# --- full sequence ---- --- best 1 domain ---- --- domain number estimation ---- # target name accession query name accession E-value score bias E-value score bias exp reg clu ov env dom rep inc description of target #------------------- ---------- -------------------- ---------- --------- ------ ----- --------- ------ ----- --- --- --- --- --- --- --- --- --------------------- Pex14_N PF04695.8 EGC28223.1 - 0.06 13.3 3.7 0.098 12.7 2.6 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region COPI_assoc PF08507.5 EGC28226.1 - 2.4e-08 33.7 2.2 3.9e-08 33.0 1.5 1.3 1 0 0 1 1 1 1 COPI associated protein PepSY_TM_1 PF13172.1 EGC28226.1 - 0.069 12.9 0.3 1.6 8.6 0.0 2.5 2 0 0 2 2 2 0 PepSY-associated TM helix DUF4345 PF14248.1 EGC28226.1 - 0.071 12.5 4.6 0.046 13.1 1.9 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4345) Ni_hydr_CYTB PF01292.15 EGC28226.1 - 0.076 12.3 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic cytochrome b561 TMEM220 PF15071.1 EGC28226.1 - 0.62 10.5 4.4 8.4 6.8 0.4 2.2 1 1 1 2 2 2 0 Transmembrane family 220, helix Annexin PF00191.15 EGC28227.1 - 1.3e-39 133.9 6.1 7.2e-13 48.2 0.1 4.2 4 0 0 4 4 4 4 Annexin Cohesin_load PF10345.4 EGC28228.1 - 4.2e-06 25.2 1.7 8.1e-06 24.3 1.2 1.7 1 1 0 1 1 1 1 Cohesin loading factor PTS_IIB PF02302.12 EGC28228.1 - 0.13 12.7 0.2 4.8 7.7 0.1 2.2 2 0 0 2 2 2 0 PTS system, Lactose/Cellobiose specific IIB subunit FNIP PF05725.7 EGC28231.1 - 8.9e-42 140.7 54.5 7.5e-09 35.4 0.1 9.4 2 2 5 9 9 9 9 FNIP Repeat DUF4097 PF13349.1 EGC28232.1 - 0.027 14.0 1.2 0.94 9.0 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4097) MATH PF00917.21 EGC28234.1 - 0.0009 19.4 2.4 0.0013 18.9 1.7 1.2 1 0 0 1 1 1 1 MATH domain zf-TRAF PF02176.13 EGC28235.1 - 2.4e-18 66.2 18.4 1.3e-13 51.1 5.2 3.9 2 1 2 4 4 4 2 TRAF-type zinc finger Sina PF03145.11 EGC28235.1 - 1e-05 25.3 18.3 0.0024 17.5 1.2 3.9 1 1 3 4 4 4 3 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EGC28235.1 - 0.0021 17.6 5.9 0.0021 17.6 4.1 3.9 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) bZIP_2 PF07716.10 EGC28235.1 - 0.032 14.0 1.0 12 5.7 0.1 3.0 2 0 0 2 2 2 0 Basic region leucine zipper LRR_1 PF00560.28 EGC28235.1 - 0.1 12.7 2.6 12 6.4 0.2 3.5 2 0 0 2 2 2 0 Leucine Rich Repeat DUF2681 PF10883.3 EGC28235.1 - 0.45 10.7 4.0 0.2 11.9 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) LRR_4 PF12799.2 EGC28235.1 - 1.4 8.6 15.5 2.7 7.7 9.4 2.6 2 1 0 2 2 2 0 Leucine Rich repeats (2 copies) DMPK_coil PF08826.5 EGC28235.1 - 4.4 7.2 6.6 2.5 8.0 0.5 3.1 2 1 1 3 3 3 0 DMPK coiled coil domain like TMF_DNA_bd PF12329.3 EGC28235.1 - 8.8 6.2 12.7 12 5.7 4.9 3.2 2 1 1 3 3 3 0 TATA element modulatory factor 1 DNA binding GATA PF00320.22 EGC28236.1 - 1.7e-14 52.8 2.5 5e-14 51.3 1.7 1.9 1 0 0 1 1 1 1 GATA zinc finger zf-C3HC4_3 PF13920.1 EGC28236.1 - 0.13 11.9 0.2 0.23 11.1 0.1 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) PfkB PF00294.19 EGC28237.1 - 3.9e-06 26.2 0.0 4.7e-06 25.9 0.0 1.1 1 0 0 1 1 1 1 pfkB family carbohydrate kinase PseudoU_synth_2 PF00849.17 EGC28238.1 - 9.3e-30 103.6 0.0 9.3e-30 103.6 0.0 2.9 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 EGC28238.1 - 0.0078 15.6 0.2 0.019 14.4 0.2 1.7 1 0 0 1 1 1 1 S4 domain Ras PF00071.17 EGC28239.1 - 7.2e-19 67.7 0.5 9.1e-19 67.4 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28239.1 - 7.5e-06 26.4 0.1 1.3e-05 25.6 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein SSP160 PF06933.6 EGC28241.1 - 0.18 9.7 7.5 0.26 9.2 5.2 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF2967 PF11179.3 EGC28242.1 - 1.7 8.0 8.9 1.8 7.9 6.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Pkinase_Tyr PF07714.12 EGC28243.1 - 3.1e-25 88.7 0.0 1.3e-22 80.0 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGC28243.1 - 6e-24 84.5 0.2 4.3e-23 81.7 0.1 1.9 1 1 1 2 2 2 1 Protein kinase domain Kdo PF06293.9 EGC28243.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC28243.1 - 0.0044 16.3 0.0 0.0079 15.5 0.0 1.5 1 0 0 1 1 1 1 RIO1 family Spindle_Spc25 PF08234.7 EGC28243.1 - 0.096 12.6 0.1 8.3 6.4 0.0 2.5 2 0 0 2 2 2 0 Chromosome segregation protein Spc25 CAF1 PF04857.15 EGC28247.1 - 3.4e-65 220.0 0.2 7.8e-65 218.7 0.1 1.6 1 1 0 1 1 1 1 CAF1 family ribonuclease Aminotran_3 PF00202.16 EGC28248.1 - 2.3e-104 348.9 0.0 2.8e-104 348.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGC28248.1 - 0.00036 19.6 0.0 0.00064 18.7 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II Homeobox PF00046.24 EGC28249.1 - 4.9e-18 64.4 5.3 1.6e-10 40.4 0.5 2.8 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 EGC28249.1 - 3.2e-07 29.9 1.2 0.0026 17.4 0.0 3.3 2 0 0 2 2 2 2 Homeobox KN domain YniB PF14002.1 EGC28249.1 - 0.17 11.3 0.2 0.35 10.3 0.1 1.4 1 0 0 1 1 1 0 YniB-like protein Peptidase_M50 PF02163.17 EGC28250.1 - 3.7e-17 61.8 0.0 2.5e-16 59.2 0.0 2.1 1 1 0 1 1 1 1 Peptidase family M50 PDZ PF00595.19 EGC28250.1 - 0.00037 20.6 0.0 0.001 19.1 0.0 1.7 1 0 0 1 1 1 1 PDZ domain (Also known as DHR or GLGF) DUF3446 PF11928.3 EGC28250.1 - 0.029 14.5 4.9 0.066 13.4 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3446) SecG PF03840.9 EGC28250.1 - 0.036 13.7 1.2 0.13 11.9 0.8 2.1 1 0 0 1 1 1 0 Preprotein translocase SecG subunit PDZ_2 PF13180.1 EGC28250.1 - 0.065 13.1 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 PDZ domain ATP1G1_PLM_MAT8 PF02038.11 EGC28250.1 - 0.11 11.4 0.6 0.31 10.0 0.0 2.0 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family NPCC PF08058.6 EGC28250.1 - 0.5 10.2 6.0 0.12 12.2 1.2 2.1 2 0 0 2 2 2 0 Nuclear pore complex component SR-25 PF10500.4 EGC28250.1 - 4.8 6.5 13.3 6.6 6.1 9.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CRAL_TRIO PF00650.15 EGC28251.1 - 2.5e-46 157.0 0.6 3.7e-46 156.5 0.2 1.4 2 0 0 2 2 2 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGC28251.1 - 2e-12 47.2 0.3 3e-12 46.6 0.2 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGC28251.1 - 2e-10 40.6 0.6 5.2e-09 36.1 0.1 3.0 3 0 0 3 3 3 1 CRAL/TRIO, N-terminal domain vATP-synt_AC39 PF01992.11 EGC28253.1 - 2.7e-94 316.0 0.6 3.3e-94 315.7 0.4 1.0 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit CH PF00307.26 EGC28254.1 - 2.6e-12 46.7 0.1 2.9e-12 46.5 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC28254.1 - 0.00025 20.6 0.0 0.00028 20.4 0.0 1.3 1 0 0 1 1 1 1 CAMSAP CH domain ANTH PF07651.11 EGC28254.1 - 0.11 11.1 0.0 0.12 11.0 0.0 1.1 1 0 0 1 1 1 0 ANTH domain Methyltransf_28 PF02636.12 EGC28255.1 - 8.7e-68 228.4 0.0 1.1e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase PI31_Prot_N PF11566.3 EGC28256.1 - 6.9e-20 71.2 0.1 9.3e-20 70.7 0.1 1.1 1 0 0 1 1 1 1 PI31 proteasome regulator N-terminal PI31_Prot_C PF08577.6 EGC28256.1 - 2.4e-11 44.1 17.5 2.4e-11 44.1 12.1 2.5 2 0 0 2 2 2 1 PI31 proteasome regulator Pkinase PF00069.20 EGC28257.1 - 3.7e-55 186.8 0.0 4.3e-55 186.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28257.1 - 1.1e-23 83.6 0.0 1.4e-23 83.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28257.1 - 1.3e-06 27.5 0.0 1.9e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC28257.1 - 0.0067 16.1 0.0 0.34 10.5 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC28257.1 - 0.011 15.1 0.1 0.024 13.9 0.0 1.5 2 0 0 2 2 2 0 RIO1 family Seadorna_VP7 PF07387.6 EGC28257.1 - 0.043 12.6 0.0 0.068 11.9 0.0 1.3 1 0 0 1 1 1 0 Seadornavirus VP7 Kdo PF06293.9 EGC28257.1 - 0.12 11.4 0.0 0.16 11.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 EGC28259.1 - 6.4e-10 38.6 8.1 1.5e-09 37.5 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC28259.1 - 2.9e-08 33.2 5.6 5.3e-08 32.4 3.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28259.1 - 7.4e-07 28.7 9.9 2e-06 27.3 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28259.1 - 1.1e-06 28.5 9.1 2.7e-06 27.2 6.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC28259.1 - 2.9e-05 23.7 7.3 7.2e-05 22.4 5.1 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC28259.1 - 0.00025 20.8 9.3 0.00064 19.5 6.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC28259.1 - 0.0007 19.6 4.8 0.0018 18.3 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGC28259.1 - 0.0015 18.0 8.1 0.0038 16.7 5.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGC28259.1 - 0.0056 16.4 1.4 0.013 15.3 0.9 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC28259.1 - 0.0096 15.6 6.0 0.034 13.8 4.2 2.0 1 0 0 1 1 1 1 RING-type zinc-finger DZR PF12773.2 EGC28259.1 - 0.37 10.6 4.6 0.96 9.3 3.1 1.7 1 1 0 1 1 1 0 Double zinc ribbon zf-MIZ PF02891.15 EGC28259.1 - 2.2 7.8 12.3 0.2 11.2 5.1 1.8 2 0 0 2 2 1 0 MIZ/SP-RING zinc finger DUF2413 PF10310.4 EGC28260.1 - 0.65 8.7 22.7 0.98 8.1 15.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) DUF2894 PF11445.3 EGC28260.1 - 4 7.6 18.1 6.6 6.9 12.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2894) DDE_Tnp_4 PF13359.1 EGC28261.1 - 5.8e-10 38.9 0.0 8.2e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease Pyridoxal_deC PF00282.14 EGC28261.1 - 0.06 11.7 0.0 0.093 11.1 0.0 1.3 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain DUF1528 PF07515.6 EGC28261.1 - 0.066 13.2 0.3 0.16 12.0 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1528) Abhydrolase_1 PF00561.15 EGC28262.1 - 0.00017 21.2 0.0 0.00068 19.2 0.0 1.7 1 1 1 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC28262.1 - 0.00051 19.9 0.0 0.00056 19.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EGC28262.1 - 0.0014 17.8 0.0 0.0017 17.5 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3089) Ser_hydrolase PF06821.8 EGC28262.1 - 0.0037 16.8 0.0 0.0045 16.6 0.0 1.2 1 0 0 1 1 1 1 Serine hydrolase Abhydrolase_5 PF12695.2 EGC28262.1 - 0.009 15.7 0.0 0.01 15.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF900 PF05990.7 EGC28262.1 - 0.011 15.0 0.0 0.013 14.8 0.0 1.1 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EGC28262.1 - 0.024 14.2 0.0 0.027 14.0 0.0 1.2 1 0 0 1 1 1 0 PGAP1-like protein DUF676 PF05057.9 EGC28262.1 - 0.033 13.4 0.1 0.045 13.0 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) mIF3 PF14877.1 EGC28262.1 - 0.04 13.2 0.1 0.065 12.5 0.0 1.3 1 1 0 1 1 1 0 Mitochondrial translation initiation factor Lipase_3 PF01764.20 EGC28262.1 - 0.13 11.8 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) SIP1 PF04938.7 EGC28263.1 - 5.4e-43 147.0 10.8 6e-42 143.5 7.5 2.0 1 1 0 1 1 1 1 Survival motor neuron (SMN) interacting protein 1 (SIP1) GalP_UDP_transf PF01087.17 EGC28263.1 - 0.024 14.6 2.8 0.049 13.6 2.0 1.7 1 1 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Nop14 PF04147.7 EGC28263.1 - 0.099 10.5 14.1 0.13 10.1 9.8 1.2 1 0 0 1 1 1 0 Nop14-like family SDA1 PF05285.7 EGC28263.1 - 0.23 10.7 13.4 0.32 10.2 9.3 1.1 1 0 0 1 1 1 0 SDA1 Presenilin PF01080.12 EGC28265.1 - 1.1e-66 225.3 39.0 9.9e-47 159.6 15.1 2.7 1 1 2 3 3 3 2 Presenilin Tic20 PF09685.5 EGC28266.1 - 0.0014 18.6 8.6 0.002 18.0 5.9 1.2 1 0 0 1 1 1 1 Tic20-like protein tRNA-synt_1c PF00749.16 EGC28266.1 - 0.031 12.9 1.0 0.05 12.2 0.7 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain DUF2101 PF09874.4 EGC28266.1 - 0.074 12.5 6.0 0.13 11.7 4.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) RDD PF06271.7 EGC28266.1 - 0.14 12.0 5.8 0.95 9.3 4.4 1.9 1 1 1 2 2 2 0 RDD family ATP-synt PF00231.14 EGC28267.1 - 5.6e-34 117.8 0.0 6.7e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 ATP synthase P12 PF12669.2 EGC28269.1 - 0.17 12.1 2.7 0.34 11.1 1.9 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF2463 PF09591.5 EGC28270.1 - 0.021 14.4 0.3 0.032 13.8 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2463) Big_2 PF02368.13 EGC28271.1 - 0.0029 17.4 3.2 2.2 8.1 0.1 3.7 4 0 0 4 4 4 2 Bacterial Ig-like domain (group 2) PYST-C1 PF09690.5 EGC28272.1 - 3.5 7.3 13.4 4.9 6.8 9.3 1.2 1 0 0 1 1 1 0 Plasmodium yoelii subtelomeric region (PYST-C1) PH PF00169.24 EGC28274.1 - 1.6e-27 95.7 16.7 7e-17 61.5 0.6 4.4 4 1 0 4 4 4 2 PH domain LIM PF00412.17 EGC28274.1 - 5e-23 80.9 26.4 2.7e-10 40.1 3.1 3.5 3 0 0 3 3 3 3 LIM domain PH_11 PF15413.1 EGC28274.1 - 1e-07 32.1 19.6 0.00019 21.6 4.1 4.9 3 2 1 4 4 4 2 Pleckstrin homology domain PH_8 PF15409.1 EGC28274.1 - 4e-05 23.5 0.2 0.00018 21.5 0.1 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EGC28274.1 - 0.00023 21.3 3.9 5.4 7.1 0.0 4.5 3 1 0 3 3 3 2 Pleckstrin homology domain PH_3 PF14593.1 EGC28274.1 - 0.00033 20.5 0.3 0.00033 20.5 0.2 3.2 4 0 0 4 4 4 1 PH domain PH_6 PF15406.1 EGC28274.1 - 0.063 13.3 1.3 2.5 8.2 0.0 2.7 2 0 0 2 2 2 0 Pleckstrin homology domain zf-dskA_traR PF01258.12 EGC28274.1 - 5.2 6.9 9.2 1.5 8.5 0.3 3.5 3 1 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger RNA_pol_Rpb1_5 PF04998.12 EGC28275.1 - 0.13 11.4 11.9 0.25 10.5 8.2 1.4 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Cyclin PF08613.6 EGC28276.1 - 6.2e-05 23.4 2.8 6.2e-05 23.4 2.0 2.5 2 2 0 2 2 2 1 Cyclin Rab5ip PF07019.7 EGC28278.1 - 1.9e-21 75.9 5.6 2.4e-21 75.6 3.9 1.2 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) DUF2892 PF11127.3 EGC28278.1 - 0.042 13.6 0.1 0.082 12.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2892) FNIP PF05725.7 EGC28279.1 - 4.1e-43 145.0 47.1 9.6e-12 44.6 0.3 10.5 7 2 5 13 13 13 9 FNIP Repeat Ribonuclease_T2 PF00445.13 EGC28280.1 - 0.1 12.2 0.4 0.11 12.0 0.3 1.1 1 0 0 1 1 1 0 Ribonuclease T2 family Lactamase_B_4 PF13691.1 EGC28282.1 - 0.047 13.1 0.0 0.074 12.5 0.0 1.3 1 0 0 1 1 1 0 tRNase Z endonuclease HIT PF01230.18 EGC28284.1 - 7.2e-26 90.5 0.0 9.7e-26 90.1 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGC28284.1 - 1.6e-08 34.7 0.0 2.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding PARP PF00644.15 EGC28285.1 - 5.1e-06 26.0 6.9 5.1e-06 26.0 4.8 2.4 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain TRP PF06011.7 EGC28285.1 - 0.072 11.6 1.0 0.13 10.7 0.7 1.4 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel ABC2_membrane_3 PF12698.2 EGC28285.1 - 0.14 11.1 19.6 0.11 11.5 4.9 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein Kei1 PF08552.6 EGC28285.1 - 0.29 10.7 6.1 0.072 12.7 0.6 2.2 3 0 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 Pex14_N PF04695.8 EGC28285.1 - 0.33 11.0 11.3 0.043 13.8 2.9 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF912 PF06024.7 EGC28285.1 - 1 9.4 20.4 0.25 11.3 6.0 3.2 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Peptidase_M56 PF05569.6 EGC28285.1 - 3.6 6.4 6.9 0.32 9.9 0.5 2.0 2 0 0 2 2 2 0 BlaR1 peptidase M56 Ashwin PF15323.1 EGC28285.1 - 7.2 6.5 19.6 0.15 12.0 6.1 2.2 2 0 0 2 2 2 0 Developmental protein UQ_con PF00179.21 EGC28286.1 - 4.1e-44 149.4 0.0 4.5e-44 149.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGC28286.1 - 0.11 12.4 0.1 0.16 11.9 0.0 1.5 1 1 0 1 1 1 0 RWD domain DUF1947 PF09183.5 EGC28287.1 - 0.051 13.3 5.1 4.8 7.0 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1947) DUF4582 PF15189.1 EGC28287.1 - 0.061 12.5 1.5 0.083 12.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4582) DUF4013 PF13197.1 EGC28288.1 - 0.0084 15.4 8.0 0.014 14.7 5.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4013) QLQ PF08880.6 EGC28288.1 - 0.12 11.8 0.0 0.26 10.7 0.0 1.6 1 0 0 1 1 1 0 QLQ DUF2701 PF10857.3 EGC28288.1 - 4.6 7.0 14.7 4.4 7.1 3.8 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) MRP-L20 PF12824.2 EGC28289.1 - 2.9e-05 24.0 1.0 0.0001 22.2 0.7 2.1 1 1 0 1 1 1 1 Mitochondrial ribosomal protein subunit L20 GPCR_chapero_1 PF11904.3 EGC28290.1 - 9.4e-62 208.8 3.6 1.9e-61 207.9 2.5 1.4 1 0 0 1 1 1 1 GPCR-chaperone Ank_2 PF12796.2 EGC28290.1 - 1.1e-07 32.0 0.0 2.1e-07 31.1 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC28290.1 - 1.8e-06 28.2 0.0 3.4e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGC28290.1 - 0.00014 21.5 0.1 0.00071 19.2 0.0 2.2 3 0 0 3 3 3 1 Ankyrin repeat Ank_5 PF13857.1 EGC28290.1 - 0.00018 21.5 0.0 0.00037 20.6 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC28290.1 - 0.036 14.2 0.0 0.42 10.9 0.0 2.7 3 0 0 3 3 3 0 Ankyrin repeat SAE2 PF08573.5 EGC28291.1 - 1.1e-13 51.6 4.2 3.4e-10 40.4 0.3 5.4 2 2 2 4 4 4 2 DNA repair protein endonuclease SAE2/CtIP C-terminus F-box-like PF12937.2 EGC28294.1 - 2.9e-10 39.6 0.6 8.9e-10 38.1 0.4 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC28294.1 - 9.2e-07 28.3 0.3 2.9e-06 26.7 0.2 2.0 1 0 0 1 1 1 1 F-box domain WD40 PF00400.27 EGC28294.1 - 1.8e-05 24.4 0.2 0.00016 21.4 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat PQQ_2 PF13360.1 EGC28294.1 - 0.0063 16.0 0.0 0.022 14.2 0.0 1.8 2 0 0 2 2 2 1 PQQ-like domain Homeobox PF00046.24 EGC28295.1 - 2.3e-10 39.9 8.0 2.9e-06 26.7 0.1 2.7 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 EGC28295.1 - 3.5e-07 29.7 0.4 0.027 14.1 0.0 2.6 2 0 0 2 2 2 2 Homeobox KN domain HSP20 PF00011.16 EGC28296.1 - 7.7e-16 57.8 0.7 3.7e-15 55.6 0.5 1.8 1 1 0 1 1 1 1 Hsp20/alpha crystallin family YonK PF09642.5 EGC28296.1 - 0.24 11.1 2.3 0.53 10.0 0.3 2.4 3 0 0 3 3 3 0 YonK protein DUF4459 PF14673.1 EGC28297.1 - 0.085 12.5 0.5 0.15 11.7 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4459) Metallophos_2 PF12850.2 EGC28299.1 - 1.6e-22 80.0 0.1 1.9e-22 79.7 0.0 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGC28299.1 - 0.00051 19.4 0.4 0.17 11.2 0.1 2.5 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Phage_Treg PF04761.7 EGC28300.1 - 1.1 9.0 3.6 0.84 9.4 0.3 2.0 1 1 1 2 2 2 0 Lactococcus bacteriophage putative transcription regulator FHA PF00498.21 EGC28301.1 - 0.00014 21.9 0.2 0.00034 20.6 0.1 1.6 2 0 0 2 2 2 1 FHA domain DUF4033 PF13225.1 EGC28301.1 - 0.011 15.3 0.2 0.015 14.8 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) RRM_1 PF00076.17 EGC28303.1 - 2.5e-17 62.2 0.0 3.9e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC28303.1 - 1.6e-14 53.6 0.0 2.7e-14 52.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC28303.1 - 3.2e-10 39.6 0.0 6.3e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF2782 PF11191.3 EGC28303.1 - 0.045 13.7 0.0 0.069 13.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2782) PH PF00169.24 EGC28304.1 - 8.3e-12 45.2 2.9 8.3e-12 45.2 2.0 3.0 2 2 0 2 2 2 1 PH domain PH_8 PF15409.1 EGC28304.1 - 8e-08 32.2 4.7 4.1e-05 23.5 0.3 3.3 2 1 0 2 2 2 2 Pleckstrin homology domain PH_11 PF15413.1 EGC28304.1 - 6.5e-07 29.5 13.8 0.00012 22.2 9.5 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EGC28304.1 - 0.00013 21.7 0.4 0.45 10.4 0.1 2.7 2 1 0 2 2 2 2 PH domain GTP1_OBG PF01018.17 EGC28304.1 - 0.01 15.4 0.0 0.019 14.6 0.0 1.4 1 0 0 1 1 1 0 GTP1/OBG Mcp5_PH PF12814.2 EGC28304.1 - 0.67 9.8 0.0 0.67 9.8 0.0 3.9 4 2 1 5 5 5 0 Meiotic cell cortex C-terminal pleckstrin homology MRP-L27 PF09809.4 EGC28305.1 - 1e-12 47.6 0.6 1.2e-12 47.4 0.4 1.2 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L27 Prolactin_RP PF15172.1 EGC28305.1 - 0.71 9.1 3.4 1.9 7.7 2.4 1.8 1 1 0 1 1 1 0 Prolactin-releasing peptide ABC_membrane_2 PF06472.10 EGC28306.1 - 2.4e-48 164.6 8.0 2.9e-43 148.0 4.9 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGC28306.1 - 2.1e-17 63.7 0.3 6.3e-17 62.1 0.0 2.0 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGC28306.1 - 0.00035 20.0 1.3 0.026 14.0 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC28306.1 - 0.00075 18.7 0.0 0.0021 17.2 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 DUF815 PF05673.8 EGC28306.1 - 0.0011 18.0 0.0 0.0023 16.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_16 PF13191.1 EGC28306.1 - 0.0035 17.3 0.0 0.0072 16.3 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain IstB_IS21 PF01695.12 EGC28306.1 - 0.023 14.1 0.0 0.051 12.9 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGC28306.1 - 0.067 12.3 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Sigma54_activat PF00158.21 EGC28306.1 - 0.073 12.5 0.0 0.15 11.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain Sigma54_activ_2 PF14532.1 EGC28306.1 - 0.082 12.9 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain WD40 PF00400.27 EGC28308.1 - 6e-10 38.6 8.3 6.6e-06 25.8 0.0 3.2 3 0 0 3 3 3 3 WD domain, G-beta repeat Methyltransf_31 PF13847.1 EGC28309.1 - 6.8e-16 58.2 1.0 1.2e-15 57.3 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC28309.1 - 2.2e-13 50.7 0.0 3.9e-13 49.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC28309.1 - 5.1e-13 49.0 0.0 8.4e-13 48.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC28309.1 - 6.2e-08 32.2 0.0 2e-07 30.5 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Cons_hypoth95 PF03602.10 EGC28309.1 - 1.2e-05 24.8 0.0 3.8e-05 23.1 0.0 1.8 1 1 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_12 PF08242.7 EGC28309.1 - 6.3e-05 23.3 0.3 0.00072 19.9 0.0 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGC28309.1 - 0.00011 21.7 0.1 0.00025 20.5 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGC28309.1 - 0.00017 21.3 0.0 0.0061 16.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC28309.1 - 0.00031 21.0 0.0 0.00075 19.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGC28309.1 - 0.00037 20.1 0.0 0.00066 19.2 0.0 1.4 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PrmA PF06325.8 EGC28309.1 - 0.00059 19.0 0.0 0.0012 18.0 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_15 PF09445.5 EGC28309.1 - 0.00069 19.2 0.2 0.0019 17.7 0.0 1.8 2 0 0 2 2 2 1 RNA cap guanine-N2 methyltransferase Methyltransf_11 PF08241.7 EGC28309.1 - 0.0015 18.9 0.0 0.0039 17.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Eco57I PF07669.6 EGC28309.1 - 0.0038 17.5 0.0 0.016 15.5 0.0 2.1 1 0 0 1 1 1 1 Eco57I restriction-modification methylase N6_Mtase PF02384.11 EGC28309.1 - 0.0041 16.2 0.0 0.0077 15.3 0.0 1.4 1 0 0 1 1 1 1 N-6 DNA Methylase Methyltransf_10 PF05971.7 EGC28309.1 - 0.0064 15.6 0.0 0.013 14.6 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF890) PCMT PF01135.14 EGC28309.1 - 0.011 15.2 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EGC28309.1 - 0.04 12.9 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase N6-adenineMlase PF10237.4 EGC28309.1 - 0.059 13.0 0.0 0.11 12.1 0.0 1.6 1 0 0 1 1 1 0 Probable N6-adenine methyltransferase MetW PF07021.7 EGC28309.1 - 0.061 12.7 0.1 0.19 11.1 0.1 1.9 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW DUF2870 PF11069.3 EGC28312.1 - 0.089 12.8 0.9 0.17 11.9 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) DUF1475 PF07343.6 EGC28314.1 - 0.27 10.5 2.0 1.8 7.8 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1475) Gly-zipper_OmpA PF13436.1 EGC28315.1 - 5.8 6.5 7.1 13 5.4 0.0 3.1 3 0 0 3 3 3 0 Glycine-zipper containing OmpA-like membrane domain Entericidin PF08085.6 EGC28316.1 - 0.079 12.7 0.6 0.17 11.7 0.4 1.5 1 0 0 1 1 1 0 Entericidin EcnA/B family DUF4615 PF15393.1 EGC28317.1 - 1.8e-09 37.8 0.5 1.8e-09 37.8 0.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4615) OSCP PF00213.13 EGC28317.1 - 3.4 7.4 7.9 1.6 8.5 0.2 2.2 2 0 0 2 2 2 0 ATP synthase delta (OSCP) subunit DUF1168 PF06658.7 EGC28317.1 - 7.5 6.0 21.6 19 4.7 15.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1168) DUF1910 PF08928.5 EGC28317.1 - 10 6.2 10.6 0.31 11.0 0.4 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF1910) TPR_11 PF13414.1 EGC28318.1 - 1.8e-25 88.3 10.5 1.5e-16 59.7 1.1 3.0 3 0 0 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGC28318.1 - 2.7e-23 80.5 8.2 5.3e-11 41.6 0.2 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC28318.1 - 1.2e-18 65.3 5.0 2.6e-08 33.1 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC28318.1 - 5.9e-15 53.8 10.3 1.3e-08 34.0 0.4 3.8 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC28318.1 - 3e-12 46.2 1.8 1.6e-10 40.7 0.7 2.5 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC28318.1 - 5.3e-11 41.8 6.7 2.4e-05 24.1 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC28318.1 - 1.2e-10 41.7 0.1 1.3e-07 32.0 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC28318.1 - 2.2e-10 39.5 0.7 4.1e-06 26.1 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC28318.1 - 1.3e-08 34.7 0.0 0.00011 22.4 0.0 3.9 2 1 2 4 4 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC28318.1 - 1.9e-06 28.1 2.8 3.3e-05 24.1 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGC28318.1 - 6.8e-06 25.7 1.8 2.4e-05 23.9 0.2 2.5 2 1 0 2 2 2 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_6 PF13174.1 EGC28318.1 - 3.4e-05 24.0 1.6 0.01 16.2 0.1 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC28318.1 - 0.0001 22.1 0.0 0.21 11.4 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC28318.1 - 0.0039 17.2 3.3 0.0092 16.1 2.3 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 FAT PF02259.18 EGC28318.1 - 0.015 14.3 3.5 0.18 10.7 2.4 2.3 1 1 0 1 1 1 0 FAT domain TPR_21 PF09976.4 EGC28318.1 - 0.025 14.4 2.6 0.54 10.1 0.6 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC28318.1 - 0.037 13.9 0.1 0.1 12.5 0.1 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.12 EGC28318.1 - 0.043 14.1 0.0 0.14 12.4 0.0 1.9 1 1 0 1 1 1 0 Bacterial transcriptional activator domain DUF3366 PF11846.3 EGC28318.1 - 0.053 13.4 1.6 0.054 13.3 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3366) Lambda_Kil PF06301.6 EGC28318.1 - 0.085 12.3 0.2 22 4.5 0.0 3.0 3 0 0 3 3 2 0 Bacteriophage lambda Kil protein PPR PF01535.15 EGC28318.1 - 0.14 12.1 2.9 0.31 11.1 0.0 3.0 3 0 0 3 3 2 0 PPR repeat MIT PF04212.13 EGC28318.1 - 0.21 11.5 13.9 0.42 10.5 0.4 4.6 4 1 1 5 5 5 0 MIT (microtubule interacting and transport) domain TPR_3 PF07720.7 EGC28318.1 - 0.25 11.1 0.2 0.25 11.1 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat ComX PF05952.7 EGC28318.1 - 0.48 9.9 4.0 10 5.7 0.4 3.7 2 1 1 3 3 3 0 Bacillus competence pheromone ComX XPC-binding PF09280.6 EGC28318.1 - 4.6 6.7 7.3 21 4.6 3.6 2.9 2 1 0 2 2 2 0 XPC-binding domain UQ_con PF00179.21 EGC28319.1 - 2.1e-41 140.6 0.2 2.4e-41 140.4 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme PP2C PF00481.16 EGC28320.1 - 5.9e-73 245.3 0.0 5.9e-73 245.3 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C G-alpha PF00503.15 EGC28320.1 - 4.5e-59 200.0 5.6 4.5e-59 200.0 3.9 2.8 2 1 0 2 2 2 1 G-protein alpha subunit DUF853 PF05872.7 EGC28320.1 - 0.17 10.1 2.7 0.41 8.9 1.9 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Dict-STAT-coil PF09267.5 EGC28321.1 - 4.9e-44 149.1 16.3 4.9e-44 149.1 11.3 4.6 4 2 2 6 6 6 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 EGC28321.1 - 1.6e-11 43.8 0.0 6.7e-11 41.8 0.0 2.2 1 0 0 1 1 1 1 SH2 domain PH_4 PF15404.1 EGC28321.1 - 3.6 7.0 12.5 0.13 11.7 3.9 2.1 2 0 0 2 2 2 0 Pleckstrin homology domain Pkinase PF00069.20 EGC28322.1 - 4.9e-62 209.4 0.2 8.2e-62 208.6 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28322.1 - 1.5e-39 135.6 0.0 2.1e-39 135.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28322.1 - 2.9e-11 42.8 0.0 4.9e-10 38.8 0.0 2.2 2 0 0 2 2 2 1 Kinase-like DUF1179 PF06678.6 EGC28322.1 - 0.052 13.8 0.3 0.1 12.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) DUF1768 PF08719.6 EGC28323.1 - 5.7e-42 143.1 0.0 6.4e-42 142.9 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Sel1 PF08238.7 EGC28324.1 - 7.5e-29 99.5 3.9 4.6e-06 27.0 0.1 7.2 7 0 0 7 7 7 6 Sel1 repeat TPR_11 PF13414.1 EGC28324.1 - 0.0014 18.2 9.9 0.5 10.0 0.1 5.2 4 1 2 6 6 6 3 TPR repeat TPR_2 PF07719.12 EGC28324.1 - 0.43 10.6 9.1 7 6.8 0.1 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC28324.1 - 0.64 9.7 11.0 12 5.6 0.5 5.7 6 0 0 6 6 6 0 Tetratricopeptide repeat Erf4 PF10256.4 EGC28325.1 - 0.1 12.4 0.7 0.13 12.1 0.5 1.1 1 0 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF4600 PF15372.1 EGC28327.1 - 0.057 13.6 1.6 0.058 13.6 1.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4600) DUF479 PF04336.7 EGC28327.1 - 0.063 13.3 0.1 0.74 9.9 0.0 1.9 1 1 1 2 2 2 0 Protein of unknown function, DUF479 U3_assoc_6 PF08640.6 EGC28327.1 - 0.095 12.4 0.7 0.11 12.2 0.5 1.4 1 1 0 1 1 1 0 U3 small nucleolar RNA-associated protein 6 Mitochondr_Som1 PF11093.3 EGC28327.1 - 0.12 12.2 0.8 0.15 11.8 0.5 1.3 1 1 0 1 1 1 0 Mitochondrial export protein Som1 MRG PF05712.8 EGC28328.1 - 1.5e-46 157.7 2.7 2.8e-46 156.8 1.9 1.4 1 0 0 1 1 1 1 MRG Tudor-knot PF11717.3 EGC28328.1 - 4.1e-09 36.0 3.1 8.5e-09 34.9 2.1 1.6 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain PWWP PF00855.12 EGC28328.1 - 0.011 15.9 0.8 0.011 15.9 0.5 2.1 2 0 0 2 2 2 0 PWWP domain DUF3245 PF11595.3 EGC28328.1 - 0.021 15.0 9.3 0.035 14.3 6.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) Macoilin PF09726.4 EGC28328.1 - 0.037 12.3 12.7 0.048 11.9 8.8 1.1 1 0 0 1 1 1 0 Transmembrane protein CDC45 PF02724.9 EGC28328.1 - 0.041 11.9 11.7 0.062 11.3 8.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EGC28328.1 - 3.9 6.5 13.0 6.4 5.8 9.0 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TGS PF02824.16 EGC28331.1 - 3.1e-21 74.9 0.0 5.9e-21 74.0 0.0 1.5 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGC28331.1 - 8.7e-18 64.3 0.1 2.2e-17 63.0 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC28331.1 - 7.1e-11 41.6 0.1 2.3e-10 39.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGC28331.1 - 0.0028 17.4 0.5 1.4 8.7 0.0 2.5 1 1 1 2 2 2 2 Dynamin family GTP_EFTU PF00009.22 EGC28331.1 - 0.0037 16.7 0.6 4.3 6.7 0.0 3.6 2 2 1 3 3 3 2 Elongation factor Tu GTP binding domain Miro PF08477.8 EGC28331.1 - 0.0063 16.9 0.1 0.022 15.2 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein ArgK PF03308.11 EGC28331.1 - 0.0076 15.0 0.5 0.015 14.0 0.1 1.6 2 0 0 2 2 2 1 ArgK protein SRPRB PF09439.5 EGC28331.1 - 0.03 13.5 0.1 0.058 12.5 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1183 PF06682.7 EGC28333.1 - 5.4e-69 233.2 23.1 2.2e-68 231.2 15.8 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1183) MRAP PF15183.1 EGC28333.1 - 0.049 13.2 0.0 0.15 11.6 0.0 1.8 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family Ank_2 PF12796.2 EGC28334.1 - 0.082 13.2 4.4 0.96 9.8 1.9 3.1 2 1 1 3 3 3 0 Ankyrin repeats (3 copies) DUF4382 PF14321.1 EGC28334.1 - 0.37 10.8 5.3 3.8 7.5 0.3 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4382) DDE_3 PF13358.1 EGC28336.1 - 0.033 13.9 0.6 8 6.2 0.0 2.3 2 0 0 2 2 2 0 DDE superfamily endonuclease ATP-synt_E PF05680.7 EGC28336.1 - 0.62 10.0 3.6 0.67 9.9 0.3 2.0 2 0 0 2 2 2 0 ATP synthase E chain PEPcase_2 PF14010.1 EGC28336.1 - 0.96 7.6 6.5 0.99 7.6 4.1 1.3 1 1 0 1 1 1 0 Phosphoenolpyruvate carboxylase A1_Propeptide PF07966.7 EGC28336.1 - 1.5 8.7 4.5 8.1 6.4 0.4 2.5 2 0 0 2 2 2 0 A1 Propeptide UQ_con PF00179.21 EGC28337.1 - 1.8e-46 157.0 0.1 2.4e-46 156.6 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme DUF592 PF04574.8 EGC28337.1 - 0.011 15.3 0.0 0.021 14.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF592) Prok-E2_B PF14461.1 EGC28337.1 - 0.019 14.7 0.0 0.057 13.1 0.0 1.9 1 1 1 2 2 2 0 Prokaryotic E2 family B PD-C2-AF1 PF09310.5 EGC28337.1 - 0.044 12.9 0.0 0.062 12.4 0.0 1.2 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Peptidase_C1 PF00112.18 EGC28338.1 - 1.3e-49 169.0 0.9 1.6e-49 168.7 0.6 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EGC28338.1 - 0.0036 15.8 0.3 0.032 12.7 0.1 2.0 2 0 0 2 2 2 1 Peptidase C1-like family Acyltransferase PF01553.16 EGC28339.1 - 3.6e-13 49.0 0.0 6.7e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase Apc4 PF12896.2 EGC28340.1 - 6.2e-16 58.3 8.0 1.2e-15 57.4 5.5 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 4 WD40 PF00400.27 EGC28340.1 - 0.0018 18.1 0.0 0.0069 16.2 0.1 2.0 2 0 0 2 2 2 1 WD domain, G-beta repeat ATP-synt PF00231.14 EGC28340.1 - 0.014 14.8 1.4 0.044 13.1 0.9 2.0 1 1 0 1 1 1 0 ATP synthase Cyclin PF08613.6 EGC28342.1 - 5.4e-33 114.4 0.2 5.4e-33 114.4 0.1 2.2 3 1 0 3 3 3 1 Cyclin Cyclin_N PF00134.18 EGC28342.1 - 4.8e-13 48.7 1.9 5.6e-13 48.5 0.1 2.1 2 0 0 2 2 2 1 Cyclin, N-terminal domain Lung_7-TM_R PF06814.8 EGC28343.1 - 6.5e-36 123.7 15.9 9.4e-36 123.2 11.1 1.2 1 0 0 1 1 1 1 Lung seven transmembrane receptor SirB PF04247.7 EGC28343.1 - 0.38 10.4 7.9 0.53 10.0 1.7 2.6 2 0 0 2 2 2 0 Invasion gene expression up-regulator, SirB Ham1p_like PF01725.11 EGC28344.1 - 3.9e-40 137.2 0.0 4.7e-40 136.9 0.0 1.0 1 0 0 1 1 1 1 Ham1 family FNIP PF05725.7 EGC28345.1 - 9.6e-19 67.0 38.8 1.6e-05 24.7 0.2 6.3 4 1 1 6 6 6 5 FNIP Repeat AAA_3 PF07726.6 EGC28345.1 - 0.038 13.6 0.1 34 4.0 0.0 3.1 1 1 2 3 3 3 0 ATPase family associated with various cellular activities (AAA) EAF PF09816.4 EGC28345.1 - 0.042 13.8 1.6 30 4.6 0.1 3.7 4 0 0 4 4 4 0 RNA polymerase II transcription elongation factor DUF2523 PF10734.4 EGC28345.1 - 0.057 13.6 0.0 54 4.1 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2523) FNIP PF05725.7 EGC28346.1 - 2.1e-35 120.3 88.5 0.00015 21.6 0.7 14.4 7 3 6 16 16 16 14 FNIP Repeat zf-B_box PF00643.19 EGC28346.1 - 6.3e-05 22.7 6.8 0.00012 21.9 4.7 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF2523 PF10734.4 EGC28346.1 - 0.032 14.4 0.0 34 4.7 0.0 4.8 7 0 0 7 7 7 0 Protein of unknown function (DUF2523) Orbi_VP5 PF00901.12 EGC28346.1 - 8.7 4.4 9.6 13 3.8 6.6 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 Acetyltransf_1 PF00583.19 EGC28347.1 - 1.9e-16 59.8 0.0 2.6e-16 59.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC28347.1 - 5.8e-13 48.8 0.1 9.2e-13 48.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC28347.1 - 1.8e-06 28.0 0.0 2.2e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC28347.1 - 2.9e-05 23.7 0.0 4.7e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_9 PF13527.1 EGC28347.1 - 3.7e-05 23.5 0.0 7.2e-05 22.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC28347.1 - 0.00023 21.3 0.0 0.00027 21.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC28347.1 - 0.00023 21.0 0.0 0.00029 20.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC28347.1 - 0.00063 19.5 0.0 0.0011 18.7 0.0 1.3 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EGC28347.1 - 0.013 15.0 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EGC28347.1 - 0.035 14.0 0.0 0.044 13.7 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Carb_kinase PF01256.12 EGC28347.1 - 0.049 12.9 0.0 0.065 12.5 0.0 1.1 1 0 0 1 1 1 0 Carbohydrate kinase Nup88 PF10168.4 EGC28350.1 - 5.5e-08 31.1 18.8 6.5e-08 30.9 13.0 1.0 1 0 0 1 1 1 1 Nuclear pore component Phage_GPO PF05929.6 EGC28350.1 - 0.1 11.8 5.2 0.17 11.1 2.9 1.7 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase eIF3_N PF09440.5 EGC28350.1 - 0.13 12.3 10.1 0.032 14.3 2.7 2.6 2 1 0 3 3 3 0 eIF3 subunit 6 N terminal domain DUF2730 PF10805.3 EGC28350.1 - 0.73 9.5 5.8 2.1 8.1 0.1 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2730) Sec3_C_2 PF15278.1 EGC28350.1 - 0.87 9.7 9.0 0.36 10.9 0.3 3.4 1 1 4 5 5 5 0 Sec3 exocyst complex subunit DUF1664 PF07889.7 EGC28350.1 - 1.7 8.4 10.6 4.1 7.2 0.9 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) Nup54 PF13874.1 EGC28350.1 - 2.5 7.7 10.4 2.4 7.8 5.8 2.0 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 Prefoldin_3 PF13758.1 EGC28350.1 - 3.7 7.3 12.1 0.28 10.9 3.3 2.6 2 2 0 2 2 2 0 Prefoldin subunit CAF-1_p150 PF11600.3 EGC28351.1 - 0.25 10.7 35.5 0.43 9.9 24.6 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal CopC PF04234.7 EGC28352.1 - 0.13 12.8 0.4 0.23 12.1 0.2 1.5 1 1 1 2 2 2 0 CopC domain LIN37 PF15306.1 EGC28352.1 - 1.9 8.4 14.9 2.3 8.2 10.3 1.1 1 0 0 1 1 1 0 LIN37 DUF1525 PF07511.6 EGC28352.1 - 4.7 7.2 7.9 8.9 6.3 5.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1525) DUF2244 PF10003.4 EGC28352.1 - 9.1 5.6 7.3 3.3 7.0 3.0 1.8 1 1 0 1 1 1 0 Integral membrane protein (DUF2244) Pro-NT_NN PF07421.6 EGC28354.1 - 0.046 13.2 4.2 0.064 12.7 2.7 1.4 1 1 0 1 1 1 0 Neurotensin/neuromedin N precursor Sec5 PF15469.1 EGC28354.1 - 0.15 11.7 7.0 0.47 10.1 1.9 2.4 1 1 1 2 2 2 0 Exocyst complex component Sec5 Beta-Casp PF10996.3 EGC28355.1 - 1.3e-15 57.4 0.0 6e-15 55.2 0.0 2.2 2 0 0 2 2 2 1 Beta-Casp domain Glyco_transf_49 PF13896.1 EGC28356.1 - 6.6e-42 143.7 5.0 1.1e-24 87.1 0.0 3.2 2 1 1 3 3 3 3 Glycosyl-transferase for dystroglycan Glyco_tranf_2_2 PF10111.4 EGC28356.1 - 9.9e-06 24.8 1.1 1.6e-05 24.1 0.7 1.4 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGC28356.1 - 0.026 14.1 0.2 0.071 12.7 0.1 1.9 1 1 0 1 1 1 0 Glycosyl transferase family 2 TRAM_LAG1_CLN8 PF03798.11 EGC28357.1 - 7.8e-22 77.7 27.2 9.5e-22 77.5 18.9 1.1 1 0 0 1 1 1 1 TLC domain GST_C_3 PF14497.1 EGC28358.1 - 2.1e-07 31.3 0.0 3.6e-07 30.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC28358.1 - 1.3e-06 28.5 0.0 5.5e-06 26.5 0.0 2.0 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC28358.1 - 0.00025 20.8 0.0 0.00052 19.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC28358.1 - 0.00031 20.6 0.0 0.00084 19.2 0.0 1.8 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC28358.1 - 0.024 14.5 0.0 0.058 13.3 0.0 1.7 2 0 0 2 2 2 0 Glutathione S-transferase, C-terminal domain zf-RING_2 PF13639.1 EGC28359.1 - 9.6e-09 34.9 7.9 1.3e-08 34.5 5.4 1.2 1 0 0 1 1 1 1 Ring finger domain Prok-RING_1 PF14446.1 EGC28359.1 - 0.00033 20.3 5.6 0.00051 19.7 1.8 2.0 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 PHD PF00628.24 EGC28359.1 - 0.00094 18.8 8.4 0.0016 18.0 5.8 1.4 1 0 0 1 1 1 1 PHD-finger zf-C3HC4_3 PF13920.1 EGC28359.1 - 0.0012 18.4 5.1 0.0018 17.9 3.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Sec23_Sec24 PF04810.10 EGC28359.1 - 0.0019 17.7 5.6 0.2 11.2 0.1 3.2 3 0 0 3 3 3 2 Sec23/Sec24 zinc finger zf-Apc11 PF12861.2 EGC28359.1 - 0.01 15.6 7.6 0.022 14.6 5.3 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_1 PF00130.17 EGC28359.1 - 0.011 15.4 2.6 0.011 15.4 1.8 1.7 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-rbx1 PF12678.2 EGC28359.1 - 0.013 15.5 9.6 0.028 14.5 6.7 1.5 1 1 0 1 1 1 0 RING-H2 zinc finger Tnp_zf-ribbon_2 PF13842.1 EGC28359.1 - 0.016 15.5 1.2 0.037 14.4 0.1 2.1 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon zf-C3HC4_2 PF13923.1 EGC28359.1 - 0.039 13.9 8.4 0.063 13.3 5.8 1.4 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Thioredoxin_2 PF13098.1 EGC28359.1 - 0.075 13.2 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain zf-C3HC4 PF00097.20 EGC28359.1 - 0.11 12.1 6.5 0.24 11.0 4.5 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGC28359.1 - 0.25 11.4 9.2 0.44 10.6 6.4 1.5 1 0 0 1 1 1 0 RING-variant domain SR-25 PF10500.4 EGC28359.1 - 0.32 10.4 4.5 0.38 10.1 3.1 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein zf-MIZ PF02891.15 EGC28359.1 - 0.56 9.7 11.3 0.13 11.7 1.1 2.8 2 1 1 3 3 3 0 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EGC28359.1 - 1.2 8.9 5.2 3.1 7.5 3.6 1.8 1 1 0 1 1 1 0 zinc-RING finger domain FANCL_C PF11793.3 EGC28359.1 - 1.6 8.7 8.9 4.5 7.3 6.2 1.7 1 1 0 1 1 1 0 FANCL C-terminal domain zf-4CXXC_R1 PF10497.4 EGC28359.1 - 2.8 8.1 6.7 7.7 6.7 0.6 2.4 1 1 1 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 Cytochrome_C7 PF14522.1 EGC28359.1 - 7.7 6.2 7.5 4.3 7.0 1.9 2.2 1 1 1 2 2 2 0 Cytochrome c7 Ank_2 PF12796.2 EGC28360.1 - 4.7e-36 123.0 0.6 4.5e-17 62.1 0.0 2.6 1 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC28360.1 - 1.1e-34 116.4 0.1 2.3e-08 33.4 0.0 5.5 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EGC28360.1 - 1e-31 108.6 0.6 3.4e-13 49.6 0.0 5.0 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC28360.1 - 2.2e-26 89.2 1.8 2.1e-06 27.4 0.1 6.2 6 0 0 6 6 6 4 Ankyrin repeat Ank_5 PF13857.1 EGC28360.1 - 2.3e-22 78.4 0.5 1.4e-07 31.4 0.0 4.8 2 2 2 4 4 4 4 Ankyrin repeats (many copies) PH PF00169.24 EGC28360.1 - 9.7e-09 35.3 1.5 1.4e-08 34.9 0.1 2.0 2 0 0 2 2 2 1 PH domain Tetraspannin PF00335.15 EGC28362.1 - 0.061 12.6 2.0 0.25 10.5 1.4 1.9 1 1 0 1 1 1 0 Tetraspanin family UPF0506 PF11703.3 EGC28363.1 - 0.025 14.5 9.1 0.025 14.5 6.3 6.0 4 2 3 7 7 7 0 UPF0506 Toxin_11 PF07473.6 EGC28363.1 - 6.6 6.7 12.6 0.37 10.7 0.3 4.2 3 0 0 3 3 3 0 Spasmodic peptide gm9a NAD_binding_6 PF08030.7 EGC28364.1 - 1.8e-25 89.6 0.0 1.8e-25 89.6 0.0 1.9 2 0 0 2 2 2 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGC28364.1 - 4.1e-24 84.4 0.1 8.9e-24 83.3 0.0 1.6 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGC28364.1 - 2.1e-18 66.6 8.1 4.1e-18 65.6 5.6 1.4 1 0 0 1 1 1 1 Ferric reductase like transmembrane component EF-hand_1 PF00036.27 EGC28364.1 - 1.6e-08 33.2 5.0 5.5e-06 25.2 1.7 2.7 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EGC28364.1 - 1.7e-08 33.6 7.6 0.00014 21.4 1.5 3.5 3 0 0 3 3 3 2 EF-hand domain EF-hand_7 PF13499.1 EGC28364.1 - 3.6e-08 33.4 3.2 1e-07 31.9 2.2 1.8 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EGC28364.1 - 2.4e-07 29.7 4.0 5.5e-06 25.4 1.6 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGC28364.1 - 1.7e-05 24.3 3.1 4.7e-05 22.9 1.4 2.1 1 1 1 2 2 2 2 EF-hand domain pair FAD_binding_6 PF00970.19 EGC28364.1 - 6.2e-05 23.0 0.0 0.00014 21.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGC28364.1 - 0.0012 19.3 0.4 0.17 12.4 0.0 3.1 3 0 0 3 3 3 1 Oxidoreductase NAD-binding domain LRRC37AB_C PF14914.1 EGC28364.1 - 1.3 8.4 4.7 6.6 6.1 0.1 2.5 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain DUF605 PF04652.11 EGC28365.1 - 5.1 6.3 20.6 7.9 5.7 14.3 1.4 1 0 0 1 1 1 0 Vta1 like Peptidase_S28 PF05577.7 EGC28366.1 - 3.8e-74 249.8 4.0 3.8e-74 249.8 2.8 1.3 2 0 0 2 2 2 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 EGC28366.1 - 5.3e-08 32.7 0.0 8e-08 32.1 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC28366.1 - 9.8e-05 22.3 0.0 0.00017 21.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC28366.1 - 0.018 14.7 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family RWD PF05773.17 EGC28367.1 - 2e-20 72.8 2.2 4.2e-20 71.7 1.5 1.6 1 0 0 1 1 1 1 RWD domain IBR PF01485.16 EGC28367.1 - 6.5e-14 51.5 52.6 5.3e-06 26.2 6.3 5.1 3 1 1 4 4 4 3 IBR domain zf-C3HC4 PF00097.20 EGC28367.1 - 0.014 15.0 8.8 0.014 15.0 6.1 5.0 4 1 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) SpoIIIAH PF12685.2 EGC28368.1 - 0.0072 15.8 5.8 0.0072 15.8 4.0 2.0 2 0 0 2 2 2 1 SpoIIIAH-like protein Zip PF02535.17 EGC28368.1 - 0.085 11.8 8.7 10 5.0 6.1 2.1 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1212 PF06738.7 EGC28368.1 - 1.1 8.6 2.7 1.6 8.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) UPF0160 PF03690.8 EGC28369.1 - 3.9e-127 424.0 0.0 4.4e-127 423.8 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0160) RRF PF01765.14 EGC28370.1 - 2.6e-48 163.5 1.1 3.5e-48 163.1 0.7 1.2 1 0 0 1 1 1 1 Ribosome recycling factor DinI PF06183.8 EGC28370.1 - 0.14 12.1 0.4 0.29 11.1 0.3 1.5 1 0 0 1 1 1 0 DinI-like family PUCC PF03209.10 EGC28371.1 - 0.00078 18.2 5.0 0.00096 17.9 3.5 1.1 1 0 0 1 1 1 1 PUCC protein Spore_YhaL PF14147.1 EGC28371.1 - 1.5 8.2 4.0 4.9 6.6 0.0 2.7 2 0 0 2 2 2 0 Sporulation protein YhaL Erf4 PF10256.4 EGC28372.1 - 0.00033 20.5 4.0 0.00033 20.5 2.8 2.1 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Sec7_N PF12783.2 EGC28372.1 - 0.00075 18.9 2.7 0.00097 18.6 1.4 1.4 1 1 0 1 1 1 1 Guanine nucleotide exchange factor in Golgi transport N-terminal MRAP PF15183.1 EGC28372.1 - 0.061 12.9 0.9 0.18 11.3 0.6 1.9 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family DUF2852 PF11014.3 EGC28372.1 - 0.25 11.2 0.1 0.25 11.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2852) PTPA PF03095.10 EGC28373.1 - 5.8e-99 331.0 2.8 7e-94 314.3 0.6 2.0 1 1 1 2 2 2 2 Phosphotyrosyl phosphate activator (PTPA) protein MutS_II PF05188.12 EGC28373.1 - 0.073 13.1 0.0 11 6.1 0.0 2.3 1 1 1 2 2 2 0 MutS domain II HmuY PF14064.1 EGC28375.1 - 0.041 13.8 0.2 0.043 13.7 0.1 1.1 1 0 0 1 1 1 0 HmuY protein PARP PF00644.15 EGC28377.1 - 1.9e-09 37.2 0.1 2.7e-09 36.7 0.1 1.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain Ank_2 PF12796.2 EGC28378.1 - 1.4e-18 66.9 0.0 8e-09 35.7 0.0 4.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC28378.1 - 7.5e-16 57.0 0.1 3.7e-07 29.6 0.1 3.9 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGC28378.1 - 5.6e-12 45.8 2.7 4.6e-06 26.9 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC28378.1 - 8.8e-12 44.0 0.5 1.9e-05 24.4 0.1 4.3 5 0 0 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EGC28378.1 - 3.1e-10 39.9 0.0 2.9e-06 27.3 0.0 6.6 4 2 1 5 5 5 2 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.1 EGC28378.1 - 5.7e-06 25.9 8.8 8.8e-06 25.3 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) FNIP PF05725.7 EGC28380.1 - 1.7e-55 184.7 48.4 2.3e-11 43.4 2.5 9.1 2 2 7 10 10 10 10 FNIP Repeat LRR_5 PF13306.1 EGC28380.1 - 0.11 12.1 13.1 0.1 12.3 0.3 3.9 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) DUF2874 PF11396.3 EGC28382.1 - 0.12 12.3 3.2 0.21 11.5 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2874) zf-C3HC4_3 PF13920.1 EGC28383.1 - 2e-07 30.5 4.1 3.2e-07 29.8 2.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28383.1 - 1.1e-05 24.9 12.0 0.00021 20.9 8.2 2.4 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28383.1 - 1.2e-05 25.2 12.3 0.00037 20.4 8.6 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC28383.1 - 1.8e-05 24.3 8.5 3.6e-05 23.3 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC28383.1 - 0.0003 20.5 9.4 0.0013 18.4 6.5 2.0 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC28383.1 - 0.00061 19.8 2.9 0.0011 19.0 2.0 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGC28383.1 - 0.0094 15.4 4.4 0.021 14.3 3.0 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGC28383.1 - 0.015 15.0 2.4 0.03 14.0 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC28383.1 - 0.02 14.7 6.5 0.02 14.7 4.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SurA_N_2 PF13623.1 EGC28383.1 - 0.096 12.6 0.1 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain Oxidored_q1_N PF00662.15 EGC28383.1 - 0.14 11.7 2.2 0.24 10.9 1.5 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus DUF221 PF02714.10 EGC28383.1 - 0.19 10.5 1.7 0.31 9.8 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF221 Coleoptericin PF06286.6 EGC28383.1 - 0.22 11.3 2.3 0.72 9.7 1.6 1.8 1 1 0 1 1 1 0 Coleoptericin zf-RING_4 PF14570.1 EGC28383.1 - 0.26 10.8 8.3 0.53 9.9 5.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF2393 PF09624.5 EGC28383.1 - 2.2 7.7 7.0 0.51 9.8 2.3 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) zf-RING_3 PF14369.1 EGC28383.1 - 3.7 7.6 7.6 14 5.7 3.0 2.6 2 1 0 2 2 2 0 zinc-finger zf-CCCH PF00642.19 EGC28384.1 - 3.2e-12 45.8 21.4 2.9e-06 26.8 0.7 3.7 4 0 0 4 4 4 3 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RING_2 PF13639.1 EGC28384.1 - 9e-11 41.4 3.7 9e-11 41.4 2.6 2.6 3 1 0 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EGC28384.1 - 1.7e-06 27.6 3.2 1.7e-06 27.6 2.2 2.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC28384.1 - 1.7e-06 27.5 2.5 1.7e-06 27.5 1.7 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28384.1 - 0.00011 22.1 4.4 0.00011 22.1 3.0 2.5 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC28384.1 - 0.003 17.3 2.0 0.003 17.3 1.4 3.4 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGC28384.1 - 0.0044 16.9 3.3 0.021 14.8 2.3 2.2 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_6 PF14835.1 EGC28384.1 - 0.015 15.0 0.8 0.058 13.1 0.5 2.0 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_RING PF05883.6 EGC28384.1 - 0.03 14.1 1.5 0.072 12.9 1.0 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain TAXi_C PF14541.1 EGC28384.1 - 0.077 12.5 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 Xylanase inhibitor C-terminal zf-rbx1 PF12678.2 EGC28384.1 - 0.56 10.3 18.9 0.63 10.1 10.5 2.9 2 1 0 2 2 2 0 RING-H2 zinc finger zf-CCCH_2 PF14608.1 EGC28384.1 - 1.8 8.6 31.7 0.28 11.2 2.1 4.6 4 1 0 4 4 3 0 Zinc finger C-x8-C-x5-C-x3-H type Macoilin PF09726.4 EGC28384.1 - 2.9 6.0 8.7 4.3 5.4 6.0 1.2 1 0 0 1 1 1 0 Transmembrane protein zf-C3H1 PF10650.4 EGC28384.1 - 6.8 6.2 10.8 0.43 10.1 0.6 3.7 4 0 0 4 4 4 0 Putative zinc-finger domain BAG PF02179.11 EGC28385.1 - 1.5e-08 34.6 6.8 0.0046 17.0 3.9 2.5 2 0 0 2 2 2 2 BAG domain TMF_TATA_bd PF12325.3 EGC28385.1 - 1.7 8.4 14.0 0.95 9.2 2.1 2.7 3 0 0 3 3 3 0 TATA element modulatory factor 1 TATA binding LOH1CR12 PF10158.4 EGC28385.1 - 7.6 6.3 10.0 0.17 11.7 0.9 2.4 2 1 1 3 3 3 0 Tumour suppressor protein Myb_DNA-bind_6 PF13921.1 EGC28386.1 - 2.9e-30 104.1 7.9 8e-15 54.6 0.3 3.9 3 1 1 4 4 4 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGC28386.1 - 1.4e-29 101.8 11.4 1.8e-14 53.5 1.1 3.5 3 1 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGC28386.1 - 0.001 19.1 1.8 0.001 19.1 1.3 4.2 3 1 1 4 4 4 2 Myb/SANT-like DNA-binding domain Myb_DNA-bind_5 PF13873.1 EGC28386.1 - 0.26 11.2 11.9 1.5 8.7 1.0 4.2 2 2 1 4 4 4 0 Myb/SANT-like DNA-binding domain DUF3440 PF11922.3 EGC28386.1 - 1.5 8.3 7.5 0.7 9.4 0.7 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF3440) PIN PF01850.16 EGC28387.1 - 0.25 11.6 6.6 0.09 13.1 2.5 1.9 1 1 1 2 2 2 0 PIN domain Pyr_redox PF00070.22 EGC28387.1 - 1.2 9.6 8.5 9.5 6.7 0.5 2.6 1 1 1 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Reo_sigmaC PF04582.7 EGC28387.1 - 2.8 7.0 4.7 2.2 7.3 0.5 2.2 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Tox-GHH PF15636.1 EGC28390.1 - 0.013 15.1 3.4 0.013 15.1 2.4 1.6 2 0 0 2 2 2 0 GHH signature containing HNH/Endo VII superfamily nuclease toxin DUF4050 PF13259.1 EGC28390.1 - 0.19 11.6 6.3 0.25 11.2 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4050) YjgP_YjgQ PF03739.9 EGC28390.1 - 0.42 9.2 10.6 0.52 9.0 7.3 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1900 PF08954.6 EGC28390.1 - 0.51 9.8 5.9 3.3 7.2 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1900) vATP-synt_E PF01991.13 EGC28390.1 - 0.56 9.4 17.4 0.74 9.0 12.0 1.1 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit MRP-S32 PF10210.4 EGC28390.1 - 3.8 7.8 6.6 6.8 7.0 4.6 1.4 1 1 0 1 1 1 0 Mitochondrial 28S ribosomal protein S32 OTU PF02338.14 EGC28391.1 - 7.1e-12 45.9 0.1 8.7e-12 45.6 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease ECSIT PF06239.6 EGC28391.1 - 0.1 11.4 0.0 0.19 10.5 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway OTU PF02338.14 EGC28392.1 - 1e-10 42.2 0.1 2e-10 41.3 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease PAT1 PF09770.4 EGC28392.1 - 0.76 7.9 27.7 1 7.5 19.2 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Secretin_N_2 PF07655.8 EGC28394.1 - 0.14 12.5 5.1 0.12 12.7 3.5 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain OATP PF03137.15 EGC28394.1 - 0.16 9.9 1.7 0.16 9.9 1.2 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family OTU PF02338.14 EGC28395.1 - 1.6e-13 51.2 0.0 3.1e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease TFIIA PF03153.8 EGC28395.1 - 1.1 9.0 26.9 1.5 8.6 18.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EF-hand_1 PF00036.27 EGC28396.1 - 6.1e-17 59.5 6.9 0.00023 20.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC28396.1 - 6.9e-17 61.3 11.1 3.2e-09 36.7 1.4 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC28396.1 - 2e-14 52.0 6.6 0.0022 17.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC28396.1 - 3.1e-07 29.4 3.3 0.036 13.3 0.1 4.5 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EGC28396.1 - 1.4e-05 25.0 0.9 0.0049 16.8 0.1 2.4 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 EGC28396.1 - 0.0024 17.4 5.5 0.55 9.9 0.3 3.8 3 1 0 3 3 3 2 EF-hand domain pair Dimer_Tnp_hAT PF05699.9 EGC28397.1 - 7e-16 57.6 0.5 8.7e-16 57.3 0.4 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF4300 PF14133.1 EGC28397.1 - 0.049 12.8 0.3 0.054 12.7 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) Kelch_6 PF13964.1 EGC28398.1 - 0.082 13.1 0.1 0.35 11.1 0.1 2.1 1 0 0 1 1 1 0 Kelch motif DUF1084 PF06454.6 EGC28402.1 - 6.1e-15 55.0 19.1 8e-15 54.6 13.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) Orbi_NS3 PF01616.11 EGC28402.1 - 0.45 9.4 4.5 0.28 10.1 0.1 2.3 2 1 1 3 3 3 0 Orbivirus NS3 DUF2909 PF11137.3 EGC28402.1 - 1.4 8.6 5.8 1.7 8.4 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2909) DUF2919 PF11143.3 EGC28402.1 - 4.5 7.0 17.6 3.1 7.6 3.0 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2919) Oxysterol_BP PF01237.13 EGC28403.1 - 3e-49 167.4 4.6 4.6e-49 166.7 3.2 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein Phage_tail PF04630.7 EGC28405.1 - 0.042 12.9 0.2 0.047 12.7 0.1 1.1 1 0 0 1 1 1 0 Phage major tail protein GDE_C PF06202.9 EGC28405.1 - 0.054 12.2 0.0 0.056 12.1 0.0 1.0 1 0 0 1 1 1 0 Amylo-alpha-1,6-glucosidase Pkinase PF00069.20 EGC28406.1 - 1.3e-44 152.3 4.3 4.7e-19 68.5 0.3 4.3 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28406.1 - 1.1e-30 106.5 0.1 3.7e-14 52.4 0.1 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase TFIIA PF03153.8 EGC28406.1 - 0.0017 18.3 20.4 0.0017 18.3 14.1 2.9 3 0 0 3 3 3 1 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 EGC28406.1 - 0.45 9.6 26.6 0.0091 15.2 11.3 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Daxx PF03344.10 EGC28406.1 - 2.6 6.4 52.6 0.025 13.0 22.4 2.2 2 0 0 2 2 2 0 Daxx Family RRM_2 PF04059.7 EGC28407.1 - 1.4e-25 89.0 0.4 1.6e-25 88.9 0.3 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EGC28407.1 - 9.1e-05 22.3 0.0 0.00012 21.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC28407.1 - 0.0031 17.1 0.0 0.0041 16.7 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) LRR_4 PF12799.2 EGC28408.1 - 3.9e-29 99.7 55.8 2.9e-09 36.3 8.0 6.0 1 1 5 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC28408.1 - 9.9e-28 95.6 53.2 8.8e-09 34.9 8.0 4.2 2 2 3 5 5 5 5 Leucine rich repeat LRR_1 PF00560.28 EGC28408.1 - 5.2e-18 62.3 23.0 0.016 15.1 0.2 8.2 8 0 0 8 8 8 7 Leucine Rich Repeat LRR_7 PF13504.1 EGC28408.1 - 1.4e-10 39.5 21.4 0.13 12.5 0.7 7.5 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EGC28408.1 - 0.00021 21.0 24.2 4.6 7.6 0.1 7.3 7 1 0 7 7 7 4 Leucine Rich repeat DUF3439 PF11921.3 EGC28408.1 - 0.034 13.8 1.6 0.06 13.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) NOG1 PF06858.9 EGC28408.1 - 0.1 12.4 0.1 0.25 11.2 0.0 1.6 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) FNIP PF05725.7 EGC28409.1 - 6.6e-96 314.0 47.0 9.5e-11 41.4 0.1 11.6 4 2 5 13 13 13 13 FNIP Repeat LRR_5 PF13306.1 EGC28409.1 - 2.8e-12 46.4 2.3 6.5e-05 22.6 0.0 4.8 3 2 0 3 3 3 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC28409.1 - 0.0066 16.3 8.9 37 4.3 0.2 6.6 6 2 2 8 8 8 0 Protein of unknown function (DUF1769) DUF717 PF05338.7 EGC28409.1 - 0.7 9.8 6.3 74 3.4 0.0 5.6 7 0 0 7 7 7 0 Protein of unknown function (DUF717) DUF2874 PF11396.3 EGC28410.1 - 0.037 13.9 1.3 0.051 13.5 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2874) Bromodomain PF00439.20 EGC28414.1 - 2.4e-09 36.9 0.4 6.1e-09 35.6 0.3 1.7 1 0 0 1 1 1 1 Bromodomain Med11 PF10280.4 EGC28414.1 - 0.027 14.4 3.2 0.039 13.9 2.2 1.3 1 0 0 1 1 1 0 Mediator complex protein FadA PF09403.5 EGC28414.1 - 0.032 14.2 5.2 0.1 12.6 1.1 2.1 2 0 0 2 2 2 0 Adhesion protein FadA GSCFA PF08885.6 EGC28414.1 - 0.035 13.6 0.1 0.066 12.7 0.1 1.4 1 0 0 1 1 1 0 GSCFA family Spuma_A9PTase PF03539.9 EGC28414.1 - 0.061 13.2 0.5 0.12 12.2 0.1 1.6 2 0 0 2 2 2 0 Spumavirus aspartic protease (A9) Ammonium_transp PF00909.16 EGC28420.1 - 2.9e-112 375.0 24.6 3.4e-112 374.8 17.0 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Zip PF02535.17 EGC28421.1 - 0.12 11.4 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Methyltransf_4 PF02390.12 EGC28423.1 - 2.1e-21 75.9 9.7 2.9e-21 75.4 4.1 2.4 1 1 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGC28423.1 - 2.1e-05 25.0 0.0 3.5e-05 24.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC28423.1 - 0.00031 20.3 4.2 0.00047 19.7 2.1 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC28423.1 - 0.0085 16.4 0.0 0.023 15.0 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC28423.1 - 0.034 13.8 0.0 0.063 13.0 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain Acetyltransf_4 PF13420.1 EGC28423.1 - 0.038 13.9 2.5 0.082 12.8 1.7 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Methyltransf_12 PF08242.7 EGC28423.1 - 0.05 14.0 10.5 0.05 14.0 3.0 3.3 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC28423.1 - 0.059 13.8 0.0 0.17 12.4 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain HD_3 PF13023.1 EGC28423.1 - 0.084 12.6 0.2 0.21 11.2 0.0 1.6 2 0 0 2 2 2 0 HD domain DUF1390 PF07150.6 EGC28423.1 - 2.5 7.4 13.7 0.21 10.9 5.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) AMP-binding PF00501.23 EGC28424.1 - 9.3e-76 254.8 0.0 1.1e-75 254.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC28424.1 - 1e-11 45.5 0.0 2.4e-11 44.4 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1528 PF07515.6 EGC28424.1 - 0.015 15.2 0.4 2.3 8.2 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1528) TruB_N PF01509.13 EGC28425.1 - 1.2e-40 139.0 0.2 2.1e-40 138.2 0.2 1.4 1 0 0 1 1 1 1 TruB family pseudouridylate synthase (N terminal domain) Clat_adaptor_s PF01217.15 EGC28426.1 - 7.7e-21 74.2 3.5 1e-20 73.8 2.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Ras PF00071.17 EGC28427.1 - 2.5e-60 202.5 0.1 2.9e-60 202.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28427.1 - 4.4e-19 69.1 0.0 8.3e-19 68.2 0.0 1.4 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC28427.1 - 5.1e-11 42.1 0.1 6.4e-11 41.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC28427.1 - 1.6e-05 24.1 0.0 2e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC28427.1 - 6.1e-05 22.5 0.0 0.00011 21.6 0.0 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC28427.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC28427.1 - 0.0071 15.6 0.1 0.047 12.9 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF1537 PF07005.6 EGC28427.1 - 0.028 14.0 0.1 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 SAYSvFN PF10260.4 EGC28428.1 - 2.9e-18 65.4 0.9 4.2e-18 64.8 0.6 1.2 1 0 0 1 1 1 1 Uncharacterized conserved domain (SAYSvFN) FUSC_2 PF13515.1 EGC28428.1 - 0.017 15.0 0.3 0.023 14.5 0.2 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Aminotran_5 PF00266.14 EGC28429.1 - 4.5e-32 111.2 0.0 1.2e-31 109.8 0.0 1.7 1 1 0 1 1 1 1 Aminotransferase class-V MOSC_N PF03476.11 EGC28429.1 - 1.1e-21 76.6 0.0 2.2e-21 75.8 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGC28429.1 - 2.3e-13 49.7 0.0 2.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 MOSC domain DUF4492 PF14899.1 EGC28429.1 - 0.15 11.5 2.5 0.49 9.9 1.7 2.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4492) DUF3139 PF11337.3 EGC28429.1 - 1.7 8.9 6.1 0.3 11.3 0.7 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Pkinase PF00069.20 EGC28431.1 - 9.9e-13 47.8 0.0 1.1e-12 47.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28431.1 - 1.4e-10 40.7 0.0 1.4e-10 40.6 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC28431.1 - 0.00012 21.2 0.0 0.00012 21.2 0.0 1.0 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC28431.1 - 0.0043 16.4 0.1 0.0049 16.2 0.0 1.2 1 0 0 1 1 1 1 RIO1 family Choline_kinase PF01633.15 EGC28431.1 - 0.069 12.7 0.4 0.081 12.4 0.3 1.2 1 0 0 1 1 1 0 Choline/ethanolamine kinase APH PF01636.18 EGC28431.1 - 0.12 12.0 0.0 3.5 7.2 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family FNIP PF05725.7 EGC28432.1 - 1.8e-35 120.5 53.0 4.2e-11 42.6 1.5 8.3 4 2 4 9 9 9 8 FNIP Repeat Scm3 PF10384.4 EGC28434.1 - 0.0075 15.7 0.2 0.019 14.4 0.1 1.7 1 0 0 1 1 1 1 Centromere protein Scm3 DUF2597 PF10772.4 EGC28434.1 - 0.011 15.6 1.3 0.019 14.8 0.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2597) OTU PF02338.14 EGC28436.1 - 1.6e-11 44.8 0.1 1.9e-11 44.6 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Omp28 PF11551.3 EGC28436.1 - 0.05 13.1 0.0 0.064 12.7 0.0 1.2 1 0 0 1 1 1 0 Outer membrane protein Omp28 U-box PF04564.10 EGC28436.1 - 0.15 12.0 0.2 7.1 6.6 0.0 2.3 2 0 0 2 2 2 0 U-box domain EF-hand_1 PF00036.27 EGC28438.1 - 8.6e-24 80.9 4.7 6.4e-05 21.9 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC28438.1 - 1.4e-22 79.5 3.3 1.5e-12 47.4 0.0 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC28438.1 - 2.6e-18 64.1 1.6 0.00087 18.9 0.0 4.3 3 1 1 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC28438.1 - 5.4e-14 50.7 1.7 2.5e-05 23.4 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGC28438.1 - 1e-13 50.6 2.3 1.3e-05 24.7 0.1 4.1 2 2 2 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC28438.1 - 4.2e-09 36.4 1.8 0.0011 18.9 0.1 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGC28438.1 - 0.0032 17.3 0.2 0.26 11.2 0.0 2.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_10 PF14788.1 EGC28438.1 - 0.0038 16.8 2.4 0.073 12.7 0.1 2.9 2 1 1 3 3 3 1 EF hand Aspzincin_M35 PF14521.1 EGC28438.1 - 0.059 13.8 2.8 0.07 13.6 0.3 1.9 1 1 1 2 2 2 0 Lysine-specific metallo-endopeptidase SPK PF04435.13 EGC28438.1 - 0.17 11.8 1.9 9.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF545) DUF2458 PF10454.4 EGC28438.1 - 0.23 11.3 5.3 4.1 7.2 3.7 2.2 1 1 0 1 1 1 0 Protein of unknown function (DUF2458) Trehalase_Ca-bi PF07492.6 EGC28438.1 - 0.27 10.6 5.2 6 6.2 0.1 3.8 4 0 0 4 4 4 0 Neutral trehalase Ca2+ binding domain Sugar_tr PF00083.19 EGC28439.1 - 5e-40 137.4 26.7 4.6e-38 130.9 18.5 2.0 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGC28439.1 - 2.7e-35 121.7 42.8 6.3e-30 104.0 18.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGC28439.1 - 6.8e-10 37.9 16.6 7.8e-06 24.5 3.7 3.2 2 1 1 3 3 3 3 MFS/sugar transport protein UCR_6-4kD PF08997.5 EGC28439.1 - 6.9 6.4 7.6 83 3.0 0.0 4.0 4 0 0 4 4 4 0 Ubiquinol-cytochrome C reductase complex, 6.4kD protein Peptidase_C1 PF00112.18 EGC28440.1 - 1e-59 202.0 4.3 1.2e-59 201.8 3.0 1.0 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EGC28440.1 - 1.3e-06 27.2 1.3 0.0023 16.5 0.1 2.1 2 0 0 2 2 2 2 Peptidase C1-like family Sod_Cu PF00080.15 EGC28441.1 - 8.6e-34 116.7 0.1 3.7e-23 82.2 1.0 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) EIF_2_alpha PF07541.7 EGC28442.1 - 3.6e-35 120.1 0.0 8.3e-35 118.9 0.0 1.6 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 2 alpha subunit Porin_3 PF01459.17 EGC28442.1 - 5.4e-18 65.2 9.6 7.1e-18 64.8 6.6 1.1 1 0 0 1 1 1 1 Eukaryotic porin S1 PF00575.18 EGC28442.1 - 3.1e-15 56.0 1.5 9e-15 54.5 1.0 1.9 1 0 0 1 1 1 1 S1 RNA binding domain PBP1_TM PF14812.1 EGC28442.1 - 0.72 10.1 4.5 1.6 9.1 3.1 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PKI PF02827.11 EGC28442.1 - 1.2 9.3 4.7 2.4 8.3 3.3 1.5 1 0 0 1 1 1 0 cAMP-dependent protein kinase inhibitor DUF605 PF04652.11 EGC28444.1 - 0.0036 16.7 24.2 0.0047 16.3 16.8 1.1 1 0 0 1 1 1 1 Vta1 like Rrn6 PF10214.4 EGC28444.1 - 0.08 11.0 15.7 0.092 10.8 10.9 1.1 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor DUF4145 PF13643.1 EGC28444.1 - 0.086 12.7 0.2 0.16 11.8 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) Hid1 PF12722.2 EGC28444.1 - 0.13 9.9 16.8 0.16 9.6 11.6 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF2413 PF10310.4 EGC28444.1 - 0.25 10.1 19.1 0.33 9.7 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PAT1 PF09770.4 EGC28444.1 - 0.47 8.6 43.5 0.71 8.0 30.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGC28444.1 - 0.64 9.8 25.8 0.81 9.5 17.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RR_TM4-6 PF06459.7 EGC28444.1 - 0.82 9.5 13.7 1.3 8.8 9.5 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Spc7_N PF15402.1 EGC28444.1 - 0.95 7.3 18.3 1.2 7.0 12.7 1.0 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 GAGA_bind PF06217.7 EGC28444.1 - 1.4 8.8 17.8 1.8 8.4 12.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Kei1 PF08552.6 EGC28444.1 - 4 7.0 9.4 0.12 11.9 1.6 2.0 2 1 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 SprA-related PF12118.3 EGC28444.1 - 6.3 6.0 31.8 8.1 5.6 22.0 1.1 1 0 0 1 1 1 0 SprA-related family DUF4613 PF15390.1 EGC28444.1 - 7.7 4.5 11.1 9.5 4.2 7.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4613) UPF0697 PF15117.1 EGC28446.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 FNIP PF05725.7 EGC28447.1 - 1.2e-191 620.4 80.5 1.5e-15 56.8 0.1 12.1 3 2 13 17 17 17 17 FNIP Repeat Phage_min_tail PF05939.8 EGC28447.1 - 1.7e-08 34.3 0.0 26 4.8 0.0 8.9 3 2 6 10 10 10 1 Phage minor tail protein Bclx_interact PF08945.5 EGC28447.1 - 6.1 6.4 6.5 1.3e+02 2.1 0.0 5.0 6 0 0 6 6 6 0 Bcl-x interacting, BH3 domain 2-Hacid_dh_C PF02826.14 EGC28448.1 - 5e-58 195.1 0.0 9e-58 194.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC28448.1 - 3e-21 75.2 0.0 4.3e-21 74.7 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC28448.1 - 0.00013 21.9 0.0 0.0003 20.6 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase NLE PF08154.7 EGC28448.1 - 0.25 11.3 2.2 0.42 10.6 0.2 2.3 3 0 0 3 3 3 0 NLE (NUC135) domain PI3_PI4_kinase PF00454.22 EGC28449.1 - 7.3e-35 120.5 0.2 7.3e-35 120.5 0.1 3.3 4 1 0 4 4 4 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGC28449.1 - 0.0013 17.9 0.1 0.0034 16.5 0.1 1.7 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) Pkinase PF00069.20 EGC28450.1 - 5.3e-27 94.6 19.0 2.2e-17 63.0 1.2 5.0 2 1 3 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28450.1 - 2.3e-13 49.8 0.1 1.1e-05 24.6 0.0 3.4 2 1 1 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 EGC28450.1 - 0.011 14.7 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tctex-1 PF03645.8 EGC28450.1 - 0.14 11.9 16.4 0.079 12.8 0.5 4.5 4 0 0 4 4 4 0 Tctex-1 family APH PF01636.18 EGC28450.1 - 1.2 8.7 0.0 1.9 8.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family CKAP2_C PF15297.1 EGC28451.1 - 0.023 13.5 3.7 0.029 13.1 2.6 1.1 1 0 0 1 1 1 0 Cytoskeleton-associated protein 2 C-terminus DUF3361 PF11841.3 EGC28454.1 - 0.9 9.2 10.2 0.083 12.6 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3361) DUF3439 PF11921.3 EGC28454.1 - 4.6 7.0 8.9 8.6 6.1 6.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RIH_assoc PF08454.6 EGC28454.1 - 5.6 6.6 10.2 0.19 11.3 1.9 2.5 2 2 0 2 2 2 0 RyR and IP3R Homology associated ATP_transf PF09830.4 EGC28455.1 - 3e-22 78.1 0.0 5.7e-22 77.2 0.0 1.5 1 0 0 1 1 1 1 ATP adenylyltransferase FNIP PF05725.7 EGC28456.1 - 1.2e-38 130.7 37.5 1e-09 38.2 0.2 9.4 5 4 3 8 8 8 7 FNIP Repeat SWIM PF04434.12 EGC28457.1 - 5.3e-05 22.6 0.3 9.4e-05 21.7 0.2 1.5 1 0 0 1 1 1 1 SWIM zinc finger PuR_N PF09182.5 EGC28457.1 - 0.062 12.9 0.0 0.12 11.9 0.0 1.6 1 0 0 1 1 1 0 Bacterial purine repressor, N-terminal FNIP PF05725.7 EGC28458.1 - 1.6e-57 191.2 53.3 2.3e-11 43.4 0.2 9.5 9 1 0 10 10 10 7 FNIP Repeat DUF1769 PF08588.5 EGC28458.1 - 0.023 14.6 1.2 31 4.6 0.1 4.4 4 1 1 5 5 5 0 Protein of unknown function (DUF1769) LRR_7 PF13504.1 EGC28458.1 - 0.2 12.0 4.9 35 5.2 0.2 5.9 6 0 0 6 6 6 0 Leucine rich repeat FNIP PF05725.7 EGC28460.1 - 2.6e-10 40.0 2.4 0.00039 20.3 0.2 3.4 1 1 0 3 3 3 3 FNIP Repeat Pex2_Pex12 PF04757.9 EGC28461.1 - 9.7e-31 106.9 9.9 1.4e-29 103.1 6.9 2.1 1 1 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-RING_2 PF13639.1 EGC28461.1 - 1.7e-08 34.1 15.5 2.9e-08 33.4 10.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC28461.1 - 2.3e-07 30.7 15.5 4.3e-07 29.8 10.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC28461.1 - 6e-07 29.0 14.9 9.7e-07 28.3 10.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28461.1 - 6.1e-06 25.7 16.7 1.1e-05 24.9 11.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC28461.1 - 8.9e-06 25.7 9.2 1.7e-05 24.8 6.4 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC28461.1 - 0.00041 20.0 17.0 0.00075 19.1 11.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF1632 PF07857.7 EGC28461.1 - 0.011 15.0 0.2 0.057 12.6 0.0 1.9 2 0 0 2 2 2 0 CEO family (DUF1632) zf-C3HC4_4 PF15227.1 EGC28461.1 - 0.039 13.8 14.3 0.13 12.1 9.9 1.9 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Cas_Cmr3 PF09700.5 EGC28461.1 - 0.045 13.1 0.0 2.1 7.6 0.0 2.1 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) TerY-C PF15616.1 EGC28461.1 - 0.11 12.3 8.9 0.2 11.5 6.1 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain zf-RING_UBOX PF13445.1 EGC28461.1 - 0.12 12.0 11.9 0.55 10.0 8.1 2.3 1 1 1 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC28461.1 - 0.36 10.7 9.8 0.69 9.7 6.8 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGC28461.1 - 0.91 9.3 10.2 1.6 8.5 7.1 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF3877 PF12993.2 EGC28462.1 - 0.0065 16.0 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function, E. rectale Gene description (DUF3877) Zn_ribbon_2 PF12674.2 EGC28462.1 - 0.023 15.0 0.1 0.044 14.1 0.0 1.5 1 0 0 1 1 1 0 Putative zinc ribbon domain Aa_trans PF01490.13 EGC28464.1 - 7.1e-19 67.5 44.2 2.5e-10 39.4 26.5 2.5 2 1 0 2 2 2 2 Transmembrane amino acid transporter protein TPR_12 PF13424.1 EGC28465.1 - 0.013 15.3 0.2 1.2 9.0 0.0 2.8 2 1 1 3 3 3 0 Tetratricopeptide repeat DUF1546 PF07571.8 EGC28467.1 - 7.3e-34 115.7 0.0 1.9e-33 114.3 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF1546) TAF PF02969.12 EGC28467.1 - 7.3e-28 96.3 0.1 1.3e-27 95.4 0.0 1.5 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Histone PF00125.19 EGC28467.1 - 0.0033 17.4 0.0 0.0076 16.3 0.0 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC28467.1 - 0.04 13.9 0.3 0.17 12.0 0.1 2.2 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC28467.1 - 0.067 12.9 0.0 0.86 9.3 0.0 2.5 2 0 0 2 2 2 0 Bromodomain associated Myb_DNA-bind_4 PF13837.1 EGC28467.1 - 0.083 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Myb/SANT-like DNA-binding domain HEAT PF02985.17 EGC28467.1 - 0.14 12.3 0.0 19 5.6 0.0 3.1 2 0 0 2 2 2 0 HEAT repeat RNB PF00773.14 EGC28468.1 - 3.2e-70 236.9 2.3 3.2e-70 236.9 1.6 1.9 2 0 0 2 2 2 1 RNB domain CorA PF01544.13 EGC28469.1 - 9.1e-44 149.6 7.3 9.1e-44 149.6 5.1 2.4 3 0 0 3 3 3 1 CorA-like Mg2+ transporter protein RRM_1 PF00076.17 EGC28470.1 - 2.3e-19 68.8 0.1 1.9e-10 40.2 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC28470.1 - 1.2e-11 44.4 0.0 1e-05 25.4 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC28470.1 - 2.5e-11 43.2 0.1 8.7e-07 28.7 0.1 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) 2C_adapt PF08793.5 EGC28470.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.0 2 0 0 2 2 2 0 2-cysteine adaptor domain RRM_3 PF08777.6 EGC28470.1 - 0.068 13.0 0.0 0.16 11.8 0.0 1.6 1 0 0 1 1 1 0 RNA binding motif BAF1_ABF1 PF04684.8 EGC28470.1 - 4.4 6.0 11.3 5.7 5.6 7.9 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Coiled PF05710.7 EGC28471.1 - 3.3e-15 56.3 15.8 3.7e-15 56.1 11.0 1.0 1 0 0 1 1 1 1 Coiled coil HEAT PF02985.17 EGC28472.1 - 3.9e-25 85.6 4.5 3e-05 23.7 0.0 10.9 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 EGC28472.1 - 7.8e-18 64.5 0.0 1.8e-05 24.9 0.0 7.3 3 2 4 7 7 7 5 HEAT repeats HEAT_EZ PF13513.1 EGC28472.1 - 2.9e-11 43.4 5.8 5.2e-05 23.5 0.0 8.6 11 0 0 11 11 11 1 HEAT-like repeat IBN_N PF03810.14 EGC28472.1 - 5.7e-11 42.1 5.4 1.7e-10 40.6 0.6 3.8 3 1 0 3 3 3 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EGC28472.1 - 8.7e-10 38.8 6.4 0.034 14.5 0.2 7.8 4 4 4 8 8 8 2 Vacuolar 14 Fab1-binding region Arm PF00514.18 EGC28472.1 - 2.2e-08 33.6 4.2 0.0095 15.7 0.0 5.1 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGC28472.1 - 5.2e-08 32.5 4.5 0.013 14.9 0.2 5.6 4 1 1 5 5 5 2 CLASP N terminal RepA_C PF04796.7 EGC28472.1 - 0.015 14.8 0.0 0.44 10.1 0.0 2.4 2 0 0 2 2 2 0 Plasmid encoded RepA protein M11L PF11099.3 EGC28472.1 - 0.45 10.2 12.8 0.077 12.7 0.2 4.0 4 1 1 5 5 5 0 Apoptosis regulator M11L like UAA PF08449.6 EGC28474.1 - 1.7e-37 129.0 29.1 2.8e-37 128.2 20.2 1.3 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGC28474.1 - 2.6e-05 23.9 13.8 2.6e-05 23.9 9.5 3.2 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGC28474.1 - 0.00019 21.4 15.8 0.00019 21.4 10.9 3.6 3 1 1 4 4 4 2 EamA-like transporter family DUF1045 PF06299.7 EGC28475.1 - 0.0011 18.7 0.0 0.0014 18.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1045) 2_5_RNA_ligase2 PF13563.1 EGC28475.1 - 0.0049 16.5 0.0 0.041 13.6 0.0 2.0 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EGC28475.1 - 0.0075 16.2 0.0 4.5 7.3 0.0 2.3 2 0 0 2 2 2 2 LigT like Phosphoesterase Dickkopf_N PF04706.7 EGC28476.1 - 0.00017 21.6 6.0 0.00017 21.6 4.2 6.3 5 2 0 5 5 5 1 Dickkopf N-terminal cysteine-rich region RGCC PF15151.1 EGC28476.1 - 0.4 11.1 2.8 0.72 10.2 1.9 1.4 1 0 0 1 1 1 0 Response gene to complement 32 protein family ENTH PF01417.15 EGC28477.1 - 0.0041 16.9 0.5 0.0073 16.1 0.3 1.4 1 0 0 1 1 1 1 ENTH domain DUF2405 PF10293.4 EGC28477.1 - 1.8 8.2 5.0 0.18 11.5 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF2405) RhoGEF PF00621.15 EGC28479.1 - 7.9e-39 133.3 4.7 7.9e-39 133.3 3.2 1.8 2 0 0 2 2 2 1 RhoGEF domain Minor_capsid_1 PF10665.4 EGC28479.1 - 0.057 13.2 4.1 2 8.2 0.0 3.7 3 0 0 3 3 3 0 Minor capsid protein ECR1_N PF14382.1 EGC28480.1 - 0.0053 16.0 0.1 0.0089 15.2 0.1 1.4 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region zf-DHHC PF01529.15 EGC28481.1 - 2e-27 95.7 10.4 2e-27 95.7 7.2 3.4 1 1 2 3 3 3 1 DHHC palmitoyltransferase FYDLN_acid PF09538.5 EGC28481.1 - 2.5 8.7 15.1 7.9 7.1 10.5 1.8 1 1 0 1 1 1 0 Protein of unknown function (FYDLN_acid) Zip PF02535.17 EGC28481.1 - 3 6.7 4.9 7.6 5.4 3.4 1.6 1 1 0 1 1 1 0 ZIP Zinc transporter Hid1 PF12722.2 EGC28481.1 - 6 4.4 23.7 7.6 4.0 16.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Rad60-SLD PF11976.3 EGC28482.1 - 2.1e-10 40.1 0.5 7e-10 38.4 0.0 2.2 2 0 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGC28482.1 - 0.0005 19.4 0.1 0.004 16.5 0.0 2.3 2 0 0 2 2 2 1 Ubiquitin family Menin PF05053.8 EGC28482.1 - 5.4 5.0 13.3 9.5 4.2 9.2 1.3 1 0 0 1 1 1 0 Menin DUF4407 PF14362.1 EGC28482.1 - 8 5.3 13.4 16 4.3 9.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SPRY PF00622.23 EGC28483.1 - 6.1e-41 139.3 7.7 9e-19 67.7 0.4 3.4 3 0 0 3 3 3 3 SPRY domain PIP5K PF01504.13 EGC28484.1 - 1.8e-60 204.1 8.4 3.9e-60 203.0 5.8 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Coiled PF05710.7 EGC28485.1 - 6.2 7.3 16.3 9.4 6.7 11.3 1.3 1 1 0 1 1 1 0 Coiled coil Ashwin PF15323.1 EGC28487.1 - 0.2 11.6 17.3 0.3 11.0 12.0 1.3 1 0 0 1 1 1 0 Developmental protein COG7 PF10191.4 EGC28487.1 - 0.6 7.9 3.2 0.73 7.6 2.2 1.1 1 0 0 1 1 1 0 Golgi complex component 7 (COG7) Ebola_NP PF05505.7 EGC28487.1 - 3.8 5.4 22.0 4.3 5.2 15.3 1.1 1 0 0 1 1 1 0 Ebola nucleoprotein PCI_Csn8 PF10075.4 EGC28488.1 - 1.8e-29 102.3 0.1 2.7e-29 101.7 0.0 1.2 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGC28488.1 - 0.00043 19.9 0.2 0.00053 19.6 0.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EGC28488.1 - 0.043 14.1 0.3 0.12 12.7 0.2 1.9 1 1 0 1 1 1 0 PCI domain TBP PF00352.16 EGC28489.1 - 3.6e-67 221.7 1.5 1.3e-33 114.1 0.1 2.1 2 0 0 2 2 2 2 Transcription factor TFIID (or TATA-binding protein, TBP) DUF3378 PF11858.3 EGC28489.1 - 0.00013 21.9 0.0 0.18 11.8 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF3378) DUF4295 PF14128.1 EGC28489.1 - 0.091 12.3 0.2 0.22 11.1 0.0 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4295) Ribosomal_S24e PF01282.14 EGC28490.1 - 2e-32 110.7 0.6 3.4e-32 110.0 0.1 1.6 1 1 1 2 2 2 1 Ribosomal protein S24e Cmc1 PF08583.5 EGC28491.1 - 1.1e-19 70.0 5.9 1.4e-19 69.6 3.9 1.4 1 1 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like Ins_P5_2-kin PF06090.7 EGC28491.1 - 0.0035 16.4 0.2 0.0035 16.4 0.2 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase NDUF_B7 PF05676.8 EGC28491.1 - 0.038 13.4 0.4 0.061 12.7 0.3 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Polyoma_coat PF00718.15 EGC28491.1 - 0.12 11.2 0.0 0.14 11.0 0.0 1.1 1 0 0 1 1 1 0 Polyomavirus coat protein CHCH PF06747.8 EGC28491.1 - 1.2 9.1 4.3 27 4.8 2.9 2.3 1 1 1 2 2 2 0 CHCH domain 5_nucleotid PF05761.9 EGC28492.1 - 3.6e-135 450.9 2.8 4.6e-135 450.6 1.9 1.1 1 0 0 1 1 1 1 5' nucleotidase family Hydrolase_6 PF13344.1 EGC28492.1 - 0.11 12.3 0.0 0.27 11.1 0.0 1.6 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase F5_F8_type_C PF00754.20 EGC28494.1 - 6.4e-27 93.9 1.3 6.4e-27 93.9 0.9 1.9 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC28494.1 - 1.1e-19 69.8 1.0 2.4e-19 68.7 0.2 2.0 2 0 0 2 2 2 1 H-type lectin domain DUF3012 PF11216.3 EGC28494.1 - 0.096 12.3 0.5 2.1 8.1 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3012) Arrestin_C PF02752.17 EGC28495.1 - 1.1e-11 44.9 7.0 9.1e-11 42.0 3.1 6.2 3 2 0 3 3 3 2 Arrestin (or S-antigen), C-terminal domain Arrestin_N PF00339.24 EGC28495.1 - 6.6e-07 29.2 8.5 1.2e-06 28.4 0.0 4.0 3 1 1 4 4 4 1 Arrestin (or S-antigen), N-terminal domain RCC1 PF00415.13 EGC28496.1 - 4e-33 113.3 0.0 2.5e-10 40.3 0.0 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC28496.1 - 9.5e-24 82.4 14.2 8.5e-10 37.9 0.0 6.6 7 0 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat TPR_7 PF13176.1 EGC28497.1 - 0.13 12.1 0.1 0.3 10.9 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase PF00069.20 EGC28498.1 - 1.4e-65 221.0 0.0 1.4e-65 221.0 0.0 2.8 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28498.1 - 2.2e-30 105.5 1.4 3.5e-30 104.9 0.0 2.1 3 0 0 3 3 3 1 Protein tyrosine kinase Sina PF03145.11 EGC28499.1 - 1.7e-10 40.9 0.7 2.9e-10 40.1 0.5 1.4 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EGC28499.1 - 0.003 17.1 7.9 0.007 16.0 5.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CDC45 PF02724.9 EGC28499.1 - 0.0089 14.1 17.1 0.012 13.6 11.8 1.1 1 0 0 1 1 1 1 CDC45-like protein Nop14 PF04147.7 EGC28499.1 - 0.012 13.5 24.8 0.017 13.0 17.2 1.2 1 0 0 1 1 1 0 Nop14-like family Astro_capsid PF03115.9 EGC28499.1 - 0.25 9.5 2.9 0.29 9.3 2.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor VID27 PF08553.5 EGC28499.1 - 0.84 7.7 15.8 1.3 7.1 11.0 1.2 1 0 0 1 1 1 0 VID27 cytoplasmic protein zf-C3HC4_2 PF13923.1 EGC28499.1 - 1.3 9.1 12.6 3.3 7.8 8.7 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGC28499.1 - 1.5 8.7 7.8 3.6 7.5 5.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) DUF3295 PF11702.3 EGC28499.1 - 1.8 7.4 15.2 2.9 6.7 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) zf-TRAF PF02176.13 EGC28499.1 - 2 8.8 9.9 1.6 9.1 2.2 3.0 1 1 2 3 3 3 0 TRAF-type zinc finger Daxx PF03344.10 EGC28499.1 - 2 6.7 25.3 0.68 8.3 15.7 1.4 2 0 0 2 2 2 0 Daxx Family zf-RING_5 PF14634.1 EGC28499.1 - 2.2 8.0 12.0 11 5.8 8.3 2.2 1 1 0 1 1 1 0 zinc-RING finger domain Paf1 PF03985.8 EGC28499.1 - 2.6 6.7 18.2 4.1 6.0 12.6 1.2 1 0 0 1 1 1 0 Paf1 DUF1510 PF07423.6 EGC28499.1 - 2.7 7.3 18.7 0.3 10.4 10.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Sporozoite_P67 PF05642.6 EGC28499.1 - 3.5 5.3 14.2 5.5 4.7 9.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Sigma70_ner PF04546.8 EGC28499.1 - 5.4 6.5 25.5 12 5.4 17.7 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region HSP90 PF00183.13 EGC28499.1 - 6 5.1 22.5 2.9 6.2 13.2 1.9 2 0 0 2 2 2 0 Hsp90 protein CENP-T PF15511.1 EGC28499.1 - 7 5.7 16.0 12 5.0 11.1 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T DUF2457 PF10446.4 EGC28499.1 - 9.6 4.8 44.2 17 3.9 30.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) LSM PF01423.17 EGC28500.1 - 6.5e-13 48.0 0.5 6.5e-13 48.0 0.3 1.5 2 0 0 2 2 2 1 LSM domain SM-ATX PF14438.1 EGC28500.1 - 0.00021 21.1 0.0 0.00021 21.1 0.0 1.7 2 0 0 2 2 2 1 Ataxin 2 SM domain DUF1256 PF06866.6 EGC28500.1 - 0.043 13.0 0.1 0.057 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) LSM14 PF12701.2 EGC28500.1 - 0.069 12.9 0.5 0.11 12.2 0.3 1.4 1 1 0 1 1 1 0 Scd6-like Sm domain DEAD PF00270.24 EGC28501.1 - 7.4e-31 106.9 1.0 1.8e-30 105.6 0.3 1.8 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC28501.1 - 5.8e-22 77.3 0.0 1.4e-21 76.0 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1811 PF08838.5 EGC28501.1 - 0.012 15.5 0.0 0.03 14.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1811) DUF3439 PF11921.3 EGC28502.1 - 0.78 9.4 10.3 2.2 8.0 7.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) PspB PF06667.7 EGC28503.1 - 0.33 10.9 5.0 20 5.1 0.1 3.4 3 0 0 3 3 3 0 Phage shock protein B OTU PF02338.14 EGC28504.1 - 3.4e-05 24.4 0.0 3.4e-05 24.4 0.0 3.0 2 1 0 2 2 2 1 OTU-like cysteine protease LMBR1 PF04791.11 EGC28504.1 - 0.37 9.3 2.4 0.39 9.2 1.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Neur_chan_memb PF02932.11 EGC28504.1 - 0.37 10.6 5.7 0.51 10.1 4.0 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Band_3_cyto PF07565.8 EGC28504.1 - 0.42 10.0 16.2 0.65 9.4 11.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.5 EGC28504.1 - 0.77 7.8 63.9 0.95 7.5 44.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EGC28504.1 - 1.2 7.3 47.3 1.4 7.0 32.8 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nucleoplasmin PF03066.10 EGC28505.1 - 0.0003 20.3 5.8 0.0003 20.3 4.0 2.1 2 0 0 2 2 2 1 Nucleoplasmin PBP1_TM PF14812.1 EGC28505.1 - 0.03 14.6 10.6 0.03 14.6 7.4 2.3 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pap_E4 PF02711.9 EGC28505.1 - 1 10.1 4.4 22 5.9 0.6 2.1 2 0 0 2 2 2 0 E4 protein Nop14 PF04147.7 EGC28505.1 - 1.5 6.6 15.4 2 6.2 10.7 1.2 1 0 0 1 1 1 0 Nop14-like family Sigma70_ner PF04546.8 EGC28505.1 - 2.4 7.7 13.7 0.29 10.7 5.0 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region SDA1 PF05285.7 EGC28505.1 - 5.3 6.2 16.7 3.8 6.7 0.2 2.0 2 0 0 2 2 2 0 SDA1 Pkinase PF00069.20 EGC28506.1 - 1.2e-61 208.1 0.0 3e-61 206.8 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28506.1 - 3.2e-46 157.5 0.0 6.5e-46 156.4 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28506.1 - 5.9e-05 22.1 0.0 0.00012 21.1 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC28506.1 - 0.0049 16.6 0.0 0.0094 15.7 0.0 1.4 1 0 0 1 1 1 1 Phosphotransferase enzyme family CBFD_NFYB_HMF PF00808.18 EGC28508.1 - 3.2e-20 71.9 0.4 4.2e-20 71.5 0.3 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC28508.1 - 5.5e-11 42.4 0.0 6.5e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Peptidase_M26_N PF05342.9 EGC28508.1 - 0.011 14.7 0.1 0.013 14.5 0.0 1.1 1 0 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region RPAP3_C PF13877.1 EGC28508.1 - 0.041 13.8 0.1 0.083 12.8 0.1 1.6 1 0 0 1 1 1 0 Potential Monad-binding region of RPAP3 zf-HIT PF04438.11 EGC28509.1 - 8.4e-06 25.3 7.4 1.4e-05 24.6 5.1 1.3 1 0 0 1 1 1 1 HIT zinc finger Peptidase_C54 PF03416.14 EGC28510.1 - 2.3e-25 89.2 0.1 2.3e-25 89.2 0.1 2.8 2 1 1 3 3 3 1 Peptidase family C54 Med15 PF09606.5 EGC28510.1 - 0.00019 19.8 48.5 0.00019 19.8 33.6 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4557 PF15101.1 EGC28510.1 - 4.4 7.0 23.7 9.2 6.0 16.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Methyltrans_SAM PF10672.4 EGC28511.1 - 9.7e-26 90.2 0.0 1.5e-25 89.6 0.0 1.2 1 0 0 1 1 1 1 S-adenosylmethionine-dependent methyltransferase Methyltransf_26 PF13659.1 EGC28511.1 - 1.6e-05 24.9 0.0 2.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGC28511.1 - 6.1e-05 22.4 0.0 0.00012 21.5 0.0 1.5 1 1 0 1 1 1 1 Conserved hypothetical protein 95 Methyltransf_25 PF13649.1 EGC28511.1 - 0.11 12.8 0.0 0.24 11.8 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Pirin PF02678.11 EGC28512.1 - 2.4e-28 98.1 0.0 4.2e-28 97.3 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGC28512.1 - 5.3e-12 45.7 0.0 8e-07 29.0 0.0 2.7 2 1 1 3 3 3 2 Pirin C-terminal cupin domain Cupin_2 PF07883.6 EGC28512.1 - 0.01 15.3 0.0 0.048 13.1 0.0 1.9 2 0 0 2 2 2 0 Cupin domain zf-CCCH PF00642.19 EGC28513.1 - 0.013 15.1 3.0 0.022 14.4 2.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGC28513.1 - 0.15 12.0 3.9 0.31 11.0 2.7 1.5 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type MIF4G PF02854.14 EGC28514.1 - 6.8e-20 71.3 16.5 1.9e-19 69.9 7.8 2.9 2 1 0 2 2 2 2 MIF4G domain MA3 PF02847.12 EGC28514.1 - 3.3e-16 58.9 2.2 3.3e-16 58.9 1.5 2.9 3 0 0 3 3 3 1 MA3 domain Hydantoinase_A PF01968.13 EGC28514.1 - 9.7 5.1 5.7 1.3 8.0 0.2 2.2 2 1 0 2 2 2 0 Hydantoinase/oxoprolinase Pyr_redox_3 PF13738.1 EGC28515.1 - 5.8e-37 127.7 0.0 3.5e-36 125.1 0.0 1.9 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC28515.1 - 3.6e-07 30.2 0.0 9.5e-07 28.8 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC28515.1 - 6e-06 25.3 0.0 0.00023 20.2 0.0 2.4 3 0 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGC28515.1 - 0.00019 21.2 0.1 0.0033 17.2 0.0 2.2 1 1 0 1 1 1 1 FAD-NAD(P)-binding Fer4_18 PF13746.1 EGC28516.1 - 0.0032 17.8 0.6 0.0034 17.7 0.4 1.2 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGC28516.1 - 0.05 13.5 0.3 0.076 12.9 0.2 1.3 1 0 0 1 1 1 0 4Fe-4S binding domain Fer4_16 PF13484.1 EGC28516.1 - 0.28 11.9 3.6 0.19 12.4 1.3 1.6 1 1 1 2 2 2 0 4Fe-4S double cluster binding domain Claudin_2 PF13903.1 EGC28517.1 - 1.7e-05 24.6 6.6 1.7e-05 24.6 4.6 2.7 2 1 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction MARVEL PF01284.18 EGC28517.1 - 0.005 16.6 10.1 0.005 16.6 7.0 2.3 2 1 0 2 2 2 1 Membrane-associating domain Amastin PF07344.6 EGC28517.1 - 0.0053 16.3 2.7 0.0096 15.5 1.8 1.6 1 1 0 1 1 1 1 Amastin surface glycoprotein Na_Ca_ex PF01699.19 EGC28517.1 - 0.025 14.2 7.1 0.27 10.8 4.9 2.2 1 1 0 1 1 1 0 Sodium/calcium exchanger protein DUF4131 PF13567.1 EGC28517.1 - 0.037 13.4 6.8 0.061 12.7 0.7 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) TMEM190 PF15431.1 EGC28517.1 - 0.095 12.6 0.0 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Transmembrane protein 190 ABC2_membrane_4 PF12730.2 EGC28517.1 - 0.11 11.7 19.1 0.66 9.0 12.9 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein Claudin_3 PF06653.6 EGC28517.1 - 0.45 10.2 14.4 0.64 9.7 0.6 2.9 2 1 1 3 3 3 0 Tight junction protein, Claudin-like ABC2_membrane_5 PF13346.1 EGC28517.1 - 0.96 8.7 14.6 0.034 13.4 4.8 2.2 3 0 0 3 3 3 0 ABC-2 family transporter protein Wzy_C PF04932.10 EGC28517.1 - 2.1 8.0 8.9 2 8.2 4.4 2.0 1 1 1 2 2 2 0 O-Antigen ligase DUF3671 PF12420.3 EGC28517.1 - 2.7 8.0 8.5 1.9 8.4 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function MS_channel PF00924.13 EGC28517.1 - 4.5 6.5 7.7 7.4 5.8 5.4 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel DUF4577 PF15145.1 EGC28517.1 - 5.3 6.9 6.4 0.87 9.5 0.2 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4577) DUF4013 PF13197.1 EGC28517.1 - 8 5.7 18.4 0.038 13.3 4.7 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) TFIIIC_delta PF12657.2 EGC28518.1 - 0.053 13.2 0.0 0.064 12.9 0.0 1.2 1 0 0 1 1 1 0 Transcription factor IIIC subunit delta N-term zf-C3HC4_3 PF13920.1 EGC28519.1 - 1e-06 28.3 6.2 2.4e-06 27.1 4.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28519.1 - 1.7e-05 24.3 11.6 0.00017 21.1 8.0 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28519.1 - 6.3e-05 22.9 12.2 0.00092 19.1 8.5 2.6 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC28519.1 - 9.3e-05 22.0 10.5 0.0003 20.4 7.3 1.9 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC28519.1 - 0.00032 20.4 8.6 0.0009 19.0 6.0 1.8 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGC28519.1 - 0.013 15.3 4.9 0.013 15.3 3.4 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC28519.1 - 0.014 15.5 5.3 0.029 14.4 3.7 1.6 1 0 0 1 1 1 0 RING-H2 zinc finger zf-RING_4 PF14570.1 EGC28519.1 - 0.085 12.4 8.2 0.17 11.5 5.7 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EGC28519.1 - 0.086 12.8 1.5 0.23 11.4 1.0 1.8 1 0 0 1 1 1 0 zinc-finger Prok-RING_4 PF14447.1 EGC28519.1 - 0.87 9.1 5.4 2 8.0 3.8 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Sterile PF03015.14 EGC28519.1 - 2.6 8.3 7.0 4.7 7.5 0.8 2.5 1 1 1 2 2 2 0 Male sterility protein Helicase_Sgs1 PF11408.3 EGC28520.1 - 0.047 13.5 0.4 0.069 12.9 0.3 1.3 1 0 0 1 1 1 0 Sgs1 RecQ helicase Big_2 PF02368.13 EGC28521.1 - 1.7 8.6 5.0 17 5.3 0.4 3.5 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 2) RasGAP PF00616.14 EGC28522.1 - 3e-51 173.8 0.1 8.9e-51 172.3 0.1 1.9 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EGC28522.1 - 3.5e-19 68.4 0.2 1.4e-18 66.4 0.0 2.1 2 0 0 2 2 2 1 C2 domain NodA PF02474.10 EGC28522.1 - 0.15 11.2 0.0 0.28 10.4 0.0 1.3 1 0 0 1 1 1 0 Nodulation protein A (NodA) RtcB PF01139.12 EGC28523.1 - 7.9e-146 486.3 0.0 9.6e-146 486.0 0.0 1.0 1 0 0 1 1 1 1 tRNA-splicing ligase RtcB FlxA PF14282.1 EGC28524.1 - 0.41 10.6 3.2 0.68 9.9 2.2 1.4 1 1 0 1 1 1 0 FlxA-like protein XhlA PF10779.4 EGC28524.1 - 0.77 9.7 4.5 1.7 8.6 3.1 1.6 1 1 0 1 1 1 0 Haemolysin XhlA Peptidase_M41 PF01434.13 EGC28526.1 - 0.0081 15.6 5.6 0.011 15.1 3.9 1.2 1 0 0 1 1 1 1 Peptidase family M41 Herpes_UL6 PF01763.11 EGC28526.1 - 0.28 9.3 4.8 0.36 8.9 3.3 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like s48_45 PF07422.8 EGC28526.1 - 1.9 8.5 10.3 0.24 11.4 2.8 2.5 2 1 0 2 2 2 0 Sexual stage antigen s48/45 domain DUF2193 PF09959.4 EGC28527.1 - 0.18 10.0 3.6 3.7 5.6 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2193) bPH_3 PF14470.1 EGC28527.1 - 0.2 11.9 13.2 0.083 13.1 2.0 2.5 1 1 1 2 2 2 0 Bacterial PH domain GSHPx PF00255.14 EGC28527.1 - 0.36 10.2 4.2 0.19 11.1 0.8 1.9 2 0 0 2 2 2 0 Glutathione peroxidase FlaC_arch PF05377.6 EGC28527.1 - 5 7.0 14.3 1 9.2 0.3 3.6 1 1 2 3 3 3 0 Flagella accessory protein C (FlaC) UQ_con PF00179.21 EGC28528.1 - 2.6e-36 124.1 0.1 3.5e-36 123.7 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sigma70_ner PF04546.8 EGC28528.1 - 0.024 14.2 9.5 0.034 13.7 6.6 1.1 1 0 0 1 1 1 0 Sigma-70, non-essential region RWD PF05773.17 EGC28528.1 - 0.077 12.9 0.4 0.14 12.0 0.3 1.7 1 1 0 1 1 1 0 RWD domain Cwf_Cwc_15 PF04889.7 EGC28528.1 - 0.31 10.6 13.3 0.39 10.4 9.2 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein UPF0560 PF10577.4 EGC28528.1 - 0.55 8.4 4.8 0.68 8.1 3.3 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4611 PF15387.1 EGC28528.1 - 0.55 10.4 7.9 0.88 9.7 5.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) DUF2457 PF10446.4 EGC28528.1 - 0.98 8.0 15.0 1.1 7.8 10.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGC28528.1 - 3.8 5.4 12.3 4.9 5.0 8.5 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2076 PF09849.4 EGC28528.1 - 4.7 7.2 10.5 5.8 6.8 7.3 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) Fis1_TPR_C PF14853.1 EGC28529.1 - 4.4e-08 32.8 0.6 1.1e-07 31.6 0.4 1.7 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_11 PF13414.1 EGC28529.1 - 0.00038 20.0 0.2 0.00072 19.1 0.2 1.4 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EGC28529.1 - 0.0017 18.1 0.6 0.027 14.3 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC28529.1 - 0.005 17.4 0.0 0.35 11.6 0.0 1.8 1 1 1 2 2 2 2 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGC28529.1 - 0.011 15.0 0.1 0.018 14.2 0.0 1.4 1 0 0 1 1 1 0 Fis1 N-terminal tetratricopeptide repeat TPR_8 PF13181.1 EGC28529.1 - 0.012 15.3 0.5 0.012 15.3 0.3 3.0 2 2 2 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC28529.1 - 0.013 15.3 0.2 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC28529.1 - 0.016 15.3 4.2 0.019 15.0 1.8 2.1 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGC28529.1 - 0.02 15.2 0.8 0.036 14.4 0.5 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC28529.1 - 0.058 13.0 0.1 0.17 11.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat Zip PF02535.17 EGC28529.1 - 5.8 5.8 6.4 8.7 5.2 4.4 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Aa_trans PF01490.13 EGC28531.1 - 5.8e-11 41.5 33.2 1.4e-10 40.2 23.0 1.6 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EGC28531.1 - 0.00028 19.8 19.4 0.00028 19.8 13.5 2.8 2 1 1 3 3 3 1 Tryptophan/tyrosine permease family DUF2839 PF10999.3 EGC28531.1 - 0.14 12.1 3.5 3 7.9 0.1 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2839) DUF3072 PF11272.3 EGC28531.1 - 0.17 11.5 0.0 0.33 10.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3072) CorA PF01544.13 EGC28532.1 - 4.9 6.1 20.6 0.48 9.4 5.7 2.2 2 0 0 2 2 2 0 CorA-like Mg2+ transporter protein Pkinase PF00069.20 EGC28533.1 - 3.2e-64 216.5 0.0 7.2e-64 215.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28533.1 - 2.5e-46 157.8 0.0 4.1e-46 157.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28533.1 - 6.7e-08 31.8 0.0 1.7e-05 23.9 0.0 2.4 2 0 0 2 2 2 2 Kinase-like Apis_Csd PF11671.3 EGC28533.1 - 0.21 11.3 25.1 1.7 8.4 6.2 2.6 2 0 0 2 2 2 0 Complementary sex determiner protein DUF1383 PF07134.6 EGC28534.1 - 0.061 12.2 1.3 0.069 12.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1383) YkyB PF14177.1 EGC28534.1 - 0.086 12.9 0.8 0.098 12.7 0.5 1.1 1 0 0 1 1 1 0 YkyB-like protein dNK PF01712.14 EGC28534.1 - 0.15 11.9 2.1 0.56 10.1 1.3 2.0 1 1 1 2 2 2 0 Deoxynucleoside kinase DUF3452 PF11934.3 EGC28534.1 - 0.41 9.9 3.7 0.64 9.3 2.1 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) LRR_6 PF13516.1 EGC28536.1 - 1.3e-05 24.7 9.4 0.89 9.8 0.0 5.7 6 0 0 6 6 6 3 Leucine Rich repeat LRR_7 PF13504.1 EGC28536.1 - 2.2e-05 23.9 7.7 11 6.6 0.2 6.1 5 0 0 5 5 5 2 Leucine rich repeat LRR_4 PF12799.2 EGC28536.1 - 0.00012 21.6 10.7 0.064 12.8 0.1 5.1 2 2 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC28536.1 - 0.0003 20.3 15.7 4.2 7.7 0.5 5.9 5 2 0 5 5 5 3 Leucine Rich Repeat LRR_8 PF13855.1 EGC28536.1 - 7.4 6.4 14.6 6.1 6.6 0.0 4.6 4 2 0 4 4 4 0 Leucine rich repeat EGF_2 PF07974.8 EGC28537.1 - 1.9e-05 24.6 30.3 0.00083 19.4 7.5 3.1 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC28537.1 - 0.028 14.4 1.7 0.028 14.4 1.2 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC28537.1 - 0.22 11.4 23.7 1.9 8.4 4.8 2.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC28538.1 - 0.048 13.7 4.7 0.038 14.0 1.2 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF SNF2_N PF00176.18 EGC28539.1 - 6.1e-76 255.0 0.7 6.1e-76 255.0 0.5 2.7 3 0 0 3 3 3 1 SNF2 family N-terminal domain HSA PF07529.8 EGC28539.1 - 4.9e-18 64.6 2.8 4.9e-18 64.6 2.0 3.4 2 1 0 2 2 2 1 HSA Helicase_C PF00271.26 EGC28539.1 - 3.7e-15 55.5 0.3 2.4e-14 52.9 0.0 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-bind_6 PF13921.1 EGC28539.1 - 3.7e-05 23.7 0.8 0.00027 20.9 0.5 2.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGC28539.1 - 0.033 14.2 0.1 0.14 12.2 0.1 2.2 1 1 0 1 1 1 0 Myb-like DNA-binding domain Tnp_DNA_bind PF14706.1 EGC28539.1 - 5.7 6.7 7.6 1.5 8.5 0.9 3.2 1 1 2 3 3 3 0 Transposase DNA-binding Adaptin_N PF01602.15 EGC28540.1 - 6.9e-127 423.9 18.6 1.2e-126 423.1 12.9 1.4 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGC28540.1 - 2.5e-12 46.8 1.5 2.4e-06 27.7 0.1 3.7 2 1 0 3 3 3 3 HEAT repeats AP3B1_C PF14796.1 EGC28540.1 - 5.1e-12 45.7 0.2 1.2e-11 44.5 0.1 1.6 1 0 0 1 1 1 1 Clathrin-adaptor complex-3 beta-1 subunit C-terminal HEAT PF02985.17 EGC28540.1 - 1.2e-08 34.2 2.1 0.065 13.3 0.0 6.7 6 1 1 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EGC28540.1 - 0.00046 20.6 0.1 1.9 9.1 0.0 4.7 4 0 0 4 4 4 1 HEAT-like repeat MOR2-PAG1_C PF14225.1 EGC28540.1 - 0.00054 19.7 0.2 0.0019 17.9 0.1 2.0 1 1 0 1 1 1 1 Cell morphogenesis C-terminal B2-adapt-app_C PF09066.5 EGC28540.1 - 0.0052 16.6 0.2 0.032 14.0 0.1 2.4 2 0 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain CBF PF03914.12 EGC28542.1 - 3.8e-45 153.2 1.1 2.1e-44 150.8 0.1 2.6 3 0 0 3 3 3 1 CBF/Mak21 family SNARE_assoc PF09335.6 EGC28543.1 - 0.0055 16.9 5.3 0.0055 16.9 3.6 1.7 2 0 0 2 2 2 1 SNARE associated Golgi protein ATG16 PF08614.6 EGC28544.1 - 1.8e-49 168.2 20.8 2.5e-49 167.7 14.4 1.2 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) WD40 PF00400.27 EGC28544.1 - 2.9e-44 147.3 31.0 6.8e-09 35.2 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Serglycin PF04360.7 EGC28544.1 - 2e-05 24.3 0.9 3.8e-05 23.4 0.6 1.5 1 0 0 1 1 1 1 Serglycin MCP_N PF05581.7 EGC28544.1 - 0.28 11.3 2.9 0.23 11.6 0.3 2.1 2 1 0 2 2 2 0 Vibrio chemotaxis protein N terminus Exonuc_VII_L PF02601.10 EGC28544.1 - 0.43 9.7 13.0 0.84 8.7 9.0 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit IncA PF04156.9 EGC28544.1 - 0.6 9.6 22.7 0.42 10.1 11.5 2.7 2 1 1 3 3 3 0 IncA protein Nup54 PF13874.1 EGC28544.1 - 0.96 9.1 14.8 1.4 8.6 2.9 2.6 2 1 1 3 3 3 0 Nucleoporin complex subunit 54 Reo_sigmaC PF04582.7 EGC28544.1 - 2 7.4 8.1 3.6 6.6 5.6 1.3 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V_ATPase_I PF01496.14 EGC28544.1 - 4.1 5.1 13.1 5.9 4.6 9.1 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family zf-C2H2_jaz PF12171.3 EGC28545.1 - 4.2e-08 33.0 4.4 4.2e-08 33.0 3.0 1.9 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC28545.1 - 0.0016 18.6 2.4 0.0031 17.6 1.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGC28545.1 - 0.0093 16.2 3.1 0.019 15.2 2.1 1.5 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_2 PF12756.2 EGC28545.1 - 0.016 15.3 1.9 0.016 15.3 1.3 2.0 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EGC28545.1 - 0.04 13.7 0.5 0.04 13.7 0.3 1.8 2 0 0 2 2 2 0 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_4 PF13894.1 EGC28545.1 - 0.044 14.1 0.9 0.093 13.1 0.6 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger Pkinase PF00069.20 EGC28547.1 - 1.9e-46 158.3 2.5 2.7e-36 125.0 0.1 2.4 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28547.1 - 3.2e-30 105.0 0.5 9.2e-24 83.9 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Acetyltransf_1 PF00583.19 EGC28547.1 - 7.5e-07 29.1 0.0 1.9e-06 27.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC28547.1 - 8.7e-06 25.8 0.0 3.4e-05 23.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC28547.1 - 0.004 17.0 0.0 0.0085 15.9 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Kinase-like PF14531.1 EGC28547.1 - 0.017 14.1 0.0 0.035 13.0 0.0 1.6 1 0 0 1 1 1 0 Kinase-like Acetyltransf_10 PF13673.1 EGC28547.1 - 0.037 14.1 0.0 0.18 11.9 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_6 PF13480.1 EGC28547.1 - 0.29 11.0 0.0 0.52 10.2 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PEARLI-4 PF05278.7 EGC28548.1 - 0.0047 16.3 2.6 0.0047 16.3 1.8 1.4 1 1 0 1 1 1 1 Arabidopsis phospholipase-like protein (PEARLI 4) Rapamycin_bind PF08771.6 EGC28548.1 - 0.011 15.7 2.0 0.011 15.7 1.4 2.1 2 1 0 2 2 2 0 Rapamycin binding domain NPV_P10 PF05531.7 EGC28548.1 - 0.025 14.8 3.6 0.025 14.8 2.5 2.3 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF1319 PF07028.6 EGC28548.1 - 0.026 14.7 5.5 0.026 14.7 3.8 2.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1319) DUF1664 PF07889.7 EGC28548.1 - 0.096 12.4 5.0 0.18 11.6 3.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) ATP-synt_B PF00430.13 EGC28548.1 - 0.11 12.3 8.0 0.018 14.8 2.9 1.7 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) DNA_repr_REX1B PF14966.1 EGC28548.1 - 0.19 12.1 4.9 0.085 13.2 1.7 1.7 2 0 0 2 2 2 0 DNA repair REX1-B DUF489 PF04356.7 EGC28548.1 - 0.55 9.7 7.9 0.61 9.6 5.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF489) Muted PF14942.1 EGC28548.1 - 0.75 9.6 13.0 2.7 7.8 0.4 2.2 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein Syntaxin-6_N PF09177.6 EGC28548.1 - 1.1 9.6 9.0 0.75 10.2 2.9 2.3 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DUF2203 PF09969.4 EGC28548.1 - 1.2 9.3 5.4 1.3 9.2 1.8 2.0 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3533 PF12051.3 EGC28548.1 - 1.9 7.1 5.5 3 6.5 3.3 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3533) DUF948 PF06103.6 EGC28548.1 - 3.6 7.4 9.3 0.77 9.6 1.8 2.6 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Z1 PF10593.4 EGC28548.1 - 6.8 5.8 10.6 27 3.8 7.3 1.9 1 1 0 1 1 1 0 Z1 domain BTB PF00651.26 EGC28549.1 - 1.1e-07 31.8 1.3 2e-07 30.9 0.9 1.5 1 0 0 1 1 1 1 BTB/POZ domain SAM_2 PF07647.12 EGC28549.1 - 0.032 14.0 0.1 0.26 11.1 0.0 2.5 1 1 1 2 2 2 0 SAM domain (Sterile alpha motif) Adaptin_binding PF10199.4 EGC28549.1 - 0.092 13.0 4.6 0.23 11.7 3.2 1.7 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Spore_coat_CotO PF14153.1 EGC28550.1 - 1.8e-05 24.2 1.4 1.8e-05 24.2 1.0 2.8 2 1 0 2 2 2 1 Spore coat protein CotO Pkr1 PF08636.5 EGC28550.1 - 0.0041 17.1 1.7 0.0066 16.4 1.2 1.2 1 0 0 1 1 1 1 ER protein Pkr1 DUF4083 PF13314.1 EGC28550.1 - 0.59 10.0 0.0 0.59 10.0 0.0 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4083) Toprim_2 PF13155.1 EGC28551.1 - 0.55 10.5 0.1 0.55 10.5 0.0 2.5 2 1 0 2 2 2 0 Toprim-like UBN2 PF14223.1 EGC28553.1 - 0.016 14.9 0.4 0.025 14.3 0.2 1.3 1 1 0 1 1 1 0 gag-polypeptide of LTR copia-type SmpA_OmlA PF04355.8 EGC28553.1 - 4.5 6.9 7.2 4.6 6.9 1.2 2.4 2 0 0 2 2 2 0 SmpA / OmlA family DUF3439 PF11921.3 EGC28554.1 - 0.1 12.3 3.2 0.24 11.1 2.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SAM_2 PF07647.12 EGC28555.1 - 0.016 15.0 0.8 0.037 13.8 0.0 2.0 2 0 0 2 2 2 0 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EGC28556.1 - 5.3e-43 147.0 1.7 4.8e-37 127.5 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28556.1 - 1e-19 70.6 0.0 6.9e-18 64.6 0.0 2.3 1 1 1 2 2 2 2 Protein tyrosine kinase SAM_1 PF00536.25 EGC28556.1 - 2.8e-06 27.3 0.1 7.5e-06 26.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC28556.1 - 2e-05 24.3 0.1 5e-05 23.0 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) RIO1 PF01163.17 EGC28556.1 - 0.00024 20.5 0.0 0.00054 19.3 0.0 1.6 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC28556.1 - 0.0004 20.2 0.2 0.00061 19.6 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC28556.1 - 0.02 13.9 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC28556.1 - 0.053 12.4 0.0 0.43 9.4 0.0 2.4 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.20 EGC28557.1 - 9.3e-58 195.4 0.1 2.3e-57 194.1 0.1 1.6 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28557.1 - 7.9e-31 107.0 0.0 1.3e-30 106.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.25 EGC28557.1 - 1.3e-08 34.8 0.2 3.5e-08 33.4 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC28557.1 - 7.8e-06 25.6 0.1 1.9e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.18 EGC28557.1 - 9e-06 25.5 0.0 0.00051 19.8 0.2 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC28557.1 - 0.00019 20.8 0.1 0.00032 20.1 0.1 1.4 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGC28557.1 - 0.099 11.6 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family BRCT PF00533.21 EGC28558.1 - 6.5e-53 176.8 15.4 3.1e-14 52.8 0.1 8.6 8 0 0 8 8 8 7 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC28558.1 - 2.7e-37 126.4 0.5 3e-10 39.8 0.0 7.0 7 0 0 7 7 7 5 twin BRCT domain Nup35_RRM PF05172.8 EGC28558.1 - 0.0037 16.9 0.6 0.027 14.2 0.0 2.7 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif F-box-like PF12937.2 EGC28559.1 - 0.043 13.5 0.1 0.12 12.1 0.1 1.8 1 0 0 1 1 1 0 F-box-like AATF-Che1 PF13339.1 EGC28561.1 - 3e-24 85.6 7.5 3e-24 85.6 5.2 3.8 3 2 0 3 3 3 1 Apoptosis antagonizing transcription factor TRAUB PF08164.7 EGC28561.1 - 1.5e-22 79.4 0.7 1.5e-22 79.4 0.5 3.5 4 0 0 4 4 4 1 Apoptosis-antagonizing transcription factor, C-terminal GET2 PF08690.5 EGC28561.1 - 0.00098 18.4 8.1 0.00098 18.4 5.6 3.0 3 1 0 3 3 3 1 GET complex subunit GET2 DUF4447 PF14590.1 EGC28561.1 - 0.051 13.1 0.2 0.051 13.1 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4447) Tim17 PF02466.14 EGC28563.1 - 0.0057 16.7 3.4 0.01 15.8 2.4 1.4 1 1 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family DUF3042 PF11240.3 EGC28563.1 - 0.098 12.4 5.9 3.6 7.4 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3042) NUDIX_2 PF13869.1 EGC28564.1 - 3e-75 251.6 0.1 3.4e-75 251.5 0.1 1.0 1 0 0 1 1 1 1 Nucleotide hydrolase NUDIX PF00293.23 EGC28564.1 - 0.0011 18.5 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 NUDIX domain Mito_carr PF00153.22 EGC28565.1 - 3e-69 228.8 7.8 9.6e-24 82.9 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein PQ-loop PF04193.9 EGC28566.1 - 1.1e-09 37.7 12.4 1.9e-07 30.5 0.6 3.4 4 0 0 4 4 4 2 PQ loop repeat DUF872 PF05915.7 EGC28566.1 - 0.0063 16.3 0.7 0.025 14.4 0.0 2.3 2 0 0 2 2 2 1 Eukaryotic protein of unknown function (DUF872) DUF4010 PF13194.1 EGC28566.1 - 0.016 14.5 4.9 0.22 10.8 0.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4010) Rhabdo_glycop PF00974.13 EGC28566.1 - 0.033 12.4 0.1 0.32 9.1 0.0 2.0 2 0 0 2 2 2 0 Rhabdovirus spike glycoprotein Hid1 PF12722.2 EGC28566.1 - 0.034 11.8 8.9 0.012 13.3 3.9 1.7 2 0 0 2 2 2 0 High-temperature-induced dauer-formation protein GP41 PF00517.12 EGC28566.1 - 0.038 13.5 1.9 0.38 10.2 0.2 2.7 2 0 0 2 2 2 0 Retroviral envelope protein Orthoreo_P10 PF07204.6 EGC28566.1 - 0.048 13.3 0.0 0.15 11.8 0.0 1.8 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 DUF1049 PF06305.6 EGC28566.1 - 0.05 13.0 0.0 0.05 13.0 0.0 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) EphA2_TM PF14575.1 EGC28566.1 - 0.073 13.4 0.1 0.073 13.4 0.0 3.6 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain WBP-1 PF11669.3 EGC28566.1 - 0.32 11.0 4.2 0.35 10.9 0.1 2.6 3 0 0 3 3 3 0 WW domain-binding protein 1 DUF805 PF05656.9 EGC28566.1 - 0.53 10.1 9.9 3.8 7.3 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF805) Rifin_STEVOR PF02009.11 EGC28566.1 - 1.7 8.2 7.2 0.073 12.6 0.8 1.7 2 0 0 2 2 2 0 Rifin/stevor family DUF912 PF06024.7 EGC28566.1 - 3.8 7.6 14.1 1.1 9.3 0.1 4.2 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FixQ PF05545.6 EGC28566.1 - 5 6.8 6.4 95 2.7 0.2 3.8 3 0 0 3 3 3 0 Cbb3-type cytochrome oxidase component FixQ Fe-ADH PF00465.14 EGC28567.1 - 6.2e-93 311.3 0.0 7.8e-93 311.0 0.0 1.0 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGC28567.1 - 4.3e-07 29.4 0.0 0.00012 21.5 0.0 2.2 2 0 0 2 2 2 2 Iron-containing alcohol dehydrogenase TSNR_N PF04705.7 EGC28567.1 - 0.01 15.6 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 Thiostrepton-resistance methylase, N terminus FNIP PF05725.7 EGC28568.1 - 1.3e-36 124.2 61.3 5e-05 23.1 0.9 12.5 6 2 7 14 14 14 13 FNIP Repeat DUF2523 PF10734.4 EGC28568.1 - 0.022 14.9 0.0 28 5.0 0.0 4.7 7 0 0 7 7 7 0 Protein of unknown function (DUF2523) Tubulin-binding PF00418.14 EGC28568.1 - 1.3 8.7 6.6 3.1e+02 1.1 0.0 6.1 8 0 0 8 8 8 0 Tau and MAP protein, tubulin-binding repeat Aminotran_1_2 PF00155.16 EGC28569.1 - 2.5e-15 56.3 0.0 2.8e-15 56.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II NodZ PF05830.6 EGC28569.1 - 0.11 11.0 0.0 0.14 10.6 0.0 1.1 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) PIG-P PF08510.7 EGC28570.1 - 2e-36 124.4 5.4 2.8e-36 123.9 3.8 1.2 1 0 0 1 1 1 1 PIG-P DUF1279 PF06916.8 EGC28570.1 - 0.0091 16.2 0.7 0.015 15.5 0.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) DUF3377 PF11857.3 EGC28570.1 - 0.33 10.6 1.8 0.51 9.9 1.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) FtsX PF02687.16 EGC28570.1 - 1.1 9.0 6.3 1.5 8.5 4.4 1.1 1 0 0 1 1 1 0 FtsX-like permease family SieB PF14163.1 EGC28570.1 - 2.4 7.7 5.2 3.4 7.2 3.6 1.3 1 1 0 1 1 1 0 Superinfection exclusion protein B Adeno_E3_14_5 PF04834.7 EGC28570.1 - 4 7.9 5.9 0.48 10.8 1.2 1.7 2 1 0 2 2 2 0 Early E3 14.5 kDa protein DPM2 PF07297.7 EGC28570.1 - 4.1 7.7 9.3 5.6 7.3 6.4 1.2 1 0 0 1 1 1 0 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) MARVEL PF01284.18 EGC28570.1 - 9.6 6.0 8.5 6.9 6.4 4.2 1.7 1 1 1 2 2 2 0 Membrane-associating domain P2X_receptor PF00864.14 EGC28571.1 - 2.3e-13 49.6 3.1 2.7e-08 32.9 0.5 3.1 1 1 1 2 2 2 2 ATP P2X receptor ELO PF01151.13 EGC28573.1 - 1.2e-62 211.4 30.3 1.4e-62 211.2 21.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family Spy1 PF11357.3 EGC28574.1 - 1.2e-08 35.0 7.7 3.2e-07 30.4 2.6 2.7 2 1 0 2 2 2 1 Cell cycle regulatory protein Sugar_transport PF06800.7 EGC28574.1 - 0.069 12.2 0.0 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 Sugar transport protein DUF4500 PF14937.1 EGC28575.1 - 0.014 15.1 1.2 0.14 12.0 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4500) TIG PF01833.19 EGC28576.1 - 0.0017 18.2 0.3 0.0017 18.2 0.2 4.7 3 1 2 5 5 5 1 IPT/TIG domain Laminin_EGF PF00053.19 EGC28576.1 - 0.0086 15.9 7.7 0.0086 15.9 5.4 2.9 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC28576.1 - 0.015 15.4 15.0 0.015 15.4 10.4 2.7 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 EGC28576.1 - 4.8 7.4 10.5 0.16 12.1 2.4 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF DDE_3 PF13358.1 EGC28577.1 - 6.6e-13 48.6 0.0 6.6e-13 48.6 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease TPR_2 PF07719.12 EGC28578.1 - 3e-05 23.6 2.9 2.7 8.1 0.2 5.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC28578.1 - 6.1e-05 22.5 6.8 0.0089 15.6 0.1 4.3 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGC28578.1 - 0.064 12.8 13.4 4.5 7.0 0.0 5.1 5 0 0 5 5 5 0 Tetratricopeptide repeat Sel1 PF08238.7 EGC28578.1 - 0.091 13.4 0.8 0.39 11.4 0.0 2.5 2 0 0 2 2 2 0 Sel1 repeat Histone PF00125.19 EGC28579.1 - 4.6e-19 68.3 0.0 5.4e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC28579.1 - 4.1e-05 23.5 0.0 4.9e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUSP PF06337.7 EGC28580.1 - 0.062 13.7 0.3 0.11 12.9 0.2 1.5 1 1 0 1 1 1 0 DUSP domain PIP5K PF01504.13 EGC28582.1 - 9e-24 83.9 6.2 6.4e-23 81.1 4.3 2.4 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Sigma70_ner PF04546.8 EGC28582.1 - 7 6.2 18.5 0.99 8.9 9.2 2.1 3 0 0 3 3 3 0 Sigma-70, non-essential region Mod_r PF07200.8 EGC28583.1 - 0.0087 15.9 6.5 0.012 15.5 4.5 1.2 1 0 0 1 1 1 1 Modifier of rudimentary (Mod(r)) protein Microtub_assoc PF07989.6 EGC28583.1 - 0.037 13.8 4.8 0.065 13.0 3.1 1.6 1 1 0 1 1 1 0 Microtubule associated DUF3972 PF13118.1 EGC28583.1 - 0.05 13.6 4.7 0.096 12.7 3.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3972) Viral_env_E26 PF11050.3 EGC28583.1 - 0.074 12.2 1.6 0.092 11.9 1.1 1.2 1 0 0 1 1 1 0 Virus envelope protein E26 UPF0449 PF15136.1 EGC28583.1 - 0.093 12.9 2.4 0.14 12.3 1.6 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0449 Orthopox_F6 PF06601.7 EGC28583.1 - 0.11 12.4 1.9 0.15 12.0 0.5 1.8 1 1 0 1 1 1 0 Orthopoxvirus F6 protein Atg14 PF10186.4 EGC28583.1 - 0.23 10.3 4.2 0.24 10.2 2.9 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 SlyX PF04102.7 EGC28583.1 - 0.26 11.6 3.1 0.65 10.4 2.1 1.7 1 0 0 1 1 1 0 SlyX Sigma54_DBD PF04552.8 EGC28583.1 - 0.34 10.4 3.5 0.75 9.2 0.9 2.0 1 1 1 2 2 2 0 Sigma-54, DNA binding domain IFP_35_N PF07334.8 EGC28583.1 - 0.46 10.5 8.1 0.8 9.7 5.0 1.9 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus TcdB_N PF12918.2 EGC28583.1 - 2.8 8.0 9.5 0.87 9.7 3.5 2.3 3 0 0 3 3 3 0 TcdB toxin N-terminal helical domain AAA_23 PF13476.1 EGC28583.1 - 3.2 8.0 14.8 3.6 7.8 10.2 1.0 1 0 0 1 1 1 0 AAA domain FANCAA PF15146.1 EGC28584.1 - 0.0062 15.5 0.0 0.01 14.7 0.0 1.3 1 0 0 1 1 1 1 Fanconi anemia-associated FNIP PF05725.7 EGC28585.1 - 1.5e-27 95.2 14.6 1.2e-09 37.9 2.7 4.5 3 1 1 4 4 4 4 FNIP Repeat LRR_5 PF13306.1 EGC28585.1 - 2.1e-06 27.4 0.3 0.0011 18.6 0.1 2.8 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) ATP-synt_G PF04718.10 EGC28586.1 - 0.022 15.3 1.1 0.022 15.3 0.8 3.3 2 1 1 3 3 3 0 Mitochondrial ATP synthase g subunit THRAP3_BCLAF1 PF15440.1 EGC28586.1 - 8.6 4.8 46.3 11 4.5 32.1 1.0 1 0 0 1 1 1 0 THRAP3/BCLAF1 family WD40 PF00400.27 EGC28588.1 - 6.7e-70 228.6 35.4 2.6e-09 36.6 0.1 12.0 13 0 0 13 13 13 10 WD domain, G-beta repeat Utp12 PF04003.7 EGC28588.1 - 2.3e-19 69.3 0.0 3.9e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family Nup160 PF11715.3 EGC28588.1 - 0.00027 19.2 1.5 0.0037 15.4 0.1 3.2 3 0 0 3 3 3 1 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGC28588.1 - 0.003 16.3 21.6 0.16 10.6 3.6 5.3 1 1 3 5 5 5 3 Nup133 N terminal like Nbas_N PF15492.1 EGC28588.1 - 0.02 14.0 0.0 3.7 6.5 0.0 2.6 1 1 0 2 2 2 0 Neuroblastoma-amplified sequence, N terminal Apc4_WD40 PF12894.2 EGC28588.1 - 0.061 12.8 0.0 5.4 6.5 0.0 3.6 3 1 1 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain FNIP PF05725.7 EGC28589.1 - 1.2e-23 82.7 2.6 5.1e-12 45.5 0.6 2.0 2 0 0 2 2 2 2 FNIP Repeat DUF1769 PF08588.5 EGC28589.1 - 0.016 15.1 1.7 7.2 6.6 0.0 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF1769) Med21 PF11221.3 EGC28590.1 - 6.9e-13 48.7 5.1 6.9e-13 48.7 3.6 2.8 1 1 1 2 2 2 1 Subunit 21 of Mediator complex DUF2452 PF10504.4 EGC28590.1 - 0.0091 15.2 0.3 0.012 14.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2452) Kinase-PPPase PF03618.9 EGC28590.1 - 0.019 14.4 0.5 0.028 13.9 0.2 1.4 1 1 0 1 1 1 0 Kinase/pyrophosphorylase Arena_nucleocap PF00843.12 EGC28590.1 - 0.077 10.8 1.8 0.089 10.6 1.2 1.0 1 0 0 1 1 1 0 Arenavirus nucleocapsid protein IncA PF04156.9 EGC28590.1 - 0.1 12.1 3.5 0.13 11.8 2.4 1.2 1 0 0 1 1 1 0 IncA protein Iron_permease PF04120.7 EGC28590.1 - 8.1 6.0 8.3 10 5.7 5.1 1.6 2 0 0 2 2 2 0 Low affinity iron permease zf-Nse PF11789.3 EGC28591.1 - 1.2e-17 63.1 0.5 2.1e-17 62.3 0.3 1.4 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGC28591.1 - 1.9e-06 27.4 0.5 4.4e-06 26.3 0.3 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EGC28591.1 - 0.0041 16.6 0.7 0.0072 15.8 0.5 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-C3HC4_4 PF15227.1 EGC28591.1 - 0.0063 16.3 0.1 0.012 15.4 0.1 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGC28591.1 - 0.07 12.9 0.5 0.12 12.1 0.4 1.4 1 0 0 1 1 1 0 Ring finger domain zf-C3HC4 PF00097.20 EGC28591.1 - 0.13 11.9 0.9 0.2 11.3 0.1 1.7 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28591.1 - 0.19 11.7 0.9 0.39 10.7 0.6 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DAGK_cat PF00781.19 EGC28592.1 - 1.2e-15 57.1 0.0 2.4e-15 56.1 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain VPS9 PF02204.13 EGC28595.1 - 2.2e-22 79.0 0.2 9e-22 77.0 0.1 2.2 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain CUE PF02845.11 EGC28595.1 - 0.0021 17.5 0.0 0.006 16.0 0.0 1.9 1 0 0 1 1 1 1 CUE domain WD40 PF00400.27 EGC28596.1 - 4.5e-14 51.6 12.8 1.9e-06 27.5 0.3 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat PD40 PF07676.7 EGC28596.1 - 0.0088 15.6 0.1 1.1 8.9 0.0 3.5 3 0 0 3 3 3 1 WD40-like Beta Propeller Repeat eIF2A PF08662.6 EGC28596.1 - 0.4 10.3 5.0 2.1 8.0 0.0 3.7 3 1 2 5 5 5 0 Eukaryotic translation initiation factor eIF2A zf-NADH-PPase PF09297.6 EGC28597.1 - 0.097 12.2 0.4 0.15 11.5 0.2 1.3 1 0 0 1 1 1 0 NADH pyrophosphatase zinc ribbon domain DUF3439 PF11921.3 EGC28598.1 - 7.9 6.2 11.0 0.12 12.1 1.5 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Glyco_hydro_18 PF00704.23 EGC28599.1 - 1.5e-40 139.7 1.3 1.9e-40 139.3 0.9 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TolB_N PF04052.8 EGC28599.1 - 0.0093 16.0 0.0 0.032 14.3 0.0 1.9 2 0 0 2 2 2 1 TolB amino-terminal domain RAMPs PF03787.10 EGC28600.1 - 0.43 10.3 7.8 5.8 6.6 0.1 2.3 2 0 0 2 2 2 0 RAMP superfamily Conotoxin PF02950.12 EGC28600.1 - 1.3 9.8 4.7 44 4.9 0.0 3.2 2 0 0 2 2 2 0 Conotoxin DUF1980 PF09323.5 EGC28600.1 - 2.5 7.8 17.0 0.052 13.2 1.9 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF1980) DUF1387 PF07139.6 EGC28600.1 - 5.1 6.6 18.2 0.021 14.4 6.1 1.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1387) FtsX PF02687.16 EGC28601.1 - 4.2e-27 94.3 30.7 1.9e-16 59.9 7.6 4.4 4 1 0 4 4 4 2 FtsX-like permease family TGT PF01702.13 EGC28602.1 - 3.5e-91 304.7 0.0 4.6e-91 304.3 0.0 1.1 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Isochorismatase PF00857.15 EGC28603.1 - 5.3e-37 127.4 0.1 6.1e-37 127.2 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 EGC28604.1 - 7.7e-43 146.4 0.7 8.8e-43 146.2 0.5 1.0 1 0 0 1 1 1 1 Isochorismatase family DUF1694 PF07997.6 EGC28604.1 - 0.04 13.8 0.1 0.098 12.5 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1694) Cloacin_immun PF03513.9 EGC28604.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Cloacin immunity protein DEAD PF00270.24 EGC28605.1 - 5.4e-43 146.4 0.2 7.7e-43 145.9 0.1 1.2 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC28605.1 - 3.4e-24 84.4 0.2 6.8e-24 83.5 0.1 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC28605.1 - 0.0012 18.7 0.0 0.0066 16.2 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit Herpes_ORF11 PF04797.8 EGC28606.1 - 0.0098 14.3 2.2 0.057 11.8 0.8 2.0 1 1 1 2 2 2 2 Herpesvirus dUTPase protein UBN2 PF14223.1 EGC28606.1 - 0.068 12.9 0.7 3 7.6 0.0 2.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type FNIP PF05725.7 EGC28609.1 - 4.8e-82 269.6 32.0 3.4e-15 55.7 0.5 7.9 5 1 4 9 9 9 9 FNIP Repeat DUF3439 PF11921.3 EGC28610.1 - 0.0078 15.9 2.9 0.013 15.2 2.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Gly-zipper_OmpA PF13436.1 EGC28612.1 - 0.077 12.6 8.0 0.15 11.7 5.5 1.4 1 0 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain DUF1777 PF08648.7 EGC28613.1 - 0.089 12.5 43.1 0.096 12.4 29.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EGC28613.1 - 0.31 11.5 43.0 0.48 10.9 29.8 1.4 1 1 0 1 1 1 0 Pre-mRNA-splicing factor 38-associated hydrophilic C-term SNARE_assoc PF09335.6 EGC28616.1 - 0.0036 17.4 0.2 0.017 15.3 0.1 1.9 2 0 0 2 2 2 1 SNARE associated Golgi protein CAAD PF14159.1 EGC28616.1 - 0.043 13.4 0.2 0.092 12.3 0.2 1.6 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2217 PF10265.4 EGC28616.1 - 2.1 6.9 6.7 2.3 6.8 4.6 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) NmrA PF05368.8 EGC28617.1 - 1.6e-28 99.5 1.2 9e-21 74.1 0.1 2.2 1 1 1 2 2 2 2 NmrA-like family NmrA PF05368.8 EGC28618.1 - 9.5e-56 188.6 0.1 2e-55 187.6 0.0 1.5 2 0 0 2 2 2 1 NmrA-like family Ribosomal_S25 PF03297.10 EGC28618.1 - 1.3e-38 131.2 4.4 2.1e-38 130.5 3.1 1.3 1 0 0 1 1 1 1 S25 ribosomal protein NAD_binding_10 PF13460.1 EGC28618.1 - 5.3e-14 52.6 0.0 2.9e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGC28618.1 - 4.3e-06 26.3 0.0 1e-05 25.1 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC28618.1 - 7.3e-05 21.5 0.1 0.00018 20.3 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family HTH_24 PF13412.1 EGC28618.1 - 0.0014 17.9 0.3 0.0064 15.8 0.4 1.9 2 0 0 2 2 2 1 Winged helix-turn-helix DNA-binding TrmB PF01978.14 EGC28618.1 - 0.015 14.9 0.4 0.04 13.6 0.1 1.8 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB F420_oxidored PF03807.12 EGC28618.1 - 0.018 15.4 0.0 0.058 13.8 0.0 1.9 1 1 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent KR PF08659.5 EGC28618.1 - 0.027 14.1 0.1 0.062 12.9 0.0 1.7 1 1 0 1 1 1 0 KR domain adh_short PF00106.20 EGC28618.1 - 0.042 13.7 0.0 0.11 12.4 0.0 1.7 1 0 0 1 1 1 0 short chain dehydrogenase DUF505 PF04458.7 EGC28618.1 - 0.066 11.3 0.0 0.087 10.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF505) Fe_dep_repress PF01325.14 EGC28618.1 - 0.11 12.4 0.1 0.22 11.4 0.0 1.4 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Abhydro_lipase PF04083.11 EGC28620.1 - 2.9e-20 71.3 0.2 1.7e-18 65.7 0.0 2.7 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_6 PF12697.2 EGC28620.1 - 3.7e-05 23.7 0.0 9.9e-05 22.3 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC28620.1 - 5.7e-05 22.9 0.0 0.00028 20.6 0.0 2.2 1 1 0 1 1 1 1 Alpha/beta hydrolase family Herpes_capsid PF06112.6 EGC28620.1 - 0.0058 16.6 19.0 0.015 15.3 4.6 2.5 2 0 0 2 2 2 2 Gammaherpesvirus capsid protein DUF3439 PF11921.3 EGC28620.1 - 7.4 6.3 11.8 2.4 7.9 3.2 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) FNIP PF05725.7 EGC28621.1 - 0.0011 18.8 1.2 0.0031 17.4 0.9 1.8 1 0 0 1 1 1 1 FNIP Repeat ETF_QO PF05187.8 EGC28623.1 - 0.059 13.3 0.0 5 7.1 0.0 2.7 2 0 0 2 2 2 0 Electron transfer flavoprotein-ubiquinone oxidoreductase SET PF00856.23 EGC28624.1 - 4.1e-13 49.9 1.5 1.2e-12 48.4 0.0 2.3 2 1 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGC28624.1 - 6.9e-06 25.8 6.7 6.9e-06 25.8 4.6 2.0 2 0 0 2 2 2 1 MYND finger Ecl1 PF12855.2 EGC28624.1 - 0.33 10.2 4.7 1 8.6 3.3 2.0 1 0 0 1 1 1 0 Life-span regulatory factor CpXC PF14353.1 EGC28624.1 - 0.89 9.5 0.0 0.89 9.5 0.0 3.8 3 1 1 4 4 4 0 CpXC protein ATG16 PF08614.6 EGC28625.1 - 0.0069 16.2 12.4 0.0085 15.9 8.6 1.1 1 0 0 1 1 1 1 Autophagy protein 16 (ATG16) RNA_pol_Rpb5_N PF03871.9 EGC28625.1 - 0.014 15.8 0.6 0.017 15.5 0.4 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain ERK-JNK_inhib PF15002.1 EGC28625.1 - 0.046 13.1 9.4 0.053 12.8 6.5 1.3 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor Apc1 PF12859.2 EGC28625.1 - 0.13 12.5 0.3 0.14 12.3 0.2 1.1 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 1 CWC25 PF12542.3 EGC28625.1 - 0.17 12.3 11.7 0.2 12.1 8.1 1.1 1 0 0 1 1 1 0 Pre-mRNA splicing factor DUF342 PF03961.8 EGC28625.1 - 0.31 9.4 11.5 0.34 9.2 8.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Val_tRNA-synt_C PF10458.4 EGC28625.1 - 0.44 10.6 15.7 1.2 9.2 8.8 2.8 1 1 1 2 2 2 0 Valyl tRNA synthetase tRNA binding arm Vasohibin PF14822.1 EGC28625.1 - 0.45 9.5 3.2 0.47 9.4 2.2 1.2 1 0 0 1 1 1 0 Vasohibin AAA_23 PF13476.1 EGC28625.1 - 0.58 10.4 13.5 0.76 10.0 9.4 1.2 1 0 0 1 1 1 0 AAA domain TSA PF03249.8 EGC28625.1 - 0.77 8.2 5.7 0.77 8.2 4.0 1.0 1 0 0 1 1 1 0 Type specific antigen RR_TM4-6 PF06459.7 EGC28625.1 - 0.98 9.2 11.2 1 9.2 7.7 1.0 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Bap31 PF05529.7 EGC28625.1 - 3 7.2 12.0 3.8 6.9 8.3 1.3 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like EIIBC-GUT_N PF03612.9 EGC28625.1 - 3.7 7.1 5.2 4.8 6.7 3.6 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus tRNA-synt_His PF13393.1 EGC28625.1 - 3.9 6.4 6.4 4.3 6.2 4.4 1.0 1 0 0 1 1 1 0 Histidyl-tRNA synthetase V_ATPase_I PF01496.14 EGC28625.1 - 5.2 4.8 8.9 5.6 4.6 6.2 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IATP PF04568.7 EGC28625.1 - 7.9 6.5 18.3 0.6 10.1 7.6 2.2 1 1 2 3 3 3 0 Mitochondrial ATPase inhibitor, IATP Neur_chan_memb PF02932.11 EGC28625.1 - 9.3 6.0 6.3 9.7 5.9 4.3 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4407 PF14362.1 EGC28625.1 - 9.6 5.0 13.3 7.9 5.3 7.7 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) eIF-1a PF01176.14 EGC28627.1 - 3.7e-12 45.4 0.8 5.8e-12 44.8 0.6 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 DDE_Tnp_4 PF13359.1 EGC28627.1 - 0.008 15.7 0.2 0.0099 15.4 0.2 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease CSD PF00313.17 EGC28628.1 - 0.13 12.0 0.2 20 5.0 0.2 2.9 2 0 0 2 2 2 0 'Cold-shock' DNA-binding domain CarboxypepD_reg PF13620.1 EGC28629.1 - 7.2e-12 45.1 2.5 0.00095 19.1 0.1 4.6 4 0 0 4 4 4 3 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EGC28629.1 - 1.8e-09 37.1 8.6 0.052 13.3 0.9 4.5 4 0 0 4 4 4 3 Cna protein B-type domain DUF4480 PF13715.1 EGC28629.1 - 3.6e-05 23.7 0.0 1 9.4 0.0 3.8 3 0 0 3 3 3 2 Domain of unknown function (DUF4480) DUF2012 PF09430.5 EGC28629.1 - 0.12 12.1 0.2 1.5 8.6 0.0 2.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2012) MDM31_MDM32 PF08118.6 EGC28630.1 - 0.002 16.6 0.4 0.0022 16.5 0.3 1.0 1 0 0 1 1 1 1 Yeast mitochondrial distribution and morphology (MDM) proteins Apis_Csd PF11671.3 EGC28630.1 - 7.2 6.3 11.6 7.8 6.2 8.1 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein SCO1-SenC PF02630.9 EGC28631.1 - 1.6e-51 174.3 0.0 1.6e-51 174.3 0.0 2.1 2 0 0 2 2 2 1 SCO1/SenC Thioredoxin_8 PF13905.1 EGC28631.1 - 6.5e-05 22.9 0.5 0.00025 21.1 0.0 2.3 2 1 0 2 2 2 1 Thioredoxin-like AhpC-TSA PF00578.16 EGC28631.1 - 8.7e-05 22.2 0.0 0.00023 20.8 0.0 1.8 1 1 0 1 1 1 1 AhpC/TSA family DUF4642 PF15484.1 EGC28631.1 - 0.051 13.5 7.0 0.1 12.5 4.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4642) DUF2407_C PF13373.1 EGC28631.1 - 0.071 13.0 3.2 0.15 11.9 2.2 1.5 1 0 0 1 1 1 0 DUF2407 C-terminal domain LMBR1 PF04791.11 EGC28631.1 - 0.091 11.3 3.3 0.13 10.8 2.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Herpes_env PF01673.13 EGC28631.1 - 0.41 9.1 4.4 0.69 8.4 3.0 1.3 1 0 0 1 1 1 0 Herpesvirus putative major envelope glycoprotein Serinc PF03348.10 EGC28631.1 - 0.52 8.9 4.6 0.66 8.6 3.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) Folate_carrier PF01770.13 EGC28631.1 - 0.65 8.4 5.9 0.93 7.9 4.1 1.1 1 0 0 1 1 1 0 Reduced folate carrier Med3 PF11593.3 EGC28631.1 - 7.6 5.6 22.6 14 4.7 15.5 1.5 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal PP2C_C PF07830.8 EGC28632.1 - 0.11 12.6 0.3 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Secretin_N_2 PF07655.8 EGC28632.1 - 1.2 9.5 17.6 8.9 6.7 9.4 2.3 2 0 0 2 2 2 0 Secretin N-terminal domain Di19_C PF14571.1 EGC28632.1 - 1.4 9.2 7.7 0.62 10.4 1.3 2.4 2 1 0 2 2 2 0 Stress-induced protein Di19, C-terminal FKS1_dom1 PF14288.1 EGC28632.1 - 2.4 8.0 6.2 1.7 8.6 0.2 2.5 1 1 2 3 3 3 0 1,3-beta-glucan synthase subunit FKS1, domain-1 Arf PF00025.16 EGC28633.1 - 1.1e-61 207.0 1.4 3e-59 199.1 1.0 2.0 1 1 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGC28633.1 - 8.2e-11 41.2 3.0 1e-05 24.4 0.1 2.1 1 1 1 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGC28633.1 - 2.1e-09 36.9 0.0 7e-08 32.0 0.0 2.0 1 1 1 2 2 2 1 Ras family Gtr1_RagA PF04670.7 EGC28633.1 - 3.2e-09 36.2 0.0 4.3e-09 35.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC28633.1 - 1e-07 32.4 0.0 1.4e-07 32.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC28633.1 - 1.9e-07 31.0 0.0 2.3e-07 30.7 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC28633.1 - 1.6e-06 27.4 0.0 4.3e-06 26.0 0.0 1.5 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGC28633.1 - 0.026 13.7 0.3 0.13 11.5 0.2 2.0 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC28633.1 - 0.053 13.0 0.1 0.13 11.7 0.1 1.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation GTP_EFTU PF00009.22 EGC28633.1 - 0.14 11.5 0.0 14 5.1 0.0 2.7 1 1 1 2 2 2 0 Elongation factor Tu GTP binding domain RAB3GAP2_N PF14655.1 EGC28634.1 - 2e-141 471.8 0.2 2.5e-141 471.4 0.2 1.1 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus DUF3473 PF11959.3 EGC28634.1 - 0.028 13.8 0.0 0.071 12.5 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3473) CIAPIN1 PF05093.8 EGC28634.1 - 1.5 8.9 5.1 3.1 7.9 0.3 2.6 2 0 0 2 2 2 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis RNase_T PF00929.19 EGC28635.1 - 0.0024 18.1 1.2 0.0029 17.9 0.1 1.7 2 0 0 2 2 2 1 Exonuclease eIF-6 PF01912.13 EGC28635.1 - 0.0047 16.0 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 eIF-6 family DUF4653 PF15546.1 EGC28635.1 - 0.013 14.8 2.3 0.016 14.5 1.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4653) DUF3244 PF11589.3 EGC28635.1 - 0.023 14.3 0.2 0.054 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) GvpK PF05121.7 EGC28635.1 - 0.084 12.7 0.1 12 5.7 0.0 2.3 2 0 0 2 2 2 0 Gas vesicle protein K DNA_pol_A_exo1 PF01612.15 EGC28635.1 - 0.11 11.9 2.7 0.22 10.9 0.1 2.3 1 1 1 3 3 3 0 3'-5' exonuclease ATP-synt_E PF05680.7 EGC28635.1 - 0.52 10.3 5.5 0.93 9.4 3.5 1.7 1 1 0 1 1 1 0 ATP synthase E chain Phosphodiest PF01663.17 EGC28636.1 - 1.7e-06 27.6 0.1 3e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Renin_r PF07850.9 EGC28636.1 - 0.042 14.1 0.7 0.18 12.1 0.1 2.3 2 0 0 2 2 2 0 Renin receptor-like protein RRM_1 PF00076.17 EGC28637.1 - 3.2e-14 52.3 0.4 8.1e-14 51.0 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC28637.1 - 4.1e-14 52.3 0.0 1e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC28637.1 - 3.8e-11 42.6 0.1 8.4e-11 41.5 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) OATP PF03137.15 EGC28637.1 - 0.069 11.1 1.0 0.12 10.4 0.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family CENP-I PF07778.6 EGC28638.1 - 2.2e-32 111.9 33.0 1.2e-16 59.9 5.3 3.0 1 1 2 3 3 3 2 Mis6 DSPc PF00782.15 EGC28639.1 - 2.8e-34 117.5 0.1 2.8e-34 117.5 0.1 3.9 4 1 1 5 5 5 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC28639.1 - 6.2e-07 28.9 0.3 6.2e-07 28.9 0.2 2.2 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGC28639.1 - 0.0047 16.9 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 Inositol hexakisphosphate NTP_transferase PF00483.18 EGC28640.1 - 8.1e-28 97.3 0.0 1e-27 97.0 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase NTP_transf_3 PF12804.2 EGC28640.1 - 8.9e-06 25.8 0.0 1.2e-05 25.4 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep PF00132.19 EGC28640.1 - 1.3e-05 24.4 1.0 1.3e-05 24.4 0.7 3.2 3 1 1 4 4 4 1 Bacterial transferase hexapeptide (six repeats) CTP_transf_3 PF02348.14 EGC28640.1 - 0.022 14.3 0.1 0.05 13.2 0.1 1.6 1 0 0 1 1 1 0 Cytidylyltransferase IspD PF01128.14 EGC28640.1 - 0.11 12.0 0.0 0.21 11.0 0.0 1.5 1 0 0 1 1 1 0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase ATP-synt_F PF01990.12 EGC28641.1 - 2.7e-33 114.2 0.7 3.1e-33 114.0 0.5 1.1 1 0 0 1 1 1 1 ATP synthase (F/14-kDa) subunit DXP_synthase_N PF13292.1 EGC28641.1 - 0.09 11.6 0.1 0.096 11.6 0.1 1.1 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase UPF0183 PF03676.9 EGC28642.1 - 1.1e-98 330.4 11.9 1.2e-48 165.7 0.2 3.1 1 1 0 2 2 2 2 Uncharacterised protein family (UPF0183) HTH_3 PF01381.17 EGC28642.1 - 0.11 12.3 0.0 0.32 10.8 0.0 1.7 1 0 0 1 1 1 0 Helix-turn-helix Pex14_N PF04695.8 EGC28642.1 - 4.4 7.3 15.8 0.5 10.4 3.5 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pyridoxal_deC PF00282.14 EGC28643.1 - 1.2e-73 247.7 0.0 1.5e-73 247.3 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain 2OG-FeII_Oxy_3 PF13640.1 EGC28644.1 - 2.3e-09 37.6 0.0 4e-09 36.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 EGC28644.1 - 8.6e-07 28.0 0.1 1e-06 27.7 0.1 1.1 1 0 0 1 1 1 1 Poxvirus C4/C10 protein 2OG-FeII_Oxy_4 PF13661.1 EGC28644.1 - 0.00035 20.1 0.0 0.00068 19.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 EGC28644.1 - 0.011 15.7 0.0 1.1 9.2 0.0 2.4 1 1 1 2 2 2 0 Phytanoyl-CoA dioxygenase (PhyH) 2OG-FeII_Oxy_5 PF13759.1 EGC28644.1 - 0.096 12.9 0.0 0.35 11.1 0.0 2.0 2 0 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase zf-RING_2 PF13639.1 EGC28645.1 - 2.3e-10 40.1 11.9 4.3e-10 39.2 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC28645.1 - 8.4e-07 28.5 8.1 1.4e-06 27.8 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC28645.1 - 1.3e-06 28.4 6.1 2.9e-06 27.2 4.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC28645.1 - 2.4e-06 27.1 14.4 5.3e-06 25.9 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28645.1 - 3.5e-06 26.9 13.8 6.7e-06 26.0 9.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC28645.1 - 0.0006 19.4 13.0 0.0006 19.4 9.0 1.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC28645.1 - 0.0034 17.2 3.8 0.0071 16.1 2.6 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC28645.1 - 0.046 13.6 13.4 0.12 12.2 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC28645.1 - 1.3 8.8 8.1 6.9 6.4 5.6 2.4 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC28645.1 - 2 8.3 8.6 4.5 7.1 6.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Rep_fac_C PF08542.6 EGC28646.1 - 4.1e-16 58.7 0.2 9.4e-16 57.5 0.0 1.7 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGC28646.1 - 2.2e-14 53.4 0.0 1.8e-13 50.4 0.0 2.3 1 1 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGC28646.1 - 3.8e-14 53.0 0.0 6.4e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rad17 PF03215.10 EGC28646.1 - 7.6e-11 41.3 0.1 5.5e-08 31.9 0.0 2.2 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_22 PF13401.1 EGC28646.1 - 8.8e-06 25.8 0.0 4.1e-05 23.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGC28646.1 - 1.4e-05 24.8 0.0 2.5e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC28646.1 - 2.5e-05 23.9 0.0 5.2e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain RuvB_N PF05496.7 EGC28646.1 - 3e-05 23.1 0.0 4.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGC28646.1 - 6e-05 23.1 0.1 0.0016 18.4 0.0 2.2 1 1 0 2 2 2 1 AAA ATPase domain ResIII PF04851.10 EGC28646.1 - 0.00022 21.1 0.0 0.023 14.5 0.0 2.6 2 1 1 3 3 3 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EGC28646.1 - 0.00024 20.3 0.0 0.0047 16.1 0.0 2.3 1 1 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGC28646.1 - 0.00081 19.2 0.0 0.0018 18.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EGC28646.1 - 0.002 17.6 0.1 0.031 13.7 0.0 2.2 1 1 1 2 2 2 1 DEAD/DEAH box helicase AAA_24 PF13479.1 EGC28646.1 - 0.0021 17.7 0.4 0.0059 16.2 0.3 1.8 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EGC28646.1 - 0.0038 16.8 0.1 0.009 15.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGC28646.1 - 0.0096 15.3 0.0 0.021 14.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGC28646.1 - 0.014 14.8 0.1 0.52 9.6 0.0 2.8 1 1 0 1 1 1 0 AAA-like domain PhoH PF02562.11 EGC28646.1 - 0.015 14.5 0.0 1.2 8.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein AAA_5 PF07728.9 EGC28646.1 - 0.022 14.4 0.2 0.11 12.2 0.1 2.1 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EGC28646.1 - 0.032 13.2 0.0 0.067 12.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) IstB_IS21 PF01695.12 EGC28646.1 - 0.04 13.3 0.0 0.41 10.0 0.0 2.1 2 0 0 2 2 2 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EGC28646.1 - 0.11 11.9 0.0 0.32 10.4 0.0 1.7 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_23 PF13476.1 EGC28646.1 - 0.16 12.3 5.1 0.49 10.6 3.6 1.8 1 1 0 1 1 1 0 AAA domain Nop14 PF04147.7 EGC28647.1 - 0.092 10.6 22.1 0.13 10.1 15.3 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGC28647.1 - 0.24 9.4 11.1 0.32 8.9 7.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Astro_capsid PF03115.9 EGC28647.1 - 0.5 8.5 6.1 0.63 8.2 4.2 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Vfa1 PF08432.5 EGC28647.1 - 1.8 8.5 14.7 3.1 7.7 10.2 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Daxx PF03344.10 EGC28647.1 - 4.7 5.5 22.6 6.8 5.0 15.6 1.1 1 0 0 1 1 1 0 Daxx Family Tantalus PF15386.1 EGC28650.1 - 0.18 11.5 1.2 0.22 11.3 0.9 1.3 1 1 0 1 1 1 0 Drosophila Tantalus-like Histone PF00125.19 EGC28651.1 - 0.00017 21.6 0.1 0.0048 17.0 0.0 2.3 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 TFIID-18kDa PF02269.11 EGC28651.1 - 0.36 10.6 3.3 1.8 8.4 0.0 2.6 3 0 0 3 3 3 0 Transcription initiation factor IID, 18kD subunit Arb2 PF09757.4 EGC28652.1 - 1.4e-21 76.7 3.6 4.1e-21 75.2 2.5 1.8 1 1 0 1 1 1 1 Arb2 domain Abhydrolase_1 PF00561.15 EGC28652.1 - 0.0003 20.4 0.4 0.0028 17.2 0.0 2.4 2 1 1 3 3 3 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC28652.1 - 0.0022 17.9 0.0 0.0032 17.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EGC28652.1 - 0.004 16.3 0.1 0.01 15.0 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 EGC28652.1 - 0.0082 15.9 0.0 0.011 15.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ser_hydrolase PF06821.8 EGC28652.1 - 0.015 14.8 0.0 0.024 14.2 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase DUF900 PF05990.7 EGC28652.1 - 0.042 13.1 0.0 0.067 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) PGAP1 PF07819.8 EGC28652.1 - 0.084 12.4 0.8 0.14 11.7 0.0 1.7 2 0 0 2 2 2 0 PGAP1-like protein Sec7 PF01369.15 EGC28653.1 - 5.6e-53 179.4 3.9 5.6e-53 179.4 2.7 2.4 2 0 0 2 2 2 1 Sec7 domain Sec7_N PF12783.2 EGC28653.1 - 1.8e-38 131.6 6.2 1.8e-38 131.6 4.3 6.4 8 0 0 8 8 8 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGC28653.1 - 1.9e-24 84.9 12.8 2.1e-24 84.8 0.2 6.0 6 0 0 6 6 6 1 Domain of unknown function (DUF1981) HEAT PF02985.17 EGC28653.1 - 0.00056 19.7 0.3 71 3.8 0.0 5.7 5 0 0 5 5 5 0 HEAT repeat CH PF00307.26 EGC28654.1 - 5.8e-30 103.5 24.1 7.5e-13 48.4 0.0 6.8 5 2 1 6 6 6 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC28654.1 - 2.7e-07 30.1 2.3 0.08 12.6 0.0 5.3 4 0 0 4 4 4 3 CAMSAP CH domain LPP PF04728.8 EGC28654.1 - 2.5 7.9 11.4 0.04 13.6 0.3 3.6 4 0 0 4 4 4 0 Lipoprotein leucine-zipper zf-C3HC4_2 PF13923.1 EGC28655.1 - 3.6e-09 36.4 13.0 7.4e-09 35.4 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28655.1 - 9.9e-09 34.7 12.4 2.6e-08 33.3 8.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC28655.1 - 6.8e-08 32.0 7.4 1.2e-07 31.2 5.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC28655.1 - 4.2e-06 26.4 11.1 8.5e-06 25.5 7.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC28655.1 - 4.6e-05 23.0 10.1 0.00012 21.7 7.0 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC28655.1 - 0.0066 16.2 12.5 0.017 14.9 8.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC28655.1 - 0.044 13.3 5.0 0.13 11.8 3.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGC28655.1 - 0.096 12.4 2.4 0.22 11.3 1.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Mucin PF01456.12 EGC28655.1 - 0.58 9.9 16.9 1.2 8.8 11.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-rbx1 PF12678.2 EGC28655.1 - 0.82 9.8 8.4 3.2 7.9 5.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC28655.1 - 1.4 8.6 13.3 0.58 9.9 6.3 2.6 2 0 0 2 2 2 0 RING-type zinc-finger Arm PF00514.18 EGC28657.1 - 2e-19 68.6 0.6 0.01 15.6 0.0 7.4 7 0 0 7 7 7 5 Armadillo/beta-catenin-like repeat Atx10homo_assoc PF09759.4 EGC28657.1 - 9e-11 41.4 0.3 0.13 11.9 0.0 4.9 1 1 5 6 6 6 4 Spinocerebellar ataxia type 10 protein domain F-box-like PF12937.2 EGC28657.1 - 0.015 15.0 0.6 0.029 14.0 0.4 1.5 1 0 0 1 1 1 0 F-box-like F-box PF00646.28 EGC28657.1 - 0.015 14.9 1.8 0.025 14.2 0.8 1.8 2 0 0 2 2 2 0 F-box domain HEAT_EZ PF13513.1 EGC28657.1 - 0.15 12.6 0.9 19 5.9 0.0 3.6 3 1 1 4 4 4 0 HEAT-like repeat E1-E2_ATPase PF00122.15 EGC28659.1 - 7.6e-53 178.8 1.2 7.6e-53 178.8 0.8 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC28659.1 - 2.5e-39 134.7 7.5 2.5e-39 134.7 5.2 3.3 3 0 0 3 3 3 2 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC28659.1 - 3.8e-28 99.3 0.0 2.6e-27 96.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC28659.1 - 1.8e-16 59.8 0.0 5.5e-16 58.2 0.0 1.8 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGC28659.1 - 1.8e-14 54.3 0.0 3.5e-14 53.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC28659.1 - 8.3e-14 50.8 0.0 1e-12 47.3 0.0 2.6 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGC28659.1 - 0.0031 17.1 0.0 0.0099 15.4 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase SF3b1 PF08920.5 EGC28660.1 - 1.4e-33 115.9 3.2 3e-33 114.9 2.2 1.5 1 0 0 1 1 1 1 Splicing factor 3B subunit 1 HEAT_2 PF13646.1 EGC28660.1 - 1.5e-17 63.6 0.5 0.00057 20.1 0.0 7.1 5 2 2 7 7 7 5 HEAT repeats HEAT PF02985.17 EGC28660.1 - 1.2e-15 56.1 9.5 0.0092 15.9 0.0 10.3 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EGC28660.1 - 6.7e-12 45.5 0.2 1.3 9.5 0.0 8.4 6 2 3 9 9 9 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC28660.1 - 5e-06 26.8 3.0 2.2 8.7 0.0 5.7 6 0 0 6 6 5 2 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGC28660.1 - 8.8e-06 24.3 0.8 0.0035 15.7 0.0 3.5 2 2 1 3 3 3 1 Adaptin N terminal region CTD PF12815.2 EGC28660.1 - 6.4e-05 23.3 0.6 0.00012 22.4 0.4 1.4 1 0 0 1 1 1 1 Spt5 C-terminal nonapeptide repeat binding Spt4 CLASP_N PF12348.3 EGC28660.1 - 8e-05 22.0 0.4 1.6 8.0 0.0 3.8 3 1 0 3 3 3 2 CLASP N terminal Arm PF00514.18 EGC28660.1 - 9.5e-05 22.0 1.4 2.2 8.2 0.0 5.2 5 0 0 5 5 5 2 Armadillo/beta-catenin-like repeat Cnd3 PF12719.2 EGC28660.1 - 0.00068 18.7 0.1 0.15 10.9 0.0 3.5 3 0 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain DUF2435 PF10363.4 EGC28660.1 - 0.052 13.4 1.3 0.81 9.6 0.1 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF2435) HEAT PF02985.17 EGC28661.1 - 2e-30 102.0 4.5 8.8e-05 22.2 0.0 9.7 10 0 0 10 10 10 6 HEAT repeat HEAT_2 PF13646.1 EGC28661.1 - 1.5e-17 63.6 0.0 1.9e-05 24.8 0.0 5.5 2 2 3 5 5 5 4 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC28661.1 - 1.9e-07 31.3 0.3 9.7e-05 22.6 0.0 4.1 3 1 2 6 6 6 1 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGC28661.1 - 3e-07 30.7 0.0 0.52 10.8 0.0 4.8 4 0 0 4 4 4 2 HEAT-like repeat Adaptin_N PF01602.15 EGC28661.1 - 0.0004 18.8 2.9 0.062 11.6 0.3 3.3 2 1 1 3 3 3 2 Adaptin N terminal region RelB_N PF12910.2 EGC28661.1 - 0.0053 16.0 0.0 0.014 14.7 0.0 1.7 1 0 0 1 1 1 1 Antitoxin of toxin-antitoxin stability system N-terminal CLASP_N PF12348.3 EGC28661.1 - 0.006 15.9 0.2 0.06 12.6 0.0 2.6 3 1 0 3 3 3 1 CLASP N terminal DNA_alkylation PF08713.6 EGC28661.1 - 0.013 14.9 0.0 0.48 9.8 0.0 3.3 1 1 2 3 3 3 0 DNA alkylation repair enzyme Cnd1 PF12717.2 EGC28661.1 - 0.042 13.6 2.3 0.26 11.1 0.3 3.0 2 1 1 3 3 3 0 non-SMC mitotic condensation complex subunit 1 CoA_trans PF01144.18 EGC28663.1 - 4.1e-119 395.5 0.5 1.2e-76 256.7 0.1 2.0 2 0 0 2 2 2 2 Coenzyme A transferase DUF1386 PF07138.6 EGC28664.1 - 0.028 13.5 0.2 0.05 12.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1386) Cyclin PF08613.6 EGC28666.1 - 4.3e-34 118.0 0.4 4.3e-34 118.0 0.3 2.2 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGC28666.1 - 2.5e-08 33.5 0.0 6.2e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF2362 PF10154.4 EGC28666.1 - 0.1 11.2 25.0 0.19 10.3 17.3 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) GATase_4 PF13230.1 EGC28667.1 - 7.6e-16 57.5 0.0 3.5e-15 55.4 0.0 1.9 2 1 0 2 2 2 1 Glutamine amidotransferases class-II GATase_6 PF13522.1 EGC28667.1 - 3e-12 46.6 0.0 4.9e-12 45.9 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGC28667.1 - 1.9e-06 26.8 0.0 4.6e-06 25.5 0.0 1.6 2 0 0 2 2 2 1 Glutamine amidotransferases class-II DJ-1_PfpI PF01965.19 EGC28669.1 - 5.2e-27 94.1 0.0 6.4e-27 93.8 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGC28669.1 - 4.3e-18 65.1 0.0 5.1e-18 64.9 0.0 1.0 1 0 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 EGC28669.1 - 0.0008 18.9 0.1 0.00092 18.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I GATase_5 PF13507.1 EGC28669.1 - 0.011 14.7 0.1 0.013 14.4 0.1 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 EGC28669.1 - 0.077 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Pkinase PF00069.20 EGC28670.1 - 5.1e-54 183.1 0.0 5.1e-54 183.1 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28670.1 - 5.5e-17 61.6 0.0 1e-16 60.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28670.1 - 0.015 14.3 0.0 0.032 13.1 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGC28670.1 - 0.035 13.8 0.0 0.12 12.1 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family APC_CDC26 PF10471.4 EGC28670.1 - 1.8 9.3 11.2 4.5 8.0 7.8 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DIE2_ALG10 PF04922.7 EGC28671.1 - 1e-45 156.4 31.0 5e-28 98.2 13.8 2.4 1 1 2 3 3 3 2 DIE2/ALG10 family FimP PF09766.4 EGC28671.1 - 0.0003 19.9 5.9 0.0003 19.9 4.1 1.6 2 0 0 2 2 2 1 Fms-interacting protein Pex14_N PF04695.8 EGC28671.1 - 0.00047 20.2 3.0 0.00072 19.6 2.1 1.3 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region OATP PF03137.15 EGC28671.1 - 0.014 13.4 0.5 0.022 12.8 0.4 1.2 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.8 EGC28671.1 - 0.022 14.7 0.3 0.058 13.3 0.2 1.8 1 0 0 1 1 1 0 Peroxin 13, N-terminal region Ctr PF04145.10 EGC28671.1 - 0.026 14.5 0.0 0.062 13.3 0.0 1.6 1 0 0 1 1 1 0 Ctr copper transporter family Bap31 PF05529.7 EGC28671.1 - 0.13 11.7 0.1 0.13 11.7 0.1 2.2 2 1 0 2 2 2 0 B-cell receptor-associated protein 31-like NRDE-2 PF08424.5 EGC28671.1 - 0.24 10.2 8.8 0.36 9.6 6.1 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Spore_YhcN_YlaJ PF09580.5 EGC28671.1 - 0.3 11.1 17.6 0.48 10.5 12.2 1.3 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) RP-C_C PF11800.3 EGC28671.1 - 0.65 9.6 2.4 0.99 9.0 1.7 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Gti1_Pac2 PF09729.4 EGC28671.1 - 5 6.9 7.2 5.7 6.7 5.0 1.3 1 1 0 1 1 1 0 Gti1/Pac2 family DUF3300 PF11737.3 EGC28671.1 - 5.5 6.1 8.4 11 5.1 5.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) SMP_2 PF10144.4 EGC28672.1 - 0.1 11.7 0.1 0.24 10.5 0.1 1.6 1 0 0 1 1 1 0 Bacterial virulence factor haemolysin GST_C PF00043.20 EGC28673.1 - 9e-08 32.0 0.2 1.6e-07 31.1 0.1 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC28673.1 - 0.024 14.5 0.1 0.043 13.6 0.1 1.4 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC28673.1 - 0.14 12.6 0.0 0.25 11.8 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGC28674.1 - 1.8e-11 44.0 0.0 2.9e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC28674.1 - 4.8e-10 39.2 0.0 8.4e-10 38.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC28674.1 - 3.8e-07 30.2 0.0 5.8e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC28674.1 - 2.9e-06 27.0 0.0 5.1e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC28674.1 - 0.001 19.5 0.0 0.0015 19.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC28674.1 - 0.087 12.8 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain QRPTase_C PF01729.14 EGC28675.1 - 2.4e-58 196.3 0.3 3e-58 196.0 0.2 1.1 1 0 0 1 1 1 1 Quinolinate phosphoribosyl transferase, C-terminal domain QRPTase_N PF02749.11 EGC28675.1 - 5.5e-19 67.7 0.0 1.8e-18 66.1 0.0 1.9 2 1 1 3 3 3 1 Quinolinate phosphoribosyl transferase, N-terminal domain Ribul_P_3_epim PF00834.14 EGC28675.1 - 0.0027 16.8 0.3 0.092 11.8 0.0 2.3 1 1 1 2 2 2 1 Ribulose-phosphate 3 epimerase family IMPDH PF00478.20 EGC28675.1 - 0.064 12.1 0.2 0.089 11.6 0.1 1.1 1 0 0 1 1 1 0 IMP dehydrogenase / GMP reductase domain DUF556 PF04476.8 EGC28675.1 - 0.1 11.8 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF556) DAGK_cat PF00781.19 EGC28677.1 - 2.4e-23 81.9 0.1 5.6e-23 80.8 0.1 1.6 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain NAD_kinase PF01513.16 EGC28677.1 - 2.1e-05 23.4 0.0 4e-05 22.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase DUF3456 PF11938.3 EGC28677.1 - 3.9 7.4 8.7 0.12 12.3 0.2 2.5 3 0 0 3 3 3 0 TLR4 regulator and MIR-interacting MSAP Folate_carrier PF01770.13 EGC28680.1 - 2.1e-52 178.0 50.8 1.2e-26 93.2 7.4 4.9 2 2 3 5 5 5 3 Reduced folate carrier MFS_1 PF07690.11 EGC28680.1 - 0.0081 14.9 30.4 0.55 8.8 20.3 3.1 1 1 0 1 1 1 1 Major Facilitator Superfamily CBS PF00571.23 EGC28681.1 - 6.5e-33 112.2 2.2 1.4e-12 47.2 0.0 4.4 4 0 0 4 4 4 4 CBS domain Costars PF14705.1 EGC28682.1 - 2.4e-30 104.3 1.2 2.7e-30 104.1 0.8 1.0 1 0 0 1 1 1 1 Costars TSC22 PF01166.13 EGC28682.1 - 0.099 12.6 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Costars PF14705.1 EGC28683.1 - 2.4e-30 104.3 1.2 2.7e-30 104.1 0.8 1.0 1 0 0 1 1 1 1 Costars TSC22 PF01166.13 EGC28683.1 - 0.099 12.6 0.1 0.18 11.8 0.0 1.4 1 0 0 1 1 1 0 TSC-22/dip/bun family Pribosyltran_N PF13793.1 EGC28684.1 - 9.4e-44 147.8 0.5 1.5e-42 143.9 0.0 2.2 2 0 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGC28684.1 - 5.7e-34 117.4 3.8 5.3e-32 111.0 2.1 2.4 2 0 0 2 2 2 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGC28684.1 - 1e-10 41.3 0.6 4.1e-10 39.4 0.4 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AF2331-like PF14556.1 EGC28684.1 - 0.094 13.0 3.3 2.7 8.4 0.0 2.7 3 0 0 3 3 3 0 AF2331-like HD PF01966.17 EGC28685.1 - 1e-15 57.7 0.5 2.8e-15 56.3 0.4 1.8 1 0 0 1 1 1 1 HD domain Ras PF00071.17 EGC28686.1 - 2.8e-45 153.5 0.0 3.3e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28686.1 - 4.8e-18 65.7 0.0 6.4e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC28686.1 - 5.5e-13 48.5 0.0 7e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC28686.1 - 0.00054 19.1 0.0 0.00068 18.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC28686.1 - 0.0026 17.7 0.0 0.0035 17.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC28686.1 - 0.028 13.8 0.0 0.063 12.7 0.0 1.4 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain GRAM PF02893.15 EGC28687.1 - 1.3e-09 37.4 0.1 3.3e-09 36.1 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Adeno_E3 PF06040.6 EGC28687.1 - 0.067 13.1 0.2 0.067 13.1 0.2 2.6 2 0 0 2 2 2 0 Adenovirus E3 protein adh_short PF00106.20 EGC28688.1 - 1.8e-19 70.2 0.0 2.4e-19 69.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC28688.1 - 3.5e-18 66.2 0.0 5.3e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC28688.1 - 3.5e-07 30.0 0.0 4.8e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC28688.1 - 6.7e-06 25.7 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC28688.1 - 2.7e-05 22.9 0.3 4.2e-05 22.3 0.2 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF1776 PF08643.5 EGC28688.1 - 0.00028 20.1 0.0 0.00036 19.7 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC28688.1 - 0.0042 17.1 0.0 0.0087 16.0 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC28688.1 - 0.0071 15.2 0.0 0.01 14.7 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC28688.1 - 0.025 13.4 0.0 0.037 12.9 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Saccharop_dh PF03435.13 EGC28688.1 - 0.11 11.4 0.1 0.38 9.6 0.0 1.8 2 0 0 2 2 2 0 Saccharopine dehydrogenase DUF953 PF06110.6 EGC28689.1 - 1.6e-09 37.2 0.4 1.9e-09 37.0 0.2 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF953) Thioredoxin PF00085.15 EGC28689.1 - 0.0089 15.6 0.6 0.017 14.7 0.4 1.5 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EGC28689.1 - 0.1 12.1 0.2 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Thioredoxin Gelsolin PF00626.17 EGC28690.1 - 2.5e-48 161.6 3.9 8.3e-13 47.8 0.0 5.9 5 0 0 5 5 5 5 Gelsolin repeat PBD PF00786.23 EGC28690.1 - 7.1e-19 67.9 0.2 7e-09 35.9 0.1 4.0 2 0 0 2 2 2 2 P21-Rho-binding domain eIF_4EBP PF05456.6 EGC28691.1 - 2e-27 95.1 3.4 2.2e-27 95.0 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) DSPc PF00782.15 EGC28692.1 - 6.9e-09 35.3 0.0 9.2e-09 34.9 0.0 1.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC28692.1 - 1.9e-07 30.6 0.0 2.1e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase CDKN3 PF05706.7 EGC28692.1 - 1.3e-06 27.9 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) MOZART1 PF12554.3 EGC28692.1 - 0.069 12.6 0.1 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 Mitotic-spindle organizing gamma-tubulin ring associated Cut8_C PF08559.5 EGC28693.1 - 1.2e-12 47.8 0.3 2.3e-12 46.9 0.2 1.6 1 1 0 1 1 1 1 Cut8 six-helix bundle Nnf1 PF03980.9 EGC28693.1 - 0.018 15.0 2.8 4.8 7.2 0.0 3.0 3 0 0 3 3 3 0 Nnf1 Snf7 PF03357.16 EGC28693.1 - 0.28 10.5 7.1 8.8 5.6 0.0 2.5 2 0 0 2 2 2 0 Snf7 DUF2804 PF10974.3 EGC28694.1 - 2.4e-100 335.6 1.2 2.9e-100 335.3 0.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) Lipoprotein_3 PF00938.12 EGC28694.1 - 0.055 13.2 0.0 0.23 11.2 0.0 2.0 1 0 0 1 1 1 0 Lipoprotein Myb_DNA-binding PF00249.26 EGC28696.1 - 1.2e-09 38.1 0.3 2e-09 37.3 0.2 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Thioredoxin_6 PF13848.1 EGC28697.1 - 0.066 13.0 0.1 0.074 12.8 0.1 1.2 1 0 0 1 1 1 0 Thioredoxin-like domain SLX9 PF15341.1 EGC28698.1 - 8.7e-19 68.1 14.3 8.7e-19 68.1 9.9 2.4 3 0 0 3 3 3 1 Ribosome biogenesis protein SLX9 Aminotran_1_2 PF00155.16 EGC28699.1 - 6.3e-84 281.9 0.0 7.3e-84 281.7 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II SKG6 PF08693.5 EGC28700.1 - 0.0037 16.5 0.6 0.0037 16.5 0.4 2.1 2 0 0 2 2 2 1 Transmembrane alpha-helix domain DUF4448 PF14610.1 EGC28700.1 - 0.024 14.1 0.5 0.043 13.3 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1883 PF08980.5 EGC28700.1 - 2.5 7.7 5.2 1.8 8.1 2.3 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF1883) PhyH PF05721.8 EGC28701.1 - 5.2e-23 82.1 0.0 6.4e-23 81.8 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) HMG_box PF00505.14 EGC28702.1 - 1.1e-19 70.4 2.2 2.2e-19 69.4 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGC28702.1 - 5.8e-16 58.6 3.6 1.2e-15 57.5 2.5 1.6 1 0 0 1 1 1 1 HMG-box domain CHDNT PF08073.7 EGC28702.1 - 0.068 12.8 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 CHDNT (NUC034) domain 4HBT_2 PF13279.1 EGC28703.1 - 8e-05 23.0 0.0 0.00011 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Tubulin PF00091.20 EGC28704.1 - 8.8e-32 110.6 3.5 3.8e-31 108.5 2.4 2.0 1 1 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain FtsZ_C PF12327.3 EGC28704.1 - 2.6e-22 78.6 0.1 9e-22 76.9 0.0 1.9 2 0 0 2 2 2 1 FtsZ family, C-terminal domain Peptidase_M24 PF00557.19 EGC28705.1 - 4.4e-39 134.2 0.0 5.6e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 NST1 PF13945.1 EGC28705.1 - 0.028 14.4 0.9 0.045 13.8 0.7 1.3 1 0 0 1 1 1 0 Salt tolerance down-regulator Inhibitor_I53 PF11714.3 EGC28705.1 - 0.97 9.4 4.7 0.73 9.8 2.0 1.7 2 0 0 2 2 2 0 Thrombin inhibitor Madanin zf-DBF PF07535.7 EGC28707.1 - 1.4e-17 63.0 1.7 5.4e-17 61.2 1.2 2.1 1 0 0 1 1 1 1 DBF zinc finger DUF885 PF05960.6 EGC28708.1 - 1.5e-78 265.3 0.0 1.9e-78 265.0 0.0 1.1 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) YesK PF14150.1 EGC28709.1 - 0.097 12.7 0.3 0.097 12.7 0.2 4.9 6 0 0 6 6 6 0 YesK-like protein Clavanin PF05452.6 EGC28709.1 - 0.21 11.5 1.9 0.7 9.9 1.3 2.0 1 0 0 1 1 1 0 Clavanin DUF4337 PF14235.1 EGC28711.1 - 0.038 13.8 2.4 0.046 13.5 1.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF4634 PF15465.1 EGC28712.1 - 0.28 11.3 3.7 0.96 9.6 2.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4634) STN PF07660.9 EGC28715.1 - 0.11 12.0 0.0 0.13 11.8 0.0 1.1 1 0 0 1 1 1 0 Secretin and TonB N terminus short domain BTB PF00651.26 EGC28716.1 - 3.9e-21 75.1 5.3 3.5e-19 68.8 0.9 3.2 2 1 1 3 3 3 2 BTB/POZ domain BACK PF07707.10 EGC28716.1 - 1.2e-11 44.3 2.3 3.1e-09 36.5 0.1 3.2 2 1 0 3 3 3 2 BTB And C-terminal Kelch NOA36 PF06524.7 EGC28716.1 - 2.3 7.3 10.5 0.58 9.3 4.8 1.7 2 0 0 2 2 2 0 NOA36 protein MFS_1 PF07690.11 EGC28717.1 - 1.9e-08 33.4 43.7 1.4e-07 30.6 12.1 3.0 1 1 1 3 3 3 2 Major Facilitator Superfamily DUF3139 PF11337.3 EGC28718.1 - 0.007 16.6 0.2 0.0082 16.3 0.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3139) Neur_chan_memb PF02932.11 EGC28718.1 - 0.033 14.0 0.2 0.037 13.9 0.1 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nop25 PF09805.4 EGC28718.1 - 0.049 13.6 3.9 0.058 13.4 2.7 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) Tetraspannin PF00335.15 EGC28718.1 - 0.11 11.8 1.2 0.13 11.4 0.9 1.1 1 0 0 1 1 1 0 Tetraspanin family P5-ATPase PF12409.3 EGC28718.1 - 4.4 7.1 7.1 4.4 7.1 4.8 1.3 1 1 0 1 1 1 0 P5-type ATPase cation transporter Formyl_trans_N PF00551.14 EGC28719.1 - 7.7e-20 71.1 0.0 1.2e-19 70.5 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EGC28719.1 - 0.012 15.6 0.1 6.8 6.8 0.0 2.4 2 0 0 2 2 2 0 Formyl transferase, C-terminal domain GYR PF02756.9 EGC28719.1 - 0.25 11.1 2.0 0.64 9.8 1.4 1.7 1 0 0 1 1 1 0 GYR motif PA14 PF07691.7 EGC28721.1 - 1.9e-06 27.6 0.0 4.7e-06 26.3 0.0 1.7 1 0 0 1 1 1 1 PA14 domain Ras PF00071.17 EGC28722.1 - 2.7e-31 108.1 4.3 1.6e-20 73.1 0.0 3.2 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EGC28722.1 - 2e-28 99.2 0.1 2.7e-13 50.4 0.0 2.5 2 0 0 2 2 2 2 Miro-like protein EF_assoc_1 PF08355.7 EGC28722.1 - 9.6e-19 66.4 0.1 1.8e-18 65.5 0.0 1.5 1 0 0 1 1 1 1 EF hand associated EF_assoc_2 PF08356.7 EGC28722.1 - 1e-15 57.2 0.4 9e-13 47.8 0.1 3.5 2 1 0 2 2 2 1 EF hand associated MMR_HSR1 PF01926.18 EGC28722.1 - 1.7e-09 37.6 2.4 1.7e-05 24.7 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase EF-hand_1 PF00036.27 EGC28722.1 - 8.5e-09 34.0 0.6 0.003 16.7 0.0 3.4 3 0 0 3 3 2 2 EF hand GTP_EFTU PF00009.22 EGC28722.1 - 9.8e-09 34.9 0.1 0.00028 20.3 0.0 3.9 3 1 0 4 4 4 1 Elongation factor Tu GTP binding domain EF-hand_6 PF13405.1 EGC28722.1 - 3.2e-08 32.8 0.5 0.0023 17.6 0.0 3.4 3 0 0 3 3 2 2 EF-hand domain EF-hand_7 PF13499.1 EGC28722.1 - 1.5e-07 31.4 2.5 2e-06 27.8 0.5 3.2 2 1 0 2 2 2 1 EF-hand domain pair Septin PF00735.13 EGC28722.1 - 1e-05 24.7 0.3 0.039 12.9 0.0 3.0 3 0 0 3 3 3 2 Septin EF-hand_5 PF13202.1 EGC28722.1 - 1.5e-05 24.1 1.3 0.092 12.1 0.0 3.1 3 0 0 3 3 3 2 EF hand Arch_ATPase PF01637.13 EGC28722.1 - 2.1e-05 24.3 0.4 0.24 11.0 0.0 2.8 2 0 0 2 2 2 2 Archaeal ATPase Arf PF00025.16 EGC28722.1 - 6e-05 22.3 0.0 0.0067 15.6 0.1 2.9 2 1 0 2 2 2 1 ADP-ribosylation factor family Dynamin_N PF00350.18 EGC28722.1 - 0.00013 21.7 0.2 1.4 8.6 0.0 3.3 3 0 0 3 3 3 2 Dynamin family AAA_22 PF13401.1 EGC28722.1 - 0.00049 20.2 0.4 3.3 7.8 0.0 4.1 4 2 0 4 4 3 1 AAA domain FeoB_N PF02421.13 EGC28722.1 - 0.00056 19.2 0.5 0.059 12.6 0.0 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B RNA_helicase PF00910.17 EGC28722.1 - 0.00095 19.3 0.5 5.1 7.3 0.0 3.6 3 1 0 3 3 3 1 RNA helicase AAA_24 PF13479.1 EGC28722.1 - 0.001 18.6 0.0 1 8.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGC28722.1 - 0.0019 18.1 0.6 5.2 6.9 0.0 3.5 3 0 0 3 3 3 1 AAA domain EF-hand_8 PF13833.1 EGC28722.1 - 0.0019 17.7 0.6 1.6 8.3 0.0 3.4 3 0 0 3 3 3 1 EF-hand domain pair DUF258 PF03193.11 EGC28722.1 - 0.003 16.7 0.0 0.32 10.1 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EGC28722.1 - 0.0056 16.3 0.3 0.29 10.8 0.0 2.8 2 1 1 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B EF-hand_10 PF14788.1 EGC28722.1 - 0.013 15.1 0.3 0.013 15.1 0.2 2.7 3 0 0 3 3 2 0 EF hand AAA PF00004.24 EGC28722.1 - 0.017 15.3 0.1 6.7 6.9 0.0 2.8 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC28722.1 - 0.027 14.4 0.0 9.8 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain AAA_29 PF13555.1 EGC28722.1 - 0.033 13.6 0.0 11 5.6 0.0 3.2 3 0 0 3 3 3 0 P-loop containing region of AAA domain SPARC_Ca_bdg PF10591.4 EGC28722.1 - 0.042 13.8 0.2 0.58 10.2 0.1 2.7 2 0 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region FtsK_SpoIIIE PF01580.13 EGC28722.1 - 0.13 11.6 0.0 2.5 7.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF367 PF04034.8 EGC28723.1 - 1.4e-51 173.3 0.0 1.7e-51 173.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF367) RLI PF04068.10 EGC28723.1 - 1.5e-11 43.6 0.0 3.9e-11 42.3 0.0 1.8 1 0 0 1 1 1 1 Possible Fer4-like domain in RNase L inhibitor, RLI DUF2034 PF10356.4 EGC28724.1 - 2.3e-09 36.6 0.2 1.8e-05 23.9 0.0 3.6 2 2 3 5 5 5 2 Protein of unknown function (DUF2034) Daxx PF03344.10 EGC28724.1 - 6.4e-05 21.6 53.2 9.2e-05 21.1 36.9 1.3 1 0 0 1 1 1 1 Daxx Family FAD_binding_1 PF00667.15 EGC28725.1 - 7e-41 140.0 0.5 1.5e-40 139.0 0.4 1.4 1 0 0 1 1 1 1 FAD binding domain NAD_binding_1 PF00175.16 EGC28725.1 - 7.4e-18 65.1 0.0 1.3e-17 64.3 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGC28725.1 - 0.03 14.2 0.5 0.2 11.5 0.2 2.5 2 1 0 2 2 2 0 Ferric reductase NAD binding domain Peptidase_S24 PF00717.18 EGC28725.1 - 0.089 12.4 0.3 0.29 10.7 0.1 1.9 1 1 1 2 2 2 0 Peptidase S24-like Vps52 PF04129.7 EGC28728.1 - 2e-05 23.3 0.0 2.4e-05 23.0 0.0 1.0 1 0 0 1 1 1 1 Vps52 / Sac2 family PIP5K PF01504.13 EGC28729.1 - 1.5e-61 207.7 5.4 1.5e-61 207.7 3.8 2.2 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase LAGLIDADG_WhiA PF14527.1 EGC28729.1 - 0.11 12.3 2.4 0.28 11.0 1.7 1.7 1 0 0 1 1 1 0 WhiA LAGLIDADG-like domain RhoGEF PF00621.15 EGC28731.1 - 1.1e-40 139.3 3.5 1.1e-40 139.3 2.4 2.9 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 EGC28731.1 - 0.0012 19.0 0.5 0.0012 19.0 0.4 2.3 2 0 0 2 2 2 1 PH domain SNF2_N PF00176.18 EGC28734.1 - 1.4e-64 217.7 0.8 2.3e-64 217.0 0.5 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC28734.1 - 3.4e-13 49.2 0.3 1.5e-12 47.1 0.0 2.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGC28734.1 - 1.3e-06 27.9 5.3 2.5e-06 27.0 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC28734.1 - 1.1e-05 25.2 9.0 2.6e-05 24.0 6.2 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGC28734.1 - 2e-05 24.5 8.6 5.1e-05 23.2 5.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28734.1 - 3.1e-05 23.5 8.9 6.9e-05 22.4 6.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC28734.1 - 0.0032 17.2 7.1 0.0075 16.0 4.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC28734.1 - 0.016 14.9 8.6 0.035 13.8 6.0 1.6 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_6 PF14835.1 EGC28734.1 - 0.078 12.7 2.5 0.18 11.6 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC28734.1 - 0.086 12.5 5.4 0.31 10.8 3.7 2.0 1 0 0 1 1 1 0 RING-type zinc-finger SMN PF06003.7 EGC28735.1 - 1.9e-07 30.5 25.3 0.025 13.6 17.5 2.6 1 1 0 1 1 1 1 Survival motor neuron protein (SMN) SID-1_RNA_chan PF13965.1 EGC28735.1 - 1.4 6.9 8.5 2.2 6.3 5.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Ribosomal_S13 PF00416.17 EGC28736.1 - 2.8e-35 120.9 2.1 3.4e-35 120.7 1.4 1.1 1 0 0 1 1 1 1 Ribosomal protein S13/S18 FbpA PF05833.6 EGC28736.1 - 0.015 13.9 0.0 0.015 13.8 0.0 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) HHH_6 PF14579.1 EGC28736.1 - 0.062 13.3 0.1 0.2 11.7 0.0 1.8 2 1 0 2 2 2 0 Helix-hairpin-helix motif Transketolase_C PF02780.15 EGC28737.1 - 2.8e-44 149.9 0.6 6.3e-44 148.8 0.3 1.7 2 0 0 2 2 2 1 Transketolase, C-terminal domain Transket_pyr PF02779.19 EGC28737.1 - 1.7e-43 148.1 0.0 2.5e-43 147.6 0.0 1.3 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Amdo_NSP PF12475.3 EGC28738.1 - 1.9 8.4 11.6 0.46 10.4 0.1 3.5 3 0 0 3 3 3 0 Amdovirus non-structural protein Pkinase PF00069.20 EGC28739.1 - 1.1e-67 227.9 0.3 4.7e-45 153.7 0.1 3.2 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28739.1 - 1.7e-28 99.3 0.0 8.5e-21 74.1 0.0 2.8 3 0 0 3 3 3 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC28739.1 - 0.0002 20.4 0.0 0.0005 19.1 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Pkinase_C PF00433.19 EGC28739.1 - 0.00025 21.4 3.6 0.00025 21.4 2.5 3.0 3 0 0 3 3 3 1 Protein kinase C terminal domain APH PF01636.18 EGC28739.1 - 0.002 17.9 0.1 0.0044 16.7 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC28739.1 - 0.04 12.9 0.0 0.073 12.1 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Leu_zip PF15294.1 EGC28740.1 - 0.0069 15.5 35.8 0.011 14.8 24.8 1.3 1 0 0 1 1 1 1 Leucine zipper DUF3972 PF13118.1 EGC28740.1 - 0.017 15.2 1.0 0.017 15.2 0.7 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3972) Filament PF00038.16 EGC28740.1 - 0.14 11.6 32.3 0.68 9.3 22.4 1.9 1 1 0 1 1 1 0 Intermediate filament protein DUF869 PF05911.6 EGC28740.1 - 0.25 9.5 31.2 0.32 9.1 21.6 1.0 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) AIP3 PF03915.8 EGC28740.1 - 0.52 9.1 29.1 1.6 7.5 5.1 2.1 1 1 1 2 2 2 0 Actin interacting protein 3 ADIP PF11559.3 EGC28740.1 - 0.52 10.1 40.6 0.22 11.4 16.5 2.3 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TPR_MLP1_2 PF07926.7 EGC28740.1 - 0.56 9.9 44.6 0.75 9.5 7.8 3.0 1 1 2 3 3 3 0 TPR/MLP1/MLP2-like protein DUF4200 PF13863.1 EGC28740.1 - 0.61 10.0 43.5 3.2 7.7 4.0 3.1 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) DUF4559 PF15112.1 EGC28740.1 - 0.69 9.0 23.6 1.1 8.3 16.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Atg14 PF10186.4 EGC28740.1 - 0.88 8.4 36.4 0.41 9.5 12.6 2.1 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Retrotrans_gag PF03732.12 EGC28740.1 - 1.3 9.1 14.1 0.39 10.8 6.8 2.3 1 1 1 2 2 2 0 Retrotransposon gag protein DUF1640 PF07798.6 EGC28740.1 - 1.4 8.9 27.7 8.5 6.3 19.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) FTA4 PF13093.1 EGC28740.1 - 1.4 8.2 30.0 2.2 7.6 20.8 1.2 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 MCPsignal PF00015.16 EGC28740.1 - 2 7.9 8.4 0.67 9.4 4.0 1.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WEMBL PF05701.6 EGC28740.1 - 3 6.1 32.3 0.15 10.4 17.9 1.7 1 1 0 2 2 2 0 Weak chloroplast movement under blue light DUF883 PF05957.8 EGC28740.1 - 4.1 7.8 16.0 1.2 9.6 2.2 3.1 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF883) LMBR1 PF04791.11 EGC28740.1 - 4.1 5.8 12.3 6.3 5.2 8.5 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Mnd1 PF03962.10 EGC28740.1 - 4.6 6.8 35.7 5.9 6.5 11.8 2.3 1 1 1 2 2 2 0 Mnd1 family BLOC1_2 PF10046.4 EGC28740.1 - 4.8 7.3 31.9 1.2 9.3 6.6 3.6 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HlyD PF00529.15 EGC28740.1 - 6.2 6.0 15.7 8.6 5.5 10.9 1.2 1 0 0 1 1 1 0 HlyD family secretion protein DUF3584 PF12128.3 EGC28740.1 - 6.9 3.8 37.8 19 2.3 26.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) DUF972 PF06156.8 EGC28740.1 - 8.1 6.8 36.1 2.7 8.3 6.3 3.1 1 1 1 2 2 1 0 Protein of unknown function (DUF972) Ax_dynein_light PF10211.4 EGC28740.1 - 8.6 6.1 39.7 1.6 8.5 8.9 2.7 1 1 1 2 2 2 0 Axonemal dynein light chain EMG1 PF03587.9 EGC28741.1 - 1.6e-93 311.6 1.2 3.9e-93 310.3 0.8 1.6 1 1 0 1 1 1 1 EMG1/NEP1 methyltransferase DDHD PF02862.12 EGC28741.1 - 3.2e-05 23.8 0.4 4.9e-05 23.2 0.3 1.4 1 0 0 1 1 1 1 DDHD domain Sporozoite_P67 PF05642.6 EGC28741.1 - 0.008 14.1 7.9 0.011 13.6 5.5 1.1 1 0 0 1 1 1 1 Sporozoite P67 surface antigen TRAP_alpha PF03896.11 EGC28741.1 - 0.023 13.7 2.4 0.032 13.2 1.7 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Tim54 PF11711.3 EGC28741.1 - 0.027 13.0 1.9 0.035 12.7 1.3 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 GAGA_bind PF06217.7 EGC28741.1 - 0.028 14.4 4.1 0.04 13.8 2.8 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF1510 PF07423.6 EGC28741.1 - 0.03 13.7 11.2 0.039 13.3 7.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGC28741.1 - 0.08 10.9 6.1 0.11 10.5 4.2 1.1 1 0 0 1 1 1 0 CDC45-like protein Dicty_REP PF05086.7 EGC28741.1 - 0.14 9.8 10.1 0.21 9.2 7.0 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Vfa1 PF08432.5 EGC28741.1 - 0.24 11.4 12.9 0.37 10.8 8.9 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Nop14 PF04147.7 EGC28741.1 - 0.69 7.7 13.8 0.98 7.2 9.6 1.1 1 0 0 1 1 1 0 Nop14-like family POX PF07526.6 EGC28741.1 - 0.72 10.0 6.1 1.2 9.3 4.2 1.3 1 0 0 1 1 1 0 Associated with HOX Hid1 PF12722.2 EGC28741.1 - 0.76 7.3 5.8 1 6.9 4.0 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein NPR3 PF03666.8 EGC28741.1 - 0.79 8.1 6.6 0.2 10.1 2.7 1.4 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 YqfQ PF14181.1 EGC28741.1 - 0.83 9.6 13.4 1.5 8.8 9.3 1.4 1 0 0 1 1 1 0 YqfQ-like protein DUF912 PF06024.7 EGC28741.1 - 3.2 7.8 5.4 6.3 6.9 3.7 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RRN3 PF05327.6 EGC28741.1 - 4.2 5.3 6.7 5.7 4.9 4.6 1.1 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF2201_N PF13203.1 EGC28741.1 - 5.5 6.0 6.8 7.6 5.6 4.7 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain MDFI PF15316.1 EGC28741.1 - 6.1 6.8 6.2 11 6.0 4.3 1.3 1 0 0 1 1 1 0 MyoD family inhibitor Viral_env_E26 PF11050.3 EGC28742.1 - 0.037 13.2 1.9 0.038 13.1 1.3 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 Scm3 PF10384.4 EGC28742.1 - 0.047 13.1 1.4 0.07 12.6 0.6 1.6 1 1 0 1 1 1 0 Centromere protein Scm3 Atg14 PF10186.4 EGC28742.1 - 0.072 12.0 4.6 0.072 12.0 3.2 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 LAGLIDADG_1 PF00961.14 EGC28742.1 - 0.074 13.6 5.3 0.082 13.4 3.7 1.1 1 0 0 1 1 1 0 LAGLIDADG endonuclease FNIP_M PF14637.1 EGC28742.1 - 0.18 11.3 4.4 0.19 11.2 3.1 1.0 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain HAUS-augmin3 PF14932.1 EGC28742.1 - 0.36 9.9 8.8 0.41 9.7 6.1 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 3 ACCA PF03255.9 EGC28742.1 - 0.39 10.2 4.3 0.42 10.1 3.0 1.2 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DUF4168 PF13767.1 EGC28742.1 - 0.56 10.8 5.1 0.71 10.5 3.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4168) 60KD_IMP PF02096.15 EGC28742.1 - 0.65 9.6 3.3 0.69 9.5 2.3 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein DUF2935 PF11155.3 EGC28742.1 - 0.82 9.7 6.3 0.94 9.5 4.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF2935) DUF342 PF03961.8 EGC28742.1 - 9.7 4.4 10.7 9.8 4.4 7.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) PPP4R2 PF09184.6 EGC28743.1 - 1.3e-21 77.4 11.6 2.3e-21 76.6 8.0 1.5 1 1 0 1 1 1 1 PPP4R2 Tup_N PF08581.5 EGC28743.1 - 0.12 12.5 1.1 0.25 11.5 0.1 2.0 2 0 0 2 2 2 0 Tup N-terminal AA_permease_N PF08403.5 EGC28747.1 - 0.035 13.4 0.1 0.071 12.4 0.1 1.4 1 0 0 1 1 1 0 Amino acid permease N-terminal DUF4419 PF14388.1 EGC28748.1 - 5.7e-105 350.7 1.5 6.7e-105 350.5 1.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Acetyltransf_2 PF00797.12 EGC28749.1 - 1.9e-29 102.9 1.1 9.2e-29 100.6 0.8 1.8 1 1 0 1 1 1 1 N-acetyltransferase Ribonucleas_3_3 PF14622.1 EGC28750.1 - 0.00015 21.6 0.6 0.00072 19.5 0.0 2.0 2 0 0 2 2 2 1 Ribonuclease-III-like DUF525 PF04379.9 EGC28751.1 - 1e-13 51.0 0.0 1.6e-13 50.4 0.0 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF525) Peptidase_M16_C PF05193.16 EGC28753.1 - 1.3e-26 93.4 0.1 4.7e-26 91.6 0.0 2.0 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC28753.1 - 6.4e-24 84.4 0.0 1.4e-23 83.3 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Death PF00531.17 EGC28753.1 - 0.024 14.3 0.9 22 4.8 0.0 3.9 4 0 0 4 4 4 0 Death domain Beta-lactamase PF00144.19 EGC28754.1 - 5.9e-42 143.8 0.0 9.4e-42 143.1 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase Peptidase_M15 PF01427.12 EGC28754.1 - 4.4e-25 88.4 0.0 1.2e-24 87.0 0.0 1.8 1 1 0 1 1 1 1 D-ala-D-ala dipeptidase Extensin-like_C PF06904.7 EGC28754.1 - 0.042 13.6 0.0 0.085 12.6 0.0 1.4 1 0 0 1 1 1 0 Extensin-like protein C-terminus DUF3437 PF11919.3 EGC28755.1 - 0.035 13.8 0.2 0.056 13.1 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3437) p450 PF00067.17 EGC28757.1 - 1.1e-97 327.5 0.2 1.2e-97 327.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 CW_binding_2 PF04122.7 EGC28758.1 - 0.37 11.0 2.9 0.61 10.3 0.4 1.8 1 1 1 2 2 2 0 Putative cell wall binding repeat 2 Band_7 PF01145.20 EGC28759.1 - 4.8e-24 85.2 0.2 2.6e-23 82.8 0.0 2.1 2 1 0 2 2 2 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGC28759.1 - 0.01 15.3 0.5 0.02 14.4 0.0 1.7 2 0 0 2 2 2 0 SPFH domain-Band 7 family Imm41 PF15583.1 EGC28759.1 - 0.013 15.3 0.5 0.039 13.7 0.1 1.9 2 0 0 2 2 2 0 Immunity protein 41 LRR_6 PF13516.1 EGC28760.1 - 5.5e-23 78.4 42.5 0.015 15.2 0.0 13.9 13 0 0 13 13 13 7 Leucine Rich repeat LRR_4 PF12799.2 EGC28760.1 - 1.5e-12 46.7 46.5 0.0064 16.1 0.3 9.3 5 2 2 8 8 8 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC28760.1 - 2.1e-07 30.0 30.6 2.8 8.2 0.5 13.0 11 2 1 12 12 12 2 Leucine Rich Repeat DUF531 PF04407.7 EGC28760.1 - 0.063 13.1 0.0 0.28 11.0 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF531) F-box-like PF12937.2 EGC28760.1 - 0.085 12.6 0.0 0.51 10.1 0.0 2.1 1 1 0 1 1 1 0 F-box-like LRR_7 PF13504.1 EGC28760.1 - 0.52 10.7 24.0 27 5.5 0.1 10.0 11 0 0 11 11 11 0 Leucine rich repeat Trypan_PARP PF05887.6 EGC28760.1 - 0.83 9.4 22.5 1.9 8.3 15.6 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) MIP-T3 PF10243.4 EGC28760.1 - 8.4 4.7 69.4 0.89 7.9 45.1 1.5 1 1 0 1 1 1 0 Microtubule-binding protein MIP-T3 Y_phosphatase PF00102.22 EGC28761.1 - 6.1e-75 251.5 3.0 1e-64 218.1 0.8 2.3 2 0 0 2 2 2 2 Protein-tyrosine phosphatase DSPc PF00782.15 EGC28761.1 - 3.2e-08 33.2 0.0 8.2e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGC28761.1 - 0.00054 20.0 0.0 0.0018 18.3 0.0 1.9 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGC28761.1 - 0.0025 18.0 0.1 0.0079 16.4 0.0 1.9 2 0 0 2 2 2 1 Tyrosine phosphatase family ICAP-1_inte_bdg PF10480.4 EGC28761.1 - 0.052 13.3 0.1 0.11 12.3 0.1 1.5 1 0 0 1 1 1 0 Beta-1 integrin binding protein HSBP1 PF06825.7 EGC28762.1 - 1.6e-20 72.4 4.7 2.8e-20 71.6 3.3 1.4 1 0 0 1 1 1 1 Heat shock factor binding protein 1 Hormone_1 PF00103.15 EGC28762.1 - 0.011 15.0 5.9 0.013 14.8 4.1 1.2 1 0 0 1 1 1 0 Somatotropin hormone family HXXSHH PF07586.6 EGC28762.1 - 0.016 14.1 3.4 0.018 14.0 2.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1552) IncA PF04156.9 EGC28762.1 - 0.094 12.3 4.8 0.1 12.2 3.3 1.2 1 0 0 1 1 1 0 IncA protein Peptidase_S49_N PF08496.5 EGC28762.1 - 0.11 12.2 3.7 0.14 11.9 2.6 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1664 PF07889.7 EGC28762.1 - 0.14 11.9 3.1 0.21 11.4 2.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) YvrJ PF12841.2 EGC28762.1 - 0.15 11.3 1.0 3 7.2 0.1 2.3 1 1 1 2 2 2 0 YvrJ protein family DivIVA PF05103.8 EGC28762.1 - 0.87 9.6 10.7 0.99 9.4 7.3 1.3 1 1 0 1 1 1 0 DivIVA protein RP-C_C PF11800.3 EGC28762.1 - 1.3 8.6 8.1 1.7 8.3 5.6 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Serinc PF03348.10 EGC28762.1 - 2 7.0 7.5 2.1 6.9 5.2 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Ndc1_Nup PF09531.5 EGC28762.1 - 2.1 6.6 9.5 2.3 6.5 6.6 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4611 PF15387.1 EGC28762.1 - 2.5 8.3 9.2 2.3 8.4 5.6 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4611) HAUS6_N PF14661.1 EGC28762.1 - 3.6 6.8 10.0 3.7 6.8 6.9 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus Band_3_cyto PF07565.8 EGC28762.1 - 5.4 6.4 7.8 5.9 6.3 5.4 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain DUF4094 PF13334.1 EGC28762.1 - 7.6 6.9 13.5 0.2 12.0 0.4 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) p450 PF00067.17 EGC28763.1 - 6e-58 196.4 0.0 7.5e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 TMEMspv1-c74-12 PF11044.3 EGC28763.1 - 3.9 7.0 5.7 0.67 9.5 1.0 2.0 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein adh_short PF00106.20 EGC28764.1 - 8.6e-29 100.5 0.0 1.1e-28 100.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC28764.1 - 3e-15 56.3 0.0 4.2e-15 55.8 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC28764.1 - 6.1e-09 35.9 0.0 8.2e-09 35.5 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase THF_DHG_CYH_C PF02882.14 EGC28764.1 - 5.6e-06 25.5 0.0 1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Shikimate_DH PF01488.15 EGC28764.1 - 7.5e-05 22.8 0.0 0.00015 21.9 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_10 PF13460.1 EGC28764.1 - 0.0012 18.8 0.0 0.085 12.8 0.0 2.5 1 1 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC28764.1 - 0.0048 16.3 0.0 0.0081 15.6 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC28764.1 - 0.0049 15.7 0.2 0.0078 15.1 0.2 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EGC28764.1 - 0.0065 16.7 0.0 0.014 15.6 0.0 1.6 1 0 0 1 1 1 1 Putative NAD(P)-binding 3Beta_HSD PF01073.14 EGC28764.1 - 0.01 14.5 0.0 0.013 14.2 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family IPPT PF01715.12 EGC28765.1 - 1.2e-42 145.6 4.2 2.8e-41 141.1 2.9 2.0 1 1 0 1 1 1 1 IPP transferase IPT PF01745.11 EGC28765.1 - 1.5e-07 30.8 0.0 3.8e-07 29.5 0.0 1.7 2 0 0 2 2 2 1 Isopentenyl transferase Zeta_toxin PF06414.7 EGC28765.1 - 6.7e-05 22.0 0.2 0.00023 20.3 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_17 PF13207.1 EGC28765.1 - 0.00045 21.0 1.2 0.0057 17.4 0.9 2.6 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGC28765.1 - 0.00056 20.0 3.2 0.038 14.1 0.0 2.5 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EGC28765.1 - 0.0012 18.7 0.0 0.009 15.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC28765.1 - 0.0023 18.2 4.2 0.0027 17.9 0.0 2.7 3 0 0 3 3 3 1 AAA domain Cytidylate_kin2 PF13189.1 EGC28765.1 - 0.0063 16.4 1.0 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 Cytidylate kinase-like family AAA_22 PF13401.1 EGC28765.1 - 0.0082 16.2 0.2 0.036 14.2 0.0 2.3 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC28765.1 - 0.017 15.0 0.0 0.04 13.9 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Hpr_kinase_C PF07475.7 EGC28765.1 - 0.059 12.6 0.1 0.12 11.6 0.1 1.5 1 0 0 1 1 1 0 HPr Serine kinase C-terminal domain AAA PF00004.24 EGC28765.1 - 0.094 12.9 0.0 0.38 10.9 0.0 2.0 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) ResIII PF04851.10 EGC28765.1 - 0.1 12.3 0.0 0.1 12.3 0.0 2.5 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit CRISPR_Cas2 PF09827.4 EGC28765.1 - 0.19 11.8 2.7 5.7 7.1 1.1 2.8 2 0 0 2 2 2 0 CRISPR associated protein Cas2 LPP20 PF02169.11 EGC28765.1 - 0.73 9.9 4.8 3.9 7.6 0.1 2.5 2 0 0 2 2 2 0 LPP20 lipoprotein ABC_tran PF00005.22 EGC28765.1 - 2.1 8.6 5.7 0.48 10.7 0.6 2.2 2 1 0 2 2 2 0 ABC transporter AAA_13 PF13166.1 EGC28766.1 - 0.025 13.0 0.8 0.032 12.7 0.6 1.0 1 0 0 1 1 1 0 AAA domain Endotoxin_N PF03945.9 EGC28766.1 - 0.028 13.7 0.0 0.041 13.2 0.0 1.3 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain DUF3735 PF12537.3 EGC28767.1 - 0.041 13.9 1.5 0.041 13.9 1.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3735) Coiled PF05710.7 EGC28767.1 - 0.63 10.5 11.4 0.69 10.4 7.9 1.3 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC28768.1 - 0.73 10.3 9.5 0.89 10.0 6.6 1.3 1 1 0 1 1 1 0 Coiled coil adh_short_C2 PF13561.1 EGC28769.1 - 6.7e-11 42.4 0.0 3.2e-08 33.6 0.0 2.8 2 0 0 2 2 2 2 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGC28769.1 - 1.1e-09 38.4 0.0 2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC28769.1 - 0.0024 17.5 0.0 0.0042 16.7 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC28769.1 - 0.014 14.7 0.0 0.03 13.7 0.0 1.5 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family DZR PF12773.2 EGC28769.1 - 0.052 13.3 0.6 0.12 12.2 0.4 1.5 1 0 0 1 1 1 0 Double zinc ribbon NAD_binding_10 PF13460.1 EGC28769.1 - 0.081 12.9 0.0 0.17 11.8 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding FNIP PF05725.7 EGC28770.1 - 1.2e-24 85.9 43.2 3.3e-12 46.1 3.1 10.9 6 3 8 14 14 14 11 FNIP Repeat DUF1769 PF08588.5 EGC28770.1 - 0.0014 18.5 2.4 0.084 12.8 0.1 3.4 1 1 2 3 3 3 2 Protein of unknown function (DUF1769) Coiled PF05710.7 EGC28771.1 - 0.015 15.7 2.7 0.016 15.6 1.9 1.1 1 0 0 1 1 1 0 Coiled coil G-alpha PF00503.15 EGC28772.1 - 3.1e-116 388.2 3.8 3.8e-116 387.9 2.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC28772.1 - 2.9e-15 55.9 0.3 2.7e-11 43.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC28772.1 - 1.9e-06 27.2 0.8 0.0011 18.2 0.0 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC28772.1 - 0.002 18.6 0.7 0.38 11.2 0.0 3.1 1 1 1 2 2 2 1 Miro-like protein AAA_29 PF13555.1 EGC28772.1 - 0.03 13.8 0.0 0.058 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGC28772.1 - 0.048 13.6 0.1 1.7 8.6 0.1 2.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC28772.1 - 0.11 11.8 0.0 0.87 8.9 0.0 2.2 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PCMT PF01135.14 EGC28773.1 - 4.6e-60 202.7 0.0 5.7e-60 202.4 0.0 1.0 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGC28773.1 - 6.4e-11 42.8 0.1 1.1e-10 42.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC28773.1 - 4.8e-10 39.2 0.1 7.4e-10 38.6 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC28773.1 - 7.1e-06 26.4 0.0 1.5e-05 25.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC28773.1 - 4.3e-05 23.2 0.0 6.7e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC28773.1 - 4.3e-05 23.9 0.0 0.00011 22.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGC28773.1 - 0.00095 18.8 0.0 0.0013 18.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC28773.1 - 0.001 18.4 0.0 0.0017 17.7 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC28773.1 - 0.002 18.1 0.0 0.004 17.1 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC28773.1 - 0.0059 15.7 0.0 0.0087 15.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_3 PF01596.12 EGC28773.1 - 0.0062 15.6 0.0 0.0091 15.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_25 PF13649.1 EGC28773.1 - 0.014 15.7 0.0 0.03 14.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain GidB PF02527.10 EGC28773.1 - 0.026 13.6 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EGC28773.1 - 0.03 13.3 0.0 0.049 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EGC28773.1 - 0.057 12.4 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase UPF0233 PF06781.7 EGC28774.1 - 0.21 11.2 5.3 0.25 11.0 0.0 3.3 2 2 1 3 3 3 0 Uncharacterised protein family (UPF0233) F-box-like PF12937.2 EGC28775.1 - 0.00054 19.6 1.2 0.001 18.7 0.1 1.9 2 0 0 2 2 2 1 F-box-like DUF912 PF06024.7 EGC28775.1 - 3.2 7.8 17.8 1.2 9.2 3.4 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) UQ_con PF00179.21 EGC28776.1 - 4.2e-23 81.3 0.0 4.6e-23 81.1 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGC28776.1 - 0.0063 16.4 0.0 0.0087 15.9 0.0 1.3 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGC28776.1 - 0.093 12.4 0.0 0.11 12.2 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B Pkinase_Tyr PF07714.12 EGC28777.1 - 4.1e-61 206.3 0.0 6.4e-61 205.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC28777.1 - 2.1e-53 181.1 0.0 4.9e-53 179.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EGC28777.1 - 8.5e-12 44.7 0.0 2.2e-11 43.3 0.0 1.7 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 EGC28777.1 - 0.046 13.4 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family CTDII PF01556.13 EGC28778.1 - 8.4e-12 44.8 0.4 9.1e-12 44.7 0.3 1.0 1 0 0 1 1 1 1 DnaJ C terminal domain DUF3922 PF13059.1 EGC28779.1 - 0.05 13.8 0.1 0.081 13.1 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3992) CDC14 PF08045.6 EGC28779.1 - 0.067 12.3 0.1 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Cell division control protein 14, SIN component Atg14 PF10186.4 EGC28780.1 - 1.5e-18 66.8 8.0 1.5e-18 66.8 5.6 3.2 3 0 0 3 3 3 1 UV radiation resistance protein and autophagy-related subunit 14 APG6 PF04111.7 EGC28780.1 - 2.8e-10 39.7 14.0 2.8e-10 39.7 9.7 4.8 3 1 1 4 4 4 1 Autophagy protein Apg6 NEP PF10167.4 EGC28781.1 - 2.2e-38 130.5 3.9 2.2e-38 130.5 2.7 1.8 2 0 0 2 2 2 1 Uncharacterised conserved protein DUF3677 PF12432.3 EGC28783.1 - 5.3e-22 78.0 2.3 1.6e-11 44.5 0.4 4.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3677) Pkinase PF00069.20 EGC28785.1 - 5e-78 261.8 0.1 5e-78 261.8 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28785.1 - 6.8e-40 136.7 0.0 1.1e-39 136.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28785.1 - 1.2e-08 34.3 0.0 1.9e-08 33.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC28785.1 - 0.027 14.1 0.0 0.046 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PRP1_N PF06424.7 EGC28785.1 - 0.048 13.9 7.4 0.081 13.2 5.1 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DAHP_synth_1 PF00793.15 EGC28785.1 - 0.052 12.2 0.3 0.52 8.9 0.0 2.1 2 0 0 2 2 2 0 DAHP synthetase I family Daxx PF03344.10 EGC28785.1 - 0.16 10.4 11.9 0.22 9.9 8.2 1.1 1 0 0 1 1 1 0 Daxx Family YrbL-PhoP_reg PF10707.4 EGC28785.1 - 0.25 10.6 0.0 0.25 10.6 0.0 2.1 3 0 0 3 3 3 0 PhoP regulatory network protein YrbL CDC45 PF02724.9 EGC28785.1 - 1.6 6.6 14.7 2.4 6.1 10.2 1.1 1 0 0 1 1 1 0 CDC45-like protein APC_CDC26 PF10471.4 EGC28785.1 - 5 7.9 17.2 0.39 11.4 6.1 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 AAA_12 PF13087.1 EGC28786.1 - 8.3e-39 133.0 0.2 8.3e-39 133.0 0.2 2.7 2 1 1 3 3 1 1 AAA domain AAA_11 PF13086.1 EGC28786.1 - 8.9e-22 77.8 3.2 8.9e-22 77.8 2.2 4.8 3 2 0 3 3 2 1 AAA domain SAM_1 PF00536.25 EGC28786.1 - 1.1e-08 35.1 0.1 3.6e-08 33.4 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC28786.1 - 1.9e-06 27.6 0.1 6.9e-06 25.8 0.1 2.0 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_19 PF13245.1 EGC28786.1 - 5e-06 26.1 0.0 1.2e-05 24.9 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGC28786.1 - 6.6e-05 22.5 0.0 0.0051 16.4 0.0 2.3 2 0 0 2 2 2 1 AAA domain SAM_PNT PF02198.11 EGC28786.1 - 0.015 15.0 0.0 0.038 13.7 0.0 1.8 1 0 0 1 1 1 0 Sterile alpha motif (SAM)/Pointed domain AAA_33 PF13671.1 EGC28786.1 - 0.018 14.8 0.0 0.048 13.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC28786.1 - 0.026 14.4 0.0 0.06 13.3 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_22 PF13401.1 EGC28786.1 - 0.028 14.5 0.0 0.12 12.5 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGC28786.1 - 0.14 11.5 0.1 0.5 9.7 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC28786.1 - 3.3 8.5 7.8 0.53 11.1 0.1 3.8 4 1 0 4 4 4 0 AAA domain PIP5K PF01504.13 EGC28788.1 - 4.4e-59 199.6 9.1 4.4e-59 199.6 6.3 2.0 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Fz PF01392.17 EGC28790.1 - 2.9e-05 24.3 3.3 5.8e-05 23.4 2.3 1.5 1 0 0 1 1 1 1 Fz domain 7tm_2 PF00002.19 EGC28790.1 - 0.01 14.9 11.9 0.015 14.3 8.2 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) TPR_1 PF00515.23 EGC28791.1 - 1.1e-16 59.6 2.5 9.7e-06 24.9 0.2 3.4 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC28791.1 - 1e-12 47.5 2.1 1.4e-07 31.0 0.1 2.4 1 1 1 2 2 2 2 TPR repeat TPR_8 PF13181.1 EGC28791.1 - 3.3e-12 45.2 2.4 2.2e-05 23.8 0.0 3.4 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC28791.1 - 6.7e-10 38.1 2.4 0.0041 16.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC28791.1 - 3.4e-08 33.9 0.3 1.4e-06 28.8 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC28791.1 - 8.8e-07 29.0 0.1 0.00055 20.3 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC28791.1 - 9e-07 28.6 1.1 0.00014 21.8 0.1 2.7 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC28791.1 - 5.7e-06 26.1 1.9 0.055 13.4 0.1 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC28791.1 - 0.0018 18.6 0.6 4.7 7.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat ChAPs PF09295.5 EGC28791.1 - 0.0036 16.1 0.0 0.0041 15.9 0.0 1.0 1 0 0 1 1 1 1 ChAPs (Chs5p-Arf1p-binding proteins) Apc3 PF12895.2 EGC28791.1 - 0.0059 16.7 1.9 0.06 13.4 1.1 2.2 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGC28791.1 - 0.0075 16.5 0.1 0.075 13.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC28791.1 - 0.01 15.5 1.1 5.6 7.0 0.1 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGC28791.1 - 0.041 13.7 0.0 0.15 11.9 0.0 1.9 2 1 0 2 2 2 0 MIT (microtubule interacting and transport) domain FAT PF02259.18 EGC28791.1 - 0.044 12.7 0.1 0.088 11.7 0.0 1.6 1 1 0 1 1 1 0 FAT domain UPF0231 PF06062.6 EGC28791.1 - 0.078 12.8 0.0 0.32 10.9 0.0 1.8 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) Cytochrom_C1 PF02167.10 EGC28793.1 - 7.9e-80 267.6 0.0 9.2e-80 267.