PF00628.29 EGC38602.1 - 0.00016 21.5 6.8 0.00043 20.1 6.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.6 EGC38602.1 - 0.012 15.7 1.9 0.036 14.2 1.9 1.8 1 0 0 1 1 1 0 PHD-zinc-finger like domain zf-HC5HC2H PF13771.6 EGC38602.1 - 0.018 15.3 2.6 0.062 13.6 2.6 2.0 1 0 0 1 1 1 0 PHD-like zinc-binding domain PHD_4 PF16866.5 EGC38602.1 - 0.43 10.7 3.7 1.7 8.8 3.7 2.1 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EGC38602.1 - 1.7 8.6 9.3 0.24 11.3 4.8 1.9 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) PseudoU_synth_2 PF00849.22 EGC38603.1 - 8e-32 110.5 1.6 2.1e-31 109.2 1.6 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase UCH PF00443.29 EGC38604.1 - 1.8e-44 152.2 38.9 1.8e-44 152.2 38.9 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC38604.1 - 2.7e-18 66.7 23.3 2.7e-18 66.7 23.3 2.4 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.19 EGC38604.1 - 9.1e-16 57.9 13.3 9.1e-16 57.9 13.3 3.4 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Serinc PF03348.15 EGC38604.1 - 0.0057 15.6 1.3 0.0057 15.6 1.3 1.7 2 0 0 2 2 2 1 Serine incorporator (Serinc) DUF3399 PF11879.8 EGC38604.1 - 0.023 15.0 0.2 0.023 15.0 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3399) GEN1_C PF18380.1 EGC38604.1 - 0.75 10.7 3.9 0.27 12.2 0.6 2.0 2 0 0 2 2 2 0 Holliday junction resolvase Gen1 C-terminal domain Connexin PF00029.19 EGC38604.1 - 3.2 7.4 9.0 0.53 10.0 0.5 3.0 3 0 0 3 3 3 0 Connexin PCI PF01399.27 EGC38605.1 - 5.5e-08 33.3 0.1 5.5e-08 33.3 0.1 3.0 4 1 0 4 4 4 1 PCI domain LRR_8 PF13855.6 EGC38606.1 - 6.4e-29 99.5 40.3 1.9e-10 40.3 6.0 5.6 4 0 0 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGC38606.1 - 2e-24 85.2 56.6 7.3e-07 29.4 8.4 8.2 4 1 3 8 8 8 7 Leucine Rich repeats (2 copies) Pkinase_Tyr PF07714.17 EGC38606.1 - 5.4e-23 81.6 0.0 1.1e-22 80.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 EGC38606.1 - 1.8e-13 50.6 4.8 2e-12 47.2 1.2 3.0 2 0 0 2 2 2 1 RhoGAP domain Pkinase PF00069.25 EGC38606.1 - 2.4e-13 50.0 0.0 5.6e-13 48.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RGS PF00615.19 EGC38606.1 - 9.6e-12 45.2 0.9 4.4e-11 43.1 0.9 2.2 1 0 0 1 1 1 1 Regulator of G protein signaling domain COR PF16095.5 EGC38606.1 - 4.5e-09 36.4 0.0 8.5e-06 25.7 0.0 3.4 3 1 0 3 3 3 2 C-terminal of Roc, COR, domain Kelch_3 PF13415.6 EGC38606.1 - 1.4e-07 31.6 1.0 0.029 14.7 0.1 4.6 4 0 0 4 4 3 2 Galactose oxidase, central domain Roc PF08477.13 EGC38606.1 - 2.5e-07 30.9 0.2 6.5e-07 29.6 0.2 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Kelch_6 PF13964.6 EGC38606.1 - 3.3e-06 27.2 3.2 0.022 15.1 0.1 3.9 3 0 0 3 3 3 2 Kelch motif Kelch_5 PF13854.6 EGC38606.1 - 3.9e-05 23.5 0.4 0.0091 16.0 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_1 PF01344.25 EGC38606.1 - 0.00016 21.2 0.5 0.077 12.6 0.0 2.7 2 0 0 2 2 2 2 Kelch motif Kelch_4 PF13418.6 EGC38606.1 - 0.00016 21.6 0.7 0.14 12.2 0.1 2.9 2 0 0 2 2 2 2 Galactose oxidase, central domain LRR_9 PF14580.6 EGC38606.1 - 0.00022 20.8 25.7 0.071 12.6 4.7 4.2 1 1 3 4 4 4 3 Leucine-rich repeat LRR_1 PF00560.33 EGC38606.1 - 0.0081 16.6 39.4 0.73 10.6 0.1 11.3 8 3 1 9 9 8 2 Leucine Rich Repeat Kelch_2 PF07646.15 EGC38606.1 - 0.01 15.8 2.0 0.068 13.2 0.2 3.1 2 1 0 2 2 2 0 Kelch motif LRR_6 PF13516.6 EGC38606.1 - 0.28 11.3 0.0 0.28 11.3 0.0 8.9 10 0 0 10 10 9 0 Leucine Rich repeat NLPC_P60 PF00877.19 EGC38607.1 - 2.9e-09 36.9 0.5 0.00042 20.3 1.2 2.5 2 0 0 2 2 2 2 NlpC/P60 family DUF1175 PF06672.11 EGC38607.1 - 0.069 12.8 0.0 0.42 10.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) Vps8 PF12816.7 EGC38608.1 - 4.6e-47 160.1 3.3 4.6e-47 160.1 3.3 4.3 4 1 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.20 EGC38608.1 - 2.8e-11 43.4 17.5 7.1e-07 29.2 1.4 3.8 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-C3H2C3 PF17122.5 EGC38608.1 - 2.3e-05 24.3 2.9 6.4e-05 22.9 2.9 1.8 1 0 0 1 1 1 1 Zinc-finger zf-rbx1 PF12678.7 EGC38608.1 - 0.0004 20.6 5.5 0.0011 19.2 5.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_5 PF14634.6 EGC38608.1 - 0.00045 20.1 5.9 0.0011 18.8 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC38608.1 - 0.00071 19.4 3.3 0.0022 17.8 3.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC38608.1 - 0.0035 17.0 0.4 0.0093 15.7 0.4 1.7 1 0 0 1 1 1 1 RING-like zinc finger zf-RING_2 PF13639.6 EGC38608.1 - 0.0055 17.0 6.5 0.016 15.5 6.5 1.9 1 0 0 1 1 1 1 Ring finger domain zf-RING_UBOX PF13445.6 EGC38608.1 - 0.031 14.3 2.9 0.092 12.8 2.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger ANAPC4_WD40 PF12894.7 EGC38608.1 - 0.14 12.5 0.0 12 6.3 0.0 3.1 2 1 1 3 3 3 0 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC38608.1 - 0.17 12.8 0.7 1.7 9.6 0.4 3.1 2 0 0 2 2 2 0 WD domain, G-beta repeat zf-C3HC4 PF00097.25 EGC38608.1 - 1.7 8.6 7.8 8.8 6.3 7.8 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pirin PF02678.16 EGC38609.1 - 1.2e-37 128.2 0.1 2e-37 127.4 0.1 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.13 EGC38609.1 - 5.3e-33 113.5 0.0 1.9e-31 108.5 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain KOW PF00467.29 EGC38609.1 - 0.028 14.4 0.1 0.2 11.6 0.0 2.5 2 0 0 2 2 2 0 KOW motif Cupin_2 PF07883.11 EGC38609.1 - 0.046 13.4 0.2 2.7 7.8 0.2 2.3 2 0 0 2 2 2 0 Cupin domain FNIP PF05725.12 EGC38610.1 - 5.6e-92 301.7 43.1 2.7e-15 56.3 1.8 7.8 3 2 2 8 8 8 8 FNIP Repeat Peptidase_C21 PF05381.12 EGC38610.1 - 0.076 13.4 0.9 36 4.8 0.0 3.5 3 0 0 3 3 3 0 Tymovirus endopeptidase LRR_1 PF00560.33 EGC38610.1 - 1.9 9.4 12.8 82 4.4 0.1 6.7 7 3 0 7 7 7 0 Leucine Rich Repeat DUF1769 PF08588.10 EGC38610.1 - 2.9 8.1 14.8 4.6 7.5 0.1 5.4 5 2 1 6 6 6 0 Protein of unknown function (DUF1769) THUMP PF02926.17 EGC38612.1 - 9.7e-11 42.0 1.1 9.7e-11 42.0 1.1 1.9 2 0 0 2 2 2 1 THUMP domain DNA_pol3_alpha PF07733.12 EGC38612.1 - 0.0008 19.1 0.8 0.0015 18.1 0.0 1.8 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha NTPase domain FNIP PF05725.12 EGC38613.1 - 2.4e-160 520.5 52.0 4e-15 55.7 2.0 13.1 7 1 4 14 14 14 14 FNIP Repeat zf-C2HC_2 PF13913.6 EGC38613.1 - 0.57 10.2 2.5 65 3.6 0.0 4.6 5 0 0 5 5 5 0 zinc-finger of a C2HC-type ketoacyl-synt PF00109.26 EGC38614.1 - 2.7e-61 207.4 0.0 4.5e-61 206.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.12 EGC38614.1 - 8.5e-45 152.9 0.0 2e-44 151.7 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC38614.1 - 9.6e-41 140.3 0.0 2.1e-40 139.2 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38614.1 - 6.2e-33 113.3 0.0 3e-32 111.1 0.0 2.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38614.1 - 3.1e-28 98.9 0.1 1.2e-25 90.5 0.1 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC38614.1 - 3.4e-23 82.3 0.0 5.2e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.12 EGC38614.1 - 8.9e-21 74.5 2.5 3.3e-20 72.7 0.0 3.5 3 0 0 3 3 1 1 Methyltransferase domain KAsynt_C_assoc PF16197.5 EGC38614.1 - 4.2e-16 59.4 0.4 1.8e-15 57.3 0.4 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38614.1 - 1.2e-09 39.3 0.0 3.6e-09 37.8 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC38614.1 - 1.6e-09 37.6 0.1 3.1e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGC38614.1 - 2.2e-05 24.7 0.0 8.4e-05 22.9 0.1 1.9 2 0 0 2 2 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGC38614.1 - 8.6e-05 23.1 0.0 0.00033 21.3 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain GDP_Man_Dehyd PF16363.5 EGC38614.1 - 9.3e-05 22.0 4.7 0.1 12.0 0.2 2.8 3 0 0 3 3 2 2 GDP-mannose 4,6 dehydratase ADH_N PF08240.12 EGC38614.1 - 0.00011 22.1 0.1 0.00026 20.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38614.1 - 0.0011 18.4 0.0 0.0024 17.3 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC38614.1 - 0.0023 17.8 0.0 0.007 16.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain 23S_rRNA_IVP PF05635.11 EGC38614.1 - 0.022 15.1 3.4 0.026 14.8 0.4 2.8 2 0 0 2 2 2 0 23S rRNA-intervening sequence protein adh_short PF00106.25 EGC38614.1 - 0.064 12.7 2.4 0.077 12.5 0.1 2.3 3 0 0 3 3 3 0 short chain dehydrogenase Methyltransf_31 PF13847.6 EGC38614.1 - 0.26 11.1 3.7 0.31 10.8 0.0 3.1 3 0 0 3 3 2 0 Methyltransferase domain Senescence PF06911.12 EGC38615.1 - 1.1e-28 100.7 5.6 3.4e-28 99.2 5.6 1.8 1 0 0 1 1 1 1 Senescence-associated protein PH PF00169.29 EGC38615.1 - 0.00029 21.3 0.0 0.00082 19.9 0.0 1.8 1 0 0 1 1 1 1 PH domain Cullin_binding PF03556.15 EGC38616.1 - 0.82 10.1 5.7 1.2 9.6 0.6 3.3 3 0 0 3 3 3 0 Cullin binding Pkinase PF00069.25 EGC38617.1 - 4.9e-72 242.5 0.0 6.3e-72 242.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38617.1 - 5.2e-35 121.0 0.1 1.1e-34 119.9 0.0 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC38617.1 - 5.4e-05 22.6 0.2 0.00011 21.7 0.1 1.7 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGC38617.1 - 0.0049 16.3 0.7 0.0079 15.6 0.7 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC38617.1 - 0.042 13.5 1.7 4.8 6.7 0.0 2.4 1 1 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Haspin_kinase PF12330.8 EGC38617.1 - 0.043 12.7 3.3 0.12 11.3 3.3 1.7 1 1 0 1 1 1 0 Haspin like kinase domain Pkinase_fungal PF17667.1 EGC38617.1 - 0.089 11.5 0.0 0.19 10.5 0.0 1.5 2 0 0 2 2 2 0 Fungal protein kinase APH PF01636.23 EGC38617.1 - 0.2 11.5 0.1 3.6 7.4 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1754 PF08555.10 EGC38618.1 - 1.5e-07 32.1 26.3 8e-07 29.8 22.3 2.6 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) DUF2058 PF09831.9 EGC38618.1 - 0.1 12.7 10.7 0.13 12.4 10.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) RapA_C PF12137.8 EGC38618.1 - 0.24 10.4 5.0 0.28 10.2 5.0 1.0 1 0 0 1 1 1 0 RNA polymerase recycling family C-terminal Menin PF05053.13 EGC38618.1 - 1.5 7.1 8.2 1.7 6.9 8.2 1.0 1 0 0 1 1 1 0 Menin HSP70 PF00012.20 EGC38618.1 - 3 5.9 10.3 3.4 5.7 10.3 1.0 1 0 0 1 1 1 0 Hsp70 protein Pox_Ag35 PF03286.14 EGC38618.1 - 3.7 7.3 17.0 5.2 6.8 17.0 1.3 1 1 0 1 1 1 0 Pox virus Ag35 surface protein ALMT PF11744.8 EGC38618.1 - 7.9 5.2 8.9 8.9 5.0 8.9 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter GCP_N_terminal PF17681.1 EGC38619.1 - 3.2e-75 253.6 1.9 3.2e-75 253.6 1.9 2.2 2 1 1 3 3 3 1 Gamma tubulin complex component N-terminal GCP_C_terminal PF04130.13 EGC38619.1 - 1.5e-72 244.7 12.0 1.5e-72 244.7 12.0 1.9 3 0 0 3 3 3 1 Gamma tubulin complex component C-terminal YL1 PF05764.13 EGC38619.1 - 0.0038 17.4 4.4 0.0038 17.4 4.4 2.0 2 0 0 2 2 2 1 YL1 nuclear protein DUF5432 PF17497.2 EGC38619.1 - 0.063 13.4 0.7 0.34 11.0 0.0 2.6 2 0 0 2 2 2 0 Family of unknown function (DUF5432) MutS_V PF00488.21 EGC38620.1 - 9.6e-63 211.6 0.1 1.7e-62 210.8 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGC38620.1 - 4.7e-26 92.2 0.4 4.7e-26 92.2 0.4 2.0 2 1 0 2 2 2 1 MutS domain III MutS_II PF05188.17 EGC38620.1 - 2.4e-06 27.9 0.1 9.1e-06 26.0 0.1 2.1 1 0 0 1 1 1 1 MutS domain II MutS_IV PF05190.18 EGC38620.1 - 7.7e-05 23.0 0.1 7.7e-05 23.0 0.1 3.0 3 0 0 3 3 3 1 MutS family domain IV AAA_27 PF13514.6 EGC38620.1 - 0.073 12.6 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2408 PF10303.9 EGC38620.1 - 0.7 10.5 5.0 0.17 12.4 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2408) Actin PF00022.19 EGC38622.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin WD40 PF00400.32 EGC38623.1 - 5.4e-20 71.4 6.5 0.00091 20.0 0.1 6.0 6 0 0 6 6 6 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38623.1 - 6.4e-06 26.4 0.0 0.071 13.4 0.2 4.2 1 1 2 3 3 3 2 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC38623.1 - 0.00069 19.6 0.7 0.013 15.3 0.3 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.8 EGC38623.1 - 0.0022 16.7 2.2 0.055 12.1 0.1 2.9 1 1 2 3 3 3 1 Nucleoporin Nup120/160 WD40_like PF17005.5 EGC38623.1 - 0.0026 17.2 0.0 0.0051 16.2 0.0 1.5 2 0 0 2 2 2 1 WD40-like domain ubiquitin PF00240.23 EGC38624.1 - 3.3e-18 65.2 0.0 7.1e-18 64.1 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC38624.1 - 3.2e-06 26.9 0.1 1.1e-05 25.1 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_4 PF18036.1 EGC38624.1 - 0.009 16.0 0.1 0.099 12.7 0.0 2.4 2 0 0 2 2 2 1 Ubiquitin-like domain DASH_Dad4 PF08650.10 EGC38624.1 - 0.67 10.0 8.0 1.3 9.1 0.0 3.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 PPTA PF01239.22 EGC38625.1 - 3e-46 153.9 13.2 8.4e-11 41.2 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PPTA PF01239.22 EGC38626.1 - 3e-46 153.9 13.2 8.4e-11 41.2 0.0 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat SIR2 PF02146.17 EGC38627.1 - 4.7e-59 199.3 0.0 8.7e-59 198.4 0.0 1.5 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.19 EGC38627.1 - 3.5e-18 65.7 12.8 3.5e-18 65.7 12.8 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Mucin PF01456.17 EGC38627.1 - 1.3e-05 25.2 11.6 1.3e-05 25.2 11.6 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein TPP_enzyme_M PF00205.22 EGC38627.1 - 0.00023 20.9 0.0 0.00073 19.3 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain FCP1_C PF09309.10 EGC38627.1 - 0.0083 16.0 1.1 0.014 15.3 1.1 1.3 1 0 0 1 1 1 1 FCP1, C-terminal DUF1729 PF08354.10 EGC38627.1 - 0.018 14.0 0.5 0.86 8.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1729) zf-C3HC4_3 PF13920.6 EGC38627.1 - 0.086 12.7 12.7 0.099 12.5 4.0 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) GET2 PF08690.10 EGC38627.1 - 0.26 10.9 4.7 0.38 10.4 4.7 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 Dicty_REP PF05086.12 EGC38627.1 - 0.33 8.9 12.7 0.44 8.5 12.7 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.11 EGC38627.1 - 0.67 8.1 22.0 1 7.5 22.0 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PP2C PF00481.21 EGC38628.1 - 5.5e-59 199.9 0.0 5.5e-59 199.9 0.0 3.7 3 1 2 5 5 5 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGC38628.1 - 0.02 14.5 0.0 0.065 12.9 0.0 1.8 1 0 0 1 1 1 0 Protein phosphatase 2C Sulf_transp PF04143.14 EGC38629.1 - 2.6e-53 181.6 13.1 3.4e-53 181.2 13.1 1.2 1 0 0 1 1 1 1 Sulphur transport Polysacc_synt_C PF14667.6 EGC38629.1 - 0.019 15.0 1.5 0.019 15.0 1.5 3.2 3 1 1 4 4 4 0 Polysaccharide biosynthesis C-terminal domain Consortin_C PF15281.6 EGC38629.1 - 0.05 13.6 0.1 0.09 12.8 0.1 1.3 1 0 0 1 1 1 0 Consortin C-terminus EGF_2 PF07974.13 EGC38630.1 - 0.1 13.0 10.9 0.25 11.7 10.9 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_1 PF00560.33 EGC38630.1 - 0.36 11.6 9.8 17 6.4 0.2 5.8 4 0 0 4 4 4 0 Leucine Rich Repeat Laminin_EGF PF00053.24 EGC38630.1 - 0.45 10.7 9.7 1.1 9.4 9.7 1.6 1 0 0 1 1 1 0 Laminin EGF domain FNIP PF05725.12 EGC38631.1 - 3e-61 203.4 88.1 1.6e-05 25.0 0.7 17.6 3 2 17 23 23 23 23 FNIP Repeat DUF2661 PF10860.8 EGC38631.1 - 3.6e-06 27.1 8.5 9.7 6.3 0.0 7.5 6 3 2 8 8 8 3 Protein of unknown function (DUF2661) DUF1563 PF07599.11 EGC38631.1 - 0.048 13.8 1.9 1.6e+02 2.5 0.1 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1563) Ribosomal_TL5_C PF14693.6 EGC38631.1 - 1.1 9.7 9.9 1.6e+02 2.7 0.0 7.2 10 0 0 10 10 10 0 Ribosomal protein TL5, C-terminal domain Methyltransf_11 PF08241.12 EGC38633.1 - 3.2e-21 75.8 0.1 5e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38633.1 - 2.3e-19 69.9 0.1 3.9e-19 69.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38633.1 - 2e-11 43.9 0.4 3.9e-11 43.0 0.3 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC38633.1 - 3.8e-11 43.6 0.1 7.4e-11 42.7 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC38633.1 - 7.8e-08 31.9 0.0 1.2e-07 31.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGC38633.1 - 1.4e-05 24.5 0.2 2.5e-05 23.7 0.2 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.6 EGC38633.1 - 1.8e-05 24.6 0.0 2.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC38633.1 - 0.00026 20.0 0.0 0.00062 18.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.17 EGC38633.1 - 0.00045 19.7 0.1 0.0025 17.3 0.1 2.0 1 1 0 1 1 1 1 Putative methyltransferase MTS PF05175.14 EGC38633.1 - 0.00082 19.0 0.0 0.002 17.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.20 EGC38633.1 - 0.00092 18.4 0.0 0.0013 17.8 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.15 EGC38633.1 - 0.0016 18.3 0.4 0.0078 16.1 0.4 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase MetW PF07021.12 EGC38633.1 - 0.0032 17.1 0.1 0.0046 16.6 0.1 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.10 EGC38633.1 - 0.026 14.1 0.2 0.078 12.5 0.1 1.8 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Synaptobrevin PF00957.21 EGC38633.1 - 0.03 14.1 0.0 0.057 13.2 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Methyltransf_PK PF05891.12 EGC38633.1 - 0.056 13.0 0.1 0.11 11.9 0.1 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Tetraspanin PF00335.20 EGC38634.1 - 8.4e-28 97.6 9.7 1e-27 97.4 9.7 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2976 PF11190.8 EGC38634.1 - 0.0097 15.7 1.6 0.0097 15.7 1.6 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF2976) FA_desaturase PF00487.24 EGC38634.1 - 0.059 13.2 0.1 0.088 12.6 0.1 1.3 1 0 0 1 1 1 0 Fatty acid desaturase DUF373 PF04123.13 EGC38634.1 - 0.085 12.3 5.9 0.018 14.5 2.5 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF4064 PF13273.6 EGC38634.1 - 0.65 10.3 16.2 23 5.3 15.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Pilin_N PF07790.11 EGC38634.1 - 0.95 10.4 4.6 3.2 8.7 0.3 2.5 2 0 0 2 2 2 0 Archaeal Type IV pilin, N-terminal DUF3784 PF12650.7 EGC38634.1 - 3.9 7.7 15.2 3 8.1 10.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) CRAL_TRIO PF00650.20 EGC38635.1 - 1.7e-15 57.1 0.0 3.4e-15 56.1 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.15 EGC38635.1 - 1.2e-07 31.8 0.3 1.2e-07 31.8 0.3 2.6 2 1 0 2 2 1 1 CRAL/TRIO, N-terminal domain RR_TM4-6 PF06459.12 EGC38635.1 - 0.036 13.9 19.9 0.053 13.3 19.9 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Neur_chan_memb PF02932.16 EGC38635.1 - 0.2 11.7 0.6 0.22 11.5 0.6 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FancD2 PF14631.6 EGC38635.1 - 0.2 9.0 12.3 0.25 8.7 12.3 1.0 1 0 0 1 1 1 0 Fanconi anaemia protein FancD2 nuclease DDHD PF02862.17 EGC38635.1 - 0.82 9.8 5.5 1.3 9.1 5.5 1.3 1 0 0 1 1 1 0 DDHD domain AAA_11 PF13086.6 EGC38635.1 - 1.3 8.7 10.3 1.9 8.2 10.3 1.3 1 0 0 1 1 1 0 AAA domain NARP1 PF12569.8 EGC38635.1 - 1.4 7.7 27.7 2.1 7.2 27.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Peroxin-13_N PF04088.13 EGC38635.1 - 1.7 8.9 5.0 3.7 7.8 5.0 1.5 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CPSF100_C PF13299.6 EGC38635.1 - 2.2 8.4 13.2 3.9 7.6 13.2 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal RNA_pol_Rpc4 PF05132.14 EGC38635.1 - 2.9 8.3 17.2 4.9 7.6 17.2 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 GAGA_bind PF06217.12 EGC38635.1 - 3 8.0 13.6 4.3 7.5 13.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF913 PF06025.12 EGC38635.1 - 3.3 6.6 7.7 5.2 5.9 7.7 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2828 PF11443.8 EGC38635.1 - 5.1 5.1 16.3 6.7 4.7 16.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2828) SpoIIP PF07454.11 EGC38635.1 - 5.4 6.4 17.9 9 5.7 17.9 1.3 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) ORC2 PF04084.14 EGC38636.1 - 8.1e-82 274.8 0.2 1e-81 274.4 0.2 1.1 1 0 0 1 1 1 1 Origin recognition complex subunit 2 Asparaginase_2 PF01112.18 EGC38637.1 - 1.4e-116 388.8 8.8 1.7e-116 388.5 8.8 1.0 1 0 0 1 1 1 1 Asparaginase Mt_ATP_synt PF15704.5 EGC38637.1 - 0.092 12.6 0.5 0.48 10.3 0.1 2.1 2 0 0 2 2 2 0 Mitochondrial ATP synthase subunit zf-RING_2 PF13639.6 EGC38639.1 - 1.6e-11 44.3 11.7 2.3e-11 43.8 9.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC38639.1 - 4e-08 33.0 10.3 7.9e-08 32.0 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC38639.1 - 2.1e-07 30.8 6.0 5.9e-07 29.4 6.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC38639.1 - 3.2e-07 30.1 6.2 6.9e-07 29.0 6.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38639.1 - 4.2e-07 29.7 9.7 1.4e-06 28.1 9.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38639.1 - 1.4e-06 28.5 16.4 3e-05 24.2 14.5 3.0 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_11 PF17123.5 EGC38639.1 - 6.5e-05 22.6 4.3 6.5e-05 22.6 4.3 2.1 2 0 0 2 2 2 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGC38639.1 - 0.0001 22.0 8.8 0.0001 22.0 8.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 Zn_ribbon_17 PF17120.5 EGC38639.1 - 0.0013 18.3 6.9 0.0013 18.3 6.9 2.3 2 0 0 2 2 2 1 Zinc-ribbon, C4HC2 type zf-RING_5 PF14634.6 EGC38639.1 - 0.0015 18.4 9.0 0.0015 18.4 9.0 2.3 2 1 0 2 2 2 1 zinc-RING finger domain Rad50_zn_hook PF04423.14 EGC38639.1 - 0.0058 16.5 0.0 0.019 14.8 0.0 1.8 1 0 0 1 1 1 1 Rad50 zinc hook motif CUE PF02845.16 EGC38639.1 - 0.0061 16.2 0.1 0.0061 16.2 0.1 2.2 2 0 0 2 2 2 1 CUE domain zf-C3HC4_4 PF15227.6 EGC38639.1 - 0.0096 16.1 5.3 0.022 14.9 5.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC38639.1 - 0.037 14.1 11.8 0.21 11.6 9.2 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.8 EGC38639.1 - 0.18 12.0 3.9 0.59 10.3 3.9 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.11 EGC38639.1 - 2.4 8.5 9.9 5.5 7.4 9.9 1.6 1 0 0 1 1 1 0 RING-like domain RINGv PF12906.7 EGC38639.1 - 2.8 8.1 9.4 6.8 6.9 9.4 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.6 EGC38639.1 - 7.2 6.5 7.1 14 5.5 6.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.25 EGC38640.1 - 9.3e-75 251.4 0.0 1.4e-74 250.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38640.1 - 7.2e-46 156.6 0.0 9.9e-46 156.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC38640.1 - 4.2e-07 29.6 0.0 7.3e-07 28.8 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC38640.1 - 0.0081 15.1 3.5 0.036 13.0 3.5 2.0 1 1 0 1 1 1 1 Haspin like kinase domain RIO1 PF01163.22 EGC38640.1 - 0.012 15.2 0.1 0.32 10.6 0.0 2.5 3 0 0 3 3 3 0 RIO1 family YrbL-PhoP_reg PF10707.9 EGC38640.1 - 0.023 14.2 0.1 0.057 12.9 0.1 1.7 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL FTA2 PF13095.6 EGC38640.1 - 0.051 13.2 0.1 8.2 6.0 0.0 2.4 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 MAP65_ASE1 PF03999.12 EGC38640.1 - 0.13 10.9 3.9 0.19 10.4 3.9 1.3 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) DUF1645 PF07816.11 EGC38640.1 - 0.23 12.0 7.5 0.37 11.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1645) Macoilin PF09726.9 EGC38640.1 - 2.2 6.8 5.4 2.5 6.5 5.4 1.1 1 0 0 1 1 1 0 Macoilin family SR-25 PF10500.9 EGC38640.1 - 7.6 6.1 15.6 11 5.5 15.6 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBFD_NFYB_HMF PF00808.23 EGC38642.1 - 6.4e-28 96.8 1.6 7.5e-28 96.6 1.6 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.24 EGC38642.1 - 6.8e-05 23.2 0.1 8.5e-05 22.9 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGC38642.1 - 0.00027 21.0 0.0 0.00032 20.8 0.0 1.1 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold Bromo_TP PF07524.13 EGC38642.1 - 0.00089 19.2 0.0 0.0012 18.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.16 EGC38642.1 - 0.017 15.2 0.1 0.022 14.8 0.1 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PIGA PF08288.12 EGC38643.1 - 1.1e-44 150.9 1.9 1.5e-44 150.5 0.7 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glyco_transf_4 PF13439.6 EGC38643.1 - 8.7e-28 97.4 0.0 1.3e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glycos_transf_1 PF00534.20 EGC38643.1 - 3.1e-27 95.2 0.1 6.3e-27 94.2 0.0 1.5 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC38643.1 - 1.1e-22 80.9 0.0 1.9e-22 80.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGC38643.1 - 6.1e-08 33.3 0.0 9.8e-08 32.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.6 EGC38643.1 - 8.5e-06 25.8 0.1 1.4e-05 25.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.6 EGC38643.1 - 0.024 15.0 0.0 0.088 13.2 0.0 2.0 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_transf_5 PF08323.11 EGC38643.1 - 0.085 12.5 0.0 0.21 11.2 0.0 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain Ndc80_HEC PF03801.13 EGC38644.1 - 1.1e-20 73.8 0.1 1.1e-20 73.8 0.1 3.9 4 0 0 4 4 4 2 HEC/Ndc80p family FNIP PF05725.12 EGC38647.1 - 1.1e-43 147.2 20.6 4.2e-13 49.2 0.7 6.1 3 2 2 6 6 6 6 FNIP Repeat zf-C2H2_jaz PF12171.8 EGC38647.1 - 3.6e-06 27.1 5.5 0.03 14.6 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.7 EGC38647.1 - 5.5e-05 23.4 5.8 0.01 16.1 2.1 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-met PF12874.7 EGC38647.1 - 0.00053 20.3 5.1 0.026 14.9 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type Atg14 PF10186.9 EGC38648.1 - 0.0018 17.4 5.3 0.0033 16.6 5.1 1.6 1 1 0 1 1 1 1 Vacuolar sorting 38 and autophagy-related subunit 14 FAA_hydrolase_N PF09298.11 EGC38648.1 - 0.067 13.4 0.6 0.53 10.5 0.1 2.3 1 1 0 2 2 2 0 Fumarylacetoacetase N-terminal CENP-F_leu_zip PF10473.9 EGC38648.1 - 0.11 12.5 21.8 0.1 12.6 5.9 2.7 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 APG6_N PF17675.1 EGC38648.1 - 0.38 11.3 15.4 0.15 12.5 4.1 2.4 2 0 0 2 2 2 0 Apg6 coiled-coil region Baculo_PEP_C PF04513.12 EGC38648.1 - 0.38 10.8 11.7 12 6.0 8.4 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Bacillus_HBL PF05791.11 EGC38648.1 - 0.5 10.2 21.4 0.19 11.5 4.1 2.3 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Spc7 PF08317.11 EGC38648.1 - 0.6 8.9 22.2 5.2 5.9 7.8 2.4 1 1 1 2 2 2 0 Spc7 kinetochore protein DUF4407 PF14362.6 EGC38648.1 - 1.2 8.4 9.1 0.2 10.9 3.7 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) TRAF_BIRC3_bd PF16673.5 EGC38648.1 - 1.3 8.9 8.5 6.4 6.6 0.6 3.2 2 1 0 3 3 3 0 TNF receptor-associated factor BIRC3 binding domain DUF724 PF05266.14 EGC38648.1 - 1.4 8.8 14.3 3.7 7.3 1.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ATG16 PF08614.11 EGC38648.1 - 4.2 7.5 16.0 10 6.3 3.5 2.7 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) Fib_alpha PF08702.10 EGC38648.1 - 5.5 7.2 20.7 0.11 12.7 8.4 2.7 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family HMMR_N PF15905.5 EGC38648.1 - 5.6 6.3 24.4 0.55 9.7 10.7 2.2 2 0 0 2 2 2 0 Hyaluronan mediated motility receptor N-terminal Exonuc_VII_L PF02601.15 EGC38648.1 - 9.1 5.8 10.1 45 3.5 10.1 1.9 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF4140 PF13600.6 EGC38648.1 - 9.3 6.8 8.8 1.3 9.6 1.2 2.9 1 1 2 3 3 3 0 N-terminal domain of unknown function (DUF4140) zf-C4H2 PF10146.9 EGC38648.1 - 9.6 6.4 16.3 1.6 9.0 9.2 2.5 1 1 0 2 2 2 0 Zinc finger-containing protein ThiF PF00899.21 EGC38649.1 - 3.4e-65 219.8 0.1 5e-65 219.3 0.1 1.2 1 0 0 1 1 1 1 ThiF family E2_bind PF08825.10 EGC38649.1 - 1.1e-21 76.8 0.0 1.7e-21 76.1 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.9 EGC38649.1 - 0.00042 20.3 0.5 0.023 14.6 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.6 EGC38649.1 - 0.0016 19.0 0.0 0.0036 17.9 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.20 EGC38649.1 - 0.0057 16.7 0.1 0.013 15.5 0.0 1.6 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DUF4974 PF16344.5 EGC38649.1 - 0.096 12.7 0.1 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4974) NAD_binding_4 PF07993.12 EGC38650.1 - 4.6e-32 111.2 0.0 8.1e-32 110.4 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.21 EGC38650.1 - 1.1e-24 87.6 0.0 1.7e-24 86.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Epimerase PF01370.21 EGC38650.1 - 5.8e-09 35.8 0.0 1.2e-08 34.7 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC38650.1 - 0.00058 19.0 0.1 0.001 18.1 0.1 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family zf-RING_2 PF13639.6 EGC38651.1 - 6.5e-10 39.2 12.5 1.1e-09 38.5 12.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38651.1 - 8.6e-08 31.9 10.3 1.4e-07 31.3 10.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38651.1 - 3.2e-07 30.1 12.9 5.4e-07 29.4 12.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38651.1 - 2.4e-06 27.3 15.9 5.1e-06 26.2 15.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38651.1 - 2.5e-06 27.7 9.1 2.5e-06 27.7 9.1 2.0 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38651.1 - 0.00037 20.4 8.9 0.00088 19.3 8.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger Caldesmon PF02029.15 EGC38651.1 - 0.0011 17.9 22.8 0.0011 17.9 22.8 1.9 2 0 0 2 2 2 1 Caldesmon zf-C3HC4_4 PF15227.6 EGC38651.1 - 0.0012 19.0 11.3 0.0028 17.8 11.2 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC38651.1 - 0.0026 17.6 10.2 0.0051 16.6 10.2 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC38651.1 - 0.0044 16.9 14.1 0.0078 16.2 14.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC38651.1 - 0.0092 16.0 4.7 0.021 14.9 4.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger YebO PF13974.6 EGC38651.1 - 0.033 14.3 0.3 0.033 14.3 0.3 3.9 4 0 0 4 4 3 0 YebO-like protein zf-RING_4 PF14570.6 EGC38651.1 - 0.068 13.0 12.9 0.17 11.7 12.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.6 EGC38651.1 - 0.18 11.7 5.5 0.38 10.6 5.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_10 PF16685.5 EGC38651.1 - 0.39 10.9 7.5 1 9.5 7.5 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 RELT PF12606.8 EGC38651.1 - 0.96 8.5 3.3 2.5 7.2 3.3 1.7 1 0 0 1 1 1 0 Tumour necrosis factor receptor superfamily member 19 DZR PF12773.7 EGC38651.1 - 1.4 9.0 8.1 3 7.9 8.1 1.5 1 0 0 1 1 1 0 Double zinc ribbon Phage_TAC_4 PF08748.11 EGC38651.1 - 7.1 7.0 16.5 4.8 7.5 13.2 2.4 2 1 0 2 2 2 0 Phage tail assembly chaperone Methyltransf_11 PF08241.12 EGC38652.1 - 3.3e-09 37.3 0.0 6.2e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38652.1 - 1.5e-06 28.8 0.0 2.8e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC38652.1 - 0.00042 19.7 0.0 0.00055 19.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DUF2861 PF11060.8 EGC38652.1 - 0.051 13.2 0.2 2.7 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2861) Tim44 PF04280.15 EGC38653.1 - 0.013 15.6 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 Tim44-like domain DinB PF05163.12 EGC38653.1 - 0.014 15.3 1.0 0.036 14.0 1.0 1.6 1 0 0 1 1 1 0 DinB family 7tm_1 PF00001.21 EGC38654.1 - 2.7e-06 26.9 17.5 0.00036 20.0 6.5 2.8 1 1 2 3 3 3 2 7 transmembrane receptor (rhodopsin family) TMIE PF16038.5 EGC38654.1 - 0.055 13.3 0.0 0.25 11.2 0.0 2.1 1 0 0 1 1 1 0 TMIE protein CarD_CdnL_TRCF PF02559.16 EGC38655.1 - 0.22 12.3 3.8 0.29 11.9 1.1 2.7 2 1 0 2 2 2 0 CarD-like/TRCF domain DUF3439 PF11921.8 EGC38655.1 - 0.89 9.5 14.4 2 8.4 14.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SH3_1 PF00018.28 EGC38656.1 - 6.3e-14 51.3 0.2 1.4e-13 50.3 0.2 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC38656.1 - 5.4e-13 48.6 0.2 1e-12 47.7 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC38656.1 - 6.4e-10 38.6 0.0 1.1e-09 37.8 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_C33 PF05412.12 EGC38656.1 - 0.16 12.0 0.6 0.27 11.3 0.6 1.3 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase DUF4686 PF15742.5 EGC38657.1 - 0.001 18.3 2.5 0.001 18.3 2.5 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4686) MCCD1 PF15707.5 EGC38657.1 - 0.13 12.8 0.1 0.13 12.8 0.1 2.2 3 0 0 3 3 3 0 Mitochondrial coiled-coil domain protein 1 DUF4521 PF15021.6 EGC38657.1 - 0.57 10.1 10.1 0.51 10.2 6.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4521) Clat_adaptor_s PF01217.20 EGC38658.1 - 1.1e-47 161.6 5.2 1.2e-47 161.4 5.2 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.25 EGC38659.1 - 5.6e-67 225.9 0.1 1.1e-66 225.0 0.1 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38659.1 - 2.1e-40 138.6 0.0 3.2e-40 138.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC38659.1 - 2.6e-08 33.6 0.0 5.8e-08 32.4 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Kdo PF06293.14 EGC38659.1 - 0.012 15.0 0.0 0.02 14.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family FTA2 PF13095.6 EGC38659.1 - 0.04 13.5 1.7 4.2 6.9 0.1 2.8 1 1 1 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 Rpp20 PF12328.8 EGC38659.1 - 0.057 13.4 0.1 0.66 9.9 0.0 2.5 2 0 0 2 2 2 0 Rpp20 subunit of nuclear RNase MRP and P APH PF01636.23 EGC38659.1 - 0.15 11.9 0.0 1.8 8.4 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_22 PF03901.17 EGC38660.1 - 1.3e-81 275.0 39.5 1.7e-81 274.6 39.5 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1697 PF08002.11 EGC38661.1 - 7.6e-13 49.1 0.0 9.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Vps35 PF03635.17 EGC38661.1 - 0.044 12.3 0.1 0.048 12.2 0.1 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 p450 PF00067.22 EGC38662.1 - 5.8e-56 190.1 0.4 2.8e-55 187.9 0.4 1.8 1 1 0 1 1 1 1 Cytochrome P450 RsmF_methylt_CI PF17126.5 EGC38662.1 - 0.042 13.9 0.0 0.08 13.0 0.0 1.4 1 0 0 1 1 1 0 RsmF rRNA methyltransferase first C-terminal domain EnY2 PF10163.9 EGC38662.1 - 0.12 12.7 0.7 5.8 7.4 0.0 2.9 3 0 0 3 3 3 0 Transcription factor e(y)2 Acyl-CoA_dh_1 PF00441.24 EGC38663.1 - 4.5e-25 88.6 0.1 7.1e-25 88.0 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.19 EGC38663.1 - 5.5e-15 55.3 0.0 1.1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC38663.1 - 2.1e-05 24.8 0.0 3.6e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGC38663.1 - 0.033 14.9 0.0 0.073 13.7 0.0 1.5 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain ubiquitin PF00240.23 EGC38664.1 - 3.4e-12 45.9 0.1 5.4e-12 45.3 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin family DUF2407_C PF13373.6 EGC38664.1 - 3.5e-06 27.2 0.0 5e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD PF11976.8 EGC38664.1 - 0.00013 21.7 0.1 0.00024 20.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.6 EGC38664.1 - 0.001 19.1 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC38664.1 - 0.0086 16.6 0.1 0.019 15.5 0.0 1.5 1 1 0 1 1 1 1 DUF2407 ubiquitin-like domain BolA PF01722.18 EGC38666.1 - 3.5e-28 97.7 0.1 4.2e-28 97.4 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein NTPase_I-T PF01931.18 EGC38667.1 - 6.9e-52 175.5 0.0 7.8e-52 175.3 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 PRP38 PF03371.15 EGC38668.1 - 5.5e-45 153.3 1.5 7.6e-45 152.9 1.5 1.2 1 0 0 1 1 1 1 PRP38 family MAM33 PF02330.16 EGC38669.1 - 1.1e-14 54.9 28.0 2.5e-07 30.9 22.1 3.1 2 1 0 2 2 2 2 Mitochondrial glycoprotein FmiP_Thoc5 PF09766.9 EGC38669.1 - 0.00021 20.7 9.9 0.00035 20.0 9.9 1.3 1 0 0 1 1 1 1 Fms-interacting protein/Thoc5 Mpp10 PF04006.12 EGC38669.1 - 0.00093 17.8 19.0 0.0011 17.5 19.0 1.1 1 0 0 1 1 1 1 Mpp10 protein RNA_pol_3_Rpc31 PF11705.8 EGC38669.1 - 0.0017 18.7 21.1 0.0032 17.8 21.1 1.5 1 0 0 1 1 1 1 DNA-directed RNA polymerase III subunit Rpc31 PPP4R2 PF09184.11 EGC38669.1 - 0.003 17.2 18.7 0.0042 16.7 18.7 1.1 1 0 0 1 1 1 1 PPP4R2 SpoIIP PF07454.11 EGC38669.1 - 0.0045 16.5 6.5 0.0069 15.9 6.5 1.3 1 0 0 1 1 1 1 Stage II sporulation protein P (SpoIIP) DDHD PF02862.17 EGC38669.1 - 0.0055 16.9 0.4 0.0062 16.7 0.4 1.3 1 0 0 1 1 1 1 DDHD domain Tim54 PF11711.8 EGC38669.1 - 0.013 14.4 8.7 0.024 13.4 8.7 1.4 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Nop14 PF04147.12 EGC38669.1 - 0.013 13.8 24.3 0.018 13.3 24.3 1.2 1 0 0 1 1 1 0 Nop14-like family RR_TM4-6 PF06459.12 EGC38669.1 - 0.014 15.3 10.8 0.017 15.0 10.8 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 SDA1 PF05285.12 EGC38669.1 - 0.019 14.4 21.1 0.027 13.9 21.1 1.2 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.17 EGC38669.1 - 0.039 12.7 5.7 0.042 12.6 5.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC38669.1 - 0.049 11.9 17.8 0.066 11.5 17.8 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.12 EGC38669.1 - 0.077 12.4 25.5 0.12 11.7 25.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT ORC_WH_C PF18137.1 EGC38669.1 - 0.081 13.0 9.1 0.13 12.3 9.1 1.4 1 0 0 1 1 1 0 Origin recognition complex winged helix C-terminal RNA_pol_Rpc4 PF05132.14 EGC38669.1 - 0.096 13.1 6.0 0.16 12.4 6.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 RPA43_OB PF17875.1 EGC38669.1 - 0.17 12.5 6.1 0.38 11.4 6.1 1.6 1 0 0 1 1 1 0 RPA43 OB domain in RNA Pol I RRN3 PF05327.11 EGC38669.1 - 0.18 10.3 12.7 0.22 10.0 12.7 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF913 PF06025.12 EGC38669.1 - 0.23 10.4 5.6 0.29 10.0 5.6 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF5523 PF17661.1 EGC38669.1 - 0.32 10.6 23.2 0.49 10.0 23.2 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5523) FYDLN_acid PF09538.10 EGC38669.1 - 0.36 11.5 16.1 0.66 10.7 16.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (FYDLN_acid) CTU2 PF10288.9 EGC38669.1 - 0.41 10.9 4.3 1 9.6 4.3 1.7 1 0 0 1 1 1 0 Cytoplasmic tRNA 2-thiolation protein 2 DNA_pol_phi PF04931.13 EGC38669.1 - 0.57 8.2 33.4 0.82 7.7 33.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi CPSF100_C PF13299.6 EGC38669.1 - 0.81 9.8 10.3 1.5 9.0 10.3 1.4 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal TERB2 PF15101.6 EGC38669.1 - 1.5 8.8 6.9 1.8 8.5 3.3 2.3 3 0 0 3 3 3 0 Telomere-associated protein TERB2 DUF4746 PF15928.5 EGC38669.1 - 1.7 8.0 19.5 2.8 7.3 19.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4746) Hid1 PF12722.7 EGC38669.1 - 1.8 6.6 6.6 2.3 6.2 6.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein RP-C_C PF11800.8 EGC38669.1 - 2.1 8.4 7.5 3.5 7.7 7.5 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Connexin PF00029.19 EGC38669.1 - 4.1 7.1 8.3 6.3 6.5 8.3 1.2 1 0 0 1 1 1 0 Connexin PPL5 PF18168.1 EGC38669.1 - 4.1 6.6 7.1 7.4 5.8 7.1 1.4 1 0 0 1 1 1 0 Prim-pol family 5 Smg4_UPF3 PF03467.15 EGC38669.1 - 4.2 7.4 14.0 7.2 6.6 14.0 1.4 1 0 0 1 1 1 0 Smg-4/UPF3 family Sporozoite_P67 PF05642.11 EGC38669.1 - 4.4 5.3 10.2 5.9 4.8 10.2 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ALMT PF11744.8 EGC38669.1 - 5.6 5.7 6.0 7.1 5.3 6.0 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Paf1 PF03985.13 EGC38669.1 - 5.7 5.8 29.7 9.2 5.1 29.7 1.2 1 0 0 1 1 1 0 Paf1 Serinc PF03348.15 EGC38669.1 - 6 5.7 5.9 8.3 5.2 5.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MRNIP PF15749.5 EGC38669.1 - 6.7 7.5 13.7 5.5 7.8 11.4 2.0 2 0 0 2 2 2 0 MRN-interacting protein Sec62 PF03839.16 EGC38669.1 - 9.9 5.6 6.8 17 4.9 6.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF489 PF04356.12 EGC38670.1 - 0.00057 20.0 0.6 0.00076 19.5 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF489) HMMR_N PF15905.5 EGC38670.1 - 0.0025 17.3 5.0 0.0028 17.2 5.0 1.2 1 0 0 1 1 1 1 Hyaluronan mediated motility receptor N-terminal PTS_EIIA_2 PF00359.22 EGC38670.1 - 0.012 15.5 0.3 0.021 14.7 0.3 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF641 PF04859.12 EGC38670.1 - 0.016 15.6 1.0 0.03 14.7 1.0 1.5 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) Sec8_exocyst PF04048.14 EGC38670.1 - 0.018 14.9 2.4 0.029 14.3 2.4 1.3 1 0 0 1 1 1 0 Sec8 exocyst complex component specific domain AATF-Che1 PF13339.6 EGC38670.1 - 0.036 14.8 1.5 0.046 14.4 1.5 1.2 1 0 0 1 1 1 0 Apoptosis antagonizing transcription factor Exonuc_VII_L PF02601.15 EGC38670.1 - 0.051 13.2 2.6 0.054 13.1 2.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit APC_u15 PF16636.5 EGC38670.1 - 0.085 13.3 1.0 0.28 11.7 0.1 2.0 2 0 0 2 2 2 0 Unstructured region on APC between APC_crr regions 5 and 6 NAPRTase_N PF17767.1 EGC38670.1 - 0.11 12.8 2.6 0.16 12.4 2.6 1.3 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) N-terminal domain FapA PF03961.13 EGC38670.1 - 0.23 10.0 7.4 0.25 9.9 7.4 1.1 1 0 0 1 1 1 0 Flagellar Assembly Protein A TACC_C PF05010.14 EGC38670.1 - 0.25 11.1 10.2 0.058 13.2 3.9 2.1 1 1 1 2 2 2 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal LRRFIP PF09738.9 EGC38670.1 - 0.27 10.7 8.5 0.29 10.6 2.6 2.0 1 1 0 2 2 2 0 LRRFIP family RPW8 PF05659.11 EGC38670.1 - 0.29 10.8 5.5 0.42 10.3 5.5 1.2 1 0 0 1 1 1 0 Arabidopsis broad-spectrum mildew resistance protein RPW8 Fib_alpha PF08702.10 EGC38670.1 - 0.62 10.3 9.2 0.12 12.5 4.6 2.0 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family DUF2714 PF10896.8 EGC38670.1 - 0.68 10.0 12.7 0.24 11.4 3.2 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2714) DUF3972 PF13118.6 EGC38670.1 - 1 9.8 9.3 1.9 8.9 4.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3972) Troponin PF00992.20 EGC38670.1 - 1.8 8.9 9.4 0.24 11.7 4.6 1.7 1 1 0 2 2 2 0 Troponin DUF16 PF01519.16 EGC38670.1 - 6 7.4 11.7 0.21 12.1 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function DUF16 Vps51 PF08700.11 EGC38671.1 - 4.5e-26 90.7 0.7 4.5e-26 90.7 0.7 3.2 3 0 0 3 3 3 1 Vps51/Vps67 Sec5 PF15469.6 EGC38671.1 - 1.4e-16 60.9 8.5 1.4e-16 60.9 8.5 3.4 2 1 0 3 3 3 1 Exocyst complex component Sec5 Dor1 PF04124.12 EGC38671.1 - 2.1e-08 33.3 12.3 2.1e-08 33.3 12.3 2.3 3 1 0 3 3 3 1 Dor1-like family Vps54_N PF10475.9 EGC38671.1 - 2.5e-05 23.7 9.0 2.5e-05 23.7 9.0 2.3 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex COG2 PF06148.11 EGC38671.1 - 0.0014 18.7 10.4 0.013 15.5 0.1 3.8 4 0 0 4 4 4 2 COG (conserved oligomeric Golgi) complex component, COG2 Exonuc_VII_S PF02609.16 EGC38671.1 - 0.027 14.5 0.5 0.23 11.6 0.2 2.7 2 0 0 2 2 2 0 Exonuclease VII small subunit Cyclin_N PF00134.23 EGC38672.1 - 0.0003 20.5 0.2 0.0003 20.5 0.2 3.5 4 1 0 4 4 4 1 Cyclin, N-terminal domain Phosducin PF02114.16 EGC38672.1 - 0.0088 15.0 0.9 0.0088 15.0 0.9 2.4 1 1 0 2 2 2 1 Phosducin DUF5051 PF16473.5 EGC38673.1 - 9.6e-07 28.9 0.0 1.5e-05 25.0 0.0 2.5 2 0 0 2 2 2 1 3' exoribonuclease, RNase T-like TUSC2 PF15000.6 EGC38673.1 - 0.025 14.8 0.4 0.025 14.8 0.4 3.8 3 1 1 4 4 4 0 Tumour suppressor candidate 2 CReP_N PF10472.9 EGC38673.1 - 0.05 12.5 3.4 0.093 11.6 3.4 1.3 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor Ctr PF04145.15 EGC38675.1 - 3.1e-23 83.1 12.0 8.4e-22 78.4 12.0 2.1 1 1 0 1 1 1 1 Ctr copper transporter family DUF92 PF01940.16 EGC38676.1 - 7.8e-75 251.3 5.1 9.3e-75 251.1 5.1 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 DUF5326 PF17260.2 EGC38676.1 - 0.96 9.6 3.3 0.53 10.5 0.2 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF5326) DDDD PF10161.9 EGC38676.1 - 1.1 9.1 2.8 4.1 7.2 0.4 2.6 2 0 0 2 2 2 0 Putative mitochondrial precursor protein Colicin_V PF02674.16 EGC38676.1 - 1.3 9.0 13.5 4.4 7.3 2.6 3.0 2 1 0 2 2 2 0 Colicin V production protein PRMT5 PF05185.16 EGC38677.1 - 7.5e-72 240.8 0.1 1.2e-71 240.1 0.1 1.3 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PRMT5_TIM PF17285.2 EGC38677.1 - 5e-68 229.1 3.0 7.3e-68 228.5 3.0 1.2 1 0 0 1 1 1 1 PRMT5 TIM barrel domain PRMT5_C PF17286.2 EGC38677.1 - 1.8e-54 184.3 10.1 1.2e-53 181.6 7.7 2.4 2 0 0 2 2 2 1 PRMT5 oligomerisation domain Met_10 PF02475.16 EGC38677.1 - 0.00022 21.0 0.0 0.00037 20.3 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Ribosomal_60s PF00428.19 EGC38678.1 - 4e-20 72.2 8.6 5e-20 71.9 8.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Cytomega_UL84 PF06284.11 EGC38678.1 - 0.096 11.1 0.6 0.11 11.0 0.6 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein DUF3824 PF12868.7 EGC38678.1 - 0.1 13.3 3.4 0.14 12.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) EIIBC-GUT_N PF03612.14 EGC38678.1 - 0.13 12.0 0.1 0.15 11.8 0.1 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3235 PF11574.8 EGC38678.1 - 1.5 9.7 13.4 5.9 7.8 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3235) Gln-synt_C PF00120.24 EGC38679.1 - 5.9e-91 305.0 0.0 6.8e-91 304.8 0.0 1.0 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N_2 PF16952.5 EGC38679.1 - 3.1e-05 23.8 0.0 5.5e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 Glutamine synthetase N-terminal domain Peptidase_M3 PF01432.20 EGC38680.1 - 3.6e-86 290.2 0.1 5.1e-86 289.8 0.1 1.2 1 0 0 1 1 1 1 Peptidase family M3 DUF4043 PF13252.6 EGC38680.1 - 0.099 11.7 0.0 0.18 10.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4043) OTU PF02338.19 EGC38682.1 - 1.1e-11 45.4 0.0 1.1e-11 45.4 0.0 3.5 2 1 0 2 2 2 1 OTU-like cysteine protease DUF3645 PF12359.8 EGC38682.1 - 0.037 13.4 0.1 9 5.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) TFIIA PF03153.13 EGC38682.1 - 0.67 9.9 49.9 1.3 9.0 49.9 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Band_3_cyto PF07565.13 EGC38682.1 - 2.1 8.1 19.5 3.3 7.4 19.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAP_RNA-bind PF04926.15 EGC38684.1 - 0.023 14.3 2.4 0.041 13.5 2.4 1.3 1 0 0 1 1 1 0 Poly(A) polymerase predicted RNA binding domain ETRAMP PF09716.10 EGC38684.1 - 0.67 10.0 10.5 1.5 9.0 10.5 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) OTU PF02338.19 EGC38685.1 - 3.5e-12 46.9 0.0 3.5e-12 46.9 0.0 3.2 2 1 0 2 2 2 1 OTU-like cysteine protease Neur_chan_memb PF02932.16 EGC38685.1 - 0.013 15.6 15.3 0.021 14.9 15.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Hid1 PF12722.7 EGC38685.1 - 0.62 8.1 21.3 0.78 7.8 21.3 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein PAT1 PF09770.9 EGC38685.1 - 6.6 4.9 47.9 9 4.4 47.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C1 PF00112.23 EGC38686.1 - 5.2e-78 262.1 3.8 7e-78 261.7 3.8 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC38686.1 - 1.9e-14 53.8 3.7 3.1e-14 53.1 3.7 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC38686.1 - 0.00014 20.8 2.3 0.099 11.4 0.7 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Serglycin PF04360.12 EGC38686.1 - 0.0058 16.6 6.0 0.014 15.3 6.0 1.6 1 0 0 1 1 1 1 Serglycin TACC_C PF05010.14 EGC38687.1 - 0.00079 19.3 3.1 0.00092 19.0 3.1 1.1 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Mei5 PF10376.9 EGC38687.1 - 0.0084 16.0 9.3 0.011 15.7 9.3 1.0 1 0 0 1 1 1 1 Double-strand recombination repair protein DUF2524 PF10732.9 EGC38687.1 - 0.022 15.1 0.9 0.047 14.0 0.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) DUF2203 PF09969.9 EGC38687.1 - 0.34 11.6 2.0 0.58 10.9 2.1 1.3 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) TACC_C PF05010.14 EGC38688.1 - 9.3e-05 22.3 24.4 0.0014 18.5 7.9 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC), C-terminal CENP-F_leu_zip PF10473.9 EGC38688.1 - 0.0049 16.9 4.9 0.0049 16.9 4.9 2.9 1 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Toprim_Crpt PF13342.6 EGC38688.1 - 0.0052 16.7 0.7 0.097 12.7 0.3 2.8 2 0 0 2 2 2 1 C-terminal repeat of topoisomerase Gal4_dimer PF03902.13 EGC38688.1 - 0.0058 16.8 5.8 0.05 13.8 0.4 3.0 2 1 0 2 2 2 1 Gal4-like dimerisation domain EMC3_TMCO1 PF01956.16 EGC38688.1 - 0.013 15.2 0.8 0.013 15.2 0.8 2.7 1 1 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like DUF4199 PF13858.6 EGC38688.1 - 0.12 12.8 0.1 0.12 12.8 0.1 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) Spc7 PF08317.11 EGC38688.1 - 1.1 8.1 26.0 1.8 7.4 25.6 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DUF948 PF06103.11 EGC38688.1 - 3.7 7.9 7.3 7.2 6.9 2.0 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) FNIP PF05725.12 EGC38689.1 - 9.4e-50 166.5 55.4 1.5e-09 37.9 0.2 9.9 3 3 9 12 12 12 12 FNIP Repeat C1_1 PF00130.22 EGC38690.1 - 2.7e-13 49.6 31.7 3.1e-07 30.2 10.8 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) C1_2 PF03107.16 EGC38690.1 - 0.00067 19.9 25.3 0.005 17.1 10.8 2.8 2 0 0 2 2 2 2 C1 domain Thioredoxin_4 PF13462.6 EGC38690.1 - 0.013 15.6 0.2 0.013 15.6 0.2 2.7 2 0 0 2 2 2 0 Thioredoxin DNA_pol_B PF00136.21 EGC38691.1 - 9.4e-136 453.2 0.1 1.3e-135 452.7 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.19 EGC38691.1 - 2.5e-83 280.0 3.8 4.8e-83 279.1 3.8 1.5 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.6 EGC38691.1 - 2.4e-17 63.2 9.7 5.1e-17 62.1 9.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.6 EGC38691.1 - 0.0081 16.2 0.1 0.031 14.3 0.1 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_2 PF03175.13 EGC38691.1 - 0.01 14.8 0.0 0.017 14.0 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase type B, organellar and viral TIP120 PF08623.10 EGC38692.1 - 2.1e-58 196.8 23.3 1.2e-56 191.1 0.3 6.5 8 2 0 8 8 8 3 TATA-binding protein interacting (TIP20) HEAT PF02985.22 EGC38692.1 - 7.5e-14 50.7 20.4 2.5 8.6 0.0 13.1 15 0 0 15 15 12 4 HEAT repeat HEAT_2 PF13646.6 EGC38692.1 - 2.8e-13 50.1 0.2 1.5 9.3 0.0 8.6 7 3 3 10 10 9 5 HEAT repeats HEAT_EZ PF13513.6 EGC38692.1 - 2.4e-09 37.5 0.1 44 4.7 0.0 9.5 8 2 2 10 10 9 0 HEAT-like repeat Cnd1 PF12717.7 EGC38692.1 - 1.2e-05 25.5 47.1 0.0085 16.1 0.1 9.5 4 3 4 9 9 9 4 non-SMC mitotic condensation complex subunit 1 ParcG PF10274.9 EGC38692.1 - 0.00013 22.2 19.2 0.06 13.5 0.0 7.0 7 1 0 7 7 7 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.7 EGC38692.1 - 0.00026 21.5 13.9 47 4.7 0.0 9.0 9 2 2 11 11 11 0 Vacuolar 14 Fab1-binding region UME PF08064.13 EGC38692.1 - 0.00033 20.5 10.6 0.34 10.8 0.0 6.7 5 3 3 8 8 8 1 UME (NUC010) domain MMS19_N PF14500.6 EGC38692.1 - 0.00035 20.2 10.9 0.014 14.9 0.0 6.2 4 2 3 7 7 7 1 Dos2-interacting transcription regulator of RNA-Pol-II RTP1_C1 PF10363.9 EGC38692.1 - 0.0015 18.7 5.7 1.9 8.7 0.1 6.3 6 1 1 7 7 6 1 Required for nuclear transport of RNA pol II C-terminus 1 DUF3385 PF11865.8 EGC38692.1 - 0.0022 17.9 5.0 0.36 10.7 0.0 5.2 4 2 0 4 4 4 1 Domain of unknown function (DUF3385) DUF3437 PF11919.8 EGC38692.1 - 0.0043 16.9 0.2 11 6.0 0.1 5.1 3 2 2 5 5 5 1 Domain of unknown function (DUF3437) CLASP_N PF12348.8 EGC38692.1 - 0.0058 16.2 1.0 0.0058 16.2 1.0 6.7 5 2 1 7 7 7 1 CLASP N terminal DNA_pol_phi PF04931.13 EGC38692.1 - 0.58 8.2 18.5 0.062 11.4 5.4 2.9 3 0 0 3 3 3 0 DNA polymerase phi DUF4746 PF15928.5 EGC38692.1 - 2.4 7.5 6.6 0.71 9.2 2.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4746) tRNA-synt_His PF13393.6 EGC38693.1 - 3.1e-48 164.6 0.0 3.9e-48 164.3 0.0 1.1 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon PF03129.20 EGC38693.1 - 1.4e-15 57.2 0.5 8.9e-15 54.6 0.1 2.3 2 0 0 2 2 2 1 Anticodon binding domain HGTP_anticodon2 PF12745.7 EGC38693.1 - 1.2e-05 25.0 0.1 1.2e-05 25.0 0.1 1.5 2 0 0 2 2 2 1 Anticodon binding domain of tRNAs tRNA-synt_2 PF00152.20 EGC38693.1 - 7.2e-05 22.0 0.1 0.00086 18.5 0.1 2.3 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA-synt_2b PF00587.25 EGC38693.1 - 0.0012 18.8 0.0 0.0088 16.0 0.0 2.4 1 1 1 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HHH_8 PF14716.6 EGC38693.1 - 0.0029 17.9 0.1 0.011 16.1 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain PB1 PF00564.24 EGC38694.1 - 5.4e-07 29.5 0.1 1e-06 28.6 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TLD PF07534.16 EGC38695.1 - 4.2e-28 98.3 1.1 4.2e-28 98.3 1.1 2.3 2 1 1 3 3 3 1 TLD RabGAP-TBC PF00566.18 EGC38695.1 - 6.8e-25 88.0 1.6 6.8e-25 88.0 1.6 2.4 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3439 PF11921.8 EGC38695.1 - 0.75 9.8 7.1 1.6 8.7 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Macoilin PF09726.9 EGC38695.1 - 7 5.1 20.6 12 4.3 20.6 1.3 1 0 0 1 1 1 0 Macoilin family RNA_pol_Rpb2_6 PF00562.28 EGC38696.1 - 1.5e-119 399.5 0.0 3.3e-119 398.4 0.0 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.15 EGC38696.1 - 1.7e-52 177.9 0.2 2.9e-52 177.1 0.2 1.4 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.20 EGC38696.1 - 1.6e-32 111.7 0.2 5.3e-32 110.1 0.2 2.0 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.13 EGC38696.1 - 2.2e-25 88.7 0.5 8.1e-25 86.9 0.5 2.1 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_2 PF04561.14 EGC38696.1 - 2.3e-24 86.1 0.3 2.3e-24 86.1 0.3 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_3 PF04565.16 EGC38696.1 - 6.4e-16 58.3 0.3 4.7e-13 49.1 0.0 2.8 2 0 0 2 2 2 2 RNA polymerase Rpb2, domain 3 Intein_splicing PF14890.6 EGC38696.1 - 6.1e-10 39.2 5.3 1.7e-09 37.8 5.3 1.7 1 0 0 1 1 1 1 Intein splicing domain RNA_pol_Rpb2_5 PF04567.17 EGC38696.1 - 4.8e-08 33.4 2.5 2.1e-07 31.4 2.5 2.2 1 1 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hint PF01079.20 EGC38696.1 - 5.1e-05 22.9 0.0 9.8e-05 22.0 0.0 1.4 1 0 0 1 1 1 1 Hint module FlbD PF06289.11 EGC38696.1 - 0.35 10.5 1.7 4.4 7.0 0.1 3.3 3 0 0 3 3 3 0 Flagellar and Swarming motility proteins HABP4_PAI-RBP1 PF04774.15 EGC38697.1 - 7.8e-08 33.2 9.6 7.8e-08 33.2 9.6 4.3 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Neugrin PF06413.11 EGC38698.1 - 5.9e-10 39.5 1.3 5.9e-10 39.5 1.3 2.9 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.7 EGC38698.1 - 3e-05 24.3 4.3 3e-05 24.3 4.3 2.6 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_24 PF13412.6 EGC38698.1 - 0.046 13.3 0.0 0.37 10.4 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding FAM176 PF14851.6 EGC38698.1 - 4.5 6.9 21.6 1.4 8.6 3.9 3.1 3 0 0 3 3 3 0 FAM176 family PAC4 PF16093.5 EGC38699.1 - 3.4e-11 43.2 0.0 4.2e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome assembly chaperone 4 DUF5503 PF17607.2 EGC38699.1 - 0.018 15.3 0.2 0.032 14.6 0.2 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF5503) Vault_2 PF17794.1 EGC38701.1 - 0.075 13.4 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Major Vault Protein repeat domain FNIP PF05725.12 EGC38702.1 - 2.4e-76 251.7 62.5 1.5e-16 60.3 2.4 10.6 6 2 4 11 11 11 11 FNIP Repeat PrgU PF09627.10 EGC38702.1 - 0.028 14.4 1.2 4.4 7.3 0.1 2.5 2 0 0 2 2 2 0 PrgU-like protein LRR_5 PF13306.6 EGC38702.1 - 0.051 13.5 0.2 0.051 13.5 0.2 3.7 1 1 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) DEAD PF00270.29 EGC38703.1 - 1.9e-42 145.0 0.0 5.2e-42 143.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC38703.1 - 2.5e-33 114.8 0.0 1.3e-32 112.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC38703.1 - 0.00022 21.3 0.0 0.0005 20.1 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit SecA_DEAD PF07517.14 EGC38703.1 - 0.0046 16.3 0.0 0.0078 15.5 0.0 1.4 1 0 0 1 1 1 1 SecA DEAD-like domain ERCC3_RAD25_C PF16203.5 EGC38703.1 - 0.077 12.2 0.0 0.13 11.4 0.0 1.3 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase zf-CCHC PF00098.23 EGC38703.1 - 0.37 11.0 2.2 0.58 10.3 2.2 1.3 1 0 0 1 1 1 0 Zinc knuckle SPX PF03105.19 EGC38704.1 - 0.0012 18.9 15.3 0.0016 18.4 15.3 1.2 1 0 0 1 1 1 1 SPX domain Hid1 PF12722.7 EGC38704.1 - 0.068 11.3 12.1 0.083 11.0 12.1 1.2 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF996 PF06195.13 EGC38704.1 - 0.12 12.7 3.8 8.3 6.7 2.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF996) LAP1C PF05609.12 EGC38704.1 - 0.41 9.7 17.3 0.049 12.7 13.3 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 1C (LAP1C) Dapper PF15268.6 EGC38704.1 - 0.48 9.2 22.8 0.61 8.9 22.8 1.0 1 0 0 1 1 1 0 Dapper SRP-alpha_N PF04086.13 EGC38704.1 - 1.7 8.5 18.7 3.3 7.6 18.7 1.4 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ndc1_Nup PF09531.10 EGC38704.1 - 2.9 6.5 27.2 5.2 5.6 27.2 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup GREB1 PF15782.5 EGC38704.1 - 3 4.9 18.3 3.8 4.5 18.3 1.0 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer SOG2 PF10428.9 EGC38704.1 - 3 7.0 22.7 4.1 6.5 22.7 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein CCSAP PF15748.5 EGC38704.1 - 3.6 7.7 31.9 5.1 7.2 31.9 1.1 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated EF-hand_4 PF12763.7 EGC38705.1 - 1.7e-29 101.8 25.7 1.4e-12 47.5 0.0 6.6 4 2 1 6 6 6 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.6 EGC38705.1 - 5.3e-09 36.4 1.9 0.0045 17.4 0.1 4.5 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_1 PF00036.32 EGC38705.1 - 1.5e-08 33.6 8.3 0.5 10.0 0.2 5.7 5 0 0 5 5 5 4 EF hand EF-hand_6 PF13405.6 EGC38705.1 - 8.1e-08 31.6 9.3 0.22 11.6 0.2 5.7 5 0 0 5 5 5 3 EF-hand domain DUF812 PF05667.11 EGC38705.1 - 0.00012 21.1 37.1 0.00012 21.1 37.1 2.3 2 1 0 2 2 2 1 Protein of unknown function (DUF812) EF-hand_8 PF13833.6 EGC38705.1 - 0.0095 15.8 4.6 14 5.7 0.0 4.6 4 0 0 4 4 4 1 EF-hand domain pair EF-hand_5 PF13202.6 EGC38705.1 - 0.85 9.2 2.9 5.8 6.6 1.4 2.7 2 0 0 2 2 2 0 EF hand DUF3584 PF12128.8 EGC38705.1 - 2.7 5.4 47.7 3.8 4.9 47.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Nop14 PF04147.12 EGC38706.1 - 1.7e-231 771.1 76.0 1.9e-231 770.9 76.0 1.0 1 0 0 1 1 1 1 Nop14-like family PPR_2 PF13041.6 EGC38707.1 - 0.027 14.7 4.5 9.8 6.5 0.2 4.5 4 0 0 4 4 4 0 PPR repeat family RTTN_N PF14726.6 EGC38707.1 - 0.13 13.0 2.5 8.5 7.3 0.0 4.2 3 1 1 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning PPR PF01535.20 EGC38707.1 - 4.8 7.7 5.4 19 5.8 0.0 4.4 5 0 0 5 5 5 0 PPR repeat Ank_4 PF13637.6 EGC38708.1 - 2.9e-10 40.4 0.8 0.06 13.9 0.0 7.0 6 1 1 7 7 7 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC38708.1 - 2.3e-06 28.1 3.7 0.62 10.7 0.0 5.1 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) SR-25 PF10500.9 EGC38708.1 - 3.8e-05 23.4 13.9 3.8e-05 23.4 13.9 2.1 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ank_3 PF13606.6 EGC38708.1 - 0.032 14.8 1.7 51 4.9 0.0 6.0 7 0 0 7 7 5 0 Ankyrin repeat FBD PF08387.10 EGC38708.1 - 0.033 14.1 0.0 14 5.7 0.0 3.5 3 0 0 3 3 3 0 FBD SWIM PF04434.17 EGC38708.1 - 0.033 13.9 0.1 0.065 12.9 0.1 1.5 1 0 0 1 1 1 0 SWIM zinc finger Menin PF05053.13 EGC38708.1 - 0.066 11.6 16.9 0.13 10.5 16.9 1.4 1 0 0 1 1 1 0 Menin Phosphonate-bd PF12974.7 EGC38708.1 - 0.15 11.7 0.0 0.82 9.2 0.0 2.0 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein DUF3446 PF11928.8 EGC38708.1 - 0.17 12.2 11.8 0.53 10.6 11.4 2.0 2 0 0 2 2 2 0 Early growth response N-terminal domain DUF3123 PF11321.8 EGC38708.1 - 1.3 9.7 3.9 27 5.5 4.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3123) PAP1 PF08601.10 EGC38708.1 - 1.9 8.1 32.2 0.031 14.0 23.5 2.2 2 0 0 2 2 2 0 Transcription factor PAP1 CCDC24 PF15669.5 EGC38708.1 - 5.7 6.8 9.5 4.4 7.1 7.0 2.0 2 0 0 2 2 2 0 Coiled-coil domain-containing protein 24 family Mito_carr PF00153.27 EGC38709.1 - 4.2e-51 170.8 6.7 9.4e-19 67.1 0.3 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein BUD22 PF09073.10 EGC38710.1 - 4.6 6.5 22.6 5.2 6.3 22.6 1.1 1 0 0 1 1 1 0 BUD22 Ras PF00071.22 EGC38711.1 - 2.5e-19 69.4 1.8 5.2e-19 68.4 1.8 1.5 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC38711.1 - 3.9e-06 27.1 1.3 1.1e-05 25.7 0.5 2.2 2 1 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Pkinase_Tyr PF07714.17 EGC38713.1 - 8.6e-48 162.9 0.0 1.4e-47 162.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase COR PF16095.5 EGC38713.1 - 4.5e-41 140.8 0.3 2e-27 96.3 0.0 2.5 2 0 0 2 2 2 2 C-terminal of Roc, COR, domain Pkinase PF00069.25 EGC38713.1 - 1.9e-40 138.9 0.0 1.2e-39 136.3 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Roc PF08477.13 EGC38713.1 - 5.2e-23 81.5 0.3 9.2e-17 61.4 0.0 3.2 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase LRR_8 PF13855.6 EGC38713.1 - 1.9e-21 75.6 58.9 1.1e-09 37.9 7.8 7.7 7 1 0 7 7 7 3 Leucine rich repeat LRR_4 PF12799.7 EGC38713.1 - 9.3e-17 60.9 63.5 3e-07 30.6 5.7 9.2 5 3 4 9 9 9 5 Leucine Rich repeats (2 copies) RhoGEF PF00621.20 EGC38713.1 - 1e-13 51.9 8.2 8.7e-10 39.1 3.0 3.8 4 0 0 4 4 4 2 RhoGEF domain Ras PF00071.22 EGC38713.1 - 5.6e-12 45.5 0.0 4.6e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 Ras family LRR_6 PF13516.6 EGC38713.1 - 0.00075 19.4 52.4 0.11 12.5 0.0 11.3 12 0 0 12 12 12 3 Leucine Rich repeat Gtr1_RagA PF04670.12 EGC38713.1 - 0.0053 16.2 0.0 0.017 14.5 0.0 1.9 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region LRR_1 PF00560.33 EGC38713.1 - 0.01 16.3 36.7 4.6 8.2 0.2 10.9 8 1 1 9 9 9 3 Leucine Rich Repeat MMR_HSR1 PF01926.23 EGC38713.1 - 0.016 15.3 0.0 0.052 13.6 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase PH_16 PF17838.1 EGC38713.1 - 0.099 12.5 0.9 0.7 9.7 0.9 2.3 1 1 0 1 1 1 0 PH domain CBM49 PF09478.10 EGC38714.1 - 1.5e-12 47.7 2.0 2.2e-12 47.1 2.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PsbH PF00737.20 EGC38714.1 - 0.68 9.7 6.0 1.2 9.0 6.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein E1-E2_ATPase PF00122.20 EGC38715.1 - 3.9e-20 72.1 0.0 9.7e-20 70.8 0.0 1.6 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGC38715.1 - 1.7e-16 61.2 0.0 8.4e-08 32.7 0.0 3.1 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGC38715.1 - 2.6e-06 27.4 0.0 7.6e-06 25.9 0.0 1.8 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Cation_ATPase_C PF00689.21 EGC38715.1 - 0.00032 20.5 4.4 0.00032 20.5 4.4 2.8 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase_3 PF08282.12 EGC38715.1 - 0.34 10.6 6.0 0.2 11.4 0.2 3.0 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase LicD PF04991.13 EGC38715.1 - 0.65 10.1 4.0 0.77 9.9 1.8 2.1 2 0 0 2 2 2 0 LicD family Kelch_4 PF13418.6 EGC38716.1 - 8.6e-44 147.3 15.9 8.2e-09 35.3 0.2 7.3 6 1 0 6 6 6 5 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC38716.1 - 3e-40 135.6 8.1 4.5e-08 32.5 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_3 PF13415.6 EGC38716.1 - 9.2e-38 127.9 11.4 2.6e-06 27.6 0.1 6.7 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC38716.1 - 1.1e-33 114.4 15.6 3.5e-08 33.4 0.6 6.1 5 1 1 6 6 6 5 Kelch motif Kelch_5 PF13854.6 EGC38716.1 - 1.3e-33 114.4 11.6 9e-07 28.7 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.15 EGC38716.1 - 3.3e-33 112.4 8.6 3.1e-09 36.4 0.2 6.1 6 0 0 6 6 6 5 Kelch motif K-box PF01486.17 EGC38716.1 - 0.00013 22.0 3.7 0.00013 22.0 3.7 2.0 2 0 0 2 2 2 1 K-box region Glyco_hydro_18 PF00704.28 EGC38717.1 - 4.9e-18 65.9 2.1 6.1e-18 65.6 2.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Chordopox_A13L PF05961.11 EGC38717.1 - 0.028 14.7 1.2 0.095 12.9 0.2 2.4 1 1 1 2 2 2 0 Chordopoxvirus A13L protein Mito_carr PF00153.27 EGC38719.1 - 6e-70 231.2 7.3 2.9e-24 84.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EGF_MSP1_1 PF12946.7 EGC38719.1 - 0.033 14.3 0.1 0.48 10.5 0.1 2.3 2 0 0 2 2 2 0 MSP1 EGF domain 1 Nfu_N PF08712.11 EGC38719.1 - 0.054 13.5 0.1 1.1 9.3 0.0 2.7 3 0 0 3 3 3 0 Scaffold protein Nfu/NifU N terminal PT-VENN PF04829.13 EGC38719.1 - 0.064 13.3 2.2 5.7 7.1 0.0 3.3 3 0 0 3 3 3 0 Pre-toxin domain with VENN motif ATP-synt_S1 PF05827.12 EGC38719.1 - 0.077 12.8 0.1 1.2 9.0 0.0 2.6 3 0 0 3 3 3 0 Vacuolar ATP synthase subunit S1 (ATP6S1) Mob1_phocein PF03637.17 EGC38720.1 - 2.4e-72 242.4 0.0 2.9e-72 242.2 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF2053 PF09767.9 EGC38721.1 - 2.2e-39 135.2 10.5 3.2e-39 134.7 10.5 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) ArsP_2 PF11449.8 EGC38721.1 - 0.00028 20.2 0.2 0.00055 19.3 0.1 1.4 1 1 0 1 1 1 1 Putative, 10TM heavy-metal exporter FNIP PF05725.12 EGC38722.1 - 3e-11 43.3 40.8 0.0011 19.0 0.1 9.4 7 2 2 9 9 9 5 FNIP Repeat Methyltransf_7 PF03492.15 EGC38723.1 - 4.2e-35 121.5 5.4 5.9e-35 121.0 5.4 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Metallophos PF00149.28 EGC38724.1 - 9.8e-19 68.7 3.9 1.5e-18 68.1 3.9 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.6 EGC38724.1 - 1.4e-13 51.5 0.7 3.1e-13 50.4 0.7 1.6 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Pur_ac_phosph_N PF16656.5 EGC38724.1 - 3.4e-13 50.0 0.3 9.8e-13 48.5 0.3 1.8 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_2 PF12850.7 EGC38724.1 - 0.0032 17.7 0.2 0.01 16.0 0.2 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 EGC38724.1 - 0.054 12.5 0.0 0.28 10.1 0.0 1.8 2 0 0 2 2 2 0 PhoD-like phosphatase Anoct_dimer PF16178.5 EGC38725.1 - 0.078 12.7 0.5 0.12 12.1 0.5 1.2 1 0 0 1 1 1 0 Dimerisation domain of Ca+-activated chloride-channel, anoctamin Metallophos PF00149.28 EGC38726.1 - 1.8e-21 77.6 3.7 1.8e-21 77.6 3.7 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGC38726.1 - 3.2e-16 59.7 2.2 1.1e-15 57.9 2.2 2.0 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGC38726.1 - 3.5e-14 53.4 0.8 3.5e-14 53.4 0.8 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGC38726.1 - 7.2e-05 23.0 0.0 0.0002 21.6 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 EGC38726.1 - 0.00038 19.6 0.2 0.0023 17.0 0.0 1.9 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos PF00149.28 EGC38727.1 - 4.6e-17 63.2 4.4 4.6e-17 63.2 4.4 2.0 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Pur_ac_phosph_N PF16656.5 EGC38727.1 - 3.7e-16 59.5 1.0 3.7e-16 59.5 1.0 2.0 2 0 0 2 2 2 1 Purple acid Phosphatase, N-terminal domain Metallophos_C PF14008.6 EGC38727.1 - 3.1e-15 56.8 1.5 3.1e-15 56.8 1.5 2.1 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.7 EGC38727.1 - 1.4e-05 25.4 0.0 3.3e-05 24.1 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.10 EGC38727.1 - 6.7e-05 22.1 0.2 0.014 14.5 0.1 2.2 1 1 1 2 2 2 2 PhoD-like phosphatase WD40 PF00400.32 EGC38728.1 - 7.4e-05 23.4 5.0 2.2 9.3 0.0 5.7 6 0 0 6 6 6 2 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38728.1 - 0.003 17.8 0.1 0.67 10.3 0.0 3.3 3 0 0 3 3 3 1 Anaphase-promoting complex subunit 4 WD40 domain SUIM_assoc PF16619.5 EGC38728.1 - 0.12 12.4 4.3 0.11 12.6 2.6 1.8 2 0 0 2 2 2 0 Unstructured region C-term to UIM in Ataxin3 WD40 PF00400.32 EGC38729.1 - 3.6e-31 106.7 6.1 1.7e-05 25.4 0.1 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat WD40_like PF17005.5 EGC38729.1 - 3.1e-07 30.0 1.1 0.1 11.9 0.0 3.4 2 1 1 3 3 3 3 WD40-like domain ANAPC4_WD40 PF12894.7 EGC38729.1 - 0.00036 20.8 0.3 0.066 13.5 0.0 3.5 1 1 3 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain BRCA-2_OB1 PF09103.10 EGC38730.1 - 2.3e-39 134.1 1.0 2.3e-39 134.1 1.0 3.2 2 1 0 2 2 2 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA2 PF00634.18 EGC38730.1 - 9.5e-21 73.2 0.0 0.0054 16.4 0.0 6.7 6 0 0 6 6 6 6 BRCA2 repeat BRCA-2_helical PF09169.10 EGC38730.1 - 9.9e-18 64.5 1.3 2.2e-16 60.1 1.3 2.5 1 1 0 1 1 1 1 BRCA2, helical CaM-KIIN PF15170.6 EGC38730.1 - 0.00065 19.8 14.9 12 6.2 0.0 7.1 6 1 2 8 8 8 3 Calcium/calmodulin-dependent protein kinase II inhibitor Sld5 PF05916.11 EGC38731.1 - 0.032 14.7 0.1 0.038 14.4 0.1 1.1 1 0 0 1 1 1 0 GINS complex protein DUF1736 PF08409.11 EGC38732.1 - 4.5e-20 71.4 1.9 2e-19 69.3 1.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_1 PF00515.28 EGC38732.1 - 1e-12 47.3 7.8 1.1e-05 25.0 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC38732.1 - 1.9e-12 46.2 4.8 1.7e-05 24.6 0.0 5.5 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC38732.1 - 2.1e-12 47.1 2.2 2.4e-05 24.5 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC38732.1 - 5.3e-09 36.1 2.3 0.22 12.2 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38732.1 - 2.2e-08 33.7 6.6 0.0049 17.0 0.3 5.4 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.6 EGC38732.1 - 1.1e-07 31.4 1.8 0.32 10.7 0.1 4.7 3 1 1 4 4 4 2 TPR repeat TPR_17 PF13431.6 EGC38732.1 - 1.9e-06 27.8 1.7 0.1 13.0 0.0 4.5 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC38732.1 - 0.00019 21.2 0.6 2.5 8.3 0.0 4.5 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC38732.1 - 0.002 18.8 0.0 34 5.6 0.0 4.3 4 1 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC38732.1 - 0.0091 15.8 0.1 3.2 7.8 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC38732.1 - 0.017 15.6 0.4 24 5.5 0.0 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.6 EGC38732.1 - 0.11 13.1 0.0 41 4.9 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF1772 PF08592.11 EGC38732.1 - 0.19 12.1 0.6 2.7 8.3 0.2 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF1772) Mucin PF01456.17 EGC38732.1 - 0.25 11.3 11.2 0.61 10.1 11.2 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein PBP1_TM PF14812.6 EGC38732.1 - 0.25 11.7 1.8 4.4 7.7 0.5 3.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ANAPC3 PF12895.7 EGC38732.1 - 1.5 9.1 8.4 3.9 7.8 0.3 4.5 4 1 1 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DUF4834 PF16118.5 EGC38732.1 - 2.8 9.0 7.8 15 6.6 0.0 4.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4834) Copine PF07002.16 EGC38734.1 - 3.5e-73 245.7 0.0 5.6e-73 245.0 0.0 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.30 EGC38734.1 - 3.1e-22 78.8 1.3 1.9e-12 47.3 0.1 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.9 EGC38734.1 - 0.00035 20.8 0.0 0.00068 19.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.28 EGC38734.1 - 0.005 17.1 0.1 0.01 16.1 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF3484 PF11983.8 EGC38734.1 - 5.7 8.1 6.5 16 6.7 6.5 1.7 1 0 0 1 1 1 0 Membrane-attachment and polymerisation-promoting switch Fungus-induced PF10917.8 EGC38735.1 - 0.021 15.1 0.3 0.036 14.4 0.3 1.5 1 1 0 1 1 1 0 Fungus-induced protein OAD_gamma PF04277.13 EGC38735.1 - 0.099 13.2 0.3 0.11 13.1 0.3 1.3 1 1 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Bap31 PF05529.12 EGC38735.1 - 0.11 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Bap31/Bap29 transmembrane region DUF4269 PF14091.6 EGC38736.1 - 1.8e-58 197.1 0.7 2.1e-58 196.9 0.7 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) DUF5300 PF17224.3 EGC38737.1 - 0.013 15.7 0.1 0.017 15.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5300) Phage_TAC_4 PF08748.11 EGC38737.1 - 0.094 13.0 0.0 0.11 12.9 0.0 1.2 1 0 0 1 1 1 0 Phage tail assembly chaperone DS PF01916.17 EGC38738.1 - 6.3e-133 442.5 0.0 7.2e-133 442.2 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RCC1_2 PF13540.6 EGC38739.1 - 2.6e-27 94.0 8.4 1.1e-10 41.0 0.9 5.2 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.18 EGC38739.1 - 8.6e-19 67.9 2.9 0.00011 22.7 0.0 7.0 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.31 EGC38739.1 - 1.8e-07 31.4 7.6 8.1e-07 29.3 0.1 3.9 4 0 0 4 4 4 1 BTB/POZ domain Macro PF01661.21 EGC38739.1 - 0.28 11.2 0.9 2.3 8.3 0.1 2.5 2 0 0 2 2 2 0 Macro domain zf-TRAF PF02176.18 EGC38740.1 - 5.4e-20 71.8 18.2 4.4e-14 52.9 7.6 4.3 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.6 EGC38740.1 - 6.1e-07 29.2 12.1 6.1e-07 29.2 12.1 3.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.16 EGC38740.1 - 2.1e-06 27.8 15.9 0.0001 22.3 1.1 3.6 2 1 2 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC38740.1 - 9.1e-05 22.2 14.4 9.1e-05 22.2 14.4 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF_2 PF15965.5 EGC38740.1 - 0.0016 18.9 36.4 0.018 15.5 8.2 4.0 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC38740.1 - 0.0027 18.0 13.5 0.0027 18.0 13.5 3.8 3 2 1 4 4 4 1 Ring finger domain zf_UBZ PF18439.1 EGC38740.1 - 0.042 13.5 1.7 0.042 13.5 1.7 4.4 6 1 1 7 7 7 0 Ubiquitin-Binding Zinc Finger YkuI_C PF10388.9 EGC38740.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.0 1 1 2 3 3 3 0 EAL-domain associated signalling protein domain zf_C2HC_14 PF18574.1 EGC38740.1 - 6.2 6.7 0.0 2.1 8.2 0.8 6.0 6 0 0 6 6 6 0 C2HC Zing finger domain zf-C3HC4_2 PF13923.6 EGC38741.1 - 0.14 12.0 0.8 0.28 11.1 0.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TRM13 PF05206.14 EGC38742.1 - 2.1e-72 243.8 7.6 2.1e-72 243.8 7.6 2.3 2 0 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.8 EGC38742.1 - 1.1e-10 41.1 4.6 1.1e-10 41.1 4.6 2.1 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.12 EGC38742.1 - 5.7e-09 35.7 1.0 2.1e-08 33.9 1.0 2.1 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger UNC80 PF15778.5 EGC38742.1 - 0.022 14.4 0.3 0.064 12.9 0.0 1.9 2 0 0 2 2 2 0 Cation channel complex component UNC80 KIX_2 PF16987.5 EGC38743.1 - 2.9e-06 27.2 0.1 4.4e-06 26.6 0.1 1.3 1 0 0 1 1 1 1 KIX domain Glyoxalase_3 PF13468.6 EGC38743.1 - 0.046 13.8 0.0 0.077 13.1 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain KIX PF02172.16 EGC38743.1 - 0.046 14.0 0.1 0.075 13.3 0.1 1.3 1 0 0 1 1 1 0 KIX domain TFIIS_M PF07500.14 EGC38743.1 - 0.11 12.9 0.3 0.16 12.4 0.3 1.2 1 0 0 1 1 1 0 Transcription factor S-II (TFIIS), central domain TRIQK PF15168.6 EGC38745.1 - 0.07 13.0 0.5 0.19 11.7 0.1 1.8 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family Tmemb_9 PF05434.11 EGC38745.1 - 0.08 12.8 1.2 0.17 11.8 1.2 1.6 1 0 0 1 1 1 0 TMEM9 NAD_binding_10 PF13460.6 EGC38746.1 - 1e-08 35.3 0.0 1.4e-08 34.9 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC38746.1 - 0.0022 17.2 0.0 0.005 16.0 0.0 1.6 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.24 EGC38746.1 - 0.0025 18.2 0.1 0.0086 16.5 0.0 1.9 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.21 EGC38746.1 - 0.0062 16.0 0.0 0.0091 15.5 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RRM_1 PF00076.22 EGC38747.1 - 1.3e-81 268.4 4.8 9.5e-22 76.6 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.18 EGC38747.1 - 1.9e-20 72.8 0.2 9.5e-20 70.6 0.1 2.1 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain RRM_5 PF13893.6 EGC38747.1 - 1.2e-12 47.5 0.1 0.018 14.6 0.0 4.2 1 1 3 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM PF05172.13 EGC38747.1 - 6.4e-10 38.9 0.0 0.0041 17.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGC38747.1 - 1.1e-06 28.6 0.4 0.58 10.2 0.1 4.2 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.6 EGC38747.1 - 1.2e-06 28.4 0.1 2 8.5 0.0 3.7 4 0 0 4 4 4 3 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGC38747.1 - 6.6e-06 25.9 0.1 1.4 8.8 0.0 3.9 4 0 0 4 4 4 3 Occluded RNA-recognition motif OB_RNB PF08206.11 EGC38747.1 - 0.00022 20.8 2.1 0.032 13.9 0.1 3.3 3 0 0 3 3 3 1 Ribonuclease B OB domain RRM_7 PF16367.5 EGC38747.1 - 0.00045 20.3 0.1 6.7 6.9 0.1 4.8 4 2 0 4 4 4 1 RNA recognition motif DbpA PF03880.15 EGC38747.1 - 0.031 14.3 0.0 6.1 6.9 0.0 2.8 2 0 0 2 2 2 0 DbpA RNA binding domain DNA_ligase_IV PF11411.8 EGC38747.1 - 0.081 13.1 1.7 6.6 6.9 0.1 3.3 3 0 0 3 3 3 0 DNA ligase IV PhetRS_B1 PF18262.1 EGC38747.1 - 0.17 12.2 0.3 7.1 6.9 0.0 2.9 3 0 0 3 3 3 0 Phe-tRNA synthetase beta subunit B1 domain SF1-HH PF16275.5 EGC38748.1 - 8.7e-38 129.1 0.9 3.8e-37 127.1 0.9 2.2 1 0 0 1 1 1 1 Splicing factor 1 helix-hairpin domain KH_1 PF00013.29 EGC38748.1 - 3.2e-08 33.3 0.3 6.7e-08 32.3 0.3 1.6 1 0 0 1 1 1 1 KH domain zf-CCHC PF00098.23 EGC38748.1 - 0.094 12.8 0.8 0.18 12.0 0.8 1.5 1 0 0 1 1 1 0 Zinc knuckle FNIP PF05725.12 EGC38749.1 - 2.7e-07 30.6 30.9 0.0047 17.1 0.2 9.0 7 4 2 9 9 9 7 FNIP Repeat PP_kinase PF02503.17 EGC38750.1 - 2.6e-64 216.6 2.0 4.6e-64 215.7 2.0 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_C PF13090.6 EGC38750.1 - 2.2e-63 212.8 1.7 2.3e-63 212.8 0.2 1.8 2 0 0 2 2 2 1 Polyphosphate kinase C-terminal domain 2 PP_kinase_C_1 PF17941.1 EGC38750.1 - 1.7e-60 203.4 0.2 8.1e-59 197.9 0.0 2.2 1 1 1 2 2 2 1 Polyphosphate kinase C-terminal domain 1 PP_kinase_N PF13089.6 EGC38750.1 - 9.6e-20 70.9 1.6 1.5e-19 70.2 0.6 2.0 2 0 0 2 2 2 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.6 EGC38750.1 - 8.3e-10 38.7 0.1 0.0012 18.7 0.1 2.6 2 0 0 2 2 2 2 PLD-like domain RE_NgoFVII PF09565.10 EGC38750.1 - 6.8e-05 22.3 0.0 6.8e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 NgoFVII restriction endonuclease CTK3 PF12243.8 EGC38750.1 - 0.14 12.1 1.3 2.3 8.2 0.1 3.1 3 0 0 3 3 3 0 CTD kinase subunit gamma CTK3 p450 PF00067.22 EGC38751.1 - 1.7e-87 294.1 0.1 1.9e-87 293.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.23 EGC38752.1 - 5.2e-61 206.7 25.9 5.2e-61 206.7 25.9 2.4 2 0 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGC38752.1 - 1.4e-33 116.3 0.4 3.8e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGC38752.1 - 0.00015 21.3 5.1 0.0007 19.1 1.9 2.6 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.9 EGC38752.1 - 0.00095 18.1 0.1 0.67 8.7 0.1 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_22 PF13401.6 EGC38752.1 - 0.002 18.4 0.2 0.011 16.0 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.6 EGC38752.1 - 0.0039 16.9 0.0 0.012 15.3 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain RsgA_GTPase PF03193.16 EGC38752.1 - 0.015 15.2 0.1 0.043 13.7 0.0 1.8 2 0 0 2 2 2 0 RsgA GTPase AAA_16 PF13191.6 EGC38752.1 - 0.084 13.3 0.1 0.28 11.5 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.6 EGC38752.1 - 0.11 12.2 0.0 0.33 10.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain EphA2_TM PF14575.6 EGC38752.1 - 8.7 7.3 7.9 6.1 7.8 0.1 4.0 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_18 PF00704.28 EGC38753.1 - 2e-05 24.5 0.0 2.4e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.13 EGC38753.1 - 0.0094 15.4 0.0 0.014 14.8 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 85 NLPC_P60 PF00877.19 EGC38754.1 - 4.2e-11 42.8 0.1 5.4e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family RFX5_N PF18326.1 EGC38754.1 - 0.0057 16.4 0.1 0.0098 15.6 0.1 1.3 1 0 0 1 1 1 1 RFX5 N-terminal domain Pkinase PF00069.25 EGC38755.1 - 2.5e-39 135.3 20.1 1e-20 74.2 4.6 3.4 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38755.1 - 2.1e-21 76.4 2.1 4.3e-10 39.3 0.8 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC38755.1 - 3.2e-07 29.5 2.2 2.5e-05 23.3 0.1 2.3 2 0 0 2 2 2 2 Fungal protein kinase Kinase-like PF14531.6 EGC38755.1 - 0.011 15.1 0.1 0.15 11.3 0.0 2.4 2 0 0 2 2 2 0 Kinase-like Kdo PF06293.14 EGC38755.1 - 0.023 14.1 0.0 0.066 12.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC38755.1 - 0.12 12.3 0.1 0.5 10.2 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CHCH PF06747.13 EGC38756.1 - 0.0013 18.8 4.2 0.0023 18.0 4.2 1.4 1 0 0 1 1 1 1 CHCH domain DEC-1_N PF04625.13 EGC38756.1 - 0.018 14.1 5.5 0.02 13.9 5.5 1.2 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Pet191_N PF10203.9 EGC38756.1 - 0.026 14.8 0.9 0.048 14.0 0.9 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF2076 PF09849.9 EGC38756.1 - 0.045 13.8 16.6 0.17 11.9 16.5 1.7 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF5401 PF17380.2 EGC38756.1 - 3.3 5.7 5.4 5.2 5.0 5.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5401) Archease PF01951.16 EGC38757.1 - 1.6e-42 145.0 2.5 1.8e-42 144.9 2.5 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) DUF2703 PF10865.8 EGC38757.1 - 0.0094 16.1 0.1 0.019 15.1 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2703) Ras PF00071.22 EGC38758.1 - 2.1e-36 124.9 0.0 2.5e-36 124.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38758.1 - 1.7e-18 67.0 0.0 2.9e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38758.1 - 2.2e-09 37.0 0.0 2.8e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC38758.1 - 0.0061 16.1 0.1 0.6 9.6 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGC38758.1 - 0.0083 15.6 0.1 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC38758.1 - 0.047 13.8 0.1 0.38 10.9 0.0 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase NLPC_P60 PF00877.19 EGC38759.1 - 1.4e-10 41.1 0.0 2.1e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family FNIP PF05725.12 EGC38760.1 - 7.1e-38 128.5 27.5 1.1e-16 60.7 1.1 7.6 5 2 3 8 8 8 8 FNIP Repeat EGF_2 PF07974.13 EGC38761.1 - 8.9e-20 70.8 120.6 4.3e-05 23.8 8.7 8.0 6 1 1 7 7 7 6 EGF-like domain TIG PF01833.24 EGC38761.1 - 1.2e-05 25.3 12.7 9.4e-05 22.4 1.6 4.8 5 0 0 5 5 5 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC38761.1 - 0.0065 16.6 101.0 0.099 12.8 7.4 7.2 2 2 4 7 7 7 5 Laminin EGF domain DUF5124 PF17160.4 EGC38761.1 - 0.01 16.6 0.5 2.6 8.8 0.0 3.8 4 0 0 4 4 4 0 Domain of unknown function (DUF5124) SKG6 PF08693.10 EGC38761.1 - 0.15 11.5 3.8 0.17 11.3 2.5 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain WD40 PF00400.32 EGC38762.1 - 2.4e-41 138.9 26.7 3.6e-07 30.8 0.7 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38762.1 - 1.3e-18 67.0 7.6 0.0019 18.5 0.3 6.3 1 1 4 6 6 6 6 Anaphase-promoting complex subunit 4 WD40 domain Frtz PF11768.8 EGC38762.1 - 0.0092 14.3 0.0 0.16 10.3 0.0 2.0 1 1 1 2 2 2 2 WD repeat-containing and planar cell polarity effector protein Fritz WD40_like PF17005.5 EGC38762.1 - 0.088 12.1 0.0 0.42 9.9 0.0 1.9 2 0 0 2 2 2 0 WD40-like domain ketoacyl-synt PF00109.26 EGC38764.1 - 3e-64 217.0 0.0 4.7e-64 216.4 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.22 EGC38764.1 - 8.8e-33 112.8 0.0 4.7e-32 110.5 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38764.1 - 2.4e-24 86.2 0.1 6e-24 84.9 0.1 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC38764.1 - 6.6e-21 74.9 7.4 2.3e-20 73.2 0.0 4.9 4 0 0 4 4 4 1 Methyltransferase domain Acyl_transf_1 PF00698.21 EGC38764.1 - 3.7e-19 69.4 0.0 2.1e-14 53.8 0.0 2.5 1 1 1 2 2 2 2 Acyl transferase domain KAsynt_C_assoc PF16197.5 EGC38764.1 - 3.8e-18 66.0 0.5 1.4e-17 64.1 0.2 2.2 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC38764.1 - 4.4e-18 65.5 0.0 6.7e-18 64.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC38764.1 - 7.2e-10 40.0 0.0 3.5e-09 37.8 0.0 2.2 3 0 0 3 3 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38764.1 - 3.3e-06 27.0 0.1 7.5e-06 25.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC38764.1 - 1.9e-05 24.2 0.0 4.5e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGC38764.1 - 0.00012 22.3 0.2 0.00029 21.1 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EGC38764.1 - 0.00023 21.0 0.0 0.00051 19.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC38764.1 - 0.00055 20.5 0.0 0.0027 18.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF1430 PF07242.11 EGC38764.1 - 0.041 14.1 3.4 0.065 13.5 1.0 2.8 2 0 0 2 2 1 0 Protein of unknown function (DUF1430) Methyltransf_31 PF13847.6 EGC38764.1 - 0.072 12.9 5.4 0.94 9.3 0.0 4.0 4 0 0 4 4 4 0 Methyltransferase domain FNIP PF05725.12 EGC38765.1 - 2.4e-78 258.1 88.1 1.4e-08 34.8 1.3 15.1 7 3 11 18 18 18 17 FNIP Repeat ketoacyl-synt PF00109.26 EGC38766.1 - 5.2e-62 209.7 0.0 1.2e-61 208.6 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC38766.1 - 6.3e-43 147.5 0.0 1.4e-42 146.3 0.0 1.6 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC38766.1 - 2.3e-32 111.5 0.0 1.2e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC38766.1 - 1.4e-24 87.0 0.1 3.5e-24 85.7 0.1 1.7 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC38766.1 - 9.6e-22 77.6 1.5 2.7e-20 72.9 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC38766.1 - 7.1e-20 71.4 0.0 1.1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC38766.1 - 4.1e-16 59.4 0.9 1.1e-15 58.1 0.3 2.2 2 0 0 2 2 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC38766.1 - 2.4e-10 41.6 0.0 6.5e-10 40.2 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC38766.1 - 2.9e-05 23.9 0.1 7.4e-05 22.6 0.1 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.6 EGC38766.1 - 4.2e-05 23.4 0.0 0.00014 21.7 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC38766.1 - 0.00011 21.7 0.1 0.0003 20.3 0.1 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.25 EGC38766.1 - 0.0005 20.4 0.1 0.0012 19.2 0.1 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.12 EGC38766.1 - 0.00054 20.5 0.0 0.0018 18.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC38766.1 - 0.017 14.9 0.2 0.68 9.7 0.0 3.1 2 0 0 2 2 2 0 Methyltransferase domain DS PF01916.17 EGC38767.1 - 2.9e-128 427.1 0.0 3.3e-128 426.9 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DEAD PF00270.29 EGC38768.1 - 1.2e-37 129.4 0.1 3.2e-37 128.0 0.0 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC38768.1 - 3.6e-25 88.5 1.0 1.2e-24 86.8 0.1 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC38768.1 - 3.1e-09 37.0 0.0 3.1e-09 37.0 0.0 3.4 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit SWI2_SNF2 PF18766.1 EGC38768.1 - 0.0016 18.1 0.0 0.0016 18.1 0.0 1.8 2 0 0 2 2 2 1 SWI2/SNF2 ATPase AAA_22 PF13401.6 EGC38768.1 - 0.0097 16.2 1.5 0.17 12.1 1.5 2.4 1 1 0 1 1 1 1 AAA domain NTP_transf_2 PF01909.23 EGC38768.1 - 0.025 14.8 0.2 0.71 10.2 0.0 2.9 2 1 1 3 3 3 0 Nucleotidyltransferase domain AroM PF07302.11 EGC38768.1 - 0.092 12.1 0.1 0.15 11.4 0.1 1.3 1 0 0 1 1 1 0 AroM protein DUF4611 PF15387.6 EGC38768.1 - 1 9.7 8.8 3.7 7.8 8.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.9 EGC38768.1 - 2 7.4 13.3 3 6.9 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Xpo1 PF08389.12 EGC38770.1 - 1.4e-12 47.9 1.7 1.4e-12 47.9 1.7 5.2 4 2 2 7 7 7 1 Exportin 1-like protein Importin_rep_3 PF18806.1 EGC38770.1 - 1.7e-05 24.8 0.0 0.00014 21.8 0.0 2.4 2 0 0 2 2 2 1 Importin 13 repeat Importin_rep PF18773.1 EGC38770.1 - 0.00037 20.1 0.6 0.0057 16.3 0.0 2.8 3 0 0 3 3 3 1 Importin 13 repeat DUF1722 PF08349.11 EGC38770.1 - 0.066 13.5 0.2 0.42 10.9 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1722) MIG-14_Wnt-bd PF06664.12 EGC38771.1 - 1.1 8.4 44.1 0.014 14.6 25.5 2.6 2 1 1 3 3 3 0 Wnt-binding factor required for Wnt secretion SET PF00856.28 EGC38772.1 - 2.1e-15 57.5 5.1 2.9e-14 53.8 5.1 2.3 1 1 0 1 1 1 1 SET domain SSP160 PF06933.11 EGC38772.1 - 0.029 12.6 4.4 0.04 12.1 4.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 BSP_II PF05432.11 EGC38772.1 - 6.9 6.3 12.3 0.51 10.0 2.8 2.1 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Peptidase_C97 PF05903.14 EGC38773.1 - 6.1e-05 22.9 1.1 0.00012 22.0 1.1 1.5 1 1 0 1 1 1 1 PPPDE putative peptidase domain Kunitz_BPTI PF00014.23 EGC38773.1 - 0.017 15.3 0.0 0.037 14.3 0.0 1.5 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Peptidase_C97 PF05903.14 EGC38774.1 - 0.00033 20.5 0.1 0.00042 20.2 0.1 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain DUF4348 PF14254.6 EGC38775.1 - 0.0086 15.5 0.2 0.014 14.8 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4348) Pollen_allerg_1 PF01357.21 EGC38776.1 - 0.00054 19.9 0.0 0.0012 18.8 0.0 1.6 1 0 0 1 1 1 1 Pollen allergen Pkinase PF00069.25 EGC38777.1 - 6e-58 196.3 0.0 1.3e-57 195.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC38777.1 - 7.2e-36 123.8 0.0 1.5e-35 122.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.27 EGC38777.1 - 7.8e-31 107.0 0.1 7.8e-31 107.0 0.1 2.4 3 0 0 3 3 3 1 RhoGAP domain Kinase-like PF14531.6 EGC38777.1 - 0.00048 19.5 0.0 0.0025 17.2 0.0 2.1 1 1 0 1 1 1 1 Kinase-like PIF1 PF05970.14 EGC38777.1 - 0.0015 17.8 0.8 0.0015 17.8 0.8 2.2 2 0 0 2 2 2 1 PIF1-like helicase PH PF00169.29 EGC38777.1 - 0.014 15.9 6.1 0.22 12.0 0.2 2.8 2 0 0 2 2 2 0 PH domain Connexin PF00029.19 EGC38777.1 - 0.32 10.7 4.6 0.73 9.5 4.6 1.5 1 0 0 1 1 1 0 Connexin Presenilin PF01080.17 EGC38777.1 - 3.8 6.2 8.4 9.5 4.9 8.4 1.7 1 0 0 1 1 1 0 Presenilin Chromo PF00385.24 EGC38778.1 - 4.6e-14 52.1 3.8 6.1e-14 51.7 3.8 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGC38778.1 - 0.072 13.3 0.2 0.1 12.7 0.2 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 FNIP PF05725.12 EGC38779.1 - 3.2e-21 75.2 11.7 7.1e-11 42.1 0.6 3.1 3 0 0 3 3 3 3 FNIP Repeat DUF3641 PF12345.8 EGC38780.1 - 1 9.4 5.8 0.56 10.2 0.1 3.6 4 1 0 4 4 4 0 Protein of unknown function (DUF3641) DNA_topoisoIV PF00521.20 EGC38781.1 - 1.6e-115 386.5 0.2 1.6e-115 386.5 0.2 2.1 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A TOPRIM_C PF16898.5 EGC38781.1 - 1e-40 138.9 8.1 1e-40 138.9 8.1 3.2 2 0 0 2 2 2 1 C-terminal associated domain of TOPRIM DNA_gyraseB PF00204.25 EGC38781.1 - 5.3e-23 81.4 0.4 1.8e-22 79.7 0.4 1.9 1 0 0 1 1 1 1 DNA gyrase B HATPase_c PF02518.26 EGC38781.1 - 5.6e-10 39.7 0.1 2.1e-09 37.8 0.1 2.1 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Toprim PF01751.22 EGC38781.1 - 3.2e-07 30.5 0.0 1.6e-06 28.2 0.0 2.3 1 0 0 1 1 1 1 Toprim domain TPK_catalytic PF04263.16 EGC38781.1 - 0.078 13.0 4.0 1.1 9.4 0.2 3.2 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, catalytic domain Kelch_4 PF13418.6 EGC38782.1 - 4.2e-36 122.7 11.2 3.8e-09 36.4 0.2 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC38782.1 - 2.5e-34 116.9 9.4 2.5e-10 40.4 0.2 5.7 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC38782.1 - 3.1e-34 116.1 21.5 3.1e-11 43.1 0.4 6.9 5 1 2 7 7 7 5 Kelch motif Kelch_1 PF01344.25 EGC38782.1 - 4.8e-33 112.5 7.6 7.2e-08 31.9 0.3 5.5 5 0 0 5 5 5 4 Kelch motif Kelch_5 PF13854.6 EGC38782.1 - 1.5e-29 101.5 16.2 1.5e-07 31.3 0.1 6.7 6 0 0 6 6 6 6 Kelch motif RasGEF PF00617.19 EGC38782.1 - 4.5e-29 101.9 2.4 8.5e-29 101.0 0.6 2.4 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC38782.1 - 5.6e-25 87.6 0.0 2.4e-24 85.6 0.0 2.1 1 0 0 1 1 1 1 RasGEF N-terminal motif Kelch_2 PF07646.15 EGC38782.1 - 5.2e-24 83.3 11.7 1.1e-07 31.5 0.2 6.6 6 0 0 6 6 6 5 Kelch motif MmgE_PrpD PF03972.14 EGC38783.1 - 2.4e-131 438.3 0.0 2.9e-131 438.1 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DDE_3 PF13358.6 EGC38784.1 - 0.014 15.2 0.1 0.018 14.8 0.1 1.2 1 0 0 1 1 1 0 DDE superfamily endonuclease SnoaL_2 PF12680.7 EGC38785.1 - 2.6e-25 89.0 5.7 0.0024 18.5 0.0 5.8 6 0 0 6 6 6 5 SnoaL-like domain HopJ PF08888.11 EGC38785.1 - 1e-09 38.6 7.0 1.7 8.9 0.0 5.5 5 0 0 5 5 5 5 HopJ type III effector protein SnoaL PF07366.12 EGC38785.1 - 1e-06 28.6 19.2 1.8 8.4 0.2 7.8 5 5 0 5 5 5 5 SnoaL-like polyketide cyclase PAS_8 PF13188.7 EGC38785.1 - 0.00021 21.2 0.1 1.2e+02 2.8 0.0 5.8 5 0 0 5 5 5 0 PAS domain NES_C_h PF18208.1 EGC38785.1 - 0.00038 20.7 6.1 38 4.6 0.0 5.7 5 0 0 5 5 5 0 Nicking enzyme C-terminal middle helical domain MRP-S34 PF16053.5 EGC38785.1 - 0.00047 19.8 2.5 5.4 6.7 0.0 4.6 4 0 0 4 4 4 1 Mitochondrial 28S ribosomal protein S34 DNA_pol3_delta2 PF13177.6 EGC38785.1 - 0.011 15.5 15.0 3.8 7.3 0.1 5.1 5 0 0 5 5 5 0 DNA polymerase III, delta subunit DUF5444 PF17519.2 EGC38785.1 - 0.051 13.6 2.3 2.4e+02 1.8 0.0 5.0 5 0 0 5 5 5 0 Family of unknown function (DUF5444) Ins_allergen_rp PF06757.13 EGC38785.1 - 0.064 13.2 20.0 16 5.4 0.2 5.2 5 0 0 5 5 5 0 Insect allergen related repeat, nitrile-specifier detoxification SAPIS-gp6 PF16722.5 EGC38785.1 - 0.21 12.0 6.0 61 4.1 0.0 5.3 5 0 0 5 5 5 0 Pathogenicity island protein gp6 in Staphylococcus WD40 PF00400.32 EGC38786.1 - 1.5e-23 82.6 12.7 2.2e-05 25.1 0.0 7.7 7 0 0 7 7 7 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38786.1 - 4.7e-13 49.2 2.9 0.045 14.1 0.0 5.3 1 1 4 5 5 5 5 Anaphase-promoting complex subunit 4 WD40 domain zf-C3HC4_2 PF13923.6 EGC38786.1 - 1.9e-08 34.0 7.3 5e-08 32.7 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38786.1 - 5.4e-07 29.8 6.3 1.9e-06 28.1 6.3 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC38786.1 - 6.6e-07 29.1 7.6 2e-06 27.6 7.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC38786.1 - 5.6e-06 26.2 7.1 5.6e-06 26.2 7.1 2.0 3 0 0 3 3 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC38786.1 - 4e-05 23.6 4.4 0.00012 22.0 4.4 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC38786.1 - 5.5e-05 22.9 4.2 5.5e-05 22.9 4.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGC38786.1 - 6.9e-05 23.0 0.0 0.00028 21.0 0.0 2.1 1 0 0 1 1 1 1 U-box domain Prok-RING_4 PF14447.6 EGC38786.1 - 0.00013 21.7 3.9 0.00033 20.5 3.9 1.7 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC38786.1 - 0.00038 20.7 5.7 0.00038 20.7 5.7 2.5 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC38786.1 - 0.00069 19.7 7.0 0.0033 17.6 7.1 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-P11 PF03854.14 EGC38786.1 - 0.037 13.7 4.3 0.04 13.6 1.6 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.6 EGC38786.1 - 0.35 10.7 4.8 0.98 9.3 4.8 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGC38786.1 - 1.4 8.8 5.2 3.5 7.5 5.2 1.8 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit WD40 PF00400.32 EGC38787.1 - 4.8e-34 115.8 31.6 6e-05 23.7 0.1 11.9 12 1 0 12 12 12 9 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38787.1 - 6.8e-20 71.2 6.4 0.00041 20.6 0.0 7.7 5 2 3 8 8 8 4 Anaphase-promoting complex subunit 4 WD40 domain RAB3GAP2_N PF14655.6 EGC38787.1 - 6.3e-05 22.4 1.0 0.18 11.0 0.1 3.6 3 0 0 3 3 3 2 Rab3 GTPase-activating protein regulatory subunit N-terminus AAA_21 PF13304.6 EGC38789.1 - 4.5e-12 46.4 0.1 1.2e-11 45.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain, putative AbiEii toxin, Type IV TA system NPV_P10 PF05531.12 EGC38789.1 - 0.55 10.7 1.9 0.92 10.0 0.3 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Phage_GP20 PF06810.11 EGC38789.1 - 0.92 9.3 11.7 0.32 10.8 1.3 2.7 2 0 0 2 2 2 0 Phage minor structural protein GP20 BLOC1_2 PF10046.9 EGC38789.1 - 1.9 8.8 6.7 0.39 11.1 0.9 2.8 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AbiJ_NTD4 PF18863.1 EGC38789.1 - 8.7 6.8 19.6 0.054 14.0 5.5 3.3 2 1 0 2 2 2 0 AbiJ N-terminal domain 4 COG4 PF08318.12 EGC38790.1 - 1.3e-12 47.4 3.9 1.3e-12 47.4 3.9 3.5 3 2 1 4 4 4 1 COG4 transport protein DIL PF01843.19 EGC38790.1 - 0.00088 19.5 0.3 0.00088 19.5 0.3 2.6 3 0 0 3 3 3 1 DIL domain vWF_A PF12450.8 EGC38790.1 - 0.026 14.4 0.0 0.11 12.5 0.0 2.1 1 0 0 1 1 1 0 von Willebrand factor DUF4834 PF16118.5 EGC38790.1 - 4.8 8.2 21.2 4.9 8.2 2.2 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4834) FAM176 PF14851.6 EGC38790.1 - 7.3 6.2 16.3 3.3 7.4 2.2 3.3 3 0 0 3 3 3 0 FAM176 family PsbP PF01789.16 EGC38791.1 - 3.3e-07 30.6 6.2 0.35 11.0 0.2 3.5 3 0 0 3 3 3 3 PsbP SNF2_N PF00176.23 EGC38792.1 - 1.9e-61 207.7 0.9 4.4e-61 206.5 0.9 1.6 1 0 0 1 1 1 1 SNF2 family N-terminal domain Rad60-SLD PF11976.8 EGC38792.1 - 1.6e-24 85.5 4.3 1e-07 31.7 0.0 6.2 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.31 EGC38792.1 - 5.5e-19 68.6 0.0 5.5e-19 68.6 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Chromo PF00385.24 EGC38792.1 - 2.1e-13 49.9 3.0 8.1e-10 38.5 0.6 3.2 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain ubiquitin PF00240.23 EGC38792.1 - 1.4e-11 44.0 5.9 0.00039 20.1 0.2 5.8 5 0 0 5 5 5 3 Ubiquitin family SLIDE PF09111.10 EGC38792.1 - 0.00049 20.1 0.0 0.00049 20.1 0.0 4.7 4 0 0 4 4 4 1 SLIDE CHDCT2 PF08074.11 EGC38792.1 - 0.028 14.6 0.0 0.028 14.6 0.0 4.3 4 0 0 4 4 4 0 CHDCT2 (NUC038) domain Lipase_3 PF01764.25 EGC38793.1 - 2.5e-13 50.1 0.0 1e-12 48.1 0.0 2.0 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.8 EGC38793.1 - 0.0032 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.7 EGC38793.1 - 0.2 12.2 0.0 0.26 11.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ras PF00071.22 EGC38794.1 - 6.2e-61 204.7 0.0 7.2e-61 204.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38794.1 - 1.2e-20 74.0 0.0 1.9e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38794.1 - 1.1e-08 34.8 0.0 1.2e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC38794.1 - 1.2e-06 28.2 0.1 9.6e-06 25.3 0.1 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC38794.1 - 2.4e-05 24.3 0.7 0.082 12.8 0.0 2.5 1 1 2 3 3 3 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC38794.1 - 0.00013 22.1 0.0 0.0002 21.4 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC38794.1 - 0.0082 15.7 0.2 0.056 13.0 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B Septin PF00735.18 EGC38794.1 - 0.02 14.1 0.0 0.046 13.0 0.0 1.6 1 0 0 1 1 1 0 Septin ATP_bind_1 PF03029.17 EGC38794.1 - 0.029 14.1 1.2 0.3 10.8 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein TPP_enzyme_M PF00205.22 EGC38794.1 - 0.078 12.7 0.0 0.38 10.5 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain LRAT PF04970.13 EGC38796.1 - 0.0045 17.3 1.3 0.0045 17.3 1.3 2.5 2 0 0 2 2 2 1 Lecithin retinol acyltransferase Potex_coat PF06184.11 EGC38797.1 - 0.094 12.3 0.0 16 5.1 0.0 2.3 2 0 0 2 2 2 0 Potexvirus coat protein DPBB_1 PF03330.18 EGC38797.1 - 0.24 11.7 1.1 4.3 7.7 1.1 2.5 1 1 0 1 1 1 0 Lytic transglycolase Aminotran_5 PF00266.19 EGC38798.1 - 1.2e-05 24.4 0.0 1.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Chromo PF00385.24 EGC38799.1 - 1.2e-14 53.9 2.2 1.4e-14 53.7 2.2 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGC38799.1 - 0.044 13.9 0.2 0.063 13.4 0.2 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Peptidase_M17 PF00883.21 EGC38800.1 - 1.1e-119 399.3 0.1 1.5e-119 398.9 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.17 EGC38800.1 - 5.1e-23 81.3 0.1 9.4e-23 80.4 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain YtxH PF12732.7 EGC38801.1 - 0.02 15.4 6.0 0.34 11.5 1.3 3.2 2 1 0 2 2 2 0 YtxH-like protein Unstab_antitox PF09720.10 EGC38801.1 - 0.041 13.9 0.1 0.099 12.7 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component WXG100 PF06013.12 EGC38801.1 - 0.056 13.7 0.3 4.1 7.7 0.1 3.3 2 1 0 2 2 2 0 Proteins of 100 residues with WXG DUF948 PF06103.11 EGC38801.1 - 4.6 7.6 9.2 1.7 8.9 2.5 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) AI-2E_transport PF01594.16 EGC38801.1 - 5.3 6.1 4.8 8.7 5.4 0.0 2.8 2 1 2 4 4 4 0 AI-2E family transporter Presenilin PF01080.17 EGC38801.1 - 8.6 5.0 7.2 11 4.6 7.2 1.2 1 0 0 1 1 1 0 Presenilin DUF2013 PF09431.10 EGC38803.1 - 1.2e-18 67.6 1.3 1.2e-18 67.6 1.3 2.7 3 1 0 3 3 3 1 Protein of unknown function (DUF2013) Serine_rich PF08824.10 EGC38803.1 - 0.01 15.8 0.3 0.23 11.5 0.0 2.4 1 1 1 2 2 2 0 Serine rich protein interaction domain Receptor_IA-2 PF11548.8 EGC38803.1 - 0.12 12.4 0.6 0.29 11.1 0.1 1.8 2 0 0 2 2 2 0 Protein-tyrosine phosphatase receptor IA-2 TIG PF01833.24 EGC38804.1 - 3.3e-30 104.0 51.9 5.4e-10 39.2 1.5 8.2 7 1 1 8 8 8 7 IPT/TIG domain Choline_transpo PF04515.12 EGC38805.1 - 1.4e-76 257.8 33.3 1.4e-76 257.8 33.3 2.2 2 1 1 3 3 3 1 Plasma-membrane choline transporter DUF2556 PF10831.8 EGC38805.1 - 0.06 13.3 0.1 0.06 13.3 0.1 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2556) Yip1 PF04893.17 EGC38805.1 - 1.9 8.2 39.1 0.9 9.2 1.1 4.6 3 1 0 4 4 4 0 Yip1 domain CPP1-like PF11833.8 EGC38805.1 - 6.6 6.3 11.8 2.6 7.6 0.4 3.2 3 0 0 3 3 3 0 Protein CHAPERONE-LIKE PROTEIN OF POR1-like Sec1 PF00995.23 EGC38806.1 - 6.7e-117 392.1 11.0 8e-117 391.8 11.0 1.1 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.20 EGC38806.1 - 0.073 13.5 0.0 0.62 10.5 0.0 2.6 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain MFS_1 PF07690.16 EGC38807.1 - 0.0056 15.6 50.7 0.29 10.0 14.0 3.6 1 1 0 2 2 2 2 Major Facilitator Superfamily NrsF PF06532.11 EGC38808.1 - 0.0022 17.8 5.0 0.11 12.1 0.1 3.2 2 1 1 3 3 3 2 Negative regulator of sigma F PS_Dcarbxylase PF02666.15 EGC38808.1 - 0.014 14.9 9.4 0.86 9.1 0.0 4.2 4 0 0 4 4 4 0 Phosphatidylserine decarboxylase DUF1345 PF07077.11 EGC38808.1 - 0.044 13.5 5.6 1.7 8.3 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1345) Shisa PF13908.6 EGC38808.1 - 0.27 11.5 9.4 0.26 11.5 0.3 3.6 2 2 2 4 4 4 0 Wnt and FGF inhibitory regulator DUF898 PF05987.13 EGC38808.1 - 0.47 9.4 8.8 2.4 7.1 8.7 2.2 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF4131 PF13567.6 EGC38808.1 - 0.65 9.6 12.1 2.7 7.6 0.6 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF4131) zf-RING_2 PF13639.6 EGC38809.1 - 3.7e-10 40.0 12.1 3.7e-10 40.0 12.1 1.7 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC38809.1 - 4.4e-07 29.7 8.6 8.7e-07 28.7 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC38809.1 - 9.5e-07 28.6 12.4 1.6e-06 27.8 11.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38809.1 - 2.4e-06 27.7 8.4 9.5e-06 25.8 8.1 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain TFIIA PF03153.13 EGC38809.1 - 2.5e-06 27.8 22.5 3.3e-06 27.4 22.5 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.25 EGC38809.1 - 2.8e-06 27.1 14.0 6.3e-06 26.0 14.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC38809.1 - 0.002 18.0 12.6 0.0043 17.0 12.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC38809.1 - 0.0023 17.7 8.2 0.011 15.6 8.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 ATP-synt_8 PF00895.20 EGC38809.1 - 0.027 14.9 0.4 0.027 14.9 0.4 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 Asp-B-Hydro_N PF05279.11 EGC38809.1 - 0.057 13.5 27.1 0.012 15.7 18.9 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region zf-RING_10 PF16685.5 EGC38809.1 - 0.1 12.8 8.5 0.22 11.7 8.5 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-ANAPC11 PF12861.7 EGC38809.1 - 0.11 12.6 5.5 0.31 11.1 5.5 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGC38809.1 - 0.17 11.9 8.6 0.76 9.9 8.6 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC38809.1 - 0.22 11.7 12.8 0.64 10.2 12.8 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Zn_ribbon_17 PF17120.5 EGC38809.1 - 0.42 10.3 9.4 0.77 9.4 9.4 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type CAF-1_p150 PF11600.8 EGC38809.1 - 0.49 10.1 33.8 0.036 13.8 27.3 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Ndc1_Nup PF09531.10 EGC38809.1 - 0.58 8.8 13.0 0.93 8.1 13.0 1.4 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup zf-RING_11 PF17123.5 EGC38809.1 - 0.76 9.6 8.1 1.5 8.6 8.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger AAA_23 PF13476.6 EGC38809.1 - 1.3 9.5 17.3 0.65 10.5 12.7 2.1 2 0 0 2 2 2 0 AAA domain Ncstrn_small PF18266.1 EGC38810.1 - 1.6e-43 148.7 0.3 4.6e-43 147.2 0.1 1.9 2 0 0 2 2 2 1 Nicastrin small lobe Nicastrin PF05450.15 EGC38810.1 - 5.2e-34 117.7 0.3 9.9e-34 116.8 0.3 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.17 EGC38810.1 - 1.2e-08 34.9 0.0 2.1e-08 34.1 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 GCS PF03074.16 EGC38811.1 - 1.4e-166 554.4 0.7 2.1e-166 553.8 0.7 1.3 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1199 PF06712.11 EGC38811.1 - 0.13 12.3 1.2 0.46 10.5 1.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) DHR-2 PF06920.13 EGC38812.1 - 6.3e-92 308.9 16.5 6.3e-92 308.9 16.5 3.3 3 1 0 3 3 3 1 Dock homology region 2 DOCK_N PF16172.5 EGC38812.1 - 8.2e-70 235.6 2.3 2.1e-69 234.3 2.3 1.7 1 0 0 1 1 1 1 DOCK N-terminus DOCK-C2 PF14429.6 EGC38812.1 - 1.8e-43 148.6 4.4 8.1e-43 146.5 1.1 3.1 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.28 EGC38812.1 - 8e-10 38.2 0.0 1.8e-09 37.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC38812.1 - 2.6e-07 30.4 0.0 5.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC38812.1 - 0.0003 20.4 0.0 0.00068 19.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pentapeptide PF00805.22 EGC38813.1 - 9.8e-24 82.6 20.9 5.7e-11 41.8 4.0 4.7 2 2 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.6 EGC38813.1 - 1.8e-18 66.5 23.0 5.1e-10 39.4 7.1 3.4 3 0 0 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.6 EGC38813.1 - 2.8e-17 62.6 19.1 6.8e-08 32.5 5.4 4.5 2 2 2 4 4 4 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.22 EGC38813.1 - 2e-14 53.7 0.0 5.5e-14 52.3 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Pribosyltran PF00156.27 EGC38814.1 - 8.1e-25 87.2 0.0 1e-24 86.9 0.0 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGC38814.1 - 2.5e-07 30.3 0.0 1.9e-05 24.2 0.1 2.0 2 0 0 2 2 2 2 Uracil phosphoribosyltransferase PRTase_2 PF15609.6 EGC38814.1 - 1.2e-06 28.2 0.0 2e-06 27.4 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase DHHA1 PF02272.19 EGC38814.1 - 0.066 13.6 0.4 0.13 12.7 0.4 1.5 1 0 0 1 1 1 0 DHHA1 domain Mur_ligase_C PF02875.21 EGC38814.1 - 0.096 13.0 0.0 0.25 11.6 0.0 1.8 1 1 0 1 1 1 0 Mur ligase family, glutamate ligase domain PAP2 PF01569.21 EGC38815.1 - 1.7e-22 79.6 3.5 1.7e-22 79.6 3.5 1.6 2 0 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGC38815.1 - 0.052 13.2 4.7 0.35 10.6 4.7 2.3 1 1 0 1 1 1 0 PAP2 superfamily Bax1-I PF01027.20 EGC38815.1 - 9.1 6.0 14.1 1.4e+02 2.1 14.2 2.2 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Yae1_N PF09811.9 EGC38816.1 - 8.7e-10 38.1 0.6 1.3e-09 37.6 0.6 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Ribosomal_L12 PF00542.19 EGC38816.1 - 0.13 12.6 0.0 0.78 10.1 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein L7/L12 C-terminal domain HTH_41 PF14502.6 EGC38817.1 - 0.086 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain PCI PF01399.27 EGC38818.1 - 1.1e-13 51.6 2.5 1.7e-13 51.0 1.0 2.1 2 0 0 2 2 2 1 PCI domain DUF2250 PF10007.9 EGC38818.1 - 0.27 11.4 1.5 12 6.1 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RRM_1 PF00076.22 EGC38819.1 - 0.0011 18.8 0.3 0.0031 17.3 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGC38820.1 - 1.8e-14 53.3 0.0 3.1e-14 52.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.11 EGC38820.1 - 0.028 14.5 0.0 0.058 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif DUF4651 PF15513.6 EGC38820.1 - 0.058 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) SUR7 PF06687.12 EGC38821.1 - 3.5e-05 23.5 8.0 3.5e-05 23.5 8.0 2.5 2 1 1 3 3 3 1 SUR7/PalI family DUF4064 PF13273.6 EGC38821.1 - 0.0001 22.5 9.8 0.014 15.7 5.4 2.7 2 1 0 2 2 2 2 Protein of unknown function (DUF4064) Peptidase_U4 PF03419.13 EGC38821.1 - 0.051 12.9 8.7 0.0094 15.3 5.2 1.5 2 0 0 2 2 2 0 Sporulation factor SpoIIGA Meckelin PF09773.9 EGC38821.1 - 0.069 11.2 1.8 0.1 10.7 1.8 1.1 1 0 0 1 1 1 0 Meckelin (Transmembrane protein 67) PGG PF13962.6 EGC38821.1 - 0.43 10.4 7.0 1.2 9.0 2.8 2.3 2 0 0 2 2 2 0 Domain of unknown function Peptidase_A22B PF04258.13 EGC38821.1 - 0.69 9.4 6.7 0.52 9.8 3.8 1.8 1 1 1 2 2 2 0 Signal peptide peptidase DUF3488 PF11992.8 EGC38821.1 - 2.8 6.8 7.3 1.2 8.0 4.8 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3488) DUF4293 PF14126.6 EGC38821.1 - 3.5 7.8 9.0 0.45 10.8 4.4 1.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) FKBP_C PF00254.28 EGC38822.1 - 6.2e-30 103.4 0.0 7.7e-30 103.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRM_1 PF00076.22 EGC38823.1 - 3.9e-48 161.1 1.2 1.6e-20 72.7 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC38823.1 - 3.5e-08 33.5 0.2 0.0039 17.3 0.0 3.5 3 1 0 3 3 3 2 RNA recognition motif RRM_occluded PF16842.5 EGC38823.1 - 7.2e-06 25.8 0.0 1.7 8.6 0.0 3.4 3 0 0 3 3 3 3 Occluded RNA-recognition motif Nup35_RRM_2 PF14605.6 EGC38823.1 - 0.031 14.3 0.4 9.6 6.3 0.0 2.8 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Linker_histone PF00538.19 EGC38824.1 - 1.4e-22 79.8 0.1 3.3e-22 78.6 0.1 1.6 1 0 0 1 1 1 1 linker histone H1 and H5 family PaaX PF07848.12 EGC38824.1 - 0.018 15.3 0.0 0.029 14.6 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein DUF1247 PF06851.11 EGC38824.1 - 0.14 12.0 0.0 0.18 11.7 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1247) MCM6_C PF18263.1 EGC38824.1 - 0.15 12.3 0.0 0.23 11.7 0.0 1.3 1 0 0 1 1 1 0 MCM6 C-terminal winged-helix domain HemN_C PF06969.16 EGC38824.1 - 0.16 12.1 0.0 0.5 10.5 0.0 1.7 1 1 0 1 1 1 0 HemN C-terminal domain DUF4680 PF15730.5 EGC38824.1 - 1.4 9.2 11.5 2.9 8.2 11.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4680) Mucin PF01456.17 EGC38824.1 - 4.8 7.2 17.6 3.8 7.5 1.0 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein FAD_binding_6 PF00970.24 EGC38825.1 - 1.4e-33 115.2 0.0 2.5e-33 114.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.21 EGC38825.1 - 1.2e-32 112.7 0.0 2.4e-32 111.8 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.12 EGC38825.1 - 7.8e-07 29.3 0.2 0.00029 21.0 0.0 2.4 3 0 0 3 3 3 2 Ferric reductase NAD binding domain SURF6 PF04935.12 EGC38826.1 - 1e-22 80.9 70.5 2.9e-22 79.5 58.4 3.0 1 1 1 2 2 2 1 Surfeit locus protein 6 DUF3439 PF11921.8 EGC38826.1 - 0.0027 17.7 7.5 0.0076 16.2 7.5 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC38826.1 - 0.21 11.6 12.2 0.4 10.7 12.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dapper PF15268.6 EGC38826.1 - 1.4 7.7 39.9 1.9 7.3 39.9 1.1 1 0 0 1 1 1 0 Dapper Glyco_hydro_18 PF00704.28 EGC38828.1 - 2.1e-16 60.6 2.9 2.6e-16 60.2 2.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 DDE_Tnp_1_7 PF13843.6 EGC38829.1 - 3.4e-05 23.3 0.0 0.00015 21.2 0.0 1.9 1 1 0 1 1 1 1 Transposase IS4 Peptidase_M76 PF09768.9 EGC38830.1 - 0.045 13.5 0.5 0.099 12.4 0.5 1.6 1 0 0 1 1 1 0 Peptidase M76 family Porphobil_deam PF01379.20 EGC38831.1 - 0.0095 15.5 0.4 4.5 6.7 0.0 4.0 1 1 5 6 6 6 2 Porphobilinogen deaminase, dipyromethane cofactor binding domain B_solenoid_ydck PF18836.1 EGC38831.1 - 0.016 15.1 0.0 9.2e+02 -0.0 0.0 6.3 8 0 0 8 8 8 0 Beta solenoid repeat from YDCK LRR_4 PF12799.7 EGC38831.1 - 0.027 14.9 0.5 1.8 9.1 0.1 3.4 1 1 3 4 4 4 0 Leucine Rich repeats (2 copies) CRIC_ras_sig PF10534.9 EGC38831.1 - 0.11 12.6 0.1 2.8 8.2 0.0 2.8 1 1 3 4 4 4 0 Connector enhancer of kinase suppressor of ras Ion_trans_N PF08412.10 EGC38831.1 - 0.55 9.9 2.7 82 2.9 0.0 4.6 8 0 0 8 8 8 0 Ion transport protein N-terminal Vma12 PF11712.8 EGC38832.1 - 4.6e-13 49.4 0.1 4.6e-13 49.4 0.1 2.5 2 2 1 3 3 3 1 Endoplasmic reticulum-based factor for assembly of V-ATPase MFS_2 PF13347.6 EGC38832.1 - 6.3e-05 21.7 0.0 8.2e-05 21.3 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein DUF2992 PF11208.8 EGC38832.1 - 0.0011 19.3 0.0 0.0011 19.3 0.0 2.8 3 1 1 4 4 4 1 Protein of unknown function (DUF2992) DUF2391 PF09622.10 EGC38832.1 - 0.052 12.9 0.1 0.084 12.2 0.1 1.3 1 0 0 1 1 1 0 Putative integral membrane protein (DUF2391) DnaI_N PF07319.11 EGC38832.1 - 0.66 10.7 11.2 1.5 9.5 0.3 3.1 3 0 0 3 3 3 0 Primosomal protein DnaI N-terminus BRCT PF00533.26 EGC38833.1 - 1.1e-08 35.3 1.1 1.8e-07 31.4 0.2 3.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC38833.1 - 1.5e-06 28.5 1.5 1e-05 25.8 0.3 3.0 2 0 0 2 2 2 1 BRCT domain, a BRCA1 C-terminus domain DUF4207 PF13904.6 EGC38833.1 - 0.0085 15.8 18.1 0.0085 15.8 18.1 3.2 3 0 0 3 3 3 2 Domain of unknown function (DUF4207) DUF1477 PF07346.11 EGC38833.1 - 0.052 13.8 1.5 0.27 11.5 0.