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome C1 family Cytochrome_CBB3 PF13442.1 EGC28793.1 - 5e-05 23.3 0.0 9.3e-05 22.5 0.0 1.5 1 0 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C PF00034.16 EGC28793.1 - 0.032 15.0 0.4 0.08 13.7 0.3 1.8 1 1 0 1 1 1 0 Cytochrome c Ribosomal_60s PF00428.14 EGC28794.1 - 1.5e-25 89.3 8.8 1.8e-25 89.1 6.1 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Holin_LLH PF09682.5 EGC28794.1 - 0.0074 16.3 0.5 0.58 10.2 0.0 2.1 2 0 0 2 2 2 2 Phage holin protein (Holin_LLH) SET PF00856.23 EGC28794.1 - 0.13 12.5 0.0 0.15 12.3 0.0 1.1 1 0 0 1 1 1 0 SET domain PepSY_2 PF13670.1 EGC28794.1 - 0.23 11.3 5.5 4.4 7.2 3.9 2.1 2 0 0 2 2 2 0 Peptidase propeptide and YPEB domain WD40 PF00400.27 EGC28795.1 - 9.3e-50 164.8 11.1 3e-10 39.5 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat Nup160 PF11715.3 EGC28795.1 - 4.2e-05 21.8 2.8 0.13 10.3 0.3 4.5 2 1 2 4 4 4 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGC28795.1 - 0.00033 19.5 0.0 0.43 9.2 0.0 3.4 2 1 1 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EGC28795.1 - 0.03 12.6 0.0 4.4 5.5 0.0 2.7 3 0 0 3 3 3 0 Cytochrome D1 heme domain MaoC_dehydratas PF01575.14 EGC28796.1 - 8.7e-30 102.6 0.0 2.3e-29 101.2 0.0 1.6 2 0 0 2 2 2 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGC28796.1 - 1.1e-10 41.3 0.0 1.6e-09 37.5 0.0 2.1 2 0 0 2 2 2 1 N-terminal half of MaoC dehydratase zf-AN1 PF01428.11 EGC28798.1 - 1.1e-11 44.4 7.5 1.1e-11 44.4 5.2 2.1 2 1 0 2 2 2 1 AN1-like Zinc finger zf-A20 PF01754.11 EGC28798.1 - 2.2e-10 39.9 5.7 2.2e-10 39.9 3.9 1.9 2 0 0 2 2 2 1 A20-like zinc finger DCX PF03607.12 EGC28799.1 - 7.4e-35 118.3 0.4 2.4e-17 62.2 0.0 2.2 2 0 0 2 2 2 2 Doublecortin UB2H PF14814.1 EGC28799.1 - 0.05 13.3 0.2 9.8 5.9 0.0 2.2 2 0 0 2 2 2 0 Bifunctional transglycosylase second domain Pas_Saposin PF09016.5 EGC28799.1 - 0.081 12.9 0.0 1.3 9.0 0.0 2.2 2 0 0 2 2 2 0 Pas factor saposin fold AAA_23 PF13476.1 EGC28799.1 - 0.081 13.2 0.8 0.61 10.3 0.1 2.1 2 0 0 2 2 2 0 AAA domain RhoGEF PF00621.15 EGC28800.1 - 7.9e-42 143.1 8.8 2.5e-41 141.5 6.1 1.9 1 0 0 1 1 1 1 RhoGEF domain CH PF00307.26 EGC28800.1 - 5.8e-07 29.5 0.3 2.8e-06 27.3 0.1 2.2 2 0 0 2 2 2 1 Calponin homology (CH) domain IQ PF00612.22 EGC28800.1 - 0.00055 19.3 0.7 0.0013 18.2 0.5 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif FAM70 PF14967.1 EGC28800.1 - 0.37 9.9 6.0 0.92 8.6 4.1 1.6 1 0 0 1 1 1 0 FAM70 protein Pox_A28 PF04584.9 EGC28801.1 - 0.034 14.0 5.2 0.047 13.5 3.4 1.4 1 1 0 1 1 1 0 Poxvirus A28 family TRAPP PF04051.11 EGC28802.1 - 1.2e-39 135.2 0.2 1.4e-39 135.0 0.1 1.1 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Synaptonemal_3 PF15191.1 EGC28802.1 - 0.11 12.1 0.5 2.8 7.7 0.0 2.8 2 1 1 3 3 3 0 Synaptonemal complex central element protein 3 Usp PF00582.21 EGC28803.1 - 6.8e-13 49.0 0.0 7.4e-13 48.8 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family 2-Hacid_dh PF00389.25 EGC28803.1 - 0.12 11.8 0.0 0.2 11.1 0.0 1.5 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain Cpn60_TCP1 PF00118.19 EGC28804.1 - 1.7e-156 521.6 6.6 2e-156 521.4 4.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family FNIP PF05725.7 EGC28805.1 - 6.6e-19 67.5 31.6 6.1e-08 32.4 0.1 7.9 4 2 2 7 7 7 6 FNIP Repeat RhoGAP PF00620.22 EGC28806.1 - 3e-45 153.5 0.0 7.3e-45 152.2 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain IPK PF03770.11 EGC28806.1 - 1.1e-44 152.4 0.0 2e-44 151.6 0.0 1.4 1 0 0 1 1 1 1 Inositol polyphosphate kinase CRAL_TRIO_2 PF13716.1 EGC28806.1 - 5.3e-40 136.7 3.1 5.3e-40 136.7 2.2 2.4 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EGC28806.1 - 7.8e-12 44.9 1.2 1.5e-11 44.0 0.8 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain DUF2810 PF10928.3 EGC28806.1 - 0.033 13.9 0.0 0.079 12.7 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2810) Pkinase PF00069.20 EGC28807.1 - 5.2e-54 183.1 0.0 5.6e-53 179.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28807.1 - 8.2e-54 182.3 0.0 2e-53 181.0 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC28807.1 - 0.009 14.9 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC28807.1 - 0.029 14.0 0.0 0.045 13.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family PAT1 PF09770.4 EGC28807.1 - 3.1 5.9 45.3 5.2 5.1 31.4 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Herpes_UL73 PF03554.8 EGC28808.1 - 0.013 15.2 0.2 0.021 14.6 0.1 1.4 1 1 0 1 1 1 0 UL73 viral envelope glycoprotein Methyltransf_22 PF13383.1 EGC28809.1 - 0.065 12.7 0.2 0.53 9.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Laminin_EGF PF00053.19 EGC28810.1 - 5.1e-05 23.1 19.8 0.032 14.1 3.8 2.6 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC28810.1 - 0.0016 18.5 33.0 0.13 12.4 8.5 2.8 2 0 0 2 2 2 2 EGF-like domain Lamp PF01299.12 EGC28810.1 - 0.03 13.4 0.5 0.03 13.4 0.3 2.2 2 1 0 2 2 2 0 Lysosome-associated membrane glycoprotein (Lamp) SKG6 PF08693.5 EGC28810.1 - 0.056 12.7 3.5 0.11 11.8 2.4 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Gamma-thionin PF00304.15 EGC28810.1 - 3.9 7.5 17.2 0.25 11.3 1.9 2.5 2 0 0 2 2 2 0 Gamma-thionin family EGF_2 PF07974.8 EGC28811.1 - 0.0068 16.5 15.1 0.0068 16.5 10.5 2.3 2 0 0 2 2 2 1 EGF-like domain TT_ORF1 PF02956.9 EGC28812.1 - 0.029 12.8 8.3 0.033 12.6 5.7 1.2 1 0 0 1 1 1 0 TT viral orf 1 DUF912 PF06024.7 EGC28812.1 - 10 6.2 12.6 97 3.1 8.7 2.4 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MIP-T3 PF10243.4 EGC28813.1 - 0.49 8.7 91.6 0.022 13.2 32.3 2.3 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Histone PF00125.19 EGC28814.1 - 8.7e-13 48.2 0.3 1.1e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC28814.1 - 0.00029 20.8 0.0 0.00044 20.2 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Phospholamban PF04272.9 EGC28815.1 - 0.072 12.5 2.6 0.1 12.0 1.8 1.3 1 0 0 1 1 1 0 Phospholamban ABC_membrane PF00664.18 EGC28816.1 - 1.3e-53 182.1 45.3 1.6e-27 96.6 14.5 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC28816.1 - 9.2e-49 165.2 0.1 2e-28 99.3 0.0 3.1 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EGC28816.1 - 7.2e-12 45.0 1.7 0.00028 20.2 0.0 4.2 2 2 2 4 4 4 3 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGC28816.1 - 3.5e-06 27.5 5.5 0.0057 17.0 0.1 3.5 3 0 0 3 3 3 2 AAA domain AAA_29 PF13555.1 EGC28816.1 - 4.7e-06 26.0 0.1 0.059 12.9 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain FtsK_SpoIIIE PF01580.13 EGC28816.1 - 0.00011 21.7 0.0 0.18 11.2 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family Miro PF08477.8 EGC28816.1 - 0.00013 22.4 0.1 0.14 12.6 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein MMR_HSR1 PF01926.18 EGC28816.1 - 0.00063 19.6 0.7 0.97 9.4 0.1 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EGC28816.1 - 0.00081 20.1 1.0 0.29 11.9 0.2 3.1 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC28816.1 - 0.00086 18.5 0.1 0.22 10.6 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC28816.1 - 0.0016 17.8 0.0 0.11 11.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC28816.1 - 0.003 17.6 0.2 1 9.5 0.0 3.1 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGC28816.1 - 0.0033 16.3 0.1 1.5 7.6 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_18 PF13238.1 EGC28816.1 - 0.0041 17.4 0.6 0.43 10.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EGC28816.1 - 0.0066 16.0 0.2 0.93 9.1 0.0 2.7 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 DUF87 PF01935.12 EGC28816.1 - 0.014 15.2 3.7 0.73 9.5 0.2 3.0 3 0 0 3 3 2 0 Domain of unknown function DUF87 RNA_helicase PF00910.17 EGC28816.1 - 0.017 15.3 0.5 9.2 6.4 0.0 3.3 4 0 0 4 4 2 0 RNA helicase AAA_16 PF13191.1 EGC28816.1 - 0.028 14.4 0.9 3.4 7.6 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGC28816.1 - 0.034 13.2 1.1 5.4 6.0 0.1 2.3 2 0 0 2 2 2 0 Zeta toxin AAA_19 PF13245.1 EGC28816.1 - 0.043 13.5 0.2 0.21 11.3 0.0 2.1 2 0 0 2 2 2 0 Part of AAA domain PduV-EutP PF10662.4 EGC28816.1 - 0.044 13.2 0.3 3.2 7.2 0.0 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ArgK PF03308.11 EGC28816.1 - 0.073 11.8 0.1 0.63 8.7 0.0 2.0 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EGC28816.1 - 0.079 12.6 2.4 15 5.2 0.1 3.3 3 0 0 3 3 3 0 NTPase ResIII PF04851.10 EGC28816.1 - 0.086 12.6 2.0 12 5.7 0.0 3.4 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit AAA_33 PF13671.1 EGC28816.1 - 0.1 12.4 0.2 13 5.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGC28816.1 - 0.11 12.1 2.3 7.7 6.2 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B ATP-synt_ab PF00006.20 EGC28816.1 - 0.12 11.8 1.3 3.3 7.1 0.1 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Sigma54_activat PF00158.21 EGC28816.1 - 0.12 11.8 0.0 5.3 6.4 0.0 2.3 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_30 PF13604.1 EGC28816.1 - 0.52 9.8 0.1 22 4.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGC28816.1 - 0.63 9.4 3.1 0.61 9.5 0.2 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain ERM PF00769.14 EGC28818.1 - 0.00096 18.7 51.4 0.0014 18.2 20.0 2.2 1 1 1 2 2 2 2 Ezrin/radixin/moesin family CTP_transf_3 PF02348.14 EGC28819.1 - 4.3 6.8 6.7 6.5 6.3 4.6 1.3 1 1 0 1 1 1 0 Cytidylyltransferase TACC PF05010.9 EGC28820.1 - 0.003 17.3 22.6 1.1 8.9 8.7 2.1 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC) Hemolysin_N PF12563.3 EGC28820.1 - 0.049 13.0 4.6 0.06 12.7 3.0 1.3 1 1 0 1 1 1 0 Hemolytic toxin N terminal Penicillinase_R PF03965.11 EGC28820.1 - 0.061 13.4 0.3 0.061 13.4 0.2 2.3 3 0 0 3 3 3 0 Penicillinase repressor DUF4162 PF13732.1 EGC28820.1 - 7.4 7.1 11.8 2.9 8.4 1.0 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF4162) FNIP PF05725.7 EGC28821.1 - 2.2e-103 337.9 42.7 3.3e-15 55.7 2.4 9.3 7 2 2 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC28821.1 - 0.2 11.6 27.2 1.6 8.7 0.2 9.9 4 3 10 14 14 14 0 Protein of unknown function (DUF1769) Mito_carr PF00153.22 EGC28822.1 - 3.4e-69 228.6 2.5 3.8e-22 77.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein PTEN_C2 PF10409.4 EGC28823.1 - 1.8e-20 73.0 4.7 1.2e-16 60.6 0.0 2.7 1 1 1 2 2 2 2 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 EGC28823.1 - 2.6e-05 23.8 0.2 2.6e-05 23.8 0.1 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC28823.1 - 5.3e-05 22.6 0.0 0.00015 21.1 0.0 1.8 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC28823.1 - 6.6e-05 23.2 1.5 0.00012 22.3 0.1 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGC28823.1 - 0.12 12.4 0.2 0.12 12.4 0.1 2.8 3 1 0 3 3 3 0 Inositol hexakisphosphate OmpH PF03938.9 EGC28824.1 - 5.8 6.8 33.5 7.8 6.4 23.2 1.1 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) EXS PF03124.9 EGC28827.1 - 0.018 14.0 3.6 0.024 13.6 2.5 1.1 1 0 0 1 1 1 0 EXS family DUF4401 PF14351.1 EGC28827.1 - 0.031 13.2 5.9 0.056 12.4 3.7 1.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) MARVEL PF01284.18 EGC28827.1 - 0.052 13.3 1.3 0.5 10.1 0.9 2.2 1 1 0 1 1 1 0 Membrane-associating domain PRY PF13765.1 EGC28827.1 - 0.07 12.6 0.1 5.5 6.5 0.0 2.3 2 0 0 2 2 2 0 SPRY-associated domain 7TMR-DISM_7TM PF07695.6 EGC28827.1 - 0.09 12.4 9.9 0.18 11.4 6.8 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF3357 PF11837.3 EGC28827.1 - 0.15 11.9 5.5 0.23 11.3 0.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF3357) CD20 PF04103.10 EGC28827.1 - 0.25 11.2 6.6 21 5.0 4.2 3.0 1 1 1 2 2 2 0 CD20-like family Polysacc_synt PF01943.12 EGC28827.1 - 0.42 9.8 7.5 2.2 7.5 5.2 2.1 1 1 0 1 1 1 0 Polysaccharide biosynthesis protein DUF4149 PF13664.1 EGC28827.1 - 1 9.4 5.2 1.7 8.7 0.2 2.4 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) YfhO PF09586.5 EGC28827.1 - 1.1 7.1 7.5 4 5.3 5.2 1.8 1 1 0 1 1 1 0 Bacterial membrane protein YfhO ABC2_membrane_4 PF12730.2 EGC28827.1 - 1.6 7.8 7.3 20 4.2 4.5 2.2 1 1 0 1 1 1 0 ABC-2 family transporter protein TPT PF03151.11 EGC28827.1 - 3.3 7.3 7.3 1.8 8.1 1.4 2.1 2 0 0 2 2 2 0 Triose-phosphate Transporter family DUF1980 PF09323.5 EGC28827.1 - 6.3 6.4 22.8 1.2 8.8 5.2 2.9 1 1 2 3 3 3 0 Domain of unknown function (DUF1980) EphA2_TM PF14575.1 EGC28827.1 - 8.3 6.8 6.8 43 4.5 0.0 3.6 1 1 3 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain HrpJ PF07201.6 EGC28829.1 - 2.5 8.1 6.2 0.55 10.2 0.8 2.2 1 1 2 3 3 3 0 HrpJ-like domain Myb_DNA-binding PF00249.26 EGC28830.1 - 1.4e-12 47.4 0.2 2.8e-12 46.4 0.2 1.6 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC28830.1 - 0.0011 18.9 0.3 0.0037 17.3 0.1 2.0 2 0 0 2 2 2 1 Myb-like DNA-binding domain Phage_C PF12025.3 EGC28830.1 - 0.1 12.5 0.1 0.26 11.2 0.1 1.6 1 0 0 1 1 1 0 Phage protein C PI3K_1B_p101 PF10486.4 EGC28832.1 - 0.28 8.7 4.4 0.29 8.6 3.0 1.2 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DARPP-32 PF05395.7 EGC28832.1 - 3.7 7.6 13.5 1.9 8.6 8.0 1.5 1 1 0 1 1 1 0 Protein phosphatase inhibitor 1/DARPP-32 FNIP_M PF14637.1 EGC28833.1 - 1.3e-68 231.1 3.3 2.4e-68 230.2 2.3 1.4 1 0 0 1 1 1 1 Folliculin-interacting protein middle domain FNIP_N PF14636.1 EGC28833.1 - 3.4e-20 72.8 0.0 3.4e-20 72.8 0.0 3.5 3 0 0 3 3 3 1 Folliculin-interacting protein N-terminus FNIP_C PF14638.1 EGC28833.1 - 2.8e-18 65.9 0.0 9e-18 64.3 0.0 1.9 1 1 0 1 1 1 1 Folliculin-interacting protein C-terminus BSD PF03909.12 EGC28834.1 - 1.1e-11 44.2 4.7 1.5e-11 43.8 1.7 2.5 2 0 0 2 2 2 1 BSD domain Peptidase_C26 PF07722.8 EGC28835.1 - 1.6e-25 89.8 0.0 2.1e-25 89.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EGC28835.1 - 9.8e-09 34.9 0.0 1.5e-08 34.3 0.0 1.2 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGC28836.1 - 8.8e-33 113.5 0.0 1.1e-32 113.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EGC28836.1 - 7.5e-10 38.5 0.0 1.1e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I zf-DHHC PF01529.15 EGC28837.1 - 1.4e-23 83.1 27.5 1.4e-23 83.1 19.1 2.6 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF1272 PF06906.6 EGC28837.1 - 0.36 10.7 4.8 0.92 9.4 3.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-AD PF07776.10 EGC28837.1 - 1.2 9.1 8.9 4.5 7.3 6.1 2.0 1 1 0 1 1 1 0 Zinc-finger associated domain (zf-AD) EB PF01683.13 EGC28838.1 - 0.0068 16.4 4.8 0.0068 16.4 3.4 7.7 2 2 6 8 8 8 6 EB module FNIP PF05725.7 EGC28840.1 - 1.9e-64 213.3 44.8 3.6e-13 49.2 0.5 8.9 5 2 5 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 EGC28840.1 - 0.0018 18.1 8.3 6.6 6.7 0.1 5.6 4 1 2 6 6 6 3 Protein of unknown function (DUF1769) F-box-like_2 PF13013.1 EGC28840.1 - 0.04 13.6 0.4 1.6 8.5 0.0 3.1 3 0 0 3 3 3 0 F-box-like domain DUF3752 PF12572.3 EGC28841.1 - 3.7e-11 43.3 12.7 3.7e-11 43.3 8.8 2.4 2 1 0 2 2 2 1 Protein of unknown function (DUF3752) Vma12 PF11712.3 EGC28841.1 - 5.6 6.6 6.1 2.6 7.7 1.5 2.5 2 1 0 2 2 2 0 Endoplasmic reticulum-based factor for assembly of V-ATPase Claudin_2 PF13903.1 EGC28842.1 - 3.3e-08 33.3 6.7 2.3e-07 30.6 4.6 2.2 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CAAD PF14159.1 EGC28842.1 - 0.017 14.7 2.2 0.017 14.7 1.6 2.7 3 0 0 3 3 3 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DctQ PF04290.7 EGC28842.1 - 0.19 11.4 0.0 0.19 11.4 0.0 2.7 1 1 2 3 3 3 0 Tripartite ATP-independent periplasmic transporters, DctQ component Claudin_2 PF13903.1 EGC28843.1 - 0.00051 19.7 4.5 0.00051 19.7 3.1 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction PMP22_Claudin PF00822.15 EGC28843.1 - 0.013 15.1 6.9 0.64 9.6 0.7 2.3 1 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF202 PF02656.10 EGC28843.1 - 0.1 12.8 6.8 2.7 8.2 0.9 3.5 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF1494 PF07379.6 EGC28843.1 - 0.37 10.6 2.9 0.57 10.0 1.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1494) Cation_ATPase_C PF00689.16 EGC28843.1 - 1 8.8 17.4 0.3 10.5 0.5 2.3 1 1 0 2 2 2 0 Cation transporting ATPase, C-terminus DUF4064 PF13273.1 EGC28843.1 - 3.6 7.7 15.6 4.5 7.4 4.0 3.7 1 1 3 4 4 4 0 Protein of unknown function (DUF4064) Imm10 PF15562.1 EGC28843.1 - 8.4 6.2 9.8 3.6 7.4 0.1 3.2 3 0 0 3 3 3 0 Immunity protein 10 RRM_1 PF00076.17 EGC28844.1 - 5.7e-19 67.5 0.9 8.9e-19 66.8 0.6 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC28844.1 - 4.7e-12 45.7 0.1 8.6e-12 44.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC28844.1 - 1.1e-08 34.7 0.1 1.9e-08 34.0 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF3664 PF12406.3 EGC28844.1 - 0.071 13.7 2.2 0.13 12.9 0.1 2.2 2 0 0 2 2 2 0 Surface protein NDUF_B4 PF07225.7 EGC28845.1 - 0.056 13.2 0.6 0.93 9.3 0.2 2.2 2 0 0 2 2 2 0 NADH-ubiquinone oxidoreductase B15 subunit (NDUFB4) Kdo_hydroxy PF11004.3 EGC28845.1 - 0.12 11.3 2.4 0.13 11.2 0.2 1.9 2 0 0 2 2 2 0 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase POX PF07526.6 EGC28845.1 - 6.2 7.0 26.4 1.2 9.3 2.0 3.0 2 1 1 3 3 3 0 Associated with HOX Band_7 PF01145.20 EGC28846.1 - 1.3e-25 90.3 2.7 1.7e-25 89.9 1.9 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family YdfA_immunity PF12127.3 EGC28846.1 - 0.0051 15.7 2.2 0.007 15.3 1.5 1.2 1 0 0 1 1 1 1 SigmaW regulon antibacterial SnoaL_2 PF12680.2 EGC28847.1 - 4.2e-06 27.0 0.0 5.1e-06 26.8 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGC28847.1 - 0.00047 19.7 0.1 0.0019 17.8 0.1 1.7 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 EGC28847.1 - 0.0048 17.0 0.0 0.0053 16.9 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3271 PF11675.3 EGC28847.1 - 0.035 13.2 0.2 0.036 13.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) HopJ PF08888.6 EGC28847.1 - 0.065 13.2 0.0 0.11 12.5 0.0 1.4 1 0 0 1 1 1 0 HopJ type III effector protein Pkinase_Tyr PF07714.12 EGC28848.1 - 2.7e-90 301.9 0.0 5.6e-60 202.6 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGC28848.1 - 1.4e-71 240.6 0.0 3.3e-49 167.3 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 EGC28848.1 - 0.00013 21.0 0.0 0.11 11.4 0.0 2.5 3 0 0 3 3 3 2 Kinase-like Kdo PF06293.9 EGC28848.1 - 0.0018 17.3 0.1 0.15 11.0 0.0 2.3 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC28848.1 - 0.3 10.8 0.0 2.4 7.8 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family CH PF00307.26 EGC28849.1 - 1.1e-12 47.9 0.1 6.5e-12 45.4 0.1 2.4 1 0 0 1 1 1 1 Calponin homology (CH) domain GAS2 PF02187.12 EGC28849.1 - 6.9e-08 32.1 0.1 1.7e-07 30.8 0.0 1.6 1 0 0 1 1 1 1 Growth-Arrest-Specific Protein 2 Domain CAMSAP_CH PF11971.3 EGC28849.1 - 0.025 14.1 0.0 0.025 14.1 0.0 3.1 3 0 0 3 3 3 0 CAMSAP CH domain DUF3106 PF11304.3 EGC28850.1 - 0.075 13.4 4.5 0.061 13.7 1.8 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) Phage_Nu1 PF07471.7 EGC28850.1 - 0.17 11.3 7.2 2.7 7.4 3.4 2.4 2 1 0 2 2 2 0 Phage DNA packaging protein Nu1 DUF4200 PF13863.1 EGC28850.1 - 0.3 11.0 21.8 0.22 11.4 13.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4200) Secretin_N_2 PF07655.8 EGC28850.1 - 3.7 8.0 34.5 6.7 7.1 8.2 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain CHZ PF09649.5 EGC28851.1 - 0.015 14.5 2.6 0.015 14.5 1.8 1.8 2 0 0 2 2 2 0 Histone chaperone domain CHZ DUF755 PF05501.6 EGC28851.1 - 0.08 13.0 12.9 0.14 12.2 8.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Eapp_C PF10238.4 EGC28851.1 - 3 7.7 15.2 7.9 6.3 10.6 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein E7 PF00527.13 EGC28851.1 - 5.8 7.1 6.1 1.5 9.0 1.7 1.8 1 1 1 2 2 2 0 E7 protein, Early protein TIG PF01833.19 EGC28852.1 - 1.4e-12 47.4 49.7 9.7e-06 25.4 1.1 7.6 7 0 0 7 7 7 5 IPT/TIG domain CARDB PF07705.6 EGC28852.1 - 0.011 15.8 1.9 0.011 15.8 1.3 3.8 5 0 0 5 5 5 0 CARDB Ras PF00071.17 EGC28854.1 - 1.5e-64 216.2 0.9 1.7e-64 216.0 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28854.1 - 9.1e-20 71.3 0.0 1.6e-19 70.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC28854.1 - 1.2e-16 60.5 0.1 1.4e-16 60.1 0.1 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC28854.1 - 2e-06 27.0 0.1 2.4e-06 26.8 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC28854.1 - 7.2e-06 25.5 0.3 1.5e-05 24.4 0.2 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC28854.1 - 2.7e-05 24.0 0.1 4.7e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EGC28854.1 - 4.5e-05 23.6 0.1 0.0052 16.9 0.0 2.1 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) SRPRB PF09439.5 EGC28854.1 - 0.00017 20.8 0.1 0.00027 20.2 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGC28854.1 - 0.00054 20.1 0.0 0.00086 19.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EGC28854.1 - 0.0022 17.3 0.1 0.015 14.5 0.1 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_16 PF13191.1 EGC28854.1 - 0.0067 16.4 0.1 0.04 13.8 0.0 2.0 2 1 0 2 2 2 1 AAA ATPase domain DUF258 PF03193.11 EGC28854.1 - 0.025 13.7 0.1 0.058 12.5 0.0 1.6 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGC28854.1 - 0.031 13.9 0.0 0.052 13.2 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_29 PF13555.1 EGC28854.1 - 0.037 13.5 0.0 0.11 11.9 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain G-alpha PF00503.15 EGC28854.1 - 0.57 8.8 5.8 5.8 5.4 1.0 2.8 1 1 1 2 2 2 0 G-protein alpha subunit DUF2246 PF10229.4 EGC28855.1 - 1.7e-27 96.4 1.5 2.6e-26 92.5 1.0 1.9 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2246) GrpE PF01025.14 EGC28856.1 - 7.1e-32 110.2 15.4 4.3e-30 104.4 10.7 2.1 1 1 0 1 1 1 1 GrpE DASH_Hsk3 PF08227.6 EGC28856.1 - 0.019 15.1 0.4 2.4 8.4 0.0 2.9 2 1 1 3 3 3 0 DASH complex subunit Hsk3 like Spc7 PF08317.6 EGC28856.1 - 0.038 12.6 8.9 0.051 12.2 6.2 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein DUF4286 PF14114.1 EGC28856.1 - 0.044 14.0 3.3 0.13 12.4 1.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4286) Inositol_P PF00459.20 EGC28856.1 - 0.36 10.0 1.7 0.46 9.7 1.2 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family DUF4363 PF14276.1 EGC28856.1 - 2.1 8.0 6.0 3.2 7.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) DUF4085 PF13315.1 EGC28856.1 - 3.5 6.9 11.2 1.8 7.9 4.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4085) IncA PF04156.9 EGC28856.1 - 4.3 6.8 9.3 6.6 6.2 6.5 1.3 1 0 0 1 1 1 0 IncA protein EF-hand_7 PF13499.1 EGC28857.1 - 3e-25 88.1 10.4 8.5e-13 48.2 0.6 3.0 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC28857.1 - 1.6e-20 70.8 4.5 0.00023 20.2 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC28857.1 - 6e-18 63.0 2.7 0.00087 18.9 0.1 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC28857.1 - 5.8e-16 57.0 3.7 4.2e-05 22.7 0.0 4.3 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC28857.1 - 4.7e-11 42.1 4.7 5e-06 26.0 0.8 3.9 3 1 1 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC28857.1 - 1.7e-08 34.4 1.5 0.01 15.8 0.1 3.0 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC28857.1 - 0.0025 17.4 0.7 5.2 6.8 0.0 3.1 2 1 1 3 3 3 2 EF hand Dimerisation PF08100.6 EGC28857.1 - 0.0044 16.8 0.2 3.3 7.6 0.0 3.0 1 1 2 3 3 3 1 Dimerisation domain Gag_p24 PF00607.15 EGC28857.1 - 0.045 13.2 0.1 0.054 13.0 0.1 1.2 1 0 0 1 1 1 0 gag gene protein p24 (core nucleocapsid protein) DUF3811 PF11656.3 EGC28857.1 - 0.053 13.5 3.7 1.6 8.8 1.4 2.4 2 0 0 2 2 2 0 YjbD family (DUF3811) PMBR PF09373.5 EGC28857.1 - 0.054 13.4 0.2 26 4.9 0.0 4.0 4 1 1 5 5 5 0 Pseudomurein-binding repeat Paramyx_P_V_C PF03210.8 EGC28857.1 - 0.085 12.7 3.2 0.075 12.8 1.5 1.6 1 1 1 2 2 2 0 Paramyxovirus P/V phosphoprotein C-terminal NPR3 PF03666.8 EGC28857.1 - 0.1 11.1 1.7 0.23 9.9 0.2 1.8 1 1 1 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF2497 PF10691.4 EGC28857.1 - 0.13 12.2 1.2 0.58 10.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2497) DUF515 PF04415.7 EGC28857.1 - 0.2 9.8 5.7 0.17 10.0 3.3 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) Synaptobrevin PF00957.16 EGC28857.1 - 3.5 7.2 7.0 1.1 8.8 0.1 2.6 2 1 0 2 2 2 0 Synaptobrevin DUF1014 PF06244.7 EGC28857.1 - 9.4 6.4 7.9 6.6 6.9 2.9 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1014) FNIP PF05725.7 EGC28858.1 - 5.3e-29 99.9 27.8 3.5e-06 26.8 0.2 8.8 4 2 5 10 10 10 8 FNIP Repeat zf-B_box PF00643.19 EGC28858.1 - 1.4e-05 24.9 2.8 2.2e-05 24.2 2.0 1.3 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC28858.1 - 0.14 11.8 2.4 0.32 10.7 1.7 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) MitMem_reg PF13012.1 EGC28858.1 - 0.33 11.0 10.1 4.1 7.5 4.3 2.4 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Alg6_Alg8 PF03155.10 EGC28859.1 - 2.3e-147 491.6 44.8 3.1e-147 491.2 31.1 1.0 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family Ank_2 PF12796.2 EGC28861.1 - 1.5e-09 38.0 3.7 0.0023 18.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC28861.1 - 2e-05 24.3 6.7 0.55 10.6 0.0 6.6 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 EGC28861.1 - 0.0021 18.5 3.1 0.98 10.0 0.0 4.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Cyclin_N PF00134.18 EGC28862.1 - 1.1e-22 79.9 0.5 7.9e-20 70.7 0.1 2.1 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC28862.1 - 1.6e-06 27.9 0.8 3.6e-05 23.6 0.1 2.3 2 1 0 2 2 2 1 Cyclin, C-terminal domain TFIIB PF00382.14 EGC28862.1 - 0.003 17.3 0.0 0.035 13.8 0.0 2.2 2 0 0 2 2 2 1 Transcription factor TFIIB repeat DUF2373 PF10180.4 EGC28862.1 - 0.11 12.0 0.5 2.2 7.8 0.1 2.6 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) Prefoldin PF02996.12 EGC28864.1 - 2.5e-26 91.6 3.7 4.4e-26 90.8 2.6 1.4 1 0 0 1 1 1 1 Prefoldin subunit PhoU_div PF01865.11 EGC28864.1 - 0.022 13.9 1.7 0.071 12.2 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function DUF47 SIMPL PF04402.9 EGC28864.1 - 0.028 14.3 0.5 0.028 14.3 0.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF541) MazG PF03819.12 EGC28864.1 - 0.1 12.5 1.6 3 7.8 0.0 2.9 3 0 0 3 3 3 0 MazG nucleotide pyrophosphohydrolase domain Filamin PF00630.14 EGC28864.1 - 0.11 13.0 0.1 0.18 12.3 0.1 1.4 1 0 0 1 1 1 0 Filamin/ABP280 repeat PRANC PF09372.5 EGC28864.1 - 0.11 12.4 1.4 0.24 11.3 1.0 1.7 1 0 0 1 1 1 0 PRANC domain Band_7 PF01145.20 EGC28864.1 - 0.46 10.3 7.6 3.6 7.4 1.6 2.1 2 0 0 2 2 2 0 SPFH domain / Band 7 family KLRAQ PF10205.4 EGC28864.1 - 3.1 7.9 10.2 6.9 6.7 0.5 2.3 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein Med2 PF11214.3 EGC28864.1 - 5.7 7.0 12.7 0.24 11.4 2.6 2.4 2 1 0 2 2 2 0 Mediator complex subunit 2 APH PF01636.18 EGC28866.1 - 1.8e-13 50.7 0.0 2.7e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGC28866.1 - 0.0095 14.9 0.4 0.014 14.4 0.3 1.5 1 1 0 1 1 1 1 Fructosamine kinase FbpA PF05833.6 EGC28866.1 - 0.026 13.0 0.1 0.036 12.6 0.1 1.2 1 0 0 1 1 1 0 Fibronectin-binding protein A N-terminus (FbpA) RRM_1 PF00076.17 EGC28866.1 - 0.031 13.9 0.0 0.12 12.0 0.0 2.0 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CSL PF05207.8 EGC28867.1 - 9e-22 76.3 4.6 1.6e-21 75.5 3.2 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGC28867.1 - 7.1e-20 70.5 1.7 1e-19 70.0 1.2 1.2 1 0 0 1 1 1 1 DnaJ domain DUF2250 PF10007.4 EGC28867.1 - 0.043 13.7 0.3 0.059 13.2 0.2 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) zinc_ribbon_5 PF13719.1 EGC28867.1 - 0.68 9.5 3.6 0.49 10.0 1.2 1.8 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGC28867.1 - 0.95 9.2 3.8 0.75 9.5 1.4 1.8 2 0 0 2 2 2 0 zinc-ribbon domain SNF2_N PF00176.18 EGC28868.1 - 4.4e-80 268.6 0.0 1e-79 267.4 0.0 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain SLIDE PF09111.5 EGC28868.1 - 2.5e-40 136.8 5.7 2.5e-40 136.8 3.9 2.7 3 0 0 3 3 3 1 SLIDE Helicase_C PF00271.26 EGC28868.1 - 5.5e-16 58.2 0.0 2.7e-15 55.9 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HAND PF09110.6 EGC28868.1 - 1.6e-09 38.1 6.5 1.6e-09 38.1 4.5 4.8 4 2 0 4 4 4 1 HAND Myb_DNA-binding PF00249.26 EGC28868.1 - 1.2e-07 31.7 0.0 0.00083 19.3 0.0 3.2 2 1 0 2 2 2 2 Myb-like DNA-binding domain DEAD PF00270.24 EGC28868.1 - 7.3e-06 25.5 0.0 4.4e-05 23.0 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase RCC1 PF00415.13 EGC28869.1 - 1.1e-44 150.4 2.3 1.6e-10 40.9 0.0 6.0 5 1 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC28869.1 - 1.7e-27 94.3 17.8 4e-08 32.6 0.1 5.3 5 0 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat Ank_4 PF13637.1 EGC28869.1 - 7.9e-13 48.5 0.1 7e-08 32.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC28869.1 - 7.8e-09 35.5 0.0 2e-08 34.2 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGC28869.1 - 3e-07 29.9 0.1 1.5e-05 24.5 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EGC28869.1 - 9.1e-07 29.1 0.1 2.1e-06 27.9 0.1 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC28869.1 - 7.1e-06 25.7 0.1 0.00014 21.7 0.0 3.0 3 0 0 3 3 3 1 Ankyrin repeat Guanylate_cyc PF00211.15 EGC28870.1 - 9.9e-73 243.4 0.1 7.6e-44 149.2 0.0 2.3 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TRIQK PF15168.1 EGC28870.1 - 3.3 7.6 10.2 0.066 13.1 0.5 2.9 2 0 0 2 2 2 0 Triple QxxK/R motif-containing protein family TIG PF01833.19 EGC28871.1 - 3.1e-05 23.8 11.6 0.0014 18.6 0.9 4.4 4 0 0 4 4 4 2 IPT/TIG domain PAP_assoc PF03828.14 EGC28871.1 - 0.0026 17.6 0.2 0.0026 17.6 0.2 2.4 2 0 0 2 2 2 1 Cid1 family poly A polymerase EGF_2 PF07974.8 EGC28871.1 - 0.003 17.6 44.0 0.031 14.4 6.0 3.8 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.19 EGC28871.1 - 0.049 13.5 30.2 3.3 7.7 2.7 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) DUF972 PF06156.8 EGC28871.1 - 0.07 13.4 6.4 1.8 8.9 0.8 3.3 2 0 0 2 2 2 0 Protein of unknown function (DUF972) DUF3006 PF11213.3 EGC28871.1 - 0.36 10.5 3.0 0.2 11.4 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3006) PMP1_2 PF08114.6 EGC28871.1 - 1.6 8.2 2.4 3.4 7.2 1.6 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Ctf8 PF09696.5 EGC28872.1 - 4.6e-13 49.0 0.5 2.5e-12 46.6 0.4 2.0 1 1 0 1 1 1 1 Ctf8 CASP_C PF08172.7 EGC28872.1 - 0.1 11.6 0.7 0.16 10.9 0.5 1.3 1 1 0 1 1 1 0 CASP C terminal CTP_transf_2 PF01467.21 EGC28873.1 - 7.3e-16 58.6 0.0 8.8e-16 58.3 0.0 1.1 1 0 0 1 1 1 1 Cytidylyltransferase Enolase_C PF00113.17 EGC28876.1 - 2e-91 306.0 0.2 2.2e-91 305.9 0.1 1.0 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain MAAL_C PF07476.6 EGC28876.1 - 1.7e-05 23.9 0.0 2.4e-05 23.4 0.0 1.3 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus MR_MLE PF01188.16 EGC28876.1 - 0.012 16.1 0.0 0.02 15.3 0.0 1.4 1 0 0 1 1 1 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_C PF13378.1 EGC28876.1 - 0.087 12.8 0.0 0.11 12.4 0.0 1.2 1 0 0 1 1 1 0 Enolase C-terminal domain-like Coiled PF05710.7 EGC28877.1 - 0.016 15.6 16.6 0.021 15.2 11.5 1.3 1 0 0 1 1 1 0 Coiled coil HutP PF09021.6 EGC28877.1 - 0.022 14.9 1.1 0.024 14.8 0.7 1.1 1 0 0 1 1 1 0 HutP Nipped-B_C PF12830.2 EGC28878.1 - 6.8e-43 146.4 1.1 6.8e-43 146.4 0.8 4.9 5 0 0 5 5 5 1 Sister chromatid cohesion C-terminus Cohesin_HEAT PF12765.2 EGC28878.1 - 2.9e-11 43.0 1.5 3.8e-10 39.5 0.1 3.2 2 0 0 2 2 2 1 HEAT repeat associated with sister chromatid cohesion HEAT_2 PF13646.1 EGC28878.1 - 2.6e-06 27.5 0.0 0.098 12.9 0.0 4.2 3 1 1 4 4 4 3 HEAT repeats HEAT PF02985.17 EGC28878.1 - 1.1e-05 25.1 0.2 24 5.3 0.0 6.8 7 0 0 7 7 7 1 HEAT repeat PHD PF00628.24 EGC28878.1 - 3.6 7.3 15.0 39 4.0 10.4 2.4 1 1 0 1 1 1 0 PHD-finger EF-hand_7 PF13499.1 EGC28880.1 - 1.6e-10 40.9 14.9 1e-05 25.5 0.6 3.2 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC28880.1 - 5.5e-08 32.0 5.6 0.0011 18.6 0.2 4.5 5 1 0 5 5 5 2 EF-hand domain EF-hand_1 PF00036.27 EGC28880.1 - 2.1e-06 26.5 17.3 6.7e-06 25.0 0.2 5.5 6 1 0 6 6 6 1 EF hand EF-hand_8 PF13833.1 EGC28880.1 - 2.2e-06 27.1 13.3 0.00019 20.9 3.5 4.5 4 2 0 4 4 4 2 EF-hand domain pair EF-hand_4 PF12763.2 EGC28880.1 - 0.00038 20.1 1.0 0.13 12.0 0.1 2.5 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand EF-hand_5 PF13202.1 EGC28880.1 - 0.019 14.2 0.6 0.019 14.2 0.4 4.0 4 0 0 4 4 4 0 EF hand EF-hand_9 PF14658.1 EGC28880.1 - 0.042 13.7 0.1 0.39 10.6 0.0 2.7 3 2 0 3 3 3 0 EF-hand domain SinI PF08671.5 EGC28880.1 - 2 7.8 5.3 6.9 6.1 0.2 3.3 3 0 0 3 3 3 0 Anti-repressor SinI CMS1 PF14617.1 EGC28881.1 - 0.18 10.8 3.1 0.17 10.9 2.1 1.1 1 0 0 1 1 1 0 U3-containing 90S pre-ribosomal complex subunit Casc1 PF12366.3 EGC28881.1 - 0.2 11.1 4.0 0.27 10.7 2.8 1.2 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 FAM176 PF14851.1 EGC28881.1 - 0.28 10.8 1.5 0.3 10.7 1.0 1.1 1 0 0 1 1 1 0 FAM176 family Gti1_Pac2 PF09729.4 EGC28881.1 - 0.29 10.9 2.7 0.33 10.7 1.9 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family Peptidase_S49_N PF08496.5 EGC28881.1 - 1.3 8.8 6.9 1.6 8.4 4.8 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF3987 PF13148.1 EGC28881.1 - 2.6 6.5 6.4 2.9 6.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF4175 PF13779.1 EGC28881.1 - 7.1 4.1 8.8 7.7 4.0 6.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAR PF03114.13 EGC28883.1 - 1.4e-17 63.9 11.0 2e-17 63.4 7.6 1.2 1 0 0 1 1 1 1 BAR domain SH3_1 PF00018.23 EGC28883.1 - 2.6e-14 52.3 0.0 4.5e-14 51.5 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC28883.1 - 2.9e-14 52.3 0.0 4.8e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC28883.1 - 2.8e-11 42.7 0.0 4.5e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SATase_N PF06426.9 EGC28883.1 - 0.042 14.1 0.3 0.85 9.9 0.0 2.3 2 0 0 2 2 2 0 Serine acetyltransferase, N-terminal Vps5 PF09325.5 EGC28883.1 - 0.077 12.2 5.6 0.051 12.8 0.6 2.1 2 0 0 2 2 2 0 Vps5 C terminal like PAT1 PF09770.4 EGC28883.1 - 0.3 9.2 14.9 0.43 8.7 10.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4164 PF13747.1 EGC28883.1 - 0.61 10.2 7.3 0.87 9.7 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4164) Rpr2 PF04032.11 EGC28884.1 - 1.9e-06 27.6 7.7 1.9e-06 27.6 5.4 2.6 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 EGC28884.1 - 0.069 12.3 0.9 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGC28884.1 - 0.97 9.3 4.2 9.4 6.1 2.9 2.3 1 1 0 1 1 1 0 Double zinc ribbon ERM PF00769.14 EGC28885.1 - 0.00013 21.6 13.8 0.00013 21.6 9.6 2.1 1 1 1 2 2 2 1 Ezrin/radixin/moesin family TPR_MLP1_2 PF07926.7 EGC28885.1 - 0.0019 17.9 23.3 0.0019 17.9 16.2 2.1 1 1 1 2 2 2 1 TPR/MLP1/MLP2-like protein SprA-related PF12118.3 EGC28885.1 - 0.0048 16.2 20.0 0.0062 15.8 13.9 1.1 1 0 0 1 1 1 1 SprA-related family IncA PF04156.9 EGC28885.1 - 0.021 14.4 30.9 0.027 14.0 21.4 1.1 1 0 0 1 1 1 0 IncA protein CCDC155 PF14662.1 EGC28885.1 - 0.026 14.1 34.1 0.035 13.7 23.7 1.1 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 APG6 PF04111.7 EGC28885.1 - 0.33 9.9 33.8 0.5 9.3 23.4 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Mnd1 PF03962.10 EGC28885.1 - 1.4 8.5 31.7 0.58 9.7 19.1 1.9 1 1 1 2 2 2 0 Mnd1 family Peptidase_S46 PF10459.4 EGC28885.1 - 1.6 7.0 18.3 1.7 6.9 12.7 1.0 1 0 0 1 1 1 0 Peptidase S46 DUF793 PF05633.6 EGC28885.1 - 1.7 7.2 10.4 2.2 6.9 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF793) Laminin_II PF06009.7 EGC28885.1 - 2 8.1 32.7 5.2 6.8 4.1 2.9 1 1 2 3 3 3 0 Laminin Domain II Seryl_tRNA_N PF02403.17 EGC28885.1 - 2.5 8.1 34.1 11 6.0 7.7 2.4 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF972 PF06156.8 EGC28885.1 - 2.7 8.3 30.7 0.1 12.9 11.6 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) Reo_sigmaC PF04582.7 EGC28885.1 - 3.1 6.9 6.2 3.9 6.5 4.3 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein TBPIP PF07106.8 EGC28885.1 - 3.2 7.2 36.6 3.3 7.2 8.2 2.3 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) SpecificRecomb PF10136.4 EGC28885.1 - 4.9 5.0 8.8 6 4.7 6.1 1.0 1 0 0 1 1 1 0 Site-specific recombinase bZIP_1 PF00170.16 EGC28885.1 - 7.1 6.6 32.4 5.4 7.0 3.8 3.5 1 1 2 3 3 3 0 bZIP transcription factor EGF_2 PF07974.8 EGC28886.1 - 0.25 11.5 9.9 0.48 10.6 6.9 1.5 1 0 0 1 1 1 0 EGF-like domain Ras PF00071.17 EGC28887.1 - 3.5e-58 195.5 0.1 4e-58 195.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28887.1 - 4e-21 75.7 0.0 5.5e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC28887.1 - 1.3e-09 37.5 0.0 1.6e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC28887.1 - 2.5e-07 30.3 0.2 8.7e-07 28.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC28887.1 - 3.1e-05 23.9 0.0 5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC28887.1 - 0.00024 19.9 0.3 0.21 10.2 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit Arch_ATPase PF01637.13 EGC28887.1 - 0.16 11.6 0.5 0.61 9.7 0.4 1.9 1 1 0 1 1 1 0 Archaeal ATPase AAA_25 PF13481.1 EGC28887.1 - 0.18 11.2 0.2 0.62 9.4 0.2 2.0 1 1 0 1 1 1 0 AAA domain Ric8 PF10165.4 EGC28888.1 - 6.4e-27 94.4 0.0 5.3e-26 91.4 0.0 1.9 1 1 0 1 1 1 1 Guanine nucleotide exchange factor synembryn SNARE_assoc PF09335.6 EGC28889.1 - 4.1e-14 52.8 0.6 4.1e-14 52.8 0.4 2.1 3 0 0 3 3 3 1 SNARE associated Golgi protein TRP PF06011.7 EGC28889.1 - 0.33 9.4 14.5 0.075 11.5 7.1 2.1 1 1 1 2 2 2 0 Transient receptor potential (TRP) ion channel Vma12 PF11712.3 EGC28889.1 - 0.73 9.5 16.1 0.013 15.2 3.0 3.3 4 1 0 4 4 4 0 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF3753 PF12575.3 EGC28889.1 - 3.2 7.6 16.9 0.37 10.5 1.6 3.7 3 1 0 3 3 3 0 Protein of unknown function (DUF3753) DUF4064 PF13273.1 EGC28889.1 - 3.9 7.6 11.6 1.3 9.1 0.2 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF1083 PF06452.6 EGC28890.1 - 0.0046 16.8 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1083) Beta_helix PF13229.1 EGC28890.1 - 0.016 15.0 4.7 0.022 14.5 3.2 1.3 1 0 0 1 1 1 0 Right handed beta helix region DUF950 PF06106.6 EGC28890.1 - 0.12 12.4 0.3 0.19 11.7 0.2 1.3 1 0 0 1 1 1 0 Staphylococcus protein of unknown function (DUF950) DUF1639 PF07797.9 EGC28893.1 - 5.1 6.5 6.6 37 3.8 4.2 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF1639) Mito_carr PF00153.22 EGC28894.1 - 2.8e-70 232.0 2.5 3.3e-24 84.3 0.0 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein GMC_oxred_N PF00732.14 EGC28895.1 - 4.8e-41 140.8 0.8 7.3e-41 140.2 0.2 1.5 2 0 0 2 2 2 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGC28895.1 - 7.1e-21 75.0 0.1 1.5e-19 70.7 0.0 2.3 2 0 0 2 2 2 1 GMC oxidoreductase DAO PF01266.19 EGC28895.1 - 1.2e-09 37.5 0.2 0.00022 20.2 0.1 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGC28895.1 - 2.2e-08 33.3 1.3 1.2e-07 30.9 0.9 1.9 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGC28895.1 - 1.8e-05 24.6 0.2 5.3e-05 23.1 0.1 1.9 2 0 0 2 2 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGC28895.1 - 0.00011 22.1 0.1 0.00068 19.5 0.1 2.0 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGC28895.1 - 0.00025 20.2 0.3 0.00059 18.9 0.2 1.5 1 0 0 1 1 1 1 Thi4 family FAD_binding_3 PF01494.14 EGC28895.1 - 0.0011 18.0 0.8 0.0017 17.4 0.5 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGC28895.1 - 0.0072 14.8 1.3 0.015 13.8 0.9 1.5 1 0 0 1 1 1 1 HI0933-like protein Lycopene_cycl PF05834.7 EGC28895.1 - 0.0084 15.0 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Lycopene cyclase protein ApbA PF02558.11 EGC28895.1 - 0.032 13.6 0.3 0.062 12.7 0.2 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GDI PF00996.13 EGC28895.1 - 0.064 11.5 1.0 0.085 11.1 0.1 1.5 2 0 0 2 2 2 0 GDP dissociation inhibitor Pyr_redox PF00070.22 EGC28895.1 - 0.17 12.2 0.5 1.2 9.5 0.4 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGC28895.1 - 0.25 11.0 0.9 0.73 9.4 0.5 1.8 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain OrfB_Zn_ribbon PF07282.6 EGC28896.1 - 0.0034 16.9 1.2 0.0095 15.5 0.8 1.7 1 0 0 1 1 1 1 Putative transposase DNA-binding domain Zn_Tnp_IS1595 PF12760.2 EGC28896.1 - 0.037 13.8 0.4 0.08 12.7 0.3 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGC28896.1 - 0.4 10.4 2.7 8 6.2 0.0 3.0 3 0 0 3 3 3 0 zinc-ribbon domain EGF_2 PF07974.8 EGC28897.1 - 9.2e-09 35.3 47.7 0.00025 21.1 6.5 3.7 2 1 1 3 3 3 3 EGF-like domain Cna_B PF05738.8 EGC28897.1 - 0.1 12.3 7.8 0.95 9.2 0.2 3.3 3 0 0 3 3 3 0 Cna protein B-type domain Laminin_EGF PF00053.19 EGC28897.1 - 0.3 11.0 42.8 0.31 10.9 7.0 3.6 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) CBM49 PF09478.5 EGC28898.1 - 2.8e-16 59.3 0.1 4.2e-16 58.8 0.0 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC28898.1 - 0.019 14.9 0.2 0.039 13.8 0.1 1.5 1 0 0 1 1 1 0 DIM protein CBM_2 PF00553.14 EGC28898.1 - 0.079 13.0 0.1 0.11 12.5 0.0 1.2 1 0 0 1 1 1 0 Cellulose binding domain Lysis_col PF02402.11 EGC28899.1 - 0.059 12.9 0.1 0.13 11.8 0.1 1.6 1 0 0 1 1 1 0 Lysis protein LPAM_1 PF08139.7 EGC28899.1 - 0.17 12.1 1.6 0.32 11.2 1.1 1.4 1 0 0 1 1 1 0 Prokaryotic membrane lipoprotein lipid attachment site CAF1A PF12253.3 EGC28900.1 - 5e-16 58.5 25.6 5e-16 58.5 17.7 5.6 3 2 0 3 3 3 1 Chromatin assembly factor 1 subunit A CAF-1_p150 PF11600.3 EGC28900.1 - 1.7e-07 30.8 78.7 1.7e-07 30.8 54.6 4.0 3 1 1 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal ADK PF00406.17 EGC28901.1 - 4.1e-11 42.9 1.0 2.3e-10 40.5 0.7 2.4 1 1 0 1 1 1 1 Adenylate kinase eIF3_p135 PF12807.2 EGC28901.1 - 0.0041 17.0 2.8 0.0093 15.9 0.2 2.2 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 FNIP PF05725.7 EGC28903.1 - 1.5e-33 114.4 49.1 2.6e-08 33.6 0.2 9.5 5 2 7 13 13 13 11 FNIP Repeat LRR_8 PF13855.1 EGC28903.1 - 0.24 11.1 20.6 0.098 12.4 1.3 6.0 6 1 0 6 6 6 0 Leucine rich repeat Baculo_LEF-10 PF07206.6 EGC28903.1 - 0.36 10.4 6.1 0.73 9.5 4.2 1.4 1 0 0 1 1 1 0 Baculovirus late expression factor 10 (LEF-10) LRR_4 PF12799.2 EGC28903.1 - 2 8.1 21.4 2.5 7.8 1.5 6.3 4 2 2 6 6 6 0 Leucine Rich repeats (2 copies) Aldedh PF00171.17 EGC28904.1 - 5.1e-132 440.4 0.3 5.8e-132 440.2 0.2 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Nucleoplasmin PF03066.10 EGC28905.1 - 0.19 11.2 3.9 4.2 6.8 0.8 2.5 2 0 0 2 2 2 0 Nucleoplasmin SDA1 PF05285.7 EGC28905.1 - 1.9 7.6 22.0 0.13 11.5 0.2 2.2 2 0 0 2 2 2 0 SDA1 Pkinase_Tyr PF07714.12 EGC28906.1 - 1.3e-21 76.8 0.0 1.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC28906.1 - 1.1e-14 54.2 0.0 1.5e-14 53.8 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC28906.1 - 0.11 11.3 0.0 0.15 10.9 0.0 1.2 1 0 0 1 1 1 0 Kinase-like AAA_13 PF13166.1 EGC28907.1 - 3.2e-05 22.6 16.0 3.2e-05 22.6 11.1 3.5 1 1 0 2 2 2 1 AAA domain SlyX PF04102.7 EGC28907.1 - 0.0067 16.7 1.4 0.0067 16.7 1.0 6.1 3 2 4 7 7 7 1 SlyX Cep57_CLD_2 PF14197.1 EGC28907.1 - 0.025 14.4 0.8 0.025 14.4 0.5 5.6 5 1 1 6 6 6 0 Centrosome localisation domain of PPC89 Tmp39 PF10271.4 EGC28907.1 - 0.53 8.8 2.4 0.38 9.3 0.5 1.5 2 0 0 2 2 2 0 Putative transmembrane protein DUF604 PF04646.7 EGC28907.1 - 0.61 9.2 2.7 1.5 8.0 1.9 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF604 Baculo_PEP_C PF04513.7 EGC28907.1 - 7.5 6.3 23.3 0.13 12.0 0.7 4.8 1 1 2 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Filament PF00038.16 EGC28907.1 - 7.7 5.8 63.9 77 2.6 1.3 4.0 1 1 2 3 3 3 0 Intermediate filament protein E1-E2_ATPase PF00122.15 EGC28908.1 - 6.2e-25 87.5 3.4 6.8e-23 80.9 0.0 2.7 2 1 1 3 3 3 2 E1-E2 ATPase HAD PF12710.2 EGC28908.1 - 3e-16 60.1 0.0 5.9e-16 59.2 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC28908.1 - 2e-12 48.0 0.0 1.4e-11 45.2 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC28908.1 - 2.8e-07 30.3 0.0 7.5e-07 29.0 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGC28908.1 - 0.0083 15.7 0.4 0.034 13.7 0.0 2.2 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase RRM_6 PF14259.1 EGC28909.1 - 3.8e-13 49.1 0.2 6.7e-13 48.4 0.2 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC28909.1 - 5e-13 48.4 0.9 1.2e-12 47.3 0.6 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC28909.1 - 6.1e-10 38.7 0.5 1.3e-09 37.8 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC28909.1 - 0.058 13.1 0.0 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 Limkain b1 G8 PF10162.4 EGC28910.1 - 4.6e-29 100.7 2.3 7.6e-29 100.0 0.1 2.6 3 0 0 3 3 3 1 G8 domain T4_deiodinase PF00837.12 EGC28911.1 - 4e-22 78.3 0.0 5.4e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Iodothyronine deiodinase Trypan_PARP PF05887.6 EGC28912.1 - 0.088 12.6 8.0 0.095 12.5 5.6 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pex14_N PF04695.8 EGC28912.1 - 2.5 8.1 5.7 2.7 8.0 4.0 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neisseria_TspB PF05616.8 EGC28912.1 - 6.3 5.0 12.9 6.4 5.0 9.0 1.0 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Minor_capsid_2 PF11114.3 EGC28913.1 - 0.18 11.7 2.0 7.5 6.4 0.4 2.2 1 1 1 2 2 2 0 Minor capsid protein OTU PF02338.14 EGC28914.1 - 1.8e-12 47.9 2.3 1.9e-12 47.8 0.0 2.2 2 1 1 3 3 3 1 OTU-like cysteine protease PA14 PF07691.7 EGC28915.1 - 1.4e-08 34.4 0.4 2.4e-08 33.7 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Ste5 PF11610.3 EGC28915.1 - 0.092 12.2 0.1 0.23 11.0 0.1 1.7 1 0 0 1 1 1 0 Scaffold protein Ste5-Fus5 binding region HNH_3 PF13392.1 EGC28916.1 - 8e-11 41.1 2.7 1.7e-10 40.0 1.9 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-CCHC_5 PF14787.1 EGC28916.1 - 3e-07 29.8 0.5 1.7e-06 27.3 0.2 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGC28916.1 - 0.00052 19.8 1.9 0.00086 19.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC28916.1 - 0.014 15.0 0.6 0.031 13.9 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle HNH PF01844.18 EGC28916.1 - 6.9 6.6 8.1 0.49 10.2 1.5 2.0 2 0 0 2 2 2 0 HNH endonuclease Pox_H7 PF04787.7 EGC28917.1 - 0.13 12.0 1.1 0.18 11.6 0.1 1.7 2 0 0 2 2 2 0 Late protein H7 I_LWEQ PF01608.12 EGC28919.1 - 2.9e-05 24.0 8.6 0.0059 16.5 0.8 3.6 2 1 1 3 3 3 3 I/LWEQ domain DDE_3 PF13358.1 EGC28920.1 - 0.0029 17.3 0.0 0.0031 17.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WCCH PF03716.9 EGC28920.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif G-alpha PF00503.15 EGC28923.1 - 7.2e-102 340.9 13.5 9.2e-102 340.6 9.3 1.1 1 0 0 1 1 1 1 G-protein alpha subunit PH PF00169.24 EGC28923.1 - 3.6e-11 43.1 0.0 1.6e-10 41.1 0.0 2.1 1 0 0 1 1 1 1 PH domain Arf PF00025.16 EGC28923.1 - 4.8e-11 42.2 1.4 2.7e-08 33.2 0.1 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family PH_8 PF15409.1 EGC28923.1 - 0.00036 20.5 0.3 0.002 18.1 0.2 2.3 1 1 0 1 1 1 1 Pleckstrin homology domain Gtr1_RagA PF04670.7 EGC28923.1 - 0.0012 18.0 5.6 0.009 15.1 0.1 3.0 2 1 1 3 3 3 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC28923.1 - 0.041 14.3 2.6 3.3 8.2 0.1 3.5 2 2 1 3 3 3 0 Miro-like protein GTP_EFTU PF00009.22 EGC28923.1 - 0.041 13.3 0.5 2.7 7.3 0.0 3.0 2 1 1 3 3 3 0 Elongation factor Tu GTP binding domain Syntaxin-6_N PF09177.6 EGC28923.1 - 0.096 13.0 1.7 9.5 6.7 0.2 2.6 2 0 0 2 2 2 0 Syntaxin 6, N-terminal PH_11 PF15413.1 EGC28923.1 - 0.1 12.8 11.2 0.28 11.4 2.4 3.6 2 1 0 2 2 2 0 Pleckstrin homology domain FRG1 PF06229.7 EGC28923.1 - 0.11 11.9 2.8 0.17 11.3 0.3 2.0 2 0 0 2 2 2 0 FRG1-like family PPTA PF01239.17 EGC28924.1 - 2.2e-20 71.0 20.9 9.2e-07 27.9 0.9 7.1 7 0 0 7 7 7 5 Protein prenyltransferase alpha subunit repeat UVR PF02151.14 EGC28925.1 - 1.5e-05 24.3 3.3 1.5e-05 24.3 2.3 4.9 7 0 0 7 7 7 1 UvrB/uvrC motif Dimer_Tnp_hAT PF05699.9 EGC28927.1 - 1.3e-15 56.8 1.2 2.3e-15 56.0 0.3 1.9 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region DUF4413 PF14372.1 EGC28927.1 - 0.058 13.3 7.6 0.038 13.9 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4413) Talin_middle PF09141.5 EGC28928.1 - 0.096 12.3 0.1 0.18 11.4 0.1 1.5 1 1 0 1 1 1 0 Talin, middle domain RED_N PF07808.8 EGC28932.1 - 2.3e-06 26.9 3.2 2.6e-06 26.8 0.1 2.0 1 1 1 2 2 2 1 RED-like protein N-terminal region DUF4198 PF10670.4 EGC28932.1 - 0.035 14.0 0.2 0.042 13.8 0.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4198) DUF2200 PF09966.4 EGC28933.1 - 0.054 13.3 0.0 0.26 11.1 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) MIF4G_like PF09088.6 EGC28933.1 - 0.081 12.3 0.0 0.13 11.6 0.0 1.3 1 0 0 1 1 1 0 MIF4G like DUF3567 PF12091.3 EGC28933.1 - 0.084 12.8 1.0 40 4.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) Histone PF00125.19 EGC28934.1 - 1.7e-31 108.1 0.9 2.5e-31 107.6 0.6 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC28934.1 - 0.00017 21.7 0.1 0.00026 21.1 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGC28934.1 - 0.014 14.6 0.2 0.014 14.6 0.1 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGC28934.1 - 0.057 13.2 0.1 0.085 12.6 0.0 1.3 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit HisKA PF00512.20 EGC28934.1 - 0.061 13.3 0.3 0.12 12.3 0.2 1.6 1 1 0 1 1 1 0 His Kinase A (phospho-acceptor) domain INTS2 PF14750.1 EGC28935.1 - 2.1e-147 492.4 38.7 1.2e-136 456.8 19.6 2.1 1 1 1 2 2 2 2 Integrator complex subunit 2 CBM49 PF09478.5 EGC28936.1 - 1.3e-21 76.5 1.5 1.3e-21 76.5 1.0 1.7 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 YjgP_YjgQ PF03739.9 EGC28936.1 - 0.0042 15.8 0.2 0.0045 15.7 0.2 1.1 1 0 0 1 1 1 1 Predicted permease YjgP/YjgQ family DUF3530 PF12048.3 EGC28936.1 - 0.0055 15.7 3.8 0.007 15.3 2.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3530) Serinc PF03348.10 EGC28936.1 - 0.015 14.0 1.2 0.017 13.8 0.8 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2946 PF11162.3 EGC28936.1 - 0.044 13.9 0.1 0.052 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) Bap31 PF05529.7 EGC28936.1 - 0.049 13.0 0.2 0.068 12.6 0.1 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like EPL1 PF10513.4 EGC28936.1 - 0.054 13.7 1.0 0.068 13.4 0.7 1.1 1 0 0 1 1 1 0 Enhancer of polycomb-like Tub PF01167.13 EGC28936.1 - 0.06 12.3 1.1 0.076 11.9 0.8 1.2 1 0 0 1 1 1 0 Tub family BAF1_ABF1 PF04684.8 EGC28936.1 - 0.49 9.1 9.3 0.57 8.9 6.5 1.1 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Aminotran_1_2 PF00155.16 EGC28937.1 - 1.3e-14 53.9 0.0 1.6e-14 53.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Ras PF00071.17 EGC28938.1 - 5.8e-53 178.5 0.0 7.7e-53 178.1 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC28938.1 - 1.9e-19 70.2 0.2 3.7e-19 69.3 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC28938.1 - 5.7e-07 28.9 0.0 7.3e-07 28.5 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC28938.1 - 2.3e-05 23.6 0.1 3.1e-05 23.2 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC28938.1 - 0.00069 19.0 0.1 0.0021 17.5 0.0 1.7 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC28938.1 - 0.0091 15.9 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC28938.1 - 0.01 14.5 5.8 0.41 9.2 0.0 3.0 1 1 2 3 3 3 2 G-protein alpha subunit ATP_bind_1 PF03029.12 EGC28938.1 - 0.031 13.8 2.8 0.12 11.8 1.9 1.8 1 1 0 1 1 1 0 Conserved hypothetical ATP binding protein FAM75 PF14650.1 EGC28938.1 - 0.079 12.3 0.4 0.099 12.0 0.3 1.0 1 0 0 1 1 1 0 FAM75 family NB-ARC PF00931.17 EGC28938.1 - 0.3 9.8 4.5 0.59 8.9 0.1 2.2 1 1 1 2 2 2 0 NB-ARC domain UCH PF00443.24 EGC28939.1 - 1.7e-18 66.6 19.9 3.9e-18 65.5 13.8 1.8 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Menin PF05053.8 EGC28939.1 - 0.012 13.7 9.4 0.018 13.2 6.5 1.2 1 0 0 1 1 1 0 Menin TT_ORF1 PF02956.9 EGC28939.1 - 0.5 8.7 15.9 0.67 8.3 11.0 1.3 1 0 0 1 1 1 0 TT viral orf 1 DUF605 PF04652.11 EGC28939.1 - 1.6 8.0 19.6 2 7.7 13.6 1.1 1 0 0 1 1 1 0 Vta1 like OTU PF02338.14 EGC28943.1 - 1.5e-12 48.1 4.8 5.5e-12 46.3 0.1 2.6 2 0 0 2 2 2 1 OTU-like cysteine protease Shisa PF13908.1 EGC28943.1 - 0.0026 17.9 2.8 0.0026 17.9 1.9 2.2 2 1 0 2 2 2 1 Wnt and FGF inhibitory regulator Pex14_N PF04695.8 EGC28943.1 - 0.0061 16.6 2.4 0.0061 16.6 1.6 2.6 2 1 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF1980 PF09323.5 EGC28943.1 - 0.0093 15.7 0.9 0.0093 15.7 0.6 2.4 2 1 1 3 3 3 1 Domain of unknown function (DUF1980) Gti1_Pac2 PF09729.4 EGC28943.1 - 4.6 7.0 10.8 0.13 12.1 0.5 2.2 2 0 0 2 2 2 0 Gti1/Pac2 family DUF4407 PF14362.1 EGC28943.1 - 8 5.3 8.6 14 4.5 5.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) SRF-TF PF00319.13 EGC28944.1 - 2.1e-15 55.6 0.1 4.9e-15 54.4 0.0 1.6 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) HbrB PF08539.6 EGC28945.1 - 0.26 11.1 3.4 0.97 9.2 0.0 2.8 3 1 0 3 3 3 0 HbrB-like adh_short PF00106.20 EGC28946.1 - 2.1e-25 89.5 0.0 5.2e-25 88.2 0.0 1.6 1 1 1 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGC28946.1 - 2.9e-13 49.8 0.0 4.1e-13 49.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC28946.1 - 1e-09 38.5 0.0 1.4e-09 38.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGC28946.1 - 5.3e-07 29.3 0.0 7.8e-07 28.7 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGC28946.1 - 0.00011 21.4 0.1 0.00019 20.7 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC28946.1 - 0.00034 20.6 0.0 0.00064 19.7 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGC28946.1 - 0.0022 16.9 0.1 0.003 16.4 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein AA_kinase PF00696.23 EGC28946.1 - 0.0088 15.6 0.0 0.0098 15.4 0.0 1.4 1 1 0 1 1 1 1 Amino acid kinase family BDV_P24 PF06595.6 EGC28946.1 - 0.022 14.5 0.4 0.031 14.0 0.3 1.2 1 0 0 1 1 1 0 Borna disease virus P24 protein Gag_p17 PF00540.13 EGC28946.1 - 0.036 13.8 0.1 0.055 13.2 0.1 1.3 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) Pox_A21 PF05323.7 EGC28946.1 - 0.057 13.8 2.5 0.074 13.4 0.6 2.0 2 0 0 2 2 2 0 Poxvirus A21 Protein Eno-Rase_NADH_b PF12242.3 EGC28946.1 - 0.072 12.8 0.2 0.16 11.7 0.1 1.6 1 1 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase ABC_tran PF00005.22 EGC28947.1 - 6.1e-34 117.2 0.0 1.3e-20 74.0 0.0 2.8 3 0 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGC28947.1 - 5.5e-20 70.9 3.4 5.5e-20 70.9 2.4 1.7 2 0 0 2 2 1 1 ABC transporter AAA_21 PF13304.1 EGC28947.1 - 2.2e-14 54.1 0.7 0.003 17.5 0.0 3.4 2 1 0 3 3 3 3 AAA domain AAA_29 PF13555.1 EGC28947.1 - 1.4e-08 34.1 0.0 0.0011 18.3 0.0 2.4 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGC28947.1 - 1.9e-07 30.5 0.3 0.0063 15.7 0.0 3.7 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGC28947.1 - 2.5e-07 31.2 7.7 0.076 13.3 0.0 4.2 4 0 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EGC28947.1 - 2.1e-06 28.5 0.0 0.1 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGC28947.1 - 2.7e-06 26.6 0.0 0.0045 16.1 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC28947.1 - 3.9e-06 27.0 0.0 0.044 13.9 0.0 2.8 3 0 0 3 3 2 2 AAA domain Miro PF08477.8 EGC28947.1 - 6e-06 26.7 0.0 0.21 12.0 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein NACHT PF05729.7 EGC28947.1 - 7.6e-06 25.6 0.4 0.025 14.2 0.0 3.0 2 1 0 2 2 2 2 NACHT domain AAA_16 PF13191.1 EGC28947.1 - 1.5e-05 25.0 0.0 0.029 14.3 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain MMR_HSR1 PF01926.18 EGC28947.1 - 3.4e-05 23.7 0.0 0.045 13.7 0.2 3.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase RNA_helicase PF00910.17 EGC28947.1 - 4.5e-05 23.5 0.1 0.086 13.0 0.0 2.9 3 0 0 3 3 2 1 RNA helicase MobB PF03205.9 EGC28947.1 - 0.00012 21.7 0.1 0.0041 16.8 0.1 2.6 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGC28947.1 - 0.00016 21.1 2.5 0.014 14.9 0.0 3.1 3 1 0 3 3 3 1 AAA-like domain AAA_14 PF13173.1 EGC28947.1 - 0.00021 21.2 0.0 0.33 10.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EGC28947.1 - 0.00029 20.7 0.0 0.42 10.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA PF00004.24 EGC28947.1 - 0.00075 19.7 0.0 0.15 12.2 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGC28947.1 - 0.00083 19.1 1.5 0.26 10.9 0.0 3.0 3 0 0 3 3 3 1 Archaeal ATPase NB-ARC PF00931.17 EGC28947.1 - 0.001 17.9 0.0 0.32 9.8 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain AAA_25 PF13481.1 EGC28947.1 - 0.0014 18.1 0.0 0.85 8.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC28947.1 - 0.0038 17.5 0.2 0.72 10.1 0.0 2.9 3 0 0 3 3 2 1 AAA domain PduV-EutP PF10662.4 EGC28947.1 - 0.004 16.6 0.1 3.4 7.1 0.0 3.2 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation AAA_5 PF07728.9 EGC28947.1 - 0.0045 16.7 0.8 0.69 9.6 0.0 2.7 3 0 0 3 3 2 1 AAA domain (dynein-related subfamily) G-alpha PF00503.15 EGC28947.1 - 0.005 15.5 0.6 2.2 6.8 0.5 2.8 2 1 0 2 2 2 1 G-protein alpha subunit Septin PF00735.13 EGC28947.1 - 0.01 14.8 0.0 2.4 7.0 0.0 2.4 2 0 0 2 2 2 0 Septin AAA_28 PF13521.1 EGC28947.1 - 0.013 15.5 0.0 1.3 8.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGC28947.1 - 0.013 15.3 2.6 0.45 10.3 0.0 3.3 3 1 1 4 4 4 0 Domain of unknown function DUF87 DUF2813 PF11398.3 EGC28947.1 - 0.015 14.3 0.1 5.4 6.0 0.0 2.5 3 0 0 3 3 2 0 Protein of unknown function (DUF2813) Sigma54_activ_2 PF14532.1 EGC28947.1 - 0.022 14.8 0.0 0.34 10.9 0.0 2.4 2 0 0 2 2 2 0 Sigma-54 interaction domain VirE PF05272.6 EGC28947.1 - 0.025 14.0 0.1 9.5 5.6 0.0 3.1 3 0 0 3 3 3 0 Virulence-associated protein E ArgK PF03308.11 EGC28947.1 - 0.028 13.2 0.0 4.5 5.9 0.0 2.5 2 0 0 2 2 2 0 ArgK protein NTPase_1 PF03266.10 EGC28947.1 - 0.032 13.9 0.1 0.67 9.6 0.1 2.6 2 0 0 2 2 2 0 NTPase AAA_13 PF13166.1 EGC28947.1 - 0.038 12.4 4.2 2.4 6.5 0.1 3.2 3 1 0 3 3 3 0 AAA domain FeoB_N PF02421.13 EGC28947.1 - 0.038 13.2 0.0 9.5 5.4 0.0 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.8 EGC28947.1 - 0.046 12.6 0.1 1.3 7.8 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF815) DAP3 PF10236.4 EGC28947.1 - 0.053 12.4 0.3 3.1 6.6 0.0 2.6 3 0 0 3 3 3 0 Mitochondrial ribosomal death-associated protein 3 Dynamin_N PF00350.18 EGC28947.1 - 0.083 12.7 0.7 15 5.4 0.0 3.1 2 1 1 3 3 3 0 Dynamin family ATP-synt_ab PF00006.20 EGC28947.1 - 0.13 11.6 0.0 7 6.0 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ADP_ribosyl_GH PF03747.9 EGC28948.1 - 4.9e-65 220.1 0.0 5.9e-65 219.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase AAA_34 PF13872.1 EGC28948.1 - 0.12 11.1 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 P-loop containing NTP hydrolase pore-1 Ribosomal_S7 PF00177.16 EGC28948.1 - 0.37 10.3 2.7 0.78 9.3 1.9 1.4 1 0 0 1 1 1 0 Ribosomal protein S7p/S5e DUF1767 PF08585.7 EGC28949.1 - 6.9e-19 67.9 0.2 2.6e-18 66.0 0.1 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1767) DUF605 PF04652.11 EGC28949.1 - 0.026 13.9 19.6 0.034 13.5 13.6 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EGC28949.1 - 0.38 10.5 16.4 0.049 13.5 6.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit LBP_BPI_CETP_C PF02886.12 EGC28950.1 - 3.8e-11 42.6 3.0 7.4e-11 41.7 2.1 1.4 1 0 0 1 1 1 1 LBP / BPI / CETP family, C-terminal domain AMP-binding PF00501.23 EGC28951.1 - 3.3e-76 256.3 0.0 4.1e-76 256.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC28951.1 - 1.6e-07 32.1 0.0 2.8e-07 31.3 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EGC28952.1 - 2.5e-09 36.6 0.2 0.0036 17.1 0.4 5.1 5 0 0 5 5 5 2 WD domain, G-beta repeat Herpes_gI PF01688.12 EGC28952.1 - 0.037 13.1 0.0 0.07 12.2 0.0 1.4 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein I Reg_prop PF07494.6 EGC28952.1 - 0.15 12.2 1.3 27 5.2 0.1 3.7 4 0 0 4 4 4 0 Two component regulator propeller RP-C_C PF11800.3 EGC28952.1 - 0.38 10.4 10.5 0.58 9.8 7.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region MMR1 PF08505.5 EGC28952.1 - 0.83 9.6 11.1 2.1 8.3 7.7 1.6 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein UCH PF00443.24 EGC28953.1 - 4.4e-50 170.2 15.6 4.4e-50 170.2 10.8 2.5 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC28953.1 - 2.7e-24 86.1 15.9 2.7e-24 86.1 11.1 3.5 2 2 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase zf-RING_2 PF13639.1 EGC28954.1 - 2.6e-09 36.7 15.5 5.7e-09 35.6 10.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC28954.1 - 3e-06 27.2 10.6 8.9e-06 25.7 7.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC28954.1 - 4.9e-05 22.9 14.4 9.7e-05 21.9 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC28954.1 - 0.00025 20.6 19.9 0.00025 20.6 13.8 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC28954.1 - 0.00059 19.8 18.2 0.0013 18.7 12.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC28954.1 - 0.018 14.7 17.8 0.018 14.7 12.3 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGC28954.1 - 0.073 12.9 9.2 0.36 10.7 6.4 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC28954.1 - 0.2 11.3 12.1 1.1 8.9 8.4 2.4 1 0 0 1 1 1 0 RING-type zinc-finger DUF393 PF04134.7 EGC28954.1 - 1.4 10.0 0.0 1.4 10.0 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF393 zf-C3HC4_4 PF15227.1 EGC28954.1 - 2.3 8.1 18.3 2.1 8.3 10.7 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING tRNA-synt_1b PF00579.20 EGC28955.1 - 1.2e-62 211.7 0.2 1.6e-62 211.3 0.2 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) Gemini_AL3 PF01407.12 EGC28956.1 - 0.058 12.8 4.3 0.087 12.2 2.3 1.7 1 1 1 2 2 2 0 Geminivirus AL3 protein TEX15 PF15326.1 EGC28956.1 - 0.1 12.2 2.0 0.16 11.5 1.4 1.3 1 0 0 1 1 1 0 Testis expressed sequence 15 TEBP_beta PF07404.6 EGC28956.1 - 0.45 9.5 2.6 0.59 9.2 1.8 1.2 1 0 0 1 1 1 0 Telomere-binding protein beta subunit (TEBP beta) RCC1 PF00415.13 EGC28958.1 - 2.1e-75 248.7 20.3 9.7e-15 54.5 0.1 8.4 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC28958.1 - 3.8e-33 112.3 37.0 9.5e-07 28.2 0.5 8.6 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat Cmyb_C PF09316.5 EGC28958.1 - 0.39 10.3 4.6 0.68 9.5 3.2 1.4 1 0 0 1 1 1 0 C-myb, C-terminal ABC1 PF03109.11 EGC28961.1 - 1.1e-31 109.2 0.1 3.1e-31 107.7 0.1 1.8 1 0 0 1 1 1 1 ABC1 family Pkinase PF00069.20 EGC28962.1 - 1.9e-59 200.9 0.6 1.1e-58 198.5 0.4 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28962.1 - 2e-27 95.8 0.6 2.9e-19 69.1 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGC28962.1 - 8.6e-07 29.3 2.1 2e-06 28.2 1.5 1.7 1 0 0 1 1 1 1 Protein kinase C terminal domain APH PF01636.18 EGC28962.1 - 0.0017 18.1 0.0 0.054 13.2 0.0 2.2 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGC28962.1 - 0.0019 17.2 0.0 0.0066 15.4 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGC28962.1 - 0.007 15.2 0.0 0.016 14.0 0.0 1.5 1 0 0 1 1 1 1 Seadornavirus VP7 DKNYY PF13644.1 EGC28962.1 - 0.39 10.9 3.8 2 8.6 0.1 2.5 2 1 0 2 2 2 0 DKNYY family Myb_DNA-binding PF00249.26 EGC28963.1 - 0.00027 20.9 0.0 0.00071 19.5 0.0 1.8 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC28963.1 - 0.00055 19.9 0.5 0.0031 17.5 0.1 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain LysM PF01476.15 EGC28965.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.6 3 0 0 3 3 3 0 LysM domain Med28 PF11594.3 EGC28966.1 - 0.0022 18.1 9.1 0.0024 18.1 5.7 1.5 1 1 0 1 1 1 1 Mediator complex subunit 28 Atg14 PF10186.4 EGC28966.1 - 0.053 12.4 5.7 0.062 12.2 4.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2935 PF11155.3 EGC28966.1 - 0.18 11.9 5.4 0.33 11.0 3.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) HSP70 PF00012.15 EGC28966.1 - 0.32 8.8 4.1 0.35 8.7 2.8 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF342 PF03961.8 EGC28966.1 - 1.4 7.2 8.2 1.7 7.0 5.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) IncA PF04156.9 EGC28966.1 - 1.5 8.3 9.7 2.4 7.7 6.7 1.3 1 1 0 1 1 1 0 IncA protein adh_short PF00106.20 EGC28967.1 - 9.4e-22 77.6 0.0 1.2e-21 77.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC28967.1 - 1.3e-17 64.3 0.0 1.9e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC28967.1 - 1.1e-05 25.2 0.0 1.5e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC28967.1 - 1.8e-05 24.0 0.1 3.4e-05 23.1 0.1 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC28967.1 - 0.15 12.0 0.0 0.54 10.2 0.0 1.9 2 0 0 2 2 2 0 NADH(P)-binding UNC-50 PF05216.8 EGC28968.1 - 5.6e-84 280.9 26.8 6.5e-84 280.7 18.5 1.0 1 0 0 1 1 1 1 UNC-50 family GCV_T PF01571.16 EGC28969.1 - 3.6e-68 229.0 0.0 4.4e-68 228.7 0.0 1.1 1 0 0 1 1 1 1 Aminomethyltransferase folate-binding domain GCV_T_C PF08669.6 EGC28969.1 - 8e-21 73.8 0.1 1.4e-20 73.1 0.1 1.4 1 0 0 1 1 1 1 Glycine cleavage T-protein C-terminal barrel domain SoxG PF04268.7 EGC28969.1 - 0.0022 17.8 0.0 0.004 17.0 0.0 1.5 1 0 0 1 1 1 1 Sarcosine oxidase, gamma subunit family Myosin_head PF00063.16 EGC28970.1 - 5e-197 656.1 21.3 5e-197 656.1 14.8 2.7 3 1 0 3 3 3 1 Myosin head (motor domain) RhoGEF PF00621.15 EGC28970.1 - 3.8e-56 189.7 1.8 3.8e-56 189.7 1.2 5.1 5 1 0 5 5 5 2 RhoGEF domain PH PF00169.24 EGC28970.1 - 1.2e-05 25.4 1.1 1.2e-05 25.4 0.8 3.7 3 0 0 3 3 3 1 PH domain AAA_22 PF13401.1 EGC28970.1 - 0.018 15.1 0.2 0.13 12.3 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC28970.1 - 0.046 13.7 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 AAA ATPase domain MIP-T3 PF10243.4 EGC28970.1 - 2.5 6.4 57.7 0.017 13.6 31.9 2.5 3 0 0 3 3 3 0 Microtubule-binding protein MIP-T3 DIM1 PF02966.11 EGC28971.1 - 1.4e-65 218.7 0.2 1.6e-65 218.6 0.1 1.0 1 0 0 1 1 1 1 Mitosis protein DIM1 Thioredoxin PF00085.15 EGC28971.1 - 0.00084 18.9 0.1 0.0012 18.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGC28971.1 - 0.0038 17.2 0.1 0.0054 16.8 0.1 1.3 1 0 0 1 1 1 1 Thioredoxin-like DUF3192 PF11399.3 EGC28971.1 - 0.07 13.0 0.0 0.089 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3192) DUF870 PF05912.6 EGC28971.1 - 0.11 12.3 0.1 0.27 11.0 0.1 1.6 2 0 0 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) Clenterotox PF03505.9 EGC28972.1 - 0.047 13.0 0.1 0.08 12.3 0.0 1.4 1 0 0 1 1 1 0 Clostridium enterotoxin DUF2874 PF11396.3 EGC28972.1 - 0.33 10.9 2.6 21 5.1 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF2874) Glyco_hydro_38 PF01074.17 EGC28973.1 - 2.5e-67 227.0 2.3 2.5e-67 227.0 1.6 1.9 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC28973.1 - 5.2e-20 71.4 0.3 5.2e-20 71.4 0.2 2.6 3 0 0 3 3 3 1 Alpha mannosidase, middle domain TMEM154 PF15102.1 EGC28973.1 - 0.0033 17.1 0.2 0.0093 15.6 0.1 1.7 1 0 0 1 1 1 1 TMEM154 protein family DUF4064 PF13273.1 EGC28973.1 - 0.14 12.2 1.4 0.28 11.3 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) OsmC PF02566.14 EGC28974.1 - 1.6e-21 76.3 0.2 2.4e-21 75.8 0.1 1.2 1 0 0 1 1 1 1 OsmC-like protein WD40 PF00400.27 EGC28975.1 - 0.00013 21.7 5.8 0.26 11.2 0.1 4.5 4 0 0 4 4 4 3 WD domain, G-beta repeat Synaptobrevin PF00957.16 EGC28975.1 - 0.019 14.5 0.3 0.019 14.5 0.2 1.8 2 0 0 2 2 2 0 Synaptobrevin FAM176 PF14851.1 EGC28975.1 - 0.079 12.6 5.2 0.028 14.1 1.0 2.1 2 0 0 2 2 2 0 FAM176 family DUF4175 PF13779.1 EGC28976.1 - 0.11 10.1 3.5 0.16 9.6 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF717 PF05338.7 EGC28976.1 - 0.23 11.4 1.8 21 5.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF717) Lectin_legB PF00139.14 EGC28977.1 - 2.8e-21 75.9 2.8 2.8e-21 75.9 1.9 1.6 2 0 0 2 2 2 1 Legume lectin domain Laminin_G_1 PF00054.18 EGC28977.1 - 0.0055 16.7 0.1 0.028 14.4 0.0 2.0 2 0 0 2 2 2 1 Laminin G domain Laminin_G_2 PF02210.19 EGC28977.1 - 0.025 14.6 1.2 0.038 14.0 0.0 1.8 2 0 0 2 2 2 0 Laminin G domain Methyltransf_12 PF08242.7 EGC28977.1 - 4.7 7.7 6.6 55 4.3 3.2 2.6 2 1 0 2 2 2 0 Methyltransferase domain EGF_CA PF07645.10 EGC28978.1 - 2.7e-05 24.0 6.1 2.7e-05 24.0 4.2 5.1 3 1 1 4 4 4 1 Calcium-binding EGF domain FXa_inhibition PF14670.1 EGC28978.1 - 0.00058 19.9 5.7 0.00058 19.9 4.0 5.1 3 1 1 4 4 4 1 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EGC28978.1 - 0.0018 17.8 3.8 0.0018 17.8 2.7 4.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like hEGF PF12661.2 EGC28978.1 - 0.0091 16.0 1.5 0.0091 16.0 1.0 4.4 5 0 0 5 5 5 1 Human growth factor-like EGF Podoplanin PF05808.6 EGC28978.1 - 0.01 15.3 0.3 0.02 14.4 0.2 1.4 1 0 0 1 1 1 0 Podoplanin EGF_2 PF07974.8 EGC28978.1 - 0.011 15.9 15.3 0.011 15.9 10.6 4.9 4 0 0 4 4 4 0 EGF-like domain adh_short PF00106.20 EGC28979.1 - 4.9e-19 68.8 0.0 6.2e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC28979.1 - 1.3e-05 24.9 0.0 1.9e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGC28979.1 - 0.0069 15.3 0.0 0.0093 14.8 0.0 1.1 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein FNIP PF05725.7 EGC28980.1 - 9.6e-93 303.9 57.5 4.2e-16 58.6 1.1 10.4 10 0 0 10 10 10 9 FNIP Repeat OCIA PF07051.6 EGC28980.1 - 0.04 13.3 2.8 5.5 6.4 0.0 2.9 2 0 0 2 2 2 0 Ovarian carcinoma immunoreactive antigen (OCIA) Ufd2P_core PF10408.4 EGC28981.1 - 1.2e-168 562.2 20.0 1.9e-168 561.5 13.9 1.3 1 0 0 1 1 1 1 Ubiquitin elongating factor core U-box PF04564.10 EGC28981.1 - 3.4e-30 103.8 2.8 5.9e-30 103.0 1.0 2.3 2 0 0 2 2 2 1 U-box domain Ras PF00071.17 EGC28982.1 - 1.8e-28 98.9 0.4 3.7e-28 97.9 0.3 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC28982.1 - 1.4e-13 51.3 1.5 3.7e-11 43.5 0.1 2.9 2 2 1 3 3 3 1 Miro-like protein GTP_EFTU PF00009.22 EGC28982.1 - 6.2e-07 29.0 0.3 4.1e-05 23.1 0.2 2.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Arf PF00025.16 EGC28982.1 - 2.7e-05 23.4 0.0 0.00025 20.3 0.0 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC28982.1 - 0.00017 21.5 1.4 0.00033 20.6 0.1 2.0 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC28982.1 - 0.0066 15.7 0.3 0.05 12.8 0.2 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF4463 PF14703.1 EGC28982.1 - 0.18 12.3 1.5 6 7.4 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4463) TIG PF01833.19 EGC28983.1 - 1e-05 25.3 25.4 0.0018 18.2 0.5 3.4 2 2 1 3 3 3 2 IPT/TIG domain EGF_2 PF07974.8 EGC28983.1 - 0.0085 16.2 13.2 0.0085 16.2 9.1 4.2 4 0 0 4 4 4 2 EGF-like domain Laminin_EGF PF00053.19 EGC28983.1 - 0.095 12.6 0.2 0.095 12.6 0.1 3.6 3 1 0 3 3 3 0 Laminin EGF-like (Domains III and V) Oxidored_FMN PF00724.15 EGC28985.1 - 1.4e-07 30.8 0.0 1.4e-07 30.8 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family P16-Arc PF04699.9 EGC28986.1 - 2.2e-38 131.6 0.1 2.7e-38 131.3 0.1 1.0 1 0 0 1 1 1 1 ARP2/3 complex 16 kDa subunit (p16-Arc) UTP15_C PF09384.5 EGC28986.1 - 0.094 12.3 0.0 0.12 12.0 0.0 1.1 1 0 0 1 1 1 0 UTP15 C terminal Nop10p PF04135.7 EGC28987.1 - 4e-17 61.6 0.2 4.6e-17 61.4 0.2 1.0 1 0 0 1 1 1 1 Nucleolar RNA-binding protein, Nop10p family Ins_P5_2-kin PF06090.7 EGC28988.1 - 1.3e-70 237.8 3.3 1.6e-70 237.6 2.3 1.1 1 0 0 1 1 1 1 Inositol-pentakisphosphate 2-kinase Kinesin PF00225.18 EGC28989.1 - 1.2e-102 343.0 0.2 1.2e-102 343.0 0.1 3.6 4 1 0 4 4 4 1 Kinesin motor domain AphA_like PF14557.1 EGC28989.1 - 0.031 13.8 0.0 0.087 12.3 0.0 1.8 1 0 0 1 1 1 0 Putative AphA-like transcriptional regulator AAA_22 PF13401.1 EGC28989.1 - 0.52 10.4 0.0 0.52 10.4 0.0 4.0 3 1 0 3 3 3 0 AAA domain CBS PF00571.23 EGC28990.1 - 1.9e-15 56.3 0.9 0.00017 21.3 0.0 4.4 4 0 0 4 4 4 4 CBS domain Ribosomal_L29 PF00831.18 EGC28991.1 - 4.3e-18 64.7 3.1 9e-18 63.7 0.4 2.1 2 0 0 2 2 2 1 Ribosomal L29 protein DUF2205 PF10224.4 EGC28991.1 - 0.079 12.5 0.4 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) Snapin_Pallidin PF14712.1 EGC28991.1 - 0.082 13.2 2.0 0.08 13.2 0.6 1.6 1 1 1 2 2 2 0 Snapin/Pallidin Ribosomal_S9 PF00380.14 EGC28991.1 - 0.11 12.7 2.8 0.19 12.0 1.9 1.7 1 1 0 1 1 1 0 Ribosomal protein S9/S16 LURAP PF14854.1 EGC28991.1 - 0.12 12.1 0.6 0.23 11.1 0.2 1.6 1 1 0 1 1 1 0 Leucine rich adaptor protein IFP_35_N PF07334.8 EGC28991.1 - 0.13 12.2 0.6 0.24 11.3 0.4 1.6 1 1 0 1 1 1 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus Annexin PF00191.15 EGC28991.1 - 0.14 12.0 0.9 0.23 11.3 0.1 1.7 2 0 0 2 2 2 0 Annexin HrpB7 PF09486.5 EGC28991.1 - 3.2 7.6 7.5 0.64 9.9 1.0 2.4 1 1 2 3 3 3 0 Bacterial type III secretion protein (HrpB7) SIR2 PF02146.12 EGC28992.1 - 1.8e-57 193.9 0.0 3.1e-57 193.1 0.0 1.4 1 0 0 1 1 1 1 Sir2 family DUF164 PF02591.10 EGC28992.1 - 0.0054 16.5 0.6 0.046 13.5 0.3 2.6 3 0 0 3 3 3 1 Putative zinc ribbon domain TPP_enzyme_M PF00205.17 EGC28992.1 - 0.0056 16.4 0.0 3.8 7.2 0.0 2.3 2 0 0 2 2 2 2 Thiamine pyrophosphate enzyme, central domain DUF1272 PF06906.6 EGC28992.1 - 0.068 13.0 0.6 0.14 12.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) CAF-1_p150 PF11600.3 EGC28992.1 - 0.8 9.0 9.6 1.2 8.5 6.7 1.1 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Mucin PF01456.12 EGC28992.1 - 1.2 8.8 23.6 2 8.1 16.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein PP_M1 PF03012.9 EGC28992.1 - 9.2 5.5 12.2 65 2.7 8.4 2.1 1 1 0 1 1 1 0 Phosphoprotein Aminotran_5 PF00266.14 EGC28993.1 - 2.4e-36 125.2 0.0 3.3e-36 124.8 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGC28993.1 - 0.0023 17.1 0.0 0.0048 16.0 0.0 1.6 1 1 0 1 1 1 1 Beta-eliminating lyase Pyridoxal_deC PF00282.14 EGC28993.1 - 0.0063 15.0 0.4 0.072 11.5 0.0 2.5 3 0 0 3 3 3 1 Pyridoxal-dependent decarboxylase conserved domain Cys_Met_Meta_PP PF01053.15 EGC28993.1 - 0.019 13.2 0.0 0.028 12.7 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme PALP PF00291.20 EGC28993.1 - 0.024 13.8 0.0 0.035 13.3 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme DUF2296 PF10058.4 EGC28994.1 - 9.5e-17 60.4 0.1 2e-16 59.4 0.1 1.6 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) LMBR1 PF04791.11 EGC28994.1 - 0.0032 16.1 0.5 0.0032 16.1 0.4 3.1 3 0 0 3 3 3 1 LMBR1-like membrane protein TMF_DNA_bd PF12329.3 EGC28994.1 - 0.0063 16.3 11.6 0.0063 16.3 8.0 6.1 4 2 2 6 6 6 1 TATA element modulatory factor 1 DNA binding Gelsolin PF00626.17 EGC28995.1 - 4e-49 164.1 0.0 1.7e-16 59.6 0.0 3.1 3 0 0 3 3 3 3 Gelsolin repeat UDPGP PF01704.13 EGC28996.1 - 8.4e-173 574.6 6.5 1.2e-172 574.2 4.5 1.2 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase FtsJ PF01728.14 EGC28997.1 - 2.7e-08 34.0 0.0 6.5e-08 32.7 0.0 1.6 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_23 PF13489.1 EGC28997.1 - 0.012 15.2 0.0 0.22 11.2 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Pkinase PF00069.20 EGC28998.1 - 4e-71 239.2 1.3 8e-71 238.2 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC28998.1 - 1.1e-70 237.6 0.1 2.5e-70 236.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Myotub-related PF06602.9 EGC28999.1 - 1.6e-63 214.6 2.7 1.6e-63 214.6 1.9 2.9 2 1 0 2 2 1 1 Myotubularin-like phosphatase domain Pkinase_Tyr PF07714.12 EGC28999.1 - 9.1e-49 165.8 0.0 1.6e-48 165.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC28999.1 - 1.6e-42 145.4 0.0 3.5e-42 144.3 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 EGC28999.1 - 9.3e-25 85.7 85.6 1.2e-07 31.1 4.9 11.1 3 2 7 12 12 12 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC28999.1 - 4.3e-24 84.0 65.6 5.4e-07 29.2 5.2 7.5 3 1 4 7 7 7 6 Leucine rich repeat Miro PF08477.8 EGC28999.1 - 5.9e-14 52.5 0.1 2e-13 50.8 0.1 2.1 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGC28999.1 - 3.8e-13 49.1 0.7 9.1e-13 47.9 0.5 1.6 1 0 0 1 1 1 1 Ras family WD40 PF00400.27 EGC28999.1 - 3.1e-09 36.3 11.4 0.0044 16.8 0.4 5.0 4 0 0 4 4 4 3 WD domain, G-beta repeat LRR_1 PF00560.28 EGC28999.1 - 3.4e-06 26.3 77.3 0.41 10.8 0.9 16.4 15 1 0 15 15 14 4 Leucine Rich Repeat Arf PF00025.16 EGC28999.1 - 3.7e-06 26.2 4.0 1.8e-05 24.0 2.8 2.1 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGC28999.1 - 0.0044 17.1 0.0 3.3 7.8 0.0 3.0 2 0 0 2 2 2 1 AAA domain RA PF00788.18 EGC28999.1 - 0.028 14.9 0.0 0.095 13.2 0.0 1.9 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain AAA_17 PF13207.1 EGC28999.1 - 0.071 13.9 0.0 0.22 12.3 0.0 1.9 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGC28999.1 - 0.1 12.3 0.2 0.4 10.3 0.2 1.9 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PduV-EutP PF10662.4 EGC28999.1 - 0.62 9.5 5.4 0.16 11.4 0.2 2.7 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation APH PF01636.18 EGC28999.1 - 0.69 9.5 0.0 1.2 8.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ank_2 PF12796.2 EGC29000.1 - 2.4e-12 47.0 0.3 1.9e-07 31.3 0.0 3.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC29000.1 - 1.4e-08 34.1 0.6 4.1e-05 23.1 0.0 4.2 4 0 0 4 4 4 1 Ankyrin repeat Ank_3 PF13606.1 EGC29000.1 - 1.4e-07 31.0 0.1 0.044 14.0 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGC29000.1 - 1.3e-06 28.4 0.0 1.3e-06 28.4 0.0 5.4 5 1 0 5 5 5 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC29000.1 - 4.5e-06 27.0 0.1 0.25 11.9 0.0 3.4 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Tmemb_185A PF10269.4 EGC29001.1 - 3.4e-05 23.5 26.1 4.3e-05 23.2 10.9 2.3 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein PHF5 PF03660.9 EGC29002.1 - 1.3e-48 163.4 11.2 1.5e-48 163.3 7.8 1.0 1 0 0 1 1 1 1 PHF5-like protein PolC_DP2 PF03833.8 EGC29002.1 - 0.0084 13.8 2.6 0.0095 13.6 1.8 1.1 1 0 0 1 1 1 1 DNA polymerase II large subunit DP2 PHD PF00628.24 EGC29002.1 - 0.01 15.5 7.8 0.01 15.5 5.4 2.4 2 1 0 2 2 2 1 PHD-finger DZR PF12773.2 EGC29002.1 - 2 8.2 17.5 0.34 10.7 2.6 2.9 1 1 1 2 2 2 0 Double zinc ribbon DnaJ_CXXCXGXG PF00684.14 EGC29002.1 - 4 7.5 17.9 0.95 9.5 3.1 2.6 1 1 1 2 2 2 0 DnaJ central domain Ribosomal_L18e PF00828.14 EGC29003.1 - 1.4e-18 67.5 0.3 2.4e-18 66.7 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Hexapep PF00132.19 EGC29005.1 - 1.1e-11 43.6 3.9 0.014 14.8 0.0 3.5 2 1 1 3 3 3 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGC29005.1 - 7.3e-08 32.0 0.0 1.6e-07 30.8 0.0 1.7 1 1 0 1 1 1 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EGC29005.1 - 0.0031 17.0 3.1 0.59 9.7 1.3 3.1 1 1 2 3 3 3 3 Hexapeptide repeat of succinyl-transferase NTP_transf_3 PF12804.2 EGC29005.1 - 0.035 14.1 0.0 0.047 13.7 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain Cyt-b5 PF00173.23 EGC29006.1 - 1.3e-23 82.5 0.1 1.4e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NUDIX PF00293.23 EGC29007.1 - 1.1e-22 80.1 0.0 1.4e-22 79.8 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGC29007.1 - 0.0015 17.9 0.0 0.005 16.2 0.0 1.7 2 0 0 2 2 2 1 NUDIX domain MIP PF00230.15 EGC29008.1 - 1.2e-26 93.6 9.3 1.6e-26 93.2 6.4 1.2 1 0 0 1 1 1 1 Major intrinsic protein Alpha_kinase PF02816.13 EGC29009.1 - 1.1e-56 191.4 0.0 2.2e-56 190.5 0.0 1.5 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 EGC29009.1 - 1.9e-29 100.4 9.3 5.4e-07 29.2 0.0 6.7 6 0 0 6 6 6 5 WD domain, G-beta repeat Nup160 PF11715.3 EGC29009.1 - 1.2e-06 27.0 3.6 0.0059 14.7 0.4 2.9 2 1 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGC29009.1 - 0.012 14.4 8.5 0.38 9.4 0.0 4.0 1 1 1 4 4 4 0 Nup133 N terminal like DUF1513 PF07433.6 EGC29009.1 - 0.083 11.7 0.0 3 6.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) Cas_Cas1 PF01867.11 EGC29010.1 - 0.048 12.7 0.1 0.05 12.6 0.0 1.0 1 0 0 1 1 1 0 CRISPR associated protein Cas1 EF-hand_4 PF12763.2 EGC29011.1 - 1.3e-18 66.6 0.0 1.3e-18 66.6 0.0 2.6 2 2 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_1 PF00036.27 EGC29011.1 - 0.017 14.3 0.1 0.037 13.3 0.1 1.6 1 0 0 1 1 1 0 EF hand CBFD_NFYB_HMF PF00808.18 EGC29012.1 - 5.4e-20 71.2 0.2 9.5e-20 70.4 0.1 1.4 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC29012.1 - 0.019 15.0 0.0 0.035 14.2 0.0 1.5 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Dimer_Tnp_hAT PF05699.9 EGC29014.1 - 1.3e-12 47.1 0.5 3.3e-12 45.8 0.3 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region CDC37_C PF08564.5 EGC29014.1 - 0.00038 20.2 0.6 0.00064 19.5 0.4 1.3 1 0 0 1 1 1 1 Cdc37 C terminal domain Exonuc_VII_L PF02601.10 EGC29014.1 - 0.65 9.1 4.6 0.85 8.7 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit GDA1_CD39 PF01150.12 EGC29016.1 - 0.033 12.6 1.2 0.053 11.9 0.9 1.3 1 0 0 1 1 1 0 GDA1/CD39 (nucleoside phosphatase) family Toprim PF01751.17 EGC29016.1 - 0.17 11.8 0.8 0.28 11.2 0.0 1.8 2 0 0 2 2 2 0 Toprim domain Imm42 PF15601.1 EGC29017.1 - 0.033 13.6 0.1 0.038 13.4 0.1 1.2 1 1 0 1 1 1 0 Immunity protein 42 zf-RING_2 PF13639.1 EGC29020.1 - 1.8e-11 43.6 8.5 2.8e-11 43.0 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29020.1 - 1.2e-09 37.6 6.2 1.9e-09 37.0 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29020.1 - 2.6e-08 33.7 8.9 4.3e-08 33.0 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29020.1 - 6.5e-08 32.0 9.2 1.3e-07 31.1 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29020.1 - 1.3e-05 24.7 6.6 2.5e-05 23.9 4.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC29020.1 - 7.2e-05 22.8 7.6 0.0002 21.3 5.3 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC29020.1 - 0.00033 20.4 8.5 0.00077 19.2 5.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC29020.1 - 0.0017 17.9 9.9 0.0033 16.9 6.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EGC29020.1 - 0.03 14.3 6.6 0.03 14.3 4.6 2.1 2 0 0 2 2 2 0 zinc-finger zf-RING_6 PF14835.1 EGC29020.1 - 0.032 14.0 2.0 0.063 13.0 1.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EGC29020.1 - 0.11 12.1 7.8 0.3 10.6 5.4 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EGC29020.1 - 0.16 11.6 7.9 0.078 12.7 3.1 2.4 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC29020.1 - 0.17 11.7 5.2 0.46 10.3 3.6 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC29020.1 - 0.29 10.6 8.4 0.52 9.8 5.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-CHY PF05495.7 EGC29020.1 - 0.3 11.2 7.7 0.62 10.2 4.9 1.9 1 1 0 1 1 1 0 CHY zinc finger DZR PF12773.2 EGC29020.1 - 2.1 8.2 6.2 5.9 6.7 3.8 2.0 1 1 1 2 2 2 0 Double zinc ribbon IBR PF01485.16 EGC29020.1 - 4.1 7.3 10.5 35 4.3 7.3 2.5 1 1 0 1 1 1 0 IBR domain RNA_ligase PF09414.5 EGC29022.1 - 1.2e-23 83.8 0.1 2.3e-23 82.9 0.0 1.5 1 0 0 1 1 1 1 RNA ligase Miro PF08477.8 EGC29023.1 - 9.6e-15 55.1 0.0 1.8e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGC29023.1 - 1.6e-08 34.1 0.0 2.7e-08 33.3 0.0 1.4 1 1 0 1 1 1 1 Ras family AAA_14 PF13173.1 EGC29023.1 - 0.00043 20.1 1.3 0.00065 19.6 0.2 1.8 1 1 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGC29023.1 - 0.0018 18.2 0.6 0.005 16.7 0.4 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase KxDL PF10241.4 EGC29023.1 - 0.12 12.2 1.2 0.19 11.6 0.3 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein Mob1_phocein PF03637.12 EGC29024.1 - 1.6e-38 132.1 6.9 2e-38 131.7 4.8 1.1 1 0 0 1 1 1 1 Mob1/phocein family Ribosomal_S14 PF00253.16 EGC29025.1 - 1.1e-17 63.1 4.0 1.1e-17 63.0 2.8 1.0 1 0 0 1 1 1 1 Ribosomal protein S14p/S29e Zn_Tnp_IS1595 PF12760.2 EGC29025.1 - 0.06 13.1 2.5 0.071 12.9 1.7 1.2 1 0 0 1 1 1 0 Transposase zinc-ribbon domain OrfB_Zn_ribbon PF07282.6 EGC29025.1 - 0.11 12.1 0.6 0.13 11.9 0.4 1.1 1 0 0 1 1 1 0 Putative transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EGC29025.1 - 0.5 9.9 2.0 0.85 9.1 1.4 1.4 1 1 0 1 1 1 0 A2L zinc ribbon domain zf-AD PF07776.10 EGC29025.1 - 0.67 9.9 2.9 9.3 6.3 0.1 2.1 1 1 1 2 2 2 0 Zinc-finger associated domain (zf-AD) zf-FPG_IleRS PF06827.9 EGC29025.1 - 2.1 8.0 5.6 7.7 6.2 3.9 1.8 1 1 0 1 1 1 0 Zinc finger found in FPG and IleRS Pkinase PF00069.20 EGC29026.1 - 1.7e-48 165.0 0.0 3.6e-48 163.9 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29026.1 - 3.3e-48 164.0 0.0 5.7e-48 163.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Ank_2 PF12796.2 EGC29026.1 - 1.1e-28 99.3 0.3 5.8e-13 48.9 0.0 3.0 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) C2 PF00168.25 EGC29026.1 - 1.1e-19 70.0 0.0 3.1e-19 68.5 0.0 1.8 1 0 0 1 1 1 1 C2 domain Ank_3 PF13606.1 EGC29026.1 - 4.2e-15 54.3 0.1 0.00028 20.8 0.0 4.7 4 0 0 4 4 4 3 Ankyrin repeat Ank PF00023.25 EGC29026.1 - 6.3e-15 54.1 0.0 0.00028 20.5 0.0 4.8 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EGC29026.1 - 3e-13 49.8 0.0 0.00047 20.6 0.0 4.2 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC29026.1 - 6.4e-10 38.9 2.9 0.00087 19.4 0.0 5.1 3 1 3 6 6 5 2 Ankyrin repeats (many copies) SAM_1 PF00536.25 EGC29026.1 - 4.2e-05 23.6 0.4 0.0001 22.4 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC29026.1 - 0.0032 17.2 0.2 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.18 EGC29026.1 - 0.028 14.1 0.1 0.17 11.5 0.2 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Mucin PF01456.12 EGC29026.1 - 1 9.1 32.0 0.018 14.7 16.6 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein NDT80_PhoG PF05224.7 EGC29027.1 - 3.6e-14 53.1 0.3 3.6e-14 53.1 0.2 6.2 4 3 1 5 5 5 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 EGC29027.1 - 9.7e-12 44.8 0.2 2.4e-11 43.5 0.2 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase DUF4206 PF13901.1 EGC29028.1 - 1.7e-62 210.5 10.0 1.7e-62 210.5 6.9 2.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4206) RUN PF02759.14 EGC29028.1 - 4.9e-13 48.9 0.9 4.8e-12 45.7 0.0 3.0 2 1 0 2 2 2 1 RUN domain Prok-RING_1 PF14446.1 EGC29028.1 - 0.45 10.2 10.7 0.061 13.0 4.1 2.0 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 dUTPase PF00692.14 EGC29029.1 - 2.7e-10 39.8 0.0 5.6e-10 38.7 0.0 1.5 1 1 1 2 2 2 1 dUTPase DCD PF06559.6 EGC29029.1 - 1.3e-05 23.8 0.0 0.017 13.4 0.0 2.0 1 1 1 2 2 2 2 2'-deoxycytidine 5'-triphosphate deaminase (DCD) MAP7 PF05672.6 EGC29030.1 - 1.3 8.3 50.8 0.027 13.8 28.1 2.2 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family CytochromB561_N PF09786.4 EGC29030.1 - 1.6 7.1 15.0 1.8 6.9 10.4 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal SprA-related PF12118.3 EGC29030.1 - 2.7 7.2 31.3 0.22 10.8 18.1 1.6 1 1 1 2 2 2 0 SprA-related family DUF342 PF03961.8 EGC29030.1 - 9.2 4.5 19.5 15 3.8 13.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) CtaG_Cox11 PF04442.9 EGC29032.1 - 9.2e-57 191.1 0.4 1.2e-56 190.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein CtaG/Cox11 RhodobacterPufX PF11511.3 EGC29032.1 - 0.0038 16.5 0.0 0.0061 15.9 0.0 1.3 1 0 0 1 1 1 1 Intrinsic membrane protein PufX Ank_2 PF12796.2 EGC29033.1 - 1.2e-06 28.7 0.0 0.017 15.4 0.0 3.9 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC29033.1 - 0.18 12.1 0.0 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 Ankyrin repeats (many copies) DUF2833 PF11090.3 EGC29033.1 - 3.9 7.7 9.1 12 6.1 0.2 4.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2833) SNARE PF05739.14 EGC29034.1 - 5.6e-18 64.3 3.5 5.6e-18 64.3 2.4 2.5 3 0 0 3 3 3 1 SNARE domain Syntaxin PF00804.20 EGC29034.1 - 1.4e-12 47.6 3.1 1.4e-12 47.6 2.1 3.1 2 1 0 2 2 2 1 Syntaxin TMPIT PF07851.8 EGC29034.1 - 0.0033 16.5 11.9 0.0033 16.5 8.2 2.1 1 1 1 2 2 2 1 TMPIT-like protein Syntaxin-6_N PF09177.6 EGC29034.1 - 0.022 15.1 2.0 0.022 15.1 1.4 3.5 1 1 4 5 5 5 0 Syntaxin 6, N-terminal Syntaxin_2 PF14523.1 EGC29034.1 - 0.05 13.6 15.4 0.049 13.6 3.8 3.0 2 1 0 2 2 2 0 Syntaxin-like protein MCPsignal PF00015.16 EGC29034.1 - 0.074 12.5 8.7 0.057 12.9 0.7 2.6 1 1 2 3 3 3 0 Methyl-accepting chemotaxis protein (MCP) signalling domain ETRAMP PF09716.5 EGC29034.1 - 0.1 12.5 0.4 0.1 12.5 0.3 2.7 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) VitD-bind_III PF09164.5 EGC29034.1 - 0.1 12.1 2.0 0.7 9.5 0.2 2.6 2 0 0 2 2 2 0 Vitamin D binding protein, domain III DUF2116 PF09889.4 EGC29034.1 - 0.19 11.5 1.4 0.47 10.2 1.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Herpes_US9 PF06072.6 EGC29034.1 - 0.2 11.5 0.4 0.34 10.7 0.3 1.4 1 0 0 1 1 1 0 Alphaherpesvirus tegument protein US9 DUF4179 PF13786.1 EGC29034.1 - 1.4 9.1 10.9 5.3 7.3 0.5 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF4179) 6PGD PF00393.14 EGC29035.1 - 8e-134 445.3 0.0 9.6e-134 445.1 0.0 1.1 1 0 0 1 1 1 1 6-phosphogluconate dehydrogenase, C-terminal domain NAD_binding_2 PF03446.10 EGC29035.1 - 3.2e-53 179.9 0.0 4.5e-53 179.4 0.0 1.2 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Shikimate_DH PF01488.15 EGC29035.1 - 0.022 14.8 0.1 0.042 13.9 0.1 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase NAD_binding_11 PF14833.1 EGC29035.1 - 0.061 13.3 0.0 0.16 12.0 0.0 1.7 1 0 0 1 1 1 0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase Hydrolase_6 PF13344.1 EGC29036.1 - 0.048 13.5 0.4 0.21 11.5 0.1 2.2 1 1 1 2 2 2 0 Haloacid dehalogenase-like hydrolase Rxt3 PF08642.5 EGC29036.1 - 0.19 11.9 4.8 0.71 10.1 0.6 2.8 3 0 0 3 3 3 0 Histone deacetylation protein Rxt3 DUF3408 PF11888.3 EGC29036.1 - 0.25 11.2 5.5 0.078 12.9 1.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Spc24 PF08286.6 EGC29036.1 - 1.5 8.5 11.9 0.086 12.5 0.9 3.1 3 0 0 3 3 3 0 Spc24 subunit of Ndc80 Apc13p PF05839.6 EGC29037.1 - 4.4e-06 26.5 2.4 0.0002 21.2 1.7 2.0 1 1 0 1 1 1 1 Apc13p protein Dynamin_M PF01031.15 EGC29038.1 - 1.6e-105 352.1 0.9 1.6e-105 352.1 0.7 1.8 2 0 0 2 2 2 1 Dynamin central region Dynamin_N PF00350.18 EGC29038.1 - 7.5e-59 198.3 0.0 7.5e-59 198.3 0.0 2.7 3 1 0 3 3 3 1 Dynamin family GED PF02212.13 EGC29038.1 - 1e-33 115.0 3.3 1e-33 115.0 2.3 1.9 2 0 0 2 2 2 1 Dynamin GTPase effector domain MMR_HSR1 PF01926.18 EGC29038.1 - 4.1e-05 23.5 0.1 0.0002 21.2 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC29038.1 - 0.018 15.5 0.0 0.055 13.9 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein DUF605 PF04652.11 EGC29038.1 - 5.3 6.3 27.8 7.8 5.7 19.3 1.2 1 0 0 1 1 1 0 Vta1 like CorA PF01544.13 EGC29039.1 - 5.9e-64 215.9 4.4 8.5e-64 215.3 3.1 1.2 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF3440 PF11922.3 EGC29039.1 - 0.1 12.1 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3440) Hexapep PF00132.19 EGC29040.1 - 5e-12 44.7 12.6 0.00019 20.8 0.0 4.5 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGC29040.1 - 0.0002 20.8 2.5 0.0002 20.8 1.8 4.0 5 1 0 5 5 5 1 Hexapeptide repeat of succinyl-transferase Dicty_CTDC PF00526.13 EGC29041.1 - 4.4e-21 74.2 53.8 2.7e-09 36.6 2.2 9.4 9 1 0 9 9 9 5 Dictyostelium (slime mold) repeat WD40 PF00400.27 EGC29042.1 - 1.1e-46 155.0 16.2 4.5e-11 42.1 0.1 10.0 11 0 0 11 11 11 7 WD domain, G-beta repeat Utp12 PF04003.7 EGC29042.1 - 1.6e-25 89.1 0.2 2.8e-25 88.3 0.1 1.4 1 0 0 1 1 1 1 Dip2/Utp12 Family PD40 PF07676.7 EGC29042.1 - 0.0012 18.4 0.0 8.6 6.1 0.0 4.9 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EGC29042.1 - 0.011 15.4 0.0 1.1 9.0 0.0 3.5 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Nucleoplasmin PF03066.10 EGC29042.1 - 9.2 5.7 13.6 1.3 8.5 0.7 2.7 2 0 0 2 2 2 0 Nucleoplasmin Epimerase PF01370.16 EGC29044.1 - 2.9e-17 62.9 0.0 4.6e-17 62.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC29044.1 - 2.3e-16 59.3 0.0 2.8e-16 59.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGC29044.1 - 6.3e-14 52.3 0.2 6.3e-13 49.1 0.1 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC29044.1 - 2.6e-10 39.6 0.0 3.6e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGC29044.1 - 1.7e-07 31.3 0.1 1.1e-06 28.7 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29044.1 - 1.3e-05 24.9 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EGC29044.1 - 0.00031 20.0 0.0 0.00044 19.5 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family Epimerase PF01370.16 EGC29045.1 - 1.4e-20 73.7 0.0 2.1e-20 73.1 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC29045.1 - 7.9e-19 67.4 0.0 9.8e-19 67.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGC29045.1 - 3.8e-14 52.2 0.0 6.6e-14 51.4 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGC29045.1 - 3.8e-13 49.8 0.0 1.1e-12 48.3 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding adh_short PF00106.20 EGC29045.1 - 2.6e-06 27.4 0.2 3.4e-05 23.8 0.0 2.5 2 1 0 2 2 2 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGC29045.1 - 2.3e-05 23.4 0.0 0.00018 20.4 0.0 2.1 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGC29045.1 - 3e-05 23.4 0.0 5.1e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family KR PF08659.5 EGC29045.1 - 8.2e-05 22.3 0.0 0.00025 20.7 0.0 1.8 1 1 0 1 1 1 1 KR domain ThiC PF01964.13 EGC29045.1 - 0.15 10.5 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 ThiC family Epimerase PF01370.16 EGC29046.1 - 1.7e-19 70.1 0.0 4.8e-19 68.7 0.0 1.7 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC29046.1 - 1.1e-16 60.3 0.0 1.4e-16 60.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGC29046.1 - 4.2e-14 52.9 0.3 3.2e-13 50.1 0.2 2.0 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC29046.1 - 2.7e-11 42.9 0.0 3.5e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGC29046.1 - 8.2e-09 35.5 0.0 2e-08 34.3 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29046.1 - 5.3e-07 29.4 0.0 1.1e-06 28.4 0.0 1.5 1 0 0 1 1 1 1 KR domain NmrA PF05368.8 EGC29046.1 - 4.1e-05 22.9 0.0 9.1e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EGC29046.1 - 0.006 15.5 0.0 0.017 14.0 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein DUF4433 PF14487.1 EGC29046.1 - 0.047 13.4 0.0 0.1 12.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4433) NapE PF06796.6 EGC29047.1 - 0.38 10.0 2.6 0.79 9.0 1.8 1.5 1 0 0 1 1 1 0 Periplasmic nitrate reductase protein NapE Nebulin PF00880.13 EGC29047.1 - 0.74 9.5 3.4 3.3 7.4 0.6 2.9 2 0 0 2 2 2 0 Nebulin repeat Epimerase PF01370.16 EGC29048.1 - 5.6e-20 71.7 0.0 8.6e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC29048.1 - 3.1e-17 62.1 0.0 3.6e-17 61.9 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGC29048.1 - 2.1e-14 53.9 0.1 8.2e-14 52.0 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC29048.1 - 1.9e-10 40.1 0.0 2.5e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Male sterility protein adh_short PF00106.20 EGC29048.1 - 2.1e-05 24.5 0.1 0.00017 21.5 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29048.1 - 0.0004 20.0 0.0 0.001 18.7 0.0 1.6 1 1 0 1 1 1 1 KR domain NmrA PF05368.8 EGC29048.1 - 0.0033 16.7 0.0 0.005 16.1 0.0 1.4 1 0 0 1 1 1 1 NmrA-like family Polysacc_synt_2 PF02719.10 EGC29048.1 - 0.017 14.0 0.0 0.031 13.1 0.0 1.4 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein NAD_binding_7 PF13241.1 EGC29048.1 - 0.12 12.6 0.0 0.21 11.8 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding DnaJ PF00226.26 EGC29049.1 - 1.4e-23 82.3 0.5 3.5e-23 81.1 0.3 1.7 1 0 0 1 1 1 1 DnaJ domain CENP-T PF15511.1 EGC29049.1 - 0.008 15.4 11.9 0.0098 15.1 8.3 1.3 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Nop14 PF04147.7 EGC29049.1 - 0.046 11.6 34.9 0.0029 15.6 20.7 1.5 2 0 0 2 2 2 0 Nop14-like family DUF2890 PF11081.3 EGC29049.1 - 8.9 6.3 25.1 1.3 9.0 14.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) HA2 PF04408.18 EGC29050.1 - 1.9e-19 69.5 0.0 1.9e-19 69.5 0.0 2.8 3 0 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGC29050.1 - 1.6e-15 56.7 0.0 7.2e-15 54.6 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain RWD PF05773.17 EGC29050.1 - 5.5e-13 48.7 1.8 5.5e-13 48.7 1.3 2.9 2 0 0 2 2 2 1 RWD domain OB_NTP_bind PF07717.11 EGC29050.1 - 7.2e-12 45.1 0.0 5.2e-11 42.3 0.0 2.5 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGC29050.1 - 5.3e-10 39.0 0.1 7.5e-09 35.2 0.0 2.4 2 0 0 2 2 2 1 DEAD/DEAH box helicase DND1_DSRM PF14709.1 EGC29050.1 - 6.7e-06 26.2 0.5 3.9e-05 23.8 0.5 2.3 2 0 0 2 2 2 1 double strand RNA binding domain from DEAD END PROTEIN 1 AAA_22 PF13401.1 EGC29050.1 - 0.0006 19.9 1.3 0.0046 17.0 0.4 2.9 2 1 0 2 2 2 1 AAA domain dsrm PF00035.20 EGC29050.1 - 0.016 15.7 2.8 0.018 15.5 0.5 2.4 2 0 0 2 2 2 0 Double-stranded RNA binding motif AAA_19 PF13245.1 EGC29050.1 - 0.17 11.6 0.0 0.36 10.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain RuvA_C PF07499.8 EGC29050.1 - 0.2 11.8 0.0 4.8 7.4 0.0 2.6 2 0 0 2 2 2 0 RuvA, C-terminal domain TRAP-gamma PF07074.7 EGC29051.1 - 5.2e-24 84.6 8.1 6.3e-24 84.4 5.6 1.1 1 0 0 1 1 1 1 Translocon-associated protein, gamma subunit (TRAP-gamma) CLU PF13236.1 EGC29051.1 - 0.045 13.1 0.2 0.23 10.8 0.1 1.8 1 1 1 2 2 2 0 Clustered mitochondria bPH_3 PF14470.1 EGC29051.1 - 0.06 13.6 0.3 0.75 10.0 0.0 2.5 2 1 1 3 3 3 0 Bacterial PH domain Syndecan PF01034.15 EGC29051.1 - 0.23 11.1 2.4 6.8 6.4 0.1 2.8 2 1 1 3 3 3 0 Syndecan domain DUF2628 PF10947.3 EGC29051.1 - 0.62 9.8 3.9 0.75 9.6 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2628) DUF3796 PF12676.2 EGC29051.1 - 1 9.6 8.4 0.25 11.5 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3796) 2OG-FeII_Oxy PF03171.15 EGC29052.1 - 0.0019 18.4 0.0 0.0039 17.4 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGC29052.1 - 0.0053 17.2 0.0 0.015 15.8 0.0 1.8 2 1 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal ApbA PF02558.11 EGC29053.1 - 0.11 11.9 0.3 0.24 10.8 0.2 1.7 1 1 0 1 1 1 0 Ketopantoate reductase PanE/ApbA WD40 PF00400.27 EGC29054.1 - 5.8e-50 165.4 21.9 1.2e-09 37.6 0.1 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGC29054.1 - 0.00036 20.3 0.1 0.79 9.4 0.0 2.9 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EGC29055.1 - 5.1e-20 70.8 0.3 5.5e-20 70.7 0.2 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC29055.1 - 6.6e-13 48.4 0.0 7.1e-13 48.3 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC29055.1 - 5.5e-08 32.5 0.1 6.3e-08 32.3 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC29055.1 - 0.0074 16.0 0.0 0.0082 15.8 0.0 1.1 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Sod_Fe_C PF02777.13 EGC29056.1 - 2.2e-25 88.5 0.7 5e-25 87.3 0.2 1.8 1 1 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGC29056.1 - 6.5e-10 39.1 0.8 6.5e-10 39.1 0.5 2.2 2 1 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain EMP70 PF02990.11 EGC29057.1 - 6.2e-162 539.7 19.8 6.2e-162 539.7 13.8 1.6 2 0 0 2 2 2 1 Endomembrane protein 70 CagX PF03524.10 EGC29057.1 - 0.11 11.7 0.1 0.19 11.0 0.0 1.2 1 0 0 1 1 1 0 Conjugal transfer protein PALP PF00291.20 EGC29058.1 - 3.8e-83 279.2 0.0 1.1e-69 234.9 0.2 3.5 3 1 0 3 3 3 3 Pyridoxal-phosphate dependent enzyme ACT_5 PF13710.1 EGC29058.1 - 0.019 14.7 0.3 2 8.2 0.1 2.6 2 0 0 2 2 2 0 ACT domain ACT PF01842.20 EGC29058.1 - 0.069 12.6 0.0 7.5 6.1 0.0 2.7 2 0 0 2 2 2 0 ACT domain PSDC PF12588.3 EGC29058.1 - 0.11 12.1 0.4 0.85 9.2 0.0 2.6 3 0 0 3 3 3 0 Phophatidylserine decarboxylase OTCace PF00185.19 EGC29058.1 - 0.11 12.3 0.0 0.35 10.7 0.0 1.9 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain DUF3278 PF11683.3 EGC29059.1 - 0.043 13.7 1.8 0.073 13.0 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) DUF4131 PF13567.1 EGC29059.1 - 0.045 13.1 0.0 0.049 13.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF4446 PF14584.1 EGC29059.1 - 0.092 12.5 1.6 0.16 11.8 1.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) WBP-1 PF11669.3 EGC29059.1 - 0.11 12.5 0.5 12 6.0 0.2 2.3 2 0 0 2 2 2 0 WW domain-binding protein 1 Wzy_C PF04932.10 EGC29059.1 - 1.4 8.6 5.3 5.7 6.7 3.5 1.9 1 1 0 1 1 1 0 O-Antigen ligase Mem_trans PF03547.13 EGC29060.1 - 0.014 13.7 0.5 0.018 13.3 0.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Mucin PF01456.12 EGC29060.1 - 0.036 13.8 3.8 0.054 13.2 2.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Tmemb_185A PF10269.4 EGC29060.1 - 0.13 11.8 4.2 0.19 11.2 2.9 1.3 1 0 0 1 1 1 0 Transmembrane Fragile-X-F protein Rho_Binding PF08912.6 EGC29060.1 - 0.83 9.9 9.5 0.49 10.7 0.2 2.9 3 0 0 3 3 3 0 Rho Binding vMSA PF00695.14 EGC29060.1 - 4.9 6.2 9.5 0.55 9.3 1.0 2.1 1 1 1 2 2 2 0 Major surface antigen from hepadnavirus NUDIX PF00293.23 EGC29062.1 - 2.7e-07 30.3 0.0 4.5e-07 29.5 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain FNIP PF05725.7 EGC29063.1 - 5.3e-49 163.9 50.8 1.7e-06 27.8 0.1 11.6 1 1 15 17 17 17 17 FNIP Repeat Pro_isomerase PF00160.16 EGC29063.1 - 0.00066 19.9 0.1 22 5.2 0.0 6.0 9 0 0 9 9 9 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BSD PF03909.12 EGC29063.1 - 0.037 13.7 0.0 67 3.3 0.0 4.8 7 0 0 7 7 7 0 BSD domain Acetyltransf_7 PF13508.1 EGC29065.1 - 9.7e-05 22.4 0.0 0.0017 18.4 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC29065.1 - 0.0003 20.7 0.0 0.0024 17.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family RAP PF08373.5 EGC29065.1 - 0.012 15.4 0.3 1.6 8.6 0.0 2.9 2 0 0 2 2 2 0 RAP domain Acetyltransf_CG PF14542.1 EGC29065.1 - 0.035 13.9 0.0 0.17 11.8 0.0 2.0 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase AFG1_ATPase PF03969.11 EGC29066.1 - 5.8e-101 337.9 1.3 8.4e-97 324.2 0.0 2.7 1 1 0 2 2 2 2 AFG1-like ATPase AAA_16 PF13191.1 EGC29066.1 - 0.0024 17.8 0.0 0.12 12.3 0.0 2.8 2 1 1 3 3 3 1 AAA ATPase domain ABC_tran PF00005.22 EGC29066.1 - 0.028 14.7 0.1 0.48 10.7 0.0 2.9 1 1 1 2 2 2 0 ABC transporter AAA_22 PF13401.1 EGC29066.1 - 0.042 14.0 0.0 0.2 11.7 0.0 2.3 2 1 0 2 2 2 0 AAA domain DUF1616 PF07760.6 EGC29066.1 - 0.31 10.1 3.5 0.64 9.0 2.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1616) DUF2009 PF09418.5 EGC29067.1 - 5.2e-211 701.3 0.8 6.6e-211 700.9 0.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2009) zf-B_box PF00643.19 EGC29067.1 - 0.00073 19.3 8.3 0.00073 19.3 5.8 1.7 2 0 0 2 2 2 1 B-box zinc finger Sporozoite_P67 PF05642.6 EGC29067.1 - 0.39 8.5 2.9 0.6 7.9 2.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen zf-DHHC PF01529.15 EGC29068.1 - 8e-39 132.8 16.8 8e-39 132.8 11.7 2.8 1 1 1 2 2 2 1 DHHC palmitoyltransferase DUF4199 PF13858.1 EGC29068.1 - 0.017 15.0 2.3 0.017 15.0 1.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF4199) ERK-JNK_inhib PF15002.1 EGC29068.1 - 0.082 12.2 0.0 0.16 11.3 0.0 1.4 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor DZR PF12773.2 EGC29068.1 - 1.3 8.8 7.8 2.2 8.1 5.4 1.3 1 0 0 1 1 1 0 Double zinc ribbon Oxidored_FMN PF00724.15 EGC29069.1 - 0.0014 17.7 0.0 0.0015 17.6 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF3500 PF12006.3 EGC29069.1 - 0.085 11.7 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3500) zf-CCHC PF00098.18 EGC29070.1 - 3.4e-06 26.7 1.4 5.4e-06 26.0 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC29070.1 - 0.037 13.6 1.3 0.16 11.6 0.1 2.4 2 0 0 2 2 2 0 Zinc knuckle TMEM154 PF15102.1 EGC29071.1 - 0.0079 15.9 0.1 0.015 15.0 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family EphA2_TM PF14575.1 EGC29071.1 - 0.0081 16.5 0.3 0.024 15.0 0.2 1.7 1 0 0 1 1 1 1 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.5 EGC29071.1 - 0.018 15.1 2.8 0.024 14.7 0.3 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Baculo_11_kDa PF06143.6 EGC29071.1 - 0.043 13.1 2.7 0.29 10.5 0.7 2.8 3 0 0 3 3 3 0 Baculovirus 11 kDa family HemY_N PF07219.8 EGC29071.1 - 0.055 13.0 0.1 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 HemY protein N-terminus DUF3357 PF11837.3 EGC29071.1 - 0.09 12.6 0.0 0.16 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) DUF1191 PF06697.7 EGC29071.1 - 0.12 11.1 0.0 0.16 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) NicO PF03824.11 EGC29071.1 - 0.15 11.3 0.0 0.22 10.8 0.0 1.2 1 0 0 1 1 1 0 High-affinity nickel-transport protein DUF912 PF06024.7 EGC29071.1 - 1.5 8.9 10.2 0.043 13.8 1.5 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Cpn60_TCP1 PF00118.19 EGC29072.1 - 6.5e-96 321.8 16.8 8.8e-96 321.4 11.6 1.1 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 EGC29073.1 - 3.4e-55 185.8 0.0 3.9e-55 185.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC29073.1 - 1.5e-17 64.2 0.0 2e-17 63.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC29073.1 - 2e-08 33.6 0.0 2.1e-08 33.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC29073.1 - 3.8e-05 23.2 0.0 0.00075 18.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC29073.1 - 4e-05 23.5 0.0 5e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC29073.1 - 0.042 13.0 0.0 0.058 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EGC29073.1 - 0.072 12.0 0.0 0.12 11.3 0.0 1.3 1 0 0 1 1 1 0 Septin SRPRB PF09439.5 EGC29073.1 - 0.074 12.2 0.0 0.097 11.8 0.0 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AIG1 PF04548.11 EGC29073.1 - 0.079 12.0 0.0 0.15 11.1 0.0 1.5 1 0 0 1 1 1 0 AIG1 family AAA_25 PF13481.1 EGC29073.1 - 0.095 12.0 0.0 0.27 10.6 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC29073.1 - 0.097 12.2 0.1 0.13 11.8 0.0 1.3 1 1 0 1 1 1 0 AAA domain Peptidase_M76 PF09768.4 EGC29074.1 - 2.1e-51 173.8 2.5 3.4e-51 173.1 1.7 1.3 1 0 0 1 1 1 1 Peptidase M76 family Pkinase PF00069.20 EGC29075.1 - 1.1e-68 231.2 0.0 1.1e-68 231.2 0.0 2.1 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29075.1 - 6e-45 153.3 0.0 1.2e-44 152.3 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC29075.1 - 0.14 11.9 0.0 1.5 8.4 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC29075.1 - 0.15 11.1 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family AAA_18 PF13238.1 EGC29076.1 - 2.4e-12 47.2 0.2 4e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC29076.1 - 3.7e-11 43.1 0.0 4.9e-11 42.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC29076.1 - 7.1e-11 42.9 0.0 9.6e-11 42.5 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC29076.1 - 0.00055 19.0 0.0 0.00098 18.2 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin CoaE PF01121.15 EGC29076.1 - 0.0007 19.0 0.1 0.0035 16.7 0.0 2.0 1 1 1 2 2 2 1 Dephospho-CoA kinase AAA_14 PF13173.1 EGC29076.1 - 0.0084 16.0 0.1 0.015 15.2 0.1 1.5 1 0 0 1 1 1 1 AAA domain ADK PF00406.17 EGC29076.1 - 0.04 13.8 0.0 0.052 13.4 0.0 1.2 1 0 0 1 1 1 0 Adenylate kinase AAA_22 PF13401.1 EGC29076.1 - 0.077 13.1 0.1 0.14 12.2 0.0 1.6 1 1 0 1 1 1 0 AAA domain RRM_1 PF00076.17 EGC29077.1 - 1.7e-51 171.7 9.3 2.8e-15 55.6 0.0 5.7 5 1 1 6 6 6 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC29077.1 - 5.1e-45 151.3 2.6 7.6e-13 48.2 0.0 4.9 4 1 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC29077.1 - 7.8e-22 76.8 6.7 1.1e-06 28.3 0.0 5.0 4 1 1 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MMR_HSR1 PF01926.18 EGC29078.1 - 1.5e-05 24.9 0.7 0.00064 19.6 0.3 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGC29078.1 - 0.00019 21.9 0.2 0.09 13.2 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EGC29078.1 - 0.00021 20.7 0.1 0.003 16.9 0.0 2.2 2 0 0 2 2 2 1 Ras family WD40 PF00400.27 EGC29079.1 - 6.1e-21 73.4 4.2 0.00018 21.2 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat eIF2A PF08662.6 EGC29079.1 - 6.6e-05 22.7 0.8 0.13 12.0 0.0 3.8 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A PD40 PF07676.7 EGC29079.1 - 0.025 14.2 0.2 29 4.4 0.0 4.5 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat 14-3-3 PF00244.15 EGC29080.1 - 6.8e-117 388.6 6.3 8e-117 388.4 4.3 1.0 1 0 0 1 1 1 1 14-3-3 protein DUF837 PF05769.6 EGC29080.1 - 0.031 13.7 6.8 0.055 13.0 0.3 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF837) AAA_19 PF13245.1 EGC29081.1 - 0.00023 20.8 0.0 0.00041 20.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGC29081.1 - 0.16 11.9 0.0 0.35 10.8 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain PAP1 PF08601.5 EGC29082.1 - 1.4 8.5 17.0 1.6 8.3 11.8 1.0 1 0 0 1 1 1 0 Transcription factor PAP1 Isochorismatase PF00857.15 EGC29083.1 - 6.9e-31 107.5 0.0 8.2e-31 107.2 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family FNIP PF05725.7 EGC29084.1 - 3.3e-79 260.6 83.5 2e-11 43.6 2.5 12.2 11 1 1 12 12 12 12 FNIP Repeat DUF1769 PF08588.5 EGC29084.1 - 3.6e-05 23.6 14.8 1.7 8.6 0.1 8.9 5 2 7 12 12 12 3 Protein of unknown function (DUF1769) LRR_8 PF13855.1 EGC29084.1 - 0.15 11.8 0.0 0.15 11.8 0.0 6.7 4 1 1 6 6 6 0 Leucine rich repeat COG6 PF06419.6 EGC29085.1 - 4.3e-120 401.7 36.0 1.8e-118 396.3 25.0 2.0 1 1 0 1 1 1 1 Conserved oligomeric complex COG6 YicC_N PF03755.8 EGC29085.1 - 0.24 11.3 2.9 1.6 8.6 0.2 2.7 2 1 0 2 2 2 0 YicC-like family, N-terminal region TRAM_LAG1_CLN8 PF03798.11 EGC29086.1 - 5.6e-25 88.0 13.0 5.6e-25 88.0 9.0 1.9 2 0 0 2 2 2 1 TLC domain DUF165 PF02592.10 EGC29086.1 - 0.014 15.5 0.0 0.04 14.1 0.0 1.9 1 0 0 1 1 1 0 Uncharacterized ACR, YhhQ family COG1738 p450 PF00067.17 EGC29087.1 - 1.7e-76 257.6 1.5 2e-76 257.3 1.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-bind_6 PF13921.1 EGC29088.1 - 2e-26 91.8 11.8 1e-14 54.3 0.2 4.1 4 1 1 5 5 5 3 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGC29088.1 - 6.2e-26 90.2 10.7 3.2e-13 49.5 0.5 3.9 3 1 0 3 3 3 3 Myb-like DNA-binding domain MSA-2c PF12238.3 EGC29088.1 - 0.0012 18.5 10.4 0.0065 16.1 3.4 2.2 1 1 1 2 2 2 2 Merozoite surface antigen 2c DUF445 PF04286.7 EGC29088.1 - 0.026 14.0 1.1 0.82 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF445) Myb_DNA-bind_4 PF13837.1 EGC29088.1 - 0.032 14.3 16.3 0.15 12.2 0.5 4.0 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain DIT1_PvcA PF05141.7 EGC29088.1 - 0.058 12.6 0.2 8.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Ribosomal_L18_c PF14204.1 EGC29088.1 - 0.17 12.4 4.6 0.15 12.6 0.7 2.4 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Myb_DNA-bind_5 PF13873.1 EGC29088.1 - 0.53 10.2 7.6 5.5 6.9 0.3 3.9 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain MADF_DNA_bdg PF10545.4 EGC29088.1 - 1.9 8.6 4.8 19 5.5 0.0 3.0 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SH3_9 PF14604.1 EGC29089.1 - 1.1e-12 47.2 0.0 1.3e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC29089.1 - 1.4e-11 43.6 0.0 1.5e-11 43.4 0.0 1.1 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC29089.1 - 1.4e-11 43.7 0.0 1.7e-11 43.4 0.0 1.0 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC29090.1 - 4.1e-08 32.5 0.0 6.6e-08 31.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGC29090.1 - 3.4e-06 26.5 0.0 5.2e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC29090.1 - 0.0013 18.0 0.0 0.0028 17.0 0.0 1.5 1 0 0 1 1 1 1 SH3 domain TetR_N PF00440.18 EGC29090.1 - 0.094 12.3 0.1 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Bacterial regulatory proteins, tetR family Peptidase_S24 PF00717.18 EGC29090.1 - 0.21 11.2 0.1 0.21 11.2 0.0 1.8 2 0 0 2 2 2 0 Peptidase S24-like Nexin_C PF08628.7 EGC29090.1 - 0.22 11.6 2.2 0.65 10.0 0.9 2.0 1 1 1 2 2 2 0 Sorting nexin C terminal Plant_all_beta PF10532.4 EGC29090.1 - 0.72 9.9 6.0 0.61 10.1 2.5 2.0 1 1 0 2 2 2 0 Plant specific N-all beta domain Trypan_glycop PF00913.14 EGC29090.1 - 2.1 7.1 7.5 2.7 6.8 5.2 1.1 1 0 0 1 1 1 0 Trypanosome variant surface glycoprotein (A-type) Myosin_tail_1 PF01576.14 EGC29091.1 - 0.0081 13.9 0.7 0.0081 13.9 0.5 1.7 2 0 0 2 2 2 1 Myosin tail HHH_4 PF14490.1 EGC29091.1 - 0.11 12.3 0.9 0.18 11.6 0.2 1.8 2 0 0 2 2 2 0 Helix-hairpin-helix containing domain IPP-2 PF04979.9 EGC29092.1 - 3.7e-12 46.6 29.6 4.2e-08 33.4 10.2 3.6 2 2 1 3 3 3 2 Protein phosphatase inhibitor 2 (IPP-2) UQ_con PF00179.21 EGC29093.1 - 9.9e-43 144.9 0.0 1.1e-42 144.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC29093.1 - 0.01 15.5 0.0 0.012 15.3 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B RWD PF05773.17 EGC29093.1 - 0.024 14.5 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 RWD domain Pro_isomerase PF00160.16 EGC29094.1 - 5.3e-36 124.1 0.1 7.2e-36 123.7 0.0 1.2 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Ig_Tie2_1 PF10430.4 EGC29094.1 - 0.051 13.9 0.0 0.09 13.1 0.0 1.3 1 0 0 1 1 1 0 Tie-2 Ig-like domain 1 zf-DHHC PF01529.15 EGC29095.1 - 7.7e-43 145.8 7.2 1.1e-42 145.3 5.0 1.2 1 0 0 1 1 1 1 DHHC palmitoyltransferase Pho86 PF11124.3 EGC29095.1 - 0.015 14.3 2.1 0.021 13.8 1.5 1.2 1 0 0 1 1 1 0 Inorganic phosphate transporter Pho86 DUF1980 PF09323.5 EGC29095.1 - 0.23 11.1 6.4 0.98 9.1 3.8 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) DUF3675 PF12428.3 EGC29095.1 - 0.27 11.4 13.3 0.1 12.8 5.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3675) DZR PF12773.2 EGC29095.1 - 0.88 9.4 8.4 1.4 8.7 5.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon FYVE PF01363.16 EGC29095.1 - 3.1 7.7 12.9 6 6.8 8.9 1.6 1 1 0 1 1 1 0 FYVE zinc finger zf-ribbon_3 PF13248.1 EGC29095.1 - 5.3 6.3 7.7 9.8 5.5 5.3 1.4 1 0 0 1 1 1 0 zinc-ribbon domain SH3_1 PF00018.23 EGC29096.1 - 9.7e-14 50.4 0.0 2.4e-13 49.2 0.0 1.7 1 0 0 1 1 1 1 SH3 domain IMD PF08397.6 EGC29096.1 - 2.5e-12 46.6 10.1 3.2e-12 46.2 7.0 1.1 1 0 0 1 1 1 1 IRSp53/MIM homology domain SH3_9 PF14604.1 EGC29096.1 - 2.8e-10 39.6 0.0 5.2e-10 38.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC29096.1 - 1.3e-07 30.9 0.0 3.1e-07 29.7 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain TSC22 PF01166.13 EGC29096.1 - 0.039 13.9 2.9 0.046 13.6 0.3 2.5 2 0 0 2 2 2 0 TSC-22/dip/bun family zf-C3Hc3H PF13891.1 EGC29097.1 - 8.4e-08 32.1 5.4 1.8e-07 31.1 3.8 1.5 1 0 0 1 1 1 1 Potential DNA-binding domain zf-TRM13_CCCH PF11722.3 EGC29097.1 - 2.7e-05 23.4 7.4 0.0031 16.8 0.3 2.5 2 0 0 2 2 2 2 CCCH zinc finger in TRM13 protein zf-primase PF09329.6 EGC29097.1 - 0.099 12.2 7.2 0.069 12.7 1.8 2.8 2 0 0 2 2 2 0 Primase zinc finger HALZ PF02183.13 EGC29097.1 - 0.42 10.3 7.7 1.8 8.3 0.6 2.5 1 1 1 2 2 2 0 Homeobox associated leucine zipper CHD5 PF04420.9 EGC29097.1 - 4 7.0 8.4 0.12 12.0 0.5 2.1 2 0 0 2 2 2 0 CHD5-like protein GATA PF00320.22 EGC29098.1 - 1.7e-15 56.0 4.0 4.8e-15 54.6 2.8 1.8 1 0 0 1 1 1 1 GATA zinc finger NMD3 PF04981.8 EGC29098.1 - 0.016 14.3 1.5 0.55 9.2 0.1 2.3 2 0 0 2 2 2 0 NMD3 family WD40 PF00400.27 EGC29100.1 - 1.2e-42 142.2 15.9 3e-12 45.9 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGC29100.1 - 2.1e-05 24.3 0.0 0.00012 21.8 0.0 2.0 1 1 1 2 2 2 1 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGC29100.1 - 0.0039 15.4 0.1 0.56 8.2 0.0 2.6 3 0 0 3 3 3 2 Nucleoporin Nup120/160 DnaJ PF00226.26 EGC29101.1 - 3e-15 55.6 0.7 8.3e-15 54.2 0.5 1.8 1 0 0 1 1 1 1 DnaJ domain DUF4339 PF14237.1 EGC29101.1 - 1.1e-08 34.5 1.5 1.5e-08 34.0 0.1 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF4339) KTSC PF13619.1 EGC29101.1 - 0.019 14.5 0.3 4.7 6.9 0.0 2.9 2 0 0 2 2 2 0 KTSC domain TFIIA PF03153.8 EGC29101.1 - 4.2 7.1 14.9 8.1 6.2 10.4 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit FNIP PF05725.7 EGC29102.1 - 8.7e-45 150.4 45.4 4.3e-06 26.5 0.3 9.6 1 1 8 12 12 12 12 FNIP Repeat Tubulin-binding PF00418.14 EGC29102.1 - 0.064 12.9 5.0 1.8e+02 1.9 0.0 6.5 7 0 0 7 7 7 0 Tau and MAP protein, tubulin-binding repeat PSI_PsaF PF02507.10 EGC29102.1 - 0.28 10.7 0.7 56 3.2 0.0 3.6 4 0 0 4 4 4 0 Photosystem I reaction centre subunit III 7tm_3 PF00003.17 EGC29103.1 - 1.1e-31 109.9 25.5 1.7e-31 109.3 17.7 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC29103.1 - 7.1e-16 57.8 11.1 1.4e-15 56.8 7.7 1.5 1 0 0 1 1 1 1 Basic membrane protein Glycos_transf_2 PF00535.21 EGC29105.1 - 3.2e-20 72.4 1.0 3.2e-20 72.4 0.7 2.1 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGC29105.1 - 1.3e-05 25.1 0.0 2.2e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Tau95 PF09734.4 EGC29108.1 - 2.3e-61 207.8 2.8 2.3e-61 207.8 2.0 2.8 2 1 0 2 2 2 1 RNA polymerase III transcription factor (TF)IIIC subunit Sel1 PF08238.7 EGC29109.1 - 3.9e-06 27.3 5.0 0.11 13.2 0.1 4.7 6 0 0 6 6 6 2 Sel1 repeat TPR_17 PF13431.1 EGC29109.1 - 8.5e-05 22.4 6.9 0.48 10.7 0.0 6.7 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC29109.1 - 0.0047 16.5 7.7 0.053 13.1 0.0 4.8 5 1 1 6 6 6 1 TPR repeat TPR_1 PF00515.23 EGC29109.1 - 0.0078 15.7 1.4 0.18 11.4 0.0 3.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGC29109.1 - 0.034 14.2 0.0 0.16 12.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC29109.1 - 0.049 14.1 1.9 6.6 7.4 0.0 4.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC29109.1 - 5.3 7.2 8.0 6.3 6.9 0.0 4.6 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29109.1 - 6.5 6.7 17.8 15 5.6 0.0 6.8 6 0 0 6 6 6 0 Tetratricopeptide repeat PH PF00169.24 EGC29112.1 - 0.014 15.5 0.0 0.037 14.2 0.0 1.7 1 0 0 1 1 1 0 PH domain LRR_6 PF13516.1 EGC29113.1 - 1.6e-40 132.5 54.5 5.8e-05 22.7 0.3 14.7 14 0 0 14 14 14 12 Leucine Rich repeat LRR_4 PF12799.2 EGC29113.1 - 4.8e-08 32.4 51.5 0.0021 17.6 0.1 9.5 3 2 9 12 12 12 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC29113.1 - 2.1e-06 27.3 44.6 0.0045 16.7 0.6 8.1 5 2 5 10 10 10 5 Leucine rich repeat LRR_1 PF00560.28 EGC29113.1 - 4.8e-06 25.8 31.6 1.3 9.3 0.0 12.8 13 1 0 13 13 13 3 Leucine Rich Repeat Macoilin PF09726.4 EGC29113.1 - 0.0038 15.5 14.9 0.0056 15.0 10.4 1.3 1 0 0 1 1 1 1 Transmembrane protein F-box-like PF12937.2 EGC29113.1 - 0.015 15.0 0.3 0.029 14.0 0.2 1.4 1 0 0 1 1 1 0 F-box-like Otopetrin PF03189.8 EGC29113.1 - 0.67 8.8 5.5 1.2 8.1 3.8 1.4 1 0 0 1 1 1 0 Otopetrin ketoacyl-synt PF00109.21 EGC29114.1 - 6.4e-71 238.8 0.0 2.2e-70 237.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC29114.1 - 1.7e-53 182.0 0.0 2.5e-53 181.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain PS-DH PF14765.1 EGC29114.1 - 5.7e-34 117.6 0.0 8.2e-34 117.0 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGC29114.1 - 2.2e-31 108.9 0.0 3.6e-31 108.2 0.0 1.4 1 0 0 1 1 1 1 KR domain Ketoacyl-synt_C PF02801.17 EGC29114.1 - 1.8e-28 98.7 0.0 5.1e-28 97.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain adh_short PF00106.20 EGC29114.1 - 2.4e-22 79.6 0.0 4.4e-22 78.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Chal_sti_synt_C PF02797.10 EGC29114.1 - 5.7e-22 78.2 0.0 1.6e-20 73.5 0.0 2.8 2 0 0 2 2 2 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EGC29114.1 - 1e-19 70.6 0.9 3.5e-19 68.9 0.1 2.2 2 0 0 2 2 2 1 Chalcone and stilbene synthases, N-terminal domain ADH_zinc_N PF00107.21 EGC29114.1 - 2.2e-14 53.1 0.0 5.2e-14 51.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase FAE1_CUT1_RppA PF08392.7 EGC29114.1 - 9.4e-14 51.1 0.5 2e-13 50.0 0.3 1.5 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein PP-binding PF00550.20 EGC29114.1 - 6.4e-10 39.1 0.2 2.5e-09 37.2 0.1 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site ADH_N PF08240.7 EGC29114.1 - 8.3e-10 38.4 0.0 2e-09 37.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III_C PF08541.5 EGC29114.1 - 4.4e-08 33.0 0.0 8.6e-06 25.6 0.0 2.8 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_zinc_N_2 PF13602.1 EGC29114.1 - 6.1e-08 33.6 0.0 1.9e-07 32.0 0.0 1.9 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC29114.1 - 2.4e-05 23.4 0.8 5.7e-05 22.2 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain ACP_syn_III PF08545.5 EGC29114.1 - 0.1 12.2 1.2 0.89 9.2 0.1 2.5 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III RA PF00788.18 EGC29115.1 - 0.08 13.4 0.0 0.1 13.0 0.0 1.3 1 0 0 1 1 1 0 Ras association (RalGDS/AF-6) domain End_tail_spike PF12219.3 EGC29115.1 - 0.095 12.5 0.0 0.11 12.3 0.0 1.1 1 0 0 1 1 1 0 Catalytic domain of bacteriophage endosialidase Adap_comp_sub PF00928.16 EGC29116.1 - 4.4e-89 298.0 0.0 5.4e-89 297.7 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGC29116.1 - 1.9e-09 37.3 1.5 3.2e-09 36.6 1.0 1.3 1 0 0 1 1 1 1 Clathrin adaptor complex small chain TIR_2 PF13676.1 EGC29117.1 - 1.9e-21 76.1 0.0 4.9e-20 71.5 0.0 2.8 3 0 0 3 3 3 1 TIR domain RCC1 PF00415.13 EGC29117.1 - 5.5e-14 52.1 6.6 6.5e-08 32.6 0.1 4.8 4 1 0 4 4 4 3 Regulator of chromosome condensation (RCC1) repeat Ank PF00023.25 EGC29117.1 - 1.5e-08 33.9 0.0 0.062 13.1 0.0 3.7 3 0 0 3 3 3 2 Ankyrin repeat TIR PF01582.15 EGC29117.1 - 2.1e-07 30.4 0.1 2.1e-07 30.4 0.1 2.7 3 0 0 3 3 3 1 TIR domain BRCT PF00533.21 EGC29117.1 - 3.4e-07 30.3 3.6 1e-06 28.7 0.6 3.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Ank_2 PF12796.2 EGC29117.1 - 4.7e-07 30.0 0.0 3.6e-06 27.2 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) RCC1_2 PF13540.1 EGC29117.1 - 1.6e-06 27.5 8.5 0.0085 15.6 0.0 4.6 3 1 0 3 3 3 1 Regulator of chromosome condensation (RCC1) repeat Ank_5 PF13857.1 EGC29117.1 - 0.061 13.6 2.2 0.14 12.4 0.0 2.8 3 0 0 3 3 3 0 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC29117.1 - 0.065 13.7 0.0 1.5 9.4 0.0 2.7 1 1 1 2 2 2 0 Ankyrin repeats (many copies) Myosin_head PF00063.16 EGC29118.1 - 2.7e-182 607.4 18.6 1.4e-160 535.6 7.7 2.1 1 1 1 2 2 2 2 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC29118.1 - 1.9e-26 92.6 2.5 1.9e-26 92.6 1.8 1.8 2 0 0 2 2 2 1 Myosin tail IQ PF00612.22 EGC29118.1 - 7e-06 25.2 5.6 0.0001 21.5 0.9 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EGC29118.1 - 0.0056 16.8 0.0 0.027 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGC29118.1 - 0.077 11.8 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein PCI PF01399.22 EGC29119.1 - 1.9e-05 24.8 4.2 8e-05 22.9 1.5 3.3 2 0 0 2 2 2 1 PCI domain NSP2-B_epitope PF14757.1 EGC29119.1 - 1.1 8.6 3.9 2 7.8 2.7 1.3 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein FNIP PF05725.7 EGC29120.1 - 0.0002 21.2 2.6 0.00042 20.2 1.1 2.0 2 0 0 2 2 2 1 FNIP Repeat SAM_1 PF00536.25 EGC29121.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC29121.1 - 0.061 13.1 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) DUF4264 PF14084.1 EGC29122.1 - 0.0056 16.0 0.1 0.07 12.5 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4264) TFIIF_alpha PF05793.7 EGC29123.1 - 0.0032 15.8 49.2 0.0043 15.4 34.1 1.1 1 0 0 1 1 1 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) TIG PF01833.19 EGC29125.1 - 3.1e-11 43.0 9.2 0.00014 21.7 0.1 3.3 2 1 1 3 3 3 3 IPT/TIG domain Snf7 PF03357.16 EGC29126.1 - 6.1e-05 22.4 3.5 6.1e-05 22.4 2.4 1.8 1 1 1 2 2 2 1 Snf7 FAD-oxidase_C PF02913.14 EGC29126.1 - 0.13 11.5 0.0 0.15 11.3 0.0 1.0 1 0 0 1 1 1 0 FAD linked oxidases, C-terminal domain YbaB_DNA_bd PF02575.11 EGC29126.1 - 0.4 10.6 2.0 0.27 11.1 0.4 1.5 2 0 0 2 2 2 0 YbaB/EbfC DNA-binding family Reo_sigmaC PF04582.7 EGC29127.1 - 7.5e-08 31.9 9.2 1.1e-05 24.8 0.9 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein Bacillus_HBL PF05791.6 EGC29127.1 - 3.8e-06 26.3 16.2 3.8e-06 26.3 11.2 2.8 1 1 1 3 3 3 2 Bacillus haemolytic enterotoxin (HBL) WEMBL PF05701.6 EGC29127.1 - 6.9e-06 24.8 24.9 0.0011 17.5 7.0 2.1 1 1 0 2 2 2 2 Weak chloroplast movement under blue light AAA_13 PF13166.1 EGC29127.1 - 8.2e-06 24.5 13.4 8.2e-06 24.5 9.3 2.4 1 1 1 2 2 2 2 AAA domain IncA PF04156.9 EGC29127.1 - 5.2e-05 22.9 18.9 5.2e-05 22.9 13.1 2.6 1 1 1 2 2 2 1 IncA protein Baculo_PEP_C PF04513.7 EGC29127.1 - 8.4e-05 22.4 17.3 0.023 14.4 4.6 2.9 1 1 2 3 3 3 2 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EGC29127.1 - 0.00029 20.5 23.6 0.0029 17.3 6.2 2.7 1 1 1 2 2 2 2 Laminin Domain II LOH1CR12 PF10158.4 EGC29127.1 - 0.00051 19.8 12.9 0.024 14.4 1.8 2.7 1 1 1 2 2 2 2 Tumour suppressor protein DivIVA PF05103.8 EGC29127.1 - 0.00057 19.9 29.0 0.0017 18.4 3.6 3.7 2 2 1 3 3 3 1 DivIVA protein GAS PF13851.1 EGC29127.1 - 0.0011 18.1 38.2 0.0048 16.1 19.2 2.7 1 1 1 2 2 2 1 Growth-arrest specific micro-tubule binding TMF_DNA_bd PF12329.3 EGC29127.1 - 0.0012 18.5 9.0 0.0012 18.5 6.2 4.5 3 2 2 5 5 4 1 TATA element modulatory factor 1 DNA binding ADIP PF11559.3 EGC29127.1 - 0.0023 17.8 29.1 0.017 15.0 6.9 3.2 2 2 1 3 3 3 2 Afadin- and alpha -actinin-Binding DUF3584 PF12128.3 EGC29127.1 - 0.0026 15.2 24.0 0.0035 14.7 16.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) DASH_Dad1 PF08649.5 EGC29127.1 - 0.0032 17.1 0.6 0.0032 17.1 0.4 3.3 3 0 0 3 3 3 1 DASH complex subunit Dad1 Fib_alpha PF08702.5 EGC29127.1 - 0.0074 16.4 30.6 0.13 12.4 6.8 2.8 1 1 1 2 2 2 2 Fibrinogen alpha/beta chain family DUF4200 PF13863.1 EGC29127.1 - 0.0092 15.9 14.8 0.0092 15.9 10.3 3.7 2 1 2 4 4 4 1 Domain of unknown function (DUF4200) UBN_AB PF14075.1 EGC29127.1 - 0.0096 15.6 6.9 0.0096 15.6 4.8 2.7 1 1 2 3 3 3 1 Ubinuclein conserved middle domain Syntaxin_2 PF14523.1 EGC29127.1 - 0.014 15.4 8.3 0.014 15.4 5.8 3.9 1 1 2 3 3 3 0 Syntaxin-like protein DUF1664 PF07889.7 EGC29127.1 - 0.017 14.9 21.1 0.032 14.0 2.9 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) HrpB7 PF09486.5 EGC29127.1 - 0.02 14.8 7.0 0.07 13.0 2.0 2.7 1 1 2 3 3 2 0 Bacterial type III secretion protein (HrpB7) DUF3452 PF11934.3 EGC29127.1 - 0.02 14.2 6.0 0.1 11.9 4.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) NPV_P10 PF05531.7 EGC29127.1 - 0.021 15.0 23.9 0.51 10.6 1.8 4.3 2 2 2 4 4 4 0 Nucleopolyhedrovirus P10 protein MCPsignal PF00015.16 EGC29127.1 - 0.024 14.1 14.3 0.078 12.5 3.1 2.6 1 1 2 3 3 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Myosin_tail_1 PF01576.14 EGC29127.1 - 0.028 12.1 30.9 0.017 12.9 7.2 1.9 1 1 1 2 2 2 0 Myosin tail DUF4527 PF15030.1 EGC29127.1 - 0.028 13.7 1.8 0.051 12.8 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4527) Prefoldin PF02996.12 EGC29127.1 - 0.045 13.4 27.2 0.078 12.6 1.9 4.7 2 2 1 4 4 4 0 Prefoldin subunit FH2 PF02181.18 EGC29127.1 - 0.057 12.3 19.3 0.19 10.5 5.2 3.0 1 1 2 3 3 3 0 Formin Homology 2 Domain DUF4315 PF14193.1 EGC29127.1 - 0.059 13.3 1.1 0.059 13.3 0.8 5.0 1 1 3 5 5 5 0 Domain of unknown function (DUF4315) Mnd1 PF03962.10 EGC29127.1 - 0.061 12.9 27.4 0.19 11.4 7.0 2.6 1 1 1 2 2 2 0 Mnd1 family Spc7 PF08317.6 EGC29127.1 - 0.064 11.9 35.6 0.89 8.1 7.4 3.1 1 1 2 3 3 3 0 Spc7 kinetochore protein PilJ PF13675.1 EGC29127.1 - 0.064 13.5 8.2 0.68 10.2 2.2 3.3 1 1 3 4 4 4 0 Type IV pili methyl-accepting chemotaxis transducer N-term ERM PF00769.14 EGC29127.1 - 0.074 12.5 24.5 0.05 13.1 5.6 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family PspA_IM30 PF04012.7 EGC29127.1 - 0.087 12.1 16.8 0.69 9.2 11.5 2.8 1 1 0 1 1 1 0 PspA/IM30 family DUF641 PF04859.7 EGC29127.1 - 0.095 12.4 15.7 0.5 10.1 1.5 3.6 1 1 2 3 3 3 0 Plant protein of unknown function (DUF641) APG17 PF04108.7 EGC29127.1 - 0.099 11.4 21.2 0.74 8.5 14.7 2.2 1 1 0 1 1 1 0 Autophagy protein Apg17 Cast PF10174.4 EGC29127.1 - 0.11 10.5 29.2 0.61 8.0 19.7 1.9 1 1 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone HsbA PF12296.3 EGC29127.1 - 0.11 12.3 11.2 0.39 10.5 0.6 3.2 2 1 1 4 4 3 0 Hydrophobic surface binding protein A TPR_MLP1_2 PF07926.7 EGC29127.1 - 0.13 11.9 31.9 1.5 8.5 18.5 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein CENP-F_leu_zip PF10473.4 EGC29127.1 - 0.13 12.0 27.6 0.72 9.7 1.6 3.9 1 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 COG2 PF06148.6 EGC29127.1 - 0.15 11.8 16.0 2.2 8.1 3.6 3.6 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF812 PF05667.6 EGC29127.1 - 0.17 10.3 27.0 0.23 9.9 14.9 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF812) MRFAP1 PF15155.1 EGC29127.1 - 0.18 12.1 2.2 0.73 10.1 0.9 2.2 1 1 1 2 2 2 0 MORF4 family-associated protein1 Filament PF00038.16 EGC29127.1 - 0.19 11.1 28.8 3.1 7.1 19.9 2.9 1 1 0 1 1 1 0 Intermediate filament protein Uds1 PF15456.1 EGC29127.1 - 0.21 11.5 16.1 0.21 11.5 3.8 2.7 1 1 1 2 2 2 0 Up-regulated During Septation APG6 PF04111.7 EGC29127.1 - 0.22 10.5 29.9 0.22 10.5 9.0 2.5 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF4349 PF14257.1 EGC29127.1 - 0.24 10.5 9.3 2.5 7.2 1.8 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF4349) XFP_C PF09363.5 EGC29127.1 - 0.28 10.5 3.9 3.8 6.8 0.1 2.5 2 0 0 2 2 2 0 XFP C-terminal domain Spectrin PF00435.16 EGC29127.1 - 0.35 11.1 20.5 0.091 13.0 5.3 3.7 1 1 3 4 4 4 0 Spectrin repeat DUF4140 PF13600.1 EGC29127.1 - 0.36 11.2 15.7 0.98 9.9 1.8 3.9 2 2 2 4 4 4 0 N-terminal domain of unknown function (DUF4140) MscS_porin PF12795.2 EGC29127.1 - 0.41 9.9 30.0 0.67 9.2 8.2 2.4 1 1 1 2 2 2 0 Mechanosensitive ion channel porin domain Syntaxin-6_N PF09177.6 EGC29127.1 - 0.51 10.7 21.1 0.19 12.1 2.9 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal SlyX PF04102.7 EGC29127.1 - 0.55 10.6 16.2 1.2 9.5 2.2 3.9 1 1 3 4 4 4 0 SlyX LPP PF04728.8 EGC29127.1 - 0.6 9.9 8.8 1.7 8.4 0.1 3.8 3 1 0 3 3 2 0 Lipoprotein leucine-zipper DUF948 PF06103.6 EGC29127.1 - 0.62 9.9 13.9 0.53 10.1 1.3 3.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) WXG100 PF06013.7 EGC29127.1 - 0.65 10.0 9.0 25 4.9 0.0 4.0 1 1 2 3 3 3 0 Proteins of 100 residues with WXG DUF4201 PF13870.1 EGC29127.1 - 0.67 9.3 35.1 0.45 9.9 11.0 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) Cytochrom_C_2 PF01322.15 EGC29127.1 - 0.67 10.4 4.6 15 6.1 0.4 2.6 1 1 1 2 2 2 0 Cytochrome C' DUF869 PF05911.6 EGC29127.1 - 0.68 8.0 27.2 6.7 4.8 18.4 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF869) Prefoldin_2 PF01920.15 EGC29127.1 - 0.72 9.6 34.2 4 7.2 3.9 5.1 2 2 0 3 3 3 0 Prefoldin subunit DUF3450 PF11932.3 EGC29127.1 - 0.84 8.8 26.0 0.08 12.1 4.2 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF3450) DUF2443 PF10398.4 EGC29127.1 - 0.91 9.3 16.8 0.25 11.1 0.2 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF2443) Tropomyosin PF00261.15 EGC29127.1 - 0.97 8.4 29.6 0.7 8.9 8.3 3.1 2 2 1 3 3 3 0 Tropomyosin AATF-Che1 PF13339.1 EGC29127.1 - 1 9.5 17.8 0.039 14.1 4.1 2.7 1 1 1 2 2 2 0 Apoptosis antagonizing transcription factor Prominin PF05478.6 EGC29127.1 - 1 6.8 18.6 0.38 8.2 10.4 1.8 1 1 1 2 2 2 0 Prominin DUF4407 PF14362.1 EGC29127.1 - 1 8.2 16.9 5.9 5.7 11.7 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4407) DUF2670 PF10875.3 EGC29127.1 - 1.1 9.3 5.2 0.33 10.9 0.8 2.2 2 1 1 3 3 1 0 Protein of unknown function (DUF2670) Seryl_tRNA_N PF02403.17 EGC29127.1 - 1.1 9.3 34.9 1.4 9.0 8.6 3.7 1 1 2 3 3 3 0 Seryl-tRNA synthetase N-terminal domain Surfac_D-trimer PF09006.6 EGC29127.1 - 1.2 8.9 4.0 31 4.3 0.2 3.8 4 0 0 4 4 3 0 Lung surfactant protein D coiled-coil trimerisation DUF2968 PF11180.3 EGC29127.1 - 1.2 8.5 17.0 0.37 10.1 4.2 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) DUF4298 PF14131.1 EGC29127.1 - 1.2 9.0 12.3 4.4 7.2 0.9 3.8 2 1 0 3 3 3 0 Domain of unknown function (DUF4298) CCDC155 PF14662.1 EGC29127.1 - 1.4 8.4 27.9 0.41 10.2 13.8 2.7 1 1 2 3 3 3 0 Coiled-coil region of CCDC155 H-kinase_dim PF02895.9 EGC29127.1 - 1.4 9.2 12.2 15 5.9 8.5 2.8 1 1 0 1 1 1 0 Signal transducing histidine kinase, homodimeric domain Ndc1_Nup PF09531.5 EGC29127.1 - 1.4 7.2 5.9 1.7 6.9 4.1 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Atg14 PF10186.4 EGC29127.1 - 1.6 7.6 30.1 0.35 9.7 6.4 2.9 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 Occludin_ELL PF07303.8 EGC29127.1 - 1.6 9.5 19.1 0.076 13.7 3.0 3.8 1 1 3 4 4 4 0 Occludin homology domain Med4 PF10018.4 EGC29127.1 - 1.7 7.9 15.4 4.2 6.7 3.4 2.6 1 1 1 2 2 2 0 Vitamin-D-receptor interacting Mediator subunit 4 Alpha-2-MRAP_C PF06401.6 EGC29127.1 - 1.9 8.2 25.8 6.8 6.4 3.9 3.2 1 1 1 2 2 2 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF972 PF06156.8 EGC29127.1 - 2.2 8.6 26.0 2.4 8.5 3.0 3.8 1 1 3 4 4 4 0 Protein of unknown function (DUF972) MbeD_MobD PF04899.7 EGC29127.1 - 2.3 8.1 7.1 4.1 7.3 2.8 2.9 3 1 1 4 4 2 0 MbeD/MobD like TMPIT PF07851.8 EGC29127.1 - 2.4 7.1 21.0 0.6 9.1 6.2 2.5 1 1 2 3 3 3 0 TMPIT-like protein Cep57_CLD_2 PF14197.1 EGC29127.1 - 2.4 8.1 19.8 0.89 9.5 4.6 3.7 1 1 2 3 3 3 0 Centrosome localisation domain of PPC89 COG5 PF10392.4 EGC29127.1 - 2.6 7.9 17.1 2.4 8.1 1.9 3.6 2 2 1 3 3 3 0 Golgi transport complex subunit 5 ATG16 PF08614.6 EGC29127.1 - 2.7 7.7 31.0 0.06 13.1 7.7 3.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Snapin_Pallidin PF14712.1 EGC29127.1 - 3.6 7.9 25.3 7 7.0 4.3 4.2 1 1 3 4 4 4 0 Snapin/Pallidin IFT57 PF10498.4 EGC29127.1 - 3.9 6.1 31.2 0.19 10.4 8.3 2.2 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Spc24 PF08286.6 EGC29127.1 - 4 7.1 32.2 1.4 8.6 2.6 4.2 1 1 3 4 4 4 0 Spc24 subunit of Ndc80 DUF4164 PF13747.1 EGC29127.1 - 4.1 7.6 20.8 0.18 11.9 4.3 3.5 1 1 3 4 4 4 0 Domain of unknown function (DUF4164) Cob_adeno_trans PF01923.13 EGC29127.1 - 4.1 7.1 13.6 5.4 6.7 3.4 2.8 1 1 1 2 2 2 0 Cobalamin adenosyltransferase Tropomyosin_1 PF12718.2 EGC29127.1 - 4.6 7.0 33.2 0.46 10.3 8.7 2.5 1 1 1 2 2 2 0 Tropomyosin like Glycohydro_20b2 PF14845.1 EGC29127.1 - 5.2 7.7 7.1 28 5.3 4.9 2.1 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like bZIP_1 PF00170.16 EGC29127.1 - 5.7 6.9 18.7 0.19 11.6 1.0 4.3 3 1 1 4 4 3 0 bZIP transcription factor Zein-binding PF04576.10 EGC29127.1 - 6.1 7.0 15.1 3.5 7.8 2.8 3.8 1 1 3 4 4 4 0 Zein-binding Cluap1 PF10234.4 EGC29127.1 - 6.2 5.9 26.5 7.4 5.6 8.4 3.4 1 1 2 3 3 3 0 Clusterin-associated protein-1 Adeno_PIX PF03955.9 EGC29127.1 - 7.2 7.1 7.6 14 6.2 0.3 3.0 1 1 1 3 3 2 0 Adenovirus hexon-associated protein (IX) DivIC PF04977.10 EGC29127.1 - 8.4 5.9 36.5 0.38 10.2 1.9 5.3 2 2 3 5 5 5 0 Septum formation initiator FemAB PF02388.11 EGC29127.1 - 8.9 4.8 18.3 0.62 8.6 4.5 2.4 1 1 1 2 2 2 0 FemAB family MerR-DNA-bind PF09278.6 EGC29127.1 - 9.2 6.7 7.7 18 5.7 2.0 3.6 3 2 1 4 4 2 0 MerR, DNA binding Terpene_synth_C PF03936.11 EGC29128.1 - 1.8e-08 33.9 0.4 2.9e-08 33.2 0.3 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Fz PF01392.17 EGC29129.1 - 0.011 16.1 0.6 0.021 15.1 0.4 1.4 1 0 0 1 1 1 0 Fz domain SBF2 PF12335.3 EGC29129.1 - 0.14 11.4 0.1 0.23 10.7 0.1 1.2 1 0 0 1 1 1 0 Myotubularin protein Saccharop_dh PF03435.13 EGC29130.1 - 8.5e-82 275.1 0.0 1.1e-81 274.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase AlaDh_PNT_N PF05222.10 EGC29130.1 - 5.7e-27 94.3 0.0 1.2e-26 93.3 0.0 1.6 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain AlaDh_PNT_C PF01262.16 EGC29130.1 - 1.4e-24 86.5 0.0 5.5e-24 84.6 0.0 2.0 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain TrkA_N PF02254.13 EGC29130.1 - 2.1e-05 24.5 0.1 4.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_10 PF13460.1 EGC29130.1 - 0.0068 16.4 0.0 0.014 15.4 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding ThiF PF00899.16 EGC29130.1 - 0.092 12.5 1.2 15 5.4 0.1 3.2 3 0 0 3 3 3 0 ThiF family Shikimate_DH PF01488.15 EGC29130.1 - 0.097 12.7 0.1 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase His_Phos_2 PF00328.17 EGC29131.1 - 1.1e-26 94.0 0.5 1.4e-26 93.6 0.4 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) OTU PF02338.14 EGC29132.1 - 8.2e-13 49.0 0.1 8.2e-13 49.0 0.1 2.9 2 1 0 2 2 2 1 OTU-like cysteine protease TrmB PF01978.14 EGC29133.1 - 0.14 11.9 0.1 0.15 11.7 0.1 1.1 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Macoilin PF09726.4 EGC29134.1 - 1.5 6.9 5.9 1.6 6.9 4.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF892 PF05974.7 EGC29135.1 - 0.033 13.9 0.4 1.2 8.8 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF892) Talin_middle PF09141.5 EGC29135.1 - 0.094 12.3 0.1 0.15 11.7 0.0 1.4 1 1 0 1 1 1 0 Talin, middle domain LPAM_2 PF13627.1 EGC29136.1 - 2.8 7.7 4.3 5 6.9 3.0 1.4 1 0 0 1 1 1 0 Prokaryotic lipoprotein-attachment site TMEM151 PF14857.1 EGC29138.1 - 0.0047 15.5 2.3 0.006 15.2 1.6 1.1 1 0 0 1 1 1 1 TMEM151 family TPR_1 PF00515.23 EGC29139.1 - 3.8e-15 54.7 7.9 5.5e-07 28.9 0.2 3.8 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC29139.1 - 2.3e-14 52.7 1.2 2.3e-14 52.7 0.8 1.9 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGC29139.1 - 2.9e-12 45.4 5.7 1.3e-05 24.7 0.1 3.6 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC29139.1 - 1.5e-08 35.0 0.1 3.1e-08 34.0 0.1 1.5 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC29139.1 - 1.9e-08 34.0 1.5 3.1e-07 30.2 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29139.1 - 3.7e-08 32.5 13.9 0.00015 21.2 0.2 4.8 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC29139.1 - 5.3e-07 28.9 0.8 0.0076 15.9 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC29139.1 - 1.3e-05 25.3 0.1 0.094 13.3 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC29139.1 - 1.4e-05 25.3 1.0 3.7e-05 23.9 0.7 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC29139.1 - 0.00084 19.3 0.8 0.00084 19.3 0.5 3.9 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC29139.1 - 0.0011 19.0 0.4 0.0088 16.1 0.5 2.4 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 MIT PF04212.13 EGC29139.1 - 0.0056 16.5 0.5 0.0056 16.5 0.3 2.5 3 0 0 3 3 3 1 MIT (microtubule interacting and transport) domain TPR_9 PF13371.1 EGC29139.1 - 0.012 15.4 0.0 0.026 14.3 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC29139.1 - 0.099 12.6 1.5 29 4.7 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC29139.1 - 0.1 13.1 1.4 8.4 7.0 0.1 3.1 2 0 0 2 2 2 0 Tetratricopeptide repeat PPR PF01535.15 EGC29139.1 - 0.12 12.4 0.6 0.93 9.6 0.1 2.5 2 0 0 2 2 2 0 PPR repeat ELYS PF13934.1 EGC29140.1 - 2.5e-18 66.6 1.8 2.5e-18 66.6 1.2 2.4 2 0 0 2 2 2 1 Nuclear pore complex assembly Membrane_bind PF14564.1 EGC29141.1 - 9e-28 96.6 0.6 1e-27 96.4 0.4 1.0 1 0 0 1 1 1 1 Membrane binding PSI PF01437.20 EGC29142.1 - 8.7e-06 25.7 10.0 2e-05 24.6 6.9 1.6 1 0 0 1 1 1 1 Plexin repeat Rhabdo_glycop PF00974.13 EGC29142.1 - 0.0013 17.1 0.8 0.0024 16.1 0.5 1.4 1 0 0 1 1 1 1 Rhabdovirus spike glycoprotein Baculo_11_kDa PF06143.6 EGC29142.1 - 0.0016 17.7 0.3 0.37 10.1 0.1 2.3 2 0 0 2 2 2 1 Baculovirus 11 kDa family EphA2_TM PF14575.1 EGC29142.1 - 0.0042 17.4 0.0 0.15 12.4 0.0 2.3 2 0 0 2 2 2 1 Ephrin type-A receptor 2 transmembrane domain Protocadherin PF08374.6 EGC29142.1 - 0.0066 16.1 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Protocadherin gpUL132 PF11359.3 EGC29142.1 - 0.01 15.1 0.0 0.01 15.1 0.0 2.1 2 0 0 2 2 2 0 Glycoprotein UL132 DUF3169 PF11368.3 EGC29142.1 - 0.027 13.6 0.5 4.4 6.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3169) IncA PF04156.9 EGC29142.1 - 0.027 14.0 0.0 0.093 12.3 0.0 1.7 2 0 0 2 2 2 0 IncA protein CMV_US PF08001.6 EGC29142.1 - 0.053 12.5 0.1 0.11 11.5 0.0 1.5 2 0 0 2 2 2 0 CMV US TMEM154 PF15102.1 EGC29142.1 - 0.055 13.1 2.0 0.18 11.5 1.3 1.9 1 1 0 1 1 1 0 TMEM154 protein family ATP-synt_8 PF00895.15 EGC29142.1 - 0.061 13.5 0.8 8.2 6.7 0.2 2.4 2 0 0 2 2 2 0 ATP synthase protein 8 Prominin PF05478.6 EGC29142.1 - 0.081 10.4 5.2 0.11 10.0 3.6 1.2 1 0 0 1 1 1 0 Prominin Shisa PF13908.1 EGC29142.1 - 0.59 10.2 13.8 0.27 11.4 7.9 1.7 1 1 1 2 2 2 0 Wnt and FGF inhibitory regulator Orthoreo_P10 PF07204.6 EGC29142.1 - 3.7 7.3 9.8 1 9.1 4.6 1.9 1 1 1 2 2 2 0 Orthoreovirus membrane fusion protein p10 RCR PF12273.3 EGC29142.1 - 4.5 7.8 8.5 9.9 6.7 5.1 2.2 2 1 0 2 2 2 0 Chitin synthesis regulation, resistance to Congo red GATA PF00320.22 EGC29143.1 - 5.4e-14 51.2 6.1 1.2e-13 50.1 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EGC29143.1 - 0.57 10.2 3.2 1.2 9.1 2.2 1.6 1 0 0 1 1 1 0 zinc-finger Mucin PF01456.12 EGC29143.1 - 5.9 6.6 14.9 1.2 8.9 5.9 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Rad60-SLD PF11976.3 EGC29144.1 - 9.1e-05 22.0 2.9 0.00026 20.6 0.0 3.1 3 0 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like Nop14 PF04147.7 EGC29146.1 - 0.1 10.5 44.4 0.19 9.5 30.8 1.6 1 0 0 1 1 1 0 Nop14-like family CENP-T PF15511.1 EGC29146.1 - 2 7.6 25.9 3.7 6.6 17.9 1.4 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T COX7C PF02935.11 EGC29149.1 - 0.00037 20.2 2.3 0.0014 18.3 1.6 1.9 1 1 0 1 1 1 1 Cytochrome c oxidase subunit VIIc Fe-ADH PF00465.14 EGC29151.1 - 5.7e-56 189.7 0.0 6.9e-56 189.4 0.0 1.1 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase Fe-ADH_2 PF13685.1 EGC29151.1 - 5.6e-33 114.2 0.0 7.5e-33 113.8 0.0 1.2 1 0 0 1 1 1 1 Iron-containing alcohol dehydrogenase DHQ_synthase PF01761.15 EGC29151.1 - 1.6e-06 27.2 0.3 5.3e-05 22.2 0.1 3.0 1 1 1 2 2 2 1 3-dehydroquinate synthase DUF1341 PF07071.6 EGC29151.1 - 0.0049 16.4 0.1 3.1 7.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1341) TINF2_N PF14973.1 EGC29151.1 - 0.16 12.1 0.5 2.5 8.2 0.0 2.2 2 0 0 2 2 2 0 TERF1-interacting nuclear factor 2 N-terminus tRNA-synt_1c PF00749.16 EGC29152.1 - 1e-111 372.6 0.0 1.5e-111 372.0 0.0 1.3 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain PAH PF02671.16 EGC29152.1 - 0.015 14.8 0.1 0.047 13.3 0.1 2.0 1 0 0 1 1 1 0 Paired amphipathic helix repeat tRNA-synt_1d PF00750.14 EGC29152.1 - 0.036 12.8 0.0 0.52 9.0 0.0 2.7 3 0 0 3 3 3 0 tRNA synthetases class I (R) CobT PF06213.7 EGC29153.1 - 0.37 9.8 18.1 0.5 9.4 12.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Utp11 PF03998.8 EGC29153.1 - 0.98 9.1 12.1 1.2 8.9 8.4 1.1 1 0 0 1 1 1 0 Utp11 protein UQ_con PF00179.21 EGC29154.1 - 1.5e-51 173.5 0.2 1.7e-51 173.3 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGC29154.1 - 0.032 14.1 0.4 0.061 13.2 0.2 1.6 1 1 0 2 2 2 0 RWD domain Rrp15p PF07890.7 EGC29155.1 - 8.2e-22 77.6 11.7 8.2e-22 77.6 8.1 1.9 2 0 0 2 2 2 1 Rrp15p DUF1788 PF08747.6 EGC29155.1 - 4.2 7.2 5.7 3.6 7.4 1.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1788) Peptidase_C14 PF00656.17 EGC29156.1 - 0.088 12.4 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 Caspase domain HTH_Tnp_4 PF13613.1 EGC29157.1 - 0.006 16.0 0.0 0.012 15.1 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Phosphorylase PF00343.15 EGC29158.1 - 0 1185.2 1.7 0 1185.0 1.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Sod_Cu PF00080.15 EGC29159.1 - 1.6e-46 157.9 7.8 1.9e-46 157.7 5.4 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) Nucleoside_tran PF01733.13 EGC29160.1 - 1.2e-29 103.4 13.0 1.2e-29 103.4 9.0 1.8 1 1 0 2 2 2 1 Nucleoside transporter MFS_1 PF07690.11 EGC29160.1 - 9e-08 31.2 24.4 1.8e-07 30.2 3.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4179 PF13786.1 EGC29160.1 - 0.47 10.7 0.1 0.47 10.7 0.1 3.9 4 1 0 4 4 4 0 Domain of unknown function (DUF4179) Nucleoside_tran PF01733.13 EGC29161.1 - 1.9e-34 119.2 17.0 1.9e-34 119.2 11.8 2.3 2 0 0 2 2 2 1 Nucleoside transporter Sec34 PF04136.10 EGC29162.1 - 8.5e-25 87.2 5.1 8.5e-25 87.2 3.6 3.5 4 0 0 4 4 4 1 Sec34-like family PP2C_C PF07830.8 EGC29162.1 - 0.3 11.2 2.2 6.8 6.8 0.0 3.4 3 0 0 3 3 3 0 Protein serine/threonine phosphatase 2C, C-terminal domain Sod_Cu PF00080.15 EGC29163.1 - 3.9e-27 95.1 0.0 4.7e-27 94.8 0.0 1.1 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF3595 PF12166.3 EGC29164.1 - 2.1e-94 316.7 4.6 2.1e-94 316.7 3.2 4.8 5 0 0 5 5 5 1 Protein of unknown function (DUF3595) PHD PF00628.24 EGC29166.1 - 1.2e-10 40.9 6.0 2.8e-10 39.7 4.1 1.7 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H PF13771.1 EGC29166.1 - 0.00079 19.5 1.2 0.00079 19.5 0.8 2.6 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EGC29166.1 - 0.0078 15.5 2.0 0.0078 15.5 1.4 1.9 2 0 0 2 2 2 1 PHD-finger zf-C4_ClpX PF06689.8 EGC29166.1 - 0.5 9.9 6.8 0.57 9.7 1.2 2.9 2 0 0 2 2 2 0 ClpX C4-type zinc finger Daxx PF03344.10 EGC29166.1 - 4.8 5.5 37.4 8 4.8 25.9 1.3 1 0 0 1 1 1 0 Daxx Family Homeobox PF00046.24 EGC29167.1 - 3e-19 68.3 4.2 5.9e-19 67.4 2.9 1.5 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGC29167.1 - 0.0031 17.2 1.5 0.0054 16.4 0.1 2.2 2 0 0 2 2 2 1 Homeobox KN domain HCaRG PF07258.9 EGC29168.1 - 1.8e-35 122.0 4.6 2.1e-35 121.8 3.2 1.0 1 0 0 1 1 1 1 HCaRG protein CCT_2 PF09425.5 EGC29169.1 - 0.12 11.9 0.1 0.23 11.0 0.1 1.5 1 0 0 1 1 1 0 Divergent CCT motif PAT1 PF09770.4 EGC29169.1 - 0.19 9.9 29.3 0.14 10.3 4.0 2.2 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 Dicty_REP PF05086.7 EGC29169.1 - 0.56 7.8 21.3 0.72 7.5 10.2 2.2 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein XhlA PF10779.4 EGC29170.1 - 0.084 12.7 5.9 1.2 9.0 0.1 3.1 2 0 0 2 2 2 0 Haemolysin XhlA RrnaAD PF00398.15 EGC29171.1 - 4.7e-61 206.1 0.0 5.8e-61 205.8 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_26 PF13659.1 EGC29171.1 - 1.4e-12 47.6 0.0 2e-12 47.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29171.1 - 9e-07 29.4 0.0 1.3e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29171.1 - 6.7e-06 25.7 0.0 1.1e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29171.1 - 3.5e-05 24.2 0.0 7.9e-05 23.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC29171.1 - 6.1e-05 22.2 0.0 0.0001 21.4 0.0 1.4 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGC29171.1 - 0.00019 20.8 0.0 0.0003 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain PCMT PF01135.14 EGC29171.1 - 0.0002 20.9 0.0 0.00029 20.4 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_11 PF08241.7 EGC29171.1 - 0.00029 21.2 0.0 0.00063 20.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29171.1 - 0.00047 19.9 0.0 0.00073 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain NodS PF05401.6 EGC29171.1 - 0.00082 18.8 0.0 0.0015 17.9 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 EGC29171.1 - 0.0021 18.4 0.0 0.0039 17.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC29171.1 - 0.0025 16.9 0.0 0.0038 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase DREV PF05219.7 EGC29171.1 - 0.0045 15.8 0.0 0.009 14.9 0.0 1.4 1 0 0 1 1 1 1 DREV methyltransferase Ubie_methyltran PF01209.13 EGC29171.1 - 0.0088 15.1 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family DOT1 PF08123.8 EGC29171.1 - 0.011 15.0 0.0 0.019 14.2 0.0 1.3 1 0 0 1 1 1 0 Histone methylation protein DOT1 Met_10 PF02475.11 EGC29171.1 - 0.044 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein tRNA_U5-meth_tr PF05958.6 EGC29171.1 - 0.047 12.3 0.0 0.065 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA (Uracil-5-)-methyltransferase Zn_ribbon_2 PF12674.2 EGC29171.1 - 0.071 13.4 0.1 0.17 12.2 0.1 1.6 1 0 0 1 1 1 0 Putative zinc ribbon domain Methyltransf_32 PF13679.1 EGC29171.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MFS_1 PF07690.11 EGC29173.1 - 3.1e-51 174.1 44.4 1.3e-49 168.8 32.8 2.0 2 0 0 2 2 2 1 Major Facilitator Superfamily TRI12 PF06609.8 EGC29173.1 - 3.8e-23 81.5 30.6 5.5e-23 81.0 21.2 1.1 1 0 0 1 1 1 1 Fungal trichothecene efflux pump (TRI12) Sugar_tr PF00083.19 EGC29173.1 - 6.5e-14 51.3 14.1 6.5e-14 51.3 9.8 2.8 3 0 0 3 3 3 1 Sugar (and other) transporter DUF2547 PF10818.3 EGC29174.1 - 0.024 15.2 3.4 0.15 12.6 2.3 2.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) Robl_LC7 PF03259.12 EGC29176.1 - 7.3e-08 31.8 0.0 7.6e-08 31.8 0.0 1.0 1 0 0 1 1 1 1 Roadblock/LC7 domain WASH-7_N PF14745.1 EGC29177.1 - 2.3e-210 699.5 15.0 2.3e-210 699.5 10.4 1.6 2 0 0 2 2 2 1 WASH complex subunit 7, N-terminal WASH-7_mid PF14744.1 EGC29177.1 - 6.9e-153 508.6 8.6 2.1e-152 507.0 5.9 1.9 1 0 0 1 1 1 1 WASH complex subunit 7 WASH-7_C PF14746.1 EGC29177.1 - 1e-62 210.7 6.2 1e-62 210.7 4.3 2.1 2 0 0 2 2 2 1 WASH complex subunit 7, C-terminal Mating_N PF12731.2 EGC29177.1 - 0.024 14.4 0.6 0.089 12.6 0.0 2.2 2 0 0 2 2 2 0 Mating-type protein beta 1 DUF3095 PF11294.3 EGC29178.1 - 0.11 11.5 0.7 0.18 10.8 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3095) PCI PF01399.22 EGC29179.1 - 8.9e-21 74.1 2.0 1.5e-20 73.4 0.2 2.2 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGC29179.1 - 0.025 14.3 0.0 0.072 12.8 0.0 1.8 1 0 0 1 1 1 0 COP9 signalosome, subunit CSN8 CG-1 PF03859.11 EGC29179.1 - 0.042 13.3 0.7 0.098 12.1 0.5 1.7 1 1 0 1 1 1 0 CG-1 domain Pkinase PF00069.20 EGC29180.1 - 1e-78 264.1 0.0 1e-78 264.1 0.0 1.9 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29180.1 - 1.3e-44 152.2 0.0 4e-44 150.6 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGC29180.1 - 3.8e-18 64.6 0.1 6.6e-18 63.8 0.1 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EGC29180.1 - 9.5e-06 24.7 0.0 1.7e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC29180.1 - 0.00041 19.4 0.0 0.00088 18.3 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC29180.1 - 0.0029 17.3 0.0 0.012 15.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family UBA PF00627.26 EGC29180.1 - 0.0046 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 UBA/TS-N domain UBA_3 PF09288.5 EGC29180.1 - 0.15 11.6 1.9 0.24 11.0 0.0 2.3 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain Beta_helix PF13229.1 EGC29181.1 - 3.8e-36 124.2 80.4 2.4e-16 59.8 11.3 4.3 2 1 2 4 4 4 3 Right handed beta helix region NosD PF05048.8 EGC29181.1 - 7.2e-21 74.4 45.3 9e-14 51.1 19.1 4.0 2 1 1 3 3 3 2 Periplasmic copper-binding protein (NosD) F-box-like PF12937.2 EGC29181.1 - 1.8e-06 27.5 1.6 3.4e-06 26.6 1.1 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC29181.1 - 0.0015 18.1 0.8 0.0032 17.0 0.6 1.5 1 0 0 1 1 1 1 F-box domain Miff PF05644.6 EGC29181.1 - 2.8 7.4 14.1 6.4 6.3 9.8 1.6 1 1 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff F5_F8_type_C PF00754.20 EGC29182.1 - 6.4e-21 74.5 2.5 6.4e-21 74.5 1.7 1.7 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC29182.1 - 1.2e-19 69.7 0.0 2.4e-19 68.7 0.0 1.6 1 0 0 1 1 1 1 H-type lectin domain Adaptin_binding PF10199.4 EGC29183.1 - 2.6 8.3 10.0 5.3 7.3 6.9 1.8 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 Ribonuc_red_lgC PF02867.10 EGC29184.1 - 1.5e-10 40.2 0.1 0.0051 15.4 0.0 3.4 2 1 0 3 3 3 3 Ribonucleotide reductase, barrel domain cwf18 PF08315.7 EGC29185.1 - 1e-18 68.0 24.3 1e-18 68.0 16.9 2.9 1 1 1 2 2 2 1 cwf18 pre-mRNA splicing factor SAP PF02037.22 EGC29185.1 - 2.9e-05 23.4 1.6 6.9e-05 22.2 1.1 1.6 1 0 0 1 1 1 1 SAP domain DUF4045 PF13254.1 EGC29185.1 - 0.3 10.3 16.6 0.47 9.6 11.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Dapper PF15268.1 EGC29185.1 - 0.74 8.5 14.5 0.83 8.3 10.1 1.1 1 0 0 1 1 1 0 Dapper HgmA PF04209.8 EGC29187.1 - 4.3e-201 667.8 0.0 4.9e-201 667.6 0.0 1.0 1 0 0 1 1 1 1 homogentisate 1,2-dioxygenase Abhydrolase_3 PF07859.8 EGC29190.1 - 4.1e-63 212.7 1.8 6.3e-63 212.1 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold FYVE PF01363.16 EGC29190.1 - 1e-19 70.1 14.8 1.6e-19 69.5 8.2 2.4 2 0 0 2 2 2 1 FYVE zinc finger COesterase PF00135.23 EGC29190.1 - 4.5e-11 42.1 0.5 4.7e-10 38.7 0.0 2.3 2 0 0 2 2 2 1 Carboxylesterase family DUF2424 PF10340.4 EGC29190.1 - 3.6e-06 25.8 0.5 1e-05 24.3 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGC29190.1 - 0.0002 21.1 0.0 0.00049 19.8 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Spore_coat_CotO PF14153.1 EGC29190.1 - 0.0013 18.2 10.1 0.0018 17.7 7.0 1.2 1 0 0 1 1 1 1 Spore coat protein CotO Peptidase_S9 PF00326.16 EGC29190.1 - 0.015 14.4 0.0 0.043 13.0 0.0 1.8 1 0 0 1 1 1 0 Prolyl oligopeptidase family XAP5 PF04921.9 EGC29190.1 - 0.018 14.6 9.0 0.03 13.9 6.2 1.3 1 0 0 1 1 1 0 XAP5, circadian clock regulator FYVE_2 PF02318.11 EGC29190.1 - 0.031 14.1 10.0 0.095 12.6 6.9 1.9 1 0 0 1 1 1 0 FYVE-type zinc finger AXE1 PF05448.7 EGC29190.1 - 0.05 12.1 0.0 0.098 11.1 0.0 1.5 1 0 0 1 1 1 0 Acetyl xylan esterase (AXE1) Ycf1 PF05758.7 EGC29190.1 - 0.099 10.3 5.7 0.12 10.0 4.0 1.1 1 0 0 1 1 1 0 Ycf1 eIF-3_zeta PF05091.7 EGC29190.1 - 0.23 10.0 10.6 0.33 9.5 7.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Suf PF05843.9 EGC29190.1 - 0.43 10.2 14.9 0.62 9.7 10.3 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Esterase PF00756.15 EGC29190.1 - 1.4 8.3 6.2 9.6 5.5 0.0 2.8 3 0 0 3 3 3 0 Putative esterase Tim54 PF11711.3 EGC29190.1 - 1.7 7.1 9.9 2.7 6.4 6.9 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CDC45 PF02724.9 EGC29190.1 - 3.1 5.6 9.5 4.3 5.2 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein Pex14_N PF04695.8 EGC29190.1 - 4.2 7.4 17.8 9 6.3 12.4 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region AUX_IAA PF02309.11 EGC29190.1 - 4.6 6.9 14.6 7.8 6.1 10.1 1.2 1 0 0 1 1 1 0 AUX/IAA family zf-RING_5 PF14634.1 EGC29190.1 - 4.9 6.9 17.0 30 4.4 12.0 2.2 1 1 1 2 2 2 0 zinc-RING finger domain Dicty_REP PF05086.7 EGC29190.1 - 5.9 4.5 15.6 8.5 3.9 10.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Borrelia_P83 PF05262.6 EGC29190.1 - 7.8 4.6 11.7 11 4.1 8.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein PAT1 PF09770.4 EGC29190.1 - 8.5 4.4 23.1 11 4.0 16.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FKBP_C PF00254.23 EGC29191.1 - 1.4e-25 89.1 0.2 3.1e-20 71.9 0.0 2.7 2 0 0 2 2 2 2 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EGC29191.1 - 7.7e-09 35.0 4.4 1.8e-05 24.3 0.7 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC29191.1 - 1.1e-07 31.2 1.6 0.017 14.9 0.2 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC29191.1 - 9.1e-07 28.2 4.0 0.02 14.4 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat YhfZ_C PF14503.1 EGC29191.1 - 0.0085 15.4 1.8 0.019 14.3 0.4 2.1 2 0 0 2 2 2 1 YhfZ C-terminal domain TPR_12 PF13424.1 EGC29191.1 - 0.014 15.3 0.8 0.47 10.4 0.1 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC29191.1 - 0.034 14.3 0.7 0.51 10.6 0.0 3.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC29191.1 - 0.048 13.4 0.5 2.1 8.3 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29191.1 - 0.098 12.4 11.4 0.18 11.6 0.2 3.5 2 1 1 3 3 3 0 Tetratricopeptide repeat TP53IP5 PF15331.1 EGC29191.1 - 0.36 10.7 5.0 0.78 9.6 3.5 1.6 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 zf-RING_2 PF13639.1 EGC29192.1 - 1e-06 28.4 15.3 1.8e-06 27.6 10.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC29192.1 - 2.8e-05 24.1 9.3 7.9e-05 22.6 6.5 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC29192.1 - 0.00071 19.1 18.0 0.0015 18.1 12.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC29192.1 - 0.0016 18.0 13.9 0.0027 17.3 9.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29192.1 - 0.0016 18.3 17.7 0.0033 17.3 12.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) CTP_transf_3 PF02348.14 EGC29192.1 - 0.03 13.9 5.8 0.055 13.0 4.0 1.6 1 0 0 1 1 1 0 Cytidylyltransferase zf-RING_5 PF14634.1 EGC29192.1 - 0.098 12.4 16.9 0.19 11.5 11.7 1.5 1 0 0 1 1 1 0 zinc-RING finger domain 7tm_1 PF00001.16 EGC29192.1 - 0.65 9.0 3.4 10 5.1 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) DUF1049 PF06305.6 EGC29192.1 - 1.9 8.0 4.2 9.5 5.7 2.9 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1049) zf-C3HC4_4 PF15227.1 EGC29192.1 - 2.1 8.2 14.6 5.8 6.8 10.1 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING YjgP_YjgQ PF03739.9 EGC29192.1 - 2.7 6.6 4.4 1.6 7.4 0.7 2.0 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family Pkinase PF00069.20 EGC29193.1 - 1.5e-63 214.3 1.0 1.5e-63 214.3 0.7 2.1 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29193.1 - 1.7e-38 132.1 0.4 1.7e-38 132.1 0.2 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase SR-25 PF10500.4 EGC29193.1 - 0.011 15.2 21.9 0.017 14.5 0.7 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein APH PF01636.18 EGC29193.1 - 0.016 14.9 0.0 0.042 13.5 0.0 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family NHL PF01436.16 EGC29193.1 - 0.031 14.2 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 NHL repeat Mito_carr PF00153.22 EGC29195.1 - 0.0055 16.3 0.1 2.4 7.9 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein Abhydrolase_6 PF12697.2 EGC29196.1 - 6.2e-22 78.6 0.0 9.1e-22 78.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC29196.1 - 1.1e-11 44.6 0.0 1.9e-11 43.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC29196.1 - 2.5e-06 27.2 0.1 7.1e-05 22.4 0.1 2.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGC29196.1 - 2.9e-06 27.0 0.1 4.9e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EGC29196.1 - 0.00012 21.7 0.1 0.00039 20.0 0.1 2.0 1 1 0 1 1 1 1 Lipase (class 3) Abhydrolase_2 PF02230.11 EGC29196.1 - 0.0019 17.7 0.1 0.028 13.8 0.1 2.2 1 1 0 1 1 1 1 Phospholipase/Carboxylesterase Hydrolase_4 PF12146.3 EGC29196.1 - 0.0028 17.4 0.0 0.013 15.2 0.0 2.1 2 0 0 2 2 2 1 Putative lysophospholipase DUF676 PF05057.9 EGC29196.1 - 0.0033 16.7 0.2 0.0047 16.2 0.2 1.2 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF1749 PF08538.5 EGC29196.1 - 0.0046 15.8 0.2 0.0073 15.2 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1749) DUF2305 PF10230.4 EGC29196.1 - 0.0049 16.3 0.1 0.0076 15.7 0.0 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) DUF1057 PF06342.7 EGC29196.1 - 0.0052 15.6 0.0 0.0068 15.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Chlorophyllase2 PF12740.2 EGC29196.1 - 0.0088 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 Chlorophyllase enzyme PAF-AH_p_II PF03403.8 EGC29196.1 - 0.015 13.6 0.0 0.025 12.8 0.0 1.4 1 0 0 1 1 1 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_3 PF07859.8 EGC29196.1 - 0.019 14.5 0.1 1 8.8 0.0 2.3 2 0 0 2 2 2 0 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EGC29196.1 - 0.019 13.7 0.0 0.031 13.0 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase Thioesterase PF00975.15 EGC29196.1 - 0.095 12.9 0.0 0.17 12.0 0.0 1.5 1 1 0 1 1 1 0 Thioesterase domain Esterase PF00756.15 EGC29196.1 - 0.14 11.5 0.0 0.27 10.6 0.0 1.4 1 0 0 1 1 1 0 Putative esterase RinB PF06116.7 EGC29197.1 - 0.065 12.8 0.8 0.25 11.0 0.0 2.3 2 0 0 2 2 2 0 Transcriptional activator RinB MFS_1 PF07690.11 EGC29199.1 - 4.1e-27 94.8 45.1 2.3e-23 82.5 23.7 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGC29199.1 - 2.5e-10 39.3 30.5 9.4e-09 34.1 9.3 2.3 1 1 1 2 2 2 2 MFS/sugar transport protein MFS_3 PF05977.8 EGC29199.1 - 0.58 8.2 15.9 0.59 8.1 4.1 2.1 1 1 1 2 2 2 0 Transmembrane secretion effector NAD_binding_10 PF13460.1 EGC29200.1 - 0.00032 20.7 0.0 0.00077 19.5 0.0 1.7 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGC29200.1 - 0.0014 17.9 0.1 0.0058 15.9 0.0 1.8 2 0 0 2 2 2 1 NmrA-like family NAD_binding_1 PF00175.16 EGC29201.1 - 1.5e-16 60.9 0.1 8.6e-16 58.4 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGC29201.1 - 4e-08 33.3 0.1 1.1e-05 25.4 0.0 2.9 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Globin PF00042.17 EGC29201.1 - 2e-07 31.3 0.0 4.3e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Globin FAD_binding_6 PF00970.19 EGC29201.1 - 7.1e-07 29.2 0.0 2.7e-06 27.4 0.0 2.0 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain Protoglobin PF11563.3 EGC29201.1 - 0.0096 15.5 0.1 0.029 14.0 0.0 1.7 2 0 0 2 2 2 1 Protoglobin Ras PF00071.17 EGC29202.1 - 2.2e-22 79.1 0.5 2.7e-22 78.8 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC29202.1 - 9.1e-07 29.3 0.0 2.2e-06 28.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EGC29202.1 - 0.0078 15.3 1.0 0.014 14.5 0.7 1.6 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGC29202.1 - 0.0099 15.1 0.0 0.02 14.1 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family TFX_C PF14601.1 EGC29202.1 - 0.014 15.1 0.4 0.062 13.0 0.0 2.0 2 0 0 2 2 2 0 DNA_binding protein, TFX, C-term Septin PF00735.13 EGC29202.1 - 0.03 13.3 1.2 0.034 13.1 0.0 1.7 2 0 0 2 2 2 0 Septin zf-U1 PF06220.7 EGC29203.1 - 1.4e-08 34.1 3.7 2.7e-08 33.2 2.6 1.5 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EGC29203.1 - 0.027 14.6 5.4 0.098 12.8 3.7 2.1 1 0 0 1 1 1 0 Zinc-finger double-stranded RNA-binding G-patch PF01585.18 EGC29204.1 - 6.9e-10 38.5 3.0 1.4e-09 37.5 2.1 1.6 1 0 0 1 1 1 1 G-patch domain DUF3439 PF11921.3 EGC29204.1 - 0.5 10.1 23.2 1.7 8.3 5.0 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC29204.1 - 3.5 7.3 38.6 0.48 10.1 6.0 2.7 3 0 0 3 3 3 0 Mucin-like glycoprotein Shisa PF13908.1 EGC29205.1 - 0.0082 16.3 1.2 0.0082 16.3 0.8 1.1 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Serinc PF03348.10 EGC29205.1 - 0.037 12.7 0.5 0.036 12.7 0.4 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) Spore_YhcN_YlaJ PF09580.5 EGC29205.1 - 0.041 14.0 1.4 0.041 13.9 0.9 1.0 1 0 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) FHIPEP PF00771.15 EGC29205.1 - 0.073 11.3 0.2 0.072 11.4 0.1 1.0 1 0 0 1 1 1 0 FHIPEP family ETRAMP PF09716.5 EGC29205.1 - 0.074 13.0 0.0 0.086 12.8 0.0 1.2 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF843 PF05814.6 EGC29205.1 - 0.083 12.6 0.2 0.11 12.3 0.1 1.2 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Mucin PF01456.12 EGC29205.1 - 0.091 12.5 0.1 0.1 12.3 0.1 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein EphA2_TM PF14575.1 EGC29205.1 - 0.098 13.0 0.1 0.11 12.8 0.1 1.2 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain ATP-synt_8 PF00895.15 EGC29205.1 - 0.099 12.8 1.3 0.19 11.9 0.9 1.6 1 1 0 1 1 1 0 ATP synthase protein 8 Corona_nucleoca PF00937.13 EGC29205.1 - 0.11 11.4 4.0 0.12 11.3 2.7 1.0 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein DUF2681 PF10883.3 EGC29205.1 - 0.16 12.1 2.8 0.2 11.9 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2681) IncA PF04156.9 EGC29205.1 - 0.4 10.2 4.2 0.43 10.1 2.9 1.0 1 0 0 1 1 1 0 IncA protein SCIMP PF15050.1 EGC29205.1 - 1.5 8.6 4.2 0.72 9.7 1.2 1.6 1 1 1 2 2 2 0 SCIMP protein DUF3484 PF11983.3 EGC29205.1 - 2.3 9.1 10.0 2.8 8.8 7.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3484) Pex14_N PF04695.8 EGC29205.1 - 8.1 6.5 11.3 9.1 6.3 7.9 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pal1 PF08316.6 EGC29206.1 - 0.039 14.3 6.0 0.046 14.1 4.2 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein LMBR1 PF04791.11 EGC29206.1 - 3.6 6.0 9.1 3.4 6.1 6.3 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DDHD PF02862.12 EGC29206.1 - 4.1 7.1 15.8 5.1 6.8 10.9 1.2 1 0 0 1 1 1 0 DDHD domain CAF-1_p150 PF11600.3 EGC29206.1 - 4.6 6.5 42.3 5.5 6.2 29.4 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal EGF_2 PF07974.8 EGC29207.1 - 7.8e-06 25.9 7.0 1.4e-05 25.1 4.9 1.4 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC29207.1 - 0.00095 19.0 7.0 0.0016 18.3 4.9 1.4 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EGC29207.1 - 0.0069 16.3 5.2 0.013 15.4 3.6 1.4 1 0 0 1 1 1 1 Alliinase EGF-like domain NESP55 PF06390.7 EGC29207.1 - 1.2 8.4 4.5 1.5 8.1 3.1 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) V-SNARE_C PF12352.3 EGC29208.1 - 1.2e-05 25.2 1.4 1.2e-05 25.2 1.0 2.1 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus XhlA PF10779.4 EGC29208.1 - 0.004 17.0 5.0 0.68 9.8 0.0 2.8 3 0 0 3 3 3 2 Haemolysin XhlA DUF1307 PF06998.6 EGC29208.1 - 0.007 16.4 1.8 1.1 9.3 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function (DUF1307) DUF948 PF06103.6 EGC29208.1 - 0.0091 15.8 0.7 0.97 9.3 0.0 2.5 2 1 0 2 2 2 1 Bacterial protein of unknown function (DUF948) Reo_sigmaC PF04582.7 EGC29208.1 - 0.012 14.8 1.2 0.012 14.8 0.9 1.8 2 0 0 2 2 2 0 Reovirus sigma C capsid protein DUF848 PF05852.6 EGC29208.1 - 0.046 13.5 9.3 0.018 14.9 3.2 2.4 1 1 2 3 3 3 0 Gammaherpesvirus protein of unknown function (DUF848) MbeD_MobD PF04899.7 EGC29208.1 - 0.2 11.5 2.4 13 5.7 0.0 2.8 2 0 0 2 2 2 0 MbeD/MobD like Sec20 PF03908.8 EGC29208.1 - 0.47 10.1 7.9 0.49 10.1 0.0 3.4 2 1 2 4 4 4 0 Sec20 TPR_MLP1_2 PF07926.7 EGC29208.1 - 0.92 9.2 14.7 0.15 11.7 3.6 2.8 2 1 1 3 3 2 0 TPR/MLP1/MLP2-like protein NPV_P10 PF05531.7 EGC29208.1 - 0.95 9.7 4.5 5.9 7.2 2.0 2.9 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF2205 PF10224.4 EGC29208.1 - 1.3 8.6 6.2 0.89 9.1 0.8 2.8 3 1 0 3 3 3 0 Predicted coiled-coil protein (DUF2205) CENP-H PF05837.7 EGC29208.1 - 9.7 6.4 10.3 1.4 9.1 1.3 3.0 1 1 2 3 3 3 0 Centromere protein H (CENP-H) OTU PF02338.14 EGC29209.1 - 8e-12 45.8 0.1 9.7e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease ECSIT PF06239.6 EGC29209.1 - 0.083 11.7 0.0 0.16 10.8 0.0 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway tRNA-synt_1 PF00133.17 EGC29212.1 - 9.2e-185 615.0 0.0 4.3e-184 612.8 0.0 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC29212.1 - 1.5e-37 128.7 2.3 3.2e-37 127.6 1.6 1.6 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGC29212.1 - 1.2e-17 63.6 4.6 1.3e-08 33.9 0.0 4.5 4 1 0 4 4 4 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGC29212.1 - 2.7e-08 33.3 0.0 5.4e-05 22.5 0.0 3.0 1 1 1 2 2 2 2 Leucyl-tRNA synthetase, Domain 2 Val_tRNA-synt_C PF10458.4 EGC29212.1 - 0.038 14.0 1.8 0.11 12.5 1.2 1.8 1 0 0 1 1 1 0 Valyl tRNA synthetase tRNA binding arm DUF3664 PF12406.3 EGC29212.1 - 0.34 11.5 5.4 1.1 9.9 3.7 1.8 1 0 0 1 1 1 0 Surface protein Exo_endo_phos PF03372.18 EGC29213.1 - 1.7e-12 47.7 0.0 2.4e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family CoA_binding PF02629.14 EGC29214.1 - 1e-30 106.0 0.7 1e-30 106.0 0.5 2.2 2 0 0 2 2 2 1 CoA binding domain Ligase_CoA PF00549.14 EGC29214.1 - 1e-23 83.6 0.1 3e-23 82.1 0.1 1.8 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EGC29214.1 - 4.3e-08 32.8 0.0 1.5e-07 31.0 0.0 1.9 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding_2 PF13380.1 EGC29214.1 - 0.00093 19.3 0.0 0.0032 17.6 0.0 1.9 2 0 0 2 2 2 1 CoA binding domain Ribul_P_3_epim PF00834.14 EGC29214.1 - 0.034 13.2 0.1 0.058 12.5 0.1 1.3 1 0 0 1 1 1 0 Ribulose-phosphate 3 epimerase family Peptidase_M48 PF01435.13 EGC29215.1 - 2.2e-32 112.4 0.0 3e-32 112.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 SR-25 PF10500.4 EGC29216.1 - 0.15 11.5 12.9 0.24 10.8 9.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF605 PF04652.11 EGC29216.1 - 0.99 8.7 35.8 1.1 8.6 24.8 1.1 1 0 0 1 1 1 0 Vta1 like SprA-related PF12118.3 EGC29216.1 - 3.2 7.0 37.2 4 6.6 25.8 1.1 1 0 0 1 1 1 0 SprA-related family FAM196 PF15265.1 EGC29216.1 - 6 5.9 32.3 7.2 5.7 22.4 1.0 1 0 0 1 1 1 0 FAM196 family TFIIA PF03153.8 EGC29216.1 - 6.5 6.5 39.2 7.3 6.3 27.2 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit RabGAP-TBC PF00566.13 EGC29217.1 - 9.3e-33 113.5 21.8 1.9e-18 66.7 0.9 3.7 3 1 0 3 3 3 2 Rab-GTPase-TBC domain Na_H_Exchanger PF00999.16 EGC29218.1 - 1.3e-55 188.4 50.2 1.8e-55 188.0 34.8 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family DnaJ PF00226.26 EGC29219.1 - 1.3e-23 82.5 0.2 2.4e-23 81.6 0.1 1.5 1 0 0 1 1 1 1 DnaJ domain DUF1836 PF08876.6 EGC29219.1 - 0.0052 16.5 0.1 0.013 15.2 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF1836) DUF1977 PF09320.6 EGC29219.1 - 0.0054 16.9 3.2 0.016 15.4 2.2 1.8 1 1 0 1 1 1 1 Domain of unknown function (DUF1977) Mucin PF01456.12 EGC29219.1 - 0.46 10.2 19.1 0.77 9.5 13.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Med3 PF11593.3 EGC29219.1 - 0.5 9.5 8.2 0.69 9.0 5.7 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Paramyxo_C PF01692.13 EGC29219.1 - 1.4 8.5 5.2 2.9 7.4 3.6 1.5 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c SSP160 PF06933.6 EGC29219.1 - 6.1 4.6 15.0 9 4.1 10.4 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DFP PF04127.10 EGC29221.1 - 2.2e-15 56.7 0.0 4.8e-11 42.6 0.0 2.2 2 0 0 2 2 2 2 DNA / pantothenate metabolism flavoprotein Pkinase_Tyr PF07714.12 EGC29222.1 - 1.3e-51 175.1 0.0 1.8e-51 174.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC29222.1 - 8.1e-48 162.8 0.0 6.8e-47 159.7 0.0 2.2 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGC29222.1 - 0.038 13.7 0.0 0.061 13.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC29222.1 - 0.11 11.5 0.0 0.18 10.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CD99L2 PF12301.3 EGC29223.1 - 0.0053 16.4 4.7 0.0072 16.0 2.6 1.6 2 0 0 2 2 2 1 CD99 antigen like protein 2 Sod_Fe_C PF02777.13 EGC29225.1 - 2.2e-42 143.1 0.2 3.8e-42 142.4 0.2 1.4 1 0 0 1 1 1 1 Iron/manganese superoxide dismutases, C-terminal domain Sod_Fe_N PF00081.17 EGC29225.1 - 2.9e-32 110.7 1.1 2.9e-32 110.7 0.8 1.8 2 0 0 2 2 2 1 Iron/manganese superoxide dismutases, alpha-hairpin domain CesT PF05932.8 EGC29225.1 - 0.0054 16.5 0.0 0.008 16.0 0.0 1.2 1 0 0 1 1 1 1 Tir chaperone protein (CesT) family NUDIX PF00293.23 EGC29226.1 - 1.2e-10 41.1 0.0 1.8e-10 40.5 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DnaA_N PF11638.3 EGC29226.1 - 0.05 13.1 0.1 0.095 12.2 0.0 1.5 1 0 0 1 1 1 0 DnaA N-terminal domain YolD PF08863.5 EGC29226.1 - 0.059 13.2 0.3 0.26 11.1 0.0 2.0 2 0 0 2 2 2 0 YolD-like protein Profilin PF00235.14 EGC29227.1 - 1.9e-37 128.0 1.0 2.1e-37 127.8 0.7 1.0 1 0 0 1 1 1 1 Profilin XPG_I_2 PF12813.2 EGC29229.1 - 1.8e-06 27.6 0.0 3.2e-06 26.8 0.0 1.4 1 0 0 1 1 1 1 XPG domain containing XPG_I PF00867.13 EGC29229.1 - 1.5e-05 24.9 0.0 3.1e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGC29229.1 - 5.8e-05 23.2 0.1 0.00016 21.8 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain UFD1 PF03152.9 EGC29230.1 - 4.4e-79 263.6 0.0 5.4e-79 263.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin fusion degradation protein UFD1 CDC48_2 PF02933.12 EGC29230.1 - 0.049 13.2 0.0 0.12 11.9 0.0 1.7 1 1 1 2 2 2 0 Cell division protein 48 (CDC48), domain 2 Yip1 PF04893.12 EGC29231.1 - 1.5e-07 31.0 14.2 4.6e-06 26.2 6.9 2.1 1 1 1 2 2 2 2 Yip1 domain UPF0051 PF01458.12 EGC29232.1 - 0.034 13.5 1.8 0.044 13.2 0.2 1.9 2 0 0 2 2 2 0 Uncharacterized protein family (UPF0051) DUF948 PF06103.6 EGC29232.1 - 0.64 9.9 4.5 52 3.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) 7kD_coat PF02495.12 EGC29232.1 - 3.3 7.2 8.8 0.32 10.4 0.1 2.9 3 0 0 3 3 3 0 7kD viral coat protein TPR_11 PF13414.1 EGC29233.1 - 4.5e-34 115.9 20.3 5.8e-07 29.0 0.3 8.4 4 2 5 10 10 10 10 TPR repeat TPR_2 PF07719.12 EGC29233.1 - 5e-27 91.6 6.9 0.00066 19.3 0.0 11.8 11 0 0 11 11 11 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC29233.1 - 3.1e-24 85.0 0.0 0.00091 19.8 0.0 7.3 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGC29233.1 - 1.7e-23 81.2 17.4 2.8e-05 23.5 0.0 11.8 13 0 0 13 13 12 5 Tetratricopeptide repeat TPR_19 PF14559.1 EGC29233.1 - 1e-19 70.6 20.9 2.4e-06 27.8 0.0 8.3 8 1 1 9 9 8 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGC29233.1 - 4.5e-19 67.2 0.0 0.0065 17.0 0.1 9.3 6 2 4 10 10 9 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29233.1 - 1.3e-18 65.2 25.1 0.00039 19.9 0.0 11.9 14 0 0 14 14 11 5 Tetratricopeptide repeat Apc3 PF12895.2 EGC29233.1 - 2.8e-13 49.8 26.5 0.00024 21.1 0.2 7.6 6 2 2 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGC29233.1 - 7.8e-12 44.4 26.3 1.5 9.2 0.1 12.1 13 0 0 13 13 12 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGC29233.1 - 2.5e-11 43.3 27.8 0.00015 21.6 0.7 8.4 6 2 3 9 9 9 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGC29233.1 - 6.1e-10 38.1 1.0 1.3 8.9 0.1 7.9 8 0 0 8 8 7 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC29233.1 - 2.3e-08 33.7 0.0 0.015 15.1 0.0 5.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC29233.1 - 1.7e-07 31.2 13.0 0.59 10.7 0.0 8.6 9 0 0 9 9 9 2 Tetratricopeptide repeat ChAPs PF09295.5 EGC29233.1 - 0.0045 15.7 10.1 0.014 14.1 0.3 3.7 3 1 1 4 4 4 2 ChAPs (Chs5p-Arf1p-binding proteins) PPTA PF01239.17 EGC29233.1 - 0.078 12.3 3.0 0.2 11.0 0.2 3.1 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat APC_CDC26 PF10471.4 EGC29233.1 - 0.13 13.0 11.0 0.44 11.3 7.6 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF3963 PF13124.1 EGC29233.1 - 0.74 9.6 2.0 1 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3963) 3-HAO PF06052.7 EGC29234.1 - 1.4e-60 203.1 0.2 1.6e-60 202.8 0.1 1.1 1 0 0 1 1 1 1 3-hydroxyanthranilic acid dioxygenase Cupin_2 PF07883.6 EGC29234.1 - 1.5e-06 27.6 0.0 1.9e-06 27.2 0.0 1.2 1 0 0 1 1 1 1 Cupin domain Cupin_1 PF00190.17 EGC29234.1 - 0.064 12.7 0.0 0.086 12.2 0.0 1.3 1 0 0 1 1 1 0 Cupin DDE_Tnp_4 PF13359.1 EGC29235.1 - 1.1e-12 47.8 0.0 1.6e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Pterin_4a PF01329.14 EGC29236.1 - 2e-30 104.4 0.1 2.3e-30 104.1 0.1 1.0 1 0 0 1 1 1 1 Pterin 4 alpha carbinolamine dehydratase Oxysterol_BP PF01237.13 EGC29236.1 - 0.1 11.0 0.0 0.11 10.9 0.0 1.1 1 0 0 1 1 1 0 Oxysterol-binding protein P34-Arc PF04045.9 EGC29237.1 - 1.1e-35 123.1 0.0 1.4e-35 122.7 0.0 1.1 1 0 0 1 1 1 1 Arp2/3 complex, 34 kD subunit p34-Arc DEAD PF00270.24 EGC29238.1 - 8.4e-47 158.7 0.1 2.1e-46 157.4 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC29238.1 - 1.9e-22 78.9 0.0 4.1e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGC29238.1 - 1.2e-20 72.7 0.2 2.7e-20 71.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Zw10 PF06248.8 EGC29240.1 - 2.3e-37 128.4 47.8 1.6e-36 125.6 32.0 2.4 1 1 0 1 1 1 1 Centromere/kinetochore Zw10 Zip PF02535.17 EGC29241.1 - 0.047 12.6 2.4 0.16 10.9 0.0 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Vps26 PF03643.10 EGC29242.1 - 1.6e-121 404.3 5.8 3.3e-121 403.3 4.0 1.5 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 tRNA-synt_2 PF00152.15 EGC29242.1 - 1.4e-94 316.6 0.0 2.6e-94 315.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) FNIP PF05725.7 EGC29242.1 - 6.1e-91 298.1 50.8 1.7e-14 53.4 0.1 8.8 4 1 4 9 9 9 9 FNIP Repeat GAD PF02938.9 EGC29242.1 - 6e-11 42.3 0.9 4.4e-10 39.5 0.0 2.3 2 0 0 2 2 2 1 GAD domain tRNA_anti-codon PF01336.20 EGC29242.1 - 2.5e-09 36.8 0.5 6.4e-09 35.5 0.3 1.8 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGC29242.1 - 0.016 14.4 0.1 0.042 13.0 0.0 1.7 1 1 0 1 1 1 0 tRNA synthetases class II core domain (F) EpsG PF14897.1 EGC29243.1 - 0.0015 17.4 13.1 0.055 12.3 3.3 2.1 2 0 0 2 2 2 2 EpsG family Cadherin-like PF12733.2 EGC29243.1 - 0.002 18.3 1.2 7.7 6.8 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like beta sandwich domain DUF2057 PF09829.4 EGC29243.1 - 0.0022 17.6 0.0 3.2 7.3 0.0 2.8 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2057) Med20 PF08612.6 EGC29243.1 - 0.011 14.9 0.3 0.6 9.2 0.0 2.4 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RSD-2 PF07547.8 EGC29243.1 - 0.033 14.3 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 RSD-2 N-terminal domain DUF3598 PF12204.3 EGC29243.1 - 0.3 10.3 1.9 9.3 5.3 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) DUF2970 PF11174.3 EGC29243.1 - 2.3 7.8 5.2 3.8 7.1 0.4 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DUF4064 PF13273.1 EGC29246.1 - 0.056 13.5 0.0 0.056 13.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) zf-RING_2 PF13639.1 EGC29247.1 - 6.4e-10 38.7 8.1 1.5e-09 37.5 5.6 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29247.1 - 2.7e-08 33.3 5.6 5.3e-08 32.3 3.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29247.1 - 7.3e-07 28.7 9.9 2.1e-06 27.3 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29247.1 - 1.1e-06 28.5 9.1 2.7e-06 27.2 6.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29247.1 - 2.8e-05 23.7 7.3 7.3e-05 22.4 5.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29247.1 - 0.00026 20.8 9.3 0.00065 19.5 6.4 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC29247.1 - 0.00073 19.6 5.0 0.0019 18.2 3.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger LMBR1 PF04791.11 EGC29247.1 - 0.0014 17.3 0.0 0.0014 17.3 0.0 2.4 1 1 1 2 2 1 1 LMBR1-like membrane protein zf-RING_4 PF14570.1 EGC29247.1 - 0.0016 17.9 8.1 0.0038 16.7 5.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_6 PF14835.1 EGC29247.1 - 0.0069 16.1 1.5 0.015 15.0 1.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC29247.1 - 0.0076 15.9 6.0 0.035 13.8 4.2 2.2 1 0 0 1 1 1 1 RING-type zinc-finger zf-MIZ PF02891.15 EGC29247.1 - 0.089 12.3 7.4 0.2 11.1 5.1 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DZR PF12773.2 EGC29247.1 - 0.33 10.8 4.6 0.93 9.3 3.1 1.8 1 1 0 1 1 1 0 Double zinc ribbon Fanconi_A PF03511.9 EGC29248.1 - 0.15 11.8 0.8 0.27 11.0 0.5 1.4 1 0 0 1 1 1 0 Fanconi anaemia group A protein WD40 PF00400.27 EGC29250.1 - 1.8e-40 135.3 22.3 4.2e-10 39.1 0.2 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGC29250.1 - 0.0013 17.5 13.9 0.21 10.2 6.2 2.2 1 1 1 2 2 2 2 Nup133 N terminal like PQQ_2 PF13360.1 EGC29250.1 - 0.0066 15.9 1.0 0.34 10.3 0.0 2.9 1 1 1 3 3 3 1 PQQ-like domain TPP1 PF10341.4 EGC29250.1 - 0.075 13.0 0.9 0.22 11.5 0.2 2.1 1 1 1 2 2 2 0 Shelterin complex subunit, TPP1/ACD Etmic-2 PF06670.6 EGC29250.1 - 0.084 11.5 0.1 0.12 11.0 0.1 1.2 1 0 0 1 1 1 0 Microneme protein Etmic-2 Prefoldin PF02996.12 EGC29251.1 - 1.7e-20 72.8 1.6 1.7e-20 72.8 1.1 3.1 3 1 0 3 3 3 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGC29251.1 - 2.9e-08 33.3 0.3 2.9e-08 33.3 0.2 4.0 3 1 1 4 4 4 1 Prefoldin subunit Abhydrolase_5 PF12695.2 EGC29252.1 - 5.6e-06 26.1 0.0 1.2e-05 25.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC29252.1 - 0.0014 17.8 0.0 0.0041 16.3 0.0 1.8 1 1 0 1 1 1 1 Prolyl oligopeptidase family NatB_MDM20 PF09797.4 EGC29253.1 - 0.0051 15.5 0.0 0.0075 15.0 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit Ycf15 PF10705.4 EGC29253.1 - 0.024 14.7 0.0 0.065 13.2 0.0 1.7 1 1 1 2 2 2 0 Chloroplast protein precursor Ycf15 putative Leuk-A4-hydro_C PF09127.6 EGC29253.1 - 0.043 13.4 0.2 0.081 12.5 0.1 1.5 1 0 0 1 1 1 0 Leukotriene A4 hydrolase, C-terminal Pkinase PF00069.20 EGC29254.1 - 8.5e-63 211.9 0.0 1.2e-62 211.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29254.1 - 2.2e-62 210.5 0.0 2.8e-62 210.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC29254.1 - 0.0012 18.5 0.0 0.0041 16.8 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mid2 PF04478.7 EGC29254.1 - 0.0031 16.9 0.3 0.0065 15.8 0.2 1.4 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor TMEM154 PF15102.1 EGC29254.1 - 0.022 14.4 1.7 0.026 14.2 0.2 1.8 2 0 0 2 2 2 0 TMEM154 protein family MLANA PF14991.1 EGC29254.1 - 0.035 14.1 0.0 0.098 12.6 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A DUF1180 PF06679.7 EGC29254.1 - 0.18 11.6 1.2 0.33 10.8 0.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) MGC-24 PF05283.6 EGC29254.1 - 0.57 9.9 7.4 1.1 8.9 5.1 1.5 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) E1-E2_ATPase PF00122.15 EGC29255.1 - 7.7e-62 208.3 1.1 1.9e-61 207.0 0.8 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC29255.1 - 1.6e-42 145.0 4.1 1.6e-42 145.0 2.8 2.9 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC29255.1 - 2.3e-26 93.5 0.0 1.8e-25 90.6 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC29255.1 - 6.7e-17 61.2 0.1 1.5e-16 60.1 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGC29255.1 - 4.4e-15 56.3 0.0 1.2e-14 54.9 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC29255.1 - 2e-12 46.3 0.1 6.7e-12 44.6 0.0 2.0 1 1 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGC29255.1 - 1.6e-05 24.6 1.6 0.0016 18.0 0.0 2.8 3 0 0 3 3 3 2 haloacid dehalogenase-like hydrolase SdpI PF13630.1 EGC29255.1 - 4.4 7.0 23.5 0.086 12.5 2.7 3.6 3 0 0 3 3 3 0 SdpI/YhfL protein family DUF1469 PF07332.6 EGC29255.1 - 7.3 6.3 11.0 0.18 11.5 0.9 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) Complex1_LYR PF05347.10 EGC29256.1 - 1.1e-09 37.9 1.9 1.6e-09 37.4 1.3 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC29256.1 - 3.4e-07 30.3 1.2 5e-07 29.8 0.8 1.3 1 0 0 1 1 1 1 Complex1_LYR-like BRCT_assoc PF12820.2 EGC29257.1 - 0.046 13.4 0.1 0.048 13.4 0.0 1.1 1 0 0 1 1 1 0 Serine-rich domain associated with BRCT IBR PF01485.16 EGC29258.1 - 8.2e-24 83.2 45.6 4.5e-14 52.0 2.7 4.6 3 1 1 4 4 4 3 IBR domain zf-RING_2 PF13639.1 EGC29258.1 - 4.7e-06 26.3 7.1 4.7e-06 26.3 4.9 3.7 2 1 1 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGC29258.1 - 1.4e-05 24.5 4.9 1.4e-05 24.5 3.4 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29258.1 - 0.0011 18.6 7.5 0.0011 18.6 5.2 3.9 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC29258.1 - 0.0016 18.4 7.4 0.0016 18.4 5.2 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF3048 PF11258.3 EGC29259.1 - 0.015 14.4 1.4 0.017 14.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3048) LCAT PF02450.10 EGC29259.1 - 0.065 12.1 1.8 0.063 12.2 1.2 1.1 1 0 0 1 1 1 0 Lecithin:cholesterol acyltransferase IBR PF01485.16 EGC29260.1 - 6.9e-19 67.4 32.9 5.9e-12 45.2 5.4 3.9 3 1 0 3 3 3 2 IBR domain zf-RING_5 PF14634.1 EGC29260.1 - 1.8e-06 27.5 10.5 1.8e-06 27.5 7.3 3.5 3 1 0 3 3 3 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC29260.1 - 0.00027 20.6 8.7 0.00027 20.6 6.0 4.3 3 1 0 3 3 3 2 Ring finger domain zf-C3HC4 PF00097.20 EGC29260.1 - 0.021 14.5 12.0 0.021 14.5 8.3 5.6 3 2 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29260.1 - 0.022 14.7 11.6 0.022 14.7 8.0 5.1 5 0 0 5 5 5 0 Zinc finger, C3HC4 type (RING finger) Linker_histone PF00538.14 EGC29261.1 - 0.52 10.4 3.7 1.6 8.8 0.7 2.9 2 0 0 2 2 2 0 linker histone H1 and H5 family Ctr PF04145.10 EGC29262.1 - 1.1 9.2 5.3 1.3 9.1 0.0 2.4 2 1 0 2 2 2 0 Ctr copper transporter family Spt4 PF06093.8 EGC29265.1 - 2.3e-24 85.0 0.2 2.7e-24 84.8 0.1 1.1 1 0 0 1 1 1 1 Spt4/RpoE2 zinc finger Integrin_B_tail PF07965.7 EGC29265.1 - 0.033 14.6 3.1 0.045 14.1 2.2 1.1 1 0 0 1 1 1 0 Integrin beta tail domain DZR PF12773.2 EGC29265.1 - 0.21 11.4 3.0 0.33 10.8 2.1 1.2 1 0 0 1 1 1 0 Double zinc ribbon FNIP PF05725.7 EGC29266.1 - 7.3e-58 192.2 45.1 2.4e-08 33.8 0.6 9.1 5 2 5 10 10 10 10 FNIP Repeat LRR_5 PF13306.1 EGC29266.1 - 0.066 12.9 4.5 0.32 10.7 0.2 3.5 3 1 0 3 3 3 0 Leucine rich repeats (6 copies) VPS28 PF03997.7 EGC29267.1 - 6.7e-64 214.9 1.5 8.1e-64 214.7 1.0 1.1 1 0 0 1 1 1 1 VPS28 protein UvrD_C PF13361.1 EGC29267.1 - 0.0042 16.5 3.7 0.019 14.4 2.6 1.8 1 1 0 1 1 1 1 UvrD-like helicase C-terminal domain RFC1 PF08519.7 EGC29267.1 - 0.0096 15.6 1.5 0.69 9.6 0.0 3.4 1 1 2 3 3 3 1 Replication factor RFC1 C terminal domain PilM_2 PF11104.3 EGC29267.1 - 0.074 11.9 0.0 0.13 11.0 0.0 1.3 1 0 0 1 1 1 0 Type IV pilus assembly protein PilM; Aa_trans PF01490.13 EGC29268.1 - 9.5e-10 37.5 38.9 1.5e-09 36.8 26.9 1.3 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein Trp_Tyr_perm PF03222.8 EGC29268.1 - 0.57 8.9 32.0 5.2 5.7 18.4 3.1 1 1 1 2 2 2 0 Tryptophan/tyrosine permease family DUF373 PF04123.8 EGC29268.1 - 7.4 5.4 20.6 0.019 14.0 5.7 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF373) DEAD PF00270.24 EGC29269.1 - 1.4e-19 70.2 0.0 6.4e-19 68.0 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC29269.1 - 5.6e-19 67.7 0.3 3.1e-18 65.3 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain RQC PF09382.5 EGC29269.1 - 1.5e-13 50.3 0.0 5.3e-13 48.6 0.0 2.0 1 0 0 1 1 1 1 RQC domain HRDC PF00570.18 EGC29269.1 - 2.9e-11 42.8 0.0 7.2e-11 41.6 0.0 1.6 1 0 0 1 1 1 1 HRDC domain Abhydrolase_2 PF02230.11 EGC29270.1 - 1.5e-41 142.2 0.0 1.7e-41 142.0 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGC29270.1 - 5.8e-10 39.0 0.0 7.7e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGC29270.1 - 0.00017 21.1 0.0 0.00046 19.7 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGC29270.1 - 0.00021 21.2 0.0 0.047 13.5 0.0 2.3 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC29270.1 - 0.0013 17.9 0.1 0.019 14.1 0.0 2.4 2 1 0 3 3 3 1 Prolyl oligopeptidase family DLH PF01738.13 EGC29270.1 - 0.0041 16.4 0.0 0.0058 15.9 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family DUF690 PF05108.8 EGC29270.1 - 0.028 12.8 0.0 0.033 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF690) Abhydrolase_1 PF00561.15 EGC29270.1 - 0.11 12.0 0.2 0.45 10.0 0.1 2.1 2 1 0 2 2 2 0 alpha/beta hydrolase fold Ank_2 PF12796.2 EGC29271.1 - 0.00056 20.2 0.1 0.26 11.6 0.0 2.7 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC29271.1 - 0.03 14.8 0.8 5.6 7.6 0.0 3.8 4 0 0 4 4 4 0 Ankyrin repeats (many copies) PRA1 PF03208.14 EGC29272.1 - 0.12 11.6 0.0 0.16 11.2 0.0 1.2 1 0 0 1 1 1 0 PRA1 family protein SR-25 PF10500.4 EGC29274.1 - 0.023 14.1 7.3 0.038 13.4 5.0 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RabGAP-TBC PF00566.13 EGC29275.1 - 1.7e-60 204.1 2.2 4.7e-60 202.7 1.5 1.8 1 0 0 1 1 1 1 Rab-GTPase-TBC domain Ank PF00023.25 EGC29275.1 - 5.4e-11 41.7 0.2 4e-09 35.8 0.2 2.8 2 0 0 2 2 2 1 Ankyrin repeat Ank_2 PF12796.2 EGC29275.1 - 6.5e-10 39.2 0.0 2.5e-09 37.3 0.0 1.9 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC29275.1 - 4e-08 33.2 0.0 1.4e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC29275.1 - 9.7e-07 28.4 0.1 0.00015 21.7 0.1 2.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGC29275.1 - 5.9e-05 23.4 0.0 0.00078 19.8 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) DUF998 PF06197.8 EGC29276.1 - 0.081 12.2 2.3 0.093 12.0 1.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF998) DUF4131 PF13567.1 EGC29276.1 - 0.55 9.6 2.3 0.6 9.5 1.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Dynamin_N PF00350.18 EGC29277.1 - 2.6e-23 82.6 1.1 2.3e-12 47.0 0.0 4.1 4 2 1 5 5 5 2 Dynamin family MMR_HSR1 PF01926.18 EGC29277.1 - 6.1e-14 51.9 0.1 6.1e-14 51.9 0.1 3.0 3 1 0 3 3 3 1 50S ribosome-binding GTPase Miro PF08477.8 EGC29277.1 - 2.3e-07 31.3 4.3 8.6e-07 29.4 0.1 3.4 4 0 0 4 4 3 1 Miro-like protein GTP_EFTU PF00009.22 EGC29277.1 - 7.7e-07 28.7 0.7 7.7e-07 28.7 0.5 2.1 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGC29277.1 - 0.00077 18.7 0.3 0.63 9.3 0.0 2.6 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF4325 PF14213.1 EGC29277.1 - 0.0021 17.6 0.6 1.1 8.9 0.0 4.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4325) FtsK_SpoIIIE PF01580.13 EGC29277.1 - 0.0021 17.5 0.5 0.35 10.3 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family ATP_bind_1 PF03029.12 EGC29277.1 - 0.0031 17.0 1.6 0.39 10.2 0.1 3.3 2 1 1 3 3 3 1 Conserved hypothetical ATP binding protein DUF258 PF03193.11 EGC29277.1 - 0.0097 15.1 0.0 0.033 13.3 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Osmo_CC PF08946.5 EGC29277.1 - 0.094 12.7 4.0 3.6 7.6 0.1 3.0 2 0 0 2 2 2 0 Osmosensory transporter coiled coil DUF948 PF06103.6 EGC29277.1 - 5.9 6.8 9.8 3 7.7 0.0 3.9 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) zf-4CXXC_R1 PF10497.4 EGC29279.1 - 4.9e-07 29.8 12.2 1.3e-06 28.5 8.5 1.7 1 0 0 1 1 1 1 Zinc-finger domain of monoamine-oxidase A repressor R1 WD40 PF00400.27 EGC29280.1 - 5.3e-23 79.9 8.9 2.1e-08 33.7 0.2 5.4 6 0 0 6 6 6 3 WD domain, G-beta repeat zf-C3HC4_3 PF13920.1 EGC29280.1 - 4.3e-08 32.6 4.0 8.3e-08 31.7 2.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29280.1 - 6.8e-08 32.4 9.5 1.7e-07 31.1 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29280.1 - 2.8e-07 30.0 8.6 2.8e-07 30.0 5.9 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC29280.1 - 1e-05 25.1 2.6 2.6e-05 23.8 1.8 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_5 PF14634.1 EGC29280.1 - 1.1e-05 25.0 8.5 2.8e-05 23.7 5.9 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC29280.1 - 1.2e-05 25.0 9.3 2.2e-05 24.1 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGC29280.1 - 1.2e-05 25.0 11.4 3e-05 23.7 7.9 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING F-box PF00646.28 EGC29280.1 - 0.001 18.6 0.0 0.0022 17.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGC29280.1 - 0.0061 16.2 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 F-box-like zf-RING_6 PF14835.1 EGC29280.1 - 0.059 13.1 1.9 0.14 11.9 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGC29280.1 - 0.64 10.1 6.2 1.5 8.9 4.3 1.7 1 0 0 1 1 1 0 RING-H2 zinc finger Patatin PF01734.17 EGC29282.1 - 2.1e-17 63.7 0.0 5.6e-16 59.0 0.0 2.6 2 1 0 2 2 2 1 Patatin-like phospholipase NTS PF15447.1 EGC29282.1 - 0.076 13.4 0.1 0.22 11.9 0.0 1.7 1 0 0 1 1 1 0 N-terminal segments of PfEMP1 Microcin PF03526.8 EGC29283.1 - 0.28 10.8 5.7 2.6 7.7 1.0 2.7 1 1 2 3 3 3 0 Colicin E1 (microcin) immunity protein EGF_2 PF07974.8 EGC29284.1 - 0.28 11.3 9.1 0.67 10.1 6.3 1.7 1 0 0 1 1 1 0 EGF-like domain FF PF01846.14 EGC29285.1 - 6.9e-36 121.9 37.1 1.2e-10 41.2 0.1 6.6 7 1 1 8 8 8 5 FF domain WW PF00397.21 EGC29285.1 - 1.1e-14 53.9 12.0 8.9e-07 28.6 3.4 3.4 3 0 0 3 3 3 2 WW domain PRP38_assoc PF12871.2 EGC29285.1 - 7.7e-05 23.1 17.5 7.7e-05 23.1 12.1 2.7 4 0 0 4 4 4 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term FNIP PF05725.7 EGC29286.1 - 2.1e-36 123.6 53.0 1.1e-06 28.4 0.8 11.0 5 2 2 9 9 9 9 FNIP Repeat zf-B_box PF00643.19 EGC29286.1 - 1.2e-07 31.5 10.8 2.7e-07 30.3 7.5 1.6 1 0 0 1 1 1 1 B-box zinc finger BHD_1 PF10403.4 EGC29286.1 - 0.0081 15.6 0.3 0.05 13.1 0.0 2.5 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 CENP-B_dimeris PF09026.5 EGC29286.1 - 0.039 14.1 1.6 0.087 13.0 1.1 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain CAP PF00188.21 EGC29288.1 - 2.1e-13 50.8 5.9 2.1e-13 50.8 4.1 2.1 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Yip1 PF04893.12 EGC29289.1 - 5.8e-09 35.6 11.2 7.7e-09 35.2 7.7 1.2 1 0 0 1 1 1 1 Yip1 domain Dicty_spore_N PF04562.7 EGC29290.1 - 4.3e-63 210.8 61.1 2e-34 118.4 18.7 3.3 3 0 0 3 3 3 2 Dictyostelium spore coat protein, N terminus Cauli_VI PF01693.11 EGC29290.1 - 0.03 14.3 0.5 0.34 10.9 0.1 2.3 2 0 0 2 2 2 0 Caulimovirus viroplasmin DUF605 PF04652.11 EGC29290.1 - 2.2 7.6 49.2 0.41 9.9 27.1 2.3 2 0 0 2 2 2 0 Vta1 like G-alpha PF00503.15 EGC29291.1 - 0.019 13.6 2.3 0.026 13.2 1.5 1.3 1 1 0 1 1 1 0 G-protein alpha subunit Imm8 PF15560.1 EGC29291.1 - 0.1 12.2 1.1 3.3 7.3 0.0 2.0 1 1 1 2 2 2 0 Immunity protein 8 DUF3879 PF12995.2 EGC29291.1 - 0.23 11.0 1.5 1.4 8.4 1.0 1.9 1 1 0 1 1 1 0 Domain of unknown function, E. rectale Gene description (DUF3879) GTP_EFTU PF00009.22 EGC29292.1 - 1e-49 168.5 0.0 1.7e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain LepA_C PF06421.7 EGC29292.1 - 6.5e-45 151.4 1.3 1.4e-44 150.3 0.9 1.6 1 0 0 1 1 1 1 GTP-binding protein LepA C-terminus EFG_C PF00679.19 EGC29292.1 - 3.9e-16 58.6 0.0 8.1e-16 57.6 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC29292.1 - 2.5e-05 24.3 0.6 5.9e-05 23.1 0.4 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC29292.1 - 6.5e-05 22.8 0.1 0.00015 21.7 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC29292.1 - 0.00069 19.1 0.4 0.0052 16.2 0.0 2.3 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC29292.1 - 0.001 18.2 0.2 0.0038 16.4 0.1 1.9 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC29292.1 - 0.0046 16.3 0.1 0.015 14.6 0.0 1.8 2 0 0 2 2 2 1 Ras family EFG_II PF14492.1 EGC29292.1 - 0.032 14.0 0.1 0.21 11.4 0.1 2.1 1 1 0 1 1 1 0 Elongation Factor G, domain II CbiA PF01656.18 EGC29292.1 - 0.23 10.8 2.8 0.31 10.4 0.0 2.0 1 1 1 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain DUF1968 PF09291.5 EGC29293.1 - 0.11 12.3 0.2 0.21 11.4 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF1968) DUF2704 PF10866.3 EGC29293.1 - 0.23 10.8 9.6 0.044 13.1 3.