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1477) RRM_1 PF00076.22 EGC38833.1 - 0.053 13.4 0.3 0.21 11.5 0.3 2.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FNIP PF05725.12 EGC38834.1 - 4.2e-30 103.6 10.9 3.6e-14 52.6 0.3 3.0 2 1 1 3 3 3 3 FNIP Repeat LRR_1 PF00560.33 EGC38834.1 - 0.00042 20.5 1.0 1.1 10.1 0.1 3.3 2 1 2 4 4 4 2 Leucine Rich Repeat zf-RVT PF13966.6 EGC38835.1 - 3.3e-05 24.5 0.7 7e-05 23.5 0.7 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GATA PF00320.27 EGC38835.1 - 0.0021 17.6 0.0 0.0054 16.3 0.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.31 EGC38836.1 - 6.5e-55 183.1 24.2 3.6e-16 59.1 0.0 6.4 6 0 0 6 6 6 5 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC38836.1 - 2.2e-45 152.7 22.8 2.5e-13 50.0 0.3 7.1 2 1 4 6 6 6 5 Myb-like DNA-binding domain SLIDE PF09111.10 EGC38836.1 - 4.2e-05 23.5 23.6 2.4 8.2 0.0 7.3 5 1 2 7 7 7 4 SLIDE TSNAXIP1_N PF15739.5 EGC38836.1 - 0.0069 16.8 2.7 0.0069 16.8 2.7 3.3 3 0 0 3 3 3 1 Translin-associated factor X-interacting N-terminus DUF3439 PF11921.8 EGC38836.1 - 0.11 12.5 8.1 0.23 11.4 8.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Rap1_C PF11626.8 EGC38836.1 - 0.25 11.4 10.8 0.67 10.1 0.6 4.4 2 1 0 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Atg29_N PF18388.1 EGC38836.1 - 3.1 7.7 5.3 4.3 7.2 0.5 3.1 3 0 0 3 3 3 0 Atg29 N-terminal domain Mucin PF01456.17 EGC38836.1 - 3.2 7.7 16.8 5.8 6.9 16.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein adh_short PF00106.25 EGC38837.1 - 1.1e-46 158.8 0.0 1.4e-46 158.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC38837.1 - 2.8e-31 108.9 0.0 3.4e-31 108.6 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.21 EGC38837.1 - 2.2e-06 27.3 0.0 4.9e-06 26.2 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.10 EGC38837.1 - 7e-06 25.6 0.0 9.7e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.10 EGC38837.1 - 9.6e-06 25.6 0.0 1.4e-05 25.1 0.0 1.2 1 0 0 1 1 1 1 KR domain GDP_Man_Dehyd PF16363.5 EGC38837.1 - 1.1e-05 25.0 0.1 2.1e-05 24.1 0.1 1.5 1 1 0 1 1 1 1 GDP-mannose 4,6 dehydratase RmlD_sub_bind PF04321.17 EGC38837.1 - 0.025 13.7 0.0 0.054 12.6 0.0 1.5 2 0 0 2 2 2 0 RmlD substrate binding domain Pkinase_Tyr PF07714.17 EGC38838.1 - 2.3e-21 76.3 0.0 2.7e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC38838.1 - 2.3e-14 53.4 0.0 3e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PGI PF00342.19 EGC38839.1 - 6.2e-245 813.3 0.8 7e-245 813.1 0.8 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Attacin_N PF03768.15 EGC38839.1 - 0.088 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 Attacin, N-terminal region Ephrin_rec_like PF07699.13 EGC38840.1 - 0.024 14.4 2.8 0.035 13.9 1.1 2.3 2 0 0 2 2 2 0 Putative ephrin-receptor like His_Phos_2 PF00328.22 EGC38841.1 - 1e-25 90.9 0.0 1.5e-20 73.9 0.0 2.1 2 0 0 2 2 2 2 Histidine phosphatase superfamily (branch 2) V-SNARE PF05008.15 EGC38842.1 - 3.7e-05 24.0 2.9 3.7e-05 24.0 2.9 3.2 2 2 1 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.8 EGC38842.1 - 0.00024 21.3 2.3 0.00045 20.5 0.9 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus ABC2_membrane_3 PF12698.7 EGC38842.1 - 0.0012 18.0 0.1 0.0017 17.5 0.1 1.3 1 0 0 1 1 1 1 ABC-2 family transporter protein RIFIN PF02009.16 EGC38842.1 - 0.0022 18.0 9.8 0.0041 17.0 9.8 1.4 1 1 0 1 1 1 1 Rifin SNARE PF05739.19 EGC38842.1 - 0.0034 17.4 4.1 0.0034 17.4 4.1 2.6 4 0 0 4 4 2 1 SNARE domain DUF4199 PF13858.6 EGC38842.1 - 0.0059 17.0 2.5 0.0059 17.0 2.5 1.8 2 1 0 2 2 2 1 Protein of unknown function (DUF4199) Otopetrin PF03189.13 EGC38842.1 - 0.0094 14.8 0.7 0.013 14.4 0.6 1.3 1 1 0 1 1 1 1 Otopetrin Orf78 PF06024.12 EGC38842.1 - 0.011 16.0 2.0 0.011 16.0 2.0 2.2 1 1 1 2 2 2 0 Orf78 (ac78) DUF4083 PF13314.6 EGC38842.1 - 0.016 15.1 2.6 0.048 13.6 2.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) DUF2207 PF09972.9 EGC38842.1 - 0.018 13.8 2.1 0.025 13.4 1.7 1.4 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) MtrF PF09472.10 EGC38842.1 - 0.022 14.1 1.9 0.04 13.3 1.9 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) DUF3533 PF12051.8 EGC38842.1 - 0.04 12.8 1.1 0.056 12.4 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Pex24p PF06398.11 EGC38842.1 - 0.045 12.7 0.0 0.048 12.6 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin Sec20 PF03908.13 EGC38842.1 - 0.11 12.4 5.4 0.098 12.6 2.9 2.2 2 1 0 2 2 2 0 Sec20 GP41 PF00517.17 EGC38842.1 - 0.21 11.5 3.8 0.48 10.3 3.8 1.9 1 1 0 1 1 1 0 Retroviral envelope protein TMPIT PF07851.13 EGC38842.1 - 0.26 10.5 8.7 0.9 8.7 2.2 2.2 2 0 0 2 2 2 0 TMPIT-like protein Nup54 PF13874.6 EGC38842.1 - 0.34 11.0 16.7 3.8 7.6 2.5 3.2 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 DUF2730 PF10805.8 EGC38842.1 - 0.42 10.7 9.9 2.4 8.3 3.8 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF2730) FeoB_associated PF12669.7 EGC38842.1 - 0.46 10.9 3.4 0.82 10.1 3.4 1.3 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein DUF2116 PF09889.9 EGC38842.1 - 1 9.4 2.9 3.5 7.7 2.9 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) EMP24_GP25L PF01105.24 EGC38842.1 - 1.2 9.0 10.1 2.5 8.0 2.3 3.2 2 1 1 3 3 3 0 emp24/gp25L/p24 family/GOLD MCU PF04678.13 EGC38842.1 - 1.7 8.7 9.9 0.66 10.1 5.4 2.0 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Prominin PF05478.11 EGC38842.1 - 2.7 5.8 13.1 6.4 4.6 7.4 2.2 1 1 0 2 2 2 0 Prominin Synaptobrevin PF00957.21 EGC38842.1 - 2.7 7.8 16.5 0.026 14.3 6.2 2.6 3 0 0 3 3 3 0 Synaptobrevin EssA PF10661.9 EGC38842.1 - 3.6 7.4 10.9 11 5.8 10.8 1.9 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA DLP_helical PF18709.1 EGC38842.1 - 3.8 6.6 14.0 0.36 10.0 6.2 2.5 2 1 0 2 2 2 0 Dynamin-like helical domain Lebercilin PF15619.6 EGC38842.1 - 4.8 6.8 20.8 0.98 9.0 9.2 2.3 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Cir_Bir_Yir PF06022.11 EGC38842.1 - 8.8 5.7 7.2 66 2.9 7.2 2.1 1 1 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir CsbD PF05532.12 EGC38843.1 - 7.8e-05 22.5 2.4 0.00018 21.4 1.8 1.8 2 0 0 2 2 2 1 CsbD-like Cloacin_immun PF03513.14 EGC38843.1 - 5.5 7.4 6.4 18 5.7 0.3 2.8 2 1 1 3 3 3 0 Cloacin immunity protein APC1_C PF18122.1 EGC38844.1 - 8.6e-31 107.1 0.4 3.6e-30 105.1 0.4 2.2 1 0 0 1 1 1 1 Anaphase-promoting complex sub unit 1 C-terminal domain ANAPC1 PF12859.7 EGC38844.1 - 1.8e-07 31.8 10.6 3.2e-06 27.7 0.0 4.7 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 1 PC_rep PF01851.22 EGC38844.1 - 3.2e-06 27.3 2.4 0.086 13.3 0.1 5.3 5 0 0 5 5 5 2 Proteasome/cyclosome repeat LSM PF01423.22 EGC38845.1 - 9.5e-19 66.9 0.6 1.4e-18 66.4 0.6 1.2 1 0 0 1 1 1 1 LSM domain Hfq PF17209.3 EGC38845.1 - 0.067 12.8 0.1 0.11 12.2 0.1 1.3 1 0 0 1 1 1 0 Hfq protein DUF2956 PF11169.8 EGC38847.1 - 3.7 7.8 14.2 4.1 7.7 14.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Sec62 PF03839.16 EGC38847.1 - 7.7 6.0 13.4 8 5.9 13.4 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 FNIP PF05725.12 EGC38848.1 - 1.2e-14 54.2 7.6 1.7e-08 34.5 0.7 9.4 7 3 3 10 10 10 7 FNIP Repeat MitoNEET_N PF10660.9 EGC38848.1 - 0.1 12.6 0.5 0.97 9.5 0.2 2.8 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus ERM PF00769.19 EGC38849.1 - 3.1e-05 23.9 14.5 3.3e-05 23.9 3.0 2.1 2 0 0 2 2 2 2 Ezrin/radixin/moesin family DUF4686 PF15742.5 EGC38849.1 - 0.032 13.4 23.0 0.05 12.7 10.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4686) F420_oxidored PF03807.17 EGC38849.1 - 0.047 14.3 0.3 0.1 13.2 0.3 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent HutD PF05962.11 EGC38849.1 - 0.097 12.6 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 HutD DUF1664 PF07889.12 EGC38849.1 - 0.35 10.9 13.7 0.97 9.5 1.3 3.9 2 2 1 4 4 4 0 Protein of unknown function (DUF1664) Laminin_II PF06009.12 EGC38849.1 - 0.44 10.6 7.9 0.46 10.5 0.1 3.1 2 2 2 4 4 4 0 Laminin Domain II Cep57_MT_bd PF06657.13 EGC38849.1 - 0.89 10.0 12.5 1.4 9.4 0.7 4.1 2 2 1 4 4 4 0 Centrosome microtubule-binding domain of Cep57 DUF349 PF03993.12 EGC38849.1 - 0.98 9.8 7.1 7.3 7.0 0.0 3.3 3 2 0 3 3 3 0 Domain of Unknown Function (DUF349) DUF2203 PF09969.9 EGC38849.1 - 1.9 9.2 10.6 3.1 8.6 1.3 2.6 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) APG6_N PF17675.1 EGC38849.1 - 6.9 7.2 23.6 3.4 8.2 2.1 3.1 2 2 1 3 3 3 0 Apg6 coiled-coil region DUF4795 PF16043.5 EGC38849.1 - 7 6.2 17.7 0.16 11.6 1.7 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4795) DUF16 PF01519.16 EGC38849.1 - 7.5 7.1 21.1 0.19 12.2 3.8 3.6 1 1 2 3 3 3 0 Protein of unknown function DUF16 Pkinase_Tyr PF07714.17 EGC38851.1 - 7.2e-59 199.2 0.4 3.5e-58 196.9 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.25 EGC38851.1 - 5.2e-53 180.1 2.6 6.2e-52 176.6 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_fungal PF17667.1 EGC38851.1 - 3.3e-07 29.4 0.1 4.8e-07 28.9 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase Cbl_N2 PF02761.14 EGC38851.1 - 1.4e-05 25.7 0.9 1.4e-05 25.7 0.9 2.6 3 0 0 3 3 3 1 CBL proto-oncogene N-terminus, EF hand-like domain SH2 PF00017.24 EGC38851.1 - 1.9e-05 24.7 0.0 5.1e-05 23.3 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Presenilin PF01080.17 EGC38851.1 - 0.098 11.4 0.7 0.12 11.1 0.7 1.2 1 0 0 1 1 1 0 Presenilin CCSAP PF15748.5 EGC38851.1 - 0.59 10.3 8.9 0.94 9.6 8.9 1.3 1 0 0 1 1 1 0 Centriole, cilia and spindle-associated Peptidase_M16_C PF05193.21 EGC38852.1 - 2.5e-17 63.5 0.0 8.2e-16 58.5 0.0 3.2 2 1 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC38852.1 - 2.1e-08 34.3 0.1 1.4e-07 31.6 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SF3a60_bindingd PF12108.8 EGC38852.1 - 0.16 11.9 1.4 17 5.4 0.1 3.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain TMEM208_SND2 PF05620.11 EGC38853.1 - 0.03 14.1 1.0 0.045 13.5 1.0 1.2 1 0 0 1 1 1 0 SRP-independent targeting protein 2/TMEM208 CEP63 PF17045.5 EGC38853.1 - 0.055 13.4 0.1 0.56 10.1 0.0 1.9 2 0 0 2 2 2 0 Centrosomal protein of 63 kDa PMT_4TMC PF16192.5 EGC38853.1 - 0.11 12.1 3.5 0.22 11.1 3.5 1.6 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase AI-2E_transport PF01594.16 EGC38854.1 - 0.0071 15.5 0.5 0.022 13.9 0.5 1.8 1 0 0 1 1 1 1 AI-2E family transporter RYDR_ITPR PF01365.21 EGC38854.1 - 0.047 13.1 0.3 0.23 10.8 0.0 2.3 2 1 0 2 2 2 0 RIH domain ArdA PF07275.11 EGC38855.1 - 0.013 16.1 0.5 0.015 15.9 0.5 1.1 1 0 0 1 1 1 0 Antirestriction protein (ArdA) Profilin PF00235.19 EGC38855.1 - 0.021 15.1 0.1 0.025 14.9 0.1 1.2 1 0 0 1 1 1 0 Profilin NS3_envE PF02723.14 EGC38855.1 - 0.038 14.1 0.3 0.069 13.2 0.3 1.5 1 0 0 1 1 1 0 Non-structural protein NS3/Small envelope protein E Zn_peptidase_2 PF04298.12 EGC38855.1 - 0.067 12.6 0.1 0.097 12.1 0.1 1.3 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase His_Me_b4a2 PF18275.1 EGC38855.1 - 0.37 10.9 4.5 0.37 10.9 0.5 2.2 2 0 0 2 2 2 0 His-Me finger endonuclease beta4-alpha2 domain FNIP PF05725.12 EGC38856.1 - 2.1e-151 491.9 57.4 1e-17 64.0 0.8 13.0 5 3 2 13 13 13 12 FNIP Repeat Peptidase_S78 PF04586.17 EGC38856.1 - 0.0072 16.5 0.0 25 5.0 0.0 5.5 4 3 3 7 7 7 1 Caudovirus prohead serine protease LRR_1 PF00560.33 EGC38856.1 - 0.44 11.3 18.2 89 4.3 0.3 9.1 5 3 0 5 5 5 0 Leucine Rich Repeat Lactamase_B_2 PF12706.7 EGC38857.1 - 3.7e-35 121.3 0.0 4.8e-35 120.9 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.6 EGC38857.1 - 4.6e-14 52.6 0.0 6.1e-14 52.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.27 EGC38857.1 - 0.0018 18.3 0.1 0.0041 17.2 0.0 1.6 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily TFIIB PF00382.19 EGC38858.1 - 7.2e-41 138.1 0.1 1.3e-23 82.8 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.12 EGC38858.1 - 4.9e-12 45.2 1.5 8.1e-12 44.5 1.5 1.4 1 0 0 1 1 1 1 TFIIB zinc-binding HTH_Tnp_ISL3 PF13542.6 EGC38858.1 - 0.00038 19.8 0.0 0.41 10.1 0.0 2.9 2 0 0 2 2 2 2 Helix-turn-helix domain of transposase family ISL3 Cyclin_C PF02984.19 EGC38858.1 - 0.00063 19.8 2.9 1 9.5 0.2 3.1 2 1 1 3 3 3 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.16 EGC38858.1 - 0.0012 18.3 0.0 0.36 10.4 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 RB_B PF01857.20 EGC38858.1 - 0.0018 18.3 0.1 0.0086 16.1 0.1 2.1 2 1 0 2 2 2 1 Retinoblastoma-associated protein B domain Sigma70_r4_2 PF08281.12 EGC38858.1 - 0.0034 17.0 0.0 0.12 12.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Yippee-Mis18 PF03226.14 EGC38858.1 - 0.013 15.7 0.6 1.7 8.9 0.5 2.5 2 0 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HTH_3 PF01381.22 EGC38858.1 - 0.016 15.2 0.1 1.9 8.6 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix Rrf2 PF02082.20 EGC38858.1 - 0.02 15.2 0.1 2.6 8.5 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator SNF5 PF04855.12 EGC38858.1 - 0.049 13.4 0.1 0.14 12.0 0.0 1.7 2 0 0 2 2 2 0 SNF5 / SMARCB1 / INI1 HTH_11 PF08279.12 EGC38858.1 - 0.054 13.4 0.0 0.13 12.3 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_36 PF13730.6 EGC38858.1 - 0.056 13.4 0.1 1.5 8.9 0.0 2.9 3 0 0 3 3 3 0 Helix-turn-helix domain GntR PF00392.21 EGC38858.1 - 0.082 12.6 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_Crp_2 PF13545.6 EGC38858.1 - 0.086 12.8 0.0 12 6.0 0.0 2.8 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain Dehydratase_SU PF02287.15 EGC38858.1 - 0.14 12.3 0.2 0.57 10.3 0.0 2.0 3 0 0 3 3 3 0 Dehydratase small subunit ETF PF01012.21 EGC38859.1 - 2.2e-41 141.7 0.9 3.1e-41 141.3 0.9 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain ETF_alpha PF00766.19 EGC38859.1 - 9.2e-38 128.2 0.9 2.3e-37 126.9 0.9 1.7 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain FNIP PF05725.12 EGC38860.1 - 1.1e-154 502.4 74.3 1.6e-16 60.2 0.7 9.6 1 1 9 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.13 EGC38860.1 - 0.00034 20.9 0.1 28 5.2 0.0 6.3 3 2 4 7 7 7 1 Phage minor tail protein LRR_1 PF00560.33 EGC38860.1 - 0.11 13.1 10.5 46 5.1 0.0 7.4 3 3 2 5 5 5 0 Leucine Rich Repeat Metallophos PF00149.28 EGC38861.1 - 5.3e-30 105.4 0.9 9.3e-30 104.7 0.9 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.12 EGC38861.1 - 4.7e-24 84.5 0.3 1.1e-23 83.3 0.3 1.7 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_2 PF07719.17 EGC38861.1 - 1.1e-12 47.1 9.4 2.1e-06 27.4 1.2 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC38861.1 - 8.3e-10 38.1 15.3 4.4e-05 23.1 1.3 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.6 EGC38861.1 - 3.5e-07 30.6 2.2 2.5e-05 24.7 0.2 3.1 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38861.1 - 1e-06 28.4 6.9 2.6e-05 24.1 0.6 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC38861.1 - 4.8e-06 26.9 4.6 0.00067 20.1 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC38861.1 - 4.3e-05 24.1 0.0 0.1 13.3 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC38861.1 - 0.0002 21.0 11.2 0.077 12.7 0.2 3.5 2 1 1 3 3 3 2 TPR repeat Fis1_TPR_C PF14853.6 EGC38861.1 - 0.00021 21.3 0.4 0.00049 20.1 0.4 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.6 EGC38861.1 - 0.00083 19.6 1.2 0.022 15.1 0.2 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC38861.1 - 0.0014 18.9 3.2 0.016 15.4 0.4 2.6 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC38861.1 - 0.0014 18.5 1.2 0.059 13.4 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC38861.1 - 0.0018 19.0 0.0 0.023 15.5 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.18 EGC38861.1 - 0.18 11.9 3.8 2 8.5 1.0 2.5 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain ANAPC3 PF12895.7 EGC38861.1 - 0.49 10.6 3.8 0.54 10.5 2.2 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 FNIP PF05725.12 EGC38862.1 - 3.2e-68 225.7 44.4 3.1e-16 59.2 0.7 6.6 2 1 1 6 6 6 6 FNIP Repeat LRR_1 PF00560.33 EGC38862.1 - 6.1 7.8 8.8 2.8e+02 2.8 0.4 6.0 2 2 2 4 4 4 0 Leucine Rich Repeat Profilin PF00235.19 EGC38863.1 - 2.8e-10 40.5 0.6 3.3e-10 40.3 0.6 1.2 1 0 0 1 1 1 1 Profilin G-alpha PF00503.20 EGC38864.1 - 7.1e-101 337.9 10.9 8.2e-101 337.7 10.9 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.21 EGC38864.1 - 8.7e-14 51.3 2.0 3.6e-10 39.6 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC38864.1 - 6.2e-05 22.5 1.0 0.0053 16.1 0.2 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Roc PF08477.13 EGC38864.1 - 0.0023 18.1 0.1 1.9 8.8 0.0 2.5 2 0 0 2 2 2 2 Ras of Complex, Roc, domain of DAPkinase Tipalpha PF16753.5 EGC38864.1 - 0.011 15.6 0.7 0.1 12.4 0.1 2.3 2 0 0 2 2 2 0 TNF-alpha-Inducing protein of Helicobacter MMR_HSR1 PF01926.23 EGC38864.1 - 0.014 15.5 0.0 6.8 6.8 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SRPRB PF09439.10 EGC38864.1 - 0.029 13.8 1.4 0.85 9.0 0.0 2.9 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit AAA_29 PF13555.6 EGC38864.1 - 0.068 12.9 0.5 0.15 11.8 0.0 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain COPI_assoc PF08507.10 EGC38865.1 - 5.5e-31 107.3 12.6 6.6e-31 107.1 12.6 1.1 1 0 0 1 1 1 1 COPI associated protein MMR_HSR1 PF01926.23 EGC38867.1 - 1.2e-15 57.6 3.9 1.2e-13 51.2 0.0 3.4 3 1 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC38867.1 - 1.2e-08 34.6 0.1 2.6e-05 23.8 0.1 2.8 2 0 0 2 2 2 2 Ferrous iron transport protein B RsgA_GTPase PF03193.16 EGC38867.1 - 1.3e-05 25.2 10.7 4.8e-05 23.3 0.0 3.9 4 0 0 4 4 4 2 RsgA GTPase Dynamin_N PF00350.23 EGC38867.1 - 0.013 15.5 0.4 0.013 15.5 0.4 5.7 4 3 2 6 6 6 0 Dynamin family NOG1 PF06858.14 EGC38867.1 - 0.042 13.6 0.0 0.15 11.9 0.0 2.0 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Roc PF08477.13 EGC38867.1 - 0.26 11.5 0.1 0.26 11.5 0.1 3.7 4 0 0 4 4 4 0 Ras of Complex, Roc, domain of DAPkinase Mucin PF01456.17 EGC38867.1 - 0.39 10.7 7.7 0.67 9.9 7.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AT_hook PF02178.19 EGC38868.1 - 0.037 13.9 46.6 1.5 8.9 3.2 4.5 4 0 0 4 4 4 0 AT hook motif SVIP PF15811.5 EGC38868.1 - 1.6 9.2 12.1 0.36 11.3 7.3 2.3 2 0 0 2 2 2 0 Small VCP/p97-interacting protein APG9 PF04109.16 EGC38869.1 - 1.3e-105 354.2 4.8 1.6e-105 353.9 4.8 1.1 1 0 0 1 1 1 1 Autophagy protein Apg9 MID_MedPIWI PF18296.1 EGC38869.1 - 0.0018 18.1 2.5 0.0027 17.5 2.5 1.2 1 0 0 1 1 1 1 MID domain of medPIWI DUF2171 PF09939.9 EGC38869.1 - 0.19 12.0 0.6 11 6.4 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2171) Menin PF05053.13 EGC38869.1 - 1.1 7.5 7.0 1.6 7.0 7.0 1.1 1 0 0 1 1 1 0 Menin Ald_Xan_dh_C2 PF02738.18 EGC38870.1 - 5.4e-195 649.0 0.0 7.4e-195 648.5 0.0 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.21 EGC38870.1 - 2.1e-45 154.5 0.1 1e-44 152.3 0.0 2.0 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.17 EGC38870.1 - 1e-33 115.5 0.0 8.7e-33 112.6 0.0 2.3 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.22 EGC38870.1 - 1.8e-31 108.8 0.1 4.1e-31 107.6 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.20 EGC38870.1 - 2.3e-29 101.2 0.0 5.3e-29 100.1 0.0 1.7 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.27 EGC38870.1 - 3.2e-07 30.2 0.3 1.1e-06 28.5 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.9 EGC38870.1 - 0.17 11.7 3.3 0.22 11.4 1.5 2.1 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B Prothymosin PF03247.14 EGC38872.1 - 3.6 8.1 27.2 1.7 9.2 25.4 1.4 1 1 0 1 1 1 0 Prothymosin/parathymosin family Peptidase_C1 PF00112.23 EGC38873.1 - 7.1e-69 232.2 2.8 1.2e-68 231.5 2.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.12 EGC38873.1 - 5.5e-13 49.1 3.1 8.7e-13 48.5 3.1 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC38873.1 - 1.4e-05 24.1 0.1 0.012 14.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family BetaGal_dom2 PF10435.9 EGC38873.1 - 0.039 13.8 0.2 0.066 13.0 0.2 1.3 1 0 0 1 1 1 0 Beta-galactosidase, domain 2 Ibs_toxin PF13956.6 EGC38873.1 - 0.58 10.2 2.1 1.3 9.1 2.1 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system PI3_PI4_kinase PF00454.27 EGC38875.1 - 1.7e-40 139.4 7.7 6.4e-40 137.5 1.0 3.1 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.20 EGC38875.1 - 5.7e-28 97.6 0.2 1.8e-27 95.9 0.2 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.29 EGC38875.1 - 6.8e-13 49.1 0.1 2.7e-12 47.1 0.1 2.2 1 0 0 1 1 1 1 PH domain PI3K_C2 PF00792.24 EGC38875.1 - 0.00025 21.0 0.3 0.0015 18.5 0.3 2.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF4135 PF13575.6 EGC38875.1 - 0.005 16.2 0.0 0.011 15.1 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Kinesin PF00225.23 EGC38876.1 - 1e-110 369.8 0.1 1e-110 369.8 0.1 3.3 3 0 0 3 3 2 1 Kinesin motor domain Kinesin_assoc PF16183.5 EGC38876.1 - 4.3e-27 95.4 6.0 4.1e-22 79.2 1.4 7.6 5 2 2 8 8 7 2 Kinesin-associated Microtub_bd PF16796.5 EGC38876.1 - 6.9e-20 71.5 0.0 6.9e-20 71.5 0.0 3.4 3 0 0 3 3 3 1 Microtubule binding PH PF00169.29 EGC38876.1 - 1.2e-15 57.9 2.7 8.5e-15 55.2 1.5 2.9 2 0 0 2 2 2 1 PH domain DUF3694 PF12473.8 EGC38876.1 - 3.3e-07 31.1 4.0 0.0018 19.0 0.0 4.8 3 2 0 3 3 3 1 Kinesin protein PH_8 PF15409.6 EGC38876.1 - 0.0008 19.6 0.2 0.003 17.8 0.2 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Golgin_A5 PF09787.9 EGC38876.1 - 0.0036 16.8 19.7 0.0036 16.8 19.7 6.3 4 1 3 7 7 6 1 Golgin subfamily A member 5 Bromo_TP PF07524.13 EGC38876.1 - 0.012 15.6 0.1 0.086 12.9 0.0 2.3 2 0 0 2 2 2 0 Bromodomain associated KIF1B PF12423.8 EGC38876.1 - 0.035 14.5 1.0 0.18 12.3 0.1 2.9 2 0 0 2 2 1 0 Kinesin protein 1B FHA PF00498.26 EGC38876.1 - 0.057 13.8 1.3 1.1 9.6 0.6 3.3 2 1 0 2 2 2 0 FHA domain Gluconate_2-dh3 PF13618.6 EGC38876.1 - 0.35 11.1 2.0 0.89 9.8 0.8 2.4 2 0 0 2 2 1 0 Gluconate 2-dehydrogenase subunit 3 NBD_C PF17042.5 EGC38876.1 - 2.3 8.7 14.2 1.6 9.2 4.8 3.2 2 0 0 2 2 2 0 Nucleotide-binding C-terminal domain FtsX_ECD PF18075.1 EGC38876.1 - 3.1 8.5 30.8 0.021 15.4 6.7 5.5 4 2 1 5 5 4 0 FtsX extracellular domain Epimerase PF01370.21 EGC38877.1 - 2.9e-08 33.5 0.1 0.0012 18.4 0.0 2.1 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.14 EGC38877.1 - 0.00023 20.8 0.6 0.00052 19.6 0.6 1.6 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2-Hacid_dh_C PF02826.19 EGC38877.1 - 0.018 14.4 0.1 0.033 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_2 PF03446.15 EGC38877.1 - 0.02 15.1 0.0 0.033 14.4 0.0 1.3 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase Pyr_redox PF00070.27 EGC38877.1 - 0.061 13.9 0.3 0.22 12.1 0.1 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase TrkA_N PF02254.18 EGC38877.1 - 0.062 13.6 0.1 0.13 12.5 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain GDP_Man_Dehyd PF16363.5 EGC38877.1 - 0.069 12.5 0.2 4 6.7 0.0 2.3 2 1 0 2 2 2 0 GDP-mannose 4,6 dehydratase AlaDh_PNT_C PF01262.21 EGC38877.1 - 0.078 12.3 0.0 0.13 11.5 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain zf-C3HC4_3 PF13920.6 EGC38878.1 - 2.3e-08 33.8 8.1 3.8e-08 33.1 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC38878.1 - 5.2e-08 32.6 9.6 1.5e-07 31.2 9.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC38878.1 - 6.5e-08 32.8 9.8 1.1e-07 32.0 9.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC38878.1 - 3e-07 30.2 8.1 5.2e-07 29.4 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38878.1 - 1.1e-05 25.6 7.9 2.9e-05 24.3 7.9 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38878.1 - 0.0015 18.6 4.5 0.0035 17.3 4.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38878.1 - 0.0017 18.3 9.6 0.0034 17.3 9.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC38878.1 - 0.033 14.0 8.8 0.12 12.3 8.8 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC38878.1 - 0.043 14.0 4.2 0.12 12.5 4.2 1.8 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC38878.1 - 0.072 13.3 9.7 0.27 11.4 9.4 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGC38878.1 - 0.12 12.4 7.0 0.28 11.2 7.0 1.6 1 0 0 1 1 1 0 Double zinc ribbon zf-ANAPC11 PF12861.7 EGC38878.1 - 0.75 9.9 5.7 2.1 8.4 5.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC38878.1 - 1.3 8.9 11.4 11 5.9 11.3 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC38878.1 - 2.7 7.7 8.0 4.5 7.0 8.0 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type TPR_1 PF00515.28 EGC38879.1 - 3.4e-13 48.8 6.8 0.019 14.8 0.2 6.6 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGC38879.1 - 2.8e-11 43.5 0.3 0.016 15.5 0.0 5.1 3 2 3 6 6 6 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC38879.1 - 3.6e-11 42.3 3.6 0.0036 17.3 0.6 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC38879.1 - 8.2e-11 41.2 6.3 0.0039 17.3 0.0 7.2 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_17 PF13431.6 EGC38879.1 - 3.7e-08 33.2 0.8 0.065 13.6 0.0 5.5 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC38879.1 - 1.5e-06 28.6 0.1 0.12 12.9 0.0 3.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.6 EGC38879.1 - 7.9e-06 25.5 2.2 6.8 6.5 0.0 5.8 5 1 1 6 6 6 1 TPR repeat TPR_MalT PF17874.1 EGC38879.1 - 1.6e-05 24.5 0.1 0.0039 16.6 0.0 2.3 2 0 0 2 2 2 2 MalT-like TPR region TPR_6 PF13174.6 EGC38879.1 - 3.4e-05 24.2 0.2 0.011 16.4 0.1 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC38879.1 - 6.9e-05 23.3 0.0 6.1 7.9 0.0 4.9 4 3 3 7 7 5 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC38879.1 - 8e-05 22.7 0.0 0.17 12.1 0.0 2.5 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC38879.1 - 0.0016 18.4 1.5 39 4.6 0.0 5.0 5 0 0 5 5 4 0 Tetratricopeptide repeat MAS20 PF02064.15 EGC38879.1 - 0.0024 17.9 6.7 0.014 15.5 1.8 3.2 2 1 1 3 3 3 1 MAS20 protein import receptor SNAP PF14938.6 EGC38879.1 - 0.021 14.2 4.3 0.036 13.5 1.9 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP zf-CCCH_7 PF18586.1 EGC38879.1 - 0.074 13.4 2.4 0.19 12.1 0.1 2.7 2 0 0 2 2 2 0 Chromatin remodeling factor Mit1 C-terminal Zn finger 1 zinc_ribbon_2 PF13240.6 EGC38880.1 - 0.024 14.4 3.0 0.09 12.5 0.6 2.5 2 0 0 2 2 2 0 zinc-ribbon domain PUL PF08324.11 EGC38881.1 - 1.3e-41 142.6 4.0 2.2e-41 141.9 4.0 1.3 1 0 0 1 1 1 1 PUL domain PFU PF09070.11 EGC38881.1 - 1.5e-36 125.1 2.6 3.6e-36 123.9 2.6 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) WD40 PF00400.32 EGC38881.1 - 3.7e-35 119.4 20.9 2.2e-07 31.4 0.2 7.8 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGC38881.1 - 0.0058 16.7 0.0 0.65 10.1 0.0 3.5 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Ribosomal_S17 PF00366.20 EGC38881.1 - 0.069 13.3 0.5 0.84 9.8 0.2 2.7 3 0 0 3 3 3 0 Ribosomal protein S17 PQQ_3 PF13570.6 EGC38881.1 - 0.099 13.2 0.0 5.3 7.7 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Top6b_C PF18000.1 EGC38881.1 - 0.17 12.0 0.1 0.17 12.0 0.1 2.7 3 1 0 3 3 3 0 Type 2 DNA topoisomerase 6 subunit B C-terminal domain IFT81_CH PF18383.1 EGC38881.1 - 0.23 11.7 2.0 1.1 9.5 1.9 2.1 1 1 0 1 1 1 0 Intraflagellar transport 81 calponin homology domain Menin PF05053.13 EGC38881.1 - 0.85 7.9 8.1 2.5 6.3 3.6 2.1 2 0 0 2 2 2 0 Menin Secretin_N_2 PF07655.13 EGC38881.1 - 2.6 8.6 24.7 2.5 8.7 10.9 2.8 2 0 0 2 2 2 0 Secretin N-terminal domain Coiled PF05710.12 EGC38882.1 - 2.6e-07 31.3 5.8 3e-07 31.1 5.8 1.1 1 0 0 1 1 1 1 Coiled coil Kinesin PF00225.23 EGC38883.1 - 8e-107 357.0 2.5 8e-107 357.0 2.5 1.7 2 0 0 2 2 2 1 Kinesin motor domain Microtub_bd PF16796.5 EGC38883.1 - 1.9e-25 89.5 0.5 1.9e-25 89.5 0.5 2.9 4 0 0 4 4 4 1 Microtubule binding ATG16 PF08614.11 EGC38883.1 - 0.00017 21.9 32.6 0.14 12.4 15.5 3.4 2 1 0 2 2 2 2 Autophagy protein 16 (ATG16) APG6_N PF17675.1 EGC38883.1 - 0.091 13.3 37.3 0.43 11.1 13.1 3.4 2 1 1 3 3 3 0 Apg6 coiled-coil region UPF0242 PF06785.11 EGC38883.1 - 0.81 9.8 29.8 1.3 9.1 7.7 2.4 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus PCRF PF03462.18 EGC38883.1 - 8.7 6.2 25.2 0.43 10.4 8.0 2.3 2 0 0 2 2 2 0 PCRF domain Ank_4 PF13637.6 EGC38884.1 - 2.4e-08 34.4 0.0 0.00071 20.1 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) F-box-like PF12937.7 EGC38884.1 - 8.3e-08 32.0 0.2 2e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.6 EGC38884.1 - 8.9e-07 29.1 0.0 0.087 13.2 0.0 3.3 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC38884.1 - 1.3e-06 28.9 0.0 7e-06 26.5 0.0 2.4 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) F-box PF00646.33 EGC38884.1 - 2.7e-05 23.9 0.4 9.8e-05 22.1 0.4 2.1 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.6 EGC38884.1 - 4.7e-05 23.5 0.0 0.45 11.2 0.0 3.9 3 0 0 3 3 3 2 Ankyrin repeat ShlB PF03865.13 EGC38885.1 - 0.077 12.4 0.6 0.09 12.2 0.6 1.0 1 0 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB AAA_18 PF13238.6 EGC38886.1 - 2.6e-07 31.2 0.4 6.9e-07 29.9 0.2 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EGC38886.1 - 7e-06 26.3 5.0 0.00057 20.1 5.0 2.5 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_17 PF13207.6 EGC38886.1 - 0.00062 20.2 0.1 0.0016 18.9 0.1 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC38886.1 - 0.0013 19.1 0.1 0.0036 17.7 0.1 1.8 1 1 0 1 1 1 1 AAA ATPase domain Cytidylate_kin PF02224.18 EGC38886.1 - 0.004 16.9 1.2 3.1 7.5 0.0 3.1 2 1 1 3 3 3 2 Cytidylate kinase DUF3510 PF12022.8 EGC38886.1 - 0.11 12.9 0.1 0.28 11.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3510) Got1 PF04178.12 EGC38887.1 - 2.7e-30 105.1 20.6 3.4e-30 104.8 20.6 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.6 EGC38887.1 - 3.1 8.0 16.5 6.1 7.0 1.5 2.3 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF2244 PF10003.9 EGC38887.1 - 5.9 6.6 16.0 2 8.1 3.8 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF3792 PF12670.7 EGC38887.1 - 8.5 6.6 22.8 1.8 8.8 10.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) DUF2070 PF09843.9 EGC38887.1 - 9.1 4.4 11.3 11 4.1 11.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2070) DUF3430 PF11912.8 EGC38888.1 - 1.4e-13 51.3 29.8 1.7e-13 51.2 29.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) KH_1 PF00013.29 EGC38889.1 - 3.6e-28 97.2 4.5 4e-16 58.6 0.7 2.9 3 0 0 3 3 3 2 KH domain Ank_2 PF12796.7 EGC38889.1 - 6.1e-12 46.0 0.1 1.9e-11 44.4 0.0 1.9 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC38889.1 - 2.2e-09 37.7 0.0 1.2e-05 25.7 0.0 3.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC38889.1 - 2.9e-09 36.9 0.1 0.0015 18.9 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.6 EGC38889.1 - 1.6e-08 34.6 1.5 2.1e-05 24.7 0.0 2.9 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC38889.1 - 1.2e-07 31.4 0.1 0.041 14.4 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat SLS PF14611.6 EGC38889.1 - 3.9e-07 30.1 3.9 0.0055 16.6 0.4 2.2 1 1 1 2 2 2 2 Mitochondrial inner-membrane-bound regulator KH_4 PF13083.6 EGC38889.1 - 3.8e-06 26.7 0.2 0.12 12.3 0.0 2.9 2 0 0 2 2 2 2 KH domain KH_2 PF07650.17 EGC38889.1 - 8.2e-05 22.4 1.8 0.013 15.3 0.4 2.7 2 0 0 2 2 2 2 KH domain ATP13 PF12921.7 EGC38889.1 - 0.034 14.0 0.8 13 5.6 0.2 3.1 3 0 0 3 3 3 0 Mitochondrial ATPase expression PPR PF01535.20 EGC38889.1 - 0.14 12.4 0.1 34 5.0 0.0 3.2 3 0 0 3 3 3 0 PPR repeat KH_5 PF13184.6 EGC38889.1 - 0.19 11.8 1.7 3.4 7.8 0.2 2.8 2 0 0 2 2 2 0 NusA-like KH domain Fe_hyd_lg_C PF02906.14 EGC38890.1 - 2.8e-74 249.9 0.0 4.8e-74 249.1 0.0 1.4 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.17 EGC38890.1 - 1.7e-10 40.8 0.2 4.1e-10 39.6 0.2 1.6 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.12 EGC38890.1 - 0.0038 17.1 0.2 0.008 16.1 0.2 1.5 1 0 0 1 1 1 1 FAD synthetase Cas_Csd1 PF09709.10 EGC38890.1 - 0.01 14.6 0.0 0.016 13.9 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_Csd1) KaiA PF07688.12 EGC38890.1 - 1 9.5 4.0 51 4.0 0.1 3.6 3 1 0 3 3 3 0 KaiA C-terminal domain Cation_efflux PF01545.21 EGC38891.1 - 5.1e-49 166.7 6.4 5.1e-49 166.7 6.4 3.1 3 1 0 3 3 3 1 Cation efflux family DUF1686 PF07937.11 EGC38891.1 - 0.038 13.9 0.4 0.038 13.9 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) TAP35_44 PF07265.11 EGC38891.1 - 0.32 11.0 2.0 0.9 9.6 0.1 2.5 2 1 0 2 2 2 0 Tapetum specific protein TAP35/TAP44 DAD PF02109.16 EGC38893.1 - 1.1e-40 138.4 5.7 1.2e-40 138.2 5.7 1.0 1 0 0 1 1 1 1 DAD family Diphthamide_syn PF01866.17 EGC38893.1 - 0.18 11.2 1.7 0.29 10.5 1.2 1.5 1 1 1 2 2 2 0 Putative diphthamide synthesis protein DUF2207 PF09972.9 EGC38893.1 - 0.39 9.4 2.6 0.43 9.3 2.6 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) ParA PF10609.9 EGC38894.1 - 1.2e-101 339.3 0.8 1.5e-101 339.0 0.8 1.1 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGC38894.1 - 3.8e-11 43.1 0.0 1.1e-10 41.7 0.0 1.8 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGC38894.1 - 1.3e-07 31.7 2.5 1.4e-07 31.6 0.6 2.2 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.18 EGC38894.1 - 1.3e-05 24.8 0.5 0.024 14.1 0.0 2.4 2 1 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family MipZ PF09140.11 EGC38894.1 - 4.8e-05 22.8 0.1 8.6e-05 21.9 0.1 1.5 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.15 EGC38894.1 - 0.00041 19.6 0.1 0.014 14.6 0.0 2.5 2 1 0 2 2 2 1 Anion-transporting ATPase VirC1 PF07015.11 EGC38894.1 - 0.006 15.9 0.0 0.011 15.1 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein AAA_25 PF13481.6 EGC38894.1 - 0.12 12.0 0.1 0.24 10.9 0.1 1.5 1 0 0 1 1 1 0 AAA domain Vault PF01505.18 EGC38895.1 - 3.9e-60 199.8 0.3 5.2e-16 58.5 0.0 5.6 5 0 0 5 5 5 4 Major Vault Protein repeat domain MVP_shoulder PF11978.8 EGC38895.1 - 2.6e-46 156.5 0.0 5.4e-46 155.5 0.0 1.6 1 0 0 1 1 1 1 Shoulder domain Vault_2 PF17794.1 EGC38895.1 - 2.4e-35 120.7 0.2 8e-21 74.2 0.1 2.7 2 0 0 2 2 2 2 Major Vault Protein repeat domain Vault_3 PF17795.1 EGC38895.1 - 3.8e-35 119.7 1.0 1.9e-30 104.7 0.0 3.3 3 0 0 3 3 3 2 Major Vault Protein Repeat domain Vault_4 PF17796.1 EGC38895.1 - 1.4e-21 76.3 0.1 3.4e-20 71.9 0.0 3.0 3 0 0 3 3 3 1 Major Vault Protein repeat domain Phosphorylase PF00343.20 EGC38896.1 - 0 1054.5 0.1 0 1054.1 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate phosphorylase Nucleoporin_N PF08801.11 EGC38897.1 - 7.7e-48 163.3 8.3 1.4e-47 162.4 8.3 1.4 1 0 0 1 1 1 1 Nup133 N terminal like CRR7 PF12095.8 EGC38897.1 - 2.3 8.7 8.5 5.2 7.6 0.1 4.2 4 0 0 4 4 4 0 Protein CHLORORESPIRATORY REDUCTION 7 Acetyltransf_1 PF00583.25 EGC38898.1 - 8.1e-09 35.7 0.0 1e-08 35.4 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC38898.1 - 7.8e-08 32.6 0.1 1.2e-07 32.0 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC38898.1 - 2.8e-05 24.0 0.0 4.8e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.7 EGC38898.1 - 0.00035 20.7 0.0 0.007 16.4 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC38898.1 - 0.0042 17.2 0.0 0.0076 16.4 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.10 EGC38898.1 - 0.0047 16.9 0.0 0.0081 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Nipped-B_C PF12830.7 EGC38898.1 - 0.0098 15.8 0.0 0.021 14.8 0.0 1.4 2 0 0 2 2 2 1 Sister chromatid cohesion C-terminus GNAT_acetyltran PF12746.7 EGC38898.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_15 PF17013.5 EGC38898.1 - 0.11 11.9 3.4 0.093 12.2 1.4 1.7 1 1 0 1 1 1 0 Putative acetyl-transferase DUF3430 PF11912.8 EGC38899.1 - 4.9e-11 43.1 30.2 6.4e-11 42.7 30.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.8 EGC38899.1 - 1.8 8.8 9.5 3.4 7.9 0.4 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) zf-B_box PF00643.24 EGC38901.1 - 0.00041 20.4 9.2 0.00093 19.3 9.2 1.6 1 0 0 1 1 1 1 B-box zinc finger Rx_N PF18052.1 EGC38901.1 - 0.0073 16.6 0.9 2.1 8.7 0.1 2.3 2 0 0 2 2 2 2 Rx N-terminal domain Atypical_Card PF18461.1 EGC38901.1 - 0.014 15.6 0.6 0.046 13.9 0.6 2.0 1 0 0 1 1 1 0 Atypical caspase recruitment domain Exonuc_VII_L PF02601.15 EGC38901.1 - 0.021 14.4 2.5 0.028 14.0 2.5 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RecO_N_2 PF13114.6 EGC38901.1 - 0.035 13.8 0.0 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 RecO N terminal YlbD_coat PF14071.6 EGC38901.1 - 0.038 14.2 14.5 0.031 14.5 12.0 2.1 1 1 1 2 2 2 0 Putative coat protein ECH_2 PF16113.5 EGC38901.1 - 0.044 13.3 0.8 0.058 12.9 0.8 1.1 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase DUF1539 PF07560.11 EGC38901.1 - 0.047 13.8 9.7 0.14 12.2 9.7 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) V-SNARE PF05008.15 EGC38901.1 - 0.062 13.7 6.4 0.61 10.5 0.4 2.7 2 1 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus Med30 PF11315.8 EGC38901.1 - 0.15 12.3 9.5 0.28 11.4 9.5 1.4 1 0 0 1 1 1 0 Mediator complex subunit 30 Fer4_20 PF14691.6 EGC38901.1 - 0.31 10.8 4.6 0.52 10.1 1.7 2.3 1 1 1 2 2 2 0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster FlaC_arch PF05377.11 EGC38901.1 - 0.46 10.9 12.2 1.1 9.7 0.8 3.7 2 1 0 3 3 3 0 Flagella accessory protein C (FlaC) TMPIT PF07851.13 EGC38901.1 - 0.48 9.6 8.6 0.76 9.0 8.6 1.4 1 0 0 1 1 1 0 TMPIT-like protein Peptidase_C71 PF12386.8 EGC38902.1 - 1.6e-05 24.6 4.1 0.00046 19.9 0.1 2.7 2 0 0 2 2 2 2 Pseudomurein endo-isopeptidase Pei DUF3430 PF11912.8 EGC38903.1 - 1e-17 64.9 16.7 1.1e-17 64.8 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Peptidase_M16_C PF05193.21 EGC38904.1 - 1e-22 81.0 0.1 4.6e-22 78.9 0.0 1.9 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.20 EGC38904.1 - 2.7e-15 56.6 0.1 9.4e-15 54.9 0.0 1.9 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) AAA_12 PF13087.6 EGC38905.1 - 7.5e-27 94.2 0.0 5.9e-26 91.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGC38905.1 - 9.3e-08 32.2 0.3 3.4e-05 23.8 0.0 5.5 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.6 EGC38905.1 - 0.018 14.8 0.0 0.044 13.5 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SSE PF00437.20 EGC38905.1 - 0.061 12.4 0.1 0.13 11.3 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EGC38905.1 - 0.091 12.3 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Viral_helicase1 PF01443.18 EGC38905.1 - 0.12 12.1 0.0 1.5 8.5 0.0 2.6 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_30 PF13604.6 EGC38905.1 - 0.21 11.3 0.0 0.38 10.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain RhoGEF PF00621.20 EGC38908.1 - 2.5e-44 151.7 10.8 2.5e-44 151.7 10.8 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC38908.1 - 3.3e-14 53.3 5.0 5.1e-14 52.7 0.3 3.5 3 1 0 3 3 3 1 PH domain PH_3 PF14593.6 EGC38908.1 - 2.1e-08 34.2 2.1 3.4e-08 33.5 0.5 2.2 2 0 0 2 2 2 1 PH domain PH_8 PF15409.6 EGC38908.1 - 2.4e-05 24.5 0.4 8.5e-05 22.8 0.4 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain DNApol3-delta_C PF09115.10 EGC38908.1 - 0.018 15.5 0.0 0.07 13.6 0.0 2.1 1 0 0 1 1 1 0 DNA polymerase III, delta subunit, C terminal PH_11 PF15413.6 EGC38908.1 - 0.024 15.1 1.3 0.024 15.1 1.3 4.0 4 1 1 5 5 5 0 Pleckstrin homology domain FeoB_Cyto PF17910.1 EGC38908.1 - 1.4 9.5 4.8 1.4 9.5 1.8 2.6 2 0 0 2 2 2 0 FeoB cytosolic helical domain LSM PF01423.22 EGC38909.1 - 8.3e-10 38.2 0.6 1.4e-09 37.5 0.6 1.4 1 0 0 1 1 1 1 LSM domain Tox-MPTase3 PF15639.6 EGC38909.1 - 0.036 13.9 0.1 0.058 13.3 0.0 1.3 1 1 0 1 1 1 0 Metallopeptidase toxin 3 DUF1256 PF06866.11 EGC38909.1 - 0.096 12.1 0.1 0.12 11.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) UPF0552 PF10574.9 EGC38910.1 - 1.5e-26 93.2 0.1 1.7e-26 92.9 0.1 1.1 1 0 0 1 1 1 1 Arp2/3-interacting proteins Arpin IBN_N PF03810.19 EGC38910.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.7 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF1308 PF07000.11 EGC38910.1 - 0.092 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1308) GP52 PF17468.2 EGC38910.1 - 0.15 12.2 0.0 0.28 11.4 0.0 1.4 1 0 0 1 1 1 0 Phage gene product 52 RE_XamI PF09572.10 EGC38911.1 - 0.03 14.0 1.3 0.047 13.4 1.3 1.3 1 0 0 1 1 1 0 XamI restriction endonuclease RNA_pol_Rpb2_4 PF04566.13 EGC38911.1 - 0.18 12.1 0.7 0.37 11.1 0.7 1.5 1 0 0 1 1 1 0 RNA polymerase Rpb2, domain 4 CBM_25 PF03423.13 EGC38911.1 - 1.2 9.4 5.6 1 9.7 1.9 2.4 2 0 0 2 2 2 0 Carbohydrate binding domain (family 25) F-box PF00646.33 EGC38912.1 - 3.7e-08 33.1 2.6 1.2e-07 31.4 0.2 3.1 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGC38912.1 - 4.9e-08 32.7 0.1 1.6e-07 31.1 0.1 1.9 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.6 EGC38912.1 - 0.057 13.2 0.4 0.057 13.2 0.4 5.8 5 1 1 6 6 6 0 Leucine rich repeat Vac7 PF12751.7 EGC38912.1 - 1.8 7.9 9.2 3.3 7.1 9.2 1.3 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 EF-hand_6 PF13405.6 EGC38913.1 - 1.9e-11 42.9 14.3 0.0012 18.6 0.2 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.32 EGC38913.1 - 4.1e-11 41.6 14.0 0.0016 17.9 0.5 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC38913.1 - 9.2e-10 38.8 13.9 4.6e-06 27.0 4.8 3.1 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.6 EGC38913.1 - 1.1e-07 31.5 5.0 0.00016 21.4 0.2 3.3 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.6 EGC38913.1 - 4.3e-06 26.0 8.7 0.00051 19.4 0.1 3.7 3 0 0 3 3 3 2 EF hand DUF5003 PF16394.5 EGC38913.1 - 0.023 13.9 1.0 0.024 13.8 1.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5003) Syntaphilin PF15290.6 EGC38913.1 - 0.025 14.3 0.4 0.03 14.0 0.4 1.1 1 0 0 1 1 1 0 Golgi-localised syntaxin-1-binding clamp Caleosin PF05042.13 EGC38913.1 - 0.17 11.8 2.8 2.6 8.0 0.3 2.8 2 2 0 2 2 2 0 Caleosin related protein PseudoU_synth_1 PF01416.20 EGC38915.1 - 3.8e-13 49.8 0.0 7.2e-09 36.1 0.0 2.6 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.9 EGC38915.1 - 0.015 15.1 0.0 0.033 14.0 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) YhhN PF07947.14 EGC38916.1 - 2.9e-07 30.3 6.7 0.00011 21.8 0.5 2.6 3 0 0 3 3 3 2 YhhN family COesterase PF00135.28 EGC38917.1 - 5e-115 385.3 0.0 6.7e-115 384.9 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC38917.1 - 0.0043 16.9 0.0 0.0088 15.9 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC38917.1 - 0.084 12.3 0.0 0.13 11.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family Caskin-tail PF16632.5 EGC38918.1 - 6.3 7.3 13.3 3.9 8.0 4.1 2.6 2 0 0 2 2 2 0 C-terminal region of Caskin Helo_like_N PF17111.5 EGC38918.1 - 9.9 5.5 14.5 2.6 7.4 4.5 2.3 1 1 1 2 2 2 0 Fungal N-terminal domain of STAND proteins RNA_pol_Rpb6 PF01192.22 EGC38919.1 - 2.4e-14 53.0 0.1 3.9e-14 52.3 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase Rpb6 GAGA_bind PF06217.12 EGC38920.1 - 0.025 14.9 3.9 0.03 14.6 3.9 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Spt20 PF12090.8 EGC38920.1 - 0.062 12.9 17.4 0.084 12.5 17.4 1.2 1 0 0 1 1 1 0 Spt20 family V_ATPase_I PF01496.19 EGC38920.1 - 0.072 11.0 10.0 0.087 10.7 10.0 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CLN3 PF02487.17 EGC38920.1 - 0.25 10.4 11.2 0.28 10.2 11.2 1.2 1 1 0 1 1 1 0 CLN3 protein MAP17 PF15807.5 EGC38920.1 - 0.34 11.2 6.4 0.49 10.6 6.4 1.3 1 0 0 1 1 1 0 Membrane-associated protein 117 kDa, PDZK1-interacting protein 1 TERB2 PF15101.6 EGC38920.1 - 0.49 10.4 9.4 0.59 10.2 9.4 1.2 1 0 0 1 1 1 0 Telomere-associated protein TERB2 Peptidase_S49_N PF08496.10 EGC38920.1 - 1.1 9.3 7.8 1.5 8.9 7.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Zip PF02535.22 EGC38920.1 - 3.7 6.7 5.3 4.5 6.4 5.3 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Connexin PF00029.19 EGC38920.1 - 5.9 6.6 11.0 8.1 6.1 11.0 1.3 1 1 0 1 1 1 0 Connexin SelR PF01641.18 EGC38922.1 - 8.1e-50 167.9 0.0 9.2e-50 167.8 0.0 1.0 1 0 0 1 1 1 1 SelR domain Yippee-Mis18 PF03226.14 EGC38922.1 - 0.017 15.3 0.6 0.038 14.2 0.6 1.6 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGC38922.1 - 0.11 12.8 0.1 0.28 11.4 0.1 1.7 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-Mss51 PF13824.6 EGC38922.1 - 0.34 11.0 0.2 0.34 11.0 0.2 2.6 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Ribosomal_L37e PF01907.19 EGC38922.1 - 0.49 10.6 4.7 1.8 8.8 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e FUSC_2 PF13515.6 EGC38923.1 - 2.6e-14 53.4 13.2 2.6e-14 53.4 13.2 2.5 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.8 EGC38923.1 - 3.9e-13 49.1 6.8 3.9e-13 49.1 6.8 2.7 3 0 0 3 3 3 1 Aluminium activated malate transporter FUSC PF04632.12 EGC38923.1 - 0.14 10.7 5.1 0.23 10.0 5.1 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family Syntaxin-6_N PF09177.11 EGC38923.1 - 0.64 10.6 4.9 1.2 9.7 2.5 2.7 2 1 0 2 2 2 0 Syntaxin 6, N-terminal BTB PF00651.31 EGC38924.1 - 8.7e-14 51.7 1.6 3.1e-12 46.7 1.6 2.7 1 1 0 1 1 1 1 BTB/POZ domain BACK PF07707.15 EGC38924.1 - 1.7e-10 40.9 0.9 2.4e-07 30.8 0.1 2.6 2 0 0 2 2 2 2 BTB And C-terminal Kelch Vfa1 PF08432.10 EGC38924.1 - 0.012 15.9 6.1 0.012 15.9 6.1 2.5 3 0 0 3 3 3 0 AAA-ATPase Vps4-associated protein 1 DUF4702 PF15774.5 EGC38924.1 - 0.047 12.6 0.1 0.047 12.6 0.1 3.5 5 0 0 5 5 5 0 Domain of unknown function (DUF4702) CENP-B_dimeris PF09026.10 EGC38924.1 - 0.27 11.7 6.8 0.049 14.0 1.6 2.3 2 0 0 2 2 2 0 Centromere protein B dimerisation domain CobT PF06213.12 EGC38924.1 - 0.8 9.0 8.1 1.4 8.2 8.1 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT FAM176 PF14851.6 EGC38924.1 - 0.94 9.1 8.7 1.1 8.9 5.2 2.5 2 0 0 2 2 2 0 FAM176 family Connexin PF00029.19 EGC38924.1 - 1.8 8.2 4.4 0.62 9.8 1.0 1.9 2 0 0 2 2 2 0 Connexin Ferlin_C PF16165.5 EGC38924.1 - 5 7.0 7.5 14 5.6 7.5 1.7 1 0 0 1 1 1 0 Ferlin C-terminus GATA PF00320.27 EGC38925.1 - 1e-16 60.2 5.8 2.7e-16 58.9 5.8 1.8 1 0 0 1 1 1 1 GATA zinc finger DUF4014 PF13198.6 EGC38925.1 - 0.001 19.4 0.0 0.002 18.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4014) zf-C2H2_3 PF13878.6 EGC38925.1 - 0.12 12.2 0.2 0.76 9.7 0.0 2.2 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO DZR PF12773.7 EGC38925.1 - 0.12 12.4 0.8 0.28 11.2 0.8 1.6 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.6 EGC38925.1 - 0.61 9.9 2.5 0.94 9.3 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain ATP-synt_ab PF00006.25 EGC38926.1 - 5.6e-62 209.2 0.0 9.1e-62 208.5 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_N PF02874.23 EGC38926.1 - 2.7e-16 59.9 0.9 5.5e-15 55.6 0.9 2.6 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain RsgA_GTPase PF03193.16 EGC38926.1 - 0.0026 17.7 0.1 0.0072 16.3 0.1 1.7 1 0 0 1 1 1 1 RsgA GTPase NB-ARC PF00931.22 EGC38926.1 - 0.0031 16.8 0.7 0.0082 15.3 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_16 PF13191.6 EGC38926.1 - 0.044 14.2 0.8 0.12 12.8 0.1 2.1 3 0 0 3 3 2 0 AAA ATPase domain NACHT PF05729.12 EGC38926.1 - 0.047 13.6 0.1 0.13 12.1 0.1 1.7 1 0 0 1 1 1 0 NACHT domain RNA_helicase PF00910.22 EGC38926.1 - 0.052 13.9 0.0 0.46 10.9 0.0 2.5 3 0 0 3 3 3 0 RNA helicase ATPase PF06745.13 EGC38926.1 - 0.057 12.8 0.5 0.17 11.2 0.5 1.8 1 0 0 1 1 1 0 KaiC YflT PF11181.8 EGC38926.1 - 0.08 13.5 1.1 0.25 11.8 1.1 1.9 1 0 0 1 1 1 0 Heat induced stress protein YflT AAA_22 PF13401.6 EGC38926.1 - 0.099 12.9 0.1 0.6 10.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.29 EGC38926.1 - 0.11 12.9 0.1 1.1 9.7 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.6 EGC38926.1 - 0.15 12.4 1.0 0.44 10.9 0.1 2.1 2 1 0 2 2 2 0 AAA domain Acyltransferase PF01553.21 EGC38927.1 - 1.5e-20 73.2 0.0 2.4e-20 72.5 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Acyltransf_C PF16076.5 EGC38927.1 - 1.5e-17 63.4 0.1 3.1e-17 62.4 0.1 1.6 1 0 0 1 1 1 1 Acyltransferase C-terminus Nup54 PF13874.6 EGC38928.1 - 7.5e-36 123.3 5.7 7.5e-36 123.3 5.7 2.5 3 0 0 3 3 3 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.6 EGC38928.1 - 2.4e-13 50.7 69.3 2e-10 41.4 31.8 3.0 1 1 0 2 2 2 2 Nucleoporin FG repeat region Collagen PF01391.18 EGC38928.1 - 0.44 10.4 7.3 0.089 12.6 2.3 2.1 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) Suf PF05843.14 EGC38928.1 - 4.1 7.3 19.1 0.29 11.1 8.4 2.3 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) DUF4407 PF14362.6 EGC38928.1 - 9.8 5.4 15.5 6.2 6.1 2.2 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) COX6B PF02297.17 EGC38929.1 - 4.5e-18 65.3 8.1 4.5e-18 65.3 8.1 1.5 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb YnfE PF17452.2 EGC38929.1 - 0.0023 18.2 1.4 0.015 15.6 1.2 2.1 1 1 0 1 1 1 1 Uncharacterized YnfE-like CHCH PF06747.13 EGC38929.1 - 0.0024 18.0 9.6 0.0063 16.6 8.7 2.3 1 1 1 2 2 2 1 CHCH domain DUF5512 PF17631.2 EGC38929.1 - 0.008 16.2 2.7 0.012 15.7 1.2 1.8 1 1 1 2 2 2 1 Family of unknown function (DUF5512) MTCP1 PF08991.10 EGC38929.1 - 0.08 13.2 3.4 0.14 12.4 3.4 1.4 1 0 0 1 1 1 0 Mature-T-Cell Proliferation I type Orn_Arg_deC_N PF02784.16 EGC38930.1 - 3e-32 111.9 0.0 4e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.22 EGC38930.1 - 1.2e-18 67.1 0.0 2.3e-18 66.2 0.0 1.4 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IBN_N PF03810.19 EGC38931.1 - 1.6e-15 56.7 0.5 4.7e-13 48.9 0.1 3.7 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.10 EGC38931.1 - 3.2e-07 29.5 5.2 6.1e-07 28.6 0.1 3.6 3 1 1 4 4 4 1 Cse1 Xpo1 PF08389.12 EGC38931.1 - 0.0011 19.0 2.2 0.0011 19.0 2.2 3.8 4 1 0 4 4 4 1 Exportin 1-like protein Vac14_Fab1_bd PF12755.7 EGC38931.1 - 0.0092 16.6 0.9 1.3 9.6 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region ELO PF01151.18 EGC38932.1 - 6.8e-51 173.2 21.3 9.2e-49 166.2 21.3 2.0 1 1 0 1 1 1 1 GNS1/SUR4 family Tetraspanin PF00335.20 EGC38933.1 - 2.3e-31 109.3 8.7 2.7e-31 109.1 8.7 1.0 1 0 0 1 1 1 1 Tetraspanin family G0-G1_switch_2 PF15103.6 EGC38933.1 - 0.001 19.5 0.3 1.7 9.1 0.0 2.3 2 0 0 2 2 2 2 G0/G1 switch protein 2 DUF373 PF04123.13 EGC38933.1 - 0.01 15.3 3.5 0.018 14.5 3.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2976 PF11190.8 EGC38933.1 - 0.021 14.6 1.9 0.021 14.6 1.9 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) UL41A PF17591.2 EGC38933.1 - 0.084 13.0 8.5 0.59 10.3 0.4 2.9 3 0 0 3 3 3 0 Herpesvirus UL41A CcmH PF03918.14 EGC38933.1 - 0.76 9.1 2.1 0.96 8.7 0.1 2.1 1 1 1 2 2 2 0 Cytochrome C biogenesis protein STE3 PF02076.15 EGC38933.1 - 3.6 6.7 8.8 0.24 10.6 1.9 2.3 2 1 1 3 3 3 0 Pheromone A receptor Med27 PF11571.8 EGC38934.1 - 1.7e-20 73.2 0.1 1.7e-20 73.2 0.1 3.5 2 1 0 2 2 2 1 Mediator complex subunit 27 Prok-RING_1 PF14446.6 EGC38934.1 - 0.23 11.4 1.5 0.4 10.6 0.2 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Caldesmon PF02029.15 EGC38934.1 - 2.9 6.6 31.1 3.9 6.1 31.1 1.3 1 0 0 1 1 1 0 Caldesmon zf-CHY PF05495.12 EGC38935.1 - 3.1e-12 46.8 18.8 5.9e-12 45.9 18.8 1.4 1 0 0 1 1 1 1 CHY zinc finger zinc_ribbon_9 PF14369.6 EGC38935.1 - 0.00051 20.2 6.3 0.097 13.0 2.0 2.5 2 0 0 2 2 2 2 zinc-ribbon Zn-ribbon_8 PF09723.10 EGC38935.1 - 0.0018 18.3 4.3 0.0018 18.3 4.3 2.6 2 1 1 3 3 3 1 Zinc ribbon domain Plasmo_rep PF12135.8 EGC38935.1 - 0.14 11.8 0.8 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 Plasmodium repeat family zf-C2H2_6 PF13912.6 EGC38935.1 - 0.3 11.2 8.2 0.65 10.1 2.3 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger RNA_POL_M_15KD PF02150.16 EGC38935.1 - 0.93 9.4 9.5 5.3 7.0 0.1 3.2 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit zf-C2H2 PF00096.26 EGC38935.1 - 3.2 8.4 13.7 2.4 8.8 0.9 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type NOB1_Zn_bind PF08772.11 EGC38935.1 - 5 7.4 10.5 0.54 10.5 3.8 2.4 1 1 1 2 2 2 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.7 EGC38935.1 - 5.4 7.1 13.4 12 6.0 0.1 2.8 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Sgf11 PF08209.11 EGC38935.1 - 9.4 5.9 10.8 0.74 9.4 0.5 2.9 3 0 0 3 3 3 0 Sgf11 (transcriptional regulation protein) Epimerase PF01370.21 EGC38936.1 - 4.1e-57 193.4 0.0 5.4e-57 193.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC38936.1 - 3.6e-18 66.0 0.0 5.5e-18 65.5 0.0 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Polysacc_synt_2 PF02719.15 EGC38936.1 - 1.6e-05 24.2 1.1 0.0001 21.5 0.0 2.4 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.17 EGC38936.1 - 0.00011 21.4 0.0 0.00023 20.4 0.0 1.5 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.12 EGC38936.1 - 0.021 14.0 0.1 0.068 12.3 0.0 1.7 1 1 1 2 2 2 0 Male sterility protein DOT1 PF08123.13 EGC38937.1 - 0.00011 21.8 0.8 0.00042 19.9 0.8 1.8 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_3 PF01596.17 EGC38937.1 - 0.00056 19.1 0.9 0.00056 19.1 0.9 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.12 EGC38937.1 - 0.0011 19.7 0.2 0.0051 17.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC38937.1 - 0.0015 19.2 0.0 0.008 16.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.18 EGC38937.1 - 0.0035 16.8 0.8 0.0075 15.8 0.6 1.5 1 1 0 1 1 1 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.12 EGC38937.1 - 0.0035 17.9 0.0 0.0076 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CpXC PF14353.6 EGC38937.1 - 0.027 14.5 0.0 0.12 12.4 0.0 2.0 2 0 0 2 2 2 0 CpXC protein Methyltransf_9 PF08003.11 EGC38937.1 - 0.071 12.0 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) TelA PF05816.11 EGC38937.1 - 0.9 8.5 3.5 11 5.0 0.1 2.1 2 0 0 2 2 2 0 Toxic anion resistance protein (TelA) DUF1624 PF07786.12 EGC38938.1 - 2.9e-07 30.3 11.2 2.9e-07 30.3 11.2 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) DUF5009 PF16401.5 EGC38938.1 - 0.00012 21.7 5.3 0.00012 21.7 5.3 3.4 3 1 0 4 4 4 2 Domain of unknown function (DUF5009) DUF1725 PF08333.11 EGC38938.1 - 0.073 12.7 0.5 0.15 11.8 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1725) Microcin PF03526.13 EGC38939.1 - 0.025 14.4 2.7 0.17 11.7 0.8 2.2 1 1 1 2 2 2 0 Colicin E1 (microcin) immunity protein Foie-gras_1 PF11817.8 EGC38939.1 - 0.089 12.4 0.5 0.094 12.3 0.5 1.1 1 0 0 1 1 1 0 Foie gras liver health family 1 DUF866 PF05907.13 EGC38940.1 - 3.3e-31 108.3 3.2 3.7e-31 108.1 3.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_S27e PF01667.17 EGC38940.1 - 0.055 13.2 3.1 1 9.2 0.5 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 T4_baseplate PF12322.8 EGC38940.1 - 0.11 12.0 3.4 1.5 8.3 0.4 2.2 1 1 1 2 2 2 0 T4 bacteriophage base plate protein TF_Zn_Ribbon PF08271.12 EGC38940.1 - 0.23 11.0 4.6 4 7.0 0.3 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding zf-AN1 PF01428.16 EGC38940.1 - 0.44 10.8 5.6 4 7.7 0.7 2.5 3 0 0 3 3 3 0 AN1-like Zinc finger Cyt-b5 PF00173.28 EGC38941.1 - 1.1e-17 63.9 0.1 3.1e-17 62.5 0.0 1.7 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain DUF5629 PF18629.1 EGC38941.1 - 0.17 12.4 0.0 20 5.8 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF5629) NIF PF03031.18 EGC38942.1 - 2.5e-19 69.6 0.3 4.7e-19 68.7 0.3 1.4 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Adaptin_binding PF10199.9 EGC38942.1 - 0.0014 19.2 1.3 0.0029 18.2 1.3 1.4 1 0 0 1 1 1 1 Alpha and gamma adaptin binding protein p34 DUF2370 PF10176.9 EGC38942.1 - 0.014 15.1 0.5 0.045 13.4 0.1 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2370) EIIBC-GUT_N PF03612.14 EGC38942.1 - 0.043 13.6 2.5 0.075 12.8 2.5 1.3 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus CDC45 PF02724.14 EGC38942.1 - 0.14 10.5 3.0 0.2 9.9 3.0 1.2 1 0 0 1 1 1 0 CDC45-like protein Presenilin PF01080.17 EGC38942.1 - 0.37 9.5 1.3 0.49 9.1 1.3 1.1 1 0 0 1 1 1 0 Presenilin DUF3464 PF11947.8 EGC38942.1 - 0.58 9.9 2.3 0.94 9.2 2.3 1.3 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 Tim54 PF11711.8 EGC38942.1 - 0.83 8.4 7.8 1.2 7.8 7.8 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Connexin PF00029.19 EGC38942.1 - 0.87 9.3 3.4 1.3 8.7 3.4 1.3 1 0 0 1 1 1 0 Connexin RNA_pol_Rpc4 PF05132.14 EGC38942.1 - 3.1 8.2 7.3 5.5 7.4 7.3 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 Sec62 PF03839.16 EGC38942.1 - 4.5 6.7 9.7 6.8 6.1 9.7 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 tRNA_bind_2 PF13725.6 EGC38942.1 - 8.7 6.0 11.2 16 5.1 11.2 1.4 1 0 0 1 1 1 0 Possible tRNA binding domain BRAP2 PF07576.12 EGC38943.1 - 5.9e-33 113.0 0.2 1.7e-32 111.6 0.2 1.9 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.19 EGC38943.1 - 1.3e-19 70.3 4.9 1.3e-19 70.3 4.9 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.6 EGC38943.1 - 3.3e-09 36.9 9.5 3.3e-09 36.9 9.5 2.3 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC38943.1 - 1.6e-07 31.1 8.9 6e-07 29.2 8.9 2.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC38943.1 - 6.8e-06 26.3 6.5 6.8e-06 26.3 6.5 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC38943.1 - 3.4e-05 23.8 4.8 0.00014 21.8 4.9 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC38943.1 - 9.5e-05 22.3 7.3 9.5e-05 22.3 7.3 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGC38943.1 - 0.00028 20.7 7.4 0.00028 20.7 7.4 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_11 PF17123.5 EGC38943.1 - 0.00046 19.9 5.6 0.0019 17.9 5.6 2.2 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_3 PF13920.6 EGC38943.1 - 0.0012 18.7 6.5 0.0012 18.7 6.5 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-UBP_var PF17807.1 EGC38943.1 - 0.002 17.9 0.5 0.006 16.3 0.5 1.8 1 0 0 1 1 1 1 Variant UBP zinc finger zf-ANAPC11 PF12861.7 EGC38943.1 - 0.016 15.2 7.0 0.016 15.2 7.0 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.6 EGC38943.1 - 0.026 14.3 5.9 0.067 13.0 5.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain PHF5 PF03660.14 EGC38943.1 - 0.1 12.8 8.5 0.28 11.4 8.5 1.8 1 0 0 1 1 1 0 PHF5-like protein V-ATPase_G_2 PF16999.5 EGC38943.1 - 1.3 9.5 7.0 1 9.8 1.8 2.2 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit Kelch_1 PF01344.25 EGC38944.1 - 8.3e-40 134.1 0.9 1.7e-07 30.7 0.0 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.6 EGC38944.1 - 9.2e-38 128.0 2.2 9.3e-09 35.2 0.0 6.3 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC38944.1 - 1.6e-35 120.7 0.8 1.9e-11 43.9 0.0 6.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.6 EGC38944.1 - 2.9e-34 116.2 6.2 6e-05 23.2 0.1 6.8 6 1 1 7 7 7 6 Kelch motif Kelch_5 PF13854.6 EGC38944.1 - 7.9e-34 115.1 0.1 1.1e-06 28.5 0.0 6.4 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.15 EGC38944.1 - 2.9e-33 112.6 8.9 8.8e-07 28.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif FRG1 PF06229.12 EGC38944.1 - 0.16 11.7 0.0 0.65 9.7 0.0 1.8 2 0 0 2 2 2 0 FRG1-like domain Macoilin PF09726.9 EGC38944.1 - 0.54 8.7 3.6 0.74 8.3 3.6 1.1 1 0 0 1 1 1 0 Macoilin family AAA_18 PF13238.6 EGC38945.1 - 1.7e-16 60.9 0.0 2.6e-16 60.4 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC38945.1 - 6.9e-08 32.9 0.0 1.1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 AAA domain dNK PF01712.19 EGC38945.1 - 8e-08 32.4 2.6 1.6e-07 31.4 2.5 1.6 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_33 PF13671.6 EGC38945.1 - 4.6e-07 30.1 0.0 2e-05 24.8 0.1 2.3 1 1 1 2 2 2 2 AAA domain Thymidylate_kin PF02223.17 EGC38945.1 - 6.7e-06 25.9 0.4 0.0012 18.6 0.4 2.2 2 0 0 2 2 2 2 Thymidylate kinase AAA_17 PF13207.6 EGC38945.1 - 0.0043 17.5 0.3 1.4 9.3 0.1 2.3 2 0 0 2 2 2 2 AAA domain AAA_22 PF13401.6 EGC38945.1 - 0.0063 16.8 0.1 0.025 14.8 0.1 2.0 1 1 1 2 2 2 1 AAA domain TsaE PF02367.17 EGC38945.1 - 0.031 14.3 0.1 0.052 13.6 0.1 1.5 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE SKI PF01202.22 EGC38945.1 - 0.034 14.3 0.7 0.14 12.2 0.3 2.0 2 0 0 2 2 2 0 Shikimate kinase CoaE PF01121.20 EGC38945.1 - 0.33 10.6 2.6 0.46 10.1 0.0 2.3 3 0 0 3 3 3 0 Dephospho-CoA kinase SOXp PF12336.8 EGC38945.1 - 0.45 11.6 2.6 0.42 11.7 0.6 1.9 1 1 1 2 2 2 0 SOX transcription factor Bromodomain PF00439.25 EGC38946.1 - 6.3e-19 67.8 0.1 2.8e-18 65.8 0.0 2.2 2 0 0 2 2 2 1 Bromodomain BET PF17035.5 EGC38946.1 - 7.2e-18 64.5 1.8 7.2e-18 64.5 1.8 4.0 3 0 0 3 3 3 1 Bromodomain extra-terminal - transcription regulation Pribosyltran PF00156.27 EGC38947.1 - 4.7e-12 45.7 0.0 5.5e-11 42.2 0.0 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.6 EGC38947.1 - 0.00087 18.8 0.0 0.0012 18.3 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RRM_1 PF00076.22 EGC38948.1 - 0.0017 18.1 0.0 0.0045 16.8 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Hamartin PF04388.12 EGC38948.1 - 0.099 11.3 22.9 0.12 11.1 22.9 1.1 1 0 0 1 1 1 0 Hamartin protein GREB1 PF15782.5 EGC38948.1 - 0.32 8.1 19.1 0.4 7.8 19.1 1.1 1 0 0 1 1 1 0 Gene regulated by oestrogen in breast cancer DUF2151 PF10221.9 EGC38949.1 - 3e-42 145.2 24.9 3.5e-32 111.9 8.9 3.0 1 1 0 2 2 2 2 Cell cycle and development regulator Trypan_PARP PF05887.11 EGC38950.1 - 1.8 8.6 26.5 5.1 7.1 9.9 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLDc_2 PF13091.6 EGC38951.1 - 4e-26 91.5 0.2 9.3e-17 61.2 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGC38951.1 - 0.00016 21.7 3.8 0.0017 18.4 0.1 2.9 3 0 0 3 3 3 2 Phospholipase D Active site motif SUI1 PF01253.22 EGC38952.1 - 9.9e-20 70.9 1.0 2.2e-19 69.7 1.0 1.6 1 0 0 1 1 1 1 Translation initiation factor SUI1 HNF-1_N PF04814.13 EGC38952.1 - 0.046 14.3 3.6 0.062 13.9 3.6 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus CfAFP PF05264.11 EGC38952.1 - 0.056 13.4 0.1 0.056 13.4 0.1 2.4 2 1 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) MFMR_assoc PF16596.5 EGC38952.1 - 0.76 10.2 10.5 1.1 9.7 10.5 1.2 1 0 0 1 1 1 0 Disordered region downstream of MFMR GET2 PF08690.10 EGC38952.1 - 8.6 5.9 9.1 11 5.6 9.1 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 FNIP PF05725.12 EGC38953.1 - 2.2e-21 75.7 57.8 1.7e-11 44.1 1.1 10.8 9 2 4 13 13 13 10 FNIP Repeat Aldedh PF00171.22 EGC38954.1 - 2.1e-74 250.7 0.0 2.5e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family NYD-SP28 PF14772.6 EGC38954.1 - 0.023 14.8 2.6 0.04 14.0 2.6 1.5 1 0 0 1 1 1 0 Sperm tail Cytochrom_B562 PF07361.11 EGC38954.1 - 0.084 13.5 0.5 0.15 12.7 0.5 1.4 1 0 0 1 1 1 0 Cytochrome b562 Defb50 PF17546.2 EGC38954.1 - 0.11 12.5 0.1 0.89 9.5 0.0 2.3 2 0 0 2 2 2 0 Beta defensin 50 ORC3_N PF07034.11 EGC38955.1 - 1.4e-28 100.0 2.3 1.4e-28 100.0 2.3 2.0 2 0 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus ORC_WH_C PF18137.1 EGC38955.1 - 9.1e-13 48.5 0.8 2.1e-07 31.1 0.2 5.6 4 2 1 5 5 5 2 Origin recognition complex winged helix C-terminal PHD PF00628.29 EGC38955.1 - 0.0076 16.1 8.1 0.0076 16.1 8.1 2.1 2 0 0 2 2 2 1 PHD-finger Prok-RING_1 PF14446.6 EGC38955.1 - 0.96 9.4 4.7 2.8 7.9 4.7 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Zf_RING PF16744.5 EGC38955.1 - 2.6 8.2 5.9 9.2 6.5 3.2 2.7 2 0 0 2 2 2 0 KIAA1045 RING finger ADK_lid PF05191.14 EGC38955.1 - 3.1 7.9 4.7 21 5.2 5.0 2.4 2 0 0 2 2 2 0 Adenylate kinase, active site lid zf-RING_2 PF13639.6 EGC38955.1 - 4.2 7.8 6.4 12 6.3 6.4 1.9 1 0 0 1 1 1 0 Ring finger domain Utp11 PF03998.13 EGC38956.1 - 3.2e-48 164.8 16.9 3.6e-48 164.7 16.9 1.0 1 0 0 1 1 1 1 Utp11 protein Fib_alpha PF08702.10 EGC38956.1 - 9.4 6.4 9.3 1.5 9.0 5.3 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pyridoxal_deC PF00282.19 EGC38957.1 - 4.8e-15 55.2 0.1 6.1e-06 25.2 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_1 PF00667.20 EGC38958.1 - 7.7e-60 202.2 0.0 1.3e-59 201.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGC38958.1 - 1.8e-32 112.5 0.2 4.9e-32 111.1 0.1 1.8 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGC38958.1 - 4.6e-19 69.1 0.0 1.4e-18 67.5 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain adh_short PF00106.25 EGC38958.1 - 1.3e-06 28.0 0.2 3.3e-06 26.7 0.2 1.6 1 1 0 1 1 1 1 short chain dehydrogenase RepC PF06504.11 EGC38958.1 - 0.018 14.3 0.1 0.26 10.4 0.1 2.1 2 0 0 2 2 2 0 Replication protein C (RepC) PARP_reg PF02877.14 EGC38958.1 - 0.14 12.2 0.3 0.47 10.6 0.1 2.0 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain Pro-kuma_activ PF09286.11 EGC38959.1 - 1.9e-30 106.0 0.1 1.9e-30 106.0 0.1 1.9 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.22 EGC38959.1 - 0.019 14.2 0.0 0.067 12.4 0.0 1.8 1 1 0 1 1 1 0 Subtilase family V_ATPase_I PF01496.19 EGC38959.1 - 4.6 5.0 18.6 6.5 4.5 18.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SID-1_RNA_chan PF13965.6 EGC38959.1 - 5.2 5.4 7.5 8.6 4.6 7.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 LMBR1 PF04791.16 EGC38959.1 - 9.1 5.1 13.3 15 4.3 13.3 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein Pmp3 PF01679.17 EGC38960.1 - 2.1e-16 59.8 12.8 2.3e-16 59.7 12.8 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF872 PF05915.12 EGC38960.1 - 0.58 10.3 4.5 0.61 10.3 4.5 1.0 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Tail_VII PF17091.5 EGC38960.1 - 5.7 6.9 10.0 0.62 10.0 1.4 2.3 2 1 0 2 2 2 0 Inovirus G7P protein WBP-1 PF11669.8 EGC38961.1 - 0.21 12.2 1.5 0.48 11.1 0.1 2.1 2 0 0 2 2 2 0 WW domain-binding protein 1 DUF202 PF02656.15 EGC38961.1 - 0.22 12.0 10.0 0.56 10.7 1.1 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF202) Claudin_3 PF06653.11 EGC38961.1 - 0.27 11.2 14.1 14 5.6 10.2 3.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like Phage_holin_3_6 PF07332.11 EGC38961.1 - 8 6.5 10.0 41 4.3 10.0 2.0 1 1 0 1 1 1 0 Putative Actinobacterial Holin-X, holin superfamily III Peptidase_M1 PF01433.20 EGC38962.1 - 3.9e-80 268.5 0.4 8.3e-80 267.4 0.4 1.6 1 0 0 1 1 1 1 Peptidase family M1 domain ERAP1_C PF11838.8 EGC38962.1 - 1.2e-77 261.6 0.0 7.6e-77 258.9 0.0 2.2 2 1 1 3 3 3 1 ERAP1-like C-terminal domain Peptidase_M1_N PF17900.1 EGC38962.1 - 1.5e-53 181.8 2.3 3.1e-53 180.7 2.3 1.5 1 0 0 1 1 1 1 Peptidase M1 N-terminal domain BSP PF04450.12 EGC38962.1 - 0.14 11.9 0.1 6.7 6.4 0.0 2.4 2 0 0 2 2 2 0 Peptidase of plants and bacteria Peptidase_M61 PF05299.12 EGC38962.1 - 0.47 10.9 2.4 76 3.7 3.7 3.2 2 1 0 2 2 2 0 M61 glycyl aminopeptidase Ras PF00071.22 EGC38963.1 - 4.2e-49 166.3 0.0 4.8e-49 166.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC38963.1 - 1.6e-21 76.7 0.0 2.4e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC38963.1 - 1e-08 34.8 0.0 1.4e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC38963.1 - 0.0024 17.5 0.1 0.011 15.3 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGC38963.1 - 0.031 13.7 0.0 0.18 11.2 0.0 1.9 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC38963.1 - 0.041 14.0 0.0 0.063 13.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase TAN PF11640.8 EGC38963.1 - 0.066 13.3 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 Telomere-length maintenance and DNA damage repair DDE_Tnp_1_assoc PF13808.6 EGC38963.1 - 0.14 12.2 0.0 0.28 11.2 0.0 1.5 1 0 0 1 1 1 0 DDE_Tnp_1-associated CX9C PF16860.5 EGC38964.1 - 0.0091 16.0 2.2 0.15 12.1 0.2 2.1 2 0 0 2 2 2 1 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, UPF0203 PF05254.12 EGC38964.1 - 0.019 15.2 3.2 0.062 13.6 3.2 1.7 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) GST_C_3 PF14497.6 EGC38964.1 - 0.046 13.9 0.0 2.2 8.6 0.0 2.0 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain COX6B PF02297.17 EGC38964.1 - 0.054 13.7 2.7 0.18 12.1 2.8 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb DUF3128 PF11326.8 EGC38964.1 - 0.061 13.7 3.0 3.2 8.2 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) CHCH PF06747.13 EGC38964.1 - 0.1 12.8 3.1 1.2 9.4 0.1 2.2 2 0 0 2 2 2 0 CHCH domain FNIP PF05725.12 EGC38965.1 - 7.4e-54 179.7 42.2 9.9e-11 41.6 1.5 8.0 6 2 3 9 9 9 8 FNIP Repeat DUF3430 PF11912.8 EGC38966.1 - 9.9e-10 38.8 30.6 1.5e-09 38.3 30.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) WD40 PF00400.32 EGC38967.1 - 3.4e-08 34.0 0.6 0.012 16.5 0.0 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat DUF5117 PF17148.4 EGC38967.1 - 1.8 8.4 12.4 0.34 10.7 6.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF5117) DSPc PF00782.20 EGC38968.1 - 1.1e-28 99.7 0.6 1.1e-28 99.7 0.6 2.3 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.6 EGC38968.1 - 9.1e-24 83.0 29.7 1.1e-09 37.9 2.1 4.9 2 2 2 4 4 4 4 Leucine rich repeat LRR_4 PF12799.7 EGC38968.1 - 1e-14 54.4 50.0 2.5e-05 24.5 0.2 7.2 6 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGC38968.1 - 8.1e-05 22.4 18.4 1.2 9.4 0.1 7.7 7 0 0 7 7 7 2 Leucine Rich repeat SprA-related PF12118.8 EGC38968.1 - 0.00042 19.6 13.0 0.00067 18.9 13.0 1.3 1 0 0 1 1 1 1 SprA-related family Y_phosphatase PF00102.27 EGC38968.1 - 0.0024 17.5 1.5 0.01 15.4 0.0 2.2 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DUF2015 PF09435.10 EGC38968.1 - 0.05 13.5 0.0 0.16 11.8 0.0 1.8 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF2015) PTPlike_phytase PF14566.6 EGC38968.1 - 0.12 12.5 0.0 0.12 12.5 0.0 2.6 2 0 0 2 2 2 0 Inositol hexakisphosphate CDC27 PF09507.10 EGC38968.1 - 0.16 11.3 24.3 0.22 10.9 24.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 CoA_transf_3 PF02515.17 EGC38969.1 - 4.7e-118 394.5 0.0 5.4e-118 394.3 0.0 1.0 1 0 0 1 1 1 1 CoA-transferase family III ANAPC4_WD40 PF12894.7 EGC38970.1 - 7.3e-05 23.0 7.5 0.09 13.1 0.2 3.9 1 1 4 5 5 5 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC38970.1 - 0.00012 22.8 14.1 0.17 12.8 0.1 6.0 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.6 EGC38970.1 - 0.0028 17.6 4.7 0.042 13.9 0.2 4.1 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region CBM_48 PF02922.18 EGC38970.1 - 0.11 12.9 0.0 0.25 11.7 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Ten_N PF06484.12 EGC38970.1 - 0.19 11.6 3.6 0.19 11.5 2.1 1.8 2 0 0 2 2 2 0 Teneurin Intracellular Region ANAPC4_WD40 PF12894.7 EGC38971.1 - 6.5e-09 36.0 0.9 0.19 12.0 0.1 3.5 2 2 1 3 3 3 3 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.32 EGC38971.1 - 6.5e-07 30.0 18.4 0.045 14.6 0.9 5.8 6 0 0 6 6 6 3 WD domain, G-beta repeat Utp8 PF10395.9 EGC38971.1 - 0.0018 16.9 0.9 0.0091 14.5 0.1 2.1 1 1 2 3 3 3 1 Utp8 family eIF2A PF08662.11 EGC38971.1 - 0.019 14.8 1.4 0.5 10.2 0.9 2.4 1 1 1 2 2 2 0 Eukaryotic translation initiation factor eIF2A RPN7 PF10602.9 EGC38972.1 - 1.2e-57 194.5 1.3 1.8e-57 193.8 1.3 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.27 EGC38972.1 - 6.1e-17 62.1 0.1 2.7e-16 60.0 0.0 2.2 2 0 0 2 2 2 1 PCI domain Sec3_C_2 PF15278.6 EGC38972.1 - 0.02 15.2 0.1 0.053 13.9 0.1 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit ToxN_toxin PF13958.6 EGC38972.1 - 0.036 14.3 1.7 0.72 10.1 0.1 2.2 2 0 0 2 2 2 0 Toxin ToxN, type III toxin-antitoxin system Ctr PF04145.15 EGC38973.1 - 4.2e-28 98.8 1.1 5.4e-28 98.5 1.1 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.6 EGC38973.1 - 0.016 15.3 1.4 0.033 14.3 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4229) DUF2207 PF09972.9 EGC38973.1 - 0.11 11.2 1.2 0.13 11.0 1.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FeoB_associated PF12669.7 EGC38973.1 - 3.5 8.1 5.3 4.2 7.9 0.7 2.5 2 1 0 2 2 2 0 FeoB-associated Cys-rich membrane protein Cellulase PF00150.18 EGC38974.1 - 1.6e-32 113.1 4.4 1.6e-32 113.1 4.4 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM49 PF09478.10 EGC38974.1 - 4.1e-17 62.3 0.7 4.1e-17 62.3 0.7 2.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 WGG PF10273.9 EGC38975.1 - 4.6e-21 75.3 0.1 1.2e-20 73.9 0.1 1.8 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.7 EGC38975.1 - 0.0062 16.7 2.0 0.0062 16.7 2.0 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain USP8_interact PF08941.10 EGC38975.1 - 0.0081 16.0 2.6 0.012 15.4 2.6 1.3 1 0 0 1 1 1 1 USP8 interacting DUF5357 PF17310.2 EGC38975.1 - 0.027 13.0 5.9 0.044 12.3 5.9 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5357) Metallopep PF12044.8 EGC38975.1 - 0.37 9.3 4.5 0.54 8.8 4.5 1.2 1 0 0 1 1 1 0 Putative peptidase family DUF1003 PF06210.11 EGC38975.1 - 6.7 6.9 8.7 15 5.8 8.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1003) Sec23_trunk PF04811.15 EGC38976.1 - 1.7e-19 70.3 1.2 2.5e-16 60.0 0.1 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.15 EGC38976.1 - 9.4e-17 60.7 0.1 2.2e-16 59.5 0.1 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGC38976.1 - 7.7e-08 32.3 1.7 1.7e-07 31.2 1.7 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EGC38976.1 - 0.01 16.5 1.1 0.028 15.2 0.0 2.3 2 0 0 2 2 2 0 Sec23/Sec24 beta-sandwich domain MucBP_2 PF17965.1 EGC38976.1 - 0.12 12.9 0.7 0.31 11.6 0.7 1.6 1 0 0 1 1 1 0 Mucin binding domain C1_1 PF00130.22 EGC38976.1 - 0.27 11.1 2.3 0.56 10.1 2.3 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zinc-ribbons_6 PF07191.12 EGC38976.1 - 0.54 10.3 2.6 1.1 9.2 2.6 1.4 1 0 0 1 1 1 0 zinc-ribbons AAA_28 PF13521.6 EGC38977.1 - 1.4e-29 103.5 0.0 1.5e-29 103.3 0.0 1.0 1 0 0 1 1 1 1 AAA domain ATP-synt_ab PF00006.25 EGC38977.1 - 0.21 11.2 0.0 0.37 10.4 0.0 1.6 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain F-box PF00646.33 EGC38978.1 - 0.0084 16.0 2.3 0.044 13.7 0.4 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.7 EGC38978.1 - 0.013 15.4 0.1 0.036 13.9 0.1 1.8 1 0 0 1 1 1 0 F-box-like Syntaxin-6_N PF09177.11 EGC38979.1 - 2 9.0 9.3 0.58 10.7 3.8 2.5 2 2 0 2 2 2 0 Syntaxin 6, N-terminal DUF848 PF05852.11 EGC38979.1 - 2.6 8.1 9.0 2.1 8.4 4.6 2.1 2 0 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) Tyr-DNA_phospho PF06087.12 EGC38981.1 - 4.5e-30 104.9 21.0 4.6e-25 88.4 1.0 3.2 2 1 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Cellulase PF00150.18 EGC38983.1 - 4.1e-29 101.9 0.3 6.6e-29 101.2 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_5_C PF18564.1 EGC38983.1 - 5.2e-16 59.0 1.9 9.4e-16 58.1 1.9 1.4 1 0 0 1 1 1 1 Glycoside hydrolase family 5 C-terminal domain Glyco_hydro_42 PF02449.15 EGC38983.1 - 0.018 14.4 0.0 0.033 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase DUF1415 PF07209.12 EGC38983.1 - 0.092 12.5 0.0 0.23 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1415) Raptor_N PF14538.6 EGC38984.1 - 2.3e-72 241.7 0.1 4.9e-72 240.7 0.1 1.6 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.32 EGC38984.1 - 1.8e-12 47.6 4.1 1.2 10.1 0.0 7.6 6 1 1 7 7 7 3 WD domain, G-beta repeat HEAT PF02985.22 EGC38984.1 - 5.7e-10 38.6 7.0 0.0073 16.5 0.1 5.9 6 0 0 6 6 6 2 HEAT repeat Cnd1 PF12717.7 EGC38984.1 - 1.8e-07 31.3 0.1 0.00087 19.4 0.0 3.4 2 1 1 3 3 3 2 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.6 EGC38984.1 - 2.3e-06 27.9 0.5 0.043 14.2 0.2 3.1 2 1 1 3 3 3 2 HEAT repeats ANAPC4_WD40 PF12894.7 EGC38984.1 - 4.3e-06 26.9 0.0 1.3 9.3 0.0 4.1 3 1 1 4 4 4 2 Anaphase-promoting complex subunit 4 WD40 domain HEAT_EZ PF13513.6 EGC38984.1 - 0.01 16.3 2.6 1.6 9.3 0.2 3.4 2 1 1 3 3 3 0 HEAT-like repeat BING4CT PF08149.11 EGC38984.1 - 0.082 12.7 0.0 3 7.7 0.0 2.9 2 0 0 2 2 2 0 BING4CT (NUC141) domain CDC45 PF02724.14 EGC38984.1 - 1.1 7.5 8.8 1 7.6 4.1 2.1 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.22 EGC38984.1 - 3.9 6.6 8.5 32 3.6 0.0 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter EPL1 PF10513.9 EGC38984.1 - 9.3 6.6 24.2 1.1 9.7 7.6 2.8 3 0 0 3 3 3 0 Enhancer of polycomb-like ARD PF03079.14 EGC38984.1 - 9.8 6.3 7.3 24 5.1 7.3 1.7 1 0 0 1 1 1 0 ARD/ARD' family PRA1 PF03208.19 EGC38985.1 - 0.023 14.3 3.8 0.042 13.5 3.8 1.3 1 0 0 1 1 1 0 PRA1 family protein EF-hand_7 PF13499.6 EGC38985.1 - 0.028 14.9 0.1 0.11 13.0 0.1 2.1 1 0 0 1 1 1 0 EF-hand domain pair RhodobacterPufX PF11511.8 EGC38985.1 - 0.25 11.0 1.1 0.59 9.8 1.1 1.6 1 0 0 1 1 1 0 Intrinsic membrane protein PufX GTP_EFTU PF00009.27 EGC38986.1 - 3.8e-56 189.7 0.1 5.6e-56 189.2 0.1 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.17 EGC38986.1 - 3.6e-38 130.3 0.4 1.2e-37 128.6 0.0 2.1 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.25 EGC38986.1 - 5e-14 52.4 0.3 1.3e-13 51.2 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.23 EGC38986.1 - 2.5e-05 24.3 0.1 0.00057 19.9 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC38986.1 - 0.0099 15.2 0.0 0.018 14.4 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU_D4 PF14578.6 EGC38986.1 - 0.011 15.6 1.7 0.018 15.0 0.3 2.0 2 0 0 2 2 2 0 Elongation factor Tu domain 4 FeoB_N PF02421.18 EGC38986.1 - 0.16 11.5 0.3 1 8.9 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AMP-binding PF00501.28 EGC38987.1 - 4.7e-72 242.9 0.0 5.7e-72 242.6 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ACAS_N PF16177.5 EGC38987.1 - 1e-10 41.3 5.8 2.1e-10 40.4 5.8 1.5 1 0 0 1 1 1 1 Acetyl-coenzyme A synthetase N-terminus AMP-binding_C PF13193.6 EGC38987.1 - 0.00021 22.2 0.0 0.00044 21.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1947 PF09183.10 EGC38987.1 - 0.28 11.5 3.8 4.7 7.6 0.0 3.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) PTR2 PF00854.21 EGC38988.1 - 1e-93 314.4 10.5 1e-93 314.4 10.5 1.6 1 1 1 2 2 2 1 POT family DUF2070 PF09843.9 EGC38988.1 - 0.0037 15.6 0.7 0.0037 15.6 0.7 2.2 2 0 0 2 2 2 2 Predicted membrane protein (DUF2070) TM140 PF14985.6 EGC38988.1 - 0.073 12.6 5.3 2.6 7.5 0.1 2.9 3 0 0 3 3 3 0 TM140 protein family Phage_holin_3_6 PF07332.11 EGC38988.1 - 0.28 11.2 10.4 0.27 11.3 0.2 3.2 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III PTR2 PF00854.21 EGC38989.1 - 1.9e-91 306.9 14.6 1.9e-91 306.9 14.6 1.4 1 1 0 1 1 1 1 POT family DUF2070 PF09843.9 EGC38989.1 - 0.00054 18.4 2.4 0.00054 18.4 2.4 2.2 2 0 0 2 2 2 1 Predicted membrane protein (DUF2070) DUF5392 PF17370.2 EGC38989.1 - 0.06 13.4 0.0 0.06 13.4 0.0 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5392) TM140 PF14985.6 EGC38989.1 - 0.48 10.0 9.7 2.2 7.8 0.1 3.0 3 0 0 3 3 3 0 TM140 protein family Phage_holin_3_6 PF07332.11 EGC38989.1 - 9 6.4 19.8 0.4 10.7 2.8 3.5 4 0 0 4 4 4 0 Putative Actinobacterial Holin-X, holin superfamily III DUF11 PF01345.18 EGC38990.1 - 0.2 12.0 2.5 5.5 7.4 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function DUF11 TMEM141 PF15110.6 EGC38990.1 - 0.28 11.8 0.2 0.28 11.8 0.2 2.6 2 1 1 3 3 3 0 TMEM141 protein family AAA_12 PF13087.6 EGC38991.1 - 1.5e-22 80.2 2.6 1.5e-22 80.2 2.6 3.0 2 1 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EGC38991.1 - 1.9e-16 60.7 1.6 1.2e-15 58.0 0.7 2.4 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC38991.1 - 2.4e-06 27.4 0.0 4.3e-06 26.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain ResIII PF04851.15 EGC38991.1 - 0.0011 19.1 1.9 0.0052 16.8 1.6 2.3 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SRP54 PF00448.22 EGC38991.1 - 0.0018 17.9 0.4 0.11 12.2 0.2 2.9 3 0 0 3 3 3 1 SRP54-type protein, GTPase domain MeaB PF03308.16 EGC38991.1 - 0.021 13.8 0.0 0.044 12.8 0.0 1.5 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Ribonuc_red_sm PF00268.21 EGC38991.1 - 0.027 13.9 2.1 0.042 13.3 0.7 1.9 2 0 0 2 2 2 0 Ribonucleotide reductase, small chain AAA_22 PF13401.6 EGC38991.1 - 0.028 14.7 0.6 0.19 12.0 0.0 2.6 3 1 0 3 3 2 0 AAA domain AAA_19 PF13245.6 EGC38991.1 - 0.035 14.5 0.0 0.081 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGC38991.1 - 0.036 14.5 1.7 6.9 7.1 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_7 PF12775.7 EGC38991.1 - 0.059 12.9 0.5 1 8.8 0.2 2.9 2 1 1 3 3 3 0 P-loop containing dynein motor region YopH_N PF09013.10 EGC38991.1 - 0.077 13.3 0.2 4.5 7.6 0.1 2.7 2 0 0 2 2 2 0 YopH, N-terminal Myofilin PF15929.5 EGC38991.1 - 0.11 12.9 0.0 0.22 11.9 0.0 1.5 1 0 0 1 1 1 0 Myofilin DUF3006 PF11213.8 EGC38991.1 - 0.18 12.1 0.6 4.7 7.5 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) Rotamase PF00639.21 EGC38991.1 - 0.21 12.6 1.7 0.42 11.6 0.4 2.1 2 0 0 2 2 2 0 PPIC-type PPIASE domain AAA_31 PF13614.6 EGC38991.1 - 0.26 11.2 10.2 2.3 8.1 10.2 2.4 1 1 0 1 1 1 0 AAA domain UvrD-helicase PF00580.21 EGC38991.1 - 2.1 7.8 15.4 32 3.9 14.3 3.0 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain CbiA PF01656.23 EGC38991.1 - 3.5 7.7 9.4 0.25 11.4 1.5 2.9 3 2 0 3 3 3 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF3439 PF11921.8 EGC38992.1 - 0.49 10.4 4.7 0.98 9.4 4.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myotub-related PF06602.14 EGC38993.1 - 3.2e-129 430.9 0.0 7.2e-129 429.7 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Ank_2 PF12796.7 EGC38993.1 - 4.5e-24 84.9 0.9 1.6e-11 44.6 0.1 3.1 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGC38993.1 - 4.3e-21 74.3 0.1 2e-05 24.8 0.1 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.6 EGC38993.1 - 1.1e-20 73.4 7.2 9.1e-10 38.6 0.0 5.6 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.6 EGC38993.1 - 3.6e-20 72.1 1.1 8.1e-09 35.9 0.1 4.6 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC38993.1 - 1.3e-19 68.2 0.4 0.00056 20.2 0.0 6.2 5 0 0 5 5 5 5 Ankyrin repeat GRAM PF02893.20 EGC38993.1 - 0.0022 17.8 1.6 0.008 16.1 0.1 2.6 2 0 0 2 2 2 1 GRAM domain Y_phosphatase3 PF13350.6 EGC38993.1 - 0.0094 15.9 0.0 0.19 11.7 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGC38993.1 - 0.022 14.5 0.0 0.022 14.5 0.0 3.0 3 0 0 3 3 3 0 Dual specificity phosphatase, catalytic domain 3-PAP PF12578.8 EGC38993.1 - 2.5 7.8 4.9 0.46 10.2 0.1 2.3 2 0 0 2 2 2 0 Myotubularin-associated protein F-box-like PF12937.7 EGC38994.1 - 0.00033 20.5 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like Dynactin_p22 PF07426.11 EGC38994.1 - 0.0064 16.4 1.4 0.028 14.3 0.9 2.1 2 0 0 2 2 2 1 Dynactin subunit p22 F-box PF00646.33 EGC38994.1 - 0.17 11.8 0.1 0.36 10.8 0.1 1.6 1 0 0 1 1 1 0 F-box domain Branch PF02485.21 EGC38995.1 - 1.6e-10 41.0 0.6 3.6e-10 39.8 0.6 1.6 1 1 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.32 EGC38996.1 - 1.5e-39 133.2 46.7 4.3e-06 27.4 2.3 8.9 8 0 0 8 8 8 6 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC38996.1 - 1.3e-12 47.8 10.7 0.052 13.8 0.1 6.6 1 1 4 6 6 6 5 Anaphase-promoting complex subunit 4 WD40 domain F-box-like PF12937.7 EGC38996.1 - 8.5e-10 38.4 0.2 1.7e-09 37.4 0.2 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.8 EGC38996.1 - 3.2e-08 32.7 15.9 0.097 11.3 0.4 6.2 4 2 2 6 6 6 5 Nucleoporin Nup120/160 F-box PF00646.33 EGC38996.1 - 6.6e-08 32.3 1.6 7.5e-08 32.1 0.1 1.9 2 0 0 2 2 2 1 F-box domain F-box_5 PF18511.1 EGC38996.1 - 0.17 11.5 0.8 0.45 10.1 0.8 1.7 1 0 0 1 1 1 0 F-box Selenoprotein_S PF06936.11 EGC38997.1 - 5.2 6.8 9.9 10 5.9 9.9 1.4 1 0 0 1 1 1 0 Selenoprotein S (SelS) Sec63 PF02889.16 EGC38998.1 - 6.5e-162 536.7 5.8 1e-84 283.7 0.4 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.29 EGC38998.1 - 1.1e-44 152.4 2.6 4.1e-23 82.1 0.1 3.9 3 0 0 3 3 3 2 DEAD/DEAH box helicase Helicase_PWI PF18149.1 EGC38998.1 - 4.2e-31 107.4 6.8 3.1e-30 104.6 4.7 3.1 3 0 0 3 3 3 1 N-terminal helicase PWI domain ResIII PF04851.15 EGC38998.1 - 2e-24 86.5 3.5 2.6e-11 43.8 0.0 3.7 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGC38998.1 - 1.9e-15 57.2 0.3 5.2e-07 30.0 0.0 4.8 3 2 0 3 3 3 2 Helicase conserved C-terminal domain AAA_30 PF13604.6 EGC38998.1 - 1.1e-05 25.2 0.0 0.0033 17.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain SMN PF06003.12 EGC38998.1 - 2.2 7.5 7.7 6 6.0 7.7 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) CH PF00307.31 EGC39000.1 - 1.3e-46 157.3 7.2 2.3e-17 63.1 0.2 3.8 3 0 0 3 3 3 3 Calponin homology (CH) domain RhoGEF PF00621.20 EGC39000.1 - 1.4e-44 152.5 10.1 2.8e-44 151.6 6.1 2.9 2 0 0 2 2 2 1 RhoGEF domain CAMSAP_CH PF11971.8 EGC39000.1 - 3e-11 43.0 1.7 0.039 13.8 0.1 4.2 3 0 0 3 3 3 3 CAMSAP CH domain PH PF00169.29 EGC39000.1 - 1.4e-06 28.7 2.8 0.00039 20.9 2.8 3.3 1 1 0 1 1 1 1 PH domain CDC24 PF06395.11 EGC39000.1 - 4.8e-05 23.5 5.5 0.26 11.5 0.3 4.0 4 0 0 4 4 4 2 CDC24 Calponin CH_2 PF06294.11 EGC39000.1 - 0.012 15.7 0.1 9.2 6.5 0.0 3.9 3 0 0 3 3 3 0 CH-like domain in sperm protein Plant_zn_clust PF10533.9 EGC39000.1 - 0.11 12.5 0.1 0.33 11.0 0.1 1.8 1 0 0 1 1 1 0 Plant zinc cluster domain CRAL_TRIO_2 PF13716.6 EGC39001.1 - 7.2e-40 136.3 0.2 1e-39 135.8 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.20 EGC39001.1 - 8.3e-07 28.9 0.3 4.7e-06 26.4 0.3 1.9 1 1 0 1 1 1 1 CRAL/TRIO domain SPC25 PF06703.11 EGC39002.1 - 2.7e-23 82.5 0.5 7.8e-13 48.5 0.0 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) Paf1 PF03985.13 EGC39003.1 - 4.1e-56 190.8 13.8 4.1e-56 190.8 13.8 2.0 2 0 0 2 2 2 1 Paf1 IP_trans PF02121.18 EGC39003.1 - 1.4 8.4 8.4 0.14 11.7 3.8 1.6 2 0 0 2 2 2 0 Phosphatidylinositol transfer protein Zip PF02535.22 EGC39003.1 - 9.2 5.4 6.8 2 7.6 3.6 1.5 2 0 0 2 2 2 0 ZIP Zinc transporter PPI_Ypi1 PF07491.11 EGC39004.1 - 9.1e-23 79.9 1.0 9.1e-23 79.9 1.0 2.1 2 0 0 2 2 2 1 Protein phosphatase inhibitor VIR_N PF15912.5 EGC39004.1 - 0.0047 16.6 6.7 0.0054 16.4 6.7 1.0 1 0 0 1 1 1 1 Virilizer, N-terminal DTHCT PF08070.11 EGC39004.1 - 2.3 9.0 11.2 0.49 11.2 3.7 2.0 1 1 1 2 2 2 0 DTHCT (NUC029) region Ras PF00071.22 EGC39005.1 - 7.7e-61 204.4 0.8 9.1e-61 204.2 0.8 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39005.1 - 5.4e-35 120.2 0.1 8e-35 119.7 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39005.1 - 4.3e-14 52.3 0.2 5.4e-14 52.0 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC39005.1 - 8e-08 32.4 0.1 1.2e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC39005.1 - 1e-06 28.8 0.1 0.01 15.8 0.0 2.1 2 0 0 2 2 2 2 RsgA GTPase GTP_EFTU PF00009.27 EGC39005.1 - 1e-05 25.2 0.2 4.1e-05 23.2 0.1 1.8 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.12 EGC39005.1 - 0.0001 21.8 0.2 0.00014 21.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_16 PF13191.6 EGC39005.1 - 0.00027 21.4 0.0 0.00047 20.6 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain PduV-EutP PF10662.9 EGC39005.1 - 0.00046 19.9 0.0 0.0011 18.7 0.1 1.7 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGC39005.1 - 0.00069 19.1 0.1 0.00097 18.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.18 EGC39005.1 - 0.0043 16.6 0.4 0.028 13.9 0.4 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_22 PF13401.6 EGC39005.1 - 0.0044 17.3 0.1 0.029 14.6 0.1 2.1 1 1 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGC39005.1 - 0.0064 16.2 0.2 0.017 14.8 0.2 1.8 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.27 EGC39005.1 - 0.016 15.7 0.2 0.032 14.8 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_32 PF13654.6 EGC39005.1 - 0.037 12.8 0.1 0.23 10.2 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_7 PF12775.7 EGC39005.1 - 0.044 13.3 0.0 0.087 12.3 0.0 1.4 1 0 0 1 1 1 0 P-loop containing dynein motor region Ploopntkinase3 PF18751.1 EGC39005.1 - 0.062 13.2 0.0 0.83 9.5 0.0 2.1 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 TniB PF05621.11 EGC39005.1 - 0.081 12.3 0.0 0.2 11.0 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_28 PF13521.6 EGC39005.1 - 0.084 13.1 0.5 0.33 11.2 0.1 1.9 1 1 0 2 2 2 0 AAA domain MCM PF00493.23 EGC39005.1 - 0.091 11.8 0.0 0.16 11.0 0.0 1.5 1 1 0 1 1 1 0 MCM P-loop domain AAA_14 PF13173.6 EGC39005.1 - 0.11 12.5 0.2 0.3 11.1 0.2 1.8 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.6 EGC39005.1 - 0.2 11.4 1.1 0.33 10.7 0.4 1.6 1 1 0 1 1 1 0 AAA domain, putative AbiEii toxin, Type IV TA system Fer2_3 PF13085.6 EGC39006.1 - 5e-33 113.4 0.0 9.6e-33 112.5 0.0 1.5 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.6 EGC39006.1 - 2.5e-09 37.5 3.7 2.5e-09 37.5 3.7 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.6 EGC39006.1 - 2.3e-08 34.4 10.3 3.1e-08 34.0 6.8 2.5 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_10 PF13237.6 EGC39006.1 - 6.2e-08 32.6 2.6 6.2e-08 32.6 2.6 2.1 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer2 PF00111.27 EGC39006.1 - 0.003 17.5 4.6 0.0065 16.4 0.4 2.3 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.6 EGC39006.1 - 0.22 12.5 10.5 1.4 9.9 0.1 3.0 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_18 PF13746.6 EGC39006.1 - 0.73 10.0 8.2 0.88 9.8 0.2 2.7 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_9 PF13187.6 EGC39006.1 - 1.2 9.3 15.4 2.2 8.5 10.5 3.0 2 1 1 3 3 3 0 4Fe-4S dicluster domain Phage_DsbA PF11126.8 EGC39007.1 - 0.031 14.5 1.2 1.7 8.9 0.0 2.9 2 2 1 3 3 3 0 Transcriptional regulator DsbA CYSTM PF12734.7 EGC39008.1 - 0.022 15.1 1.6 0.022 15.1 1.6 4.8 1 1 1 2 2 2 0 Cysteine-rich TM module stress tolerance DUF810 PF05664.11 EGC39009.1 - 3.7e-16 58.8 9.9 2e-14 53.1 5.7 2.2 2 0 0 2 2 2 2 Plant family of unknown function (DUF810) 4HB PF17947.1 EGC39009.1 - 0.049 13.7 0.1 0.26 11.4 0.0 2.2 2 0 0 2 2 2 0 Four helical bundle domain Steroid_dh PF02544.16 EGC39010.1 - 8.7e-43 145.9 1.1 1.6e-42 145.0 1.1 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.13 EGC39010.1 - 0.0023 18.3 1.2 0.004 17.5 0.1 1.9 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.12 EGC39010.1 - 0.0055 16.3 0.5 0.0083 15.7 0.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2701 PF10857.8 EGC39011.1 - 0.066 13.3 1.3 0.066 13.3 1.3 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2701) Sel1 PF08238.12 EGC39012.1 - 1.2e-32 111.6 27.4 4.2e-05 24.1 0.2 11.7 12 0 0 12 12 12 8 Sel1 repeat TPR_19 PF14559.6 EGC39012.1 - 0.0069 16.9 0.9 2.6 8.6 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF4834 PF16118.5 EGC39012.1 - 0.016 16.2 1.5 0.016 16.2 1.5 5.2 4 1 1 5 5 5 0 Domain of unknown function (DUF4834) TPR_7 PF13176.6 EGC39012.1 - 0.034 14.2 2.2 1 9.5 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat UPF0239 PF06783.11 EGC39012.1 - 0.037 14.2 0.1 0.037 14.2 0.1 3.1 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0239) Conotoxin PF02950.17 EGC39012.1 - 0.076 14.0 0.1 0.076 14.0 0.1 3.2 3 0 0 3 3 3 0 Conotoxin GRP PF07172.11 EGC39012.1 - 0.32 11.7 0.0 0.32 11.7 0.0 3.3 3 0 0 3 3 3 0 Glycine rich protein family TPR_16 PF13432.6 EGC39012.1 - 1.4 9.6 3.5 1.1e+02 3.5 0.1 3.8 3 1 1 4 4 4 0 Tetratricopeptide repeat Sel1 PF08238.12 EGC39013.1 - 6.9e-40 134.6 34.6 1.8e-05 25.2 1.4 11.5 12 0 0 12 12 12 9 Sel1 repeat EphA2_TM PF14575.6 EGC39013.1 - 0.052 14.4 0.1 16 6.5 0.0 3.3 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain Shisa PF13908.6 EGC39013.1 - 0.062 13.5 0.3 0.062 13.5 0.3 3.3 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator Chordopox_A33R PF05966.12 EGC39013.1 - 0.12 11.6 5.1 0.62 9.3 2.2 2.5 1 1 1 2 2 2 0 Chordopoxvirus A33R protein TPR_6 PF13174.6 EGC39013.1 - 0.32 11.7 6.2 1.1e+02 3.7 0.1 5.8 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF2500 PF10694.9 EGC39013.1 - 0.82 10.2 4.0 4.6 7.8 0.8 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2500) Connexin PF00029.19 EGC39013.1 - 9.7 5.9 7.9 0.42 10.3 1.3 2.0 1 1 1 2 2 2 0 Connexin Mago_nashi PF02792.14 EGC39015.1 - 5.2e-72 240.6 0.8 5.2e-72 240.6 0.8 1.4 2 0 0 2 2 2 1 Mago nashi protein DUF3506 PF12014.8 EGC39015.1 - 0.11 12.5 0.1 0.21 11.6 0.1 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3506) PWI PF01480.17 EGC39016.1 - 5.1e-13 49.1 2.2 5.1e-13 49.1 2.2 2.3 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.22 EGC39016.1 - 4.1e-06 26.5 0.0 9.9e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Metallophos PF00149.28 EGC39017.1 - 6.2e-15 56.2 0.7 6.2e-15 56.2 0.7 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SapB_2 PF03489.17 EGC39017.1 - 0.0031 17.6 3.6 0.0067 16.5 1.0 2.6 2 0 0 2 2 2 1 Saposin-like type B, region 2 FHA PF00498.26 EGC39018.1 - 4.9e-19 68.5 0.0 1.4e-18 67.0 0.0 1.8 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC39018.1 - 1.1e-08 35.3 0.0 5.7e-08 33.0 0.0 2.1 2 0 0 2 2 2 1 Inner membrane component of T3SS, cytoplasmic domain ALAD PF00490.21 EGC39019.1 - 3.9e-121 404.1 0.0 4.4e-121 403.9 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Ras PF00071.22 EGC39020.1 - 8.9e-41 139.2 0.0 1.2e-40 138.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39020.1 - 1.5e-29 102.7 0.0 2.6e-29 101.9 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39020.1 - 2.7e-12 46.5 0.0 3.6e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39020.1 - 1.8e-06 27.5 0.0 3.4e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGC39020.1 - 2.9e-06 26.8 0.0 4.4e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGC39020.1 - 0.00049 19.7 0.0 0.004 16.7 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC39020.1 - 0.00054 20.0 0.0 0.00095 19.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.6 EGC39020.1 - 0.045 13.5 0.0 0.062 13.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain TniB PF05621.11 EGC39020.1 - 0.054 12.9 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Bacterial TniB protein PduV-EutP PF10662.9 EGC39020.1 - 0.073 12.8 0.0 1 9.1 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_7 PF12775.7 EGC39020.1 - 0.085 12.4 0.0 0.15 11.5 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region TsaE PF02367.17 EGC39020.1 - 0.1 12.6 0.0 0.24 11.4 0.0 1.6 1 1 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE EBP PF05241.12 EGC39021.1 - 9.6e-43 145.7 10.2 1.1e-42 145.5 10.2 1.0 1 0 0 1 1 1 1 Emopamil binding protein RRM_1 PF00076.22 EGC39022.1 - 2e-13 49.9 0.3 4.5e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGC39022.1 - 4.8e-10 40.1 0.2 1.1e-09 39.0 0.2 1.7 1 0 0 1 1 1 1 RNA polymerase II-binding domain. Macoilin PF09726.9 EGC39022.1 - 1 7.8 5.2 1.4 7.4 5.2 1.1 1 0 0 1 1 1 0 Macoilin family DUF3446 PF11928.8 EGC39022.1 - 8.1 6.8 14.1 9.3 6.6 1.4 3.0 2 0 0 2 2 2 0 Early growth response N-terminal domain HATPase_c PF02518.26 EGC39023.1 - 6.2e-24 84.7 0.4 1.9e-23 83.1 0.4 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.24 EGC39023.1 - 2.4e-16 59.9 0.4 9.7e-16 57.9 0.4 2.2 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.25 EGC39023.1 - 1.6e-15 56.9 0.0 3.5e-15 55.8 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.7 EGC39023.1 - 3.1e-07 30.3 0.0 7.4e-07 29.0 0.0 1.6 1 0 0 1 1 1 1 PAS domain PAS PF00989.25 EGC39023.1 - 0.02 14.9 0.0 0.062 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold DSPc PF00782.20 EGC39024.1 - 1.1e-30 106.2 0.1 1.4e-30 105.8 0.1 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC39024.1 - 5.3e-05 22.9 0.0 7.1e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.13 EGC39024.1 - 0.0034 17.0 0.1 0.0057 16.2 0.1 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Rad52_Rad22 PF04098.15 EGC39025.1 - 4.1e-46 156.7 0.0 6.1e-46 156.1 0.0 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Cofilin_ADF PF00241.20 EGC39026.1 - 1.7e-12 47.2 0.0 1.9e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Filamin PF00630.19 EGC39028.1 - 3.6e-128 419.6 16.4 3.9e-23 82.2 0.2 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.31 EGC39028.1 - 6e-41 139.0 0.4 6e-22 77.9 0.4 2.2 2 0 0 2 2 2 2 Calponin homology (CH) domain Invasin_D3 PF09134.10 EGC39028.1 - 3.4e-24 85.0 6.1 0.0015 18.8 0.0 6.3 6 0 0 6 6 6 6 Invasin, domain 3 Big_6 PF17936.1 EGC39028.1 - 2.3e-08 34.2 11.5 3.3 8.0 0.0 7.0 7 0 0 7 7 7 3 Bacterial Ig domain YtkA PF13115.6 EGC39028.1 - 5.5e-08 33.3 9.9 1.9 9.1 0.2 6.4 6 0 0 6 6 6 3 YtkA-like Y_Y_Y PF07495.13 EGC39028.1 - 4.2e-07 29.8 7.8 0.012 15.6 0.0 6.3 8 0 0 8 8 8 2 Y_Y_Y domain CAMSAP_CH PF11971.8 EGC39028.1 - 3.8e-06 26.7 0.2 0.099 12.5 0.0 2.8 3 0 0 3 3 3 2 CAMSAP CH domain DUF5060 PF16586.5 EGC39028.1 - 1.3e-05 25.5 0.0 0.28 11.6 0.0 4.3 4 0 0 4 4 4 1 Domain of unknown function (DUF5060) PKD PF00801.20 EGC39028.1 - 0.0013 18.5 0.2 0.099 12.5 0.0 3.5 3 0 0 3 3 3 1 PKD domain Big_3_5 PF16640.5 EGC39028.1 - 0.0044 17.2 6.8 21 5.4 0.0 5.3 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Neurexophilin PF06312.12 EGC39028.1 - 0.018 14.5 0.1 43 3.5 0.0 4.6 5 0 0 5 5 5 0 Neurexophilin Big_1 PF02369.16 EGC39028.1 - 0.022 14.7 6.7 16 5.6 0.0 5.6 6 2 0 6 6 5 0 Bacterial Ig-like domain (group 1) Big_3 PF07523.12 EGC39028.1 - 0.031 14.6 6.9 12 6.2 0.7 4.6 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 3) FixH PF05751.11 EGC39028.1 - 0.042 13.9 0.0 53 3.8 0.0 4.5 5 0 0 5 5 5 0 FixH Cadherin_5 PF17892.1 EGC39028.1 - 0.24 11.4 19.3 9.4 6.3 0.0 6.6 6 1 1 7 7 7 0 Cadherin-like domain Big_9 PF17963.1 EGC39028.1 - 1.2 9.9 27.4 0.49 11.2 0.4 6.6 6 2 0 6 6 6 0 Bacterial Ig domain DUF1541 PF07563.11 EGC39028.1 - 4.2 7.3 8.6 29 4.6 0.2 4.3 4 0 0 4 4 4 0 Protein of unknown function (DUF1541) zf-RVT PF13966.6 EGC39030.1 - 1.8e-06 28.6 0.9 3.9e-06 27.5 0.9 1.7 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FNIP PF05725.12 EGC39031.1 - 2.4e-10 40.4 1.6 3.5e-06 27.1 0.2 3.3 2 1 1 3 3 3 2 FNIP Repeat zf-RVT PF13966.6 EGC39031.1 - 7e-05 23.5 0.3 0.00024 21.8 0.3 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase FNIP PF05725.12 EGC39032.1 - 5.4e-105 343.4 58.0 1e-14 54.4 0.3 9.2 4 2 5 11 11 11 11 FNIP Repeat LRR_1 PF00560.33 EGC39032.1 - 0.0027 18.0 8.1 92 4.2 0.0 7.8 7 2 0 7 7 7 0 Leucine Rich Repeat FNIP PF05725.12 EGC39033.1 - 2.1e-54 181.4 27.4 3.9e-14 52.5 0.3 5.5 3 2 3 6 6 6 6 FNIP Repeat FNIP PF05725.12 EGC39034.1 - 1.9e-136 444.1 84.6 7.4e-16 58.0 1.5 10.2 3 2 9 13 13 13 13 FNIP Repeat UBA_6 PF18039.1 EGC39034.1 - 0.012 15.5 1.2 8.8 6.3 0.0 3.4 3 0 0 3 3 3 0 UBA-like domain ThiF PF00899.21 EGC39035.1 - 6.1e-106 353.2 0.0 3.9e-70 236.0 0.0 2.1 2 0 0 2 2 2 2 ThiF family UBA_e1_thiolCys PF10585.9 EGC39035.1 - 4.9e-92 308.4 4.6 4.9e-92 308.4 4.6 1.7 2 0 0 2 2 2 1 Ubiquitin-activating enzyme active site E1_UFD PF09358.10 EGC39035.1 - 4.3e-32 110.7 0.9 1.2e-31 109.2 0.9 1.9 1 0 0 1 1 1 1 Ubiquitin fold domain E1_FCCH PF16190.5 EGC39035.1 - 8.1e-28 96.4 0.4 2.3e-27 95.0 0.4 1.9 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 FCCH domain E1_4HB PF16191.5 EGC39035.1 - 1.6e-18 66.6 0.7 6e-18 64.8 0.7 2.1 1 0 0 1 1 1 1 Ubiquitin-activating enzyme E1 four-helix bundle NAD_binding_7 PF13241.6 EGC39035.1 - 0.011 16.2 0.6 0.13 12.7 0.1 3.0 3 0 0 3 3 3 0 Putative NAD(P)-binding DUF3669 PF12417.8 EGC39035.1 - 0.12 12.6 0.0 0.51 10.6 0.0 2.1 1 0 0 1 1 1 0 Zinc finger protein SseC PF04888.12 EGC39035.1 - 0.17 11.5 0.0 0.29 10.7 0.0 1.3 1 0 0 1 1 1 0 Secretion system effector C (SseC) like family Peptidase_M48 PF01435.18 EGC39036.1 - 1e-25 90.6 0.8 2e-25 89.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase family M48 Peptidase_M48_N PF16491.5 EGC39036.1 - 2.5e-11 43.8 16.9 8.8e-07 29.0 7.5 3.9 4 1 0 4 4 4 2 CAAX prenyl protease N-terminal, five membrane helices DCX PF03607.17 EGC39036.1 - 0.077 13.1 0.0 0.49 10.5 0.0 2.3 2 0 0 2 2 2 0 Doublecortin Peptidase_M56 PF05569.11 EGC39036.1 - 0.27 10.4 9.6 0.042 13.0 3.0 2.8 3 1 0 3 3 3 0 BlaR1 peptidase M56 MgtE PF01769.16 EGC39036.1 - 0.55 10.6 17.4 0.88 10.0 0.2 3.6 4 0 0 4 4 4 0 Divalent cation transporter DUF1279 PF06916.13 EGC39036.1 - 3.9 8.1 11.4 0.17 12.5 0.4 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1279) PLDc_N PF13396.6 EGC39038.1 - 1.6 8.7 5.0 2.3 8.2 5.0 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal FeoB_associated PF12669.7 EGC39038.1 - 6.9 7.2 8.3 12 6.4 8.3 1.4 1 0 0 1 1 1 0 FeoB-associated Cys-rich membrane protein 7TMR-DISM_7TM PF07695.11 EGC39041.1 - 0.0049 16.8 4.1 0.0071 16.3 4.1 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling PRY PF13765.6 EGC39041.1 - 0.028 14.0 0.4 1 9.1 0.0 2.6 3 0 0 3 3 3 0 SPRY-associated domain NrsF PF06532.11 EGC39041.1 - 0.035 13.8 0.0 0.054 13.2 0.0 1.3 1 0 0 1 1 1 0 Negative regulator of sigma F MRAP PF15183.6 EGC39041.1 - 2.9 7.9 9.1 1.6 8.7 0.3 3.1 1 1 1 3 3 3 0 Melanocortin-2 receptor accessory protein family Auxin_resp PF06507.13 EGC39044.1 - 0.24 11.7 0.3 0.63 10.3 0.0 1.8 2 0 0 2 2 2 0 Auxin response factor Period_C PF12114.8 EGC39044.1 - 1.1 8.8 5.2 1.5 8.3 5.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PIP5K PF01504.18 EGC39045.1 - 5.4e-71 239.0 7.7 5.4e-71 239.0 7.7 2.6 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase NEMP PF10225.9 EGC39045.1 - 0.035 13.8 4.5 0.054 13.2 2.8 2.0 2 0 0 2 2 2 0 NEMP family LAGLIDADG_WhiA PF14527.6 EGC39045.1 - 1.2 9.2 4.6 3.3 7.9 4.6 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain Kinesin PF00225.23 EGC39046.1 - 1.1e-31 110.0 0.0 1.1e-31 110.0 0.0 1.8 3 0 0 3 3 3 1 Kinesin motor domain Microtub_bd PF16796.5 EGC39046.1 - 1.1e-16 61.1 4.2 1.1e-16 61.0 0.0 2.6 2 1 0 2 2 2 1 Microtubule binding HNF_C PF09354.10 EGC39046.1 - 0.061 14.4 1.3 0.2 12.7 0.6 2.2 2 0 0 2 2 2 0 HNF3 C-terminal domain BRCT PF00533.26 EGC39047.1 - 7e-11 42.4 1.1 1.7e-10 41.2 1.1 1.6 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC39047.1 - 2.9e-07 30.8 0.7 7.1e-07 29.6 0.7 1.7 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain PTCB-BRCT PF12738.7 EGC39047.1 - 0.0042 17.0 0.1 0.008 16.1 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain Kinesin PF00225.23 EGC39048.1 - 1.7e-85 286.9 1.7 1.7e-85 286.9 1.7 3.4 4 1 0 4 4 4 1 Kinesin motor domain Microtub_bd PF16796.5 EGC39048.1 - 2.7e-24 85.8 0.0 2.7e-24 85.8 0.0 4.3 4 1 0 4 4 4 1 Microtubule binding DUF1192 PF06698.11 EGC39048.1 - 1.2 9.2 7.9 15 5.7 0.0 4.3 3 1 0 4 4 4 0 Protein of unknown function (DUF1192) MerR-DNA-bind PF09278.11 EGC39048.1 - 1.3 9.6 4.4 0.96 10.0 0.8 2.7 2 0 0 2 2 2 0 MerR, DNA binding FNIP PF05725.12 EGC39049.1 - 4.6e-40 135.5 22.9 6.1e-13 48.7 0.1 6.6 4 1 3 7 7 7 7 FNIP Repeat Copine PF07002.16 EGC39050.1 - 1.3e-29 103.2 0.1 1.2e-28 100.1 0.1 2.1 1 1 0 1 1 1 1 Copine C2 PF00168.30 EGC39050.1 - 5.1e-10 39.6 0.3 8.5e-05 22.8 0.0 2.3 2 0 0 2 2 2 2 C2 domain Adaptin_N PF01602.20 EGC39052.1 - 1.2e-114 383.8 18.8 1.2e-114 383.8 18.8 1.4 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.10 EGC39052.1 - 2.8e-56 189.8 0.3 6.2e-56 188.7 0.3 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain Coatomer_g_Cpla PF16381.5 EGC39052.1 - 1.2e-25 89.8 0.8 3e-25 88.6 0.8 1.7 1 0 0 1 1 1 1 Coatomer subunit gamma-1 C-terminal appendage platform HEAT_2 PF13646.6 EGC39052.1 - 1.2e-16 60.9 0.3 1.1e-05 25.8 0.0 5.4 5 1 0 5 5 5 2 HEAT repeats Cnd1 PF12717.7 EGC39052.1 - 2.6e-15 56.8 16.2 7.6e-08 32.6 1.9 4.2 3 1 1 4 4 4 3 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.10 EGC39052.1 - 5.9e-05 23.1 1.1 0.00015 21.8 0.6 2.0 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT PF02985.22 EGC39052.1 - 8.6e-05 22.5 5.2 0.87 10.0 0.0 5.6 7 0 0 7 7 6 2 HEAT repeat DNA_alkylation PF08713.11 EGC39052.1 - 0.0035 17.1 0.1 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 DNA alkylation repair enzyme HEAT_EZ PF13513.6 EGC39052.1 - 0.0057 17.1 0.2 28 5.3 0.2 4.6 4 1 0 4 4 4 0 HEAT-like repeat CheZ PF04344.13 EGC39052.1 - 0.0079 16.1 0.2 0.026 14.5 0.1 1.9 1 1 1 2 2 2 1 Chemotaxis phosphatase, CheZ Vac14_Fab1_bd PF12755.7 EGC39052.1 - 1.3 9.7 11.1 28 5.4 0.2 5.3 4 2 2 6 6 6 0 Vacuolar 14 Fab1-binding region Methyltransf_2 PF00891.18 EGC39053.1 - 3.3e-35 121.3 0.0 4.1e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase domain Dimerisation2 PF16864.5 EGC39053.1 - 4.8e-08 32.9 0.1 9.2e-08 32.0 0.1 1.5 1 0 0 1 1 1 1 Dimerisation domain Methyltransf_23 PF13489.6 EGC39053.1 - 0.00039 20.3 0.0 0.00075 19.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ntox27 PF15531.6 EGC39053.1 - 0.0096 15.8 0.0 0.018 14.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial toxin 27 TrmB PF01978.19 EGC39053.1 - 0.072 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PWWP PF00855.17 EGC39054.1 - 8.4e-14 51.8 0.1 8.4e-14 51.8 0.1 3.9 2 1 0 2 2 2 1 PWWP domain FA_desaturase PF00487.24 EGC39055.1 - 2.3e-16 60.4 6.9 2.3e-16 60.4 6.9 3.6 2 1 0 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.28 EGC39055.1 - 2.4e-14 53.2 0.0 6.4e-14 51.8 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Fip1 PF05182.13 EGC39056.1 - 5.8e-24 83.3 2.3 1.1e-23 82.4 2.3 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.12 EGC39056.1 - 2.9e-05 22.9 8.3 2.9e-05 22.9 8.3 2.3 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF3430 PF11912.8 EGC39057.1 - 0.47 10.5 23.3 4.3 7.3 23.3 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) LIM PF00412.22 EGC39058.1 - 1.7e-57 191.5 44.0 3.8e-16 59.1 4.0 4.2 4 0 0 4 4 4 4 LIM domain NTP_transf_2 PF01909.23 EGC39059.1 - 1.1e-08 35.2 0.0 3e-08 33.8 0.0 1.8 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.19 EGC39059.1 - 1e-07 32.0 3.1 2.2e-07 31.0 0.1 3.3 2 1 0 2 2 2 1 Cid1 family poly A polymerase Polbeta PF18765.1 EGC39059.1 - 0.0015 18.6 0.0 0.0057 16.7 0.0 2.0 1 0 0 1 1 1 1 Polymerase beta, Nucleotidyltransferase DapB_C PF05173.14 EGC39059.1 - 0.034 14.2 0.1 0.084 12.9 0.1 1.6 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, C-terminus Macoilin PF09726.9 EGC39062.1 - 0.02 13.5 10.9 0.024 13.2 10.9 1.1 1 0 0 1 1 1 0 Macoilin family Endotoxin_N PF03945.14 EGC39063.1 - 1.5e-05 24.8 0.0 0.0031 17.3 0.0 2.3 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain G-gamma PF00631.22 EGC39064.1 - 2e-17 63.0 0.2 2.1e-17 62.8 0.2 1.0 1 0 0 1 1 1 1 GGL domain RNA_pol_Rpb1_1 PF04997.12 EGC39064.1 - 0.0058 16.0 0.0 0.0066 15.8 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 F_actin_bind PF08919.10 EGC39064.1 - 0.009 16.1 0.1 0.011 15.8 0.1 1.1 1 0 0 1 1 1 1 F-actin binding NEMO PF11577.8 EGC39064.1 - 0.023 14.7 0.5 0.026 14.5 0.5 1.1 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO G_path_suppress PF15991.5 EGC39064.1 - 0.029 14.5 0.0 0.029 14.5 0.0 1.0 1 0 0 1 1 1 0 G-protein pathway suppressor Mto2_bdg PF12808.7 EGC39064.1 - 0.1 12.9 0.9 0.14 12.5 0.9 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region MeMO_Hyd_G PF02964.16 EGC39064.1 - 0.1 12.6 0.0 0.12 12.4 0.0 1.0 1 0 0 1 1 1 0 Methane monooxygenase, hydrolase gamma chain Rad9 PF04139.13 EGC39065.1 - 3.5e-73 246.1 3.5 3.5e-73 246.1 3.5 2.0 2 0 0 2 2 2 1 Rad9 Rad1 PF02144.16 EGC39065.1 - 2.6e-05 23.4 6.2 2.6e-05 23.4 6.2 2.6 2 1 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 NOA36 PF06524.12 EGC39066.1 - 0.4 10.0 12.4 1.1 8.5 5.8 2.2 2 0 0 2 2 2 0 NOA36 protein Secretin_N_2 PF07655.13 EGC39066.1 - 0.96 10.0 19.6 0.13 12.8 13.8 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain Corazonin PF17308.2 EGC39066.1 - 3.8 7.9 21.0 1.7 9.0 10.5 2.9 3 0 0 3 3 3 0 Pro-corazonin Pox_Ag35 PF03286.14 EGC39066.1 - 6.7 6.5 12.8 0.55 10.0 1.2 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein Cofilin_ADF PF00241.20 EGC39067.1 - 1.6e-17 63.4 0.0 1.7e-17 63.3 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Cofilin_ADF PF00241.20 EGC39068.1 - 8.5e-36 122.4 0.0 6.9e-18 64.6 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Phospholip_B PF04916.13 EGC39069.1 - 7.2e-165 549.6 14.2 8.7e-165 549.3 14.2 1.0 1 0 0 1 1 1 1 Phospholipase B API5 PF05918.11 EGC39070.1 - 0.62 8.8 7.3 0.73 8.6 7.3 1.1 1 0 0 1 1 1 0 Apoptosis inhibitory protein 5 (API5) MscL PF01741.18 EGC39071.1 - 0.071 13.4 0.2 0.071 13.4 0.2 2.5 3 0 0 3 3 3 0 Large-conductance mechanosensitive channel, MscL RETICULATA-like PF11891.8 EGC39071.1 - 0.084 12.7 0.1 0.27 11.1 0.0 1.8 1 1 0 1 1 1 0 Protein RETICULATA-related DUF4093 PF13331.6 EGC39073.1 - 0.082 13.4 0.1 0.16 12.4 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4093) Repressor_Mnt PF11423.8 EGC39073.1 - 0.098 12.4 0.0 0.3 10.9 0.0 1.8 1 0 0 1 1 1 0 Regulatory protein Mnt DUF4013 PF13197.6 EGC39073.1 - 9.7 6.0 16.2 0.21 11.4 2.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) ABC_membrane PF00664.23 EGC39074.1 - 4.1e-68 230.0 36.6 4e-39 134.9 16.2 2.7 2 1 1 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.27 EGC39074.1 - 2.3e-52 177.1 0.3 1.2e-30 106.8 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.19 EGC39074.1 - 2e-12 47.0 4.5 0.012 15.1 0.0 4.3 2 2 2 4 4 4 4 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.23 EGC39074.1 - 9.9e-07 28.8 1.0 0.025 14.6 0.0 3.3 3 0 0 3 3 3 2 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC39074.1 - 2.6e-06 27.4 0.1 0.00027 20.9 0.0 2.5 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC39074.1 - 4e-05 23.3 6.2 0.0074 16.0 0.1 3.0 3 0 0 3 3 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.23 EGC39074.1 - 0.00014 21.9 3.2 0.0033 17.5 0.4 2.9 2 0 0 2 2 2 1 Dynamin family AAA_23 PF13476.6 EGC39074.1 - 0.00018 22.0 6.4 0.013 16.0 0.0 3.9 4 0 0 4 4 3 1 AAA domain Zeta_toxin PF06414.12 EGC39074.1 - 0.00028 20.3 0.0 0.099 11.9 0.0 2.4 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 EGC39074.1 - 0.00034 19.8 0.0 0.19 10.7 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein TrwB_AAD_bind PF10412.9 EGC39074.1 - 0.00049 19.1 0.2 0.22 10.4 0.0 2.3 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_16 PF13191.6 EGC39074.1 - 0.00094 19.6 0.0 2 8.8 0.0 2.9 3 0 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.6 EGC39074.1 - 0.0029 17.9 0.2 1.6 9.0 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_7 PF12775.7 EGC39074.1 - 0.0062 16.1 0.2 2.2 7.8 0.0 2.7 2 0 0 2 2 2 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGC39074.1 - 0.012 15.0 0.7 2 7.7 0.1 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_21 PF13304.6 EGC39074.1 - 0.012 15.4 2.4 1.6 8.5 0.1 3.9 3 1 1 4 4 4 0 AAA domain, putative AbiEii toxin, Type IV TA system AAA_27 PF13514.6 EGC39074.1 - 0.022 14.3 0.2 0.15 11.7 0.0 2.1 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.17 EGC39074.1 - 0.026 14.6 0.2 0.026 14.6 0.2 3.2 4 0 0 4 4 3 0 Helicase HerA, central domain AAA_30 PF13604.6 EGC39074.1 - 0.047 13.4 0.1 16 5.1 0.0 2.6 3 0 0 3 3 3 0 AAA domain DUF815 PF05673.13 EGC39074.1 - 0.047 12.8 0.1 6 6.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Roc PF08477.13 EGC39074.1 - 0.055 13.7 1.3 33 4.7 0.0 3.5 3 0 0 3 3 3 0 Ras of Complex, Roc, domain of DAPkinase Ploopntkinase3 PF18751.1 EGC39074.1 - 0.075 12.9 0.2 7.5 6.4 0.0 2.3 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 IstB_IS21 PF01695.17 EGC39074.1 - 0.086 12.6 0.8 4.9 6.8 0.0 3.5 4 0 0 4 4 4 0 IstB-like ATP binding protein RNA_helicase PF00910.22 EGC39074.1 - 0.089 13.2 0.1 33 4.9 0.0 3.1 3 0 0 3 3 2 0 RNA helicase AAA_10 PF12846.7 EGC39074.1 - 0.089 11.7 0.4 6.4 5.6 0.0 2.3 2 0 0 2 2 2 0 AAA-like domain ATP_bind_1 PF03029.17 EGC39074.1 - 0.099 12.4 0.2 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein cobW PF02492.19 EGC39074.1 - 0.1 12.1 1.1 0.41 10.2 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AIG1 PF04548.16 EGC39074.1 - 0.14 11.4 1.4 4 6.7 0.1 2.5 2 0 0 2 2 2 0 AIG1 family AAA_33 PF13671.6 EGC39074.1 - 0.21 11.7 0.0 7.1 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF3987 PF13148.6 EGC39074.1 - 0.25 10.3 0.0 17 4.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3987) Piwi PF02171.17 EGC39075.1 - 7.2e-58 196.2 8.3 7.2e-58 196.2 8.3 2.2 2 0 0 2 2 2 1 Piwi domain PCI PF01399.27 EGC39076.1 - 2.8e-25 88.8 9.6 4.6e-25 88.1 2.2 3.2 3 0 0 3 3 3 1 PCI domain DpnI_C PF17726.1 EGC39076.1 - 0.53 10.4 4.3 1.4 9.1 0.4 2.8 2 0 0 2 2 2 0 Dam-replacing HTH domain TPR_11 PF13414.6 EGC39076.1 - 0.66 9.7 3.8 4.2 7.1 0.0 3.6 4 0 0 4 4 4 0 TPR repeat TPR_8 PF13181.6 EGC39076.1 - 0.88 9.9 6.5 31 5.1 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39076.1 - 6.2 7.2 5.9 79 3.7 0.0 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat FNIP PF05725.12 EGC39078.1 - 8.3e-102 333.2 88.0 1.2e-13 51.0 1.3 13.4 11 3 3 14 14 14 13 FNIP Repeat IL2 PF00715.17 EGC39078.1 - 0.1 12.5 0.2 0.32 10.9 0.0 1.8 2 0 0 2 2 2 0 Interleukin 2 ORMDL PF04061.14 EGC39079.1 - 3.5e-47 159.6 4.7 3.9e-47 159.5 4.7 1.0 1 0 0 1 1 1 1 ORMDL family ERO1 PF04137.15 EGC39080.1 - 9.4e-112 373.7 1.8 9.4e-112 373.7 1.8 1.5 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) EMC3_TMCO1 PF01956.16 EGC39080.1 - 0.11 12.2 1.6 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Integral membrane protein EMC3/TMCO1-like FH2 PF02181.23 EGC39081.1 - 9.4e-83 278.4 18.4 9.4e-83 278.4 18.4 3.2 4 1 0 4 4 4 1 Formin Homology 2 Domain Drf_FH3 PF06367.16 EGC39081.1 - 1.2e-37 129.4 2.6 1.2e-37 129.4 2.6 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.13 EGC39081.1 - 1.4e-18 67.1 0.1 1.4e-18 67.1 0.1 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain IDO PF01231.18 EGC39081.1 - 0.012 14.5 0.1 0.012 14.5 0.1 2.6 3 0 0 3 3 3 0 Indoleamine 2,3-dioxygenase DUF3361 PF11841.8 EGC39081.1 - 0.36 10.7 7.9 0.16 11.9 1.6 3.5 4 1 0 4 4 4 0 Domain of unknown function (DUF3361) DER1 PF04511.15 EGC39082.1 - 1.1e-45 155.9 14.2 1.3e-45 155.7 14.2 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_L21p PF00829.21 EGC39083.1 - 3.4e-30 104.3 2.9 4.4e-30 103.9 2.9 1.1 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Patatin PF01734.22 EGC39084.1 - 4.1e-27 95.7 0.0 7.3e-27 94.9 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase TMEM132D_C PF15706.5 EGC39085.1 - 2.1 8.2 0.0 2.1 8.2 0.0 4.4 6 1 0 6 6 6 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term CENP-T_C PF15511.6 EGC39086.1 - 2.1e-08 34.2 0.1 2.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC39086.1 - 0.00027 21.3 0.0 0.00076 19.8 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein TAF PF02969.17 EGC39086.1 - 0.00033 20.8 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ribosomal_L29e PF01779.17 EGC39086.1 - 0.0024 18.1 1.6 0.0094 16.3 1.6 1.9 1 1 0 1 1 1 1 Ribosomal L29e protein family CBFD_NFYB_HMF PF00808.23 EGC39086.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGC39086.1 - 0.0077 16.2 0.1 0.013 15.5 0.1 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGC39086.1 - 0.0079 16.3 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGC39086.1 - 0.017 15.5 0.7 0.028 14.8 0.7 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EGC39086.1 - 0.033 14.2 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CRT-like PF08627.10 EGC39087.1 - 6.3e-46 156.9 6.0 7.6e-46 156.6 6.0 1.1 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like zf-CCCH PF00642.24 EGC39088.1 - 1.2e-20 72.9 13.1 9.1e-12 44.6 2.2 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGC39088.1 - 7.7e-12 44.7 9.5 1.2e-05 24.9 0.7 2.3 2 0 0 2 2 2 2 CCCH-type zinc finger zf_CCCH_4 PF18345.1 EGC39088.1 - 3.2e-10 39.7 12.0 2.2e-05 24.3 2.7 2.3 2 0 0 2 2 2 2 Zinc finger domain zf-CCCH_2 PF14608.6 EGC39088.1 - 7.4e-05 23.1 6.0 0.024 15.1 0.2 2.5 2 0 0 2 2 2 2 RNA-binding, Nab2-type zinc finger SprA-related PF12118.8 EGC39088.1 - 0.48 9.5 35.6 0.56 9.3 17.4 2.2 2 0 0 2 2 2 0 SprA-related family SpoIIP PF07454.11 EGC39088.1 - 0.9 8.9 19.4 0.16 11.4 13.3 2.1 2 0 0 2 2 2 0 Stage II sporulation protein P (SpoIIP) DUF2052 PF09747.9 EGC39088.1 - 1.1 9.3 18.2 0.33 11.1 12.3 2.1 2 0 0 2 2 2 0 Coiled-coil domain containing protein (DUF2052) NARP1 PF12569.8 EGC39088.1 - 1.3 7.8 12.7 2.4 6.9 12.7 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Connexin PF00029.19 EGC39088.1 - 1.4 8.6 15.0 5.4 6.7 10.2 2.1 2 0 0 2 2 2 0 Connexin zf-CCHH PF10283.9 EGC39088.1 - 1.6 8.8 6.5 3.1 7.9 1.2 2.8 2 0 0 2 2 2 0 PBZ domain Bud13 PF09736.9 EGC39088.1 - 1.8 9.0 18.1 10 6.5 13.1 2.3 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex TFIIA PF03153.13 EGC39088.1 - 3.2 7.7 59.4 0.2 11.6 36.9 2.1 1 1 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit TERB2 PF15101.6 EGC39088.1 - 6.2 6.8 20.1 1.2 9.2 12.4 2.5 2 0 0 2 2 2 0 Telomere-associated protein TERB2 DUF3675 PF12428.8 EGC39088.1 - 6.7 7.3 5.4 4.5 7.8 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) Eapp_C PF10238.9 EGC39088.1 - 7.1 6.7 15.3 0.74 9.9 8.0 2.3 2 0 0 2 2 2 0 E2F-associated phosphoprotein Tim54 PF11711.8 EGC39088.1 - 9.9 4.8 20.5 1.5 7.5 15.7 2.0 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 RCC1 PF00415.18 EGC39089.1 - 7.9e-66 218.5 15.9 4.3e-11 43.2 0.1 8.3 8 1 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC39089.1 - 1e-34 117.6 33.9 8.5e-08 31.8 0.5 8.3 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat FtsJ PF01728.19 EGC39090.1 - 2.4e-05 24.5 0.0 4.6e-05 23.6 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Inhibitor_I29 PF08246.12 EGC39091.1 - 1.3e-16 60.8 0.4 4.5e-16 59.0 0.4 1.9 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Mersacidin PF16934.5 EGC39091.1 - 0.1 12.4 2.6 0.2 11.4 2.6 1.5 1 1 0 1 1 1 0 Two-component Enterococcus faecalis cytolysin (EFC) MccV PF17508.2 EGC39091.1 - 0.11 13.1 2.7 0.17 12.5 2.7 1.3 1 0 0 1 1 1 0 Microcin V bacteriocin Tic110 PF16940.5 EGC39091.1 - 0.68 8.3 3.6 0.88 8.0 3.6 1.1 1 0 0 1 1 1 0 Chloroplast envelope transporter Glycos_transf_1 PF00534.20 EGC39092.1 - 2.9e-12 46.5 0.0 5e-11 42.4 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC39092.1 - 2.4e-08 34.5 0.0 2.6e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC39092.1 - 0.0038 17.3 0.0 0.0059 16.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.6 EGC39092.1 - 0.0057 17.1 0.0 0.0079 16.6 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Acyl_transf_1 PF00698.21 EGC39095.1 - 1.1e-37 130.3 0.0 1.3e-37 130.1 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DnaJ PF00226.31 EGC39096.1 - 3.6e-22 78.3 3.2 8.1e-22 77.1 3.2 1.7 1 0 0 1 1 1 1 DnaJ domain DnaJ_C PF01556.18 EGC39096.1 - 2.1e-17 63.6 0.0 3.4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.19 EGC39096.1 - 0.026 14.9 5.1 0.026 14.9 5.1 2.1 1 1 1 2 2 2 0 DnaJ central domain Macoilin PF09726.9 EGC39096.1 - 4.2 5.8 20.3 0.15 10.6 9.5 2.2 2 0 0 2 2 2 0 Macoilin family zf-RING_2 PF13639.6 EGC39097.1 - 7.1e-11 42.3 11.0 1.2e-10 41.6 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39097.1 - 1.8e-08 34.1 7.2 2.8e-08 33.5 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39097.1 - 3.1e-08 33.3 11.8 5.3e-08 32.6 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39097.1 - 2.9e-07 30.2 12.0 5.6e-07 29.3 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39097.1 - 3e-07 30.6 9.1 8.2e-07 29.2 9.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC39097.1 - 5.2e-05 23.0 6.0 0.0001 22.1 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC39097.1 - 0.00048 20.0 9.4 0.00087 19.2 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39097.1 - 0.0017 18.3 5.5 0.004 17.2 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC39097.1 - 0.0088 15.8 10.6 0.016 15.0 10.6 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain IBR PF01485.21 EGC39097.1 - 0.016 15.4 8.8 0.048 13.9 8.8 1.9 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EGC39097.1 - 0.022 14.9 9.4 0.042 14.0 8.3 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC39097.1 - 0.052 13.3 6.2 0.12 12.2 6.2 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC39097.1 - 0.069 13.2 4.1 0.15 12.2 4.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC39097.1 - 0.071 13.3 4.7 0.15 12.2 4.7 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EGC39097.1 - 0.16 12.1 7.2 0.29 11.2 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC39097.1 - 0.86 9.3 7.9 1.4 8.6 7.9 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 EGC39097.1 - 6.1 7.2 14.6 2.5 8.4 10.2 2.6 1 1 1 2 2 2 0 PHD-like zinc-binding domain V_ATPase_I PF01496.19 EGC39097.1 - 9.2 4.0 25.7 0.26 9.1 2.2 2.3 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family zf-RING_2 PF13639.6 EGC39098.1 - 8.2e-11 42.1 11.0 1.3e-10 41.4 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39098.1 - 2.1e-08 33.9 7.2 3.2e-08 33.3 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39098.1 - 3.7e-08 33.1 11.8 6.1e-08 32.4 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39098.1 - 3.5e-07 30.0 12.0 6.5e-07 29.1 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39098.1 - 9e-07 29.1 9.4 9e-07 29.1 9.4 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC39098.1 - 6e-05 22.8 6.0 0.00012 21.9 6.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC39098.1 - 0.00057 19.8 9.4 0.001 19.0 9.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39098.1 - 0.002 18.1 5.5 0.0046 17.0 5.5 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC39098.1 - 0.01 15.6 10.6 0.019 14.8 10.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.6 EGC39098.1 - 0.017 15.3 8.5 0.03 14.5 7.7 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING IBR PF01485.21 EGC39098.1 - 0.024 14.8 9.5 0.068 13.4 9.5 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain DUF4834 PF16118.5 EGC39098.1 - 0.03 15.3 1.0 0.03 15.3 1.0 6.4 1 1 1 2 2 1 0 Domain of unknown function (DUF4834) zf-ANAPC11 PF12861.7 EGC39098.1 - 0.06 13.4 4.1 0.13 12.3 4.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC39098.1 - 0.067 12.9 6.2 0.13 12.0 6.2 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EGC39098.1 - 0.076 13.2 4.6 0.15 12.2 4.6 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF1272 PF06906.11 EGC39098.1 - 0.17 12.0 7.0 0.33 11.1 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-HC5HC2H PF13771.6 EGC39098.1 - 0.57 10.5 12.5 1 9.7 10.9 2.3 1 1 0 1 1 1 0 PHD-like zinc-binding domain Zn_ribbon_17 PF17120.5 EGC39098.1 - 1.1 9.0 8.2 1.7 8.3 8.2 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type MFAP1 PF06991.11 EGC39098.1 - 3.3 7.5 36.6 0.017 15.0 20.7 3.0 3 0 0 3 3 3 0 Microfibril-associated/Pre-mRNA processing LRR_6 PF13516.6 EGC39099.1 - 8e-06 25.5 12.7 0.29 11.3 0.3 6.3 7 0 0 7 7 7 3 Leucine Rich repeat F-box-like PF12937.7 EGC39099.1 - 0.0024 17.7 0.2 0.0052 16.7 0.2 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC39099.1 - 0.0058 16.5 0.7 0.017 15.0 0.7 1.8 1 0 0 1 1 1 1 F-box domain LRR_8 PF13855.6 EGC39099.1 - 0.02 14.6 2.6 0.02 14.6 2.6 4.5 5 2 0 5 5 5 0 Leucine rich repeat LRR_1 PF00560.33 EGC39099.1 - 0.49 11.1 13.1 17 6.5 0.1 6.5 5 1 0 5 5 5 0 Leucine Rich Repeat LRR_4 PF12799.7 EGC39099.1 - 2.8 8.5 23.5 0.79 10.2 0.2 5.4 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) Branch PF02485.21 EGC39100.1 - 3e-17 63.0 4.0 7.3e-17 61.7 4.0 1.6 1 1 0 1 1 1 1 Core-2/I-Branching enzyme EGF_2 PF07974.13 EGC39100.1 - 0.21 12.0 4.4 0.44 11.0 4.4 1.5 1 0 0 1 1 1 0 EGF-like domain GLE1 PF07817.13 EGC39101.1 - 2.8e-50 170.9 1.8 2.8e-50 170.9 1.8 2.8 3 0 0 3 3 3 1 GLE1-like protein SipA_VBS PF17985.1 EGC39102.1 - 2.1 8.4 4.9 4.8 7.3 1.2 3.0 2 0 0 2 2 2 0 SipA vinculin binding site adh_short PF00106.25 EGC39103.1 - 2.2e-42 144.7 0.0 3.1e-42 144.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC39103.1 - 2.7e-28 99.1 0.0 3.4e-28 98.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC39103.1 - 4.4e-07 30.0 0.0 7.3e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC39103.1 - 0.0013 18.1 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Polysacc_synt_2 PF02719.15 EGC39103.1 - 0.028 13.5 0.0 0.043 12.9 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein LBP_C PF17386.2 EGC39103.1 - 0.077 12.9 0.0 0.17 11.8 0.0 1.5 1 0 0 1 1 1 0 Lacto-N-biose phosphorylase C-terminal domain Epimerase PF01370.21 EGC39103.1 - 0.14 11.6 0.0 0.28 10.6 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF4334 PF14232.6 EGC39104.1 - 0.046 13.7 0.0 0.088 12.8 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) AAA_7 PF12775.7 EGC39105.1 - 0.00012 21.7 8.0 0.079 12.5 0.3 5.0 5 0 0 5 5 5 2 P-loop containing dynein motor region AAA PF00004.29 EGC39105.1 - 0.0024 18.3 1.1 0.29 11.5 0.0 4.1 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.14 EGC39105.1 - 0.0049 16.9 0.7 4.1 7.4 0.0 4.6 6 0 0 6 6 6 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC39105.1 - 0.059 13.7 0.0 0.79 10.1 0.0 3.0 2 1 0 2 2 2 0 AAA ATPase domain zf-RING_2 PF13639.6 EGC39106.1 - 0.00021 21.6 11.4 0.00021 21.6 11.4 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGC39106.1 - 0.00034 20.4 13.1 0.0015 18.3 13.1 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39106.1 - 0.0013 18.5 11.5 0.0013 18.5 11.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC39106.1 - 0.0014 18.5 13.1 0.0014 18.5 13.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC39106.1 - 0.0018 18.4 6.3 0.0063 16.6 6.3 2.0 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGC39106.1 - 0.0083 16.1 8.9 0.03 14.4 8.9 2.0 1 0 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC39106.1 - 0.013 15.3 13.4 0.013 15.3 13.4 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC39106.1 - 0.019 15.2 8.5 0.019 15.2 8.5 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC39106.1 - 0.078 12.9 4.1 0.16 11.9 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.6 EGC39106.1 - 4.3 7.2 12.6 0.39 10.5 6.0 2.6 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Romo1 PF10247.9 EGC39107.1 - 2.4e-19 69.5 11.4 2.6e-19 69.3 11.4 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Tim17 PF02466.19 EGC39107.1 - 0.0066 16.8 3.4 0.0071 16.7 3.4 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family ABC_membrane PF00664.23 EGC39108.1 - 3.1e-49 168.1 26.6 6.1e-49 167.1 26.6 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 EGC39108.1 - 2.2e-45 155.2 5.1 2.2e-45 155.2 5.1 1.8 2 0 0 2 2 1 1 Subtilase family ABC_tran PF00005.27 EGC39108.1 - 2.5e-32 112.3 0.0 8.8e-32 110.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGC39108.1 - 2.3e-10 40.3 0.0 1.7e-09 37.4 0.0 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGC39108.1 - 1.3e-05 25.1 10.6 0.0087 15.9 0.1 3.5 2 1 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_29 PF13555.6 EGC39108.1 - 0.0083 15.8 0.0 0.024 14.4 0.0 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.6 EGC39108.1 - 0.0085 16.4 0.0 0.031 14.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC39108.1 - 0.013 15.4 0.0 0.22 11.4 0.0 2.7 2 0 0 2 2 2 0 RsgA GTPase ECR1_N PF14382.6 EGC39108.1 - 0.014 15.2 0.0 0.34 10.7 0.1 2.7 2 0 0 2 2 2 0 Exosome complex exonuclease RRP4 N-terminal region NTPase_1 PF03266.15 EGC39108.1 - 0.15 12.0 0.3 0.53 10.2 0.0 2.0 2 0 0 2 2 2 0 NTPase AAA_16 PF13191.6 EGC39108.1 - 0.17 12.3 0.0 0.38 11.1 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_membrane PF00664.23 EGC39109.1 - 7.1e-51 173.5 27.6 7.1e-51 173.5 27.6 1.6 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.22 EGC39109.1 - 8.2e-49 166.5 1.4 8.2e-49 166.5 1.4 2.9 3 0 0 3 3 3 1 Subtilase family ABC_tran PF00005.27 EGC39109.1 - 5.2e-31 108.0 0.0 5.2e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.19 EGC39109.1 - 7.4e-07 28.8 2.9 7.4e-07 28.8 2.9 2.7 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.6 EGC39109.1 - 0.0011 18.9 8.8 0.13 12.0 0.0 3.5 3 0 0 3 3 3 2 AAA domain, putative AbiEii toxin, Type IV TA system ECR1_N PF14382.6 EGC39109.1 - 0.0071 16.1 0.0 0.15 11.9 0.1 2.4 2 0 0 2 2 2 1 Exosome complex exonuclease RRP4 N-terminal region AAA_22 PF13401.6 EGC39109.1 - 0.03 14.6 0.0 0.099 12.9 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC39109.1 - 0.13 12.0 0.0 0.3 10.8 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC39109.1 - 3.2 8.3 0.0 3.2 8.3 0.0 3.2 2 0 0 2 2 2 0 AAA domain LRR_6 PF13516.6 EGC39110.1 - 4.9e-17 60.5 1.1 0.00075 19.4 0.0 4.5 4 0 0 4 4 4 3 Leucine Rich repeat F-box-like PF12937.7 EGC39110.1 - 6.4e-06 26.0 0.1 1.1e-05 25.3 0.1 1.4 1 0 0 1 1 1 1 F-box-like DASH_Dad4 PF08650.10 EGC39110.1 - 0.027 14.4 2.0 0.068 13.2 0.7 2.4 2 0 0 2 2 2 0 DASH complex subunit Dad4 F-box PF00646.33 EGC39110.1 - 0.056 13.3 0.0 0.35 10.8 0.0 2.1 2 0 0 2 2 2 0 F-box domain LRR_4 PF12799.7 EGC39110.1 - 0.078 13.4 6.9 1.2 9.6 0.7 4.5 4 1 1 5 5 5 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC39110.1 - 0.093 12.5 8.1 9.5 6.1 0.1 4.6 4 1 1 5 5 5 0 Leucine rich repeat DHHC PF01529.20 EGC39111.1 - 5.7 7.1 9.0 0.48 10.5 0.3 2.5 2 1 0 2 2 2 0 DHHC palmitoyltransferase Peptidase_C1 PF00112.23 EGC39112.1 - 1.7e-54 185.2 6.3 1.7e-54 185.2 6.3 2.0 2 1 0 2 2 2 1 Papain family cysteine protease CAP PF00188.26 EGC39112.1 - 7.1e-08 33.3 6.8 7.1e-08 33.3 6.8 2.6 2 1 0 2 2 2 1 Cysteine-rich secretory protein family Peptidase_C39_2 PF13529.6 EGC39112.1 - 0.016 15.7 0.3 0.016 15.7 0.3 2.4 3 1 0 3 3 3 0 Peptidase_C39 like family Meiosis_expr PF15163.6 EGC39112.1 - 0.075 13.7 0.1 0.3 11.8 0.1 2.0 1 0 0 1 1 1 0 Meiosis-expressed EF1_GNE PF00736.19 EGC39113.1 - 1.5e-21 76.4 2.9 1.6e-21 76.2 2.9 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain DUF4363 PF14276.6 EGC39113.1 - 0.044 13.9 0.3 0.14 12.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) Tnp_22_trimer PF17489.2 EGC39113.1 - 0.11 12.5 1.6 0.11 12.5 1.6 1.9 2 0 0 2 2 2 0 L1 transposable element trimerization domain MMS1_N PF10433.9 EGC39114.1 - 2.6e-103 346.3 1.6 5.7e-103 345.2 0.3 2.2 2 1 0 3 3 3 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGC39114.1 - 4.1e-59 200.5 0.0 1.9e-58 198.3 0.0 2.1 2 0 0 2 2 2 1 CPSF A subunit region TruB_C PF09142.11 EGC39114.1 - 0.014 15.2 0.0 0.035 13.9 0.0 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Pkinase PF00069.25 EGC39115.1 - 4.6e-64 216.3 0.0 4.6e-64 216.3 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39115.1 - 1.2e-42 146.0 0.0 2.2e-42 145.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ephrin_rec_like PF07699.13 EGC39115.1 - 1.2e-10 40.9 66.0 5e-06 26.2 7.2 7.5 2 1 7 9 9 9 7 Putative ephrin-receptor like Kinase-like PF14531.6 EGC39115.1 - 0.00011 21.7 0.0 0.0002 20.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC39115.1 - 0.00051 20.0 0.0 0.0015 18.5 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.14 EGC39115.1 - 0.0036 16.7 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family OAD_gamma PF04277.13 EGC39115.1 - 1.2 9.7 4.1 4.3 8.0 4.1 2.0 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain NCD3G PF07562.14 EGC39115.1 - 2 8.4 49.1 0.18 11.8 1.8 6.4 4 2 3 7 7 7 0 Nine Cysteines Domain of family 3 GPCR Ribosomal_L37e PF01907.19 EGC39115.1 - 3.4 7.9 15.1 0.28 11.4 0.6 3.5 3 0 0 3 3 3 0 Ribosomal protein L37e DPBB_1 PF03330.18 EGC39116.1 - 1.6e-10 41.1 0.7 1.9e-09 37.6 0.7 2.6 1 1 0 1 1 1 1 Lytic transglycolase Pollen_allerg_1 PF01357.21 EGC39116.1 - 5.3e-05 23.2 0.1 0.00011 22.1 0.1 1.5 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.17 EGC39116.1 - 0.00012 21.9 0.6 0.00022 21.1 0.6 1.4 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.12 EGC39116.1 - 0.00087 19.4 1.4 0.0019 18.3 1.0 1.8 1 1 0 1 1 1 1 Cerato-platanin Sel1 PF08238.12 EGC39117.1 - 8.7e-30 102.5 10.8 2.9e-06 27.7 0.6 6.1 6 0 0 6 6 6 6 Sel1 repeat TPR_7 PF13176.6 EGC39117.1 - 0.02 14.9 0.2 14 6.0 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39117.1 - 0.04 14.1 1.9 23 5.5 0.0 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39117.1 - 0.19 11.9 10.9 40 4.7 2.2 5.7 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39117.1 - 1.9 8.5 14.9 9.8 6.2 0.2 5.7 7 0 0 7 7 7 0 Tetratricopeptide repeat ETRAMP PF09716.10 EGC39118.1 - 0.0071 16.4 0.8 0.039 14.0 0.8 2.3 1 0 0 1 1 1 1 Malarial early transcribed membrane protein (ETRAMP) EGF_2 PF07974.13 EGC39118.1 - 0.67 10.4 11.4 1.6 9.1 11.4 1.6 1 0 0 1 1 1 0 EGF-like domain NUDIX PF00293.28 EGC39119.1 - 5.9e-05 23.1 0.0 0.00014 21.9 0.0 1.7 1 1 0 1 1 1 1 NUDIX domain Presenilin PF01080.17 EGC39119.1 - 5.8 5.6 13.3 7.6 5.2 13.3 1.4 1 0 0 1 1 1 0 Presenilin Ank_2 PF12796.7 EGC39120.1 - 0.00023 21.7 0.5 0.0043 17.6 0.1 3.3 4 0 0 4 4 4 1 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC39120.1 - 0.88 10.3 4.1 67 4.5 0.0 5.3 6 0 0 6 6 6 0 Ankyrin repeat Cnd1 PF12717.7 EGC39120.1 - 0.89 9.6 8.7 0.54 10.3 1.9 3.4 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 F5_F8_type_C PF00754.25 EGC39121.1 - 4.1e-25 88.4 2.0 4.6e-25 88.2 0.8 1.7 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC39121.1 - 2.1e-21 75.9 0.4 5.6e-21 74.5 0.4 1.8 1 0 0 1 1 1 1 H-type lectin domain F5_F8_type_C PF00754.25 EGC39122.1 - 4.2e-22 78.6 1.0 5.9e-22 78.1 0.3 1.6 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC39122.1 - 9.7e-21 73.7 0.5 3e-20 72.2 0.5 1.9 1 0 0 1 1 1 1 H-type lectin domain ubiquitin PF00240.23 EGC39123.1 - 0.00018 21.2 0.0 0.0005 19.8 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.6 EGC39123.1 - 0.019 15.4 0.0 0.044 14.2 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain zf-RING_2 PF13639.6 EGC39124.1 - 7.4e-11 42.2 11.0 1.4e-10 41.4 11.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39124.1 - 1.7e-08 34.2 7.2 3.3e-08 33.3 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39124.1 - 6.2e-08 32.4 11.8 6.2e-08 32.4 11.8 1.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39124.1 - 1.8e-07 31.3 8.9 9e-07 29.1 8.9 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC39124.1 - 6.6e-07 29.1 12.0 6.6e-07 29.1 12.0 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC39124.1 - 5.6e-05 22.9 6.0 0.00012 21.8 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC39124.1 - 0.00045 20.1 9.4 0.001 19.0 9.4 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39124.1 - 0.0013 18.7 5.5 0.0047 16.9 5.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC39124.1 - 0.0099 15.7 10.6 0.019 14.7 10.6 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain IBR PF01485.21 EGC39124.1 - 0.013 15.7 8.5 0.051 13.8 8.5 2.1 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EGC39124.1 - 0.018 15.2 9.1 0.042 14.0 8.1 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC39124.1 - 0.057 13.2 6.2 0.14 12.0 6.2 1.7 1 0 0 1 1 1 0 RING-like zinc finger zf-ANAPC11 PF12861.7 EGC39124.1 - 0.061 13.4 4.1 0.17 11.9 4.1 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.11 EGC39124.1 - 0.14 12.2 7.0 0.29 11.2 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC39124.1 - 0.9 9.2 7.9 1.6 8.4 7.9 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-RING_10 PF16685.5 EGC39124.1 - 4.1 7.6 10.6 0.2 11.8 4.7 1.9 2 0 0 2 2 1 0 zinc RING finger of MSL2 HTH_9 PF08221.11 EGC39126.1 - 9.2e-17 60.9 0.8 9.9e-10 38.4 0.1 3.4 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.13 EGC39126.1 - 0.00013 21.8 7.6 0.004 17.0 4.4 2.8 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 EF-hand_9 PF14658.6 EGC39126.1 - 0.00095 19.4 0.1 0.01 16.1 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain TFIIE_alpha PF02002.17 EGC39126.1 - 0.0015 18.4 5.2 0.014 15.3 0.0 3.9 4 1 1 5 5 5 1 TFIIE alpha subunit Iso_dh PF00180.20 EGC39127.1 - 2.2e-74 250.7 0.0 2.5e-74 250.5 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Phe_ZIP PF08916.11 EGC39127.1 - 0.024 15.3 0.9 0.41 11.4 0.1 2.6 2 0 0 2 2 2 0 Phenylalanine zipper Ras PF00071.22 EGC39128.1 - 4.7e-58 195.4 0.5 6.5e-58 194.9 0.5 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39128.1 - 1.2e-36 125.6 0.2 1.8e-36 125.0 0.2 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39128.1 - 7.3e-14 51.6 0.3 8.8e-14 51.3 0.3 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC39128.1 - 5e-06 26.2 0.2 3.5e-05 23.4 0.2 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGC39128.1 - 2.3e-05 23.9 0.1 4e-05 23.1 0.1 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.23 EGC39128.1 - 7.6e-05 22.8 0.1 0.00012 22.1 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.12 EGC39128.1 - 9.3e-05 21.9 0.2 0.00011 21.6 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC39128.1 - 0.00043 20.2 0.1 0.073 13.0 0.0 2.2 2 0 0 2 2 2 2 RsgA GTPase Ribonuc_L-PSP PF01042.21 EGC39129.1 - 1.8e-40 137.7 0.1 2e-40 137.6 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP VRR_NUC PF08774.11 EGC39130.1 - 2.8e-24 85.3 0.1 7.6e-24 83.9 0.1 1.8 1 0 0 1 1 1 1 VRR-NUC domain DNA_pol_phi PF04931.13 EGC39131.1 - 0.066 11.3 15.7 0.1 10.7 15.7 1.3 1 0 0 1 1 1 0 DNA polymerase phi ZZ PF00569.17 EGC39132.1 - 8.9e-11 41.4 4.1 1.5e-10 40.7 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.31 EGC39132.1 - 6.1e-10 39.1 0.3 1.3e-09 38.1 0.3 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC39132.1 - 0.0036 17.5 0.2 0.033 14.4 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain zinc-ribbons_6 PF07191.12 EGC39132.1 - 0.041 13.9 2.5 0.08 12.9 2.5 1.4 1 0 0 1 1 1 0 zinc-ribbons PSCyt3 PF07627.11 EGC39132.1 - 2.3 8.6 4.4 10 6.5 4.4 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1588) ABC2_membrane PF01061.24 EGC39133.1 - 1.2e-33 116.3 32.4 1.5e-28 99.7 18.0 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.27 EGC39133.1 - 1e-22 81.2 0.0 5.4e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.11 EGC39133.1 - 9.8e-05 22.0 4.2 0.00037 20.2 0.1 2.7 2 0 0 2 2 2 1 Plant PDR ABC transporter associated Rad17 PF03215.15 EGC39133.1 - 0.00048 20.1 0.0 0.0013 18.7 0.0 1.7 1 0 0 1 1 1 1 Rad17 P-loop domain AAA_18 PF13238.6 EGC39133.1 - 0.0041 17.7 0.0 0.01 16.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain DUF1761 PF08570.10 EGC39133.1 - 0.0097 16.2 2.8 0.44 10.8 0.1 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF1761) AAA_22 PF13401.6 EGC39133.1 - 0.039 14.2 0.0 0.096 13.0 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC39133.1 - 0.042 14.1 0.0 0.073 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.14 EGC39133.1 - 0.056 13.4 0.0 0.13 12.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_16 PF13191.6 EGC39133.1 - 0.079 13.3 0.0 0.15 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGC39133.1 - 0.081 13.3 0.1 0.25 11.8 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AgrB PF04647.15 EGC39133.1 - 0.11 11.8 17.7 0.1 11.9 12.1 2.8 2 0 0 2 2 2 0 Accessory gene regulator B IstB_IS21 PF01695.17 EGC39133.1 - 0.2 11.4 0.0 0.41 10.4 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_21 PF13304.6 EGC39133.1 - 0.25 11.1 0.0 0.25 11.1 0.0 3.9 5 0 0 5 5 5 0 AAA domain, putative AbiEii toxin, Type IV TA system PDR_CDR PF06422.12 EGC39133.1 - 0.42 10.5 2.3 1.2 9.1 0.0 2.6 2 0 0 2 2 2 0 CDR ABC transporter TMEM208_SND2 PF05620.11 EGC39133.1 - 5.4 6.8 5.5 4.5 7.0 0.2 2.7 2 0 0 2 2 2 0 SRP-independent targeting protein 2/TMEM208 UCR_14kD PF02271.16 EGC39134.1 - 2.6e-18 65.9 0.5 3e-18 65.6 0.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Cyclin_N PF00134.23 EGC39135.1 - 1.3e-25 89.6 0.5 2.8e-25 88.5 0.5 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.19 EGC39135.1 - 0.00056 20.0 0.2 0.0014 18.7 0.2 1.7 1 0 0 1 1 1 1 Cyclin, C-terminal domain DPM3 PF08285.11 EGC39136.1 - 5.4e-31 106.6 0.3 6e-31 106.5 0.3 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RICTOR_N PF14664.6 EGC39137.1 - 4.9e-96 322.0 2.7 4.9e-96 322.0 2.7 1.9 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.6 EGC39137.1 - 2.5e-29 101.1 2.4 5.5e-28 96.8 0.5 3.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.6 EGC39137.1 - 3.5e-29 101.3 0.6 3.5e-29 101.3 0.6 2.8 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.6 EGC39137.1 - 1.2e-24 86.3 1.2 4.4e-22 78.1 0.0 4.3 4 1 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Glyoxalase PF00903.25 EGC39138.1 - 2.8e-22 79.3 3.1 1.2e-15 57.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.6 EGC39138.1 - 3.5e-09 36.9 0.1 0.00075 19.7 0.1 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.6 EGC39138.1 - 1.2e-08 35.2 0.1 2.4e-08 34.2 0.1 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_3 PF13468.6 EGC39138.1 - 0.00097 19.3 0.1 3.3 7.8 0.0 3.7 3 1 0 3 3 3 2 Glyoxalase-like domain adh_short PF00106.25 EGC39139.1 - 2e-37 128.6 0.1 2.8e-37 128.1 0.1 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC39139.1 - 2.4e-28 99.3 0.0 3e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC39139.1 - 2e-06 27.8 0.0 2.8e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC39139.1 - 0.00057 19.3 0.0 0.0007 19.1 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.21 EGC39139.1 - 0.00069 19.1 0.0 0.0012 18.3 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC39139.1 - 0.0033 16.9 0.1 0.0048 16.3 0.1 1.2 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase 3Beta_HSD PF01073.19 EGC39139.1 - 0.014 14.4 0.4 0.024 13.6 0.4 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family MMM1 PF10296.9 EGC39141.1 - 8.5e-15 54.6 7.9 1.1e-14 54.2 1.9 2.4 2 1 0 2 2 2 1 Maintenance of mitochondrial morphology protein 1 DUF4834 PF16118.5 EGC39141.1 - 0.51 11.3 2.2 2.7 9.0 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Sad1_UNC PF07738.13 EGC39142.1 - 3.4e-30 104.7 0.4 1.2e-29 103.0 0.4 2.0 1 0 0 1 1 1 1 Sad1 / UNC-like C-terminal SUIM_assoc PF16619.5 EGC39142.1 - 0.042 13.9 0.4 0.042 13.9 0.4 6.9 5 1 0 5 5 5 0 Unstructured region C-term to UIM in Ataxin3 Kelch_6 PF13964.6 EGC39143.1 - 2.7e-10 40.2 0.4 0.00041 20.5 0.0 4.0 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.6 EGC39143.1 - 7.5e-09 35.5 0.1 0.0035 17.3 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.25 EGC39143.1 - 2.6e-07 30.1 0.0 0.029 13.9 0.0 2.9 2 0 0 2 2 2 2 Kelch motif zf-B_box PF00643.24 EGC39143.1 - 2e-06 27.8 12.9 2e-06 27.8 12.9 3.3 3 0 0 3 3 3 1 B-box zinc finger Kelch_5 PF13854.6 EGC39143.1 - 0.02 14.9 0.1 1.6 8.8 0.0 3.0 2 0 0 2 2 2 0 Kelch motif Androgen_recep PF02166.16 EGC39143.1 - 0.59 8.9 10.2 1.1 8.1 10.2 1.4 1 0 0 1 1 1 0 Androgen receptor Presenilin PF01080.17 EGC39143.1 - 1.6 7.4 11.0 3.2 6.4 11.0 1.5 1 0 0 1 1 1 0 Presenilin RFC1 PF08519.12 EGC39144.1 - 1.3e-44 152.1 0.2 7.1e-44 149.7 0.0 2.5 2 0 0 2 2 2 1 Replication factor RFC1 C terminal domain AAA PF00004.29 EGC39144.1 - 6.4e-12 46.0 0.2 3.4e-10 40.4 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.26 EGC39144.1 - 5e-10 39.6 0.0 1.7e-09 37.9 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.7 EGC39144.1 - 8.7e-06 25.6 0.1 2.2e-05 24.3 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.12 EGC39144.1 - 2.5e-05 24.1 0.0 5.3e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain BRCT_2 PF16589.5 EGC39144.1 - 0.00055 20.3 0.0 0.0033 17.8 0.0 2.4 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain AAA_16 PF13191.6 EGC39144.1 - 0.0033 17.8 0.0 0.0076 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.6 EGC39144.1 - 0.042 14.0 0.0 0.36 11.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain Glyco_hydro_18 PF00704.28 EGC39145.1 - 2.1e-61 208.4 1.5 2.4e-61 208.2 1.5 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_17 PF13431.6 EGC39146.1 - 3.6e-57 186.7 64.5 1.1e-06 28.6 1.8 18.3 18 0 0 18 18 18 13 Tetratricopeptide repeat zf-B_box PF00643.24 EGC39146.1 - 3.1e-07 30.4 6.4 3.1e-07 30.4 6.4 3.7 4 0 0 4 4 4 1 B-box zinc finger TPR_11 PF13414.6 EGC39146.1 - 0.00031 20.3 56.2 1 9.1 0.5 13.0 16 0 0 16 16 16 5 TPR repeat zf-RING_UBOX PF13445.6 EGC39146.1 - 0.0017 18.3 3.3 0.0066 16.5 3.3 2.1 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC39146.1 - 0.0089 16.0 7.7 0.0089 16.0 7.7 2.8 2 1 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC39146.1 - 0.016 15.0 2.2 0.016 15.0 2.2 3.2 3 0 0 3 3 3 0 Prokaryotic RING finger family 4 P66_CC PF16563.5 EGC39146.1 - 0.19 11.3 2.2 0.45 10.2 2.2 1.5 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 FYVE PF01363.21 EGC39146.1 - 1.4 9.2 15.3 0.5 10.5 4.5 2.7 3 0 0 3 3 3 0 FYVE zinc finger PIG-Y PF15159.6 EGC39147.1 - 3.2e-20 72.8 7.6 4.4e-20 72.4 7.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pex14_N PF04695.13 EGC39147.1 - 0.014 16.1 3.9 0.016 15.9 3.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PIG-P PF08510.12 EGC39147.1 - 4.1 7.3 7.6 7 6.6 7.6 1.3 1 0 0 1 1 1 0 PIG-P EF-hand_1 PF00036.32 EGC39148.1 - 2.1e-21 73.8 8.8 5.7e-06 25.5 0.7 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC39148.1 - 3.6e-21 75.4 1.5 7.9e-12 45.5 0.3 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.6 EGC39148.1 - 5e-19 66.6 4.2 3.8e-06 26.4 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC39148.1 - 1e-12 46.9 9.7 0.0001 21.6 0.3 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.6 EGC39148.1 - 9.8e-10 38.1 9.3 1.4e-05 24.9 2.1 4.4 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_11 PF08976.11 EGC39148.1 - 1.4e-05 25.9 0.2 0.00063 20.6 0.0 2.3 1 1 1 2 2 2 1 EF-hand domain EF-hand_4 PF12763.7 EGC39148.1 - 1.7e-05 24.7 2.6 0.15 12.1 0.1 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand Dockerin_1 PF00404.18 EGC39148.1 - 3.8e-05 23.8 4.8 0.15 12.2 1.6 3.3 1 1 2 3 3 3 3 Dockerin type I domain SPARC_Ca_bdg PF10591.9 EGC39148.1 - 5.9e-05 23.3 0.2 0.44 10.9 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.6 EGC39148.1 - 0.0002 21.6 0.1 0.095 13.0 0.0 2.9 3 0 0 3 3 3 1 EF-hand domain DUF3116 PF11313.8 EGC39148.1 - 0.08 12.8 0.0 0.23 11.4 0.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3116) Glyco_transf_10 PF00852.19 EGC39149.1 - 9.7e-32 110.1 3.1 1.9e-31 109.2 3.1 1.4 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) C-term Laminin_G_3 PF13385.6 EGC39149.1 - 2.3e-23 83.0 0.0 4.1e-23 82.2 0.0 1.4 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.16 EGC39149.1 - 0.00036 20.1 0.1 0.001 18.6 0.1 1.8 1 0 0 1 1 1 1 Sialidase, N-terminal domain TraF PF13728.6 EGC39149.1 - 0.085 12.7 0.4 17 5.2 0.1 2.7 3 0 0 3 3 3 0 F plasmid transfer operon protein DNA_methylase PF00145.17 EGC39149.1 - 0.1 12.0 0.0 0.1 12.0 0.0 3.3 2 1 0 3 3 3 0 C-5 cytosine-specific DNA methylase KbaA PF14089.6 EGC39151.1 - 0.089 12.6 0.0 0.091 12.6 0.0 1.0 1 0 0 1 1 1 0 KinB-signalling pathway activation in sporulation EF-hand_1 PF00036.32 EGC39152.1 - 9.8e-21 71.7 10.6 3e-06 26.4 0.6 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC39152.1 - 2.6e-20 72.6 9.3 9.7e-11 42.0 0.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC39152.1 - 2.9e-19 67.3 3.1 3.5e-05 23.4 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC39152.1 - 7.4e-11 41.0 4.0 0.0045 16.4 0.1 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGC39152.1 - 2.5e-10 40.0 5.8 0.0042 16.9 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC39152.1 - 1.7e-09 38.0 6.3 0.005 17.1 1.5 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGC39152.1 - 8.5e-06 25.8 1.6 0.0059 16.6 0.3 2.5 1 1 1 2 2 2 2 Caleosin related protein DUF1636 PF07845.11 EGC39152.1 - 0.0099 16.3 0.0 1.9 9.0 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF1636) FF PF01846.19 EGC39152.1 - 0.031 14.5 0.2 1.3 9.2 0.0 2.6 2 0 0 2 2 2 0 FF domain CBP4 PF07960.11 EGC39152.1 - 0.087 12.7 1.3 0.12 12.2 1.3 1.2 1 0 0 1 1 1 0 CBP4 EF-hand_1 PF00036.32 EGC39153.1 - 1.3e-24 83.9 13.1 9.9e-07 27.9 0.6 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.6 EGC39153.1 - 2.5e-21 75.9 11.5 2e-10 40.9 1.6 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC39153.1 - 5.1e-21 72.8 4.9 0.0001 22.0 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.6 EGC39153.1 - 5.1e-17 60.5 4.2 0.00045 19.6 0.1 4.3 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.6 EGC39153.1 - 1.5e-14 53.6 5.4 8.7e-05 22.3 0.3 4.3 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC39153.1 - 1.6e-08 34.9 6.6 0.0015 18.8 1.0 3.0 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region Caleosin PF05042.13 EGC39153.1 - 7.2e-06 26.0 2.2 0.003 17.5 0.2 2.6 1 1 0 2 2 2 2 Caleosin related protein DUF1636 PF07845.11 EGC39153.1 - 0.00072 20.0 0.0 0.92 10.0 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1636) FF PF01846.19 EGC39153.1 - 0.016 15.3 0.3 0.65 10.2 0.0 2.6 2 0 0 2 2 2 0 FF domain PgpA PF04608.13 EGC39153.1 - 0.033 14.2 0.1 2 8.5 0.0 2.7 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A NP1-WLL PF11733.8 EGC39153.1 - 0.034 13.9 0.8 0.12 12.1 0.1 1.8 1 1 1 2 2 2 0 Non-capsid protein NP1 DUF5109 PF17134.4 EGC39153.1 - 0.041 13.8 1.2 6.5 6.7 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF5109) EF-hand_13 PF17958.1 EGC39153.1 - 0.091 12.6 0.2 3.5 7.5 0.1 3.0 1 1 2 3 3 3 0 EF-hand domain DUF4777 PF16007.5 EGC39153.1 - 0.12 12.6 0.0 4.3 7.7 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4777) Dockerin_1 PF00404.18 EGC39153.1 - 0.16 12.2 5.0 2.8 8.2 0.3 3.4 3 1 1 4 4 4 0 Dockerin type I domain VbhA PF18495.1 EGC39153.1 - 0.19 11.6 0.4 1.4 8.8 0.0 2.4 3 0 0 3 3 3 0 Antitoxin VbhA CDC45 PF02724.14 EGC39154.1 - 1.9e-167 558.4 14.4 4.5e-167 557.2 14.4 1.5 1 1 0 1 1 1 1 CDC45-like protein YL1 PF05764.13 EGC39154.1 - 8.2e-06 26.1 21.1 1.3e-05 25.4 21.1 1.3 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.12 EGC39154.1 - 0.00094 17.5 22.2 0.0013 17.1 22.2 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.12 EGC39154.1 - 0.004 16.6 21.0 0.0061 16.0 21.0 1.2 1 0 0 1 1 1 1 SDA1 Nop53 PF07767.11 EGC39154.1 - 0.0075 15.7 19.5 0.012 15.0 19.5 1.2 1 0 0 1 1 1 1 Nop53 (60S ribosomal biogenesis) CLAMP PF14769.6 EGC39154.1 - 0.016 15.7 0.1 0.047 14.1 0.1 1.8 1 0 0 1 1 1 0 Flagellar C1a complex subunit C1a-32 Presenilin PF01080.17 EGC39154.1 - 0.18 10.5 11.3 0.28 9.9 11.3 1.2 1 0 0 1 1 1 0 Presenilin RRN3 PF05327.11 EGC39154.1 - 1 7.9 15.6 1.5 7.3 15.6 1.3 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DNA_pol_phi PF04931.13 EGC39154.1 - 2.8 5.9 29.2 4.9 5.1 29.2 1.4 1 0 0 1 1 1 0 DNA polymerase phi MDM10 PF12519.8 EGC39154.1 - 4.7 6.0 11.1 7.4 5.3 11.1 1.3 1 0 0 1 1 1 0 Mitochondrial distribution and morphology protein 10 BUD22 PF09073.10 EGC39154.1 - 5.6 6.2 23.9 9.2 5.5 23.9 1.3 1 0 0 1 1 1 0 BUD22 ALMT PF11744.8 EGC39154.1 - 7.2 5.3 8.7 15 4.2 8.7 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter dUTPase PF00692.19 EGC39155.1 - 3.7e-05 23.4 0.0 6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 dUTPase VCBS PF13517.6 EGC39156.1 - 1.4e-29 102.5 33.8 3.9e-11 43.4 2.4 6.0 3 1 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella UnbV_ASPIC PF07593.12 EGC39156.1 - 1.2e-17 63.6 0.0 2.5e-17 62.6 0.0 1.6 1 0 0 1 1 1 1 ASPIC and UnbV FG-GAP PF01839.23 EGC39156.1 - 2.4e-17 62.7 11.7 0.00034 20.7 0.3 7.7 7 0 0 7 7 7 4 FG-GAP repeat EF-hand_6 PF13405.6 EGC39156.1 - 6.3 7.0 11.4 56 4.1 0.0 5.5 5 0 0 5 5 5 0 EF-hand domain SHS2_Rpb7-N PF03876.17 EGC39157.1 - 2.7e-07 30.9 0.0 4.2e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RPA43_OB PF17875.1 EGC39157.1 - 3.1e-07 31.0 0.0 5.1e-07 30.4 0.0 1.4 1 1 0 1 1 1 1 RPA43 OB domain in RNA Pol I RNA_pol_Rbc25 PF08292.12 EGC39157.1 - 0.0021 18.3 0.1 0.0035 17.6 0.1 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 Keratin_assoc PF09775.9 EGC39157.1 - 0.0082 15.8 1.0 0.013 15.1 1.0 1.4 1 1 0 1 1 1 1 Keratinocyte-associated protein 2 F_actin_cap_B PF01115.17 EGC39158.1 - 1.3e-103 345.8 0.2 1.5e-103 345.6 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Noelin-1 PF12308.8 EGC39158.1 - 0.061 13.3 0.1 0.15 12.1 0.1 1.6 1 0 0 1 1 1 0 Neurogenesis glycoprotein DUF3870 PF12986.7 EGC39158.1 - 0.068 13.4 0.2 0.17 12.1 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3870) Nas2_N PF18265.1 EGC39158.1 - 0.12 12.3 0.0 0.35 10.8 0.0 1.9 1 0 0 1 1 1 0 Nas2 N_terminal domain Cellulase PF00150.18 EGC39159.1 - 1e-28 100.6 1.4 2.2e-28 99.5 1.4 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ASF1_hist_chap PF04729.13 EGC39160.1 - 1.4e-65 219.9 0.0 1.5e-65 219.8 0.0 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Isy1 PF06246.12 EGC39161.1 - 1.8e-84 283.3 17.0 2.1e-84 283.1 17.0 1.0 1 0 0 1 1 1 1 Isy1-like splicing family DUF4094 PF13334.6 EGC39161.1 - 0.54 10.7 0.1 0.54 10.7 0.1 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF4094) FG-GAP PF01839.23 EGC39162.1 - 7.9e-21 73.9 38.2 0.0018 18.4 0.8 7.5 7 0 0 7 7 7 7 FG-GAP repeat VCBS PF13517.6 EGC39162.1 - 1e-17 64.4 41.6 4.7e-06 27.1 4.0 5.5 2 1 4 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EGF_2 PF07974.13 EGC39162.1 - 5.4e-13 49.0 71.7 0.00074 19.8 9.7 4.5 4 0 0 4 4 4 4 EGF-like domain TcdB_toxin_midN PF12256.8 EGC39162.1 - 0.00014 21.3 5.6 9.3 5.6 0.0 5.3 4 1 1 5 5 5 3 Insecticide toxin TcdB middle/N-terminal region Insulin_TMD PF17870.1 EGC39162.1 - 0.25 11.4 1.7 0.79 9.8 1.7 1.8 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Laminin_EGF PF00053.24 EGC39162.1 - 6.3 7.0 60.2 0.77 9.9 10.2 4.4 2 1 2 4 4 4 0 Laminin EGF domain EGF PF00008.27 EGC39162.1 - 9.2 6.7 58.3 0.54 10.6 7.9 4.8 5 0 0 5 5 5 0 EGF-like domain Peptidase_C12 PF01088.21 EGC39163.1 - 9.2e-68 228.1 0.7 2.3e-67 226.8 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 UCH_C PF18031.1 EGC39163.1 - 1.1e-18 66.9 2.4 1.1e-18 66.9 2.4 2.7 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolases CLP1_P PF16575.5 EGC39164.1 - 1.3e-61 207.7 0.0 5.6e-61 205.6 0.0 1.9 2 0 0 2 2 2 1 mRNA cleavage and polyadenylation factor CLP1 P-loop Clp1 PF06807.14 EGC39164.1 - 1.1e-29 103.2 0.0 1.9e-29 102.5 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 CLP1_N PF16573.5 EGC39164.1 - 3e-25 88.3 0.1 4.7e-25 87.6 0.1 1.3 1 0 0 1 1 1 1 N-terminal beta-sandwich domain of polyadenylation factor AAA_24 PF13479.6 EGC39164.1 - 0.0016 18.2 0.0 0.0034 17.1 0.0 1.6 2 0 0 2 2 2 1 AAA domain CbiA PF01656.23 EGC39164.1 - 0.003 17.6 0.0 0.005 16.9 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ATP_bind_1 PF03029.17 EGC39164.1 - 0.075 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.7 EGC39164.1 - 0.12 11.3 0.0 0.19 10.6 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_35 PF14516.6 EGC39164.1 - 0.16 10.8 0.0 0.25 10.1 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain ParA PF10609.9 EGC39165.1 - 1e-100 336.3 0.1 1.3e-100 336.0 0.1 1.0 1 0 0 1 1 1 1 NUBPL iron-transfer P-loop NTPase CbiA PF01656.23 EGC39165.1 - 2.4e-09 37.3 0.0 9e-09 35.5 0.0 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.6 EGC39165.1 - 1.3e-07 31.7 0.2 1.5e-06 28.2 0.2 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.15 EGC39165.1 - 6.1e-06 25.6 0.9 9.2e-05 21.8 0.9 2.2 1 1 0 1 1 1 1 Anion-transporting ATPase RsgA_GTPase PF03193.16 EGC39165.1 - 0.00015 21.7 0.2 0.0035 17.3 0.0 2.3 2 0 0 2 2 2 1 RsgA GTPase MipZ PF09140.11 EGC39165.1 - 0.0016 17.8 0.0 0.0064 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ AAA_25 PF13481.6 EGC39165.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Fer4_NifH PF00142.18 EGC39165.1 - 0.0064 16.0 0.1 0.19 11.1 0.0 2.5 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_24 PF13479.6 EGC39165.1 - 0.0084 15.8 0.0 0.015 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.22 EGC39165.1 - 0.036 13.3 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain CBP_BcsQ PF06564.12 EGC39165.1 - 0.092 12.2 0.1 0.64 9.5 0.1 2.0 1 1 0 1 1 1 0 Cellulose biosynthesis protein BcsQ PcrB PF01884.17 EGC39165.1 - 0.11 12.0 0.0 0.16 11.4 0.0 1.3 1 0 0 1 1 1 0 PcrB family Rad17 PF03215.15 EGC39165.1 - 0.11 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 Rad17 P-loop domain MeaB PF03308.16 EGC39165.1 - 0.14 11.2 0.0 0.21 10.6 0.0 1.2 1 0 0 1 1 1 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NACHT PF05729.12 EGC39165.1 - 0.2 11.6 0.1 0.34 10.8 0.1 1.3 1 0 0 1 1 1 0 NACHT domain Zn_Tnp_IS1595 PF12760.7 EGC39165.1 - 0.48 10.5 2.0 0.55 10.2 0.0 2.1 3 0 0 3 3 2 0 Transposase zinc-ribbon domain Pkinase PF00069.25 EGC39166.1 - 1e-35 123.4 0.4 3.2e-23 82.4 0.5 4.0 5 0 0 5 5 5 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39166.1 - 1.4e-16 60.5 0.2 1.6e-08 34.1 0.4 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Spore_III_AF PF09581.10 EGC39167.1 - 0.58 10.2 4.4 0.11 12.5 0.3 1.9 2 0 0 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) zf_CCCH_4 PF18345.1 EGC39168.1 - 1.9e-10 40.4 17.9 9.1e-06 25.6 4.8 3.0 3 0 0 3 3 3 2 Zinc finger domain zf-CCCH PF00642.24 EGC39168.1 - 9.4e-08 31.8 15.5 6e-06 26.0 0.7 3.4 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_4 PF18044.1 EGC39168.1 - 1.4e-07 31.1 15.8 2.9e-07 30.1 1.7 3.3 3 0 0 3 3 3 2 CCCH-type zinc finger zf-CCCH_3 PF15663.5 EGC39168.1 - 9.7e-06 25.8 1.9 9.7e-06 25.8 1.9 2.7 2 0 0 2 2 2 1 Zinc-finger containing family zf-CCCH_2 PF14608.6 EGC39168.1 - 4.5e-05 23.8 22.1 0.055 14.0 3.3 3.5 3 0 0 3 3 3 3 RNA-binding, Nab2-type zinc finger Torus PF16131.5 EGC39168.1 - 0.039 14.6 40.1 0.053 14.2 2.3 4.6 1 1 2 3 3 3 0 Torus domain Secretin_N_2 PF07655.13 EGC39169.1 - 0.024 15.2 9.7 0.026 15.0 9.7 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain NST1 PF13945.6 EGC39169.1 - 0.23 11.6 13.9 0.24 11.5 13.9 1.0 1 0 0 1 1 1 0 Salt tolerance down-regulator Menin PF05053.13 EGC39169.1 - 0.66 8.3 7.2 0.66 8.3 7.2 1.0 1 0 0 1 1 1 0 Menin DUF4175 PF13779.6 EGC39169.1 - 2 6.2 8.9 2.5 5.9 8.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) NTF2 PF02136.20 EGC39170.1 - 6.3e-29 101.0 0.0 6.9e-29 100.9 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain dCMP_cyt_deam_1 PF00383.23 EGC39171.1 - 1.4e-13 50.5 0.3 2.5e-13 49.7 0.3 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region MafB19-deam PF14437.6 EGC39171.1 - 8.6e-09 35.3 0.3 1.7e-08 34.3 0.3 1.4 1 1 0 1 1 1 1 MafB19-like deaminase zf-TFIIB PF13453.6 EGC39171.1 - 0.02 14.2 0.1 0.045 13.1 0.1 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger Lar_restr_allev PF14354.6 EGC39171.1 - 0.033 14.6 2.3 0.17 12.3 0.1 2.5 3 0 0 3 3 3 0 Restriction alleviation protein Lar TALPID3 PF15324.6 EGC39173.1 - 3.5 5.2 5.1 4.2 4.9 5.1 1.1 1 0 0 1 1 1 0 Hedgehog signalling target SpoVAC_SpoVAEB PF03862.13 EGC39174.1 - 0.027 14.8 3.9 0.041 14.2 3.9 1.2 1 0 0 1 1 1 0 SpoVAC/SpoVAEB sporulation membrane protein VPS13_mid_rpt PF16910.5 EGC39174.1 - 0.031 13.7 3.6 0.045 13.2 3.6 1.2 1 0 0 1 1 1 0 Repeating coiled region of VPS13 Wzy_C PF04932.15 EGC39174.1 - 0.036 13.7 1.6 0.11 12.1 0.6 2.0 2 0 0 2 2 2 0 O-Antigen ligase LapA_dom PF06305.11 EGC39174.1 - 0.31 10.9 5.4 0.41 10.5 0.8 2.8 1 1 2 3 3 3 0 Lipopolysaccharide assembly protein A domain P5CR_dimer PF14748.6 EGC39175.1 - 2.2e-24 85.7 0.9 3.8e-24 84.9 0.9 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.17 EGC39175.1 - 1.7e-16 60.6 0.3 3.5e-16 59.6 0.3 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.23 EGC39175.1 - 9.6e-08 32.2 0.0 2e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.16 EGC39175.1 - 2.7e-05 23.8 0.9 0.00035 20.2 0.2 2.6 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.15 EGC39175.1 - 3.8e-05 23.9 0.0 0.00012 22.2 0.0 1.9 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase Sacchrp_dh_NADP PF03435.18 EGC39175.1 - 0.022 15.0 0.1 0.051 13.8 0.1 1.8 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain VP4_helical PF17478.2 EGC39175.1 - 0.024 14.1 1.5 0.12 11.8 1.5 1.9 1 1 0 1 1 1 0 Rotavirus VP4 helical domain Myelin_PLP PF01275.19 EGC39175.1 - 0.54 10.1 6.2 0.87 9.4 6.2 1.3 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) RhoGAP PF00620.27 EGC39176.1 - 1.7e-18 66.9 0.0 2.7e-17 63.0 0.1 2.5 2 1 0 2 2 2 1 RhoGAP domain TIP41 PF04176.13 EGC39178.1 - 4.6e-64 215.1 0.6 6.7e-64 214.5 0.6 1.3 1 0 0 1 1 1 1 TIP41-like family ACPS PF01648.20 EGC39180.1 - 3.1e-18 66.0 0.6 8.5e-18 64.5 0.1 2.0 3 0 0 3 3 3 1 4'-phosphopantetheinyl transferase superfamily TMEM164 PF14808.6 EGC39181.1 - 8.5e-08 31.8 11.2 6e-07 29.1 9.2 2.4 2 1 0 2 2 2 1 TMEM164 family Intg_mem_TP0381 PF09529.10 EGC39181.1 - 0.00017 21.2 18.2 0.00017 21.2 18.2 2.3 3 1 0 3 3 3 1 Integral membrane protein (intg_mem_TP0381) DUF3671 PF12420.8 EGC39181.1 - 2.9 8.0 10.1 0.21 11.7 1.6 3.0 2 1 2 4 4 4 0 Protein of unknown function Exo_endo_phos PF03372.23 EGC39182.1 - 7.1e-05 22.4 0.0 0.00011 21.8 0.0 1.4 1 1 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.6 EGC39182.1 - 0.072 12.9 0.1 1.5 8.7 0.1 2.4 1 1 0 1 1 1 0 Endonuclease-reverse transcriptase ABC2_membrane PF01061.24 EGC39183.1 - 1.7e-84 282.4 63.8 2e-47 161.3 21.1 2.9 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.27 EGC39183.1 - 7.9e-39 133.3 0.0 3.1e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.12 EGC39183.1 - 5e-22 77.6 0.1 5e-22 77.6 0.1 4.7 5 0 0 5 5 3 2 CDR ABC transporter ABC_trans_N PF14510.6 EGC39183.1 - 1.9e-11 44.4 0.0 4.6e-11 43.2 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter N-terminal RsgA_GTPase PF03193.16 EGC39183.1 - 1.3e-06 28.4 0.1 0.00032 20.6 0.1 2.4 2 0 0 2 2 2 1 RsgA GTPase AAA_29 PF13555.6 EGC39183.1 - 4e-06 26.5 0.3 0.0061 16.3 0.1 2.8 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_21 PF13304.6 EGC39183.1 - 4.3e-05 23.5 0.0 0.21 11.3 0.0 2.8 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system AAA_16 PF13191.6 EGC39183.1 - 4.9e-05 23.8 0.1 0.021 15.2 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain ABC2_membrane_3 PF12698.7 EGC39183.1 - 0.00041 19.6 12.5 0.00041 19.6 12.5 4.5 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_22 PF13401.6 EGC39183.1 - 0.00096 19.4 0.0 0.42 10.9 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.6 EGC39183.1 - 0.0023 17.6 0.3 0.0058 16.2 0.1 1.7 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.23 EGC39183.1 - 0.0032 17.5 0.0 3.1 7.9 0.0 2.6 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_33 PF13671.6 EGC39183.1 - 0.004 17.3 0.0 1.1 9.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain TMEM154 PF15102.6 EGC39183.1 - 0.008 16.1 0.6 0.057 13.3 0.8 2.2 2 0 0 2 2 2 1 TMEM154 protein family cobW PF02492.19 EGC39183.1 - 0.012 15.2 0.7 1.2 8.6 0.2 2.5 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.6 EGC39183.1 - 0.025 14.3 0.2 2.4 7.9 0.3 2.3 2 0 0 2 2 2 0 AAA domain Peptidase_M56 PF05569.11 EGC39183.1 - 0.027 13.7 0.2 0.77 8.9 0.2 2.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 AAA_18 PF13238.6 EGC39183.1 - 0.043 14.4 2.6 0.63 10.6 0.0 3.5 4 0 0 4 4 3 0 AAA domain DUF3377 PF11857.8 EGC39183.1 - 0.045 13.7 0.1 0.045 13.7 0.1 2.3 2 0 0 2 2 1 0 Domain of unknown function (DUF3377) Zeta_toxin PF06414.12 EGC39183.1 - 0.047 13.0 0.0 2.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.29 EGC39183.1 - 0.078 13.4 0.9 7.2 7.0 0.2 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.22 EGC39183.1 - 0.098 13.1 0.0 25 5.3 0.0 2.9 2 0 0 2 2 2 0 RNA helicase NACHT PF05729.12 EGC39183.1 - 0.12 12.2 0.3 8 6.3 0.3 2.5 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.6 EGC39183.1 - 0.41 11.1 13.4 1.3 9.5 0.1 4.7 5 0 0 5 5 5 0 AAA domain Colicin-DNase PF12639.7 EGC39183.1 - 1.7 9.5 4.6 0.37 11.6 0.3 2.2 2 0 0 2 2 1 0 DNase/tRNase domain of colicin-like bacteriocin FNIP PF05725.12 EGC39185.1 - 1.6e-71 236.2 53.8 3.6e-13 49.5 1.3 9.9 4 2 6 11 11 11 11 FNIP Repeat RVT_1 PF00078.27 EGC39187.1 - 4.6e-39 134.2 0.7 4.6e-39 134.2 0.7 1.8 2 0 0 2 2 2 1 Reverse transcriptase (RNA-dependent DNA polymerase) zf-RVT PF13966.6 EGC39187.1 - 2.5 8.9 6.3 0.79 10.5 0.3 3.0 3 0 0 3 3 3 0 zinc-binding in reverse transcriptase GWT1 PF06423.12 EGC39189.1 - 2.3e-30 105.7 12.6 2.3e-30 105.7 12.6 3.1 2 1 0 2 2 2 1 GWT1 CrgA PF06781.12 EGC39189.1 - 0.063 13.3 0.0 0.063 13.3 0.0 3.4 4 1 1 5 5 5 0 Cell division protein CrgA DUF3624 PF12292.8 EGC39189.1 - 2.9 8.3 6.5 0.35 11.3 1.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) Far-17a_AIG1 PF04750.14 EGC39190.1 - 8e-29 100.4 14.5 1.2e-20 73.7 7.0 2.1 2 0 0 2 2 2 2 FAR-17a/AIG1-like protein Pex2_Pex12 PF04757.14 EGC39191.1 - 3e-64 216.7 12.8 4.6e-64 216.1 12.8 1.3 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_3 PF13920.6 EGC39191.1 - 0.00061 19.6 3.5 0.00096 19.0 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39191.1 - 0.0026 17.5 4.6 0.0049 16.7 4.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39191.1 - 0.032 14.6 5.4 0.063 13.6 5.4 1.5 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.25 EGC39191.1 - 0.063 13.2 5.3 0.13 12.1 5.3 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC39191.1 - 1.1 9.5 7.9 2 8.6 7.9 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.6 EGC39191.1 - 1.9 8.6 8.7 4.1 7.5 8.7 1.5 1 0 0 1 1 1 0 RING-type zinc-finger CoaE PF01121.20 EGC39192.1 - 3.1e-44 150.8 0.0 4e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.6 EGC39192.1 - 6.4e-05 23.5 1.0 0.00023 21.7 0.5 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.6 EGC39192.1 - 0.00052 20.3 0.0 0.0026 18.0 0.0 1.9 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.6 EGC39192.1 - 0.0032 17.6 0.7 0.0053 16.9 0.7 1.6 1 1 0 1 1 1 1 Cytidylate kinase-like family AAA_33 PF13671.6 EGC39192.1 - 0.017 15.3 0.0 0.14 12.3 0.0 2.2 1 1 0 1 1 1 0 AAA domain dNK PF01712.19 EGC39192.1 - 0.35 10.7 3.7 3.6 7.4 0.3 3.0 2 1 1 3 3 3 0 Deoxynucleoside kinase Aminotran_4 PF01063.19 EGC39193.1 - 3.1e-33 115.5 0.0 3.8e-33 115.2 0.0 1.1 1 0 0 1 1 1 1 Amino-transferase class IV Pkinase PF00069.25 EGC39194.1 - 4.7e-77 258.9 0.0 3.2e-76 256.2 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39194.1 - 2.9e-49 167.7 0.0 5.4e-49 166.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC39194.1 - 2e-07 30.2 0.0 2.2e-06 26.7 0.0 2.2 2 0 0 2 2 2 1 Fungal protein kinase RIO1 PF01163.22 EGC39194.1 - 0.001 18.7 0.1 0.002 17.7 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kinase-like PF14531.6 EGC39194.1 - 0.0044 16.4 0.0 0.012 14.9 0.0 1.7 2 0 0 2 2 2 1 Kinase-like V-ATPase_H_C PF11698.8 EGC39194.1 - 0.011 15.8 3.9 3.4 7.8 0.7 3.1 2 1 0 2 2 2 0 V-ATPase subunit H Uso1_p115_head PF04869.14 EGC39194.1 - 0.029 13.5 2.9 0.54 9.3 0.1 2.8 3 0 0 3 3 3 0 Uso1 / p115 like vesicle tethering protein, head region Kdo PF06293.14 EGC39194.1 - 0.06 12.7 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF5584 PF17822.1 EGC39194.1 - 0.12 11.9 0.3 0.26 10.7 0.3 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5584) FTA2 PF13095.6 EGC39194.1 - 0.14 11.8 0.8 0.21 11.2 0.0 1.7 2 0 0 2 2 2 0 Kinetochore Sim4 complex subunit FTA2 HEAT PF02985.22 EGC39194.1 - 0.17 12.2 0.0 21 5.7 0.0 3.6 2 0 0 2 2 2 0 HEAT repeat BLOC1_2 PF10046.9 EGC39194.1 - 0.19 12.0 0.1 0.19 12.0 0.1 2.5 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 CSTF2_hinge PF14327.6 EGC39194.1 - 0.2 12.1 4.2 0.35 11.4 0.6 3.0 2 0 0 2 2 2 0 Hinge domain of cleavage stimulation factor subunit 2 RTTN_N PF14726.6 EGC39194.1 - 0.25 12.2 3.1 8.7 7.2 0.2 4.0 2 1 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning DUF2603 PF10788.9 EGC39194.1 - 4.8 7.2 9.7 0.095 12.7 0.4 2.7 3 0 0 3 3 2 0 Protein of unknown function (DUF2603) CDC50 PF03381.15 EGC39195.1 - 2.1e-87 293.2 0.5 2.1e-87 293.2 0.5 1.7 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family CrgA PF06781.12 EGC39195.1 - 0.032 14.3 1.0 4.4 7.4 0.3 2.4 2 0 0 2 2 2 0 Cell division protein CrgA DUF3185 PF11381.8 EGC39195.1 - 0.035 14.1 3.3 1.6 8.8 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) DUF4064 PF13273.6 EGC39195.1 - 0.091 13.0 2.2 9 6.6 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) adh_short PF00106.25 EGC39196.1 - 6.7e-34 117.1 0.1 9.6e-34 116.5 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC39196.1 - 1.3e-29 103.4 0.1 1.8e-29 102.9 0.1 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC39196.1 - 1.4e-06 28.3 0.1 2.4e-06 27.6 0.1 1.3 1 0 0 1 1 1 1 KR domain 2-Hacid_dh_C PF02826.19 EGC39196.1 - 0.12 11.7 0.2 0.27 10.6 0.2 1.7 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Epimerase PF01370.21 EGC39196.1 - 0.14 11.6 0.0 0.23 10.9 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NDT80_PhoG PF05224.12 EGC39197.1 - 4.2e-20 72.8 0.6 4.2e-20 72.8 0.6 5.4 2 2 1 3 3 3 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.6 EGC39197.1 - 3.3e-10 40.1 0.3 8e-10 38.9 0.3 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.6 EGC39197.1 - 6.3e-08 31.6 0.3 1.9e-07 30.1 0.3 1.9 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 TRAF_BIRC3_bd PF16673.5 EGC39197.1 - 0.022 14.6 0.3 0.066 13.0 0.3 1.8 1 0 0 1 1 1 0 TNF receptor-associated factor BIRC3 binding domain DUF3439 PF11921.8 EGC39197.1 - 9.6 6.2 9.3 18 5.4 3.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PKcGMP_CC PF16808.5 EGC39198.1 - 0.00021 21.1 3.1 0.00023 21.0 0.8 2.2 2 0 0 2 2 2 1 Coiled-coil N-terminus of cGMP-dependent protein kinase CALCOCO1 PF07888.11 EGC39198.1 - 0.019 13.9 12.7 0.023 13.6 12.7 1.0 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like BST2 PF16716.5 EGC39198.1 - 0.11 13.1 19.8 3.8 8.2 0.4 2.9 2 1 0 2 2 2 0 Bone marrow stromal antigen 2 TMCO5 PF14992.6 EGC39198.1 - 0.15 11.7 21.8 0.015 14.9 11.8 2.1 2 0 0 2 2 2 0 TMCO5 family CPSase_L_D3 PF02787.19 EGC39198.1 - 0.18 12.1 6.4 0.047 14.0 2.8 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain UPF0242 PF06785.11 EGC39198.1 - 0.87 9.7 28.6 1.6 8.8 4.8 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0242) N-terminus Cep57_CLD_2 PF14197.6 EGC39198.1 - 1.1 9.4 19.6 0.26 11.4 2.7 3.7 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 TPR_MLP1_2 PF07926.12 EGC39198.1 - 2.2 8.3 26.1 1 9.4 2.7 3.4 2 1 1 3 3 3 0 TPR/MLP1/MLP2-like protein Csm1_N PF18504.1 EGC39198.1 - 4.3 7.8 22.7 2.3 8.6 2.5 3.5 2 1 1 3 3 3 0 Csm1 N-terminal domain PRKG1_interact PF15898.5 EGC39198.1 - 8.1 7.4 21.0 10 7.1 8.8 2.7 1 1 1 2 2 2 0 cGMP-dependent protein kinase interacting domain Ank_2 PF12796.7 EGC39199.1 - 6.6e-16 58.7 2.3 9.5e-07 29.3 0.5 4.0 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC39199.1 - 4.5e-13 49.4 1.6 0.00011 22.6 0.0 5.0 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC39199.1 - 1e-09 37.8 0.1 0.0029 18.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGC39199.1 - 1.6e-09 37.8 0.2 2.9e-07 30.6 0.0 4.1 3 2 1 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC39199.1 - 3.6e-06 27.2 0.0 0.00038 20.8 0.0 3.3 2 0 0 2 2 2 1 Ankyrin repeat Mucin PF01456.17 EGC39199.1 - 5.5 7.0 11.8 12 5.9 11.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Cnd3 PF12719.7 EGC39200.1 - 4.8e-53 180.3 8.9 4.8e-53 180.3 8.9 4.5 4 1 1 5 5 5 3 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.6 EGC39200.1 - 0.00088 19.6 0.0 0.072 13.5 0.0 3.6 3 1 1 4 4 4 1 HEAT repeats DNA_binding_1 PF01035.20 EGC39202.1 - 1.1e-22 79.9 0.0 1.7e-22 79.3 0.0 1.3 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.15 EGC39202.1 - 0.095 13.5 0.0 0.22 12.4 0.0 1.6 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain HALZ PF02183.18 EGC39203.1 - 0.0038 17.4 8.4 0.008 16.4 1.2 4.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper TUG-UBL1 PF11470.8 EGC39203.1 - 0.0089 16.2 2.0 0.3 11.4 0.1 3.4 4 0 0 4 4 4 1 TUG ubiquitin-like domain TPR_MLP1_2 PF07926.12 EGC39203.1 - 0.54 10.3 77.5 0.62 10.1 3.8 5.3 2 1 3 5 5 5 0 TPR/MLP1/MLP2-like protein BicD PF09730.9 EGC39203.1 - 1.1 7.7 57.6 3.1 6.1 20.0 2.8 1 1 2 3 3 3 0 Microtubule-associated protein Bicaudal-D APG12 PF04110.13 EGC39203.1 - 3 8.3 6.8 98 3.5 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-like autophagy protein Apg12 Pkinase PF00069.25 EGC39204.1 - 1.3e-51 175.6 0.1 4.4e-51 173.8 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39204.1 - 3.1e-51 174.1 0.0 5.1e-51 173.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.19 EGC39204.1 - 3.6e-14 53.0 2.3 1.5e-13 51.0 2.3 2.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain ANAPC_CDC26 PF10471.9 EGC39204.1 - 0.002 18.9 2.7 0.002 18.9 2.7 5.7 5 0 0 5 5 5 1 Anaphase-promoting complex APC subunit CDC26 APH PF01636.23 EGC39204.1 - 0.02 14.8 0.1 1.2 9.0 0.1 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family Androgen_recep PF02166.16 EGC39204.1 - 0.025 13.5 3.2 0.044 12.6 3.2 1.3 1 0 0 1 1 1 0 Androgen receptor Trypan_PARP PF05887.11 EGC39204.1 - 0.65 10.0 6.1 1.8 8.5 6.1 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) HbrB PF08539.11 EGC39204.1 - 1.4 8.9 0.0 1.4 8.9 0.0 4.2 4 0 0 4 4 4 0 HbrB-like eIF3_subunit PF08597.10 EGC39204.1 - 2.3 8.1 16.1 5.3 6.9 16.1 1.6 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FNIP PF05725.12 EGC39205.1 - 1.7e-89 293.8 39.9 5.7e-16 58.4 3.4 7.1 5 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.10 EGC39205.1 - 0.00058 20.0 6.8 10 6.4 0.0 6.1 5 1 1 6 6 6 2 Protein of unknown function (DUF1769) Nop16 PF09420.10 EGC39206.1 - 2.7e-12 47.2 7.6 2.1e-11 44.3 1.6 3.6 2 2 1 3 3 3 2 Ribosome biogenesis protein Nop16 Mucin PF01456.17 EGC39206.1 - 0.076 13.0 7.4 0.1 12.6 7.4 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein GAGA_bind PF06217.12 EGC39206.1 - 0.19 12.0 17.3 0.26 11.5 17.3 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family PTPRCAP PF15713.5 EGC39206.1 - 0.34 11.2 8.5 0.52 10.6 8.5 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated DDHD PF02862.17 EGC39206.1 - 1 9.4 10.5 1.7 8.8 10.5 1.3 1 0 0 1 1 1 0 DDHD domain DUF2407_C PF13373.6 EGC39206.1 - 1.6 8.9 4.9 2.9 8.1 4.9 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Presenilin PF01080.17 EGC39206.1 - 4.6 5.9 13.2 5.6 5.6 13.2 1.1 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGC39206.1 - 5.6 5.7 14.6 6.8 5.4 14.6 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Rhodanese PF00581.20 EGC39208.1 - 9.7e-08 32.5 0.0 2.2e-07 31.4 0.0 1.6 1 1 0 1 1 1 1 Rhodanese-like domain AAA PF00004.29 EGC39209.1 - 7.6e-39 133.2 0.0 1.2e-38 132.5 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC39209.1 - 1.2e-10 41.0 0.1 2.6e-10 39.9 0.1 1.6 1 0 0 1 1 1 1 AAA+ lid domain Vps4_C PF09336.10 EGC39209.1 - 1.7e-07 31.1 0.0 3e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.12 EGC39209.1 - 2e-06 27.6 0.0 4.2e-06 26.6 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain TIP49 PF06068.13 EGC39209.1 - 5.2e-05 22.6 0.1 0.00016 21.0 0.0 1.8 1 1 1 2 2 2 1 TIP49 P-loop domain AAA_5 PF07728.14 EGC39209.1 - 6.6e-05 22.9 0.2 0.00064 19.7 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGC39209.1 - 0.00014 22.1 0.7 0.036 14.3 0.1 2.6 2 1 0 3 3 3 1 AAA domain AAA_25 PF13481.6 EGC39209.1 - 0.0008 19.0 0.2 0.17 11.4 0.1 2.4 1 1 2 3 3 3 1 AAA domain AAA_16 PF13191.6 EGC39209.1 - 0.0036 17.7 0.0 0.0071 16.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain Bac_DnaA PF00308.18 EGC39209.1 - 0.0047 16.8 0.1 0.037 13.9 0.1 2.0 1 1 0 1 1 1 1 Bacterial dnaA protein Mg_chelatase PF01078.21 EGC39209.1 - 0.0049 16.3 0.1 0.01 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.14 EGC39209.1 - 0.0051 16.9 0.0 0.013 15.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.6 EGC39209.1 - 0.0055 17.3 0.1 0.01 16.4 0.1 1.7 1 1 0 1 1 1 1 AAA domain TniB PF05621.11 EGC39209.1 - 0.013 14.9 0.1 2.4 7.6 0.0 2.4 1 1 0 2 2 2 0 Bacterial TniB protein IstB_IS21 PF01695.17 EGC39209.1 - 0.015 15.0 0.0 0.027 14.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.6 EGC39209.1 - 0.023 15.0 0.1 0.042 14.2 0.1 1.7 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.22 EGC39209.1 - 0.029 14.7 0.0 0.083 13.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_7 PF12775.7 EGC39209.1 - 0.044 13.3 0.0 0.1 12.1 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_24 PF13479.6 EGC39209.1 - 0.056 13.2 2.0 0.58 9.8 0.4 2.4 2 1 0 2 2 2 0 AAA domain Ribosomal_L50 PF10501.9 EGC39209.1 - 0.073 13.2 0.0 0.14 12.3 0.0 1.4 1 0 0 1 1 1 0 Ribosomal subunit 39S Guanylate_kin PF00625.21 EGC39209.1 - 0.12 12.1 0.1 0.33 10.6 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase AAA_14 PF13173.6 EGC39209.1 - 0.13 12.3 0.0 0.21 11.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC39209.1 - 0.24 11.1 0.3 0.52 10.0 0.3 1.6 1 1 0 1 1 1 0 AAA domain zf-UBP PF02148.19 EGC39212.1 - 0.07 13.5 0.0 0.12 12.7 0.0 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein SET PF00856.28 EGC39214.1 - 3.5e-24 86.1 0.2 2.1e-23 83.6 0.2 1.9 1 1 0 1 1 1 1 SET domain Ricin_B_lectin PF00652.22 EGC39214.1 - 0.047 13.9 1.2 0.12 12.6 0.6 1.8 1 1 1 2 2 2 0 Ricin-type beta-trefoil lectin domain Histone PF00125.24 EGC39215.1 - 9.4e-52 174.8 1.5 1.1e-51 174.7 1.5 1.0 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T_C PF15511.6 EGC39215.1 - 8.1e-05 22.7 0.1 0.00014 21.9 0.1 1.5 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC39215.1 - 0.00017 21.9 0.0 0.00027 21.3 0.0 1.3 1 0 0 1 1 1 1 CENP-S protein PAF PF15715.5 EGC39215.1 - 0.00019 22.0 1.1 0.00023 21.8 1.1 1.1 1 0 0 1 1 1 1 PCNA-associated factor histone like domain DUF4603 PF15376.6 EGC39215.1 - 0.21 8.9 1.0 0.24 8.7 1.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4603) Symplekin_C PF12295.8 EGC39216.1 - 0.066 13.3 0.2 1.6 8.8 0.0 2.2 2 0 0 2 2 2 0 Symplekin tight junction protein C terminal DUF3349 PF11829.8 EGC39216.1 - 0.081 13.7 0.0 0.23 12.2 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) YtxH PF12732.7 EGC39217.1 - 0.08 13.5 3.5 32 5.2 3.5 2.8 1 1 0 1 1 1 0 YtxH-like protein DUF2278 PF10042.9 EGC39217.1 - 0.1 12.6 1.0 0.18 11.8 0.8 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) UPF0147 PF03685.13 EGC39217.1 - 0.32 11.1 7.9 0.5 10.5 1.3 3.6 1 1 3 4 4 4 0 Uncharacterised protein family (UPF0147) QIL1 PF15884.5 EGC39217.1 - 0.53 10.9 4.8 2.3 8.9 0.4 3.4 1 1 3 4 4 4 0 MICOS complex subunit MIC13, QIL1 GST_C_3 PF14497.6 EGC39217.1 - 0.96 9.7 4.7 5.1 7.4 0.1 2.9 1 1 1 2 2 2 0 Glutathione S-transferase, C-terminal domain DUF3886 PF13025.6 EGC39217.1 - 4.3 7.6 17.8 1 9.6 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3886) KxDL PF10241.9 EGC39217.1 - 6.7 7.1 12.8 0.94 9.8 6.2 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein HTH_47 PF16221.5 EGC39220.1 - 0.055 13.0 0.2 0.16 11.5 0.2 1.8 1 1 0 1 1 1 0 winged helix-turn-helix GPW_gp25 PF04965.14 EGC39220.1 - 0.099 12.4 0.0 0.099 12.4 0.0 1.1 1 0 0 1 1 1 0 Gene 25-like lysozyme Nic96 PF04097.14 EGC39221.1 - 2.8e-75 254.0 21.4 1.5e-74 251.6 21.4 1.9 1 1 0 1 1 1 1 Nup93/Nic96 AHSP PF09236.10 EGC39221.1 - 0.065 13.7 0.4 0.065 13.7 0.4 3.3 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein DAP_epimerase PF01678.19 EGC39223.1 - 2.4e-38 131.0 0.1 2.6e-23 82.5 0.1 2.3 2 0 0 2 2 2 2 Diaminopimelate epimerase Peptidase_M8 PF01457.16 EGC39224.1 - 6e-70 236.4 2.8 9.7e-70 235.7 2.8 1.3 1 1 0 1 1 1 1 Leishmanolysin AA_permease_2 PF13520.6 EGC39225.1 - 2.1e-38 132.3 35.1 2.6e-38 131.9 35.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC39225.1 - 7.1e-20 71.1 32.8 1.2e-19 70.3 32.8 1.4 1 1 0 1 1 1 1 Amino acid permease DUF2070 PF09843.9 EGC39225.1 - 1.1 7.5 12.1 0.43 8.8 1.6 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2070) Abhydrolase_2 PF02230.16 EGC39226.1 - 2.9e-50 171.1 0.0 3.2e-50 171.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGC39226.1 - 9.3e-07 28.7 0.0 2.9e-06 27.1 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Hydrolase_4 PF12146.8 EGC39226.1 - 0.00031 20.1 0.0 0.13 11.5 0.0 2.9 2 1 1 3 3 3 2 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC39226.1 - 0.00077 20.1 0.0 0.0044 17.7 0.0 1.8 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGC39226.1 - 0.0022 17.5 0.0 0.018 14.5 0.0 2.1 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.8 EGC39226.1 - 0.0099 15.5 0.0 0.015 14.9 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_1 PF00561.20 EGC39226.1 - 0.059 13.0 0.3 1.9 8.0 0.1 2.6 2 1 1 3 3 3 0 alpha/beta hydrolase fold Cutinase PF01083.22 EGC39226.1 - 0.059 13.3 0.0 0.086 12.8 0.0 1.3 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.13 EGC39226.1 - 0.081 12.8 0.0 0.1 12.5 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold Pkinase_Tyr PF07714.17 EGC39227.1 - 1.9e-06 27.4 0.0 8e-05 22.0 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.25 EGC39227.1 - 3.1e-05 23.5 0.5 0.00024 20.6 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Glyco_hydro_57 PF03065.15 EGC39228.1 - 3.9e-09 36.1 0.3 6.4e-09 35.4 0.0 1.5 2 0 0 2 2 2 1 Glycosyl hydrolase family 57 DUF1281 PF06924.11 EGC39228.1 - 8.1 5.9 7.2 25 4.3 0.0 2.7 2 1 0 3 3 3 0 Protein of unknown function (DUF1281) ALG11_N PF15924.5 EGC39229.1 - 9.9e-89 296.9 0.3 1.4e-88 296.4 0.3 1.2 1 0 0 1 1 1 1 ALG11 mannosyltransferase N-terminus Glycos_transf_1 PF00534.20 EGC39229.1 - 1.1e-30 106.5 0.2 1.6e-30 105.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.6 EGC39229.1 - 1.3e-14 54.8 0.0 2.1e-14 54.1 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.6 EGC39229.1 - 6.7e-05 23.2 0.0 0.00013 22.3 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 RE_AlwI PF09491.10 EGC39229.1 - 0.031 13.1 3.8 0.34 9.7 0.2 2.1 2 0 0 2 2 2 0 AlwI restriction endonuclease ODV-E18 PF10717.9 EGC39229.1 - 0.051 13.5 1.6 0.075 12.9 0.4 1.8 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Afaf PF15339.6 EGC39229.1 - 2.6 7.7 9.4 11 5.6 0.1 3.1 3 0 0 3 3 3 0 Acrosome formation-associated factor Ras PF00071.22 EGC39232.1 - 1.7e-51 174.1 0.0 2.1e-51 173.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39232.1 - 2.5e-22 79.3 0.0 4.5e-22 78.5 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39232.1 - 2.4e-11 43.4 0.0 3.3e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC39232.1 - 1.3e-05 24.8 0.1 0.0001 21.9 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC39232.1 - 0.022 14.8 0.6 0.031 14.4 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGC39232.1 - 0.12 12.1 0.9 6.7 6.4 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Tti2 PF10521.9 EGC39232.1 - 0.13 11.8 1.3 0.16 11.4 1.3 1.1 1 0 0 1 1 1 0 Tti2 family RsgA_GTPase PF03193.16 EGC39232.1 - 0.31 10.9 3.3 3.5 7.5 0.5 2.7 2 1 0 2 2 2 0 RsgA GTPase Glutaminase PF04960.15 EGC39233.1 - 2.8e-30 105.5 0.4 8.8e-30 103.9 0.0 1.9 2 0 0 2 2 2 1 Glutaminase SH3_1 PF00018.28 EGC39233.1 - 4.1e-28 96.7 0.8 3.8e-14 52.0 0.1 2.7 2 0 0 2 2 2 2 SH3 domain SH3_9 PF14604.6 EGC39233.1 - 3.3e-23 81.3 0.9 2.8e-11 43.1 0.0 3.4 3 0 0 3 3 3 2 Variant SH3 domain SH3_2 PF07653.17 EGC39233.1 - 1.9e-22 78.7 0.0 5.1e-12 45.3 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain CS PF04969.16 EGC39233.1 - 1.2e-08 35.8 0.3 4e-08 34.1 0.3 2.0 1 0 0 1 1 1 1 CS domain GalKase_gal_bdg PF10509.9 EGC39234.1 - 7.2e-22 76.7 0.1 1.3e-21 75.8 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.13 EGC39234.1 - 2.2e-14 53.6 0.0 6.3e-14 52.1 0.0 1.8 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.26 EGC39234.1 - 8.5e-10 38.7 0.1 1.6e-09 37.9 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain SRP19 PF01922.17 EGC39235.1 - 1.2e-27 96.7 1.2 1.5e-27 96.4 0.3 1.6 2 0 0 2 2 2 1 SRP19 protein DUF4805 PF16063.5 EGC39235.1 - 0.32 10.3 8.5 0.67 9.2 8.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4805) Joubert PF15392.6 EGC39236.1 - 0.0015 18.3 0.3 0.0019 18.0 0.3 1.1 1 0 0 1 1 1 1 Joubert syndrome-associated DUF4048 PF13257.6 EGC39236.1 - 0.7 9.7 5.1 1 9.2 5.0 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4048) DHHC PF01529.20 EGC39237.1 - 4.8e-29 101.2 8.4 4.8e-29 101.2 8.4 3.0 3 1 0 3 3 3 1 DHHC palmitoyltransferase Ank_2 PF12796.7 EGC39237.1 - 2.6e-08 34.3 0.0 7.4e-08 32.9 0.0 1.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC39237.1 - 3.7e-06 27.4 0.0 8.4e-06 26.2 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.30 EGC39237.1 - 0.00012 22.3 0.1 0.011 16.2 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.6 EGC39237.1 - 0.00013 22.1 0.0 0.12 13.0 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.6 EGC39237.1 - 0.0017 18.6 0.0 0.47 10.9 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Hce2 PF14856.6 EGC39237.1 - 0.062 13.6 0.2 0.14 12.4 0.2 1.6 1 0 0 1 1 1 0 Pathogen effector; putative necrosis-inducing factor Chorion_3 PF05387.11 EGC39237.1 - 0.14 11.8 1.4 0.23 11.1 1.4 1.2 1 0 0 1 1 1 0 Chorion family 3 AIPR PF10592.9 EGC39237.1 - 0.53 9.9 3.9 3.7 7.1 1.6 2.3 2 0 0 2 2 2 0 AIPR protein Glycogen_syn PF05693.13 EGC39239.1 - 1.6e-266 886.0 0.0 2e-266 885.6 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.20 EGC39239.1 - 0.00014 21.4 0.0 0.0018 17.9 0.0 2.4 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.6 EGC39239.1 - 0.0017 18.4 0.0 0.0031 17.5 0.0 1.4 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.11 EGC39239.1 - 0.0019 17.9 0.0 0.0042 16.8 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_1_4 PF13692.6 EGC39239.1 - 0.014 15.8 0.0 0.67 10.4 0.0 2.3 2 0 0 2 2 2 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.6 EGC39239.1 - 0.03 14.8 0.0 0.059 13.8 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain DUF2046 PF09755.9 EGC39239.1 - 0.036 13.3 4.5 0.063 12.5 4.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein H4 (DUF2046) HSP20 PF00011.21 EGC39240.1 - 2.6e-12 46.8 0.0 3.7e-12 46.3 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family ArsA_HSP20 PF17886.1 EGC39240.1 - 0.00022 20.7 0.0 0.00032 20.2 0.0 1.3 1 0 0 1 1 1 1 HSP20-like domain found in ArsA BON PF04972.17 EGC39240.1 - 0.0016 18.7 0.1 1.4 9.3 0.0 2.5 3 0 0 3 3 3 2 BON domain Endotoxin_N PF03945.14 EGC39242.1 - 2.1e-23 83.2 0.0 3.3e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain VRR_NUC PF08774.11 EGC39242.1 - 0.0093 16.0 0.0 0.02 14.9 0.0 1.5 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.25 EGC39243.1 - 7.2e-71 238.6 0.0 7.2e-71 238.6 0.0 4.6 3 1 3 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39243.1 - 2.6e-48 164.6 0.0 2.6e-48 164.6 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase TPR_2 PF07719.17 EGC39244.1 - 0.00013 21.8 3.1 0.011 15.8 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39244.1 - 0.015 15.1 0.0 0.32 10.9 0.0 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39244.1 - 0.38 11.1 5.9 0.69 10.3 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat GnRH PF00446.17 EGC39246.1 - 0.0065 16.7 2.1 2.9 8.5 0.2 2.5 2 0 0 2 2 2 2 Gonadotropin-releasing hormone DUF5514 PF17633.2 EGC39246.1 - 0.0099 16.1 0.8 0.016 15.4 0.8 1.4 1 0 0 1 1 1 1 Family of unknown function (DUF5514) DUF4649 PF15507.6 EGC39247.1 - 0.061 13.3 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) DUF5126 PF17166.4 EGC39247.1 - 0.11 12.3 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF5126) Peptidase_M20 PF01546.28 EGC39248.1 - 1.9e-32 112.6 0.0 3.3e-32 111.9 0.0 1.4 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC39248.1 - 6.1e-19 68.0 0.0 1.3e-18 66.9 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.17 EGC39248.1 - 0.0066 16.2 0.0 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 ATP19 PF11022.8 EGC39249.1 - 0.017 15.4 1.9 0.035 14.5 1.7 1.8 1 1 0 1 1 1 0 ATP synthase subunit K RNA_polI_A14 PF08203.11 EGC39249.1 - 0.051 14.3 1.5 0.063 14.0 1.5 1.2 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF3439 PF11921.8 EGC39251.1 - 4.4 7.3 14.1 15 5.6 14.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myosin_TH1 PF06017.13 EGC39253.1 - 1.3e-38 132.5 8.7 5.3e-36 124.1 5.1 2.4 2 0 0 2 2 2 2 Unconventional myosin tail, actin- and lipid-binding hSac2 PF12456.8 EGC39253.1 - 0.0051 16.5 0.6 0.016 14.9 0.2 2.0 2 0 0 2 2 2 1 Inositol phosphatase Orthopox_F8 PF05886.11 EGC39254.1 - 0.032 14.3 2.7 0.091 12.9 2.7 1.8 1 0 0 1 1 1 0 Orthopoxvirus F8 protein ABC2_membrane PF01061.24 EGC39255.1 - 5.4e-32 110.9 25.2 8.9e-32 110.2 25.2 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC39255.1 - 3.1e-23 82.8 0.7 7.7e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.6 EGC39255.1 - 0.011 15.5 6.8 0.096 12.5 0.0 2.8 2 1 0 3 3 3 0 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC39255.1 - 0.018 14.5 0.1 12 5.2 0.2 3.1 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGC39255.1 - 0.028 14.7 0.2 0.78 10.0 0.1 2.8 3 0 0 3 3 3 0 AAA domain RsgA_GTPase PF03193.16 EGC39255.1 - 0.068 13.1 0.1 0.18 11.7 0.1 1.7 1 0 0 1 1 1 0 RsgA GTPase FtsK_SpoIIIE PF01580.18 EGC39255.1 - 0.083 12.2 0.2 0.083 12.2 0.2 1.6 2 0 0 2 2 2 0 FtsK/SpoIIIE family NACHT PF05729.12 EGC39255.1 - 0.1 12.5 0.3 0.27 11.1 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.6 EGC39255.1 - 0.11 12.2 0.7 0.28 11.0 0.7 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.23 EGC39255.1 - 0.23 11.5 1.7 0.27 11.3 0.1 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase ADK PF00406.22 EGC39255.1 - 0.29 11.2 1.6 0.69 10.0 0.6 2.0 2 0 0 2 2 2 0 Adenylate kinase Pro-kuma_activ PF09286.11 EGC39256.1 - 2.4e-33 115.4 0.5 3.6e-33 114.8 0.5 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Ribosomal_S17 PF00366.20 EGC39257.1 - 1e-19 70.4 0.2 1.8e-19 69.6 0.2 1.4 1 0 0 1 1 1 1 Ribosomal protein S17 APH PF01636.23 EGC39258.1 - 6.4e-14 52.5 0.0 2.5e-13 50.5 0.0 1.8 2 0 0 2 2 2 1 Phosphotransferase enzyme family SWIRM-assoc_3 PF16498.5 EGC39258.1 - 0.13 12.5 0.0 0.4 11.0 0.0 1.8 1 0 0 1 1 1 0 SWIRM-associated domain at the C-terminal VWA_2 PF13519.6 EGC39259.1 - 7.5e-08 33.0 0.7 3.8e-07 30.7 0.0 2.5 2 0 0 2 2 2 1 von Willebrand factor type A domain ubiquitin PF00240.23 EGC39259.1 - 2.2e-07 30.5 0.2 5.8e-07 29.2 0.2 1.8 1 0 0 1 1 1 1 Ubiquitin family Roc PF08477.13 EGC39259.1 - 0.058 13.6 0.0 2.1 8.6 0.1 3.3 1 1 0 2 2 2 0 Ras of Complex, Roc, domain of DAPkinase Dynamin_N PF00350.23 EGC39259.1 - 1.1 9.3 9.4 9.4 6.3 0.0 3.5 3 0 0 3 3 3 0 Dynamin family DUF3530 PF12048.8 EGC39259.1 - 2.9 7.2 5.9 0.16 11.3 0.2 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3530) DUF3439 PF11921.8 EGC39259.1 - 4 7.4 25.0 0.17 11.8 2.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Mito_fiss_reg PF05308.11 EGC39259.1 - 8.8 6.3 12.5 0.067 13.3 1.0 2.9 4 0 0 4 4 4 0 Mitochondrial fission regulator DUF4460 PF14687.6 EGC39260.1 - 2.7e-09 37.0 1.3 2.7e-09 37.0 1.3 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) Myb_DNA-bind_5 PF13873.6 EGC39260.1 - 0.028 14.5 0.4 0.14 12.2 0.2 2.4 2 0 0 2 2 2 0 Myb/SANT-like DNA-binding domain Carot_N PF09150.10 EGC39260.1 - 0.14 12.0 1.2 1.2 8.9 0.3 2.6 2 0 0 2 2 2 0 Orange carotenoid protein, N-terminal ubiquitin PF00240.23 EGC39261.1 - 2.5e-13 49.6 0.0 4.5e-13 48.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC39261.1 - 1e-07 31.7 0.1 1.8e-07 30.8 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.8 EGC39261.1 - 0.0042 17.3 0.3 0.013 15.8 0.1 1.8 2 0 0 2 2 2 1 TUG ubiquitin-like domain DUF2407 PF10302.9 EGC39261.1 - 0.085 13.4 0.0 0.096 13.3 0.0 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC39261.1 - 0.12 12.7 0.0 0.21 12.0 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-like domain Clathrin PF00637.20 EGC39262.1 - 1.1e-196 644.6 59.3 5.4e-33 113.9 0.8 8.7 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_propel PF01394.20 EGC39262.1 - 2.4e-42 141.2 5.0 6.2e-07 29.4 0.2 7.1 7 0 0 7 7 7 6 Clathrin propeller repeat Clathrin_H_link PF13838.6 EGC39262.1 - 2.7e-30 104.1 3.4 5.2e-30 103.2 0.4 3.1 3 0 0 3 3 3 1 Clathrin-H-link Clathrin-link PF09268.10 EGC39262.1 - 2.3e-11 42.8 0.9 2.3e-11 42.8 0.9 2.3 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.28 EGC39262.1 - 0.0059 16.4 4.4 28 4.8 0.1 5.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39262.1 - 0.062 13.4 10.5 24 5.4 0.5 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat P2_N PF18628.1 EGC39262.1 - 0.062 13.0 0.2 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 Viral coat protein P2 N-terminal domain ANAPC3 PF12895.7 EGC39262.1 - 0.16 12.2 3.0 28 5.0 0.0 4.0 3 0 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 Tom37 PF10568.9 EGC39262.1 - 0.46 10.8 6.6 0.27 11.5 0.6 3.2 4 0 0 4 4 4 0 Outer mitochondrial membrane transport complex protein TPR_7 PF13176.6 EGC39262.1 - 1 9.6 9.7 19 5.6 0.1 6.4 8 0 0 8 8 8 0 Tetratricopeptide repeat MIF4G PF02854.19 EGC39264.1 - 5.3e-39 134.0 15.3 1.2e-38 132.9 15.3 1.6 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.17 EGC39264.1 - 1.5e-05 24.9 1.6 0.00021 21.2 0.1 2.5 2 0 0 2 2 2 1 MA3 domain UCH PF00443.29 EGC39265.1 - 2e-44 152.1 7.0 3.3e-44 151.3 7.0 1.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC39265.1 - 9.3e-06 25.4 12.2 0.00015 21.5 12.2 2.3 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase PrmA PF06325.13 EGC39266.1 - 4.1e-09 36.3 0.1 6.6e-09 35.6 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_25 PF13649.6 EGC39266.1 - 8.1e-09 36.1 0.0 1.8e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC39266.1 - 3.3e-07 30.9 0.0 9.2e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC39266.1 - 3.6e-07 29.9 0.2 6.1e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGC39266.1 - 5.7e-06 26.2 0.4 1.7e-05 24.7 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain PRMT5 PF05185.16 EGC39266.1 - 8.9e-06 25.7 0.5 1.4e-05 25.1 0.0 1.6 2 0 0 2 2 2 1 PRMT5 arginine-N-methyltransferase Methyltransf_23 PF13489.6 EGC39266.1 - 9.6e-05 22.3 0.0 0.00027 20.8 0.0 1.7 1 1 1 2 2 2 1 Methyltransferase domain Met_10 PF02475.16 EGC39266.1 - 0.00059 19.6 0.0 0.0009 19.0 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_16 PF10294.9 EGC39266.1 - 0.0044 16.8 0.0 0.0072 16.1 0.0 1.3 1 0 0 1 1 1 1 Lysine methyltransferase TehB PF03848.14 EGC39266.1 - 0.014 14.8 0.5 0.49 9.8 0.1 2.3 2 1 0 2 2 2 0 Tellurite resistance protein TehB Cons_hypoth95 PF03602.15 EGC39266.1 - 0.019 14.6 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_18 PF12847.7 EGC39266.1 - 0.024 14.6 0.0 0.047 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.19 EGC39266.1 - 0.074 13.2 0.1 0.11 12.6 0.1 1.5 1 1 0 1 1 1 0 FtsJ-like methyltransferase Mrx7 PF10906.8 EGC39266.1 - 0.11 12.8 0.0 0.29 11.4 0.0 1.7 1 0 0 1 1 1 0 MIOREX complex component 7 DUF4340 PF14238.6 EGC39266.1 - 0.16 12.0 0.1 0.58 10.2 0.0 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4340) GidB PF02527.15 EGC39266.1 - 0.16 11.3 0.3 0.39 10.0 0.3 1.5 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G PC4 PF02229.16 EGC39267.1 - 7.3e-17 60.7 0.1 7.3e-17 60.7 0.1 1.7 2 0 0 2 2 1 1 Transcriptional Coactivator p15 (PC4) DUF908 PF06012.12 EGC39267.1 - 0.019 14.4 10.3 0.022 14.2 10.3 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF908) PRP38_assoc PF12871.7 EGC39267.1 - 0.069 13.8 11.4 0.093 13.3 11.4 1.2 1 0 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SWIRM-assoc_2 PF16496.5 EGC39267.1 - 0.092 11.6 9.9 0.1 11.4 9.9 1.1 1 0 0 1 1 1 0 SWIRM-associated domain at the N-terminal Sec62 PF03839.16 EGC39267.1 - 0.14 11.6 6.5 0.18 11.3 6.5 1.2 1 0 0 1 1 1 0 Translocation protein Sec62 SpoIIIAH PF12685.7 EGC39267.1 - 0.17 11.7 12.2 0.18 11.6 12.2 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF2052 PF09747.9 EGC39267.1 - 0.19 11.9 9.9 0.26 11.4 9.9 1.2 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) Apt1 PF10351.9 EGC39267.1 - 0.26 10.1 12.2 0.28 10.0 12.2 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Menin PF05053.13 EGC39267.1 - 0.38 9.1 10.3 0.43 8.9 10.3 1.0 1 0 0 1 1 1 0 Menin TFIIF_alpha PF05793.12 EGC39267.1 - 0.45 9.1 20.5 0.49 8.9 20.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Presenilin PF01080.17 EGC39267.1 - 0.6 8.8 9.7 0.59 8.8 9.7 1.1 1 0 0 1 1 1 0 Presenilin CDC45 PF02724.14 EGC39267.1 - 0.81 7.9 14.2 0.9 7.8 14.2 1.0 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EGC39267.1 - 1.1 8.4 7.0 1.1 8.4 7.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter DUF4674 PF15719.5 EGC39267.1 - 1.2 9.2 15.4 1.4 8.9 15.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4674) PBP1_TM PF14812.6 EGC39267.1 - 1.3 9.5 8.6 2.3 8.7 8.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Dsh_C PF12316.8 EGC39267.1 - 1.6 9.1 10.7 1.8 8.9 10.7 1.1 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal CPSF100_C PF13299.6 EGC39267.1 - 1.8 8.7 9.9 2.4 8.3 9.9 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SLC12 PF03522.15 EGC39267.1 - 2.2 7.2 9.1 2.4 7.1 9.1 1.1 1 0 0 1 1 1 0 Solute carrier family 12 Macoilin PF09726.9 EGC39267.1 - 2.2 6.7 12.2 2.3 6.7 12.2 1.0 1 0 0 1 1 1 0 Macoilin family PI3K_1B_p101 PF10486.9 EGC39267.1 - 3 5.5 12.7 3.4 5.3 12.7 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit RNA_pol_Rpc4 PF05132.14 EGC39267.1 - 3 8.2 10.7 4.4 7.7 10.7 1.3 1 0 0 1 1 1 0 RNA polymerase III RPC4 FAM60A PF15396.6 EGC39267.1 - 3.2 7.7 11.9 4 7.4 11.9 1.1 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3c_N PF05470.12 EGC39267.1 - 3.9 5.7 10.4 4.3 5.5 10.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus SSP160 PF06933.11 EGC39267.1 - 5 5.2 10.5 6.2 4.9 10.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF4614 PF15391.6 EGC39267.1 - 6 6.8 15.6 8.2 6.4 15.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4614) Mem_trans PF03547.18 EGC39267.1 - 7.5 4.8 6.3 8.5 4.6 6.3 1.1 1 0 0 1 1 1 0 Membrane transport protein DUF4637 PF15470.6 EGC39267.1 - 7.6 6.2 12.1 10 5.8 12.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) MCM_bind PF09739.9 EGC39267.1 - 7.9 4.8 10.8 8.5 4.7 10.8 1.0 1 0 0 1 1 1 0 Mini-chromosome maintenance replisome factor Folate_carrier PF01770.18 EGC39267.1 - 9.6 4.8 6.6 11 4.6 6.6 1.1 1 0 0 1 1 1 0 Reduced folate carrier PH PF00169.29 EGC39268.1 - 2.3e-14 53.8 0.9 5e-14 52.7 0.9 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.6 EGC39268.1 - 0.069 13.6 12.6 0.02 15.3 7.7 2.6 2 1 0 2 2 2 0 Pleckstrin homology domain PTP_tm PF18861.1 EGC39268.1 - 0.088 12.8 4.7 0.17 11.9 4.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J VPS9 PF02204.18 EGC39269.1 - 1.4e-11 44.5 0.1 1.2e-10 41.5 0.1 2.5 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain NOA36 PF06524.12 EGC39269.1 - 6.1 6.1 15.1 17 4.6 15.1 1.7 1 0 0 1 1 1 0 NOA36 protein Polyketide_cyc2 PF10604.9 EGC39270.1 - 7.1e-07 29.6 0.1 1.3e-06 28.8 0.1 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPD PF14811.6 EGC39271.1 - 1.3e-48 164.3 0.3 2.9e-48 163.2 0.1 1.6 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif DUF2972 PF11186.8 EGC39271.1 - 0.94 9.4 10.5 0.81 9.6 7.5 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2972) TPT PF03151.16 EGC39272.1 - 1e-34 120.3 29.6 1.2e-34 120.1 29.6 1.0 1 0 0 1 1 1 1 Triose-phosphate Transporter family EamA PF00892.20 EGC39272.1 - 4.5e-10 39.8 39.4 3.6e-07 30.4 13.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.11 EGC39272.1 - 1.7e-09 37.4 32.5 2.1e-09 37.0 32.5 1.1 1 0 0 1 1 1 1 UAA transporter family Tnp_P_element_C PF12596.8 EGC39272.1 - 0.13 12.8 0.4 0.29 11.7 0.4 1.5 1 0 0 1 1 1 0 87kDa Transposase Gaa1 PF04114.14 EGC39272.1 - 0.35 9.8 21.4 0.34 9.9 3.4 2.8 1 1 1 2 2 2 0 Gaa1-like, GPI transamidase component ABC2_membrane PF01061.24 EGC39273.1 - 4.1e-36 124.4 26.2 6.8e-36 123.7 26.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.27 EGC39273.1 - 9.2e-30 103.9 0.3 2.1e-29 102.8 0.3 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC39273.1 - 5.8e-06 26.3 0.0 0.086 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system ABC2_membrane_3 PF12698.7 EGC39273.1 - 9.9e-06 24.9 27.2 9.9e-06 24.9 27.2 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein RsgA_GTPase PF03193.16 EGC39273.1 - 4.4e-05 23.4 1.1 0.0001 22.2 1.1 1.6 1 0 0 1 1 1 1 RsgA GTPase AAA_29 PF13555.6 EGC39273.1 - 7.5e-05 22.4 0.2 0.00016 21.4 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain SMC_N PF02463.19 EGC39273.1 - 7.6e-05 22.2 0.2 0.00071 19.1 0.2 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.6 EGC39273.1 - 0.0011 18.6 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC39273.1 - 0.0017 18.8 0.0 0.003 18.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.6 EGC39273.1 - 0.0045 17.5 0.6 0.018 15.6 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGC39273.1 - 0.036 14.3 0.0 0.084 13.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain OppC_N PF12911.7 EGC39273.1 - 0.057 13.4 0.3 0.057 13.4 0.3 2.4 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C IstB_IS21 PF01695.17 EGC39273.1 - 0.078 12.7 0.1 4.1 7.1 0.0 2.3 2 0 0 2 2 2 0 IstB-like ATP binding protein Zeta_toxin PF06414.12 EGC39273.1 - 0.082 12.2 0.0 0.15 11.3 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin NACHT PF05729.12 EGC39273.1 - 0.097 12.6 0.4 0.19 11.6 0.4 1.5 1 0 0 1 1 1 0 NACHT domain DUF3149 PF11346.8 EGC39273.1 - 0.097 12.3 0.2 0.097 12.3 0.2 2.6 2 0 0 2 2 1 0 Protein of unknown function (DUF3149) AAA_30 PF13604.6 EGC39273.1 - 0.13 12.0 0.0 0.19 11.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.6 EGC39273.1 - 0.15 12.5 10.0 1 9.8 0.0 2.5 1 1 1 2 2 2 0 AAA domain DUF4407 PF14362.6 EGC39273.1 - 0.23 10.7 0.9 0.59 9.4 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) PDR_CDR PF06422.12 EGC39273.1 - 2.2 8.3 8.1 0.68 9.9 0.4 2.8 2 0 0 2 2 2 0 CDR ABC transporter DUF87 PF01935.17 EGC39273.1 - 8.8 6.4 8.4 1.9 8.6 0.9 2.3 1 1 1 2 2 2 0 Helicase HerA, central domain Rhodanese PF00581.20 EGC39274.1 - 2.2e-12 47.4 0.3 1e-10 42.1 0.3 2.2 1 1 0 1 1 1 1 Rhodanese-like domain PPR_2 PF13041.6 EGC39275.1 - 1e-16 60.9 8.3 5.7e-10 39.2 0.1 4.8 3 1 2 5 5 5 3 PPR repeat family PPR PF01535.20 EGC39275.1 - 2e-10 40.2 0.1 0.48 10.8 0.0 4.6 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.6 EGC39275.1 - 1.7e-06 28.0 1.3 0.0021 18.1 0.1 2.7 2 1 2 4 4 4 2 Pentatricopeptide repeat domain PPR_long PF17177.4 EGC39275.1 - 2.7e-06 26.9 0.4 3.1e-05 23.4 0.4 2.2 1 1 1 2 2 2 1 Pentacotripeptide-repeat region of PRORP PPR_1 PF12854.7 EGC39275.1 - 0.00032 20.3 0.2 2.8 7.7 0.0 3.6 3 0 0 3 3 3 2 PPR repeat GSAP-16 PF14959.6 EGC39275.1 - 0.054 13.4 0.2 0.33 10.9 0.1 2.3 2 0 0 2 2 2 0 gamma-Secretase-activating protein C-term UDPGT PF00201.18 EGC39275.1 - 0.085 11.6 0.8 2.1 7.0 0.0 2.1 2 0 0 2 2 2 0 UDP-glucoronosyl and UDP-glucosyl transferase PAT1 PF09770.9 EGC39276.1 - 2 6.6 8.7 2.5 6.3 8.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-RING_2 PF13639.6 EGC39277.1 - 1.4e-10 41.4 12.1 2.7e-10 40.4 12.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC39277.1 - 5.2e-07 29.4 11.2 1.2e-06 28.2 11.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC39277.1 - 7.9e-07 28.8 8.6 1.4e-06 28.1 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39277.1 - 2e-06 28.0 7.8 6.4e-06 26.4 7.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC39277.1 - 6e-06 26.0 13.7 1.7e-05 24.6 13.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC39277.1 - 0.00032 20.8 40.3 0.00032 20.8 40.3 2.1 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC39277.1 - 0.0026 17.7 12.4 0.0069 16.3 12.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC39277.1 - 0.01 15.6 8.2 0.034 14.0 8.3 1.8 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC39277.1 - 0.037 14.1 5.4 0.1 12.7 5.4 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGC39277.1 - 0.16 12.0 9.3 0.63 10.1 9.3 2.2 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC39277.1 - 0.27 11.4 13.1 0.69 10.1 13.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC39277.1 - 0.36 10.6 8.3 0.73 9.6 8.3 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_10 PF16685.5 EGC39277.1 - 0.39 10.9 10.1 0.96 9.6 10.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Zn_ribbon_17 PF17120.5 EGC39277.1 - 1.3 8.7 9.3 2.6 7.7 9.3 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type ATP-synt_8 PF00895.20 EGC39277.1 - 9.2 6.8 8.7 0.51 10.8 0.3 3.4 2 1 0 2 2 1 0 ATP synthase protein 8 2_5_RNA_ligase2 PF13563.6 EGC39278.1 - 6.1e-05 23.0 0.0 6.3e-05 22.9 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily F5_F8_type_C PF00754.25 EGC39279.1 - 2.8e-21 76.0 2.0 6.1e-21 74.9 2.0 1.5 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC39279.1 - 1.1e-20 73.6 0.4 1.1e-20 73.6 0.4 1.9 2 1 0 2 2 2 1 H-type lectin domain pXO2-34 PF17362.2 EGC39279.1 - 0.12 12.3 0.1 0.22 11.4 0.1 1.4 1 0 0 1 1 1 0 Family of unknown function DUF3012 PF11216.8 EGC39279.1 - 0.12 12.4 0.1 0.24 11.5 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3012) HSP33 PF01430.19 EGC39280.1 - 6.2e-53 179.9 0.1 1.3e-52 178.9 0.1 1.4 1 0 0 1 1 1 1 Hsp33 protein PLDc PF00614.22 EGC39280.1 - 3.7e-06 26.9 0.7 0.0095 16.1 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif TIG PF01833.24 EGC39281.1 - 1.3e-12 47.6 59.8 4e-05 23.6 1.7 7.3 7 0 0 7 7 7 5 IPT/TIG domain EGF_2 PF07974.13 EGC39281.1 - 0.22 12.0 27.8 0.067 13.6 9.2 3.1 2 0 0 2 2 2 0 EGF-like domain SPX PF03105.19 EGC39281.1 - 1.7 8.4 7.7 2.7 7.8 7.7 1.2 1 0 0 1 1 1 0 SPX domain I-EGF_1 PF18372.1 EGC39281.1 - 2.9 8.1 18.2 3.3 7.9 3.7 3.2 2 0 0 2 2 2 0 Integrin beta epidermal growth factor like domain 1 EB PF01683.18 EGC39281.1 - 5.8 7.3 18.2 13 6.1 5.6 2.6 2 0 0 2 2 2 0 EB module CENP-T_C PF15511.6 EGC39282.1 - 2.1e-08 34.2 0.1 2.6e-08 33.9 0.1 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T histone fold CENP-S PF15630.6 EGC39282.1 - 0.00027 21.3 0.0 0.00076 19.8 0.0 1.7 2 0 0 2 2 2 1 CENP-S protein TAF PF02969.17 EGC39282.1 - 0.00033 20.8 0.0 0.00043 20.4 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ribosomal_L29e PF01779.17 EGC39282.1 - 0.0024 18.1 1.6 0.0094 16.3 1.6 1.9 1 1 0 1 1 1 1 Ribosomal L29e protein family CBFD_NFYB_HMF PF00808.23 EGC39282.1 - 0.0054 17.0 0.0 0.014 15.7 0.0 1.7 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.13 EGC39282.1 - 0.0077 16.2 0.1 0.013 15.5 0.1 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-31kDa PF02291.15 EGC39282.1 - 0.0079 16.3 0.0 0.0084 16.2 0.0 1.2 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit Histone PF00125.24 EGC39282.1 - 0.017 15.5 0.7 0.028 14.8 0.7 1.6 1 1 0 1 1 1 0 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.16 EGC39282.1 - 0.033 14.2 0.0 0.045 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit CRT-like PF08627.10 EGC39283.1 - 5.8e-157 521.9 17.3 6.7e-157 521.7 17.3 1.0 1 0 0 1 1 1 1 CRT-like, chloroquine-resistance transporter-like SLC35F PF06027.12 EGC39283.1 - 4.5e-07 29.7 3.2 4.5e-07 29.7 3.2 2.2 2 0 0 2 2 2 1 Solute carrier family 35 UAA PF08449.11 EGC39283.1 - 0.00088 18.6 6.9 0.00088 18.6 6.9 2.1 2 0 0 2 2 2 1 UAA transporter family EamA PF00892.20 EGC39283.1 - 0.0067 16.6 12.5 0.0067 16.6 12.5 2.8 3 0 0 3 3 3 2 EamA-like transporter family CE2_N PF17996.1 EGC39284.1 - 7.6e-15 54.9 0.0 1.5e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Carbohydrate esterase 2 N-terminal Lipase_GDSL_2 PF13472.6 EGC39284.1 - 1.6e-06 28.7 0.0 2.1e-06 28.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.22 EGC39284.1 - 5.9e-06 26.4 0.0 0.00012 22.1 0.0 2.2 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAGK_acc PF00609.19 EGC39285.1 - 4.2e-50 170.2 0.2 2e-48 164.7 0.2 2.5 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain C1_1 PF00130.22 EGC39285.1 - 5.4e-27 93.4 51.7 7.4e-11 41.8 13.2 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) DAGK_cat PF00781.24 EGC39285.1 - 3.2e-25 88.2 0.0 5.4e-25 87.4 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_2 PF03107.16 EGC39285.1 - 2.7e-05 24.4 34.2 0.051 13.9 5.5 3.5 3 0 0 3 3 3 3 C1 domain SeqA PF03925.13 EGC39285.1 - 0.032 14.2 0.1 0.19 11.7 0.2 2.3 2 1 0 2 2 2 0 SeqA protein C-terminal domain Mito_carr PF00153.27 EGC39286.1 - 3.5e-18 65.3 1.0 1e-06 28.6 0.0 3.6 3 1 0 3 3 3 3 Mitochondrial carrier protein CymA PF16941.5 EGC39286.1 - 0.0024 17.1 1.6 0.0031 16.8 1.6 1.2 1 0 0 1 1 1 1 Putative cyclodextrin porin Chordopox_A33R PF05966.12 EGC39286.1 - 0.0062 15.8 0.2 0.01 15.1 0.2 1.3 1 0 0 1 1 1 1 Chordopoxvirus A33R protein SLAC1 PF03595.17 EGC39287.1 - 0.00084 18.7 0.3 0.001 18.4 0.3 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Tetraspanin PF00335.20 EGC39287.1 - 0.0041 16.9 0.3 0.006 16.3 0.3 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF2207 PF09972.9 EGC39287.1 - 0.12 11.1 0.4 0.16 10.7 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PAT1 PF09770.9 EGC39287.1 - 1.6 6.9 16.2 1.8 6.7 16.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FAM222A PF15258.6 EGC39287.1 - 3.2 6.8 20.3 4.1 6.4 20.3 1.1 1 0 0 1 1 1 0 Protein family of FAM222A FNIP PF05725.12 EGC39288.1 - 3e-102 334.6 86.7 9.3e-18 64.1 1.1 11.4 7 2 6 13 13 13 13 FNIP Repeat DUF1769 PF08588.10 EGC39288.1 - 0.00066 19.8 21.5 2 8.7 0.1 8.3 4 3 5 9 9 9 3 Protein of unknown function (DUF1769) Pkinase PF00069.25 EGC39289.1 - 5.8e-27 94.7 0.2 1.8e-21 76.7 0.1 2.0 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39289.1 - 8.1e-16 58.1 0.0 7.2e-13 48.4 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.6 EGC39289.1 - 5.6e-05 22.6 0.0 6.5e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Pkinase_fungal PF17667.1 EGC39289.1 - 0.012 14.4 0.1 0.016 14.0 0.1 1.2 1 0 0 1 1 1 0 Fungal protein kinase DUF4524 PF15025.6 EGC39289.1 - 0.028 14.2 0.0 0.029 14.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4524) APH PF01636.23 EGC39289.1 - 0.048 13.6 0.0 0.064 13.2 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Methyltransf_12 PF08242.12 EGC39290.1 - 7.1e-10 39.5 0.0 1.2e-09 38.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.12 EGC39290.1 - 2e-09 37.3 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_25 PF13649.6 EGC39290.1 - 2.9e-09 37.5 0.0 4.4e-09 36.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC39290.1 - 3e-08 33.7 0.0 4.2e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC39290.1 - 1.8e-06 28.5 0.0 2.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.12 EGC39290.1 - 0.0023 17.1 0.1 0.0035 16.5 0.1 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.20 EGC39290.1 - 0.0055 15.8 0.0 0.0069 15.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_31 PF13847.6 EGC39290.1 - 0.0088 15.8 0.0 0.016 15.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EGC39290.1 - 0.085 12.6 0.0 0.28 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF938) ELO PF01151.18 EGC39291.1 - 1.8e-50 171.8 27.0 2.1e-50 171.6 27.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SEEK1 PF15357.6 EGC39292.1 - 0.068 13.3 4.4 0.14 12.3 4.4 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 PhoR PF11808.8 EGC39292.1 - 0.11 12.9 0.0 0.21 12.0 0.0 1.3 1 0 0 1 1 1 0 Phosphate regulon sensor protein PhoR zf-C4H2 PF10146.9 EGC39293.1 - 4.5e-08 33.7 27.7 4.5e-08 33.7 27.7 2.2 2 1 0 2 2 2 1 Zinc finger-containing protein DUF349 PF03993.12 EGC39293.1 - 0.26 11.6 13.7 0.25 11.6 1.3 2.7 2 0 0 2 2 2 0 Domain of Unknown Function (DUF349) Cob_adeno_trans PF01923.18 EGC39293.1 - 1.1 9.4 5.0 1.8 8.7 3.7 2.0 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TFIIB PF00382.19 EGC39294.1 - 0.0021 18.1 0.0 0.0056 16.7 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat A2L_zn_ribbon PF08792.10 EGC39294.1 - 0.022 14.4 3.9 0.068 12.9 3.9 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain Uso1_p115_head PF04869.14 EGC39295.1 - 2.9e-42 144.9 3.8 2.9e-42 144.9 3.8 2.7 2 1 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region GAS PF13851.6 EGC39295.1 - 0.048 13.0 46.2 0.3 10.4 24.1 3.7 3 0 0 3 3 3 0 Growth-arrest specific micro-tubule binding SKG6 PF08693.10 EGC39296.1 - 0.0033 16.8 0.1 0.0033 16.8 0.1 1.9 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF485 PF04341.12 EGC39296.1 - 0.042 13.8 1.1 0.18 11.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function, DUF485 TatC PF00902.18 EGC39296.1 - 0.061 13.1 0.5 6.7 6.5 0.1 2.1 2 0 0 2 2 2 0 Sec-independent protein translocase protein (TatC) Dicty_spore_N PF04562.12 EGC39297.1 - 8.4e-22 78.0 26.8 8.4e-22 78.0 26.8 5.2 3 1 2 5 5 5 2 Dictyostelium spore coat protein, N terminus SPX PF03105.19 EGC39297.1 - 0.46 10.4 11.3 0.59 10.0 11.3 1.1 1 0 0 1 1 1 0 SPX domain Metallophos PF00149.28 EGC39298.1 - 1.9e-36 126.5 0.1 4.2e-36 125.4 0.1 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF5378 PF17349.2 EGC39298.1 - 0.0091 15.3 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 1 Family of unknown function (DUF5378) PPP5 PF08321.12 EGC39298.1 - 0.11 12.7 0.0 0.3 11.4 0.0 1.7 1 0 0 1 1 1 0 PPP5 TPR repeat region zinc_ribbon_16 PF17034.5 EGC39299.1 - 1.4e-14 54.3 26.3 1.2e-11 44.9 5.4 3.8 4 0 0 4 4 4 2 Zinc-ribbon like family WD40 PF00400.32 EGC39299.1 - 0.053 14.4 0.2 0.053 14.4 0.2 6.4 7 0 0 7 7 7 0 WD domain, G-beta repeat ubiquitin PF00240.23 EGC39300.1 - 3.7e-34 116.3 0.8 6.4e-34 115.5 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.19 EGC39300.1 - 1.1e-24 86.3 3.0 1.1e-24 86.3 3.0 1.6 2 0 0 2 2 2 1 Ribosomal protein S27a Rad60-SLD PF11976.8 EGC39300.1 - 3.7e-16 58.7 0.7 6.2e-16 58.0 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC39300.1 - 4.6e-05 23.8 0.1 0.0002 21.7 0.1 2.0 1 1 0 1 1 1 1 Ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC39300.1 - 0.0033 17.7 1.4 0.0053 17.1 0.1 1.8 1 1 1 2 2 2 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC39300.1 - 0.0047 17.0 0.2 0.01 15.9 0.2 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TBK1_ULD PF18396.1 EGC39300.1 - 0.0088 15.9 0.0 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain IBR PF01485.21 EGC39300.1 - 0.013 15.7 0.3 0.023 14.9 0.3 1.4 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain Ubiquitin_4 PF18036.1 EGC39300.1 - 0.027 14.5 0.9 6.7 6.8 0.1 2.3 2 0 0 2 2 2 0 Ubiquitin-like domain DUF2407 PF10302.9 EGC39300.1 - 0.029 14.9 0.2 0.038 14.5 0.2 1.3 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain BTB_2 PF02214.22 EGC39301.1 - 6.2e-22 77.8 0.0 1.3e-21 76.7 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB_3 PF16017.5 EGC39301.1 - 4.1e-10 39.7 0.0 7.7e-10 38.8 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain Fis1_TPR_N PF14852.6 EGC39301.1 - 6.6e-05 22.5 0.1 0.00026 20.6 0.0 1.9 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.6 EGC39301.1 - 0.00088 19.3 0.1 0.0021 18.1 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGC39301.1 - 0.0011 19.5 0.0 0.0021 18.5 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC39301.1 - 0.0036 17.5 0.2 0.0067 16.6 0.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 DUF4909 PF16253.5 EGC39301.1 - 0.022 14.6 0.5 3.5 7.5 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4909) CH PF00307.31 EGC39302.1 - 5.9e-43 145.5 1.1 4.8e-20 71.8 0.0 2.9 3 0 0 3 3 3 2 Calponin homology (CH) domain Cortex-I_coil PF09304.10 EGC39302.1 - 1.5e-42 144.2 23.1 1.5e-42 144.2 23.1 3.3 4 0 0 4 4 4 2 Cortexillin I, coiled coil CAMSAP_CH PF11971.8 EGC39302.1 - 0.00011 21.9 0.0 0.029 14.2 0.0 2.7 2 1 0 2 2 2 1 CAMSAP CH domain CH_2 PF06294.11 EGC39302.1 - 0.017 15.2 0.2 0.7 10.0 0.0 2.9 2 0 0 2 2 2 0 CH-like domain in sperm protein TolA_bind_tri PF16331.5 EGC39302.1 - 0.16 12.0 18.3 0.024 14.7 10.5 2.8 2 1 0 2 2 2 0 TolA binding protein trimerisation ERM PF00769.19 EGC39302.1 - 0.18 11.6 32.1 0.034 13.9 13.2 2.2 1 1 1 2 2 2 0 Ezrin/radixin/moesin family Leucyl-specific PF14795.6 EGC39302.1 - 2.2 8.4 4.6 8 6.6 1.2 3.0 2 1 0 2 2 2 0 Leucine-tRNA synthetase-specific domain Macoilin PF09726.9 EGC39302.1 - 3.7 6.0 18.6 0.015 13.8 9.4 1.6 2 0 0 2 2 2 0 Macoilin family Baculo_PEP_C PF04513.12 EGC39302.1 - 8.8 6.4 10.4 1.2 9.1 2.3 2.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SapB_1 PF05184.15 EGC39303.1 - 9.8e-23 79.8 9.4 7.3e-13 48.3 0.4 3.5 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.17 EGC39303.1 - 1.7e-16 60.0 4.5 7.1e-12 45.2 0.9 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 2 DUF3456 PF11938.8 EGC39303.1 - 0.048 14.2 2.8 33 5.0 0.1 3.1 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP PARP PF00644.20 EGC39305.1 - 0.022 14.3 1.5 1.2 8.7 0.8 3.2 2 1 0 2 2 2 0 Poly(ADP-ribose) polymerase catalytic domain Rho_GDI PF02115.17 EGC39306.1 - 2e-19 70.1 0.7 2.2e-19 70.0 0.7 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4402 PF14352.6 EGC39306.1 - 0.11 13.2 0.0 0.15 12.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) PTSIIA_gutA PF03829.13 EGC39306.1 - 0.11 12.4 0.1 0.24 11.3 0.1 1.6 1 0 0 1 1 1 0 PTS system glucitol/sorbitol-specific IIA component DUF4598 PF15370.6 EGC39307.1 - 7.5e-14 52.2 14.9 1.2e-13 51.5 14.4 1.7 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) AAA_6 PF12774.7 EGC39307.1 - 0.098 11.6 0.4 0.14 11.1 0.4 1.2 1 0 0 1 1 1 0 Hydrolytic ATP binding site of dynein motor region Ras PF00071.22 EGC39308.1 - 1.9e-61 206.4 1.1 2.3e-61 206.1 1.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39308.1 - 7.6e-35 119.7 0.4 1.3e-34 119.0 0.4 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39308.1 - 3e-14 52.9 0.2 3.8e-14 52.5 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC39308.1 - 9.3e-07 28.9 0.4 1.5e-06 28.2 0.3 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC39308.1 - 9.5e-06 25.2 0.2 1.6e-05 24.4 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGC39308.1 - 1.8e-05 24.7 0.3 0.074 12.9 0.0 2.3 2 0 0 2 2 2 2 RsgA GTPase ATPase_2 PF01637.18 EGC39308.1 - 0.0013 18.7 1.3 0.12 12.3 1.3 2.1 1 1 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_24 PF13479.6 EGC39308.1 - 0.0022 17.8 0.2 0.006 16.3 0.1 1.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.6 EGC39308.1 - 0.0028 18.1 0.0 0.0053 17.2 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain TniB PF05621.11 EGC39308.1 - 0.014 14.9 0.0 0.032 13.7 0.0 1.7 2 0 0 2 2 2 0 Bacterial TniB protein AAA_22 PF13401.6 EGC39308.1 - 0.02 15.1 0.0 0.31 11.3 0.0 2.3 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGC39308.1 - 0.021 14.9 0.4 2 8.5 0.1 2.5 1 1 1 2 2 2 0 AAA domain Hexokinase_2 PF03727.16 EGC39308.1 - 0.046 13.2 0.1 0.061 12.7 0.1 1.4 1 1 0 1 1 1 0 Hexokinase Septin PF00735.18 EGC39308.1 - 0.06 12.6 0.4 0.096 11.9 0.0 1.5 2 0 0 2 2 2 0 Septin FeoB_N PF02421.18 EGC39308.1 - 0.082 12.4 0.7 0.4 10.2 0.7 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B Slx4 PF09494.10 EGC39308.1 - 0.15 12.0 0.0 9.6 6.2 0.0 2.5 2 1 0 2 2 2 0 Slx4 endonuclease AAA_18 PF13238.6 EGC39308.1 - 0.17 12.5 0.2 4.1 8.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain INSC_LBD PF16748.5 EGC39308.1 - 0.23 11.0 1.0 1.2 8.6 0.1 2.2 2 0 0 2 2 2 0 Inscuteable LGN-binding domain GIT_SHD PF08518.11 EGC39308.1 - 0.28 10.9 1.5 1.3 8.7 0.1 2.3 2 0 0 2 2 2 0 Spa2 homology domain (SHD) of GIT FNIP PF05725.12 EGC39309.1 - 4.2e-25 87.6 36.1 7.5e-07 29.2 1.8 9.0 5 3 3 9 9 9 8 FNIP Repeat Dickkopf_N PF04706.12 EGC39310.1 - 0.0092 16.4 3.3 0.0092 16.4 3.3 5.7 3 1 3 6 6 6 4 Dickkopf N-terminal cysteine-rich region SET PF00856.28 EGC39312.1 - 7.8e-13 49.2 2.5 1.9e-12 47.9 2.2 2.4 2 1 1 3 3 3 2 SET domain zf-MYND PF01753.18 EGC39312.1 - 1e-10 41.5 9.6 1e-10 41.5 9.6 3.2 3 0 0 3 3 3 1 MYND finger IF-2B PF01008.17 EGC39312.1 - 0.11 11.7 0.0 0.2 10.9 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family GCM PF03615.15 EGC39312.1 - 0.19 11.6 9.3 0.23 11.3 0.9 2.6 2 0 0 2 2 2 0 GCM motif protein CLU PF13236.6 EGC39313.1 - 1.4e-49 168.9 0.0 1.4e-49 168.9 0.0 2.6 3 0 0 3 3 3 1 Clustered mitochondria eIF3_p135 PF12807.7 EGC39313.1 - 1.4e-06 28.4 0.0 1.4e-06 28.4 0.0 4.8 5 0 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 eIF_4EBP PF05456.11 EGC39314.1 - 0.62 10.0 3.8 7.7 6.5 0.0 2.3 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DUF4834 PF16118.5 EGC39314.1 - 0.79 10.7 6.2 2.1 9.3 6.2 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) TPR_17 PF13431.6 EGC39315.1 - 0.016 15.5 0.1 0.045 14.1 0.2 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39315.1 - 0.017 15.2 0.3 0.91 9.8 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39315.1 - 0.033 14.0 0.2 0.38 10.7 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FNIP PF05725.12 EGC39316.1 - 9.7e-102 333.0 62.3 3.2e-14 52.8 0.0 11.4 7 2 1 11 11 11 11 FNIP Repeat Ald_deCOase PF11266.8 EGC39316.1 - 0.0019 18.0 0.0 4.3 7.0 0.0 3.8 3 1 1 4 4 4 2 Long-chain fatty aldehyde decarbonylase Phage_min_tail PF05939.13 EGC39316.1 - 0.0039 17.5 0.0 28 5.2 0.0 4.9 4 1 1 5 5 5 1 Phage minor tail protein zf-RING_2 PF13639.6 EGC39317.1 - 1e-12 48.2 7.6 1.5e-12 47.6 7.