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF2704) HOOK PF05622.7 EGC29293.1 - 0.23 9.2 21.6 0.25 9.1 15.0 1.1 1 0 0 1 1 1 0 HOOK protein hDGE_amylase PF14701.1 EGC29293.1 - 6.7 5.4 10.2 7.8 5.2 7.1 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme IncA PF04156.9 EGC29293.1 - 9.4 5.7 26.0 13 5.2 17.7 1.6 1 1 1 2 2 2 0 IncA protein zf-C3HC4_3 PF13920.1 EGC29294.1 - 4.2e-06 26.3 6.6 4.2e-06 26.3 4.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29294.1 - 1.5e-05 24.5 8.5 1.5e-05 24.5 5.9 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29294.1 - 1.9e-05 24.4 4.6 1.9e-05 24.4 3.2 2.6 2 2 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGC29294.1 - 0.00019 21.3 5.3 0.00019 21.3 3.7 2.8 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGC29294.1 - 0.017 14.8 5.1 0.017 14.8 3.6 1.7 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_2 PF13639.1 EGC29294.1 - 1.9 8.4 17.5 0.1 12.4 3.8 2.8 1 1 1 2 2 2 0 Ring finger domain Prok-RING_4 PF14447.1 EGC29294.1 - 3.5 7.2 11.5 0.18 11.3 1.5 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 Gelsolin PF00626.17 EGC29295.1 - 8.8e-17 60.5 17.0 2.5e-05 23.8 0.0 7.6 8 0 0 8 8 8 4 Gelsolin repeat Caldesmon PF02029.10 EGC29295.1 - 0.00058 18.4 42.3 0.0017 16.8 11.2 2.3 2 0 0 2 2 2 2 Caldesmon Cnd1 PF12717.2 EGC29296.1 - 4.2 7.1 13.3 6 6.6 5.3 2.9 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Oxysterol_BP PF01237.13 EGC29297.1 - 4.2e-59 199.8 2.4 5.9e-59 199.3 1.7 1.1 1 0 0 1 1 1 1 Oxysterol-binding protein HECT_2 PF09814.4 EGC29298.1 - 1e-08 34.3 1.8 1.3e-08 33.9 1.3 1.1 1 0 0 1 1 1 1 HECT-like Ubiquitin-conjugating enzyme (E2)-binding GCIP PF13324.1 EGC29299.1 - 2.1e-16 60.0 16.3 9.6e-15 54.5 11.3 2.2 1 1 0 1 1 1 1 Grap2 and cyclin-D-interacting DUF2806 PF10987.3 EGC29299.1 - 0.015 14.7 0.2 0.079 12.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2806) RNA_pol_3_Rpc31 PF11705.3 EGC29299.1 - 2.1 8.1 18.1 5.1 6.9 12.5 1.7 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 EGF_2 PF07974.8 EGC29300.1 - 0.0039 17.3 9.6 0.0079 16.3 6.6 1.5 1 0 0 1 1 1 1 EGF-like domain DUF2613 PF11021.3 EGC29300.1 - 0.088 12.5 0.8 0.21 11.2 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) Peptidase_M20 PF01546.23 EGC29301.1 - 1.1e-19 70.7 0.0 1.6e-19 70.2 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC29301.1 - 2e-13 50.0 0.0 3.1e-13 49.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase dimerisation domain DUF2185 PF09951.4 EGC29302.1 - 2.5e-19 68.8 0.9 5.5e-19 67.7 0.1 2.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2185) DUF2314 PF10077.4 EGC29302.1 - 0.00016 21.7 0.0 0.00031 20.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2314) Frataxin_Cyay PF01491.11 EGC29302.1 - 0.074 12.8 0.5 1.3 8.8 0.1 2.1 2 0 0 2 2 2 0 Frataxin-like domain ERCC4 PF02732.10 EGC29303.1 - 6.2e-20 71.4 2.7 8.8e-20 70.9 0.1 2.5 2 0 0 2 2 2 1 ERCC4 domain SAM_1 PF00536.25 EGC29303.1 - 0.0022 18.0 0.0 0.0063 16.6 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC29303.1 - 0.011 15.5 0.6 0.061 13.1 0.0 2.5 3 0 0 3 3 3 0 SAM domain (Sterile alpha motif) SNARE PF05739.14 EGC29304.1 - 4e-06 26.4 3.2 9.9e-06 25.1 2.2 1.7 1 0 0 1 1 1 1 SNARE domain FliJ PF02050.11 EGC29304.1 - 0.0042 17.1 4.8 0.022 14.7 0.5 2.3 2 0 0 2 2 2 1 Flagellar FliJ protein TPR_MLP1_2 PF07926.7 EGC29304.1 - 0.018 14.7 10.0 0.66 9.7 1.9 2.3 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein DegS PF05384.6 EGC29304.1 - 0.03 13.5 2.5 0.14 11.3 0.1 2.6 2 1 0 2 2 2 0 Sensor protein DegS DUF948 PF06103.6 EGC29304.1 - 0.033 14.0 1.4 0.033 14.0 1.0 2.6 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Synaptobrevin PF00957.16 EGC29304.1 - 0.05 13.2 0.2 0.17 11.5 0.1 1.9 1 0 0 1 1 1 0 Synaptobrevin FH2 PF02181.18 EGC29304.1 - 0.24 10.2 5.8 1.5 7.5 0.3 2.2 2 0 0 2 2 2 0 Formin Homology 2 Domain Uds1 PF15456.1 EGC29304.1 - 0.32 10.9 3.5 1.2 9.1 0.1 2.4 2 0 0 2 2 2 0 Up-regulated During Septation BLOC1_2 PF10046.4 EGC29304.1 - 2.2 8.4 6.6 0.78 9.9 0.7 2.6 3 0 0 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF4463 PF14703.1 EGC29304.1 - 8.5 6.9 9.5 2.5 8.6 0.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) adh_short PF00106.20 EGC29306.1 - 1.9e-21 76.6 0.0 2.4e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29306.1 - 1.5e-08 34.5 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGC29306.1 - 0.00021 20.9 0.4 0.00063 19.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase DUF3439 PF11921.3 EGC29307.1 - 0.69 9.6 5.1 1.7 8.4 3.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) OTU PF02338.14 EGC29309.1 - 2.5e-12 47.4 0.0 2.5e-12 47.4 0.0 2.7 2 1 0 2 2 1 1 OTU-like cysteine protease Exonuc_VII_L PF02601.10 EGC29309.1 - 0.048 12.8 11.1 0.056 12.6 7.7 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF3810 PF12725.2 EGC29309.1 - 0.075 11.9 7.0 0.12 11.2 4.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) Nucleoside_tran PF01733.13 EGC29309.1 - 0.087 11.9 3.2 0.14 11.2 2.2 1.4 1 0 0 1 1 1 0 Nucleoside transporter DUF572 PF04502.8 EGC29309.1 - 0.12 11.5 14.5 0.16 11.1 10.0 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) HIM1 PF08732.5 EGC29309.1 - 0.18 10.2 5.8 0.24 9.8 4.0 1.2 1 0 0 1 1 1 0 HIM1 Nop53 PF07767.6 EGC29309.1 - 0.23 10.4 17.4 0.31 9.9 12.1 1.1 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) Med15 PF09606.5 EGC29309.1 - 0.59 8.2 39.6 0.73 7.9 27.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Cellulose_synt PF03552.9 EGC29309.1 - 0.82 7.8 3.8 1.1 7.5 2.6 1.1 1 0 0 1 1 1 0 Cellulose synthase DUF4407 PF14362.1 EGC29309.1 - 2 7.2 12.7 3.3 6.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3573 PF12097.3 EGC29309.1 - 2.5 6.6 8.5 3.7 6.0 5.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TraV PF09676.5 EGC29309.1 - 3 8.5 7.5 6.9 7.4 5.2 1.6 1 0 0 1 1 1 0 Type IV conjugative transfer system lipoprotein (TraV) Shisa PF13908.1 EGC29309.1 - 5.1 7.2 15.7 21 5.2 10.9 2.0 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4355 PF14265.1 EGC29309.1 - 5.1 7.0 21.9 9.5 6.1 15.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4355) DUF1980 PF09323.5 EGC29309.1 - 5.3 6.7 10.2 25 4.5 7.0 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S46 PF10459.4 EGC29309.1 - 9.4 4.5 12.8 12 4.1 8.9 1.1 1 0 0 1 1 1 0 Peptidase S46 SNARE_assoc PF09335.6 EGC29310.1 - 1.6e-29 102.6 4.0 1.6e-29 102.6 2.8 2.3 3 0 0 3 3 3 1 SNARE associated Golgi protein AdoHcyase PF05221.12 EGC29311.1 - 5.1e-142 471.5 0.1 5.8e-142 471.3 0.1 1.0 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase AdoHcyase_NAD PF00670.16 EGC29311.1 - 7.1e-84 279.5 4.8 1.2e-83 278.8 3.3 1.4 1 0 0 1 1 1 1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 2-Hacid_dh_C PF02826.14 EGC29311.1 - 5.8e-06 25.5 0.1 1.2e-05 24.5 0.1 1.5 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGC29311.1 - 0.0028 17.0 0.5 0.0048 16.2 0.3 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGC29311.1 - 0.0059 16.5 0.1 0.014 15.4 0.1 1.6 1 0 0 1 1 1 1 TrkA-N domain F420_oxidored PF03807.12 EGC29311.1 - 0.028 14.8 0.2 0.069 13.5 0.1 1.7 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent 3HCDH_N PF02737.13 EGC29311.1 - 0.094 12.3 0.5 0.19 11.3 0.4 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDT PF02791.12 EGC29312.1 - 0.085 12.6 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 DDT domain Metallophos PF00149.23 EGC29313.1 - 9.9e-17 60.9 1.3 2.7e-16 59.5 0.9 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGC29313.1 - 1.7e-14 53.6 0.1 4e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EGC29313.1 - 4e-09 35.5 0.9 6.2e-09 34.9 0.6 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EGC29313.1 - 7.7e-06 25.8 0.0 1.6e-05 24.7 0.0 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain fn3 PF00041.16 EGC29313.1 - 0.024 14.7 0.4 0.073 13.2 0.2 1.8 1 0 0 1 1 1 0 Fibronectin type III domain NAD_binding_4 PF07993.7 EGC29314.1 - 1.7e-11 43.5 0.0 3.1e-11 42.6 0.0 1.4 1 1 0 1 1 1 1 Male sterility protein DUF1140 PF06600.6 EGC29315.1 - 0.0086 16.1 1.8 0.0086 16.1 1.3 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF1140) HJURP_C PF12347.3 EGC29315.1 - 0.41 10.2 11.7 0.67 9.5 0.1 3.8 3 1 1 4 4 4 0 Holliday junction regulator protein family C-terminal repeat Sed5p PF11416.3 EGC29315.1 - 0.53 9.7 3.1 0.32 10.4 0.5 2.0 2 0 0 2 2 2 0 Integral membrane protein Sed5p PX PF00787.19 EGC29315.1 - 0.85 9.4 5.9 0.59 9.9 2.1 1.9 1 1 1 2 2 2 0 PX domain FNIP PF05725.7 EGC29316.1 - 2.7e-112 366.5 91.1 3.3e-15 55.7 0.4 14.4 6 4 5 14 14 14 14 FNIP Repeat DUF1769 PF08588.5 EGC29316.1 - 0.0027 17.6 11.4 0.88 9.5 0.2 7.7 6 2 3 9 9 9 1 Protein of unknown function (DUF1769) PXA PF02194.10 EGC29316.1 - 0.097 12.2 0.0 1.4 8.4 0.0 2.3 1 1 1 2 2 2 0 PXA domain Mating_C PF12737.2 EGC29316.1 - 4.5 6.0 7.2 1.5 7.6 0.3 2.2 2 0 0 2 2 2 0 C-terminal domain of homeodomain 1 Syntaxin PF00804.20 EGC29317.1 - 1.3e-15 57.4 4.2 1.3e-15 57.4 2.9 3.0 3 1 0 3 3 3 1 Syntaxin SNARE PF05739.14 EGC29317.1 - 5.9e-12 45.0 1.4 5.9e-12 45.0 0.9 2.1 2 0 0 2 2 2 1 SNARE domain Syntaxin-6_N PF09177.6 EGC29317.1 - 0.0032 17.8 6.8 0.042 14.2 0.6 2.9 2 1 0 2 2 2 2 Syntaxin 6, N-terminal Syntaxin-18_N PF10496.4 EGC29317.1 - 0.83 9.5 12.1 0.53 10.1 0.4 3.9 3 1 0 3 3 3 0 SNARE-complex protein Syntaxin-18 N-terminus DUF1673 PF07895.6 EGC29317.1 - 0.96 8.9 4.3 0.32 10.4 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) Spore_YhcN_YlaJ PF09580.5 EGC29317.1 - 8.8 6.4 12.9 38 4.3 8.9 2.1 1 1 0 1 1 1 0 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) ACOX PF01756.14 EGC29318.1 - 5.6e-21 74.7 0.1 3.7e-20 72.1 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGC29318.1 - 2.1e-09 36.7 0.0 3.7e-09 35.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGC29318.1 - 1.2e-08 35.1 0.0 2.7e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EGC29318.1 - 5.5e-07 29.9 0.0 1.6e-06 28.4 0.0 1.8 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_N PF02771.11 EGC29318.1 - 0.08 13.5 0.0 0.2 12.2 0.0 1.7 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain DUF4395 PF14340.1 EGC29318.1 - 0.14 12.2 0.1 0.78 9.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4395) 3Beta_HSD PF01073.14 EGC29320.1 - 6.8e-19 67.6 0.0 8.7e-19 67.2 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC29320.1 - 3e-18 66.1 0.1 5.1e-18 65.3 0.1 1.4 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGC29320.1 - 7.7e-18 64.3 0.0 2.7e-17 62.5 0.0 1.7 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGC29320.1 - 1.9e-10 41.0 0.0 2.6e-10 40.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Semialdhyde_dh PF01118.19 EGC29320.1 - 2.4e-05 24.6 0.3 0.00014 22.1 0.1 2.1 1 1 1 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EGC29320.1 - 3.7e-05 22.9 0.1 4.6e-05 22.5 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase NmrA PF05368.8 EGC29320.1 - 6.2e-05 22.3 0.1 0.0011 18.3 0.1 2.2 2 0 0 2 2 2 1 NmrA-like family Polysacc_synt_2 PF02719.10 EGC29320.1 - 0.00012 21.0 0.5 0.00022 20.2 0.4 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein DapB_N PF01113.15 EGC29320.1 - 0.0093 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus Ldh_1_N PF00056.18 EGC29320.1 - 0.02 14.6 0.2 0.046 13.5 0.1 1.6 1 0 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain KR PF08659.5 EGC29320.1 - 0.052 13.2 0.0 0.24 11.0 0.0 1.9 1 1 0 1 1 1 0 KR domain YccJ PF13993.1 EGC29320.1 - 0.073 13.1 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 YccJ-like protein SpoU_methylase PF00588.14 EGC29321.1 - 5.1e-34 117.1 0.0 7.1e-34 116.7 0.0 1.2 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EGC29321.1 - 7.6e-07 29.2 0.1 1.5e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.4 EGC29321.1 - 0.018 14.5 0.0 0.032 13.7 0.0 1.5 2 0 0 2 2 2 0 SAM-dependent RNA methyltransferase CAP PF00188.21 EGC29322.1 - 7.3e-13 49.0 8.5 7.3e-13 49.0 5.9 1.6 2 0 0 2 2 2 1 Cysteine-rich secretory protein family DEAD PF00270.24 EGC29323.1 - 7.4e-35 119.9 0.1 2e-34 118.5 0.0 1.7 2 1 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC29323.1 - 4.7e-21 74.4 0.2 9.8e-21 73.4 0.1 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC29323.1 - 8.5e-07 28.9 0.0 2e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGC29323.1 - 9.4e-05 21.5 0.1 0.00018 20.7 0.1 1.4 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EGC29323.1 - 0.026 14.2 0.0 0.064 13.0 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain AAA_30 PF13604.1 EGC29323.1 - 0.18 11.3 0.0 0.37 10.3 0.0 1.5 1 1 0 1 1 1 0 AAA domain Dynactin_p22 PF07426.6 EGC29324.1 - 9.7e-08 31.4 11.9 2.1e-06 27.1 7.6 2.4 1 1 1 2 2 2 1 Dynactin subunit p22 UPF0227 PF05728.7 EGC29324.1 - 0.036 13.7 0.5 0.069 12.8 0.3 1.6 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0227) DUF3333 PF11812.3 EGC29324.1 - 0.069 13.1 2.7 0.048 13.6 0.7 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3333) DUF4320 PF14208.1 EGC29324.1 - 0.15 11.9 2.9 0.085 12.8 0.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4320) Mit_KHE1 PF10173.4 EGC29324.1 - 0.35 10.6 7.6 0.57 10.0 5.3 1.5 1 1 0 1 1 1 0 Mitochondrial K+-H+ exchange-related RE_HindIII PF09518.5 EGC29324.1 - 0.69 8.7 10.9 0.35 9.7 2.1 2.6 1 1 1 2 2 2 0 HindIII restriction endonuclease UBN2 PF14223.1 EGC29324.1 - 0.91 9.3 9.1 0.68 9.7 1.0 3.2 2 1 0 3 3 3 0 gag-polypeptide of LTR copia-type DUF2360 PF10152.4 EGC29324.1 - 1.2 9.4 7.7 0.39 10.9 1.2 2.2 1 1 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) FlaG PF03646.10 EGC29324.1 - 1.9 8.6 9.7 3.3 7.8 2.5 2.5 2 1 0 2 2 2 0 FlaG protein DUF2762 PF10960.3 EGC29324.1 - 2.8 7.7 6.9 33 4.2 0.7 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2762) Vac_Fusion PF02346.11 EGC29324.1 - 6.7 6.2 6.7 50 3.4 0.1 3.8 4 0 0 4 4 4 0 Chordopoxvirus fusion protein GATA PF00320.22 EGC29325.1 - 8.4e-15 53.8 4.8 8.4e-15 53.8 3.3 2.1 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.2 EGC29325.1 - 1.5 8.7 7.6 6.7 6.6 0.5 2.8 2 1 0 2 2 2 0 Double zinc ribbon C1_1 PF00130.17 EGC29325.1 - 4.9 6.9 7.6 1.2 8.9 1.0 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Abhydrolase_6 PF12697.2 EGC29326.1 - 5.7e-10 39.4 0.0 6.2e-10 39.3 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC29326.1 - 2.1e-09 37.3 0.0 2.9e-09 36.8 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC29326.1 - 0.00038 20.2 0.0 0.00044 20.0 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EGC29326.1 - 0.023 13.7 0.1 0.041 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) UPF0020 PF01170.13 EGC29326.1 - 0.035 13.6 0.0 0.056 13.0 0.0 1.2 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 PH PF00169.24 EGC29327.1 - 4.7e-09 36.3 2.0 1.6e-08 34.7 1.4 1.9 1 0 0 1 1 1 1 PH domain PH_3 PF14593.1 EGC29327.1 - 5.4e-07 29.4 3.1 1.3e-06 28.2 2.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC29327.1 - 0.0047 17.1 4.1 0.025 14.8 2.8 2.4 1 1 0 1 1 1 1 Pleckstrin homology domain ENOD93 PF03386.9 EGC29328.1 - 0.025 14.3 0.0 0.033 13.8 0.0 1.1 1 0 0 1 1 1 0 Early nodulin 93 ENOD93 protein DUF2076 PF09849.4 EGC29328.1 - 0.083 12.9 0.0 0.14 12.2 0.0 1.4 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) DUF1304 PF06993.7 EGC29328.1 - 0.085 12.5 0.0 0.11 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1304) Tmemb_185A PF10269.4 EGC29329.1 - 2.3e-31 109.2 30.8 4.7e-31 108.2 18.5 2.0 1 1 1 2 2 2 2 Transmembrane Fragile-X-F protein DUF872 PF05915.7 EGC29329.1 - 0.078 12.8 9.0 1 9.2 0.0 3.6 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4014 PF13198.1 EGC29329.1 - 0.1 13.0 0.4 0.1 13.0 0.3 2.8 3 1 0 4 4 4 0 Protein of unknown function (DUF4014) DUF3040 PF11239.3 EGC29329.1 - 0.51 10.4 0.0 0.51 10.4 0.0 2.9 3 1 1 4 4 4 0 Protein of unknown function (DUF3040) PBP1_TM PF14812.1 EGC29329.1 - 2.9 8.2 10.4 4.9 7.5 0.0 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF846 PF05832.7 EGC29330.1 - 1.3e-50 170.7 14.2 1.7e-50 170.4 9.8 1.1 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) HR_lesion PF05514.6 EGC29330.1 - 0.047 13.5 2.0 0.4 10.4 0.1 2.2 2 0 0 2 2 2 0 HR-like lesion-inducing Herpes_gE PF02480.11 EGC29330.1 - 0.055 11.7 0.1 3.1 5.9 0.3 2.0 2 0 0 2 2 2 0 Alphaherpesvirus glycoprotein E Renin_r PF07850.9 EGC29330.1 - 1 9.7 4.6 3.8 7.9 0.0 2.3 2 0 0 2 2 2 0 Renin receptor-like protein AMP-binding PF00501.23 EGC29331.1 - 5.3e-74 249.0 0.0 6.7e-74 248.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC29331.1 - 7.9e-18 65.1 0.0 1.6e-17 64.2 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DbpA PF03880.10 EGC29331.1 - 0.11 12.1 0.2 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 DbpA RNA binding domain HATPase_c PF02518.21 EGC29332.1 - 4.1e-24 84.4 0.1 9.4e-24 83.2 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC29332.1 - 1.2e-19 70.3 0.0 3.5e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGC29332.1 - 3.3e-18 65.4 0.0 6.9e-18 64.4 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EGC29332.1 - 0.00014 22.2 0.9 0.00029 21.1 0.0 2.0 2 0 0 2 2 2 1 PAS domain FKS1_dom1 PF14288.1 EGC29332.1 - 0.011 15.6 0.2 0.037 13.9 0.2 1.9 1 0 0 1 1 1 0 1,3-beta-glucan synthase subunit FKS1, domain-1 HATPase_c_3 PF13589.1 EGC29332.1 - 0.037 13.6 0.1 0.037 13.6 0.0 2.3 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase PAS PF00989.19 EGC29332.1 - 0.12 12.2 0.8 1.1 9.0 0.0 2.8 2 1 0 2 2 2 0 PAS fold DUF4050 PF13259.1 EGC29334.1 - 1e-05 25.4 7.4 1.3e-05 25.1 5.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF4050) JmjC PF02373.17 EGC29334.1 - 0.031 14.4 0.7 0.036 14.2 0.5 1.1 1 0 0 1 1 1 0 JmjC domain, hydroxylase IL1_propep PF02394.11 EGC29334.1 - 0.058 13.7 0.2 0.069 13.5 0.1 1.0 1 0 0 1 1 1 0 Interleukin-1 propeptide PNTB PF02233.11 EGC29335.1 - 2.6e-178 593.5 14.4 2.6e-178 593.5 10.0 2.3 2 0 0 2 2 2 1 NAD(P) transhydrogenase beta subunit AlaDh_PNT_C PF01262.16 EGC29335.1 - 2.8e-55 186.4 3.1 2.9e-55 186.4 0.8 2.1 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain AlaDh_PNT_N PF05222.10 EGC29335.1 - 2.3e-45 153.9 0.4 4.5e-45 152.9 0.3 1.5 1 0 0 1 1 1 1 Alanine dehydrogenase/PNT, N-terminal domain DUF3814 PF12769.2 EGC29335.1 - 6.4e-32 109.5 5.8 6.4e-32 109.5 4.0 3.7 2 1 1 3 3 3 1 Domain of unknown function (DUF3814) 2-Hacid_dh_C PF02826.14 EGC29335.1 - 0.00029 20.0 1.0 0.48 9.5 0.1 3.4 3 0 0 3 3 3 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EGC29335.1 - 0.021 14.3 0.3 0.085 12.4 0.2 2.1 1 0 0 1 1 1 0 Zinc-binding dehydrogenase Methyltransf_31 PF13847.1 EGC29335.1 - 0.033 13.7 0.0 0.11 12.0 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain TPP_enzyme_M PF00205.17 EGC29335.1 - 0.049 13.3 0.1 1.4 8.6 0.0 2.7 2 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain TIG PF01833.19 EGC29336.1 - 3e-07 30.3 25.3 1e-05 25.4 0.8 5.1 4 1 0 4 4 4 2 IPT/TIG domain hEGF PF12661.2 EGC29336.1 - 0.0034 17.3 7.2 0.019 15.0 5.0 2.4 1 0 0 1 1 1 1 Human growth factor-like EGF EGF_2 PF07974.8 EGC29336.1 - 0.0046 17.0 57.3 0.14 12.3 9.5 3.9 3 1 1 4 4 4 3 EGF-like domain Laminin_EGF PF00053.19 EGC29336.1 - 0.57 10.1 39.1 0.68 9.9 5.4 3.8 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) FKBP_C PF00254.23 EGC29337.1 - 1.2e-10 41.2 0.0 4.2e-10 39.5 0.0 2.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Act-Frag_cataly PF09192.5 EGC29338.1 - 5.8e-88 294.4 18.3 5.8e-88 294.4 12.7 1.7 1 1 0 1 1 1 1 Actin-fragmin kinase, catalytic SR-25 PF10500.4 EGC29338.1 - 3 7.2 15.3 5.6 6.3 10.6 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein MIP PF00230.15 EGC29340.1 - 4.7e-49 166.8 19.6 9.8e-34 116.7 5.4 2.0 2 0 0 2 2 2 2 Major intrinsic protein Bestrophin PF01062.16 EGC29340.1 - 0.031 13.2 0.9 0.67 8.8 0.1 2.2 2 0 0 2 2 2 0 Bestrophin, RFP-TM, chloride channel zf-CCHC PF00098.18 EGC29341.1 - 0.0052 16.6 2.9 0.0087 15.9 2.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGC29341.1 - 0.014 14.9 0.5 0.03 13.8 0.4 1.5 1 0 0 1 1 1 0 Zinc knuckle Med4 PF10018.4 EGC29342.1 - 6.7e-31 107.1 2.0 6.7e-31 107.1 1.4 2.3 2 0 0 2 2 2 1 Vitamin-D-receptor interacting Mediator subunit 4 Fungal_trans_2 PF11951.3 EGC29342.1 - 0.0048 15.5 4.4 0.0069 15.0 3.1 1.2 1 0 0 1 1 1 1 Fungal specific transcription factor domain Sigma70_ner PF04546.8 EGC29342.1 - 0.037 13.6 17.1 0.096 12.2 4.8 2.3 2 0 0 2 2 2 0 Sigma-70, non-essential region TSA PF03249.8 EGC29342.1 - 0.059 11.9 16.7 0.085 11.3 11.6 1.2 1 0 0 1 1 1 0 Type specific antigen Med15 PF09606.5 EGC29342.1 - 0.19 9.8 36.4 0.12 10.5 16.5 2.1 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal FimP PF09766.4 EGC29342.1 - 0.34 9.9 26.6 0.038 13.0 1.7 2.6 3 0 0 3 3 3 0 Fms-interacting protein Serinc PF03348.10 EGC29342.1 - 2.2 6.8 5.7 2.8 6.5 3.9 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) hDGE_amylase PF14701.1 EGC29342.1 - 5.3 5.8 11.1 7.8 5.2 7.7 1.2 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Ctr PF04145.10 EGC29342.1 - 5.7 6.9 6.7 9.2 6.3 4.4 1.5 1 1 0 1 1 1 0 Ctr copper transporter family DUF4175 PF13779.1 EGC29342.1 - 5.9 4.4 25.0 8.6 3.9 17.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF498 PF04430.9 EGC29343.1 - 1.4e-25 88.9 0.0 2.2e-25 88.3 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF498/DUF598) SPT6_acidic PF14632.1 EGC29343.1 - 3.4 7.8 8.4 2.5 8.3 4.6 1.6 1 1 0 1 1 1 0 Acidic N-terminal SPT6 YchF-GTPase_C PF06071.8 EGC29344.1 - 4.3e-33 112.9 0.2 8.8e-33 111.9 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGC29344.1 - 4.6e-20 71.7 0.2 1.5e-19 70.0 0.0 1.9 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC29344.1 - 1.4e-07 30.9 0.0 3.1e-07 29.7 0.0 1.7 1 0 0 1 1 1 1 Ferrous iron transport protein B ArgK PF03308.11 EGC29344.1 - 0.0019 17.0 0.0 0.0035 16.1 0.0 1.4 1 0 0 1 1 1 1 ArgK protein AAA_17 PF13207.1 EGC29344.1 - 0.015 16.1 0.0 0.85 10.4 0.0 2.7 3 1 0 3 3 3 0 AAA domain Dopey_N PF04118.9 EGC29344.1 - 0.045 12.5 0.2 0.08 11.6 0.1 1.3 1 0 0 1 1 1 0 Dopey, N-terminal Dynamin_N PF00350.18 EGC29344.1 - 0.092 12.5 1.2 11 5.8 0.1 2.7 1 1 2 3 3 3 0 Dynamin family Pkinase PF00069.20 EGC29345.1 - 1.3e-70 237.4 0.0 2.5e-70 236.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29345.1 - 1.8e-49 168.1 0.0 2.5e-49 167.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase DUF3543 PF12063.3 EGC29345.1 - 1.6e-08 34.0 0.5 4.9e-08 32.4 0.2 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3543) MIT PF04212.13 EGC29345.1 - 0.00033 20.4 1.1 0.0013 18.5 0.5 2.1 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain APH PF01636.18 EGC29345.1 - 0.0015 18.3 0.0 0.0071 16.1 0.0 1.8 1 1 1 2 2 2 1 Phosphotransferase enzyme family DUF605 PF04652.11 EGC29345.1 - 0.012 15.0 12.2 0.018 14.4 8.5 1.2 1 0 0 1 1 1 0 Vta1 like Phage_connect_1 PF05135.8 EGC29345.1 - 0.025 14.7 1.0 9.6 6.4 0.1 2.8 2 0 0 2 2 2 0 Phage gp6-like head-tail connector protein LRR_9 PF14580.1 EGC29346.1 - 5.5e-07 29.3 0.1 1e-06 28.4 0.1 1.4 1 0 0 1 1 1 1 Leucine-rich repeat LRR_4 PF12799.2 EGC29346.1 - 8.2e-06 25.3 6.0 0.0026 17.3 1.9 3.2 2 1 1 3 3 3 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC29346.1 - 1.9e-05 24.3 0.7 1.9e-05 24.3 0.5 2.4 3 0 0 3 3 3 1 Leucine rich repeat LRR_1 PF00560.28 EGC29346.1 - 0.2 11.8 6.2 0.67 10.2 0.0 3.6 4 0 0 4 4 4 0 Leucine Rich Repeat LRR_6 PF13516.1 EGC29346.1 - 0.48 10.6 3.9 23 5.4 0.1 3.4 3 0 0 3 3 3 0 Leucine Rich repeat Trypan_PARP PF05887.6 EGC29347.1 - 0.24 11.2 29.2 0.38 10.5 20.3 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF605 PF04652.11 EGC29347.1 - 0.65 9.3 33.1 0.88 8.9 23.0 1.1 1 0 0 1 1 1 0 Vta1 like DUF2413 PF10310.4 EGC29347.1 - 2.1 7.0 6.9 2.9 6.6 4.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RNA_pol_Rpb1_5 PF04998.12 EGC29348.1 - 2.6e-96 322.1 0.0 3e-94 315.3 0.0 3.1 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGC29348.1 - 1.5e-59 200.6 0.5 5e-59 198.9 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGC29348.1 - 2.8e-33 114.8 0.0 8.5e-33 113.3 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_1 PF04997.7 EGC29348.1 - 3.8e-30 105.3 2.3 3.8e-30 105.3 1.6 3.7 2 2 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_4 PF05000.12 EGC29348.1 - 9e-22 76.8 0.0 9e-22 76.8 0.0 3.4 4 0 0 4 4 4 1 RNA polymerase Rpb1, domain 4 EF-hand_8 PF13833.1 EGC29348.1 - 0.025 14.2 0.9 6.1 6.5 0.0 3.1 3 0 0 3 3 3 0 EF-hand domain pair NAF PF03822.9 EGC29349.1 - 0.15 11.7 0.2 0.15 11.7 0.1 3.2 4 0 0 4 4 4 0 NAF domain Mito_fiss_reg PF05308.6 EGC29350.1 - 0.36 10.1 5.6 0.49 9.7 3.9 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator HMG_CoA_synt_N PF01154.12 EGC29353.1 - 2.8e-89 297.2 0.7 4.2e-89 296.6 0.5 1.3 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal HMG_CoA_synt_C PF08540.5 EGC29353.1 - 3.2e-88 295.8 4.7 4.2e-88 295.4 3.3 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal MIP-T3 PF10243.4 EGC29355.1 - 0.5 8.7 69.9 0.99 7.7 48.4 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Phospholamban PF04272.9 EGC29355.1 - 0.89 9.0 0.0 0.89 9.0 0.0 2.4 3 0 0 3 3 3 0 Phospholamban Plasmodium_HRP PF05403.6 EGC29355.1 - 2 7.9 29.8 0.041 13.4 15.0 1.9 1 1 1 2 2 2 0 Plasmodium histidine-rich protein (HRPII/III) DUF2419 PF10343.4 EGC29356.1 - 1.6e-32 112.9 0.3 8.1e-32 110.6 0.2 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1084 PF06454.6 EGC29357.1 - 0.0006 18.9 13.6 0.00093 18.3 9.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) EGF_2 PF07974.8 EGC29357.1 - 0.046 13.8 14.8 0.094 12.9 10.3 1.5 1 0 0 1 1 1 0 EGF-like domain Zip PF02535.17 EGC29357.1 - 0.26 10.2 6.2 0.15 11.0 2.7 1.8 1 1 1 2 2 2 0 ZIP Zinc transporter NTP_transf_2 PF01909.18 EGC29358.1 - 1.2e-07 31.9 0.0 4.1e-07 30.2 0.0 2.1 1 0 0 1 1 1 1 Nucleotidyltransferase domain PAP_assoc PF03828.14 EGC29358.1 - 4e-07 29.8 0.1 4e-07 29.8 0.1 2.8 3 0 0 3 3 3 1 Cid1 family poly A polymerase FNIP PF05725.7 EGC29359.1 - 5.7e-68 224.6 44.9 1.3e-11 44.2 0.0 12.9 8 1 6 14 14 14 13 FNIP Repeat KTSC PF13619.1 EGC29359.1 - 0.0025 17.3 0.0 2 8.0 0.0 3.7 4 0 0 4 4 4 2 KTSC domain LRR_8 PF13855.1 EGC29359.1 - 0.32 10.7 16.5 0.63 9.8 0.8 5.8 5 1 1 6 6 6 0 Leucine rich repeat Beach PF02138.13 EGC29360.1 - 4.6e-111 370.5 1.3 4.6e-111 370.5 0.9 3.0 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EGC29360.1 - 8.5e-19 67.3 0.0 5.1e-18 64.8 0.0 2.5 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EGC29360.1 - 2.8e-12 46.0 16.3 3e-06 26.8 1.6 6.4 6 0 0 6 6 6 4 WD domain, G-beta repeat TIG PF01833.19 EGC29361.1 - 7.8e-21 73.8 41.1 1.9e-06 27.7 0.6 7.1 6 1 1 7 7 7 4 IPT/TIG domain DUF4448 PF14610.1 EGC29361.1 - 0.0013 18.2 0.0 0.0038 16.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EGC29361.1 - 0.03 14.0 0.2 0.19 11.4 0.0 2.1 2 0 0 2 2 2 0 TMEM154 protein family CBM_20 PF00686.14 EGC29362.1 - 7.8e-19 67.0 2.4 1.2e-18 66.4 1.5 1.4 1 1 0 1 1 1 1 Starch binding domain CBM_48 PF02922.13 EGC29362.1 - 0.085 12.9 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Pkinase PF00069.20 EGC29363.1 - 3.9e-12 45.8 0.4 9.7e-12 44.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29363.1 - 0.0011 18.1 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase DUF4606 PF15379.1 EGC29363.1 - 0.066 13.2 0.1 0.17 12.0 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4606) DUF603 PF04645.7 EGC29364.1 - 0.11 12.3 2.6 0.14 12.1 1.8 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Reo_sigmaC PF04582.7 EGC29365.1 - 1.2 8.2 9.8 2.4 7.2 3.0 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DivIVA PF05103.8 EGC29365.1 - 2.3 8.3 39.1 0.04 13.9 13.6 2.2 2 0 0 2 2 2 0 DivIVA protein IncA PF04156.9 EGC29365.1 - 3.2 7.3 53.0 2.5 7.6 19.0 2.1 1 1 1 2 2 2 0 IncA protein DUF3584 PF12128.3 EGC29365.1 - 4 4.6 36.2 5.1 4.2 25.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Cas_GSU0053 PF09617.5 EGC29365.1 - 4.9 6.9 7.8 11 5.7 0.7 2.4 1 1 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) APG6 PF04111.7 EGC29365.1 - 6.4 5.7 49.2 3.4 6.6 15.2 2.1 1 1 1 2 2 2 0 Autophagy protein Apg6 DUF948 PF06103.6 EGC29365.1 - 6.4 6.7 16.4 1.2 8.9 3.2 2.9 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Melibiase PF02065.13 EGC29366.1 - 6.9e-16 57.9 0.2 3.1e-14 52.4 0.0 2.2 1 1 1 2 2 2 2 Melibiase ACT_4 PF13291.1 EGC29366.1 - 0.043 14.1 0.3 0.084 13.2 0.2 1.4 1 0 0 1 1 1 0 ACT domain Vps52 PF04129.7 EGC29367.1 - 4.5e-71 239.9 28.5 1.4e-70 238.2 19.8 1.7 1 1 0 1 1 1 1 Vps52 / Sac2 family Sec3_C PF09763.4 EGC29367.1 - 6.6e-06 24.5 24.0 6.6e-06 24.5 16.6 2.4 1 1 1 2 2 2 2 Exocyst complex component Sec3 Tmemb_185A PF10269.4 EGC29368.1 - 1.3e-32 113.3 15.1 1.3e-32 113.3 10.5 1.7 1 1 0 1 1 1 1 Transmembrane Fragile-X-F protein DnaJ PF00226.26 EGC29368.1 - 2.1e-27 94.6 1.4 3.4e-27 93.9 1.0 1.4 1 0 0 1 1 1 1 DnaJ domain MFS_1 PF07690.11 EGC29368.1 - 1.3 7.6 29.1 0.35 9.5 3.4 2.5 2 1 0 2 2 2 0 Major Facilitator Superfamily DUF3595 PF12166.3 EGC29368.1 - 7.4 5.2 10.0 6.6 5.4 2.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF3595) DUF1128 PF06569.6 EGC29369.1 - 0.059 13.0 0.8 0.22 11.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1128) Daxx PF03344.10 EGC29371.1 - 0.00019 20.0 26.2 0.0002 19.9 18.1 1.1 1 0 0 1 1 1 1 Daxx Family BUD22 PF09073.5 EGC29371.1 - 0.0017 17.5 18.7 0.0018 17.4 13.0 1.2 1 0 0 1 1 1 1 BUD22 Nop14 PF04147.7 EGC29371.1 - 0.0026 15.7 26.3 0.0028 15.6 18.2 1.1 1 0 0 1 1 1 1 Nop14-like family Spore_coat_CotO PF14153.1 EGC29371.1 - 0.0031 16.9 13.9 0.0035 16.8 9.6 1.3 1 0 0 1 1 1 1 Spore coat protein CotO VID27 PF08553.5 EGC29371.1 - 0.03 12.5 21.0 0.036 12.3 14.5 1.1 1 0 0 1 1 1 0 VID27 cytoplasmic protein PCNA_N PF00705.13 EGC29371.1 - 0.03 13.8 0.2 0.13 11.8 0.0 2.0 2 0 0 2 2 2 0 Proliferating cell nuclear antigen, N-terminal domain UPF0560 PF10577.4 EGC29371.1 - 0.031 12.5 6.4 0.036 12.3 4.4 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4045 PF13254.1 EGC29371.1 - 0.045 13.0 9.0 0.059 12.6 6.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) Ycf1 PF05758.7 EGC29371.1 - 0.052 11.2 14.9 0.054 11.2 10.3 1.3 1 0 0 1 1 1 0 Ycf1 SprA-related PF12118.3 EGC29371.1 - 0.15 11.4 12.9 0.18 11.0 8.9 1.2 1 0 0 1 1 1 0 SprA-related family CobT PF06213.7 EGC29371.1 - 0.15 11.1 27.2 0.19 10.8 18.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT CDC45 PF02724.9 EGC29371.1 - 0.24 9.3 21.1 0.3 9.0 14.6 1.1 1 0 0 1 1 1 0 CDC45-like protein HSP90 PF00183.13 EGC29371.1 - 0.28 9.5 24.2 0.38 9.0 16.8 1.2 1 0 0 1 1 1 0 Hsp90 protein TraH_2 PF06871.6 EGC29371.1 - 0.28 10.5 4.4 0.42 10.0 3.0 1.3 1 0 0 1 1 1 0 TraH_2 DUF1510 PF07423.6 EGC29371.1 - 0.29 10.4 25.0 0.44 9.8 17.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SID-1_RNA_chan PF13965.1 EGC29371.1 - 0.3 9.1 3.7 0.37 8.8 2.5 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 RR_TM4-6 PF06459.7 EGC29371.1 - 0.38 10.6 20.4 0.49 10.2 14.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 RRN3 PF05327.6 EGC29371.1 - 0.46 8.5 13.1 0.56 8.2 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Mpp10 PF04006.7 EGC29371.1 - 0.49 8.6 35.0 0.69 8.2 24.2 1.1 1 0 0 1 1 1 0 Mpp10 protein Band_3_cyto PF07565.8 EGC29371.1 - 0.55 9.6 5.1 0.73 9.2 3.5 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain TRAP_alpha PF03896.11 EGC29371.1 - 0.7 8.8 17.8 1.1 8.2 12.3 1.5 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF2722 PF10846.3 EGC29371.1 - 0.83 8.6 9.7 0.97 8.3 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2722) DDHD PF02862.12 EGC29371.1 - 0.87 9.3 9.6 1.3 8.8 6.6 1.3 1 0 0 1 1 1 0 DDHD domain DUF2457 PF10446.4 EGC29371.1 - 0.9 8.1 26.2 1.2 7.8 18.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) SDA1 PF05285.7 EGC29371.1 - 0.99 8.6 28.4 1.1 8.4 19.7 1.1 1 0 0 1 1 1 0 SDA1 AAA_11 PF13086.1 EGC29371.1 - 1.2 8.6 4.5 1.5 8.3 3.1 1.2 1 0 0 1 1 1 0 AAA domain NOA36 PF06524.7 EGC29371.1 - 2.1 7.5 16.9 3.1 6.9 11.7 1.3 1 0 0 1 1 1 0 NOA36 protein Pilt PF15453.1 EGC29371.1 - 2.6 7.6 11.5 3.1 7.3 8.0 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Zip PF02535.17 EGC29371.1 - 2.9 6.8 7.1 3.6 6.5 4.9 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter CENP-T PF15511.1 EGC29371.1 - 3.2 6.8 20.8 4.2 6.4 14.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Adeno_terminal PF02459.10 EGC29371.1 - 4.1 5.4 16.4 6.6 4.7 11.4 1.3 1 0 0 1 1 1 0 Adenoviral DNA terminal protein Sporozoite_P67 PF05642.6 EGC29371.1 - 5 4.8 12.7 8.1 4.1 8.8 1.5 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Paf1 PF03985.8 EGC29371.1 - 8 5.0 32.7 11 4.5 22.7 1.2 1 0 0 1 1 1 0 Paf1 COPI_C PF06957.6 EGC29371.1 - 8.4 4.8 12.4 12 4.2 8.6 1.2 1 0 0 1 1 1 0 Coatomer (COPI) alpha subunit C-terminus DUF2201_N PF13203.1 EGC29371.1 - 9.1 5.3 7.7 11 5.0 5.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Resolvase PF00239.16 EGC29373.1 - 1.2e-06 28.4 0.0 9e-06 25.6 0.0 2.3 2 0 0 2 2 2 1 Resolvase, N terminal domain Med25_SD1 PF11235.3 EGC29373.1 - 0.012 15.8 2.6 0.025 14.8 1.8 1.4 1 0 0 1 1 1 0 Mediator complex subunit 25 synapsin 1 Sld5 PF05916.6 EGC29373.1 - 0.06 13.6 0.8 0.14 12.4 0.1 2.0 2 0 0 2 2 2 0 GINS complex protein Med3 PF11593.3 EGC29373.1 - 0.19 10.9 13.4 0.44 9.7 9.3 1.5 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal DUF3275 PF11679.3 EGC29373.1 - 3.2 7.3 4.8 5.8 6.4 3.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Mucin PF01456.12 EGC29373.1 - 4.6 7.0 24.5 9.5 5.9 17.0 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_transf_10 PF00852.14 EGC29375.1 - 3.3e-17 62.0 2.6 1.4e-16 60.0 1.8 1.7 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) ArdA PF07275.6 EGC29375.1 - 0.081 13.1 0.1 0.088 13.0 0.0 1.2 1 0 0 1 1 1 0 Antirestriction protein (ArdA) ABC2_membrane_2 PF12679.2 EGC29377.1 - 0.022 13.6 2.1 0.029 13.2 1.4 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein FA_desaturase PF00487.19 EGC29377.1 - 0.03 13.7 0.3 0.03 13.7 0.2 1.1 1 0 0 1 1 1 0 Fatty acid desaturase DUF3487 PF11990.3 EGC29377.1 - 0.04 13.3 2.6 0.065 12.6 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) DUF4131 PF13567.1 EGC29377.1 - 0.11 11.9 0.7 0.13 11.6 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3357 PF11837.3 EGC29377.1 - 0.13 12.1 2.5 0.23 11.3 1.8 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4179 PF13786.1 EGC29377.1 - 0.34 11.1 6.7 0.57 10.4 1.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4179) RasGAP PF00616.14 EGC29378.1 - 4.3e-45 153.8 4.0 4.3e-45 153.8 2.8 3.0 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGC29378.1 - 8.9e-24 83.7 11.6 8.9e-24 83.7 8.0 3.6 2 1 0 2 2 2 1 RasGAP C-terminus WD40 PF00400.27 EGC29380.1 - 0.016 15.0 2.2 0.093 12.6 0.2 2.7 3 0 0 3 3 3 0 WD domain, G-beta repeat zf-TFIIIC PF12660.2 EGC29381.1 - 4.8e-07 29.5 4.8 4.8e-07 29.5 3.3 1.7 2 0 0 2 2 2 1 Putative zinc-finger of transcription factor IIIC complex PyrI_C PF02748.10 EGC29381.1 - 0.0014 18.0 12.1 0.063 12.7 3.0 3.4 3 0 0 3 3 3 2 Aspartate carbamoyltransferase regulatory chain, metal binding domain DZR PF12773.2 EGC29381.1 - 0.15 11.8 9.4 1.8 8.4 4.0 3.2 3 1 1 4 4 4 0 Double zinc ribbon Cytochrome_C7 PF14522.1 EGC29381.1 - 0.29 10.8 2.0 0.54 9.9 0.8 2.1 1 1 0 1 1 1 0 Cytochrome c7 zf-CHCC PF10276.4 EGC29381.1 - 0.86 9.5 5.7 10 6.0 0.1 3.3 3 0 0 3 3 3 0 Zinc-finger domain zf-C3HC4_3 PF13920.1 EGC29381.1 - 0.86 9.3 9.5 22 4.8 0.0 3.6 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-RING_3 PF14369.1 EGC29381.1 - 1.1 9.2 8.0 0.73 9.8 0.5 3.2 3 0 0 3 3 3 0 zinc-finger zf-FCS PF06467.9 EGC29381.1 - 8.1 6.1 12.0 8 6.1 0.4 4.2 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif DNA_RNApol_7kD PF03604.8 EGC29381.1 - 8.1 6.0 9.6 3.3 7.2 1.8 2.7 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit zinc-ribbons_6 PF07191.7 EGC29381.1 - 8.8 6.1 8.0 4.7 7.0 2.1 2.9 2 1 1 3 3 3 0 zinc-ribbons TPR_11 PF13414.1 EGC29382.1 - 3.5e-22 77.8 8.5 5.9e-15 54.6 1.6 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC29382.1 - 2.9e-14 51.7 5.9 5.1e-05 22.8 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGC29382.1 - 6e-13 47.7 8.3 0.00014 21.3 0.1 3.3 3 0 0 3 3 3 3 Tetratricopeptide repeat zf-C3HC4 PF00097.20 EGC29382.1 - 1.2e-07 31.2 14.3 1.2e-07 31.2 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29382.1 - 2.3e-07 30.7 14.8 6e-07 29.3 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC29382.1 - 6.5e-07 29.0 13.8 1.4e-06 28.0 9.5 1.6 1 0 0 1 1 1 1 Ring finger domain TPR_16 PF13432.1 EGC29382.1 - 6.7e-07 29.8 0.2 1.3e-05 25.6 0.0 2.2 1 1 1 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC29382.1 - 1.3e-06 28.4 4.6 2.9e-06 27.2 3.2 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 zf-C3HC4_3 PF13920.1 EGC29382.1 - 2.7e-06 26.9 10.7 6.2e-06 25.7 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_17 PF13431.1 EGC29382.1 - 3.9e-06 26.6 6.3 0.055 13.6 0.0 4.1 3 1 1 4 4 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC29382.1 - 4.9e-06 26.3 1.6 0.0018 18.1 0.4 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat zf-RING_5 PF14634.1 EGC29382.1 - 6.1e-06 25.8 14.6 1.6e-05 24.5 10.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain TPR_8 PF13181.1 EGC29382.1 - 0.00014 21.3 9.9 0.0057 16.3 0.1 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC29382.1 - 0.00034 20.8 0.0 0.049 13.9 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat zf-C3HC4_4 PF15227.1 EGC29382.1 - 0.0015 18.4 16.0 0.003 17.3 11.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING TPR_14 PF13428.1 EGC29382.1 - 0.0032 17.9 0.0 0.48 11.1 0.0 2.8 2 1 1 3 3 2 1 Tetratricopeptide repeat zf-RING_6 PF14835.1 EGC29382.1 - 0.0045 16.7 8.3 0.0093 15.7 5.8 1.4 1 0 0 1 1 1 1 zf-RING of BARD1-type protein TPR_6 PF13174.1 EGC29382.1 - 0.0053 17.1 1.2 1.1 9.8 0.1 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat NARP1 PF12569.3 EGC29382.1 - 0.015 14.0 0.2 0.033 12.9 0.1 1.5 1 1 0 1 1 1 0 NMDA receptor-regulated protein 1 zf-RING_UBOX PF13445.1 EGC29382.1 - 0.047 13.4 10.8 0.17 11.6 7.5 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGC29382.1 - 0.049 13.2 12.4 0.14 11.7 8.6 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_9 PF13371.1 EGC29382.1 - 0.071 12.9 0.2 0.5 10.2 0.4 2.0 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF3808 PF10300.4 EGC29382.1 - 0.087 11.3 0.4 0.14 10.7 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) Rad50_zn_hook PF04423.9 EGC29382.1 - 1.6 8.2 4.9 7.7 6.0 1.1 3.0 3 0 0 3 3 3 0 Rad50 zinc hook motif RhoGEF PF00621.15 EGC29383.1 - 3.3e-42 144.4 0.5 3.3e-42 144.4 0.3 3.7 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.24 EGC29383.1 - 2.9e-05 24.2 3.0 4.4e-05 23.6 0.3 2.7 2 0 0 2 2 2 1 PH domain IQ PF00612.22 EGC29383.1 - 0.00021 20.6 0.1 0.00041 19.7 0.0 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif zf-C2H2_4 PF13894.1 EGC29383.1 - 0.052 13.9 0.3 0.15 12.4 0.2 1.9 1 0 0 1 1 1 0 C2H2-type zinc finger Erf4 PF10256.4 EGC29384.1 - 1.8e-08 34.2 1.4 2.5e-06 27.3 0.9 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4131 PF13567.1 EGC29384.1 - 0.041 13.2 0.6 0.057 12.8 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Git3_C PF11970.3 EGC29384.1 - 0.053 13.2 0.2 0.12 12.1 0.1 1.6 1 0 0 1 1 1 0 G protein-coupled glucose receptor regulating Gpa2 C-term DUF4191 PF13829.1 EGC29384.1 - 0.092 11.8 0.2 0.13 11.3 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) IncA PF04156.9 EGC29384.1 - 0.1 12.1 0.0 0.16 11.5 0.0 1.3 1 0 0 1 1 1 0 IncA protein DUF2628 PF10947.3 EGC29384.1 - 0.26 11.1 4.5 0.46 10.3 3.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2628) DUF4234 PF14018.1 EGC29384.1 - 2.6 7.8 7.6 4.1 7.2 3.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) DUF1049 PF06305.6 EGC29384.1 - 3.2 7.3 6.9 1.2 8.6 0.0 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1049) Erf4 PF10256.4 EGC29385.1 - 4.2e-08 33.0 2.8 2.5e-06 27.3 0.8 2.5 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF898 PF05987.8 EGC29385.1 - 0.11 11.4 3.1 0.15 10.9 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF2207 PF09972.4 EGC29385.1 - 0.34 9.4 6.2 0.48 8.9 4.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) PA14 PF07691.7 EGC29386.1 - 1.5e-15 57.1 0.1 2.5e-15 56.3 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC29386.1 - 0.0017 18.1 7.5 0.0017 18.1 5.2 32.8 31 5 2 33 33 33 10 Dictyostelium (slime mold) repeat Sel1 PF08238.7 EGC29387.1 - 1.1e-08 35.4 0.0 0.04 14.5 0.0 4.8 5 0 0 5 5 5 2 Sel1 repeat TPR_2 PF07719.12 EGC29387.1 - 3.1e-06 26.6 5.3 0.015 15.1 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC29387.1 - 0.00012 21.6 8.5 0.051 13.2 0.0 5.2 5 1 0 5 5 5 2 TPR repeat TPR_12 PF13424.1 EGC29387.1 - 0.0044 16.9 6.2 0.12 12.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29387.1 - 0.018 14.8 0.0 0.018 14.8 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC29387.1 - 0.064 12.8 14.0 0.47 10.1 0.0 5.8 6 0 0 6 6 6 0 Tetratricopeptide repeat DUF2203 PF09969.4 EGC29387.1 - 0.45 10.7 7.7 1 9.6 0.5 3.3 3 1 1 4 4 4 0 Uncharacterized conserved protein (DUF2203) GATA PF00320.22 EGC29389.1 - 5.7e-16 57.5 6.1 1.1e-15 56.6 4.2 1.5 1 0 0 1 1 1 1 GATA zinc finger adh_short PF00106.20 EGC29391.1 - 5.9e-28 97.8 0.2 7.9e-28 97.4 0.1 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29391.1 - 3.3e-15 56.2 0.3 7e-15 55.1 0.2 1.5 1 1 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC29391.1 - 4.7e-10 39.6 0.0 5.7e-10 39.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase 3Beta_HSD PF01073.14 EGC29391.1 - 0.00065 18.4 0.3 0.0022 16.7 0.2 1.7 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Methyltransf_31 PF13847.1 EGC29391.1 - 0.0054 16.3 0.1 0.0075 15.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGC29391.1 - 0.0085 15.6 0.1 0.015 14.8 0.1 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CD52 PF15116.1 EGC29392.1 - 0.077 12.8 1.8 0.14 11.9 1.3 1.4 1 0 0 1 1 1 0 CAMPATH-1 antigen Presenilin PF01080.12 EGC29392.1 - 0.1 11.4 4.5 0.11 11.3 3.1 1.0 1 0 0 1 1 1 0 Presenilin zf-DHHC PF01529.15 EGC29392.1 - 2.5 7.4 4.9 2.6 7.3 3.4 1.0 1 0 0 1 1 1 0 DHHC palmitoyltransferase PRP1_N PF06424.7 EGC29393.1 - 7e-39 133.2 6.7 7e-39 133.2 4.7 2.5 2 0 0 2 2 2 1 PRP1 splicing factor, N-terminal TPR_14 PF13428.1 EGC29393.1 - 6.3e-32 107.1 8.0 0.029 15.0 0.1 13.6 4 4 11 15 15 15 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGC29393.1 - 1.6e-25 89.2 3.2 2.5e-05 24.5 0.0 8.3 6 1 1 7 7 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGC29393.1 - 5.4e-17 61.9 0.2 0.011 16.3 0.0 7.2 5 2 2 8 8 8 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC29393.1 - 1.6e-14 53.3 9.0 0.033 13.8 0.1 9.4 6 3 4 11 11 11 4 TPR repeat TPR_17 PF13431.1 EGC29393.1 - 4.6e-07 29.5 5.3 0.52 10.6 0.0 8.7 11 1 0 11 11 11 1 Tetratricopeptide repeat Suf PF05843.9 EGC29393.1 - 4.7e-07 29.8 5.1 1.3 8.6 0.0 5.4 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_2 PF07719.12 EGC29393.1 - 2e-06 27.2 9.2 4.6 7.4 0.0 9.7 10 0 0 10 10 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29393.1 - 0.00048 19.7 8.0 57 3.8 0.1 8.5 10 1 1 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC29393.1 - 0.0039 17.5 10.1 14 6.3 0.0 8.2 10 0 0 10 10 10 0 Tetratricopeptide repeat Cutinase PF01083.17 EGC29393.1 - 0.097 12.3 0.0 6.4 6.4 0.0 3.6 4 1 0 4 4 4 0 Cutinase DDE_Tnp_4 PF13359.1 EGC29395.1 - 5.6e-07 29.2 0.5 6.9e-07 28.9 0.3 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC29395.1 - 0.11 12.0 1.1 0.3 10.5 0.8 1.8 1 1 0 1 1 1 0 Transposase DDE domain ER_lumen_recept PF00810.13 EGC29396.1 - 7.4e-54 182.2 10.9 9.4e-54 181.9 7.5 1.1 1 0 0 1 1 1 1 ER lumen protein retaining receptor PQ-loop PF04193.9 EGC29396.1 - 0.013 15.0 12.7 0.029 13.9 0.6 3.4 2 1 2 4 4 4 0 PQ loop repeat COX2_TM PF02790.10 EGC29396.1 - 0.31 11.0 5.3 0.16 11.9 0.5 2.4 1 1 1 2 2 2 0 Cytochrome C oxidase subunit II, transmembrane domain VPS9 PF02204.13 EGC29397.1 - 1.3e-30 105.4 0.1 1.3e-30 105.4 0.1 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain PX PF00787.19 EGC29397.1 - 1.7e-17 63.2 0.2 5.2e-17 61.6 0.1 1.9 1 0 0 1 1 1 1 PX domain Ras PF00071.17 EGC29397.1 - 2.3e-08 33.5 0.0 7.6e-08 31.8 0.0 1.9 1 0 0 1 1 1 1 Ras family F-box-like PF12937.2 EGC29398.1 - 0.21 11.3 1.2 0.64 9.7 0.1 2.4 2 1 0 2 2 2 0 F-box-like Pkinase PF00069.20 EGC29399.1 - 1.6e-46 158.5 4.3 6e-46 156.7 0.1 2.9 2 1 0 2 2 2 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGC29399.1 - 6.4e-31 106.8 0.3 6.4e-31 106.8 0.2 2.5 2 0 0 2 2 2 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGC29399.1 - 2.6e-27 95.5 1.7 3.7e-27 95.0 0.0 1.9 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC29399.1 - 6.2e-07 28.6 0.0 1.2e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like PQQ_2 PF13360.1 EGC29399.1 - 1.4e-05 24.6 0.1 0.017 14.6 0.0 2.8 2 1 1 3 3 3 2 PQQ-like domain PQQ PF01011.16 EGC29399.1 - 0.00044 19.6 0.1 0.88 9.2 0.0 3.5 3 0 0 3 3 3 1 PQQ enzyme repeat DUF3899 PF13038.1 EGC29399.1 - 0.0023 18.0 0.4 0.0023 18.0 0.3 3.0 2 1 1 3 3 3 1 Domain of unknown function (DUF3899) SID-1_RNA_chan PF13965.1 EGC29399.1 - 0.05 11.7 10.2 0.1 10.7 7.1 1.4 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Oxidored_q3 PF00499.15 EGC29399.1 - 0.087 12.5 5.5 3.3 7.4 0.8 2.9 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 APH PF01636.18 EGC29399.1 - 0.11 12.1 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 Phosphotransferase enzyme family Neur_chan_memb PF02932.11 EGC29399.1 - 0.15 11.9 5.7 0.35 10.7 3.9 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Shisa PF13908.1 EGC29399.1 - 0.17 12.0 0.2 0.31 11.1 0.1 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator TMEM51 PF15345.1 EGC29399.1 - 0.95 9.1 10.3 0.66 9.6 4.7 2.1 2 0 0 2 2 2 0 Transmembrane protein 51 Bap31 PF05529.7 EGC29399.1 - 1.8 7.9 17.9 5.1 6.4 10.6 2.3 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like Tim44 PF04280.10 EGC29400.1 - 0.021 14.8 0.4 0.021 14.8 0.3 2.2 2 1 0 2 2 2 0 Tim44-like domain DUF936 PF06075.7 EGC29400.1 - 0.19 10.5 10.8 0.31 9.9 7.5 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) SprA-related PF12118.3 EGC29400.1 - 2.2 7.5 14.8 3.1 7.0 10.3 1.2 1 0 0 1 1 1 0 SprA-related family DUF1510 PF07423.6 EGC29400.1 - 6 6.1 26.5 10 5.3 18.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Peptidase_C37 PF05416.7 EGC29400.1 - 7.3 4.7 15.1 12 4.0 10.5 1.3 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CAML PF14963.1 EGC29400.1 - 9.4 5.5 10.6 15 4.8 7.3 1.3 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF1632 PF07857.7 EGC29401.1 - 6.6e-40 136.9 11.6 1.4e-39 135.9 5.0 2.7 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 EGC29401.1 - 9.5e-09 34.7 5.3 9.5e-09 34.7 3.7 3.1 2 2 1 3 3 3 1 Sugar transport protein FA_desaturase PF00487.19 EGC29401.1 - 0.15 11.4 2.7 2.3 7.5 0.1 2.7 2 1 0 2 2 2 0 Fatty acid desaturase Sec20 PF03908.8 EGC29402.1 - 7.7e-17 60.7 4.0 7.7e-17 60.7 2.8 3.0 2 1 2 4 4 4 1 Sec20 GAPT PF11770.3 EGC29402.1 - 0.024 14.3 5.3 0.19 11.3 0.5 2.3 1 1 0 2 2 2 0 GRB2-binding adapter (GAPT) AAA_33 PF13671.1 EGC29403.1 - 3.8e-07 30.0 0.0 2.9e-06 27.2 0.0 2.3 2 0 0 2 2 2 1 AAA domain SWIM PF04434.12 EGC29403.1 - 8.1e-05 22.0 0.4 0.0002 20.7 0.3 1.7 1 0 0 1 1 1 1 SWIM zinc finger Fe_hyd_SSU PF02256.12 EGC29403.1 - 0.0023 17.9 0.0 0.0079 16.1 0.0 2.0 1 0 0 1 1 1 1 Iron hydrogenase small subunit FliC PF12445.3 EGC29403.1 - 0.073 13.1 1.4 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 Flagellin protein Ank_2 PF12796.2 EGC29404.1 - 0.016 15.5 0.0 0.26 11.6 0.0 2.7 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) AIF_C PF14721.1 EGC29407.1 - 1.4 9.1 7.7 13 6.0 4.4 2.3 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PHA-1 PF06542.6 EGC29407.1 - 7.6 5.1 14.1 5.6 5.5 2.7 2.8 2 1 1 3 3 3 0 Regulator protein PHA-1 DUF1900 PF08954.6 EGC29408.1 - 3.2e-13 49.3 0.0 3.7e-13 49.1 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) SMRP1 PF15181.1 EGC29408.1 - 0.0063 15.9 0.0 0.0064 15.9 0.0 1.1 1 0 0 1 1 1 1 Spermatid-specific manchette-related protein 1 DUF4448 PF14610.1 EGC29408.1 - 0.067 12.6 0.1 0.071 12.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) PLDc_N PF13396.1 EGC29409.1 - 2 8.1 5.1 3.1 7.5 3.5 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal DUF3371 PF11851.3 EGC29409.1 - 8.8 7.0 19.5 15 6.2 13.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) MMR1 PF08505.5 EGC29409.1 - 8.9 6.2 16.3 12 5.8 11.3 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein DDE_Tnp_1_2 PF13586.1 EGC29411.1 - 0.62 10.2 3.9 26 5.1 0.1 3.6 3 0 0 3 3 3 0 Transposase DDE domain AAT PF03417.11 EGC29412.1 - 0.056 12.8 0.0 0.059 12.8 0.0 1.0 1 0 0 1 1 1 0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase Ion_trans PF00520.26 EGC29414.1 - 0.0031 16.8 0.1 0.0034 16.6 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein AAA_23 PF13476.1 EGC29414.1 - 0.081 13.2 13.8 0.13 12.5 9.5 1.3 1 0 0 1 1 1 0 AAA domain PLDc_N PF13396.1 EGC29414.1 - 2.5 7.8 5.2 3.6 7.3 3.6 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal AIF_C PF14721.1 EGC29414.1 - 3.2 7.9 7.9 13 6.0 4.6 2.3 2 1 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Nramp PF01566.13 EGC29415.1 - 2.6e-123 411.3 13.8 2.6e-123 411.3 9.6 1.6 2 0 0 2 2 2 1 Natural resistance-associated macrophage protein FA_hydroxylase PF04116.8 EGC29416.1 - 1.5e-19 70.4 15.8 1.5e-19 70.4 10.9 3.5 3 1 0 3 3 3 1 Fatty acid hydroxylase superfamily FlaF PF07309.6 EGC29416.1 - 0.13 12.1 0.1 20 5.0 0.0 2.2 2 0 0 2 2 2 0 Flagellar protein FlaF DUF3792 PF12670.2 EGC29418.1 - 0.0096 15.7 2.6 0.016 15.0 1.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3792) Peptidase_M66 PF10462.4 EGC29419.1 - 6.9e-90 301.0 2.5 9.7e-90 300.5 1.7 1.2 1 0 0 1 1 1 1 Peptidase M66 Metallopep PF12044.3 EGC29419.1 - 0.019 13.4 0.0 0.029 12.8 0.0 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_2 PF13574.1 EGC29419.1 - 0.029 14.4 0.1 0.076 13.0 0.0 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Reprolysin_3 PF13582.1 EGC29419.1 - 0.097 13.1 0.1 0.26 11.8 0.0 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Epiglycanin_C PF14654.1 EGC29420.1 - 0.048 13.6 0.1 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 Mucin, catalytic, TM and cytoplasmic tail region OSTbeta PF15048.1 EGC29420.1 - 0.072 13.1 0.0 0.084 12.9 0.0 1.3 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Shisa PF13908.1 EGC29420.1 - 0.41 10.8 4.0 0.7 10.0 2.8 1.3 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator ATP-synt_8 PF00895.15 EGC29420.1 - 0.99 9.6 6.1 9.9 6.4 4.2 2.5 1 1 0 1 1 1 0 ATP synthase protein 8 Sigma_reg_N PF13800.1 EGC29420.1 - 2.7 8.0 7.3 1.7 8.7 1.9 2.3 1 1 1 2 2 2 0 Sigma factor regulator N-terminal NAD_binding_8 PF13450.1 EGC29421.1 - 0.00012 22.0 0.0 0.00062 19.7 0.0 2.0 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGC29421.1 - 0.00039 19.0 0.0 0.00067 18.2 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_binding_2 PF00890.19 EGC29421.1 - 0.00079 18.3 0.0 0.0011 17.8 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGC29421.1 - 0.0086 15.0 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGC29421.1 - 0.018 14.9 0.1 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGC29421.1 - 0.064 12.1 0.2 0.2 10.4 0.0 1.8 2 0 0 2 2 2 0 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGC29421.1 - 0.088 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein SynMuv_product PF06047.6 EGC29421.1 - 0.11 12.2 0.1 0.27 10.9 0.1 1.7 1 0 0 1 1 1 0 Ras-induced vulval development antagonist TSC22 PF01166.13 EGC29421.1 - 0.31 11.0 6.4 1.6 8.7 0.1 3.4 3 0 0 3 3 3 0 TSC-22/dip/bun family ETRAMP PF09716.5 EGC29422.1 - 0.32 10.9 2.0 0.6 10.1 1.3 1.7 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DASH_Dad4 PF08650.5 EGC29424.1 - 0.035 14.0 0.1 0.097 12.5 0.0 1.7 1 0 0 1 1 1 0 DASH complex subunit Dad4 SRP54 PF00448.17 EGC29428.1 - 4.5e-54 182.8 0.6 2.4e-53 180.5 0.4 2.1 1 1 0 1 1 1 1 SRP54-type protein, GTPase domain SRP-alpha_N PF04086.8 EGC29428.1 - 3.3e-29 102.1 38.0 2.7e-17 63.0 0.2 2.1 1 1 1 2 2 2 2 Signal recognition particle, alpha subunit, N-terminal ArgK PF03308.11 EGC29428.1 - 4.5e-06 25.6 0.0 1.1e-05 24.4 0.0 1.6 1 0 0 1 1 1 1 ArgK protein AAA_22 PF13401.1 EGC29428.1 - 2.5e-05 24.3 0.1 9e-05 22.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain SRP54_N PF02881.14 EGC29428.1 - 7.7e-05 22.7 0.0 7.7e-05 22.7 0.0 3.4 3 0 0 3 3 2 1 SRP54-type protein, helical bundle domain MobB PF03205.9 EGC29428.1 - 8.6e-05 22.2 0.2 0.03 14.0 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGC29428.1 - 0.00018 20.9 0.8 0.00018 20.9 0.5 2.2 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain cobW PF02492.14 EGC29428.1 - 0.00045 19.7 1.7 0.0046 16.4 1.2 2.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain AAA_30 PF13604.1 EGC29428.1 - 0.00064 19.3 0.1 0.0023 17.5 0.0 1.8 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGC29428.1 - 0.0018 18.0 0.1 1.5 8.5 0.0 2.6 1 1 0 2 2 2 2 NTPase AAA_10 PF12846.2 EGC29428.1 - 0.009 15.4 0.1 0.023 14.1 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain ETF PF01012.16 EGC29428.1 - 0.017 14.8 0.1 0.041 13.6 0.1 1.6 1 0 0 1 1 1 0 Electron transfer flavoprotein domain VirC1 PF07015.6 EGC29428.1 - 0.044 12.8 0.1 0.079 12.0 0.1 1.4 1 0 0 1 1 1 0 VirC1 protein AAA_16 PF13191.1 EGC29428.1 - 0.056 13.4 0.0 0.14 12.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain SPOUT_MTase PF02590.12 EGC29428.1 - 0.31 10.7 0.0 0.31 10.7 0.0 2.4 2 0 0 2 2 2 0 Predicted SPOUT methyltransferase La PF05383.12 EGC29429.1 - 4.5e-17 61.5 0.1 1.5e-16 59.9 0.1 1.9 1 0 0 1 1 1 1 La domain DUF1493 PF07377.7 EGC29430.1 - 0.19 11.8 2.0 0.25 11.4 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1493) DHC_N1 PF08385.7 EGC29433.1 - 0.048 12.0 0.5 0.047 12.0 0.3 1.1 1 0 0 1 1 1 0 Dynein heavy chain, N-terminal region 1 DUF603 PF04645.7 EGC29433.1 - 0.053 13.4 0.9 0.055 13.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function, DUF603 DUF2959 PF11172.3 EGC29433.1 - 0.064 13.0 0.8 0.064 13.0 0.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) SYF2 PF08231.7 EGC29433.1 - 0.13 12.3 3.3 0.15 12.1 2.3 1.0 1 0 0 1 1 1 0 SYF2 splicing factor PaaSYMP PF14738.1 EGC29433.1 - 0.19 11.4 1.8 0.19 11.4 1.3 1.0 1 0 0 1 1 1 0 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 SAP PF02037.22 EGC29434.1 - 4.3e-07 29.2 0.2 1.5e-06 27.5 0.0 2.2 2 0 0 2 2 2 1 SAP domain SNF2_N PF00176.18 EGC29434.1 - 0.16 10.7 3.8 0.44 9.3 2.7 1.7 1 0 0 1 1 1 0 SNF2 family N-terminal domain ACCA PF03255.9 EGC29434.1 - 8.3 5.9 10.5 0.71 9.4 2.5 2.8 3 0 0 3 3 3 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit RhoGAP PF00620.22 EGC29435.1 - 2.4e-34 118.1 1.2 2.4e-34 118.1 0.8 2.8 2 0 0 2 2 2 1 RhoGAP domain DDOST_48kD PF03345.9 EGC29437.1 - 9.5e-124 413.1 1.0 1.1e-123 412.8 0.7 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase 48 kDa subunit beta DUF4350 PF14258.1 EGC29437.1 - 0.0039 17.3 0.1 0.29 11.3 0.0 2.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4350) RhoGAP PF00620.22 EGC29438.1 - 0.0082 15.7 3.9 0.064 12.8 0.4 2.7 2 0 0 2 2 2 2 RhoGAP domain Pkinase PF00069.20 EGC29439.1 - 5.6e-78 261.6 0.0 7.5e-78 261.2 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29439.1 - 1.2e-41 142.5 0.0 1.8e-41 141.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGC29439.1 - 2.8e-07 29.8 0.3 5.9e-07 28.8 0.2 1.6 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EGC29439.1 - 3.3e-06 26.2 0.0 5.6e-06 25.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGC29439.1 - 0.00016 21.0 1.1 0.00027 20.3 0.7 1.3 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC29439.1 - 0.017 14.8 0.0 0.95 9.1 0.1 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family NAP PF00956.13 EGC29440.1 - 8.8e-25 87.2 11.9 8.8e-25 87.2 8.3 2.6 1 1 1 2 2 2 1 Nucleosome assembly protein (NAP) PAT1 PF09770.4 EGC29440.1 - 0.72 8.0 23.2 0.81 7.8 16.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EGC29440.1 - 1.2 8.4 19.9 1.6 8.0 13.8 1.3 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 EGC29440.1 - 2.1 8.1 8.4 2.8 7.7 5.8 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SAGA-Tad1 PF12767.2 EGC29440.1 - 9.2 5.8 17.5 12 5.4 12.1 1.1 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit Ran_BP1 PF00638.13 EGC29441.1 - 6.8e-18 64.8 3.1 1.1e-17 64.2 1.7 1.8 1 1 0 1 1 1 1 RanBP1 domain Dicty_CTDC PF00526.13 EGC29442.1 - 2.2e-25 87.9 96.8 2.8e-08 33.4 8.7 8.0 8 0 0 8 8 8 7 Dictyostelium (slime mold) repeat RNase_P_Rpp14 PF01900.14 EGC29443.1 - 1.3e-08 34.6 0.0 1.8e-08 34.2 0.0 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family PPR_2 PF13041.1 EGC29444.1 - 1.7e-15 56.7 10.3 1.3e-07 31.4 0.3 5.6 3 1 2 5 5 5 4 PPR repeat family PPR_3 PF13812.1 EGC29444.1 - 9.2e-15 53.6 0.0 0.013 15.7 0.0 6.2 7 0 0 7 7 7 3 Pentatricopeptide repeat domain PPR PF01535.15 EGC29444.1 - 1.5e-13 49.7 6.5 0.00014 21.6 0.1 6.1 7 0 0 7 7 7 3 PPR repeat PPR_1 PF12854.2 EGC29444.1 - 7.2e-08 31.7 5.6 4.8e-07 29.1 0.2 3.6 4 0 0 4 4 4 1 PPR repeat TPR_19 PF14559.1 EGC29444.1 - 0.012 15.9 1.4 12 6.2 0.2 3.7 3 1 0 3 3 3 0 Tetratricopeptide repeat ATP13 PF12921.2 EGC29444.1 - 0.061 12.6 3.9 1.2 8.5 0.1 3.4 2 2 2 4 4 4 0 Mitochondrial ATPase expression Methyltransf_2 PF00891.13 EGC29444.1 - 0.095 11.8 0.5 0.27 10.3 0.2 1.9 1 1 1 2 2 2 0 O-methyltransferase Cyclin_N PF00134.18 EGC29445.1 - 1.1e-27 96.0 0.2 7.7e-27 93.3 0.0 2.6 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC29445.1 - 7.9e-22 77.3 4.7 2.2e-21 75.9 0.5 3.4 1 1 2 4 4 4 1 Cyclin, C-terminal domain CBF_beta PF02312.12 EGC29446.1 - 0.0035 16.9 0.0 0.0038 16.8 0.0 1.1 1 0 0 1 1 1 1 Core binding factor beta subunit Anoctamin PF04547.7 EGC29449.1 - 3.8e-14 52.2 24.5 3.8e-14 52.2 17.0 2.4 2 1 0 2 2 2 1 Calcium-activated chloride channel DUF221 PF02714.10 EGC29449.1 - 1.4e-10 40.5 16.3 1.4e-10 40.5 11.3 3.0 1 1 1 2 2 2 1 Domain of unknown function DUF221 TMC PF07810.8 EGC29449.1 - 6.2e-07 29.8 0.0 6.2e-07 29.8 0.0 3.0 3 0 0 3 3 3 1 TMC domain Gemini_AL2 PF01440.11 EGC29449.1 - 3.4 7.7 10.5 5.7 7.0 7.3 1.3 1 0 0 1 1 1 0 Geminivirus AL2 protein FNIP PF05725.7 EGC29450.1 - 2.1e-18 65.9 72.1 4.2e-05 23.3 1.2 11.8 8 3 3 11 11 11 8 FNIP Repeat ApoL PF05461.6 EGC29450.1 - 0.0021 17.3 2.3 0.0032 16.7 1.6 1.2 1 0 0 1 1 1 1 Apolipoprotein L IncA PF04156.9 EGC29450.1 - 1.4 8.4 8.7 0.11 12.0 2.5 1.8 2 0 0 2 2 2 0 IncA protein OTU PF02338.14 EGC29451.1 - 1.9e-14 54.2 0.0 1.9e-14 54.2 0.0 2.2 2 1 0 2 2 2 1 OTU-like cysteine protease IncA PF04156.9 EGC29451.1 - 0.0081 15.7 3.3 0.0081 15.7 2.3 2.2 2 0 0 2 2 2 1 IncA protein DUF1980 PF09323.5 EGC29451.1 - 0.28 10.9 7.2 0.17 11.6 2.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Tetraspannin PF00335.15 EGC29451.1 - 0.31 10.2 4.9 0.5 9.6 3.4 1.3 1 0 0 1 1 1 0 Tetraspanin family TFIIA PF03153.8 EGC29451.1 - 0.83 9.4 26.2 1.2 8.9 18.2 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SSDP PF04503.8 EGC29451.1 - 1.4 8.6 16.0 2 8.1 11.1 1.1 1 0 0 1 1 1 0 Single-stranded DNA binding protein, SSDP PAT1 PF09770.4 EGC29451.1 - 1.4 7.0 40.8 1.9 6.6 28.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAT1 PF06391.8 EGC29451.1 - 1.5 8.3 17.1 0.48 9.9 9.7 1.7 1 1 0 1 1 1 0 CDK-activating kinase assembly factor MAT1 TMEM51 PF15345.1 EGC29451.1 - 6.3 6.4 16.4 14 5.2 11.3 1.6 1 1 0 1 1 1 0 Transmembrane protein 51 DUF2204 PF09970.4 EGC29452.1 - 0.19 11.2 5.7 0.32 10.4 4.0 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) CPW_WPC PF09717.5 EGC29454.1 - 0.016 15.8 18.0 20 5.9 0.6 5.1 1 1 2 3 3 3 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Phage_gp49_66 PF13876.1 EGC29454.1 - 2.1 8.4 10.2 84 3.3 0.4 5.3 3 3 0 4 4 4 0 Phage protein (N4 Gp49/phage Sf6 gene 66) family Gamma-thionin PF00304.15 EGC29454.1 - 9.9 6.2 10.9 70 3.5 1.0 3.8 1 1 4 5 5 5 0 Gamma-thionin family DUF3595 PF12166.3 EGC29456.1 - 2.5 6.8 15.5 2.9 6.6 10.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Alpha_E1_glycop PF01589.11 EGC29457.1 - 0.14 10.4 0.0 0.17 10.1 0.0 1.1 1 0 0 1 1 1 0 Alphavirus E1 glycoprotein IBR PF01485.16 EGC29458.1 - 3.1e-16 58.9 42.4 3.2e-09 36.5 10.5 2.6 2 0 0 2 2 2 2 IBR domain RNA_pol_Rpb1_5 PF04998.12 EGC29458.1 - 0.8 8.9 4.2 1.1 8.4 2.9 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 PQ-loop PF04193.9 EGC29459.1 - 4.4e-22 77.3 12.9 4.3e-14 51.7 3.4 2.7 2 0 0 2 2 2 2 PQ loop repeat MtN3_slv PF03083.11 EGC29459.1 - 0.012 15.5 1.8 0.012 15.5 1.3 2.5 2 1 0 2 2 2 0 Sugar efflux transporter for intercellular exchange SAP PF02037.22 EGC29460.1 - 0.00014 21.2 0.2 0.00089 18.6 0.0 2.1 2 0 0 2 2 2 1 SAP domain A2M_N PF01835.14 EGC29461.1 - 9.7e-10 38.5 0.3 1.3e-06 28.5 0.0 4.3 4 0 0 4 4 4 1 MG2 domain A2M_N_2 PF07703.9 EGC29461.1 - 5.6e-05 22.9 0.0 0.00026 20.7 0.0 2.3 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region A2M PF00207.17 EGC29461.1 - 6.6e-05 22.4 0.0 0.00031 20.2 0.0 2.2 1 0 0 1 1 1 1 Alpha-2-macroglobulin family MG1 PF11974.3 EGC29461.1 - 0.00013 22.4 0.1 0.00053 20.4 0.0 2.1 1 0 0 1 1 1 1 Alpha-2-macroglobulin MG1 domain CH PF00307.26 EGC29462.1 - 1.2e-14 54.2 0.3 1.3e-06 28.3 0.0 2.6 2 0 0 2 2 2 2 Calponin homology (CH) domain RA PF00788.18 EGC29462.1 - 5.3e-13 49.2 5.5 1.4e-06 28.7 0.0 3.5 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain dsrm PF00035.20 EGC29463.1 - 2.6e-12 47.1 0.3 1e-11 45.2 0.1 2.2 2 0 0 2 2 2 1 Double-stranded RNA binding motif Proteasom_PSMB PF10508.4 EGC29464.1 - 3.2e-20 71.8 15.5 4.6e-19 68.0 3.9 2.0 2 0 0 2 2 2 2 Proteasome non-ATPase 26S subunit Rsbr_N PF08678.5 EGC29464.1 - 0.013 15.4 4.4 0.89 9.4 0.1 3.7 3 1 0 3 3 3 0 Rsbr N terminal BCAS3 PF12490.3 EGC29465.1 - 9.6e-18 64.3 0.4 9.6e-18 64.3 0.3 3.1 2 1 1 3 3 3 1 Breast carcinoma amplified sequence 3 Oxysterol_BP PF01237.13 EGC29466.1 - 2e-81 273.2 2.2 1.5e-80 270.3 1.5 1.9 1 1 0 1 1 1 1 Oxysterol-binding protein FAD_oxidored PF12831.2 EGC29466.1 - 0.11 11.4 0.1 0.17 10.9 0.1 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase JAB PF01398.16 EGC29467.1 - 1.3e-36 124.7 0.3 2.7e-36 123.7 0.0 1.6 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease MitMem_reg PF13012.1 EGC29467.1 - 1.3e-27 96.1 4.2 2.6e-27 95.1 2.6 1.8 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function Prok-JAB PF14464.1 EGC29467.1 - 2.9e-09 36.4 0.0 4.5e-09 35.8 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF2989 PF11207.3 EGC29467.1 - 0.01 15.3 0.2 0.017 14.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2989) Sec7 PF01369.15 EGC29468.1 - 5e-60 202.4 0.0 5e-60 202.4 0.0 2.2 3 0 0 3 3 3 1 Sec7 domain PH PF00169.24 EGC29468.1 - 6.7e-06 26.2 7.7 0.00026 21.1 0.1 3.4 2 1 0 2 2 2 2 PH domain PH_11 PF15413.1 EGC29468.1 - 0.0009 19.4 0.2 0.0009 19.4 0.2 3.6 3 1 0 3 3 3 1 Pleckstrin homology domain ApbA_C PF08546.6 EGC29469.1 - 0.043 13.8 0.0 0.059 13.3 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Sulfotransfer_1 PF00685.22 EGC29470.1 - 3.8e-17 62.4 2.0 3.8e-17 62.4 1.4 3.0 2 1 0 2 2 2 1 Sulfotransferase domain Glycos_transf_1 PF00534.15 EGC29470.1 - 2.1e-14 53.3 0.1 2.1e-14 53.3 0.1 2.4 3 0 0 3 3 3 1 Glycosyl transferases group 1 Sulfotransfer_3 PF13469.1 EGC29470.1 - 1.5e-07 32.4 0.0 2.7e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Sulfotransferase family Glyco_transf_5 PF08323.6 EGC29470.1 - 0.00025 20.6 0.1 0.0016 17.9 0.0 2.3 2 0 0 2 2 2 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EGC29470.1 - 0.097 12.8 0.0 0.2 11.8 0.0 1.5 1 1 0 1 1 1 0 Glycosyl transferase 4-like domain FNIP PF05725.7 EGC29471.1 - 2.8e-70 232.0 43.5 3.7e-15 55.5 3.6 7.8 5 2 0 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC29471.1 - 0.013 15.3 18.8 1.3 9.0 0.1 8.0 4 2 5 9 9 9 0 Protein of unknown function (DUF1769) tRNA-synt_2d PF01409.15 EGC29472.1 - 2.3e-50 171.1 4.4 2e-30 105.7 0.1 2.2 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) FDX-ACB PF03147.9 EGC29472.1 - 3.4e-23 81.6 2.2 6.8e-23 80.6 0.1 2.5 2 0 0 2 2 2 1 Ferredoxin-fold anticodon binding domain Pro_isomerase PF00160.16 EGC29473.1 - 1.2e-45 155.4 0.4 1.4e-45 155.3 0.3 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FNIP PF05725.7 EGC29474.1 - 1.6e-14 53.5 22.4 0.00037 20.3 0.8 4.4 3 1 2 5 5 5 5 FNIP Repeat Glyco_hydro_114 PF03537.8 EGC29474.1 - 0.06 13.1 0.0 1.1 9.0 0.0 2.2 1 1 1 2 2 2 0 Glycoside-hydrolase family GH114 SAP PF02037.22 EGC29475.1 - 0.00063 19.1 0.1 0.0021 17.5 0.1 1.9 2 0 0 2 2 2 1 SAP domain AAA_14 PF13173.1 EGC29476.1 - 0.067 13.0 0.2 0.56 10.1 0.0 2.3 1 1 1 2 2 2 0 AAA domain DUF3320 PF11784.3 EGC29476.1 - 0.075 12.5 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3320) RecU PF03838.9 EGC29478.1 - 0.012 15.1 3.7 0.016 14.6 2.6 1.1 1 0 0 1 1 1 0 Recombination protein U Chordopox_A13L PF05961.6 EGC29478.1 - 0.013 15.4 0.6 0.013 15.4 0.4 2.2 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Secretin_N_2 PF07655.8 EGC29478.1 - 0.86 10.0 9.5 0.32 11.4 1.1 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain Glycohydro_20b2 PF14845.1 EGC29478.1 - 3 8.5 6.3 4.9 7.8 4.3 1.4 1 1 0 1 1 1 0 beta-acetyl hexosaminidase like zf-RING_2 PF13639.1 EGC29479.1 - 4.1e-09 36.1 8.9 7.3e-09 35.3 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC29479.1 - 7.6e-09 35.0 7.4 1.7e-08 33.9 5.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29479.1 - 8.1e-07 28.9 9.1 1.5e-06 28.1 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC29479.1 - 1.6e-06 27.6 3.7 2.6e-06 27.0 2.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) PWI PF01480.12 EGC29479.1 - 4.1e-06 26.8 0.4 4.1e-06 26.8 0.3 3.2 3 1 1 4 4 3 1 PWI domain zf-Apc11 PF12861.2 EGC29479.1 - 1.3e-05 24.8 2.1 2.6e-05 23.9 1.5 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGC29479.1 - 3.1e-05 24.0 7.3 8.7e-05 22.5 5.0 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC29479.1 - 0.00022 20.8 7.1 0.00043 19.9 4.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29479.1 - 0.021 14.7 10.2 0.05 13.4 7.0 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC29479.1 - 0.11 12.0 6.7 0.39 10.3 4.8 1.8 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Vps39_2 PF10367.4 EGC29479.1 - 0.19 11.9 0.0 0.19 11.9 0.0 3.9 4 1 1 5 5 5 0 Vacuolar sorting protein 39 domain 2 Rad50_zn_hook PF04423.9 EGC29479.1 - 0.77 9.2 11.6 1.1 8.7 0.1 3.9 3 0 0 3 3 3 0 Rad50 zinc hook motif SNARE PF05739.14 EGC29480.1 - 6.6e-11 41.7 4.1 2.2e-10 40.0 2.9 2.0 1 0 0 1 1 1 1 SNARE domain COesterase PF00135.23 EGC29480.1 - 0.0043 15.8 1.5 0.0053 15.5 1.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family ODV-E18 PF10717.4 EGC29480.1 - 0.034 13.5 1.1 0.15 11.5 0.8 2.1 1 0 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 ABC2_membrane_3 PF12698.2 EGC29480.1 - 0.091 11.7 3.9 0.11 11.5 2.7 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein TMPIT PF07851.8 EGC29480.1 - 0.39 9.7 2.8 0.19 10.7 0.4 1.5 2 0 0 2 2 2 0 TMPIT-like protein DUF843 PF05814.6 EGC29480.1 - 1.4 8.8 6.4 1.8 8.4 0.1 2.8 3 0 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) 2OG-FeII_Oxy_2 PF13532.1 EGC29481.1 - 2.8e-16 59.9 0.0 9.2e-16 58.2 0.0 1.7 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGC29481.1 - 5.9e-06 26.5 0.0 8.7e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TetR_C_8 PF14278.1 EGC29481.1 - 1.3 9.4 3.8 26 5.2 0.1 3.1 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region MEKHLA PF08670.6 EGC29483.1 - 0.083 12.4 0.0 0.14 11.7 0.0 1.4 1 1 1 2 2 2 0 MEKHLA domain DUF3104 PF11302.3 EGC29483.1 - 0.12 11.7 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3104) DUF581 PF04570.9 EGC29483.1 - 0.16 11.3 0.6 0.4 9.9 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF581) BTK PF00779.14 EGC29483.1 - 0.23 11.1 0.2 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 BTK motif FNIP PF05725.7 EGC29486.1 - 2.5e-94 309.0 61.7 2.5e-11 43.3 0.6 12.7 4 3 6 13 13 13 13 FNIP Repeat LRR_5 PF13306.1 EGC29486.1 - 1.2e-07 31.4 2.4 0.017 14.7 0.1 4.0 3 1 0 3 3 3 2 Leucine rich repeats (6 copies) Sel1 PF08238.7 EGC29487.1 - 1.5e-12 47.7 5.1 0.0017 18.9 0.0 4.6 5 0 0 5 5 5 3 Sel1 repeat TPR_11 PF13414.1 EGC29487.1 - 1.9e-05 24.2 4.8 0.84 9.3 0.7 3.2 2 1 1 3 3 3 3 TPR repeat TPR_6 PF13174.1 EGC29487.1 - 0.0071 16.7 2.7 46 4.7 0.0 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC29487.1 - 0.11 12.4 6.2 2.4 8.3 1.1 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TRP PF06011.7 EGC29488.1 - 4.1e-05 22.3 29.1 0.024 13.2 0.1 2.9 1 1 0 2 2 2 2 Transient receptor potential (TRP) ion channel EGF_2 PF07974.8 EGC29488.1 - 0.00016 21.7 58.2 0.029 14.5 6.7 4.3 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.2 EGC29488.1 - 0.00049 19.9 17.1 0.17 11.9 0.7 4.0 3 0 0 3 3 3 2 Human growth factor-like EGF EGF PF00008.22 EGC29488.1 - 1.3 9.0 45.1 0.078 12.9 6.6 4.4 4 0 0 4 4 4 0 EGF-like domain Sgf11 PF08209.6 EGC29490.1 - 0.00013 21.2 0.3 0.00022 20.4 0.2 1.3 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DAGK_cat PF00781.19 EGC29491.1 - 4.7e-22 77.8 0.0 8.6e-22 76.9 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain DUF4140 PF13600.1 EGC29491.1 - 0.099 13.1 0.3 0.2 12.0 0.2 1.5 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Tox-REase-3 PF15647.1 EGC29491.1 - 0.23 11.2 3.2 4.8 7.0 0.4 2.8 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 3 SLIDE PF09111.5 EGC29491.1 - 6.4 6.5 8.8 1.2 8.9 1.0 2.9 3 0 0 3 3 3 0 SLIDE Lyase_aromatic PF00221.14 EGC29492.1 - 1.5e-152 508.3 0.0 1.8e-152 508.1 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase FNIP PF05725.7 EGC29493.1 - 2.3e-83 273.9 74.8 1.8e-13 50.2 0.7 13.5 9 3 6 15 15 15 14 FNIP Repeat UDG PF03167.14 EGC29494.1 - 4e-19 68.5 0.0 4.7e-19 68.3 0.0 1.1 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily Acyl_transf_3 PF01757.17 EGC29495.1 - 4.9e-19 68.3 51.8 4.9e-19 68.3 35.9 1.8 2 0 0 2 2 2 1 Acyltransferase family NAD_binding_2 PF03446.10 EGC29496.1 - 1.3e-55 187.6 0.5 1.7e-55 187.2 0.3 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase NAD_binding_11 PF14833.1 EGC29496.1 - 1.3e-34 118.8 0.0 2.3e-34 118.0 0.0 1.4 1 0 0 1 1 1 1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase F420_oxidored PF03807.12 EGC29496.1 - 1.9e-09 37.8 0.0 5.3e-09 36.4 0.0 1.7 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent 2-Hacid_dh_C PF02826.14 EGC29496.1 - 8.8e-09 34.7 0.0 1.7e-08 33.8 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IlvN PF07991.7 EGC29496.1 - 7.7e-06 25.3 0.0 1.3e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain UDPG_MGDP_dh_N PF03721.9 EGC29496.1 - 3.7e-05 23.1 0.1 0.0011 18.3 0.0 2.3 1 1 1 2 2 2 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGC29496.1 - 0.00022 20.9 0.1 0.00041 20.0 0.0 1.5 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGC29496.1 - 0.0013 18.4 0.2 0.0069 16.1 0.1 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus TrkA_N PF02254.13 EGC29496.1 - 0.0094 15.9 0.0 0.017 15.1 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ApbA PF02558.11 EGC29496.1 - 0.013 14.9 0.0 0.022 14.2 0.0 1.4 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA GFO_IDH_MocA PF01408.17 EGC29496.1 - 0.015 15.8 0.1 0.037 14.5 0.0 1.7 2 0 0 2 2 1 0 Oxidoreductase family, NAD-binding Rossmann fold OCD_Mu_crystall PF02423.10 EGC29496.1 - 0.036 12.8 0.0 0.048 12.4 0.0 1.2 1 0 0 1 1 1 0 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EGC29496.1 - 0.068 13.2 0.0 0.1 12.7 0.0 1.3 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Coiled PF05710.7 EGC29496.1 - 0.14 12.6 5.6 0.14 12.6 2.4 2.2 1 1 1 2 2 2 0 Coiled coil Sec7 PF01369.15 EGC29497.1 - 9.8e-65 217.7 1.4 9.8e-65 217.7 1.0 2.2 2 0 0 2 2 2 1 Sec7 domain PH PF00169.24 EGC29497.1 - 4.8e-18 65.2 0.9 4.8e-18 65.2 0.6 2.9 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC29497.1 - 3e-07 30.6 0.6 3e-07 30.6 0.4 4.1 4 1 0 4 4 4 1 Pleckstrin homology domain DUF2666 PF10869.3 EGC29497.1 - 0.0025 17.8 0.0 0.0025 17.8 0.0 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF2666) WD40 PF00400.27 EGC29498.1 - 1.8e-12 46.5 17.3 7.4e-05 22.4 0.0 6.2 6 1 0 6 6 6 4 WD domain, G-beta repeat Mucin PF01456.12 EGC29498.1 - 0.58 9.9 28.3 1 9.1 19.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein IBR PF01485.16 EGC29499.1 - 3.1e-24 84.6 46.5 2.6e-15 56.0 3.3 4.4 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGC29499.1 - 7.3e-07 28.9 36.4 2.3e-05 24.1 7.6 3.7 3 0 0 3 3 3 3 Ring finger domain zf-RING_5 PF14634.1 EGC29499.1 - 0.00067 19.3 43.2 0.011 15.4 6.6 4.0 3 1 1 4 4 4 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC29499.1 - 0.0013 18.2 10.9 0.0013 18.2 7.5 5.2 3 3 1 5 5 5 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29499.1 - 0.021 14.8 12.9 0.021 14.8 8.9 4.5 3 1 1 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-piccolo PF05715.8 EGC29499.1 - 7 6.7 27.5 0.1 12.5 4.7 3.1 3 0 0 3 3 3 0 Piccolo Zn-finger MIT PF04212.13 EGC29500.1 - 4.1e-28 97.0 10.3 1.2e-15 57.1 1.3 3.0 3 0 0 3 3 3 2 MIT (microtubule interacting and transport) domain TPR_11 PF13414.1 EGC29500.1 - 0.0012 18.4 0.4 1.2 8.7 0.1 2.4 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGC29500.1 - 0.028 14.0 0.5 9.3 6.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat Aida_N PF08910.5 EGC29500.1 - 0.089 13.0 0.3 0.3 11.3 0.0 2.0 2 0 0 2 2 2 0 Aida N-terminus WD40 PF00400.27 EGC29501.1 - 2e-54 179.5 22.8 5.2e-10 38.8 0.2 11.2 11 0 0 11 11 11 10 WD domain, G-beta repeat Nup160 PF11715.3 EGC29501.1 - 0.00084 17.5 2.2 0.027 12.6 0.1 2.8 3 0 0 3 3 3 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EGC29501.1 - 0.0051 14.7 2.6 0.23 9.2 0.1 2.5 3 0 0 3 3 3 2 IKI3 family SdiA-regulated PF06977.6 EGC29501.1 - 0.029 13.3 0.0 0.77 8.6 0.0 2.4 2 0 0 2 2 2 0 SdiA-regulated YmzC PF14157.1 EGC29501.1 - 0.038 13.8 0.5 0.38 10.6 0.0 2.8 3 0 0 3 3 3 0 YmzC-like protein IL12p40_C PF10420.4 EGC29501.1 - 0.063 13.3 5.4 0.49 10.5 0.2 3.5 3 1 0 3 3 3 0 Cytokine interleukin-12p40 C-terminus Secretin_N_2 PF07655.8 EGC29502.1 - 0.025 14.9 18.7 0.037 14.4 13.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Pex14_N PF04695.8 EGC29502.1 - 0.053 13.5 3.8 0.067 13.2 2.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF506 PF04720.7 EGC29502.1 - 0.13 11.8 1.6 0.16 11.5 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Ashwin PF15323.1 EGC29502.1 - 0.96 9.4 6.2 1.1 9.1 4.3 1.1 1 0 0 1 1 1 0 Developmental protein DUF1390 PF07150.6 EGC29502.1 - 2.9 7.1 10.7 3.3 6.9 7.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) NTP_transf_2 PF01909.18 EGC29504.1 - 0.027 14.7 0.4 0.49 10.7 0.0 2.2 2 0 0 2 2 2 0 Nucleotidyltransferase domain Glyco_trans_1_3 PF13528.1 EGC29504.1 - 0.042 13.0 0.0 0.085 12.0 0.0 1.5 2 0 0 2 2 2 0 Glycosyl transferase family 1 RVT_2 PF07727.9 EGC29504.1 - 0.076 11.9 0.0 0.093 11.6 0.0 1.1 1 0 0 1 1 1 0 Reverse transcriptase (RNA-dependent DNA polymerase) SPC25 PF06703.6 EGC29504.1 - 0.15 11.6 0.8 0.2 11.2 0.2 1.5 2 0 0 2 2 2 0 Microsomal signal peptidase 25 kDa subunit (SPC25) SSP160 PF06933.6 EGC29504.1 - 0.18 9.7 8.1 0.22 9.4 5.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGC29504.1 - 0.84 9.3 10.0 1.4 8.6 6.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) E1-E2_ATPase PF00122.15 EGC29505.1 - 9.4e-61 204.7 1.9 1.7e-60 203.9 1.3 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC29505.1 - 2e-42 144.7 3.7 2e-42 144.7 2.5 2.4 2 1 1 3 3 3 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC29505.1 - 3e-30 106.2 0.0 1.8e-29 103.6 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC29505.1 - 3.1e-24 84.7 0.0 6.4e-24 83.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_N PF00690.21 EGC29505.1 - 4.1e-19 67.8 0.0 7.9e-19 66.8 0.0 1.5 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus HAD PF12710.2 EGC29505.1 - 7.6e-13 49.0 0.0 2.2e-12 47.5 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGC29505.1 - 7.2e-07 29.0 1.0 0.00035 20.2 0.3 2.5 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF2269 PF10027.4 EGC29505.1 - 0.014 15.2 0.1 6.2 6.5 0.0 2.5 2 0 0 2 2 2 0 Predicted integral membrane protein (DUF2269) COX7C PF02935.11 EGC29505.1 - 0.067 13.0 0.2 9.2 6.1 0.0 3.1 3 0 0 3 3 3 0 Cytochrome c oxidase subunit VIIc zf-CCHC_3 PF13917.1 EGC29506.1 - 3.8e-07 29.7 0.1 1.2e-06 28.1 0.1 1.9 1 0 0 1 1 1 1 Zinc knuckle EF-hand_7 PF13499.1 EGC29508.1 - 8e-15 54.7 8.9 1.2e-07 31.6 3.2 3.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC29508.1 - 6.6e-13 47.3 6.6 0.01 15.6 0.0 4.2 3 1 1 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 EGC29508.1 - 1.8e-12 45.5 10.6 0.0048 16.1 0.3 4.4 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EGC29508.1 - 1.8e-05 24.2 6.0 0.19 11.3 0.6 3.6 3 1 1 4 4 4 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC29508.1 - 6.4e-05 22.9 3.7 0.0033 17.4 0.3 2.7 1 1 1 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_like PF09279.6 EGC29508.1 - 0.002 18.1 0.7 1.4 9.0 0.0 2.5 2 1 0 2 2 2 2 Phosphoinositide-specific phospholipase C, efhand-like DUF2497 PF10691.4 EGC29508.1 - 0.006 16.5 0.1 0.29 11.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2497) Sec34 PF04136.10 EGC29508.1 - 0.015 14.9 1.8 1.9 8.1 0.1 2.2 1 1 1 2 2 2 0 Sec34-like family PrkA PF06798.7 EGC29508.1 - 0.021 14.1 0.9 0.03 13.5 0.5 1.3 1 1 0 1 1 1 0 PrkA serine protein kinase C-terminal domain E2F_TDP PF02319.15 EGC29508.1 - 0.028 13.9 1.1 1.5 8.4 0.1 2.5 2 1 0 2 2 2 0 E2F/DP family winged-helix DNA-binding domain EF-hand_5 PF13202.1 EGC29508.1 - 0.032 13.5 7.1 2.8 7.4 0.1 4.3 4 0 0 4 4 4 0 EF hand XkdN PF08890.6 EGC29508.1 - 0.034 13.8 1.2 0.079 12.6 0.4 1.8 1 1 1 2 2 2 0 Phage XkdN-like protein PRP38 PF03371.10 EGC29508.1 - 0.038 13.6 1.9 3.1 7.3 0.0 2.2 2 0 0 2 2 2 0 PRP38 family Ubiq_cyt_C_chap PF03981.7 EGC29508.1 - 0.14 12.0 0.1 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Ubiquinol-cytochrome C chaperone Orthopox_B11R PF07033.6 EGC29508.1 - 0.21 11.0 2.7 8.3 5.9 0.0 3.1 2 1 0 3 3 3 0 Orthopoxvirus B11R protein DUF1103 PF06513.6 EGC29508.1 - 0.39 10.0 6.5 0.57 9.5 4.5 1.2 1 0 0 1 1 1 0 Repeat of unknown function (DUF1103) ParB PF08775.5 EGC29508.1 - 0.83 9.9 4.9 3.2 8.0 0.1 2.2 1 1 1 2 2 2 0 ParB family Formyl_trans_N PF00551.14 EGC29509.1 - 1e-23 83.8 0.0 1.5e-23 83.2 0.0 1.3 1 0 0 1 1 1 1 Formyl transferase Formyl_trans_C PF02911.13 EGC29509.1 - 0.031 14.3 0.1 0.49 10.5 0.1 2.5 1 1 0 1 1 1 0 Formyl transferase, C-terminal domain GYR PF02756.9 EGC29509.1 - 0.38 10.5 2.0 0.81 9.5 1.4 1.5 1 0 0 1 1 1 0 GYR motif PH PF00169.24 EGC29510.1 - 8.7e-06 25.8 6.7 8.7e-06 25.8 4.6 2.9 2 2 0 2 2 2 1 PH domain Methyltransf_23 PF13489.1 EGC29511.1 - 9.4e-21 74.2 0.0 1.3e-20 73.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29511.1 - 5.7e-18 64.9 0.1 9.3e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC29511.1 - 2.5e-15 56.7 0.0 4.7e-15 55.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29511.1 - 6.2e-12 46.0 0.0 9.9e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29511.1 - 8.7e-11 42.1 0.1 8.7e-11 42.1 0.1 2.1 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGC29511.1 - 2.3e-08 33.5 0.1 3.7e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGC29511.1 - 1.3e-07 31.0 0.0 1.7e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_9 PF08003.6 EGC29511.1 - 3.7e-07 29.1 0.0 5e-07 28.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGC29511.1 - 3.7e-07 30.4 0.0 6.3e-07 29.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC29511.1 - 2.3e-06 26.9 0.0 3.1e-06 26.4 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGC29511.1 - 0.00014 21.3 0.3 0.00047 19.5 0.2 1.8 1 1 0 1 1 1 1 Methyltransferase small domain NodS PF05401.6 EGC29511.1 - 0.0003 20.2 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 Nodulation protein S (NodS) GidB PF02527.10 EGC29511.1 - 0.00038 19.6 0.0 0.35 9.9 0.0 2.3 2 0 0 2 2 2 2 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EGC29511.1 - 0.00042 20.3 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC29511.1 - 0.0021 17.1 0.0 1.5 7.8 0.0 2.2 2 0 0 2 2 2 2 Putative methyltransferase Methyltransf_32 PF13679.1 EGC29511.1 - 0.0034 17.0 0.1 0.008 15.8 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Pox_MCEL PF03291.11 EGC29511.1 - 0.0046 15.8 0.6 0.016 14.1 0.4 1.7 1 1 0 1 1 1 1 mRNA capping enzyme DREV PF05219.7 EGC29511.1 - 0.018 13.9 0.1 0.025 13.4 0.1 1.3 1 0 0 1 1 1 0 DREV methyltransferase MetW PF07021.7 EGC29511.1 - 0.087 12.1 0.6 0.4 10.0 0.4 1.9 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW FtsJ PF01728.14 EGC29511.1 - 0.09 12.7 0.0 0.28 11.1 0.0 1.7 1 1 0 1 1 1 0 FtsJ-like methyltransferase Methyltransf_11 PF08241.7 EGC29512.1 - 2.5e-15 56.7 1.0 5.9e-15 55.5 0.0 2.1 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29512.1 - 4.9e-08 32.8 0.0 4.9e-08 32.8 0.0 2.5 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29512.1 - 6.7e-08 32.2 1.9 6.7e-08 32.2 1.3 1.8 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC29512.1 - 8.4e-07 29.2 0.5 2.6e-06 27.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29512.1 - 1.7e-05 25.2 0.1 1.7e-05 25.2 0.1 3.8 3 2 0 3 3 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29512.1 - 0.00019 21.9 0.3 0.00019 21.9 0.2 2.4 3 1 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC29512.1 - 0.006 15.7 0.0 0.011 14.8 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Vfa1 PF08432.5 EGC29512.1 - 0.068 13.1 24.3 0.13 12.2 3.0 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 Spore_coat_CotO PF14153.1 EGC29512.1 - 0.18 11.2 23.5 0.34 10.3 4.5 2.2 2 0 0 2 2 2 0 Spore coat protein CotO SR-25 PF10500.4 EGC29512.1 - 0.48 9.8 22.9 0.13 11.7 7.0 2.1 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein DUF4612 PF15389.1 EGC29512.1 - 0.52 10.9 30.7 0.13 12.8 4.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) DUF2722 PF10846.3 EGC29512.1 - 1.5 7.7 22.2 0.32 9.9 1.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2722) Neur_chan_memb PF02932.11 EGC29512.1 - 5.5 6.8 13.4 9.6 6.0 0.2 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region NARP1 PF12569.3 EGC29512.1 - 6.3 5.4 31.5 0.25 10.0 10.7 2.4 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 Rtf2 PF04641.7 EGC29512.1 - 7.3 5.7 21.5 2.5 7.2 2.1 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger SAP PF02037.22 EGC29513.1 - 3.5e-12 45.5 0.0 6.7e-07 28.6 0.1 2.7 2 0 0 2 2 2 2 SAP domain BTV_NS2 PF04514.7 EGC29513.1 - 2.4 6.9 32.7 1.3 7.7 7.7 2.3 2 0 0 2 2 2 0 Bluetongue virus non-structural protein NS2 NAD_binding_1 PF00175.16 EGC29514.1 - 2.2e-15 57.1 0.0 5.6e-15 55.8 0.0 1.7 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGC29514.1 - 3.5e-14 52.7 0.0 9.4e-14 51.3 0.0 1.7 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGC29514.1 - 2.4e-10 40.5 0.2 1.4e-08 34.8 0.0 2.8 2 1 1 3 3 3 1 Ferric reductase NAD binding domain Globin PF00042.17 EGC29514.1 - 2.7e-10 40.5 0.8 8.8e-10 38.9 0.0 2.2 2 0 0 2 2 2 1 Globin Protoglobin PF11563.3 EGC29514.1 - 0.043 13.4 0.0 0.093 12.3 0.0 1.6 1 1 0 1 1 1 0 Protoglobin Nup88 PF10168.4 EGC29516.1 - 3.7e-08 31.7 0.1 4.2e-08 31.5 0.1 1.1 1 0 0 1 1 1 1 Nuclear pore component FliS PF02561.9 EGC29516.1 - 0.2 11.5 5.0 0.064 13.1 1.4 1.6 2 0 0 2 2 2 0 Flagellar protein FliS TFIIIC_delta PF12657.2 EGC29516.1 - 0.22 11.2 1.5 0.35 10.5 1.1 1.5 1 1 0 1 1 1 0 Transcription factor IIIC subunit delta N-term Ima1_N PF09779.4 EGC29518.1 - 1.5e-08 35.1 26.5 3e-07 30.9 8.7 2.8 2 1 1 3 3 3 2 Ima1 N-terminal domain OrfB_Zn_ribbon PF07282.6 EGC29518.1 - 1.3 8.7 7.3 0.33 10.6 0.2 2.7 3 0 0 3 3 3 0 Putative transposase DNA-binding domain Mut7-C PF01927.11 EGC29518.1 - 8.5 6.3 6.8 5.3 7.0 1.0 2.5 2 0 0 2 2 2 0 Mut7-C RNAse domain DUF608 PF04685.8 EGC29519.1 - 2.1e-133 444.5 6.6 4e-133 443.6 4.6 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF608 GBA2_N PF12215.3 EGC29519.1 - 3.7e-63 213.4 3.5 3.7e-63 213.4 2.4 2.3 3 0 0 3 3 3 1 beta-Glucocerebrosidase 2 N terminal MtrE PF04206.7 EGC29519.1 - 0.32 9.9 0.0 0.59 9.0 0.0 1.3 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit E JmjC PF02373.17 EGC29520.1 - 1.2e-11 44.8 0.0 1.2e-11 44.8 0.0 5.3 3 1 2 5 5 5 1 JmjC domain, hydroxylase zf-4CXXC_R1 PF10497.4 EGC29520.1 - 1.1e-06 28.6 20.9 1.1e-06 28.6 14.5 2.7 3 0 0 3 3 3 1 Zinc-finger domain of monoamine-oxidase A repressor R1 BRCT PF00533.21 EGC29521.1 - 2.5e-14 53.1 0.4 5.7e-07 29.5 0.1 3.0 2 1 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC29521.1 - 0.00017 21.3 0.1 0.0004 20.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain RRM_6 PF14259.1 EGC29522.1 - 1.5e-05 24.8 0.0 3.4e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC29522.1 - 0.00032 20.2 0.0 0.001 18.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC29522.1 - 0.0041 16.9 0.1 0.0092 15.8 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ocnus PF05005.10 EGC29522.1 - 0.012 15.4 2.4 0.081 12.8 0.3 2.3 2 0 0 2 2 2 0 Janus/Ocnus family (Ocnus) Colicin-DNase PF12639.2 EGC29522.1 - 0.12 12.6 4.8 1 9.6 0.0 2.4 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin Retrotrans_gag PF03732.12 EGC29522.1 - 0.21 11.6 3.5 0.1 12.6 0.6 1.8 2 0 0 2 2 2 0 Retrotransposon gag protein Synaptobrevin PF00957.16 EGC29523.1 - 1.3e-12 47.0 0.5 1.9e-12 46.5 0.3 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGC29523.1 - 1.1e-05 24.8 0.0 2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain NmrA PF05368.8 EGC29524.1 - 6.1e-23 81.2 0.2 7.8e-23 80.9 0.2 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC29524.1 - 3.1e-13 50.1 0.0 4.1e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Saccharop_dh PF03435.13 EGC29524.1 - 1.9e-06 27.1 0.0 2.7e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EGC29524.1 - 1e-05 24.4 0.2 2.4e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGC29524.1 - 0.00083 18.3 0.4 0.0018 17.2 0.2 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGC29524.1 - 0.0019 17.7 0.3 0.02 14.3 0.2 2.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family TrkA_N PF02254.13 EGC29524.1 - 0.0086 16.0 0.4 0.029 14.3 0.1 2.2 2 1 1 3 3 3 1 TrkA-N domain GFO_IDH_MocA PF01408.17 EGC29524.1 - 0.017 15.6 0.0 0.036 14.5 0.0 1.5 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold KR PF08659.5 EGC29524.1 - 0.025 14.2 0.0 0.067 12.8 0.0 1.7 2 0 0 2 2 2 0 KR domain F420_oxidored PF03807.12 EGC29524.1 - 0.031 14.7 0.2 0.11 12.9 0.1 1.9 1 1 1 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Semialdhyde_dh PF01118.19 EGC29524.1 - 0.059 13.6 0.1 0.35 11.1 0.1 2.1 2 1 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Peripla_BP_4 PF13407.1 EGC29524.1 - 0.082 12.2 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 Periplasmic binding protein domain Homeobox_KN PF05920.6 EGC29525.1 - 2.4e-13 49.5 1.0 5.1e-13 48.4 0.7 1.6 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGC29525.1 - 6e-06 25.7 0.1 1.3e-05 24.7 0.1 1.5 1 0 0 1 1 1 1 Homeobox domain LIM PF00412.17 EGC29527.1 - 3.2e-12 46.3 10.5 4.4e-12 45.8 7.3 1.2 1 0 0 1 1 1 1 LIM domain C1_1 PF00130.17 EGC29527.1 - 0.15 11.7 10.8 0.83 9.4 3.7 2.3 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Fer4_21 PF14697.1 EGC29527.1 - 0.88 9.4 7.5 0.83 9.5 2.8 2.2 2 0 0 2 2 2 0 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGC29527.1 - 1.9 8.5 8.9 0.39 10.7 3.3 1.9 1 1 1 2 2 2 0 4Fe-4S dicluster domain TFIIIC_sub6 PF10419.4 EGC29529.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 TFIIIC subunit FNIP PF05725.7 EGC29530.1 - 3e-100 327.9 50.7 1.5e-12 47.2 0.6 13.9 6 4 4 13 13 13 13 FNIP Repeat LRR_5 PF13306.1 EGC29530.1 - 1.3e-06 28.1 7.3 1.4e-05 24.7 0.0 4.3 2 1 3 5 5 5 1 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC29530.1 - 9.6e-05 22.2 16.8 23 5.0 0.1 9.4 6 2 5 11 11 11 4 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC29530.1 - 0.042 13.7 3.0 45 4.0 0.0 5.1 4 3 3 7 7 7 0 Phage minor tail protein zf-AN1 PF01428.11 EGC29532.1 - 1.4e-23 82.4 25.4 1.1e-11 44.4 5.9 2.7 2 0 0 2 2 2 2 AN1-like Zinc finger S-AdoMet_synt_C PF02773.11 EGC29533.1 - 8.2e-73 242.6 0.1 1.4e-72 241.8 0.1 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, C-terminal domain S-AdoMet_synt_M PF02772.11 EGC29533.1 - 1.5e-48 163.6 0.0 2.8e-48 162.8 0.0 1.4 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, central domain S-AdoMet_synt_N PF00438.15 EGC29533.1 - 1.3e-42 144.1 0.3 2.5e-42 143.1 0.2 1.5 1 0 0 1 1 1 1 S-adenosylmethionine synthetase, N-terminal domain TPR_12 PF13424.1 EGC29534.1 - 5.9e-05 22.9 1.4 0.0012 18.7 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC29534.1 - 0.0038 16.9 0.2 0.12 12.1 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC29534.1 - 0.0052 16.6 0.4 0.023 14.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC29534.1 - 0.012 15.3 0.0 0.047 13.4 0.0 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGC29534.1 - 0.076 13.3 1.9 0.12 12.7 0.1 2.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC29534.1 - 0.12 13.0 0.1 0.54 11.0 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat MtrB PF05440.7 EGC29534.1 - 0.14 12.2 1.6 0.49 10.4 0.1 2.5 2 2 0 2 2 2 0 Tetrahydromethanopterin S-methyltransferase subunit B Lebercilin PF15619.1 EGC29534.1 - 0.85 9.0 28.0 0.051 13.0 6.4 3.7 4 0 0 4 4 4 0 Ciliary protein causing Leber congenital amaurosis disease Pkinase PF00069.20 EGC29535.1 - 2e-48 164.8 3.0 1.4e-47 162.0 0.2 2.6 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29535.1 - 6.4e-33 113.9 0.2 3.7e-23 81.9 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC29535.1 - 0.01 14.7 0.0 0.022 13.7 0.0 1.5 1 0 0 1 1 1 0 Kinase-like SH3_9 PF14604.1 EGC29536.1 - 1.6e-27 94.8 3.4 1.4e-13 50.1 0.9 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGC29536.1 - 1.4e-25 88.3 4.7 4.9e-15 54.6 0.1 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGC29536.1 - 9.2e-24 82.7 0.6 1.2e-11 43.9 0.3 2.5 2 0 0 2 2 2 2 Variant SH3 domain DUF1241 PF06840.6 EGC29536.1 - 0.00055 19.2 3.4 0.00055 19.2 2.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) AAA_27 PF13514.1 EGC29536.1 - 0.032 11.9 11.8 0.27 8.8 5.0 2.3 2 0 0 2 2 2 0 AAA domain Tropomyosin_1 PF12718.2 EGC29536.1 - 0.041 13.7 0.4 0.041 13.7 0.3 2.9 2 1 0 2 2 2 0 Tropomyosin like HR1 PF02185.11 EGC29536.1 - 0.06 13.1 29.1 0.7 9.6 0.2 3.9 3 1 0 3 3 3 0 Hr1 repeat IncA PF04156.9 EGC29536.1 - 0.061 12.9 20.1 1.1 8.7 0.3 2.9 2 1 1 3 3 3 0 IncA protein FliT PF05400.8 EGC29536.1 - 0.11 12.8 7.5 3.8 7.9 1.5 2.8 2 0 0 2 2 2 0 Flagellar protein FliT Baculo_PEP_C PF04513.7 EGC29536.1 - 0.16 11.8 8.5 0.63 9.8 0.3 3.0 2 1 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus PilJ PF13675.1 EGC29536.1 - 0.21 11.9 3.1 14 6.0 0.4 2.8 2 1 0 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF2937 PF11157.3 EGC29536.1 - 0.21 10.8 3.3 0.57 9.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2937) DUF1192 PF06698.6 EGC29536.1 - 0.24 11.2 2.2 22 4.9 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF1192) BLOC1_2 PF10046.4 EGC29536.1 - 0.3 11.2 19.0 0.44 10.6 2.7 4.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DivIC PF04977.10 EGC29536.1 - 0.34 10.4 28.2 0.2 11.1 0.8 4.7 4 1 1 5 5 5 0 Septum formation initiator WXG100 PF06013.7 EGC29536.1 - 0.55 10.2 4.7 6.7 6.8 0.3 3.5 2 1 0 3 3 3 0 Proteins of 100 residues with WXG Syntaxin-6_N PF09177.6 EGC29536.1 - 0.85 10.0 13.2 3.7 8.0 0.2 3.7 2 1 1 3 3 3 0 Syntaxin 6, N-terminal Reo_sigmaC PF04582.7 EGC29536.1 - 1.2 8.2 7.6 4.6 6.3 0.3 3.1 2 1 1 3 3 3 0 Reovirus sigma C capsid protein Imm5 PF14423.1 EGC29536.1 - 1.6 8.3 6.8 0.18 11.4 0.3 2.6 3 1 1 4 4 3 0 Immunity protein Imm5 APG6 PF04111.7 EGC29536.1 - 3.3 6.6 24.0 9.8 5.1 12.3 2.6 2 1 0 2 2 2 0 Autophagy protein Apg6 LURAP PF14854.1 EGC29536.1 - 4.2 7.1 12.1 3.2 7.5 0.8 3.3 2 1 1 3 3 3 0 Leucine rich adaptor protein CENP-Q PF13094.1 EGC29536.1 - 4.3 7.3 22.1 6.6 6.7 2.1 3.8 2 1 1 3 3 3 0 CENP-Q, a CENPA-CAD centromere complex subunit Tnp_P_element PF12017.3 EGC29536.1 - 7.4 5.7 11.8 5.3 6.1 1.2 3.3 2 1 1 3 3 3 0 Transposase protein DUF2203 PF09969.4 EGC29536.1 - 7.7 6.7 17.5 10 6.3 2.1 3.5 2 1 1 3 3 3 0 Uncharacterized conserved protein (DUF2203) DUF4140 PF13600.1 EGC29536.1 - 8.1 6.9 16.6 6.6 7.2 0.2 4.7 2 1 3 5 5 5 0 N-terminal domain of unknown function (DUF4140) MMR_HSR1 PF01926.18 EGC29537.1 - 3.2e-06 27.0 4.2 5.7e-06 26.2 0.5 2.9 3 1 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC29537.1 - 0.0022 17.8 5.5 0.33 10.7 0.1 3.6 3 1 1 4 4 4 2 Dynamin family Trypan_PARP PF05887.6 EGC29538.1 - 0.46 10.3 2.4 0.56 10.0 1.7 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF4463 PF14703.1 EGC29538.1 - 1.3 9.6 3.3 2.1 8.9 2.3 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF4463) Chitin_bind_3 PF03067.10 EGC29539.1 - 2.3e-06 28.0 1.2 6e-06 26.6 0.3 1.8 1 1 1 2 2 2 1 Chitin binding domain IMS PF00817.15 EGC29540.1 - 0.045 13.5 0.0 0.11 12.3 0.0 1.7 2 0 0 2 2 2 0 impB/mucB/samB family z-alpha PF02295.12 EGC29541.1 - 0.076 12.8 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Adenosine deaminase z-alpha domain HEAT_2 PF13646.1 EGC29543.1 - 6.5e-38 128.8 10.6 8.3e-17 61.2 0.2 3.2 2 1 1 3 3 3 3 HEAT repeats HEAT_PBS PF03130.11 EGC29543.1 - 2.6e-27 92.4 0.2 5.5e-05 23.2 0.0 6.5 6 0 0 6 6 6 5 PBS lyase HEAT-like repeat HEAT PF02985.17 EGC29543.1 - 1e-15 56.2 6.0 0.014 15.4 0.0 6.4 6 0 0 6 6 6 4 HEAT repeat HEAT_EZ PF13513.1 EGC29543.1 - 4.1e-09 36.6 8.2 0.043 14.3 0.1 5.7 5 1 2 7 7 7 4 HEAT-like repeat Arm PF00514.18 EGC29543.1 - 0.0013 18.4 1.3 0.63 9.9 0.0 3.5 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EGC29543.1 - 0.02 14.8 0.0 0.065 13.1 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) C2 PF00168.25 EGC29544.1 - 2.1e-10 40.2 0.1 3.9e-10 39.4 0.1 1.4 1 0 0 1 1 1 1 C2 domain SNF2_N PF00176.18 EGC29545.1 - 4.9e-39 133.8 0.0 4.9e-39 133.8 0.0 3.1 2 1 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC29545.1 - 1.8e-08 34.1 0.5 5.2e-08 32.6 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Trypan_PARP PF05887.6 EGC29545.1 - 0.22 11.3 14.5 0.47 10.2 10.1 1.5 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Ependymin PF00811.13 EGC29546.1 - 1.8e-06 27.6 0.4 1.8e-06 27.6 0.2 1.9 2 0 0 2 2 2 1 Ependymin zf-C3HC4_3 PF13920.1 EGC29547.1 - 3.6e-08 32.9 7.9 6.5e-08 32.1 5.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29547.1 - 4.8e-08 32.5 9.6 1.5e-07 30.9 6.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC29547.1 - 4.5e-07 29.6 9.1 7.9e-07 28.8 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC29547.1 - 8.6e-06 25.7 6.0 2.3e-05 24.4 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC29547.1 - 3.3e-05 23.8 9.7 6.3e-05 22.9 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29547.1 - 0.0011 18.6 9.4 0.0022 17.6 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29547.1 - 0.0089 15.8 8.5 0.031 14.1 5.9 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING OppC_N PF12911.2 EGC29547.1 - 0.028 13.7 0.7 0.2 11.0 0.5 2.5 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Rab5ip PF07019.7 EGC29547.1 - 0.11 12.5 0.1 0.25 11.4 0.1 1.6 1 0 0 1 1 1 0 Rab5-interacting protein (Rab5ip) zf-RING_UBOX PF13445.1 EGC29547.1 - 0.23 11.2 3.3 0.79 9.4 2.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGC29547.1 - 0.58 9.7 10.8 5.5 6.6 7.4 2.4 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC29547.1 - 0.81 9.5 5.7 2.2 8.1 3.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1379 PF07126.7 EGC29548.1 - 0.052 12.9 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1379) FAD_binding_4 PF01565.18 EGC29549.1 - 2e-25 88.8 0.1 4e-25 87.9 0.1 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC29549.1 - 2.8e-06 27.1 0.1 9.2e-06 25.4 0.1 1.9 1 0 0 1 1 1 1 Berberine and berberine like Innate_immun PF12782.2 EGC29549.1 - 3 6.9 9.3 4 6.5 6.5 1.1 1 0 0 1 1 1 0 Invertebrate innate immunity transcript family bZIP_C PF12498.3 EGC29549.1 - 9.4 7.5 18.1 13 7.0 0.0 2.6 2 0 0 2 2 2 0 Basic leucine-zipper C terminal Ank_2 PF12796.2 EGC29550.1 - 4.6e-27 94.1 0.0 8.2e-16 58.1 0.0 2.0 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC29550.1 - 3e-26 89.8 0.1 1.6e-07 30.7 0.0 4.2 4 1 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGC29550.1 - 6.7e-22 75.3 0.0 1.7e-06 27.6 0.0 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGC29550.1 - 9.4e-20 70.2 0.0 4.6e-06 26.6 0.0 3.2 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC29550.1 - 8.2e-19 67.6 0.3 2.4e-07 31.0 0.0 4.2 1 1 2 4 4 4 3 Ankyrin repeats (many copies) RTA1 PF04479.8 EGC29551.1 - 6.9e-33 114.0 2.3 9.9e-33 113.5 1.6 1.2 1 0 0 1 1 1 1 RTA1 like protein Claudin_2 PF13903.1 EGC29551.1 - 3.2 7.4 9.5 0.17 11.5 0.3 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DCX PF03607.12 EGC29552.1 - 0.049 13.2 0.0 0.067 12.7 0.0 1.3 1 0 0 1 1 1 0 Doublecortin MSC PF09402.5 EGC29553.1 - 1.1e-43 149.2 0.1 1.1e-43 149.2 0.1 2.9 3 1 1 4 4 4 1 Man1-Src1p-C-terminal domain DUF912 PF06024.7 EGC29554.1 - 0.00021 21.3 1.4 0.00033 20.6 0.0 1.9 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EGC29554.1 - 0.0034 17.0 0.6 0.0034 17.0 0.4 2.4 2 1 0 2 2 2 1 TMEM154 protein family Mito_fiss_reg PF05308.6 EGC29554.1 - 0.088 12.1 9.8 0.096 12.0 1.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Dicty_REP PF05086.7 EGC29554.1 - 0.64 7.7 7.6 0.12 10.1 2.5 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EGC29554.1 - 2.8 5.7 8.8 3.8 5.3 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mem_trans PF03547.13 EGC29554.1 - 9.6 4.3 7.4 24 3.0 5.1 1.7 1 1 0 1 1 1 0 Membrane transport protein Laminin_EGF PF00053.19 EGC29555.1 - 0.0091 15.9 23.1 0.17 11.8 7.1 2.7 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC29555.1 - 0.014 15.5 16.3 0.014 15.5 11.3 3.2 3 0 0 3 3 3 0 EGF-like domain Peptidase_M22 PF00814.20 EGC29555.1 - 0.16 11.4 0.0 0.28 10.6 0.0 1.3 1 0 0 1 1 1 0 Glycoprotease family PCAF_N PF06466.6 EGC29556.1 - 0.0036 16.6 0.0 0.0068 15.7 0.0 1.4 1 0 0 1 1 1 1 PCAF (P300/CBP-associated factor) N-terminal domain DUF3793 PF12672.2 EGC29556.1 - 0.022 14.3 0.1 0.04 13.5 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3793) PH PF00169.24 EGC29558.1 - 6.5e-08 32.7 6.9 6.5e-08 32.7 4.8 3.0 2 2 0 2 2 2 1 PH domain PH_3 PF14593.1 EGC29558.1 - 0.034 14.0 1.1 0.034 14.0 0.8 2.6 2 0 0 2 2 2 0 PH domain TAS2R PF05296.8 EGC29558.1 - 4.5 6.0 9.6 0.067 12.0 0.9 2.0 2 0 0 2 2 2 0 Mammalian taste receptor protein (TAS2R) EAP30 PF04157.11 EGC29558.1 - 6.4 5.8 18.0 0.057 12.5 6.6 2.0 2 0 0 2 2 2 0 EAP30/Vps36 family Mito_carr PF00153.22 EGC29559.1 - 9.1e-67 220.8 4.4 3.4e-26 90.7 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF4257 PF14074.1 EGC29559.1 - 0.0026 17.3 0.2 0.21 11.2 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4257) HypA PF01155.14 EGC29560.1 - 0.087 12.5 11.1 0.25 11.0 0.2 3.6 1 1 1 3 3 3 0 Hydrogenase expression/synthesis hypA family zinc_ribbon_6 PF14599.1 EGC29560.1 - 0.2 11.5 0.1 0.2 11.5 0.1 3.8 4 0 0 4 4 4 0 Zinc-ribbon DNA_RNApol_7kD PF03604.8 EGC29560.1 - 0.23 10.9 0.1 0.23 10.9 0.1 3.9 5 0 0 5 5 5 0 DNA directed RNA polymerase, 7 kDa subunit Stc1 PF12898.2 EGC29560.1 - 2 8.5 11.4 6.6 6.8 2.0 3.1 2 1 0 2 2 2 0 Stc1 domain Elf1 PF05129.8 EGC29560.1 - 5.6 6.7 15.5 0.2 11.3 0.1 4.7 3 2 2 5 5 5 0 Transcription elongation factor Elf1 like zf-CSL PF05207.8 EGC29561.1 - 0.055 12.9 3.7 0.46 10.0 0.0 2.9 2 0 0 2 2 2 0 CSL zinc finger Ricin_B_lectin PF00652.17 EGC29563.1 - 1.7e-09 37.7 3.4 4.2e-09 36.4 2.3 1.7 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain Ras PF00071.17 EGC29564.1 - 1e-43 148.5 0.0 1.3e-43 148.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC29564.1 - 1.5e-13 51.2 0.0 3e-13 50.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC29564.1 - 0.00012 21.3 0.0 0.00017 20.8 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC29564.1 - 0.0032 16.9 0.0 0.032 13.6 0.0 2.2 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC29564.1 - 0.042 13.3 0.0 0.45 10.0 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DNA_RNApol_7kD PF03604.8 EGC29567.1 - 2e-07 30.3 2.1 0.0018 17.6 0.1 2.4 2 0 0 2 2 2 2 DNA directed RNA polymerase, 7 kDa subunit Coiled PF05710.7 EGC29567.1 - 0.00072 19.9 0.1 1.7 9.1 0.0 2.1 2 0 0 2 2 2 2 Coiled coil CpXC PF14353.1 EGC29567.1 - 0.0012 18.7 1.6 0.29 11.0 0.3 2.2 2 0 0 2 2 2 2 CpXC protein zinc_ribbon_6 PF14599.1 EGC29567.1 - 0.0014 18.4 1.3 0.068 12.9 0.1 2.4 2 0 0 2 2 2 1 Zinc-ribbon DUF678 PF05077.7 EGC29567.1 - 0.0016 18.3 1.6 0.31 11.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF678) TF_Zn_Ribbon PF08271.7 EGC29567.1 - 0.0028 16.9 0.5 1.7 8.0 0.0 2.4 2 0 0 2 2 2 2 TFIIB zinc-binding Ribosomal_S27e PF01667.12 EGC29567.1 - 0.003 17.0 1.3 1 8.9 0.2 2.3 2 0 0 2 2 2 1 Ribosomal protein S27 Tnp_zf-ribbon_2 PF13842.1 EGC29567.1 - 0.01 16.2 5.9 1.1 9.7 0.2 2.4 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon Evr1_Alr PF04777.8 EGC29567.1 - 0.012 15.4 4.0 0.052 13.4 0.6 2.3 1 1 1 2 2 2 0 Erv1 / Alr family Zn-ribbon_8 PF09723.5 EGC29567.1 - 0.013 15.4 0.5 4.5 7.2 0.0 2.4 2 0 0 2 2 2 0 Zinc ribbon domain ADK_lid PF05191.9 EGC29567.1 - 0.013 15.0 0.1 0.94 9.1 0.0 2.3 2 0 0 2 2 2 0 Adenylate kinase, active site lid GFA PF04828.9 EGC29567.1 - 0.021 14.7 1.5 2.1 8.3 0.1 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Stc1 PF12898.2 EGC29567.1 - 0.021 14.8 1.7 4.7 7.3 0.1 2.3 2 0 0 2 2 2 0 Stc1 domain Lar_restr_allev PF14354.1 EGC29567.1 - 0.029 14.6 0.6 0.76 10.1 0.4 2.2 1 1 0 1 1 1 0 Restriction alleviation protein Lar zf-BED PF02892.10 EGC29567.1 - 0.059 13.1 3.2 3.7 7.3 0.3 2.3 2 0 0 2 2 2 0 BED zinc finger zf-trcl PF13451.1 EGC29567.1 - 0.063 12.9 1.6 7.9 6.1 0.0 2.6 2 0 0 2 2 2 0 Probable zinc-binding domain DZR PF12773.2 EGC29567.1 - 0.064 13.0 4.3 0.3 10.9 3.0 1.9 1 1 1 2 2 2 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGC29567.1 - 0.098 11.8 1.4 8.2 5.7 0.2 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Ribosomal_L37e PF01907.14 EGC29567.1 - 0.1 12.4 0.8 8.5 6.2 0.1 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e zinc_ribbon_5 PF13719.1 EGC29567.1 - 0.13 11.8 2.8 6.6 6.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain HypA PF01155.14 EGC29567.1 - 0.15 11.7 3.4 2.8 7.6 2.3 2.2 1 1 0 1 1 1 0 Hydrogenase expression/synthesis hypA family Mu-like_Com PF10122.4 EGC29567.1 - 0.16 11.0 2.6 3.5 6.7 0.2 2.3 2 0 0 2 2 2 0 Mu-like prophage protein Com TFIIS_C PF01096.13 EGC29567.1 - 0.17 11.5 2.2 7.7 6.2 0.1 2.5 2 0 0 2 2 2 0 Transcription factor S-II (TFIIS) zf-TRAF PF02176.13 EGC29567.1 - 0.19 12.1 3.6 0.55 10.6 0.3 2.2 2 0 0 2 2 2 0 TRAF-type zinc finger zinc_ribbon_4 PF13717.1 EGC29567.1 - 0.22 11.2 3.6 6.8 6.4 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Elf1 PF05129.8 EGC29567.1 - 0.29 10.8 8.0 0.39 10.4 1.5 2.3 1 1 1 2 2 2 0 Transcription elongation factor Elf1 like DUF951 PF06107.6 EGC29567.1 - 0.42 10.1 2.6 4.8 6.7 0.3 2.3 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF951) zinc_ribbon_2 PF13240.1 EGC29567.1 - 0.49 9.9 4.7 9.3 5.8 0.4 2.4 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EGC29567.1 - 0.76 9.5 3.4 14 5.4 0.1 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 zf-C3HC PF07967.8 EGC29567.1 - 1.3 8.7 6.7 5.4 6.7 0.4 2.2 1 1 1 2 2 2 0 C3HC zinc finger-like MU117 PF15474.1 EGC29567.1 - 1.5 9.3 6.3 7 7.2 4.2 1.9 1 1 0 1 1 1 0 Meiotically up-regulated gene family zf-CCHC_6 PF15288.1 EGC29567.1 - 1.6 8.4 7.2 9.7 5.9 0.6 2.4 2 0 0 2 2 2 0 Zinc knuckle FeS PF04060.8 EGC29567.1 - 2.9 7.5 5.5 10 5.7 0.5 2.3 2 0 0 2 2 2 0 Putative Fe-S cluster Zn_ribbon_recom PF13408.1 EGC29567.1 - 4.9 7.4 14.1 1.1 9.5 0.7 3.2 2 1 1 3 3 3 0 Recombinase zinc beta ribbon domain RasGEF PF00617.14 EGC29568.1 - 1.3e-60 204.3 1.7 4.8e-60 202.5 1.2 2.1 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC29568.1 - 2.2e-21 75.9 0.4 2.2e-21 75.9 0.3 3.8 3 1 0 3 3 3 1 RasGEF N-terminal motif MIP-T3 PF10243.4 EGC29568.1 - 0.87 7.9 68.0 0.83 8.0 18.1 2.2 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 GTP_EFTU PF00009.22 EGC29569.1 - 1.3e-53 181.2 0.1 2e-53 180.6 0.1 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGC29569.1 - 6.5e-20 70.7 0.0 2e-19 69.2 0.0 1.9 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC29569.1 - 7.1e-08 32.4 2.8 5.8e-07 29.5 0.9 2.8 2 0 0 2 2 2 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC29569.1 - 2.9e-06 27.2 0.1 7.5e-06 25.8 0.1 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC29569.1 - 1.1e-05 25.8 0.1 2.7e-05 24.6 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Septin PF00735.13 EGC29569.1 - 0.00052 19.1 0.1 0.0013 17.7 0.1 1.6 1 0 0 1 1 1 1 Septin SRPRB PF09439.5 EGC29569.1 - 0.00076 18.7 0.0 0.0022 17.2 0.0 1.9 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit EFG_II PF14492.1 EGC29569.1 - 0.0015 18.3 0.0 0.0032 17.2 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II FeoB_N PF02421.13 EGC29569.1 - 0.0052 16.0 0.0 0.066 12.4 0.0 2.6 2 1 0 2 2 2 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGC29569.1 - 0.0066 16.2 0.0 0.16 11.7 0.0 2.2 1 1 1 2 2 2 1 Dynamin family ubiquitin PF00240.18 EGC29570.1 - 2.8e-07 29.8 0.0 5.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC29570.1 - 0.0094 15.6 0.1 0.019 14.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like RabGAP-TBC PF00566.13 EGC29571.1 - 9.5e-50 169.0 4.0 9.5e-50 169.0 2.7 3.9 3 2 0 3 3 3 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 EGC29571.1 - 3.3e-10 38.5 4.5 6.2e-06 25.1 0.1 3.9 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGC29571.1 - 6.2e-10 39.0 2.6 9.9e-09 35.2 0.2 2.7 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC29571.1 - 3.3e-08 32.7 4.9 6.3e-05 22.5 0.1 3.7 3 0 0 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EGC29571.1 - 1.4e-07 30.5 5.6 3.3e-06 26.1 0.3 3.3 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EGC29571.1 - 0.00013 21.4 3.2 0.017 14.7 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain pair KTSC PF13619.1 EGC29572.1 - 0.015 14.8 2.2 0.023 14.3 0.2 2.3 3 0 0 3 3 3 0 KTSC domain Vps36_ESCRT-II PF11605.3 EGC29572.1 - 0.054 13.3 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Vacuolar protein sorting protein 36 Vps36 NDK PF00334.14 EGC29573.1 - 3e-51 172.7 0.0 4.7e-51 172.1 0.0 1.3 1 0 0 1 1 1 1 Nucleoside diphosphate kinase PHP PF02811.14 EGC29574.1 - 2.5e-08 33.9 0.0 3.3e-08 33.5 0.0 1.3 1 0 0 1 1 1 1 PHP domain DUF1482 PF07358.6 EGC29574.1 - 0.049 13.2 0.1 0.12 11.9 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1482) Ost4 PF10215.4 EGC29574.1 - 0.064 12.7 1.2 0.15 11.5 0.8 1.7 1 0 0 1 1 1 0 Oligosaccaryltransferase S-AdoMet_synt_C PF02773.11 EGC29574.1 - 0.1 12.3 0.0 0.22 11.2 0.0 1.5 1 0 0 1 1 1 0 S-adenosylmethionine synthetase, C-terminal domain Sigma_reg_N PF13800.1 EGC29574.1 - 0.96 9.5 5.3 0.22 11.5 0.2 2.3 2 0 0 2 2 2 0 Sigma factor regulator N-terminal zf-RING_2 PF13639.1 EGC29575.1 - 1.3e-09 37.7 15.5 2.3e-09 36.9 10.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29575.1 - 5.2e-08 32.4 14.2 9e-08 31.6 9.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29575.1 - 2.3e-06 27.5 9.7 8.2e-06 25.8 6.7 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC29575.1 - 5e-05 23.2 18.3 8.9e-05 22.4 12.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29575.1 - 0.00017 21.1 18.9 0.00037 20.0 13.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29575.1 - 0.012 15.3 16.6 0.025 14.2 11.5 1.6 1 0 0 1 1 1 0 zinc-RING finger domain TFIIA PF03153.8 EGC29575.1 - 0.73 9.6 58.3 0.0069 16.3 30.7 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit MAP7 PF05672.6 EGC29575.1 - 0.99 8.7 55.2 0.54 9.6 12.4 2.5 2 0 0 2 2 2 0 MAP7 (E-MAP-115) family zf-RING_UBOX PF13445.1 EGC29575.1 - 0.99 9.1 9.6 4.2 7.1 6.7 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC29575.1 - 6.9 6.6 15.8 26 4.7 10.9 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Erf4 PF10256.4 EGC29576.1 - 0.095 12.5 11.6 0.58 10.0 0.4 3.5 3 1 0 3 3 3 0 Golgin subfamily A member 7/ERF4 family EGF_2 PF07974.8 EGC29577.1 - 0.02 15.0 13.2 0.05 13.7 9.1 1.7 1 0 0 1 1 1 0 EGF-like domain zf-TRAF PF02176.13 EGC29578.1 - 9.1e-06 25.9 2.7 9.1e-06 25.9 1.8 3.3 2 2 1 3 3 3 2 TRAF-type zinc finger DM PF00751.13 EGC29578.1 - 0.002 17.5 1.1 0.002 17.5 0.8 3.4 2 2 1 3 3 3 2 DM DNA binding domain Sina PF03145.11 EGC29578.1 - 0.0021 17.7 4.7 0.23 11.0 1.4 2.5 1 1 1 2 2 2 2 Seven in absentia protein family DRP PF06044.7 EGC29578.1 - 0.0096 14.9 5.4 0.011 14.7 3.7 1.4 1 1 0 1 1 1 1 Dam-replacing family zf-C3HC4_2 PF13923.1 EGC29578.1 - 0.021 14.8 6.8 0.021 14.8 4.7 2.9 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-U11-48K PF05253.7 EGC29578.1 - 0.36 10.5 3.6 28 4.5 0.3 3.4 3 0 0 3 3 3 0 U11-48K-like CHHC zinc finger Prok-RING_2 PF14445.1 EGC29578.1 - 1.9 8.5 7.8 1.1 9.2 2.8 2.3 2 0 0 2 2 2 0 Prokaryotic RING finger family 2 C1_3 PF07649.7 EGC29578.1 - 8.2 6.5 8.0 2.5 8.2 0.5 3.2 3 0 0 3 3 3 0 C1-like domain CwfJ_C_1 PF04677.10 EGC29579.1 - 3.7e-34 116.9 0.4 8.1e-34 115.9 0.3 1.5 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGC29579.1 - 5.4e-20 71.7 0.4 5.4e-20 71.7 0.3 3.9 4 0 0 4 4 4 1 Protein similar to CwfJ C-terminus 2 UPF0052 PF01933.13 EGC29579.1 - 0.031 13.5 1.0 0.076 12.3 0.1 1.9 1 1 0 1 1 1 0 Uncharacterised protein family UPF0052 DUF3184 PF11380.3 EGC29580.1 - 0.00045 18.2 0.4 0.18 9.7 0.1 3.0 2 1 1 3 3 3 3 Protein of unknown function (DUF3184) DUF1390 PF07150.6 EGC29580.1 - 8.1 5.7 10.4 15 4.8 7.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) ATP-synt_8 PF00895.15 EGC29580.1 - 8.4 6.6 12.0 1.1 9.5 5.0 2.0 2 0 0 2 2 2 0 ATP synthase protein 8 PAH PF02671.16 EGC29581.1 - 0.0062 16.1 0.6 0.045 13.3 0.3 2.5 2 1 0 2 2 2 1 Paired amphipathic helix repeat DUF1132 PF06575.7 EGC29582.1 - 0.76 10.1 3.8 0.73 10.1 2.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1132) Acyl_transf_1 PF00698.16 EGC29583.1 - 8.7e-18 64.7 0.0 1.1e-17 64.4 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DUF1951 PF09188.5 EGC29583.1 - 0.075 12.9 1.4 0.21 11.5 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1951) DUF812 PF05667.6 EGC29584.1 - 1.5e-189 631.3 32.4 1.7e-189 631.1 22.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Occludin_ELL PF07303.8 EGC29584.1 - 0.25 12.0 40.8 1 10.1 6.1 5.1 3 1 3 6 6 6 0 Occludin homology domain Med4 PF10018.4 EGC29584.1 - 0.88 8.9 35.0 0.46 9.8 6.6 3.5 3 0 0 3 3 3 0 Vitamin-D-receptor interacting Mediator subunit 4 Tropomyosin_1 PF12718.2 EGC29584.1 - 1.9 8.3 42.7 4.2 7.2 15.1 3.4 1 1 2 3 3 3 0 Tropomyosin like Rotamase PF00639.16 EGC29584.1 - 7.6 7.3 9.8 4.7 8.0 1.1 3.4 2 0 0 2 2 2 0 PPIC-type PPIASE domain ThiF PF00899.16 EGC29585.1 - 8.7e-15 54.7 0.2 2.9e-14 53.0 0.1 1.8 2 0 0 2 2 2 1 ThiF family KaiC PF06745.8 EGC29585.1 - 0.023 13.8 0.6 0.61 9.1 0.0 2.2 2 0 0 2 2 2 0 KaiC DUF1370 PF07114.6 EGC29585.1 - 0.028 13.6 0.0 0.057 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1370) HCO3_cotransp PF00955.16 EGC29586.1 - 0.42 9.2 2.1 0.48 9.0 1.5 1.0 1 0 0 1 1 1 0 HCO3- transporter family Mito_carr PF00153.22 EGC29587.1 - 2.8e-65 216.0 0.3 3.3e-22 77.9 0.0 3.9 2 1 1 3 3 3 3 Mitochondrial carrier protein DUF4095 PF13338.1 EGC29587.1 - 0.14 12.3 0.1 0.99 9.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4095) 5TM-5TMR_LYT PF07694.7 EGC29588.1 - 0.0014 17.9 2.3 0.0025 17.1 1.6 1.5 1 1 0 1 1 1 1 5TMR of 5TMR-LYT Tim17 PF02466.14 EGC29588.1 - 0.0055 16.7 0.0 0.0083 16.1 0.0 1.4 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family UPF0254 PF06787.6 EGC29588.1 - 0.029 13.8 0.0 0.041 13.3 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0254) Notch PF00066.12 EGC29590.1 - 7.3e-17 61.3 36.9 1e-08 35.2 10.5 2.6 2 0 0 2 2 2 2 LNR domain DUF3184 PF11380.3 EGC29590.1 - 7.6e-07 27.4 0.1 0.00048 18.2 0.0 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3184) TPT PF03151.11 EGC29591.1 - 3.1e-11 43.1 14.5 3.1e-11 43.1 10.1 2.6 2 1 0 2 2 2 1 Triose-phosphate Transporter family Methyltransf_16 PF10294.4 EGC29592.1 - 1.3e-13 50.7 3.1 1.4e-08 34.3 0.1 2.2 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_12 PF08242.7 EGC29592.1 - 0.35 11.3 10.6 0.44 11.0 4.0 3.0 2 1 0 2 2 2 0 Methyltransferase domain HCaRG PF07258.9 EGC29593.1 - 4.4e-33 114.3 0.6 5e-33 114.1 0.4 1.0 1 0 0 1 1 1 1 HCaRG protein K-box PF01486.12 EGC29593.1 - 0.012 15.3 0.2 0.03 14.0 0.2 1.6 1 0 0 1 1 1 0 K-box region EF-hand_1 PF00036.27 EGC29594.1 - 1.5e-18 64.6 10.6 1.7e-06 26.8 0.0 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC29594.1 - 4.3e-18 63.5 4.8 2.3e-06 26.9 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EGC29594.1 - 7.4e-16 58.0 4.3 2.1e-08 34.1 1.7 2.4 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC29594.1 - 3.7e-12 45.6 6.7 4.2e-07 29.4 0.5 4.4 2 1 2 4 4 4 4 EF-hand domain pair EF-hand_5 PF13202.1 EGC29594.1 - 7e-12 44.1 11.7 1.9e-06 26.9 0.1 4.4 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 EGC29594.1 - 0.00034 20.3 4.4 0.0031 17.2 0.4 3.0 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGC29594.1 - 0.00035 20.5 3.2 0.38 10.7 0.3 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC29594.1 - 0.0022 17.6 8.2 0.37 10.5 0.4 3.9 4 1 0 4 4 4 1 EF hand EF-hand_9 PF14658.1 EGC29594.1 - 0.0039 17.0 0.0 0.015 15.2 0.0 1.9 2 0 0 2 2 2 1 EF-hand domain Peptidase_S46 PF10459.4 EGC29594.1 - 0.021 13.2 0.4 0.025 12.9 0.3 1.1 1 0 0 1 1 1 0 Peptidase S46 UPF0137 PF03677.8 EGC29594.1 - 0.021 14.3 2.6 0.096 12.2 0.4 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0137) RST PF12174.3 EGC29594.1 - 0.075 12.8 0.4 2.7 7.8 0.0 2.9 3 0 0 3 3 3 0 RCD1-SRO-TAF4 (RST) plant domain AMP-binding PF00501.23 EGC29595.1 - 1.6e-70 237.6 0.0 1.9e-70 237.3 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC29595.1 - 0.00015 22.6 0.0 0.00031 21.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Chorein_N PF12624.2 EGC29598.1 - 6.7e-39 132.0 3.8 6.7e-39 132.0 2.7 7.5 10 0 0 10 10 10 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC29598.1 - 2.5e-09 37.1 0.0 1.7e-08 34.5 0.0 2.4 2 0 0 2 2 2 1 ATG C terminal domain TraG_N PF07916.6 EGC29599.1 - 4.8 5.5 9.9 10 4.4 6.9 1.5 1 0 0 1 1 1 0 TraG-like protein, N-terminal region LytR_cpsA_psr PF03816.9 EGC29600.1 - 0.11 12.4 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 Cell envelope-related transcriptional attenuator domain GCD14 PF08704.5 EGC29601.1 - 1e-101 339.6 0.0 1.3e-101 339.2 0.0 1.1 1 0 0 1 1 1 1 tRNA methyltransferase complex GCD14 subunit Methyltransf_31 PF13847.1 EGC29601.1 - 1.8e-08 34.0 0.0 2.8e-08 33.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29601.1 - 4e-07 30.5 0.0 6.3e-07 29.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC29601.1 - 3.1e-06 26.8 0.0 5.8e-06 25.9 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_26 PF13659.1 EGC29601.1 - 0.0001 22.3 0.0 0.00015 21.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGC29601.1 - 0.00011 22.9 0.0 0.00019 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC29601.1 - 0.00012 21.4 0.0 0.00021 20.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain RrnaAD PF00398.15 EGC29601.1 - 0.00055 19.0 0.0 0.0009 18.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Fibrillarin PF01269.12 EGC29601.1 - 0.0013 17.6 0.0 0.0043 15.9 0.0 1.8 1 1 0 1 1 1 1 Fibrillarin Methyltransf_3 PF01596.12 EGC29601.1 - 0.0023 17.0 0.0 0.008 15.2 0.0 1.8 2 0 0 2 2 2 1 O-methyltransferase Gcd10p PF04189.8 EGC29601.1 - 0.0076 15.4 0.1 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 Gcd10p family PrmA PF06325.8 EGC29601.1 - 0.012 14.7 0.0 0.017 14.2 0.0 1.3 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Ubie_methyltran PF01209.13 EGC29601.1 - 0.026 13.6 0.0 0.035 13.2 0.0 1.3 1 0 0 1 1 1 0 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGC29601.1 - 0.038 14.4 0.0 0.088 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MMR_HSR1 PF01926.18 EGC29602.1 - 1.2e-13 50.9 0.1 4.6e-13 49.1 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC29602.1 - 6.1e-05 22.3 0.5 0.00016 20.9 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B DUF258 PF03193.11 EGC29602.1 - 0.0024 17.0 0.0 0.0063 15.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC29602.1 - 0.0037 17.7 0.6 0.13 12.7 0.0 2.6 2 0 0 2 2 2 1 Miro-like protein DUF2215 PF10225.4 EGC29603.1 - 0.098 12.0 0.0 0.098 12.0 0.0 2.7 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2215) FAM176 PF14851.1 EGC29603.1 - 0.16 11.6 6.0 0.31 10.7 0.0 2.9 2 0 0 2 2 2 0 FAM176 family PIRT PF15099.1 EGC29603.1 - 0.24 10.6 0.0 0.24 10.6 0.0 2.6 3 0 0 3 3 3 0 Phosphoinositide-interacting protein family TMEM51 PF15345.1 EGC29603.1 - 0.26 10.9 0.0 0.26 10.9 0.0 2.6 2 0 0 2 2 2 0 Transmembrane protein 51 Thioredoxin PF00085.15 EGC29604.1 - 1.2e-52 175.9 5.7 1.3e-27 95.4 0.0 4.1 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EGC29604.1 - 1.1e-38 132.9 13.3 1.8e-33 115.8 2.2 3.1 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGC29604.1 - 8.5e-11 41.7 0.3 0.0012 18.8 0.0 3.7 3 1 1 4 4 4 2 Thioredoxin-like Calsequestrin PF01216.12 EGC29604.1 - 6.7e-10 38.2 4.4 6.7e-10 38.2 3.1 1.6 2 0 0 2 2 2 1 Calsequestrin Thioredoxin_2 PF13098.1 EGC29604.1 - 4.1e-09 36.6 6.8 0.00073 19.7 0.1 4.8 3 2 0 3 3 3 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC29604.1 - 4.4e-09 36.3 4.2 0.00026 21.0 0.0 4.7 3 2 0 4 4 4 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EGC29604.1 - 0.00092 18.7 0.1 0.45 10.0 0.0 2.8 3 0 0 3 3 3 2 Thioredoxin Glutaredoxin PF00462.19 EGC29604.1 - 0.015 15.2 0.7 2.1 8.3 0.0 3.2 3 1 0 3 3 3 0 Glutaredoxin Thioredoxin_5 PF13743.1 EGC29604.1 - 0.16 11.4 2.9 12 5.3 0.0 3.8 2 2 2 4 4 4 0 Thioredoxin Thioredoxin_4 PF13462.1 EGC29604.1 - 1.2 9.1 6.8 25 4.8 1.4 3.4 3 2 0 3 3 3 0 Thioredoxin M16C_assoc PF08367.6 EGC29605.1 - 6e-60 202.1 2.4 6e-60 202.1 1.7 2.0 3 0 0 3 3 3 1 Peptidase M16C associated Peptidase_M16_C PF05193.16 EGC29605.1 - 6.9e-27 94.2 0.4 8.2e-15 54.9 0.1 2.9 2 0 0 2 2 2 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC29605.1 - 3.6e-08 33.2 1.3 8.5e-08 32.0 0.0 2.3 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) TraC_F_IV PF11130.3 EGC29605.1 - 0.02 14.3 0.0 7.1 5.9 0.0 2.6 2 0 0 2 2 2 0 F pilus assembly Type-IV secretion system for plasmid transfer Mucin PF01456.12 EGC29607.1 - 2.3 7.9 14.2 1.8 8.3 1.1 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3053 PF11254.3 EGC29608.1 - 0.023 13.9 0.0 0.031 13.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Crystall_3 PF08964.5 EGC29608.1 - 0.049 13.3 0.3 0.072 12.8 0.2 1.3 1 0 0 1 1 1 0 Beta/Gamma crystallin DUF3053 PF11254.3 EGC29609.1 - 0.014 14.6 0.0 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) Crystall_3 PF08964.5 EGC29609.1 - 0.046 13.4 0.3 0.064 12.9 0.2 1.2 1 0 0 1 1 1 0 Beta/Gamma crystallin BUD22 PF09073.5 EGC29610.1 - 0.7 8.9 15.6 0.54 9.2 4.7 2.7 2 1 0 2 2 2 0 BUD22 TMEM154 PF15102.1 EGC29612.1 - 0.00012 21.8 0.4 0.02 14.5 0.1 2.6 2 0 0 2 2 2 1 TMEM154 protein family EphA2_TM PF14575.1 EGC29612.1 - 0.0026 18.1 0.4 1.4 9.3 0.0 2.7 2 0 0 2 2 2 2 Ephrin type-A receptor 2 transmembrane domain Tetraspannin PF00335.15 EGC29612.1 - 0.014 14.6 4.3 1.1 8.5 0.0 2.9 2 1 0 2 2 2 0 Tetraspanin family DUF4064 PF13273.1 EGC29612.1 - 0.14 12.3 4.4 0.44 10.6 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) GRP PF07172.6 EGC29612.1 - 0.14 12.6 0.2 6.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Glycine rich protein family DUF4446 PF14584.1 EGC29612.1 - 0.17 11.6 3.3 5.4 6.8 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF1628 PF07790.6 EGC29612.1 - 0.5 11.1 0.1 0.5 11.1 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1628) DUF1510 PF07423.6 EGC29612.1 - 0.53 9.6 9.9 0.86 8.9 0.8 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1510) DUF3377 PF11857.3 EGC29612.1 - 5.4 6.7 5.6 2.2 7.9 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) Hep_core_N PF08290.6 EGC29613.1 - 0.026 13.9 0.8 0.056 12.8 0.5 1.5 1 0 0 1 1 1 0 Hepatitis core protein, putative zinc finger GCD14 PF08704.5 EGC29614.1 - 0.38 10.2 15.4 0.15 11.5 0.7 3.1 3 0 0 3 3 3 0 tRNA methyltransferase complex GCD14 subunit ApbA_C PF08546.6 EGC29615.1 - 0.096 12.6 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA C terminal Beta-lactamase PF00144.19 EGC29616.1 - 5e-37 127.6 0.0 6.5e-37 127.2 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGC29616.1 - 0.011 14.9 0.0 0.12 11.5 0.0 2.1 2 0 0 2 2 2 0 D-alanyl-D-alanine carboxypeptidase MaoC_dehydratas PF01575.14 EGC29617.1 - 2e-22 78.8 0.0 2.2e-22 78.7 0.0 1.0 1 0 0 1 1 1 1 MaoC like domain MaoC_dehydrat_N PF13452.1 EGC29617.1 - 7.2e-05 22.5 0.0 9.8e-05 22.1 0.0 1.2 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase TIG PF01833.19 EGC29618.1 - 2.3e-15 56.3 19.0 3.3e-05 23.8 0.2 4.8 4 0 0 4 4 4 3 IPT/TIG domain LRR_8 PF13855.1 EGC29618.1 - 2.1e-11 43.3 29.1 0.00077 19.1 3.3 5.4 4 1 1 5 5 5 4 Leucine rich repeat LRR_4 PF12799.2 EGC29618.1 - 5e-05 22.8 37.1 0.0076 15.8 1.9 6.0 3 1 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC29618.1 - 0.0016 18.1 33.3 2.5 8.4 0.2 9.5 8 1 0 8 8 8 4 Leucine Rich Repeat LRR_7 PF13504.1 EGC29618.1 - 0.063 13.4 16.6 9.8 6.8 0.1 7.7 7 0 0 7 7 7 0 Leucine rich repeat LRR_6 PF13516.1 EGC29618.1 - 1.4 9.1 36.8 2.6 8.3 0.0 8.9 9 0 0 9 9 9 0 Leucine Rich repeat ketoacyl-synt PF00109.21 EGC29619.1 - 7.3e-47 159.9 0.0 9.6e-47 159.5 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC29619.1 - 2.3e-25 88.7 0.0 4.6e-25 87.7 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGC29619.1 - 0.0021 17.0 0.0 0.004 16.1 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain VKG_Carbox PF05090.9 EGC29620.1 - 1.8e-07 30.4 23.2 1.8e-07 30.3 15.3 1.5 1 1 0 1 1 1 1 Vitamin K-dependent gamma-carboxylase TPR_8 PF13181.1 EGC29620.1 - 0.001 18.7 2.1 0.012 15.2 0.4 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC29620.1 - 0.021 14.4 0.1 1.1 8.9 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_2 PF07719.12 EGC29620.1 - 0.036 13.9 0.1 0.16 11.9 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC29620.1 - 0.098 12.6 0.1 0.26 11.2 0.0 1.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Ank_2 PF12796.2 EGC29622.1 - 1.7e-05 25.0 0.0 0.013 15.7 0.0 1.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) p450 PF00067.17 EGC29624.1 - 6.3e-86 288.7 0.0 7.3e-86 288.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 MFS_1 PF07690.11 EGC29625.1 - 5.9e-23 81.1 18.6 1.4e-19 70.0 8.0 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily Nuc_H_symport PF03825.11 EGC29625.1 - 1.3e-08 34.0 32.6 7.5e-05 21.6 6.9 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter MFS_1_like PF12832.2 EGC29625.1 - 0.00012 21.8 3.7 0.00012 21.8 2.6 2.9 4 0 0 4 4 4 1 MFS_1 like family Tmemb_9 PF05434.6 EGC29625.1 - 0.013 15.3 0.4 4.7 6.9 0.0 2.6 2 0 0 2 2 2 0 TMEM9 MFS_3 PF05977.8 EGC29625.1 - 0.014 13.5 0.0 0.023 12.8 0.0 1.3 1 0 0 1 1 1 0 Transmembrane secretion effector PIG-P PF08510.7 EGC29625.1 - 0.13 11.8 0.1 0.13 11.8 0.0 3.5 4 1 0 4 4 4 0 PIG-P ADH_zinc_N_2 PF13602.1 EGC29626.1 - 5.4e-14 53.1 0.0 8.6e-14 52.5 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC29626.1 - 1.5e-12 47.1 0.0 2.5e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC29626.1 - 5.9e-06 25.8 0.0 1.9e-05 24.1 0.0 1.8 1 1 1 2 2 2 1 Zinc-binding dehydrogenase Semialdhyde_dh PF01118.19 EGC29626.1 - 0.0035 17.6 0.0 0.0061 16.8 0.0 1.5 1 1 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain ACOX PF01756.14 EGC29627.1 - 4.9e-16 58.6 0.0 8.7e-16 57.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGC29627.1 - 6.1e-12 44.8 0.1 1.3e-11 43.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_ox_N PF14749.1 EGC29627.1 - 2.5e-10 40.7 0.0 4.6e-10 39.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_1 PF00441.19 EGC29627.1 - 7.3e-07 29.3 0.0 1.8e-06 28.0 0.0 1.7 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Myotub-related PF06602.9 EGC29628.1 - 5.6e-124 413.4 2.4 1.8e-123 411.8 1.7 1.8 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain PX PF00787.19 EGC29628.1 - 6.6e-16 58.1 4.5 9.8e-16 57.5 1.6 2.4 2 0 0 2 2 2 1 PX domain PH PF00169.24 EGC29628.1 - 2.7e-08 33.9 1.7 2.7e-08 33.9 1.2 3.1 2 1 0 2 2 2 1 PH domain GRAM PF02893.15 EGC29628.1 - 0.00023 20.5 0.1 0.00076 18.9 0.1 1.9 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 EGC29628.1 - 0.0022 18.2 0.0 0.0093 16.2 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family OTU PF02338.14 EGC29630.1 - 3.3e-14 53.4 0.2 4.5e-14 53.0 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Oxysterol_BP PF01237.13 EGC29631.1 - 7.6e-65 218.7 5.9 1e-64 218.3 4.1 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein BLVR PF06375.6 EGC29631.1 - 0.049 13.4 14.7 0.019 14.7 3.8 2.2 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) DUF4419 PF14388.1 EGC29632.1 - 5.3e-92 308.2 2.5 6.6e-92 307.9 1.7 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) CH PF00307.26 EGC29633.1 - 1.3e-12 47.6 0.2 3e-12 46.5 0.1 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain EB1 PF03271.12 EGC29633.1 - 2.1e-10 40.4 0.6 2.1e-10 40.4 0.4 2.6 2 1 1 3 3 3 1 EB1-like C-terminal motif CAMSAP_CH PF11971.3 EGC29633.1 - 0.0018 17.8 0.0 0.0043 16.6 0.0 1.6 1 0 0 1 1 1 1 CAMSAP CH domain NPV_P10 PF05531.7 EGC29633.1 - 0.074 13.3 0.1 0.074 13.3 0.1 2.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein Cofilin_ADF PF00241.15 EGC29634.1 - 1.8e-07 31.1 2.3 2.6e-06 27.3 0.0 3.5 2 1 1 4 4 4 1 Cofilin/tropomyosin-type actin-binding protein DUF3677 PF12432.3 EGC29634.1 - 0.83 10.1 5.7 1.7 9.1 0.7 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3677) FMN_red PF03358.10 EGC29635.1 - 1.2e-28 99.5 0.0 1.8e-28 99.0 0.0 1.2 1 0 0 1 1 1 1 NADPH-dependent FMN reductase Flavodoxin_2 PF02525.12 EGC29635.1 - 8.5e-05 22.1 0.0 0.00012 21.6 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin-like fold Dicty_CAR PF05462.6 EGC29636.1 - 3.5e-12 45.8 19.6 6.5e-12 44.9 13.6 1.4 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EGC29636.1 - 1.1e-09 37.7 16.3 1.1e-08 34.5 11.3 2.1 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 EGC29636.1 - 9.3e-09 34.7 13.9 9.3e-09 34.7 9.7 1.7 2 0 0 2 2 2 1 7 transmembrane receptor (rhodopsin family) Ocular_alb PF02101.10 EGC29636.1 - 0.00031 19.4 7.9 0.00043 19.0 5.5 1.3 1 0 0 1 1 1 1 Ocular albinism type 1 protein Col_cuticle_N PF01484.12 EGC29636.1 - 0.1 12.2 0.2 0.1 12.2 0.1 2.8 3 0 0 3 3 3 0 Nematode cuticle collagen N-terminal domain DUF4231 PF14015.1 EGC29636.1 - 6.3 6.8 7.4 1.3 8.9 0.1 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) DUF4131 PF13567.1 EGC29636.1 - 9.6 5.5 11.3 1.8 7.9 1.0 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) UNC-93 PF05978.11 EGC29637.1 - 1e-14 54.3 8.2 1e-14 54.3 5.7 3.0 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 MFS_1 PF07690.11 EGC29637.1 - 1.8e-14 53.2 28.6 1.8e-14 53.2 19.8 1.8 1 1 0 1 1 1 1 Major Facilitator Superfamily TIG PF01833.19 EGC29638.1 - 3.7e-05 23.6 4.4 3.7e-05 23.6 3.1 5.1 4 1 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.8 EGC29638.1 - 0.011 15.8 10.7 0.011 15.8 7.4 2.8 2 0 0 2 2 2 0 EGF-like domain SKG6 PF08693.5 EGC29638.1 - 0.012 14.9 8.2 0.032 13.5 5.7 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF4448 PF14610.1 EGC29638.1 - 0.015 14.8 1.7 0.015 14.8 1.2 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) DUF1191 PF06697.7 EGC29638.1 - 0.039 12.7 0.5 0.063 12.0 0.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) LRR19-TM PF15176.1 EGC29638.1 - 0.042 13.5 1.3 0.094 12.4 0.9 1.6 1 0 0 1 1 1 0 Leucine-rich repeat family 19 TM domain DUF3827 PF12877.2 EGC29638.1 - 0.49 8.4 9.7 0.085 10.9 4.2 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3827) DUF3377 PF11857.3 EGC29638.1 - 0.72 9.5 5.0 1.7 8.3 3.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4519 PF15012.1 EGC29638.1 - 2.7 7.9 8.2 8.4 6.3 5.7 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) HECT PF00632.20 EGC29639.1 - 3.2e-74 249.9 2.3 3.2e-74 249.9 1.6 2.4 2 0 0 2 2 2 1 HECT-domain (ubiquitin-transferase) Filamin PF00630.14 EGC29639.1 - 3e-18 66.2 9.3 1.4e-11 44.8 0.3 3.8 3 0 0 3 3 3 2 Filamin/ABP280 repeat YbaJ PF10757.4 EGC29640.1 - 0.042 13.9 0.0 0.064 13.3 0.0 1.3 1 0 0 1 1 1 0 Biofilm formation regulator YbaJ TIR-like PF10137.4 EGC29641.1 - 4.1e-05 23.1 0.4 0.00011 21.8 0.3 1.8 1 1 0 1 1 1 1 Predicted nucleotide-binding protein containing TIR-like domain Nefa_Nip30_N PF10187.4 EGC29641.1 - 0.17 12.0 1.4 0.32 11.1 0.2 2.0 2 0 0 2 2 2 0 N-terminal domain of NEFA-interacting nuclear protein NIP30 Fer4_17 PF13534.1 EGC29645.1 - 0.0053 17.0 1.3 0.0053 17.0 0.9 3.0 3 0 0 3 3 3 1 4Fe-4S dicluster domain BPL_LplA_LipB PF03099.14 EGC29646.1 - 0.028 14.4 0.2 0.6 10.1 0.0 2.2 2 0 0 2 2 2 0 Biotin/lipoate A/B protein ligase family XisI PF08869.6 EGC29646.1 - 0.064 13.3 0.7 0.064 13.3 0.5 1.9 2 1 1 3 3 3 0 XisI protein DUF342 PF03961.8 EGC29646.1 - 0.22 9.9 2.4 0.26 9.6 1.7 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF342) ER PF01133.12 EGC29646.1 - 0.42 10.3 5.4 0.92 9.2 0.5 2.3 1 1 1 2 2 2 0 Enhancer of rudimentary Cor1 PF04803.7 EGC29646.1 - 1.3 8.7 6.4 0.71 9.6 1.8 2.0 1 1 1 2 2 2 0 Cor1/Xlr/Xmr conserved region RNB PF00773.14 EGC29647.1 - 3.9e-89 299.1 0.0 3.9e-89 299.1 0.0 3.5 3 1 0 3 3 3 2 RNB domain DUF4248 PF14053.1 EGC29648.1 - 0.13 11.8 4.6 0.45 10.1 3.2 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) V_ATPase_I PF01496.14 EGC29648.1 - 0.25 9.1 8.1 0.39 8.5 5.6 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family PBP1_TM PF14812.1 EGC29648.1 - 0.3 11.4 3.3 0.74 10.1 2.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Glyco_hydro_77 PF02446.12 EGC29649.1 - 0.011 14.3 1.7 0.012 14.1 1.1 1.0 1 0 0 1 1 1 0 4-alpha-glucanotransferase ALIX_LYPXL_bnd PF13949.1 EGC29649.1 - 0.12 11.3 8.5 0.15 11.0 5.9 1.2 1 0 0 1 1 1 0 ALIX V-shaped domain binding to HIV MecA_N PF05223.6 EGC29649.1 - 0.64 10.0 5.5 0.26 11.3 1.8 1.7 2 0 0 2 2 2 0 NTF2-like N-terminal transpeptidase domain DUF2660 PF10859.3 EGC29649.1 - 1.8 8.8 8.1 0.79 9.9 3.6 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2660) Lipl32 PF12103.3 EGC29649.1 - 3.6 7.0 8.4 0.28 10.6 1.9 1.8 1 1 1 2 2 2 0 Surface lipoprotein of Spirochaetales order SRR PF07709.6 EGC29652.1 - 0.03 14.4 0.2 0.065 13.4 0.0 1.7 2 0 0 2 2 2 0 Seven Residue Repeat Tim44 PF04280.10 EGC29654.1 - 1.6e-07 31.3 0.2 9.2e-07 28.9 0.2 2.0 1 1 0 1 1 1 1 Tim44-like domain DEAD_2 PF06733.10 EGC29655.1 - 2e-44 151.0 0.2 3.4e-44 150.2 0.1 1.4 1 0 0 1 1 1 1 DEAD_2 Helicase_C_2 PF13307.1 EGC29655.1 - 6.8e-30 104.2 0.0 1.7e-29 102.9 0.0 1.7 1 0 0 1 1 1 1 Helicase C-terminal domain ResIII PF04851.10 EGC29655.1 - 7.2e-08 32.4 0.4 2.4e-07 30.7 0.0 2.1 2 1 0 2 2 2 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGC29655.1 - 5.2e-06 26.0 0.0 0.00021 20.8 0.0 2.5 1 1 0 1 1 1 1 DEAD/DEAH box helicase AAA_11 PF13086.1 EGC29655.1 - 6.4e-06 25.9 0.0 1.4e-05 24.7 0.0 1.5 1 0 0 1 1 1 1 AAA domain SNF2_N PF00176.18 EGC29655.1 - 0.00022 20.1 0.1 0.00077 18.3 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain PhoH PF02562.11 EGC29655.1 - 0.0053 16.0 0.0 0.92 8.6 0.0 2.3 2 0 0 2 2 2 2 PhoH-like protein AAA_19 PF13245.1 EGC29655.1 - 0.013 15.1 0.0 0.032 13.9 0.0 1.6 1 1 0 1 1 1 0 Part of AAA domain Laminin_EGF PF00053.19 EGC29656.1 - 0.0043 16.9 21.2 0.028 14.3 2.5 2.7 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC29656.1 - 0.005 16.9 38.0 0.022 14.9 12.5 2.9 2 0 0 2 2 2 2 EGF-like domain Coiled PF05710.7 EGC29657.1 - 1.1 9.7 6.3 1.1 9.7 4.3 1.1 1 0 0 1 1 1 0 Coiled coil zf-RING_2 PF13639.1 EGC29658.1 - 5.3e-13 48.5 3.5 5.3e-13 48.5 2.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29658.1 - 1.7e-07 30.7 1.7 2.9e-07 30.0 1.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29658.1 - 1.8e-07 31.0 4.4 3.9e-07 29.9 3.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29658.1 - 5.1e-07 29.3 3.1 5.1e-07 29.3 2.2 2.3 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC29658.1 - 5.1e-07 29.2 3.3 1.2e-06 28.1 2.3 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29658.1 - 7.3e-06 26.0 3.4 7.3e-06 26.0 2.3 4.1 3 3 0 3 3 3 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGC29658.1 - 0.02 14.6 2.1 0.02 14.6 1.4 3.9 3 3 2 5 5 5 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC29658.1 - 1.2 8.8 4.6 2.8 7.5 3.1 1.7 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF1162 PF06650.7 EGC29659.1 - 8.7e-39 133.3 10.3 8.7e-39 133.3 7.2 4.8 5 1 0 5 5 5 1 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGC29659.1 - 1.5e-27 95.4 2.5 1.5e-27 95.4 1.7 3.9 4 0 0 4 4 4 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC29659.1 - 8.7e-07 29.0 0.0 4.1e-06 26.8 0.0 2.1 2 0 0 2 2 2 1 ATG C terminal domain Atrophin-1 PF03154.10 EGC29659.1 - 0.0053 14.9 0.6 0.013 13.7 0.4 1.6 1 0 0 1 1 1 1 Atrophin-1 family Pkinase PF00069.20 EGC29660.1 - 9.6e-67 224.8 0.0 1.1e-66 224.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29660.1 - 1e-34 119.8 0.0 1.8e-34 119.0 0.0 1.3 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC29660.1 - 0.00092 18.2 0.0 0.01 14.8 0.0 2.1 2 0 0 2 2 2 1 Kinase-like Pox_ser-thr_kin PF05445.6 EGC29660.1 - 0.011 14.5 0.1 0.41 9.3 0.0 2.2 2 0 0 2 2 2 0 Poxvirus serine/threonine protein kinase HEAT PF02985.17 EGC29661.1 - 2.6e-07 30.1 4.6 2.3 8.5 0.0 5.6 5 0 0 5 5 5 4 HEAT repeat HEAT_2 PF13646.1 EGC29661.1 - 5.7e-06 26.5 0.2 0.00074 19.7 0.1 3.2 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGC29661.1 - 0.18 12.3 0.5 2.5 8.6 0.2 2.9 3 0 0 3 3 3 0 HEAT-like repeat Metallophos PF00149.23 EGC29662.1 - 9.5e-08 31.6 0.1 1.9e-07 30.6 0.1 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC29662.1 - 0.0028 17.5 0.0 0.021 14.6 0.0 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain NIF PF03031.13 EGC29663.1 - 3.9e-52 176.1 3.4 3.9e-52 176.1 2.4 1.7 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Tetraspannin PF00335.15 EGC29663.1 - 6.3 6.0 9.2 8.6 5.5 6.2 1.5 1 1 0 1 1 1 0 Tetraspanin family OTU PF02338.14 EGC29667.1 - 3.3e-14 53.5 0.2 4.4e-14 53.1 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease IlvGEDA_leader PF08046.6 EGC29668.1 - 3.2 6.9 6.5 4.2 6.5 4.5 1.1 1 0 0 1 1 1 0 IlvGEDA operon leader peptide HTH_29 PF13551.1 EGC29671.1 - 4.1e-10 39.8 0.0 4.9e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EGC29671.1 - 2.3e-07 30.2 0.2 1.2e-05 24.7 0.0 2.6 3 0 0 3 3 3 1 Homeodomain-like domain HTH_32 PF13565.1 EGC29671.1 - 6.4e-06 26.8 0.0 1.3e-05 25.9 0.0 1.5 1 1 0 1 1 1 1 Homeodomain-like domain HTH_38 PF13936.1 EGC29671.1 - 1.1e-05 24.8 4.8 1.7e-05 24.2 0.4 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_33 PF13592.1 EGC29671.1 - 2.2e-05 23.9 0.4 0.00018 20.9 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_Tnp_Tc3_2 PF01498.13 EGC29671.1 - 7e-05 22.8 0.6 0.23 11.5 0.0 2.4 2 1 0 2 2 2 2 Transposase HTH_28 PF13518.1 EGC29671.1 - 0.00041 20.2 0.2 0.01 15.7 0.0 2.4 2 1 0 2 2 2 1 Helix-turn-helix domain Sigma70_r4_2 PF08281.7 EGC29671.1 - 0.0014 18.0 0.5 0.007 15.8 0.0 2.2 2 0 0 2 2 2 1 Sigma-70, region 4 HTH_7 PF02796.10 EGC29671.1 - 0.0033 17.2 1.0 0.039 13.8 0.0 2.6 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Apc15p PF05841.6 EGC29673.1 - 3.9 8.2 10.5 2.8 8.7 3.1 2.5 2 1 0 2 2 2 0 Apc15p protein Spo12 PF05032.7 EGC29674.1 - 0.11 12.1 0.8 0.22 11.1 0.6 1.5 1 0 0 1 1 1 0 Spo12 family zf-RING_2 PF13639.1 EGC29676.1 - 9.3e-12 44.5 7.3 1.6e-11 43.8 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29676.1 - 1.1e-08 34.6 5.7 1.7e-08 34.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29676.1 - 3.9e-08 32.8 10.8 7.9e-08 31.8 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29676.1 - 1.2e-07 31.7 6.2 3.2e-07 30.3 4.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC29676.1 - 3.5e-07 30.1 10.0 5.9e-07 29.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29676.1 - 6.4e-07 28.9 8.9 1.2e-06 28.1 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29676.1 - 0.00035 20.3 9.3 0.00082 19.2 6.0 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC29676.1 - 0.0012 18.3 11.2 0.0022 17.5 7.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC29676.1 - 0.0032 17.1 1.6 0.0032 17.1 1.1 3.0 2 1 1 3 3 3 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGC29676.1 - 0.0051 16.6 2.0 0.013 15.3 1.4 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGC29676.1 - 0.02 14.4 4.4 0.059 12.9 3.1 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CAF-1_p150 PF11600.3 EGC29676.1 - 0.16 11.2 64.6 0.016 14.6 27.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1272 PF06906.6 EGC29676.1 - 1.4 8.7 7.9 2.9 7.8 5.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) RRM_1 PF00076.17 EGC29677.1 - 1e-21 76.3 0.0 1.4e-21 75.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC29677.1 - 6.8e-16 58.0 0.0 1e-15 57.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC29677.1 - 2.9e-08 33.4 0.0 5.8e-08 32.4 0.0 1.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UreE_C PF05194.7 EGC29677.1 - 0.026 14.6 6.1 0.055 13.5 4.3 1.5 1 0 0 1 1 1 0 UreE urease accessory protein, C-terminal domain GATA PF00320.22 EGC29678.1 - 1.4e-07 30.7 8.8 2.3e-07 30.0 6.1 1.3 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.22 EGC29679.1 - 0.00041 19.6 1.9 0.00091 18.5 1.3 1.6 1 0 0 1 1 1 1 GATA zinc finger TerY-C PF15616.1 EGC29679.1 - 0.011 15.7 3.3 0.02 14.8 2.3 1.4 1 0 0 1 1 1 0 TerY-C metal binding domain BBP1_N PF15271.1 EGC29680.1 - 0.54 10.6 7.3 0.56 10.5 5.0 1.0 1 0 0 1 1 1 0 Spindle pole body component BBP1, Mps2-binding protein Secretin_N_2 PF07655.8 EGC29680.1 - 1 9.8 13.3 1.2 9.5 9.2 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain Macoilin PF09726.4 EGC29680.1 - 3.4 5.8 5.9 3.3 5.8 4.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF912 PF06024.7 EGC29680.1 - 5.4 7.1 6.4 6.2 6.9 4.4 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Inhibitor_I71 PF12628.2 EGC29681.1 - 0.016 14.8 0.6 0.019 14.6 0.4 1.1 1 0 0 1 1 1 0 Falstatin, cysteine peptidase inhibitor GATA PF00320.22 EGC29682.1 - 4.7e-05 22.6 0.5 5.6e-05 22.3 0.4 1.2 1 0 0 1 1 1 1 GATA zinc finger Paired_CXXCH_1 PF09699.5 EGC29682.1 - 0.0093 15.4 0.1 0.01 15.3 0.0 1.2 1 0 0 1 1 1 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C554 PF13435.1 EGC29682.1 - 0.051 13.6 0.1 0.052 13.5 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c554 and c-prime Cytochrome_C7 PF14522.1 EGC29682.1 - 0.055 13.1 0.2 0.056 13.0 0.1 1.1 1 0 0 1 1 1 0 Cytochrome c7 GATA PF00320.22 EGC29684.1 - 3.3e-12 45.5 5.9 3.3e-12 45.5 4.1 2.0 2 0 0 2 2 2 1 GATA zinc finger DZR PF12773.2 EGC29684.1 - 0.061 13.1 3.9 1 9.2 2.3 2.4 2 1 0 2 2 2 0 Double zinc ribbon Secretin_N_2 PF07655.8 EGC29686.1 - 5.4 7.4 9.7 6.4 7.2 6.7 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Pkip-1 PF06878.6 EGC29688.1 - 0.05 13.4 0.2 8.7 6.1 0.0 2.1 2 0 0 2 2 2 0 Pkip-1 protein YjcQ PF09639.5 EGC29688.1 - 0.075 13.1 0.1 1.1 9.3 0.0 2.3 2 0 0 2 2 2 0 YjcQ protein MukB PF04310.7 EGC29688.1 - 0.098 11.9 0.1 0.18 11.1 0.1 1.4 1 1 0 1 1 1 0 MukB N-terminal RNase_T PF00929.19 EGC29690.1 - 3.9e-05 23.9 0.0 0.0001 22.6 0.0 1.7 1 0 0 1 1 1 1 Exonuclease MAM33 PF02330.11 EGC29690.1 - 0.018 14.7 2.4 1.5 8.5 0.2 2.9 3 0 0 3 3 3 0 Mitochondrial glycoprotein Asp-B-Hydro_N PF05279.6 EGC29691.1 - 2.7 7.7 7.7 1.6 8.5 3.8 1.5 1 1 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region DUF202 PF02656.10 EGC29692.1 - 1.8e-08 34.4 6.5 1.8e-08 34.4 4.5 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF202) Tmemb_cc2 PF10267.4 EGC29692.1 - 0.48 8.9 3.2 0.81 8.2 2.2 1.3 1 0 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein DUF2207 PF09972.4 EGC29692.1 - 4.9 5.6 6.3 9.9 4.6 4.2 1.6 1 1 0 1 1 1 0 Predicted membrane protein (DUF2207) Phospholip_B PF04916.8 EGC29693.1 - 4.3e-133 444.3 12.5 5.6e-133 443.9 8.7 1.0 1 0 0 1 1 1 1 Phospholipase B Exo_endo_phos PF03372.18 EGC29694.1 - 1.1e-20 74.6 0.0 1.3e-20 74.4 0.0 1.0 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGC29694.1 - 3.9e-11 42.6 0.0 5.6e-11 42.1 0.0 1.2 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase SapB_1 PF05184.10 EGC29695.1 - 6.4e-14 51.3 2.6 2.1e-10 40.1 0.5 3.5 2 1 0 2 2 2 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC29695.1 - 6.6e-14 51.6 0.7 2.5e-06 27.3 0.1 2.6 2 0 0 2 2 2 2 Saposin-like type B, region 2 Rubredoxin PF00301.15 EGC29695.1 - 0.026 14.3 5.6 2.7 7.9 0.9 3.4 3 1 0 3 3 3 0 Rubredoxin Yippee-Mis18 PF03226.9 EGC29695.1 - 0.073 13.1 2.7 0.4 10.7 1.9 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly GBP PF02263.14 EGC29696.1 - 0.0034 16.4 0.2 0.0085 15.1 0.0 1.8 2 0 0 2 2 2 1 Guanylate-binding protein, N-terminal domain SAC3_GANP PF03399.11 EGC29697.1 - 1.6e-44 151.9 5.9 1.9e-44 151.7 4.1 1.1 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI_Csn8 PF10075.4 EGC29697.1 - 0.0058 16.4 3.7 0.014 15.1 2.6 1.7 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 RasGEF PF00617.14 EGC29698.1 - 2.9e-54 183.6 0.9 7.3e-54 182.3 0.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC29698.1 - 2.4e-12 46.8 0.8 2.4e-12 46.8 0.5 2.2 2 0 0 2 2 2 1 RasGEF N-terminal motif FtsZ_C PF12327.3 EGC29699.1 - 7.4e-31 106.0 0.6 2e-30 104.7 0.4 1.8 1 0 0 1 1 1 1 FtsZ family, C-terminal domain Tubulin PF00091.20 EGC29699.1 - 7.7e-28 97.7 4.3 7.7e-28 97.7 3.0 2.6 2 2 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain Med15 PF09606.5 EGC29699.1 - 0.0037 15.5 48.5 0.0044 15.2 33.6 1.1 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal PAT1 PF09770.4 EGC29699.1 - 1.2 7.2 53.0 1.7 6.7 36.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FKBP_N PF01346.13 EGC29699.1 - 2.3 8.2 18.4 0.11 12.5 1.0 2.5 2 0 0 2 2 2 0 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase AMP-binding PF00501.23 EGC29700.1 - 2.4e-93 312.7 0.0 3e-93 312.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC29700.1 - 4.3e-16 59.6 0.0 1.1e-15 58.3 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain DUF1322 PF07032.6 EGC29700.1 - 0.021 15.0 0.2 0.048 13.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1322) Solute_trans_a PF03619.11 EGC29701.1 - 6.1e-85 284.8 27.0 6.1e-85 284.8 18.7 1.4 2 0 0 2 2 2 1 Organic solute transporter Ostalpha Fumarate_red_D PF02313.12 EGC29701.1 - 4.4 7.2 9.4 15 5.5 1.5 3.0 2 1 1 3 3 3 0 Fumarate reductase subunit D Ninjurin PF04923.7 EGC29701.1 - 8.7 6.1 11.3 7.7 6.3 0.4 3.2 2 1 1 3 3 3 0 Ninjurin Cyt-b5 PF00173.23 EGC29703.1 - 8.4e-21 73.5 0.1 1.1e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Thioredoxin PF00085.15 EGC29704.1 - 6.4e-67 221.7 3.9 5.7e-33 112.6 0.3 2.4 2 0 0 2 2 2 2 Thioredoxin ERp29 PF07749.7 EGC29704.1 - 3.9e-27 94.7 1.8 9.1e-27 93.5 1.3 1.7 1 0 0 1 1 1 1 Endoplasmic reticulum protein ERp29, C-terminal domain Thioredoxin_2 PF13098.1 EGC29704.1 - 1.7e-20 73.3 2.5 2.8e-09 37.1 0.1 3.0 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC29704.1 - 3.2e-15 56.0 2.3 9.1e-07 28.9 0.2 4.3 2 2 1 3 3 3 2 Thioredoxin-like Thioredoxin_7 PF13899.1 EGC29704.1 - 2.6e-12 46.5 0.4 3.3e-06 27.0 0.1 2.5 2 0 0 2 2 2 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EGC29704.1 - 1e-09 38.4 3.8 0.00048 19.9 0.2 3.5 1 1 2 3 3 3 2 Thioredoxin-like domain AhpC-TSA PF00578.16 EGC29704.1 - 1.4e-09 37.6 1.3 3.9e-05 23.3 0.1 2.4 2 0 0 2 2 2 2 AhpC/TSA family ERp29_N PF07912.8 EGC29704.1 - 1.9e-09 37.5 1.7 0.0015 18.4 0.1 2.6 2 0 0 2 2 2 2 ERp29, N-terminal domain Redoxin PF08534.5 EGC29704.1 - 1.8e-07 30.7 5.2 0.0033 16.9 0.1 2.7 2 1 0 2 2 2 2 Redoxin DDE_Tnp_1_2 PF13586.1 EGC29704.1 - 0.0019 18.3 0.0 9.7 6.4 0.0 3.4 2 1 1 3 3 3 0 Transposase DDE domain UL11 PF11094.3 EGC29704.1 - 0.0064 16.2 0.6 0.29 10.9 0.0 2.5 2 0 0 2 2 2 1 Membrane-associated tegument protein Thioredoxin_4 PF13462.1 EGC29704.1 - 0.022 14.7 6.9 0.17 11.8 0.4 3.4 2 2 1 3 3 3 0 Thioredoxin Utp13 PF08625.6 EGC29704.1 - 0.034 13.7 0.0 0.13 11.9 0.0 1.8 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain Mu-like_Com PF10122.4 EGC29704.1 - 0.054 12.5 1.6 7.7 5.6 0.1 2.6 2 0 0 2 2 2 0 Mu-like prophage protein Com BAG PF02179.11 EGC29704.1 - 0.099 12.7 0.1 0.27 11.3 0.1 1.7 1 0 0 1 1 1 0 BAG domain Propeptide_C1 PF08127.8 EGC29704.1 - 0.32 10.6 2.6 12 5.6 0.1 2.6 2 0 0 2 2 2 0 Peptidase family C1 propeptide Pkinase PF00069.20 EGC29705.1 - 2.5e-47 161.1 15.5 4.5e-23 81.7 0.2 4.5 5 0 0 5 5 5 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29705.1 - 4.8e-25 88.1 0.3 1.7e-12 46.9 0.0 3.8 3 0 0 3 3 3 3 Protein tyrosine kinase RWD PF05773.17 EGC29705.1 - 2.2e-17 62.9 0.5 2.2e-17 62.9 0.4 3.2 3 0 0 3 3 3 1 RWD domain tRNA-synt_His PF13393.1 EGC29705.1 - 3.3e-13 49.3 0.0 2.5e-12 46.4 0.0 2.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 EGC29705.1 - 4.8e-09 35.7 0.1 4.8e-09 35.7 0.1 7.1 7 0 0 7 7 7 1 Anticodon binding domain of tRNAs HGTP_anticodon PF03129.15 EGC29705.1 - 5.8e-07 29.3 2.6 2.5e-06 27.3 0.1 3.2 3 0 0 3 3 3 1 Anticodon binding domain Trypsin_2 PF13365.1 EGC29706.1 - 0.0081 16.1 0.0 0.014 15.4 0.0 1.4 1 0 0 1 1 1 1 Trypsin-like peptidase domain IGR PF09597.5 EGC29707.1 - 6.4e-25 86.8 0.8 4.6e-24 84.0 0.0 2.3 2 0 0 2 2 2 1 IGR protein motif Ank_2 PF12796.2 EGC29708.1 - 7.2e-16 58.3 0.0 3.4e-15 56.1 0.0 2.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC29708.1 - 1.7e-15 55.9 0.0 3.8e-07 29.5 0.0 2.8 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGC29708.1 - 2.7e-15 56.0 0.1 2.5e-09 37.0 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC29708.1 - 1.8e-13 50.6 0.0 5.7e-13 48.9 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC29708.1 - 2e-09 36.7 0.0 0.00019 21.3 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Reo_sigmaC PF04582.7 EGC29709.1 - 3.2 6.8 8.4 3.2 6.8 1.2 2.2 1 1 0 2 2 2 0 Reovirus sigma C capsid protein zf-RING_2 PF13639.1 EGC29710.1 - 3.6e-09 36.3 7.7 3.6e-09 36.3 5.3 2.4 2 0 0 2 2 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29710.1 - 5e-09 35.6 4.9 5e-09 35.6 3.4 2.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29710.1 - 9.2e-09 35.1 10.4 9.2e-09 35.1 7.2 2.8 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29710.1 - 4.3e-08 32.6 10.7 4.3e-08 32.6 7.4 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC29710.1 - 4.6e-08 32.7 11.3 4.6e-08 32.7 7.9 2.6 2 0 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC29710.1 - 5.6e-08 32.3 8.6 5.6e-08 32.3 5.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC29710.1 - 5.1e-07 29.3 8.8 2e-06 27.4 4.6 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-B_box PF00643.19 EGC29710.1 - 6.9e-05 22.6 7.2 6.9e-05 22.6 5.0 3.0 3 1 0 3 3 3 1 B-box zinc finger U-box PF04564.10 EGC29710.1 - 0.001 19.0 0.1 0.011 15.6 0.0 2.4 2 0 0 2 2 2 1 U-box domain DUF4637 PF15470.1 EGC29710.1 - 0.29 10.7 2.9 0.62 9.6 2.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) DUF4503 PF14951.1 EGC29710.1 - 0.3 9.1 7.3 0.92 7.5 4.5 1.9 1 1 0 1 1 1 0 Domain of unknown function (DUF4503) zf-RING_6 PF14835.1 EGC29710.1 - 8.1 6.3 15.4 0.11 12.2 1.9 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein ketoacyl-synt PF00109.21 EGC29711.1 - 9.9e-64 215.2 0.0 2.2e-63 214.0 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC29711.1 - 7.9e-43 146.9 0.0 1.3e-42 146.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC29711.1 - 1.1e-30 105.9 0.0 3.3e-30 104.3 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC29711.1 - 1.2e-23 83.7 0.0 2.7e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC29711.1 - 1.7e-20 73.3 4.5 1.8e-20 73.2 0.0 3.4 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 EGC29711.1 - 1.8e-19 70.0 0.0 2.8e-19 69.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC29711.1 - 4.1e-16 59.3 0.0 7.5e-16 58.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC29711.1 - 1.4e-08 35.6 0.0 3.7e-08 34.3 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC29711.1 - 3.7e-07 29.8 0.1 8.2e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EGC29711.1 - 1.5e-06 28.3 0.1 4e-06 26.9 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EGC29711.1 - 1.8e-06 28.3 0.0 1.4e-05 25.4 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29711.1 - 1.4e-05 25.6 0.0 4.8e-05 23.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29711.1 - 1.9e-05 24.4 0.0 5.9e-05 22.8 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC29711.1 - 2.3e-05 23.5 0.0 4.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Peptidase_S28 PF05577.7 EGC29712.1 - 2.3e-79 267.0 0.3 3.3e-79 266.4 0.2 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 EGC29712.1 - 6e-06 25.9 0.0 1.2e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC29712.1 - 0.00029 20.7 0.0 0.00049 20.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC29712.1 - 0.00036 19.8 0.1 0.0015 17.7 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC29712.1 - 0.0045 16.7 0.0 0.0074 16.0 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 EGC29712.1 - 0.015 13.8 0.0 0.035 12.5 0.0 1.6 1 1 0 1 1 1 0 PS-10 peptidase S37 Ku_PK_bind PF08785.6 EGC29713.1 - 4.2e-42 142.8 2.7 4.2e-42 142.8 1.9 3.5 3 1 0 3 3 3 2 Ku C terminal domain like Ku_N PF03731.10 EGC29713.1 - 9.9e-30 103.6 4.3 2.3e-29 102.4 3.0 1.7 1 0 0 1 1 1 1 Ku70/Ku80 N-terminal alpha/beta domain Ku PF02735.11 EGC29713.1 - 1.1e-26 93.4 1.5 1.5e-26 93.0 0.0 2.0 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_C PF03730.9 EGC29713.1 - 1.7e-09 38.1 5.1 3.4e-09 37.0 1.9 2.8 2 0 0 2 2 2 1 Ku70/Ku80 C-terminal arm SBP_bac_5 PF00496.17 EGC29713.1 - 0.0047 15.8 0.1 0.01 14.6 0.0 1.5 1 0 0 1 1 1 1 Bacterial extracellular solute-binding proteins, family 5 Middle VWA PF00092.23 EGC29713.1 - 0.0056 16.4 2.0 0.0056 16.4 1.4 2.3 3 0 0 3 3 3 1 von Willebrand factor type A domain MGS PF02142.17 EGC29713.1 - 0.013 15.4 0.1 0.038 13.9 0.1 1.8 1 0 0 1 1 1 0 MGS-like domain TatD_DNase PF01026.16 EGC29715.1 - 8.6e-49 166.0 0.0 1.1e-48 165.6 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase EGF_2 PF07974.8 EGC29717.1 - 9e-07 28.9 32.2 0.00024 21.1 8.5 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC29717.1 - 0.0069 16.3 16.4 0.034 14.2 1.2 3.1 3 0 0 3 3 3 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC29717.1 - 0.048 13.6 21.6 0.48 10.3 5.2 2.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) DUF1673 PF07895.6 EGC29718.1 - 0.0017 17.9 7.7 0.0017 17.9 5.3 1.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1673) Scm3 PF10384.4 EGC29718.1 - 0.0039 16.6 0.4 0.0094 15.4 0.1 1.7 1 1 1 2 2 2 1 Centromere protein Scm3 DUF2207 PF09972.4 EGC29718.1 - 0.012 14.2 4.0 0.015 13.9 2.8 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) MIG-14_Wnt-bd PF06664.7 EGC29718.1 - 0.021 13.6 6.1 0.027 13.3 4.2 1.1 1 0 0 1 1 1 0 Wnt-binding factor required for Wnt secretion Spore_III_AE PF09546.5 EGC29718.1 - 0.035 13.0 1.7 0.04 12.8 1.2 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) IBV_3C PF03620.8 EGC29718.1 - 0.064 13.1 2.0 0.1 12.5 1.3 1.3 1 1 0 1 1 1 0 IBV 3C protein DUF788 PF05620.6 EGC29718.1 - 0.32 10.8 4.5 0.46 10.3 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) NPCC PF08058.6 EGC29718.1 - 0.43 10.4 3.4 0.16 11.8 0.5 1.6 2 1 0 2 2 2 0 Nuclear pore complex component CLU PF13236.1 EGC29719.1 - 5e-54 183.0 0.2 2e-53 181.0 0.0 2.2 2 0 0 2 2 2 1 Clustered mitochondria UQ_con PF00179.21 EGC29719.1 - 1.6e-28 98.9 0.0 8.3e-28 96.5 0.0 2.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme eIF3_p135 PF12807.2 EGC29719.1 - 3.1e-15 56.5 1.1 3.1e-15 56.5 0.8 5.9 4 3 0 5 5 5 1 Translation initiation factor eIF3 subunit 135 zf-CCCH PF00642.19 EGC29719.1 - 0.00027 20.5 1.0 0.00089 18.8 0.7 1.9 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Yip1 PF04893.12 EGC29720.1 - 4.7e-13 49.0 9.7 4.7e-13 49.0 6.7 1.7 1 1 1 2 2 2 2 Yip1 domain YIF1 PF03878.10 EGC29720.1 - 0.0065 15.6 7.0 0.011 14.9 4.8 1.3 1 0 0 1 1 1 1 YIF1 DUF1700 PF08006.6 EGC29720.1 - 4 6.6 12.0 2.1 7.5 6.5 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1700) Pkinase PF00069.20 EGC29721.1 - 1.9e-35 122.2 5.0 3.3e-18 65.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29721.1 - 6.3e-17 61.5 4.0 5.3e-09 35.5 0.2 2.7 3 0 0 3 3 3 2 Protein tyrosine kinase RabGAP-TBC PF00566.13 EGC29723.1 - 7.4e-05 22.3 0.0 7.4e-05 22.3 0.0 1.0 1 0 0 1 1 1 1 Rab-GTPase-TBC domain DNA_pol_A_exo1 PF01612.15 EGC29725.1 - 2.5e-22 79.2 0.9 4.7e-22 78.2 0.6 1.5 1 0 0 1 1 1 1 3'-5' exonuclease cobW PF02492.14 EGC29726.1 - 3.1e-48 163.5 0.2 5.2e-48 162.8 0.1 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGC29726.1 - 4.9e-17 61.4 0.0 7.5e-17 60.8 0.0 1.3 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain ATP_bind_1 PF03029.12 EGC29726.1 - 0.00031 20.3 0.6 0.011 15.3 0.0 2.5 2 1 0 2 2 2 1 Conserved hypothetical ATP binding protein Arch_ATPase PF01637.13 EGC29726.1 - 0.0026 17.5 0.8 0.006 16.2 0.0 2.0 2 0 0 2 2 2 1 Archaeal ATPase AAA_22 PF13401.1 EGC29726.1 - 0.0031 17.6 0.0 0.0099 16.0 0.0 1.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGC29726.1 - 0.0055 16.6 0.4 0.025 14.5 0.3 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase MobB PF03205.9 EGC29726.1 - 0.0093 15.6 0.0 0.031 13.9 0.0 1.9 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGC29726.1 - 0.018 13.9 1.2 0.03 13.2 0.8 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EGC29726.1 - 0.019 14.4 0.1 0.053 12.9 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_14 PF13173.1 EGC29726.1 - 0.019 14.8 0.1 0.087 12.7 0.1 2.3 1 1 0 1 1 1 0 AAA domain ArgK PF03308.11 EGC29726.1 - 0.022 13.5 0.4 0.88 8.2 0.0 2.7 3 0 0 3 3 3 0 ArgK protein AAA_18 PF13238.1 EGC29726.1 - 0.045 14.0 0.1 0.045 14.0 0.1 3.0 1 1 0 2 2 2 0 AAA domain Viral_helicase1 PF01443.13 EGC29726.1 - 0.053 13.0 0.3 0.26 10.7 0.0 2.3 3 1 0 3 3 3 0 Viral (Superfamily 1) RNA helicase AAA_29 PF13555.1 EGC29726.1 - 0.058 12.9 0.4 0.15 11.6 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Filo_VP35 PF02097.10 EGC29726.1 - 0.11 11.6 5.5 0.03 13.5 1.0 1.8 1 1 1 2 2 2 0 Filoviridae VP35 AAA_19 PF13245.1 EGC29726.1 - 0.2 11.4 0.0 0.37 10.5 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain OTU PF02338.14 EGC29728.1 - 1.2e-12 48.5 0.0 1.2e-12 48.5 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC29728.1 - 0.035 12.3 45.1 0.045 12.0 31.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EGC29728.1 - 0.045 13.1 30.5 0.063 12.6 21.2 1.2 1 0 0 1 1 1 0 Vta1 like TFIIA PF03153.8 EGC29728.1 - 0.11 12.3 30.8 0.16 11.8 21.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SAGA-Tad1 PF12767.2 EGC29728.1 - 0.55 9.8 20.0 0.82 9.2 13.8 1.2 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit PHD PF00628.24 EGC29729.1 - 2e-16 59.4 45.6 1.2e-06 28.0 4.4 3.7 3 0 0 3 3 3 3 PHD-finger Prok-RING_1 PF14446.1 EGC29729.1 - 0.00014 21.5 19.2 0.017 14.8 3.2 3.5 3 0 0 3 3 3 3 Prokaryotic RING finger family 1 EVE PF01878.13 EGC29729.1 - 0.00021 21.3 0.0 0.00064 19.7 0.0 1.9 1 0 0 1 1 1 1 EVE domain PHD_2 PF13831.1 EGC29729.1 - 2.1 7.7 30.0 0.091 12.0 2.7 3.7 3 0 0 3 3 3 0 PHD-finger DUF1990 PF09348.5 EGC29730.1 - 6.9e-50 168.7 0.0 8.1e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1990) ATP-grasp_2 PF08442.5 EGC29733.1 - 3.7e-77 258.2 1.4 3.8e-77 258.2 0.2 1.6 2 0 0 2 2 2 1 ATP-grasp domain Ligase_CoA PF00549.14 EGC29733.1 - 7.4e-27 93.8 1.1 1.6e-26 92.7 0.8 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EGC29733.1 - 7.2e-09 35.1 0.1 1.6e-08 34.0 0.1 1.5 1 1 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGC29733.1 - 0.00012 21.6 2.1 0.0022 17.5 0.1 2.6 2 1 0 2 2 2 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATP-grasp_4 PF13535.1 EGC29733.1 - 0.014 15.0 0.0 0.029 14.1 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Succ_CoA_lig PF13607.1 EGC29733.1 - 0.015 14.9 0.2 0.089 12.3 0.1 2.1 1 1 0 1 1 1 0 Succinyl-CoA ligase like flavodoxin domain RasGEF PF00617.14 EGC29734.1 - 4e-54 183.1 2.8 4e-54 183.1 2.0 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC29734.1 - 5.1e-19 68.3 3.9 5.9e-19 68.1 0.8 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif WH1 PF00568.18 EGC29734.1 - 0.0062 16.2 0.1 0.013 15.1 0.1 1.5 1 0 0 1 1 1 1 WH1 domain OCD_Mu_crystall PF02423.10 EGC29736.1 - 2.3e-52 177.7 0.1 2.6e-52 177.5 0.1 1.0 1 0 0 1 1 1 1 Ornithine cyclodeaminase/mu-crystallin family Shikimate_DH PF01488.15 EGC29736.1 - 4e-09 36.6 0.0 7.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_7 PF13241.1 EGC29736.1 - 0.027 14.7 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 Putative NAD(P)-binding Hormone_1 PF00103.15 EGC29737.1 - 0.13 11.6 0.5 0.14 11.4 0.3 1.0 1 0 0 1 1 1 0 Somatotropin hormone family Dabb PF07876.7 EGC29740.1 - 1.1e-18 67.4 0.0 1.3e-18 67.2 0.0 1.0 1 0 0 1 1 1 1 Stress responsive A/B Barrel Domain 2OG-FeII_Oxy_4 PF13661.1 EGC29741.1 - 1.5e-12 46.9 0.1 2.3e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGC29741.1 - 1.1e-05 25.9 0.0 1.6e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily CIMR PF00878.13 EGC29742.1 - 6.1e-10 39.0 15.3 8.8e-05 22.3 3.9 3.5 3 1 0 3 3 3 3 Cation-independent mannose-6-phosphate receptor repeat CH PF00307.26 EGC29742.1 - 0.043 13.8 0.1 2.1 8.4 0.0 2.6 2 0 0 2 2 2 0 Calponin homology (CH) domain SapB_2 PF03489.12 EGC29743.1 - 6.3e-05 22.9 0.1 0.00019 21.3 0.1 1.9 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC29743.1 - 0.013 15.2 0.5 0.047 13.5 0.4 2.0 1 0 0 1 1 1 0 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC29744.1 - 9.2e-05 22.3 0.5 0.00018 21.4 0.0 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC29744.1 - 0.0001 22.0 0.8 0.00027 20.6 0.5 1.8 1 1 0 1 1 1 1 Saposin-like type B, region 1 ACR_tran PF00873.14 EGC29746.1 - 4.1 4.6 12.3 4.8 4.4 8.5 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family DUF948 PF06103.6 EGC29746.1 - 6.1 6.7 11.1 0.66 9.8 2.6 2.7 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) Phi-29_GP4 PF05464.6 EGC29748.1 - 0.36 10.7 2.4 0.46 10.3 0.8 1.7 1 1 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) Clenterotox PF03505.9 EGC29749.1 - 0.059 12.7 0.0 0.079 12.3 0.0 1.4 1 1 0 1 1 1 0 Clostridium enterotoxin PARP PF00644.15 EGC29751.1 - 1.4e-14 53.9 6.2 9.6e-12 44.7 4.3 2.6 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain DUF1768 PF08719.6 EGC29752.1 - 4.7e-38 130.4 0.0 5.4e-38 130.2 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.15 EGC29753.1 - 2.4e-16 59.7 5.1 1.5e-13 50.6 0.5 2.5 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Ubie_methyltran PF01209.13 EGC29754.1 - 5.7e-08 32.1 0.0 5.7e-08 32.1 0.0 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGC29754.1 - 2.3e-05 24.7 0.0 3e-05 24.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29754.1 - 0.0053 16.3 0.0 0.0053 16.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29754.1 - 0.068 13.6 0.0 0.086 13.3 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase domain Med15 PF09606.5 EGC29754.1 - 0.15 10.2 0.0 0.15 10.2 0.0 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal FNIP PF05725.7 EGC29755.1 - 0.0016 18.3 0.0 0.0069 16.3 0.0 1.9 2 0 0 2 2 2 1 FNIP Repeat PARP PF00644.15 EGC29757.1 - 3e-17 62.7 2.4 3.7e-13 49.3 0.0 2.9 1 1 2 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain Antimicrobial_6 PF08036.6 EGC29758.1 - 0.0021 17.7 7.7 0.24 11.1 0.5 3.3 3 0 0 3 3 3 3 Diapausin family of antimicrobial peptide PRKCSH PF07915.8 EGC29758.1 - 0.063 14.0 5.0 2.3 9.0 0.5 2.6 1 1 1 2 2 2 0 Glucosidase II beta subunit-like protein zf-ribbon_3 PF13248.1 EGC29758.1 - 0.95 8.7 15.4 0.14 11.4 0.6 3.4 3 0 0 3 3 3 0 zinc-ribbon domain zf-piccolo PF05715.8 EGC29758.1 - 6.5 6.8 12.9 1.1 9.3 0.6 3.0 3 0 0 3 3 3 0 Piccolo Zn-finger DDE_Tnp_4 PF13359.1 EGC29759.1 - 7.8e-15 54.8 0.0 3.2e-14 52.8 0.0 2.0 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3537 PF12056.3 EGC29759.1 - 0.11 11.2 3.2 0.21 10.2 2.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3537) Methyltransf_11 PF08241.7 EGC29760.1 - 8.5e-12 45.4 0.0 1.2e-11 44.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29760.1 - 1.2e-11 44.3 0.1 1.5e-11 44.1 0.1 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29760.1 - 2.2e-09 37.8 0.0 3.1e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC29760.1 - 4.1e-06 26.0 0.2 6e-06 25.5 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGC29760.1 - 1.5e-05 24.7 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC29760.1 - 6.5e-05 23.2 0.0 0.0001 22.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29760.1 - 0.00065 20.1 0.0 0.00098 19.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC29760.1 - 0.011 15.3 0.0 0.83 9.2 0.0 2.1 2 0 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EGC29760.1 - 0.074 11.3 0.0 0.15 10.3 0.0 1.5 2 0 0 2 2 2 0 Putative S-adenosyl-L-methionine-dependent methyltransferase Methyltransf_32 PF13679.1 EGC29760.1 - 0.13 11.9 0.0 0.17 11.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain EAP30 PF04157.11 EGC29761.1 - 1e-55 188.3 1.3 1e-55 188.3 0.9 2.1 3 0 0 3 3 3 1 EAP30/Vps36 family Vps36_ESCRT-II PF11605.3 EGC29761.1 - 1.2e-13 50.6 0.0 5.1e-13 48.6 0.0 2.2 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 PAT1 PF09770.4 EGC29761.1 - 0.12 10.6 54.6 0.17 10.0 37.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF4407 PF14362.1 EGC29761.1 - 0.62 8.9 10.4 0.14 11.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4407) AIRS_C PF02769.17 EGC29762.1 - 4.2e-24 85.2 0.0 6.1e-24 84.7 0.0 1.2 1 0 0 1 1 1 1 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGC29762.1 - 5.9e-05 23.2 0.0 0.00018 21.7 0.0 1.8 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain RhoGAP PF00620.22 EGC29763.1 - 2.4e-44 150.6 0.1 3.8e-44 149.9 0.1 1.3 1 0 0 1 1 1 1 RhoGAP domain Peptidase_S8 PF00082.17 EGC29764.1 - 1.8e-40 138.9 0.1 1.8e-40 138.9 0.1 1.9 2 0 0 2 2 2 1 Subtilase family Peptidase_C97 PF05903.9 EGC29765.1 - 9.8e-29 100.0 0.3 1.2e-28 99.8 0.2 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain PTS-HPr PF00381.14 EGC29767.1 - 0.025 14.4 0.0 0.039 13.8 0.0 1.3 1 0 0 1 1 1 0 PTS HPr component phosphorylation site RPA_C PF08784.6 EGC29769.1 - 0.014 15.7 5.0 0.027 14.8 3.4 1.5 1 0 0 1 1 1 0 Replication protein A C terminal Ribosomal_L19e PF01280.15 EGC29769.1 - 0.057 13.1 1.6 0.096 12.4 1.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L19e Menin PF05053.8 EGC29769.1 - 0.62 8.1 5.3 0.79 7.8 3.6 1.2 1 0 0 1 1 1 0 Menin FA_hydroxylase PF04116.8 EGC29771.1 - 6.4e-19 68.4 19.0 1.5e-18 67.2 11.9 2.1 2 0 0 2 2 2 1 Fatty acid hydroxylase superfamily Act-Frag_cataly PF09192.5 EGC29772.1 - 8.4e-83 277.5 10.0 1e-82 277.2 6.9 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic SpecificRecomb PF10136.4 EGC29772.1 - 0.054 11.5 0.0 0.071 11.1 0.0 1.1 1 0 0 1 1 1 0 Site-specific recombinase DUF2373 PF10180.4 EGC29773.1 - 6.5e-22 76.8 1.3 1.6e-21 75.6 0.9 1.7 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2373) SnoaL_2 PF12680.2 EGC29774.1 - 4.6e-05 23.7 0.0 5.4e-05 23.5 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGC29774.1 - 0.066 12.8 0.1 0.14 11.7 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase Aldedh PF00171.17 EGC29775.1 - 1.7e-134 448.6 0.0 2.1e-134 448.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGC29775.1 - 0.014 14.6 0.0 0.039 13.1 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1487) LuxC PF05893.9 EGC29775.1 - 0.014 14.1 0.1 0.044 12.5 0.1 1.8 1 1 0 1 1 1 0 Acyl-CoA reductase (LuxC) JmjC PF02373.17 EGC29776.1 - 6.1e-17 61.9 0.3 2.4e-16 59.9 0.0 2.3 2 0 0 2 2 2 1 JmjC domain, hydroxylase PWWP PF00855.12 EGC29776.1 - 0.027 14.6 1.6 0.071 13.3 0.0 2.5 3 0 0 3 3 3 0 PWWP domain Ank_2 PF12796.2 EGC29777.1 - 9.4e-46 154.0 4.6 6.8e-20 71.1 0.9 6.0 2 1 3 7 7 7 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGC29777.1 - 4.6e-40 133.4 0.2 1.5e-09 37.1 0.0 7.7 7 0 0 7 7 7 6 Ankyrin repeat Ank_4 PF13637.1 EGC29777.1 - 2.2e-34 117.2 13.0 8.3e-10 38.9 0.3 7.4 4 1 3 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC29777.1 - 7.5e-28 93.8 10.0 1.2e-06 28.1 0.1 8.6 9 0 0 9 9 9 6 Ankyrin repeat Ank_5 PF13857.1 EGC29777.1 - 5.2e-22 77.3 1.0 2.7e-07 30.6 0.0 6.8 3 2 4 7 7 7 5 Ankyrin repeats (many copies) YfmQ PF10787.4 EGC29777.1 - 0.00086 18.6 0.0 0.013 14.8 0.0 2.5 2 1 0 2 2 2 1 Uncharacterised protein from bacillus cereus group Peptidase_M1 PF01433.15 EGC29778.1 - 1.2e-115 386.7 7.1 3.5e-115 385.2 4.9 1.8 1 1 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGC29778.1 - 1.3e-32 113.3 0.0 1.9e-32 112.8 0.0 1.2 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGC29778.1 - 3.4e-16 59.4 0.0 8.6e-16 58.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase MA superfamily DUF2393 PF09624.5 EGC29778.1 - 0.0039 16.7 9.3 0.039 13.4 2.6 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2393) DUF1360 PF07098.6 EGC29778.1 - 0.045 13.4 2.1 0.074 12.7 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) HPP PF04982.8 EGC29779.1 - 1.4e-42 144.3 5.9 1.4e-42 144.3 4.1 1.6 2 0 0 2 2 2 1 HPP family Wzy_C PF04932.10 EGC29779.1 - 6.4 6.5 7.9 1.2e+02 2.3 5.5 2.4 1 1 0 1 1 1 0 O-Antigen ligase zf-RING_2 PF13639.1 EGC29780.1 - 1.2e-09 37.7 10.7 1.8e-09 37.2 7.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC29780.1 - 1.7e-06 27.9 12.3 2.8e-06 27.2 8.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC29780.1 - 3.5e-06 26.5 12.7 5.2e-06 26.0 8.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29780.1 - 3.4e-05 23.3 13.1 6.4e-05 22.5 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29780.1 - 4.2e-05 23.5 6.0 7.7e-05 22.7 4.2 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC29780.1 - 0.00013 21.6 13.3 0.00025 20.6 9.2 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC29780.1 - 0.0004 20.0 6.5 0.002 17.8 4.0 2.4 1 1 1 2 2 2 1 RING-type zinc-finger DUF1272 PF06906.6 EGC29780.1 - 0.011 15.5 8.8 0.02 14.7 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-UDP PF14569.1 EGC29780.1 - 0.031 13.9 2.7 0.086 12.6 1.9 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-C3HC4_4 PF15227.1 EGC29780.1 - 0.05 13.4 13.1 0.33 10.8 9.2 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC29780.1 - 0.08 12.4 6.3 0.16 11.5 4.4 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EGC29780.1 - 0.21 11.1 10.2 0.51 9.9 7.1 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGC29780.1 - 0.25 11.0 8.6 0.38 10.4 5.9 1.4 1 1 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-P11 PF03854.9 EGC29780.1 - 0.54 9.7 10.6 0.18 11.3 3.5 2.2 1 1 1 2 2 2 0 P-11 zinc finger CDC45 PF02724.9 EGC29780.1 - 1.7 6.5 8.0 0.22 9.5 3.0 1.3 2 0 0 2 2 2 0 CDC45-like protein SH3_1 PF00018.23 EGC29781.1 - 2.3e-15 55.7 2.2 2.5e-15 55.5 0.1 2.1 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGC29781.1 - 6.2e-15 54.5 1.2 1.8e-14 53.0 0.1 2.3 2 1 1 3 3 3 1 Variant SH3 domain SH3_2 PF07653.12 EGC29781.1 - 1.1e-11 44.0 0.0 2.4e-11 42.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Cofilin_ADF PF00241.15 EGC29781.1 - 2.5e-10 40.3 1.0 3.9e-10 39.7 0.0 1.9 2 0 0 2 2 2 1 Cofilin/tropomyosin-type actin-binding protein AAA_17 PF13207.1 EGC29782.1 - 2.3e-07 31.6 0.0 9.1e-07 29.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC29782.1 - 4.8e-06 26.9 0.3 4.8e-06 26.9 0.2 3.4 3 1 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EGC29782.1 - 0.00028 20.0 0.0 0.00065 18.8 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGC29782.1 - 0.0014 18.5 0.0 0.0036 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC29782.1 - 0.0037 17.2 0.0 0.0064 16.4 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC29782.1 - 0.025 14.5 0.0 0.048 13.6 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DDHD PF02862.12 EGC29782.1 - 0.032 14.0 9.6 0.14 11.9 4.8 2.2 2 0 0 2 2 2 0 DDHD domain APS_kinase PF01583.15 EGC29782.1 - 0.082 12.5 0.1 0.15 11.7 0.1 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase Pex14_N PF04695.8 EGC29782.1 - 0.22 11.5 0.1 0.22 11.5 0.1 3.1 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ABC_tran PF00005.22 EGC29782.1 - 0.41 10.9 8.8 0.16 12.2 1.1 3.0 2 1 0 2 2 2 0 ABC transporter Peptidase_M49 PF03571.10 EGC29783.1 - 7.1e-218 724.1 0.5 8.5e-218 723.8 0.4 1.0 1 0 0 1 1 1 1 Peptidase family M49 2C_adapt PF08793.5 EGC29783.1 - 0.074 12.9 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 2-cysteine adaptor domain Glyoxalase PF00903.20 EGC29785.1 - 1.9e-11 44.0 0.1 1.3e-10 41.3 0.0 2.0 2 0 0 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGC29785.1 - 0.00017 21.5 0.0 0.03 14.3 0.0 2.9 3 0 0 3 3 3 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EGC29785.1 - 0.05 13.5 0.1 0.33 10.8 0.0 2.2 2 0 0 2 2 2 0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal CN_hydrolase PF00795.17 EGC29787.1 - 3.9e-28 98.0 0.0 1.1e-27 96.5 0.0 1.6 2 0 0 2 2 2 1 Carbon-nitrogen hydrolase Laminin_EGF PF00053.19 EGC29788.1 - 0.0091 15.9 0.5 0.0091 15.9 0.3 2.1 2 0 0 2 2 2 1 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC29788.1 - 0.028 14.4 1.4 0.028 14.4 1.0 2.2 2 0 0 2 2 2 0 Human growth factor-like EGF Pkinase PF00069.20 EGC29789.1 - 1.5e-71 240.5 0.2 2.7e-71 239.7 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29789.1 - 3.7e-35 121.2 0.0 6.3e-35 120.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC29789.1 - 2.3e-06 26.8 0.1 4.2e-06 25.9 0.0 1.5 1 1 0 1 1 1 1 Kinase-like APH PF01636.18 EGC29789.1 - 0.054 13.2 0.0 0.38 10.4 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family T2SM PF04612.7 EGC29789.1 - 0.33 10.7 7.7 0.55 10.0 5.4 1.2 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein M Methyltransf_26 PF13659.1 EGC29790.1 - 1.8e-11 44.0 0.0 3e-11 43.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGC29790.1 - 5.1e-11 42.4 0.0 1.1e-10 41.3 0.0 1.5 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 N6_N4_Mtase PF01555.13 EGC29790.1 - 0.00014 21.4 0.1 0.00014 21.4 0.0 3.0 2 2 0 2 2 2 1 DNA methylase DUF2971 PF11185.3 EGC29790.1 - 0.82 10.4 7.2 3.1 8.5 3.1 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF2971) CWC25 PF12542.3 EGC29792.1 - 5.2e-15 55.6 0.9 5.2e-15 55.6 0.6 6.4 3 1 1 4 4 4 1 Pre-mRNA splicing factor Cir_N PF10197.4 EGC29792.1 - 4e-12 45.9 14.8 4e-12 45.9 10.3 7.9 6 2 0 6 6 6 1 N-terminal domain of CBF1 interacting co-repressor CIR Gryzun-like PF12742.2 EGC29794.1 - 0.095 12.5 0.7 0.17 11.7 0.2 1.6 1 1 1 2 2 2 0 Gryzun, putative Golgi trafficking Cir_N PF10197.4 EGC29795.1 - 3e-10 39.9 6.9 3e-10 39.9 4.8 4.0 3 1 0 3 3 3 1 N-terminal domain of CBF1 interacting co-repressor CIR DUF4414 PF14377.1 EGC29795.1 - 0.027 14.3 23.1 0.071 13.0 4.7 3.3 2 2 0 2 2 2 0 Domain of unknown function (DUF4414) zf-CCHC_6 PF15288.1 EGC29795.1 - 0.03 14.0 0.8 0.03 14.0 0.6 2.3 2 0 0 2 2 2 0 Zinc knuckle CAF-1_p150 PF11600.3 EGC29795.1 - 4.3 6.6 65.9 1.7 8.0 15.2 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Pkinase PF00069.20 EGC29796.1 - 1e-09 37.9 1.9 1e-09 37.9 1.3 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29796.1 - 5.9e-06 25.5 0.2 1e-05 24.7 0.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase AATF-Che1 PF13339.1 EGC29796.1 - 0.054 13.6 3.7 0.11 12.6 2.2 1.6 1 1 0 1 1 1 0 Apoptosis antagonizing transcription factor DUF4404 PF14357.1 EGC29796.1 - 0.17 12.3 2.0 0.37 11.2 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Zip PF02535.17 EGC29798.1 - 0.007 15.4 0.4 0.0075 15.3 0.3 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter RhoGAP PF00620.22 EGC29799.1 - 1.1e-26 93.2 2.9 1.5e-26 92.8 0.1 2.7 3 0 0 3 3 3 1 RhoGAP domain FCH PF00611.18 EGC29799.1 - 7.7e-11 42.0 0.3 7.7e-11 42.0 0.2 3.2 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SR-25 PF10500.4 EGC29799.1 - 0.0031 17.0 22.7 0.0031 17.0 15.7 3.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Prefoldin_2 PF01920.15 EGC29800.1 - 9.5e-14 51.0 7.1 1.1e-13 50.8 4.9 1.1 1 0 0 1 1 1 1 Prefoldin subunit LEDGF PF11467.3 EGC29800.1 - 0.036 13.7 0.8 0.057 13.1 0.3 1.6 1 1 0 1 1 1 0 Lens epithelium-derived growth factor (LEDGF) Mod_r PF07200.8 EGC29800.1 - 0.038 13.8 0.6 0.038 13.8 0.4 1.7 1 1 1 2 2 2 0 Modifier of rudimentary (Mod(r)) protein PT-HINT PF07591.6 EGC29800.1 - 0.054 13.3 0.2 0.074 12.9 0.1 1.3 1 1 0 1 1 1 0 Pretoxin HINT domain Syntaxin-6_N PF09177.6 EGC29800.1 - 0.13 12.6 1.6 1.1 9.6 0.1 2.1 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Tropomyosin PF00261.15 EGC29800.1 - 0.39 9.7 6.7 0.22 10.5 0.3 2.0 1 1 1 2 2 2 0 Tropomyosin Seryl_tRNA_N PF02403.17 EGC29800.1 - 4.1 7.4 8.7 4.9 7.2 1.3 2.1 1 1 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ubiquitin_3 PF14836.1 EGC29802.1 - 0.054 13.1 0.1 0.061 12.9 0.1 1.2 1 0 0 1 1 1 0 Ubiquitin-like domain EI24 PF07264.6 EGC29803.1 - 0.034 13.5 0.0 0.042 13.2 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) EF-hand_7 PF13499.1 EGC29805.1 - 5.6e-20 71.2 2.1 1.2e-07 31.7 0.0 4.6 3 2 1 4 4 4 4 EF-hand domain pair EF-hand_1 PF00036.27 EGC29805.1 - 4.4e-18 63.1 10.4 5.7e-05 22.1 0.1 6.1 7 0 0 7 7 7 3 EF hand EF-hand_6 PF13405.1 EGC29805.1 - 6.5e-15 53.6 6.4 0.0056 16.4 0.0 6.5 5 1 1 6 6 6 3 EF-hand domain EF-hand_8 PF13833.1 EGC29805.1 - 1.2e-13 50.4 7.9 0.00054 19.5 0.0 4.6 4 1 1 5 5 5 3 EF-hand domain pair EF-hand_5 PF13202.1 EGC29805.1 - 5.3e-10 38.1 10.6 0.00024 20.2 0.2 4.1 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EGC29805.1 - 1.1e-06 28.3 3.2 0.27 11.0 0.0 4.3 3 1 1 4 4 4 3 Cytoskeletal-regulatory complex EF hand VCBS PF13517.1 EGC29805.1 - 0.00011 22.4 0.1 0.2 12.0 0.0 3.1 3 0 0 3 3 3 2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella SPARC_Ca_bdg PF10591.4 EGC29805.1 - 0.00027 20.9 1.1 0.0073 16.3 0.0 3.3 4 0 0 4 4 4 1 Secreted protein acidic and rich in cysteine Ca binding region TcdB_toxin_midN PF12256.3 EGC29805.1 - 0.0054 16.2 0.0 3.7 6.9 0.0 2.5 2 0 0 2 2 2 2 Insecticide toxin TcdB middle/N-terminal region FG-GAP PF01839.18 EGC29805.1 - 0.012 15.3 1.4 2.4 7.9 0.0 2.4 2 0 0 2 2 2 0 FG-GAP repeat EFhand_Ca_insen PF08726.5 EGC29805.1 - 0.025 14.5 0.0 0.081 12.9 0.0 1.9 1 0 0 1 1 1 0 Ca2+ insensitive EF hand EF-hand_9 PF14658.1 EGC29805.1 - 0.044 13.6 0.0 14 5.6 0.0 3.2 3 0 0 3 3 3 0 EF-hand domain DUF1191 PF06697.7 EGC29805.1 - 0.07 11.9 0.0 0.14 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) TetR_C_8 PF14278.1 EGC29805.1 - 1.8 9.0 9.2 5.1 7.5 0.1 4.6 4 1 1 5 5 5 0 Transcriptional regulator C-terminal region PIP5K PF01504.13 EGC29806.1 - 7.9e-60 202.0 9.2 1.7e-59 200.9 6.3 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DSPc PF00782.15 EGC29808.1 - 5.2e-29 100.5 0.0 2.2e-28 98.4 0.0 2.2 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain LRR_8 PF13855.1 EGC29808.1 - 4.2e-19 68.0 29.0 8.1e-08 31.9 5.0 5.5 3 2 2 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EGC29808.1 - 2.2e-17 62.2 37.7 3.3e-08 32.9 2.0 6.2 4 2 2 6 6 6 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC29808.1 - 5e-14 50.1 37.4 0.16 12.0 0.1 10.5 10 0 0 10 10 10 7 Leucine Rich Repeat LRR_7 PF13504.1 EGC29808.1 - 5.9e-05 22.6 22.3 5.7 7.5 0.3 9.2 9 0 0 9 9 9 1 Leucine rich repeat LRR_9 PF14580.1 EGC29808.1 - 0.00037 20.0 4.7 0.014 14.9 0.8 2.3 1 1 1 2 2 2 2 Leucine-rich repeat Y_phosphatase PF00102.22 EGC29808.1 - 0.0026 17.1 0.0 0.0055 16.0 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Ank_2 PF12796.2 EGC29810.1 - 8.8e-27 93.2 4.8 1e-11 45.0 0.1 4.3 3 2 2 5 5 5 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC29810.1 - 1.8e-23 81.1 6.6 1.7e-07 30.7 0.0 6.0 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EGC29810.1 - 3.6e-19 68.3 0.2 2.5e-09 37.0 0.1 5.4 7 0 0 7 7 7 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC29810.1 - 5.1e-17 61.8 7.8 1.1e-06 28.9 0.1 5.0 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC29810.1 - 6.5e-15 53.7 1.8 0.065 13.5 0.0 5.7 5 0 0 5 5 5 3 Ankyrin repeat zf-C3HC4_3 PF13920.1 EGC29810.1 - 2.3e-10 39.9 8.7 2.3e-10 39.9 6.0 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29810.1 - 0.0068 16.4 9.8 0.017 15.1 6.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) ChaC PF04752.7 EGC29811.1 - 1.3e-39 135.9 0.0 1.7e-39 135.5 0.0 1.1 1 0 0 1 1 1 1 ChaC-like protein PUA PF01472.15 EGC29811.1 - 5.2e-18 64.5 0.0 9e-18 63.7 0.0 1.3 1 0 0 1 1 1 1 PUA domain AIG2 PF06094.7 EGC29811.1 - 6.4e-06 26.5 0.0 1.1e-05 25.8 0.0 1.3 1 0 0 1 1 1 1 AIG2-like family TPR_11 PF13414.1 EGC29813.1 - 0.38 10.4 1.4 1.4 8.6 0.1 2.2 2 0 0 2 2 2 0 TPR repeat Acyltransferase PF01553.16 EGC29814.1 - 9.3e-15 54.2 0.0 1.4e-14 53.6 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase DUF3997 PF13162.1 EGC29814.1 - 0.068 12.9 1.2 0.3 10.9 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3997) DUF4389 PF14333.1 EGC29814.1 - 2 8.1 9.0 4.1 7.1 2.3 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Sld5 PF05916.6 EGC29815.1 - 2.8e-05 24.3 0.2 4.7e-05 23.6 0.2 1.4 1 0 0 1 1 1 1 GINS complex protein DUF2057 PF09829.4 EGC29815.1 - 0.06 12.9 0.0 0.1 12.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2057) CD20 PF04103.10 EGC29816.1 - 0.0056 16.6 14.6 0.0075 16.1 10.1 1.2 1 0 0 1 1 1 1 CD20-like family CcoS PF03597.10 EGC29816.1 - 2.6 7.5 7.3 7 6.1 0.2 3.1 3 0 0 3 3 3 0 Cytochrome oxidase maturation protein cbb3-type SdpI PF13630.1 EGC29816.1 - 3.4 7.4 16.1 0.94 9.2 5.3 2.9 2 1 1 3 3 3 0 SdpI/YhfL protein family TSLP PF15216.1 EGC29818.1 - 0.081 12.6 0.5 0.096 12.4 0.4 1.1 1 0 0 1 1 1 0 Thymic stromal lymphopoietin ketoacyl-synt PF00109.21 EGC29819.1 - 4.4e-60 203.2 0.0 1.3e-59 201.7 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EGC29819.1 - 3.8e-44 150.4 0.0 8.4e-44 149.3 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC29819.1 - 2.4e-42 145.3 0.0 3.9e-42 144.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC29819.1 - 1.7e-30 105.3 0.0 6e-30 103.5 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC29819.1 - 9.9e-26 90.4 0.0 1.3e-24 86.8 0.0 2.3 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGC29819.1 - 1.5e-22 80.0 0.0 2.3e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC29819.1 - 3.3e-21 75.8 0.0 3.1e-18 66.2 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EGC29819.1 - 9.4e-21 74.1 3.7 1.1e-20 73.9 0.0 3.3 3 0 0 3 3 1 1 Methyltransferase domain Epimerase PF01370.16 EGC29819.1 - 3e-14 53.0 0.0 1.6e-08 34.3 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC29819.1 - 1.4e-08 35.6 0.0 3.4e-08 34.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC29819.1 - 9.8e-08 31.7 0.1 2.2e-07 30.5 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EGC29819.1 - 1.7e-06 28.1 0.2 3.6e-05 23.9 0.3 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EGC29819.1 - 7.9e-06 26.2 0.0 4.7e-05 23.8 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29819.1 - 9.3e-06 25.4 0.0 2.7e-05 23.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29819.1 - 0.00047 20.7 0.0 0.002 18.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC29819.1 - 0.003 16.5 0.0 0.0065 15.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC29820.1 - 3.6e-61 206.8 0.0 9.1e-61 205.5 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC29820.1 - 2.3e-45 155.2 0.0 3.7e-45 154.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC29820.1 - 5.2e-43 146.7 0.0 1.1e-42 145.7 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC29820.1 - 1.3e-31 108.8 0.0 4.1e-31 107.3 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC29820.1 - 1.9e-24 86.2 0.0 1.3e-22 80.3 0.0 2.5 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC29820.1 - 3.9e-22 78.5 0.0 5.2e-21 74.9 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 EGC29820.1 - 4e-22 78.7 0.0 6.2e-22 78.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC29820.1 - 2.7e-19 69.6 0.0 2.7e-15 56.7 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 EGC29820.1 - 2.5e-11 43.4 0.1 1.6e-07 31.0 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC29820.1 - 1.1e-08 35.9 0.0 2.6e-08 34.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC29820.1 - 1.4e-07 31.2 0.0 3.5e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC29820.1 - 4.3e-06 27.1 0.0 2.8e-05 24.5 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29820.1 - 2.3e-05 24.1 0.0 6.4e-05 22.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC29820.1 - 4.9e-05 23.5 0.1 0.00015 21.9 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EGC29820.1 - 8.6e-05 23.0 0.0 0.00036 21.0 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC29820.1 - 0.0021 17.1 0.0 0.005 15.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glycos_transf_4 PF00953.16 EGC29822.1 - 1.3e-35 122.5 14.1 1.3e-35 122.5 9.8 2.0 3 1 0 3 3 3 1 Glycosyl transferase family 4 DUF1270 PF06900.6 EGC29823.1 - 0.05 13.7 0.1 0.092 12.8 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1270) Baculo_11_kDa PF06143.6 EGC29823.1 - 0.092 12.1 0.3 0.13 11.6 0.2 1.2 1 0 0 1 1 1 0 Baculovirus 11 kDa family Mitochondr_Som1 PF11093.3 EGC29823.1 - 0.13 12.0 0.7 0.17 11.7 0.5 1.2 1 0 0 1 1 1 0 Mitochondrial export protein Som1 DUF1313 PF07011.6 EGC29824.1 - 0.093 12.4 2.4 0.11 12.1 1.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1313) Plasmod_dom_1 PF09715.5 EGC29824.1 - 0.32 10.9 2.5 1.2 9.0 1.8 1.7 1 1 1 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) Complex1_LYR PF05347.10 EGC29825.1 - 2.3e-17 62.5 0.9 3.2e-17 62.0 0.6 1.2 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC29825.1 - 1e-15 57.6 1.0 1.4e-15 57.2 0.7 1.2 1 0 0 1 1 1 1 Complex1_LYR-like Pox_MCEL PF03291.11 EGC29826.1 - 1.9e-69 234.0 12.0 1.9e-69 234.0 8.3 2.2 1 1 0 2 2 2 1 mRNA capping enzyme Ubie_methyltran PF01209.13 EGC29826.1 - 0.0001 21.5 0.5 0.0003 19.9 0.2 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGC29826.1 - 0.0001 22.5 0.4 0.00036 20.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29826.1 - 0.00012 22.4 0.1 0.00012 22.4 0.1 3.7 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC29826.1 - 0.00013 22.3 1.3 0.00027 21.3 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGC29826.1 - 0.0042 16.0 0.0 0.0042 16.0 0.0 2.2 2 1 0 2 2 2 1 NNMT/PNMT/TEMT family RRM_1 PF00076.17 EGC29827.1 - 1.7e-66 219.8 8.2 7.1e-19 67.2 0.4 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC29827.1 - 3.1e-45 152.0 0.7 1.4e-12 47.4 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC29827.1 - 1.2e-34 117.9 2.8 4.3e-10 39.2 0.1 4.7 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGC29827.1 - 4.9e-09 35.7 0.1 1.1e-08 34.6 0.1 1.6 1 0 0 1 1 1 1 Poly-adenylate binding protein, unique domain RRM_3 PF08777.6 EGC29827.1 - 4.8e-08 32.8 5.4 0.032 14.0 0.3 4.1 3 1 1 4 4 4 2 RNA binding motif Nup35_RRM PF05172.8 EGC29827.1 - 0.00059 19.5 2.6 0.26 11.0 0.1 3.7 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGC29827.1 - 0.0012 18.5 0.0 9.7 6.0 0.0 3.5 2 1 1 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 EGC29827.1 - 0.023 14.4 1.0 29 4.5 0.0 3.7 4 0 0 4 4 4 0 Nup53/35/40-type RNA recognition motif Peptidase_M48 PF01435.13 EGC29828.1 - 2.9e-39 134.9 0.1 6.5e-39 133.8 0.1 1.5 1 1 0 1 1 1 1 Peptidase family M48 Pkinase PF00069.20 EGC29829.1 - 6e-67 225.5 0.0 1.3e-66 224.4 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29829.1 - 4.2e-47 160.3 0.1 6.6e-47 159.7 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC29829.1 - 0.0001 21.3 0.1 0.00044 19.2 0.1 1.9 1 1 1 2 2 2 1 Kinase-like RIO1 PF01163.17 EGC29829.1 - 0.00011 21.6 0.2 0.00021 20.6 0.1 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC29829.1 - 0.0012 18.5 0.0 0.013 15.2 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC29829.1 - 0.042 12.9 0.0 0.075 12.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Arf PF00025.16 EGC29830.1 - 4.3e-43 146.5 0.0 5.2e-43 146.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC29830.1 - 6.7e-09 35.2 0.0 8.3e-09 34.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC29830.1 - 3.4e-08 33.0 0.0 3.9e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC29830.1 - 1.1e-07 32.3 0.0 2.5e-07 31.2 0.0 1.6 2 0 0 2 2 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC29830.1 - 5.3e-06 26.3 0.1 7.5e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC29830.1 - 8.6e-06 24.6 0.5 0.0026 16.5 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit NAD_binding_2 PF03446.10 EGC29830.1 - 0.0025 17.6 0.0 0.0035 17.1 0.0 1.1 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Gtr1_RagA PF04670.7 EGC29830.1 - 0.0065 15.6 0.0 0.0085 15.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FtsK_SpoIIIE PF01580.13 EGC29830.1 - 0.0083 15.6 0.1 0.019 14.4 0.0 1.5 2 0 0 2 2 2 1 FtsK/SpoIIIE family GTP_EFTU PF00009.22 EGC29830.1 - 0.036 13.4 0.2 0.67 9.3 0.1 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EGC29830.1 - 0.038 13.8 0.1 0.077 12.9 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC29830.1 - 0.04 14.2 0.5 0.11 12.8 0.4 1.7 1 1 0 1 1 1 0 ABC transporter Dynamin_N PF00350.18 EGC29830.1 - 0.12 12.1 0.5 10 5.8 0.0 2.1 1 1 1 2 2 2 0 Dynamin family Pkinase PF00069.20 EGC29831.1 - 6.8e-63 212.2 0.0 6.8e-63 212.2 0.0 2.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29831.1 - 9.1e-22 77.3 0.0 9.1e-22 77.3 0.0 2.2 2 1 1 3 3 3 1 Protein tyrosine kinase Borrelia_P83 PF05262.6 EGC29831.1 - 8.2 4.5 37.2 14 3.7 25.8 1.4 1 0 0 1 1 1 0 Borrelia P83/100 protein M-factor PF03855.8 EGC29832.1 - 8.2 6.5 8.3 4.2 7.4 0.8 3.1 3 0 0 3 3 3 0 M-factor SET PF00856.23 EGC29833.1 - 2.9e-12 47.2 1.2 5.5e-12 46.2 0.0 1.9 2 0 0 2 2 2 1 SET domain zf-MYND PF01753.13 EGC29833.1 - 4.1e-05 23.3 11.0 4.1e-05 23.3 7.7 1.8 2 0 0 2 2 2 1 MYND finger zf-HIT PF04438.11 EGC29833.1 - 3.4 7.3 12.6 0.083 12.5 2.7 2.4 2 0 0 2 2 2 0 HIT zinc finger Alk_phosphatase PF00245.15 EGC29834.1 - 5.6e-87 292.1 4.3 2.6e-86 289.9 3.0 2.0 1 1 0 1 1 1 1 Alkaline phosphatase Metalloenzyme PF01676.13 EGC29834.1 - 0.0013 18.1 1.7 0.0024 17.3 0.1 2.1 2 0 0 2 2 2 1 Metalloenzyme superfamily DTW PF03942.10 EGC29835.1 - 3.1e-24 85.3 1.0 5.1e-24 84.6 0.7 1.3 1 0 0 1 1 1 1 DTW domain Membralin PF09746.4 EGC29835.1 - 0.12 11.4 2.1 0.34 9.9 1.5 1.7 1 0 0 1 1 1 0 Tumour-associated protein NTR PF01759.16 EGC29835.1 - 0.23 11.0 4.2 0.39 10.2 1.3 2.5 2 0 0 2 2 2 0 UNC-6/NTR/C345C module BPL_N PF09825.4 EGC29835.1 - 1.7 7.3 7.4 5.6 5.6 5.1 1.9 1 1 0 1 1 1 0 Biotin-protein ligase, N terminal EF-hand_1 PF00036.27 EGC29837.1 - 8.2e-16 56.0 9.7 2.7e-07 29.3 0.2 4.0 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EGC29837.1 - 1.1e-15 57.4 7.7 7.1e-13 48.4 2.5 2.7 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC29837.1 - 1.6e-14 52.3 8.0 7.6e-07 28.5 0.2 3.5 3 0 0 3 3 3 3 EF-hand domain EF-hand_8 PF13833.1 EGC29837.1 - 4.7e-14 51.7 8.4 6.5e-12 44.8 1.9 3.0 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC29837.1 - 4.8e-08 31.9 11.7 3.5e-06 26.0 0.6 3.3 3 0 0 3 3 3 2 EF hand EF-hand_9 PF14658.1 EGC29837.1 - 0.00019 21.2 0.3 0.0016 18.2 0.2 2.2 2 1 0 2 2 2 1 EF-hand domain EFhand_Ca_insen PF08726.5 EGC29837.1 - 0.034 14.1 0.7 0.75 9.8 0.2 2.6 2 1 1 3 3 3 0 Ca2+ insensitive EF hand DUF3349 PF11829.3 EGC29837.1 - 0.078 13.4 0.2 0.84 10.1 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3349) EF-hand_4 PF12763.2 EGC29837.1 - 0.21 11.3 6.6 6.9 6.4 0.3 3.1 1 1 1 3 3 3 0 Cytoskeletal-regulatory complex EF hand Arm PF00514.18 EGC29838.1 - 7.5e-05 22.4 2.5 0.41 10.5 0.0 3.2 3 0 0 3 3 3 2 Armadillo/beta-catenin-like repeat MinE PF03776.9 EGC29839.1 - 2.1e-12 46.3 0.7 2.8e-12 45.9 0.5 1.2 1 0 0 1 1 1 1 Septum formation topological specificity factor MinE Colicin_immun PF09204.5 EGC29839.1 - 0.019 15.0 0.3 0.022 14.8 0.2 1.2 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity CHB_HEX PF03173.8 EGC29839.1 - 0.064 12.6 0.2 0.15 11.5 0.1 1.7 1 1 0 1 1 1 0 Putative carbohydrate binding domain Decorin_bind PF02352.10 EGC29839.1 - 0.066 13.2 0.9 0.081 12.9 0.6 1.1 1 0 0 1 1 1 0 Decorin binding protein Membrane_bind PF14564.1 EGC29840.1 - 5.5e-26 90.8 2.4 7.5e-26 90.4 0.8 1.9 1 1 0 1 1 1 1 Membrane binding DUF3531 PF12049.3 EGC29840.1 - 0.078 12.6 0.2 0.16 11.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3531) Peptidase_S9 PF00326.16 EGC29841.1 - 8.5e-30 103.5 0.0 1.5e-29 102.7 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGC29841.1 - 2.9e-12 46.9 0.0 4.8e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC29841.1 - 4.4e-11 42.7 0.0 8.9e-11 41.7 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGC29841.1 - 3.2e-07 30.1 0.0 6.3e-07 29.1 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EGC29841.1 - 0.00053 19.3 0.0 0.08 12.2 0.0 2.2 2 0 0 2 2 2 1 Dienelactone hydrolase family BAAT_C PF08840.6 EGC29841.1 - 0.00067 19.4 0.0 0.0019 17.9 0.0 1.7 1 0 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EGC29841.1 - 0.00095 18.6 0.0 0.0023 17.3 0.0 1.6 1 0 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EGC29841.1 - 0.013 15.0 0.0 0.94 8.9 0.0 2.4 1 1 1 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGC29841.1 - 0.023 14.1 0.1 3.8 6.8 0.0 2.5 2 1 0 2 2 2 0 Phospholipase/Carboxylesterase UPF0227 PF05728.7 EGC29841.1 - 0.028 14.1 0.0 0.069 12.8 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) AAA_18 PF13238.1 EGC29842.1 - 7.1e-22 78.0 0.0 1.3e-21 77.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC29842.1 - 1.8e-11 44.9 0.1 3.3e-11 44.0 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGC29842.1 - 7.7e-05 22.8 0.0 0.00017 21.7 0.0 1.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGC29842.1 - 0.00097 19.1 0.0 0.0036 17.3 0.0 1.9 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_33 PF13671.1 EGC29842.1 - 0.0011 18.7 0.0 0.0042 16.9 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC29842.1 - 0.0017 18.3 0.0 0.0034 17.3 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC29842.1 - 0.0019 18.2 0.0 0.0034 17.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SKI PF01202.17 EGC29842.1 - 0.0021 17.9 0.1 0.0072 16.2 0.0 1.8 1 1 0 1 1 1 1 Shikimate kinase AAA_19 PF13245.1 EGC29842.1 - 0.0034 17.1 0.0 0.0072 16.0 0.0 1.5 2 0 0 2 2 1 1 Part of AAA domain DUF815 PF05673.8 EGC29842.1 - 0.0056 15.6 0.0 0.021 13.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) IstB_IS21 PF01695.12 EGC29842.1 - 0.0063 15.9 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein ResIII PF04851.10 EGC29842.1 - 0.0076 16.1 0.0 0.02 14.7 0.0 1.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit RuvB_N PF05496.7 EGC29842.1 - 0.0085 15.1 0.0 0.013 14.5 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_29 PF13555.1 EGC29842.1 - 0.0091 15.5 0.1 0.025 14.1 0.0 1.7 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF2075 PF09848.4 EGC29842.1 - 0.011 14.7 0.0 0.022 13.7 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activat PF00158.21 EGC29842.1 - 0.011 15.1 0.0 0.016 14.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain NTPase_1 PF03266.10 EGC29842.1 - 0.011 15.4 0.0 0.041 13.5 0.0 1.8 2 0 0 2 2 2 0 NTPase ABC_tran PF00005.22 EGC29842.1 - 0.013 15.7 0.2 0.039 14.2 0.1 1.9 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EGC29842.1 - 0.015 14.9 0.0 0.018 14.6 0.0 1.1 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EGC29842.1 - 0.015 14.1 0.0 0.023 13.4 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family RNA_helicase PF00910.17 EGC29842.1 - 0.015 15.4 0.0 0.028 14.5 0.0 1.5 1 0 0 1 1 1 0 RNA helicase AAA_22 PF13401.1 EGC29842.1 - 0.017 15.2 0.0 0.033 14.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGC29842.1 - 0.021 14.0 0.0 0.17 11.1 0.0 2.1 2 1 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EGC29842.1 - 0.024 13.5 0.2 0.099 11.4 0.0 1.8 2 0 0 2 2 2 0 NB-ARC domain AAA_5 PF07728.9 EGC29842.1 - 0.029 14.1 0.0 0.05 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGC29842.1 - 0.037 13.9 0.0 0.12 12.2 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGC29842.1 - 0.038 13.4 0.0 0.078 12.4 0.0 1.6 2 0 0 2 2 2 0 AAA-like domain FtsK_SpoIIIE PF01580.13 EGC29842.1 - 0.043 13.2 0.1 0.068 12.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EGC29842.1 - 0.051 12.6 0.0 0.098 11.7 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGC29842.1 - 0.073 12.6 0.0 0.14 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain KTI12 PF08433.5 EGC29842.1 - 0.073 12.2 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_30 PF13604.1 EGC29842.1 - 0.091 12.3 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGC29842.1 - 0.091 12.1 0.0 0.33 10.3 0.0 1.8 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC29842.1 - 0.092 11.9 0.0 0.18 10.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 KaiC PF06745.8 EGC29842.1 - 0.11 11.6 0.2 0.26 10.3 0.0 1.7 2 0 0 2 2 2 0 KaiC Mg_chelatase PF01078.16 EGC29842.1 - 0.15 11.2 0.0 0.25 10.4 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI THUMP PF02926.12 EGC29843.1 - 5.2e-10 39.3 0.7 1.5e-09 37.9 0.5 1.8 1 0 0 1 1 1 1 THUMP domain BLOC1_2 PF10046.4 EGC29844.1 - 3.9e-32 110.3 6.8 7.2e-32 109.4 4.7 1.4 1 0 0 1 1 1 1 Biogenesis of lysosome-related organelles complex-1 subunit 2 Nsp1_C PF05064.8 EGC29844.1 - 0.0064 16.1 0.4 0.015 14.9 0.3 1.7 1 0 0 1 1 1 1 Nsp1-like C-terminal region IncA PF04156.9 EGC29844.1 - 0.0084 15.7 0.4 0.013 15.1 0.3 1.3 1 0 0 1 1 1 1 IncA protein HsbA PF12296.3 EGC29844.1 - 0.012 15.4 0.9 0.84 9.5 0.3 2.4 2 0 0 2 2 2 0 Hydrophobic surface binding protein A ORF6C PF10552.4 EGC29844.1 - 0.014 15.1 2.6 0.014 15.1 0.4 1.9 2 0 0 2 2 2 0 ORF6C domain DUF4201 PF13870.1 EGC29844.1 - 0.015 14.7 1.1 0.025 14.0 0.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4201) Tropomyosin_1 PF12718.2 EGC29844.1 - 0.017 15.0 1.9 0.03 14.1 1.2 1.5 1 1 0 1 1 1 0 Tropomyosin like Med9 PF07544.8 EGC29844.1 - 0.018 14.7 1.9 0.019 14.6 0.1 1.9 2 1 1 3 3 3 0 RNA polymerase II transcription mediator complex subunit 9 DUF948 PF06103.6 EGC29844.1 - 0.023 14.5 2.9 0.19 11.5 0.4 2.9 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF948) AAA_13 PF13166.1 EGC29844.1 - 0.026 12.9 9.3 0.032 12.7 6.4 1.1 1 0 0 1 1 1 0 AAA domain Glyco_hydro_38 PF01074.17 EGC29844.1 - 0.029 13.6 0.8 0.039 13.2 0.6 1.3 1 1 0 1 1 1 0 Glycosyl hydrolases family 38 N-terminal domain Laminin_II PF06009.7 EGC29844.1 - 0.032 13.9 3.8 1.5 8.5 0.5 2.4 1 1 1 2 2 2 0 Laminin Domain II Osmo_CC PF08946.5 EGC29844.1 - 0.034 14.1 3.4 1.2 9.2 0.1 2.4 1 1 1 2 2 2 0 Osmosensory transporter coiled coil V_ATPase_I PF01496.14 EGC29844.1 - 0.036 11.9 1.3 0.041 11.7 0.9 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family XhlA PF10779.4 EGC29844.1 - 0.053 13.4 1.1 0.15 12.0 0.7 1.7 1 0 0 1 1 1 0 Haemolysin XhlA DUF4463 PF14703.1 EGC29844.1 - 0.057 13.9 0.2 0.1 13.1 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4463) DUF1465 PF07323.7 EGC29844.1 - 0.06 12.9 0.2 0.11 12.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1465) DUF1722 PF08349.6 EGC29844.1 - 0.081 12.7 0.9 0.12 12.2 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1722) Seryl_tRNA_N PF02403.17 EGC29844.1 - 0.23 11.5 4.4 0.89 9.5 0.6 2.2 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain ACCA PF03255.9 EGC29844.1 - 0.33 10.4 1.8 4.5 6.8 0.1 2.2 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit DivIC PF04977.10 EGC29844.1 - 0.46 9.9 3.0 0.33 10.4 0.8 1.7 2 0 0 2 2 2 0 Septum formation initiator DUF2360 PF10152.4 EGC29844.1 - 0.99 9.6 12.1 0.37 11.0 5.2 2.0 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) IL6 PF00489.12 EGC29844.1 - 7.4 6.1 9.7 5.3 6.6 2.6 2.6 2 1 0 2 2 2 0 Interleukin-6/G-CSF/MGF family TMF_DNA_bd PF12329.3 EGC29844.1 - 10 6.0 9.5 0.25 11.1 1.7 1.9 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding BAH PF01426.13 EGC29845.1 - 0.018 14.7 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 BAH domain Globin PF00042.17 EGC29845.1 - 0.045 14.0 0.3 0.15 12.4 0.1 1.8 2 0 0 2 2 2 0 Globin HSP20 PF00011.16 EGC29846.1 - 9.9e-19 67.0 0.2 3.4e-18 65.3 0.0 1.9 2 0 0 2 2 2 1 Hsp20/alpha crystallin family EF-hand_1 PF00036.27 EGC29849.1 - 6.3e-25 84.5 11.3 3e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC29849.1 - 1.1e-23 83.0 7.8 2e-11 43.8 1.3 2.3 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC29849.1 - 4.8e-20 69.5 6.8 4.7e-05 22.9 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC29849.1 - 5.7e-18 63.3 11.9 0.00058 19.0 0.1 4.8 4 1 1 5 5 5 4 EF hand EF-hand_8 PF13833.1 EGC29849.1 - 1.2e-12 47.2 16.8 0.0019 17.8 1.3 4.9 2 2 2 4 4 4 4 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC29849.1 - 1.5e-07 31.4 0.7 0.005 16.8 0.0 2.3 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGC29849.1 - 0.00014 21.5 7.0 0.45 10.2 0.3 3.7 1 1 3 4 4 4 3 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGC29849.1 - 0.0076 16.1 1.2 1 9.3 0.1 3.2 2 1 1 3 3 3 2 EF-hand domain DUF217 PF02697.9 EGC29849.1 - 0.017 15.3 1.6 2.6 8.3 0.0 2.9 3 0 0 3 3 3 0 Uncharacterized ACR, COG1753 TerB PF05099.8 EGC29849.1 - 0.1 12.3 0.0 1.4 8.6 0.0 2.2 2 0 0 2 2 2 0 Tellurite resistance protein TerB Glyco_hydro_85 PF03644.8 EGC29850.1 - 1.1e-87 294.0 11.0 1.8e-86 290.0 6.6 2.4 2 0 0 2 2 2 2 Glycosyl hydrolase family 85 GHL6 PF14871.1 EGC29850.1 - 0.054 13.5 0.2 4.6 7.2 0.1 3.2 2 1 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 FKBP_C PF00254.23 EGC29852.1 - 0.0047 16.9 0.0 0.0049 16.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase CHIPS PF11434.3 EGC29852.1 - 0.045 13.3 0.0 0.05 13.2 0.0 1.1 1 0 0 1 1 1 0 Chemotaxis-inhibiting protein CHIPS DUF2290 PF10053.4 EGC29852.1 - 0.06 12.6 0.0 0.067 12.5 0.0 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2290) gag-asp_proteas PF13975.1 EGC29854.1 - 0.0026 17.5 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGC29854.1 - 0.086 12.7 0.0 0.22 11.4 0.0 1.9 1 1 0 1 1 1 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGC29854.1 - 0.097 13.1 0.0 0.21 12.0 0.0 1.7 1 1 1 2 2 2 0 Aspartyl protease Tox-REase-2 PF15646.1 EGC29854.1 - 0.16 11.8 2.8 1 9.2 0.8 2.2 1 1 1 2 2 2 0 Restriction endonuclease fold toxin 2 DUF2372 PF10178.4 EGC29855.1 - 3.8e-22 78.2 0.9 4.5e-22 78.0 0.1 1.5 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2372) chaperone_DMP PF10448.4 EGC29855.1 - 0.23 11.3 3.6 0.44 10.4 2.5 1.4 1 1 0 1 1 1 0 20S proteasome chaperone Mito_carr PF00153.22 EGC29856.1 - 2.8e-65 216.0 1.8 3e-27 94.1 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Gelsolin PF00626.17 EGC29857.1 - 1.2e-65 217.1 20.4 5.1e-18 64.5 0.0 8.4 8 0 0 8 8 8 7 Gelsolin repeat LRR_4 PF12799.2 EGC29857.1 - 1.3e-20 72.5 72.4 3.8e-06 26.3 2.5 7.6 4 1 5 10 10 10 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC29857.1 - 1.6e-19 69.4 45.6 7.5e-06 25.6 8.1 5.2 3 1 3 6 6 6 6 Leucine rich repeat VHP PF02209.14 EGC29857.1 - 1.1e-08 34.6 5.7 3.7e-08 32.9 4.0 2.1 1 0 0 1 1 1 1 Villin headpiece domain LRR_1 PF00560.28 EGC29857.1 - 1.1e-08 33.8 53.0 0.29 11.3 0.3 11.3 11 0 0 11 11 11 6 Leucine Rich Repeat LRR_7 PF13504.1 EGC29857.1 - 5.5e-06 25.7 38.2 1.8 9.1 0.1 10.6 10 0 0 10 10 10 4 Leucine rich repeat LRR_6 PF13516.1 EGC29857.1 - 0.02 14.9 0.0 0.02 14.9 0.0 10.2 10 1 1 11 11 11 0 Leucine Rich repeat Tox-WTIP PF15654.1 EGC29858.1 - 0.03 13.9 0.1 0.088 12.4 0.1 1.8 1 0 0 1 1 1 0 Toxin with a conserved tryptophan and TIP tripeptide motif Pex14_N PF04695.8 EGC29859.1 - 0.029 14.4 4.5 2.2 8.3 0.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Tetraspannin PF00335.15 EGC29859.1 - 1.9 7.7 4.9 3.9 6.7 3.4 1.5 1 1 0 1 1 1 0 Tetraspanin family Pacs-1 PF10254.4 EGC29860.1 - 1.7e-20 73.0 10.5 1.7e-20 73.0 7.3 2.9 1 1 0 1 1 1 1 PACS-1 cytosolic sorting protein adh_short PF00106.20 EGC29861.1 - 5.8e-34 117.4 0.0 7.3e-34 117.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC29861.1 - 9.5e-16 57.9 0.0 1.4e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC29861.1 - 3.8e-13 49.7 0.0 4.7e-13 49.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGC29861.1 - 0.00057 19.3 0.0 0.00087 18.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Eno-Rase_NADH_b PF12242.3 EGC29861.1 - 0.027 14.2 0.0 0.064 13.0 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Saccharop_dh PF03435.13 EGC29861.1 - 0.042 12.8 0.1 0.061 12.2 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_10 PF13460.1 EGC29861.1 - 0.071 13.1 0.0 0.19 11.7 0.0 2.0 1 1 0 1 1 1 0 NADH(P)-binding Med13_C PF06333.7 EGC29862.1 - 2.5e-13 49.3 20.0 2.5e-13 49.3 13.8 8.4 6 2 1 7 7 7 1 Mediator complex subunit 13 C-terminal Mucin PF01456.12 EGC29863.1 - 0.15 11.8 22.6 0.24 11.1 15.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EGC29863.1 - 6.7 4.3 28.2 9.1 3.8 19.5 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein ResIII PF04851.10 EGC29866.1 - 3.1 7.5 10.6 5.4 6.8 6.6 2.0 1 1 1 2 2 2 0 Type III restriction enzyme, res subunit DAGK_prokar PF01219.14 EGC29867.1 - 0.27 10.8 1.8 0.58 9.7 1.3 1.5 1 0 0 1 1 1 0 Prokaryotic diacylglycerol kinase DUF3439 PF11921.3 EGC29867.1 - 2 8.1 9.8 6.2 6.6 6.8 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Gelsolin PF00626.17 EGC29868.1 - 2.3e-19 68.8 15.6 1.6e-06 27.6 0.0 6.0 6 0 0 6 6 6 5 Gelsolin repeat VWA_2 PF13519.1 EGC29869.1 - 1.6e-05 25.0 0.0 3.6e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain MMR_HSR1 PF01926.18 EGC29869.1 - 3e-05 23.9 0.7 3e-05 23.9 0.5 3.3 4 0 0 4 4 4 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC29869.1 - 0.011 15.5 4.1 1.4 8.7 0.0 3.2 2 1 1 3 3 3 0 Dynamin family VWA_2 PF13519.1 EGC29870.1 - 5.9e-06 26.4 0.0 8.7e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain HATPase_c PF02518.21 EGC29870.1 - 0.051 13.3 0.1 0.14 11.9 0.0 1.8 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DDE_Tnp_4 PF13359.1 EGC29872.1 - 3.5e-08 33.2 0.3 2.4e-07 30.4 0.1 2.0 1 1 1 2 2 2 1 DDE superfamily endonuclease DUF3212 PF11486.3 EGC29872.1 - 0.0049 16.6 0.0 0.011 15.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3212) Herpes_U15 PF05613.6 EGC29872.1 - 0.11 12.8 0.4 0.24 11.7 0.3 1.5 1 0 0 1 1 1 0 Human herpesvirus U15 protein Complex1_LYR PF05347.10 EGC29873.1 - 0.0055 16.4 1.0 0.035 13.8 0.2 2.1 2 0 0 2 2 2 1 Complex 1 protein (LYR family) DUF2573 PF10835.3 EGC29873.1 - 0.04 13.9 0.0 0.074 13.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2573) RabGAP-TBC PF00566.13 EGC29874.1 - 1.7e-19 70.1 1.7 2.4e-19 69.6 1.2 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain EGF_CA PF07645.10 EGC29875.1 - 6.5e-11 42.0 25.4 6.1e-08 32.5 7.1 7.7 5 2 2 7 7 7 2 Calcium-binding EGF domain EGF PF00008.22 EGC29875.1 - 1.5e-05 24.8 78.4 0.14 12.1 4.6 7.3 6 1 0 6 6 6 5 EGF-like domain EGF_2 PF07974.8 EGC29875.1 - 3.7e-05 23.8 14.5 3.7e-05 23.8 10.1 7.0 5 1 0 6 6 6 3 EGF-like domain TIG PF01833.19 EGC29875.1 - 5.2e-05 23.1 4.3 6.6e-05 22.8 0.9 2.9 2 0 0 2 2 2 1 IPT/TIG domain cEGF PF12662.2 EGC29875.1 - 0.00077 19.0 2.8 0.00077 19.0 1.9 6.6 5 1 1 6 6 6 3 Complement Clr-like EGF-like EGF_3 PF12947.2 EGC29875.1 - 0.0018 18.1 22.1 0.0043 16.9 6.9 7.1 5 1 1 6 6 6 3 EGF domain hEGF PF12661.2 EGC29875.1 - 0.09 12.9 35.3 0.086 12.9 2.3 6.6 6 0 0 6 6 6 0 Human growth factor-like EGF EB PF01683.13 EGC29875.1 - 1 9.5 88.7 0.039 14.0 7.5 7.5 4 3 2 7 7 7 0 EB module DDE_Tnp_4 PF13359.1 EGC29876.1 - 1.1e-14 54.3 2.0 1.8e-14 53.6 0.0 2.4 2 1 0 2 2 2 1 DDE superfamily endonuclease Rpr2 PF04032.11 EGC29876.1 - 2.3e-14 53.0 4.8 2.3e-14 53.0 3.3 2.7 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain FAM176 PF14851.1 EGC29876.1 - 0.0032 17.1 2.7 0.0032 17.1 1.9 3.6 4 0 0 4 4 4 1 FAM176 family DUF605 PF04652.11 EGC29876.1 - 0.024 14.0 19.0 0.042 13.2 6.7 2.2 2 0 0 2 2 2 0 Vta1 like TRAP_alpha PF03896.11 EGC29876.1 - 0.088 11.7 11.9 0.013 14.5 4.9 1.9 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit DUF4366 PF14283.1 EGC29876.1 - 0.62 9.4 16.2 0.073 12.4 7.7 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4366) RNA_pol_3_Rpc31 PF11705.3 EGC29876.1 - 1.4 8.7 29.2 3.4 7.5 0.1 3.2 3 0 0 3 3 3 0 DNA-directed RNA polymerase III subunit Rpc31 eIF-3c_N PF05470.7 EGC29876.1 - 8.7 4.2 15.5 0.85 7.6 6.8 2.0 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Chromo PF00385.19 EGC29879.1 - 1.9e-07 30.6 0.1 2.5e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC29879.1 - 0.088 12.5 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-CCHC PF00098.18 EGC29880.1 - 7.3e-05 22.4 1.0 0.00012 21.7 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle tRNA_anti-like PF12869.2 EGC29880.1 - 0.062 12.7 1.5 0.093 12.2 0.2 1.9 2 0 0 2 2 2 0 tRNA_anti-like Phi-29_GP4 PF05464.6 EGC29880.1 - 0.34 10.8 7.2 0.045 13.6 0.5 2.8 2 1 1 3 3 3 0 Phi-29-like late genes activator (early protein GP4) Microtub_assoc PF07989.6 EGC29880.1 - 3.8 7.4 21.1 2.2 8.1 0.5 4.5 2 1 2 4 4 4 0 Microtubule associated Mannosyl_trans PF05007.8 EGC29881.1 - 7.4e-81 271.6 30.4 7.4e-81 271.6 21.1 1.5 2 0 0 2 2 2 1 Mannosyltransferase (PIG-M) PIG-U PF06728.8 EGC29881.1 - 2.6e-12 46.2 31.4 4.2e-11 42.3 21.0 2.1 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF2029 PF09594.5 EGC29881.1 - 0.0021 17.6 14.0 0.0021 17.6 9.7 3.1 2 1 1 3 3 3 1 Protein of unknown function (DUF2029) SAPS PF04499.10 EGC29882.1 - 2.8e-07 29.5 0.3 2.8e-07 29.5 0.2 7.2 3 3 3 6 6 6 3 SIT4 phosphatase-associated protein DUF3439 PF11921.3 EGC29882.1 - 0.13 11.9 23.2 0.39 10.4 16.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC29882.1 - 0.56 9.9 31.8 0.64 9.7 20.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein HEAT PF02985.17 EGC29883.1 - 4.7e-06 26.2 5.4 0.18 11.9 0.0 6.2 8 0 0 8 8 8 2 HEAT repeat HEAT_2 PF13646.1 EGC29883.1 - 0.0003 20.9 0.0 2.3 8.5 0.0 4.9 3 1 1 4 4 4 1 HEAT repeats HEAT_EZ PF13513.1 EGC29883.1 - 0.0043 17.4 0.0 19 5.9 0.0 5.3 6 0 0 6 6 6 1 HEAT-like repeat Mito_carr PF00153.22 EGC29884.1 - 6.3e-60 198.8 7.4 2.7e-20 71.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Wzz PF02706.10 EGC29884.1 - 0.0098 15.7 0.2 0.81 9.4 0.1 2.5 2 0 0 2 2 2 2 Chain length determinant protein DUF92 PF01940.11 EGC29884.1 - 0.059 12.5 2.1 0.066 12.3 0.0 2.1 3 0 0 3 3 3 0 Integral membrane protein DUF92 Acyl_transf_1 PF00698.16 EGC29885.1 - 3.3e-48 164.6 0.0 6.5e-48 163.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC29885.1 - 5e-32 110.2 0.0 1e-31 109.2 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EGC29885.1 - 1.7e-24 86.7 0.3 3.6e-24 85.6 0.1 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.7 EGC29885.1 - 1.8e-23 82.8 3.0 4.9e-22 78.2 0.0 4.1 3 0 0 3 3 3 1 Methyltransferase domain KR PF08659.5 EGC29885.1 - 1.6e-21 76.7 0.0 2.9e-21 75.9 0.0 1.4 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC29885.1 - 2.3e-19 69.6 0.0 3.6e-19 69.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC29885.1 - 4.4e-14 52.7 0.0 1.1e-13 51.5 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC29885.1 - 1.8e-07 31.0 0.0 5.1e-07 29.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC29885.1 - 1.1e-06 29.5 0.0 2.3e-06 28.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EGC29885.1 - 2.8e-06 27.7 0.0 1.3e-05 25.5 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGC29885.1 - 4.1e-06 26.5 0.1 9.1e-06 25.3 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EGC29885.1 - 7.2e-06 26.5 0.0 4.2e-05 24.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC29885.1 - 2e-05 24.7 0.3 5.5e-05 23.3 0.2 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EGC29885.1 - 0.00014 21.4 4.6 0.0006 19.4 0.0 4.3 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 EGC29885.1 - 0.00018 20.5 0.1 0.00035 19.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Arf PF00025.16 EGC29886.1 - 2.1e-78 261.5 0.1 2.5e-78 261.2 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC29886.1 - 4.2e-15 55.4 0.0 5e-15 55.1 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC29886.1 - 5.3e-13 48.4 2.8 2e-10 39.9 0.3 2.4 2 1 1 3 3 3 2 G-protein alpha subunit Ras PF00071.17 EGC29886.1 - 6.8e-13 48.3 0.0 7.5e-13 48.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC29886.1 - 2.4e-12 46.5 0.0 2.8e-12 46.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC29886.1 - 2.8e-08 34.2 0.0 4.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC29886.1 - 8.2e-06 25.7 0.0 1.1e-05 25.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC29886.1 - 0.0035 16.8 0.3 0.02 14.3 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain 6PF2K PF01591.13 EGC29886.1 - 0.0095 15.0 0.6 0.028 13.5 0.1 1.7 1 1 0 2 2 2 1 6-phosphofructo-2-kinase AAA_33 PF13671.1 EGC29886.1 - 0.072 12.9 0.1 0.14 12.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain PAS_8 PF13188.1 EGC29886.1 - 0.1 12.4 0.0 0.22 11.4 0.0 1.5 1 0 0 1 1 1 0 PAS domain UPF1_Zn_bind PF09416.5 EGC29887.1 - 1.4e-65 219.5 9.2 1.4e-65 219.5 6.3 2.2 2 0 0 2 2 2 1 RNA helicase (UPF2 interacting domain) UAA PF08449.6 EGC29888.1 - 5.1e-74 248.9 14.0 5.9e-74 248.7 9.7 1.0 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGC29888.1 - 2.1e-09 37.5 15.9 2e-06 27.8 4.6 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EGC29888.1 - 1.5e-05 24.6 14.0 8.8e-05 22.2 5.5 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EGC29888.1 - 2.5e-05 24.4 10.0 0.0053 16.9 0.1 2.2 2 0 0 2 2 2 2 Multidrug resistance efflux transporter DUF3188 PF11384.3 EGC29888.1 - 1.9 8.1 5.9 22 4.7 0.2 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3188) DUF3430 PF11912.3 EGC29889.1 - 7.5e-20 71.6 35.0 8.3e-20 71.5 24.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Pkinase_Tyr PF07714.12 EGC29890.1 - 4e-59 199.7 0.0 6.2e-59 199.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC29890.1 - 8.2e-57 192.3 0.0 1.4e-56 191.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EGC29890.1 - 1.7e-09 37.3 0.1 1.3e-08 34.5 0.0 2.3 2 0 0 2 2 2 1 SH2 domain APH PF01636.18 EGC29890.1 - 0.0024 17.6 0.1 0.034 13.8 0.1 2.7 3 1 1 4 4 4 1 Phosphotransferase enzyme family Cbl_N3 PF02762.9 EGC29890.1 - 0.035 13.7 0.0 0.099 12.2 0.0 1.8 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Lzipper-MIP1 PF14389.1 EGC29890.1 - 0.045 13.8 7.7 0.095 12.8 5.3 1.5 1 0 0 1 1 1 0 Leucine-zipper of ternary complex factor MIP1 XRN_N PF03159.13 EGC29891.1 - 4.7e-20 71.9 0.1 4.7e-20 71.9 0.1 2.0 2 0 0 2 2 2 1 XRN 5'-3' exonuclease N-terminus Complex1_51K PF01512.12 EGC29892.1 - 2.2e-48 163.8 0.0 4.2e-48 162.9 0.0 1.5 1 0 0 1 1 1 1 Respiratory-chain NADH dehydrogenase 51 Kd subunit NADH_4Fe-4S PF10589.4 EGC29892.1 - 1.1e-17 62.8 1.4 1.3e-17 62.6 0.0 1.8 2 0 0 2 2 2 1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region SLBB PF10531.4 EGC29892.1 - 2.7e-09 36.7 0.3 1.7e-08 34.1 0.0 2.5 3 0 0 3 3 3 1 SLBB domain Myb_DNA-binding PF00249.26 EGC29893.1 - 1.5e-31 108.2 1.2 4.6e-15 55.4 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC29893.1 - 2e-25 88.6 0.8 2.1e-15 56.5 0.1 3.5 2 1 1 3 3 3 2 Myb-like DNA-binding domain CBM49 PF09478.5 EGC29895.1 - 1.2e-14 54.1 0.1 1.7e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC29895.1 - 0.022 14.7 2.6 0.035 14.0 0.6 2.1 2 0 0 2 2 2 0 DIM protein Dala_Dala_lig_N PF01820.16 EGC29897.1 - 1.1 9.6 4.5 0.28 11.4 0.3 2.0 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus FNIP PF05725.7 EGC29898.1 - 1.4e-182 591.4 89.2 1.1e-17 63.6 0.4 15.2 12 3 1 14 14 14 14 FNIP Repeat NNMT_PNMT_TEMT PF01234.12 EGC29898.1 - 0.13 11.2 0.7 2.8 6.8 0.0 2.9 3 0 0 3 3 3 0 NNMT/PNMT/TEMT family CBM49 PF09478.5 EGC29899.1 - 1.2e-14 54.1 0.1 1.7e-14 53.6 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC29899.1 - 0.022 14.7 2.6 0.035 14.0 0.6 2.1 2 0 0 2 2 2 0 DIM protein CH PF00307.26 EGC29900.1 - 3e-38 130.1 12.6 7.6e-12 45.2 0.1 6.8 6 1 0 6 6 6 5 Calponin homology (CH) domain PH PF00169.24 EGC29900.1 - 5.6e-12 45.7 0.9 2.4e-11 43.7 0.0 2.6 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC29900.1 - 2.7e-07 30.8 0.1 2.7e-07 30.8 0.1 4.0 3 1 1 4 4 4 1 Pleckstrin homology domain Glyco_transf_5 PF08323.6 EGC29901.1 - 5.3e-37 127.6 0.0 1.1e-36 126.5 0.0 1.6 1 0 0 1 1 1 1 Starch synthase catalytic domain Glycos_transf_1 PF00534.15 EGC29901.1 - 9.7e-14 51.1 0.0 3.1e-13 49.5 0.0 1.9 1 0 0 1 1 1 1 Glycosyl transferases group 1 Alpha-amylase PF00128.19 EGC29901.1 - 4.5e-05 22.9 0.0 0.0014 18.0 0.0 3.0 2 1 0 2 2 2 1 Alpha amylase, catalytic domain Glyco_trans_1_4 PF13692.1 EGC29901.1 - 0.024 14.7 0.0 0.069 13.3 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGC29901.1 - 0.071 13.2 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGC29901.1 - 0.14 12.4 0.0 0.41 10.9 0.0 1.8 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF3430 PF11912.3 EGC29903.1 - 1.8e-12 47.5 25.3 2.2e-12 47.2 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC29903.1 - 0.063 13.3 0.6 0.063 13.3 0.4 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) Ribosomal_S10 PF00338.17 EGC29903.1 - 0.14 12.0 0.0 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal protein S10p/S20e Ibs_toxin PF13956.1 EGC29903.1 - 1.9 8.3 5.0 3.5 7.5 3.5 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system FGase PF05013.7 EGC29904.1 - 0.062 13.1 1.8 5 6.9 0.6 2.9 3 1 0 3 3 3 0 N-formylglutamate amidohydrolase Cyto_heme_lyase PF01265.12 EGC29906.1 - 3.1e-75 253.1 0.6 3.6e-75 252.9 0.4 1.0 1 0 0 1 1 1 1 Cytochrome c/c1 heme lyase SNF5 PF04855.7 EGC29906.1 - 0.0057 16.1 0.5 0.0093 15.4 0.3 1.3 1 0 0 1 1 1 1 SNF5 / SMARCB1 / INI1 D123 PF07065.9 EGC29907.1 - 1.6e-87 293.3 14.8 1e-86 290.7 10.2 1.9 1 1 0 1 1 1 1 D123 Sigma70_ner PF04546.8 EGC29907.1 - 0.0015 18.2 4.6 0.0015 18.2 3.2 1.9 2 0 0 2 2 2 1 Sigma-70, non-essential region DUF4343 PF14243.1 EGC29907.1 - 0.011 15.5 0.0 0.02 14.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4343) Sporozoite_P67 PF05642.6 EGC29907.1 - 0.51 8.1 5.5 0.86 7.3 3.8 1.3 1 0 0 1 1 1 0 Sporozoite P67 surface antigen FAM176 PF14851.1 EGC29907.1 - 0.76 9.4 3.5 1.9 8.1 2.4 1.6 1 0 0 1 1 1 0 FAM176 family Nucleoplasmin PF03066.10 EGC29907.1 - 0.9 9.0 13.3 0.13 11.7 6.1 1.9 2 0 0 2 2 2 0 Nucleoplasmin NOA36 PF06524.7 EGC29907.1 - 2.3 7.3 7.1 3.8 6.6 4.9 1.3 1 0 0 1 1 1 0 NOA36 protein PBP1_TM PF14812.1 EGC29907.1 - 2.7 8.3 13.3 0.29 11.4 5.7 2.0 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RasGAP PF00616.14 EGC29908.1 - 8.6e-41 139.7 8.0 8.6e-41 139.7 5.6 3.9 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CH PF00307.26 EGC29908.1 - 1.1e-31 109.0 0.6 3.6e-20 72.0 0.0 3.1 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC29908.1 - 0.0012 18.4 0.2 0.019 14.6 0.1 2.7 2 0 0 2 2 2 1 CAMSAP CH domain DUF3899 PF13038.1 EGC29908.1 - 1.5 9.0 0.0 1.5 9.0 0.0 3.6 2 1 2 4 4 4 0 Domain of unknown function (DUF3899) Alpha_L_fucos PF01120.12 EGC29909.1 - 1.6e-104 349.5 9.7 2.4e-104 348.9 6.8 1.3 1 0 0 1 1 1 1 Alpha-L-fucosidase CCDC142 PF14923.1 EGC29909.1 - 0.043 12.1 0.2 0.062 11.6 0.1 1.1 1 0 0 1 1 1 0 Coiled-coil protein 142 Rib_5-P_isom_A PF06026.9 EGC29910.1 - 3.3e-55 186.0 0.0 4.1e-55 185.7 0.0 1.1 1 0 0 1 1 1 1 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) Sugar-bind PF04198.8 EGC29910.1 - 0.0014 17.5 0.0 0.0021 17.0 0.0 1.2 1 0 0 1 1 1 1 Putative sugar-binding domain DeoRC PF00455.17 EGC29910.1 - 0.0052 16.4 0.0 0.0097 15.5 0.0 1.4 1 0 0 1 1 1 1 DeoR C terminal sensor domain Amidase PF01425.16 EGC29911.1 - 2e-94 316.9 0.0 2.7e-94 316.5 0.0 1.1 1 0 0 1 1 1 1 Amidase Ssu72 PF04722.8 EGC29912.1 - 2.2e-75 252.2 0.2 2.6e-75 252.0 0.1 1.0 1 0 0 1 1 1 1 Ssu72-like protein LMWPc PF01451.16 EGC29912.1 - 0.01 16.1 0.2 3.4 7.9 0.0 2.2 2 0 0 2 2 2 0 Low molecular weight phosphotyrosine protein phosphatase DUF904 PF06005.7 EGC29912.1 - 0.55 10.5 3.1 26 5.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF904) Neur_chan_memb PF02932.11 EGC29913.1 - 0.51 10.1 6.8 0.059 13.2 1.4 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region zf-RING_2 PF13639.1 EGC29915.1 - 7.6e-11 41.6 9.4 1.3e-10 40.9 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC29915.1 - 3.5e-08 32.9 7.4 5.4e-08 32.3 5.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC29915.1 - 1.3e-07 31.1 13.1 2.6e-07 30.1 9.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29915.1 - 3.6e-07 30.2 7.5 9e-07 28.9 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC29915.1 - 1.4e-05 24.9 11.2 2.3e-05 24.2 7.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29915.1 - 1.5e-05 24.6 9.8 2.6e-05 23.8 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29915.1 - 0.0043 16.9 8.2 0.0096 15.7 5.4 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC29915.1 - 0.007 15.9 9.6 0.013 15.0 6.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC29915.1 - 0.03 14.1 3.4 0.077 12.8 2.4 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger IBR PF01485.16 EGC29915.1 - 0.045 13.6 11.1 0.12 12.2 7.7 1.8 1 0 0 1 1 1 0 IBR domain Prok-RING_4 PF14447.1 EGC29915.1 - 0.065 12.7 3.8 0.17 11.4 2.6 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGC29915.1 - 0.22 11.3 1.8 0.41 10.4 1.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein C1_4 PF07975.7 EGC29915.1 - 0.9 9.5 10.6 3.9 7.5 7.3 2.2 1 1 0 1 1 1 0 TFIIH C1-like domain Sad1_UNC PF07738.8 EGC29917.1 - 1.2e-31 109.2 1.1 1.2e-31 109.2 0.8 2.9 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Dickkopf_N PF04706.7 EGC29918.1 - 0.0016 18.5 10.3 0.0016 18.5 7.1 5.4 4 2 1 5 5 5 1 Dickkopf N-terminal cysteine-rich region EB PF01683.13 EGC29918.1 - 0.27 11.3 81.6 0.047 13.7 3.4 7.7 1 1 7 8 8 8 0 EB module Glucos_trans_II PF14264.1 EGC29919.1 - 0.002 17.2 2.5 0.002 17.2 1.7 2.7 3 0 0 3 3 3 1 Glucosyl transferase GtrII 7TM_GPCR_Str PF10326.4 EGC29919.1 - 0.0042 16.2 9.2 0.0042 16.2 6.4 2.3 1 1 1 2 2 2 1 Serpentine type 7TM GPCR chemoreceptor Str MARVEL PF01284.18 EGC29919.1 - 0.022 14.5 2.3 0.11 12.2 0.5 2.3 2 1 0 2 2 2 0 Membrane-associating domain Internalin_N PF12354.3 EGC29919.1 - 0.075 12.6 17.4 0.077 12.6 0.0 4.4 5 0 0 5 5 5 0 Bacterial adhesion/invasion protein N terminal Pox_A14 PF05767.7 EGC29919.1 - 0.082 12.8 11.7 0.026 14.4 2.7 2.6 3 0 0 3 3 2 0 Poxvirus virion envelope protein A14 DUF3733 PF12534.3 EGC29919.1 - 0.09 12.0 1.2 0.34 10.2 0.5 2.2 2 0 0 2 2 2 0 Leucine-rich repeat containing protein 8 PMP22_Claudin PF00822.15 EGC29919.1 - 0.11 12.2 4.2 0.062 12.9 0.8 2.1 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family DUF1772 PF08592.6 EGC29919.1 - 0.12 12.1 1.1 0.13 11.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) DUF2628 PF10947.3 EGC29919.1 - 0.21 11.3 3.8 0.98 9.2 0.0 2.6 3 0 0 3 3 2 0 Protein of unknown function (DUF2628) MSC PF09402.5 EGC29919.1 - 0.33 9.6 5.6 0.2 10.2 2.4 1.8 1 1 1 2 2 2 0 Man1-Src1p-C-terminal domain DUF4013 PF13197.1 EGC29919.1 - 1.2 8.4 10.3 0.079 12.2 0.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) PIG-F PF06699.6 EGC29919.1 - 1.2 9.0 6.0 0.17 11.8 0.7 2.1 3 0 0 3 3 3 0 GPI biosynthesis protein family Pig-F p450 PF00067.17 EGC29920.1 - 4.5e-73 246.3 0.1 5.6e-73 246.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 AAA_35 PF14516.1 EGC29921.1 - 0.00022 19.9 1.8 0.00033 19.4 1.2 1.3 1 1 0 1 1 1 1 AAA-like domain Arch_ATPase PF01637.13 EGC29921.1 - 0.026 14.2 0.0 0.042 13.5 0.0 1.5 1 0 0 1 1 1 0 Archaeal ATPase Pro_isomerase PF00160.16 EGC29923.1 - 5.8e-47 159.7 0.2 6.7e-47 159.5 0.2 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD FAA_hydrolase PF01557.13 EGC29924.1 - 2e-51 174.5 0.0 2.7e-51 174.0 0.0 1.2 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family FAA_hydrolase_N PF09298.6 EGC29924.1 - 1.5e-30 105.3 0.0 6.4e-30 103.2 0.0 1.9 2 0 0 2 2 2 1 Fumarylacetoacetase N-terminal DUF4604 PF15377.1 EGC29925.1 - 0.063 13.4 36.1 0.23 11.6 25.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4604) DUF572 PF04502.8 EGC29925.1 - 0.39 9.8 25.4 0.45 9.6 17.6 1.2 1 0 0 1 1 1 0 Family of unknown function (DUF572) SOBP PF15279.1 EGC29925.1 - 2.2 8.6 9.6 2.9 8.2 6.7 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Colicin-DNase PF12639.2 EGC29925.1 - 4.7 7.4 18.4 0.49 10.6 2.7 2.5 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin RhoGEF PF00621.15 EGC29927.1 - 8.3e-52 175.6 6.2 3e-51 173.8 4.3 2.1 1 0 0 1 1 1 1 RhoGEF domain VHP PF02209.14 EGC29927.1 - 4.9e-12 45.3 3.9 1.1e-11 44.1 2.7 1.6 1 0 0 1 1 1 1 Villin headpiece domain CH PF00307.26 EGC29927.1 - 3.3e-09 36.7 1.3 1.6e-08 34.5 0.2 2.6 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.6 EGC29927.1 - 1.1e-05 25.3 0.1 3.9e-05 23.6 0.1 2.0 1 0 0 1 1 1 1 CDC24 Calponin Cob_adeno_trans PF01923.13 EGC29928.1 - 0.052 13.3 0.9 0.12 12.1 0.6 1.6 1 0 0 1 1 1 0 Cobalamin adenosyltransferase Kelch_3 PF13415.1 EGC29929.1 - 8.1e-44 146.8 10.1 8.1e-10 38.5 0.0 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC29929.1 - 1.2e-40 136.9 10.8 7.9e-09 35.1 0.1 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC29929.1 - 4.3e-36 122.2 6.4 2.3e-08 33.4 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC29929.1 - 1.9e-35 119.5 9.3 2.9e-10 39.8 0.0 6.6 4 1 2 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC29929.1 - 9.4e-31 105.2 0.4 6.8e-05 22.7 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC29929.1 - 2.6e-23 80.8 12.8 1.8e-05 24.3 0.0 6.4 6 0 0 6 6 6 5 Kelch motif SAM_2 PF07647.12 EGC29929.1 - 2.8e-05 23.8 0.2 5.9e-05 22.8 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC29929.1 - 0.00024 21.1 0.2 0.00049 20.2 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) TraG-D_C PF12696.2 EGC29929.1 - 2.1 8.2 5.5 0.47 10.3 0.2 2.1 2 0 0 2 2 2 0 TraM recognition site of TraD and TraG DNA_pol_A PF00476.15 EGC29930.1 - 6.9e-61 205.9 0.0 3.6e-60 203.6 0.0 2.1 2 0 0 2 2 2 1 DNA polymerase family A 5_3_exonuc_N PF02739.11 EGC29930.1 - 3.1e-37 127.5 0.2 1e-36 125.8 0.0 2.0 2 0 0 2 2 2 1 5'-3' exonuclease, N-terminal resolvase-like domain 5_3_exonuc PF01367.15 EGC29930.1 - 4.1e-24 84.7 0.0 2.4e-23 82.2 0.0 2.5 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold DNA_pol_A_exo1 PF01612.15 EGC29930.1 - 6e-14 51.9 0.1 2.6e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 3'-5' exonuclease HHH_2 PF12826.2 EGC29930.1 - 0.017 14.9 0.0 0.15 11.9 0.0 2.3 2 0 0 2 2 2 0 Helix-hairpin-helix motif Lipin_N PF04571.9 EGC29931.1 - 3.1e-10 39.6 0.0 4.3e-10 39.2 0.0 1.2 1 0 0 1 1 1 1 lipin, N-terminal conserved region GATA PF00320.22 EGC29933.1 - 4.2e-06 26.0 1.9 4.2e-06 26.0 1.3 1.7 2 0 0 2 2 2 1 GATA zinc finger zf-C3HC4_3 PF13920.1 EGC29933.1 - 0.074 12.7 2.1 5.4 6.7 0.1 2.8 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF837 PF05769.6 EGC29935.1 - 0.0026 17.3 4.3 0.0036 16.8 3.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF837) LTV PF04180.9 EGC29935.1 - 0.0069 15.9 1.8 0.0082 15.6 1.3 1.0 1 0 0 1 1 1 1 Low temperature viability protein OrfB_Zn_ribbon PF07282.6 EGC29937.1 - 0.08 12.6 0.1 0.11 12.1 0.0 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain Pkinase PF00069.20 EGC29938.1 - 0.014 14.5 0.4 0.055 12.5 0.4 1.7 1 1 1 2 2 2 0 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29938.1 - 0.066 12.2 0.2 0.91 8.5 0.2 1.9 1 1 1 2 2 2 0 Protein tyrosine kinase FNIP PF05725.7 EGC29940.1 - 3.8e-17 61.9 20.7 2.7e-09 36.8 1.6 5.8 4 2 0 4 4 4 3 FNIP Repeat Ribosomal_L21e PF01157.13 EGC29941.1 - 3.5e-38 129.3 2.0 4.9e-38 128.9 1.4 1.2 1 0 0 1 1 1 1 Ribosomal protein L21e Rogdi_lz PF10259.4 EGC29942.1 - 1.4e-09 37.4 3.2 3.3e-08 32.9 2.2 2.5 1 1 0 1 1 1 1 Rogdi leucine zipper containing protein RNA_pol_L_2 PF13656.1 EGC29943.1 - 1.1e-25 88.8 0.1 1.4e-25 88.4 0.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGC29943.1 - 2.2e-10 39.5 0.0 3.2e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ribosomal_S19e PF01090.14 EGC29946.1 - 5.1e-52 175.0 0.1 5.7e-52 174.8 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S19e tRNA_anti-codon PF01336.20 EGC29947.1 - 0.009 15.8 0.1 0.015 15.1 0.1 1.5 1 1 0 1 1 1 1 OB-fold nucleic acid binding domain FNIP PF05725.7 EGC29948.1 - 2.6e-51 171.3 77.0 3.4e-10 39.7 2.6 9.8 3 3 7 11 11 11 10 FNIP Repeat DUF1769 PF08588.5 EGC29948.1 - 3.2e-06 26.9 2.5 0.16 11.9 0.0 5.0 4 1 0 4 4 4 2 Protein of unknown function (DUF1769) Meth_synt_2 PF01717.13 EGC29949.1 - 2.3e-149 496.7 0.0 6e-140 465.8 0.0 2.4 3 0 0 3 3 3 2 Cobalamin-independent synthase, Catalytic domain Meth_synt_1 PF08267.7 EGC29949.1 - 1.8e-115 385.5 0.2 1.1e-98 330.3 0.1 3.8 3 1 0 3 3 3 3 Cobalamin-independent synthase, N-terminal domain Ribosomal_L5_C PF00673.16 EGC29950.1 - 7.5e-21 73.6 0.0 1.2e-20 73.0 0.0 1.3 1 0 0 1 1 1 1 ribosomal L5P family C-terminus Ribosomal_L5 PF00281.14 EGC29950.1 - 2.6e-20 71.9 0.1 2.3e-19 68.9 0.0 2.2 2 0 0 2 2 2 1 Ribosomal protein L5 RhoGAP PF00620.22 EGC29951.1 - 2.4e-44 150.6 1.0 2.4e-44 150.6 0.7 2.5 2 1 0 2 2 2 1 RhoGAP domain DUF3584 PF12128.3 EGC29951.1 - 1.1 6.5 41.0 0.91 6.7 17.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3584) DUF869 PF05911.6 EGC29951.1 - 2 6.5 52.0 0.17 10.1 30.5 2.2 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) RGS PF00615.14 EGC29952.1 - 2.4e-16 59.8 0.4 3.4e-13 49.7 0.1 2.6 2 0 0 2 2 2 2 Regulator of G protein signaling domain FmdE PF02663.9 EGC29952.1 - 0.075 12.9 0.0 0.2 11.5 0.0 1.8 1 0 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon CENP-P PF13096.1 EGC29953.1 - 0.001 18.4 0.5 0.0025 17.1 0.2 1.7 1 1 0 1 1 1 1 CENP-A-nucleosome distal (CAD) centromere subunit, CENP-P PLDc PF00614.17 EGC29954.1 - 3.6e-17 61.5 0.3 5.3e-08 32.4 0.0 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGC29954.1 - 3.9e-17 62.1 0.4 6e-09 35.7 0.1 3.2 2 0 0 2 2 2 2 PLD-like domain Response_reg PF00072.19 EGC29955.1 - 3.9e-41 139.5 0.2 4.3e-26 91.1 0.6 4.0 4 0 0 4 4 4 3 Response regulator receiver domain HATPase_c PF02518.21 EGC29955.1 - 3.4e-25 87.9 0.0 6.5e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGC29955.1 - 4.6e-16 58.5 0.2 1.6e-15 56.8 0.2 2.0 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EGC29955.1 - 3.6e-10 39.6 0.0 1.6e-09 37.5 0.0 2.2 2 0 0 2 2 2 1 PAS fold PAS_9 PF13426.1 EGC29955.1 - 4.4e-10 39.8 0.0 1.2e-09 38.5 0.0 1.8 1 0 0 1 1 1 1 PAS domain PAS_4 PF08448.5 EGC29955.1 - 5.5e-07 29.5 0.0 1.2e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 PAS fold REF PF05755.7 EGC29955.1 - 0.14 11.8 0.0 0.32 10.7 0.0 1.5 1 0 0 1 1 1 0 Rubber elongation factor protein (REF) E1_DerP2_DerF2 PF02221.10 EGC29956.1 - 1.4e-22 80.4 0.6 1.5e-22 80.2 0.4 1.0 1 0 0 1 1 1 1 ML domain Choline_kin_N PF04428.9 EGC29956.1 - 0.058 12.8 0.0 0.094 12.1 0.0 1.3 1 0 0 1 1 1 0 Choline kinase N terminus NDUF_B12 PF08122.7 EGC29957.1 - 0.00022 20.8 0.0 0.00025 20.7 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B12 subunit family Mucin PF01456.12 EGC29958.1 - 0.27 10.9 79.6 0.014 15.1 19.1 3.5 3 0 0 3 3 3 0 Mucin-like glycoprotein Usp PF00582.21 EGC29959.1 - 9.6e-24 84.1 0.0 1.1e-23 83.9 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family E1_DerP2_DerF2 PF02221.10 EGC29960.1 - 4e-20 72.4 0.1 4.5e-20 72.2 0.1 1.0 1 0 0 1 1 1 1 ML domain PI3K_1B_p101 PF10486.4 EGC29962.1 - 8.7e-06 23.6 0.3 8.7e-06 23.6 0.2 1.9 2 0 0 2 2 2 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit DDE_Tnp_IS240 PF13610.1 EGC29962.1 - 0.051 13.5 2.5 0.12 12.3 0.0 2.7 2 1 0 2 2 2 0 DDE domain Peptidase_C1 PF00112.18 EGC29963.1 - 2.6e-47 161.5 1.4 4.7e-47 160.7 1.0 1.3 1 0 0 1 1 1 1 Papain family cysteine protease CAP PF00188.21 EGC29963.1 - 3.7e-12 46.8 0.7 3.7e-12 46.8 0.5 2.6 3 1 1 4 4 4 1 Cysteine-rich secretory protein family Peptidase_C1_2 PF03051.10 EGC29963.1 - 0.022 13.2 0.5 0.46 8.9 0.0 2.1 2 0 0 2 2 2 0 Peptidase C1-like family Ras PF00071.17 EGC29964.1 - 1.1e-29 102.8 0.0 2.4e-29 101.8 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGC29964.1 - 3.2e-13 49.2 0.0 8e-13 47.9 0.0 1.7 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC29964.1 - 4e-13 49.8 0.0 1.3e-12 48.2 0.0 2.0 1 0 0 1 1 1 1 Miro-like protein LRR_6 PF13516.1 EGC29964.1 - 1.5e-06 27.6 35.0 0.0099 15.8 0.1 6.9 5 1 1 6 6 6 4 Leucine Rich repeat LRR_1 PF00560.28 EGC29964.1 - 0.26 11.4 27.6 2.3 8.5 0.6 7.1 5 0 0 5 5 5 0 Leucine Rich Repeat zf-RING_2 PF13639.1 EGC29966.1 - 2.7e-09 36.7 8.5 5.7e-09 35.6 5.9 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC29966.1 - 1.1e-07 31.3 10.5 3.3e-07 29.8 7.3 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC29966.1 - 1.9e-06 27.4 6.4 4.3e-06 26.2 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC29966.1 - 2.7e-06 27.3 4.8 8.5e-06 25.7 3.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC29966.1 - 7.5e-06 25.8 10.1 1.8e-05 24.6 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC29966.1 - 0.00061 19.6 8.2 0.0026 17.5 5.7 2.2 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC29966.1 - 0.0059 16.3 9.2 0.015 14.9 6.4 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC29966.1 - 0.017 14.9 0.9 0.037 13.8 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC29966.1 - 0.018 14.5 9.0 0.039 13.5 6.2 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC29966.1 - 0.049 13.3 5.1 0.18 11.5 3.6 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC29966.1 - 0.49 10.2 6.5 1.4 8.7 4.5 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Oxidored_q3 PF00499.15 EGC29966.1 - 0.65 9.7 4.8 1.7 8.4 3.3 1.8 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1888 PF08985.6 EGC29966.1 - 3.2 7.4 8.3 12 5.5 0.2 3.6 1 1 3 4 4 4 0 Domain of unknown function (DUF1888) Pkinase PF00069.20 EGC29967.1 - 4.6e-27 94.7 0.0 4.9e-27 94.7 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC29967.1 - 1.6e-17 63.4 0.0 1.8e-17 63.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC29967.1 - 0.0011 17.9 0.0 0.0014 17.6 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC29967.1 - 0.0047 16.6 0.0 0.0062 16.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC29967.1 - 0.0082 15.2 0.1 0.01 14.8 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC29967.1 - 0.037 13.3 0.1 0.047 13.0 0.1 1.1 1 0 0 1 1 1 0 RIO1 family Choline_kinase PF01633.15 EGC29967.1 - 0.17 11.4 1.5 0.21 11.1 1.0 1.1 1 0 0 1 1 1 0 Choline/ethanolamine kinase Rpr2 PF04032.11 EGC29968.1 - 0.00022 21.0 6.9 0.00022 21.0 4.8 2.4 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain Erf4 PF10256.4 EGC29971.1 - 9.2e-10 38.4 0.1 2.9e-09 36.8 0.0 1.8 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ABC2_membrane_2 PF12679.2 EGC29971.1 - 0.024 13.5 0.5 0.036 12.9 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Claudin_2 PF13903.1 EGC29971.1 - 0.031 13.9 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Trep_Strep PF09605.5 EGC29971.1 - 0.033 13.8 1.2 1.1 8.8 0.3 2.1 2 0 0 2 2 2 0 Hypothetical bacterial integral membrane protein (Trep_Strep) DUF4064 PF13273.1 EGC29971.1 - 0.075 13.1 1.9 0.17 12.0 1.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) Inhibitor_I29 PF08246.7 EGC29972.1 - 7.2e-13 48.6 8.5 1.7e-12 47.4 5.9 1.7 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) FAM165 PF14981.1 EGC29972.1 - 0.038 13.4 2.2 0.076 12.5 1.5 1.5 1 0 0 1 1 1 0 FAM165 family Methyltransf_31 PF13847.1 EGC29973.1 - 9.6e-18 64.2 0.0 2e-17 63.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC29973.1 - 6e-14 52.3 0.0 1e-13 51.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC29973.1 - 7.7e-11 41.5 0.0 2.4e-10 39.9 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGC29973.1 - 3.8e-09 36.4 0.0 1.7e-08 34.3 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29973.1 - 4.8e-09 36.5 0.0 1.1e-08 35.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29973.1 - 2.9e-08 34.2 0.0 6.3e-08 33.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC29973.1 - 2.9e-07 30.7 0.0 5.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC29973.1 - 0.00066 19.1 0.0 0.0018 17.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain DUF938 PF06080.7 EGC29973.1 - 0.00071 19.1 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Methyltransf_26 PF13659.1 EGC29973.1 - 0.0031 17.5 0.0 0.0066 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGC29973.1 - 0.01 15.3 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase FrhB_FdhB_C PF04432.8 EGC29973.1 - 0.013 14.8 0.0 0.022 14.1 0.0 1.3 1 0 0 1 1 1 0 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus Methyltransf_4 PF02390.12 EGC29973.1 - 0.018 14.1 0.0 0.073 12.1 0.0 1.9 2 0 0 2 2 2 0 Putative methyltransferase FmrO PF07091.6 EGC29973.1 - 0.12 11.3 0.0 8.8 5.2 0.0 2.1 2 0 0 2 2 2 0 Ribosomal RNA methyltransferase (FmrO) Methyltransf_20 PF12147.3 EGC29973.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase DUF3651 PF12371.3 EGC29974.1 - 1.6e-14 53.6 0.9 1.6e-14 53.6 0.6 5.9 5 0 0 5 5 5 2 Protein of unknown function (DUF3651) OTU PF02338.14 EGC29977.1 - 6.9e-13 49.2 0.0 6.9e-13 49.2 0.0 2.9 2 1 0 2 2 2 1 OTU-like cysteine protease LMBR1 PF04791.11 EGC29977.1 - 0.03 12.9 1.3 0.028 13.0 0.9 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Band_3_cyto PF07565.8 EGC29977.1 - 0.33 10.4 18.0 0.54 9.7 12.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 EGC29977.1 - 0.51 10.1 6.8 0.76 9.6 4.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PAT1 PF09770.4 EGC29977.1 - 0.96 7.6 49.8 1.2 7.3 34.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGC29977.1 - 1.1 7.3 68.0 1.4 7.0 47.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DDHD PF02862.12 EGC29978.1 - 1.7e-30 106.5 10.1 2e-30 106.3 5.7 2.1 2 1 0 2 2 2 1 DDHD domain DUF676 PF05057.9 EGC29978.1 - 8.8e-05 21.8 0.0 0.15 11.3 0.0 2.5 2 0 0 2 2 2 2 Putative serine esterase (DUF676) SID-1_RNA_chan PF13965.1 EGC29978.1 - 0.028 12.6 3.0 0.047 11.8 2.1 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF1373 PF07117.6 EGC29978.1 - 0.078 12.6 7.0 0.15 11.7 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1373) CAML PF14963.1 EGC29978.1 - 0.2 10.9 3.2 0.38 10.0 2.2 1.4 1 0 0 1 1 1 0 Calcium signal-modulating cyclophilin ligand DUF1675 PF07897.6 EGC29978.1 - 0.44 10.3 9.2 0.97 9.2 6.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) FAM176 PF14851.1 EGC29978.1 - 1.5 8.4 5.6 3.7 7.2 3.9 1.6 1 0 0 1 1 1 0 FAM176 family Sigma70_ner PF04546.8 EGC29978.1 - 5.2 6.6 9.4 1.7 8.2 3.8 2.0 2 0 0 2 2 2 0 Sigma-70, non-essential region ApoA-II PF04711.8 EGC29979.1 - 0.019 14.8 0.1 0.079 12.8 0.0 2.0 2 0 0 2 2 2 0 Apolipoprotein A-II (ApoA-II) Eapp_C PF10238.4 EGC29980.1 - 0.0048 16.7 15.8 0.18 11.6 2.7 2.3 2 0 0 2 2 2 2 E2F-associated phosphoprotein Neur_chan_memb PF02932.11 EGC29980.1 - 0.18 11.6 1.9 0.3 10.9 1.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region POX PF07526.6 EGC29980.1 - 0.23 11.6 5.9 2.1 8.5 0.1 2.8 3 0 0 3 3 3 0 Associated with HOX Secretin_N_2 PF07655.8 EGC29980.1 - 2.1 8.7 32.0 3.3 8.1 11.6 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain Apc15p PF05841.6 EGC29980.1 - 8.3 7.1 18.8 10 6.8 3.6 2.5 2 0 0 2 2 2 0 Apc15p protein RasGEF PF00617.14 EGC29981.1 - 1.3e-45 155.4 4.0 1.3e-45 155.4 2.8 3.2 3 1 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 EGC29981.1 - 1.2e-20 73.5 0.6 1.2e-20 73.5 0.4 4.2 3 0 0 3 3 3 1 RasGEF N-terminal motif zf-B_box PF00643.19 EGC29981.1 - 3.3e-11 42.8 3.5 3.3e-11 42.8 2.5 2.6 2 1 0 2 2 2 1 B-box zinc finger zf-C3HC4 PF00097.20 EGC29981.1 - 7.1e-07 28.7 9.8 7.1e-07 28.7 6.8 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC29981.1 - 1.1e-06 28.5 9.9 1.1e-06 28.5 6.9 2.8 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC29981.1 - 2e-06 27.4 10.2 2e-06 27.4 7.0 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC29981.1 - 1.3e-05 24.9 9.9 1.3e-05 24.9 6.9 2.6 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC29981.1 - 0.00017 21.2 9.4 0.00088 18.9 6.5 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_2 PF13639.1 EGC29981.1 - 0.00071 19.3 7.6 0.00071 19.3 5.2 2.5 2 0 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EGC29981.1 - 0.0017 18.0 2.5 0.0056 16.4 1.7 1.8 1 0 0 1 1 1 1 zf-RING of BARD1-type protein IBR PF01485.16 EGC29981.1 - 0.42 10.5 11.1 2 8.3 0.1 2.9 2 0 0 2 2 2 0 IBR domain Rpr2 PF04032.11 EGC29983.1 - 4.5e-19 68.0 0.6 5e-19 67.9 0.4 1.0 1 0 0 1 1 1 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain DAGAT PF03982.8 EGC29984.1 - 1.8e-110 368.2 0.0 2.2e-110 368.0 0.0 1.0 1 0 0 1 1 1 1 Diacylglycerol acyltransferase DUF2244 PF10003.4 EGC29984.1 - 0.053 12.8 0.8 0.21 10.9 1.0 1.5 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) Rer1 PF03248.8 EGC29984.1 - 0.16 11.5 3.0 0.29 10.7 2.1 1.4 1 0 0 1 1 1 0 Rer1 family Antimicrobial_8 PF08103.6 EGC29984.1 - 0.36 10.8 0.0 0.36 10.8 0.0 2.1 2 0 0 2 2 2 0 Uperin family NUDIX PF00293.23 EGC29985.1 - 6.8e-13 48.4 0.1 5.6e-07 29.2 0.0 2.2 2 0 0 2 2 2 2 NUDIX domain DUF2004 PF09406.5 EGC29985.1 - 0.027 14.5 0.6 0.074 13.1 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2004) CppA_C PF14507.1 EGC29985.1 - 0.069 13.3 0.5 0.2 11.8 0.1 1.9 2 0 0 2 2 2 0 CppA C-terminal VWC PF00093.13 EGC29986.1 - 0.031 14.3 24.4 0.11 12.6 6.6 2.4 2 0 0 2 2 2 0 von Willebrand factor type C domain Macoilin PF09726.4 EGC29986.1 - 0.87 7.7 15.5 0.85 7.8 10.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF4175 PF13779.1 EGC29988.1 - 9.5 3.7 5.6 17 2.9 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Methyltransf_11 PF08241.7 EGC29989.1 - 1.6e-16 60.5 0.0 2.9e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC29989.1 - 1.3e-10 41.2 0.0 1.7e-10 40.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC29989.1 - 1.6e-09 37.5 0.1 3e-09 36.6 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC29989.1 - 2.4e-09 37.5 0.0 1.1e-08 35.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC29989.1 - 1.5e-07 31.9 0.0 3.6e-07 30.7 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC29989.1 - 7.5e-05 23.0 0.0 0.00014 22.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC29989.1 - 0.00013 21.9 0.0 0.00026 21.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC29989.1 - 0.00021 20.4 0.0 0.00032 19.8 0.0 1.3 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EGC29989.1 - 0.00048 19.8 0.0 0.0055 16.3 0.0 2.2 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EGC29989.1 - 0.0047 16.3 0.0 0.0098 15.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EGC29989.1 - 0.011 15.0 0.0 0.018 14.3 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase RrnaAD PF00398.15 EGC29989.1 - 0.013 14.5 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase CbiA PF01656.18 EGC29989.1 - 0.022 14.1 0.0 0.054 12.9 0.0 1.6 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain FtsJ PF01728.14 EGC29989.1 - 0.073 13.0 0.0 0.15 12.0 0.0 1.8 1 1 0 1 1 1 0 FtsJ-like methyltransferase DUF2605 PF10792.4 EGC29989.1 - 0.22 11.1 0.8 0.38 10.4 0.1 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2605) Myotub-related PF06602.9 EGC29990.1 - 1.3e-113 379.4 2.7 1.6e-113 379.1 1.9 1.0 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain DSPc PF00782.15 EGC29990.1 - 0.0064 16.0 0.0 0.013 15.1 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Prokineticin PF06607.6 EGC29990.1 - 0.13 12.3 0.0 25 5.0 0.0 2.5 2 0 0 2 2 2 0 Prokineticin Y_phosphatase3 PF13350.1 EGC29990.1 - 0.14 12.4 0.0 0.24 11.6 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Peptidase_M1 PF01433.15 EGC29991.1 - 9.1e-74 248.8 0.0 1.7e-73 247.9 0.0 1.5 2 0 0 2 2 2 1 Peptidase family M1 Leuk-A4-hydro_C PF09127.6 EGC29991.1 - 2.6e-39 134.0 0.7 5.3e-39 133.0 0.5 1.5 1 0 0 1 1 1 1 Leukotriene A4 hydrolase, C-terminal Peptidase_MA_2 PF13485.1 EGC29991.1 - 4.5e-14 52.5 0.0 8e-14 51.7 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Terpene_synth_C PF03936.11 EGC29992.1 - 1.3e-05 24.5 1.4 4.5e-05 22.8 0.8 1.9 1 1 1 2 2 2 2 Terpene synthase family, metal binding domain Terpene_synth_C PF03936.11 EGC29993.1 - 6.6e-06 25.5 1.0 1.4e-05 24.5 0.7 1.6 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain PGK PF00162.14 EGC29993.1 - 0.16 10.4 0.0 0.23 9.9 0.0 1.2 1 0 0 1 1 1 0 Phosphoglycerate kinase p450 PF00067.17 EGC29994.1 - 1.6e-81 274.1 0.4 2e-81 273.9 0.3 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF2632 PF10943.3 EGC29994.1 - 1.1 8.7 3.8 0.43 10.0 1.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2632) Pkinase_Tyr PF07714.12 EGC29995.1 - 9e-12 44.5 0.1 2.1e-11 43.4 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase FAD-oxidase_C PF02913.14 EGC29997.1 - 9.4e-51 172.5 0.0 1.2e-50 172.1 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGC29997.1 - 6.3e-38 129.3 0.0 9.8e-38 128.7 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain CUE PF02845.11 EGC29998.1 - 8.6e-06 25.1 0.0 1.7e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 CUE domain RICTOR_N PF14664.1 EGC29998.1 - 0.4 9.2 0.5 1.2 7.6 0.3 1.8 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term RTBV_P46 PF06216.6 EGC29999.1 - 0.007 15.2 0.0 0.0097 14.7 0.0 1.2 1 0 0 1 1 1 1 Rice tungro bacilliform virus P46 protein Dimer_Tnp_hAT PF05699.9 EGC30000.1 - 2.8e-11 42.8 0.5 2.8e-11 42.8 0.3 1.8 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region CDC37_C PF08564.5 EGC30000.1 - 6.2e-05 22.7 0.7 0.0001 22.1 0.5 1.3 1 0 0 1 1 1 1 Cdc37 C terminal domain Exonuc_VII_L PF02601.10 EGC30000.1 - 0.095 11.8 3.2 0.11 11.7 2.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit RP-C_C PF11800.3 EGC30000.1 - 0.11 12.2 0.6 0.12 12.0 0.4 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region APG17 PF04108.7 EGC30001.1 - 1.2e-20 73.7 33.7 2e-16 59.7 3.4 2.3 2 1 0 2 2 2 2 Autophagy protein Apg17 DUF4413 PF14372.1 EGC30001.1 - 8.1 6.4 9.7 31 4.6 0.6 4.2 4 0 0 4 4 4 0 Domain of unknown function (DUF4413) DASH_Dam1 PF08653.5 EGC30001.1 - 8.8 6.1 10.8 0.8 9.5 0.6 3.7 3 1 1 4 4 4 0 DASH complex subunit Dam1 Pam16 PF03656.8 EGC30002.1 - 2.3e-12 46.8 0.3 2.7e-12 46.6 0.2 1.1 1 0 0 1 1 1 1 Pam16 Kelch_6 PF13964.1 EGC30003.1 - 3.8e-12 45.8 3.8 9.6e-07 28.7 0.1 4.4 3 1 1 4 4 4 2 Kelch motif Kelch_1 PF01344.20 EGC30003.1 - 1.3e-08 34.2 12.2 0.0019 17.6 0.1 5.8 6 0 0 6 6 6 3 Kelch motif Kelch_5 PF13854.1 EGC30003.1 - 2.5e-07 30.5 1.5 0.035 14.0 0.1 3.6 3 0 0 3 3 3 3 Kelch motif Kelch_4 PF13418.1 EGC30003.1 - 1.4e-06 27.9 1.2 0.057 13.1 0.0 3.9 4 0 0 4 4 3 2 Galactose oxidase, central domain zf-C3HC4 PF00097.20 EGC30003.1 - 4.4e-06 26.2 9.5 4.4e-06 26.2 6.6 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Kelch_2 PF07646.10 EGC30003.1 - 4.1e-05 23.1 2.6 0.75 9.6 0.0 4.1 4 0 0 4 4 4 2 Kelch motif Kelch_3 PF13415.1 EGC30003.1 - 4.4e-05 23.5 0.2 0.0094 16.1 0.0 3.9 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-RING_2 PF13639.1 EGC30003.1 - 0.00026 20.7 7.6 0.0015 18.2 5.3 2.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC30003.1 - 0.00032 20.6 10.2 0.00032 20.6 7.1 3.3 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC30003.1 - 0.00098 18.9 10.3 0.00098 18.9 7.1 3.3 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC30003.1 - 0.0019 17.9 3.5 0.0019 17.9 2.5 2.6 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EGC30003.1 - 0.0026 17.2 8.0 0.0069 15.8 5.6 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EGC30003.1 - 0.0056 16.3 7.9 0.0056 16.3 5.5 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-B_box PF00643.19 EGC30003.1 - 0.012 15.4 0.2 0.012 15.4 0.1 3.3 3 0 0 3 3 3 0 B-box zinc finger TCR PF03638.10 EGC30006.1 - 2.8e-24 84.6 63.5 4.7e-14 51.9 17.0 2.5 2 0 0 2 2 2 2 Tesmin/TSO1-like CXC domain, cysteine-rich domain Kelch_4 PF13418.1 EGC30007.1 - 2.7e-39 132.6 18.0 4.5e-09 35.9 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC30007.1 - 7.7e-37 124.6 13.2 1.1e-08 34.9 0.0 6.2 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC30007.1 - 2.5e-28 97.5 3.5 1e-07 31.7 0.0 6.0 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EGC30007.1 - 3.5e-28 96.8 14.6 6.7e-09 35.1 0.1 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC30007.1 - 5.6e-22 76.9 13.3 4.6e-06 26.5 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC30007.1 - 2.5e-16 58.6 5.2 5.9e-08 32.1 0.0 5.9 6 0 0 6 6 6 3 Kelch motif Rax2 PF12768.2 EGC30007.1 - 0.00092 18.5 8.0 0.097 11.8 0.2 3.4 1 1 0 3 3 3 2 Cortical protein marker for cell polarity CHAP PF05257.11 EGC30007.1 - 0.024 14.3 0.1 0.82 9.3 0.0 2.6 2 0 0 2 2 2 0 CHAP domain DUF814 PF05670.8 EGC30007.1 - 0.16 11.8 0.6 6.7 6.6 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF814) Syja_N PF02383.13 EGC30008.1 - 9.3e-89 297.3 0.5 9.3e-89 297.3 0.3 3.1 2 1 0 2 2 2 1 SacI homology domain WYL PF13280.1 EGC30008.1 - 0.023 14.5 0.1 0.054 13.3 0.0 1.6 1 0 0 1 1 1 0 WYL domain SNF5 PF04855.7 EGC30009.1 - 2.4e-40 138.5 6.6 9.1e-31 107.1 0.3 3.5 1 1 2 4 4 4 2 SNF5 / SMARCB1 / INI1 TFIIF_alpha PF05793.7 EGC30010.1 - 7.5e-21 74.0 76.8 3.4e-18 65.3 4.1 2.6 1 1 2 3 3 3 2 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Coiled PF05710.7 EGC30011.1 - 0.0064 16.9 3.6 0.0074 16.7 2.5 1.2 1 1 0 1 1 1 1 Coiled coil CBM_X2 PF03442.9 EGC30011.1 - 0.11 12.3 2.3 0.12 12.1 1.6 1.2 1 0 0 1 1 1 0 Carbohydrate binding domain X2 Cyt-b5 PF00173.23 EGC30012.1 - 9.2e-21 73.4 0.1 1.7e-20 72.6 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Bax1-I PF01027.15 EGC30012.1 - 0.078 12.5 6.5 0.12 11.9 4.5 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF4118 PF13493.1 EGC30012.1 - 0.59 10.3 7.4 1.5 9.0 5.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) DUF4419 PF14388.1 EGC30013.1 - 1e-15 57.7 3.2 5.9e-13 48.6 0.3 2.8 2 1 1 3 3 3 2 Domain of unknown function (DUF4419) Chordopox_G3 PF06129.7 EGC30013.1 - 0.42 10.7 5.8 1.8 8.7 1.9 2.6 2 0 0 2 2 2 0 Chordopoxvirus G3 protein Utp14 PF04615.8 EGC30014.1 - 3.4e-140 468.5 109.4 3.4e-140 468.5 75.8 2.1 1 1 1 2 2 2 1 Utp14 protein OTU PF02338.14 EGC30015.1 - 2.7e-19 69.9 2.0 4e-19 69.3 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGC30015.1 - 7e-09 35.3 10.3 4e-07 29.6 0.1 3.6 1 1 3 4 4 4 2 Peptidase C65 Otubain Sigma70_ner PF04546.8 EGC30015.1 - 3.5 7.1 24.4 0.67 9.5 13.6 2.1 1 1 0 1 1 1 0 Sigma-70, non-essential region Interfer-bind PF09294.5 EGC30016.1 - 0.0094 15.9 0.8 0.028 14.4 0.5 1.8 1 0 0 1 1 1 1 Interferon-alpha/beta receptor, fibronectin type III Barttin PF15462.1 EGC30017.1 - 1.6 8.3 6.4 0.46 10.0 1.4 2.2 2 0 0 2 2 2 0 Bartter syndrome, infantile, with sensorineural deafness (Barttin) ACOX PF01756.14 EGC30018.1 - 9.9e-23 80.4 0.0 1.8e-22 79.6 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGC30018.1 - 2.2e-11 43.0 0.1 4.6e-11 42.0 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGC30018.1 - 2e-05 24.7 0.0 3.5e-05 23.9 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Toxin_5 PF05294.8 EGC30018.1 - 0.043 14.0 1.1 0.1 12.8 0.8 1.7 1 0 0 1 1 1 0 Scorpion short toxin Tbf5 PF06331.7 EGC30019.1 - 2.1e-24 85.0 0.1 2.4e-24 84.8 0.1 1.0 1 0 0 1 1 1 1 Transcription factor TFIIH complex subunit Tfb5 DUF2075 PF09848.4 EGC30019.1 - 0.0012 17.9 0.2 0.0012 17.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) DEAD PF00270.24 EGC30019.1 - 0.0069 15.9 0.1 0.0076 15.7 0.1 1.1 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGC30019.1 - 0.019 15.1 0.1 0.021 14.9 0.1 1.1 1 0 0 1 1 1 0 AAA domain PGP_phosphatase PF09419.5 EGC30019.1 - 0.093 12.0 0.2 0.1 11.9 0.1 1.2 1 0 0 1 1 1 0 Mitochondrial PGP phosphatase AAA PF00004.24 EGC30019.1 - 0.11 12.6 0.1 0.13 12.5 0.1 1.0 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Pkinase PF00069.20 EGC30020.1 - 2.2e-10 40.1 0.0 3.9e-10 39.3 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30020.1 - 0.0025 16.9 0.0 0.004 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase HIGH_NTase1 PF05636.6 EGC30020.1 - 0.098 11.6 0.1 0.16 11.0 0.1 1.2 1 0 0 1 1 1 0 HIGH Nucleotidyl Transferase Gate PF07670.9 EGC30021.1 - 0.0046 16.8 0.1 0.0048 16.7 0.1 1.1 1 0 0 1 1 1 1 Nucleoside recognition DUF4176 PF13780.1 EGC30022.1 - 0.34 10.6 3.7 2.9 7.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4176) BAF1_ABF1 PF04684.8 EGC30022.1 - 1.4 7.7 29.3 2.3 6.9 20.3 1.5 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor SR-25 PF10500.4 EGC30022.1 - 1.4 8.3 14.8 1.4 8.3 2.4 2.4 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Peptidase_S49_N PF08496.5 EGC30022.1 - 1.7 8.4 6.0 3.1 7.5 4.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Serinc PF03348.10 EGC30022.1 - 7.4 5.1 9.8 10 4.7 6.8 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) DRIM PF07539.7 EGC30023.1 - 2.7e-35 120.8 9.7 4.1e-35 120.2 0.2 5.8 5 0 0 5 5 5 1 Down-regulated in metastasis HEAT PF02985.17 EGC30023.1 - 0.00012 21.8 0.0 33 4.9 0.0 6.5 5 0 0 5 5 5 1 HEAT repeat Ribosomal_L31e PF01198.14 EGC30024.1 - 1.4e-35 120.8 1.7 1.6e-35 120.5 1.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L31e Topoisom_I_N PF02919.10 EGC30025.1 - 5.7e-92 306.8 1.1 5.7e-92 306.8 0.7 2.7 3 1 0 3 3 3 1 Eukaryotic DNA topoisomerase I, DNA binding fragment Topoisom_I PF01028.15 EGC30025.1 - 6.1e-85 284.0 1.9 6.1e-85 284.0 1.3 2.1 2 0 0 2 2 2 1 Eukaryotic DNA topoisomerase I, catalytic core Topo_C_assoc PF14370.1 EGC30025.1 - 2.3e-30 104.0 1.3 2.3e-30 104.0 0.9 2.3 2 0 0 2 2 2 1 C-terminal topoisomerase domain EAP30 PF04157.11 EGC30026.1 - 1.8e-64 216.9 1.5 2e-64 216.8 1.0 1.0 1 0 0 1 1 1 1 EAP30/Vps36 family TFIIE_alpha PF02002.12 EGC30026.1 - 0.0031 17.0 0.1 0.009 15.4 0.1 1.9 1 0 0 1 1 1 1 TFIIE alpha subunit DUF2316 PF10078.4 EGC30026.1 - 0.04 13.8 3.6 0.68 9.9 0.1 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2316) Enkurin PF13864.1 EGC30026.1 - 0.053 13.7 0.7 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 Calmodulin-binding tRNA_lig_kinase PF08303.6 EGC30026.1 - 2.2 8.1 8.5 1.2 9.0 0.9 2.9 1 1 1 2 2 2 0 tRNA ligase kinase domain PNRC PF15365.1 EGC30027.1 - 1.3e-15 57.1 0.3 1.3e-15 57.1 0.2 3.0 2 1 0 2 2 2 1 Proline-rich nuclear receptor coactivator Herpes_LMP2 PF07415.6 EGC30027.1 - 0.15 10.6 3.0 0.1 11.1 1.1 1.4 1 1 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein IncA PF04156.9 EGC30027.1 - 0.76 9.3 7.2 1.1 8.8 5.0 1.2 1 0 0 1 1 1 0 IncA protein tRNA-synt_2b PF00587.20 EGC30028.1 - 2.4e-30 105.3 0.0 4.6e-30 104.4 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGC30028.1 - 2.2e-10 40.5 7.8 2.2e-10 40.5 5.4 1.7 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Pil1 PF13805.1 EGC30028.1 - 0.0019 17.4 0.5 0.0031 16.6 0.3 1.4 1 0 0 1 1 1 1 Eisosome component PIL1 UBA_3 PF09288.5 EGC30028.1 - 0.86 9.2 6.4 3.7 7.2 2.3 2.6 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain DUF4506 PF14958.1 EGC30030.1 - 1.4e-09 37.6 0.4 2.8e-09 36.6 0.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4506) Adaptin_binding PF10199.4 EGC30030.1 - 0.48 10.6 5.0 0.13 12.5 0.2 2.3 1 1 1 2 2 2 0 Alpha and gamma adaptin binding protein p34 Amidase_5 PF05382.8 EGC30030.1 - 3.6 7.2 7.0 0.56 9.8 0.4 2.2 2 0 0 2 2 2 0 Bacteriophage peptidoglycan hydrolase DUF1900 PF08954.6 EGC30031.1 - 1.3e-96 319.4 3.2 1.6e-51 173.3 0.1 3.7 4 0 0 4 4 4 2 Domain of unknown function (DUF1900) WD40 PF00400.27 EGC30031.1 - 5.1e-38 127.6 14.2 4.6e-08 32.6 0.1 8.9 10 0 0 10 10 10 6 WD domain, G-beta repeat DUF1899 PF08953.6 EGC30031.1 - 1.4e-30 104.6 3.0 5.7e-19 67.5 0.2 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF1899) DUF1652 PF07865.6 EGC30031.1 - 0.11 12.1 0.0 0.35 10.4 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1652) Cpn60_TCP1 PF00118.19 EGC30032.1 - 1e-30 106.8 25.8 2.5e-28 98.9 17.1 3.4 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family Elf-1_N PF12310.3 EGC30032.1 - 0.052 13.4 0.1 0.16 11.9 0.0 1.8 1 0 0 1 1 1 0 Transcription factor protein N terminal zf-CHCC PF10276.4 EGC30033.1 - 1.1e-16 60.3 0.7 1.5e-16 59.8 0.5 1.2 1 0 0 1 1 1 1 Zinc-finger domain COX5B PF01215.14 EGC30033.1 - 0.0032 17.1 0.1 0.0042 16.7 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb zf-AN1 PF01428.11 EGC30033.1 - 0.66 9.8 4.8 1 9.2 3.3 1.3 1 0 0 1 1 1 0 AN1-like Zinc finger SNF2_N PF00176.18 EGC30034.1 - 2.1e-63 213.9 3.4 5.7e-63 212.4 2.4 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC30034.1 - 1.2e-17 63.5 0.0 5.1e-17 61.5 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC30034.1 - 1.2e-07 31.3 0.0 4.1e-07 29.6 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase FAD-oxidase_C PF02913.14 EGC30035.1 - 3.6e-51 173.8 0.0 4.9e-51 173.4 0.0 1.2 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGC30035.1 - 1.8e-34 118.1 0.4 2.7e-34 117.6 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain DUF1183 PF06682.7 EGC30036.1 - 0.057 13.0 1.0 0.071 12.6 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) MscL PF01741.13 EGC30036.1 - 0.097 12.8 2.5 0.15 12.2 1.7 1.3 1 0 0 1 1 1 0 Large-conductance mechanosensitive channel, MscL Ctr PF04145.10 EGC30036.1 - 0.11 12.5 3.7 0.17 11.8 0.2 2.2 2 1 0 2 2 2 0 Ctr copper transporter family Tmemb_9 PF05434.6 EGC30036.1 - 0.35 10.6 5.3 0.053 13.2 0.4 1.9 1 1 2 3 3 3 0 TMEM9 DUF2929 PF11151.3 EGC30036.1 - 1.7 8.7 9.8 1.4e+02 2.6 6.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2929) PTH2 PF01981.11 EGC30037.1 - 3.7e-43 145.9 0.4 4.2e-43 145.7 0.3 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase PTH2 DUF3749 PF12568.3 EGC30037.1 - 0.067 12.7 0.0 0.085 12.4 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribosomal_L7Ae PF01248.21 EGC30038.1 - 1.9e-22 78.5 1.3 1.9e-22 78.5 0.9 1.8 3 0 0 3 3 3 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family DUF1092 PF06485.6 EGC30039.1 - 0.023 13.6 0.3 0.028 13.3 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1092) Bap31 PF05529.7 EGC30039.1 - 0.025 14.0 0.6 0.025 14.0 0.4 1.9 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like DUF3972 PF13118.1 EGC30039.1 - 0.065 13.3 1.5 0.065 13.3 1.0 2.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3972) DUF970 PF06153.6 EGC30039.1 - 0.085 12.8 2.6 0.37 10.7 0.2 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF970) 4HBT PF03061.17 EGC30040.1 - 0.04 14.0 0.0 0.068 13.3 0.0 1.4 1 0 0 1 1 1 0 Thioesterase superfamily 4HBT PF03061.17 EGC30041.1 - 7.2e-06 26.0 0.0 9.7e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily Apc9 PF12856.2 EGC30041.1 - 1.5 8.9 6.1 16 5.6 4.2 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 9 PEX11 PF05648.9 EGC30042.1 - 1.3e-19 70.3 9.0 1.4e-08 34.2 1.8 3.2 2 1 0 3 3 3 3 Peroxisomal biogenesis factor 11 (PEX11) CNH PF00780.17 EGC30043.1 - 4.3e-33 114.9 2.0 4.3e-33 114.9 1.4 2.0 2 0 0 2 2 2 1 CNH domain Vps39_2 PF10367.4 EGC30043.1 - 2.4e-29 101.7 0.1 2.4e-29 101.7 0.1 2.8 2 0 0 2 2 2 1 Vacuolar sorting protein 39 domain 2 Clathrin PF00637.15 EGC30043.1 - 7.7e-08 32.0 30.6 8.2e-06 25.4 4.4 5.0 5 1 1 6 6 6 3 Region in Clathrin and VPS Vps39_1 PF10366.4 EGC30043.1 - 0.0019 18.1 0.1 0.0019 18.1 0.0 5.0 4 1 1 5 5 5 1 Vacuolar sorting protein 39 domain 1 DUF2685 PF10886.3 EGC30043.1 - 0.0066 16.4 0.1 0.0066 16.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2685) DUF202 PF02656.10 EGC30044.1 - 0.02 15.0 0.2 0.037 14.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF202) Asp PF00026.18 EGC30045.1 - 9.5e-44 149.9 0.1 1.4e-43 149.3 0.1 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGC30045.1 - 9.2e-15 54.5 0.0 4.4e-14 52.3 0.0 1.9 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGC30045.1 - 3.6e-12 46.5 0.2 5e-12 46.0 0.1 1.2 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGC30045.1 - 0.015 15.7 0.0 2.3 8.7 0.0 3.1 3 0 0 3 3 3 0 Aspartyl protease WD40 PF00400.27 EGC30046.1 - 5.8e-17 60.8 11.9 6.6e-08 32.1 0.2 6.1 6 0 0 6 6 6 4 WD domain, G-beta repeat Acetyltransf_1 PF00583.19 EGC30047.1 - 2e-09 37.3 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGC30047.1 - 3.5e-07 30.4 0.0 4e-07 30.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC30047.1 - 4.2e-07 29.6 0.0 1.9e-06 27.5 0.0 2.0 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 EGC30047.1 - 4e-05 23.6 0.4 5.9e-05 23.0 0.3 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC30047.1 - 0.00081 19.5 0.0 0.0011 19.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC30047.1 - 0.015 15.4 0.0 0.026 14.7 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC30048.1 - 8.2e-15 54.6 0.0 1.3e-14 54.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGC30048.1 - 1.2e-07 31.7 1.1 1.8e-07 31.2 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC30048.1 - 2.1e-07 31.2 0.0 2.5e-07 30.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC30048.1 - 6.4e-07 29.0 0.1 1.4e-06 28.0 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGC30048.1 - 4.8e-06 26.6 0.0 6.6e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC30048.1 - 2.5e-05 24.3 0.1 4.9e-05 23.4 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC30048.1 - 0.041 13.7 0.0 0.079 12.8 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGC30048.1 - 0.053 13.3 0.0 0.28 11.0 0.0 2.0 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC30048.1 - 0.068 13.0 0.0 0.09 12.6 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC30049.1 - 1.2e-12 47.7 0.0 1.9e-12 47.0 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC30049.1 - 1.9e-09 37.6 0.0 2.4e-09 37.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC30049.1 - 4.3e-08 32.8 0.0 7.3e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGC30049.1 - 3.5e-06 27.2 0.0 4.4e-06 26.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC30049.1 - 3.8e-06 26.9 0.0 6.4e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC30049.1 - 4.1e-05 23.5 0.1 5.1e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC30049.1 - 0.0001 22.1 0.0 0.00022 21.0 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_13 PF13880.1 EGC30049.1 - 0.11 12.2 0.0 0.27 11.0 0.0 1.6 1 1 0 1 1 1 0 ESCO1/2 acetyl-transferase MMR_HSR1 PF01926.18 EGC30050.1 - 7e-07 29.2 1.9 7e-06 25.9 1.3 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGC30050.1 - 1.4e-06 27.5 8.2 0.00054 19.1 0.6 3.8 3 0 0 3 3 3 2 AIG1 family DUF258 PF03193.11 EGC30050.1 - 0.00017 20.8 0.1 0.00017 20.8 0.1 2.3 3 0 0 3 3 3 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC30050.1 - 0.00028 20.3 1.0 0.00076 18.9 0.1 2.2 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA PF00004.24 EGC30050.1 - 0.0046 17.1 0.5 0.058 13.5 0.1 3.0 1 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) FtsK_SpoIIIE PF01580.13 EGC30050.1 - 0.0047 16.4 0.2 0.023 14.1 0.0 2.1 3 0 0 3 3 3 1 FtsK/SpoIIIE family T2SE PF00437.15 EGC30050.1 - 0.0048 15.8 0.2 0.0048 15.8 0.1 2.4 2 1 1 3 3 3 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EGC30050.1 - 0.0049 16.0 0.0 0.011 14.9 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 EGC30050.1 - 0.0087 15.5 0.0 0.023 14.1 0.0 1.7 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGC30050.1 - 0.012 15.7 0.3 0.37 10.9 0.0 2.9 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGC30050.1 - 0.02 14.6 0.0 0.061 13.0 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGC30050.1 - 0.095 12.6 0.0 0.29 11.1 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain Cyclin_N PF00134.18 EGC30051.1 - 3.1e-11 42.9 0.2 5.7e-11 42.0 0.1 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGC30051.1 - 3.9e-10 40.3 0.0 5.3e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Cyclin HATPase_c PF02518.21 EGC30052.1 - 5.3e-26 90.5 0.0 1.1e-25 89.5 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC30052.1 - 1.2e-24 86.4 0.0 2.7e-24 85.3 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGC30052.1 - 2.9e-19 68.7 0.1 2.9e-19 68.7 0.1 2.2 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain DUF4118 PF13493.1 EGC30052.1 - 0.031 14.4 4.0 0.089 12.9 2.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4118) ELMO_CED12 PF04727.8 EGC30053.1 - 4.8e-41 140.1 1.7 8.3e-41 139.3 1.2 1.4 1 0 0 1 1 1 1 ELMO/CED-12 family UPF0118 PF01594.11 EGC30053.1 - 6.5 5.6 5.8 0.97 8.3 0.4 2.1 3 0 0 3 3 3 0 Domain of unknown function DUF20 Opiods_neuropep PF01160.13 EGC30054.1 - 0.0034 17.1 15.5 3.4 7.4 0.2 5.7 5 0 0 5 5 5 4 Vertebrate endogenous opioids neuropeptide Rap_GAP PF02145.10 EGC30055.1 - 3.4e-62 209.1 4.1 3.4e-62 209.1 2.8 2.1 2 0 0 2 2 2 1 Rap/ran-GAP RPEL PF02755.10 EGC30055.1 - 0.01 15.1 0.3 0.027 13.7 0.2 1.8 1 0 0 1 1 1 0 RPEL repeat MFS_1 PF07690.11 EGC30056.1 - 5.3e-31 107.6 33.0 9.8e-26 90.2 14.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC30056.1 - 3e-16 59.0 5.7 3e-16 59.0 4.0 2.6 2 2 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGC30056.1 - 0.0018 16.7 5.8 0.0018 16.7 4.0 3.2 1 1 1 2 2 2 1 MFS/sugar transport protein DUF2003 PF09404.5 EGC30057.1 - 1.8e-34 118.9 4.4 4.7e-33 114.2 2.6 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF2003) RPM2 PF08579.6 EGC30057.1 - 0.0014 18.7 0.7 0.0014 18.7 0.5 2.4 3 0 0 3 3 3 1 Mitochondrial ribonuclease P subunit (RPM2) Actin PF00022.14 EGC30058.1 - 1.7e-157 523.8 0.0 2e-157 523.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC30058.1 - 0.14 12.5 0.0 0.41 11.0 0.0 1.7 1 1 1 2 2 2 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Amino_oxidase PF01593.19 EGC30059.1 - 2e-48 165.5 0.0 4.3e-48 164.5 0.0 1.5 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC30059.1 - 6.1e-13 48.5 0.1 1.9e-12 46.9 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGC30059.1 - 0.00015 20.9 0.1 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_binding_2 PF00890.19 EGC30059.1 - 0.00051 19.0 0.1 0.0007 18.5 0.1 1.1 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGC30059.1 - 0.0015 17.5 0.1 0.0023 16.9 0.1 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGC30059.1 - 0.0026 17.8 0.0 0.0047 17.0 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC30059.1 - 0.0064 16.8 0.1 0.016 15.5 0.0 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGC30059.1 - 0.0075 15.3 0.1 0.012 14.6 0.1 1.2 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGC30059.1 - 0.0075 14.7 0.0 0.013 13.9 0.0 1.3 1 0 0 1 1 1 1 HI0933-like protein FAD_oxidored PF12831.2 EGC30059.1 - 0.019 14.0 0.1 0.037 13.0 0.0 1.5 2 0 0 2 2 2 0 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGC30059.1 - 0.02 13.8 0.0 0.03 13.2 0.0 1.3 1 0 0 1 1 1 0 Lycopene cyclase protein GDI PF00996.13 EGC30059.1 - 0.058 11.7 0.0 0.083 11.1 0.0 1.2 1 0 0 1 1 1 0 GDP dissociation inhibitor Pyr_redox_2 PF07992.9 EGC30059.1 - 0.13 12.0 0.0 0.44 10.4 0.0 1.8 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGC30059.1 - 0.14 11.0 0.1 0.28 9.9 0.0 1.5 2 0 0 2 2 2 0 Glucose inhibited division protein A N6_N4_Mtase PF01555.13 EGC30060.1 - 1e-05 25.1 0.9 0.00052 19.5 0.0 2.2 2 0 0 2 2 2 2 DNA methylase Methyltransf_26 PF13659.1 EGC30060.1 - 0.001 19.1 0.0 0.0018 18.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain POLO_box PF00659.13 EGC30060.1 - 0.3 11.0 2.7 11 6.0 0.0 2.7 3 0 0 3 3 3 0 POLO box duplicated region Amidohydro_4 PF13147.1 EGC30061.1 - 1.7e-30 107.0 0.0 2e-30 106.8 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGC30061.1 - 1.4e-13 51.1 0.5 1.9e-11 44.2 0.3 2.3 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGC30061.1 - 2.1e-12 46.6 0.3 4.8e-12 45.5 0.2 1.6 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGC30061.1 - 1.4e-11 44.2 0.3 3.9e-07 29.6 0.0 2.7 2 1 0 2 2 2 2 Amidohydrolase family Kdo PF06293.9 EGC30062.1 - 0.0056 15.7 0.4 0.016 14.2 0.1 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Phage_int_SAM_2 PF12834.2 EGC30062.1 - 0.011 16.1 0.3 0.031 14.6 0.0 1.8 2 0 0 2 2 2 0 Phage integrase, N-terminal Oxidored_FMN PF00724.15 EGC30065.1 - 9.6e-71 238.5 0.0 1.1e-70 238.3 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGC30065.1 - 0.016 14.0 0.0 0.033 13.0 0.0 1.4 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) SR-25 PF10500.4 EGC30066.1 - 0.31 10.4 6.3 0.51 9.7 4.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.8 EGC30066.1 - 1.9 7.1 8.0 2.7 6.6 5.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) Menin PF05053.8 EGC30066.1 - 7.3 4.6 12.2 12 3.8 8.5 1.4 1 0 0 1 1 1 0 Menin ABC_tran PF00005.22 EGC30067.1 - 7.5e-52 175.2 0.0 2.2e-26 92.8 0.1 2.9 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGC30067.1 - 3.2e-51 174.3 56.5 2.6e-26 92.4 14.7 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGC30067.1 - 1.9e-17 64.2 20.5 3.9e-08 33.6 0.0 7.1 5 2 0 6 6 6 3 AAA domain SMC_N PF02463.14 EGC30067.1 - 2.3e-07 30.2 0.0 0.72 9.0 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC30067.1 - 1.4e-05 24.5 1.4 0.041 13.4 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 EGC30067.1 - 0.00049 19.5 0.4 0.44 9.9 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain DUF258 PF03193.11 EGC30067.1 - 0.019 14.1 1.1 0.41 9.8 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC30067.1 - 0.02 14.2 0.1 0.44 9.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC30067.1 - 0.032 14.0 0.2 3 7.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGC30067.1 - 0.085 13.1 0.1 0.085 13.1 0.0 5.0 5 1 0 5 5 5 0 AAA domain SbcCD_C PF13558.1 EGC30067.1 - 0.17 11.7 0.0 6.6 6.7 0.0 3.0 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGC30067.1 - 0.23 10.5 0.0 7.5 5.5 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin DUF1469 PF07332.6 EGC30067.1 - 0.72 9.5 8.8 5 6.8 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1469) ABC2_membrane PF01061.19 EGC30067.1 - 3.1 6.9 41.8 0.013 14.6 12.7 4.1 4 0 0 4 4 4 0 ABC-2 type transporter Spore_YhcN_YlaJ PF09580.5 EGC30068.1 - 0.00043 20.4 18.6 0.016 15.2 4.1 2.2 2 0 0 2 2 2 2 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) Gti1_Pac2 PF09729.4 EGC30068.1 - 0.0049 16.7 8.1 0.3 10.9 1.9 2.3 2 0 0 2 2 2 2 Gti1/Pac2 family Ctr PF04145.10 EGC30068.1 - 0.079 12.9 2.5 2.7 8.0 0.7 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Apc15p PF05841.6 EGC30068.1 - 0.28 11.8 26.5 0.59 10.8 7.0 2.4 2 0 0 2 2 2 0 Apc15p protein Secretin_N_2 PF07655.8 EGC30068.1 - 0.68 10.3 54.1 0.43 11.0 13.2 2.4 2 0 0 2 2 2 0 Secretin N-terminal domain CENP-B_dimeris PF09026.5 EGC30068.1 - 0.76 10.0 7.7 7.3 6.8 0.2 3.1 3 0 0 3 3 3 0 Centromere protein B dimerisation domain SprA-related PF12118.3 EGC30068.1 - 1.3 8.2 12.3 2.3 7.4 3.3 2.1 2 0 0 2 2 2 0 SprA-related family POX PF07526.6 EGC30068.1 - 6 7.0 13.2 9.2 6.4 1.0 2.4 2 0 0 2 2 2 0 Associated with HOX Pox_Ag35 PF03286.9 EGC30068.1 - 8.8 5.8 19.3 0.35 10.3 2.6 2.4 2 0 0 2 2 2 0 Pox virus Ag35 surface protein ABC2_membrane PF01061.19 EGC30069.1 - 4.9e-90 300.2 47.9 9.9e-49 165.3 17.9 2.3 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC30069.1 - 9.9e-52 174.8 2.7 8.6e-27 94.1 0.0 2.8 3 0 0 3 3 2 2 ABC transporter AAA_29 PF13555.1 EGC30069.1 - 9.6e-09 34.6 0.1 0.00099 18.5 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC30069.1 - 1.4e-08 34.3 0.0 0.0068 15.8 0.0 3.3 3 0 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGC30069.1 - 5e-08 32.3 2.4 0.0007 18.8 0.0 2.6 3 0 0 3 3 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC30069.1 - 1e-07 32.1 0.0 0.015 15.4 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC30069.1 - 2.8e-07 30.6 0.0 0.0097 15.9 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGC30069.1 - 1.1e-06 29.5 0.2 0.16 12.7 0.0 3.4 3 0 0 3 3 2 2 AAA domain PDR_assoc PF08370.6 EGC30069.1 - 1.4e-06 27.7 0.3 1.4e-06 27.7 0.2 2.9 3 0 0 3 3 2 1 Plant PDR ABC transporter associated Rad17 PF03215.10 EGC30069.1 - 4.4e-06 25.6 0.0 0.029 13.0 0.0 2.5 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein ABC2_membrane_3 PF12698.2 EGC30069.1 - 4.5e-06 25.9 22.1 4.5e-06 25.9 15.3 3.7 3 2 0 3 3 2 2 ABC-2 family transporter protein AAA_33 PF13671.1 EGC30069.1 - 1.1e-05 25.2 0.0 0.079 12.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGC30069.1 - 5.3e-05 23.0 0.0 0.049 13.3 0.0 2.7 2 0 0 2 2 2 1 Archaeal ATPase AAA_28 PF13521.1 EGC30069.1 - 7.2e-05 22.7 0.4 0.43 10.5 0.1 2.4 2 0 0 2 2 2 2 AAA domain NACHT PF05729.7 EGC30069.1 - 0.00019 21.1 0.4 0.13 11.8 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_21 PF13304.1 EGC30069.1 - 0.00019 21.4 26.2 0.13 12.2 0.0 6.6 5 2 0 6 6 6 1 AAA domain AAA PF00004.24 EGC30069.1 - 0.0002 21.5 0.1 0.2 11.8 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGC30069.1 - 0.00026 21.1 0.0 0.51 10.5 0.0 2.9 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 EGC30069.1 - 0.00073 19.4 0.0 1.3 8.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_18 PF13238.1 EGC30069.1 - 0.001 19.3 0.0 0.037 14.3 0.0 4.9 5 0 0 5 5 4 2 AAA domain PDR_CDR PF06422.7 EGC30069.1 - 0.0013 18.3 0.1 0.0013 18.3 0.1 3.4 3 0 0 3 3 3 1 CDR ABC transporter IstB_IS21 PF01695.12 EGC30069.1 - 0.0014 18.0 0.0 0.25 10.7 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_10 PF12846.2 EGC30069.1 - 0.0018 17.7 0.2 0.8 9.0 0.0 2.4 2 0 0 2 2 2 1 AAA-like domain ArgK PF03308.11 EGC30069.1 - 0.0043 15.8 0.1 0.9 8.2 0.0 2.2 2 0 0 2 2 2 1 ArgK protein FtsK_SpoIIIE PF01580.13 EGC30069.1 - 0.0073 15.8 0.1 0.18 11.2 0.0 2.2 2 0 0 2 2 2 1 FtsK/SpoIIIE family NTPase_1 PF03266.10 EGC30069.1 - 0.0078 15.9 1.0 0.89 9.2 0.0 3.1 3 0 0 3 3 3 1 NTPase AAA_5 PF07728.9 EGC30069.1 - 0.013 15.1 1.2 1.9 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Miro PF08477.8 EGC30069.1 - 0.018 15.5 0.0 6.1 7.3 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA_19 PF13245.1 EGC30069.1 - 0.021 14.5 0.0 9 6.1 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain SbcCD_C PF13558.1 EGC30069.1 - 0.024 14.5 0.0 2.4 8.1 0.0 3.1 3 0 0 3 3 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGC30069.1 - 0.029 13.4 0.0 6.2 5.8 0.0 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_30 PF13604.1 EGC30069.1 - 0.033 13.7 0.0 3.4 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGC30069.1 - 0.042 13.3 0.0 1.5 8.2 0.0 2.3 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain MobB PF03205.9 EGC30069.1 - 0.052 13.2 0.1 10 5.7 0.0 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Viral_helicase1 PF01443.13 EGC30069.1 - 0.053 13.0 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase UPF0079 PF02367.12 EGC30069.1 - 0.095 12.3 0.5 1.9 8.1 0.1 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 cobW PF02492.14 EGC30069.1 - 0.096 12.1 1.5 1.2 8.5 0.0 2.6 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain Mg_chelatase PF01078.16 EGC30069.1 - 0.12 11.4 0.1 5.4 6.1 0.0 2.6 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI PduV-EutP PF10662.4 EGC30069.1 - 0.16 11.4 1.7 8.3 5.8 0.1 2.5 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGC30069.1 - 0.79 9.6 10.4 0.96 9.3 0.0 3.4 4 0 0 4 4 2 0 AAA domain TCR PF03638.10 EGC30070.1 - 0.15 11.9 25.7 0.29 11.0 17.8 1.4 1 0 0 1 1 1 0 Tesmin/TSO1-like CXC domain, cysteine-rich domain VESA1_N PF12785.2 EGC30070.1 - 0.99 8.2 9.6 1.5 7.7 6.7 1.2 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 UCH PF00443.24 EGC30071.1 - 3.6e-45 154.1 1.0 6e-45 153.4 0.7 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGC30071.1 - 2.5e-14 53.1 6.2 4.8e-14 52.2 4.3 1.4 1 0 0 1 1 1 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGC30071.1 - 4.1e-07 29.7 0.7 8.1e-07 28.7 0.5 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase WD40 PF00400.27 EGC30072.1 - 2.2e-15 55.8 28.9 0.0015 18.3 0.4 6.6 6 0 0 6 6 6 5 WD domain, G-beta repeat IncA PF04156.9 EGC30072.1 - 0.0068 16.0 18.2 0.0068 16.0 12.6 3.7 1 1 2 3 3 3 2 IncA protein Prok-RING_1 PF14446.1 EGC30072.1 - 0.026 14.2 6.5 0.06 13.0 4.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 C1_1 PF00130.17 EGC30072.1 - 0.23 11.2 9.0 0.65 9.7 6.3 1.7 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CLU PF13236.1 EGC30073.1 - 3.9e-49 167.0 0.3 2.6e-48 164.3 0.0 2.5 3 0 0 3 3 3 1 Clustered mitochondria SH2 PF00017.19 EGC30073.1 - 3e-09 36.5 0.0 1.1e-08 34.7 0.0 2.0 1 0 0 1 1 1 1 SH2 domain eIF3_p135 PF12807.2 EGC30073.1 - 5e-09 36.3 0.3 5e-09 36.3 0.2 3.0 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 TPR_11 PF13414.1 EGC30073.1 - 0.0068 16.0 0.2 0.8 9.3 0.1 2.6 2 0 0 2 2 2 1 TPR repeat dNK PF01712.14 EGC30074.1 - 5.2e-25 88.0 0.1 8.6e-25 87.3 0.1 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase Thymidylate_kin PF02223.12 EGC30074.1 - 1.2e-07 31.3 0.4 2.6e-07 30.2 0.0 1.8 2 1 0 2 2 2 1 Thymidylate kinase AAA_17 PF13207.1 EGC30074.1 - 0.0002 22.1 0.0 0.00048 20.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC30074.1 - 0.00029 20.7 0.0 0.00061 19.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC30074.1 - 0.00043 20.2 0.0 0.00059 19.8 0.0 1.2 1 0 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EGC30074.1 - 0.0023 17.5 0.0 0.0041 16.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGC30074.1 - 0.0033 17.7 1.1 0.0073 16.6 0.1 2.0 2 1 0 2 2 2 1 AAA domain PPK2 PF03976.9 EGC30074.1 - 0.051 12.8 0.0 0.21 10.8 0.0 1.9 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) RGS PF00615.14 EGC30075.1 - 6.6e-15 55.2 0.1 1.5e-14 54.1 0.1 1.6 1 1 0 1 1 1 1 Regulator of G protein signaling domain Secretin_N_2 PF07655.8 EGC30075.1 - 1.1 9.6 9.7 0.35 11.2 4.4 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain ArfGap PF01412.13 EGC30076.1 - 0.084 12.6 0.1 0.084 12.6 0.1 6.7 4 1 0 5 5 5 0 Putative GTPase activating protein for Arf dCMP_cyt_deam_1 PF00383.17 EGC30077.1 - 1e-17 63.6 0.7 1.6e-17 62.9 0.5 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC30077.1 - 0.018 14.8 0.5 3.4 7.5 0.0 2.2 1 1 1 2 2 2 0 Bd3614-like deaminase DUF1632 PF07857.7 EGC30078.1 - 6.3e-55 186.1 10.0 6.3e-55 186.1 6.9 2.0 1 1 1 2 2 2 1 CEO family (DUF1632) Sugar_transport PF06800.7 EGC30078.1 - 2e-05 23.8 21.4 2.7e-05 23.3 4.0 2.9 2 2 1 3 3 3 2 Sugar transport protein DUF606 PF04657.8 EGC30078.1 - 0.00021 21.4 11.6 0.00021 21.4 8.1 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF606 DUF792 PF05632.6 EGC30078.1 - 0.033 13.5 0.0 0.056 12.7 0.0 1.3 1 0 0 1 1 1 0 Borrelia burgdorferi protein of unknown function (DUF792) RRM_1 PF00076.17 EGC30079.1 - 7.7e-19 67.0 0.1 8.7e-19 66.9 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC30079.1 - 7.6e-13 48.2 0.0 8.2e-13 48.1 0.0 1.0 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC30079.1 - 0.0028 17.4 0.0 0.0036 17.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CSTF2_hinge PF14327.1 EGC30080.1 - 1.7e-15 56.8 21.4 1.7e-15 56.8 14.8 3.0 2 1 0 2 2 2 1 Hinge domain of cleavage stimulation factor subunit 2 Vfa1 PF08432.5 EGC30081.1 - 0.006 16.6 11.7 0.0092 16.0 8.1 1.2 1 0 0 1 1 1 1 AAA-ATPase Vps4-associated protein 1 DUF4175 PF13779.1 EGC30081.1 - 0.63 7.6 12.4 0.8 7.3 8.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DDE_3 PF13358.1 EGC30083.1 - 0.0029 17.3 0.0 0.0031 17.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WCCH PF03716.9 EGC30083.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif Lyase_1 PF00206.15 EGC30085.1 - 9.4e-117 389.6 0.0 1.3e-116 389.1 0.0 1.2 1 0 0 1 1 1 1 Lyase FumaraseC_C PF10415.4 EGC30085.1 - 2.3e-26 91.6 0.1 1.4e-25 89.1 0.0 2.3 2 0 0 2 2 2 1 Fumarase C C-terminus SBP_bac_3 PF00497.15 EGC30085.1 - 0.0015 17.8 0.1 0.0039 16.4 0.0 1.6 2 0 0 2 2 2 1 Bacterial extracellular solute-binding proteins, family 3 Pept_tRNA_hydro PF01195.14 EGC30086.1 - 4.2e-50 169.8 0.3 4.9e-50 169.5 0.2 1.0 1 0 0 1 1 1 1 Peptidyl-tRNA hydrolase SRP54_N PF02881.14 EGC30086.1 - 0.024 14.7 0.8 0.51 10.4 0.3 2.3 2 0 0 2 2 2 0 SRP54-type protein, helical bundle domain WD40 PF00400.27 EGC30088.1 - 1.5e-79 259.2 18.7 1e-13 50.5 0.1 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat eIF2A PF08662.6 EGC30088.1 - 2.5e-15 56.6 1.4 1.4e-06 28.1 0.0 4.0 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGC30088.1 - 7.1e-11 40.9 1.5 0.034 12.2 0.0 4.6 2 1 3 5 5 5 4 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGC30088.1 - 2.6e-06 26.4 8.2 0.034 12.9 0.1 4.6 1 1 3 4 4 4 3 Nup133 N terminal like Cytochrom_D1 PF02239.11 EGC30088.1 - 4.4e-05 21.9 0.1 0.00082 17.7 0.0 2.5 1 1 1 2 2 2 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EGC30088.1 - 0.00069 19.1 0.2 0.0025 17.3 0.1 1.9 1 1 0 1 1 1 1 PQQ-like domain Nbas_N PF15492.1 EGC30088.1 - 0.015 14.3 1.4 8.4 5.3 0.0 3.8 1 1 3 4 4 4 0 Neuroblastoma-amplified sequence, N terminal PQQ_3 PF13570.1 EGC30088.1 - 0.021 15.1 0.3 4.6 7.6 0.1 3.1 2 1 0 2 2 2 0 PQQ-like domain PD40 PF07676.7 EGC30088.1 - 0.15 11.8 1.9 4.1 7.1 0.1 3.5 3 0 0 3 3 3 0 WD40-like Beta Propeller Repeat SecE PF00584.15 EGC30089.1 - 3e-14 52.3 0.1 3.4e-14 52.1 0.0 1.0 1 0 0 1 1 1 1 SecE/Sec61-gamma subunits of protein translocation complex UBA PF00627.26 EGC30090.1 - 9.7e-11 41.1 0.0 2.9e-10 39.6 0.0 1.8 2 0 0 2 2 2 1 UBA/TS-N domain UBA_3 PF09288.5 EGC30090.1 - 0.00063 19.2 0.0 0.0012 18.4 0.0 1.4 1 0 0 1 1 1 1 Fungal ubiquitin-associated domain UBA_4 PF14555.1 EGC30090.1 - 0.00064 19.2 0.2 0.0017 17.8 0.0 1.8 2 0 0 2 2 2 1 UBA-like domain DUF1421 PF07223.6 EGC30090.1 - 0.09 12.5 11.7 0.59 9.8 8.0 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1421) LSM PF01423.17 EGC30091.1 - 1.5e-12 46.8 0.1 2.2e-12 46.3 0.1 1.3 1 0 0 1 1 1 1 LSM domain HMG_CoA_synt_C PF08540.5 EGC30092.1 - 2.3e-94 316.0 6.9 3e-94 315.6 4.8 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase C terminal HMG_CoA_synt_N PF01154.12 EGC30092.1 - 1.1e-89 298.5 0.1 1.6e-89 298.0 0.1 1.2 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A synthase N terminal IF3_C PF00707.17 EGC30093.1 - 7.5e-09 35.2 0.1 3.5e-08 33.0 0.1 2.2 1 0 0 1 1 1 1 Translation initiation factor IF-3, C-terminal domain Rft-1 PF04506.8 EGC30094.1 - 1.3e-54 185.5 43.0 3.4e-54 184.1 29.8 1.7 1 1 0 1 1 1 1 Rft protein Gemini_mov PF01708.11 EGC30094.1 - 0.021 14.3 0.3 1.6 8.3 0.8 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF912 PF06024.7 EGC30094.1 - 0.067 13.2 23.8 0.052 13.6 1.0 3.7 4 0 0 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Eapp_C PF10238.4 EGC30094.1 - 4.3 7.2 16.3 0.19 11.5 0.1 2.2 2 0 0 2 2 2 0 E2F-associated phosphoprotein Sas10_Utp3 PF04000.10 EGC30095.1 - 1.5e-15 57.1 0.3 1.5e-15 57.1 0.2 1.7 1 1 1 2 2 2 1 Sas10/Utp3/C1D family Fungal_trans_2 PF11951.3 EGC30095.1 - 0.0021 16.7 0.2 0.0024 16.5 0.1 1.0 1 0 0 1 1 1 1 Fungal specific transcription factor domain PilJ PF13675.1 EGC30095.1 - 0.11 12.7 0.4 2.2 8.6 0.3 2.0 1 1 0 1 1 1 0 Type IV pili methyl-accepting chemotaxis transducer N-term DUF4640 PF15480.1 EGC30095.1 - 0.16 11.4 2.7 0.6 9.6 0.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4640) XhlA PF10779.4 EGC30095.1 - 2 8.3 4.9 20 5.1 0.0 2.3 2 0 0 2 2 2 0 Haemolysin XhlA DUF663 PF04950.7 EGC30096.1 - 4.7e-83 278.5 0.4 4.7e-83 278.5 0.3 3.1 4 0 0 4 4 3 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGC30096.1 - 2e-29 100.9 0.4 9.9e-29 98.7 0.0 2.5 2 0 0 2 2 2 1 AARP2CN (NUC121) domain GTP_EFTU PF00009.22 EGC30096.1 - 3.3e-09 36.4 0.0 1.2e-06 28.0 0.0 3.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC30096.1 - 9.1e-05 21.9 0.0 0.00036 20.0 0.0 1.9 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGC30096.1 - 0.00019 21.3 0.7 0.00069 19.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA PF00004.24 EGC30096.1 - 0.00027 21.1 0.0 0.0007 19.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EGC30096.1 - 0.00055 20.4 0.0 0.0031 17.9 0.0 2.4 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EGC30096.1 - 0.0011 19.1 0.0 0.0027 17.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGC30096.1 - 0.0011 18.6 0.1 0.0068 16.1 0.1 2.4 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MMR_HSR1 PF01926.18 EGC30096.1 - 0.0014 18.5 0.2 0.0077 16.1 0.1 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGC30096.1 - 0.0017 18.4 0.0 0.004 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGC30096.1 - 0.0037 18.0 0.0 0.0037 18.0 0.0 4.1 5 1 0 5 5 2 1 AAA domain FeoB_N PF02421.13 EGC30096.1 - 0.0045 16.2 0.2 0.21 10.8 0.0 2.6 3 0 0 3 3 3 1 Ferrous iron transport protein B AAA_33 PF13671.1 EGC30096.1 - 0.016 15.1 0.0 0.048 13.5 0.0 1.9 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGC30096.1 - 0.028 14.6 0.0 0.083 13.0 0.0 1.9 1 0 0 1 1 1 0 RNA helicase Actin PF00022.14 EGC30097.1 - 8.2e-26 90.3 8.9 2.8e-12 45.7 0.0 4.7 3 1 2 5 5 5 4 Actin UQ_con PF00179.21 EGC30098.1 - 3.3e-44 149.7 0.1 3.8e-44 149.5 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC30098.1 - 0.0004 20.1 0.0 0.00068 19.4 0.0 1.4 1 1 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC30098.1 - 0.16 11.8 0.9 0.92 9.4 0.1 2.1 1 1 1 2 2 2 0 RWD domain GTP_cyclohydroI PF01227.17 EGC30099.1 - 1.3e-74 249.3 0.7 1.6e-74 249.0 0.5 1.1 1 0 0 1 1 1 1 GTP cyclohydrolase I QueF PF14489.1 EGC30099.1 - 0.0011 18.8 0.0 0.0027 17.5 0.0 1.6 1 0 0 1 1 1 1 QueF-like protein MIF PF01187.13 EGC30099.1 - 0.042 13.9 0.1 0.074 13.1 0.0 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) DNase_II PF03265.10 EGC30100.1 - 4.8e-35 121.1 18.5 4.3e-29 101.5 9.2 2.7 2 1 0 2 2 2 2 Deoxyribonuclease II DUF3439 PF11921.3 EGC30102.1 - 0.0077 15.9 5.0 0.017 14.8 3.5 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC30102.1 - 0.11 12.2 9.7 0.2 11.4 6.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Pox_ATPase-GT PF10640.4 EGC30103.1 - 0.014 14.1 0.2 0.015 14.0 0.1 1.1 1 0 0 1 1 1 0 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase FlaC_arch PF05377.6 EGC30105.1 - 0.02 14.7 3.8 0.02 14.7 2.6 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) 3H PF02829.9 EGC30105.1 - 0.057 13.4 2.7 0.21 11.6 1.8 2.0 1 0 0 1 1 1 0 3H domain DUF2404 PF10296.4 EGC30107.1 - 5.5e-25 87.3 0.8 1e-24 86.4 0.1 1.9 2 0 0 2 2 2 1 Putative integral membrane protein conserved region (DUF2404) PH PF00169.24 EGC30107.1 - 2.8e-06 27.4 0.2 8.3e-06 25.9 0.1 1.8 1 0 0 1 1 1 1 PH domain Arm PF00514.18 EGC30108.1 - 4e-85 277.0 15.9 5.3e-12 45.0 0.0 9.2 9 0 0 9 9 9 8 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC30108.1 - 1.3e-23 83.0 0.0 3.7e-08 33.5 0.0 5.9 1 1 6 7 7 7 6 HEAT repeats HEAT_EZ PF13513.1 EGC30108.1 - 1.7e-19 69.6 3.0 2.3e-07 31.0 0.0 6.0 5 1 1 6 6 5 4 HEAT-like repeat IBB PF01749.15 EGC30108.1 - 1.6e-18 66.6 8.7 2.9e-18 65.8 6.1 1.4 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGC30108.1 - 1.3e-11 43.5 9.5 0.0023 17.8 0.0 8.2 9 1 0 9 9 9 2 HEAT repeat Adaptin_N PF01602.15 EGC30108.1 - 3.6e-08 32.2 0.3 3.5e-05 22.3 0.0 3.1 1 1 2 3 3 3 3 Adaptin N terminal region Arm_2 PF04826.8 EGC30108.1 - 1.6e-06 27.4 0.1 0.0032 16.6 0.1 2.8 1 1 2 3 3 3 3 Armadillo-like HEAT_PBS PF03130.11 EGC30108.1 - 4e-05 23.6 0.3 0.073 13.5 0.0 5.0 6 0 0 6 6 6 1 PBS lyase HEAT-like repeat V-ATPase_H_C PF11698.3 EGC30108.1 - 0.0001 22.1 0.0 1.6 8.6 0.0 4.1 3 1 1 4 4 4 3 V-ATPase subunit H RICTOR_V PF14668.1 EGC30108.1 - 0.00086 19.1 1.2 4.2 7.3 0.0 4.6 4 1 1 5 5 5 1 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EGC30108.1 - 0.024 12.9 1.6 0.6 8.3 0.1 2.4 2 1 0 2 2 2 0 Proteasome non-ATPase 26S subunit XPC-binding PF09280.6 EGC30108.1 - 1.9 8.0 6.3 0.84 9.1 0.1 3.1 3 0 0 3 3 3 0 XPC-binding domain Ank_4 PF13637.1 EGC30109.1 - 0.0099 16.3 0.0 0.027 14.9 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ribonuclease_3 PF00636.21 EGC30110.1 - 0.11 12.9 17.2 3.4 8.1 11.9 3.1 1 1 0 1 1 1 0 Ribonuclease III domain Exonuc_VII_L PF02601.10 EGC30110.1 - 0.75 8.9 11.3 1.1 8.3 7.8 1.2 1 0 0 1 1 1 0 Exonuclease VII, large subunit Sulf_transp PF04143.9 EGC30111.1 - 2.3e-06 27.5 17.1 0.00023 21.1 1.8 4.6 4 2 2 6 6 6 2 Sulphur transport SH2_2 PF14633.1 EGC30112.1 - 9.8e-46 155.5 0.1 1.8e-45 154.7 0.0 1.4 1 0 0 1 1 1 1 SH2 domain HHH_7 PF14635.1 EGC30112.1 - 9.2e-22 77.1 0.4 2e-21 76.0 0.3 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif YqgF PF14639.1 EGC30112.1 - 1.6e-19 69.9 0.0 3.5e-19 68.8 0.0 1.6 1 0 0 1 1 1 1 Holliday-junction resolvase-like of SPT6 DLD PF14878.1 EGC30112.1 - 7e-19 68.0 0.1 7e-19 68.0 0.1 2.4 2 0 0 2 2 2 1 Death-like domain of SPT6 HTH_44 PF14641.1 EGC30112.1 - 4.8e-16 58.8 1.8 2e-15 56.8 1.3 2.1 1 0 0 1 1 1 1 Helix-turn-helix DNA-binding domain of SPT6 DUF3942 PF13078.1 EGC30112.1 - 0.021 14.9 0.4 1.4 9.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3942) HHH_3 PF12836.2 EGC30112.1 - 0.038 13.9 0.0 0.097 12.6 0.0 1.7 1 0 0 1 1 1 0 Helix-hairpin-helix motif Pyr_redox_2 PF07992.9 EGC30113.1 - 1.3e-36 126.3 0.7 2.3e-36 125.5 0.5 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGC30113.1 - 2.9e-33 114.1 1.2 5.7e-33 113.2 0.5 1.8 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGC30113.1 - 8.3e-18 64.5 0.2 2.3e-17 63.1 0.1 1.8 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC30113.1 - 3.8e-12 46.7 0.0 8.9e-10 38.9 0.0 2.4 1 1 1 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC30113.1 - 0.004 16.1 0.0 0.015 14.2 0.0 1.8 1 1 1 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGC30113.1 - 0.016 14.1 2.2 1.2 7.9 0.0 3.0 3 1 0 3 3 3 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EGC30113.1 - 0.016 13.6 0.8 2 6.7 0.0 2.9 3 0 0 3 3 3 0 HI0933-like protein Shikimate_DH PF01488.15 EGC30113.1 - 0.042 13.9 0.3 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase CPSase_L_chain PF00289.17 EGC30113.1 - 0.075 13.1 0.0 0.35 10.9 0.0 2.1 2 0 0 2 2 2 0 Carbamoyl-phosphate synthase L chain, N-terminal domain zf-Tim10_DDP PF02953.10 EGC30114.1 - 2.6e-10 39.4 5.3 2.6e-10 39.4 3.6 1.5 1 1 1 2 2 2 1 Tim10/DDP family zinc finger DUF4354 PF14263.1 EGC30114.1 - 0.11 12.2 0.6 0.11 12.1 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4354) DUF842 PF05811.8 EGC30114.1 - 0.13 11.7 4.3 0.43 10.0 3.0 1.8 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) Pkinase PF00069.20 EGC30115.1 - 4e-75 252.3 0.0 4.5e-75 252.1 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30115.1 - 6.2e-33 113.9 0.0 9e-33 113.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC30115.1 - 0.00043 20.0 0.1 0.0053 16.5 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC30115.1 - 0.0027 16.5 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kinase-like PF14531.1 EGC30115.1 - 0.0037 16.2 0.0 0.018 14.0 0.0 2.0 2 0 0 2 2 2 1 Kinase-like SR-25 PF10500.4 EGC30117.1 - 0.029 13.8 0.3 0.032 13.6 0.2 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein NBP1 PF08537.5 EGC30117.1 - 0.076 12.2 1.2 0.077 12.1 0.9 1.1 1 0 0 1 1 1 0 Fungal Nap binding protein NBP1 UMPH-1 PF05822.7 EGC30118.1 - 0.12 11.6 0.2 0.13 11.5 0.1 1.1 1 0 0 1 1 1 0 Pyrimidine 5'-nucleotidase (UMPH-1) DUF1451 PF07295.6 EGC30118.1 - 0.16 11.6 1.2 0.21 11.3 0.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) Ion_trans PF00520.26 EGC30120.1 - 0.0053 16.0 0.1 0.0053 16.0 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein DUF4405 PF14358.1 EGC30120.1 - 0.2 11.8 1.4 0.31 11.2 1.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) DUF3430 PF11912.3 EGC30120.1 - 0.82 9.4 11.1 1.2 8.8 7.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) DUF3317 PF11779.3 EGC30120.1 - 3.1 7.2 6.0 6 6.3 4.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3317) AAA_23 PF13476.1 EGC30120.1 - 8.5 6.6 14.4 10 6.4 10.0 1.1 1 0 0 1 1 1 0 AAA domain I_LWEQ PF01608.12 EGC30122.1 - 0.00011 22.1 9.6 0.013 15.4 1.1 3.6 2 1 1 3 3 3 3 I/LWEQ domain TerB PF05099.8 EGC30122.1 - 0.065 12.9 2.1 0.081 12.6 0.5 1.8 2 0 0 2 2 2 0 Tellurite resistance protein TerB Rdx PF10262.4 EGC30123.1 - 8.6e-05 22.4 0.3 0.45 10.5 0.0 2.7 2 0 0 2 2 2 2 Rdx family Cadherin-like PF12733.2 EGC30123.1 - 0.0029 17.8 3.1 1.5 9.1 0.2 3.4 3 0 0 3 3 3 2 Cadherin-like beta sandwich domain YwpF PF14183.1 EGC30123.1 - 0.022 14.4 0.5 7.3 6.3 0.0 2.4 2 0 0 2 2 2 0 YwpF-like protein Med20 PF08612.6 EGC30123.1 - 0.024 13.7 0.2 0.49 9.4 0.0 2.3 2 0 0 2 2 2 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex Big_2 PF02368.13 EGC30123.1 - 0.13 12.1 14.6 2.3 8.1 0.1 4.5 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 2) Brr6_like_C_C PF10104.4 EGC30124.1 - 6.1e-09 35.5 1.0 6.1e-09 35.5 0.7 5.4 4 2 2 6 6 6 2 Di-sulfide bridge nucleocytoplasmic transport domain Virul_fac_BrkB PF03631.10 EGC30124.1 - 0.00016 21.1 13.2 0.0015 17.9 5.1 2.9 2 1 0 2 2 2 2 Virulence factor BrkB DUF1129 PF06570.6 EGC30124.1 - 0.0032 16.8 0.4 0.0032 16.8 0.2 3.6 2 2 2 4 4 4 1 Protein of unknown function (DUF1129) 7tm_1 PF00001.16 EGC30124.1 - 0.53 9.3 18.8 0.077 12.1 1.3 3.5 1 1 2 3 3 3 0 7 transmembrane receptor (rhodopsin family) DUF2615 PF11027.3 EGC30124.1 - 0.96 9.4 4.7 1.5 8.7 0.3 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF2615) DUF3357 PF11837.3 EGC30124.1 - 1.7 8.5 15.9 4.9 7.0 0.1 4.2 2 2 3 5 5 5 0 Domain of unknown function (DUF3357) Shisa PF13908.1 EGC30124.1 - 2.4 8.3 0.0 2.4 8.3 0.0 4.7 2 2 2 5 5 5 0 Wnt and FGF inhibitory regulator DUF4131 PF13567.1 EGC30124.1 - 5.1 6.4 13.4 48 3.3 0.9 3.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4131) zf-C3HC4_3 PF13920.1 EGC30125.1 - 1.5e-07 30.9 4.3 2.3e-07 30.3 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC30125.1 - 5.3e-06 25.9 11.4 5.2e-05 22.8 7.8 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30125.1 - 6.5e-06 25.7 8.6 1.3e-05 24.8 6.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC30125.1 - 1e-05 25.4 11.1 6.8e-05 22.8 7.7 2.1 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC30125.1 - 0.00031 20.5 9.2 0.0013 18.5 6.4 1.9 1 1 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC30125.1 - 0.00058 19.9 3.1 0.00099 19.1 2.1 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGC30125.1 - 0.002 17.8 2.8 0.0044 16.7 1.9 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EGC30125.1 - 0.015 14.8 4.5 0.033 13.7 3.1 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EGC30125.1 - 0.02 14.7 6.5 0.02 14.7 4.5 2.6 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING SurA_N_2 PF13623.1 EGC30125.1 - 0.04 13.9 0.0 4.7 7.1 0.0 2.1 2 0 0 2 2 2 0 SurA N-terminal domain zf-Apc11 PF12861.2 EGC30125.1 - 0.12 12.1 1.6 0.23 11.3 1.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Oxidored_q1_N PF00662.15 EGC30125.1 - 0.14 11.7 2.2 0.24 10.9 1.5 1.3 1 0 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus zf-RING_4 PF14570.1 EGC30125.1 - 0.17 11.4 7.5 0.33 10.5 5.2 1.5 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Coleoptericin PF06286.6 EGC30125.1 - 0.22 11.3 2.3 0.72 9.7 1.6 1.8 1 1 0 1 1 1 0 Coleoptericin DUF2393 PF09624.5 EGC30125.1 - 1.5 8.3 6.8 0.53 9.8 2.3 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) WD40 PF00400.27 EGC30127.1 - 3.8e-59 194.5 9.3 1.3e-12 47.1 0.5 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nucleoporin_N PF08801.6 EGC30127.1 - 3.9e-06 25.8 1.5 0.043 12.5 0.0 4.0 1 1 2 4 4 4 2 Nup133 N terminal like PQQ_2 PF13360.1 EGC30127.1 - 0.0047 16.4 2.9 0.68 9.3 1.9 3.2 1 1 0 1 1 1 1 PQQ-like domain Kelch_6 PF13964.1 EGC30127.1 - 0.084 13.0 0.2 24 5.3 0.0 4.2 5 0 0 5 5 5 0 Kelch motif Rsm22 PF09243.5 EGC30128.1 - 1.1e-72 244.3 0.0 2.6e-72 243.1 0.0 1.6 2 0 0 2 2 2 1 Mitochondrial small ribosomal subunit Rsm22 Methyltransf_23 PF13489.1 EGC30128.1 - 2.9e-06 27.1 0.0 1.6e-05 24.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC30128.1 - 6.2e-05 23.4 0.0 0.032 14.7 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC30128.1 - 0.00082 18.5 0.0 0.0023 17.0 0.0 1.8 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGC30128.1 - 0.0042 17.6 0.0 0.04 14.5 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC30128.1 - 0.056 13.4 0.0 0.13 12.2 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase domain ATP-synt_A PF00119.15 EGC30129.1 - 0.098 12.1 0.1 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 ATP synthase A chain Macoilin PF09726.4 EGC30130.1 - 0.4 8.9 14.4 0.44 8.7 10.0 1.0 1 0 0 1 1 1 0 Transmembrane protein SF3b1 PF08920.5 EGC30130.1 - 3.6 7.5 8.0 2.5 8.1 2.8 2.4 2 1 0 2 2 2 0 Splicing factor 3B subunit 1 Neur_chan_memb PF02932.11 EGC30130.1 - 5.6 6.7 6.6 8.3 6.2 4.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Topo_Zn_Ribbon PF08272.6 EGC30133.1 - 0.053 12.8 0.0 0.081 12.2 0.0 1.3 1 0 0 1 1 1 0 Topoisomerase I zinc-ribbon-like UCH PF00443.24 EGC30134.1 - 1.2e-09 37.6 37.2 1.2e-09 37.6 25.8 5.0 3 2 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase LRR_6 PF13516.1 EGC30135.1 - 5.1e-30 100.1 73.1 0.01 15.8 0.2 17.1 17 0 0 17 17 17 12 Leucine Rich repeat LRR_4 PF12799.2 EGC30135.1 - 4.9e-05 22.8 68.0 0.09 12.4 1.5 9.8 3 3 9 12 12 12 8 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC30135.1 - 0.0022 17.7 51.1 6.6 7.1 0.1 13.3 13 2 1 14 14 14 4 Leucine Rich Repeat LRR_8 PF13855.1 EGC30135.1 - 0.0038 16.9 53.2 0.029 14.1 2.4 8.8 4 3 4 9 9 9 3 Leucine rich repeat F-box-like PF12937.2 EGC30135.1 - 0.035 13.8 0.1 0.089 12.5 0.1 1.7 1 0 0 1 1 1 0 F-box-like YusW PF14039.1 EGC30135.1 - 0.54 10.5 5.7 12 6.2 0.1 4.1 2 1 0 3 3 3 0 YusW-like protein Phage-tail_2 PF09096.5 EGC30135.1 - 0.58 9.7 4.6 1.3 8.5 0.1 3.2 3 1 0 3 3 3 0 Baseplate structural protein, domain 2 LRR_7 PF13504.1 EGC30135.1 - 1.6 9.2 36.7 33 5.2 0.2 11.1 14 0 0 14 14 14 0 Leucine rich repeat FNIP PF05725.7 EGC30136.1 - 2.5e-107 350.6 32.8 9.3e-18 63.9 0.9 8.1 4 1 3 9 9 9 9 FNIP Repeat Cys_rich_VLP PF14194.1 EGC30136.1 - 0.012 15.2 0.3 6.1 6.6 0.1 3.9 3 2 0 3 3 3 0 Cysteine-rich VLP LRR_5 PF13306.1 EGC30136.1 - 0.15 11.7 2.0 4.9 6.8 0.1 3.4 1 1 0 2 2 2 0 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC30136.1 - 1.1 9.2 27.8 9.8 6.2 0.2 8.9 4 3 7 11 11 11 0 Protein of unknown function (DUF1769) DDE_Tnp_4 PF13359.1 EGC30137.1 - 1e-09 38.1 0.1 1.3e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC30137.1 - 0.016 14.7 0.1 0.02 14.4 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain Vinculin PF01044.14 EGC30138.1 - 4.6e-06 24.9 0.2 4.6e-06 24.9 0.1 1.0 1 0 0 1 1 1 1 Vinculin family P53_C PF11619.3 EGC30138.1 - 0.12 12.1 0.1 0.15 11.8 0.1 1.3 1 0 0 1 1 1 0 Transcription factor P53 - C terminal domain DUF3430 PF11912.3 EGC30139.1 - 9.3e-18 64.8 31.9 1.1e-17 64.6 21.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Cys_Met_Meta_PP PF01053.15 EGC30140.1 - 1.4e-26 92.6 0.1 1.8e-26 92.3 0.0 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGC30140.1 - 2.6e-06 26.6 0.1 3.9e-06 26.0 0.1 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2738 PF10927.3 EGC30140.1 - 0.0076 15.3 1.2 0.015 14.3 0.2 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF2738) zf-C3HC4_2 PF13923.1 EGC30142.1 - 9.9e-06 25.4 10.0 9.9e-06 25.4 6.9 3.4 2 2 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC30142.1 - 0.00015 21.3 12.2 0.00015 21.3 8.4 3.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC30142.1 - 0.009 15.6 1.0 0.009 15.6 0.7 2.7 1 1 2 3 3 3 1 Seven in absentia protein family zf-RING_2 PF13639.1 EGC30142.1 - 0.021 14.6 9.9 0.021 14.6 6.9 3.4 2 1 0 2 2 2 0 Ring finger domain zf-U11-48K PF05253.7 EGC30142.1 - 0.027 14.1 0.2 12 5.7 0.0 2.9 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger zf-TRAF PF02176.13 EGC30142.1 - 0.033 14.5 29.9 1.5 9.2 0.1 4.8 1 1 3 4 4 4 0 TRAF-type zinc finger DUF4026 PF13218.1 EGC30142.1 - 0.093 11.5 0.3 0.13 11.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4026) NB-ARC PF00931.17 EGC30142.1 - 0.36 9.6 3.6 0.14 10.9 0.1 1.8 2 0 0 2 2 2 0 NB-ARC domain zf-C2H2_jaz PF12171.3 EGC30142.1 - 2.6 8.3 10.1 1.8 8.8 0.7 4.0 3 0 0 3 3 3 0 Zinc-finger double-stranded RNA-binding zf-TRAF PF02176.13 EGC30143.1 - 3.3e-10 40.1 40.2 6.8e-09 35.9 6.6 5.3 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC30143.1 - 8.2e-05 22.5 11.1 8.2e-05 22.5 7.7 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC30143.1 - 0.00063 19.3 12.2 0.00063 19.3 8.4 3.1 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-U11-48K PF05253.7 EGC30143.1 - 0.0095 15.6 0.9 15 5.3 0.0 4.1 3 0 0 3 3 3 1 U11-48K-like CHHC zinc finger Rsm1 PF08600.5 EGC30143.1 - 0.01 15.6 2.3 0.018 14.8 0.2 2.5 1 1 0 1 1 1 0 Rsm1-like Sina PF03145.11 EGC30143.1 - 0.017 14.8 2.1 0.017 14.8 1.4 3.6 2 1 1 4 4 4 0 Seven in absentia protein family IncA PF04156.9 EGC30143.1 - 0.54 9.8 3.4 0.99 8.9 2.4 1.4 1 0 0 1 1 1 0 IncA protein Mito_carr PF00153.22 EGC30145.1 - 8.5e-51 169.6 8.4 3.9e-23 80.9 0.2 3.0 2 1 1 3 3 3 3 Mitochondrial carrier protein LMBR1 PF04791.11 EGC30145.1 - 0.0065 15.1 0.0 0.014 13.9 0.0 1.5 2 0 0 2 2 2 1 LMBR1-like membrane protein DUF2372 PF10178.4 EGC30147.1 - 0.011 15.8 0.0 4.9 7.3 0.0 2.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2372) DUF498 PF04430.9 EGC30147.1 - 0.038 13.5 3.5 3.7 7.1 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) zf-C2H2_7 PF15269.1 EGC30147.1 - 1.3 8.9 4.9 43 4.0 0.1 3.6 4 0 0 4 4 4 0 Zinc-finger DUF2968 PF11180.3 EGC30148.1 - 0.63 9.4 9.6 0.21 10.9 3.5 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2968) Codanin-1_C PF15296.1 EGC30149.1 - 0.071 12.9 1.1 0.13 12.1 0.6 1.6 1 1 0 1 1 1 0 Codanin-1 C-terminus Claudin_2 PF13903.1 EGC30150.1 - 0.00088 18.9 1.1 0.00088 18.9 0.8 2.2 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3021 PF11457.3 EGC30150.1 - 0.0085 15.9 0.4 0.052 13.4 0.0 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3021) NADH5_C PF06455.6 EGC30150.1 - 0.037 13.4 4.1 0.14 11.4 0.6 2.1 2 0 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus Zip PF02535.17 EGC30150.1 - 0.085 11.8 2.7 0.052 12.5 0.5 1.7 2 0 0 2 2 2 0 ZIP Zinc transporter DUF2142 PF09913.4 EGC30150.1 - 4.9 5.7 7.2 0.62 8.6 2.0 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2142) PARP PF00644.15 EGC30151.1 - 7.6e-55 185.5 0.1 2.2e-54 184.0 0.0 1.9 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC30151.1 - 2e-39 134.2 3.8 3.4e-39 133.5 2.6 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGC30151.1 - 2e-18 66.1 0.4 8.8e-18 64.0 0.2 2.3 1 1 1 2 2 2 1 WGR domain zf-PARP PF00645.13 EGC30151.1 - 7.4e-18 64.5 0.1 1.8e-17 63.3 0.1 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region PADR1 PF08063.7 EGC30151.1 - 2.8e-17 61.8 1.3 2.8e-17 61.8 0.9 1.8 2 0 0 2 2 2 1 PADR1 (NUC008) domain Arg_tRNA_synt_N PF03485.11 EGC30151.1 - 0.072 13.6 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Arginyl tRNA synthetase N terminal domain DUF3571 PF12095.3 EGC30152.1 - 0.37 11.0 3.6 1.4 9.1 2.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3571) BUD22 PF09073.5 EGC30153.1 - 0.076 12.0 34.4 0.1 11.6 23.8 1.2 1 0 0 1 1 1 0 BUD22 SEEEED PF14797.1 EGC30153.1 - 5 7.2 38.3 0.072 13.2 21.2 1.9 2 0 0 2 2 2 0 Serine-rich region of AP3B1, clathrin-adaptor complex RCC1 PF00415.13 EGC30154.1 - 7e-58 192.6 13.3 1.4e-12 47.6 0.0 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC30154.1 - 6.5e-32 108.4 19.1 8.4e-06 25.2 0.0 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat TIR_2 PF13676.1 EGC30154.1 - 0.019 15.1 0.0 0.67 10.1 0.0 3.1 2 2 0 2 2 2 0 TIR domain Ank_3 PF13606.1 EGC30154.1 - 0.03 14.5 0.0 0.15 12.3 0.0 2.2 2 0 0 2 2 2 0 Ankyrin repeat LETM1 PF07766.8 EGC30155.1 - 2.8e-13 49.5 1.4 5.6e-13 48.5 1.0 1.5 1 0 0 1 1 1 1 LETM1-like protein Cyt-b5 PF00173.23 EGC30156.1 - 1.1e-26 92.4 0.4 1.2e-26 92.2 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PI3_PI4_kinase PF00454.22 EGC30157.1 - 3e-40 138.1 0.2 1.7e-39 135.6 0.1 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGC30157.1 - 3.4e-23 81.7 0.3 1.1e-22 80.1 0.2 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) CGI-121 PF08617.5 EGC30158.1 - 8.6e-24 84.0 4.8 9.9e-24 83.8 3.3 1.0 1 0 0 1 1 1 1 Kinase binding protein CGI-121 MotCF PF09158.5 EGC30158.1 - 0.033 13.8 2.3 0.064 12.9 0.3 2.1 2 0 0 2 2 2 0 Bacteriophage T4 MotA, C-terminal B3_4 PF03483.12 EGC30158.1 - 0.048 13.1 0.2 0.065 12.7 0.1 1.4 1 1 0 1 1 1 0 B3/4 domain Pox_E8 PF03394.8 EGC30158.1 - 0.094 12.0 0.3 0.16 11.2 0.2 1.3 1 1 0 1 1 1 0 Poxvirus E8 protein RasGEF PF00617.14 EGC30159.1 - 5.5e-62 208.8 0.8 1.2e-61 207.7 0.5 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC30159.1 - 3.2e-26 91.4 1.1 3.2e-26 91.4 0.8 2.7 4 0 0 4 4 4 1 RasGEF N-terminal motif UDG PF03167.14 EGC30160.1 - 8.5e-24 83.7 0.0 1.4e-23 83.0 0.0 1.3 1 0 0 1 1 1 1 Uracil DNA glycosylase superfamily MIP-T3 PF10243.4 EGC30160.1 - 0.084 11.3 31.4 0.11 10.9 21.8 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 EGC30160.1 - 0.28 9.4 0.7 0.3 9.3 0.5 1.3 1 0 0 1 1 1 0 Membrane transport protein DUF2413 PF10310.4 EGC30160.1 - 5.8 5.6 22.3 8 5.1 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) ACC_central PF08326.7 EGC30161.1 - 9.2e-190 632.2 7.3 1.4e-189 631.7 5.1 1.2 1 0 0 1 1 1 1 Acetyl-CoA carboxylase, central region Carboxyl_trans PF01039.17 EGC30161.1 - 2.6e-155 517.5 0.0 3.6e-155 517.0 0.0 1.2 1 0 0 1 1 1 1 Carboxyl transferase domain CPSase_L_D2 PF02786.12 EGC30161.1 - 1.8e-52 177.7 0.0 4.3e-52 176.4 0.0 1.6 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGC30161.1 - 5.4e-26 90.8 0.1 1.4e-25 89.5 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGC30161.1 - 6.9e-20 71.0 0.0 1.5e-19 69.9 0.0 1.6 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain ATP-grasp_4 PF13535.1 EGC30161.1 - 1.4e-14 54.2 0.0 4.6e-14 52.5 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain Biotin_lipoyl PF00364.17 EGC30161.1 - 5.8e-09 35.4 0.0 1.3e-08 34.2 0.0 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme ATP-grasp PF02222.17 EGC30161.1 - 1.6e-07 30.8 0.3 5.5e-07 29.1 0.0 1.9 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGC30161.1 - 3.8e-05 23.6 0.0 9.5e-05 22.3 0.0 1.7 1 0 0 1 1 1 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGC30161.1 - 0.0002 20.7 0.0 0.00054 19.3 0.0 1.7 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus GTP_EFTU PF00009.22 EGC30162.1 - 3e-58 196.3 0.0 4.2e-58 195.8 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGC30162.1 - 1.8e-34 117.8 0.0 3.9e-34 116.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGC30162.1 - 3.8e-19 68.3 0.0 1.1e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC30162.1 - 8.9e-15 54.5 0.2 3e-14 52.8 0.1 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGC30162.1 - 2e-14 53.1 0.0 4.8e-14 51.9 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II Corona_nucleoca PF00937.13 EGC30163.1 - 6.2 5.6 14.3 10 4.9 9.9 1.3 1 0 0 1 1 1 0 Coronavirus nucleocapsid protein COBRA1 PF06209.8 EGC30164.1 - 0.026 13.1 0.8 0.027 13.0 0.6 1.0 1 0 0 1 1 1 0 Cofactor of BRCA1 (COBRA1) Myb_DNA-binding PF00249.26 EGC30164.1 - 0.037 14.0 0.1 0.15 12.1 0.1 1.9 1 1 0 1 1 1 0 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC30164.1 - 0.04 14.0 0.5 0.082 13.0 0.4 1.6 1 1 0 1 1 1 0 Myb-like DNA-binding domain ERGIC_N PF13850.1 EGC30164.1 - 0.068 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) zf-C3Hc3H PF13891.1 EGC30165.1 - 7.8e-34 115.5 16.9 4.3e-17 61.9 3.2 2.5 2 0 0 2 2 2 2 Potential DNA-binding domain zf-primase PF09329.6 EGC30165.1 - 6.7e-05 22.4 2.9 0.0085 15.6 0.4 3.1 2 0 0 2 2 2 2 Primase zinc finger GAGA_bind PF06217.7 EGC30166.1 - 0.042 13.8 4.8 0.047 13.6 3.3 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Peptidase_S49_N PF08496.5 EGC30166.1 - 0.099 12.4 7.1 0.13 12.0 4.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal KAT11 PF08214.6 EGC30166.1 - 0.48 9.4 6.4 0.6 9.1 4.4 1.1 1 0 0 1 1 1 0 Histone acetylation protein Peptidase_C1 PF00112.18 EGC30167.1 - 7.6e-62 209.0 6.1 7.6e-62 209.0 4.2 1.5 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC30167.1 - 5.2e-16 58.6 8.9 8.6e-16 57.9 6.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC30167.1 - 2.3e-05 23.1 0.0 0.0047 15.5 0.0 2.3 2 0 0 2 2 2 2 Peptidase C1-like family FeoC PF09012.5 EGC30167.1 - 0.11 12.2 0.0 0.43 10.3 0.0 2.0 1 0 0 1 1 1 0 FeoC like transcriptional regulator HSP20 PF00011.16 EGC30168.1 - 8.2e-17 60.9 0.5 1.3e-16 60.2 0.4 1.3 1 0 0 1 1 1 1 Hsp20/alpha crystallin family MA3 PF02847.12 EGC30168.1 - 0.02 14.5 0.2 0.034 13.8 0.1 1.3 1 0 0 1 1 1 0 MA3 domain PrgH PF09480.5 EGC30168.1 - 0.088 11.6 1.8 0.11 11.3 0.5 1.6 2 0 0 2 2 2 0 Type III secretion system protein PrgH-EprH (PrgH) CS PF04969.11 EGC30168.1 - 0.29 11.6 2.9 0.3 11.6 0.7 2.1 2 1 0 2 2 2 0 CS domain MF_alpha_N PF05436.6 EGC30170.1 - 0.03 13.9 0.0 0.062 12.9 0.0 1.5 1 0 0 1 1 1 0 Mating factor alpha precursor N-terminus ETRAMP PF09716.5 EGC30170.1 - 0.092 12.7 0.0 0.52 10.2 0.0 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Cortexin PF11057.3 EGC30170.1 - 0.25 10.9 1.0 0.47 10.0 0.0 1.9 2 0 0 2 2 2 0 Cortexin of kidney DnaJ PF00226.26 EGC30171.1 - 1.8e-25 88.4 0.5 1.3e-24 85.6 0.4 2.7 1 0 0 1 1 1 1 DnaJ domain zf-C2H2_jaz PF12171.3 EGC30171.1 - 5.2e-10 39.1 10.4 2.1e-09 37.2 3.4 3.0 2 0 0 2 2 2 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC30171.1 - 5.9e-07 29.4 2.6 5.9e-07 29.4 1.8 2.6 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2 PF00096.21 EGC30171.1 - 0.00016 21.8 8.5 0.0097 16.2 1.4 2.8 2 0 0 2 2 2 2 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGC30171.1 - 0.0004 20.5 7.5 0.19 12.1 1.0 2.9 2 0 0 2 2 2 2 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGC30171.1 - 0.0026 17.8 18.3 0.096 12.8 1.1 3.6 2 1 1 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGC30171.1 - 1 9.3 5.9 2.2 8.3 0.3 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger PP-binding PF00550.20 EGC30172.1 - 3.9e-06 27.0 0.1 5.3e-05 23.4 0.1 2.0 1 1 0 1 1 1 1 Phosphopantetheine attachment site Fz PF01392.17 EGC30173.1 - 0.0019 18.5 3.9 0.0019 18.5 2.7 2.0 2 1 0 2 2 2 1 Fz domain RAM PF15320.1 EGC30173.1 - 9.1 6.6 17.8 7.4 6.9 11.2 1.6 2 0 0 2 2 2 0 mRNA cap methylation, RNMT-activating mini protein Ras PF00071.17 EGC30174.1 - 3.6e-52 176.0 0.0 1.3e-51 174.2 0.0 1.8 2 0 0 2 2 2 1 Ras family BTB PF00651.26 EGC30174.1 - 6.4e-32 109.8 3.0 4.3e-17 62.0 0.1 3.4 2 1 0 2 2 2 2 BTB/POZ domain Miro PF08477.8 EGC30174.1 - 1.6e-16 60.8 0.0 4e-16 59.5 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30174.1 - 6.5e-07 28.7 0.0 2.3e-05 23.7 0.0 2.3 2 0 0 2 2 2 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC30174.1 - 0.0095 15.3 0.0 0.03 13.7 0.0 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC30174.1 - 0.11 12.4 0.0 0.69 9.8 0.0 2.2 2 0 0 2 2 2 0 50S ribosome-binding GTPase LRR_4 PF12799.2 EGC30175.1 - 2.1e-27 94.2 62.3 8.2e-09 34.8 0.2 9.9 5 3 8 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30175.1 - 1.4e-18 66.3 52.9 4.6e-08 32.7 3.3 7.6 4 2 4 8 8 8 7 Leucine rich repeat LRR_6 PF13516.1 EGC30175.1 - 1.9e-18 64.4 39.8 0.033 14.2 0.0 13.0 12 2 0 12 12 12 7 Leucine Rich repeat LRR_1 PF00560.28 EGC30175.1 - 1.3e-10 39.8 42.7 0.036 14.0 0.9 12.5 12 2 1 13 13 13 5 Leucine Rich Repeat LRR_7 PF13504.1 EGC30175.1 - 1.4e-05 24.5 41.7 0.7 10.3 0.2 12.5 14 0 0 14 14 14 4 Leucine rich repeat LRR_2 PF07723.8 EGC30175.1 - 4.1 8.0 9.5 46 4.7 0.2 5.3 5 0 0 5 5 5 0 Leucine Rich Repeat DUF2305 PF10230.4 EGC30176.1 - 6.2e-56 189.7 0.3 7.3e-56 189.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2305) Abhydrolase_6 PF12697.2 EGC30176.1 - 2.6e-05 24.1 0.0 3.3e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC30176.1 - 6.9e-05 22.6 0.0 0.00014 21.6 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC30176.1 - 0.002 17.7 0.0 0.0044 16.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC30176.1 - 0.045 12.9 0.0 0.16 11.1 0.0 1.9 1 1 1 2 2 2 0 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGC30176.1 - 0.078 12.4 0.0 0.45 9.9 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Abhydrolase_6 PF12697.2 EGC30177.1 - 3.5e-21 76.1 0.0 4.3e-21 75.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC30177.1 - 5.5e-12 45.7 0.1 5.3e-11 42.5 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC30177.1 - 3.1e-11 43.2 0.0 6.1e-11 42.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGC30177.1 - 0.00054 19.4 0.0 0.019 14.4 0.0 2.3 2 0 0 2 2 2 1 Serine hydrolase (FSH1) DLH PF01738.13 EGC30177.1 - 0.018 14.3 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Hydrolase_4 PF12146.3 EGC30177.1 - 0.055 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Ndr PF03096.9 EGC30177.1 - 0.088 11.2 0.0 0.15 10.4 0.0 1.4 2 0 0 2 2 2 0 Ndr family Thioesterase PF00975.15 EGC30177.1 - 0.089 13.0 0.0 0.13 12.4 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain LRR_6 PF13516.1 EGC30178.1 - 9.6e-11 40.6 28.7 0.071 13.2 0.1 10.9 11 2 0 11 11 11 3 Leucine Rich repeat LRR_1 PF00560.28 EGC30178.1 - 7.4e-06 25.3 13.0 1.7 8.9 0.3 7.6 6 1 1 7 7 7 2 Leucine Rich Repeat LRR_7 PF13504.1 EGC30178.1 - 0.00016 21.3 5.9 20 5.9 0.0 7.1 7 0 0 7 7 7 1 Leucine rich repeat LRR_4 PF12799.2 EGC30178.1 - 0.00018 21.0 24.4 0.0062 16.1 0.4 6.6 4 2 3 7 7 7 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30178.1 - 0.011 15.4 16.2 16 5.3 1.0 6.4 4 2 2 6 6 6 0 Leucine rich repeat bZIP_Maf PF03131.12 EGC30180.1 - 4.3e-08 33.3 11.7 4.3e-08 33.3 8.1 2.0 2 0 0 2 2 2 1 bZIP Maf transcription factor bZIP_1 PF00170.16 EGC30180.1 - 3e-07 30.2 13.6 9.6e-07 28.6 9.4 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGC30180.1 - 0.0066 16.2 11.7 0.0066 16.2 8.1 2.3 2 1 0 2 2 2 1 Basic region leucine zipper DUF465 PF04325.8 EGC30180.1 - 1.1 9.0 5.5 0.34 10.6 0.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF465) L31 PF09784.4 EGC30180.1 - 4.3 7.4 12.1 0.58 10.2 3.9 2.5 2 1 1 3 3 3 0 Mitochondrial ribosomal protein L31 DUF972 PF06156.8 EGC30180.1 - 7.7 6.9 16.3 0.11 12.8 2.1 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF972) DUF1108 PF06531.6 EGC30181.1 - 0.0086 16.2 0.1 0.013 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1108) B PF02216.11 EGC30181.1 - 0.15 11.8 1.2 1.7 8.4 0.0 2.8 3 0 0 3 3 3 0 B domain Methyltransf_23 PF13489.1 EGC30182.1 - 1.1e-17 64.1 0.1 2.2e-17 63.2 0.0 1.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC30182.1 - 8.2e-16 58.3 4.4 2.1e-14 53.7 0.0 3.6 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC30182.1 - 1.8e-12 47.1 0.0 3.7e-12 46.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC30182.1 - 7.1e-10 39.1 0.0 1.6e-09 38.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC30182.1 - 2.2e-09 37.6 0.0 7.1e-09 36.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30182.1 - 2.6e-08 34.4 0.0 4.8e-08 33.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC30182.1 - 8.6e-07 28.3 0.0 3.1e-06 26.4 0.0 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family MTS PF05175.9 EGC30182.1 - 1e-05 24.9 0.0 2.1e-05 23.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC30182.1 - 3.5e-05 23.8 0.0 6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGC30182.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase CheR PF01739.13 EGC30182.1 - 0.0015 17.8 0.0 1.6 7.9 0.0 2.5 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain DUF938 PF06080.7 EGC30182.1 - 0.0064 16.0 0.0 0.0099 15.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) RrnaAD PF00398.15 EGC30182.1 - 0.013 14.5 0.0 0.025 13.6 0.0 1.5 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase Methyltransf_4 PF02390.12 EGC30182.1 - 0.049 12.6 0.0 0.049 12.6 0.0 2.8 3 1 0 3 3 3 0 Putative methyltransferase RhoGEF PF00621.15 EGC30183.1 - 6.5e-33 114.1 7.6 6.5e-33 114.1 5.3 3.0 3 0 0 3 3 3 1 RhoGEF domain FYVE PF01363.16 EGC30183.1 - 2e-20 72.4 7.1 4.3e-20 71.3 4.9 1.6 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGC30183.1 - 4.1e-10 39.7 0.6 4.1e-10 39.7 0.4 2.8 2 1 1 3 3 3 1 PH domain FYVE_2 PF02318.11 EGC30183.1 - 0.00074 19.4 3.7 0.00074 19.4 2.5 2.5 3 0 0 3 3 3 1 FYVE-type zinc finger PH_11 PF15413.1 EGC30183.1 - 1.5 9.0 8.9 0.21 11.8 0.5 3.1 2 1 0 2 2 2 0 Pleckstrin homology domain Pex14_N PF04695.8 EGC30184.1 - 5.9 6.9 7.8 65 3.5 3.3 3.3 3 2 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPSF73-100_C PF11718.3 EGC30185.1 - 1.3e-40 139.0 10.4 1.3e-40 139.0 7.2 2.6 3 1 0 3 3 3 1 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Beta-Casp PF10996.3 EGC30185.1 - 3.2e-30 104.6 0.0 1e-29 103.0 0.0 1.9 1 0 0 1 1 1 1 Beta-Casp domain Lactamase_B PF00753.22 EGC30185.1 - 7.3e-15 55.1 0.3 1.8e-14 53.8 0.2 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC30185.1 - 1.3e-13 50.9 0.2 1.5e-12 47.4 0.1 2.3 2 0 0 2 2 2 1 Beta-lactamase superfamily domain RMMBL PF07521.7 EGC30185.1 - 1.3e-09 37.7 0.1 2.7e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 RNA-metabolising metallo-beta-lactamase Lactamase_B_3 PF13483.1 EGC30185.1 - 8.7e-07 28.7 0.0 4.9e-06 26.3 0.0 2.3 1 1 0 1 1 1 1 Beta-lactamase superfamily domain CPW_WPC PF09717.5 EGC30186.1 - 0.00079 20.0 20.9 12 6.6 0.2 5.7 1 1 1 2 2 2 1 Plasmodium falciparum domain of unknown function (CPW_WPC) Response_reg PF00072.19 EGC30187.1 - 9.1e-28 96.5 0.0 4.3e-19 68.5 0.0 2.7 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EGC30187.1 - 4.4e-19 68.2 0.6 4.7e-18 64.9 0.1 2.6 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGC30187.1 - 5.2e-13 48.7 0.3 5.2e-13 48.7 0.2 1.9 2 0 0 2 2 2 1 His Kinase A (phospho-acceptor) domain Nucleoporin_FG PF13634.1 EGC30189.1 - 1e-07 32.1 79.9 0.036 14.2 23.4 3.4 1 1 2 3 3 3 3 Nucleoporin FG repeat region FliW PF02623.10 EGC30189.1 - 0.071 12.6 1.5 0.65 9.5 1.0 2.3 1 1 0 1 1 1 0 FliW protein Arginase PF00491.16 EGC30191.1 - 3.4e-17 62.6 0.0 2.7e-16 59.7 0.0 1.8 2 0 0 2 2 2 1 Arginase family Arm PF00514.18 EGC30192.1 - 0.0013 18.4 0.5 9.9 6.1 0.0 4.5 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat Vac14_Fab1_bd PF12755.2 EGC30192.1 - 0.0024 18.1 1.3 0.18 12.2 0.1 2.8 2 0 0 2 2 2 1 Vacuolar 14 Fab1-binding region BTB PF00651.26 EGC30192.1 - 0.0038 17.1 4.0 0.016 15.1 0.3 3.2 2 1 1 3 3 3 1 BTB/POZ domain HEAT PF02985.17 EGC30192.1 - 0.11 12.5 0.0 76 3.7 0.0 3.9 4 0 0 4 4 4 0 HEAT repeat T4SS PF07996.6 EGC30192.1 - 1.3 8.8 10.1 0.12 12.2 2.4 2.4 2 0 0 2 2 2 0 Type IV secretion system proteins Kelch_3 PF13415.1 EGC30194.1 - 3.3e-39 132.1 5.4 1.2e-08 34.8 0.0 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC30194.1 - 2.1e-35 120.2 18.2 3e-10 39.6 0.0 7.0 5 1 2 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC30194.1 - 9.2e-33 111.5 12.1 7.3e-08 31.8 0.0 7.3 6 2 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC30194.1 - 6.6e-30 102.0 16.6 1.1e-07 31.7 0.0 6.7 3 2 4 7 7 7 6 Kelch motif Kelch_5 PF13854.1 EGC30194.1 - 7.1e-20 70.5 16.3 2.2e-05 24.2 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC30194.1 - 1.1e-16 59.8 9.9 0.0052 16.5 0.0 6.2 6 0 0 6 6 6 5 Kelch motif F-box-like PF12937.2 EGC30194.1 - 3.5e-06 26.6 0.2 8.3e-06 25.4 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC30194.1 - 0.025 14.2 0.2 0.052 13.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain Peptidase_M41 PF01434.13 EGC30195.1 - 3.6e-71 239.0 0.2 5.6e-71 238.3 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGC30195.1 - 3.1e-42 143.8 0.0 6.6e-42 142.8 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC30195.1 - 0.00017 21.3 0.3 0.0019 17.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) Zeta_toxin PF06414.7 EGC30195.1 - 0.00035 19.7 0.1 0.0013 17.9 0.0 1.9 2 0 0 2 2 2 1 Zeta toxin AAA_25 PF13481.1 EGC30195.1 - 0.0012 18.3 1.0 0.012 14.9 0.2 2.5 1 1 1 2 2 2 1 AAA domain RuvB_N PF05496.7 EGC30195.1 - 0.0012 17.8 0.0 0.0025 16.9 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC30195.1 - 0.0021 18.2 1.3 0.11 12.6 0.1 3.0 3 1 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EGC30195.1 - 0.0024 18.6 2.9 0.0054 17.5 0.0 2.9 2 2 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGC30195.1 - 0.0024 17.7 0.0 0.016 15.0 0.0 2.2 2 0 0 2 2 2 1 AAA domain TIP49 PF06068.8 EGC30195.1 - 0.0088 14.8 0.1 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_16 PF13191.1 EGC30195.1 - 0.011 15.6 0.7 0.3 11.0 0.1 3.1 2 2 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EGC30195.1 - 0.013 14.9 0.0 0.024 14.0 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGC30195.1 - 0.021 14.5 2.8 0.024 14.3 0.6 2.0 2 0 0 2 2 2 0 Part of AAA domain AAA_33 PF13671.1 EGC30195.1 - 0.021 14.6 0.1 0.073 12.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC30195.1 - 0.075 13.3 9.9 0.42 10.9 0.0 3.6 3 1 0 3 3 2 0 AAA domain AAA_11 PF13086.1 EGC30195.1 - 0.076 12.5 2.6 11 5.5 0.0 2.3 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EGC30195.1 - 0.099 11.7 0.3 0.26 10.4 0.2 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIG PF01833.19 EGC30197.1 - 6e-06 26.1 0.8 1.4e-05 25.0 0.5 1.7 1 0 0 1 1 1 1 IPT/TIG domain Regulator_TrmB PF11495.3 EGC30198.1 - 0.11 11.4 0.3 0.13 11.2 0.2 1.0 1 0 0 1 1 1 0 Archaeal transcriptional regulator TrmB Arf PF00025.16 EGC30199.1 - 2.6e-60 202.6 0.4 3e-60 202.4 0.3 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC30199.1 - 1.3e-12 47.3 0.0 1.6e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC30199.1 - 5.9e-11 41.9 0.1 7.5e-11 41.5 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC30199.1 - 2.5e-09 37.6 0.0 3.5e-09 37.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EGC30199.1 - 1.3e-05 24.0 0.7 0.00032 19.4 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit Gtr1_RagA PF04670.7 EGC30199.1 - 1.9e-05 23.9 0.1 2.4e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC30199.1 - 2.5e-05 24.1 0.2 3.4e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC30199.1 - 9.7e-05 21.8 0.4 0.011 15.1 0.0 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC30199.1 - 0.0026 17.9 0.3 0.0053 16.8 0.2 1.6 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EGC30199.1 - 0.0046 16.8 0.3 0.018 14.9 0.2 1.8 1 1 1 2 2 2 1 AAA domain SRP54 PF00448.17 EGC30199.1 - 0.034 13.5 0.1 0.13 11.7 0.0 1.8 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain ABC_tran PF00005.22 EGC30199.1 - 0.051 13.8 0.2 0.093 13.0 0.2 1.5 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EGC30199.1 - 0.086 12.7 0.1 0.12 12.2 0.0 1.4 1 1 0 1 1 1 0 AAA domain UPF0147 PF03685.8 EGC30200.1 - 0.012 15.5 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Copine PF07002.11 EGC30201.1 - 1.2e-43 148.4 0.2 1.6e-43 147.9 0.2 1.2 1 0 0 1 1 1 1 Copine vWA-TerF-like PF10138.4 EGC30201.1 - 1.1e-14 54.7 0.0 1.4e-14 54.4 0.0 1.2 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EGC30201.1 - 0.00022 21.3 0.0 0.00034 20.7 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain Chordopox_A13L PF05961.6 EGC30203.1 - 0.88 9.5 6.1 0.24 11.3 1.7 2.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein Baculo_11_kDa PF06143.6 EGC30203.1 - 0.99 8.8 4.6 13 5.2 0.5 2.2 2 0 0 2 2 2 0 Baculovirus 11 kDa family Adipogenin PF15202.1 EGC30204.1 - 0.039 13.8 0.2 0.039 13.8 0.1 2.1 2 0 0 2 2 2 0 Adipogenin EamA PF00892.15 EGC30204.1 - 0.067 13.2 14.0 3.6 7.6 5.6 3.1 3 0 0 3 3 3 0 EamA-like transporter family Claudin_3 PF06653.6 EGC30204.1 - 2.5 7.8 13.9 8.9 6.0 0.0 2.5 3 0 0 3 3 3 0 Tight junction protein, Claudin-like ATP-synt_8 PF00895.15 EGC30205.1 - 0.03 14.5 0.8 0.03 14.5 0.6 3.1 1 1 2 3 3 3 0 ATP synthase protein 8 CDC27 PF09507.5 EGC30205.1 - 4.8 6.2 9.1 6.2 5.9 6.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF3328 PF11807.3 EGC30205.1 - 5.4 6.6 5.8 0.45 10.1 0.2 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) Kelch_6 PF13964.1 EGC30206.1 - 3.6e-11 42.7 5.4 0.0014 18.7 0.0 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_1 PF01344.20 EGC30206.1 - 4.1e-11 42.2 11.7 0.0032 16.9 0.0 5.1 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EGC30206.1 - 1.1e-06 28.5 2.9 2.5 8.3 0.1 5.4 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC30206.1 - 0.00097 19.0 10.5 2 8.4 0.0 5.0 5 0 0 5 5 5 2 Kelch motif Kelch_4 PF13418.1 EGC30206.1 - 0.011 15.4 11.1 0.21 11.3 0.1 4.7 4 1 1 5 5 5 0 Galactose oxidase, central domain Kelch_2 PF07646.10 EGC30206.1 - 0.046 13.5 7.1 4.3 7.2 0.0 4.3 5 0 0 5 5 5 0 Kelch motif Macoilin PF09726.4 EGC30208.1 - 0.0004 18.8 23.4 0.0004 18.8 16.2 2.0 2 0 0 2 2 2 1 Transmembrane protein Period_C PF12114.3 EGC30208.1 - 0.32 10.5 13.6 1 8.9 9.4 1.8 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PUA PF01472.15 EGC30209.1 - 2.2e-16 59.3 0.3 4e-16 58.4 0.2 1.5 1 0 0 1 1 1 1 PUA domain FNIP PF05725.7 EGC30210.1 - 1.4e-55 184.9 110.6 1.1e-10 41.2 4.7 13.1 6 4 7 13 13 13 11 FNIP Repeat Pkinase PF00069.20 EGC30210.1 - 2.2e-46 158.1 0.4 3.1e-46 157.6 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30210.1 - 3.8e-31 108.0 0.0 5.6e-31 107.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC30210.1 - 0.00078 18.4 0.0 0.0014 17.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC30210.1 - 0.015 15.0 0.0 0.023 14.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGC30210.1 - 0.021 14.1 0.0 0.037 13.3 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGC30210.1 - 0.026 13.5 0.0 0.039 13.0 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGC30210.1 - 0.045 13.3 0.3 0.086 12.4 0.2 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase FNIP PF05725.7 EGC30211.1 - 5.4e-62 205.4 134.0 1.4e-11 44.1 0.6 13.1 8 3 7 15 15 15 14 FNIP Repeat Pkinase PF00069.20 EGC30211.1 - 7.6e-47 159.6 1.0 4.8e-46 157.0 0.7 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30211.1 - 3.6e-30 104.8 0.0 1.7e-29 102.6 0.0 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC30211.1 - 0.00011 21.2 0.0 0.0002 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGC30211.1 - 0.0068 15.7 0.0 0.012 14.9 0.0 1.3 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL APH PF01636.18 EGC30211.1 - 0.013 15.1 0.0 0.02 14.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC30211.1 - 0.036 13.1 0.0 0.055 12.5 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGC30211.1 - 0.05 13.1 0.5 0.1 12.1 0.3 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase PRKCSH_1 PF13015.1 EGC30213.1 - 0.059 12.8 0.8 0.12 11.8 0.5 1.6 1 1 0 1 1 1 0 Glucosidase II beta subunit-like protein Cyclin PF08613.6 EGC30214.1 - 1.9e-29 103.0 3.1 1.9e-29 103.0 2.1 4.5 4 2 0 4 4 4 1 Cyclin Cyclin_N PF00134.18 EGC30214.1 - 3.5e-09 36.3 0.1 3.5e-09 36.3 0.0 3.5 3 1 0 3 3 3 1 Cyclin, N-terminal domain Autophagy_Cterm PF10381.4 EGC30215.1 - 0.44 9.7 2.8 12 5.1 0.3 2.5 2 0 0 2 2 2 0 Autophagocytosis associated protein C-terminal Utp14 PF04615.8 EGC30216.1 - 0.0042 15.3 36.9 0.0045 15.2 25.6 1.0 1 0 0 1 1 1 1 Utp14 protein MPP6 PF10175.4 EGC30216.1 - 0.043 14.2 22.6 0.025 14.9 11.1 3.0 1 1 2 3 3 3 0 M-phase phosphoprotein 6 Serinc PF03348.10 EGC30216.1 - 1.4 7.5 0.0 1.4 7.5 0.0 2.4 1 1 1 2 2 2 0 Serine incorporator (Serinc) Hid1 PF12722.2 EGC30216.1 - 6.4 4.3 20.8 6.7 4.2 14.4 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein DUF3546 PF12066.3 EGC30217.1 - 4.7e-21 74.8 11.2 4.7e-21 74.8 7.8 3.4 3 0 0 3 3 3 1 Domain of unknown function (DUF3546) ARS2 PF04959.8 EGC30217.1 - 1e-13 52.0 0.4 1e-13 52.0 0.3 3.7 5 0 0 5 5 5 1 Arsenite-resistance protein 2 DUF4187 PF13821.1 EGC30217.1 - 2.3e-08 33.4 1.5 2.3e-08 33.4 1.0 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4187) RRM_1 PF00076.17 EGC30217.1 - 3.7e-05 23.2 0.0 0.00012 21.6 0.0 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C2H2_4 PF13894.1 EGC30217.1 - 0.11 12.9 0.3 0.11 12.9 0.2 2.6 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_2 PF12756.2 EGC30217.1 - 0.12 12.5 8.8 0.14 12.2 1.1 3.2 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGC30217.1 - 1.4 9.1 11.5 1.2 9.3 0.7 2.6 2 0 0 2 2 2 0 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGC30217.1 - 1.5 9.3 11.1 0.049 13.9 0.6 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Dicty_spore_N PF04562.7 EGC30218.1 - 2e-22 79.7 27.0 2e-22 79.7 18.7 5.4 3 2 2 5 5 5 2 Dictyostelium spore coat protein, N terminus PPR_2 PF13041.1 EGC30219.1 - 0.0012 18.7 0.8 0.12 12.3 0.0 4.2 5 0 0 5 5 5 1 PPR repeat family PPR PF01535.15 EGC30219.1 - 0.0064 16.3 1.7 3.1 7.9 0.0 4.2 5 0 0 5 5 5 1 PPR repeat PPR_3 PF13812.1 EGC30219.1 - 0.065 13.5 0.0 4.5 7.8 0.0 3.0 2 0 0 2 2 2 0 Pentatricopeptide repeat domain Gly_kinase PF02595.10 EGC30221.1 - 4.4e-66 223.1 0.0 5.4e-66 222.8 0.0 1.0 1 0 0 1 1 1 1 Glycerate kinase family OmpH PF03938.9 EGC30222.1 - 0.00057 19.8 0.0 0.00057 19.8 0.0 5.9 4 1 2 6 6 6 1 Outer membrane protein (OmpH-like) Ribosomal_S27e PF01667.12 EGC30223.1 - 3.2e-24 84.2 3.0 4e-24 83.9 2.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S27 Tmemb_55A PF09788.4 EGC30223.1 - 0.0014 17.8 0.3 0.0016 17.6 0.2 1.0 1 0 0 1 1 1 1 Transmembrane protein 55A IBR PF01485.16 EGC30223.1 - 0.0059 16.4 0.6 0.0087 15.9 0.4 1.2 1 0 0 1 1 1 1 IBR domain DUF2318 PF10080.4 EGC30223.1 - 0.028 14.2 0.1 0.028 14.1 0.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) zf-LSD1 PF06943.7 EGC30223.1 - 0.043 13.4 3.6 0.19 11.3 0.7 2.5 2 1 1 3 3 3 0 LSD1 zinc finger DUF3795 PF12675.2 EGC30223.1 - 0.14 12.3 1.4 0.49 10.6 0.5 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3795) zf-CHY PF05495.7 EGC30223.1 - 0.2 11.8 2.0 0.34 11.1 1.4 1.4 1 1 0 1 1 1 0 CHY zinc finger Yippee-Mis18 PF03226.9 EGC30223.1 - 0.27 11.3 2.3 4.4 7.4 0.1 2.1 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly zinc_ribbon_4 PF13717.1 EGC30223.1 - 0.47 10.1 2.7 13 5.5 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGC30223.1 - 0.56 9.8 2.7 11 5.6 1.9 2.3 1 1 0 1 1 1 0 zinc-ribbon domain DUF2012 PF09430.5 EGC30224.1 - 4.2e-13 49.2 0.1 6.1e-13 48.6 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2012) MIT PF04212.13 EGC30225.1 - 5.7e-11 42.1 1.0 1.5e-10 40.8 0.7 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain Mod_r PF07200.8 EGC30225.1 - 0.0039 17.1 5.4 0.0039 17.1 3.7 3.3 3 1 0 3 3 3 2 Modifier of rudimentary (Mod(r)) protein Kinesin-relat_1 PF12711.2 EGC30225.1 - 0.03 14.7 13.4 0.21 11.9 0.3 3.3 3 0 0 3 3 3 0 Kinesin motor IncA PF04156.9 EGC30225.1 - 0.05 13.1 13.8 0.69 9.4 2.7 2.6 2 0 0 2 2 2 0 IncA protein HALZ PF02183.13 EGC30225.1 - 0.063 13.0 0.5 0.063 13.0 0.3 2.3 2 0 0 2 2 2 0 Homeobox associated leucine zipper zf-ZPR1 PF03367.8 EGC30225.1 - 0.32 10.1 5.5 0.089 11.9 0.7 2.1 1 1 1 2 2 2 0 ZPR1 zinc-finger domain ETF_QO PF05187.8 EGC30226.1 - 1.8 8.5 4.6 1 9.3 1.3 2.0 1 1 0 1 1 1 0 Electron transfer flavoprotein-ubiquinone oxidoreductase FH2 PF02181.18 EGC30227.1 - 3e-60 204.0 2.4 6.2e-60 203.0 1.7 1.5 1 0 0 1 1 1 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGC30227.1 - 0.0004 19.7 0.0 0.0004 19.7 0.0 2.0 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Ank_2 PF12796.2 EGC30229.1 - 1.5e-33 114.9 5.0 6.5e-19 68.0 0.8 2.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC30229.1 - 2e-28 96.7 0.4 2.2e-09 36.6 0.0 3.6 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGC30229.1 - 4.9e-23 80.6 1.0 8.4e-09 35.3 0.1 2.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC30229.1 - 1.9e-18 66.4 0.9 5.8e-08 33.0 0.1 3.3 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC30229.1 - 1.2e-15 56.0 1.8 6.3e-06 25.9 0.1 3.9 4 0 0 4 4 4 3 Ankyrin repeat Lipoprotein_3 PF00938.12 EGC30229.1 - 0.057 13.1 0.3 0.14 11.9 0.2 1.7 1 0 0 1 1 1 0 Lipoprotein Shigella_OspC PF06128.6 EGC30229.1 - 0.08 12.4 1.4 1.4 8.3 0.1 2.1 2 0 0 2 2 2 0 Shigella flexneri OspC protein Sec23_helical PF04815.10 EGC30230.1 - 0.037 13.4 0.2 0.099 12.0 0.0 1.8 2 0 0 2 2 2 0 Sec23/Sec24 helical domain VRP1 PF03538.9 EGC30230.1 - 0.087 11.8 0.2 0.45 9.5 0.0 1.9 1 1 1 2 2 2 0 Salmonella virulence plasmid 28.1kDa A protein 7TMR-DISM_7TM PF07695.6 EGC30231.1 - 0.17 11.5 9.6 1.7 8.2 5.8 2.0 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2953 PF11167.3 EGC30231.1 - 3.7 7.5 5.4 1.9 8.4 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2953) DUF4131 PF13567.1 EGC30231.1 - 7 6.0 7.6 8.7 5.7 0.7 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) eIF3_subunit PF08597.5 EGC30232.1 - 2.2e-44 151.8 25.4 2.9e-44 151.5 17.6 1.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit polyprenyl_synt PF00348.12 EGC30232.1 - 0.072 11.9 3.8 0.14 10.9 2.6 1.4 1 0 0 1 1 1 0 Polyprenyl synthetase PAXIP1_C PF15364.1 EGC30232.1 - 0.96 9.3 15.2 0.17 11.7 7.8 1.8 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein DEAD PF00270.24 EGC30233.1 - 1.8e-49 167.4 0.0 1.4e-45 154.8 0.0 2.3 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC30233.1 - 1.4e-26 92.1 0.4 1.1e-25 89.2 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC30233.1 - 4e-05 23.5 3.3 9.9e-05 22.2 0.0 2.9 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit OTU PF02338.14 EGC30234.1 - 4.7e-14 53.0 0.1 6.4e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease adh_short PF00106.20 EGC30235.1 - 1.1e-17 64.4 0.0 2.1e-17 63.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC30235.1 - 5.1e-08 32.9 0.1 1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC30235.1 - 5.3e-08 32.7 0.0 8.8e-08 32.0 0.0 1.3 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC30235.1 - 1.1e-05 25.0 0.0 1.4e-05 24.6 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC30235.1 - 0.00063 19.8 0.1 0.0061 16.5 0.1 2.3 1 1 0 1 1 1 1 NADH(P)-binding 7tm_2 PF00002.19 EGC30236.1 - 1.9e-09 36.9 20.2 1.5e-08 34.0 14.0 2.0 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGC30236.1 - 0.00036 19.5 17.5 0.00036 19.5 12.1 3.1 2 1 1 3 3 3 1 Slime mold cyclic AMP receptor Frizzled PF01534.12 EGC30236.1 - 0.11 11.2 12.5 0.54 8.9 8.7 2.0 1 1 0 1 1 1 0 Frizzled/Smoothened family membrane region U3_assoc_6 PF08640.6 EGC30237.1 - 5.2e-21 74.1 5.9 4.4e-20 71.2 2.3 3.2 3 0 0 3 3 3 1 U3 small nucleolar RNA-associated protein 6 TPR_14 PF13428.1 EGC30237.1 - 0.014 15.9 0.0 11 7.0 0.0 3.7 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC30237.1 - 0.083 12.5 0.4 5.7 6.6 0.0 3.4 3 0 0 3 3 3 0 TPR repeat ABC2_membrane_3 PF12698.2 EGC30238.1 - 0.16 11.0 4.8 0.16 11.0 3.4 1.0 1 0 0 1 1 1 0 ABC-2 family transporter protein Apis_Csd PF11671.3 EGC30238.1 - 2.1 8.1 8.9 2.4 7.9 6.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein Solute_trans_a PF03619.11 EGC30239.1 - 5.2e-100 334.2 16.5 6.4e-100 333.9 11.5 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha TRAP_beta PF05753.9 EGC30239.1 - 0.069 12.3 0.1 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Translocon-associated protein beta (TRAPB) MRP-S28 PF10213.4 EGC30240.1 - 9.6e-11 41.8 0.7 9.6e-11 41.8 0.5 2.6 2 0 0 2 2 2 1 Mitochondrial ribosomal subunit protein RabGAP-TBC PF00566.13 EGC30241.1 - 4.9e-27 94.7 4.6 4.9e-27 94.7 3.2 2.5 2 1 0 2 2 2 1 Rab-GTPase-TBC domain IncA PF04156.9 EGC30241.1 - 0.0061 16.1 13.9 0.014 14.9 9.6 1.8 1 0 0 1 1 1 1 IncA protein ADIP PF11559.3 EGC30241.1 - 3 7.7 22.4 1.8 8.4 12.6 2.4 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding EF-hand_1 PF00036.27 EGC30242.1 - 3.5e-41 135.3 13.0 4.4e-10 38.1 0.0 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC30242.1 - 1.2e-37 127.8 3.6 5.9e-21 74.3 0.4 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC30242.1 - 2.6e-34 116.6 11.2 6.1e-17 60.9 0.3 4.1 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_6 PF13405.1 EGC30242.1 - 2.1e-30 101.8 7.3 9.2e-10 37.5 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC30242.1 - 5.4e-27 91.9 9.5 4.1e-07 29.0 0.0 4.3 4 0 0 4 4 4 4 EF hand EF-hand_9 PF14658.1 EGC30242.1 - 1.7e-13 50.2 0.0 7.5e-08 32.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain SPARC_Ca_bdg PF10591.4 EGC30242.1 - 1.4e-09 37.9 0.0 0.00028 20.8 0.0 2.1 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGC30242.1 - 5.9e-09 35.5 0.7 0.00087 18.9 0.1 2.3 1 1 1 2 2 2 2 Cytoskeletal-regulatory complex EF hand UPF0154 PF03672.8 EGC30242.1 - 3.3e-06 26.6 0.6 0.16 11.6 0.0 3.3 3 1 1 4 4 3 2 Uncharacterised protein family (UPF0154) EFhand_Ca_insen PF08726.5 EGC30242.1 - 1.6e-05 24.7 0.7 0.00021 21.2 0.1 2.4 2 2 0 2 2 2 1 Ca2+ insensitive EF hand Caleosin PF05042.8 EGC30242.1 - 0.00098 18.7 0.2 0.084 12.4 0.1 2.7 1 1 0 1 1 1 1 Caleosin related protein EF-hand_like PF09279.6 EGC30242.1 - 0.0011 18.9 1.2 0.012 15.5 0.1 2.5 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like DUF1103 PF06513.6 EGC30242.1 - 0.0016 17.8 3.0 0.0017 17.8 1.7 1.3 1 1 0 1 1 1 1 Repeat of unknown function (DUF1103) TerB PF05099.8 EGC30242.1 - 0.0017 18.0 0.5 0.55 9.9 0.0 2.3 1 1 1 2 2 2 2 Tellurite resistance protein TerB RNA_pol_Rpb4 PF03874.11 EGC30242.1 - 0.014 15.3 1.2 3.3 7.7 0.1 2.7 3 0 0 3 3 3 0 RNA polymerase Rpb4 MotA_activ PF09114.5 EGC30242.1 - 0.023 14.4 0.2 3.2 7.5 0.0 2.4 2 0 0 2 2 2 0 Transcription factor MotA, activation domain Toprim_2 PF13155.1 EGC30242.1 - 0.037 14.3 0.6 9.1 6.6 0.0 2.6 1 1 0 2 2 2 0 Toprim-like Acetyltransf_11 PF13720.1 EGC30242.1 - 0.061 13.5 0.1 6.2 7.1 0.0 2.2 2 0 0 2 2 2 0 Udp N-acetylglucosamine O-acyltransferase; Domain 2 SapB_1 PF05184.10 EGC30242.1 - 0.061 13.1 2.9 0.53 10.1 0.0 2.9 4 0 0 4 4 3 0 Saposin-like type B, region 1 Tenui_NCP PF04876.7 EGC30242.1 - 0.064 12.8 0.1 0.67 9.4 0.0 2.0 1 1 1 2 2 2 0 Tenuivirus major non-capsid protein Poly_export PF02563.11 EGC30242.1 - 0.072 12.8 0.0 1.4 8.6 0.0 2.7 2 1 1 3 3 3 0 Polysaccharide biosynthesis/export protein SusE PF14292.1 EGC30242.1 - 0.078 12.7 0.4 1.1 9.0 0.0 2.2 2 0 0 2 2 2 0 SusE outer membrane protein LNS2 PF08235.8 EGC30242.1 - 0.095 12.2 0.0 1.2 8.7 0.0 2.0 1 1 0 2 2 2 0 LNS2 (Lipin/Ned1/Smp2) DUF853 PF05872.7 EGC30242.1 - 0.11 10.8 0.1 1.5 7.0 0.0 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF853) VCBS PF13517.1 EGC30242.1 - 8.6 6.8 6.4 68 3.9 2.4 2.6 1 1 1 2 2 2 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella D-ser_dehydrat PF14031.1 EGC30243.1 - 1.6e-18 66.6 0.0 4.6e-18 65.2 0.0 1.8 2 0 0 2 2 2 1 Putative serine dehydratase domain Ala_racemase_N PF01168.15 EGC30243.1 - 6e-10 39.0 0.0 8.6e-10 38.5 0.0 1.1 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain DWNN PF08783.6 EGC30244.1 - 2.5e-26 91.4 0.6 9e-26 89.6 0.4 2.1 1 0 0 1 1 1 1 DWNN domain zf-CCHC_2 PF13696.1 EGC30244.1 - 1.9e-09 36.8 6.2 5.2e-09 35.4 4.3 1.8 1 0 0 1 1 1 1 Zinc knuckle DUF3246 PF11596.3 EGC30244.1 - 0.015 14.5 10.3 0.61 9.3 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3246) zf-CCHC_3 PF13917.1 EGC30244.1 - 1.7 8.4 8.0 0.097 12.4 0.9 2.3 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC PF00098.18 EGC30244.1 - 2.2 8.3 10.4 0.055 13.4 1.3 2.4 2 0 0 2 2 2 0 Zinc knuckle Guanylate_kin PF00625.16 EGC30245.1 - 1.2e-56 191.0 0.0 1.3e-56 190.9 0.0 1.0 1 0 0 1 1 1 1 Guanylate kinase AAA_18 PF13238.1 EGC30245.1 - 6.8e-08 32.8 0.1 1.6e-07 31.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC30245.1 - 1.1e-06 28.5 0.0 1.8e-06 27.9 0.0 1.3 1 0 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGC30245.1 - 2.8e-06 27.2 0.0 8.3e-05 22.5 0.0 2.0 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC30245.1 - 4.5e-05 22.7 0.0 0.00016 20.8 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGC30245.1 - 7.8e-05 23.4 0.2 0.00011 22.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGC30245.1 - 0.00046 20.4 0.0 0.00059 20.1 0.0 1.4 1 1 0 1 1 1 1 ABC transporter AAA_16 PF13191.1 EGC30245.1 - 0.00077 19.5 0.1 0.0018 18.3 0.0 1.6 1 1 0 2 2 2 1 AAA ATPase domain NTPase_1 PF03266.10 EGC30245.1 - 0.0056 16.4 0.1 0.0097 15.6 0.1 1.6 1 1 0 1 1 1 1 NTPase AAA_29 PF13555.1 EGC30245.1 - 0.0064 16.0 0.0 0.011 15.1 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC30245.1 - 0.0067 16.5 0.0 0.013 15.6 0.0 1.6 2 1 0 2 2 2 1 AAA domain ADK PF00406.17 EGC30245.1 - 0.012 15.4 0.1 3.7 7.3 0.0 2.5 2 1 0 2 2 2 0 Adenylate kinase AAA_5 PF07728.9 EGC30245.1 - 0.016 14.9 0.1 0.56 9.9 0.0 2.5 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) ArgK PF03308.11 EGC30245.1 - 0.021 13.6 0.0 0.03 13.0 0.0 1.3 1 0 0 1 1 1 0 ArgK protein AAA_28 PF13521.1 EGC30245.1 - 0.049 13.5 0.0 0.091 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGC30245.1 - 0.079 13.1 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 RNA helicase cobW PF02492.14 EGC30245.1 - 0.082 12.3 0.1 5.1 6.4 0.0 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EGC30245.1 - 0.1 12.5 0.0 0.2 11.5 0.0 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGC30245.1 - 0.11 12.6 0.0 0.27 11.4 0.0 1.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Trehalase PF01204.13 EGC30247.1 - 1.4e-143 479.2 1.3 1.6e-143 479.0 0.9 1.0 1 0 0 1 1 1 1 Trehalase GDE_C PF06202.9 EGC30247.1 - 6.4e-05 21.8 7.7 0.00049 18.9 5.3 1.9 1 1 0 1 1 1 1 Amylo-alpha-1,6-glucosidase Pkinase_Tyr PF07714.12 EGC30248.1 - 1.8e-58 197.6 0.0 2.1e-58 197.4 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30248.1 - 2.8e-57 193.8 0.0 3.5e-57 193.4 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC30248.1 - 0.00039 19.4 0.0 0.00079 18.4 0.0 1.4 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC30248.1 - 0.0012 18.5 0.1 0.0023 17.6 0.1 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC30248.1 - 0.0017 17.4 0.0 0.0028 16.7 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC30248.1 - 0.018 14.3 0.2 0.032 13.5 0.0 1.5 2 0 0 2 2 2 0 RIO1 family zf-UBR PF02207.15 EGC30249.1 - 1.3e-18 66.4 6.5 1.3e-18 66.4 4.5 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) Acyl_transf_1 PF00698.16 EGC30250.1 - 1e-22 80.8 0.0 1.1e-22 80.7 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain Dicty_spore_N PF04562.7 EGC30251.1 - 9.5e-30 103.3 20.3 9.5e-30 103.3 14.1 5.8 3 1 2 5 5 5 1 Dictyostelium spore coat protein, N terminus RPN7 PF10602.4 EGC30252.1 - 1.9e-54 183.7 0.3 3.7e-54 182.7 0.2 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGC30252.1 - 3.5e-18 65.8 0.8 1e-17 64.3 0.2 2.1 2 0 0 2 2 2 1 PCI domain TPR_1 PF00515.23 EGC30252.1 - 0.0055 16.2 2.0 0.012 15.2 0.1 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC30252.1 - 0.011 15.5 1.9 0.057 13.3 0.0 3.0 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC30252.1 - 0.06 13.2 0.0 0.15 11.9 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC30252.1 - 0.065 13.0 0.1 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC30252.1 - 0.079 12.7 0.7 0.31 10.9 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC30252.1 - 0.085 12.5 0.1 0.51 10.0 0.0 2.4 3 0 0 3 3 3 0 TPR repeat Calreticulin PF00262.13 EGC30253.1 - 1.9e-105 352.5 19.1 1.9e-105 352.5 13.2 1.9 2 0 0 2 2 2 1 Calreticulin family AAA_23 PF13476.1 EGC30253.1 - 0.82 9.9 19.8 1.6 9.0 13.7 1.5 1 0 0 1 1 1 0 AAA domain Nuc-transf PF10127.4 EGC30254.1 - 8.3e-33 113.7 2.5 2.6e-21 76.0 0.1 2.2 2 0 0 2 2 2 2 Predicted nucleotidyltransferase Ras PF00071.17 EGC30255.1 - 2.4e-50 170.1 0.9 3e-50 169.7 0.6 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30255.1 - 9.6e-16 58.3 0.2 1.6e-15 57.6 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30255.1 - 4.9e-09 35.6 0.1 6.2e-09 35.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC30255.1 - 5.2e-09 35.7 0.0 7.4e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC30255.1 - 7e-06 25.3 0.2 1.1e-05 24.7 0.2 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC30255.1 - 0.00034 20.5 0.0 0.00072 19.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC30255.1 - 0.0025 17.0 0.1 0.019 14.2 0.0 2.0 2 0 0 2 2 2 1 Ferrous iron transport protein B Gtr1_RagA PF04670.7 EGC30255.1 - 0.0033 16.5 0.1 0.0048 16.0 0.1 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_24 PF13479.1 EGC30255.1 - 0.0055 16.3 0.3 0.0074 15.9 0.2 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC30255.1 - 0.0056 17.5 1.1 2 9.2 0.2 2.4 2 1 0 2 2 2 2 AAA domain PRK PF00485.13 EGC30255.1 - 0.014 15.0 0.0 0.025 14.1 0.0 1.4 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family ATP_bind_1 PF03029.12 EGC30255.1 - 0.055 13.0 1.1 2 7.9 0.0 2.4 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NOB1_Zn_bind PF08772.6 EGC30257.1 - 1.8e-26 91.7 1.0 1.8e-26 91.7 0.7 2.2 3 0 0 3 3 3 1 Nin one binding (NOB1) Zn-ribbon like Mitofilin PF09731.4 EGC30257.1 - 0.0021 16.8 10.1 0.0025 16.5 7.0 1.1 1 0 0 1 1 1 1 Mitochondrial inner membrane protein AF1Q PF15017.1 EGC30257.1 - 0.0041 17.0 2.3 0.0041 17.0 1.6 2.4 2 1 0 2 2 2 1 Drug resistance and apoptosis regulator DNA_RNApol_7kD PF03604.8 EGC30257.1 - 0.054 12.9 1.2 0.12 11.9 0.9 1.6 1 0 0 1 1 1 0 DNA directed RNA polymerase, 7 kDa subunit DUF4411 PF14367.1 EGC30257.1 - 0.092 12.4 9.2 0.59 9.8 1.8 3.4 3 1 1 4 4 4 0 Domain of unknown function (DUF4411) BH3 PF15285.1 EGC30257.1 - 0.17 11.4 0.0 0.33 10.5 0.0 1.4 1 0 0 1 1 1 0 Beclin-1 BH3 domain, Bcl-2-interacting GEMIN8 PF15348.1 EGC30257.1 - 0.27 11.2 11.8 0.44 10.5 8.2 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Tyrosinase PF00264.15 EGC30257.1 - 1 9.4 4.0 1.7 8.7 2.8 1.3 1 0 0 1 1 1 0 Common central domain of tyrosinase Ndc1_Nup PF09531.5 EGC30257.1 - 3.9 5.7 5.6 4.4 5.5 3.9 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup RIX1 PF08167.7 EGC30258.1 - 1.3e-09 37.9 3.3 1.3e-09 37.9 2.3 2.5 2 0 0 2 2 2 1 rRNA processing/ribosome biogenesis Prog_receptor PF02161.10 EGC30258.1 - 3.4 6.3 8.6 6.2 5.5 5.9 1.3 1 0 0 1 1 1 0 Progesterone receptor EF-hand_7 PF13499.1 EGC30259.1 - 3.9e-13 49.3 1.6 3.9e-13 49.3 1.1 3.0 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC30259.1 - 0.011 14.9 8.8 0.051 12.9 0.2 4.3 5 0 0 5 5 5 0 EF hand DUF418 PF04235.7 EGC30259.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF418) Peptidase_C14 PF00656.17 EGC30261.1 - 6.2e-08 32.6 0.0 5.8e-08 32.7 0.1 3.0 2 1 1 3 3 3 2 Caspase domain NRDE-2 PF08424.5 EGC30261.1 - 0.34 9.7 9.1 0.73 8.6 6.3 1.5 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Cbl_N2 PF02761.9 EGC30262.1 - 0.0056 16.7 0.0 0.017 15.1 0.0 1.8 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain PPTA PF01239.17 EGC30262.1 - 0.075 12.4 0.3 0.24 10.7 0.2 2.0 1 0 0 1 1 1 0 Protein prenyltransferase alpha subunit repeat NT-C2 PF10358.4 EGC30263.1 - 9.4e-23 80.2 7.9 2.2e-22 79.1 5.4 1.6 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins DIL PF01843.14 EGC30263.1 - 7.8e-20 70.7 1.8 2.7e-19 69.0 1.3 2.0 1 0 0 1 1 1 1 DIL domain WD40_alt PF14077.1 EGC30263.1 - 0.026 14.1 3.0 0.096 12.3 0.6 2.9 2 0 0 2 2 2 0 Alternative WD40 repeat motif Glutaredoxin2_C PF04399.8 EGC30263.1 - 0.3 10.6 0.0 0.3 10.6 0.0 3.4 3 0 0 3 3 3 0 Glutaredoxin 2, C terminal domain DUF1675 PF07897.6 EGC30263.1 - 4 7.2 12.0 0.92 9.3 5.8 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1675) DUF2935 PF11155.3 EGC30263.1 - 4.6 7.3 11.6 5.5 7.0 1.7 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF2935) Peptidase_C1 PF00112.18 EGC30264.1 - 1.7e-83 279.8 5.3 2.3e-83 279.3 3.7 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC30264.1 - 3.8e-12 46.2 0.5 7.6e-12 45.3 0.4 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC30264.1 - 0.0017 16.9 0.9 0.093 11.2 0.3 2.2 2 0 0 2 2 2 2 Peptidase C1-like family ABC_membrane_2 PF06472.10 EGC30265.1 - 2.1e-100 335.5 0.9 2.8e-100 335.0 0.6 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGC30265.1 - 1.3e-17 64.4 0.0 3.7e-17 62.8 0.0 1.8 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGC30265.1 - 0.0002 20.6 0.0 0.034 13.3 0.0 2.6 2 0 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGC30265.1 - 0.00029 21.2 0.3 0.0034 17.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGC30265.1 - 0.00044 19.7 0.0 0.001 18.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGC30265.1 - 0.00064 19.7 0.0 0.0023 17.9 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC30265.1 - 0.0033 18.2 0.0 0.01 16.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain SbmA_BacA PF05992.7 EGC30265.1 - 0.0042 16.3 0.0 0.01 15.0 0.0 1.5 1 1 0 1 1 1 1 SbmA/BacA-like family ABC_membrane PF00664.18 EGC30265.1 - 0.0042 16.5 0.0 0.0075 15.7 0.0 1.4 1 0 0 1 1 1 1 ABC transporter transmembrane region DUF815 PF05673.8 EGC30265.1 - 0.027 13.4 0.1 0.12 11.2 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EGC30265.1 - 0.071 13.4 0.0 0.51 10.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF4366 PF14283.1 EGC30265.1 - 0.081 12.3 0.1 0.13 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) AAA_16 PF13191.1 EGC30265.1 - 0.093 12.7 0.0 0.18 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EGC30265.1 - 0.12 11.7 0.0 0.47 9.8 0.0 2.0 2 0 0 2 2 2 0 AAA-like domain T2SE PF00437.15 EGC30265.1 - 0.14 11.0 0.0 0.24 10.2 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Metallophos PF00149.23 EGC30266.1 - 4.7e-17 62.0 1.6 4.7e-17 62.0 1.1 1.9 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC30266.1 - 0.04 13.7 0.1 0.32 10.8 0.1 2.2 1 1 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain SapB_1 PF05184.10 EGC30266.1 - 0.072 12.9 0.3 0.072 12.9 0.2 2.1 2 0 0 2 2 2 0 Saposin-like type B, region 1 GRAM PF02893.15 EGC30267.1 - 2.5e-28 97.3 12.9 7e-17 60.7 0.2 4.7 5 0 0 5 5 5 3 GRAM domain Glyco_transf_28 PF03033.15 EGC30267.1 - 8.1e-23 80.7 0.0 1.5e-22 79.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain FYVE PF01363.16 EGC30267.1 - 1.6e-13 50.3 9.1 3.2e-13 49.3 6.3 1.4 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGC30267.1 - 1.9e-11 44.0 1.0 1.9e-11 44.0 0.7 3.6 4 0 0 4 4 4 1 PH domain UDPGT PF00201.13 EGC30267.1 - 3.6e-06 25.8 0.0 8e-06 24.6 0.0 1.5 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase Glyco_tran_28_C PF04101.11 EGC30267.1 - 5.9e-05 22.7 0.0 0.00025 20.7 0.0 2.1 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain FYVE_2 PF02318.11 EGC30267.1 - 0.0051 16.7 7.6 0.013 15.3 5.3 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger Vps36_ESCRT-II PF11605.3 EGC30267.1 - 0.0061 16.3 1.6 13 5.6 0.0 4.4 4 0 0 4 4 4 1 Vacuolar protein sorting protein 36 Vps36 zf-B_box PF00643.19 EGC30267.1 - 0.33 10.8 7.9 1 9.3 5.5 1.8 1 0 0 1 1 1 0 B-box zinc finger PBP1_TM PF14812.1 EGC30267.1 - 4.9 7.5 7.6 7.1 7.0 0.1 2.5 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SMC_Nse1 PF07574.8 EGC30268.1 - 8.9e-15 54.8 4.5 8.3e-11 41.8 1.3 3.0 2 1 1 3 3 3 2 Nse1 non-SMC component of SMC5-6 complex zf-RING_2 PF13639.1 EGC30268.1 - 0.00014 21.5 8.8 0.00022 20.9 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING-like PF08746.6 EGC30268.1 - 0.00029 20.7 9.0 0.00057 19.8 6.2 1.5 1 0 0 1 1 1 1 RING-like domain zf-HC5HC2H PF13771.1 EGC30268.1 - 0.0026 17.8 1.8 0.0064 16.6 1.3 1.7 1 0 0 1 1 1 1 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EGC30268.1 - 0.0037 17.2 1.3 0.0037 17.2 0.9 1.8 2 0 0 2 2 2 1 PHD-zinc-finger like domain DUF257 PF03192.8 EGC30268.1 - 0.042 13.1 0.7 0.064 12.5 0.5 1.2 1 0 0 1 1 1 0 Pyrococcus protein of unknown function, DUF257 FANCL_C PF11793.3 EGC30268.1 - 0.086 12.8 9.8 0.62 10.0 6.8 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain PHD PF00628.24 EGC30268.1 - 0.15 11.7 9.3 0.26 11.0 6.5 1.4 1 0 0 1 1 1 0 PHD-finger zf-RING_4 PF14570.1 EGC30268.1 - 0.16 11.6 8.5 0.32 10.6 5.9 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EGC30268.1 - 0.2 11.7 8.3 1.2 9.1 5.8 2.1 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGC30268.1 - 1.5 8.8 7.3 3.4 7.7 5.1 1.6 1 1 0 1 1 1 0 RING-variant domain zf-C3HC4_3 PF13920.1 EGC30268.1 - 2.6 7.8 7.8 5 6.8 5.4 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC30268.1 - 4.4 7.0 10.9 19 4.9 7.6 2.0 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Ras PF00071.17 EGC30270.1 - 2.1e-08 33.7 0.8 3.2e-08 33.1 0.5 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30270.1 - 5.2e-06 26.9 0.5 1.1e-05 25.9 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein DUF99 PF01949.11 EGC30270.1 - 0.0036 16.4 0.1 0.0054 15.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function DUF99 SusE PF14292.1 EGC30270.1 - 0.011 15.5 0.1 0.025 14.4 0.1 1.6 1 1 0 1 1 1 0 SusE outer membrane protein GATase_5 PF13507.1 EGC30271.1 - 9.9e-97 322.8 0.1 1.5e-96 322.2 0.0 1.3 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain AIRS_C PF02769.17 EGC30271.1 - 8e-35 120.1 0.7 1.2e-17 64.3 0.0 2.3 2 0 0 2 2 2 2 AIR synthase related protein, C-terminal domain AIRS PF00586.19 EGC30271.1 - 8.6e-16 57.9 0.0 3.9e-15 55.8 0.0 2.2 2 0 0 2 2 2 1 AIR synthase related protein, N-terminal domain Glycoprotein PF03409.10 EGC30272.1 - 0.051 12.3 0.1 0.076 11.7 0.1 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Cag12 PF13117.1 EGC30272.1 - 0.18 11.7 1.3 0.26 11.2 0.1 2.0 2 1 0 2 2 2 0 Cag pathogenicity island protein Cag12 RRM_1 PF00076.17 EGC30273.1 - 2.2e-27 94.4 2.5 6.6e-13 48.0 0.0 3.7 4 1 0 4 4 4 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC30273.1 - 1.2e-16 60.2 0.3 2e-11 43.5 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC30273.1 - 1.4e-14 53.8 0.6 8.6e-06 25.6 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF2573 PF10835.3 EGC30273.1 - 0.021 14.8 0.6 0.039 13.9 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) DUF4523 PF15023.1 EGC30273.1 - 0.047 13.2 0.0 0.13 11.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF4523) DSPc PF00782.15 EGC30274.1 - 4.1e-27 94.3 0.0 4.1e-27 94.3 0.0 3.2 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.17 EGC30274.1 - 0.00035 20.1 0.1 0.00088 18.9 0.1 1.6 1 0 0 1 1 1 1 Gelsolin repeat CDKN3 PF05706.7 EGC30274.1 - 0.0028 17.1 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) PTPlike_phytase PF14566.1 EGC30274.1 - 0.23 11.5 0.0 0.23 11.5 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate zf-B_box PF00643.19 EGC30275.1 - 0.00034 20.4 9.7 0.00086 19.1 6.7 1.7 1 0 0 1 1 1 1 B-box zinc finger SEC-C PF02810.10 EGC30275.1 - 0.014 14.8 0.3 0.014 14.8 0.2 1.8 2 0 0 2 2 2 0 SEC-C motif Herpes_LMP1 PF05297.6 EGC30275.1 - 0.33 9.8 2.6 0.41 9.5 1.8 1.1 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) DUF3277 PF11681.3 EGC30276.1 - 0.087 12.3 0.3 0.12 11.8 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3277) Dynactin PF12455.3 EGC30277.1 - 0.025 13.5 0.0 0.025 13.5 0.0 1.1 1 0 0 1 1 1 0 Dynein associated protein SR-25 PF10500.4 EGC30277.1 - 0.35 10.3 3.2 0.36 10.2 2.2 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein WD40 PF00400.27 EGC30281.1 - 3.3e-29 99.6 24.9 8.7e-09 34.9 0.0 6.7 6 0 0 6 6 6 6 WD domain, G-beta repeat bZIP_1 PF00170.16 EGC30281.1 - 0.083 12.8 1.7 0.19 11.7 1.2 1.5 1 0 0 1 1 1 0 bZIP transcription factor TFIIA PF03153.8 EGC30281.1 - 1.6 8.5 31.7 0.31 10.8 9.2 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 EGC30281.1 - 7.6 5.4 21.7 0.04 12.9 8.6 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter PIG-F PF06699.6 EGC30282.1 - 1.2e-40 139.5 9.4 2.8e-40 138.2 6.5 1.6 1 1 0 1 1 1 1 GPI biosynthesis protein family Pig-F Pribosyltran_N PF13793.1 EGC30283.1 - 3e-47 159.1 0.7 2.3e-45 153.0 0.0 2.3 2 1 0 2 2 2 2 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGC30283.1 - 2.1e-43 148.1 5.7 5.7e-39 133.7 0.9 3.3 3 1 1 4 4 4 2 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGC30283.1 - 9e-13 48.0 1.2 2.5e-12 46.5 0.8 1.8 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGC30283.1 - 0.0029 16.8 0.2 0.0055 15.9 0.2 1.4 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase DUF4461 PF14688.1 EGC30284.1 - 1.1e-34 120.2 2.8 1.3e-32 113.4 0.3 2.2 2 0 0 2 2 2 2 Domain of unknown function (DUF4461) DUF4460 PF14687.1 EGC30284.1 - 1.8e-28 98.5 4.9 1.8e-28 98.5 3.4 4.1 4 0 0 4 4 4 1 Domain of unknown function (DUF4460) SNURF PF07192.6 EGC30284.1 - 0.016 15.0 0.0 0.049 13.4 0.0 1.8 1 0 0 1 1 1 0 SNURF/RPN4 protein RNB PF00773.14 EGC30285.1 - 7e-59 199.7 7.3 7e-59 199.7 5.1 5.4 4 2 0 4 4 4 1 RNB domain RRM_1 PF00076.17 EGC30286.1 - 7.6e-73 240.1 8.8 8.5e-18 63.7 0.0 5.5 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC30286.1 - 2.3e-64 213.2 1.1 1.9e-17 63.0 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC30286.1 - 3.7e-40 135.5 0.1 2e-10 40.3 0.0 5.4 5 0 0 5 5 5 5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC30286.1 - 8.5e-05 22.2 0.0 1.2 8.9 0.0 3.8 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif RRM_2 PF04059.7 EGC30286.1 - 0.04 13.9 2.1 1.1 9.2 0.0 3.5 4 0 0 4 4 4 0 RNA recognition motif 2 Mrr_cat PF04471.7 EGC30287.1 - 1.5e-08 34.4 0.0 3.3e-08 33.3 0.0 1.6 1 1 0 1 1 1 1 Restriction endonuclease DUF4090 PF13319.1 EGC30287.1 - 0.0026 17.6 0.0 0.0056 16.5 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF4090) NERD PF08378.6 EGC30287.1 - 0.12 12.6 0.0 0.23 11.7 0.0 1.6 1 1 0 1 1 1 0 Nuclease-related domain KLRAQ PF10205.4 EGC30288.1 - 6e-15 55.1 9.5 6e-15 55.1 6.6 6.0 5 1 1 6 6 6 2 Predicted coiled-coil domain-containing protein TTKRSYEDQ PF10212.4 EGC30288.1 - 5.1e-11 42.1 4.6 5.1e-11 42.1 3.2 3.7 4 1 0 4 4 4 1 Predicted coiled-coil domain-containing protein DUF1515 PF07439.6 EGC30288.1 - 0.0039 16.9 0.2 0.0039 16.9 0.1 4.4 4 2 2 7 7 7 1 Protein of unknown function (DUF1515) DUF641 PF04859.7 EGC30288.1 - 0.0097 15.6 3.0 0.0097 15.6 2.1 7.0 4 2 2 7 7 7 2 Plant protein of unknown function (DUF641) TatD_DNase PF01026.16 EGC30289.1 - 8.4e-38 130.0 0.0 1e-37 129.7 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase CN_hydrolase PF00795.17 EGC30290.1 - 0.13 11.5 0.0 0.17 11.1 0.0 1.3 1 0 0 1 1 1 0 Carbon-nitrogen hydrolase UbiA PF01040.13 EGC30291.1 - 1e-17 64.2 11.4 1.3e-17 63.9 7.9 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family Ten1 PF12658.2 EGC30291.1 - 0.082 12.6 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Telomere capping, CST complex subunit Adaptin_N PF01602.15 EGC30292.1 - 4.1e-88 295.9 8.7 1.8e-87 293.8 6.0 1.8 1 1 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGC30292.1 - 8.6e-07 28.9 7.6 1.3e-05 25.1 0.1 4.1 3 1 1 4 4 4 1 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 EGC30292.1 - 1.2e-06 28.3 0.0 1.2e-06 28.3 0.0 2.5 2 1 0 2 2 2 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 EGC30292.1 - 0.00047 20.3 0.0 0.026 14.8 0.0 3.4 1 1 2 3 3 3 1 HEAT repeats HEAT PF02985.17 EGC30292.1 - 0.021 14.8 0.0 9.9 6.5 0.0 4.3 4 0 0 4 4 4 0 HEAT repeat DUF3417 PF11897.3 EGC30292.1 - 0.023 14.6 0.0 0.063 13.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) adh_short PF00106.20 EGC30293.1 - 2.7e-33 115.2 0.5 3.2e-33 114.9 0.3 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC30293.1 - 3e-30 105.7 0.4 3.6e-30 105.5 0.3 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC30293.1 - 1.2e-15 57.6 0.5 1.5e-15 57.3 0.3 1.1 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC30293.1 - 6.3e-07 29.0 1.2 9.5e-06 25.2 0.9 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC30293.1 - 5.6e-05 21.9 2.8 8.2e-05 21.4 1.6 1.5 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGC30293.1 - 0.0052 16.8 0.7 0.008 16.1 0.5 1.5 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_2 PF03446.10 EGC30293.1 - 0.0079 16.0 0.3 0.014 15.2 0.2 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase 3HCDH_N PF02737.13 EGC30293.1 - 0.011 15.4 1.4 0.017 14.7 1.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain THF_DHG_CYH_C PF02882.14 EGC30293.1 - 0.028 13.4 0.9 0.056 12.5 0.6 1.6 1 0 0 1 1 1 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Eno-Rase_NADH_b PF12242.3 EGC30293.1 - 0.058 13.1 0.1 0.17 11.6 0.0 1.9 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase 2-Hacid_dh_C PF02826.14 EGC30293.1 - 0.11 11.6 0.2 0.17 11.0 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain GvpH PF05455.6 EGC30295.1 - 0.00039 20.0 0.7 0.034 13.7 0.0 2.5 2 0 0 2 2 2 2 GvpH Toxin_39 PF15500.1 EGC30296.1 - 0.14 12.3 0.7 9.8 6.3 0.0 2.1 1 1 1 2 2 2 0 Putative RNase-like toxin Sterile PF03015.14 EGC30296.1 - 0.18 12.1 0.6 0.43 10.8 0.0 1.8 2 0 0 2 2 2 0 Male sterility protein DUF2951 PF11166.3 EGC30296.1 - 0.34 10.7 5.5 0.45 10.3 3.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) zf-RING_2 PF13639.1 EGC30299.1 - 1.9e-08 33.9 11.8 1.9e-08 33.9 8.2 2.1 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC30299.1 - 5.3e-07 29.1 9.0 1.3e-06 27.9 6.2 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC30299.1 - 5.7e-06 25.8 13.8 5.7e-06 25.8 9.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30299.1 - 4.1e-05 23.5 8.2 0.00014 21.9 5.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC30299.1 - 0.00011 22.1 13.8 0.00011 22.1 9.6 2.2 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30299.1 - 0.00077 19.1 10.7 0.00077 19.1 7.4 2.0 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC30299.1 - 0.0069 15.9 12.8 0.017 14.7 8.9 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGC30299.1 - 0.0082 16.0 10.4 0.0082 16.0 7.2 2.3 2 1 0 2 2 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC30299.1 - 0.0084 15.9 2.7 0.018 14.9 1.8 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGC30299.1 - 0.061 13.1 4.2 0.14 11.9 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC30299.1 - 1.7 8.4 11.3 2 8.2 4.9 3.4 3 0 0 3 3 3 0 RING-type zinc-finger T4_baseplate PF12322.3 EGC30300.1 - 0.07 12.3 0.1 0.084 12.1 0.1 1.3 1 1 0 1 1 1 0 T4 bacteriophage base plate protein SecB PF02556.9 EGC30302.1 - 0.022 14.3 0.1 0.052 13.1 0.1 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit SecB DUF3979 PF13141.1 EGC30302.1 - 0.089 12.6 1.6 0.27 11.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3979) Lbh PF15317.1 EGC30303.1 - 0.019 15.2 1.4 0.019 15.2 1.0 1.8 2 0 0 2 2 2 0 Cardiac transcription factor regulator, Developmental protein PDZ_1 PF12812.2 EGC30303.1 - 0.029 14.2 0.2 0.063 13.1 0.1 1.7 1 1 1 2 2 2 0 PDZ-like domain BPL_N PF09825.4 EGC30303.1 - 0.95 8.1 4.2 0.92 8.2 2.9 1.2 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal AhpC-TSA_2 PF13911.1 EGC30304.1 - 1.5e-21 76.4 0.0 8.7e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA antioxidant enzyme AhpC-TSA PF00578.16 EGC30304.1 - 2.5e-06 27.1 0.0 7.7e-06 25.6 0.0 1.8 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC30304.1 - 0.00046 19.7 0.0 0.0012 18.4 0.0 1.6 1 0 0 1 1 1 1 Redoxin Arf PF00025.16 EGC30305.1 - 3e-47 160.1 0.0 3.7e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC30305.1 - 2.5e-15 56.2 0.0 3e-15 55.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC30305.1 - 9.6e-13 47.7 0.1 1.2e-12 47.4 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC30305.1 - 1.4e-12 47.2 0.1 1.7e-12 46.9 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC30305.1 - 3.9e-11 42.9 0.0 7e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC30305.1 - 5e-11 43.1 0.0 1.1e-10 41.9 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein G-alpha PF00503.15 EGC30305.1 - 1.9e-10 40.0 5.4 2.6e-09 36.2 2.0 2.8 1 1 1 2 2 2 1 G-protein alpha subunit GTP_EFTU PF00009.22 EGC30305.1 - 9.4e-07 28.4 0.1 2e-05 24.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGC30305.1 - 0.0077 15.5 0.9 0.025 13.8 0.6 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B cobW PF02492.14 EGC30305.1 - 0.0092 15.4 0.7 1.2 8.5 0.1 2.2 1 1 1 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EGC30305.1 - 0.021 14.2 0.0 0.28 10.6 0.0 2.4 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGC30305.1 - 0.036 13.9 0.4 0.17 11.7 0.3 2.3 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGC30305.1 - 0.047 13.3 0.0 1.5 8.5 0.0 2.2 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGC30305.1 - 0.067 12.8 0.8 0.23 11.1 0.6 1.8 1 1 0 1 1 1 0 NACHT domain Ret_tiss PF10044.4 EGC30306.1 - 0.033 14.7 1.1 0.17 12.4 0.1 2.6 2 0 0 2 2 2 0 Retinal tissue protein Ribosomal_L36e PF01158.13 EGC30307.1 - 1.4e-30 105.1 5.8 1.5e-30 105.0 4.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L36e DKCLD PF08068.7 EGC30307.1 - 0.023 14.5 0.0 0.046 13.6 0.0 1.7 1 1 0 1 1 1 0 DKCLD (NUC011) domain CDP-OH_P_transf PF01066.16 EGC30308.1 - 6e-18 65.0 6.5 6e-18 65.0 4.5 2.8 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase Syja_N PF02383.13 EGC30309.1 - 2e-94 315.9 5.5 4.7e-94 314.7 2.0 2.0 2 0 0 2 2 2 1 SacI homology domain DUF3098 PF11297.3 EGC30309.1 - 0.07 12.8 0.2 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3098) PA14 PF07691.7 EGC30310.1 - 5.8e-06 26.0 0.0 1e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 PA14 domain Thioredoxin PF00085.15 EGC30311.1 - 1.6e-15 56.6 0.0 2.9e-15 55.8 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin AAA_23 PF13476.1 EGC30311.1 - 0.017 15.4 5.7 0.02 15.2 3.9 1.2 1 0 0 1 1 1 0 AAA domain Thioredoxin_8 PF13905.1 EGC30311.1 - 0.063 13.4 0.4 0.49 10.5 0.1 2.4 1 1 1 2 2 2 0 Thioredoxin-like DUF2909 PF11137.3 EGC30311.1 - 0.079 12.7 0.2 0.19 11.4 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2909) Thioredoxin_2 PF13098.1 EGC30311.1 - 0.15 12.3 3.8 0.19 11.9 0.2 2.6 2 1 0 2 2 2 0 Thioredoxin-like domain DUF3245 PF11595.3 EGC30311.1 - 0.4 10.9 5.6 0.67 10.2 3.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3245) OmpH PF03938.9 EGC30311.1 - 0.47 10.3 8.6 0.73 9.7 6.0 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Thioredoxin_4 PF13462.1 EGC30311.1 - 0.59 10.1 3.6 2.5 8.1 2.5 1.9 1 1 0 1 1 1 0 Thioredoxin DUF4349 PF14257.1 EGC30311.1 - 3.7 6.6 5.7 6.5 5.8 3.9 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4349) TMPIT PF07851.8 EGC30311.1 - 4 6.4 6.8 6.4 5.7 4.5 1.5 1 1 0 1 1 1 0 TMPIT-like protein Thiolase_N PF00108.18 EGC30312.1 - 3.7e-97 324.4 0.4 5.5e-97 323.8 0.2 1.2 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGC30312.1 - 3.8e-46 155.5 1.0 2.2e-45 153.0 0.4 2.2 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGC30312.1 - 6.8e-07 29.0 1.1 2.4e-05 23.9 0.3 2.7 2 1 1 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain Kelch_1 PF01344.20 EGC30313.1 - 1.7e-42 142.6 16.1 1e-07 31.3 0.3 7.1 7 0 0 7 7 7 6 Kelch motif Kelch_6 PF13964.1 EGC30313.1 - 8.7e-42 139.6 7.2 2.4e-07 30.6 0.0 7.1 2 1 5 7 7 7 6 Kelch motif Kelch_4 PF13418.1 EGC30313.1 - 2.4e-28 97.6 1.2 2.7e-05 23.8 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC30313.1 - 5.6e-18 64.5 0.0 0.011 15.8 0.0 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC30313.1 - 3.2e-14 52.4 15.1 0.0067 16.3 0.0 7.2 7 0 0 7 7 7 5 Kelch motif Kelch_2 PF07646.10 EGC30313.1 - 1.2e-10 40.6 7.8 0.0013 18.3 0.0 6.0 5 1 1 6 6 6 2 Kelch motif zf-B_box PF00643.19 EGC30313.1 - 4.5e-07 29.6 4.5 4.5e-07 29.6 3.1 3.0 3 0 0 3 3 2 1 B-box zinc finger zf-C3HC4_4 PF15227.1 EGC30313.1 - 0.00012 21.8 13.4 0.00012 21.8 9.3 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC30313.1 - 0.0027 17.3 7.5 0.013 15.1 5.2 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4 PF00097.20 EGC30313.1 - 0.0031 17.1 14.8 0.0031 17.1 10.3 2.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30313.1 - 0.042 13.5 24.7 0.62 9.8 9.2 2.5 2 0 0 2 2 2 0 zinc-RING finger domain RB_B PF01857.15 EGC30313.1 - 0.22 11.0 5.4 0.14 11.6 2.2 2.0 2 0 0 2 2 2 0 Retinoblastoma-associated protein B domain zf-C3HC4_2 PF13923.1 EGC30313.1 - 5.8 7.0 26.6 0.09 12.8 10.0 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC30313.1 - 8.5 6.2 23.0 0.021 14.6 7.4 2.4 2 0 0 2 2 2 0 Ring finger domain CKS PF01111.14 EGC30314.1 - 2.2e-31 107.4 0.1 2.7e-31 107.2 0.1 1.0 1 0 0 1 1 1 1 Cyclin-dependent kinase regulatory subunit UPF0113 PF03657.8 EGC30315.1 - 1.6e-06 27.8 0.0 2e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0113) PUA PF01472.15 EGC30315.1 - 0.014 15.0 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 PUA domain Nol1_Nop2_Fmu_2 PF13636.1 EGC30315.1 - 0.072 13.1 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 pre-rRNA processing and ribosome biogenesis CLN5 PF15014.1 EGC30316.1 - 1.2e-14 54.4 5.5 1.6e-14 53.9 3.8 1.2 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 ATG27 PF09451.5 EGC30316.1 - 2.9e-07 30.0 0.1 5.7e-07 29.0 0.1 1.4 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EGC30316.1 - 1.3e-05 24.3 0.0 3.1e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Med21 PF11221.3 EGC30317.1 - 7.5 6.5 9.2 0.086 12.8 0.8 2.0 2 0 0 2 2 2 0 Subunit 21 of Mediator complex Abhydrolase_5 PF12695.2 EGC30318.1 - 2.9e-08 33.5 0.0 3.6e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC30318.1 - 0.016 15.0 0.0 4.1 7.2 0.0 2.1 2 0 0 2 2 2 0 Alpha/beta hydrolase family Trp_Tyr_perm PF03222.8 EGC30319.1 - 2.4e-06 26.6 1.3 2.4e-06 26.6 0.9 2.8 3 1 0 3 3 3 1 Tryptophan/tyrosine permease family Dicty_REP PF05086.7 EGC30321.1 - 5.6e-188 626.7 70.1 6.3e-188 626.5 48.6 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Glyco_hydro_98C PF08307.6 EGC30322.1 - 0.089 12.0 0.1 0.092 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Glyco_hydro_98C PF08307.6 EGC30323.1 - 0.089 12.0 0.1 0.092 12.0 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 98 C-terminal domain Methyltransf_11 PF08241.7 EGC30324.1 - 3.4e-18 65.9 0.0 5.9e-18 65.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC30324.1 - 2.5e-12 46.6 0.0 3.3e-12 46.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC30324.1 - 2.1e-10 40.5 0.0 3e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30324.1 - 4e-09 37.0 0.0 7e-09 36.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC30324.1 - 5.3e-09 36.3 0.0 9.7e-09 35.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC30324.1 - 3e-08 34.0 0.0 5.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC30324.1 - 3.2e-06 26.4 0.0 6.7e-06 25.3 0.0 1.5 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_8 PF05148.10 EGC30324.1 - 4.1e-06 26.5 0.0 6.5e-06 25.9 0.0 1.3 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EGC30324.1 - 0.00025 19.5 0.0 0.00033 19.1 0.0 1.1 1 0 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase TehB PF03848.9 EGC30324.1 - 0.00059 19.0 0.0 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_15 PF09445.5 EGC30324.1 - 0.00099 18.6 0.0 0.002 17.7 0.0 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGC30324.1 - 0.0088 15.4 0.1 0.025 13.9 0.0 1.8 2 1 0 2 2 2 1 Methyltransferase small domain PrmA PF06325.8 EGC30324.1 - 0.019 14.1 0.0 0.027 13.6 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_2 PF00891.13 EGC30324.1 - 0.036 13.2 0.0 0.06 12.5 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase GidB PF02527.10 EGC30324.1 - 0.049 12.7 0.0 0.17 10.9 0.0 1.8 1 1 0 1 1 1 0 rRNA small subunit methyltransferase G Methyltransf_4 PF02390.12 EGC30324.1 - 0.059 12.4 0.0 0.13 11.2 0.0 1.7 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_26 PF13659.1 EGC30324.1 - 0.15 12.0 0.0 0.48 10.4 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Pentapeptide PF00805.17 EGC30325.1 - 3e-22 77.3 16.0 7.3e-11 41.0 1.2 4.4 2 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGC30325.1 - 7.7e-22 76.9 32.6 4.2e-11 42.5 9.8 3.6 1 1 2 3 3 3 3 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EGC30325.1 - 9.7e-18 64.1 0.0 2.8e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 EGC30325.1 - 2.8e-17 62.3 35.5 3.3e-08 33.2 0.7 4.8 1 1 3 4 4 4 4 Pentapeptide repeats (9 copies) BTB PF00651.26 EGC30325.1 - 0.0013 18.6 0.0 0.0033 17.3 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain Pex26 PF07163.7 EGC30325.1 - 7.4 5.3 6.4 11 4.7 4.4 1.2 1 0 0 1 1 1 0 Pex26 protein Glyco_hydro_31 PF01055.21 EGC30327.1 - 2.6e-158 527.5 3.0 3.2e-158 527.1 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGC30327.1 - 3.2e-09 36.5 4.5 3.7e-09 36.3 0.3 2.9 3 0 0 3 3 3 1 Galactose mutarotase-like Prenyltrans PF00432.16 EGC30328.1 - 2.1e-36 123.1 8.7 9e-14 50.7 0.1 5.7 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGC30328.1 - 3.9e-24 85.2 0.5 6e-16 58.8 0.0 3.6 1 1 2 3 3 3 2 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGC30328.1 - 1.4e-06 28.2 0.0 0.081 12.9 0.0 3.6 1 1 2 3 3 3 3 Prenyltransferase-like EamA PF00892.15 EGC30329.1 - 1.2e-09 38.2 28.2 1.1e-06 28.7 6.4 2.5 2 1 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGC30329.1 - 0.00048 20.3 3.6 0.00048 20.3 2.5 2.6 2 1 0 2 2 2 1 Multidrug resistance efflux transporter UAA PF08449.6 EGC30329.1 - 0.0014 17.6 20.0 0.0044 15.9 13.9 2.0 1 1 0 1 1 1 1 UAA transporter family CcmD PF04995.9 EGC30329.1 - 0.039 13.6 0.0 0.13 11.9 0.0 2.0 1 0 0 1 1 1 0 Heme exporter protein D (CcmD) zf-TRAF PF02176.13 EGC30330.1 - 2.1e-13 50.4 30.4 1.6e-08 34.7 6.7 5.0 3 1 2 5 5 5 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC30330.1 - 3.4e-05 23.7 11.2 3.4e-05 23.7 7.7 3.7 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC30330.1 - 0.0015 18.3 9.5 0.0015 18.3 6.6 3.0 2 1 0 2 2 2 1 Ring finger domain zf-RING_4 PF14570.1 EGC30330.1 - 0.0021 17.5 10.1 0.0021 17.5 7.0 4.1 2 1 2 4 4 4 1 RING/Ubox like zinc-binding domain DUF3791 PF12668.2 EGC30330.1 - 0.0056 16.2 2.6 0.013 15.1 0.4 2.7 2 1 0 2 2 2 1 Protein of unknown function (DUF3791) Tropomyosin_1 PF12718.2 EGC30330.1 - 0.0088 15.8 1.3 0.0088 15.8 0.9 2.0 2 0 0 2 2 2 1 Tropomyosin like zf-C2HC_2 PF13913.1 EGC30330.1 - 0.04 13.5 0.2 0.04 13.5 0.1 3.4 3 0 0 3 3 3 0 zinc-finger of a C2HC-type Sina PF03145.11 EGC30330.1 - 0.8 9.3 28.8 0.087 12.4 0.4 4.3 2 1 3 5 5 5 0 Seven in absentia protein family UQ_con PF00179.21 EGC30331.1 - 5.2e-33 113.4 0.0 6e-33 113.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC30331.1 - 1.6e-05 24.6 0.0 2.1e-05 24.2 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC30331.1 - 0.004 17.0 0.0 0.0051 16.7 0.0 1.3 1 0 0 1 1 1 1 RWD domain UFC1 PF08694.6 EGC30331.1 - 0.04 13.4 0.0 0.15 11.5 0.0 1.8 1 1 1 2 2 2 0 Ubiquitin-fold modifier-conjugating enzyme 1 Rotamase PF00639.16 EGC30332.1 - 1.5e-26 92.9 0.0 2.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain Rotamase_3 PF13616.1 EGC30332.1 - 2.4e-22 79.3 0.0 3.7e-22 78.7 0.0 1.3 1 0 0 1 1 1 1 PPIC-type PPIASE domain FHA PF00498.21 EGC30332.1 - 1.1e-17 63.8 0.0 2.8e-17 62.5 0.0 1.7 1 0 0 1 1 1 1 FHA domain Rotamase_2 PF13145.1 EGC30332.1 - 7.2e-05 23.4 0.0 0.00028 21.5 0.0 2.0 3 0 0 3 3 3 1 PPIC-type PPIASE domain Pkinase PF00069.20 EGC30333.1 - 3.3e-80 268.9 0.0 3.9e-80 268.