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC39317.1 - 1.7e-09 37.2 6.1 1.7e-09 37.2 6.1 1.7 2 0 0 2 2 2 1 RING-like zinc finger zf-C3HC4_2 PF13923.6 EGC39317.1 - 2e-08 33.9 6.6 3.4e-08 33.2 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39317.1 - 4.5e-08 32.8 7.1 7.5e-08 32.1 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39317.1 - 3.1e-06 27.4 9.3 3.1e-06 27.4 9.3 2.2 2 1 0 2 2 2 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC39317.1 - 1.5e-05 24.9 2.3 1.5e-05 24.9 2.3 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC39317.1 - 7.3e-05 22.6 4.2 0.00011 22.1 4.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.6 EGC39317.1 - 0.00011 22.0 5.6 0.00017 21.4 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-ANAPC11 PF12861.7 EGC39317.1 - 0.0031 17.5 4.2 0.012 15.6 4.2 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC39317.1 - 0.01 15.4 5.5 0.018 14.7 5.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RINGv PF12906.7 EGC39317.1 - 0.19 11.9 5.8 0.48 10.6 5.8 1.6 1 1 0 1 1 1 0 RING-variant domain Prok-RING_4 PF14447.6 EGC39317.1 - 0.35 10.8 5.5 0.79 9.6 5.5 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FANCL_C PF11793.8 EGC39317.1 - 0.65 10.2 7.7 0.15 12.2 2.7 2.3 1 1 1 2 2 2 0 FANCL C-terminal domain Zf_RING PF16744.5 EGC39317.1 - 0.88 9.7 5.9 2.2 8.5 5.8 1.7 1 1 0 1 1 1 0 KIAA1045 RING finger zinc_ribbon_16 PF17034.5 EGC39317.1 - 7.6 6.8 10.0 0.71 10.1 4.1 2.2 2 1 0 2 2 2 0 Zinc-ribbon like family zf-C3H2C3 PF17122.5 EGC39317.1 - 9 6.4 9.4 2.1 8.4 5.4 2.0 2 1 0 2 2 2 0 Zinc-finger FNIP PF05725.12 EGC39318.1 - 2.1e-78 258.2 38.9 7.9e-14 51.6 0.1 9.0 4 2 3 9 9 9 9 FNIP Repeat BCAS2 PF05700.11 EGC39319.1 - 3.8e-62 209.7 14.3 4.4e-62 209.4 14.3 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MaoC_dehydratas PF01575.19 EGC39320.1 - 2.3e-21 75.6 0.0 6.2e-21 74.2 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SET PF00856.28 EGC39320.1 - 3e-16 60.3 0.8 9.9e-16 58.6 0.1 2.3 2 1 0 2 2 2 1 SET domain TPR_1 PF00515.28 EGC39320.1 - 2.7e-09 36.5 0.2 0.0073 16.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39320.1 - 2.1e-06 27.5 0.1 0.0095 16.1 0.0 3.1 3 0 0 3 3 2 2 Tetratricopeptide repeat MaoC_dehydrat_N PF13452.6 EGC39320.1 - 5.4e-06 26.6 0.0 1.1e-05 25.6 0.0 1.5 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TPR_2 PF07719.17 EGC39320.1 - 1.8e-05 24.5 0.1 0.064 13.4 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.6 EGC39320.1 - 3.1e-05 24.2 0.1 0.00017 21.8 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.6 EGC39320.1 - 0.0024 18.3 0.0 0.0052 17.3 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.18 EGC39320.1 - 0.016 15.3 1.1 0.016 15.3 1.1 2.3 3 0 0 3 3 2 0 MYND finger TPR_9 PF13371.6 EGC39320.1 - 0.018 15.2 0.0 0.79 9.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_20 PF14561.6 EGC39320.1 - 0.019 15.3 0.1 5.2 7.5 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_21 PF09976.9 EGC39320.1 - 0.026 14.2 0.0 0.045 13.5 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat-like domain Pox_D2 PF04701.13 EGC39320.1 - 0.03 14.5 0.7 0.066 13.4 0.2 1.8 2 0 0 2 2 1 0 Pox virus D2 protein TPR_7 PF13176.6 EGC39320.1 - 0.037 14.0 0.0 2.5 8.4 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat zf-C6H2 PF15801.5 EGC39320.1 - 0.56 10.5 8.0 0.14 12.5 1.2 2.6 2 0 0 2 2 2 0 zf-MYND-like zinc finger, mRNA-binding Pkinase_Tyr PF07714.17 EGC39321.1 - 3.4e-48 164.2 0.0 5.5e-48 163.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC39321.1 - 3.8e-43 147.7 0.0 7.8e-43 146.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.7 EGC39321.1 - 4.5e-35 120.1 12.1 8.2e-13 48.8 0.1 3.3 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC39321.1 - 5.5e-28 97.0 3.9 3.6e-06 27.4 0.0 6.6 3 2 4 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.6 EGC39321.1 - 6.5e-23 80.5 7.1 3.3e-08 33.6 0.0 4.8 3 1 3 6 6 5 5 Ankyrin repeats (many copies) Ank PF00023.30 EGC39321.1 - 1.1e-22 79.4 1.6 0.0025 18.2 0.1 5.9 6 0 0 6 6 5 5 Ankyrin repeat Ank_3 PF13606.6 EGC39321.1 - 1.3e-19 68.2 1.9 0.023 15.2 0.0 6.6 7 0 0 7 7 7 4 Ankyrin repeat SAM_1 PF00536.30 EGC39321.1 - 7e-12 45.6 0.3 1.9e-11 44.3 0.3 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC39321.1 - 1.3e-05 25.2 0.2 3.3e-05 23.9 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) GLYCAM-1 PF05242.11 EGC39321.1 - 0.13 12.4 1.4 0.29 11.3 1.4 1.5 1 0 0 1 1 1 0 Glycosylation-dependent cell adhesion molecule 1 (GlyCAM-1) DUF3235 PF11574.8 EGC39321.1 - 0.32 11.9 0.0 0.32 11.9 0.0 1.8 2 0 0 2 2 1 0 Protein of unknown function (DUF3235) CBM49 PF09478.10 EGC39322.1 - 7e-12 45.5 0.2 1.1e-11 44.9 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 SH3_10 PF17902.1 EGC39322.1 - 0.011 15.8 0.0 0.019 15.0 0.0 1.4 1 1 0 1 1 1 0 SH3 domain FNIP PF05725.12 EGC39323.1 - 2.3e-79 261.3 47.2 6.4e-14 51.8 0.4 8.7 5 2 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 EGC39323.1 - 0.00044 20.4 8.2 4.3 7.6 0.1 6.3 6 2 1 7 7 7 2 Protein of unknown function (DUF1769) DUF4321 PF14209.6 EGC39323.1 - 3.4 7.6 5.1 9.6 6.1 0.6 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF4321) DEAD PF00270.29 EGC39324.1 - 5.2e-12 45.9 0.0 1.9e-11 44.1 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC39324.1 - 3.4e-11 43.5 1.1 3.7e-10 40.1 0.1 3.0 2 1 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.6 EGC39324.1 - 5.9e-05 23.6 0.0 0.00015 22.3 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.6 EGC39324.1 - 0.0073 16.5 0.0 0.022 15.0 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) CBF PF03914.17 EGC39325.1 - 2.6e-33 115.4 0.1 2.6e-33 115.4 0.1 4.5 4 2 0 4 4 4 1 CBF/Mak21 family Cnd1 PF12717.7 EGC39325.1 - 0.022 14.8 5.5 0.061 13.4 0.8 2.7 2 0 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Chordopox_E11 PF06138.12 EGC39325.1 - 0.039 14.3 0.0 0.12 12.8 0.0 1.7 1 0 0 1 1 1 0 Chordopoxvirus E11 protein Ndc1_Nup PF09531.10 EGC39325.1 - 0.64 8.6 12.4 1.8 7.2 12.4 1.8 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup CLTH PF10607.9 EGC39326.1 - 5.2e-37 127.0 2.3 7e-37 126.6 2.3 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.11 EGC39326.1 - 1.7e-09 37.3 1.1 3.3e-09 36.3 0.2 2.0 2 0 0 2 2 2 1 LisH Thymidylate_kin PF02223.17 EGC39326.1 - 0.0061 16.3 0.1 0.0082 15.8 0.1 1.3 1 0 0 1 1 1 1 Thymidylate kinase TINF2_N PF14973.6 EGC39326.1 - 0.012 16.0 3.4 0.038 14.4 0.2 2.8 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Syntaxin-6_N PF09177.11 EGC39326.1 - 0.28 11.7 4.1 0.22 12.1 0.5 2.5 1 1 2 3 3 3 0 Syntaxin 6, N-terminal RNA_pol_Rpb5_C PF01191.19 EGC39326.1 - 0.7 9.8 3.7 15 5.5 0.1 3.0 3 0 0 3 3 3 0 RNA polymerase Rpb5, C-terminal domain PhaP_Bmeg PF09602.10 EGC39327.1 - 0.0021 18.0 4.3 0.003 17.5 4.3 1.2 1 0 0 1 1 1 1 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) SUIM_assoc PF16619.5 EGC39327.1 - 0.082 13.0 5.7 0.14 12.2 5.7 1.4 1 0 0 1 1 1 0 Unstructured region C-term to UIM in Ataxin3 DUF4175 PF13779.6 EGC39327.1 - 0.18 9.6 3.2 0.23 9.3 3.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Herpes_gE PF02480.16 EGC39328.1 - 0.056 12.2 0.1 4.1 6.0 0.0 2.2 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E zf-CRD PF17979.1 EGC39329.1 - 2.1e-32 112.4 3.7 2.1e-32 112.4 3.7 3.7 4 0 0 4 4 4 1 Cysteine rich domain with multizinc binding regions FHA PF00498.26 EGC39329.1 - 6.6e-18 64.8 0.2 1.6e-17 63.6 0.2 1.7 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC39329.1 - 6.6e-07 29.6 0.0 1.6e-06 28.3 0.0 1.6 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain zf-C3HC4_3 PF13920.6 EGC39329.1 - 4.6e-05 23.2 13.3 4.6e-05 23.2 13.3 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39329.1 - 0.00024 21.4 16.6 0.00024 21.4 16.6 3.3 2 1 0 2 2 1 1 Ring finger domain zf-CCHH PF10283.9 EGC39329.1 - 0.00027 20.9 4.0 0.00082 19.3 4.0 1.9 1 0 0 1 1 1 1 PBZ domain zf-C3HC4_2 PF13923.6 EGC39329.1 - 0.00034 20.4 16.3 0.00034 20.4 16.3 3.4 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39329.1 - 0.0025 17.6 16.4 0.0025 17.6 16.4 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C2H2_9 PF16293.5 EGC39329.1 - 0.018 14.9 0.2 4.8 7.1 0.0 3.0 2 0 0 2 2 2 0 C2H2 type zinc-finger (1 copy) zf-RING_6 PF14835.6 EGC39329.1 - 0.62 10.0 11.5 0.97 9.3 7.6 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Lin-8 PF03353.15 EGC39329.1 - 1.3 8.5 23.9 0.044 13.4 15.6 2.0 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Zip PF02535.22 EGC39329.1 - 1.9 7.6 4.3 2.5 7.2 4.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter TFIIA PF03153.13 EGC39331.1 - 0.068 13.2 32.0 0.087 12.8 32.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SRP-alpha_N PF04086.13 EGC39331.1 - 0.53 10.2 35.2 0.62 9.9 35.2 1.0 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal SelP_N PF04592.14 EGC39331.1 - 3.6 6.9 26.6 0.92 8.9 12.2 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region Ndc1_Nup PF09531.10 EGC39331.1 - 9.7 4.7 18.7 11 4.5 18.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Palm_thioest PF02089.15 EGC39332.1 - 5.8e-12 46.0 0.0 7.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.14 EGC39332.1 - 3.3e-08 33.3 0.2 5.9e-08 32.5 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) PGAP1 PF07819.13 EGC39332.1 - 2.2e-07 30.9 0.1 3.7e-07 30.1 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein LCAT PF02450.15 EGC39332.1 - 0.00026 20.3 0.0 0.00036 19.8 0.0 1.3 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_1 PF00561.20 EGC39332.1 - 0.00049 19.8 0.0 0.0011 18.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.11 EGC39332.1 - 0.0007 19.0 0.1 0.0028 17.0 0.0 1.9 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.12 EGC39332.1 - 0.0017 17.9 0.1 0.0027 17.3 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Hydrolase_4 PF12146.8 EGC39332.1 - 0.011 15.0 0.0 0.016 14.5 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Thioesterase PF00975.20 EGC39332.1 - 0.029 14.5 0.0 0.036 14.2 0.0 1.2 1 0 0 1 1 1 0 Thioesterase domain PRANC PF09372.10 EGC39332.1 - 0.038 14.3 2.5 1.7 9.0 0.0 2.9 3 0 0 3 3 3 0 PRANC domain TRPM_tetra PF16519.5 EGC39332.1 - 0.071 13.2 0.1 0.26 11.4 0.1 1.9 1 1 0 1 1 1 0 Tetramerisation domain of TRPM Peptidase_S66 PF02016.15 EGC39332.1 - 0.082 13.0 0.1 3.2 7.9 0.0 2.2 1 1 1 2 2 2 0 LD-carboxypeptidase N-terminal domain Abhydrolase_6 PF12697.7 EGC39332.1 - 0.1 13.2 0.0 0.14 12.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family DEAD PF00270.29 EGC39333.1 - 1.3e-51 174.9 0.0 2.7e-51 173.8 0.0 1.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC39333.1 - 6.7e-30 103.7 0.2 4.4e-28 97.9 0.1 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC39333.1 - 2.8e-06 27.5 0.0 1.4e-05 25.2 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit ERCC3_RAD25_C PF16203.5 EGC39333.1 - 0.027 13.7 0.0 0.043 13.0 0.0 1.2 1 0 0 1 1 1 0 ERCC3/RAD25/XPB C-terminal helicase WD40 PF00400.32 EGC39334.1 - 1.6e-37 126.8 46.1 3.6e-07 30.8 0.3 12.1 13 0 0 13 13 11 8 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC39334.1 - 7.7e-19 67.8 4.6 0.00011 22.4 0.0 6.2 5 2 2 7 7 6 3 Anaphase-promoting complex subunit 4 WD40 domain DUF4062 PF13271.6 EGC39334.1 - 3.8e-16 59.2 0.0 1.1e-15 57.7 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.6 EGC39334.1 - 2.9e-10 40.8 0.0 1.1e-09 38.8 0.0 2.0 1 1 0 1 1 1 1 AAA ATPase domain APAF1_C PF17908.1 EGC39334.1 - 1.4e-06 28.3 0.5 1.6e-05 24.9 0.5 2.7 1 1 0 1 1 1 1 APAF-1 helical domain AAA_22 PF13401.6 EGC39334.1 - 1.7e-06 28.3 0.0 6.3e-06 26.5 0.0 1.9 1 0 0 1 1 1 1 AAA domain NACHT PF05729.12 EGC39334.1 - 1.6e-05 24.9 0.0 4.8e-05 23.3 0.0 2.0 1 0 0 1 1 1 1 NACHT domain ATPase_2 PF01637.18 EGC39334.1 - 1.8e-05 24.8 0.2 1.8e-05 24.8 0.2 2.6 3 0 0 3 3 2 1 ATPase domain predominantly from Archaea eIF2A PF08662.11 EGC39334.1 - 3e-05 24.0 6.7 0.31 10.9 0.0 3.9 2 1 1 3 3 3 2 Eukaryotic translation initiation factor eIF2A AAA PF00004.29 EGC39334.1 - 3.1e-05 24.4 0.0 0.0002 21.8 0.0 2.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) KAP_NTPase PF07693.14 EGC39334.1 - 0.00011 21.6 3.6 0.15 11.3 0.2 2.6 1 1 1 2 2 2 2 KAP family P-loop domain Ish1 PF10281.9 EGC39334.1 - 0.00018 21.8 0.3 0.00069 19.9 0.3 2.2 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein NB-ARC PF00931.22 EGC39334.1 - 0.00073 18.8 0.2 0.0017 17.6 0.2 1.6 1 0 0 1 1 1 1 NB-ARC domain BBS2_Mid PF14783.6 EGC39334.1 - 0.0011 19.0 0.1 7.7 6.6 0.0 4.4 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region AAA_30 PF13604.6 EGC39334.1 - 0.007 16.1 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain Cytochrom_D1 PF02239.16 EGC39334.1 - 0.012 14.2 0.8 2.3 6.7 0.0 3.4 3 1 1 4 4 4 0 Cytochrome D1 heme domain AAA_assoc_C PF09821.9 EGC39334.1 - 0.1 13.2 0.0 0.49 10.9 0.0 2.2 1 0 0 1 1 1 0 C-terminal AAA-associated domain AROS PF15684.5 EGC39334.1 - 0.41 11.2 7.3 1.1 9.8 6.9 1.9 2 0 0 2 2 1 0 Active regulator of SIRT1, or 40S ribosomal protein S19-binding 1 FNIP PF05725.12 EGC39335.1 - 2.6e-151 491.6 65.9 1.5e-15 57.1 0.5 9.5 2 1 9 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.13 EGC39335.1 - 1.4e-06 28.7 0.0 13 6.3 0.0 7.2 2 2 5 9 9 9 1 Phage minor tail protein MCM_OB PF17207.3 EGC39335.1 - 0.00066 19.5 0.1 84 3.0 0.0 6.1 3 2 3 8 8 8 0 MCM OB domain LRR_5 PF13306.6 EGC39335.1 - 0.01 15.8 1.0 0.64 10.0 0.0 3.7 2 2 2 4 4 4 2 BspA type Leucine rich repeat region (6 copies) HTH_ABP1_N PF18107.1 EGC39335.1 - 0.21 11.3 0.0 1.7e+02 2.0 0.0 5.0 7 0 0 7 7 7 0 Fission yeast centromere protein N-terminal domain FNIP PF05725.12 EGC39336.1 - 3.6e-181 587.2 69.1 2.3e-15 56.5 0.2 14.4 10 3 7 17 17 17 16 FNIP Repeat LRR_5 PF13306.6 EGC39336.1 - 0.019 15.0 1.7 3.1 7.8 0.1 4.6 3 2 0 3 3 3 0 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC39337.1 - 3.2e-31 107.2 7.4 3.4e-15 55.9 0.2 3.0 1 1 0 3 3 3 3 FNIP Repeat FNIP PF05725.12 EGC39338.1 - 1.7e-153 498.6 55.2 8.3e-16 57.9 0.2 12.3 12 0 0 12 12 12 12 FNIP Repeat tRNA-synt_1 PF00133.22 EGC39340.1 - 5e-178 593.1 1.0 6.9e-178 592.7 1.0 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC39340.1 - 7.2e-25 87.7 0.6 1.9e-24 86.4 0.6 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.11 EGC39340.1 - 2.6e-22 79.2 0.1 4.9e-14 51.9 0.0 3.7 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.6 EGC39340.1 - 0.00063 19.3 0.0 0.0047 16.5 0.0 2.3 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.19 EGC39340.1 - 0.0021 17.4 0.2 2.8 7.2 0.0 3.0 3 1 0 3 3 3 2 tRNA synthetases class I (C) catalytic domain RNA_binding PF01877.17 EGC39340.1 - 0.008 16.4 0.2 0.027 14.8 0.2 1.9 1 0 0 1 1 1 1 RNA binding DUF327 PF03885.13 EGC39340.1 - 0.016 15.2 0.4 0.051 13.5 0.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF327) zf-FPG_IleRS PF06827.14 EGC39340.1 - 0.041 13.7 0.9 0.086 12.7 0.9 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS TnpV PF14198.6 EGC39340.1 - 0.087 12.8 0.1 0.36 10.8 0.1 2.0 1 0 0 1 1 1 0 Transposon-encoded protein TnpV MFS_1 PF07690.16 EGC39341.1 - 6.4e-27 94.4 35.5 6.7e-27 94.3 28.9 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.6 EGC39341.1 - 1.4e-12 46.9 17.5 2.6e-12 46.1 17.5 1.3 1 0 0 1 1 1 1 MFS/sugar transport protein Sugar_tr PF00083.24 EGC39341.1 - 2.6e-08 33.2 16.6 4.7e-05 22.4 1.1 2.1 2 0 0 2 2 2 2 Sugar (and other) transporter DUF1774 PF08611.10 EGC39341.1 - 1.7 9.0 5.5 0.98 9.8 0.1 2.9 2 1 1 3 3 3 0 Fungal protein of unknown function (DUF1774) FNIP PF05725.12 EGC39342.1 - 4e-141 459.0 37.9 1.7e-15 56.9 0.1 11.5 5 3 2 11 11 11 11 FNIP Repeat Phage_min_tail PF05939.13 EGC39342.1 - 0.017 15.5 0.0 92 3.5 0.0 5.6 5 2 1 6 6 6 0 Phage minor tail protein Peptidase_S78 PF04586.17 EGC39342.1 - 0.12 12.5 0.0 59 3.8 0.0 4.7 2 2 1 4 4 4 0 Caudovirus prohead serine protease SSURE PF11966.8 EGC39342.1 - 0.29 10.9 13.3 80 3.1 0.1 7.4 6 5 3 9 9 9 0 Fibronectin-binding repeat IML1 PF12257.8 EGC39343.1 - 2.5e-116 387.8 0.6 2.5e-116 387.8 0.6 2.1 2 0 0 2 2 2 1 Vacuolar membrane-associated protein Iml1 DEP PF00610.21 EGC39343.1 - 1.1e-17 63.9 0.0 2.5e-17 62.7 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF4522 PF15022.6 EGC39343.1 - 0.064 13.5 0.1 0.18 12.1 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF4522) Trypan_PARP PF05887.11 EGC39343.1 - 1.5 8.8 5.0 0.51 10.3 0.9 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Dimer_Tnp_hAT PF05699.14 EGC39344.1 - 3.2e-16 58.9 0.5 4.8e-16 58.3 0.5 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ApoLp-III PF07464.11 EGC39344.1 - 0.092 12.8 0.2 0.11 12.5 0.2 1.3 1 0 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) Peptidase_M24 PF00557.24 EGC39345.1 - 1.1e-20 74.2 0.2 1.7e-20 73.6 0.2 1.5 1 1 0 1 1 1 1 Metallopeptidase family M24 DUF1289 PF06945.13 EGC39346.1 - 3.8e-20 71.4 1.9 4.7e-20 71.1 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) FeoB_N PF02421.18 EGC39346.1 - 0.13 11.8 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 Ferrous iron transport protein B Acetyltransf_2 PF00797.17 EGC39347.1 - 0.0036 17.1 0.1 0.0043 16.9 0.1 1.3 1 0 0 1 1 1 1 N-acetyltransferase GTP_EFTU PF00009.27 EGC39348.1 - 8.7e-19 67.8 0.0 1.7e-18 66.9 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.25 EGC39348.1 - 9.4e-11 42.0 3.5 2.3e-10 40.7 3.5 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D3 PF03143.17 EGC39348.1 - 7.6e-05 23.0 0.1 7.6e-05 23.0 0.1 2.3 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain MMR_HSR1 PF01926.23 EGC39348.1 - 0.0021 18.1 1.9 0.0036 17.4 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase Arf PF00025.21 EGC39348.1 - 0.025 14.1 1.4 6.1 6.3 0.0 3.6 3 0 0 3 3 3 0 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC39348.1 - 0.076 12.8 0.0 75 3.0 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Band_7 PF01145.25 EGC39349.1 - 7.6e-26 91.2 1.0 3.1e-25 89.2 0.8 2.0 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF1822 PF08852.11 EGC39349.1 - 0.0024 17.0 1.4 0.0035 16.4 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) DivIVA PF05103.13 EGC39349.1 - 0.39 10.8 7.8 0.71 10.0 7.8 1.4 1 0 0 1 1 1 0 DivIVA protein Hist_deacetyl PF00850.19 EGC39350.1 - 1.5e-93 313.7 0.1 6.3e-93 311.6 0.0 2.1 2 0 0 2 2 2 1 Histone deacetylase domain Zn_Tnp_IS1 PF03811.13 EGC39350.1 - 0.0024 17.5 3.2 0.0049 16.6 3.2 1.5 1 0 0 1 1 1 1 InsA N-terminal domain FNIP PF05725.12 EGC39351.1 - 1.1e-147 480.1 40.7 7.9e-15 54.7 0.0 11.2 9 1 1 11 11 11 11 FNIP Repeat Peptidase_S78 PF04586.17 EGC39351.1 - 4.6e-05 23.7 0.0 38 4.4 0.0 5.9 3 2 3 7 7 7 3 Caudovirus prohead serine protease SSURE PF11966.8 EGC39351.1 - 0.061 13.1 14.5 73 3.2 0.0 8.1 3 2 4 10 10 10 0 Fibronectin-binding repeat zf-met PF12874.7 EGC39352.1 - 4.2e-05 23.8 1.7 0.00012 22.3 1.7 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.8 EGC39352.1 - 9.3e-05 22.6 1.0 0.00022 21.4 1.0 1.7 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding O_Spanin_T7 PF17531.2 EGC39353.1 - 0.098 12.7 0.2 0.15 12.1 0.2 1.3 1 0 0 1 1 1 0 outer-membrane spanin sub-unit zf-RING_2 PF13639.6 EGC39354.1 - 1.6e-09 38.0 10.3 2.7e-09 37.2 10.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39354.1 - 4.1e-08 32.9 8.5 7e-08 32.2 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39354.1 - 8e-08 32.0 9.7 2.2e-07 30.6 9.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39354.1 - 2.5e-07 30.4 8.4 4.3e-07 29.7 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39354.1 - 7.5e-07 29.3 7.0 1.9e-06 28.0 7.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC39354.1 - 0.00038 20.4 4.8 0.00085 19.3 4.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC39354.1 - 0.0034 17.5 8.9 0.0099 16.0 8.3 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.6 EGC39354.1 - 0.056 13.4 10.4 0.11 12.4 10.4 1.6 1 0 0 1 1 1 0 zinc-RING finger domain DZR PF12773.7 EGC39354.1 - 0.095 12.7 7.6 0.31 11.1 7.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.6 EGC39354.1 - 0.22 11.3 8.0 0.78 9.6 8.0 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC39354.1 - 0.29 11.3 4.6 0.72 10.0 4.6 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 DUF3021 PF11457.8 EGC39354.1 - 1.3 9.4 7.3 2.1 8.7 7.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3021) Zn_ribbon_17 PF17120.5 EGC39354.1 - 2.4 7.8 8.7 4.2 7.1 8.7 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Transglut_core PF01841.19 EGC39355.1 - 1.8e-13 50.9 0.0 9.7e-08 32.5 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase-like superfamily SOBP PF15279.6 EGC39355.1 - 0.00037 21.2 28.7 0.00037 21.2 28.7 3.7 4 0 0 4 4 4 1 Sine oculis-binding protein PB1 PF00564.24 EGC39356.1 - 0.14 12.1 0.0 0.61 10.1 0.0 2.0 2 0 0 2 2 2 0 PB1 domain PH PF00169.29 EGC39357.1 - 2.6e-16 60.0 0.4 2.6e-16 60.0 0.4 2.5 1 1 0 2 2 2 1 PH domain PH_8 PF15409.6 EGC39357.1 - 2.2e-05 24.7 0.2 6.2e-05 23.2 0.2 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.6 EGC39357.1 - 0.0003 21.2 2.4 0.0003 21.2 2.4 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.6 EGC39357.1 - 0.0029 17.9 0.0 0.0068 16.7 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.6 EGC39357.1 - 0.036 14.4 1.0 3.1 8.2 0.2 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain PH_16 PF17838.1 EGC39357.1 - 0.045 13.6 0.1 0.13 12.1 0.0 1.8 2 0 0 2 2 2 0 PH domain PH_10 PF15411.6 EGC39357.1 - 0.068 13.4 1.0 0.12 12.7 0.1 1.9 2 0 0 2 2 2 0 Pleckstrin homology domain Asp PF00026.23 EGC39358.1 - 2.4e-15 56.8 0.0 5.7e-15 55.5 0.0 1.5 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.6 EGC39358.1 - 3.3e-13 49.7 0.0 5.9e-13 48.9 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.6 EGC39358.1 - 0.00017 21.8 0.0 0.00032 21.0 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal ETRAMP PF09716.10 EGC39358.1 - 0.06 13.4 0.1 0.11 12.5 0.1 1.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) PPIP5K2_N PF18086.1 EGC39359.1 - 0.67 10.2 10.1 0.084 13.0 0.6 3.9 4 0 0 4 4 4 0 Diphosphoinositol pentakisphosphate kinase 2 N-terminal domain SLAC1 PF03595.17 EGC39361.1 - 0.00038 19.8 2.3 0.00049 19.4 2.3 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Pex14_N PF04695.13 EGC39361.1 - 0.0076 16.9 3.3 0.0078 16.9 3.3 1.2 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region PepSY_TM PF03929.16 EGC39361.1 - 0.017 14.8 2.9 0.02 14.6 2.4 1.4 1 1 0 1 1 1 0 PepSY-associated TM region O-antigen_lig PF13425.6 EGC39361.1 - 0.019 13.8 0.8 0.021 13.6 0.5 1.2 1 1 0 1 1 1 0 O-antigen ligase like membrane protein DUF1461 PF07314.11 EGC39361.1 - 0.024 14.5 0.1 0.029 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1461) Tetraspanin PF00335.20 EGC39361.1 - 0.038 13.7 0.4 0.049 13.3 0.4 1.1 1 0 0 1 1 1 0 Tetraspanin family MgtE PF01769.16 EGC39361.1 - 0.049 14.0 2.7 0.058 13.8 2.7 1.1 1 0 0 1 1 1 0 Divalent cation transporter Frag1 PF10277.9 EGC39361.1 - 0.25 10.8 6.6 0.33 10.5 6.6 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family DUF2076 PF09849.9 EGC39361.1 - 0.89 9.6 14.5 1 9.4 14.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FNIP PF05725.12 EGC39362.1 - 5e-71 234.6 67.0 5.2e-10 39.3 1.2 10.0 4 2 8 12 12 12 12 FNIP Repeat DarA_C PF18789.1 EGC39362.1 - 0.33 11.3 1.5 4.4 7.7 0.0 3.6 5 0 0 5 5 5 0 Defence against restriction A C-terminal IBV_3C PF03620.13 EGC39363.1 - 0.027 14.9 2.3 0.037 14.5 1.9 1.4 1 1 0 1 1 1 0 IBV 3C protein Spore_III_AE PF09546.10 EGC39363.1 - 0.049 12.8 1.6 0.06 12.6 1.6 1.2 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) FNIP PF05725.12 EGC39364.1 - 2.4e-96 315.7 31.1 6.6e-15 55.0 0.2 7.2 5 1 2 8 8 8 8 FNIP Repeat MCM_OB PF17207.3 EGC39364.1 - 0.0077 16.1 0.0 44 3.9 0.0 5.3 3 2 3 7 7 7 1 MCM OB domain SSURE PF11966.8 EGC39364.1 - 0.47 10.2 3.0 20 5.1 0.0 4.0 2 1 2 4 4 4 0 Fibronectin-binding repeat DUF4449 PF14613.6 EGC39365.1 - 0.00064 19.9 3.0 0.00064 19.9 3.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) LBP_BPI_CETP PF01273.25 EGC39365.1 - 0.037 13.6 8.9 0.0091 15.6 4.4 2.3 2 0 0 2 2 2 0 LBP / BPI / CETP family, N-terminal domain Annexin PF00191.20 EGC39365.1 - 0.062 13.4 0.4 0.21 11.7 0.4 1.9 1 0 0 1 1 1 0 Annexin LPD5 PF18799.1 EGC39365.1 - 4.3 7.8 10.0 0.2 12.0 1.1 3.2 3 0 0 3 3 3 0 Large polyvalent protein-associated domain 5 FNIP PF05725.12 EGC39367.1 - 2e-110 360.7 31.5 2.6e-15 56.3 0.6 7.6 2 2 5 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.13 EGC39367.1 - 0.012 16.0 0.0 64 4.0 0.0 4.8 2 1 3 6 6 6 0 Phage minor tail protein LRR_1 PF00560.33 EGC39367.1 - 0.17 12.6 6.5 1.9e+02 3.3 0.0 6.2 4 2 2 6 6 6 0 Leucine Rich Repeat DUF1908 PF08926.11 EGC39367.1 - 0.21 10.6 0.0 0.3 10.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) FNIP PF05725.12 EGC39368.1 - 6.2e-40 135.1 2.2 2.6e-15 56.3 0.1 3.0 2 1 0 3 3 3 3 FNIP Repeat Phage_min_tail PF05939.13 EGC39368.1 - 0.018 15.4 0.0 2.3 8.6 0.0 2.9 1 1 2 3 3 3 0 Phage minor tail protein FNIP PF05725.12 EGC39369.1 - 1.9e-138 450.4 52.7 7.3e-16 58.1 0.7 11.9 5 3 3 12 12 12 12 FNIP Repeat SPATA6 PF14909.6 EGC39369.1 - 5.3e-06 26.6 0.0 7.5 6.7 0.0 6.1 1 1 4 8 8 8 3 Spermatogenesis-assoc protein 6 MCM_OB PF17207.3 EGC39369.1 - 0.00037 20.4 0.0 13 5.6 0.0 6.2 4 2 6 11 11 11 1 MCM OB domain LRR_8 PF13855.6 EGC39369.1 - 0.00065 19.4 10.1 3.1 7.6 0.5 6.2 2 2 5 8 8 8 3 Leucine rich repeat HTH_ABP1_N PF18107.1 EGC39369.1 - 0.077 12.7 3.3 3e+02 1.2 0.0 7.1 12 0 0 12 12 12 0 Fission yeast centromere protein N-terminal domain LRR_1 PF00560.33 EGC39369.1 - 2.6 8.9 14.5 27 5.8 0.0 8.3 6 2 2 8 8 8 0 Leucine Rich Repeat Ras PF00071.22 EGC39370.1 - 4.6e-59 198.6 0.0 5.5e-59 198.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39370.1 - 9.3e-35 119.5 0.0 1.3e-34 119.0 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39370.1 - 9.5e-18 64.3 0.0 1.2e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC39370.1 - 1.3e-07 31.7 0.0 1.8e-07 31.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC39370.1 - 2.6e-05 23.9 0.0 0.0002 20.9 0.0 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGC39370.1 - 9.3e-05 22.3 0.0 0.002 18.0 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein Gtr1_RagA PF04670.12 EGC39370.1 - 0.00014 21.4 0.0 0.00017 21.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RsgA_GTPase PF03193.16 EGC39370.1 - 0.0029 17.5 0.0 0.24 11.3 0.0 2.3 2 1 0 2 2 2 1 RsgA GTPase SRPRB PF09439.10 EGC39370.1 - 0.0034 16.8 0.0 0.0057 16.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGC39370.1 - 0.028 14.2 0.0 0.4 10.4 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.18 EGC39370.1 - 0.051 13.1 0.0 0.67 9.5 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_16 PF13191.6 EGC39370.1 - 0.1 13.0 0.1 0.17 12.3 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain zf-C3HC4_3 PF13920.6 EGC39371.1 - 3.4e-09 36.4 5.8 5.2e-09 35.8 5.8 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39371.1 - 8.8e-09 35.6 9.1 1.4e-08 35.0 9.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC39371.1 - 1.4e-08 34.4 9.3 2.6e-08 33.6 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39371.1 - 3.2e-08 33.3 8.4 5.3e-08 32.6 8.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39371.1 - 2.7e-07 30.8 8.9 7.4e-07 29.4 8.9 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC39371.1 - 7e-06 25.8 9.5 5.6e-05 22.9 10.0 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC39371.1 - 2.8e-05 24.0 5.3 5.5e-05 23.1 5.3 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGC39371.1 - 0.00012 22.1 1.8 0.00023 21.2 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC39371.1 - 0.0015 18.5 9.4 0.011 15.7 9.8 2.1 1 1 1 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC39371.1 - 0.0022 18.1 9.3 0.0047 17.1 9.3 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC39371.1 - 0.012 15.3 9.8 0.082 12.7 10.1 2.0 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC39371.1 - 0.032 14.4 2.1 0.065 13.4 2.1 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 TerY_C PF15616.6 EGC39371.1 - 0.065 13.4 6.8 0.12 12.5 6.8 1.7 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_6 PF14835.6 EGC39371.1 - 0.089 12.7 3.3 0.16 11.8 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein HypA PF01155.19 EGC39371.1 - 0.57 10.2 3.4 0.44 10.6 1.4 1.7 1 1 1 2 2 2 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF620 PF04788.12 EGC39372.1 - 0.1 12.0 0.1 0.18 11.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF620) Sigma70_ner PF04546.13 EGC39372.1 - 0.1 12.4 12.1 1.9 8.3 0.8 4.0 4 0 0 4 4 4 0 Sigma-70, non-essential region Telomere_reg-2 PF10193.9 EGC39372.1 - 0.11 13.0 5.3 3.7 8.0 0.7 4.0 3 0 0 3 3 3 0 Telomere length regulation protein FAM176 PF14851.6 EGC39372.1 - 0.4 10.3 6.6 8 6.1 1.7 2.5 2 0 0 2 2 2 0 FAM176 family DUF4611 PF15387.6 EGC39372.1 - 0.41 10.9 11.7 3.6 7.9 1.5 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) EST1 PF10374.9 EGC39372.1 - 1.2 9.7 0.0 1.2 9.7 0.0 5.0 4 2 0 4 4 4 0 Telomerase activating protein Est1 Sporozoite_P67 PF05642.11 EGC39372.1 - 2 6.4 6.4 1.4 6.9 0.1 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen CENP-B_dimeris PF09026.10 EGC39372.1 - 9.5 6.7 24.0 0.45 10.9 4.1 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain TrkH PF02386.16 EGC39374.1 - 8.1e-59 199.4 25.8 1.1e-54 185.8 20.8 3.2 2 1 0 2 2 2 2 Cation transport protein LAP1C PF05609.12 EGC39374.1 - 0.025 13.7 6.0 0.037 13.1 6.0 1.2 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Macoilin PF09726.9 EGC39374.1 - 0.4 9.2 15.6 0.54 8.7 15.6 1.1 1 0 0 1 1 1 0 Macoilin family DUF2457 PF10446.9 EGC39374.1 - 1.2 8.2 22.7 1.7 7.7 22.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ras PF00071.22 EGC39375.1 - 1.1e-49 168.2 0.0 1.3e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39375.1 - 2.3e-31 108.5 0.0 3.5e-31 107.9 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39375.1 - 7.3e-16 58.1 0.0 9.6e-16 57.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39375.1 - 3.8e-07 29.7 0.0 4.9e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC39375.1 - 0.0005 20.1 0.0 0.00073 19.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC39375.1 - 0.00069 19.2 0.0 0.027 14.0 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.10 EGC39375.1 - 0.0015 18.0 0.0 0.002 17.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.9 EGC39375.1 - 0.0017 18.1 0.1 0.086 12.6 0.1 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation G-alpha PF00503.20 EGC39375.1 - 0.0035 16.6 0.0 0.0042 16.3 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit DUF3430 PF11912.8 EGC39376.1 - 1e-32 113.9 28.3 1e-32 113.9 28.3 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) LPMO_10 PF03067.15 EGC39377.1 - 2.2e-05 25.2 0.1 3.6e-05 24.5 0.1 1.4 1 1 0 1 1 1 1 Lytic polysaccharide mono-oxygenase, cellulose-degrading zf-HIT PF04438.16 EGC39378.1 - 3.6e-07 29.9 10.2 5.3e-07 29.4 10.2 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.18 EGC39378.1 - 5e-05 23.3 9.5 7.9e-05 22.7 9.5 1.3 1 0 0 1 1 1 1 MYND finger Spore_coat_CotO PF14153.6 EGC39378.1 - 0.02 14.8 12.9 0.029 14.3 12.9 1.2 1 0 0 1 1 1 0 Spore coat protein CotO zf-Mss51 PF13824.6 EGC39378.1 - 0.073 13.2 5.4 0.23 11.6 5.4 1.9 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 CEBP_ZZ PF16366.5 EGC39378.1 - 0.074 13.3 5.1 0.14 12.4 5.1 1.4 1 0 0 1 1 1 0 Cytoplasmic polyadenylation element-binding protein ZZ domain ORC6 PF05460.13 EGC39378.1 - 0.079 12.2 13.0 0.1 11.9 13.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Neur_chan_memb PF02932.16 EGC39378.1 - 0.37 10.8 6.2 0.45 10.5 6.2 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.18 EGC39378.1 - 1.3 7.4 3.0 1.2 7.4 3.0 1.1 1 0 0 1 1 1 0 Membrane transport protein GEMIN8 PF15348.6 EGC39378.1 - 1.9 8.8 10.9 3.2 8.0 10.9 1.3 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 SDA1 PF05285.12 EGC39378.1 - 2.8 7.3 16.2 4 6.8 16.2 1.2 1 0 0 1 1 1 0 SDA1 DUF4551 PF15087.6 EGC39378.1 - 3.5 6.3 13.5 4.3 6.0 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Ndc1_Nup PF09531.10 EGC39378.1 - 4.2 6.0 7.1 4.8 5.8 7.1 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Paramyxo_ncap PF00973.19 EGC39378.1 - 8.2 5.2 8.6 9.9 4.9 8.6 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein HutD PF05962.11 EGC39379.1 - 7.8e-27 94.4 0.0 5.1e-24 85.3 0.0 2.4 2 1 0 2 2 2 2 HutD DUF2181 PF10223.9 EGC39379.1 - 0.064 12.7 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2181) RRM_1 PF00076.22 EGC39380.1 - 5.4e-22 77.4 0.1 6.4e-22 77.2 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_7 PF16367.5 EGC39380.1 - 0.0007 19.7 0.1 0.0018 18.4 0.1 1.6 1 1 0 1 1 1 1 RNA recognition motif RL PF17797.1 EGC39380.1 - 0.0025 17.7 0.1 0.0033 17.3 0.1 1.2 1 0 0 1 1 1 1 RL domain Calcipressin PF04847.12 EGC39380.1 - 0.0065 16.2 0.0 0.0073 16.1 0.0 1.1 1 0 0 1 1 1 1 Calcipressin Nup35_RRM_2 PF14605.6 EGC39380.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.2 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PHM7_cyt PF14703.6 EGC39380.1 - 0.015 15.5 0.3 0.025 14.8 0.4 1.2 1 1 0 1 1 1 0 Cytosolic domain of 10TM putative phosphate transporter LAG1-DNAbind PF09271.11 EGC39380.1 - 0.052 14.2 0.0 0.064 13.9 0.0 1.1 1 0 0 1 1 1 0 LAG1, DNA binding Limkain-b1 PF11608.8 EGC39380.1 - 0.068 13.2 0.1 0.1 12.7 0.1 1.4 1 1 0 1 1 1 0 Limkain b1 RRM_5 PF13893.6 EGC39380.1 - 0.075 12.6 0.0 0.085 12.5 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) TCTP PF00838.17 EGC39381.1 - 3.1e-59 200.0 4.8 3.5e-59 199.9 4.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein tRNA_int_endo PF01974.17 EGC39382.1 - 7.6e-20 70.8 0.2 1.9e-19 69.5 0.1 1.7 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.14 EGC39382.1 - 9.7e-06 25.2 1.1 0.00046 19.8 0.1 2.7 2 1 0 2 2 2 1 tRNA intron endonuclease, N-terminal domain Secretin_N_2 PF07655.13 EGC39382.1 - 0.0011 19.5 8.2 0.0011 19.5 8.2 2.6 2 0 0 2 2 2 1 Secretin N-terminal domain ALMT PF11744.8 EGC39382.1 - 6 5.6 9.1 6.5 5.5 1.4 2.1 2 0 0 2 2 2 0 Aluminium activated malate transporter DUF4834 PF16118.5 EGC39382.1 - 6 7.9 12.0 3.8 8.5 1.4 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) E1-E2_ATPase PF00122.20 EGC39383.1 - 1.9e-49 167.7 2.0 9.1e-49 165.4 0.2 2.8 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.26 EGC39383.1 - 1.2e-20 74.7 0.0 3.2e-20 73.3 0.0 1.7 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.26 EGC39383.1 - 3.2e-12 46.0 0.0 7.4e-12 44.8 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Cation_ATPase PF13246.6 EGC39383.1 - 0.00047 20.2 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Cation transport ATPase (P-type) Hydrolase_3 PF08282.12 EGC39383.1 - 0.00047 20.0 0.2 0.0017 18.1 0.1 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Thioredoxin PF00085.20 EGC39384.1 - 6.1e-10 39.0 0.1 6.6e-10 38.9 0.1 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.20 EGC39385.1 - 2.1e-05 24.5 0.1 2.1e-05 24.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin ILEI PF15711.5 EGC39386.1 - 6.7e-18 65.0 0.5 2.1e-17 63.4 0.5 1.9 1 0 0 1 1 1 1 Interleukin-like EMT inducer Snf7 PF03357.21 EGC39387.1 - 4.8e-39 133.7 32.5 5.9e-39 133.4 32.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.14 EGC39387.1 - 0.0033 17.4 11.5 0.0045 16.9 11.5 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway NLRC4_HD PF17889.1 EGC39387.1 - 0.21 11.9 4.7 1.8 8.9 0.8 2.4 1 1 1 2 2 2 0 NLRC4 helical domain Sec23_trunk PF04811.15 EGC39389.1 - 8.6e-16 58.2 0.0 6.4e-15 55.4 0.0 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.15 EGC39389.1 - 1e-08 35.1 4.3 2.8e-08 33.7 4.3 1.8 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.12 EGC39389.1 - 1.6e-08 35.2 0.1 5.1e-08 33.6 0.1 2.0 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGC39389.1 - 0.00067 19.4 2.2 0.0011 18.7 0.2 2.5 4 0 0 4 4 4 1 Sec23/Sec24 helical domain Gelsolin PF00626.22 EGC39389.1 - 0.0026 17.6 0.4 0.01 15.7 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat Pox_Ag35 PF03286.14 EGC39389.1 - 0.36 10.6 6.3 1.3 8.7 6.3 1.9 2 0 0 2 2 2 0 Pox virus Ag35 surface protein PHD PF00628.29 EGC39389.1 - 0.73 9.8 4.5 1.6 8.7 4.5 1.5 1 0 0 1 1 1 0 PHD-finger Vps36-NZF-N PF16988.5 EGC39389.1 - 0.78 9.2 10.5 0.072 12.5 4.2 2.7 2 0 0 2 2 2 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain FYVE_2 PF02318.16 EGC39389.1 - 0.85 9.9 7.2 0.17 12.1 2.8 2.1 2 0 0 2 2 2 0 FYVE-type zinc finger BTB_2 PF02214.22 EGC39389.1 - 1.2 9.5 6.5 1.2 9.5 0.3 3.4 3 0 0 3 3 3 0 BTB/POZ domain FNIP PF05725.12 EGC39391.1 - 4e-08 33.3 2.8 5.4e-07 29.7 0.4 8.6 6 2 2 10 10 10 3 FNIP Repeat Kdo_hydroxy PF11004.8 EGC39391.1 - 0.052 12.8 0.2 0.21 10.8 0.2 2.1 1 1 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase Ank_2 PF12796.7 EGC39391.1 - 0.13 12.9 0.0 0.59 10.8 0.0 2.2 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) DUF4922 PF16269.5 EGC39393.1 - 6.2e-06 26.1 0.0 1.1e-05 25.4 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4922) GalP_UDP_tr_C PF02744.17 EGC39393.1 - 0.00029 20.6 0.0 0.0012 18.6 0.0 2.0 1 1 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.22 EGC39393.1 - 0.01 16.3 0.1 0.024 15.1 0.1 1.7 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain DUF4922 PF16269.5 EGC39394.1 - 0.043 13.6 0.1 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4922) CwfJ_C_1 PF04677.15 EGC39394.1 - 0.051 13.4 0.8 0.14 12.0 0.8 1.8 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 PEMT PF04191.13 EGC39396.1 - 5.7e-27 94.2 5.3 5.7e-27 94.2 5.3 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.16 EGC39396.1 - 0.056 13.4 0.3 0.056 13.4 0.3 2.4 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase TNFR_16_TM PF18422.1 EGC39396.1 - 8.4 6.4 8.2 0.68 9.9 1.7 2.3 2 0 0 2 2 2 0 Tumor necrosis factor receptor member 16 trans-membrane domain DUF1643 PF07799.12 EGC39397.1 - 0.36 11.0 2.6 0.43 10.8 1.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1643) O_anti_polymase PF01901.16 EGC39397.1 - 1.2 8.3 4.3 1.4 8.1 4.1 1.3 1 1 0 1 1 1 0 Putative O-antigen polymerase DUF4083 PF13314.6 EGC39397.1 - 2.6 8.1 9.6 2.4 8.2 6.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) FNIP PF05725.12 EGC39398.1 - 7.9e-32 109.2 5.2 3.6e-12 46.3 0.1 2.6 1 1 2 3 3 3 3 FNIP Repeat DUF1769 PF08588.10 EGC39398.1 - 0.019 15.1 0.3 8.8 6.6 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1769) OTU PF02338.19 EGC39400.1 - 3.3e-12 47.0 3.2 5.7e-12 46.2 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease Ndc1_Nup PF09531.10 EGC39400.1 - 0.0025 16.6 15.3 0.0031 16.3 15.3 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup DUF4551 PF15087.6 EGC39400.1 - 1.3 7.8 21.5 1.6 7.4 21.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) FixO PF02433.15 EGC39400.1 - 9 5.7 15.8 6.5 6.1 12.8 2.1 2 1 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO zf-TRAF PF02176.18 EGC39401.1 - 2.6e-13 50.4 31.1 3.1e-11 43.8 8.1 3.8 2 1 2 4 4 4 3 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC39401.1 - 4.3e-06 27.1 28.2 0.00016 22.1 6.4 3.5 2 2 1 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_2 PF13923.6 EGC39401.1 - 0.0047 16.7 2.1 0.0047 16.7 2.1 4.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39401.1 - 0.017 15.4 2.4 0.017 15.4 2.4 3.9 3 0 0 3 3 3 0 Ring finger domain Sina PF03145.16 EGC39401.1 - 0.018 15.0 25.1 0.068 13.1 2.5 3.7 1 1 3 4 4 4 0 Seven in absentia protein family zf-LYAR PF08790.11 EGC39401.1 - 0.098 12.6 6.0 1.3 9.0 0.1 3.3 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger zf-C2HC_2 PF13913.6 EGC39401.1 - 0.13 12.2 0.1 0.13 12.2 0.1 4.1 5 0 0 5 5 5 0 zinc-finger of a C2HC-type zf-C2H2_9 PF16293.5 EGC39401.1 - 0.26 11.2 0.0 0.26 11.2 0.0 3.9 6 0 0 6 6 6 0 C2H2 type zinc-finger (1 copy) CBF PF03914.17 EGC39402.1 - 0.072 13.1 0.4 5.9 6.9 0.3 2.5 2 0 0 2 2 2 0 CBF/Mak21 family DFRP_C PF16543.5 EGC39403.1 - 1e-20 74.0 4.4 1e-20 74.0 4.4 5.5 4 3 3 7 7 7 1 DRG Family Regulatory Proteins, Tma46 Torus PF16131.5 EGC39403.1 - 0.00084 20.0 19.7 0.015 16.0 6.1 4.2 2 1 1 3 3 3 2 Torus domain zf-CCCH PF00642.24 EGC39403.1 - 0.0011 18.8 1.6 0.0011 18.8 1.6 2.9 3 0 0 3 3 3 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf_CCCH_4 PF18345.1 EGC39403.1 - 0.0013 18.7 7.2 0.0013 18.7 7.2 3.1 3 0 0 3 3 3 1 Zinc finger domain zf-CCCH_4 PF18044.1 EGC39403.1 - 0.0015 18.3 2.5 0.0015 18.3 2.5 2.9 3 0 0 3 3 3 1 CCCH-type zinc finger DUF3810 PF12725.7 EGC39403.1 - 0.042 13.2 1.2 0.084 12.2 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) RNase_H2_suC PF08615.11 EGC39403.1 - 2.8 8.1 17.5 31 4.7 3.0 3.5 2 1 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) zf-CCCH_2 PF14608.6 EGC39403.1 - 6.5 7.4 16.6 3.6 8.2 6.6 2.9 2 1 0 2 2 2 0 RNA-binding, Nab2-type zinc finger Pkinase PF00069.25 EGC39404.1 - 2.8e-68 230.1 0.0 6.8e-68 228.9 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39404.1 - 3.6e-54 183.8 0.0 2.1e-53 181.3 0.0 2.1 1 1 1 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC39404.1 - 5.9e-08 31.9 0.1 5.9e-08 31.9 0.1 2.4 2 1 0 2 2 2 1 Fungal protein kinase PBD PF00786.28 EGC39404.1 - 0.00012 22.4 0.1 0.00061 20.1 0.1 2.3 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.6 EGC39404.1 - 0.00038 19.9 0.1 0.00099 18.5 0.1 1.6 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.9 EGC39404.1 - 0.0035 16.9 0.5 0.019 14.5 0.0 2.2 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL ABC1 PF03109.16 EGC39404.1 - 0.0071 16.5 0.2 0.028 14.6 0.0 2.0 2 0 0 2 2 2 1 ABC1 family APH PF01636.23 EGC39404.1 - 0.0078 16.2 0.0 0.42 10.5 0.1 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family CdiI_2 PF18593.1 EGC39404.1 - 0.14 12.8 0.0 0.48 11.1 0.0 1.8 1 0 0 1 1 1 0 CdiI immunity protein DUF3533 PF12051.8 EGC39404.1 - 2.1 7.2 8.1 3.8 6.3 2.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3533) DnaJ PF00226.31 EGC39406.1 - 5.5e-24 84.1 1.6 5.5e-24 84.1 1.6 2.3 2 0 0 2 2 2 1 DnaJ domain V_ATPase_I PF01496.19 EGC39406.1 - 0.0025 15.8 6.6 0.0039 15.2 6.6 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF3792 PF12670.7 EGC39406.1 - 1.6 8.9 9.1 6.2 7.0 3.3 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3792) HUN PF08729.10 EGC39407.1 - 2.6e-09 36.9 13.8 1.7e-08 34.3 13.8 2.5 1 0 0 1 1 1 1 HPC2 and ubinuclein domain Pyridoxal_deC PF00282.19 EGC39408.1 - 3.5e-18 65.5 0.0 5.6e-18 64.8 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGC39408.1 - 2.9e-17 62.7 0.1 3.2e-16 59.2 0.1 2.3 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGC39408.1 - 0.00012 21.3 0.0 0.00057 19.2 0.1 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGC39408.1 - 0.0045 16.3 0.2 0.0068 15.7 0.2 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGC39408.1 - 0.02 13.4 0.0 0.037 12.5 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tna_leader PF08053.11 EGC39408.1 - 0.023 14.6 0.0 0.073 13.0 0.0 1.9 1 0 0 1 1 1 0 Tryptophanase operon leader peptide Peptidase_M20 PF01546.28 EGC39410.1 - 1.6e-34 119.5 0.0 2.1e-34 119.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC39410.1 - 2.9e-16 59.3 0.0 5.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain CH PF00307.31 EGC39411.1 - 9.2e-16 58.0 0.1 9.2e-16 58.0 0.1 3.1 3 1 0 3 3 3 1 Calponin homology (CH) domain CemA PF03040.14 EGC39411.1 - 1.4 8.8 17.4 4.7 7.1 17.4 2.0 1 0 0 1 1 1 0 CemA family CH PF00307.31 EGC39412.1 - 1.3e-17 64.0 0.0 1.6e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain RNA_GG_bind PF10258.9 EGC39413.1 - 1.3e-08 34.8 0.4 1.8e-07 31.1 0.4 2.7 1 1 0 1 1 1 1 PHAX RNA-binding domain BLM10_mid PF16507.5 EGC39414.1 - 1.3e-46 159.4 16.7 4.8e-39 134.4 6.6 3.9 2 1 1 3 3 3 2 Proteasome-substrate-size regulator, mid region DUF3437 PF11919.8 EGC39414.1 - 5e-29 100.1 0.6 1.3e-25 89.1 0.1 4.5 4 0 0 4 4 4 2 Domain of unknown function (DUF3437) DUF2207 PF09972.9 EGC39415.1 - 0.022 13.6 6.0 0.024 13.4 6.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) TRP PF06011.12 EGC39415.1 - 0.056 12.2 8.0 0.073 11.8 8.0 1.2 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel SdpI PF13630.6 EGC39415.1 - 2.2 8.5 7.3 8.9 6.5 4.8 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family Stevor PF17410.2 EGC39415.1 - 4.5 6.7 8.1 5.1 6.6 8.1 1.2 1 1 0 1 1 1 0 Subtelomeric Variable Open Reading frame T2SSF PF00482.23 EGC39415.1 - 7.1 6.6 7.4 53 3.8 0.0 2.1 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein F DcuA_DcuB PF03605.14 EGC39416.1 - 0.011 14.7 0.4 0.043 12.7 0.5 1.7 1 1 1 2 2 2 0 Anaerobic c4-dicarboxylate membrane transporter Cytochrom_B_C PF00032.17 EGC39416.1 - 0.023 15.0 1.3 0.032 14.5 1.3 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Pox_A14 PF05767.12 EGC39416.1 - 0.059 13.5 3.6 0.091 12.9 3.6 1.4 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 Sec20 PF03908.13 EGC39416.1 - 0.17 11.8 1.6 3.8 7.5 0.4 2.2 2 0 0 2 2 2 0 Sec20 Pox_LP_H2 PF03356.15 EGC39416.1 - 0.22 11.4 2.9 0.2 11.5 1.7 1.5 1 1 1 2 2 2 0 Viral late protein H2 ABC2_membrane_3 PF12698.7 EGC39416.1 - 0.31 10.1 8.8 0.15 11.1 6.5 1.5 1 1 1 2 2 2 0 ABC-2 family transporter protein Tmemb_9 PF05434.11 EGC39416.1 - 0.45 10.4 5.2 0.22 11.4 3.0 1.5 2 0 0 2 2 2 0 TMEM9 PMP22_Claudin PF00822.20 EGC39416.1 - 0.45 10.4 3.9 7.1 6.5 1.2 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Orf78 PF06024.12 EGC39416.1 - 0.62 10.4 6.4 2.1 8.7 6.2 2.0 1 1 0 1 1 1 0 Orf78 (ac78) CD225 PF04505.12 EGC39416.1 - 3.7 7.8 5.8 0.27 11.4 0.8 1.7 2 0 0 2 2 2 0 Interferon-induced transmembrane protein GHMP_kinases_N PF00288.26 EGC39418.1 - 8.9e-15 54.7 0.7 8.9e-15 54.7 0.7 1.8 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.13 EGC39418.1 - 3.8e-07 30.4 0.0 2.9e-06 27.5 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal VCH_CASS14 PF18315.1 EGC39418.1 - 0.08 13.0 0.1 0.18 11.9 0.1 1.5 1 0 0 1 1 1 0 Integron cassette protein VCH_CASS1 chain CAF1C_H4-bd PF12265.8 EGC39419.1 - 2.7e-27 94.8 1.5 2.3e-26 91.8 0.7 2.7 3 0 0 3 3 3 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex WD40 PF00400.32 EGC39419.1 - 4.6e-26 90.5 15.2 6.5e-07 29.9 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat FDX-ACB PF03147.14 EGC39420.1 - 0.059 13.8 0.0 0.12 12.8 0.0 1.5 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain FNIP PF05725.12 EGC39421.1 - 7.8e-12 45.2 29.2 4e-06 26.9 0.1 7.5 4 1 1 6 6 6 5 FNIP Repeat DUF3683 PF12447.8 EGC39421.1 - 0.68 10.1 8.3 0.042 14.0 0.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3683) Peptidase_C97 PF05903.14 EGC39422.1 - 3.4e-28 98.4 0.3 3.9e-28 98.2 0.3 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Cys_Met_Meta_PP PF01053.20 EGC39424.1 - 1.5e-155 517.5 0.0 1.7e-155 517.3 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.21 EGC39424.1 - 1.4e-07 31.1 0.0 2e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.19 EGC39424.1 - 2.2e-05 23.6 0.0 3.3e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V DegT_DnrJ_EryC1 PF01041.17 EGC39424.1 - 8.7e-05 22.0 0.1 0.00039 19.8 0.1 2.0 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.11 EGC39424.1 - 0.00028 19.6 0.0 0.00047 18.8 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Mod_r PF07200.13 EGC39425.1 - 6.7e-25 87.9 18.9 6.7e-25 87.9 18.9 2.1 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Mitovir_RNA_pol PF05919.11 EGC39425.1 - 2 7.5 8.8 1.2 8.2 6.8 1.5 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase PHO4 PF01384.20 EGC39426.1 - 0.074 12.1 0.0 0.074 12.1 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family Myc_target_1 PF15179.6 EGC39426.1 - 0.18 11.7 0.0 0.18 11.7 0.0 1.0 1 0 0 1 1 1 0 Myc target protein 1 Sec1 PF00995.23 EGC39427.1 - 8.5e-95 319.1 29.4 9.7e-95 318.9 29.4 1.0 1 0 0 1 1 1 1 Sec1 family PIG-U PF06728.13 EGC39428.1 - 4.2e-114 381.6 44.5 5.5e-114 381.2 44.5 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U DUF4690 PF15756.5 EGC39429.1 - 0.0011 19.5 0.1 0.0029 18.2 0.1 1.7 1 0 0 1 1 1 1 Small Novel Rich in Cartilage Podoplanin PF05808.11 EGC39429.1 - 0.21 11.7 1.0 0.54 10.3 1.0 1.6 1 0 0 1 1 1 0 Podoplanin FNIP PF05725.12 EGC39430.1 - 0.00025 21.1 0.3 0.00025 21.1 0.3 7.4 7 0 0 7 7 7 2 FNIP Repeat Kdo_hydroxy PF11004.8 EGC39430.1 - 0.025 13.8 0.1 0.066 12.5 0.1 1.7 1 0 0 1 1 1 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase USP7_ICP0_bdg PF12436.8 EGC39431.1 - 1.6e-56 191.3 0.1 3.3e-56 190.3 0.1 1.6 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 UCH PF00443.29 EGC39431.1 - 2.2e-50 171.6 0.7 2.2e-50 171.6 0.7 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_C2 PF14533.6 EGC39431.1 - 1.9e-43 148.6 13.3 4.4e-42 144.1 5.7 4.3 3 1 0 3 3 3 1 Ubiquitin-specific protease C-terminal UCH_1 PF13423.6 EGC39431.1 - 3.4e-21 76.2 0.0 3.4e-21 76.2 0.0 3.5 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Ubiquitin_2 PF14560.6 EGC39431.1 - 0.00028 21.3 0.5 0.032 14.7 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin-like domain ubiquitin PF00240.23 EGC39431.1 - 0.008 15.9 1.9 3.6 7.4 0.1 3.4 3 0 0 3 3 3 2 Ubiquitin family TFIIA PF03153.13 EGC39431.1 - 0.34 10.8 24.1 0.13 12.3 4.6 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Peptidase_C98 PF15499.6 EGC39431.1 - 3 7.3 8.1 3.4 7.1 0.1 3.3 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase FAM178 PF14816.6 EGC39431.1 - 6 5.7 12.8 0.015 14.3 2.3 1.8 2 0 0 2 2 2 0 Family of unknown function, FAM178 DDHD PF02862.17 EGC39431.1 - 6.4 6.9 13.3 4 7.5 2.3 2.5 2 0 0 2 2 2 0 DDHD domain Ribosomal_L30_N PF08079.12 EGC39432.1 - 1.9e-24 85.7 2.9 3e-24 85.1 2.9 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.20 EGC39432.1 - 6.9e-21 73.9 1.6 3.8e-20 71.5 1.8 2.2 2 0 0 2 2 2 1 Ribosomal protein L30p/L7e DnaJ PF00226.31 EGC39433.1 - 0.0048 17.0 0.3 0.02 15.0 0.0 2.2 2 0 0 2 2 2 1 DnaJ domain Cnl2_NKP2 PF09447.10 EGC39433.1 - 0.0086 16.2 0.2 0.13 12.4 0.0 2.9 2 0 0 2 2 2 1 Cnl2/NKP2 family protein zf-TRAF PF02176.18 EGC39434.1 - 2.3e-13 50.6 17.5 9.1e-11 42.3 6.8 4.3 2 1 2 4 4 4 2 TRAF-type zinc finger Sina PF03145.16 EGC39434.1 - 3e-06 27.3 27.3 5.5e-05 23.2 1.7 4.3 2 1 3 5 5 5 3 Seven in absentia protein family zf-C3HC4_3 PF13920.6 EGC39434.1 - 0.00013 21.7 6.7 0.00013 21.7 6.7 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.12 EGC39434.1 - 0.0026 18.3 1.9 0.0064 17.1 1.9 1.7 1 0 0 1 1 1 1 SlyX zf-TRAF_2 PF15965.5 EGC39434.1 - 0.0039 17.6 26.4 0.015 15.7 2.5 3.5 1 1 3 4 4 4 3 TRAF-like zinc-finger DUF16 PF01519.16 EGC39434.1 - 0.007 16.8 4.1 0.007 16.8 4.1 2.2 2 0 0 2 2 2 1 Protein of unknown function DUF16 TRAF6_Z2 PF18048.1 EGC39434.1 - 0.15 12.2 7.2 0.057 13.5 3.2 2.4 2 0 0 2 2 2 0 TNF receptor-associated factor 6 zinc finger 2 UPF0449 PF15136.6 EGC39434.1 - 0.18 12.3 1.4 0.46 11.0 1.4 1.7 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 zf-C3HC4_2 PF13923.6 EGC39434.1 - 0.27 11.1 15.1 0.057 13.3 8.9 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) HSP70 PF00012.20 EGC39435.1 - 9.6e-253 839.8 15.3 1.1e-252 839.6 15.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGC39435.1 - 8.4e-19 67.6 1.0 2.7e-17 62.6 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein FtsA PF14450.6 EGC39435.1 - 6.5e-05 23.3 6.0 0.3 11.5 0.1 3.9 3 2 0 3 3 3 3 Cell division protein FtsA Hydantoinase_A PF01968.18 EGC39435.1 - 0.0011 18.3 0.8 0.63 9.3 0.1 2.7 2 0 0 2 2 2 2 Hydantoinase/oxoprolinase DDR PF08841.10 EGC39435.1 - 0.008 15.2 0.2 0.2 10.6 0.1 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.16 EGC39435.1 - 0.016 15.0 0.0 0.037 13.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDE_Tnp_IS1 PF03400.13 EGC39435.1 - 0.14 12.5 0.0 1.5 9.1 0.0 2.3 2 0 0 2 2 2 0 IS1 transposase Radial_spoke_3 PF06098.11 EGC39435.1 - 0.31 10.3 9.8 0.032 13.5 4.8 1.7 2 0 0 2 2 2 0 Radial spoke protein 3 Pex19 PF04614.12 EGC39435.1 - 1.2 8.8 10.7 0.13 12.0 3.6 2.2 2 0 0 2 2 2 0 Pex19 protein family DUF4795 PF16043.5 EGC39435.1 - 3.7 7.1 14.9 0.46 10.1 4.4 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF4795) Fes1 PF08609.10 EGC39435.1 - 6.6 7.7 8.0 1.2 10.0 1.4 3.0 3 0 0 3 3 3 0 Nucleotide exchange factor Fes1 DUF5422 PF17459.2 EGC39436.1 - 0.3 11.3 3.3 0.49 10.6 3.3 1.4 1 1 0 1 1 1 0 Family of unknown function (DUF5422) Glyco_hydro_25 PF01183.20 EGC39437.1 - 1.2e-07 32.1 2.1 1.4e-07 31.8 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 zf-C4pol PF14260.6 EGC39437.1 - 0.018 15.5 0.3 0.045 14.2 0.3 1.7 1 0 0 1 1 1 0 C4-type zinc-finger of DNA polymerase delta Syntaxin_2 PF14523.6 EGC39438.1 - 2.1e-05 24.8 6.7 2.1e-05 24.8 6.7 2.8 1 1 1 2 2 2 1 Syntaxin-like protein Syntaxin PF00804.25 EGC39438.1 - 0.0003 20.5 8.0 0.0021 17.8 8.0 2.1 1 1 0 1 1 1 1 Syntaxin SNARE PF05739.19 EGC39438.1 - 0.0038 17.2 0.2 0.01 15.8 0.2 1.7 1 0 0 1 1 1 1 SNARE domain DUF948 PF06103.11 EGC39438.1 - 0.083 13.2 3.0 8.7 6.7 0.8 2.9 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) GLTSCR1 PF15249.6 EGC39438.1 - 0.092 13.2 1.6 0.89 10.0 0.0 2.5 1 1 0 2 2 2 0 Conserved region of unknown function on GLTSCR protein MCPsignal PF00015.21 EGC39438.1 - 0.11 12.4 0.5 0.24 11.2 0.4 1.7 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Osmo_CC PF08946.10 EGC39438.1 - 4.2 7.7 0.0 4.2 7.7 0.0 3.8 5 0 0 5 5 5 0 Osmosensory transporter coiled coil Asn_synthase PF00733.21 EGC39439.1 - 9.7e-72 242.6 0.0 1.2e-71 242.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.6 EGC39439.1 - 5.1e-41 139.4 0.0 1e-40 138.4 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC39439.1 - 1.5e-35 122.3 0.0 2.1e-35 121.8 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.8 EGC39439.1 - 3.8e-05 23.2 0.0 7.6e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein Utp21 PF04192.12 EGC39440.1 - 1.4e-66 224.4 3.2 4.6e-66 222.7 3.2 1.8 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.32 EGC39440.1 - 3.8e-14 52.8 5.4 1.5 9.8 0.0 8.6 9 0 0 9 9 9 5 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC39440.1 - 2.4e-10 40.6 0.2 0.014 15.7 0.0 5.1 3 2 2 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain ELYS-bb PF16687.5 EGC39440.1 - 0.011 14.3 0.1 0.12 11.0 0.0 2.4 2 1 1 3 3 3 0 beta-propeller of ELYS nucleoporin Cass2 PF14526.6 EGC39440.1 - 0.081 13.1 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Integron-associated effector binding protein Utp12 PF04003.12 EGC39440.1 - 0.094 13.0 0.0 0.18 12.1 0.0 1.5 1 0 0 1 1 1 0 Dip2/Utp12 Family PALB2_WD40 PF16756.5 EGC39440.1 - 0.14 11.1 0.0 0.56 9.1 0.0 2.0 1 0 0 1 1 1 0 Partner and localizer of BRCA2 WD40 domain Peptidase_C14 PF00656.22 EGC39442.1 - 1.4e-08 35.0 0.1 1.7e-08 34.7 0.1 1.3 1 0 0 1 1 1 1 Caspase domain DivIC PF04977.15 EGC39442.1 - 0.35 10.7 3.8 1.3 8.9 0.6 2.7 2 0 0 2 2 2 0 Septum formation initiator FG-GAP PF01839.23 EGC39443.1 - 1.4e-24 85.9 8.5 9.4e-07 28.9 0.1 4.7 4 0 0 4 4 4 4 FG-GAP repeat Zn_dep_PLPC PF00882.18 EGC39443.1 - 3.7e-20 72.7 0.7 8.8e-20 71.4 0.7 1.6 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.6 EGC39443.1 - 3.4e-11 43.6 17.0 6.1e-06 26.7 2.7 4.8 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.8 EGC39443.1 - 0.0046 16.3 0.1 0.73 9.2 0.0 3.3 3 0 0 3 3 3 1 Insecticide toxin TcdB middle/N-terminal region EF-hand_1 PF00036.32 EGC39443.1 - 0.36 10.5 2.7 5 6.9 0.0 3.3 3 0 0 3 3 3 0 EF hand Tmpp129 PF10272.9 EGC39445.1 - 0.047 13.0 0.5 0.072 12.4 0.5 1.3 1 0 0 1 1 1 0 Putative transmembrane protein precursor DUF2207 PF09972.9 EGC39445.1 - 0.24 10.1 7.1 9.9 4.8 0.1 2.0 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) SieB PF14163.6 EGC39446.1 - 0.08 12.4 1.1 0.15 11.6 0.1 2.0 2 0 0 2 2 2 0 Super-infection exclusion protein B EGF_2 PF07974.13 EGC39446.1 - 0.26 11.7 15.0 0.095 13.1 11.7 2.0 2 0 0 2 2 2 0 EGF-like domain H_lectin PF09458.10 EGC39447.1 - 2.2e-19 69.4 1.1 7.1e-19 67.8 1.1 1.9 1 0 0 1 1 1 1 H-type lectin domain Fascin PF06268.13 EGC39447.1 - 6.2e-07 29.6 0.6 1e-06 29.0 0.6 1.3 1 0 0 1 1 1 1 Fascin domain RicinB_lectin_2 PF14200.6 EGC39447.1 - 6.2e-05 23.6 25.5 0.00031 21.4 0.6 3.3 2 1 0 3 3 3 2 Ricin-type beta-trefoil lectin domain-like LMBR1 PF04791.16 EGC39447.1 - 0.37 9.6 7.8 0.48 9.3 7.8 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Presenilin PF01080.17 EGC39447.1 - 1.6 7.4 13.1 2 7.1 13.1 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.16 EGC39447.1 - 2.6 8.0 6.7 4.2 7.4 6.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.22 EGC39447.1 - 5.5 6.1 5.9 6.7 5.8 5.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter EGF_2 PF07974.13 EGC39448.1 - 8.8 6.8 20.0 0.096 13.1 11.8 2.0 3 0 0 3 3 3 0 EGF-like domain MORN PF02493.20 EGC39449.1 - 2.6e-26 89.9 50.3 0.00014 21.5 0.3 12.3 12 0 0 12 12 12 10 MORN repeat DUF1992 PF09350.10 EGC39449.1 - 0.12 12.6 0.3 3 8.1 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1992) WASH-7_mid PF14744.6 EGC39450.1 - 1.1 8.3 6.0 1 8.4 4.4 1.7 1 1 0 2 2 2 0 WASH complex subunit 7 FixQ PF05545.11 EGC39451.1 - 0.087 12.8 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NSP2-B_epitope PF14757.6 EGC39451.1 - 0.099 12.3 0.4 0.15 11.8 0.4 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Insulin_TMD PF17870.1 EGC39451.1 - 0.13 12.4 1.7 0.25 11.5 1.7 1.5 1 0 0 1 1 1 0 Insulin receptor trans-membrane segment Vpu PF00558.19 EGC39451.1 - 0.13 12.0 0.7 0.23 11.3 0.7 1.4 1 0 0 1 1 1 0 Vpu protein SieB PF14163.6 EGC39452.1 - 0.047 13.2 1.3 0.059 12.9 0.3 1.7 2 0 0 2 2 2 0 Super-infection exclusion protein B NSP2-B_epitope PF14757.6 EGC39452.1 - 0.089 12.5 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein FixQ PF05545.11 EGC39452.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ NSP2-B_epitope PF14757.6 EGC39454.1 - 0.089 12.5 0.3 0.13 11.9 0.3 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein FixQ PF05545.11 EGC39454.1 - 0.15 12.1 0.0 0.29 11.1 0.0 1.5 1 0 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ EGF_2 PF07974.13 EGC39455.1 - 0.058 13.8 11.8 0.17 12.3 11.8 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.13 EGC39456.1 - 0.39 11.1 15.0 0.11 12.9 11.7 1.8 2 0 0 2 2 2 0 EGF-like domain LRR_4 PF12799.7 EGC39457.1 - 5e-11 42.7 41.8 0.026 14.9 3.0 10.9 8 3 3 11 11 11 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGC39457.1 - 1.8e-05 24.4 47.8 0.26 11.4 0.1 12.4 14 0 0 14 14 14 4 Leucine Rich repeat LRR_1 PF00560.33 EGC39457.1 - 0.00011 22.2 32.4 3.9 8.4 0.2 12.2 12 1 0 12 12 12 3 Leucine Rich Repeat LRR_8 PF13855.6 EGC39457.1 - 2.8 7.8 44.7 0.12 12.1 5.9 9.8 8 3 1 9 9 9 0 Leucine rich repeat AA_permease_2 PF13520.6 EGC39458.1 - 1.2e-30 106.7 53.3 1.6e-30 106.3 53.3 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.21 EGC39458.1 - 7.2e-19 67.7 51.6 1.4e-18 66.8 51.6 1.4 1 1 0 1 1 1 1 Amino acid permease NADH_B2 PF14813.6 EGC39459.1 - 0.1 12.4 0.8 0.28 11.0 0.8 1.7 1 0 0 1 1 1 0 NADH dehydrogenase 1 beta subcomplex subunit 2 RNA_pol_Rpb1_5 PF04998.17 EGC39460.1 - 1.3e-89 300.2 2.3 2.6e-89 299.2 2.3 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.12 EGC39460.1 - 5.5e-89 298.6 3.9 5.5e-89 298.6 3.9 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.20 EGC39460.1 - 1e-74 250.3 0.0 4e-74 248.4 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.18 EGC39460.1 - 1.4e-36 125.8 0.1 2e-35 122.0 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.17 EGC39460.1 - 3.9e-30 104.0 0.1 3.9e-30 104.0 0.1 3.1 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 zinc_ribbon_10 PF10058.9 EGC39460.1 - 2.7 7.8 4.9 27 4.6 0.4 2.9 2 0 0 2 2 2 0 Predicted integral membrane zinc-ribbon metal-binding protein Fer4_17 PF13534.6 EGC39460.1 - 3.3 8.3 6.1 5.2 7.7 3.1 2.7 2 0 0 2 2 2 0 4Fe-4S dicluster domain EGF_2 PF07974.13 EGC39461.1 - 0.017 15.5 6.2 0.017 15.5 6.2 2.7 2 0 0 2 2 2 0 EGF-like domain DUF5034 PF16437.5 EGC39461.1 - 0.095 12.7 1.2 0.67 9.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF5034) cEGF PF12662.7 EGC39461.1 - 3.3 7.7 9.9 1 9.4 4.6 2.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Voltage_CLC PF00654.20 EGC39462.1 - 5.9e-94 315.2 26.8 1.3e-93 314.0 22.8 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.28 EGC39462.1 - 7.2e-07 29.6 1.1 0.0011 19.4 0.0 3.3 3 0 0 3 3 3 2 CBS domain XhlA PF10779.9 EGC39462.1 - 0.021 15.0 0.1 0.021 15.0 0.1 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Elong_Iki1 PF10483.9 EGC39463.1 - 1.1e-17 64.5 3.2 1.1e-14 54.7 3.2 3.4 1 1 0 1 1 1 1 Elongator subunit Iki1 Cytomega_UL84 PF06284.11 EGC39463.1 - 0.024 13.1 0.0 0.033 12.7 0.0 1.1 1 0 0 1 1 1 0 Cytomegalovirus UL84 protein FNIP PF05725.12 EGC39464.1 - 0.00019 21.5 16.7 0.018 15.2 3.5 4.7 3 2 1 4 4 4 2 FNIP Repeat HeH PF12949.7 EGC39464.1 - 0.0028 17.3 1.6 0.0064 16.2 1.6 1.6 1 0 0 1 1 1 1 HeH/LEM domain Peptidase_M60_C PF18630.1 EGC39464.1 - 0.046 13.9 0.2 0.24 11.5 0.1 2.2 2 0 0 2 2 2 0 Peptidase M60 C-terminal domain SAP PF02037.27 EGC39464.1 - 7.7 6.4 7.9 6.2 6.7 4.1 3.0 4 1 0 4 4 4 0 SAP domain DUF4337 PF14235.6 EGC39464.1 - 9 6.4 6.7 21 5.2 6.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) PseudoU_synth_2 PF00849.22 EGC39465.1 - 9.5e-16 58.3 0.8 2.5e-15 56.9 0.0 2.1 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.25 EGC39465.1 - 4.6e-12 45.4 2.1 1e-10 41.1 0.2 2.6 2 0 0 2 2 2 1 S4 domain TMEMspv1-c74-12 PF11044.8 EGC39465.1 - 0.76 9.8 5.8 2.9 7.9 5.8 2.0 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein Man-6-P_recep PF02157.15 EGC39466.1 - 0.0054 15.9 1.9 0.0054 15.9 1.9 2.1 2 0 0 2 2 2 2 Mannose-6-phosphate receptor ketoacyl-synt PF00109.26 EGC39468.1 - 1.6e-67 227.8 0.0 2.5e-67 227.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC39468.1 - 9.8e-39 133.7 0.0 1.7e-38 132.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC39468.1 - 4.4e-34 117.0 0.0 9.4e-34 116.0 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC39468.1 - 1.1e-23 84.1 0.0 2e-23 83.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC39468.1 - 2.8e-22 79.3 1.4 1.2e-21 77.3 0.0 3.0 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC39468.1 - 4.4e-22 78.7 0.0 6.8e-22 78.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC39468.1 - 3.4e-09 37.1 0.3 3.8e-08 33.8 0.0 2.9 3 0 0 3 3 2 1 Ketoacyl-synthetase C-terminal extension Methyltransf_23 PF13489.6 EGC39468.1 - 3.4e-09 36.7 0.0 7.9e-09 35.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.6 EGC39468.1 - 2.4e-07 31.9 0.0 8.2e-07 30.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.23 EGC39468.1 - 3.5e-05 23.3 0.2 8e-05 22.1 0.2 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGC39468.1 - 0.002 18.7 0.0 0.0059 17.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC39468.1 - 0.1 12.4 0.0 0.1 12.4 0.0 3.1 3 0 0 3 3 3 0 Methyltransferase domain LktC PF06261.11 EGC39469.1 - 0.021 14.8 0.1 0.031 14.2 0.1 1.3 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC AAA PF00004.29 EGC39470.1 - 3.1e-41 140.9 0.0 5.9e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC39470.1 - 6.9e-11 41.8 0.0 1.5e-10 40.7 0.0 1.6 1 0 0 1 1 1 1 AAA+ lid domain AAA_5 PF07728.14 EGC39470.1 - 2.6e-05 24.2 0.0 0.00011 22.2 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGC39470.1 - 0.00025 21.2 0.0 0.0012 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.6 EGC39470.1 - 0.00028 21.2 0.0 0.024 14.9 0.0 2.4 1 1 1 2 2 2 1 AAA domain DUF815 PF05673.13 EGC39470.1 - 0.0011 18.2 0.0 0.0019 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.6 EGC39470.1 - 0.0014 19.0 0.1 0.015 15.7 0.0 2.2 1 1 1 2 2 2 1 AAA ATPase domain RNA_helicase PF00910.22 EGC39470.1 - 0.0036 17.7 0.0 0.0088 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase RuvB_N PF05496.12 EGC39470.1 - 0.0041 16.9 0.0 0.011 15.4 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGC39470.1 - 0.0042 17.3 0.0 0.0073 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_7 PF12775.7 EGC39470.1 - 0.017 14.6 0.0 0.046 13.2 0.0 1.7 1 1 0 1 1 1 0 P-loop containing dynein motor region Mg_chelatase PF01078.21 EGC39470.1 - 0.028 13.8 0.0 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.13 EGC39470.1 - 0.032 13.4 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 TIP49 P-loop domain AAA_28 PF13521.6 EGC39470.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.6 EGC39470.1 - 0.041 13.6 0.1 0.27 11.0 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_3 PF07726.11 EGC39470.1 - 0.049 13.5 0.0 0.095 12.6 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC39470.1 - 0.088 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain ATPase_2 PF01637.18 EGC39470.1 - 0.12 12.3 0.0 11 5.8 0.0 2.4 1 1 0 2 2 2 0 ATPase domain predominantly from Archaea Zeta_toxin PF06414.12 EGC39470.1 - 0.17 11.1 0.0 0.38 10.0 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.17 EGC39470.1 - 0.21 11.3 0.0 0.36 10.5 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein RNase_Zc3h12a PF11977.8 EGC39471.1 - 9e-24 84.0 0.2 2.2e-23 82.8 0.2 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain DUF5615 PF18480.1 EGC39471.1 - 0.018 14.8 0.1 0.045 13.5 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF5615) FNIP PF05725.12 EGC39472.1 - 2.6e-50 168.3 70.4 1.6e-12 47.3 2.7 12.7 11 2 2 13 13 13 8 FNIP Repeat Pkinase PF00069.25 EGC39472.1 - 5.3e-29 101.4 4.7 5.8e-25 88.1 1.8 3.0 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39472.1 - 1.1e-13 51.1 0.2 2.5e-13 49.9 0.2 1.5 2 0 0 2 2 2 1 Protein tyrosine kinase MATH PF00917.26 EGC39472.1 - 1.1e-10 41.6 2.9 0.0007 19.7 1.9 3.0 2 0 0 2 2 2 2 MATH domain Kdo PF06293.14 EGC39472.1 - 0.0042 16.5 0.0 0.0082 15.5 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC39472.1 - 0.0045 16.3 0.0 0.012 14.9 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.23 EGC39472.1 - 0.0097 15.9 0.0 0.015 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC39472.1 - 0.012 14.5 0.1 0.021 13.6 0.1 1.3 1 0 0 1 1 1 0 Fungal protein kinase MIT_C PF16565.5 EGC39473.1 - 5.9e-55 185.1 0.3 1.1e-54 184.2 0.3 1.5 1 0 0 1 1 1 1 Phospholipase D-like domain at C-terminus of MIT MIT PF04212.18 EGC39473.1 - 3.1e-21 75.2 3.2 5.4e-21 74.4 3.2 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Orthopox_F8 PF05886.11 EGC39473.1 - 4.1 7.6 5.6 10 6.3 5.6 1.6 1 0 0 1 1 1 0 Orthopoxvirus F8 protein Inositol_P PF00459.25 EGC39474.1 - 3e-39 135.2 0.0 4.1e-39 134.7 0.0 1.1 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_2b PF00587.25 EGC39475.1 - 5.1e-34 117.8 4.0 1.1e-33 116.7 4.0 1.6 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.20 EGC39475.1 - 0.0003 20.9 0.1 0.00093 19.3 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain CBM_14 PF01607.24 EGC39477.1 - 2e-07 31.0 5.5 3.3e-07 30.3 5.5 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ras PF00071.22 EGC39478.1 - 1.8e-46 157.7 0.3 2.1e-46 157.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39478.1 - 4.3e-15 56.0 0.0 5.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39478.1 - 7.5e-10 38.5 0.0 8.8e-10 38.3 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC39478.1 - 1.2e-09 38.0 0.7 3.9e-07 29.8 0.1 2.2 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain RsgA_GTPase PF03193.16 EGC39478.1 - 4e-05 23.6 0.2 0.0056 16.6 0.0 2.2 1 1 1 2 2 2 2 RsgA GTPase MMR_HSR1 PF01926.23 EGC39478.1 - 0.0002 21.4 0.1 0.00029 20.9 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.6 EGC39478.1 - 0.0064 16.5 0.0 0.011 15.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.20 EGC39478.1 - 0.008 15.4 0.0 0.01 15.0 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit TniB PF05621.11 EGC39478.1 - 0.024 14.0 0.1 0.075 12.4 0.0 1.9 2 0 0 2 2 2 0 Bacterial TniB protein AAA_7 PF12775.7 EGC39478.1 - 0.14 11.7 0.0 0.39 10.2 0.0 1.7 2 0 0 2 2 2 0 P-loop containing dynein motor region Peptidase_M28 PF04389.17 EGC39479.1 - 4.1e-10 39.7 0.0 1.2e-09 38.2 0.0 1.8 2 0 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.15 EGC39479.1 - 0.0057 16.1 1.6 0.012 15.0 0.0 2.1 2 0 0 2 2 2 1 Nicastrin Ctr PF04145.15 EGC39479.1 - 0.0062 17.2 0.4 0.013 16.1 0.4 1.5 1 0 0 1 1 1 1 Ctr copper transporter family Pex26 PF07163.12 EGC39479.1 - 0.053 12.8 0.1 0.092 12.0 0.1 1.3 1 0 0 1 1 1 0 Pex26 protein DUF16 PF01519.16 EGC39480.1 - 0.25 11.9 3.5 1.7 9.2 3.5 2.0 1 1 0 1 1 1 0 Protein of unknown function DUF16 C2 PF00168.30 EGC39481.1 - 0.0024 18.1 0.2 0.011 15.9 0.0 2.2 2 0 0 2 2 2 1 C2 domain Endotoxin_N PF03945.14 EGC39482.1 - 6.3e-08 32.6 0.1 1.4e-05 25.0 0.1 2.3 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain BSP_II PF05432.11 EGC39483.1 - 0.0034 17.1 22.0 0.0037 17.0 22.0 1.0 1 0 0 1 1 1 1 Bone sialoprotein II (BSP-II) Presenilin PF01080.17 EGC39483.1 - 0.16 10.7 11.1 0.18 10.6 11.1 1.1 1 0 0 1 1 1 0 Presenilin DUF4820 PF16091.5 EGC39483.1 - 0.24 10.7 6.9 0.32 10.3 6.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4820) NOA36 PF06524.12 EGC39483.1 - 0.41 9.9 11.4 0.53 9.6 11.4 1.2 1 0 0 1 1 1 0 NOA36 protein SLC12 PF03522.15 EGC39483.1 - 0.64 9.0 16.2 0.71 8.8 16.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Gti1_Pac2 PF09729.9 EGC39483.1 - 0.77 9.8 16.3 0.93 9.6 16.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Zip PF02535.22 EGC39483.1 - 1.8 7.7 10.1 2.1 7.5 10.1 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Menin PF05053.13 EGC39483.1 - 2.9 6.1 18.0 3.4 5.9 18.0 1.1 1 0 0 1 1 1 0 Menin NPR3 PF03666.13 EGC39483.1 - 2.9 6.6 18.7 3.4 6.4 18.7 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 FAM60A PF15396.6 EGC39483.1 - 3.2 7.7 14.8 4.1 7.4 14.8 1.1 1 0 0 1 1 1 0 Protein Family FAM60A ALMT PF11744.8 EGC39483.1 - 4 6.2 15.7 4.8 5.9 15.7 1.0 1 0 0 1 1 1 0 Aluminium activated malate transporter DUF2076 PF09849.9 EGC39483.1 - 4.4 7.3 18.1 5.4 7.0 18.1 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) V_ATPase_I PF01496.19 EGC39483.1 - 6.2 4.6 12.8 7.4 4.4 12.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family CSG2 PF16965.5 EGC39483.1 - 7.8 5.3 8.5 9.5 5.1 8.5 1.2 1 0 0 1 1 1 0 Ceramide synthase regulator Erf4 PF10256.9 EGC39484.1 - 5.6e-06 26.4 7.0 6.5e-05 23.0 0.8 2.3 1 1 1 2 2 2 2 Golgin subfamily A member 7/ERF4 family Claudin_2 PF13903.6 EGC39484.1 - 1e-05 25.4 0.8 1e-05 25.4 0.8 1.4 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4199 PF13858.6 EGC39484.1 - 0.0016 18.8 6.7 0.0016 18.8 6.7 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) Pox_A14 PF05767.12 EGC39484.1 - 0.19 11.9 7.0 1.2 9.3 7.0 2.0 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 PMT_4TMC PF16192.5 EGC39484.1 - 0.24 11.0 6.1 3.3 7.3 6.1 2.2 1 1 0 1 1 1 0 C-terminal four TMM region of protein-O-mannosyltransferase DHHC PF01529.20 EGC39484.1 - 0.37 10.9 6.3 0.61 10.2 6.3 1.4 1 0 0 1 1 1 0 DHHC palmitoyltransferase Ninjurin PF04923.12 EGC39484.1 - 0.47 10.4 6.3 0.64 10.0 5.7 1.5 1 1 1 2 2 2 0 Ninjurin Cadherin_C_2 PF16492.5 EGC39484.1 - 0.55 11.0 9.1 39 5.1 9.1 2.3 1 1 0 1 1 1 0 Cadherin cytoplasmic C-terminal DUF4013 PF13197.6 EGC39484.1 - 1.3 8.8 11.1 1.5 8.6 10.6 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4013) PCNA_C PF02747.15 EGC39485.1 - 2.1e-05 24.7 0.6 3e-05 24.2 0.6 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain PI-PLC-X PF00388.19 EGC39488.1 - 1.2e-57 193.6 0.0 2.8e-57 192.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.19 EGC39488.1 - 1.4e-35 122.1 0.0 4.2e-35 120.5 0.0 1.9 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.30 EGC39488.1 - 2e-19 69.8 0.0 3e-18 66.0 0.0 2.5 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.11 EGC39488.1 - 0.0007 20.0 0.2 0.0019 18.7 0.2 1.7 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.6 EGC39488.1 - 0.031 14.1 0.4 0.031 14.1 0.4 2.5 3 0 0 3 3 3 0 EF-hand domain pair EF-hand_7 PF13499.6 EGC39488.1 - 0.088 13.3 2.0 0.1 13.1 0.2 2.1 2 0 0 2 2 2 0 EF-hand domain pair PH_12 PF16457.5 EGC39488.1 - 1.3 9.5 6.2 0.53 10.8 0.3 2.6 2 0 0 2 2 2 0 Pleckstrin homology domain Cytochrom_B558a PF05038.13 EGC39489.1 - 0.28 10.8 4.8 6.3 6.3 0.1 2.1 1 1 1 2 2 2 0 Cytochrome Cytochrome b558 alpha-subunit Cytidylate_kin PF02224.18 EGC39490.1 - 0.029 14.1 0.0 0.055 13.2 0.0 1.4 1 0 0 1 1 1 0 Cytidylate kinase AAA_14 PF13173.6 EGC39490.1 - 0.036 14.1 2.1 0.1 12.6 0.0 2.6 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC39490.1 - 5.6 7.5 8.2 0.33 11.5 1.1 2.7 2 2 1 3 3 3 0 AAA domain Patatin PF01734.22 EGC39491.1 - 5.4e-14 52.8 0.4 8.3e-13 49.0 0.4 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase PH_11 PF15413.6 EGC39491.1 - 2.4e-06 27.9 5.2 5.3e-06 26.8 5.2 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.29 EGC39491.1 - 0.00012 22.6 7.0 0.00032 21.1 7.0 1.8 1 0 0 1 1 1 1 PH domain zf-CCHH PF10283.9 EGC39492.1 - 1.1e-10 41.3 3.9 2.1e-10 40.4 3.9 1.5 1 0 0 1 1 1 1 PBZ domain FHA_2 PF17913.1 EGC39492.1 - 2.2e-08 34.2 0.0 9.2e-08 32.2 0.0 2.1 1 0 0 1 1 1 1 FHA domain Macro PF01661.21 EGC39492.1 - 0.062 13.3 0.0 0.2 11.7 0.0 2.0 2 0 0 2 2 2 0 Macro domain BSP_II PF05432.11 EGC39492.1 - 0.075 12.7 24.4 0.12 12.1 24.4 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) FHA PF00498.26 EGC39492.1 - 0.56 10.6 4.2 0.59 10.5 0.1 2.6 2 0 0 2 2 2 0 FHA domain SprA-related PF12118.8 EGC39492.1 - 2.3 7.3 24.4 3.6 6.6 24.4 1.2 1 0 0 1 1 1 0 SprA-related family HAD_2 PF13419.6 EGC39493.1 - 1.8e-09 38.0 0.1 2.7e-09 37.4 0.1 1.3 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.26 EGC39493.1 - 2.1e-05 24.9 0.0 0.0026 18.1 0.0 2.1 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.6 EGC39493.1 - 0.0083 16.2 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.7 EGC39493.1 - 0.032 14.1 0.1 0.97 9.3 0.1 2.2 1 1 0 1 1 1 0 Acid Phosphatase LRR_6 PF13516.6 EGC39494.1 - 2.2e-46 152.0 72.6 3.5e-06 26.6 0.2 17.6 18 0 0 18 18 18 13 Leucine Rich repeat LRR_1 PF00560.33 EGC39494.1 - 0.0023 18.2 55.1 1.8 9.4 0.2 15.3 15 2 0 15 15 15 1 Leucine Rich Repeat LRR_4 PF12799.7 EGC39494.1 - 0.014 15.8 0.4 0.014 15.8 0.4 11.9 6 5 7 13 13 13 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC39494.1 - 0.03 14.1 71.9 0.14 12.0 3.0 12.0 4 3 9 13 13 13 0 Leucine rich repeat ARID PF01388.21 EGC39495.1 - 0.061 14.0 0.1 0.07 13.8 0.1 1.2 1 1 0 1 1 1 0 ARID/BRIGHT DNA binding domain HSP70 PF00012.20 EGC39496.1 - 6.1e-251 833.8 7.9 7.3e-251 833.6 7.9 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.13 EGC39496.1 - 1.7e-16 60.0 1.4 3e-13 49.3 0.2 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.16 EGC39496.1 - 0.00098 18.9 0.0 0.0057 16.4 0.0 2.3 3 0 0 3 3 3 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.6 EGC39496.1 - 0.002 18.5 5.5 1.9 9.0 0.0 3.9 3 2 0 3 3 3 1 Cell division protein FtsA cwf21 PF08312.12 EGC39496.1 - 0.013 15.6 2.7 0.31 11.2 0.6 2.5 2 0 0 2 2 2 0 cwf21 domain CorA PF01544.18 EGC39496.1 - 4.1 6.6 7.3 17 4.6 7.1 1.9 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein FNIP PF05725.12 EGC39497.1 - 9.1e-39 131.4 47.8 3.5e-07 30.3 0.7 9.1 4 2 5 10 10 10 10 FNIP Repeat DUF2661 PF10860.8 EGC39497.1 - 0.14 12.3 1.8 34 4.6 0.0 4.5 4 2 2 6 6 6 0 Protein of unknown function (DUF2661) GED PF02212.18 EGC39497.1 - 0.96 9.6 4.9 19 5.5 0.0 5.1 5 3 3 9 9 9 0 Dynamin GTPase effector domain RhoGEF PF00621.20 EGC39499.1 - 3.8e-49 167.4 5.9 3.8e-49 167.4 5.9 2.8 4 0 0 4 4 4 1 RhoGEF domain CH PF00307.31 EGC39499.1 - 7.1e-14 51.9 4.1 1.3e-12 47.9 0.1 3.7 3 0 0 3 3 3 1 Calponin homology (CH) domain VHP PF02209.19 EGC39499.1 - 3.6e-13 49.3 5.9 1.1e-12 47.8 5.9 1.9 1 0 0 1 1 1 1 Villin headpiece domain CDC24 PF06395.11 EGC39499.1 - 0.0011 19.2 1.1 0.0029 17.8 0.1 2.4 2 0 0 2 2 2 1 CDC24 Calponin IQ PF00612.27 EGC39499.1 - 0.089 12.6 0.0 0.19 11.6 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif DZR PF12773.7 EGC39502.1 - 5e-05 23.2 11.2 9.5e-05 22.3 11.2 1.5 1 0 0 1 1 1 1 Double zinc ribbon RhoGEF PF00621.20 EGC39503.1 - 1.5e-42 145.9 5.1 1.5e-42 145.9 5.1 2.3 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC39503.1 - 0.0038 17.7 0.8 0.011 16.3 0.1 2.1 1 1 1 2 2 2 1 PH domain PTP_tm PF18861.1 EGC39503.1 - 0.053 13.5 0.4 0.098 12.6 0.4 1.4 1 0 0 1 1 1 0 Transmembrane domain of protein tyrosine phosphatase, receptor type J EIIBC-GUT_N PF03612.14 EGC39503.1 - 0.29 10.9 5.7 0.28 10.9 4.1 1.7 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus TFIIA PF03153.13 EGC39503.1 - 0.54 10.2 20.0 1 9.3 20.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EPL1 PF10513.9 EGC39503.1 - 0.99 9.8 13.3 2.7 8.4 13.3 1.8 1 0 0 1 1 1 0 Enhancer of polycomb-like HemX PF04375.14 EGC39503.1 - 2.2 7.5 22.1 0.2 10.9 17.2 1.7 2 0 0 2 2 2 0 HemX, putative uroporphyrinogen-III C-methyltransferase Cofilin_ADF PF00241.20 EGC39504.1 - 3e-23 81.9 0.0 3.5e-23 81.7 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FNIP PF05725.12 EGC39505.1 - 1.2e-18 67.0 61.0 1e-06 28.8 5.9 10.2 7 3 6 13 13 13 10 FNIP Repeat DDE_Tnp_4 PF13359.6 EGC39506.1 - 3.6e-16 59.2 0.0 6.5e-16 58.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.29 EGC39507.1 - 4.1e-07 30.5 6.7 0.00025 21.5 6.7 2.4 1 1 0 1 1 1 1 PH domain PH_10 PF15411.6 EGC39507.1 - 0.1 12.9 3.3 0.21 11.9 3.3 1.5 1 0 0 1 1 1 0 Pleckstrin homology domain ATP_synt_H PF05493.13 EGC39507.1 - 7.2 7.1 8.4 6.1 7.4 2.1 2.3 2 0 0 2 2 2 0 ATP synthase subunit H FNIP PF05725.12 EGC39508.1 - 1.7e-09 37.7 2.1 1.8e-05 24.8 0.1 2.2 1 1 1 2 2 2 2 FNIP Repeat Ribosomal_S21e PF01249.18 EGC39508.1 - 5.4e-07 29.6 0.0 6.9e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein S21e DUF5096 PF17019.5 EGC39508.1 - 0.068 12.9 0.0 0.08 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF5096) Peptidase_M28 PF04389.17 EGC39509.1 - 1.2e-36 126.2 0.0 1.9e-36 125.7 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.15 EGC39509.1 - 0.009 15.5 0.0 0.016 14.6 0.0 1.4 1 0 0 1 1 1 1 Nicastrin ClpB_D2-small PF10431.9 EGC39509.1 - 0.12 12.5 0.0 1.8 8.7 0.0 2.6 2 0 0 2 2 2 0 C-terminal, D2-small domain, of ClpB protein NmrA PF05368.13 EGC39511.1 - 5.2e-61 206.2 0.0 6.7e-61 205.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC39511.1 - 1.1e-16 61.3 0.0 1.6e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding 3Beta_HSD PF01073.19 EGC39511.1 - 2.1e-07 30.2 0.1 4e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Sacchrp_dh_NADP PF03435.18 EGC39511.1 - 5.9e-06 26.6 0.0 1.1e-05 25.7 0.0 1.5 1 0 0 1 1 1 1 Saccharopine dehydrogenase NADP binding domain Epimerase PF01370.21 EGC39511.1 - 6e-06 25.9 0.2 5.6e-05 22.7 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.10 EGC39511.1 - 0.0017 18.3 0.1 0.0031 17.4 0.1 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.25 EGC39511.1 - 0.025 14.0 0.1 0.045 13.2 0.1 1.4 1 0 0 1 1 1 0 short chain dehydrogenase DXP_reductoisom PF02670.16 EGC39511.1 - 0.071 13.8 0.1 0.12 13.1 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase DUF3910 PF13049.6 EGC39511.1 - 0.087 13.1 0.8 0.67 10.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3910) Methyltransf_31 PF13847.6 EGC39512.1 - 2.1e-16 60.1 0.0 3e-16 59.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC39512.1 - 4.4e-16 59.4 0.0 8.8e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC39512.1 - 1.3e-14 54.1 0.1 5.1e-14 52.2 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.12 EGC39512.1 - 2.9e-14 53.5 0.0 5.2e-14 52.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC39512.1 - 1.2e-10 42.0 0.0 2.6e-10 40.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC39512.1 - 6.1e-09 35.9 0.0 8.5e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC39512.1 - 3.5e-05 23.4 0.0 6.4e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.7 EGC39512.1 - 0.00037 20.5 0.0 0.00063 19.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.12 EGC39512.1 - 0.0017 18.2 0.0 0.0038 17.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_32 PF13679.6 EGC39512.1 - 0.0031 17.5 0.0 0.0064 16.5 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGC39512.1 - 0.0054 16.6 0.0 0.13 12.1 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase CMAS PF02353.20 EGC39512.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase NNMT_PNMT_TEMT PF01234.17 EGC39512.1 - 0.033 13.4 0.1 0.073 12.2 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family PCMT PF01135.19 EGC39512.1 - 0.055 13.2 0.0 0.18 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.12 EGC39513.1 - 8.8e-17 61.5 0.0 1.9e-16 60.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC39513.1 - 1.3e-16 61.0 0.0 2.8e-16 60.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC39513.1 - 4.8e-13 49.2 0.0 7.2e-13 48.6 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC39513.1 - 7.7e-13 48.3 0.0 1.7e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.12 EGC39513.1 - 4.7e-11 43.3 0.0 1.5e-10 41.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC39513.1 - 9.9e-08 32.0 0.0 1.4e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.15 EGC39513.1 - 0.0016 18.3 0.0 0.0049 16.8 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.9 EGC39513.1 - 0.0019 17.9 0.0 0.0033 17.2 0.0 1.4 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_18 PF12847.7 EGC39513.1 - 0.0028 17.6 0.0 0.0045 16.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC39513.1 - 0.0035 16.9 0.0 0.0066 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.12 EGC39513.1 - 0.0037 17.0 0.0 0.0064 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PrmA PF06325.13 EGC39513.1 - 0.0094 15.4 0.0 0.017 14.6 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PCMT PF01135.19 EGC39513.1 - 0.019 14.7 0.0 0.038 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.6 EGC39513.1 - 0.064 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TetR_C_8 PF14278.6 EGC39513.1 - 0.32 11.1 3.8 11 6.2 0.3 2.4 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region PS_Dcarbxylase PF02666.15 EGC39514.1 - 1.6e-60 204.1 0.0 2.1e-60 203.7 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase CD52 PF15116.6 EGC39514.1 - 1.6 8.9 6.4 1.3 9.1 4.3 1.9 2 0 0 2 2 2 0 CAMPATH-1 antigen Dicty_REP PF05086.12 EGC39514.1 - 3.6 5.4 4.4 4.4 5.2 3.9 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PHP PF02811.19 EGC39515.1 - 7.4e-06 26.4 0.0 1.8e-05 25.1 0.0 1.7 1 1 0 1 1 1 1 PHP domain Ost4 PF10215.9 EGC39515.1 - 0.3 11.0 2.5 0.65 9.9 2.5 1.6 1 0 0 1 1 1 0 Oligosaccaryltransferase PHP PF02811.19 EGC39516.1 - 1.7e-05 25.2 0.0 2.8e-05 24.5 0.0 1.6 1 1 0 1 1 1 1 PHP domain Sigma_reg_N PF13800.6 EGC39516.1 - 0.12 12.7 6.5 0.19 12.0 1.2 2.5 2 1 0 2 2 2 0 Sigma factor regulator N-terminal VWC PF00093.18 EGC39518.1 - 0.0048 17.2 172.0 0.0049 17.2 6.9 10.6 8 3 1 10 10 10 7 von Willebrand factor type C domain FNIP PF05725.12 EGC39519.1 - 9.3e-84 275.4 40.3 1.4e-13 50.8 2.0 9.1 7 2 0 9 9 9 9 FNIP Repeat DUF1769 PF08588.10 EGC39519.1 - 1.2e-08 35.1 11.0 0.7 10.1 0.1 9.3 8 2 2 10 10 10 4 Protein of unknown function (DUF1769) Phage_min_tail PF05939.13 EGC39519.1 - 0.14 12.6 0.0 34 4.9 0.0 4.0 3 1 3 6 6 6 0 Phage minor tail protein RhoGEF PF00621.20 EGC39520.1 - 3.7e-48 164.2 3.2 3.7e-48 164.2 3.2 2.7 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC39520.1 - 4.3e-19 69.0 4.9 2.2e-12 47.4 0.1 3.7 3 1 0 3 3 3 2 PH domain IQ PF00612.27 EGC39520.1 - 0.025 14.4 11.7 0.048 13.5 0.2 3.8 4 0 0 4 4 4 0 IQ calmodulin-binding motif PH_11 PF15413.6 EGC39520.1 - 6.6 7.2 12.0 0.82 10.1 0.2 4.2 3 2 1 4 4 4 0 Pleckstrin homology domain Med13_N PF11597.8 EGC39521.1 - 0.0095 15.4 0.3 3 7.1 0.1 2.3 2 0 0 2 2 2 2 Mediator complex subunit 13 N-terminal Nup35_RRM PF05172.13 EGC39522.1 - 1.1e-09 38.2 1.3 1.5e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.6 EGC39522.1 - 3.1e-08 33.5 0.0 5.5e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif PfkB PF00294.24 EGC39522.1 - 0.028 13.7 0.2 0.035 13.4 0.2 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase Zip PF02535.22 EGC39522.1 - 0.083 12.1 0.1 0.12 11.6 0.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DUF2967 PF11179.8 EGC39522.1 - 0.48 8.5 4.4 0.54 8.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) TFIIA PF03153.13 EGC39522.1 - 0.49 10.3 14.9 0.61 10.0 14.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_7 PF03492.15 EGC39524.1 - 2.2e-17 63.3 11.9 1.3e-08 34.4 0.7 3.1 1 1 1 2 2 2 2 SAM dependent carboxyl methyltransferase Methyltransf_25 PF13649.6 EGC39524.1 - 0.0084 16.8 0.0 1.4 9.6 0.0 2.6 2 1 0 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.12 EGC39524.1 - 0.011 16.3 0.0 0.028 15.1 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain Cor1 PF04803.12 EGC39525.1 - 0.34 11.1 8.8 0.83 9.9 8.8 1.6 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region Fib_alpha PF08702.10 EGC39525.1 - 1.7 8.8 7.9 1 9.6 5.0 2.0 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Dicty_CTDC PF00526.18 EGC39526.1 - 0.0045 16.8 0.9 0.0045 16.8 0.9 9.9 9 2 0 9 9 9 4 Dictyostelium (slime mold) repeat DUF4761 PF15958.5 EGC39526.1 - 0.14 12.3 0.3 25 5.1 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4761) TnpB_IS66 PF05717.13 EGC39527.1 - 7.7 6.5 20.0 41 4.2 0.4 5.2 1 1 3 5 5 5 0 IS66 Orf2 like protein Spin-Ssty PF02513.17 EGC39528.1 - 0.28 11.0 22.4 9.5 6.0 0.3 5.4 3 2 3 6 6 6 0 Spin/Ssty Family TraB PF01963.17 EGC39529.1 - 1.8e-06 28.0 0.0 3.7e-06 27.0 0.0 1.5 2 0 0 2 2 2 1 TraB family LRR_6 PF13516.6 EGC39530.1 - 3e-17 61.2 15.4 0.033 14.2 0.0 9.6 9 0 0 9 9 9 6 Leucine Rich repeat Carm_PH PF17888.1 EGC39530.1 - 0.00054 20.3 0.2 0.0026 18.1 0.2 2.2 1 0 0 1 1 1 1 Carmil pleckstrin homology domain Myb_DNA-binding PF00249.31 EGC39531.1 - 8.4e-49 163.5 15.7 1.8e-18 66.5 2.2 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.6 EGC39531.1 - 5.6e-37 125.8 13.5 1.3e-19 70.2 1.6 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_7 PF15963.5 EGC39531.1 - 4.8e-05 23.2 1.4 0.028 14.3 0.1 3.0 1 1 2 3 3 3 1 Myb DNA-binding like Rap1_C PF11626.8 EGC39531.1 - 9.4e-05 22.4 2.0 0.016 15.3 0.2 2.3 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain SLIDE PF09111.10 EGC39531.1 - 0.00014 21.9 0.5 0.18 11.9 0.0 2.9 1 1 2 3 3 3 2 SLIDE Myb_DNA-bind_4 PF13837.6 EGC39531.1 - 0.00067 20.0 12.2 1.6 9.2 0.5 3.8 2 1 1 3 3 3 3 Myb/SANT-like DNA-binding domain SANT_DAMP1_like PF16282.5 EGC39531.1 - 0.007 16.5 1.1 0.13 12.4 0.0 2.3 1 1 1 2 2 2 1 SANT/Myb-like domain of DAMP1 DUF5591 PF17884.1 EGC39531.1 - 0.044 13.6 0.9 0.42 10.5 0.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5591) Dynein_light PF01221.18 EGC39531.1 - 0.082 13.2 5.6 1.4 9.2 0.1 3.0 1 1 2 3 3 3 0 Dynein light chain type 1 DUF1539 PF07560.11 EGC39531.1 - 0.2 11.7 5.7 3.5 7.7 3.3 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) Myb_DNA-bind_2 PF08914.11 EGC39531.1 - 0.49 10.6 6.2 7.9 6.7 0.0 3.6 2 2 2 4 4 4 0 Rap1 Myb domain DUP PF00674.18 EGC39531.1 - 2 8.6 5.7 6 7.1 0.3 3.2 2 2 0 3 3 3 0 DUP family Macoilin PF09726.9 EGC39534.1 - 0.014 14.0 15.3 0.014 14.0 15.3 1.1 1 0 0 1 1 1 0 Macoilin family RPOL_N PF14700.6 EGC39534.1 - 0.03 13.7 6.4 0.048 13.1 6.4 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal GEMIN8 PF15348.6 EGC39534.1 - 0.91 9.8 15.1 1.9 8.7 15.1 1.5 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Presenilin PF01080.17 EGC39534.1 - 3.3 6.4 12.9 4.7 5.9 12.9 1.2 1 0 0 1 1 1 0 Presenilin ALMT PF11744.8 EGC39534.1 - 3.8 6.2 17.4 6.3 5.5 17.4 1.4 1 0 0 1 1 1 0 Aluminium activated malate transporter Zip PF02535.22 EGC39534.1 - 6.5 5.9 13.0 9.8 5.3 13.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter PNISR PF15996.5 EGC39534.1 - 8.6 6.6 14.6 15 5.8 14.6 1.3 1 0 0 1 1 1 0 Arginine/serine-rich protein PNISR DCD PF06559.11 EGC39535.1 - 0.047 12.5 0.4 0.064 12.0 0.4 1.3 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) DUF1664 PF07889.12 EGC39535.1 - 0.73 9.9 5.1 1.2 9.1 1.4 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) FAD_binding_1 PF00667.20 EGC39536.1 - 3.2e-43 147.9 0.1 6.3e-43 146.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.25 EGC39536.1 - 3.4e-27 95.4 0.1 2.2e-26 92.8 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.21 EGC39536.1 - 9.4e-20 71.3 0.0 3.1e-19 69.6 0.0 2.0 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.7 EGC39536.1 - 0.00025 21.3 0.0 0.001 19.3 0.0 2.1 2 0 0 2 2 2 1 Flavodoxin domain NAD_binding_6 PF08030.12 EGC39536.1 - 0.00067 19.8 0.1 0.0092 16.1 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain LON_substr_bdg PF02190.16 EGC39536.1 - 0.13 12.1 0.1 1.6 8.6 0.0 2.2 2 0 0 2 2 2 0 ATP-dependent protease La (LON) substrate-binding domain SPG48 PF14764.6 EGC39537.1 - 2.7e-33 114.9 5.2 8.6e-33 113.3 3.6 2.8 2 0 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Gemini_AL2 PF01440.16 EGC39537.1 - 0.01 16.3 1.0 0.028 14.9 1.0 1.7 1 0 0 1 1 1 0 Geminivirus AL2 protein DUF4834 PF16118.5 EGC39538.1 - 0.091 13.7 1.5 0.14 13.1 1.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF4083 PF13314.6 EGC39538.1 - 0.15 12.0 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4083) HCO3_cotransp PF00955.21 EGC39538.1 - 0.16 10.7 1.6 0.21 10.4 1.6 1.1 1 0 0 1 1 1 0 HCO3- transporter family CPW_WPC PF09717.10 EGC39538.1 - 4.4 8.3 51.2 22 6.1 0.8 10.0 2 1 3 6 6 6 0 Plasmodium falciparum domain of unknown function (CPW_WPC) DUF1664 PF07889.12 EGC39539.1 - 0.0022 18.0 5.0 0.0022 18.0 5.0 4.5 3 1 2 5 5 5 2 Protein of unknown function (DUF1664) Cnd1 PF12717.7 EGC39540.1 - 1.2e-42 145.7 0.0 1.2e-42 145.7 0.0 6.9 6 1 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.7 EGC39540.1 - 2.6e-22 79.4 3.1 2.6e-22 79.4 3.1 5.3 7 1 0 7 7 7 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.6 EGC39540.1 - 0.00016 22.0 0.1 0.26 11.7 0.0 4.4 4 1 0 4 4 4 1 HEAT repeats HEAT PF02985.22 EGC39540.1 - 0.00048 20.2 1.1 7.1 7.2 0.1 5.2 5 0 0 5 5 5 1 HEAT repeat RTP1_C1 PF10363.9 EGC39540.1 - 0.0051 17.0 2.7 9.4 6.5 0.0 4.8 3 1 1 4 4 4 2 Required for nuclear transport of RNA pol II C-terminus 1 QueF PF14489.6 EGC39540.1 - 0.0077 16.4 2.0 1.9 8.7 0.0 3.6 3 0 0 3 3 3 1 QueF-like protein HisKA_2 PF07568.12 EGC39540.1 - 2.8 8.1 6.0 3.6 7.7 0.7 3.7 3 0 0 3 3 3 0 Histidine kinase CPBP PF02517.16 EGC39541.1 - 1.3e-14 54.3 5.1 3.4e-14 53.0 5.1 1.7 1 0 0 1 1 1 1 CPBP intramembrane metalloprotease FAM60A PF15396.6 EGC39541.1 - 0.43 10.6 7.2 0.13 12.2 2.0 2.1 2 0 0 2 2 2 0 Protein Family FAM60A ketoacyl-synt PF00109.26 EGC39542.1 - 1.8e-66 224.3 0.0 2.9e-66 223.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC39542.1 - 1e-44 153.4 0.0 1.6e-44 152.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGC39542.1 - 5e-38 130.7 0.0 9.1e-38 129.9 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC39542.1 - 5.1e-31 107.1 0.0 1.1e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC39542.1 - 5.2e-30 104.7 0.4 3.5e-23 82.5 0.0 3.8 4 0 0 4 4 4 2 KR domain KAsynt_C_assoc PF16197.5 EGC39542.1 - 1.3e-15 57.8 0.2 6.2e-15 55.6 0.2 2.3 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension PS-DH PF14765.6 EGC39542.1 - 1.6e-13 50.6 0.0 2.6e-13 49.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.6 EGC39542.1 - 3.9e-12 47.4 0.0 2.2e-11 44.9 0.0 2.4 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Epimerase PF01370.21 EGC39542.1 - 3.4e-07 30.0 0.1 4.2e-06 26.4 0.0 2.5 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.25 EGC39542.1 - 6.4e-07 29.6 0.0 1.7e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site adh_short PF00106.25 EGC39542.1 - 1e-06 28.4 2.7 8.1e-05 22.2 0.0 3.4 5 0 0 5 5 5 1 short chain dehydrogenase ADH_zinc_N PF00107.26 EGC39542.1 - 1.1e-06 28.6 0.0 4.6e-06 26.6 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGC39542.1 - 1.5e-06 28.8 0.0 1.5e-06 28.8 0.0 3.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC39542.1 - 1.7e-06 28.0 0.1 0.00067 19.5 0.0 3.4 4 0 0 4 4 4 1 Methyltransferase domain ADH_N PF08240.12 EGC39542.1 - 2e-06 27.6 0.1 8.1e-06 25.7 0.1 2.1 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.23 EGC39542.1 - 0.00062 19.2 0.1 0.0013 18.2 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.24 EGC39542.1 - 0.00088 19.7 0.1 0.15 12.5 0.0 3.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain GDP_Man_Dehyd PF16363.5 EGC39542.1 - 0.015 14.7 1.4 1.9 7.8 0.1 3.1 3 0 0 3 3 3 0 GDP-mannose 4,6 dehydratase adh_short_C2 PF13561.6 EGC39542.1 - 0.025 14.1 0.0 0.07 12.7 0.0 1.7 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase Methyltransf_31 PF13847.6 EGC39542.1 - 0.089 12.6 0.9 0.85 9.4 0.4 3.1 2 1 0 2 2 1 0 Methyltransferase domain MeaB PF03308.16 EGC39542.1 - 0.27 10.2 0.3 1.4 7.8 0.0 2.0 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Secretin_N_2 PF07655.13 EGC39542.1 - 2 9.0 17.2 2.2 8.9 9.1 3.2 2 0 0 2 2 2 0 Secretin N-terminal domain DUF4282 PF14110.6 EGC39543.1 - 3.1e-15 56.7 8.5 3.8e-15 56.4 8.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) DUF4834 PF16118.5 EGC39543.1 - 0.068 14.1 0.1 0.068 14.1 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Spt20 PF12090.8 EGC39543.1 - 0.17 11.5 10.3 0.21 11.2 10.3 1.1 1 0 0 1 1 1 0 Spt20 family polyprenyl_synt PF00348.17 EGC39544.1 - 2.1e-91 305.5 0.0 2.5e-91 305.3 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Aminotran_5 PF00266.19 EGC39545.1 - 3.1e-93 312.7 0.0 3.7e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.21 EGC39545.1 - 2.5e-08 33.5 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.17 EGC39545.1 - 5.8e-06 25.8 0.1 1e-05 25.1 0.1 1.4 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.20 EGC39545.1 - 0.00057 18.5 0.0 0.00091 17.9 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Pyridoxal_deC PF00282.19 EGC39545.1 - 0.016 14.0 0.0 0.031 13.0 0.0 1.5 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain Ribosomal_S24e PF01282.19 EGC39545.1 - 0.08 12.9 0.1 0.18 11.8 0.1 1.5 1 0 0 1 1 1 0 Ribosomal protein S24e MIP PF00230.20 EGC39546.1 - 1.1e-50 172.5 13.4 1.4e-50 172.1 13.4 1.0 1 0 0 1 1 1 1 Major intrinsic protein YhfT PF10797.9 EGC39546.1 - 0.00049 19.3 0.5 0.00049 19.3 0.5 1.9 2 1 0 2 2 2 1 Protein of unknown function Peptidase_M20 PF01546.28 EGC39547.1 - 7.5e-23 81.3 0.0 2.4e-22 79.7 0.0 1.7 1 1 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.14 EGC39547.1 - 5e-11 42.5 0.0 1.2e-10 41.3 0.0 1.7 1 0 0 1 1 1 1 Peptidase dimerisation domain Sulfate_transp PF00916.20 EGC39550.1 - 7.8e-94 314.5 27.6 1.2e-93 313.9 27.6 1.3 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGC39550.1 - 8.1e-18 64.2 0.2 1.9e-17 63.0 0.2 1.7 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGC39550.1 - 0.012 16.0 3.6 0.012 16.0 3.6 3.2 3 0 0 3 3 3 0 Molybdate transporter of MFS superfamily DUF3525 PF12039.8 EGC39550.1 - 0.027 13.2 0.1 0.027 13.2 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Sulfate_transp PF00916.20 EGC39551.1 - 4.3e-94 315.4 28.0 4.3e-94 315.4 28.0 1.7 2 0 0 2 2 2 1 Sulfate permease family STAS PF01740.21 EGC39551.1 - 3.8e-20 71.7 0.5 2.4e-19 69.1 0.3 2.5 1 1 1 2 2 2 1 STAS domain GPI2 PF06432.11 EGC39551.1 - 0.004 16.6 0.0 0.13 11.7 0.0 3.1 2 1 1 3 3 3 1 Phosphatidylinositol N-acetylglucosaminyltransferase MFS_MOT1 PF16983.5 EGC39551.1 - 0.0062 16.9 3.4 0.0062 16.9 3.4 3.6 4 1 0 4 4 4 1 Molybdate transporter of MFS superfamily TSSC4 PF15264.6 EGC39551.1 - 0.072 13.4 0.2 0.14 12.4 0.2 1.5 1 0 0 1 1 1 0 Tumour suppressing sub-chromosomal transferable candidate 4 STAS_2 PF13466.6 EGC39551.1 - 0.17 12.3 0.0 0.26 11.7 0.0 1.3 1 0 0 1 1 1 0 STAS domain DUF2919 PF11143.8 EGC39551.1 - 3.1 8.1 5.5 0.49 10.7 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF2919) CBM_14 PF01607.24 EGC39552.1 - 0.17 12.0 4.6 0.13 12.4 1.5 1.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain PMM PF03332.13 EGC39553.1 - 3.1e-100 334.5 3.7 3.6e-100 334.3 3.7 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.12 EGC39553.1 - 2.9e-06 27.2 0.0 6.2e-06 26.1 0.0 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF600 PF04634.12 EGC39553.1 - 0.032 14.3 0.0 0.063 13.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF600 S6PP PF05116.13 EGC39553.1 - 0.077 12.5 0.0 1 8.9 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase Pkinase PF00069.25 EGC39554.1 - 1.1e-65 221.6 0.0 5.1e-65 219.5 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Calpain_III PF01067.22 EGC39554.1 - 3e-58 196.1 2.8 2.6e-16 60.1 0.1 4.7 4 0 0 4 4 4 4 Calpain large subunit, domain III Pkinase_Tyr PF07714.17 EGC39554.1 - 1.8e-49 168.4 0.0 7.1e-49 166.4 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC39554.1 - 0.0003 19.7 1.7 0.00036 19.4 0.0 1.8 2 0 0 2 2 2 1 Fungal protein kinase Abi_2 PF07751.11 EGC39554.1 - 0.066 13.5 0.2 0.22 11.7 0.2 1.9 1 0 0 1 1 1 0 Abi-like protein Adaptin_binding PF10199.9 EGC39554.1 - 2.9 8.5 12.4 0.12 13.0 5.3 2.3 2 1 1 3 3 3 0 Alpha and gamma adaptin binding protein p34 DNA_pol_phi PF04931.13 EGC39555.1 - 8.6e-114 381.3 38.9 8.6e-114 381.3 38.9 3.9 2 2 1 3 3 3 1 DNA polymerase phi RNA_pol_3_Rpc31 PF11705.8 EGC39555.1 - 0.00041 20.7 14.3 0.00041 20.7 14.3 3.9 4 1 0 4 4 4 1 DNA-directed RNA polymerase III subunit Rpc31 PhyH PF05721.13 EGC39556.1 - 2.6e-47 161.8 0.0 3e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mito_carr PF00153.27 EGC39558.1 - 2.8e-10 40.0 0.2 5.4e-05 23.0 0.1 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein GST_N PF02798.20 EGC39559.1 - 3.2e-13 49.8 0.1 2.8e-12 46.8 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.6 EGC39559.1 - 4.9e-12 46.1 0.0 1.2e-11 44.9 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.6 EGC39559.1 - 5.1e-11 42.7 0.0 1.1e-10 41.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.25 EGC39559.1 - 7.6e-10 38.9 0.0 1.5e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.6 EGC39559.1 - 5.6e-07 29.5 0.0 1.4e-06 28.2 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.6 EGC39559.1 - 4.3e-06 26.8 0.0 1.8e-05 24.9 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.7 EGC39561.1 - 0.0014 18.5 0.6 0.0057 16.5 0.2 2.0 2 0 0 2 2 2 1 F-box-like DHQ_synthase PF01761.20 EGC39561.1 - 0.013 14.7 0.0 0.026 13.7 0.0 1.5 1 0 0 1 1 1 0 3-dehydroquinate synthase Ribosomal_L26 PF16906.5 EGC39561.1 - 0.073 13.5 0.0 0.18 12.3 0.0 1.7 1 0 0 1 1 1 0 Ribosomal proteins L26 eukaryotic, L24P archaeal IBN_N PF03810.19 EGC39562.1 - 8.7e-09 35.2 0.1 8.7e-09 35.2 0.1 3.1 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.12 EGC39562.1 - 0.0012 18.9 0.6 0.051 13.6 0.0 4.1 3 2 1 4 4 4 1 Exportin 1-like protein Cnd1 PF12717.7 EGC39562.1 - 0.0061 16.6 1.4 0.08 13.0 0.0 3.6 4 0 0 4 4 4 1 non-SMC mitotic condensation complex subunit 1 PRC2_HTH_1 PF18118.1 EGC39562.1 - 0.015 16.1 1.0 0.83 10.5 0.7 2.7 2 0 0 2 2 2 0 Polycomb repressive complex 2 tri-helical domain HEAT_EZ PF13513.6 EGC39562.1 - 0.018 15.6 0.3 20 5.8 0.0 4.0 4 0 0 4 4 4 0 HEAT-like repeat HEAT PF02985.22 EGC39562.1 - 0.065 13.5 0.0 15 6.1 0.0 3.2 2 0 0 2 2 2 0 HEAT repeat RXT2_N PF08595.11 EGC39562.1 - 0.091 12.8 4.6 0.07 13.2 1.3 2.2 2 0 0 2 2 2 0 RXT2-like, N-terminal DUF4611 PF15387.6 EGC39562.1 - 0.99 9.7 7.3 3.6 7.9 7.3 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RIX1 PF08167.12 EGC39562.1 - 1.6 8.4 8.4 1.5 8.5 0.7 3.9 4 0 0 4 4 4 0 rRNA processing/ribosome biogenesis DUF2457 PF10446.9 EGC39562.1 - 3.9 6.5 10.0 5.7 6.0 10.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SET PF00856.28 EGC39563.1 - 1.7e-09 38.3 4.1 1.7e-09 38.3 4.1 2.6 2 2 0 2 2 2 1 SET domain Focal_AT PF03623.13 EGC39563.1 - 0.045 13.7 0.7 0.13 12.2 0.7 1.8 1 0 0 1 1 1 0 Focal adhesion targeting region zf-RING_6 PF14835.6 EGC39563.1 - 3.2 7.7 10.2 1.4 8.9 1.5 2.6 2 0 0 2 2 2 0 zf-RING of BARD1-type protein APAF1_C PF17908.1 EGC39563.1 - 7.6 6.5 12.3 0.8 9.7 3.6 3.4 3 1 1 4 4 4 0 APAF-1 helical domain WD40 PF00400.32 EGC39565.1 - 7.9e-23 80.3 7.2 3.8e-05 24.4 0.0 6.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC39565.1 - 3.4e-13 49.7 0.1 0.01 16.1 0.0 4.6 1 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain eIF2A PF08662.11 EGC39565.1 - 0.0013 18.6 0.4 12 5.7 0.0 3.5 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A WD40_like PF17005.5 EGC39565.1 - 0.0017 17.8 0.3 0.48 9.7 0.3 3.0 3 0 0 3 3 3 1 WD40-like domain Ge1_WD40 PF16529.5 EGC39565.1 - 0.0033 16.4 0.0 0.13 11.2 0.0 2.7 3 1 0 3 3 3 1 WD40 region of Ge1, enhancer of mRNA-decapping protein Frtz PF11768.8 EGC39565.1 - 0.0038 15.6 0.0 0.32 9.2 0.0 2.7 3 0 0 3 3 3 1 WD repeat-containing and planar cell polarity effector protein Fritz DUF4221 PF13970.6 EGC39565.1 - 0.0086 15.7 2.5 2 7.9 0.4 2.4 1 1 0 2 2 2 2 Domain of unknown function (DUF4221) DUF5640 PF18692.1 EGC39565.1 - 0.084 12.9 0.7 16 5.6 0.1 2.8 2 1 0 2 2 2 0 Family of unknown function (DUF5640) NAGPA PF09992.9 EGC39565.1 - 0.13 12.5 0.0 0.45 10.7 0.0 1.9 2 0 0 2 2 2 0 Phosphodiester glycosidase IQ PF00612.27 EGC39566.1 - 2.8e-09 35.9 9.5 0.0011 18.6 0.3 3.4 3 0 0 3 3 3 3 IQ calmodulin-binding motif LSM PF01423.22 EGC39567.1 - 1.2e-16 60.2 0.0 1.3e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.6 EGC39567.1 - 0.18 12.0 0.0 0.24 11.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Endotoxin_N PF03945.14 EGC39568.1 - 4.1e-06 26.7 1.2 4.1e-06 26.7 1.2 2.4 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain Syja_N PF02383.18 EGC39569.1 - 1.4e-46 159.3 5.7 1.4e-46 159.3 5.7 2.6 3 0 0 3 3 3 1 SacI homology domain FYVE PF01363.21 EGC39569.1 - 0.0092 16.1 6.4 0.023 14.8 6.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger IBR PF01485.21 EGC39569.1 - 0.03 14.5 5.6 0.089 13.0 5.6 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-AN1 PF01428.16 EGC39569.1 - 3.7 7.8 7.7 9.8 6.4 7.7 1.8 1 0 0 1 1 1 0 AN1-like Zinc finger FYVE_2 PF02318.16 EGC39569.1 - 5 7.4 9.1 0.77 10.0 4.7 1.9 2 0 0 2 2 2 0 FYVE-type zinc finger Sulfate_transp PF00916.20 EGC39570.1 - 2.2e-97 326.2 16.9 3e-97 325.8 16.9 1.2 1 0 0 1 1 1 1 Sulfate permease family STAS PF01740.21 EGC39570.1 - 2.9e-17 62.4 0.1 4.9e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain MFS_MOT1 PF16983.5 EGC39570.1 - 0.0059 17.0 4.2 0.0059 17.0 4.2 3.0 3 0 0 3 3 3 1 Molybdate transporter of MFS superfamily Na_Ca_ex PF01699.24 EGC39571.1 - 7.2e-16 58.5 39.0 5.1e-11 42.8 18.1 4.0 3 1 0 4 4 4 2 Sodium/calcium exchanger protein YccF PF03733.13 EGC39571.1 - 3.2e-14 53.4 16.0 3.2e-14 53.4 16.0 5.1 5 0 0 5 5 5 1 Inner membrane component domain Ashwin PF15323.6 EGC39571.1 - 0.16 12.0 3.4 0.24 11.4 3.4 1.2 1 0 0 1 1 1 0 Developmental protein CDC45 PF02724.14 EGC39572.1 - 0.15 10.3 56.1 0.24 9.7 23.0 2.4 2 0 0 2 2 2 0 CDC45-like protein RNA_pol_Rpc4 PF05132.14 EGC39572.1 - 0.18 12.2 23.6 0.45 10.9 7.4 2.6 2 0 0 2 2 2 0 RNA polymerase III RPC4 Caldesmon PF02029.15 EGC39572.1 - 0.56 8.9 60.0 0.24 10.1 23.8 2.3 2 0 0 2 2 2 0 Caldesmon DUF5308 PF17233.2 EGC39572.1 - 2.6 8.2 10.4 4.3 7.5 1.9 2.5 2 0 0 2 2 2 0 Family of unknown function (DUF5308) DUF2722 PF10846.8 EGC39573.1 - 0.0058 15.6 16.3 0.0058 15.6 16.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2722) DUF4805 PF16063.5 EGC39573.1 - 0.0069 15.8 3.3 1.7 7.9 0.0 2.3 2 0 0 2 2 2 2 Domain of unknown function (DUF4805) Activator_LAG-3 PF11498.8 EGC39573.1 - 0.018 14.1 19.6 0.025 13.6 19.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 TERB2 PF15101.6 EGC39573.1 - 0.018 15.1 7.0 0.038 14.0 7.0 1.5 1 0 0 1 1 1 0 Telomere-associated protein TERB2 CTP_transf_like PF01467.26 EGC39573.1 - 0.037 14.2 1.4 3.1 8.0 0.0 2.9 3 0 0 3 3 3 0 Cytidylyltransferase-like DivIC PF04977.15 EGC39573.1 - 0.22 11.3 10.9 0.65 9.8 10.9 1.8 1 0 0 1 1 1 0 Septum formation initiator DUF3464 PF11947.8 EGC39573.1 - 0.48 10.2 5.7 1.3 8.8 5.7 1.7 1 0 0 1 1 1 0 Photosynthesis affected mutant 68 DUF3371 PF11851.8 EGC39573.1 - 0.6 11.2 9.7 1.4 10.0 9.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) DUF702 PF05142.12 EGC39573.1 - 0.62 10.5 6.6 0.67 10.4 5.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) EIIBC-GUT_N PF03612.14 EGC39573.1 - 1.2 8.8 6.8 1.6 8.4 5.4 1.9 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF4175 PF13779.6 EGC39573.1 - 1.8 6.3 12.8 2.5 5.9 12.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Roughex PF06020.11 EGC39573.1 - 5 6.1 12.8 7.4 5.6 12.8 1.2 1 0 0 1 1 1 0 Drosophila roughex protein Tim17 PF02466.19 EGC39574.1 - 9.7e-18 64.6 2.4 9.7e-18 64.6 2.4 1.5 2 0 0 2 2 2 1 Tim17/Tim22/Tim23/Pmp24 family DUF5518 PF17647.1 EGC39574.1 - 0.64 10.2 8.8 2.8 8.1 2.7 2.9 1 1 1 2 2 2 0 Family of unknown function (DUF5518) FGE-sulfatase PF03781.16 EGC39575.1 - 4.9e-48 164.0 0.2 7e-48 163.5 0.2 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FGE-sulfatase PF03781.16 EGC39576.1 - 2.6e-48 164.9 0.0 3.5e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FGE-sulfatase PF03781.16 EGC39577.1 - 2.1e-50 171.8 2.1 2.6e-50 171.4 2.1 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Tweety PF04906.13 EGC39577.1 - 0.037 12.7 0.0 0.044 12.5 0.0 1.1 1 0 0 1 1 1 0 Tweety DUF5327 PF17261.2 EGC39579.1 - 0.011 16.4 4.5 0.022 15.5 4.5 1.5 1 0 0 1 1 1 0 Family of unknown function (DUF5327) EST1 PF10374.9 EGC39579.1 - 1.4 9.6 6.7 0.85 10.3 3.1 2.4 2 1 0 2 2 2 0 Telomerase activating protein Est1 Band_3_cyto PF07565.13 EGC39579.1 - 5.2 6.8 7.9 18 5.0 3.2 2.1 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Zip PF02535.22 EGC39580.1 - 1.2e-29 103.6 29.2 4.1e-21 75.5 17.7 2.7 1 1 1 2 2 2 2 ZIP Zinc transporter Presenilin PF01080.17 EGC39580.1 - 0.013 14.3 1.9 0.069 11.9 0.2 2.3 2 0 0 2 2 2 0 Presenilin Apolipoprotein PF01442.18 EGC39581.1 - 5.6e-11 42.7 10.1 7.6e-10 39.0 10.1 2.2 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain DUF883 PF05957.13 EGC39581.1 - 1.5e-10 41.5 26.7 0.0028 18.2 4.9 5.0 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF883) YtxH PF12732.7 EGC39581.1 - 2.5e-10 40.7 43.1 0.0073 16.8 4.9 5.4 2 2 2 4 4 4 3 YtxH-like protein Prominin PF05478.11 EGC39581.1 - 3.2e-09 35.3 9.2 4.2e-09 35.0 9.2 1.1 1 0 0 1 1 1 1 Prominin ApoLp-III PF07464.11 EGC39581.1 - 0.00044 20.4 25.6 0.051 13.7 10.7 3.0 1 1 2 3 3 3 3 Apolipophorin-III precursor (apoLp-III) WXG100 PF06013.12 EGC39581.1 - 0.0015 18.7 22.1 0.12 12.7 7.0 4.3 1 1 4 5 5 5 3 Proteins of 100 residues with WXG ApoO PF09769.9 EGC39581.1 - 0.0023 17.9 10.2 2.3 8.2 0.1 4.7 1 1 4 5 5 5 2 Apolipoprotein O FAM184 PF15665.5 EGC39581.1 - 0.029 14.1 18.8 0.032 14.0 11.6 2.4 1 1 1 2 2 2 0 Family with sequence similarity 184, A and B DUF948 PF06103.11 EGC39581.1 - 0.054 13.8 19.9 0.98 9.7 2.3 4.7 1 1 5 6 6 6 0 Bacterial protein of unknown function (DUF948) DBD_Tnp_Hermes PF10683.9 EGC39581.1 - 0.092 12.4 0.4 0.25 11.0 0.4 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain HGAL PF15666.5 EGC39581.1 - 0.13 12.4 1.8 0.35 11.0 0.3 2.2 1 1 0 2 2 2 0 Germinal center-associated lymphoma Exonuc_VII_L PF02601.15 EGC39581.1 - 0.15 11.6 11.4 2.6 7.6 11.4 2.2 1 1 0 1 1 1 0 Exonuclease VII, large subunit DUF1798 PF08807.10 EGC39581.1 - 0.19 11.9 19.0 0.43 10.7 0.6 4.5 1 1 3 4 4 4 0 Bacterial domain of unknown function (DUF1798) Uteroglobin PF01099.17 EGC39581.1 - 0.34 11.3 14.0 7.5 7.0 0.5 4.3 4 1 1 5 5 5 0 Uteroglobin family CtnDOT_TraJ PF07863.11 EGC39581.1 - 0.69 10.6 9.5 1.9 9.2 0.0 4.5 3 3 2 5 5 5 0 Homologues of TraJ from Bacteroides conjugative transposon YlqD PF11068.8 EGC39581.1 - 0.72 10.2 12.2 23 5.4 0.0 3.4 1 1 2 3 3 3 0 YlqD protein DUF3584 PF12128.8 EGC39581.1 - 0.73 7.3 26.7 0.19 9.2 7.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) ApoC-I PF04691.12 EGC39581.1 - 0.76 9.7 19.0 9.4 6.2 1.5 5.2 1 1 5 6 6 6 0 Apolipoprotein C-I (ApoC-1) RRF PF01765.19 EGC39581.1 - 0.8 9.6 34.4 1.8 8.5 10.2 3.9 1 1 4 5 5 5 0 Ribosome recycling factor Nup88 PF10168.9 EGC39581.1 - 1.3 6.7 16.5 0.85 7.3 1.8 2.1 1 1 1 2 2 2 0 Nuclear pore component Chlorosome_CsmC PF11098.8 EGC39581.1 - 1.8 8.5 24.5 0.98 9.4 3.2 4.7 1 1 4 5 5 5 0 Chlorosome envelope protein C OmpH PF03938.14 EGC39581.1 - 2.1 8.7 26.3 47 4.3 8.5 3.