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30333.1 - 1.9e-38 132.0 0.0 2.3e-38 131.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC30333.1 - 1.9e-06 27.0 0.0 2.6e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC30333.1 - 1.2e-05 24.4 0.0 5.1e-05 22.3 0.0 1.8 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGC30333.1 - 0.0023 17.6 0.0 0.012 15.3 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGC30333.1 - 0.0027 17.0 0.1 0.0046 16.3 0.1 1.5 1 1 0 1 1 1 1 PhoP regulatory network protein YrbL RIO1 PF01163.17 EGC30333.1 - 0.0098 15.2 0.9 0.031 13.6 0.6 1.8 1 1 0 1 1 1 1 RIO1 family Antimicrobial_8 PF08103.6 EGC30333.1 - 0.012 15.4 0.4 0.07 13.0 0.1 2.3 2 0 0 2 2 2 0 Uperin family Pox_ser-thr_kin PF05445.6 EGC30333.1 - 0.012 14.3 0.1 0.022 13.5 0.1 1.3 1 0 0 1 1 1 0 Poxvirus serine/threonine protein kinase RasGEF PF00617.14 EGC30334.1 - 2.9e-63 212.9 1.0 2.9e-63 212.9 0.7 2.4 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC30334.1 - 2.4e-27 95.0 0.9 2.4e-27 95.0 0.6 6.0 6 1 0 6 6 6 1 RasGEF N-terminal motif HisG_C PF08029.6 EGC30335.1 - 0.041 13.8 0.0 0.06 13.2 0.0 1.3 1 0 0 1 1 1 0 HisG, C-terminal domain CutA1 PF03091.10 EGC30335.1 - 0.089 12.4 0.1 0.14 11.8 0.1 1.2 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein AP_endonuc_2 PF01261.19 EGC30336.1 - 3.9e-30 104.7 0.0 5.3e-30 104.2 0.0 1.2 1 0 0 1 1 1 1 Xylose isomerase-like TIM barrel DUF1731 PF08338.6 EGC30338.1 - 1.2e-15 56.6 0.0 2.1e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF1731) Epimerase PF01370.16 EGC30338.1 - 2.1e-14 53.5 0.0 8.9e-12 44.9 0.0 2.4 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGC30338.1 - 2.9e-05 23.0 0.0 7e-05 21.8 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_4 PF07993.7 EGC30338.1 - 0.0027 16.6 0.0 0.07 12.0 0.0 2.3 1 1 1 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EGC30338.1 - 0.013 15.8 0.0 0.026 14.8 0.0 1.6 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGC30338.1 - 0.014 15.3 0.0 0.026 14.4 0.0 1.5 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus 3Beta_HSD PF01073.14 EGC30338.1 - 0.042 12.5 0.0 0.083 11.5 0.0 1.6 1 1 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family ETRAMP PF09716.5 EGC30338.1 - 0.95 9.4 3.9 1.9 8.4 1.6 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FNIP PF05725.7 EGC30339.1 - 2.7e-38 129.6 49.8 4.4e-06 26.5 0.3 9.6 2 2 8 11 11 11 11 FNIP Repeat DUF835 PF05763.7 EGC30339.1 - 0.37 10.3 1.9 70 2.9 0.0 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF835) HAD_2 PF13419.1 EGC30341.1 - 0.1 12.7 0.2 0.49 10.5 0.0 2.2 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase HVSL PF09749.4 EGC30344.1 - 4.3e-42 143.7 2.3 6.7e-42 143.1 1.6 1.3 1 0 0 1 1 1 1 Uncharacterised conserved protein RNA_pol_Rpc4 PF05132.9 EGC30344.1 - 5.4 7.0 9.3 1.8 8.5 3.1 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 CBM49 PF09478.5 EGC30345.1 - 1.5e-10 40.9 0.7 2e-10 40.6 0.5 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RabGAP-TBC PF00566.13 EGC30346.1 - 3.3e-41 141.1 10.1 3.3e-41 141.1 7.0 2.2 2 1 0 2 2 2 1 Rab-GTPase-TBC domain Cyclin_N PF00134.18 EGC30347.1 - 3.6e-15 55.6 1.0 3.6e-15 55.6 0.7 1.8 2 1 0 2 2 2 1 Cyclin, N-terminal domain TFIIB PF00382.14 EGC30347.1 - 0.00015 21.5 0.0 0.00032 20.4 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIIB repeat Pro_isomerase PF00160.16 EGC30348.1 - 4.8e-49 166.5 1.3 1.4e-48 165.0 0.4 2.0 2 0 0 2 2 2 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD WD40 PF00400.27 EGC30348.1 - 6e-10 38.6 1.4 1.4e-07 31.1 0.1 3.8 4 0 0 4 4 4 1 WD domain, G-beta repeat Ten_N PF06484.7 EGC30348.1 - 0.049 12.7 0.1 0.087 11.9 0.1 1.3 1 0 0 1 1 1 0 Teneurin Intracellular Region DUF3592 PF12158.3 EGC30349.1 - 0.024 14.4 0.7 0.024 14.4 0.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3592) DUF3923 PF13061.1 EGC30349.1 - 0.97 9.3 8.2 6.4 6.7 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Kelch_4 PF13418.1 EGC30350.1 - 5e-44 147.8 14.7 3.3e-09 36.3 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC30350.1 - 4.5e-41 137.3 14.5 7e-09 35.4 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC30350.1 - 1.5e-39 133.3 5.8 3.3e-08 33.3 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC30350.1 - 1.1e-34 116.8 9.3 8.6e-09 34.8 0.3 6.7 6 1 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EGC30350.1 - 2.8e-34 116.3 24.9 4.4e-06 26.1 0.0 7.7 6 2 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGC30350.1 - 6.4e-34 115.3 13.8 2e-08 34.1 0.0 6.8 7 0 0 7 7 7 5 Galactose oxidase, central domain F-box-like PF12937.2 EGC30350.1 - 8.6e-12 44.5 0.1 1.7e-11 43.6 0.1 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC30350.1 - 7.6e-06 25.4 0.1 1.5e-05 24.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain PQQ_3 PF13570.1 EGC30350.1 - 0.00039 20.5 2.2 39 4.7 0.0 5.0 5 0 0 5 5 5 0 PQQ-like domain Complex1_LYR PF05347.10 EGC30351.1 - 4e-10 39.3 0.3 6.7e-10 38.6 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC30351.1 - 6.3e-09 35.9 0.2 1.2e-08 35.0 0.2 1.5 1 0 0 1 1 1 1 Complex1_LYR-like Cas_Csx8 PF09657.5 EGC30351.1 - 0.002 16.9 1.2 0.0022 16.7 0.8 1.1 1 0 0 1 1 1 1 CRISPR-associated protein Csx8 (Cas_Csx8) DUF3885 PF13021.1 EGC30351.1 - 0.029 14.0 0.5 0.16 11.7 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3885) PAP2 PF01569.16 EGC30352.1 - 1.9e-08 34.0 8.6 1.9e-08 34.0 6.0 2.8 2 2 0 2 2 2 1 PAP2 superfamily PAP2_3 PF14378.1 EGC30352.1 - 3.4e-08 33.2 1.6 3.4e-08 33.2 1.1 2.3 2 0 0 2 2 2 1 PAP2 superfamily PhoD PF09423.5 EGC30353.1 - 4.5e-07 28.7 0.5 7.2e-07 28.1 0.3 1.2 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.23 EGC30353.1 - 0.00043 19.7 0.7 0.0015 17.9 0.4 1.9 1 1 1 2 2 2 1 Calcineurin-like phosphoesterase Cytochrom_B_N PF00033.14 EGC30353.1 - 0.024 13.9 2.8 6 6.1 2.9 2.5 2 1 1 3 3 3 0 Cytochrome b(N-terminal)/b6/petB TH1 PF04858.8 EGC30354.1 - 3.1e-133 445.0 0.1 3.8e-133 444.7 0.1 1.0 1 0 0 1 1 1 1 TH1 protein GNAT_acetyltran PF12746.2 EGC30354.1 - 0.031 13.1 0.1 0.053 12.3 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase FNIP PF05725.7 EGC30355.1 - 2.7e-20 72.0 43.3 7.1e-08 32.2 2.4 10.4 10 1 0 10 10 10 5 FNIP Repeat Noggin PF05806.7 EGC30355.1 - 0.063 12.5 0.1 0.33 10.2 0.0 2.3 2 0 0 2 2 2 0 Noggin PARG_cat PF05028.9 EGC30355.1 - 0.067 12.4 0.5 0.17 11.1 0.2 1.6 1 1 1 2 2 2 0 Poly (ADP-ribose) glycohydrolase (PARG) Aminotran_1_2 PF00155.16 EGC30356.1 - 1.3e-96 323.7 0.0 1.5e-96 323.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Myb_DNA-binding PF00249.26 EGC30356.1 - 0.00076 19.4 0.2 0.024 14.6 0.0 2.8 3 0 0 3 3 3 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC30356.1 - 0.099 12.7 0.0 1.9 8.6 0.0 2.7 3 0 0 3 3 3 0 Myb-like DNA-binding domain DUF2043 PF09740.4 EGC30357.1 - 1.5e-29 102.2 0.0 1.5e-29 102.2 0.0 2.8 4 0 0 4 4 4 1 Uncharacterized conserved protein (DUF2043) HSBP1 PF06825.7 EGC30357.1 - 0.0017 17.8 0.0 0.0067 15.9 0.0 2.1 1 1 0 1 1 1 1 Heat shock factor binding protein 1 DUF3782 PF12644.2 EGC30357.1 - 0.036 13.8 0.9 0.093 12.5 0.6 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3782) Mucin PF01456.12 EGC30357.1 - 0.095 12.4 8.8 0.2 11.4 6.1 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF1980 PF09323.5 EGC30358.1 - 0.083 12.6 5.5 0.098 12.3 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Clr2 PF10383.4 EGC30358.1 - 0.091 12.7 1.3 0.1 12.6 0.9 1.1 1 0 0 1 1 1 0 Transcription-silencing protein Clr2 AhpC-TSA PF00578.16 EGC30359.1 - 4e-43 146.0 0.0 4.7e-43 145.8 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC30359.1 - 5.8e-27 94.0 0.0 7.1e-27 93.7 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EGC30359.1 - 6.2e-05 23.0 0.0 9.6e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.1 EGC30359.1 - 0.043 13.7 0.0 0.059 13.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme AAA_22 PF13401.1 EGC30360.1 - 1.9e-05 24.8 0.0 4.4e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGC30360.1 - 0.00078 19.3 0.1 0.011 15.6 0.0 2.6 2 1 1 3 3 3 1 AAA domain (Cdc48 subfamily) Torsin PF06309.6 EGC30360.1 - 0.0015 18.4 2.7 0.0058 16.5 0.2 3.1 3 1 0 3 3 3 1 Torsin AAA_5 PF07728.9 EGC30360.1 - 0.0016 18.1 0.2 0.0074 16.0 0.1 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGC30360.1 - 0.0035 17.5 0.0 0.01 16.0 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) HR1 PF02185.11 EGC30360.1 - 0.081 12.6 2.9 0.14 11.9 0.2 2.5 2 0 0 2 2 2 0 Hr1 repeat ABC_tran PF00005.22 EGC30360.1 - 1.9 8.7 4.7 1.2 9.4 1.5 2.3 2 1 0 2 2 2 0 ABC transporter SPA PF08616.5 EGC30361.1 - 4.1e-13 49.0 0.2 7.6e-13 48.1 0.1 1.5 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGC30361.1 - 4.2e-09 35.3 1.4 4.1e-05 22.2 0.1 2.2 1 1 1 2 2 2 2 Transport protein Avl9 DUF2347 PF09804.4 EGC30361.1 - 8.3e-08 31.8 0.6 8.1e-07 28.6 0.2 2.4 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2347) DENN PF02141.16 EGC30361.1 - 0.045 13.4 0.2 0.11 12.1 0.0 1.8 2 0 0 2 2 2 0 DENN (AEX-3) domain Cortex-I_coil PF09304.5 EGC30361.1 - 0.061 13.3 1.4 0.13 12.3 1.0 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil UBN2_2 PF14227.1 EGC30361.1 - 0.15 11.6 4.0 0.35 10.4 2.8 1.6 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type FANCI_S2 PF14676.1 EGC30363.1 - 0.55 10.1 11.1 1.3 8.9 0.6 3.3 2 1 1 3 3 3 0 FANCI solenoid 2 IF4E PF01652.13 EGC30364.1 - 1.5e-54 183.9 3.4 1.5e-54 183.9 2.4 1.5 2 0 0 2 2 2 1 Eukaryotic initiation factor 4E CotH PF08757.6 EGC30364.1 - 3.2e-05 23.3 6.7 3.9e-05 23.0 4.7 1.2 1 0 0 1 1 1 1 CotH protein Caldesmon PF02029.10 EGC30364.1 - 0.0012 17.3 8.5 0.0013 17.3 5.9 1.1 1 0 0 1 1 1 1 Caldesmon Dicty_REP PF05086.7 EGC30364.1 - 0.0021 15.9 4.7 0.0024 15.7 3.2 1.2 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein Tim54 PF11711.3 EGC30364.1 - 0.012 14.2 7.5 0.017 13.7 5.2 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 MecA PF05389.7 EGC30364.1 - 0.015 14.8 5.4 0.027 14.0 3.7 1.4 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) FimP PF09766.4 EGC30364.1 - 0.033 13.2 10.0 0.044 12.8 7.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein Folate_carrier PF01770.13 EGC30364.1 - 0.092 11.2 4.4 0.12 10.8 3.0 1.1 1 0 0 1 1 1 0 Reduced folate carrier DUF3530 PF12048.3 EGC30364.1 - 0.52 9.2 12.8 0.68 8.8 8.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) Pex14_N PF04695.8 EGC30364.1 - 0.54 10.3 7.4 1 9.4 5.1 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HSP70 PF00012.15 EGC30364.1 - 1.4 6.7 7.1 1.8 6.3 4.9 1.1 1 0 0 1 1 1 0 Hsp70 protein FAM176 PF14851.1 EGC30364.1 - 1.8 8.2 8.5 3.6 7.2 5.9 1.5 1 0 0 1 1 1 0 FAM176 family YqfQ PF14181.1 EGC30364.1 - 3.4 7.7 15.6 6.4 6.7 10.8 1.4 1 0 0 1 1 1 0 YqfQ-like protein RP-C_C PF11800.3 EGC30364.1 - 3.4 7.3 10.4 5.4 6.6 7.2 1.4 1 0 0 1 1 1 0 Replication protein C C-terminal region RR_TM4-6 PF06459.7 EGC30364.1 - 4.1 7.2 14.7 6.5 6.5 10.2 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DDHD PF02862.12 EGC30364.1 - 4.3 7.0 9.5 7 6.3 6.6 1.3 1 0 0 1 1 1 0 DDHD domain PBP1_TM PF14812.1 EGC30364.1 - 7.1 7.0 9.1 20 5.5 6.3 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CobT PF06213.7 EGC30364.1 - 8.7 5.3 13.7 14 4.7 9.5 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT MCM PF00493.18 EGC30365.1 - 1.9e-127 424.6 0.5 1e-126 422.2 0.0 2.2 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGC30365.1 - 4.9e-15 56.0 0.2 4.9e-15 56.0 0.1 2.5 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC30365.1 - 6.7e-09 35.2 0.1 4.9e-07 29.1 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGC30365.1 - 0.00076 19.1 0.0 0.0016 18.0 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGC30365.1 - 0.00076 18.9 0.0 0.0019 17.6 0.0 1.6 1 0 0 1 1 1 1 Sigma-54 interaction domain AAA_5 PF07728.9 EGC30365.1 - 0.0071 16.0 0.0 0.033 13.9 0.0 2.2 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) TEX19 PF15553.1 EGC30365.1 - 1.7 8.4 4.0 16 5.2 2.1 2.4 2 0 0 2 2 2 0 Testis-expressed protein 19 Menin PF05053.8 EGC30365.1 - 2 6.4 16.0 3.2 5.8 11.1 1.2 1 0 0 1 1 1 0 Menin Podoplanin PF05808.6 EGC30366.1 - 0.026 14.1 0.1 0.043 13.3 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF1191 PF06697.7 EGC30366.1 - 0.054 12.2 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) EphA2_TM PF14575.1 EGC30366.1 - 0.068 13.5 0.7 1.4 9.3 0.0 3.2 3 0 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain PhosphMutase PF10143.4 EGC30367.1 - 5e-58 195.5 0.0 7.4e-58 194.9 0.0 1.3 1 0 0 1 1 1 1 2,3-bisphosphoglycerate-independent phosphoglycerate mutase Metalloenzyme PF01676.13 EGC30367.1 - 3.9e-36 124.7 0.0 5.1e-36 124.3 0.0 1.1 1 0 0 1 1 1 1 Metalloenzyme superfamily Phosphodiest PF01663.17 EGC30367.1 - 2e-05 24.1 0.0 6e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 Type I phosphodiesterase / nucleotide pyrophosphatase HSP70 PF00012.15 EGC30368.1 - 4.4e-260 863.7 12.0 5e-260 863.5 8.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGC30368.1 - 1.1e-16 60.3 0.1 7.7e-14 51.0 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Hydantoinase_A PF01968.13 EGC30368.1 - 0.00023 20.3 1.0 0.013 14.5 0.1 3.1 2 1 1 3 3 3 1 Hydantoinase/oxoprolinase DDR PF08841.5 EGC30368.1 - 0.0041 15.9 0.2 0.14 10.9 0.0 2.4 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain FGGY_C PF02782.11 EGC30368.1 - 0.0044 16.6 0.0 0.0091 15.6 0.0 1.5 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, C-terminal domain FtsA PF14450.1 EGC30368.1 - 3.2 7.5 13.7 0.38 10.5 0.6 4.5 3 3 0 3 3 3 0 Cell division protein FtsA EGF_2 PF07974.8 EGC30370.1 - 0.017 15.2 9.7 0.037 14.1 6.7 1.6 1 0 0 1 1 1 0 EGF-like domain NARP1 PF12569.3 EGC30371.1 - 0.1 11.3 12.6 0.17 10.6 8.7 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DDHD PF02862.12 EGC30371.1 - 0.12 12.2 10.0 0.19 11.4 6.9 1.3 1 0 0 1 1 1 0 DDHD domain TLP-20 PF06088.6 EGC30371.1 - 0.18 11.4 9.7 0.29 10.8 6.7 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) FHIPEP PF00771.15 EGC30371.1 - 0.29 9.4 1.1 0.4 8.9 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF1510 PF07423.6 EGC30371.1 - 0.29 10.4 15.5 0.45 9.8 10.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) SSURE PF11966.3 EGC30371.1 - 0.55 9.8 3.4 3.9 7.1 0.0 3.0 2 1 1 3 3 3 0 Fibronectin-binding repeat Vfa1 PF08432.5 EGC30371.1 - 0.56 10.2 15.0 0.024 14.6 6.6 1.5 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 LNP1 PF15419.1 EGC30371.1 - 1.1 9.3 10.2 1.7 8.7 7.1 1.2 1 0 0 1 1 1 0 Leukemia NUP98 fusion partner 1 Daxx PF03344.10 EGC30371.1 - 1.2 7.5 15.2 1.7 7.0 10.5 1.1 1 0 0 1 1 1 0 Daxx Family SR-25 PF10500.4 EGC30371.1 - 1.4 8.3 16.9 2.2 7.6 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein FAM176 PF14851.1 EGC30371.1 - 2 8.0 7.6 4 7.1 5.3 1.5 1 0 0 1 1 1 0 FAM176 family Pilt PF15453.1 EGC30371.1 - 2.1 7.9 7.9 2.9 7.5 5.5 1.1 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions SprA-related PF12118.3 EGC30371.1 - 3.8 6.7 15.1 5.1 6.3 10.5 1.1 1 0 0 1 1 1 0 SprA-related family Serinc PF03348.10 EGC30371.1 - 3.9 6.0 6.1 6.4 5.3 4.2 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) Pox_Ag35 PF03286.9 EGC30371.1 - 9.3 5.7 15.5 15 5.0 10.7 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein WD40 PF00400.27 EGC30372.1 - 2.1e-17 62.2 12.9 3.1e-08 33.1 0.0 5.9 5 0 0 5 5 5 5 WD domain, G-beta repeat F-box-like PF12937.2 EGC30372.1 - 3.4e-09 36.2 0.7 8.6e-09 34.9 0.0 2.1 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC30372.1 - 4.8e-09 35.6 0.6 2e-08 33.6 0.3 2.2 2 0 0 2 2 2 1 F-box domain Nup160 PF11715.3 EGC30372.1 - 2.7e-06 25.8 5.5 0.027 12.6 0.2 3.8 3 1 1 4 4 4 3 Nucleoporin Nup120/160 Pox_A31 PF05771.6 EGC30374.1 - 0.052 13.3 0.2 0.062 13.1 0.2 1.1 1 0 0 1 1 1 0 Poxvirus A31 protein EGF_2 PF07974.8 EGC30375.1 - 1.6e-05 24.9 31.2 0.00037 20.5 8.1 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC30375.1 - 0.00024 20.9 11.4 0.041 13.9 1.2 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC30375.1 - 0.067 13.1 22.0 1.2 9.1 5.3 2.8 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) DUF3344 PF11824.3 EGC30376.1 - 0.0038 16.6 0.3 0.0042 16.5 0.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3344) EGF_2 PF07974.8 EGC30377.1 - 9.3e-07 28.9 31.6 0.0002 21.4 8.1 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC30377.1 - 0.00026 20.8 11.4 0.042 13.9 1.2 3.1 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC30377.1 - 0.19 11.6 22.7 1.8 8.5 6.1 2.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC30378.1 - 9.4e-06 25.6 31.2 0.00021 21.4 8.1 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC30378.1 - 0.0023 17.9 14.8 0.044 13.8 1.2 3.4 3 0 0 3 3 3 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC30378.1 - 0.16 11.9 23.8 0.77 9.7 5.8 2.7 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC30379.1 - 5.2e-06 26.5 46.3 0.00098 19.2 7.5 4.1 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.2 EGC30379.1 - 0.033 14.2 1.7 0.033 14.2 1.2 4.1 4 0 0 4 4 4 0 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC30379.1 - 0.81 9.6 36.3 2.3 8.2 4.8 3.9 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) Folliculin PF11704.3 EGC30381.1 - 4.4e-45 153.2 0.8 4.4e-45 153.2 0.6 2.5 2 0 0 2 2 2 1 Vesicle coat protein involved in Golgi to plasma membrane transport DUF3439 PF11921.3 EGC30381.1 - 1.1 9.0 8.1 3 7.6 5.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LSM PF01423.17 EGC30382.1 - 6.5e-15 54.4 0.5 1e-14 53.8 0.4 1.3 1 0 0 1 1 1 1 LSM domain Cofilin_ADF PF00241.15 EGC30383.1 - 3.4e-12 46.3 0.0 4.1e-12 46.0 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein LIM PF00412.17 EGC30384.1 - 1.2e-12 47.6 7.8 1.7e-12 47.2 5.4 1.2 1 0 0 1 1 1 1 LIM domain DUF4428 PF14471.1 EGC30384.1 - 0.0085 15.8 1.2 0.0085 15.8 0.8 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF4428) zf-C3HC4_2 PF13923.1 EGC30384.1 - 0.15 12.0 5.1 6.3 6.9 1.8 2.6 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) GCC2_GCC3 PF07699.8 EGC30384.1 - 0.43 10.2 7.9 2.1 7.9 3.9 2.4 1 1 1 2 2 2 0 GCC2 and GCC3 zf-UBR PF02207.15 EGC30384.1 - 0.94 9.2 7.3 1.6 8.5 5.1 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) TNFR_c6 PF00020.13 EGC30384.1 - 2.7 8.1 10.6 1.3 9.1 0.9 3.0 2 1 1 3 3 3 0 TNFR/NGFR cysteine-rich region C6_DPF PF10170.4 EGC30384.1 - 3.1 7.8 8.7 0.48 10.5 2.1 2.0 1 1 1 2 2 2 0 Cysteine-rich domain NCD3G PF07562.9 EGC30384.1 - 3.8 7.3 8.6 6.3 6.6 4.7 2.2 1 1 0 1 1 1 0 Nine Cysteines Domain of family 3 GPCR zf-met PF12874.2 EGC30384.1 - 4.5 7.6 10.2 9 6.6 0.2 3.3 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-CXXC PF02008.15 EGC30384.1 - 6.9 6.5 7.9 9.5 6.1 2.9 2.7 2 1 1 3 3 3 0 CXXC zinc finger domain C1_1 PF00130.17 EGC30384.1 - 7.3 6.4 11.0 5.8 6.7 2.7 3.0 1 1 2 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Desulfoferrod_N PF06397.7 EGC30384.1 - 8.2 5.9 6.6 3.1 7.2 1.0 2.2 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain TIG PF01833.19 EGC30386.1 - 7.6e-06 25.8 1.6 0.0043 17.0 0.4 2.4 2 0 0 2 2 2 2 IPT/TIG domain EGF_2 PF07974.8 EGC30386.1 - 0.031 14.4 14.3 0.031 14.4 9.9 3.1 3 0 0 3 3 3 0 EGF-like domain Laminin_EGF PF00053.19 EGC30386.1 - 0.21 11.5 0.2 0.21 11.5 0.1 2.7 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) SNARE PF05739.14 EGC30388.1 - 6.1e-09 35.4 4.8 9.4e-09 34.8 3.4 1.3 1 0 0 1 1 1 1 SNARE domain IncA PF04156.9 EGC30388.1 - 0.00073 19.1 2.2 0.00091 18.8 1.5 1.2 1 0 0 1 1 1 1 IncA protein Reo_sigmaC PF04582.7 EGC30388.1 - 0.014 14.5 3.8 0.017 14.2 2.6 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Atg14 PF10186.4 EGC30388.1 - 0.025 13.5 0.4 0.032 13.1 0.3 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Tropomyosin PF00261.15 EGC30388.1 - 0.037 13.1 0.2 0.053 12.5 0.1 1.3 1 0 0 1 1 1 0 Tropomyosin DUF1664 PF07889.7 EGC30388.1 - 0.04 13.7 2.9 0.054 13.3 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EGC30388.1 - 0.048 12.3 4.1 0.053 12.1 2.8 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 EGC30388.1 - 0.059 13.4 2.6 0.098 12.7 1.7 1.5 1 1 0 1 1 1 0 DivIVA protein FliJ PF02050.11 EGC30388.1 - 0.12 12.4 1.8 0.16 12.0 0.8 1.5 1 1 0 1 1 1 0 Flagellar FliJ protein DUF745 PF05335.8 EGC30388.1 - 0.22 11.0 1.5 0.27 10.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF745) NPV_P10 PF05531.7 EGC30388.1 - 0.23 11.7 4.0 0.38 11.0 2.8 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus P10 protein DUF948 PF06103.6 EGC30388.1 - 0.26 11.1 3.9 0.41 10.5 2.7 1.3 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) CENP-Q PF13094.1 EGC30388.1 - 0.37 10.8 5.5 2 8.4 0.1 2.3 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Tropomyosin_1 PF12718.2 EGC30388.1 - 0.42 10.4 4.2 0.77 9.6 2.8 1.6 1 1 0 1 1 1 0 Tropomyosin like Ank_3 PF13606.1 EGC30391.1 - 0.00015 21.6 13.0 0.65 10.4 0.0 8.3 9 1 1 10 10 10 1 Ankyrin repeat Ank_2 PF12796.2 EGC30391.1 - 0.0002 21.6 12.6 0.033 14.5 0.0 4.7 3 3 1 4 4 4 2 Ankyrin repeats (3 copies) Methyltransf_12 PF08242.7 EGC30391.1 - 4 7.9 16.5 2.3 8.7 1.2 3.8 3 0 0 3 3 3 0 Methyltransferase domain NigD PF12667.2 EGC30392.1 - 0.032 14.0 0.2 0.035 13.9 0.1 1.2 1 0 0 1 1 1 0 NigD-like protein Arrestin_C PF02752.17 EGC30392.1 - 0.075 13.1 1.0 0.09 12.8 0.7 1.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain Selenoprotein_S PF06936.6 EGC30394.1 - 8.1 5.9 10.7 0.4 10.1 1.1 2.6 3 0 0 3 3 3 0 Selenoprotein S (SelS) ubiquitin PF00240.18 EGC30395.1 - 8.5e-05 21.8 0.1 0.00011 21.4 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGC30395.1 - 0.0022 18.2 0.0 0.0033 17.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like domain Dioxygenase_C PF00775.16 EGC30395.1 - 0.094 11.9 0.0 0.1 11.8 0.0 1.1 1 0 0 1 1 1 0 Dioxygenase BMP2K_C PF15282.1 EGC30397.1 - 0.29 11.2 3.8 0.29 11.2 2.6 1.0 1 0 0 1 1 1 0 BMP-2-inducible protein kinase C-terminus SEA PF01390.15 EGC30398.1 - 0.00058 19.5 0.4 0.0017 17.9 0.0 1.9 2 0 0 2 2 2 1 SEA domain RhoGEF PF00621.15 EGC30399.1 - 1.2e-47 162.1 7.5 1.2e-47 162.1 5.2 3.4 3 1 0 3 3 3 1 RhoGEF domain CH PF00307.26 EGC30399.1 - 1.5e-12 47.4 0.2 9.7e-12 44.8 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain CDC24 PF06395.6 EGC30399.1 - 0.00026 21.0 0.6 0.00081 19.4 0.1 2.2 2 0 0 2 2 2 1 CDC24 Calponin IQ PF00612.22 EGC30399.1 - 0.011 15.3 2.0 0.031 13.9 1.4 1.8 1 0 0 1 1 1 0 IQ calmodulin-binding motif CAMSAP_CH PF11971.3 EGC30399.1 - 0.015 14.9 0.0 0.049 13.2 0.0 1.9 1 0 0 1 1 1 0 CAMSAP CH domain RRM_1 PF00076.17 EGC30400.1 - 3.6e-17 61.7 0.0 4.2e-17 61.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC30400.1 - 2.6e-11 43.3 0.0 3.1e-11 43.1 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC30400.1 - 8e-05 22.4 0.0 0.0003 20.5 0.0 1.7 1 1 1 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RabGAP-TBC PF00566.13 EGC30401.1 - 5.4e-52 176.3 3.3 5.4e-52 176.3 2.3 4.0 4 1 1 5 5 5 1 Rab-GTPase-TBC domain EF-hand_1 PF00036.27 EGC30402.1 - 7.5e-18 62.4 1.6 9e-07 27.7 0.1 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGC30402.1 - 6.3e-16 56.7 0.7 4.5e-07 29.2 0.0 3.5 2 1 2 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EGC30402.1 - 9.9e-15 54.4 0.3 1.8e-07 31.1 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC30402.1 - 7.2e-09 35.1 3.1 0.00056 19.4 0.2 2.8 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_9 PF14658.1 EGC30402.1 - 1.4e-05 24.9 0.0 0.00016 21.4 0.0 2.4 1 1 2 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EGC30402.1 - 0.00012 21.2 3.0 0.00027 20.1 0.1 2.8 3 0 0 3 3 3 1 EF hand DUF3349 PF11829.3 EGC30402.1 - 0.0022 18.3 0.2 3.3 8.1 0.0 2.5 2 1 0 2 2 2 2 Protein of unknown function (DUF3349) Orthopox_B11R PF07033.6 EGC30402.1 - 0.012 15.1 3.4 0.014 14.8 0.4 2.3 3 0 0 3 3 3 0 Orthopoxvirus B11R protein Poly_export PF02563.11 EGC30402.1 - 0.02 14.6 0.0 0.13 12.0 0.0 2.2 3 0 0 3 3 3 0 Polysaccharide biosynthesis/export protein EF-hand_4 PF12763.2 EGC30402.1 - 0.023 14.4 0.3 6.7 6.4 0.0 2.2 2 0 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand EFhand_Ca_insen PF08726.5 EGC30402.1 - 0.07 13.1 0.2 0.63 10.0 0.0 2.2 2 0 0 2 2 2 0 Ca2+ insensitive EF hand UPF0154 PF03672.8 EGC30402.1 - 0.13 11.8 0.0 6.6 6.4 0.0 2.8 2 1 1 3 3 3 0 Uncharacterised protein family (UPF0154) Steroid_dh PF02544.11 EGC30403.1 - 9e-25 87.1 7.1 9e-25 87.1 4.9 2.5 2 1 1 3 3 3 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EGC30403.1 - 0.027 14.5 0.2 0.027 14.5 0.1 3.0 3 0 0 3 3 3 0 Phospholipid methyltransferase DUF2615 PF11027.3 EGC30403.1 - 0.13 12.1 0.4 2.5 8.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2615) MFS_1 PF07690.11 EGC30403.1 - 2.7 6.6 7.8 0.43 9.2 0.1 2.3 2 1 0 2 2 2 0 Major Facilitator Superfamily MOSC_N PF03476.11 EGC30404.1 - 5.2e-19 68.1 0.0 9.1e-19 67.3 0.0 1.3 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGC30404.1 - 1.9e-10 40.3 0.0 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 MOSC domain UQ_con PF00179.21 EGC30405.1 - 2.7e-22 78.7 0.2 4.5e-22 77.9 0.2 1.4 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Hydrolase_2 PF07486.7 EGC30405.1 - 0.28 11.7 1.9 0.24 11.9 0.2 1.8 2 0 0 2 2 2 0 Cell Wall Hydrolase DUF4065 PF13274.1 EGC30405.1 - 1.2 9.8 7.5 0.23 12.1 2.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF4065) AMP-binding PF00501.23 EGC30406.1 - 5.3e-77 258.9 0.0 7.3e-77 258.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC30406.1 - 5.9e-08 33.5 0.0 1.3e-07 32.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain ETF PF01012.16 EGC30407.1 - 6.1e-43 146.3 0.4 8.8e-43 145.8 0.3 1.2 1 0 0 1 1 1 1 Electron transfer flavoprotein domain TPT PF03151.11 EGC30408.1 - 1.5e-14 53.9 32.3 3.8e-14 52.6 10.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGC30408.1 - 1e-07 31.1 32.0 2.1e-07 30.1 22.2 1.4 1 1 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGC30408.1 - 0.00012 22.1 32.5 0.00067 19.6 8.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGC30408.1 - 0.017 15.3 6.4 0.017 15.3 4.4 2.6 2 1 0 2 2 2 0 Multidrug resistance efflux transporter Nodulin-like PF06813.8 EGC30408.1 - 1.1 8.4 24.2 0.44 9.7 5.2 2.5 1 1 0 2 2 2 0 Nodulin-like DUF3430 PF11912.3 EGC30409.1 - 1.2e-17 64.4 32.8 1.5e-17 64.1 22.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC30409.1 - 0.005 16.8 10.3 0.017 15.1 1.7 3.1 2 1 1 3 3 3 2 Protein of unknown function (DUF3586) DUF3718 PF12514.3 EGC30409.1 - 0.29 11.1 3.0 11 6.1 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3718) Ras PF00071.17 EGC30410.1 - 8.9e-55 184.4 0.0 1e-54 184.2 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30410.1 - 4.2e-17 62.7 0.0 6e-17 62.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30410.1 - 1.8e-09 37.0 0.0 2.3e-09 36.7 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC30410.1 - 9.3e-05 21.9 0.0 0.00084 18.8 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain RRM_1 PF00076.17 EGC30411.1 - 4.3e-45 151.2 1.1 4.1e-20 71.1 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC30411.1 - 1.7e-29 101.4 4.1 4.2e-11 42.5 0.0 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC30411.1 - 4.6e-28 96.9 0.3 8.7e-12 44.8 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC30411.1 - 7.6e-07 28.9 0.0 0.0046 16.7 0.0 3.2 3 0 0 3 3 3 2 RNA binding motif Limkain-b1 PF11608.3 EGC30411.1 - 0.002 17.8 0.0 0.73 9.6 0.0 3.2 3 0 0 3 3 3 1 Limkain b1 Nup35_RRM_2 PF14605.1 EGC30411.1 - 0.071 12.8 0.1 0.28 10.9 0.0 2.1 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif Rad9 PF04139.8 EGC30412.1 - 0.068 12.2 0.1 0.076 12.1 0.1 1.0 1 0 0 1 1 1 0 Rad9 Med23 PF11573.3 EGC30414.1 - 5.7e-42 143.2 29.6 5.7e-42 143.2 20.5 1.5 2 0 0 2 2 2 1 Mediator complex subunit 23 Patched PF02460.13 EGC30415.1 - 2.5e-93 313.4 10.4 2.6e-93 313.4 6.7 1.3 1 1 0 1 1 1 1 Patched family Sterol-sensing PF12349.3 EGC30415.1 - 1.4e-48 164.2 32.8 1.6e-48 164.0 3.8 3.3 3 0 0 3 3 3 2 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EGC30415.1 - 0.79 7.0 17.8 1.3 6.3 12.4 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family MMPL PF03176.10 EGC30415.1 - 1.4 7.5 29.6 0.57 8.8 5.6 2.7 2 0 0 2 2 2 0 MMPL family Pkinase PF00069.20 EGC30416.1 - 3.3e-69 232.9 0.0 4.7e-69 232.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30416.1 - 2.6e-50 170.9 0.0 3.7e-50 170.4 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC30416.1 - 1.7e-05 23.9 0.0 9.2e-05 21.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like DUF573 PF04504.9 EGC30416.1 - 0.012 15.9 0.5 0.039 14.2 0.3 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF573 DUF4611 PF15387.1 EGC30416.1 - 0.023 14.8 9.8 0.25 11.5 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EGC30416.1 - 0.15 11.8 7.1 0.24 11.1 1.8 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal PBP1_TM PF14812.1 EGC30416.1 - 0.33 11.2 12.8 2.1 8.7 5.3 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Nucleoplasmin PF03066.10 EGC30416.1 - 1.1 8.7 16.8 0.17 11.3 3.2 2.6 3 0 0 3 3 3 0 Nucleoplasmin FAM176 PF14851.1 EGC30416.1 - 2.1 8.0 10.6 3.2 7.4 1.8 2.3 2 0 0 2 2 2 0 FAM176 family FimP PF09766.4 EGC30418.1 - 9.8e-59 199.1 41.1 1e-56 192.5 25.1 3.4 2 1 0 2 2 2 2 Fms-interacting protein RWD PF05773.17 EGC30418.1 - 0.0048 16.7 1.2 0.0048 16.7 0.8 2.7 2 2 0 2 2 2 1 RWD domain UEV PF05743.8 EGC30418.1 - 0.007 16.0 0.2 0.021 14.4 0.1 1.8 2 0 0 2 2 2 1 UEV domain MFS_1 PF07690.11 EGC30419.1 - 1.2e-10 40.6 18.6 1.6e-10 40.2 12.9 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGC30419.1 - 0.031 12.6 16.8 0.11 10.8 11.6 1.8 1 1 0 1 1 1 0 MFS/sugar transport protein Sugar_tr PF00083.19 EGC30419.1 - 0.18 10.3 17.1 1.4 7.3 11.8 2.3 1 1 0 1 1 1 0 Sugar (and other) transporter AA_permease_2 PF13520.1 EGC30420.1 - 0.0038 15.8 2.1 0.0049 15.4 1.4 1.1 1 0 0 1 1 1 1 Amino acid permease Sulfate_transp PF00916.15 EGC30420.1 - 0.038 12.9 0.4 0.047 12.7 0.3 1.1 1 0 0 1 1 1 0 Sulfate transporter family Cation_ATPase_C PF00689.16 EGC30420.1 - 0.11 12.0 1.7 0.16 11.4 1.2 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus DUF3753 PF12575.3 EGC30420.1 - 0.22 11.3 6.6 0.73 9.6 1.9 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) LicD PF04991.8 EGC30420.1 - 0.27 11.3 6.8 0.35 10.9 4.7 1.1 1 0 0 1 1 1 0 LicD family DUF2360 PF10152.4 EGC30420.1 - 1.4 9.1 9.0 0.57 10.4 3.8 1.9 2 0 0 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF972 PF06156.8 EGC30420.1 - 1.6 9.1 6.5 1.6 9.1 1.8 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF972) Pex14_N PF04695.8 EGC30420.1 - 8.7 6.3 11.6 15 5.6 8.1 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Kinesin PF00225.18 EGC30421.1 - 3.1e-14 52.4 0.2 3.4e-14 52.3 0.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain DUF3767 PF12597.3 EGC30422.1 - 6.3e-16 58.1 0.0 7.8e-16 57.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3767) PP28 PF10252.4 EGC30422.1 - 0.041 13.9 4.0 0.066 13.2 2.8 1.3 1 0 0 1 1 1 0 Casein kinase substrate phosphoprotein PP28 Arf PF00025.16 EGC30424.1 - 4.6e-66 221.3 0.1 5.6e-66 221.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC30424.1 - 1.8e-14 53.4 0.0 2.2e-14 53.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC30424.1 - 4e-12 45.7 0.0 4.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC30424.1 - 5.2e-10 38.5 2.2 1.9e-07 30.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGC30424.1 - 1e-08 35.6 0.0 1.5e-08 35.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC30424.1 - 3.4e-08 32.9 0.0 4.2e-08 32.6 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC30424.1 - 0.0003 20.7 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase Me-amine-dh_H PF06433.6 EGC30424.1 - 0.03 12.9 0.0 0.039 12.6 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) ArgK PF03308.11 EGC30424.1 - 0.03 13.0 0.1 0.42 9.3 0.0 2.1 2 0 0 2 2 2 0 ArgK protein SRP54 PF00448.17 EGC30424.1 - 0.04 13.3 0.1 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EGC30424.1 - 0.1 12.4 0.1 0.17 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC30424.1 - 0.13 12.5 0.7 0.32 11.2 0.5 1.8 1 1 0 1 1 1 0 ABC transporter AMP-binding PF00501.23 EGC30425.1 - 1.7e-64 217.7 0.0 2.4e-64 217.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme NAD_binding_4 PF07993.7 EGC30425.1 - 2.8e-46 157.4 0.0 8.5e-46 155.8 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGC30425.1 - 5.7e-07 29.2 0.1 1.7e-05 24.3 0.0 2.7 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family ZZ PF00569.12 EGC30425.1 - 0.00011 21.6 10.5 0.00022 20.7 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, ZZ type PP-binding PF00550.20 EGC30425.1 - 0.00019 21.6 0.3 0.00045 20.4 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site TFIIA PF03153.8 EGC30427.1 - 0.00027 20.9 10.7 0.00031 20.7 7.4 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit AUX_IAA PF02309.11 EGC30427.1 - 0.1 12.3 9.2 0.17 11.6 6.4 1.3 1 0 0 1 1 1 0 AUX/IAA family DUF4557 PF15101.1 EGC30427.1 - 0.14 11.9 11.8 0.22 11.3 8.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) BAF1_ABF1 PF04684.8 EGC30427.1 - 0.22 10.3 20.6 0.32 9.7 14.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor MCPVI PF02993.9 EGC30427.1 - 0.44 10.6 9.0 0.66 10.0 6.3 1.2 1 0 0 1 1 1 0 Minor capsid protein VI DUF4175 PF13779.1 EGC30427.1 - 0.44 8.1 25.2 0.54 7.9 17.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Band_3_cyto PF07565.8 EGC30427.1 - 1.4 8.4 11.3 0.64 9.4 5.1 2.0 2 0 0 2 2 2 0 Band 3 cytoplasmic domain Pex14_N PF04695.8 EGC30427.1 - 2.2 8.3 14.8 4.8 7.2 10.3 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Neur_chan_memb PF02932.11 EGC30427.1 - 2.4 7.9 5.8 4.4 7.1 4.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 EGC30427.1 - 2.6 6.1 31.1 3.6 5.6 21.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_S49_N PF08496.5 EGC30427.1 - 4.3 7.1 11.8 9.7 5.9 8.2 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal mRNA_cap_enzyme PF01331.14 EGC30428.1 - 8e-36 123.5 3.3 1.8e-35 122.3 2.3 1.6 1 0 0 1 1 1 1 mRNA capping enzyme, catalytic domain mRNA_triPase PF02940.10 EGC30428.1 - 8.2e-18 64.9 4.4 9.1e-17 61.5 3.1 2.3 1 1 0 1 1 1 1 mRNA capping enzyme, beta chain mRNA_cap_C PF03919.10 EGC30428.1 - 2e-09 37.7 0.4 2e-09 37.7 0.3 2.6 3 0 0 3 3 3 1 mRNA capping enzyme, C-terminal domain DNA_ligase_A_M PF01068.16 EGC30428.1 - 8.6e-07 28.5 0.5 0.00016 21.1 0.4 2.6 1 1 0 1 1 1 1 ATP dependent DNA ligase domain Pox_ATPase-GT PF10640.4 EGC30428.1 - 0.00015 20.7 2.2 0.00023 20.0 1.5 1.3 1 0 0 1 1 1 1 mRNA capping enzyme N-terminal, ATPase and guanylyltransferase LON PF02190.11 EGC30428.1 - 0.052 13.2 0.2 0.12 11.9 0.1 1.7 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain Rho_N PF07498.7 EGC30429.1 - 0.00063 19.4 0.5 0.0016 18.1 0.4 1.8 1 0 0 1 1 1 1 Rho termination factor, N-terminal domain GLTP PF08718.6 EGC30429.1 - 0.053 13.5 1.4 0.15 12.0 1.0 1.7 1 0 0 1 1 1 0 Glycolipid transfer protein (GLTP) MFS_1 PF07690.11 EGC30430.1 - 7.5e-31 107.1 54.4 1.7e-23 82.8 25.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC30430.1 - 1.7e-07 30.2 4.6 1.7e-07 30.2 3.2 3.6 2 2 2 4 4 4 2 Sugar (and other) transporter YcxB PF14317.1 EGC30430.1 - 0.12 11.6 0.2 0.25 10.5 0.1 1.5 1 0 0 1 1 1 0 YcxB-like protein PsbI PF02532.9 EGC30430.1 - 9.8 5.8 11.4 0.55 9.8 3.8 2.1 2 0 0 2 2 2 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) PhnA_Zn_Ribbon PF08274.7 EGC30431.1 - 0.0028 17.3 6.1 0.76 9.6 0.1 2.6 2 0 0 2 2 2 2 PhnA Zinc-Ribbon Zn_Tnp_IS1595 PF12760.2 EGC30431.1 - 0.0056 16.4 21.6 0.097 12.4 3.8 2.3 2 0 0 2 2 2 2 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 EGC30431.1 - 0.26 11.1 5.6 0.67 9.8 0.5 2.8 2 0 0 2 2 2 0 Ribosomal L37ae protein family zf-Dof PF02701.10 EGC30431.1 - 0.31 11.0 10.2 0.82 9.6 0.4 2.9 2 1 0 2 2 2 0 Dof domain, zinc finger PADR1 PF08063.7 EGC30431.1 - 3.9 6.9 9.3 9 5.7 2.2 2.3 2 0 0 2 2 2 0 PADR1 (NUC008) domain HORMA PF02301.13 EGC30432.1 - 3.5e-12 46.2 21.5 1.7e-10 40.7 14.9 2.8 1 1 0 1 1 1 1 HORMA domain Pkinase_Tyr PF07714.12 EGC30433.1 - 5.3e-63 212.5 0.0 1.1e-62 211.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30433.1 - 5.1e-58 196.2 0.5 3e-57 193.7 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain MORN PF02493.15 EGC30433.1 - 0.00026 20.5 2.6 0.46 10.3 0.3 3.4 3 0 0 3 3 3 2 MORN repeat APH PF01636.18 EGC30433.1 - 0.0091 15.7 0.0 0.017 14.8 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC30433.1 - 0.074 12.1 0.1 0.21 10.6 0.0 1.7 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Abi PF02517.11 EGC30434.1 - 7.3e-06 26.0 11.9 7.3e-06 26.0 8.2 2.7 2 1 1 3 3 3 1 CAAX protease self-immunity DUF2962 PF11176.3 EGC30435.1 - 4.2e-23 81.6 8.4 1.9e-12 47.0 3.9 2.0 1 1 1 2 2 2 2 Protein of unknown function (DUF2962) Ribosomal_L28e PF01778.12 EGC30436.1 - 1.7e-27 96.1 4.3 2.1e-27 95.8 3.0 1.1 1 0 0 1 1 1 1 Ribosomal L28e protein family CBM49 PF09478.5 EGC30437.1 - 2.1e-16 59.7 0.0 2.8e-16 59.3 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 bZIP_1 PF00170.16 EGC30439.1 - 3.2e-13 49.4 9.8 9.9e-13 47.8 6.8 1.9 1 0 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGC30439.1 - 4.8e-07 29.4 7.2 4.8e-07 29.4 5.0 3.3 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.12 EGC30439.1 - 1.4e-05 25.3 9.0 1.4e-05 25.3 6.2 2.5 2 0 0 2 2 2 1 bZIP Maf transcription factor DUF972 PF06156.8 EGC30439.1 - 0.059 13.7 1.0 0.059 13.7 0.7 3.4 2 1 1 3 3 3 0 Protein of unknown function (DUF972) RasGEF PF00617.14 EGC30440.1 - 9.7e-57 191.7 0.1 9.7e-57 191.7 0.1 3.2 4 0 0 4 4 4 1 RasGEF domain RCC1 PF00415.13 EGC30440.1 - 1.7e-43 146.5 9.3 2.6e-12 46.7 0.0 7.5 8 0 0 8 8 8 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC30440.1 - 1.1e-30 104.5 16.3 2e-09 36.7 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.15 EGC30440.1 - 1.2e-21 77.3 8.5 1.7e-21 76.9 0.7 3.2 3 0 0 3 3 3 1 RhoGEF domain RasGEF_N PF00618.15 EGC30440.1 - 2.3e-21 75.8 1.3 2.3e-21 75.8 0.9 4.3 3 2 1 4 4 4 1 RasGEF N-terminal motif WD40 PF00400.27 EGC30441.1 - 3.9e-42 140.6 13.0 3.1e-07 30.0 0.5 7.0 7 0 0 7 7 7 6 WD domain, G-beta repeat PQQ_2 PF13360.1 EGC30441.1 - 0.00079 18.9 0.0 0.0016 17.9 0.0 1.6 1 1 0 1 1 1 1 PQQ-like domain DUF3312 PF11768.3 EGC30441.1 - 0.0015 16.8 0.0 0.033 12.4 0.0 2.6 1 1 1 3 3 3 1 Protein of unknown function (DUF3312) Nucleoporin_N PF08801.6 EGC30441.1 - 0.028 13.1 5.0 3 6.4 0.2 3.2 1 1 2 3 3 3 0 Nup133 N terminal like Nbas_N PF15492.1 EGC30441.1 - 0.066 12.3 0.1 3.5 6.6 0.0 2.9 2 1 0 3 3 3 0 Neuroblastoma-amplified sequence, N terminal Ras PF00071.17 EGC30442.1 - 8e-21 74.0 0.6 1.2e-20 73.5 0.4 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30442.1 - 2.9e-11 43.9 0.5 5.2e-11 43.0 0.3 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30442.1 - 9.8e-08 31.4 0.3 1.6e-07 30.7 0.2 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC30442.1 - 0.001 18.9 1.4 0.001 18.9 1.0 1.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC30442.1 - 0.037 13.4 0.3 4.8 6.5 0.0 2.2 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EGC30442.1 - 0.071 13.0 5.3 0.039 13.8 1.7 2.0 1 1 1 2 2 2 0 AAA domain MobB PF03205.9 EGC30442.1 - 0.29 10.8 1.9 4.8 6.8 0.0 2.5 1 1 1 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PIP5K PF01504.13 EGC30444.1 - 9.7e-57 191.9 2.6 1.2e-56 191.6 1.8 1.0 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Kinesin PF00225.18 EGC30445.1 - 1.3e-59 201.6 2.3 3.1e-38 131.3 0.0 2.9 1 1 1 2 2 2 2 Kinesin motor domain LAG1-DNAbind PF09271.6 EGC30445.1 - 0.013 15.9 1.6 0.51 10.8 0.0 2.7 2 2 0 2 2 2 0 LAG1, DNA binding BRCT PF00533.21 EGC30447.1 - 1.2e-12 47.7 4.2 1.9e-12 47.1 0.8 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC30447.1 - 0.0047 16.7 0.1 0.01 15.6 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain Med3 PF11593.3 EGC30449.1 - 0.00023 20.5 4.2 0.00045 19.5 2.9 1.5 1 0 0 1 1 1 1 Mediator complex subunit 3 fungal UPF0542 PF15086.1 EGC30449.1 - 0.0047 16.6 0.1 0.0099 15.5 0.1 1.5 1 0 0 1 1 1 1 Uncharacterised protein family UPF0542 Metallophos_C PF14008.1 EGC30449.1 - 0.021 14.8 1.4 0.077 13.0 1.0 2.1 1 0 0 1 1 1 0 Iron/zinc purple acid phosphatase-like protein C Mem_trans PF03547.13 EGC30449.1 - 0.041 12.1 11.2 0.0025 16.1 3.1 2.0 2 0 0 2 2 2 0 Membrane transport protein PEX11 PF05648.9 EGC30449.1 - 0.13 11.5 1.2 0.24 10.6 0.9 1.4 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Jiraiya PF15038.1 EGC30449.1 - 0.3 10.5 0.8 0.59 9.5 0.6 1.4 1 0 0 1 1 1 0 Jiraiya DUF1824 PF08854.5 EGC30449.1 - 3.8 7.1 7.5 7.5 6.1 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1824) Pkinase_Tyr PF07714.12 EGC30451.1 - 2e-47 161.4 0.0 6.3e-31 107.3 0.0 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGC30451.1 - 4.6e-47 160.3 1.1 3.4e-45 154.2 0.0 3.5 3 1 0 3 3 3 1 Protein kinase domain RhoGEF PF00621.15 EGC30451.1 - 4.4e-21 75.5 12.0 4.4e-21 75.5 8.3 3.4 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.24 EGC30451.1 - 0.0014 18.8 3.2 0.0014 18.8 2.2 5.5 5 2 0 5 5 5 1 PH domain IQ PF00612.22 EGC30451.1 - 0.0015 17.9 2.0 0.0047 16.4 1.4 1.9 1 0 0 1 1 1 1 IQ calmodulin-binding motif Kdo PF06293.9 EGC30451.1 - 0.0033 16.5 0.1 0.01 14.9 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC30451.1 - 0.078 12.6 0.0 0.19 11.3 0.0 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family His_Phos_1 PF00300.17 EGC30452.1 - 2.1e-10 40.9 0.0 2.8e-10 40.4 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FNIP PF05725.7 EGC30453.1 - 2.7e-57 190.4 76.3 2.6e-15 56.1 0.6 10.0 7 3 2 10 10 10 9 FNIP Repeat FNIP PF05725.7 EGC30454.1 - 1.1e-65 217.3 61.1 2.5e-13 49.7 1.2 11.3 8 4 3 11 11 11 11 FNIP Repeat DUF1769 PF08588.5 EGC30454.1 - 0.011 15.6 0.7 11 6.0 0.1 5.2 5 1 1 6 6 6 0 Protein of unknown function (DUF1769) adh_short PF00106.20 EGC30455.1 - 0.0001 22.2 0.0 0.00017 21.5 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC30455.1 - 0.084 12.5 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 KR domain Coiled PF05710.7 EGC30456.1 - 3.9e-10 40.0 13.4 4.3e-10 39.9 9.3 1.0 1 0 0 1 1 1 1 Coiled coil Methyltransf_16 PF10294.4 EGC30456.1 - 0.083 12.3 0.1 0.09 12.2 0.1 1.1 1 0 0 1 1 1 0 Putative methyltransferase Coiled PF05710.7 EGC30457.1 - 2.7e-08 34.1 13.7 3.3e-08 33.8 9.5 1.0 1 0 0 1 1 1 1 Coiled coil Chlorosome_CsmC PF11098.3 EGC30457.1 - 0.22 11.2 5.0 0.3 10.7 3.3 1.3 1 1 0 1 1 1 0 Chlorosome envelope protein C DUF799 PF05643.6 EGC30457.1 - 0.27 10.5 1.8 0.29 10.4 1.3 1.2 1 0 0 1 1 1 0 Putative bacterial lipoprotein (DUF799) Endosulfine PF04667.12 EGC30458.1 - 4.8e-10 39.2 2.3 5.3e-10 39.1 1.6 1.1 1 0 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Pkinase PF00069.20 EGC30459.1 - 9e-68 228.2 0.0 1.2e-67 227.7 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30459.1 - 6.1e-53 179.5 0.0 8.7e-53 179.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC30459.1 - 2.4e-09 36.5 0.0 1.2e-07 31.0 0.0 2.2 2 0 0 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGC30459.1 - 0.033 13.5 1.3 1.6 8.0 0.1 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EGC30459.1 - 0.048 13.3 0.0 0.14 11.8 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC30459.1 - 0.077 12.0 0.1 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Tyr-DNA_phospho PF06087.7 EGC30460.1 - 1.2e-60 205.4 3.5 1.8e-60 204.8 2.5 1.2 1 0 0 1 1 1 1 Tyrosyl-DNA phosphodiesterase PLDc_2 PF13091.1 EGC30460.1 - 8.8e-05 22.2 0.2 0.02 14.6 0.1 2.4 2 0 0 2 2 2 2 PLD-like domain FAM163 PF15069.1 EGC30460.1 - 0.058 13.9 1.6 0.15 12.6 1.1 1.8 1 0 0 1 1 1 0 FAM163 family DUF3439 PF11921.3 EGC30460.1 - 0.12 12.1 6.7 0.28 10.9 4.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) hNIFK_binding PF12196.3 EGC30460.1 - 0.89 8.9 6.7 0.33 10.3 0.8 2.4 2 0 0 2 2 2 0 FHA Ki67 binding domain of hNIFK Mucin PF01456.12 EGC30460.1 - 2.1 8.1 21.4 3.6 7.3 14.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein SSP160 PF06933.6 EGC30460.1 - 9.1 4.1 13.7 12 3.6 9.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF718 PF05336.8 EGC30461.1 - 1.5e-26 92.2 1.9 1.8e-26 92.0 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF718) DUF1217 PF06748.7 EGC30461.1 - 0.14 12.2 0.1 0.24 11.4 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1217) TraB PF01963.12 EGC30462.1 - 2.6e-30 105.7 0.0 7.8e-23 81.2 0.0 2.4 2 0 0 2 2 2 2 TraB family DUF399 PF04187.8 EGC30462.1 - 0.14 11.5 0.2 0.52 9.7 0.0 2.0 3 0 0 3 3 3 0 Protein of unknown function, DUF399 EVC2_like PF12297.3 EGC30463.1 - 0.066 11.8 1.1 0.12 10.9 0.8 1.3 1 0 0 1 1 1 0 Ellis van Creveld protein 2 like protein Coiled PF05710.7 EGC30464.1 - 7e-06 26.4 17.4 9.2e-06 26.0 12.0 1.2 1 0 0 1 1 1 1 Coiled coil NIF PF03031.13 EGC30465.1 - 1.4e-21 76.7 1.5 3.2e-21 75.6 1.0 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase ubiquitin PF00240.18 EGC30465.1 - 1.8e-06 27.2 0.3 5.6e-06 25.6 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin family DUF3439 PF11921.3 EGC30466.1 - 0.077 12.7 9.5 0.19 11.5 6.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF971 PF06155.7 EGC30467.1 - 1.5e-25 89.4 0.0 2.5e-25 88.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF971) UCH PF00443.24 EGC30468.1 - 0.0078 15.3 3.4 0.014 14.5 2.3 1.6 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase LIM PF00412.17 EGC30469.1 - 4e-25 87.6 32.4 1.7e-08 34.4 2.4 3.3 3 0 0 3 3 3 3 LIM domain DUF3716 PF12511.3 EGC30469.1 - 0.001 18.5 14.7 0.2 11.3 0.5 3.4 3 0 0 3 3 3 3 Protein of unknown function (DUF3716) C1_1 PF00130.17 EGC30469.1 - 0.003 17.2 22.2 0.092 12.4 1.4 3.7 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prok-RING_1 PF14446.1 EGC30469.1 - 0.04 13.6 21.7 1 9.1 1.9 3.6 3 0 0 3 3 3 0 Prokaryotic RING finger family 1 VCX_VCY PF15231.1 EGC30469.1 - 0.16 12.4 23.2 6.9 7.0 16.1 2.6 1 1 0 1 1 1 0 Variable charge X/Y family TNFR_c6 PF00020.13 EGC30469.1 - 0.17 11.9 24.7 0.7 10.0 0.3 5.9 6 0 0 6 6 6 0 TNFR/NGFR cysteine-rich region Rieske PF00355.21 EGC30469.1 - 0.32 10.5 10.2 0.46 10.0 0.4 3.2 3 0 0 3 3 3 0 Rieske [2Fe-2S] domain CpXC PF14353.1 EGC30469.1 - 0.89 9.5 18.1 10 6.0 1.3 4.4 3 2 0 3 3 3 0 CpXC protein PHF5 PF03660.9 EGC30469.1 - 1.8 8.6 18.4 0.54 10.3 1.2 3.3 3 0 0 3 3 3 0 PHF5-like protein SIR2 PF02146.12 EGC30469.1 - 2.1 8.0 12.0 0.16 11.7 0.2 3.2 3 0 0 3 3 3 0 Sir2 family Nol1_Nop2_Fmu PF01189.12 EGC30470.1 - 2.4e-35 122.2 0.2 5e-35 121.2 0.0 1.5 2 0 0 2 2 2 1 NOL1/NOP2/sun family PUA PF01472.15 EGC30470.1 - 1.4e-05 24.6 0.3 4e-05 23.2 0.2 1.8 1 1 0 1 1 1 1 PUA domain FtsJ PF01728.14 EGC30470.1 - 5.2e-05 23.3 0.0 0.00012 22.1 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EGC30470.1 - 0.0019 18.7 0.0 0.004 17.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PcfK PF14058.1 EGC30470.1 - 0.0065 16.6 1.9 0.013 15.6 1.3 1.4 1 0 0 1 1 1 1 PcfK-like protein Methyltransf_24 PF13578.1 EGC30470.1 - 0.14 12.9 0.0 0.33 11.7 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain CemA PF03040.9 EGC30470.1 - 0.37 10.3 9.7 0.3 10.6 3.4 2.7 2 1 1 3 3 3 0 CemA family FNIP PF05725.7 EGC30471.1 - 5.3e-17 61.4 58.6 1.2e-08 34.7 2.2 11.7 7 2 5 12 12 12 9 FNIP Repeat Pex14_N PF04695.8 EGC30471.1 - 2.6 8.0 12.1 6 6.9 0.1 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DNase_II PF03265.10 EGC30473.1 - 1.2e-95 320.2 6.4 1.3e-95 320.0 4.4 1.0 1 0 0 1 1 1 1 Deoxyribonuclease II TPP_enzyme_N PF02776.13 EGC30474.1 - 3.7e-19 68.8 0.0 8.5e-18 64.4 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGC30474.1 - 1.8e-09 37.3 0.3 4.6e-08 32.7 0.0 3.4 3 1 0 3 3 3 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain CO_dh PF02552.11 EGC30474.1 - 0.0029 17.1 0.0 0.0061 16.1 0.0 1.5 1 0 0 1 1 1 1 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit TPP_enzyme_M PF00205.17 EGC30474.1 - 0.0069 16.1 0.0 0.06 13.0 0.0 2.2 1 1 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain DUF3875 PF12991.2 EGC30474.1 - 0.042 13.5 0.0 0.42 10.3 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3875) BBS2_Mid PF14783.1 EGC30475.1 - 0.0021 17.7 1.8 0.0042 16.8 0.0 2.4 3 1 1 4 4 4 1 Ciliary BBSome complex subunit 2, middle region WD40 PF00400.27 EGC30475.1 - 0.0067 16.2 0.0 0.014 15.2 0.0 1.6 1 0 0 1 1 1 1 WD domain, G-beta repeat Astro_capsid PF03115.9 EGC30475.1 - 0.023 13.0 2.0 0.03 12.6 1.4 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CENP-T PF15511.1 EGC30475.1 - 0.023 13.9 9.8 0.032 13.4 6.8 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EGC30475.1 - 0.23 9.4 13.3 0.38 8.7 9.2 1.3 1 0 0 1 1 1 0 CDC45-like protein I_LWEQ PF01608.12 EGC30476.1 - 2.7e-46 157.2 167.1 7.5e-39 133.0 10.4 16.9 8 4 8 17 17 17 10 I/LWEQ domain FERM_M PF00373.13 EGC30476.1 - 1.7e-23 83.1 0.1 1.7e-23 83.1 0.0 4.0 3 2 0 3 3 3 1 FERM central domain FERM_N PF09379.5 EGC30476.1 - 7.5e-12 45.1 1.0 5.3e-11 42.4 0.1 2.9 3 0 0 3 3 3 1 FERM N-terminal domain VBS PF08913.5 EGC30476.1 - 9.1e-05 22.7 1.5 9.1e-05 22.7 1.1 12.7 11 3 1 12 12 12 3 Vinculin Binding Site NAAA-beta PF15508.1 EGC30476.1 - 0.00012 22.3 0.3 0.22 11.8 0.0 5.3 4 0 0 4 4 4 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase ACBP PF00887.14 EGC30476.1 - 0.00055 19.5 0.5 0.0027 17.3 0.1 2.4 2 0 0 2 2 2 1 Acyl CoA binding protein Talin_middle PF09141.5 EGC30476.1 - 0.0041 16.8 6.1 0.0041 16.8 4.2 14.4 6 4 11 19 19 19 2 Talin, middle domain IRS PF02174.12 EGC30476.1 - 0.011 15.2 0.0 0.034 13.7 0.0 1.8 1 0 0 1 1 1 0 PTB domain (IRS-1 type) IPK PF03770.11 EGC30478.1 - 5.3e-54 182.8 0.1 1.2e-53 181.7 0.0 1.6 1 0 0 1 1 1 1 Inositol polyphosphate kinase IPP-2 PF04979.9 EGC30478.1 - 0.49 10.6 4.9 1.4 9.1 3.4 1.8 1 0 0 1 1 1 0 Protein phosphatase inhibitor 2 (IPP-2) Mucin PF01456.12 EGC30478.1 - 0.8 9.4 15.8 0.12 12.0 1.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein Autophagy_act_C PF03987.10 EGC30479.1 - 1.2e-15 57.4 3.5 1.4e-15 57.2 1.2 2.0 1 1 1 2 2 2 1 Autophagocytosis associated protein, active-site domain IBN_N PF03810.14 EGC30479.1 - 1.7 8.5 5.5 6 6.8 2.0 2.6 2 0 0 2 2 2 0 Importin-beta N-terminal domain Phos_pyr_kin PF08543.7 EGC30480.1 - 5e-17 61.9 0.0 8.1e-17 61.2 0.0 1.2 1 0 0 1 1 1 1 Phosphomethylpyrimidine kinase PfkB PF00294.19 EGC30480.1 - 2.6e-14 53.0 0.2 1.8e-12 47.0 0.1 2.8 1 1 0 1 1 1 1 pfkB family carbohydrate kinase RE_EcoO109I PF14511.1 EGC30480.1 - 0.051 12.9 0.5 0.17 11.2 0.1 1.9 2 0 0 2 2 2 0 Type II restriction endonuclease EcoO109I DUF1183 PF06682.7 EGC30481.1 - 0.0087 15.6 0.1 0.0087 15.6 0.1 2.5 2 1 1 3 3 3 1 Protein of unknown function (DUF1183) DUF4064 PF13273.1 EGC30481.1 - 0.024 14.7 2.8 0.64 10.1 0.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) MFS_Mycoplasma PF07672.8 EGC30481.1 - 0.026 13.7 0.2 0.026 13.7 0.1 2.0 2 0 0 2 2 2 0 Mycoplasma MFS transporter ODV-E18 PF10717.4 EGC30481.1 - 0.34 10.3 0.1 0.34 10.3 0.1 2.1 2 1 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Internalin_N PF12354.3 EGC30481.1 - 0.77 9.4 4.2 3.7 7.2 0.0 2.8 3 0 0 3 3 3 0 Bacterial adhesion/invasion protein N terminal Tetraspannin PF00335.15 EGC30481.1 - 1.4 8.1 10.9 0.53 9.5 2.2 2.3 2 1 0 2 2 2 0 Tetraspanin family DUF1980 PF09323.5 EGC30481.1 - 4.1 7.1 6.6 0.15 11.7 0.3 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) OAD_gamma PF04277.8 EGC30481.1 - 4.1 7.8 4.6 13 6.2 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF229 PF02995.12 EGC30482.1 - 2.7e-39 134.9 0.4 6e-39 133.8 0.3 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.18 EGC30482.1 - 0.0016 17.7 0.0 0.0025 17.0 0.0 1.4 1 1 0 1 1 1 1 Sulfatase RICTOR_N PF14664.1 EGC30482.1 - 0.062 11.8 0.2 0.094 11.2 0.1 1.1 1 0 0 1 1 1 0 Rapamycin-insensitive companion of mTOR, N-term 7TM_GPCR_Srw PF10324.4 EGC30483.1 - 0.13 11.3 0.1 0.13 11.3 0.1 2.1 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw YjgP_YjgQ PF03739.9 EGC30483.1 - 0.3 9.7 11.1 0.38 9.4 7.7 1.1 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family DUF1053 PF06327.9 EGC30483.1 - 2.5 8.4 8.5 0.96 9.8 1.6 2.3 2 0 0 2 2 2 0 Domain of Unknown Function (DUF1053) UPRTase PF14681.1 EGC30484.1 - 6.2e-66 221.5 0.0 8.7e-66 221.0 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase PRK PF00485.13 EGC30484.1 - 7.1e-55 185.5 0.1 1.1e-54 184.9 0.0 1.3 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_18 PF13238.1 EGC30484.1 - 2.5e-10 40.7 0.0 5.7e-10 39.5 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC30484.1 - 1.4e-09 38.7 0.1 3.1e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 AAA domain Pribosyltran PF00156.22 EGC30484.1 - 0.00014 21.5 0.0 0.00047 19.8 0.0 1.9 2 0 0 2 2 2 1 Phosphoribosyl transferase domain AAA_33 PF13671.1 EGC30484.1 - 0.00044 20.1 0.0 0.0012 18.7 0.0 1.8 1 1 0 1 1 1 1 AAA domain CoaE PF01121.15 EGC30484.1 - 0.0019 17.5 0.2 0.35 10.2 0.2 2.3 2 0 0 2 2 2 2 Dephospho-CoA kinase MobB PF03205.9 EGC30484.1 - 0.0052 16.5 0.1 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Spermine_synth PF01564.12 EGC30485.1 - 1.2e-90 302.7 0.0 1.9e-90 302.0 0.0 1.2 1 0 0 1 1 1 1 Spermine/spermidine synthase Methyltransf_18 PF12847.2 EGC30485.1 - 0.068 13.7 0.0 0.13 12.8 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain OST-HTH PF12872.2 EGC30486.1 - 0.054 13.3 0.5 0.071 12.9 0.4 1.3 1 0 0 1 1 1 0 OST-HTH/LOTUS domain PDDEXK_1 PF12705.2 EGC30487.1 - 3.7e-11 42.8 4.0 1e-09 38.1 0.5 2.3 2 0 0 2 2 2 2 PD-(D/E)XK nuclease superfamily BBS2_Mid PF14783.1 EGC30487.1 - 0.0016 18.1 0.7 0.023 14.4 0.0 2.8 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region Ribosomal_60s PF00428.14 EGC30487.1 - 0.019 15.3 1.0 0.019 15.3 0.7 3.5 3 0 0 3 3 3 0 60s Acidic ribosomal protein GNVR PF13807.1 EGC30487.1 - 0.63 9.8 7.3 6.7 6.5 0.2 3.5 2 1 2 4 4 4 0 G-rich domain on putative tyrosine kinase TIG PF01833.19 EGC30488.1 - 5.7e-16 58.2 46.9 3.1e-05 23.8 4.1 6.5 6 1 1 7 7 7 5 IPT/TIG domain EGF_2 PF07974.8 EGC30488.1 - 0.00048 20.2 12.0 0.0012 18.9 8.3 1.7 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC30488.1 - 0.028 14.3 7.4 0.066 13.1 5.1 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) WD40 PF00400.27 EGC30489.1 - 8.4e-13 47.6 2.9 0.0053 16.6 0.0 7.2 7 0 0 7 7 7 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC30489.1 - 0.024 14.3 0.0 0.53 10.0 0.0 3.0 3 2 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region LRR_9 PF14580.1 EGC30489.1 - 0.053 13.0 0.1 0.1 12.1 0.1 1.5 1 0 0 1 1 1 0 Leucine-rich repeat PQQ_3 PF13570.1 EGC30489.1 - 0.082 13.2 0.0 20 5.6 0.0 2.9 2 0 0 2 2 2 0 PQQ-like domain Gastrin PF00918.12 EGC30490.1 - 0.35 11.6 0.0 0.35 11.6 0.0 3.0 2 1 0 2 2 2 0 Gastrin/cholecystokinin family Zip PF02535.17 EGC30490.1 - 3.7 6.4 8.0 1.2 8.0 1.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter Methyltransf_11 PF08241.7 EGC30491.1 - 5.7e-16 58.7 0.0 8.7e-16 58.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC30491.1 - 2.6e-12 46.5 0.0 3.4e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC30491.1 - 4.2e-10 39.5 0.0 5.4e-10 39.2 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30491.1 - 2.2e-08 34.6 0.0 3.7e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC30491.1 - 4.7e-08 33.4 0.0 8.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC30491.1 - 6.1e-07 29.7 0.0 1.2e-06 28.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC30491.1 - 0.00019 20.6 0.0 0.00054 19.1 0.0 1.7 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family CMAS PF02353.15 EGC30491.1 - 0.00089 18.4 0.0 0.0014 17.8 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGC30491.1 - 0.0026 17.7 0.0 0.0092 16.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC30491.1 - 0.0052 16.4 0.0 0.01 15.4 0.0 1.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_4 PF02390.12 EGC30491.1 - 0.01 14.8 0.0 0.021 13.8 0.0 1.5 1 0 0 1 1 1 0 Putative methyltransferase RrnaAD PF00398.15 EGC30491.1 - 0.024 13.6 0.0 0.039 12.9 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase ANT PF03374.9 EGC30491.1 - 0.032 14.2 0.2 0.064 13.3 0.2 1.5 1 1 0 1 1 1 0 Phage antirepressor protein KilAC domain DREV PF05219.7 EGC30491.1 - 0.046 12.5 0.0 0.058 12.2 0.0 1.2 1 0 0 1 1 1 0 DREV methyltransferase Methyltransf_9 PF08003.6 EGC30491.1 - 0.06 12.0 0.0 0.098 11.3 0.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1698) Methyltransf_15 PF09445.5 EGC30491.1 - 0.064 12.8 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_32 PF13679.1 EGC30491.1 - 0.095 12.3 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain PrmA PF06325.8 EGC30491.1 - 0.12 11.4 0.0 0.17 10.9 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) An_peroxidase PF03098.10 EGC30492.1 - 2.7e-126 422.0 0.1 3.1e-126 421.8 0.1 1.0 1 0 0 1 1 1 1 Animal haem peroxidase DUF2207 PF09972.4 EGC30493.1 - 0.013 14.0 0.1 0.015 13.9 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF872 PF05915.7 EGC30493.1 - 0.04 13.7 2.1 0.084 12.7 0.5 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3923 PF13061.1 EGC30493.1 - 0.058 13.2 4.0 0.073 12.9 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3923) Imm10 PF15562.1 EGC30493.1 - 0.094 12.4 1.6 0.3 10.8 1.1 1.8 1 1 1 2 2 2 0 Immunity protein 10 DUF3671 PF12420.3 EGC30493.1 - 0.25 11.3 2.2 0.37 10.7 1.5 1.2 1 0 0 1 1 1 0 Protein of unknown function POX PF07526.6 EGC30494.1 - 0.26 11.5 5.0 0.32 11.2 3.4 1.2 1 0 0 1 1 1 0 Associated with HOX Gti1_Pac2 PF09729.4 EGC30494.1 - 1.3 8.9 7.9 1.5 8.6 5.5 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF3807 PF12720.2 EGC30494.1 - 1.9 8.6 9.6 2.2 8.4 6.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Tim54 PF11711.3 EGC30494.1 - 2.4 6.6 6.0 2.6 6.5 4.2 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 PH_4 PF15404.1 EGC30494.1 - 2.6 7.5 7.2 3.2 7.2 5.0 1.2 1 0 0 1 1 1 0 Pleckstrin homology domain GCD14 PF08704.5 EGC30494.1 - 4.4 6.7 7.1 4.6 6.6 4.9 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit XAP5 PF04921.9 EGC30494.1 - 5 6.6 13.9 6 6.3 9.7 1.1 1 0 0 1 1 1 0 XAP5, circadian clock regulator FimP PF09766.4 EGC30494.1 - 5.8 5.8 16.6 6.5 5.7 11.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Nop25 PF09805.4 EGC30494.1 - 8.3 6.4 9.7 11 6.0 6.7 1.3 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) NRDE-2 PF08424.5 EGC30494.1 - 8.6 5.1 13.5 9 5.0 9.4 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference Cyt-b5 PF00173.23 EGC30497.1 - 5.3e-23 80.6 0.2 6.8e-23 80.2 0.1 1.1 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-RING_2 PF13639.1 EGC30498.1 - 1.8e-08 34.0 12.0 4.5e-08 32.7 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC30498.1 - 2.6e-07 30.1 9.8 4.5e-07 29.4 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30498.1 - 4.8e-06 26.5 6.4 4.8e-06 26.5 4.5 2.9 3 0 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC30498.1 - 3.4e-05 23.7 14.0 8e-05 22.5 9.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC30498.1 - 3.7e-05 23.2 14.1 7.6e-05 22.2 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGC30498.1 - 0.016 14.7 12.1 0.029 13.9 8.4 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGC30498.1 - 0.019 14.6 12.4 0.019 14.6 8.6 2.3 2 1 1 3 3 3 0 zinc-RING finger domain Cu-oxidase_4 PF02578.10 EGC30498.1 - 0.085 11.9 0.9 0.14 11.1 0.7 1.3 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase zf-RING_6 PF14835.1 EGC30498.1 - 0.095 12.5 5.1 0.21 11.3 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC30498.1 - 0.12 12.2 10.6 0.74 9.7 7.3 2.4 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING OmpH PF03938.9 EGC30498.1 - 0.82 9.5 9.7 1.3 8.9 6.7 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) zf-Apc11 PF12861.2 EGC30498.1 - 1.3 8.8 8.3 0.042 13.6 1.0 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger GBP_C PF02841.9 EGC30498.1 - 3 6.9 18.9 4.3 6.4 13.1 1.1 1 0 0 1 1 1 0 Guanylate-binding protein, C-terminal domain CDC27 PF09507.5 EGC30498.1 - 4.6 6.3 23.1 4.3 6.4 15.4 1.3 1 1 0 1 1 1 0 DNA polymerase subunit Cdc27 AAA_23 PF13476.1 EGC30498.1 - 8.1 6.7 14.8 13 5.9 10.3 1.3 1 0 0 1 1 1 0 AAA domain OTU PF02338.14 EGC30499.1 - 1.2e-13 51.7 0.1 3.5e-13 50.2 0.1 1.8 1 0 0 1 1 1 1 OTU-like cysteine protease PAT1 PF09770.4 EGC30499.1 - 0.18 9.9 50.7 0.24 9.6 35.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGC30499.1 - 1.2 8.9 33.2 1.7 8.4 23.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PGAMP PF07644.6 EGC30500.1 - 0.44 10.3 2.5 1 9.1 0.1 2.4 3 0 0 3 3 3 0 Planctomycete PGAMP SAP PF02037.22 EGC30501.1 - 7.2e-05 22.1 0.0 0.00018 20.9 0.0 1.7 1 0 0 1 1 1 1 SAP domain Transferase PF02458.10 EGC30502.1 - 1.8e-13 49.7 0.0 2.6e-13 49.2 0.0 1.4 1 1 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC30502.1 - 0.0039 16.0 0.0 0.0058 15.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain Annexin PF00191.15 EGC30503.1 - 7.7e-86 281.9 9.7 2e-23 82.0 0.1 4.1 4 0 0 4 4 4 4 Annexin zf-RING_2 PF13639.1 EGC30504.1 - 3e-12 46.1 5.1 5.8e-12 45.2 3.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC30504.1 - 1.3e-08 34.6 6.3 3e-08 33.5 4.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC30504.1 - 2.6e-08 33.4 4.1 5.1e-08 32.4 2.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30504.1 - 4e-07 30.0 1.3 4e-07 30.0 0.9 2.4 3 0 0 3 3 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC30504.1 - 1.2e-06 28.0 6.9 4.1e-06 26.3 4.8 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC30504.1 - 2.1e-06 27.5 5.7 6.2e-06 25.9 4.0 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC30504.1 - 2.5e-06 27.1 6.2 5.7e-06 25.9 4.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Nse PF11789.3 EGC30504.1 - 8.7e-06 25.1 2.5 8.7e-06 25.1 1.7 2.5 3 0 0 3 3 3 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGC30504.1 - 9.8e-06 25.1 3.3 1.9e-05 24.2 1.2 2.5 1 1 0 1 1 1 1 RING-type zinc-finger WD40 PF00400.27 EGC30504.1 - 0.0022 17.7 2.8 0.0063 16.3 0.1 3.0 3 0 0 3 3 3 1 WD domain, G-beta repeat zf-Apc11 PF12861.2 EGC30504.1 - 0.24 11.2 3.2 0.21 11.4 0.9 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3439 PF11921.3 EGC30504.1 - 2.8 7.7 24.1 2.4 7.8 0.2 3.8 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) MOSC_N PF03476.11 EGC30506.1 - 1.6e-23 82.6 0.0 3.6e-23 81.5 0.0 1.6 2 0 0 2 2 2 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGC30506.1 - 8.2e-15 54.4 0.0 5.1e-14 51.8 0.0 2.2 2 1 0 2 2 2 1 MOSC domain p450 PF00067.17 EGC30507.1 - 2.5e-84 283.4 0.0 2.8e-84 283.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 AIRS PF00586.19 EGC30507.1 - 0.018 15.2 0.0 0.62 10.3 0.0 2.6 2 1 0 2 2 2 0 AIR synthase related protein, N-terminal domain CD36 PF01130.16 EGC30508.1 - 2.1e-40 138.4 0.1 2.5e-19 68.9 0.1 2.1 2 0 0 2 2 2 2 CD36 family PSDC PF12588.3 EGC30509.1 - 0.16 11.5 2.9 0.23 11.0 0.5 1.9 1 1 1 2 2 2 0 Phophatidylserine decarboxylase CemA PF03040.9 EGC30509.1 - 0.5 9.9 6.1 0.79 9.2 4.2 1.3 1 1 0 1 1 1 0 CemA family DUF1199 PF06712.6 EGC30509.1 - 1.9 8.3 5.2 0.99 9.2 0.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) FAM163 PF15069.1 EGC30510.1 - 0.00016 22.2 4.8 0.0003 21.3 2.9 1.8 1 1 1 2 2 2 1 FAM163 family Shisa PF13908.1 EGC30510.1 - 0.66 10.1 7.3 1.5 8.9 5.1 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Apc5 PF12862.2 EGC30511.1 - 2e-35 120.4 3.8 2.5e-34 116.9 0.8 3.5 3 1 0 3 3 3 1 Anaphase-promoting complex subunit 5 TPR_12 PF13424.1 EGC30511.1 - 2.1e-05 24.3 10.9 1.3 9.0 0.0 5.6 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC30511.1 - 0.0011 18.5 16.4 2 8.1 0.0 5.7 6 0 0 6 6 6 3 TPR repeat TPR_1 PF00515.23 EGC30511.1 - 0.0029 17.1 2.4 0.2 11.3 0.0 4.0 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC30511.1 - 0.012 15.3 13.7 11 6.1 0.0 6.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC30511.1 - 0.031 14.4 6.7 3.7 7.9 0.0 4.2 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EGC30512.1 - 6.1e-52 176.3 0.5 1.1e-51 175.5 0.3 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30512.1 - 1.9e-31 109.0 0.1 2.9e-31 108.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase ANTH PF07651.11 EGC30512.1 - 7.7e-12 44.4 0.3 8.8e-10 37.7 0.1 2.3 2 0 0 2 2 2 2 ANTH domain Kinase-like PF14531.1 EGC30512.1 - 0.00027 20.0 0.0 0.02 13.8 0.0 2.3 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGC30512.1 - 0.00072 19.3 0.0 0.64 9.7 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family HEPN PF05168.9 EGC30512.1 - 0.16 11.8 0.2 0.36 10.7 0.1 1.5 1 0 0 1 1 1 0 HEPN domain Ank PF00023.25 EGC30513.1 - 1.8e-30 103.2 1.0 6.5e-10 38.3 0.2 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EGC30513.1 - 2e-30 104.9 0.3 2.3e-22 79.1 0.1 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC30513.1 - 3.8e-26 88.5 1.7 1.1e-06 28.2 0.1 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EGC30513.1 - 4.9e-26 90.6 5.9 1.3e-09 38.3 0.0 3.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC30513.1 - 5.2e-24 83.7 6.6 1.1e-10 41.4 0.1 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) BTB PF00651.26 EGC30514.1 - 3e-17 62.6 0.3 2.3e-15 56.5 0.0 2.8 2 1 1 3 3 3 2 BTB/POZ domain TFIIB PF00382.14 EGC30515.1 - 0.018 14.8 0.0 0.12 12.1 0.0 2.3 3 0 0 3 3 3 0 Transcription factor TFIIB repeat A2M_comp PF07678.9 EGC30515.1 - 0.04 13.1 0.3 0.11 11.6 0.1 1.9 2 0 0 2 2 2 0 A-macroglobulin complement component Synaptobrevin PF00957.16 EGC30516.1 - 1.7e-29 101.2 7.6 1.9e-29 101.1 5.2 1.0 1 0 0 1 1 1 1 Synaptobrevin GP41 PF00517.12 EGC30516.1 - 0.0064 16.0 3.7 0.0081 15.7 2.6 1.1 1 0 0 1 1 1 1 Retroviral envelope protein DUF912 PF06024.7 EGC30516.1 - 0.011 15.7 1.5 0.013 15.4 1.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3675 PF12428.3 EGC30516.1 - 0.013 15.7 0.1 0.016 15.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) DUF812 PF05667.6 EGC30516.1 - 0.018 13.5 1.4 0.021 13.3 1.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF812) Rifin_STEVOR PF02009.11 EGC30516.1 - 0.028 14.0 2.1 0.03 13.9 1.5 1.1 1 0 0 1 1 1 0 Rifin/stevor family Hemagglutinin PF00509.13 EGC30516.1 - 0.042 11.9 3.1 0.053 11.6 2.2 1.0 1 0 0 1 1 1 0 Haemagglutinin Prominin PF05478.6 EGC30516.1 - 0.045 11.3 1.4 0.055 11.0 1.0 1.2 1 0 0 1 1 1 0 Prominin Fzo_mitofusin PF04799.8 EGC30516.1 - 0.046 13.1 2.2 0.064 12.6 1.5 1.3 1 0 0 1 1 1 0 fzo-like conserved region TraG_N PF07916.6 EGC30516.1 - 0.064 11.6 0.2 0.069 11.5 0.1 1.0 1 0 0 1 1 1 0 TraG-like protein, N-terminal region Laminin_II PF06009.7 EGC30516.1 - 0.17 11.6 2.3 0.2 11.4 1.6 1.1 1 0 0 1 1 1 0 Laminin Domain II Tmemb_cc2 PF10267.4 EGC30516.1 - 0.22 10.0 4.7 0.31 9.5 3.3 1.4 1 1 0 1 1 1 0 Predicted transmembrane and coiled-coil 2 protein Med11 PF10280.4 EGC30516.1 - 0.29 11.1 2.2 0.34 10.9 1.5 1.1 1 0 0 1 1 1 0 Mediator complex protein NPV_P10 PF05531.7 EGC30516.1 - 0.3 11.3 5.6 2.4 8.4 3.9 2.1 1 1 0 1 1 1 0 Nucleopolyhedrovirus P10 protein UPF0258 PF06789.7 EGC30516.1 - 0.51 10.3 5.5 0.38 10.7 2.9 1.4 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0258) BLOC1_2 PF10046.4 EGC30516.1 - 0.72 10.0 4.5 1 9.5 3.1 1.3 1 0 0 1 1 1 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF2570 PF10828.3 EGC30516.1 - 6.9 6.3 8.2 3.5 7.2 4.4 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2570) Med11 PF10280.4 EGC30517.1 - 0.00078 19.4 5.5 0.0022 18.0 3.8 1.6 1 1 0 1 1 1 1 Mediator complex protein F-box-like PF12937.2 EGC30518.1 - 1.3e-11 44.0 0.5 2.3e-11 43.2 0.4 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC30518.1 - 2.6e-05 23.7 0.6 5.2e-05 22.7 0.4 1.5 1 0 0 1 1 1 1 F-box domain DUF1355 PF07090.6 EGC30518.1 - 0.00045 19.6 0.0 0.00092 18.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1355) ThuA PF06283.6 EGC30518.1 - 0.0023 17.6 0.0 0.0043 16.7 0.0 1.3 1 0 0 1 1 1 1 Trehalose utilisation Elongin_A PF06881.6 EGC30518.1 - 0.042 14.2 1.7 0.06 13.7 0.0 2.0 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF1412 PF07203.6 EGC30518.1 - 0.52 10.2 4.7 0.56 10.1 1.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1412) DUF2135 PF09906.4 EGC30519.1 - 0.098 12.6 0.6 0.2 11.6 0.0 1.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2135) Fijivirus_P9-2 PF06837.6 EGC30519.1 - 0.19 10.8 5.3 0.26 10.3 3.7 1.1 1 0 0 1 1 1 0 Fijivirus P9-2 protein DUF1235 PF06822.7 EGC30520.1 - 0.04 12.8 0.2 0.044 12.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1235) DUF2666 PF10869.3 EGC30522.1 - 0.053 13.5 1.4 0.45 10.5 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2666) LAGLIDADG_1 PF00961.14 EGC30522.1 - 0.7 10.4 6.6 0.6 10.6 2.7 2.1 1 1 1 2 2 2 0 LAGLIDADG endonuclease MORN PF02493.15 EGC30523.1 - 0.025 14.2 0.2 0.025 14.2 0.1 2.8 3 0 0 3 3 3 0 MORN repeat MMR_HSR1 PF01926.18 EGC30524.1 - 2.3e-07 30.7 1.7 2.1e-06 27.6 1.2 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC30524.1 - 0.00012 21.2 0.4 0.00037 19.7 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGC30524.1 - 0.00017 22.0 21.7 0.002 18.5 14.7 2.6 1 1 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGC30524.1 - 0.00017 21.8 1.6 0.00046 20.4 0.0 2.4 2 1 0 2 2 2 1 ABC transporter MobB PF03205.9 EGC30524.1 - 0.00023 20.8 0.0 0.00063 19.4 0.0 1.7 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGC30524.1 - 0.003 17.4 0.0 0.0098 15.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain GTP_EFTU PF00009.22 EGC30524.1 - 0.0036 16.7 0.2 0.015 14.7 0.0 2.0 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGC30524.1 - 0.0086 15.9 4.4 0.3 10.9 0.0 3.3 2 2 1 3 3 3 1 Dynamin family NB-ARC PF00931.17 EGC30524.1 - 0.014 14.2 2.7 0.035 12.9 0.0 2.6 3 0 0 3 3 3 0 NB-ARC domain T2SE PF00437.15 EGC30524.1 - 0.017 14.0 0.1 0.038 12.8 0.1 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_22 PF13401.1 EGC30524.1 - 0.036 14.1 0.6 0.52 10.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_29 PF13555.1 EGC30524.1 - 0.04 13.4 0.0 0.09 12.3 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Torsin PF06309.6 EGC30524.1 - 0.046 13.6 0.3 0.19 11.6 0.0 2.0 2 0 0 2 2 2 0 Torsin AAA PF00004.24 EGC30524.1 - 0.067 13.4 0.3 0.34 11.1 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) SRP54 PF00448.17 EGC30524.1 - 0.086 12.2 0.2 0.4 10.1 0.1 2.2 1 1 0 1 1 1 0 SRP54-type protein, GTPase domain tRNA-synt_His PF13393.1 EGC30524.1 - 0.37 9.8 2.5 1 8.3 1.9 1.5 2 0 0 2 2 2 0 Histidyl-tRNA synthetase DUF87 PF01935.12 EGC30524.1 - 5.2 6.8 10.3 2 8.1 0.1 3.1 2 1 0 2 2 2 0 Domain of unknown function DUF87 HAUS-augmin3 PF14932.1 EGC30525.1 - 1.4 8.0 46.5 0.12 11.4 19.7 2.0 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 3 FUSC PF04632.7 EGC30525.1 - 3.1 6.1 7.2 3.3 6.0 5.0 1.0 1 0 0 1 1 1 0 Fusaric acid resistance protein family HSP70 PF00012.15 EGC30525.1 - 6.4 4.5 20.2 6.4 4.5 14.0 1.1 1 0 0 1 1 1 0 Hsp70 protein PLRV_ORF5 PF01690.12 EGC30525.1 - 7 5.6 17.4 9.1 5.3 12.1 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FNIP PF05725.7 EGC30529.1 - 6.3e-17 61.2 21.0 4.4e-09 36.1 1.8 5.8 4 2 0 4 4 4 3 FNIP Repeat GATA PF00320.22 EGC30530.1 - 0.026 13.8 1.0 0.026 13.8 0.7 1.9 2 0 0 2 2 2 0 GATA zinc finger Cript PF10235.4 EGC30530.1 - 0.028 14.7 5.1 2 8.8 0.9 2.3 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT Prim_Zn_Ribbon PF08273.7 EGC30530.1 - 0.045 13.8 1.0 0.16 12.0 0.1 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase DUF1489 PF07370.6 EGC30530.1 - 0.061 12.8 0.0 0.093 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1489) DZR PF12773.2 EGC30530.1 - 3.2 7.6 6.5 15 5.4 4.5 1.9 1 1 0 1 1 1 0 Double zinc ribbon DivIVA PF05103.8 EGC30531.1 - 1.3 9.0 45.3 0.079 13.0 14.2 4.6 4 1 1 5 5 5 0 DivIVA protein HrpB7 PF09486.5 EGC30531.1 - 5.4 6.9 11.9 12 5.7 8.2 1.5 1 0 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) Reo_sigmaC PF04582.7 EGC30531.1 - 6.8 5.7 7.1 26 3.8 1.9 2.4 1 1 1 2 2 2 0 Reovirus sigma C capsid protein GATA PF00320.22 EGC30532.1 - 3.7e-08 32.5 6.9 1.1e-07 31.1 4.8 1.8 1 1 0 1 1 1 1 GATA zinc finger AT_hook PF02178.14 EGC30532.1 - 0.052 13.2 7.5 0.1 12.3 5.2 1.5 1 0 0 1 1 1 0 AT hook motif DUF4508 PF14969.1 EGC30532.1 - 0.062 13.3 0.2 0.09 12.7 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) ELMO_CED12 PF04727.8 EGC30533.1 - 3.3e-39 134.1 0.1 8.9e-39 132.7 0.1 1.8 1 0 0 1 1 1 1 ELMO/CED-12 family Ank PF00023.25 EGC30533.1 - 2.9e-22 77.3 5.9 3.3e-06 26.6 0.0 5.2 4 0 0 4 4 4 4 Ankyrin repeat Ank_2 PF12796.2 EGC30533.1 - 1.1e-21 76.9 1.1 8.8e-14 51.6 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC30533.1 - 2.7e-18 64.2 4.9 3.4e-06 26.7 0.0 5.0 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EGC30533.1 - 1.8e-15 56.9 8.3 5.2e-09 36.3 0.4 5.2 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC30533.1 - 3.3e-12 46.2 25.0 3e-08 33.6 0.1 5.6 4 2 2 6 6 6 4 Ankyrin repeats (many copies) DUF3361 PF11841.3 EGC30533.1 - 2.4e-05 24.1 0.2 7.4e-05 22.5 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3361) DUF4042 PF13251.1 EGC30533.1 - 0.0041 16.6 0.0 0.0087 15.5 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4042) DUF2992 PF11208.3 EGC30533.1 - 0.013 15.3 0.4 2.3 8.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2992) Resolvase PF00239.16 EGC30535.1 - 3.7e-05 23.6 0.0 8.2e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Resolvase, N terminal domain SPT16 PF08644.6 EGC30535.1 - 0.16 11.8 4.7 3.1 7.6 0.2 2.3 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) DUF4548 PF15081.1 EGC30536.1 - 0.067 12.7 1.6 0.12 11.9 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4548) Erg28 PF03694.8 EGC30537.1 - 2.2e-18 66.2 3.4 2.6e-18 66.0 2.4 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF3169 PF11368.3 EGC30537.1 - 0.024 13.8 2.9 0.03 13.5 2.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) EamA PF00892.15 EGC30537.1 - 0.1 12.6 5.3 0.3 11.1 3.7 1.7 1 1 0 1 1 1 0 EamA-like transporter family MGAT2 PF05060.9 EGC30537.1 - 0.11 11.3 0.1 0.14 10.9 0.1 1.1 1 0 0 1 1 1 0 N-acetylglucosaminyltransferase II (MGAT2) DUF1133 PF06576.6 EGC30540.1 - 0.69 9.0 3.6 0.83 8.8 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1133) HTH_29 PF13551.1 EGC30544.1 - 1.2e-12 47.9 0.0 1.5e-12 47.6 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EGC30544.1 - 5e-11 41.8 0.1 1.5e-09 37.1 0.0 2.2 2 0 0 2 2 2 1 Homeodomain-like domain HTH_28 PF13518.1 EGC30544.1 - 3e-09 36.7 0.1 6.4e-08 32.4 0.0 2.2 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_38 PF13936.1 EGC30544.1 - 2.3e-07 30.2 2.7 1.7e-05 24.2 0.2 2.4 2 0 0 2 2 2 2 Helix-turn-helix domain HTH_32 PF13565.1 EGC30544.1 - 3.6e-06 27.6 0.1 5.7e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_7 PF02796.10 EGC30544.1 - 0.00013 21.7 1.0 0.03 14.1 0.0 2.8 3 0 0 3 3 3 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EGC30544.1 - 0.002 17.5 0.1 0.0037 16.7 0.0 1.4 1 0 0 1 1 1 1 Sigma-70, region 4 HTH_17 PF12728.2 EGC30544.1 - 0.003 17.7 0.3 0.019 15.2 0.0 2.1 2 0 0 2 2 2 1 Helix-turn-helix domain CENP-B_N PF04218.8 EGC30544.1 - 0.0068 15.7 0.4 0.064 12.6 0.1 2.3 2 0 0 2 2 2 1 CENP-B N-terminal DNA-binding domain HTH_Tnp_1 PF01527.15 EGC30544.1 - 0.029 14.3 0.0 0.046 13.6 0.0 1.3 1 0 0 1 1 1 0 Transposase HTH_Tnp_1_2 PF13022.1 EGC30544.1 - 0.047 13.4 0.0 0.076 12.8 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix of insertion element transposase HTH_Tnp_IS630 PF01710.11 EGC30544.1 - 0.051 13.2 0.5 0.14 11.8 0.3 1.8 1 1 0 1 1 1 0 Transposase HTH_3 PF01381.17 EGC30544.1 - 0.068 13.0 0.2 1.1 9.1 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix HTH_33 PF13592.1 EGC30544.1 - 0.12 11.9 0.2 0.26 10.8 0.0 1.7 2 0 0 2 2 2 0 Winged helix-turn helix HTH_Tnp_4 PF13613.1 EGC30544.1 - 0.13 11.7 0.0 0.61 9.6 0.0 1.9 2 0 0 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease Helicase_C PF00271.26 EGC30545.1 - 6.3e-13 48.3 0.0 1.1e-12 47.5 0.0 1.4 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FNIP PF05725.7 EGC30547.1 - 2.2e-32 110.7 29.0 1.5e-07 31.2 0.0 6.3 3 3 5 8 8 8 8 FNIP Repeat Alpha_kinase PF02816.13 EGC30548.1 - 2e-49 167.8 0.2 2e-49 167.8 0.1 2.8 2 1 0 2 2 2 1 Alpha-kinase family TIG PF01833.19 EGC30550.1 - 6.7e-14 51.6 36.1 2.2e-05 24.3 3.8 7.1 5 2 1 6 6 6 5 IPT/TIG domain SKG6 PF08693.5 EGC30550.1 - 0.038 13.2 0.0 0.084 12.2 0.0 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Ank_2 PF12796.2 EGC30551.1 - 0.00068 19.9 0.2 0.0019 18.4 0.2 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC30551.1 - 0.0015 18.9 0.0 0.0047 17.4 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC30551.1 - 0.0019 18.4 0.0 0.0077 16.4 0.0 2.1 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC30551.1 - 0.0026 17.8 0.0 0.014 15.5 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Ank PF00023.25 EGC30551.1 - 0.011 15.4 0.0 0.037 13.8 0.0 2.0 1 0 0 1 1 1 0 Ankyrin repeat Mucin PF01456.12 EGC30551.1 - 1.7 8.4 18.5 0.48 10.1 7.8 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein SPATIAL PF15256.1 EGC30551.1 - 2.7 8.0 12.6 0.47 10.4 2.0 2.6 2 0 0 2 2 2 0 SPATIAL DUF2894 PF11445.3 EGC30551.1 - 3.3 7.9 6.5 0.23 11.7 0.6 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2894) DUF3439 PF11921.3 EGC30551.1 - 4.5 7.0 13.6 0.18 11.5 2.8 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) B_lectin PF01453.19 EGC30552.1 - 2.6e-07 30.5 1.1 0.00057 19.7 0.0 2.6 3 0 0 3 3 3 2 D-mannose binding lectin Pkinase_Tyr PF07714.12 EGC30555.1 - 7.2e-46 156.3 0.0 9.1e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30555.1 - 8.3e-40 136.5 0.1 1.2e-39 136.0 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EGC30556.1 - 2.7e-24 84.9 60.9 3.3e-07 30.2 0.3 7.8 8 1 0 8 8 8 6 IPT/TIG domain UK PF02512.9 EGC30558.1 - 0.015 15.7 0.2 0.022 15.1 0.2 1.2 1 0 0 1 1 1 0 Virulence determinant GATA PF00320.22 EGC30558.1 - 0.074 12.4 2.6 0.21 10.9 1.8 1.8 1 1 0 1 1 1 0 GATA zinc finger RecR PF02132.10 EGC30558.1 - 1.2 8.6 6.8 6.1 6.3 4.7 2.0 1 1 0 1 1 1 0 RecR protein DUF3439 PF11921.3 EGC30559.1 - 0.058 13.1 2.0 0.091 12.5 1.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ABC2_membrane_3 PF12698.2 EGC30559.1 - 2.9 6.8 15.8 3.8 6.4 11.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein SAM_1 PF00536.25 EGC30560.1 - 9.5e-05 22.4 0.1 0.00016 21.8 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC30560.1 - 0.00059 19.6 0.0 0.00094 18.9 0.0 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mucin PF01456.12 EGC30560.1 - 0.1 12.3 19.3 0.16 11.7 13.4 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein MIP-T3 PF10243.4 EGC30560.1 - 7 4.9 28.3 8 4.8 19.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATP-synt_E PF05680.7 EGC30560.1 - 7 6.6 11.4 3.3 7.7 6.0 2.0 2 0 0 2 2 2 0 ATP synthase E chain LBP_BPI_CETP PF01273.20 EGC30561.1 - 5.4e-05 22.5 0.4 0.00011 21.5 0.3 1.5 1 0 0 1 1 1 1 LBP / BPI / CETP family, N-terminal domain Soyouz_module PF14313.1 EGC30561.1 - 0.00068 19.1 7.8 1.5 8.4 0.1 5.7 3 1 2 5 5 5 2 N-terminal region of Paramyxovirinae phosphoprotein (P) Clathrin-link PF09268.5 EGC30561.1 - 0.027 13.5 0.1 0.072 12.1 0.1 1.7 1 0 0 1 1 1 0 Clathrin, heavy-chain linker NAAA-beta PF15508.1 EGC30561.1 - 0.12 12.7 6.9 5.5 7.4 0.0 5.1 3 2 2 6 6 6 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase DUF4239 PF14023.1 EGC30561.1 - 0.19 11.0 0.7 1.4 8.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF4239) NGP1NT PF08153.7 EGC30562.1 - 1.6e-41 141.2 0.9 1.6e-41 141.2 0.6 2.3 2 0 0 2 2 2 1 NGP1NT (NUC091) domain MMR_HSR1 PF01926.18 EGC30562.1 - 2.4e-17 62.9 0.6 8.2e-14 51.5 0.0 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC30562.1 - 2.4e-05 23.6 0.0 0.0019 17.4 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B Arf PF00025.16 EGC30562.1 - 0.00062 19.0 0.2 0.37 10.0 0.0 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family DUF258 PF03193.11 EGC30562.1 - 0.003 16.7 0.0 0.0077 15.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGC30562.1 - 2.4 7.9 17.6 2 8.2 0.0 5.1 3 3 1 4 4 4 0 Dynamin family Ribosomal_L25p PF01386.14 EGC30563.1 - 5.8e-06 26.3 0.0 1e-05 25.5 0.0 1.4 1 0 0 1 1 1 1 Ribosomal L25p family DsrC PF04358.8 EGC30564.1 - 0.0082 16.3 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 1 DsrC like protein FAM163 PF15069.1 EGC30565.1 - 1 9.9 11.0 0.34 11.4 1.9 2.9 1 1 1 2 2 2 0 FAM163 family Beta-lactamase PF00144.19 EGC30566.1 - 1.5e-39 135.9 0.0 1.9e-39 135.6 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Myosin_head PF00063.16 EGC30567.1 - 5.9e-268 890.5 9.1 7.6e-268 890.1 6.3 1.1 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC30567.1 - 3.8e-46 156.9 8.8 7e-46 156.0 6.1 1.5 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 EGC30567.1 - 2.4e-07 29.7 3.9 0.00065 19.1 0.8 2.7 2 0 0 2 2 2 2 IQ calmodulin-binding motif Hpr_kinase_C PF07475.7 EGC30567.1 - 0.0035 16.6 1.1 0.36 10.1 0.1 2.7 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 EGC30567.1 - 0.0036 17.6 0.5 0.017 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC30567.1 - 0.0086 16.2 0.0 0.055 13.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC30567.1 - 0.031 13.3 0.0 0.066 12.3 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin AAA_17 PF13207.1 EGC30567.1 - 0.043 14.6 0.0 0.22 12.3 0.0 2.3 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC30567.1 - 0.071 13.0 0.0 0.21 11.5 0.0 1.7 2 0 0 2 2 2 0 AAA ATPase domain Histone PF00125.19 EGC30568.1 - 4.1e-11 42.8 0.0 5.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Myelin_PLP PF01275.14 EGC30568.1 - 0.099 11.9 0.0 0.11 11.8 0.0 1.1 1 0 0 1 1 1 0 Myelin proteolipid protein (PLP or lipophilin) polyprenyl_synt PF00348.12 EGC30569.1 - 9.6e-57 191.7 0.6 1.3e-56 191.3 0.4 1.2 1 0 0 1 1 1 1 Polyprenyl synthetase THF_DHG_CYH_C PF02882.14 EGC30570.1 - 3.2e-52 175.8 0.4 9e-51 171.1 0.1 2.2 2 0 0 2 2 2 2 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGC30570.1 - 1.6e-38 131.2 0.9 2.7e-38 130.6 0.6 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain TPR_8 PF13181.1 EGC30571.1 - 0.017 14.8 0.8 0.017 14.8 0.6 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat FAD_binding_3 PF01494.14 EGC30572.1 - 2.6e-24 85.9 1.4 7.6e-23 81.1 1.0 2.8 1 1 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGC30572.1 - 1.3e-06 27.5 0.0 0.018 13.9 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGC30572.1 - 9.8e-06 25.5 0.3 2.6e-05 24.1 0.2 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGC30572.1 - 0.0012 18.7 0.0 0.0026 17.6 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGC30572.1 - 0.0019 17.1 0.4 0.0031 16.4 0.3 1.3 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGC30572.1 - 0.0027 18.0 1.5 0.22 11.9 0.1 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Amino_oxidase PF01593.19 EGC30572.1 - 0.0042 16.2 0.0 0.092 11.7 0.0 2.1 2 0 0 2 2 2 1 Flavin containing amine oxidoreductase Med24_N PF11277.3 EGC30572.1 - 0.0061 14.1 0.0 0.009 13.5 0.0 1.2 1 0 0 1 1 1 1 Mediator complex subunit 24 N-terminal Pyr_redox_3 PF13738.1 EGC30572.1 - 0.017 15.1 0.1 0.053 13.5 0.1 1.8 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ADH_zinc_N_2 PF13602.1 EGC30574.1 - 0.0045 17.8 0.0 0.0075 17.1 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Resolvase PF00239.16 EGC30574.1 - 0.15 11.9 0.5 0.95 9.3 0.1 1.9 1 1 1 2 2 2 0 Resolvase, N terminal domain PAT1 PF09770.4 EGC30575.1 - 0.053 11.7 30.5 0.062 11.5 21.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TrkH PF02386.11 EGC30575.1 - 0.11 11.0 0.2 0.16 10.5 0.1 1.3 1 0 0 1 1 1 0 Cation transport protein AAA_23 PF13476.1 EGC30575.1 - 0.18 12.1 14.2 0.24 11.6 9.9 1.4 1 0 0 1 1 1 0 AAA domain P12 PF12669.2 EGC30575.1 - 0.25 11.5 7.2 0.42 10.8 5.0 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family APG6 PF04111.7 EGC30575.1 - 2.6 7.0 24.9 4 6.3 17.3 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 DUF1900 PF08954.6 EGC30576.1 - 0.094 12.2 0.0 0.11 11.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1900) DNase_II PF03265.10 EGC30577.1 - 4.8e-39 134.2 17.0 3.6e-33 114.9 7.2 3.2 2 1 0 2 2 2 2 Deoxyribonuclease II DUF2924 PF11149.3 EGC30577.1 - 0.07 13.1 0.0 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) SAP PF02037.22 EGC30578.1 - 5.4e-05 22.5 0.0 0.00018 20.9 0.0 1.9 2 0 0 2 2 2 1 SAP domain EGF_2 PF07974.8 EGC30579.1 - 0.25 11.5 9.9 0.58 10.3 6.9 1.6 1 0 0 1 1 1 0 EGF-like domain bZIP_1 PF00170.16 EGC30580.1 - 2.9e-13 49.5 8.2 1.1e-12 47.6 5.7 2.1 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGC30580.1 - 3.1e-11 42.9 7.4 3.1e-11 42.9 5.1 2.4 3 0 0 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGC30580.1 - 2.2e-05 24.6 5.7 2.2e-05 24.6 4.0 2.3 3 0 0 3 3 3 1 bZIP Maf transcription factor Striatin PF08232.7 EGC30580.1 - 0.025 14.9 8.5 1 9.6 0.1 2.3 2 0 0 2 2 2 0 Striatin family HCV_NS5a_C PF12941.2 EGC30580.1 - 0.13 11.8 0.9 0.19 11.2 0.6 1.3 1 0 0 1 1 1 0 HCV NS5a protein C-terminal region IncA PF04156.9 EGC30580.1 - 0.45 10.0 2.1 0.99 8.9 1.5 1.5 1 0 0 1 1 1 0 IncA protein PAT1 PF09770.4 EGC30580.1 - 1 7.5 22.7 1.3 7.1 15.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1777 PF08648.7 EGC30581.1 - 5.4e-14 52.3 106.5 5.1e-05 23.0 73.8 3.0 1 1 0 1 1 1 1 Protein of unknown function (DUF1777) MOR2-PAG1_N PF14222.1 EGC30581.1 - 0.23 10.1 5.3 0.38 9.3 3.7 1.3 1 0 0 1 1 1 0 Cell morphogenesis N-terminal NAD_binding_6 PF08030.7 EGC30582.1 - 1.5e-35 122.3 0.2 2.7e-35 121.6 0.1 1.4 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGC30582.1 - 6.1e-22 77.4 0.1 2.6e-21 75.4 0.0 2.1 2 0 0 2 2 2 1 FAD-binding domain Ferric_reduct PF01794.14 EGC30582.1 - 5.7e-19 68.4 1.7 5.7e-19 68.4 1.2 1.8 2 0 0 2 2 2 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGC30582.1 - 7.9e-06 25.9 0.0 2.5e-05 24.3 0.0 1.8 2 0 0 2 2 2 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGC30582.1 - 0.0036 17.8 0.0 0.014 15.9 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain LAP1C PF05609.7 EGC30582.1 - 0.095 11.3 0.0 0.16 10.5 0.0 1.3 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Nnf1 PF03980.9 EGC30583.1 - 1.8e-11 43.9 2.8 3.2e-11 43.1 1.9 1.4 1 0 0 1 1 1 1 Nnf1 RBFA PF02033.13 EGC30583.1 - 0.0073 16.3 0.2 0.014 15.4 0.2 1.5 1 0 0 1 1 1 1 Ribosome-binding factor A PV-1 PF06637.6 EGC30583.1 - 0.011 14.3 0.3 0.014 14.0 0.2 1.1 1 0 0 1 1 1 0 PV-1 protein (PLVAP) Syntaxin PF00804.20 EGC30583.1 - 0.041 14.0 8.4 0.83 9.8 5.6 2.4 1 1 0 1 1 1 0 Syntaxin Kri1 PF05178.7 EGC30583.1 - 0.087 13.1 1.3 0.18 12.0 0.9 1.6 1 0 0 1 1 1 0 KRI1-like family DASH_Dad1 PF08649.5 EGC30583.1 - 0.13 12.0 0.4 0.13 12.0 0.2 2.2 2 0 0 2 2 2 0 DASH complex subunit Dad1 SurA_N_3 PF13624.1 EGC30583.1 - 0.24 11.3 4.9 0.26 11.2 1.0 2.2 2 1 0 2 2 2 0 SurA N-terminal domain AAA_23 PF13476.1 EGC30583.1 - 0.8 9.9 12.7 0.99 9.6 8.8 1.2 1 0 0 1 1 1 0 AAA domain cwf21 PF08312.7 EGC30583.1 - 8.4 6.3 7.3 3.2 7.6 0.4 2.8 3 0 0 3 3 3 0 cwf21 domain cNMP_binding PF00027.24 EGC30584.1 - 8.9e-51 169.6 0.0 8.3e-25 86.4 0.0 2.2 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain 7TMR-HDED PF07697.6 EGC30584.1 - 0.0086 15.8 0.2 5.2 6.7 0.3 2.5 2 0 0 2 2 2 2 7TM-HD extracellular Actin PF00022.14 EGC30585.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC30585.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GATA PF00320.22 EGC30586.1 - 2.4e-08 33.1 1.4 9.8e-08 31.2 1.0 2.2 1 0 0 1 1 1 1 GATA zinc finger DUF3439 PF11921.3 EGC30586.1 - 0.18 11.5 8.0 0.093 12.4 3.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DEAD PF00270.24 EGC30587.1 - 4.5e-22 78.3 0.6 7.8e-21 74.3 0.0 3.2 3 1 1 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC30587.1 - 1.2e-21 76.3 0.7 3.3e-20 71.7 0.0 3.1 3 0 0 3 3 3 1 Helicase conserved C-terminal domain 2OG-FeII_Oxy_2 PF13532.1 EGC30588.1 - 0.0046 16.7 0.0 0.0072 16.1 0.0 1.3 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF4119 PF13494.1 EGC30588.1 - 1.2 9.1 5.5 4.9 7.1 3.8 2.1 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Bap31 PF05529.7 EGC30589.1 - 0.0018 17.7 3.5 0.0018 17.7 2.5 2.6 2 1 0 2 2 2 1 B-cell receptor-associated protein 31-like DUF3785 PF12653.2 EGC30589.1 - 1.2 8.9 8.2 0.069 13.0 1.1 2.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3785) DUF2340 PF10209.4 EGC30591.1 - 1.1e-41 141.8 1.5 1.2e-41 141.6 1.0 1.0 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2340) GABP-alpha PF11620.3 EGC30591.1 - 0.4 10.7 3.8 2.2 8.3 0.2 2.8 2 1 1 3 3 3 0 GA-binding protein alpha chain Band_7 PF01145.20 EGC30592.1 - 5e-33 114.4 4.4 6.9e-33 114.0 3.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0158 PF03682.8 EGC30592.1 - 0.002 17.7 0.6 0.009 15.6 0.3 2.0 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0158) Band_7_1 PF13421.1 EGC30592.1 - 0.058 12.9 0.4 0.087 12.3 0.3 1.3 1 0 0 1 1 1 0 SPFH domain-Band 7 family Pyr_redox_2 PF07992.9 EGC30594.1 - 2.8e-20 73.0 0.0 1.6e-19 70.5 0.0 2.6 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC30594.1 - 5.1e-17 62.0 1.0 1.4e-09 38.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGC30594.1 - 9.7e-08 31.4 0.0 0.0012 17.9 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain Pyr_redox_3 PF13738.1 EGC30594.1 - 5.7e-07 29.8 0.3 0.018 15.1 0.0 3.0 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC30594.1 - 2.8e-06 26.4 0.1 0.00049 19.1 0.0 2.4 2 0 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGC30594.1 - 4.9e-06 26.4 0.1 0.73 9.5 0.0 4.1 3 1 1 4 4 4 1 FAD-NAD(P)-binding NAD_binding_7 PF13241.1 EGC30594.1 - 7.6e-06 26.1 1.8 0.025 14.8 0.0 2.8 2 1 0 2 2 2 2 Putative NAD(P)-binding Trp_halogenase PF04820.9 EGC30594.1 - 5.6e-05 21.9 0.1 0.13 10.8 0.0 3.0 4 0 0 4 4 4 2 Tryptophan halogenase NAD_binding_8 PF13450.1 EGC30594.1 - 9.3e-05 22.3 0.1 0.004 17.1 0.0 2.4 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_DH PF01488.15 EGC30594.1 - 0.00017 21.7 0.9 0.012 15.6 0.0 2.6 1 1 1 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EGC30594.1 - 0.00031 19.7 0.7 0.11 11.4 0.0 3.6 4 0 0 4 4 4 1 FAD dependent oxidoreductase TrkA_N PF02254.13 EGC30594.1 - 0.00081 19.3 2.4 0.44 10.5 0.0 3.3 4 0 0 4 4 4 2 TrkA-N domain GIDA PF01134.17 EGC30594.1 - 0.00088 18.2 5.4 0.15 10.8 0.0 4.2 2 1 1 4 4 4 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGC30594.1 - 0.0028 16.6 0.0 8.5 5.1 0.0 3.3 3 1 1 4 4 4 0 Lycopene cyclase protein DUF4147 PF13660.1 EGC30594.1 - 0.006 15.7 0.9 6.9 5.6 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4147) Thi4 PF01946.12 EGC30594.1 - 0.0063 15.6 0.1 1.3 8.0 0.0 2.5 2 0 0 2 2 2 1 Thi4 family DUF2024 PF09630.5 EGC30594.1 - 0.0099 15.5 0.3 0.2 11.3 0.0 2.9 3 0 0 3 3 3 1 Domain of unknown function (DUF2024) Amino_oxidase PF01593.19 EGC30594.1 - 0.013 14.6 0.0 0.63 9.0 0.0 2.8 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Saccharop_dh PF03435.13 EGC30594.1 - 0.024 13.6 0.1 1.1 8.1 0.0 2.2 2 0 0 2 2 2 0 Saccharopine dehydrogenase Semialdhyde_dh PF01118.19 EGC30594.1 - 0.025 14.8 0.5 0.26 11.5 0.0 2.7 4 0 0 4 4 2 0 Semialdehyde dehydrogenase, NAD binding domain AlaDh_PNT_C PF01262.16 EGC30594.1 - 0.027 14.0 0.0 0.7 9.4 0.0 2.5 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain MTS_N PF08468.6 EGC30594.1 - 0.046 13.5 0.2 0.48 10.2 0.0 2.5 2 0 0 2 2 2 0 Methyltransferase small domain N-terminal HI0933_like PF03486.9 EGC30594.1 - 0.051 12.0 5.7 0.42 9.0 0.0 3.9 3 1 2 5 5 5 0 HI0933-like protein ThiF PF00899.16 EGC30594.1 - 0.061 13.1 2.9 7.8 6.3 0.0 3.6 3 1 0 3 3 3 0 ThiF family FAD_binding_2 PF00890.19 EGC30594.1 - 0.065 12.0 0.0 0.32 9.7 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain UDPG_MGDP_dh_N PF03721.9 EGC30594.1 - 0.12 11.7 3.0 0.23 10.8 0.0 2.6 2 1 0 3 3 3 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain LMBR1 PF04791.11 EGC30595.1 - 0.12 10.9 0.6 0.16 10.5 0.4 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein PBP1_TM PF14812.1 EGC30595.1 - 2.1 8.7 6.7 1.3 9.3 1.1 2.4 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal RhoGEF PF00621.15 EGC30596.1 - 3.5e-49 167.1 11.7 8.6e-49 165.8 6.9 2.6 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EGC30596.1 - 8.2e-06 25.9 0.2 2.5e-05 24.4 0.1 1.8 1 0 0 1 1 1 1 PH domain Ion_trans PF00520.26 EGC30596.1 - 0.0039 16.4 10.5 0.022 14.0 6.7 2.5 3 0 0 3 3 3 1 Ion transport protein Sod_Fe_N PF00081.17 EGC30596.1 - 0.68 10.2 11.9 0.3 11.3 0.2 4.1 3 0 0 3 3 3 0 Iron/manganese superoxide dismutases, alpha-hairpin domain Ribosomal_L18ae PF01775.12 EGC30597.1 - 2e-52 176.3 1.1 2.6e-52 175.9 0.8 1.1 1 0 0 1 1 1 1 Ribosomal L18ae/LX protein domain LIN37 PF15306.1 EGC30598.1 - 7e-05 22.8 3.2 7e-05 22.8 2.2 2.2 2 0 0 2 2 2 1 LIN37 DUF2977 PF11192.3 EGC30598.1 - 0.028 14.2 5.7 0.076 12.8 1.7 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2977) Metallophos PF00149.23 EGC30599.1 - 2.2e-07 30.4 2.1 4.1e-07 29.5 1.5 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase GHL5 PF14872.1 EGC30599.1 - 0.061 11.0 0.1 0.087 10.5 0.1 1.1 1 0 0 1 1 1 0 Hypothetical glycoside hydrolase 5 ABC2_membrane_3 PF12698.2 EGC30600.1 - 2.6e-51 174.6 71.9 2.9e-29 102.2 22.8 2.4 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 EGC30600.1 - 9.3e-50 168.4 0.3 6.2e-24 84.8 0.1 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC30600.1 - 8e-07 28.5 0.1 0.67 9.1 0.0 4.1 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC30600.1 - 0.00057 19.3 2.0 0.017 14.6 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGC30600.1 - 0.0014 18.5 0.1 0.53 10.2 0.0 3.4 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit SRP54 PF00448.17 EGC30600.1 - 0.0022 17.4 0.6 0.66 9.3 0.1 2.5 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EGC30600.1 - 0.012 15.9 10.0 0.1 12.9 0.1 3.7 3 1 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EGC30600.1 - 0.05 13.0 0.2 6.1 6.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC30600.1 - 0.095 11.8 0.7 1.9 7.6 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC30600.1 - 0.5 10.2 0.5 5.7 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain CTD_bind PF04818.8 EGC30602.1 - 0.042 14.0 0.2 0.086 13.0 0.1 1.5 1 1 1 2 2 2 0 RNA polymerase II-binding domain. NUMOD3 PF07460.6 EGC30602.1 - 0.054 13.3 0.1 0.082 12.8 0.1 1.4 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) DUF1016 PF06250.6 EGC30602.1 - 0.074 12.0 0.4 0.081 11.8 0.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1016) WD40 PF00400.27 EGC30603.1 - 1.2e-45 151.7 6.5 5.7e-10 38.6 0.0 6.6 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGC30603.1 - 1.1e-06 27.2 0.1 4e-05 22.0 0.0 2.4 2 1 1 3 3 3 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGC30603.1 - 3.6e-05 23.5 4.7 0.0063 16.2 0.4 3.8 3 1 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A UQ_con PF00179.21 EGC30604.1 - 8.8e-48 161.2 0.1 1.1e-47 161.0 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGC30604.1 - 6.6e-06 25.8 0.0 1e-05 25.2 0.0 1.3 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EGC30604.1 - 0.0003 20.6 0.1 0.00037 20.3 0.1 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGC30604.1 - 0.028 14.1 0.0 0.037 13.7 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B PI3Ka PF00613.15 EGC30605.1 - 4.3e-57 192.2 0.9 1.2e-56 190.7 0.6 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC30605.1 - 8.2e-54 182.5 0.0 8.2e-54 182.5 0.0 2.7 3 0 0 3 3 3 1 Phosphatidylinositol 3- and 4-kinase PI3K_rbd PF00794.13 EGC30605.1 - 3.2e-27 94.5 0.2 1.1e-25 89.6 0.0 2.9 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain PI3K_C2 PF00792.19 EGC30605.1 - 4e-26 91.4 0.1 1.6e-25 89.5 0.1 2.1 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 tRNA-synt_1c_C PF03950.13 EGC30607.1 - 0.046 13.3 1.3 0.12 12.0 0.6 1.7 1 1 0 1 1 1 0 tRNA synthetases class I (E and Q), anti-codon binding domain PHD PF00628.24 EGC30609.1 - 1.9e-05 24.2 20.4 0.00012 21.7 7.9 3.1 2 1 1 3 3 3 2 PHD-finger PHD_2 PF13831.1 EGC30609.1 - 0.0019 17.4 5.2 0.0019 17.4 3.6 2.7 2 1 1 3 3 3 1 PHD-finger zf-PHD-like PF15446.1 EGC30609.1 - 0.0042 16.3 2.2 0.0042 16.3 1.5 4.1 4 0 0 4 4 4 2 PHD/FYVE-zinc-finger like domain DUF282 PF03380.9 EGC30609.1 - 0.025 14.3 0.4 0.088 12.5 0.3 2.0 1 0 0 1 1 1 0 Caenorhabditis protein of unknown function, DUF282 DUF2180 PF09947.4 EGC30609.1 - 0.075 12.8 0.1 0.075 12.8 0.1 2.6 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2180) Prok-RING_1 PF14446.1 EGC30609.1 - 7.5 6.3 16.8 0.78 9.5 6.1 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 Motile_Sperm PF00635.21 EGC30610.1 - 2.5e-22 78.5 0.3 2.5e-22 78.5 0.2 2.0 2 1 0 2 2 2 1 MSP (Major sperm protein) domain DUF2624 PF11116.3 EGC30611.1 - 0.045 14.2 0.7 0.09 13.3 0.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) Cir_Bir_Yir PF06022.6 EGC30612.1 - 0.069 12.3 2.0 0.082 12.1 1.4 1.0 1 0 0 1 1 1 0 Plasmodium variant antigen protein Cir/Yir/Bir DUF2624 PF11116.3 EGC30612.1 - 0.095 13.2 0.6 0.12 12.8 0.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2624) SET PF00856.23 EGC30616.1 - 3.1e-16 60.1 0.0 1.1e-11 45.2 0.0 2.8 2 0 0 2 2 2 2 SET domain TPR_11 PF13414.1 EGC30616.1 - 3.8e-08 32.8 10.4 4.4e-07 29.4 2.7 2.9 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC30616.1 - 0.00092 18.9 3.8 0.015 15.1 0.3 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat DUF3385 PF11865.3 EGC30616.1 - 0.016 15.1 0.4 1.1 9.1 0.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3385) TPR_1 PF00515.23 EGC30616.1 - 0.026 14.1 10.0 0.03 13.9 0.6 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC30616.1 - 0.033 14.1 3.9 1.5 8.8 0.3 2.9 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF743 PF05332.6 EGC30618.1 - 0.093 12.6 4.2 0.12 12.3 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF743) Secretin_N_2 PF07655.8 EGC30618.1 - 0.14 12.5 14.2 0.25 11.7 9.8 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.7 EGC30619.1 - 8.8e-106 345.6 54.5 5.9e-16 58.1 0.7 8.9 3 1 1 9 9 9 8 FNIP Repeat Adap_comp_sub PF00928.16 EGC30620.1 - 1.2e-22 80.2 1.1 1.7e-22 79.7 0.8 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGC30620.1 - 2.2e-08 33.9 0.3 3.8e-08 33.1 0.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF3571 PF12095.3 EGC30620.1 - 0.1 12.8 1.3 16 5.8 0.1 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3571) DUF2356 PF10189.4 EGC30621.1 - 1.3e-96 322.1 0.2 2.2e-96 321.3 0.2 1.4 1 0 0 1 1 1 1 Conserved protein (DUF2356) WD40 PF00400.27 EGC30623.1 - 4.6e-34 115.0 8.5 3.9e-10 39.2 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Ras PF00071.17 EGC30624.1 - 3.2e-46 156.6 0.0 3.7e-46 156.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30624.1 - 2.3e-16 60.3 0.0 3.4e-16 59.8 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30624.1 - 1.2e-08 34.3 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC30624.1 - 0.014 15.3 0.0 0.025 14.5 0.0 1.3 1 1 0 1 1 1 0 50S ribosome-binding GTPase zf-C3HC4_3 PF13920.1 EGC30625.1 - 5.3e-13 48.4 12.0 8.8e-13 47.7 8.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC30625.1 - 2.3e-06 27.4 14.2 4.7e-06 26.5 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC30625.1 - 0.00028 20.6 11.8 0.00056 19.6 8.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-P11 PF03854.9 EGC30625.1 - 0.0081 15.6 9.4 0.0081 15.6 6.5 1.7 2 0 0 2 2 2 1 P-11 zinc finger zf-RING_5 PF14634.1 EGC30625.1 - 0.0084 15.8 11.4 0.018 14.7 7.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF3439 PF11921.3 EGC30625.1 - 0.55 10.0 15.0 0.049 13.3 6.6 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC30625.1 - 0.57 9.9 20.4 0.024 14.3 6.5 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein zf-RING_4 PF14570.1 EGC30625.1 - 1.1 8.9 8.7 2.2 7.9 6.0 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain SSP160 PF06933.6 EGC30625.1 - 2.9 5.7 22.6 0.008 14.2 6.4 2.1 2 0 0 2 2 2 0 Special lobe-specific silk protein SSP160 Ras PF00071.17 EGC30626.1 - 2.5e-59 199.2 0.0 3e-59 199.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30626.1 - 1.9e-21 76.7 0.0 2.7e-21 76.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30626.1 - 4.9e-18 64.9 0.0 6.4e-18 64.5 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC30626.1 - 9.9e-07 28.7 0.0 1.4e-06 28.2 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC30626.1 - 1.9e-06 27.4 0.0 1.3e-05 24.7 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC30626.1 - 7.5e-06 25.2 0.0 8.4e-06 25.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EGC30626.1 - 1.7e-05 24.5 0.0 0.0019 17.7 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EGC30626.1 - 0.0042 16.3 0.0 0.064 12.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EGC30626.1 - 0.0049 16.1 0.0 0.0075 15.4 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit PduV-EutP PF10662.4 EGC30626.1 - 0.015 14.7 0.0 0.2 11.1 0.0 2.5 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGC30626.1 - 0.13 12.2 0.2 0.33 10.9 0.1 1.7 1 1 0 1 1 1 0 AAA ATPase domain DNase_II PF03265.10 EGC30627.1 - 5e-37 127.6 12.6 1.5e-31 109.6 5.6 2.5 2 0 0 2 2 2 2 Deoxyribonuclease II DUF4322 PF14210.1 EGC30627.1 - 0.008 15.6 0.8 1.6 8.2 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF4322) PH PF00169.24 EGC30628.1 - 4.5e-17 62.1 4.7 4.5e-17 62.1 3.2 2.2 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC30628.1 - 1.8e-05 24.9 12.3 4.8e-05 23.5 0.4 3.1 3 1 1 4 4 4 2 Pleckstrin homology domain PH_3 PF14593.1 EGC30628.1 - 2.7e-05 24.0 2.6 5.8e-05 22.9 1.8 1.6 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGC30628.1 - 0.00012 22.0 0.4 0.00023 21.1 0.3 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain PH_9 PF15410.1 EGC30628.1 - 0.0034 17.5 0.4 0.015 15.4 0.3 2.2 1 1 0 1 1 1 1 Pleckstrin homology domain CENP-R PF06729.7 EGC30628.1 - 0.6 9.7 5.3 3.4 7.3 0.2 2.7 2 0 0 2 2 2 0 Kinetochore component, CENP-R DUF155 PF02582.9 EGC30629.1 - 1.1e-30 106.8 0.9 2e-30 105.9 0.6 1.5 1 0 0 1 1 1 1 Uncharacterised ACR, YagE family COG1723 Catalase PF00199.14 EGC30630.1 - 9.4e-190 630.2 0.6 1.1e-189 630.0 0.4 1.0 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGC30630.1 - 3.3e-20 71.7 0.0 9e-20 70.3 0.0 1.8 2 0 0 2 2 2 1 Catalase-related immune-responsive EF-hand_7 PF13499.1 EGC30631.1 - 1.2e-23 82.9 5.7 1.4e-12 47.5 0.4 2.6 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC30631.1 - 4.4e-22 75.6 3.8 1.9e-06 26.7 0.1 4.2 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EGC30631.1 - 1.2e-18 65.1 5.1 3.4e-05 23.3 0.0 4.5 4 2 1 5 5 5 3 EF-hand domain EF-hand_5 PF13202.1 EGC30631.1 - 1.3e-18 65.3 8.9 9.7e-07 27.8 0.5 3.7 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EGC30631.1 - 1e-13 50.6 3.1 0.00066 19.2 0.1 3.6 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_4 PF12763.2 EGC30631.1 - 9.7e-06 25.2 1.0 0.082 12.6 0.1 3.1 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGC30631.1 - 6.2e-05 23.0 2.9 0.88 9.6 0.1 3.6 2 2 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGC30631.1 - 0.016 15.0 0.0 0.09 12.7 0.0 2.3 3 1 0 3 3 3 0 EF-hand domain EF-hand_10 PF14788.1 EGC30631.1 - 0.27 10.9 2.8 2 8.1 0.4 2.8 3 0 0 3 3 3 0 EF hand HCaRG PF07258.9 EGC30631.1 - 0.41 10.1 5.5 0.27 10.7 0.3 2.5 3 1 0 3 3 3 0 HCaRG protein Dockerin_1 PF00404.13 EGC30631.1 - 8.1 6.3 10.0 4.5 7.1 0.2 3.5 3 0 0 3 3 3 0 Dockerin type I repeat TMF_TATA_bd PF12325.3 EGC30632.1 - 5e-31 106.9 8.5 5e-31 106.9 5.9 7.8 3 1 6 10 10 10 1 TATA element modulatory factor 1 TATA binding TMF_DNA_bd PF12329.3 EGC30632.1 - 7.7e-10 38.4 13.3 7.7e-10 38.4 9.2 10.1 5 2 6 11 11 11 3 TATA element modulatory factor 1 DNA binding CENP-F_leu_zip PF10473.4 EGC30632.1 - 0.00019 21.3 12.9 0.00019 21.3 9.0 8.8 4 1 3 7 7 7 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Reo_sigmaC PF04582.7 EGC30632.1 - 0.00076 18.7 3.4 0.00076 18.7 2.4 4.8 4 1 2 6 6 6 2 Reovirus sigma C capsid protein DivIC PF04977.10 EGC30632.1 - 0.0092 15.4 1.7 0.0092 15.4 1.2 10.7 5 4 7 12 12 12 2 Septum formation initiator IKKbetaNEMObind PF12179.3 EGC30632.1 - 1 9.1 7.7 0.76 9.6 0.3 4.4 3 1 1 4 4 4 0 I-kappa-kinase-beta NEMO binding domain AAA_11 PF13086.1 EGC30633.1 - 2.6e-70 236.6 0.0 2.6e-70 236.6 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_12 PF13087.1 EGC30633.1 - 1.3e-59 200.9 1.3 2.2e-58 196.9 0.0 2.8 3 0 0 3 3 3 1 AAA domain AAA_19 PF13245.1 EGC30633.1 - 2.4e-12 46.4 0.0 8.9e-08 31.7 0.0 3.1 3 0 0 3 3 3 2 Part of AAA domain AAA_30 PF13604.1 EGC30633.1 - 7.6e-07 28.9 5.0 0.0087 15.6 0.0 3.3 4 1 0 4 4 4 2 AAA domain Viral_helicase1 PF01443.13 EGC30633.1 - 1.9e-06 27.6 0.7 0.0095 15.4 0.0 3.7 4 0 0 4 4 3 2 Viral (Superfamily 1) RNA helicase PhoH PF02562.11 EGC30633.1 - 0.0034 16.6 0.2 0.13 11.5 0.0 2.4 2 0 0 2 2 2 1 PhoH-like protein AAA_22 PF13401.1 EGC30633.1 - 0.01 15.9 0.1 0.84 9.7 0.0 3.2 2 1 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGC30633.1 - 0.017 14.5 0.1 0.057 12.8 0.1 1.9 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGC30633.1 - 0.034 13.5 0.0 0.13 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain Mg_chelatase PF01078.16 EGC30633.1 - 0.04 13.0 0.0 0.1 11.7 0.0 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_23 PF13476.1 EGC30633.1 - 0.065 13.5 0.1 0.065 13.5 0.0 3.4 3 0 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EGC30633.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ResIII PF04851.10 EGC30633.1 - 0.29 10.9 12.9 1 9.1 0.0 3.7 3 0 0 3 3 3 0 Type III restriction enzyme, res subunit NARP1 PF12569.3 EGC30633.1 - 2.5 6.7 18.8 4.4 5.9 13.1 1.3 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 DNA_pol_A_exo1 PF01612.15 EGC30635.1 - 1.9e-07 30.7 0.1 3.6e-07 29.8 0.1 1.4 1 0 0 1 1 1 1 3'-5' exonuclease FAM222A PF15258.1 EGC30635.1 - 0.045 12.9 0.1 0.083 12.0 0.0 1.4 1 0 0 1 1 1 0 Protein family of FAM222A PARP PF00644.15 EGC30636.1 - 2.6e-14 53.1 11.3 2.6e-14 53.1 7.8 2.9 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain UIM PF02809.15 EGC30636.1 - 2.3e-05 23.5 14.9 0.0081 15.6 0.3 3.5 3 0 0 3 3 3 3 Ubiquitin interaction motif UBX PF00789.15 EGC30637.1 - 2.8e-12 46.5 0.4 7.2e-12 45.2 0.0 1.9 2 0 0 2 2 2 1 UBX domain Helicase_C PF00271.26 EGC30638.1 - 5.5e-09 35.7 0.0 1.7e-08 34.1 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4233 PF14017.1 EGC30638.1 - 0.035 14.0 2.1 0.13 12.2 1.4 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF4233) Isochorismatase PF00857.15 EGC30639.1 - 2.8e-33 115.2 0.0 3.1e-33 115.1 0.0 1.0 1 0 0 1 1 1 1 Isochorismatase family Endonuclease_NS PF01223.18 EGC30640.1 - 6.9e-42 143.4 2.7 1.1e-41 142.7 1.9 1.3 1 0 0 1 1 1 1 DNA/RNA non-specific endonuclease STN PF07660.9 EGC30645.1 - 0.068 12.7 0.5 0.42 10.2 0.0 2.6 2 0 0 2 2 2 0 Secretin and TonB N terminus short domain LRR_4 PF12799.2 EGC30645.1 - 0.31 10.7 11.6 1.3 8.7 0.5 3.9 2 1 2 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30645.1 - 0.4 10.4 11.7 3.6 7.3 2.6 3.4 3 1 0 3 3 3 0 Leucine rich repeat I_LWEQ PF01608.12 EGC30646.1 - 1.9 8.4 12.2 0.21 11.5 4.6 2.2 1 1 1 2 2 2 0 I/LWEQ domain OmpH PF03938.9 EGC30646.1 - 3.9 7.3 20.6 8.7 6.2 14.3 1.6 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) BRCT PF00533.21 EGC30647.1 - 1.3e-09 38.0 5.1 0.00039 20.5 0.1 3.7 3 0 0 3 3 3 2 BRCA1 C Terminus (BRCT) domain FAD_binding_1 PF00667.15 EGC30648.1 - 9.3e-12 44.8 0.1 1.1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain Peptidase_S24 PF00717.18 EGC30648.1 - 0.03 13.9 0.2 0.3 10.7 0.0 2.4 2 1 1 3 3 3 0 Peptidase S24-like Ribosomal_S13 PF00416.17 EGC30648.1 - 0.071 13.5 0.8 0.087 13.2 0.1 1.4 2 0 0 2 2 2 0 Ribosomal protein S13/S18 Cadherin_C PF01049.12 EGC30648.1 - 0.077 13.0 0.1 0.089 12.8 0.1 1.2 1 0 0 1 1 1 0 Cadherin cytoplasmic region Cnd3 PF12719.2 EGC30648.1 - 0.12 11.3 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Nuclear condensing complex subunits, C-term domain GpcrRhopsn4 PF10192.4 EGC30649.1 - 2.8e-40 138.1 36.1 2.8e-40 138.1 25.0 2.1 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Glyco_hydro_47 PF01532.15 EGC30650.1 - 9e-133 443.2 0.2 1.3e-132 442.7 0.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 EGC30650.1 - 0.073 12.0 0.0 8.3 5.3 0.0 3.4 4 0 0 4 4 4 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) CBM49 PF09478.5 EGC30651.1 - 1.4e-20 73.1 4.2 2.6e-20 72.2 2.9 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 RhoGEF PF00621.15 EGC30652.1 - 4.1e-39 134.3 2.8 4.1e-39 134.3 1.9 2.6 2 0 0 2 2 2 1 RhoGEF domain PH_10 PF15411.1 EGC30652.1 - 0.0016 18.5 0.0 0.0016 18.5 0.0 3.9 4 0 0 4 4 4 1 Pleckstrin homology domain IQ PF00612.22 EGC30652.1 - 0.013 15.0 0.9 0.026 14.1 0.7 1.5 1 0 0 1 1 1 0 IQ calmodulin-binding motif Nop25 PF09805.4 EGC30652.1 - 0.86 9.6 16.5 2.5 8.1 1.7 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Cna_B PF05738.8 EGC30654.1 - 4.8e-115 375.4 81.5 5.6e-13 48.4 0.1 17.1 16 0 0 16 16 16 16 Cna protein B-type domain CarboxypepD_reg PF13620.1 EGC30654.1 - 4.4e-85 279.8 43.3 1.5e-08 34.6 0.2 16.8 16 0 0 16 16 16 16 Carboxypeptidase regulatory-like domain fn3_3 PF14686.1 EGC30654.1 - 8.5e-15 54.6 38.0 0.00077 19.5 0.1 13.2 14 0 0 14 14 14 5 Polysaccharide lyase family 4, domain II MG1 PF11974.3 EGC30654.1 - 7.3e-11 42.4 0.3 0.31 11.6 0.0 9.1 9 0 0 9 9 9 1 Alpha-2-macroglobulin MG1 domain DUF2012 PF09430.5 EGC30654.1 - 1.3e-09 37.9 17.9 0.04 13.7 0.0 10.0 13 0 0 13 13 13 2 Protein of unknown function (DUF2012) phage_tail_N PF08400.5 EGC30654.1 - 1.7e-09 37.5 11.2 4.7 6.9 0.0 11.3 12 0 0 12 12 12 2 Prophage tail fibre N-terminal DUF4198 PF10670.4 EGC30654.1 - 0.00011 22.3 9.0 0.27 11.2 0.1 7.4 9 0 0 9 9 9 1 Domain of unknown function (DUF4198) Chorein_N PF12624.2 EGC30655.1 - 6e-29 99.9 1.3 1.6e-27 95.3 0.3 3.8 2 0 0 2 2 2 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC30655.1 - 0.0084 16.2 0.0 0.028 14.5 0.0 1.9 1 0 0 1 1 1 1 ATG C terminal domain DUF3040 PF11239.3 EGC30655.1 - 8.9 6.4 3.1 15 5.7 0.6 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3040) PIP5K PF01504.13 EGC30657.1 - 1.3e-58 198.0 6.6 1.3e-58 198.0 4.6 1.8 2 0 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase PAT1 PF09770.4 EGC30657.1 - 1.1 7.3 46.0 0.037 12.2 27.7 1.5 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 DUF4557 PF15101.1 EGC30657.1 - 5.7 6.7 28.4 0.57 9.9 11.1 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4557) DUF2360 PF10152.4 EGC30657.1 - 8.3 6.6 27.1 14 5.9 14.6 2.5 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein (DUF2360) SLT PF01464.15 EGC30658.1 - 3.1e-08 33.1 0.0 5e-08 32.4 0.0 1.4 1 1 0 1 1 1 1 Transglycosylase SLT domain Transglycosylas PF06737.9 EGC30658.1 - 0.00013 22.2 2.8 0.0004 20.6 2.0 1.9 1 0 0 1 1 1 1 Transglycosylase-like domain Lys PF00062.15 EGC30658.1 - 0.00041 20.3 6.9 0.0016 18.3 4.7 1.9 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family RAP1 PF07218.6 EGC30658.1 - 4.9 5.1 17.7 5.8 4.8 12.3 1.2 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) FNIP PF05725.7 EGC30659.1 - 2.7e-153 497.7 73.5 5.1e-16 58.3 0.2 11.5 4 3 9 15 15 15 15 FNIP Repeat DUF1769 PF08588.5 EGC30659.1 - 0.00059 19.7 40.3 6.3 6.8 0.2 12.6 2 2 14 16 16 16 6 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC30660.1 - 1.9e-108 354.1 55.5 4.6e-15 55.2 0.5 7.6 2 2 8 11 11 11 10 FNIP Repeat Terminase_1 PF03354.10 EGC30660.1 - 0.03 12.7 0.3 0.041 12.3 0.2 1.1 1 0 0 1 1 1 0 Phage Terminase FNIP PF05725.7 EGC30661.1 - 1.6e-59 197.5 27.9 1.1e-13 50.8 0.2 6.2 4 1 1 6 6 6 6 FNIP Repeat FNIP PF05725.7 EGC30662.1 - 8.3e-15 54.4 4.6 4.5e-07 29.7 0.1 2.5 2 0 0 2 2 2 2 FNIP Repeat zf-RVT PF13966.1 EGC30663.1 - 0.056 13.7 0.0 0.1 12.9 0.0 1.4 1 0 0 1 1 1 0 zinc-binding in reverse transcriptase FNIP PF05725.7 EGC30664.1 - 3.7e-165 535.7 68.7 2e-16 59.6 0.1 13.9 11 2 2 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.8 EGC30664.1 - 2.8e-05 24.0 0.0 11 6.0 0.0 7.0 4 2 2 7 7 7 2 Phage minor tail protein FNIP PF05725.7 EGC30665.1 - 6e-208 672.6 113.6 2e-16 59.6 1.3 16.4 7 2 9 19 19 19 19 FNIP Repeat Phage_min_tail PF05939.8 EGC30665.1 - 0.00012 22.0 0.0 37 4.3 0.0 7.7 6 3 4 10 10 10 1 Phage minor tail protein HSP20 PF00011.16 EGC30666.1 - 8.3e-14 51.2 1.2 4.4e-07 29.6 0.1 2.3 1 1 0 2 2 2 2 Hsp20/alpha crystallin family NUFIP1 PF10453.4 EGC30666.1 - 0.041 13.3 2.9 0.43 10.1 0.1 2.7 2 0 0 2 2 2 0 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) Transferase PF02458.10 EGC30667.1 - 8.7e-12 44.2 0.1 1.2e-11 43.7 0.1 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC30667.1 - 0.034 13.0 0.0 0.091 11.5 0.0 1.7 2 0 0 2 2 2 0 Condensation domain Transferase PF02458.10 EGC30668.1 - 6.1e-13 47.9 0.0 9.3e-13 47.3 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC30668.1 - 0.0041 16.0 0.0 0.0057 15.5 0.0 1.3 1 0 0 1 1 1 1 Condensation domain DUF4300 PF14133.1 EGC30669.1 - 0.023 13.9 0.1 0.03 13.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4300) DUF3290 PF11694.3 EGC30669.1 - 0.08 12.6 0.1 0.08 12.6 0.1 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF3290) Epiglycanin_C PF14654.1 EGC30669.1 - 0.088 12.8 0.9 0.18 11.8 0.4 1.6 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region NB PF04159.8 EGC30669.1 - 1.5 8.5 5.3 0.52 10.0 0.2 2.3 2 1 0 2 2 2 0 NB glycoprotein SR-25 PF10500.4 EGC30670.1 - 0.91 8.9 8.2 1.4 8.3 5.7 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein PA26 PF04636.8 EGC30670.1 - 1.8 7.1 8.7 2.5 6.7 6.1 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF2457 PF10446.4 EGC30670.1 - 2.9 6.5 12.3 4.3 5.9 8.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) zf-RING_2 PF13639.1 EGC30671.1 - 5e-09 35.8 3.0 5e-09 35.8 2.1 4.1 4 1 0 4 4 4 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC30671.1 - 9.3e-08 31.6 1.7 9.3e-08 31.6 1.2 4.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC30671.1 - 2.1e-06 27.6 2.8 2.1e-06 27.6 1.9 4.6 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30671.1 - 8.4e-06 25.4 1.6 8.4e-06 25.4 1.1 5.1 4 1 0 4 4 4 1 zinc-RING finger domain FANCL_C PF11793.3 EGC30671.1 - 0.00023 21.0 2.6 0.00023 21.0 1.8 2.7 3 1 0 3 3 3 1 FANCL C-terminal domain zf-C3HC4 PF00097.20 EGC30671.1 - 0.00042 19.9 1.0 0.00042 19.9 0.7 4.6 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30671.1 - 0.0024 17.9 3.4 0.0024 17.9 2.4 4.2 2 1 0 2 2 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC30671.1 - 0.0027 17.3 0.1 0.0027 17.3 0.1 3.8 4 0 0 4 4 4 1 RING-type zinc-finger PEP_mutase PF13714.1 EGC30672.1 - 4.3e-59 199.6 0.1 4.9e-59 199.4 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate phosphomutase ICL PF00463.16 EGC30672.1 - 4.6e-17 61.4 0.1 6.9e-17 60.8 0.1 1.2 1 0 0 1 1 1 1 Isocitrate lyase family NanE PF04131.9 EGC30672.1 - 0.0099 14.8 0.1 0.036 13.0 0.1 1.9 1 1 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase FTCD PF02971.9 EGC30672.1 - 0.12 12.0 0.0 4.4 6.9 0.0 2.3 2 0 0 2 2 2 0 Formiminotransferase domain RCR PF12273.3 EGC30673.1 - 0.013 16.0 0.1 0.034 14.6 0.1 1.6 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red SHR3_chaperone PF08229.6 EGC30673.1 - 0.019 13.9 0.5 0.047 12.6 0.3 1.6 1 0 0 1 1 1 0 ER membrane protein SH3 EGF_2 PF07974.8 EGC30673.1 - 0.89 9.7 8.7 2.2 8.5 6.0 1.7 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 EGC30674.1 - 0.00023 21.1 0.2 0.00023 21.1 0.1 2.8 3 0 0 3 3 3 1 IPT/TIG domain FNIP PF05725.7 EGC30675.1 - 1.5e-20 72.8 58.4 4.4e-05 23.3 2.3 10.8 6 3 5 11 11 11 11 FNIP Repeat zf-A20 PF01754.11 EGC30676.1 - 1.1e-10 40.8 7.1 1.1e-10 40.8 4.9 2.6 3 0 0 3 3 3 1 A20-like zinc finger zf-AN1 PF01428.11 EGC30676.1 - 2.3e-07 30.5 8.4 2.3e-07 30.5 5.8 1.9 2 0 0 2 2 2 1 AN1-like Zinc finger Pyr_redox_2 PF07992.9 EGC30677.1 - 4.5e-22 78.9 0.1 9.8e-22 77.8 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase AIF_C PF14721.1 EGC30677.1 - 4e-18 65.9 2.9 1.7e-10 41.2 0.0 3.2 2 1 1 3 3 3 2 Apoptosis-inducing factor, mitochondrion-associated, C-term NAD_binding_9 PF13454.1 EGC30677.1 - 2.8e-09 36.9 0.0 0.0012 18.6 0.0 3.5 2 1 1 3 3 3 3 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGC30677.1 - 7.2e-07 29.5 0.1 6.9e-06 26.3 0.0 2.4 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC30677.1 - 3e-06 27.4 0.0 0.58 10.1 0.0 3.2 3 0 0 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGC30677.1 - 0.00012 21.1 1.2 0.00053 19.0 0.0 2.4 2 1 0 3 3 3 1 FAD dependent oxidoreductase NAD_binding_7 PF13241.1 EGC30677.1 - 0.00062 19.9 0.0 0.012 15.8 0.0 2.7 3 0 0 3 3 3 1 Putative NAD(P)-binding Amino_oxidase PF01593.19 EGC30677.1 - 0.0015 17.6 0.0 0.0025 16.9 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HI0933_like PF03486.9 EGC30677.1 - 0.0038 15.7 0.0 0.11 10.9 0.0 2.6 3 0 0 3 3 3 1 HI0933-like protein Reductase_C PF14759.1 EGC30677.1 - 0.11 12.8 0.0 0.38 11.0 0.0 2.0 1 0 0 1 1 1 0 Reductase C-terminal WD40 PF00400.27 EGC30678.1 - 3.1e-66 217.0 16.2 1.4e-12 46.9 0.3 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIID_90kDa PF04494.10 EGC30678.1 - 9.5e-46 155.4 4.4 2e-45 154.3 3.1 1.5 1 0 0 1 1 1 1 WD40 associated region in TFIID subunit LisH PF08513.6 EGC30678.1 - 0.00086 18.9 0.1 0.0025 17.5 0.1 1.9 1 0 0 1 1 1 1 LisH Cytochrom_D1 PF02239.11 EGC30678.1 - 0.024 12.9 0.0 0.044 12.0 0.0 1.4 1 0 0 1 1 1 0 Cytochrome D1 heme domain Endotoxin_N PF03945.9 EGC30679.1 - 1.5e-13 50.6 1.4 1.5e-13 50.6 1.0 2.1 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Glyco_hydro_42M PF08532.5 EGC30681.1 - 4.8e-05 22.6 0.0 0.00097 18.3 0.0 2.3 2 0 0 2 2 2 1 Beta-galactosidase trimerisation domain zf-CCHC PF00098.18 EGC30681.1 - 0.003 17.4 18.4 0.011 15.6 0.3 3.2 3 0 0 3 3 3 2 Zinc knuckle DUF4159 PF13709.1 EGC30681.1 - 0.016 14.3 0.0 0.11 11.5 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4159) zf-CCHC_4 PF14392.1 EGC30681.1 - 0.03 13.9 7.4 1.6 8.4 0.4 3.0 2 0 0 2 2 2 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGC30681.1 - 1 9.1 9.4 6.1e+02 0.2 6.5 2.8 1 1 0 1 1 1 0 Zinc knuckle tRNA_edit PF04073.10 EGC30682.1 - 1.2e-06 28.4 0.0 2.3e-06 27.4 0.0 1.4 1 1 0 1 1 1 1 Aminoacyl-tRNA editing domain rve PF00665.21 EGC30682.1 - 0.0042 17.1 0.1 0.025 14.6 0.0 2.1 3 0 0 3 3 3 1 Integrase core domain Vps26 PF03643.10 EGC30686.1 - 7.5e-44 149.5 1.4 9.7e-44 149.1 0.9 1.1 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 26 Arrestin_N PF00339.24 EGC30686.1 - 6.9e-11 42.1 0.2 8.8e-10 38.5 0.0 2.4 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain CS PF04969.11 EGC30686.1 - 0.07 13.6 0.8 0.21 12.1 0.5 1.8 1 0 0 1 1 1 0 CS domain LeuA_dimer PF08502.5 EGC30686.1 - 0.082 12.6 0.0 0.16 11.8 0.0 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain Act-Frag_cataly PF09192.5 EGC30687.1 - 3.9e-71 239.2 13.2 3.9e-71 239.2 9.2 1.7 2 0 0 2 2 2 1 Actin-fragmin kinase, catalytic Phage_Gp111 PF07410.6 EGC30688.1 - 0.044 13.9 2.4 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 Streptococcus thermophilus bacteriophage Gp111 protein TPR_11 PF13414.1 EGC30689.1 - 0.12 12.0 0.2 0.12 12.0 0.1 2.2 3 0 0 3 3 3 0 TPR repeat TPR_12 PF13424.1 EGC30689.1 - 0.15 12.0 1.3 0.25 11.3 0.1 1.9 3 0 0 3 3 3 0 Tetratricopeptide repeat ATG2_CAD PF13329.1 EGC30689.1 - 0.32 10.5 4.5 0.57 9.7 3.1 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif TPR_2 PF07719.12 EGC30689.1 - 0.38 10.7 7.4 5.9 7.0 0.1 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat RabGAP-TBC PF00566.13 EGC30690.1 - 3.7e-47 160.5 0.1 5.4e-47 160.0 0.1 1.2 1 0 0 1 1 1 1 Rab-GTPase-TBC domain p450 PF00067.17 EGC30691.1 - 6.6e-91 305.1 0.5 7.8e-91 304.8 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_3 PF13358.1 EGC30692.1 - 4.2e-09 36.2 0.1 4.8e-09 36.1 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-B_box PF00643.19 EGC30693.1 - 1.3e-05 24.9 4.9 1.3e-05 24.9 3.4 1.9 2 0 0 2 2 2 1 B-box zinc finger PRP1_N PF06424.7 EGC30693.1 - 0.1 12.9 1.7 0.16 12.2 1.2 1.4 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal DUF2935 PF11155.3 EGC30693.1 - 0.13 12.3 3.7 0.1 12.7 1.5 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) FlxA PF14282.1 EGC30693.1 - 0.23 11.3 1.9 0.42 10.5 1.3 1.4 1 0 0 1 1 1 0 FlxA-like protein Eapp_C PF10238.4 EGC30693.1 - 0.28 11.0 10.4 0.52 10.1 7.2 1.6 1 1 0 1 1 1 0 E2F-associated phosphoprotein DUF4014 PF13198.1 EGC30693.1 - 2.4 8.6 4.9 4.3 7.8 1.5 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4014) FNIP PF05725.7 EGC30694.1 - 2.7e-07 30.4 4.7 1.1e-05 25.2 0.3 7.0 7 1 0 7 7 7 3 FNIP Repeat zf-B_box PF00643.19 EGC30694.1 - 1.1e-06 28.4 4.2 1.1e-06 28.4 2.9 2.1 2 0 0 2 2 2 1 B-box zinc finger YchF-GTPase_C PF06071.8 EGC30695.1 - 3.3e-41 138.9 1.0 8.6e-41 137.6 0.7 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF933) MMR_HSR1 PF01926.18 EGC30695.1 - 1.7e-16 60.1 0.0 4.6e-16 58.8 0.0 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC30695.1 - 2.9e-06 26.6 0.0 9.9e-06 24.9 0.0 1.8 2 0 0 2 2 2 1 Ferrous iron transport protein B ArgK PF03308.11 EGC30695.1 - 0.062 12.0 0.0 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 ArgK protein DUF4134 PF13572.1 EGC30696.1 - 0.051 13.6 3.2 1.1 9.4 2.2 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4134) DUF4190 PF13828.1 EGC30696.1 - 7.2 6.2 7.0 9.9 5.8 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) RWD PF05773.17 EGC30697.1 - 7.9e-11 41.8 0.1 2.3e-10 40.3 0.1 1.7 1 0 0 1 1 1 1 RWD domain GST_N PF02798.15 EGC30698.1 - 8.1e-13 48.3 0.0 2.4e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC30698.1 - 2.4e-10 40.4 0.0 4.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC30698.1 - 3.2e-10 39.8 0.3 9.4e-10 38.3 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC30698.1 - 6.8e-05 22.6 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC30698.1 - 0.00059 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC30698.1 - 0.0018 18.7 0.0 0.0026 18.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phage_hub_GP28 PF11110.3 EGC30698.1 - 0.089 12.4 0.3 0.16 11.6 0.2 1.4 1 1 0 1 1 1 0 Baseplate hub distal subunit GST_N PF02798.15 EGC30699.1 - 8.1e-13 48.3 0.0 2.4e-12 46.8 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC30699.1 - 2.4e-10 40.4 0.0 4.7e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC30699.1 - 3.2e-10 39.8 0.3 9.4e-10 38.3 0.2 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC30699.1 - 6.8e-05 22.6 0.0 0.00012 21.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC30699.1 - 0.00059 19.7 0.0 0.0014 18.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC30699.1 - 0.0018 18.7 0.0 0.0026 18.1 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Phage_hub_GP28 PF11110.3 EGC30699.1 - 0.089 12.4 0.3 0.16 11.6 0.2 1.4 1 1 0 1 1 1 0 Baseplate hub distal subunit DUF2798 PF11391.3 EGC30700.1 - 0.0015 18.2 2.5 0.014 15.1 0.3 3.0 3 0 0 3 3 3 1 Protein of unknown function (DUF2798) Chorion_2 PF03964.10 EGC30700.1 - 9.7 6.8 7.8 3.2 8.3 1.9 2.3 2 0 0 2 2 2 0 Chorion family 2 DUF3430 PF11912.3 EGC30701.1 - 1.3e-14 54.5 30.8 1.6e-14 54.2 21.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC30701.1 - 2.2 8.3 12.3 1.2 9.2 2.2 3.4 1 1 3 4 4 4 0 Protein of unknown function (DUF3586) DUF3430 PF11912.3 EGC30702.1 - 1e-15 58.1 33.1 1.3e-15 57.7 23.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC30702.1 - 0.57 10.2 11.3 0.49 10.4 1.0 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3586) DUF1835 PF08874.5 EGC30703.1 - 1.8 8.4 6.8 0.36 10.7 1.8 2.2 2 1 0 2 2 2 0 Domain of unknown function (DUF1835) GerA PF03323.8 EGC30703.1 - 5.7 4.9 5.8 2.7 6.0 2.1 1.8 1 1 0 1 1 1 0 Bacillus/Clostridium GerA spore germination protein SH3_1 PF00018.23 EGC30704.1 - 2.1e-14 52.6 0.2 4.1e-14 51.6 0.2 1.5 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC30704.1 - 1.2e-13 50.3 0.2 2.5e-13 49.3 0.2 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC30704.1 - 3.1e-11 42.5 0.1 5.7e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain DivIC PF04977.10 EGC30704.1 - 0.012 15.0 5.4 0.012 15.0 3.7 3.6 5 1 1 6 6 6 0 Septum formation initiator AAA_23 PF13476.1 EGC30704.1 - 5.6 7.2 35.9 1.5e+04 -11.0 24.9 2.4 1 1 0 1 1 1 0 AAA domain ICMT PF04140.9 EGC30705.1 - 8.8e-28 96.3 0.1 1.7e-27 95.4 0.1 1.4 1 0 0 1 1 1 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family PEMT PF04191.8 EGC30705.1 - 5.7e-12 45.6 1.8 5.7e-12 45.6 1.2 2.3 2 1 1 3 3 3 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGC30705.1 - 0.0052 16.1 3.5 0.007 15.6 2.4 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) NnrU PF07298.6 EGC30705.1 - 0.0052 16.1 1.7 0.0093 15.3 1.2 1.4 1 0 0 1 1 1 1 NnrU protein MerC PF03203.9 EGC30705.1 - 0.07 13.4 3.0 0.079 13.3 0.6 1.9 1 1 0 2 2 2 0 MerC mercury resistance protein DAP_epimerase PF01678.14 EGC30707.1 - 1.5e-34 118.5 0.5 5.7e-16 58.5 0.0 2.6 2 1 0 2 2 2 2 Diaminopimelate epimerase MSA-2c PF12238.3 EGC30708.1 - 0.014 15.0 2.0 0.026 14.2 1.4 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Flavodoxin_4 PF12682.2 EGC30708.1 - 0.041 13.2 0.0 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Flavodoxin ADK PF00406.17 EGC30708.1 - 0.12 12.2 0.0 0.15 11.9 0.0 1.2 1 0 0 1 1 1 0 Adenylate kinase APP_N PF02177.11 EGC30708.1 - 0.15 11.9 1.1 0.26 11.2 0.8 1.5 1 1 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Phage_gp53 PF11246.3 EGC30708.1 - 0.8 9.1 10.0 0.036 13.5 1.2 2.0 2 0 0 2 2 2 0 Base plate wedge protein 53 MS_channel PF00924.13 EGC30708.1 - 3.8 6.8 11.8 13 5.0 4.3 2.1 1 1 1 2 2 2 0 Mechanosensitive ion channel CDC45 PF02724.9 EGC30709.1 - 0.0013 16.8 20.4 0.0017 16.5 14.1 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.8 EGC30709.1 - 0.0031 17.1 27.4 0.0048 16.5 19.0 1.2 1 0 0 1 1 1 1 YL1 nuclear protein Utp14 PF04615.8 EGC30709.1 - 0.16 10.0 32.3 0.23 9.5 22.4 1.1 1 0 0 1 1 1 0 Utp14 protein MIP-T3 PF10243.4 EGC30709.1 - 0.82 8.0 33.6 1.3 7.4 23.3 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Mem_trans PF03547.13 EGC30709.1 - 1.4 7.1 8.9 2.1 6.5 6.2 1.3 1 0 0 1 1 1 0 Membrane transport protein DDHD PF02862.12 EGC30709.1 - 3.7 7.2 15.4 8.7 6.0 10.6 1.6 1 0 0 1 1 1 0 DDHD domain DUF2201_N PF13203.1 EGC30709.1 - 5.5 6.0 13.1 8.6 5.4 9.1 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain LMBR1 PF04791.11 EGC30709.1 - 5.8 5.3 13.3 9.3 4.7 9.2 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein ETRAMP PF09716.5 EGC30710.1 - 1.5 8.8 4.0 0.8 9.7 0.1 2.3 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF4419 PF14388.1 EGC30711.1 - 6.5e-91 304.6 0.6 6.5e-91 304.6 0.4 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) Rad33 PF08730.5 EGC30712.1 - 0.024 14.1 0.0 0.04 13.3 0.0 1.3 1 0 0 1 1 1 0 Rad33 Y1_Tnp PF01797.11 EGC30712.1 - 0.068 13.0 0.2 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Transposase IS200 like E1-E2_ATPase PF00122.15 EGC30713.1 - 1.5e-50 171.3 2.6 2.7e-50 170.5 1.8 1.4 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC30713.1 - 6.5e-49 167.2 0.0 1e-48 166.5 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGC30713.1 - 8.2e-26 89.9 0.8 8.2e-10 38.6 0.2 3.6 3 0 0 3 3 3 3 Heavy-metal-associated domain HAD PF12710.2 EGC30713.1 - 7.4e-17 62.1 0.0 2.6e-16 60.3 0.0 2.0 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGC30713.1 - 1.1e-05 25.2 0.2 0.033 13.7 0.0 3.0 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase p450 PF00067.17 EGC30714.1 - 3.2e-95 319.3 0.0 3.5e-95 319.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 PP2C PF00481.16 EGC30715.1 - 4.2e-40 137.7 0.0 7.2e-40 136.9 0.0 1.3 1 0 0 1 1 1 1 Protein phosphatase 2C CENP-Q PF13094.1 EGC30715.1 - 0.084 12.8 2.8 0.17 11.8 1.9 1.5 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit LRR_8 PF13855.1 EGC30716.1 - 6.3e-25 86.7 46.4 5.7e-11 42.0 1.7 6.3 2 1 6 8 8 8 7 Leucine rich repeat Epimerase PF01370.16 EGC30716.1 - 1.6e-21 76.8 0.1 2.8e-21 76.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family LRR_4 PF12799.2 EGC30716.1 - 5.9e-20 70.4 59.0 5.6e-10 38.6 1.6 8.3 5 1 3 9 9 9 6 Leucine Rich repeats (2 copies) Polysacc_synt_2 PF02719.10 EGC30716.1 - 1.6e-14 53.5 0.0 3.6e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein LRR_1 PF00560.28 EGC30716.1 - 9.2e-11 40.2 54.1 0.0087 15.9 0.1 11.4 12 1 1 13 13 13 7 Leucine Rich Repeat 3Beta_HSD PF01073.14 EGC30716.1 - 5.4e-10 38.4 1.3 9.8e-10 37.5 0.9 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGC30716.1 - 9.2e-09 34.5 0.0 1.6e-08 33.7 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain LRR_7 PF13504.1 EGC30716.1 - 2.5e-08 32.7 30.0 2.3 8.8 0.1 10.5 10 0 0 10 10 10 2 Leucine rich repeat NAD_binding_4 PF07993.7 EGC30716.1 - 9.6e-08 31.2 0.1 1.6e-07 30.4 0.1 1.3 1 0 0 1 1 1 1 Male sterility protein LRR_6 PF13516.1 EGC30716.1 - 0.03 14.3 46.8 5.8 7.3 0.4 10.4 9 2 1 10 10 10 0 Leucine Rich repeat Pkinase_Tyr PF07714.12 EGC30717.1 - 1e-51 175.4 0.0 1.8e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30717.1 - 1.7e-47 161.7 0.0 3.6e-47 160.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain LRR_4 PF12799.2 EGC30717.1 - 1.1e-21 75.9 34.5 2.8e-07 30.0 0.5 7.0 5 2 2 7 7 7 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30717.1 - 1.1e-17 63.4 25.1 4.1e-06 26.4 2.0 5.4 2 1 4 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EGC30717.1 - 6e-15 52.9 28.8 0.004 16.9 0.2 10.6 8 1 1 9 9 9 6 Leucine Rich Repeat Miro PF08477.8 EGC30717.1 - 1.7e-13 51.0 1.5 4.2e-08 33.6 0.0 3.8 4 0 0 4 4 4 2 Miro-like protein Ras PF00071.17 EGC30717.1 - 1.8e-11 43.7 6.2 4.6e-09 35.8 0.0 3.1 4 0 0 4 4 4 2 Ras family PH PF00169.24 EGC30717.1 - 3.7e-06 27.0 0.3 1.4e-05 25.2 0.2 2.1 1 0 0 1 1 1 1 PH domain LRR_7 PF13504.1 EGC30717.1 - 5.7e-05 22.6 19.9 6.3 7.4 0.1 8.5 7 0 0 7 7 7 2 Leucine rich repeat PH_11 PF15413.1 EGC30717.1 - 0.0067 16.6 4.3 0.11 12.7 3.0 3.0 1 1 0 1 1 1 1 Pleckstrin homology domain LRR_6 PF13516.1 EGC30717.1 - 0.11 12.6 30.1 1.2 9.4 0.4 8.8 8 0 0 8 8 8 0 Leucine Rich repeat LAGLIDADG_1 PF00961.14 EGC30718.1 - 0.0044 17.5 2.5 0.0061 17.1 1.4 1.5 1 1 0 1 1 1 1 LAGLIDADG endonuclease DUF3979 PF13141.1 EGC30718.1 - 0.055 13.3 0.0 0.093 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3979) Phage_GP20 PF06810.6 EGC30719.1 - 0.012 15.0 5.0 0.016 14.6 3.5 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF4509 PF14970.1 EGC30719.1 - 0.014 15.1 0.3 0.017 14.8 0.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) Herpes_BLRF2 PF05812.7 EGC30719.1 - 0.2 11.4 4.2 0.37 10.6 2.9 1.4 1 0 0 1 1 1 0 Herpesvirus BLRF2 protein Laminin_II PF06009.7 EGC30719.1 - 0.31 10.8 2.9 0.43 10.3 2.0 1.1 1 0 0 1 1 1 0 Laminin Domain II CAF-1_p150 PF11600.3 EGC30719.1 - 8.2 5.7 9.1 0.82 9.0 3.5 1.4 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-LSD1 PF06943.7 EGC30720.1 - 0.053 13.1 2.2 2.6 7.7 0.0 2.3 2 0 0 2 2 2 0 LSD1 zinc finger zf-RING_2 PF13639.1 EGC30721.1 - 5.5e-08 32.5 11.7 8.6e-08 31.8 8.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC30721.1 - 2.4e-05 23.8 14.1 4.5e-05 23.0 9.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30721.1 - 3.7e-05 23.7 6.7 8e-05 22.6 4.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC30721.1 - 6e-05 22.6 9.8 9e-05 22.0 6.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC30721.1 - 0.00018 21.4 13.9 0.00031 20.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30721.1 - 0.0074 15.9 12.6 0.012 15.2 8.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain TMEMspv1-c74-12 PF11044.3 EGC30721.1 - 0.048 13.2 3.2 0.18 11.3 2.2 2.0 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein zf-RING_4 PF14570.1 EGC30721.1 - 0.15 11.6 12.0 0.34 10.5 8.3 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGC30721.1 - 0.18 11.7 11.8 0.47 10.3 8.2 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC30721.1 - 0.29 10.8 6.4 1.2 8.9 4.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGC30721.1 - 0.45 10.0 10.2 0.87 9.1 7.1 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGC30721.1 - 0.45 10.3 4.5 1.1 9.1 3.1 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein 7tm_1 PF00001.16 EGC30721.1 - 1.7 7.7 6.6 9.9 5.2 0.0 2.1 2 0 0 2 2 2 0 7 transmembrane receptor (rhodopsin family) SieB PF14163.1 EGC30721.1 - 2.4 7.7 9.8 0.56 9.7 2.5 2.5 2 1 0 2 2 2 0 Superinfection exclusion protein B U-box PF04564.10 EGC30721.1 - 5.6 6.9 6.3 9.4 6.2 0.0 3.2 3 1 0 3 3 3 0 U-box domain DUF4446 PF14584.1 EGC30721.1 - 9.8 5.9 11.8 0.64 9.8 1.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Ank PF00023.25 EGC30722.1 - 4.4e-20 70.4 1.4 4.9e-09 35.5 0.3 2.3 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGC30722.1 - 1.9e-19 69.2 1.0 1.5e-09 37.7 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC30722.1 - 1.4e-18 66.9 0.5 2e-18 66.4 0.4 1.2 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC30722.1 - 6.1e-18 64.8 2.2 3.1e-12 46.6 0.1 2.9 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC30722.1 - 1.4e-14 52.6 0.5 3.2e-06 26.8 0.0 2.5 2 0 0 2 2 2 2 Ankyrin repeat FKBP_C PF00254.23 EGC30723.1 - 1.4e-20 73.1 0.0 1.6e-20 72.8 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Dimer_Tnp_hAT PF05699.9 EGC30724.1 - 0.006 16.1 0.0 0.0082 15.7 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ArfGap PF01412.13 EGC30724.1 - 0.1 12.3 1.5 0.12 12.1 1.0 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf zf-B_box PF00643.19 EGC30725.1 - 0.0017 18.1 5.1 0.0017 18.1 3.5 3.0 2 0 0 2 2 2 1 B-box zinc finger Pox_MCEL PF03291.11 EGC30726.1 - 2.1e-29 102.4 5.3 2.7e-27 95.5 3.7 2.3 1 1 0 1 1 1 1 mRNA capping enzyme Methyltransf_12 PF08242.7 EGC30726.1 - 1.2e-06 28.9 1.1 0.0017 18.7 0.5 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_11 PF08241.7 EGC30726.1 - 7.4e-06 26.3 0.1 0.11 13.0 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_25 PF13649.1 EGC30726.1 - 0.00017 21.8 0.0 0.38 11.1 0.0 2.4 1 1 1 2 2 2 2 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30726.1 - 0.00023 21.7 0.0 0.00056 20.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC30726.1 - 0.0064 16.2 0.0 0.014 15.1 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain LRR_9 PF14580.1 EGC30727.1 - 7.9e-06 25.5 2.4 3.8e-05 23.3 1.7 2.1 1 1 0 1 1 1 1 Leucine-rich repeat LRR_7 PF13504.1 EGC30727.1 - 0.041 14.0 14.7 6 7.5 0.1 6.3 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EGC30727.1 - 0.46 10.7 25.2 0.69 10.1 0.1 7.1 5 0 0 5 5 5 0 Leucine Rich repeat Smr PF01713.16 EGC30728.1 - 6.5e-12 45.4 0.2 1.6e-11 44.1 0.0 1.7 2 0 0 2 2 2 1 Smr domain DUF1771 PF08590.5 EGC30728.1 - 8.4e-06 25.7 9.2 1.6e-05 24.7 6.4 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Clusterin PF01093.12 EGC30728.1 - 0.04 12.7 2.9 0.047 12.4 2.0 1.0 1 0 0 1 1 1 0 Clusterin OmpH PF03938.9 EGC30728.1 - 0.12 12.2 11.7 0.19 11.6 8.1 1.4 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Cep57_CLD_2 PF14197.1 EGC30728.1 - 0.4 10.6 6.7 0.99 9.3 4.6 1.8 1 1 0 1 1 1 0 Centrosome localisation domain of PPC89 GreA_GreB_N PF03449.10 EGC30728.1 - 0.78 9.8 7.0 2 8.5 4.4 2.0 2 1 0 2 2 2 0 Transcription elongation factor, N-terminal Mnd1 PF03962.10 EGC30728.1 - 2 8.0 12.8 2.4 7.7 7.8 1.8 2 0 0 2 2 2 0 Mnd1 family DUF4407 PF14362.1 EGC30728.1 - 2.8 6.8 6.7 3.7 6.4 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Vfa1 PF08432.5 EGC30728.1 - 6.4 6.7 13.2 7.6 6.5 9.1 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 VIT1 PF01988.14 EGC30728.1 - 7 6.0 6.3 9.2 5.6 4.4 1.2 1 0 0 1 1 1 0 VIT family FliT PF05400.8 EGC30728.1 - 7.4 7.0 14.7 13 6.2 0.0 3.1 1 1 2 3 3 3 0 Flagellar protein FliT Condensin2nSMC PF12422.3 EGC30729.1 - 1.7e-43 147.9 1.5 1.2e-42 145.1 1.0 2.7 1 0 0 1 1 1 1 Condensin II non structural maintenance of chromosomes subunit HEAT PF02985.17 EGC30729.1 - 3.3e-05 23.5 0.5 0.77 9.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Oxysterol_BP PF01237.13 EGC30730.1 - 6.5e-109 363.6 7.2 1e-108 363.0 5.0 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein DUF916 PF06030.7 EGC30730.1 - 0.015 15.0 1.7 0.044 13.5 1.2 1.8 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF916) Med2 PF11214.3 EGC30730.1 - 0.29 11.1 6.9 0.42 10.6 3.8 1.9 1 1 0 1 1 1 0 Mediator complex subunit 2 OTU PF02338.14 EGC30731.1 - 3.3e-13 50.2 2.7 3.7e-13 50.1 0.0 2.2 3 0 0 3 3 3 1 OTU-like cysteine protease DUF1183 PF06682.7 EGC30731.1 - 0.0033 17.0 3.6 0.0053 16.4 2.5 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) ig PF00047.20 EGC30731.1 - 0.15 12.2 0.7 18 5.5 0.1 3.3 3 0 0 3 3 3 0 Immunoglobulin domain Shisa PF13908.1 EGC30731.1 - 2 8.5 14.5 20 5.2 10.0 2.2 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator PAT1 PF09770.4 EGC30731.1 - 3.3 5.8 25.6 4.3 5.4 17.7 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Adeno_E1B_55K PF01696.12 EGC30733.1 - 0.56 8.6 3.4 0.68 8.3 2.3 1.0 1 0 0 1 1 1 0 Adenovirus EB1 55K protein / large t-antigen zinc_ribbon_2 PF13240.1 EGC30734.1 - 0.00025 20.4 8.8 0.00053 19.3 6.1 1.6 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EGC30734.1 - 0.0052 16.5 4.8 0.013 15.3 3.3 1.6 1 0 0 1 1 1 1 Double zinc ribbon DUF3292 PF11696.3 EGC30734.1 - 0.015 13.1 3.2 0.022 12.6 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3292) zf-ribbon_3 PF13248.1 EGC30734.1 - 0.041 13.1 10.3 0.22 10.7 7.2 2.1 1 1 0 1 1 1 0 zinc-ribbon domain PAT1 PF09770.4 EGC30734.1 - 0.046 11.9 9.2 0.063 11.5 6.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF2616 PF11077.3 EGC30734.1 - 0.39 10.2 3.6 0.63 9.5 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) Nudix_N_2 PF14803.1 EGC30734.1 - 0.47 10.1 10.7 1 9.1 1.9 2.4 2 0 0 2 2 2 0 Nudix N-terminal YqzE PF14038.1 EGC30734.1 - 2.7 7.8 6.2 5.2 6.8 4.3 1.5 1 0 0 1 1 1 0 YqzE-like protein UPF0547 PF10571.4 EGC30734.1 - 4.9 6.9 12.9 3.6 7.3 2.5 2.4 1 1 1 2 2 2 0 Uncharacterised protein family UPF0547 ICAT PF06384.6 EGC30735.1 - 3.4e-30 103.6 0.6 3.4e-30 103.6 0.4 2.0 2 1 0 2 2 2 1 Beta-catenin-interacting protein ICAT GvpG PF05120.7 EGC30735.1 - 0.0004 20.1 12.7 0.0057 16.4 0.1 2.7 2 1 0 2 2 2 2 Gas vesicle protein G DUF3313 PF11769.3 EGC30735.1 - 0.0028 17.0 0.4 0.0046 16.3 0.3 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3313) Dynamin_M PF01031.15 EGC30735.1 - 0.017 13.9 2.3 0.028 13.1 1.6 1.3 1 0 0 1 1 1 0 Dynamin central region CAMP_factor PF07373.6 EGC30735.1 - 0.021 14.3 3.0 0.022 14.2 1.1 1.7 1 1 1 2 2 2 0 CAMP factor (Cfa) PCAF_N PF06466.6 EGC30735.1 - 0.13 11.5 0.4 0.2 10.9 0.3 1.3 1 0 0 1 1 1 0 PCAF (P300/CBP-associated factor) N-terminal domain Colicin-DNase PF12639.2 EGC30735.1 - 0.23 11.7 1.4 1.5 9.0 0.1 2.3 1 1 1 2 2 2 0 DNase/tRNase domain of colicin-like bacteriocin DUF883 PF05957.8 EGC30735.1 - 0.41 11.0 2.1 0.72 10.2 0.8 2.0 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) IL3 PF02059.10 EGC30735.1 - 2.3 8.2 6.6 1.8 8.5 2.0 2.1 1 1 1 2 2 2 0 Interleukin-3 DUF217 PF02697.9 EGC30735.1 - 2.5 8.4 8.3 0.49 10.6 1.2 2.7 3 1 0 3 3 3 0 Uncharacterized ACR, COG1753 DUF972 PF06156.8 EGC30735.1 - 2.8 8.3 11.3 8.4 6.7 2.3 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF972) IncA PF04156.9 EGC30735.1 - 8.4 5.9 10.8 1.4 8.4 5.0 1.6 2 0 0 2 2 2 0 IncA protein COX17 PF05051.8 EGC30737.1 - 8.1e-24 83.3 8.1 9.4e-24 83.1 5.6 1.1 1 0 0 1 1 1 1 Cytochrome C oxidase copper chaperone (COX17) SMK-1 PF04802.10 EGC30738.1 - 2.7e-19 69.4 27.7 9.1e-11 41.6 1.4 5.5 4 1 2 6 6 6 3 Component of IIS longevity pathway SMK-1 FUN14 PF04930.10 EGC30739.1 - 8.9e-21 74.0 1.2 8.9e-21 74.0 0.8 2.1 2 1 0 2 2 2 1 FUN14 family SBP_bac_10 PF07596.6 EGC30739.1 - 0.012 15.6 0.5 0.014 15.4 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1559) E1-E2_ATPase PF00122.15 EGC30740.1 - 1.2e-14 53.9 0.0 4.7e-14 51.9 0.0 2.0 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC30740.1 - 2.4e-14 54.2 0.0 8.1e-13 49.2 0.0 2.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC30740.1 - 3.4e-14 53.4 0.0 1.3e-13 51.5 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC30740.1 - 4.6e-12 45.7 0.1 2.3e-11 43.4 0.0 2.3 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Lustrin_cystein PF14625.1 EGC30741.1 - 6.6e-05 22.8 20.4 0.0066 16.4 2.4 3.6 1 1 2 3 3 3 2 Lustrin, cysteine-rich repeated domain Granulin PF00396.13 EGC30741.1 - 0.099 12.7 17.9 3 8.0 1.6 3.7 1 1 2 3 3 3 0 Granulin HPS3_Mid PF14762.1 EGC30741.1 - 0.12 10.8 0.6 0.15 10.5 0.4 1.1 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3, middle region Dickkopf_N PF04706.7 EGC30741.1 - 0.95 9.6 14.3 3.4 7.9 4.0 2.6 1 1 1 2 2 2 0 Dickkopf N-terminal cysteine-rich region EB PF01683.13 EGC30741.1 - 1.3 9.1 13.0 2.8 8.0 6.0 2.4 1 1 1 2 2 2 0 EB module Sporozoite_P67 PF05642.6 EGC30741.1 - 4.5 5.0 10.6 5.4 4.7 7.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Abhydrolase_5 PF12695.2 EGC30742.1 - 1.6e-07 31.1 0.0 3e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC30742.1 - 1.6e-06 27.5 0.0 3.6e-06 26.3 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGC30742.1 - 0.0081 15.7 0.0 0.022 14.3 0.0 1.7 1 0 0 1 1 1 1 alpha/beta hydrolase fold Imm-NTF2-2 PF15631.1 EGC30742.1 - 0.049 13.6 0.4 0.24 11.3 0.3 2.3 1 0 0 1 1 1 0 NTF2 fold immunity protein PGAP1 PF07819.8 EGC30742.1 - 0.057 13.0 0.0 0.15 11.6 0.0 1.6 1 0 0 1 1 1 0 PGAP1-like protein Abhydrolase_6 PF12697.2 EGC30742.1 - 0.27 11.0 0.1 0.91 9.3 0.0 1.6 1 1 0 2 2 2 0 Alpha/beta hydrolase family AKNA PF12443.3 EGC30743.1 - 0.26 11.3 9.1 1.2 9.2 0.1 3.2 1 1 2 3 3 3 0 AT-hook-containing transcription factor Tropomyosin_1 PF12718.2 EGC30743.1 - 2.1 8.1 18.1 1.8 8.4 4.7 2.2 2 0 0 2 2 2 0 Tropomyosin like DUF1599 PF07659.6 EGC30743.1 - 6.8 6.8 9.5 4.5 7.4 0.3 2.8 2 1 0 2 2 2 0 Domain of Unknown Function (DUF1599) Uds1 PF15456.1 EGC30743.1 - 7.8 6.5 10.7 0.81 9.6 2.5 2.2 1 1 2 3 3 3 0 Up-regulated During Septation Oxidored_FMN PF00724.15 EGC30744.1 - 4.6e-78 262.6 0.0 5.3e-78 262.4 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGC30744.1 - 0.064 12.0 0.0 0.11 11.2 0.0 1.3 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) Erf4 PF10256.4 EGC30745.1 - 6.1e-08 32.5 5.5 1.7e-06 27.9 0.1 3.1 3 0 0 3 3 3 1 Golgin subfamily A member 7/ERF4 family ABC2_membrane_2 PF12679.2 EGC30745.1 - 0.057 12.2 0.1 0.39 9.5 0.1 1.9 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF4282 PF14110.1 EGC30745.1 - 0.069 13.3 1.1 0.13 12.4 0.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4282) DUF4064 PF13273.1 EGC30745.1 - 0.13 12.4 3.2 3.5 7.7 0.1 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF4064) Oxidored_q3 PF00499.15 EGC30745.1 - 1.4 8.6 8.7 0.08 12.7 1.9 1.9 2 1 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Tetraspannin PF00335.15 EGC30745.1 - 5.2 6.2 15.0 0.027 13.7 1.8 2.3 2 0 0 2 2 2 0 Tetraspanin family ETRAMP PF09716.5 EGC30745.1 - 7.8 6.5 10.9 52 3.8 4.1 3.1 2 1 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Rifin_STEVOR PF02009.11 EGC30746.1 - 0.003 17.2 0.1 0.0047 16.6 0.1 1.4 1 0 0 1 1 1 1 Rifin/stevor family DUF912 PF06024.7 EGC30746.1 - 0.018 15.1 0.1 0.03 14.3 0.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EGC30746.1 - 0.043 13.5 1.3 0.069 12.8 0.9 1.2 1 0 0 1 1 1 0 TMEM154 protein family OTU PF02338.14 EGC30747.1 - 1.7e-11 44.7 0.6 3.1e-11 43.8 0.4 1.3 1 1 0 1 1 1 1 OTU-like cysteine protease Apt1 PF10351.4 EGC30748.1 - 2.9 6.6 10.6 3.8 6.2 7.4 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Macoilin PF09726.4 EGC30748.1 - 5 5.2 12.3 7.6 4.6 8.5 1.2 1 0 0 1 1 1 0 Transmembrane protein AFP PF02420.10 EGC30749.1 - 0.31 11.2 5.4 1.7 9.0 0.5 5.1 3 0 0 3 3 3 0 Insect antifreeze protein repeat FERM_N PF09379.5 EGC30750.1 - 2.7e-06 27.3 0.4 0.0046 16.9 0.0 3.5 3 1 0 3 3 3 2 FERM N-terminal domain Fib_alpha PF08702.5 EGC30750.1 - 0.0081 16.2 16.1 0.0081 16.2 11.2 4.8 2 1 1 4 4 4 1 Fibrinogen alpha/beta chain family TUG-UBL1 PF11470.3 EGC30750.1 - 0.013 15.3 0.9 0.066 13.1 0.0 2.7 3 0 0 3 3 3 0 GLUT4 regulating protein TUG DUF3138 PF11336.3 EGC30750.1 - 0.48 8.5 1.1 1 7.4 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) DDE_Tnp_4 PF13359.1 EGC30751.1 - 4.6e-07 29.5 0.0 1e-06 28.4 0.0 1.6 1 0 0 1 1 1 1 DDE superfamily endonuclease IncA PF04156.9 EGC30754.1 - 0.3 10.6 12.9 0.27 10.8 0.7 2.2 2 0 0 2 2 2 0 IncA protein DUF99 PF01949.11 EGC30754.1 - 0.3 10.1 2.2 1.4 7.9 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function DUF99 BDV_P24 PF06595.6 EGC30754.1 - 0.32 10.7 1.9 0.66 9.6 0.2 2.0 1 1 1 2 2 2 0 Borna disease virus P24 protein ING PF12998.2 EGC30754.1 - 0.4 10.9 13.2 0.12 12.6 6.0 2.3 2 1 0 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding EST1_DNA_bind PF10373.4 EGC30754.1 - 0.68 9.1 9.0 2.7 7.1 6.2 1.9 1 1 0 1 1 1 0 Est1 DNA/RNA binding domain Mer2 PF09074.5 EGC30754.1 - 4.6 7.1 15.9 4.8 7.0 5.0 2.3 2 0 0 2 2 2 0 Mer2 ApoL PF05461.6 EGC30755.1 - 0.00092 18.5 2.2 0.00092 18.5 1.5 1.8 2 0 0 2 2 2 1 Apolipoprotein L DUF726 PF05277.7 EGC30755.1 - 0.035 12.9 0.3 0.064 12.1 0.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF726) BCDHK_Adom3 PF10436.4 EGC30755.1 - 0.09 12.2 1.2 0.33 10.4 0.1 2.2 2 0 0 2 2 2 0 Mitochondrial branched-chain alpha-ketoacid dehydrogenase kinase IncA PF04156.9 EGC30755.1 - 5.2 6.6 14.3 0.058 12.9 2.6 2.6 3 0 0 3 3 3 0 IncA protein YtxH PF12732.2 EGC30755.1 - 9.7 6.6 10.2 6.2 7.2 0.1 3.8 3 1 1 4 4 4 0 YtxH-like protein FNIP PF05725.7 EGC30756.1 - 4.5e-09 36.1 31.7 1.2e-05 25.1 1.2 6.9 3 2 3 6 6 6 5 FNIP Repeat zf-TRAF PF02176.13 EGC30757.1 - 2.4e-17 63.0 18.2 1.4e-11 44.5 5.2 4.3 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC30757.1 - 3.8e-07 30.0 14.3 3.8e-07 30.0 9.9 3.4 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.21 EGC30757.1 - 5.7e-07 29.8 2.7 1.9e-06 28.1 1.9 1.9 1 0 0 1 1 1 1 MATH domain zf-C3HC4_3 PF13920.1 EGC30757.1 - 6.2e-06 25.7 10.5 6.2e-06 25.7 7.2 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC30757.1 - 0.00034 20.3 21.2 0.0017 18.0 1.1 4.6 2 1 3 5 5 5 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC30757.1 - 0.0064 16.2 11.5 0.0064 16.2 8.0 3.4 3 0 0 3 3 3 1 Ring finger domain MCC-bdg_PDZ PF10506.4 EGC30757.1 - 0.073 12.9 0.2 0.23 11.3 0.2 1.9 1 0 0 1 1 1 0 PDZ domain of MCC-2 bdg protein for Usher syndrome bZIP_1 PF00170.16 EGC30757.1 - 0.95 9.4 5.3 2 8.4 1.8 3.0 2 1 0 2 2 2 0 bZIP transcription factor YvrJ PF12841.2 EGC30757.1 - 4.8 6.5 5.9 32 3.9 0.1 3.9 3 1 1 4 4 4 0 YvrJ protein family DDRGK PF09756.4 EGC30758.1 - 1.3e-52 177.9 31.3 1.3e-52 177.9 21.7 2.2 2 1 0 2 2 2 1 DDRGK domain CAF-1_p150 PF11600.3 EGC30758.1 - 0.0023 17.3 38.2 0.0046 16.3 26.5 1.5 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF1183 PF06682.7 EGC30758.1 - 2.1 7.8 6.5 3.7 7.0 4.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) CAP_GLY PF01302.20 EGC30759.1 - 2e-19 69.0 1.6 3.6e-19 68.2 1.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain Elongin_A PF06881.6 EGC30759.1 - 6.1e-19 68.4 0.2 2.4e-18 66.4 0.1 2.1 1 0 0 1 1 1 1 RNA polymerase II transcription factor SIII (Elongin) subunit A LRR_4 PF12799.2 EGC30759.1 - 2e-16 59.1 31.2 3.4e-07 29.7 2.3 4.9 4 1 1 5 5 5 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30759.1 - 3.3e-12 45.9 23.8 1.4e-09 37.5 6.0 3.5 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 EGC30759.1 - 2.3e-09 36.3 22.8 0.14 12.3 0.6 7.0 6 0 0 6 6 6 4 Leucine Rich repeat LRR_7 PF13504.1 EGC30759.1 - 8.3e-07 28.2 14.2 2 8.9 0.1 6.8 6 0 0 6 6 6 3 Leucine rich repeat LRR_1 PF00560.28 EGC30759.1 - 8.7e-07 28.1 24.2 0.34 11.0 0.2 6.9 7 0 0 7 7 7 4 Leucine Rich Repeat LRR_9 PF14580.1 EGC30759.1 - 0.00098 18.7 9.8 0.21 11.1 1.8 3.1 1 1 2 3 3 3 3 Leucine-rich repeat AIRS_C PF02769.17 EGC30759.1 - 0.043 13.8 0.0 0.087 12.8 0.0 1.4 1 0 0 1 1 1 0 AIR synthase related protein, C-terminal domain GRP PF07172.6 EGC30761.1 - 0.016 15.6 0.3 0.029 14.8 0.2 1.4 1 0 0 1 1 1 0 Glycine rich protein family Tetraspannin PF00335.15 EGC30761.1 - 3.7 6.7 8.9 4.8 6.3 2.3 2.4 1 1 0 2 2 2 0 Tetraspanin family Acetyltransf_1 PF00583.19 EGC30762.1 - 3.9e-14 52.4 0.1 5.5e-14 51.9 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC30762.1 - 7e-08 32.5 0.7 1.2e-07 31.7 0.5 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC30762.1 - 1e-07 32.0 1.1 1.7e-07 31.3 0.7 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC30762.1 - 1.4e-06 27.9 0.0 2.3e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGC30762.1 - 3.6e-06 27.1 0.0 5e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC30762.1 - 7e-05 23.0 0.0 0.00015 21.9 0.0 1.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Baculo_E56 PF04639.7 EGC30762.1 - 0.00026 19.7 1.2 0.00042 19.0 0.8 1.3 1 0 0 1 1 1 1 Baculoviral E56 protein, specific to ODV envelope Acetyltransf_8 PF13523.1 EGC30762.1 - 0.004 17.0 0.0 0.0055 16.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGC30762.1 - 0.025 14.1 0.0 0.038 13.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OppC_N PF12911.2 EGC30762.1 - 0.6 9.5 3.8 1.6 8.1 2.6 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C FbpA PF05833.6 EGC30763.1 - 4.4e-41 140.9 19.6 4.4e-41 140.9 13.6 4.4 4 1 0 4 4 4 1 Fibronectin-binding protein A N-terminus (FbpA) DUF3441 PF11923.3 EGC30763.1 - 1.3e-26 92.3 0.1 1.3e-26 92.3 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3441) DUF814 PF05670.8 EGC30763.1 - 1.6e-23 82.3 0.1 7e-23 80.3 0.0 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF814) LRR_4 PF12799.2 EGC30764.1 - 1.2e-36 123.6 44.6 2.2e-07 30.3 3.9 8.3 3 1 7 11 11 11 9 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC30764.1 - 8.1e-29 99.1 41.8 1.1e-07 31.4 5.4 6.9 2 2 6 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EGC30764.1 - 4.5e-23 77.7 45.4 0.018 14.9 0.2 13.4 12 1 1 13 13 13 10 Leucine Rich Repeat LRR_7 PF13504.1 EGC30764.1 - 9.6e-16 55.1 31.9 0.14 12.4 1.3 12.4 12 0 0 12 12 12 4 Leucine rich repeat Filamin PF00630.14 EGC30764.1 - 5.9e-15 55.6 0.1 1e-14 54.8 0.1 1.4 1 0 0 1 1 1 1 Filamin/ABP280 repeat LRR_6 PF13516.1 EGC30764.1 - 1.1e-10 40.3 41.2 0.93 9.7 0.0 11.6 9 2 2 11 11 11 5 Leucine Rich repeat LRR_9 PF14580.1 EGC30764.1 - 0.0028 17.2 14.2 3.7 7.0 0.3 4.9 1 1 4 5 5 5 4 Leucine-rich repeat Ank_2 PF12796.2 EGC30765.1 - 4.2e-23 81.4 0.0 6.8e-06 26.3 0.0 6.9 3 2 2 5 5 5 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC30765.1 - 8.4e-12 45.2 2.0 0.56 10.7 0.0 8.3 6 1 2 8 8 8 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC30765.1 - 2.2e-06 27.3 5.2 3.3 8.2 0.0 9.9 12 0 0 12 12 12 1 Ankyrin repeat Ank PF00023.25 EGC30765.1 - 0.018 14.8 0.6 5.4 7.0 0.0 5.1 7 0 0 7 7 7 0 Ankyrin repeat DUF624 PF04854.9 EGC30765.1 - 0.09 12.6 5.4 1.4 8.8 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function, DUF624 AsmA_2 PF13502.1 EGC30765.1 - 0.1 11.9 0.5 1.3 8.3 0.0 2.2 2 0 0 2 2 2 0 AsmA-like C-terminal region EF-hand_8 PF13833.1 EGC30766.1 - 2.6e-06 26.9 2.4 0.00032 20.2 1.0 3.3 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC30766.1 - 7.3e-05 21.7 1.5 0.038 13.2 0.2 3.3 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGC30766.1 - 0.00026 21.0 1.6 0.012 15.6 0.6 3.1 2 1 1 3 3 3 1 EF-hand domain pair EF-hand_6 PF13405.1 EGC30766.1 - 0.00028 20.5 2.7 0.095 12.6 0.1 3.7 3 0 0 3 3 3 1 EF-hand domain EF-hand_5 PF13202.1 EGC30766.1 - 0.0069 15.6 0.1 0.03 13.6 0.1 2.2 1 0 0 1 1 1 1 EF hand UBA PF00627.26 EGC30766.1 - 0.016 15.0 0.0 0.042 13.6 0.0 1.6 1 0 0 1 1 1 0 UBA/TS-N domain NARP1 PF12569.3 EGC30766.1 - 2.2 6.9 17.7 4.2 5.9 12.3 1.4 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Cellulose_synt PF03552.9 EGC30766.1 - 5.6 5.1 9.7 9 4.4 6.7 1.2 1 0 0 1 1 1 0 Cellulose synthase Kelch_1 PF01344.20 EGC30768.1 - 8.4e-05 22.0 0.0 8.4e-05 22.0 0.0 2.9 3 0 0 3 3 3 1 Kelch motif Kelch_4 PF13418.1 EGC30768.1 - 0.00087 19.0 0.6 0.006 16.3 0.0 2.4 2 1 0 2 2 2 1 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC30768.1 - 0.0053 16.8 0.0 0.0053 16.8 0.0 2.3 3 0 0 3 3 3 1 Kelch motif Kelch_5 PF13854.1 EGC30768.1 - 0.12 12.3 0.0 0.57 10.2 0.0 2.1 2 0 0 2 2 2 0 Kelch motif Solute_trans_a PF03619.11 EGC30769.1 - 2.5e-33 115.5 21.5 3.9e-33 114.9 14.9 1.3 1 0 0 1 1 1 1 Organic solute transporter Ostalpha DUF656 PF04920.7 EGC30769.1 - 0.031 13.9 1.8 0.069 12.8 0.5 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF656) Phage_pRha PF09669.5 EGC30769.1 - 0.2 12.0 2.5 7 7.0 0.0 2.3 2 0 0 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Methyltransf_2 PF00891.13 EGC30770.1 - 1.4e-42 145.5 0.0 2.1e-42 145.0 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_18 PF12847.2 EGC30770.1 - 5.8e-05 23.6 0.0 0.00011 22.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC30770.1 - 0.0029 17.3 0.0 0.0048 16.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CheR PF01739.13 EGC30770.1 - 0.016 14.4 0.0 0.042 13.1 0.0 1.6 2 0 0 2 2 2 0 CheR methyltransferase, SAM binding domain EF-hand_1 PF00036.27 EGC30771.1 - 1.2e-13 49.2 0.1 1.7e-07 30.0 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGC30771.1 - 3.4e-13 49.5 0.0 4.2e-13 49.2 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EGC30771.1 - 5.6e-12 45.0 0.1 6.2e-08 32.1 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC30771.1 - 2.2e-09 36.3 0.0 6.8e-07 28.6 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_9 PF14658.1 EGC30771.1 - 1.1e-05 25.1 0.0 1.4e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain EFhand_Ca_insen PF08726.5 EGC30771.1 - 0.00016 21.6 0.2 0.00038 20.3 0.2 1.6 1 1 0 1 1 1 1 Ca2+ insensitive EF hand EF-hand_5 PF13202.1 EGC30771.1 - 0.0066 15.7 0.0 0.012 14.9 0.0 1.5 1 0 0 1 1 1 1 EF hand Pkinase_C PF00433.19 EGC30772.1 - 0.023 15.2 1.4 0.023 15.2 1.0 2.7 2 1 0 2 2 2 0 Protein kinase C terminal domain Menin PF05053.8 EGC30772.1 - 0.41 8.7 7.4 0.47 8.5 5.2 1.1 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EGC30773.1 - 3.9e-47 160.5 0.1 4.5e-47 160.3 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30773.1 - 8.1e-32 110.3 0.0 9.1e-32 110.1 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase SEP PF08059.8 EGC30773.1 - 0.12 12.7 0.0 0.46 10.8 0.0 2.0 2 0 0 2 2 2 0 SEP domain Na_H_Exchanger PF00999.16 EGC30774.1 - 3.3e-71 239.8 39.9 4.5e-71 239.3 27.7 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Hydrolase_6 PF13344.1 EGC30774.1 - 0.15 11.9 1.5 0.25 11.2 0.2 1.9 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase P21-Arc PF04062.9 EGC30776.1 - 5.3e-71 237.9 0.0 5.8e-71 237.8 0.0 1.0 1 0 0 1 1 1 1 ARP2/3 complex ARPC3 (21 kDa) subunit Cupin_8 PF13621.1 EGC30777.1 - 4.1e-67 226.3 1.0 5.2e-67 225.9 0.7 1.1 1 0 0 1 1 1 1 Cupin-like domain p450 PF00067.17 EGC30778.1 - 1.3e-93 314.1 0.0 1.4e-93 313.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 INT_SG_DDX_CT_C PF15300.1 EGC30778.1 - 0.12 11.8 0.3 0.71 9.3 0.2 2.3 1 1 0 1 1 1 0 INTS6/SAGE1/DDX26B/CT45 C-terminus ADK PF00406.17 EGC30779.1 - 2.3e-43 147.6 0.0 2.8e-43 147.3 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGC30779.1 - 8e-15 54.2 0.0 1.4e-14 53.4 0.0 1.4 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_33 PF13671.1 EGC30779.1 - 8.3e-11 41.9 0.0 1.2e-10 41.4 0.0 1.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC30779.1 - 2.3e-09 38.1 0.0 2.9e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC30779.1 - 7.6e-09 35.9 0.0 1.7e-08 34.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC30779.1 - 9.1e-06 24.9 0.0 2e-05 23.7 0.0 1.4 1 1 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EGC30779.1 - 0.00077 18.8 0.1 0.067 12.5 0.0 2.4 2 0 0 2 2 2 1 Thymidylate kinase AAA_22 PF13401.1 EGC30779.1 - 0.011 15.8 0.0 0.018 15.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGC30779.1 - 0.032 14.2 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 EGC30780.1 - 3.4e-09 36.4 8.0 7e-09 35.3 5.6 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC30780.1 - 2.8e-08 33.2 10.4 8.1e-08 31.7 7.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC30780.1 - 8.7e-07 28.5 5.8 2e-06 27.3 4.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30780.1 - 3.1e-06 27.1 4.1 9.8e-06 25.5 2.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC30780.1 - 1.1e-05 25.3 10.0 2.6e-05 24.1 6.9 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC30780.1 - 0.00024 20.9 8.7 0.00089 19.0 6.1 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC30780.1 - 0.0039 16.7 9.3 0.0079 15.7 6.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGC30780.1 - 0.0084 15.8 8.4 0.022 14.4 5.8 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC30780.1 - 0.022 14.5 0.9 0.047 13.5 0.6 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Ctr PF04145.10 EGC30780.1 - 0.035 14.1 0.0 0.035 14.1 0.0 4.0 3 2 0 3 3 1 0 Ctr copper transporter family zf-RING_UBOX PF13445.1 EGC30780.1 - 0.094 12.4 4.6 0.35 10.6 3.2 2.1 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC30780.1 - 0.59 10.0 6.1 1.5 8.7 4.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) AAA PF00004.24 EGC30782.1 - 1.8e-62 209.3 0.4 5e-45 152.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC30782.1 - 5.2e-11 43.4 0.1 0.0014 19.4 0.0 3.7 4 0 0 4 4 2 2 AAA domain AAA_16 PF13191.1 EGC30782.1 - 9.2e-09 35.5 2.9 0.0024 17.8 0.1 3.8 2 2 1 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGC30782.1 - 1.1e-08 35.2 0.3 0.0053 16.8 0.0 3.8 2 1 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EGC30782.1 - 4.3e-08 32.4 0.0 0.00011 21.3 0.0 2.7 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_14 PF13173.1 EGC30782.1 - 6.5e-08 32.5 5.7 0.018 14.9 0.0 4.7 3 0 0 3 3 3 2 AAA domain AAA_33 PF13671.1 EGC30782.1 - 9.2e-07 28.8 0.0 0.053 13.4 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGC30782.1 - 2.5e-06 27.2 0.1 0.026 14.2 0.0 3.5 2 1 0 2 2 2 2 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGC30782.1 - 5e-06 26.6 0.0 0.0065 16.6 0.0 4.0 3 0 0 3 3 2 1 RNA helicase IstB_IS21 PF01695.12 EGC30782.1 - 6e-06 25.7 0.1 0.00086 18.7 0.1 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 EGC30782.1 - 3.7e-05 22.6 2.5 0.0094 14.7 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus AAA_25 PF13481.1 EGC30782.1 - 4.9e-05 22.8 1.6 0.044 13.1 0.1 3.1 2 1 1 3 3 3 2 AAA domain AAA_19 PF13245.1 EGC30782.1 - 5e-05 22.9 0.2 0.0052 16.5 0.1 2.5 2 0 0 2 2 2 1 Part of AAA domain NB-ARC PF00931.17 EGC30782.1 - 5.6e-05 22.1 2.2 0.061 12.1 0.4 3.4 2 1 1 3 3 3 2 NB-ARC domain UPF0079 PF02367.12 EGC30782.1 - 0.0002 20.9 0.3 1.1 8.8 0.0 3.2 3 0 0 3 3 3 2 Uncharacterised P-loop hydrolase UPF0079 Mg_chelatase PF01078.16 EGC30782.1 - 0.00039 19.6 0.1 0.021 13.9 0.1 2.5 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGC30782.1 - 0.00044 20.3 0.0 0.73 9.8 0.0 2.8 2 0 0 2 2 2 2 Sigma-54 interaction domain NACHT PF05729.7 EGC30782.1 - 0.00045 19.9 5.6 0.57 9.8 0.0 4.4 4 1 0 4 4 4 2 NACHT domain AAA_28 PF13521.1 EGC30782.1 - 0.00078 19.4 0.0 0.1 12.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGC30782.1 - 0.001 18.8 0.4 1.3 8.7 0.0 3.0 3 0 0 3 3 2 2 NTPase KaiC PF06745.8 EGC30782.1 - 0.0033 16.5 4.2 0.03 13.4 0.0 2.7 2 0 0 2 2 2 1 KaiC Sigma54_activat PF00158.21 EGC30782.1 - 0.0034 16.8 0.0 0.87 9.0 0.0 3.1 3 0 0 3 3 2 1 Sigma-54 interaction domain SKI PF01202.17 EGC30782.1 - 0.0053 16.6 0.2 3.7 7.3 0.0 3.1 3 0 0 3 3 2 1 Shikimate kinase T2SE PF00437.15 EGC30782.1 - 0.01 14.7 0.2 0.73 8.6 0.1 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_29 PF13555.1 EGC30782.1 - 0.019 14.4 1.0 2.4 7.7 0.0 3.1 3 0 0 3 3 2 0 P-loop containing region of AAA domain AAA_3 PF07726.6 EGC30782.1 - 0.021 14.4 0.2 0.72 9.4 0.0 2.8 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGC30782.1 - 0.022 15.0 0.0 0.022 15.0 0.0 5.5 4 3 1 5 5 5 0 AAA domain Zeta_toxin PF06414.7 EGC30782.1 - 0.03 13.4 0.1 0.16 11.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin AAA_24 PF13479.1 EGC30782.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.8 4 0 0 4 4 4 0 AAA domain DUF2040 PF09745.4 EGC30783.1 - 2e-32 111.6 30.2 2e-32 111.6 20.9 1.5 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 55 (DUF2040) p450 PF00067.17 EGC30784.1 - 1.2e-91 307.6 0.7 1.3e-91 307.4 0.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 Transpep_BrtH PF14399.1 EGC30784.1 - 0.13 11.4 0.1 0.25 10.5 0.0 1.3 1 0 0 1 1 1 0 NlpC/p60-like transpeptidase Cullin PF00888.17 EGC30785.1 - 6.4e-145 484.0 38.9 7.6e-145 483.7 27.0 1.1 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGC30785.1 - 1.1e-24 85.9 0.3 1.1e-24 85.9 0.2 3.9 4 0 0 4 4 4 1 Cullin protein neddylation domain Enkurin PF13864.1 EGC30785.1 - 1.4 9.2 10.6 4.7 7.4 0.4 4.0 3 1 1 4 4 4 0 Calmodulin-binding DUF61 PF01886.11 EGC30786.1 - 0.0024 17.7 0.2 0.79 9.5 0.0 2.2 2 0 0 2 2 2 2 Protein of unknown function DUF61 Chordopox_E11 PF06138.7 EGC30786.1 - 0.27 11.3 1.9 0.33 11.0 0.3 1.9 2 1 0 2 2 2 0 Chordopoxvirus E11 protein Peptidase_C1 PF00112.18 EGC30787.1 - 1.2e-41 142.9 3.8 1.2e-41 142.9 2.6 1.6 2 0 0 2 2 2 1 Papain family cysteine protease CAP PF00188.21 EGC30787.1 - 2.3e-15 57.1 9.2 2.3e-15 57.1 6.3 2.3 3 0 0 3 3 3 1 Cysteine-rich secretory protein family PfkB PF00294.19 EGC30788.1 - 3.8e-64 216.6 0.4 4.4e-64 216.4 0.3 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase TIG PF01833.19 EGC30790.1 - 7.8e-05 22.5 15.4 0.046 13.7 1.1 4.6 4 0 0 4 4 4 3 IPT/TIG domain LRR_8 PF13855.1 EGC30790.1 - 0.00037 20.1 10.3 0.035 13.8 0.3 4.2 3 1 0 3 3 3 2 Leucine rich repeat LRR_4 PF12799.2 EGC30790.1 - 0.0008 18.9 17.0 1.4 8.5 1.7 4.9 3 2 0 3 3 3 3 Leucine Rich repeats (2 copies) Glutaredoxin2_C PF04399.8 EGC30790.1 - 0.072 12.6 0.1 0.19 11.3 0.1 1.7 1 0 0 1 1 1 0 Glutaredoxin 2, C terminal domain zf-RING_2 PF13639.1 EGC30791.1 - 2.3e-08 33.7 8.1 4e-08 32.9 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC30791.1 - 1.2e-07 31.2 10.3 2.7e-07 30.1 7.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC30791.1 - 2.9e-07 30.0 6.5 5.7e-07 29.1 4.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC30791.1 - 1.5e-06 28.1 10.3 3.1e-06 27.0 7.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC30791.1 - 0.00036 20.5 9.0 0.0011 18.9 6.2 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC30791.1 - 0.00084 19.0 9.0 0.0019 17.8 6.3 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC30791.1 - 0.014 15.2 8.1 0.035 13.9 5.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC30791.1 - 0.031 14.1 1.8 0.068 13.0 1.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC30791.1 - 0.048 13.3 6.2 0.18 11.5 4.3 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGC30791.1 - 0.13 11.9 12.3 0.025 14.1 5.9 1.8 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_3 PF14369.1 EGC30791.1 - 0.96 9.5 8.6 1.1 9.2 3.4 2.6 2 0 0 2 2 2 0 zinc-finger DZR PF12773.2 EGC30791.1 - 1.3 8.8 6.1 5.1 7.0 4.2 2.0 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EGC30791.1 - 6.9 6.6 10.5 92 3.0 6.6 2.8 1 1 1 2 2 2 0 IBR domain BRCT PF00533.21 EGC30792.1 - 0.0035 17.4 0.4 0.022 14.9 0.0 2.6 2 1 1 3 3 3 1 BRCA1 C Terminus (BRCT) domain Trypan_PARP PF05887.6 EGC30792.1 - 1.8 8.3 7.7 3.6 7.4 5.4 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Leo1 PF04004.8 EGC30793.1 - 1.5e-47 161.4 1.0 1.5e-47 161.4 0.7 3.4 3 1 0 3 3 3 1 Leo1-like protein Podoplanin PF05808.6 EGC30794.1 - 0.031 13.8 0.7 0.054 13.0 0.0 1.8 2 0 0 2 2 2 0 Podoplanin Inhibitor_I29 PF08246.7 EGC30794.1 - 0.088 13.0 0.5 0.58 10.4 0.0 2.4 2 0 0 2 2 2 0 Cathepsin propeptide inhibitor domain (I29) Palm_thioest PF02089.10 EGC30795.1 - 7.8e-99 330.1 0.1 9.4e-99 329.8 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EGC30795.1 - 0.00017 21.1 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF915 PF06028.6 EGC30795.1 - 0.021 13.9 0.0 0.047 12.7 0.0 1.5 1 1 1 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) bPH_4 PF06713.6 EGC30795.1 - 0.031 14.1 0.0 0.096 12.5 0.0 1.8 2 0 0 2 2 2 0 Bacterial PH domain Lipase_2 PF01674.13 EGC30795.1 - 0.034 13.4 0.0 0.14 11.4 0.0 1.9 1 1 0 1 1 1 0 Lipase (class 2) FSH1 PF03959.8 EGC30795.1 - 0.11 11.8 0.0 0.22 10.9 0.0 1.5 1 0 0 1 1 1 0 Serine hydrolase (FSH1) FAD_binding_4 PF01565.18 EGC30796.1 - 1e-25 89.8 0.1 2.3e-25 88.7 0.1 1.6 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC30796.1 - 1.3e-14 53.8 4.2 2.6e-14 52.8 2.9 1.6 1 0 0 1 1 1 1 Berberine and berberine like Nyv1_N PF09426.5 EGC30796.1 - 0.04 13.4 3.0 0.044 13.3 0.1 2.5 2 1 1 3 3 3 0 Vacuolar R-SNARE Nyv1 N terminal BBE PF08031.7 EGC30797.1 - 1e-16 60.5 5.6 1e-16 60.5 3.8 2.6 3 0 0 3 3 3 1 Berberine and berberine like OST3_OST6 PF04756.8 EGC30798.1 - 4.2e-09 36.1 8.1 4.2e-09 36.1 5.6 1.7 2 0 0 2 2 2 1 OST3 / OST6 family ABC2_membrane_5 PF13346.1 EGC30798.1 - 0.031 13.5 20.2 0.041 13.1 10.6 2.4 2 1 0 2 2 2 0 ABC-2 family transporter protein DUF3530 PF12048.3 EGC30798.1 - 0.091 11.7 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3530) AtpR PF12966.2 EGC30798.1 - 2.7 8.1 11.6 0.48 10.6 1.4 3.2 4 0 0 4 4 4 0 N-ATPase, AtpR subunit DUF4293 PF14126.1 EGC30798.1 - 2.8 7.8 10.5 1.4 8.7 1.2 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4293) DUF4131 PF13567.1 EGC30798.1 - 2.8 7.3 10.5 3.8 6.9 0.4 3.3 2 2 1 3 3 3 0 Domain of unknown function (DUF4131) HEAT PF02985.17 EGC30799.1 - 0.0011 18.8 0.0 0.66 10.2 0.0 4.8 6 0 0 6 6 6 1 HEAT repeat Cohesin_HEAT PF12765.2 EGC30799.1 - 0.0034 17.3 0.1 0.011 15.6 0.1 1.9 1 0 0 1 1 1 1 HEAT repeat associated with sister chromatid cohesion PEX11 PF05648.9 EGC30799.1 - 0.0048 16.2 3.5 0.0048 16.2 2.4 2.0 2 0 0 2 2 2 1 Peroxisomal biogenesis factor 11 (PEX11) HEAT_2 PF13646.1 EGC30799.1 - 0.023 14.9 0.0 2.5 8.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 EGC30799.1 - 0.18 12.3 0.0 12 6.5 0.0 2.8 2 0 0 2 2 2 0 HEAT-like repeat DUF3299 PF11736.3 EGC30799.1 - 1.1 9.1 7.6 0.11 12.4 1.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3299) SPARC_Ca_bdg PF10591.4 EGC30800.1 - 0.093 12.7 0.0 0.093 12.7 0.0 1.2 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region FNIP PF05725.7 EGC30801.1 - 1.8e-13 50.2 13.4 2.6e-06 27.2 0.4 5.8 3 2 3 6 6 6 5 FNIP Repeat zf-B_box PF00643.19 EGC30801.1 - 2.2e-05 24.2 3.6 2.2e-05 24.2 2.5 2.1 2 0 0 2 2 2 1 B-box zinc finger PH PF00169.24 EGC30802.1 - 1e-08 35.3 0.0 1.9e-08 34.4 0.0 1.5 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGC30802.1 - 0.032 14.3 0.0 1.4 9.0 0.0 2.5 2 0 0 2 2 2 0 Pleckstrin homology domain WH2 PF02205.15 EGC30804.1 - 0.00012 21.5 0.1 0.00026 20.4 0.1 1.6 1 0 0 1 1 1 1 WH2 motif ABC1 PF03109.11 EGC30805.1 - 6.8e-29 100.2 0.0 1.6e-28 99.0 0.0 1.7 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EGC30805.1 - 0.054 13.2 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1227 PF06777.6 EGC30807.1 - 2.5e-52 176.4 0.1 5.7e-52 175.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1227) DEAD_2 PF06733.10 EGC30807.1 - 1.6e-51 174.2 3.0 1.6e-51 174.1 0.8 2.0 2 0 0 2 2 2 1 DEAD_2 Helicase_C_2 PF13307.1 EGC30807.1 - 8.1e-47 159.2 0.1 3.2e-46 157.3 0.0 2.1 2 0 0 2 2 2 1 Helicase C-terminal domain SNF2_N PF00176.18 EGC30807.1 - 7.7e-05 21.6 0.0 0.00029 19.7 0.0 1.8 1 1 0 1 1 1 1 SNF2 family N-terminal domain ResIII PF04851.10 EGC30807.1 - 0.00053 19.8 1.0 0.0063 16.3 0.0 2.9 2 1 0 3 3 3 1 Type III restriction enzyme, res subunit DEAD PF00270.24 EGC30807.1 - 0.003 17.0 4.4 0.37 10.2 0.0 3.5 4 0 0 4 4 4 2 DEAD/DEAH box helicase AAA_22 PF13401.1 EGC30807.1 - 0.063 13.4 0.4 3.2 7.9 0.2 3.0 1 1 0 1 1 1 0 AAA domain DUF3439 PF11921.3 EGC30807.1 - 0.71 9.6 6.8 1.6 8.5 4.7 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) MIR PF02815.14 EGC30808.1 - 1.8e-16 60.2 0.2 2.2e-07 30.5 0.0 3.0 1 1 2 3 3 3 3 MIR domain Ins145_P3_rec PF08709.6 EGC30808.1 - 0.00016 20.8 0.0 0.0022 17.0 0.0 2.0 1 1 1 2 2 2 2 Inositol 1,4,5-trisphosphate/ryanodine receptor PYNP_C PF07831.8 EGC30808.1 - 0.1 12.0 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 Pyrimidine nucleoside phosphorylase C-terminal domain NRDE-2 PF08424.5 EGC30809.1 - 6.7e-73 245.3 23.8 6.7e-73 245.3 16.5 4.7 4 1 0 4 4 4 2 NRDE-2, necessary for RNA interference Histone PF00125.19 EGC30810.1 - 3.1e-18 65.6 0.7 4.5e-18 65.1 0.1 1.6 2 0 0 2 2 2 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC30810.1 - 3.3e-06 27.0 0.3 3.3e-06 27.0 0.2 1.6 2 0 0 2 2 2 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone DUF3987 PF13148.1 EGC30810.1 - 0.0012 17.4 0.0 0.0012 17.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) TFIID_20kDa PF03847.8 EGC30810.1 - 0.0017 18.6 0.0 0.0036 17.5 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A CENP-S PF15630.1 EGC30810.1 - 0.041 14.0 0.1 0.076 13.2 0.1 1.4 1 0 0 1 1 1 0 Kinetochore component CENP-S CDC37_N PF03234.9 EGC30810.1 - 0.093 13.0 2.3 0.12 12.7 1.6 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding PIP5K PF01504.13 EGC30811.1 - 6.3e-56 189.2 4.1 1.6e-55 187.9 2.8 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dicty_CAR PF05462.6 EGC30811.1 - 3.7e-19 68.7 6.1 3.7e-19 68.7 4.2 2.3 2 1 0 2 2 2 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EGC30811.1 - 5e-10 38.9 3.7 7.9e-10 38.2 2.6 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Frizzled PF01534.12 EGC30811.1 - 9e-10 37.8 9.0 9.1e-09 34.5 6.3 2.0 1 1 0 1 1 1 1 Frizzled/Smoothened family membrane region 7tm_2 PF00002.19 EGC30811.1 - 9e-08 31.4 6.7 1.5e-07 30.7 4.7 1.2 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7TM_GPCR_Srsx PF10320.4 EGC30811.1 - 7.1e-06 25.3 7.3 1.1e-05 24.7 5.1 1.2 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srsx Git3_C PF11970.3 EGC30811.1 - 0.0004 20.0 0.9 0.011 15.5 0.0 2.6 1 1 1 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Neur_chan_memb PF02932.11 EGC30811.1 - 0.45 10.3 3.2 1.1 9.0 2.2 1.6 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2457 PF10446.4 EGC30811.1 - 1.6 7.3 5.1 2.4 6.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Macoilin PF09726.4 EGC30811.1 - 9.8 4.3 15.0 14 3.7 10.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Sec63 PF02889.11 EGC30813.1 - 4.1e-155 515.7 12.7 1.1e-91 307.3 2.0 2.3 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGC30813.1 - 8e-56 188.1 0.5 3.4e-29 101.4 0.2 3.5 3 0 0 3 3 3 2 DEAD/DEAH box helicase ResIII PF04851.10 EGC30813.1 - 3.3e-22 79.2 13.6 3.1e-12 46.7 0.2 4.2 3 1 1 4 4 4 2 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGC30813.1 - 2.3e-16 59.4 0.5 1.2e-06 28.3 0.0 3.2 3 0 0 3 3 3 2 Helicase conserved C-terminal domain AAA_22 PF13401.1 EGC30813.1 - 1.6e-06 28.3 0.2 0.066 13.3 0.0 3.1 2 0 0 2 2 2 2 AAA domain PhoH PF02562.11 EGC30813.1 - 9.3e-06 25.0 0.1 0.17 11.0 0.0 3.0 3 0 0 3 3 3 2 PhoH-like protein T2SE PF00437.15 EGC30813.1 - 9.7e-06 24.6 0.1 0.055 12.3 0.0 3.1 3 0 0 3 3 3 2 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGC30813.1 - 0.0057 16.0 0.1 6.6 6.1 0.0 3.3 4 0 0 4 4 4 2 IstB-like ATP binding protein AAA_19 PF13245.1 EGC30813.1 - 0.0074 16.0 0.0 0.88 9.3 0.0 2.7 3 0 0 3 3 3 1 Part of AAA domain RhoGEF PF00621.15 EGC30814.1 - 8.7e-37 126.7 15.6 8.7e-37 126.7 10.8 3.1 2 1 0 2 2 2 1 RhoGEF domain Med15 PF09606.5 EGC30814.1 - 0.00083 17.6 81.6 0.00083 17.6 56.6 1.6 2 0 0 2 2 2 1 ARC105 or Med15 subunit of Mediator complex non-fungal DnaJ PF00226.26 EGC30815.1 - 9.8e-30 102.0 3.3 9.8e-30 102.0 2.3 1.8 2 0 0 2 2 2 1 DnaJ domain PRAP PF15314.1 EGC30815.1 - 0.023 14.9 0.1 0.055 13.7 0.1 1.5 1 0 0 1 1 1 0 Proline-rich acidic protein 1, pregnancy-specific uterine DUF2232 PF09991.4 EGC30815.1 - 0.072 12.0 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) DUF3899 PF13038.1 EGC30815.1 - 0.082 13.0 1.8 0.3 11.2 0.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) B5 PF03484.10 EGC30815.1 - 0.13 12.1 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetase B5 domain SAS4 PF15460.1 EGC30815.1 - 0.29 11.0 2.1 0.43 10.4 0.4 1.9 1 1 1 2 2 2 0 Something about silencing, SAS, complex subunit 4 Glutaredoxin PF00462.19 EGC30816.1 - 1.5e-18 66.4 0.2 3.2e-18 65.4 0.0 1.6 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin_3 PF13192.1 EGC30816.1 - 0.0003 20.5 0.0 0.00041 20.1 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain DUF836 PF05768.9 EGC30816.1 - 0.0063 16.7 0.0 0.0085 16.3 0.0 1.5 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_4 PF13462.1 EGC30816.1 - 0.018 15.0 0.5 0.66 9.9 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Thioredoxin_2 PF13098.1 EGC30816.1 - 0.021 15.0 0.3 0.099 12.8 0.2 1.9 1 1 0 1 1 1 0 Thioredoxin-like domain DSBA PF01323.15 EGC30816.1 - 0.033 13.7 0.9 3.9 6.9 0.0 2.1 1 1 1 2 2 2 0 DSBA-like thioredoxin domain GST_N_3 PF13417.1 EGC30816.1 - 0.067 13.4 0.0 0.073 13.2 0.0 1.1 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain TraF PF13728.1 EGC30816.1 - 0.16 11.4 0.1 0.19 11.1 0.0 1.1 1 0 0 1 1 1 0 F plasmid transfer operon protein Nucleoside_tran PF01733.13 EGC30817.1 - 8.3e-49 166.4 21.6 8.3e-49 166.4 15.0 2.5 1 1 1 2 2 2 1 Nucleoside transporter DUF1049 PF06305.6 EGC30817.1 - 0.11 12.0 0.1 0.11 12.0 0.1 3.8 4 0 0 4 4 4 0 Protein of unknown function (DUF1049) ATP-synt_8 PF00895.15 EGC30817.1 - 0.51 10.5 0.1 0.51 10.5 0.1 6.8 7 2 1 8 8 8 0 ATP synthase protein 8 DUF843 PF05814.6 EGC30817.1 - 7.8 6.3 11.4 21 4.9 2.2 4.1 3 1 0 3 3 3 0 Baculovirus protein of unknown function (DUF843) AMMECR1 PF01871.12 EGC30818.1 - 5.9e-47 158.9 0.0 7.3e-47 158.6 0.0 1.1 1 0 0 1 1 1 1 AMMECR1 Prolamin_like PF05617.6 EGC30818.1 - 0.091 12.9 0.1 0.22 11.6 0.0 1.6 1 0 0 1 1 1 0 Prolamin-like ADH_zinc_N PF00107.21 EGC30819.1 - 3.8e-25 87.9 0.0 6e-25 87.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC30819.1 - 2.2e-17 64.1 0.0 6.3e-17 62.6 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC30819.1 - 7e-07 28.9 0.0 1.2e-06 28.2 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EAL PF00563.15 EGC30819.1 - 0.007 15.8 0.0 0.02 14.4 0.0 1.7 2 0 0 2 2 2 1 EAL domain Cullin_binding PF03556.10 EGC30820.1 - 1.8e-33 115.1 3.5 1.8e-33 115.1 2.4 2.7 2 1 1 3 3 3 1 Cullin binding UBA_4 PF14555.1 EGC30820.1 - 6.7e-11 41.5 0.0 1.4e-10 40.5 0.0 1.6 1 0 0 1 1 1 1 UBA-like domain UBA PF00627.26 EGC30820.1 - 0.036 13.9 0.0 0.21 11.4 0.0 2.1 2 0 0 2 2 2 0 UBA/TS-N domain adh_short PF00106.20 EGC30821.1 - 6.5e-09 35.9 0.0 9.9e-09 35.3 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC30821.1 - 3.4e-05 23.7 0.0 5.5e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF19 PF01579.13 EGC30821.1 - 0.036 14.0 0.7 2.8 7.8 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF19) UQ_con PF00179.21 EGC30822.1 - 7.4e-17 61.0 0.0 8.1e-17 60.9 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RNA_pol_Rpb1_1 PF04997.7 EGC30823.1 - 0.15 11.2 17.6 0.16 11.1 12.2 1.1 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 1 Neur_chan_memb PF02932.11 EGC30823.1 - 1.2 8.9 5.3 1.3 8.8 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region IF4E PF01652.13 EGC30825.1 - 4.9e-43 146.5 0.1 1.4e-42 145.0 0.1 1.8 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Annexin PF00191.15 EGC30827.1 - 4e-20 71.4 0.4 3.6e-08 33.1 0.0 3.1 3 0 0 3 3 3 3 Annexin HD_2 PF12917.2 EGC30827.1 - 0.098 12.4 0.1 0.24 11.1 0.0 1.8 2 1 0 2 2 2 0 HD containing hydrolase-like enzyme FNIP PF05725.7 EGC30830.1 - 3.2e-52 174.2 58.5 2.7e-13 49.6 0.8 9.3 3 2 8 11 11 11 10 FNIP Repeat DUF1769 PF08588.5 EGC30830.1 - 7.7e-05 22.5 9.0 1.8 8.5 0.0 6.9 4 2 5 9 9 9 2 Protein of unknown function (DUF1769) GpcrRhopsn4 PF10192.4 EGC30831.1 - 2.3e-61 207.2 35.0 3.1e-61 206.7 24.3 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain TIG PF01833.19 EGC30832.1 - 2e-11 43.7 6.4 2.4e-08 33.8 0.3 5.3 5 0 0 5 5 5 2 IPT/TIG domain LRR_8 PF13855.1 EGC30832.1 - 0.0071 16.0 7.5 0.44 10.3 0.1 4.7 3 1 1 4 4 4 1 Leucine rich repeat LRR_4 PF12799.2 EGC30832.1 - 0.19 11.3 7.1 1.3 8.7 0.0 4.4 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) Fe-S_biosyn PF01521.15 EGC30833.1 - 6.6e-14 51.7 0.4 1.2e-13 50.9 0.3 1.4 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Tubulin_2 PF13809.1 EGC30833.1 - 0.06 12.2 3.8 0.073 11.9 2.7 1.1 1 0 0 1 1 1 0 Tubulin like DUF2222 PF09984.4 EGC30833.1 - 0.1 12.0 5.6 0.14 11.5 3.9 1.2 1 0 0 1 1 1 0 Uncharacterized signal transduction histidine kinase domain (DUF2222) DUF655 PF04919.7 EGC30835.1 - 0.094 12.4 0.1 0.2 11.3 0.1 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF655) DDE_Tnp_4 PF13359.1 EGC30837.1 - 3.8e-06 26.5 6.8 0.00019 21.1 1.2 2.6 2 1 1 3 3 3 2 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EGC30837.1 - 0.018 14.5 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC30837.1 - 0.036 13.6 0.1 0.046 13.2 0.1 1.3 1 0 0 1 1 1 0 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 EGC30837.1 - 0.063 13.4 0.2 0.11 12.7 0.1 1.4 1 0 0 1 1 1 0 Transposase DDE domain Surp PF01805.15 EGC30838.1 - 3.1e-07 29.9 0.0 7.2e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 Surp module NAD_binding_1 PF00175.16 EGC30838.1 - 0.91 10.1 4.1 29 5.2 0.5 3.2 3 0 0 3 3 3 0 Oxidoreductase NAD-binding domain RhoGAP PF00620.22 EGC30840.1 - 5.5e-31 107.2 0.0 1.2e-30 106.1 0.0 1.6 1 0 0 1 1 1 1 RhoGAP domain Glyco_hydro_20 PF00728.17 EGC30841.1 - 6.1e-71 239.4 0.6 1e-70 238.6 0.4 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGC30841.1 - 3.3e-06 27.7 0.0 1.1e-05 26.1 0.0 2.0 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like BTB_2 PF02214.17 EGC30843.1 - 1.2e-20 73.4 0.2 4.1e-20 71.7 0.1 1.9 1 0 0 1 1 1 1 BTB/POZ domain Dicty_CAR PF05462.6 EGC30844.1 - 0.11 11.3 19.7 0.21 10.4 12.4 2.2 1 1 1 2 2 2 0 Slime mold cyclic AMP receptor ECF-ribofla_trS PF07155.7 EGC30844.1 - 1.4 8.5 15.0 0.016 14.8 3.7 2.4 3 0 0 3 3 3 0 ECF-type riboflavin transporter, S component Pkinase PF00069.20 EGC30845.1 - 1.8e-72 243.6 0.0 3.6e-72 242.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30845.1 - 4.6e-36 124.2 0.0 7.3e-36 123.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGC30845.1 - 1.7e-16 59.3 0.0 2.9e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EGC30845.1 - 2.8e-08 33.1 0.0 6.6e-08 31.8 0.0 1.6 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC30845.1 - 0.0006 19.6 0.0 0.024 14.3 0.1 2.3 2 0 0 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC30845.1 - 0.032 13.8 1.7 0.048 13.2 0.1 2.0 2 0 0 2 2 2 0 Choline/ethanolamine kinase RGCC PF15151.1 EGC30845.1 - 0.16 12.4 2.1 0.59 10.5 1.0 2.1 2 0 0 2 2 2 0 Response gene to complement 32 protein family CBS PF00571.23 EGC30846.1 - 2.2e-27 94.5 0.2 1.2e-09 37.7 0.0 4.4 4 0 0 4 4 4 4 CBS domain PP2C_2 PF13672.1 EGC30847.1 - 0.00038 19.9 0.1 0.0011 18.4 0.1 1.8 1 1 0 1 1 1 1 Protein phosphatase 2C HSP90 PF00183.13 EGC30848.1 - 0.0041 15.5 16.0 0.0049 15.3 11.1 1.0 1 0 0 1 1 1 1 Hsp90 protein BRF1 PF07741.8 EGC30848.1 - 0.0041 17.3 11.3 0.005 17.0 7.9 1.2 1 0 0 1 1 1 1 Brf1-like TBP-binding domain Secretin_N_2 PF07655.8 EGC30848.1 - 0.0058 16.9 12.6 0.0058 16.9 8.8 1.5 1 1 1 2 2 2 1 Secretin N-terminal domain HABP4_PAI-RBP1 PF04774.10 EGC30848.1 - 0.018 15.5 11.3 0.022 15.2 7.9 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family SPX PF03105.14 EGC30848.1 - 0.093 12.4 16.4 0.12 12.1 11.4 1.1 1 0 0 1 1 1 0 SPX domain Host_attach PF10116.4 EGC30848.1 - 0.099 12.8 0.7 0.11 12.7 0.5 1.1 1 0 0 1 1 1 0 Protein required for attachment to host cells Eapp_C PF10238.4 EGC30848.1 - 0.23 11.3 16.3 0.3 11.0 11.3 1.3 1 0 0 1 1 1 0 E2F-associated phosphoprotein Pex14_N PF04695.8 EGC30848.1 - 0.25 11.3 6.8 0.27 11.2 4.7 1.1 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF3408 PF11888.3 EGC30848.1 - 0.27 11.1 5.9 0.32 10.9 4.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3408) POX PF07526.6 EGC30848.1 - 0.27 11.4 6.6 0.34 11.1 4.6 1.3 1 0 0 1 1 1 0 Associated with HOX NST1 PF13945.1 EGC30848.1 - 0.28 11.2 13.3 0.35 10.9 9.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator Striatin PF08232.7 EGC30848.1 - 0.38 11.0 9.1 0.44 10.8 6.3 1.1 1 0 0 1 1 1 0 Striatin family DUF2413 PF10310.4 EGC30848.1 - 0.49 9.1 11.4 0.56 8.9 7.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) NARP1 PF12569.3 EGC30848.1 - 0.74 8.5 9.8 0.8 8.3 6.8 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Tim54 PF11711.3 EGC30848.1 - 0.98 7.9 10.5 1.1 7.7 7.3 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Spore_coat_CotO PF14153.1 EGC30848.1 - 1 8.8 12.7 1.2 8.5 8.8 1.1 1 0 0 1 1 1 0 Spore coat protein CotO Sec62 PF03839.11 EGC30848.1 - 1 8.7 13.3 1.2 8.4 9.2 1.0 1 0 0 1 1 1 0 Translocation protein Sec62 Neur_chan_memb PF02932.11 EGC30848.1 - 1.4 8.7 5.5 1.6 8.6 3.8 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF763 PF05559.6 EGC30848.1 - 1.5 7.6 5.6 1.8 7.4 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Gti1_Pac2 PF09729.4 EGC30848.1 - 2 8.2 7.6 2.1 8.2 5.2 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Tom22 PF04281.8 EGC30848.1 - 2.2 7.8 4.8 2.9 7.4 3.3 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 PDCD2_C PF04194.8 EGC30848.1 - 2.3 7.7 8.1 2.9 7.4 5.6 1.1 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain SUZ PF12752.2 EGC30848.1 - 2.6 8.6 7.1 6.3 7.3 4.9 1.8 1 1 0 1 1 1 0 SUZ domain DUF3807 PF12720.2 EGC30848.1 - 2.8 8.0 11.9 3.2 7.8 8.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) DUF1441 PF07278.6 EGC30848.1 - 3.1 7.4 7.5 1.1 8.9 0.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF1441) Folate_carrier PF01770.13 EGC30848.1 - 4.3 5.7 4.9 4.2 5.7 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier GCD14 PF08704.5 EGC30848.1 - 5.6 6.3 7.5 5.9 6.3 5.2 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Serinc PF03348.10 EGC30848.1 - 6.2 5.4 5.9 6.4 5.3 4.1 1.0 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2660 PF10859.3 EGC30848.1 - 9 6.5 14.9 0.99 9.6 6.2 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2660) Arrestin_C PF02752.17 EGC30848.1 - 9.1 6.3 12.2 12 6.0 8.5 1.2 1 0 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain 60KD_IMP PF02096.15 EGC30849.1 - 1.1e-30 106.7 2.5 2.2e-30 105.8 1.7 1.4 1 0 0 1 1 1 1 60Kd inner membrane protein Tox-REase-7 PF15649.1 EGC30849.1 - 0.022 14.8 0.9 0.022 14.8 0.6 2.0 2 0 0 2 2 2 0 Restriction endonuclease fold toxin 7 PCI PF01399.22 EGC30850.1 - 3.3e-17 62.7 0.8 3.4e-16 59.4 0.5 2.6 2 0 0 2 2 2 1 PCI domain RPN7 PF10602.4 EGC30850.1 - 0.028 13.8 0.2 0.17 11.2 0.0 2.4 2 1 1 3 3 3 0 26S proteasome subunit RPN7 DUF2299 PF10061.4 EGC30851.1 - 0.0091 15.4 0.1 0.018 14.4 0.1 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2299) DUF966 PF06136.8 EGC30851.1 - 5.6 6.2 36.8 0.12 11.7 11.0 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF966) PI3_PI4_kinase PF00454.22 EGC30852.1 - 9.4e-08 31.8 6.5 0.00076 19.0 0.2 3.9 2 1 0 3 3 3 3 Phosphatidylinositol 3- and 4-kinase ABC2_membrane PF01061.19 EGC30853.1 - 6.2e-39 133.3 25.1 6.2e-39 133.3 17.4 2.2 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC30853.1 - 1.5e-25 90.1 0.0 4.1e-25 88.6 0.0 1.8 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC30853.1 - 6.7e-05 22.9 0.1 6.7e-05 22.9 0.0 4.0 3 1 1 4 4 4 2 AAA domain AAA_25 PF13481.1 EGC30853.1 - 0.013 14.8 0.4 0.027 13.8 0.0 1.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 EGC30853.1 - 0.02 13.7 10.5 0.054 12.3 7.3 1.7 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF258 PF03193.11 EGC30853.1 - 0.021 14.0 0.0 0.043 12.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGC30853.1 - 0.082 12.8 0.2 0.38 10.6 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Ribosomal_L18_c PF14204.1 EGC30853.1 - 2.7 8.6 7.1 24 5.5 3.2 2.3 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Laminin_EGF PF00053.19 EGC30853.1 - 4.6 7.2 23.4 0.16 11.9 4.4 3.4 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Serglycin PF04360.7 EGC30854.1 - 0.0028 17.4 5.0 0.0028 17.4 3.5 2.4 2 1 1 3 3 3 1 Serglycin Proteasome PF00227.21 EGC30855.1 - 9.3e-64 214.2 0.0 1.1e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC30855.1 - 1.2e-13 50.1 0.4 2.6e-13 49.0 0.3 1.6 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Pet191_N PF10203.4 EGC30856.1 - 4.4e-18 65.0 3.1 6.8e-18 64.4 2.2 1.3 1 0 0 1 1 1 1 Cytochrome c oxidase assembly protein PET191 CHCH PF06747.8 EGC30856.1 - 0.0059 16.4 5.8 0.029 14.3 0.8 2.8 2 0 0 2 2 2 1 CHCH domain HGTP_anticodon2 PF12745.2 EGC30856.1 - 0.062 12.4 3.4 0.075 12.1 2.3 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs DUF1903 PF08991.5 EGC30856.1 - 0.2 11.8 4.7 0.079 13.1 1.3 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF1903) Fil_haemagg PF05594.9 EGC30858.1 - 0.0018 18.5 1.6 0.0018 18.5 1.1 5.2 5 3 0 5 5 5 2 Haemagluttinin repeat PP2C PF00481.16 EGC30859.1 - 2.6e-49 167.9 0.1 2.6e-49 167.9 0.1 2.6 2 1 1 3 3 3 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGC30859.1 - 3.5e-05 23.2 0.5 0.00012 21.6 0.0 2.1 2 1 0 2 2 2 1 Protein phosphatase 2C SpoIIE PF07228.7 EGC30859.1 - 9.8e-05 22.1 0.0 0.064 12.9 0.0 2.3 2 0 0 2 2 2 2 Stage II sporulation protein E (SpoIIE) DUF3166 PF11365.3 EGC30859.1 - 0.0055 17.1 7.4 0.018 15.5 0.0 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF3166) zf-C4H2 PF10146.4 EGC30859.1 - 0.0078 16.2 10.7 0.0078 16.2 7.4 3.1 2 1 1 3 3 3 1 Zinc finger-containing protein V_ATPase_I PF01496.14 EGC30859.1 - 0.019 12.8 18.6 0.024 12.5 4.4 2.6 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family COG5 PF10392.4 EGC30859.1 - 0.49 10.3 20.8 0.19 11.6 5.5 2.7 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF3450 PF11932.3 EGC30859.1 - 0.88 8.7 22.3 3.6 6.7 6.8 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) IncA PF04156.9 EGC30859.1 - 2.6 7.5 33.0 2.9 7.4 8.7 2.7 1 1 1 2 2 2 0 IncA protein GCV_H PF01597.14 EGC30862.1 - 3.4e-16 59.0 1.6 8.7e-16 57.7 1.1 1.6 1 1 0 1 1 1 1 Glycine cleavage H-protein RnfC_N PF13375.1 EGC30862.1 - 0.032 13.9 0.0 0.057 13.1 0.0 1.4 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain NQRA PF05896.6 EGC30862.1 - 0.043 13.0 0.0 0.047 12.8 0.0 1.2 1 0 0 1 1 1 0 Na(+)-translocating NADH-quinone reductase subunit A (NQRA) Semialdhyde_dhC PF02774.13 EGC30862.1 - 0.11 12.3 0.0 0.23 11.3 0.0 1.4 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, dimerisation domain Tubulin PF00091.20 EGC30863.1 - 1.2e-70 237.7 0.0 1.8e-70 237.1 0.0 1.3 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGC30863.1 - 3e-46 156.5 0.8 4.8e-46 155.9 0.6 1.3 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGC30863.1 - 0.0086 15.5 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 Tubulin domain Peptidase_C1 PF00112.18 EGC30864.1 - 5.3e-73 245.5 6.2 6.3e-73 245.2 4.3 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EGC30864.1 - 2.6e-06 26.2 0.9 0.00014 20.5 0.2 2.1 2 0 0 2 2 2 2 Peptidase C1-like family ydhR PF08803.6 EGC30864.1 - 0.13 12.3 0.0 0.24 11.4 0.0 1.4 1 0 0 1 1 1 0 Putative mono-oxygenase ydhR Cytokin_check_N PF10407.4 EGC30865.1 - 0.44 10.2 8.8 0.26 10.9 0.7 3.0 3 0 0 3 3 3 0 Cdc14 phosphatase binding protein N-terminus SH2 PF00017.19 EGC30866.1 - 3.9e-08 32.9 0.0 8.6e-08 31.8 0.0 1.5 1 0 0 1 1 1 1 SH2 domain Neuregulin PF02158.10 EGC30866.1 - 0.065 12.0 0.1 0.59 8.8 0.0 2.0 2 0 0 2 2 2 0 Neuregulin family XAP5 PF04921.9 EGC30867.1 - 0.021 14.4 1.7 0.023 14.2 1.2 1.0 1 0 0 1 1 1 0 XAP5, circadian clock regulator Radial_spoke_3 PF06098.6 EGC30867.1 - 1.9 7.3 7.4 1.9 7.4 5.1 1.0 1 0 0 1 1 1 0 Radial spoke protein 3 CCDC66 PF15236.1 EGC30867.1 - 2.2 7.8 15.0 2.5 7.6 10.4 1.1 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 66 Prp19_bind PF06991.6 EGC30867.1 - 5.3 6.2 10.1 5.9 6.0 7.0 1.1 1 0 0 1 1 1 0 Splicing factor, Prp19-binding domain GST_N_3 PF13417.1 EGC30869.1 - 1.6e-09 37.8 0.0 3.9e-09 36.