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) TMP_2 PF06791.13 EGC39581.1 - 2.1 7.9 14.1 6.8 6.3 5.6 2.4 1 1 1 2 2 2 0 Prophage tail length tape measure protein ATP-synt_J PF04911.12 EGC39581.1 - 2.2 7.9 9.8 6.9 6.3 0.4 4.0 4 0 0 4 4 4 0 ATP synthase j chain PIN_8 PF18476.1 EGC39581.1 - 2.3 8.0 26.7 4.6 7.0 7.8 3.1 1 1 2 3 3 3 0 PIN like domain YbjQ_1 PF01906.17 EGC39581.1 - 2.7 8.7 11.3 5.6 7.7 0.5 4.3 1 1 4 5 5 5 0 Putative heavy-metal-binding p450 PF00067.22 EGC39581.1 - 3.4 6.3 6.2 7.9 5.1 6.1 1.7 1 1 0 1 1 1 0 Cytochrome P450 LMBR1 PF04791.16 EGC39581.1 - 3.8 6.3 10.0 4.6 6.0 10.0 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PhaP_Bmeg PF09602.10 EGC39581.1 - 5.3 6.9 20.3 7 6.5 3.6 3.2 1 1 3 4 4 4 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) ThiF PF00899.21 EGC39582.1 - 2.1e-64 217.2 0.0 3.3e-64 216.6 0.0 1.2 1 0 0 1 1 1 1 ThiF family Rhodanese PF00581.20 EGC39582.1 - 2.7e-06 27.9 0.1 5.8e-06 26.8 0.1 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.16 EGC39582.1 - 0.0019 17.8 0.2 0.0052 16.4 0.2 1.7 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.14 EGC39582.1 - 0.003 17.2 0.7 0.0071 15.9 0.5 1.7 1 1 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain FAD_binding_3 PF01494.19 EGC39582.1 - 0.0041 16.4 0.1 0.0061 15.8 0.1 1.3 1 0 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.20 EGC39582.1 - 0.0052 16.8 0.8 0.021 14.9 0.2 2.3 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.6 EGC39582.1 - 0.018 15.5 0.8 0.15 12.5 0.1 2.3 2 0 0 2 2 2 0 Putative NAD(P)-binding Pyr_redox PF00070.27 EGC39582.1 - 0.031 14.8 1.0 0.13 12.8 0.4 2.4 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.14 EGC39582.1 - 0.043 13.0 0.0 0.073 12.3 0.0 1.5 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Sacchrp_dh_NADP PF03435.18 EGC39582.1 - 0.072 13.3 1.2 0.25 11.6 1.2 1.9 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain NdhM PF10664.9 EGC39582.1 - 0.13 12.5 1.4 4.2 7.7 1.4 2.5 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DAO PF01266.24 EGC39582.1 - 0.27 10.8 3.4 0.43 10.1 3.4 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase GBP PF02263.19 EGC39583.1 - 6.1e-07 29.0 2.3 0.00018 20.9 0.0 2.5 1 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGC39583.1 - 0.00023 21.2 0.1 0.0007 19.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase HSP20 PF00011.21 EGC39583.1 - 0.0052 16.9 0.9 0.0098 16.0 0.2 1.9 2 0 0 2 2 2 1 Hsp20/alpha crystallin family GBP PF02263.19 EGC39584.1 - 7.2e-07 28.7 3.1 0.00011 21.6 0.1 2.4 1 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGC39584.1 - 0.00023 21.2 0.1 0.0007 19.7 0.1 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase HSP20 PF00011.21 EGC39584.1 - 0.0092 16.1 0.2 0.034 14.3 0.2 2.0 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GBP PF02263.19 EGC39585.1 - 3.3e-07 29.9 0.8 3.9e-05 23.0 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.23 EGC39585.1 - 0.00035 20.6 0.1 0.0009 19.3 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Diphthamide_syn PF01866.17 EGC39585.1 - 0.022 14.2 0.7 0.038 13.4 0.7 1.3 1 0 0 1 1 1 0 Putative diphthamide synthesis protein FAM86 PF14904.6 EGC39585.1 - 0.075 13.1 0.1 0.2 11.7 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function Bact_lectin PF18483.1 EGC39586.1 - 9e-16 58.5 18.1 9e-16 58.5 18.1 1.6 1 1 1 2 2 2 1 Bacterial lectin Patatin PF01734.22 EGC39587.1 - 5.7e-24 85.4 0.0 8.7e-24 84.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.17 EGC39587.1 - 0.0066 16.1 0.2 0.014 15.1 0.2 1.5 1 0 0 1 1 1 1 Peptidase family S51 PP-binding PF00550.25 EGC39587.1 - 0.012 16.0 0.1 0.042 14.2 0.0 1.8 2 0 0 2 2 2 0 Phosphopantetheine attachment site SRPRB PF09439.10 EGC39588.1 - 6.7e-33 113.6 0.2 8.5e-33 113.3 0.2 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.21 EGC39588.1 - 1.5e-15 57.1 0.1 2.1e-15 56.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39588.1 - 1.6e-08 34.2 0.1 2.3e-08 33.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.23 EGC39588.1 - 4.2e-08 33.3 0.1 6.5e-08 32.7 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC39588.1 - 1.1e-07 31.6 0.5 1.4e-06 27.9 0.1 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain G-alpha PF00503.20 EGC39588.1 - 2.4e-06 26.9 1.5 0.00049 19.4 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.22 EGC39588.1 - 9.7e-06 25.3 0.1 1.4e-05 24.8 0.1 1.4 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39588.1 - 1.4e-05 25.3 0.0 3.1e-05 24.2 0.0 1.6 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase FeoB_N PF02421.18 EGC39588.1 - 8.9e-05 22.1 0.6 0.00015 21.3 0.6 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B TAF4 PF05236.14 EGC39589.1 - 1.5e-34 120.0 8.9 1.5e-34 120.0 8.9 5.0 4 1 0 4 4 4 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.7 EGC39589.1 - 0.00028 20.7 14.3 0.00028 20.7 14.3 5.7 2 2 1 3 3 3 1 Transcriptional regulator of RNA polII, SAGA, subunit RhoGAP PF00620.27 EGC39590.1 - 4.6e-08 33.0 1.2 6.4e-08 32.6 1.2 1.1 1 0 0 1 1 1 1 RhoGAP domain DRAT PF07357.11 EGC39590.1 - 0.00072 18.8 0.2 0.0013 18.0 0.2 1.4 1 0 0 1 1 1 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) MASE3 PF17159.4 EGC39591.1 - 0.078 12.6 1.7 0.12 12.0 1.7 1.2 1 0 0 1 1 1 0 Membrane-associated sensor domain Ribosomal_L37e PF01907.19 EGC39592.1 - 1.8e-27 95.2 10.0 3e-27 94.5 10.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L37e DZR PF12773.7 EGC39592.1 - 0.0083 16.1 1.8 0.013 15.6 1.8 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.18 EGC39592.1 - 0.011 15.8 0.6 0.012 15.6 0.6 1.2 1 0 0 1 1 1 0 SelR domain HypA PF01155.19 EGC39592.1 - 0.077 13.0 0.6 0.11 12.5 0.6 1.3 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA DUF1462 PF07315.11 EGC39592.1 - 0.17 12.2 0.0 0.2 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zf-ribbon_3 PF13248.6 EGC39592.1 - 0.52 9.8 3.9 1.8 8.1 3.9 1.8 1 1 0 1 1 1 0 zinc-ribbon domain zn-ribbon_14 PF16503.5 EGC39592.1 - 0.71 9.4 4.9 1.8 8.2 0.4 2.2 2 0 0 2 2 2 0 Zinc-ribbon Aconitase PF00330.20 EGC39593.1 - 2.9e-178 593.6 0.0 3.8e-178 593.2 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.19 EGC39593.1 - 6.8e-40 136.4 0.0 1.3e-39 135.6 0.0 1.5 1 0 0 1 1 1 1 Aconitase C-terminal domain TFIIE_beta PF02186.15 EGC39593.1 - 0.11 12.8 0.0 0.38 11.1 0.0 1.9 1 0 0 1 1 1 0 TFIIE beta subunit core domain FNIP PF05725.12 EGC39594.1 - 8.6e-118 384.3 121.1 8.1e-13 48.3 2.9 15.5 6 3 13 20 20 20 20 FNIP Repeat DUF1769 PF08588.10 EGC39594.1 - 0.0026 17.9 11.3 16 5.8 0.0 6.9 6 1 1 7 7 7 3 Protein of unknown function (DUF1769) Dynamin_N PF00350.23 EGC39597.1 - 4.2e-05 23.7 0.7 0.00018 21.6 0.1 2.5 2 1 0 2 2 2 1 Dynamin family NIT PF08376.10 EGC39597.1 - 0.043 14.3 0.0 0.082 13.4 0.0 1.4 1 0 0 1 1 1 0 Nitrate and nitrite sensing Spore_II_R PF09551.10 EGC39597.1 - 6.6 7.2 7.4 0.85 10.1 0.2 3.2 4 0 0 4 4 4 0 Stage II sporulation protein R (spore_II_R) SapB_2 PF03489.17 EGC39598.1 - 0.12 12.5 0.0 0.4 10.8 0.0 1.9 1 0 0 1 1 1 0 Saposin-like type B, region 2 Senescence PF06911.12 EGC39599.1 - 3.8e-31 108.8 0.7 3.8e-31 108.8 0.7 2.2 3 0 0 3 3 3 1 Senescence-associated protein NYD-SP12_N PF15015.6 EGC39599.1 - 0.039 12.3 1.8 0.066 11.6 1.8 1.3 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal DUF3439 PF11921.8 EGC39599.1 - 0.64 10.0 8.6 1.3 9.0 8.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_12 PF13424.6 EGC39600.1 - 6.2e-76 250.7 23.1 2.6e-17 62.9 1.1 8.5 4 3 5 9 9 9 8 Tetratricopeptide repeat TPR_10 PF13374.6 EGC39600.1 - 8.2e-40 133.6 1.8 2.6e-07 30.3 0.0 9.0 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39600.1 - 4.3e-39 130.8 40.7 9.1e-09 34.8 0.4 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39600.1 - 1.3e-34 115.5 25.5 6.3e-06 25.9 0.1 11.6 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.6 EGC39600.1 - 4.5e-31 104.6 13.6 0.00018 21.3 0.1 10.4 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39600.1 - 8.5e-27 91.1 50.8 3.1e-05 23.8 0.5 12.0 11 0 0 11 11 11 7 Tetratricopeptide repeat DUF4062 PF13271.6 EGC39600.1 - 2.6e-16 59.7 0.5 1.5e-15 57.3 0.1 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) TPR_MalT PF17874.1 EGC39600.1 - 9.4e-13 48.2 0.0 3.5e-06 26.6 0.0 3.6 2 1 2 4 4 4 3 MalT-like TPR region BRCT_2 PF16589.5 EGC39600.1 - 1.1e-11 44.9 2.5 2.2e-11 44.0 0.1 2.9 4 0 0 4 4 1 1 BRCT domain, a BRCA1 C-terminus domain TPR_17 PF13431.6 EGC39600.1 - 8.6e-09 35.2 12.7 0.043 14.2 0.0 8.2 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC39600.1 - 5.9e-08 33.2 0.0 3 8.6 0.1 6.1 5 2 0 5 5 5 1 Tetratricopeptide repeat TPR_6 PF13174.6 EGC39600.1 - 3.9e-07 30.3 12.5 1.1 10.0 0.0 8.3 9 0 0 9 9 8 2 Tetratricopeptide repeat BRCT PF00533.26 EGC39600.1 - 7.8e-07 29.4 0.1 7.8e-07 29.4 0.1 3.1 3 0 0 3 3 2 1 BRCA1 C Terminus (BRCT) domain NACHT PF05729.12 EGC39600.1 - 2.3e-06 27.6 0.0 1.1e-05 25.4 0.0 2.2 3 0 0 3 3 3 1 NACHT domain TPR_11 PF13414.6 EGC39600.1 - 1.8e-05 24.3 28.9 0.0026 17.4 0.5 7.5 7 1 1 8 8 7 3 TPR repeat TPR_14 PF13428.6 EGC39600.1 - 2.4e-05 24.8 0.0 46 5.2 0.0 7.0 9 0 0 9 9 7 0 Tetratricopeptide repeat TPR_19 PF14559.6 EGC39600.1 - 0.00052 20.5 8.3 41 4.8 0.1 5.8 4 2 2 6 6 5 0 Tetratricopeptide repeat Mob_Pre PF01076.19 EGC39600.1 - 0.014 15.2 0.7 0.014 15.2 0.7 6.5 6 1 0 7 7 6 0 Plasmid recombination enzyme SHNi-TPR PF10516.9 EGC39600.1 - 0.031 13.7 9.1 1.9 8.0 0.0 5.2 6 0 0 6 6 6 0 SHNi-TPR DUF3856 PF12968.7 EGC39600.1 - 0.27 11.3 1.8 9.1 6.3 0.0 3.9 2 1 1 4 4 4 0 Domain of Unknown Function (DUF3856) DUF4810 PF16068.5 EGC39600.1 - 0.34 11.5 5.7 18 6.0 0.0 5.2 4 1 1 5 5 4 0 Domain of unknown function (DUF4810) MIT PF04212.18 EGC39600.1 - 0.61 10.2 38.5 0.59 10.2 1.1 8.7 10 0 0 10 10 9 0 MIT (microtubule interacting and transport) domain ABC_membrane PF00664.23 EGC39601.1 - 4.9e-37 128.1 11.7 6.2e-37 127.7 11.7 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGC39601.1 - 1.2e-34 119.7 0.0 2.4e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.19 EGC39601.1 - 3.7e-09 36.3 1.5 3.6e-07 29.8 1.5 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.6 EGC39601.1 - 3.6e-05 23.6 0.0 0.00045 20.0 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.6 EGC39601.1 - 0.00053 19.7 0.1 0.0047 16.6 0.1 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF815 PF05673.13 EGC39601.1 - 0.00055 19.2 0.0 0.0011 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) RsgA_GTPase PF03193.16 EGC39601.1 - 0.00065 19.6 0.2 0.002 18.1 0.1 1.9 2 0 0 2 2 1 1 RsgA GTPase G-alpha PF00503.20 EGC39601.1 - 0.00097 18.4 0.9 0.01 15.0 0.0 2.4 2 1 0 3 3 3 1 G-protein alpha subunit AAA_21 PF13304.6 EGC39601.1 - 0.0016 18.4 1.5 0.0086 15.9 0.1 2.4 2 1 1 3 3 3 1 AAA domain, putative AbiEii toxin, Type IV TA system Zeta_toxin PF06414.12 EGC39601.1 - 0.011 15.0 0.0 0.023 14.0 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.6 EGC39601.1 - 0.02 14.6 0.0 0.034 13.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain IstB_IS21 PF01695.17 EGC39601.1 - 0.037 13.7 0.5 26 4.5 0.0 3.9 4 0 0 4 4 4 0 IstB-like ATP binding protein AAA_16 PF13191.6 EGC39601.1 - 0.044 14.2 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA PF00004.29 EGC39601.1 - 0.053 14.0 0.1 0.62 10.5 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC39601.1 - 0.059 13.6 0.1 0.16 12.2 0.1 1.9 1 1 0 1 1 1 0 AAA domain DUF87 PF01935.17 EGC39601.1 - 0.077 13.1 0.1 0.26 11.3 0.1 1.9 1 0 0 1 1 1 0 Helicase HerA, central domain MMR_HSR1 PF01926.23 EGC39601.1 - 0.13 12.3 0.0 0.39 10.8 0.0 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.6 EGC39601.1 - 0.14 12.7 0.0 0.35 11.4 0.0 1.9 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.6 EGC39601.1 - 0.17 11.6 0.1 0.37 10.5 0.1 1.7 1 1 0 1 1 1 0 AAA domain adh_short_C2 PF13561.6 EGC39602.1 - 3.2e-43 148.0 0.0 3.9e-43 147.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGC39602.1 - 6.1e-43 146.6 0.0 7.7e-43 146.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.10 EGC39602.1 - 4.1e-08 33.4 0.1 6.2e-08 32.8 0.1 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.21 EGC39602.1 - 0.00063 19.3 0.1 0.0028 17.2 0.1 1.8 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC39602.1 - 0.0025 16.8 0.4 0.0039 16.3 0.4 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UQ_con PF00179.26 EGC39603.1 - 9.6e-15 54.5 0.0 1.1e-14 54.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.22 EGC39603.1 - 0.0061 16.8 0.0 0.0067 16.7 0.0 1.2 1 0 0 1 1 1 1 RWD domain UEV PF05743.13 EGC39603.1 - 0.079 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 UEV domain Plasmid_parti PF01672.16 EGC39604.1 - 0.13 12.9 1.5 0.64 10.7 1.5 2.2 1 0 0 1 1 1 0 Putative plasmid partition protein BCIP PF13862.6 EGC39605.1 - 1e-45 156.1 10.6 1e-45 156.1 10.6 2.7 2 2 0 2 2 2 1 p21-C-terminal region-binding protein AIF_C PF14721.6 EGC39605.1 - 0.0033 17.8 3.3 0.0033 17.8 3.3 3.7 2 1 0 2 2 2 1 Apoptosis-inducing factor, mitochondrion-associated, C-term zf-CCHC PF00098.23 EGC39607.1 - 7.3e-08 32.1 2.2 1.6e-07 31.1 2.2 1.6 1 0 0 1 1 1 1 Zinc knuckle QWRF PF04484.12 EGC39607.1 - 0.84 9.3 3.9 1.5 8.5 3.9 1.3 1 0 0 1 1 1 0 QWRF family Menin PF05053.13 EGC39607.1 - 2.6 6.3 3.8 3.6 5.8 3.8 1.2 1 0 0 1 1 1 0 Menin Reticulon PF02453.17 EGC39608.1 - 0.0042 17.1 3.7 0.27 11.2 2.5 2.2 2 0 0 2 2 2 2 Reticulon Chordopox_L2 PF05803.12 EGC39608.1 - 0.059 13.2 0.2 0.23 11.3 0.2 2.0 1 0 0 1 1 1 0 Chordopoxvirus L2 protein DUF2407 PF10302.9 EGC39608.1 - 0.12 12.9 1.1 0.27 11.8 0.0 2.0 2 0 0 2 2 2 0 DUF2407 ubiquitin-like domain DUF4834 PF16118.5 EGC39608.1 - 0.98 10.4 5.8 0.32 12.0 2.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) Methyltransf_31 PF13847.6 EGC39609.1 - 1e-19 70.8 0.2 1.3e-19 70.5 0.2 1.1 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGC39609.1 - 7.3e-10 38.6 2.1 7.7e-09 35.2 2.0 2.0 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.12 EGC39609.1 - 1.4e-09 38.6 0.1 2.1e-09 38.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC39609.1 - 1.5e-09 38.4 0.0 2.2e-09 37.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC39609.1 - 2.1e-09 37.9 0.0 3.2e-09 37.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC39609.1 - 5.4e-08 32.6 0.0 7.2e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.6 EGC39609.1 - 1.2e-07 31.7 0.0 1.8e-07 31.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.13 EGC39609.1 - 1.3e-05 24.8 0.0 1.6e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.20 EGC39609.1 - 0.00016 21.1 0.1 0.0002 20.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase TPMT PF05724.11 EGC39609.1 - 0.0015 18.2 0.0 0.0033 17.1 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.17 EGC39609.1 - 0.0055 15.9 0.0 0.017 14.3 0.0 1.6 1 1 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.17 EGC39609.1 - 0.039 13.4 0.0 0.06 12.8 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.13 EGC39609.1 - 0.044 14.1 0.0 0.084 13.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase Hemocyanin_M PF00372.19 EGC39609.1 - 0.06 12.5 1.1 0.081 12.1 0.5 1.4 1 1 0 1 1 1 0 Hemocyanin, copper containing domain NodS PF05401.11 EGC39609.1 - 0.064 12.9 0.0 0.079 12.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein S (NodS) MetW PF07021.12 EGC39609.1 - 0.07 12.7 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW bZIP_1 PF00170.21 EGC39610.1 - 2.6e-10 40.3 10.5 2.6e-10 40.3 10.5 2.6 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.15 EGC39610.1 - 0.0014 18.7 15.0 0.0014 18.7 15.0 3.8 2 1 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.17 EGC39610.1 - 0.0088 16.5 8.3 0.0088 16.5 8.3 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor TSC22 PF01166.18 EGC39610.1 - 2 8.8 6.8 1.5 9.2 2.0 2.9 2 0 0 2 2 2 0 TSC-22/dip/bun family DUF4337 PF14235.6 EGC39610.1 - 2.3 8.3 20.6 3.1 7.9 2.1 3.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4337) DOMON PF03351.17 EGC39611.1 - 1.1e-18 67.6 1.8 1.7e-18 67.0 1.8 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 EGC39611.1 - 2.4e-14 53.7 12.5 2.4e-14 53.7 12.5 1.7 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 PepSY_TM PF03929.16 EGC39611.1 - 9.1 5.9 8.0 18 4.9 8.1 1.7 1 1 0 1 1 1 0 PepSY-associated TM region Rer1 PF03248.13 EGC39612.1 - 1.9e-67 226.3 7.0 2.2e-67 226.1 7.0 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.16 EGC39612.1 - 0.31 9.9 7.9 0.48 9.3 7.9 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2208 PF09973.9 EGC39612.1 - 2 8.0 10.3 0.043 13.4 3.4 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RYDR_ITPR PF01365.21 EGC39613.1 - 7.2e-23 81.1 13.7 4.8e-14 52.3 0.2 7.4 6 1 0 6 6 6 2 RIH domain RIH_assoc PF08454.11 EGC39613.1 - 3.6e-17 62.1 4.2 3.6e-17 62.1 4.2 10.0 11 3 1 12 12 12 1 RyR and IP3R Homology associated RNase_HII PF01351.18 EGC39614.1 - 1.1e-49 169.0 0.0 1.6e-49 168.4 0.0 1.3 1 0 0 1 1 1 1 Ribonuclease HII AI-2E_transport PF01594.16 EGC39615.1 - 0.051 12.7 0.1 0.073 12.2 0.1 1.2 1 0 0 1 1 1 0 AI-2E family transporter ATP-synt_8 PF00895.20 EGC39615.1 - 3.9 8.0 5.7 19 5.8 5.7 2.2 1 1 0 1 1 1 0 ATP synthase protein 8 FNIP PF05725.12 EGC39616.1 - 9.5e-66 217.7 24.6 8.2e-17 61.1 0.5 7.3 6 1 1 7 7 7 7 FNIP Repeat LRR_5 PF13306.6 EGC39616.1 - 0.00053 19.9 0.5 0.13 12.2 0.3 3.2 1 1 2 3 3 3 2 BspA type Leucine rich repeat region (6 copies) DUF1769 PF08588.10 EGC39616.1 - 0.091 13.0 1.5 21 5.4 0.0 4.1 5 0 0 5 5 5 0 Protein of unknown function (DUF1769) WD40 PF00400.32 EGC39617.1 - 2.8e-32 110.2 29.9 1.1e-07 32.4 0.0 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.12 EGC39617.1 - 6.5e-20 71.4 0.1 1.3e-19 70.4 0.1 1.6 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.8 EGC39617.1 - 3.3e-09 35.9 15.9 1.8e-05 23.6 0.7 4.7 1 1 4 5 5 5 5 Nucleoporin Nup120/160 ANAPC4_WD40 PF12894.7 EGC39617.1 - 4.5e-05 23.7 7.2 0.053 13.8 0.2 4.7 2 1 3 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain Cob_adeno_trans PF01923.18 EGC39618.1 - 5.8e-53 179.4 0.2 8.4e-53 178.9 0.0 1.3 2 0 0 2 2 2 1 Cobalamin adenosyltransferase Ebp2 PF05890.12 EGC39621.1 - 3e-81 272.9 34.1 3e-81 272.9 34.1 3.2 2 1 0 2 2 2 1 Eukaryotic rRNA processing protein EBP2 CTP_transf_like PF01467.26 EGC39621.1 - 0.93 9.7 6.1 0.5 10.6 2.5 2.4 2 0 0 2 2 2 0 Cytidylyltransferase-like DUF1084 PF06454.11 EGC39622.1 - 1.4e-10 41.0 26.4 2.5e-10 40.2 26.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) TFIIA PF03153.13 EGC39624.1 - 0.25 11.3 30.5 0.32 11.0 30.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF4175 PF13779.6 EGC39624.1 - 7.4 4.3 16.9 11 3.8 16.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pkinase_Tyr PF07714.17 EGC39625.1 - 4.4e-64 216.3 0.0 7.7e-64 215.5 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC39625.1 - 1.8e-47 161.9 0.0 1.8e-47 161.9 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain LRR_8 PF13855.6 EGC39625.1 - 9.1e-40 134.2 75.7 7.4e-14 51.3 3.2 7.5 4 1 4 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EGC39625.1 - 1.7e-22 79.1 78.3 1.1e-06 28.9 4.6 9.8 5 1 5 11 11 11 8 Leucine Rich repeats (2 copies) LRR_9 PF14580.6 EGC39625.1 - 1.2e-07 31.4 32.2 0.0015 18.0 4.5 4.9 1 1 2 4 4 4 4 Leucine-rich repeat CPBP PF02517.16 EGC39626.1 - 1.4e-14 54.2 15.5 4.8e-13 49.3 15.5 2.4 1 1 0 1 1 1 1 CPBP intramembrane metalloprotease Yip1 PF04893.17 EGC39626.1 - 0.011 15.5 5.3 0.011 15.5 5.3 2.8 2 1 0 2 2 2 0 Yip1 domain DUF4131 PF13567.6 EGC39626.1 - 1.7 8.3 5.5 3.9 7.1 0.1 2.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) PalH PF08733.10 EGC39626.1 - 5 6.0 13.8 0.19 10.7 4.9 2.1 2 0 0 2 2 2 0 PalH/RIM21 Trp_dioxygenase PF03301.13 EGC39627.1 - 0.00064 19.2 4.1 0.00093 18.6 4.1 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Presenilin PF01080.17 EGC39627.1 - 0.002 17.0 11.4 0.0023 16.8 11.4 1.2 1 0 0 1 1 1 1 Presenilin CDC45 PF02724.14 EGC39627.1 - 0.054 11.8 14.6 0.068 11.5 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.22 EGC39627.1 - 0.12 11.6 11.7 0.16 11.2 11.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter PA26 PF04636.13 EGC39627.1 - 0.15 11.0 10.9 0.2 10.6 10.9 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Band_3_cyto PF07565.13 EGC39627.1 - 0.36 10.6 9.7 0.54 10.0 9.7 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain SLC12 PF03522.15 EGC39627.1 - 0.6 9.1 17.7 0.8 8.7 17.7 1.2 1 0 0 1 1 1 0 Solute carrier family 12 PBP_sp32 PF07222.12 EGC39627.1 - 1.5 8.2 18.5 2.3 7.6 18.5 1.3 1 0 0 1 1 1 0 Proacrosin binding protein sp32 Endostatin PF06482.11 EGC39627.1 - 1.7 8.0 10.6 2.2 7.7 10.6 1.2 1 0 0 1 1 1 0 Collagenase NC10 and Endostatin DUF966 PF06136.13 EGC39627.1 - 3 7.5 21.1 3.7 7.2 21.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Neur_chan_memb PF02932.16 EGC39627.1 - 3.2 7.8 8.3 4.6 7.2 8.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RR_TM4-6 PF06459.12 EGC39627.1 - 3.5 7.4 25.5 5.1 6.8 25.5 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Asp-B-Hydro_N PF05279.11 EGC39627.1 - 6.4 6.8 28.5 8.7 6.3 28.5 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region OATP PF03137.20 EGC39627.1 - 9.2 4.4 8.7 17 3.5 8.7 1.5 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family EamA PF00892.20 EGC39628.1 - 8.6e-37 126.4 39.9 6.5e-19 68.5 13.4 2.4 2 0 0 2 2 2 2 EamA-like transporter family DUF1129 PF06570.11 EGC39628.1 - 0.001 18.6 1.5 0.001 18.6 1.5 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1129) TMEM234 PF10639.9 EGC39628.1 - 0.009 16.0 2.6 0.66 10.0 0.5 2.9 2 0 0 2 2 2 2 Putative transmembrane family 234 Ldh_1_C PF02866.18 EGC39629.1 - 6e-36 123.9 0.0 9.4e-36 123.3 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.23 EGC39629.1 - 8.1e-30 103.8 0.0 1.2e-29 103.2 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF3439 PF11921.8 EGC39630.1 - 0.00087 19.2 5.0 0.00087 19.2 5.0 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF3439) zf-RING_2 PF13639.6 EGC39630.1 - 0.0039 17.5 8.0 0.0095 16.2 8.0 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC39630.1 - 0.76 9.7 8.1 2 8.3 8.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC39630.1 - 3.9 7.4 9.4 3.3 7.7 4.6 2.6 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 Cnd1 PF12717.7 EGC39631.1 - 3.2e-29 102.1 28.5 2.9e-23 82.7 0.2 7.0 7 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.22 EGC39631.1 - 6.6e-12 44.6 12.4 0.1 12.9 0.0 7.2 7 0 0 7 7 7 4 HEAT repeat Adaptin_N PF01602.20 EGC39631.1 - 2.2e-11 43.0 15.2 0.0002 20.1 6.6 3.7 3 0 0 3 3 3 3 Adaptin N terminal region CLASP_N PF12348.8 EGC39631.1 - 1.6e-06 27.9 8.3 0.006 16.2 0.2 4.3 3 1 1 4 4 4 2 CLASP N terminal Cohesin_HEAT PF12765.7 EGC39631.1 - 5.7e-06 26.5 2.4 0.078 13.3 0.1 4.7 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.6 EGC39631.1 - 9.9e-06 25.9 0.2 0.001 19.4 0.0 3.5 3 0 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.6 EGC39631.1 - 1.7e-05 25.2 1.8 0.24 11.9 0.0 4.8 4 1 1 5 5 5 1 HEAT-like repeat UNC45-central PF11701.8 EGC39631.1 - 0.34 10.8 11.1 0.77 9.7 0.2 5.6 4 2 0 5 5 5 0 Myosin-binding striated muscle assembly central AMP-binding PF00501.28 EGC39632.1 - 1.4e-78 264.4 0.0 1.8e-78 264.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC39632.1 - 2.2e-19 70.2 0.0 4.3e-19 69.3 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sod_Cu PF00080.20 EGC39633.1 - 7.9e-47 159.0 8.1 9.3e-47 158.8 8.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Vps54_N PF10475.9 EGC39635.1 - 5e-105 350.9 7.3 5e-105 350.9 7.3 1.9 2 0 0 2 2 2 1 Vacuolar-sorting protein 54, of GARP complex DUF2451 PF10474.9 EGC39635.1 - 9.6e-61 205.5 3.2 1.4e-60 205.0 0.2 2.7 2 1 0 2 2 2 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.11 EGC39635.1 - 0.025 14.7 2.0 0.1 12.7 0.8 2.8 2 1 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 Vps54 PF07928.12 EGC39635.1 - 0.14 12.6 10.0 0.31 11.5 0.2 4.6 3 1 1 4 4 4 0 Vps54-like protein DUF2407_C PF13373.6 EGC39635.1 - 0.18 12.0 1.0 0.36 11.0 1.0 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain RP-C_C PF11800.8 EGC39635.1 - 0.28 11.3 5.9 2 8.5 4.0 2.4 2 0 0 2 2 2 0 Replication protein C C-terminal region Zip PF02535.22 EGC39635.1 - 0.64 9.2 7.9 1.1 8.5 7.9 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter PBP1_TM PF14812.6 EGC39635.1 - 1.5 9.3 5.6 3.2 8.2 5.6 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal EIIBC-GUT_N PF03612.14 EGC39635.1 - 3.1 7.5 5.5 6.3 6.5 5.5 1.5 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Roughex PF06020.11 EGC39635.1 - 3.6 6.6 13.3 0.67 9.0 8.6 1.9 2 0 0 2 2 2 0 Drosophila roughex protein Suf PF05843.14 EGC39635.1 - 9.5 6.1 15.5 1.3 9.0 9.5 2.2 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) Ribosomal_S10 PF00338.22 EGC39636.1 - 1.4e-25 89.4 0.3 1.9e-25 89.0 0.3 1.2 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2418 PF10332.9 EGC39637.1 - 3.4e-19 69.2 1.4 3.4e-19 69.2 1.4 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) PAP2_3 PF14378.6 EGC39637.1 - 4.9 6.8 7.5 22 4.7 7.5 1.9 1 1 0 1 1 1 0 PAP2 superfamily AAA PF00004.29 EGC39638.1 - 1.2e-89 297.6 0.4 1e-44 152.2 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC39638.1 - 9.9e-25 86.1 0.1 1.1e-13 50.7 0.1 2.6 2 0 0 2 2 2 2 AAA+ lid domain RuvB_N PF05496.12 EGC39638.1 - 5.6e-15 55.4 0.0 2.7e-06 27.2 0.0 3.3 2 1 1 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGC39638.1 - 8.4e-12 45.3 0.3 6.6e-06 26.2 0.1 4.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.14 EGC39638.1 - 7.6e-10 39.2 0.1 0.00026 21.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.6 EGC39638.1 - 2e-08 34.8 0.4 0.016 15.6 0.0 3.7 2 2 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.6 EGC39638.1 - 1.2e-07 32.1 0.4 0.013 15.7 0.0 4.3 2 2 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGC39638.1 - 6.4e-06 26.5 1.2 0.38 11.2 0.0 4.0 4 0 0 4 4 3 2 RNA helicase AAA_14 PF13173.6 EGC39638.1 - 7e-06 26.1 5.7 0.025 14.6 0.0 4.3 4 0 0 4 4 4 2 AAA domain AAA_33 PF13671.6 EGC39638.1 - 1.8e-05 24.9 0.0 0.29 11.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EGC39638.1 - 1.9e-05 24.6 0.1 0.058 13.4 0.0 2.8 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain CDC48_N PF02359.18 EGC39638.1 - 1.9e-05 24.8 0.0 0.00034 20.7 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_25 PF13481.6 EGC39638.1 - 2.3e-05 24.1 0.5 1.9 8.0 0.1 3.7 3 1 0 3 3 3 2 AAA domain Mg_chelatase PF01078.21 EGC39638.1 - 3.6e-05 23.3 2.8 0.093 12.1 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.17 EGC39638.1 - 6.1e-05 22.8 0.0 0.42 10.3 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_24 PF13479.6 EGC39638.1 - 0.0002 21.1 0.0 0.028 14.1 0.0 2.6 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.13 EGC39638.1 - 0.00023 20.5 8.0 0.11 11.6 0.0 3.9 4 1 0 4 4 3 2 TIP49 P-loop domain AAA_7 PF12775.7 EGC39638.1 - 0.00034 20.2 0.1 0.47 9.9 0.0 3.3 3 0 0 3 3 3 1 P-loop containing dynein motor region ATPase PF06745.13 EGC39638.1 - 0.00062 19.2 0.2 0.64 9.3 0.0 2.8 2 0 0 2 2 2 2 KaiC AAA_28 PF13521.6 EGC39638.1 - 0.0011 19.2 0.0 2.1 8.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.26 EGC39638.1 - 0.0014 18.3 0.0 0.23 11.1 0.0 3.1 2 1 0 2 2 2 1 Sigma-54 interaction domain Sigma54_activ_2 PF14532.6 EGC39638.1 - 0.0021 18.2 0.0 4.6 7.4 0.0 3.1 2 0 0 2 2 2 2 Sigma-54 interaction domain TsaE PF02367.17 EGC39638.1 - 0.0026 17.7 0.1 3.2 7.8 0.0 2.8 2 1 0 2 2 2 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_3 PF07726.11 EGC39638.1 - 0.0029 17.5 0.0 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.12 EGC39638.1 - 0.012 14.9 0.1 3 7.1 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin AAA_18 PF13238.6 EGC39638.1 - 0.013 16.1 0.0 0.013 16.1 0.0 4.7 5 1 0 5 5 4 0 AAA domain NACHT PF05729.12 EGC39638.1 - 0.059 13.3 0.4 8.9 6.2 0.0 3.1 3 1 0 3 3 3 0 NACHT domain ABC_tran PF00005.27 EGC39638.1 - 0.14 12.7 0.0 0.14 12.7 0.0 3.8 2 1 1 3 3 2 0 ABC transporter AAA_11 PF13086.6 EGC39638.1 - 0.84 9.4 8.1 2.1 8.1 0.1 3.4 2 1 1 3 3 3 0 AAA domain ArgoMid PF16487.5 EGC39638.1 - 5.7 7.3 6.2 2.9 8.2 3.0 2.2 2 0 0 2 2 1 0 Mid domain of argonaute ubiquitin PF00240.23 EGC39639.1 - 2.1e-26 91.5 0.2 2.4e-26 91.3 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC39639.1 - 1.3e-11 44.2 0.1 1.5e-11 44.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC39639.1 - 0.00092 19.6 0.1 0.00092 19.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC39639.1 - 0.0027 17.6 0.0 0.0028 17.6 0.0 1.2 1 0 0 1 1 1 1 TANK binding kinase 1 ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC39639.1 - 0.0056 16.8 0.0 0.011 15.8 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC39639.1 - 0.037 14.6 0.0 0.041 14.4 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Phosphodiest PF01663.22 EGC39640.1 - 1.3e-11 44.7 0.3 4.4e-11 43.0 0.1 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase TIG PF01833.24 EGC39640.1 - 9.7e-08 32.0 43.9 0.00018 21.5 1.1 6.7 5 2 2 7 7 7 4 IPT/TIG domain Metalloenzyme PF01676.18 EGC39640.1 - 7e-07 28.9 0.2 1.4e-06 27.9 0.2 1.5 1 0 0 1 1 1 1 Metalloenzyme superfamily DUF3925 PF13063.6 EGC39640.1 - 0.19 11.9 3.2 25 5.2 0.8 4.2 4 0 0 4 4 4 0 Protein of unknown function (DUF3925) ETRAMP PF09716.10 EGC39640.1 - 4.6 7.4 7.2 4.7 7.3 0.5 4.1 2 1 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) Arf PF00025.21 EGC39641.1 - 2.2e-41 141.2 0.0 7.1e-41 139.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Roc PF08477.13 EGC39641.1 - 2.1e-05 24.7 0.1 5.4e-05 23.4 0.1 1.8 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase NACHT PF05729.12 EGC39641.1 - 0.0012 18.8 0.3 0.027 14.4 0.3 2.3 1 1 0 1 1 1 1 NACHT domain AAA_24 PF13479.6 EGC39641.1 - 0.012 15.3 0.1 0.028 14.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain Ras PF00071.22 EGC39641.1 - 0.037 13.6 0.1 0.037 13.6 0.1 2.1 2 0 0 2 2 2 0 Ras family AAA PF00004.29 EGC39641.1 - 0.051 14.0 0.0 0.13 12.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.6 EGC39641.1 - 0.063 13.6 0.1 1.2 9.4 0.0 2.4 2 0 0 2 2 2 0 AAA domain SRPRB PF09439.10 EGC39641.1 - 0.097 12.1 0.1 0.097 12.1 0.1 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit SRP54 PF00448.22 EGC39641.1 - 0.12 12.0 0.1 0.22 11.1 0.1 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain PAP_assoc PF03828.19 EGC39642.1 - 5.2e-19 68.2 0.2 1.9e-18 66.4 0.2 1.9 2 0 0 2 2 2 1 Cid1 family poly A polymerase RasGEF PF00617.19 EGC39642.1 - 0.055 13.7 0.3 0.11 12.7 0.3 1.5 1 0 0 1 1 1 0 RasGEF domain RCC1 PF00415.18 EGC39643.1 - 4.9e-35 119.9 0.0 1.2e-11 45.1 0.0 6.6 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC39643.1 - 1.3e-24 85.4 1.1 9.2e-10 38.1 0.1 5.9 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Dirigent PF03018.14 EGC39644.1 - 0.017 14.9 0.0 0.024 14.4 0.0 1.3 1 0 0 1 1 1 0 Dirigent-like protein DUF2953 PF11167.8 EGC39645.1 - 0.12 12.5 0.0 0.17 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) RCC1 PF00415.18 EGC39646.1 - 9.1e-77 253.5 11.2 9.3e-14 51.8 0.2 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.6 EGC39646.1 - 2.7e-34 116.3 33.8 8e-10 38.3 1.6 7.5 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.6 EGC39646.1 - 0.019 15.2 0.3 3.6 7.9 0.0 2.7 1 1 1 2 2 2 0 Putative heavy-metal chelation DUF4998 PF16389.5 EGC39646.1 - 0.081 12.5 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function p450 PF00067.22 EGC39648.1 - 8e-98 328.2 0.0 9.1e-98 328.0 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pox_A28 PF04584.14 EGC39650.1 - 0.46 10.7 3.2 0.38 10.9 1.6 1.7 2 0 0 2 2 2 0 Poxvirus A28 family Amastin PF07344.11 EGC39650.1 - 0.59 10.0 12.2 0.016 15.1 3.9 2.0 1 1 0 2 2 2 0 Amastin surface glycoprotein Amastin PF07344.11 EGC39651.1 - 0.59 10.0 7.0 0.36 10.7 4.3 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein Glyco_hydro_38N PF01074.22 EGC39652.1 - 1.2e-77 261.1 6.1 1.2e-77 261.1 6.1 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC39652.1 - 3.7e-15 55.8 0.0 3e-14 52.9 0.0 2.6 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38N PF01074.22 EGC39653.1 - 6.9e-71 239.0 6.5 6.9e-71 239.0 6.5 2.1 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC39653.1 - 1.2e-18 67.1 1.9 1.9e-18 66.4 0.8 2.0 2 0 0 2 2 2 1 Alpha mannosidase middle domain Glyco_hydro_38C PF07748.13 EGC39653.1 - 6.3e-17 62.4 1.9 6.3e-17 62.4 1.9 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Ins134_P3_kin PF05770.11 EGC39653.1 - 0.017 14.6 0.7 0.18 11.3 0.1 2.4 1 1 1 2 2 2 0 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Glyco_hydro_38N PF01074.22 EGC39654.1 - 5.7e-57 193.3 0.3 9.6e-57 192.5 0.3 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.11 EGC39654.1 - 1e-15 57.6 0.1 4.3e-15 55.6 0.1 2.2 1 0 0 1 1 1 1 Alpha mannosidase middle domain Myotub-related PF06602.14 EGC39655.1 - 4.5e-140 466.6 0.0 1e-139 465.4 0.0 1.6 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.20 EGC39655.1 - 0.00012 21.9 1.7 0.00012 21.9 1.7 3.0 3 0 0 3 3 3 1 GRAM domain Y_phosphatase3 PF13350.6 EGC39655.1 - 0.032 14.2 0.1 0.097 12.6 0.0 1.8 2 0 0 2 2 2 0 Tyrosine phosphatase family 3-PAP PF12578.8 EGC39655.1 - 2.1 8.1 4.6 0.52 10.0 0.2 2.2 2 1 0 2 2 2 0 Myotubularin-associated protein Phospholip_B PF04916.13 EGC39656.1 - 4.9e-159 530.3 11.9 5.5e-159 530.2 11.9 1.0 1 0 0 1 1 1 1 Phospholipase B FNIP PF05725.12 EGC39657.1 - 1.9e-181 588.1 43.3 7.4e-14 51.6 0.0 14.6 8 2 5 16 16 16 16 FNIP Repeat K1 PF02960.14 EGC39657.1 - 0.0065 16.6 0.1 18 5.5 0.0 4.5 4 1 1 5 5 5 1 K1 glycoprotein DUF4493 PF14900.6 EGC39657.1 - 0.48 10.2 1.6 36 4.1 0.0 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF4493) Dimer_Tnp_hAT PF05699.14 EGC39658.1 - 0.0014 18.4 0.1 0.0026 17.5 0.1 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region NOG1_N PF17835.1 EGC39659.1 - 8.7e-15 55.0 0.0 2.3e-14 53.7 0.0 1.8 1 0 0 1 1 1 1 NOG1 N-terminal helical domain CutA1 PF03091.15 EGC39659.1 - 0.0057 16.5 0.0 0.015 15.2 0.0 1.7 1 0 0 1 1 1 1 CutA1 divalent ion tolerance protein tRNA_SAD PF07973.14 EGC39660.1 - 2.8e-05 24.1 0.0 6.7e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain N6-adenineMlase PF10237.9 EGC39661.1 - 8.1e-47 159.0 1.5 9.6e-47 158.8 1.5 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.15 EGC39661.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 1 0 1 1 1 0 Conserved hypothetical protein 95 DUF2701 PF10857.8 EGC39662.1 - 0.2 11.7 1.0 0.52 10.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) Metal_resist PF13801.6 EGC39664.1 - 1.5 9.0 4.7 11 6.3 0.7 2.8 3 0 0 3 3 3 0 Heavy-metal resistance PS_Dcarbxylase PF02666.15 EGC39664.1 - 4.5 6.8 8.9 4.2 6.9 0.0 3.0 3 0 0 3 3 3 0 Phosphatidylserine decarboxylase SAYSvFN PF10260.9 EGC39664.1 - 5.2 7.1 16.0 6.4 6.8 0.2 5.2 3 2 3 6 6 6 0 Uncharacterized conserved domain (SAYSvFN) Actin PF00022.19 EGC39665.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin Nanovirus_coat PF04660.12 EGC39666.1 - 0.099 12.7 0.0 0.14 12.2 0.0 1.2 1 0 0 1 1 1 0 Nanovirus coat protein XRN1_D2_D3 PF18334.1 EGC39667.1 - 0.0017 18.5 0.1 0.0046 17.1 0.1 1.7 1 0 0 1 1 1 1 Exoribonuclease Xrn1 D2/D3 domain GPHH PF16905.5 EGC39667.1 - 0.2 11.4 0.0 4 7.3 0.0 2.4 2 0 0 2 2 2 0 Voltage-dependent L-type calcium channel, IQ-associated EGF_2 PF07974.13 EGC39667.1 - 1.6 9.1 16.4 0.17 12.2 11.6 1.9 2 0 0 2 2 2 0 EGF-like domain IMUP PF15761.5 EGC39668.1 - 1.9 9.2 11.5 3.7 8.3 11.5 1.4 1 0 0 1 1 1 0 Immortalisation up-regulated protein PolyA_pol PF01743.20 EGC39669.1 - 1.3e-21 77.4 0.1 3.5e-21 75.9 0.1 1.8 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.7 EGC39669.1 - 3.2e-07 30.0 0.3 1.5e-06 27.9 0.0 2.3 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Fam20C PF06702.12 EGC39669.1 - 0.023 14.5 0.0 0.06 13.2 0.0 1.8 1 0 0 1 1 1 0 Golgi casein kinase, C-terminal, Fam20 PhosphMutase PF10143.9 EGC39669.1 - 0.14 12.0 0.0 0.43 10.4 0.0 1.8 1 0 0 1 1 1 0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase DUF4306 PF14154.6 EGC39669.1 - 0.54 10.4 3.1 4.2 7.6 0.5 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4306) Pkinase PF00069.25 EGC39670.1 - 2.3e-39 135.3 1.6 2.1e-38 132.2 1.6 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39670.1 - 4.3e-20 72.1 0.1 1.1e-19 70.8 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.12 EGC39670.1 - 3e-17 62.5 27.6 4.6e-09 36.3 0.2 5.7 4 1 1 5 5 5 3 FNIP Repeat Pkinase_fungal PF17667.1 EGC39670.1 - 9.4e-06 24.7 0.0 1.3e-05 24.2 0.0 1.1 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC39670.1 - 0.019 14.3 0.0 0.029 13.7 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC39670.1 - 0.04 13.2 0.0 0.061 12.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like BRCT PF00533.26 EGC39671.1 - 5e-20 71.7 3.0 7.4e-09 35.9 0.5 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain BRCT_2 PF16589.5 EGC39671.1 - 4.7e-17 62.2 1.7 7.3e-09 35.9 0.1 2.9 2 0 0 2 2 2 2 BRCT domain, a BRCA1 C-terminus domain RTT107_BRCT_5 PF16770.5 EGC39671.1 - 1.1e-12 47.6 1.0 3.7e-12 46.0 1.0 2.0 1 0 0 1 1 1 1 Regulator of Ty1 transposition protein 107 BRCT domain FHA PF00498.26 EGC39671.1 - 1.4e-10 41.3 0.1 4.5e-10 39.7 0.1 1.9 1 0 0 1 1 1 1 FHA domain Yop-YscD_cpl PF16697.5 EGC39671.1 - 2e-07 31.2 0.0 5.2e-07 29.9 0.0 1.7 1 0 0 1 1 1 1 Inner membrane component of T3SS, cytoplasmic domain PTCB-BRCT PF12738.7 EGC39671.1 - 3.7e-07 30.0 0.0 0.00018 21.4 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain LIG3_BRCT PF16759.5 EGC39671.1 - 0.03 14.6 0.0 0.12 12.7 0.0 2.0 1 0 0 1 1 1 0 DNA ligase 3 BRCT domain XRN_N PF03159.18 EGC39673.1 - 9.8e-43 146.3 0.8 1.2e-42 146.0 0.8 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.17 EGC39673.1 - 0.00016 22.1 0.1 0.00031 21.2 0.1 1.4 1 0 0 1 1 1 1 XPG N-terminal domain Glyco_hydro_88 PF07470.13 EGC39673.1 - 0.016 14.3 0.1 0.022 13.8 0.1 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 XRN_M PF17846.1 EGC39673.1 - 0.016 14.2 0.0 0.031 13.3 0.0 1.5 1 0 0 1 1 1 0 Xrn1 helical domain XPG_I PF00867.18 EGC39673.1 - 0.032 14.6 1.0 0.054 13.8 0.2 1.8 2 0 0 2 2 2 0 XPG I-region ketoacyl-synt PF00109.26 EGC39674.1 - 7.9e-45 153.4 0.0 1.1e-44 153.0 0.0 1.1 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.23 EGC39674.1 - 2e-05 24.1 0.1 3.9e-05 23.2 0.1 1.5 1 1 0 1 1 1 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.21 EGC39675.1 - 2.3e-40 139.1 0.0 1.9e-39 136.1 0.0 2.1 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.12 EGC39675.1 - 2e-16 60.6 0.1 1.7e-15 57.5 0.0 2.9 2 0 0 2 2 1 1 Methyltransferase domain KR PF08659.10 EGC39675.1 - 4e-16 59.4 0.0 8.2e-16 58.4 0.0 1.5 1 0 0 1 1 1 1 KR domain ADH_zinc_N_2 PF13602.6 EGC39675.1 - 2.8e-10 41.3 0.0 7.5e-10 40.0 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PS-DH PF14765.6 EGC39675.1 - 1e-07 31.5 0.0 1.5e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.12 EGC39675.1 - 2e-07 30.9 0.0 5.6e-07 29.4 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.12 EGC39675.1 - 2.3e-07 31.3 0.0 2.9e-06 27.8 0.0 2.8 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC39675.1 - 8.7e-07 28.8 0.6 1.8e-05 24.6 0.1 3.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC39675.1 - 8.1e-06 26.5 0.0 3.4e-05 24.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.26 EGC39675.1 - 2.8e-05 24.1 0.0 7.6e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.18 EGC39675.1 - 0.00011 21.6 0.0 0.00039 19.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.6 EGC39675.1 - 0.00051 19.9 0.1 0.0016 18.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.25 EGC39675.1 - 0.0046 17.3 0.1 0.012 15.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site BTB PF00651.31 EGC39676.1 - 1.3e-24 86.6 0.0 1.2e-22 80.2 0.0 2.7 1 1 1 2 2 2 1 BTB/POZ domain DUF3361 PF11841.8 EGC39676.1 - 0.012 15.5 1.6 0.79 9.7 0.2 2.8 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) BACK PF07707.15 EGC39676.1 - 0.028 14.5 0.0 0.19 11.9 0.0 2.3 2 0 0 2 2 2 0 BTB And C-terminal Kelch Arm PF00514.23 EGC39676.1 - 0.21 11.7 2.3 14 5.9 0.4 4.3 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat GTP_cyclohydroI PF01227.22 EGC39677.1 - 0.11 11.9 0.2 0.14 11.5 0.2 1.3 1 1 0 1 1 1 0 GTP cyclohydrolase I TIG PF01833.24 EGC39678.1 - 4.4e-33 113.2 69.9 4e-13 49.2 1.9 10.1 8 1 1 9 9 9 9 IPT/TIG domain EGF_2 PF07974.13 EGC39678.1 - 3.6e-05 24.0 11.6 3.6e-05 24.0 11.6 2.0 2 0 0 2 2 2 1 EGF-like domain Lectin_C PF00059.21 EGC39678.1 - 0.0022 18.7 0.7 0.013 16.2 0.7 2.5 1 0 0 1 1 1 1 Lectin C-type domain EGF PF00008.27 EGC39678.1 - 0.11 12.8 9.2 0.18 12.1 6.0 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.24 EGC39678.1 - 0.32 11.2 8.9 0.84 9.8 8.9 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_CA PF07645.15 EGC39678.1 - 0.37 11.0 8.9 1.4 9.2 8.9 2.0 1 0 0 1 1 1 0 Calcium-binding EGF domain Gram_pos_anchor PF00746.21 EGC39678.1 - 1.1 9.3 3.7 17 5.5 1.4 2.5 2 0 0 2 2 2 0 LPXTG cell wall anchor motif DSL PF01414.19 EGC39678.1 - 4.8 7.5 9.6 20 5.5 9.6 2.2 1 0 0 1 1 1 0 Delta serrate ligand Tcell_CD4_C PF12104.8 EGC39679.1 - 0.18 11.8 1.2 0.28 11.1 1.2 1.2 1 0 0 1 1 1 0 T cell CD4 receptor C terminal region Ras PF00071.22 EGC39680.1 - 4.8e-47 159.6 0.5 5.8e-47 159.3 0.5 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39680.1 - 8.3e-17 61.5 0.0 1.5e-16 60.7 0.0 1.3 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39680.1 - 2.7e-08 33.5 0.0 3.1e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC39680.1 - 1.7e-05 24.8 0.0 2.9e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.27 EGC39680.1 - 0.00024 20.7 0.2 0.00057 19.5 0.1 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain PKD_channel PF08016.12 EGC39681.1 - 2.7e-46 158.1 16.3 2.7e-46 158.1 16.3 1.5 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.31 EGC39681.1 - 1.3e-07 31.1 24.2 1.3e-07 31.1 24.2 2.1 2 0 0 2 2 2 1 Ion transport protein Baculo_11_kDa PF06143.11 EGC39681.1 - 0.022 14.3 5.4 0.97 9.0 0.2 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family FUSC PF04632.12 EGC39681.1 - 0.74 8.3 8.2 1.2 7.6 8.2 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PhyH PF05721.13 EGC39683.1 - 7.2e-12 46.0 0.0 5.5e-09 36.6 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.12 EGC39683.1 - 0.00032 19.6 0.0 0.01 14.7 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.6 EGC39683.1 - 0.0091 16.4 0.1 0.036 14.5 0.0 2.1 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase 2OG-FeII_Oxy_3 PF13640.6 EGC39683.1 - 0.013 16.3 0.0 0.033 15.1 0.0 1.7 1 1 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Fra10Ac1 PF09725.9 EGC39684.1 - 2.2e-52 176.4 1.4 2.2e-52 176.4 1.4 3.0 4 0 0 4 4 4 1 Folate-sensitive fragile site protein Fra10Ac1 COX6C PF02937.15 EGC39684.1 - 0.29 11.3 0.1 0.29 11.3 0.1 3.2 3 1 1 4 4 4 0 Cytochrome c oxidase subunit VIc Atrophin-1 PF03154.15 EGC39684.1 - 0.82 7.9 9.6 1.1 7.4 9.6 1.3 1 0 0 1 1 1 0 Atrophin-1 family Afi1 PF07792.12 EGC39684.1 - 1.6 9.2 22.9 0.23 12.0 10.9 2.3 2 0 0 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking Rtf2 PF04641.12 EGC39684.1 - 4.1 6.7 26.5 0.084 12.2 17.7 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Nucleoside_tran PF01733.18 EGC39684.1 - 4.9 6.4 4.2 13 5.0 4.2 1.8 1 1 0 1 1 1 0 Nucleoside transporter Acetyltransf_3 PF13302.7 EGC39685.1 - 1.1e-22 81.2 0.2 1.4e-22 80.9 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC39685.1 - 7.9e-08 32.5 0.0 1.1e-07 32.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.6 EGC39685.1 - 1.3e-06 28.2 0.4 1.2e-05 25.0 0.4 2.0 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC39685.1 - 2e-06 28.0 3.3 4.2e-06 27.0 3.3 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.10 EGC39685.1 - 4.7e-06 26.5 0.1 7.7e-06 25.8 0.1 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.7 EGC39685.1 - 0.00079 19.4 0.1 0.0016 18.4 0.1 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain ATG2_CAD PF13329.6 EGC39685.1 - 0.13 12.0 0.0 0.18 11.5 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif CX9C PF16860.5 EGC39686.1 - 0.0064 16.5 6.0 0.012 15.6 0.4 2.7 2 1 0 2 2 2 2 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, RhoGAP PF00620.27 EGC39687.1 - 6.6e-39 133.2 0.3 1.5e-38 132.0 0.3 1.7 1 0 0 1 1 1 1 RhoGAP domain PH PF00169.29 EGC39688.1 - 6.9e-22 77.9 1.1 6.9e-22 77.9 1.1 2.2 2 1 0 2 2 2 1 PH domain PH_9 PF15410.6 EGC39688.1 - 0.0032 17.8 1.5 0.044 14.2 0.1 2.9 2 2 0 2 2 2 1 Pleckstrin homology domain PH_13 PF16652.5 EGC39688.1 - 0.0033 17.2 1.7 0.01 15.6 0.0 2.3 2 1 1 3 3 3 1 Pleckstrin homology domain PH_11 PF15413.6 EGC39688.1 - 0.004 17.5 2.1 0.004 17.5 2.1 3.1 2 2 0 2 2 2 1 Pleckstrin homology domain PH_2 PF08458.10 EGC39688.1 - 0.0041 17.5 0.3 0.01 16.2 0.0 1.8 2 0 0 2 2 2 1 Plant pleckstrin homology-like region PH_6 PF15406.6 EGC39688.1 - 0.063 13.6 0.0 0.15 12.3 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain DUF3707 PF12499.8 EGC39688.1 - 0.088 13.4 0.2 0.19 12.3 0.2 1.6 1 1 0 1 1 1 0 Pherophorin N6_N4_Mtase PF01555.18 EGC39688.1 - 0.19 11.4 4.6 0.072 12.8 2.1 1.5 2 0 0 2 2 2 0 DNA methylase BCL_N PF04714.13 EGC39688.1 - 0.29 11.2 0.3 0.29 11.2 0.3 2.1 2 0 0 2 2 2 0 BCL7, N-terminal conserver region Mst1_SARAH PF11629.8 EGC39688.1 - 0.58 10.3 10.3 3.4 7.8 2.3 2.6 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 FNIP PF05725.12 EGC39690.1 - 3.1e-108 353.7 78.2 2e-15 56.7 0.1 14.8 7 3 9 18 18 18 16 FNIP Repeat Pkinase PF00069.25 EGC39691.1 - 2.7e-42 145.0 0.1 4.3e-42 144.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39691.1 - 1.7e-19 70.2 0.5 1e-18 67.6 0.0 2.1 2 1 0 2 2 2 1 Protein tyrosine kinase FNIP PF05725.12 EGC39691.1 - 1.7e-19 69.7 40.5 1.2e-07 31.8 0.9 5.4 2 1 4 6 6 6 5 FNIP Repeat Kinase-like PF14531.6 EGC39691.1 - 0.00044 19.6 0.0 0.00064 19.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2779 PF11074.8 EGC39691.1 - 0.0021 18.6 0.3 0.0061 17.0 0.3 1.8 1 0 0 1 1 1 1 Domain of unknown function(DUF2779) Choline_kinase PF01633.20 EGC39691.1 - 0.0042 16.7 0.1 0.0093 15.6 0.1 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.23 EGC39691.1 - 0.0096 15.9 0.0 0.014 15.4 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.9 EGC39691.1 - 0.063 12.8 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL RNA_pol_Rpb4 PF03874.16 EGC39691.1 - 0.073 13.4 3.5 0.25 11.7 0.1 2.9 3 1 0 3 3 3 0 RNA polymerase Rpb4 Proteasome PF00227.26 EGC39692.1 - 9.7e-27 93.7 0.0 1.3e-26 93.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Act-Frag_cataly PF09192.10 EGC39692.1 - 0.03 13.7 0.1 0.043 13.2 0.1 1.1 1 0 0 1 1 1 0 Actin-fragmin kinase, catalytic Pur_ac_phosph_N PF16656.5 EGC39693.1 - 1.5e-09 38.2 0.3 3.3e-09 37.2 0.3 1.6 1 0 0 1 1 1 1 Purple acid Phosphatase, N-terminal domain Metallophos PF00149.28 EGC39693.1 - 0.00075 20.1 0.8 0.002 18.7 0.4 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase MacB_PCD PF12704.7 EGC39693.1 - 0.053 13.9 0.4 1.8 8.9 0.2 2.7 3 0 0 3 3 3 0 MacB-like periplasmic core domain Ion_trans PF00520.31 EGC39693.1 - 0.31 10.2 7.3 0.76 9.0 7.3 1.6 1 0 0 1 1 1 0 Ion transport protein DUF4252 PF14060.6 EGC39694.1 - 0.043 13.7 3.5 0.052 13.5 3.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4252) Homeobox_KN PF05920.11 EGC39695.1 - 4.2e-19 68.2 0.7 6.3e-19 67.6 0.7 1.3 1 0 0 1 1 1 1 Homeobox KN domain Homeodomain PF00046.29 EGC39695.1 - 2e-08 33.9 0.1 2.2e-08 33.8 0.1 1.1 1 0 0 1 1 1 1 Homeodomain HTH_3 PF01381.22 EGC39695.1 - 0.033 14.2 0.0 0.059 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Proteasome PF00227.26 EGC39696.1 - 7.2e-35 120.2 0.3 8.7e-35 119.9 0.3 1.1 1 0 0 1 1 1 1 Proteasome subunit Phage_capsid PF05065.13 EGC39696.1 - 0.0033 16.8 0.0 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 Phage capsid family Pkinase PF00069.25 EGC39697.1 - 3.7e-39 134.7 3.9 7.3e-38 130.4 1.7 3.0 2 1 0 2 2 2 1 Protein kinase domain FNIP PF05725.12 EGC39697.1 - 5.6e-18 64.8 21.3 1.7e-11 44.1 2.6 7.9 7 1 2 9 9 9 4 FNIP Repeat Pkinase_Tyr PF07714.17 EGC39697.1 - 3.8e-17 62.4 0.1 1.3e-15 57.4 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC39697.1 - 1.3e-05 24.1 0.0 2.3e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Fungal protein kinase Kdo PF06293.14 EGC39697.1 - 0.014 14.8 0.1 0.028 13.8 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.25 EGC39698.1 - 0.00063 19.2 0.2 0.0019 17.6 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain FNIP PF05725.12 EGC39698.1 - 0.0011 19.0 2.5 0.063 13.4 0.2 4.8 3 1 3 6 6 6 3 FNIP Repeat FDX-ACB PF03147.14 EGC39698.1 - 0.064 13.7 0.0 0.16 12.4 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain AbfS_sensor PF18225.1 EGC39698.1 - 0.089 12.7 0.0 0.31 11.0 0.0 1.9 2 0 0 2 2 2 0 Sensor histidine kinase (AbfS) sensor domain Pkinase PF00069.25 EGC39699.1 - 3.6e-116 387.2 24.4 1.9e-49 168.4 6.5 5.0 3 3 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39699.1 - 1.5e-55 188.3 11.5 4.8e-22 78.5 2.8 5.1 3 3 0 3 3 3 3 Protein tyrosine kinase FNIP PF05725.12 EGC39699.1 - 1.9e-41 140.0 106.9 4.9e-11 42.6 2.6 14.1 12 2 3 15 15 15 10 FNIP Repeat Kdo PF06293.14 EGC39699.1 - 4.8e-17 62.0 0.4 4.1e-06 26.3 0.1 3.3 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC39699.1 - 1.2e-11 44.1 12.6 2.7e-05 23.1 1.0 5.4 5 1 0 6 6 6 3 Fungal protein kinase APH PF01636.23 EGC39699.1 - 0.00018 21.5 0.0 0.13 12.2 0.0 3.1 3 0 0 3 3 3 1 Phosphotransferase enzyme family Kinase-like PF14531.6 EGC39699.1 - 0.00035 20.0 0.1 0.39 10.0 0.0 2.8 3 0 0 3 3 3 2 Kinase-like YrbL-PhoP_reg PF10707.9 EGC39699.1 - 0.013 15.1 6.3 8 5.9 0.1 3.5 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL FNIP PF05725.12 EGC39700.1 - 1.8e-41 140.1 9.5 1.5e-15 57.1 0.1 3.3 2 1 1 4 4 4 3 FNIP Repeat Peptidase_S78 PF04586.17 EGC39700.1 - 0.012 15.8 0.0 3.6 7.7 0.0 2.2 1 1 1 2 2 2 0 Caudovirus prohead serine protease FNIP PF05725.12 EGC39701.1 - 2.9e-126 411.4 35.2 8.5e-15 54.7 0.0 6.7 1 1 8 10 10 10 10 FNIP Repeat LRR_1 PF00560.33 EGC39701.1 - 0.84 10.4 8.8 1.5e+02 3.6 0.0 6.0 6 2 0 6 6 6 0 Leucine Rich Repeat EnY2 PF10163.9 EGC39702.1 - 0.012 16.0 0.1 0.034 14.5 0.1 1.8 1 0 0 1 1 1 0 Transcription factor e(y)2 TIR-like PF10137.9 EGC39702.1 - 0.031 14.2 0.4 0.16 11.9 0.0 2.3 2 0 0 2 2 2 0 Predicted nucleotide-binding protein containing TIR-like domain F-box PF00646.33 EGC39702.1 - 0.097 12.6 0.2 2.1 8.4 0.0 3.1 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.7 EGC39702.1 - 0.14 12.0 0.9 0.71 9.8 0.1 2.4 2 0 0 2 2 2 0 F-box-like DUF5423 PF17461.2 EGC39703.1 - 0.31 9.9 6.4 0.44 9.3 6.4 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Macoilin PF09726.9 EGC39703.1 - 1.3 7.5 7.2 1.4 7.4 7.2 1.2 1 0 0 1 1 1 0 Macoilin family Orf78 PF06024.12 EGC39703.1 - 9.2 6.6 8.0 12 6.3 0.3 3.0 2 1 0 2 2 2 0 Orf78 (ac78) L51_S25_CI-B8 PF05047.16 EGC39704.1 - 5.8e-10 38.9 0.0 1.1e-09 38.0 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain DUF1554 PF07588.11 EGC39704.1 - 0.022 14.6 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1554) SR-25 PF10500.9 EGC39705.1 - 0.00013 21.7 25.2 0.00013 21.7 25.2 7.6 5 2 3 8 8 8 1 Nuclear RNA-splicing-associated protein SAP PF02037.27 EGC39705.1 - 0.00061 19.5 0.0 0.0015 18.3 0.0 1.6 1 0 0 1 1 1 1 SAP domain Mut7-C PF01927.16 EGC39705.1 - 0.37 10.9 13.7 0.44 10.6 3.8 3.7 2 1 0 3 3 3 0 Mut7-C RNAse domain zf-RING_2 PF13639.6 EGC39706.1 - 2.9e-09 37.1 9.8 5.6e-09 36.2 9.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39706.1 - 1.2e-08 34.7 7.5 2.2e-08 33.8 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39706.1 - 3.4e-08 33.2 9.0 6.3e-08 32.3 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39706.1 - 1.3e-06 28.1 11.1 1.3e-06 28.1 11.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC39706.1 - 3.9e-05 23.6 5.0 9.2e-05 22.4 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC39706.1 - 0.0004 20.3 8.9 0.0004 20.3 8.9 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC39706.1 - 0.00047 19.9 9.5 0.0012 18.6 9.5 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.7 EGC39706.1 - 0.00078 19.7 5.9 0.0028 17.9 5.9 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC39706.1 - 0.0032 17.3 8.2 0.014 15.2 8.1 2.1 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC39706.1 - 0.0036 17.0 7.3 0.0075 16.0 7.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-C3HC4_4 PF15227.6 EGC39706.1 - 0.005 17.0 9.2 0.023 14.8 9.2 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.6 EGC39706.1 - 0.046 13.6 1.7 0.11 12.4 1.7 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGC39706.1 - 0.14 12.2 1.5 0.3 11.2 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Zn_ribbon_17 PF17120.5 EGC39706.1 - 0.47 10.1 5.0 0.94 9.1 5.0 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-MIZ PF02891.20 EGC39706.1 - 1 9.2 7.4 2.2 8.1 7.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.7 EGC39706.1 - 2.5 8.2 8.4 14 5.8 8.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon EGF_2 PF07974.13 EGC39708.1 - 2.2e-05 24.7 7.0 4.7e-05 23.7 7.0 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.24 EGC39708.1 - 0.00091 19.3 7.8 0.0015 18.6 7.8 1.4 1 0 0 1 1 1 1 Laminin EGF domain EGF_Tenascin PF18720.1 EGC39708.1 - 0.0024 17.8 4.5 0.0049 16.9 4.5 1.5 1 1 0 1 1 1 1 Tenascin EGF domain EGF_alliinase PF04863.13 EGC39708.1 - 0.071 13.5 5.5 0.15 12.5 5.5 1.6 1 1 0 1 1 1 0 Alliinase EGF-like domain zf-C2H2_jaz PF12171.8 EGC39709.1 - 8.7e-09 35.4 3.3 8.7e-09 35.4 3.3 3.1 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.7 EGC39709.1 - 3.4e-06 27.3 5.7 1e-05 25.7 2.4 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.7 EGC39709.1 - 0.0035 17.7 3.1 0.0044 17.3 0.3 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.6 EGC39709.1 - 0.014 16.2 0.7 0.014 16.2 0.7 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.6 EGC39709.1 - 0.022 14.8 1.0 0.022 14.8 1.0 3.1 3 0 0 3 3 3 0 C2H2-type zinc finger zf-Di19 PF05605.12 EGC39709.1 - 0.11 12.8 0.2 0.24 11.7 0.2 1.6 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Equine_IAV_S2 PF06502.11 EGC39709.1 - 0.32 11.1 6.6 0.85 9.7 0.9 3.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein DUF1967 PF09269.11 EGC39709.1 - 0.37 10.8 4.9 2.4 8.2 0.6 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1967) zf-DBF PF07535.12 EGC39709.1 - 0.93 9.7 5.6 0.28 11.3 1.2 2.5 2 0 0 2 2 2 0 DBF zinc finger FixO PF02433.15 EGC39709.1 - 3.9 6.9 6.9 1.2 8.6 1.5 2.6 2 0 0 2 2 2 0 Cytochrome C oxidase, mono-heme subunit/FixO MscS_TM PF12794.7 EGC39709.1 - 4.5 6.0 4.9 1.2 7.9 0.5 2.1 2 0 0 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 RasGAP PF00616.19 EGC39710.1 - 4e-34 118.2 0.3 3.9e-26 92.0 0.1 4.7 2 2 2 4 4 4 2 GTPase-activator protein for Ras-like GTPase Bromodomain PF00439.25 EGC39711.1 - 2.2e-19 69.3 0.1 4.2e-19 68.4 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_1 PF00583.25 EGC39711.1 - 2.8e-10 40.5 0.0 5.1e-10 39.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.7 EGC39711.1 - 6.9e-06 26.0 0.0 1.2e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.7 EGC39711.1 - 5.5e-05 23.5 0.1 0.00025 21.4 0.2 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Arf PF00025.21 EGC39712.1 - 6.3e-46 156.0 0.1 7.7e-46 155.7 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.22 EGC39712.1 - 1.1e-20 73.9 0.0 1.3e-20 73.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39712.1 - 2.3e-17 63.3 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Gtr1_RagA PF04670.12 EGC39712.1 - 7e-12 45.2 0.0 8e-12 45.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.20 EGC39712.1 - 3.2e-09 36.4 0.6 4.5e-06 26.1 0.0 2.4 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.23 EGC39712.1 - 1.4e-08 34.8 0.0 2e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.10 EGC39712.1 - 3.3e-08 33.2 0.0 4.2e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit RsgA_GTPase PF03193.16 EGC39712.1 - 0.00067 19.6 0.5 0.51 10.2 0.1 2.1 2 0 0 2 2 2 2 RsgA GTPase ATP_bind_1 PF03029.17 EGC39712.1 - 0.0023 17.8 0.2 1.9 8.2 0.2 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein AAA_7 PF12775.7 EGC39712.1 - 0.0026 17.3 0.0 0.0036 16.8 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region GTP_EFTU PF00009.27 EGC39712.1 - 0.003 17.1 0.1 0.036 13.6 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain NACHT PF05729.12 EGC39712.1 - 0.0032 17.4 0.0 1.1 9.2 0.0 2.1 2 0 0 2 2 2 2 NACHT domain ABC_tran PF00005.27 EGC39712.1 - 0.0056 17.2 0.5 0.0063 17.0 0.5 1.4 1 1 0 1 1 1 1 ABC transporter cobW PF02492.19 EGC39712.1 - 0.01 15.5 2.5 0.46 10.0 0.1 2.4 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.6 EGC39712.1 - 0.013 15.8 0.0 0.58 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.6 EGC39712.1 - 0.045 14.3 0.1 0.065 13.8 0.1 1.4 1 1 0 1 1 1 0 AAA domain NB-ARC PF00931.22 EGC39712.1 - 0.059 12.5 0.0 0.11 11.7 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain VirE PF05272.11 EGC39712.1 - 0.077 12.7 0.1 0.12 12.0 0.1 1.3 1 0 0 1 1 1 0 Virulence-associated protein E MMR_HSR1_Xtn PF16897.5 EGC39712.1 - 0.11 12.6 0.4 0.2 11.7 0.4 1.5 1 1 0 1 1 1 0 C-terminal region of MMR_HSR1 domain AAA_22 PF13401.6 EGC39712.1 - 0.12 12.7 0.2 1.7 8.9 0.2 2.1 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.15 EGC39712.1 - 0.21 11.5 1.2 0.45 10.4 0.6 1.6 1 1 0 2 2 2 0 NTPase AAA_33 PF13671.6 EGC39712.1 - 0.23 11.6 0.2 0.41 10.8 0.2 1.4 1 0 0 1 1 1 0 AAA domain MFS_1 PF07690.16 EGC39714.1 - 2.5e-38 131.9 36.9 2.2e-25 89.3 14.8 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily UCH PF00443.29 EGC39715.1 - 3.5e-80 269.2 0.0 3.1e-79 266.1 0.0 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.12 EGC39715.1 - 6.6e-22 77.9 1.7 6.6e-22 77.9 1.7 3.8 5 0 0 5 5 5 1 DUSP domain UCH_1 PF13423.6 EGC39715.1 - 2.2e-08 34.1 25.0 0.00022 21.0 0.6 4.3 3 1 0 4 4 4 3 Ubiquitin carboxyl-terminal hydrolase DUF3780 PF12635.7 EGC39715.1 - 0.038 13.8 1.2 0.075 12.8 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3780) zf-RRPl_C4 PF17026.5 EGC39715.1 - 1.3 9.1 6.8 2.4 8.3 0.2 3.1 3 0 0 3 3 3 0 Putative ribonucleoprotein zinc-finger pf C4 type MID_MedPIWI PF18296.1 EGC39715.1 - 5.6 6.7 13.1 1.2 8.9 1.7 2.6 2 1 0 2 2 2 0 MID domain of medPIWI zf_UBZ PF18439.1 EGC39715.1 - 9.2 6.0 10.1 0.35 10.5 0.2 2.7 3 0 0 3 3 3 0 Ubiquitin-Binding Zinc Finger HMA PF00403.26 EGC39716.1 - 8.7e-13 48.5 0.8 1.2e-12 48.1 0.8 1.2 1 0 0 1 1 1 1 Heavy-metal-associated domain Fer2_BFD PF04324.15 EGC39716.1 - 0.034 14.5 0.1 0.081 13.3 0.0 1.6 2 0 0 2 2 2 0 BFD-like [2Fe-2S] binding domain NLRC4_HD PF17889.1 EGC39716.1 - 0.048 14.0 0.0 0.05 13.9 0.0 1.1 1 0 0 1 1 1 0 NLRC4 helical domain HAUS2 PF15003.6 EGC39716.1 - 0.05 13.3 0.1 0.052 13.3 0.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 2 zf-TRAF PF02176.18 EGC39717.1 - 1.2e-16 61.2 15.6 2.9e-11 43.9 5.0 4.1 2 1 2 4 4 4 2 TRAF-type zinc finger zf-TRAF_2 PF15965.5 EGC39717.1 - 1.2e-05 25.7 24.7 0.0023 18.3 2.5 4.1 1 1 3 4 4 4 3 TRAF-like zinc-finger Sina PF03145.16 EGC39717.1 - 0.00021 21.3 26.4 0.0015 18.5 1.7 3.5 2 1 2 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.6 EGC39717.1 - 0.00065 19.5 5.5 0.00065 19.5 5.5 3.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF325 PF03804.13 EGC39717.1 - 0.15 12.1 0.7 0.37 10.8 0.6 1.8 1 1 0 1 1 1 0 Viral proteins of unknown function zf_UBZ PF18439.1 EGC39717.1 - 1.6 8.4 0.0 1.6 8.4 0.0 4.3 5 0 0 5 5 5 0 Ubiquitin-Binding Zinc Finger zf-TRAF PF02176.18 EGC39719.1 - 1.1e-13 51.6 20.7 1.9e-08 34.9 7.7 4.2 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.16 EGC39719.1 - 9.7e-05 22.4 13.5 0.0017 18.3 1.9 3.9 2 1 2 4 4 4 3 Seven in absentia protein family zf-TRAF_2 PF15965.5 EGC39719.1 - 0.00011 22.7 8.7 0.00011 22.7 8.7 4.4 1 1 3 4 4 4 2 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 EGC39719.1 - 0.00012 21.9 11.0 0.00012 21.9 11.0 3.9 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39719.1 - 0.001 18.9 13.6 0.001 18.9 13.6 3.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) JIP_LZII PF16471.5 EGC39719.1 - 1.7 8.9 10.5 0.28 11.4 5.2 2.6 3 0 0 3 3 3 0 JNK-interacting protein leucine zipper II MAP65_ASE1 PF03999.12 EGC39720.1 - 1.2e-28 100.3 99.1 6.5e-22 78.0 36.6 3.9 1 1 2 3 3 3 3 Microtubule associated protein (MAP65/ASE1 family) DUF2789 PF10982.8 EGC39720.1 - 0.45 10.7 8.4 9.8 6.4 0.3 4.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2789) CAF1 PF04857.20 EGC39721.1 - 8.8e-23 81.0 1.3 6e-12 45.4 0.1 2.6 1 1 1 2 2 2 2 CAF1 family ribonuclease RFX_DNA_binding PF02257.15 EGC39721.1 - 0.047 14.3 0.1 0.86 10.3 0.0 2.7 3 0 0 3 3 3 0 RFX DNA-binding domain Pkinase PF00069.25 EGC39722.1 - 1.9e-69 234.0 0.0 3e-69 233.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39722.1 - 2.7e-52 177.6 0.0 3.7e-52 177.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC39722.1 - 5.4e-08 32.0 0.0 1.3e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Fungal protein kinase Mst1_SARAH PF11629.8 EGC39722.1 - 0.002 18.2 1.6 0.002 18.2 1.6 2.2 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 VPS9 PF02204.18 EGC39723.1 - 6.9e-15 55.1 0.2 2.1e-14 53.6 0.2 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ubiquitin PF00240.23 EGC39724.1 - 5.7e-10 38.8 0.3 5.8e-10 38.8 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC39724.1 - 7.8e-06 25.6 0.7 1.2e-05 25.1 0.7 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC39724.1 - 0.00019 21.8 0.3 0.00072 20.0 0.3 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain Kindlin_2_N PF18124.1 EGC39724.1 - 0.014 15.6 0.2 0.041 14.1 0.2 1.7 1 1 0 1 1 1 0 Kindlin-2 N-terminal domain UAE_UbL PF14732.6 EGC39724.1 - 0.033 14.8 0.1 0.046 14.3 0.1 1.3 1 1 0 1 1 1 0 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Ubiquitin_4 PF18036.1 EGC39724.1 - 0.065 13.3 0.6 0.86 9.7 0.1 2.0 1 1 1 2 2 2 0 Ubiquitin-like domain RAWUL PF16207.5 EGC39724.1 - 0.17 12.6 0.1 0.26 12.0 0.1 1.4 1 1 0 1 1 1 0 RAWUL domain RING finger- and WD40-associated ubiquitin-like Aminotran_5 PF00266.19 EGC39725.1 - 1.7e-14 53.6 0.0 2.3e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.20 EGC39725.1 - 0.0099 14.4 0.0 0.013 14.1 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme SHMT PF00464.19 EGC39725.1 - 0.06 11.9 0.0 0.087 11.4 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase DUF4811 PF16069.5 EGC39726.1 - 0.0097 15.8 0.4 0.016 15.1 0.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4811) CUE PF02845.16 EGC39726.1 - 0.098 12.4 0.0 0.21 11.3 0.0 1.6 1 0 0 1 1 1 0 CUE domain DUF1802 PF08819.11 EGC39726.1 - 0.16 11.8 0.0 0.21 11.5 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1802) COBRA1 PF06209.13 EGC39727.1 - 3.4e-70 237.3 5.3 3.4e-70 237.3 5.3 2.1 2 0 0 2 2 2 1 Cofactor of BRCA1 (COBRA1) CK_II_beta PF01214.18 EGC39727.1 - 0.046 13.5 2.7 0.088 12.6 1.0 2.3 2 0 0 2 2 2 0 Casein kinase II regulatory subunit DUF4175 PF13779.6 EGC39727.1 - 0.56 8.1 7.6 0.79 7.6 7.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF1772 PF08592.11 EGC39728.1 - 0.0016 18.8 0.1 0.0019 18.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) TssO PF17561.2 EGC39728.1 - 0.091 12.9 0.8 0.21 11.7 0.8 1.6 1 0 0 1 1 1 0 Type VI secretion system, TssO Erf4 PF10256.9 EGC39729.1 - 0.0022 18.1 0.6 0.039 14.0 0.6 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.9 EGC39730.1 - 0.0046 15.8 4.0 0.0056 15.5 4.0 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) ABC_membrane_3 PF13748.6 EGC39730.1 - 0.066 12.4 2.7 0.095 11.9 2.7 1.2 1 0 0 1 1 1 0 ABC transporter transmembrane region CSTF2_hinge PF14327.6 EGC39730.1 - 0.12 12.9 0.1 0.21 12.1 0.1 1.3 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 DUF4191 PF13829.6 EGC39730.1 - 0.75 9.1 3.0 1.1 8.6 3.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) FNIP PF05725.12 EGC39732.1 - 8e-86 282.0 39.3 5.1e-15 55.3 0.2 8.0 3 3 5 9 9 9 9 FNIP Repeat Peptidase_S78 PF04586.17 EGC39732.1 - 0.0055 16.9 0.0 19 5.4 0.0 4.1 1 1 2 4 4 4 2 Caudovirus prohead serine protease Ras PF00071.22 EGC39733.1 - 6.5e-33 113.6 0.1 7.4e-33 113.4 0.1 1.0 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39733.1 - 1.3e-21 77.0 0.2 1.8e-21 76.6 0.2 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39733.1 - 3.3e-12 46.2 0.2 4e-12 45.9 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39733.1 - 2.6e-08 33.5 0.0 3e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC39733.1 - 0.00012 21.7 0.7 0.3 10.6 0.1 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.9 EGC39733.1 - 0.0027 17.5 0.1 0.048 13.4 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.10 EGC39733.1 - 0.007 15.8 0.0 0.011 15.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_7 PF12775.7 EGC39733.1 - 0.0082 15.7 0.0 0.015 14.9 0.0 1.3 1 0 0 1 1 1 1 P-loop containing dynein motor region MMR_HSR1 PF01926.23 EGC39733.1 - 0.011 15.8 0.1 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.6 EGC39733.1 - 0.037 13.7 0.1 0.045 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.6 EGC39733.1 - 0.066 13.8 0.0 0.12 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ResIII PF04851.15 EGC39733.1 - 0.068 13.2 0.0 0.86 9.6 0.0 2.0 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit TsaE PF02367.17 EGC39733.1 - 0.075 13.0 0.0 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE ATP_bind_1 PF03029.17 EGC39733.1 - 0.095 12.5 0.1 0.85 9.4 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_16 PF13191.6 EGC39733.1 - 0.18 12.2 0.0 0.29 11.5 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain Sigma54_activat PF00158.26 EGC39733.1 - 0.19 11.4 0.0 0.3 10.8 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain TPR_1 PF00515.28 EGC39734.1 - 5.8e-14 51.2 4.8 1.4e-06 27.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39734.1 - 9e-13 47.3 1.0 2e-05 24.4 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.6 EGC39734.1 - 1.1e-06 28.9 0.6 0.0088 16.3 0.1 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_11 PF13414.6 EGC39734.1 - 1.2e-06 28.1 3.5 0.0044 16.7 0.3 2.7 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.6 EGC39734.1 - 4.2e-05 24.1 0.6 0.0023 18.5 0.5 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC39734.1 - 0.00043 20.9 0.1 0.073 13.9 0.1 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39734.1 - 0.00074 19.5 7.2 0.015 15.5 0.1 3.6 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_9 PF13371.6 EGC39734.1 - 0.0072 16.5 0.0 0.013 15.6 0.0 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC39734.1 - 0.016 15.2 0.9 2.1 8.6 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.6 EGC39734.1 - 0.038 13.9 0.4 4.2 7.4 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC39734.1 - 0.12 13.0 0.5 2.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SHNi-TPR PF10516.9 EGC39734.1 - 0.33 10.4 2.7 13 5.3 0.0 3.4 3 0 0 3 3 3 0 SHNi-TPR MIT PF04212.18 EGC39734.1 - 0.46 10.6 8.3 0.64 10.1 0.4 3.0 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain CtIP_N PF10482.9 EGC39736.1 - 0.0031 17.6 7.9 0.0031 17.6 7.9 3.1 1 1 2 3 3 3 2 Tumour-suppressor protein CtIP N-terminal domain Neur_chan_memb PF02932.16 EGC39736.1 - 0.32 11.0 3.6 0.38 10.8 3.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4044 PF13253.6 EGC39736.1 - 2.4 7.7 3.8 0.6 9.7 0.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4044) SMAP PF15477.6 EGC39736.1 - 3.8 8.5 10.2 2.6 9.1 4.8 2.3 2 0 0 2 2 2 0 Small acidic protein family DUF4446 PF14584.6 EGC39736.1 - 4.6 7.2 14.9 3 7.8 1.9 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF4446) Glyco_hydro_47 PF01532.20 EGC39737.1 - 1.9e-40 139.2 0.0 3.2e-39 135.1 0.0 1.9 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 Kinase-PolyVal PF18762.1 EGC39737.1 - 0.016 15.1 0.1 0.033 14.1 0.1 1.5 1 0 0 1 1 1 0 Serine/Threonine/Tyrosine Kinase found in polyvalent proteins Pepsin-I3 PF06394.13 EGC39738.1 - 0.19 11.9 4.4 61 3.9 0.1 4.3 3 0 0 3 3 3 0 Pepsin inhibitor-3-like repeated domain NusG_II PF07009.11 EGC39739.1 - 0.0093 16.2 0.1 0.044 14.0 0.0 1.9 1 1 1 2 2 2 1 NusG domain II Inhibitor_I53 PF11714.8 EGC39739.1 - 0.5 10.6 7.6 1.2 9.4 7.6 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Glyco_hydro_47 PF01532.20 EGC39740.1 - 2e-47 162.1 0.1 2.6e-47 161.8 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.14 EGC39740.1 - 0.0088 15.6 0.0 0.31 10.5 0.0 2.0 2 0 0 2 2 2 2 Glycosyl hydrolase family 76 YL1 PF05764.13 EGC39742.1 - 0.0063 16.7 8.7 0.0085 16.2 8.7 1.2 1 0 0 1 1 1 1 YL1 nuclear protein NOA36 PF06524.12 EGC39742.1 - 0.011 15.1 7.5 0.011 15.1 7.5 1.9 2 0 0 2 2 2 0 NOA36 protein PTPRCAP PF15713.5 EGC39742.1 - 0.023 15.0 3.4 0.032 14.5 3.4 1.4 1 0 0 1 1 1 0 Protein tyrosine phosphatase receptor type C-associated TRAP_alpha PF03896.16 EGC39742.1 - 0.08 12.1 3.2 0.13 11.5 3.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit FAM176 PF14851.6 EGC39742.1 - 0.31 10.7 7.9 0.11 12.1 5.1 1.6 2 0 0 2 2 2 0 FAM176 family CDC45 PF02724.14 EGC39742.1 - 0.57 8.4 9.8 0.85 7.8 9.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.11 EGC39742.1 - 7.5 4.5 10.2 11 4.0 10.2 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Astro_capsid_p PF12226.8 EGC39742.1 - 9.4 5.3 9.6 16 4.5 9.6 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein CtIP_N PF10482.9 EGC39743.1 - 0.0053 16.8 7.9 0.0053 16.8 7.9 3.0 1 1 2 3 3 3 2 Tumour-suppressor protein CtIP N-terminal domain SLC12 PF03522.15 EGC39743.1 - 0.14 11.1 16.2 0.17 10.9 16.2 1.0 1 0 0 1 1 1 0 Solute carrier family 12 Neur_chan_memb PF02932.16 EGC39743.1 - 0.42 10.6 3.9 0.49 10.4 3.9 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4446 PF14584.6 EGC39743.1 - 2.7 7.9 17.3 0.52 10.3 1.6 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) CtIP_N PF10482.9 EGC39744.1 - 0.0047 17.0 7.9 0.0047 17.0 7.9 3.0 1 1 2 3 3 3 2 Tumour-suppressor protein CtIP N-terminal domain SLC12 PF03522.15 EGC39744.1 - 0.13 11.3 16.3 0.15 11.1 16.3 1.0 1 0 0 1 1 1 0 Solute carrier family 12 DUF4446 PF14584.6 EGC39744.1 - 3.8 7.5 17.0 1.1 9.2 2.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) PMI_typeI PF01238.21 EGC39745.1 - 1.4e-95 320.7 0.0 1.5e-94 317.3 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.11 EGC39745.1 - 0.00071 19.2 0.0 0.58 9.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.19 EGC39745.1 - 0.017 15.0 0.0 3.6 7.5 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain Mid2 PF04478.12 EGC39746.1 - 0.016 15.1 0.5 0.036 13.9 0.5 1.5 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor LRR_6 PF13516.6 EGC39747.1 - 2.3e-12 45.9 35.5 0.28 11.3 0.2 10.7 12 1 1 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.7 EGC39747.1 - 8e-08 32.5 34.1 0.17 12.4 4.6 7.9 4 4 4 8 8 8 5 Leucine Rich repeats (2 copies) FRQ PF09421.10 EGC39747.1 - 0.071 11.1 0.0 0.089 10.8 0.0 1.1 1 0 0 1 1 1 0 Frequency clock protein LRR_1 PF00560.33 EGC39747.1 - 0.35 11.6 31.1 7.5 7.5 0.0 8.8 9 1 0 9 9 9 0 Leucine Rich Repeat LRR_8 PF13855.6 EGC39747.1 - 2.9 7.7 31.1 2 8.2 0.2 8.3 5 2 4 9 9 9 0 Leucine rich repeat COX6B PF02297.17 EGC39748.1 - 9.1e-19 67.5 4.5 1.1e-18 67.3 4.5 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.13 EGC39748.1 - 0.014 15.5 2.1 0.028 14.6 2.1 1.6 1 1 0 1 1 1 0 CHCH domain CX9C PF16860.5 EGC39748.1 - 0.068 13.2 1.7 0.1 12.6 1.7 1.3 1 0 0 1 1 1 0 CHCH-CHCH-like Cx9C, IMS import disulfide relay-system, PlyB_C PF18684.1 EGC39749.1 - 0.084 12.6 0.0 1.5 8.5 0.0 2.3 2 0 0 2 2 2 0 Pleurotolysin B C-terminal domain SpoIIID PF12116.8 EGC39749.1 - 0.6 10.2 5.2 2.8 8.1 0.5 2.9 3 0 0 3 3 3 0 Stage III sporulation protein D Esterase_phd PF10503.9 EGC39750.1 - 1e-05 25.2 0.1 0.00082 18.9 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase Hydrolase_4 PF12146.8 EGC39750.1 - 0.24 10.6 0.4 8.4 5.6 0.3 2.2 1 1 0 2 2 2 0 Serine aminopeptidase, S33 FNIP PF05725.12 EGC39751.1 - 4.3e-89 292.5 115.1 1.6e-10 40.9 1.8 12.3 6 2 10 16 16 16 16 FNIP Repeat TGT_C1 PF14809.6 EGC39751.1 - 0.0064 16.8 0.4 3.6 8.0 0.1 3.9 3 1 0 3 3 3 1 C1 domain of tRNA-guanine transglycosylase dimerisation DNMT1-RFD PF12047.8 EGC39752.1 - 0.008 16.2 8.3 0.008 16.2 8.3 3.0 2 1 1 3 3 3 1 Cytosine specific DNA methyltransferase replication foci domain Xpo1 PF08389.12 EGC39753.1 - 2.6e-21 76.3 2.5 2.6e-21 76.3 2.5 5.1 4 2 2 6 6 6 1 Exportin 1-like protein IBN_N PF03810.19 EGC39753.1 - 1.9e-06 27.7 2.0 1.9e-06 27.7 2.0 3.2 2 1 0 2 2 2 1 Importin-beta N-terminal domain Init_tRNA_PT PF04179.12 EGC39753.1 - 1.4 9.2 4.2 1.3 9.3 0.3 3.0 3 1 0 3 3 3 0 Rit1 DUSP-like domain Mo25 PF08569.11 EGC39754.1 - 2.8e-136 454.2 16.3 3.2e-136 454.0 16.3 1.0 1 0 0 1 1 1 1 Mo25-like Occludin_ELL PF07303.13 EGC39754.1 - 0.22 12.3 3.4 3.2 8.5 0.0 2.9 3 0 0 3 3 3 0 Occludin homology domain DNA_repr_REX1B PF14966.6 EGC39755.1 - 1.9e-24 86.2 1.9 1.9e-24 86.2 1.9 2.1 2 0 0 2 2 2 1 DNA repair REX1-B SMC_Nse1 PF07574.13 EGC39755.1 - 0.0029 17.5 3.4 0.063 13.2 0.3 2.2 1 1 0 2 2 2 2 Nse1 non-SMC component of SMC5-6 complex KMP11 PF03037.16 EGC39755.1 - 0.017 15.9 5.2 0.15 12.9 0.7 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 FlxA PF14282.6 EGC39755.1 - 0.085 12.9 7.1 0.46 10.5 1.0 2.7 2 2 0 2 2 2 0 FlxA-like protein Lectin_N PF03954.14 EGC39755.1 - 0.4 10.4 5.6 0.38 10.5 0.3 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain Laminin_II PF06009.12 EGC39755.1 - 1.8 8.6 7.2 2.5 8.1 2.8 2.2 2 0 0 2 2 2 0 Laminin Domain II HIP1_clath_bdg PF16515.5 EGC39755.1 - 2 9.0 6.7 1.6 9.4 0.8 2.7 2 2 1 3 3 3 0 Clathrin-binding domain of Huntingtin-interacting protein 1 BRE1 PF08647.11 EGC39755.1 - 2.3 8.3 9.5 0.044 13.8 1.4 2.3 2 1 1 3 3 3 0 BRE1 E3 ubiquitin ligase Jnk-SapK_ap_N PF09744.9 EGC39755.1 - 3.7 7.8 10.5 1.1 9.4 2.5 2.4 1 1 1 2 2 2 0 JNK_SAPK-associated protein-1 DUF4665 PF15679.5 EGC39755.1 - 9.1 7.0 8.1 2.3 8.9 0.7 2.9 2 1 0 2 2 2 0 Domain of unknown function (DUF4665) Skp1_POZ PF03931.15 EGC39756.1 - 1.1e-07 31.9 0.0 2.3e-07 30.9 0.0 1.5 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain BTB PF00651.31 EGC39756.1 - 0.00033 20.9 0.1 0.00045 20.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain ProRS-C_1 PF09180.11 EGC39757.1 - 3.5e-27 94.4 4.8 1e-26 92.9 4.8 1.8 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.20 EGC39757.1 - 9.1e-22 77.0 0.0 1.9e-21 76.0 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.25 EGC39757.1 - 3.1e-18 66.4 0.0 6.1e-18 65.4 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) SYF2 PF08231.12 EGC39758.1 - 2.8e-23 83.1 18.2 2.8e-23 83.1 18.2 2.8 1 1 1 2 2 2 1 SYF2 splicing factor DUF1178 PF06676.11 EGC39758.1 - 0.26 11.7 11.0 0.035 14.5 5.9 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1178) NAM PF02365.15 EGC39760.1 - 0.0011 19.9 0.1 0.0042 18.0 0.0 1.8 2 0 0 2 2 2 1 No apical meristem (NAM) protein RHS PF03527.14 EGC39760.1 - 0.0062 16.3 0.0 0.0062 16.3 0.0 1.9 2 0 0 2 2 2 1 RHS protein TPR_2 PF07719.17 EGC39762.1 - 4e-09 35.9 11.5 5.9e-05 22.9 0.6 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39762.1 - 4.3e-09 35.8 8.4 1.3e-05 24.8 0.5 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat SET PF00856.28 EGC39762.1 - 9e-09 35.9 1.3 9e-09 35.9 1.3 2.8 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.18 EGC39762.1 - 2.2e-05 24.5 10.1 2.2e-05 24.5 10.1 2.1 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.6 EGC39762.1 - 0.00047 20.4 1.8 1.5 9.2 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_16 PF13432.6 EGC39762.1 - 0.00074 20.1 0.0 0.5 11.1 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC39762.1 - 0.13 13.2 0.0 16 6.7 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC39762.1 - 0.85 10.0 11.4 3.4 8.1 0.3 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat RNase_PH PF01138.21 EGC39763.1 - 2.8e-23 82.9 0.3 4.3e-23 82.3 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.15 EGC39763.1 - 6.1e-07 29.4 0.4 1.4e-06 28.2 0.4 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF3246 PF11596.8 EGC39763.1 - 0.15 11.4 0.7 1.8 7.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) Nop14 PF04147.12 EGC39764.1 - 1.6 6.9 35.0 2.2 6.4 35.0 1.1 1 0 0 1 1 1 0 Nop14-like family GRP PF07172.11 EGC39764.1 - 3.7 8.3 0.0 3.7 8.3 0.0 2.7 3 1 0 3 3 3 0 Glycine rich protein family CDC45 PF02724.14 EGC39764.1 - 5.8 5.1 25.4 10 4.2 25.4 1.3 1 0 0 1 1 1 0 CDC45-like protein AC_N PF16214.5 EGC39764.1 - 6.7 5.7 6.5 9 5.3 5.6 1.6 2 0 0 2 2 2 0 Adenylyl cyclase N-terminal extracellular and transmembrane region FNIP PF05725.12 EGC39765.1 - 2e-21 75.8 63.9 2.5e-06 27.5 0.2 12.0 7 3 5 12 12 12 9 FNIP Repeat Ras PF00071.22 EGC39766.1 - 8.7e-45 152.2 0.1 1.1e-44 151.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39766.1 - 1.1e-28 99.9 0.1 1.5e-28 99.4 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39766.1 - 5.5e-10 39.0 0.1 7e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39766.1 - 5.1e-07 29.3 0.0 6.1e-07 29.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.9 EGC39766.1 - 0.00014 21.7 0.0 0.0025 17.5 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation TniB PF05621.11 EGC39766.1 - 0.00084 18.8 0.0 0.047 13.1 0.1 2.7 2 1 1 3 3 3 1 Bacterial TniB protein MMR_HSR1 PF01926.23 EGC39766.1 - 0.0014 18.6 0.0 0.0023 18.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_7 PF12775.7 EGC39766.1 - 0.0028 17.2 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 P-loop containing dynein motor region SRPRB PF09439.10 EGC39766.1 - 0.0053 16.2 0.0 0.016 14.6 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.27 EGC39766.1 - 0.0062 16.1 0.7 0.63 9.5 0.7 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.17 EGC39766.1 - 0.01 15.7 0.0 0.67 9.7 0.0 2.1 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein DUF4998 PF16389.5 EGC39766.1 - 0.015 14.9 0.0 0.022 14.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function TsaE PF02367.17 EGC39766.1 - 0.039 14.0 0.0 0.14 12.2 0.0 1.9 2 0 0 2 2 2 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_16 PF13191.6 EGC39766.1 - 0.057 13.8 0.0 0.12 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_24 PF13479.6 EGC39766.1 - 0.061 13.0 0.0 0.082 12.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain G-alpha PF00503.20 EGC39766.1 - 0.096 11.8 0.0 9.5 5.3 0.0 2.2 2 0 0 2 2 2 0 G-protein alpha subunit AAA PF00004.29 EGC39766.1 - 0.1 13.0 0.0 0.15 12.4 0.0 1.7 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) RsgA_GTPase PF03193.16 EGC39766.1 - 0.1 12.5 0.0 7.9 6.4 0.0 2.2 2 0 0 2 2 2 0 RsgA GTPase DLIC PF05783.11 EGC39766.1 - 0.1 11.4 0.2 3.5 6.4 0.1 2.0 2 0 0 2 2 2 0 Dynein light intermediate chain (DLIC) AAA_22 PF13401.6 EGC39766.1 - 0.13 12.5 0.0 0.21 11.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.22 EGC39766.1 - 0.15 11.7 0.0 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain DUF815 PF05673.13 EGC39766.1 - 0.16 11.1 0.0 0.51 9.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) Proteasome PF00227.26 EGC39767.1 - 2.2e-48 164.2 0.9 2.7e-48 164.0 0.9 1.1 1 0 0 1 1 1 1 Proteasome subunit LIM PF00412.22 EGC39768.1 - 2.8e-21 75.5 32.9 3.9e-09 36.6 4.2 3.5 2 1 0 3 3 3 3 LIM domain STAG PF08514.11 EGC39769.1 - 2.2e-19 69.4 0.8 2.2e-19 69.4 0.8 3.6 2 1 1 3 3 3 1 STAG domain Pox_Ag35 PF03286.14 EGC39769.1 - 0.86 9.4 44.3 0.14 12.0 20.1 3.9 3 0 0 3 3 3 0 Pox virus Ag35 surface protein AAA_11 PF13086.6 EGC39771.1 - 2.3e-17 63.6 0.1 4.1e-07 30.1 0.0 3.0 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.6 EGC39771.1 - 5.1e-14 52.4 1.0 5.1e-14 52.4 1.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.6 EGC39771.1 - 3.1e-11 43.3 0.0 5.9e-11 42.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.6 EGC39771.1 - 7.8e-11 42.5 0.0 2.2e-10 41.0 0.0 1.8 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.18 EGC39771.1 - 3.1e-07 30.4 0.1 0.008 15.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.16 EGC39771.1 - 0.00041 19.9 0.0 0.068 12.6 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein DEAD PF00270.29 EGC39771.1 - 0.0013 18.6 0.0 0.0034 17.2 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_RecD PF05127.14 EGC39771.1 - 0.0057 16.5 0.0 0.016 15.1 0.0 1.8 1 0 0 1 1 1 1 Helicase Casein_kappa PF00997.18 EGC39771.1 - 7.5 6.6 17.7 7.4 6.6 0.0 3.3 3 0 0 3 3 3 0 Kappa casein SIN1_PH PF16979.5 EGC39772.1 - 1e-10 41.8 1.1 3.8e-10 40.0 1.1 2.1 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), Pleckstrin-homology CRIM PF16978.5 EGC39772.1 - 5.1e-07 29.9 0.0 1.6e-06 28.3 0.0 1.8 1 0 0 1 1 1 1 SAPK-interacting protein 1 (Sin1), middle CRIM domain RBD PF02196.15 EGC39772.1 - 2.7e-06 27.4 0.1 9.6e-06 25.6 0.1 2.0 1 0 0 1 1 1 1 Raf-like Ras-binding domain CDK2AP PF09806.9 EGC39772.1 - 0.0073 16.4 9.4 0.0073 16.4 9.4 2.7 2 1 0 2 2 2 1 Cyclin-dependent kinase 2-associated protein TFIIA PF03153.13 EGC39772.1 - 0.0098 15.9 54.2 0.07 13.1 30.6 2.2 2 0 0 2 2 2 2 Transcription factor IIA, alpha/beta subunit TUG-UBL1 PF11470.8 EGC39772.1 - 0.51 10.6 0.1 0.51 10.6 0.1 2.9 4 0 0 4 4 4 0 TUG ubiquitin-like domain Methuselah_N PF06652.12 EGC39772.1 - 3.4 7.6 0.0 3.4 7.6 0.0 3.0 4 0 0 4 4 4 0 Methuselah N-terminus PLDc_2 PF13091.6 EGC39773.1 - 6.7e-36 123.1 0.0 6.9e-24 84.2 0.0 2.7 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.22 EGC39773.1 - 9.3e-08 31.9 6.2 3.4e-05 23.8 0.2 3.1 3 0 0 3 3 3 2 Phospholipase D Active site motif Ferritin PF00210.24 EGC39773.1 - 0.037 14.0 0.0 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 Ferritin-like domain RRM_1 PF00076.22 EGC39775.1 - 2.6e-41 139.3 0.7 8.3e-16 57.6 0.1 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.6 EGC39775.1 - 7.4e-20 71.8 0.6 7.4e-20 71.8 0.6 2.5 3 0 0 3 3 3 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_occluded PF16842.5 EGC39775.1 - 6.8e-08 32.3 0.1 0.00036 20.3 0.0 3.2 3 0 0 3 3 3 2 Occluded RNA-recognition motif RRM_5 PF13893.6 EGC39775.1 - 5.7e-07 29.2 0.5 0.00073 19.1 0.0 2.9 1 1 1 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC39775.1 - 0.00091 19.2 0.3 1.5 8.9 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.11 EGC39775.1 - 0.0011 19.0 6.4 0.021 14.9 0.0 3.6 4 0 0 4 4 4 1 RNA binding motif Limkain-b1 PF11608.8 EGC39775.1 - 0.0032 17.5 0.0 0.079 13.0 0.0 3.1 3 0 0 3 3 3 1 Limkain b1 RRM_8 PF11835.8 EGC39775.1 - 0.011 15.9 0.7 0.17 12.1 0.0 2.8 3 0 0 3 3 3 0 RRM-like domain DUF1866 PF08952.11 EGC39775.1 - 0.063 13.1 0.0 3.1 7.6 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF1866) Fcf1 PF04900.12 EGC39776.1 - 2.2e-18 66.5 0.1 7.7e-18 64.7 0.1 2.0 1 0 0 1 1 1 1 Fcf1 LptF_LptG PF03739.14 EGC39776.1 - 7.1 5.4 9.3 15 4.3 9.2 1.5 1 1 0 1 1 1 0 Lipopolysaccharide export system permease LptF/LptG Epimerase PF01370.21 EGC39777.1 - 1.3e-11 44.5 0.2 1.3e-10 41.2 0.2 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family GDP_Man_Dehyd PF16363.5 EGC39777.1 - 1.9e-05 24.2 0.1 0.00082 18.9 0.0 2.3 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NmrA PF05368.13 EGC39777.1 - 0.00013 21.6 0.2 0.0014 18.2 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.19 EGC39777.1 - 0.0006 18.9 1.1 0.16 10.9 0.1 2.4 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family adh_short PF00106.25 EGC39777.1 - 0.0018 17.7 0.0 0.0032 16.9 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.6 EGC39777.1 - 0.015 15.2 0.0 0.021 14.7 0.0 1.3 1 0 0 1 1 1 0 NAD(P)H-binding NAD_binding_2 PF03446.15 EGC39777.1 - 0.027 14.6 0.0 0.048 13.8 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DUF4225 PF13988.6 EGC39777.1 - 0.06 12.9 2.0 0.12 11.9 1.0 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4225) ApbA PF02558.16 EGC39777.1 - 0.074 12.7 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Pyr_redox PF00070.27 EGC39777.1 - 0.088 13.4 0.2 0.2 12.2 0.2 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.18 EGC39777.1 - 0.1 12.5 0.0 0.21 11.4 0.0 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Clathrin_propel PF01394.20 EGC39777.1 - 0.14 12.5 0.5 17 6.0 0.0 2.6 1 1 1 2 2 2 0 Clathrin propeller repeat Exonuc_VII_L PF02601.15 EGC39778.1 - 3 7.3 17.1 1.9 8.0 12.3 2.3 2 0 0 2 2 2 0 Exonuclease VII, large subunit CdiA_C_tRNase PF18664.1 EGC39778.1 - 4 7.6 7.8 4.2 7.6 0.1 2.7 2 0 0 2 2 2 0 CdiA C-terminal tRNase domain Phage_Gp111 PF07410.11 EGC39778.1 - 6.3 7.3 6.0 46 4.5 0.6 2.7 1 1 1 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein DUF5504 PF17608.2 EGC39780.1 - 0.043 13.9 0.6 0.11 12.6 0.6 1.6 1 0 0 1 1 1 0 Family of unknown function (DUF5504) AIG1 PF04548.16 EGC39781.1 - 6.1e-22 78.0 0.0 1.1e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.23 EGC39781.1 - 2.6e-10 40.4 0.0 5.1e-10 39.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC39781.1 - 4.1e-05 23.5 0.1 7.9e-05 22.6 0.1 1.4 1 0 0 1 1 1 1 RsgA GTPase Dynamin_N PF00350.23 EGC39781.1 - 0.00086 19.4 4.0 0.022 14.8 0.1 3.1 2 1 1 3 3 3 1 Dynamin family AAA_16 PF13191.6 EGC39781.1 - 0.0013 19.1 0.0 0.0036 17.7 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Septin PF00735.18 EGC39781.1 - 0.0029 16.9 0.2 0.009 15.3 0.2 1.8 1 1 0 1 1 1 1 Septin G-alpha PF00503.20 EGC39781.1 - 0.0088 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 G-protein alpha subunit AAA_7 PF12775.7 EGC39781.1 - 0.0092 15.5 0.0 0.021 14.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing dynein motor region FtsK_SpoIIIE PF01580.18 EGC39781.1 - 0.012 15.0 0.5 0.048 13.0 0.0 2.2 4 0 0 4 4 4 0 FtsK/SpoIIIE family T2SSE PF00437.20 EGC39781.1 - 0.027 13.5 0.0 0.049 12.7 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein Gtr1_RagA PF04670.12 EGC39781.1 - 0.028 13.8 0.1 0.048 13.0 0.1 1.4 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF815 PF05673.13 EGC39781.1 - 0.033 13.3 0.0 0.06 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.27 EGC39781.1 - 0.04 14.4 0.0 0.077 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter Ndc1_Nup PF09531.10 EGC39781.1 - 0.048 12.4 0.7 0.056 12.1 0.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FeoB_N PF02421.18 EGC39781.1 - 0.073 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.6 EGC39781.1 - 0.082 13.5 0.1 4.5 7.8 0.1 2.9 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.17 EGC39781.1 - 0.084 12.6 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein ORC6 PF05460.13 EGC39781.1 - 0.55 9.5 9.1 0.79 8.9 9.1 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) RAP1 PF07218.11 EGC39781.1 - 1.4 7.1 7.5 1.7 6.8 7.5 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) Peptidase_U4 PF03419.13 EGC39782.1 - 0.0032 16.8 1.0 0.0037 16.6 1.0 1.1 1 0 0 1 1 1 1 Sporulation factor SpoIIGA Prp19 PF08606.11 EGC39783.1 - 2e-32 111.0 2.0 5.6e-32 109.5 2.0 1.8 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.32 EGC39783.1 - 9.3e-16 57.9 8.1 0.0016 19.2 0.0 6.1 7 0 0 7 7 7 4 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC39783.1 - 1.2e-07 31.9 0.0 0.11 12.8 0.0 4.4 1 1 4 5 5 5 3 Anaphase-promoting complex subunit 4 WD40 domain WD40_like PF17005.5 EGC39783.1 - 8.3e-05 22.0 3.3 0.11 11.8 0.2 2.4 2 0 0 2 2 2 2 WD40-like domain zf-Nse PF11789.8 EGC39783.1 - 0.028 14.2 0.0 0.057 13.3 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit BRK PF07533.16 EGC39783.1 - 0.16 11.6 0.0 2.1 8.0 0.0 2.6 3 0 0 3 3 3 0 BRK domain 2-Hacid_dh_C PF02826.19 EGC39784.1 - 2e-62 209.7 0.0 5e-62 208.4 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC39784.1 - 3.6e-29 101.1 0.1 4.1e-29 100.9 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC39784.1 - 9.4e-08 32.4 0.4 5.7e-07 29.8 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGC39784.1 - 0.00012 21.7 0.2 0.00067 19.3 0.0 2.0 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain F420_oxidored PF03807.17 EGC39784.1 - 0.0023 18.5 0.0 0.086 13.4 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CPSF73-100_C PF11718.8 EGC39784.1 - 0.0042 16.7 0.0 0.0062 16.1 0.0 1.3 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Shikimate_DH PF01488.20 EGC39784.1 - 0.0089 16.1 0.1 0.048 13.7 0.0 2.2 2 1 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase Sacchrp_dh_NADP PF03435.18 EGC39784.1 - 0.012 15.8 0.3 0.27 11.5 0.1 3.0 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain Gp_dh_N PF00044.24 EGC39784.1 - 0.079 13.3 0.1 0.31 11.4 0.0 2.1 2 0 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Peroxin-22 PF12827.7 EGC39784.1 - 0.083 12.8 0.1 0.27 11.2 0.0 1.9 2 0 0 2 2 2 0 Peroxisomal biogenesis protein family GFO_IDH_MocA PF01408.22 EGC39784.1 - 0.14 13.0 0.0 0.43 11.4 0.0 1.9 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.19 EGC39785.1 - 2.5e-62 209.4 0.0 4.1e-62 208.7 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC39785.1 - 2e-28 98.7 0.1 2.3e-28 98.5 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC39785.1 - 1.5e-06 28.5 0.1 3.8e-06 27.2 0.0 1.7 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGC39785.1 - 0.00048 19.8 0.1 0.0013 18.4 0.0 1.7 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain CPSF73-100_C PF11718.8 EGC39785.1 - 0.0044 16.6 0.0 0.0071 15.9 0.0 1.4 1 0 0 1 1 1 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Shikimate_DH PF01488.20 EGC39785.1 - 0.027 14.5 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase F420_oxidored PF03807.17 EGC39785.1 - 0.034 14.7 0.0 0.24 12.0 0.0 2.2 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.22 EGC39785.1 - 0.054 14.3 0.0 0.2 12.5 0.0 2.0 2 1 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold Sacchrp_dh_NADP PF03435.18 EGC39785.1 - 0.059 13.6 0.1 0.59 10.4 0.1 2.5 1 1 0 1 1 1 0 Saccharopine dehydrogenase NADP binding domain F5_F8_type_C PF00754.25 EGC39787.1 - 2.4e-25 89.1 1.7 3.2e-25 88.7 1.1 1.5 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC39787.1 - 4.4e-18 65.2 0.5 1.3e-17 63.7 0.5 1.9 1 0 0 1 1 1 1 H-type lectin domain BLOC1S3 PF15753.5 EGC39788.1 - 3.5e-06 27.3 23.0 0.0024 18.1 23.0 2.9 1 1 0 1 1 1 1 Biogenesis of lysosome-related organelles complex 1 subunit 3 ABC2_membrane_3 PF12698.7 EGC39788.1 - 0.21 10.6 3.4 0.27 10.3 3.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Mucin PF01456.17 EGC39788.1 - 0.45 10.5 12.2 0.65 10.0 12.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.13 EGC39788.1 - 2.9 6.2 12.9 4.4 5.5 12.9 1.2 1 0 0 1 1 1 0 Menin Orf78 PF06024.12 EGC39788.1 - 4.4 7.7 13.6 38 4.7 0.1 2.6 2 1 0 2 2 2 0 Orf78 (ac78) FNIP PF05725.12 EGC39789.1 - 0 1130.6 174.9 9.6e-16 57.7 0.1 26.2 11 4 20 33 33 33 33 FNIP Repeat Phage_min_tail PF05939.13 EGC39789.1 - 6.1e-13 49.1 1.9 3.4 8.1 0.0 15.4 8 6 11 21 21 21 2 Phage minor tail protein COMM_domain PF07258.14 EGC39791.1 - 6.7e-16 58.2 7.3 1.2e-15 57.4 6.4 1.9 2 0 0 2 2 2 1 COMM domain COMMD1_N PF17221.3 EGC39791.1 - 1.2e-13 51.2 4.1 3.6e-12 46.5 0.5 2.2 2 0 0 2 2 2 2 COMMD1 N-terminal domain BioW PF03744.13 EGC39791.1 - 0.073 12.6 2.8 0.099 12.2 2.8 1.2 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase TbpB_A PF17484.2 EGC39791.1 - 0.4 11.4 2.9 0.83 10.4 2.9 1.5 1 0 0 1 1 1 0 N-Lobe handle Tf-binding protein B HAD_2 PF13419.6 EGC39791.1 - 1.4 9.0 10.1 0.52 10.4 7.6 1.6 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase MARVEL PF01284.23 EGC39792.1 - 0.0032 17.5 0.7 0.0032 17.5 0.7 2.7 1 1 1 2 2 2 1 Membrane-associating domain Deltameth_res PF16020.5 EGC39792.1 - 0.41 10.5 0.1 0.41 10.5 0.1 3.3 3 0 0 3 3 3 0 Deltamethrin resistance 2-Hacid_dh_C PF02826.19 EGC39793.1 - 3.2e-57 192.8 0.0 5.7e-57 191.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.30 EGC39793.1 - 1e-19 70.5 0.0 1.2e-19 70.3 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.15 EGC39793.1 - 0.00024 21.3 0.0 0.0004 20.6 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.12 EGC39793.1 - 0.00038 20.1 0.0 0.00066 19.3 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, NADPH-binding domain Sacchrp_dh_NADP PF03435.18 EGC39793.1 - 0.023 14.9 1.4 1.6 9.0 0.5 3.1 2 1 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain F420_oxidored PF03807.17 EGC39793.1 - 0.028 15.0 0.0 0.06 13.9 0.0 1.6 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent NAD_binding_7 PF13241.6 EGC39793.1 - 0.072 13.5 0.0 0.15 12.5 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ThiF PF00899.21 EGC39793.1 - 0.087 12.2 0.1 0.76 9.1 0.0 2.3 2 0 0 2 2 2 0 ThiF family Shikimate_DH PF01488.20 EGC39793.1 - 0.093 12.8 0.0 0.33 11.0 0.0 1.9 2 1 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase RhoGEF PF00621.20 EGC39794.1 - 8.3e-75 251.0 26.1 1.9e-45 155.4 7.1 3.5 3 1 0 3 3 3 2 RhoGEF domain RhoGAP PF00620.27 EGC39794.1 - 2.8e-44 150.6 5.8 2.8e-44 150.6 0.1 3.1 3 0 0 3 3 3 1 RhoGAP domain SH3_1 PF00018.28 EGC39794.1 - 5e-12 45.2 0.1 1e-11 44.2 0.1 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.6 EGC39794.1 - 1.5e-11 44.0 0.0 2.7e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.17 EGC39794.1 - 7e-08 32.0 0.1 1.8e-07 30.7 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain PH PF00169.29 EGC39794.1 - 4.5e-07 30.3 0.6 1.5e-06 28.7 0.0 2.2 2 0 0 2 2 2 1 PH domain PH_6 PF15406.6 EGC39794.1 - 0.013 15.8 0.1 0.037 14.3 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 EGC39794.1 - 0.054 13.5 0.6 0.18 11.8 0.1 2.1 2 0 0 2 2 2 0 PH domain PH_13 PF16652.5 EGC39794.1 - 0.36 10.6 8.4 1 9.2 1.7 3.2 2 1 0 2 2 2 0 Pleckstrin homology domain DMPK_coil PF08826.10 EGC39795.1 - 0.028 14.5 2.9 0.028 14.5 2.9 3.6 3 0 0 3 3 3 0 DMPK coiled coil domain like DUF2536 PF10750.9 EGC39795.1 - 0.6 10.0 6.3 0.37 10.7 2.6 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) Ank_4 PF13637.6 EGC39798.1 - 2.3e-18 66.3 0.1 8.1e-10 39.1 0.0 3.6 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_2 PF12796.7 EGC39798.1 - 1.9e-14 54.0 0.0 4.5e-14 52.8 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.6 EGC39798.1 - 5.7e-14 52.0 0.0 8.9e-11 41.8 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC39798.1 - 1.9e-12 47.0 0.0 2.8e-07 30.7 0.0 3.2 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.6 EGC39798.1 - 2e-10 40.0 0.0 0.00014 22.0 0.0 3.9 3 0 0 3 3 3 3 Ankyrin repeat RA PF00788.23 EGC39798.1 - 2.4e-06 28.1 0.4 6.1e-06 26.8 0.4 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain RseA_C PF03873.13 EGC39798.1 - 0.13 12.5 0.2 0.26 11.5 0.2 1.5 1 0 0 1 1 1 0 Anti sigma-E protein RseA, C-terminal domain Pyridoxal_deC PF00282.19 EGC39799.1 - 3.3e-17 62.3 0.0 6.5e-17 61.3 0.0 1.5 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.19 EGC39799.1 - 8.3e-09 34.9 0.0 2e-08 33.6 0.0 1.6 1 0 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.21 EGC39799.1 - 2.8e-06 26.8 0.0 4.8e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.17 EGC39799.1 - 6.6e-05 22.4 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SepSecS PF05889.13 EGC39799.1 - 0.0025 16.6 0.0 0.0064 15.2 0.0 1.6 2 0 0 2 2 2 1 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS Cys_Met_Meta_PP PF01053.20 EGC39799.1 - 0.051 12.1 0.0 0.082 11.4 0.0 1.3 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme HTH_16 PF12645.7 EGC39799.1 - 0.067 13.2 0.0 0.23 11.5 0.0 1.9 1 0 0 1 1 1 0 Helix-turn-helix domain PsbU PF06514.11 EGC39799.1 - 0.11 12.5 1.4 37 4.4 0.0 3.8 3 1 1 4 4 4 0 Photosystem II 12 kDa extrinsic protein (PsbU) PIP5K PF01504.18 EGC39800.1 - 7.2e-74 248.4 12.0 7.2e-74 248.4 12.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.29 EGC39800.1 - 2.5e-12 47.2 1.3 8.8e-12 45.5 0.4 2.5 2 0 0 2 2 2 1 PH domain PH_11 PF15413.6 EGC39800.1 - 0.00044 20.6 0.3 0.00044 20.6 0.3 3.7 3 2 0 3 3 3 1 Pleckstrin homology domain Abhydrolase_3 PF07859.13 EGC39801.1 - 1.8e-48 165.2 0.0 2.2e-48 164.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Say1_Mug180 PF10340.9 EGC39801.1 - 0.00075 18.5 0.0 0.0015 17.5 0.0 1.4 1 1 0 1 1 1 1 Steryl acetyl hydrolase DLH PF01738.18 EGC39801.1 - 0.04 13.5 0.0 0.04 13.5 0.0 1.5 2 0 0 2 2 2 0 Dienelactone hydrolase family Peptidase_S9 PF00326.21 EGC39801.1 - 0.059 12.8 0.0 0.27 10.7 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.28 EGC39801.1 - 0.085 11.7 0.0 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC39802.1 - 4.7e-24 85.4 0.0 6.5e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold GST_C PF00043.25 EGC39802.1 - 0.056 13.7 0.0 0.095 12.9 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COesterase PF00135.28 EGC39802.1 - 0.16 10.8 0.0 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LIM_bind PF01803.16 EGC39803.1 - 4e-32 111.7 15.4 6.7e-28 97.8 11.9 4.7 3 2 0 3 3 3 2 LIM-domain binding protein Pkinase PF00069.25 EGC39804.1 - 1.2e-64 218.3 0.0 1.4e-64 218.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39804.1 - 4.7e-18 65.4 0.0 6.8e-18 64.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC39804.1 - 2.1e-07 31.1 0.0 6.4e-07 29.5 0.1 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC39804.1 - 0.0059 15.4 0.1 0.014 14.2 0.0 1.6 2 0 0 2 2 2 1 Fungal protein kinase Choline_kinase PF01633.20 EGC39804.1 - 0.0089 15.6 0.2 0.02 14.5 0.2 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.14 EGC39804.1 - 0.06 12.7 0.2 0.12 11.7 0.2 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PMC2NT PF08066.12 EGC39805.1 - 3.3 8.5 11.3 0.13 13.0 3.3 3.0 3 0 0 3 3 3 0 PMC2NT (NUC016) domain SPX PF03105.19 EGC39805.1 - 5.2 6.9 37.5 0.4 10.5 10.2 2.3 2 0 0 2 2 2 0 SPX domain HCO3_cotransp PF00955.21 EGC39806.1 - 3.7 6.3 5.3 2.3 6.9 2.2 2.2 2 0 0 2 2 2 0 HCO3- transporter family DEAD PF00270.29 EGC39807.1 - 6e-42 143.4 0.1 3.4e-41 140.9 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC39807.1 - 2.6e-23 82.5 0.2 2.6e-23 82.5 0.2 2.8 4 0 0 4 4 4 1 Helicase conserved C-terminal domain CMS1 PF14617.6 EGC39807.1 - 0.00087 18.7 0.0 0.00087 18.7 0.0 2.8 4 0 0 4 4 4 1 U3-containing 90S pre-ribosomal complex subunit F-box-like PF12937.7 EGC39808.1 - 0.079 12.9 0.0 1.3 9.0 0.0 2.6 2 0 0 2 2 2 0 F-box-like F-box_5 PF18511.1 EGC39808.1 - 0.19 11.3 0.1 0.44 10.2 0.1 1.5 1 0 0 1 1 1 0 F-box Peptidase_C1 PF00112.23 EGC39809.1 - 3.3e-58 197.3 2.4 3.3e-58 197.3 2.4 2.3 2 0 0 2 2 2 1 Papain family cysteine protease CBM49 PF09478.10 EGC39809.1 - 7e-39 132.0 15.6 7.3e-20 71.1 2.0 3.0 3 0 0 3 3 3 2 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.12 EGC39809.1 - 3.3e-12 46.7 8.9 1.3e-11 44.7 8.9 2.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) CBM_2 PF00553.19 EGC39809.1 - 1.5e-06 28.4 5.4 0.019 15.3 0.8 2.8 2 0 0 2 2 2 2 Cellulose binding domain TonB_2 PF13103.6 EGC39809.1 - 0.0018 18.5 0.5 3.9 7.8 0.0 2.8 3 0 0 3 3 3 2 TonB C terminal Vps4_C PF09336.10 EGC39809.1 - 0.081 12.9 0.1 21 5.2 0.0 2.5 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF4219 PF13961.6 EGC39809.1 - 0.12 12.0 3.2 5.2 6.8 0.2 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) RHIM PF12721.7 EGC39809.1 - 0.48 10.9 3.8 20 5.7 0.3 2.7 2 0 0 2 2 2 0 RIP homotypic interaction motif Mt_ATP-synt_D PF05873.12 EGC39809.1 - 4.9 7.0 14.6 1 9.2 5.8 3.1 3 0 0 3 3 3 0 ATP synthase D chain, mitochondrial (ATP5H) FAM176 PF14851.6 EGC39809.1 - 8.4 6.1 7.3 26 4.5 7.3 1.8 1 0 0 1 1 1 0 FAM176 family Peptidase_C1 PF00112.23 EGC39810.1 - 3.9e-50 171.0 2.9 6.8e-40 137.5 1.4 3.3 2 1 1 3 3 3 2 Papain family cysteine protease CBM49 PF09478.10 EGC39810.1 - 4.4e-20 71.8 1.9 1.3e-19 70.3 1.9 1.8 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.12 EGC39810.1 - 1.2e-11 44.9 9.0 1.2e-11 44.9 9.0 2.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.15 EGC39810.1 - 1.9e-05 23.6 6.3 0.00051 18.9 0.2 3.1 3 0 0 3 3 3 2 Peptidase C1-like family CBM_2 PF00553.19 EGC39810.1 - 0.0044 17.3 0.2 0.012 15.9 0.2 1.7 1 0 0 1 1 1 1 Cellulose binding domain GPR15L PF15854.5 EGC39810.1 - 0.21 11.9 0.2 0.93 9.8 0.0 2.2 2 0 0 2 2 2 0 G-protein coupled receptor ligand 15 FAM176 PF14851.6 EGC39810.1 - 0.24 11.0 4.7 0.37 10.5 3.1 2.2 2 0 0 2 2 2 0 FAM176 family NmrA PF05368.13 EGC39811.1 - 3.1e-57 193.8 0.1 3.7e-57 193.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC39811.1 - 1.3e-07 31.7 0.0 1.9e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 NAD(P)H-binding LytR_C PF13399.6 EGC39811.1 - 0.04 14.9 0.1 0.11 13.5 0.1 1.8 1 0 0 1 1 1 0 LytR cell envelope-related transcriptional attenuator PBS_linker_poly PF00427.21 EGC39811.1 - 0.085 12.9 0.6 0.38 10.8 0.1 2.3 3 0 0 3 3 3 0 Phycobilisome Linker polypeptide Glyco_hydro_47 PF01532.20 EGC39812.1 - 2.4e-106 356.4 0.0 4.1e-106 355.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Atg29_N PF18388.1 EGC39813.1 - 3.6e-11 42.7 0.6 1.2e-10 41.0 0.6 2.0 1 0 0 1 1 1 1 Atg29 N-terminal domain TFIIA PF03153.13 EGC39813.1 - 0.0056 16.7 52.7 0.0079 16.2 52.7 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit DUF4776 PF16003.5 EGC39813.1 - 0.28 10.1 27.1 0.37 9.7 27.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4776) DUF2072 PF09845.9 EGC39813.1 - 1.1 9.6 18.3 0.045 14.0 10.4 2.2 2 0 0 2 2 2 0 Zn-ribbon containing protein DUF4175 PF13779.6 EGC39813.1 - 2.1 6.1 40.9 2.6 5.9 40.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PepSY_TM PF03929.16 EGC39813.1 - 5.5 6.6 8.2 7.7 6.1 8.2 1.2 1 0 0 1 1 1 0 PepSY-associated TM region SprA-related PF12118.8 EGC39813.1 - 7.3 5.6 38.7 11 5.0 38.7 1.4 1 0 0 1 1 1 0 SprA-related family SQS_PSY PF00494.19 EGC39814.1 - 4.1e-40 137.9 0.0 5e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase CH PF00307.31 EGC39815.1 - 4.9e-37 126.4 10.4 2e-18 66.6 1.0 4.1 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.8 EGC39815.1 - 0.064 13.1 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 CAMSAP CH domain Kelch_1 PF01344.25 EGC39816.1 - 4.7e-40 134.9 6.0 1.5e-09 37.3 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.6 EGC39816.1 - 1.1e-37 127.0 14.5 3e-08 33.7 0.1 6.7 5 2 2 7 7 7 6 Kelch motif Kelch_4 PF13418.6 EGC39816.1 - 1e-34 118.3 13.4 6.5e-10 38.9 0.1 6.4 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_5 PF13854.6 EGC39816.1 - 8.3e-30 102.3 3.9 0.00013 21.8 0.0 6.8 7 0 0 7 7 7 5 Kelch motif Kelch_3 PF13415.6 EGC39816.1 - 2.2e-29 101.1 3.6 6.8e-08 32.6 0.0 7.6 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_2 PF07646.15 EGC39816.1 - 1.7e-28 97.5 11.1 1.7e-08 34.1 0.2 6.9 6 1 0 6 6 6 5 Kelch motif F-box-like PF12937.7 EGC39816.1 - 7.3e-07 29.0 0.1 1.9e-06 27.6 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.33 EGC39816.1 - 0.00021 21.1 0.0 0.00057 19.7 0.0 1.7 1 0 0 1 1 1 1 F-box domain CFIA_Pcf11 PF11526.8 EGC39816.1 - 0.0089 16.5 2.0 0.0089 16.5 2.0 6.0 3 1 0 4 4 4 2 Subunit of cleavage factor IA Pcf11 F-box_4 PF15966.5 EGC39816.1 - 0.034 14.0 0.0 0.17 11.7 0.0 2.1 2 0 0 2 2 2 0 F-box Cnd2 PF05786.14 EGC39817.1 - 8.4e-127 424.9 58.2 8.4e-127 424.9 58.2 2.0 1 1 1 2 2 2 1 Condensin complex subunit 2 CNDH2_N PF06278.11 EGC39817.1 - 0.0018 18.5 0.1 0.0018 18.5 0.1 5.1 6 2 0 6 6 6 1 Condensin II complex subunit CAP-H2 or CNDH2, N-terminal Dicty_CAR PF05462.11 EGC39818.1 - 8.2e-12 44.9 9.9 8.2e-12 44.9 9.9 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Frizzled PF01534.17 EGC39818.1 - 0.00012 21.2 15.3 0.00018 20.7 15.3 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF805 PF05656.14 EGC39818.1 - 1.2 9.6 7.4 1.2 9.6 1.6 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF805) DUF373 PF04123.13 EGC39818.1 - 4.5 6.6 7.0 0.77 9.1 3.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF373) ABC2_membrane_2 PF12679.7 EGC39819.1 - 0.032 13.5 6.4 0.13 11.5 5.5 2.3 2 1 1 3 3 3 0 ABC-2 family transporter protein DUF4781 PF16013.5 EGC39819.1 - 0.2 10.4 0.3 0.31 9.8 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4781) DUF418 PF04235.12 EGC39819.1 - 0.44 10.5 7.2 0.085 12.8 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF418) Smr PF01713.21 EGC39820.1 - 2.4e-08 34.2 0.0 5.2e-08 33.1 0.0 1.5 2 0 0 2 2 2 1 Smr domain CCB1 PF12046.8 EGC39820.1 - 0.16 11.3 0.9 7.1 6.0 0.0 2.8 1 1 2 3 3 3 0 Cofactor assembly of complex C subunit B DUSP PF06337.12 EGC39821.1 - 4.5e-14 52.8 0.9 4.5e-14 52.8 0.9 5.7 4 3 0 4 4 4 1 DUSP domain zinc-ribbons_6 PF07191.12 EGC39821.1 - 4.6 7.3 9.6 0.55 10.2 4.4 2.0 1 1 1 2 2 2 0 zinc-ribbons RhoGEF PF00621.20 EGC39822.1 - 1e-50 172.5 7.9 3.3e-50 170.9 3.7 2.2 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.21 EGC39822.1 - 1.8e-20 72.8 11.3 4.1e-20 71.7 11.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.29 EGC39822.1 - 4.1e-09 36.9 0.9 1.1e-08 35.5 0.9 1.8 1 0 0 1 1 1 1 PH domain PH_13 PF16652.5 EGC39822.1 - 0.01 15.7 2.6 0.016 15.0 0.8 2.3 2 1 0 2 2 2 0 Pleckstrin homology domain IQ_SEC7_PH PF16453.5 EGC39822.1 - 0.11 12.5 5.8 0.17 11.8 0.2 3.0 3 0 0 3 3 3 0 PH domain RecR PF02132.15 EGC39822.1 - 2 8.1 8.9 6 6.5 0.1 2.8 2 0 0 2 2 2 0 RecR protein DZR PF12773.7 EGC39822.1 - 4.9 7.3 10.2 9.9e+02 -0.1 11.0 2.5 1 1 0 1 1 1 0 Double zinc ribbon zf-B_box PF00643.24 EGC39822.1 - 9.4 6.5 11.3 2.7 8.2 7.3 2.1 2 0 0 2 2 2 0 B-box zinc finger Cullin PF00888.22 EGC39823.1 - 3.1e-195 650.4 16.6 3.1e-195 650.4 16.6 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.9 EGC39823.1 - 9.3e-27 92.9 5.9 9.3e-27 92.9 5.9 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain Phage_TAC_12 PF12363.8 EGC39823.1 - 0.015 15.7 0.3 0.33 11.4 0.0 3.0 2 0 0 2 2 2 0 Phage tail assembly chaperone protein, TAC MukF_M PF17192.4 EGC39823.1 - 0.067 12.9 1.0 0.52 10.0 0.2 2.7 2 0 0 2 2 2 0 MukF middle domain IL28A PF15177.6 EGC39823.1 - 0.19 11.6 3.2 0.29 11.0 0.1 2.7 3 0 0 3 3 3 0 Interleukin-28A NAGLU PF05089.12 EGC39824.1 - 9.3e-137 455.4 10.4 1.3e-136 454.9 10.4 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.7 EGC39824.1 - 6e-70 235.8 0.9 8e-70 235.4 0.9 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.7 EGC39824.1 - 4.4e-14 52.0 0.2 9.3e-14 51.0 0.2 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Ribosomal_L6e PF01159.19 EGC39824.1 - 0.15 12.6 0.2 0.29 11.7 0.2 1.4 1 0 0 1 1 1 0 Ribosomal protein L6e SAGA-Tad1 PF12767.7 EGC39825.1 - 2e-40 139.0 4.0 2e-40 139.0 4.0 2.2 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit Nup54_57_C PF18570.1 EGC39825.1 - 0.044 13.4 4.0 0.52 9.9 0.1 2.9 3 0 0 3 3 3 0 NUP57/Nup54 C-terminal domain Romo1 PF10247.9 EGC39826.1 - 0.016 15.6 0.0 0.038 14.4 0.0 1.7 1 0 0 1 1 1 0 Reactive mitochondrial oxygen species modulator 1 VIT PF08487.10 EGC39827.1 - 7.9e-28 96.9 0.4 7.9e-28 96.9 0.4 2.2 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.6 EGC39827.1 - 3.3e-26 92.1 0.0 5.7e-26 91.3 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.28 EGC39827.1 - 1.9e-12 47.8 0.0 4.8e-12 46.5 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.6 EGC39827.1 - 4.1e-10 40.3 0.0 2.3e-09 37.8 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain vWA-TerF-like PF10138.9 EGC39827.1 - 0.00053 20.1 0.0 0.0013 18.9 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VIT_2 PF13757.6 EGC39827.1 - 0.0052 16.6 0.1 0.016 15.1 0.0 2.0 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain VWA_CoxE PF05762.14 EGC39827.1 - 0.0082 15.5 0.0 0.19 11.1 0.0 2.2 2 0 0 2 2 2 1 VWA domain containing CoxE-like protein Rubella_Capsid PF05750.11 EGC39827.1 - 1.3 8.6 2.9 2.1 7.9 2.9 1.2 1 0 0 1 1 1 0 Rubella capsid protein Laminin_EGF PF00053.24 EGC39828.1 - 0.0022 18.1 34.2 0.36 11.0 9.0 3.8 2 1 1 3 3 3 3 Laminin EGF domain EGF_2 PF07974.13 EGC39828.1 - 0.003 17.9 47.9 0.47 10.9 8.8 4.0 3 0 0 3 3 3 3 EGF-like domain DUF2723 PF11028.8 EGC39829.1 - 7.1e-38 130.2 12.4 1.5e-37 129.1 12.4 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) vATP-synt_E PF01991.18 EGC39830.1 - 8.8e-73 244.0 7.1 1e-72 243.8 7.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit UPF0139 PF03669.13 EGC39831.1 - 4.8e-28 96.9 0.4 5.1e-28 96.8 0.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) MadM PF03818.13 EGC39831.1 - 0.027 14.4 2.3 0.042 13.7 1.6 1.7 1 1 1 2 2 2 0 Malonate/sodium symporter MadM subunit Pyridoxal_deC PF00282.19 EGC39832.1 - 2.4e-23 82.5 0.0 2e-14 53.1 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain RLL PF10036.9 EGC39833.1 - 2.1e-59 201.4 13.9 2.9e-59 201.0 13.9 1.2 1 0 0 1 1 1 1 RNA transcription, translation and transport factor protein Csm1 PF12539.8 EGC39833.1 - 0.11 13.1 1.4 0.2 12.3 0.6 2.1 2 1 0 2 2 2 0 Chromosome segregation protein Csm1/Pcs1 Mrr_cat_2 PF13156.6 EGC39833.1 - 1.6 8.6 5.4 0.13 12.2 0.4 1.8 2 1 0 2 2 2 0 Restriction endonuclease DUF1697 PF08002.11 EGC39834.1 - 2.9e-19 69.9 0.1 4.1e-19 69.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) DUF836 PF05768.14 EGC39834.1 - 0.017 15.5 0.7 0.6 10.6 0.1 2.4 1 1 1 2 2 2 0 Glutaredoxin-like domain (DUF836) DUF3887 PF13026.6 EGC39834.1 - 0.051 14.4 0.2 0.14 13.0 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Peptidase_C23 PF05379.11 EGC39834.1 - 0.12 12.5 0.1 0.22 11.7 0.1 1.5 1 1 0 1 1 1 0 Carlavirus endopeptidase DUF3924 PF13062.6 EGC39835.1 - 0.14 12.1 2.0 0.43 10.6 2.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3924) FNIP PF05725.12 EGC39836.1 - 2e-59 197.5 59.9 8.1e-14 51.5 1.5 8.6 4 2 2 8 8 8 8 FNIP Repeat DUF1769 PF08588.10 EGC39836.1 - 0.011 15.9 2.7 22 5.4 0.1 4.6 3 1 1 4 4 4 0 Protein of unknown function (DUF1769) LRR_5 PF13306.6 EGC39836.1 - 0.015 15.3 23.4 0.16 12.0 0.6 4.5 3 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Peptidase_S24 PF00717.23 EGC39836.1 - 0.019 14.9 0.1 0.046 13.7 0.1 1.7 1 0 0 1 1 1 0 Peptidase S24-like Tecti-min-caps PF09300.10 EGC39836.1 - 0.37 10.9 3.1 71 3.6 0.0 4.6 4 1 1 5 5 5 0 Tectiviridae, minor capsid Acetyltransf_2 PF00797.17 EGC39837.1 - 6.8e-26 91.5 0.1 8.4e-26 91.2 0.1 1.0 1 0 0 1 1 1 1 N-acetyltransferase Lyase_aromatic PF00221.19 EGC39838.1 - 5.9e-141 470.3 0.0 6.8e-141 470.1 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CAP18_C PF12153.8 EGC39838.1 - 0.036 13.9 2.6 0.071 13.0 2.6 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) NmrA PF05368.13 EGC39839.1 - 2.3e-22 79.7 0.1 2.8e-22 79.4 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.6 EGC39839.1 - 4.4e-14 52.8 0.0 7.9e-14 52.0 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H-binding Epimerase PF01370.21 EGC39839.1 - 7.8e-06 25.5 0.0 3.5e-05 23.4 0.0 2.1 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.19 EGC39839.1 - 7.9e-05 21.8 0.1 0.00018 20.7 0.1 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family GDP_Man_Dehyd PF16363.5 EGC39839.1 - 0.00045 19.7 0.1 0.0013 18.2 0.0 1.8 2 0 0 2 2 2 1 GDP-mannose 4,6 dehydratase NAD_binding_4 PF07993.12 EGC39839.1 - 0.0035 16.6 0.0 0.0051 16.0 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein TrkA_N PF02254.18 EGC39839.1 - 0.0041 17.4 0.0 0.0077 16.5 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain YflT PF11181.8 EGC39839.1 - 0.059 13.9 0.6 0.25 11.9 0.1 2.1 2 0 0 2 2 2 0 Heat induced stress protein YflT Sacchrp_dh_NADP PF03435.18 EGC39839.1 - 0.059 13.6 0.0 0.48 10.7 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase NADP binding domain ERCC3_RAD25_C PF16203.5 EGC39840.1 - 2e-118 394.1 0.1 3.4e-118 393.3 0.1 1.3 1 0 0 1 1 1 1 ERCC3/RAD25/XPB C-terminal helicase Helicase_C_3 PF13625.6 EGC39840.1 - 6.5e-37 126.5 0.0 1.2e-36 125.7 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.15 EGC39840.1 - 4.7e-12 46.2 0.5 1.1e-11 45.1 0.0 1.9 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.31 EGC39840.1 - 7.1e-11 42.4 0.1 2.7e-10 40.6 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.23 EGC39840.1 - 1.2e-06 27.5 0.0 2e-05 23.5 0.0 2.0 1 1 1 2 2 2 1 SNF2 family N-terminal domain RasGEF PF00617.19 EGC39841.1 - 6.6e-51 173.0 4.6 6.6e-51 173.0 4.6 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.20 EGC39841.1 - 6.6e-06 26.3 3.2 6.6e-06 26.3 3.2 5.6 4 2 1 5 5 5 1 RasGEF N-terminal motif Pkinase PF00069.25 EGC39842.1 - 1e-49 169.3 0.0 2e-49 168.3 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39842.1 - 5.9e-38 130.6 0.0 7.8e-38 130.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.23 EGC39842.1 - 0.0057 16.6 0.0 0.18 11.7 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Pkinase_fungal PF17667.1 EGC39842.1 - 0.021 13.6 1.7 0.03 13.1 0.0 1.8 2 0 0 2 2 2 0 Fungal protein kinase Haspin_kinase PF12330.8 EGC39842.1 - 0.08 11.9 0.0 0.08 11.9 0.0 2.3 2 0 0 2 2 2 0 Haspin like kinase domain AAA_12 PF13087.6 EGC39843.1 - 3.3e-41 141.1 0.3 3.3e-41 141.1 0.3 2.6 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.6 EGC39843.1 - 1.3e-23 84.1 2.1 1.3e-23 84.1 2.1 4.2 2 2 1 3 3 3 1 AAA domain AAA_19 PF13245.6 EGC39843.1 - 1.1e-07 32.2 0.0 1.8e-06 28.4 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC39843.1 - 3.2e-07 30.3 0.0 0.00096 18.9 0.0 2.3 2 0 0 2 2 2 2 AAA domain SAM_1 PF00536.30 EGC39843.1 - 3.7e-07 30.5 1.3 1.4e-06 28.6 0.1 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.17 EGC39843.1 - 9.8e-05 22.4 0.1 0.00027 21.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_22 PF13401.6 EGC39843.1 - 0.00056 20.2 0.2 0.029 14.6 0.0 3.3 3 0 0 3 3 3 1 AAA domain TniB PF05621.11 EGC39843.1 - 0.024 14.1 0.0 0.98 8.8 0.0 2.6 2 0 0 2 2 2 0 Bacterial TniB protein AAA_16 PF13191.6 EGC39843.1 - 0.042 14.2 0.0 0.098 13.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.6 EGC39843.1 - 0.22 11.0 0.0 0.4 10.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.6 EGC39844.1 - 1.2e-08 34.3 10.1 0.067 13.3 0.0 5.5 5 0 0 5 5 5 3 Leucine Rich repeat SURF6 PF04935.12 EGC39844.1 - 0.4 10.4 2.3 0.8 9.5 2.3 1.5 1 0 0 1 1 1 0 Surfeit locus protein 6 Secretin_N_2 PF07655.13 EGC39844.1 - 2 9.0 16.6 0.6 10.7 12.8 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain PP2C PF00481.21 EGC39845.1 - 1e-61 208.9 0.0 1.2e-61 208.6 0.0 1.1 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.6 EGC39845.1 - 0.002 17.8 0.0 0.023 14.3 0.0 2.4 2 1 0 2 2 2 1 Protein phosphatase 2C 2-oxoacid_dh PF00198.23 EGC39845.1 - 0.016 14.7 0.0 0.022 14.2 0.0 1.2 1 0 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) zf-RING_2 PF13639.6 EGC39846.1 - 9e-12 45.1 5.6 1.4e-11 44.5 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC39846.1 - 1.8e-09 37.2 2.2 3.5e-09 36.2 2.2 1.5 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC39846.1 - 2.3e-08 34.2 3.6 4.2e-08 33.4 3.6 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC39846.1 - 4.6e-08 32.8 6.8 7.7e-08 32.1 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39846.1 - 3.3e-07 30.0 7.2 5.8e-07 29.3 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC39846.1 - 1.8e-06 27.8 8.4 2.7e-06 27.2 8.4 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39846.1 - 0.00014 21.9 2.2 0.00025 21.0 2.2 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.6 EGC39846.1 - 0.00028 20.7 6.5 0.00044 20.0 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGC39846.1 - 0.0004 20.0 6.4 0.00066 19.2 6.4 1.3 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type Prok-RING_4 PF14447.6 EGC39846.1 - 0.00093 19.0 6.5 0.0016 18.2 6.5 1.3 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC39846.1 - 0.0012 18.9 2.9 0.0023 18.0 2.9 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3H2C3 PF17122.5 EGC39846.1 - 0.017 15.1 1.6 0.041 13.9 1.6 1.6 1 0 0 1 1 1 0 Zinc-finger FANCL_C PF11793.8 EGC39846.1 - 0.27 11.4 5.3 0.65 10.2 5.3 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EGC39846.1 - 1.7 8.5 4.0 3.4 7.5 4.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING-like PF08746.11 EGC39846.1 - 2.4 8.5 5.8 4 7.8 5.8 1.4 1 0 0 1 1 1 0 RING-like domain PHD PF00628.29 EGC39846.1 - 5.8 6.9 9.1 9.9 6.2 9.1 1.4 1 0 0 1 1 1 0 PHD-finger RINGv PF12906.7 EGC39846.1 - 7.7 6.7 9.9 14 5.9 9.9 1.4 1 0 0 1 1 1 0 RING-variant domain RNB PF00773.19 EGC39847.1 - 8.4e-97 324.4 0.0 8.4e-97 324.4 0.0 2.5 3 1 0 3 3 3 1 RNB domain OB_Dis3 PF17849.1 EGC39847.1 - 1.2e-15 57.3 0.0 3.4e-15 55.8 0.0 1.9 1 0 0 1 1 1 1 Dis3-like cold-shock domain 2 (CSD2) Rrp44_CSD1 PF17216.3 EGC39847.1 - 2e-06 27.6 0.0 2e-06 27.6 0.0 2.7 3 0 0 3 3 3 1 Rrp44-like cold shock domain Dis3l2_C_term PF17877.1 EGC39847.1 - 0.07 13.5 0.0 0.07 13.5 0.0 4.3 5 0 0 5 5 5 0 DIS3-like exonuclease 2 C terminal RhoGAP PF00620.27 EGC39848.1 - 9.4e-33 113.2 0.3 9.4e-33 113.2 0.3 2.3 2 0 0 2 2 2 1 RhoGAP domain BAR_3 PF16746.5 EGC39848.1 - 1.5e-12 47.7 24.9 3.5e-12 46.5 24.9 1.7 1 0 0 1 1 1 1 BAR domain of APPL family BAR PF03114.18 EGC39848.1 - 6.8e-06 25.9 14.6 1.9e-05 24.4 14.6 1.8 1 1 0 1 1 1 1 BAR domain BAR_2 PF10455.9 EGC39848.1 - 1.1e-05 24.8 17.2 1.1e-05 24.8 17.2 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FliJ PF02050.16 EGC39848.1 - 0.021 15.0 2.9 0.021 15.0 2.9 2.3 1 1 1 2 2 2 0 Flagellar FliJ protein LIAS_N PF16881.5 EGC39848.1 - 0.21 12.0 2.7 0.34 11.3 0.9 2.3 2 0 0 2 2 2 0 N-terminal domain of lipoyl synthase of Radical_SAM family Bcr-Abl_Oligo PF09036.10 EGC39848.1 - 1.1 9.3 4.6 9.5 6.3 0.6 2.7 2 0 0 2 2 2 0 Bcr-Abl oncoprotein oligomerisation domain Cyt-b5 PF00173.28 EGC39849.1 - 4.3e-23 81.3 0.2 4.7e-23 81.1 0.2 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.23 EGC39851.1 - 5.5e-51 171.4 0.1 4.3e-25 88.0 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.18 EGC39851.1 - 2.7e-22 79.0 0.0 3.7e-11 42.8 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B KH_dom-like PF14714.6 EGC39851.1 - 3.3e-22 78.6 1.5 7.4e-22 77.5 1.5 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal GTP_EFTU PF00009.27 EGC39851.1 - 2.3e-19 69.7 0.1 4.4e-08 32.9 0.2 4.4 4 0 0 4 4 4 3 Elongation factor Tu GTP binding domain Dynamin_N PF00350.23 EGC39851.1 - 1.5e-15 57.7 0.3 0.0021 18.1 0.1 4.3 3 1 1 4 4 4 4 Dynamin family AIG1 PF04548.16 EGC39851.1 - 8.2e-12 44.9 0.1 3.6e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 AIG1 family Roc PF08477.13 EGC39851.1 - 1e-08 35.4 0.2 0.087 13.0 0.0 3.9 3 1 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase RsgA_GTPase PF03193.16 EGC39851.1 - 1.1e-07 32.0 0.0 0.26 11.2 0.0 4.2 4 0 0 4 4 4 2 RsgA GTPase Arf PF00025.21 EGC39851.1 - 6.5e-06 25.7 0.0 2.6 7.5 0.0 4.2 4 0 0 4 4 4 1 ADP-ribosylation factor family Ras PF00071.22 EGC39851.1 - 2.2e-05 24.1 0.0 0.58 9.7 0.0 3.5 2 2 0 2 2 2 2 Ras family Gtr1_RagA PF04670.12 EGC39851.1 - 3.3e-05 23.4 0.2 0.042 13.2 0.0 2.5 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region SRPRB PF09439.10 EGC39851.1 - 7.8e-05 22.2 0.1 0.016 14.6 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ABC_tran PF00005.27 EGC39851.1 - 0.00027 21.5 0.6 0.43 11.1 0.0 2.7 1 1 1 2 2 2 2 ABC transporter cobW PF02492.19 EGC39851.1 - 0.00067 19.3 0.7 6.8 6.2 0.1 4.0 3 1 0 4 4 4 0 CobW/HypB/UreG, nucleotide-binding domain MeaB PF03308.16 EGC39851.1 - 0.00076 18.5 0.1 10 5.0 0.0 3.7 3 1 1 4 4 4 0 Methylmalonyl Co-A mutase-associated GTPase MeaB Guanylate_kin PF00625.21 EGC39851.1 - 0.00094 18.9 0.2 0.18 11.5 0.1 2.6 2 1 0 2 2 2 1 Guanylate kinase AAA_24 PF13479.6 EGC39851.1 - 0.0011 18.7 1.0 2.9 7.6 0.1 3.4 3 1 0 3 3 3 2 AAA domain RNA_helicase PF00910.22 EGC39851.1 - 0.0041 17.5 0.0 4.6 7.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase MobB PF03205.14 EGC39851.1 - 0.0048 16.8 0.1 2.9 7.8 0.0 3.3 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B NTPase_1 PF03266.15 EGC39851.1 - 0.0064 16.4 0.2 2.4 8.1 0.0 2.8 3 0 0 3 3 3 1 NTPase AAA_22 PF13401.6 EGC39851.1 - 0.0067 16.7 0.0 1.4 9.2 0.0 3.0 2 2 0 2 2 2 1 AAA domain SRP54 PF00448.22 EGC39851.1 - 0.013 15.1 0.0 0.27 10.8 0.0 2.3 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain TniB PF05621.11 EGC39851.1 - 0.016 14.6 0.0 4.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Bacterial TniB protein AAA_18 PF13238.6 EGC39851.1 - 0.019 15.5 0.0 2.4 8.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain NB-ARC PF00931.22 EGC39851.1 - 0.032 13.4 0.0 8 5.6 0.0 2.4 2 0 0 2 2 2 0 NB-ARC domain ATPase_2 PF01637.18 EGC39851.1 - 0.032 14.1 2.3 7.4 6.4 0.0 3.1 3 1 0 3 3 3 0 ATPase domain predominantly from Archaea AAA PF00004.29 EGC39851.1 - 0.044 14.2 0.2 16 5.9 0.0 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGC39851.1 - 0.056 13.2 0.0 11 5.9 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain NOG1 PF06858.14 EGC39851.1 - 0.06 13.1 1.2 0.24 11.2 0.0 2.5 2 1 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) Ploopntkinase3 PF18751.1 EGC39851.1 - 0.082 12.8 0.0 13 5.7 0.0 2.2 2 0 0 2 2 2 0 P-loop Nucleotide Kinase3 PAP_assoc PF03828.19 EGC39851.1 - 0.092 13.0 0.0 0.28 11.4 0.0 1.8 1 0 0 1 1 1 0 Cid1 family poly A polymerase DUF3181 PF11378.8 EGC39851.1 - 0.1 12.9 0.0 0.3 11.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3181) INTS5_C PF14838.6 EGC39853.1 - 1.7e-20 73.3 0.5 1.7e-20 73.3 0.5 2.8 2 1 0 2 2 2 1 Integrator complex subunit 5 C-terminus Aldo_ket_red PF00248.21 EGC39854.1 - 2.7e-51 174.5 0.0 3.1e-51 174.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family FeS_assembly_P PF01883.19 EGC39855.1 - 8.3e-08 32.3 0.0 2.6e-07 30.7 0.0 1.8 1 1 0 1 1 1 1 Iron-sulfur cluster assembly protein FNIP PF05725.12 EGC39856.1 - 2.5e-46 155.6 67.9 5.9e-09 36.0 1.9 8.8 4 1 7 11 11 11 10 FNIP Repeat Ras PF00071.22 EGC39859.1 - 1.3e-42 145.2 0.0 1.5e-42 144.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39859.1 - 2.5e-29 101.9 0.0 5e-29 100.9 0.0 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39859.1 - 2.2e-15 56.5 0.0 3.2e-15 56.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.12 EGC39859.1 - 7.8e-06 25.4 0.0 9.4e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.27 EGC39859.1 - 2.6e-05 23.9 0.0 0.00011 21.8 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.23 EGC39859.1 - 3.9e-05 23.7 0.0 6.2e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.9 EGC39859.1 - 0.0008 19.2 0.0 0.0032 17.2 0.1 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation ATP_bind_1 PF03029.17 EGC39859.1 - 0.00081 19.2 0.3 0.003 17.4 0.0 1.7 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein TniB PF05621.11 EGC39859.1 - 0.0051 16.2 0.0 0.0085 15.5 0.0 1.4 1 0 0 1 1 1 1 Bacterial TniB protein SRPRB PF09439.10 EGC39859.1 - 0.0062 16.0 0.0 0.027 13.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit G-alpha PF00503.20 EGC39859.1 - 0.024 13.8 0.4 2.3 7.3 0.0 2.4 2 1 0 2 2 2 0 G-protein alpha subunit AAA_7 PF12775.7 EGC39859.1 - 0.029 13.9 0.0 0.046 13.2 0.0 1.3 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_14 PF13173.6 EGC39859.1 - 0.084 12.9 0.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain Ribosomal_L23 PF00276.20 EGC39860.1 - 5e-14 52.4 2.2 6.8e-14 52.0 2.2 1.2 1 0 0 1 1 1 1 Ribosomal protein L23 Asp23 PF03780.13 EGC39860.1 - 0.071 13.5 0.0 0.11 12.9 0.0 1.4 1 0 0 1 1 1 0 Asp23 family, cell envelope-related function VWA_2 PF13519.6 EGC39861.1 - 9.6e-22 77.7 0.7 3.4e-20 72.7 0.0 3.1 2 1 2 4 4 4 1 von Willebrand factor type A domain Ssl1 PF04056.14 EGC39861.1 - 1.8e-05 24.7 0.6 6.9e-05 22.8 0.1 2.0 3 0 0 3 3 3 1 Ssl1-like VWA PF00092.28 EGC39861.1 - 0.00018 21.8 0.1 0.00036 20.8 0.1 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain UIM PF02809.20 EGC39861.1 - 0.00051 19.8 10.0 0.055 13.4 0.3 3.2 3 0 0 3 3 3 2 Ubiquitin interaction motif STG PF15809.5 EGC39861.1 - 0.033 14.3 0.2 0.061 13.4 0.2 1.4 1 0 0 1 1 1 0 Simian taste bud-specific gene product family DUF676 PF05057.14 EGC39862.1 - 1.1e-39 136.2 0.9 1.1e-33 116.6 0.0 2.6 3 0 0 3 3 3 2 Putative serine esterase (DUF676) Palm_thioest PF02089.15 EGC39862.1 - 4.2e-07 30.1 0.0 9.1e-07 29.0 0.0 1.5 1 0 0 1 1 1 1 Palmitoyl protein thioesterase PGAP1 PF07819.13 EGC39862.1 - 1.1e-06 28.5 0.0 3.3e-06 27.0 0.0 1.8 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.25 EGC39862.1 - 2.7e-06 27.3 0.0 5.9e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) LCAT PF02450.15 EGC39862.1 - 0.00039 19.7 0.1 0.00081 18.7 0.0 1.7 1 1 0 1 1 1 1 Lecithin:cholesterol acyltransferase Hydrolase_4 PF12146.8 EGC39862.1 - 0.0082 15.4 0.0 0.5 9.6 0.0 2.3 2 0 0 2 2 2 1 Serine aminopeptidase, S33 Lipase PF00151.19 EGC39862.1 - 0.012 14.9 0.0 0.021 14.1 0.0 1.3 1 0 0 1 1 1 0 Lipase DUF915 PF06028.11 EGC39862.1 - 0.02 14.3 3.6 1.8 7.9 0.0 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Lipase_2 PF01674.18 EGC39862.1 - 0.028 14.0 0.1 0.073 12.6 0.1 1.7 1 1 0 1 1 1 0 Lipase (class 2) Glutaredoxin PF00462.24 EGC39863.1 - 4.2e-20 71.7 0.0 1e-18 67.2 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.20 EGC39863.1 - 5.1e-15 55.3 0.1 9.5e-15 54.5 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.6 EGC39863.1 - 3.4e-05 24.3 0.1 0.00024 21.5 0.0 2.4 1 1 1 2 2 2 1 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC39863.1 - 0.00017 21.0 0.5 0.00021 20.7 0.5 1.1 1 0 0 1 1 1 1 OST3 / OST6 family, transporter family Thioredoxin_8 PF13905.6 EGC39863.1 - 0.0002 21.7 1.9 0.049 14.0 0.1 2.9 2 2 1 3 3 3 2 Thioredoxin-like HyaE PF07449.11 EGC39863.1 - 0.01 15.8 0.0 0.059 13.3 0.0 2.2 3 0 0 3 3 3 0 Hydrogenase-1 expression protein HyaE Thioredoxin_3 PF13192.6 EGC39863.1 - 0.043 13.9 0.6 0.38 10.8 0.1 2.4 2 1 0 2 2 2 0 Thioredoxin domain Thioredoxin_7 PF13899.6 EGC39863.1 - 0.092 12.9 0.3 1.1 9.5 0.2 2.1 2 0 0 2 2 2 0 Thioredoxin-like AhpC-TSA PF00578.21 EGC39863.1 - 0.12 12.3 0.5 0.3 11.0 0.2 1.8 1 1 0 2 2 2 0 AhpC/TSA family F-box-like PF12937.7 EGC39864.1 - 5e-08 32.7 0.3 1.1e-07 31.6 0.3 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC39864.1 - 8.1e-08 32.0 0.4 1.6e-07 31.1 0.4 1.5 1 0 0 1 1 1 1 F-box domain F-box_4 PF15966.5 EGC39864.1 - 0.00029 20.7 0.0 0.00055 19.8 0.0 1.4 1 0 0 1 1 1 1 F-box PRKCSH PF07915.13 EGC39865.1 - 9.4e-13 49.0 0.7 9.4e-13 49.0 0.7 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein OSTbeta PF15048.6 EGC39865.1 - 0.11 12.6 6.2 0.53 10.4 6.2 2.0 1 1 0 1 1 1 0 Organic solute transporter subunit beta protein ABC2_membrane_3 PF12698.7 EGC39865.1 - 0.6 9.2 6.0 0.7 8.9 6.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Euplotes_phero PF05842.11 EGC39865.1 - 5 7.7 14.0 3.4 8.2 11.5 1.9 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein RabGAP-TBC PF00566.18 EGC39866.1 - 5.8e-53 179.7 1.2 5.8e-53 179.7 1.2 3.3 3 0 0 3 3 3 1 Rab-GTPase-TBC domain GRAM PF02893.20 EGC39866.1 - 1.2e-21 76.7 13.8 5.3e-12 45.6 6.9 3.5 2 1 1 3 3 3 2 GRAM domain Mito_carr PF00153.27 EGC39867.1 - 4.2e-73 241.4 3.2 1e-24 86.3 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein UL41A PF17591.2 EGC39868.1 - 3.2 7.9 6.6 0.24 11.5 0.9 2.1 2 0 0 2 2 2 0 Herpesvirus UL41A Erf4 PF10256.9 EGC39869.1 - 0.00051 20.1 3.7 0.0024 18.0 3.0 2.5 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family NLE PF08154.12 EGC39869.1 - 0.0037 17.8 1.4 0.12 12.9 0.1 3.3 3 0 0 3 3 3 1 NLE (NUC135) domain Sid-5 PF17204.3 EGC39869.1 - 0.34 11.1 0.1 0.34 11.1 0.1 2.4 2 0 0 2 2 2 0 Sid-5 family Erf4 PF10256.9 EGC39870.1 - 0.0009 19.3 7.0 0.0019 18.3 3.7 2.5 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF983 PF06170.12 EGC39870.1 - 0.75 10.2 7.0 0.64 10.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF983) Sm_multidrug_ex PF06695.11 EGC39870.1 - 0.86 10.2 11.3 0.16 12.6 3.4 2.3 2 0 0 2 2 2 0 Putative small multi-drug export protein MCU PF04678.13 EGC39870.1 - 2.5 8.2 4.9 0.96 9.5 2.4 1.6 1 1 1 2 2 2 0 Mitochondrial calcium uniporter Pkinase_Tyr PF07714.17 EGC39871.1 - 3.3e-35 121.6 0.0 7.7e-35 120.4 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC39871.1 - 5e-35 121.1 0.0 2e-34 119.1 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.23 EGC39871.1 - 9.4e-16 57.2 16.0 0.12 12.4 0.1 9.8 10 0 0 10 10 9 5 Armadillo/beta-catenin-like repeat LRR_9 PF14580.6 EGC39871.1 - 5.3e-10 39.1 5.0 6.4e-06 25.8 0.1 3.3 1 1 0 2 2 2 2 Leucine-rich repeat LRR_8 PF13855.6 EGC39871.1 - 2.4e-09 36.8 18.3 0.0004 20.1 0.3 5.2 5 0 0 5 5 5 3 Leucine rich repeat LRR_4 PF12799.7 EGC39871.1 - 6.2e-09 36.0 35.5 6.6e-05 23.2 0.1 6.5 5 1 0 6 6 4 4 Leucine Rich repeats (2 copies) HEAT_2 PF13646.6 EGC39871.1 - 0.00097 19.5 0.4 1.1 9.7 0.2 4.2 4 0 0 4 4 4 1 HEAT repeats LRR_1 PF00560.33 EGC39871.1 - 0.081 13.5 16.1 31 5.7 0.6 7.4 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.6 EGC39871.1 - 0.14 12.3 12.9 2 8.7 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich repeat RTP1_C1 PF10363.9 EGC39871.1 - 0.77 10.0 9.8 32 4.8 0.1 5.2 3 1 0 4 4 4 0 Required for nuclear transport of RNA pol II C-terminus 1 V-ATPase_H_C PF11698.8 EGC39871.1 - 0.77 9.9 16.2 0.13 12.4 0.3 5.4 3 1 2 6 6 6 0 V-ATPase subunit H HEAT PF02985.22 EGC39871.1 - 3.3 8.2 6.3 1.6e+02 2.9 0.0 5.2 5 0 0 5 5 4 0 HEAT repeat CTNNBL PF08216.11 EGC39871.1 - 6.1 7.1 14.7 60 3.9 0.1 6.5 6 1 1 8 8 8 0 Catenin-beta-like, Arm-motif containing nuclear DUF3361 PF11841.8 EGC39871.1 - 7.6 6.5 30.6 0.044 13.7 1.1 5.3 4 2 3 7 7 7 0 Domain of unknown function (DUF3361) Methyltransf_3 PF01596.17 EGC39872.1 - 4.5e-61 205.7 1.7 6e-61 205.3 1.7 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.6 EGC39872.1 - 1.5e-11 45.2 0.0 2.8e-11 44.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC39872.1 - 2.3e-06 27.5 2.4 2.9e-06 27.1 1.2 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC39872.1 - 7.7e-06 26.5 0.0 2.2e-05 25.1 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.15 EGC39872.1 - 0.0002 21.1 0.1 0.00053 19.7 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_15 PF09445.10 EGC39872.1 - 0.0026 17.4 0.1 0.0049 16.4 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase mRNA_stabil PF13929.6 EGC39872.1 - 0.0029 16.6 0.4 0.0055 15.7 0.4 1.5 1 0 0 1 1 1 1 mRNA stabilisation AFG1_ATPase PF03969.16 EGC39872.1 - 0.0066 15.4 0.1 0.04 12.8 0.0 2.1 3 0 0 3 3 3 1 AFG1-like ATPase Methyltransf_11 PF08241.12 EGC39872.1 - 0.0086 16.7 0.0 0.021 15.4 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.14 EGC39872.1 - 0.029 13.9 0.0 0.043 13.4 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain DUF1366 PF07104.11 EGC39872.1 - 0.036 13.8 0.1 0.48 10.1 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1366) TRM PF02005.16 EGC39872.1 - 0.072 12.2 0.1 0.092 11.9 0.1 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase DUF4441 PF14536.6 EGC39872.1 - 3.6 7.8 10.7 0.091 13.0 1.9 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4441) AMP-binding PF00501.28 EGC39873.1 - 4.1e-84 282.6 0.0 5e-84 282.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.6 EGC39873.1 - 3e-18 66.5 0.0 8.3e-18 65.2 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Mob1_phocein PF03637.17 EGC39874.1 - 4.5e-81 270.8 0.1 5.4e-81 270.6 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family TTL PF03133.15 EGC39875.1 - 1.8e-24 86.4 2.3 3e-24 85.7 2.3 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.6 EGC39875.1 - 7.6e-06 25.4 0.0 0.0021 17.4 0.0 2.3 2 0 0 2 2 2 2 YheC/D like ATP-grasp Bt_P21 PF05560.11 EGC39875.1 - 0.012 15.2 0.3 0.031 13.9 0.3 1.6 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ATPgrasp_ST PF14397.6 EGC39875.1 - 0.046 13.0 0.0 0.1 11.8 0.0 1.5 2 0 0 2 2 2 0 Sugar-transfer associated ATP-grasp ydhR PF08803.11 EGC39875.1 - 0.098 12.6 0.0 0.24 11.3 0.0 1.7 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR DnaJ PF00226.31 EGC39876.1 - 5e-17 61.8 1.6 5e-17 61.8 1.6 2.7 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.17 EGC39876.1 - 0.00036 20.4 0.6 0.001 19.0 0.6 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.28 EGC39876.1 - 0.015 15.1 0.2 0.036 13.9 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC39876.1 - 0.12 13.1 0.1 0.3 11.8 0.1 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC39876.1 - 0.15 12.4 0.0 0.31 11.4 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S6e PF01092.19 EGC39877.1 - 2.6e-54 182.5 0.2 2.6e-54 182.5 0.2 1.6 2 0 0 2 2 2 1 Ribosomal protein S6e HNH_5 PF14279.6 EGC39878.1 - 0.048 13.5 0.8 1.2 9.0 0.1 2.3 2 0 0 2 2 2 0 HNH endonuclease HypA PF01155.19 EGC39878.1 - 0.1 12.6 0.9 0.23 11.5 0.9 1.5 1 0 0 1 1 1 0 Hydrogenase/urease nickel incorporation, metallochaperone, hypA Zn-ribbon_8 PF09723.10 EGC39878.1 - 7.6 6.7 6.4 1.1 9.5 2.2 1.8 2 0 0 2 2 2 0 Zinc ribbon domain RRP36 PF06102.12 EGC39879.1 - 9.8e-41 139.5 26.2 9.8e-41 139.5 26.2 2.3 2 0 0 2 2 2 1 rRNA biogenesis protein RRP36 Methyltransf_28 PF02636.17 EGC39880.1 - 2.3e-43 148.7 0.9 5.2e-43 147.6 0.0 1.9 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase SF3a60_bindingd PF12108.8 EGC39880.1 - 0.039 13.8 5.2 11 6.0 0.1 4.1 3 0 0 3 3 3 0 Splicing factor SF3a60 binding domain FAM60A PF15396.6 EGC39880.1 - 7.1 6.6 8.7 18 5.3 8.7 1.6 1 0 0 1 1 1 0 Protein Family FAM60A ZapB PF06005.12 EGC39882.1 - 0.0052 17.2 18.0 0.12 12.9 5.8 2.4 1 1 1 2 2 2 2 Cell division protein ZapB GAS PF13851.6 EGC39882.1 - 0.008 15.6 7.0 0.008 15.6 7.0 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Utp12 PF04003.12 EGC39882.1 - 0.0082 16.4 0.3 0.0082 16.4 0.3 1.8 2 1 0 2 2 1 1 Dip2/Utp12 Family Phasin PF05597.11 EGC39882.1 - 0.016 15.2 4.6 0.016 15.2 4.6 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cnn_1N PF07989.11 EGC39882.1 - 0.027 14.6 16.9 0.26 11.5 6.1 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EGC39882.1 - 0.03 14.4 17.9 0.37 10.9 0.8 3.3 3 0 0 3 3 3 0 bZIP transcription factor Zein-binding PF04576.15 EGC39882.1 - 0.1 12.9 12.1 0.77 10.1 3.3 2.3 1 1 1 2 2 2 0 Zein-binding ATG16 PF08614.11 EGC39882.1 - 0.12 12.5 16.5 0.28 11.4 5.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CCDC85 PF10226.9 EGC39882.1 - 0.14 11.8 13.1 2.4 7.8 6.4 2.4 1 1 1 2 2 2 0 CCDC85 family Z1 PF10593.9 EGC39882.1 - 0.2 11.1 5.4 0.24 10.9 5.4 1.1 1 0 0 1 1 1 0 Z1 domain CtIP_N PF10482.9 EGC39882.1 - 0.35 10.9 13.3 1.2 9.2 1.8 2.3 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 EGC39882.1 - 1.1 8.5 13.6 0.62 9.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EGC39882.1 - 2.4 8.2 17.5 0.39 10.7 4.8 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 EGC39882.1 - 3.1 7.9 16.3 4.7 7.3 16.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NuDC PF16273.5 EGC39882.1 - 3.4 8.3 10.1 10 6.7 1.8 2.6 1 1 0 2 2 2 0 Nuclear distribution C domain Fib_alpha PF08702.10 EGC39882.1 - 4.9 7.3 14.1 11 6.2 13.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NRBF2 PF08961.10 EGC39882.1 - 5.8 6.5 14.9 2.4 7.7 3.2 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator MPS2 PF17060.5 EGC39882.1 - 6.2 6.0 14.1 2.2 7.4 4.7 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 APG6_N PF17675.1 EGC39882.1 - 7.1 7.2 16.1 0.97 10.0 4.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 EGC39882.1 - 9.1 6.6 15.3 0.33 11.2 3.3 3.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper ZapB PF06005.12 EGC39884.1 - 0.0052 17.2 18.0 0.12 12.9 5.8 2.4 1 1 1 2 2 2 2 Cell division protein ZapB GAS PF13851.6 EGC39884.1 - 0.008 15.6 7.0 0.008 15.6 7.0 2.0 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding Utp12 PF04003.12 EGC39884.1 - 0.0082 16.4 0.3 0.0082 16.4 0.3 1.8 2 1 0 2 2 1 1 Dip2/Utp12 Family Phasin PF05597.11 EGC39884.1 - 0.016 15.2 4.6 0.016 15.2 4.6 1.6 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) Cnn_1N PF07989.11 EGC39884.1 - 0.027 14.6 16.9 0.26 11.5 6.1 2.4 2 1 0 2 2 2 0 Centrosomin N-terminal motif 1 bZIP_1 PF00170.21 EGC39884.1 - 0.03 14.4 17.9 0.37 10.9 0.8 3.3 3 0 0 3 3 3 0 bZIP transcription factor Zein-binding PF04576.15 EGC39884.1 - 0.1 12.9 12.1 0.77 10.1 3.3 2.3 1 1 1 2 2 2 0 Zein-binding ATG16 PF08614.11 EGC39884.1 - 0.12 12.5 16.5 0.28 11.4 5.0 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) CCDC85 PF10226.9 EGC39884.1 - 0.14 11.8 13.1 2.4 7.8 6.4 2.4 1 1 1 2 2 2 0 CCDC85 family Z1 PF10593.9 EGC39884.1 - 0.2 11.1 5.4 0.24 10.9 5.4 1.1 1 0 0 1 1 1 0 Z1 domain CtIP_N PF10482.9 EGC39884.1 - 0.35 10.9 13.3 1.2 9.2 1.8 2.3 1 1 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain DUF3450 PF11932.8 EGC39884.1 - 1.1 8.5 13.6 0.62 9.3 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) TMF_DNA_bd PF12329.8 EGC39884.1 - 2.4 8.2 17.5 0.39 10.7 4.8 2.7 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding UPF0242 PF06785.11 EGC39884.1 - 3.1 7.9 16.3 4.7 7.3 16.3 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus NuDC PF16273.5 EGC39884.1 - 3.4 8.3 10.1 10 6.7 1.8 2.6 1 1 0 2 2 2 0 Nuclear distribution C domain Fib_alpha PF08702.10 EGC39884.1 - 4.9 7.3 14.1 11 6.2 13.8 1.8 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family NRBF2 PF08961.10 EGC39884.1 - 5.8 6.5 14.9 2.4 7.7 3.2 2.2 1 1 1 2 2 2 0 Nuclear receptor-binding factor 2, autophagy regulator MPS2 PF17060.5 EGC39884.1 - 6.2 6.0 14.1 2.2 7.4 4.7 2.0 1 1 1 2 2 2 0 Monopolar spindle protein 2 APG6_N PF17675.1 EGC39884.1 - 7.1 7.2 16.1 0.97 10.0 4.3 2.1 1 1 1 2 2 2 0 Apg6 coiled-coil region HALZ PF02183.18 EGC39884.1 - 9.1 6.6 15.3 0.33 11.2 3.3 3.3 4 1 0 4 4 4 0 Homeobox associated leucine zipper OTU PF02338.19 EGC39885.1 - 1.8e-12 47.9 1.9 2.5e-12 47.4 0.0 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease DUF2722 PF10846.8 EGC39885.1 - 9.4e-05 21.5 10.4 9.7e-05 21.5 10.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2722) TFIIA PF03153.13 EGC39885.1 - 0.0016 18.5 17.4 0.0018 18.3 17.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit MPM1 PF17234.2 EGC39885.1 - 0.0035 17.6 2.2 0.0048 17.2 2.2 1.3 1 0 0 1 1 1 1 Mitochondrial peculiar membrane protein 1 Gti1_Pac2 PF09729.9 EGC39885.1 - 0.014 15.5 0.8 0.015 15.4 0.8 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family MecA PF05389.12 EGC39885.1 - 0.019 14.6 1.7 0.027 14.1 1.7 1.3 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) V_ATPase_I PF01496.19 EGC39885.1 - 0.019 12.9 2.8 0.021 12.8 2.8 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Dad2 PF08654.10 EGC39885.1 - 0.021 15.2 6.3 13 6.2 0.0 2.5 2 1 0 2 2 2 0 DASH complex subunit Dad2 Pex14_N PF04695.13 EGC39885.1 - 0.025 15.2 12.4 0.037 14.7 12.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3808 PF10300.9 EGC39885.1 - 0.05 12.3 2.6 0.069 11.9 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Peptidase_C65 PF10275.9 EGC39885.1 - 0.058 12.8 8.1 10 5.4 0.0 3.0 2 1 0 3 3 3 0 Peptidase C65 Otubain Peroxin-13_N PF04088.13 EGC39885.1 - 0.063 13.6 0.8 0.11 12.7 0.8 1.3 1 0 0 1 1 1 0 Peroxin 13, N-terminal region CobT PF06213.12 EGC39885.1 - 0.13 11.6 5.4 0.19 11.1 5.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT DUF4834 PF16118.5 EGC39885.1 - 0.17 12.8 5.3 0.32 12.0 5.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) EMC3_TMCO1 PF01956.16 EGC39885.1 - 0.17 11.6 3.6 0.24 11.1 3.6 1.2 1 0 0 1 1 1 0 Integral membrane protein EMC3/TMCO1-like Hydin_ADK PF17213.3 EGC39885.1 - 0.18 12.0 2.8 0.27 11.5 2.8 1.3 1 0 0 1 1 1 0 Hydin Adenylate kinase-like domain Peptidase_S49_N PF08496.10 EGC39885.1 - 0.34 11.0 4.0 0.54 10.3 4.0 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Ndc1_Nup PF09531.10 EGC39885.1 - 0.37 9.4 7.3 0.49 9.0 7.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup ZYG-11_interact PF05884.12 EGC39885.1 - 0.48 9.8 2.4 0.58 9.5 2.4 1.2 1 0 0 1 1 1 0 Interactor of ZYG-11 SKA1 PF07160.12 EGC39885.1 - 0.6 9.9 10.4 0.89 9.4 10.4 1.2 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 WASH-7_C PF14746.6 EGC39885.1 - 0.72 9.5 7.0 2.4 7.8 6.3 1.9 2 0 0 2 2 2 0 WASH complex subunit 7, C-terminal DUF4175 PF13779.6 EGC39885.1 - 0.83 7.5 18.4 0.94 7.3 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Spt20 PF12090.8 EGC39885.1 - 1 8.9 27.6 1.6 8.3 27.6 1.3 1 0 0 1 1 1 0 Spt20 family Complex1_LYR_2 PF13233.6 EGC39885.1 - 1 10.1 10.8 0.37 11.6 7.0 2.2 2 1 0 2 2 2 0 Complex1_LYR-like SARAF PF06682.12 EGC39885.1 - 1.2 8.7 8.5 0.73 9.4 5.9 1.7 2 0 0 2 2 2 0 SOCE-associated regulatory factor of calcium homoeostasis Presenilin PF01080.17 EGC39885.1 - 1.3 7.8 5.1 1.6 7.4 5.1 1.1 1 0 0 1 1 1 0 Presenilin UPF0560 PF10577.9 EGC39885.1 - 2.2 6.7 10.9 2.7 6.4 10.9 1.1 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 MscS_TM PF12794.7 EGC39885.1 - 7 5.4 5.9 9.4 5.0 5.9 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 RRM_2 PF04059.12 EGC39887.1 - 7.5e-24 83.8 1.7 1.9e-23 82.5 0.4 1.8 1 1 1 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.22 EGC39887.1 - 2.5e-06 27.2 0.0 4.3e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Smg4_UPF3 PF03467.15 EGC39887.1 - 6.9e-05 22.9 0.3 8.6e-05 22.6 0.3 1.2 1 0 0 1 1 1 1 Smg-4/UPF3 family 2Fe-2S_thioredx PF01257.19 EGC39887.1 - 0.014 15.3 0.1 0.014 15.2 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin DUF3453 PF11935.8 EGC39887.1 - 0.11 12.2 0.0 0.14 11.8 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3453) Zip PF02535.22 EGC39889.1 - 0.12 11.5 0.3 0.15 11.3 0.3 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC39889.1 - 0.19 10.5 9.8 0.3 9.8 9.8 1.2 1 0 0 1 1 1 0 Presenilin Herpes_U15 PF05613.11 EGC39889.1 - 0.44 11.3 4.6 0.4 11.4 1.2 2.5 2 0 0 2 2 2 0 Human herpesvirus U15 protein Cyclin_N PF00134.23 EGC39890.1 - 0.0018 18.0 0.3 0.0031 17.2 0.3 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.11 EGC39890.1 - 0.0047 17.3 1.2 0.015 15.7 1.2 2.0 1 1 0 1 1 1 1 Cyclin Mpp10 PF04006.12 EGC39891.1 - 2.4e-141 472.2 130.7 8e-141 470.5 130.7 1.7 1 1 0 1 1 1 1 Mpp10 protein Ras PF00071.22 EGC39892.1 - 1.4e-22 80.0 0.0 2e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39892.1 - 5.3e-07 29.9 0.0 1.4e-06 28.5 0.0 1.7 1 1 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase PPR_2 PF13041.6 EGC39893.1 - 0.00075 19.6 0.2 1.9 8.8 0.0 2.8 2 0 0 2 2 2 2 PPR repeat family Spore_III_AB PF09548.10 EGC39893.1 - 0.094 12.8 1.9 0.31 11.1 0.2 2.6 3 0 0 3 3 3 0 Stage III sporulation protein AB (spore_III_AB) zf-Di19 PF05605.12 EGC39894.1 - 1.7e-06 28.2 7.1 1.7e-06 28.2 7.1 2.9 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding NPR1_like_C PF12313.8 EGC39894.1 - 0.027 14.0 0.1 0.04 13.4 0.1 1.3 1 0 0 1 1 1 0 NPR1/NIM1 like defence protein C terminal zf-H2C2_2 PF13465.6 EGC39894.1 - 0.1 13.1 0.4 0.1 13.1 0.4 5.4 7 0 0 7 7 7 0 Zinc-finger double domain Thioredoxin PF00085.20 EGC39895.1 - 6.4e-28 96.8 0.3 2.4e-26 91.7 0.1 3.0 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.6 EGC39895.1 - 2.9e-10 40.4 9.3 4.7e-07 29.9 5.4 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain OST3_OST6 PF04756.13 EGC39895.1 - 4e-07 29.7 2.2 0.00035 20.0 0.0 3.5 3 1 0 3 3 3 2 OST3 / OST6 family, transporter family Thioredoxin_2 PF13098.6 EGC39895.1 - 2.5e-06 27.9 0.5 0.00029 21.3 0.1 3.0 2 1 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.6 EGC39895.1 - 0.00048 20.4 3.6 0.76 10.2 3.6 3.9 1 1 0 1 1 1 1 Thioredoxin-like DUF3242 PF11586.8 EGC39895.1 - 0.022 14.5 2.6 0.054 13.2 0.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3242) FNIP PF05725.12 EGC39896.1 - 5e-171 554.7 75.9 3.4e-15 55.9 1.0 11.9 4 2 11 16 16 16 16 FNIP Repeat MCM_OB PF17207.3 EGC39896.1 - 0.0048 16.7 0.0 31 4.4 0.0 5.4 5 3 2 8 8 8 1 MCM OB domain DDE_3 PF13358.6 EGC39897.1 - 0.00011 21.9 0.3 0.00029 20.6 0.1 1.7 2 0 0 2 2 2 1 DDE superfamily endonuclease ketoacyl-synt PF00109.26 EGC39898.1 - 3.1e-62 210.4 0.0 5.4e-62 209.6 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC39898.1 - 1.8e-44 152.6 0.0 2.9e-44 151.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.12 EGC39898.1 - 7e-43 146.6 0.0 2.2e-42 145.0 0.0 1.9 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.22 EGC39898.1 - 9.5e-33 112.7 0.0 2e-32 111.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC39898.1 - 1.5e-27 96.6 0.0 3.6e-25 88.9 0.0 2.7 2 0 0 2 2 2 1 KR domain PS-DH PF14765.6 EGC39898.1 - 2.6e-19 69.6 0.0 3.9e-19 69.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC39898.1 - 9e-11 42.2 0.1 5.3e-10 39.7 0.0 2.4 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension Polysacc_synt_2 PF02719.15 EGC39898.1 - 1.5e-08 34.1 2.1 3.1e-05 23.3 0.3 2.5 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.19 EGC39898.1 - 2.5e-07 30.0 0.5 7.3e-07 28.5 0.5 1.8 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.21 EGC39898.1 - 4.2e-07 29.7 0.1 1.8e-06 27.6 0.0 2.1 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.26 EGC39898.1 - 1.2e-06 28.6 0.0 2.9e-06 27.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC39898.1 - 9.5e-06 26.7 0.0 2.3e-05 25.4 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.12 EGC39898.1 - 2.5e-05 24.9 0.6 0.00022 21.9 0.0 3.1 2 1 1 3 3 2 1 Methyltransferase domain PP-binding PF00550.25 EGC39898.1 - 2.7e-05 24.4 0.2 6.5e-05 23.2 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.12 EGC39898.1 - 0.00012 21.9 0.0 0.00025 20.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain GDP_Man_Dehyd PF16363.5 EGC39898.1 - 0.0024 17.3 0.1 0.0064 15.9 0.1 1.7 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Thiolase_N PF00108.23 EGC39898.1 - 0.0033 16.8 0.0 0.0063 15.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.6 EGC39898.1 - 0.13 12.1 0.0 0.41 10.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Claudin_3 PF06653.11 EGC39900.1 - 0.024 14.6 0.4 0.024 14.6 0.4 1.5 2 0 0 2 2 2 0 Tight junction protein, Claudin-like TIG PF01833.24 EGC39901.1 - 2.1e-05 24.5 1.7 2.1e-05 24.5 1.7 5.3 5 2 1 6 6 6 2 IPT/TIG domain EGF_2 PF07974.13 EGC39901.1 - 0.00011 22.5 31.3 0.00036 20.8 11.3 3.2 2 0 0 2 2 2 2 EGF-like domain DUF3377 PF11857.8 EGC39901.1 - 0.015 15.2 0.1 0.036 14.0 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) Laminin_EGF PF00053.24 EGC39901.1 - 0.053 13.7 22.7 0.73 10.0 8.9 3.0 2 0 0 2 2 2 0 Laminin EGF domain CCB1 PF12046.8 EGC39901.1 - 0.19 11.1 1.6 0.27 10.5 0.0 1.9 2 0 0 2 2 2 0 Cofactor assembly of complex C subunit B LRR_6 PF13516.6 EGC39901.1 - 1.5 9.1 6.9 0.59 10.3 0.7 3.8 3 0 0 3 3 3 0 Leucine Rich repeat Brr6_like_C_C PF10104.9 EGC39902.1 - 1.1e-10 41.5 19.7 2.1e-10 40.5 0.7 3.4 2 1 1 3 3 3 2 Di-sulfide bridge nucleocytoplasmic transport domain 7TM_GPCR_Srw PF10324.9 EGC39902.1 - 0.00021 20.7 11.8 0.0044 16.3 3.5 2.4 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF898 PF05987.13 EGC39902.1 - 0.0052 15.9 0.5 0.0052 15.9 0.5 1.9 2 0 0 2 2 2 1 Bacterial protein of unknown function (DUF898) 7tm_1 PF00001.21 EGC39902.1 - 0.14 11.4 7.9 0.98 8.7 7.9 1.9 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.8 EGC39902.1 - 0.47 10.6 6.3 0.21 11.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) TMEM154 PF15102.6 EGC39902.1 - 3.3 7.6 10.0 0.14 12.1 1.6 2.3 1 1 1 2 2 2 0 TMEM154 protein family Mdv1 PF11542.8 EGC39903.1 - 0.58 10.2 4.6 3.2 7.8 0.6 2.7 2 0 0 2 2 2 0 Mitochondrial division protein 1 RuBisCO_large_N PF02788.16 EGC39904.1 - 0.047 13.9 0.0 0.076 13.2 0.0 1.4 1 0 0 1 1 1 0 Ribulose bisphosphate carboxylase large chain, N-terminal domain DUF4834 PF16118.5 EGC39905.1 - 0.0025 18.8 1.3 0.0039 18.1 1.3 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4834) DUF3854 PF12965.7 EGC39905.1 - 0.039 13.9 0.4 0.053 13.5 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) FAM176 PF14851.6 EGC39905.1 - 0.052 13.2 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 FAM176 family EutQ PF06249.12 EGC39905.1 - 0.072 12.9 1.1 0.096 12.4 1.1 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ DUF2066 PF09839.9 EGC39906.1 - 0.14 11.6 0.0 0.14 11.6 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2066) Herpes_UL49_5 PF05702.11 EGC39907.1 - 0.047 13.8 0.0 0.051 13.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein zf-RING_2 PF13639.6 EGC39908.1 - 1.5e-09 38.0 7.8 3.1e-09 37.0 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39908.1 - 9.6e-09 35.0 4.8 1.9e-08 34.0 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC39908.1 - 4.1e-08 32.9 7.4 7.4e-08 32.1 7.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC39908.1 - 2.5e-07 30.5 9.2 5.4e-07 29.4 9.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39908.1 - 2.7e-07 30.8 4.9 1e-06 28.9 4.9 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC39908.1 - 3.9e-05 23.4 5.2 8.8e-05 22.3 5.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC39908.1 - 9.7e-05 22.3 6.0 0.00026 20.9 6.0 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC39908.1 - 0.00014 21.8 6.7 0.00033 20.5 6.7 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC39908.1 - 0.0043 17.1 1.5 0.0081 16.2 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC39908.1 - 0.0054 16.9 9.0 0.015 15.4 9.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING DUF4834 PF16118.5 EGC39908.1 - 0.013 16.4 0.4 0.013 16.4 0.4 5.2 3 1 0 3 3 2 0 Domain of unknown function (DUF4834) zf-RING_11 PF17123.5 EGC39908.1 - 0.065 13.0 7.1 0.13 12.0 7.1 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_4 PF14570.6 EGC39908.1 - 0.72 9.7 9.0 1.5 8.7 9.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain API5 PF05918.11 EGC39910.1 - 1.2e-70 238.9 18.8 1.4e-70 238.6 18.8 1.0 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) WASH_WAHD PF11945.8 EGC39911.1 - 4.4e-54 184.0 2.7 6.7e-54 183.4 2.7 1.2 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.20 EGC39911.1 - 0.00026 20.7 0.4 0.00051 19.8 0.4 1.5 1 0 0 1 1 1 1 WH2 motif Cwf_Cwc_15 PF04889.12 EGC39911.1 - 0.0077 16.0 7.1 0.58 9.8 0.0 2.6 2 0 0 2 2 2 1 Cwf15/Cwc15 cell cycle control protein FAM176 PF14851.6 EGC39911.1 - 3.6 7.2 11.2 3.5 7.3 4.5 2.5 2 0 0 2 2 2 0 FAM176 family TLP-20 PF06088.11 EGC39911.1 - 7.7 6.4 10.6 17 5.3 1.0 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Peroxin-13_N PF04088.13 EGC39912.1 - 4.4e-26 91.9 0.9 4.4e-26 91.9 0.9 3.2 2 1 0 2 2 2 1 Peroxin 13, N-terminal region SH3_9 PF14604.6 EGC39912.1 - 2.8e-14 52.7 0.2 4.9e-14 51.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC39912.1 - 6.7e-14 51.2 0.0 1.3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.17 EGC39912.1 - 1.1e-12 47.4 0.0 2.7e-12 46.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain Got1 PF04178.12 EGC39913.1 - 1.9e-15 57.3 12.9 2.4e-15 56.9 12.9 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family DUF1129 PF06570.11 EGC39913.1 - 2.4 7.6 6.6 3.6 7.0 6.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) Peptidase_S9 PF00326.21 EGC39915.1 - 1.2e-43 149.1 0.0 2.2e-43 148.2 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.15 EGC39915.1 - 2.6e-32 112.1 3.1 5e-32 111.2 3.1 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Hydrolase_4 PF12146.8 EGC39915.1 - 0.055 12.7 0.0 0.1 11.8 0.0 1.3 1 0 0 1 1 1 0 Serine aminopeptidase, S33 Clr2 PF10383.9 EGC39916.1 - 0.12 13.1 3.2 0.14 12.9 3.2 1.1 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 Chromo PF00385.24 EGC39918.1 - 1.1e-13 50.9 1.7 1.2e-13 50.8 1.7 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.8 EGC39918.1 - 0.011 15.6 0.3 0.012 15.5 0.3 1.1 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain DUF885 PF05960.11 EGC39920.1 - 0.066 12.8 0.0 0.069 12.8 0.0 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) Spuma_A9PTase PF03539.14 EGC39920.1 - 0.088 12.9 0.2 0.1 12.8 0.2 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Chromo PF00385.24 EGC39921.1 - 3.1e-15 55.8 1.7 3.5e-15 55.7 1.7 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mtf2_C PF14061.6 EGC39921.1 - 0.041 14.0 0.1 0.057 13.6 0.1 1.3 1 0 0 1 1 1 0 Polycomb-like MTF2 factor 2 Lip_prot_lig_C PF10437.9 EGC39921.1 - 0.075 13.0 0.1 0.094 12.7 0.1 1.1 1 0 0 1 1 1 0 Bacterial lipoate protein ligase C-terminus Aminotran_5 PF00266.19 EGC39922.1 - 6.7e-05 22.0 0.0 8.2e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Herpes_UL49_5 PF05702.11 EGC39922.1 - 0.055 13.6 0.0 0.08 13.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Pkinase PF00069.25 EGC39923.1 - 4.5e-21 75.4 0.4 4.5e-21 75.4 0.4 2.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39923.1 - 7.3e-12 45.1 0.0 1.4e-11 44.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1084 PF06454.11 EGC39924.1 - 1.6e-09 37.5 30.3 4.4e-09 36.1 30.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) T2SSF PF00482.23 EGC39924.1 - 2.1 8.3 0.0 2.1 8.3 0.0 2.6 3 0 0 3 3 3 0 Type II secretion system (T2SS), protein F GFP PF01353.22 EGC39925.1 - 0.062 12.8 0.0 0.073 12.5 0.0 1.1 1 0 0 1 1 1 0 Green fluorescent protein DUF1080 PF06439.11 EGC39925.1 - 0.1 12.7 0.0 0.11 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DUF1084 PF06454.11 EGC39926.1 - 4.6e-15 55.7 28.6 1.1e-14 54.5 28.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) p450 PF00067.22 EGC39927.1 - 5.9e-84 282.5 0.2 6.6e-84 282.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECH_2 PF16113.5 EGC39927.1 - 0.1 12.1 0.0 0.16 11.4 0.0 1.2 1 0 0 1 1 1 0 Enoyl-CoA hydratase/isomerase Crinivirus_P26 PF07416.11 EGC39927.1 - 0.82 9.3 7.1 0.27 10.9 0.6 2.7 3 0 0 3 3 3 0 Crinivirus P26 protein p450 PF00067.22 EGC39928.1 - 3.5e-82 276.6 0.1 4.2e-82 276.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 OTU PF02338.19 EGC39928.1 - 0.066 13.7 0.1 0.82 10.2 0.0 2.3 2 0 0 2 2 2 0 OTU-like cysteine protease p450 PF00067.22 EGC39929.1 - 5.1e-87 292.6 0.0 6e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 rhaM PF05336.13 EGC39929.1 - 0.12 12.4 0.0 0.56 10.3 0.0 1.9 2 0 0 2 2 2 0 L-rhamnose mutarotase p450 PF00067.22 EGC39930.1 - 2.8e-83 280.2 0.0 3.5e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.25 EGC39931.1 - 2.9e-59 200.6 30.5 1.3e-20 73.9 1.5 4.4 4 1 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39931.1 - 1.1e-30 106.8 3.6 2.8e-12 46.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.14 EGC39931.1 - 4.5e-11 42.5 0.4 0.00066 19.1 0.0 3.1 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase_fungal PF17667.1 EGC39931.1 - 3.2e-09 36.1 0.9 0.014 14.2 0.1 3.4 3 0 0 3 3 3 3 Fungal protein kinase APH PF01636.23 EGC39931.1 - 9e-06 25.8 0.0 0.76 9.7 0.0 4.0 3 2 2 5 5 5 2 Phosphotransferase enzyme family FTA2 PF13095.6 EGC39931.1 - 0.0068 16.0 1.2 1.2 8.7 0.1 3.0 2 0 0 2 2 2 2 Kinetochore Sim4 complex subunit FTA2 DHQS PF01959.16 EGC39931.1 - 0.11 11.4 1.1 1.5 7.6 0.1 2.4 2 0 0 2 2 2 0 3-dehydroquinate synthase II DUF2153 PF09921.9 EGC39931.1 - 0.22 11.3 8.3 4.1 7.2 0.1 3.9 3 1 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2153) FERM_N_2 PF18038.1 EGC39931.1 - 8.3 7.3 11.0 37 5.3 0.2 5.3 4 0 0 4 4 4 0 FERM N-terminal domain Spuma_A9PTase PF03539.14 EGC39932.1 - 0.038 14.1 0.2 0.045 13.9 0.2 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Ion_trans PF00520.31 EGC39932.1 - 0.058 12.6 0.3 0.063 12.5 0.3 1.1 1 0 0 1 1 1 0 Ion transport protein Plk4_PB2 PF18409.1 EGC39932.1 - 0.23 12.2 2.0 0.38 11.5 2.0 1.5 1 1 0 1 1 1 0 Polo-like Kinase 4 Polo Box 2 ABC2_membrane_3 PF12698.7 EGC39932.1 - 0.53 9.3 2.3 0.7 8.9 2.3 1.2 1 1 0 1 1 1 0 ABC-2 family transporter protein TssO PF17561.2 EGC39932.1 - 1.2 9.2 10.1 1.1 9.4 1.5 2.1 1 1 0 2 2 2 0 Type VI secretion system, TssO Dicty_REP PF05086.12 EGC39934.1 - 3.4e-33 114.7 9.8 3.9e-33 114.5 9.8 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein UCH_N PF16674.5 EGC39934.1 - 0.013 15.4 1.1 0.027 14.4 0.6 1.8 2 0 0 2 2 2 0 N-terminal of ubiquitin carboxyl-terminal hydrolase 37 Ependymin PF00811.18 EGC39935.1 - 0.072 13.4 2.8 0.21 11.8 1.0 2.4 2 1 0 2 2 2 0 Ependymin Chromo PF00385.24 EGC39936.1 - 2.6e-15 56.0 2.2 2.9e-15 55.9 2.2 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain EGF_Tenascin PF18720.1 EGC39938.1 - 0.043 13.9 7.4 0.096 12.8 7.4 1.6 1 0 0 1 1 1 0 Tenascin EGF domain EphA2_TM PF14575.6 EGC39938.1 - 1.9 9.4 5.7 0.66 10.9 1.0 2.3 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Cpn60_TCP1 PF00118.24 EGC39939.1 - 1.8e-148 495.2 14.9 2.1e-148 495.0 14.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nefa_Nip30_N PF10187.9 EGC39940.1 - 5.1e-12 46.1 14.8 5.1e-12 46.1 14.8 2.6 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 AAA_15 PF13175.6 EGC39940.1 - 1.4 8.5 41.0 1.7 8.2 41.0 1.1 1 0 0 1 1 1 0 AAA ATPase domain THRAP3_BCLAF1 PF15440.6 EGC39940.1 - 3.9 6.4 34.5 4.7 6.1 34.5 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family DUF572 PF04502.13 EGC39940.1 - 4.2 6.9 37.8 5.7 6.5 37.8 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) Rad17 PF03215.15 EGC39941.1 - 1.9e-19 70.3 0.2 1.9e-19 70.3 0.2 2.6 2 0 0 2 2 2 1 Rad17 P-loop domain AAA_16 PF13191.6 EGC39941.1 - 4.6e-05 23.9 0.0 0.0001 22.7 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain RsgA_GTPase PF03193.16 EGC39941.1 - 0.00018 21.4 0.9 0.0013 18.6 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AAA_22 PF13401.6 EGC39941.1 - 0.00027 21.2 3.9 0.02 15.2 0.5 4.1 3 1 0 3 3 3 1 AAA domain AAA PF00004.29 EGC39941.1 - 0.0003 21.2 0.0 0.00095 19.6 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.6 EGC39941.1 - 0.0014 18.8 0.0 0.0042 17.3 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.6 EGC39941.1 - 0.0019 18.7 0.0 0.0019 18.7 0.0 3.4 3 0 0 3 3 3 1 AAA domain ABC_tran PF00005.27 EGC39941.1 - 0.0028 18.1 1.8 0.0098 16.4 0.0 2.9 2 0 0 2 2 2 1 ABC transporter RNA_helicase PF00910.22 EGC39941.1 - 0.0052 17.2 2.8 0.044 14.2 0.0 3.7 2 1 0 2 2 2 1 RNA helicase AAA_29 PF13555.6 EGC39941.1 - 0.016 15.0 0.1 0.044 13.5 0.1 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_5 PF07728.14 EGC39941.1 - 0.018 15.0 0.0 0.046 13.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) NB-ARC PF00931.22 EGC39941.1 - 0.021 14.0 0.2 0.063 12.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain NTPase_1 PF03266.15 EGC39941.1 - 0.037 13.9 0.1 0.094 12.6 0.1 1.7 1 0 0 1 1 1 0 NTPase TsaE PF02367.17 EGC39941.1 - 0.043 13.8 0.0 0.14 12.2 0.0 1.8 2 0 0 2 2 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_14 PF13173.6 EGC39941.1 - 0.046 13.7 0.0 0.046 13.7 0.0 3.7 4 1 0 4 4 3 0 AAA domain RuvB_N PF05496.12 EGC39941.1 - 0.2 11.4 0.0 0.45 10.3 0.0 1.5 1 0 0 1 1 1 0 Holliday junction DNA helicase RuvB P-loop domain zf-CCHH PF10283.9 EGC39941.1 - 4 7.5 8.0 0.072 13.1 0.4 2.0 2 0 0 2 2 1 0 PBZ domain zf-DNL PF05180.12 EGC39943.1 - 9.2e-27 92.8 0.5 1.8e-26 91.8 0.5 1.5 1 0 0 1 1 1 1 DNL zinc finger Trm5_N PF18093.1 EGC39943.1 - 0.77 9.7 4.7 0.34 10.9 0.8 2.3 2 0 0 2 2 2 0 tRNA methyltransferase 5 N-terminal domain Ras PF00071.22 EGC39944.1 - 9.1e-44 148.9 0.0 1.1e-43 148.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC39944.1 - 1.7e-18 66.9 0.0 3e-18 66.2 0.0 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC39944.1 - 0.00036 20.0 0.0 0.00074 19.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_Rpb2_2 PF04561.14 EGC39944.1 - 0.028 14.0 0.0 0.064 12.9 0.0 1.5 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 2 GTP_EFTU PF00009.27 EGC39944.1 - 0.13 11.8 0.2 1 8.9 0.0 2.4 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain TPR_17 PF13431.6 EGC39945.1 - 2.1e-06 27.7 0.4 1.7e-05 24.8 0.2 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat DUF4834 PF16118.5 EGC39946.1 - 0.013 16.4 0.3 0.013 16.4 0.3 3.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4834) Peptidase_M56 PF05569.11 EGC39946.1 - 0.13 11.4 0.8 0.29 10.3 0.8 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 OTU PF02338.19 EGC39948.1 - 2.6e-11 44.1 0.0 4.8e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.13 EGC39948.1 - 0.018 15.0 37.4 0.026 14.5 37.4 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF3854 PF12965.7 EGC39949.1 - 0.036 14.0 0.5 0.052 13.5 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3854) Chromo PF00385.24 EGC39950.1 - 1.3e-15 57.0 1.1 1.4e-15 56.9 1.1 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Mito_fiss_reg PF05308.11 EGC39951.1 - 1.2 9.2 7.5 0.063 13.3 2.0 1.6 2 0 0 2 2 2 0 Mitochondrial fission regulator SGT1 PF07093.11 EGC39952.1 - 9.9e-104 347.9 46.9 1.3e-100 337.6 46.9 2.5 1 1 0 1 1 1 1 SGT1 protein AI-2E_transport PF01594.16 EGC39952.1 - 4.9 6.2 5.3 4.6 6.3 0.1 2.6 2 1 0 2 2 2 0 AI-2E family transporter Ribosomal_L38e PF01781.18 EGC39953.1 - 1.9e-28 98.3 2.8 2.2e-28 98.2 2.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family ERG4_ERG24 PF01222.17 EGC39954.1 - 1e-75 255.2 15.0 1.2e-75 254.9 15.0 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.12 EGC39954.1 - 3.2e-07 30.1 2.2 5.5e-07 29.3 2.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GATA PF00320.27 EGC39955.1 - 1.6e-16 59.6 4.0 3.3e-16 58.6 4.0 1.6 1 0 0 1 1 1 1 GATA zinc finger zinc_ribbon_9 PF14369.6 EGC39955.1 - 0.24 11.7 0.4 0.49 10.7 0.4 1.5 1 0 0 1 1 1 0 zinc-ribbon Secretin_N_2 PF07655.13 EGC39956.1 - 2.6 8.6 10.7 4.8 7.8 10.7 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Med3 PF11593.8 EGC39956.1 - 5.1 6.2 18.0 8.9 5.4 18.0 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal NMD3 PF04981.13 EGC39957.1 - 6.3e-82 274.7 5.8 1e-81 274.0 5.8 1.3 1 0 0 1 1 1 1 NMD3 family rRNA_processing PF08524.11 EGC39957.1 - 0.071 13.1 5.8 0.054 13.5 4.2 1.6 1 1 0 1 1 1 0 rRNA processing zf-3CxxC PF13695.6 EGC39957.1 - 1.1 9.8 4.1 0.54 10.8 0.2 2.2 2 0 0 2 2 2 0 Zinc-binding domain CCDC53 PF10152.9 EGC39959.1 - 2.6e-12 47.4 1.2 2.6e-12 47.4 1.2 2.6 2 1 0 2 2 2 1 Subunit CCDC53 of WASH complex Fer2 PF00111.27 EGC39960.1 - 4.6e-12 45.7 1.6 5.9e-12 45.4 1.6 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain zf-C3HC4_3 PF13920.6 EGC39961.1 - 4.6e-09 36.0 6.4 7e-09 35.4 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39961.1 - 8.1e-07 29.3 7.5 1.3e-06 28.6 7.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC39961.1 - 5.4e-06 26.1 7.6 8.8e-06 25.5 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC39961.1 - 5.2e-05 23.1 7.5 9e-05 22.4 7.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGC39961.1 - 6.5e-05 22.7 8.3 0.00014 21.6 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC39961.1 - 0.00011 22.1 2.8 0.00037 20.5 2.8 1.9 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.6 EGC39961.1 - 0.00017 21.3 8.7 0.0008 19.2 8.7 2.0 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-rbx1 PF12678.7 EGC39961.1 - 0.002 18.4 4.5 0.006 16.9 4.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-Di19 PF05605.12 EGC39961.1 - 0.0024 18.1 0.9 0.19 12.1 0.1 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding TFIIA PF03153.13 EGC39961.1 - 0.01 15.8 7.0 0.012 15.7 7.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-C3HC4_4 PF15227.6 EGC39961.1 - 0.013 15.6 7.4 0.33 11.2 7.1 2.8 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DZR PF12773.7 EGC39961.1 - 0.13 12.3 4.2 0.24 11.5 4.2 1.4 1 0 0 1 1 1 0 Double zinc ribbon Lin-8 PF03353.15 EGC39961.1 - 0.16 11.5 9.5 0.21 11.1 9.5 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4428 PF14471.6 EGC39961.1 - 0.64 10.0 8.3 7.8 6.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) LapA_dom PF06305.11 EGC39961.1 - 0.69 9.8 2.6 1.1 9.1 0.0 2.3 2 0 0 2 2 1 0 Lipopolysaccharide assembly protein A domain DUF3915 PF13054.6 EGC39961.1 - 1 9.3 7.1 1.5 8.8 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) zf-UDP PF14569.6 EGC39961.1 - 3.3 7.9 7.1 9.1 6.5 7.1 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-RING_4 PF14570.6 EGC39961.1 - 4.3 7.2 11.6 24 4.8 11.6 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.6 EGC39962.1 - 2e-10 40.8 11.0 3.3e-10 40.1 11.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC39962.1 - 2e-08 34.0 11.8 3.3e-08 33.2 11.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC39962.1 - 2.1e-08 33.9 7.5 3.3e-08 33.2 7.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC39962.1 - 2.9e-07 30.7 9.6 8.7e-07 29.1 9.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC39962.1 - 3.6e-07 29.9 12.1 7.1e-07 29.0 12.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC39962.1 - 4.6e-05 23.2 6.1 9.4e-05 22.2 6.1 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC39962.1 - 0.00039 20.3 9.7 0.00071 19.5 9.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39962.1 - 0.0031 17.5 5.4 0.0073 16.3 5.4 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.6 EGC39962.1 - 0.012 15.4 10.4 0.022 14.5 10.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_10 PF16685.5 EGC39962.1 - 0.032 14.4 4.9 0.066 13.4 4.9 1.5 1 0 0 1 1 1 0 zinc RING finger of MSL2 IBR PF01485.21 EGC39962.1 - 0.044 14.0 10.8 0.12 12.6 10.8 1.8 1 0 0 1 1 1 0 IBR domain, a half RING-finger domain zf-C3HC4_4 PF15227.6 EGC39962.1 - 0.074 13.2 10.7 0.11 12.6 9.1 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC39962.1 - 0.078 13.0 4.5 0.17 11.9 4.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC39962.1 - 0.1 12.3 6.0 0.21 11.3 6.0 1.6 1 0 0 1 1 1 0 RING-like zinc finger DUF1272 PF06906.11 EGC39962.1 - 0.48 10.5 7.1 0.94 9.6 7.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Zn_ribbon_17 PF17120.5 EGC39962.1 - 1.1 8.9 8.7 1.8 8.2 8.7 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-HC5HC2H PF13771.6 EGC39962.1 - 1.2 9.4 13.2 0.97 9.7 10.1 2.5 1 1 1 2 2 2 0 PHD-like zinc-binding domain NAD_binding_1 PF00175.21 EGC39962.1 - 5.6 7.7 8.7 22 5.7 8.7 2.0 1 0 0 1 1 1 0 Oxidoreductase NAD-binding domain zf-C3HC4_2 PF13923.6 EGC39963.1 - 1.4e-11 44.0 9.1 2.9e-11 43.0 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC39963.1 - 3.2e-11 42.9 9.5 5.5e-11 42.2 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39963.1 - 8e-10 38.9 8.9 1.5e-09 38.1 8.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC39963.1 - 1.6e-08 34.2 12.0 3.4e-08 33.2 12.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC39963.1 - 1.7e-08 34.3 10.2 3.3e-08 33.3 10.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39963.1 - 1.7e-06 28.0 1.8 1.7e-06 28.0 1.8 2.1 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC39963.1 - 4e-05 23.8 6.6 0.00013 22.1 6.6 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC39963.1 - 6.4e-05 23.0 8.6 0.00018 21.6 8.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC39963.1 - 0.0008 19.2 8.2 0.0022 17.8 8.1 1.7 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC39963.1 - 0.00095 18.9 6.3 0.00095 18.9 6.3 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_4 PF14570.6 EGC39963.1 - 0.0033 17.2 9.4 0.0091 15.8 9.4 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC39963.1 - 0.0072 16.3 3.6 0.025 14.6 3.6 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC39963.1 - 0.0075 16.4 6.9 0.017 15.2 6.9 1.6 1 0 0 1 1 1 1 zinc RING finger of MSL2 TFIIA PF03153.13 EGC39963.1 - 0.012 15.6 27.7 0.021 14.9 27.7 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-TFIIIC PF12660.7 EGC39963.1 - 0.21 11.6 9.8 0.079 12.9 5.7 2.4 2 0 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex Prok-E2_E PF14462.6 EGC39963.1 - 0.26 11.1 4.2 0.53 10.1 4.2 1.5 1 0 0 1 1 1 0 Prokaryotic E2 family E zf-RING_6 PF14835.6 EGC39963.1 - 0.81 9.6 4.8 1.7 8.6 4.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 EGC39963.1 - 1.8 8.7 9.4 6.3 7.0 0.1 2.8 2 1 0 2 2 2 0 FYVE zinc finger N6_N4_Mtase PF01555.18 EGC39963.1 - 1.9 8.2 8.8 0.18 11.5 1.2 2.4 2 1 0 2 2 2 0 DNA methylase DZR PF12773.7 EGC39963.1 - 2.9 8.0 7.0 7.8 6.6 7.0 1.7 1 0 0 1 1 1 0 Double zinc ribbon GW PF13457.6 EGC39963.1 - 3.2 8.4 7.1 10 6.8 0.1 2.6 2 1 0 2 2 2 0 GW (Gly-Tryp) dipeptide domain Beta_helix PF13229.6 EGC39964.1 - 0.0026 17.6 17.0 0.0026 17.6 17.0 5.9 3 1 3 6 6 6 2 Right handed beta helix region CCDC24 PF15669.5 EGC39964.1 - 0.25 11.2 6.1 0.45 10.3 6.1 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 24 family NCD3G PF07562.14 EGC39964.1 - 4.9 7.2 11.9 0.41 10.7 3.7 2.7 2 0 0 2 2 2 0 Nine Cysteines Domain of family 3 GPCR BK_channel_a PF03493.18 EGC39966.1 - 4.3e-19 68.5 0.0 1.4e-18 66.9 0.0 1.9 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.31 EGC39966.1 - 1.3e-15 57.3 23.1 1.3e-15 57.3 23.1 2.2 2 0 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.16 EGC39966.1 - 1.7e-10 40.7 5.0 1.7e-10 40.7 5.0 2.4 3 0 0 3 3 3 1 Ion channel TrkA_C PF02080.21 EGC39966.1 - 0.08 12.8 0.0 1.8 8.4 0.0 2.5 2 0 0 2 2 2 0 TrkA-C domain TFIIF_alpha PF05793.12 EGC39966.1 - 0.53 8.8 7.5 0.9 8.0 7.5 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Fig1 PF12351.8 EGC39966.1 - 1.2 9.0 5.2 3.2 7.7 0.9 2.6 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 Pkinase PF00069.25 EGC39967.1 - 2.1e-80 269.9 0.0 2.7e-80 269.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39967.1 - 1.2e-42 146.0 0.0 1.5e-42 145.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.14 EGC39967.1 - 3.1e-05 23.4 0.1 6.1e-05 22.5 0.1 1.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.6 EGC39967.1 - 0.0024 17.3 0.5 0.049 12.9 0.1 2.4 1 1 1 2 2 2 1 Kinase-like APH PF01636.23 EGC39967.1 - 0.1 12.5 0.1 2.1 8.2 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family UAA PF08449.11 EGC39968.1 - 2.8e-101 338.7 29.4 3.2e-101 338.5 29.4 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.20 EGC39968.1 - 4.1e-08 33.5 33.6 0.00017 21.8 13.7 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.16 EGC39968.1 - 1.6e-07 31.0 22.6 9.8e-07 28.4 22.6 1.9 1 1 0 1 1 1 1 Triose-phosphate Transporter family tRNA-synt_2 PF00152.20 EGC39969.1 - 4.5e-92 308.5 0.1 6.1e-92 308.0 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.15 EGC39969.1 - 1.6e-46 158.3 1.8 1.6e-46 158.3 1.8 1.8 2 0 0 2 2 2 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.25 EGC39969.1 - 4.4e-12 45.8 0.0 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.20 EGC39969.1 - 0.049 13.1 0.1 6.3 6.2 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) COPIIcoated_ERV PF07970.12 EGC39970.1 - 9.2e-86 287.2 0.1 9.2e-86 287.2 0.1 2.0 3 0 0 3 3 3 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.6 EGC39970.1 - 1.4e-32 111.9 2.3 2.3e-32 111.2 0.2 2.1 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PHB_depo_C PF06850.11 EGC39970.1 - 0.01 15.3 0.0 0.017 14.6 0.0 1.3 1 0 0 1 1 1 0 PHB de-polymerase C-terminus DUF1673 PF07895.11 EGC39970.1 - 0.19 11.4 1.6 1.7 8.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Kelch_6 PF13964.6 EGC39971.1 - 1.2e-18 66.6 5.4 3.5e-05 23.9 0.0 6.3 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.25 EGC39971.1 - 2.4e-17 62.3 2.8 2.4e-05 23.8 0.0 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.6 EGC39971.1 - 2.4e-11 43.5 0.7 0.00028 20.8 0.0 5.3 4 1 1 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.6 EGC39971.1 - 4.3e-11 42.8 0.0 0.046 14.0 0.0 5.2 4 0 0 4 4 4 3 Galactose oxidase, central domain zf-B_box PF00643.24 EGC39971.1 - 1.5e-08 34.6 10.6 1.5e-08 34.6 10.6 3.2 3 1 0 3 3 3 1 B-box zinc finger Kelch_2 PF07646.15 EGC39971.1 - 4.4e-06 26.4 2.3 0.11 12.5 0.2 4.1 4 0 0 4 4 3 2 Kelch motif zf-C3HC4 PF00097.25 EGC39971.1 - 0.00012 21.8 12.0 0.00012 21.8 12.0 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC39971.1 - 0.00021 21.4 10.9 0.00021 21.4 10.9 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING Kelch_5 PF13854.6 EGC39971.1 - 0.0004 20.3 1.6 0.011 15.7 0.0 3.6 4 0 0 4 4 4 1 Kelch motif zf-RING_5 PF14634.6 EGC39971.1 - 0.00054 19.9 8.6 0.00054 19.9 8.6 2.5 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_2 PF13639.6 EGC39971.1 - 0.0011 19.3 9.0 0.0011 19.3 9.0 2.6 2 0 0 2 2 1 1 Ring finger domain zf-RING_6 PF14835.6 EGC39971.1 - 0.002 18.0 4.1 0.002 18.0 4.1 1.8 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.6 EGC39971.1 - 0.0033 17.4 11.0 0.0033 17.4 11.0 2.8 2 0 0 2 2 2 1 RING-type zinc-finger DUF5074 PF16819.5 EGC39971.1 - 0.0071 16.4 5.0 1 9.4 0.3 3.9 2 1 1 3 3 3 1 Domain of unknown function (DUF5074) Osmo_CC PF08946.10 EGC39971.1 - 0.06 13.6 3.4 0.24 11.7 1.2 2.7 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF1664 PF07889.12 EGC39971.1 - 9.9 6.2 10.3 17 5.5 9.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Glyco_hydro_9 PF00759.19 EGC39972.1 - 8e-130 433.9 10.4 9.1e-130 433.8 10.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Orf78 PF06024.12 EGC39973.1 - 0.08 13.3 6.5 0.15 12.3 0.5 2.4 2 0 0 2 2 2 0 Orf78 (ac78) Secretin_N_2 PF07655.13 EGC39973.1 - 0.83 10.2 12.0 2 9.0 12.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Pkinase PF00069.25 EGC39974.1 - 2.9e-67 226.8 0.0 4e-67 226.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC39974.1 - 8.7e-49 166.1 0.0 1.3e-48 165.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.29 EGC39974.1 - 2.6e-18 66.4 0.2 5.7e-18 65.4 0.2 1.6 1 0 0 1 1 1 1 PH domain PBD PF00786.28 EGC39974.1 - 9.4e-15 54.7 0.1 2.6e-14 53.3 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain Pkinase_fungal PF17667.1 EGC39974.1 - 2.6e-06 26.5 0.0 5.2e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Fungal protein kinase Haspin_kinase PF12330.8 EGC39974.1 - 6.7e-05 22.0 2.3 0.0003 19.8 2.1 1.8 1 1 0 1 1 1 1 Haspin like kinase domain Kinase-like PF14531.6 EGC39974.1 - 0.0034 16.8 0.1 0.017 14.5 0.0 1.9 1 1 0 2 2 2 1 Kinase-like PH_17 PF18012.1 EGC39974.1 - 0.0042 16.8 0.0 0.0085 15.8 0.0 1.5 1 0 0 1 1 1 1 PH domain DUF1491 PF07372.12 EGC39974.1 - 0.028 14.8 0.0 0.1 12.9 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1491) APH PF01636.23 EGC39974.1 - 0.23 11.3 0.0 0.63 9.9 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family PH_11 PF15413.6 EGC39974.1 - 0.26 11.7 6.8 1.2 9.6 0.7 3.0 2 1 1 3 3 3 0 Pleckstrin homology domain COX1 PF00115.20 EGC39975.1 - 0.43 9.4 11.9 1.3 7.8 2.1 2.3 2 1 0 2 2 2 0 Cytochrome C and Quinol oxidase polypeptide I Striatin PF08232.12 EGC39976.1 - 0.55 10.8 3.1 0.56 10.8 0.2 2.3 2 0 0 2 2 2 0 Striatin family ABC_tran PF00005.27 EGC39977.1 - 3.5e-44 150.6 0.7 1.3e-21 77.6 0.0 3.3 3 1 0 3 3 3 2 ABC transporter ABC_tran_Xtn PF12848.7 EGC39977.1 - 7.1e-20 70.8 13.1 7.1e-20 70.8 13.1 3.6 4 0 0 4 4 3 1 ABC transporter AAA_21 PF13304.6 EGC39977.1 - 1.9e-10 41.0 8.9 0.0059 16.4 0.5 4.9 5 0 0 5 5 5 4 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC39977.1 - 5.7e-07 29.2 6.8 0.0069 15.9 0.1 4.3 3 2 0 3 3 3 2 RecF/RecN/SMC N terminal domain RsgA_GTPase PF03193.16 EGC39977.1 - 1.4e-06 28.4 0.1 0.086 12.7 0.0 2.8 2 0 0 2 2 2 2 RsgA GTPase AAA_22 PF13401.6 EGC39977.1 - 3.9e-06 27.2 0.0 0.061 13.6 0.0 2.9 2 2 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.23 EGC39977.1 - 4.8e-06 26.6 1.5 0.061 13.4 0.0 3.8 4 0 0 4 4 4 2 50S ribosome-binding GTPase NB-ARC PF00931.22 EGC39977.1 - 1.4e-05 24.4 0.1 0.096 11.8 0.0 2.5 2 0 0 2 2 2 2 NB-ARC domain AAA_29 PF13555.6 EGC39977.1 - 2.7e-05 23.8 0.7 0.081 12.7 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_15 PF13175.6 EGC39977.1 - 6.3e-05 22.8 12.0 0.083 12.6 0.2 4.2 3 1 1 4 4 4 3 AAA ATPase domain AAA_33 PF13671.6 EGC39977.1 - 0.00035 20.8 0.3 1.5 9.0 0.0 3.3 3 0 0 3 3 3 1 AAA domain RNA_helicase PF00910.22 EGC39977.1 - 0.00048 20.5 0.0 1.6 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_16 PF13191.6 EGC39977.1 - 0.0005 20.5 0.0 0.77 10.1 0.0 2.6 2 0 0 2 2 2 2 AAA ATPase domain NACHT PF05729.12 EGC39977.1 - 0.00055 19.9 0.3 0.3 11.0 0.0 2.9 3 0 0 3 3 3 1 NACHT domain AAA_14 PF13173.6 EGC39977.1 - 0.0027 17.7 0.1 3 7.9 0.0 3.2 4 0 0 4 4 2 1 AAA domain AAA_24 PF13479.6 EGC39977.1 - 0.0045 16.7 1.6 2.3 7.9 0.0 3.0 3 0 0 3 3 3 2 AAA domain NTPase_1 PF03266.15 EGC39977.1 - 0.0051 16.7 0.0 2.1 8.3 0.0 2.7 2 0 0 2 2 2 1 NTPase AAA_28 PF13521.6 EGC39977.1 - 0.008 16.4 0.1 3.9 7.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_7 PF12775.7 EGC39977.1 - 0.008 15.7 0.7 4.9 6.6 0.2 2.8 2 1 1 3 3 3 1 P-loop containing dynein motor region SRP54 PF00448.22 EGC39977.1 - 0.013 15.1 0.1 6.8 6.3 0.0 2.6 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain MeaB PF03308.16 EGC39977.1 - 0.021 13.8 2.4 1.9 7.4 0.0 2.8 3 0 0 3 3 3 0 Methylmalonyl Co-A mutase-associated GTPase MeaB DUF5567 PF17722.1 EGC39977.1 - 0.025 14.5 5.3 0.046 13.6 5.3 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5567) Glyco_hydro_1 PF00232.18 EGC39977.1 - 0.027 12.9 0.2 0.05 12.0 0.2 1.4 1 0 0 1 1 1 0 Glycosyl hydrolase family 1 Roc PF08477.13 EGC39977.1 - 0.045 14.0 3.1 2.3 8.5 0.0 2.8 3 0 0 3 3 2 0 Ras of Complex, Roc, domain of DAPkinase AAA PF00004.29 EGC39977.1 - 0.062 13.7 2.9 11 6.4 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.6 EGC39977.1 - 0.11 12.2 0.0 2.3 7.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.6 EGC39977.1 - 0.3 11.6 3.3 3.4 8.2 0.1 3.5 3 1 0 3 3 3 0 AAA domain DUF87 PF01935.17 EGC39977.1 - 1.2 9.2 7.7 15 5.6 0.0 3.5 3 0 0 3 3 3 0 Helicase HerA, central domain RecQ_Zn_bind PF16124.5 EGC39977.1 - 1.4 9.7 4.8 13 6.6 0.0 2.8 2 1 1 3 3 3 0 RecQ zinc-binding Arf PF00025.21 EGC39977.1 - 1.8 8.0 5.7 10 5.6 0.0 3.1 3 0 0 3 3 3 0 ADP-ribosylation factor family PAP2 PF01569.21 EGC39978.1 - 1.1e-08 34.9 3.2 3.6e-08 33.3 3.2 2.0 1 0 0 1 1 1 1 PAP2 superfamily Peptidase_C15 PF01470.17 EGC39979.1 - 4.5e-12 46.6 0.0 1.3e-11 45.1 0.0 1.6 1 1 0 1 1 1 1 Pyroglutamyl peptidase PRESAN PF09687.10 EGC39979.1 - 0.016 15.8 7.2 0.026 15.1 6.8 1.8 1 1 0 1 1 1 0 Plasmodium RESA N-terminal GDP_Man_Dehyd PF16363.5 EGC39981.1 - 4.1e-160 532.7 0.0 4.6e-160 532.5 0.0 1.0 1 0 0 1 1 1 1 GDP-mannose 4,6 dehydratase Epimerase PF01370.21 EGC39981.1 - 3.7e-74 249.2 0.1 4.6e-74 248.9 0.1 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.17 EGC39981.1 - 0.0033 16.6 0.0 0.0054 15.9 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.15 EGC39981.1 - 0.039 13.1 0.0 0.066 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TAA-Trp-ring PF15401.6 EGC39981.1 - 0.082 13.4 0.1 0.17 12.3 0.1 1.5 1 0 0 1 1 1 0 Tryptophan-ring motif of head of Trimeric autotransporter adhesin Peptidase_M41 PF01434.18 EGC39982.1 - 7.1e-59 198.9 2.7 7.1e-59 198.9 2.7 3.2 2 1 1 3 3 2 1 Peptidase family M41 AAA PF00004.29 EGC39982.1 - 1.6e-42 145.0 0.0 1.6e-42 145.0 0.0 3.7 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC39982.1 - 1.4e-09 37.6 0.0 5.1e-09 35.8 0.0 2.0 2 0 0 2 2 2 1 AAA+ lid domain AAA_5 PF07728.14 EGC39982.1 - 3.3e-05 23.9 0.0 3.3e-05 23.9 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.12 EGC39982.1 - 0.00051 19.8 0.0 0.0021 17.8 0.0 2.1 1 1 0 1 1 1 1 Holliday junction DNA helicase RuvB P-loop domain AAA_33 PF13671.6 EGC39982.1 - 0.0025 18.0 0.0 0.0025 18.0 0.0 3.6 3 2 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGC39982.1 - 0.0047 17.5 0.0 0.0047 17.5 0.0 3.3 2 1 3 5 5 5 1 AAA domain AAA_16 PF13191.6 EGC39982.1 - 0.0048 17.3 0.2 0.0048 17.3 0.2 4.2 2 2 1 3 3 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC39982.1 - 0.0066 16.7 0.1 0.0066 16.7 0.1 4.2 2 2 0 3 3 2 1 AAA domain IstB_IS21 PF01695.17 EGC39982.1 - 0.012 15.4 0.0 0.012 15.4 0.0 2.6 2 0 0 2 2 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.21 EGC39982.1 - 0.017 14.5 0.2 0.017 14.5 0.2 2.8 2 1 1 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.6 EGC39982.1 - 0.028 14.1 0.0 0.028 14.1 0.0 2.9 2 1 0 2 2 1 0 AAA domain AAA_25 PF13481.6 EGC39982.1 - 0.056 13.0 1.2 0.13 11.8 0.0 2.2 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.6 EGC39982.1 - 0.11 12.7 0.0 0.11 12.7 0.0 3.5 2 1 0 2 2 1 0 AAA domain RNA_helicase PF00910.22 EGC39982.1 - 0.17 12.3 0.0 0.17 12.3 0.0 2.9 2 1 0 3 3 2 0 RNA helicase PAT1 PF09770.9 EGC39982.1 - 0.72 8.1 49.2 0.9 7.7 49.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LIM PF00412.22 EGC39983.1 - 4e-45 151.8 108.0 4.8e-11 42.7 4.6 10.0 7 2 2 9 9 9 8 LIM domain CH PF00307.31 EGC39983.1 - 2.3e-19 69.6 0.1 7.2e-19 68.0 0.1 1.9 1 0 0 1 1 1 1 Calponin homology (CH) domain CDC24 PF06395.11 EGC39983.1 - 0.01 16.1 0.1 0.024 14.9 0.1 1.6 1 0 0 1 1 1 0 CDC24 Calponin CAMSAP_CH PF11971.8 EGC39983.1 - 0.014 15.2 0.0 0.057 13.2 0.0 2.0 1 0 0 1 1 1 0 CAMSAP CH domain Presenilin PF01080.17 EGC39984.1 - 4.1 6.1 20.3 5.5 5.7 20.3 1.2 1 0 0 1 1 1 0 Presenilin SWI-SNF_Ssr4 PF08549.10 EGC39984.1 - 6.6 5.2 23.1 7.9 5.0 23.1 1.0 1 0 0 1 1 1 0 Fungal domain of unknown function (DUF1750) zf-C3HC4_2 PF13923.6 EGC39985.1 - 1.1e-10 41.2 10.1 1.8e-10 40.4 10.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39985.1 - 1.1e-09 38.4 10.2 1.8e-09 37.7 10.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC39985.1 - 1.6e-09 37.4 10.0 2.5e-09 36.8 10.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC39985.1 - 3e-08 33.5 11.0 5.6e-08 32.6 11.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.25 EGC39985.1 - 2.1e-07 30.7 13.1 3.9e-07 29.8 13.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC39985.1 - 9.2e-07 28.8 4.8 3.7e-06 26.9 4.8 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC39985.1 - 8.9e-05 22.7 7.0 0.00024 21.3 7.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC39985.1 - 0.00015 21.8 9.2 0.00031 20.8 8.7 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC39985.1 - 0.00046 20.0 10.5 0.0015 18.3 10.6 1.8 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_10 PF16685.5 EGC39985.1 - 0.00082 19.5 5.5 0.0016 18.5 5.5 1.5 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC39985.1 - 0.0036 17.0 8.3 0.0087 15.8 8.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC39985.1 - 0.0095 16.0 3.9 0.02 14.9 3.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-TFIIIC PF12660.7 EGC39985.1 - 0.011 15.7 3.6 0.037 14.0 3.6 1.9 1 0 0 1 1 1 0 Putative zinc-finger of transcription factor IIIC complex TFIIA PF03153.13 EGC39985.1 - 0.042 13.9 23.6 0.065 13.2 23.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_6 PF14835.6 EGC39985.1 - 0.23 11.3 4.1 0.48 10.3 4.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_11 PF17123.5 EGC39985.1 - 0.37 10.6 13.7 0.035 13.8 8.6 2.0 2 0 0 2 2 2 0 RING-like zinc finger V_ATPase_I PF01496.19 EGC39985.1 - 2.6 5.9 12.7 29 2.4 12.1 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family FYVE PF01363.21 EGC39985.1 - 7.2 6.8 10.1 15 5.8 0.2 3.0 2 1 1 3 3 3 0 FYVE zinc finger Methyltransf_10 PF05971.12 EGC39986.1 - 4.7e-67 226.4 0.4 8.9e-66 222.2 0.4 2.1 1 1 0 1 1 1 1 RNA methyltransferase MTS PF05175.14 EGC39986.1 - 3.4e-07 30.0 0.0 2.2e-06 27.3 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.6 EGC39986.1 - 1.1e-05 25.3 0.6 9.8e-05 22.2 0.1 2.2 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.13 EGC39986.1 - 1.5e-05 24.6 0.1 3.5e-05 23.4 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) HEPN_AbiA_CTD PF18732.1 EGC39986.1 - 0.0057 16.6 5.1 0.014 15.3 5.1 1.7 1 0 0 1 1 1 1 HEPN like, Abia C-terminal domain N6-adenineMlase PF10237.9 EGC39986.1 - 0.0087 15.9 0.1 0.022 14.6 0.1 1.7 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Met_10 PF02475.16 EGC39986.1 - 0.031 14.0 0.0 0.05 13.3 0.0 1.5 1 0 0 1 1 1 0 Met-10+ like-protein SAP30_Sin3_bdg PF13867.6 EGC39986.1 - 0.081 13.3 0.0 0.21 12.0 0.0 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Methyltransf_12 PF08242.12 EGC39986.1 - 0.36 11.6 2.3 1.7 9.5 0.0 2.8 2 1 0 2 2 2 0 Methyltransferase domain DsrD PF08679.11 EGC39986.1 - 2.9 8.2 7.6 2.9 8.2 0.4 3.5 4 0 0 4 4 4 0 Dissimilatory sulfite reductase D (DsrD) zf-CCHC_6 PF15288.6 EGC39987.1 - 0.00075 19.3 0.9 0.0017 18.2 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.23 EGC39987.1 - 1.6 8.9 4.0 0.33 11.1 0.5 1.7 2 0 0 2 2 2 0 Zinc knuckle ketoacyl-synt PF00109.26 EGC39988.1 - 1.6e-78 263.8 0.0 2.8e-78 263.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC39988.1 - 1.5e-49 169.2 0.0 2.5e-49 168.5 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC39988.1 - 1.6e-40 137.8 0.0 3.8e-40 136.6 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC39988.1 - 5e-32 111.3 0.0 9e-32 110.4 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.6 EGC39988.1 - 1.7e-23 83.3 0.0 2.7e-23 82.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC39988.1 - 9e-20 71.2 0.3 2.8e-19 69.6 0.3 1.9 1 0 0 1 1 1 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC39988.1 - 3.4e-11 44.3 0.0 1.3e-10 42.5 0.0 2.1 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.25 EGC39988.1 - 4.3e-09 36.6 0.1 1.4e-08 34.9 0.1 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.23 EGC39988.1 - 3.5e-08 33.2 0.1 1.1e-07 31.5 0.1 1.8 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.12 EGC39988.1 - 4.6e-05 23.3 0.0 0.00016 21.5 0.0 1.9 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.12 EGC39988.1 - 0.013 16.2 0.1 0.098 13.4 0.1 2.7 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGC39988.1 - 0.06 13.2 0.0 0.18 11.6 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain E2_bind PF08825.10 EGC39988.1 - 0.062 13.5 1.8 0.19 11.9 0.5 2.6 2 0 0 2 2 2 0 E2 binding domain Spo0A_C PF08769.11 EGC39988.1 - 0.2 11.7 5.2 0.41 10.8 0.8 3.6 2 1 1 3 3 3 0 Sporulation initiation factor Spo0A C terminal Syndecan PF01034.20 EGC39989.1 - 0.011 15.6 0.0 0.058 13.3 0.0 2.2 1 0 0 1 1 1 0 Syndecan domain Tox-SGS PF15651.6 EGC39989.1 - 0.083 13.1 3.0 5.5 7.3 0.1 4.0 3 0 0 3 3 3 0 Salivary glad secreted protein domain toxin Y_Y_Y PF07495.13 EGC39989.1 - 0.54 10.3 13.2 0.34 10.9 0.2 4.9 5 0 0 5 5 5 0 Y_Y_Y domain SBF_like PF13593.6 EGC39990.1 - 4.3e-05 23.0 1.7 7.8e-05 22.1 1.7 1.4 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) FmiP_Thoc5 PF09766.9 EGC39991.1 - 2.4e-45 155.4 18.8 3.3e-24 85.9 11.1 2.5 1 1 2 3 3 3 2 Fms-interacting protein/Thoc5 Glycophorin_A PF01102.18 EGC39992.1 - 0.2 11.9 1.4 0.38 11.0 0.0 2.1 2 1 0 2 2 2 0 Glycophorin A CAC1F_C PF16885.5 EGC39992.1 - 0.38 10.4 7.7 1.8 8.2 0.7 2.1 2 0 0 2 2 2 0 Voltage-gated calcium channel subunit alpha, C-term 60KD_IMP PF02096.20 EGC39992.1 - 0.46 10.4 5.8 0.9 9.4 5.8 1.5 1 0 0 1 1 1 0 60Kd inner membrane protein Peroxin-13_N PF04088.13 EGC39992.1 - 1.2 9.4 6.0 1.2 9.4 1.1 2.5 2 0 0 2 2 2 0 Peroxin 13, N-terminal region AAA_11 PF13086.6 EGC39992.1 - 2.1 8.0 9.0 2.1 8.0 2.7 2.2 2 0 0 2 2 2 0 AAA domain Pex14_N PF04695.13 EGC39992.1 - 4 8.1 12.6 0.71 10.5 3.5 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Zip PF02535.22 EGC39992.1 - 5.3 6.2 9.2 1.9 7.6 0.3 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter V-SNARE_C PF12352.8 EGC39993.1 - 4.9e-17 62.0 7.3 2.2e-16 59.9 3.2 2.6 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.13 EGC39993.1 - 1.2e-08 34.8 0.6 1.2e-08 34.8 0.6 2.7 2 1 1 3 3 3 1 Sec20 DUF325 PF03804.13 EGC39993.1 - 0.018 15.0 0.1 0.05 13.6 0.0 1.8 2 0 0 2 2 2 0 Viral proteins of unknown function E2F_TDP PF02319.20 EGC39993.1 - 0.19 11.8 2.5 0.49 10.5 2.5 1.8 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain Coatomer_E PF04733.14 EGC39994.1 - 5.7e-81 272.1 4.1 6.6e-81 271.9 4.1 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.6 EGC39994.1 - 1.3e-08 35.2 3.7 0.00011 22.7 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat PPR_2 PF13041.6 EGC39994.1 - 2.4e-06 27.6 1.5 0.17 12.1 0.0 4.5 5 0 0 5 5 5 2 PPR repeat family ANAPC3 PF12895.7 EGC39994.1 - 0.00017 21.7 3.5 1.8 8.9 0.0 3.4 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 PPR PF01535.20 EGC39994.1 - 0.00065 19.8 6.4 1.6 9.1 0.1 5.1 6 0 0 6 6 6 2 PPR repeat TPR_1 PF00515.28 EGC39994.1 - 0.00069 19.3 4.4 2.2 8.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC39994.1 - 0.0086 16.3 1.2 1.4 9.3 0.1 4.3 3 1 3 6 6 6 2 Tetratricopeptide repeat TPR_17 PF13431.6 EGC39994.1 - 0.06 13.8 4.4 18 6.0 0.0 4.3 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_14 PF13428.6 EGC39994.1 - 0.1 13.4 2.7 24 6.1 0.2 4.4 2 1 3 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.17 EGC39994.1 - 0.12 12.5 9.5 1.2 9.4 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat Varsurf_PPLC PF03490.13 EGC39995.1 - 4.2e-05 23.4 0.0 0.0001 22.1 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C PI-PLC-X PF00388.19 EGC39995.1 - 0.0012 18.4 0.0 0.0025 17.4 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain HNF-1B_C PF04812.13 EGC39995.1 - 0.17 11.7 0.0 0.31 10.8 0.0 1.3 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus LMWPc PF01451.21 EGC39996.1 - 9.5e-33 113.6 0.0 1.1e-31 110.2 0.0 1.9 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase zf-C3HC4_2 PF13923.6 EGC39997.1 - 2.1e-11 43.5 9.0 4.3e-11 42.5 9.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC39997.1 - 1.5e-10 40.8 9.5 2.3e-10 40.1 9.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC39997.1 - 6.2e-10 39.2 8.8 1.1e-09 38.5 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC39997.1 - 2.9e-08 33.5 12.0 5.6e-08 32.5 12.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.6 EGC39997.1 - 4.8e-08 32.8 10.1 9.5e-08 31.9 10.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC39997.1 - 5.8e-06 26.2 5.7 3.5e-05 23.7 5.7 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC39997.1 - 2.9e-05 24.2 6.5 0.0001 22.5 6.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_4 PF15227.6 EGC39997.1 - 3e-05 24.1 7.6 8e-05 22.7 7.5 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC39997.1 - 0.00089 19.1 7.9 0.0025 17.6 7.9 1.8 1 1 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_11 PF17123.5 EGC39997.1 - 0.0011 18.6 6.2 0.0011 18.6 6.2 2.0 2 0 0 2 2 2 1 RING-like zinc finger zf-RING_10 PF16685.5 EGC39997.1 - 0.003 17.7 5.8 0.0068 16.5 5.8 1.7 1 0 0 1 1 1 1 zinc RING finger of MSL2 zf-RING_4 PF14570.6 EGC39997.1 - 0.0078 16.0 9.6 0.022 14.6 9.6 1.8 1 1 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-TFIIIC PF12660.7 EGC39997.1 - 0.0086 16.0 4.9 0.034 14.1 4.9 2.0 1 0 0 1 1 1 1 Putative zinc-finger of transcription factor IIIC complex zf-ANAPC11 PF12861.7 EGC39997.1 - 0.02 14.9 3.4 0.02 14.9 3.4 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TFIIA PF03153.13 EGC39997.1 - 0.038 14.0 32.2 0.065 13.2 32.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Prok-E2_E PF14462.6 EGC39997.1 - 0.1 12.4 3.4 0.22 11.3 3.4 1.6 1 0 0 1 1 1 0 Prokaryotic E2 family E zf-RING_6 PF14835.6 EGC39997.1 - 0.75 9.7 4.9 1.5 8.7 4.9 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein FYVE PF01363.21 EGC39997.1 - 2.7 8.2 9.8 5.7 7.2 0.2 2.9 2 1 0 2 2 2 0 FYVE zinc finger DZR PF12773.7 EGC39997.1 - 6.7 6.8 8.7 22 5.2 8.7 1.8 1 1 0 1 1 1 0 Double zinc ribbon STATa_Ig PF18214.1 EGC39999.1 - 3.6e-42 143.2 4.1 1.1e-41 141.7 4.1 1.9 1 0 0 1 1 1 1 STATa Immunoglobulin-like domain EF-hand_12 PF17901.1 EGC39999.1 - 4.5e-42 142.4 2.1 4.5e-42 142.4 2.1 2.5 2 1 1 3 3 3 1 EF-hand fold domain SH2 PF00017.24 EGC39999.1 - 1.7e-09 37.6 0.0 1.8e-08 34.4 0.0 2.6 2 0 0 2 2 2 1 SH2 domain Dict-STAT-coil PF09267.10 EGC39999.1 - 4.6e-06 27.0 3.1 4.6e-06 27.0 3.1 3.7 3 0 0 3 3 3 1 Dictyostelium STAT, coiled coil Abhydrolase_2 PF02230.16 EGC40000.1 - 1.1e-55 188.8 0.1 1.2e-55 188.6 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase FSH1 PF03959.13 EGC40000.1 - 3.8e-06 26.7 0.0 9.4e-06 25.4 0.0 1.5 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.7 EGC40000.1 - 0.0037 17.9 0.0 0.0045 17.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.8 EGC40000.1 - 0.004 16.5 0.0 0.21 10.8 0.0 2.5 2 1 1 3 3 3 1 Serine aminopeptidase, S33 Peptidase_S9 PF00326.21 EGC40000.1 - 0.009 15.5 0.0 0.035 13.6 0.0 2.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.18 EGC40000.1 - 0.042 13.4 0.0 0.063 12.8 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family Choline_kinase PF01633.20 EGC40001.1 - 6.4e-65 218.7 0.6 6.4e-65 218.7 0.6 1.6 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.23 EGC40001.1 - 9.1e-08 32.3 0.0 1.2e-07 32.0 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.20 EGC40001.1 - 0.0012 18.2 0.5 0.0026 17.1 0.5 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Pkinase PF00069.25 EGC40001.1 - 0.045 13.1 0.3 0.096 12.0 0.3 1.5 1 0 0 1 1 1 0 Protein kinase domain EamA PF00892.20 EGC40002.1 - 3.8e-34 117.8 37.1 1.7e-19 70.3 12.6 2.1 2 0 0 2 2 2 2 EamA-like transporter family MgtC PF02308.16 EGC40002.1 - 0.018 15.4 4.6 0.029 14.7 3.2 2.2 1 1 0 1 1 1 0 MgtC family Syndecan PF01034.20 EGC40002.1 - 0.071 13.0 0.1 0.071 13.0 0.1 2.8 3 0 0 3 3 3 0 Syndecan domain DUF2065 PF09838.9 EGC40002.1 - 0.49 10.4 3.0 4.9 7.3 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Coa1 PF08695.10 EGC40003.1 - 0.012 15.4 0.0 1.4 8.7 0.0 2.4 2 0 0 2 2 2 0 Cytochrome oxidase complex assembly protein 1 COLFI PF01410.18 EGC40003.1 - 0.12 11.7 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Methyltransf_16 PF10294.9 EGC40004.1 - 8.9e-22 77.6 0.0 1.2e-21 77.2 0.0 1.1 1 0 0 1 1 1 1 Lysine methyltransferase Methyltransf_23 PF13489.6 EGC40004.1 - 1.5e-07 31.4 0.0 2.9e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.14 EGC40004.1 - 3.9e-06 26.4 0.3 3.9e-06 26.4 0.3 1.8 1 1 1 2 2 2 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.6 EGC40004.1 - 7.9e-06 25.7 0.0 1.5e-05 24.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC40004.1 - 4.3e-05 24.2 0.1 0.00034 21.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC40004.1 - 0.0012 19.5 0.0 0.002 18.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC40004.1 - 0.0079 16.8 0.0 0.013 16.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.14 EGC40004.1 - 0.017 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain PrmA PF06325.13 EGC40004.1 - 0.03 13.7 0.2 0.047 13.1 0.0 1.4 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) NodS PF05401.11 EGC40004.1 - 0.17 11.5 0.0 0.23 11.0 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) SF3b10 PF07189.11 EGC40005.1 - 3.8e-35 119.8 0.0 4.4e-35 119.7 0.0 1.1 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Mito_carr PF00153.27 EGC40006.1 - 4.9e-62 205.9 6.8 1.6e-20 72.8 0.5 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Form-deh_trans PF09163.11 EGC40006.1 - 1.2 9.0 3.6 1.1 9.0 0.1 2.6 3 0 0 3 3 3 0 Formate dehydrogenase N, transmembrane RRM_1 PF00076.22 EGC40007.1 - 2.4e-24 84.9 0.6 2.1e-14 53.1 0.1 3.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.6 EGC40007.1 - 0.0012 18.8 0.0 1.1 9.3 0.0 2.5 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif RRM_occluded PF16842.5 EGC40007.1 - 0.0061 16.4 0.0 0.38 10.7 0.0 2.5 2 0 0 2 2 2 1 Occluded RNA-recognition motif FNIP PF05725.12 EGC40009.1 - 5.1e-17 61.8 72.8 1.5e-08 34.6 1.1 12.5 10 3 2 12 12 12 8 FNIP Repeat ubiquitin PF00240.23 EGC40010.1 - 5.4e-22 77.3 0.5 9.1e-22 76.6 0.5 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.8 EGC40010.1 - 4.6e-08 32.8 1.3 8.8e-08 31.9 1.3 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.31 EGC40010.1 - 5.8e-06 26.1 0.1 5.8e-06 26.1 0.1 2.9 3 0 0 3 3 2 1 UBA/TS-N domain DUF2407 PF10302.9 EGC40010.1 - 0.00019 21.9 0.2 0.00073 20.1 0.0 2.0 2 0 0 2 2 2 1 DUF2407 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC40010.1 - 0.00027 21.2 0.4 0.00052 20.3 0.4 1.4 1 0 0 1 1 1 1 Ubiquitin-like domain LPD22 PF18834.1 EGC40010.1 - 0.0011 19.2 1.4 0.068 13.4 0.3 3.0 3 0 0 3 3 3 1 Large polyvalent protein associated domain 22 Rad60-SLD_2 PF13881.6 EGC40010.1 - 0.011 15.9 0.0 0.023 14.8 0.0 1.5 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like STI1 PF17830.1 EGC40010.1 - 0.017 15.1 52.4 0.019 14.9 6.3 5.4 2 2 2 4 4 4 0 STI1 domain HOIP-UBA PF16678.5 EGC40010.1 - 0.02 14.9 0.0 0.069 13.2 0.0 1.9 2 0 0 2 2 2 0 HOIP UBA domain pair Ubiquitin_2 PF14560.6 EGC40010.1 - 0.13 12.8 0.3 0.44 11.0 0.3 2.0 1 1 0 1 1 1 0 Ubiquitin-like domain Keratin_2_head PF16208.5 EGC40010.1 - 0.17 12.0 36.9 0.51 10.5 3.8 2.2 2 0 0 2 2 2 0 Keratin type II head HECW1_helix PF18436.1 EGC40010.1 - 0.6 10.3 8.2 11 6.2 0.4 3.5 2 1 1 3 3 3 0 Helical box domain of E3 ubiquitin-protein ligase HECW1 Mod_r PF07200.13 EGC40010.1 - 2.2 8.4 5.1 3.2 7.8 0.7 2.8 2 1 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Com_YlbF PF06133.11 EGC40010.1 - 6.3 7.5 16.8 2.3 8.9 1.5 3.8 2 1 0 2 2 2 0 Control of competence regulator ComK, YlbF/YmcA Yippee-Mis18 PF03226.14 EGC40011.1 - 4.7e-17 62.1 0.6 5.7e-17 61.9 0.6 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.8 EGC40011.1 - 0.033 14.4 1.3 0.046 14.0 1.3 1.3 1 0 0 1 1 1 0 C-terminal domain of RIG-I CDKN3 PF05706.12 EGC40012.1 - 2e-06 27.6 0.0 3.6e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.6 EGC40012.1 - 5.1e-05 23.4 0.0 9.7e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.13 EGC40012.1 - 0.00019 21.1 0.1 0.00041 20.0 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.20 EGC40012.1 - 0.0003 20.6 0.0 0.00099 18.9 0.0 1.7 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.27 EGC40012.1 - 0.0026 17.3 0.0 0.0041 16.7 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.6 EGC40012.1 - 0.022 14.9 0.2 0.076 13.1 0.0 1.9 2 0 0 2 2 2 0 Inositol hexakisphosphate DnaJ-X PF14308.6 EGC40013.1 - 1.1e-29 103.4 2.6 1.1e-29 103.4 2.6 2.2 2 1 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.31 EGC40013.1 - 9.9e-27 92.9 6.9 2.7e-26 91.5 6.9 1.8 1 0 0 1 1 1 1 DnaJ domain Armet PF10208.9 EGC40013.1 - 0.001 19.0 2.5 0.018 14.9 0.0 3.0 3 0 0 3 3 3 1 Degradation arginine-rich protein for mis-folding PTB PF08416.13 EGC40013.1 - 0.013 15.6 0.0 0.47 10.6 0.0 2.3 2 0 0 2 2 2 0 Phosphotyrosine-binding domain ArenaCapSnatch PF17296.2 EGC40013.1 - 0.031 13.7 0.2 5 6.5 0.0 2.4 2 0 0 2 2 2 0 Arenavirus cap snatching domain Rod_C PF10493.9 EGC40013.1 - 0.15 10.4 7.3 0.011 14.2 2.0 1.6 2 0 0 2 2 2 0 Rough deal protein C-terminal region DUF87 PF01935.17 EGC40013.1 - 1.5 8.9 5.8 13 5.8 1.8 2.7 1 1 1 2 2 2 0 Helicase HerA, central domain DUF349 PF03993.12 EGC40013.1 - 2.4 8.5 6.0 14 6.0 0.2 3.3 3 0 0 3 3 3 0 Domain of Unknown Function (DUF349) CD36 PF01130.21 EGC40014.1 - 6.1e-52 176.7 18.3 7.7e-31 107.1 3.9 2.3 2 1 0 2 2 2 2 CD36 family DUF3185 PF11381.8 EGC40014.1 - 0.0022 18.0 4.7 0.63 10.1 0.4 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF3185) Phage_holin_3_6 PF07332.11 EGC40014.1 - 0.99 9.5 6.3 0.41 10.7 0.2 2.3 2 0 0 2 2 2 0 Putative Actinobacterial Holin-X, holin superfamily III Acetyltransf_3 PF13302.7 EGC40015.1 - 3.2e-16 60.3 0.0 4.1e-16 59.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.25 EGC40015.1 - 0.00012 22.3 0.0 0.00016 21.9 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF4823 PF16105.5 EGC40015.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4823) DUF4175 PF13779.6 EGC40016.1 - 1.9 6.3 21.6 4.5 5.1 21.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) HCO3_cotransp PF00955.21 EGC40016.1 - 4.6 6.0 10.1 12 4.6 10.1 1.7 1 0 0 1 1 1 0 HCO3- transporter family CD36 PF01130.21 EGC40017.1 - 2.7e-52 177.9 17.2 1.3e-30 106.4 2.4 2.3 2 0 0 2 2 2 2 CD36 family DUF3899 PF13038.6 EGC40017.1 - 0.064 13.8 5.7 0.17 12.4 0.1 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF3899) DUF3439 PF11921.8 EGC40019.1 - 0.0035 17.3 1.8 0.0067 16.4 1.8 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC40019.1 - 0.18 11.8 8.8 0.36 10.8 8.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Homeodomain PF00046.29 EGC40020.1 - 1.2e-16 60.3 3.4 3e-16 59.0 3.4 1.7 1 0 0 1 1 1 1 Homeodomain Homeobox_KN PF05920.11 EGC40020.1 - 2.4e-07 30.5 1.4 8.2e-07 28.8 0.0 2.6 2 1 1 3 3 3 1 Homeobox KN domain Homez PF11569.8 EGC40020.1 - 0.099 12.1 0.1 0.23 11.0 0.1 1.6 1 0 0 1 1 1 0 Homeodomain leucine-zipper encoding, Homez ER PF01133.17 EGC40021.1 - 1.8e-41 140.1 2.7 1.9e-41 140.0 2.7 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary F5_F8_type_C PF00754.25 EGC40022.1 - 3.6e-21 75.6 0.9 5e-21 75.1 0.9 1.2 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.10 EGC40022.1 - 1.4e-15 57.3 0.1 3.5e-15 55.9 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain DEAD PF00270.29 EGC40023.1 - 6e-44 149.9 0.1 1.1e-43 149.1 0.1 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC40023.1 - 2.1e-31 108.5 2.1 4.1e-29 101.2 0.1 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGC40023.1 - 2.4e-11 44.0 0.1 4.4e-11 43.1 0.1 1.5 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.23 EGC40023.1 - 0.00023 20.0 0.0 0.00037 19.3 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain AAA_19 PF13245.6 EGC40023.1 - 0.0044 17.4 0.0 0.0082 16.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC40023.1 - 0.0052 16.5 0.0 0.016 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.6 EGC40023.1 - 0.017 15.4 0.2 0.14 12.4 0.2 2.2 1 1 0 1 1 1 0 AAA domain PTA_PTB PF01515.19 EGC40023.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.4 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase Flavi_DEAD PF07652.14 EGC40023.1 - 0.021 14.8 0.1 0.14 12.2 0.1 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain SWI2_SNF2 PF18766.1 EGC40023.1 - 0.059 13.0 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 SWI2/SNF2 ATPase Sigma54_activ_2 PF14532.6 EGC40023.1 - 0.074 13.2 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Myosin_head PF00063.21 EGC40024.1 - 1.5e-222 740.6 0.1 7.5e-222 738.3 0.1 1.8 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.6 EGC40024.1 - 0.0011 19.4 0.0 0.0051 17.2 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.6 EGC40024.1 - 0.014 15.7 0.0 0.058 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.7 EGC40024.1 - 0.018 13.9 0.0 0.041 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA-like domain Sigma54_activat PF00158.26 EGC40024.1 - 0.079 12.7 0.0 0.23 11.2 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain ABC_tran PF00005.27 EGC40024.1 - 0.086 13.4 0.0 0.28 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter GCFC PF07842.12 EGC40024.1 - 0.14 11.8 0.0 0.22 11.1 0.0 1.2 1 0 0 1 1 1 0 GC-rich sequence DNA-binding factor-like protein T2SSE PF00437.20 EGC40024.1 - 0.18 10.9 0.0 0.52 9.3 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein Hat1_N PF10394.9 EGC40025.1 - 3.6e-45 154.1 1.7 3.6e-45 154.1 1.7 1.8 2 0 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_1 PF00583.25 EGC40025.1 - 0.00017 21.8 0.0 0.00042 20.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family MOZ_SAS PF01853.18 EGC40025.1 - 0.0024 17.6 0.2 0.0045 16.7 0.2 1.5 1 0 0 1 1 1 1 MOZ/SAS family GNAT_acetyltr_2 PF13718.6 EGC40025.1 - 0.018 14.5 3.7 2.2 7.6 0.0 2.2 2 0 0 2 2 2 0 GNAT acetyltransferase 2 Acetyltransf_7 PF13508.7 EGC40025.1 - 0.074 13.5 0.1 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain baeRF_family10 PF18854.1 EGC40025.1 - 0.56 10.4 2.6 1.4 9.1 2.5 1.7 2 0 0 2 2 2 0 Bacterial archaeo-eukaryotic release factor family 10 DUF4834 PF16118.5 EGC40025.1 - 0.95 10.5 7.9 2.7 9.0 7.9 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4834) DUF2722 PF10846.8 EGC40025.1 - 1.2 8.0 15.2 4.6 6.1 16.1 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Spt20 PF12090.8 EGC40025.1 - 2.5 7.7 20.3 1.9 8.1 18.7 1.6 2 0 0 2 2 2 0 Spt20 family ALMT PF11744.8 EGC40025.1 - 2.8 6.7 5.3 4 6.1 5.3 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter AIM3 PF17096.5 EGC40025.1 - 3.4 8.7 9.9 7.4 7.6 9.9 1.5 1 0 0 1 1 1 0 Altered inheritance of mitochondria protein 3 WW_1 PF18507.1 EGC40025.1 - 7.5 6.3 6.2 10 5.9 1.8 3.1 3 0 0 3 3 3 0 WW domain FNIP PF05725.12 EGC40026.1 - 3.3e-133 433.7 51.4 3.9e-16 58.9 0.1 11.2 7 3 2 11 11 11 11 FNIP Repeat Phage_min_tail PF05939.13 EGC40026.1 - 1.5e-07 31.8 0.0 51 4.3 0.0 9.3 4 3 5 11 11 11 1 Phage minor tail protein Bclx_interact PF08945.10 EGC40026.1 - 2 8.3 3.6 57 3.6 0.0 4.9 7 0 0 7 7 7 0 Bcl-x interacting, BH3 domain AsmA_2 PF13502.6 EGC40027.1 - 0.021 14.4 0.4 0.021 14.4 0.4 2.2 1 1 1 2 2 2 0 AsmA-like C-terminal region Amnionless PF14828.6 EGC40027.1 - 0.039 12.8 0.1 0.087 11.6 0.1 1.6 1 0 0 1 1 1 0 Amnionless TRAM_2 PF18693.1 EGC40027.1 - 0.059 13.5 0.6 1.8 8.8 0.1 2.7 2 0 0 2 2 2 0 TRAM domain TIM PF00121.18 EGC40028.1 - 3.5e-91 304.9 0.7 3.9e-91 304.7 0.7 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ubiquitin PF00240.23 EGC40029.1 - 3.9e-166 539.1 27.6 1.1e-32 111.5 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.8 EGC40029.1 - 4.4e-77 253.9 26.9 8.3e-15 54.4 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.6 EGC40029.1 - 4.7e-27 94.3 14.3 0.00093 19.6 0.1 7.0 5 5 0 5 5 5 5 Ubiquitin-like domain TBK1_ULD PF18396.1 EGC40029.1 - 8.6e-18 64.1 7.1 0.085 12.8 0.0 5.3 5 0 0 5 5 5 5 TANK binding kinase 1 ubiquitin-like domain Ubiquitin_5 PF18037.1 EGC40029.1 - 1.4e-17 63.8 11.5 0.061 13.7 0.1 5.1 5 0 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.6 EGC40029.1 - 2e-16 60.1 3.9 0.29 11.2 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.9 EGC40029.1 - 1.8e-15 57.4 1.6 0.66 10.6 0.0 5.2 1 1 2 5 5 5 5 DUF2407 ubiquitin-like domain Methyltrans_RNA PF04452.14 EGC40029.1 - 3.5e-08 33.0 2.1 2.3 7.5 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase DUF2870 PF11069.8 EGC40029.1 - 1.6e-07 31.6 0.0 40 4.7 0.0 5.9 5 0 0 5 5 5 0 Protein of unknown function (DUF2870) Ubiquitin_4 PF18036.1 EGC40029.1 - 5.1e-07 29.7 29.5 34 4.6 0.0 9.9 10 0 0 10 10 10 0 Ubiquitin-like domain Big_3_3 PF13750.6 EGC40029.1 - 7e-07 29.0 0.1 27 4.4 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) DUF969 PF06149.12 EGC40029.1 - 1.4e-05 24.6 0.1 28 4.1 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF969) DUF3861 PF12977.7 EGC40029.1 - 1.5e-05 25.1 3.3 48 4.2 0.0 5.2 5 0 0 5 5 5 0 Domain of Unknown Function with PDB structure (DUF3861) UDP-g_GGTase PF06427.11 EGC40029.1 - 1.7e-05 24.9 7.8 9.6 6.4 0.1 4.9 5 0 0 5 5 5 0 UDP-glucose:Glycoprotein Glucosyltransferase DUF3435 PF11917.8 EGC40029.1 - 5.5e-05 22.3 1.1 30 3.4 0.0 4.9 5 0 0 5 5 5 0 Protein of unknown function (DUF3435) Big_7 PF17957.1 EGC40029.1 - 6.6e-05 23.6 0.2 1.5e+02 3.3 0.0 5.0 5 0 0 5 5 5 0 Bacterial Ig domain Corona_NS2A PF05213.12 EGC40029.1 - 0.0002 20.8 0.1 58 2.9 0.0 4.8 5 0 0 5 5 5 0 Coronavirus NS2A protein ACT_5 PF13710.6 EGC40029.1 - 0.00046 20.0 5.7 56 3.7 0.0 5.2 5 0 0 5 5 5 0 ACT domain ORF11CD3 PF10549.9 EGC40029.1 - 0.00056 20.0 1.8 1.2e+02 2.9 0.0 6.3 10 0 0 10 10 5 0 ORF11CD3 domain YcgR_2 PF12945.7 EGC40029.1 - 0.00074 19.6 10.3 40 4.4 0.1 5.2 5 0 0 5 5 5 0 Flagellar protein YcgR ACT_4 PF13291.6 EGC40029.1 - 0.0017 18.9 0.7 2.4e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 ACT domain Imm12 PF15560.6 EGC40029.1 - 0.0026 17.7 3.6 1e+02 2.9 0.0 4.9 5 0 0 5 5 5 0 Immunity protein 12 NEAT PF05031.12 EGC40029.1 - 0.036 14.7 8.8 22 5.7 0.6 4.5 1 1 3 4 4 4 0 Iron Transport-associated domain Glyco_tran_WecB PF03808.13 EGC40029.1 - 0.074 13.0 0.0 2.7e+02 1.4 0.0 4.3 5 0 0 5 5 5 0 Glycosyl transferase WecB/TagA/CpsF family ProRS-C_2 PF09181.10 EGC40029.1 - 2.8 8.1 9.1 2.6e+02 1.8 0.1 4.8 5 0 0 5 5 5 0 Prolyl-tRNA synthetase, C-terminal PH_15 PF17339.2 EGC40029.1 - 7.8 6.5 10.9 1.2e+02 2.7 0.1 4.4 5 0 0 5 5 5 0 PH domain NICE-3 PF07406.11 EGC40030.1 - 1.2e-07 31.9 0.1 1.8e-07 31.3 0.1 1.3 1 0 0 1 1 1 1 NICE-3 protein Pox_EPC_I2-L1 PF12575.8 EGC40030.1 - 0.16 12.2 2.3 0.25 11.6 0.4 2.1 2 0 0 2 2 2 0 Poxvirus entry protein complex L1 and I2 PilX_N PF14341.6 EGC40030.1 - 5.1 7.1 5.5 0.76 9.8 0.4 2.0 2 0 0 2 2 2 0 PilX N-terminal BolA PF01722.18 EGC40031.1 - 2.7e-13 50.0 0.0 2.8e-13 49.9 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Thiolase_N PF00108.23 EGC40032.1 - 7.4e-84 281.2 1.3 9.5e-84 280.8 1.3 1.1 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.18 EGC40032.1 - 6.7e-46 154.9 2.3 1.2e-45 154.1 0.5 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.26 EGC40032.1 - 0.0017 18.0 2.0 0.004 16.8 0.1 2.3 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.10 EGC40032.1 - 0.099 12.5 0.8 10 6.0 0.1 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Cwf_Cwc_15 PF04889.12 EGC40033.1 - 0.0072 16.1 3.3 0.011 15.5 3.3 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein ATG16 PF08614.11 EGC40033.1 - 0.026 14.8 13.2 0.04 14.1 13.2 1.2 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) FAM76 PF16046.5 EGC40033.1 - 0.029 13.7 12.9 0.037 13.4 12.9 1.1 1 0 0 1 1 1 0 FAM76 protein DUF724 PF05266.14 EGC40033.1 - 0.1 12.4 7.4 0.038 13.8 5.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF724) ANAPC_CDC26 PF10471.9 EGC40033.1 - 3.1 8.7 11.5 1.7 9.5 4.6 2.5 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit CDC26 MALT1_Ig PF18703.1 EGC40033.1 - 6.4 6.8 10.1 0.76 9.8 1.3 2.8 1 1 1 3 3 3 0 MALT1 Ig-like domain Patatin PF01734.22 EGC40034.1 - 8e-24 84.9 0.0 2.6e-23 83.3 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase MMR_HSR1 PF01926.23 EGC40034.1 - 0.045 13.8 0.0 0.14 12.3 0.0 1.9 1 0 0 1 1 1 0 50S ribosome-binding GTPase ABC_tran PF00005.27 EGC40034.1 - 0.12 12.8 1.0 1.6 9.2 0.0 2.6 2 0 0 2 2 2 0 ABC transporter Phospholip_B PF04916.13 EGC40035.1 - 2.6e-168 560.9 15.1 3.1e-168 560.7 15.1 1.0 1 0 0 1 1 1 1 Phospholipase B COQ9 PF08511.11 EGC40036.1 - 1.6e-27 95.0 0.4 2.3e-27 94.6 0.4 1.2 1 0 0 1 1 1 1 COQ9 Pro_isomerase PF00160.21 EGC40037.1 - 2.2e-17 63.8 0.2 2.8e-17 63.4 0.2 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Lectin_legB PF00139.19 EGC40038.1 - 5.5e-14 52.3 0.0 7.7e-14 51.8 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain Bact_lectin PF18483.1 EGC40038.1 - 5.6e-09 36.3 0.1 6.7e-09 36.0 0.1 1.1 1 0 0 1 1 1 1 Bacterial lectin Scramblase PF03803.15 EGC40039.1 - 0.0083 15.4 0.1 0.023 14.0 0.1 1.8 1 1 0 1 1 1 1 Scramblase DUF4968 PF16338.5 EGC40039.1 - 0.082 13.2 6.9 3 8.2 0.0 4.8 4 2 1 5 5 5 0 Domain of unknown function (DUF4968) MFS_1 PF07690.16 EGC40040.1 - 7.9e-30 104.0 12.2 7.9e-30 104.0 12.2 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily PAS_3 PF08447.12 EGC40042.1 - 6.2e-09 36.0 0.0 1e-08 35.3 0.0 1.4 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.7 EGC40042.1 - 0.0004 20.6 0.0 0.001 19.3 0.0 1.7 1 0 0 1 1 1 1 PAS domain Zn_clus PF00172.18 EGC40042.1 - 0.0033 17.5 5.0 0.006 16.7 5.0 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.25 EGC40042.1 - 0.049 13.6 0.0 0.096 12.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold ASD2 PF08687.11 EGC40042.1 - 2.1 7.8 12.4 0.041 13.4 3.9 2.0 2 0 0 2 2 2 0 Apx/Shroom domain ASD2 FANCL_C PF11793.8 EGC40043.1 - 3.2e-06 27.2 6.7 1.3e-05 25.3 6.7 2.1 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.6 EGC40043.1 - 3.4e-06 27.3 10.2 3.4e-06 27.3 10.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.7 EGC40043.1 - 0.0003 21.0 8.1 0.00096 19.4 8.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-ANAPC11 PF12861.7 EGC40043.1 - 0.0012 18.9 5.6 0.0031 17.5 5.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_2 PF13923.6 EGC40043.1 - 0.0012 18.6 10.4 0.0027 17.5 10.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Arm_3 PF16186.5 EGC40043.1 - 0.02 14.5 1.7 0.042 13.4 0.1 2.4 2 0 0 2 2 2 0 Atypical Arm repeat Zf_RING PF16744.5 EGC40043.1 - 0.13 12.4 4.0 0.35 11.0 4.0 1.7 1 0 0 1 1 1 0 KIAA1045 RING finger RINGv PF12906.7 EGC40043.1 - 0.15 12.2 7.8 0.4 10.9 7.8 1.8 1 0 0 1 1 1 0 RING-variant domain Zn_ribbon_17 PF17120.5 EGC40043.1 - 0.31 10.7 6.4 0.73 9.5 6.4 1.6 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGC40043.1 - 0.34 10.8 17.4 0.13 12.2 11.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.29 EGC40043.1 - 3.5 7.6 7.2 9 6.3 7.2 1.8 1 0 0 1 1 1 0 PHD-finger C1_1 PF00130.22 EGC40043.1 - 7.5 6.5 13.9 0.44 10.5 7.9 2.1 2 1 1 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) GATase_7 PF13537.6 EGC40044.1 - 1.9e-13 50.4 0.0 3.4e-13 49.6 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.6 EGC40044.1 - 4.4e-13 49.6 0.0 7.9e-13 48.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.27 EGC40044.1 - 1.8e-09 37.3 0.0 3.2e-09 36.5 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_4 PF13230.6 EGC40044.1 - 0.022 13.7 0.0 0.035 13.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II UPRTase PF14681.6 EGC40044.1 - 0.032 13.7 0.0 0.073 12.5 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase GATase_2 PF00310.21 EGC40044.1 - 0.11 11.2 0.0 0.16 10.6 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferases class-II PRTase_2 PF15609.6 EGC40044.1 - 0.2 11.2 0.9 0.37 10.2 0.0 1.9 3 0 0 3 3 3 0 Phosphoribosyl transferase DBC1 PF14443.6 EGC40045.1 - 3.3e-38 130.5 0.0 3.3e-38 130.5 0.0 2.5 2 1 0 2 2 2 1 DBC1 Coilin_N PF15862.5 EGC40046.1 - 8.8e-07 28.8 15.0 8.8e-07 28.8 15.0 3.5 3 0 0 3 3 3 1 Coilin N-terminus Trypan_PARP PF05887.11 EGC40046.1 - 0.002 18.1 9.1 0.002 18.1 9.1 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) CBS PF00571.28 EGC40047.1 - 8.7e-20 70.9 3.5 7.2e-08 32.8 0.2 4.3 4 0 0 4 4 4 4 CBS domain Actin PF00022.19 EGC40048.1 - 2.7e-143 477.5 0.0 9.7e-143 475.6 0.0 1.7 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGC40049.1 - 6.6e-135 449.8 0.0 1.7e-133 445.2 0.0 2.0 1 1 0 1 1 1 1 Actin Actin PF00022.19 EGC40050.1 - 1.5e-50 172.0 0.0 5e-40 137.3 0.0 2.0 1 1 1 2 2 2 2 Actin HypD PF01924.16 EGC40050.1 - 0.066 12.3 0.0 0.086 11.9 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family NdhL PF10716.9 EGC40052.1 - 0.12 12.4 3.7 1.3 9.1 0.1 2.4 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit DUF4064 PF13273.6 EGC40052.1 - 1.5 9.2 15.3 4.6 7.6 2.6 3.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Wzy_C PF04932.15 EGC40052.1 - 6.5 6.4 14.7 4.2e+02 0.5 13.9 2.8 1 1 0 1 1 1 0 O-Antigen ligase Nucleoporin_FG PF13634.6 EGC40053.1 - 0.002 18.9 15.7 0.002 18.9 15.7 14.1 7 4 8 15 15 15 8 Nucleoporin FG repeat region DUF3824 PF12868.7 EGC40053.1 - 2.9 8.6 11.2 0.63 10.7 4.3 3.5 2 0 0 2 2 2 0 Domain of unknwon function (DUF3824) Actin PF00022.19 EGC40054.1 - 2.5e-64 217.4 0.0 3.8e-62 210.2 0.0 2.0 1 1 0 1 1 1 1 Actin DUF1772 PF08592.11 EGC40055.1 - 1.8e-17 64.0 0.4 1.8e-17 64.0 0.4 1.3 2 0 0 2 2 2 1 Domain of unknown function (DUF1772) DUF1772 PF08592.11 EGC40056.1 - 3.7e-26 92.1 0.0 4.6e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SAP PF02037.27 EGC40057.1 - 4.7e-06 26.2 0.3 8.8e-06 25.3 0.3 1.5 1 0 0 1 1 1 1 SAP domain F-box-like PF12937.7 EGC40057.1 - 0.00091 19.1 0.0 0.0027 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.33 EGC40057.1 - 0.036 14.0 0.3 0.15 12.0 0.1 2.2 2 0 0 2 2 2 0 F-box domain DNA_ligase_A_M PF01068.21 EGC40059.1 - 8.7e-64 214.9 0.0 1.3e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.14 EGC40059.1 - 1e-40 139.9 0.1 1.5e-40 139.3 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.15 EGC40059.1 - 3.4e-26 91.7 0.0 9.3e-26 90.3 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region RNA_ligase PF09414.10 EGC40059.1 - 0.00028 21.2 0.0 0.0018 18.6 0.1 2.1 1 1 1 2 2 2 1 RNA ligase DNA_ligase_OB_2 PF14743.6 EGC40059.1 - 0.0022 18.0 0.1 0.83 9.7 0.0 2.6 2 0 0 2 2 2 2 DNA ligase OB-like domain Pex19 PF04614.12 EGC40060.1 - 2.2e-09 37.5 27.6 4.7e-09 36.4 17.5 3.3 1 1 1 2 2 2 1 Pex19 protein family Mito_fiss_reg PF05308.11 EGC40060.1 - 0.12 12.4 2.2 0.21 11.6 2.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Aminopep PF10023.9 EGC40060.1 - 0.47 9.8 4.4 0.45 9.8 0.1 2.0 2 0 0 2 2 2 0 Putative aminopeptidase Tir_receptor_C PF07489.11 EGC40060.1 - 2.5 8.0 9.2 4.2 7.3 9.2 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.11 EGC40060.1 - 3.5 5.7 11.2 5.1 5.2 11.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC40060.1 - 3.5 7.6 16.5 5.1 7.1 16.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein GRIM-19 PF06212.12 EGC40061.1 - 5.3e-17 62.0 0.0 1.4e-16 60.7 0.0 1.6 1 1 1 2 2 2 1 GRIM-19 protein PsiA PF06952.11 EGC40061.1 - 0.0052 16.1 0.0 0.0066 15.7 0.0 1.1 1 0 0 1 1 1 1 PsiA protein Mitoc_mL59 PF18126.1 EGC40061.1 - 0.098 13.0 2.1 0.51 10.6 2.5 1.7 1 1 1 2 2 2 0 Mitochondrial ribosomal protein mL59 NLPC_P60 PF00877.19 EGC40062.1 - 5.5e-13 48.9 0.6 8.4e-13 48.3 0.6 1.3 1 1 0 1 1 1 1 NlpC/P60 family DUF1175 PF06672.11 EGC40062.1 - 0.067 12.9 0.0 7.1 6.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1175) RNA_lig_T4_1 PF09511.10 EGC40063.1 - 1.1e-24 87.5 0.0 2.6e-24 86.3 0.0 1.5 1 1 0 1 1 1 1 RNA ligase LOH1CR12 PF10158.9 EGC40064.1 - 0.00016 21.7 4.8 0.00032 20.7 4.8 1.5 1 0 0 1 1 1 1 Tumour suppressor protein YkyA PF10368.9 EGC40064.1 - 0.00045 19.9 8.8 0.0014 18.4 8.8 1.8 1 0 0 1 1 1 1 Putative cell-wall binding lipoprotein CSN4_RPN5_eIF3a PF18420.1 EGC40064.1 - 0.012 15.7 1.8 1.2 9.4 0.1 2.7 2 0 0 2 2 2 0 CSN4/RPN5/eIF3a helix turn helix domain KcnmB2_inactiv PF09303.10 EGC40064.1 - 0.013 15.3 1.4 0.041 13.7 0.0 2.3 2 0 0 2 2 2 0 KCNMB2, ball and chain domain FAS_I_H PF18314.1 EGC40064.1 - 0.053 13.1 1.0 0.095 12.3 1.0 1.4 1 0 0 1 1 1 0 Fatty acid synthase type I helical domain eIF3_N PF09440.10 EGC40064.1 - 1.2 9.6 9.5 0.66 10.4 0.2 2.7 1 1 1 2 2 2 0 eIF3 subunit 6 N terminal domain p450 PF00067.22 EGC40065.1 - 1.5e-32 113.0 0.0 1.7e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2207 PF09972.9 EGC40066.1 - 0.0086 14.9 0.7 0.0086 14.9 0.7 2.0 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) HXXEE PF13787.6 EGC40066.1 - 0.0096 16.7 0.5 0.014 16.2 0.5 1.2 1 0 0 1 1 1 1 Protein of unknown function with HXXEE motif UPF0242 PF06785.11 EGC40066.1 - 0.016 15.3 1.4 0.025 14.7 1.4 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) N-terminus DUP PF00674.18 EGC40066.1 - 0.051 13.7 3.1 0.082 13.1 0.1 2.4 1 1 1 2 2 2 0 DUP family SLC3A2_N PF16028.5 EGC40066.1 - 0.16 11.5 0.9 0.41 10.2 0.9 1.7 1 0 0 1 1 1 0 Solute carrier family 3 member 2 N-terminus DUF4191 PF13829.6 EGC40066.1 - 0.93 8.8 2.4 1.4 8.2 2.