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC30869.1 - 3.2e-09 36.6 0.0 9.3e-09 35.1 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC30869.1 - 9.8e-09 35.0 0.1 1.9e-08 34.1 0.0 1.6 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC30869.1 - 2.7e-06 27.7 0.0 3.8e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGC30869.1 - 5.2e-06 26.5 0.1 3.2e-05 23.9 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC30869.1 - 0.0047 16.7 0.0 0.007 16.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC30870.1 - 2.7e-11 43.5 0.0 5e-11 42.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC30870.1 - 1.1e-09 38.1 0.1 1.9e-09 37.3 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC30870.1 - 1.6e-09 37.6 0.0 3.1e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC30870.1 - 1.6e-06 28.1 0.0 3.3e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC30870.1 - 2.3e-06 28.0 0.0 3.3e-06 27.4 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC30870.1 - 0.003 17.3 0.0 0.0059 16.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF676 PF05057.9 EGC30870.1 - 0.069 12.4 0.0 0.11 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) RNase_T PF00929.19 EGC30870.1 - 0.13 12.5 0.6 5.2 7.3 0.1 2.2 1 1 1 2 2 2 0 Exonuclease GST_N_3 PF13417.1 EGC30871.1 - 3e-10 40.1 0.0 7.9e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC30871.1 - 2.1e-09 37.2 0.0 5.4e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC30871.1 - 3.9e-08 33.1 0.0 7.3e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGC30871.1 - 6.9e-08 32.5 0.0 2.2e-07 30.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC30871.1 - 7.1e-07 29.6 0.0 1.3e-06 28.7 0.0 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC30871.1 - 0.00088 19.1 0.0 0.0016 18.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC30872.1 - 1e-10 41.4 0.1 1.6e-10 40.7 0.1 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC30872.1 - 1.7e-09 37.5 0.0 3.3e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC30872.1 - 1e-08 35.2 0.0 1.6e-08 34.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC30872.1 - 4.8e-08 33.3 0.0 7.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGC30872.1 - 1.1e-07 31.9 0.0 2.2e-07 30.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC30872.1 - 0.0001 22.0 0.0 0.00017 21.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ADH_zinc_N PF00107.21 EGC30873.1 - 2.1e-26 91.9 0.0 4.2e-26 91.0 0.0 1.5 1 1 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC30873.1 - 1.1e-08 34.8 0.0 5.3e-07 29.3 0.0 3.1 3 1 1 4 4 4 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC30873.1 - 6.3e-06 27.1 0.0 3.1e-05 24.8 0.0 2.1 2 0 0 2 2 2 1 Zinc-binding dehydrogenase GTP_EFTU_D2 PF03144.20 EGC30873.1 - 0.00075 19.5 0.0 0.018 15.1 0.0 2.6 2 0 0 2 2 2 1 Elongation factor Tu domain 2 TrkA_N PF02254.13 EGC30873.1 - 0.022 14.7 0.1 0.046 13.7 0.1 1.6 1 0 0 1 1 1 0 TrkA-N domain AlaDh_PNT_C PF01262.16 EGC30873.1 - 0.023 14.2 0.1 0.044 13.3 0.0 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DUF2577 PF10844.3 EGC30873.1 - 0.07 13.1 0.0 2.5 8.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2577) PK_C PF02887.11 EGC30873.1 - 0.084 12.4 0.2 0.85 9.1 0.0 2.3 1 1 1 2 2 2 0 Pyruvate kinase, alpha/beta domain zf-RING_2 PF13639.1 EGC30874.1 - 2.2e-11 43.4 6.8 3.7e-11 42.6 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC30874.1 - 6.8e-10 38.4 8.8 1.1e-09 37.7 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC30874.1 - 2.2e-08 33.9 11.1 4e-08 33.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC30874.1 - 2.5e-08 33.4 12.0 4.7e-08 32.5 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC30874.1 - 1e-07 31.5 10.1 1.9e-07 30.6 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC30874.1 - 3.4e-05 23.8 4.7 8e-05 22.6 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC30874.1 - 0.00011 21.9 10.1 0.00027 20.7 7.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC30874.1 - 0.002 17.6 8.8 0.0043 16.6 6.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC30874.1 - 0.0046 16.6 4.6 0.0065 16.1 2.2 2.0 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGC30874.1 - 0.0061 16.3 3.6 0.016 15.0 2.5 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CAF-1_p150 PF11600.3 EGC30874.1 - 0.02 14.2 45.3 0.078 12.3 26.1 2.1 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_6 PF14835.1 EGC30874.1 - 0.025 14.3 2.8 0.051 13.3 1.9 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein N6_N4_Mtase PF01555.13 EGC30874.1 - 0.37 10.2 6.3 0.28 10.6 0.1 2.4 2 1 0 2 2 2 0 DNA methylase Prok-RING_4 PF14447.1 EGC30874.1 - 3.1 7.4 6.6 32 4.1 4.6 2.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Phage_Coat_A PF05357.8 EGC30875.1 - 0.0027 17.2 0.8 0.38 10.3 0.0 3.4 2 1 0 2 2 2 2 Phage Coat Protein A MFS_1 PF07690.11 EGC30876.1 - 7.3e-40 136.7 53.5 6.3e-29 100.7 17.7 2.5 2 1 1 3 3 3 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC30876.1 - 4.9e-12 45.1 32.3 4.4e-07 28.8 5.8 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EGC30876.1 - 2.5e-06 26.1 24.8 0.00013 20.4 3.0 2.6 3 0 0 3 3 3 2 MFS/sugar transport protein MFS_1_like PF12832.2 EGC30876.1 - 0.55 10.0 10.5 0.94 9.3 0.1 3.3 4 0 0 4 4 4 0 MFS_1 like family MCPVI PF02993.9 EGC30877.1 - 2.8 8.0 10.0 4.3 7.4 6.9 1.2 1 0 0 1 1 1 0 Minor capsid protein VI Pkinase_Tyr PF07714.12 EGC30878.1 - 1.2e-61 208.1 0.0 1.7e-61 207.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30878.1 - 1.9e-51 174.7 0.4 1.4e-50 171.8 0.0 2.4 2 1 0 2 2 2 1 Protein kinase domain WD40 PF00400.27 EGC30878.1 - 5.1e-15 54.7 10.2 1e-06 28.3 0.5 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat FNIP PF05725.7 EGC30879.1 - 3e-71 235.1 53.0 4.7e-16 58.4 0.6 9.8 7 2 2 10 10 10 9 FNIP Repeat LRR_5 PF13306.1 EGC30879.1 - 0.023 14.3 4.4 0.36 10.5 0.0 3.0 2 1 1 3 3 3 0 Leucine rich repeats (6 copies) Pro-kuma_activ PF09286.6 EGC30880.1 - 1.6e-33 115.7 0.0 2.5e-33 115.1 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC30880.1 - 0.00077 18.7 0.3 0.0016 17.6 0.2 1.5 1 1 0 1 1 1 1 Subtilase family Zip PF02535.17 EGC30881.1 - 0.0086 15.1 0.8 0.0086 15.1 0.5 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter FNIP PF05725.7 EGC30882.1 - 1.4e-123 402.6 60.4 1.5e-16 60.0 0.3 11.6 6 3 8 14 14 14 14 FNIP Repeat DUF3215 PF11503.3 EGC30882.1 - 0.023 14.2 0.2 1.4 8.5 0.0 3.7 5 0 0 5 5 5 0 Protein of unknown function (DUF3215) DUF1769 PF08588.5 EGC30882.1 - 0.32 10.9 23.0 15 5.6 0.1 9.2 3 3 10 13 13 13 0 Protein of unknown function (DUF1769) Caenor_Her-1 PF09232.5 EGC30883.1 - 0.017 15.1 0.0 0.036 14.1 0.0 1.6 1 0 0 1 1 1 0 Caenorhabditis elegans Her-1 DUF3408 PF11888.3 EGC30883.1 - 1.9 8.4 8.2 21 5.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3408) Prefoldin PF02996.12 EGC30884.1 - 6.6e-19 67.7 4.0 6.6e-19 67.7 2.8 1.7 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_2 PF01920.15 EGC30884.1 - 0.00044 19.9 3.8 0.00044 19.9 2.6 2.7 1 1 2 3 3 3 1 Prefoldin subunit MscS_porin PF12795.2 EGC30884.1 - 0.0084 15.4 0.2 0.0084 15.4 0.1 2.0 2 1 0 2 2 2 1 Mechanosensitive ion channel porin domain Prefoldin_3 PF13758.1 EGC30884.1 - 0.0097 15.6 1.7 0.024 14.3 1.1 1.7 1 1 0 1 1 1 1 Prefoldin subunit Mnd1 PF03962.10 EGC30884.1 - 0.023 14.3 4.4 0.45 10.1 0.0 2.1 2 0 0 2 2 2 0 Mnd1 family FliD_C PF07195.7 EGC30884.1 - 0.045 13.0 1.4 0.075 12.3 0.7 1.6 1 1 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus Flagellin_C PF00700.16 EGC30884.1 - 0.099 12.8 2.2 0.18 12.0 0.1 2.3 2 1 1 3 3 3 0 Bacterial flagellin C-terminal helical region DUF4463 PF14703.1 EGC30884.1 - 0.27 11.7 5.7 0.81 10.2 0.2 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) Cortex-I_coil PF09304.5 EGC30884.1 - 2.5 8.1 12.6 3 7.9 0.2 2.1 2 0 0 2 2 2 0 Cortexillin I, coiled coil FlaC_arch PF05377.6 EGC30884.1 - 2.8 7.9 11.3 0.26 11.1 0.3 3.1 2 1 0 2 2 2 0 Flagella accessory protein C (FlaC) IncA PF04156.9 EGC30884.1 - 4.6 6.7 8.4 8.9 5.8 0.0 2.2 2 0 0 2 2 2 0 IncA protein LysM PF01476.15 EGC30885.1 - 0.0019 18.0 0.1 0.011 15.6 0.0 2.2 2 0 0 2 2 2 1 LysM domain DUF4199 PF13858.1 EGC30885.1 - 0.16 11.9 1.0 0.18 11.7 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) ARD PF03079.9 EGC30885.1 - 0.8 9.6 5.8 0.52 10.2 1.0 2.1 2 0 0 2 2 2 0 ARD/ARD' family PRP21_like_P PF12230.3 EGC30885.1 - 2.9 7.3 11.9 0.89 9.0 2.8 2.1 2 0 0 2 2 2 0 Pre-mRNA splicing factor PRP21 like protein HTH_24 PF13412.1 EGC30886.1 - 0.087 12.2 0.2 15 5.0 0.0 2.4 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Ribosomal_60s PF00428.14 EGC30887.1 - 1.8e-27 95.5 15.8 3.8e-27 94.4 11.0 1.6 1 0 0 1 1 1 1 60s Acidic ribosomal protein Prok-RING_4 PF14447.1 EGC30887.1 - 0.11 12.0 0.1 0.19 11.2 0.1 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3015 PF11220.3 EGC30888.1 - 0.095 12.2 0.0 0.23 11.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3015) Rhomboid PF01694.17 EGC30889.1 - 4.3e-20 72.2 13.7 9.9e-20 71.0 9.5 1.6 1 1 0 1 1 1 1 Rhomboid family G-7-MTase PF12803.2 EGC30889.1 - 0.27 10.3 6.6 0.4 9.7 4.6 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF3216 PF11505.3 EGC30890.1 - 0.17 11.7 0.1 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) V_ATPase_I PF01496.14 EGC30890.1 - 2.4 5.9 14.2 3.6 5.3 9.9 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF3439 PF11921.3 EGC30890.1 - 3.4 7.4 11.2 0.6 9.8 4.9 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3439) His_Phos_2 PF00328.17 EGC30892.1 - 1.6e-21 77.0 0.0 2.2e-21 76.5 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Cyclin_N PF00134.18 EGC30893.1 - 0.012 15.1 0.5 0.012 15.1 0.3 1.7 2 1 0 2 2 2 0 Cyclin, N-terminal domain BSD PF03909.12 EGC30894.1 - 9.7e-20 70.0 9.5 2e-12 46.6 0.1 3.8 3 1 0 3 3 3 2 BSD domain TFIIH_BTF_p62_N PF08567.6 EGC30894.1 - 2.8e-13 49.3 0.1 6.3e-13 48.1 0.1 1.7 1 0 0 1 1 1 1 TFIIH p62 subunit, N-terminal domain Vps36_ESCRT-II PF11605.3 EGC30894.1 - 0.026 14.3 2.2 0.055 13.2 0.1 2.6 2 0 0 2 2 2 0 Vacuolar protein sorting protein 36 Vps36 EMP70 PF02990.11 EGC30895.1 - 7.4e-189 628.5 8.8 1e-188 628.1 6.1 1.2 1 0 0 1 1 1 1 Endomembrane protein 70 DUF3154 PF11351.3 EGC30895.1 - 0.24 11.1 1.7 4.6 7.0 0.2 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3154) Abhydrolase_6 PF12697.2 EGC30896.1 - 1.9e-14 54.1 0.0 3.1e-14 53.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC30896.1 - 7.2e-09 35.5 0.0 1.4e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold RR_TM4-6 PF06459.7 EGC30896.1 - 0.042 13.7 7.3 0.079 12.8 5.1 1.5 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DUF106 PF01956.11 EGC30896.1 - 0.14 11.6 1.8 0.38 10.2 0.7 2.1 2 0 0 2 2 2 0 Integral membrane protein DUF106 CDC45 PF02724.9 EGC30896.1 - 0.21 9.5 6.0 0.036 12.1 1.6 1.5 2 0 0 2 2 2 0 CDC45-like protein Zip PF02535.17 EGC30896.1 - 0.48 9.3 27.4 0.39 9.6 1.5 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter BSMAP PF12280.3 EGC30896.1 - 1.8 8.4 4.1 1.1 9.0 1.5 1.6 2 0 0 2 2 2 0 Brain specific membrane anchored protein Sec62 PF03839.11 EGC30896.1 - 5.6 6.3 12.3 13 5.1 8.5 1.6 1 0 0 1 1 1 0 Translocation protein Sec62 Transket_pyr PF02779.19 EGC30897.1 - 4.6e-46 156.5 0.0 6.6e-46 156.0 0.0 1.2 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain Transketolase_C PF02780.15 EGC30897.1 - 5.7e-39 132.8 0.0 3.9e-38 130.1 0.0 2.2 2 0 0 2 2 2 1 Transketolase, C-terminal domain PARP PF00644.15 EGC30900.1 - 3.9e-36 124.4 1.7 2.9e-33 115.0 0.1 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC30900.1 - 8.8e-12 44.8 5.6 4e-11 42.7 3.9 2.2 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain BRCT PF00533.21 EGC30900.1 - 1.5e-06 28.2 0.8 7.2e-06 26.0 0.6 2.3 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain EcsB PF05975.7 EGC30900.1 - 0.19 10.1 0.5 0.29 9.5 0.3 1.2 1 0 0 1 1 1 0 Bacterial ABC transporter protein EcsB Response_reg PF00072.19 EGC30901.1 - 3.5e-21 75.2 0.1 5.9e-21 74.5 0.0 1.4 1 0 0 1 1 1 1 Response regulator receiver domain DUF3188 PF11384.3 EGC30902.1 - 0.024 14.1 1.1 0.034 13.7 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) EamA PF00892.15 EGC30903.1 - 1.3e-07 31.6 10.1 3.4e-07 30.3 7.1 1.7 1 1 0 1 1 1 1 EamA-like transporter family EmrE PF13536.1 EGC30903.1 - 1.6e-06 28.2 7.1 1.2e-05 25.4 5.4 1.9 1 1 1 2 2 2 1 Multidrug resistance efflux transporter UPF0546 PF10639.4 EGC30903.1 - 0.002 17.9 0.3 0.002 17.9 0.2 2.1 1 1 1 2 2 2 1 Uncharacterised protein family UPF0546 TPT PF03151.11 EGC30903.1 - 0.0034 17.0 8.7 0.0036 16.9 1.7 2.1 1 1 0 2 2 2 1 Triose-phosphate Transporter family DUF3671 PF12420.3 EGC30903.1 - 0.01 15.7 2.3 0.01 15.7 1.6 2.4 2 1 0 2 2 2 0 Protein of unknown function UAA PF08449.6 EGC30903.1 - 0.064 12.1 7.9 0.11 11.4 5.5 1.5 1 1 0 1 1 1 0 UAA transporter family DUF543 PF04418.7 EGC30903.1 - 0.23 11.4 3.3 5 7.1 0.4 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF543) Multi_Drug_Res PF00893.14 EGC30903.1 - 0.26 11.7 5.2 0.49 10.9 3.4 1.6 1 1 0 1 1 1 0 Small Multidrug Resistance protein DUF485 PF04341.7 EGC30903.1 - 2.8 7.7 6.9 0.58 9.9 0.6 2.1 1 1 1 2 2 2 0 Protein of unknown function, DUF485 Hist_deacetyl PF00850.14 EGC30904.1 - 3e-78 263.2 0.1 3e-78 263.2 0.1 1.4 2 0 0 2 2 2 1 Histone deacetylase domain FNIP PF05725.7 EGC30905.1 - 1.9e-16 59.6 30.6 6.8e-07 29.1 0.4 5.5 5 1 1 6 6 6 4 FNIP Repeat Zip PF02535.17 EGC30905.1 - 4.1e-08 32.6 1.5 6.1e-08 32.0 1.1 1.2 1 0 0 1 1 1 1 ZIP Zinc transporter zf-B_box PF00643.19 EGC30905.1 - 1.7e-05 24.5 5.3 3.1e-05 23.7 3.6 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC30905.1 - 0.03 14.0 3.2 0.06 13.0 2.2 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1644 PF07800.7 EGC30905.1 - 0.93 9.3 5.0 2.9 7.7 3.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) FNIP PF05725.7 EGC30906.1 - 7e-17 61.1 16.6 0.00028 20.7 0.1 5.8 4 1 0 5 5 5 4 FNIP Repeat zf-B_box PF00643.19 EGC30906.1 - 4.3e-05 23.3 3.8 7.8e-05 22.4 2.6 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC30906.1 - 0.049 13.3 2.0 0.094 12.4 1.4 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF1644 PF07800.7 EGC30906.1 - 5 6.9 6.5 14 5.4 4.5 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Zip PF02535.17 EGC30907.1 - 9.3e-37 126.7 11.5 1.2e-36 126.3 8.0 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter Kinocilin PF15033.1 EGC30907.1 - 0.096 12.2 0.3 0.31 10.5 0.0 2.0 2 0 0 2 2 2 0 Kinocilin protein PAP2 PF01569.16 EGC30907.1 - 1.4 8.6 4.6 0.47 10.1 0.7 2.0 2 1 0 2 2 2 0 PAP2 superfamily FNIP PF05725.7 EGC30908.1 - 1.3e-10 41.0 19.9 1e-05 25.3 0.4 3.7 1 1 3 4 4 4 4 FNIP Repeat DUF3835 PF12927.2 EGC30909.1 - 0.054 14.4 2.2 0.1 13.5 1.5 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3835) RED_N PF07808.8 EGC30909.1 - 0.075 12.2 8.4 0.1 11.7 5.8 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Mucin PF01456.12 EGC30909.1 - 0.15 11.8 15.4 0.23 11.2 10.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Med15 PF09606.5 EGC30909.1 - 9.6 4.2 31.9 11 4.0 22.1 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SWIB PF02201.13 EGC30910.1 - 3.7e-14 52.1 0.2 6.9e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 SWIB/MDM2 domain DOT1 PF08123.8 EGC30910.1 - 0.00048 19.5 0.4 0.00098 18.4 0.1 1.6 2 0 0 2 2 2 1 Histone methylation protein DOT1 GerPC PF10737.4 EGC30910.1 - 0.0043 16.8 1.9 0.41 10.3 0.1 3.0 2 1 1 3 3 3 2 Spore germination protein GerPC GidB PF02527.10 EGC30910.1 - 0.061 12.4 0.9 0.19 10.8 0.1 2.1 2 0 0 2 2 2 0 rRNA small subunit methyltransferase G DUF1564 PF07600.6 EGC30910.1 - 0.063 12.6 3.8 1.3 8.2 0.1 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1564) ketoacyl-synt PF00109.21 EGC30911.1 - 5.3e-63 212.8 0.0 8.2e-63 212.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EGC30911.1 - 6.3e-43 146.4 0.0 1.3e-42 145.4 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC30911.1 - 6.8e-42 143.9 0.0 1.3e-41 143.0 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC30911.1 - 8.9e-29 99.7 0.0 5e-28 97.3 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC30911.1 - 2.6e-24 85.8 0.0 2.2e-23 82.8 0.0 2.2 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGC30911.1 - 1.8e-20 73.2 0.0 2.9e-20 72.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC30911.1 - 2e-17 63.6 0.0 2.9e-15 56.5 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EGC30911.1 - 9.3e-17 61.3 3.7 3.3e-16 59.5 0.0 3.5 3 0 0 3 3 2 1 Methyltransferase domain Epimerase PF01370.16 EGC30911.1 - 2e-10 40.4 0.0 2.2e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC30911.1 - 3.2e-08 34.5 0.0 8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC30911.1 - 3.3e-08 33.4 0.0 8.4e-08 32.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGC30911.1 - 2.9e-07 30.2 0.1 6.4e-07 29.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EGC30911.1 - 8.3e-06 26.3 0.0 4.5e-05 23.9 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC30911.1 - 2e-05 25.0 0.0 6.8e-05 23.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC30911.1 - 0.00015 21.9 0.1 0.00043 20.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC30911.1 - 0.00043 19.3 0.0 0.001 18.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC30912.1 - 5.3e-62 209.5 0.0 8.3e-62 208.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC30912.1 - 3.8e-43 148.0 0.0 7e-43 147.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC30912.1 - 2.5e-40 137.9 0.0 5.5e-40 136.8 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC30912.1 - 1.5e-29 102.2 0.0 4.1e-29 100.8 0.0 1.8 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC30912.1 - 7.7e-25 87.5 0.0 5.9e-24 84.7 0.0 2.1 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGC30912.1 - 2e-21 76.4 0.0 3.2e-21 75.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC30912.1 - 8.1e-18 64.8 0.0 9.3e-16 58.1 0.0 2.4 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EGC30912.1 - 7.4e-17 61.6 3.3 7.3e-16 58.4 0.0 3.7 3 0 0 3 3 2 1 Methyltransferase domain Epimerase PF01370.16 EGC30912.1 - 8.7e-10 38.4 0.1 2.1e-05 24.0 0.0 3.0 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family Methyltransf_23 PF13489.1 EGC30912.1 - 1.1e-08 34.9 0.0 2.8e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC30912.1 - 3.2e-08 34.5 0.0 8e-08 33.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC30912.1 - 3.8e-07 29.8 0.1 8.6e-07 28.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC30912.1 - 7.8e-05 23.0 0.0 0.00026 21.4 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30912.1 - 0.00011 22.7 0.0 0.0005 20.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC30912.1 - 0.00017 21.8 0.1 0.00043 20.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC30912.1 - 0.00027 20.0 0.0 0.00061 18.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Pkinase PF00069.20 EGC30913.1 - 8.5e-77 257.7 1.1 1e-76 257.5 0.0 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30913.1 - 1.2e-33 116.2 0.0 5.7e-33 114.0 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC30913.1 - 0.0016 17.5 0.0 0.46 9.3 0.0 2.3 2 0 0 2 2 2 2 Kinase-like Orbi_VP5 PF00901.12 EGC30914.1 - 7 4.7 21.9 0.94 7.6 3.1 2.4 2 0 0 2 2 2 0 Orbivirus outer capsid protein VP5 WD40 PF00400.27 EGC30916.1 - 3.5e-38 128.1 14.4 6.5e-09 35.3 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC30916.1 - 1.7e-07 30.9 4.0 0.00052 19.7 0.1 5.0 3 2 2 5 5 5 2 Ciliary BBSome complex subunit 2, middle region F-box PF00646.28 EGC30916.1 - 0.002 17.7 0.8 0.29 10.8 0.0 2.8 2 0 0 2 2 2 2 F-box domain F-box-like PF12937.2 EGC30916.1 - 0.0031 17.2 0.0 0.007 16.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like PQQ_2 PF13360.1 EGC30916.1 - 0.036 13.5 0.2 2.3 7.6 0.0 2.3 2 0 0 2 2 2 0 PQQ-like domain Bap31 PF05529.7 EGC30917.1 - 1.2e-26 93.3 9.2 1.6e-26 92.9 6.3 1.2 1 0 0 1 1 1 1 B-cell receptor-associated protein 31-like Hormone_1 PF00103.15 EGC30917.1 - 0.0015 17.8 3.7 0.0015 17.8 2.6 1.5 2 0 0 2 2 2 1 Somatotropin hormone family IncA PF04156.9 EGC30917.1 - 0.0038 16.8 7.4 0.0038 16.8 5.1 1.7 2 0 0 2 2 2 1 IncA protein NABP PF07990.7 EGC30917.1 - 0.013 14.8 5.7 0.018 14.3 4.0 1.2 1 0 0 1 1 1 0 Nucleic acid binding protein NABP DUF972 PF06156.8 EGC30917.1 - 0.037 14.3 12.1 0.088 13.1 8.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF972) Phage_GP20 PF06810.6 EGC30917.1 - 0.26 10.7 19.1 0.42 10.0 13.3 1.3 1 0 0 1 1 1 0 Phage minor structural protein GP20 Seryl_tRNA_N PF02403.17 EGC30917.1 - 0.27 11.2 12.0 0.53 10.3 8.3 1.5 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain SSXT PF05030.7 EGC30917.1 - 0.28 10.7 2.4 0.55 9.8 1.6 1.5 1 0 0 1 1 1 0 SSXT protein (N-terminal region) Swi5 PF07061.6 EGC30917.1 - 0.33 10.7 10.4 0.86 9.4 7.2 1.8 1 1 0 1 1 1 0 Swi5 bZIP_1 PF00170.16 EGC30917.1 - 0.4 10.6 12.9 0.18 11.8 3.2 2.5 1 1 1 2 2 2 0 bZIP transcription factor DUF4446 PF14584.1 EGC30917.1 - 0.53 10.1 11.1 0.057 13.2 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) DUF3043 PF11241.3 EGC30917.1 - 0.55 9.8 0.0 0.55 9.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3043) Speriolin_N PF15058.1 EGC30917.1 - 0.55 10.1 2.8 0.76 9.6 1.9 1.2 1 0 0 1 1 1 0 Speriolin N terminus Spc24 PF08286.6 EGC30917.1 - 0.84 9.3 15.3 0.38 10.4 8.7 1.8 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DivIC PF04977.10 EGC30917.1 - 0.86 9.1 17.1 1 8.8 3.4 3.3 2 1 1 3 3 3 0 Septum formation initiator hDGE_amylase PF14701.1 EGC30917.1 - 1.3 7.7 8.7 1.7 7.4 6.1 1.0 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme DUF342 PF03961.8 EGC30917.1 - 2 6.7 12.9 2.5 6.4 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF641 PF04859.7 EGC30917.1 - 3.2 7.5 12.7 4.9 6.9 8.8 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF641) DUF3430 PF11912.3 EGC30918.1 - 0.0014 18.4 9.5 0.0023 17.7 6.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) Tnp_P_element_C PF12596.3 EGC30918.1 - 0.13 12.6 0.0 0.84 9.9 0.0 2.0 2 0 0 2 2 2 0 87kDa Transposase TatD_DNase PF01026.16 EGC30919.1 - 2.3e-44 151.5 0.1 6.5e-44 150.0 0.0 1.7 2 0 0 2 2 2 1 TatD related DNase DUF2183 PF09949.4 EGC30919.1 - 0.0021 17.9 1.2 0.48 10.3 0.0 3.7 3 1 0 3 3 3 2 Uncharacterized conserved protein (DUF2183) DUF2296 PF10058.4 EGC30919.1 - 0.09 12.5 1.0 7.6 6.3 0.1 2.6 2 0 0 2 2 2 0 Predicted integral membrane metal-binding protein (DUF2296) PT PF04886.7 EGC30920.1 - 0.008 15.4 48.9 0.033 13.5 32.0 2.4 2 1 0 2 2 2 1 PT repeat Fascin PF06268.8 EGC30920.1 - 0.1 12.7 0.8 1 9.4 0.0 2.8 4 0 0 4 4 4 0 Fascin domain CDtoxinA PF03498.9 EGC30920.1 - 0.12 11.7 3.0 0.12 11.7 0.0 2.5 3 0 0 3 3 3 0 Cytolethal distending toxin A/C family DUF4106 PF13388.1 EGC30920.1 - 0.32 9.9 6.5 0.48 9.3 4.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) Trypan_PARP PF05887.6 EGC30920.1 - 0.44 10.3 21.4 0.73 9.6 14.9 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF1371 PF07115.6 EGC30920.1 - 1.5 9.0 8.7 0.086 13.0 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1371) TPR_12 PF13424.1 EGC30921.1 - 1.1e-33 114.9 7.2 8.4e-12 44.8 0.8 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_10 PF13374.1 EGC30921.1 - 5.2e-13 48.4 0.1 0.12 12.3 0.0 5.7 6 0 0 6 6 5 4 Tetratricopeptide repeat NACHT PF05729.7 EGC30921.1 - 6.4e-12 45.4 0.0 6.4e-12 45.4 0.0 2.3 2 0 0 2 2 2 1 NACHT domain TPR_11 PF13414.1 EGC30921.1 - 1.6e-11 43.6 8.6 0.00026 20.5 0.9 4.7 1 1 5 6 6 6 4 TPR repeat TIG PF01833.19 EGC30921.1 - 7.8e-10 38.6 2.0 2.8e-09 36.8 1.4 2.0 1 0 0 1 1 1 1 IPT/TIG domain DUF4062 PF13271.1 EGC30921.1 - 1.2e-08 34.8 0.1 7.6e-08 32.2 0.0 2.5 1 1 0 1 1 1 1 Domain of unknown function (DUF4062) TPR_2 PF07719.12 EGC30921.1 - 3e-08 32.9 10.3 0.23 11.4 0.2 6.3 6 0 0 6 6 6 3 Tetratricopeptide repeat AAA_16 PF13191.1 EGC30921.1 - 2e-07 31.1 6.0 2.6e-06 27.5 0.0 3.6 3 0 0 3 3 3 1 AAA ATPase domain TPR_8 PF13181.1 EGC30921.1 - 2e-06 27.1 8.6 0.035 13.8 0.0 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC30921.1 - 5.9e-06 25.6 13.3 0.29 10.8 0.0 5.7 6 0 0 6 6 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC30921.1 - 1.9e-05 24.1 4.9 1.1 9.2 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat AAA_22 PF13401.1 EGC30921.1 - 0.00038 20.6 0.7 0.0018 18.4 0.0 2.6 2 1 0 2 2 1 1 AAA domain TPR_14 PF13428.1 EGC30921.1 - 0.00055 20.3 0.1 11 6.9 0.0 5.3 5 1 1 6 6 5 0 Tetratricopeptide repeat DUF258 PF03193.11 EGC30921.1 - 0.0042 16.3 0.0 0.013 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 TPR_16 PF13432.1 EGC30921.1 - 0.017 15.8 0.9 2.4 8.9 0.0 3.5 2 1 2 4 4 4 0 Tetratricopeptide repeat AAA_29 PF13555.1 EGC30921.1 - 0.087 12.3 0.0 0.19 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Med15 PF09606.5 EGC30921.1 - 0.87 7.7 50.1 1.3 7.1 34.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal LMBR1 PF04791.11 EGC30922.1 - 2.1e-15 56.2 3.3 2.1e-15 56.2 2.3 2.7 2 1 1 3 3 3 1 LMBR1-like membrane protein IncA PF04156.9 EGC30922.1 - 5.4 6.5 0.0 5.4 6.5 0.0 4.7 4 2 2 6 6 6 0 IncA protein TMEM164 PF14808.1 EGC30923.1 - 4.6e-22 78.4 14.1 5.9e-22 78.0 9.8 1.1 1 0 0 1 1 1 1 TMEM164 family Methyltrans_RNA PF04452.9 EGC30925.1 - 7.5e-42 142.9 1.2 1e-40 139.2 0.9 2.0 1 1 0 1 1 1 1 RNA methyltransferase WD40 PF00400.27 EGC30928.1 - 9.9e-42 139.3 11.7 1.3e-09 37.5 0.0 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGC30928.1 - 4.3e-09 36.3 4.6 0.04 13.6 0.1 4.2 4 1 1 5 5 5 3 Eukaryotic translation initiation factor eIF2A GST_C_3 PF14497.1 EGC30929.1 - 0.045 14.2 0.0 0.17 12.3 0.0 2.0 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain ATG_C PF09333.6 EGC30930.1 - 7.8e-32 109.3 0.1 2.8e-31 107.5 0.1 1.9 1 0 0 1 1 1 1 ATG C terminal domain Chorein_N PF12624.2 EGC30930.1 - 2.5e-09 36.6 0.2 2.2e-08 33.6 0.1 2.8 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter Virul_fac_BrkB PF03631.10 EGC30931.1 - 0.0078 15.6 0.6 0.011 15.1 0.4 1.1 1 0 0 1 1 1 1 Virulence factor BrkB DUF4446 PF14584.1 EGC30931.1 - 0.037 13.8 2.3 0.091 12.5 1.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) Band_3_cyto PF07565.8 EGC30931.1 - 0.15 11.5 9.3 0.012 15.0 2.6 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain TraG_N PF07916.6 EGC30931.1 - 0.23 9.8 2.2 0.32 9.3 1.5 1.1 1 0 0 1 1 1 0 TraG-like protein, N-terminal region DUF2939 PF11159.3 EGC30931.1 - 0.77 9.9 3.6 1.6 8.9 2.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2939) DUF1395 PF07160.7 EGC30931.1 - 3.5 7.0 10.1 6.8 6.1 7.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1395) Neur_chan_memb PF02932.11 EGC30931.1 - 5.7 6.7 9.7 8.6 6.1 6.7 1.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Choline_transpo PF04515.7 EGC30937.1 - 0.014 14.1 0.1 0.015 14.0 0.1 1.1 1 0 0 1 1 1 0 Plasma-membrane choline transporter Ion_trans PF00520.26 EGC30937.1 - 0.071 12.3 4.8 0.067 12.4 2.2 1.6 1 1 1 2 2 2 0 Ion transport protein BRCT PF00533.21 EGC30938.1 - 1.6e-12 47.4 3.4 2e-12 47.0 1.2 2.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC30938.1 - 0.0087 15.8 0.1 0.019 14.8 0.1 1.6 1 0 0 1 1 1 1 twin BRCT domain DUF2681 PF10883.3 EGC30938.1 - 3.6 7.8 9.8 0.86 9.8 2.5 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) bZIP_1 PF00170.16 EGC30938.1 - 6.2 6.8 15.4 0.92 9.5 0.3 4.3 3 1 0 3 3 3 0 bZIP transcription factor DUF912 PF06024.7 EGC30941.1 - 0.14 12.2 6.1 0.22 11.5 4.2 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Claudin_2 PF13903.1 EGC30941.1 - 0.14 11.8 2.2 0.19 11.3 1.5 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction FNIP PF05725.7 EGC30942.1 - 3.8e-150 487.6 82.1 6.9e-15 54.7 1.1 11.4 4 2 7 14 14 14 14 FNIP Repeat Phage_min_tail PF05939.8 EGC30942.1 - 0.00044 20.1 0.0 22 5.0 0.0 5.6 3 2 3 6 6 6 1 Phage minor tail protein MerC PF03203.9 EGC30942.1 - 0.0021 18.4 0.3 83 3.5 0.0 4.8 4 1 1 5 5 5 0 MerC mercury resistance protein Tyr-DNA_phospho PF06087.7 EGC30943.1 - 1.5e-48 165.6 14.0 2.4e-32 112.1 7.6 2.3 2 0 0 2 2 2 2 Tyrosyl-DNA phosphodiesterase Exo_endo_phos PF03372.18 EGC30945.1 - 8.1e-15 55.4 0.1 1.2e-14 54.8 0.1 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family YWFCY PF14293.1 EGC30945.1 - 0.17 11.7 0.8 0.4 10.5 0.6 1.5 1 0 0 1 1 1 0 YWFCY protein DUF3911 PF13050.1 EGC30945.1 - 0.26 11.4 2.4 0.39 10.8 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) Ras PF00071.17 EGC30946.1 - 8.1e-29 100.0 1.0 2.9e-28 98.2 0.7 1.7 1 1 0 1 1 1 1 Ras family Arf PF00025.16 EGC30946.1 - 6.3e-11 41.8 0.6 1.5e-10 40.5 0.1 1.7 2 0 0 2 2 2 1 ADP-ribosylation factor family Miro PF08477.8 EGC30946.1 - 5.6e-07 30.0 0.2 1.8e-05 25.2 0.0 2.6 2 1 1 3 3 3 1 Miro-like protein FNIP PF05725.7 EGC30947.1 - 1.4e-95 312.9 63.1 7.1e-13 48.2 0.2 11.5 8 3 3 12 12 12 11 FNIP Repeat LRR_5 PF13306.1 EGC30947.1 - 0.013 15.1 1.2 6.1 6.5 0.4 3.4 2 2 1 3 3 3 0 Leucine rich repeats (6 copies) Pkinase_Tyr PF07714.12 EGC30948.1 - 1.3e-61 207.9 0.0 1.7e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC30948.1 - 2.6e-61 207.0 0.0 3.7e-61 206.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGC30948.1 - 0.0014 18.4 0.0 0.0039 16.9 0.0 1.6 1 1 1 2 2 2 1 Phosphotransferase enzyme family Mucin PF01456.12 EGC30948.1 - 0.0016 18.1 26.1 0.0016 18.1 18.1 2.5 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3290 PF11694.3 EGC30948.1 - 0.011 15.4 3.2 0.029 14.1 2.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) TMEM154 PF15102.1 EGC30948.1 - 0.014 15.1 0.1 0.014 15.1 0.0 3.7 2 1 1 3 3 3 0 TMEM154 protein family ATP1G1_PLM_MAT8 PF02038.11 EGC30948.1 - 0.028 13.4 0.2 0.077 12.0 0.2 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Sigma_reg_N PF13800.1 EGC30948.1 - 1 9.4 11.7 0.16 11.9 3.1 2.7 2 0 0 2 2 2 0 Sigma factor regulator N-terminal NTP_transf_2 PF01909.18 EGC30949.1 - 4e-06 27.0 1.3 1.4e-05 25.3 0.2 2.5 2 1 0 2 2 2 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 EGC30949.1 - 0.00036 20.3 0.2 0.0011 18.8 0.1 2.0 1 1 0 1 1 1 1 tRNA nucleotidyltransferase, second domain MRP-L27 PF09809.4 EGC30949.1 - 0.0021 17.6 1.0 0.0046 16.5 0.2 1.9 2 0 0 2 2 2 1 Mitochondrial ribosomal protein L27 PAP_assoc PF03828.14 EGC30949.1 - 0.0063 16.4 0.6 0.019 14.9 0.4 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase OAS1_C PF10421.4 EGC30949.1 - 0.007 15.8 0.1 0.019 14.4 0.0 1.7 2 0 0 2 2 2 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus VIT1 PF01988.14 EGC30950.1 - 2.6e-55 187.2 1.5 2.9e-55 187.0 1.0 1.0 1 0 0 1 1 1 1 VIT family UAA PF08449.6 EGC30950.1 - 0.0062 15.4 0.7 0.012 14.5 0.5 1.4 1 0 0 1 1 1 1 UAA transporter family DUF1129 PF06570.6 EGC30950.1 - 0.05 12.9 5.1 0.37 10.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1129) YqbF PF14553.1 EGC30950.1 - 0.089 12.4 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 YqbF, hypothetical protein domain DUF4013 PF13197.1 EGC30950.1 - 2.3 7.5 14.8 0.31 10.3 5.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF4013) Tetraspannin PF00335.15 EGC30950.1 - 4.8 6.3 10.4 23 4.1 7.2 1.9 2 0 0 2 2 2 0 Tetraspanin family RasGEF PF00617.14 EGC30951.1 - 5.4e-50 169.7 0.5 1.5e-49 168.2 0.3 1.7 1 0 0 1 1 1 1 RasGEF domain RhoGAP PF00620.22 EGC30951.1 - 1.3e-11 44.3 4.6 2.7e-11 43.3 1.4 2.4 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.15 EGC30951.1 - 2.4e-09 37.2 2.5 2.4e-09 37.2 1.7 3.2 2 1 1 3 3 3 1 RasGEF N-terminal motif Rsbr_N PF08678.5 EGC30951.1 - 0.034 14.0 0.3 0.034 14.0 0.2 3.2 4 0 0 4 4 4 0 Rsbr N terminal PrmA PF06325.8 EGC30952.1 - 1.5e-10 40.7 0.0 2.5e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) PRMT5 PF05185.11 EGC30952.1 - 3.5e-10 39.3 0.0 5.4e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_11 PF08241.7 EGC30952.1 - 3.8e-09 36.9 0.0 1.3e-08 35.2 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC30952.1 - 1.1e-08 35.6 0.0 2.1e-08 34.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC30952.1 - 2.5e-08 33.4 0.0 4.9e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGC30952.1 - 2.9e-08 33.4 0.1 5.7e-07 29.2 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC30952.1 - 1.6e-06 27.9 0.0 3.7e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC30952.1 - 1.8e-05 25.1 0.0 5e-05 23.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC30952.1 - 1.8e-05 24.7 0.1 4.9e-05 23.3 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGC30952.1 - 0.0002 20.5 0.0 0.00041 19.5 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB FtsJ PF01728.14 EGC30952.1 - 0.0016 18.4 0.0 0.0031 17.5 0.0 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_25 PF13649.1 EGC30952.1 - 0.004 17.4 0.0 0.0094 16.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGC30952.1 - 0.0041 15.8 0.0 0.0078 14.9 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) CaMKII_AD PF08332.5 EGC30952.1 - 0.013 15.4 0.0 0.03 14.1 0.0 1.6 1 0 0 1 1 1 0 Calcium/calmodulin dependent protein kinase II Association Methyltransf_24 PF13578.1 EGC30952.1 - 0.032 15.0 0.0 0.11 13.3 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CMAS PF02353.15 EGC30952.1 - 0.033 13.2 0.0 0.078 12.0 0.0 1.6 1 0 0 1 1 1 0 Mycolic acid cyclopropane synthetase DUF3548 PF12068.3 EGC30952.1 - 0.036 13.3 0.0 0.069 12.4 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3548) Methyltransf_16 PF10294.4 EGC30952.1 - 0.072 12.5 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase PNK3P PF08645.6 EGC30954.1 - 1.1e-50 171.1 0.0 3.1e-50 169.6 0.0 1.8 1 0 0 1 1 1 1 Polynucleotide kinase 3 phosphatase AAA_33 PF13671.1 EGC30954.1 - 7.1e-22 77.8 0.1 3.9e-21 75.4 0.0 2.1 1 1 0 1 1 1 1 AAA domain SAP PF02037.22 EGC30954.1 - 0.00012 21.4 0.0 0.00026 20.4 0.0 1.6 1 0 0 1 1 1 1 SAP domain Zeta_toxin PF06414.7 EGC30954.1 - 0.00027 20.0 3.4 0.046 12.8 0.0 3.0 3 0 0 3 3 3 2 Zeta toxin KTI12 PF08433.5 EGC30954.1 - 0.00068 18.9 12.4 0.001 18.3 2.5 3.0 2 1 0 2 2 2 1 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGC30954.1 - 0.022 15.5 0.5 0.086 13.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain SAPS PF04499.10 EGC30954.1 - 0.05 12.2 6.7 0.063 11.8 4.6 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein DUF966 PF06136.8 EGC30954.1 - 0.058 12.7 9.5 0.091 12.1 6.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Hydrolase_6 PF13344.1 EGC30954.1 - 0.07 13.0 0.8 4.4 7.2 0.0 3.3 3 1 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Nop14 PF04147.7 EGC30954.1 - 0.23 9.3 20.7 0.33 8.8 14.4 1.1 1 0 0 1 1 1 0 Nop14-like family DUF913 PF06025.7 EGC30954.1 - 0.61 8.7 6.6 1.3 7.6 4.6 1.5 1 0 0 1 1 1 0 Domain of Unknown Function (DUF913) DUF2413 PF10310.4 EGC30954.1 - 1.7 7.3 19.2 2.4 6.8 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) CTNNB1_binding PF08347.6 EGC30954.1 - 6.6 6.9 10.1 30 4.7 7.3 1.8 2 0 0 2 2 2 0 N-terminal CTNNB1 binding CDC45 PF02724.9 EGC30954.1 - 6.8 4.6 14.8 9.8 4.0 10.3 1.1 1 0 0 1 1 1 0 CDC45-like protein Ycf1 PF05758.7 EGC30954.1 - 8.3 3.9 11.2 12 3.4 7.8 1.2 1 0 0 1 1 1 0 Ycf1 DDHD PF02862.12 EGC30954.1 - 8.7 6.0 10.4 14 5.3 7.2 1.3 1 0 0 1 1 1 0 DDHD domain Presenilin PF01080.12 EGC30954.1 - 9.1 4.9 7.8 13 4.5 5.4 1.1 1 0 0 1 1 1 0 Presenilin DUF4061 PF13270.1 EGC30955.1 - 0.0084 16.1 3.1 0.0084 16.1 2.1 2.2 1 1 1 2 2 2 2 Domain of unknown function (DUF4061) Glu-tRNAGln PF02686.10 EGC30955.1 - 0.12 12.1 1.0 0.43 10.4 0.1 2.1 2 0 0 2 2 2 0 Glu-tRNAGln amidotransferase C subunit TIG PF01833.19 EGC30957.1 - 8.6e-10 38.4 9.8 6.1e-05 22.9 0.0 3.4 3 0 0 3 3 3 3 IPT/TIG domain DIM PF08194.7 EGC30957.1 - 0.53 10.2 3.8 2.6 8.0 0.2 2.4 2 0 0 2 2 2 0 DIM protein FNIP PF05725.7 EGC30959.1 - 2.7e-55 184.0 57.8 6e-09 35.7 0.1 10.5 4 2 8 12 12 12 12 FNIP Repeat DUF3384 PF11864.3 EGC30959.1 - 0.014 13.9 20.3 0.0077 14.7 10.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3384) Orthopox_F7 PF05813.7 EGC30961.1 - 0.081 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Orthopoxvirus F7 protein SAM_1 PF00536.25 EGC30962.1 - 0.0011 19.1 0.0 0.0013 18.8 0.0 1.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC30962.1 - 0.061 13.1 0.0 0.071 12.9 0.0 1.1 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) FNIP PF05725.7 EGC30963.1 - 1.3e-39 133.8 57.5 1.1e-10 41.3 1.1 5.4 1 1 6 7 7 7 7 FNIP Repeat DUF4451 PF14616.1 EGC30965.1 - 0.0023 17.6 0.6 0.0029 17.3 0.4 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4451) DDE_Tnp_1_7 PF13843.1 EGC30966.1 - 8.1e-24 84.3 0.5 2.1e-23 82.9 0.3 1.6 1 1 0 1 1 1 1 Transposase IS4 Nop14 PF04147.7 EGC30966.1 - 0.027 12.4 14.1 0.038 11.9 9.8 1.1 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGC30966.1 - 0.64 7.9 8.8 0.93 7.4 6.1 1.2 1 0 0 1 1 1 0 CDC45-like protein CobT PF06213.7 EGC30966.1 - 0.72 8.9 12.9 1.1 8.3 9.0 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NOA36 PF06524.7 EGC30966.1 - 0.8 8.9 13.5 1.6 7.9 9.4 1.4 1 0 0 1 1 1 0 NOA36 protein Sporozoite_P67 PF05642.6 EGC30966.1 - 2.2 6.0 5.6 3.4 5.4 3.9 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen SDA1 PF05285.7 EGC30966.1 - 3.3 6.9 17.4 5.3 6.2 12.1 1.2 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EGC30966.1 - 5.3 5.3 17.1 7.9 4.8 11.9 1.2 1 0 0 1 1 1 0 Daxx Family Pex14_N PF04695.8 EGC30967.1 - 0.13 12.3 6.0 0.29 11.1 4.2 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Pkinase PF00069.20 EGC30968.1 - 1.5e-37 129.1 0.0 2.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30968.1 - 3e-20 72.4 0.0 3.8e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC30968.1 - 0.0026 17.5 0.0 0.14 11.8 0.0 2.4 2 1 0 2 2 2 1 Phosphotransferase enzyme family GHMP_kinases_N PF00288.21 EGC30968.1 - 0.084 12.9 0.9 0.21 11.6 0.6 1.7 1 0 0 1 1 1 0 GHMP kinases N terminal domain DUF3861 PF12977.2 EGC30968.1 - 0.12 12.5 0.1 0.29 11.2 0.1 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) Ras PF00071.17 EGC30969.1 - 1.7e-61 206.3 0.2 2e-61 206.1 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30969.1 - 3e-19 69.6 0.0 4.8e-19 68.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30969.1 - 3.9e-12 45.7 0.1 4.9e-12 45.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC30969.1 - 3.2e-05 23.8 0.0 4.6e-05 23.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGC30969.1 - 0.00024 20.3 0.0 0.00028 20.1 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC30969.1 - 0.0014 18.1 0.1 0.0057 16.1 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EGC30969.1 - 0.0097 15.8 0.1 0.021 14.7 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC30969.1 - 0.05 13.7 0.0 0.12 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGC30969.1 - 0.064 12.4 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Ras PF00071.17 EGC30970.1 - 7e-38 129.5 0.4 8.2e-38 129.3 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC30970.1 - 3.5e-15 56.5 0.1 5.4e-15 55.9 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC30970.1 - 3.7e-08 32.7 0.1 5.5e-08 32.2 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC30970.1 - 4.6e-06 26.5 0.0 6.6e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC30970.1 - 5.1e-06 26.0 0.1 0.00011 21.7 0.0 2.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGC30970.1 - 0.0037 17.2 0.0 0.0076 16.2 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EGC30970.1 - 0.0049 16.4 0.0 0.044 13.3 0.0 2.0 1 1 0 2 2 2 1 AAA domain FeoB_N PF02421.13 EGC30970.1 - 0.0061 15.8 0.0 0.26 10.5 0.0 2.5 1 1 0 1 1 1 1 Ferrous iron transport protein B MCM PF00493.18 EGC30970.1 - 0.012 14.4 0.2 0.086 11.6 0.0 1.9 2 0 0 2 2 2 0 MCM2/3/5 family Gtr1_RagA PF04670.7 EGC30970.1 - 0.022 13.8 0.2 0.028 13.5 0.1 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC30970.1 - 0.024 13.8 0.4 0.11 11.7 0.0 1.9 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit ABC_tran PF00005.22 EGC30970.1 - 0.04 14.2 0.0 0.072 13.3 0.0 1.4 1 1 0 1 1 1 0 ABC transporter DUF1911 PF08929.5 EGC30970.1 - 0.096 13.3 0.2 0.19 12.4 0.1 1.5 2 0 0 2 2 1 0 Domain of unknown function (DUF1911) Mg_chelatase PF01078.16 EGC30970.1 - 0.13 11.4 0.0 0.21 10.7 0.0 1.2 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI ALMT PF11744.3 EGC30971.1 - 2.6e-45 154.8 11.4 2.6e-45 154.8 7.9 3.6 2 2 0 2 2 2 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EGC30971.1 - 2.5e-16 59.7 15.6 2.5e-16 59.7 10.8 2.6 2 0 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGC30971.1 - 9.3e-10 37.5 7.0 2.1e-09 36.4 4.8 1.5 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF4404 PF14357.1 EGC30972.1 - 0.006 16.9 0.6 0.022 15.1 0.2 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4404) CCDC-167 PF15188.1 EGC30972.1 - 0.44 10.5 7.9 0.94 9.4 5.5 1.6 1 1 0 1 1 1 0 Coiled-coil domain-containing protein 167 DUF2098 PF09871.4 EGC30972.1 - 1.3 8.9 4.4 1.9 8.5 3.1 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) GrpE PF01025.14 EGC30972.1 - 7.9 6.0 8.9 42 3.6 4.3 2.1 2 0 0 2 2 2 0 GrpE Complex1_LYR PF05347.10 EGC30973.1 - 0.049 13.4 3.4 0.073 12.8 2.4 1.5 1 1 0 1 1 1 0 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC30973.1 - 0.096 12.9 3.2 0.12 12.5 2.2 1.3 1 1 0 1 1 1 0 Complex1_LYR-like DcpS_C PF11969.3 EGC30974.1 - 1.3e-25 89.8 0.7 1.7e-25 89.4 0.5 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGC30974.1 - 2.3e-11 44.0 0.5 3.8e-11 43.3 0.4 1.3 1 0 0 1 1 1 1 HIT domain DUF2410 PF10307.4 EGC30975.1 - 5.8e-48 162.9 0.9 9.3e-48 162.2 0.6 1.3 1 0 0 1 1 1 1 Hypothetical protein (DUF2410) Pyrophosphatase PF00719.14 EGC30976.1 - 2.6e-42 143.9 0.7 2.9e-42 143.7 0.5 1.0 1 0 0 1 1 1 1 Inorganic pyrophosphatase P4Ha_N PF08336.6 EGC30976.1 - 0.03 14.1 0.2 0.068 12.9 0.0 1.6 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region TUDOR PF00567.19 EGC30977.1 - 0.076 12.8 0.1 0.57 10.0 0.1 2.4 2 0 0 2 2 2 0 Tudor domain PG_binding_1 PF01471.13 EGC30978.1 - 4.1e-07 29.8 0.0 8.8e-07 28.8 0.0 1.6 1 0 0 1 1 1 1 Putative peptidoglycan binding domain YkuD PF03734.9 EGC30978.1 - 0.00016 21.9 0.0 0.00024 21.3 0.0 1.3 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain CCAP PF11105.3 EGC30979.1 - 0.002 17.8 0.2 0.0026 17.4 0.2 1.2 1 0 0 1 1 1 1 Arthropod cardioacceleratory peptide 2a SNF2_N PF00176.18 EGC30980.1 - 3.7e-58 196.7 0.0 6.5e-58 195.8 0.0 1.4 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC30980.1 - 6.5e-11 41.9 0.0 1.6e-10 40.7 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain WD40 PF00400.27 EGC30981.1 - 1.6e-18 65.8 0.2 2.6e-07 30.2 0.0 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat Ricin_B_lectin PF00652.17 EGC30981.1 - 0.0084 16.1 1.1 0.078 13.0 0.0 2.5 2 0 0 2 2 2 1 Ricin-type beta-trefoil lectin domain DUF1513 PF07433.6 EGC30981.1 - 0.053 12.4 0.0 5.4 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1513) HAND PF09110.6 EGC30981.1 - 0.17 12.2 5.0 0.39 11.1 3.4 1.6 1 0 0 1 1 1 0 HAND F-box-like PF12937.2 EGC30983.1 - 0.028 14.1 0.1 0.14 11.9 0.0 2.2 2 0 0 2 2 2 0 F-box-like DDE_Tnp_4 PF13359.1 EGC30984.1 - 3.1e-10 39.8 0.0 5.4e-10 39.0 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EGC30984.1 - 1.5e-05 24.4 0.3 2.8e-05 23.5 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease Med3 PF11593.3 EGC30984.1 - 0.13 11.4 9.6 0.22 10.7 6.7 1.3 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Kelch_6 PF13964.1 EGC30985.1 - 1.7e-08 34.2 11.9 0.12 12.5 0.0 5.6 5 1 0 5 5 5 4 Kelch motif Kelch_3 PF13415.1 EGC30985.1 - 1.1e-06 28.6 1.9 1.4 9.1 0.0 4.7 5 0 0 5 5 5 3 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC30985.1 - 0.016 14.7 10.4 5.4 6.6 0.1 5.4 5 0 0 5 5 5 0 Kelch motif Kelch_4 PF13418.1 EGC30985.1 - 0.018 14.8 2.0 3 7.6 0.0 4.4 5 0 0 5 5 5 0 Galactose oxidase, central domain Hemopexin PF00045.14 EGC30985.1 - 0.029 14.1 0.4 0.51 10.1 0.0 2.8 3 0 0 3 3 3 0 Hemopexin Kelch_5 PF13854.1 EGC30985.1 - 7.1 6.6 11.9 1.3 9.0 0.1 4.2 5 0 0 5 5 5 0 Kelch motif Pkinase PF00069.20 EGC30986.1 - 2e-45 154.9 1.4 4e-30 104.8 0.1 2.7 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30986.1 - 8.1e-29 100.4 0.0 8.8e-21 74.1 0.0 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase Ribosomal_60s PF00428.14 EGC30987.1 - 0.0091 16.3 0.0 0.014 15.7 0.0 1.4 1 0 0 1 1 1 1 60s Acidic ribosomal protein A2M_N PF01835.14 EGC30989.1 - 0.056 13.7 0.0 0.11 12.8 0.0 1.4 1 0 0 1 1 1 0 MG2 domain 2-Hacid_dh_C PF02826.14 EGC30990.1 - 1.4e-46 157.8 0.0 3.2e-46 156.6 0.0 1.6 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC30990.1 - 1.1e-34 118.8 0.0 1.4e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC30990.1 - 0.00016 21.5 0.0 0.00049 19.9 0.0 1.9 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ACT PF01842.20 EGC30990.1 - 0.00076 18.9 0.4 0.0057 16.1 0.0 2.3 2 0 0 2 2 2 1 ACT domain PAP2 PF01569.16 EGC30991.1 - 1.1e-10 41.3 4.6 1.1e-10 41.3 3.2 2.2 2 1 0 2 2 2 1 PAP2 superfamily Cor1 PF04803.7 EGC30992.1 - 0.0094 15.7 1.6 1.9 8.2 1.6 2.3 2 0 0 2 2 2 2 Cor1/Xlr/Xmr conserved region FNIP PF05725.7 EGC30992.1 - 0.013 15.4 17.4 0.29 11.1 0.5 4.4 3 1 0 4 4 4 0 FNIP Repeat Pkinase PF00069.20 EGC30993.1 - 1.7e-42 145.3 0.2 2.2e-42 144.9 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC30993.1 - 1.8e-08 33.8 0.0 5.4e-08 32.2 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC30993.1 - 0.0012 17.9 0.1 0.0036 16.4 0.0 1.8 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGC30993.1 - 0.0058 15.4 0.2 0.0095 14.7 0.1 1.3 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase APH PF01636.18 EGC30993.1 - 0.044 13.4 0.0 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC30993.1 - 0.059 12.9 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGC30993.1 - 0.098 11.9 0.2 1.4 8.2 0.0 2.3 2 0 0 2 2 2 0 RIO1 family RNA_pol_A_bac PF01000.21 EGC30994.1 - 8.1e-28 96.8 0.1 3.9e-27 94.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGC30994.1 - 3e-20 71.0 0.0 4.5e-20 70.5 0.0 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain Ion_trans PF00520.26 EGC30995.1 - 4.3e-08 32.6 7.5 4.3e-08 32.6 5.2 2.2 2 1 0 2 2 2 1 Ion transport protein DUF2762 PF10960.3 EGC30995.1 - 0.019 14.6 0.8 1.2 8.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) PhaG_MnhG_YufB PF03334.9 EGC30995.1 - 0.18 11.8 3.0 9 6.4 0.0 2.4 2 0 0 2 2 2 0 Na+/H+ antiporter subunit MARVEL PF01284.18 EGC30995.1 - 1.1 9.0 12.9 2.2 8.0 0.1 2.6 3 0 0 3 3 3 0 Membrane-associating domain NfeD PF01957.13 EGC30995.1 - 1.3 9.1 4.4 9.4 6.3 0.7 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4233 PF14017.1 EGC30995.1 - 3.6 7.5 9.3 0.51 10.2 0.4 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4233) BK_channel_a PF03493.13 EGC30996.1 - 4.7e-21 74.6 0.6 1.2e-20 73.3 0.1 2.0 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EGC30996.1 - 1.2e-10 40.9 3.1 2.9e-10 39.7 2.1 1.6 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.13 EGC30996.1 - 0.00028 20.8 0.0 0.4 10.6 0.0 2.6 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.26 EGC30996.1 - 0.037 13.2 4.4 0.064 12.5 3.1 1.4 1 0 0 1 1 1 0 Ion transport protein DUF1049 PF06305.6 EGC30997.1 - 0.077 12.4 0.1 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) DUF3951 PF13131.1 EGC30997.1 - 0.17 11.7 0.6 0.28 11.0 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3951) FoP_duplication PF13865.1 EGC30998.1 - 0.25 11.7 37.5 2e+03 -0.7 25.9 3.2 1 1 0 1 1 1 0 C-terminal duplication domain of Friend of PRMT1 Ribosomal_L34 PF00468.12 EGC30999.1 - 6.8e-18 64.0 9.1 1.2e-17 63.2 6.3 1.4 1 0 0 1 1 1 1 Ribosomal protein L34 Zip PF02535.17 EGC31000.1 - 6.9e-38 130.4 14.7 1.2e-37 129.6 10.2 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2689 PF10894.3 EGC31000.1 - 0.081 12.7 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) HupE_UreJ PF04955.7 EGC31000.1 - 0.53 9.5 14.7 0.14 11.4 4.9 3.0 2 2 1 3 3 3 0 HupE / UreJ protein zf-CSL PF05207.8 EGC31001.1 - 7.6e-22 76.5 4.9 1.3e-21 75.8 3.4 1.4 1 0 0 1 1 1 1 CSL zinc finger DnaJ PF00226.26 EGC31001.1 - 8.2e-20 70.3 1.7 1.3e-19 69.6 1.2 1.3 1 0 0 1 1 1 1 DnaJ domain DUF2250 PF10007.4 EGC31001.1 - 0.051 13.4 0.3 0.078 12.8 0.2 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2250) zinc_ribbon_5 PF13719.1 EGC31001.1 - 0.85 9.2 3.6 0.58 9.7 1.2 1.7 2 0 0 2 2 2 0 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGC31001.1 - 1.2 8.8 3.8 0.9 9.2 1.4 1.8 2 0 0 2 2 2 0 zinc-ribbon domain Cpn60_TCP1 PF00118.19 EGC31002.1 - 1.7e-145 485.3 5.0 1.9e-145 485.1 3.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family ECH PF00378.15 EGC31003.1 - 8.4e-24 84.0 0.0 9.9e-24 83.7 0.0 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Laminin_II PF06009.7 EGC31004.1 - 0.01 15.5 2.5 0.033 13.9 0.4 2.7 2 1 0 2 2 2 0 Laminin Domain II Pup PF05639.6 EGC31004.1 - 1.2 9.6 6.7 34 5.0 4.7 2.6 1 1 0 1 1 1 0 Pup-like protein Pkinase PF00069.20 EGC31005.1 - 2.4e-77 259.6 0.0 4.2e-77 258.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31005.1 - 3.1e-41 141.1 0.0 4.6e-41 140.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGC31005.1 - 3e-15 56.0 0.3 6.9e-15 54.9 0.2 1.7 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGC31005.1 - 6.5e-11 41.7 0.0 1.2e-10 40.8 0.0 1.5 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC31005.1 - 6.4e-05 22.1 0.0 0.00011 21.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family DEAD PF00270.24 EGC31006.1 - 1.4e-46 158.0 0.0 3.8e-46 156.6 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC31006.1 - 9.9e-25 86.2 0.0 3.8e-24 84.3 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Toxin_40 PF15520.1 EGC31006.1 - 0.091 12.2 0.0 0.15 11.4 0.0 1.2 1 0 0 1 1 1 0 Putative toxin 40 AAA_22 PF13401.1 EGC31006.1 - 0.16 12.1 1.7 1.3 9.1 0.2 2.8 2 1 0 2 2 2 0 AAA domain TRAPP PF04051.11 EGC31008.1 - 9.8e-46 155.0 0.0 1.1e-45 154.8 0.0 1.0 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Zip PF02535.17 EGC31009.1 - 1.1e-43 149.4 12.2 1.3e-43 149.2 8.5 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter DUF2689 PF10894.3 EGC31009.1 - 0.13 12.0 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2689) TMEMspv1-c74-12 PF11044.3 EGC31009.1 - 0.24 10.9 4.0 5.5 6.6 0.2 2.9 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein DUF1275 PF06912.6 EGC31009.1 - 2.4 7.2 9.3 0.23 10.6 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1275) RCC1 PF00415.13 EGC31010.1 - 8.9e-38 128.2 7.0 3.8e-10 39.8 0.0 6.4 5 2 0 5 5 5 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC31010.1 - 3.3e-25 87.0 26.7 8.8e-08 31.5 0.1 6.7 6 1 0 6 6 6 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGC31010.1 - 1.2e-15 57.4 3.7 1.1e-07 31.8 0.4 2.7 2 1 0 2 2 2 2 BTB/POZ domain Ank_4 PF13637.1 EGC31010.1 - 8e-12 45.3 0.1 1.7e-07 31.5 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC31010.1 - 1.3e-08 34.7 0.0 4.7e-08 33.0 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank PF00023.25 EGC31010.1 - 1.6e-06 27.6 0.2 3.3e-05 23.4 0.0 3.1 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EGC31010.1 - 1.9e-06 28.0 0.0 5.2e-06 26.7 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC31010.1 - 2.1e-05 24.3 0.0 0.00031 20.6 0.0 3.0 2 0 0 2 2 2 1 Ankyrin repeat DUF2207 PF09972.4 EGC31011.1 - 0.4 9.2 11.8 0.029 12.9 3.9 2.0 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) SUR7 PF06687.7 EGC31011.1 - 4.6 6.7 14.1 0.23 10.9 5.0 2.2 2 1 0 2 2 2 0 SUR7/PalI family SAM_decarbox PF01536.11 EGC31012.1 - 4.9e-103 344.2 0.2 6e-103 343.9 0.1 1.0 1 0 0 1 1 1 1 Adenosylmethionine decarboxylase DUF3986 PF13143.1 EGC31012.1 - 0.12 12.8 1.1 4.5 7.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3986) Peptidase_S28 PF05577.7 EGC31013.1 - 2.7e-81 273.3 7.3 3.6e-81 272.9 5.0 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EGC31013.1 - 3e-06 27.3 0.0 1e-05 25.5 0.0 1.8 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC31013.1 - 0.013 14.7 0.0 0.03 13.5 0.0 1.6 1 0 0 1 1 1 0 Prolyl oligopeptidase family Arv1 PF04161.8 EGC31014.1 - 4.8e-55 186.7 4.6 6e-55 186.3 3.2 1.1 1 0 0 1 1 1 1 Arv1-like family RNA_pol_N PF01194.12 EGC31014.1 - 0.16 12.0 2.3 4.3 7.4 0.0 2.3 1 1 1 2 2 2 0 RNA polymerases N / 8 kDa subunit Mpv17_PMP22 PF04117.7 EGC31015.1 - 3.6e-23 80.9 0.9 3.6e-23 80.9 0.6 2.3 1 1 1 2 2 2 1 Mpv17 / PMP22 family UPF0546 PF10639.4 EGC31015.1 - 0.027 14.2 0.2 0.027 14.2 0.2 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 DUF1113 PF06541.6 EGC31015.1 - 0.3 10.8 4.8 0.11 12.2 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1113) TauE PF01925.14 EGC31015.1 - 0.41 10.0 4.6 1.6 8.0 3.3 1.8 1 1 0 1 1 1 0 Sulfite exporter TauE/SafE QueT PF06177.6 EGC31015.1 - 0.75 9.7 5.3 0.33 10.9 0.8 2.0 1 1 1 2 2 2 0 QueT transporter Caveolin PF01146.12 EGC31015.1 - 1.1 8.8 6.6 1.9 8.0 0.7 2.6 1 1 1 2 2 2 0 Caveolin HSP70 PF00012.15 EGC31016.1 - 8e-139 463.3 5.6 8e-139 463.3 3.9 2.1 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGC31016.1 - 2.6e-10 39.4 0.1 8.8e-10 37.6 0.0 1.8 2 0 0 2 2 2 1 MreB/Mbl protein FGGY_C PF02782.11 EGC31016.1 - 0.0019 17.8 0.0 0.0068 16.0 0.0 1.9 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain SapB_1 PF05184.10 EGC31016.1 - 0.081 12.7 0.8 2.6 7.9 0.0 3.0 2 0 0 2 2 2 0 Saposin-like type B, region 1 CTP_transf_2 PF01467.21 EGC31017.1 - 1.9e-22 79.9 0.1 3.9e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 Cytidylyltransferase DASH_Duo1 PF08651.5 EGC31018.1 - 0.055 13.0 0.6 0.47 10.0 0.1 2.4 2 1 0 2 2 2 0 DASH complex subunit Duo1 adh_short PF00106.20 EGC31019.1 - 6.1e-20 71.7 0.0 7.9e-20 71.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC31019.1 - 1.7e-09 37.7 0.0 2.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC31019.1 - 0.00026 20.6 0.0 0.00043 19.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC31019.1 - 0.048 12.7 0.0 0.071 12.2 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC31019.1 - 0.086 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding CAF-1_p150 PF11600.3 EGC31020.1 - 0.00044 19.7 45.2 0.00044 19.7 31.3 2.5 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal BSMAP PF12280.3 EGC31020.1 - 1.5 8.6 16.6 0.43 10.4 9.0 1.9 1 1 0 1 1 1 0 Brain specific membrane anchored protein Mucin PF01456.12 EGC31020.1 - 7.7 6.2 23.9 16 5.2 16.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein MutS_V PF00488.16 EGC31021.1 - 2e-95 318.6 0.0 4e-95 317.6 0.0 1.5 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC31021.1 - 2.5e-36 125.3 4.0 3e-36 125.1 1.7 1.9 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EGC31021.1 - 4.3e-13 49.2 5.2 4.3e-13 49.2 3.6 2.5 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EGC31021.1 - 9.9e-13 48.3 0.1 9.9e-13 48.3 0.0 2.7 3 0 0 3 3 3 1 MutS domain II MutS_I PF01624.15 EGC31021.1 - 1.4e-05 25.0 0.2 0.0013 18.7 0.1 2.6 2 0 0 2 2 2 1 MutS domain I Peptidase_M16 PF00675.15 EGC31021.1 - 0.0047 16.6 1.5 0.37 10.5 0.0 2.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) PB1 PF00564.19 EGC31021.1 - 0.033 13.8 1.7 0.13 11.9 0.6 2.3 1 1 1 2 2 2 0 PB1 domain Glyco_hydro_35 PF01301.14 EGC31022.1 - 9.1e-99 330.7 0.4 9.1e-99 330.7 0.3 2.4 3 0 0 3 3 3 1 Glycosyl hydrolases family 35 NPL4 PF05021.10 EGC31023.1 - 5.3e-51 173.6 0.0 7.7e-51 173.0 0.0 1.2 1 0 0 1 1 1 1 NPL4 family JAB PF01398.16 EGC31023.1 - 2e-05 24.2 0.0 4.7e-05 23.0 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease UN_NPL4 PF11543.3 EGC31023.1 - 0.00074 19.7 0.0 0.0031 17.7 0.0 2.1 1 1 0 1 1 1 1 Nuclear pore localisation protein NPL4 YukD PF08817.5 EGC31023.1 - 0.081 13.4 0.0 0.16 12.5 0.0 1.4 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD Peptidase_M20 PF01546.23 EGC31024.1 - 4.9e-20 71.8 0.2 7.2e-20 71.2 0.1 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 DDE_Tnp_4 PF13359.1 EGC31024.1 - 7.6e-13 48.3 0.0 1.4e-12 47.4 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease M20_dimer PF07687.9 EGC31024.1 - 1.4e-08 34.4 0.1 4.9e-08 32.7 0.1 1.8 2 0 0 2 2 2 1 Peptidase dimerisation domain DDE_Tnp_1_3 PF13612.1 EGC31024.1 - 0.00076 19.2 0.0 0.0015 18.3 0.0 1.4 1 0 0 1 1 1 1 Transposase DDE domain NADH_Oxid_Nqo15 PF11497.3 EGC31024.1 - 0.052 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 NADH-quinone oxidoreductase chain 15 Kelch_4 PF13418.1 EGC31025.1 - 2.1e-48 161.8 10.2 2.2e-09 36.9 0.2 6.4 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC31025.1 - 3.3e-38 128.9 5.8 9.2e-08 32.0 0.1 7.3 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC31025.1 - 4.7e-28 96.6 4.6 0.0001 22.1 0.1 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EGC31025.1 - 1.1e-23 82.3 8.8 8.1e-07 28.9 0.1 5.7 5 0 0 5 5 5 5 Kelch motif Kelch_1 PF01344.20 EGC31025.1 - 1.2e-17 63.1 6.5 4.9e-05 22.7 0.2 5.9 6 0 0 6 6 6 3 Kelch motif Kelch_2 PF07646.10 EGC31025.1 - 2.4e-17 61.9 7.7 0.00069 19.2 0.1 6.2 6 0 0 6 6 6 5 Kelch motif zf-C3HC4_3 PF13920.1 EGC31025.1 - 1.7e-11 43.6 12.6 1.7e-11 43.6 8.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) K-box PF01486.12 EGC31025.1 - 1.5e-07 31.1 5.7 1.5e-07 31.1 3.9 4.0 2 2 2 4 4 4 1 K-box region zf-C3HC4_2 PF13923.1 EGC31025.1 - 0.0039 17.1 15.6 0.011 15.7 10.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF357 PF04010.8 EGC31025.1 - 0.072 12.7 0.5 0.48 10.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF357) EGF_2 PF07974.8 EGC31027.1 - 7e-07 29.2 31.9 0.00024 21.1 8.2 3.1 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC31027.1 - 0.013 15.5 16.3 0.031 14.3 1.2 3.1 3 0 0 3 3 3 0 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC31027.1 - 0.099 12.5 22.5 1.2 9.1 5.8 2.9 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) PfkB PF00294.19 EGC31028.1 - 1.6e-11 43.9 0.0 2e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase ELO PF01151.13 EGC31030.1 - 1.1e-61 208.3 24.5 1.3e-61 208.1 17.0 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family DUF3290 PF11694.3 EGC31030.1 - 0.04 13.6 0.7 0.04 13.6 0.5 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) Polysacc_synt_C PF14667.1 EGC31030.1 - 0.56 9.9 11.7 0.42 10.4 0.2 2.5 2 1 0 2 2 2 0 Polysaccharide biosynthesis C-terminal domain Myotub-related PF06602.9 EGC31031.1 - 4.5e-121 403.9 2.1 4.5e-121 403.9 1.4 2.5 3 0 0 3 3 3 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGC31031.1 - 0.023 14.9 0.0 0.023 14.9 0.0 3.8 3 1 0 3 3 3 0 Tyrosine phosphatase family zf-C3HC4_3 PF13920.1 EGC31031.1 - 9.2 6.0 8.5 3.3 7.4 3.1 2.2 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF928 PF06051.7 EGC31032.1 - 0.024 14.2 4.7 0.042 13.4 3.2 1.4 1 0 0 1 1 1 0 Domain of Unknown Function (DUF928) zf-RING_2 PF13639.1 EGC31033.1 - 5.6e-11 42.0 9.6 9.1e-11 41.4 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31033.1 - 1.4e-08 34.2 7.2 2.2e-08 33.6 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31033.1 - 5.2e-07 29.2 11.0 1e-06 28.3 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31033.1 - 1.3e-06 28.4 7.7 3.1e-06 27.2 5.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC31033.1 - 1.4e-06 28.2 10.0 2.3e-06 27.5 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31033.1 - 1.2e-05 24.9 9.0 2e-05 24.2 6.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC31033.1 - 0.0039 16.7 10.5 0.0068 15.9 7.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain IBR PF01485.16 EGC31033.1 - 0.019 14.8 10.3 0.047 13.5 7.1 1.6 1 0 0 1 1 1 0 IBR domain zf-C3HC4_4 PF15227.1 EGC31033.1 - 0.026 14.3 10.0 0.048 13.5 6.0 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC31033.1 - 0.038 13.5 5.0 0.092 12.3 3.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EGC31033.1 - 0.068 12.8 3.6 0.27 10.9 2.5 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC31033.1 - 0.095 12.5 4.5 0.21 11.4 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC31033.1 - 0.1 12.4 7.0 0.2 11.5 4.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MIZ PF02891.15 EGC31033.1 - 0.48 9.9 7.9 1 8.9 5.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FNIP PF05725.7 EGC31034.1 - 2.6e-174 565.0 76.5 1e-15 57.3 0.1 13.3 5 2 8 16 16 16 16 FNIP Repeat Phage_min_tail PF05939.8 EGC31034.1 - 1.4e-06 28.1 0.1 55 3.7 0.0 8.8 4 2 6 11 11 11 0 Phage minor tail protein DUF4495 PF14906.1 EGC31034.1 - 0.19 10.6 0.0 1.6e+02 1.0 0.0 4.8 4 2 3 7 7 7 0 Domain of unknown function (DUF4495) Thg1 PF04446.7 EGC31035.1 - 7.1e-40 135.7 0.1 2.4e-39 134.0 0.0 1.8 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EGC31035.1 - 8.2e-13 48.1 0.2 1.5e-12 47.2 0.1 1.4 1 0 0 1 1 1 1 Thg1 C terminal domain Med12-LCEWAV PF12145.3 EGC31036.1 - 0.23 9.9 7.6 0.31 9.4 5.2 1.2 1 0 0 1 1 1 0 Eukaryotic Mediator 12 subunit domain DUF262 PF03235.9 EGC31036.1 - 2.7 7.9 11.2 3.3 7.6 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function DUF262 PA26 PF04636.8 EGC31036.1 - 2.7 6.5 8.6 3.1 6.3 6.0 1.0 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) eIF-3c_N PF05470.7 EGC31036.1 - 3.9 5.4 22.6 4.7 5.1 15.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 EGC31036.1 - 5.3 6.1 44.8 7.2 5.7 31.0 1.2 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Paramyxo_ncap PF00973.14 EGC31036.1 - 5.6 5.5 12.2 6.3 5.3 8.4 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein LRR_6 PF13516.1 EGC31037.1 - 1.5e-12 46.2 84.6 0.023 14.7 0.1 17.0 17 0 0 17 17 17 11 Leucine Rich repeat LRR_1 PF00560.28 EGC31037.1 - 6.9e-06 25.3 46.8 3.5 8.0 0.0 15.0 14 2 0 14 14 14 4 Leucine Rich Repeat LRR_4 PF12799.2 EGC31037.1 - 0.0076 15.8 0.8 0.0076 15.8 0.5 11.4 6 4 1 11 11 11 6 Leucine Rich repeats (2 copies) DUF1510 PF07423.6 EGC31038.1 - 0.00026 20.4 5.7 0.00047 19.5 3.9 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 EGC31038.1 - 0.0032 17.4 1.4 0.01 15.7 0.9 1.9 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region CopD PF05425.8 EGC31038.1 - 0.008 16.3 0.5 0.008 16.3 0.4 3.0 4 1 0 4 4 3 1 Copper resistance protein D RCR PF12273.3 EGC31038.1 - 0.011 16.3 4.3 0.011 16.3 3.0 3.4 3 0 0 3 3 3 0 Chitin synthesis regulation, resistance to Congo red DUF4220 PF13968.1 EGC31038.1 - 0.017 14.2 0.2 0.017 14.2 0.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4220) PGG PF13962.1 EGC31038.1 - 0.018 14.6 11.7 1.2 8.7 0.4 3.9 3 0 0 3 3 3 0 Domain of unknown function Menin PF05053.8 EGC31038.1 - 0.069 11.3 5.7 0.097 10.8 3.9 1.2 1 0 0 1 1 1 0 Menin DUF3382 PF11862.3 EGC31038.1 - 0.45 10.4 6.6 4.8 7.1 0.8 3.5 3 1 1 4 4 4 0 Domain of unknown function (DUF3382) Shisa PF13908.1 EGC31038.1 - 0.55 10.3 11.7 1.4 9.0 0.7 3.8 3 1 1 4 4 4 0 Wnt and FGF inhibitory regulator IncA PF04156.9 EGC31038.1 - 6.2 6.3 0.0 6.2 6.3 0.0 2.7 3 0 0 3 3 2 0 IncA protein Pox_Ag35 PF03286.9 EGC31038.1 - 9.5 5.6 14.5 15 5.0 10.1 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF2956 PF11169.3 EGC31038.1 - 9.5 6.2 8.9 12 5.8 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) W2 PF02020.13 EGC31039.1 - 2.7e-21 75.2 9.1 2.7e-21 75.2 6.3 2.7 3 0 0 3 3 3 1 eIF4-gamma/eIF5/eIF2-epsilon Hexapep PF00132.19 EGC31039.1 - 6e-11 41.3 16.1 5.1e-05 22.5 2.2 4.2 2 1 2 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transferase PF00483.18 EGC31039.1 - 8.9e-10 38.2 0.0 2.2e-09 36.9 0.0 1.7 2 0 0 2 2 2 1 Nucleotidyl transferase Hexapep_2 PF14602.1 EGC31039.1 - 9.8e-06 25.0 5.9 0.00024 20.6 0.1 3.6 3 1 1 4 4 4 1 Hexapeptide repeat of succinyl-transferase DUF2543 PF10820.3 EGC31039.1 - 0.0072 16.3 0.1 0.021 14.8 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2543) NTP_transf_3 PF12804.2 EGC31039.1 - 0.018 15.1 0.0 0.031 14.3 0.0 1.3 1 0 0 1 1 1 0 MobA-like NTP transferase domain TPP_enzyme_N PF02776.13 EGC31039.1 - 0.16 11.4 0.0 4.4 6.7 0.0 2.2 1 1 0 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain PK PF00224.16 EGC31041.1 - 1.5e-151 503.9 9.5 2.1e-151 503.4 6.6 1.1 1 0 0 1 1 1 1 Pyruvate kinase, barrel domain PK_C PF02887.11 EGC31041.1 - 1.3e-28 98.8 1.7 3.2e-28 97.6 1.1 1.7 1 0 0 1 1 1 1 Pyruvate kinase, alpha/beta domain HpcH_HpaI PF03328.9 EGC31041.1 - 4.4e-05 22.4 2.7 0.0001 21.3 1.9 1.7 1 1 0 1 1 1 1 HpcH/HpaI aldolase/citrate lyase family BRCA-2_OB1 PF09103.5 EGC31041.1 - 0.012 15.2 0.3 0.17 11.5 0.0 2.4 2 0 0 2 2 2 0 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 TPP_enzyme_N PF02776.13 EGC31041.1 - 0.057 12.9 0.0 0.38 10.2 0.0 2.0 1 1 1 2 2 2 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain EGF_2 PF07974.8 EGC31042.1 - 0.0091 16.1 9.6 0.025 14.7 6.6 1.8 1 0 0 1 1 1 1 EGF-like domain EphA2_TM PF14575.1 EGC31043.1 - 0.017 15.4 1.0 0.059 13.7 0.5 2.0 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain YajC PF02699.10 EGC31043.1 - 0.02 14.5 0.3 0.045 13.4 0.2 1.5 1 0 0 1 1 1 0 Preprotein translocase subunit Adeno_E3_CR2 PF02439.10 EGC31043.1 - 0.039 13.5 2.3 0.077 12.5 1.6 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DUF1191 PF06697.7 EGC31043.1 - 0.048 12.4 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Arif-1 PF06770.6 EGC31043.1 - 0.054 12.8 0.1 0.08 12.3 0.1 1.2 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF2668 PF10873.3 EGC31043.1 - 0.082 13.0 0.9 0.14 12.3 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2668) DUF2910 PF11139.3 EGC31043.1 - 0.11 11.6 0.0 0.15 11.1 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2910) Syndecan PF01034.15 EGC31043.1 - 0.13 11.9 0.3 0.25 10.9 0.2 1.5 1 0 0 1 1 1 0 Syndecan domain PsaL PF02605.10 EGC31043.1 - 0.14 11.6 0.1 0.25 10.8 0.1 1.4 1 0 0 1 1 1 0 Photosystem I reaction centre subunit XI Vpu PF00558.14 EGC31043.1 - 0.24 10.9 1.2 0.38 10.3 0.8 1.3 1 0 0 1 1 1 0 Vpu protein Fz PF01392.17 EGC31044.1 - 0.16 12.3 4.0 0.32 11.3 2.8 1.5 1 0 0 1 1 1 0 Fz domain Glyco_hydro_38 PF01074.17 EGC31045.1 - 2e-53 181.4 2.6 2.4e-43 148.4 0.8 2.8 2 1 1 3 3 3 2 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC31045.1 - 2.3e-19 69.3 0.1 1.3e-18 66.9 0.1 2.4 1 0 0 1 1 1 1 Alpha mannosidase, middle domain TMEM154 PF15102.1 EGC31045.1 - 0.0012 18.5 0.1 0.0025 17.5 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family OSTbeta PF15048.1 EGC31045.1 - 0.025 14.6 2.3 0.067 13.2 1.6 1.7 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein Prenyltrans_1 PF13243.1 EGC31045.1 - 0.026 14.5 0.0 0.093 12.7 0.0 1.9 1 1 0 1 1 1 0 Prenyltransferase-like Chordopox_A13L PF05961.6 EGC31045.1 - 0.068 13.1 6.3 0.036 13.9 1.4 3.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein SKG6 PF08693.5 EGC31045.1 - 0.2 11.0 2.0 0.46 9.8 1.4 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain tRNA-synt_2b PF00587.20 EGC31046.1 - 2.7e-63 212.6 0.1 6.8e-63 211.3 0.1 1.7 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC31046.1 - 4.8e-23 80.9 2.2 2.8e-22 78.4 0.0 3.1 3 1 0 3 3 3 1 Anticodon binding domain DUF77 PF01910.12 EGC31046.1 - 0.029 14.0 0.0 0.086 12.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function DUF77 DUF4479 PF14794.1 EGC31046.1 - 0.041 13.4 0.2 14 5.2 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4479) zf-C3HC4_3 PF13920.1 EGC31048.1 - 6.2e-09 35.3 7.6 1e-08 34.6 5.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31048.1 - 6.7e-08 32.0 9.8 1.9e-07 30.6 6.8 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC31048.1 - 2.4e-07 30.4 9.4 3.9e-07 29.7 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC31048.1 - 4.1e-06 26.8 5.5 1e-05 25.5 3.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC31048.1 - 1e-05 25.4 9.9 1.8e-05 24.6 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31048.1 - 0.0011 18.5 9.5 0.0021 17.7 6.6 1.5 1 0 0 1 1 1 1 zinc-RING finger domain ATP-synt_8 PF00895.15 EGC31048.1 - 0.004 17.3 2.9 0.004 17.3 2.0 4.6 3 3 2 5 5 3 1 ATP synthase protein 8 zf-C3HC4_4 PF15227.1 EGC31048.1 - 0.0079 16.0 8.2 0.025 14.4 5.7 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC31048.1 - 0.04 13.6 3.3 0.14 11.8 2.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger KaiB PF07689.7 EGC31048.1 - 0.33 10.4 3.2 0.25 10.8 0.4 2.2 2 0 0 2 2 2 0 KaiB domain DZR PF12773.2 EGC31048.1 - 0.46 10.3 7.4 4.3 7.2 5.1 2.4 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EGC31048.1 - 0.52 9.9 11.2 3.8 7.1 7.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC31048.1 - 0.63 9.9 5.2 1.5 8.7 3.6 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3430 PF11912.3 EGC31050.1 - 1.3e-34 119.9 19.6 1.3e-34 119.9 13.6 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) Serglycin PF04360.7 EGC31050.1 - 0.006 16.3 14.3 0.1 12.2 8.4 2.8 2 1 0 2 2 2 1 Serglycin Acetyltransf_1 PF00583.19 EGC31051.1 - 1.6e-12 47.2 0.0 1.1e-07 31.7 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC31051.1 - 3.9e-10 39.7 0.0 0.0002 21.4 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC31051.1 - 6.1e-07 29.5 0.4 1.5e-06 28.2 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC31051.1 - 8.7e-06 25.8 0.0 0.00039 20.5 0.0 2.4 2 2 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC31051.1 - 3.5e-05 23.9 0.0 0.1 12.7 0.0 2.4 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC31051.1 - 0.0026 17.6 0.0 0.0098 15.7 0.0 2.0 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC31051.1 - 0.0039 16.9 0.0 0.85 9.4 0.0 2.5 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_9 PF13527.1 EGC31051.1 - 0.0049 16.7 0.0 2 8.3 0.0 2.5 2 2 0 2 2 2 2 Acetyltransferase (GNAT) domain PuR_N PF09182.5 EGC31051.1 - 0.14 11.7 0.3 2.6 7.7 0.0 2.5 2 0 0 2 2 2 0 Bacterial purine repressor, N-terminal Pkinase PF00069.20 EGC31052.1 - 3.8e-17 62.3 2.4 6.5e-17 61.5 1.7 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31052.1 - 2.4e-13 49.7 0.1 4.5e-13 48.8 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGC31052.1 - 8.4e-05 22.0 0.1 0.00017 20.9 0.1 1.5 1 0 0 1 1 1 1 RIO1 family Baculo_IE-1 PF05290.6 EGC31052.1 - 0.00036 20.2 1.9 0.0013 18.4 1.3 1.9 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) APH PF01636.18 EGC31052.1 - 0.001 18.8 0.0 0.0015 18.3 0.0 1.1 1 0 0 1 1 1 1 Phosphotransferase enzyme family PIP49_C PF12260.3 EGC31052.1 - 0.022 14.1 0.1 0.022 14.1 0.0 1.6 2 0 0 2 2 2 0 Protein-kinase domain of FAM69 Kinase-like PF14531.1 EGC31052.1 - 0.095 11.6 0.0 0.15 11.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EGC31053.1 - 9.8e-23 80.6 21.5 2.1e-17 63.1 2.3 3.4 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31053.1 - 6.5e-21 74.5 3.0 2.2e-12 46.5 0.1 2.6 2 1 1 3 3 3 2 Protein tyrosine kinase RIO1 PF01163.17 EGC31053.1 - 1.8e-08 33.9 0.6 1.4e-05 24.5 0.1 2.6 2 0 0 2 2 2 2 RIO1 family APH PF01636.18 EGC31053.1 - 3.7e-05 23.5 0.0 0.00071 19.3 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGC31053.1 - 0.0011 17.9 0.0 1.4 7.8 0.0 2.4 2 0 0 2 2 2 2 Kinase-like zf-RVT PF13966.1 EGC31054.1 - 0.0024 18.1 0.4 0.0035 17.6 0.3 1.4 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Pkinase PF00069.20 EGC31055.1 - 4e-17 62.2 2.8 7.5e-17 61.3 1.9 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31055.1 - 2.2e-10 40.0 0.1 3.7e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC31055.1 - 0.00015 21.5 0.0 0.00024 20.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC31055.1 - 0.0002 20.7 0.1 0.00051 19.4 0.1 1.6 1 0 0 1 1 1 1 RIO1 family PIP49_C PF12260.3 EGC31055.1 - 0.0054 16.1 0.5 0.011 15.2 0.4 1.4 1 0 0 1 1 1 1 Protein-kinase domain of FAM69 SRI PF08236.6 EGC31055.1 - 0.07 13.0 0.5 0.07 13.0 0.4 2.3 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain Lar_restr_allev PF14354.1 EGC31055.1 - 4.5 7.6 8.2 11 6.4 4.1 2.6 3 0 0 3 3 3 0 Restriction alleviation protein Lar DUF1348 PF07080.6 EGC31057.1 - 1.3e-65 219.5 8.6 1.5e-65 219.3 5.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1348) SnoaL_2 PF12680.2 EGC31057.1 - 3.2e-06 27.4 0.1 4.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain DUF4440 PF14534.1 EGC31057.1 - 0.0021 18.2 0.0 0.0029 17.8 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) SnoaL PF07366.7 EGC31057.1 - 0.087 12.4 0.1 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 SnoaL-like polyketide cyclase SprT-like PF10263.4 EGC31058.1 - 7.2e-23 80.9 0.4 1.5e-22 79.9 0.3 1.5 1 0 0 1 1 1 1 SprT-like family HI0933_like PF03486.9 EGC31058.1 - 0.54 8.6 7.0 1.4 7.3 4.8 1.6 1 0 0 1 1 1 0 HI0933-like protein LMBR1 PF04791.11 EGC31059.1 - 0.057 12.0 1.0 0.094 11.2 0.7 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein Cyclin_C PF02984.14 EGC31059.1 - 0.086 12.7 0.7 3.2 7.6 0.0 2.7 3 0 0 3 3 3 0 Cyclin, C-terminal domain DUF2457 PF10446.4 EGC31059.1 - 0.47 9.1 9.8 0.68 8.5 6.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) RPOL_N PF14700.1 EGC31059.1 - 1.2 8.3 4.7 1.9 7.6 3.3 1.3 1 0 0 1 1 1 0 DNA-directed RNA polymerase N-terminal DUF1981 PF09324.5 EGC31060.1 - 0.051 13.1 0.3 0.32 10.5 0.0 2.3 3 0 0 3 3 3 0 Domain of unknown function (DUF1981) GST_N_3 PF13417.1 EGC31061.1 - 2.5e-09 37.2 0.0 3e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC31061.1 - 5e-09 36.2 0.0 9.9e-09 35.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC31061.1 - 2.9e-07 30.2 0.0 5.6e-07 29.3 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC31061.1 - 8.4e-07 28.9 0.0 1.5e-06 28.1 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC31061.1 - 2.8e-06 27.2 0.0 7.2e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain NmrA PF05368.8 EGC31064.1 - 9.4e-56 188.6 0.2 1.1e-55 188.3 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC31064.1 - 4.4e-08 33.3 0.0 7.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC31064.1 - 0.00072 18.3 0.0 0.0012 17.6 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family PBS_linker_poly PF00427.16 EGC31064.1 - 0.08 12.6 0.3 0.32 10.6 0.1 2.1 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Choline_transpo PF04515.7 EGC31065.1 - 4.1e-110 367.6 39.9 6.1e-110 367.0 20.9 2.8 3 0 0 3 3 3 2 Plasma-membrane choline transporter Glycophorin_A PF01102.13 EGC31065.1 - 0.14 11.8 0.6 0.38 10.5 0.4 1.7 1 0 0 1 1 1 0 Glycophorin A AAA PF00004.24 EGC31066.1 - 7.4e-45 152.3 0.0 1.9e-44 151.0 0.0 1.8 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC31066.1 - 6.4e-09 35.6 0.2 2e-08 34.0 0.1 1.8 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGC31066.1 - 1.7e-07 31.3 0.0 3.3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGC31066.1 - 6.1e-07 29.6 0.0 1.6e-06 28.2 0.0 1.6 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGC31066.1 - 9.1e-07 29.0 0.6 8e-05 22.7 0.2 2.9 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EGC31066.1 - 6.8e-05 22.0 0.0 0.00024 20.2 0.0 1.8 1 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus DUF815 PF05673.8 EGC31066.1 - 9.5e-05 21.4 0.0 0.00015 20.7 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_17 PF13207.1 EGC31066.1 - 0.00017 22.4 0.0 0.00057 20.6 0.0 1.9 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EGC31066.1 - 0.00018 20.3 0.0 0.00031 19.5 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_19 PF13245.1 EGC31066.1 - 0.00019 21.1 0.1 0.00049 19.8 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGC31066.1 - 0.00033 20.1 0.0 0.0007 19.0 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EGC31066.1 - 0.00042 20.2 0.1 0.0023 17.8 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC31066.1 - 0.00044 19.7 2.0 0.0074 15.7 0.1 2.2 1 1 1 2 2 2 1 AAA domain AAA_28 PF13521.1 EGC31066.1 - 0.00049 20.0 0.0 0.0009 19.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGC31066.1 - 0.00085 18.8 0.1 0.1 12.0 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain RNA_helicase PF00910.17 EGC31066.1 - 0.0011 19.0 0.0 0.0026 17.8 0.0 1.7 1 0 0 1 1 1 1 RNA helicase Mg_chelatase PF01078.16 EGC31066.1 - 0.0013 17.9 0.1 0.0029 16.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_18 PF13238.1 EGC31066.1 - 0.002 18.4 0.0 0.0047 17.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGC31066.1 - 0.0025 17.5 0.2 0.054 13.1 0.0 2.3 2 0 0 2 2 2 1 NACHT domain AAA_24 PF13479.1 EGC31066.1 - 0.0047 16.5 0.1 0.011 15.3 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC31066.1 - 0.0059 16.4 0.0 0.012 15.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGC31066.1 - 0.006 15.7 0.7 0.4 9.7 0.0 2.9 3 0 0 3 3 3 1 KaiC Zeta_toxin PF06414.7 EGC31066.1 - 0.008 15.2 0.0 0.015 14.4 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_3 PF07726.6 EGC31066.1 - 0.012 15.1 0.0 0.035 13.7 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_30 PF13604.1 EGC31066.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Parvo_NS1 PF01057.12 EGC31066.1 - 0.016 14.0 0.0 0.036 12.9 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 UPF0079 PF02367.12 EGC31066.1 - 0.018 14.6 0.0 0.032 13.8 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NTPase_1 PF03266.10 EGC31066.1 - 0.021 14.5 0.1 0.17 11.6 0.0 2.3 2 1 0 2 2 2 0 NTPase NB-ARC PF00931.17 EGC31066.1 - 0.025 13.4 0.2 0.098 11.4 0.0 2.0 2 0 0 2 2 2 0 NB-ARC domain Arch_ATPase PF01637.13 EGC31066.1 - 0.051 13.2 0.1 0.33 10.6 0.0 2.3 2 1 0 2 2 2 0 Archaeal ATPase AAA_11 PF13086.1 EGC31066.1 - 0.054 13.0 0.0 0.097 12.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EGC31066.1 - 0.061 13.3 0.0 0.28 11.2 0.0 2.1 2 0 0 2 2 2 0 Sigma-54 interaction domain vATP-synt_E PF01991.13 EGC31066.1 - 0.085 12.1 0.2 0.18 11.0 0.1 1.5 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit PhoH PF02562.11 EGC31066.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_10 PF12846.2 EGC31066.1 - 0.12 11.7 0.2 0.41 10.0 0.1 2.0 1 1 0 1 1 1 0 AAA-like domain CDC45 PF02724.9 EGC31067.1 - 0.019 13.0 8.0 0.02 12.9 5.2 1.2 1 1 0 1 1 1 0 CDC45-like protein NAM-associated PF14303.1 EGC31067.1 - 0.065 13.5 6.3 0.075 13.3 4.3 1.1 1 0 0 1 1 1 0 No apical meristem-associated C-terminal domain RED_N PF07808.8 EGC31067.1 - 0.066 12.4 10.7 0.079 12.1 7.4 1.1 1 0 0 1 1 1 0 RED-like protein N-terminal region Spt5_N PF11942.3 EGC31067.1 - 0.099 13.2 7.2 0.13 12.8 4.9 1.4 1 1 0 1 1 1 0 Spt5 transcription elongation factor, acidic N-terminal CENP-B_dimeris PF09026.5 EGC31067.1 - 0.14 12.4 2.5 0.19 11.9 1.7 1.3 1 0 0 1 1 1 0 Centromere protein B dimerisation domain IncA PF04156.9 EGC31067.1 - 0.29 10.6 12.8 0.37 10.3 8.9 1.1 1 0 0 1 1 1 0 IncA protein PolC_DP2 PF03833.8 EGC31067.1 - 2.7 5.5 7.0 0.27 8.8 1.7 1.5 1 1 1 2 2 2 0 DNA polymerase II large subunit DP2 FAD_binding_3 PF01494.14 EGC31068.1 - 2.4e-19 69.6 0.0 3.4e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGC31068.1 - 1.2e-09 37.5 0.2 0.00013 20.9 0.0 2.9 2 1 0 3 3 3 2 FAD dependent oxidoreductase Trp_halogenase PF04820.9 EGC31068.1 - 2.7e-09 36.1 0.0 6.3e-06 25.0 0.0 2.2 2 0 0 2 2 2 2 Tryptophan halogenase Thi4 PF01946.12 EGC31068.1 - 2.4e-05 23.5 0.1 7.8e-05 21.8 0.0 1.8 1 1 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGC31068.1 - 3.8e-05 24.0 0.2 0.00029 21.1 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC31068.1 - 4.1e-05 23.5 0.6 8.9e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGC31068.1 - 8.3e-05 21.6 0.0 0.051 12.4 0.0 2.3 2 0 0 2 2 2 2 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGC31068.1 - 0.003 17.4 0.2 0.012 15.5 0.2 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC31068.1 - 0.0041 16.2 0.0 0.0046 16.0 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGC31068.1 - 0.0052 15.2 0.0 0.013 13.9 0.0 1.7 2 0 0 2 2 2 1 HI0933-like protein FAD_binding_2 PF00890.19 EGC31068.1 - 0.0054 15.6 0.0 0.1 11.4 0.0 2.2 2 0 0 2 2 2 1 FAD binding domain SE PF08491.5 EGC31068.1 - 0.056 12.2 0.0 0.17 10.7 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase ApbA PF02558.11 EGC31068.1 - 0.086 12.2 0.1 0.23 10.8 0.0 1.8 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA Pyr_redox_3 PF13738.1 EGC31068.1 - 0.095 12.7 0.1 0.38 10.7 0.1 1.9 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase RF-1 PF00472.15 EGC31069.1 - 9.4e-34 115.6 0.2 1.5e-33 114.9 0.1 1.3 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGC31069.1 - 8.1e-28 96.4 0.1 1.8e-27 95.3 0.1 1.6 1 0 0 1 1 1 1 PCRF domain MIR PF02815.14 EGC31069.1 - 0.09 12.3 0.0 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 MIR domain GET2 PF08690.5 EGC31070.1 - 0.0086 15.3 2.2 0.01 15.1 1.3 1.3 1 1 0 1 1 1 1 GET complex subunit GET2 DUF763 PF05559.6 EGC31070.1 - 0.043 12.7 0.2 0.049 12.5 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF763) DUF3633 PF12315.3 EGC31070.1 - 0.11 11.7 0.3 0.12 11.7 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3633) Duffy_binding PF05424.6 EGC31070.1 - 0.15 11.8 6.6 0.18 11.6 4.5 1.1 1 0 0 1 1 1 0 Duffy binding domain Secretin_N_2 PF07655.8 EGC31070.1 - 0.25 11.7 6.1 0.34 11.3 4.2 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain FliE PF02049.13 EGC31070.1 - 0.33 10.9 3.4 0.76 9.8 0.1 2.0 1 1 1 2 2 2 0 Flagellar hook-basal body complex protein FliE YjbE PF11106.3 EGC31070.1 - 1 9.3 4.3 1.4 8.9 2.9 1.1 1 0 0 1 1 1 0 Exopolysaccharide production protein YjbE Takusan PF04822.8 EGC31070.1 - 7.4 6.4 9.3 0.68 9.7 2.6 2.1 2 1 1 3 3 3 0 Takusan Toxin_64 PF15542.1 EGC31071.1 - 0.032 14.8 6.3 0.035 14.6 4.3 1.1 1 0 0 1 1 1 0 Putative toxin 64 DUF2076 PF09849.4 EGC31071.1 - 0.036 14.1 2.5 0.038 14.0 1.7 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2076) FGF-BP1 PF06473.7 EGC31071.1 - 0.046 13.2 0.7 0.053 13.1 0.5 1.1 1 0 0 1 1 1 0 FGF binding protein 1 (FGF-BP1) PseudoU_synth_2 PF00849.17 EGC31072.1 - 2.2e-23 82.8 0.0 3.4e-23 82.2 0.0 1.3 1 0 0 1 1 1 1 RNA pseudouridylate synthase Pkinase PF00069.20 EGC31073.1 - 7.7e-83 277.6 0.0 8.6e-83 277.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31073.1 - 8.2e-35 120.1 0.0 1.5e-34 119.2 0.0 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC31073.1 - 9e-05 21.5 0.0 0.0031 16.5 0.0 2.4 1 1 0 2 2 2 1 Kinase-like APH PF01636.18 EGC31073.1 - 0.022 14.5 0.0 0.064 12.9 0.0 1.5 1 1 0 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC31073.1 - 0.033 13.2 0.0 0.056 12.4 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Seadorna_VP7 PF07387.6 EGC31073.1 - 0.073 11.8 0.0 0.19 10.5 0.0 1.6 2 0 0 2 2 2 0 Seadornavirus VP7 YrbL-PhoP_reg PF10707.4 EGC31073.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.3 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL TPR_11 PF13414.1 EGC31074.1 - 2.5e-37 126.3 20.1 1.1e-15 57.0 1.8 3.7 2 1 2 4 4 4 4 TPR repeat TPR_1 PF00515.23 EGC31074.1 - 5.8e-27 92.1 17.2 2.1e-09 36.6 0.1 5.2 5 0 0 5 5 5 4 Tetratricopeptide repeat DnaJ PF00226.26 EGC31074.1 - 9.7e-26 89.2 4.6 2.8e-25 87.8 3.2 1.8 1 0 0 1 1 1 1 DnaJ domain TPR_2 PF07719.12 EGC31074.1 - 1.4e-24 83.9 16.2 1.7e-07 30.5 0.1 6.4 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31074.1 - 6.5e-17 61.7 2.5 1.2e-07 32.2 0.1 3.5 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31074.1 - 2.3e-13 50.2 14.5 3.7e-05 23.9 0.3 5.6 3 2 2 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31074.1 - 3.3e-10 39.6 3.4 0.012 16.1 0.0 5.5 4 2 2 6 6 5 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31074.1 - 5.9e-10 38.5 13.8 0.0038 17.3 0.0 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31074.1 - 1.2e-09 37.2 18.7 0.00014 21.4 0.1 6.3 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31074.1 - 1.3e-07 31.3 1.4 0.016 15.0 0.0 3.2 2 1 1 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC31074.1 - 2.3e-06 27.6 11.4 0.00026 21.0 2.9 2.9 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGC31074.1 - 9.8e-06 25.4 4.4 0.0011 18.8 1.0 4.0 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31074.1 - 0.0052 16.4 2.8 1.1 9.2 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGC31074.1 - 0.62 9.3 5.8 1.6 8.0 0.1 3.5 4 0 0 4 4 4 0 SHNi-TPR Fork_head_N PF08430.7 EGC31074.1 - 0.64 10.4 14.3 0.48 10.8 8.6 1.8 2 0 0 2 2 2 0 Forkhead N-terminal region TPR_6 PF13174.1 EGC31074.1 - 1.2 9.7 17.0 2.4 8.8 0.1 5.8 6 1 1 7 7 7 0 Tetratricopeptide repeat OapA PF04225.7 EGC31075.1 - 0.031 14.1 0.1 0.17 11.8 0.0 2.3 2 0 0 2 2 2 0 Opacity-associated protein A LysM-like domain WD40 PF00400.27 EGC31076.1 - 2.7e-06 27.0 9.0 0.29 11.0 0.0 4.7 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF1510 PF07423.6 EGC31077.1 - 0.0045 16.3 32.2 0.0072 15.7 22.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) SAPS PF04499.10 EGC31077.1 - 0.0071 15.0 10.8 0.0087 14.7 7.5 1.2 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EGC31077.1 - 0.11 10.1 20.1 0.13 9.9 13.9 1.1 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EGC31077.1 - 0.14 12.1 39.5 0.28 11.1 27.4 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Borrelia_P83 PF05262.6 EGC31077.1 - 0.18 10.0 24.7 0.25 9.5 17.1 1.1 1 0 0 1 1 1 0 Borrelia P83/100 protein TT_ORF2 PF02957.10 EGC31077.1 - 0.26 12.0 10.9 0.7 10.5 7.5 1.7 1 1 0 1 1 1 0 TT viral ORF2 SprA-related PF12118.3 EGC31077.1 - 0.34 10.1 19.4 0.44 9.8 13.4 1.2 1 0 0 1 1 1 0 SprA-related family Pilt PF15453.1 EGC31077.1 - 0.36 10.4 11.7 0.52 9.9 8.1 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions Sec10 PF07393.6 EGC31077.1 - 0.38 8.8 14.9 0.46 8.5 10.3 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec10 RNA_pol_Rpb1_5 PF04998.12 EGC31077.1 - 0.83 8.8 12.7 1.3 8.2 8.8 1.2 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 DUF2201_N PF13203.1 EGC31077.1 - 1.2 8.2 13.6 1.8 7.6 9.4 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Zip PF02535.17 EGC31077.1 - 1.3 7.9 4.6 1.8 7.5 3.2 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EGC31077.1 - 1.4 6.8 23.8 1.9 6.4 16.5 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EGC31077.1 - 2.4 8.0 11.7 3.4 7.4 8.1 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FLO_LFY PF01698.11 EGC31077.1 - 3.3 6.4 18.7 5.8 5.6 13.0 1.4 1 0 0 1 1 1 0 Floricaula / Leafy protein LMBR1 PF04791.11 EGC31077.1 - 6.7 5.1 6.8 7.6 4.9 4.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein eIF-3c_N PF05470.7 EGC31077.1 - 7.6 4.4 25.3 9.6 4.1 17.5 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Ribosomal_S3_C PF00189.15 EGC31078.1 - 9.3e-17 61.0 0.1 2e-16 59.9 0.1 1.6 1 0 0 1 1 1 1 Ribosomal protein S3, C-terminal domain KH_2 PF07650.12 EGC31078.1 - 4.6e-10 38.9 0.0 7.2e-10 38.2 0.0 1.3 1 0 0 1 1 1 1 KH domain Phage_integrase PF00589.17 EGC31078.1 - 0.083 12.5 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phage integrase family eRF1_2 PF03464.10 EGC31079.1 - 9.1e-44 149.0 0.0 1.9e-43 148.0 0.0 1.5 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGC31079.1 - 1.1e-35 122.3 0.0 2.5e-35 121.1 0.0 1.6 1 0 0 1 1 1 1 eRF1 domain 3 eRF1_1 PF03463.10 EGC31079.1 - 1e-26 93.0 0.0 1.9e-26 92.2 0.0 1.3 1 0 0 1 1 1 1 eRF1 domain 1 TPR_20 PF14561.1 EGC31080.1 - 3.2e-29 100.8 0.1 1.6e-27 95.4 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat Thioredoxin PF00085.15 EGC31080.1 - 8.7e-10 38.2 0.3 4.8e-09 35.8 0.0 2.2 2 0 0 2 2 2 1 Thioredoxin TPR_19 PF14559.1 EGC31080.1 - 1.4e-09 38.1 0.4 0.015 15.6 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC31080.1 - 2.8e-05 24.1 3.1 0.002 18.2 0.4 2.6 1 1 2 3 3 3 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGC31080.1 - 4.2e-05 23.8 0.0 0.53 11.0 0.0 3.1 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31080.1 - 4.5e-05 23.9 0.0 0.01 16.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31080.1 - 0.0001 21.8 4.9 0.039 13.6 0.2 3.1 3 1 0 3 3 3 2 TPR repeat Thioredoxin_6 PF13848.1 EGC31080.1 - 0.00036 20.3 0.5 0.0012 18.6 0.3 1.9 1 0 0 1 1 1 1 Thioredoxin-like domain TPR_12 PF13424.1 EGC31080.1 - 0.0004 20.2 1.1 0.46 10.4 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31080.1 - 0.0006 19.5 8.8 0.0045 16.7 0.2 3.4 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31080.1 - 0.0009 19.5 3.7 2.9 8.5 0.1 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31080.1 - 0.0073 16.1 0.0 0.52 10.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31080.1 - 0.0095 15.6 2.3 0.0095 15.6 1.6 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat Thioredoxin_2 PF13098.1 EGC31080.1 - 0.039 14.1 0.1 0.13 12.4 0.1 2.0 1 1 0 1 1 1 0 Thioredoxin-like domain RPN7 PF10602.4 EGC31080.1 - 0.061 12.7 5.4 2.4 7.5 3.6 2.6 1 1 0 1 1 1 0 26S proteasome subunit RPN7 TPR_3 PF07720.7 EGC31080.1 - 0.079 12.7 0.7 0.25 11.1 0.5 2.0 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31080.1 - 0.12 12.3 0.0 0.73 9.8 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31080.1 - 0.17 12.1 1.2 0.88 9.9 0.2 2.8 2 0 0 2 2 1 0 Tetratricopeptide repeat IncA PF04156.9 EGC31080.1 - 7.3 6.1 9.0 0.47 10.0 0.9 2.3 2 0 0 2 2 2 0 IncA protein MBOAT PF03062.14 EGC31081.1 - 1.7e-36 125.9 41.0 1.7e-36 125.9 28.4 2.3 2 1 0 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family ATG27 PF09451.5 EGC31081.1 - 0.41 9.8 0.0 0.41 9.8 0.0 2.2 3 0 0 3 3 3 0 Autophagy-related protein 27 DUF2839 PF10999.3 EGC31081.1 - 1.8 8.6 8.5 0.19 11.7 1.4 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Pkinase PF00069.20 EGC31082.1 - 1e-77 260.7 0.0 1.2e-77 260.5 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31082.1 - 2e-34 118.8 0.0 2.4e-34 118.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC31082.1 - 5e-07 28.9 0.0 1e-05 24.6 0.0 2.0 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EGC31082.1 - 0.00011 21.9 0.0 0.11 12.1 0.0 2.1 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGC31082.1 - 0.028 13.4 0.0 0.042 12.9 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC31082.1 - 0.034 13.4 0.1 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 RIO1 family PIP5K PF01504.13 EGC31083.1 - 9.2e-75 250.9 10.9 1.4e-74 250.4 7.6 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Dynamin_M PF01031.15 EGC31084.1 - 6.5e-87 291.0 0.4 6.5e-87 291.0 0.3 2.7 3 1 1 4 4 4 1 Dynamin central region Dynamin_N PF00350.18 EGC31084.1 - 1e-54 184.8 0.0 1e-54 184.8 0.0 3.7 3 1 0 3 3 3 1 Dynamin family GED PF02212.13 EGC31084.1 - 6.6e-17 61.1 6.1 6.6e-17 61.1 4.2 3.4 2 0 0 2 2 2 1 Dynamin GTPase effector domain DUF2076 PF09849.4 EGC31084.1 - 0.00026 21.1 15.2 0.00026 21.1 10.5 1.7 2 0 0 2 2 2 1 Uncharacterized protein conserved in bacteria (DUF2076) MMR_HSR1 PF01926.18 EGC31084.1 - 0.0014 18.5 0.1 0.0014 18.5 0.1 2.7 3 1 0 3 3 3 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC31084.1 - 0.0026 17.0 0.3 0.22 10.8 0.2 2.6 2 0 0 2 2 2 1 Ferrous iron transport protein B Miro PF08477.8 EGC31084.1 - 0.011 16.2 1.0 0.052 14.0 0.0 2.8 3 0 0 3 3 3 0 Miro-like protein CBM49 PF09478.5 EGC31085.1 - 1.2e-13 50.9 1.3 1.6e-13 50.5 0.9 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC31085.1 - 0.0072 16.2 5.1 0.12 12.2 0.3 2.4 2 0 0 2 2 2 2 DIM protein PI3_PI4_kinase PF00454.22 EGC31088.1 - 1.2e-47 162.3 0.9 1.2e-47 162.3 0.6 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FATC PF02260.15 EGC31088.1 - 2.9e-12 45.7 0.1 6.8e-12 44.6 0.1 1.7 1 0 0 1 1 1 1 FATC domain HEAT_2 PF13646.1 EGC31088.1 - 0.068 13.4 0.0 1.1 9.5 0.0 3.0 3 0 0 3 3 3 0 HEAT repeats CgtA PF06306.6 EGC31089.1 - 0.014 14.6 2.8 0.014 14.5 2.0 1.0 1 0 0 1 1 1 0 Beta-1,4-N-acetylgalactosaminyltransferase (CgtA) Phage_int_SAM_5 PF13102.1 EGC31089.1 - 0.021 14.8 1.6 0.036 14.0 0.2 1.8 1 1 1 2 2 2 0 Phage integrase SAM-like domain DUF2600 PF10776.4 EGC31090.1 - 0.041 12.7 0.1 0.046 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2600) ArfGap PF01412.13 EGC31091.1 - 7.1e-40 135.4 0.0 2.8e-39 133.5 0.0 2.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf PH PF00169.24 EGC31091.1 - 2.2e-22 79.2 6.3 2.6e-14 53.2 1.4 2.8 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EGC31091.1 - 4.3e-09 36.6 13.0 1.8e-06 28.1 2.0 3.5 2 1 1 3 3 3 2 Pleckstrin homology domain Mcp5_PH PF12814.2 EGC31091.1 - 0.0017 18.2 0.9 0.0017 18.2 0.6 2.5 2 0 0 2 2 2 1 Meiotic cell cortex C-terminal pleckstrin homology PH_9 PF15410.1 EGC31091.1 - 0.073 13.2 2.5 12 6.0 0.6 2.8 2 1 0 2 2 2 0 Pleckstrin homology domain RabGAP-TBC PF00566.13 EGC31092.1 - 2e-38 132.0 4.4 1.3e-35 122.8 3.1 2.4 1 1 0 1 1 1 1 Rab-GTPase-TBC domain Glyco_transf_10 PF00852.14 EGC31093.1 - 1.1e-46 159.0 10.1 3.9e-46 157.2 7.0 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Pkinase_Tyr PF07714.12 EGC31095.1 - 9.1e-55 185.5 0.0 1.8e-54 184.5 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC31095.1 - 1.2e-54 185.1 0.0 1.2e-54 185.1 0.0 2.6 3 1 0 3 3 3 1 Protein kinase domain APH PF01636.18 EGC31095.1 - 0.048 13.3 0.2 0.1 12.3 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family CLPTM1 PF05602.7 EGC31096.1 - 6.8e-129 430.4 8.7 6.8e-129 430.4 6.0 1.6 2 0 0 2 2 2 1 Cleft lip and palate transmembrane protein 1 (CLPTM1) PQ-loop PF04193.9 EGC31096.1 - 0.0017 17.8 10.0 0.029 13.9 0.5 3.2 3 1 0 3 3 3 2 PQ loop repeat Pox_Ag35 PF03286.9 EGC31096.1 - 0.41 10.1 15.2 0.63 9.5 10.5 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Peptidase_S49_N PF08496.5 EGC31096.1 - 2.6 7.8 7.1 5.3 6.8 4.9 1.5 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CobT PF06213.7 EGC31096.1 - 6 5.9 15.5 8.6 5.4 10.8 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT PBP1_TM PF14812.1 EGC31096.1 - 7.5 6.9 15.0 16 5.8 10.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF2435 PF10363.4 EGC31098.1 - 2.8e-24 84.8 3.7 7.4e-24 83.4 0.0 3.2 4 0 0 4 4 4 1 Protein of unknown function (DUF2435) DUF2411 PF10304.4 EGC31098.1 - 2e-08 33.5 0.1 5.7e-08 32.0 0.1 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF2411) HEAT PF02985.17 EGC31098.1 - 0.00038 20.3 0.0 0.67 10.1 0.0 3.8 4 0 0 4 4 4 2 HEAT repeat Cnd1 PF12717.2 EGC31098.1 - 0.00062 19.6 2.1 0.89 9.3 0.0 3.4 2 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGC31098.1 - 0.0012 19.1 0.0 1.6 9.2 0.0 3.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EGC31098.1 - 0.037 14.3 0.0 6.3 7.1 0.0 2.7 1 1 2 3 3 3 0 HEAT repeats Pkinase PF00069.20 EGC31099.1 - 1.9e-62 210.7 0.2 3.1e-61 206.7 0.2 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31099.1 - 1.1e-27 96.6 0.4 1.7e-19 69.9 0.1 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Pkinase_C PF00433.19 EGC31099.1 - 8e-07 29.4 2.8 1.7e-06 28.4 1.9 1.6 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGC31099.1 - 0.00031 19.8 0.1 0.0046 15.9 0.0 2.5 3 0 0 3 3 3 1 Kinase-like APH PF01636.18 EGC31099.1 - 0.00055 19.7 0.1 0.38 10.4 0.1 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC31099.1 - 0.0071 15.2 0.1 0.024 13.4 0.0 1.9 2 0 0 2 2 2 1 Seadornavirus VP7 CLIP PF12032.3 EGC31099.1 - 0.0072 16.3 0.1 0.019 15.0 0.1 1.6 1 0 0 1 1 1 1 Regulatory CLIP domain of proteinases Fungal_trans_2 PF11951.3 EGC31099.1 - 0.14 10.7 1.3 1.1 7.7 0.0 2.1 2 0 0 2 2 2 0 Fungal specific transcription factor domain Coiled PF05710.7 EGC31100.1 - 0.27 11.7 5.9 0.33 11.4 4.1 1.1 1 0 0 1 1 1 0 Coiled coil PseudoU_synth_2 PF00849.17 EGC31101.1 - 1.1e-10 41.6 0.0 1.1e-10 41.6 0.0 3.6 2 2 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 EGC31101.1 - 0.00034 19.9 0.0 0.0062 15.9 0.0 2.6 1 1 1 2 2 2 1 S4 domain Meiosis_expr PF15163.1 EGC31101.1 - 2.2 8.7 8.5 2.2 8.7 0.6 2.7 2 0 0 2 2 2 0 Meiosis-expressed Hpt PF01627.18 EGC31102.1 - 2.3e-11 43.5 0.0 3.7e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Hpt domain SPX PF03105.14 EGC31102.1 - 0.00014 21.7 15.4 0.00016 21.5 10.7 1.2 1 0 0 1 1 1 1 SPX domain PPR PF01535.15 EGC31102.1 - 0.072 13.1 0.0 0.18 11.8 0.0 1.7 1 1 0 1 1 1 0 PPR repeat DUF2203 PF09969.4 EGC31102.1 - 4.5 7.5 7.0 47 4.2 4.1 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) SEC-C PF02810.10 EGC31103.1 - 1.7e-05 24.1 6.1 2.8e-05 23.5 4.2 1.4 1 0 0 1 1 1 1 SEC-C motif Eaf7 PF07904.8 EGC31106.1 - 2.5e-09 36.9 0.1 2.5e-09 36.9 0.1 1.6 2 0 0 2 2 2 1 Chromatin modification-related protein EAF7 Methyltransf_12 PF08242.7 EGC31106.1 - 0.063 13.7 0.1 0.097 13.1 0.1 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pex14_N PF04695.8 EGC31106.1 - 0.076 13.0 0.3 0.1 12.6 0.2 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region HEAT PF02985.17 EGC31107.1 - 3.6e-05 23.4 0.1 0.00022 21.0 0.0 2.5 2 0 0 2 2 2 1 HEAT repeat Arm PF00514.18 EGC31107.1 - 0.0011 18.6 0.1 0.052 13.3 0.1 2.9 2 0 0 2 2 2 1 Armadillo/beta-catenin-like repeat Fes1 PF08609.5 EGC31107.1 - 0.0023 18.4 6.4 0.0031 17.9 2.6 2.5 2 1 0 2 2 2 1 Nucleotide exchange factor Fes1 HEAT_2 PF13646.1 EGC31107.1 - 0.01 16.0 0.0 0.1 12.8 0.0 2.5 3 0 0 3 3 3 0 HEAT repeats HEAT_EZ PF13513.1 EGC31107.1 - 0.17 12.4 0.0 0.54 10.8 0.0 1.9 2 0 0 2 2 2 0 HEAT-like repeat Glyco_transf_10 PF00852.14 EGC31108.1 - 1.7e-46 158.3 8.3 1.4e-45 155.3 5.7 1.9 1 1 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Actin PF00022.14 EGC31109.1 - 2.7e-91 305.9 0.0 3.9e-91 305.4 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC31109.1 - 0.0067 15.0 0.0 2.4 6.6 0.0 2.1 2 0 0 2 2 2 2 MreB/Mbl protein NDT80_PhoG PF05224.7 EGC31110.1 - 3.4e-23 82.5 0.4 3.4e-23 82.5 0.2 4.0 3 2 0 3 3 3 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 EGC31110.1 - 1e-09 38.3 0.1 2.1e-09 37.3 0.0 1.6 1 0 0 1 1 1 1 Chaperone of endosialidase CCDC-167 PF15188.1 EGC31110.1 - 0.007 16.2 0.4 0.02 14.8 0.3 1.8 1 0 0 1 1 1 1 Coiled-coil domain-containing protein 167 DUF1212 PF06738.7 EGC31110.1 - 0.0094 15.4 0.2 0.021 14.3 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1212) MRF_C1 PF13887.1 EGC31110.1 - 0.014 14.4 0.1 0.026 13.5 0.1 1.3 1 0 0 1 1 1 0 Myelin gene regulatory factor -C-terminal domain 1 DUF2615 PF11027.3 EGC31110.1 - 0.057 13.3 0.3 0.057 13.3 0.2 3.1 4 0 0 4 4 4 0 Protein of unknown function (DUF2615) DUF2238 PF09997.4 EGC31110.1 - 0.077 12.3 1.5 0.078 12.3 0.1 1.6 2 0 0 2 2 2 0 Predicted membrane protein (DUF2238) DUF607 PF04678.8 EGC31110.1 - 0.11 12.4 0.7 0.3 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF607 DUF2204 PF09970.4 EGC31110.1 - 0.17 11.3 1.2 0.29 10.6 0.8 1.3 1 0 0 1 1 1 0 Nucleotidyl transferase of unknown function (DUF2204) DUF4179 PF13786.1 EGC31111.1 - 0.18 12.0 0.2 0.18 12.0 0.1 5.1 4 2 1 6 6 6 0 Domain of unknown function (DUF4179) GTP_EFTU PF00009.22 EGC31114.1 - 3.9e-49 166.6 0.0 9e-49 165.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGC31114.1 - 4.7e-17 61.9 0.0 5.3e-16 58.6 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D4 PF14578.1 EGC31114.1 - 2.2e-06 27.2 0.1 4.3e-06 26.2 0.1 1.5 1 0 0 1 1 1 1 Elongation factor Tu domain 4 GTP_EFTU_D2 PF03144.20 EGC31114.1 - 0.00016 21.7 0.1 0.00083 19.4 0.1 2.3 1 0 0 1 1 1 1 Elongation factor Tu domain 2 HBS1_N PF08938.5 EGC31114.1 - 0.00054 20.0 9.7 0.00054 20.0 6.7 2.1 2 0 0 2 2 2 1 HBS1 N-terminus CUE PF02845.11 EGC31114.1 - 0.0027 17.1 0.5 0.0072 15.7 0.3 1.8 1 0 0 1 1 1 1 CUE domain DUF1219 PF06755.7 EGC31114.1 - 0.043 13.3 0.1 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1219) Complex1_LYR PF05347.10 EGC31116.1 - 3.5e-06 26.7 1.5 1.8e-05 24.4 0.1 2.4 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC31116.1 - 4.6e-05 23.5 1.5 0.00015 21.8 0.1 2.3 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGC31116.1 - 0.00055 20.3 0.2 0.00083 19.7 0.1 1.3 1 0 0 1 1 1 1 Complex1_LYR-like PH PF00169.24 EGC31117.1 - 1.1e-09 38.4 1.2 5.4e-09 36.1 0.8 2.2 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC31117.1 - 9.8e-06 25.7 1.0 9.8e-06 25.7 0.7 2.7 3 0 0 3 3 3 1 Pleckstrin homology domain WD40 PF00400.27 EGC31117.1 - 0.046 13.6 2.6 0.36 10.7 0.1 3.4 3 0 0 3 3 3 0 WD domain, G-beta repeat CBM49 PF09478.5 EGC31118.1 - 2.4e-05 24.3 0.1 0.00017 21.6 0.0 2.0 1 1 1 2 2 2 1 Carbohydrate binding domain CBM49 Tachystatin_B PF11478.3 EGC31118.1 - 0.33 10.7 4.2 0.81 9.4 2.9 1.6 1 0 0 1 1 1 0 Antimicrobial chitin binding protein tachystatin B Sds3 PF08598.6 EGC31119.1 - 2.1e-23 82.9 22.8 2.1e-23 82.9 15.8 4.8 2 2 1 3 3 3 1 Sds3-like Eapp_C PF10238.4 EGC31120.1 - 0.099 12.5 12.7 0.19 11.6 8.8 1.5 1 0 0 1 1 1 0 E2F-associated phosphoprotein DUF912 PF06024.7 EGC31120.1 - 3.1 7.9 15.5 28 4.8 9.2 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PAN_3 PF08277.7 EGC31121.1 - 0.031 13.9 2.3 0.43 10.2 0.5 2.5 2 0 0 2 2 2 0 PAN-like domain MMgT PF10270.4 EGC31121.1 - 0.034 14.5 0.8 0.18 12.2 0.0 2.5 2 1 1 3 3 3 0 Membrane magnesium transporter RhoGEF PF00621.15 EGC31122.1 - 4.1e-45 153.8 2.0 4.1e-45 153.8 1.4 2.2 2 1 0 2 2 2 1 RhoGEF domain PH PF00169.24 EGC31122.1 - 1.1e-06 28.7 1.0 2.9e-06 27.4 0.0 2.3 2 1 0 2 2 2 1 PH domain ETRAMP PF09716.5 EGC31123.1 - 8.8 6.3 13.5 1.7e+02 2.2 9.3 2.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) NuA4 PF09340.5 EGC31124.1 - 8.2e-25 86.2 1.2 8.2e-25 86.2 0.8 3.1 2 1 0 2 2 2 1 Histone acetyltransferase subunit NuA4 MIP-T3 PF10243.4 EGC31124.1 - 2.7e-05 22.8 38.7 2.9e-05 22.7 26.8 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EGC31124.1 - 0.019 13.4 30.9 0.02 13.3 21.4 1.2 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGC31124.1 - 0.32 8.9 30.6 0.43 8.5 21.2 1.2 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 EGC31124.1 - 2.5 6.4 14.6 3.1 6.1 10.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Nop14 PF04147.7 EGC31124.1 - 3.1 5.6 49.0 4.6 5.0 33.9 1.3 1 0 0 1 1 1 0 Nop14-like family DUF4175 PF13779.1 EGC31124.1 - 3.2 5.3 20.5 4.1 4.9 14.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) PLRV_ORF5 PF01690.12 EGC31124.1 - 3.4 6.6 26.4 4.5 6.2 18.3 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Merozoite_SPAM PF07133.6 EGC31124.1 - 5.7 6.8 60.2 13 5.6 41.7 1.6 1 1 0 1 1 1 0 Merozoite surface protein (SPAM) LRR_6 PF13516.1 EGC31125.1 - 2.1e-11 42.6 40.8 0.015 15.2 0.1 13.2 14 0 0 14 14 14 3 Leucine Rich repeat LRR_8 PF13855.1 EGC31125.1 - 1.1e-06 28.2 33.4 0.077 12.7 0.4 8.1 5 2 4 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 EGC31125.1 - 3.7e-06 26.2 34.5 5.3 7.4 0.0 13.3 13 1 0 13 13 13 2 Leucine Rich Repeat LRR_4 PF12799.2 EGC31125.1 - 6.8e-05 22.3 35.7 0.013 15.1 0.1 8.3 5 3 5 10 10 10 5 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGC31125.1 - 0.0063 16.5 21.5 11 6.7 0.0 9.4 10 0 0 10 10 10 2 Leucine rich repeat TetR_C_4 PF08359.6 EGC31126.1 - 0.085 12.7 2.7 0.17 11.7 0.1 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Zip PF02535.17 EGC31126.1 - 1.5 7.7 3.1 1.9 7.4 2.1 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter RRM_1 PF00076.17 EGC31127.1 - 6e-18 64.2 0.1 9.4e-18 63.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31127.1 - 3.4e-14 52.5 0.0 5.1e-14 52.0 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31127.1 - 1e-11 44.4 0.0 1.8e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC31127.1 - 0.0019 18.0 0.0 0.0028 17.4 0.0 1.4 1 0 0 1 1 1 1 RNA binding motif Profilin PF00235.14 EGC31128.1 - 1e-22 80.4 0.0 1.1e-22 80.3 0.0 1.0 1 0 0 1 1 1 1 Profilin Profilin PF00235.14 EGC31129.1 - 1.8e-15 57.1 0.0 2e-15 56.9 0.0 1.0 1 0 0 1 1 1 1 Profilin CENP-T PF15511.1 EGC31130.1 - 2 7.5 21.2 2.2 7.4 14.7 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T alpha-hel2 PF14456.1 EGC31130.1 - 2.5 6.7 15.0 3.9 6.1 10.4 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 SUR7 PF06687.7 EGC31131.1 - 0.00021 20.9 9.0 0.00021 20.9 6.3 2.7 2 1 1 3 3 3 1 SUR7/PalI family DUF4231 PF14015.1 EGC31131.1 - 6.1 6.8 10.4 12 5.9 0.1 3.0 2 1 0 3 3 3 0 Protein of unknown function (DUF4231) Ribosomal_L22 PF00237.14 EGC31133.1 - 1.9e-28 98.5 0.2 2.3e-28 98.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L22p/L17e ABC_tran PF00005.22 EGC31134.1 - 3.5e-46 156.8 12.9 7.9e-23 81.2 0.0 4.0 3 1 1 4 4 4 2 ABC transporter ABC_tran_2 PF12848.2 EGC31134.1 - 1.4e-25 88.9 5.4 1.4e-25 88.9 3.7 3.0 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 EGC31134.1 - 2.2e-13 50.8 12.9 0.0005 20.1 0.4 4.8 2 2 2 4 4 4 4 AAA domain AAA_17 PF13207.1 EGC31134.1 - 1.4e-08 35.6 5.9 0.006 17.4 0.0 4.3 4 1 0 4 4 3 2 AAA domain SMC_N PF02463.14 EGC31134.1 - 3.8e-07 29.5 2.7 0.049 12.8 0.0 3.6 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EGC31134.1 - 6.6e-07 29.1 0.1 0.022 14.4 0.0 2.7 2 0 0 2 2 2 2 NACHT domain AAA_22 PF13401.1 EGC31134.1 - 6.8e-07 29.4 0.4 0.013 15.6 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA PF00004.24 EGC31134.1 - 7.5e-07 29.4 0.0 0.048 13.8 0.0 3.8 3 1 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EGC31134.1 - 3e-06 27.7 0.0 0.11 13.0 0.0 2.8 2 0 0 2 2 2 2 Miro-like protein AAA_29 PF13555.1 EGC31134.1 - 5.6e-06 25.7 0.4 0.022 14.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_23 PF13476.1 EGC31134.1 - 1.2e-05 25.7 20.2 0.041 14.2 0.1 4.1 3 1 0 3 3 3 2 AAA domain MobB PF03205.9 EGC31134.1 - 4.1e-05 23.2 0.2 0.21 11.2 0.1 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B cobW PF02492.14 EGC31134.1 - 4.6e-05 22.9 2.2 0.13 11.6 0.0 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain PduV-EutP PF10662.4 EGC31134.1 - 5.2e-05 22.7 0.3 0.39 10.1 0.1 2.6 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_14 PF13173.1 EGC31134.1 - 0.0001 22.2 0.0 1.1 9.1 0.0 3.5 3 0 0 3 3 3 2 AAA domain MMR_HSR1 PF01926.18 EGC31134.1 - 0.00016 21.6 0.1 0.32 10.9 0.0 3.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC31134.1 - 0.00017 20.8 0.1 0.21 10.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_5 PF07728.9 EGC31134.1 - 0.00029 20.5 0.8 1 9.0 0.0 3.6 4 0 0 4 4 3 2 AAA domain (dynein-related subfamily) AAA_10 PF12846.2 EGC31134.1 - 0.00031 20.2 4.0 1.4 8.3 0.0 3.8 3 1 0 3 3 3 2 AAA-like domain AAA_19 PF13245.1 EGC31134.1 - 0.00059 19.5 0.2 0.65 9.7 0.0 2.8 2 0 0 2 2 2 1 Part of AAA domain T2SE PF00437.15 EGC31134.1 - 0.00061 18.7 0.1 0.37 9.6 0.0 2.6 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EGC31134.1 - 0.00062 19.2 0.0 0.37 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC31134.1 - 0.00064 19.7 3.6 0.42 10.5 0.2 3.4 3 1 0 3 3 3 2 AAA ATPase domain AAA_24 PF13479.1 EGC31134.1 - 0.00081 19.0 0.8 1.1 8.8 0.0 3.1 3 0 0 3 3 3 1 AAA domain UPF0079 PF02367.12 EGC31134.1 - 0.0012 18.4 0.8 0.38 10.3 0.1 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NB-ARC PF00931.17 EGC31134.1 - 0.0016 17.3 0.0 0.75 8.5 0.0 2.4 2 0 0 2 2 2 1 NB-ARC domain Zeta_toxin PF06414.7 EGC31134.1 - 0.0017 17.4 2.9 0.054 12.5 0.0 3.2 3 0 0 3 3 3 1 Zeta toxin RNA_helicase PF00910.17 EGC31134.1 - 0.0018 18.4 0.0 0.81 9.8 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_33 PF13671.1 EGC31134.1 - 0.002 18.0 8.1 0.18 11.6 0.0 4.0 4 1 0 4 4 4 1 AAA domain AAA_28 PF13521.1 EGC31134.1 - 0.0028 17.6 9.6 0.15 12.0 0.1 3.0 4 0 0 4 4 2 2 AAA domain SRP54 PF00448.17 EGC31134.1 - 0.004 16.6 0.4 1.3 8.4 0.1 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain NTPase_1 PF03266.10 EGC31134.1 - 0.0052 16.5 0.1 1.4 8.5 0.0 2.7 2 0 0 2 2 2 1 NTPase DUF3584 PF12128.3 EGC31134.1 - 0.0068 13.8 0.3 0.0068 13.8 0.2 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF3584) AAA_15 PF13175.1 EGC31134.1 - 0.0074 15.3 21.9 0.075 12.0 0.0 5.2 3 1 3 6 6 6 1 AAA ATPase domain SbcCD_C PF13558.1 EGC31134.1 - 0.012 15.5 0.2 1.4 8.8 0.0 3.4 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_18 PF13238.1 EGC31134.1 - 0.02 15.1 17.1 0.15 12.4 0.0 4.5 4 2 0 4 4 2 0 AAA domain Arf PF00025.16 EGC31134.1 - 0.033 13.4 0.6 0.87 8.8 0.1 2.6 2 0 0 2 2 2 0 ADP-ribosylation factor family Pox_A32 PF04665.7 EGC31134.1 - 0.038 13.2 4.2 0.56 9.4 0.1 3.1 2 1 1 3 3 3 0 Poxvirus A32 protein ATP-synt_ab PF00006.20 EGC31134.1 - 0.054 12.9 0.0 3 7.2 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Dynamin_N PF00350.18 EGC31134.1 - 0.11 12.2 5.7 2.6 7.8 0.1 3.9 4 0 0 4 4 4 0 Dynamin family Arch_ATPase PF01637.13 EGC31134.1 - 0.18 11.4 8.8 0.66 9.6 0.0 3.7 4 0 0 4 4 4 0 Archaeal ATPase AAA_30 PF13604.1 EGC31134.1 - 0.22 11.0 6.7 2.9 7.4 0.1 3.0 3 1 0 3 3 2 0 AAA domain Thymidylate_kin PF02223.12 EGC31134.1 - 5.5 6.3 9.6 6.4 6.1 0.0 3.7 4 0 0 4 4 3 0 Thymidylate kinase FNIP PF05725.7 EGC31136.1 - 9.5e-36 121.5 28.1 1.4e-11 44.1 1.1 4.7 4 0 0 4 4 4 4 FNIP Repeat UPF0121 PF03661.8 EGC31136.1 - 5.8e-15 55.1 14.4 9e-15 54.5 10.0 1.2 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0121) FNIP PF05725.7 EGC31137.1 - 1.7e-75 248.7 56.0 4.5e-13 48.9 0.1 11.6 5 3 6 12 12 12 12 FNIP Repeat DUF3548 PF12068.3 EGC31138.1 - 9.3e-50 168.8 0.7 9.3e-50 168.8 0.5 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3548) RabGAP-TBC PF00566.13 EGC31138.1 - 8.5e-41 139.7 11.0 8.5e-41 139.7 7.6 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain ADH_zinc_N PF00107.21 EGC31139.1 - 1.4e-16 60.2 0.0 2.1e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC31139.1 - 0.00034 21.5 0.0 0.00071 20.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acetyltransf_1 PF00583.19 EGC31141.1 - 5.4e-17 61.6 0.0 7.4e-17 61.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC31141.1 - 4.3e-09 36.4 0.1 8e-09 35.5 0.0 1.4 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC31141.1 - 6.5e-09 35.4 0.1 1e-08 34.8 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_8 PF13523.1 EGC31141.1 - 3.8e-06 26.8 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC31141.1 - 0.00016 21.7 0.0 0.00021 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC31141.1 - 0.00046 20.1 0.1 0.00054 19.9 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC31141.1 - 0.00085 19.1 0.0 0.0011 18.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC31141.1 - 0.0016 18.6 0.0 0.0018 18.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_13 PF13880.1 EGC31141.1 - 0.14 11.8 0.0 0.25 11.1 0.0 1.4 1 0 0 1 1 1 0 ESCO1/2 acetyl-transferase MetW PF07021.7 EGC31143.1 - 0.092 12.1 0.1 0.95 8.8 0.0 2.0 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW Palm_thioest PF02089.10 EGC31144.1 - 2.3e-21 75.9 0.1 2.8e-21 75.7 0.1 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase DUF676 PF05057.9 EGC31144.1 - 1.1e-05 24.9 0.0 1.5e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EGC31144.1 - 5.1e-05 22.9 0.0 7.3e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC31144.1 - 0.0006 19.7 0.0 0.00062 19.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF3089 PF11288.3 EGC31144.1 - 0.011 14.9 0.1 0.017 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3089) Abhydrolase_5 PF12695.2 EGC31144.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Clathrin PF00637.15 EGC31144.1 - 0.052 13.1 0.1 0.089 12.3 0.0 1.3 1 0 0 1 1 1 0 Region in Clathrin and VPS FSH1 PF03959.8 EGC31144.1 - 0.1 12.0 0.1 0.31 10.4 0.0 1.7 1 1 0 1 1 1 0 Serine hydrolase (FSH1) TPR_11 PF13414.1 EGC31145.1 - 6e-10 38.6 0.8 2.5e-06 27.0 0.1 2.5 1 1 2 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGC31145.1 - 7.9e-10 37.9 0.5 2.9e-05 23.4 0.1 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31145.1 - 4.3e-08 32.4 0.3 0.0003 20.4 0.0 3.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31145.1 - 1.7e-05 24.6 1.4 0.032 14.1 0.0 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31145.1 - 0.003 17.6 0.4 0.21 11.8 0.0 3.4 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31145.1 - 0.0079 15.9 1.9 0.042 13.6 0.5 2.7 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31145.1 - 0.0094 15.6 0.1 0.055 13.2 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31145.1 - 0.034 14.8 0.0 0.095 13.4 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF676 PF05057.9 EGC31146.1 - 1.9e-39 135.2 4.1 2.7e-39 134.7 0.4 2.4 2 1 0 2 2 2 1 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGC31146.1 - 7e-07 29.0 0.0 1.8e-06 27.7 0.0 1.7 1 1 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EGC31146.1 - 5.8e-05 22.7 0.0 0.00013 21.6 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGC31146.1 - 5.8e-05 22.8 0.0 7.9e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EGC31146.1 - 7.9e-05 21.7 0.6 0.00034 19.6 0.0 2.1 1 1 1 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EGC31146.1 - 0.00046 19.5 0.4 0.0011 18.3 0.0 1.8 2 0 0 2 2 2 1 Lipase (class 2) Polysacc_syn_2C PF08485.5 EGC31146.1 - 0.19 11.2 0.1 0.19 11.2 0.1 2.0 2 0 0 2 2 2 0 Polysaccharide biosynthesis protein C-terminal FMO-like PF00743.14 EGC31147.1 - 3.4e-58 197.1 5.9 4.9e-58 196.6 4.1 1.2 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGC31147.1 - 2.7e-16 60.2 0.0 4.2e-16 59.6 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC31147.1 - 2.1e-07 31.0 0.0 7.9e-07 29.1 0.0 2.0 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC31147.1 - 2.4e-06 26.7 1.3 1.3e-05 24.3 0.1 2.6 3 1 0 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_9 PF13454.1 EGC31147.1 - 0.0011 18.8 0.0 0.014 15.1 0.0 2.5 2 0 0 2 2 2 1 FAD-NAD(P)-binding NAD_binding_8 PF13450.1 EGC31147.1 - 0.012 15.6 0.0 0.025 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Arm PF00514.18 EGC31148.1 - 1.9e-05 24.2 0.1 2.2 8.2 0.0 5.7 6 0 0 6 6 6 2 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC31148.1 - 0.0013 18.9 0.2 0.053 13.8 0.0 3.7 5 0 0 5 5 5 1 HEAT repeats WD40 PF00400.27 EGC31149.1 - 3.3e-32 109.1 19.7 1.2e-07 31.3 0.1 8.1 8 0 0 8 8 8 7 WD domain, G-beta repeat Bromodomain PF00439.20 EGC31149.1 - 3.4e-13 49.3 0.7 1.4e-12 47.2 0.5 2.2 1 0 0 1 1 1 1 Bromodomain Auxin_resp PF06507.8 EGC31149.1 - 6.2e-05 22.7 0.0 0.00019 21.2 0.0 1.8 1 0 0 1 1 1 1 Auxin response factor DUF3439 PF11921.3 EGC31149.1 - 0.0038 16.9 3.4 0.0038 16.9 2.4 3.8 3 0 0 3 3 3 1 Domain of unknown function (DUF3439) Nepo_coat_C PF03688.9 EGC31150.1 - 0.062 12.9 0.1 0.14 11.7 0.1 1.5 1 0 0 1 1 1 0 Nepovirus coat protein, C-terminal domain Rap_GAP PF02145.10 EGC31151.1 - 1.8e-65 219.8 9.0 1.8e-65 219.8 6.2 2.9 3 1 0 3 3 3 1 Rap/ran-GAP FNIP PF05725.7 EGC31152.1 - 2.3e-107 350.7 54.5 6.7e-17 61.1 1.0 9.1 6 1 4 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 EGC31152.1 - 0.029 14.3 21.6 5.5 7.0 0.1 8.3 4 3 4 9 9 9 0 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC31153.1 - 6.7e-96 314.0 40.8 2.8e-15 55.9 0.1 10.6 9 1 0 10 10 10 8 FNIP Repeat zf-B_box PF00643.19 EGC31153.1 - 0.00052 19.8 4.9 0.00086 19.1 3.4 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC31153.1 - 0.17 11.5 2.8 0.33 10.7 1.9 1.3 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Oxidored_FMN PF00724.15 EGC31154.1 - 5.7e-77 259.0 0.0 7e-77 258.7 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGC31154.1 - 0.021 13.6 0.0 0.061 12.1 0.0 1.7 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Pkinase PF00069.20 EGC31155.1 - 5e-66 222.5 3.7 9.9e-42 142.8 0.4 3.1 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31155.1 - 1.8e-31 109.1 0.0 9e-24 83.9 0.1 2.3 2 0 0 2 2 2 2 Protein tyrosine kinase PX PF00787.19 EGC31155.1 - 5.7e-21 74.4 1.3 1.5e-20 73.0 0.3 2.3 2 0 0 2 2 2 1 PX domain PH PF00169.24 EGC31155.1 - 2.3e-16 59.8 0.0 2.3e-16 59.8 0.0 3.9 4 0 0 4 4 4 1 PH domain Kinase-like PF14531.1 EGC31155.1 - 2.6e-05 23.3 0.0 0.002 17.1 0.0 2.4 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.1 EGC31155.1 - 0.0018 18.5 4.7 0.0026 18.0 0.2 3.6 2 1 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EGC31155.1 - 0.0022 18.0 0.0 0.0081 16.2 0.0 2.0 1 1 0 1 1 1 1 Pleckstrin homology domain TyeA PF09059.5 EGC31155.1 - 0.01 15.7 0.2 0.025 14.4 0.2 1.7 1 0 0 1 1 1 0 TyeA APH PF01636.18 EGC31155.1 - 0.012 15.3 0.0 0.021 14.5 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1084 PF06454.6 EGC31156.1 - 6.4e-24 84.4 10.6 1.9e-15 56.6 5.2 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1084) ABC2_membrane PF01061.19 EGC31159.1 - 9.2e-79 263.4 57.1 1.2e-44 152.0 17.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC31159.1 - 1.1e-38 132.6 0.7 6.8e-18 65.2 0.0 2.9 3 0 0 3 3 2 2 ABC transporter PDR_CDR PF06422.7 EGC31159.1 - 2.2e-29 101.1 3.0 3.9e-19 68.2 0.0 2.7 2 0 0 2 2 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGC31159.1 - 6.2e-09 35.8 1.1 2.8e-08 33.7 0.8 2.1 1 1 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EGC31159.1 - 9.6e-07 28.1 0.0 0.00031 19.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC31159.1 - 8.8e-06 25.1 0.1 0.0031 17.0 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC2_membrane_3 PF12698.2 EGC31159.1 - 9.8e-06 24.8 60.4 0.00012 21.3 8.1 4.0 3 1 0 3 3 3 2 ABC-2 family transporter protein AAA_25 PF13481.1 EGC31159.1 - 0.0002 20.8 0.0 0.0028 17.0 0.1 2.6 3 0 0 3 3 3 1 AAA domain AAA_22 PF13401.1 EGC31159.1 - 0.00025 21.1 0.1 0.15 12.2 0.1 3.0 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EGC31159.1 - 0.0053 16.2 0.2 0.094 12.1 0.0 2.2 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EGC31159.1 - 0.0064 16.7 0.2 4.5 7.4 0.1 3.2 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EGC31159.1 - 0.0069 16.3 0.0 5.4 7.0 0.0 2.8 3 0 0 3 3 2 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGC31159.1 - 0.0077 16.2 0.0 0.67 9.9 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGC31159.1 - 0.0096 16.7 0.9 0.35 11.6 0.0 2.9 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EGC31159.1 - 0.023 14.6 0.0 0.071 13.0 0.0 5.4 5 1 0 5 5 3 0 AAA domain UPF0079 PF02367.12 EGC31159.1 - 0.033 13.8 0.3 0.64 9.6 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 SbcCD_C PF13558.1 EGC31159.1 - 0.034 14.0 0.0 0.2 11.5 0.0 2.2 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGC31159.1 - 0.037 13.8 0.0 0.25 11.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGC31159.1 - 0.073 12.1 0.0 1.3 8.0 0.0 2.2 2 0 0 2 2 2 0 Zeta toxin PduV-EutP PF10662.4 EGC31159.1 - 0.079 12.4 0.4 0.99 8.8 0.1 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation Miro PF08477.8 EGC31159.1 - 0.083 13.3 0.0 2.4 8.6 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein AAA_30 PF13604.1 EGC31159.1 - 0.11 12.0 0.2 4.5 6.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_19 PF13245.1 EGC31159.1 - 0.11 12.2 0.2 12 5.6 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EGC31159.1 - 0.15 12.0 0.8 0.35 10.8 0.2 1.9 2 0 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGC31159.1 - 0.15 12.3 6.5 0.76 10.0 0.0 3.7 4 0 0 4 4 3 0 AAA domain Pkinase_Tyr PF07714.12 EGC31160.1 - 7.3e-55 185.8 0.0 1.4e-54 184.9 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC31160.1 - 4.3e-51 173.5 0.2 2.2e-49 167.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Ank_2 PF12796.2 EGC31160.1 - 6.1e-35 119.4 1.2 7.7e-12 45.3 0.3 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC31160.1 - 1.9e-31 106.2 0.2 1.4e-06 27.7 0.0 5.7 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EGC31160.1 - 1.9e-26 91.9 7.6 3.5e-08 33.7 0.0 6.6 2 1 5 7 7 7 6 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC31160.1 - 2.1e-21 75.4 3.1 6.9e-06 26.1 0.1 5.3 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC31160.1 - 2.6e-20 70.4 1.9 1.3e-05 24.9 0.0 6.5 7 0 0 7 7 6 4 Ankyrin repeat SAM_1 PF00536.25 EGC31160.1 - 1.3e-10 41.2 0.6 3.1e-10 40.0 0.4 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC31160.1 - 1.2e-07 31.4 0.3 3.2e-07 30.1 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF3013 PF11217.3 EGC31160.1 - 0.0099 15.6 0.5 0.034 13.8 0.4 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3013) AMNp_N PF10423.4 EGC31160.1 - 0.03 13.9 0.9 21 4.6 0.0 3.2 2 1 1 3 3 3 0 Bacterial AMP nucleoside phosphorylase N-terminus APH PF01636.18 EGC31160.1 - 0.054 13.2 0.1 0.29 10.8 0.1 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Dicty_CAR PF05462.6 EGC31161.1 - 5.7e-177 587.0 17.7 7.5e-177 586.6 12.2 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EGC31161.1 - 1.4e-09 37.4 16.7 1.4e-09 37.4 11.6 1.5 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) CbiQ PF02361.11 EGC31161.1 - 3.2 7.2 6.9 0.21 11.1 1.0 1.7 2 0 0 2 2 2 0 Cobalt transport protein DUF4229 PF14012.1 EGC31161.1 - 7.3 6.5 9.6 2.3 8.1 0.6 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4229) Git3 PF11710.3 EGC31161.1 - 7.7 6.0 22.7 0.051 13.1 7.5 2.3 1 1 1 2 2 2 0 G protein-coupled glucose receptor regulating Gpa2 EFP_N PF08207.7 EGC31162.1 - 3.8e-11 42.6 0.3 8.1e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Elong-fact-P_C PF09285.6 EGC31162.1 - 0.081 12.2 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 Elongation factor P, C-terminal DUF3737 PF12541.3 EGC31162.1 - 0.12 11.3 0.1 0.18 10.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3737) Neuroparsin PF07327.6 EGC31163.1 - 0.62 10.3 4.8 1.3 9.2 3.3 1.4 1 0 0 1 1 1 0 Neuroparsin P-II PF00543.17 EGC31164.1 - 0.029 14.8 0.4 7.3 7.1 0.1 2.4 2 0 0 2 2 2 0 Nitrogen regulatory protein P-II MGS PF02142.17 EGC31164.1 - 0.17 11.8 2.1 0.17 11.7 0.2 1.9 2 1 0 2 2 2 0 MGS-like domain Sex_peptide PF08138.6 EGC31164.1 - 0.17 11.7 0.1 1.6 8.6 0.0 2.3 2 0 0 2 2 2 0 Sex peptide (SP) family Response_reg PF00072.19 EGC31166.1 - 2.5e-27 95.1 0.1 5e-27 94.1 0.1 1.6 1 0 0 1 1 1 1 Response regulator receiver domain HATPase_c PF02518.21 EGC31166.1 - 4.5e-25 87.5 0.0 1.3e-24 86.0 0.0 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGC31166.1 - 5.9e-11 42.2 0.8 1.9e-10 40.5 0.0 2.4 2 1 1 3 3 3 1 His Kinase A (phospho-acceptor) domain PAS PF00989.19 EGC31166.1 - 6e-06 26.0 0.0 0.0023 17.6 0.0 3.5 3 0 0 3 3 3 1 PAS fold PAS_9 PF13426.1 EGC31166.1 - 0.0002 21.6 1.1 0.65 10.4 0.0 3.7 3 0 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EGC31166.1 - 0.027 14.5 0.0 2 8.4 0.0 2.3 2 0 0 2 2 2 0 PAS fold TetR_C_9 PF14514.1 EGC31166.1 - 0.11 12.3 0.0 0.58 9.9 0.0 2.1 2 0 0 2 2 2 0 Transcriptional regulator, TetR, C-terminal zf-DHHC PF01529.15 EGC31167.1 - 7.1e-34 116.7 22.8 7.1e-34 116.7 15.8 3.7 1 1 1 2 2 2 1 DHHC palmitoyltransferase Shisa PF13908.1 EGC31167.1 - 0.065 13.4 0.0 0.065 13.4 0.0 2.7 2 2 0 2 2 2 0 Wnt and FGF inhibitory regulator DUF2207 PF09972.4 EGC31167.1 - 0.48 8.9 12.0 0.047 12.2 0.4 2.9 1 1 1 3 3 3 0 Predicted membrane protein (DUF2207) Peptidase_C54 PF03416.14 EGC31168.1 - 6.2e-84 281.4 1.0 1e-83 280.7 0.7 1.3 1 0 0 1 1 1 1 Peptidase family C54 Rad60-SLD PF11976.3 EGC31169.1 - 1.6e-09 37.2 0.0 4.3e-09 35.9 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Hydantoinase_B PF02538.9 EGC31170.1 - 2.9e-191 636.2 0.6 3.8e-191 635.9 0.4 1.1 1 0 0 1 1 1 1 Hydantoinase B/oxoprolinase Hydantoinase_A PF01968.13 EGC31170.1 - 1.6e-87 293.3 0.0 2.8e-87 292.4 0.0 1.4 1 0 0 1 1 1 1 Hydantoinase/oxoprolinase Hydant_A_N PF05378.8 EGC31170.1 - 1.2e-52 178.0 1.0 3.8e-51 173.0 0.0 2.5 2 0 0 2 2 2 1 Hydantoinase/oxoprolinase N-terminal region Phage_Mu_Gp45 PF06890.7 EGC31170.1 - 0.013 14.9 0.0 0.031 13.7 0.0 1.6 1 0 0 1 1 1 0 Bacteriophage Mu Gp45 protein Proteasome_A_N PF10584.4 EGC31170.1 - 0.11 11.8 0.0 0.27 10.6 0.0 1.6 1 0 0 1 1 1 0 Proteasome subunit A N-terminal signature FNIP PF05725.7 EGC31171.1 - 1.9e-41 139.7 45.8 5.7e-11 42.1 1.0 8.8 3 2 5 9 9 9 7 FNIP Repeat DUF1769 PF08588.5 EGC31171.1 - 0.00038 20.3 9.1 7.3 6.6 0.0 6.0 5 3 0 5 5 5 4 Protein of unknown function (DUF1769) FtsJ PF01728.14 EGC31172.1 - 1.9e-52 177.8 0.1 3.8e-52 176.9 0.1 1.5 1 0 0 1 1 1 1 FtsJ-like methyltransferase Spb1_C PF07780.7 EGC31172.1 - 7.9e-52 175.8 65.5 7.9e-52 175.8 45.4 4.9 2 2 0 2 2 2 1 Spb1 C-terminal domain DUF3381 PF11861.3 EGC31172.1 - 1.2e-37 128.9 18.0 1.2e-37 128.9 12.5 6.3 3 2 4 7 7 7 1 Domain of unknown function (DUF3381) DUF3764 PF12594.3 EGC31172.1 - 0.0025 17.5 2.0 0.24 11.1 0.1 3.0 2 0 0 2 2 2 2 Protein of unknown function (DUF3764) DUF148 PF02520.12 EGC31172.1 - 0.0037 17.0 2.1 0.0037 17.0 1.5 3.4 3 1 0 3 3 3 1 Domain of unknown function DUF148 MFS_1 PF07690.11 EGC31173.1 - 5.3e-15 54.9 34.6 5.3e-15 54.9 24.0 2.0 1 1 0 2 2 2 1 Major Facilitator Superfamily DUF1228 PF06779.9 EGC31173.1 - 0.00037 20.4 0.5 0.00037 20.4 0.4 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1228) MFS_3 PF05977.8 EGC31173.1 - 0.015 13.4 6.1 0.01 13.9 1.6 2.2 1 1 1 2 2 2 0 Transmembrane secretion effector YtxH PF12732.2 EGC31173.1 - 2.7 8.4 3.6 0.98 9.8 0.3 1.9 2 0 0 2 2 2 0 YtxH-like protein SAP18 PF06487.7 EGC31174.1 - 1.3e-32 112.0 0.2 1.6e-32 111.8 0.1 1.0 1 0 0 1 1 1 1 Sin3 associated polypeptide p18 (SAP18) Adeno_E3_CR2 PF02439.10 EGC31176.1 - 0.009 15.5 0.3 0.018 14.5 0.2 1.5 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 PIRT PF15099.1 EGC31176.1 - 0.013 14.6 1.7 0.066 12.4 0.2 2.2 2 0 0 2 2 2 0 Phosphoinositide-interacting protein family TMEM154 PF15102.1 EGC31176.1 - 0.082 12.6 1.8 0.31 10.7 1.3 2.0 1 1 0 1 1 1 0 TMEM154 protein family Rieske PF00355.21 EGC31177.1 - 5.4e-17 61.1 0.2 1e-16 60.2 0.1 1.4 1 0 0 1 1 1 1 Rieske [2Fe-2S] domain UCR_TM PF02921.9 EGC31177.1 - 1.1e-13 51.1 0.0 1.8e-13 50.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquinol cytochrome reductase transmembrane region OTU PF02338.14 EGC31179.1 - 8.3e-13 48.9 0.2 8.3e-13 48.9 0.2 2.3 2 0 0 2 2 1 1 OTU-like cysteine protease PAT1 PF09770.4 EGC31179.1 - 0.053 11.7 62.2 0.066 11.4 43.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Gti1_Pac2 PF09729.4 EGC31179.1 - 0.056 13.3 3.9 0.087 12.6 2.7 1.3 1 0 0 1 1 1 0 Gti1/Pac2 family XRN_N PF03159.13 EGC31179.1 - 0.062 12.6 4.5 0.098 12.0 3.1 1.3 1 0 0 1 1 1 0 XRN 5'-3' exonuclease N-terminus DUF4175 PF13779.1 EGC31179.1 - 0.11 10.2 34.5 0.13 9.8 23.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) TFIIA PF03153.8 EGC31179.1 - 0.18 11.6 35.4 0.2 11.4 24.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 EGC31179.1 - 0.19 11.0 28.5 0.24 10.6 19.8 1.2 1 0 0 1 1 1 0 SprA-related family Plasmodium_Vir PF05795.6 EGC31179.1 - 0.19 10.8 10.1 0.1 11.7 1.9 2.2 2 0 0 2 2 2 0 Plasmodium vivax Vir protein Trypan_PARP PF05887.6 EGC31179.1 - 0.62 9.8 17.1 0.53 10.0 7.1 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) CheR_N PF03705.10 EGC31179.1 - 0.68 9.3 3.1 3.6 7.0 0.3 2.3 2 0 0 2 2 2 0 CheR methyltransferase, all-alpha domain DUF853 PF05872.7 EGC31179.1 - 0.86 7.8 11.6 1.2 7.4 8.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Band_3_cyto PF07565.8 EGC31179.1 - 0.93 8.9 11.6 4.5 6.7 8.4 1.8 2 0 0 2 2 2 0 Band 3 cytoplasmic domain YjgP_YjgQ PF03739.9 EGC31179.1 - 1.5 7.5 3.3 1.9 7.1 2.3 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family RR_TM4-6 PF06459.7 EGC31179.1 - 4.5 7.0 14.9 6.2 6.6 10.3 1.2 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 GATA PF00320.22 EGC31180.1 - 6e-07 28.7 1.7 1.1e-06 27.8 1.2 1.4 1 0 0 1 1 1 1 GATA zinc finger TF_Zn_Ribbon PF08271.7 EGC31180.1 - 0.025 13.9 0.7 0.062 12.6 0.5 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding zf-RanBP PF00641.13 EGC31180.1 - 0.11 11.5 2.9 2.7 7.2 0.1 2.5 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others AT_hook PF02178.14 EGC31180.1 - 0.54 10.1 5.9 1.5 8.7 4.1 1.8 1 0 0 1 1 1 0 AT hook motif Thioredoxin PF00085.15 EGC31181.1 - 2.8e-05 23.7 0.1 5.2e-05 22.8 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Clathrin_propel PF01394.15 EGC31181.1 - 0.035 14.4 3.6 0.13 12.5 2.5 2.0 1 0 0 1 1 1 0 Clathrin propeller repeat Thioredoxin_3 PF13192.1 EGC31181.1 - 0.043 13.6 0.0 0.085 12.6 0.0 1.5 1 0 0 1 1 1 0 Thioredoxin domain Thioredoxin_7 PF13899.1 EGC31181.1 - 0.075 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Thioredoxin-like Thioredoxin PF00085.15 EGC31182.1 - 2.8e-13 49.4 0.0 4.4e-13 48.8 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_6 PF13848.1 EGC31182.1 - 0.0077 16.0 2.9 0.077 12.7 0.1 2.1 2 0 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC31182.1 - 0.013 15.6 2.7 0.027 14.5 0.0 2.5 2 1 0 2 2 2 0 Thioredoxin-like Thioredoxin PF00085.15 EGC31183.1 - 2.5e-23 81.7 0.0 2.7e-23 81.6 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGC31183.1 - 1.2e-11 44.7 0.0 4.7e-11 42.8 0.0 1.7 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC31183.1 - 1.6e-08 34.5 0.0 5.3e-07 29.6 0.0 2.1 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_7 PF13899.1 EGC31183.1 - 1.7e-08 34.3 0.0 2.2e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_3 PF13192.1 EGC31183.1 - 3e-05 23.7 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_9 PF14595.1 EGC31183.1 - 3.6e-05 23.3 0.0 3.6e-05 23.3 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin AhpC-TSA PF00578.16 EGC31183.1 - 0.00021 20.9 0.0 0.00025 20.7 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family DUF836 PF05768.9 EGC31183.1 - 0.00036 20.7 0.0 0.0006 20.0 0.0 1.4 1 1 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Thioredoxin_6 PF13848.1 EGC31183.1 - 0.0021 17.8 0.0 0.0022 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EGC31183.1 - 0.0065 16.0 0.0 0.0081 15.7 0.0 1.3 1 0 0 1 1 1 1 Redoxin TrbC_Ftype PF09673.5 EGC31183.1 - 0.024 14.2 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Type-F conjugative transfer system pilin assembly protein Glutaredoxin PF00462.19 EGC31183.1 - 0.056 13.4 0.1 0.1 12.6 0.0 1.5 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_4 PF13462.1 EGC31183.1 - 0.085 12.8 0.0 0.17 11.9 0.0 1.6 1 1 1 2 2 2 0 Thioredoxin KaiB PF07689.7 EGC31183.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 KaiB domain zf-C3HC4_2 PF13923.1 EGC31184.1 - 4.1e-13 49.1 9.1 6.3e-13 48.5 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC31184.1 - 1.2e-12 47.4 9.3 1.7e-12 46.9 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC31184.1 - 3.9e-12 45.6 8.2 6.6e-12 44.8 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31184.1 - 6.3e-11 41.8 8.1 9.6e-11 41.2 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC31184.1 - 8.7e-11 41.3 5.6 1.2e-10 40.8 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC31184.1 - 1.7e-08 34.1 9.1 2.7e-08 33.5 6.3 1.3 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC31184.1 - 1.7e-07 30.8 4.2 2e-07 30.5 0.6 2.4 1 1 1 2 2 2 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGC31184.1 - 7.2e-06 26.0 5.9 1.1e-05 25.3 4.1 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Nse PF11789.3 EGC31184.1 - 6.3e-05 22.4 4.2 0.0001 21.7 2.9 1.3 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-Apc11 PF12861.2 EGC31184.1 - 0.0002 21.1 3.7 0.00033 20.4 2.6 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGC31184.1 - 0.00071 19.3 3.5 0.0012 18.5 2.4 1.3 1 0 0 1 1 1 1 zf-RING of BARD1-type protein Rtf2 PF04641.7 EGC31184.1 - 0.0044 16.2 1.0 0.0044 16.2 0.7 1.9 1 1 1 2 2 2 1 Rtf2 RING-finger Baculo_IE-1 PF05290.6 EGC31184.1 - 0.0058 16.3 3.6 0.0084 15.8 2.5 1.2 1 0 0 1 1 1 1 Baculovirus immediate-early protein (IE-0) Prok-RING_4 PF14447.1 EGC31184.1 - 0.006 16.1 5.2 0.013 15.0 3.6 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 Dicty_REP PF05086.7 EGC31184.1 - 0.011 13.4 3.7 0.015 13.1 2.6 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_4 PF14570.1 EGC31184.1 - 0.013 15.0 6.8 0.028 14.0 4.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain U-box PF04564.10 EGC31184.1 - 0.022 14.7 0.2 0.069 13.1 0.0 1.8 2 0 0 2 2 2 0 U-box domain SOG2 PF10428.4 EGC31184.1 - 0.023 13.3 9.2 0.036 12.7 6.4 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein zf-UDP PF14569.1 EGC31184.1 - 0.051 13.3 2.7 0.13 12.0 1.8 1.7 1 1 0 1 1 1 0 Zinc-binding RING-finger zf-MIZ PF02891.15 EGC31184.1 - 0.083 12.4 9.4 0.13 11.8 6.5 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger RINGv PF12906.2 EGC31184.1 - 0.13 12.3 7.2 0.36 10.9 5.0 1.7 1 1 0 1 1 1 0 RING-variant domain zf-P11 PF03854.9 EGC31184.1 - 0.15 11.5 5.6 0.27 10.7 3.9 1.4 1 0 0 1 1 1 0 P-11 zinc finger Pex14_N PF04695.8 EGC31184.1 - 0.21 11.6 13.5 0.29 11.1 3.1 2.9 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-CHY PF05495.7 EGC31184.1 - 0.26 11.4 3.8 0.44 10.7 2.6 1.3 1 0 0 1 1 1 0 CHY zinc finger DUF3439 PF11921.3 EGC31184.1 - 0.59 9.8 10.3 1 9.0 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Baculo_RING PF05883.6 EGC31184.1 - 1.2 8.9 4.6 2.4 7.9 3.2 1.5 1 1 0 1 1 1 0 Baculovirus U-box/Ring-like domain V-SNARE_C PF12352.3 EGC31186.1 - 1.2e-07 31.7 2.6 1.2e-07 31.7 1.8 2.0 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus TUSC2 PF15000.1 EGC31186.1 - 0.0015 18.6 0.3 0.0032 17.4 0.2 1.6 1 0 0 1 1 1 1 Tumour suppressor candidate 2 Sec20 PF03908.8 EGC31186.1 - 0.0093 15.6 2.5 0.0093 15.6 1.7 2.2 2 1 1 3 3 3 1 Sec20 SNARE PF05739.14 EGC31186.1 - 0.018 14.7 3.2 0.018 14.7 2.2 3.6 3 1 0 3 3 3 0 SNARE domain MCPsignal PF00015.16 EGC31186.1 - 0.034 13.7 0.9 0.034 13.7 0.7 1.6 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain B2 PF11473.3 EGC31186.1 - 0.12 11.9 1.2 0.34 10.5 0.3 2.1 2 0 0 2 2 2 0 RNA binding protein B2 Syntaxin-6_N PF09177.6 EGC31186.1 - 0.42 11.0 6.9 7 7.1 0.1 2.5 2 0 0 2 2 2 0 Syntaxin 6, N-terminal Allexi_40kDa PF05549.6 EGC31186.1 - 0.7 9.1 12.3 1.9 7.7 3.1 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein ALMT PF11744.3 EGC31186.1 - 1.4 7.4 5.4 2.1 6.8 3.7 1.4 1 1 0 1 1 1 0 Aluminium activated malate transporter Laminin_II PF06009.7 EGC31186.1 - 4.2 7.1 16.0 12 5.7 0.8 3.3 1 1 2 3 3 3 0 Laminin Domain II DASH_Dad1 PF08649.5 EGC31186.1 - 5 6.8 9.6 0.72 9.6 1.6 2.9 3 0 0 3 3 3 0 DASH complex subunit Dad1 DASH_Duo1 PF08651.5 EGC31186.1 - 8.5 6.0 12.9 1 8.9 0.1 3.9 2 2 2 4 4 4 0 DASH complex subunit Duo1 NPV_P10 PF05531.7 EGC31186.1 - 9.1 6.6 10.6 3.1 8.0 0.7 3.3 3 2 0 3 3 3 0 Nucleopolyhedrovirus P10 protein Cytochrom_C PF00034.16 EGC31188.1 - 1.4e-11 45.1 0.1 2.2e-11 44.4 0.1 1.3 1 1 0 1 1 1 1 Cytochrome c Cytochrome_CBB3 PF13442.1 EGC31188.1 - 7.7e-08 32.3 1.9 2.5e-07 30.7 1.3 1.7 1 1 0 1 1 1 1 Cytochrome C oxidase, cbb3-type, subunit III Cytochrom_C550 PF14495.1 EGC31188.1 - 0.0034 16.8 0.2 0.0094 15.4 0.0 1.8 2 1 0 2 2 2 1 Cytochrome c-550 domain Abhydrolase_5 PF12695.2 EGC31189.1 - 2.8e-08 33.6 0.0 5.8e-08 32.6 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC31189.1 - 8.8e-06 25.0 0.0 1.8e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGC31189.1 - 0.0049 16.4 0.0 0.01 15.3 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC31189.1 - 0.0081 16.0 0.0 0.025 14.4 0.0 1.5 1 1 1 2 2 2 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGC31189.1 - 0.038 13.5 0.0 0.076 12.5 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein DUF3439 PF11921.3 EGC31192.1 - 7.7 6.2 9.7 6.2 6.5 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC31193.1 - 3.6 7.3 10.4 6.8 6.4 7.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Metallophos PF00149.23 EGC31194.1 - 8.1e-15 54.7 2.8 8.1e-15 54.7 1.9 1.7 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase SHOCT PF09851.4 EGC31194.1 - 0.033 13.6 0.0 0.098 12.1 0.0 1.8 1 0 0 1 1 1 0 Short C-terminal domain GP41 PF00517.12 EGC31194.1 - 0.043 13.3 0.3 0.087 12.3 0.2 1.5 1 0 0 1 1 1 0 Retroviral envelope protein Acyltransferase PF01553.16 EGC31195.1 - 4.1e-06 26.2 0.0 4.5e-05 22.9 0.0 2.5 2 1 0 2 2 2 1 Acyltransferase Z1 PF10593.4 EGC31195.1 - 0.079 12.1 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Z1 domain Adeno_E3_CR2 PF02439.10 EGC31195.1 - 0.64 9.6 4.2 1.2 8.7 2.9 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 ADH_zinc_N PF00107.21 EGC31196.1 - 3.6e-12 45.9 0.0 6.7e-12 45.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC31196.1 - 7.4e-08 32.1 0.0 1.8e-07 30.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC31196.1 - 9.5e-06 26.5 0.0 2.4e-05 25.2 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PFO_beta_C PF12367.3 EGC31196.1 - 0.1 12.5 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal Mem_trans PF03547.13 EGC31197.1 - 0.17 10.1 5.0 0.3 9.3 1.0 2.1 2 0 0 2 2 2 0 Membrane transport protein DUF3137 PF11335.3 EGC31198.1 - 0.23 11.1 3.8 0.44 10.2 0.4 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3137) LAGLIDADG_3 PF14528.1 EGC31199.1 - 0.23 11.7 2.1 0.24 11.6 0.7 1.6 1 1 0 1 1 1 0 LAGLIDADG-like domain DUF912 PF06024.7 EGC31199.1 - 4.9 7.2 9.6 11 6.0 6.6 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Bax1-I PF01027.15 EGC31200.1 - 1.5e-06 27.9 10.5 8.1e-06 25.5 7.3 1.9 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Bax1-I PF01027.15 EGC31201.1 - 1.5e-19 70.4 8.8 2.1e-19 69.9 6.1 1.2 1 1 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF2177 PF09945.4 EGC31201.1 - 0.032 14.2 0.5 0.092 12.7 0.2 1.8 1 1 1 2 2 2 0 Predicted membrane protein (DUF2177) DUF373 PF04123.8 EGC31201.1 - 0.61 9.0 6.1 3.7 6.4 0.5 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF373) ERM PF00769.14 EGC31202.1 - 0.00066 19.2 5.6 0.00075 19.1 3.9 1.0 1 0 0 1 1 1 1 Ezrin/radixin/moesin family Kinesin-relat_1 PF12711.2 EGC31202.1 - 0.00067 20.0 5.1 0.0017 18.7 3.4 1.8 1 1 0 1 1 1 1 Kinesin motor TelA PF05816.6 EGC31202.1 - 0.0012 17.5 3.9 0.0014 17.3 2.7 1.0 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) Spc7 PF08317.6 EGC31202.1 - 0.002 16.8 5.3 0.0021 16.7 3.7 1.0 1 0 0 1 1 1 1 Spc7 kinetochore protein bZIP_1 PF00170.16 EGC31202.1 - 0.0021 17.9 9.9 0.029 14.3 1.2 2.2 1 1 1 2 2 2 2 bZIP transcription factor CorA PF01544.13 EGC31202.1 - 0.0027 16.7 1.2 0.0031 16.6 0.8 1.0 1 0 0 1 1 1 1 CorA-like Mg2+ transporter protein DUF904 PF06005.7 EGC31202.1 - 0.0074 16.5 11.4 0.056 13.7 1.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EGC31202.1 - 0.011 15.5 11.1 0.22 11.3 0.8 2.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding BicD PF09730.4 EGC31202.1 - 0.015 13.7 5.1 0.017 13.4 3.5 1.0 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D DUF603 PF04645.7 EGC31202.1 - 0.017 15.0 4.1 0.02 14.8 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Cep57_MT_bd PF06657.8 EGC31202.1 - 0.026 14.4 6.7 0.056 13.3 1.8 2.3 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Atg14 PF10186.4 EGC31202.1 - 0.029 13.3 6.4 0.033 13.1 4.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 TSC22 PF01166.13 EGC31202.1 - 0.032 14.1 8.7 0.081 12.9 0.8 2.5 1 1 1 2 2 2 0 TSC-22/dip/bun family MAD PF05557.8 EGC31202.1 - 0.034 12.2 5.7 0.036 12.1 3.9 1.1 1 0 0 1 1 1 0 Mitotic checkpoint protein DASH_Dad2 PF08654.5 EGC31202.1 - 0.047 13.7 4.9 1.8 8.5 0.5 2.1 1 1 1 2 2 2 0 DASH complex subunit Dad2 DUF848 PF05852.6 EGC31202.1 - 0.047 13.5 7.5 1 9.2 5.2 1.9 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Phage_GP20 PF06810.6 EGC31202.1 - 0.047 13.1 8.9 0.052 12.9 6.2 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DivIC PF04977.10 EGC31202.1 - 0.048 13.1 10.6 0.51 9.8 2.1 2.2 1 1 1 2 2 2 0 Septum formation initiator DUF1319 PF07028.6 EGC31202.1 - 0.054 13.6 3.7 0.072 13.2 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1319) FimP PF09766.4 EGC31202.1 - 0.056 12.5 5.9 0.39 9.7 1.1 2.0 2 0 0 2 2 2 0 Fms-interacting protein HALZ PF02183.13 EGC31202.1 - 0.061 13.0 7.5 2.8 7.7 4.7 2.5 1 1 0 1 1 1 0 Homeobox associated leucine zipper Prefoldin PF02996.12 EGC31202.1 - 0.071 12.7 0.8 0.071 12.7 0.6 2.1 1 1 1 2 2 2 0 Prefoldin subunit ACCA PF03255.9 EGC31202.1 - 0.074 12.5 2.2 0.07 12.6 0.9 1.4 1 1 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit KAR9 PF08580.5 EGC31202.1 - 0.08 11.2 2.9 0.095 10.9 2.0 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 PspA_IM30 PF04012.7 EGC31202.1 - 0.1 11.9 4.2 0.47 9.7 0.4 1.9 1 1 1 2 2 2 0 PspA/IM30 family Microtub_assoc PF07989.6 EGC31202.1 - 0.11 12.3 11.1 0.075 12.8 1.6 2.5 1 1 2 3 3 2 0 Microtubule associated Lectin_N PF03954.9 EGC31202.1 - 0.11 11.8 3.1 1.2 8.4 0.1 2.1 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain TPR_MLP1_2 PF07926.7 EGC31202.1 - 0.12 12.1 6.7 0.19 11.5 2.9 2.1 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein FlaC_arch PF05377.6 EGC31202.1 - 0.12 12.3 7.5 0.13 12.1 1.0 2.2 1 1 1 2 2 2 0 Flagella accessory protein C (FlaC) HalX PF08663.5 EGC31202.1 - 0.14 12.2 0.7 0.53 10.3 0.0 2.1 1 1 1 2 2 2 0 HalX domain DUF4200 PF13863.1 EGC31202.1 - 0.14 12.0 11.1 0.64 9.9 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) BRE1 PF08647.6 EGC31202.1 - 0.15 12.0 9.1 0.29 11.1 6.3 1.5 1 1 0 1 1 1 0 BRE1 E3 ubiquitin ligase DUF972 PF06156.8 EGC31202.1 - 0.22 11.8 5.6 0.35 11.2 3.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF972) DUF4618 PF15397.1 EGC31202.1 - 0.22 10.7 7.6 0.54 9.5 0.7 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) Herpes_UL6 PF01763.11 EGC31202.1 - 0.25 9.4 4.3 0.26 9.4 3.0 1.0 1 0 0 1 1 1 0 Herpesvirus UL6 like Laminin_II PF06009.7 EGC31202.1 - 0.33 10.7 3.3 0.39 10.4 2.3 1.1 1 0 0 1 1 1 0 Laminin Domain II TBPIP PF07106.8 EGC31202.1 - 0.39 10.2 9.1 0.47 9.9 6.3 1.1 1 0 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Mnd1 PF03962.10 EGC31202.1 - 0.39 10.3 6.2 1.1 8.8 4.3 1.7 1 1 0 1 1 1 0 Mnd1 family SYCE1 PF15233.1 EGC31202.1 - 0.45 10.4 9.6 0.5 10.2 1.8 2.2 1 1 1 2 2 2 0 Synaptonemal complex central element protein 1 Wbp11 PF09429.5 EGC31202.1 - 0.5 10.3 8.3 1.5 8.8 1.0 2.3 1 1 1 2 2 2 0 WW domain binding protein 11 DUF2205 PF10224.4 EGC31202.1 - 0.53 9.8 8.1 0.12 12.0 1.3 2.1 1 1 1 2 2 2 0 Predicted coiled-coil protein (DUF2205) DUF3450 PF11932.3 EGC31202.1 - 0.55 9.4 3.5 1 8.5 2.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3450) WEMBL PF05701.6 EGC31202.1 - 0.6 8.4 7.1 0.81 8.0 4.9 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Fmp27_WPPW PF10359.4 EGC31202.1 - 0.64 8.3 5.9 0.72 8.2 4.1 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain Spectrin PF00435.16 EGC31202.1 - 0.72 10.1 4.7 0.79 10.0 3.0 1.3 1 1 0 1 1 1 0 Spectrin repeat K-box PF01486.12 EGC31202.1 - 0.74 9.6 8.0 8.8 6.1 5.5 2.1 1 1 0 1 1 1 0 K-box region Vps51 PF08700.6 EGC31202.1 - 0.79 9.6 4.6 5 7.0 0.1 2.6 2 2 0 2 2 2 0 Vps51/Vps67 CCDC155 PF14662.1 EGC31202.1 - 0.81 9.2 9.4 2.2 7.8 5.9 1.8 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 Seryl_tRNA_N PF02403.17 EGC31202.1 - 0.84 9.6 9.3 1.2 9.1 1.3 2.0 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain Ax_dynein_light PF10211.4 EGC31202.1 - 0.87 9.3 9.4 1.7 8.4 1.2 2.0 1 1 1 2 2 2 0 Axonemal dynein light chain Spc24 PF08286.6 EGC31202.1 - 0.89 9.2 9.4 81 2.9 6.5 2.1 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Fib_alpha PF08702.5 EGC31202.1 - 0.94 9.5 7.0 0.93 9.6 0.7 2.1 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family APG6 PF04111.7 EGC31202.1 - 0.98 8.3 7.1 1.3 8.0 4.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Kinesin-related PF06548.6 EGC31202.1 - 1.1 7.6 8.4 0.62 8.5 2.0 1.8 1 1 0 1 1 1 0 Kinesin-related Transposase_22 PF02994.9 EGC31202.1 - 1.4 7.3 6.5 1.7 7.0 4.5 1.2 1 0 0 1 1 1 0 L1 transposable element DUF1664 PF07889.7 EGC31202.1 - 1.4 8.7 5.0 2.1 8.1 3.5 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) ATG16 PF08614.6 EGC31202.1 - 1.4 8.6 11.3 4 7.2 5.7 2.0 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Cep57_CLD_2 PF14197.1 EGC31202.1 - 1.4 8.8 7.1 4.7 7.2 0.6 2.4 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 Rbsn PF11464.3 EGC31202.1 - 1.5 8.4 4.7 35 4.0 0.1 3.5 4 0 0 4 4 4 0 Rabenosyn Rab binding domain GrpE PF01025.14 EGC31202.1 - 1.5 8.3 4.9 2.3 7.7 3.3 1.4 1 1 0 1 1 1 0 GrpE ADIP PF11559.3 EGC31202.1 - 1.6 8.6 8.7 1.2 8.9 4.8 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding YlqD PF11068.3 EGC31202.1 - 1.6 8.7 8.3 2.1 8.4 5.8 1.0 1 0 0 1 1 1 0 YlqD protein TMCO5 PF14992.1 EGC31202.1 - 1.8 7.6 8.7 2.1 7.4 6.0 1.1 1 0 0 1 1 1 0 TMCO5 family DUF3573 PF12097.3 EGC31202.1 - 1.9 7.0 5.6 4.7 5.7 3.9 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3573) USP8_interact PF08941.5 EGC31202.1 - 2.4 7.4 5.3 2 7.7 0.4 2.0 1 1 1 2 2 2 0 USP8 interacting Uso1_p115_C PF04871.8 EGC31202.1 - 2.5 8.0 7.8 3.3 7.6 5.4 1.3 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region Bap31 PF05529.7 EGC31202.1 - 2.6 7.4 6.1 5.3 6.4 4.2 1.6 1 1 0 1 1 1 0 B-cell receptor-associated protein 31-like DUF641 PF04859.7 EGC31202.1 - 3 7.5 5.6 8 6.2 3.9 1.7 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Macoilin PF09726.4 EGC31202.1 - 3.1 5.9 7.7 3.6 5.7 5.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Striatin PF08232.7 EGC31202.1 - 3.5 7.9 8.1 25 5.1 5.6 1.9 1 1 0 1 1 1 0 Striatin family Prefoldin_2 PF01920.15 EGC31202.1 - 3.8 7.3 11.5 1 9.1 2.2 2.1 1 1 1 2 2 2 0 Prefoldin subunit DUF342 PF03961.8 EGC31202.1 - 5.2 5.3 6.9 6 5.1 4.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3166 PF11365.3 EGC31202.1 - 5.9 7.4 6.6 9.8 6.7 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3166) zf-C3HC4_3 PF13920.1 EGC31203.1 - 4.6e-09 35.8 7.9 9.3e-09 34.8 5.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31203.1 - 0.00017 21.4 11.9 0.00079 19.4 8.7 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EGC31203.1 - 0.0019 18.1 21.9 0.0035 17.3 15.2 1.4 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.20 EGC31203.1 - 0.0038 16.8 13.5 0.0081 15.7 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SPRY PF00622.23 EGC31203.1 - 0.0093 16.0 0.0 0.043 13.9 0.0 2.1 1 1 0 1 1 1 1 SPRY domain zf-RING_2 PF13639.1 EGC31203.1 - 0.19 11.5 12.3 0.45 10.3 8.6 1.7 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EGC31203.1 - 0.7 9.6 11.7 1.4 8.6 8.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Glyco_hydro_9 PF00759.14 EGC31204.1 - 2.4e-119 399.1 22.3 2.9e-119 398.8 15.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Ribosomal_S19 PF00203.16 EGC31205.1 - 6.4e-26 89.7 0.2 8.9e-26 89.3 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S19 CBM49 PF09478.5 EGC31206.1 - 5.3e-15 55.2 0.2 6.9e-15 54.9 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 FOLN PF09289.5 EGC31206.1 - 0.0053 16.5 1.0 0.0053 16.5 0.7 1.9 2 0 0 2 2 2 1 Follistatin/Osteonectin-like EGF domain CBM_2 PF00553.14 EGC31206.1 - 0.043 13.8 0.0 0.057 13.4 0.0 1.2 1 0 0 1 1 1 0 Cellulose binding domain FH2 PF02181.18 EGC31207.1 - 1e-92 310.9 6.2 1e-92 310.9 4.3 3.3 4 0 0 4 4 4 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGC31207.1 - 1.7e-28 99.2 1.0 1.7e-28 99.2 0.7 2.6 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGC31207.1 - 3.4e-25 88.6 4.6 3.4e-25 88.6 3.2 2.4 3 0 0 3 3 3 1 Diaphanous FH3 Domain Pex14_N PF04695.8 EGC31210.1 - 0.68 9.9 0.0 0.68 9.9 0.0 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region PEPcase_2 PF14010.1 EGC31212.1 - 0.0099 14.2 3.6 0.014 13.7 2.5 1.3 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase HD_3 PF13023.1 EGC31212.1 - 0.0099 15.6 1.6 0.016 14.9 1.1 1.4 1 0 0 1 1 1 1 HD domain RasGAP_C PF03836.10 EGC31212.1 - 1.6 8.3 23.7 51 3.5 16.4 2.2 1 1 0 1 1 1 0 RasGAP C-terminus Mur_ligase_M PF08245.7 EGC31213.1 - 0.089 12.8 0.3 0.15 12.0 0.1 1.4 2 0 0 2 2 2 0 Mur ligase middle domain Actin PF00022.14 EGC31214.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC31214.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) GPCR_chapero_1 PF11904.3 EGC31215.1 - 1.6 7.7 13.0 2 7.4 9.0 1.1 1 0 0 1 1 1 0 GPCR-chaperone PIP5K PF01504.13 EGC31217.1 - 4.1e-58 196.4 0.1 4.1e-58 196.4 0.1 2.8 3 0 0 3 3 3 1 Phosphatidylinositol-4-phosphate 5-Kinase Cpn60_TCP1 PF00118.19 EGC31217.1 - 1.5e-22 79.8 0.9 8.9e-22 77.3 0.6 2.1 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family Arf PF00025.16 EGC31218.1 - 4.4e-70 234.4 0.2 5.3e-70 234.1 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC31218.1 - 3.8e-14 52.3 0.0 4.9e-14 52.0 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC31218.1 - 2e-13 49.9 0.0 2.5e-13 49.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC31218.1 - 4.2e-10 38.8 3.0 1.8e-07 30.1 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit Miro PF08477.8 EGC31218.1 - 8.7e-08 32.6 0.0 1.3e-07 32.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC31218.1 - 2.3e-07 30.1 0.0 2.8e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC31218.1 - 0.00041 20.3 0.0 0.00056 19.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ArgK PF03308.11 EGC31218.1 - 0.028 13.2 0.1 0.1 11.3 0.0 1.8 2 1 1 3 3 3 0 ArgK protein Me-amine-dh_H PF06433.6 EGC31218.1 - 0.11 11.1 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Methylamine dehydrogenase heavy chain (MADH) Ras PF00071.17 EGC31219.1 - 5.2e-65 217.7 0.4 6.1e-65 217.5 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31219.1 - 7.7e-21 74.7 0.0 1.1e-20 74.2 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC31219.1 - 7e-16 57.9 0.1 8.5e-16 57.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC31219.1 - 3.9e-08 32.7 0.1 4.7e-08 32.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC31219.1 - 1.1e-05 24.9 0.2 2.3e-05 23.9 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC31219.1 - 0.00011 22.1 0.1 0.00025 20.9 0.0 1.5 1 1 1 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC31219.1 - 0.00091 18.4 0.1 0.0012 18.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC31219.1 - 0.0018 17.0 1.3 0.081 11.6 0.0 2.7 1 1 1 2 2 2 1 G-protein alpha subunit AAA_22 PF13401.1 EGC31219.1 - 0.0024 18.0 0.0 0.004 17.2 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA PF00004.24 EGC31219.1 - 0.005 17.0 0.0 0.25 11.5 0.0 2.2 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGC31219.1 - 0.019 14.1 0.0 0.06 12.5 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC31219.1 - 0.03 13.8 0.0 0.11 12.0 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC31219.1 - 0.036 14.0 0.1 0.054 13.4 0.1 1.5 1 1 0 1 1 1 0 AAA ATPase domain cobW PF02492.14 EGC31219.1 - 0.053 12.9 0.5 2.3 7.6 0.1 2.1 1 1 1 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGC31219.1 - 0.078 12.7 0.0 0.086 12.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGC31219.1 - 0.087 12.3 0.2 0.37 10.2 0.1 2.2 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation BTV_NS2 PF04514.7 EGC31220.1 - 0.00022 20.2 15.2 0.00029 19.8 10.5 1.2 1 0 0 1 1 1 1 Bluetongue virus non-structural protein NS2 SR-25 PF10500.4 EGC31220.1 - 0.23 10.8 16.9 0.31 10.4 11.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein BAF1_ABF1 PF04684.8 EGC31220.1 - 0.37 9.5 16.0 0.58 8.9 11.1 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor CENP-B_dimeris PF09026.5 EGC31220.1 - 0.53 10.5 8.1 0.11 12.6 2.9 1.9 2 0 0 2 2 2 0 Centromere protein B dimerisation domain Senescence_reg PF04520.8 EGC31220.1 - 0.68 10.4 12.3 1 9.8 8.5 1.3 1 0 0 1 1 1 0 Senescence regulator NOA36 PF06524.7 EGC31220.1 - 1.2 8.3 10.6 1.7 7.8 7.4 1.2 1 0 0 1 1 1 0 NOA36 protein LMBR1 PF04791.11 EGC31220.1 - 3.1 6.2 5.1 3 6.3 3.5 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DivIC PF04977.10 EGC31220.1 - 5 6.6 19.8 18 4.9 13.7 2.0 1 0 0 1 1 1 0 Septum formation initiator Cwf_Cwc_15 PF04889.7 EGC31220.1 - 8.1 6.0 32.0 13 5.4 22.2 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein SAC3_GANP PF03399.11 EGC31221.1 - 2.4e-57 193.8 2.6 2.4e-57 193.8 1.8 2.4 2 1 1 3 3 3 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family EI24 PF07264.6 EGC31222.1 - 0.077 12.4 0.0 0.093 12.1 0.0 1.1 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Spectrin PF00435.16 EGC31224.1 - 0.059 13.6 5.2 0.062 13.5 3.6 1.1 1 0 0 1 1 1 0 Spectrin repeat FlxA PF14282.1 EGC31224.1 - 0.14 12.0 16.1 0.18 11.7 11.1 1.1 1 0 0 1 1 1 0 FlxA-like protein DUF3373 PF11853.3 EGC31224.1 - 0.21 10.1 4.2 0.21 10.0 2.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) Katanin_con80 PF13925.1 EGC31224.1 - 0.24 11.1 2.8 0.28 10.9 2.0 1.0 1 0 0 1 1 1 0 con80 domain of Katanin DUF4407 PF14362.1 EGC31224.1 - 1.1 8.0 4.5 1.2 8.0 3.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3573 PF12097.3 EGC31224.1 - 3.7 6.0 5.8 3.5 6.1 4.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) FNIP PF05725.7 EGC31226.1 - 4.6e-58 192.9 98.4 2.9e-12 46.3 0.5 15.8 9 4 7 16 16 16 12 FNIP Repeat VD10_N PF08476.5 EGC31226.1 - 0.001 18.4 0.3 0.0086 15.5 0.0 2.5 1 1 1 2 2 2 1 Viral D10 N-terminal DUF1685 PF07939.6 EGC31226.1 - 0.06 13.0 2.2 1.7 8.3 0.0 3.3 3 1 1 4 4 4 0 Protein of unknown function (DUF1685) DUF3439 PF11921.3 EGC31226.1 - 0.56 9.9 9.5 1.3 8.7 6.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPPII_N PF12583.3 EGC31226.1 - 0.62 10.1 5.8 1.3 9.1 4.0 1.4 1 0 0 1 1 1 0 Tripeptidyl peptidase II N terminal SSP160 PF06933.6 EGC31226.1 - 3.5 5.4 16.7 4.9 5.0 11.6 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_11 PF13414.1 EGC31227.1 - 5.9e-49 163.5 47.3 4.1e-10 39.1 0.2 12.0 8 2 4 12 12 12 11 TPR repeat TPR_2 PF07719.12 EGC31227.1 - 4.1e-47 154.3 31.3 6.9e-06 25.5 0.1 17.0 18 0 0 18 18 17 11 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31227.1 - 1.8e-43 146.7 11.4 5.7e-09 36.1 0.0 11.5 10 2 1 12 12 12 9 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31227.1 - 8.7e-42 140.9 0.2 6e-07 29.9 0.0 11.3 4 3 7 12 12 12 7 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31227.1 - 1.1e-40 134.3 0.0 0.0014 19.1 0.0 12.9 6 4 6 13 13 12 9 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31227.1 - 1.1e-39 134.2 32.9 2.7e-07 30.4 0.0 11.7 4 3 9 13 13 13 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGC31227.1 - 7.3e-35 117.1 46.8 2.8e-07 29.8 0.1 16.6 17 0 0 17 17 17 7 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31227.1 - 3.9e-34 113.8 37.6 9.7e-06 25.0 0.1 16.1 16 1 1 17 17 17 8 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31227.1 - 4.5e-33 111.4 12.0 0.00072 19.8 0.1 13.3 14 0 0 14 14 13 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31227.1 - 5.2e-32 107.3 33.8 0.00038 20.4 0.0 16.3 18 0 0 18 18 18 9 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31227.1 - 9.7e-26 87.4 14.1 0.0069 16.1 0.0 14.2 15 0 0 15 15 15 5 Tetratricopeptide repeat Apc3 PF12895.2 EGC31227.1 - 2e-15 56.6 33.3 0.0023 18.0 0.4 8.5 6 2 4 10 10 8 6 Anaphase-promoting complex, cyclosome, subunit 3 TPR_10 PF13374.1 EGC31227.1 - 1.6e-09 37.3 23.2 1.3 9.1 0.1 12.2 14 0 0 14 14 14 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31227.1 - 3.8e-09 36.2 0.0 0.33 10.8 0.0 6.3 8 0 0 8 8 8 2 Tetratricopeptide repeat NARP1 PF12569.3 EGC31227.1 - 1.1e-06 27.7 0.3 7.9e-06 24.9 0.0 6.6 6 2 2 8 8 6 3 NMDA receptor-regulated protein 1 DUF3366 PF11846.3 EGC31227.1 - 0.0002 21.3 0.3 0.00083 19.2 0.2 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3366) TPR_3 PF07720.7 EGC31227.1 - 0.00073 19.2 8.3 0.04 13.7 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat CbiA PF01656.18 EGC31228.1 - 6.1e-30 104.0 0.1 8.2e-30 103.6 0.0 1.1 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGC31228.1 - 1.5e-15 57.5 0.0 2e-15 57.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain MipZ PF09140.6 EGC31228.1 - 2.5e-10 39.8 0.0 5.1e-10 38.8 0.0 1.4 1 1 0 1 1 1 1 ATPase MipZ ArsA_ATPase PF02374.10 EGC31228.1 - 9.7e-09 34.6 0.2 2.8e-08 33.1 0.1 1.7 2 0 0 2 2 2 1 Anion-transporting ATPase Fer4_NifH PF00142.13 EGC31228.1 - 8e-06 25.2 0.4 0.036 13.2 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family SRP54 PF00448.17 EGC31228.1 - 0.00016 21.1 1.0 0.016 14.6 0.5 2.5 2 1 0 2 2 2 1 SRP54-type protein, GTPase domain YhjQ PF06564.7 EGC31228.1 - 0.00027 20.3 0.0 0.0024 17.2 0.0 2.3 1 1 0 1 1 1 1 YhjQ protein AAA_26 PF13500.1 EGC31228.1 - 0.0022 17.6 2.3 1 8.9 0.0 3.0 2 1 0 2 2 2 2 AAA domain MobB PF03205.9 EGC31228.1 - 0.011 15.4 0.5 0.024 14.3 0.4 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_25 PF13481.1 EGC31228.1 - 0.016 14.6 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Med26 PF08711.6 EGC31228.1 - 0.066 12.7 0.0 0.15 11.6 0.0 1.5 1 0 0 1 1 1 0 TFIIS helical bundle-like domain AAA_17 PF13207.1 EGC31228.1 - 0.086 13.6 0.5 0.36 11.6 0.2 2.2 2 1 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGC31228.1 - 0.089 12.2 0.3 0.18 11.2 0.2 1.5 1 0 0 1 1 1 0 AAA-like domain NB-ARC PF00931.17 EGC31228.1 - 0.12 11.2 0.3 0.19 10.5 0.2 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_24 PF13479.1 EGC31228.1 - 0.13 11.8 0.4 0.26 10.8 0.3 1.5 1 1 0 1 1 1 0 AAA domain TPR_11 PF13414.1 EGC31229.1 - 2.1e-43 145.8 4.4 1.1e-10 40.9 0.1 5.4 4 1 1 5 5 5 4 TPR repeat TPR_1 PF00515.23 EGC31229.1 - 1.1e-35 119.8 12.7 1.5e-06 27.5 0.1 8.4 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31229.1 - 2e-34 114.7 3.2 4e-05 23.2 0.0 8.3 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31229.1 - 6.8e-25 86.8 5.7 7.1e-06 25.8 0.1 5.5 3 1 2 5 5 5 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31229.1 - 6.6e-23 80.8 0.0 3.8e-05 24.2 0.0 5.5 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31229.1 - 9e-22 75.1 15.3 2.2e-05 23.9 0.0 7.9 8 0 0 8 8 8 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31229.1 - 1.1e-20 73.6 1.2 2.1e-05 24.7 0.0 5.5 2 2 5 7 7 7 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31229.1 - 8.7e-19 66.3 0.0 0.083 13.5 0.0 7.8 3 3 5 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31229.1 - 5.5e-18 63.6 5.9 0.0011 18.9 0.1 7.0 7 1 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31229.1 - 1.3e-16 58.9 0.3 0.011 15.5 0.0 7.4 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC31229.1 - 6.2e-14 51.8 9.3 3.1e-06 27.2 0.4 4.4 1 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGC31229.1 - 3.1e-11 42.9 3.1 1.6 9.3 0.0 7.7 8 0 0 8 8 8 2 Tetratricopeptide repeat PPR PF01535.15 EGC31229.1 - 2.5e-05 23.9 0.3 0.8 9.8 0.0 5.6 7 0 0 7 7 5 1 PPR repeat MIT PF04212.13 EGC31229.1 - 6.3e-05 22.7 4.3 0.26 11.2 0.1 4.7 4 2 1 5 5 4 2 MIT (microtubule interacting and transport) domain TPR_21 PF09976.4 EGC31229.1 - 0.0004 20.3 0.6 0.24 11.3 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31229.1 - 0.00057 19.6 0.0 0.93 9.3 0.0 3.5 4 0 0 4 4 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EGC31229.1 - 0.0012 17.7 3.0 0.49 9.0 0.1 3.5 2 1 1 3 3 3 1 NMDA receptor-regulated protein 1 TPR_15 PF13429.1 EGC31229.1 - 0.0013 17.8 0.0 0.046 12.7 0.0 2.8 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31229.1 - 0.028 14.3 0.0 14 5.7 0.0 4.9 7 0 0 7 7 6 0 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGC31229.1 - 0.07 12.3 0.0 0.4 9.9 0.0 2.4 2 0 0 2 2 2 0 SHNi-TPR SNAP PF14938.1 EGC31229.1 - 0.14 11.3 5.5 0.51 9.4 0.3 3.3 3 2 0 3 3 3 0 Soluble NSF attachment protein, SNAP WD40 PF00400.27 EGC31231.1 - 1.5e-72 237.1 16.0 8.9e-13 47.5 0.1 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGC31231.1 - 0.00041 18.6 5.1 0.068 11.2 1.7 3.9 1 1 1 2 2 2 1 Nucleoporin Nup120/160 eIF2A PF08662.6 EGC31231.1 - 0.0008 19.1 0.3 0.051 13.2 0.1 2.9 1 1 2 4 4 4 2 Eukaryotic translation initiation factor eIF2A Nucleoporin_N PF08801.6 EGC31231.1 - 0.0043 15.8 5.4 3 6.4 0.3 4.1 1 1 2 3 3 3 2 Nup133 N terminal like Cytochrom_D1 PF02239.11 EGC31231.1 - 0.015 13.5 0.1 4.5 5.4 0.0 2.9 2 1 2 4 4 4 0 Cytochrome D1 heme domain IKI3 PF04762.7 EGC31231.1 - 0.019 12.8 0.1 0.22 9.3 0.0 2.5 2 2 1 3 3 3 0 IKI3 family LssY_C PF14067.1 EGC31231.1 - 0.07 12.1 0.2 0.94 8.4 0.0 2.5 2 1 1 3 3 3 0 LssY C-terminus GlcNAc PF11397.3 EGC31232.1 - 3.2e-83 279.6 0.0 8.8e-82 274.9 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase (GlcNAc) RP-C_C PF11800.3 EGC31233.1 - 4.9 6.7 7.9 10 5.7 5.5 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region TPR_2 PF07719.12 EGC31234.1 - 0.0087 15.9 1.2 0.38 10.7 0.0 3.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31234.1 - 0.057 13.3 0.2 0.057 13.3 0.1 4.0 4 1 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31234.1 - 0.091 12.5 3.6 0.53 10.2 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat ACP PF06857.6 EGC31234.1 - 0.16 11.9 0.4 0.72 9.8 0.1 2.2 2 0 0 2 2 2 0 Malonate decarboxylase delta subunit (MdcD) Cbl_N PF02262.11 EGC31235.1 - 0.019 14.6 0.0 6.1 6.5 0.0 2.4 2 0 0 2 2 2 0 CBL proto-oncogene N-terminal domain 1 Orthoreo_P10 PF07204.6 EGC31235.1 - 0.083 12.6 0.4 0.18 11.5 0.3 1.6 1 0 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 XET_C PF06955.7 EGC31236.1 - 0.094 12.4 0.7 1.1 9.0 0.5 2.3 1 1 0 1 1 1 0 Xyloglucan endo-transglycosylase (XET) C-terminus RhoGAP PF00620.22 EGC31237.1 - 1.4e-33 115.6 0.3 1.4e-33 115.6 0.2 2.9 3 0 0 3 3 3 1 RhoGAP domain CK2S PF15011.1 EGC31237.1 - 0.00069 19.4 1.3 0.0088 15.8 0.1 2.7 2 0 0 2 2 2 1 Casein Kinase 2 substrate DUF1548 PF07579.6 EGC31237.1 - 4.2 7.4 9.4 0.71 9.9 0.6 3.3 2 1 1 3 3 3 0 Domain of Unknown Function (DUF1548) TGT PF01702.13 EGC31238.1 - 1.8e-69 233.6 0.0 2.4e-69 233.2 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Invasin_D3 PF09134.5 EGC31238.1 - 0.017 14.9 0.0 0.057 13.2 0.0 1.8 1 0 0 1 1 1 0 Invasin, domain 3 Bromodomain PF00439.20 EGC31240.1 - 1.4e-19 69.7 0.5 1.4e-19 69.7 0.4 2.9 2 0 0 2 2 2 1 Bromodomain LrgB PF04172.11 EGC31240.1 - 0.64 9.1 0.4 1.3 8.1 0.3 1.4 1 0 0 1 1 1 0 LrgB-like family YibE_F PF07907.6 EGC31241.1 - 0.013 14.7 2.2 0.013 14.7 1.5 1.7 1 1 0 1 1 1 0 YibE/F-like protein DUF2207 PF09972.4 EGC31241.1 - 9.5 4.6 8.5 0.62 8.5 2.2 1.6 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) WH2 PF02205.15 EGC31242.1 - 8.5e-06 25.2 0.0 1.4e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 WH2 motif NOG1 PF06858.9 EGC31243.1 - 2.1e-25 88.3 0.6 5.7e-25 86.9 0.4 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) MMR_HSR1 PF01926.18 EGC31243.1 - 1.9e-18 66.4 0.0 6e-18 64.9 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase NOGCT PF08155.6 EGC31243.1 - 3.5e-16 58.6 3.0 1.3e-15 56.7 2.1 2.0 1 0 0 1 1 1 1 NOGCT (NUC087) domain FeoB_N PF02421.13 EGC31243.1 - 1.2e-11 44.1 0.0 2.6e-11 43.0 0.0 1.6 1 0 0 1 1 1 1 Ferrous iron transport protein B Miro PF08477.8 EGC31243.1 - 0.00014 22.3 0.0 0.0006 20.2 0.0 2.2 2 0 0 2 2 1 1 Miro-like protein AIG1 PF04548.11 EGC31243.1 - 0.0037 16.3 0.1 0.017 14.1 0.0 2.2 3 0 0 3 3 3 1 AIG1 family SRPRB PF09439.5 EGC31243.1 - 0.0075 15.5 1.1 0.039 13.1 0.0 2.7 3 0 0 3 3 3 1 Signal recognition particle receptor beta subunit DUF258 PF03193.11 EGC31243.1 - 0.017 14.3 0.0 0.075 12.2 0.0 2.0 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_18 PF13238.1 EGC31243.1 - 0.049 13.9 5.1 2.2 8.6 0.0 3.0 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC31243.1 - 0.051 13.5 0.8 0.66 9.9 0.0 3.0 4 0 0 4 4 4 0 AAA ATPase domain ArgK PF03308.11 EGC31243.1 - 0.12 11.0 0.4 0.71 8.6 0.0 2.4 3 0 0 3 3 3 0 ArgK protein DNA_pol_alpha_N PF12254.3 EGC31243.1 - 0.15 11.8 7.1 0.093 12.5 1.0 3.0 3 0 0 3 3 2 0 DNA polymerase alpha subunit p180 N terminal Dynamin_N PF00350.18 EGC31243.1 - 0.17 11.7 4.2 6.4 6.5 0.0 3.5 2 1 1 3 3 3 0 Dynamin family Corona_nucleoca PF00937.13 EGC31243.1 - 0.53 9.1 12.2 0.37 9.7 7.2 1.6 1 1 0 1 1 1 0 Coronavirus nucleocapsid protein AAA_17 PF13207.1 EGC31243.1 - 3.4 8.5 0.0 3.4 8.5 0.0 3.3 2 1 0 2 2 1 0 AAA domain Pkinase_Tyr PF07714.12 EGC31244.1 - 7e-55 185.8 0.0 1e-54 185.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC31244.1 - 1.5e-49 168.5 0.0 2.4e-49 167.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Tmemb_40 PF10160.4 EGC31244.1 - 1.3e-05 24.5 2.8 3e-05 23.3 1.9 1.6 1 0 0 1 1 1 1 Predicted membrane protein FKBP_C PF00254.23 EGC31245.1 - 2.1e-24 85.3 0.0 2.4e-24 85.1 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase LRR_4 PF12799.2 EGC31246.1 - 1.6e-05 24.4 1.0 1.6e-05 24.4 0.7 6.2 6 1 0 6 6 6 2 Leucine Rich repeats (2 copies) Ion_trans PF00520.26 EGC31247.1 - 0.017 14.3 0.1 0.017 14.3 0.0 1.2 1 0 0 1 1 1 0 Ion transport protein DUF4405 PF14358.1 EGC31247.1 - 0.21 11.7 1.6 0.32 11.1 1.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4405) DUF3675 PF12428.3 EGC31247.1 - 0.7 10.1 8.9 0.26 11.5 3.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3675) AAA_23 PF13476.1 EGC31247.1 - 6.3 7.0 23.1 9.2 6.5 16.0 1.3 1 0 0 1 1 1 0 AAA domain Amidohydro_1 PF01979.15 EGC31250.1 - 4e-44 151.6 0.9 5.3e-44 151.2 0.6 1.2 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_3 PF07969.6 EGC31250.1 - 1.9e-14 53.7 0.1 1.7e-12 47.2 0.0 2.1 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGC31250.1 - 7.8e-11 42.5 0.0 2.8e-08 34.1 0.0 2.2 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_5 PF13594.1 EGC31250.1 - 0.0016 18.1 0.9 0.0099 15.6 0.0 2.8 2 2 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 EGC31250.1 - 0.007 15.3 0.0 0.016 14.1 0.0 1.6 2 0 0 2 2 2 1 Adenosine/AMP deaminase Alpha-amyl_C PF09071.5 EGC31250.1 - 0.066 12.9 0.1 0.16 11.7 0.0 1.6 1 0 0 1 1 1 0 Alpha-amylase, C terminal DUF3430 PF11912.3 EGC31251.1 - 3e-32 112.1 36.0 3e-32 112.1 24.9 3.6 1 1 1 3 3 3 1 Protein of unknown function (DUF3430) DUF4002 PF13164.1 EGC31251.1 - 4.5 7.3 23.5 7.8 6.5 5.0 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4002) RhoGEF PF00621.15 EGC31252.1 - 1.3e-45 155.5 4.2 1.3e-45 155.5 2.9 2.2 2 0 0 2 2 2 1 RhoGEF domain Arm PF00514.18 EGC31252.1 - 1.3e-16 59.7 13.0 0.00062 19.4 0.0 8.8 9 0 0 9 9 9 3 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC31252.1 - 6.7e-07 29.4 3.2 0.00047 20.3 0.2 4.8 5 0 0 5 5 5 1 HEAT repeats PH PF00169.24 EGC31252.1 - 0.00071 19.7 0.0 0.0024 18.0 0.0 2.0 1 0 0 1 1 1 1 PH domain HEAT_EZ PF13513.1 EGC31252.1 - 0.029 14.8 7.3 3.4 8.2 0.4 4.8 4 1 1 5 5 5 0 HEAT-like repeat AKAP7_NLS PF10469.4 EGC31255.1 - 2.3e-30 105.8 1.7 2.9e-30 105.5 1.2 1.1 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EGC31255.1 - 4e-06 26.6 0.0 5.3e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily LigT_PEase PF02834.11 EGC31255.1 - 2.7e-05 24.0 0.1 0.21 11.5 0.0 2.8 2 1 0 2 2 2 2 LigT like Phosphoesterase Corona_NS2A PF05213.7 EGC31255.1 - 4e-05 23.0 1.1 0.00056 19.3 0.8 2.0 1 1 0 1 1 1 1 Coronavirus NS2A protein HVSL PF09749.4 EGC31255.1 - 0.0092 15.0 0.8 0.029 13.4 0.3 1.7 1 1 1 2 2 2 1 Uncharacterised conserved protein PEN-2 PF10251.4 EGC31256.1 - 1.8e-17 63.2 9.0 2.3e-17 62.9 6.2 1.1 1 0 0 1 1 1 1 Presenilin enhancer-2 subunit of gamma secretase DPM3 PF08285.6 EGC31256.1 - 0.13 12.1 2.2 0.14 11.9 1.5 1.1 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) DUF2207 PF09972.4 EGC31256.1 - 2.8 6.4 5.3 3.1 6.2 3.7 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Metallophos_C PF14008.1 EGC31257.1 - 7.5e-18 64.3 0.5 3e-17 62.4 0.1 2.2 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EGC31257.1 - 5.8e-13 48.6 5.4 3.8e-12 46.0 3.7 2.2 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EGC31257.1 - 5.6e-06 25.1 0.5 9.2e-06 24.4 0.3 1.3 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EGC31257.1 - 1.1e-05 25.3 0.0 1.9e-05 24.5 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Apc4_WD40 PF12894.2 EGC31258.1 - 1.4e-05 24.4 0.0 0.17 11.4 0.0 2.8 2 0 0 2 2 2 2 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EGC31258.1 - 0.00031 20.4 1.2 3.4 7.6 0.0 4.7 5 0 0 5 5 5 1 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC31258.1 - 0.0014 18.3 1.8 0.17 11.6 0.1 3.9 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region BBS2_N PF14781.1 EGC31259.1 - 0.0071 15.9 3.2 0.27 10.8 0.2 2.8 1 1 2 3 3 3 2 Ciliary BBSome complex subunit 2, N-terminal Peptidase_S30 PF01577.11 EGC31259.1 - 0.072 12.4 0.2 0.11 11.8 0.2 1.3 1 0 0 1 1 1 0 Potyvirus P1 protease BSP_II PF05432.6 EGC31259.1 - 4.8 6.3 8.8 1.6 7.9 2.5 2.0 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) DUF2961 PF11175.3 EGC31262.1 - 0.014 14.7 0.1 0.016 14.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2961) GBS_Bsp-like PF08481.5 EGC31262.1 - 0.1 12.4 0.1 0.12 12.2 0.1 1.1 1 0 0 1 1 1 0 GBS Bsp-like repeat Sex_peptide PF08138.6 EGC31262.1 - 0.13 12.1 0.1 0.28 11.0 0.0 1.7 1 1 0 1 1 1 0 Sex peptide (SP) family Toxin_46 PF15526.1 EGC31263.1 - 0.11 12.6 0.6 0.16 12.1 0.4 1.3 1 0 0 1 1 1 0 Putative toxin 46 DUF1940 PF09155.5 EGC31265.1 - 0.035 13.9 0.8 9.3 6.0 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF1940) Methyltransf_16 PF10294.4 EGC31266.1 - 1e-27 96.6 3.9 1.4e-16 60.4 0.1 2.1 1 1 1 2 2 2 2 Putative methyltransferase Methyltransf_23 PF13489.1 EGC31266.1 - 2.5e-08 33.8 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC31266.1 - 0.0003 20.1 0.2 0.021 14.2 0.0 2.2 1 1 1 2 2 2 2 Methyltransferase small domain Methyltransf_18 PF12847.2 EGC31266.1 - 0.00078 20.0 0.0 0.0024 18.4 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC31266.1 - 0.0009 18.8 1.2 0.0096 15.5 0.8 2.1 1 1 0 1 1 1 1 Methyltransferase domain GidB PF02527.10 EGC31266.1 - 0.0011 18.2 0.1 0.051 12.7 0.0 2.3 1 1 1 2 2 2 1 rRNA small subunit methyltransferase G Methyltransf_26 PF13659.1 EGC31266.1 - 0.0017 18.4 0.0 0.0034 17.4 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC31266.1 - 0.0028 18.0 0.3 0.051 14.0 0.3 2.5 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGC31266.1 - 0.0035 16.4 0.5 0.012 14.7 0.1 1.8 1 1 1 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) UPF0066 PF01980.11 EGC31267.1 - 3.5e-37 127.0 0.0 6.5e-37 126.1 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised protein family UPF0066 COX16 PF14138.1 EGC31267.1 - 0.04 14.0 0.7 0.04 14.0 0.5 2.2 2 1 0 2 2 2 0 Cytochrome c oxidase assembly protein COX16 DUF3278 PF11683.3 EGC31267.1 - 0.065 13.2 0.2 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3278) MIG-14_Wnt-bd PF06664.7 EGC31269.1 - 1.1e-62 211.6 25.5 1.7e-62 210.9 17.7 1.3 1 0 0 1 1 1 1 Wnt-binding factor required for Wnt secretion MCLC PF05934.6 EGC31269.1 - 0.045 12.0 0.5 0.078 11.2 0.3 1.3 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Histone PF00125.19 EGC31270.1 - 2.1e-10 40.5 0.2 4.7e-10 39.4 0.1 1.6 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC31270.1 - 0.00093 19.2 0.0 0.003 17.5 0.0 2.0 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Mitochondr_Som1 PF11093.3 EGC31271.1 - 0.065 13.0 0.1 0.072 12.9 0.1 1.4 1 0 0 1 1 1 0 Mitochondrial export protein Som1 IMS PF00817.15 EGC31275.1 - 3.3e-40 137.2 0.0 6.6e-40 136.3 0.0 1.5 1 0 0 1 1 1 1 impB/mucB/samB family IMS_HHH PF11798.3 EGC31275.1 - 1.5e-05 24.7 0.2 4.2e-05 23.3 0.1 1.8 1 0 0 1 1 1 1 IMS family HHH motif Caps_synth_GfcC PF06251.6 EGC31275.1 - 0.0004 19.6 0.0 0.012 14.7 0.0 2.2 1 1 1 2 2 2 1 Capsule biosynthesis GfcC DUF4331 PF14224.1 EGC31275.1 - 0.12 11.5 0.8 0.18 10.9 0.0 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4331) GN3L_Grn1 PF08701.6 EGC31276.1 - 2.9e-22 78.3 19.2 2.9e-22 78.3 13.3 4.6 3 2 1 4 4 4 1 GNL3L/Grn1 putative GTPase MMR_HSR1 PF01926.18 EGC31276.1 - 1.2e-16 60.7 12.5 2.1e-14 53.4 0.1 3.7 4 1 0 4 4 4 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC31276.1 - 2.8e-11 42.9 4.9 1.4e-07 30.8 0.1 2.9 3 0 0 3 3 3 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGC31276.1 - 2.4e-05 23.8 3.0 0.00058 19.3 0.0 3.4 3 1 1 4 4 4 1 Elongation factor Tu GTP binding domain DUF258 PF03193.11 EGC31276.1 - 0.0023 17.1 1.8 0.0043 16.2 0.2 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC31276.1 - 1.3 9.5 12.4 1.1 9.8 0.0 3.8 3 2 0 3 3 3 0 Miro-like protein AAA_17 PF13207.1 EGC31276.1 - 1.9 9.3 0.0 1.9 9.3 0.0 3.9 3 2 0 3 3 3 0 AAA domain ArgK PF03308.11 EGC31276.1 - 2.9 6.5 11.1 0.76 8.5 0.0 3.3 3 0 0 3 3 3 0 ArgK protein AAA_16 PF13191.1 EGC31276.1 - 5.1 7.0 7.6 1.2 9.0 0.1 2.9 3 2 0 3 3 3 0 AAA ATPase domain RRM_1 PF00076.17 EGC31278.1 - 1.6e-12 46.8 0.2 2.5e-12 46.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31278.1 - 1e-09 38.2 0.0 1.8e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31278.1 - 6.9e-09 35.4 0.1 1e-08 34.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EGC31278.1 - 1.7e-05 24.4 3.2 1.7e-05 24.4 2.2 1.8 2 0 0 2 2 2 1 Zinc knuckle MIP-T3 PF10243.4 EGC31278.1 - 0.039 12.4 42.6 0.051 12.0 29.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 PP2C PF00481.16 EGC31279.1 - 3.9e-65 219.7 0.1 3.9e-65 219.7 0.1 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C Macoilin PF09726.4 EGC31279.1 - 1.1 7.4 14.6 1.1 7.4 10.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Lin-8 PF03353.10 EGC31279.1 - 2.5 7.3 19.9 4.1 6.5 13.8 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist TP53IP5 PF15331.1 EGC31279.1 - 8.5 6.2 13.7 14 5.4 9.5 1.4 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 Sel1 PF08238.7 EGC31280.1 - 0.00022 21.7 1.7 15 6.3 0.0 4.6 5 0 0 5 5 5 2 Sel1 repeat TPR_11 PF13414.1 EGC31280.1 - 0.00046 19.7 0.2 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 TPR repeat TPR_19 PF14559.1 EGC31280.1 - 0.00091 19.5 0.5 0.0044 17.3 0.0 2.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31280.1 - 0.0034 17.2 0.1 0.011 15.6 0.0 1.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31280.1 - 0.0091 16.1 0.1 0.031 14.4 0.1 2.0 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31280.1 - 0.03 15.0 0.0 0.11 13.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31280.1 - 0.03 14.2 0.1 1.1 9.3 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC31280.1 - 0.054 13.1 0.6 6.8 6.4 0.0 3.0 2 0 0 2 2 2 0 Tetratricopeptide repeat G8 PF10162.4 EGC31281.1 - 7.8e-29 100.0 1.1 1.4e-28 99.2 0.0 2.0 2 0 0 2 2 2 1 G8 domain TPR_17 PF13431.1 EGC31282.1 - 1.2e-07 31.3 7.5 0.0013 18.7 0.1 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat PH_4 PF15404.1 EGC31282.1 - 0.0023 17.4 1.0 0.0031 17.0 0.7 1.3 1 0 0 1 1 1 1 Pleckstrin homology domain TPR_11 PF13414.1 EGC31282.1 - 0.01 15.4 0.1 0.01 15.4 0.1 3.6 4 0 0 4 4 4 0 TPR repeat Cas_Cmr3 PF09700.5 EGC31282.1 - 1 8.7 4.3 5.2 6.3 2.0 2.0 1 1 1 2 2 2 0 CRISPR-associated protein (Cas_Cmr3) Symplekin_C PF12295.3 EGC31283.1 - 4.2e-51 173.4 2.8 4.2e-51 173.4 2.0 3.3 2 1 0 2 2 2 1 Symplekin tight junction protein C terminal DUF3453 PF11935.3 EGC31283.1 - 2.7e-42 144.8 10.7 2.7e-42 144.8 7.4 2.9 3 0 0 3 3 3 2 Domain of unknown function (DUF3453) PCI PF01399.22 EGC31284.1 - 1.1e-17 64.2 2.5 1.2e-17 64.0 0.2 2.2 2 1 0 2 2 2 1 PCI domain Mucin PF01456.12 EGC31285.1 - 5.3e-06 26.2 16.7 6.9e-06 25.8 11.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein TMEM154 PF15102.1 EGC31285.1 - 0.004 16.8 7.8 0.0054 16.4 4.6 1.9 1 1 0 1 1 1 1 TMEM154 protein family EMP24_GP25L PF01105.19 EGC31286.1 - 0.062 13.0 4.3 0.068 12.8 3.0 1.2 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD Sif PF06767.6 EGC31286.1 - 0.073 11.8 2.1 0.93 8.1 0.2 2.1 1 1 0 2 2 2 0 Sif protein PH PF00169.24 EGC31286.1 - 9.2 6.5 8.6 1.3e+02 2.8 5.9 2.4 1 1 0 1 1 1 0 PH domain Glyco_hydro_9 PF00759.14 EGC31287.1 - 4.5e-137 457.5 8.6 5.1e-137 457.3 6.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 DUF1680 PF07944.7 EGC31287.1 - 0.037 12.3 0.1 0.081 11.1 0.0 1.6 1 0 0 1 1 1 0 Putative glycosyl hydrolase of unknown function (DUF1680) CHASE3 PF05227.8 EGC31289.1 - 1.3 8.6 9.1 1.5 8.4 3.0 2.2 1 1 1 2 2 2 0 CHASE3 domain SPT16 PF08644.6 EGC31289.1 - 3.7 7.3 18.1 2.9 7.6 7.1 2.4 1 1 1 2 2 2 0 FACT complex subunit (SPT16/CDC68) Tweety PF04906.8 EGC31289.1 - 5.7 5.2 6.3 8.7 4.6 4.4 1.2 1 0 0 1 1 1 0 Tweety Med25_VWA PF11265.3 EGC31290.1 - 9.3e-07 28.0 0.0 1.9e-06 27.0 0.0 1.5 1 0 0 1 1 1 1 Mediator complex subunit 25 von Willebrand factor type A G10 PF01125.12 EGC31291.1 - 0.0061 16.1 12.8 0.0061 16.1 8.8 4.7 3 1 1 4 4 4 2 G10 protein DUF4398 PF14346.1 EGC31292.1 - 0.49 10.4 4.2 15 5.7 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) Sec5 PF15469.1 EGC31294.1 - 1e-47 162.1 8.0 1e-47 162.1 5.5 3.1 2 1 0 2 2 2 1 Exocyst complex component Sec5 GCK PF07802.6 EGC31294.1 - 0.045 13.8 3.2 0.12 12.4 0.1 3.1 2 0 0 2 2 2 0 GCK domain Ank_2 PF12796.2 EGC31295.1 - 8.4e-09 35.6 0.2 8.4e-09 35.6 0.1 3.6 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC31295.1 - 1e-06 29.0 2.7 0.0054 17.2 0.1 3.4 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC31295.1 - 4.3e-06 26.4 3.1 1.9 8.9 0.1 5.2 3 1 2 5 5 5 2 Ankyrin repeat Ank_5 PF13857.1 EGC31295.1 - 0.0011 19.1 0.9 0.09 13.0 0.2 6.5 4 2 3 7 7 7 2 Ankyrin repeats (many copies) Asparaginase PF00710.15 EGC31295.1 - 0.062 12.1 0.1 0.11 11.4 0.1 1.2 1 0 0 1 1 1 0 Asparaginase SprA-related PF12118.3 EGC31295.1 - 2.2 7.5 7.7 3.3 6.9 5.3 1.3 1 0 0 1 1 1 0 SprA-related family zf-RING_2 PF13639.1 EGC31296.1 - 1.5e-10 40.7 12.4 1.7e-10 40.5 6.7 2.3 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31296.1 - 1.4e-07 31.0 6.9 1.4e-07 31.0 4.8 1.8 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31296.1 - 3.4e-07 29.7 10.5 3.4e-07 29.7 7.2 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31296.1 - 2.1e-06 27.6 12.2 2.4e-06 27.4 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31296.1 - 0.0001 22.3 6.9 0.00026 21.0 4.8 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC31296.1 - 0.00027 20.5 8.0 0.00027 20.5 5.6 2.4 3 0 0 3 3 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC31296.1 - 0.00092 19.0 9.0 0.00092 19.0 6.3 2.4 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC31296.1 - 0.0062 16.0 10.7 0.016 14.7 7.4 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC31296.1 - 0.048 13.5 2.1 0.11 12.3 1.5 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC31296.1 - 0.049 13.3 4.4 0.22 11.2 3.0 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGC31296.1 - 0.16 11.7 1.8 0.39 10.5 1.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EGC31296.1 - 0.59 9.7 6.5 1.7 8.2 4.5 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EGC31296.1 - 0.9 9.0 9.0 2.1 7.9 6.2 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_3 PF14369.1 EGC31296.1 - 3.2 7.8 11.4 0.34 10.9 4.7 1.8 2 0 0 2 2 2 0 zinc-finger TM2 PF05154.11 EGC31297.1 - 1.3e-18 66.9 8.6 1.6e-18 66.6 6.0 1.1 1 0 0 1 1 1 1 TM2 domain BioY PF02632.9 EGC31297.1 - 0.02 14.5 0.1 0.026 14.1 0.0 1.1 1 0 0 1 1 1 0 BioY family Shisa PF13908.1 EGC31297.1 - 0.32 11.1 5.9 0.52 10.4 4.1 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PAT1 PF09770.4 EGC31297.1 - 9.2 4.3 21.5 10 4.2 14.9 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 EGF_2 PF07974.8 EGC31298.1 - 8e-11 41.9 59.5 5.9e-06 26.3 9.6 3.8 3 0 0 3 3 3 3 EGF-like domain Tme5_EGF_like PF09064.5 EGC31298.1 - 0.0041 16.6 4.0 0.0041 16.6 2.8 4.0 2 1 1 3 3 3 1 Thrombomodulin like fifth domain, EGF-like Cadherin_2 PF08266.7 EGC31298.1 - 0.19 11.2 1.3 0.53 9.8 0.1 2.3 3 0 0 3 3 3 0 Cadherin-like CAF1 PF04857.15 EGC31299.1 - 6.2e-43 147.0 20.4 1.3e-42 145.9 14.1 1.6 1 1 0 1 1 1 1 CAF1 family ribonuclease DNA_pol_A_exo1 PF01612.15 EGC31299.1 - 0.00029 20.3 1.7 0.069 12.6 0.4 2.4 2 0 0 2 2 2 2 3'-5' exonuclease Methyltransf_12 PF08242.7 EGC31301.1 - 5.1e-14 52.5 0.1 2.3e-13 50.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC31301.1 - 6.3e-14 52.0 0.0 8.8e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC31301.1 - 3.4e-10 40.4 0.0 6.5e-10 39.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC31301.1 - 9.1e-10 38.3 0.0 1.5e-09 37.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC31301.1 - 1.3e-07 32.0 0.0 2.6e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC31301.1 - 1.6e-07 31.5 0.0 3.4e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC31301.1 - 2.8e-05 24.1 0.0 5.4e-05 23.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC31301.1 - 4.4e-05 22.7 0.1 5.7e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family CheR PF01739.13 EGC31301.1 - 0.00053 19.3 0.1 1 8.6 0.0 2.5 2 0 0 2 2 2 2 CheR methyltransferase, SAM binding domain MTS PF05175.9 EGC31301.1 - 0.0015 17.9 0.0 0.0029 16.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_PK PF05891.7 EGC31301.1 - 0.0017 17.6 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_24 PF13578.1 EGC31301.1 - 0.034 14.9 0.0 0.099 13.4 0.0 1.8 2 0 0 2 2 1 0 Methyltransferase domain TPMT PF05724.6 EGC31301.1 - 0.059 12.7 0.0 0.084 12.3 0.0 1.2 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) FmrO PF07091.6 EGC31301.1 - 0.1 11.5 0.0 0.18 10.7 0.0 1.4 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) GCN5L1 PF06320.8 EGC31302.1 - 8.1e-48 161.2 3.9 9.7e-48 160.9 2.7 1.1 1 0 0 1 1 1 1 GCN5-like protein 1 (GCN5L1) DUF4588 PF15251.1 EGC31302.1 - 0.011 15.7 0.3 0.02 14.8 0.0 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4588) DUF3972 PF13118.1 EGC31302.1 - 0.062 13.3 1.7 0.078 13.0 0.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3972) DivIC PF04977.10 EGC31302.1 - 0.12 11.9 0.2 0.12 11.9 0.2 2.7 3 0 0 3 3 3 0 Septum formation initiator IncA PF04156.9 EGC31302.1 - 0.12 11.9 5.5 1.2 8.6 1.0 2.1 2 0 0 2 2 2 0 IncA protein GAS PF13851.1 EGC31302.1 - 0.42 9.7 6.4 0.7 9.0 4.4 1.3 1 1 0 1 1 1 0 Growth-arrest specific micro-tubule binding DUF948 PF06103.6 EGC31302.1 - 0.82 9.5 5.4 5.6 6.8 0.3 2.8 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) XhlA PF10779.4 EGC31302.1 - 0.94 9.4 7.4 0.6 10.0 1.6 2.3 2 1 0 2 2 2 0 Haemolysin XhlA K-box PF01486.12 EGC31302.1 - 1.8 8.4 7.7 1.5 8.6 2.8 2.6 1 1 0 1 1 1 0 K-box region Herpes_BLRF2 PF05812.7 EGC31302.1 - 2.7 7.8 5.6 5.1 6.9 3.9 1.8 1 1 0 1 1 1 0 Herpesvirus BLRF2 protein Ax_dynein_light PF10211.4 EGC31302.1 - 5.7 6.7 7.3 13 5.5 1.0 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Myb_DNA-binding PF00249.26 EGC31303.1 - 1e-10 41.5 0.2 2.6e-09 37.0 0.0 2.5 2 0 0 2 2 2 1 Myb-like DNA-binding domain ZZ PF00569.12 EGC31303.1 - 1e-09 37.7 3.6 2.2e-09 36.6 2.5 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type SWIRM PF04433.12 EGC31303.1 - 4.9e-09 36.2 0.9 5.3e-08 32.8 0.1 2.6 2 0 0 2 2 2 1 SWIRM domain Glyco_hydro_18 PF00704.23 EGC31304.1 - 2.4e-22 79.8 0.1 3.4e-22 79.3 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 EamA PF00892.15 EGC31305.1 - 4.3e-12 46.1 33.2 3.9e-06 26.9 6.0 3.2 3 0 0 3 3 3 3 EamA-like transporter family DUF914 PF06027.7 EGC31305.1 - 1.1e-09 37.6 15.4 2e-09 36.7 10.7 1.4 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EGC31305.1 - 3.5e-08 33.2 24.4 0.00021 20.9 5.4 2.9 2 1 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EGC31305.1 - 6.1e-07 29.6 18.9 3.3e-05 24.0 0.4 3.3 3 1 0 3 3 3 2 Multidrug resistance efflux transporter UAA PF08449.6 EGC31305.1 - 0.0046 15.9 19.9 0.0076 15.2 11.6 2.1 2 0 0 2 2 2 1 UAA transporter family EF-hand_1 PF00036.27 EGC31306.1 - 9.8e-13 46.4 11.6 0.00011 21.2 0.1 5.0 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EGC31306.1 - 6.1e-11 41.7 13.1 0.00049 19.6 0.6 4.0 3 2 1 4 4 4 3 EF-hand domain pair EF-hand_7 PF13499.1 EGC31306.1 - 1.5e-09 37.8 8.6 2.2e-06 27.7 2.7 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC31306.1 - 1.6e-09 36.8 10.7 0.0054 16.5 0.1 4.6 4 0 0 4 4 4 3 EF-hand domain EF-hand_4 PF12763.2 EGC31306.1 - 1e-05 25.2 6.1 0.059 13.1 0.2 3.2 1 1 2 3 3 3 2 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGC31306.1 - 0.00022 21.0 0.0 1.1 9.1 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain EF-hand_5 PF13202.1 EGC31306.1 - 0.00075 18.7 10.2 1.5 8.3 0.0 4.6 4 0 0 4 4 4 2 EF hand Myb_DNA-binding PF00249.26 EGC31307.1 - 1e-32 111.9 11.3 6.1e-14 51.7 0.6 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC31307.1 - 3.2e-30 103.9 8.7 9.5e-17 60.8 0.4 3.8 2 1 1 3 3 3 3 Myb-like DNA-binding domain Rap1_C PF11626.3 EGC31307.1 - 0.11 12.4 1.2 1.4 8.8 0.2 2.8 3 0 0 3 3 3 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain MADF_DNA_bdg PF10545.4 EGC31307.1 - 7.4 6.8 7.6 3.5 7.8 0.1 3.1 2 1 1 3 3 3 0 Alcohol dehydrogenase transcription factor Myb/SANT-like WD40 PF00400.27 EGC31308.1 - 4.7e-28 96.0 23.5 3.9e-07 29.7 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat PspA_IM30 PF04012.7 EGC31308.1 - 0.051 12.9 1.8 0.082 12.2 1.2 1.2 1 0 0 1 1 1 0 PspA/IM30 family Speriolin_C PF15059.1 EGC31308.1 - 0.1 12.6 0.3 0.25 11.3 0.2 1.6 1 0 0 1 1 1 0 Speriolin C-terminus DUF1765 PF08578.5 EGC31309.1 - 4e-24 85.0 5.5 4e-24 85.0 3.8 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1765) Vault PF01505.13 EGC31310.1 - 6.9e-66 218.0 0.1 1.1e-14 54.1 0.0 6.7 7 0 0 7 7 7 5 Major Vault Protein repeat MVP_shoulder PF11978.3 EGC31310.1 - 2.2e-54 182.3 0.9 4.7e-54 181.3 0.6 1.6 1 0 0 1 1 1 1 Shoulder domain tRNA-synt_His PF13393.1 EGC31311.1 - 1.8e-39 135.6 0.0 3.1e-39 134.8 0.0 1.4 1 1 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGC31311.1 - 4.9e-26 91.3 0.0 9.6e-26 90.3 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC31311.1 - 1.2e-09 37.9 0.0 7.4e-09 35.4 0.0 2.1 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGC31311.1 - 0.0036 16.1 0.0 0.057 12.1 0.0 2.3 1 1 0 1 1 1 1 tRNA synthetases class II (D, K and N) RRP7 PF12923.2 EGC31312.1 - 2.1e-27 95.7 12.9 2.1e-27 95.7 8.9 4.1 3 2 1 4 4 4 1 Ribosomal RNA-processing protein 7 (RRP7) Trypan_PARP PF05887.6 EGC31312.1 - 2.6 7.8 28.2 0.018 14.8 13.4 1.9 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) Kin17_mid PF10357.4 EGC31313.1 - 8.5e-45 151.4 5.8 8.5e-45 151.4 4.0 2.5 2 0 0 2 2 2 1 Domain of Kin17 curved DNA-binding protein zf-met PF12874.2 EGC31313.1 - 0.00026 21.0 3.7 0.00059 19.9 2.5 1.7 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGC31313.1 - 0.00047 20.2 4.3 0.00047 20.2 3.0 2.6 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGC31313.1 - 0.023 14.8 0.5 0.023 14.8 0.3 2.8 3 0 0 3 3 3 0 C2H2 type zinc-finger (2 copies) KOW PF00467.24 EGC31313.1 - 0.065 12.9 0.1 0.2 11.4 0.1 1.8 1 0 0 1 1 1 0 KOW motif MMtag PF10159.4 EGC31313.1 - 5.6 7.0 11.1 0.64 10.1 0.9 3.2 3 0 0 3 3 3 0 Kinase phosphorylation protein SpoU_methylase PF00588.14 EGC31314.1 - 4.6e-29 101.1 0.9 1.2e-13 51.0 0.3 2.3 1 1 1 2 2 2 2 SpoU rRNA Methylase family RNA_pol_Rpb5_N PF03871.9 EGC31314.1 - 0.096 13.1 0.1 0.3 11.5 0.0 1.8 1 1 0 1 1 1 0 RNA polymerase Rpb5, N-terminal domain Sep15_SelM PF08806.6 EGC31315.1 - 2.1e-09 37.0 0.1 2.7e-09 36.6 0.0 1.2 1 0 0 1 1 1 1 Sep15/SelM redox domain DUF3430 PF11912.3 EGC31317.1 - 8.7e-28 97.5 32.5 9.7e-28 97.4 22.