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phlebovirus_G1 PF07243.11 EGC40066.1 - 1.1 7.5 3.4 1.5 7.1 3.4 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 PigN PF04987.14 EGC40067.1 - 0.004 16.1 1.6 0.0054 15.7 1.6 1.1 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Glucos_trans_II PF14264.6 EGC40067.1 - 0.01 15.2 3.6 0.013 14.9 3.6 1.1 1 0 0 1 1 1 0 Glucosyl transferase GtrII PhoLip_ATPase_C PF16212.5 EGC40067.1 - 0.02 14.7 3.4 0.028 14.2 3.4 1.1 1 0 0 1 1 1 0 Phospholipid-translocating P-type ATPase C-terminal Wzy_C PF04932.15 EGC40067.1 - 0.15 11.7 1.2 0.22 11.1 1.3 1.4 1 1 0 1 1 1 0 O-Antigen ligase DUF3290 PF11694.8 EGC40067.1 - 3.7 7.5 11.4 0.073 13.0 4.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3290) C2 PF00168.30 EGC40068.1 - 4.8e-22 78.2 0.0 7.3e-22 77.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain AAA_16 PF13191.6 EGC40069.1 - 5.4e-13 49.7 0.0 1.6e-12 48.1 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.6 EGC40069.1 - 0.012 15.9 0.0 0.32 11.3 0.0 3.0 1 1 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC40069.1 - 0.064 13.2 0.3 2.1 8.3 0.0 2.8 2 0 0 2 2 2 0 NACHT domain Ccdc124 PF06244.12 EGC40070.1 - 1.2e-37 129.4 5.3 1.2e-37 129.4 5.3 3.0 1 1 1 2 2 2 1 Coiled-coil domain-containing protein 124 /Oxs1 Red1 PF07964.11 EGC40070.1 - 4.9 5.3 28.2 6.1 4.9 28.2 1.1 1 0 0 1 1 1 0 Rec10 / Red1 cobW PF02492.19 EGC40071.1 - 7.3e-42 142.9 2.4 2.2e-41 141.4 2.4 1.7 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.14 EGC40071.1 - 2.6e-23 81.7 0.0 5.6e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain RsgA_GTPase PF03193.16 EGC40071.1 - 6.7e-05 22.9 1.0 0.28 11.1 0.1 2.3 2 0 0 2 2 2 2 RsgA GTPase MobB PF03205.14 EGC40071.1 - 0.0056 16.6 0.0 0.011 15.6 0.0 1.6 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SSE PF00437.20 EGC40071.1 - 0.0095 15.0 0.0 0.015 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Zeta_toxin PF06414.12 EGC40071.1 - 0.014 14.7 0.0 1.2 8.4 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin GTP_EFTU PF00009.27 EGC40071.1 - 0.014 15.0 0.1 0.6 9.6 0.0 2.3 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain SRP54 PF00448.22 EGC40071.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain MMR_HSR1_Xtn PF16897.5 EGC40071.1 - 0.037 14.0 0.2 0.14 12.2 0.2 1.9 1 0 0 1 1 1 0 C-terminal region of MMR_HSR1 domain NB-ARC PF00931.22 EGC40071.1 - 0.045 12.9 0.5 0.082 12.1 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.18 EGC40071.1 - 0.067 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase TsaE PF02367.17 EGC40071.1 - 0.073 13.1 0.0 0.16 11.9 0.0 1.5 1 0 0 1 1 1 0 Threonylcarbamoyl adenosine biosynthesis protein TsaE AAA_22 PF13401.6 EGC40071.1 - 0.16 12.2 0.0 0.32 11.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain dNK PF01712.19 EGC40071.1 - 0.61 9.9 3.1 2.5 7.9 0.1 2.3 1 1 1 2 2 2 0 Deoxynucleoside kinase NodZ PF05830.11 EGC40072.1 - 0.033 13.0 0.0 0.052 12.3 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) SLT PF01464.20 EGC40073.1 - 5.2e-12 45.4 0.0 7.5e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.20 EGC40073.1 - 0.00019 21.7 1.4 0.0064 16.7 1.4 2.1 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Cofilin_ADF PF00241.20 EGC40074.1 - 1.5e-36 124.9 2.9 6.3e-19 68.0 0.1 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Ribosomal_L2_C PF03947.18 EGC40075.1 - 6.9e-45 152.3 3.7 1.3e-44 151.5 3.7 1.4 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.23 EGC40075.1 - 2.8e-21 75.3 0.0 9e-21 73.6 0.0 1.9 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PRP3 PF08572.10 EGC40077.1 - 1.7e-54 185.0 14.7 1.7e-54 185.0 14.7 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.12 EGC40077.1 - 1e-36 126.2 0.0 1e-36 126.2 0.0 3.6 3 1 1 4 4 4 1 Protein of unknown function (DUF1115) Myosin_head PF00063.21 EGC40078.1 - 1.1e-259 863.3 10.4 1.1e-259 863.3 10.4 2.3 3 0 0 3 3 2 1 Myosin head (motor domain) MyTH4 PF00784.17 EGC40078.1 - 8.9e-50 167.7 9.1 4.5e-28 97.9 0.1 3.2 3 0 0 3 3 2 2 MyTH4 domain SH3_2 PF07653.17 EGC40078.1 - 8.5e-10 38.2 0.0 1.8e-09 37.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain RA PF00788.23 EGC40078.1 - 2.9e-09 37.4 0.1 1.1e-05 26.0 0.1 4.3 4 0 0 4 4 3 1 Ras association (RalGDS/AF-6) domain SH3_9 PF14604.6 EGC40078.1 - 9.3e-07 28.6 0.0 1.9e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.28 EGC40078.1 - 1.9e-06 27.4 0.0 5.2e-06 26.0 0.0 1.8 1 0 0 1 1 1 1 SH3 domain FERM_C PF09380.10 EGC40078.1 - 0.00039 20.7 9.0 0.00054 20.3 0.2 3.5 3 0 0 3 3 3 1 FERM C-terminal PH-like domain IQ PF00612.27 EGC40078.1 - 0.00095 18.8 14.3 0.02 14.6 1.7 4.1 4 0 0 4 4 4 2 IQ calmodulin-binding motif AAA_16 PF13191.6 EGC40078.1 - 0.0029 18.0 0.5 0.084 13.3 0.0 3.1 3 0 0 3 3 3 1 AAA ATPase domain FERM_N PF09379.10 EGC40078.1 - 0.015 15.2 0.1 0.11 12.5 0.1 2.4 2 0 0 2 2 2 0 FERM N-terminal domain AAA_22 PF13401.6 EGC40078.1 - 0.023 15.0 0.2 0.35 11.1 0.0 3.1 4 0 0 4 4 3 0 AAA domain Fascin PF06268.13 EGC40079.1 - 1.4e-15 57.4 4.7 5.3e-10 39.5 0.6 2.1 1 1 1 2 2 2 2 Fascin domain FRG1 PF06229.12 EGC40079.1 - 6.2e-06 26.0 0.2 0.014 15.1 0.0 2.7 1 1 1 2 2 2 2 FRG1-like domain FGF PF00167.18 EGC40079.1 - 0.00099 19.2 0.3 0.0027 17.8 0.1 1.7 1 1 1 2 2 2 2 Fibroblast growth factor DUF569 PF04601.13 EGC40079.1 - 0.051 13.3 0.1 0.18 11.5 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF569) DUF31 PF01732.16 EGC40080.1 - 0.18 11.3 14.7 9.3 5.7 0.1 3.6 1 1 1 3 3 3 0 Putative peptidase (DUF31) Pro_CA PF00484.19 EGC40081.1 - 7.4e-50 169.3 0.0 1.1e-49 168.7 0.0 1.3 1 0 0 1 1 1 1 Carbonic anhydrase EF-hand_7 PF13499.6 EGC40082.1 - 1.9e-12 47.4 14.4 3.4e-06 27.4 4.1 3.0 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.6 EGC40082.1 - 1.4e-11 43.4 12.7 0.00056 19.6 0.8 4.9 4 1 2 6 6 6 4 EF-hand domain EF-hand_1 PF00036.32 EGC40082.1 - 2.7e-08 32.8 10.1 0.007 15.8 0.2 4.8 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.6 EGC40082.1 - 2.8e-05 23.8 3.5 0.36 10.7 0.6 3.5 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.9 EGC40082.1 - 0.00024 21.4 1.4 0.13 12.6 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.7 EGC40082.1 - 0.0022 17.9 1.6 0.0022 17.9 1.6 1.7 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pam16 PF03656.13 EGC40082.1 - 0.29 11.1 3.1 0.93 9.5 0.9 2.1 2 0 0 2 2 2 0 Pam16 IP_trans PF02121.18 EGC40083.1 - 3.6e-112 373.9 0.4 4.1e-112 373.7 0.4 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Bromodomain PF00439.25 EGC40084.1 - 3e-22 78.5 2.4 3e-22 78.5 2.4 2.4 2 0 0 2 2 2 1 Bromodomain CDC45 PF02724.14 EGC40084.1 - 4.7 5.4 45.9 0.099 10.9 30.5 2.2 2 0 0 2 2 2 0 CDC45-like protein DUF4551 PF15087.6 EGC40084.1 - 9.6 4.9 43.1 0.48 9.2 20.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4551) COX_ARM PF06481.14 EGC40085.1 - 0.1 12.5 2.9 4.5 7.3 0.1 3.0 1 1 2 3 3 3 0 COX Aromatic Rich Motif Aquarius_N PF16399.5 EGC40086.1 - 2e-190 634.7 29.8 3.2e-190 634.1 29.8 1.2 1 0 0 1 1 1 1 Intron-binding protein aquarius N-terminus AAA_12 PF13087.6 EGC40086.1 - 1.1e-29 103.5 0.1 8e-29 100.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.6 EGC40086.1 - 3.4e-27 95.9 0.1 3.4e-27 95.9 0.1 3.1 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.6 EGC40086.1 - 8.9e-09 35.8 0.0 3.4e-07 30.7 0.0 2.6 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.6 EGC40086.1 - 1.7e-08 34.4 0.0 0.00038 20.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain ResIII PF04851.15 EGC40086.1 - 4.9e-06 26.6 0.2 4.9e-06 26.6 0.2 3.0 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit Viral_helicase1 PF01443.18 EGC40086.1 - 4.7e-05 23.2 0.0 1 9.0 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase Parvo_NS1 PF01057.17 EGC40086.1 - 0.00089 18.4 0.2 0.004 16.3 0.1 2.2 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 ATPase PF06745.13 EGC40086.1 - 0.00098 18.5 0.0 0.0043 16.4 0.0 2.1 1 0 0 1 1 1 1 KaiC DEAD PF00270.29 EGC40086.1 - 0.0036 17.1 0.1 0.012 15.4 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase DUF2075 PF09848.9 EGC40086.1 - 0.004 16.4 5.2 0.0071 15.6 0.0 3.1 3 0 0 3 3 3 1 Uncharacterized conserved protein (DUF2075) AAA_16 PF13191.6 EGC40086.1 - 0.0041 17.5 0.0 1.9 8.8 0.0 2.6 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.13 EGC40086.1 - 0.0049 16.1 0.1 0.067 12.4 0.0 2.4 2 0 0 2 2 2 1 TIP49 P-loop domain AAA_25 PF13481.6 EGC40086.1 - 0.0062 16.1 0.0 0.013 15.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA PF00004.29 EGC40086.1 - 0.0078 16.6 0.0 0.028 14.9 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) PhoH PF02562.16 EGC40086.1 - 0.0079 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein UvrD_C_2 PF13538.6 EGC40086.1 - 0.011 15.6 0.0 0.021 14.6 0.0 1.5 1 0 0 1 1 1 0 UvrD-like helicase C-terminal domain DnaB_C PF03796.15 EGC40086.1 - 0.024 14.0 0.2 0.063 12.6 0.0 1.7 2 0 0 2 2 2 0 DnaB-like helicase C terminal domain RecA PF00154.21 EGC40086.1 - 0.068 12.6 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 recA bacterial DNA recombination protein KHA PF11834.8 EGC40086.1 - 0.07 13.2 0.0 0.25 11.5 0.0 2.0 1 0 0 1 1 1 0 KHA, dimerisation domain of potassium ion channel AAA_5 PF07728.14 EGC40086.1 - 0.077 13.0 0.0 0.35 10.9 0.0 2.1 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Acetyltransf_18 PF18014.1 EGC40086.1 - 0.12 12.2 0.0 10 6.0 0.0 2.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain DUF2183 PF09949.9 EGC40086.1 - 2.1 8.8 7.7 16 5.9 0.0 4.9 5 1 0 5 5 5 0 Uncharacterized conserved protein (DUF2183) ATP-synt_D PF01813.17 EGC40087.1 - 2.7e-67 226.4 3.7 3.9e-67 225.9 3.7 1.2 1 0 0 1 1 1 1 ATP synthase subunit D LIN52 PF10044.9 EGC40088.1 - 1.8e-07 31.8 0.1 3.2e-07 30.9 0.1 1.4 1 0 0 1 1 1 1 Retinal tissue protein Gluconate_2-dh3 PF13618.6 EGC40088.1 - 0.083 13.1 0.0 0.083 13.1 0.0 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 FtsK_SpoIIIE_N PF12538.8 EGC40092.1 - 0.41 10.9 17.9 0.13 12.5 9.1 2.8 1 1 1 2 2 2 0 DNA transporter Cyclin_N PF00134.23 EGC40093.1 - 0.06 13.1 1.0 0.14 11.9 1.0 1.6 1 0 0 1 1 1 0 Cyclin, N-terminal domain CDC45 PF02724.14 EGC40094.1 - 0.94 7.7 7.8 1 7.6 7.8 1.2 1 0 0 1 1 1 0 CDC45-like protein Mob_Pre PF01076.19 EGC40096.1 - 0.014 15.3 3.0 0.014 15.3 3.0 2.1 2 0 0 2 2 2 0 Plasmid recombination enzyme Radical_SAM PF04055.21 EGC40098.1 - 5.7e-14 52.8 0.0 1.1e-13 51.9 0.0 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.6 EGC40098.1 - 1.2e-06 28.6 0.0 3.4e-06 27.2 0.0 1.7 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.6 EGC40098.1 - 9.1e-05 22.7 0.1 0.00021 21.6 0.1 1.5 1 0 0 1 1 1 1 4Fe-4S single cluster domain P2X_receptor PF00864.19 EGC40099.1 - 4.9e-26 91.7 1.2 4e-12 45.9 0.4 2.4 1 1 1 2 2 2 2 ATP P2X receptor DUF3206 PF11472.8 EGC40100.1 - 0.042 13.8 0.1 0.089 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Glutaredoxin PF00462.24 EGC40101.1 - 3.4e-17 62.4 0.0 4.9e-17 61.9 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Peptidase_S28 PF05577.12 EGC40102.1 - 1.7e-117 392.9 3.1 2e-117 392.7 3.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.20 EGC40102.1 - 8.2e-06 25.6 0.2 2.3e-05 24.2 0.0 1.8 2 1 0 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC40102.1 - 0.00069 19.2 0.0 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S37 PF05576.11 EGC40102.1 - 0.0059 15.3 0.3 0.009 14.7 0.3 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Gag_MA PF01140.19 EGC40102.1 - 0.085 12.6 0.1 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Matrix protein (MA), p15 Choline_transpo PF04515.12 EGC40103.1 - 7.6e-47 160.1 28.4 7.6e-47 160.1 28.4 1.9 1 1 1 2 2 2 1 Plasma-membrane choline transporter Sulfotransfer_2 PF03567.14 EGC40104.1 - 1.4e-07 31.7 1.3 1.4e-07 31.7 1.3 3.1 2 1 0 2 2 2 1 Sulfotransferase family Folate_carrier PF01770.18 EGC40104.1 - 0.043 12.6 2.8 0.074 11.8 2.8 1.5 1 0 0 1 1 1 0 Reduced folate carrier Zip PF02535.22 EGC40104.1 - 0.062 12.5 2.3 0.094 11.9 2.3 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC40104.1 - 0.095 11.4 8.5 0.16 10.7 8.5 1.4 1 0 0 1 1 1 0 Presenilin CLN3 PF02487.17 EGC40104.1 - 0.12 11.4 1.4 0.29 10.1 1.4 1.6 1 0 0 1 1 1 0 CLN3 protein ALMT PF11744.8 EGC40104.1 - 1.1 8.0 9.2 2.4 6.9 9.2 1.6 1 0 0 1 1 1 0 Aluminium activated malate transporter EOS1 PF12326.8 EGC40104.1 - 1.4 8.8 5.2 3.1 7.7 5.2 1.6 1 0 0 1 1 1 0 N-glycosylation protein DUF3439 PF11921.8 EGC40105.1 - 0.13 12.2 4.8 0.13 12.2 4.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Androgen_recep PF02166.16 EGC40105.1 - 0.67 8.7 7.4 0.63 8.8 7.4 1.0 1 0 0 1 1 1 0 Androgen receptor DUF2935 PF11155.8 EGC40107.1 - 0.0086 16.4 1.8 0.021 15.1 1.8 1.6 1 1 0 1 1 1 1 Domain of unknown function (DUF2935) ApoC-I PF04691.12 EGC40107.1 - 0.58 10.1 6.2 12 5.9 0.1 2.6 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) Oxidored_molyb PF00174.19 EGC40108.1 - 3e-58 196.2 0.0 5.1e-58 195.5 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.16 EGC40108.1 - 2.5e-32 111.8 0.0 5.3e-32 110.7 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain GTP_EFTU PF00009.27 EGC40109.1 - 1.6e-32 112.6 0.0 4.7e-32 111.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.8 EGC40109.1 - 4.3e-13 49.3 5.0 5.3e-13 49.0 1.1 3.0 4 0 0 4 4 4 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.25 EGC40109.1 - 3.3e-12 46.6 1.0 1.5e-08 34.9 0.0 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.6 EGC40109.1 - 3.9e-10 39.5 0.3 1.1e-09 38.1 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.23 EGC40109.1 - 8.4e-09 35.5 0.1 4.6e-08 33.1 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Roc PF08477.13 EGC40109.1 - 2.9e-05 24.3 0.0 0.00013 22.1 0.0 2.2 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase ATP_bind_1 PF03029.17 EGC40109.1 - 0.0017 18.2 0.0 0.0059 16.4 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_22 PF13401.6 EGC40109.1 - 0.002 18.4 0.0 0.0082 16.4 0.0 2.0 2 0 0 2 2 2 1 AAA domain SRPRB PF09439.10 EGC40109.1 - 0.0091 15.4 0.1 0.049 13.1 0.1 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.22 EGC40109.1 - 0.018 14.6 0.1 0.15 11.6 0.0 2.7 2 1 0 2 2 2 0 Ras family ATF7IP_BD PF16788.5 EGC40109.1 - 0.058 13.5 15.5 4.9 7.2 11.9 2.6 2 1 0 2 2 2 0 ATF-interacting protein binding domain FeoB_N PF02421.18 EGC40109.1 - 0.07 12.7 0.6 0.55 9.7 0.1 2.7 2 2 1 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.23 EGC40109.1 - 0.79 9.8 6.4 12 5.9 0.0 3.4 2 1 1 3 3 3 0 Dynamin family DNA_pol_phi PF04931.13 EGC40110.1 - 0.14 10.2 20.2 0.14 10.2 20.2 1.0 1 0 0 1 1 1 0 DNA polymerase phi SDA1 PF05285.12 EGC40110.1 - 0.34 10.3 16.2 0.32 10.4 16.2 1.0 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.10 EGC40110.1 - 0.46 9.8 13.2 0.41 9.9 13.2 1.0 1 0 0 1 1 1 0 BUD22 CobT PF06213.12 EGC40110.1 - 0.5 9.7 11.4 0.49 9.7 11.4 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Nop14 PF04147.12 EGC40110.1 - 0.94 7.6 16.4 0.83 7.8 16.4 1.0 1 0 0 1 1 1 0 Nop14-like family NOA36 PF06524.12 EGC40110.1 - 0.94 8.7 15.1 0.87 8.9 15.1 1.1 1 0 0 1 1 1 0 NOA36 protein Cwf_Cwc_15 PF04889.12 EGC40110.1 - 1.6 8.4 20.3 1.9 8.2 20.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Polyoma_lg_T_C PF06431.11 EGC40110.1 - 2 7.2 6.1 1.9 7.2 6.1 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CDC45 PF02724.14 EGC40110.1 - 3 6.0 12.5 2.8 6.1 12.5 1.0 1 0 0 1 1 1 0 CDC45-like protein Sigma70_ner PF04546.13 EGC40110.1 - 4.9 7.0 13.6 5.5 6.8 13.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region MBOAT PF03062.19 EGC40111.1 - 1.6e-50 172.4 9.6 3.3e-50 171.4 9.6 1.6 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family Ribosomal_L5e PF17144.4 EGC40112.1 - 8.4e-81 269.8 0.8 8.4e-81 269.8 0.8 1.5 2 0 0 2 2 2 1 Ribosomal large subunit proteins 60S L5, and 50S L18 Ribosomal_L18_c PF14204.6 EGC40112.1 - 4.3e-31 107.7 4.8 4.3e-31 107.7 4.8 2.0 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.6 EGC40112.1 - 0.047 13.9 0.1 0.4 10.9 0.1 2.3 1 1 0 1 1 1 0 Threonine synthase N terminus DIOX_N PF14226.6 EGC40113.1 - 3e-24 86.0 0.0 5.8e-24 85.1 0.0 1.4 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.20 EGC40113.1 - 2e-14 53.9 0.0 3.4e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily AAA PF00004.29 EGC40114.1 - 5.3e-31 107.8 0.1 1.3e-30 106.5 0.1 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.6 EGC40114.1 - 2.9e-07 30.4 0.2 1.7e-06 27.9 0.1 2.3 2 1 0 2 2 1 1 AAA domain AAA_22 PF13401.6 EGC40114.1 - 5.3e-07 30.0 0.6 1.7e-06 28.4 0.1 2.0 2 2 0 2 2 2 1 AAA domain AAA_18 PF13238.6 EGC40114.1 - 1.2e-06 29.1 0.0 2.6e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.14 EGC40114.1 - 9.3e-06 25.7 0.2 4.3e-05 23.5 0.1 2.2 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) ATPase_2 PF01637.18 EGC40114.1 - 1.5e-05 25.0 6.6 0.0005 20.1 0.0 3.1 2 1 1 3 3 3 2 ATPase domain predominantly from Archaea AAA_25 PF13481.6 EGC40114.1 - 5.6e-05 22.8 0.1 0.032 13.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.6 EGC40114.1 - 6e-05 23.1 1.6 9.9e-05 22.4 0.1 2.2 2 1 1 3 3 3 1 AAA domain AAA_16 PF13191.6 EGC40114.1 - 8.3e-05 23.0 0.0 0.00022 21.6 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RNA_helicase PF00910.22 EGC40114.1 - 0.00026 21.4 0.2 0.00094 19.6 0.0 2.1 2 0 0 2 2 1 1 RNA helicase AAA_2 PF07724.14 EGC40114.1 - 0.00026 21.2 0.1 0.0017 18.5 0.1 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.17 EGC40114.1 - 0.00036 20.3 0.0 0.0011 18.7 0.0 1.8 2 0 0 2 2 1 1 IstB-like ATP binding protein RuvB_N PF05496.12 EGC40114.1 - 0.00075 19.3 0.4 0.0053 16.5 0.0 2.4 2 1 1 3 3 3 1 Holliday junction DNA helicase RuvB P-loop domain PhoH PF02562.16 EGC40114.1 - 0.0012 18.4 0.1 0.004 16.6 0.0 1.9 2 0 0 2 2 2 1 PhoH-like protein AAA_28 PF13521.6 EGC40114.1 - 0.0016 18.7 0.0 0.0031 17.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.6 EGC40114.1 - 0.0016 18.6 0.0 0.0031 17.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.12 EGC40114.1 - 0.0018 18.2 0.4 0.0043 17.0 0.0 1.9 2 1 0 2 2 1 1 NACHT domain DUF815 PF05673.13 EGC40114.1 - 0.0026 16.9 0.0 0.034 13.3 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.6 EGC40114.1 - 0.003 17.7 0.0 0.0082 16.3 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain PIF1 PF05970.14 EGC40114.1 - 0.0033 16.6 0.3 0.014 14.6 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Mg_chelatase PF01078.21 EGC40114.1 - 0.0041 16.5 0.0 0.0078 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_30 PF13604.6 EGC40114.1 - 0.0045 16.7 0.0 0.015 15.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain KAP_NTPase PF07693.14 EGC40114.1 - 0.006 15.9 1.8 2.3 7.3 0.0 2.5 1 1 0 2 2 2 2 KAP family P-loop domain TsaE PF02367.17 EGC40114.1 - 0.0062 16.5 0.0 0.013 15.5 0.0 1.5 1 0 0 1 1 1 1 Threonylcarbamoyl adenosine biosynthesis protein TsaE Cytidylate_kin PF02224.18 EGC40114.1 - 0.0064 16.2 0.1 0.017 14.8 0.1 1.7 1 1 0 1 1 1 1 Cytidylate kinase AAA_7 PF12775.7 EGC40114.1 - 0.0071 15.9 0.0 0.017 14.7 0.0 1.6 1 0 0 1 1 1 1 P-loop containing dynein motor region TIP49 PF06068.13 EGC40114.1 - 0.0073 15.6 1.6 0.013 14.7 0.0 2.1 3 0 0 3 3 2 1 TIP49 P-loop domain AAA_19 PF13245.6 EGC40114.1 - 0.0077 16.6 0.2 0.079 13.3 0.0 2.5 1 1 1 2 2 2 1 AAA domain NB-ARC PF00931.22 EGC40114.1 - 0.0086 15.3 0.1 0.021 14.0 0.0 1.7 2 0 0 2 2 1 1 NB-ARC domain AAA_11 PF13086.6 EGC40114.1 - 0.01 15.6 0.2 0.031 14.0 0.2 1.9 1 1 0 1 1 1 0 AAA domain PduV-EutP PF10662.9 EGC40114.1 - 0.011 15.5 0.0 0.025 14.3 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation ABC_tran PF00005.27 EGC40114.1 - 0.012 16.1 0.3 0.03 14.9 0.1 1.9 2 1 0 2 2 1 0 ABC transporter Parvo_NS1 PF01057.17 EGC40114.1 - 0.015 14.4 0.0 0.035 13.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 Rad17 PF03215.15 EGC40114.1 - 0.02 14.8 1.2 0.083 12.8 0.2 2.5 2 1 0 2 2 2 0 Rad17 P-loop domain DUF2075 PF09848.9 EGC40114.1 - 0.021 14.1 0.0 0.047 12.9 0.0 1.5 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DnaB_C PF03796.15 EGC40114.1 - 0.028 13.8 0.2 0.093 12.0 0.0 1.9 2 1 0 2 2 2 0 DnaB-like helicase C terminal domain SKI PF01202.22 EGC40114.1 - 0.051 13.7 0.1 0.14 12.2 0.0 1.8 2 0 0 2 2 1 0 Shikimate kinase Sigma54_activat PF00158.26 EGC40114.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain MMR_HSR1 PF01926.23 EGC40114.1 - 0.062 13.4 0.0 0.16 12.1 0.0 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_17 PF13207.6 EGC40114.1 - 0.074 13.5 0.0 0.24 11.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain ATPase PF06745.13 EGC40114.1 - 0.077 12.3 2.6 2.9 7.2 0.0 3.0 2 1 1 3 3 3 0 KaiC Zeta_toxin PF06414.12 EGC40114.1 - 0.1 11.9 0.0 0.21 10.8 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin ResIII PF04851.15 EGC40114.1 - 0.17 11.9 1.2 0.4 10.7 1.0 2.0 1 1 0 1 1 1 0 Type III restriction enzyme, res subunit AAA_23 PF13476.6 EGC40114.1 - 1.3 9.5 14.0 0.06 13.8 0.8 2.4 1 1 1 2 2 2 0 AAA domain zf-MYND PF01753.18 EGC40115.1 - 5.7e-08 32.7 12.0 1.1e-07 31.8 12.0 1.5 1 0 0 1 1 1 1 MYND finger zf-FLZ PF04570.14 EGC40115.1 - 0.18 11.3 4.1 0.46 10.0 4.1 1.7 1 0 0 1 1 1 0 zinc-finger of the FCS-type, C2-C2 AOX PF01786.17 EGC40116.1 - 6.9e-63 212.1 0.4 9.3e-63 211.7 0.4 1.1 1 0 0 1 1 1 1 Alternative oxidase COQ7 PF03232.13 EGC40116.1 - 0.17 11.6 0.0 0.28 10.9 0.0 1.3 1 0 0 1 1 1 0 Ubiquinone biosynthesis protein COQ7 AOX PF01786.17 EGC40117.1 - 8.6e-71 237.9 0.3 1.1e-70 237.5 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase PTE PF02126.18 EGC40118.1 - 2.2e-83 280.2 0.4 2.8e-83 279.8 0.4 1.1 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.21 EGC40118.1 - 0.00019 20.9 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase DUF1788 PF08747.11 EGC40118.1 - 0.072 13.1 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1788) NBD94 PF16830.5 EGC40118.1 - 0.084 13.3 0.9 0.084 13.3 0.9 2.7 3 0 0 3 3 3 0 Nucleotide-Binding Domain 94 of RH Sec3_C_2 PF15278.6 EGC40118.1 - 0.11 12.8 0.0 7.4 7.0 0.0 3.2 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Sybindin PF04099.12 EGC40119.1 - 1.1e-48 164.8 0.3 1.2e-48 164.7 0.3 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.13 EGC40119.1 - 4.2e-07 30.1 0.0 4.5e-07 30.1 0.0 1.2 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3430 PF11912.8 EGC40120.1 - 1.4e-25 90.7 25.2 1.6e-25 90.4 25.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Sec62 PF03839.16 EGC40121.1 - 0.0051 16.4 4.3 0.0051 16.4 4.3 2.5 2 1 1 3 3 3 1 Translocation protein Sec62 CUE PF02845.16 EGC40122.1 - 1.4e-07 31.0 0.2 1.4e-07 31.0 0.2 2.0 2 0 0 2 2 2 1 CUE domain CENP-U PF13097.6 EGC40122.1 - 0.0025 17.8 10.1 0.0025 17.8 10.1 1.9 2 0 0 2 2 2 1 CENP-A nucleosome associated complex (NAC) subunit UBA_4 PF14555.6 EGC40122.1 - 0.018 14.8 0.1 0.067 13.0 0.1 2.0 1 0 0 1 1 1 0 UBA-like domain DMA PF03474.14 EGC40122.1 - 0.077 12.6 0.0 0.19 11.3 0.0 1.7 1 0 0 1 1 1 0 DMRTA motif SNARE PF05739.19 EGC40123.1 - 9.1e-08 32.0 1.0 2.1e-07 30.8 0.4 1.7 2 0 0 2 2 2 1 SNARE domain ETRAMP PF09716.10 EGC40123.1 - 0.045 13.8 0.7 0.043 13.9 0.7 1.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Synaptobrevin PF00957.21 EGC40123.1 - 0.21 11.4 4.3 0.12 12.1 1.2 1.9 2 0 0 2 2 2 0 Synaptobrevin Npa1 PF11707.8 EGC40124.1 - 8.2e-52 176.7 9.1 8.2e-52 176.7 9.1 5.7 6 1 0 6 6 6 1 Ribosome 60S biogenesis N-terminal NopRA1 PF16201.5 EGC40124.1 - 9.6e-21 74.3 4.0 9.6e-21 74.3 4.0 4.8 4 0 0 4 4 4 1 Nucleolar pre-ribosomal-associated protein 1 Esterase PF00756.20 EGC40125.1 - 9.3e-39 133.6 0.0 1.1e-38 133.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.21 EGC40125.1 - 0.00011 21.8 0.1 0.00013 21.5 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.16 EGC40125.1 - 0.0016 18.3 0.0 0.0021 17.9 0.0 1.3 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.8 EGC40125.1 - 0.0037 16.6 0.0 0.0061 15.8 0.0 1.3 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Chlorophyllase2 PF12740.7 EGC40125.1 - 0.0092 14.9 0.0 0.026 13.5 0.0 1.8 1 1 0 1 1 1 1 Chlorophyllase enzyme Abhydrolase_1 PF00561.20 EGC40125.1 - 0.025 14.2 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold PGAP1 PF07819.13 EGC40125.1 - 0.041 13.6 0.0 0.067 12.9 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein MIT PF04212.18 EGC40127.1 - 2e-12 47.0 1.6 4.3e-12 45.9 1.6 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain BRO1 PF03097.18 EGC40127.1 - 0.024 13.4 0.0 0.043 12.6 0.0 1.3 1 0 0 1 1 1 0 BRO1-like domain TPR_2 PF07719.17 EGC40127.1 - 0.039 14.1 1.2 0.24 11.6 0.3 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat Sec5 PF15469.6 EGC40127.1 - 0.051 13.4 0.2 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Exocyst complex component Sec5 DUF4398 PF14346.6 EGC40127.1 - 0.18 12.5 0.8 17 6.1 0.0 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4398) PI3Ka PF00613.20 EGC40128.1 - 2.5e-61 206.3 1.2 5.3e-61 205.3 1.2 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.27 EGC40128.1 - 9.7e-54 182.8 0.0 2.7e-52 178.1 0.0 2.7 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.24 EGC40128.1 - 4.3e-29 101.2 0.0 1.2e-28 99.8 0.0 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.18 EGC40128.1 - 4.2e-25 88.0 0.3 1e-22 80.3 0.0 3.7 2 1 1 3 3 3 2 PI3-kinase family, ras-binding domain DUF4135 PF13575.6 EGC40128.1 - 0.0093 15.3 0.0 0.019 14.3 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4135) Evr1_Alr PF04777.13 EGC40129.1 - 6.1e-09 36.3 0.0 2.6e-08 34.2 0.0 2.2 1 0 0 1 1 1 1 Erv1 / Alr family U62_UL91 PF17442.2 EGC40129.1 - 0.002 18.0 0.0 0.079 13.0 0.0 2.6 2 0 0 2 2 2 1 Functional domain of U62 and UL91 proteins DUF5423 PF17461.2 EGC40129.1 - 1.9 7.2 5.9 3.4 6.4 5.9 1.3 1 0 0 1 1 1 0 Family of unknown function (DUF5423) Pkinase PF00069.25 EGC40130.1 - 4.3e-68 229.5 0.0 5e-68 229.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40130.1 - 3.5e-31 108.4 0.1 5e-31 107.9 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC40130.1 - 3.6e-06 26.5 0.1 0.0071 15.7 0.0 2.3 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.22 EGC40130.1 - 3.4e-05 23.5 0.2 5.2e-05 22.9 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.14 EGC40130.1 - 0.16 11.3 0.1 0.26 10.6 0.1 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family IF-2B PF01008.17 EGC40131.1 - 1.1e-74 251.2 0.0 1.3e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2963 PF11178.8 EGC40132.1 - 0.051 13.3 0.0 0.8 9.5 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) Dickkopf_N PF04706.12 EGC40132.1 - 0.075 13.5 0.9 0.075 13.5 0.9 6.1 5 2 1 6 6 6 0 Dickkopf N-terminal cysteine-rich region FNIP PF05725.12 EGC40133.1 - 8.9e-90 294.7 39.3 1.8e-12 47.2 0.4 8.3 6 2 1 8 8 8 8 FNIP Repeat DUF212 PF02681.14 EGC40133.1 - 0.009 16.1 0.1 2.7 8.1 0.0 4.3 3 3 3 6 6 6 1 Divergent PAP2 family DUF1769 PF08588.10 EGC40133.1 - 0.015 15.5 13.2 48 4.3 0.1 7.9 8 2 2 10 10 10 0 Protein of unknown function (DUF1769) Coiled PF05710.12 EGC40134.1 - 0.037 14.8 16.2 0.056 14.3 16.2 1.3 1 1 0 1 1 1 0 Coiled coil 14-3-3 PF00244.20 EGC40135.1 - 0.019 14.5 0.0 0.02 14.4 0.0 1.0 1 0 0 1 1 1 0 14-3-3 protein PhoLip_ATPase_C PF16212.5 EGC40136.1 - 9.9e-57 192.5 27.5 9.9e-57 192.5 27.5 2.4 2 0 0 2 2 2 1 Phospholipid-translocating P-type ATPase C-terminal PhoLip_ATPase_N PF16209.5 EGC40136.1 - 4.4e-26 90.4 0.5 4.4e-26 90.4 0.5 3.1 3 0 0 3 3 3 1 Phospholipid-translocating ATPase N-terminal E1-E2_ATPase PF00122.20 EGC40136.1 - 8.6e-15 54.7 0.0 2.9e-14 53.0 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.26 EGC40136.1 - 6.6e-13 49.4 0.2 2.9e-06 27.7 0.1 3.4 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase PF13246.6 EGC40136.1 - 1.5e-10 41.0 0.1 5.4e-10 39.2 0.1 2.0 1 0 0 1 1 1 1 Cation transport ATPase (P-type) ZYG-11_interact PF05884.12 EGC40136.1 - 0.034 13.6 6.1 0.069 12.6 0.2 2.5 2 0 0 2 2 2 0 Interactor of ZYG-11 Hydrolase_6 PF13344.6 EGC40136.1 - 0.26 11.4 1.7 0.48 10.6 0.0 2.3 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase PseudoU_synth_1 PF01416.20 EGC40137.1 - 1.7e-32 112.1 0.0 5.4e-24 84.7 0.0 2.5 2 1 1 3 3 3 2 tRNA pseudouridine synthase Sod_Cu PF00080.20 EGC40138.1 - 1.2e-29 103.3 1.8 8.6e-26 90.8 3.2 2.5 2 1 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Serglycin PF04360.12 EGC40138.1 - 0.26 11.2 4.7 0.51 10.3 4.7 1.4 1 0 0 1 1 1 0 Serglycin AF-4 PF05110.13 EGC40138.1 - 2.9 5.9 8.2 3.8 5.5 8.2 1.0 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF507 PF04368.13 EGC40139.1 - 0.0057 16.6 6.0 0.0077 16.2 6.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF507) DASH_Ask1 PF08655.10 EGC40139.1 - 0.0095 15.8 3.4 0.014 15.3 2.3 1.8 2 0 0 2 2 2 1 DASH complex subunit Ask1 DUF2278 PF10042.9 EGC40139.1 - 0.01 15.8 0.1 0.013 15.5 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) MinE PF03776.14 EGC40139.1 - 0.12 12.4 4.4 0.18 11.8 1.2 2.2 1 1 1 2 2 2 0 Septum formation topological specificity factor MinE DUF1845 PF08900.11 EGC40139.1 - 0.13 12.0 0.4 0.17 11.6 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) Malate_synthase PF01274.22 EGC40140.1 - 1.9e-90 303.6 0.0 4.6e-90 302.4 0.0 1.5 1 1 0 1 1 1 1 Malate synthase S_100 PF01023.19 EGC40140.1 - 0.03 14.0 1.8 0.1 12.3 1.8 1.9 1 0 0 1 1 1 0 S-100/ICaBP type calcium binding domain TSNR_N PF04705.12 EGC40140.1 - 0.14 12.3 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus EGF_2 PF07974.13 EGC40141.1 - 0.36 11.2 10.9 0.68 10.4 10.9 1.4 1 0 0 1 1 1 0 EGF-like domain Minor_capsid_3 PF12691.7 EGC40142.1 - 0.034 14.5 0.0 0.034 14.5 0.0 2.9 4 0 0 4 4 4 0 Minor capsid protein from bacteriophage HAT PF02184.16 EGC40143.1 - 2e-21 75.6 55.9 1.6e-10 40.8 0.3 14.4 14 2 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.6 EGC40143.1 - 2.8e-20 71.3 2.9 0.26 12.2 0.0 9.9 4 3 6 10 10 10 5 Tetratricopeptide repeat TPR_19 PF14559.6 EGC40143.1 - 8.2e-17 61.5 0.0 0.02 15.4 0.0 6.8 7 0 0 7 7 6 5 Tetratricopeptide repeat Suf PF05843.14 EGC40143.1 - 2.9e-16 60.3 36.3 1.3e-06 28.6 3.0 8.2 2 1 5 7 7 7 5 Suppressor of forked protein (Suf) TPR_15 PF13429.6 EGC40143.1 - 6.5e-09 35.4 10.3 0.00029 20.1 0.0 4.5 2 2 1 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.6 EGC40143.1 - 8.8e-08 32.7 0.0 19 6.0 0.0 7.1 7 2 0 7 7 7 0 Tetratricopeptide repeat TPR_6 PF13174.6 EGC40143.1 - 2.1e-07 31.1 12.7 16 6.4 0.2 9.5 10 1 1 11 11 10 0 Tetratricopeptide repeat TPR_8 PF13181.6 EGC40143.1 - 3.6e-07 29.9 9.2 0.35 11.2 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_12 PF13424.6 EGC40143.1 - 7.1e-07 29.4 9.1 0.076 13.3 0.3 6.8 7 1 0 7 7 6 1 Tetratricopeptide repeat TPR_2 PF07719.17 EGC40143.1 - 6.4e-06 25.9 21.7 7.8 6.9 0.0 9.5 12 0 0 12 12 9 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGC40143.1 - 1.4e-05 25.1 27.5 0.19 11.7 3.8 6.8 5 1 2 7 7 7 3 Mad3/BUB1 homology region 1 TPR_17 PF13431.6 EGC40143.1 - 1.6e-05 25.0 1.2 0.47 10.9 0.0 4.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC40143.1 - 0.00077 19.6 0.1 2.3 8.4 0.0 3.9 3 2 1 4 4 4 1 Tetratricopeptide repeat TPPII_N PF12583.8 EGC40143.1 - 0.0016 19.0 0.1 2.7 8.6 0.0 3.5 4 0 0 4 4 3 1 Tripeptidyl peptidase II N terminal U3_assoc_6 PF08640.11 EGC40143.1 - 0.0036 17.4 25.1 0.011 15.8 0.7 7.3 4 4 3 7 7 7 1 U3 small nucleolar RNA-associated protein 6 TPR_10 PF13374.6 EGC40143.1 - 0.011 15.6 10.8 1.8 8.5 0.3 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_7 PF13176.6 EGC40143.1 - 0.027 14.5 4.4 8.2 6.7 0.1 5.6 6 0 0 6 6 5 0 Tetratricopeptide repeat TAtT PF16811.5 EGC40143.1 - 0.17 11.1 4.3 9.2 5.5 0.3 3.9 3 2 1 4 4 4 0 TRAP transporter T-component TPR_1 PF00515.28 EGC40143.1 - 0.3 11.0 4.7 39 4.3 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.26 EGC40144.1 - 4.6e-16 59.1 0.0 2.7e-08 33.8 0.0 2.9 2 0 0 2 2 2 2 Glycosyl transferase family 2 ETRAMP PF09716.10 EGC40145.1 - 0.0083 16.2 6.7 0.0083 16.2 6.7 2.4 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) Orf78 PF06024.12 EGC40145.1 - 0.011 16.0 3.6 0.011 16.0 3.6 1.9 2 0 0 2 2 2 0 Orf78 (ac78) Sigma_reg_N PF13800.6 EGC40145.1 - 0.014 15.6 4.0 0.014 15.6 4.0 2.0 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CD34_antigen PF06365.12 EGC40145.1 - 0.025 14.2 1.0 0.046 13.3 1.0 1.4 1 0 0 1 1 1 0 CD34/Podocalyxin family SPX PF03105.19 EGC40146.1 - 0.012 15.5 13.4 0.015 15.2 13.4 1.2 1 0 0 1 1 1 0 SPX domain Q_salvage PF10343.9 EGC40146.1 - 0.036 13.6 0.1 0.095 12.3 0.0 1.6 2 0 0 2 2 2 0 Potential Queuosine, Q, salvage protein family Tmemb_cc2 PF10267.9 EGC40146.1 - 2.6 7.1 8.5 3.6 6.6 8.5 1.2 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Coagulin PF02035.15 EGC40147.1 - 0.037 13.9 0.3 0.058 13.3 0.2 1.3 1 1 0 1 1 1 0 Coagulin DUF2852 PF11014.8 EGC40148.1 - 0.097 12.8 0.0 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) Pho88 PF10032.9 EGC40148.1 - 0.1 11.8 0.0 0.14 11.4 0.0 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) CBM49 PF09478.10 EGC40149.1 - 1.1e-15 57.7 3.6 1.5e-15 57.3 3.6 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.10 EGC40150.1 - 8.8e-09 35.6 0.6 1.6e-08 34.7 0.6 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 eIF-3c_N PF05470.12 EGC40151.1 - 3.7e-129 431.7 21.5 3.7e-129 431.7 21.5 2.0 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.27 EGC40151.1 - 6e-11 42.8 0.2 5.7e-10 39.6 0.1 2.6 2 0 0 2 2 2 1 PCI domain tRNA-synt_1g PF09334.11 EGC40152.1 - 2.5e-141 471.0 3.3 8.3e-141 469.2 3.3 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.20 EGC40152.1 - 3e-21 75.3 0.1 5.4e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.22 EGC40152.1 - 4.1e-09 35.2 1.9 8.3e-05 21.0 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.13 EGC40152.1 - 1.7e-06 28.1 0.3 3.8e-06 26.9 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.19 EGC40152.1 - 0.045 13.1 0.1 0.11 11.9 0.1 1.6 1 0 0 1 1 1 0 tRNA synthetases class I (C) catalytic domain DZR PF12773.7 EGC40152.1 - 6.6 6.8 7.7 16 5.6 7.7 1.6 1 0 0 1 1 1 0 Double zinc ribbon His_Phos_1 PF00300.22 EGC40153.1 - 1.1e-28 100.3 0.8 1.8e-28 99.6 0.8 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Helicase_C_3 PF13625.6 EGC40153.1 - 0.12 12.6 0.0 0.27 11.4 0.0 1.6 1 1 0 1 1 1 0 Helicase conserved C-terminal domain Menin PF05053.13 EGC40154.1 - 0.55 8.5 6.8 0.79 8.0 6.8 1.2 1 0 0 1 1 1 0 Menin SMYLE_N PF18615.1 EGC40154.1 - 2.2 7.7 5.0 4.4 6.8 5.0 1.5 1 0 0 1 1 1 0 Short myomegalin-like EB1 binding proteins, N-terminal domain SR-25 PF10500.9 EGC40154.1 - 5.3 6.6 10.6 10 5.6 10.6 1.5 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Mac PF12464.8 EGC40156.1 - 2e-15 56.8 0.0 2.9e-15 56.2 0.0 1.3 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep_2 PF14602.6 EGC40156.1 - 3.4e-11 42.7 16.1 3.4e-09 36.3 5.9 3.5 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase Hexapep PF00132.24 EGC40156.1 - 2.3e-10 39.8 12.7 3.5e-09 36.0 5.4 3.3 4 0 0 4 4 4 2 Bacterial transferase hexapeptide (six repeats) COesterase PF00135.28 EGC40157.1 - 3.9e-114 382.4 0.0 4.8e-114 382.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.13 EGC40157.1 - 3.7e-06 26.9 0.0 9.3e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF192 PF02643.15 EGC40157.1 - 0.052 13.7 0.0 0.11 12.7 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Peptidase_S9 PF00326.21 EGC40157.1 - 0.097 12.1 0.1 0.16 11.4 0.1 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family X8 PF07983.13 EGC40157.1 - 0.11 13.2 0.2 0.27 11.9 0.2 1.6 1 0 0 1 1 1 0 X8 domain DUF2157 PF09925.9 EGC40158.1 - 0.042 13.7 9.2 0.055 13.2 5.2 2.4 1 1 1 2 2 2 0 Predicted membrane protein (DUF2157) MCM PF00493.23 EGC40160.1 - 3.8e-87 291.1 0.0 5.5e-87 290.5 0.0 1.2 1 0 0 1 1 1 1 MCM P-loop domain MCM_lid PF17855.1 EGC40160.1 - 2e-27 95.5 0.5 4e-27 94.5 0.5 1.5 1 0 0 1 1 1 1 MCM AAA-lid domain MCM_OB PF17207.3 EGC40160.1 - 1.1e-25 89.9 0.6 2.1e-25 89.0 0.6 1.5 1 0 0 1 1 1 1 MCM OB domain Mg_chelatase PF01078.21 EGC40160.1 - 7.4e-10 38.6 0.1 1e-07 31.5 0.0 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.14 EGC40160.1 - 8.6e-09 35.5 0.0 1.9e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.11 EGC40160.1 - 3.9e-05 23.5 0.0 0.00013 21.8 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.26 EGC40160.1 - 0.0003 20.6 0.0 0.00089 19.0 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_16 PF13191.6 EGC40160.1 - 0.0038 17.6 0.1 0.026 14.9 0.0 2.3 1 1 0 2 2 2 1 AAA ATPase domain ABC_sub_bind PF04392.12 EGC40160.1 - 0.045 13.0 0.1 0.076 12.2 0.1 1.3 1 0 0 1 1 1 0 ABC transporter substrate binding protein AAA_19 PF13245.6 EGC40160.1 - 0.081 13.3 0.0 11 6.4 0.0 2.5 2 0 0 2 2 2 0 AAA domain RWP-RK PF02042.15 EGC40160.1 - 0.093 12.7 0.1 0.2 11.6 0.1 1.5 1 0 0 1 1 1 0 RWP-RK domain cobW PF02492.19 EGC40160.1 - 0.12 11.9 0.0 0.28 10.7 0.0 1.7 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF2959 PF11172.8 EGC40160.1 - 0.22 11.7 3.5 0.09 12.9 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2959) APG12 PF04110.13 EGC40161.1 - 7.7e-28 96.7 0.2 1e-27 96.4 0.2 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.16 EGC40161.1 - 6.1e-07 29.6 0.0 7.3e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Pkinase_Tyr PF07714.17 EGC40162.1 - 6.9e-60 202.5 0.0 9.3e-60 202.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC40162.1 - 1.6e-47 162.1 0.0 2.4e-47 161.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.24 EGC40162.1 - 4.7e-16 58.6 0.1 9.2e-16 57.7 0.1 1.5 1 0 0 1 1 1 1 SH2 domain Haspin_kinase PF12330.8 EGC40162.1 - 5.7e-05 22.2 0.2 0.00085 18.4 0.0 2.2 2 0 0 2 2 2 1 Haspin like kinase domain APH PF01636.23 EGC40162.1 - 8.1e-05 22.7 0.1 0.00022 21.2 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family EF-hand_12 PF17901.1 EGC40162.1 - 0.02 15.3 0.1 0.07 13.6 0.0 1.9 2 0 0 2 2 2 0 EF-hand fold domain ABC1 PF03109.16 EGC40162.1 - 0.062 13.5 0.0 0.14 12.3 0.0 1.6 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.25 EGC40163.1 - 6.8e-53 179.7 0.0 1.1e-52 179.0 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40163.1 - 8.4e-35 120.3 0.0 1.4e-34 119.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC40163.1 - 0.00049 19.0 0.0 0.00049 19.0 0.0 2.0 2 0 0 2 2 2 1 Fungal protein kinase Kinase-like PF14531.6 EGC40163.1 - 0.0041 16.5 0.0 0.011 15.1 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.14 EGC40163.1 - 0.007 15.7 0.0 0.013 14.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Rad50_zn_hook PF04423.14 EGC40163.1 - 0.0079 16.0 1.0 0.021 14.7 1.0 1.7 1 0 0 1 1 1 1 Rad50 zinc hook motif APH PF01636.23 EGC40163.1 - 0.15 12.0 0.0 0.26 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF5030 PF16433.5 EGC40164.1 - 0.042 13.2 0.3 0.083 12.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF5030) DHHC PF01529.20 EGC40165.1 - 7.9e-37 126.4 8.5 7.9e-37 126.4 8.5 3.1 1 1 1 2 2 1 1 DHHC palmitoyltransferase UPF0242 PF06785.11 EGC40165.1 - 0.00061 19.9 0.5 0.00095 19.3 0.5 1.3 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0242) N-terminus Ni_hydr_CYTB PF01292.20 EGC40165.1 - 0.00064 19.4 0.1 0.00064 19.4 0.1 2.2 2 1 0 2 2 2 1 Prokaryotic cytochrome b561 Peptidase_S49_N PF08496.10 EGC40165.1 - 0.0011 19.0 3.6 0.0011 19.0 3.6 1.7 2 0 0 2 2 1 1 Peptidase family S49 N-terminal Neur_chan_memb PF02932.16 EGC40165.1 - 0.025 14.6 0.2 0.025 14.6 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Connexin PF00029.19 EGC40165.1 - 0.032 14.0 0.8 0.032 14.0 0.8 2.5 3 1 0 3 3 3 0 Connexin Reticulon PF02453.17 EGC40165.1 - 0.041 13.8 4.4 0.12 12.3 0.0 2.9 3 0 0 3 3 3 0 Reticulon EPL1 PF10513.9 EGC40165.1 - 0.11 12.8 10.7 0.19 12.1 10.7 1.2 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3573 PF12097.8 EGC40165.1 - 0.13 11.1 2.0 0.18 10.6 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF4834 PF16118.5 EGC40165.1 - 0.41 11.6 9.2 0.071 14.1 1.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4834) TMEM132D_C PF15706.5 EGC40165.1 - 0.94 9.3 8.1 8.1 6.3 8.1 2.6 1 1 0 1 1 1 0 Mature oligodendrocyte transmembrane protein, TMEM132D, C-term CPSF100_C PF13299.6 EGC40165.1 - 1.3 9.2 8.3 1.9 8.6 8.3 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal CDC45 PF02724.14 EGC40165.1 - 9.2 4.4 11.0 12 4.0 11.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Evr1_Alr PF04777.13 EGC40166.1 - 4.5e-11 43.1 2.3 3e-10 40.5 0.4 2.7 2 0 0 2 2 2 1 Erv1 / Alr family CRA PF06589.11 EGC40167.1 - 0.088 12.9 8.0 0.26 11.4 8.0 1.8 1 0 0 1 1 1 0 Circumsporozoite-related antigen (CRA) EGF_2 PF07974.13 EGC40167.1 - 0.1 13.0 14.8 0.33 11.3 14.8 2.0 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.12 EGC40168.1 - 5.4e-49 164.1 58.6 2.8e-05 24.2 2.2 12.7 10 3 2 13 13 13 11 FNIP Repeat AAA_3 PF07726.11 EGC40168.1 - 0.011 15.6 1.6 47 3.8 0.0 5.2 2 2 5 7 7 7 0 ATPase family associated with various cellular activities (AAA) zf-B_box PF00643.24 EGC40168.1 - 0.022 14.9 11.9 0.039 14.1 11.9 1.4 1 0 0 1 1 1 0 B-box zinc finger Tfb2_C PF18307.1 EGC40168.1 - 0.083 13.3 0.1 16 6.0 0.0 2.7 2 0 0 2 2 2 0 Transcription factor Tfb2 (p52) C-terminal domain Suf PF05843.14 EGC40169.1 - 8.7e-12 45.6 40.5 9.6e-08 32.3 6.1 5.1 1 1 1 3 3 3 3 Suppressor of forked protein (Suf) TPR_14 PF13428.6 EGC40169.1 - 0.0046 17.7 0.0 5 8.2 0.0 4.6 3 1 2 5 5 5 1 Tetratricopeptide repeat RepA_C PF04796.12 EGC40169.1 - 0.032 14.3 1.2 0.23 11.5 0.3 2.4 2 0 0 2 2 2 0 Plasmid encoded RepA protein TPR_16 PF13432.6 EGC40169.1 - 0.081 13.6 0.0 0.19 12.4 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.12 EGC40169.1 - 0.088 12.8 15.9 4.4 7.3 0.0 5.8 5 1 1 6 6 6 0 Mad3/BUB1 homology region 1 TPR_2 PF07719.17 EGC40169.1 - 0.1 12.7 0.4 2.7 8.3 0.2 3.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_15 PF13429.6 EGC40169.1 - 0.14 11.3 0.1 3.8 6.6 0.0 2.6 2 1 0 2 2 2 0 Tetratricopeptide repeat Pex14_N PF04695.13 EGC40169.1 - 4.2 8.0 13.3 9.8 6.8 13.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_S9 PF00326.21 EGC40170.1 - 9.4e-09 35.0 0.0 1.7e-08 34.2 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Esterase PF00756.20 EGC40170.1 - 0.00034 20.3 0.0 0.00075 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.11 EGC40170.1 - 0.017 14.5 0.4 0.036 13.4 0.0 1.7 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) Hydrolase_4 PF12146.8 EGC40170.1 - 0.023 13.9 0.1 0.63 9.3 0.1 2.2 1 1 0 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC40170.1 - 0.043 14.4 0.0 0.086 13.4 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Acyl-CoA_dh_1 PF00441.24 EGC40171.1 - 1.5e-45 155.0 0.2 2.4e-45 154.4 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.16 EGC40171.1 - 1.3e-28 99.9 0.0 3.7e-28 98.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.19 EGC40171.1 - 1.6e-25 89.1 0.0 2.9e-25 88.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.11 EGC40171.1 - 1.6e-21 77.0 0.0 2.3e-21 76.5 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain TFIIA PF03153.13 EGC40172.1 - 0.067 13.2 68.6 0.13 12.2 31.6 2.6 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit EF-hand_7 PF13499.6 EGC40172.1 - 0.072 13.6 0.1 0.18 12.3 0.1 1.7 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_8 PF13833.6 EGC40172.1 - 0.11 12.4 0.3 0.33 10.8 0.3 1.8 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_6 PF13405.6 EGC40172.1 - 0.32 11.0 2.0 1.8 8.7 2.0 2.4 1 0 0 1 1 1 0 EF-hand domain DUF3439 PF11921.8 EGC40172.1 - 0.54 10.2 16.6 0.049 13.6 9.3 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF853 PF05872.12 EGC40172.1 - 0.55 8.8 6.3 1.1 7.7 6.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Brr6_like_C_C PF10104.9 EGC40173.1 - 0.0095 15.7 1.0 0.013 15.3 1.0 1.2 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain RSN1_7TM PF02714.15 EGC40174.1 - 3.8e-72 242.9 21.4 3.8e-72 242.9 21.4 2.3 3 0 0 3 3 3 1 Calcium-dependent channel, 7TM region, putative phosphate RSN1_TM PF13967.6 EGC40174.1 - 2.6e-34 118.2 5.7 2.6e-34 118.2 5.7 3.2 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport PHM7_cyt PF14703.6 EGC40174.1 - 6e-29 101.5 0.6 2.9e-28 99.3 0.6 1.9 1 1 0 1 1 1 1 Cytosolic domain of 10TM putative phosphate transporter AIRC PF00731.20 EGC40175.1 - 2e-61 205.9 0.9 3.5e-61 205.1 0.9 1.4 1 0 0 1 1 1 1 AIR carboxylase ATP-grasp PF02222.22 EGC40175.1 - 1.5e-53 180.8 0.1 3.9e-53 179.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain SAICAR_synt PF01259.18 EGC40175.1 - 1.2e-50 172.5 0.0 2.2e-50 171.6 0.0 1.4 1 0 0 1 1 1 1 SAICAR synthetase PurK_C PF17769.1 EGC40175.1 - 5.2e-14 51.7 0.2 1.2e-13 50.5 0.2 1.6 1 0 0 1 1 1 1 Phosphoribosylaminoimidazole carboxylase C-terminal domain GARS_A PF01071.19 EGC40175.1 - 1.6e-05 24.8 0.1 3.4e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.17 EGC40175.1 - 2.6e-05 23.8 0.0 5.2e-05 22.8 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain PALP PF00291.25 EGC40175.1 - 0.014 14.9 0.0 0.014 14.9 0.0 1.7 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme IBR PF01485.21 EGC40176.1 - 1.2e-17 63.8 11.3 2.8e-14 53.1 5.4 2.1 2 0 0 2 2 2 2 IBR domain, a half RING-finger domain Rad50_zn_hook PF04423.14 EGC40176.1 - 0.12 12.2 0.2 0.12 12.2 0.2 3.0 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-piccolo PF05715.13 EGC40176.1 - 0.35 11.0 7.4 0.58 10.3 0.0 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger C1_4 PF07975.12 EGC40176.1 - 1.7 8.9 13.8 0.14 12.4 5.4 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3039 PF11238.8 EGC40176.1 - 1.9 8.3 7.1 4 7.3 2.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-AN1 PF01428.16 EGC40176.1 - 2.1 8.6 12.7 1.3 9.3 7.8 2.4 2 1 0 2 2 2 0 AN1-like Zinc finger Sec1 PF00995.23 EGC40177.1 - 4.7e-115 386.0 9.8 5.3e-115 385.8 9.8 1.0 1 0 0 1 1 1 1 Sec1 family GIY-YIG PF01541.24 EGC40177.1 - 0.053 13.8 0.5 0.56 10.5 0.3 2.7 2 0 0 2 2 2 0 GIY-YIG catalytic domain T3SS_needle_F PF09392.10 EGC40177.1 - 0.065 13.4 0.2 0.18 12.0 0.2 1.7 1 0 0 1 1 1 0 Type III secretion needle MxiH, YscF, SsaG, EprI, PscF, EscF adh_short PF00106.25 EGC40178.1 - 1.2e-06 28.2 0.0 2.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC40178.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGC40179.1 - 1.4e-06 27.9 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Cript PF10235.9 EGC40179.1 - 0.0023 18.5 1.9 0.0023 18.5 1.9 3.0 4 0 0 4 4 4 1 Microtubule-associated protein CRIPT adh_short_C2 PF13561.6 EGC40179.1 - 0.011 15.3 0.0 0.018 14.6 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC40179.1 - 0.21 11.4 0.0 0.36 10.7 0.0 1.3 1 0 0 1 1 1 0 KR domain E1_dh PF00676.20 EGC40180.1 - 2.7e-106 354.9 0.2 3.2e-106 354.6 0.2 1.0 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.21 EGC40180.1 - 3.8e-05 23.5 1.2 7.1e-05 22.6 1.2 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.6 EGC40180.1 - 0.00079 18.7 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase mCpol PF18182.1 EGC40180.1 - 0.067 13.5 0.0 0.15 12.4 0.0 1.6 1 0 0 1 1 1 0 minimal CRISPR polymerase domain Pkinase PF00069.25 EGC40181.1 - 7.1e-46 156.7 0.0 1.9e-45 155.3 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40181.1 - 3e-36 125.1 0.0 5.2e-36 124.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGEF PF00621.20 EGC40181.1 - 2.2e-35 122.6 1.6 2.2e-35 122.6 1.6 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.29 EGC40181.1 - 5.6e-08 33.2 0.0 5.3e-07 30.1 0.0 2.8 2 1 0 2 2 2 1 PH domain PH_16 PF17838.1 EGC40181.1 - 7.5e-06 25.8 2.8 0.0053 16.6 0.0 2.9 3 0 0 3 3 3 2 PH domain IQ_SEC7_PH PF16453.5 EGC40181.1 - 2.9e-05 24.0 0.0 0.00011 22.1 0.0 2.0 1 1 0 1 1 1 1 PH domain Pkinase_fungal PF17667.1 EGC40181.1 - 0.00011 21.1 0.0 0.00031 19.6 0.0 1.7 1 0 0 1 1 1 1 Fungal protein kinase PH_13 PF16652.5 EGC40181.1 - 0.00078 19.3 3.0 0.26 11.1 0.1 2.6 2 0 0 2 2 2 2 Pleckstrin homology domain KASH_CCD PF14662.6 EGC40181.1 - 0.0019 18.1 3.7 0.0061 16.4 0.5 3.0 3 0 0 3 3 3 1 Coiled-coil region of CCDC155 or KASH APH PF01636.23 EGC40181.1 - 0.0031 17.5 0.0 0.13 12.1 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family TACC_C PF05010.14 EGC40181.1 - 0.031 14.1 0.1 0.031 14.1 0.1 2.5 3 0 0 3 3 3 0 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Peptidase_M10_C PF08548.11 EGC40181.1 - 0.071 13.0 2.2 0.27 11.1 0.9 2.4 2 0 0 2 2 2 0 Peptidase M10 serralysin C terminal PH_11 PF15413.6 EGC40181.1 - 0.96 9.9 0.0 0.96 9.9 0.0 3.2 3 1 1 4 4 4 0 Pleckstrin homology domain bZIP_1 PF00170.21 EGC40181.1 - 1.2 9.2 4.2 1.7 8.8 0.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor TIG PF01833.24 EGC40183.1 - 0.00024 21.1 1.6 0.00024 21.1 1.6 6.9 7 1 1 8 8 8 3 IPT/TIG domain BcsB PF03170.13 EGC40183.1 - 0.058 11.8 1.0 1.2 7.4 0.1 2.2 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit DUF1146 PF06612.11 EGC40184.1 - 0.048 13.7 0.2 0.067 13.2 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1146) YL1_C PF08265.11 EGC40184.1 - 0.069 12.9 0.0 0.14 12.0 0.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain DUF2368 PF10166.9 EGC40184.1 - 0.19 11.4 0.1 0.24 11.0 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2368) TIG PF01833.24 EGC40185.1 - 2e-07 31.0 38.7 1.6e-05 24.9 2.0 6.3 7 1 0 7 7 7 3 IPT/TIG domain BcsB PF03170.13 EGC40185.1 - 0.39 9.0 1.9 0.67 8.2 0.2 2.0 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit ubiquitin PF00240.23 EGC40186.1 - 9.2e-19 67.0 2.5 1.1e-18 66.7 0.9 1.8 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.8 EGC40186.1 - 1.5e-09 37.6 0.7 2.5e-09 36.8 0.7 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3990 PF13151.6 EGC40186.1 - 0.0034 17.1 0.0 0.0069 16.1 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) PARP PF00644.20 EGC40186.1 - 0.015 14.9 0.0 0.025 14.2 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain SUN PF03856.13 EGC40186.1 - 0.058 12.8 0.2 0.13 11.7 0.1 1.6 1 1 1 2 2 2 0 Beta-glucosidase (SUN family) TIG PF01833.24 EGC40187.1 - 0.00075 19.5 2.2 0.00075 19.5 2.2 2.5 1 1 2 3 3 3 1 IPT/TIG domain TIG PF01833.24 EGC40189.1 - 0.0061 16.6 1.7 0.0061 16.6 1.7 6.6 4 2 3 7 7 7 3 IPT/TIG domain DUF4179 PF13786.6 EGC40189.1 - 1.1 9.8 5.1 2.4 8.7 0.1 3.7 4 0 0 4 4 4 0 Domain of unknown function (DUF4179) TIG PF01833.24 EGC40190.1 - 1.4e-05 25.1 41.0 0.00016 21.7 1.7 6.9 4 1 2 7 7 7 4 IPT/TIG domain Nsp1 PF11501.8 EGC40190.1 - 0.042 13.9 0.0 0.082 13.0 0.0 1.4 1 0 0 1 1 1 0 Non structural protein Nsp1 TIG PF01833.24 EGC40191.1 - 0.0002 21.4 2.1 0.0002 21.4 2.1 7.7 7 1 1 8 8 8 3 IPT/TIG domain DUF3990 PF13151.6 EGC40191.1 - 0.025 14.2 0.2 0.14 11.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3990) Myco_arth_vir_N PF09610.10 EGC40191.1 - 2.2 8.4 8.4 8.3 6.6 0.3 2.5 2 0 0 2 2 2 0 Mycoplasma virulence signal region (Myco_arth_vir_N) DNA_pol_E_B PF04042.16 EGC40192.1 - 7.1e-30 103.9 5.8 1.4e-29 103.0 5.8 1.5 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B DUF150_C PF17384.2 EGC40192.1 - 0.0031 17.6 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 RimP C-terminal SH3 domain eIF-3c_N PF05470.12 EGC40192.1 - 0.091 11.1 5.8 0.15 10.4 5.8 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Complex1_LYR PF05347.15 EGC40193.1 - 9.1e-09 35.2 0.4 1.3e-08 34.7 0.4 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) DUF4127 PF13552.6 EGC40193.1 - 0.0027 16.4 0.6 0.003 16.2 0.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF4127) Phage_connect_1 PF05135.13 EGC40193.1 - 0.025 15.1 0.4 0.046 14.2 0.3 1.6 1 1 0 1 1 1 0 Phage gp6-like head-tail connector protein Sortilin_C PF15901.5 EGC40195.1 - 1.6e-16 61.1 12.3 3.1e-16 60.2 12.3 1.4 1 0 0 1 1 1 1 Sortilin, neurotensin receptor 3, C-terminal BNR PF02012.20 EGC40195.1 - 0.41 10.8 7.5 2.3 8.5 0.6 4.2 3 0 0 3 3 3 0 BNR/Asp-box repeat UPF0220 PF05255.11 EGC40196.1 - 8.4e-31 106.8 1.4 9.8e-31 106.5 1.4 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) Dicty_CTDC PF00526.18 EGC40197.1 - 0.00016 21.5 3.9 0.00016 21.5 3.9 5.5 6 1 0 6 6 6 2 Dictyostelium (slime mold) repeat IF4E PF01652.18 EGC40198.1 - 9.3e-38 129.5 0.2 1.2e-37 129.1 0.2 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TIG PF01833.24 EGC40199.1 - 0.00012 22.1 4.0 0.0012 18.9 1.1 2.3 2 0 0 2 2 2 2 IPT/TIG domain TIG PF01833.24 EGC40200.1 - 2.7e-22 78.7 37.1 0.0003 20.8 0.2 7.5 7 0 0 7 7 7 6 IPT/TIG domain RHD3 PF05879.12 EGC40202.1 - 7.8e-183 609.6 19.7 1.2e-182 608.9 19.7 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.23 EGC40202.1 - 5.2e-05 23.3 0.4 0.00026 21.0 0.0 2.5 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.23 EGC40202.1 - 0.0049 16.9 0.0 0.0049 16.9 0.0 3.7 3 1 0 3 3 3 1 Dynamin family RNA_pol_RpbG PF16992.5 EGC40202.1 - 0.031 14.3 0.7 0.081 13.0 0.4 1.8 1 1 0 1 1 1 0 DNA-directed RNA polymerase, subunit G AAA_28 PF13521.6 EGC40202.1 - 0.042 14.1 0.1 0.12 12.7 0.1 1.8 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.6 EGC40202.1 - 0.41 10.9 2.5 13 6.0 0.0 3.3 3 1 0 3 3 3 0 AAA domain YtxH PF12732.7 EGC40202.1 - 0.52 10.9 8.2 4 8.0 0.4 4.2 3 2 1 4 4 4 0 YtxH-like protein ABC_tran PF00005.27 EGC40202.1 - 0.75 10.3 0.0 0.75 10.3 0.0 4.1 4 0 0 4 4 4 0 ABC transporter SIR2 PF02146.17 EGC40203.1 - 1.2e-40 139.3 0.0 3.4e-40 137.9 0.0 1.8 1 0 0 1 1 1 1 Sir2 family Ank_2 PF12796.7 EGC40203.1 - 4.7e-34 116.8 20.5 1.7e-10 41.3 0.2 5.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC40203.1 - 9.3e-30 102.6 12.1 1.4e-07 31.9 0.1 7.4 3 3 6 9 9 9 7 Ankyrin repeats (many copies) Ank PF00023.30 EGC40203.1 - 3.5e-28 96.8 15.8 0.00056 20.2 0.0 9.4 8 1 1 9 9 9 7 Ankyrin repeat Ank_3 PF13606.6 EGC40203.1 - 4e-27 91.3 10.1 0.0051 17.2 0.0 9.8 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.6 EGC40203.1 - 5e-26 90.4 14.8 5e-08 33.1 0.6 6.6 3 2 3 6 6 6 6 Ankyrin repeats (many copies) DUF1378 PF07125.11 EGC40203.1 - 0.15 12.2 0.1 0.32 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) InPase PF18823.1 EGC40204.1 - 0.032 13.9 0.2 27 4.4 0.0 3.5 3 1 1 4 4 4 0 Inorganic Pyrophosphatase RNA_pol_Rpb4 PF03874.16 EGC40206.1 - 2.9e-20 72.8 4.2 6.2e-20 71.8 4.2 1.5 1 1 0 1 1 1 1 RNA polymerase Rpb4 Nse4_C PF08743.10 EGC40208.1 - 3.6e-20 72.0 0.2 3.6e-20 72.0 0.2 3.2 3 1 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.6 EGC40208.1 - 2e-09 37.4 1.8 4.3e-09 36.3 1.8 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DegV PF02645.16 EGC40208.1 - 0.028 13.8 0.8 1.2 8.4 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 Sec23_trunk PF04811.15 EGC40209.1 - 2.2e-64 217.3 0.1 4.7e-64 216.3 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_BS PF08033.12 EGC40209.1 - 1.2e-30 106.1 0.6 2.6e-30 105.0 0.6 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain Sec23_helical PF04815.15 EGC40209.1 - 1.1e-24 86.2 0.2 2.3e-24 85.2 0.2 1.6 1 0 0 1 1 1 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.15 EGC40209.1 - 5.3e-13 48.8 8.8 9.6e-13 48.0 8.8 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.22 EGC40209.1 - 1.9e-12 46.9 0.0 3.8e-12 45.9 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat Vps36-NZF-N PF16988.5 EGC40209.1 - 0.074 12.5 0.1 0.19 11.1 0.1 1.6 1 0 0 1 1 1 0 Vacuolar protein sorting 36 NZF-N zinc-finger domain TIG PF01833.24 EGC40211.1 - 0.0005 20.1 3.4 0.00093 19.2 0.1 2.8 1 1 3 4 4 4 1 IPT/TIG domain TIG PF01833.24 EGC40212.1 - 0.00061 19.8 0.8 0.00061 19.8 0.8 6.8 8 1 0 8 8 8 3 IPT/TIG domain TIG PF01833.24 EGC40213.1 - 1.7e-06 28.0 40.5 0.00015 21.8 1.7 7.1 5 2 2 7 7 7 3 IPT/TIG domain BcsB PF03170.13 EGC40213.1 - 0.14 10.5 0.8 0.31 9.4 0.0 1.7 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit TIG PF01833.24 EGC40214.1 - 2.4e-07 30.7 42.2 0.00031 20.8 1.5 7.4 6 1 1 7 7 7 3 IPT/TIG domain BcsB PF03170.13 EGC40214.1 - 0.61 8.4 3.0 3.7 5.8 0.3 2.2 2 0 0 2 2 2 0 Bacterial cellulose synthase subunit TIG PF01833.24 EGC40215.1 - 1e-06 28.7 41.6 0.00021 21.3 1.6 7.0 6 1 1 7 7 7 3 IPT/TIG domain BcsB PF03170.13 EGC40215.1 - 0.0068 14.8 1.7 0.32 9.3 0.1 2.2 2 0 0 2 2 2 2 Bacterial cellulose synthase subunit SdrD_B PF17210.3 EGC40216.1 - 0 3579.5 411.2 8.4e-21 74.3 0.5 78.1 77 2 0 77 77 77 77 SdrD B-like domain CarboxypepD_reg PF13620.6 EGC40216.1 - 0 1601.3 100.1 1.1e-07 32.0 0.1 78.5 77 1 1 78 78 78 76 Carboxypeptidase regulatory-like domain SpaA PF17802.1 EGC40216.1 - 1.8e-238 771.6 198.8 4.1e-05 23.8 0.4 75.7 75 1 1 76 76 76 61 Prealbumin-like fold domain bMG3 PF11974.8 EGC40216.1 - 1e-217 706.5 0.0 0.0027 17.7 0.0 70.7 72 0 0 72 72 72 50 Bacterial alpha-2-macroglobulin MG3 domain CarbopepD_reg_2 PF13715.6 EGC40216.1 - 7.5e-171 554.7 172.4 0.025 14.6 0.0 75.8 75 0 0 75 75 75 52 CarboxypepD_reg-like domain DUF2012 PF09430.10 EGC40216.1 - 9.9e-109 358.3 57.2 0.03 14.4 0.0 62.8 72 0 0 72 72 71 19 Protein of unknown function (DUF2012) MetallophosN PF16371.5 EGC40216.1 - 3.4e-65 216.3 202.7 0.18 12.1 0.1 65.3 73 0 0 73 73 72 21 N terminal of Calcineurin-like phosphoesterase Dioxygenase_C PF00775.21 EGC40216.1 - 5.3e-49 166.1 95.6 0.42 10.0 0.0 55.0 62 0 0 62 62 62 13 Dioxygenase Big_1 PF02369.16 EGC40216.1 - 9.4e-42 140.9 198.4 0.29 11.2 0.0 57.3 69 0 0 69 69 65 17 Bacterial Ig-like domain (group 1) Big_6 PF17936.1 EGC40216.1 - 4.1e-38 129.5 60.2 0.35 11.2 0.0 50.3 64 0 0 64 64 59 2 Bacterial Ig domain fn3_3 PF14686.6 EGC40216.1 - 3.6e-37 126.0 68.9 5.2 6.9 0.0 43.7 50 0 0 50 50 48 6 Polysaccharide lyase family 4, domain II TTR-52 PF01060.23 EGC40216.1 - 1.2e-32 112.4 33.3 3.4 8.4 0.0 43.1 59 0 0 59 59 47 1 Transthyretin-like family Interfer-bind PF09294.10 EGC40216.1 - 7.4e-29 100.1 23.6 2.3 8.6 0.0 37.3 44 1 1 45 45 42 2 Interferon-alpha/beta receptor, fibronectin type III DUF1416 PF07210.12 EGC40216.1 - 1.3e-20 73.1 0.0 15 5.6 0.0 17.1 18 0 0 18 18 18 0 Protein of unknown function (DUF1416) DUF2606 PF10794.9 EGC40216.1 - 0.027 14.3 0.1 18 5.1 0.0 6.1 5 0 0 5 5 5 0 Protein of unknown function (DUF2606) NKAIN PF05640.14 EGC40216.1 - 1.9 7.7 3.3 3e+02 0.5 0.0 5.4 8 0 0 8 8 8 0 Na,K-Atpase Interacting protein Pro_isomerase PF00160.21 EGC40217.1 - 2.1e-41 141.8 0.1 3.7e-41 141.0 0.1 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.22 EGC40217.1 - 2.5e-15 56.1 0.0 7.1e-15 54.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.22 EGC40218.1 - 6.8e-96 321.8 0.1 2e-95 320.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 EGF_2 PF07974.13 EGC40218.1 - 0.02 15.3 11.9 0.058 13.8 11.9 1.9 1 0 0 1 1 1 0 EGF-like domain EGF_Tenascin PF18720.1 EGC40218.1 - 3.1 8.0 7.1 8.3 6.6 7.1 1.8 1 0 0 1 1 1 0 Tenascin EGF domain TIG PF01833.24 EGC40219.1 - 0.0073 16.4 33.6 0.0079 16.3 0.3 6.0 5 1 1 6 6 6 4 IPT/TIG domain TIG PF01833.24 EGC40220.1 - 0.0003 20.8 1.2 0.0003 20.8 1.2 6.3 6 0 0 6 6 6 4 IPT/TIG domain Actin PF00022.19 EGC40221.1 - 4.1e-152 506.5 0.0 1.3e-151 504.8 0.0 1.6 1 1 0 1 1 1 1 Actin CTP_transf_like PF01467.26 EGC40222.1 - 2.9e-45 154.0 0.0 7e-26 91.1 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase-like FAD_syn PF06574.12 EGC40222.1 - 0.00013 21.9 5.2 0.88 9.4 0.2 3.8 2 2 0 2 2 2 2 FAD synthetase CoA_binding_3 PF13727.6 EGC40222.1 - 0.12 12.4 0.0 0.82 9.7 0.0 2.0 2 0 0 2 2 2 0 CoA-binding domain AAT PF03417.16 EGC40223.1 - 0.0067 16.1 0.0 0.015 15.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RmlD_sub_bind PF04321.17 EGC40223.1 - 0.18 10.8 0.0 0.27 10.3 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain CbiJ PF02571.14 EGC40223.1 - 0.2 11.1 0.0 0.37 10.2 0.0 1.4 1 0 0 1 1 1 0 Precorrin-6x reductase CbiJ/CobK DOMON PF03351.17 EGC40224.1 - 4.6e-25 88.2 0.5 7.1e-25 87.6 0.5 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.16 EGC40224.1 - 6.4e-13 49.0 15.7 6.4e-13 49.0 15.7 1.5 2 0 0 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.9 EGC40224.1 - 0.001 18.8 9.1 0.001 18.8 9.1 2.2 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) Zn_dep_PLPC PF00882.18 EGC40224.1 - 0.082 12.9 0.4 1.8 8.5 0.2 2.5 1 1 1 2 2 2 0 Zinc dependent phospholipase C 7TMR-DISM_7TM PF07695.11 EGC40224.1 - 2.3 8.1 27.7 2.1 8.2 15.6 2.4 1 1 1 2 2 2 0 7TM diverse intracellular signalling QueT PF06177.11 EGC40224.1 - 9.8 6.6 15.4 1.6 9.1 2.8 2.4 2 0 0 2 2 2 0 QueT transporter Pkinase PF00069.25 EGC40225.1 - 6.6e-63 212.5 0.2 9.3e-63 212.0 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40225.1 - 5.5e-29 101.2 0.0 9e-29 100.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC40225.1 - 7e-06 25.6 0.1 0.0001 21.7 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.14 EGC40225.1 - 0.0004 19.8 1.3 0.00042 19.7 0.1 1.6 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.23 EGC40225.1 - 0.00047 20.1 0.0 0.071 13.0 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Choline_kinase PF01633.20 EGC40225.1 - 0.018 14.6 5.9 0.022 14.3 2.2 2.4 2 1 0 2 2 2 0 Choline/ethanolamine kinase Pkinase_fungal PF17667.1 EGC40225.1 - 0.11 11.2 9.0 0.035 12.9 1.8 2.7 2 1 0 2 2 2 0 Fungal protein kinase ArfGap PF01412.18 EGC40225.1 - 9.3 6.4 9.6 0.21 11.7 1.1 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf Zip PF02535.22 EGC40226.1 - 0.28 10.4 0.8 0.37 10.0 0.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter DDE_3 PF13358.6 EGC40227.1 - 1.5e-06 28.1 0.1 3.2e-06 27.0 0.1 1.6 1 1 1 2 2 2 1 DDE superfamily endonuclease LAP2alpha PF11560.8 EGC40227.1 - 0.15 11.5 0.0 0.25 10.8 0.0 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 2 alpha PRF PF06875.11 EGC40229.1 - 0.086 12.3 0.3 0.098 12.1 0.3 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF AAA_23 PF13476.6 EGC40229.1 - 0.57 10.7 6.9 0.68 10.4 6.9 1.1 1 0 0 1 1 1 0 AAA domain MAPEG PF01124.18 EGC40230.1 - 6.2e-30 103.8 0.0 7.3e-30 103.5 0.0 1.0 1 0 0 1 1 1 1 MAPEG family Cys_rich_FGFR PF00839.17 EGC40231.1 - 0.066 13.4 0.2 1.6 8.9 0.0 2.2 2 0 0 2 2 2 0 Cysteine rich repeat AhpC-TSA PF00578.21 EGC40232.1 - 5.3e-41 139.4 0.1 6.1e-41 139.2 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.10 EGC40232.1 - 1.9e-24 86.0 0.0 2.2e-24 85.9 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.6 EGC40232.1 - 9.8e-05 22.6 0.0 0.00018 21.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.6 EGC40232.1 - 0.0065 16.6 0.0 0.008 16.3 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme GSHPx PF00255.19 EGC40232.1 - 0.022 14.3 0.0 0.035 13.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase SCO1-SenC PF02630.14 EGC40232.1 - 0.035 14.0 0.3 0.061 13.2 0.3 1.4 1 1 0 1 1 1 0 SCO1/SenC EGF_2 PF07974.13 EGC40233.1 - 5.8e-11 42.6 69.7 0.00023 21.4 8.3 4.8 4 0 0 4 4 4 4 EGF-like domain TIG PF01833.24 EGC40233.1 - 1e-10 41.5 19.7 9.2e-06 25.7 0.3 5.8 5 1 1 6 6 6 2 IPT/TIG domain Laminin_EGF PF00053.24 EGC40233.1 - 0.00044 20.3 49.9 0.0038 17.3 6.5 4.6 2 1 2 4 4 4 2 Laminin EGF domain LRR_8 PF13855.6 EGC40233.1 - 0.0071 16.1 14.5 0.14 11.9 1.3 4.5 4 1 0 4 4 4 2 Leucine rich repeat SKG6 PF08693.10 EGC40233.1 - 0.01 15.3 5.7 0.019 14.4 5.7 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain LRR_4 PF12799.7 EGC40233.1 - 0.04 14.4 24.2 0.33 11.4 5.0 5.1 3 1 1 5 5 5 0 Leucine Rich repeats (2 copies) OST_IS PF18246.1 EGC40233.1 - 0.12 12.7 0.2 7.3 7.0 0.1 2.8 2 0 0 2 2 2 0 Oligosaccharyltransferase Insert domain LRR_6 PF13516.6 EGC40233.1 - 0.42 10.8 8.3 17 5.8 0.2 4.2 3 0 0 3 3 3 0 Leucine Rich repeat LRR_1 PF00560.33 EGC40233.1 - 0.6 10.9 11.8 6.7 7.7 0.4 5.6 4 0 0 4 4 4 0 Leucine Rich Repeat EGF_Tenascin PF18720.1 EGC40233.1 - 3.4 7.8 28.0 0.86 9.7 1.2 3.7 3 0 0 3 3 3 0 Tenascin EGF domain Kinesin PF00225.23 EGC40234.1 - 9.2e-106 353.5 0.6 9.2e-106 353.5 0.6 4.3 5 0 0 5 5 5 1 Kinesin motor domain Microtub_bd PF16796.5 EGC40234.1 - 5.1e-25 88.2 0.0 5.1e-25 88.2 0.0 3.6 2 1 1 3 3 3 1 Microtubule binding DUF1192 PF06698.11 EGC40234.1 - 0.87 9.7 7.0 0.6 10.2 2.9 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1192) Ribosomal_L19e PF01280.20 EGC40235.1 - 7.2e-61 204.5 7.7 7.2e-61 204.5 7.7 1.7 1 1 1 2 2 2 1 Ribosomal protein L19e EGF_CA PF07645.15 EGC40236.1 - 3.7e-17 62.2 39.2 2.1e-08 34.2 8.4 3.1 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.6 EGC40236.1 - 2.8e-10 40.3 32.2 1.2e-06 28.7 6.6 3.2 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.7 EGC40236.1 - 4.1e-10 39.4 10.6 1.1e-05 25.3 2.0 3.5 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.27 EGC40236.1 - 3.2e-07 30.5 23.7 0.00055 20.2 2.3 4.2 3 2 0 3 3 3 2 EGF-like domain EGF_3 PF12947.7 EGC40236.1 - 3.5e-06 27.1 24.2 0.0093 16.1 2.6 3.8 3 3 0 3 3 3 3 EGF domain hEGF PF12661.7 EGC40236.1 - 0.0002 21.9 12.2 0.0017 19.0 2.9 5.1 4 1 0 4 4 4 2 Human growth factor-like EGF OSK PF17182.4 EGC40236.1 - 0.002 17.4 0.2 0.74 9.0 0.1 2.0 1 1 1 2 2 2 2 OSK domain Plasmod_Pvs28 PF06247.11 EGC40236.1 - 0.019 15.3 13.3 0.053 13.8 4.4 3.8 2 1 2 4 4 4 0 Pvs28 EGF domain EGF_MSP1_1 PF12946.7 EGC40236.1 - 0.056 13.5 1.3 0.056 13.5 1.3 4.6 1 1 2 3 3 3 0 MSP1 EGF domain 1 zf-RING_2 PF13639.6 EGC40237.1 - 1.2e-10 41.5 3.5 2.4e-10 40.6 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_11 PF17123.5 EGC40237.1 - 2.2e-08 33.7 4.3 4.6e-08 32.7 4.3 1.6 1 0 0 1 1 1 1 RING-like zinc finger zf-rbx1 PF12678.7 EGC40237.1 - 5.5e-08 33.0 2.8 2.1e-07 31.1 2.8 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_2 PF13923.6 EGC40237.1 - 4.4e-07 29.6 3.0 9.1e-07 28.6 3.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Zn_ribbon_17 PF17120.5 EGC40237.1 - 4.4e-06 26.2 1.7 7.6e-06 25.5 1.7 1.4 1 0 0 1 1 1 1 Zinc-ribbon, C4HC2 type zf-C3HC4 PF00097.25 EGC40237.1 - 1.3e-05 25.0 4.4 1.3e-05 25.0 4.4 2.1 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC40237.1 - 2.7e-05 24.1 3.2 7.3e-05 22.7 3.2 1.8 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC40237.1 - 4.2e-05 23.4 2.7 9.1e-05 22.3 2.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-ANAPC11 PF12861.7 EGC40237.1 - 0.00081 19.4 0.6 0.0016 18.4 0.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.6 EGC40237.1 - 0.0028 17.5 0.8 0.0057 16.5 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.8 EGC40237.1 - 0.014 15.6 1.4 0.044 14.0 1.4 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.8 EGC40237.1 - 0.025 14.4 1.4 0.068 13.0 1.4 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.6 EGC40237.1 - 0.032 14.4 2.8 0.12 12.5 2.7 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC40237.1 - 0.21 11.5 2.8 0.5 10.3 2.8 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 RINGv PF12906.7 EGC40237.1 - 0.41 10.8 3.4 1.1 9.4 3.4 1.8 1 0 0 1 1 1 0 RING-variant domain MutS_V PF00488.21 EGC40238.1 - 4e-71 239.0 0.1 8.2e-71 237.9 0.1 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.18 EGC40238.1 - 8.6e-32 110.9 0.6 8.6e-32 110.9 0.6 2.8 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.20 EGC40238.1 - 8.6e-30 103.3 0.0 2.7e-29 101.7 0.0 2.0 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.17 EGC40238.1 - 1.1e-13 51.7 1.1 4.9e-13 49.5 0.2 2.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.18 EGC40238.1 - 0.0063 16.8 0.5 0.0063 16.8 0.5 2.5 2 0 0 2 2 2 1 MutS family domain IV DUF4637 PF15470.6 EGC40238.1 - 1.2 8.9 4.6 2.9 7.6 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF5601 PF18151.1 EGC40238.1 - 6.9 7.1 7.4 0.88 9.9 0.3 3.2 3 0 0 3 3 3 0 Domain of unknown function (DUF5601) zf-MYND PF01753.18 EGC40239.1 - 1.3e-08 34.8 14.2 3.1e-08 33.6 14.2 1.7 1 0 0 1 1 1 1 MYND finger SET PF00856.28 EGC40239.1 - 6.6e-08 33.1 0.2 7.1e-05 23.2 0.1 2.7 2 1 0 3 3 3 2 SET domain Septin PF00735.18 EGC40240.1 - 9.2e-10 38.3 0.1 9.2e-10 38.3 0.1 2.4 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EGC40240.1 - 1.5e-06 28.2 0.4 1.3e-05 25.2 0.0 2.7 2 0 0 2 2 2 1 RsgA GTPase MMR_HSR1 PF01926.23 EGC40240.1 - 4.3e-06 26.8 0.8 1.3e-05 25.2 0.1 2.3 2 0 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGC40240.1 - 9e-05 21.9 0.1 0.039 13.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 EGC40240.1 - 0.0044 17.1 16.2 0.012 15.7 0.0 4.7 5 0 0 5 5 5 2 Dynamin family CLP1_P PF16575.5 EGC40240.1 - 0.039 13.8 0.0 0.12 12.1 0.0 1.9 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 EGC40240.1 - 0.047 13.4 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC40240.1 - 0.049 14.0 0.0 0.13 12.6 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGC40240.1 - 0.1 13.1 0.0 0.1 13.1 0.0 2.8 2 1 0 2 2 2 0 ABC transporter RNase_H PF00075.24 EGC40240.1 - 5.9 7.1 6.9 0.6 10.3 0.5 2.7 2 1 1 3 3 3 0 RNase H Septin PF00735.18 EGC40241.1 - 8.7e-09 35.1 0.1 4.2e-08 32.8 0.1 2.2 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGC40241.1 - 7.8e-07 29.2 0.0 4.4e-06 26.7 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.16 EGC40241.1 - 1.6e-06 27.6 0.1 0.039 13.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family RsgA_GTPase PF03193.16 EGC40241.1 - 4.6e-06 26.6 0.3 2.8e-05 24.1 0.0 2.4 2 0 0 2 2 2 1 RsgA GTPase Dynamin_N PF00350.23 EGC40241.1 - 0.0051 16.9 14.6 0.024 14.7 0.0 4.6 4 1 0 4 4 4 2 Dynamin family CLP1_P PF16575.5 EGC40241.1 - 0.022 14.5 0.3 0.12 12.1 0.0 2.4 2 0 0 2 2 2 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_16 PF13191.6 EGC40241.1 - 0.034 14.5 0.0 0.074 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGC40241.1 - 0.046 14.2 0.4 0.22 12.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter AAA_29 PF13555.6 EGC40241.1 - 0.065 13.0 0.0 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1_C PF08438.10 EGC40241.1 - 0.13 12.9 1.4 0.59 10.7 1.4 2.2 1 0 0 1 1 1 0 GTPase of unknown function C-terminal Septin PF00735.18 EGC40242.1 - 0.00032 20.1 0.6 0.00099 18.5 0.1 2.1 2 0 0 2 2 2 1 Septin RsgA_GTPase PF03193.16 EGC40242.1 - 0.0027 17.6 0.1 0.011 15.6 0.1 2.0 1 0 0 1 1 1 1 RsgA GTPase MMR_HSR1 PF01926.23 EGC40242.1 - 0.0034 17.4 0.1 0.011 15.8 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.27 EGC40242.1 - 0.012 16.1 0.1 0.037 14.5 0.1 1.8 1 0 0 1 1 1 0 ABC transporter AAA_29 PF13555.6 EGC40242.1 - 0.015 15.0 0.0 0.033 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain RNase_H PF00075.24 EGC40242.1 - 0.059 13.6 0.8 0.2 11.8 0.3 2.2 2 0 0 2 2 2 0 RNase H AAA_22 PF13401.6 EGC40242.1 - 0.1 12.9 0.0 0.55 10.5 0.0 2.2 2 0 0 2 2 2 0 AAA domain Dynamin_N PF00350.23 EGC40242.1 - 0.13 12.3 0.1 0.13 12.3 0.1 2.6 2 1 0 2 2 2 0 Dynamin family FtsK_SpoIIIE PF01580.18 EGC40242.1 - 0.18 11.1 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Septin PF00735.18 EGC40243.1 - 4.2e-10 39.4 1.2 1.2e-09 37.9 0.1 2.3 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.23 EGC40243.1 - 2.4e-06 27.6 0.1 1.4e-05 25.2 0.1 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC40243.1 - 7.3e-06 26.0 2.0 2e-05 24.5 0.0 2.8 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EGC40243.1 - 9.8e-05 21.8 0.1 0.039 13.3 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 EGC40243.1 - 0.0089 16.1 0.0 0.0089 16.1 0.0 5.0 6 0 0 6 6 6 2 Dynamin family CLP1_P PF16575.5 EGC40243.1 - 0.031 14.1 0.0 0.12 12.1 0.0 2.1 1 0 0 1 1 1 0 mRNA cleavage and polyadenylation factor CLP1 P-loop AAA_29 PF13555.6 EGC40243.1 - 0.048 13.4 0.0 0.14 11.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.6 EGC40243.1 - 0.058 13.8 0.0 0.13 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.27 EGC40243.1 - 0.077 13.5 2.1 0.26 11.8 0.5 2.7 2 1 0 2 2 2 0 ABC transporter FtsK_SpoIIIE PF01580.18 EGC40243.1 - 0.13 11.6 0.0 0.43 9.9 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family Cnd1 PF12717.7 EGC40244.1 - 0.43 10.6 3.9 0.9 9.6 2.5 2.2 1 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Septin PF00735.18 EGC40245.1 - 3.2e-11 43.0 0.1 1.2e-10 41.1 0.1 2.0 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.23 EGC40245.1 - 6.8e-07 29.4 0.0 3.4e-06 27.1 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase RsgA_GTPase PF03193.16 EGC40245.1 - 5.3e-06 26.4 0.5 5.6e-05 23.1 0.0 2.7 3 0 0 3 3 3 1 RsgA GTPase AIG1 PF04548.16 EGC40245.1 - 3.7e-05 23.1 0.0 0.3 10.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.23 EGC40245.1 - 0.00057 20.0 5.4 0.046 13.8 0.0 3.6 4 0 0 4 4 4 2 Dynamin family AAA_16 PF13191.6 EGC40245.1 - 0.014 15.8 0.0 0.029 14.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.22 EGC40245.1 - 0.022 15.1 0.1 0.14 12.6 0.0 2.5 2 0 0 2 2 2 0 RNA helicase AAA_24 PF13479.6 EGC40245.1 - 0.026 14.3 0.0 0.084 12.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA PF00004.29 EGC40245.1 - 0.09 13.2 0.2 0.45 10.9 0.0 2.3 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.6 EGC40245.1 - 0.14 11.9 0.0 0.35 10.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.27 EGC40245.1 - 0.19 12.3 1.9 0.42 11.1 0.2 2.4 2 1 0 2 2 2 0 ABC transporter RRM_3 PF08777.11 EGC40246.1 - 6.4e-29 100.0 12.8 1e-28 99.4 2.1 2.4 2 0 0 2 2 2 2 RNA binding motif La PF05383.17 EGC40246.1 - 4e-24 84.4 0.7 1.1e-23 83.1 0.7 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.22 EGC40246.1 - 9.4e-14 51.0 2.9 2.4e-07 30.4 0.2 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PTS_2-RNA PF01885.16 EGC40246.1 - 0.023 14.8 0.1 0.053 13.6 0.1 1.8 1 1 0 1 1 1 0 RNA 2'-phosphotransferase, Tpt1 / KptA family F-box-like PF12937.7 EGC40247.1 - 5.3e-05 23.0 0.7 0.00016 21.5 0.1 2.0 2 0 0 2 2 2 1 F-box-like DUF3440 PF11922.8 EGC40247.1 - 0.013 15.2 0.8 0.024 14.4 0.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) LRR_6 PF13516.6 EGC40248.1 - 6.5e-12 44.5 42.7 0.015 15.3 1.2 9.5 11 0 0 11 11 11 7 Leucine Rich repeat SpoU_sub_bind PF08032.12 EGC40248.1 - 0.017 15.4 0.1 1.4 9.2 0.0 2.8 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding Ribosomal_L50 PF10501.9 EGC40248.1 - 0.045 13.9 1.3 0.11 12.7 1.3 1.7 1 0 0 1 1 1 0 Ribosomal subunit 39S LRR_2 PF07723.13 EGC40248.1 - 0.07 13.8 4.4 9.8 7.0 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat DUF4347 PF14252.6 EGC40248.1 - 0.23 11.3 1.2 1.7 8.5 0.4 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4347) LRR_4 PF12799.7 EGC40248.1 - 0.27 11.7 57.2 0.26 11.8 9.2 7.9 3 3 5 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.6 EGC40248.1 - 0.79 9.5 55.3 0.31 10.8 2.4 8.3 5 4 3 8 8 8 0 Leucine rich repeat DLH PF01738.18 EGC40249.1 - 1.8e-05 24.4 0.0 2.6e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_1 PF00561.20 EGC40249.1 - 3.6e-05 23.6 0.1 7.6e-05 22.5 0.1 1.6 1 1 1 2 2 2 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.21 EGC40249.1 - 0.0098 15.4 0.0 0.36 10.3 0.0 2.2 1 1 1 2 2 2 1 Prolyl oligopeptidase family Hydrolase_4 PF12146.8 EGC40249.1 - 0.036 13.3 0.0 0.19 11.0 0.0 1.9 1 1 1 2 2 2 0 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC40249.1 - 0.063 13.9 0.0 0.078 13.6 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF410 PF04190.13 EGC40250.1 - 1.5e-68 231.3 0.2 1.8e-68 231.1 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF410) TPR_17 PF13431.6 EGC40250.1 - 0.12 12.8 0.0 2.7 8.6 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat EamA PF00892.20 EGC40251.1 - 6.4e-09 36.1 26.5 7.6e-07 29.4 4.3 3.9 3 1 0 3 3 3 2 EamA-like transporter family Nuc_sug_transp PF04142.15 EGC40251.1 - 1.1e-06 28.1 15.0 4e-06 26.2 15.0 1.9 1 1 0 1 1 1 1 Nucleotide-sugar transporter TPT PF03151.16 EGC40251.1 - 3.9e-06 26.4 20.1 4.9e-06 26.1 15.1 2.5 2 1 0 2 2 2 1 Triose-phosphate Transporter family CRT-like PF08627.10 EGC40251.1 - 6.9e-06 25.2 6.5 6.9e-06 25.2 6.5 2.8 2 1 0 2 2 2 1 CRT-like, chloroquine-resistance transporter-like EmrE PF13536.6 EGC40251.1 - 0.0045 16.6 8.7 0.51 9.9 4.5 3.2 2 1 1 3 3 3 2 Putative multidrug resistance efflux transporter PWI PF01480.17 EGC40251.1 - 0.09 13.1 0.3 8.7 6.7 0.0 3.1 3 0 0 3 3 3 0 PWI domain RIC3 PF15361.6 EGC40251.1 - 0.12 12.8 0.2 0.25 11.7 0.2 1.5 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 DUF4173 PF13777.6 EGC40251.1 - 4.4 6.7 11.1 15 4.9 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4173) Tubulin PF00091.25 EGC40252.1 - 3.4e-67 226.5 0.0 5.6e-67 225.8 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.17 EGC40252.1 - 6.8e-39 132.9 0.0 1.3e-38 132.0 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.6 EGC40252.1 - 0.00042 20.0 0.0 0.0013 18.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain DUF2828 PF11443.8 EGC40254.1 - 2.7e-119 399.1 0.4 2.3e-102 343.2 1.1 2.4 2 1 0 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.14 EGC40254.1 - 0.035 13.5 0.0 0.064 12.6 0.0 1.4 1 0 0 1 1 1 0 VWA domain containing CoxE-like protein Abhydrolase_1 PF00561.20 EGC40255.1 - 2.7e-21 76.4 0.0 6.6e-21 75.1 0.0 1.6 1 1 0 1 1 1 1 alpha/beta hydrolase fold Hydrolase_4 PF12146.8 EGC40255.1 - 1.6e-15 57.1 0.0 2.5e-15 56.4 0.0 1.2 1 0 0 1 1 1 1 Serine aminopeptidase, S33 Abhydrolase_6 PF12697.7 EGC40255.1 - 6.6e-10 40.0 0.0 8.9e-10 39.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.21 EGC40255.1 - 0.00027 20.5 1.1 0.0026 17.3 0.0 2.4 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.18 EGC40255.1 - 0.0021 17.7 0.0 0.47 10.0 0.0 2.4 2 0 0 2 2 2 2 Dienelactone hydrolase family Ndr PF03096.14 EGC40255.1 - 0.0042 15.8 0.0 0.0083 14.9 0.0 1.5 1 1 0 1 1 1 1 Ndr family Abhydrolase_5 PF12695.7 EGC40255.1 - 0.036 13.8 0.0 6 6.6 0.0 2.3 2 0 0 2 2 2 0 Alpha/beta hydrolase family Abhydrolase_4 PF08386.10 EGC40255.1 - 0.058 13.5 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein FSH1 PF03959.13 EGC40255.1 - 0.088 12.5 0.0 0.78 9.4 0.0 2.4 1 1 0 2 2 2 0 Serine hydrolase (FSH1) Abhydrolase_3 PF07859.13 EGC40255.1 - 0.089 12.6 0.0 0.96 9.3 0.0 2.1 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.20 EGC40255.1 - 0.097 12.8 0.0 1.4 9.0 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.20 EGC40255.1 - 0.19 11.4 0.0 0.33 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase DUF3195 PF11424.8 EGC40256.1 - 0.014 15.5 0.5 0.023 14.7 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3195) TERB2 PF15101.6 EGC40257.1 - 3.2e-10 40.4 0.7 3.2e-10 40.4 0.7 2.4 3 1 0 3 3 3 1 Telomere-associated protein TERB2 DUF5401 PF17380.2 EGC40257.1 - 0.67 8.0 21.4 0.015 13.5 14.8 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5401) FNIP PF05725.12 EGC40258.1 - 8.1e-71 234.0 60.4 3.9e-13 49.3 1.3 11.1 5 2 7 13 13 13 13 FNIP Repeat FNIP PF05725.12 EGC40259.1 - 1.7e-66 220.2 60.2 7.4e-10 38.8 5.0 12.3 2 2 10 14 14 14 14 FNIP Repeat Xol-1_GHMP-like PF09109.10 EGC40259.1 - 0.16 11.9 0.3 7.7 6.4 0.0 2.3 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like Peptidase_M24 PF00557.24 EGC40260.1 - 1.6e-58 197.9 0.0 2.1e-58 197.5 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.16 EGC40260.1 - 5.2e-32 110.2 0.0 9.1e-32 109.4 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Aldolase_II PF00596.21 EGC40261.1 - 1.6e-43 148.8 0.1 2e-43 148.5 0.1 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Isochorismatase PF00857.20 EGC40262.1 - 1.3e-33 116.6 0.0 1.7e-33 116.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Herpes_UL4 PF03277.13 EGC40262.1 - 0.04 13.5 0.0 0.063 12.9 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL4 family zf-RING_2 PF13639.6 EGC40263.1 - 8e-11 42.1 13.1 2e-10 40.8 13.1 1.7 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGC40263.1 - 2.6e-07 30.8 7.9 2.1e-06 27.9 8.6 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC40263.1 - 6.6e-07 29.1 14.2 1.7e-06 27.8 14.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC40263.1 - 7e-07 29.0 9.7 1.4e-06 28.0 9.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC40263.1 - 4.1e-06 26.5 12.5 6.5e-06 25.9 11.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC40263.1 - 1.1e-05 25.6 15.8 1.1e-05 25.6 15.8 2.2 1 1 1 2 2 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC40263.1 - 0.00064 19.6 13.1 0.0019 18.2 13.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC40263.1 - 0.0077 16.1 10.0 0.061 13.2 10.3 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.6 EGC40263.1 - 0.02 14.9 9.3 0.054 13.5 9.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-ANAPC11 PF12861.7 EGC40263.1 - 0.02 14.9 2.8 0.049 13.7 2.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_10 PF16685.5 EGC40263.1 - 0.065 13.4 8.9 0.16 12.1 8.9 1.7 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC40263.1 - 0.12 12.6 13.3 0.33 11.1 13.3 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC40263.1 - 0.65 9.8 8.9 1.3 8.8 8.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC40263.1 - 3.9 7.2 9.5 7.4 6.3 9.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Baculo_11_kDa PF06143.11 EGC40264.1 - 0.032 13.8 0.1 0.12 12.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ctr PF04145.15 EGC40264.1 - 0.54 10.9 4.4 1.5 9.4 4.4 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DUF4083 PF13314.6 EGC40264.1 - 1.7 8.6 6.9 2.1 8.3 1.5 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) zf-RING_2 PF13639.6 EGC40266.1 - 7.4e-11 42.2 13.1 1.6e-10 41.1 13.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.7 EGC40266.1 - 4.6e-07 30.0 8.4 1.4e-06 28.4 8.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4 PF00097.25 EGC40266.1 - 5.5e-07 29.4 14.2 1.4e-06 28.1 14.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC40266.1 - 7.1e-07 29.0 9.9 1.3e-06 28.1 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC40266.1 - 5.3e-06 26.2 11.4 5.3e-06 26.2 11.4 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.13 EGC40266.1 - 0.0011 19.0 49.0 0.0039 17.3 49.1 1.6 1 1 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.6 EGC40266.1 - 0.0015 18.4 13.1 0.0015 18.4 13.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Prok-RING_4 PF14447.6 EGC40266.1 - 0.0069 16.2 10.2 0.062 13.2 10.6 2.2 1 1 1 2 2 2 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC40266.1 - 0.016 15.3 2.7 0.037 14.1 2.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.6 EGC40266.1 - 0.017 15.1 9.3 0.044 13.8 9.3 1.8 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_10 PF16685.5 EGC40266.1 - 0.021 15.0 7.5 0.05 13.7 7.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 zf-C3HC4_4 PF15227.6 EGC40266.1 - 0.099 12.8 13.3 0.27 11.4 13.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_11 PF17123.5 EGC40266.1 - 0.56 10.0 8.9 1.1 9.1 8.9 1.5 1 0 0 1 1 1 0 RING-like zinc finger zf-RING_6 PF14835.6 EGC40266.1 - 1.4 8.9 5.2 2.9 7.8 5.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Zn_ribbon_17 PF17120.5 EGC40266.1 - 3.1 7.5 9.5 5.9 6.6 9.5 1.4 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type Asp-B-Hydro_N PF05279.11 EGC40266.1 - 7.8 6.5 34.9 0.72 9.9 25.8 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF4692 PF15763.5 EGC40267.1 - 0.55 10.7 4.4 1.4 9.4 4.4 1.6 1 0 0 1 1 1 0 Regulator of human erythroid cell expansion (RHEX) RPA43_OB PF17875.1 EGC40267.1 - 5.4 7.7 10.2 0.5 11.0 3.3 2.3 2 0 0 2 2 2 0 RPA43 OB domain in RNA Pol I COG5 PF10392.9 EGC40268.1 - 1.8 8.7 9.3 0.22 11.7 1.4 3.4 3 1 1 4 4 4 0 Golgi transport complex subunit 5 zf-B_box PF00643.24 EGC40270.1 - 5.9e-08 32.7 2.3 1.2e-07 31.8 2.3 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40270.1 - 0.02 15.1 2.0 0.06 13.5 1.5 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) ThiD2 PF17792.1 EGC40270.1 - 0.052 14.0 1.9 0.083 13.4 1.1 1.8 1 1 1 2 2 2 0 ThiD2 family DUF2757 PF10955.8 EGC40270.1 - 2.3 8.5 8.3 0.31 11.3 1.2 3.1 2 2 0 2 2 2 0 Protein of unknown function (DUF2757) MMS1_N PF10433.9 EGC40273.1 - 1.4e-159 531.8 0.3 2.6e-159 531.0 0.3 1.4 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.15 EGC40273.1 - 4.6e-101 338.3 0.0 8.6e-100 334.2 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region CNH PF00780.22 EGC40273.1 - 0.054 13.1 0.0 0.78 9.3 0.0 2.5 2 0 0 2 2 2 0 CNH domain EF-1_beta_acid PF10587.9 EGC40273.1 - 0.41 11.1 2.1 1 9.9 2.1 1.7 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region PHTB1_N PF14727.6 EGC40273.1 - 1.4 8.2 3.4 55 2.9 0.0 3.4 3 1 0 3 3 3 0 PTHB1 N-terminus zf-C2H2_12 PF18658.1 EGC40274.1 - 4.3e-05 23.0 0.0 0.35 10.5 0.0 2.6 2 0 0 2 2 2 2 Zinc-finger C2H2-type zf_UBZ PF18439.1 EGC40274.1 - 0.45 10.1 3.6 1.3 8.7 0.3 2.6 2 0 0 2 2 2 0 Ubiquitin-Binding Zinc Finger DUF4193 PF13834.6 EGC40274.1 - 6 7.4 6.8 13 6.3 0.1 3.0 2 2 1 3 3 3 0 Domain of unknown function (DUF4193) Ank_2 PF12796.7 EGC40275.1 - 7.9e-19 68.0 1.6 8.2e-13 48.8 0.2 3.9 2 1 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC40275.1 - 2.7e-18 66.1 3.1 1e-10 41.9 0.3 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC40275.1 - 1.8e-13 49.3 2.3 0.00049 20.3 0.0 7.3 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGC40275.1 - 6.6e-13 48.6 0.9 3.1e-09 36.9 0.2 4.8 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank PF00023.30 EGC40275.1 - 8e-05 22.9 7.5 0.81 10.2 0.0 5.3 5 1 0 5 5 5 2 Ankyrin repeat Ank_2 PF12796.7 EGC40276.1 - 1.2e-25 89.9 8.0 3.3e-12 46.8 0.3 4.4 2 1 2 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.6 EGC40276.1 - 4.6e-16 58.9 1.0 1.6e-07 31.8 0.1 5.8 3 1 3 6 6 6 4 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC40276.1 - 2.3e-13 49.0 2.0 0.43 11.3 0.0 7.6 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.6 EGC40276.1 - 2.8e-11 43.4 0.0 0.004 17.4 0.0 5.9 4 1 2 6 6 6 3 Ankyrin repeats (many copies) Ank PF00023.30 EGC40276.1 - 5.2e-09 36.1 0.7 0.47 11.0 0.0 6.1 7 0 0 7 7 7 3 Ankyrin repeat DUF3645 PF12359.8 EGC40279.1 - 0.0025 17.2 0.1 2.3 7.7 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3645) OTU PF02338.19 EGC40280.1 - 4e-12 46.7 0.0 4e-12 46.7 0.0 3.3 2 1 1 3 3 3 1 OTU-like cysteine protease TFIIA PF03153.13 EGC40280.1 - 0.17 11.9 41.9 0.23 11.4 41.9 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Presenilin PF01080.17 EGC40280.1 - 0.26 10.0 11.4 0.34 9.6 11.4 1.3 1 0 0 1 1 1 0 Presenilin DUF4529 PF15032.6 EGC40280.1 - 1.6 7.7 11.2 2.1 7.3 11.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4529) Band_3_cyto PF07565.13 EGC40280.1 - 1.7 8.4 15.8 2.7 7.7 15.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Vac7 PF12751.7 EGC40280.1 - 6.1 6.2 9.3 8.2 5.8 9.3 1.1 1 0 0 1 1 1 0 Vacuolar segregation subunit 7 PAT1 PF09770.9 EGC40280.1 - 6.5 4.9 37.4 8.1 4.6 37.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dimer_Tnp_hAT PF05699.14 EGC40281.1 - 6.8e-15 54.6 0.1 1.5e-14 53.5 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4420 PF14390.6 EGC40281.1 - 0.0022 17.3 0.5 0.0035 16.6 0.5 1.3 1 0 0 1 1 1 1 Putative PD-(D/E)XK family member, (DUF4420) Ras PF00071.22 EGC40283.1 - 9.4e-34 116.3 1.6 1.2e-33 116.0 1.6 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC40283.1 - 8.2e-19 68.0 0.7 1.4e-18 67.2 0.7 1.4 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC40283.1 - 1.2e-09 37.9 1.0 1.9e-09 37.3 1.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.9 EGC40283.1 - 0.00079 19.2 0.2 1 9.1 0.1 2.7 1 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation KR PF08659.10 EGC40283.1 - 0.18 11.7 0.0 0.26 11.2 0.0 1.2 1 0 0 1 1 1 0 KR domain MMR_HSR1 PF01926.23 EGC40283.1 - 0.19 11.8 1.1 0.27 11.3 0.1 1.8 2 2 0 2 2 2 0 50S ribosome-binding GTPase PTR2 PF00854.21 EGC40284.1 - 2.2e-91 306.6 12.8 3e-91 306.2 12.8 1.1 1 0 0 1 1 1 1 POT family DUF2615 PF11027.8 EGC40284.1 - 0.021 15.0 1.0 0.043 13.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2615) DUF4231 PF14015.6 EGC40284.1 - 2.9 8.4 6.9 19 5.8 0.4 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) Peptidase_M66 PF10462.9 EGC40285.1 - 2.1e-114 381.6 3.0 2.8e-114 381.2 3.0 1.2 1 0 0 1 1 1 1 Peptidase M66 ACD PF16671.5 EGC40285.1 - 0.025 12.9 0.2 0.056 11.8 0.2 1.5 1 0 0 1 1 1 0 Actin cross-linking domain Reprolysin_3 PF13582.6 EGC40285.1 - 0.052 14.1 0.2 0.11 13.0 0.2 1.6 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_4 PF13583.6 EGC40285.1 - 0.073 12.7 0.1 0.15 11.7 0.1 1.5 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like TagA PF12561.8 EGC40285.1 - 0.14 12.6 0.6 0.58 10.6 0.0 2.4 3 0 0 3 3 3 0 ToxR activated gene A lipoprotein domain Metallopep PF12044.8 EGC40285.1 - 0.17 10.4 0.6 0.31 9.6 0.6 1.3 1 0 0 1 1 1 0 Putative peptidase family ROK PF00480.20 EGC40286.1 - 2.1e-55 188.3 0.0 2.5e-55 188.1 0.0 1.1 1 0 0 1 1 1 1 ROK family RNA_pol_Rpb5_C PF01191.19 EGC40286.1 - 0.16 11.8 0.0 0.44 10.4 0.0 1.7 1 0 0 1 1 1 0 RNA polymerase Rpb5, C-terminal domain Glucokinase PF02685.16 EGC40286.1 - 0.62 9.0 3.3 0.37 9.8 0.1 2.1 3 0 0 3 3 3 0 Glucokinase Surp PF01805.20 EGC40287.1 - 4.7e-14 52.1 4.1 8e-14 51.4 2.7 2.1 2 0 0 2 2 2 1 Surp module RRM_1 PF00076.22 EGC40287.1 - 5e-14 51.9 0.0 1.4e-13 50.5 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.13 EGC40287.1 - 8.3e-07 29.8 0.6 5.1e-06 27.2 0.6 2.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_5 PF13893.6 EGC40287.1 - 0.0006 19.4 0.0 0.0024 17.5 0.0 2.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_occluded PF16842.5 EGC40287.1 - 0.081 12.8 0.3 0.53 10.2 0.0 2.5 3 0 0 3 3 3 0 Occluded RNA-recognition motif Ribosomal_S26e PF01283.19 EGC40288.1 - 1.2e-48 164.0 8.7 1.4e-48 163.8 8.7 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Methyltr_RsmB-F PF01189.17 EGC40289.1 - 3.9e-73 245.4 0.0 8.5e-73 244.3 0.0 1.6 1 0 0 1 1 1 1 16S rRNA methyltransferase RsmB/F Methyltr_RsmF_N PF17125.5 EGC40289.1 - 2.9e-10 40.5 0.0 1.1e-09 38.6 0.0 2.0 1 0 0 1 1 1 1 N-terminal domain of 16S rRNA methyltransferase RsmF Met_10 PF02475.16 EGC40289.1 - 1.5e-05 24.8 0.1 2.9e-05 23.9 0.1 1.4 1 0 0 1 1 1 1 Met-10+ like-protein PCMT PF01135.19 EGC40289.1 - 0.00015 21.6 0.0 0.00031 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) FtsJ PF01728.19 EGC40289.1 - 0.00047 20.3 0.1 0.00096 19.3 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.6 EGC40289.1 - 0.0039 17.9 0.0 0.0086 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain UPF0688 PF15772.5 EGC40290.1 - 0.0026 18.1 1.7 0.0032 17.8 0.0 1.8 2 0 0 2 2 2 1 UPF0688 family LSM PF01423.22 EGC40290.1 - 0.032 13.9 0.2 0.19 11.4 0.0 2.4 2 0 0 2 2 2 0 LSM domain HNH_2 PF13391.6 EGC40291.1 - 6.7e-06 26.1 0.5 4.2e-05 23.6 0.5 2.1 1 1 0 1 1 1 1 HNH endonuclease DDE_Tnp_4 PF13359.6 EGC40292.1 - 1.4e-05 24.8 0.7 1.6e-05 24.7 0.7 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC40292.1 - 0.033 13.8 0.2 0.041 13.5 0.2 1.2 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_4 PF13359.6 EGC40293.1 - 3.4e-12 46.3 0.4 3.9e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.21 EGC40293.1 - 0.011 15.4 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain HTH_Tnp_4 PF13613.6 EGC40293.1 - 0.011 15.4 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DUF5501 PF17605.2 EGC40293.1 - 0.045 14.2 0.2 0.082 13.3 0.0 1.5 2 0 0 2 2 2 0 Family of unknown function (DUF5501) HTH_psq PF05225.16 EGC40293.1 - 0.19 11.5 0.0 0.35 10.6 0.0 1.4 1 0 0 1 1 1 0 helix-turn-helix, Psq domain Guanylate_cyc_2 PF09778.9 EGC40294.1 - 7.7e-50 169.2 5.6 5.1e-33 114.2 1.2 2.1 2 0 0 2 2 2 2 Guanylylate cyclase Peptidase_C39_2 PF13529.6 EGC40294.1 - 4.1e-06 27.4 11.8 0.00045 20.8 4.9 3.1 1 1 1 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGC40294.1 - 2.5e-05 24.3 0.2 0.044 13.8 0.0 2.5 3 0 0 3 3 3 2 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 EGC40294.1 - 0.0012 18.6 0.2 0.15 11.8 0.0 2.7 2 0 0 2 2 2 2 Peptidase C39 family Prefoldin_2 PF01920.20 EGC40295.1 - 4.5e-15 55.5 9.4 6.4e-15 55.0 9.4 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.17 EGC40295.1 - 0.00045 20.1 0.8 0.00045 20.1 0.8 2.1 2 0 0 2 2 2 1 Prefoldin subunit Snf7 PF03357.21 EGC40295.1 - 0.036 13.7 8.0 0.045 13.3 0.3 2.1 2 0 0 2 2 2 0 Snf7 MbeB_N PF04837.12 EGC40295.1 - 0.072 13.4 0.2 0.072 13.4 0.2 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region RNA_polI_A14 PF08203.11 EGC40295.1 - 0.23 12.2 0.3 0.23 12.2 0.3 1.8 2 1 0 2 2 2 0 Yeast RNA polymerase I subunit RPA14 Spore_III_AB PF09548.10 EGC40295.1 - 0.23 11.5 3.7 0.34 11.0 3.7 1.3 1 0 0 1 1 1 0 Stage III sporulation protein AB (spore_III_AB) DUF4337 PF14235.6 EGC40295.1 - 6.7 6.8 6.2 15 5.7 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4337) Pkinase_Tyr PF07714.17 EGC40296.1 - 4.9e-66 222.6 0.0 6.4e-66 222.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.25 EGC40296.1 - 6.3e-59 199.5 0.0 9.3e-59 198.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.24 EGC40296.1 - 8.6e-11 41.8 6.9 8.6e-11 41.8 6.9 2.2 2 0 0 2 2 2 1 IPT/TIG domain TIG_plexin PF17960.1 EGC40296.1 - 0.021 14.8 0.1 0.064 13.3 0.1 1.8 1 0 0 1 1 1 0 TIG domain APH PF01636.23 EGC40296.1 - 0.041 13.8 0.3 0.081 12.8 0.3 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family Slu7 PF11708.8 EGC40297.1 - 5.6e-90 301.8 14.9 5.6e-90 301.8 14.9 2.4 2 0 0 2 2 2 1 Pre-mRNA splicing Prp18-interacting factor zf-CCHC_4 PF14392.6 EGC40297.1 - 0.36 10.6 2.5 0.85 9.4 2.5 1.6 1 0 0 1 1 1 0 Zinc knuckle DUF3682 PF12446.8 EGC40297.1 - 9.9 6.7 9.9 41 4.7 9.9 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3682) Cob_adeno_trans PF01923.18 EGC40298.1 - 7.2e-50 169.3 0.0 8.3e-50 169.1 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase CLU PF13236.6 EGC40299.1 - 3.2e-50 171.0 0.0 8e-50 169.7 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria Ras PF00071.22 EGC40299.1 - 2.2e-21 76.2 0.1 6.2e-16 58.4 0.0 3.1 2 1 1 3 3 3 2 Ras family Roc PF08477.13 EGC40299.1 - 1.7e-06 28.2 4.0 0.0079 16.4 0.0 3.5 2 1 1 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase TPR_2 PF07719.17 EGC40299.1 - 0.0019 18.1 1.0 0.11 12.6 0.2 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.6 EGC40299.1 - 0.078 13.3 0.0 0.5 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain TPR_1 PF00515.28 EGC40299.1 - 0.11 12.3 0.9 0.65 9.9 0.2 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.6 EGC40299.1 - 0.12 12.7 0.1 0.28 11.5 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat AAA_16 PF13191.6 EGC40299.1 - 0.12 12.7 0.0 0.58 10.5 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain TPR_8 PF13181.6 EGC40299.1 - 0.14 12.5 0.2 0.92 9.9 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.26 EGC40301.1 - 2.5e-57 193.4 0.2 4.1e-57 192.8 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.9 EGC40301.1 - 2.1e-14 52.9 0.1 3.7e-14 52.1 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_C12 PF01088.21 EGC40302.1 - 5.1e-60 202.8 0.1 6.8e-60 202.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 HipN PF18253.1 EGC40302.1 - 0.035 13.8 0.1 2 8.1 0.0 3.0 3 0 0 3 3 3 0 Hsp70-interacting protein N N-terminal domain Baculo_11_kDa PF06143.11 EGC40303.1 - 0.016 14.8 0.1 0.064 12.8 0.1 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family Ctr PF04145.15 EGC40303.1 - 0.89 10.2 5.2 2.8 8.6 5.2 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DUF2935 PF11155.8 EGC40303.1 - 8.2 6.8 12.1 41 4.5 7.8 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF2935) Methyltransf_10 PF05971.12 EGC40304.1 - 4.9e-05 22.8 0.0 6.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 RNA methyltransferase zf-RING_2 PF13639.6 EGC40305.1 - 5.9e-10 39.3 10.0 9.8e-10 38.6 10.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.6 EGC40305.1 - 7.1e-09 35.4 7.8 1.2e-08 34.7 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC40305.1 - 1.1e-08 34.8 8.5 1.8e-08 34.1 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC40305.1 - 1.3e-07 31.4 11.1 2.4e-07 30.5 11.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC40305.1 - 1.8e-06 28.1 5.3 4.9e-06 26.7 5.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC40305.1 - 2.2e-05 24.4 4.7 4.2e-05 23.5 4.7 1.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC40305.1 - 9.2e-05 22.3 9.9 0.00019 21.4 9.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.6 EGC40305.1 - 0.00099 18.8 10.0 0.0018 18.0 10.0 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_11 PF17123.5 EGC40305.1 - 0.0015 18.3 6.8 0.003 17.3 6.8 1.6 1 0 0 1 1 1 1 RING-like zinc finger Prok-RING_4 PF14447.6 EGC40305.1 - 0.0023 17.7 6.0 0.0051 16.7 6.0 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-ANAPC11 PF12861.7 EGC40305.1 - 0.0039 17.2 1.4 0.0092 16.0 1.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC40305.1 - 0.044 13.9 10.3 0.12 12.6 10.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Hamartin PF04388.12 EGC40305.1 - 0.063 11.9 33.6 0.095 11.4 33.6 1.2 1 0 0 1 1 1 0 Hamartin protein DZR PF12773.7 EGC40305.1 - 0.23 11.5 4.7 0.65 10.1 4.7 1.8 1 0 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.6 EGC40305.1 - 0.36 10.7 2.8 0.77 9.7 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.11 EGC40305.1 - 0.78 9.9 5.9 1.6 8.9 5.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.21 EGC40305.1 - 5.7 7.3 10.1 45 4.4 0.4 2.6 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain AAA PF00004.29 EGC40307.1 - 2.6e-90 299.7 0.0 1.1e-47 161.8 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_lid_3 PF17862.1 EGC40307.1 - 2.7e-20 71.9 0.0 9.7e-09 34.9 0.0 2.7 2 0 0 2 2 2 2 AAA+ lid domain AAA_2 PF07724.14 EGC40307.1 - 1.2e-15 58.1 0.0 2e-07 31.3 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) Nucleolin_bd PF16725.5 EGC40307.1 - 2e-14 53.0 0.0 5.2e-14 51.7 0.0 1.7 1 0 0 1 1 1 1 Nucleolin binding domain AAA_16 PF13191.6 EGC40307.1 - 1.3e-13 51.7 0.7 0.0012 19.3 0.0 4.7 3 2 1 4 4 3 2 AAA ATPase domain RuvB_N PF05496.12 EGC40307.1 - 3.6e-13 49.6 0.0 2.3e-05 24.2 0.0 3.2 3 0 0 3 3 3 2 Holliday junction DNA helicase RuvB P-loop domain AAA_5 PF07728.14 EGC40307.1 - 1.8e-11 44.2 0.0 0.00042 20.3 0.0 3.5 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.6 EGC40307.1 - 4.4e-10 40.0 1.8 0.03 14.6 0.1 5.2 3 2 1 4 4 3 2 AAA domain TIP49 PF06068.13 EGC40307.1 - 3.5e-09 36.3 0.1 0.00042 19.6 0.1 2.5 2 0 0 2 2 2 2 TIP49 P-loop domain AAA_14 PF13173.6 EGC40307.1 - 5.7e-09 36.1 0.0 0.0037 17.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.22 EGC40307.1 - 8.4e-09 35.8 0.0 0.0051 17.2 0.0 3.9 3 0 0 3 3 2 2 RNA helicase ABC_tran PF00005.27 EGC40307.1 - 5.1e-08 33.5 5.6 0.0066 17.0 0.1 3.8 3 1 0 3 3 3 2 ABC transporter AAA_33 PF13671.6 EGC40307.1 - 1.8e-07 31.4 2.9 0.0051 17.0 0.0 3.3 4 0 0 4 4 2 2 AAA domain Mg_chelatase PF01078.21 EGC40307.1 - 3.2e-07 29.9 0.3 0.013 14.9 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI NACHT PF05729.12 EGC40307.1 - 3.3e-07 30.4 0.4 0.053 13.4 0.2 3.8 2 2 1 4 4 4 2 NACHT domain IstB_IS21 PF01695.17 EGC40307.1 - 7e-07 29.1 0.0 0.02 14.6 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein TsaE PF02367.17 EGC40307.1 - 2.8e-06 27.3 0.0 0.09 12.8 0.0 2.4 2 0 0 2 2 2 2 Threonylcarbamoyl adenosine biosynthesis protein TsaE Zeta_toxin PF06414.12 EGC40307.1 - 9.5e-06 25.0 0.1 0.01 15.1 0.0 2.8 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.6 EGC40307.1 - 1e-05 25.8 0.0 0.18 12.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.10 EGC40307.1 - 1.2e-05 25.2 0.8 0.16 12.0 0.1 2.7 2 0 0 2 2 2 2 Vps4 C terminal oligomerisation domain Sigma54_activat PF00158.26 EGC40307.1 - 1.5e-05 24.8 0.0 0.11 12.2 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain ATPase_2 PF01637.18 EGC40307.1 - 2.9e-05 24.1 2.7 0.2 11.6 0.0 4.0 3 2 2 5 5 5 2 ATPase domain predominantly from Archaea Rad17 PF03215.15 EGC40307.1 - 3.6e-05 23.8 0.0 0.47 10.4 0.0 3.0 2 0 0 2 2 2 2 Rad17 P-loop domain AAA_24 PF13479.6 EGC40307.1 - 4.6e-05 23.2 0.2 0.44 10.3 0.0 3.3 3 1 0 3 3 2 2 AAA domain Viral_helicase1 PF01443.18 EGC40307.1 - 7.1e-05 22.7 0.0 0.13 12.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_7 PF12775.7 EGC40307.1 - 0.00016 21.3 0.0 0.76 9.3 0.0 2.7 2 1 0 2 2 2 2 P-loop containing dynein motor region ATPase PF06745.13 EGC40307.1 - 0.00022 20.6 0.4 1.7 7.9 0.0 3.5 2 1 0 3 3 3 1 KaiC AAA_3 PF07726.11 EGC40307.1 - 0.0009 19.1 0.0 0.61 9.9 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NB-ARC PF00931.22 EGC40307.1 - 0.00093 18.5 4.6 0.32 10.1 0.0 3.3 5 0 0 5 5 3 2 NB-ARC domain PhoH PF02562.16 EGC40307.1 - 0.0011 18.5 0.2 1.2 8.5 0.0 2.7 2 0 0 2 2 2 2 PhoH-like protein AAA_25 PF13481.6 EGC40307.1 - 0.0012 18.4 0.8 6.3 6.3 0.0 3.9 4 0 0 4 4 4 0 AAA domain AAA_17 PF13207.6 EGC40307.1 - 0.0012 19.2 0.1 0.8 10.1 0.0 3.2 3 0 0 3 3 2 1 AAA domain AAA_18 PF13238.6 EGC40307.1 - 0.0017 18.9 12.0 0.18 12.3 0.0 4.8 4 2 0 4 4 4 2 AAA domain DUF815 PF05673.13 EGC40307.1 - 0.0019 17.4 0.0 0.57 9.3 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Bac_DnaA PF00308.18 EGC40307.1 - 0.0022 17.8 0.0 0.84 9.4 0.0 2.7 2 0 0 2 2 2 1 Bacterial dnaA protein PduV-EutP PF10662.9 EGC40307.1 - 0.0038 17.0 0.0 1.4 8.7 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation NTPase_1 PF03266.15 EGC40307.1 - 0.0049 16.8 0.6 1.7 8.6 0.0 3.6 3 1 0 4 4 4 1 NTPase Cytidylate_kin PF02224.18 EGC40307.1 - 0.0081 15.9 0.2 2.5 7.8 0.1 2.8 2 0 0 2 2 2 1 Cytidylate kinase Cytidylate_kin2 PF13189.6 EGC40307.1 - 0.029 14.5 0.0 8.1 6.5 0.0 2.6 2 0 0 2 2 2 0 Cytidylate kinase-like family Sigma54_activ_2 PF14532.6 EGC40307.1 - 0.038 14.1 0.0 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Sigma-54 interaction domain SKI PF01202.22 EGC40307.1 - 0.058 13.5 2.2 5.7 7.0 0.0 3.0 3 0 0 3 3 2 0 Shikimate kinase CPT PF07931.12 EGC40307.1 - 0.11 12.3 0.0 4.1 7.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.16 EGC40307.1 - 0.15 11.0 0.0 3.7 6.3 0.0 2.4 2 0 0 2 2 2 0 AFG1-like ATPase Ndc1_Nup PF09531.10 EGC40307.1 - 0.31 9.7 1.7 0.42 9.2 1.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FNIP PF05725.12 EGC40308.1 - 3e-67 222.6 59.8 4.5e-13 49.1 3.6 8.0 3 2 5 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.13 EGC40308.1 - 0.00079 19.8 0.0 20 5.6 0.0 4.4 3 1 2 5 5 5 2 Phage minor tail protein LRR_5 PF13306.6 EGC40308.1 - 0.036 14.0 12.3 0.66 9.9 7.5 3.4 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Pkinase PF00069.25 EGC40309.1 - 2.2e-50 171.5 2.4 2.4e-50 171.3 2.4 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40309.1 - 3.9e-32 111.5 0.3 4.7e-32 111.3 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC40309.1 - 1.3e-06 27.5 0.7 1.9e-06 27.0 0.2 1.4 1 1 0 1 1 1 1 Fungal protein kinase Kinase-like PF14531.6 EGC40309.1 - 0.0008 18.8 0.0 0.001 18.4 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Haspin_kinase PF12330.8 EGC40309.1 - 0.0018 17.3 0.3 0.0018 17.3 0.3 1.5 2 0 0 2 2 2 1 Haspin like kinase domain Seadorna_VP7 PF07387.11 EGC40309.1 - 0.0043 16.2 0.1 0.0079 15.3 0.1 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 APH PF01636.23 EGC40309.1 - 0.0049 16.8 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family OTU PF02338.19 EGC40310.1 - 3e-13 50.4 0.1 5.2e-13 49.6 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease OTU PF02338.19 EGC40311.1 - 8.1e-15 55.4 0.1 1.4e-14 54.7 0.1 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease FNIP PF05725.12 EGC40314.1 - 5.9e-93 304.8 67.2 4.4e-12 46.0 0.3 12.7 6 4 6 15 15 15 13 FNIP Repeat LRR_5 PF13306.6 EGC40314.1 - 4.2 7.4 15.5 17 5.4 1.2 4.5 2 2 2 4 4 4 0 BspA type Leucine rich repeat region (6 copies) Ins134_P3_kin PF05770.11 EGC40315.1 - 2.6e-44 151.2 1.0 3.4e-44 150.8 0.3 1.5 2 0 0 2 2 2 1 Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain Ins134_P3_kin_N PF17927.1 EGC40315.1 - 4.7e-07 30.1 3.6 8e-07 29.4 0.1 2.8 3 1 1 4 4 4 1 Inositol 1,3,4-trisphosphate 5/6-kinase pre-ATP-grasp domain ATP-grasp_3 PF02655.14 EGC40315.1 - 3.4e-05 23.9 0.1 9.6e-05 22.5 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain FNIP PF05725.12 EGC40318.1 - 5.3e-73 241.0 47.3 2.3e-14 53.3 3.1 6.1 2 1 6 8 8 8 8 FNIP Repeat LRR_1 PF00560.33 EGC40318.1 - 1.7 9.5 8.4 4.4 8.2 1.2 4.1 3 2 0 3 3 3 0 Leucine Rich Repeat NUC153 PF08159.12 EGC40320.1 - 1.4e-10 40.8 0.1 1.5e-08 34.3 0.1 3.0 2 0 0 2 2 2 2 NUC153 domain DUF2722 PF10846.8 EGC40320.1 - 0.0067 15.4 16.2 0.0067 15.4 16.2 4.6 2 1 0 3 3 3 1 Protein of unknown function (DUF2722) HA2 PF04408.23 EGC40321.1 - 1.4e-18 67.1 0.0 3.2e-18 66.0 0.0 1.7 1 1 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.16 EGC40321.1 - 1.6e-18 66.9 0.2 3.9e-18 65.6 0.1 1.8 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.31 EGC40321.1 - 2.7e-11 43.8 0.0 7e-11 42.5 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1848 PF08902.11 EGC40321.1 - 0.016 15.0 0.4 0.03 14.1 0.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Ubiq_cyt_C_chap PF03981.12 EGC40322.1 - 5.2e-30 104.4 0.1 7.3e-30 103.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF489 PF04356.12 EGC40323.1 - 0.02 14.9 2.6 0.091 12.8 2.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF489) FadA PF09403.10 EGC40323.1 - 0.078 13.5 4.9 1.1 9.8 0.3 2.6 1 1 1 2 2 2 0 Adhesion protein FadA Colicin PF01024.19 EGC40323.1 - 0.14 12.0 3.4 0.12 12.3 0.9 1.8 1 1 1 2 2 2 0 Colicin pore forming domain DUF641 PF04859.12 EGC40323.1 - 0.15 12.4 2.2 0.16 12.3 1.1 1.6 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Transposase_24 PF03004.14 EGC40323.1 - 0.4 10.8 3.6 0.3 11.2 0.9 2.1 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) TMF_DNA_bd PF12329.8 EGC40323.1 - 3 7.9 10.2 0.45 10.5 6.0 1.9 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding FNIP PF05725.12 EGC40325.1 - 0.00045 20.3 12.2 0.021 15.0 0.5 4.1 2 1 1 3 3 3 2 FNIP Repeat DUF4033 PF13225.6 EGC40325.1 - 0.046 13.7 0.2 0.14 12.1 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) FNIP PF05725.12 EGC40326.1 - 7.7e-45 150.8 29.9 1.6e-13 50.5 0.7 5.7 4 2 2 7 7 7 5 FNIP Repeat rpo30_N PF12410.8 EGC40326.1 - 0.055 13.4 0.1 0.085 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit VPS9 PF02204.18 EGC40327.1 - 4.7e-11 42.8 0.5 4.7e-11 42.8 0.5 2.5 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.7 EGC40327.1 - 1.1e-08 35.5 4.6 0.0079 16.8 0.0 4.7 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank_3 PF13606.6 EGC40327.1 - 6.2e-06 26.2 0.2 30 5.7 0.0 6.1 5 0 0 5 5 5 1 Ankyrin repeat Ank_4 PF13637.6 EGC40327.1 - 7.9e-06 26.3 0.1 4 8.1 0.0 5.5 3 1 2 5 5 5 2 Ankyrin repeats (many copies) SpaA PF17802.1 EGC40327.1 - 0.016 15.5 0.1 0.043 14.1 0.1 1.7 1 0 0 1 1 1 0 Prealbumin-like fold domain MRNIP PF15749.5 EGC40330.1 - 5e-21 75.5 20.6 5e-21 75.5 20.6 4.9 3 2 0 3 3 3 1 MRN-interacting protein Tfb4 PF03850.14 EGC40332.1 - 1.5e-86 290.3 11.6 1.8e-86 290.1 11.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 PepSY_TM_like_2 PF16357.5 EGC40332.1 - 0.1 12.6 0.7 0.16 11.9 0.7 1.3 1 0 0 1 1 1 0 Putative PepSY_TM-like PP2C PF00481.21 EGC40334.1 - 3.2e-52 177.7 0.0 7.6e-52 176.5 0.0 1.7 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_8 PF13855.6 EGC40334.1 - 1.3e-36 124.1 58.6 2.9e-09 36.5 1.4 9.4 6 2 1 9 9 9 7 Leucine rich repeat LRR_4 PF12799.7 EGC40334.1 - 9.6e-33 111.7 70.3 1.2e-05 25.6 1.4 12.1 8 4 4 12 12 12 10 Leucine Rich repeats (2 copies) LRR_6 PF13516.6 EGC40334.1 - 2.5e-05 24.0 39.2 0.24 11.6 0.3 11.4 12 0 0 12 12 12 3 Leucine Rich repeat LRR_9 PF14580.6 EGC40334.1 - 3.2e-05 23.5 16.9 0.43 10.1 0.1 5.5 3 1 2 5 5 5 3 Leucine-rich repeat LRR_1 PF00560.33 EGC40334.1 - 0.00022 21.3 53.5 1.4 9.8 0.6 14.2 12 3 1 13 13 13 2 Leucine Rich Repeat PP2C_2 PF13672.6 EGC40334.1 - 0.00029 20.5 0.0 0.00056 19.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C CTP_transf_1 PF01148.20 EGC40335.1 - 6.7e-63 212.9 21.6 1.1e-62 212.2 21.6 1.3 1 0 0 1 1 1 1 Cytidylyltransferase family DUF423 PF04241.15 EGC40335.1 - 3.7 7.8 7.3 0.62 10.3 0.4 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF423) Acetyltransf_1 PF00583.25 EGC40336.1 - 2.4e-15 56.8 0.2 2.9e-15 56.5 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.7 EGC40336.1 - 5.7e-11 42.7 0.3 1.3e-10 41.6 0.3 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.7 EGC40336.1 - 2e-09 37.5 0.4 3e-09 36.9 0.4 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.7 EGC40336.1 - 2.2e-07 31.7 0.1 2.5e-07 31.4 0.1 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.7 EGC40336.1 - 3.2e-06 27.4 4.5 3.6e-06 27.2 4.5 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.6 EGC40336.1 - 0.00043 20.4 0.0 0.00096 19.2 0.0 1.6 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_15 PF17013.5 EGC40336.1 - 0.00081 18.9 1.7 0.0011 18.5 1.7 1.2 1 0 0 1 1 1 1 Putative acetyl-transferase FR47 PF08445.10 EGC40336.1 - 0.0063 16.5 0.0 0.011 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein TM2 PF05154.16 EGC40337.1 - 2.6e-07 30.9 4.5 3.4e-07 30.5 4.5 1.2 1 0 0 1 1 1 1 TM2 domain Stomoxyn PF11585.8 EGC40337.1 - 0.15 12.1 0.7 0.21 11.6 0.7 1.2 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TM2 PF05154.16 EGC40338.1 - 1e-11 45.0 6.6 1.4e-11 44.5 6.6 1.2 1 0 0 1 1 1 1 TM2 domain ATG22 PF11700.8 EGC40338.1 - 0.0042 15.8 0.0 0.0063 15.2 0.0 1.2 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like TctA PF01970.16 EGC40338.1 - 0.058 12.1 0.0 0.076 11.7 0.0 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family EIID-AGA PF03613.14 EGC40338.1 - 0.08 12.1 0.2 0.12 11.6 0.2 1.2 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component Hemerythrin PF01814.23 EGC40339.1 - 1.9e-10 41.5 0.6 3.2e-10 40.7 0.6 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain DUF1307 PF06998.11 EGC40339.1 - 0.0049 16.9 0.3 0.0082 16.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1307) Mer2 PF09074.10 EGC40339.1 - 0.013 15.4 0.7 0.018 14.9 0.7 1.3 1 0 0 1 1 1 0 Mer2 Fib_alpha PF08702.10 EGC40339.1 - 0.072 13.3 0.4 0.16 12.2 0.2 1.7 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Kinesin PF00225.23 EGC40342.1 - 0.1 11.5 0.0 0.1 11.5 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain Ank_2 PF12796.7 EGC40343.1 - 3.2e-13 50.0 4.0 7.1e-07 29.7 0.1 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.30 EGC40343.1 - 8.8e-13 48.1 2.4 0.0092 16.4 0.0 4.3 4 0 0 4 4 4 3 Ankyrin repeat Ank_4 PF13637.6 EGC40343.1 - 1.7e-10 41.2 1.2 7.2e-06 26.4 0.1 3.5 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.6 EGC40343.1 - 2.7e-10 39.6 1.9 0.025 15.1 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.6 EGC40343.1 - 5.2e-10 39.4 1.5 5.6e-07 29.7 1.1 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) DUF4611 PF15387.6 EGC40343.1 - 1.1 9.5 6.0 0.5 10.6 2.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2462 PF09495.10 EGC40344.1 - 1.9e-07 31.7 16.7 1.9e-07 31.7 16.7 1.6 1 1 0 2 2 2 1 Protein of unknown function (DUF2462) WBS_methylT PF12589.8 EGC40345.1 - 3.3e-21 75.8 7.7 5.4e-21 75.1 7.7 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.12 EGC40345.1 - 6.8e-10 39.5 0.0 1.2e-09 38.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC40345.1 - 7.6e-10 39.4 0.0 1.8e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC40345.1 - 0.00023 21.8 0.0 0.00071 20.3 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC40345.1 - 0.0012 18.7 0.0 0.0017 18.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.18 EGC40345.1 - 0.004 16.9 0.3 0.26 11.0 0.0 2.2 2 0 0 2 2 2 1 DNA methylase AdoMet_MTase PF07757.13 EGC40345.1 - 0.016 15.6 0.4 0.058 13.7 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Methyltransf_31 PF13847.6 EGC40345.1 - 0.063 13.1 0.0 0.1 12.4 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ras PF00071.22 EGC40346.1 - 3.4e-43 147.0 2.3 3.3e-23 82.1 0.2 2.4 2 0 0 2 2 2 2 Ras family Roc PF08477.13 EGC40346.1 - 3.5e-16 59.5 1.8 2.5e-08 34.2 0.1 3.2 3 0 0 3 3 3 2 Ras of Complex, Roc, domain of DAPkinase PH PF00169.29 EGC40346.1 - 2e-11 44.3 3.6 4.6e-11 43.2 3.6 1.7 1 0 0 1 1 1 1 PH domain Arf PF00025.21 EGC40346.1 - 1.9e-05 24.2 3.6 0.0027 17.2 0.3 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC40346.1 - 0.0003 20.9 0.1 0.00071 19.6 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase PH_8 PF15409.6 EGC40346.1 - 0.086 13.1 0.9 0.3 11.4 0.9 2.0 1 1 0 1 1 1 0 Pleckstrin homology domain TMEM189_B_dmain PF10520.9 EGC40347.1 - 4.1e-69 232.1 4.7 7.3e-69 231.3 4.7 1.4 1 0 0 1 1 1 1 B domain of TMEM189, localisation domain Folate_carrier PF01770.18 EGC40347.1 - 0.0022 16.8 1.9 0.0037 16.1 1.9 1.3 1 0 0 1 1 1 1 Reduced folate carrier EMC3_TMCO1 PF01956.16 EGC40347.1 - 0.0025 17.6 1.0 0.005 16.6 1.0 1.5 1 0 0 1 1 1 1 Integral membrane protein EMC3/TMCO1-like Ctr PF04145.15 EGC40347.1 - 0.0031 18.1 0.2 0.0031 18.1 0.2 1.6 2 0 0 2 2 2 1 Ctr copper transporter family DUF2370 PF10176.9 EGC40347.1 - 0.01 15.5 0.7 0.016 14.8 0.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) AIF_C PF14721.6 EGC40347.1 - 0.12 12.7 3.9 0.22 11.9 3.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4181 PF13789.6 EGC40347.1 - 0.15 12.3 4.8 0.25 11.6 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4181) DUF853 PF05872.12 EGC40347.1 - 0.51 8.9 2.2 0.7 8.4 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) WD40 PF00400.32 EGC40348.1 - 4e-45 150.9 26.0 1.4e-07 32.1 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat ANAPC4_WD40 PF12894.7 EGC40348.1 - 4.2e-19 68.6 9.1 0.0015 18.8 0.1 6.7 1 1 6 7 7 7 6 Anaphase-promoting complex subunit 4 WD40 domain IKI3 PF04762.12 EGC40348.1 - 0.0013 16.9 8.2 0.079 11.0 0.3 3.1 2 1 1 3 3 3 3 IKI3 family Nucleoporin_N PF08801.11 EGC40348.1 - 0.002 16.9 3.0 0.17 10.6 0.0 3.4 2 2 0 3 3 3 2 Nup133 N terminal like ABC_membrane PF00664.23 EGC40349.1 - 2.6e-28 99.4 20.1 4.7e-28 98.6 20.1 1.5 1 1 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.27 EGC40349.1 - 2.5e-13 50.7 0.0 5.4e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter MRAP PF15183.6 EGC40349.1 - 0.028 14.4 0.5 0.18 11.8 0.5 2.4 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family PBP1_TM PF14812.6 EGC40349.1 - 3 8.3 5.2 23 5.4 1.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal NTP_transf_7 PF07984.12 EGC40350.1 - 7.1e-25 87.9 3.8 1.9e-11 43.8 0.0 3.2 3 0 0 3 3 3 3 Nucleotidyltransferase Peptidase_C39_2 PF13529.6 EGC40351.1 - 5.8e-18 65.8 0.0 1.3e-17 64.7 0.0 1.6 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C70 PF12385.8 EGC40351.1 - 9.4e-15 54.9 0.0 1.6e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Papain-like cysteine protease AvrRpt2 Peptidase_C39 PF03412.15 EGC40351.1 - 5.7e-08 32.6 0.0 0.00019 21.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase C39 family Guanylate_cyc_2 PF09778.9 EGC40351.1 - 3.1e-06 26.7 0.1 0.11 11.9 0.0 2.6 2 1 1 3 3 3 2 Guanylylate cyclase DUF3335 PF11814.8 EGC40351.1 - 2.7e-05 23.7 0.0 0.011 15.2 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C10 PF01640.17 EGC40351.1 - 0.043 14.1 0.1 0.23 11.8 0.0 2.0 2 0 0 2 2 2 0 Peptidase C10 family Phytochelatin PF05023.14 EGC40351.1 - 0.083 12.1 0.0 13 4.9 0.0 2.8 3 0 0 3 3 3 0 Phytochelatin synthase p450 PF00067.22 EGC40353.1 - 2.7e-80 270.4 0.2 3e-80 270.2 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chordopox_G3 PF06129.12 EGC40353.1 - 0.69 10.6 4.7 5 7.9 0.3 3.3 4 0 0 4 4 4 0 Chordopoxvirus G3 protein FNIP PF05725.12 EGC40355.1 - 1.7e-11 44.1 20.6 4.7e-06 26.7 0.3 6.8 3 2 2 5 5 5 4 FNIP Repeat F5_F8_type_C PF00754.25 EGC40356.1 - 2.1e-26 92.5 2.2 3.2e-26 91.9 1.0 1.8 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.10 EGC40356.1 - 5e-20 71.5 1.7 1.7e-19 69.7 0.5 2.3 2 1 0 2 2 2 1 H-type lectin domain PPL5 PF18168.1 EGC40358.1 - 1.1 8.5 18.8 1.4 8.2 18.8 1.2 1 0 0 1 1 1 0 Prim-pol family 5 Tweety PF04906.13 EGC40359.1 - 1.9e-12 46.6 1.5 1.6e-09 37.0 1.0 2.4 2 0 0 2 2 2 2 Tweety Prominin PF05478.11 EGC40359.1 - 0.0027 15.8 3.1 0.11 10.5 0.1 2.5 2 1 0 2 2 2 2 Prominin Na_H_antiporter PF03553.14 EGC40359.1 - 0.0029 16.9 4.3 0.44 9.7 4.3 2.4 1 1 0 1 1 1 1 Na+/H+ antiporter family DUF1634 PF07843.11 EGC40359.1 - 0.0087 16.1 1.2 0.0087 16.1 1.2 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1634) Pex24p PF06398.11 EGC40359.1 - 0.062 12.3 6.2 0.84 8.5 4.0 3.1 2 1 1 3 3 3 0 Integral peroxisomal membrane peroxin DUF4834 PF16118.5 EGC40359.1 - 0.098 13.6 16.2 3.4 8.7 0.5 3.7 3 1 1 4 4 4 0 Domain of unknown function (DUF4834) EphA2_TM PF14575.6 EGC40359.1 - 0.11 13.4 0.4 5.8 7.9 0.1 3.1 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TMEM154 PF15102.6 EGC40359.1 - 0.15 12.0 3.4 0.26 11.2 0.1 2.9 3 0 0 3 3 3 0 TMEM154 protein family S_4TM PF18159.1 EGC40359.1 - 0.38 10.0 8.1 1.7 7.9 0.0 3.0 1 1 2 3 3 3 0 SMODS-associating 4TM effector domain Tetraspanin PF00335.20 EGC40359.1 - 0.54 9.9 14.1 0.097 12.4 0.8 3.5 2 1 0 3 3 3 0 Tetraspanin family SQHop_cyclase_C PF13243.6 EGC40360.1 - 6.1e-66 222.7 0.0 3.5e-59 200.5 0.0 2.9 2 1 1 3 3 3 2 Squalene-hopene cyclase C-terminal domain SQHop_cyclase_N PF13249.6 EGC40360.1 - 4.5e-50 170.4 0.0 1.4e-43 149.1 0.0 4.1 3 1 2 5 5 5 4 Squalene-hopene cyclase N-terminal domain Prenyltrans PF00432.21 EGC40360.1 - 6.4e-38 128.2 1.7 1.1e-09 37.9 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat TED_complement PF07678.14 EGC40360.1 - 2.5e-05 23.5 1.2 5.2 6.0 0.0 5.1 3 1 2 5 5 5 3 A-macroglobulin TED domain Pec_lyase PF09492.10 EGC40360.1 - 4.1e-05 23.0 0.4 0.21 10.9 0.0 4.3 4 1 0 4 4 4 1 Pectic acid lyase Chromo PF00385.24 EGC40361.1 - 5.6e-07 29.4 1.2 6.9e-07 29.1 1.2 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.19 EGC40361.1 - 0.00081 19.4 0.2 0.00099 19.2 0.2 1.2 1 0 0 1 1 1 1 Chromo shadow domain Pkinase PF00069.25 EGC40362.1 - 2e-70 237.2 2.0 2.2e-70 237.0 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40362.1 - 2.3e-47 161.4 0.0 5e-47 160.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.28 EGC40362.1 - 5.3e-18 65.1 0.9 4.8e-17 62.1 0.5 3.1 2 0 0 2 2 2 1 P21-Rho-binding domain Pox_TAA1 PF03295.14 EGC40362.1 - 0.072 13.0 0.1 0.59 10.1 0.0 2.2 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal ABC2_membrane PF01061.24 EGC40363.1 - 2.9e-37 128.1 19.7 2.9e-37 128.1 19.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.27 EGC40363.1 - 8e-27 94.4 0.0 1.9e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.6 EGC40363.1 - 8.6e-09 35.6 0.0 0.0034 17.2 0.0 2.3 2 0 0 2 2 2 2 AAA domain, putative AbiEii toxin, Type IV TA system SMC_N PF02463.19 EGC40363.1 - 0.00049 19.6 0.1 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.6 EGC40363.1 - 0.00083 19.6 0.0 0.0059 16.9 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.6 EGC40363.1 - 0.0015 18.9 0.0 0.0031 17.9 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_29 PF13555.6 EGC40363.1 - 0.0024 17.6 0.3 0.0064 16.2 0.2 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain ATPase_2 PF01637.18 EGC40363.1 - 0.0028 17.6 0.0 0.0052 16.7 0.0 1.4 1 0 0 1 1 1 1 ATPase domain predominantly from Archaea AAA_18 PF13238.6 EGC40363.1 - 0.0034 17.9 0.0 0.0095 16.5 0.0 1.8 1 0 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC40363.1 - 0.0046 16.9 0.4 0.012 15.5 0.4 1.7 1 0 0 1 1 1 1 RsgA GTPase AAA PF00004.29 EGC40363.1 - 0.006 17.0 0.0 0.33 11.4 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.6 EGC40363.1 - 0.0069 16.0 0.0 0.055 13.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain RecA PF00154.21 EGC40363.1 - 0.012 15.1 0.1 0.036 13.5 0.0 1.9 2 0 0 2 2 2 0 recA bacterial DNA recombination protein AAA_23 PF13476.6 EGC40363.1 - 0.017 15.7 0.0 0.043 14.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain T2SSE PF00437.20 EGC40363.1 - 0.017 14.2 0.2 0.03 13.4 0.2 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein cobW PF02492.19 EGC40363.1 - 0.018 14.7 0.0 0.031 13.9 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.6 EGC40363.1 - 0.03 14.6 0.0 0.19 12.0 0.0 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.6 EGC40363.1 - 0.031 14.4 0.1 0.1 12.8 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.6 EGC40363.1 - 0.044 14.0 0.1 0.078 13.2 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.12 EGC40363.1 - 0.1 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 NACHT domain Rad17 PF03215.15 EGC40363.1 - 0.13 12.2 0.0 0.45 10.4 0.0 1.9 2 0 0 2 2 1 0 Rad17 P-loop domain Pkinase PF00069.25 EGC40365.1 - 9.7e-34 116.9 0.9 1.3e-32 113.3 0.9 2.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40365.1 - 3.3e-18 65.9 0.0 1.9e-17 63.4 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.6 EGC40365.1 - 3e-10 40.2 4.8 0.014 15.7 0.5 4.8 3 2 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC40365.1 - 1.9e-09 36.9 7.9 0.043 13.9 0.1 7.1 8 0 0 8 8 7 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC40365.1 - 8.9e-08 31.6 8.0 0.04 13.7 0.3 5.7 6 0 0 6 6 6 3 Tetratricopeptide repeat Pkinase_fungal PF17667.1 EGC40365.1 - 1.9e-07 30.2 0.1 3.6e-07 29.3 0.1 1.4 1 0 0 1 1 1 1 Fungal protein kinase TPR_10 PF13374.6 EGC40365.1 - 0.00056 19.7 1.4 0.39 10.7 0.2 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat Sigma_reg_N PF13800.6 EGC40365.1 - 0.0019 18.4 0.4 0.0068 16.7 0.4 2.0 1 0 0 1 1 1 1 Sigma factor regulator N-terminal TPR_8 PF13181.6 EGC40365.1 - 0.0026 17.8 6.8 23 5.5 0.0 6.2 6 1 0 6 6 5 0 Tetratricopeptide repeat DUF1635 PF07795.11 EGC40365.1 - 0.0037 17.1 1.0 0.0069 16.3 1.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1635) TPR_16 PF13432.6 EGC40365.1 - 0.0039 17.8 1.7 1.2 9.9 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat Kdo PF06293.14 EGC40365.1 - 0.005 16.2 0.2 0.01 15.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_6 PF13174.6 EGC40365.1 - 0.0051 17.4 2.9 7.1 7.5 0.0 5.5 5 0 0 5 5 5 1 Tetratricopeptide repeat APH PF01636.23 EGC40365.1 - 0.0051 16.8 0.0 0.008 16.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF3856 PF12968.7 EGC40365.1 - 0.01 15.9 0.1 0.2 11.7 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) ANAPC3 PF12895.7 EGC40365.1 - 0.012 15.9 5.8 10 6.4 0.0 3.9 2 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 RIO1 PF01163.22 EGC40365.1 - 0.016 14.8 0.5 0.061 12.9 0.0 2.1 2 0 0 2 2 2 0 RIO1 family DUF627 PF04781.12 EGC40365.1 - 0.022 14.8 0.0 12 6.0 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF627) TPR_7 PF13176.6 EGC40365.1 - 0.046 13.8 3.2 4.6 7.5 0.2 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Kinase-like PF14531.6 EGC40365.1 - 0.054 12.8 0.0 0.12 11.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like FeoB_Cyto PF17910.1 EGC40365.1 - 0.07 13.7 0.1 2.7 8.6 0.1 3.1 2 0 0 2 2 2 0 FeoB cytosolic helical domain TPR_14 PF13428.6 EGC40365.1 - 0.17 12.8 0.0 1e+02 4.1 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat DUF3285 PF11688.8 EGC40365.1 - 2.8 7.9 5.0 3.4 7.6 0.6 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) DUF3430 PF11912.8 EGC40366.1 - 5.3e-31 108.3 24.6 5.3e-31 108.3 24.6 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) TPR_12 PF13424.6 EGC40367.1 - 3e-12 46.6 1.4 7.4e-05 23.0 0.1 2.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.28 EGC40367.1 - 6.2e-09 35.3 3.1 0.0057 16.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.17 EGC40367.1 - 3.7e-06 26.6 1.1 0.32 11.2 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.6 EGC40367.1 - 1.4e-05 24.8 0.5 1.9 8.7 0.0 3.6 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.6 EGC40367.1 - 5.7e-05 23.0 10.2 2 8.8 0.0 5.3 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_10 PF13374.6 EGC40367.1 - 0.0019 18.0 0.1 0.63 10.0 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF1947 PF09183.10 EGC40367.1 - 0.048 14.0 2.6 0.37 11.1 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1947) MIT PF04212.18 EGC40367.1 - 0.17 12.0 2.4 7.2 6.8 0.1 3.4 4 0 0 4 4 4 0 MIT (microtubule interacting and transport) domain Prefoldin PF02996.17 EGC40367.1 - 0.26 11.2 3.9 5.5 6.9 0.2 3.2 3 1 0 3 3 3 0 Prefoldin subunit TIG PF01833.24 EGC40368.1 - 1.8e-09 37.6 2.8 1.3e-05 25.2 0.3 2.9 2 0 0 2 2 2 2 IPT/TIG domain FYVE_2 PF02318.16 EGC40368.1 - 1.8e-07 31.4 5.8 3.6e-07 30.4 5.8 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger FYVE PF01363.21 EGC40368.1 - 2.8e-06 27.4 5.6 5.2e-06 26.5 5.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-piccolo PF05715.13 EGC40368.1 - 0.24 11.6 7.9 0.62 10.2 7.9 1.8 1 1 0 1 1 1 0 Piccolo Zn-finger C1_2 PF03107.16 EGC40368.1 - 0.36 11.2 7.7 0.42 11.0 3.9 2.3 2 0 0 2 2 2 0 C1 domain SHQ1 PF04925.15 EGC40369.1 - 4.3e-65 218.6 6.0 7.1e-65 217.9 6.0 1.4 1 0 0 1 1 1 1 SHQ1 protein Presenilin PF01080.17 EGC40369.1 - 0.56 8.9 5.6 1 8.0 5.6 1.4 1 0 0 1 1 1 0 Presenilin TRM13 PF05206.14 EGC40369.1 - 0.69 9.4 9.5 0.47 9.9 0.3 2.4 2 0 0 2 2 2 0 Methyltransferase TRM13 Band_3_cyto PF07565.13 EGC40369.1 - 0.81 9.4 6.2 1.8 8.3 6.2 1.6 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Tir_receptor_C PF07489.11 EGC40370.1 - 0.00095 19.2 0.9 0.00095 19.2 0.9 1.8 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus FNIP PF05725.12 EGC40371.1 - 9.2e-19 67.3 7.0 1.6e-11 44.2 0.2 2.8 2 1 0 3 3 3 2 FNIP Repeat LRR_5 PF13306.6 EGC40371.1 - 0.078 12.9 0.0 0.12 12.3 0.0 1.3 1 1 0 1 1 1 0 BspA type Leucine rich repeat region (6 copies) HEAT PF02985.22 EGC40372.1 - 2.7e-08 33.4 16.9 0.035 14.3 0.0 9.7 13 0 0 13 13 10 2 HEAT repeat HEAT_EZ PF13513.6 EGC40372.1 - 5.8e-08 33.1 0.0 0.0097 16.4 0.0 6.4 6 0 0 6 6 6 1 HEAT-like repeat HEAT_2 PF13646.6 EGC40372.1 - 7.8e-08 32.6 0.0 3.4 8.1 0.0 6.4 6 2 3 9 9 9 3 HEAT repeats Cnd1 PF12717.7 EGC40372.1 - 8.9e-08 32.3 16.3 1.1e-05 25.5 0.2 5.9 3 1 3 6 6 6 3 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.7 EGC40372.1 - 2.4e-06 28.1 10.8 0.00022 21.8 0.2 6.1 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region DUF3385 PF11865.8 EGC40372.1 - 7.4e-06 26.0 8.5 0.066 13.1 0.0 6.1 4 2 0 5 5 5 1 Domain of unknown function (DUF3385) IBN_N PF03810.19 EGC40372.1 - 5.5e-05 23.0 3.2 0.00013 21.8 1.1 2.9 3 0 0 3 3 3 1 Importin-beta N-terminal domain Sec7_N PF12783.7 EGC40372.1 - 0.0016 18.4 16.7 0.39 10.6 0.6 6.9 4 2 1 6 6 6 3 Guanine nucleotide exchange factor in Golgi transport N-terminal RTP1_C1 PF10363.9 EGC40372.1 - 0.0016 18.6 4.4 9.9 6.4 0.0 5.2 3 2 2 5 5 5 1 Required for nuclear transport of RNA pol II C-terminus 1 CLASP_N PF12348.8 EGC40372.1 - 0.0052 16.4 5.8 3.6 7.1 0.0 4.3 4 0 0 4 4 4 2 CLASP N terminal Xpo1 PF08389.12 EGC40372.1 - 0.22 11.6 19.6 0.22 11.6 0.2 6.5 7 1 0 8 8 8 0 Exportin 1-like protein CENP-B_dimeris PF09026.10 EGC40372.1 - 2.5 8.5 15.5 1.9 8.9 10.1 2.6 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Astro_capsid_p PF12226.8 EGC40372.1 - 3.3 6.8 8.4 6.3 5.8 8.4 1.3 1 0 0 1 1 1 0 Turkey astrovirus capsid protein DEAD PF00270.29 EGC40373.1 - 7e-37 126.9 0.1 1.1e-36 126.2 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.31 EGC40373.1 - 8.1e-29 100.2 0.3 1.8e-25 89.4 0.1 2.8 3 0 0 3 3 3 2 Helicase conserved C-terminal domain ResIII PF04851.15 EGC40373.1 - 2.1e-07 31.1 0.0 4.1e-07 30.2 0.0 1.5 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.6 EGC40373.1 - 5.3e-06 26.0 0.0 1e-05 25.0 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit DUF5402 PF17393.2 EGC40373.1 - 0.045 13.7 0.1 0.53 10.2 0.0 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF5402) ARPC4 PF05856.12 EGC40374.1 - 4.2e-76 254.2 6.2 4.7e-76 254.1 6.2 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) DUF447 PF04289.12 EGC40374.1 - 0.041 13.7 0.3 0.06 13.1 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF447) Mak10 PF04112.13 EGC40375.1 - 1.4e-22 80.0 1.5 5.5e-19 68.3 0.1 3.3 2 1 1 3 3 3 2 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase Sugarporin_N PF11471.8 EGC40375.1 - 0.13 12.2 0.1 0.38 10.7 0.1 1.7 1 0 0 1 1 1 0 Maltoporin periplasmic N-terminal extension FNIP PF05725.12 EGC40376.1 - 2e-35 120.7 34.5 5.4e-10 39.3 4.0 5.5 3 2 3 6 6 6 5 FNIP Repeat Secretin_N_2 PF07655.13 EGC40376.1 - 0.73 10.4 8.6 1.3 9.6 8.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain ACPS PF01648.20 EGC40378.1 - 1.9e-30 105.3 0.1 2.3e-30 105.1 0.1 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily 4PPT_N PF17837.1 EGC40378.1 - 7.3e-05 22.8 0.1 0.019 15.1 0.0 2.2 2 0 0 2 2 2 2 4'-phosphopantetheinyl transferase N-terminal domain DUF5461 PF17545.2 EGC40378.1 - 0.03 14.6 0.1 0.92 9.9 0.0 2.2 2 1 0 2 2 2 0 Family of unknown function (DUF5461) F-box PF00646.33 EGC40379.1 - 0.025 14.4 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain Secretin_N_2 PF07655.13 EGC40379.1 - 0.67 10.5 18.8 1.4 9.5 18.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain Ras PF00071.22 EGC40380.1 - 1.2e-46 158.3 0.2 1.8e-46 157.7 0.2 1.3 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC40380.1 - 3.8e-22 78.8 0.6 9.6e-22 77.5 0.0 1.9 2 0 0 2 2 2 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC40380.1 - 1.6e-09 37.4 0.1 3e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.27 EGC40380.1 - 0.0075 15.8 1.0 0.0075 15.8 1.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_28 PF13521.6 EGC40380.1 - 0.041 14.1 0.0 0.064 13.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain FAM199X PF15814.5 EGC40380.1 - 0.099 11.7 13.3 0.14 11.2 13.3 1.2 1 0 0 1 1 1 0 Protein family FAM199X Hist_deacetyl PF00850.19 EGC40381.1 - 2.8e-81 273.3 0.0 3.7e-81 273.0 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FNIP PF05725.12 EGC40384.1 - 0.00072 19.7 43.5 0.034 14.3 0.6 10.0 7 4 1 8 8 8 4 FNIP Repeat PBP_N PF17093.5 EGC40384.1 - 0.008 16.4 0.1 0.013 15.8 0.1 1.3 1 0 0 1 1 1 1 Penicillin-binding protein N-terminus DUF3586 PF12131.8 EGC40385.1 - 7.1 6.9 14.4 0.26 11.5 1.5 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) DUF4419 PF14388.6 EGC40386.1 - 6.8e-94 314.7 1.4 7.9e-94 314.5 1.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FNIP PF05725.12 EGC40387.1 - 2.8e-128 417.9 175.1 3.6e-12 46.3 1.3 20.8 9 2 12 21 21 21 20 FNIP Repeat Pkinase PF00069.25 EGC40387.1 - 3.1e-37 128.4 0.1 1.1e-36 126.6 0.1 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40387.1 - 4.3e-26 91.7 0.0 6.7e-26 91.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.6 EGC40387.1 - 5.9e-06 25.8 0.0 9.9e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Kinase-like TFIIA_gamma_N PF02268.16 EGC40387.1 - 0.00033 20.6 0.5 5.3 7.1 0.0 6.0 6 0 0 6 6 6 1 Transcription initiation factor IIA, gamma subunit, helical domain Pkinase_fungal PF17667.1 EGC40387.1 - 0.0033 16.3 0.1 0.005 15.7 0.1 1.2 1 0 0 1 1 1 1 Fungal protein kinase GED PF02212.18 EGC40387.1 - 0.0063 16.6 0.9 0.94 9.7 0.1 4.0 3 0 0 3 3 3 1 Dynamin GTPase effector domain APH PF01636.23 EGC40387.1 - 0.054 13.4 0.0 0.084 12.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-RING_2 PF13639.6 EGC40388.1 - 2.6e-09 37.2 10.9 4.7e-09 36.4 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC40388.1 - 1.1e-08 34.7 10.8 2e-08 33.9 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC40388.1 - 1.7e-08 34.2 11.7 4.5e-08 32.8 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC40388.1 - 1.7e-07 31.4 7.7 4.8e-07 30.0 7.7 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC40388.1 - 3e-06 27.0 7.5 5e-06 26.3 7.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC40388.1 - 9.9e-05 22.3 5.0 0.00023 21.1 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC40388.1 - 0.00022 21.1 10.9 0.00042 20.2 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC40388.1 - 0.00036 20.6 8.5 0.00098 19.2 8.5 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.6 EGC40388.1 - 0.0013 18.5 7.2 0.003 17.4 7.2 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC40388.1 - 0.012 15.4 9.7 0.026 14.3 9.7 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC40388.1 - 0.02 14.9 2.9 0.042 13.9 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger CAF-1_p150 PF11600.8 EGC40388.1 - 0.18 11.5 37.1 0.29 10.8 37.1 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal TFIIA PF03153.13 EGC40388.1 - 0.61 10.0 30.5 0.88 9.5 30.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_11 PF17123.5 EGC40388.1 - 1.7 8.4 10.6 3.6 7.4 10.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger zf-MIZ PF02891.20 EGC40388.1 - 2.6 7.9 8.1 5.3 6.9 8.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Zn_ribbon_17 PF17120.5 EGC40388.1 - 2.6 7.7 7.6 4.3 7.0 7.6 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type IBR PF01485.21 EGC40388.1 - 7.5 6.9 10.7 43 4.4 10.4 2.5 1 1 1 2 2 2 0 IBR domain, a half RING-finger domain Connexin PF00029.19 EGC40388.1 - 8.6 6.0 15.2 0.33 10.7 7.2 2.3 2 0 0 2 2 2 0 Connexin zf-RING_2 PF13639.6 EGC40389.1 - 2.9e-09 37.1 10.9 5.1e-09 36.3 10.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC40389.1 - 1.3e-08 34.6 10.8 2.1e-08 33.8 10.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC40389.1 - 1.9e-08 34.1 11.7 4.9e-08 32.7 11.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC40389.1 - 2.6e-07 30.8 8.0 7e-07 29.4 8.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-C3HC4_3 PF13920.6 EGC40389.1 - 4.9e-06 26.3 7.9 8e-06 25.6 7.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC40389.1 - 0.00011 22.2 5.0 0.00025 21.0 5.0 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.6 EGC40389.1 - 0.00024 21.0 10.9 0.00045 20.1 10.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.6 EGC40389.1 - 0.00045 20.3 8.5 0.0011 19.1 8.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING AAA_23 PF13476.6 EGC40389.1 - 0.0024 18.4 16.1 0.0024 18.4 16.1 2.3 2 0 0 2 2 2 1 AAA domain Prok-RING_4 PF14447.6 EGC40389.1 - 0.0032 17.3 7.2 0.0032 17.3 7.2 1.9 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_4 PF14570.6 EGC40389.1 - 0.011 15.5 9.7 0.028 14.2 9.7 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-ANAPC11 PF12861.7 EGC40389.1 - 0.02 14.9 3.0 0.047 13.7 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_11 PF17123.5 EGC40389.1 - 1.8 8.4 10.6 3.9 7.3 10.6 1.6 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC40389.1 - 1.9 8.2 7.8 3 7.5 7.8 1.3 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type DUF1272 PF06906.11 EGC40389.1 - 2.1 8.5 5.9 3.9 7.6 5.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MIZ PF02891.20 EGC40389.1 - 3.5 7.5 8.3 5.8 6.7 8.3 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger UPF0228 PF05727.11 EGC40390.1 - 0.026 14.4 0.3 0.03 14.1 0.3 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0228) PHD_like PF12910.7 EGC40390.1 - 0.11 12.5 0.2 0.13 12.3 0.2 1.0 1 0 0 1 1 1 0 Antitoxin of toxin-antitoxin, RelE / RelB, TA system NAD_binding_10 PF13460.6 EGC40391.1 - 7.4e-09 35.8 0.0 1e-08 35.3 0.0 1.2 1 0 0 1 1 1 1 NAD(P)H-binding NAD_binding_4 PF07993.12 EGC40391.1 - 0.00018 20.8 0.0 0.0051 16.0 0.0 2.1 1 1 0 2 2 2 2 Male sterility protein Semialdhyde_dh PF01118.24 EGC40391.1 - 0.0099 16.3 0.0 0.022 15.2 0.0 1.6 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain Aminotran_5 PF00266.19 EGC40392.1 - 9.7e-43 146.5 0.0 1.1e-42 146.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Ig_4 PF16680.5 EGC40392.1 - 0.11 12.8 0.0 0.32 11.3 0.0 1.8 2 0 0 2 2 2 0 T-cell surface glycoprotein CD3 delta chain HEAT_EZ PF13513.6 EGC40393.1 - 4.5e-31 106.9 0.4 2.2e-14 53.6 0.0 9.8 11 0 0 11 11 11 4 HEAT-like repeat HEAT PF02985.22 EGC40393.1 - 4.7e-25 85.5 1.0 0.00027 20.9 0.0 10.6 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.6 EGC40393.1 - 9.7e-16 57.9 0.0 4.5e-05 23.8 0.0 6.3 3 2 5 8 8 8 5 HEAT repeats Cnd1 PF12717.7 EGC40393.1 - 2.8e-14 53.5 0.3 0.0025 17.9 0.0 5.2 3 2 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 IBN_N PF03810.19 EGC40393.1 - 2.1e-11 43.6 0.0 1.3e-10 41.0 0.0 2.5 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.7 EGC40393.1 - 1.5e-10 41.6 0.0 0.016 15.8 0.1 5.4 3 2 3 6 6 6 3 Vacuolar 14 Fab1-binding region Arm PF00514.23 EGC40393.1 - 3.3e-10 39.6 3.8 0.51 10.5 0.0 7.5 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat MMS19_C PF12460.8 EGC40393.1 - 5.6e-08 32.3 8.6 0.0067 15.6 0.1 5.2 3 2 2 5 5 5 2 RNAPII transcription regulator C-terminal DUF3385 PF11865.8 EGC40393.1 - 0.00013 21.9 0.7 2.6 7.9 0.0 5.7 5 1 1 6 6 6 1 Domain of unknown function (DUF3385) RIX1 PF08167.12 EGC40393.1 - 0.00062 19.6 0.5 0.67 9.7 0.0 4.1 3 1 1 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.12 EGC40393.1 - 0.0019 18.3 0.4 0.32 11.0 0.2 4.2 3 1 0 3 3 3 1 Exportin 1-like protein Dopey_N PF04118.14 EGC40393.1 - 0.0091 15.1 6.9 1.9 7.5 0.2 4.4 3 1 2 5 5 5 2 Dopey, N-terminal HEAT_PBS PF03130.16 EGC40393.1 - 0.088 13.5 0.0 4.9 8.1 0.0 3.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat PBP1_TM PF14812.6 EGC40393.1 - 1.3 9.5 4.9 2.7 8.4 4.9 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PQ-loop PF04193.14 EGC40394.1 - 8e-21 73.6 6.2 2.8e-11 43.0 1.5 3.2 4 0 0 4 4 4 2 PQ loop repeat CTV_P6 PF06706.11 EGC40394.1 - 0.061 13.0 0.1 1.7 8.4 0.0 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein MtN3_slv PF03083.16 EGC40394.1 - 0.08 13.0 11.2 0.1 12.6 3.8 3.3 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange LapA_dom PF06305.11 EGC40394.1 - 0.81 9.6 0.0 0.81 9.6 0.0 3.5 4 1 0 4 4 4 0 Lipopolysaccharide assembly protein A domain DUF443 PF04276.12 EGC40394.1 - 1.9 8.3 10.6 0.49 10.2 3.5 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF443) Oxysterol_BP PF01237.18 EGC40395.1 - 9.9e-33 113.5 13.1 8.2e-30 103.9 13.1 2.0 1 1 0 1 1 1 1 Oxysterol-binding protein Parvo_coat_N PF08398.10 EGC40395.1 - 0.097 12.8 0.0 0.21 11.8 0.0 1.6 1 0 0 1 1 1 0 Parvovirus coat protein VP1 Oxysterol_BP PF01237.18 EGC40396.1 - 2.4e-44 151.7 14.7 4.8e-41 140.8 0.8 2.3 1 1 1 2 2 2 2 Oxysterol-binding protein B3 PF02362.21 EGC40396.1 - 0.009 15.9 2.7 0.015 15.1 0.1 2.3 2 0 0 2 2 2 1 B3 DNA binding domain FAM60A PF15396.6 EGC40396.1 - 0.84 9.6 7.9 0.62 10.0 4.3 2.2 2 0 0 2 2 2 0 Protein Family FAM60A Band_7 PF01145.25 EGC40397.1 - 2.3e-37 128.7 1.1 4e-37 128.0 1.1 1.4 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.6 EGC40397.1 - 0.013 15.2 0.4 0.022 14.5 0.4 1.4 1 0 0 1 1 1 0 SPFH domain-Band 7 family RNase_HII PF01351.18 EGC40397.1 - 0.15 11.9 3.9 6.9 6.4 0.1 2.4 1 1 1 2 2 2 0 Ribonuclease HII Prenyltrans PF00432.21 EGC40398.1 - 2.1e-22 78.6 1.0 1.3e-09 37.6 0.0 6.1 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat SnoaL_2 PF12680.7 EGC40399.1 - 0.0021 18.7 0.0 0.0024 18.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.12 EGC40399.1 - 0.0026 17.5 0.0 0.0059 16.4 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Longin PF13774.6 EGC40400.1 - 2.5e-18 65.9 1.8 6.4e-18 64.6 1.8 1.8 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.21 EGC40400.1 - 6.7e-15 54.6 0.4 1.2e-14 53.8 0.4 1.4 1 0 0 1 1 1 1 Synaptobrevin TetR_C_29 PF17938.1 EGC40400.1 - 0.0088 16.1 0.1 9.8 6.3 0.0 3.0 3 0 0 3 3 3 2 Tetracyclin repressor-like, C-terminal domain DUF829 PF05705.14 EGC40400.1 - 0.062 13.2 0.0 0.13 12.2 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) adh_short PF00106.25 EGC40401.1 - 7.9e-34 116.8 0.0 1.1e-33 116.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC40401.1 - 2e-23 83.2 0.0 2.7e-23 82.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC40401.1 - 2.9e-05 24.1 0.0 5.1e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 KR domain SIR2 PF02146.17 EGC40402.1 - 9.7e-25 87.5 0.0 2.8e-24 86.0 0.0 1.7 2 0 0 2 2 2 1 Sir2 family SIR2_2 PF13289.6 EGC40402.1 - 0.0055 16.8 0.7 4.5 7.4 0.0 3.5 3 1 0 3 3 3 2 SIR2-like domain TPP_enzyme_M PF00205.22 EGC40402.1 - 0.019 14.7 0.0 0.12 12.1 0.0 2.1 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TACC_C PF05010.14 EGC40403.1 - 0.00085 19.2 2.5 0.0012 18.6 2.5 1.2 1 0 0 1 1 1 1 Transforming acidic coiled-coil-containing protein (TACC), C-terminal Trypan_PARP PF05887.11 EGC40404.1 - 3.6e-08 33.5 133.2 2.5e-05 24.3 63.8 5.3 2 1 3 6 6 6 4 Procyclic acidic repetitive protein (PARP) YqzL PF14006.6 EGC40404.1 - 0.23 11.8 0.0 0.23 11.8 0.0 4.0 4 0 0 4 4 4 0 YqzL-like protein DUF1084 PF06454.11 EGC40405.1 - 4.4e-07 29.6 29.3 9e-07 28.5 29.3 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) SAM_1 PF00536.30 EGC40405.1 - 0.00065 20.1 0.1 2 8.9 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) RabGAP-TBC PF00566.18 EGC40406.1 - 7.7e-53 179.3 1.7 7.7e-53 179.3 1.7 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Drf_GBD PF06371.13 EGC40406.1 - 0.057 13.0 1.1 0.12 11.9 0.3 2.0 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain DUF3439 PF11921.8 EGC40406.1 - 0.92 9.5 11.9 2.1 8.3 11.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.17 EGC40406.1 - 1.9 8.5 22.6 3 7.8 22.6 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RNase_P_p30 PF01876.16 EGC40407.1 - 6.4e-52 176.1 1.0 6.4e-52 176.1 1.0 1.9 2 0 0 2 2 2 1 RNase P subunit p30 CorC_HlyC PF03471.17 EGC40407.1 - 0.07 13.1 0.0 0.18 11.9 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain Choline_transpo PF04515.12 EGC40408.1 - 1.9e-37 129.2 31.3 2.3e-37 128.9 31.3 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter DUF3821 PF12863.7 EGC40409.1 - 0.019 14.8 0.7 0.049 13.5 0.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3821) GNAT_C PF18164.1 EGC40410.1 - 0.14 11.8 1.7 0.27 11.0 0.2 2.1 2 0 0 2 2 2 0 GNAT-like C-terminal domain CC2-LZ PF16516.5 EGC40410.1 - 3.4 8.1 22.1 6.7 7.2 14.2 3.4 2 1 0 2 2 2 0 Leucine zipper of domain CC2 of NEMO, NF-kappa-B essential modulator Phage_holin_4_1 PF05105.12 EGC40411.1 - 0.11 12.6 3.8 0.22 11.7 3.8 1.4 1 0 0 1 1 1 0 Bacteriophage holin family TatC PF00902.18 EGC40411.1 - 1.5 8.6 5.9 2.1 8.1 5.9 1.1 1 0 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Glyco_hydro_18 PF00704.28 EGC40412.1 - 0.01 15.6 0.4 0.015 15.0 0.4 1.6 1 1 0 1 1 1 0 Glycosyl hydrolases family 18 XRCC4 PF06632.12 EGC40413.1 - 9e-20 70.8 28.9 8.3e-19 67.6 28.9 2.1 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 PAXX PF15384.6 EGC40413.1 - 0.003 17.3 4.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 PAXX, PAralog of XRCC4 and XLF, also called C9orf142 XLF PF09302.11 EGC40413.1 - 0.68 10.1 18.2 0.49 10.5 10.6 3.4 1 1 1 2 2 2 0 XLF-Cernunnos, XRcc4-like factor, NHEJ component TPP_enzyme_N PF02776.18 EGC40414.1 - 3.6e-44 150.4 0.1 1.1e-43 148.8 0.0 1.8 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.21 EGC40414.1 - 1.6e-24 86.4 0.0 2e-23 82.9 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.22 EGC40414.1 - 1.2e-18 67.2 0.0 2.5e-18 66.2 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Ras PF00071.22 EGC40415.1 - 1.8e-43 147.9 0.1 2.2e-43 147.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Roc PF08477.13 EGC40415.1 - 1.5e-22 80.0 0.1 2.1e-22 79.6 0.1 1.2 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase Arf PF00025.21 EGC40415.1 - 4.3e-06 26.3 0.0 5.5e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.23 EGC40415.1 - 0.00011 22.3 0.0 0.00019 21.5 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.18 EGC40415.1 - 0.00012 21.5 0.0 0.00018 20.9 0.0 1.2 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.22 EGC40415.1 - 0.00035 20.9 0.1 0.0013 19.1 0.0 1.9 3 0 0 3 3 2 1 RNA helicase AAA_18 PF13238.6 EGC40415.1 - 0.00066 20.2 0.0 0.0012 19.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_24 PF13479.6 EGC40415.1 - 0.0018 18.0 0.1 0.0046 16.7 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.6 EGC40415.1 - 0.0041 17.4 0.0 0.014 15.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain RsgA_GTPase PF03193.16 EGC40415.1 - 0.013 15.4 0.0 0.1 12.5 0.0 2.0 2 0 0 2 2 2 0 RsgA GTPase AAA_7 PF12775.7 EGC40415.1 - 0.015 14.8 0.0 0.029 13.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing dynein motor region AAA_16 PF13191.6 EGC40415.1 - 0.019 15.3 0.0 0.023 15.1 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain NACHT PF05729.12 EGC40415.1 - 0.023 14.6 0.0 0.033 14.1 0.0 1.2 1 0 0 1 1 1 0 NACHT domain MCM PF00493.23 EGC40415.1 - 0.023 13.8 0.0 0.044 12.9 0.0 1.4 1 0 0 1 1 1 0 MCM P-loop domain Viral_helicase1 PF01443.18 EGC40415.1 - 0.024 14.4 0.0 0.037 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.13 EGC40415.1 - 0.031 13.5 0.0 0.055 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) TniB PF05621.11 EGC40415.1 - 0.039 13.4 0.0 0.06 12.7 0.0 1.3 1 0 0 1 1 1 0 Bacterial TniB protein ABC_tran PF00005.27 EGC40415.1 - 0.041 14.4 0.0 0.063 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.29 EGC40415.1 - 0.042 14.3 0.0 0.082 13.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PPL4 PF18188.1 EGC40415.1 - 0.082 12.8 0.1 0.16 11.9 0.1 1.4 1 0 0 1 1 1 0 Prim-pol 4 AAA_29 PF13555.6 EGC40415.1 - 0.14 12.0 0.0 0.34 10.7 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain GTP_EFTU PF00009.27 EGC40415.1 - 0.14 11.7 0.0 11 5.5 0.0 2.1 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain ELMO_CED12 PF04727.13 EGC40416.1 - 2.8e-47 161.1 0.1 2.8e-47 161.1 0.1 2.4 2 1 1 3 3 3 1 ELMO/CED-12 family Erf4 PF10256.9 EGC40417.1 - 0.0035 17.4 2.2 0.0035 17.4 2.2 2.6 2 2 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.9 EGC40417.1 - 0.0041 15.9 0.6 0.0057 15.5 0.6 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) MKT1_N PF12247.8 EGC40417.1 - 0.017 15.5 0.2 0.095 13.1 0.1 2.3 1 1 1 2 2 2 0 Temperature dependent protein affecting M2 dsRNA replication HTH_29 PF13551.6 EGC40418.1 - 0.00091 19.2 0.1 0.0028 17.6 0.0 1.8 2 0 0 2 2 2 1 Winged helix-turn helix HTH_23 PF13384.6 EGC40418.1 - 0.0012 18.6 0.0 0.0026 17.5 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.6 EGC40418.1 - 0.0087 16.2 0.0 0.016 15.4 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.18 EGC40418.1 - 0.029 14.3 0.0 0.062 13.2 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain Ribosomal_L14e PF01929.17 EGC40418.1 - 0.062 13.8 0.1 0.17 12.4 0.1 1.8 1 1 0 1 1 1 0 Ribosomal protein L14 HTH_Tnp_Tc3_2 PF01498.18 EGC40418.1 - 0.093 13.0 1.9 0.098 12.9 0.3 1.7 2 0 0 2 2 2 0 Transposase EF-hand_1 PF00036.32 EGC40419.1 - 0.0056 16.1 0.2 0.037 13.6 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.6 EGC40419.1 - 0.049 13.6 0.0 0.36 10.9 0.0 2.1 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.6 EGC40419.1 - 0.11 13.0 0.4 0.32 11.5 0.3 1.8 1 1 1 2 2 2 0 EF-hand domain pair Coiled PF05710.12 EGC40420.1 - 0.22 12.4 11.9 0.3 11.9 11.9 1.3 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.12 EGC40421.1 - 0.01 16.7 17.6 0.018 15.8 17.6 1.5 1 1 0 1 1 1 0 Coiled coil DnaJ-X PF14308.6 EGC40426.1 - 0.0065 15.9 6.9 0.013 15.0 6.9 1.5 1 0 0 1 1 1 1 X-domain of DnaJ-containing P-mevalo_kinase PF04275.14 EGC40426.1 - 1.6 8.7 10.2 0.23 11.4 5.5 1.9 2 0 0 2 2 2 0 Phosphomevalonate kinase Dynactin_p62 PF05502.13 EGC40426.1 - 1.6 7.4 13.2 2.9 6.5 9.0 2.0 2 0 0 2 2 2 0 Dynactin p62 family PT PF04886.12 EGC40427.1 - 0.0017 17.8 26.0 0.0037 16.8 26.0 1.5 1 0 0 1 1 1 1 PT repeat DUF4366 PF14283.6 EGC40427.1 - 0.83 9.7 8.6 2.2 8.3 8.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4366) Pkinase PF00069.25 EGC40428.1 - 7.2e-39 133.7 0.0 7.2e-39 133.7 0.0 3.4 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40428.1 - 7.3e-29 100.8 0.0 7.3e-29 100.8 0.0 2.1 2 1 1 3 3 3 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGC40428.1 - 1.5e-13 51.0 3.6 1.5e-13 51.0 3.6 3.5 2 1 1 3 3 3 1 Ribonuclease 2-5A Pkinase_fungal PF17667.1 EGC40428.1 - 0.00026 19.9 0.1 0.00026 19.9 0.1 3.9 3 1 0 4 4 4 2 Fungal protein kinase APH PF01636.23 EGC40428.1 - 0.16 11.9 0.0 0.16 11.9 0.0 2.0 2 1 0 2 2 2 0 Phosphotransferase enzyme family FNIP PF05725.12 EGC40429.1 - 1.5e-26 92.3 86.8 4.5e-09 36.3 1.4 12.8 9 3 3 12 12 12 9 FNIP Repeat P66_CC PF16563.5 EGC40429.1 - 0.049 13.2 0.2 0.14 11.8 0.2 1.8 1 0 0 1 1 1 0 Coiled-coil and interaction region of P66A and P66B with MBD2 PAP2 PF01569.21 EGC40431.1 - 2.4e-05 24.1 0.4 2.4e-05 24.1 0.4 2.4 2 1 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.6 EGC40431.1 - 0.0032 17.2 2.8 0.009 15.7 0.0 2.7 3 0 0 3 3 3 1 PAP2 superfamily Wzy_C_2 PF11846.8 EGC40431.1 - 0.46 10.4 3.5 0.76 9.7 1.6 2.0 2 0 0 2 2 2 0 Virulence factor membrane-bound polymerase, C-terminal FNIP PF05725.12 EGC40432.1 - 5.2e-40 135.4 96.4 4.6e-12 45.9 0.7 12.5 10 2 3 13 13 13 8 FNIP Repeat Glyco_hydro_65C PF03633.15 EGC40432.1 - 0.15 12.0 1.4 1.9e+02 2.1 0.0 5.2 6 0 0 6 6 6 0 Glycosyl hydrolase family 65, C-terminal domain Pkinase PF00069.25 EGC40433.1 - 9.6e-32 110.4 0.0 9.6e-32 110.4 0.0 2.7 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40433.1 - 4.5e-22 78.6 0.0 1.2e-21 77.1 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.12 EGC40433.1 - 1.2e-10 41.6 4.2 1.2e-10 41.6 4.2 2.6 2 1 0 2 2 2 1 Ribonuclease 2-5A Nop25 PF09805.9 EGC40433.1 - 2 8.9 21.0 3.7 8.0 21.0 1.4 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Putative_PNPOx PF01243.20 EGC40435.1 - 1.9e-22 79.3 0.0 2.9e-22 78.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNP_phzG_C PF10590.9 EGC40435.1 - 2.6e-16 59.4 1.7 6.9e-16 58.1 1.7 1.8 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.7 EGC40435.1 - 0.0012 19.4 0.1 0.0024 18.5 0.1 1.5 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FNIP PF05725.12 EGC40436.1 - 2.4e-13 50.0 14.8 2.1e-06 27.8 2.8 3.7 4 0 0 4 4 4 3 FNIP Repeat LRR_5 PF13306.6 EGC40436.1 - 1.8e-05 24.7 1.7 0.013 15.5 0.2 1.7 1 1 1 2 2 2 2 BspA type Leucine rich repeat region (6 copies) SapB_1 PF05184.15 EGC40437.1 - 1.4e-05 25.0 12.4 0.0027 17.7 0.2 4.3 4 1 0 4 4 4 2 Saposin-like type B, region 1 zinc_ribbon_4 PF13717.6 EGC40437.1 - 0.0025 17.7 2.4 2 8.4 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain SapB_2 PF03489.17 EGC40437.1 - 0.003 17.6 0.1 0.003 17.6 0.1 2.4 3 0 0 3 3 3 1 Saposin-like type B, region 2 SapB_2 PF03489.17 EGC40438.1 - 2.6e-13 49.8 3.5 3.4e-08 33.5 0.3 3.2 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC40438.1 - 1.7e-05 24.7 17.9 0.00014 21.8 0.3 5.0 5 1 0 5 5 5 2 Saposin-like type B, region 1 zinc_ribbon_4 PF13717.6 EGC40438.1 - 0.00027 20.8 1.7 0.52 10.3 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_12 PF11331.8 EGC40438.1 - 0.13 12.1 2.1 0.27 11.1 0.1 2.5 3 0 0 3 3 3 0 Probable zinc-ribbon domain zf-RanBP PF00641.18 EGC40438.1 - 0.44 9.9 4.0 14 5.1 0.3 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DUF3456 PF11938.8 EGC40438.1 - 1.3 9.6 8.9 9.3 6.7 0.6 3.1 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP DnaJ PF00226.31 EGC40439.1 - 6.8e-20 71.0 0.3 6.8e-20 71.0 0.3 2.5 3 0 0 3 3 3 1 DnaJ domain Mucin PF01456.17 EGC40439.1 - 4 7.4 24.5 8 6.5 24.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-CCHC PF00098.23 EGC40440.1 - 5.6e-05 23.0 2.0 0.00012 21.9 2.0 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.6 EGC40440.1 - 0.37 10.5 1.5 0.69 9.7 1.5 1.4 1 0 0 1 1 1 0 Zinc knuckle Endotoxin_N PF03945.14 EGC40441.1 - 3.5e-06 26.9 2.4 9.9e-06 25.4 0.1 2.4 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain DUF4143 PF13635.6 EGC40441.1 - 0.05 13.8 0.1 0.11 12.6 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4143) DUF5053 PF16476.5 EGC40441.1 - 0.083 12.6 0.4 0.31 10.7 0.4 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF5053) COQ7 PF03232.13 EGC40441.1 - 0.095 12.5 0.6 0.3 10.8 0.6 1.8 2 0 0 2 2 2 0 Ubiquinone biosynthesis protein COQ7 zf-C3HC4_3 PF13920.6 EGC40443.1 - 4.1e-05 23.4 7.2 6.2e-05 22.8 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC40443.1 - 0.0067 16.7 9.0 0.0067 16.7 9.0 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.25 EGC40443.1 - 0.012 15.4 11.2 0.012 15.4 11.2 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) LIM PF00412.22 EGC40443.1 - 0.023 14.9 8.3 0.32 11.2 4.7 2.3 2 0 0 2 2 2 0 LIM domain zf-RING_14 PF17978.1 EGC40443.1 - 0.027 14.9 6.7 0.18 12.3 6.7 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.6 EGC40443.1 - 0.11 12.4 13.5 0.17 11.9 12.0 2.0 2 1 1 3 3 3 0 zinc-RING finger domain zf-C3HC4_2 PF13923.6 EGC40443.1 - 0.18 11.7 10.3 0.19 11.6 9.2 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.6 EGC40443.1 - 0.2 11.4 9.6 0.44 10.4 9.0 1.9 2 1 1 3 3 3 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.6 EGC40443.1 - 0.49 10.5 6.3 0.37 10.9 4.4 1.9 2 1 0 2 2 2 0 RING-type zinc-finger C1_2 PF03107.16 EGC40443.1 - 7.7 6.9 11.5 1.9 8.9 7.0 2.1 1 1 1 2 2 2 0 C1 domain Vps54 PF07928.12 EGC40444.1 - 6.6e-42 143.1 2.2 6.6e-42 143.1 2.2 2.8 4 0 0 4 4 4 1 Vps54-like protein RDM PF11002.8 EGC40444.1 - 0.31 11.1 4.5 0.39 10.7 0.5 2.8 3 0 0 3 3 3 0 RFPL defining motif (RDM) EGF_2 PF07974.13 EGC40445.1 - 0.039 14.3 11.9 0.12 12.8 11.9 1.9 1 0 0 1 1 1 0 EGF-like domain PP2C PF00481.21 EGC40446.1 - 2.3e-53 181.4 0.0 4.1e-53 180.6 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PEMT PF04191.13 EGC40447.1 - 3.3e-55 185.0 12.4 3.1e-33 114.3 2.8 2.9 2 0 0 2 2 2 2 Phospholipid methyltransferase NopRA1 PF16201.5 EGC40447.1 - 0.015 14.9 0.2 0.096 12.3 0.0 2.4 3 0 0 3 3 3 0 Nucleolar pre-ribosomal-associated protein 1 zf-TRAF PF02176.18 EGC40448.1 - 9.9e-12 45.4 16.2 4.2e-11 43.4 6.7 4.3 1 1 4 5 5 4 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.6 EGC40448.1 - 3e-08 33.4 9.5 3e-08 33.4 9.5 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC40448.1 - 4.1e-08 33.4 9.2 4.1e-08 33.4 9.2 3.6 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.25 EGC40448.1 - 2e-06 27.6 10.1 2e-06 27.6 10.1 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC40448.1 - 4.3e-06 26.7 5.8 2.2e-05 24.4 5.8 2.3 1 0 0 1 1 1 1 RING-type zinc-finger U-box PF04564.15 EGC40448.1 - 8.4e-05 22.7 0.1 0.00031 20.8 0.0 2.0 2 0 0 2 2 1 1 U-box domain zf-TRAF_2 PF15965.5 EGC40448.1 - 8.5e-05 23.0 23.9 0.0016 18.9 6.8 3.4 1 1 2 3 3 3 2 TRAF-like zinc-finger zf-C3HC4_3 PF13920.6 EGC40448.1 - 0.00011 22.0 10.4 0.00011 22.0 10.4 3.1 2 1 1 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC40448.1 - 0.0019 18.5 8.6 0.0019 18.5 8.6 4.1 2 2 0 2 2 1 1 RING-H2 zinc finger domain Prok-RING_4 PF14447.6 EGC40448.1 - 0.0099 15.7 10.0 0.0099 15.7 10.0 2.6 2 0 0 2 2 2 1 Prokaryotic RING finger family 4 zf-RING_5 PF14634.6 EGC40448.1 - 0.011 15.7 10.3 0.011 15.7 10.3 3.3 2 2 0 2 2 2 0 zinc-RING finger domain SKA1 PF07160.12 EGC40448.1 - 0.032 14.1 0.8 0.053 13.4 0.8 1.4 1 0 0 1 1 1 0 Spindle and kinetochore-associated protein 1 zf_C2HC_14 PF18574.1 EGC40448.1 - 0.15 11.9 0.2 0.15 11.9 0.2 5.2 4 1 1 5 5 4 0 C2HC Zing finger domain zf-LYAR PF08790.11 EGC40448.1 - 0.25 11.3 10.3 6.4 6.8 0.4 4.1 3 0 0 3 3 3 0 LYAR-type C2HC zinc finger Sina PF03145.16 EGC40448.1 - 2.8 7.8 23.3 0.35 10.8 6.7 3.8 1 1 2 3 3 3 0 Seven in absentia protein family zf-BED PF02892.15 EGC40448.1 - 5.6 7.1 11.7 0.1 12.6 1.9 3.1 3 0 0 3 3 3 0 BED zinc finger LMBR1 PF04791.16 EGC40449.1 - 5.4 5.8 11.7 7.2 5.4 11.7 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein EGF_2 PF07974.13 EGC40450.1 - 0.00016 22.0 20.7 0.00044 20.6 12.8 2.6 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.10 EGC40450.1 - 0.075 12.4 1.6 0.19 11.2 1.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF PF00008.27 EGC40450.1 - 0.29 11.5 9.7 1.2 9.6 9.7 2.1 1 0 0 1 1 1 0 EGF-like domain zf-CRD PF17979.1 EGC40451.1 - 0.48 10.5 3.0 1.3 9.1 3.1 1.7 1 1 0 1 1 1 0 Cysteine rich domain with multizinc binding regions ADH_zinc_N PF00107.26 EGC40452.1 - 7e-27 94.0 0.0 1.4e-26 93.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC40452.1 - 1.3e-21 78.0 0.0 3e-21 76.8 0.0 1.6 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC40452.1 - 3.7e-06 26.8 0.0 7e-06 25.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_N_2 PF16884.5 EGC40452.1 - 0.002 18.0 0.0 0.0038 17.1 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of oxidoreductase DapB_N PF01113.20 EGC40452.1 - 0.031 14.4 0.1 0.11 12.6 0.0 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.6 EGC40453.1 - 1.7e-43 148.9 0.0 2.9e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.25 EGC40453.1 - 4.4e-37 127.4 0.0 5.7e-37 127.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase DUF1776 PF08643.10 EGC40453.1 - 0.013 14.9 0.2 0.013 14.9 0.2 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) KR PF08659.10 EGC40453.1 - 0.023 14.6 0.0 0.037 13.9 0.0 1.3 1 0 0 1 1 1 0 KR domain Cas_APE2256 PF09651.10 EGC40453.1 - 0.029 14.3 0.0 0.055 13.4 0.0 1.4 1 0 0 1 1 1 0 CRISPR-associated protein (Cas_APE2256) PI3K_1B_p101 PF10486.9 EGC40453.1 - 0.32 8.7 10.3 0.18 9.6 8.1 1.6 2 0 0 2 2 2 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DNA_pol_phi PF04931.13 EGC40453.1 - 0.54 8.3 18.8 0.68 8.0 18.8 1.1 1 0 0 1 1 1 0 DNA polymerase phi CDC45 PF02724.14 EGC40453.1 - 0.6 8.3 13.1 0.63 8.3 13.1 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF4611 PF15387.6 EGC40453.1 - 1.4 9.2 14.4 3.4 8.0 14.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF4637 PF15470.6 EGC40453.1 - 2.6 7.8 15.2 4.3 7.0 15.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PBP1_TM PF14812.6 EGC40453.1 - 4.1 7.8 7.6 8.9 6.8 7.6 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pox_Ag35 PF03286.14 EGC40453.1 - 4.2 7.1 14.6 8 6.2 14.6 1.5 1 0 0 1 1 1 0 Pox virus Ag35 surface protein BSP_II PF05432.11 EGC40453.1 - 4.4 6.9 25.5 6 6.5 25.5 1.2 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) LAP1C PF05609.12 EGC40453.1 - 4.5 6.2 12.0 5.5 6.0 12.0 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) CENP-B_dimeris PF09026.10 EGC40453.1 - 7.4 7.0 15.9 15 6.0 15.9 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Nop14 PF04147.12 EGC40453.1 - 8.5 4.5 23.2 15 3.6 23.2 1.4 1 0 0 1 1 1 0 Nop14-like family FNIP PF05725.12 EGC40454.1 - 2.6e-43 145.9 36.9 7.7e-15 54.8 0.3 8.3 6 2 2 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 EGC40454.1 - 0.0069 16.3 2.5 0.21 11.5 0.2 2.7 1 1 2 3 3 3 3 BspA type Leucine rich repeat region (6 copies) Amidinotransf PF02274.17 EGC40455.1 - 5.9e-65 219.6 2.3 1.7e-51 175.3 0.1 3.7 3 1 0 3 3 3 3 Amidinotransferase PAD_porph PF04371.15 EGC40455.1 - 0.029 13.7 0.5 0.26 10.5 0.5 2.3 1 1 0 1 1 1 0 Porphyromonas-type peptidyl-arginine deiminase CBS PF00571.28 EGC40456.1 - 2.1e-25 88.9 4.1 1.5e-07 31.8 0.1 4.3 4 0 0 4 4 4 4 CBS domain Methyltransf_11 PF08241.12 EGC40457.1 - 1.1e-19 70.9 0.0 2e-19 70.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC40457.1 - 2.6e-17 63.3 0.0 4.7e-17 62.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC40457.1 - 3.6e-16 59.3 0.1 6.1e-16 58.6 0.1 1.5 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC40457.1 - 1.2e-15 57.8 0.0 1.4e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC40457.1 - 1.4e-14 54.6 0.0 2.6e-14 53.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.11 EGC40457.1 - 1.6e-07 30.6 0.0 2.9e-07 29.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.18 EGC40457.1 - 1.6e-06 27.6 0.0 2e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.20 EGC40457.1 - 0.00017 20.9 0.0 0.00025 20.4 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.13 EGC40457.1 - 0.0012 18.4 0.0 0.0017 17.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Pox_MCEL PF03291.16 EGC40457.1 - 0.0013 18.0 0.1 0.0032 16.6 0.1 1.5 1 1 0 1 1 1 1 mRNA capping enzyme NodS PF05401.11 EGC40457.1 - 0.0014 18.3 0.0 0.0025 17.4 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.14 EGC40457.1 - 0.0044 16.6 0.0 0.017 14.7 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase small domain WWE PF02825.20 EGC40457.1 - 0.14 12.8 0.0 0.31 11.7 0.0 1.6 1 0 0 1 1 1 0 WWE domain Endotoxin_N PF03945.14 EGC40459.1 - 4e-05 23.4 0.1 6.7e-05 22.7 0.1 1.4 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain KR PF08659.10 EGC40460.1 - 1.1e-07 32.0 0.0 1.8e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_25 PF13649.6 EGC40460.1 - 0.012 16.3 0.0 0.18 12.5 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.12 EGC40460.1 - 0.032 14.9 0.0 0.17 12.5 0.0 2.1 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.6 EGC40460.1 - 0.049 13.4 6.3 0.024 14.4 1.0 2.4 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.6 EGC40460.1 - 0.076 12.8 0.0 0.23 11.3 0.0 1.7 2 0 0 2 2 2 0 Methyltransferase domain ColG_sub PF18496.1 EGC40460.1 - 0.72 10.0 5.7 0.14 12.3 1.8 1.8 2 0 0 2 2 2 0 Collagenase G catalytic helper subdomain Dicty_CTDC PF00526.18 EGC40461.1 - 3.9e-23 81.0 65.8 8.8e-09 35.1 13.6 10.4 11 0 0 11 11 11 5 Dictyostelium (slime mold) repeat DNA_pol_A_exo1 PF01612.20 EGC40462.1 - 1.2e-18 67.5 0.0 7.2e-18 64.9 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease IBN_N PF03810.19 EGC40462.1 - 0.081 12.8 2.3 0.71 9.8 0.1 3.0 2 0 0 2 2 2 0 Importin-beta N-terminal domain eIF-1a PF01176.19 EGC40463.1 - 1.2e-20 73.0 0.0 1.8e-20 72.5 0.0 1.2 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Peptidase_M24 PF00557.24 EGC40464.1 - 2.4e-52 177.7 0.0 2.9e-52 177.4 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-C6H2 PF15801.5 EGC40464.1 - 1.7e-16 60.3 7.3 3.7e-16 59.1 7.3 1.6 1 0 0 1 1 1 1 zf-MYND-like zinc finger, mRNA-binding zf-MYND PF01753.18 EGC40464.1 - 0.0022 18.0 3.3 0.0044 17.1 3.3 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.16 EGC40464.1 - 0.093 12.6 5.8 0.29 11.0 5.8 1.9 1 0 0 1 1 1 0 HIT zinc finger SpoIIID PF12116.8 EGC40465.1 - 0.067 13.3 1.8 0.23 11.6 1.8 1.9 1 0 0 1 1 1 0 Stage III sporulation protein D Pyr_excise PF03013.14 EGC40466.1 - 0.026 14.5 0.6 0.026 14.5 0.6 2.5 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase Inhibitor_I24 PF10465.9 EGC40466.1 - 0.027 14.4 0.4 10 6.1 0.0 3.1 3 0 0 3 3 3 0 PinA peptidase inhibitor YoaP PF14268.6 EGC40466.1 - 0.22 11.1 5.6 16 5.1 0.5 3.9 3 0 0 3 3 3 0 YoaP-like EFG_II PF14492.6 EGC40467.1 - 0.2 11.8 0.1 0.32 11.1 0.1 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II EGF_2 PF07974.13 EGC40468.1 - 0.00029 21.2 21.8 0.00039 20.7 12.3 2.6 2 0 0 2 2 2 2 EGF-like domain DUF1905 PF08922.11 EGC40468.1 - 0.045 13.8 0.0 17 5.6 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1905) EGF_alliinase PF04863.13 EGC40468.1 - 1.4 9.4 5.6 4 7.9 5.6 1.8 1 0 0 1 1 1 0 Alliinase EGF-like domain SPOC PF07744.13 EGC40469.1 - 0.003 17.5 0.5 0.012 15.5 0.1 2.1 2 0 0 2 2 2 1 SPOC domain COMMD1_N PF17221.3 EGC40469.1 - 0.097 13.0 0.0 0.47 10.8 0.0 2.2 2 0 0 2 2 2 0 COMMD1 N-terminal domain FRB_dom PF08771.11 EGC40472.1 - 0.26 11.7 2.7 0.99 9.9 0.1 3.2 3 0 0 3 3 3 0 FKBP12-rapamycin binding domain PCI PF01399.27 EGC40472.1 - 1.2 9.6 7.0 0.32 11.5 1.5 3.0 3 0 0 3 3 3 0 PCI domain Pre-PUA PF17832.1 EGC40473.1 - 0.051 14.3 0.6 0.076 13.7 0.3 1.5 1 1 1 2 2 2 0 Pre-PUA-like domain SapB_2 PF03489.17 EGC40475.1 - 5.6e-17 61.5 14.8 9.9e-11 41.6 2.6 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.15 EGC40475.1 - 1e-12 47.8 14.7 5.4e-10 39.1 1.2 3.8 4 1 0 4 4 4 2 Saposin-like type B, region 1 zf-H2C2_2 PF13465.6 EGC40475.1 - 0.23 12.0 8.2 0.23 12.0 4.6 2.8 2 0 0 2 2 2 0 Zinc-finger double domain RNA_POL_M_15KD PF02150.16 EGC40475.1 - 0.47 10.4 4.5 1.6 8.7 0.1 3.1 3 0 0 3 3 3 0 RNA polymerases M/15 Kd subunit Aminotran_1_2 PF00155.21 EGC40476.1 - 2e-51 175.3 0.0 2.5e-51 175.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.21 EGC40476.1 - 0.027 13.8 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Beta-eliminating lyase FNIP PF05725.12 EGC40477.1 - 6.9e-83 272.6 81.1 5e-13 49.0 0.8 12.6 9 2 3 13 13 13 12 FNIP Repeat Pkinase PF00069.25 EGC40477.1 - 1.7e-50 171.9 5.2 1e-49 169.3 5.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.17 EGC40477.1 - 3.6e-29 101.8 1.3 9.8e-29 100.4 0.8 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase_fungal PF17667.1 EGC40477.1 - 0.0011 17.8 1.6 0.0013 17.6 0.3 1.7 2 0 0 2 2 2 1 Fungal protein kinase APH PF01636.23 EGC40477.1 - 0.08 12.9 0.0 0.37 10.7 0.1 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.6 EGC40478.1 - 3.2e-08 33.3 8.2 3.2e-08 33.3 8.2 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC40478.1 - 3.4e-07 30.5 8.8 3.4e-07 30.5 8.8 3.4 2 1 0 2 2 1 1 Ring finger domain zf-C3HC4 PF00097.25 EGC40478.1 - 1.3e-06 28.2 8.1 1.3e-06 28.2 8.1 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.6 EGC40478.1 - 4e-06 26.7 9.3 4e-06 26.7 9.3 2.6 3 0 0 3 3 2 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC40478.1 - 4.4e-06 26.7 9.9 4.4e-06 26.7 9.9 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_3 PF13920.6 EGC40478.1 - 1.6e-05 24.6 4.4 1.6e-05 24.6 4.4 3.1 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.15 EGC40478.1 - 2.1e-05 24.6 0.0 4.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-TRAF_2 PF15965.5 EGC40478.1 - 3.4e-05 24.2 17.4 0.0075 16.7 7.5 3.0 1 1 1 2 2 2 2 TRAF-like zinc-finger zf-rbx1 PF12678.7 EGC40478.1 - 0.00049 20.3 4.8 0.00049 20.3 4.8 3.4 2 1 2 4 4 4 1 RING-H2 zinc finger domain Sina PF03145.16 EGC40478.1 - 0.00081 19.4 12.0 0.026 14.5 0.3 2.5 1 1 0 2 2 2 2 Seven in absentia protein family zf-RING_6 PF14835.6 EGC40478.1 - 0.0018 18.1 6.0 0.002 18.0 3.5 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.6 EGC40478.1 - 0.0054 16.6 3.4 0.0054 16.6 3.4 3.6 2 2 1 3 3 3 2 Prokaryotic RING finger family 4 zf-Nse PF11789.8 EGC40478.1 - 0.0061 16.3 3.4 0.0061 16.3 3.4 2.9 3 1 0 3 3 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_5 PF14634.6 EGC40478.1 - 0.011 15.7 7.4 0.011 15.7 7.4 3.5 2 2 1 3 3 3 0 zinc-RING finger domain SurA_N_2 PF13623.6 EGC40478.1 - 0.035 14.0 0.1 0.17 11.8 0.0 1.9 2 0 0 2 2 2 0 SurA N-terminal domain zf-TRAF PF02176.18 EGC40478.1 - 0.15 12.7 27.1 0.068 13.9 7.3 4.3 2 2 2 4 4 4 0 TRAF-type zinc finger zf-RING_4 PF14570.6 EGC40478.1 - 0.88 9.4 19.2 0.047 13.5 7.4 3.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain DZR PF12773.7 EGC40478.1 - 3.1 7.9 13.0 1.9 8.6 5.0 3.4 2 1 1 3 3 3 0 Double zinc ribbon zf-TRAF PF02176.18 EGC40479.1 - 1.2e-14 54.7 31.3 2.2e-07 31.5 8.5 4.7 4 1 1 5 5 5 3 TRAF-type zinc finger Sina PF03145.16 EGC40479.1 - 4.2e-06 26.9 22.0 0.0056 16.7 0.5 3.4 1 1 2 3 3 3 3 Seven in absentia protein family zf-RING_UBOX PF13445.6 EGC40479.1 - 5.2e-06 26.4 7.3 1.1e-05 25.3 5.0 2.9 1 1 1 2 2 2 1 RING-type zinc-finger zf-TRAF_2 PF15965.5 EGC40479.1 - 1.1e-05 25.8 28.4 0.0018 18.7 5.8 4.4 2 1 2 4 4 4 3 TRAF-like zinc-finger zf-RING_2 PF13639.6 EGC40479.1 - 2.8e-05 24.3 11.5 2.8e-05 24.3 11.5 3.7 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EGC40479.1 - 9.2e-05 22.2 14.0 9.2e-05 22.2 14.0 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC40479.1 - 0.00019 21.2 10.3 0.00019 21.2 10.3 3.4 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC40479.1 - 0.00061 19.6 13.3 0.00061 19.6 13.3 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.6 EGC40479.1 - 0.0027 17.8 9.3 0.0027 17.8 9.3 3.7 3 2 1 4 4 3 1 zinc finger of C3HC4-type, RING U-box PF04564.15 EGC40479.1 - 0.0038 17.4 0.1 0.018 15.2 0.1 2.1 1 1 0 1 1 1 1 U-box domain zf_C2HC_14 PF18574.1 EGC40479.1 - 0.013 15.3 7.6 0.42 10.4 0.0 5.1 5 0 0 5 5 5 0 C2HC Zing finger domain FERM_F1 PF18379.1 EGC40479.1 - 0.082 12.9 0.9 7.9 6.6 0.0 2.6 2 0 0 2 2 2 0 FERM F1 ubiquitin-like domain FNIP PF05725.12 EGC40480.1 - 2.6e-54 181.1 61.0 1.7e-13 50.5 2.0 10.2 3 2 9 13 13 13 13 FNIP Repeat DUF1769 PF08588.10 EGC40480.1 - 0.014 15.5 2.7 1.1 9.5 0.0 3.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1769) Ribosomal_S4e PF00900.20 EGC40481.1 - 2.7e-33 113.7 0.1 8.7e-33 112.1 0.1 1.8 2 0 0 2 2 2 1 Ribosomal family S4e 40S_S4_C PF16121.5 EGC40481.1 - 1.5e-21 75.7 0.1 2.5e-21 75.1 0.1 1.3 1 0 0 1 1 1 1 40S ribosomal protein S4 C-terminus RS4NT PF08071.12 EGC40481.1 - 4.3e-20 71.5 8.3 1.8e-19 69.6 8.6 1.9 2 0 0 2 2 2 1 RS4NT (NUC023) domain S4 PF01479.25 EGC40481.1 - 2.2e-09 36.8 0.0 4.2e-09 36.0 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.29 EGC40481.1 - 0.016 15.2 3.7 0.032 14.2 0.0 3.2 4 0 0 4 4 4 0 KOW motif PspA_IM30 PF04012.12 EGC40482.1 - 0.044 13.3 10.8 0.066 12.8 10.8 1.4 1 1 0 1 1 1 0 PspA/IM30 family dsDNA_bind PF01984.20 EGC40482.1 - 0.22 11.8 12.8 5.5 7.3 7.1 3.2 3 0 0 3 3 3 0 Double-stranded DNA-binding domain RRM_5 PF13893.6 EGC40483.1 - 5.4e-39 132.6 0.7 1.5e-24 85.9 0.0 4.2 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.22 EGC40483.1 - 2.1e-37 126.8 0.0 2.4e-09 36.9 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_8 PF11835.8 EGC40483.1 - 3.2e-11 43.3 0.0 4.6e-10 39.6 0.0 2.2 2 0 0 2 2 2 1 RRM-like domain RRM_occluded PF16842.5 EGC40483.1 - 2.2e-09 37.0 0.1 0.098 12.5 0.1 4.2 4 0 0 4 4 4 3 Occluded RNA-recognition motif Limkain-b1 PF11608.8 EGC40483.1 - 0.00042 20.3 0.0 0.95 9.6 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 RRM_7 PF16367.5 EGC40483.1 - 0.025 14.7 0.0 6.3 7.0 0.0 3.3 3 0 0 3 3 3 0 RNA recognition motif Phage_min_cap2 PF06152.11 EGC40483.1 - 0.05 12.5 0.1 0.083 11.8 0.1 1.2 1 0 0 1 1 1 0 Phage minor capsid protein 2 DUF3568 PF12092.8 EGC40484.1 - 0.063 13.4 0.4 0.17 12.0 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Nucleoside_tran PF01733.18 EGC40485.1 - 0.57 9.5 4.1 0.56 9.5 3.4 1.4 1 1 0 1 1 1 0 Nucleoside transporter LacI PF00356.21 EGC40485.1 - 0.72 9.7 0.0 0.72 9.7 0.0 3.4 3 1 0 3 3 3 0 Bacterial regulatory proteins, lacI family FNIP PF05725.12 EGC40486.1 - 3.3e-67 222.4 32.1 1e-11 44.8 0.0 8.2 4 1 7 11 11 11 10 FNIP Repeat FBD PF08387.10 EGC40486.1 - 0.045 13.6 0.1 2.7 8.0 0.0 2.8 2 0 0 2 2 2 0 FBD Mannosidase_ig PF17786.1 EGC40486.1 - 0.12 12.9 0.0 0.23 12.1 0.0 1.4 1 0 0 1 1 1 0 Mannosidase Ig/CBM-like domain Secretin_N_2 PF07655.13 EGC40487.1 - 0.16 12.5 16.7 0.25 11.9 16.7 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1700 PF08006.11 EGC40487.1 - 0.32 10.5 4.5 0.46 10.0 4.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) CH PF00307.31 EGC40489.1 - 7.8e-35 119.4 10.5 1.1e-20 73.8 0.8 3.1 4 0 0 4 4 4 2 Calponin homology (CH) domain Hemocyanin_N PF03722.14 EGC40489.1 - 2.9 8.4 8.2 1.6 9.3 4.2 2.5 2 1 0 2 2 2 0 Hemocyanin, all-alpha domain SecD-TM1 PF13721.6 EGC40489.1 - 9.3 6.8 8.7 15 6.1 0.4 3.6 4 0 0 4 4 4 0 SecD export protein N-terminal TM region LRR_6 PF13516.6 EGC40490.1 - 6.3e-33 110.0 45.4 0.00029 20.7 0.0 13.9 13 0 0 13 13 13 12 Leucine Rich repeat F-box-like PF12937.7 EGC40490.1 - 0.0011 18.7 0.6 0.0041 17.0 0.1 2.1 2 0 0 2 2 2 1 F-box-like CBM_20 PF00686.19 EGC40491.1 - 5.5e-15 55.1 5.7 5.4e-08 32.6 0.2 4.1 3 0 0 3 3 3 3 Starch binding domain Podoplanin PF05808.11 EGC40491.1 - 0.00029 21.0 0.4 0.00065 19.8 0.4 1.5 1 0 0 1 1 1 1 Podoplanin TMEM154 PF15102.6 EGC40491.1 - 8.7 6.2 7.8 4.1 7.3 0.3 3.2 3 0 0 3 3 3 0 TMEM154 protein family zf-CCHC PF00098.23 EGC40492.1 - 7.5e-07 29.0 3.2 1.4e-06 28.1 3.2 1.4 1 0 0 1 1 1 1 Zinc knuckle DnaJ PF00226.31 EGC40493.1 - 1.2e-19 70.2 0.5 2.1e-19 69.4 0.5 1.5 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.18 EGC40493.1 - 2.8e-10 40.1 12.7 3.9e-10 39.6 12.7 1.2 1 0 0 1 1 1 1 MYND finger Chromo PF00385.24 EGC40495.1 - 6.8e-13 48.3 1.6 1.9e-12 46.9 1.6 1.9 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain DUF1869 PF08956.10 EGC40495.1 - 2 8.4 4.1 37 4.3 0.1 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1869) PSI PF01437.25 EGC40496.1 - 0.055 14.0 21.3 0.67 10.5 0.3 3.1 2 1 1 3 3 3 0 Plexin repeat Rad60-SLD PF11976.8 EGC40497.1 - 7.5e-21 73.8 0.2 9.1e-21 73.5 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.23 EGC40497.1 - 2e-10 40.2 0.2 2.5e-10 40.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin family IBR PF01485.21 EGC40498.1 - 8.7e-10 38.7 36.4 1.8e-08 34.5 12.9 4.0 3 1 0 3 3 3 2 IBR domain, a half RING-finger domain zf-RING_UBOX PF13445.6 EGC40498.1 - 3.4e-05 23.8 6.1 3.4e-05 23.8 6.1 3.6 3 0 0 3 3 3 1 RING-type zinc-finger zf-RING_2 PF13639.6 EGC40498.1 - 0.0001 22.6 9.2 0.0001 22.6 9.2 4.1 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.25 EGC40498.1 - 0.00012 21.9 6.5 0.00012 21.9 6.5 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.6 EGC40498.1 - 0.002 18.0 3.8 0.002 18.0 3.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Transpos_assoc PF13963.6 EGC40498.1 - 0.82 10.0 9.3 1.5 9.2 2.6 3.5 1 1 1 2 2 2 0 Transposase-associated domain PP-binding PF00550.25 EGC40501.1 - 1.8e-06 28.2 0.2 2.5e-06 27.7 0.2 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF2951 PF11166.8 EGC40501.1 - 0.0032 17.7 2.3 0.0042 17.3 1.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF2951) FNIP PF05725.12 EGC40502.1 - 8.7e-17 61.0 35.3 8.2e-06 25.9 2.5 7.0 5 2 2 7 7 7 6 FNIP Repeat LRR_5 PF13306.6 EGC40502.1 - 0.016 15.2 4.3 0.016 15.2 4.3 3.3 1 1 2 3 3 3 0 BspA type Leucine rich repeat region (6 copies) Xol-1_GHMP-like PF09109.10 EGC40502.1 - 0.046 13.6 0.1 5.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Switch protein XOL-1, GHMP-like 7TM_GPCR_Sru PF10322.9 EGC40503.1 - 0.045 13.1 0.2 0.06 12.7 0.2 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru Pyridoxal_deC PF00282.19 EGC40506.1 - 1.1e-77 261.3 0.0 1.4e-77 261.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain TFIIA PF03153.13 EGC40508.1 - 0.0047 17.0 43.8 0.0073 16.3 43.8 1.3 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit Dapper PF15268.6 EGC40508.1 - 9.7 4.9 26.9 14 4.4 26.9 1.3 1 0 0 1 1 1 0 Dapper Malic_M PF03949.15 EGC40509.1 - 6.6e-102 340.2 0.0 8.7e-102 339.8 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.19 EGC40509.1 - 7.5e-70 234.4 0.0 3.6e-69 232.2 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain TIG PF01833.24 EGC40510.1 - 1.8e-17 63.2 68.9 1.1e-06 28.6 2.6 8.3 8 0 0 8 8 8 7 IPT/TIG domain EGF_2 PF07974.13 EGC40510.1 - 0.02 15.2 12.0 0.051 14.0 12.0 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.24 EGC40510.1 - 0.11 12.6 8.1 0.26 11.4 8.1 1.6 1 0 0 1 1 1 0 Laminin EGF domain EGF_Tenascin PF18720.1 EGC40510.1 - 0.39 10.8 8.5 0.87 9.7 8.5 1.6 1 0 0 1 1 1 0 Tenascin EGF domain Methyltransf_11 PF08241.12 EGC40512.1 - 2.7e-19 69.6 0.0 4.9e-19 68.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC40512.1 - 2e-16 60.5 0.0 3.9e-16 59.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC40512.1 - 7.3e-12 45.3 0.0 1e-11 44.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC40512.1 - 1.6e-11 44.8 0.0 2.7e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.6 EGC40512.1 - 6.7e-10 39.0 0.0 1.2e-09 38.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC40512.1 - 1.3e-08 34.5 0.0 1.8e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC40512.1 - 1.5e-05 24.6 0.0 4.1e-05 23.2 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_8 PF05148.15 EGC40512.1 - 0.00025 21.0 0.0 0.06 13.2 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase RrnaAD PF00398.20 EGC40512.1 - 0.00026 20.2 0.1 0.00053 19.1 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.12 EGC40512.1 - 0.0003 20.4 0.0 0.00051 19.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_9 PF08003.11 EGC40512.1 - 0.0015 17.5 0.0 0.0024 16.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) FtsJ PF01728.19 EGC40512.1 - 0.002 18.3 0.0 0.0039 17.3 0.0 1.6 1 1 0 1 1 1 1 FtsJ-like methyltransferase tRNA_U5-meth_tr PF05958.11 EGC40512.1 - 0.0023 17.0 0.0 0.0044 16.1 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DREV PF05219.12 EGC40512.1 - 0.0024 17.0 0.0 0.012 14.7 0.0 2.1 2 1 0 2 2 2 1 DREV methyltransferase Methyltransf_32 PF13679.6 EGC40512.1 - 0.0047 16.9 0.0 0.0064 16.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.19 EGC40512.1 - 0.0069 16.2 0.0 0.018 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) NodS PF05401.11 EGC40512.1 - 0.027 14.1 0.0 0.042 13.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_15 PF09445.10 EGC40512.1 - 0.061 12.9 0.0 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Dickkopf_N PF04706.12 EGC40513.1 - 3e-05 24.4 13.3 3e-05 24.4 13.3 6.1 3 2 3 6 6 6 3 Dickkopf N-terminal cysteine-rich region TPR_1 PF00515.28 EGC40514.1 - 1.1e-46 154.8 6.6 9.8e-09 34.7 0.2 9.6 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.17 EGC40514.1 - 1e-36 122.1 2.3 4.9e-07 29.4 0.1 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_11 PF13414.6 EGC40514.1 - 1.7e-27 94.8 5.2 2e-05 24.1 0.0 8.0 7 1 1 8 8 8 6 TPR repeat TPR_8 PF13181.6 EGC40514.1 - 1.1e-23 81.4 1.8 9.1e-06 25.5 0.1 8.4 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.6 EGC40514.1 - 2.3e-19 68.3 14.5 0.00055 20.1 0.2 10.0 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.6 EGC40514.1 - 1.4e-14 54.1 3.8 0.012 15.8 0.1 6.0 4 1 3 7 7 7 5 Tetratricopeptide repeat TPR_16 PF13432.6 EGC40514.1 - 1.9e-14 54.0 0.0 0.00036 21.1 0.0 5.0 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_9 PF13371.6 EGC40514.1 - 2.5e-13 50.0 0.0 0.0031 17.6 0.0 5.9 5 2 1 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.6 EGC40514.1 - 4.8e-11 42.6 0.8 0.041 14.5 0.0 7.2 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_14 PF13428.6 EGC40514.1 - 3.9e-09 36.6 0.0 2.3 9.2 0.0 7.4 5 2 3 8 8 7 1 Tetratricopeptide repeat TPR_7 PF13176.6 EGC40514.1 - 5.2e-09 35.5 0.1 1.2 9.3 0.0 5.5 6 0 0 6 6 6 2 Tetratricopeptide repeat ANAPC3 PF12895.7 EGC40514.1 - 1.9e-06 28.0 8.1 0.03 14.5 0.1 4.9 3 1 1 5 5 5 2 Anaphase-promoting complex, cyclosome, subunit 3 Fis1_TPR_C PF14853.6 EGC40514.1 - 4.9e-06 26.5 6.4 0.064 13.3 0.3 4.3 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.6 EGC40514.1 - 8.2e-06 26.3 0.0 2.6 8.6 0.0 5.9 6 1 1 7 7 7 1 Tetratricopeptide repeat TPR_10 PF13374.6 EGC40514.1 - 4e-05 23.3 0.5 0.23 11.4 0.0 4.9 6 0 0 6 6 6 1 Tetratricopeptide repeat MIT PF04212.18 EGC40514.1 - 0.0033 17.5 6.0 0.23 11.5 0.2 5.1 6 0 0 6 6 6 1 MIT (microtubule interacting and transport) domain SRP_TPR_like PF17004.5 EGC40514.1 - 0.0082 16.2 5.5 0.23 11.5 0.2 3.8 4 0 0 4 4 4 1 Putative TPR-like repeat DUF1697 PF08002.11 EGC40514.1 - 0.017 15.6 0.2 0.056 13.9 0.2 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1697) Aida_N PF08910.10 EGC40514.1 - 0.17 12.3 1.3 40 4.7 0.0 3.8 3 0 0 3 3 3 0 Aida N-terminus ADH_zinc_N PF00107.26 EGC40515.1 - 1.2e-08 35.0 0.2 3.5e-08 33.5 0.1 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.6 EGC40515.1 - 0.0014 19.6 0.0 0.0031 18.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Hydrolase_3 PF08282.12 EGC40515.1 - 0.015 15.1 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase Yae1_N PF09811.9 EGC40516.1 - 8.2e-10 38.2 2.8 8.2e-10 38.2 2.8 1.5 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF5405 PF17399.2 EGC40516.1 - 0.052 13.8 0.0 0.12 12.7 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF5405) Ndc1_Nup PF09531.10 EGC40517.1 - 0.89 8.2 4.7 0.96 8.1 4.7 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4014 PF13198.6 EGC40517.1 - 1.5 9.3 5.3 0.4 11.1 0.7 2.1 1 1 2 3 3 3 0 Protein of unknown function (DUF4014) OppC_N PF12911.7 EGC40517.1 - 2.6 8.1 6.5 3 7.9 0.2 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ras PF00071.22 EGC40518.1 - 1.8e-13 50.4 0.8 5.1e-13 48.9 0.8 1.7 1 1 0 1 1 1 1 Ras family Roc PF08477.13 EGC40518.1 - 0.0018 18.4 0.3 0.0038 17.4 0.3 1.5 1 0 0 1 1 1 1 Ras of Complex, Roc, domain of DAPkinase EphA2_TM PF14575.6 EGC40519.1 - 0.03 15.2 0.3 0.059 14.2 0.3 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain YbbR PF07949.12 EGC40519.1 - 0.15 12.5 4.7 9 6.7 1.1 3.1 2 0 0 2 2 2 0 YbbR-like protein DUF3060 PF11259.8 EGC40519.1 - 0.31 10.8 7.8 0.11 12.3 2.4 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3060) STE3 PF02076.15 EGC40519.1 - 0.32 10.2 3.6 0.32 10.2 2.0 1.8 2 0 0 2 2 2 0 Pheromone A receptor FNIP PF05725.12 EGC40520.1 - 5.6e-56 186.5 35.4 8.3e-12 45.1 0.4 8.5 7 2 1 8 8 8 8 FNIP Repeat LRR_5 PF13306.6 EGC40520.1 - 0.0047 16.9 0.2 0.91 9.5 0.0 3.3 2 1 1 3 3 3 2 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC40521.1 - 4.4e-07 30.0 6.8 5.5e-06 26.5 1.0 3.6 3 1 1 4 4 4 2 FNIP Repeat zf-B_box PF00643.24 EGC40521.1 - 7.1e-07 29.3 4.1 1.4e-06 28.3 4.1 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40521.1 - 0.0017 18.4 1.9 0.0044 17.1 1.9 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) CortBP2 PF09727.9 EGC40521.1 - 0.0039 17.1 10.9 0.0061 16.5 10.9 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 DUF3086 PF11285.8 EGC40521.1 - 0.035 13.2 6.3 0.051 12.7 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) zf-TFIIIC PF12660.7 EGC40521.1 - 4 7.5 7.4 0.31 11.0 1.2 2.2 2 1 0 2 2 2 0 Putative zinc-finger of transcription factor IIIC complex zf-B_box PF00643.24 EGC40522.1 - 5.9e-07 29.5 3.8 1e-06 28.8 3.8 1.3 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40522.1 - 0.01 16.0 0.9 0.019 15.1 0.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Gemini_AL1_M PF08283.11 EGC40522.1 - 0.1 12.7 1.5 0.22 11.6 1.3 1.7 1 1 1 2 2 2 0 Geminivirus rep protein central domain FNIP PF05725.12 EGC40523.1 - 7.1e-13 48.5 19.6 5.4e-06 26.5 0.3 4.9 4 1 2 6 6 6 5 FNIP Repeat Ribosomal_L13 PF00572.18 EGC40524.1 - 6.1e-49 165.4 0.9 1.1e-48 164.7 0.9 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 DUF5634 PF18681.1 EGC40524.1 - 0.049 14.0 0.1 0.13 12.6 0.1 1.8 1 0 0 1 1 1 0 Family of unknown function (DUF5634) DUF2746 PF10874.8 EGC40524.1 - 0.087 13.3 0.0 0.34 11.4 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2746) Complex1_49kDa PF00346.19 EGC40524.1 - 0.097 11.8 0.1 0.18 10.9 0.1 1.4 1 0 0 1 1 1 0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit TPR_17 PF13431.6 EGC40525.1 - 1.6e-36 122.0 20.8 4.5e-06 26.7 0.0 9.3 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_11 PF13414.6 EGC40525.1 - 2e-10 40.2 13.1 0.051 13.3 0.1 6.4 7 0 0 7 7 7 4 TPR repeat SUKH_6 PF14568.6 EGC40525.1 - 0.063 13.7 5.8 0.3 11.5 5.8 2.2 1 0 0 1 1 1 0 SMI1-KNR4 cell-wall EGF_2 PF07974.13 EGC40527.1 - 3.5e-05 24.1 19.9 0.0003 21.1 12.1 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGC40527.1 - 0.0019 18.2 6.0 0.0019 18.2 6.0 2.1 3 0 0 3 3 3 1 Tenascin EGF domain EGF PF00008.27 EGC40527.1 - 0.51 10.7 9.6 1.8 8.9 9.6 2.0 1 0 0 1 1 1 0 EGF-like domain PMP1_2 PF08114.11 EGC40527.1 - 0.93 9.3 3.0 2.5 7.9 3.0 1.7 1 0 0 1 1 1 0 ATPase proteolipid family SKG6 PF08693.10 EGC40527.1 - 6.7 6.2 12.0 0.013 14.9 1.9 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain BILBO1_N PF18281.1 EGC40528.1 - 0.0011 19.4 0.4 0.0075 16.7 0.2 2.4 1 1 1 2 2 2 1 BILBO1 N-terminal domain Glyco_transf_28 PF03033.20 EGC40528.1 - 0.083 12.9 0.3 0.22 11.5 0.2 1.6 1 1 1 2 2 2 0 Glycosyltransferase family 28 N-terminal domain EGF_2 PF07974.13 EGC40529.1 - 2.6e-06 27.7 18.0 0.00029 21.1 12.1 2.8 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGC40529.1 - 0.00063 19.7 6.0 0.0019 18.2 6.0 1.9 1 0 0 1 1 1 1 Tenascin EGF domain SKG6 PF08693.10 EGC40529.1 - 0.0051 16.2 2.2 0.0097 15.3 2.2 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain MFS_1 PF07690.16 EGC40530.1 - 1.6e-65 221.4 52.8 1.9e-55 188.2 25.6 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.24 EGC40530.1 - 5.2e-15 55.3 20.3 3e-10 39.5 11.8 2.5 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.20 EGC40530.1 - 4.1e-08 32.0 22.2 1.3e-05 23.7 8.6 3.4 1 1 1 2 2 2 2 Organic Anion Transporter Polypeptide (OATP) family MFS_4 PF06779.14 EGC40530.1 - 6.7e-08 32.2 7.9 2.7e-07 30.2 1.2 2.1 2 0 0 2 2 2 2 Uncharacterised MFS-type transporter YbfB MFS_2 PF13347.6 EGC40530.1 - 7.5e-08 31.3 28.3 0.00019 20.2 6.0 2.5 2 1 0 2 2 2 2 MFS/sugar transport protein MFS_1_like PF12832.7 EGC40530.1 - 3.3e-07 29.5 18.7 0.00051 19.0 13.6 2.5 1 1 1 2 2 2 2 MFS_1 like family LacY_symp PF01306.19 EGC40530.1 - 0.0039 16.0 13.0 0.0039 16.0 13.0 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter PTR2 PF00854.21 EGC40530.1 - 0.0051 15.7 23.6 0.17 10.7 0.0 3.3 3 0 0 3 3 3 2 POT family MFS_3 PF05977.13 EGC40530.1 - 0.019 13.4 23.2 0.043 12.2 2.1 3.5 2 2 1 3 3 3 0 Transmembrane secretion effector MccV PF17508.2 EGC40530.1 - 0.15 12.6 0.5 0.4 11.2 0.5 1.7 1 0 0 1 1 1 0 Microcin V bacteriocin Gly-zipper_Omp PF13488.6 EGC40530.1 - 1.4 9.0 7.2 1.6 8.8 4.8 2.4 3 0 0 3 3 3 0 Glycine zipper Orf78 PF06024.12 EGC40531.1 - 2.3e-05 24.6 0.6 2.3e-05 24.6 0.6 3.0 2 1 1 3 3 3 1 Orf78 (ac78) RIFIN PF02009.16 EGC40531.1 - 0.012 15.5 3.5 0.012 15.5 3.5 2.4 2 1 1 3 3 3 0 Rifin DUF4448 PF14610.6 EGC40531.1 - 0.02 14.7 0.8 0.041 13.6 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) LRRC37AB_C PF14914.6 EGC40531.1 - 0.086 12.7 0.4 0.086 12.7 0.4 2.6 3 0 0 3 3 3 0 LRRC37A/B like protein 1 C-terminal domain Pox_EPC_I2-L1 PF12575.8 EGC40531.1 - 0.12 12.6 0.2 0.44 10.8 0.2 2.0 1 0 0 1 1 1 0 Poxvirus entry protein complex L1 and I2 DUF4366 PF14283.6 EGC40531.1 - 0.41 10.7 9.8 0.12 12.4 2.8 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) DUF2347 PF09804.9 EGC40531.1 - 3.4 7.2 10.9 0.27 10.8 1.9 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) FNIP PF05725.12 EGC40532.1 - 2.3e-25 88.5 53.1 1.3e-09 38.1 0.5 9.7 8 0 0 8 8 8 6 FNIP Repeat PI3_PI4_kinase PF00454.27 EGC40532.1 - 6.4e-05 22.9 1.3 0.097 12.5 0.1 3.3 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase B3_4 PF03483.17 EGC40532.1 - 0.17 11.5 1.2 5.3 6.7 0.0 3.1 3 0 0 3 3 3 0 B3/4 domain LRR_6 PF13516.6 EGC40533.1 - 9.5e-14 50.2 54.3 0.022 14.8 0.0 11.5 12 0 0 12 12 12 6 Leucine Rich repeat LRR_4 PF12799.7 EGC40533.1 - 4.4e-07 30.1 45.1 0.043 14.3 7.9 7.3 6 1 1 7 7 7 4 Leucine Rich repeats (2 copies) F-box-like PF12937.7 EGC40533.1 - 0.004 17.0 0.1 0.0091 15.9 0.1 1.6 1 0 0 1 1 1 1 F-box-like YL1 PF05764.13 EGC40533.1 - 0.021 15.0 1.4 0.036 14.2 1.4 1.3 1 0 0 1 1 1 0 YL1 nuclear protein F-box_5 PF18511.1 EGC40533.1 - 0.094 12.3 0.7 2.3 7.9 0.1 2.9 3 0 0 3 3 3 0 F-box CPSF100_C PF13299.6 EGC40533.1 - 0.11 12.7 0.5 0.2 11.8 0.5 1.3 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal SRP1_TIP1 PF00660.17 EGC40533.1 - 0.12 12.5 0.2 0.33 11.1 0.2 1.7 1 0 0 1 1 1 0 Seripauperin and TIP1 family LRR_8 PF13855.6 EGC40533.1 - 3.6 7.4 38.8 2.5 7.9 8.0 7.1 6 2 1 7 7 7 0 Leucine rich repeat LRR_1 PF00560.33 EGC40533.1 - 6.4 7.7 34.3 32 5.6 0.6 9.5 11 0 0 11 11 11 0 Leucine Rich Repeat SDA1 PF05285.12 EGC40533.1 - 6.5 6.1 10.5 11 5.3 10.5 1.2 1 0 0 1 1 1 0 SDA1 LRR_8 PF13855.6 EGC40534.1 - 0.0058 16.4 6.4 0.28 11.0 0.4 4.3 2 1 1 3 3 3 2 Leucine rich repeat LRR_8 PF13855.6 EGC40535.1 - 0.011 15.5 3.4 0.12 12.1 0.5 4.0 1 1 2 3 3 3 0 Leucine rich repeat ASXH PF13919.6 EGC40535.1 - 0.9 9.5 3.5 3.7 7.6 0.6 3.0 3 0 0 3 3 3 0 Asx homology domain LRR_8 PF13855.6 EGC40536.1 - 0.0025 17.5 0.3 0.0025 17.5 0.3 4.7 3 1 2 5 5 5 2 Leucine rich repeat Arm PF00514.23 EGC40538.1 - 7.8e-15 54.3 8.1 2.4e-08 33.7 0.2 8.4 8 1 1 9 9 9 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 EGC40538.1 - 2.3e-05 24.6 4.3 0.64 10.3 0.1 4.7 5 1 1 6 6 6 3 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.13 EGC40539.1 - 7e-05 22.4 0.2 7e-05 22.4 0.2 1.5 2 0 0 2 2 2 1 Armadillo-like Daxx PF03344.15 EGC40539.1 - 0.067 13.3 1.9 0.91 9.6 0.1 2.7 3 0 0 3 3 3 0 Daxx N-terminal Rassf1C-interacting domain Med24_N PF11277.8 EGC40540.1 - 1.8e-11 42.9 0.1 1.8e-11 42.9 0.1 4.6 6 0 0 6 6 6 2 Mediator complex subunit 24 N-terminal SSP160 PF06933.11 EGC40542.1 - 0.1 10.8 16.7 0.2 9.8 16.7 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.17 EGC40542.1 - 0.76 9.8 30.0 1.6 8.7 30.0 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UQ_con PF00179.26 EGC40543.1 - 4.7e-43 146.2 0.1 7.8e-43 145.5 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.6 EGC40543.1 - 2.2e-09 37.9 0.0 1.2e-08 35.6 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD PF11976.8 EGC40543.1 - 3.1e-06 26.9 0.5 7e-06 25.8 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like VWA PF00092.28 EGC40543.1 - 1.1e-05 25.7 0.0 3.2e-05 24.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.23 EGC40543.1 - 6e-05 22.7 0.2 0.00013 21.6 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family TUG-UBL1 PF11470.8 EGC40543.1 - 9.3e-05 22.6 0.1 0.00022 21.4 0.1 1.7 1 0 0 1 1 1 1 TUG ubiquitin-like domain RWD PF05773.22 EGC40543.1 - 0.00054 20.2 0.0 0.0012 19.1 0.0 1.5 1 0 0 1 1 1 1 RWD domain Prok-E2_B PF14461.6 EGC40543.1 - 0.011 15.4 0.0 0.025 14.3 0.0 1.7 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.13 EGC40543.1 - 0.13 12.2 0.1 0.26 11.1 0.1 1.5 1 0 0 1 1 1 0 UEV domain ATF7IP_BD PF16788.5 EGC40543.1 - 7.2 6.6 8.1 0.83 9.7 3.9 1.5 2 0 0 2 2 2 0 ATF-interacting protein binding domain 7tm_3 PF00003.22 EGC40544.1 - 0.00079 19.2 3.6 0.025 14.3 3.8 2.4 1 1 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR EphA2_TM PF14575.6 EGC40544.1 - 0.00099 19.9 4.9 13 6.8 0.2 4.1 2 2 2 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF5385 PF17359.2 EGC40544.1 - 0.013 15.1 0.1 11 5.5 0.0 3.3 4 0 0 4 4 4 0 Family of unknown function (DUF5385) DUF3619 PF12279.8 EGC40544.1 - 0.017 15.4 6.1 0.15 12.4 0.3 3.3 1 1 3 4 4 4 0 Protein of unknown function (DUF3619) DUF373 PF04123.13 EGC40544.1 - 0.032 13.7 1.5 0.046 13.2 1.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) Colicin_V PF02674.16 EGC40544.1 - 0.091 12.7 7.7 0.86 9.6 0.0 3.2 2 1 1 3 3 3 0 Colicin V production protein Glyco_hydro_88 PF07470.13 EGC40544.1 - 0.14 11.2 6.8 8.2 5.4 0.1 3.5 1 1 3 4 4 4 0 Glycosyl Hydrolase Family 88 SARAF PF06682.12 EGC40544.1 - 0.15 11.7 2.8 6.3 6.3 0.0 3.3 2 1 1 3 3 3 0 SOCE-associated regulatory factor of calcium homoeostasis Oxidored_q3 PF00499.20 EGC40544.1 - 0.27 10.9 3.8 35 4.1 3.8 2.8 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF202 PF02656.15 EGC40544.1 - 0.28 11.7 13.7 9.1 6.8 0.5 4.3 1 1 1 3 3 3 0 Domain of unknown function (DUF202) O-ag_pol_Wzy PF14296.6 EGC40544.1 - 0.35 9.4 7.2 0.045 12.4 0.6 2.3 1 1 0 2 2 2 0 O-antigen polysaccharide polymerase Wzy DUF5134 PF17197.4 EGC40544.1 - 0.39 10.6 15.3 3.1 7.7 0.0 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF5134) HemX PF04375.14 EGC40544.1 - 0.46 9.7 1.8 23 4.1 0.2 3.6 1 1 4 5 5 5 0 HemX, putative uroporphyrinogen-III C-methyltransferase DUF4818 PF16089.5 EGC40544.1 - 0.83 10.1 4.3 0.41 11.1 0.3 2.5 2 2 1 3 3 3 0 Domain of unknown function (DUF4818) MARVEL PF01284.23 EGC40544.1 - 1.4 9.0 7.1 1.1e+02 2.8 7.4 3.0 1 1 1 2 2 2 0 Membrane-associating domain UCH PF00443.29 EGC40545.1 - 2.2e-36 125.7 55.4 2.2e-36 125.7 55.4 4.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.6 EGC40545.1 - 5.9e-09 36.0 0.0 5.9e-09 36.0 0.0 6.1 3 1 0 5 5 5 1 Ubiquitin carboxyl-terminal hydrolase DUF4366 PF14283.6 EGC40545.1 - 0.0059 16.7 4.5 0.0059 16.7 4.5 5.4 5 1 0 5 5 5 1 Domain of unknown function (DUF4366) DUF4428 PF14471.6 EGC40545.1 - 0.013 15.4 0.8 1.2 9.2 0.1 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4428) zf-C4_ClpX PF06689.13 EGC40545.1 - 0.017 15.0 1.4 3.3 7.7 0.1 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger Na_trans_assoc PF06512.13 EGC40545.1 - 0.032 14.5 0.0 0.032 14.5 0.0 6.2 4 2 1 5 5 5 0 Sodium ion transport-associated AI-2E_transport PF01594.16 EGC40545.1 - 1 8.5 5.2 1.3 8.1 2.7 2.1 2 0 0 2 2 2 0 AI-2E family transporter K1 PF02960.14 EGC40546.1 - 0.034 14.3 0.5 0.083 13.0 0.5 1.8 1 0 0 1 1 1 0 K1 glycoprotein DUF373 PF04123.13 EGC40546.1 - 0.052 13.0 14.7 0.23 10.9 10.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) adh_short PF00106.25 EGC40547.1 - 1.1e-37 129.4 0.0 1.3e-37 129.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.6 EGC40547.1 - 3.8e-26 92.1 0.0 4.4e-26 91.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.10 EGC40547.1 - 4e-07 30.1 0.0 5.1e-07 29.8 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.10 EGC40547.1 - 0.003 17.0 0.1 0.0054 16.1 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) FNIP PF05725.12 EGC40548.1 - 1.7e-100 329.0 44.5 6.9e-14 51.7 0.3 8.2 6 1 1 8 8 8 8 FNIP Repeat PH PF00169.29 EGC40549.1 - 2.7e-23 82.5 5.0 3.6e-23 82.1 0.2 3.2 3 0 0 3 3 3 1 PH domain PTEN_C2 PF10409.9 EGC40549.1 - 5.9e-23 81.1 0.0 1.2e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.6 EGC40549.1 - 2e-07 31.4 0.0 2e-07 31.4 0.0 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain PH_8 PF15409.6 EGC40549.1 - 7.9e-06 26.1 0.0 2.4e-05 24.5 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase PF00102.27 EGC40549.1 - 0.00035 20.2 0.0 0.00085 19.0 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.20 EGC40549.1 - 0.00035 20.4 0.0 0.00035 20.4 0.0 2.9 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.6 EGC40549.1 - 0.00052 20.0 0.0 0.001 19.1 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PH_3 PF14593.6 EGC40549.1 - 0.0031 17.6 1.1 0.012 15.7 0.1 2.4 1 1 1 2 2 2 1 PH domain PTPlike_phytase PF14566.6 EGC40549.1 - 0.084 13.0 0.1 0.4 10.8 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate FNIP PF05725.12 EGC40551.1 - 3e-115 376.2 46.0 4.1e-17 62.1 0.5 10.6 8 3 2 10 10 10 10 FNIP Repeat Peptidase_C21 PF05381.12 EGC40551.1 - 0.13 12.6 9.4 44 4.5 0.2 5.2 1 1 2 4 4 4 0 Tymovirus endopeptidase Keratin_assoc PF09775.9 EGC40551.1 - 0.21 11.2 4.1 31 4.2 0.2 4.1 2 2 0 4 4 4 0 Keratinocyte-associated protein 2 FNIP PF05725.12 EGC40552.1 - 1.2e-56 188.6 52.4 4.4e-10 39.6 0.0 11.1 4 4 5 11 11 11 10 FNIP Repeat LRR_5 PF13306.6 EGC40552.1 - 2.5e-08 33.9 9.6 2.6e-05 24.2 0.0 4.2 4 0 0 4 4 4 3 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC40553.1 - 1.8e-96 316.1 41.7 2.9e-16 59.4 0.4 8.3 4 2 5 10 10 10 10 FNIP Repeat Keratin_assoc PF09775.9 EGC40553.1 - 0.018 14.7 3.5 31 4.2 0.1 5.2 2 2 2 6 6 6 0 Keratinocyte-associated protein 2 BPD_transp_1 PF00528.22 EGC40553.1 - 1.9 8.2 6.8 2 8.1 0.4 3.7 2 2 1 3 3 3 0 Binding-protein-dependent transport system inner membrane component LRR_1 PF00560.33 EGC40553.1 - 6.8 7.7 16.6 80 4.4 0.2 7.2 6 2 0 6 6 6 0 Leucine Rich Repeat zf-HC5HC2H PF13771.6 EGC40554.1 - 0.15 12.4 2.3 0.52 10.6 2.3 1.8 1 1 0 1 1 1 0 PHD-like zinc-binding domain FNIP PF05725.12 EGC40555.1 - 9.4e-106 345.8 50.2 8.7e-16 57.8 0.5 8.3 2 1 4 10 10 10 9 FNIP Repeat Keratin_assoc PF09775.9 EGC40555.1 - 0.0055 16.4 1.7 20 4.8 0.0 6.0 2 2 5 8 8 8 2 Keratinocyte-associated protein 2 LRR_1 PF00560.33 EGC40555.1 - 5.1 8.0 9.8 2.9e+02 2.7 0.0 6.6 5 4 1 6 6 6 0 Leucine Rich Repeat FNIP PF05725.12 EGC40556.1 - 3.3e-18 65.6 19.6 2.4e-05 24.4 0.0 5.7 3 1 1 4 4 4 4 FNIP Repeat zf-B_box PF00643.24 EGC40556.1 - 0.00016 21.8 4.2 0.00031 20.8 4.2 1.5 1 0 0 1 1 1 1 B-box zinc finger FNIP PF05725.12 EGC40557.1 - 0.00059 19.9 0.6 0.0014 18.8 0.6 1.7 1 0 0 1 1 1 1 FNIP Repeat TPR_17 PF13431.6 EGC40558.1 - 0.057 13.8 1.8 0.42 11.1 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF4890 PF16231.5 EGC40558.1 - 8.9 6.8 8.8 0.36 11.3 1.5 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4890) FNIP PF05725.12 EGC40559.1 - 2.5e-63 210.0 53.8 1.4e-10 41.1 0.6 10.6 7 4 3 10 10 10 10 FNIP Repeat Maf1 PF09174.10 EGC40559.1 - 0.0028 17.8 0.1 0.0064 16.7 0.0 1.6 2 0 0 2 2 2 1 Maf1 regulator LRR_5 PF13306.6 EGC40559.1 - 0.075 13.0 8.3 0.39 10.7 0.6 4.2 2 2 1 4 4 4 0 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC40560.1 - 1.5e-58 194.7 58.8 3.5e-10 39.9 0.1 10.9 6 2 6 13 13 13 12 FNIP Repeat FNIP PF05725.12 EGC40562.1 - 1.6e-50 169.0 53.4 1.7e-10 40.9 2.9 9.1 6 3 3 9 9 9 8 FNIP Repeat LRR_2 PF07723.13 EGC40562.1 - 0.22 12.2 2.0 36 5.3 0.0 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.12 EGC40563.1 - 2e-95 312.8 87.4 1.1e-11 44.7 1.0 15.4 9 5 5 14 14 14 14 FNIP Repeat LRR_2 PF07723.13 EGC40563.1 - 0.015 16.0 1.0 76 4.2 0.0 4.5 4 0 0 4 4 4 0 Leucine Rich Repeat DUF5395 PF17373.2 EGC40563.1 - 0.029 15.0 0.0 2.6 8.7 0.0 3.2 3 0 0 3 3 3 0 Family of unknown function (DUF5395) FNIP PF05725.12 EGC40564.1 - 5.1e-89 292.2 79.7 3.4e-11 43.1 2.2 15.1 7 4 6 16 16 16 16 FNIP Repeat LRR_2 PF07723.13 EGC40564.1 - 1.3 9.8 6.9 1.1e+02 3.8 0.2 4.7 4 0 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.12 EGC40565.1 - 4.2e-71 234.9 73.5 3.1e-11 43.3 2.2 11.2 5 4 6 12 12 12 11 FNIP Repeat FNIP PF05725.12 EGC40566.1 - 8.1e-62 205.2 52.0 7.9e-13 48.4 0.0 10.4 4 2 6 11 11 11 10 FNIP Repeat FNIP PF05725.12 EGC40567.1 - 1.1e-44 150.3 69.6 1.6e-09 37.8 1.5 8.9 2 1 8 11 11 11 10 FNIP Repeat FNIP PF05725.12 EGC40568.1 - 3.1e-64 212.9 102.3 1e-08 35.2 1.9 12.2 2 2 14 16 16 16 16 FNIP Repeat FNIP PF05725.12 EGC40569.1 - 2.8e-58 193.9 79.2 1.8e-12 47.2 0.1 11.9 2 2 12 15 15 15 13 FNIP Repeat DUF538 PF04398.12 EGC40569.1 - 0.16 12.4 0.9 1.5e+02 2.9 0.0 4.2 4 1 1 5 5 5 0 Protein of unknown function, DUF538 PRK PF00485.18 EGC40571.1 - 2.4e-51 174.3 0.1 2.9e-51 174.0 0.1 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.6 EGC40571.1 - 2e-07 31.6 0.1 4.2e-07 30.6 0.1 1.5 1 1 0 1 1 1 1 AAA domain CoaE PF01121.20 EGC40571.1 - 2.3e-06 27.4 0.0 0.00074 19.2 0.0 2.1 2 0 0 2 2 2 2 Dephospho-CoA kinase Cytidylate_kin PF02224.18 EGC40571.1 - 0.00092 19.0 0.0 0.34 10.6 0.0 2.2 2 0 0 2 2 2 2 Cytidylate kinase Pox_A32 PF04665.12 EGC40571.1 - 0.0011 18.5 0.0 0.0021 17.6 0.0 1.5 1 0 0 1 1 1 1 Poxvirus A32 protein AAA_17 PF13207.6 EGC40571.1 - 0.0012 19.3 2.6 0.033 14.6 2.6 2.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.12 EGC40571.1 - 0.0015 17.8 0.0 0.0045 16.3 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin T2SSE PF00437.20 EGC40571.1 - 0.0023 17.1 0.0 0.0043 16.1 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein cobW PF02492.19 EGC40571.1 - 0.016 14.8 0.0 0.024 14.2 0.0 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.6 EGC40571.1 - 0.023 14.9 0.0 0.033 14.4 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.6 EGC40571.1 - 0.03 14.4 0.2 0.11 12.5 0.2 2.1 1 1 0 1 1 1 0 AAA domain APS_kinase PF01583.20 EGC40571.1 - 0.031 14.2 0.0 0.079 12.8 0.0 1.6 2 0 0 2 2 2 0 Adenylylsulphate kinase DUF722 PF05263.11 EGC40571.1 - 0.067 13.4 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF722) Thymidylate_kin PF02223.17 EGC40571.1 - 0.074 12.7 0.2 2 8.0 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase ATPase_2 PF01637.18 EGC40571.1 - 0.076 12.9 0.1 0.13 12.2 0.1 1.7 1 1 0 1 1 1 0 ATPase domain predominantly from Archaea DUF87 PF01935.17 EGC40571.1 - 0.086 12.9 0.2 0.24 11.5 0.2 1.9 1 1 0 1 1 1 0 Helicase HerA, central domain MeaB PF03308.16 EGC40571.1 - 0.14 11.1 0.0 0.63 9.0 0.0 1.9 2 0 0 2 2 2 0 Methylmalonyl Co-A mutase-associated GTPase MeaB NTPase_1 PF03266.15 EGC40571.1 - 0.16 11.9 0.1 0.44 10.5 0.0 1.8 2 0 0 2 2 2 0 NTPase ATP-cone PF03477.16 EGC40572.1 - 0.035 14.7 0.3 0.043 14.4 0.3 1.1 1 0 0 1 1 1 0 ATP cone domain DUF2529 PF10740.9 EGC40572.1 - 0.07 12.8 0.0 0.078 12.6 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2529) Phytochelatin_C PF09328.10 EGC40572.1 - 0.099 12.0 0.4 0.11 11.8 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1984) DUF4757 PF15949.5 EGC40572.1 - 0.62 10.5 4.8 0.76 10.2 4.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4757) Ribosomal_L12 PF00542.19 EGC40574.1 - 2.1e-16 60.0 5.7 2.1e-16 60.0 5.7 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain Ribosomal_L12_N PF16320.5 EGC40574.1 - 2.4e-07 30.3 15.4 3e-06 26.9 10.9 3.3 2 1 0 2 2 2 1 Ribosomal protein L7/L12 dimerisation domain DUF3231 PF11553.8 EGC40574.1 - 0.069 12.8 0.4 3.2 7.4 0.1 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF3231) SpoVIF PF14069.6 EGC40574.1 - 0.081 12.7 2.0 0.93 9.3 0.2 2.5 2 0 0 2 2 2 0 Stage VI sporulation protein F NUFIP1 PF10453.9 EGC40575.1 - 4.1e-14 52.2 10.2 4.1e-14 52.2 10.2 6.3 7 2 1 8 8 8 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) eIF-3_zeta PF05091.12 EGC40576.1 - 3.7e-161 537.6 6.3 4.4e-161 537.4 6.3 1.1 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) NARG2_C PF10505.9 EGC40576.1 - 5.4e-05 22.8 0.0 0.00024 20.7 0.0 2.1 2 1 0 2 2 2 1 NMDA receptor-regulated gene protein 2 C-terminus Aldo_ket_red PF00248.21 EGC40577.1 - 7.2e-05 22.1 0.1 0.00017 20.9 0.1 1.5 1 1 0 1 1 1 1 Aldo/keto reductase family BTB_2 PF02214.22 EGC40578.1 - 6.1e-14 52.1 0.4 1.6e-09 38.0 0.3 3.0 2 1 0 2 2 2 2 BTB/POZ domain DUSP PF06337.12 EGC40578.1 - 1e-10 42.1 0.1 1e-10 42.1 0.1 3.1 2 1 0 2 2 2 1 DUSP domain BTB_3 PF16017.5 EGC40578.1 - 0.02 15.0 0.1 1.6 8.9 0.0 3.2 3 0 0 3 3 3 0 BTB/POZ domain BTB PF00651.31 EGC40578.1 - 0.028 14.6 0.0 0.069 13.4 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain FNIP PF05725.12 EGC40579.1 - 9.6e-72 236.9 27.7 8.6e-13 48.2 1.7 7.0 3 3 3 7 7 7 7 FNIP Repeat LRR_5 PF13306.6 EGC40579.1 - 0.00016 21.6 0.2 0.0025 17.8 0.0 2.4 1 1 2 3 3 3 1 BspA type Leucine rich repeat region (6 copies) FNIP PF05725.12 EGC40580.1 - 2.7e-90 296.3 131.0 3.9e-05 23.7 0.0 24.4 11 2 18 31 31 31 30 FNIP Repeat zf-B_box PF00643.24 EGC40580.1 - 0.00016 21.7 6.2 0.0003 20.9 6.2 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40580.1 - 0.033 14.4 2.2 0.064 13.4 2.2 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) FNIP PF05725.12 EGC40581.1 - 2e-48 162.3 60.6 1.6e-07 31.4 0.5 10.7 4 2 10 14 14 14 14 FNIP Repeat FNIP PF05725.12 EGC40582.1 - 1.8e-34 117.7 61.0 2.1e-06 27.8 0.2 13.4 6 3 9 16 16 16 15 FNIP Repeat zf-B_box PF00643.24 EGC40582.1 - 5.9e-05 23.1 6.3 0.00011 22.3 6.3 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40582.1 - 0.21 11.8 2.1 0.42 10.8 2.1 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.24 EGC40583.1 - 7.9e-06 25.9 4.0 7.9e-06 25.9 4.0 1.6 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.20 EGC40583.1 - 0.014 15.5 2.1 0.03 14.5 1.6 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Sec23_trunk PF04811.15 EGC40583.1 - 0.02 14.5 0.2 0.035 13.7 0.2 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain Goodbye PF17109.5 EGC40583.1 - 0.03 14.8 0.4 0.1 13.0 0.0 2.0 1 1 1 2 2 2 0 fungal STAND N-terminal Goodbye domain PDZ_1 PF12812.7 EGC40583.1 - 0.51 10.4 5.0 7.6 6.6 0.2 3.3 2 1 1 3 3 3 0 PDZ-like domain zf-B_box PF00643.24 EGC40584.1 - 9.4e-06 25.7 4.1 1.5e-05 25.1 4.1 1.3 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.20 EGC40584.1 - 0.1 12.8 1.8 0.18 12.0 1.8 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) NEMP PF10225.9 EGC40584.1 - 0.21 11.2 0.0 0.27 10.9 0.0 1.2 1 0 0 1 1 1 0 NEMP family Get5_C PF18514.1 EGC40584.1 - 2.9 7.7 5.2 0.37 10.5 0.3 2.1 2 0 0 2 2 2 0 Get5 C-terminal domain LMBR1 PF04791.16 EGC40584.1 - 5 5.9 7.9 5.4 5.8 7.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein FNIP PF05725.12 EGC40585.1 - 9.3e-76 249.8 107.0 7.1e-07 29.3 0.2 18.7 8 3 3 19 19 19 18 FNIP Repeat zf-B_box PF00643.24 EGC40585.1 - 1.7e-06 28.1 3.7 2.9e-06 27.3 3.7 1.4 1 0 0 1 1 1 1 B-box zinc finger PPR_2 PF13041.6 EGC40585.1 - 0.077 13.2 0.5 33 4.8 0.1 3.9 4 0 0 4 4 4 0 PPR repeat family zf-UBR PF02207.20 EGC40585.1 - 0.2 11.9 1.3 0.38 10.9 1.3 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TAP_C PF03943.13 EGC40585.1 - 0.2 11.3 0.4 0.81 9.4 0.4 2.1 1 0 0 1 1 1 0 TAP C-terminal domain SNRNP27 PF08648.12 EGC40585.1 - 4.1 7.6 25.7 1.7e+02 2.4 0.0 10.2 13 0 0 13 13 13 0 U4/U6.U5 small nuclear ribonucleoproteins FNIP PF05725.12 EGC40586.1 - 1.6e-07 31.4 19.9 9.6e-07 28.9 1.8 4.4 3 1 1 5 5 5 3 FNIP Repeat zf-B_box PF00643.24 EGC40586.1 - 4.6e-06 26.7 5.3 9.3e-06 25.7 5.3 1.5 1 0 0 1 1 1 1 B-box zinc finger Heme_oxygenase PF01126.20 EGC40586.1 - 0.033 14.0 0.2 0.063 13.1 0.2 1.4 1 0 0 1 1 1 0 Heme oxygenase FNIP PF05725.12 EGC40587.1 - 1.6e-38 130.6 29.7 3e-11 43.3 0.6 6.4 6 0 0 6 6 6 5 FNIP Repeat FNIP PF05725.12 EGC40588.1 - 4.6e-07 29.9 0.2 1.2e-06 28.6 0.0 1.7 2 0 0 2 2 2 1 FNIP Repeat RasGAP PF00616.19 EGC40589.1 - 7.7e-27 94.4 0.1 1.5e-15 57.5 0.1 5.8 4 2 1 5 5 5 2 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.14 EGC40589.1 - 2.8e-25 88.7 0.0 1e-24 86.9 0.0 2.1 1 0 0 1 1 1 1 Protein of unknown function, DUF547 EBP50_C PF09007.11 EGC40589.1 - 0.012 16.6 0.5 0.012 16.6 0.5 8.4 5 4 3 9 9 9 0 EBP50, C-terminal RraB PF06877.11 EGC40590.1 - 0.98 10.2 5.2 0.62 10.8 1.1 2.8 2 1 0 2 2 2 0 Regulator of ribonuclease activity B UQ_con PF00179.26 EGC40591.1 - 3.7e-37 127.1 0.2 4.1e-37 127.0 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme zf-C3HC4_2 PF13923.6 EGC40592.1 - 4.3e-08 32.9 8.2 8.7e-08 31.9 8.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC40592.1 - 4.4e-08 32.9 9.4 8.4e-08 32.0 9.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.6 EGC40592.1 - 2.4e-06 27.3 8.0 4.9e-06 26.3 8.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4 PF00097.25 EGC40592.1 - 2.7e-06 27.1 11.0 6.2e-06 26.0 11.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.6 EGC40592.1 - 8e-05 22.9 9.7 0.00016 21.9 9.7 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.6 EGC40592.1 - 0.00011 22.0 9.4 0.0003 20.7 9.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.6 EGC40592.1 - 0.00036 20.5 9.0 0.00081 19.4 9.0 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.7 EGC40592.1 - 0.0015 18.8 5.0 0.0049 17.1 5.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_6 PF14835.6 EGC40592.1 - 0.018 14.9 3.0 0.037 13.9 3.0 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-ANAPC11 PF12861.7 EGC40592.1 - 0.048 13.7 3.2 0.072 13.2 1.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.6 EGC40592.1 - 0.11 12.7 8.3 0.26 11.5 8.3 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.6 EGC40592.1 - 0.57 10.0 9.4 1.4 8.7 9.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.8 EGC40592.1 - 0.71 9.7 5.7 2.5 8.0 5.7 2.0 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SUI1 PF01253.22 EGC40593.1 - 3.6e-22 78.7 0.1 5.4e-22 78.1 0.1 1.3 1 0 0 1 1 1 1 Translation initiation factor SUI1 BRCT_2 PF16589.5 EGC40594.1 - 1.4e-11 44.7 0.6 3.7e-11 43.3 0.6 1.8 1 0 0 1 1 1 1 BRCT domain, a BRCA1 C-terminus domain BRCT PF00533.26 EGC40594.1 - 6.1e-09 36.1 0.7 6.1e-09 36.1 0.7 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain WWE PF02825.20 EGC40594.1 - 0.0028 18.2 0.0 0.0073 16.9 0.0 1.8 1 0 0 1 1 1 1 WWE domain PTCB-BRCT PF12738.7 EGC40594.1 - 0.0052 16.7 0.1 0.022 14.7 0.0 2.1 2 0 0 2 2 2 1 twin BRCT domain DUF4898 PF16239.5 EGC40594.1 - 0.023 14.6 1.6 3.3 7.7 0.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4898) Synaptobrevin PF00957.21 EGC40595.1 - 3.5e-05 23.5 2.7 7.1e-05 22.5 2.7 1.5 1 0 0 1 1 1 1 Synaptobrevin ANAPC4_WD40 PF12894.7 EGC40595.1 - 0.00058 20.1 0.0 2.5 8.5 0.0 4.7 5 0 0 5 5 5 1 Anaphase-promoting complex subunit 4 WD40 domain Peptidase_S49_N PF08496.10 EGC40595.1 - 0.00062 19.9 1.4 0.00062 19.9 1.4 1.8 2 0 0 2 2 2 1 Peptidase family S49 N-terminal WD40 PF00400.32 EGC40595.1 - 0.019 15.9 0.1 75 4.4 0.0 5.6 5 0 0 5 5 5 0 WD domain, G-beta repeat FAM176 PF14851.6 EGC40595.1 - 0.31 10.7 3.2 1.1 9.0 0.7 2.4 2 0 0 2 2 2 0 FAM176 family MecA PF05389.12 EGC40595.1 - 0.37 10.4 7.4 0.1 12.2 3.3 2.1 2 0 0 2 2 2 0 Negative regulator of genetic competence (MecA) Glycos_transf_2 PF00535.26 EGC40596.1 - 2.5e-22 79.5 0.9 2.5e-22 79.5 0.9 1.9 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.9 EGC40596.1 - 2.3e-12 47.0 2.8 2.3e-12 47.0 2.8 2.2 2 1 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.6 EGC40596.1 - 8.7e-06 25.8 0.0 2.3e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.14 EGC40596.1 - 2.9e-05 23.6 0.5 7.4e-05 22.3 0.5 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_4 PF13704.6 EGC40596.1 - 0.037 14.5 0.7 0.037 14.5 0.7 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 2 DUF5607 PF18355.1 EGC40596.1 - 0.1 13.0 0.0 0.25 11.8 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF5607) Scramblase PF03803.15 EGC40597.1 - 3.1e-19 69.1 0.6 7.8e-09 35.1 0.4 2.1 2 0 0 2 2 2 2 Scramblase FNIP PF05725.12 EGC40598.1 - 1.9e-112 367.2 92.8 2e-12 47.0 1.1 17.4 9 3 12 21 21 21 21 FNIP Repeat DUF1769 PF08588.10 EGC40598.1 - 0.0011 19.1 17.8 0.81 9.9 0.0 9.9 8 6 4 12 12 12 2 Protein of unknown function (DUF1769) Strep_SA_rep PF06696.11 EGC40599.1 - 0.59 10.2 2.5 4.1 7.5 0.7 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat DUF5308 PF17233.2 EGC40601.1 - 0.041 14.1 2.4 0.058 13.6 2.4 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF5308) Zip PF02535.22 EGC40601.1 - 0.58 9.3 5.9 0.71 9.0 5.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Presenilin PF01080.17 EGC40601.1 - 5.3 5.7 7.3 5.7 5.6 7.3 1.1 1 0 0 1 1 1 0 Presenilin zf-RING_2 PF13639.6 EGC40602.1 - 8.8e-10 38.8 10.7 2.1e-09 37.6 10.7 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.6 EGC40602.1 - 7e-08 32.2 9.3 1.5e-07 31.1 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.25 EGC40602.1 - 1.7e-07 31.0 11.0 5.5e-07 29.4 11.0 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.6 EGC40602.1 - 2.5e-07 30.4 7.0 5.8e-07 29.3 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.7 EGC40602.1 - 1e-05 25.7 6.6 5.4e-05 23.4 6.6 2.3 1 0 0 1 1 1 1 RING-H2 zinc finger domain zf-RING_UBOX PF13445.6 EGC40602.1 - 0.00018 21.4 5.5 0.00055 19.9 5.5 1.9 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.6 EGC40602.1 - 0.0017 18.5 8.3 0.0017 18.5 8.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-ANAPC11 PF12861.7 EGC40602.1 - 0.013 15.5 0.9 0.029 14.4 0.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_5 PF14634.6 EGC40602.1 - 0.018 15.0 9.8 0.053 13.5 9.8 1.9 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.6 EGC40602.1 - 0.032 14.0 9.1 0.069 13.0 9.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF1272 PF06906.11 EGC40602.1 - 0.16 12.1 6.4 0.39 10.8 6.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_10 PF16685.5 EGC40602.1 - 0.18 12.0 3.5 0.46 10.7 3.5 1.6 1 0 0 1 1 1 0 zinc RING finger of MSL2 Sigma_reg_N PF13800.6 EGC40602.1 - 0.29 11.4 3.9 0.79 10.1 3.9 1.8 1 0 0 1 1 1 0 Sigma factor regulator N-terminal zf-RING_11 PF17123.5 EGC40602.1 - 0.44 10.3 7.1 1 9.1 7.1 1.7 1 0 0 1 1 1 0 RING-like zinc finger Zn_ribbon_17 PF17120.5 EGC40602.1 - 2.2 7.9 5.9 4.5 7.0 5.9 1.5 1 0 0 1 1 1 0 Zinc-ribbon, C4HC2 type RhoGAP PF00620.27 EGC40604.1 - 1.9e-36 125.2 0.2 4.7e-36 123.9 0.2 1.7 1 0 0 1 1 1 1 RhoGAP domain EGF_2 PF07974.13 EGC40605.1 - 1.5e-05 25.2 23.5 6e-05 23.3 10.6 2.6 2 0 0 2 2 2 2 EGF-like domain EGF_Tenascin PF18720.1 EGC40605.1 - 0.0019 18.2 8.4 0.0062 16.5 5.2 2.4 2 0 0 2 2 2 1 Tenascin EGF domain TIG PF01833.24 EGC40605.1 - 0.002 18.2 1.0 0.002 18.2 1.0 3.7 3 1 0 3 3 3 1 IPT/TIG domain Laminin_EGF PF00053.24 EGC40605.1 - 0.69 10.1 15.9 0.025 14.7 8.2 2.4 2 0 0 2 2 2 0 Laminin EGF domain hEGF PF12661.7 EGC40605.1 - 1.6 9.5 20.2 0.92 10.2 5.5 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_alliinase PF04863.13 EGC40605.1 - 2.6 8.5 7.9 0.24 11.8 2.5 2.1 2 0 0 2 2 2 0 Alliinase EGF-like domain DUF3139 PF11337.8 EGC40606.1 - 0.013 16.1 2.1 0.027 15.1 2.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3139) SUFU PF05076.13 EGC40606.1 - 0.064 13.2 0.0 0.07 13.1 0.0 1.1 1 0 0 1 1 1 0 Suppressor of fused protein (SUFU) Arm PF00514.23 EGC40607.1 - 1.1e-10 41.1 7.0 1.6 8.9 0.1 6.5 6 1 0 6 6 6 5 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.6 EGC40607.1 - 0.037 14.3 0.7 2.7 8.3 0.0 3.2 2 1 2 4 4 4 0 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.6 EGC40607.1 - 0.14 12.5 0.0 6 7.3 0.0 2.5 2 0 0 2 2 2 0 HEAT repeats FNIP PF05725.12 EGC40609.1 - 1.6e-68 226.6 54.6 2.4e-11 43.6 0.1 10.8 7 3 6 13 13 13 10 FNIP Repeat ketoacyl-synt PF00109.26 EGC40610.1 - 1.4e-61 208.2 0.0 2.2e-61 207.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.21 EGC40610.1 - 3.8e-43 148.2 0.0 7e-43 147.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.22 EGC40610.1 - 6.4e-33 113.3 0.0 1e-31 109.4 0.0 2.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.10 EGC40610.1 - 4.9e-25 88.5 0.0 1.1e-24 87.4 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.12 EGC40610.1 - 4.6e-22 78.6 3.8 6.6e-21 74.9 0.0 3.9 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.6 EGC40610.1 - 4.2e-20 72.2 0.0 6.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KAsynt_C_assoc PF16197.5 EGC40610.1 - 8e-17 61.7 0.4 3.1e-16 59.8 0.1 2.3 2 0 0 2 2 2 1 Ketoacyl-synthetase C-terminal extension ADH_zinc_N_2 PF13602.6 EGC40610.1 - 1.7e-08 35.6 0.0 1e-07 33.1 0.0 2.3 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.12 EGC40610.1 - 1.4e-06 28.2 0.0 3.3e-06 26.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.25 EGC40610.1 - 4.1e-06 27.1 0.0 9.8e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.6 EGC40610.1 - 8.6e-06 25.7 0.0 2.8e-05 24.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.23 EGC40610.1 - 6.2e-05 22.5 0.0 0.00015 21.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.12 EGC40610.1 - 0.00011 22.7 0.0 0.00039 21.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC40610.1 - 0.0087 15.9 5.4 0.14 12.0 0.0 4.2 4 0 0 4 4 4 1 Methyltransferase domain DUF1430 PF07242.11 EGC40610.1 - 0.018 15.3 3.2 0.038 14.3 0.5 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1430) GDP_Man_Dehyd PF16363.5 EGC40610.1 - 0.021 14.3 0.4 0.043 13.2 0.4 1.5 1 0 0 1 1 1 0 GDP-mannose 4,6 dehydratase FNIP PF05725.12 EGC40611.1 - 2.6e-51 171.5 63.3 5e-09 36.2 0.1 9.0 5 1 5 10 10 10 10 FNIP Repeat DUF5109 PF17134.4 EGC40611.1 - 0.0082 16.0 0.0 2 8.3 0.0 2.5 1 1 1 2 2 2 2 Domain of unknown function (DUF5109) Secretin_N_2 PF07655.13 EGC40611.1 - 0.77 10.3 8.6 1.6 9.4 8.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.12 EGC40612.1 - 7.7e-57 189.2 63.1 9.1e-11 41.8 0.3 10.5 7 2 3 10 10 10 10 FNIP Repeat Secretin_N_2 PF07655.13 EGC40612.1 - 0.88 10.2 12.8 1.3 9.6 11.7 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain FNIP PF05725.12 EGC40613.1 - 3.9e-112 366.2 139.7 2.1e-11 43.8 0.4 19.8 12 3 12 24 24 24 24 FNIP Repeat FNIP PF05725.12 EGC40614.1 - 5.9e-70 231.2 105.1 3.2e-12 46.4 0.1 10.8 2 1 9 13 13 13 13 FNIP Repeat Secretin_N_2 PF07655.13 EGC40614.1 - 1.3 9.6 13.3 3.5 8.2 13.3 1.7 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.12 EGC40615.1 - 4.7e-29 100.3 72.0 1e-05 25.6 1.8 12.4 14 1 0 14 14 14 8 FNIP Repeat PI3_PI4_kinase PF00454.27 EGC40615.1 - 5.8e-05 23.0 2.3 0.025 14.4 0.1 3.3 3 0 0 3 3 3 2 Phosphatidylinositol 3- and 4-kinase XhlA PF10779.9 EGC40615.1 - 1.3 9.3 4.8 5.5 7.3 4.8 2.2 1 0 0 1 1 1 0 Haemolysin XhlA GABP-alpha PF11620.8 EGC40616.1 - 0.11 12.7 4.5 0.078 13.2 2.4 1.8 2 0 0 2 2 2 0 GA-binding protein alpha chain DUF3449 PF11931.8 EGC40616.1 - 0.47 10.2 4.1 3.5 7.4 1.3 2.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3449) FNIP PF05725.12 EGC40617.1 - 3.3e-24 84.8 66.8 4.4e-06 26.8 0.5 11.1 5 2 6 12 12 12 9 FNIP Repeat zf-B_box PF00643.24 EGC40617.1 - 0.00043 20.4 6.0 0.00098 19.2 6.0 1.5 1 0 0 1 1 1 1 B-box zinc finger Acyl-CoA_ox_N PF14749.6 EGC40617.1 - 0.024 15.2 2.1 0.051 14.1 2.1 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ALO PF04030.14 EGC40617.1 - 0.054 13.3 0.1 0.1 12.4 0.1 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase Strep_SA_rep PF06696.11 EGC40618.1 - 0.63 10.1 2.5 4.1 7.5 0.7 2.7 2 0 0 2 2 2 0 Streptococcal surface antigen repeat FAM91_C PF14648.6 EGC40619.1 - 6.5e-150 499.7 0.6 1.8e-149 498.3 0.6 1.7 1 1 0 1 1 1 1 FAM91 C-terminus FAM91_N PF14647.6 EGC40619.1 - 1.2e-120 402.5 6.3 1.8e-120 401.9 6.3 1.2 1 0 0 1 1 1 1 FAM91 N-terminus Methyltransf_23 PF13489.6 EGC40620.1 - 4e-19 69.0 0.0 5e-19 68.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.6 EGC40620.1 - 1.9e-14 53.8 0.0 3e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.12 EGC40620.1 - 2.5e-13 50.5 0.0 4.2e-13 49.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.6 EGC40620.1 - 5.1e-12 46.3 0.0 8.8e-12 45.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.12 EGC40620.1 - 2.7e-11 44.1 0.0 4.5e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.18 EGC40620.1 - 3.5e-06 26.5 0.0 4.7e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.14 EGC40620.1 - 3.6e-05 23.4 0.0 7.5e-05 22.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain NNMT_PNMT_TEMT PF01234.17 EGC40620.1 - 0.0012 18.1 0.1 0.69 9.0 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family RrnaAD PF00398.20 EGC40620.1 - 0.0015 17.6 0.1 0.0019 17.3 0.1 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.7 EGC40620.1 - 0.0044 17.0 0.0 0.0085 16.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.17 EGC40620.1 - 0.0053 16.2 0.0 0.022 14.2 0.0 2.0 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_17 PF12692.7 EGC40620.1 - 0.046 13.7 0.0 0.17 11.9 0.0 1.8 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase DUF938 PF06080.12 EGC40620.1 - 0.091 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938) zf-C2H2_jaz PF12171.8 EGC40621.1 - 0.2 12.0 0.1 0.2 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding # # Program: hmmscan # Version: 3.2.1 (June 2018) # Pipeline mode: SCAN # Query file: /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_purpureum-v1.0/GCA_000190715.1_v1.0_protein.faa # Target file: /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm # Option settings: /oak/stanford/groups/akundaje/marinovg/programs/hmmer-3.2.1/bin/hmmscan -o /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_purpureum-v1.0/GCA_000190715.1_v1.0_protein.PFam32-A --tblout /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_purpureum-v1.0/GCA_000190715.1_v1.0_protein.PFam32-A.tblout --cpu 20 /oak/stanford/groups/akundaje/marinovg/genomes/PFam/PFam32.0/Pfam-A.hmm /oak/stanford/groups/akundaje/marinovg/genomes/Mycetozoa/Dictyostelium_purpureum-v1.0/GCA_000190715.1_v1.0_protein.faa # Current dir: /oak/stanford/groups/akundaje/marinovg/genomes # Date: Mon Mar 25 10:36:59 2019 # [ok]