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) PLA2_B PF01735.13 EGC31318.1 - 0.37 8.8 3.2 0.43 8.6 2.2 1.1 1 0 0 1 1 1 0 Lysophospholipase catalytic domain ABC2_membrane_3 PF12698.2 EGC31318.1 - 7.7 5.4 6.5 8.9 5.2 4.5 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF4406 PF14359.1 EGC31319.1 - 0.023 14.7 0.3 8.9 6.4 0.0 3.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4406) DUF1183 PF06682.7 EGC31319.1 - 0.21 11.1 14.1 0.33 10.5 9.8 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) IL12p40_C PF10420.4 EGC31319.1 - 2.6 8.2 5.8 2.1 8.5 2.3 2.3 1 1 0 1 1 1 0 Cytokine interleukin-12p40 C-terminus CH PF00307.26 EGC31320.1 - 1e-11 44.8 0.8 1e-11 44.8 0.6 2.1 3 0 0 3 3 3 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC31320.1 - 0.036 13.7 0.3 0.12 11.9 0.2 1.9 1 0 0 1 1 1 0 CAMSAP CH domain SR-25 PF10500.4 EGC31321.1 - 5.1e-15 55.5 0.3 5.6e-15 55.4 0.2 1.0 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Auto_anti-p27 PF06677.7 EGC31322.1 - 4.3e-21 74.3 3.5 2e-11 43.4 0.1 2.4 2 0 0 2 2 2 2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Pox_RNA_pol PF03293.9 EGC31322.1 - 0.023 14.2 1.2 0.046 13.2 0.8 1.4 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase, 18 kD subunit E6 PF00518.12 EGC31322.1 - 0.04 14.2 1.8 0.076 13.3 0.4 2.2 2 0 0 2 2 2 0 Early Protein (E6) PHD PF00628.24 EGC31322.1 - 2.1 8.0 7.3 4.9 6.9 0.4 2.6 2 0 0 2 2 2 0 PHD-finger SprA-related PF12118.3 EGC31323.1 - 8.3 5.6 35.0 0.85 8.8 13.8 2.1 2 0 0 2 2 2 0 SprA-related family FNIP PF05725.7 EGC31324.1 - 1.9e-11 43.7 17.2 9.4e-07 28.6 0.2 6.2 3 2 2 5 5 5 3 FNIP Repeat YfhO PF09586.5 EGC31325.1 - 0.044 11.8 0.2 0.046 11.7 0.2 1.0 1 0 0 1 1 1 0 Bacterial membrane protein YfhO FNIP PF05725.7 EGC31326.1 - 1.7e-11 43.8 6.1 9.5e-07 28.6 0.2 6.0 3 3 3 6 6 6 3 FNIP Repeat FNIP PF05725.7 EGC31327.1 - 0.0059 16.5 1.1 0.2 11.6 0.8 2.3 1 1 0 1 1 1 1 FNIP Repeat DUF3430 PF11912.3 EGC31329.1 - 5.4e-21 75.4 29.1 5.4e-21 75.4 20.2 1.7 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) BTB PF00651.26 EGC31329.1 - 0.053 13.5 0.3 0.081 12.9 0.2 1.3 1 0 0 1 1 1 0 BTB/POZ domain LRR_4 PF12799.2 EGC31331.1 - 1.1e-44 149.3 85.1 2e-09 36.8 3.1 9.8 4 3 6 10 10 10 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC31331.1 - 1.4e-29 101.5 67.3 7.3e-09 35.2 3.2 7.9 3 3 5 8 8 8 8 Leucine rich repeat LRR_1 PF00560.28 EGC31331.1 - 2.5e-26 87.6 67.2 0.0057 16.5 0.1 16.1 16 0 0 16 16 16 11 Leucine Rich Repeat LRR_6 PF13516.1 EGC31331.1 - 8.6e-16 56.1 60.0 0.89 9.8 0.1 15.2 15 1 1 16 16 16 10 Leucine Rich repeat LRR_7 PF13504.1 EGC31331.1 - 1.8e-15 54.3 56.3 0.24 11.7 0.1 16.0 16 0 0 16 16 16 6 Leucine rich repeat LRR_2 PF07723.8 EGC31331.1 - 1.4 9.5 6.1 35 5.1 0.1 5.3 6 0 0 6 6 6 0 Leucine Rich Repeat FNIP PF05725.7 EGC31332.1 - 9.5e-20 70.2 7.1 6.2e-10 38.8 0.0 2.8 2 1 1 3 3 3 3 FNIP Repeat LRR_6 PF13516.1 EGC31332.1 - 0.087 12.9 4.4 5.7 7.3 0.1 3.6 2 2 1 3 3 3 0 Leucine Rich repeat DUF2951 PF11166.3 EGC31333.1 - 0.35 10.7 5.0 0.39 10.5 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) ABC-3 PF00950.12 EGC31339.1 - 0.093 12.0 0.6 0.082 12.1 0.4 1.0 1 0 0 1 1 1 0 ABC 3 transport family CENP-R PF06729.7 EGC31340.1 - 0.064 12.9 6.2 0.11 12.1 1.6 2.1 1 1 1 2 2 2 0 Kinetochore component, CENP-R DICT PF10069.4 EGC31341.1 - 0.023 14.2 0.1 0.67 9.4 0.0 2.3 2 0 0 2 2 2 0 Sensory domain found in DIguanylate Cyclases & Two-component systems HABP4_PAI-RBP1 PF04774.10 EGC31341.1 - 0.09 13.2 11.1 1.9 9.0 0.0 3.2 1 1 2 3 3 3 0 Hyaluronan / mRNA binding family zf-RING_2 PF13639.1 EGC31342.1 - 3e-16 58.9 6.7 3.3e-16 58.8 4.7 1.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC31342.1 - 1.2e-09 38.0 7.0 1.4e-09 37.8 4.8 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31342.1 - 4.3e-09 36.3 7.9 1.1e-08 35.0 5.5 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC31342.1 - 6.6e-08 32.1 6.1 7.7e-08 31.9 4.2 1.1 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC31342.1 - 4e-07 29.5 7.3 4.9e-07 29.2 5.1 1.1 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31342.1 - 6.4e-07 28.9 4.4 8e-07 28.6 3.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) RINGv PF12906.2 EGC31342.1 - 7.6e-05 22.6 6.5 0.0001 22.2 4.5 1.1 1 0 0 1 1 1 1 RING-variant domain zf-Apc11 PF12861.2 EGC31342.1 - 8.9e-05 22.2 4.5 0.00014 21.6 3.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGC31342.1 - 0.00033 20.5 8.2 0.0024 17.7 5.7 2.1 1 1 0 1 1 1 1 FANCL C-terminal domain zf-RING_UBOX PF13445.1 EGC31342.1 - 0.00075 19.1 1.0 0.00075 19.1 0.7 1.5 1 1 1 2 2 2 1 RING-type zinc-finger Prok-RING_1 PF14446.1 EGC31342.1 - 0.00086 18.9 2.2 0.00086 18.9 1.5 2.0 1 1 1 2 2 2 1 Prokaryotic RING finger family 1 zf-Nse PF11789.3 EGC31342.1 - 0.0013 18.1 3.8 0.0016 17.9 2.6 1.1 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGC31342.1 - 0.0067 16.1 2.7 0.013 15.2 1.8 1.5 1 1 0 1 1 1 1 zf-RING of BARD1-type protein zf-P11 PF03854.9 EGC31342.1 - 0.0089 15.4 1.8 0.0089 15.4 1.3 1.9 1 1 1 2 2 2 1 P-11 zinc finger zf-RING_4 PF14570.1 EGC31342.1 - 0.021 14.4 4.0 0.049 13.2 2.7 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGC31342.1 - 0.024 14.3 2.4 0.029 14.1 1.6 1.1 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) Rad50_zn_hook PF04423.9 EGC31342.1 - 0.045 13.2 1.3 0.062 12.7 0.0 1.8 2 1 0 2 2 2 0 Rad50 zinc hook motif UPF0547 PF10571.4 EGC31342.1 - 0.075 12.7 0.1 0.075 12.7 0.1 2.4 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-met2 PF12907.2 EGC31342.1 - 0.076 13.0 2.2 0.24 11.3 0.1 2.2 2 1 0 2 2 2 0 Zinc-binding zf-C3HC4_4 PF15227.1 EGC31342.1 - 0.078 12.8 5.5 0.25 11.2 3.9 1.8 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Vps39_2 PF10367.4 EGC31342.1 - 0.35 11.0 3.7 3.6 7.8 0.7 2.0 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 OrfB_Zn_ribbon PF07282.6 EGC31342.1 - 0.39 10.4 4.4 0.44 10.2 0.3 2.0 1 1 1 2 2 2 0 Putative transposase DNA-binding domain DUF1272 PF06906.6 EGC31342.1 - 0.41 10.5 3.0 0.52 10.2 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PHD PF00628.24 EGC31342.1 - 0.51 10.0 7.7 1.2 8.8 5.3 1.7 1 1 0 1 1 1 0 PHD-finger DUF4206 PF13901.1 EGC31342.1 - 0.55 9.7 5.1 0.72 9.3 3.5 1.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4206) zf-RING-like PF08746.6 EGC31342.1 - 1 9.4 7.0 3.6 7.6 4.8 1.9 1 1 0 1 1 1 0 RING-like domain zf-RING_3 PF14369.1 EGC31342.1 - 1 9.4 4.6 14 5.7 0.1 2.4 2 1 0 2 2 2 0 zinc-finger zf-DHHC PF01529.15 EGC31343.1 - 3.6e-41 140.4 6.8 3.6e-41 140.4 4.7 2.4 2 2 1 3 3 3 1 DHHC palmitoyltransferase Lectin_N PF03954.9 EGC31343.1 - 0.21 10.9 2.0 0.3 10.4 0.0 2.0 2 0 0 2 2 2 0 Hepatic lectin, N-terminal domain DUF3279 PF11682.3 EGC31343.1 - 0.25 10.8 6.1 0.43 10.1 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3279) SNAP PF14938.1 EGC31344.1 - 8.9e-111 369.5 14.7 1e-110 369.3 10.2 1.0 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGC31344.1 - 3.4e-12 46.1 13.0 4.6e-06 26.4 2.1 3.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31344.1 - 5e-07 29.2 15.5 0.0016 18.0 0.8 3.4 2 2 1 3 3 3 3 TPR repeat TPR_16 PF13432.1 EGC31344.1 - 4e-06 27.3 10.1 0.024 15.2 1.4 3.9 1 1 3 4 4 4 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31344.1 - 2.3e-05 23.8 12.8 0.053 13.3 0.2 5.3 4 2 1 5 5 5 2 Tetratricopeptide repeat Spatacsin_C PF14649.1 EGC31344.1 - 5.1e-05 22.2 4.8 0.0019 17.1 0.3 2.9 1 1 1 3 3 3 1 Spatacsin C-terminus TPR_1 PF00515.23 EGC31344.1 - 7.1e-05 22.2 19.0 0.41 10.3 0.6 5.8 5 0 0 5 5 5 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC31344.1 - 9.9e-05 22.4 13.7 0.0043 17.1 0.5 3.5 2 2 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 RPN7 PF10602.4 EGC31344.1 - 0.0001 21.7 3.4 0.00027 20.3 0.8 2.3 1 1 1 2 2 2 1 26S proteasome subunit RPN7 TPR_2 PF07719.12 EGC31344.1 - 0.00015 21.4 25.4 0.24 11.3 0.1 6.4 6 1 1 7 7 7 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31344.1 - 0.0002 21.6 9.3 0.11 12.7 0.0 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31344.1 - 0.00031 20.9 18.7 0.95 10.0 0.2 6.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31344.1 - 0.00031 21.1 7.4 1 10.1 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGC31344.1 - 0.023 13.9 0.2 0.56 9.4 0.0 2.6 2 0 0 2 2 2 0 SHNi-TPR TPR_8 PF13181.1 EGC31344.1 - 0.034 13.9 1.1 0.034 13.9 0.8 5.8 7 2 0 7 7 5 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31344.1 - 0.11 12.4 2.8 5.9 6.9 0.1 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGC31344.1 - 0.32 10.9 17.2 2.1 8.2 0.4 5.3 3 1 2 5 5 5 0 MIT (microtubule interacting and transport) domain Foie-gras_1 PF11817.3 EGC31344.1 - 0.63 9.4 5.4 2.3 7.6 3.7 2.1 1 1 0 1 1 1 0 Foie gras liver health family 1 Actin PF00022.14 EGC31345.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC31345.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DnaJ PF00226.26 EGC31346.1 - 1.9e-12 46.7 0.1 3.2e-12 46.0 0.1 1.3 1 0 0 1 1 1 1 DnaJ domain Pam16 PF03656.8 EGC31346.1 - 2.9e-10 40.0 0.1 3.2e-10 39.8 0.1 1.0 1 0 0 1 1 1 1 Pam16 RPT PF13446.1 EGC31346.1 - 0.01 15.2 0.0 0.036 13.4 0.0 1.9 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF3568 PF12092.3 EGC31346.1 - 0.08 12.6 0.1 0.1 12.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3568) Peptidase_C2 PF00648.16 EGC31346.1 - 0.13 11.2 0.0 0.15 11.0 0.0 1.1 1 0 0 1 1 1 0 Calpain family cysteine protease zf-H2C2_5 PF13909.1 EGC31347.1 - 0.0035 17.4 1.1 0.011 15.8 0.7 2.0 1 0 0 1 1 1 1 C2H2-type zinc-finger domain zf-C2H2_2 PF12756.2 EGC31347.1 - 0.022 14.8 1.0 0.022 14.8 0.7 2.3 2 0 0 2 2 2 0 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGC31347.1 - 0.038 14.3 0.5 0.038 14.3 0.4 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF4217 PF13959.1 EGC31347.1 - 0.11 12.0 0.1 0.26 10.8 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) zf-C2H2 PF00096.21 EGC31347.1 - 0.11 12.8 0.8 0.11 12.8 0.5 2.8 3 0 0 3 3 3 0 Zinc finger, C2H2 type DUF3505 PF12013.3 EGC31347.1 - 0.29 11.3 7.9 0.089 13.0 0.6 2.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3505) CRAL_TRIO_2 PF13716.1 EGC31348.1 - 6.9e-24 84.4 4.2 2.8e-23 82.4 2.7 2.1 2 0 0 2 2 2 1 Divergent CRAL/TRIO domain Macro PF01661.16 EGC31348.1 - 9.9e-16 57.7 0.2 2.1e-15 56.6 0.0 1.7 2 0 0 2 2 2 1 Macro domain CRAL_TRIO PF00650.15 EGC31348.1 - 2.1e-09 37.0 0.5 6.8e-09 35.4 0.1 2.0 3 0 0 3 3 3 1 CRAL/TRIO domain 4HBT PF03061.17 EGC31349.1 - 1.4e-07 31.5 0.0 2.2e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF1390 PF07150.6 EGC31349.1 - 0.59 9.4 11.6 1.2 8.4 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) JAB PF01398.16 EGC31350.1 - 9.6e-32 109.1 0.1 1.6e-31 108.3 0.1 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGC31350.1 - 1e-06 28.2 0.0 1.6e-06 27.5 0.0 1.3 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain UPF0172 PF03665.8 EGC31350.1 - 0.00045 19.7 0.8 0.00098 18.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0172) GBP_repeat PF02526.9 EGC31350.1 - 0.12 11.7 0.1 0.24 10.7 0.0 1.4 1 0 0 1 1 1 0 Glycophorin-binding protein CK_II_beta PF01214.13 EGC31351.1 - 5.4e-77 257.4 0.0 5.4e-77 257.4 0.0 1.7 2 0 0 2 2 2 1 Casein kinase II regulatory subunit zf-TFIIB PF13453.1 EGC31351.1 - 0.082 12.1 0.8 0.13 11.4 0.0 1.7 2 0 0 2 2 2 0 Transcription factor zinc-finger Adap_comp_sub PF00928.16 EGC31352.1 - 1e-27 96.9 0.3 1.7e-27 96.1 0.2 1.3 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Kinesin PF00225.18 EGC31353.1 - 9.7e-102 340.0 7.4 1.1e-101 339.8 5.1 1.0 1 0 0 1 1 1 1 Kinesin motor domain Urm1 PF09138.6 EGC31354.1 - 1.9e-36 124.0 0.3 2.1e-36 123.9 0.2 1.0 1 0 0 1 1 1 1 Urm1 (Ubiquitin related modifier) ThiS PF02597.15 EGC31354.1 - 0.03 14.7 0.0 0.036 14.5 0.0 1.2 1 0 0 1 1 1 0 ThiS family Peptidase_C54 PF03416.14 EGC31355.1 - 2.1e-90 302.6 0.1 4.8e-90 301.4 0.1 1.6 1 1 0 1 1 1 1 Peptidase family C54 Peptidase_C78 PF07910.8 EGC31355.1 - 0.0017 17.5 0.0 0.0046 16.1 0.0 1.7 1 0 0 1 1 1 1 Peptidase family C78 Rhodanese PF00581.15 EGC31356.1 - 8.7e-10 38.9 0.0 4e-09 36.8 0.0 2.3 1 0 0 1 1 1 1 Rhodanese-like domain UPF0014 PF03649.8 EGC31359.1 - 0.035 13.2 0.0 0.11 11.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0014) Tox-MPTase5 PF15641.1 EGC31359.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 MOR2-PAG1_N PF14222.1 EGC31359.1 - 0.61 8.6 3.5 0.74 8.4 2.4 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal FNIP PF05725.7 EGC31360.1 - 3.1e-178 577.5 36.5 5.7e-15 54.9 0.0 14.3 7 2 7 16 16 16 16 FNIP Repeat LSPR PF06049.7 EGC31360.1 - 0.01 15.0 1.2 31 4.6 0.0 5.3 4 0 0 4 4 4 0 Coagulation Factor V LSPD Repeat Bromodomain PF00439.20 EGC31361.1 - 9.6e-07 28.6 0.5 3.1e-06 26.9 0.3 1.9 1 1 0 1 1 1 1 Bromodomain PHD PF00628.24 EGC31361.1 - 0.00019 21.0 4.6 0.00019 21.0 3.2 3.1 2 0 0 2 2 2 1 PHD-finger ECH PF00378.15 EGC31362.1 - 4.9e-57 192.8 0.1 5.7e-57 192.6 0.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGC31362.1 - 3.5e-07 30.3 0.1 6.8e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region DUF3128 PF11326.3 EGC31363.1 - 0.082 13.0 0.0 0.63 10.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3128) SpoU_methylase PF00588.14 EGC31364.1 - 8e-27 93.8 0.2 1.5e-26 92.9 0.1 1.5 1 0 0 1 1 1 1 SpoU rRNA Methylase family Baculo_LEF5 PF04838.7 EGC31364.1 - 0.0098 15.6 1.2 0.91 9.2 0.2 2.5 2 0 0 2 2 2 2 Baculoviridae late expression factor 5 PrkA PF06798.7 EGC31364.1 - 0.049 12.9 0.2 0.33 10.1 0.0 2.2 1 1 1 2 2 2 0 PrkA serine protein kinase C-terminal domain BRCT PF00533.21 EGC31365.1 - 3.3e-13 49.5 3.6 4.8e-13 49.0 1.3 2.2 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC31365.1 - 0.012 15.4 0.1 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 twin BRCT domain 3H PF02829.9 EGC31365.1 - 0.061 13.3 2.0 2.1 8.3 0.2 2.9 2 0 0 2 2 2 0 3H domain bZIP_1 PF00170.16 EGC31365.1 - 1.3 9.0 13.0 0.96 9.4 0.3 4.2 2 1 1 3 3 3 0 bZIP transcription factor DUF2681 PF10883.3 EGC31365.1 - 6.9 6.9 10.9 1.2 9.3 2.8 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DivIC PF04977.10 EGC31365.1 - 7 6.2 16.0 5.8 6.4 0.2 3.9 2 1 1 3 3 3 0 Septum formation initiator UCH PF00443.24 EGC31366.1 - 7e-52 176.1 1.8 8.1e-52 175.9 0.7 1.4 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC31366.1 - 7.8e-28 97.7 0.7 7.8e-28 97.7 0.5 1.5 2 0 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGC31366.1 - 0.76 9.0 4.5 8.5 5.5 1.9 2.9 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase EGF_2 PF07974.8 EGC31369.1 - 5.6e-40 135.1 229.1 6.5e-05 23.0 9.4 12.7 10 2 2 12 12 12 12 EGF-like domain Toxin_2 PF00451.14 EGC31369.1 - 0.0013 18.7 9.2 0.0013 18.7 6.4 11.0 12 0 0 12 12 12 1 Scorpion short toxin, BmKK2 Herpes_UL33 PF03581.8 EGC31370.1 - 0.013 15.4 0.2 0.014 15.3 0.1 1.2 1 0 0 1 1 1 0 Herpesvirus UL33-like protein LIM_bind PF01803.11 EGC31370.1 - 0.5 9.4 3.9 0.54 9.3 2.7 1.0 1 0 0 1 1 1 0 LIM-domain binding protein COX4 PF02936.9 EGC31371.1 - 0.033 13.9 0.0 0.04 13.6 0.0 1.1 1 0 0 1 1 1 0 Cytochrome c oxidase subunit IV Cation_efflux PF01545.16 EGC31372.1 - 1.1e-67 228.1 0.7 1.4e-67 227.8 0.5 1.0 1 0 0 1 1 1 1 Cation efflux family NicO PF03824.11 EGC31372.1 - 0.0064 15.8 1.7 0.0064 15.8 1.2 1.9 2 0 0 2 2 2 1 High-affinity nickel-transport protein Zip PF02535.17 EGC31372.1 - 0.22 10.4 19.7 0.54 9.2 13.6 1.9 1 1 0 1 1 1 0 ZIP Zinc transporter CDC45 PF02724.9 EGC31372.1 - 0.34 8.8 3.2 0.47 8.4 2.3 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF3430 PF11912.3 EGC31373.1 - 2.8e-33 115.5 27.8 3.4e-33 115.2 19.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Kinesin PF00225.18 EGC31374.1 - 3e-55 187.2 6.7 3e-55 187.2 4.6 1.5 1 1 1 2 2 2 2 Kinesin motor domain ATP-sulfurylase PF01747.12 EGC31374.1 - 0.003 16.8 0.0 0.0045 16.3 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase TLP-20 PF06088.6 EGC31375.1 - 0.0016 18.1 0.1 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) Sporozoite_P67 PF05642.6 EGC31375.1 - 0.071 10.9 0.7 0.087 10.6 0.5 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ABC2_membrane_3 PF12698.2 EGC31376.1 - 1.2e-54 185.6 70.5 4.3e-28 98.3 23.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 EGC31376.1 - 1.6e-52 177.4 0.3 4.7e-25 88.4 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC31376.1 - 3e-06 26.6 0.0 0.57 9.3 0.0 3.9 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC31376.1 - 0.00012 21.5 2.9 0.014 14.9 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain SRP54 PF00448.17 EGC31376.1 - 0.0006 19.3 1.0 0.65 9.4 0.0 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EGC31376.1 - 0.0012 19.2 8.4 0.078 13.2 0.0 3.5 3 0 0 3 3 3 2 AAA domain SbcCD_C PF13558.1 EGC31376.1 - 0.0021 17.9 0.1 0.48 10.3 0.0 3.2 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EGC31376.1 - 0.012 15.8 0.0 0.69 10.1 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGC31376.1 - 0.016 14.5 0.3 1.4 8.2 0.1 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC31376.1 - 0.043 13.7 0.3 4.4 7.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC31376.1 - 0.085 12.0 1.4 1.6 7.8 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 EGC31376.1 - 0.21 10.7 46.0 1.1 8.4 8.8 4.5 4 0 0 4 4 4 0 ABC-2 type transporter EF1G PF00647.14 EGC31377.1 - 6.4e-38 128.7 0.0 1.3e-37 127.7 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EGC31377.1 - 1.5e-12 47.5 0.0 1.5e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC31377.1 - 2.5e-11 43.3 2.1 3.6e-11 42.8 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC31377.1 - 3.8e-08 33.1 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC31377.1 - 5.3e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC31377.1 - 1.3e-06 28.7 0.0 6.6e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC31377.1 - 9.3e-06 25.4 0.0 2.1e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain EIID-AGA PF03613.9 EGC31377.1 - 0.082 11.8 0.0 0.12 11.3 0.0 1.1 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component RabGAP-TBC PF00566.13 EGC31378.1 - 2.8e-39 134.8 3.0 2.8e-39 134.8 2.1 2.6 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Pkinase PF00069.20 EGC31378.1 - 3.3e-33 114.9 0.4 3.3e-33 114.9 0.3 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31378.1 - 5.4e-16 58.4 0.0 1.1e-14 54.1 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase Rhodanese PF00581.15 EGC31378.1 - 0.00016 21.9 0.0 0.00049 20.4 0.0 1.8 1 0 0 1 1 1 1 Rhodanese-like domain Kinase-like PF14531.1 EGC31378.1 - 0.0028 16.6 0.0 0.0054 15.7 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3458 PF11940.3 EGC31378.1 - 0.011 14.5 0.2 0.02 13.7 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3458) Prismane PF03063.15 EGC31378.1 - 0.39 9.0 0.0 0.59 8.4 0.0 1.2 1 0 0 1 1 1 0 Prismane/CO dehydrogenase family Pet127 PF08634.5 EGC31379.1 - 7.9e-91 303.9 1.6 7.9e-91 303.9 1.1 2.2 2 1 0 2 2 2 1 Mitochondrial protein Pet127 RIO1 PF01163.17 EGC31380.1 - 1.9e-49 167.6 0.3 5.7e-49 166.0 0.2 1.8 1 0 0 1 1 1 1 RIO1 family Rio2_N PF09202.6 EGC31380.1 - 3.2e-32 110.4 0.3 7.4e-32 109.2 0.2 1.7 1 0 0 1 1 1 1 Rio2, N-terminal APH PF01636.18 EGC31380.1 - 5.8e-10 39.3 0.0 0.00051 19.8 0.0 2.6 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGC31380.1 - 1.9e-07 30.3 0.0 5.8e-06 25.5 0.0 2.4 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGC31380.1 - 0.0058 15.8 0.1 0.0058 15.8 0.1 2.0 2 0 0 2 2 2 1 Protein kinase domain Kinase-like PF14531.1 EGC31380.1 - 0.043 12.7 0.0 0.42 9.5 0.0 2.1 2 0 0 2 2 2 0 Kinase-like Zip PF02535.17 EGC31380.1 - 0.36 9.7 5.5 0.59 9.0 3.8 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter CobT PF06213.7 EGC31380.1 - 2.7 7.0 38.0 0.071 12.2 21.9 1.5 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT F-box-like PF12937.2 EGC31381.1 - 0.11 12.2 0.0 0.32 10.7 0.0 1.9 1 0 0 1 1 1 0 F-box-like Mucin PF01456.12 EGC31383.1 - 0.34 10.6 14.5 0.57 9.9 10.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein EI24 PF07264.6 EGC31384.1 - 0.003 17.0 5.6 0.003 17.0 3.9 1.9 2 1 1 3 3 3 2 Etoposide-induced protein 2.4 (EI24) LrgA PF03788.9 EGC31384.1 - 0.052 13.2 1.5 0.15 11.7 1.1 1.6 1 1 1 2 2 2 0 LrgA family Pkinase PF00069.20 EGC31385.1 - 5.7e-73 245.2 0.0 8.5e-73 244.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31385.1 - 2e-56 190.9 0.0 3.6e-56 190.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC31385.1 - 0.00092 18.2 0.2 0.0019 17.1 0.1 1.5 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGC31385.1 - 0.0076 15.6 0.1 0.017 14.4 0.0 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL BSD PF03909.12 EGC31385.1 - 0.0096 15.6 0.5 0.026 14.2 0.3 1.7 1 0 0 1 1 1 1 BSD domain RIO1 PF01163.17 EGC31385.1 - 0.013 14.8 0.1 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGC31385.1 - 0.018 14.7 0.0 5.6 6.6 0.0 2.5 2 1 1 3 3 3 0 Phosphotransferase enzyme family DUF29 PF01724.11 EGC31385.1 - 0.053 13.3 0.9 0.12 12.2 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function DUF29 Kdo PF06293.9 EGC31385.1 - 0.083 11.9 0.0 0.15 11.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF904 PF06005.7 EGC31385.1 - 0.61 10.4 5.2 1.9 8.8 3.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF904) ATG16 PF08614.6 EGC31385.1 - 7.3 6.3 9.9 0.7 9.6 1.9 2.2 1 1 1 2 2 2 0 Autophagy protein 16 (ATG16) Peptidase_M41 PF01434.13 EGC31386.1 - 9e-74 247.5 0.1 1.2e-73 247.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGC31386.1 - 2.3e-44 150.7 0.0 7.6e-44 149.1 0.0 1.9 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC31386.1 - 2.4e-05 25.1 0.3 0.001 19.9 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_5 PF07728.9 EGC31386.1 - 0.00016 21.3 0.5 0.0023 17.6 0.0 2.9 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGC31386.1 - 0.0019 17.2 0.0 0.0066 15.5 0.0 1.9 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC31386.1 - 0.0053 16.8 0.4 0.18 11.9 0.1 3.0 2 1 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGC31386.1 - 0.012 15.5 2.0 0.16 11.9 0.0 3.0 3 1 1 4 4 4 0 AAA ATPase domain AAA_19 PF13245.1 EGC31386.1 - 0.013 15.1 1.3 0.034 13.8 0.9 1.6 1 0 0 1 1 1 0 Part of AAA domain AAA_25 PF13481.1 EGC31386.1 - 0.02 14.3 0.5 0.086 12.2 0.1 2.2 1 1 1 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGC31386.1 - 0.02 14.2 0.1 0.041 13.2 0.1 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein TIP49 PF06068.8 EGC31386.1 - 0.029 13.1 0.1 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_2 PF07724.9 EGC31386.1 - 0.033 14.0 0.3 0.26 11.1 0.0 2.4 2 1 0 2 2 2 0 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EGC31386.1 - 0.038 14.2 0.3 0.27 11.5 0.0 2.5 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGC31386.1 - 0.044 12.8 0.3 0.18 10.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin Mg_chelatase PF01078.16 EGC31386.1 - 0.054 12.6 0.1 0.11 11.6 0.1 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_28 PF13521.1 EGC31386.1 - 0.14 12.1 0.1 1.3 8.9 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC31386.1 - 0.15 11.8 0.0 0.33 10.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain Amidohydro_2 PF04909.9 EGC31387.1 - 4e-50 170.8 0.0 4.5e-50 170.7 0.0 1.0 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2_N PF07582.7 EGC31387.1 - 0.15 11.6 0.1 0.33 10.5 0.1 1.5 1 0 0 1 1 1 0 AP endonuclease family 2 C terminus Peptidase_M8 PF01457.11 EGC31388.1 - 1.5e-81 274.3 0.1 2.1e-81 273.8 0.1 1.2 1 0 0 1 1 1 1 Leishmanolysin TIG PF01833.19 EGC31388.1 - 1.7e-07 31.1 2.1 8.5e-07 28.8 1.5 2.3 1 0 0 1 1 1 1 IPT/TIG domain Peptidase_M10 PF00413.19 EGC31388.1 - 0.0085 15.8 0.1 0.017 14.8 0.0 1.7 1 1 0 1 1 1 1 Matrixin Tetraspannin PF00335.15 EGC31388.1 - 7.1 5.8 16.2 0.22 10.7 0.2 2.8 3 0 0 3 3 3 0 Tetraspanin family RRM_5 PF13893.1 EGC31389.1 - 3.6e-40 135.5 4.9 1.2e-13 50.7 0.1 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31389.1 - 9.1e-34 115.2 0.5 4.1e-09 36.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC31389.1 - 4.2e-31 106.4 0.5 9.8e-08 31.5 0.1 4.8 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Cpn60_TCP1 PF00118.19 EGC31390.1 - 1.4e-96 324.0 8.9 1.9e-96 323.6 6.2 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ribosomal_L10 PF00466.15 EGC31391.1 - 7.2e-20 70.7 1.5 1.9e-19 69.4 1.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L10 Ribosomal_60s PF00428.14 EGC31391.1 - 4.3e-16 59.0 10.7 4.5e-16 59.0 6.3 2.0 2 0 0 2 2 2 1 60s Acidic ribosomal protein PfkB PF00294.19 EGC31394.1 - 8.7e-10 38.2 0.0 1.2e-09 37.7 0.0 1.2 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Mob_Pre PF01076.14 EGC31394.1 - 0.14 11.7 0.0 0.18 11.4 0.0 1.1 1 0 0 1 1 1 0 Plasmid recombination enzyme HNH_3 PF13392.1 EGC31396.1 - 7.4e-11 41.2 2.7 1.7e-10 40.0 1.9 1.7 1 0 0 1 1 1 1 HNH endonuclease zf-CCHC_5 PF14787.1 EGC31396.1 - 2.3e-07 30.1 0.5 1.3e-06 27.7 0.2 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGC31396.1 - 0.00052 19.8 1.9 0.00086 19.1 1.3 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC31396.1 - 0.016 14.8 0.7 0.035 13.7 0.5 1.5 1 0 0 1 1 1 0 Zinc knuckle AHH PF14412.1 EGC31396.1 - 0.53 10.3 4.7 18 5.3 0.8 2.8 1 1 2 3 3 3 0 A nuclease family of the HNH/ENDO VII superfamily with conserved AHH HNH PF01844.18 EGC31396.1 - 8.8 6.2 8.4 0.49 10.2 1.5 2.0 2 0 0 2 2 2 0 HNH endonuclease PfkB PF00294.19 EGC31397.1 - 2.4e-14 53.1 0.0 1.5e-13 50.5 0.0 2.3 1 1 0 1 1 1 1 pfkB family carbohydrate kinase Mob_Pre PF01076.14 EGC31397.1 - 0.0099 15.5 0.1 0.016 14.8 0.1 1.3 1 0 0 1 1 1 1 Plasmid recombination enzyme Ras PF00071.17 EGC31398.1 - 2.8e-14 52.8 1.0 3.7e-14 52.4 0.6 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC31398.1 - 7.3e-13 49.0 0.3 1.2e-12 48.4 0.2 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC31398.1 - 0.00042 20.2 0.3 0.00069 19.5 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC31398.1 - 0.0048 16.3 0.8 0.093 12.1 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_14 PF13173.1 EGC31398.1 - 0.58 10.0 4.1 6.6 6.6 2.8 2.5 1 1 0 1 1 1 0 AAA domain DJ-1_PfpI_N PF13587.1 EGC31399.1 - 6.4e-18 63.9 0.1 1.1e-17 63.2 0.0 1.4 1 0 0 1 1 1 1 N-terminal domain of DJ-1_PfpI family DJ-1_PfpI PF01965.19 EGC31399.1 - 8.9e-18 64.1 0.0 1.6e-17 63.3 0.0 1.4 1 1 0 1 1 1 1 DJ-1/PfpI family Rcd1 PF04078.8 EGC31400.1 - 1.5e-120 400.9 0.1 1.8e-120 400.7 0.1 1.1 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like RAI16-like PF10257.4 EGC31401.1 - 6.4e-105 350.9 8.6 6.4e-105 350.9 5.9 1.8 2 0 0 2 2 2 1 Retinoic acid induced 16-like protein GatB_N PF02934.10 EGC31402.1 - 5.8e-105 350.2 0.0 8e-105 349.8 0.0 1.2 1 0 0 1 1 1 1 GatB/GatE catalytic domain GatB_Yqey PF02637.13 EGC31402.1 - 8.2e-36 122.9 0.0 1.8e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 GatB domain MMR_HSR1 PF01926.18 EGC31403.1 - 1.7e-11 44.0 0.4 2e-09 37.3 0.1 2.5 2 0 0 2 2 2 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC31403.1 - 0.00065 19.0 0.1 0.0024 17.1 0.0 1.9 2 0 0 2 2 2 1 Ferrous iron transport protein B IIGP PF05049.8 EGC31403.1 - 0.0029 16.4 0.0 0.0056 15.5 0.0 1.4 1 0 0 1 1 1 1 Interferon-inducible GTPase (IIGP) DUF258 PF03193.11 EGC31403.1 - 0.077 12.1 0.0 0.15 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 APC10 PF03256.11 EGC31404.1 - 3.8e-58 196.3 0.0 4.2e-58 196.1 0.0 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex, subunit 10 (APC10) PITH PF06201.8 EGC31404.1 - 0.033 13.9 0.4 0.81 9.4 0.3 2.2 1 1 0 1 1 1 0 PITH domain F5_F8_type_C PF00754.20 EGC31404.1 - 0.047 13.5 0.3 0.12 12.1 0.0 1.7 2 0 0 2 2 2 0 F5/8 type C domain JmjC PF02373.17 EGC31405.1 - 9.2e-39 132.2 0.6 4.5e-38 130.0 0.0 2.6 2 0 0 2 2 2 1 JmjC domain, hydroxylase ARID PF01388.16 EGC31405.1 - 3e-18 65.4 0.0 1e-17 63.7 0.0 2.0 1 0 0 1 1 1 1 ARID/BRIGHT DNA binding domain JmjN PF02375.12 EGC31405.1 - 5.3e-15 54.6 3.2 1.9e-14 52.8 2.2 2.1 1 0 0 1 1 1 1 jmjN domain zf-C5HC2 PF02928.11 EGC31405.1 - 0.00012 22.1 14.8 0.0023 17.9 0.2 2.7 2 0 0 2 2 2 2 C5HC2 zinc finger CDC45 PF02724.9 EGC31405.1 - 0.06 11.3 14.0 0.12 10.3 9.6 1.5 2 0 0 2 2 2 0 CDC45-like protein DUF4337 PF14235.1 EGC31405.1 - 1.9 8.3 7.7 4 7.2 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Peptidase_S13 PF02113.10 EGC31406.1 - 2.8e-69 233.7 0.0 3.8e-69 233.3 0.0 1.0 1 0 0 1 1 1 1 D-Ala-D-Ala carboxypeptidase 3 (S13) family Pentapeptide PF00805.17 EGC31407.1 - 6.2e-29 98.7 22.3 2.4e-11 42.6 2.6 4.2 2 1 2 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGC31407.1 - 1.2e-16 60.3 2.6 6.3e-08 32.3 0.3 2.5 1 1 1 2 2 2 2 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EGC31407.1 - 2.6e-14 53.2 0.1 6e-14 52.0 0.1 1.6 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide_3 PF13576.1 EGC31407.1 - 1.6e-13 50.3 0.6 2e-05 24.4 0.2 3.5 1 1 0 2 2 2 2 Pentapeptide repeats (9 copies) AKAP95 PF04988.7 EGC31407.1 - 0.076 12.7 0.0 0.15 11.8 0.0 1.4 1 0 0 1 1 1 0 A-kinase anchoring protein 95 (AKAP95) Hep_59 PF07052.6 EGC31409.1 - 1.9e-21 76.3 16.0 1.9e-21 76.3 11.1 2.9 2 2 2 4 4 4 1 Hepatocellular carcinoma-associated antigen 59 RRM_1 PF00076.17 EGC31410.1 - 3.2e-18 65.1 0.2 5.8e-10 38.6 0.0 2.3 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31410.1 - 1.7e-09 37.5 0.4 7.2e-05 22.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31410.1 - 0.036 13.9 0.1 0.43 10.4 0.0 2.1 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Vfa1 PF08432.5 EGC31410.1 - 0.074 13.0 11.5 0.1 12.5 8.0 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 U79_P34 PF03064.11 EGC31410.1 - 0.22 11.0 14.3 0.37 10.2 9.9 1.3 1 0 0 1 1 1 0 HSV U79 / HCMV P34 Glycoprotein_B PF00606.13 EGC31410.1 - 0.29 9.0 3.0 0.15 10.0 0.4 1.6 1 1 1 2 2 2 0 Herpesvirus Glycoprotein B DUF605 PF04652.11 EGC31410.1 - 0.54 9.5 21.6 0.71 9.2 14.9 1.1 1 0 0 1 1 1 0 Vta1 like Presenilin PF01080.12 EGC31410.1 - 0.65 8.7 8.9 0.99 8.1 6.2 1.2 1 0 0 1 1 1 0 Presenilin Hid1 PF12722.2 EGC31410.1 - 0.89 7.1 10.8 1.1 6.9 7.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EGC31410.1 - 1.2 7.5 15.1 1.5 7.2 10.4 1.0 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 CobT PF06213.7 EGC31410.1 - 9.8 5.2 16.2 17 4.4 11.2 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Tiny_TM_bacill PF09680.5 EGC31411.1 - 1.7 8.1 6.0 4.2 6.8 4.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (Tiny_TM_bacill) GCR1_C PF12550.3 EGC31413.1 - 0.087 12.7 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 Transcriptional activator of glycolytic enzymes Phage_BR0599 PF09356.5 EGC31414.1 - 0.051 13.7 0.0 0.067 13.3 0.0 1.2 1 0 0 1 1 1 0 Phage conserved hypothetical protein BR0599 RVT_1 PF00078.22 EGC31415.1 - 1.3e-05 24.6 0.0 1.5e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) DUF1091 PF06477.8 EGC31415.1 - 0.18 12.2 3.1 0.34 11.3 2.1 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1091) DUF1600 PF07667.6 EGC31415.1 - 2 8.5 9.6 2.7 8.1 6.7 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1600) RVT_1 PF00078.22 EGC31416.1 - 1.2e-06 28.0 0.0 1.5e-06 27.7 0.0 1.1 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) Pep3_Vps18 PF05131.9 EGC31418.1 - 6.7e-33 113.1 1.7 1.6e-32 111.9 0.3 2.3 2 0 0 2 2 2 1 Pep3/Vps18/deep orange family Clathrin PF00637.15 EGC31418.1 - 1.8e-13 50.3 5.5 1.8e-13 50.3 3.8 3.2 2 1 0 2 2 2 1 Region in Clathrin and VPS zf-RING_2 PF13639.1 EGC31418.1 - 2.2e-05 24.2 1.8 8.4e-05 22.3 1.2 2.0 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC31418.1 - 0.00013 21.6 1.8 0.00032 20.3 1.2 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC31418.1 - 0.015 15.3 1.7 0.05 13.6 1.2 1.9 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Vps39_2 PF10367.4 EGC31418.1 - 0.031 14.4 0.3 0.11 12.6 0.1 2.1 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 zf-Apc11 PF12861.2 EGC31418.1 - 0.052 13.3 0.1 0.13 12.0 0.1 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4 PF00097.20 EGC31418.1 - 0.11 12.1 1.5 0.29 10.8 1.0 1.7 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF2175 PF09943.4 EGC31418.1 - 0.15 12.1 0.0 0.15 12.1 0.0 2.8 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2175) Methyltransf_12 PF08242.7 EGC31418.1 - 0.93 10.0 4.2 7.8 7.0 0.1 3.1 2 0 0 2 2 2 0 Methyltransferase domain zf-ZPR1 PF03367.8 EGC31419.1 - 1.2e-101 336.5 2.1 2.7e-54 182.6 0.1 2.3 2 0 0 2 2 2 2 ZPR1 zinc-finger domain zf-DNL PF05180.7 EGC31419.1 - 0.0041 16.7 0.3 4.8 6.9 0.1 3.0 2 0 0 2 2 2 2 DNL zinc finger HypA PF01155.14 EGC31419.1 - 0.0052 16.4 1.9 0.054 13.1 0.1 2.5 2 0 0 2 2 2 1 Hydrogenase expression/synthesis hypA family SWI-SNF_Ssr4 PF08549.5 EGC31419.1 - 0.033 12.5 0.0 1.6 6.9 0.0 2.1 2 0 0 2 2 2 0 Fungal domain of unknown function (DUF1750) DUF1610 PF07754.6 EGC31419.1 - 0.12 12.5 6.2 1.1 9.4 1.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1610) UPF0547 PF10571.4 EGC31419.1 - 0.43 10.3 8.2 0.77 9.4 0.0 3.8 4 0 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-AN1 PF01428.11 EGC31419.1 - 1.6 8.6 6.9 14 5.6 0.0 3.6 4 0 0 4 4 4 0 AN1-like Zinc finger zf-H2C2_2 PF13465.1 EGC31419.1 - 1.8 8.9 9.2 28 5.2 0.1 4.0 4 0 0 4 4 4 0 Zinc-finger double domain zinc_ribbon_2 PF13240.1 EGC31419.1 - 3.2 7.3 10.2 18 4.9 0.1 4.0 4 0 0 4 4 4 0 zinc-ribbon domain Zn-ribbon_8 PF09723.5 EGC31419.1 - 6.8 6.7 8.4 26 4.8 0.1 3.6 4 0 0 4 4 4 0 Zinc ribbon domain zf-ribbon_3 PF13248.1 EGC31419.1 - 8.2 5.7 7.8 17 4.7 0.1 3.4 3 0 0 3 3 3 0 zinc-ribbon domain Peptidase_S28 PF05577.7 EGC31420.1 - 8.4e-98 327.7 8.3 9.6e-98 327.5 5.8 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EGC31420.1 - 7.3e-06 26.0 0.0 1.5e-05 24.9 0.0 1.5 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC31420.1 - 4.8e-05 23.1 0.0 0.00015 21.5 0.0 1.7 2 0 0 2 2 2 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC31420.1 - 0.00085 18.9 0.0 0.0013 18.3 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC31420.1 - 0.0048 16.1 0.0 0.02 14.1 0.0 1.9 2 0 0 2 2 2 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGC31420.1 - 0.02 14.3 0.1 0.062 12.7 0.0 1.7 2 0 0 2 2 2 0 X-Pro dipeptidyl-peptidase (S15 family) Sporozoite_P67 PF05642.6 EGC31421.1 - 0.0065 14.4 5.9 0.0087 13.9 4.1 1.2 1 0 0 1 1 1 1 Sporozoite P67 surface antigen DUF2457 PF10446.4 EGC31421.1 - 0.0072 15.0 10.6 0.01 14.6 7.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) RNase_H2_suC PF08615.6 EGC31421.1 - 0.01 15.6 1.1 0.11 12.3 0.7 2.1 2 0 0 2 2 2 0 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) Nucleoplasmin PF03066.10 EGC31421.1 - 0.11 12.0 8.0 0.17 11.3 5.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin CDC45 PF02724.9 EGC31421.1 - 0.25 9.3 8.4 0.39 8.6 5.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EGC31421.1 - 0.47 9.3 9.4 0.1 11.5 4.2 1.7 2 0 0 2 2 2 0 Translocon-associated protein (TRAP), alpha subunit Prothymosin PF03247.9 EGC31421.1 - 1.5 9.0 22.5 0.049 13.7 11.0 2.0 2 0 0 2 2 2 0 Prothymosin/parathymosin family Pox_Ag35 PF03286.9 EGC31421.1 - 1.7 8.1 21.9 0.11 11.9 11.1 1.9 2 1 0 2 2 2 0 Pox virus Ag35 surface protein YqaJ PF09588.5 EGC31422.1 - 1.5e-17 64.0 0.0 1.7e-17 63.8 0.0 1.0 1 0 0 1 1 1 1 YqaJ-like viral recombinase domain zf-CCHC PF00098.18 EGC31425.1 - 0.00068 19.4 1.5 0.0012 18.6 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGC31425.1 - 0.0097 15.3 0.4 0.02 14.3 0.3 1.5 1 0 0 1 1 1 1 Zinc knuckle 5_3_exonuc PF01367.15 EGC31425.1 - 0.25 11.5 2.8 15 5.8 0.5 3.5 3 0 0 3 3 3 0 5'-3' exonuclease, C-terminal SAM fold XRN_N PF03159.13 EGC31426.1 - 2.3e-45 154.8 0.0 2.5e-45 154.7 0.0 1.0 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus DUF1510 PF07423.6 EGC31427.1 - 0.31 10.3 8.0 2.6 7.3 3.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) DUF2201_N PF13203.1 EGC31427.1 - 0.32 10.1 4.1 0.58 9.2 2.8 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF605 PF04652.11 EGC31427.1 - 0.8 9.0 13.9 0.16 11.3 7.1 1.6 2 0 0 2 2 2 0 Vta1 like MGC-24 PF05283.6 EGC31427.1 - 1.2 8.8 12.5 0.029 14.1 3.8 1.8 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) DUF3827 PF12877.2 EGC31427.1 - 1.5 6.8 9.2 2.3 6.1 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) AMP-binding PF00501.23 EGC31428.1 - 1.7e-65 221.0 0.0 2.1e-65 220.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EGC31429.1 - 7.8e-13 47.5 0.0 1e-12 47.2 0.0 1.2 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC31429.1 - 0.12 13.3 0.0 0.3 12.0 0.0 1.7 1 1 0 1 1 1 0 AMP-binding enzyme C-terminal domain WD40 PF00400.27 EGC31430.1 - 3.8e-21 74.1 7.0 1.8e-06 27.5 0.0 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat Alpha_kinase PF02816.13 EGC31431.1 - 4.2e-57 192.8 0.1 9.1e-57 191.7 0.1 1.6 1 0 0 1 1 1 1 Alpha-kinase family WD40 PF00400.27 EGC31431.1 - 1.4e-41 138.9 17.1 4.8e-08 32.5 0.1 7.9 8 0 0 8 8 8 6 WD domain, G-beta repeat PhoU PF01895.14 EGC31431.1 - 0.09 13.2 0.7 0.22 11.9 0.2 1.8 2 0 0 2 2 2 0 PhoU domain bZIP_2 PF07716.10 EGC31431.1 - 1.1 9.0 4.8 2.1 8.2 3.3 1.4 1 0 0 1 1 1 0 Basic region leucine zipper RhoGEF PF00621.15 EGC31432.1 - 1.8e-37 128.9 0.6 1.8e-37 128.9 0.4 2.3 2 0 0 2 2 2 1 RhoGEF domain Arm PF00514.18 EGC31432.1 - 1.8e-16 59.2 7.5 0.00033 20.3 0.0 7.8 7 0 0 7 7 7 4 Armadillo/beta-catenin-like repeat PH PF00169.24 EGC31432.1 - 2.1e-08 34.3 0.9 1e-07 32.1 0.6 2.2 1 0 0 1 1 1 1 PH domain KAP PF05804.7 EGC31432.1 - 2.7e-08 32.2 14.9 5.3e-08 31.2 10.3 1.4 1 0 0 1 1 1 1 Kinesin-associated protein (KAP) HEAT_2 PF13646.1 EGC31432.1 - 0.0004 20.5 0.3 0.74 10.1 0.0 4.0 2 1 1 3 3 3 1 HEAT repeats HEAT PF02985.17 EGC31432.1 - 0.11 12.6 0.4 6.5 7.1 0.0 3.8 4 0 0 4 4 4 0 HEAT repeat MFS_2 PF13347.1 EGC31433.1 - 2.8e-100 335.7 26.2 3.3e-100 335.4 18.2 1.0 1 0 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EGC31433.1 - 6.4e-23 81.0 47.9 1.3e-16 60.3 19.1 2.3 1 1 1 2 2 2 2 Major Facilitator Superfamily ATG22 PF11700.3 EGC31433.1 - 7.3e-14 51.1 24.0 1.2e-13 50.4 16.6 1.3 1 1 0 1 1 1 1 Vacuole effluxer Atg22 like TRIQK PF15168.1 EGC31433.1 - 2.9 7.8 0.0 2.9 7.8 0.0 3.5 4 1 1 5 5 5 0 Triple QxxK/R motif-containing protein family DUF1296 PF06972.6 EGC31434.1 - 0.073 13.0 0.1 0.093 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1296) Tweety PF04906.8 EGC31435.1 - 0.0006 18.3 0.8 0.023 13.1 1.0 2.1 2 0 0 2 2 2 1 Tweety DUF2753 PF10952.3 EGC31435.1 - 0.012 15.6 0.0 0.031 14.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2753) Band_3_cyto PF07565.8 EGC31435.1 - 0.5 9.8 6.2 0.76 9.2 4.3 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Exonuc_VII_L PF02601.10 EGC31435.1 - 3.8 6.6 13.8 6.2 5.9 9.6 1.3 1 0 0 1 1 1 0 Exonuclease VII, large subunit SapB_2 PF03489.12 EGC31436.1 - 1.3e-22 79.4 11.8 6.4e-14 51.6 1.1 3.0 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC31436.1 - 8.2e-16 57.4 8.3 1.4e-09 37.5 3.1 3.7 5 0 0 5 5 5 2 Saposin-like type B, region 1 CZB PF13682.1 EGC31436.1 - 0.1 12.8 0.0 0.25 11.5 0.0 1.6 1 0 0 1 1 1 0 Chemoreceptor zinc-binding domain DIM PF08194.7 EGC31436.1 - 0.44 10.5 2.7 0.55 10.2 0.2 2.2 2 0 0 2 2 2 0 DIM protein DUF3456 PF11938.3 EGC31436.1 - 0.86 9.5 8.2 13 5.7 0.1 3.1 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP FA_desaturase PF00487.19 EGC31437.1 - 9.8e-42 143.1 9.7 1.6e-41 142.4 6.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGC31437.1 - 3.6e-23 81.1 0.0 6.8e-23 80.2 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain PRD PF00874.15 EGC31437.1 - 0.0053 16.8 0.0 0.026 14.6 0.0 2.2 1 0 0 1 1 1 1 PRD domain adh_short PF00106.20 EGC31438.1 - 4.3e-23 82.0 0.0 5.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC31438.1 - 6.8e-12 45.4 0.0 2.9e-08 33.5 0.0 2.1 2 0 0 2 2 2 2 KR domain adh_short_C2 PF13561.1 EGC31438.1 - 1.5e-10 41.2 0.1 2.6e-10 40.4 0.0 1.3 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EGC31438.1 - 3e-05 23.1 0.0 4.1e-05 22.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase F420_oxidored PF03807.12 EGC31438.1 - 0.00099 19.4 0.0 0.002 18.5 0.0 1.5 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent DXP_reductoisom PF02670.11 EGC31438.1 - 0.016 15.7 0.1 0.71 10.4 0.0 2.7 3 0 0 3 3 3 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase NAD_binding_10 PF13460.1 EGC31438.1 - 0.024 14.6 0.0 0.044 13.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Helicase_RecD PF05127.9 EGC31438.1 - 0.059 13.0 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 Helicase DUF4358 PF14270.1 EGC31438.1 - 0.16 11.8 2.5 0.21 11.4 0.3 2.2 3 0 0 3 3 3 0 Domain of unknown function (DUF4358) F5_F8_type_C PF00754.20 EGC31439.1 - 8.7e-25 87.0 0.4 8.7e-25 87.0 0.3 1.6 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC31439.1 - 1.1e-21 76.2 0.2 2.6e-21 75.0 0.1 1.6 1 0 0 1 1 1 1 H-type lectin domain ASCH PF04266.9 EGC31440.1 - 2.1e-15 56.9 0.0 2.4e-15 56.8 0.0 1.0 1 0 0 1 1 1 1 ASCH domain SLT PF01464.15 EGC31441.1 - 1.6e-07 30.8 0.0 3.2e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 EGC31441.1 - 0.0019 18.1 5.9 0.0072 16.3 4.1 1.8 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family DUF605 PF04652.11 EGC31441.1 - 2.1 7.6 26.1 3.1 7.0 18.1 1.3 1 0 0 1 1 1 0 Vta1 like Rad60-SLD PF11976.3 EGC31442.1 - 3.1e-19 68.4 3.1 5.8e-12 45.1 0.2 3.2 4 0 0 4 4 4 2 Ubiquitin-2 like Rad60 SUMO-like TPR_11 PF13414.1 EGC31443.1 - 3.1e-19 68.3 1.2 0.00017 21.2 0.0 4.4 4 0 0 4 4 4 4 TPR repeat TPR_2 PF07719.12 EGC31443.1 - 1e-12 46.9 0.0 0.0063 16.3 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC31443.1 - 3.3e-12 45.4 0.0 0.0082 15.7 0.0 5.8 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31443.1 - 1.5e-07 31.2 0.6 0.048 13.6 0.1 3.7 3 2 0 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31443.1 - 1.8e-07 30.4 0.3 0.73 9.7 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31443.1 - 7e-06 26.5 0.0 1.4 9.6 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31443.1 - 0.00025 20.8 0.0 0.49 10.2 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31443.1 - 0.00097 19.1 0.1 5.1 7.5 0.0 4.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31443.1 - 0.012 15.9 0.0 6.2 7.2 0.0 3.8 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1249 PF06853.7 EGC31443.1 - 0.091 12.4 3.3 10 5.8 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1249) DUF4539 PF15072.1 EGC31445.1 - 7.6e-24 83.2 0.0 1.4e-23 82.4 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4539) PAT1 PF09770.4 EGC31445.1 - 2 6.5 95.5 0.12 10.6 48.3 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 LRR_8 PF13855.1 EGC31446.1 - 1.1e-12 47.4 28.0 1.6e-05 24.5 0.6 6.3 2 1 4 7 7 7 6 Leucine rich repeat LRR_6 PF13516.1 EGC31446.1 - 9.7e-08 31.3 41.3 0.14 12.2 0.0 11.8 10 3 1 11 11 11 4 Leucine Rich repeat LRR_7 PF13504.1 EGC31446.1 - 1.9e-05 24.0 23.2 1.4 9.4 0.1 10.2 11 1 0 11 11 11 3 Leucine rich repeat LRR_1 PF00560.28 EGC31446.1 - 0.014 15.3 45.8 3 8.2 1.1 11.6 8 3 0 8 8 8 0 Leucine Rich Repeat STAS PF01740.16 EGC31446.1 - 0.015 14.7 0.1 2.2 7.7 0.0 2.9 3 0 0 3 3 3 0 STAS domain TPT PF03151.11 EGC31447.1 - 6.5e-21 74.5 40.1 1.4e-20 73.4 12.0 3.1 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGC31447.1 - 3.4e-13 49.7 39.7 3.3e-08 33.6 10.1 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EGC31447.1 - 1.3e-08 34.1 31.5 2.5e-08 33.2 21.7 1.5 1 1 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGC31447.1 - 0.00018 21.6 30.6 0.00054 20.1 4.5 3.4 2 2 1 3 3 3 2 Multidrug resistance efflux transporter 7TMR-DISM_7TM PF07695.6 EGC31447.1 - 0.53 9.9 49.6 0.039 13.6 15.7 2.5 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF2484 PF10658.4 EGC31447.1 - 3.8 7.6 7.3 8.1 6.6 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2484) zf-CCCH PF00642.19 EGC31448.1 - 3.8e-11 42.3 12.5 6.9e-07 28.7 1.1 2.4 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_1 PF00076.17 EGC31448.1 - 0.00092 18.7 0.1 0.016 14.8 0.1 2.2 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31448.1 - 0.056 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rhodanese PF00581.15 EGC31449.1 - 4.4e-13 49.5 0.0 6.7e-12 45.7 0.0 2.0 2 0 0 2 2 2 1 Rhodanese-like domain CENP-F_C_Rb_bdg PF10490.4 EGC31449.1 - 0.11 11.8 0.1 20 4.5 0.0 2.6 2 0 0 2 2 2 0 Rb-binding domain of kinetochore protein Cenp-F/LEK1 OPA3 PF07047.7 EGC31450.1 - 6.7e-35 119.7 0.5 7.8e-35 119.5 0.4 1.1 1 0 0 1 1 1 1 Optic atrophy 3 protein (OPA3) GSCFA PF08885.6 EGC31450.1 - 0.0095 15.5 0.1 0.011 15.3 0.1 1.0 1 0 0 1 1 1 1 GSCFA family YfbU PF03887.9 EGC31450.1 - 0.054 13.0 0.2 1 8.9 0.0 2.0 2 0 0 2 2 2 0 YfbU domain DUF2762 PF10960.3 EGC31450.1 - 0.13 11.9 1.2 0.47 10.1 0.9 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2762) RRF_GI PF12614.3 EGC31450.1 - 0.24 11.2 1.5 0.5 10.1 0.3 1.9 1 1 1 2 2 2 0 Ribosome recycling factor AMP-binding PF00501.23 EGC31451.1 - 3.2e-09 35.6 0.0 1.2e-06 27.2 0.0 2.1 2 0 0 2 2 2 2 AMP-binding enzyme Sel1 PF08238.7 EGC31452.1 - 3.7e-19 68.6 1.4 8.4e-08 32.6 0.2 5.1 5 0 0 5 5 5 3 Sel1 repeat OmdA PF13376.1 EGC31452.1 - 0.0082 15.7 2.5 0.026 14.1 0.1 2.8 3 0 0 3 3 3 1 Bacteriocin-protection, YdeI or OmpD-Associated TPR_2 PF07719.12 EGC31452.1 - 0.012 15.4 7.9 0.24 11.3 0.1 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31452.1 - 0.017 15.5 2.4 2.8 8.5 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC31452.1 - 0.017 15.2 3.6 0.94 9.6 0.0 3.7 3 1 0 3 3 3 0 Anaphase-promoting complex, cyclosome, subunit 3 SRI PF08236.6 EGC31452.1 - 0.02 14.8 4.9 0.65 9.9 0.0 2.5 2 0 0 2 2 2 0 SRI (Set2 Rpb1 interacting) domain MA3 PF02847.12 EGC31452.1 - 0.033 13.8 1.4 0.31 10.7 0.0 3.0 3 0 0 3 3 3 0 MA3 domain TPR_3 PF07720.7 EGC31452.1 - 0.064 13.0 0.6 0.064 13.0 0.4 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31452.1 - 1.4 8.6 4.4 4.1 7.1 0.1 3.7 3 2 1 4 4 4 0 TPR repeat TPR_1 PF00515.23 EGC31452.1 - 7 6.4 9.3 6.8 6.4 0.1 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat SNARE_assoc PF09335.6 EGC31453.1 - 2.6e-08 34.1 2.4 1e-07 32.2 0.0 3.0 2 1 2 4 4 4 1 SNARE associated Golgi protein MtrG PF04210.8 EGC31453.1 - 0.69 9.6 3.9 0.42 10.3 0.1 2.5 3 0 0 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G PRA1 PF03208.14 EGC31454.1 - 8e-26 90.2 6.3 8.8e-26 90.0 4.4 1.0 1 0 0 1 1 1 1 PRA1 family protein DUF4229 PF14012.1 EGC31454.1 - 0.065 13.1 0.3 0.065 13.1 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4229) DUF2207 PF09972.4 EGC31454.1 - 0.31 9.5 5.3 0.46 9.0 3.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) HEM4 PF02602.10 EGC31455.1 - 6.1e-25 87.8 0.0 9.6e-25 87.1 0.0 1.3 1 0 0 1 1 1 1 Uroporphyrinogen-III synthase HemD TPR_11 PF13414.1 EGC31455.1 - 2.1e-11 43.3 3.8 7.1e-05 22.3 0.0 2.8 2 0 0 2 2 2 2 TPR repeat TPR_16 PF13432.1 EGC31455.1 - 2.1e-11 44.1 1.9 7.9e-06 26.4 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31455.1 - 6.7e-11 41.4 2.5 0.0067 16.5 0.1 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31455.1 - 2.3e-10 40.6 5.6 0.00014 22.0 0.0 3.4 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31455.1 - 2.5e-08 33.8 0.7 0.1 13.2 0.0 4.2 1 1 3 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31455.1 - 1.9e-07 30.4 7.4 0.62 10.1 0.7 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31455.1 - 1e-06 28.6 8.4 0.0029 17.5 0.4 3.8 2 2 1 3 3 3 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31455.1 - 6e-06 25.6 7.8 1.7 8.6 0.3 5.2 3 1 1 4 4 4 2 Tetratricopeptide repeat SLS PF14611.1 EGC31455.1 - 0.0062 15.9 0.2 0.017 14.5 0.2 1.7 1 0 0 1 1 1 1 Mitochondrial inner-membrane-bound regulator TPR_7 PF13176.1 EGC31455.1 - 0.0083 15.8 0.5 0.52 10.2 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat PPR PF01535.15 EGC31455.1 - 0.052 13.5 0.0 1.4 9.0 0.0 2.9 2 0 0 2 2 2 0 PPR repeat DUF3366 PF11846.3 EGC31455.1 - 0.12 12.2 1.9 0.9 9.3 1.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3366) TPR_6 PF13174.1 EGC31455.1 - 0.29 11.6 4.1 8.5 7.0 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC31455.1 - 3.6 7.3 9.9 15 5.4 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat Cyclin_N PF00134.18 EGC31456.1 - 4.7e-14 52.0 1.8 1e-13 50.9 1.2 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain zf-HIT PF04438.11 EGC31457.1 - 2.4e-07 30.2 17.5 3.6e-07 29.6 12.2 1.3 1 0 0 1 1 1 1 HIT zinc finger CDC45 PF02724.9 EGC31457.1 - 9.7 4.0 10.9 13 3.7 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein HECT PF00632.20 EGC31458.1 - 1.2e-99 333.5 0.1 1.6e-99 333.0 0.1 1.2 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) LCM PF04072.9 EGC31459.1 - 2e-32 112.2 0.0 6.2e-32 110.6 0.0 1.8 2 0 0 2 2 2 1 Leucine carboxyl methyltransferase Med15 PF09606.5 EGC31459.1 - 0.96 7.5 24.2 1.6 6.8 16.8 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Activator_LAG-3 PF11498.3 EGC31459.1 - 1.4 7.5 28.5 3 6.5 19.7 1.5 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ras PF00071.17 EGC31461.1 - 4.6e-37 126.8 0.0 5.5e-37 126.6 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31461.1 - 1.9e-11 44.4 0.0 3.2e-11 43.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC31461.1 - 7.4e-05 22.0 0.0 9.8e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC31461.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.4 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region Septin PF00735.13 EGC31461.1 - 0.02 13.9 0.0 0.037 13.0 0.0 1.4 1 0 0 1 1 1 0 Septin MMR_HSR1 PF01926.18 EGC31461.1 - 0.11 12.4 0.0 0.18 11.7 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase Poty_PP PF08440.5 EGC31463.1 - 0.039 13.0 0.8 0.054 12.5 0.6 1.1 1 0 0 1 1 1 0 Potyviridae polyprotein SPAN-X PF07458.7 EGC31463.1 - 0.6 10.3 6.9 0.2 11.9 2.6 1.7 1 1 1 2 2 2 0 Sperm protein associated with nucleus, mapped to X chromosome adh_short PF00106.20 EGC31464.1 - 2.1e-20 73.2 0.0 2.6e-20 72.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC31464.1 - 4e-14 52.9 0.0 5.6e-14 52.4 0.0 1.2 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC31464.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC31464.1 - 0.0012 18.0 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC31464.1 - 0.0093 15.4 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC31464.1 - 0.033 14.2 0.0 0.044 13.7 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding RNA_pol_Rpc4 PF05132.9 EGC31467.1 - 0.075 13.0 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4195 PF13836.1 EGC31467.1 - 0.17 11.5 2.5 0.11 12.1 0.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4195) RasGAP PF00616.14 EGC31468.1 - 1.6e-10 40.9 4.4 1.6e-10 40.9 3.0 4.2 2 2 1 3 3 3 1 GTPase-activator protein for Ras-like GTPase PucR PF07905.6 EGC31468.1 - 0.047 13.2 0.0 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Purine catabolism regulatory protein-like family CLU PF13236.1 EGC31469.1 - 6.8e-45 153.2 0.0 2.9e-44 151.1 0.0 2.2 2 0 0 2 2 2 1 Clustered mitochondria TPR_12 PF13424.1 EGC31469.1 - 1.2e-33 114.9 3.9 3.8e-11 42.7 0.0 4.8 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31469.1 - 9.5e-14 50.8 0.0 0.025 14.5 0.0 6.2 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31469.1 - 1.8e-11 43.4 5.9 6.7e-06 25.6 0.3 4.3 2 1 3 5 5 5 4 TPR repeat TPR_2 PF07719.12 EGC31469.1 - 1.9e-08 33.5 0.9 0.011 15.5 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC31469.1 - 1.4e-07 30.7 6.3 0.01 15.4 0.2 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31469.1 - 9e-07 28.2 17.1 0.038 13.7 0.3 6.6 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31469.1 - 1.3e-06 27.7 0.4 0.044 13.5 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat eIF3_p135 PF12807.2 EGC31469.1 - 3.8e-05 23.6 0.2 3.8e-05 23.6 0.2 4.3 4 1 0 4 4 3 1 Translation initiation factor eIF3 subunit 135 TPR_16 PF13432.1 EGC31469.1 - 0.0071 16.9 0.0 0.038 14.6 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat NOA36 PF06524.7 EGC31469.1 - 4.2 6.5 15.7 11 5.2 10.9 1.6 1 0 0 1 1 1 0 NOA36 protein ADP_ribosyl_GH PF03747.9 EGC31470.1 - 4.8e-37 128.2 0.0 6.2e-37 127.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase STE2 PF02116.10 EGC31471.1 - 0.0064 15.5 0.5 0.0079 15.2 0.3 1.2 1 0 0 1 1 1 1 Fungal pheromone mating factor STE2 GPCR Oxidored_q5_N PF01059.12 EGC31471.1 - 0.017 14.9 1.5 0.022 14.6 1.1 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus PseudoU_synth_1 PF01416.15 EGC31472.1 - 1.2e-10 41.7 0.0 4.2e-09 36.7 0.0 2.9 2 0 0 2 2 2 1 tRNA pseudouridine synthase DDA1 PF10172.4 EGC31473.1 - 2.6e-07 30.3 1.5 3.2e-07 30.0 0.2 1.8 2 0 0 2 2 2 1 Det1 complexing ubiquitin ligase HNF-1_N PF04814.8 EGC31473.1 - 0.027 14.5 0.5 0.032 14.3 0.3 1.1 1 0 0 1 1 1 0 Hepatocyte nuclear factor 1 (HNF-1), N terminus Profilin PF00235.14 EGC31474.1 - 2.9e-16 59.6 0.5 4.2e-16 59.1 0.3 1.2 1 0 0 1 1 1 1 Profilin TFIIA PF03153.8 EGC31474.1 - 4.1 7.1 14.7 5.9 6.6 10.2 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Actin PF00022.14 EGC31475.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC31475.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) zf-C3HC4_3 PF13920.1 EGC31476.1 - 7.6e-08 31.9 6.0 1.2e-07 31.2 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC31476.1 - 2.9e-06 27.0 7.3 4.8e-06 26.3 5.0 1.4 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC31476.1 - 9.8e-05 22.0 8.2 0.00019 21.1 5.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC31476.1 - 0.00031 20.3 8.6 0.00069 19.2 5.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31476.1 - 0.00067 19.6 10.1 0.0011 18.9 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-LITAF-like PF10601.4 EGC31476.1 - 0.02 14.7 2.3 24 4.8 0.0 2.4 2 0 0 2 2 2 0 LITAF-like zinc ribbon domain zf-rbx1 PF12678.2 EGC31476.1 - 0.02 14.9 7.9 0.061 13.4 5.5 1.9 1 1 0 1 1 1 0 RING-H2 zinc finger AKAP2_C PF15304.1 EGC31476.1 - 0.04 13.5 11.0 0.051 13.1 7.6 1.1 1 0 0 1 1 1 0 A-kinase anchor protein 2 C-terminus zf-C3HC4_4 PF15227.1 EGC31476.1 - 0.18 11.7 8.5 1.6 8.6 6.2 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC31476.1 - 0.21 11.1 3.5 0.66 9.5 2.4 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1049 PF06305.6 EGC31476.1 - 0.21 11.0 0.0 0.21 11.0 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1049) FYVE_2 PF02318.11 EGC31476.1 - 0.28 11.1 6.7 0.47 10.3 4.7 1.3 1 0 0 1 1 1 0 FYVE-type zinc finger zf-RING_4 PF14570.1 EGC31476.1 - 0.45 10.1 9.0 0.14 11.7 3.3 2.0 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC31476.1 - 0.62 9.9 7.2 0.16 11.8 2.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger PAT1 PF09770.4 EGC31476.1 - 6.5 4.8 26.8 8.1 4.5 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hexapep PF00132.19 EGC31477.1 - 1.8e-09 36.6 14.3 1.7e-05 24.0 0.3 4.3 2 2 0 3 3 3 3 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGC31477.1 - 0.0024 17.4 5.1 0.0024 17.4 3.5 3.4 2 2 1 3 3 3 2 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGC31477.1 - 0.015 13.8 0.4 0.019 13.5 0.3 1.2 1 0 0 1 1 1 0 L-fucokinase IucA_IucC PF04183.7 EGC31478.1 - 2.2e-48 164.7 0.0 3.2e-48 164.1 0.0 1.3 1 0 0 1 1 1 1 IucA / IucC family FhuF PF06276.7 EGC31478.1 - 1.3e-17 64.1 0.0 3.5e-17 62.8 0.0 1.6 2 0 0 2 2 2 1 Ferric iron reductase FhuF-like transporter Acetyltransf_1 PF00583.19 EGC31479.1 - 1.4e-13 50.6 0.0 2.5e-13 49.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC31479.1 - 1.2e-07 31.7 0.1 1.9e-07 31.1 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC31479.1 - 2.7e-07 30.6 0.2 4.7e-07 29.8 0.1 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC31479.1 - 1e-05 25.7 0.0 1.4e-05 25.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC31479.1 - 4.2e-05 23.6 0.0 5.6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC31479.1 - 0.0008 19.1 0.0 0.0013 18.4 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EGC31479.1 - 0.018 14.9 0.0 0.036 13.9 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGC31479.1 - 0.058 13.2 0.0 0.39 10.5 0.0 1.9 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC31479.1 - 0.1 12.5 0.0 0.15 11.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Pkinase PF00069.20 EGC31480.1 - 8.4e-58 195.5 0.0 1.8e-57 194.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31480.1 - 4.3e-56 189.8 0.0 3.5e-55 186.8 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Ank_2 PF12796.2 EGC31480.1 - 2.8e-20 72.4 6.4 1e-09 38.5 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC31480.1 - 3e-14 52.6 2.3 1.4e-06 28.3 0.1 5.9 3 1 2 5 5 5 3 Ankyrin repeats (many copies) Ank PF00023.25 EGC31480.1 - 1.3e-13 50.0 9.3 2.9e-08 33.0 0.2 6.2 7 0 0 7 7 7 2 Ankyrin repeat Ank_4 PF13637.1 EGC31480.1 - 9.9e-13 48.2 16.0 0.00025 21.4 0.0 6.2 4 2 3 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC31480.1 - 5.4e-12 44.7 7.0 0.00014 21.8 0.1 6.4 6 0 0 6 6 6 3 Ankyrin repeat Kinase-like PF14531.1 EGC31480.1 - 0.0037 16.2 0.0 0.0072 15.3 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC31480.1 - 0.026 14.2 0.0 0.053 13.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Sod_Cu PF00080.15 EGC31481.1 - 1.1e-43 148.8 3.1 1.2e-43 148.6 2.1 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) PHD PF00628.24 EGC31483.1 - 9.6e-15 54.0 26.6 5.2e-07 29.2 3.4 3.7 3 0 0 3 3 3 3 PHD-finger zf-HC5HC2H PF13771.1 EGC31483.1 - 3.1e-11 43.2 27.1 0.00033 20.7 1.6 3.9 1 1 2 3 3 3 3 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EGC31483.1 - 3.1e-08 33.5 25.8 0.0035 17.3 1.3 3.9 1 1 2 3 3 3 3 PHD-zinc-finger like domain BAF1_ABF1 PF04684.8 EGC31483.1 - 1.5e-05 24.1 30.5 2.7e-05 23.2 21.1 1.5 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor zf-RING_2 PF13639.1 EGC31483.1 - 2.1 8.2 28.3 0.075 12.8 0.4 3.8 3 1 0 3 3 3 0 Ring finger domain Trypan_PARP PF05887.6 EGC31484.1 - 0.0055 16.5 8.8 0.0055 16.5 6.1 3.2 3 0 0 3 3 3 2 Procyclic acidic repetitive protein (PARP) Nucleoporin_FG PF13634.1 EGC31484.1 - 4.3 7.5 65.4 1.5e+04 -20.7 45.3 3.0 1 1 0 1 1 1 0 Nucleoporin FG repeat region Tir_receptor_M PF03549.9 EGC31485.1 - 1.4 9.0 3.7 4.6 7.4 0.0 2.9 3 0 0 3 3 3 0 Translocated intimin receptor (Tir) intimin-binding domain HNH_3 PF13392.1 EGC31486.1 - 1.3e-08 34.0 1.2 1.8e-08 33.6 0.8 1.3 1 0 0 1 1 1 1 HNH endonuclease HNH PF01844.18 EGC31486.1 - 0.14 12.0 1.3 0.22 11.4 0.9 1.4 1 0 0 1 1 1 0 HNH endonuclease DDE_Tnp_4 PF13359.1 EGC31487.1 - 2.7e-12 46.5 0.0 3.7e-12 46.1 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC31487.1 - 0.00038 20.0 0.5 0.0021 17.6 0.3 1.9 1 1 0 1 1 1 1 Transposase DDE domain DDE_Tnp_1_2 PF13586.1 EGC31487.1 - 0.072 13.2 0.1 0.17 12.0 0.0 1.7 1 1 0 1 1 1 0 Transposase DDE domain B-block_TFIIIC PF04182.7 EGC31487.1 - 0.089 12.6 0.2 0.19 11.5 0.0 1.6 2 0 0 2 2 2 0 B-block binding subunit of TFIIIC DUF3430 PF11912.3 EGC31489.1 - 3e-30 105.6 25.5 3e-30 105.6 17.7 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3430) UvrC_HhH_N PF08459.6 EGC31490.1 - 0.069 12.6 0.0 4.5 6.7 0.0 2.3 2 0 0 2 2 2 0 UvrC Helix-hairpin-helix N-terminal zf-RING_2 PF13639.1 EGC31492.1 - 1.3e-11 44.1 7.3 2.1e-11 43.4 5.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31492.1 - 1.1e-08 34.6 5.8 1.7e-08 34.0 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31492.1 - 3.6e-08 33.4 5.8 8.7e-08 32.1 4.0 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC31492.1 - 6.1e-08 32.1 10.4 1.2e-07 31.2 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31492.1 - 5e-07 29.6 9.7 8.2e-07 28.9 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31492.1 - 5.8e-07 29.1 8.8 1e-06 28.3 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC31492.1 - 0.00041 19.9 1.5 0.0022 17.6 1.0 2.4 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC31492.1 - 0.00064 19.5 9.3 0.0013 18.6 5.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC31492.1 - 0.00089 18.7 11.0 0.0016 17.9 7.7 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC31492.1 - 0.0043 16.8 2.2 0.011 15.5 1.6 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Tetraspannin PF00335.15 EGC31492.1 - 0.0098 15.1 0.2 0.069 12.4 0.0 2.2 2 0 0 2 2 2 1 Tetraspanin family Prok-RING_4 PF14447.1 EGC31492.1 - 0.019 14.4 4.8 0.052 13.1 3.3 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 CAF-1_p150 PF11600.3 EGC31492.1 - 0.14 11.5 61.7 0.015 14.7 26.5 2.3 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Chordopox_A13L PF05961.6 EGC31492.1 - 0.18 11.7 0.1 0.18 11.7 0.1 4.1 4 1 1 5 5 5 0 Chordopoxvirus A13L protein ODV-E18 PF10717.4 EGC31492.1 - 0.98 8.8 7.9 3.5 7.1 5.5 2.0 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 EphA2_TM PF14575.1 EGC31492.1 - 1.4 9.3 0.0 1.4 9.3 0.0 4.1 3 2 1 4 4 3 0 Ephrin type-A receptor 2 transmembrane domain DUF1272 PF06906.6 EGC31492.1 - 1.5 8.6 7.8 3.1 7.7 5.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Citrate_synt PF00285.16 EGC31493.1 - 5e-128 426.7 0.0 6e-128 426.5 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Cas_GSU0053 PF09617.5 EGC31493.1 - 0.15 11.8 0.1 1.9 8.2 0.0 2.2 2 0 0 2 2 2 0 CRISPR-associated protein GSU0053 (Cas_GSU0053) Chlam_PMP PF02415.12 EGC31496.1 - 0.00097 19.2 61.6 0.22 11.8 3.1 9.2 9 0 0 9 9 9 5 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat SKG6 PF08693.5 EGC31496.1 - 0.0019 17.4 0.0 0.0045 16.2 0.0 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain zf-UBR PF02207.15 EGC31497.1 - 4.8e-14 51.8 18.0 4.8e-14 51.8 12.5 2.3 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) DUF3439 PF11921.3 EGC31497.1 - 0.0075 16.0 8.0 0.018 14.7 5.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC31497.1 - 2.2 8.0 18.9 4.1 7.1 13.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein RhoGEF PF00621.15 EGC31498.1 - 2.4e-40 138.3 7.6 2.4e-40 138.3 5.2 4.7 3 1 1 5 5 5 1 RhoGEF domain OmpH PF03938.9 EGC31498.1 - 0.003 17.4 5.5 0.003 17.4 3.8 6.9 3 1 2 5 5 5 1 Outer membrane protein (OmpH-like) F-box-like PF12937.2 EGC31499.1 - 1.4e-05 24.7 0.1 2.7e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 F-box-like PRANC PF09372.5 EGC31499.1 - 0.0028 17.6 1.0 0.0028 17.6 0.7 3.3 2 1 1 3 3 3 1 PRANC domain F-box PF00646.28 EGC31499.1 - 0.014 15.0 0.1 0.036 13.7 0.0 1.7 1 0 0 1 1 1 0 F-box domain BTK PF00779.14 EGC31499.1 - 0.018 14.6 2.5 0.018 14.6 1.7 1.8 2 0 0 2 2 2 0 BTK motif RNA_polI_A34 PF08208.6 EGC31500.1 - 3.2e-22 79.1 61.1 3.2e-22 79.1 42.4 3.0 1 1 1 2 2 2 1 DNA-directed RNA polymerase I subunit RPA34.5 BAR PF03114.13 EGC31501.1 - 8.8e-08 31.9 12.0 1.4e-07 31.2 8.3 1.3 1 0 0 1 1 1 1 BAR domain DUF4047 PF13256.1 EGC31501.1 - 0.9 9.5 11.3 0.087 12.7 3.5 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF4047) Macoilin PF09726.4 EGC31501.1 - 5 5.2 37.7 1.9 6.6 18.8 2.1 2 0 0 2 2 2 0 Transmembrane protein Trypan_PARP PF05887.6 EGC31502.1 - 0.9 9.3 9.1 2.2 8.0 2.6 2.2 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) AIG2 PF06094.7 EGC31503.1 - 2.1e-07 31.3 0.1 4.4e-07 30.3 0.1 1.6 1 1 0 1 1 1 1 AIG2-like family Ig_J_chain PF15097.1 EGC31503.1 - 0.094 12.3 0.1 0.23 11.0 0.0 1.7 2 0 0 2 2 2 0 Immunoglobulin J chain GATase_7 PF13537.1 EGC31504.1 - 0.059 13.0 0.8 8.3 6.1 0.0 2.8 3 0 0 3 3 3 0 Glutamine amidotransferase domain AAA PF00004.24 EGC31505.1 - 1.5e-39 135.2 0.0 2.1e-39 134.7 0.0 1.2 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC31505.1 - 4e-08 34.1 0.0 9.2e-08 32.9 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC31505.1 - 1.1e-07 32.1 0.1 0.014 15.5 0.0 2.8 2 1 1 3 3 3 2 AAA domain RuvB_N PF05496.7 EGC31505.1 - 1.2e-06 27.8 0.0 7.3e-06 25.1 0.0 1.9 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGC31505.1 - 5.9e-05 23.0 0.0 0.00012 22.0 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EGC31505.1 - 7.2e-05 23.1 0.0 0.00015 22.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC31505.1 - 0.00018 21.4 0.1 0.00078 19.3 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_33 PF13671.1 EGC31505.1 - 0.00026 20.8 0.0 0.00039 20.3 0.0 1.4 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGC31505.1 - 0.00027 20.8 0.0 0.00043 20.1 0.0 1.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit AAA_5 PF07728.9 EGC31505.1 - 0.00028 20.6 0.1 0.0098 15.6 0.1 2.6 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC31505.1 - 0.00066 19.7 0.0 0.03 14.3 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_19 PF13245.1 EGC31505.1 - 0.00083 19.0 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain IstB_IS21 PF01695.12 EGC31505.1 - 0.0018 17.7 0.0 0.0028 17.0 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGC31505.1 - 0.002 17.3 0.1 0.0039 16.3 0.1 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGC31505.1 - 0.0049 17.0 0.0 0.011 15.8 0.0 1.8 1 1 0 1 1 1 1 RNA helicase SKI PF01202.17 EGC31505.1 - 0.0059 16.4 0.0 0.013 15.3 0.0 1.6 1 0 0 1 1 1 1 Shikimate kinase Parvo_NS1 PF01057.12 EGC31505.1 - 0.0085 14.9 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 AAA_28 PF13521.1 EGC31505.1 - 0.015 15.2 0.0 0.048 13.6 0.0 1.7 1 1 1 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGC31505.1 - 0.019 14.0 0.0 0.031 13.3 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_25 PF13481.1 EGC31505.1 - 0.02 14.3 0.3 0.14 11.5 0.1 2.1 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGC31505.1 - 0.021 14.3 0.0 0.11 11.9 0.0 2.1 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_11 PF13086.1 EGC31505.1 - 0.023 14.2 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain TIP49 PF06068.8 EGC31505.1 - 0.029 13.0 0.1 0.086 11.5 0.0 1.6 1 1 1 2 2 2 0 TIP49 C-terminus NACHT PF05729.7 EGC31505.1 - 0.037 13.6 0.2 0.17 11.5 0.0 2.0 2 0 0 2 2 2 0 NACHT domain IPT PF01745.11 EGC31505.1 - 0.056 12.6 0.0 0.55 9.3 0.0 2.2 2 0 0 2 2 2 0 Isopentenyl transferase AAA_3 PF07726.6 EGC31505.1 - 0.078 12.5 0.0 0.19 11.3 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PhoH PF02562.11 EGC31505.1 - 0.086 12.0 0.2 0.18 10.9 0.2 1.7 1 1 0 1 1 1 0 PhoH-like protein AAA_30 PF13604.1 EGC31505.1 - 0.086 12.4 0.2 0.17 11.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGC31505.1 - 0.11 12.0 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGC31505.1 - 0.12 11.5 0.5 1.6 7.7 0.1 2.2 1 1 0 2 2 2 0 KaiC Nrf1_DNA-bind PF10491.4 EGC31505.1 - 0.14 11.2 0.0 0.23 10.5 0.0 1.3 1 0 0 1 1 1 0 NLS-binding and DNA-binding and dimerisation domains of Nrf1 AAA_23 PF13476.1 EGC31505.1 - 0.2 11.9 3.5 0.15 12.3 0.3 2.1 1 1 1 2 2 2 0 AAA domain Frataxin_Cyay PF01491.11 EGC31506.1 - 2.6e-28 97.9 0.3 6.2e-28 96.7 0.0 1.7 2 0 0 2 2 2 1 Frataxin-like domain PCRF PF03462.13 EGC31506.1 - 0.045 13.4 0.1 0.69 9.6 0.0 2.2 2 1 0 2 2 2 0 PCRF domain DUF2392 PF10288.4 EGC31506.1 - 0.063 13.6 1.8 1.2 9.4 0.0 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF2392) NTPase_P4 PF11602.3 EGC31506.1 - 0.12 11.3 0.0 0.16 10.9 0.0 1.1 1 0 0 1 1 1 0 ATPase P4 of dsRNA bacteriophage phi-12 zf-TRAF PF02176.13 EGC31507.1 - 2.4e-19 69.4 15.7 5.9e-14 52.1 3.9 4.3 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.11 EGC31507.1 - 4.9e-06 26.3 13.3 0.00032 20.4 3.7 3.8 3 1 1 4 4 4 3 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EGC31507.1 - 1e-05 25.0 10.4 1e-05 25.0 7.2 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31507.1 - 3.2e-05 23.8 14.4 3.2e-05 23.8 10.0 4.4 3 1 3 6 6 6 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC31507.1 - 0.0062 16.3 10.8 0.0062 16.3 7.5 3.3 3 0 0 3 3 3 1 Ring finger domain MATH PF00917.21 EGC31507.1 - 0.008 16.4 2.5 0.008 16.4 1.7 2.5 3 0 0 3 3 3 1 MATH domain zf-TRAF PF02176.13 EGC31508.1 - 9.6e-13 48.3 6.3 9.6e-13 48.3 4.4 3.9 2 1 3 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC31508.1 - 3.2e-06 27.0 14.7 3.2e-06 27.0 10.2 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31508.1 - 1.7e-05 24.3 10.8 1.7e-05 24.3 7.5 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MATH PF00917.21 EGC31508.1 - 0.00039 20.6 3.5 0.00039 20.6 2.4 2.1 2 0 0 2 2 2 1 MATH domain zf-RING_2 PF13639.1 EGC31508.1 - 0.004 16.9 11.5 0.004 16.9 8.0 3.5 3 0 0 3 3 3 1 Ring finger domain Sina PF03145.11 EGC31508.1 - 0.072 12.7 0.1 0.072 12.7 0.0 4.1 2 1 3 5 5 5 0 Seven in absentia protein family zf-TRAF PF02176.13 EGC31509.1 - 2.5e-18 66.2 17.0 1.7e-14 53.8 5.1 4.5 2 1 3 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC31509.1 - 6.9e-07 29.1 13.8 6.9e-07 29.1 9.5 4.0 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31509.1 - 1.1e-06 28.1 10.5 1.1e-06 28.1 7.2 3.4 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC31509.1 - 0.00011 21.9 20.0 0.038 13.6 0.1 4.3 2 1 2 4 4 4 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC31509.1 - 0.002 17.8 11.5 0.002 17.8 8.0 3.2 3 1 0 3 3 3 1 Ring finger domain NTP_transf_4 PF13562.1 EGC31509.1 - 0.067 12.8 0.1 0.21 11.1 0.0 1.9 2 0 0 2 2 2 0 Sugar nucleotidyl transferase zf-TRAF PF02176.13 EGC31510.1 - 2.1e-19 69.6 17.9 9e-14 51.5 4.8 4.8 3 2 2 5 5 5 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC31510.1 - 1.9e-07 30.9 14.1 1.9e-07 30.9 9.8 4.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31510.1 - 7.8e-07 28.6 11.4 7.8e-07 28.6 7.9 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC31510.1 - 0.00058 19.5 1.1 0.00058 19.5 0.8 3.9 2 1 3 5 5 5 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC31510.1 - 0.0027 17.4 11.8 0.0027 17.4 8.2 3.4 4 1 0 4 4 4 1 Ring finger domain NTP_transf_4 PF13562.1 EGC31510.1 - 0.027 14.1 0.2 0.062 12.9 0.0 1.7 2 0 0 2 2 2 0 Sugar nucleotidyl transferase CCDC155 PF14662.1 EGC31510.1 - 0.19 11.3 8.6 0.019 14.5 2.0 2.0 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 zf-TRAF PF02176.13 EGC31511.1 - 5e-18 65.2 15.0 3.2e-13 49.8 5.0 4.1 2 1 2 4 4 4 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC31511.1 - 2.9e-05 24.0 14.7 2.9e-05 24.0 10.2 3.8 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31511.1 - 0.00013 21.6 10.3 0.00013 21.6 7.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC31511.1 - 0.0086 15.8 11.1 0.0086 15.8 7.7 3.2 3 0 0 3 3 3 1 Ring finger domain CCDC155 PF14662.1 EGC31511.1 - 0.0095 15.5 12.4 0.45 10.0 2.7 2.7 1 1 1 2 2 2 2 Coiled-coil region of CCDC155 Sina PF03145.11 EGC31511.1 - 0.037 13.6 0.2 0.027 14.1 2.8 4.0 2 1 1 4 4 4 0 Seven in absentia protein family Transgly PF00912.17 EGC31511.1 - 0.052 12.8 1.3 2.5 7.3 0.1 2.3 1 1 1 2 2 2 0 Transglycosylase Myosin_tail_1 PF01576.14 EGC31511.1 - 0.17 9.5 11.8 0.77 7.4 8.2 1.8 1 1 0 1 1 1 0 Myosin tail p450 PF00067.17 EGC31512.1 - 1.2e-100 337.2 0.1 1.5e-100 336.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-TRAF PF02176.13 EGC31513.1 - 4.4e-17 62.2 27.0 1.9e-12 47.3 4.3 4.5 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC31513.1 - 1.5e-06 28.1 13.8 1.5e-06 28.1 9.6 4.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31513.1 - 3.2e-06 26.6 10.9 3.2e-06 26.6 7.5 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC31513.1 - 0.00066 19.3 0.9 0.00066 19.3 0.6 3.7 3 1 1 4 4 4 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC31513.1 - 0.0043 16.8 11.4 0.0043 16.8 7.9 3.8 4 1 1 5 5 5 1 Ring finger domain CCDC155 PF14662.1 EGC31513.1 - 0.012 15.1 2.9 0.012 15.1 2.0 1.8 2 0 0 2 2 2 0 Coiled-coil region of CCDC155 DUF3450 PF11932.3 EGC31513.1 - 0.058 12.6 0.4 0.085 12.1 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) RCC1_2 PF13540.1 EGC31514.1 - 5.7e-27 92.7 10.1 6.8e-11 41.4 1.1 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGC31514.1 - 2.4e-20 72.4 1.3 0.00013 22.0 0.0 7.3 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGC31514.1 - 9.5e-08 32.0 8.4 8.6e-07 28.9 0.1 4.3 4 0 0 4 4 4 1 BTB/POZ domain GRASP55_65 PF04495.9 EGC31515.1 - 1.4e-69 232.4 0.1 5.9e-51 172.0 0.0 2.3 1 1 1 2 2 2 2 GRASP55/65 PDZ-like domain PDZ_2 PF13180.1 EGC31515.1 - 0.00041 20.1 0.0 0.021 14.7 0.0 2.5 2 0 0 2 2 2 1 PDZ domain Curto_V2 PF07325.6 EGC31516.1 - 0.081 12.5 1.5 0.34 10.5 0.9 1.9 1 1 0 1 1 1 0 Curtovirus V2 protein DUF2536 PF10750.4 EGC31518.1 - 0.058 12.9 3.1 0.068 12.7 0.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) PD-C2-AF1 PF09310.5 EGC31518.1 - 0.21 10.7 3.9 0.25 10.4 2.7 1.1 1 0 0 1 1 1 0 POU domain, class 2, associating factor 1 Lzipper-MIP1 PF14389.1 EGC31518.1 - 1.7 8.8 6.7 0.28 11.2 1.9 1.8 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 Hid1 PF12722.2 EGC31519.1 - 2 5.9 18.7 2.6 5.6 12.9 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CobT PF06213.7 EGC31519.1 - 2 7.4 15.8 2.5 7.1 10.9 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT K_channel_TID PF07941.6 EGC31520.1 - 0.08 13.1 2.7 0.098 12.8 1.8 1.2 1 0 0 1 1 1 0 Potassium channel Kv1.4 tandem inactivation domain Brr6_like_C_C PF10104.4 EGC31522.1 - 1.5e-09 37.5 19.8 1.5e-09 37.5 0.5 3.4 2 1 1 3 3 3 2 Di-sulfide bridge nucleocytoplasmic transport domain DUF3899 PF13038.1 EGC31522.1 - 0.78 9.9 14.3 3.4 7.8 5.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3899) DUF2615 PF11027.3 EGC31522.1 - 0.79 9.6 6.2 0.72 9.8 0.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Shisa PF13908.1 EGC31522.1 - 0.99 9.5 0.0 0.99 9.5 0.0 2.3 2 1 1 3 3 3 0 Wnt and FGF inhibitory regulator Scs3p PF10261.4 EGC31522.1 - 1.3 8.0 6.3 16 4.4 4.4 2.0 1 1 0 1 1 1 0 Inositol phospholipid synthesis and fat-storage-inducing TM DUF912 PF06024.7 EGC31522.1 - 6.2 6.9 23.3 0.18 11.8 8.1 2.7 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4064 PF13273.1 EGC31522.1 - 7.3 6.7 11.3 1.8 8.7 3.7 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Cadherin-like PF12733.2 EGC31524.1 - 0.0019 18.4 2.6 2.8 8.2 0.2 4.2 4 0 0 4 4 4 2 Cadherin-like beta sandwich domain DUF2057 PF09829.4 EGC31524.1 - 0.0025 17.5 0.0 3.5 7.2 0.0 2.7 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2057) C2 PF00168.25 EGC31526.1 - 0.023 14.5 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 C2 domain DNase_II PF03265.10 EGC31528.1 - 1.5e-35 122.7 18.3 3.1e-30 105.2 9.0 2.7 2 1 0 2 2 2 2 Deoxyribonuclease II Pox_A12 PF04651.8 EGC31529.1 - 6.3 6.8 17.2 7.6 6.6 11.9 1.3 1 0 0 1 1 1 0 Poxvirus A12 protein Usp PF00582.21 EGC31531.1 - 5.7e-19 68.6 0.1 7.9e-19 68.2 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family XisH PF08814.5 EGC31531.1 - 0.0059 16.6 0.1 0.0075 16.2 0.0 1.2 1 0 0 1 1 1 1 XisH protein HyaE PF07449.6 EGC31531.1 - 0.019 14.8 0.0 0.027 14.3 0.0 1.4 1 0 0 1 1 1 0 Hydrogenase-1 expression protein HyaE PAP2 PF01569.16 EGC31532.1 - 1.9e-19 69.6 2.5 1.9e-19 69.6 1.7 1.7 2 0 0 2 2 2 1 PAP2 superfamily DUF3687 PF12459.3 EGC31532.1 - 0.023 13.9 0.9 0.093 11.9 0.6 2.1 1 0 0 1 1 1 0 D-Ala-teichoic acid biosynthesis protein DUF212 PF02681.9 EGC31532.1 - 0.023 14.4 0.3 0.42 10.3 0.0 2.3 2 0 0 2 2 2 0 Divergent PAP2 family DUF1576 PF07613.6 EGC31532.1 - 0.22 11.0 3.9 0.079 12.4 0.6 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1576) CUE PF02845.11 EGC31533.1 - 1.4e-13 50.0 0.1 4.9e-13 48.2 0.1 2.1 1 0 0 1 1 1 1 CUE domain UPF0697 PF15117.1 EGC31533.1 - 1.1 9.0 7.9 2.7 7.7 5.5 1.6 1 0 0 1 1 1 0 Uncharacterised protein family UPF0697 UDP-g_GGTase PF06427.6 EGC31534.1 - 1.7e-58 197.4 0.5 4.9e-58 195.9 0.4 1.9 1 0 0 1 1 1 1 UDP-glucose:Glycoprotein Glucosyltransferase Glyco_transf_8 PF01501.15 EGC31534.1 - 1.5e-07 31.0 0.8 8.8e-07 28.5 0.5 2.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 ubiquitin PF00240.18 EGC31534.1 - 0.00075 18.8 0.5 0.91 8.9 0.1 2.9 2 0 0 2 2 2 2 Ubiquitin family WG_beta_rep PF14903.1 EGC31534.1 - 0.0026 17.9 0.2 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 WG containing repeat PAC2 PF09754.4 EGC31535.1 - 6e-25 88.3 0.0 1e-24 87.6 0.0 1.4 2 0 0 2 2 2 1 PAC2 family ATP-grasp_2 PF08442.5 EGC31536.1 - 8.2e-75 250.6 2.6 1.2e-74 250.0 1.8 1.3 1 0 0 1 1 1 1 ATP-grasp domain Ligase_CoA PF00549.14 EGC31536.1 - 3.9e-27 94.7 1.7 8.2e-27 93.6 1.2 1.6 1 0 0 1 1 1 1 CoA-ligase ATP-grasp_5 PF13549.1 EGC31536.1 - 3.9e-13 49.1 0.4 6.5e-13 48.3 0.3 1.3 1 0 0 1 1 1 1 ATP-grasp domain GARS_A PF01071.14 EGC31536.1 - 5.1e-05 22.9 1.9 0.00018 21.1 1.4 1.9 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain ATPgrasp_Ter PF15632.1 EGC31536.1 - 0.016 14.0 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp_4 PF13535.1 EGC31536.1 - 0.023 14.4 0.0 0.045 13.4 0.0 1.5 1 0 0 1 1 1 0 ATP-grasp domain ATP-grasp PF02222.17 EGC31536.1 - 0.046 13.0 0.2 0.1 11.9 0.1 1.7 1 1 0 1 1 1 0 ATP-grasp domain SDH_alpha PF03313.10 EGC31536.1 - 0.12 11.3 1.8 0.16 11.0 0.2 1.9 2 1 1 3 3 3 0 Serine dehydratase alpha chain CENP-O PF09496.5 EGC31537.1 - 1.7e-06 28.1 2.8 1.9e-06 27.9 0.4 2.2 2 0 0 2 2 2 1 Cenp-O kinetochore centromere component Alpha-amylase_C PF02806.13 EGC31539.1 - 1.4e-21 76.3 0.6 1.1e-20 73.5 0.0 2.4 2 0 0 2 2 2 1 Alpha amylase, C-terminal all-beta domain Alpha-amylase PF00128.19 EGC31539.1 - 9.2e-19 67.9 0.0 1.1e-15 57.8 0.1 2.5 1 1 1 2 2 2 2 Alpha amylase, catalytic domain CBM_48 PF02922.13 EGC31539.1 - 4.7e-14 52.2 0.3 9.1e-14 51.2 0.2 1.5 1 0 0 1 1 1 1 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) hDGE_amylase PF14701.1 EGC31539.1 - 0.053 12.4 0.1 0.098 11.5 0.1 1.3 1 0 0 1 1 1 0 glucanotransferase domain of human glycogen debranching enzyme Atrophin-1 PF03154.10 EGC31540.1 - 0.0018 16.5 1.6 0.0018 16.5 1.1 2.0 2 0 0 2 2 2 1 Atrophin-1 family CDV3 PF15359.1 EGC31540.1 - 0.007 16.4 0.5 0.017 15.2 0.4 1.6 1 0 0 1 1 1 1 Carnitine deficiency-associated protein 3 Med3 PF11593.3 EGC31540.1 - 0.016 14.4 5.3 0.035 13.3 3.7 1.6 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.12 EGC31540.1 - 0.21 11.3 24.2 0.37 10.5 16.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Herpes_capsid PF06112.6 EGC31540.1 - 5 7.1 8.4 32 4.5 3.4 2.2 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein DUF3447 PF11929.3 EGC31540.1 - 9.8 6.0 12.7 4.7 7.0 0.5 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF3447) LEA_1 PF03760.10 EGC31541.1 - 0.66 10.1 4.0 6.2 7.0 0.1 3.0 3 0 0 3 3 3 0 Late embryogenesis abundant (LEA) group 1 CN_hydrolase PF00795.17 EGC31542.1 - 1.9e-32 112.1 0.1 3.1e-32 111.4 0.1 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase DUF1101 PF06503.6 EGC31542.1 - 0.028 13.2 0.0 0.05 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1101) DUF3310 PF11753.3 EGC31543.1 - 0.012 15.5 0.2 0.028 14.3 0.1 1.6 1 0 0 1 1 1 0 Protein of unknwon function (DUF3310) Bravo_FIGEY PF13882.1 EGC31543.1 - 2.2 9.2 7.5 10 7.1 0.3 2.2 1 1 1 2 2 2 0 Bravo-like intracellular region HATPase_c PF02518.21 EGC31544.1 - 1.3e-25 89.2 0.1 2.3e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGC31544.1 - 4.3e-19 68.2 0.0 1.2e-18 66.8 0.0 1.8 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Response_reg PF00072.19 EGC31544.1 - 5.4e-19 68.2 3.4 1.6e-18 66.7 0.2 2.6 2 0 0 2 2 2 1 Response regulator receiver domain PAS_9 PF13426.1 EGC31544.1 - 2.4e-09 37.4 0.0 3.9e-07 30.3 0.0 2.9 2 0 0 2 2 2 1 PAS domain PAS_3 PF08447.6 EGC31544.1 - 0.019 15.0 0.0 0.35 10.9 0.0 2.4 2 0 0 2 2 2 0 PAS fold PG_binding_1 PF01471.13 EGC31545.1 - 9.4e-07 28.7 0.0 0.00022 21.1 0.0 3.6 4 0 0 4 4 4 2 Putative peptidoglycan binding domain DUF4208 PF13907.1 EGC31546.1 - 0.055 13.6 0.3 0.09 12.9 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Corona_S2 PF01601.11 EGC31546.1 - 0.15 10.1 1.7 0.17 9.9 1.2 1.0 1 0 0 1 1 1 0 Coronavirus S2 glycoprotein PQ-loop PF04193.9 EGC31547.1 - 3.9e-17 61.5 27.9 2.2e-09 36.7 3.1 4.3 3 2 0 3 3 3 2 PQ loop repeat CLN5 PF15014.1 EGC31548.1 - 1.4e-32 113.2 10.6 1.4e-31 110.0 7.4 1.9 1 1 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 FNIP PF05725.7 EGC31549.1 - 4.6e-06 26.4 38.3 9.4e-05 22.2 0.2 8.5 7 2 3 10 10 10 5 FNIP Repeat Methyltransf_21 PF05050.7 EGC31550.1 - 0.0022 17.9 0.2 0.0055 16.6 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase FkbM domain Macoilin PF09726.4 EGC31550.1 - 2.1 6.5 12.4 3.4 5.8 8.6 1.3 1 0 0 1 1 1 0 Transmembrane protein OATP PF03137.15 EGC31551.1 - 0.012 13.7 1.0 0.02 12.9 0.7 1.3 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Secretin_N_2 PF07655.8 EGC31551.1 - 0.16 12.3 30.1 0.038 14.3 14.4 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain ETRAMP PF09716.5 EGC31551.1 - 4.7 7.2 18.7 0.1 12.5 6.9 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) CemA PF03040.9 EGC31551.1 - 6.6 6.2 16.2 1.9 8.0 2.8 2.1 1 1 1 2 2 2 0 CemA family Pex14_N PF04695.8 EGC31551.1 - 8.5 6.4 8.7 2.4 8.1 3.5 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Nucleoside_tran PF01733.13 EGC31551.1 - 9.5 5.2 6.7 3.3 6.7 2.5 1.7 1 1 1 2 2 2 0 Nucleoside transporter TRAP_beta PF05753.9 EGC31552.1 - 8.9e-46 155.3 2.0 1.1e-45 155.0 1.4 1.0 1 0 0 1 1 1 1 Translocon-associated protein beta (TRAPB) CARDB PF07705.6 EGC31552.1 - 0.074 13.1 0.0 0.14 12.2 0.0 1.4 1 1 0 1 1 1 0 CARDB Ribosomal_L19 PF01245.15 EGC31552.1 - 0.088 12.5 0.0 0.13 12.0 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L19 RGS PF00615.14 EGC31554.1 - 5.8e-49 165.1 29.9 2.1e-20 72.9 1.4 4.7 5 0 0 5 5 5 3 Regulator of G protein signaling domain DUF445 PF04286.7 EGC31554.1 - 1.7 8.0 6.8 0.86 9.0 0.2 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF445) bZIP_1 PF00170.16 EGC31556.1 - 2.7e-09 36.8 10.6 2.7e-09 36.8 7.3 2.3 1 1 1 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGC31556.1 - 4.2e-07 29.6 10.9 4.2e-07 29.6 7.6 2.7 3 0 0 3 3 3 1 Basic region leucine zipper TelA PF05816.6 EGC31556.1 - 0.0015 17.3 10.1 0.0025 16.5 7.0 1.2 1 0 0 1 1 1 1 Toxic anion resistance protein (TelA) CCDC155 PF14662.1 EGC31556.1 - 0.11 12.1 15.1 0.18 11.4 10.5 1.3 1 0 0 1 1 1 0 Coiled-coil region of CCDC155 DUF848 PF05852.6 EGC31556.1 - 0.67 9.8 9.0 1.3 8.8 6.3 1.5 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) RNase_HII PF01351.13 EGC31557.1 - 4.5e-43 147.2 0.0 5e-43 147.0 0.0 1.0 1 0 0 1 1 1 1 Ribonuclease HII CBM49 PF09478.5 EGC31558.1 - 1e-14 54.3 5.2 2.3e-14 53.2 3.6 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Glyco_hydro_9 PF00759.14 EGC31560.1 - 2.5e-143 478.2 11.4 2.8e-143 478.0 7.9 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 FNIP PF05725.7 EGC31561.1 - 9.8e-30 102.2 50.9 2.1e-13 49.9 4.1 6.4 2 2 4 7 7 7 6 FNIP Repeat B-block_TFIIIC PF04182.7 EGC31561.1 - 1.6 8.6 5.1 1.7 8.5 1.5 2.7 2 2 0 2 2 2 0 B-block binding subunit of TFIIIC adh_short PF00106.20 EGC31563.1 - 0.00044 20.2 0.0 0.00068 19.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Anillin PF08174.6 EGC31563.1 - 0.0039 17.2 1.2 0.012 15.6 0.8 1.8 1 0 0 1 1 1 1 Cell division protein anillin KR PF08659.5 EGC31563.1 - 0.03 13.9 0.0 0.05 13.2 0.0 1.2 1 0 0 1 1 1 0 KR domain Dimer_Tnp_hAT PF05699.9 EGC31565.1 - 9.8e-12 44.3 0.1 2.6e-11 42.9 0.1 1.7 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region DUF1510 PF07423.6 EGC31567.1 - 0.044 13.1 8.9 0.082 12.2 6.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) TMEM154 PF15102.1 EGC31568.1 - 0.00038 20.1 0.2 0.00067 19.3 0.1 1.4 1 0 0 1 1 1 1 TMEM154 protein family DIL PF01843.14 EGC31569.1 - 1.4e-25 89.1 2.9 1.4e-25 89.1 2.0 4.0 5 0 0 5 5 5 1 DIL domain NT-C2 PF10358.4 EGC31569.1 - 2.2e-20 72.5 2.8 2.2e-20 72.5 1.9 5.3 4 1 1 5 5 5 1 N-terminal C2 in EEIG1 and EHBP1 proteins TMF_TATA_bd PF12325.3 EGC31569.1 - 0.002 17.8 2.6 0.002 17.8 1.8 10.9 2 1 7 11 11 11 3 TATA element modulatory factor 1 TATA binding Pox_A_type_inc PF04508.7 EGC31569.1 - 0.027 14.2 0.6 0.027 14.2 0.4 13.6 15 1 0 15 15 15 0 Viral A-type inclusion protein repeat DUF3782 PF12644.2 EGC31569.1 - 1.1 9.0 0.0 1.1 9.0 0.0 9.7 3 3 1 4 4 4 0 Protein of unknown function (DUF3782) Myosin_tail_1 PF01576.14 EGC31569.1 - 5.7 4.5 192.9 0.12 10.0 4.1 4.2 2 1 2 4 4 4 0 Myosin tail DUF3439 PF11921.3 EGC31569.1 - 5.8 6.6 5.8 4.8 6.9 2.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) PRKCSH-like PF12999.2 EGC31570.1 - 3.1e-46 157.1 11.7 3.1e-46 157.1 8.1 2.4 2 1 0 3 3 3 1 Glucosidase II beta subunit-like PRKCSH_1 PF13015.1 EGC31570.1 - 1.5e-29 102.4 0.5 1.5e-29 102.4 0.3 2.0 2 0 0 2 2 2 1 Glucosidase II beta subunit-like protein Ldl_recept_a PF00057.13 EGC31570.1 - 0.00028 20.7 14.5 0.016 15.0 4.4 2.6 2 0 0 2 2 2 2 Low-density lipoprotein receptor domain class A PRKCSH PF07915.8 EGC31570.1 - 0.00036 21.2 1.4 0.00036 21.2 1.0 3.9 2 2 0 2 2 2 1 Glucosidase II beta subunit-like protein ERM PF00769.14 EGC31570.1 - 3.6 7.0 37.0 0.42 10.0 21.3 2.2 2 1 0 2 2 2 0 Ezrin/radixin/moesin family PH PF00169.24 EGC31571.1 - 3.4e-14 52.9 0.3 3.4e-14 52.9 0.2 1.9 2 1 0 2 2 2 1 PH domain SH3_1 PF00018.23 EGC31571.1 - 6e-13 47.9 3.2 1.7e-12 46.4 1.0 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGC31571.1 - 2.2e-09 36.7 2.1 7.7e-08 31.8 1.5 2.6 1 1 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC31571.1 - 7.6e-06 25.3 0.3 2.7e-05 23.5 0.2 2.0 1 1 0 1 1 1 1 Variant SH3 domain PH_8 PF15409.1 EGC31571.1 - 1.8e-05 24.7 0.1 3.8e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EGC31571.1 - 6.4e-05 23.1 5.4 0.00056 20.1 0.2 3.2 2 1 0 2 2 2 1 Pleckstrin homology domain MBD_C PF14048.1 EGC31571.1 - 0.022 15.3 0.7 0.043 14.4 0.5 1.4 1 0 0 1 1 1 0 C-terminal domain of methyl-CpG binding protein 2 and 3 SH3_3 PF08239.6 EGC31571.1 - 0.12 12.5 0.2 0.28 11.4 0.1 1.6 1 0 0 1 1 1 0 Bacterial SH3 domain PH_9 PF15410.1 EGC31571.1 - 0.12 12.4 3.6 0.31 11.1 1.1 2.7 1 1 1 2 2 2 0 Pleckstrin homology domain ThiF PF00899.16 EGC31572.1 - 4.3e-30 104.3 0.0 1.2e-29 102.8 0.0 1.8 1 0 0 1 1 1 1 ThiF family Shikimate_DH PF01488.15 EGC31572.1 - 0.0013 18.8 0.0 0.073 13.1 0.0 2.4 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase 2-Hacid_dh_C PF02826.14 EGC31572.1 - 0.0039 16.3 0.0 0.79 8.8 0.0 2.3 2 0 0 2 2 2 2 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EGC31572.1 - 0.024 14.9 0.0 0.1 12.8 0.0 2.0 1 1 0 1 1 1 0 Putative NAD(P)-binding Toprim PF01751.17 EGC31572.1 - 0.09 12.7 0.1 0.38 10.7 0.0 1.9 2 0 0 2 2 2 0 Toprim domain UQ_con PF00179.21 EGC31576.1 - 1.1e-37 128.6 0.8 1.3e-37 128.3 0.0 1.5 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGC31576.1 - 0.0021 17.7 0.1 0.0037 16.9 0.0 1.4 1 0 0 1 1 1 1 UEV domain RWD PF05773.17 EGC31576.1 - 0.0043 16.9 0.4 0.0067 16.3 0.2 1.5 1 1 0 1 1 1 1 RWD domain Bot1p PF12298.3 EGC31576.1 - 0.076 12.9 4.2 0.11 12.4 2.9 1.2 1 0 0 1 1 1 0 Eukaryotic mitochondrial regulator protein Pro-kuma_activ PF09286.6 EGC31577.1 - 2.3e-33 115.2 0.4 4.1e-33 114.4 0.3 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC31577.1 - 0.00067 18.8 9.7 0.0067 15.6 6.5 2.3 1 1 0 1 1 1 1 Subtilase family DUF775 PF05603.7 EGC31579.1 - 4e-46 157.0 5.4 5.1e-46 156.7 3.8 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF775) MPP6 PF10175.4 EGC31579.1 - 0.0078 16.5 0.0 0.013 15.8 0.0 1.3 1 0 0 1 1 1 1 M-phase phosphoprotein 6 DUF1212 PF06738.7 EGC31580.1 - 1.1e-37 129.4 10.9 4.7e-36 124.0 0.1 2.7 3 0 0 3 3 3 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGC31580.1 - 1.1e-22 80.4 32.4 1.4e-17 63.8 7.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) DASH_Dam1 PF08653.5 EGC31580.1 - 0.6 9.9 6.4 0.98 9.2 2.2 2.8 3 0 0 3 3 3 0 DASH complex subunit Dam1 ubiquitin PF00240.18 EGC31581.1 - 3.4e-15 55.2 2.6 5.4e-15 54.5 0.5 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EGC31581.1 - 2.8e-05 23.7 0.2 5.5e-05 22.7 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Sec15 PF04091.7 EGC31582.1 - 1.1e-73 248.2 18.0 1.1e-73 248.2 12.5 2.5 3 0 0 3 3 3 1 Exocyst complex subunit Sec15-like PRP38_assoc PF12871.2 EGC31583.1 - 0.00019 21.9 44.6 0.00019 21.9 30.9 2.5 3 0 0 3 3 3 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term CTD_bind PF04818.8 EGC31583.1 - 0.0021 18.2 0.7 0.015 15.5 0.0 3.0 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Talin_middle PF09141.5 EGC31583.1 - 0.028 14.0 0.3 0.052 13.2 0.2 1.5 1 0 0 1 1 1 0 Talin, middle domain CTK3 PF12243.3 EGC31584.1 - 0.0006 19.4 0.1 0.00066 19.3 0.1 1.2 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 DUF3647 PF12363.3 EGC31584.1 - 0.09 12.8 0.1 0.094 12.8 0.1 1.2 1 0 0 1 1 1 0 Phage protein RAB3GAP2_N PF14655.1 EGC31587.1 - 0.0062 15.5 2.8 0.012 14.6 2.0 1.4 1 0 0 1 1 1 1 Rab3 GTPase-activating protein regulatory subunit N-terminus Oligomerisation PF02410.10 EGC31589.1 - 3e-20 72.1 0.5 1.5e-19 69.8 0.4 2.3 1 0 0 1 1 1 1 Oligomerisation domain zf-RING_2 PF13639.1 EGC31590.1 - 6.3e-15 54.7 8.9 8.4e-15 54.3 6.2 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31590.1 - 1.3e-08 34.4 5.8 1.8e-08 33.9 4.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31590.1 - 3.3e-08 33.4 10.2 4.8e-08 32.9 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31590.1 - 3.5e-08 33.0 9.0 5e-08 32.5 6.3 1.2 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC31590.1 - 8.4e-06 25.3 9.8 1.8e-05 24.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31590.1 - 1.3e-05 25.2 9.4 3.4e-05 23.8 6.5 1.7 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC31590.1 - 2.2e-05 24.0 3.7 5.7e-05 22.7 2.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGC31590.1 - 0.014 15.1 5.4 0.032 14.0 3.7 1.6 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGC31590.1 - 0.015 15.3 5.0 0.042 13.8 3.5 1.7 1 1 0 1 1 1 0 RING-variant domain HNH_5 PF14279.1 EGC31590.1 - 0.068 13.1 2.3 0.074 13.0 1.3 1.4 1 1 0 1 1 1 0 HNH endonuclease zf-FCS PF06467.9 EGC31590.1 - 0.093 12.3 0.4 0.093 12.3 0.3 2.2 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif FANCL_C PF11793.3 EGC31590.1 - 0.21 11.5 9.1 2.8 7.9 6.3 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain zf-C3HC4_4 PF15227.1 EGC31590.1 - 0.94 9.4 9.1 1.9 8.4 6.3 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF912 PF06024.7 EGC31590.1 - 2.2 8.3 5.9 2.7 8.0 4.1 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) C1_3 PF07649.7 EGC31590.1 - 2.4 8.2 11.5 9.5 6.3 0.2 3.1 3 0 0 3 3 3 0 C1-like domain zf-RING_4 PF14570.1 EGC31590.1 - 3.4 7.3 8.4 5.3 6.7 5.8 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain Prok-RING_1 PF14446.1 EGC31590.1 - 4.3 7.1 10.1 6.7 6.5 1.2 2.4 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 DUF2408 PF10303.4 EGC31591.1 - 0.051 13.7 3.2 0.099 12.7 0.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2408) Sigma_reg_C PF13791.1 EGC31591.1 - 0.078 13.0 5.3 0.043 13.8 1.8 1.9 2 0 0 2 2 2 0 Sigma factor regulator C-terminal CASP_C PF08172.7 EGC31592.1 - 2.4e-54 183.9 1.1 2.8e-54 183.7 0.8 1.0 1 0 0 1 1 1 1 CASP C terminal DUF4164 PF13747.1 EGC31592.1 - 0.04 14.0 0.4 0.068 13.3 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4164) Bap31 PF05529.7 EGC31592.1 - 0.75 9.2 4.0 6.2 6.2 0.0 2.2 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like bZIP_1 PF00170.16 EGC31592.1 - 3.3 7.7 6.9 0.92 9.5 2.7 1.6 2 0 0 2 2 2 0 bZIP transcription factor Acetyltransf_7 PF13508.1 EGC31593.1 - 8.9e-10 38.6 0.3 1.6e-09 37.8 0.2 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC31593.1 - 0.0044 17.0 0.0 0.0076 16.2 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC31593.1 - 0.0051 16.9 0.0 0.0083 16.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC31593.1 - 0.017 14.9 0.0 0.028 14.3 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC31593.1 - 0.018 14.9 0.0 0.037 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC31593.1 - 0.018 14.7 0.0 0.037 13.7 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_4 PF13420.1 EGC31593.1 - 0.043 13.7 0.0 0.081 12.8 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Sec20 PF03908.8 EGC31594.1 - 3.1e-06 26.8 0.3 3.1e-06 26.8 0.2 2.4 2 1 1 3 3 3 1 Sec20 V-SNARE_C PF12352.3 EGC31594.1 - 8.4e-06 25.7 0.7 2e-05 24.5 0.4 1.8 1 1 0 1 1 1 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EGC31594.1 - 0.0014 18.7 1.4 0.0014 18.7 1.0 2.2 2 0 0 2 2 2 1 Vesicle transport v-SNARE protein N-terminus ODV-E18 PF10717.4 EGC31594.1 - 0.0015 17.9 1.6 0.0017 17.7 0.1 2.0 2 0 0 2 2 1 1 Occlusion-derived virus envelope protein ODV-E18 Ctr PF04145.10 EGC31594.1 - 0.0022 18.0 0.3 0.014 15.4 0.0 2.0 2 0 0 2 2 2 1 Ctr copper transporter family OppC_N PF12911.2 EGC31594.1 - 0.035 13.4 0.1 0.084 12.2 0.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Shisa PF13908.1 EGC31594.1 - 0.037 14.1 2.6 0.041 14.0 0.1 2.0 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator Laminin_II PF06009.7 EGC31594.1 - 0.041 13.6 5.0 2.1 8.1 0.5 2.2 2 0 0 2 2 2 0 Laminin Domain II DUF3753 PF12575.3 EGC31594.1 - 0.12 12.1 1.0 0.24 11.2 0.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) YlqD PF11068.3 EGC31594.1 - 0.15 12.1 8.1 0.3 11.1 1.7 2.3 2 0 0 2 2 2 0 YlqD protein SIT PF15330.1 EGC31594.1 - 0.19 11.8 3.1 1.2 9.2 0.0 2.6 2 1 1 3 3 3 0 SHP2-interacting transmembrane adaptor protein, SIT Glucosaminidase PF01832.15 EGC31594.1 - 0.19 11.8 4.1 0.71 9.9 1.0 2.2 2 0 0 2 2 2 0 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase EphA2_TM PF14575.1 EGC31594.1 - 0.21 11.9 0.7 0.76 10.2 0.0 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain TcdB_N PF12918.2 EGC31594.1 - 0.43 10.6 5.3 2 8.5 1.6 2.6 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain WXG100 PF06013.7 EGC31594.1 - 0.7 9.9 6.1 0.25 11.3 0.4 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF4472 PF14739.1 EGC31594.1 - 1 9.8 6.4 0.54 10.7 1.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4472) Synaptobrevin PF00957.16 EGC31594.1 - 4.9 6.8 11.7 0.23 11.0 3.7 2.0 2 1 0 2 2 2 0 Synaptobrevin DUF16 PF01519.11 EGC31594.1 - 5.6 7.2 9.1 2.8 8.2 4.3 1.9 1 1 1 2 2 2 0 Protein of unknown function DUF16 Adaptin_binding PF10199.4 EGC31594.1 - 7.7 6.8 11.3 2.4e+02 1.9 6.2 2.9 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 MFS_1 PF07690.11 EGC31595.1 - 8.2e-39 133.3 27.5 7.8e-34 116.9 8.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC31595.1 - 1.9e-16 59.7 25.4 4.6e-16 58.4 17.6 1.6 1 1 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGC31595.1 - 1.3e-05 23.8 18.3 2.2e-05 23.0 2.7 3.0 1 1 1 3 3 3 2 MFS/sugar transport protein DUF3169 PF11368.3 EGC31595.1 - 0.00039 19.6 5.9 0.0038 16.4 1.8 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF3169) TIM21 PF08294.6 EGC31595.1 - 4.8 6.8 8.1 25 4.5 0.1 4.0 5 0 0 5 5 5 0 TIM21 DUF1394 PF07159.7 EGC31596.1 - 1.9e-145 483.6 0.6 2.3e-145 483.4 0.4 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1394) Ribosomal_S24e PF01282.14 EGC31596.1 - 0.18 11.5 0.5 0.68 9.7 0.1 2.1 2 0 0 2 2 2 0 Ribosomal protein S24e DIL PF01843.14 EGC31597.1 - 2.1e-17 62.9 0.4 3.7e-17 62.1 0.3 1.4 1 0 0 1 1 1 1 DIL domain ketoacyl-synt PF00109.21 EGC31599.1 - 1.1e-68 231.5 0.0 1.6e-68 230.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC31599.1 - 2.3e-53 181.5 0.0 4.2e-53 180.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC31599.1 - 3.2e-44 150.7 0.0 5.7e-44 149.9 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC31599.1 - 3.6e-30 104.2 0.0 1e-29 102.7 0.0 1.9 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC31599.1 - 7.4e-20 71.3 0.0 2.3e-15 56.7 0.0 3.3 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 EGC31599.1 - 8.9e-18 64.7 0.0 3.3e-11 43.3 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 EGC31599.1 - 2.8e-13 49.6 0.0 4.6e-13 48.9 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGC31599.1 - 1.7e-09 37.4 0.0 6.8e-09 35.4 0.0 2.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC31599.1 - 1.7e-09 38.6 0.0 5.8e-09 36.9 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC31599.1 - 3.7e-09 36.3 0.4 9.9e-09 34.9 0.1 1.8 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 EGC31599.1 - 3.3e-08 33.8 0.0 2.4e-07 31.1 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGC31599.1 - 7.9e-08 31.9 0.0 7.5e-07 28.7 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase NAD_binding_10 PF13460.1 EGC31599.1 - 1.3e-05 25.2 0.0 0.0055 16.7 0.0 3.5 2 1 0 2 2 2 1 NADH(P)-binding PP-binding PF00550.20 EGC31599.1 - 5.9e-05 23.2 0.0 0.00026 21.1 0.0 2.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC31599.1 - 0.00081 18.4 0.4 0.0022 16.9 0.0 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC31599.1 - 0.0015 19.0 0.0 0.02 15.4 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC31599.1 - 0.0026 17.4 0.0 0.0069 16.1 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC31599.1 - 0.066 13.7 0.0 2 8.9 0.0 3.4 3 0 0 3 3 3 0 Methyltransferase domain PIP5K PF01504.13 EGC31600.1 - 6.8e-61 205.5 8.6 1.5e-60 204.4 6.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase Homeobox_KN PF05920.6 EGC31601.1 - 1.7e-17 62.7 1.1 2.8e-17 62.1 0.8 1.4 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGC31601.1 - 9.4e-09 34.7 0.3 1.5e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Homeobox domain DUF3384 PF11864.3 EGC31602.1 - 1.7e-129 432.2 52.7 7.4e-106 354.3 10.2 9.4 7 4 2 9 9 9 2 Domain of unknown function (DUF3384) Rap_GAP PF02145.10 EGC31602.1 - 5.2e-66 221.6 1.6 5.2e-66 221.6 1.1 3.2 3 0 0 3 3 3 1 Rap/ran-GAP DUF3024 PF11225.3 EGC31602.1 - 0.26 11.2 0.1 0.85 9.5 0.1 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3024) Acetyltransf_7 PF13508.1 EGC31603.1 - 1.1e-08 35.1 0.1 1.5e-08 34.6 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC31603.1 - 5.7e-06 26.2 0.0 7.7e-06 25.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC31603.1 - 0.00046 20.2 0.0 0.0006 19.9 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3579 PF12112.3 EGC31603.1 - 0.034 14.0 0.2 0.087 12.7 0.2 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3579) DUF3510 PF12022.3 EGC31604.1 - 1.8e-32 112.0 1.3 1.8e-32 112.0 0.9 4.4 5 0 0 5 5 5 1 Domain of unknown function (DUF3510) COG2 PF06148.6 EGC31604.1 - 1.8e-32 111.9 7.2 1.8e-32 111.9 5.0 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Zn_ribbon_2 PF12674.2 EGC31604.1 - 0.45 10.8 3.9 0.27 11.5 0.1 2.7 2 0 0 2 2 2 0 Putative zinc ribbon domain RabGAP-TBC PF00566.13 EGC31605.1 - 2.9e-23 82.4 0.2 2.9e-23 82.4 0.1 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain ISK_Channel PF02060.10 EGC31606.1 - 0.038 13.5 0.0 0.08 12.5 0.0 1.5 1 1 1 2 2 2 0 Slow voltage-gated potassium channel DUF2207 PF09972.4 EGC31606.1 - 0.051 12.1 0.8 0.056 12.0 0.6 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2254 PF10011.4 EGC31606.1 - 0.08 11.3 4.7 0.098 11.1 3.3 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) DUF872 PF05915.7 EGC31606.1 - 6.9 6.5 6.9 11 5.9 3.3 2.5 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Phage_holin_1 PF04531.8 EGC31606.1 - 8.8 6.4 7.3 4.5 7.4 2.0 2.3 2 1 0 2 2 2 0 Bacteriophage holin WD40 PF00400.27 EGC31607.1 - 5.7e-05 22.8 0.1 0.088 12.7 0.0 3.6 3 0 0 3 3 3 2 WD domain, G-beta repeat COQ7 PF03232.8 EGC31609.1 - 9.8e-75 249.7 0.1 1.2e-74 249.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquinone biosynthesis protein COQ7 Rubrerythrin PF02915.12 EGC31609.1 - 0.00046 20.5 1.7 0.0012 19.1 0.8 2.1 1 1 0 1 1 1 1 Rubrerythrin Colicin_immun PF09204.5 EGC31609.1 - 0.028 14.4 0.1 0.066 13.3 0.1 1.6 1 0 0 1 1 1 0 Bacterial self-protective colicin-like immunity Ferritin_2 PF13668.1 EGC31609.1 - 0.064 13.2 0.4 0.46 10.4 0.2 2.1 1 1 0 1 1 1 0 Ferritin-like domain R_equi_Vir PF05526.6 EGC31610.1 - 0.062 12.9 0.2 0.11 12.1 0.1 1.3 1 0 0 1 1 1 0 Rhodococcus equi virulence-associated protein NB PF04159.8 EGC31610.1 - 0.16 11.7 2.0 4.7 7.0 0.0 2.7 3 0 0 3 3 3 0 NB glycoprotein Pneumo_phosprot PF02478.11 EGC31610.1 - 0.49 9.8 9.0 0.73 9.3 6.2 1.2 1 0 0 1 1 1 0 Pneumovirus phosphoprotein Erf4 PF10256.4 EGC31611.1 - 0.0011 18.8 2.7 0.0053 16.6 1.8 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4293 PF14126.1 EGC31611.1 - 0.014 15.3 4.9 0.019 14.8 3.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4293) DUF4131 PF13567.1 EGC31611.1 - 0.047 13.0 0.3 0.066 12.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Mem_trans PF03547.13 EGC31611.1 - 0.067 11.4 5.7 0.092 11.0 3.9 1.1 1 0 0 1 1 1 0 Membrane transport protein VIT1 PF01988.14 EGC31611.1 - 0.35 10.3 2.5 0.45 9.9 1.7 1.1 1 0 0 1 1 1 0 VIT family DUF2207 PF09972.4 EGC31611.1 - 0.54 8.7 3.9 0.76 8.2 2.7 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) CRT10 PF08728.5 EGC31612.1 - 0.098 10.6 21.7 0.11 10.4 15.1 1.2 1 0 0 1 1 1 0 CRT10 MIP-T3 PF10243.4 EGC31612.1 - 0.17 10.3 76.0 0.29 9.5 52.7 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EGC31612.1 - 0.58 8.5 48.0 0.88 7.9 33.3 1.3 1 0 0 1 1 1 0 Daxx Family VWA_2 PF13519.1 EGC31613.1 - 5.9e-13 49.2 0.3 3.6e-12 46.7 0.0 2.3 2 0 0 2 2 2 1 von Willebrand factor type A domain Sec23_BS PF08033.7 EGC31613.1 - 0.001 19.5 0.7 0.0043 17.5 0.1 2.5 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Sec23_trunk PF04811.10 EGC31613.1 - 0.0044 16.4 0.6 1.5 8.1 0.0 3.0 2 1 1 3 3 3 2 Sec23/Sec24 trunk domain zf-Sec23_Sec24 PF04810.10 EGC31613.1 - 0.017 14.6 0.7 0.093 12.3 0.1 2.1 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger VWA_CoxE PF05762.9 EGC31613.1 - 0.19 10.8 0.7 2.2 7.3 0.0 2.5 3 0 0 3 3 3 0 VWA domain containing CoxE-like protein RNA_pol_Rbc25 PF08292.7 EGC31613.1 - 0.43 10.7 3.2 0.37 10.9 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase III subunit Rpc25 cobW PF02492.14 EGC31614.1 - 9.8e-07 28.3 1.1 0.088 12.2 0.0 3.1 3 0 0 3 3 3 2 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGC31614.1 - 1e-05 25.1 0.0 2.8e-05 23.7 0.0 1.8 2 0 0 2 2 2 1 Cobalamin synthesis protein cobW C-terminal domain AAA_22 PF13401.1 EGC31614.1 - 0.008 16.3 0.8 0.2 11.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF2201_N PF13203.1 EGC31614.1 - 0.06 12.5 0.9 0.09 11.9 0.6 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain BNIP3 PF06553.7 EGC31614.1 - 0.066 12.5 2.1 0.11 11.8 1.5 1.3 1 0 0 1 1 1 0 BNIP3 VESA1_N PF12785.2 EGC31614.1 - 0.26 10.2 11.7 0.37 9.6 8.1 1.1 1 0 0 1 1 1 0 Variant erythrocyte surface antigen-1 zf-RING_2 PF13639.1 EGC31615.1 - 6.4e-16 57.9 6.4 7.9e-16 57.6 4.5 1.1 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC31615.1 - 5.7e-08 32.7 9.7 1.4e-07 31.4 6.7 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC31615.1 - 3e-07 30.0 2.8 4e-07 29.6 2.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31615.1 - 3.1e-07 29.9 5.9 4.5e-07 29.4 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31615.1 - 5.1e-07 29.6 6.3 7.2e-07 29.1 4.4 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31615.1 - 3.2e-06 26.7 3.1 4.3e-06 26.3 2.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC31615.1 - 3.2e-05 23.6 4.0 7.1e-05 22.5 2.7 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_1 PF14446.1 EGC31615.1 - 5.2e-05 22.8 4.6 0.0013 18.4 0.8 2.2 2 0 0 2 2 2 1 Prokaryotic RING finger family 1 zf-RING-like PF08746.6 EGC31615.1 - 0.021 14.7 2.5 0.037 14.0 1.7 1.4 1 1 0 1 1 1 0 RING-like domain Rad50_zn_hook PF04423.9 EGC31615.1 - 0.033 13.6 2.2 0.074 12.5 0.0 2.3 2 1 0 2 2 2 0 Rad50 zinc hook motif Vps39_2 PF10367.4 EGC31615.1 - 0.041 14.0 0.9 0.22 11.6 0.1 1.9 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 DUF2256 PF10013.4 EGC31615.1 - 0.046 13.4 0.9 0.38 10.5 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2256) DUF2225 PF09986.4 EGC31615.1 - 0.058 12.8 0.4 8.1 5.8 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2225) zf-RING_4 PF14570.1 EGC31615.1 - 0.069 12.7 7.0 0.44 10.1 5.2 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zinc-ribbons_6 PF07191.7 EGC31615.1 - 0.26 11.1 3.8 4.6 7.1 0.1 2.4 1 1 1 2 2 2 0 zinc-ribbons RINGv PF12906.2 EGC31615.1 - 0.35 10.9 5.6 1.1 9.3 3.8 1.8 1 1 0 1 1 1 0 RING-variant domain zf-RING_UBOX PF13445.1 EGC31615.1 - 0.39 10.4 3.7 6.3 6.5 0.2 2.8 2 1 1 3 3 3 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC31615.1 - 0.5 10.2 6.1 1.7 8.5 4.3 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGC31615.1 - 0.84 9.6 6.9 8.3 6.4 4.8 2.4 1 1 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EGC31615.1 - 0.87 9.1 6.5 2.7 7.6 4.5 2.0 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 PHD PF00628.24 EGC31615.1 - 1.2 8.8 8.6 4 7.1 6.0 2.0 1 1 0 1 1 1 0 PHD-finger zf-Nse PF11789.3 EGC31615.1 - 1.6 8.3 6.4 2.6 7.6 4.5 1.5 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit LIM PF00412.17 EGC31615.1 - 1.7 8.7 6.6 22 5.2 0.5 2.6 1 1 1 2 2 2 0 LIM domain DUF2175 PF09943.4 EGC31615.1 - 2.8 8.0 5.1 0.9 9.6 1.1 2.0 1 1 1 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2175) C1_1 PF00130.17 EGC31615.1 - 4.1 7.2 7.3 64 3.3 5.0 2.5 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Gaa1 PF04114.9 EGC31617.1 - 1.5e-58 198.7 21.2 9.6e-49 166.4 2.1 3.6 3 1 0 3 3 3 3 Gaa1-like, GPI transamidase component DUF1152 PF06626.7 EGC31617.1 - 0.081 12.0 0.0 0.13 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1152) Tmemb_9 PF05434.6 EGC31617.1 - 0.12 12.1 0.3 3.1 7.5 0.2 2.5 2 0 0 2 2 2 0 TMEM9 ADP_PFK_GK PF04587.10 EGC31620.1 - 2.3e-72 243.6 0.0 3e-72 243.2 0.0 1.1 1 0 0 1 1 1 1 ADP-specific Phosphofructokinase/Glucokinase conserved region ETRAMP PF09716.5 EGC31620.1 - 7.2 6.6 7.4 1.5 8.7 0.6 2.5 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) FH2 PF02181.18 EGC31621.1 - 1.1e-81 274.5 10.6 1.4e-81 274.2 7.3 1.1 1 0 0 1 1 1 1 Formin Homology 2 Domain 3Beta_HSD PF01073.14 EGC31623.1 - 1.1e-11 43.9 0.0 1.5e-11 43.5 0.0 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC31623.1 - 2.2e-10 40.4 0.0 4.6e-10 39.3 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGC31623.1 - 2.3e-09 36.5 0.0 5.2e-09 35.3 0.0 1.6 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGC31623.1 - 0.00081 18.3 0.0 0.0016 17.4 0.0 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGC31623.1 - 0.0011 19.0 0.0 0.13 12.2 0.0 2.3 2 0 0 2 2 2 1 NADH(P)-binding NmrA PF05368.8 EGC31623.1 - 0.029 13.6 0.0 0.089 12.0 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family UPF0203 PF05254.7 EGC31624.1 - 2.9e-19 68.6 5.4 3.7e-19 68.3 3.8 1.1 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0203) Cmc1 PF08583.5 EGC31624.1 - 0.014 15.1 3.4 1.8 8.4 0.2 2.1 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like COX6B PF02297.12 EGC31624.1 - 0.02 14.8 7.4 0.2 11.6 0.9 2.0 1 1 1 2 2 2 0 Cytochrome oxidase c subunit VIb RINGv PF12906.2 EGC31624.1 - 0.087 12.8 2.2 0.24 11.4 1.6 1.9 1 1 0 1 1 1 0 RING-variant domain CHCH PF06747.8 EGC31624.1 - 0.62 10.0 3.4 0.46 10.4 0.2 2.1 2 0 0 2 2 2 0 CHCH domain BEN PF10523.4 EGC31624.1 - 1.2 9.2 4.6 5.5 7.1 3.2 1.9 1 1 0 1 1 1 0 BEN domain Citrate_synt PF00285.16 EGC31625.1 - 3.3e-115 384.6 0.0 3.7e-115 384.4 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase DSS1_SEM1 PF05160.8 EGC31626.1 - 8.4e-15 54.3 21.6 8.4e-15 54.3 15.0 1.5 1 1 0 1 1 1 1 DSS1/SEM1 family UPF0193 PF05250.6 EGC31626.1 - 1.2 8.7 4.2 1.2 8.6 2.9 1.2 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0193) EGF_2 PF07974.8 EGC31628.1 - 0.24 11.5 7.3 0.46 10.6 5.1 1.5 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.7 EGC31629.1 - 4.5e-181 586.6 71.6 9.6e-17 60.6 0.3 14.5 13 1 2 15 15 15 15 FNIP Repeat DUF1769 PF08588.5 EGC31629.1 - 8.9e-08 31.9 43.6 2 8.4 0.1 15.3 4 3 15 19 19 19 5 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC31629.1 - 1.1e-05 25.3 0.0 11 5.9 0.0 7.2 6 3 3 9 9 9 2 Phage minor tail protein MerC PF03203.9 EGC31629.1 - 0.026 14.8 0.0 53 4.2 0.0 5.2 5 1 1 6 6 6 0 MerC mercury resistance protein DUF3215 PF11503.3 EGC31629.1 - 0.028 14.0 0.2 1.2 8.7 0.0 3.8 3 1 1 4 4 4 0 Protein of unknown function (DUF3215) F-box-like_2 PF13013.1 EGC31629.1 - 0.1 12.3 0.3 68 3.2 0.0 4.1 4 0 0 4 4 4 0 F-box-like domain Myb_DNA-binding PF00249.26 EGC31631.1 - 4.9e-11 42.5 0.1 8.7e-11 41.7 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC31631.1 - 3.6e-06 26.9 0.2 3.6e-06 26.9 0.1 2.4 3 0 0 3 3 3 1 Myb-like DNA-binding domain DNA_pack_N PF02500.10 EGC31631.1 - 0.014 14.9 2.0 0.027 13.9 0.1 2.3 2 0 0 2 2 2 0 Probable DNA packing protein, N-terminus DUF3452 PF11934.3 EGC31631.1 - 1.3 8.3 9.1 0.067 12.5 0.7 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3452) Sedlin_N PF04628.8 EGC31632.1 - 1.2e-45 154.5 2.5 1.4e-45 154.3 1.7 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGC31632.1 - 1.6e-09 37.5 1.0 2.8e-07 30.3 0.2 2.1 2 0 0 2 2 2 2 Sybindin-like family Tmemb_185A PF10269.4 EGC31634.1 - 8.2e-16 58.3 50.7 1.4e-07 31.3 15.6 3.4 1 1 2 3 3 3 3 Transmembrane Fragile-X-F protein F-box-like PF12937.2 EGC31634.1 - 0.0088 15.7 0.0 0.028 14.1 0.0 1.9 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC31634.1 - 0.018 14.6 0.2 0.042 13.5 0.1 1.7 1 0 0 1 1 1 0 F-box domain Y_phosphatase PF00102.22 EGC31635.1 - 1.2e-72 244.0 1.3 2.8e-72 242.8 0.0 2.1 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGC31635.1 - 8.3e-05 22.1 0.0 8.3e-05 22.1 0.0 3.0 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGC31635.1 - 0.032 14.2 0.1 1.1 9.3 0.0 2.8 3 0 0 3 3 3 0 Inositol hexakisphosphate EGF_2 PF07974.8 EGC31636.1 - 3e-10 40.0 65.0 5.1e-05 23.3 7.9 4.5 4 0 0 4 4 4 4 EGF-like domain TIG PF01833.19 EGC31636.1 - 6.4e-05 22.8 20.8 0.012 15.5 1.0 4.1 3 0 0 3 3 3 2 IPT/TIG domain Laminin_EGF PF00053.19 EGC31636.1 - 9.9 6.1 50.1 6.4 6.7 5.7 4.5 3 1 1 4 4 4 0 Laminin EGF-like (Domains III and V) Ras PF00071.17 EGC31637.1 - 2.9e-59 199.0 0.0 3.4e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31637.1 - 6e-21 75.1 0.0 8.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC31637.1 - 7.8e-18 64.3 0.0 1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC31637.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC31637.1 - 1.8e-06 27.4 0.0 1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC31637.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EGC31637.1 - 2.4e-05 23.9 0.0 0.0028 17.2 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EGC31637.1 - 0.0028 16.8 0.0 0.0048 16.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGC31637.1 - 0.0085 15.3 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC31637.1 - 0.024 14.1 0.0 0.3 10.5 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGC31637.1 - 0.092 12.7 0.2 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 EGC31637.1 - 0.11 11.2 0.1 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein Y_phosphatase2 PF03162.8 EGC31638.1 - 9.6e-57 190.9 0.0 1e-56 190.8 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGC31638.1 - 0.00036 20.8 0.0 0.0046 17.2 0.0 1.9 1 1 1 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGC31638.1 - 0.046 13.0 0.0 0.053 12.8 0.0 1.1 1 0 0 1 1 1 0 Protein-tyrosine phosphatase DSPc PF00782.15 EGC31638.1 - 0.088 12.3 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain LSM PF01423.17 EGC31640.1 - 6.3e-20 70.5 0.2 7.1e-20 70.3 0.1 1.0 1 0 0 1 1 1 1 LSM domain Abhydrolase_6 PF12697.2 EGC31641.1 - 4.2e-19 69.3 0.0 5.9e-19 68.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC31641.1 - 8.5e-13 48.3 0.0 1.2e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC31641.1 - 4e-10 39.6 0.0 3e-09 36.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGC31641.1 - 0.0016 18.2 0.2 0.038 13.7 0.1 2.2 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EGC31641.1 - 0.06 12.7 0.0 4.9 6.5 0.0 2.4 2 1 0 2 2 2 0 Serine hydrolase (FSH1) MCM PF00493.18 EGC31643.1 - 5e-132 439.6 0.0 1.2e-131 438.4 0.0 1.6 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGC31643.1 - 2.4e-15 57.0 2.3 2.4e-15 57.0 1.6 2.8 2 1 0 2 2 2 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC31643.1 - 3.3e-11 42.7 0.0 2.4e-08 33.4 0.0 3.2 2 1 1 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGC31643.1 - 8.1e-05 22.2 0.0 0.00018 21.1 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC31643.1 - 0.00012 21.8 0.0 0.00037 20.2 0.0 1.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGC31643.1 - 0.0036 16.8 0.0 0.0085 15.5 0.0 1.7 1 1 0 1 1 1 1 Sigma-54 interaction domain TPP_enzyme_N PF02776.13 EGC31644.1 - 5.3e-42 143.2 0.0 1.7e-41 141.5 0.0 1.8 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGC31644.1 - 9.5e-31 106.3 0.0 1.6e-30 105.6 0.0 1.4 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain TPP_enzyme_C PF02775.16 EGC31644.1 - 2.3e-24 85.7 0.0 4.6e-22 78.2 0.0 2.8 4 0 0 4 4 4 2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TILa PF12714.2 EGC31646.1 - 0.23 11.2 52.9 2.3 8.0 2.7 6.6 4 2 2 6 6 6 0 TILa domain DUF1754 PF08555.5 EGC31648.1 - 0.012 16.1 1.8 0.021 15.3 1.2 1.4 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) AMP-binding PF00501.23 EGC31649.1 - 0.063 11.6 0.0 0.07 11.5 0.0 1.1 1 0 0 1 1 1 0 AMP-binding enzyme AMP-binding PF00501.23 EGC31650.1 - 2.8e-67 226.9 0.0 3.6e-67 226.5 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC31650.1 - 1.8e-13 51.2 0.0 2.9e-13 50.5 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Citrate_synt PF00285.16 EGC31651.1 - 0.0012 17.6 2.2 0.002 16.9 1.5 1.4 1 1 0 1 1 1 1 Citrate synthase SPT16 PF08644.6 EGC31651.1 - 0.0085 15.9 6.1 0.011 15.6 4.2 1.2 1 0 0 1 1 1 1 FACT complex subunit (SPT16/CDC68) Cauli_AT PF03233.8 EGC31651.1 - 0.0091 15.7 2.0 0.012 15.3 1.4 1.2 1 0 0 1 1 1 1 Aphid transmission protein FimP PF09766.4 EGC31651.1 - 0.015 14.3 15.8 0.017 14.2 11.0 1.1 1 0 0 1 1 1 0 Fms-interacting protein APG6 PF04111.7 EGC31651.1 - 0.029 13.4 11.1 0.039 13.0 7.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Kei1 PF08552.6 EGC31651.1 - 0.043 13.4 3.1 0.054 13.1 2.1 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Peptidase_S15 PF02129.13 EGC31651.1 - 0.077 12.3 3.0 0.089 12.2 2.1 1.2 1 0 0 1 1 1 0 X-Pro dipeptidyl-peptidase (S15 family) DUF4557 PF15101.1 EGC31651.1 - 0.087 12.6 12.7 0.095 12.5 8.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DDHD PF02862.12 EGC31651.1 - 0.09 12.5 5.7 0.11 12.3 4.0 1.1 1 0 0 1 1 1 0 DDHD domain DUF4175 PF13779.1 EGC31651.1 - 0.1 10.3 25.8 0.1 10.2 17.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Mgr1 PF08602.5 EGC31651.1 - 0.12 11.3 6.9 0.13 11.2 4.8 1.1 1 0 0 1 1 1 0 Mgr1-like, i-AAA protease complex subunit Suf PF05843.9 EGC31651.1 - 0.13 11.9 14.4 0.14 11.8 10.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) TFIIA PF03153.8 EGC31651.1 - 0.13 12.1 19.5 0.13 12.0 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Allexi_40kDa PF05549.6 EGC31651.1 - 0.16 11.2 6.4 0.2 10.9 4.4 1.1 1 0 0 1 1 1 0 Allexivirus 40kDa protein IncA PF04156.9 EGC31651.1 - 0.2 11.2 11.7 0.24 10.9 8.1 1.2 1 0 0 1 1 1 0 IncA protein DUF1840 PF08895.6 EGC31651.1 - 0.22 11.5 8.1 0.3 11.1 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1840) DUF3414 PF11894.3 EGC31651.1 - 0.32 7.8 11.1 0.36 7.6 7.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3414) DUF1669 PF07894.7 EGC31651.1 - 0.37 9.9 5.4 0.46 9.6 3.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) AAA_23 PF13476.1 EGC31651.1 - 0.44 10.8 14.8 0.53 10.5 10.2 1.1 1 0 0 1 1 1 0 AAA domain HGTP_anticodon2 PF12745.2 EGC31651.1 - 0.46 9.5 10.0 0.59 9.2 6.9 1.1 1 0 0 1 1 1 0 Anticodon binding domain of tRNAs RapA_C PF12137.3 EGC31651.1 - 0.56 8.9 14.4 3.3 6.4 10.4 1.7 2 0 0 2 2 2 0 RNA polymerase recycling family C-terminal UPF0560 PF10577.4 EGC31651.1 - 0.68 8.1 10.9 0.66 8.1 7.5 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 Activator_LAG-3 PF11498.3 EGC31651.1 - 0.84 8.3 37.2 1.2 7.8 25.8 1.3 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.9 EGC31651.1 - 1.1 8.8 5.7 1.4 8.4 3.9 1.1 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus Serinc PF03348.10 EGC31651.1 - 1.2 7.7 6.0 1.2 7.7 4.2 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) PAT1 PF09770.4 EGC31651.1 - 1.5 6.9 34.7 1.5 6.9 24.1 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 EGC31651.1 - 1.9 7.9 9.9 2.2 7.7 6.9 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain V_ATPase_I PF01496.14 EGC31651.1 - 2.1 6.1 7.7 2.3 5.9 5.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Peptidase_S49_N PF08496.5 EGC31651.1 - 2.4 7.9 7.6 3.1 7.5 5.3 1.1 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1925 PF09094.6 EGC31651.1 - 2.4 8.1 6.9 3.9 7.5 4.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1925) ZYG-11_interact PF05884.7 EGC31651.1 - 3 6.8 8.2 3.9 6.4 5.7 1.3 1 0 0 1 1 1 0 Interactor of ZYG-11 FlaG PF03646.10 EGC31651.1 - 3.3 7.9 21.0 5 7.3 14.5 1.3 1 0 0 1 1 1 0 FlaG protein TMPIT PF07851.8 EGC31651.1 - 3.5 6.5 10.9 4.8 6.1 7.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3595 PF12166.3 EGC31651.1 - 3.7 6.2 12.8 5 5.8 8.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) Folliculin PF11704.3 EGC31651.1 - 3.8 7.0 8.9 5.2 6.6 6.2 1.2 1 0 0 1 1 1 0 Vesicle coat protein involved in Golgi to plasma membrane transport Pex16 PF08610.5 EGC31651.1 - 4.2 6.2 9.7 5.2 5.9 6.7 1.2 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF3464 PF11947.3 EGC31651.1 - 4.8 6.6 9.1 6.7 6.1 6.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) CPSF100_C PF13299.1 EGC31651.1 - 5.2 7.2 9.8 6.3 6.9 6.8 1.2 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF2547 PF10818.3 EGC31651.1 - 5.6 7.6 26.1 2.6 8.7 16.5 1.7 2 0 0 2 2 1 0 Protein of unknown function (DUF2547) Tweety PF04906.8 EGC31651.1 - 6 5.1 7.1 8 4.7 4.9 1.2 1 0 0 1 1 1 0 Tweety Shisa PF13908.1 EGC31651.1 - 7.5 6.6 19.3 10 6.2 13.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF1517 PF07466.6 EGC31652.1 - 0.046 12.7 4.7 2.2 7.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1517) B3_4 PF03483.12 EGC31656.1 - 1.5e-24 86.4 0.1 2.9e-24 85.4 0.1 1.5 1 0 0 1 1 1 1 B3/4 domain B5 PF03484.10 EGC31656.1 - 1.7e-18 66.1 0.3 2e-17 62.7 0.0 2.5 2 0 0 2 2 2 1 tRNA synthetase B5 domain DUF162 PF02589.10 EGC31657.1 - 1.3e-24 86.7 0.2 1.5e-24 86.5 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised ACR, YkgG family COG1556 Polysacc_synt_2 PF02719.10 EGC31657.1 - 0.17 10.7 3.9 0.15 10.9 0.2 2.4 2 1 1 3 3 3 0 Polysaccharide biosynthesis protein SAP PF02037.22 EGC31658.1 - 1.1e-08 34.4 0.0 3.4e-08 32.7 0.0 2.0 1 0 0 1 1 1 1 SAP domain S-antigen PF05756.6 EGC31658.1 - 4.7 7.2 8.5 1.4 8.9 1.7 2.6 3 0 0 3 3 3 0 S-antigen protein EF-hand_6 PF13405.1 EGC31659.1 - 6e-11 41.2 0.3 0.13 12.2 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EGC31659.1 - 1.8e-09 36.2 1.3 0.024 13.9 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EGC31659.1 - 1e-08 35.1 3.0 4.3e-05 23.5 0.4 3.2 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC31659.1 - 1.1e-05 24.9 0.2 0.31 10.6 0.0 3.8 4 0 0 4 4 4 2 EF-hand domain pair TTL PF03133.10 EGC31659.1 - 0.0089 14.9 0.2 0.01 14.8 0.1 1.2 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family SPARC_Ca_bdg PF10591.4 EGC31659.1 - 0.03 14.3 6.0 4.1 7.4 0.8 3.1 1 1 3 4 4 4 0 Secreted protein acidic and rich in cysteine Ca binding region Sigma70_r1_1 PF03979.9 EGC31659.1 - 0.068 13.1 0.2 5.1 7.1 0.0 2.2 2 0 0 2 2 2 0 Sigma-70 factor, region 1.1 Hormone_3 PF00159.13 EGC31659.1 - 0.12 12.4 0.1 0.23 11.5 0.0 1.4 1 0 0 1 1 1 0 Pancreatic hormone peptide EF-hand_5 PF13202.1 EGC31659.1 - 0.15 11.4 1.4 10 5.6 0.0 3.2 3 0 0 3 3 3 0 EF hand Frag1 PF10277.4 EGC31660.1 - 9.6e-21 74.2 18.3 1.4e-18 67.1 8.7 2.0 1 1 1 2 2 2 2 Frag1/DRAM/Sfk1 family DUF998 PF06197.8 EGC31660.1 - 6e-05 22.4 0.6 9.3e-05 21.8 0.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF998) DUF981 PF06168.6 EGC31660.1 - 0.015 15.0 0.2 0.032 14.0 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF981) DUF2663 PF10864.3 EGC31660.1 - 0.17 12.0 4.9 0.076 13.2 1.3 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2663) Clathrin-link PF09268.5 EGC31660.1 - 0.27 10.2 1.3 0.47 9.5 0.1 2.0 2 0 0 2 2 2 0 Clathrin, heavy-chain linker PIG-F PF06699.6 EGC31660.1 - 0.41 10.5 4.4 0.65 9.9 3.0 1.3 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F DUF1129 PF06570.6 EGC31660.1 - 0.91 8.7 4.7 1.5 8.1 3.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) 7TMR-DISM_7TM PF07695.6 EGC31660.1 - 1.2 8.7 14.8 0.64 9.6 8.6 1.5 1 1 0 1 1 1 0 7TM diverse intracellular signalling PIG-P PF08510.7 EGC31660.1 - 4.4 6.9 12.6 0.75 9.4 2.4 2.8 2 1 1 3 3 3 0 PIG-P HlyIII PF03006.15 EGC31660.1 - 5.5 6.3 13.6 2.6 7.3 6.2 2.3 1 1 1 2 2 2 0 Haemolysin-III related WRW PF10206.4 EGC31661.1 - 0.069 13.2 0.1 0.075 13.0 0.1 1.1 1 0 0 1 1 1 0 Mitochondrial F1F0-ATP synthase, subunit f Solute_trans_a PF03619.11 EGC31661.1 - 0.077 12.2 0.0 0.081 12.2 0.0 1.0 1 0 0 1 1 1 0 Organic solute transporter Ostalpha Sybindin PF04099.7 EGC31661.1 - 0.1 12.2 0.1 0.15 11.7 0.0 1.3 1 1 0 1 1 1 0 Sybindin-like family Gln-synt_C PF00120.19 EGC31662.1 - 8.6e-64 215.1 0.0 1.1e-63 214.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Gln-synt_N PF03951.14 EGC31662.1 - 0.058 12.9 0.1 0.35 10.4 0.1 2.3 1 1 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain Fucokinase PF07959.7 EGC31663.1 - 1e-61 208.8 0.0 2.1e-61 207.7 0.0 1.5 1 1 0 1 1 1 1 L-fucokinase RCC1 PF00415.13 EGC31664.1 - 3.2e-37 126.4 0.0 1.7e-10 40.8 0.0 5.6 5 1 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC31664.1 - 6.2e-23 79.8 8.0 6.4e-08 32.0 0.1 4.9 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat Fe-S_biosyn PF01521.15 EGC31664.1 - 0.011 15.6 1.6 0.021 14.7 0.5 2.0 1 1 1 2 2 2 0 Iron-sulphur cluster biosynthesis DUF2758 PF10957.3 EGC31664.1 - 0.086 12.6 0.1 0.19 11.5 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2758) CBM_X PF06204.6 EGC31664.1 - 0.52 9.8 3.0 19 4.8 0.1 2.7 2 0 0 2 2 2 0 Putative carbohydrate binding domain EF-hand_1 PF00036.27 EGC31665.1 - 5.1e-20 69.1 1.4 1.1e-05 24.3 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGC31665.1 - 9.6e-16 56.2 1.9 5.7e-05 22.6 0.0 3.4 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 EGC31665.1 - 1.1e-14 54.3 1.3 1.4e-08 34.7 0.3 2.2 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC31665.1 - 1.2e-12 46.5 3.1 0.00015 20.9 0.1 3.5 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EGC31665.1 - 6.7e-10 38.4 6.3 2.4e-05 23.8 0.2 3.8 2 2 2 4 4 4 3 EF-hand domain pair Caleosin PF05042.8 EGC31665.1 - 0.00063 19.3 0.1 0.0055 16.2 0.0 2.2 2 1 0 2 2 2 1 Caleosin related protein SPARC_Ca_bdg PF10591.4 EGC31665.1 - 0.0049 16.8 0.8 0.14 12.2 0.1 2.1 2 0 0 2 2 2 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC31665.1 - 0.0053 16.3 0.6 0.8 9.4 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_9 PF14658.1 EGC31665.1 - 0.057 13.3 0.0 1.7 8.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain Glyco_transf_41 PF13844.1 EGC31666.1 - 1.6e-53 181.3 0.6 5.7e-29 100.4 0.1 2.4 2 0 0 2 2 2 2 Glycosyl transferase family 41 TPR_11 PF13414.1 EGC31666.1 - 3.5e-53 177.1 26.8 1.7e-13 49.9 0.1 5.2 1 1 6 7 7 7 7 TPR repeat TPR_1 PF00515.23 EGC31666.1 - 3.3e-47 156.2 14.7 1.2e-08 34.1 0.2 7.8 7 1 1 8 8 8 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31666.1 - 4.5e-36 119.8 2.5 1.9e-05 24.2 0.0 7.7 7 0 0 7 7 7 6 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31666.1 - 6.2e-33 110.2 20.0 0.00099 19.1 0.0 8.8 8 0 0 8 8 8 7 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31666.1 - 5.4e-28 94.6 17.3 8.8e-07 28.2 0.0 7.6 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31666.1 - 7.5e-27 93.0 5.4 7.9e-07 28.9 0.0 4.7 2 1 3 5 5 5 5 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31666.1 - 4.1e-21 73.0 0.4 0.006 16.2 0.0 7.0 7 0 0 7 7 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31666.1 - 1.7e-19 69.9 0.0 1.2e-05 25.7 0.0 4.4 2 1 1 4 4 4 4 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31666.1 - 9.2e-13 47.6 3.2 0.34 10.8 0.0 6.8 7 0 0 7 7 7 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31666.1 - 1e-12 47.4 0.0 0.12 13.0 0.0 5.4 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31666.1 - 8.3e-10 38.4 1.7 1.3 9.6 0.0 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC31666.1 - 9.9e-08 32.2 3.6 0.4 11.0 0.1 4.8 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31666.1 - 2.4e-06 27.2 0.0 0.011 15.6 0.0 3.5 2 1 1 3 3 3 1 Tetratricopeptide repeat Sel1 PF08238.7 EGC31666.1 - 1.7e-05 25.2 0.4 6.7 7.5 0.0 5.8 6 0 0 6 6 6 1 Sel1 repeat TPR_15 PF13429.1 EGC31666.1 - 0.0011 18.0 0.1 5.5 5.9 0.0 3.4 1 1 2 3 3 3 1 Tetratricopeptide repeat DUF3366 PF11846.3 EGC31666.1 - 0.0028 17.5 3.0 0.31 10.8 0.0 2.9 2 1 2 4 4 3 2 Domain of unknown function (DUF3366) EST1_DNA_bind PF10373.4 EGC31666.1 - 0.29 10.3 20.6 0.15 11.2 1.0 3.4 1 1 1 2 2 2 0 Est1 DNA/RNA binding domain PBP1_TM PF14812.1 EGC31669.1 - 0.12 12.6 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF912 PF06024.7 EGC31669.1 - 0.31 11.0 3.1 0.31 11.1 2.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 EGC31669.1 - 0.61 10.5 10.5 0.69 10.3 7.3 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain Ank_2 PF12796.2 EGC31670.1 - 4.5e-39 132.6 5.0 3e-13 49.8 0.0 3.4 1 1 3 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC31670.1 - 3.7e-23 81.4 5.2 0.00034 21.0 0.0 5.6 3 1 3 6 6 6 5 Ankyrin repeats (many copies) Ank PF00023.25 EGC31670.1 - 4e-23 80.0 5.4 9.2e-07 28.3 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EGC31670.1 - 2e-21 75.4 1.1 7.3e-07 29.2 0.0 4.9 2 2 3 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC31670.1 - 1.2e-20 71.5 5.9 0.00032 20.6 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat gag-asp_proteas PF13975.1 EGC31670.1 - 0.0022 17.7 0.4 0.14 11.9 0.0 2.4 2 0 0 2 2 2 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGC31670.1 - 0.033 14.0 0.2 11 6.0 0.0 2.5 1 1 1 2 2 2 0 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGC31670.1 - 0.081 13.4 0.2 1.3 9.5 0.0 2.3 1 1 1 2 2 2 0 Aspartyl protease Erf4 PF10256.4 EGC31671.1 - 8.7e-07 28.8 5.1 9.2e-06 25.5 3.5 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family AA_permease_2 PF13520.1 EGC31671.1 - 0.0078 14.7 4.3 0.01 14.4 3.0 1.1 1 0 0 1 1 1 1 Amino acid permease YWFCY PF14293.1 EGC31671.1 - 0.088 12.6 0.7 0.18 11.6 0.5 1.5 1 0 0 1 1 1 0 YWFCY protein DUF3142 PF11340.3 EGC31671.1 - 0.12 12.0 0.0 0.2 11.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3142) UPF0104 PF03706.8 EGC31671.1 - 0.17 11.1 4.9 0.23 10.7 3.4 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF2207 PF09972.4 EGC31671.1 - 0.21 10.1 9.5 0.012 14.2 2.4 1.7 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) Erf4 PF10256.4 EGC31672.1 - 2e-05 24.4 2.1 0.00021 21.1 0.1 2.2 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF2700 PF10912.3 EGC31672.1 - 0.03 14.3 1.1 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2700) DUF2404 PF10296.4 EGC31672.1 - 0.17 11.9 1.3 0.58 10.3 0.0 2.2 1 1 1 2 2 2 0 Putative integral membrane protein conserved region (DUF2404) Lyase_aromatic PF00221.14 EGC31673.1 - 6.7e-43 146.8 0.2 6.1e-30 104.0 0.0 2.9 3 0 0 3 3 3 3 Aromatic amino acid lyase FA_hydroxylase PF04116.8 EGC31674.1 - 1.2e-17 64.3 16.1 1.2e-17 64.3 11.1 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF814 PF05670.8 EGC31675.1 - 1.8e-23 82.2 0.4 3.8e-23 81.1 0.0 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF814) Methyltransf_31 PF13847.1 EGC31676.1 - 2.7e-14 53.0 0.9 3.2e-14 52.7 0.6 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC31676.1 - 2.1e-13 50.5 0.0 2.8e-13 50.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC31676.1 - 2.9e-10 40.7 0.0 3.8e-10 40.3 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC31676.1 - 7.8e-07 29.3 0.0 1.1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC31676.1 - 5.6e-06 26.7 0.0 7.3e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC31676.1 - 1.8e-05 24.4 0.0 2.4e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC31676.1 - 3.7e-05 23.1 0.0 4.6e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGC31676.1 - 0.00036 19.7 0.1 0.00043 19.4 0.1 1.1 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family PrmA PF06325.8 EGC31676.1 - 0.0012 18.0 0.0 0.0016 17.6 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC31676.1 - 0.0036 17.3 0.0 0.0098 15.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EGC31676.1 - 0.007 15.8 0.0 0.0095 15.3 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) Pox_MCEL PF03291.11 EGC31676.1 - 0.032 13.1 0.2 0.036 12.9 0.1 1.2 1 0 0 1 1 1 0 mRNA capping enzyme MetW PF07021.7 EGC31676.1 - 0.04 13.2 0.0 0.055 12.8 0.0 1.2 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW HNH_3 PF13392.1 EGC31677.1 - 8.8e-11 41.0 2.7 1.7e-10 40.0 1.9 1.6 1 0 0 1 1 1 1 HNH endonuclease zf-CCHC_5 PF14787.1 EGC31677.1 - 1.4e-07 30.8 0.4 8.6e-07 28.3 0.1 2.1 2 0 0 2 2 2 1 GAG-polyprotein viral zinc-finger zf-CCHC PF00098.18 EGC31677.1 - 0.0002 21.1 1.7 0.00033 20.4 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC31677.1 - 0.021 14.4 0.6 0.042 13.5 0.4 1.4 1 0 0 1 1 1 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGC31677.1 - 0.22 11.3 1.9 0.4 10.4 0.7 1.9 3 0 0 3 3 3 0 Zinc knuckle EGF_2 PF07974.8 EGC31679.1 - 0.00074 19.6 31.8 0.013 15.6 8.9 3.4 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.19 EGC31679.1 - 0.011 15.5 17.5 1.3 8.9 0.2 3.3 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC31679.1 - 0.016 15.2 2.6 0.016 15.2 1.8 4.1 4 0 0 4 4 4 0 Human growth factor-like EGF EGF PF00008.22 EGC31679.1 - 2.9 7.9 21.0 16 5.5 6.5 3.8 3 0 0 3 3 3 0 EGF-like domain OTU PF02338.14 EGC31680.1 - 1.1e-13 51.8 0.0 1.7e-13 51.2 0.0 1.2 1 0 0 1 1 1 1 OTU-like cysteine protease FNIP PF05725.7 EGC31681.1 - 1.3e-102 335.4 54.0 1.2e-13 50.7 0.3 12.4 10 2 2 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 EGC31681.1 - 9.8e-05 22.2 11.0 0.026 14.4 0.2 7.9 6 3 5 11 11 11 1 Protein of unknown function (DUF1769) Baculo_p47 PF05112.7 EGC31682.1 - 0.11 11.8 1.5 0.22 10.8 0.4 1.7 2 0 0 2 2 2 0 Baculovirus P47 protein ECH PF00378.15 EGC31684.1 - 5.2e-61 205.8 0.6 6.2e-61 205.6 0.4 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PGM_PMM_I PF02878.11 EGC31686.1 - 6e-39 132.6 0.3 8.8e-39 132.1 0.2 1.2 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_III PF02880.11 EGC31686.1 - 1.2e-28 99.4 0.0 2.1e-28 98.6 0.0 1.4 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_II PF02879.11 EGC31686.1 - 1e-13 51.5 0.0 3.2e-13 49.8 0.0 1.9 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_IV PF00408.15 EGC31686.1 - 3.5e-09 36.5 0.0 8e-09 35.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF1882 PF08966.6 EGC31686.1 - 0.17 11.8 2.3 0.61 10.0 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1882) Amino_oxidase PF01593.19 EGC31688.1 - 4.5e-62 210.5 0.0 6.1e-62 210.1 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC31688.1 - 6.3e-17 61.3 0.2 1.3e-16 60.3 0.1 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain DAO PF01266.19 EGC31688.1 - 1.7e-12 46.9 0.0 6e-08 31.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGC31688.1 - 7.6e-10 38.1 0.1 3.6e-09 35.9 0.1 2.0 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EGC31688.1 - 5.7e-07 29.7 0.2 0.00027 21.0 0.0 2.5 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC31688.1 - 1.7e-06 27.4 0.0 3.2e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGC31688.1 - 2.5e-06 26.2 0.0 2.9e-05 22.7 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGC31688.1 - 4.4e-06 25.9 0.7 8.1e-06 25.0 0.5 1.4 1 1 0 1 1 1 1 Thi4 family Pyr_redox PF00070.22 EGC31688.1 - 4.6e-06 26.9 0.1 1.3e-05 25.4 0.0 1.8 2 0 0 2 2 1 1 Pyridine nucleotide-disulphide oxidoreductase GIDA PF01134.17 EGC31688.1 - 7.1e-06 25.1 0.0 1.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Glucose inhibited division protein A Lycopene_cycl PF05834.7 EGC31688.1 - 6.7e-05 21.9 0.0 0.00037 19.5 0.0 1.9 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox_2 PF07992.9 EGC31688.1 - 8.1e-05 22.5 0.0 0.00036 20.4 0.0 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGC31688.1 - 0.00064 18.8 0.1 0.001 18.1 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain GDI PF00996.13 EGC31688.1 - 0.00089 17.6 0.4 0.01 14.1 0.0 2.5 3 0 0 3 3 3 1 GDP dissociation inhibitor AlaDh_PNT_C PF01262.16 EGC31688.1 - 0.023 14.2 0.1 0.12 11.9 0.0 1.9 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain Thioredoxin PF00085.15 EGC31688.1 - 0.16 11.6 0.2 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Thioredoxin Laminin_G_3 PF13385.1 EGC31689.1 - 1.9e-09 37.9 0.3 5.4e-09 36.4 0.0 1.9 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily CHB_HEX_C PF03174.8 EGC31689.1 - 3.3e-08 33.2 5.8 0.00015 21.5 0.3 3.5 3 0 0 3 3 3 2 Chitobiase/beta-hexosaminidase C-terminal domain Fn3_assoc PF13287.1 EGC31689.1 - 4.9e-08 32.9 4.7 5.6e-05 23.1 0.2 3.4 3 0 0 3 3 3 2 Fn3 associated F5_F8_type_C PF00754.20 EGC31689.1 - 6e-07 29.3 0.0 2.4e-06 27.3 0.0 2.0 1 0 0 1 1 1 1 F5/8 type C domain CHB_HEX_C_1 PF13290.1 EGC31689.1 - 1e-06 28.4 5.3 0.00099 18.8 0.4 3.1 2 0 0 2 2 2 2 Chitobiase/beta-hexosaminidase C-terminal domain GFA PF04828.9 EGC31691.1 - 1.1e-06 28.4 0.1 1.1e-06 28.4 0.1 2.0 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme FUR PF01475.14 EGC31691.1 - 0.0026 17.6 0.5 0.0037 17.1 0.4 1.2 1 0 0 1 1 1 1 Ferric uptake regulator family MDM31_MDM32 PF08118.6 EGC31692.1 - 1.2e-73 248.2 12.1 7.4e-27 93.9 0.3 4.2 2 2 1 3 3 3 3 Yeast mitochondrial distribution and morphology (MDM) proteins PALP PF00291.20 EGC31693.1 - 1.3e-75 254.4 0.0 1.5e-75 254.2 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme RhoGEF PF00621.15 EGC31694.1 - 6.5e-49 166.2 0.0 6.5e-49 166.2 0.0 3.1 4 0 0 4 4 4 1 RhoGEF domain PH PF00169.24 EGC31694.1 - 1.7e-07 31.3 0.2 1.7e-07 31.3 0.2 3.5 4 0 0 4 4 4 1 PH domain IQ PF00612.22 EGC31694.1 - 0.011 15.3 1.8 0.03 13.9 1.3 1.7 1 0 0 1 1 1 0 IQ calmodulin-binding motif CBS PF00571.23 EGC31695.1 - 8.6e-24 83.0 2.6 1.2e-07 31.4 0.0 4.9 5 0 0 5 5 5 4 CBS domain AA_permease_2 PF13520.1 EGC31696.1 - 6.3e-50 169.9 58.2 6.3e-50 169.9 40.3 1.6 1 1 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC31696.1 - 6e-41 140.2 46.8 6e-41 140.2 32.4 1.4 2 0 0 2 2 2 1 Amino acid permease AA_permease_C PF13906.1 EGC31696.1 - 7.5e-17 60.9 2.9 7.5e-17 60.9 2.0 3.9 3 0 0 3 3 3 1 C-terminus of AA_permease Spore_permease PF03845.8 EGC31696.1 - 0.00015 20.5 17.7 0.00015 20.5 12.3 3.3 2 2 0 2 2 2 1 Spore germination protein Lung_7-TM_R PF06814.8 EGC31697.1 - 4.5e-15 55.3 18.2 4.5e-15 55.3 12.6 2.4 2 0 0 2 2 2 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EGC31697.1 - 1.7e-05 24.1 22.2 1.7e-05 24.1 15.4 2.7 3 1 0 3 3 3 1 Rhodopsin-like GPCR transmembrane domain DUF502 PF04367.8 EGC31697.1 - 4.5 7.0 9.3 0.19 11.4 1.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF502) DUF2572 PF10833.3 EGC31698.1 - 0.4 10.0 5.6 0.48 9.7 3.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2572) Cytochrome_C554 PF13435.1 EGC31698.1 - 0.71 9.9 3.4 26 4.8 0.5 2.7 2 1 1 3 3 3 0 Cytochrome c554 and c-prime DUF229 PF02995.12 EGC31699.1 - 9.7e-44 149.6 0.6 4e-43 147.5 0.4 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF229) Sulfatase PF00884.18 EGC31699.1 - 0.0013 18.0 0.1 0.017 14.3 0.0 2.4 2 1 0 3 3 3 1 Sulfatase FNIP PF05725.7 EGC31700.1 - 2.7e-29 100.8 9.4 1.1e-10 41.3 0.1 3.4 3 0 0 3 3 3 3 FNIP Repeat Terminase_1 PF03354.10 EGC31700.1 - 0.00049 18.6 0.4 0.00066 18.2 0.2 1.1 1 0 0 1 1 1 1 Phage Terminase DUF1769 PF08588.5 EGC31700.1 - 0.0059 16.5 0.6 2.2 8.3 0.0 3.1 3 0 0 3 3 3 2 Protein of unknown function (DUF1769) DUF2513 PF10711.4 EGC31700.1 - 0.034 14.2 0.1 0.054 13.5 0.1 1.3 1 0 0 1 1 1 0 Hypothetical protein (DUF2513) GDI PF00996.13 EGC31701.1 - 0.015 13.6 0.1 0.47 8.7 0.0 2.1 2 0 0 2 2 2 0 GDP dissociation inhibitor FNIP PF05725.7 EGC31703.1 - 3.1e-186 603.1 58.6 1.3e-15 57.0 0.3 15.2 10 2 4 16 16 16 16 FNIP Repeat MerC PF03203.9 EGC31703.1 - 0.00094 19.5 0.3 1.3e+02 2.9 0.0 6.6 3 2 3 7 7 7 0 MerC mercury resistance protein Oxidored_FMN PF00724.15 EGC31705.1 - 6.5e-10 38.5 0.0 7.9e-10 38.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family RRM_1 PF00076.17 EGC31706.1 - 3e-06 26.7 0.0 6.8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31706.1 - 3.7e-06 26.8 0.0 7.3e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC31706.1 - 0.0019 17.9 0.0 0.0034 17.1 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_5 PF13893.1 EGC31706.1 - 0.033 14.0 0.0 0.061 13.1 0.0 1.4 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_16 PF10294.4 EGC31708.1 - 5.7e-18 64.9 0.0 7.8e-18 64.5 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGC31708.1 - 2.6e-06 27.1 0.1 0.017 14.7 0.0 2.3 2 0 0 2 2 2 2 Methyltransferase domain Methyltransf_23 PF13489.1 EGC31708.1 - 1.6e-05 24.7 0.0 2.4e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC31708.1 - 2.4e-05 24.8 0.0 4.2e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC31708.1 - 0.012 14.9 0.0 0.16 11.3 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGC31708.1 - 0.017 15.5 0.0 0.046 14.2 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain MRJP PF03022.11 EGC31708.1 - 0.021 14.0 0.1 0.2 10.8 0.0 2.0 2 0 0 2 2 2 0 Major royal jelly protein Methyltransf_11 PF08241.7 EGC31708.1 - 0.027 14.9 0.0 0.092 13.2 0.0 1.9 2 1 0 2 2 1 0 Methyltransferase domain GidB PF02527.10 EGC31708.1 - 0.052 12.6 0.0 0.1 11.7 0.0 1.5 1 0 0 1 1 1 0 rRNA small subunit methyltransferase G CheR PF01739.13 EGC31708.1 - 0.1 11.8 0.0 0.2 10.8 0.0 1.5 1 0 0 1 1 1 0 CheR methyltransferase, SAM binding domain PrmA PF06325.8 EGC31708.1 - 0.15 11.1 0.0 0.26 10.3 0.0 1.4 1 1 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) CLN3 PF02487.12 EGC31709.1 - 6.1e-45 153.7 22.3 8.3e-45 153.2 10.4 2.6 1 1 1 2 2 2 2 CLN3 protein HEAT PF02985.17 EGC31710.1 - 1.6e-16 58.8 0.2 0.32 11.1 0.0 8.7 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EGC31710.1 - 8.5e-13 48.3 0.0 0.1 12.8 0.0 7.2 7 1 1 8 8 8 2 HEAT repeats HEAT_EZ PF13513.1 EGC31710.1 - 6.7e-07 29.6 0.0 2.7 8.5 0.0 7.3 7 1 1 8 8 8 2 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC31710.1 - 5.3e-06 26.7 0.3 0.044 14.1 0.0 5.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region DUF2573 PF10835.3 EGC31710.1 - 0.039 14.0 0.0 0.21 11.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2573) Cohesin_HEAT PF12765.2 EGC31710.1 - 0.062 13.2 0.0 41 4.2 0.0 4.1 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion Adaptin_N PF01602.15 EGC31710.1 - 0.36 9.0 16.4 0.086 11.1 0.5 4.9 5 1 0 5 5 5 0 Adaptin N terminal region Transferase PF02458.10 EGC31711.1 - 4.5e-11 41.8 0.0 5.8e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Transferase family RasGAP PF00616.14 EGC31712.1 - 2.2e-27 96.0 3.4 2.2e-27 96.0 2.4 6.2 5 2 0 5 5 5 1 GTPase-activator protein for Ras-like GTPase VPS9 PF02204.13 EGC31712.1 - 7.2e-24 83.8 0.1 4e-23 81.4 0.1 2.5 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Zip PF02535.17 EGC31712.1 - 4.8 6.0 10.1 11 4.9 7.0 1.6 1 0 0 1 1 1 0 ZIP Zinc transporter Rgp1 PF08737.5 EGC31713.1 - 2.9e-64 217.6 36.2 3.1e-63 214.3 13.1 3.3 2 1 0 2 2 2 1 Rgp1 Macoilin PF09726.4 EGC31714.1 - 0.002 16.5 12.1 0.002 16.5 8.4 2.6 1 1 1 2 2 2 1 Transmembrane protein CIAPIN1 PF05093.8 EGC31714.1 - 0.026 14.6 3.6 0.17 11.9 2.5 2.5 1 0 0 1 1 1 0 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Otopetrin PF03189.8 EGC31714.1 - 0.027 13.4 1.0 0.037 13.0 0.7 1.3 1 0 0 1 1 1 0 Otopetrin DUF3464 PF11947.3 EGC31714.1 - 0.058 12.8 2.2 0.24 10.8 1.5 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Endonuc_Holl PF10107.4 EGC31714.1 - 0.46 10.1 7.2 1 9.0 5.0 1.5 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase ATP-synt_ab PF00006.20 EGC31715.1 - 2e-62 210.4 0.0 2.8e-62 210.0 0.0 1.2 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGC31715.1 - 3.4e-17 62.9 0.0 6.3e-17 62.0 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGC31715.1 - 7.2e-10 38.9 0.4 1.6e-09 37.7 0.3 1.7 1 0 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain HAS-barrel PF09378.5 EGC31715.1 - 0.0071 16.2 0.2 0.016 15.0 0.1 1.6 1 0 0 1 1 1 1 HAS barrel domain Arch_flagellin PF01917.11 EGC31716.1 - 0.035 13.7 12.6 0.58 9.7 0.6 2.3 2 0 0 2 2 2 0 Archaebacterial flagellin Ribosomal_L1 PF00687.16 EGC31717.1 - 7.7e-49 165.9 6.1 9.3e-49 165.7 4.2 1.0 1 0 0 1 1 1 1 Ribosomal protein L1p/L10e family HSP90 PF00183.13 EGC31718.1 - 5.3e-75 252.8 16.7 6.3e-75 252.5 3.7 2.3 2 1 1 3 3 3 2 Hsp90 protein HATPase_c_3 PF13589.1 EGC31718.1 - 7.4e-11 41.8 0.1 2.2e-10 40.3 0.0 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC31718.1 - 2.2e-06 27.3 0.5 5.9e-06 25.9 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Phage_Gp23 PF10669.4 EGC31718.1 - 0.014 15.5 0.2 0.1 12.6 0.0 2.3 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Cpn60_TCP1 PF00118.19 EGC31719.1 - 4.8e-154 513.5 0.8 5.4e-154 513.3 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Ras PF00071.17 EGC31720.1 - 1.7e-56 190.0 0.1 1.7e-56 190.0 0.1 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EGC31720.1 - 4.5e-19 69.0 2.0 3.2e-18 66.3 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC31720.1 - 8.1e-15 54.4 0.1 1.4e-14 53.7 0.1 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC31720.1 - 4e-06 26.3 0.2 4e-06 26.3 0.2 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EGC31720.1 - 4.2e-05 23.1 0.4 6.1e-05 22.6 0.2 1.3 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein MMR_HSR1 PF01926.18 EGC31720.1 - 0.0005 20.0 0.2 0.0016 18.3 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase Glycos_transf_1 PF00534.15 EGC31720.1 - 0.0057 16.1 0.0 0.0057 16.1 0.0 2.2 1 1 1 2 2 2 1 Glycosyl transferases group 1 AAA_22 PF13401.1 EGC31720.1 - 0.0058 16.7 4.1 1.4 9.1 1.0 2.7 1 1 2 3 3 3 2 AAA domain YwhD PF08741.5 EGC31720.1 - 0.11 11.9 0.2 0.11 11.9 0.1 2.1 1 1 1 2 2 2 0 YwhD family Phage_int_SAM_4 PF13495.1 EGC31720.1 - 0.35 11.2 9.3 0.85 9.9 6.5 1.7 1 1 0 1 1 1 0 Phage integrase, N-terminal SAM-like domain AAA_23 PF13476.1 EGC31720.1 - 1.8 8.8 14.4 3 8.1 10.0 1.4 1 1 0 1 1 1 0 AAA domain BAF1_ABF1 PF04684.8 EGC31720.1 - 5.8 5.6 20.5 7.4 5.2 14.2 1.3 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Med15 PF09606.5 EGC31720.1 - 7 4.7 24.7 8.1 4.5 17.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Pkinase PF00069.20 EGC31721.1 - 2.2e-75 253.1 0.1 2.9e-75 252.7 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31721.1 - 2.9e-37 128.1 0.0 4.4e-37 127.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC31721.1 - 4.1e-07 29.2 0.0 1.4e-05 24.1 0.0 2.3 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGC31721.1 - 0.00019 20.8 0.6 0.00046 19.5 0.4 1.6 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EGC31721.1 - 0.0017 18.1 0.1 0.0026 17.5 0.1 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Pkinase_C PF00433.19 EGC31721.1 - 0.0061 17.0 1.4 0.0061 17.0 1.0 2.6 2 1 0 2 2 2 1 Protein kinase C terminal domain Kdo PF06293.9 EGC31721.1 - 0.032 13.2 0.1 0.051 12.6 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC31721.1 - 0.11 11.8 0.1 0.73 9.1 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Cpn60_TCP1 PF00118.19 EGC31722.1 - 1e-153 512.4 0.7 1.2e-153 512.2 0.5 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family COesterase PF00135.23 EGC31723.1 - 2e-19 69.7 3.1 2.2e-19 69.5 2.2 1.0 1 0 0 1 1 1 1 Carboxylesterase family Clathrin_lg_ch PF01086.12 EGC31724.1 - 1.3e-22 80.8 13.2 1.4e-22 80.7 9.1 1.1 1 0 0 1 1 1 1 Clathrin light chain RsbU_N PF08673.5 EGC31724.1 - 0.21 11.6 1.1 1.4 8.9 0.0 2.2 2 0 0 2 2 2 0 Phosphoserine phosphatase RsbU, N-terminal domain SR-25 PF10500.4 EGC31724.1 - 0.34 10.3 11.8 0.45 9.9 8.2 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CesA PF11439.3 EGC31724.1 - 0.53 10.2 5.6 0.32 10.9 1.8 2.0 2 0 0 2 2 2 0 Type III secretion system filament chaperone CesA TerD PF02342.13 EGC31726.1 - 3.9e-56 189.3 0.0 4.8e-56 189.0 0.0 1.0 1 0 0 1 1 1 1 TerD domain Ammonium_transp PF00909.16 EGC31727.1 - 2.3e-108 362.2 27.2 2.6e-108 362.0 18.9 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family Fig1 PF12351.3 EGC31728.1 - 0.001 18.9 1.8 0.001 18.9 1.2 2.7 1 1 1 3 3 3 1 Ca2+ regulator and membrane fusion protein Fig1 DUF2569 PF10754.4 EGC31728.1 - 2 8.6 25.3 0.089 12.9 7.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) PfkB PF00294.19 EGC31730.1 - 0.057 12.5 1.1 0.055 12.5 0.7 1.1 1 0 0 1 1 1 0 pfkB family carbohydrate kinase DNase_II PF03265.10 EGC31731.1 - 2.1e-25 89.4 24.4 4e-16 58.9 8.4 3.8 2 1 1 3 3 3 3 Deoxyribonuclease II Vps52 PF04129.7 EGC31732.1 - 4.2e-68 230.1 27.3 2.5e-66 224.2 18.9 2.4 1 1 0 1 1 1 1 Vps52 / Sac2 family DUF1664 PF07889.7 EGC31732.1 - 0.13 12.0 5.6 1.1 9.0 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ACCA PF03255.9 EGC31732.1 - 0.23 10.9 3.7 1.9 8.0 0.3 2.7 2 0 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit PRRSV_2b PF07069.6 EGC31732.1 - 0.54 10.5 3.1 0.87 9.9 1.0 2.2 2 0 0 2 2 2 0 Porcine reproductive and respiratory syndrome virus 2b EFG_IV PF03764.13 EGC31733.1 - 4.3e-29 100.5 0.0 1.3e-28 98.9 0.0 1.8 1 1 1 2 2 2 1 Elongation factor G, domain IV GTP_EFTU PF00009.22 EGC31733.1 - 2.3e-22 79.3 0.0 1.6e-18 66.8 0.0 2.3 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGC31733.1 - 1.1e-10 41.2 0.0 2.3e-10 40.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC31733.1 - 5.6e-07 29.5 0.0 4.2e-06 26.7 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 2 Miro PF08477.8 EGC31733.1 - 0.05 14.0 0.0 0.26 11.7 0.0 2.2 2 0 0 2 2 2 0 Miro-like protein FNIP PF05725.7 EGC31734.1 - 1.9e-11 43.7 17.2 9.4e-07 28.6 0.2 6.2 3 2 2 5 5 5 3 FNIP Repeat Ras PF00071.17 EGC31735.1 - 1.6e-59 199.9 0.0 1.8e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31735.1 - 5.1e-20 72.1 0.0 7.3e-20 71.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC31735.1 - 1.2e-09 37.7 0.0 1.4e-09 37.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC31735.1 - 1.2e-06 28.0 0.1 9.2e-06 25.2 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC31735.1 - 0.00019 21.3 0.0 0.00033 20.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EGC31735.1 - 0.0069 15.9 0.8 0.091 12.2 0.0 2.0 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein FeoB_N PF02421.13 EGC31735.1 - 0.023 13.9 0.1 0.12 11.6 0.0 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B Septin PF00735.13 EGC31735.1 - 0.028 13.4 0.0 0.061 12.3 0.0 1.6 1 0 0 1 1 1 0 Septin DUF258 PF03193.11 EGC31735.1 - 0.063 12.4 0.1 0.087 12.0 0.1 1.4 1 1 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC31735.1 - 0.069 12.5 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF2075 PF09848.4 EGC31735.1 - 0.083 11.8 0.0 0.76 8.6 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) DUF2647 PF10839.3 EGC31735.1 - 0.1 12.7 0.0 2.5 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2647) AAA_14 PF13173.1 EGC31735.1 - 0.11 12.4 0.1 0.2 11.5 0.1 1.6 1 1 0 1 1 1 0 AAA domain Glyco_transf_10 PF00852.14 EGC31736.1 - 1.7e-44 151.8 2.8 1.7e-44 151.8 2.0 2.1 2 0 0 2 2 2 1 Glycosyltransferase family 10 (fucosyltransferase) Glyco_trans_1_2 PF13524.1 EGC31736.1 - 1.8e-05 24.9 0.0 4.4e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF106 PF01956.11 EGC31736.1 - 0.04 13.4 1.3 0.076 12.5 0.9 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 UCH PF00443.24 EGC31737.1 - 1.6e-82 276.6 3.8 4.2e-82 275.2 2.7 1.8 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC31737.1 - 1.3e-24 87.2 0.1 1.4e-13 50.9 0.0 3.2 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGC31737.1 - 8.1e-14 51.8 0.0 8.1e-14 51.8 0.0 3.6 5 1 0 5 5 5 1 DUSP domain Ubiquitin_3 PF14836.1 EGC31737.1 - 0.00013 21.5 0.0 0.00034 20.2 0.0 1.7 1 0 0 1 1 1 1 Ubiquitin-like domain Mito_carr PF00153.22 EGC31738.1 - 1.8e-52 175.0 8.4 5e-21 74.2 0.4 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Peroxin-13_N PF04088.8 EGC31740.1 - 1.6 8.6 10.0 0.56 10.1 0.6 2.7 2 0 0 2 2 2 0 Peroxin 13, N-terminal region SKG6 PF08693.5 EGC31741.1 - 4.4e-08 32.3 2.8 7.9e-08 31.4 2.0 1.4 1 0 0 1 1 1 1 Transmembrane alpha-helix domain EGF_2 PF07974.8 EGC31741.1 - 0.0093 16.1 13.7 0.0093 16.1 9.5 2.9 2 0 0 2 2 2 2 EGF-like domain Phosphodiest PF01663.17 EGC31742.1 - 2.6e-71 240.8 0.1 3.6e-71 240.4 0.1 1.2 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGC31742.1 - 1.2e-07 31.2 4.2 8.2e-06 25.2 0.0 2.8 2 1 0 3 3 3 2 Sulfatase PglZ PF08665.7 EGC31742.1 - 0.00083 19.0 0.0 0.0029 17.2 0.0 1.9 1 0 0 1 1 1 1 PglZ domain CS PF04969.11 EGC31743.1 - 6.3e-06 26.6 0.0 7.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 CS domain Cytotoxic PF09000.5 EGC31743.1 - 0.051 13.5 0.1 0.067 13.2 0.0 1.1 1 0 0 1 1 1 0 Cytotoxic CS PF04969.11 EGC31744.1 - 1.1e-05 25.8 0.1 2.3e-05 24.8 0.0 1.6 2 0 0 2 2 2 1 CS domain Phosphodiest PF01663.17 EGC31745.1 - 4.3e-66 223.7 1.1 1.3e-65 222.1 0.8 1.8 1 1 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGC31745.1 - 3.9e-10 39.4 0.0 2.1e-08 33.7 0.0 2.3 2 0 0 2 2 2 2 Sulfatase DUF1501 PF07394.7 EGC31745.1 - 0.12 11.1 0.0 0.19 10.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) DUF2562 PF10814.3 EGC31745.1 - 0.2 11.6 0.0 0.32 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2562) Phosphodiest PF01663.17 EGC31746.1 - 4.2e-73 246.7 0.7 6.4e-73 246.1 0.5 1.3 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGC31746.1 - 1.5e-08 34.2 0.1 1.8e-07 30.6 0.0 2.1 1 1 0 2 2 2 1 Sulfatase Pterin_bind PF00809.17 EGC31746.1 - 0.014 14.7 0.0 0.034 13.5 0.0 1.6 1 0 0 1 1 1 0 Pterin binding enzyme DUF1501 PF07394.7 EGC31746.1 - 0.015 14.1 0.0 0.025 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) Vps53_N PF04100.7 EGC31747.1 - 3.9e-112 374.8 19.0 9.5e-112 373.5 13.2 1.7 1 0 0 1 1 1 1 Vps53-like, N-terminal DUF2450 PF10475.4 EGC31747.1 - 9.6e-14 50.9 6.3 3.5e-11 42.5 4.2 2.5 2 0 0 2 2 2 2 Protein of unknown function N-terminal domain (DUF2450) Nop14 PF04147.7 EGC31747.1 - 0.00011 20.3 6.8 0.00011 20.3 4.7 2.2 2 0 0 2 2 2 1 Nop14-like family COG5 PF10392.4 EGC31747.1 - 0.00024 21.0 1.8 0.00098 19.0 1.3 2.1 1 0 0 1 1 1 1 Golgi transport complex subunit 5 COG2 PF06148.6 EGC31747.1 - 0.0032 17.3 3.6 0.0055 16.5 1.3 2.5 2 0 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 TarH PF02203.10 EGC31747.1 - 0.047 13.5 5.6 0.084 12.7 0.3 3.2 4 0 0 4 4 4 0 Tar ligand binding domain homologue Spt5_N PF11942.3 EGC31747.1 - 0.31 11.6 11.9 0.56 10.8 6.7 2.5 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal DUF2201_N PF13203.1 EGC31747.1 - 0.79 8.8 5.2 1.4 8.0 3.6 1.3 1 0 0 1 1 1 0 Putative metallopeptidase domain Pox_A_type_inc PF04508.7 EGC31747.1 - 1.2 9.0 8.7 14 5.8 0.1 4.2 3 0 0 3 3 3 0 Viral A-type inclusion protein repeat HTH_Tnp_4 PF13613.1 EGC31748.1 - 0.016 14.7 0.5 0.12 11.9 0.1 2.4 1 1 1 2 2 2 0 Helix-turn-helix of DDE superfamily endonuclease C2 PF00168.25 EGC31748.1 - 0.018 14.9 0.2 0.049 13.4 0.0 1.8 2 0 0 2 2 2 0 C2 domain gpUL132 PF11359.3 EGC31748.1 - 0.041 13.2 0.1 0.049 12.9 0.1 1.2 1 0 0 1 1 1 0 Glycoprotein UL132 EGF_2 PF07974.8 EGC31749.1 - 0.011 15.9 12.7 0.011 15.9 8.8 2.0 2 0 0 2 2 2 0 EGF-like domain EXS PF03124.9 EGC31750.1 - 3.6e-84 282.7 16.9 4.7e-84 282.3 11.7 1.0 1 0 0 1 1 1 1 EXS family DUF2296 PF10058.4 EGC31751.1 - 1.1e-10 41.1 0.2 1.1e-10 41.1 0.1 1.7 2 0 0 2 2 2 1 Predicted integral membrane metal-binding protein (DUF2296) SdpI PF13630.1 EGC31751.1 - 0.93 9.2 6.7 1.8 8.2 4.7 1.5 1 0 0 1 1 1 0 SdpI/YhfL protein family Aminotran_1_2 PF00155.16 EGC31753.1 - 1.5e-34 119.5 0.0 2e-34 119.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGC31753.1 - 0.0029 16.7 0.0 0.0056 15.8 0.0 1.4 1 0 0 1 1 1 1 Beta-eliminating lyase OTU PF02338.14 EGC31754.1 - 2.6e-21 76.4 3.0 3.3e-21 76.1 0.3 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGC31754.1 - 7.8e-06 25.4 2.4 0.022 14.1 0.0 2.5 1 1 0 2 2 2 2 Peptidase C65 Otubain PP28 PF10252.4 EGC31755.1 - 1.3e-17 63.5 19.9 1.3e-17 63.5 13.8 2.6 2 1 1 3 3 3 1 Casein kinase substrate phosphoprotein PP28 SDA1 PF05285.7 EGC31755.1 - 0.79 8.9 35.4 0.88 8.7 24.5 1.0 1 0 0 1 1 1 0 SDA1 DUF572 PF04502.8 EGC31755.1 - 2.8 7.0 31.8 3.4 6.7 22.0 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF572) tRNA_m1G_MT PF01746.16 EGC31756.1 - 2.8e-30 105.2 0.1 2.8e-30 105.2 0.0 2.0 2 0 0 2 2 2 1 tRNA (Guanine-1)-methyltransferase F5_F8_type_C PF00754.20 EGC31757.1 - 6.8e-25 87.3 3.6 1.1e-24 86.7 2.5 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC31757.1 - 6.5e-20 70.5 0.6 1.8e-19 69.1 0.4 1.8 1 0 0 1 1 1 1 H-type lectin domain Endotoxin_N PF03945.9 EGC31758.1 - 4.6e-24 85.0 7.7 4.6e-24 85.0 5.3 2.0 2 0 0 2 2 2 1 delta endotoxin, N-terminal domain Endotoxin_C PF03944.9 EGC31758.1 - 1.7e-05 24.9 1.4 1.7e-05 24.9 1.0 3.0 3 1 0 3 3 3 1 delta endotoxin HSP70 PF00012.15 EGC31759.1 - 3.9e-94 315.7 16.4 3.9e-94 315.7 11.3 3.0 2 1 0 2 2 2 1 Hsp70 protein MreB_Mbl PF06723.8 EGC31759.1 - 5.1e-05 22.0 0.2 5.1e-05 22.0 0.1 2.6 3 1 0 3 3 3 1 MreB/Mbl protein AAA_33 PF13671.1 EGC31759.1 - 0.032 14.1 0.0 1.5 8.6 0.0 2.8 1 1 0 1 1 1 0 AAA domain Endotoxin_N PF03945.9 EGC31760.1 - 0.013 14.9 0.0 0.16 11.3 0.0 2.2 2 0 0 2 2 2 0 delta endotoxin, N-terminal domain DUF4506 PF14958.1 EGC31760.1 - 0.078 12.5 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4506) OTU PF02338.14 EGC31761.1 - 2.2e-12 47.5 0.0 2.2e-12 47.5 0.0 2.6 3 0 0 3 3 3 1 OTU-like cysteine protease PAT1 PF09770.4 EGC31761.1 - 1.3 7.1 53.4 1.7 6.8 37.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Claudin_2 PF13903.1 EGC31764.1 - 0.0012 18.5 15.1 0.0023 17.6 1.3 3.1 1 1 1 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF4064 PF13273.1 EGC31764.1 - 0.0044 17.1 16.2 0.0067 16.5 1.1 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF4064) DUF1282 PF06930.7 EGC31764.1 - 0.006 16.2 11.1 0.32 10.6 0.3 3.0 2 1 1 3 3 3 2 Protein of unknown function (DUF1282) Amastin PF07344.6 EGC31764.1 - 0.0073 15.9 0.3 0.0073 15.9 0.2 2.8 2 1 1 3 3 3 1 Amastin surface glycoprotein DUF805 PF05656.9 EGC31764.1 - 0.8 9.5 12.1 0.63 9.8 0.5 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF805) DUF3611 PF12263.3 EGC31764.1 - 1 8.7 6.3 0.91 8.8 2.2 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3611) DUF2370 PF10176.4 EGC31764.1 - 1.4 8.2 8.0 6.7 5.9 2.0 3.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2370) 60KD_IMP PF02096.15 EGC31764.1 - 1.6 8.3 6.5 0.11 12.0 0.6 1.8 2 1 0 2 2 2 0 60Kd inner membrane protein PMP22_Claudin PF00822.15 EGC31764.1 - 4.2 6.9 12.8 2.5 7.7 0.3 3.6 3 1 0 4 4 4 0 PMP-22/EMP/MP20/Claudin family Acetyltransf_3 PF13302.1 EGC31765.1 - 5.4e-19 68.7 0.0 6.8e-19 68.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC31765.1 - 0.00024 21.2 0.3 0.0006 19.9 0.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain HATPase_c_5 PF14501.1 EGC31765.1 - 0.0017 18.0 2.4 0.019 14.6 0.2 2.4 1 1 1 2 2 2 1 GHKL domain Acetyltransf_1 PF00583.19 EGC31765.1 - 0.029 14.4 0.1 0.13 12.3 0.1 2.0 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family Ank_2 PF12796.2 EGC31767.1 - 0.022 15.0 0.0 0.022 15.0 0.0 2.3 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) SAP PF02037.22 EGC31768.1 - 0.0032 16.9 0.0 0.0046 16.4 0.0 1.3 1 0 0 1 1 1 1 SAP domain RGS PF00615.14 EGC31769.1 - 1.3e-18 67.1 8.2 1.8e-10 40.9 2.6 2.5 2 0 0 2 2 2 2 Regulator of G protein signaling domain DUF1043 PF06295.7 EGC31770.1 - 0.027 14.1 0.6 0.058 13.0 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF3641 PF12345.3 EGC31770.1 - 0.2 11.5 5.9 2.7 7.8 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3641) DUF2039 PF10217.4 EGC31770.1 - 1.8 8.6 7.3 0.98 9.4 0.4 2.3 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2039) WD40 PF00400.27 EGC31771.1 - 0.00092 19.0 7.3 0.12 12.2 0.0 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat ABC2_membrane_3 PF12698.2 EGC31772.1 - 9.3e-33 113.6 21.7 1.5e-32 113.0 15.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 EGC31772.1 - 1e-28 100.3 0.0 2e-28 99.4 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC2_membrane PF01061.19 EGC31772.1 - 5.7e-23 81.1 14.6 5.7e-23 81.1 10.1 2.8 3 0 0 3 3 3 1 ABC-2 type transporter AAA_21 PF13304.1 EGC31772.1 - 4.5e-15 56.3 8.1 5.9e-11 42.8 0.2 3.5 2 2 0 3 3 3 2 AAA domain AAA_15 PF13175.1 EGC31772.1 - 6.6e-08 32.0 9.4 3.5e-05 23.0 0.5 2.8 2 1 1 3 3 3 2 AAA ATPase domain AAA_10 PF12846.2 EGC31772.1 - 6.6e-05 22.4 0.0 0.00012 21.6 0.0 1.4 1 0 0 1 1 1 1 AAA-like domain AAA_29 PF13555.1 EGC31772.1 - 0.00015 21.1 0.0 0.00045 19.6 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC31772.1 - 0.00046 20.2 0.0 0.0008 19.4 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_23 PF13476.1 EGC31772.1 - 0.00078 19.8 0.5 0.0027 18.0 0.3 2.1 1 1 0 1 1 1 1 AAA domain MobB PF03205.9 EGC31772.1 - 0.0011 18.7 0.0 0.002 17.8 0.0 1.4 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SMC_N PF02463.14 EGC31772.1 - 0.0015 17.8 1.8 0.36 10.0 0.0 2.7 3 0 0 3 3 3 2 RecF/RecN/SMC N terminal domain DUF87 PF01935.12 EGC31772.1 - 0.0019 18.0 0.5 0.0049 16.7 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function DUF87 DUF258 PF03193.11 EGC31772.1 - 0.0023 17.1 0.0 0.004 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC31772.1 - 0.004 16.5 0.0 0.051 12.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC31772.1 - 0.008 15.9 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGC31772.1 - 0.02 15.0 0.4 0.064 13.3 0.1 1.9 2 0 0 2 2 2 0 AAA domain TrwB_AAD_bind PF10412.4 EGC31772.1 - 0.02 13.5 0.0 0.03 12.9 0.0 1.2 1 0 0 1 1 1 0 Type IV secretion-system coupling protein DNA-binding domain PDR_CDR PF06422.7 EGC31772.1 - 0.031 13.9 0.6 0.35 10.5 0.4 2.8 2 0 0 2 2 2 0 CDR ABC transporter MMR_HSR1 PF01926.18 EGC31772.1 - 0.034 14.0 0.1 0.83 9.6 0.0 2.8 3 0 0 3 3 3 0 50S ribosome-binding GTPase AAA_17 PF13207.1 EGC31772.1 - 0.047 14.5 0.0 0.095 13.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGC31772.1 - 0.075 12.9 0.1 0.16 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGC31772.1 - 0.085 12.4 0.0 0.21 11.1 0.0 1.6 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGC31772.1 - 0.085 13.1 0.0 0.28 11.4 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGC31772.1 - 0.18 11.7 0.2 0.3 11.0 0.1 1.3 1 0 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGC31772.1 - 0.2 11.1 0.0 0.32 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family GST_N PF02798.15 EGC31773.1 - 2.6e-10 40.2 0.0 6.2e-10 39.1 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC31773.1 - 6.3e-10 38.9 0.6 5.6e-09 35.8 0.1 2.4 1 1 2 3 3 3 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC31773.1 - 0.00021 21.4 0.0 0.00036 20.6 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC31773.1 - 0.006 16.4 0.0 0.017 14.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Endosulfine PF04667.12 EGC31773.1 - 0.073 13.0 0.8 8 6.5 0.1 2.4 2 0 0 2 2 2 0 cAMP-regulated phosphoprotein/endosulfine conserved region UCR_UQCRX_QCR9 PF05365.7 EGC31773.1 - 0.12 11.9 0.1 1.4 8.5 0.0 2.2 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like Dickkopf_N PF04706.7 EGC31774.1 - 7.6e-07 29.2 5.6 7.6e-07 29.2 3.9 6.7 5 2 3 8 8 8 1 Dickkopf N-terminal cysteine-rich region Act-Frag_cataly PF09192.5 EGC31775.1 - 6.9e-90 300.7 18.0 8.1e-90 300.5 12.4 1.1 1 0 0 1 1 1 1 Actin-fragmin kinase, catalytic AAA_14 PF13173.1 EGC31775.1 - 0.27 11.1 5.2 0.064 13.1 0.4 2.3 2 1 0 2 2 2 0 AAA domain WWbp PF10349.4 EGC31776.1 - 0.22 12.4 7.9 0.52 11.2 5.5 1.6 1 0 0 1 1 1 0 WW-domain ligand protein MMR_HSR1 PF01926.18 EGC31777.1 - 1.9e-06 27.8 2.7 1.3e-05 25.1 0.1 2.9 2 2 0 2 2 2 1 50S ribosome-binding GTPase AIG1 PF04548.11 EGC31777.1 - 0.0037 16.4 1.1 0.38 9.8 0.0 2.9 3 0 0 3 3 3 2 AIG1 family T2SE PF00437.15 EGC31777.1 - 0.0043 15.9 0.0 0.011 14.6 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_29 PF13555.1 EGC31777.1 - 0.0079 15.6 0.0 0.018 14.5 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGC31777.1 - 0.013 16.2 0.0 0.085 13.6 0.0 2.4 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EGC31777.1 - 0.2 11.9 0.0 0.2 11.9 0.0 2.4 2 1 0 2 2 2 0 ABC transporter AAA_18 PF13238.1 EGC31777.1 - 0.58 10.4 0.0 0.58 10.4 0.0 3.2 3 1 0 3 3 3 0 AAA domain Dynamin_N PF00350.18 EGC31777.1 - 7.3 6.3 14.4 0.057 13.2 0.8 3.4 2 2 0 2 2 2 0 Dynamin family Cgr1 PF03879.9 EGC31778.1 - 2e-06 27.9 17.1 2e-06 27.9 11.9 2.3 2 0 0 2 2 2 1 Cgr1 family DUF3332 PF11810.3 EGC31778.1 - 4.4 6.9 20.6 0.38 10.3 5.2 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3332) DUF4407 PF14362.1 EGC31778.1 - 6.9 5.5 18.2 8.4 5.2 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Pro_isomerase PF00160.16 EGC31779.1 - 1.4e-51 174.7 0.1 1.6e-51 174.6 0.1 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD UCH PF00443.24 EGC31780.1 - 8.4e-47 159.5 64.8 8.4e-47 159.5 44.9 4.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGC31780.1 - 2.3e-13 50.0 13.1 2.3e-13 50.0 9.0 2.3 3 0 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein UCH_1 PF13423.1 EGC31780.1 - 1.3e-06 28.1 31.6 1.3e-06 28.1 21.9 7.8 4 2 1 5 5 5 4 Ubiquitin carboxyl-terminal hydrolase Ras PF00071.17 EGC31782.1 - 4.6e-57 191.9 0.1 5.4e-57 191.6 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31782.1 - 2.9e-19 69.7 0.0 8.8e-19 68.1 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC31782.1 - 2.4e-11 43.2 0.0 2.7e-11 42.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC31782.1 - 1.5e-05 24.8 0.0 2.9e-05 23.9 0.0 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC31782.1 - 0.00029 20.3 0.1 0.00042 19.8 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC31782.1 - 0.00054 19.1 0.1 0.00075 18.7 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EGC31782.1 - 0.0021 17.3 0.0 0.043 13.1 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA_14 PF13173.1 EGC31782.1 - 0.0026 17.6 0.0 0.019 14.8 0.0 2.0 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC31782.1 - 0.013 16.3 0.0 0.021 15.6 0.0 1.6 1 1 0 1 1 1 0 AAA domain TK PF00265.13 EGC31782.1 - 0.023 14.2 0.1 3.5 7.1 0.1 2.1 1 1 0 2 2 2 0 Thymidine kinase RasGEF PF00617.14 EGC31783.1 - 3.8e-54 183.2 1.1 3.8e-54 183.2 0.8 2.3 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC31783.1 - 2.1e-22 79.1 4.5 2.1e-22 79.1 3.1 4.6 4 1 0 4 4 4 2 RasGEF N-terminal motif FAT PF02259.18 EGC31783.1 - 0.00062 18.8 2.8 0.0011 18.0 0.1 2.3 2 0 0 2 2 2 1 FAT domain Ribosomal_L19e PF01280.15 EGC31784.1 - 2.4e-12 46.8 0.0 2.9e-12 46.5 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L19e DEAD PF00270.24 EGC31785.1 - 4.4e-42 143.4 5.8 1.7e-41 141.5 1.8 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC31785.1 - 1.1e-28 98.8 0.2 2.3e-28 97.8 0.2 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain AAA_19 PF13245.1 EGC31785.1 - 0.0016 18.1 0.1 0.0056 16.4 0.0 2.0 1 1 0 1 1 1 1 Part of AAA domain tRNA-synt_1b PF00579.20 EGC31785.1 - 0.0032 16.6 0.0 0.0085 15.2 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) CMS1 PF14617.1 EGC31785.1 - 0.0081 15.2 0.5 0.023 13.8 0.0 1.9 3 0 0 3 3 3 1 U3-containing 90S pre-ribosomal complex subunit AAA_30 PF13604.1 EGC31785.1 - 0.013 15.1 0.5 0.14 11.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain Helicase_C_2 PF13307.1 EGC31785.1 - 0.02 14.8 0.0 0.043 13.7 0.0 1.5 1 0 0 1 1 1 0 Helicase C-terminal domain Helicase_RecD PF05127.9 EGC31785.1 - 0.071 12.7 0.5 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Helicase EF1G PF00647.14 EGC31785.1 - 0.11 12.1 0.1 0.22 11.2 0.1 1.4 1 0 0 1 1 1 0 Elongation factor 1 gamma, conserved domain AAA_22 PF13401.1 EGC31785.1 - 0.12 12.5 0.9 0.64 10.1 0.6 2.1 1 1 0 1 1 1 0 AAA domain NYN PF01936.13 EGC31786.1 - 6.2e-22 78.4 0.1 6.2e-22 78.4 0.1 2.9 3 1 0 3 3 3 1 NYN domain OHA PF14418.1 EGC31786.1 - 2.9e-21 74.7 1.9 2.7e-20 71.6 0.0 3.8 3 0 0 3 3 3 1 OST-HTH Associated domain DUF544 PF04424.8 EGC31787.1 - 4.6e-25 87.7 0.3 8.1e-25 86.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DUF423 PF04241.10 EGC31788.1 - 1.3e-24 85.8 0.1 1.8e-24 85.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF423) Ribosomal_S18 PF01084.15 EGC31789.1 - 2.5e-09 36.8 0.0 1.7e-08 34.1 0.0 2.5 2 0 0 2 2 2 1 Ribosomal protein S18 TT_ORF2 PF02957.10 EGC31789.1 - 0.47 11.1 4.3 0.39 11.4 0.4 2.7 2 0 0 2 2 2 0 TT viral ORF2 Wzz PF02706.10 EGC31789.1 - 9.9 5.9 11.4 1 9.1 0.1 3.1 3 0 0 3 3 3 0 Chain length determinant protein UCH PF00443.24 EGC31790.1 - 2.6e-57 193.9 3.4 3.3e-57 193.6 2.3 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC31790.1 - 1.1e-27 97.3 2.1 1.4e-27 96.9 1.4 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Peptidase_C98 PF15499.1 EGC31790.1 - 0.34 10.1 6.9 3.5 6.8 2.4 3.0 2 1 0 2 2 2 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase BRCT PF00533.21 EGC31791.1 - 0.0012 18.9 0.5 0.011 15.8 0.0 3.0 2 1 1 3 3 3 1 BRCA1 C Terminus (BRCT) domain Aha1_N PF09229.6 EGC31792.1 - 8.7e-32 109.8 0.3 1.5e-31 109.0 0.2 1.3 1 0 0 1 1 1 1 Activator of Hsp90 ATPase, N-terminal AHSA1 PF08327.6 EGC31792.1 - 1.1e-13 51.3 0.0 2e-13 50.5 0.0 1.5 1 0 0 1 1 1 1 Activator of Hsp90 ATPase homolog 1-like protein Trp_dioxygenase PF03301.8 EGC31793.1 - 1.7e-119 398.9 3.5 2.1e-119 398.6 2.4 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Rubis-subs-bind PF09273.6 EGC31794.1 - 3.1e-21 75.6 0.1 5.9e-21 74.7 0.1 1.4 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EGC31794.1 - 6.8e-09 36.2 0.0 3.7e-08 33.8 0.0 2.2 1 1 0 1 1 1 1 SET domain Ubiquitin_2 PF14560.1 EGC31794.1 - 0.056 13.7 2.3 0.14 12.4 1.6 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain Sulfotransfer_2 PF03567.9 EGC31795.1 - 5.4e-13 49.2 0.5 5.4e-13 49.2 0.3 2.1 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 EGC31795.1 - 4.1e-06 25.7 0.8 1.6e-05 23.8 0.2 2.3 2 1 0 2 2 2 1 Galactose-3-O-sulfotransferase ODV-E18 PF10717.4 EGC31795.1 - 0.0083 15.5 0.9 0.016 14.6 0.6 1.4 1 0 0 1 1 1 1 Occlusion-derived virus envelope protein ODV-E18 Sulfotransfer_1 PF00685.22 EGC31795.1 - 0.0099 15.1 0.1 0.0099 15.1 0.1 2.2 2 0 0 2 2 2 1 Sulfotransferase domain DUF1980 PF09323.5 EGC31795.1 - 0.011 15.4 7.4 0.023 14.4 5.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Shisa PF13908.1 EGC31795.1 - 0.044 13.9 5.0 0.071 13.2 3.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator YABBY PF04690.8 EGC31795.1 - 0.064 13.4 4.4 0.12 12.6 3.0 1.4 1 0 0 1 1 1 0 YABBY protein DUF106 PF01956.11 EGC31795.1 - 0.07 12.6 5.4 0.12 11.9 3.7 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Peptidase_S49_N PF08496.5 EGC31795.1 - 0.11 12.3 9.7 0.22 11.3 6.7 1.6 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF4199 PF13858.1 EGC31795.1 - 0.11 12.3 1.1 0.27 11.1 0.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) Neur_chan_memb PF02932.11 EGC31795.1 - 0.12 12.2 0.8 0.19 11.6 0.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Mem_trans PF03547.13 EGC31795.1 - 0.13 10.5 0.2 0.13 10.5 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein DUF4179 PF13786.1 EGC31795.1 - 0.18 12.0 7.8 0.041 14.1 2.8 1.9 2 0 0 2 2 1 0 Domain of unknown function (DUF4179) SID-1_RNA_chan PF13965.1 EGC31795.1 - 0.41 8.7 8.0 0.55 8.3 5.6 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Serinc PF03348.10 EGC31795.1 - 0.58 8.8 5.2 0.85 8.2 3.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2570 PF10828.3 EGC31795.1 - 0.6 9.7 15.4 1.8 8.1 10.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DUF4446 PF14584.1 EGC31795.1 - 1 9.1 6.1 2.5 7.8 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4446) ETRAMP PF09716.5 EGC31795.1 - 1.3 9.0 4.7 6 6.8 3.2 2.2 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) GAGA_bind PF06217.7 EGC31795.1 - 1.9 8.3 10.8 3.4 7.5 7.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Herpes_UL25 PF01499.11 EGC31795.1 - 4 5.6 9.1 6 5.0 6.3 1.2 1 0 0 1 1 1 0 Herpesvirus UL25 family DUF4407 PF14362.1 EGC31795.1 - 7 5.5 8.1 11 4.9 5.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) UCH PF00443.24 EGC31796.1 - 1.2e-57 195.0 1.9 1.2e-57 195.0 1.3 2.5 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC31796.1 - 6.2e-26 91.5 0.6 6.2e-26 91.5 0.4 2.8 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase Hira PF07569.6 EGC31796.1 - 0.076 12.2 7.5 1.6 7.9 2.1 2.5 2 0 0 2 2 2 0 TUP1-like enhancer of split zf-H2C2_5 PF13909.1 EGC31796.1 - 6.6 7.1 7.6 1.2 9.5 0.3 2.9 2 0 0 2 2 2 0 C2H2-type zinc-finger domain EGF_2 PF07974.8 EGC31797.1 - 3.1e-56 187.1 326.0 2.8e-05 24.1 9.4 16.1 16 0 0 16 16 16 14 EGF-like domain Laminin_EGF PF00053.19 EGC31797.1 - 0.0051 16.7 276.8 0.47 10.4 6.2 15.6 14 1 1 15 15 15 14 Laminin EGF-like (Domains III and V) ADH_N PF08240.7 EGC31798.1 - 2.7e-26 91.4 4.5 2.7e-26 91.4 3.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC31798.1 - 7e-17 61.1 0.1 1.2e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC31798.1 - 0.0018 19.1 0.0 0.0032 18.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EGC31798.1 - 0.058 12.9 0.2 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase DUF2284 PF10050.4 EGC31798.1 - 0.063 12.8 0.0 0.13 11.8 0.0 1.5 1 0 0 1 1 1 0 Predicted metal-binding protein (DUF2284) 2-Hacid_dh_C PF02826.14 EGC31798.1 - 0.087 11.9 0.1 0.13 11.4 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N PF00107.21 EGC31799.1 - 3.5e-18 65.3 0.0 6.2e-18 64.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC31799.1 - 4.9e-18 64.8 2.4 4.9e-18 64.8 1.7 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ELFV_dehydrog PF00208.16 EGC31799.1 - 0.0073 15.9 0.1 0.011 15.2 0.1 1.2 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EGC31799.1 - 0.02 14.0 0.1 0.031 13.4 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF3430 PF11912.3 EGC31800.1 - 2.5e-24 86.2 45.6 4.8e-24 85.3 31.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) PAF-AH_p_II PF03403.8 EGC31802.1 - 0.0085 14.4 0.4 0.015 13.6 0.3 1.3 1 0 0 1 1 1 1 Platelet-activating factor acetylhydrolase, isoform II YcgR PF07317.7 EGC31802.1 - 0.039 13.6 0.3 0.35 10.6 0.1 2.3 1 1 1 2 2 2 0 Flagellar regulator YcgR GDPD PF03009.12 EGC31803.1 - 1.3e-48 165.7 0.1 2.8e-47 161.4 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family CBM_20 PF00686.14 EGC31803.1 - 8.3e-15 54.1 0.7 8.3e-15 54.1 0.5 2.6 3 0 0 3 3 3 1 Starch binding domain Methyltransf_7 PF03492.10 EGC31804.1 - 3e-16 59.1 11.7 5.8e-16 58.1 8.1 1.4 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_23 PF13489.1 EGC31804.1 - 0.0091 15.7 0.1 0.018 14.7 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Sigma70_r1_1 PF03979.9 EGC31804.1 - 0.015 15.2 4.4 0.029 14.2 0.7 2.7 3 0 0 3 3 3 0 Sigma-70 factor, region 1.1 Methyltransf_31 PF13847.1 EGC31804.1 - 0.032 13.8 0.2 0.32 10.5 0.1 2.4 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC31804.1 - 0.068 13.6 0.1 0.21 12.1 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain OPT PF03169.10 EGC31804.1 - 0.3 9.4 0.6 1.9 6.8 0.0 1.9 2 0 0 2 2 2 0 OPT oligopeptide transporter protein TIG PF01833.19 EGC31805.1 - 9.1e-09 35.2 15.8 0.00034 20.5 3.8 3.6 3 0 0 3 3 3 2 IPT/TIG domain LRR_8 PF13855.1 EGC31805.1 - 2.2e-05 24.1 12.7 9.2e-05 22.1 2.7 3.4 2 1 1 3 3 3 2 Leucine rich repeat EGF_2 PF07974.8 EGC31805.1 - 0.00018 21.6 61.0 0.0052 16.9 3.4 4.8 4 0 0 4 4 4 3 EGF-like domain LRR_6 PF13516.1 EGC31805.1 - 0.0016 18.2 8.2 0.81 9.9 0.2 6.0 5 0 0 5 5 4 1 Leucine Rich repeat LRR_4 PF12799.2 EGC31805.1 - 0.0024 17.4 20.7 0.0032 17.0 3.5 6.0 4 2 1 5 5 5 1 Leucine Rich repeats (2 copies) EB PF01683.13 EGC31805.1 - 0.0076 16.3 4.2 0.0076 16.3 2.9 5.0 3 2 1 4 4 3 1 EB module SKG6 PF08693.5 EGC31805.1 - 0.062 12.6 1.4 0.12 11.7 1.0 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Rabaptin PF03528.10 EGC31805.1 - 0.092 12.6 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 Rabaptin LRR_1 PF00560.28 EGC31805.1 - 0.095 12.7 0.2 0.095 12.7 0.2 7.5 6 1 1 7 7 7 0 Leucine Rich Repeat LRR_7 PF13504.1 EGC31805.1 - 2.9 8.4 10.2 4.8 7.8 0.2 5.6 5 1 0 5 5 4 0 Leucine rich repeat hEGF PF12661.2 EGC31805.1 - 5 7.4 22.0 0.035 14.1 1.0 4.6 4 0 0 4 4 4 0 Human growth factor-like EGF Acetyltransf_5 PF13444.1 EGC31806.1 - 3.9e-07 30.5 0.3 0.00011 22.7 0.1 3.2 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC31806.1 - 0.00096 19.1 0.0 0.0016 18.4 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family ADH_N PF08240.7 EGC31808.1 - 2e-26 91.8 3.9 2e-26 91.8 2.7 1.6 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC31808.1 - 1.8e-16 59.8 0.1 2.7e-16 59.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC31808.1 - 0.001 19.9 0.0 0.0017 19.2 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase CoA_binding PF02629.14 EGC31808.1 - 0.034 14.6 0.2 0.14 12.6 0.1 2.0 2 0 0 2 2 2 0 CoA binding domain ELFV_dehydrog PF00208.16 EGC31808.1 - 0.039 13.5 0.5 0.057 12.9 0.4 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 2-Hacid_dh_C PF02826.14 EGC31808.1 - 0.13 11.4 0.2 0.18 10.9 0.1 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain XPA_N PF01286.13 EGC31808.1 - 2.4 7.8 5.8 2 8.1 1.3 2.2 2 0 0 2 2 2 0 XPA protein N-terminal ADH_N PF08240.7 EGC31809.1 - 8e-22 77.0 7.9 8e-22 77.0 5.5 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC31809.1 - 6.3e-16 58.1 0.1 9.9e-16 57.4 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC31809.1 - 0.00017 22.4 0.0 0.00027 21.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PEARLI-4 PF05278.7 EGC31810.1 - 0.0066 15.8 2.9 0.0066 15.8 2.0 1.7 2 0 0 2 2 2 1 Arabidopsis phospholipase-like protein (PEARLI 4) AAA_13 PF13166.1 EGC31810.1 - 0.049 12.1 11.6 0.063 11.7 8.0 1.1 1 0 0 1 1 1 0 AAA domain CCDC-167 PF15188.1 EGC31810.1 - 0.25 11.2 10.4 0.045 13.6 3.6 2.3 1 1 1 2 2 2 0 Coiled-coil domain-containing protein 167 Nup54 PF13874.1 EGC31810.1 - 0.82 9.3 10.0 0.3 10.7 3.7 2.0 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF45 PF01863.12 EGC31810.1 - 0.96 9.1 4.2 1 9.0 2.5 1.3 1 1 0 1 1 1 0 Protein of unknown function DUF45 Laminin_II PF06009.7 EGC31810.1 - 6.7 6.4 13.3 1.2 8.8 4.0 2.4 1 1 2 3 3 3 0 Laminin Domain II CENP-F_leu_zip PF10473.4 EGC31810.1 - 7.9 6.3 19.4 3 7.6 9.4 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 HSP90 PF00183.13 EGC31811.1 - 3.9e-243 807.6 40.4 5.2e-243 807.2 28.0 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EGC31811.1 - 7.4e-11 41.8 0.5 7.4e-11 41.8 0.3 3.0 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC31811.1 - 1.3e-10 40.9 0.1 2.8e-10 39.8 0.1 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase GRAM PF02893.15 EGC31812.1 - 1.2e-11 43.9 0.6 2.6e-11 42.8 0.1 1.9 2 0 0 2 2 2 1 GRAM domain His_Phos_1 PF00300.17 EGC31813.1 - 5.1e-22 78.6 0.0 8e-22 78.0 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) Prefoldin_2 PF01920.15 EGC31814.1 - 0.0036 17.0 1.7 0.0036 17.0 1.2 2.2 2 0 0 2 2 2 1 Prefoldin subunit DUF3121 PF11319.3 EGC31814.1 - 0.2 11.1 4.0 0.044 13.2 0.7 1.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3121) Tom22 PF04281.8 EGC31814.1 - 0.41 10.1 4.8 0.13 11.7 0.4 2.0 2 0 0 2 2 2 0 Mitochondrial import receptor subunit Tom22 Vip3A_N PF12495.3 EGC31815.1 - 0.012 15.2 0.0 0.016 14.9 0.0 1.2 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal Thioredoxin_6 PF13848.1 EGC31815.1 - 0.061 13.1 0.1 0.51 10.1 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin-like domain EF-hand_7 PF13499.1 EGC31815.1 - 0.071 13.2 2.0 2.8 8.1 0.4 2.8 2 2 0 2 2 2 0 EF-hand domain pair DUF4030 PF13222.1 EGC31815.1 - 0.15 11.7 0.5 2.4 7.8 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF4030) MFS_1 PF07690.11 EGC31816.1 - 1.1e-20 73.6 33.2 5e-11 41.9 7.3 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGC31816.1 - 8e-20 70.6 25.9 3.1e-19 68.6 18.4 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein RCC1 PF00415.13 EGC31817.1 - 6e-70 231.2 6.9 1.1e-11 44.7 0.2 7.3 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC31817.1 - 2.5e-39 132.0 14.8 7.1e-07 28.6 0.2 7.4 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Nop14 PF04147.7 EGC31818.1 - 0.018 12.9 33.7 0.024 12.5 23.3 1.2 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGC31818.1 - 0.038 13.0 29.7 0.05 12.6 20.6 1.1 1 0 0 1 1 1 0 BUD22 SprA-related PF12118.3 EGC31818.1 - 0.22 10.8 16.1 0.28 10.4 11.2 1.2 1 0 0 1 1 1 0 SprA-related family Herpes_DNAp_acc PF04929.7 EGC31818.1 - 0.35 9.7 16.5 0.49 9.2 11.4 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mem_trans PF03547.13 EGC31818.1 - 1.9 6.6 4.4 2.2 6.4 3.0 1.2 1 0 0 1 1 1 0 Membrane transport protein Hid1 PF12722.2 EGC31818.1 - 4.1 4.9 21.9 4.9 4.6 15.2 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Macoilin PF09726.4 EGC31818.1 - 6.5 4.8 16.3 7.5 4.6 11.3 1.1 1 0 0 1 1 1 0 Transmembrane protein Daxx PF03344.10 EGC31818.1 - 7 5.0 30.6 10 4.4 21.2 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGC31818.1 - 7.9 5.6 38.3 0.35 10.1 22.7 1.4 2 0 0 2 2 2 0 SDA1 Pet191_N PF10203.4 EGC31819.1 - 0.08 12.9 2.0 0.13 12.3 1.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 Uds1 PF15456.1 EGC31819.1 - 0.12 12.3 0.2 0.19 11.6 0.1 1.3 1 0 0 1 1 1 0 Up-regulated During Septation Amnionless PF14828.1 EGC31820.1 - 0.0054 15.2 0.1 0.0081 14.6 0.0 1.2 1 0 0 1 1 1 1 Amnionless Aminotran_1_2 PF00155.16 EGC31821.1 - 2.6e-49 168.1 0.0 3e-49 167.9 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II FYVE PF01363.16 EGC31822.1 - 2.4e-18 65.7 12.0 5.6e-18 64.5 8.3 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arm PF00514.18 EGC31822.1 - 1.3e-12 46.9 3.5 0.00012 21.8 0.0 6.3 7 0 0 7 7 7 3 Armadillo/beta-catenin-like repeat V-ATPase_H_N PF03224.9 EGC31822.1 - 3.5e-08 32.9 4.2 3.5e-08 32.9 2.9 2.9 1 1 2 3 3 3 1 V-ATPase subunit H Apc15p PF05841.6 EGC31822.1 - 5.8 7.6 12.6 15 6.3 8.7 1.6 1 0 0 1 1 1 0 Apc15p protein Aldo_ket_red PF00248.16 EGC31823.1 - 3.4e-59 199.9 0.0 4e-59 199.7 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family Glyco_hydro_12 PF01670.11 EGC31823.1 - 0.11 12.3 0.0 0.26 11.0 0.0 1.7 2 0 0 2 2 2 0 Glycosyl hydrolase family 12 CH PF00307.26 EGC31824.1 - 1.3e-10 41.2 0.0 1.3e-10 41.2 0.0 3.1 3 1 1 4 4 4 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC31824.1 - 0.0048 16.5 1.6 0.017 14.7 0.0 2.6 2 0 0 2 2 2 1 CAMSAP CH domain CDC24 PF06395.6 EGC31824.1 - 0.0048 16.9 1.3 0.043 13.8 0.0 3.3 3 0 0 3 3 3 1 CDC24 Calponin Aph-1 PF06105.7 EGC31825.1 - 2.5e-84 282.2 2.6 3.1e-84 281.9 1.8 1.0 1 0 0 1 1 1 1 Aph-1 protein DUF1510 PF07423.6 EGC31825.1 - 0.001 18.4 5.2 0.0021 17.5 3.6 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) PsaL PF02605.10 EGC31825.1 - 0.12 11.9 2.7 2.4 7.6 0.5 2.3 1 1 1 2 2 2 0 Photosystem I reaction centre subunit XI DUF2324 PF10086.4 EGC31825.1 - 0.24 10.5 11.1 0.24 10.5 0.3 2.4 2 0 0 2 2 2 0 Putative membrane peptidase family (DUF2324) DUF106 PF01956.11 EGC31825.1 - 0.68 9.4 6.2 0.094 12.2 0.6 2.4 1 1 1 2 2 2 0 Integral membrane protein DUF106 G-7-MTase PF12803.2 EGC31825.1 - 1.2 8.1 4.8 1.8 7.6 3.3 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Nop25 PF09805.4 EGC31825.1 - 1.8 8.6 13.2 2.5 8.1 9.1 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2457 PF10446.4 EGC31825.1 - 3.6 6.1 16.4 4.9 5.7 11.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) P5-ATPase PF12409.3 EGC31825.1 - 5.6 6.8 7.6 4.1 7.2 0.1 2.6 2 0 0 2 2 2 0 P5-type ATPase cation transporter RasGEF PF00617.14 EGC31826.1 - 2.4e-61 206.7 2.2 7e-61 205.2 1.5 1.9 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC31826.1 - 2.3e-20 72.6 0.9 2.3e-20 72.6 0.7 4.1 5 0 0 5 5 5 1 RasGEF N-terminal motif DUF885 PF05960.6 EGC31826.1 - 0.2 10.7 0.3 0.33 10.0 0.2 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) NCA2 PF08637.5 EGC31827.1 - 1.5e-52 178.2 11.0 1.5e-52 178.2 7.6 2.7 2 1 0 2 2 2 1 ATP synthase regulation protein NCA2 MIT PF04212.13 EGC31828.1 - 1.7e-27 95.0 5.0 7.8e-15 54.5 0.5 2.4 2 0 0 2 2 2 2 MIT (microtubule interacting and transport) domain LIM PF00412.17 EGC31828.1 - 6.5e-08 32.5 0.3 2.7e-05 24.1 0.2 2.4 1 1 1 2 2 2 2 LIM domain Arrestin_C PF02752.17 EGC31828.1 - 1e-05 25.6 0.1 1e-05 25.6 0.0 2.6 3 0 0 3 3 3 1 Arrestin (or S-antigen), C-terminal domain A2M_N PF01835.14 EGC31828.1 - 0.074 13.3 1.4 0.22 11.7 0.0 2.3 2 0 0 2 2 2 0 MG2 domain Calpain_inhib PF00748.14 EGC31828.1 - 0.65 10.3 4.0 42 4.4 0.0 2.8 3 0 0 3 3 3 0 Calpain inhibitor Nop53 PF07767.6 EGC31829.1 - 3.8e-25 88.6 46.2 5.2e-18 65.2 12.1 2.2 1 1 1 2 2 2 2 Nop53 (60S ribosomal biogenesis) ScpA_ScpB PF02616.9 EGC31829.1 - 0.64 9.5 24.1 0.52 9.8 3.2 2.3 2 0 0 2 2 2 0 ScpA/B protein zf-CCHC PF00098.18 EGC31831.1 - 3.5e-06 26.6 1.4 7.1e-06 25.6 0.9 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC31831.1 - 0.06 13.0 1.3 0.21 11.2 0.1 2.3 2 0 0 2 2 2 0 Zinc knuckle PAH PF02671.16 EGC31832.1 - 0.099 12.2 0.1 0.27 10.8 0.1 1.7 1 0 0 1 1 1 0 Paired amphipathic helix repeat VPR PF00522.13 EGC31832.1 - 0.12 12.2 1.1 0.16 11.7 0.7 1.4 1 1 0 1 1 1 0 VPR/VPX protein UBA_3 PF09288.5 EGC31832.1 - 0.17 11.5 2.1 1.8 8.1 0.0 2.4 2 0 0 2 2 2 0 Fungal ubiquitin-associated domain SAP30_Sin3_bdg PF13867.1 EGC31832.1 - 0.23 11.3 3.4 1.3 8.9 0.7 2.3 2 0 0 2 2 2 0 Sin3 binding region of histone deacetylase complex subunit SAP30 IncA PF04156.9 EGC31833.1 - 0.08 12.5 0.3 9.9 5.7 0.0 2.4 2 0 0 2 2 2 0 IncA protein DUF4131 PF13567.1 EGC31833.1 - 0.2 11.0 15.9 0.8 9.0 0.0 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) DUF3430 PF11912.3 EGC31834.1 - 1.1e-06 28.6 28.3 1.3e-06 28.3 19.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC31834.1 - 0.6 10.1 10.7 0.71 9.9 0.2 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) Plasmodium_Vir PF05795.6 EGC31835.1 - 0.066 12.3 3.5 0.092 11.9 2.4 1.3 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF2569 PF10754.4 EGC31835.1 - 1.5 9.0 11.9 2.6 8.2 0.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2569) PMP22_Claudin PF00822.15 EGC31835.1 - 6.3 6.4 10.2 0.95 9.1 3.0 2.3 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin family MFS_1 PF07690.11 EGC31836.1 - 5.3e-22 78.0 31.6 5.3e-22 78.0 21.9 1.6 2 0 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGC31836.1 - 4e-08 32.0 29.8 7.7e-05 21.2 11.9 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein Bac_export_2 PF01312.14 EGC31836.1 - 0.004 16.1 1.6 0.004 16.1 1.1 1.8 3 0 0 3 3 3 1 FlhB HrpN YscU SpaS Family HATPase_c_3 PF13589.1 EGC31837.1 - 5.8e-20 71.3 1.0 5.8e-20 71.3 0.7 2.4 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC31837.1 - 0.0037 16.9 1.6 0.0055 16.4 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CAP PF00188.21 EGC31838.1 - 0.00021 21.7 1.6 0.00021 21.7 1.1 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family IPT PF01745.11 EGC31839.1 - 7.8e-33 113.5 0.1 2.1e-31 108.9 0.1 2.1 1 1 0 1 1 1 1 Isopentenyl transferase AAA_17 PF13207.1 EGC31839.1 - 0.00027 21.7 0.5 0.00055 20.7 0.4 1.8 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC31839.1 - 0.00043 20.4 0.0 0.02 15.0 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGC31839.1 - 0.017 15.0 3.3 0.87 9.4 0.0 2.6 2 1 0 2 2 2 0 AAA domain EndoU_bacteria PF14436.1 EGC31839.1 - 0.045 13.5 2.1 0.052 13.3 0.3 2.0 2 1 0 2 2 2 0 Bacterial EndoU nuclease AAA_18 PF13238.1 EGC31839.1 - 0.045 14.0 2.3 0.067 13.4 0.3 2.2 2 1 0 2 2 2 0 AAA domain RRM_5 PF13893.1 EGC31840.1 - 7.1e-06 25.7 0.0 2e-05 24.3 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC31840.1 - 0.00018 21.0 0.4 0.00069 19.2 0.1 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EGC31840.1 - 0.00027 20.5 1.0 0.00062 19.3 0.7 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF747 PF05346.6 EGC31841.1 - 1.6e-102 342.9 20.9 1.6e-102 342.9 14.5 1.7 2 0 0 2 2 2 1 Eukaryotic membrane protein family YopH_N PF09013.5 EGC31841.1 - 0.078 12.6 0.1 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 YopH, N-terminal Orai-1 PF07856.7 EGC31841.1 - 1.8 8.0 8.5 13 5.2 5.9 2.3 1 1 0 1 1 1 0 Mediator of CRAC channel activity ATG_C PF09333.6 EGC31842.1 - 1.8e-13 50.4 0.1 3e-06 27.3 0.0 2.5 2 0 0 2 2 2 2 ATG C terminal domain zf-B_box PF00643.19 EGC31842.1 - 0.0002 21.1 9.5 0.00034 20.4 6.6 1.3 1 0 0 1 1 1 1 B-box zinc finger Mito_carr PF00153.22 EGC31842.1 - 0.11 12.1 2.0 2.5 7.8 0.0 2.7 2 1 0 2 2 2 0 Mitochondrial carrier protein UPF0014 PF03649.8 EGC31843.1 - 0.085 11.9 0.0 0.11 11.5 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) Tox-MPTase5 PF15641.1 EGC31843.1 - 0.099 12.6 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 MOR2-PAG1_N PF14222.1 EGC31843.1 - 0.53 8.8 3.2 0.63 8.6 2.2 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal AAA_23 PF13476.1 EGC31844.1 - 4.5e-18 66.3 4.2 4.5e-18 66.3 2.9 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGC31844.1 - 8.1e-16 57.9 1.0 1.4e-15 57.0 0.7 1.4 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_15 PF13175.1 EGC31844.1 - 9.3e-06 24.9 7.5 9.3e-06 24.9 5.2 1.6 2 0 0 2 2 2 1 AAA ATPase domain AAA_29 PF13555.1 EGC31844.1 - 7.5e-05 22.1 0.2 0.00021 20.7 0.0 1.8 2 0 0 2 2 2 1 P-loop containing region of AAA domain CDC45 PF02724.9 EGC31844.1 - 0.0064 14.5 5.9 0.0081 14.2 4.1 1.1 1 0 0 1 1 1 1 CDC45-like protein Serglycin PF04360.7 EGC31844.1 - 0.0077 15.9 5.3 0.0096 15.6 1.9 2.2 2 1 0 2 2 2 1 Serglycin MukB PF04310.7 EGC31844.1 - 0.015 14.6 0.0 0.024 13.9 0.0 1.3 1 0 0 1 1 1 0 MukB N-terminal AF-4 PF05110.8 EGC31844.1 - 0.061 11.1 24.5 0.083 10.7 17.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein XRCC4 PF06632.7 EGC31844.1 - 0.54 9.0 9.2 0.14 10.9 4.4 1.4 2 0 0 2 2 2 0 DNA double-strand break repair and V(D)J recombination protein XRCC4 AAA_11 PF13086.1 EGC31844.1 - 0.8 9.2 5.4 0.11 12.1 0.2 1.8 1 1 1 2 2 2 0 AAA domain AAA_21 PF13304.1 EGC31844.1 - 1.4 8.8 10.8 0.1 12.5 2.6 2.3 2 1 0 2 2 2 0 AAA domain Herpes_capsid PF06112.6 EGC31844.1 - 7.6 6.5 11.0 9.4 6.2 6.6 1.8 2 0 0 2 2 2 0 Gammaherpesvirus capsid protein SMC_N PF02463.14 EGC31845.1 - 2.8e-11 43.0 1.4 4.1e-11 42.5 1.0 1.2 1 0 0 1 1 1 1 RecF/RecN/SMC N terminal domain COG5 PF10392.4 EGC31845.1 - 0.49 10.3 12.1 0.13 12.2 5.1 2.3 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF3023 PF11224.3 EGC31845.1 - 0.79 9.3 6.8 0.25 11.0 0.6 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3023) HALZ PF02183.13 EGC31846.1 - 0.00023 20.7 0.6 0.00023 20.7 0.4 1.7 2 0 0 2 2 2 1 Homeobox associated leucine zipper Microtub_assoc PF07989.6 EGC31846.1 - 0.0016 18.2 0.5 0.0026 17.5 0.4 1.4 1 0 0 1 1 1 1 Microtubule associated bZIP_1 PF00170.16 EGC31846.1 - 0.0029 17.5 0.5 0.0052 16.7 0.4 1.5 1 0 0 1 1 1 1 bZIP transcription factor MbeD_MobD PF04899.7 EGC31846.1 - 0.0029 17.4 0.1 0.0046 16.8 0.1 1.3 1 0 0 1 1 1 1 MbeD/MobD like TMF_DNA_bd PF12329.3 EGC31846.1 - 0.0041 16.8 1.4 0.0078 16.0 0.9 1.5 1 0 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DivIC PF04977.10 EGC31846.1 - 0.0055 16.1 1.6 0.0091 15.4 1.1 1.4 1 0 0 1 1 1 1 Septum formation initiator Matrilin_ccoil PF10393.4 EGC31846.1 - 0.027 13.8 0.5 0.047 13.0 0.4 1.4 1 0 0 1 1 1 0 Trimeric coiled-coil oligomerisation domain of matrilin BLOC1_2 PF10046.4 EGC31846.1 - 0.046 13.8 0.7 0.76 9.9 0.4 2.0 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 FlaC_arch PF05377.6 EGC31846.1 - 0.062 13.2 0.4 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Seryl_tRNA_N PF02403.17 EGC31846.1 - 0.062 13.3 1.2 0.078 13.0 0.9 1.2 1 0 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain bZIP_2 PF07716.10 EGC31846.1 - 0.15 11.9 0.7 0.48 10.2 0.6 1.6 1 1 1 2 2 2 0 Basic region leucine zipper RIC3 PF15361.1 EGC31847.1 - 0.0056 16.9 0.2 0.0087 16.3 0.1 1.2 1 0 0 1 1 1 1 Resistance to inhibitors of cholinesterase homologue 3 TRP PF06011.7 EGC31847.1 - 0.011 14.3 0.1 0.011 14.3 0.1 1.1 1 0 0 1 1 1 0 Transient receptor potential (TRP) ion channel DUF3290 PF11694.3 EGC31847.1 - 0.053 13.2 0.1 0.11 12.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Claudin_2 PF13903.1 EGC31847.1 - 0.08 12.6 0.2 0.18 11.5 0.0 1.6 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Ribosomal_L3 PF00297.17 EGC31848.1 - 1.2e-36 126.5 6.2 3.7e-35 121.6 4.3 2.1 1 1 0 1 1 1 1 Ribosomal protein L3 RRM_1 PF00076.17 EGC31849.1 - 6.9e-46 153.7 1.8 2.4e-16 59.0 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC31849.1 - 2.5e-26 91.4 0.0 1.5e-07 31.2 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31849.1 - 2e-20 72.3 3.6 2.5e-07 30.4 0.0 3.9 4 1 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC31849.1 - 0.00052 19.8 2.5 2 8.2 0.0 3.4 3 0 0 3 3 3 2 RNA binding motif Nup35_RRM_2 PF14605.1 EGC31849.1 - 0.00072 19.2 1.0 0.77 9.5 0.0 3.4 3 0 0 3 3 3 1 Nup53/35/40-type RNA recognition motif RNA_bind PF08675.6 EGC31849.1 - 0.0027 17.6 0.0 0.25 11.3 0.0 2.8 2 0 0 2 2 2 1 RNA binding domain Nup35_RRM PF05172.8 EGC31849.1 - 0.041 13.6 0.1 0.041 13.6 0.0 2.8 2 1 0 2 2 2 0 Nup53/35/40-type RNA recognition motif MMR_HSR1 PF01926.18 EGC31850.1 - 2.6e-23 82.1 1.3 6.3e-23 80.9 0.9 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC31850.1 - 9.5e-11 41.7 3.2 2.7e-06 27.3 0.0 3.0 2 1 1 3 3 3 2 Dynamin family GTP_EFTU PF00009.22 EGC31850.1 - 2.3e-09 36.9 4.1 0.00039 19.8 1.3 3.4 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGC31850.1 - 3.5e-09 36.1 0.8 3.5e-09 36.1 0.5 2.3 1 1 1 2 2 2 1 Ferrous iron transport protein B KH_2 PF07650.12 EGC31850.1 - 1.4e-08 34.2 1.3 2.5e-08 33.3 0.1 2.1 2 0 0 2 2 2 1 KH domain PduV-EutP PF10662.4 EGC31850.1 - 5.9e-07 29.0 1.1 0.049 13.1 0.0 3.5 1 1 2 3 3 3 2 Ethanolamine utilisation - propanediol utilisation AIG1 PF04548.11 EGC31850.1 - 8.1e-07 28.3 0.2 8.1e-07 28.3 0.1 2.3 3 0 0 3 3 3 1 AIG1 family Miro PF08477.8 EGC31850.1 - 1e-06 29.2 0.0 3.7e-06 27.4 0.0 2.1 1 1 0 1 1 1 1 Miro-like protein DUF258 PF03193.11 EGC31850.1 - 0.00026 20.2 0.1 0.00062 18.9 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function, DUF258 YgbB PF02542.11 EGC31850.1 - 0.0018 18.1 0.1 0.0037 17.0 0.0 1.5 1 0 0 1 1 1 1 YgbB family ABC_tran PF00005.22 EGC31850.1 - 0.0056 16.9 2.8 0.017 15.3 1.9 1.9 1 1 0 1 1 1 1 ABC transporter AAA_29 PF13555.1 EGC31850.1 - 0.0063 16.0 0.0 0.028 13.9 0.0 2.1 2 0 0 2 2 2 1 P-loop containing region of AAA domain Arf PF00025.16 EGC31850.1 - 0.0097 15.1 2.9 1.1 8.4 0.0 2.7 2 1 0 2 2 2 1 ADP-ribosylation factor family FtsK_SpoIIIE PF01580.13 EGC31850.1 - 0.018 14.5 0.0 0.058 12.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EGC31850.1 - 0.025 14.0 2.9 1.4 8.3 0.6 2.5 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain GSH_synthase PF03199.10 EGC31850.1 - 0.026 14.6 0.7 0.068 13.2 0.5 1.7 1 0 0 1 1 1 0 Eukaryotic glutathione synthase AAA_28 PF13521.1 EGC31850.1 - 0.04 13.8 0.0 0.099 12.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain ATP_bind_1 PF03029.12 EGC31850.1 - 0.041 13.4 1.2 6 6.3 0.4 3.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein AAA_10 PF12846.2 EGC31850.1 - 0.051 13.0 0.2 0.12 11.7 0.0 1.6 1 1 0 2 2 2 0 AAA-like domain AAA PF00004.24 EGC31850.1 - 0.072 13.2 1.9 0.43 10.7 1.3 2.2 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC31850.1 - 0.088 13.6 5.5 0.51 11.1 2.1 3.1 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGC31850.1 - 0.4 11.0 3.7 1.4 9.2 0.7 2.8 1 1 0 2 2 2 0 AAA domain Sugar_tr PF00083.19 EGC31851.1 - 3.1 6.2 2.5 11 4.4 1.8 1.9 1 0 0 1 1 1 0 Sugar (and other) transporter AAA_2 PF07724.9 EGC31852.1 - 2.7e-41 141.3 0.0 1.4e-32 112.9 0.0 2.7 2 1 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGC31852.1 - 2.8e-14 53.4 0.1 4.8e-06 26.7 0.0 3.1 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGC31852.1 - 1.9e-07 30.8 1.9 1.9e-07 30.8 1.3 2.7 2 1 0 2 2 2 1 C-terminal, D2-small domain, of ClpB protein AAA_5 PF07728.9 EGC31852.1 - 6.8e-07 29.0 0.1 2.6e-05 23.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGC31852.1 - 5.6e-05 23.9 0.0 0.00019 22.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGC31852.1 - 0.00012 21.3 0.0 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGC31852.1 - 0.00025 20.9 0.1 0.25 11.2 0.0 3.0 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC31852.1 - 0.00048 20.1 0.0 0.0012 18.8 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain Sigma54_activat PF00158.21 EGC31852.1 - 0.0012 18.3 0.0 0.061 12.7 0.0 2.5 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_18 PF13238.1 EGC31852.1 - 0.0014 18.9 0.1 0.005 17.1 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC31852.1 - 0.0016 18.6 0.1 0.02 15.0 0.0 2.4 1 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGC31852.1 - 0.0035 16.4 0.0 0.1 11.6 0.0 2.3 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EGC31852.1 - 0.014 14.5 0.0 0.03 13.4 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin IstB_IS21 PF01695.12 EGC31852.1 - 0.016 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein T2SE PF00437.15 EGC31852.1 - 0.025 13.4 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein SRP54 PF00448.17 EGC31852.1 - 0.047 13.1 0.0 0.11 11.9 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EGC31852.1 - 0.048 13.5 0.0 0.17 11.7 0.0 2.0 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGC31852.1 - 0.054 12.9 0.2 0.22 11.0 0.2 2.1 1 1 0 1 1 1 0 DEAD/DEAH box helicase MobB PF03205.9 EGC31852.1 - 0.057 13.1 0.1 0.14 11.8 0.1 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B Dev_Cell_Death PF10539.4 EGC31852.1 - 0.069 12.6 0.0 0.31 10.5 0.0 2.0 1 1 1 2 2 2 0 Development and cell death domain AAA_28 PF13521.1 EGC31852.1 - 0.074 13.0 0.0 0.22 11.4 0.0 1.8 1 0 0 1 1 1 0 AAA domain DUF536 PF04394.9 EGC31852.1 - 0.12 12.1 3.5 0.24 11.1 1.4 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF536 ABC_tran PF00005.22 EGC31852.1 - 2 8.6 4.9 8.7 6.6 0.0 3.3 4 1 0 4 4 3 0 ABC transporter Membrane_bind PF14564.1 EGC31853.1 - 1e-34 118.9 0.0 1.6e-34 118.3 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 EGC31853.1 - 2.9e-30 103.8 0.3 4.4e-30 103.2 0.2 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin zf-RING_2 PF13639.1 EGC31854.1 - 6.9e-08 32.1 12.0 1.6e-07 31.0 8.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31854.1 - 2.7e-06 26.9 10.1 5.4e-06 25.9 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC31854.1 - 3.1e-06 27.1 14.6 7e-06 25.9 10.1 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31854.1 - 1.9e-05 24.2 14.2 5e-05 22.8 9.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31854.1 - 9.9e-05 22.3 8.2 0.00043 20.3 5.7 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC31854.1 - 0.00037 20.1 13.3 0.00076 19.1 9.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC31854.1 - 0.012 15.2 4.9 0.012 15.2 3.4 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGC31854.1 - 0.015 14.8 11.6 0.036 13.6 8.0 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF721 PF05258.7 EGC31854.1 - 0.075 13.2 0.1 0.16 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF721) zf-C3HC4_4 PF15227.1 EGC31854.1 - 0.71 9.7 15.7 0.53 10.1 9.0 2.3 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING Cript PF10235.4 EGC31854.1 - 5 7.5 9.1 0.71 10.2 2.9 2.1 2 0 0 2 2 2 0 Microtubule-associated protein CRIPT ATG16 PF08614.6 EGC31854.1 - 7.3 6.3 29.1 6.9 6.4 18.8 1.9 1 1 0 1 1 1 0 Autophagy protein 16 (ATG16) Sec20 PF03908.8 EGC31855.1 - 0.01 15.4 2.6 0.086 12.5 0.7 2.7 2 1 0 2 2 2 0 Sec20 P4Ha_N PF08336.6 EGC31855.1 - 0.024 14.4 6.8 5 6.9 1.6 3.1 1 1 2 3 3 3 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Translin PF01997.11 EGC31855.1 - 0.51 9.8 5.4 0.3 10.6 2.0 1.7 1 1 1 2 2 2 0 Translin family Vfa1 PF08432.5 EGC31855.1 - 1.1 9.2 11.2 2.1 8.3 7.8 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Spore_II_R PF09551.5 EGC31855.1 - 1.2 9.1 5.5 0.53 10.3 2.2 1.5 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) NIPSNAP PF07978.8 EGC31856.1 - 7.5e-16 57.9 0.0 7.3e-08 32.3 0.0 2.3 2 0 0 2 2 2 2 NIPSNAP ABA_GPCR PF12430.3 EGC31856.1 - 0.046 12.8 0.1 0.11 11.6 0.0 1.6 1 0 0 1 1 1 0 Abscisic acid G-protein coupled receptor FNIP PF05725.7 EGC31857.1 - 3e-11 43.0 38.2 3.1e-06 27.0 0.0 9.4 5 3 1 6 6 6 3 FNIP Repeat Formyl_trans_N PF00551.14 EGC31858.1 - 1.8e-47 161.2 0.0 2.1e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Formyl transferase Glyco_trans_4_2 PF13477.1 EGC31858.1 - 0.022 14.6 0.1 0.031 14.0 0.1 1.3 1 0 0 1 1 1 0 Glycosyl transferase 4-like FERM_M PF00373.13 EGC31859.1 - 1e-18 67.7 0.0 1e-18 67.7 0.0 3.3 3 1 0 3 3 3 1 FERM central domain FERM_N PF09379.5 EGC31859.1 - 9.1e-09 35.2 3.0 3.7e-08 33.2 0.5 2.9 2 0 0 2 2 2 1 FERM N-terminal domain LRR_6 PF13516.1 EGC31859.1 - 9.2e-09 34.4 57.5 0.031 14.3 0.1 13.1 15 0 0 15 15 15 5 Leucine Rich repeat LRR_4 PF12799.2 EGC31859.1 - 1.1e-07 31.2 47.7 1.9e-05 24.1 1.3 9.3 5 2 3 10 10 10 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC31859.1 - 0.078 13.0 27.7 5.2 7.4 0.0 11.1 11 1 0 11 11 11 0 Leucine Rich Repeat LRR_7 PF13504.1 EGC31859.1 - 4.5 7.9 18.8 18 6.1 0.0 8.5 10 0 0 10 10 10 0 Leucine rich repeat HAP2-GCS1 PF10699.4 EGC31861.1 - 7.5e-19 67.4 0.4 1.9e-18 66.1 0.2 1.7 1 0 0 1 1 1 1 Male gamete fusion factor PAT1 PF09770.4 EGC31862.1 - 0.35 9.0 34.3 0.43 8.7 23.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 AAA_23 PF13476.1 EGC31862.1 - 0.42 10.9 18.6 0.66 10.2 12.9 1.4 1 0 0 1 1 1 0 AAA domain UPF0564 PF10595.4 EGC31862.1 - 1.2 8.0 31.7 1.6 7.5 22.0 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0564 P12 PF12669.2 EGC31862.1 - 7.6 6.8 7.8 14 5.9 5.4 1.4 1 0 0 1 1 1 0 Virus attachment protein p12 family DUF1900 PF08954.6 EGC31863.1 - 0.00055 19.4 0.0 0.00082 18.9 0.0 1.3 1 1 0 1 1 1 1 Domain of unknown function (DUF1900) FNIP PF05725.7 EGC31864.1 - 3.4e-152 494.2 99.2 5.7e-16 58.1 1.8 13.3 8 2 2 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC31864.1 - 0.0026 17.6 36.3 1.5 8.8 0.1 11.6 3 3 14 17 17 17 5 Protein of unknown function (DUF1769) Plus-3 PF03126.13 EGC31866.1 - 4.7e-26 90.9 0.0 4.7e-26 90.9 0.0 2.4 3 0 0 3 3 3 1 Plus-3 domain NADH_B2 PF14813.1 EGC31867.1 - 0.0046 16.5 1.6 0.005 16.4 1.1 1.1 1 0 0 1 1 1 1 NADH dehydrogenase 1 beta subcomplex subunit 2 ABC_membrane PF00664.18 EGC31868.1 - 3e-50 171.1 10.2 4.3e-50 170.6 7.0 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGC31868.1 - 5.4e-32 110.9 0.0 1.6e-31 109.4 0.0 1.8 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGC31868.1 - 1.2e-06 27.9 0.0 1.6e-06 27.4 0.0 1.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EGC31868.1 - 0.00028 20.5 0.0 0.0019 17.8 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGC31868.1 - 0.013 14.8 0.8 0.16 11.3 0.6 2.1 1 1 0 1 1 1 0 AAA domain AAA_21 PF13304.1 EGC31868.1 - 0.017 15.0 2.8 0.17 11.8 0.0 2.6 2 1 1 3 3 3 0 AAA domain AAA_17 PF13207.1 EGC31868.1 - 0.02 15.6 0.0 0.042 14.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGC31868.1 - 0.022 14.6 0.2 0.15 12.0 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EGC31868.1 - 0.074 13.2 0.2 0.39 10.9 0.1 2.1 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_18 PF13238.1 EGC31868.1 - 0.081 13.2 0.1 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain PRK PF00485.13 EGC31868.1 - 0.09 12.3 0.1 0.18 11.3 0.1 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family OTU PF02338.14 EGC31869.1 - 8.1e-14 52.2 0.1 1e-13 51.9 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease DUF4274 PF14096.1 EGC31869.1 - 0.054 13.3 0.1 0.085 12.6 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4274) OTU PF02338.14 EGC31870.1 - 1.3e-14 54.7 0.1 1.7e-14 54.4 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease YhhN PF07947.9 EGC31872.1 - 1.4e-41 141.9 21.7 1.4e-41 141.9 15.0 1.4 2 0 0 2 2 2 1 YhhN-like protein Mito_carr PF00153.22 EGC31873.1 - 6.3e-70 230.9 1.7 7.5e-27 92.8 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1632 PF07857.7 EGC31873.1 - 0.0033 16.7 0.1 1.3 8.2 0.0 2.5 2 0 0 2 2 2 2 CEO family (DUF1632) AAT PF03417.11 EGC31874.1 - 0.0054 16.1 0.0 0.0081 15.6 0.0 1.5 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RAI1 PF08652.6 EGC31875.1 - 0.049 13.4 0.4 0.32 10.7 0.0 2.3 1 1 1 2 2 2 0 RAI1 like PD-(D/E)XK nuclease His_Phos_2 PF00328.17 EGC31876.1 - 9.4e-36 123.8 0.0 1.5e-35 123.1 0.0 1.3 1 1 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Exo_endo_phos PF03372.18 EGC31877.1 - 1.1e-22 81.2 0.0 1.1e-22 81.2 0.0 1.5 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Ribonuc_P_40 PF08584.6 EGC31878.1 - 4.2e-48 163.7 0.0 7.4e-48 162.9 0.0 1.4 1 0 0 1 1 1 1 Ribonuclease P 40kDa (Rpp40) subunit Acetyltransf_13 PF13880.1 EGC31879.1 - 5.7e-27 93.2 0.0 1.3e-26 92.1 0.0 1.6 1 0 0 1 1 1 1 ESCO1/2 acetyl-transferase zf-C2H2_3 PF13878.1 EGC31879.1 - 1.2e-15 56.7 1.3 2.2e-15 55.9 0.9 1.5 1 0 0 1 1 1 1 zinc-finger of acetyl-transferase ESCO Acetyltransf_7 PF13508.1 EGC31879.1 - 7.4e-05 22.8 0.0 0.00014 21.9 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC31879.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family BRCT PF00533.21 EGC31880.1 - 0.026 14.6 0.2 0.13 12.4 0.0 2.3 2 0 0 2 2 2 0 BRCA1 C Terminus (BRCT) domain bZIP_1 PF00170.16 EGC31880.1 - 1.7 8.6 13.3 1.1 9.2 0.2 4.1 2 1 0 3 3 3 0 bZIP transcription factor DUF2681 PF10883.3 EGC31880.1 - 3.7 7.8 10.5 1 9.5 2.8 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) bZIP_2 PF07716.10 EGC31880.1 - 6.7 6.6 11.6 2.4 8.0 0.7 3.7 3 0 0 3 3 3 0 Basic region leucine zipper Apolipo_F PF15148.1 EGC31881.1 - 0.035 13.4 2.2 0.099 11.9 1.5 1.7 1 0 0 1 1 1 0 Apolipoprotein F DUF2877 PF11392.3 EGC31881.1 - 0.5 10.5 2.2 1.3 9.2 1.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2877) PALP PF00291.20 EGC31883.1 - 1.7e-62 211.4 0.0 2.2e-62 211.0 0.0 1.2 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme CBS PF00571.23 EGC31883.1 - 2.3e-16 59.2 0.0 8.7e-11 41.4 0.0 2.7 2 1 0 2 2 2 2 CBS domain Methyltransf_31 PF13847.1 EGC31884.1 - 3e-13 49.6 0.0 7.3e-13 48.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC31884.1 - 1e-10 42.1 0.0 2.2e-10 41.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain PRMT5 PF05185.11 EGC31884.1 - 3.3e-10 39.4 0.1 4.4e-10 39.0 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EGC31884.1 - 2.2e-09 36.8 0.1 3.7e-09 36.1 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC31884.1 - 3.6e-08 33.4 0.0 6e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC31884.1 - 1.5e-07 31.8 0.0 4.6e-07 30.2 0.0 1.9 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC31884.1 - 2.6e-07 30.5 0.0 6.8e-07 29.1 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGC31884.1 - 6e-07 28.4 0.1 8.9e-07 27.8 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGC31884.1 - 7.5e-07 29.4 0.1 1.4e-05 25.3 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGC31884.1 - 2e-06 27.3 0.0 2.9e-06 26.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain CMAS PF02353.15 EGC31884.1 - 8.8e-06 24.9 0.0 1.3e-05 24.4 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase FtsJ PF01728.14 EGC31884.1 - 6.5e-05 22.9 0.0 0.00012 22.0 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_16 PF10294.4 EGC31884.1 - 0.00026 20.4 0.2 0.00026 20.4 0.1 1.7 2 0 0 2 2 2 1 Putative methyltransferase Ubie_methyltran PF01209.13 EGC31884.1 - 0.00045 19.3 0.1 0.0007 18.7 0.1 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGC31884.1 - 0.00072 19.9 0.0 0.0016 18.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGC31884.1 - 0.00095 18.7 0.2 0.0015 18.0 0.2 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 PCMT PF01135.14 EGC31884.1 - 0.002 17.7 0.0 0.0032 17.0 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EGC31884.1 - 0.0098 15.0 0.3 0.03 13.5 0.2 1.9 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_24 PF13578.1 EGC31884.1 - 0.046 14.5 0.0 0.11 13.3 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain DUF2171 PF09939.4 EGC31885.1 - 0.037 14.0 0.1 0.085 12.8 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2171) DUF836 PF05768.9 EGC31886.1 - 2.6e-11 43.6 0.0 3.2e-11 43.3 0.0 1.1 1 0 0 1 1 1 1 Glutaredoxin-like domain (DUF836) Glutaredoxin PF00462.19 EGC31886.1 - 0.075 13.0 0.1 0.15 12.0 0.1 1.6 1 1 0 1 1 1 0 Glutaredoxin Thioredoxin_2 PF13098.1 EGC31886.1 - 0.11 12.6 0.0 0.12 12.5 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain GTP_EFTU PF00009.22 EGC31887.1 - 8.8e-57 191.5 0.3 1.6e-56 190.7 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGC31887.1 - 3.8e-27 93.9 0.1 9.9e-27 92.6 0.1 1.8 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGC31887.1 - 6.5e-18 64.3 1.6 3.8e-17 61.9 0.0 2.8 2 0 0 2 2 2 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGC31887.1 - 6.4e-13 48.6 1.5 3.1e-12 46.4 0.2 2.7 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGC31887.1 - 1.3e-09 37.6 0.0 3.9e-09 36.1 0.0 1.8 1 0 0 1 1 1 1 Elongation factor G, domain IV MMR_HSR1 PF01926.18 EGC31887.1 - 0.0074 16.2 0.1 0.027 14.4 0.0 2.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF148 PF02520.12 EGC31887.1 - 0.04 13.7 0.1 0.12 12.1 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function DUF148 TAP_C PF03943.8 EGC31888.1 - 1.1e-07 31.1 1.8 1.8e-07 30.4 1.2 1.4 1 0 0 1 1 1 1 TAP C-terminal domain NTF2 PF02136.15 EGC31888.1 - 0.0012 19.2 0.1 0.011 16.1 0.0 2.1 1 1 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain DUF2451 PF10474.4 EGC31889.1 - 1.8e-74 250.4 0.3 1.8e-74 250.4 0.2 2.8 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) DUF2450 PF10475.4 EGC31889.1 - 8.2e-63 212.0 6.4 1.6e-52 178.2 0.5 2.9 1 1 1 2 2 2 2 Protein of unknown function N-terminal domain (DUF2450) VHS PF00790.14 EGC31889.1 - 0.061 12.9 4.1 4.7 6.8 0.5 2.9 2 0 0 2 2 2 0 VHS domain Anoctamin PF04547.7 EGC31891.1 - 8.8e-100 334.4 21.5 1.1e-99 334.1 14.9 1.1 1 0 0 1 1 1 1 Calcium-activated chloride channel Cid2 PF09774.4 EGC31892.1 - 7.6e-09 35.8 7.3 0.00014 22.0 0.7 2.1 1 1 1 2 2 2 2 Caffeine-induced death protein 2 DUF413 PF04219.7 EGC31892.1 - 0.017 14.8 0.0 0.029 14.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF MRL1 PF13003.2 EGC31892.1 - 0.033 14.0 3.0 0.041 13.7 2.1 1.3 1 0 0 1 1 1 0 Ribosomal protein L1 TFCD_C PF12612.3 EGC31893.1 - 1.5e-23 83.2 2.6 1.6e-22 79.8 0.1 3.4 3 0 0 3 3 3 1 Tubulin folding cofactor D C terminal HEAT_EZ PF13513.1 EGC31893.1 - 3.2e-08 33.8 0.0 0.81 10.2 0.0 5.8 6 0 0 6 6 6 2 HEAT-like repeat HEAT PF02985.17 EGC31893.1 - 1.3e-06 27.9 0.0 0.13 12.4 0.0 5.0 5 0 0 5 5 5 2 HEAT repeat HEAT_2 PF13646.1 EGC31893.1 - 3.7e-05 23.9 0.0 6.2 7.1 0.0 4.6 3 1 1 4 4 4 2 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC31893.1 - 0.00044 20.5 2.1 0.41 11.0 0.0 5.5 3 3 3 6 6 6 1 Vacuolar 14 Fab1-binding region dUTPase PF00692.14 EGC31894.1 - 2.2e-43 146.7 0.0 2.6e-43 146.5 0.0 1.0 1 0 0 1 1 1 1 dUTPase TPR_2 PF07719.12 EGC31895.1 - 1.7e-21 74.3 1.3 0.0008 19.1 0.0 6.8 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31895.1 - 1.9e-20 72.2 11.1 4.9e-09 35.7 0.0 4.7 3 1 3 6 6 6 5 TPR repeat TPR_1 PF00515.23 EGC31895.1 - 1.6e-16 59.1 9.2 0.0052 16.3 0.1 6.9 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31895.1 - 1e-15 56.2 6.9 0.0011 18.5 0.1 7.6 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGC31895.1 - 2.2e-14 52.6 0.2 0.0028 18.1 0.0 5.9 4 1 2 6 6 5 4 Tetratricopeptide repeat Apc3 PF12895.2 EGC31895.1 - 9.4e-11 41.7 6.0 3.6e-07 30.2 0.2 4.7 4 0 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGC31895.1 - 1.3e-09 38.2 1.0 0.0003 21.0 0.0 4.7 4 1 0 5 5 4 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC31895.1 - 1.5e-09 37.6 2.3 0.0014 18.5 0.0 5.3 4 1 1 5 5 5 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGC31895.1 - 1.6e-09 38.1 0.0 1.7e-05 25.3 0.0 4.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC31895.1 - 9.1e-08 31.7 2.5 0.14 12.3 0.0 5.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31895.1 - 1.8e-07 30.4 1.1 2 8.4 0.0 6.0 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGC31895.1 - 0.0001 21.4 1.7 0.35 9.9 0.3 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC31895.1 - 0.0002 21.5 3.9 8.1 7.1 0.0 5.7 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC31895.1 - 0.0018 18.0 0.1 0.086 12.6 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC31895.1 - 0.0067 16.3 0.2 2.3 8.2 0.1 3.3 3 0 0 3 3 2 1 Tetratricopeptide repeat Apc5 PF12862.2 EGC31895.1 - 0.019 14.7 0.2 9.2 6.1 0.0 3.9 2 2 1 3 3 3 0 Anaphase-promoting complex subunit 5 Peptidase_M41 PF01434.13 EGC31896.1 - 3.9e-68 229.0 4.0 9.3e-68 227.8 2.8 1.6 1 1 0 1 1 1 1 Peptidase family M41 AAA PF00004.24 EGC31896.1 - 4.9e-43 146.4 0.0 1.1e-42 145.3 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC31896.1 - 9.9e-07 28.5 0.0 4.2e-06 26.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGC31896.1 - 3.5e-06 26.2 0.0 9.9e-06 24.7 0.0 1.7 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC31896.1 - 4.4e-05 23.6 2.5 0.0072 16.4 0.3 3.3 2 1 0 2 2 1 1 AAA domain AAA_16 PF13191.1 EGC31896.1 - 0.0001 22.3 0.3 0.0094 15.9 0.1 2.7 2 1 1 3 3 3 1 AAA ATPase domain Zeta_toxin PF06414.7 EGC31896.1 - 0.00096 18.3 0.4 0.0052 15.9 0.0 2.3 3 0 0 3 3 3 1 Zeta toxin AAA_19 PF13245.1 EGC31896.1 - 0.0017 18.1 0.1 0.0067 16.1 0.1 2.0 1 0 0 1 1 1 1 Part of AAA domain KaiC PF06745.8 EGC31896.1 - 0.0019 17.3 0.4 0.21 10.6 0.0 2.9 2 1 1 3 3 3 1 KaiC TIP49 PF06068.8 EGC31896.1 - 0.0021 16.8 0.1 0.004 15.9 0.1 1.4 1 0 0 1 1 1 1 TIP49 C-terminus Sigma54_activ_2 PF14532.1 EGC31896.1 - 0.0032 17.5 0.0 0.013 15.5 0.0 2.0 2 0 0 2 2 1 1 Sigma-54 interaction domain AAA_14 PF13173.1 EGC31896.1 - 0.0076 16.1 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGC31896.1 - 0.0081 16.0 0.0 0.023 14.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGC31896.1 - 0.0081 15.5 0.0 0.018 14.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EGC31896.1 - 0.0099 15.5 1.2 0.039 13.5 0.1 2.4 3 0 0 3 3 3 1 NACHT domain Mg_chelatase PF01078.16 EGC31896.1 - 0.011 14.9 0.1 0.026 13.6 0.1 1.6 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_17 PF13207.1 EGC31896.1 - 0.011 16.5 0.2 0.081 13.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGC31896.1 - 0.012 15.0 0.6 0.17 11.2 0.2 2.3 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGC31896.1 - 0.013 14.9 0.0 0.042 13.3 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 EGC31896.1 - 0.041 12.7 0.0 0.11 11.3 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EGC31896.1 - 0.044 14.0 1.3 0.18 12.0 0.0 2.7 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EGC31896.1 - 0.08 12.8 0.5 0.67 9.8 0.2 2.4 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGC31896.1 - 0.082 12.5 0.1 0.17 11.5 0.1 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 OKR_DC_1_C PF03711.10 EGC31897.1 - 0.074 13.1 0.1 0.17 11.9 0.1 1.6 1 0 0 1 1 1 0 Orn/Lys/Arg decarboxylase, C-terminal domain zf-LYAR PF08790.6 EGC31898.1 - 1e-05 25.0 4.9 1e-05 25.0 3.4 2.5 2 0 0 2 2 2 1 LYAR-type C2HC zinc finger Glyco_hydro_25 PF01183.15 EGC31899.1 - 1.7e-14 54.0 0.2 1.8e-14 53.9 0.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 2OG-FeII_Oxy_2 PF13532.1 EGC31900.1 - 2.3e-25 89.5 0.0 2.8e-25 89.3 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TDH PF03347.8 EGC31900.1 - 0.015 14.8 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Vibrio thermostable direct hemolysin Secretin_N_2 PF07655.8 EGC31900.1 - 1.7 9.1 9.0 1.1 9.6 0.9 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain SE PF08491.5 EGC31901.1 - 6.4e-100 333.5 0.0 8.7e-100 333.0 0.0 1.2 1 0 0 1 1 1 1 Squalene epoxidase FAD_binding_3 PF01494.14 EGC31901.1 - 6.7e-14 51.7 0.0 2.6e-08 33.3 0.0 2.0 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGC31901.1 - 9.5e-06 24.7 0.0 0.0043 15.9 0.0 2.3 2 0 0 2 2 2 2 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGC31901.1 - 9.7e-06 24.6 0.5 0.0025 16.7 0.3 2.1 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EGC31901.1 - 7.9e-05 21.8 0.1 0.00016 20.8 0.0 1.5 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGC31901.1 - 0.00076 19.4 0.1 0.0012 18.8 0.1 1.4 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC31901.1 - 0.0024 17.8 0.3 0.0051 16.8 0.2 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Lycopene_cycl PF05834.7 EGC31901.1 - 0.018 14.0 0.1 0.24 10.2 0.1 2.2 2 0 0 2 2 2 0 Lycopene cyclase protein Trp_halogenase PF04820.9 EGC31901.1 - 0.021 13.4 0.2 16 3.9 0.1 3.0 2 1 0 3 3 3 0 Tryptophan halogenase GIDA PF01134.17 EGC31901.1 - 0.024 13.4 2.7 0.1 11.4 1.9 1.8 1 1 0 1 1 1 0 Glucose inhibited division protein A Shikimate_DH PF01488.15 EGC31901.1 - 0.041 13.9 0.0 0.11 12.5 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase GDI PF00996.13 EGC31901.1 - 0.045 12.0 0.0 0.085 11.1 0.0 1.3 1 0 0 1 1 1 0 GDP dissociation inhibitor HI0933_like PF03486.9 EGC31901.1 - 0.081 11.3 0.1 0.15 10.5 0.0 1.4 1 0 0 1 1 1 0 HI0933-like protein DBB PF14545.1 EGC31901.1 - 0.092 12.2 0.1 0.24 10.9 0.0 1.6 1 0 0 1 1 1 0 Dof, BCAP, and BANK (DBB) motif, Pyr_redox PF00070.22 EGC31901.1 - 0.092 13.1 0.1 0.24 11.8 0.1 1.8 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGC31901.1 - 0.14 11.7 0.2 0.8 9.3 0.1 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain DDE_3 PF13358.1 EGC31902.1 - 0.07 12.8 0.1 0.084 12.6 0.1 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease CRAL_TRIO_2 PF13716.1 EGC31903.1 - 0.051 13.4 0.7 0.13 12.1 0.1 1.8 2 0 0 2 2 2 0 Divergent CRAL/TRIO domain Y_phosphatase2 PF03162.8 EGC31903.1 - 0.089 12.1 0.1 0.14 11.4 0.1 1.4 1 1 0 1 1 1 0 Tyrosine phosphatase family FANCI_S4 PF14678.1 EGC31904.1 - 1.6e-40 138.8 9.1 1.6e-40 138.8 6.3 6.0 6 0 0 6 6 6 1 FANCI solenoid 4 FANCI_S2 PF14676.1 EGC31904.1 - 2.8e-37 128.0 14.0 6.1e-37 126.9 2.9 4.8 4 0 0 4 4 4 1 FANCI solenoid 2 FANCI_HD2 PF14680.1 EGC31904.1 - 4e-29 101.3 4.7 4e-29 101.3 3.2 3.4 3 0 0 3 3 3 1 FANCI helical domain 2 FANCI_S1 PF14675.1 EGC31904.1 - 1.4e-18 67.1 5.7 1.4e-18 67.1 4.0 2.4 2 0 0 2 2 2 1 FANCI solenoid 1 FANCI_HD1 PF14679.1 EGC31904.1 - 0.00025 20.6 0.6 0.01 15.5 0.0 3.8 2 0 0 2 2 2 1 FANCI helical domain 1 Adaptin_binding PF10199.4 EGC31905.1 - 0.18 12.0 6.5 0.23 11.7 4.5 1.4 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 DnaJ PF00226.26 EGC31906.1 - 6.5e-18 64.2 0.1 1.9e-17 62.7 0.1 1.9 1 0 0 1 1 1 1 DnaJ domain DUF3675 PF12428.3 EGC31906.1 - 0.07 13.3 0.0 0.14 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3675) Cas_Cmr5 PF09701.5 EGC31906.1 - 0.096 12.8 0.3 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 CRISPR-associated protein (Cas_Cmr5) RNA_pol_Rpb2_6 PF00562.23 EGC31907.1 - 1.7e-112 375.9 0.1 3.3e-112 375.0 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGC31907.1 - 4.5e-39 133.4 0.2 8.8e-39 132.5 0.2 1.5 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_3 PF04565.11 EGC31907.1 - 1.9e-25 88.4 0.0 3.9e-25 87.3 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_7 PF04560.15 EGC31907.1 - 3.7e-20 71.9 0.0 9e-20 70.7 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EGC31907.1 - 6.6e-19 68.0 0.0 1.5e-18 66.8 0.0 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpa2_4 PF06883.7 EGC31907.1 - 1.1e-16 60.5 0.5 4.3e-16 58.6 0.0 2.3 2 0 0 2 2 2 1 RNA polymerase I, Rpa2 specific domain RNA_pol_Rpb2_5 PF04567.12 EGC31907.1 - 0.00011 22.1 0.1 0.00028 20.8 0.1 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Sld5 PF05916.6 EGC31908.1 - 4.3e-17 62.3 0.3 4.3e-17 62.3 0.2 1.5 2 0 0 2 2 2 1 GINS complex protein EcoRII-C PF09019.6 EGC31908.1 - 0.0083 15.9 0.5 0.021 14.6 0.2 1.9 2 1 0 2 2 2 1 EcoRII C terminal MutS_III PF05192.13 EGC31908.1 - 0.048 13.4 0.3 0.063 13.0 0.2 1.1 1 0 0 1 1 1 0 MutS domain III Dimer_Tnp_hAT PF05699.9 EGC31909.1 - 5.3e-18 64.4 0.1 5.3e-18 64.4 0.1 1.0 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_6 PF13912.1 EGC31909.1 - 0.064 13.1 0.1 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 C2H2-type zinc finger DUF2572 PF10833.3 EGC31910.1 - 0.11 11.9 1.8 0.44 9.9 0.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) Inositol_P PF00459.20 EGC31911.1 - 3.8e-50 170.7 0.0 4.9e-50 170.3 0.0 1.2 1 0 0 1 1 1 1 Inositol monophosphatase family DNA_primase_lrg PF04104.9 EGC31911.1 - 0.021 14.1 0.1 0.046 13.0 0.0 1.6 2 0 0 2 2 2 0 Eukaryotic and archaeal DNA primase, large subunit TIG PF01833.19 EGC31914.1 - 3e-36 123.2 77.6 9.5e-09 35.1 6.3 11.2 10 2 2 12 12 12 7 IPT/TIG domain EGF_2 PF07974.8 EGC31914.1 - 0.002 18.2 13.8 0.0046 17.0 9.5 1.6 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC31914.1 - 0.0022 17.8 8.6 0.0055 16.6 5.9 1.7 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) Qn_am_d_aIII PF09099.5 EGC31914.1 - 0.024 14.9 0.0 4.6 7.6 0.0 2.9 2 0 0 2 2 2 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III hEGF PF12661.2 EGC31914.1 - 5.5 7.2 7.6 0.17 12.0 0.7 2.1 2 0 0 2 2 2 0 Human growth factor-like EGF zf-RING_2 PF13639.1 EGC31915.1 - 3.6e-07 29.9 11.7 6.1e-07 29.1 8.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC31915.1 - 4e-06 26.3 10.3 6.5e-06 25.7 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31915.1 - 8.7e-06 25.7 5.5 2e-05 24.6 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC31915.1 - 1.3e-05 25.0 7.2 2.8e-05 24.0 5.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC31915.1 - 0.00031 20.3 13.0 0.00065 19.2 9.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31915.1 - 0.044 13.5 11.4 0.086 12.5 7.9 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC31915.1 - 0.068 13.0 7.8 0.19 11.6 5.4 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF972 PF06156.8 EGC31916.1 - 0.041 14.2 10.9 0.23 11.8 0.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF972) Sec3_C_2 PF15278.1 EGC31916.1 - 2 8.5 5.6 4.1 7.6 0.7 2.9 2 1 1 3 3 3 0 Sec3 exocyst complex subunit V_ATPase_I PF01496.14 EGC31916.1 - 2.8 5.6 13.1 3.5 5.3 9.1 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AhpC-TSA PF00578.16 EGC31918.1 - 2.1e-43 146.9 0.0 2.5e-43 146.7 0.0 1.0 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC31918.1 - 2.3e-26 92.1 0.0 2.7e-26 91.8 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EGC31918.1 - 4.9e-05 23.3 0.0 7.2e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.1 EGC31918.1 - 0.022 14.7 0.0 0.03 14.2 0.0 1.3 1 0 0 1 1 1 0 AhpC/TSA antioxidant enzyme PAT1 PF09770.4 EGC31919.1 - 1.4e-18 66.6 0.3 1.4e-18 66.6 0.2 4.1 1 1 1 3 3 3 2 Topoisomerase II-associated protein PAT1 DUF3439 PF11921.3 EGC31919.1 - 0.013 15.1 16.9 0.014 15.1 1.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC31919.1 - 8.1 6.2 38.0 1.2 8.9 3.5 2.6 3 0 0 3 3 3 0 Mucin-like glycoprotein FancD2 PF14631.1 EGC31920.1 - 1.4e-94 317.4 35.6 3.1e-80 269.8 18.5 7.0 5 2 2 7 7 7 4 Fanconi anaemia protein FancD2 nuclease HEAT_2 PF13646.1 EGC31921.1 - 8.7e-13 48.3 2.7 0.38 11.0 0.0 8.6 7 2 1 8 8 8 4 HEAT repeats HEAT PF02985.17 EGC31921.1 - 1e-11 43.8 5.0 0.066 13.3 0.0 8.6 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EGC31921.1 - 0.00023 21.5 2.2 13 6.4 0.0 6.6 6 1 1 7 7 7 2 HEAT-like repeat ATP-synt_DE_N PF02823.11 EGC31922.1 - 2e-20 72.3 0.0 3e-20 71.7 0.0 1.3 1 0 0 1 1 1 1 ATP synthase, Delta/Epsilon chain, beta-sandwich domain DUF3045 PF11243.3 EGC31923.1 - 0.12 12.6 0.0 0.18 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) HHH_5 PF14520.1 EGC31925.1 - 0.0026 17.8 0.0 0.0048 17.0 0.0 1.4 1 0 0 1 1 1 1 Helix-hairpin-helix domain Tubulin_2 PF13809.1 EGC31925.1 - 0.034 13.0 4.5 0.041 12.8 3.1 1.1 1 0 0 1 1 1 0 Tubulin like DUF763 PF05559.6 EGC31925.1 - 0.045 12.6 0.4 0.053 12.4 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF763) Apis_Csd PF11671.3 EGC31925.1 - 0.51 10.1 11.0 0.71 9.6 7.6 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein DUF1390 PF07150.6 EGC31925.1 - 2.9 7.1 15.3 2.4 7.4 9.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1390) Presenilin PF01080.12 EGC31925.1 - 5.4 5.7 7.0 6.5 5.4 4.9 1.1 1 0 0 1 1 1 0 Presenilin HhH-GPD PF00730.20 EGC31926.1 - 2.3e-19 69.6 0.0 5.9e-17 61.9 0.0 2.5 2 0 0 2 2 2 2 HhH-GPD superfamily base excision DNA repair protein NUDIX_4 PF14815.1 EGC31926.1 - 9.7e-13 47.5 0.0 6.3e-12 44.9 0.0 2.1 1 1 0 1 1 1 1 NUDIX domain HHH PF00633.18 EGC31926.1 - 5.4e-06 25.8 0.1 1.3e-05 24.6 0.1 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif Nucleoplasmin PF03066.10 EGC31926.1 - 0.006 16.1 2.1 0.006 16.1 1.4 2.3 2 0 0 2 2 2 1 Nucleoplasmin EndIII_4Fe-2S PF10576.4 EGC31926.1 - 2.8 8.2 6.1 0.91 9.8 1.8 2.1 2 0 0 2 2 2 0 Iron-sulfur binding domain of endonuclease III Erf4 PF10256.4 EGC31928.1 - 0.42 10.4 3.1 1.9 8.3 1.4 2.0 1 1 1 2 2 2 0 Golgin subfamily A member 7/ERF4 family Ribosomal_L16 PF00252.13 EGC31930.1 - 2.1e-33 114.9 0.1 2.7e-33 114.5 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L16p/L10e SET PF00856.23 EGC31931.1 - 9.6e-13 48.7 0.1 7e-10 39.4 0.1 2.4 1 1 0 1 1 1 1 SET domain Ank_2 PF12796.2 EGC31931.1 - 0.00011 22.4 0.0 0.00024 21.4 0.0 1.6 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC31931.1 - 0.00021 21.2 0.0 0.0021 18.1 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeat Ank PF00023.25 EGC31931.1 - 0.0012 18.4 0.0 0.012 15.3 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat DUF3447 PF11929.3 EGC31931.1 - 0.01 15.6 1.1 0.39 10.5 0.0 2.8 1 1 1 2 2 2 1 Domain of unknown function (DUF3447) DUF3669 PF12417.3 EGC31931.1 - 0.013 15.2 0.2 0.025 14.2 0.1 1.5 1 0 0 1 1 1 0 Zinc finger protein Ank_4 PF13637.1 EGC31931.1 - 0.055 14.0 0.0 0.18 12.3 0.0 1.9 1 0 0 1 1 1 0 Ankyrin repeats (many copies) YmgB PF10798.3 EGC31931.1 - 0.056 13.2 0.0 0.17 11.7 0.0 1.8 1 0 0 1 1 1 0 Biofilm development protein YmgB/AriR DUF3430 PF11912.3 EGC31933.1 - 0.0013 18.6 58.1 0.083 12.7 10.6 4.0 1 1 3 4 4 4 3 Protein of unknown function (DUF3430) DUF1582 PF07621.6 EGC31933.1 - 0.17 11.8 1.1 17 5.5 0.0 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF1582) WD40 PF00400.27 EGC31934.1 - 1.8e-19 68.7 13.5 9.7e-08 31.6 0.4 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat Nup160 PF11715.3 EGC31934.1 - 0.00082 17.6 0.1 0.0021 16.3 0.0 1.7 1 1 0 1 1 1 1 Nucleoporin Nup120/160 DUF972 PF06156.8 EGC31934.1 - 0.0017 18.6 17.0 0.0017 18.6 11.8 2.2 3 0 0 3 3 3 1 Protein of unknown function (DUF972) Syntaxin-6_N PF09177.6 EGC31934.1 - 0.0074 16.6 9.5 0.0074 16.6 6.6 2.5 1 1 1 2 2 2 1 Syntaxin 6, N-terminal DUF1513 PF07433.6 EGC31934.1 - 0.0093 14.8 0.0 0.11 11.4 0.0 2.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1513) PQQ_2 PF13360.1 EGC31934.1 - 0.022 14.1 0.0 0.84 9.0 0.0 2.6 1 1 0 2 2 2 0 PQQ-like domain PQQ_3 PF13570.1 EGC31934.1 - 0.068 13.4 0.3 16 5.9 0.0 3.2 3 0 0 3 3 3 0 PQQ-like domain APG6 PF04111.7 EGC31934.1 - 0.11 11.5 21.3 0.2 10.6 14.8 1.4 1 0 0 1 1 1 0 Autophagy protein Apg6 IncA PF04156.9 EGC31934.1 - 0.16 11.5 19.5 0.3 10.6 13.5 1.4 1 0 0 1 1 1 0 IncA protein SPT6_acidic PF14632.1 EGC31934.1 - 0.2 11.8 9.1 0.43 10.7 6.3 1.6 1 0 0 1 1 1 0 Acidic N-terminal SPT6 zf-RING_2 PF13639.1 EGC31936.1 - 4.5e-07 29.5 9.0 4.5e-07 29.5 6.2 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGC31936.1 - 4.5e-06 26.2 11.2 4.5e-06 26.2 7.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC31936.1 - 1.3e-05 24.7 6.7 1.3e-05 24.7 4.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC31936.1 - 6.4e-05 22.9 3.5 6.4e-05 22.9 2.4 2.6 3 1 0 3 3 3 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC31936.1 - 0.00012 21.9 10.6 0.00035 20.5 7.4 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC31936.1 - 0.011 15.4 9.4 0.011 15.4 6.5 2.1 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC31936.1 - 0.038 13.8 8.1 0.14 12.1 5.6 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC31936.1 - 0.71 9.7 7.4 0.041 13.7 0.9 2.1 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 11 RING-H2 finger FNIP PF05725.7 EGC31937.1 - 6.2e-218 704.6 50.9 5.1e-14 51.9 0.0 14.3 3 2 13 19 19 19 19 FNIP Repeat ADH_zinc_N PF00107.21 EGC31937.1 - 0.0025 17.3 3.7 42 3.6 0.0 6.7 1 1 5 8 8 8 1 Zinc-binding dehydrogenase DUF3215 PF11503.3 EGC31937.1 - 0.063 12.9 0.0 2.1 8.0 0.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) SPT16 PF08644.6 EGC31938.1 - 0.05 13.4 4.8 0.072 12.9 3.4 1.3 1 0 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) Neur_chan_memb PF02932.11 EGC31938.1 - 1.4 8.6 4.8 1.7 8.4 3.4 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ATP-synt_E PF05680.7 EGC31938.1 - 1.7 8.6 5.5 3.2 7.7 3.8 1.4 1 0 0 1 1 1 0 ATP synthase E chain Methyltransf_15 PF09445.5 EGC31939.1 - 3.2e-34 117.8 0.2 4e-34 117.5 0.2 1.1 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase Methyltransf_26 PF13659.1 EGC31939.1 - 3.7e-06 26.9 0.0 5.1e-06 26.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC31939.1 - 0.00021 20.9 0.1 0.00054 19.5 0.0 1.6 1 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGC31939.1 - 0.00022 20.6 0.0 0.0003 20.2 0.0 1.1 1 0 0 1 1 1 1 Conserved hypothetical protein 95 UPF0020 PF01170.13 EGC31939.1 - 0.00042 19.9 0.0 0.00065 19.3 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 Methyltransf_25 PF13649.1 EGC31939.1 - 0.0033 17.7 0.0 0.0053 17.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGC31939.1 - 0.14 11.2 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Rtf2 PF04641.7 EGC31940.1 - 7.7e-74 248.1 10.4 9.2e-74 247.9 7.2 1.0 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_UBOX PF13445.1 EGC31940.1 - 0.081 12.6 1.0 0.29 10.8 0.7 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGC31940.1 - 0.23 11.2 1.6 0.44 10.3 1.1 1.5 1 0 0 1 1 1 0 zinc-RING finger domain Vps39_2 PF10367.4 EGC31940.1 - 0.5 10.5 6.0 0.54 10.4 0.1 2.6 1 1 1 2 2 2 0 Vacuolar sorting protein 39 domain 2 Mucin PF01456.12 EGC31940.1 - 1.4 8.6 13.3 2.2 8.0 9.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein tRNA_bind PF01588.15 EGC31941.1 - 0.079 12.8 0.4 0.22 11.4 0.0 1.7 1 1 1 2 2 2 0 Putative tRNA binding domain Antifungal_prot PF11402.3 EGC31941.1 - 2.7 8.2 5.6 7.3 6.8 0.8 2.1 1 1 1 2 2 2 0 Antifungal protein Acyl-CoA_dh_1 PF00441.19 EGC31942.1 - 7.7e-46 155.9 0.0 1.2e-45 155.3 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGC31942.1 - 2.5e-29 102.1 0.1 4.2e-29 101.4 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGC31942.1 - 1.3e-21 75.7 0.0 3.6e-21 74.4 0.0 1.8 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGC31942.1 - 2.7e-20 72.9 0.0 4.4e-20 72.2 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 EGC31942.1 - 0.12 11.7 0.0 0.19 11.1 0.0 1.2 1 0 0 1 1 1 0 Acyl-CoA oxidase Patatin PF01734.17 EGC31943.1 - 1.3e-17 64.4 0.0 2e-16 60.5 0.0 2.4 1 1 0 1 1 1 1 Patatin-like phospholipase PAH PF02671.16 EGC31944.1 - 0.00036 20.0 0.8 0.00036 20.0 0.5 1.6 2 0 0 2 2 2 1 Paired amphipathic helix repeat DUF1042 PF06294.6 EGC31944.1 - 0.24 10.9 1.3 0.37 10.3 0.9 1.3 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1042) DSPc PF00782.15 EGC31945.1 - 9.1e-28 96.4 0.1 1e-27 96.3 0.1 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC31945.1 - 7.2e-05 22.2 0.1 0.00046 19.5 0.1 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase p450 PF00067.17 EGC31946.1 - 8.6e-85 284.9 0.1 9.8e-85 284.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DNA_pol_B PF00136.16 EGC31947.1 - 2.3e-111 372.8 3.6 2.3e-111 372.8 2.5 2.4 4 0 0 4 4 4 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGC31947.1 - 1.4e-35 122.7 5.4 6.3e-35 120.5 3.8 2.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-DNA_Pol PF08996.5 EGC31947.1 - 1.5e-31 109.2 13.9 1.5e-31 109.2 9.6 3.0 3 0 0 3 3 3 1 DNA Polymerase alpha zinc finger ATG_C PF09333.6 EGC31948.1 - 2.2e-16 59.8 0.0 1.1e-15 57.4 0.0 2.2 2 0 0 2 2 2 1 ATG C terminal domain Rhomboid PF01694.17 EGC31949.1 - 7.8e-39 133.0 15.2 7.8e-39 133.0 10.5 1.8 2 0 0 2 2 2 1 Rhomboid family AgrB PF04647.10 EGC31949.1 - 0.031 13.3 6.1 0.011 14.8 2.1 1.7 2 0 0 2 2 2 0 Accessory gene regulator B DUF3815 PF12821.2 EGC31949.1 - 0.56 10.1 9.1 5.5 6.9 5.8 2.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3815) OHCU_decarbox PF09349.5 EGC31950.1 - 1.8e-37 129.1 0.0 3.7e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 OHCU decarboxylase Amidohydro_4 PF13147.1 EGC31950.1 - 3.4e-27 96.1 0.0 4.6e-27 95.7 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGC31950.1 - 1e-24 87.8 0.0 2.7e-24 86.4 0.0 1.6 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGC31950.1 - 1.9e-06 27.6 0.0 4.8e-06 26.2 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGC31950.1 - 2.3e-06 27.0 0.2 2.8e-05 23.5 0.0 2.4 2 1 0 2 2 2 1 Amidohydrolase family DUF3958 PF13125.1 EGC31950.1 - 0.012 15.4 0.3 0.063 13.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3958) Acetyltransf_3 PF13302.1 EGC31952.1 - 2.9e-14 53.4 0.0 3.7e-14 53.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC31952.1 - 0.013 15.4 0.0 0.028 14.3 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC31952.1 - 0.026 14.5 0.0 0.091 12.8 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family YoaP PF14268.1 EGC31952.1 - 0.064 12.5 0.4 0.28 10.4 0.1 2.0 2 0 0 2 2 2 0 YoaP-like FR47 PF08445.5 EGC31952.1 - 0.085 12.6 0.0 0.22 11.3 0.0 1.7 1 1 0 1 1 1 0 FR47-like protein Acetyltransf_7 PF13508.1 EGC31952.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC31952.1 - 0.15 11.9 0.0 0.36 10.7 0.0 1.6 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain RhoGEF PF00621.15 EGC31953.1 - 1.7e-31 109.4 8.0 2.6e-31 108.8 5.5 1.3 1 0 0 1 1 1 1 RhoGEF domain IQ PF00612.22 EGC31953.1 - 6.5e-06 25.3 0.3 1.2e-05 24.4 0.2 1.5 1 0 0 1 1 1 1 IQ calmodulin-binding motif Pkinase PF00069.20 EGC31954.1 - 2.2e-73 246.6 0.0 4.7e-73 245.5 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC31954.1 - 9.1e-47 159.2 0.0 1.5e-46 158.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EGC31954.1 - 5.8e-45 149.6 27.9 2.8e-08 33.3 0.1 8.0 7 0 0 7 7 7 7 WD domain, G-beta repeat PB1 PF00564.19 EGC31954.1 - 1.1e-14 53.8 0.1 2.8e-14 52.5 0.1 1.7 1 0 0 1 1 1 1 PB1 domain F-box PF00646.28 EGC31954.1 - 3.4e-07 29.7 0.6 9.3e-07 28.3 0.4 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGC31954.1 - 8.6e-06 25.3 0.1 2e-05 24.1 0.1 1.7 1 0 0 1 1 1 1 F-box-like Kinase-like PF14531.1 EGC31954.1 - 1.9e-05 23.7 0.0 0.0012 17.9 0.0 2.5 2 1 0 2 2 2 1 Kinase-like Beta_helix PF13229.1 EGC31955.1 - 5.2e-05 23.0 34.4 5.2e-05 23.0 23.8 3.6 2 1 1 3 3 3 1 Right handed beta helix region Pex24p PF06398.6 EGC31956.1 - 1.3e-05 24.1 0.5 1.3e-05 24.1 0.3 3.5 1 1 3 4 4 4 1 Integral peroxisomal membrane peroxin Trypan_PARP PF05887.6 EGC31956.1 - 0.00049 19.9 34.9 0.00049 19.9 24.2 2.2 1 1 1 2 2 2 1 Procyclic acidic repetitive protein (PARP) Calcyon PF06387.6 EGC31956.1 - 0.011 15.1 1.0 0.011 15.1 0.7 2.0 2 0 0 2 2 2 0 D1 dopamine receptor-interacting protein (calcyon) Gaa1 PF04114.9 EGC31957.1 - 5.5e-21 74.8 23.4 5.5e-21 74.8 16.2 2.9 2 1 0 2 2 2 1 Gaa1-like, GPI transamidase component LIM PF00412.17 EGC31958.1 - 1.3e-12 47.5 5.8 2.1e-12 46.9 4.0 1.3 1 0 0 1 1 1 1 LIM domain DUF3005 PF11448.3 EGC31958.1 - 0.00058 19.4 6.2 0.011 15.2 0.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF3005) CDC37_C PF08564.5 EGC31958.1 - 0.02 14.7 0.3 8 6.3 0.0 2.8 2 0 0 2 2 2 0 Cdc37 C terminal domain BLOC1_2 PF10046.4 EGC31958.1 - 0.07 13.2 1.7 4 7.6 0.1 3.0 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 HasA PF06438.7 EGC31958.1 - 0.11 11.8 2.8 0.14 11.5 1.0 1.7 1 1 1 2 2 2 0 Heme-binding protein A (HasA) Creb_binding PF09030.5 EGC31958.1 - 0.12 12.5 3.6 28 4.9 0.1 3.9 1 1 3 4 4 4 0 Creb binding CBM_15 PF03426.9 EGC31958.1 - 0.22 10.8 10.5 2.5 7.4 0.6 2.8 1 1 1 2 2 2 0 Carbohydrate binding domain (family 15) KID PF02524.9 EGC31958.1 - 0.4 10.9 7.3 20 5.8 0.2 4.2 3 0 0 3 3 3 0 KID repeat PrcB_C PF14343.1 EGC31958.1 - 0.49 10.1 4.0 4 7.2 0.1 2.9 1 1 2 3 3 3 0 PrcB C-terminal Dicty_spore_N PF04562.7 EGC31959.1 - 2e-34 118.3 21.0 2e-34 118.3 14.6 5.4 2 1 2 5 5 5 1 Dictyostelium spore coat protein, N terminus Ribosomal_L28e PF01778.12 EGC31960.1 - 5.1e-28 97.8 0.2 5.1e-28 97.8 0.1 1.8 2 0 0 2 2 2 1 Ribosomal L28e protein family Mak16 PF04874.9 EGC31960.1 - 2.3e-13 50.0 27.1 2.3e-13 50.0 18.8 3.5 2 1 1 3 3 3 1 Mak16 protein C-terminal region zf-C3H1 PF10650.4 EGC31960.1 - 0.091 12.2 0.6 0.2 11.1 0.4 1.6 1 0 0 1 1 1 0 Putative zinc-finger domain Nop14 PF04147.7 EGC31960.1 - 0.29 9.0 26.3 0.37 8.6 18.2 1.2 1 0 0 1 1 1 0 Nop14-like family CDC45 PF02724.9 EGC31960.1 - 3 5.7 21.3 5.3 4.9 14.8 1.3 1 0 0 1 1 1 0 CDC45-like protein TauE PF01925.14 EGC31962.1 - 5.5e-25 88.2 17.6 1.8e-14 53.8 5.5 2.1 1 1 0 2 2 2 2 Sulfite exporter TauE/SafE PBP PF01161.15 EGC31963.1 - 3.7e-29 101.4 0.0 4.9e-29 101.0 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein Ras PF00071.17 EGC31965.1 - 1.1e-46 158.2 0.1 1.3e-46 157.9 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31965.1 - 9.4e-19 68.0 0.0 1.4e-18 67.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC31965.1 - 4.2e-14 52.1 0.1 4.8e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC31965.1 - 1.8e-09 37.0 0.1 2.2e-09 36.7 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC31965.1 - 6.7e-08 32.1 0.3 2e-07 30.6 0.2 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC31965.1 - 7.2e-05 22.0 0.1 0.00014 21.1 0.1 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC31965.1 - 0.00034 20.5 0.0 0.00069 19.5 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGC31965.1 - 0.0018 18.4 0.0 0.0046 17.1 0.0 1.8 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EGC31965.1 - 0.0019 17.6 0.1 0.9 8.9 0.0 2.2 1 1 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain G-alpha PF00503.15 EGC31965.1 - 0.0026 16.5 1.6 0.2 10.2 0.0 2.8 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.1 EGC31965.1 - 0.0029 17.6 0.0 0.0062 16.5 0.0 1.5 2 0 0 2 2 1 1 AAA ATPase domain FeoB_N PF02421.13 EGC31965.1 - 0.0082 15.4 0.2 0.21 10.8 0.0 2.5 2 1 1 3 3 3 1 Ferrous iron transport protein B AAA_17 PF13207.1 EGC31965.1 - 0.0087 16.8 0.7 1 10.2 0.3 2.6 2 1 0 2 2 2 1 AAA domain Septin PF00735.13 EGC31965.1 - 0.018 14.0 0.0 0.029 13.3 0.0 1.3 1 0 0 1 1 1 0 Septin CBM27 PF09212.5 EGC31965.1 - 0.031 14.2 0.2 2.4 8.1 0.0 2.2 2 0 0 2 2 2 0 Carbohydrate binding module 27 Arch_ATPase PF01637.13 EGC31965.1 - 0.048 13.3 0.1 0.068 12.8 0.0 1.3 1 1 0 1 1 1 0 Archaeal ATPase AAA_29 PF13555.1 EGC31965.1 - 0.05 13.1 0.1 0.1 12.1 0.1 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EGC31965.1 - 0.062 12.1 0.0 0.085 11.7 0.0 1.2 1 0 0 1 1 1 0 Type II/IV secretion system protein DUF2075 PF09848.4 EGC31965.1 - 0.064 12.2 0.0 0.13 11.2 0.0 1.4 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) Kp4 PF09044.5 EGC31965.1 - 0.069 12.9 0.1 0.15 11.8 0.0 1.6 1 1 0 1 1 1 0 Kp4 AAA_5 PF07728.9 EGC31965.1 - 0.13 11.9 0.0 0.31 10.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) Pkinase PF00069.20 EGC31966.1 - 3.1e-12 46.1 2.7 6.5e-11 41.8 0.0 2.7 2 1 1 3 3 3 1 Protein kinase domain Ribonuc_2-5A PF06479.7 EGC31966.1 - 6.7e-11 42.1 9.7 1.9e-07 30.9 6.7 2.4 1 1 0 1 1 1 1 Ribonuclease 2-5A Pkinase_Tyr PF07714.12 EGC31966.1 - 0.0002 20.5 0.7 0.0013 17.8 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Ku_N PF03731.10 EGC31966.1 - 0.02 14.3 5.4 0.021 14.2 1.6 2.2 1 1 1 2 2 2 0 Ku70/Ku80 N-terminal alpha/beta domain ERF PF04404.7 EGC31966.1 - 0.15 11.5 5.5 0.26 10.8 3.8 1.3 1 0 0 1 1 1 0 ERF superfamily DUF1765 PF08578.5 EGC31966.1 - 0.38 10.8 5.9 3.4 7.7 1.4 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1765) HEAT PF02985.17 EGC31967.1 - 0.00016 21.4 0.1 0.04 14.0 0.0 3.4 3 0 0 3 3 3 1 HEAT repeat HEAT_2 PF13646.1 EGC31967.1 - 0.00025 21.2 0.0 0.00089 19.4 0.0 1.9 1 1 0 1 1 1 1 HEAT repeats HEAT_EZ PF13513.1 EGC31967.1 - 0.0036 17.7 0.3 0.042 14.3 0.0 2.7 1 1 2 3 3 3 1 HEAT-like repeat Cnd1 PF12717.2 EGC31967.1 - 0.016 15.0 3.4 0.12 12.2 0.1 2.5 2 1 0 2 2 2 0 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGC31967.1 - 0.039 14.3 0.2 0.23 11.8 0.0 2.4 2 1 1 3 3 3 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGC31967.1 - 0.041 12.1 0.7 0.82 7.9 0.0 2.1 2 0 0 2 2 2 0 Adaptin N terminal region DUF3832 PF12909.2 EGC31967.1 - 0.1 12.6 0.0 0.22 11.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3832) KOW PF00467.24 EGC31968.1 - 3.5e-08 32.8 1.9 8.6e-08 31.6 1.3 1.7 1 0 0 1 1 1 1 KOW motif Josephin PF02099.12 EGC31969.1 - 1.1e-12 47.9 9.1 1.5e-11 44.1 6.3 2.1 1 1 0 1 1 1 1 Josephin DUF1883 PF08980.5 EGC31969.1 - 0.079 12.4 0.0 0.19 11.2 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1883) APG6 PF04111.7 EGC31970.1 - 6e-64 216.0 20.3 6e-64 216.0 14.1 2.3 2 0 0 2 2 2 1 Autophagy protein Apg6 Tim44 PF04280.10 EGC31971.1 - 0.082 12.8 0.2 0.16 11.9 0.1 1.5 1 0 0 1 1 1 0 Tim44-like domain TPR_1 PF00515.23 EGC31972.1 - 3.9e-06 26.2 1.0 1.1e-05 24.7 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC31972.1 - 0.00018 21.1 0.4 0.00095 18.9 0.0 2.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC31972.1 - 0.0018 17.9 0.1 0.0018 17.9 0.1 3.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC31972.1 - 0.0022 17.6 0.0 0.01 15.5 0.0 2.2 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC31972.1 - 0.0092 15.6 1.2 0.024 14.2 0.1 2.2 2 0 0 2 2 2 1 TPR repeat HSP70 PF00012.15 EGC31973.1 - 1.9e-273 907.8 10.6 2.2e-273 907.6 7.3 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGC31973.1 - 1.3e-14 53.6 0.2 3.5e-13 48.8 0.0 2.2 2 0 0 2 2 2 1 MreB/Mbl protein Hydantoinase_A PF01968.13 EGC31973.1 - 0.00015 20.9 0.1 0.0041 16.2 0.0 2.5 1 1 0 2 2 2 1 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EGC31973.1 - 0.00018 21.2 0.0 0.00052 19.6 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain DDR PF08841.5 EGC31973.1 - 0.0047 15.8 0.5 0.073 11.8 0.1 2.2 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Dict-STAT-coil PF09267.5 EGC31973.1 - 0.029 14.5 1.0 0.073 13.2 0.3 1.9 1 1 0 1 1 1 0 Dictyostelium STAT, coiled coil Rotamase PF00639.16 EGC31973.1 - 0.28 11.9 4.2 0.68 10.7 2.5 2.0 1 1 0 1 1 1 0 PPIC-type PPIASE domain Tetraspannin PF00335.15 EGC31974.1 - 1.5e-33 115.9 14.1 1.8e-33 115.6 9.8 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF1206 PF06724.6 EGC31974.1 - 8.3e-05 22.2 0.7 8.3e-05 22.2 0.5 2.1 2 1 1 3 3 3 1 Domain of Unknown Function (DUF1206) DUF2976 PF11190.3 EGC31974.1 - 0.00025 20.4 3.5 0.00025 20.4 2.4 2.8 2 1 1 3 3 3 1 Protein of unknown function (DUF2976) H_PPase PF03030.11 EGC31974.1 - 0.012 13.9 0.3 0.019 13.2 0.2 1.3 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase Ninjurin PF04923.7 EGC31974.1 - 0.022 14.4 6.1 1.2 8.9 0.5 2.4 1 1 1 2 2 2 0 Ninjurin 7TM_GPCR_Srz PF10325.4 EGC31974.1 - 1.2 8.1 12.5 0.087 11.9 3.9 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srz CcmH PF03918.9 EGC31974.1 - 1.9 7.4 6.6 0.35 9.8 0.3 2.6 1 1 2 3 3 3 0 Cytochrome C biogenesis protein DUF373 PF04123.8 EGC31974.1 - 2.1 7.3 8.8 0.51 9.3 3.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF2157 PF09925.4 EGC31974.1 - 4.8 6.7 0.0 4.8 6.7 0.0 3.1 2 1 0 2 2 2 0 Predicted membrane protein (DUF2157) DUF898 PF05987.8 EGC31974.1 - 8.5 5.1 11.6 4 6.2 5.9 1.9 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF898) DUF2890 PF11081.3 EGC31975.1 - 0.32 11.0 5.6 0.53 10.3 3.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) YfhO PF09586.5 EGC31975.1 - 5.7 4.8 5.1 5.8 4.7 3.6 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Phenol_hyd_sub PF06099.6 EGC31976.1 - 0.22 11.4 1.6 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Phenol hydroxylase subunit ATG13 PF10033.4 EGC31977.1 - 3.4e-25 88.8 2.1 1.6e-24 86.6 1.5 2.2 1 1 0 1 1 1 1 Autophagy-related protein 13 Ribosomal_S2 PF00318.15 EGC31978.1 - 6.4e-39 133.3 0.5 2.2e-18 66.2 0.0 2.1 1 1 1 2 2 2 2 Ribosomal protein S2 NIPSNAP PF07978.8 EGC31979.1 - 1.5e-17 63.4 0.0 1.7e-16 60.0 0.0 2.1 2 0 0 2 2 2 1 NIPSNAP RRM_2 PF04059.7 EGC31982.1 - 1.6e-26 92.1 0.5 1.7e-26 92.0 0.4 1.0 1 0 0 1 1 1 1 RNA recognition motif 2 RRM_6 PF14259.1 EGC31982.1 - 2.9e-05 23.9 0.1 3.6e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC31982.1 - 0.00013 21.4 0.4 0.00018 21.0 0.3 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) BRAP2 PF07576.7 EGC31982.1 - 0.013 15.0 2.1 0.013 15.0 1.4 1.3 1 1 0 1 1 1 0 BRCA1-associated protein 2 Smg4_UPF3 PF03467.10 EGC31982.1 - 0.049 13.6 0.6 0.054 13.4 0.4 1.1 1 0 0 1 1 1 0 Smg-4/UPF3 family 2Fe-2S_thioredx PF01257.14 EGC31982.1 - 0.068 12.7 0.1 0.074 12.6 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like [2Fe-2S] ferredoxin EBV-NA3 PF05009.7 EGC31983.1 - 0.023 13.9 5.1 0.022 14.0 1.0 2.4 2 1 1 3 3 3 0 Epstein-Barr virus nuclear antigen 3 (EBNA-3) BTV_NS2 PF04514.7 EGC31983.1 - 0.27 10.0 6.0 0.4 9.5 4.1 1.2 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 DUF2457 PF10446.4 EGC31983.1 - 0.89 8.2 12.9 1.6 7.3 8.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nucleoplasmin PF03066.10 EGC31983.1 - 1.4 8.4 13.6 3.1 7.2 9.5 1.5 1 0 0 1 1 1 0 Nucleoplasmin TFIIA PF03153.8 EGC31983.1 - 2 8.2 11.6 3.5 7.4 8.0 1.4 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit NOA36 PF06524.7 EGC31983.1 - 4.9 6.3 8.8 10 5.2 6.1 1.5 1 0 0 1 1 1 0 NOA36 protein DUF544 PF04424.8 EGC31984.1 - 2.5e-25 88.6 0.3 8.9e-25 86.8 0.2 2.0 1 0 0 1 1 1 1 Protein of unknown function (DUF544) DNA_pol_A_exo1 PF01612.15 EGC31985.1 - 0.088 12.2 0.1 0.16 11.3 0.1 1.5 1 0 0 1 1 1 0 3'-5' exonuclease DUF228 PF02989.9 EGC31987.1 - 0.14 11.7 0.0 0.19 11.2 0.0 1.2 1 0 0 1 1 1 0 Lyme disease proteins of unknown function Dict-STAT-coil PF09267.5 EGC31988.1 - 2e-45 153.6 15.0 3.6e-45 152.8 10.4 1.4 1 0 0 1 1 1 1 Dictyostelium STAT, coiled coil SH2 PF00017.19 EGC31988.1 - 1.4e-08 34.4 0.0 3.3e-08 33.1 0.0 1.7 1 0 0 1 1 1 1 SH2 domain DPPIV_N PF00930.16 EGC31989.1 - 1.3e-63 214.7 12.2 1.5e-63 214.5 6.7 1.9 1 1 0 2 2 2 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Peptidase_S9 PF00326.16 EGC31989.1 - 3.3e-45 153.9 0.0 7.2e-45 152.8 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S15 PF02129.13 EGC31989.1 - 2.7e-05 23.7 0.1 0.00032 20.2 0.0 2.2 1 1 1 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_5 PF12695.2 EGC31989.1 - 3.3e-05 23.6 0.0 6.4e-05 22.7 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGC31989.1 - 9.2e-05 21.9 0.0 0.00018 21.0 0.0 1.4 1 0 0 1 1 1 1 Putative esterase Abhydrolase_6 PF12697.2 EGC31989.1 - 0.0026 17.6 0.0 0.0044 16.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC31989.1 - 0.017 14.6 0.0 0.092 12.2 0.0 2.1 2 0 0 2 2 2 0 alpha/beta hydrolase fold Abhydrolase_2 PF02230.11 EGC31989.1 - 0.071 12.5 0.7 0.37 10.2 0.0 2.3 3 0 0 3 3 3 0 Phospholipase/Carboxylesterase DLH PF01738.13 EGC31989.1 - 0.12 11.5 0.0 2.6 7.2 0.0 2.3 2 0 0 2 2 2 0 Dienelactone hydrolase family Alba PF01918.16 EGC31990.1 - 4.3e-09 35.8 0.1 7.2e-09 35.1 0.1 1.4 1 0 0 1 1 1 1 Alba NAC PF01849.13 EGC31991.1 - 7.9e-16 57.3 0.1 2.4e-15 55.7 0.0 1.9 2 0 0 2 2 2 1 NAC domain E1-E2_ATPase PF00122.15 EGC31992.1 - 1.1e-21 76.9 0.3 3e-21 75.5 0.0 1.8 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EGC31992.1 - 6.1e-15 55.8 0.1 1.3e-14 54.8 0.1 1.6 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC31992.1 - 2.4e-14 54.2 2.2 4.6e-11 43.5 1.2 3.0 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC31992.1 - 2.3e-13 49.8 0.0 1.1e-12 47.7 0.0 2.1 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit NTF2 PF02136.15 EGC31993.1 - 4.7e-17 62.4 0.0 5.9e-17 62.1 0.0 1.1 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain Mtr2 PF10429.4 EGC31993.1 - 1.1e-05 25.2 0.0 1.5e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Nuclear pore RNA shuttling protein Mtr2 RRM_1 PF00076.17 EGC31994.1 - 8.5e-18 63.7 0.7 8.1e-11 41.4 0.0 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) FNIP PF05725.7 EGC31994.1 - 1.6e-15 56.7 19.8 1.4e-07 31.3 0.4 5.3 4 1 1 5 5 5 3 FNIP Repeat RRM_6 PF14259.1 EGC31994.1 - 3.3e-13 49.3 0.1 1.1e-06 28.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC31994.1 - 9.6e-11 41.3 1.4 1e-09 38.1 0.1 2.4 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC31994.1 - 0.018 14.8 0.3 3.2 7.6 0.0 3.4 2 1 1 3 3 3 0 RNA binding motif ArfGap PF01412.13 EGC31995.1 - 3.9e-40 136.2 0.0 3.9e-40 136.2 0.0 3.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf PH PF00169.24 EGC31995.1 - 1e-13 51.3 0.1 1e-13 51.3 0.1 3.8 3 0 0 3 3 3 1 PH domain BAR PF03114.13 EGC31995.1 - 4.5e-13 49.2 8.3 1.3e-12 47.7 5.8 1.8 1 0 0 1 1 1 1 BAR domain Ank_2 PF12796.2 EGC31995.1 - 1.9e-12 47.3 0.0 6.9e-12 45.5 0.0 1.9 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC31995.1 - 2.4e-10 40.6 0.0 3.2e-05 24.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC31995.1 - 2.4e-10 40.2 0.1 1.9e-07 31.0 0.0 2.6 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC31995.1 - 1.9e-09 36.8 0.0 0.0011 18.6 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeat Ank_3 PF13606.1 EGC31995.1 - 0.00019 21.3 0.0 1.2 9.6 0.0 2.9 2 0 0 2 2 2 2 Ankyrin repeat PH_11 PF15413.1 EGC31995.1 - 0.00061 20.0 0.1 0.00061 20.0 0.0 6.1 7 1 0 7 7 7 1 Pleckstrin homology domain Ras PF00071.17 EGC31996.1 - 1.9e-31 108.6 0.0 2.2e-31 108.4 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC31996.1 - 0.0032 17.9 0.0 0.0083 16.6 0.0 1.7 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EGC31996.1 - 0.01 15.3 0.0 0.01 15.3 0.0 1.1 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain DUF164 PF02591.10 EGC31996.1 - 0.074 12.8 0.1 0.22 11.3 0.0 1.8 1 0 0 1 1 1 0 Putative zinc ribbon domain DUF1510 PF07423.6 EGC31998.1 - 0.45 9.8 20.3 0.063 12.6 6.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) 7tm_2 PF00002.19 EGC31999.1 - 1.1e-09 37.7 22.5 1.5e-09 37.3 15.6 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGC31999.1 - 9.9e-09 34.5 28.8 1.4e-08 34.0 20.0 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 EGC31999.1 - 0.015 13.8 9.7 0.021 13.4 6.7 1.2 1 0 0 1 1 1 0 Ocular albinism type 1 protein Zip PF02535.17 EGC32000.1 - 9.9e-31 106.9 21.2 3.6e-24 85.3 0.3 3.0 1 1 1 3 3 3 3 ZIP Zinc transporter Ycf9 PF01737.12 EGC32000.1 - 0.018 14.4 0.1 0.052 12.9 0.1 1.9 1 0 0 1 1 1 0 YCF9 Acetyltransf_3 PF13302.1 EGC32001.1 - 4e-29 101.5 0.0 4.6e-29 101.3 0.0 1.0 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC32001.1 - 1.7e-12 47.5 0.6 2e-12 47.3 0.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC32001.1 - 3.5e-06 26.9 0.1 4.6e-06 26.5 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGC32001.1 - 0.0037 17.1 0.0 0.0064 16.3 0.0 1.5 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC32001.1 - 0.13 12.4 0.7 0.31 11.2 0.3 1.9 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain Amidase PF01425.16 EGC32002.1 - 1.5e-126 422.8 0.0 1.8e-126 422.5 0.0 1.0 1 0 0 1 1 1 1 Amidase Abhydrolase_5 PF12695.2 EGC32002.1 - 0.042 13.6 0.1 0.23 11.2 0.0 2.0 2 0 0 2 2 2 0 Alpha/beta hydrolase family DUF272 PF03312.10 EGC32003.1 - 0.013 15.7 1.2 0.014 15.6 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF272) zf-C3HC4 PF00097.20 EGC32004.1 - 5.3e-06 25.9 8.8 9.3e-06 25.2 6.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC32004.1 - 2.5e-05 24.0 6.0 4e-05 23.3 4.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC32004.1 - 8.8e-05 22.4 5.9 0.00015 21.7 4.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC32004.1 - 0.0003 20.3 5.7 0.00047 19.7 3.9 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC32004.1 - 0.0031 17.3 2.9 0.0081 16.0 2.0 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC32004.1 - 0.0041 16.8 8.0 0.0069 16.0 5.6 1.3 1 0 0 1 1 1 1 zinc-RING finger domain FYVE_2 PF02318.11 EGC32004.1 - 0.017 15.0 5.1 0.03 14.2 3.5 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger zf-MIZ PF02891.15 EGC32004.1 - 0.03 13.8 3.0 0.055 12.9 2.1 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-rbx1 PF12678.2 EGC32004.1 - 0.062 13.4 8.2 0.17 11.9 5.7 1.8 1 1 0 1 1 1 0 RING-H2 zinc finger Baculo_RING PF05883.6 EGC32004.1 - 0.099 12.4 5.1 0.22 11.3 3.5 1.5 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-RING_UBOX PF13445.1 EGC32004.1 - 0.19 11.4 4.3 0.56 9.9 3.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_4 PF14570.1 EGC32004.1 - 0.78 9.3 5.6 2 8.0 3.9 1.7 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain IBR PF01485.16 EGC32004.1 - 3.3 7.6 11.1 10 6.0 7.7 1.9 1 1 0 1 1 1 0 IBR domain DUF4448 PF14610.1 EGC32005.1 - 0.0035 16.8 0.3 0.011 15.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF4448) DUF912 PF06024.7 EGC32005.1 - 0.0045 17.0 0.0 0.0045 17.0 0.0 2.9 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Chlam_PMP PF02415.12 EGC32005.1 - 0.08 13.2 52.1 1.5 9.2 0.2 9.7 8 1 1 9 9 9 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat BUD22 PF09073.5 EGC32005.1 - 0.15 11.0 9.1 0.22 10.5 6.3 1.1 1 0 0 1 1 1 0 BUD22 Pex14_N PF04695.8 EGC32005.1 - 7.6 6.5 10.7 31 4.5 5.0 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EGF PF00008.22 EGC32005.1 - 8.7 6.4 14.4 0.061 13.2 2.6 2.8 3 0 0 3 3 3 0 EGF-like domain DUF914 PF06027.7 EGC32006.1 - 1.5e-101 339.6 24.5 1.6e-101 339.5 17.0 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF914) UAA PF08449.6 EGC32006.1 - 2.6e-08 33.1 24.1 3.6e-08 32.6 16.7 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGC32006.1 - 7.7e-08 32.4 32.3 0.00073 19.5 9.1 2.2 2 0 0 2 2 2 2 EamA-like transporter family TPT PF03151.11 EGC32006.1 - 1e-07 31.7 24.2 0.00037 20.1 8.9 2.5 2 0 0 2 2 2 2 Triose-phosphate Transporter family EmrE PF13536.1 EGC32006.1 - 0.00013 22.1 7.1 0.00013 22.1 4.9 3.1 2 1 1 3 3 3 1 Multidrug resistance efflux transporter Neurensin PF14927.1 EGC32007.1 - 0.099 12.0 0.0 0.099 12.0 0.0 1.1 1 0 0 1 1 1 0 Neurensin PWI PF01480.12 EGC32008.1 - 6.4e-24 83.8 0.0 1.1e-23 83.0 0.0 1.4 1 0 0 1 1 1 1 PWI domain PSCyt2 PF07583.6 EGC32008.1 - 0.0012 18.4 0.0 0.0013 18.2 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1549) PYC_OADA PF02436.13 EGC32008.1 - 0.1 12.0 0.1 0.25 10.7 0.0 1.6 1 1 1 2 2 2 0 Conserved carboxylase domain Pkinase PF00069.20 EGC32009.1 - 1e-69 234.6 0.0 1.4e-69 234.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32009.1 - 3.3e-51 173.8 0.0 4.9e-51 173.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC32009.1 - 3.5e-07 29.4 0.0 9.3e-05 21.5 0.0 2.3 2 0 0 2 2 2 2 Kinase-like DUF1241 PF06840.6 EGC32009.1 - 8.8e-07 28.3 0.1 3.1e-06 26.5 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1241) MCPVI PF02993.9 EGC32009.1 - 0.11 12.6 5.6 0.17 12.0 3.9 1.3 1 0 0 1 1 1 0 Minor capsid protein VI Menin PF05053.8 EGC32009.1 - 0.69 8.0 6.0 0.94 7.5 4.2 1.1 1 0 0 1 1 1 0 Menin TFIIF_alpha PF05793.7 EGC32009.1 - 1.3 7.2 9.1 1.9 6.7 6.3 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) FNIP PF05725.7 EGC32010.1 - 3.3e-28 97.3 35.5 2.5e-11 43.3 1.4 5.9 4 2 1 6 6 6 5 FNIP Repeat CBM49 PF09478.5 EGC32011.1 - 8e-16 57.9 0.4 1.1e-15 57.4 0.3 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Actin PF00022.14 EGC32012.1 - 6.4e-84 281.6 0.0 7.7e-84 281.3 0.0 1.1 1 0 0 1 1 1 1 Actin TnpV PF14198.1 EGC32012.1 - 0.017 14.9 0.0 0.056 13.3 0.0 1.9 1 0 0 1 1 1 0 Transposon-encoded protein TnpV MreB_Mbl PF06723.8 EGC32012.1 - 0.19 10.3 0.0 2.6 6.5 0.0 2.3 2 0 0 2 2 2 0 MreB/Mbl protein PCI PF01399.22 EGC32013.1 - 2.1e-16 60.1 1.9 2.1e-16 60.1 1.3 2.8 3 0 0 3 3 3 1 PCI domain Imm16 PF15565.1 EGC32013.1 - 0.01 15.7 2.9 0.61 9.9 0.1 3.3 2 1 1 3 3 3 0 Immunity protein 16 Transcrip_act PF04949.8 EGC32013.1 - 0.015 14.9 1.4 0.07 12.7 0.1 2.5 2 1 1 3 3 3 0 Transcriptional activator Pox_D2 PF04701.8 EGC32013.1 - 0.046 13.6 2.8 0.2 11.5 0.4 2.5 2 0 0 2 2 2 0 Pox virus D2 protein Hom_end_hint PF05203.11 EGC32013.1 - 2.3 7.8 6.3 6.5 6.4 2.5 2.3 1 1 0 1 1 1 0 Hom_end-associated Hint KTI12 PF08433.5 EGC32015.1 - 1.3e-10 41.0 16.4 2.1e-06 27.1 6.9 3.4 1 1 0 2 2 2 2 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGC32015.1 - 5.5e-05 23.9 0.9 0.00014 22.6 0.6 1.9 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC32015.1 - 0.00019 21.3 0.0 0.00073 19.4 0.0 2.2 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC32015.1 - 0.00062 19.6 1.1 0.00062 19.6 0.8 2.7 1 1 1 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC32015.1 - 0.0022 18.3 2.1 0.0022 18.3 1.5 2.8 1 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC32015.1 - 0.0053 16.9 0.3 0.019 15.0 0.1 2.1 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC32015.1 - 0.054 12.5 0.0 0.14 11.2 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA PF00004.24 EGC32015.1 - 0.078 13.1 0.1 0.21 11.8 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGC32015.1 - 0.17 11.6 0.0 0.3 10.8 0.0 1.3 1 0 0 1 1 1 0 Part of AAA domain CortBP2 PF09727.4 EGC32015.1 - 0.44 10.0 3.6 0.82 9.1 0.8 2.2 2 0 0 2 2 2 0 Cortactin-binding protein-2 Lipoprotein_6 PF01441.14 EGC32015.1 - 3.1 7.5 8.3 0.29 10.9 1.8 2.0 2 0 0 2 2 2 0 Lipoprotein Rep_fac_C PF08542.6 EGC32016.1 - 0.00057 19.8 0.1 0.007 16.3 0.0 2.5 2 1 0 2 2 2 1 Replication factor C C-terminal domain Imm13 PF15564.1 EGC32016.1 - 0.16 11.7 3.4 6.1 6.5 0.6 2.4 2 0 0 2 2 2 0 Immunity protein 13 Uricase PF01014.13 EGC32017.1 - 6.4e-63 210.9 3.0 5.1e-35 120.5 0.2 2.0 2 0 0 2 2 2 2 Uricase FliD_C PF07195.7 EGC32017.1 - 0.039 13.2 0.0 0.059 12.6 0.0 1.2 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 C-terminus RrnaAD PF00398.15 EGC32018.1 - 1.1e-37 129.5 2.0 5e-37 127.3 0.0 2.7 3 1 0 3 3 3 1 Ribosomal RNA adenine dimethylase Methyltransf_18 PF12847.2 EGC32018.1 - 0.027 15.0 1.2 0.09 13.3 0.0 2.4 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_32 PF13679.1 EGC32018.1 - 0.59 9.8 0.0 0.59 9.8 0.0 2.6 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32019.1 - 1.4e-25 89.6 0.0 2.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC32019.1 - 5.8e-20 71.5 0.0 1.1e-19 70.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC32019.1 - 1.1e-13 50.9 0.0 1.8e-13 50.1 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGC32019.1 - 8.3e-13 48.3 0.0 1.2e-12 47.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC32019.1 - 3.6e-12 46.5 0.0 6.7e-12 45.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC32019.1 - 4.4e-11 43.1 0.4 8.2e-10 39.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32019.1 - 1.4e-10 41.7 0.0 2.5e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC32019.1 - 5.1e-10 39.2 0.0 7.3e-10 38.7 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) CMAS PF02353.15 EGC32019.1 - 1.4e-06 27.5 0.0 2.1e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EGC32019.1 - 2.4e-06 27.0 0.0 4.3e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Pox_MCEL PF03291.11 EGC32019.1 - 3.7e-05 22.7 0.3 0.013 14.4 0.0 2.4 2 1 0 2 2 2 2 mRNA capping enzyme Methyltransf_26 PF13659.1 EGC32019.1 - 0.00014 21.8 0.0 0.00041 20.3 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC32019.1 - 0.0013 18.3 0.3 0.0056 16.3 0.2 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EGC32019.1 - 0.0022 17.3 0.0 0.0041 16.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_32 PF13679.1 EGC32019.1 - 0.0032 17.1 0.1 0.0098 15.5 0.0 1.8 1 1 1 2 2 2 1 Methyltransferase domain Fibrillarin PF01269.12 EGC32019.1 - 0.0077 15.1 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Fibrillarin DREV PF05219.7 EGC32019.1 - 0.0089 14.9 0.0 0.012 14.5 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase TPMT PF05724.6 EGC32019.1 - 0.012 15.0 0.0 0.021 14.2 0.0 1.5 1 0 0 1 1 1 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_29 PF03141.11 EGC32019.1 - 0.015 13.6 0.1 0.021 13.1 0.0 1.3 1 0 0 1 1 1 0 Putative S-adenosyl-L-methionine-dependent methyltransferase RrnaAD PF00398.15 EGC32019.1 - 0.059 12.4 0.0 0.086 11.8 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase HSP20 PF00011.16 EGC32020.1 - 4.9e-06 26.3 0.0 1.3e-05 25.0 0.0 1.7 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF4207 PF13904.1 EGC32020.1 - 4.7e-05 22.9 7.1 4.7e-05 22.9 4.9 2.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4207) Spheroidin PF05541.7 EGC32022.1 - 2.5e-17 61.8 3.3 3.8e-17 61.2 2.3 1.2 1 0 0 1 1 1 1 Entomopoxvirus spheroidin protein Abdominal-A PF12407.3 EGC32022.1 - 0.14 11.7 0.1 0.26 10.8 0.1 1.4 1 0 0 1 1 1 0 Homeobox protein Glyco_transf_10 PF00852.14 EGC32023.1 - 1.1e-52 178.7 1.4 1.9e-52 177.9 1.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 EGC32023.1 - 4.8e-12 46.3 0.2 3.5e-11 43.5 0.0 2.1 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily DUF1035 PF06281.7 EGC32023.1 - 5.9 6.7 6.2 4.2 7.2 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1035) TPR_11 PF13414.1 EGC32024.1 - 1.1e-36 124.3 40.4 2e-06 27.3 0.1 15.6 10 4 7 18 18 18 10 TPR repeat TPR_19 PF14559.1 EGC32024.1 - 2.4e-27 95.0 22.9 0.0005 20.3 0.0 15.3 13 3 2 16 16 16 6 Tetratricopeptide repeat TPR_14 PF13428.1 EGC32024.1 - 3.3e-25 86.2 0.0 0.012 16.2 0.0 13.8 15 2 2 17 17 13 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32024.1 - 3.7e-23 79.7 35.3 0.045 13.9 0.0 17.0 18 0 0 18 18 16 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32024.1 - 1.5e-21 74.4 37.7 0.0018 18.0 0.0 16.5 19 0 0 19 19 18 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32024.1 - 4.2e-21 75.0 0.0 0.089 13.5 0.0 12.4 13 1 1 14 14 13 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32024.1 - 2.1e-18 66.0 25.9 0.029 14.2 0.0 13.0 11 3 4 15 15 15 4 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32024.1 - 5.3e-18 63.3 53.7 0.032 13.9 0.2 16.9 17 1 1 18 18 14 7 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32024.1 - 3.4e-10 39.0 48.7 0.0044 16.5 0.1 14.3 17 0 0 17 17 16 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC32024.1 - 9.3e-10 38.5 45.4 0.0061 16.6 0.2 11.2 10 2 2 12 12 11 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGC32024.1 - 1.8e-09 36.6 8.5 7.4 6.6 0.0 12.5 14 1 1 15 15 13 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32024.1 - 2.5e-07 30.6 25.9 0.63 10.6 0.0 12.3 15 0 0 15 15 12 1 Tetratricopeptide repeat ChAPs PF09295.5 EGC32024.1 - 4.4e-06 25.7 24.7 9.9e-05 21.2 2.2 6.4 5 2 1 6 6 6 3 ChAPs (Chs5p-Arf1p-binding proteins) TPR_10 PF13374.1 EGC32024.1 - 0.00033 20.4 0.8 1.6 8.7 0.0 5.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_21 PF09976.4 EGC32024.1 - 0.0015 18.5 19.0 2.7 7.9 0.0 8.4 9 1 1 10 10 10 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC32024.1 - 0.061 13.2 18.8 2.4 8.0 0.0 7.8 8 1 0 8 8 8 0 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EGC32024.1 - 0.13 12.1 0.0 35 4.3 0.0 4.3 4 1 1 5 5 5 0 Tetratricopeptide repeat DUF2339 PF10101.4 EGC32026.1 - 0.0078 14.5 7.0 0.0095 14.2 4.9 1.0 1 0 0 1 1 1 1 Predicted membrane protein (DUF2339) RasGEF PF00617.14 EGC32027.1 - 1.7e-35 122.4 1.8 7.6e-35 120.3 0.8 2.6 2 0 0 2 2 2 1 RasGEF domain RhoGAP PF00620.22 EGC32027.1 - 4.1e-15 55.7 0.2 1.3e-14 54.0 0.1 1.9 1 0 0 1 1 1 1 RhoGAP domain RasGEF_N PF00618.15 EGC32027.1 - 2.2e-14 53.3 0.9 2.2e-14 53.3 0.6 3.1 2 0 0 2 2 2 1 RasGEF N-terminal motif E1-E2_ATPase PF00122.15 EGC32029.1 - 5.3e-23 81.2 0.0 5.3e-23 81.2 0.0 1.9 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EGC32029.1 - 3.5e-14 53.4 0.4 9.5e-14 52.0 0.3 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC32029.1 - 2.7e-13 50.8 0.0 7.4e-12 46.1 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC32029.1 - 8.5e-13 48.0 0.1 1.2e-10 41.2 0.0 2.6 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Nrap PF03813.9 EGC32030.1 - 0.0084 13.7 0.0 0.0093 13.5 0.0 1.0 1 0 0 1 1 1 1 Nrap protein OAS1_C PF10421.4 EGC32030.1 - 0.024 14.1 0.1 0.029 13.8 0.1 1.1 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus RNA_lig_T4_1 PF09511.5 EGC32031.1 - 5.2e-47 160.1 0.1 1e-46 159.1 0.1 1.5 2 0 0 2 2 2 1 RNA ligase zf-UBR PF02207.15 EGC32032.1 - 0.00028 20.5 11.9 0.00062 19.4 8.3 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF781 PF05612.7 EGC32033.1 - 2.9e-64 217.0 13.9 3.4e-64 216.7 9.6 1.0 1 0 0 1 1 1 1 Mouse protein of unknown function (DUF781) WD40 PF00400.27 EGC32034.1 - 8.1e-22 76.2 9.1 6.1e-06 25.9 0.0 5.6 5 0 0 5 5 5 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC32034.1 - 0.017 14.8 0.0 6.4 6.5 0.0 2.9 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Apc4_WD40 PF12894.2 EGC32034.1 - 0.027 13.9 0.3 14 5.3 0.0 3.6 4 0 0 4 4 4 0 Anaphase-promoting complex subunit 4 WD40 domain PQQ PF01011.16 EGC32034.1 - 0.14 11.7 0.6 3.9 7.1 0.1 2.8 2 0 0 2 2 2 0 PQQ enzyme repeat Myb_DNA-bind_6 PF13921.1 EGC32035.1 - 0.0018 18.3 0.8 0.0018 18.3 0.6 2.9 2 1 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGC32035.1 - 0.0063 16.5 1.8 0.026 14.5 1.2 2.1 1 1 0 1 1 1 1 Myb-like DNA-binding domain Endosulfine PF04667.12 EGC32036.1 - 9.3e-09 35.1 0.1 1.6e-08 34.4 0.1 1.4 1 1 0 1 1 1 1 cAMP-regulated phosphoprotein/endosulfine conserved region Ras PF00071.17 EGC32037.1 - 8.5e-59 197.5 0.1 1e-58 197.3 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32037.1 - 4.9e-16 59.3 0.0 9.4e-16 58.3 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC32037.1 - 1.1e-09 37.8 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC32037.1 - 2.4e-05 23.8 0.0 4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC32037.1 - 0.00059 19.7 0.0 0.00092 19.1 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase CBP4 PF07960.6 EGC32037.1 - 0.003 17.1 0.3 0.0069 15.9 0.2 1.5 2 0 0 2 2 2 1 CBP4 AAA_22 PF13401.1 EGC32037.1 - 0.012 15.7 0.4 0.18 11.9 0.0 2.5 2 1 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EGC32037.1 - 0.019 14.1 0.0 0.023 13.8 0.0 1.3 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EGC32037.1 - 0.026 13.7 0.1 0.068 12.4 0.1 1.8 1 1 0 1 1 1 0 Ferrous iron transport protein B Arch_ATPase PF01637.13 EGC32037.1 - 0.042 13.5 0.4 5.2 6.6 0.0 2.1 2 0 0 2 2 2 0 Archaeal ATPase DUF258 PF03193.11 EGC32037.1 - 0.046 12.8 0.2 0.081 12.1 0.1 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Septin PF00735.13 EGC32037.1 - 0.061 12.3 0.1 0.34 9.8 0.0 2.0 2 1 0 2 2 2 0 Septin IstB_IS21 PF01695.12 EGC32037.1 - 0.095 12.1 0.0 0.3 10.4 0.0 1.8 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_16 PF13191.1 EGC32037.1 - 0.11 12.4 0.0 4.3 7.2 0.0 2.7 3 0 0 3 3 3 0 AAA ATPase domain AAA PF00004.24 EGC32037.1 - 0.15 12.2 0.6 5.2 7.2 0.0 2.4 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EGC32037.1 - 2.4 6.7 6.9 1.8 7.1 0.0 2.9 1 1 2 3 3 3 0 G-protein alpha subunit DUF2663 PF10864.3 EGC32038.1 - 0.17 12.1 4.8 4.4 7.5 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF2663) FNIP PF05725.7 EGC32039.1 - 4.3e-66 218.6 62.1 4.8e-16 58.4 2.2 8.3 5 2 3 9 9 9 9 FNIP Repeat Terpene_synth PF01397.16 EGC32039.1 - 0.044 13.1 0.1 0.71 9.2 0.0 2.8 3 0 0 3 3 3 0 Terpene synthase, N-terminal domain RhoGEF PF00621.15 EGC32040.1 - 1.6e-46 158.4 1.8 1.6e-46 158.4 1.2 1.9 2 0 0 2 2 2 1 RhoGEF domain IQ PF00612.22 EGC32040.1 - 0.0014 18.0 0.3 0.003 17.0 0.2 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif WD40 PF00400.27 EGC32041.1 - 2.6e-16 58.7 1.9 3.1e-07 30.0 0.1 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGC32041.1 - 6.2e-05 21.4 0.0 0.0001 20.7 0.0 1.4 1 0 0 1 1 1 1 Cytochrome D1 heme domain OB_NTP_bind PF07717.11 EGC32042.1 - 2e-31 108.1 0.0 4.1e-31 107.1 0.0 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGC32042.1 - 9.1e-29 99.4 0.0 1.8e-28 98.5 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGC32042.1 - 8.5e-12 44.7 0.0 1.6e-11 43.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Vinculin PF01044.14 EGC32043.1 - 2.4e-43 148.3 52.8 4.8e-24 84.4 19.9 3.2 2 1 1 3 3 3 3 Vinculin family DNA_Packaging_2 PF11123.3 EGC32043.1 - 0.0027 17.5 1.1 0.56 10.1 0.0 3.3 3 0 0 3 3 3 1 DNA packaging protein LcrG PF07216.7 EGC32043.1 - 0.015 15.2 0.1 0.015 15.2 0.1 4.3 2 1 1 3 3 3 0 LcrG protein T2SF PF00482.18 EGC32043.1 - 0.096 12.5 0.5 0.77 9.6 0.3 2.6 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F DUF2357 PF09823.4 EGC32043.1 - 0.4 9.7 10.7 0.67 8.9 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF2357) PALP PF00291.20 EGC32044.1 - 2.5e-53 181.2 0.0 3.1e-53 181.0 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme LMBR1 PF04791.11 EGC32046.1 - 0.78 8.2 5.7 0.93 7.9 4.0 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF87 PF01935.12 EGC32046.1 - 1.7 8.4 14.1 2.1 8.1 9.8 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF87 ABC2_membrane_3 PF12698.2 EGC32046.1 - 2 7.3 19.7 2.3 7.1 13.6 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein eIF2A PF08662.6 EGC32047.1 - 1.2e-60 204.5 9.6 1.2e-57 194.7 3.0 4.5 2 1 3 5 5 5 3 Eukaryotic translation initiation factor eIF2A RRM_1 PF00076.17 EGC32047.1 - 0.009 15.6 0.0 0.042 13.4 0.0 2.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) HA2 PF04408.18 EGC32049.1 - 3.9e-26 91.0 2.0 9.8e-26 89.7 0.0 2.6 2 1 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGC32049.1 - 7.7e-24 83.7 0.0 1.9e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGC32049.1 - 3.2e-14 52.5 0.0 8.7e-14 51.1 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Allexi_40kDa PF05549.6 EGC32049.1 - 0.0016 17.7 0.2 0.0035 16.6 0.1 1.6 1 0 0 1 1 1 1 Allexivirus 40kDa protein PEPcase_2 PF14010.1 EGC32049.1 - 0.053 11.8 0.0 0.077 11.2 0.0 1.1 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase FmdE PF02663.9 EGC32049.1 - 0.1 12.4 1.0 3.6 7.4 0.0 2.6 2 0 0 2 2 2 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon Pyridoxal_deC PF00282.14 EGC32051.1 - 1.1e-72 244.6 0.0 1.4e-72 244.2 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain FAM86 PF14904.1 EGC32051.1 - 0.14 11.8 0.0 0.3 10.8 0.0 1.4 1 0 0 1 1 1 0 Family of unknown function OTU PF02338.14 EGC32052.1 - 8e-12 45.8 0.1 9.7e-12 45.5 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease ECSIT PF06239.6 EGC32052.1 - 0.086 11.6 0.0 0.16 10.7 0.0 1.4 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway DUF619 PF04768.8 EGC32053.1 - 1.9e-36 125.0 0.0 5.1e-36 123.6 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF619) AA_kinase PF00696.23 EGC32053.1 - 0.0026 17.3 0.1 0.012 15.1 0.1 2.3 1 1 1 2 2 2 1 Amino acid kinase family VID27 PF08553.5 EGC32054.1 - 7.8e-111 371.6 91.2 1.9e-93 314.1 5.5 3.6 1 1 1 2 2 2 2 VID27 cytoplasmic protein MMgT PF10270.4 EGC32055.1 - 1.3e-22 80.2 0.0 1.6e-22 79.9 0.0 1.1 1 0 0 1 1 1 1 Membrane magnesium transporter Guanylate_cyc PF00211.15 EGC32056.1 - 6.7e-61 204.8 0.0 1.2e-60 204.0 0.0 1.4 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain CHASE PF03924.8 EGC32056.1 - 2e-13 50.0 0.0 2.8e-13 49.5 0.0 1.3 1 0 0 1 1 1 1 CHASE domain ASFV_J13L PF05568.6 EGC32056.1 - 0.032 13.7 0.4 0.073 12.6 0.3 1.5 1 0 0 1 1 1 0 African swine fever virus J13L protein DUF2976 PF11190.3 EGC32056.1 - 0.46 10.0 2.3 0.36 10.3 0.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2976) FtsX PF02687.16 EGC32056.1 - 0.64 9.7 5.8 2.6 7.8 0.5 2.2 2 0 0 2 2 2 0 FtsX-like permease family Dickkopf_N PF04706.7 EGC32057.1 - 0.017 15.2 11.8 0.017 15.2 8.2 7.4 3 3 5 8 8 8 0 Dickkopf N-terminal cysteine-rich region EB PF01683.13 EGC32057.1 - 1.6 8.8 96.7 0.13 12.3 4.8 8.4 2 2 4 6 6 6 0 EB module ABC_tran PF00005.22 EGC32058.1 - 1.7e-54 183.8 0.1 8.4e-27 94.1 0.0 2.7 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGC32058.1 - 4.2e-54 183.8 70.4 5.8e-30 104.4 22.7 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGC32058.1 - 3.2e-16 60.1 26.1 1.3e-07 31.8 0.0 6.7 6 1 1 7 7 7 4 AAA domain AAA_29 PF13555.1 EGC32058.1 - 4.8e-05 22.8 1.8 0.023 14.2 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGC32058.1 - 7.7e-05 22.0 0.0 1.6 7.9 0.0 3.8 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 EGC32058.1 - 0.0025 17.3 1.8 1.4 8.3 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain SbcCD_C PF13558.1 EGC32058.1 - 0.0031 17.3 0.0 0.35 10.7 0.0 3.1 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EGC32058.1 - 0.01 15.2 0.1 1.5 8.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC32058.1 - 0.026 13.7 0.4 1.1 8.3 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC32058.1 - 0.12 12.2 0.3 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGC32058.1 - 0.58 10.4 15.0 0.2 11.9 0.2 3.4 4 0 0 4 4 4 0 AAA domain SAC3_GANP PF03399.11 EGC32059.1 - 2.8e-49 167.4 3.9 2.8e-49 167.4 2.7 3.4 3 1 1 4 4 4 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family Nup35_RRM_2 PF14605.1 EGC32059.1 - 0.15 11.8 0.0 0.38 10.5 0.0 1.8 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Dynein_light PF01221.13 EGC32061.1 - 1.5e-34 117.8 1.3 1.6e-34 117.7 0.9 1.0 1 0 0 1 1 1 1 Dynein light chain type 1 UCH PF00443.24 EGC32061.1 - 0.0086 15.2 0.2 0.0099 15.0 0.2 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Ground-like PF04155.13 EGC32061.1 - 0.0092 16.2 0.2 0.012 15.9 0.1 1.2 1 0 0 1 1 1 1 Ground-like domain ApoM PF11032.3 EGC32061.1 - 0.021 14.3 0.0 0.037 13.5 0.0 1.4 1 1 0 1 1 1 0 Apolipoprotein M (ApoM) Ectatomin PF06457.6 EGC32061.1 - 0.13 11.9 0.4 0.22 11.2 0.3 1.4 1 0 0 1 1 1 0 Ectatomin tRNA-synt_1b PF00579.20 EGC32062.1 - 8.5e-73 245.0 2.2 1.1e-72 244.6 1.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (W and Y) zf-CDGSH PF09360.5 EGC32063.1 - 5.5e-12 45.2 16.9 2.6e-07 30.3 2.2 2.9 3 0 0 3 3 3 2 Iron-binding zinc finger CDGSH type V-ATPase_H_N PF03224.9 EGC32065.1 - 3.6e-75 252.9 4.0 4.6e-75 252.6 1.7 1.8 2 0 0 2 2 2 1 V-ATPase subunit H V-ATPase_H_C PF11698.3 EGC32065.1 - 9.1e-46 154.6 3.3 2.2e-44 150.2 0.3 3.5 3 1 1 4 4 4 1 V-ATPase subunit H HEAT_2 PF13646.1 EGC32065.1 - 2.2e-05 24.6 0.0 0.043 14.0 0.0 2.8 2 0 0 2 2 2 2 HEAT repeats Arm PF00514.18 EGC32065.1 - 0.0021 17.8 0.5 4 7.4 0.1 3.3 2 0 0 2 2 2 2 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGC32065.1 - 0.044 13.8 0.0 0.18 11.9 0.0 2.1 1 0 0 1 1 1 0 HEAT repeat Cnd1 PF12717.2 EGC32065.1 - 0.14 11.9 8.1 4 7.2 0.1 3.8 3 2 0 3 3 3 0 non-SMC mitotic condensation complex subunit 1 Arm_2 PF04826.8 EGC32065.1 - 0.61 9.1 9.0 0.41 9.6 0.0 3.1 4 0 0 4 4 4 0 Armadillo-like Prp18 PF02840.10 EGC32066.1 - 5.6e-60 201.3 0.1 5.6e-60 201.3 0.1 3.1 3 1 0 3 3 3 1 Prp18 domain PRP4 PF08799.6 EGC32066.1 - 7.5e-15 53.8 0.4 1.3e-14 53.1 0.3 1.4 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Homeobox PF00046.24 EGC32067.1 - 2.2e-10 39.9 0.6 2.2e-10 39.9 0.4 2.9 3 0 0 3 3 3 1 Homeobox domain Cyclin_N PF00134.18 EGC32067.1 - 8.5e-09 35.0 0.5 8.5e-09 35.0 0.3 3.2 4 0 0 4 4 4 1 Cyclin, N-terminal domain Terminase_5 PF06056.7 EGC32067.1 - 0.014 14.9 0.0 0.038 13.5 0.0 1.8 1 0 0 1 1 1 0 Putative ATPase subunit of terminase (gpP-like) 7tm_3 PF00003.17 EGC32068.1 - 4e-33 114.7 33.7 7.9e-33 113.7 23.4 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR RhoGAP PF00620.22 EGC32069.1 - 1.5e-33 115.5 0.1 3e-33 114.5 0.0 1.5 1 0 0 1 1 1 1 RhoGAP domain Reg_prop PF07494.6 EGC32069.1 - 0.0022 17.7 4.5 6.8 7.0 0.0 5.8 6 1 0 6 6 6 2 Two component regulator propeller SapB_1 PF05184.10 EGC32070.1 - 4e-48 160.4 39.0 2.1e-10 40.1 0.5 6.9 6 1 0 6 6 6 5 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC32070.1 - 8.7e-45 150.2 26.4 1.7e-08 34.3 0.3 7.2 6 0 0 6 6 6 6 Saposin-like type B, region 2 zf-Mss51 PF13824.1 EGC32070.1 - 6.5e-05 22.7 1.7 8.9 6.2 0.0 4.6 4 0 0 4 4 4 2 Zinc-finger of mitochondrial splicing suppressor 51 DUF445 PF04286.7 EGC32070.1 - 0.00061 19.4 0.0 1.6 8.1 0.0 3.4 3 1 0 3 3 3 2 Protein of unknown function (DUF445) Phospholip_B PF04916.8 EGC32070.1 - 0.014 13.5 1.3 10 4.0 0.0 3.6 4 0 0 4 4 4 0 Phospholipase B cwf21 PF08312.7 EGC32070.1 - 0.029 14.1 0.4 1e+02 2.8 0.0 4.0 4 0 0 4 4 4 0 cwf21 domain zf-H2C2_5 PF13909.1 EGC32070.1 - 0.12 12.6 9.2 25 5.3 0.1 4.7 4 0 0 4 4 4 0 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EGC32070.1 - 0.12 12.6 8.8 51 4.4 0.0 4.8 4 0 0 4 4 4 0 Zinc-finger double domain RVT_3 PF13456.1 EGC32070.1 - 0.13 12.0 0.5 50 3.7 0.0 3.5 3 0 0 3 3 3 0 Reverse transcriptase-like HTH_23 PF13384.1 EGC32070.1 - 0.15 11.7 0.0 28 4.5 0.0 3.4 4 0 0 4 4 4 0 Homeodomain-like domain Rubis-subs-bind PF09273.6 EGC32070.1 - 0.94 9.3 3.7 50 3.8 0.0 3.6 4 0 0 4 4 4 0 Rubisco LSMT substrate-binding DUF4359 PF14271.1 EGC32070.1 - 0.97 9.8 6.2 85 3.5 0.0 4.8 5 0 0 5 5 5 0 Domain of unknown function (DUF4359) UQ_con PF00179.21 EGC32071.1 - 4.3e-45 152.5 0.5 4.9e-45 152.3 0.4 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGC32071.1 - 0.0014 18.5 1.2 0.0016 18.2 0.8 1.5 1 1 0 1 1 1 1 RWD domain Prok-E2_B PF14461.1 EGC32071.1 - 0.025 14.3 0.0 0.032 13.9 0.0 1.2 1 0 0 1 1 1 0 Prokaryotic E2 family B UEV PF05743.8 EGC32071.1 - 0.077 12.6 0.3 0.15 11.7 0.2 1.5 1 1 0 1 1 1 0 UEV domain 2Fe-2S_thioredx PF01257.14 EGC32072.1 - 1.1e-59 200.2 0.2 1.4e-59 199.8 0.2 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin FNIP PF05725.7 EGC32073.1 - 1.3e-32 111.4 57.3 9.8e-05 22.2 0.1 10.9 5 2 7 13 13 13 11 FNIP Repeat zf-B_box PF00643.19 EGC32073.1 - 2.3e-05 24.2 4.9 3.8e-05 23.4 3.4 1.4 1 0 0 1 1 1 1 B-box zinc finger Glyco_hydro_114 PF03537.8 EGC32073.1 - 5.5e-05 22.8 1.9 15 5.4 0.0 6.1 1 1 6 7 7 7 2 Glycoside-hydrolase family GH114 7TMR-HDED PF07697.6 EGC32073.1 - 0.2 11.3 7.1 0.32 10.7 4.9 1.2 1 0 0 1 1 1 0 7TM-HD extracellular zf-UBR PF02207.15 EGC32073.1 - 0.35 10.5 4.5 1.1 9.0 3.1 1.8 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) G8 PF10162.4 EGC32074.1 - 1.9e-31 108.4 0.1 1.9e-31 108.4 0.0 3.2 4 0 0 4 4 4 1 G8 domain Amnionless PF14828.1 EGC32074.1 - 0.27 9.6 1.5 0.28 9.6 0.0 1.7 2 0 0 2 2 2 0 Amnionless ETRAMP PF09716.5 EGC32074.1 - 0.42 10.5 4.3 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Sec1 PF00995.18 EGC32075.1 - 1.8e-104 350.4 0.1 3.2e-104 349.6 0.0 1.3 1 1 0 1 1 1 1 Sec1 family NAD_binding_6 PF08030.7 EGC32075.1 - 0.0066 16.3 0.5 0.016 15.1 0.4 1.7 1 0 0 1 1 1 1 Ferric reductase NAD binding domain RhoGAP PF00620.22 EGC32076.1 - 1.6e-27 96.0 0.2 1.1e-26 93.2 0.1 2.3 2 0 0 2 2 2 1 RhoGAP domain Tom22 PF04281.8 EGC32076.1 - 3.6 7.1 5.3 5.9 6.4 3.7 1.3 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 Inhibitor_I36 PF03995.8 EGC32077.1 - 6.6e-05 23.2 0.3 8.4e-05 22.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase inhibitor family I36 Crystall_3 PF08964.5 EGC32077.1 - 0.047 13.4 0.0 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Beta/Gamma crystallin Misat_Tub_SegII PF10644.4 EGC32078.1 - 8.2e-31 106.4 2.3 8.2e-31 106.4 1.6 2.5 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGC32078.1 - 3.1e-16 59.3 0.5 7.6e-16 58.0 0.4 1.6 1 1 0 1 1 1 1 Tubulin domain Tubulin PF00091.20 EGC32078.1 - 1.6e-07 31.3 2.3 1.6e-07 31.3 1.6 2.8 2 1 0 2 2 2 1 Tubulin/FtsZ family, GTPase domain AIM24 PF01987.12 EGC32079.1 - 5.6e-53 179.5 2.1 1.1e-52 178.6 1.5 1.5 2 0 0 2 2 2 1 Mitochondrial biogenesis AIM24 Abhydrolase_5 PF12695.2 EGC32080.1 - 8.5e-13 48.2 0.0 1.3e-12 47.7 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC32080.1 - 6.9e-08 32.3 0.9 3.8e-06 26.6 0.0 2.9 3 0 0 3 3 3 1 alpha/beta hydrolase fold SAM_2 PF07647.12 EGC32080.1 - 3.5e-06 26.7 0.2 7.1e-06 25.7 0.1 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Abhydrolase_6 PF12697.2 EGC32080.1 - 3.8e-06 26.9 0.0 8.6e-05 22.5 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family SAM_1 PF00536.25 EGC32080.1 - 6.3e-06 26.2 0.3 1.7e-05 24.8 0.2 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Peptidase_S9 PF00326.16 EGC32080.1 - 8.3e-06 25.1 0.1 0.00013 21.3 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGC32080.1 - 0.00017 21.1 0.4 0.012 15.0 0.0 2.5 1 1 1 2 2 2 1 Phospholipase/Carboxylesterase Ser_hydrolase PF06821.8 EGC32080.1 - 0.0021 17.6 0.0 0.0088 15.6 0.0 1.8 1 1 0 1 1 1 1 Serine hydrolase BAAT_C PF08840.6 EGC32080.1 - 0.0026 17.5 0.3 0.014 15.0 0.2 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal IncFII_repA PF02387.10 EGC32080.1 - 0.0066 15.6 0.1 0.01 15.0 0.1 1.2 1 0 0 1 1 1 1 IncFII RepA protein family DUF1749 PF08538.5 EGC32080.1 - 0.013 14.3 0.1 0.076 11.8 0.0 2.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1749) DLH PF01738.13 EGC32080.1 - 0.033 13.4 0.0 0.057 12.6 0.0 1.3 1 0 0 1 1 1 0 Dienelactone hydrolase family FSH1 PF03959.8 EGC32080.1 - 0.036 13.5 0.0 0.057 12.8 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Tetraspannin PF00335.15 EGC32081.1 - 8e-16 57.9 7.9 1.1e-15 57.5 5.5 1.1 1 0 0 1 1 1 1 Tetraspanin family DUF2306 PF10067.4 EGC32081.1 - 1.5e-05 25.0 5.7 1.6e-05 24.9 2.2 2.1 2 0 0 2 2 2 1 Predicted membrane protein (DUF2306) Wzy_C PF04932.10 EGC32081.1 - 0.21 11.3 10.3 0.023 14.5 3.0 2.1 2 1 0 2 2 2 0 O-Antigen ligase DUF872 PF05915.7 EGC32081.1 - 0.42 10.4 0.0 0.42 10.4 0.0 2.6 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF420 PF04238.7 EGC32081.1 - 0.53 10.2 9.3 0.18 11.7 2.3 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF420) Herpes_LMP1 PF05297.6 EGC32081.1 - 2.1 7.1 4.3 3.6 6.3 3.0 1.4 1 0 0 1 1 1 0 Herpesvirus latent membrane protein 1 (LMP1) UPF0093 PF03653.8 EGC32081.1 - 3.1 7.7 10.7 0.36 10.7 4.4 1.6 2 1 0 2 2 2 0 Uncharacterised protein family (UPF0093) DUF4064 PF13273.1 EGC32081.1 - 6.5 6.9 18.8 1.1 9.4 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Homeobox_KN PF05920.6 EGC32083.1 - 1.1e-13 50.6 0.1 1.5e-13 50.2 0.1 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGC32083.1 - 9.9e-12 44.3 0.1 1.1e-11 44.1 0.1 1.0 1 0 0 1 1 1 1 Homeobox domain DUF3567 PF12091.3 EGC32084.1 - 0.03 14.2 1.0 66 3.5 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3567) Microvir_lysis PF04517.7 EGC32084.1 - 0.11 12.2 6.5 3.5 7.4 0.1 3.6 3 0 0 3 3 3 0 Microvirus lysis protein (E), C terminus FNIP PF05725.7 EGC32085.1 - 7.2e-120 390.7 50.1 2.4e-16 59.3 0.1 9.1 9 0 0 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC32085.1 - 2.2 8.3 34.7 7.9 6.5 0.4 9.4 6 3 5 11 11 11 0 Protein of unknown function (DUF1769) Fz PF01392.17 EGC32086.1 - 0.1 12.9 8.2 0.095 13.0 3.5 2.2 2 0 0 2 2 2 0 Fz domain SR-25 PF10500.4 EGC32086.1 - 1.1 8.7 8.3 1.6 8.1 5.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein 2-Hacid_dh_C PF02826.14 EGC32087.1 - 7.4e-51 171.8 0.0 1.1e-50 171.2 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC32087.1 - 1.2e-29 102.4 0.0 1.4e-29 102.2 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC32087.1 - 3.6e-08 33.4 0.0 6.4e-08 32.6 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase GFO_IDH_MocA PF01408.17 EGC32087.1 - 0.00021 21.7 0.0 0.049 14.1 0.0 2.5 2 0 0 2 2 2 1 Oxidoreductase family, NAD-binding Rossmann fold Semialdhyde_dh PF01118.19 EGC32087.1 - 0.0049 17.1 0.2 3.9 7.8 0.1 2.7 2 1 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain AlaDh_PNT_N PF05222.10 EGC32087.1 - 0.058 13.4 0.0 0.93 9.4 0.0 2.3 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain RRM_1 PF00076.17 EGC32088.1 - 9e-11 41.2 0.4 1.7e-10 40.4 0.3 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC32088.1 - 2.9e-10 39.9 0.2 5e-10 39.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC32088.1 - 3.6e-10 39.5 0.2 6.6e-10 38.6 0.2 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EGC32088.1 - 4.5e-05 23.0 2.6 4.5e-05 23.0 1.8 2.3 2 0 0 2 2 2 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RRM_3 PF08777.6 EGC32088.1 - 0.0047 16.7 0.8 0.012 15.3 0.6 1.7 1 1 0 1 1 1 1 RNA binding motif zf-CCCH_2 PF14608.1 EGC32088.1 - 0.0061 16.5 2.7 0.015 15.3 1.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type FYVE PF01363.16 EGC32088.1 - 0.022 14.6 3.4 0.052 13.4 2.3 1.7 1 1 0 1 1 1 0 FYVE zinc finger Nup35_RRM_2 PF14605.1 EGC32088.1 - 0.041 13.6 0.0 0.072 12.8 0.0 1.4 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif CRAM_rpt PF07016.6 EGC32088.1 - 0.42 10.0 3.7 5.3 6.4 0.1 2.4 2 0 0 2 2 2 0 Cysteine-rich acidic integral membrane protein precursor Menin PF05053.8 EGC32088.1 - 1.4 6.9 5.1 2 6.5 3.5 1.2 1 0 0 1 1 1 0 Menin DUF3464 PF11947.3 EGC32088.1 - 2.1 7.8 7.8 5.2 6.5 4.6 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) DUF912 PF06024.7 EGC32088.1 - 5.2 7.1 7.4 16 5.6 5.1 1.8 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PQ-loop PF04193.9 EGC32090.1 - 5.8e-22 77.0 16.2 4.3e-17 61.4 0.4 3.6 4 0 0 4 4 4 2 PQ loop repeat DUF1275 PF06912.6 EGC32090.1 - 0.027 13.6 2.5 0.053 12.7 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1275) FUSC-like PF12805.2 EGC32090.1 - 0.061 12.2 6.0 0.25 10.2 0.8 2.4 2 0 0 2 2 2 0 FUSC-like inner membrane protein yccS DUF4014 PF13198.1 EGC32090.1 - 0.21 11.9 5.7 1.2 9.5 0.0 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF4014) Tetraspannin PF00335.15 EGC32090.1 - 0.83 8.8 10.1 2.1 7.5 3.6 2.5 1 1 1 2 2 2 0 Tetraspanin family SID-1_RNA_chan PF13965.1 EGC32090.1 - 1.3 7.1 16.5 0.052 11.7 0.6 2.9 1 1 0 2 2 2 0 dsRNA-gated channel SID-1 DUF4149 PF13664.1 EGC32090.1 - 1.9 8.6 15.0 16 5.6 0.7 3.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4149) DUF4131 PF13567.1 EGC32090.1 - 1.9 7.8 6.0 0.39 10.0 1.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4519 PF15012.1 EGC32090.1 - 4.9 7.1 5.4 8.8 6.3 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4519) Rho_GDI PF02115.12 EGC32091.1 - 1.4e-57 194.3 0.3 1.6e-57 194.1 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Proteasome PF00227.21 EGC32092.1 - 2.9e-52 176.7 0.0 4.3e-52 176.1 0.0 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC32092.1 - 5.5e-13 47.9 0.1 8.9e-13 47.2 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature RecA PF00154.16 EGC32092.1 - 0.024 13.6 0.0 0.038 13.0 0.0 1.2 1 0 0 1 1 1 0 recA bacterial DNA recombination protein DMPK_coil PF08826.5 EGC32092.1 - 0.18 11.7 1.6 1.2 9.0 0.0 2.5 2 0 0 2 2 2 0 DMPK coiled coil domain like HA2 PF04408.18 EGC32093.1 - 2.2e-30 104.6 0.1 2.2e-30 104.6 0.1 2.8 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGC32093.1 - 5.2e-30 103.5 0.9 1e-29 102.6 0.0 2.0 2 0 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold S1 PF00575.18 EGC32093.1 - 1.4e-08 34.6 3.3 4.9e-08 32.9 0.1 2.8 3 0 0 3 3 3 1 S1 RNA binding domain TRAM1 PF08390.6 EGC32094.1 - 0.047 13.1 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 TRAM1-like protein Robl_LC7 PF03259.12 EGC32095.1 - 0.002 17.6 0.0 0.0031 17.0 0.0 1.3 1 0 0 1 1 1 1 Roadblock/LC7 domain FNIP PF05725.7 EGC32096.1 - 4.5e-90 295.4 81.4 5.6e-13 48.6 0.4 9.7 3 2 6 11 11 11 11 FNIP Repeat DUF1769 PF08588.5 EGC32096.1 - 0.0085 16.0 10.5 8.7 6.3 0.0 6.6 5 3 2 7 7 7 3 Protein of unknown function (DUF1769) GET2 PF08690.5 EGC32097.1 - 4.1 6.5 5.7 0.57 9.3 0.0 2.1 2 0 0 2 2 2 0 GET complex subunit GET2 STAT_int PF02865.12 EGC32098.1 - 1.2 9.1 7.0 0.36 10.7 0.2 3.4 3 0 0 3 3 3 0 STAT protein, protein interaction domain SET PF00856.23 EGC32099.1 - 3e-13 50.3 17.7 3.2e-12 47.0 0.1 3.5 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EGC32099.1 - 3e-07 30.0 1.6 3e-07 30.0 1.1 2.7 2 1 2 4 4 4 1 TPR repeat TPR_2 PF07719.12 EGC32099.1 - 1.2e-05 24.8 0.5 0.046 13.6 0.2 3.3 4 0 0 4 4 4 2 Tetratricopeptide repeat CDC45 PF02724.9 EGC32099.1 - 0.0031 15.6 24.7 0.0053 14.8 5.8 2.1 2 0 0 2 2 2 2 CDC45-like protein TPR_1 PF00515.23 EGC32099.1 - 0.0074 15.8 5.5 0.01 15.4 0.3 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat DZR PF12773.2 EGC32099.1 - 0.47 10.3 19.2 0.23 11.2 1.0 3.1 2 1 1 3 3 3 0 Double zinc ribbon Mem_trans PF03547.13 EGC32099.1 - 2 6.6 7.0 11 4.2 0.0 2.2 2 0 0 2 2 2 0 Membrane transport protein Neur_chan_memb PF02932.11 EGC32099.1 - 3.2 7.5 13.2 2.6 7.8 1.2 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Raftlin PF15250.1 EGC32099.1 - 8.8 4.7 21.0 4 5.8 2.6 2.4 2 0 0 2 2 2 0 Raftlin FNIP PF05725.7 EGC32100.1 - 8.8e-104 339.2 39.9 1.7e-15 56.6 0.2 8.3 8 0 0 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 EGC32100.1 - 0.0029 17.2 3.1 0.056 13.1 0.1 3.7 1 1 0 2 2 2 1 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC32100.1 - 0.034 14.0 29.4 1.3 8.9 0.1 9.3 6 4 6 12 12 12 0 Protein of unknown function (DUF1769) PAT1 PF09770.4 EGC32102.1 - 4.3 5.4 38.4 11 4.0 26.6 1.7 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Maf PF02545.9 EGC32104.1 - 3.8e-45 153.4 0.0 4.6e-45 153.1 0.0 1.0 1 0 0 1 1 1 1 Maf-like protein GTP_EFTU PF00009.22 EGC32105.1 - 7.3e-28 97.2 0.0 1.1e-27 96.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGC32105.1 - 3.8e-14 52.2 0.0 6.9e-14 51.4 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_C PF00679.19 EGC32105.1 - 5.6e-11 42.1 0.0 1.1e-10 41.2 0.0 1.5 1 0 0 1 1 1 1 Elongation factor G C-terminus EFG_II PF14492.1 EGC32105.1 - 1.3e-07 31.3 0.0 3.1e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGC32105.1 - 1e-06 28.6 0.3 2.3e-06 27.5 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC32105.1 - 1.1e-05 24.7 0.1 2.2e-05 23.7 0.1 1.5 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC32105.1 - 0.00024 21.5 0.0 0.00057 20.3 0.0 1.7 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU_D2 PF03144.20 EGC32105.1 - 0.0064 16.5 0.0 0.029 14.4 0.0 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 RNA_pol PF00940.14 EGC32106.1 - 1.8e-162 540.4 0.0 3.2e-162 539.6 0.0 1.4 1 0 0 1 1 1 1 DNA-dependent RNA polymerase RPOL_N PF14700.1 EGC32106.1 - 1.3e-42 146.2 0.0 2.1e-42 145.5 0.0 1.3 1 0 0 1 1 1 1 DNA-directed RNA polymerase N-terminal FAM177 PF14774.1 EGC32107.1 - 5.1e-16 58.7 13.4 1e-15 57.7 9.3 1.5 1 1 0 1 1 1 1 FAM177 family DUF4475 PF14753.1 EGC32107.1 - 0.003 17.0 0.7 0.0042 16.6 0.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4475) FPN1 PF06963.7 EGC32107.1 - 0.07 11.5 0.2 0.097 11.0 0.2 1.1 1 0 0 1 1 1 0 Ferroportin1 (FPN1) Jacalin PF01419.12 EGC32107.1 - 0.082 12.7 3.7 0.16 11.8 2.6 1.5 1 0 0 1 1 1 0 Jacalin-like lectin domain CDC45 PF02724.9 EGC32107.1 - 0.12 10.3 7.8 0.16 9.9 5.4 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2126 PF09899.4 EGC32107.1 - 1.1 7.2 5.6 1.5 6.7 3.9 1.1 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) DUF4110 PF13422.1 EGC32107.1 - 3.8 7.4 12.8 12 5.8 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4110) PH_BEACH PF14844.1 EGC32107.1 - 5.3 6.9 7.5 0.6 9.9 2.2 1.7 2 0 0 2 2 2 0 PH domain associated with Beige/BEACH Ndc1_Nup PF09531.5 EGC32107.1 - 8.2 4.7 6.9 9.1 4.5 4.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF1900 PF08954.6 EGC32108.1 - 1.3e-58 196.3 0.0 7.3e-58 193.9 0.0 2.0 2 0 0 2 2 2 1 Domain of unknown function (DUF1900) DUF1899 PF08953.6 EGC32108.1 - 1.8e-32 110.7 0.3 3.9e-32 109.6 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) WD40 PF00400.27 EGC32108.1 - 3.3e-22 77.4 6.8 4.8e-07 29.4 0.1 3.7 3 0 0 3 3 3 3 WD domain, G-beta repeat CcdB PF01845.12 EGC32109.1 - 0.03 14.2 0.0 0.52 10.2 0.0 2.4 2 0 0 2 2 2 0 CcdB protein Asn_synthase PF00733.16 EGC32110.1 - 9.2e-54 182.6 0.0 1.2e-53 182.2 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC32110.1 - 2e-47 160.0 0.0 3.7e-47 159.1 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC32110.1 - 7.4e-37 126.2 0.0 1.3e-36 125.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGC32110.1 - 1.1e-05 24.3 0.0 0.14 10.8 0.0 2.5 1 1 1 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EGC32110.1 - 3.2e-05 23.2 0.0 7.9e-05 21.9 0.0 1.6 1 1 0 1 1 1 1 Aluminium induced protein Erf4 PF10256.4 EGC32111.1 - 1.3e-05 25.0 2.5 0.0001 22.1 1.8 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Trep_Strep PF09605.5 EGC32111.1 - 0.0029 17.3 2.5 0.0045 16.6 1.8 1.3 1 0 0 1 1 1 1 Hypothetical bacterial integral membrane protein (Trep_Strep) Sulfate_transp PF00916.15 EGC32111.1 - 0.005 15.8 0.7 0.0063 15.5 0.5 1.1 1 0 0 1 1 1 1 Sulfate transporter family DUF4181 PF13789.1 EGC32111.1 - 0.02 14.7 4.2 0.041 13.7 2.9 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4181) Wzy_C PF04932.10 EGC32111.1 - 0.048 13.4 2.5 0.076 12.7 1.8 1.3 1 0 0 1 1 1 0 O-Antigen ligase HDAC4_Gln PF12203.3 EGC32112.1 - 0.012 15.5 4.4 0.013 15.4 2.4 1.6 2 0 0 2 2 2 0 Glutamine rich N terminal domain of histone deacetylase 4 Syntaxin PF00804.20 EGC32112.1 - 0.17 12.0 4.9 0.32 11.1 3.1 1.6 1 1 0 1 1 1 0 Syntaxin DUF1273 PF06908.6 EGC32112.1 - 0.36 10.4 6.5 0.77 9.3 4.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1273) Pkinase PF00069.20 EGC32113.1 - 1.4e-73 247.3 0.0 1.7e-73 247.0 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32113.1 - 7.3e-37 126.8 0.0 9.6e-37 126.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EGC32113.1 - 4.8e-19 68.4 0.1 1.1e-18 67.3 0.1 1.6 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC32113.1 - 1.5e-10 41.3 1.5 1.5e-08 34.8 1.0 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain Pkinase_C PF00433.19 EGC32113.1 - 2e-08 34.5 0.1 4e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_3 PF14593.1 EGC32113.1 - 1.2e-06 28.3 0.0 2.9e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGC32113.1 - 0.00019 20.4 0.0 0.0019 17.1 0.0 2.0 1 1 1 2 2 2 1 Kinase-like PH_9 PF15410.1 EGC32113.1 - 0.024 14.7 0.7 0.16 12.1 0.0 2.5 2 2 0 2 2 2 0 Pleckstrin homology domain APH PF01636.18 EGC32113.1 - 0.064 12.9 0.0 0.13 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC32113.1 - 0.11 11.5 0.0 0.59 9.1 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L1 PF00687.16 EGC32114.1 - 1.5e-20 73.5 9.9 1.5e-20 73.5 6.9 2.3 1 1 1 2 2 2 1 Ribosomal protein L1p/L10e family Beta-lactamase2 PF13354.1 EGC32115.1 - 4.6e-22 78.4 0.0 4e-21 75.3 0.0 1.9 1 1 0 1 1 1 1 Beta-lactamase enzyme family ETRAMP PF09716.5 EGC32115.1 - 0.24 11.3 0.7 0.66 9.9 0.0 2.1 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DPBB_1 PF03330.13 EGC32116.1 - 3e-13 49.5 0.1 5.7e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EGC32116.1 - 7.9e-05 22.3 0.1 0.00013 21.6 0.0 1.4 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 EGC32116.1 - 0.0015 18.1 0.2 0.015 14.9 0.0 2.2 2 0 0 2 2 2 1 Barwin family Cerato-platanin PF07249.7 EGC32116.1 - 0.02 14.9 0.1 0.047 13.6 0.1 1.7 1 0 0 1 1 1 0 Cerato-platanin DPBB_1 PF03330.13 EGC32117.1 - 1.3e-09 37.9 0.0 2.6e-09 36.9 0.0 1.6 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EGC32117.1 - 0.00046 19.9 0.0 0.001 18.8 0.0 1.6 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 EGC32117.1 - 0.033 13.8 0.0 0.061 12.9 0.0 1.4 1 0 0 1 1 1 0 Barwin family ATP-synt_G PF04718.10 EGC32119.1 - 3.9e-05 24.2 0.0 4.4e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial ATP synthase g subunit SSP160 PF06933.6 EGC32120.1 - 0.04 11.9 8.8 0.047 11.6 6.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGC32120.1 - 0.066 12.9 9.2 0.029 14.1 4.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC32120.1 - 0.08 12.7 12.7 0.11 12.3 8.8 1.1 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF869 PF05911.6 EGC32120.1 - 2.1 6.4 17.9 2.3 6.3 12.4 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) Myb_DNA-binding PF00249.26 EGC32122.1 - 1.2e-28 98.8 7.2 5.5e-14 51.9 0.1 2.4 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC32122.1 - 8.7e-24 83.3 8.1 1.1e-15 57.4 1.6 2.8 1 1 1 2 2 2 2 Myb-like DNA-binding domain PHD PF00628.24 EGC32122.1 - 0.00029 20.4 17.3 0.00068 19.2 12.0 1.7 1 0 0 1 1 1 1 PHD-finger Rap1_C PF11626.3 EGC32122.1 - 0.002 17.9 2.0 0.12 12.2 0.2 2.4 1 1 1 2 2 2 1 TRF2-interacting telomeric protein/Rap1 - C terminal domain Spc7_N PF15402.1 EGC32122.1 - 0.0046 15.0 12.4 0.0056 14.7 8.6 1.0 1 0 0 1 1 1 1 N-terminus of kinetochore NMS complex subunit Spc7 Nucleo_P87 PF07267.6 EGC32122.1 - 0.018 13.7 5.0 0.022 13.5 3.4 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 DUF959 PF06121.9 EGC32122.1 - 0.068 12.8 10.9 0.099 12.2 7.6 1.2 1 0 0 1 1 1 0 Domain of Unknown Function (DUF959) DZR PF12773.2 EGC32122.1 - 0.14 12.0 11.4 0.4 10.5 7.9 1.8 1 0 0 1 1 1 0 Double zinc ribbon Prok-RING_1 PF14446.1 EGC32122.1 - 0.21 11.3 15.8 0.8 9.4 11.0 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 1 CENP-B_dimeris PF09026.5 EGC32122.1 - 0.39 10.9 7.0 0.73 10.1 4.8 1.4 1 0 0 1 1 1 0 Centromere protein B dimerisation domain zf-ribbon_3 PF13248.1 EGC32122.1 - 5.2 6.3 10.0 1.3 8.2 3.6 2.3 2 0 0 2 2 2 0 zinc-ribbon domain Sporozoite_P67 PF05642.6 EGC32122.1 - 9.9 3.8 18.6 13 3.5 12.9 1.0 1 0 0 1 1 1 0 Sporozoite P67 surface antigen TIMELESS PF04821.9 EGC32123.1 - 1.3e-29 103.3 10.2 1.3e-29 103.3 7.1 8.7 7 3 3 11 11 11 1 Timeless protein TIMELESS_C PF05029.8 EGC32123.1 - 1e-11 44.5 1.3 1e-11 44.5 0.9 7.9 4 1 5 10 10 10 2 Timeless protein C terminal region DDRGK PF09756.4 EGC32125.1 - 0.61 9.4 10.7 1 8.7 7.4 1.3 1 0 0 1 1 1 0 DDRGK domain DUF1180 PF06679.7 EGC32126.1 - 0.71 9.7 2.5 13 5.5 2.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) Bromodomain PF00439.20 EGC32127.1 - 3.9e-26 90.7 1.5 1.6e-25 88.8 1.0 2.2 1 0 0 1 1 1 1 Bromodomain BTB PF00651.26 EGC32127.1 - 1e-09 38.3 7.3 1.7e-09 37.6 0.8 3.4 3 0 0 3 3 3 1 BTB/POZ domain CDC27 PF09507.5 EGC32127.1 - 3 6.9 33.9 3.7 6.6 7.0 2.3 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 Anophelin PF10731.4 EGC32128.1 - 0.69 10.0 4.7 1.6 8.9 3.2 1.6 1 0 0 1 1 1 0 Thrombin inhibitor from mosquito TBX PF12598.3 EGC32128.1 - 4.3 7.7 6.7 2.4 8.5 0.4 2.1 2 0 0 2 2 2 0 T-box transcription factor Nse4-Nse3_bdg PF15412.1 EGC32129.1 - 0.036 13.9 0.3 0.29 10.9 0.0 2.3 2 0 0 2 2 2 0 Binding domain of Nse4/EID3 to Nse3-MAGE Phage_int_SAM_4 PF13495.1 EGC32129.1 - 0.49 10.7 0.1 0.49 10.7 0.1 3.3 3 2 1 4 4 4 0 Phage integrase, N-terminal SAM-like domain Gla PF00594.15 EGC32130.1 - 0.05 13.3 0.0 0.13 11.9 0.0 1.7 1 0 0 1 1 1 0 Vitamin K-dependent carboxylation/gamma-carboxyglutamic (GLA) domain YL1_C PF08265.6 EGC32131.1 - 1.1e-14 53.7 0.7 3.8e-14 51.9 0.0 2.1 2 0 0 2 2 2 1 YL1 nuclear protein C-terminal domain YL1 PF05764.8 EGC32131.1 - 3.1e-14 53.1 59.7 1.9e-10 40.7 10.1 4.0 3 1 1 4 4 4 2 YL1 nuclear protein Peptidase_S76 PF13611.1 EGC32131.1 - 0.021 14.9 1.7 0.08 13.0 1.2 2.0 1 0 0 1 1 1 0 Serine peptidase of plant viral polyprotein, P1 Arf PF00025.16 EGC32132.1 - 4.2e-61 205.1 0.2 4.6e-61 205.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC32132.1 - 6.7e-10 38.4 0.0 8.2e-10 38.1 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC32132.1 - 3.2e-09 36.3 0.0 3.9e-09 36.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC32132.1 - 3.6e-09 36.0 0.1 4.2e-09 35.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGC32132.1 - 9.4e-09 34.4 1.6 1.9e-07 30.1 0.5 2.1 1 1 1 2 2 2 1 G-protein alpha subunit Miro PF08477.8 EGC32132.1 - 1.6e-08 35.0 0.0 2.2e-08 34.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC32132.1 - 0.00019 21.3 0.0 0.00039 20.3 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase PolyA_pol PF01743.15 EGC32133.1 - 5.3e-25 88.0 0.9 1.2e-24 86.9 0.1 2.0 2 0 0 2 2 2 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGC32133.1 - 0.00085 18.8 0.0 0.0019 17.7 0.0 1.6 1 0 0 1 1 1 1 Probable RNA and SrmB- binding site of polymerase A tRNA_NucTran2_2 PF13735.1 EGC32133.1 - 0.021 14.6 0.1 0.073 12.8 0.1 1.9 2 0 0 2 2 2 0 tRNA nucleotidyltransferase domain 2 putative Rac1 PF09632.5 EGC32133.1 - 0.086 11.8 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 Rac1-binding domain G-patch PF01585.18 EGC32134.1 - 1.8e-08 34.0 1.2 5.6e-08 32.4 0.8 1.9 1 0 0 1 1 1 1 G-patch domain ACR_tran PF00873.14 EGC32134.1 - 5.4 4.2 5.4 8.2 3.6 3.8 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Vps52 PF04129.7 EGC32135.1 - 1.7e-68 231.4 38.3 1.1e-63 215.5 19.2 2.6 2 1 1 3 3 3 2 Vps52 / Sac2 family T-box PF00907.17 EGC32136.1 - 0.081 12.4 0.1 0.11 12.0 0.1 1.2 1 0 0 1 1 1 0 T-box UQ_con PF00179.21 EGC32137.1 - 8.9e-22 77.0 0.0 1.1e-21 76.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Sec6 PF06046.8 EGC32138.1 - 3.1e-134 448.1 12.1 3.1e-134 448.1 8.4 2.0 2 0 0 2 2 2 2 Exocyst complex component Sec6 Sec20 PF03908.8 EGC32138.1 - 0.0012 18.5 7.0 0.0034 17.0 0.2 4.0 1 1 3 4 4 4 1 Sec20 Flagellin_N PF00669.15 EGC32138.1 - 0.49 10.1 3.8 0.42 10.3 0.1 2.6 3 0 0 3 3 3 0 Bacterial flagellin N-terminal helical region RhoGAP PF00620.22 EGC32139.1 - 5.2e-21 74.8 0.1 1.5e-20 73.3 0.1 1.8 1 0 0 1 1 1 1 RhoGAP domain Mem_trans PF03547.13 EGC32139.1 - 0.0023 16.2 0.7 0.0035 15.6 0.5 1.3 1 0 0 1 1 1 1 Membrane transport protein Serinc PF03348.10 EGC32139.1 - 0.0076 15.0 6.6 0.017 13.8 4.6 1.7 1 1 0 1 1 1 1 Serine incorporator (Serinc) Neur_chan_memb PF02932.11 EGC32139.1 - 0.091 12.6 3.0 0.18 11.6 2.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF3328 PF11807.3 EGC32139.1 - 0.12 12.0 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Zip PF02535.17 EGC32139.1 - 0.15 11.0 4.0 0.3 10.0 2.8 1.5 1 0 0 1 1 1 0 ZIP Zinc transporter Otopetrin PF03189.8 EGC32139.1 - 0.32 9.9 5.2 0.34 9.8 3.5 1.3 1 1 0 1 1 1 0 Otopetrin DUF106 PF01956.11 EGC32139.1 - 0.51 9.8 2.9 1.1 8.8 2.0 1.6 1 0 0 1 1 1 0 Integral membrane protein DUF106 GAGA_bind PF06217.7 EGC32139.1 - 1.1 9.2 12.3 4.1 7.2 5.5 3.0 2 1 1 3 3 3 0 GAGA binding protein-like family Peptidase_C48 PF02902.14 EGC32140.1 - 2.6e-23 82.7 0.9 2.6e-23 82.7 0.6 2.7 3 0 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain Ribosomal_L23eN PF03939.8 EGC32141.1 - 1.3e-17 63.5 11.4 1.3e-17 63.5 7.9 2.4 3 0 0 3 3 3 1 Ribosomal protein L23, N-terminal domain Ribosomal_L23 PF00276.15 EGC32141.1 - 4.3e-16 58.6 1.1 1.2e-15 57.2 0.8 1.8 1 0 0 1 1 1 1 Ribosomal protein L23 SEP PF08059.8 EGC32142.1 - 3.7e-25 88.0 0.0 1.2e-24 86.4 0.0 1.9 2 0 0 2 2 2 1 SEP domain UBA_4 PF14555.1 EGC32142.1 - 1.7e-16 59.4 0.5 5.1e-16 57.9 0.4 1.9 1 0 0 1 1 1 1 UBA-like domain UBX PF00789.15 EGC32142.1 - 2.4e-14 53.1 0.0 4.7e-14 52.1 0.0 1.5 1 0 0 1 1 1 1 UBX domain FtsH_ext PF06480.10 EGC32142.1 - 6.3 7.0 11.5 2.4 8.3 1.9 2.6 2 0 0 2 2 2 0 FtsH Extracellular Coiled PF05710.7 EGC32143.1 - 9.2e-20 70.9 18.4 1e-19 70.7 12.8 1.0 1 0 0 1 1 1 1 Coiled coil adh_short PF00106.20 EGC32145.1 - 1.2e-18 67.6 0.0 1.5e-18 67.2 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC32145.1 - 4e-12 46.4 0.0 5.3e-12 46.0 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC32145.1 - 9.3e-06 25.4 0.0 1.6e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGC32145.1 - 0.00061 19.5 0.0 0.0012 18.5 0.0 1.4 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGC32145.1 - 0.008 16.1 0.1 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EGC32145.1 - 0.094 12.3 0.0 0.14 11.7 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ras PF00071.17 EGC32148.1 - 1.5e-28 99.1 0.4 2.2e-28 98.6 0.2 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32148.1 - 3.4e-13 50.1 0.3 6.8e-13 49.1 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC32148.1 - 0.00069 18.9 0.0 0.00085 18.6 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC32148.1 - 0.015 15.2 0.0 0.024 14.6 0.0 1.6 1 1 0 1 1 1 0 50S ribosome-binding GTPase Auxin_BP PF02041.11 EGC32148.1 - 0.042 13.2 0.0 0.048 13.1 0.0 1.2 1 0 0 1 1 1 0 Auxin binding protein Ras PF00071.17 EGC32149.1 - 2.2e-36 124.6 1.2 3e-36 124.2 0.8 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32149.1 - 2.4e-14 53.8 0.0 4.3e-14 53.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC32149.1 - 0.00025 20.3 1.0 0.0005 19.3 0.7 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family AAA_14 PF13173.1 EGC32149.1 - 1.3 8.9 7.1 0.065 13.1 0.3 2.1 1 1 1 2 2 2 0 AAA domain Bromodomain PF00439.20 EGC32151.1 - 6.9e-19 67.5 2.3 6.9e-19 67.5 1.6 2.8 3 0 0 3 3 3 1 Bromodomain MFS_1_like PF12832.2 EGC32152.1 - 9e-09 35.0 1.3 9e-09 35.0 0.9 2.8 2 0 0 2 2 2 1 MFS_1 like family DUF3730 PF12530.3 EGC32154.1 - 1.7e-51 175.3 7.2 2.1e-51 175.1 3.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3730) DUF3236 PF11576.3 EGC32154.1 - 0.018 14.4 0.5 1.4 8.3 0.0 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3236) Myotub-related PF06602.9 EGC32155.1 - 2.5e-117 391.6 0.4 3.6e-65 220.0 1.5 2.8 2 1 1 3 3 3 2 Myotubularin-like phosphatase domain Y_phosphatase PF00102.22 EGC32155.1 - 1.8e-05 24.1 0.3 9.2e-05 21.8 0.0 2.3 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC32155.1 - 0.012 15.8 0.0 0.04 14.1 0.0 1.8 1 0 0 1 1 1 0 Tyrosine phosphatase family GRAM PF02893.15 EGC32155.1 - 0.013 15.0 0.1 0.043 13.3 0.0 1.9 1 0 0 1 1 1 0 GRAM domain DSPc PF00782.15 EGC32155.1 - 0.041 13.4 0.1 0.041 13.4 0.0 3.2 2 1 1 3 3 3 0 Dual specificity phosphatase, catalytic domain PI3K_rbd PF00794.13 EGC32155.1 - 0.064 13.1 8.9 0.22 11.4 0.1 3.7 4 0 0 4 4 4 0 PI3-kinase family, ras-binding domain DEAD PF00270.24 EGC32156.1 - 5.5e-34 117.0 0.0 1.3e-33 115.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC32156.1 - 4.3e-23 80.9 2.1 1.6e-21 75.9 0.1 2.9 3 0 0 3 3 3 2 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGC32156.1 - 0.047 13.6 1.7 0.51 10.2 0.0 3.3 3 0 0 3 3 3 0 Helicase C-terminal domain DEAD PF00270.24 EGC32157.1 - 1e-49 168.2 0.1 3.4e-49 166.5 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC32157.1 - 3.9e-20 71.5 0.1 1.8e-19 69.3 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DBP10CT PF08147.7 EGC32157.1 - 7.5e-16 57.6 7.4 7.5e-16 57.6 5.1 3.9 4 0 0 4 4 4 1 DBP10CT (NUC160) domain p450 PF00067.17 EGC32158.1 - 1.3e-18 66.8 0.0 1.4e-18 66.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 zf-TRAF PF02176.13 EGC32159.1 - 8.9e-14 51.6 21.7 1.1e-08 35.3 4.1 4.5 1 1 3 4 4 4 2 TRAF-type zinc finger MATH PF00917.21 EGC32159.1 - 1.6e-06 28.3 1.9 5.2e-06 26.6 0.1 2.4 2 1 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.1 EGC32159.1 - 0.00047 20.1 10.8 0.00047 20.1 7.5 3.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC32159.1 - 0.0011 18.6 6.1 0.0011 18.6 4.3 3.3 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-U11-48K PF05253.7 EGC32159.1 - 0.73 9.6 5.2 31 4.4 0.0 4.1 4 0 0 4 4 4 0 U11-48K-like CHHC zinc finger Phage_Mu_Gam PF07352.7 EGC32160.1 - 0.0085 15.6 1.1 0.0085 15.6 0.7 1.1 1 0 0 1 1 1 1 Bacteriophage Mu Gam like protein V_ATPase_I PF01496.14 EGC32160.1 - 0.027 12.3 1.5 0.027 12.3 1.0 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Mdv1 PF11542.3 EGC32160.1 - 0.043 13.7 0.0 0.051 13.4 0.0 1.2 1 0 0 1 1 1 0 Mitochondrial division protein 1 FlxA PF14282.1 EGC32160.1 - 0.056 13.4 2.7 0.059 13.3 1.9 1.1 1 0 0 1 1 1 0 FlxA-like protein Spc42p PF11544.3 EGC32160.1 - 0.063 13.2 0.6 0.075 12.9 0.4 1.1 1 0 0 1 1 1 0 Spindle pole body component Spc42p SlyX PF04102.7 EGC32160.1 - 0.15 12.4 0.7 0.16 12.3 0.5 1.0 1 0 0 1 1 1 0 SlyX OTU PF02338.14 EGC32161.1 - 1.1e-13 51.8 0.1 1.4e-13 51.4 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease Chromo PF00385.19 EGC32162.1 - 1.7e-07 30.7 0.4 2.4e-07 30.2 0.3 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain SbcD_C PF12320.3 EGC32163.1 - 0.0017 18.3 1.0 0.0017 18.3 0.7 5.7 4 2 0 5 5 5 2 Type 5 capsule protein repressor C-terminal domain Phasin_2 PF09361.5 EGC32163.1 - 0.006 16.5 8.2 0.006 16.5 5.7 3.3 5 0 0 5 5 5 1 Phasin protein Spc7 PF08317.6 EGC32163.1 - 0.88 8.1 55.2 0.051 12.2 4.8 3.3 2 1 1 3 3 3 0 Spc7 kinetochore protein ketoacyl-synt PF00109.21 EGC32164.1 - 1.4e-62 211.4 0.0 2e-62 210.9 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32164.1 - 2.4e-46 158.5 0.0 3.7e-46 157.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC32164.1 - 3.6e-34 117.1 0.0 7e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC32164.1 - 1.4e-26 93.2 0.0 2.8e-26 92.2 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC32164.1 - 5.8e-22 78.2 0.0 8.4e-22 77.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC32164.1 - 1.1e-13 51.3 0.0 2.2e-13 50.4 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_12 PF08242.7 EGC32164.1 - 2.8e-11 43.7 2.8 2.9e-10 40.5 0.0 3.9 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 EGC32164.1 - 6.7e-10 38.6 0.0 2.1e-09 37.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC32164.1 - 2.5e-06 28.3 0.0 6.8e-06 26.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGC32164.1 - 0.0056 16.9 0.0 0.015 15.5 0.0 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC32164.1 - 0.061 12.3 0.0 0.14 11.1 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 EGC32164.1 - 0.17 12.4 0.0 0.61 10.6 0.0 2.0 1 0 0 1 1 1 0 Methyltransferase domain PTPLA PF04387.9 EGC32165.1 - 3.1e-45 153.5 9.0 3.6e-45 153.3 6.2 1.0 1 0 0 1 1 1 1 Protein tyrosine phosphatase-like protein, PTPLA UPF0020 PF01170.13 EGC32166.1 - 1.9e-15 56.9 1.8 1.7e-13 50.5 0.0 2.8 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_26 PF13659.1 EGC32166.1 - 5.8e-05 23.1 0.0 0.00011 22.2 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC32166.1 - 0.065 13.7 4.8 0.14 12.6 0.1 2.9 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32166.1 - 0.14 11.7 14.1 0.072 12.6 5.3 3.1 3 1 0 3 3 3 0 Methyltransferase domain MitMem_reg PF13012.1 EGC32167.1 - 1.6e-27 95.8 1.4 2.7e-27 95.1 1.0 1.4 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGC32167.1 - 2.8e-22 78.6 0.0 5.4e-22 77.6 0.0 1.4 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Pox_Ag35 PF03286.9 EGC32168.1 - 0.002 17.7 21.4 0.003 17.1 14.8 1.3 1 0 0 1 1 1 1 Pox virus Ag35 surface protein Hid1 PF12722.2 EGC32168.1 - 0.029 12.0 18.4 0.031 12.0 12.7 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Daxx PF03344.10 EGC32168.1 - 0.1 11.0 33.5 0.12 10.8 23.2 1.1 1 0 0 1 1 1 0 Daxx Family DUF1510 PF07423.6 EGC32168.1 - 0.16 11.3 33.9 0.22 10.8 23.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF3381 PF11861.3 EGC32168.1 - 0.5 9.8 31.2 1 8.8 21.6 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF3381) CDC45 PF02724.9 EGC32168.1 - 0.54 8.2 19.6 0.67 7.9 13.6 1.2 1 0 0 1 1 1 0 CDC45-like protein BUD22 PF09073.5 EGC32168.1 - 0.8 8.7 30.8 1.1 8.2 21.4 1.1 1 0 0 1 1 1 0 BUD22 CENP-T PF15511.1 EGC32168.1 - 0.94 8.6 12.1 1.2 8.3 8.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T RNA_pol_3_Rpc31 PF11705.3 EGC32168.1 - 2.6 7.9 29.4 4.1 7.2 20.4 1.4 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 DUF2201_N PF13203.1 EGC32168.1 - 7.2 5.6 11.4 9.1 5.3 7.9 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF2967 PF11179.3 EGC32168.1 - 7.7 5.9 8.7 10 5.5 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2967) Arf PF00025.16 EGC32169.1 - 3.5e-64 215.2 0.1 4.1e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC32169.1 - 1.6e-13 50.3 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC32169.1 - 4.8e-11 42.1 0.0 5.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC32169.1 - 2.9e-10 40.6 0.0 3.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EGC32169.1 - 2.9e-09 36.1 2.0 9.8e-07 27.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGC32169.1 - 2.9e-08 33.1 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC32169.1 - 1.1e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGC32169.1 - 0.012 15.9 0.1 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EGC32169.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EGC32169.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EGC32169.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Flu_PA PF00603.12 EGC32170.1 - 0.077 11.0 0.2 0.091 10.7 0.1 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA zf-CCHC PF00098.18 EGC32171.1 - 0.00014 21.5 1.5 0.00033 20.4 1.0 1.7 1 0 0 1 1 1 1 Zinc knuckle RRM_1 PF00076.17 EGC32172.1 - 2.4e-29 100.7 0.0 3e-14 52.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC32172.1 - 7.8e-24 83.2 0.7 5.2e-11 42.2 0.1 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC32172.1 - 3.4e-23 81.3 0.0 1.1e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EGC32172.1 - 5.2e-15 54.8 0.1 5.2e-15 54.8 0.1 2.0 2 0 0 2 2 2 1 Surp module CTK3 PF12243.3 EGC32172.1 - 3e-07 30.1 0.3 5.3e-07 29.3 0.2 1.3 1 0 0 1 1 1 1 CTD kinase subunit gamma CTK3 CTD_bind PF04818.8 EGC32172.1 - 1.2e-06 28.6 0.0 2.5e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase II-binding domain. RRM_3 PF08777.6 EGC32172.1 - 0.0041 16.9 0.0 0.54 10.1 0.0 2.5 2 0 0 2 2 2 1 RNA binding motif Nup35_RRM_2 PF14605.1 EGC32172.1 - 0.02 14.6 0.0 2.7 7.8 0.0 2.4 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif 4HB_MCP_1 PF12729.2 EGC32172.1 - 0.02 14.2 1.2 0.036 13.4 0.8 1.3 1 0 0 1 1 1 0 Four helix bundle sensory module for signal transduction Xan_ur_permease PF00860.15 EGC32173.1 - 5.5e-70 235.8 42.5 2.6e-69 233.5 29.4 1.9 1 1 0 1 1 1 1 Permease family PIG-U PF06728.8 EGC32175.1 - 0.0051 15.7 0.3 0.0069 15.2 0.1 1.2 1 1 0 1 1 1 1 GPI transamidase subunit PIG-U DUF4083 PF13314.1 EGC32175.1 - 0.026 14.3 0.2 0.35 10.7 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Tetraspannin PF00335.15 EGC32175.1 - 0.036 13.3 5.7 0.14 11.4 3.9 2.0 1 1 0 1 1 1 0 Tetraspanin family DUF4396 PF14342.1 EGC32175.1 - 0.91 9.6 5.8 2.1 8.4 3.1 2.2 2 1 1 3 3 3 0 Domain of unknown function (DUF4396) DUF2108 PF09881.4 EGC32175.1 - 1.9 8.3 5.0 0.93 9.3 0.5 2.5 1 1 2 3 3 3 0 Predicted membrane protein (DUF2108) DUF805 PF05656.9 EGC32175.1 - 2.1 8.2 6.8 1.8 8.3 3.8 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF805) DUF454 PF04304.8 EGC32175.1 - 7.8 6.6 11.3 0.4 10.7 2.5 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF454) p450 PF00067.17 EGC32176.1 - 3.9e-44 150.9 0.0 4.4e-44 150.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Myb_DNA-binding PF00249.26 EGC32177.1 - 4.6e-12 45.7 0.0 1.7e-11 43.9 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC32177.1 - 0.00071 19.6 0.1 0.0035 17.4 0.1 2.3 1 0 0 1 1 1 1 Myb-like DNA-binding domain V_ATPase_I PF01496.14 EGC32177.1 - 0.05 11.4 0.0 0.05 11.4 0.0 2.1 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family Pkinase PF00069.20 EGC32178.1 - 9.5e-69 231.4 0.9 1.7e-68 230.6 0.0 1.9 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32178.1 - 2.2e-33 115.4 0.0 4.5e-33 114.4 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC32178.1 - 1.9e-07 30.3 0.0 5.6e-07 28.8 0.0 1.9 1 1 0 1 1 1 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGC32178.1 - 4.9e-05 22.7 0.1 0.00015 21.1 0.1 1.8 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kdo PF06293.9 EGC32178.1 - 8.5e-05 21.7 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC32178.1 - 0.0002 20.7 0.2 0.0002 20.7 0.1 2.5 3 0 0 3 3 3 1 RIO1 family Med7 PF05983.6 EGC32179.1 - 0.091 12.5 0.2 0.1 12.4 0.1 1.0 1 0 0 1 1 1 0 MED7 protein HTH_Tnp_4 PF13613.1 EGC32180.1 - 0.00015 21.1 0.1 0.00032 20.1 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease DltD_C PF04914.7 EGC32180.1 - 0.031 14.1 0.2 0.06 13.2 0.2 1.6 1 0 0 1 1 1 0 DltD C-terminal region SAM_2 PF07647.12 EGC32181.1 - 1.3e-09 37.7 0.6 1.1e-05 25.1 0.1 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC32181.1 - 2.3e-09 37.2 0.2 4.3e-05 23.6 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EGC32181.1 - 3.6e-05 23.4 1.3 0.0098 15.6 0.1 2.7 3 0 0 3 3 3 2 Sterile alpha motif (SAM)/Pointed domain TA0956 PF11513.3 EGC32181.1 - 0.072 13.1 1.5 0.33 11.0 0.3 2.3 2 0 0 2 2 2 0 Thermoplasma acidophilum protein TA0956 SAM_2 PF07647.12 EGC32182.1 - 0.00081 19.1 0.3 0.0082 15.9 0.0 2.2 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC32182.1 - 0.013 15.6 0.1 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 SAM domain (Sterile alpha motif) NAD_binding_4 PF07993.7 EGC32183.1 - 2.9e-32 111.5 0.0 4.4e-32 110.9 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGC32183.1 - 0.0008 18.9 0.0 0.0014 18.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family ketoacyl-synt PF00109.21 EGC32184.1 - 1.1e-59 201.9 0.0 1.6e-59 201.4 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32184.1 - 3.1e-53 181.1 0.0 5.3e-53 180.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC32184.1 - 6.9e-29 100.1 0.0 1.3e-28 99.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC32184.1 - 2.6e-23 82.3 0.0 1.5e-22 79.9 0.0 2.5 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.5 EGC32184.1 - 6.9e-23 81.2 0.0 1.2e-22 80.5 0.0 1.3 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC32184.1 - 1.2e-19 70.6 0.0 1.8e-19 70.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC32184.1 - 5.6e-15 55.6 0.0 3.7e-14 52.9 0.0 2.3 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC32184.1 - 3.8e-10 39.7 0.0 3.4e-09 36.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC32184.1 - 5.9e-09 36.8 0.0 1.4e-08 35.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EGC32184.1 - 1.3e-07 31.9 0.0 5.1e-07 30.1 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32184.1 - 0.00062 18.8 0.1 0.0015 17.5 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 EGC32184.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 Alcohol dehydrogenase GroES-like domain HhH-GPD PF00730.20 EGC32185.1 - 4e-25 88.1 0.0 6.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein HHH PF00633.18 EGC32185.1 - 1.9e-07 30.3 0.0 4.6e-07 29.1 0.0 1.7 1 0 0 1 1 1 1 Helix-hairpin-helix motif EndIII_4Fe-2S PF10576.4 EGC32185.1 - 0.049 13.8 5.0 0.082 13.1 3.4 1.4 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III NAD_binding_4 PF07993.7 EGC32186.1 - 1.7e-45 154.9 0.0 3e-45 154.1 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGC32186.1 - 1.1e-05 24.9 0.0 2.4e-05 23.8 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGC32187.1 - 3.6e-22 78.9 0.0 6.1e-22 78.1 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC32187.1 - 8.6e-13 48.5 0.0 1.2e-12 48.0 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC32187.1 - 2.7e-06 28.3 0.0 5.1e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Acyl_transf_1 PF00698.16 EGC32189.1 - 5.4e-52 177.1 0.0 8.6e-52 176.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Methyltransf_12 PF08242.7 EGC32189.1 - 5.5e-24 84.5 0.0 2.8e-23 82.2 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 EGC32189.1 - 1.1e-19 70.7 0.0 1.6e-19 70.1 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EGC32189.1 - 5.3e-10 39.2 0.0 1.5e-09 37.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC32189.1 - 2.6e-07 31.0 0.0 6.2e-07 29.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32189.1 - 4.1e-07 29.7 0.3 2.1e-06 27.4 0.2 2.4 1 0 0 1 1 1 1 Methyltransferase domain Ketoacyl-synt_C PF02801.17 EGC32189.1 - 1.3e-06 28.1 0.0 2.5e-06 27.3 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain HTH_23 PF13384.1 EGC32189.1 - 8.7e-05 22.0 0.1 0.0002 20.9 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGC32189.1 - 0.0011 18.9 0.2 0.0023 17.8 0.2 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EGC32189.1 - 0.012 15.8 0.0 0.024 14.7 0.0 1.5 1 0 0 1 1 1 0 Winged helix-turn helix HTH_38 PF13936.1 EGC32189.1 - 0.014 14.9 0.1 0.032 13.7 0.1 1.7 1 0 0 1 1 1 0 Helix-turn-helix domain Methyltransf_18 PF12847.2 EGC32189.1 - 0.048 14.2 0.0 0.13 12.8 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain ketoacyl-synt PF00109.21 EGC32190.1 - 5.4e-36 124.3 5.3 2.9e-15 56.4 1.5 4.1 1 1 2 3 3 3 3 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC32190.1 - 6e-20 71.2 0.0 1.3e-19 70.1 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGC32190.1 - 0.00013 21.0 0.5 0.0002 20.4 0.3 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Pkinase PF00069.20 EGC32191.1 - 1.3e-56 191.6 0.0 3.5e-56 190.2 0.0 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32191.1 - 1.5e-30 106.1 0.0 2.8e-30 105.2 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HhH-GPD PF00730.20 EGC32191.1 - 2.9e-24 85.4 0.0 6.2e-24 84.3 0.0 1.6 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein SAM_1 PF00536.25 EGC32191.1 - 1.1e-10 41.5 0.7 1.4e-09 37.9 0.0 2.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC32191.1 - 1.5e-09 37.5 0.0 6.2e-09 35.5 0.0 2.1 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) HHH PF00633.18 EGC32191.1 - 8.7e-07 28.3 0.0 1.9e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix motif APH PF01636.18 EGC32191.1 - 6.6e-05 22.7 0.0 0.0011 18.7 0.3 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC32191.1 - 0.001 18.4 0.0 0.0027 17.0 0.0 1.6 1 0 0 1 1 1 1 RIO1 family HHH_8 PF14716.1 EGC32191.1 - 0.086 13.0 0.1 4 7.7 0.0 2.5 2 0 0 2 2 2 0 Helix-hairpin-helix domain EndIII_4Fe-2S PF10576.4 EGC32191.1 - 0.15 12.3 5.0 0.3 11.3 3.4 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III Pkinase PF00069.20 EGC32192.1 - 5.3e-57 192.9 0.1 1.3e-56 191.6 0.0 1.7 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32192.1 - 4.2e-31 107.9 0.0 6.8e-31 107.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase SAM_1 PF00536.25 EGC32192.1 - 1.3e-10 41.2 0.0 3.6e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC32192.1 - 1.7e-08 34.1 0.3 5.4e-08 32.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) RIO1 PF01163.17 EGC32192.1 - 0.011 15.1 0.2 0.023 14.0 0.1 1.7 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGC32192.1 - 0.013 15.1 0.0 0.069 12.8 0.2 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGC32192.1 - 0.024 13.6 0.0 0.59 9.0 0.0 2.4 1 1 1 2 2 2 0 Kinase-like Pkinase PF00069.20 EGC32193.1 - 8.2e-59 198.8 0.1 1.4e-58 198.1 0.1 1.3 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32193.1 - 6.6e-30 104.0 0.0 8.4e-30 103.7 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC32193.1 - 7.3e-05 22.6 0.1 0.00029 20.6 0.2 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC32193.1 - 8.2e-05 22.0 0.2 0.00012 21.5 0.1 1.3 1 1 0 1 1 1 1 RIO1 family Kinase-like PF14531.1 EGC32193.1 - 0.023 13.6 0.1 0.16 10.8 0.0 2.3 1 1 0 2 2 2 0 Kinase-like Kdo PF06293.9 EGC32193.1 - 0.068 12.2 0.0 0.11 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 EGC32195.1 - 5.4e-11 42.1 9.5 8.7e-11 41.4 6.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC32195.1 - 8.3e-09 34.9 7.7 1.3e-08 34.4 5.3 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC32195.1 - 1.9e-08 34.3 5.3 3.8e-08 33.3 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC32195.1 - 2.5e-07 30.2 12.2 4.4e-07 29.4 8.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32195.1 - 1.3e-06 28.2 10.6 2.2e-06 27.5 7.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32195.1 - 3.7e-05 23.3 10.0 6.2e-05 22.6 6.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain IBR PF01485.16 EGC32195.1 - 0.00082 19.2 8.0 0.0023 17.7 5.5 1.8 1 0 0 1 1 1 1 IBR domain zf-RING_4 PF14570.1 EGC32195.1 - 0.0029 17.1 10.5 0.0058 16.1 7.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC32195.1 - 0.0086 15.7 2.7 0.045 13.4 1.9 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC32195.1 - 0.0087 15.9 11.0 0.024 14.5 6.6 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC32195.1 - 0.017 14.6 4.9 0.034 13.6 3.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC32195.1 - 0.019 14.7 4.7 0.04 13.7 3.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC32195.1 - 0.083 12.7 7.3 0.16 11.8 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MIZ PF02891.15 EGC32195.1 - 0.14 11.6 7.8 0.29 10.6 5.4 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.1 EGC32195.1 - 0.17 11.6 2.7 0.36 10.6 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger Tmpp129 PF10272.4 EGC32195.1 - 6.1 5.4 20.2 6.6e+02 -1.3 13.5 3.1 1 1 0 1 1 1 0 Putative transmembrane protein precursor Neur_chan_memb PF02932.11 EGC32197.1 - 0.79 9.5 8.4 1.6 8.5 5.8 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Erf4 PF10256.4 EGC32198.1 - 0.0012 18.7 8.6 0.0042 16.9 5.8 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF4131 PF13567.1 EGC32198.1 - 0.059 12.7 0.6 0.089 12.1 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) FA_desaturase PF00487.19 EGC32198.1 - 0.13 11.6 0.1 0.18 11.1 0.1 1.2 1 0 0 1 1 1 0 Fatty acid desaturase FUSC_2 PF13515.1 EGC32198.1 - 0.9 9.4 7.1 1.4 8.8 4.9 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein-like Amidohydro_4 PF13147.1 EGC32199.1 - 1.2e-18 68.2 0.0 1.7e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_1 PF01979.15 EGC32199.1 - 5.5e-16 59.1 0.1 1.9e-15 57.3 0.0 1.8 1 1 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGC32199.1 - 1.8e-10 40.4 4.6 2.4e-10 40.0 1.4 2.3 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGC32199.1 - 5.1e-06 25.9 0.8 0.001 18.4 0.0 2.4 1 1 1 2 2 2 2 Amidohydrolase family Amidohydro_2 PF04909.9 EGC32199.1 - 7.5e-06 25.6 0.0 1.1e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Amidohydrolase AP_endonuc_2 PF01261.19 EGC32199.1 - 0.03 13.6 0.1 0.052 12.8 0.0 1.4 1 0 0 1 1 1 0 Xylose isomerase-like TIM barrel PspB PF06667.7 EGC32200.1 - 0.68 9.9 4.8 19 5.2 0.1 3.0 2 0 0 2 2 2 0 Phage shock protein B OTU PF02338.14 EGC32201.1 - 1.2e-12 48.4 0.0 1.2e-12 48.4 0.0 2.9 2 1 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC32201.1 - 0.3 9.2 50.8 0.42 8.7 35.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 EGC32201.1 - 0.34 10.3 17.6 0.52 9.7 12.2 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.5 EGC32201.1 - 4 5.5 70.9 5.2 5.1 49.1 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Peptidase_M20 PF01546.23 EGC32203.1 - 5.3e-27 94.5 0.0 6.5e-27 94.2 0.0 1.1 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC32203.1 - 5.4e-12 45.4 0.0 1.2e-11 44.3 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGC32203.1 - 0.0062 16.2 0.0 0.013 15.2 0.0 1.6 2 0 0 2 2 2 1 Peptidase family M28 Peptidase_M42 PF05343.9 EGC32203.1 - 0.038 12.7 0.0 0.056 12.1 0.0 1.3 1 0 0 1 1 1 0 M42 glutamyl aminopeptidase DUF3688 PF12461.3 EGC32203.1 - 0.077 13.3 1.9 0.17 12.2 0.9 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF3688) Methyltransf_16 PF10294.4 EGC32204.1 - 3.6e-17 62.3 0.1 7.5e-17 61.3 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGC32204.1 - 1.2e-09 37.9 0.6 1.2e-09 37.9 0.4 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC32204.1 - 2.2e-07 31.2 0.1 2.2e-07 31.2 0.1 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32204.1 - 4.8e-07 30.3 0.0 8.3e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32204.1 - 5.9e-07 29.3 0.1 1.3e-06 28.1 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC32204.1 - 0.0008 19.8 0.0 0.0017 18.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC32204.1 - 0.0021 17.4 0.1 0.0044 16.4 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC32204.1 - 0.011 15.8 0.0 0.017 15.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain NodS PF05401.6 EGC32204.1 - 0.011 15.1 0.0 0.026 13.8 0.0 1.6 1 1 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_25 PF13649.1 EGC32204.1 - 0.013 15.8 0.0 0.029 14.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain TehB PF03848.9 EGC32204.1 - 0.016 14.3 1.3 0.02 14.0 0.1 1.8 2 1 0 2 2 2 0 Tellurite resistance protein TehB NPHI_C PF08469.5 EGC32204.1 - 1.1 9.1 8.3 0.51 10.2 1.8 2.5 3 0 0 3 3 3 0 Nucleoside triphosphatase I C-terminal CarboxypepD_reg PF13620.1 EGC32205.1 - 2.4e-07 30.7 1.7 8.9e-06 25.6 0.1 2.7 2 0 0 2 2 2 1 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EGC32205.1 - 2.6e-06 27.0 0.7 7.2e-06 25.6 0.5 1.8 1 0 0 1 1 1 1 Cna protein B-type domain DUF4480 PF13715.1 EGC32205.1 - 0.00047 20.1 1.1 0.0014 18.5 0.1 2.3 2 0 0 2 2 2 1 Domain of unknown function (DUF4480) SapB_2 PF03489.12 EGC32206.1 - 1e-06 28.6 0.5 1e-06 28.6 0.4 2.3 2 1 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC32206.1 - 0.0001 21.9 1.4 0.0001 21.9 0.9 2.1 2 1 1 3 3 3 1 Saposin-like type B, region 1 DUF445 PF04286.7 EGC32206.1 - 0.057 12.9 0.0 0.073 12.5 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF445) PI-PLC-X PF00388.14 EGC32206.1 - 0.094 12.1 0.3 0.11 11.8 0.2 1.1 1 0 0 1 1 1 0 Phosphatidylinositol-specific phospholipase C, X domain Beach PF02138.13 EGC32207.1 - 9.1e-115 382.7 0.2 9.1e-115 382.7 0.2 4.2 4 1 0 5 5 5 1 Beige/BEACH domain WD40 PF00400.27 EGC32207.1 - 1.6e-17 62.5 13.7 1.1e-08 34.6 0.3 4.9 4 0 0 4 4 4 4 WD domain, G-beta repeat PH_BEACH PF14844.1 EGC32207.1 - 1.7e-12 47.1 2.1 3.7e-12 46.0 0.0 2.9 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH Kinetochor_Ybp2 PF08568.5 EGC32208.1 - 1.6e-16 59.7 0.7 1.4e-10 40.1 0.7 2.7 2 1 0 2 2 2 2 Uncharacterised protein family, YAP/Alf4/glomulin CDC45 PF02724.9 EGC32208.1 - 0.07 11.1 24.6 0.1 10.6 1.2 2.7 3 0 0 3 3 3 0 CDC45-like protein Nop14 PF04147.7 EGC32208.1 - 0.87 7.4 43.5 0.026 12.4 4.8 3.3 4 0 0 4 4 4 0 Nop14-like family DUF2363 PF10155.4 EGC32209.1 - 0.035 14.0 0.1 0.071 13.0 0.1 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2363) Dimer_Tnp_hAT PF05699.9 EGC32211.1 - 2.5e-13 49.4 0.2 3e-13 49.2 0.2 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Pinin_SDK_memA PF04696.8 EGC32212.1 - 0.19 11.3 27.2 0.26 10.9 18.9 1.1 1 0 0 1 1 1 0 pinin/SDK/memA/ protein conserved region Amino_oxidase PF01593.19 EGC32212.1 - 0.38 9.7 1.8 0.37 9.7 1.2 1.1 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Dendrin PF15498.1 EGC32212.1 - 1.5 7.2 6.8 1.7 7.0 4.7 1.0 1 0 0 1 1 1 0 Nephrin and CD2AP-binding protein, Dendrin Fmp27_WPPW PF10359.4 EGC32212.1 - 2.4 6.4 22.4 2.5 6.4 15.5 1.0 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain DDRGK PF09756.4 EGC32212.1 - 2.6 7.3 34.0 3.2 7.1 23.6 1.1 1 0 0 1 1 1 0 DDRGK domain DUF1168 PF06658.7 EGC32212.1 - 4.1 6.9 29.0 4.7 6.7 20.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1168) FAM60A PF15396.1 EGC32212.1 - 6 6.5 16.0 7 6.3 11.1 1.1 1 0 0 1 1 1 0 Protein Family FAM60A DUF1510 PF07423.6 EGC32212.1 - 8.2 5.7 24.8 10 5.4 17.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Ank_4 PF13637.1 EGC32215.1 - 0.0011 19.3 0.7 6.7 7.3 0.1 3.8 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC32217.1 - 0.024 15.1 2.5 8.7 6.9 0.1 3.4 4 0 0 4 4 4 0 Ankyrin repeats (many copies) I_LWEQ PF01608.12 EGC32220.1 - 3.1e-07 30.4 1.2 1.9e-05 24.6 0.1 3.0 2 1 1 3 3 3 1 I/LWEQ domain IPI_T4 PF11634.3 EGC32221.1 - 0.12 12.2 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Nuclease inhibitor from bacteriophage T4 PAT1 PF09770.4 EGC32225.1 - 0.017 13.4 31.9 0.021 13.1 22.1 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1180 PF06679.7 EGC32225.1 - 0.23 11.3 0.0 0.23 11.3 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1180) PLRV_ORF5 PF01690.12 EGC32225.1 - 2.8 6.9 45.6 0.18 10.9 12.4 2.1 2 0 0 2 2 2 0 Potato leaf roll virus readthrough protein Med15 PF09606.5 EGC32225.1 - 2.8 6.0 43.7 3.8 5.5 30.3 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Macoilin PF09726.4 EGC32225.1 - 8.5 4.5 31.2 13 3.9 21.6 1.1 1 0 0 1 1 1 0 Transmembrane protein FNIP PF05725.7 EGC32226.1 - 6.4e-09 35.6 8.5 5.8e-07 29.3 1.1 4.3 3 2 2 5 5 5 2 FNIP Repeat zf-B_box PF00643.19 EGC32226.1 - 8.3e-06 25.5 4.5 1.5e-05 24.8 3.1 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC32226.1 - 0.011 15.4 3.2 0.024 14.3 2.2 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Sec20 PF03908.8 EGC32226.1 - 0.78 9.4 11.8 0.39 10.4 2.8 2.5 1 1 1 2 2 2 0 Sec20 zf-DBF PF07535.7 EGC32227.1 - 0.0071 15.9 1.2 0.019 14.5 0.9 1.8 1 0 0 1 1 1 1 DBF zinc finger Snurportin1 PF11538.3 EGC32227.1 - 0.044 13.5 3.4 0.087 12.6 2.3 1.5 1 0 0 1 1 1 0 Snurportin1 Myb_DNA-bind_4 PF13837.1 EGC32227.1 - 0.055 13.6 7.7 0.087 12.9 5.1 1.7 1 1 0 1 1 1 0 Myb/SANT-like DNA-binding domain zf-HC5HC2H PF13771.1 EGC32227.1 - 0.091 12.9 3.4 0.15 12.2 1.7 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain GEMIN8 PF15348.1 EGC32227.1 - 0.9 9.5 12.2 1.2 9.1 8.5 1.1 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 PRO8NT PF08082.6 EGC32227.1 - 5.3 6.6 8.5 3.2 7.3 1.9 2.0 1 1 1 2 2 2 0 PRO8NT (NUC069), PrP8 N-terminal domain WBS_methylT PF12589.3 EGC32228.1 - 0.23 11.9 4.8 0.34 11.4 3.3 1.4 1 0 0 1 1 1 0 Methyltransferase involved in Williams-Beuren syndrome DUF4652 PF15525.1 EGC32228.1 - 0.71 9.2 16.6 0.84 9.0 11.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4652) Secretin_N_2 PF07655.8 EGC32228.1 - 4.6 7.6 21.7 5.7 7.3 15.0 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain CobT PF06213.7 EGC32228.1 - 5 6.1 8.4 5.5 6.0 5.9 1.0 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT NAD_binding_5 PF07994.7 EGC32229.1 - 7.4e-111 370.3 0.1 8.8e-111 370.1 0.1 1.1 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase Inos-1-P_synth PF01658.12 EGC32229.1 - 8.5e-48 160.8 0.1 1.7e-47 159.8 0.1 1.5 1 0 0 1 1 1 1 Myo-inositol-1-phosphate synthase BRO1 PF03097.13 EGC32230.1 - 6.1e-23 81.1 0.1 7.6e-23 80.8 0.1 1.0 1 0 0 1 1 1 1 BRO1-like domain MFS_1 PF07690.11 EGC32231.1 - 8.4e-19 67.4 11.7 8.4e-19 67.4 8.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily AAA_23 PF13476.1 EGC32233.1 - 2.2e-05 24.8 9.1 2.2e-05 24.8 6.3 5.0 3 2 1 4 4 3 1 AAA domain MMR_HSR1 PF01926.18 EGC32233.1 - 2.5e-05 24.2 1.9 0.00036 20.4 0.0 3.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC32233.1 - 0.00034 19.8 0.0 0.00034 19.8 0.0 2.4 2 0 0 2 2 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC32233.1 - 0.0021 17.5 1.4 0.012 15.0 0.0 2.8 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_33 PF13671.1 EGC32233.1 - 0.0026 17.6 0.1 0.01 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGC32233.1 - 0.0042 16.0 0.1 0.0083 15.0 0.0 1.4 1 0 0 1 1 1 1 Type II/IV secretion system protein MobB PF03205.9 EGC32233.1 - 0.0059 16.3 0.0 0.023 14.3 0.0 2.0 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B MORN PF02493.15 EGC32233.1 - 0.0077 15.9 1.6 0.026 14.2 0.0 2.5 2 0 0 2 2 2 1 MORN repeat AAA_22 PF13401.1 EGC32233.1 - 0.034 14.3 0.0 0.28 11.3 0.0 2.7 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGC32233.1 - 0.044 13.9 0.1 0.26 11.4 0.0 2.4 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGC32233.1 - 0.057 12.9 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC32233.1 - 0.28 11.4 0.1 0.28 11.4 0.0 2.8 3 1 0 3 3 3 0 ABC transporter Complex1_LYR_2 PF13233.1 EGC32233.1 - 5.1 7.6 6.5 52 4.4 0.1 2.9 2 0 0 2 2 2 0 Complex1_LYR-like AAA_23 PF13476.1 EGC32234.1 - 2.8e-06 27.7 4.5 2.8e-06 27.7 3.1 4.9 3 2 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EGC32234.1 - 8.2e-06 25.7 4.1 1.6e-05 24.8 0.1 3.3 2 2 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC32234.1 - 0.00017 20.8 0.0 0.00084 18.5 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC32234.1 - 0.00094 18.6 0.7 0.015 14.7 0.0 2.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MobB PF03205.9 EGC32234.1 - 0.0023 17.6 0.0 0.0073 16.0 0.0 1.8 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGC32234.1 - 0.0063 16.3 0.0 0.023 14.5 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC32234.1 - 0.014 15.5 0.1 0.12 12.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGC32234.1 - 0.014 14.3 0.0 0.033 13.0 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein ABC_tran PF00005.22 EGC32234.1 - 0.019 15.2 2.7 0.037 14.3 0.0 2.8 3 0 0 3 3 3 0 ABC transporter MORN PF02493.15 EGC32234.1 - 0.019 14.6 2.3 0.026 14.2 0.0 2.4 2 0 0 2 2 2 0 MORN repeat AAA_29 PF13555.1 EGC32234.1 - 0.023 14.2 0.0 0.059 12.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain PI3Ka PF00613.15 EGC32235.1 - 1.6e-60 203.4 1.1 3e-60 202.5 0.7 1.4 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC32235.1 - 2.3e-51 174.5 0.0 2.1e-50 171.3 0.0 2.2 1 1 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGC32235.1 - 2.1e-36 124.8 0.1 4.2e-36 123.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 DUF3430 PF11912.3 EGC32236.1 - 3.2e-13 49.9 35.1 4.1e-13 49.6 24.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC32236.1 - 0.00013 21.9 2.6 0.00013 21.9 1.8 3.4 2 2 0 3 3 3 1 Protein of unknown function (DUF3586) GTP_EFTU PF00009.22 EGC32237.1 - 8.7e-58 194.8 0.1 1.2e-57 194.4 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGC32237.1 - 2.9e-25 88.3 0.1 2.2e-24 85.5 0.0 2.3 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGC32237.1 - 4.7e-15 55.4 1.5 9.9e-15 54.4 1.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC32237.1 - 2.2e-05 24.3 0.0 4.1e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGC32237.1 - 4.6e-05 22.9 0.5 0.00012 21.6 0.3 1.7 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EGC32237.1 - 0.01 16.3 0.0 0.02 15.3 0.0 1.5 1 0 0 1 1 1 0 Miro-like protein MobB PF03205.9 EGC32237.1 - 0.062 13.0 0.3 0.22 11.1 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B PTEN_C2 PF10409.4 EGC32238.1 - 3.1e-16 59.3 0.5 5.9e-16 58.4 0.3 1.5 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein Y_phosphatase PF00102.22 EGC32238.1 - 1.1e-11 44.6 0.5 1.8e-11 43.8 0.0 1.6 2 0 0 2 2 2 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGC32238.1 - 1.1e-10 41.2 0.0 2.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGC32238.1 - 0.00038 20.7 0.0 0.00092 19.4 0.0 1.5 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGC32238.1 - 0.037 14.0 0.0 0.074 13.0 0.0 1.5 1 0 0 1 1 1 0 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EGC32238.1 - 0.075 12.3 0.0 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family B_lectin PF01453.19 EGC32239.1 - 8.3e-17 61.1 0.2 1.1e-09 38.1 0.1 2.1 1 1 1 2 2 2 2 D-mannose binding lectin IN_DBD_C PF00552.16 EGC32239.1 - 0.0021 17.4 0.0 0.0044 16.4 0.0 1.5 1 0 0 1 1 1 1 Integrase DNA binding domain Pkinase PF00069.20 EGC32242.1 - 1e-55 188.7 1.8 3.6e-55 186.9 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32242.1 - 1.5e-50 171.7 0.0 4.1e-50 170.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase CD20 PF04103.10 EGC32242.1 - 0.032 14.1 0.1 0.032 14.1 0.1 2.8 3 0 0 3 3 3 0 CD20-like family Kdo PF06293.9 EGC32242.1 - 0.053 12.5 0.0 0.11 11.5 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RCR PF12273.3 EGC32242.1 - 0.088 13.3 0.2 0.088 13.3 0.1 4.4 3 1 1 4 4 4 0 Chitin synthesis regulation, resistance to Congo red OAD_gamma PF04277.8 EGC32242.1 - 1.2 9.5 2.0 5.4 7.4 0.0 2.9 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain EphA2_TM PF14575.1 EGC32242.1 - 1.9 8.9 0.0 1.9 8.9 0.0 3.3 3 1 1 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain BUD22 PF09073.5 EGC32243.1 - 0.0013 17.9 101.8 0.0016 17.5 43.2 3.2 1 1 2 3 3 3 2 BUD22 Nop PF01798.13 EGC32244.1 - 2.3e-36 124.3 0.1 4.5e-36 123.4 0.0 1.5 1 0 0 1 1 1 1 Putative snoRNA binding domain Prp31_C PF09785.4 EGC32244.1 - 6.9e-29 100.7 4.1 1.7e-28 99.5 2.8 1.7 1 0 0 1 1 1 1 Prp31 C terminal domain NOSIC PF08060.8 EGC32244.1 - 1.6e-16 59.8 2.4 1.7e-16 59.7 0.4 2.0 2 0 0 2 2 2 1 NOSIC (NUC001) domain Sec39 PF08314.6 EGC32244.1 - 0.0025 15.8 0.8 0.0025 15.8 0.5 1.6 2 0 0 2 2 2 1 Secretory pathway protein Sec39 DUF1635 PF07795.6 EGC32244.1 - 0.24 10.7 5.2 4.5 6.5 1.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1635) RRN3 PF05327.6 EGC32245.1 - 4.8e-92 308.8 19.2 2.3e-51 174.6 1.6 3.9 3 1 0 3 3 3 2 RNA polymerase I specific transcription initiation factor RRN3 GATA PF00320.22 EGC32246.1 - 2e-14 52.6 6.9 4.1e-14 51.6 4.8 1.6 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 EGC32246.1 - 0.37 10.6 5.4 1.2 8.9 3.7 2.0 1 1 0 1 1 1 0 Double zinc ribbon SNARE_assoc PF09335.6 EGC32247.1 - 1.3e-12 47.9 5.8 1.3e-12 47.9 4.0 1.9 2 1 0 2 2 2 1 SNARE associated Golgi protein DPM3 PF08285.6 EGC32247.1 - 0.0001 22.0 0.0 0.0001 22.0 0.0 2.1 3 0 0 3 3 3 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) FixP_N PF14715.1 EGC32247.1 - 0.0014 18.0 2.9 0.0037 16.6 0.0 2.6 2 0 0 2 2 2 1 N-terminal domain of cytochrome oxidase-cbb3, FixP RasGEF PF00617.14 EGC32248.1 - 3.1e-42 144.4 3.8 9.7e-42 142.8 2.7 1.9 1 0 0 1 1 1 1 RasGEF domain LRR_4 PF12799.2 EGC32248.1 - 1.6e-26 91.4 61.5 9.3e-07 28.3 2.4 7.8 5 1 3 8 8 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC32248.1 - 6.8e-19 67.3 51.1 2.7e-06 27.0 4.2 6.8 5 1 1 6 6 6 5 Leucine rich repeat LRR_1 PF00560.28 EGC32248.1 - 9.4e-13 46.3 51.3 0.22 11.6 0.2 13.3 12 0 0 12 12 12 6 Leucine Rich Repeat RasGEF_N PF00618.15 EGC32248.1 - 3.5e-11 43.1 2.7 2.2e-10 40.5 1.9 2.5 1 0 0 1 1 1 1 RasGEF N-terminal motif LRR_7 PF13504.1 EGC32248.1 - 3.7e-05 23.2 38.2 2 8.9 0.1 10.5 10 0 0 10 10 10 4 Leucine rich repeat ABC2_membrane PF01061.19 EGC32249.1 - 1.8e-86 288.6 60.9 2.5e-48 164.0 15.1 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC32249.1 - 7.9e-49 165.4 0.1 3.8e-23 82.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_21 PF13304.1 EGC32249.1 - 5.4e-11 42.9 8.8 9.1e-06 25.8 0.6 5.3 4 2 0 4 4 3 2 AAA domain AAA_15 PF13175.1 EGC32249.1 - 5.7e-08 32.2 0.7 0.72 8.8 0.2 4.7 3 1 2 5 5 4 3 AAA ATPase domain AAA_16 PF13191.1 EGC32249.1 - 7.1e-08 32.6 0.0 0.0024 17.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGC32249.1 - 1.1e-07 31.2 0.1 0.002 17.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC32249.1 - 1.7e-07 31.4 0.5 0.031 14.4 0.1 3.0 2 2 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGC32249.1 - 5e-07 29.6 0.0 0.026 14.4 0.0 2.4 2 0 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGC32249.1 - 1.1e-06 28.0 0.0 0.03 13.5 0.0 2.8 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGC32249.1 - 1.1e-06 28.1 0.0 0.05 12.9 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGC32249.1 - 2.7e-06 27.7 1.0 0.028 14.7 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EGC32249.1 - 3.1e-06 27.9 0.0 0.11 13.3 0.0 2.7 2 0 0 2 2 2 2 AAA domain Arch_ATPase PF01637.13 EGC32249.1 - 4.7e-06 26.4 0.0 0.13 11.9 0.0 2.8 2 0 0 2 2 2 2 Archaeal ATPase AAA_29 PF13555.1 EGC32249.1 - 6.7e-06 25.5 0.3 0.0029 17.1 0.0 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_23 PF13476.1 EGC32249.1 - 9.3e-06 26.0 2.2 0.77 10.0 0.0 3.4 2 1 1 3 3 3 2 AAA domain AAA PF00004.24 EGC32249.1 - 1.8e-05 24.9 0.0 0.012 15.8 0.0 2.7 3 0 0 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGC32249.1 - 2.1e-05 24.5 0.2 0.17 11.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGC32249.1 - 2.2e-05 24.5 0.1 0.26 11.4 0.0 3.3 3 0 0 3 3 3 2 RNA helicase MMR_HSR1 PF01926.18 EGC32249.1 - 0.00014 21.7 0.0 0.83 9.6 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGC32249.1 - 0.0003 20.6 0.0 0.12 12.2 0.0 2.9 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit UPF0079 PF02367.12 EGC32249.1 - 0.00043 19.9 0.2 0.49 10.0 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Rad17 PF03215.10 EGC32249.1 - 0.0006 18.6 0.0 1 7.9 0.0 2.4 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein IstB_IS21 PF01695.12 EGC32249.1 - 0.0007 19.0 0.0 1.1 8.6 0.0 2.9 3 0 0 3 3 3 1 IstB-like ATP binding protein PDR_CDR PF06422.7 EGC32249.1 - 0.00081 19.0 3.9 0.24 11.0 0.3 2.8 2 0 0 2 2 2 2 CDR ABC transporter Zeta_toxin PF06414.7 EGC32249.1 - 0.0015 17.7 0.1 0.2 10.7 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_19 PF13245.1 EGC32249.1 - 0.0016 18.1 0.1 0.69 9.7 0.0 2.4 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EGC32249.1 - 0.0018 17.9 0.5 1.8 8.2 0.0 2.5 2 0 0 2 2 2 1 NACHT domain cobW PF02492.14 EGC32249.1 - 0.0027 17.2 0.6 0.89 8.9 0.1 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_5 PF07728.9 EGC32249.1 - 0.0034 17.1 0.2 0.84 9.3 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) DUF815 PF05673.8 EGC32249.1 - 0.0038 16.1 0.1 0.064 12.1 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Miro PF08477.8 EGC32249.1 - 0.0049 17.3 0.0 1.1 9.7 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EGC32249.1 - 0.0077 15.7 0.4 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EGC32249.1 - 0.0086 15.6 0.1 4.2 6.8 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGC32249.1 - 0.01 15.7 0.0 5 7.0 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EGC32249.1 - 0.012 14.6 56.4 0.19 10.7 20.0 3.8 3 1 1 4 4 4 0 ABC-2 family transporter protein AAA_24 PF13479.1 EGC32249.1 - 0.013 15.1 1.5 0.46 10.0 0.0 2.6 3 0 0 3 3 2 0 AAA domain SRPRB PF09439.5 EGC32249.1 - 0.036 13.2 0.1 0.2 10.8 0.0 2.1 2 0 0 2 2 2 0 Signal recognition particle receptor beta subunit NTPase_1 PF03266.10 EGC32249.1 - 0.059 13.0 0.5 32 4.1 0.0 3.2 3 0 0 3 3 3 0 NTPase ATP-synt_ab PF00006.20 EGC32249.1 - 0.072 12.5 0.0 0.38 10.2 0.0 2.0 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain ArgK PF03308.11 EGC32249.1 - 0.097 11.4 0.2 3.9 6.1 0.0 2.2 2 0 0 2 2 2 0 ArgK protein MobB PF03205.9 EGC32249.1 - 0.12 12.0 0.5 5.2 6.7 0.0 3.0 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B FeoB_N PF02421.13 EGC32249.1 - 0.12 11.6 0.1 2 7.7 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_10 PF12846.2 EGC32249.1 - 0.13 11.6 0.5 5.2 6.4 0.1 2.4 2 0 0 2 2 2 0 AAA-like domain DUF3753 PF12575.3 EGC32249.1 - 0.19 11.5 3.8 0.21 11.4 0.4 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Sigma54_activ_2 PF14532.1 EGC32249.1 - 0.2 11.6 0.1 2.7 8.0 0.0 2.5 3 0 0 3 3 2 0 Sigma-54 interaction domain T2SE PF00437.15 EGC32249.1 - 0.21 10.4 0.0 7.4 5.3 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGC32249.1 - 0.23 10.9 0.0 2.7 7.4 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_11 PF13086.1 EGC32249.1 - 0.36 10.3 1.1 0.54 9.7 0.0 1.8 2 0 0 2 2 1 0 AAA domain PDR_assoc PF08370.6 EGC32249.1 - 6.1 6.4 16.4 0.13 11.7 0.1 3.6 4 0 0 4 4 2 0 Plant PDR ABC transporter associated DUF4457 PF14652.1 EGC32250.1 - 1.1e-159 530.8 10.5 6.2e-125 416.5 2.3 5.3 5 1 1 6 6 6 3 Domain of unknown function (DUF4457) Flavokinase PF01687.12 EGC32251.1 - 2.5e-36 124.3 0.0 2.9e-36 124.1 0.0 1.1 1 0 0 1 1 1 1 Riboflavin kinase ABC2_membrane PF01061.19 EGC32253.1 - 1.7e-83 278.9 52.3 1.9e-44 151.3 12.0 2.8 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC32253.1 - 1.2e-50 171.3 1.2 9.9e-25 87.4 0.1 2.5 2 0 0 2 2 2 2 ABC transporter Arch_ATPase PF01637.13 EGC32253.1 - 3.3e-09 36.8 0.1 8.7e-05 22.3 0.0 2.5 2 0 0 2 2 2 2 Archaeal ATPase DUF258 PF03193.11 EGC32253.1 - 7.6e-09 34.9 0.2 0.0022 17.2 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC32253.1 - 8.2e-09 35.1 0.0 0.0013 18.1 0.0 2.9 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGC32253.1 - 1.6e-08 34.7 0.1 0.0059 16.7 0.0 2.7 2 1 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGC32253.1 - 5.8e-08 32.2 1.1 0.00051 19.3 0.1 2.5 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGC32253.1 - 8.4e-08 32.4 0.0 0.011 15.7 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_21 PF13304.1 EGC32253.1 - 1.1e-06 28.8 0.3 0.00014 21.9 0.1 6.3 4 2 1 5 5 3 2 AAA domain AAA_33 PF13671.1 EGC32253.1 - 2.6e-06 27.3 0.1 0.067 13.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGC32253.1 - 3.1e-06 26.5 0.5 0.003 17.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_28 PF13521.1 EGC32253.1 - 1.3e-05 25.2 0.2 0.095 12.6 0.0 2.4 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGC32253.1 - 2.3e-05 24.5 0.0 0.47 10.6 0.0 3.0 2 0 0 2 2 2 2 RNA helicase AAA_17 PF13207.1 EGC32253.1 - 2.3e-05 25.1 0.0 0.1 13.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain MMR_HSR1 PF01926.18 EGC32253.1 - 4.8e-05 23.2 0.0 0.33 10.9 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EGC32253.1 - 5.5e-05 23.3 0.1 0.13 12.4 0.0 3.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) PDR_assoc PF08370.6 EGC32253.1 - 0.00016 21.1 1.1 0.013 14.9 0.1 3.1 2 0 0 2 2 2 1 Plant PDR ABC transporter associated NACHT PF05729.7 EGC32253.1 - 0.00018 21.2 0.4 0.16 11.5 0.0 2.4 2 0 0 2 2 2 2 NACHT domain cobW PF02492.14 EGC32253.1 - 0.0004 19.8 1.1 0.66 9.3 0.1 2.3 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain UPF0079 PF02367.12 EGC32253.1 - 0.00043 19.9 0.9 0.29 10.7 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 PDR_CDR PF06422.7 EGC32253.1 - 0.00067 19.2 3.8 0.29 10.8 0.3 2.6 2 0 0 2 2 2 2 CDR ABC transporter AAA_18 PF13238.1 EGC32253.1 - 0.00075 19.8 4.4 0.52 10.6 0.0 3.3 3 0 0 3 3 2 2 AAA domain AAA_19 PF13245.1 EGC32253.1 - 0.00094 18.8 0.4 0.9 9.3 0.0 3.0 2 1 1 3 3 3 1 Part of AAA domain Septin PF00735.13 EGC32253.1 - 0.0014 17.7 0.2 0.18 10.7 0.0 2.4 2 0 0 2 2 2 1 Septin AAA_5 PF07728.9 EGC32253.1 - 0.0018 17.9 0.5 0.39 10.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGC32253.1 - 0.0023 17.8 0.0 3.8 7.4 0.0 2.8 2 0 0 2 2 2 0 AAA domain ABC2_membrane_3 PF12698.2 EGC32253.1 - 0.0034 16.4 18.4 0.0034 16.4 12.8 3.2 2 2 0 2 2 2 1 ABC-2 family transporter protein Miro PF08477.8 EGC32253.1 - 0.0046 17.4 0.0 1.3 9.5 0.0 2.8 2 0 0 2 2 2 1 Miro-like protein Zeta_toxin PF06414.7 EGC32253.1 - 0.0055 15.8 0.0 0.94 8.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin IstB_IS21 PF01695.12 EGC32253.1 - 0.0065 15.9 0.1 4.3 6.7 0.0 2.6 2 1 0 2 2 2 0 IstB-like ATP binding protein AAA_10 PF12846.2 EGC32253.1 - 0.0066 15.9 2.5 3.4 7.0 0.1 3.1 3 0 0 3 3 3 1 AAA-like domain SbcCD_C PF13558.1 EGC32253.1 - 0.0068 16.3 0.1 0.13 12.2 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit PduV-EutP PF10662.4 EGC32253.1 - 0.0093 15.4 0.7 2.2 7.7 0.0 2.4 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation AAA_30 PF13604.1 EGC32253.1 - 0.012 15.1 0.1 5.7 6.4 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC32253.1 - 0.02 14.4 2.2 0.92 9.0 0.1 3.1 3 0 0 3 3 3 0 AAA domain FeoB_N PF02421.13 EGC32253.1 - 0.042 13.1 0.6 0.59 9.4 0.1 2.5 2 0 0 2 2 2 0 Ferrous iron transport protein B DUF815 PF05673.8 EGC32253.1 - 0.059 12.2 1.4 0.54 9.1 0.1 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF815) Sigma54_activ_2 PF14532.1 EGC32253.1 - 0.062 13.3 0.1 0.74 9.8 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EGC32253.1 - 0.075 12.5 0.4 0.68 9.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EGC32253.1 - 0.13 11.0 0.3 4.2 6.0 0.1 2.7 2 1 1 3 3 3 0 ArgK protein RuvB_N PF05496.7 EGC32253.1 - 0.18 10.8 0.4 5.3 6.0 0.0 2.4 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus SRP54 PF00448.17 EGC32253.1 - 0.2 11.0 1.4 20 4.5 0.0 3.0 2 1 1 3 3 3 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EGC32253.1 - 0.85 8.7 3.6 3.5 6.7 0.2 2.6 2 1 0 2 2 2 0 Magnesium chelatase, subunit ChlI WD40 PF00400.27 EGC32254.1 - 2.3e-74 242.8 26.5 6.7e-08 32.1 0.1 12.8 13 0 0 13 13 13 11 WD domain, G-beta repeat CHCH PF06747.8 EGC32255.1 - 0.00089 19.1 4.7 0.0017 18.1 3.2 1.5 1 0 0 1 1 1 1 CHCH domain zinc-ribbons_6 PF07191.7 EGC32255.1 - 0.5 10.1 5.2 0.24 11.2 0.7 1.9 1 1 0 1 1 1 0 zinc-ribbons Cupin_8 PF13621.1 EGC32256.1 - 4.6e-30 104.9 1.5 6.5e-30 104.4 1.0 1.1 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGC32256.1 - 7.5e-06 26.1 0.1 3.9e-05 23.8 0.1 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 EGC32256.1 - 0.004 16.6 0.0 0.0062 15.9 0.0 1.2 1 0 0 1 1 1 1 Cupin HEAT_2 PF13646.1 EGC32257.1 - 7.4e-06 26.1 0.4 0.0061 16.8 0.0 3.1 1 1 2 3 3 3 2 HEAT repeats HEAT PF02985.17 EGC32257.1 - 0.00013 21.7 0.5 0.015 15.3 0.0 3.8 4 0 0 4 4 4 1 HEAT repeat Adaptin_N PF01602.15 EGC32257.1 - 0.00016 20.1 0.8 0.00024 19.5 0.6 1.2 1 0 0 1 1 1 1 Adaptin N terminal region RasGEF_N_2 PF14663.1 EGC32257.1 - 0.059 13.3 0.2 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 Rapamycin-insensitive companion of mTOR RasGEF_N domain Arm PF00514.18 EGC32257.1 - 0.063 13.1 0.2 4.3 7.3 0.0 3.4 3 0 0 3 3 3 0 Armadillo/beta-catenin-like repeat Caa3_CtaG PF09678.5 EGC32257.1 - 0.091 11.6 0.6 0.19 10.6 0.4 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) HEAT_EZ PF13513.1 EGC32257.1 - 0.38 11.2 3.5 32 5.1 0.0 3.5 2 2 1 3 3 3 0 HEAT-like repeat NMT PF01233.14 EGC32258.1 - 3.8e-81 270.4 0.1 6.9e-81 269.6 0.1 1.4 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, N-terminal domain NMT_C PF02799.10 EGC32258.1 - 2.1e-70 235.9 3.2 4.1e-70 235.0 2.2 1.5 1 0 0 1 1 1 1 Myristoyl-CoA:protein N-myristoyltransferase, C-terminal domain Acetyltransf_9 PF13527.1 EGC32258.1 - 0.00031 20.5 0.0 0.0047 16.7 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC32258.1 - 0.091 12.9 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain SPG48 PF14764.1 EGC32261.1 - 0.0076 14.7 0.4 0.011 14.1 0.3 1.1 1 0 0 1 1 1 1 AP-5 complex subunit, vesicle trafficking PEX11 PF05648.9 EGC32263.1 - 7.1e-57 192.2 3.9 8.1e-57 192.0 2.7 1.0 1 0 0 1 1 1 1 Peroxisomal biogenesis factor 11 (PEX11) HPS3_N PF14761.1 EGC32263.1 - 0.015 14.6 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 Hermansky-Pudlak syndrome 3 RasGEF PF00617.14 EGC32264.1 - 5.1e-59 199.1 0.1 5.1e-59 199.1 0.1 2.4 3 0 0 3 3 3 1 RasGEF domain LRR_4 PF12799.2 EGC32264.1 - 3.1e-37 125.5 57.5 5.4e-10 38.6 0.8 8.4 4 1 5 9 9 9 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC32264.1 - 7.2e-35 118.5 58.1 3.8e-09 36.1 3.6 7.5 2 2 7 9 9 9 9 Leucine rich repeat RasGEF_N PF00618.15 EGC32264.1 - 4.2e-19 68.5 0.1 4.2e-19 68.5 0.1 3.9 4 0 0 4 4 4 1 RasGEF N-terminal motif LRR_1 PF00560.28 EGC32264.1 - 8.6e-18 61.6 47.2 0.088 12.8 0.1 13.7 13 0 0 13 13 12 7 Leucine Rich Repeat LRR_7 PF13504.1 EGC32264.1 - 1.1e-12 45.9 33.2 3.7 8.1 0.0 12.4 12 0 0 12 12 12 4 Leucine rich repeat LRR_9 PF14580.1 EGC32264.1 - 0.00026 20.5 14.6 0.005 16.4 0.7 4.2 1 1 2 4 4 4 3 Leucine-rich repeat LRR_3 PF07725.7 EGC32264.1 - 0.033 13.9 3.2 11 6.0 0.3 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat DUF2453 PF10507.4 EGC32264.1 - 0.2 11.5 0.9 0.49 10.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2453) LRR_6 PF13516.1 EGC32264.1 - 0.29 11.3 42.9 7 7.0 0.2 11.6 12 0 0 12 12 11 0 Leucine Rich repeat IQ PF00612.22 EGC32264.1 - 0.46 10.2 8.7 1.3 8.8 2.0 2.7 2 0 0 2 2 2 0 IQ calmodulin-binding motif UCH PF00443.24 EGC32265.1 - 1.9e-40 138.7 28.8 1.9e-40 138.7 20.0 3.4 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC32265.1 - 2.4e-23 83.0 3.0 2.4e-20 73.1 0.1 4.7 3 2 1 4 4 4 2 Ubiquitin carboxyl-terminal hydrolase CBS PF00571.23 EGC32266.1 - 3e-34 116.5 2.0 3.2e-17 62.0 0.1 2.2 2 0 0 2 2 2 2 CBS domain PRC PF05239.11 EGC32266.1 - 7.7e-05 22.4 0.1 0.012 15.4 0.0 2.2 2 0 0 2 2 2 2 PRC-barrel domain DUF3659 PF12396.3 EGC32266.1 - 0.019 14.6 0.6 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3659) PPV_E1_C PF00519.12 EGC32267.1 - 0.021 13.4 0.3 0.026 13.1 0.2 1.1 1 0 0 1 1 1 0 Papillomavirus helicase Ras PF00071.17 EGC32269.1 - 2.1e-58 196.3 1.8 2.6e-58 195.9 1.2 1.1 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGC32269.1 - 1e-20 73.6 1.0 1.3e-20 73.3 0.7 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC32269.1 - 1.5e-20 73.8 0.2 3.2e-20 72.8 0.1 1.5 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC32269.1 - 1.2e-07 31.1 0.3 1.5e-07 30.7 0.2 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC32269.1 - 3.1e-07 30.0 0.5 4.1e-06 26.3 0.2 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC32269.1 - 3.6e-06 26.3 3.0 2.2e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC32269.1 - 4.5e-05 23.3 0.1 8.6e-05 22.4 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGC32269.1 - 0.00046 20.2 0.1 0.65 9.9 0.0 2.3 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGC32269.1 - 0.0017 18.4 0.5 0.24 11.5 0.4 2.5 1 1 0 1 1 1 1 AAA domain FeoB_N PF02421.13 EGC32269.1 - 0.018 14.3 0.1 0.21 10.8 0.0 2.0 2 0 0 2 2 2 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC32269.1 - 0.025 14.0 0.1 0.094 12.2 0.0 2.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DNA_pol3_delta2 PF13177.1 EGC32269.1 - 0.025 14.2 0.2 1.3 8.6 0.0 2.0 1 1 0 2 2 2 0 DNA polymerase III, delta subunit HSDR_N_2 PF13588.1 EGC32269.1 - 0.031 14.0 0.9 5.3 6.8 0.0 2.3 2 0 0 2 2 2 0 Type I restriction enzyme R protein N terminus (HSDR_N) AAA PF00004.24 EGC32269.1 - 0.035 14.3 0.3 0.13 12.4 0.0 2.1 1 1 1 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGC32269.1 - 0.043 13.4 0.4 0.1 12.2 0.1 1.8 1 1 0 1 1 1 0 AAA domain OTCace_N PF02729.16 EGC32269.1 - 0.063 12.9 0.1 0.088 12.4 0.1 1.3 1 0 0 1 1 1 0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain G-alpha PF00503.15 EGC32269.1 - 0.13 10.8 7.6 5.7 5.5 5.3 3.1 1 1 0 1 1 1 0 G-protein alpha subunit PEMT PF04191.8 EGC32270.1 - 6.5e-28 96.9 2.0 6.5e-28 96.9 1.4 2.1 2 0 0 2 2 2 1 Phospholipid methyltransferase ICMT PF04140.9 EGC32270.1 - 0.005 17.0 1.6 0.0055 16.8 0.1 1.9 2 1 1 3 3 3 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family FixQ PF05545.6 EGC32270.1 - 0.068 12.8 0.9 1.3 8.7 0.0 2.5 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ MnhB PF04039.8 EGC32270.1 - 0.33 11.0 3.9 0.11 12.5 0.8 1.6 2 0 0 2 2 2 0 Domain related to MnhB subunit of Na+/H+ antiporter Pho88 PF10032.4 EGC32272.1 - 6.2e-52 175.6 1.6 9e-52 175.0 1.1 1.2 1 0 0 1 1 1 1 Phosphate transport (Pho88) Ank_2 PF12796.2 EGC32273.1 - 1.5e-24 86.1 1.4 1.2e-10 41.5 0.1 4.5 2 1 3 5 5 5 4 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC32273.1 - 2.4e-14 53.0 2.7 0.00041 20.4 0.0 5.9 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC32273.1 - 2.9e-14 53.1 8.2 0.0033 17.8 0.0 6.2 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32273.1 - 1e-13 50.0 11.3 0.025 14.8 0.0 8.5 5 1 4 9 9 9 4 Ankyrin repeat Ank PF00023.25 EGC32273.1 - 1.1e-13 50.2 3.9 0.69 9.8 0.0 7.3 5 1 3 8 8 8 6 Ankyrin repeat TPR_1 PF00515.23 EGC32274.1 - 1.9e-08 33.5 0.4 0.004 16.6 0.1 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC32274.1 - 2.6e-08 33.3 2.4 6.2e-05 22.5 0.0 2.8 2 1 1 3 3 3 2 TPR repeat TPR_2 PF07719.12 EGC32274.1 - 2.9e-07 29.8 3.2 0.0043 16.8 0.1 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32274.1 - 6.3e-06 25.5 4.1 0.0062 16.2 0.1 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32274.1 - 2.1e-05 24.3 0.8 0.00037 20.3 0.1 2.8 2 1 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EGC32274.1 - 0.00044 19.1 2.2 0.012 14.4 0.3 2.2 1 1 1 2 2 2 2 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EGC32274.1 - 0.0035 17.1 0.0 0.0098 15.7 0.0 1.8 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32274.1 - 0.0037 17.9 0.0 3.7 8.3 0.0 2.9 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32274.1 - 0.0059 16.3 0.3 0.19 11.5 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32274.1 - 0.0067 16.5 4.5 0.64 10.3 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32274.1 - 0.008 16.4 0.0 4.9 7.5 0.0 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat RGS PF00615.14 EGC32274.1 - 0.014 15.4 1.4 0.072 13.1 1.0 2.3 1 0 0 1 1 1 0 Regulator of G protein signaling domain TPR_14 PF13428.1 EGC32274.1 - 0.015 15.9 0.0 2.3 9.0 0.0 3.0 2 1 1 3 3 3 0 Tetratricopeptide repeat gpUL132 PF11359.3 EGC32276.1 - 0.0031 16.8 0.5 0.0051 16.1 0.2 1.4 1 1 0 1 1 1 1 Glycoprotein UL132 DUF4271 PF14093.1 EGC32276.1 - 0.0065 16.1 1.2 0.0086 15.7 0.8 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4271) LtrA PF06772.6 EGC32276.1 - 0.0066 15.3 0.2 0.0072 15.2 0.2 1.1 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) Serinc PF03348.10 EGC32276.1 - 0.026 13.2 0.9 0.034 12.8 0.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) MFS_2 PF13347.1 EGC32276.1 - 0.034 12.5 0.0 0.037 12.4 0.0 1.0 1 0 0 1 1 1 0 MFS/sugar transport protein E1-E2_ATPase PF00122.15 EGC32276.1 - 0.035 13.1 0.2 0.046 12.7 0.1 1.1 1 0 0 1 1 1 0 E1-E2 ATPase NapE PF06796.6 EGC32276.1 - 0.048 12.9 0.6 0.26 10.6 0.0 2.0 2 0 0 2 2 2 0 Periplasmic nitrate reductase protein NapE DUF3671 PF12420.3 EGC32276.1 - 0.063 13.2 2.8 0.085 12.8 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function MFS_Mycoplasma PF07672.8 EGC32276.1 - 0.069 12.3 2.5 0.094 11.8 1.8 1.1 1 0 0 1 1 1 0 Mycoplasma MFS transporter Ni_hydr_CYTB PF01292.15 EGC32276.1 - 0.072 12.4 0.3 0.1 12.0 0.2 1.3 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 DUF872 PF05915.7 EGC32276.1 - 0.1 12.4 0.3 0.13 12.0 0.2 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) DUF202 PF02656.10 EGC32276.1 - 0.19 11.9 2.3 0.34 11.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF202) MARVEL PF01284.18 EGC32276.1 - 0.22 11.3 3.5 0.95 9.2 2.3 1.8 1 1 0 1 1 1 0 Membrane-associating domain Tetraspannin PF00335.15 EGC32276.1 - 0.49 9.6 9.4 0.02 14.2 2.6 1.5 2 0 0 2 2 2 0 Tetraspanin family HECT PF00632.20 EGC32277.1 - 2.4e-96 322.6 2.9 6e-96 321.3 2.0 1.7 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Arm PF00514.18 EGC32277.1 - 0.00056 19.6 1.6 10 6.0 0.0 4.9 3 1 1 4 4 4 1 Armadillo/beta-catenin-like repeat HEAT PF02985.17 EGC32277.1 - 0.0086 16.0 1.3 8.6 6.7 0.0 4.3 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGC32277.1 - 0.018 15.2 0.0 0.6 10.4 0.1 3.2 3 0 0 3 3 3 0 HEAT repeats SH PF01445.12 EGC32278.1 - 0.001 18.6 0.5 0.0016 18.0 0.3 1.4 1 0 0 1 1 1 1 Viral small hydrophobic protein 53-BP1_Tudor PF09038.5 EGC32278.1 - 0.059 13.1 0.1 0.074 12.8 0.0 1.2 1 0 0 1 1 1 0 Tumour suppressor p53-binding protein-1 Tudor CD24 PF14984.1 EGC32278.1 - 0.094 12.5 0.2 0.18 11.6 0.1 1.6 1 0 0 1 1 1 0 CD24 protein TraK PF06586.6 EGC32279.1 - 0.0018 17.4 0.1 0.005 16.0 0.0 1.7 1 0 0 1 1 1 1 TraK protein EGF_2 PF07974.8 EGC32279.1 - 0.0082 16.2 9.5 0.0082 16.2 6.6 2.6 2 0 0 2 2 2 1 EGF-like domain SKG6 PF08693.5 EGC32279.1 - 0.092 12.0 0.8 0.23 10.8 0.6 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TrkA_N PF02254.13 EGC32280.1 - 0.11 12.4 0.0 0.37 10.8 0.0 1.9 1 0 0 1 1 1 0 TrkA-N domain BAR PF03114.13 EGC32281.1 - 1.7e-15 57.1 20.8 1.9e-15 57.0 14.4 1.0 1 0 0 1 1 1 1 BAR domain Arfaptin PF06456.8 EGC32281.1 - 3.5e-09 36.3 18.9 4.3e-09 36.0 13.1 1.0 1 0 0 1 1 1 1 Arfaptin-like domain HALZ PF02183.13 EGC32281.1 - 0.0092 15.6 3.4 0.15 11.8 0.3 2.8 2 1 0 2 2 2 1 Homeobox associated leucine zipper PerC PF06069.6 EGC32281.1 - 0.063 13.3 2.9 8.5 6.4 0.0 3.4 2 1 1 3 3 3 0 PerC transcriptional activator BAR_2 PF10455.4 EGC32281.1 - 0.24 10.2 20.6 0.52 9.1 14.3 1.5 1 1 0 1 1 1 0 Bin/amphiphysin/Rvs domain for vesicular trafficking Cep57_MT_bd PF06657.8 EGC32281.1 - 0.47 10.4 5.1 0.25 11.2 0.5 2.7 2 2 0 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Wax2_C PF12076.3 EGC32281.1 - 2.1 8.0 5.7 0.42 10.3 0.4 2.2 2 1 0 2 2 2 0 WAX2 C-terminal domain DUF948 PF06103.6 EGC32281.1 - 2.6 7.9 8.1 1.8 8.4 0.3 3.6 2 2 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Big_3_4 PF13754.1 EGC32283.1 - 0.0044 17.2 4.0 0.0044 17.2 2.8 7.3 8 0 0 8 8 8 1 Bacterial Ig-like domain (group 3) Med29 PF11568.3 EGC32283.1 - 0.011 15.8 0.1 0.026 14.5 0.1 1.6 1 0 0 1 1 1 0 Mediator complex subunit 29 CW_binding_1 PF01473.15 EGC32283.1 - 9.7 6.5 9.0 0.97 9.6 0.6 3.1 2 0 0 2 2 2 0 Putative cell wall binding repeat G8 PF10162.4 EGC32284.1 - 7e-28 96.9 1.2 2e-27 95.4 0.8 1.8 1 0 0 1 1 1 1 G8 domain Glyoxalase_2 PF12681.2 EGC32285.1 - 0.033 14.8 0.0 0.039 14.5 0.0 1.1 1 0 0 1 1 1 0 Glyoxalase-like domain Glyoxalase PF00903.20 EGC32285.1 - 0.044 13.7 0.2 0.061 13.3 0.1 1.2 1 0 0 1 1 1 0 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily TIG PF01833.19 EGC32286.1 - 3.4e-14 52.5 17.9 3.3e-08 33.3 1.7 4.2 3 0 0 3 3 3 2 IPT/TIG domain EGF_2 PF07974.8 EGC32286.1 - 3.9e-12 46.1 74.6 0.0002 21.4 8.2 5.0 4 0 0 4 4 4 4 EGF-like domain Laminin_EGF PF00053.19 EGC32286.1 - 0.00077 19.3 57.4 0.014 15.3 5.5 4.8 3 1 0 4 4 4 4 Laminin EGF-like (Domains III and V) CDP-OH_P_transf PF01066.16 EGC32287.1 - 3.5e-17 62.5 9.8 9.5e-17 61.1 6.8 1.9 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase DUF812 PF05667.6 EGC32288.1 - 0.0019 16.7 10.1 0.0023 16.5 7.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF812) Med9 PF07544.8 EGC32288.1 - 0.0041 16.8 7.6 0.0095 15.6 5.1 1.8 1 1 0 1 1 1 1 RNA polymerase II transcription mediator complex subunit 9 SPX PF03105.14 EGC32288.1 - 0.0095 15.7 17.6 0.014 15.1 12.2 1.2 1 0 0 1 1 1 1 SPX domain Secretin_N_2 PF07655.8 EGC32288.1 - 0.018 15.4 22.1 0.018 15.4 15.3 2.2 2 0 0 2 2 2 0 Secretin N-terminal domain SlyX PF04102.7 EGC32288.1 - 0.086 13.2 5.5 0.25 11.7 2.4 2.6 2 1 0 2 2 2 0 SlyX Nebulin PF00880.13 EGC32288.1 - 0.11 12.1 0.6 0.11 12.1 0.4 2.9 3 0 0 3 3 3 0 Nebulin repeat PA26 PF04636.8 EGC32288.1 - 0.13 10.9 9.5 0.16 10.6 6.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) CAF-1_p150 PF11600.3 EGC32288.1 - 0.95 8.7 7.2 1.5 8.1 5.0 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF4613 PF15390.1 EGC32288.1 - 0.99 7.5 15.5 0.96 7.5 9.4 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4613) ACCA PF03255.9 EGC32288.1 - 1.1 8.8 6.7 1.8 8.1 3.7 2.0 1 1 1 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit Tropomyosin_1 PF12718.2 EGC32288.1 - 1.8 8.4 17.5 0.025 14.4 6.1 2.0 1 1 1 2 2 2 0 Tropomyosin like DUF2203 PF09969.4 EGC32288.1 - 2.8 8.1 5.1 17 5.6 0.9 2.4 1 1 1 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF3450 PF11932.3 EGC32288.1 - 5.9 6.0 12.1 4.1 6.6 7.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) BTB PF00651.26 EGC32289.1 - 1.5e-07 31.3 0.5 2e-05 24.5 0.0 2.4 1 1 1 2 2 2 2 BTB/POZ domain Secretin_N_2 PF07655.8 EGC32289.1 - 0.59 10.5 15.2 1.1 9.7 10.5 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC32289.1 - 1.2 9.2 5.7 2.7 8.1 3.9 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) AAA_11 PF13086.1 EGC32291.1 - 0.037 13.6 7.5 0.059 12.9 5.2 1.2 1 0 0 1 1 1 0 AAA domain BSMAP PF12280.3 EGC32291.1 - 1.7 8.4 11.5 9.6 6.0 8.0 1.9 1 1 0 1 1 1 0 Brain specific membrane anchored protein PH PF00169.24 EGC32291.1 - 3.1 8.0 10.7 2.4 8.4 0.1 3.0 2 1 1 3 3 3 0 PH domain PA28_beta PF02252.13 EGC32292.1 - 0.099 12.1 6.8 5 6.5 0.2 4.8 4 2 0 4 4 4 0 Proteasome activator pa28 beta subunit PA26 PF04636.8 EGC32293.1 - 3.1e-160 533.8 0.1 3.7e-160 533.5 0.1 1.0 1 0 0 1 1 1 1 PA26 p53-induced protein (sestrin) Pro_isomerase PF00160.16 EGC32294.1 - 3.3e-42 144.3 0.6 3.6e-42 144.1 0.4 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD ENTH PF01417.15 EGC32295.1 - 1.9e-13 50.3 11.0 2.7e-11 43.4 1.0 3.0 2 0 0 2 2 2 2 ENTH domain ANTH PF07651.11 EGC32295.1 - 0.00027 19.7 0.0 0.00027 19.7 0.0 3.2 3 1 1 4 4 4 1 ANTH domain YebO PF13974.1 EGC32295.1 - 1.6 8.5 13.7 0.27 11.0 5.3 2.9 2 0 0 2 2 2 0 YebO-like protein Utp14 PF04615.8 EGC32295.1 - 2.3 6.3 32.6 5.2 5.1 22.6 1.5 1 0 0 1 1 1 0 Utp14 protein UPF0556 PF10572.4 EGC32296.1 - 5.7e-29 100.3 0.0 6.1e-29 100.2 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0556 Histone PF00125.19 EGC32297.1 - 1.6e-21 76.1 0.1 2.3e-21 75.6 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC32297.1 - 0.00038 20.5 0.2 0.00055 20.0 0.1 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EGC32297.1 - 0.0066 16.2 0.1 0.0091 15.7 0.0 1.3 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CBFD_NFYB_HMF PF00808.18 EGC32297.1 - 0.015 15.3 0.0 0.023 14.7 0.0 1.2 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC32297.1 - 0.018 14.7 0.2 0.053 13.2 0.1 1.6 1 1 1 2 2 2 0 Bromodomain associated CENP-T PF15511.1 EGC32297.1 - 0.02 14.1 0.0 0.024 13.9 0.0 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Stomoxyn PF11585.3 EGC32297.1 - 0.15 11.8 0.3 2.5 7.9 0.1 2.2 2 0 0 2 2 2 0 Insect antimicrobial peptide, stomoxyn ThiS-like PF14453.1 EGC32298.1 - 0.085 12.7 1.3 0.79 9.6 0.1 2.7 3 0 0 3 3 3 0 ThiS-like ubiquitin Peptidase_M24 PF00557.19 EGC32300.1 - 5.1e-47 160.1 0.0 6.1e-47 159.8 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGC32300.1 - 0.00073 19.3 2.7 0.0015 18.3 1.9 1.6 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EGC32300.1 - 0.02 14.5 3.8 0.053 13.1 2.7 1.8 1 0 0 1 1 1 0 HIT zinc finger FNIP PF05725.7 EGC32301.1 - 1.1e-41 140.5 66.3 2.3e-09 37.0 0.1 8.2 3 2 4 8 8 8 7 FNIP Repeat Diphthamide_syn PF01866.12 EGC32302.1 - 5.2e-54 183.5 0.2 2.8e-33 115.4 0.0 2.1 2 0 0 2 2 2 2 Putative diphthamide synthesis protein 5_nucleotid PF05761.9 EGC32303.1 - 3.6e-180 599.3 2.7 4.2e-180 599.0 1.9 1.0 1 0 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EGC32303.1 - 0.012 15.8 0.0 2 8.6 0.0 2.8 2 0 0 2 2 2 0 Haloacid dehalogenase-like hydrolase Trypsin_2 PF13365.1 EGC32304.1 - 2.7e-22 79.0 0.2 9e-16 57.9 0.0 3.0 2 0 0 2 2 2 2 Trypsin-like peptidase domain Trypsin PF00089.21 EGC32304.1 - 1.3e-07 31.4 5.5 0.00074 19.1 2.2 4.1 2 1 0 2 2 2 2 Trypsin Peptidase_S46 PF10459.4 EGC32304.1 - 3.3e-07 29.1 7.9 0.015 13.7 0.0 4.2 4 0 0 4 4 4 3 Peptidase S46 Nucleoporin_FG PF13634.1 EGC32305.1 - 6.4e-20 71.4 92.6 8.4e-12 45.3 29.1 4.6 2 2 2 4 4 4 2 Nucleoporin FG repeat region UPF0184 PF03670.8 EGC32305.1 - 0.04 14.1 0.2 0.04 14.1 0.1 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0184) BLOC1_2 PF10046.4 EGC32305.1 - 1.2 9.2 6.6 1.4 9.1 0.4 3.0 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 OTU PF02338.14 EGC32306.1 - 1.1e-12 48.6 0.4 3.7e-12 46.8 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease NAD_kinase PF01513.16 EGC32307.1 - 9.9e-59 198.4 0.0 1.9e-58 197.5 0.0 1.4 1 0 0 1 1 1 1 ATP-NAD kinase TrbL PF04610.9 EGC32308.1 - 0.0092 15.6 0.7 0.015 14.9 0.5 1.3 1 0 0 1 1 1 1 TrbL/VirB6 plasmid conjugal transfer protein Ctr PF04145.10 EGC32308.1 - 0.14 12.2 3.6 0.9 9.5 0.2 2.3 2 0 0 2 2 2 0 Ctr copper transporter family DUF2232 PF09991.4 EGC32308.1 - 0.15 11.0 5.9 6.4 5.6 4.1 2.1 1 1 0 1 1 1 0 Predicted membrane protein (DUF2232) FixQ PF05545.6 EGC32308.1 - 2.3 7.9 9.1 0.25 11.0 1.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ DUF4131 PF13567.1 EGC32308.1 - 3.1 7.1 5.8 0.49 9.7 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF1673 PF07895.6 EGC32308.1 - 5.5 6.4 13.4 6.1 6.3 3.4 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) DUF4449 PF14613.1 EGC32309.1 - 0.011 15.6 11.0 0.011 15.6 7.6 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF4449) DUF4239 PF14023.1 EGC32309.1 - 0.15 11.4 1.1 0.39 10.0 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) Rubis-subs-bind PF09273.6 EGC32310.1 - 1.5e-22 79.8 0.4 4e-22 78.4 0.3 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding SET PF00856.23 EGC32310.1 - 1.5e-05 25.3 0.0 0.004 17.4 0.0 2.6 3 0 0 3 3 3 2 SET domain PI3Ka PF00613.15 EGC32311.1 - 4.7e-59 198.6 0.7 1.1e-58 197.4 0.5 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC32311.1 - 3e-48 164.3 0.1 7.2e-48 163.1 0.1 1.7 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGC32311.1 - 4.5e-17 62.1 0.0 9.8e-17 61.0 0.0 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EGC32311.1 - 7.8e-09 35.4 0.1 2.5e-08 33.8 0.1 1.9 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain SpoIISA_toxin PF14171.1 EGC32311.1 - 0.013 14.7 1.9 0.03 13.5 1.3 1.6 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF4135 PF13575.1 EGC32311.1 - 0.024 13.6 0.1 0.045 12.7 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4135) Aft1_HRR PF11787.3 EGC32312.1 - 5.2 8.1 15.7 15 6.7 0.5 2.5 2 0 0 2 2 2 0 Aft1 HRR domain SNAP PF14938.1 EGC32313.1 - 1.6e-13 50.4 5.1 3.7e-13 49.2 3.5 1.5 1 1 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGC32313.1 - 7.1e-12 45.1 3.0 7.6e-07 28.9 0.2 3.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC32313.1 - 7.4e-09 35.1 3.5 1.7e-06 27.6 1.4 3.7 2 1 1 3 3 3 1 TPR repeat TPR_1 PF00515.23 EGC32313.1 - 1.4e-06 27.6 4.2 0.00034 20.0 0.1 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32313.1 - 2.3e-06 27.0 3.9 0.00097 18.8 0.1 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32313.1 - 0.00038 20.0 6.2 0.0061 16.2 0.1 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC32313.1 - 0.0051 16.9 5.2 0.96 9.6 0.0 3.2 4 0 0 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGC32313.1 - 0.1 12.4 0.1 3 7.8 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat LIM PF00412.17 EGC32314.1 - 2.4e-17 62.7 26.4 6.4e-11 42.1 6.7 3.2 3 0 0 3 3 3 2 LIM domain RRM_5 PF13893.1 EGC32315.1 - 0.022 14.5 0.0 0.048 13.5 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sec3_C PF09763.4 EGC32316.1 - 4.1e-169 564.0 34.5 5.4e-169 563.6 23.9 1.1 1 0 0 1 1 1 1 Exocyst complex component Sec3 CCDC-167 PF15188.1 EGC32316.1 - 0.00043 20.1 0.3 0.0017 18.2 0.1 2.2 2 0 0 2 2 2 1 Coiled-coil domain-containing protein 167 DUF1764 PF08576.5 EGC32316.1 - 4.1 8.2 16.7 6.8 7.5 0.5 3.7 3 0 0 3 3 3 0 Eukaryotic protein of unknown function (DUF1764) Zip PF02535.17 EGC32316.1 - 4.4 6.2 5.6 7.2 5.5 3.9 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter EF-hand_1 PF00036.27 EGC32317.1 - 2.1e-13 48.4 2.4 0.00066 18.8 0.0 3.6 4 0 0 4 4 4 3 EF hand EF-hand_7 PF13499.1 EGC32317.1 - 1.3e-12 47.6 1.9 4.8e-07 29.8 0.3 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC32317.1 - 1.8e-12 46.0 1.2 0.0059 16.3 0.1 3.8 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EGC32317.1 - 8.4e-08 31.2 0.3 0.36 10.2 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_8 PF13833.1 EGC32317.1 - 2.1e-06 27.2 0.2 0.9 9.2 0.0 3.3 3 0 0 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC32317.1 - 0.0015 18.4 4.9 0.48 10.4 1.2 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC32317.1 - 0.027 14.1 0.7 2.3 7.9 0.1 2.6 2 0 0 2 2 2 0 EF hand Sigma70_r1_1 PF03979.9 EGC32317.1 - 0.21 11.5 1.4 0.82 9.6 0.0 2.5 3 1 0 3 3 3 0 Sigma-70 factor, region 1.1 DAO PF01266.19 EGC32319.1 - 3.6e-36 124.8 0.0 4.3e-36 124.5 0.0 1.1 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGC32319.1 - 0.09 12.8 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox PF00070.22 EGC32319.1 - 0.1 13.0 0.1 36 4.8 0.0 2.9 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGC32319.1 - 0.19 10.5 0.0 0.26 10.1 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain DEK_C PF08766.6 EGC32319.1 - 0.46 10.2 4.9 0.2 11.4 0.4 2.4 2 0 0 2 2 2 0 DEK C terminal domain Lectin_legB PF00139.14 EGC32321.1 - 5.7e-23 81.5 0.2 1e-22 80.6 0.1 1.4 1 0 0 1 1 1 1 Legume lectin domain Transglut_core PF01841.14 EGC32321.1 - 1.3e-13 51.1 0.1 1.3e-12 47.9 0.0 2.2 2 0 0 2 2 2 1 Transglutaminase-like superfamily Lectin_leg-like PF03388.8 EGC32321.1 - 1.6e-07 30.7 1.0 4.1e-07 29.3 0.2 2.1 2 0 0 2 2 2 1 Legume-like lectin family Rad4 PF03835.10 EGC32321.1 - 0.00029 20.2 0.0 0.00057 19.3 0.0 1.4 1 0 0 1 1 1 1 Rad4 transglutaminase-like domain Indigoidine_A PF04227.7 EGC32322.1 - 1.4e-121 405.2 0.4 2.3e-121 404.5 0.3 1.3 1 0 0 1 1 1 1 Indigoidine synthase A like protein PfkB PF00294.19 EGC32322.1 - 3.8e-34 118.1 0.0 4.3e-33 114.7 0.0 2.6 3 0 0 3 3 3 1 pfkB family carbohydrate kinase Transferase PF02458.10 EGC32323.1 - 1.5e-11 43.4 0.0 2.1e-11 42.9 0.0 1.2 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC32323.1 - 0.0035 16.2 0.0 0.035 12.9 0.0 2.2 2 1 0 2 2 2 1 Condensation domain Pkinase PF00069.20 EGC32324.1 - 1e-60 205.0 0.0 1.4e-60 204.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32324.1 - 2.2e-41 141.6 0.0 3e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC32324.1 - 4.1e-06 25.9 0.0 7.6e-06 25.0 0.0 1.3 1 0 0 1 1 1 1 Kinase-like PT-HINT PF07591.6 EGC32324.1 - 0.057 13.3 0.2 6.3 6.6 0.1 2.6 2 1 0 2 2 2 0 Pretoxin HINT domain Seadorna_VP7 PF07387.6 EGC32324.1 - 0.06 12.1 0.0 0.097 11.4 0.0 1.2 1 0 0 1 1 1 0 Seadornavirus VP7 APH PF01636.18 EGC32324.1 - 0.096 12.4 0.0 0.45 10.2 0.0 1.9 1 1 0 2 2 2 0 Phosphotransferase enzyme family TRAM_LAG1_CLN8 PF03798.11 EGC32325.1 - 1.2e-10 41.2 9.4 1.5e-10 41.0 6.5 1.1 1 0 0 1 1 1 1 TLC domain TRAM_LAG1_CLN8 PF03798.11 EGC32326.1 - 3.7e-35 121.2 33.9 3.7e-35 121.2 23.5 2.0 2 0 0 2 2 2 2 TLC domain Kei1 PF08552.6 EGC32326.1 - 0.00015 21.4 1.3 0.00018 21.2 0.1 1.7 2 0 0 2 2 2 1 Inositolphosphorylceramide synthase subunit Kei1 TRAM1 PF08390.6 EGC32326.1 - 0.041 13.3 0.4 0.041 13.3 0.3 2.9 2 0 0 2 2 2 0 TRAM1-like protein LRR_6 PF13516.1 EGC32327.1 - 4.8e-16 56.9 19.1 0.0036 17.2 0.0 8.0 8 0 0 8 8 8 3 Leucine Rich repeat Ras PF00071.17 EGC32327.1 - 1.4e-12 47.3 0.1 1.4e-12 47.3 0.0 2.3 2 0 0 2 2 2 1 Ras family LRR_4 PF12799.2 EGC32327.1 - 2.4e-07 30.2 8.3 0.021 14.4 0.0 4.8 4 1 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC32327.1 - 6.5e-06 25.4 7.4 6.3 7.2 0.1 6.7 6 0 0 6 6 6 1 Leucine Rich Repeat Miro PF08477.8 EGC32327.1 - 0.00025 21.5 1.5 0.0006 20.3 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein ARGLU PF15346.1 EGC32327.1 - 0.51 10.0 32.3 0.87 9.3 22.4 1.2 1 0 0 1 1 1 0 Arginine and glutamate-rich 1 LRR_8 PF13855.1 EGC32327.1 - 0.72 9.6 16.5 2.3 8.0 0.6 5.0 3 1 2 5 5 5 0 Leucine rich repeat TnpV PF14198.1 EGC32327.1 - 0.91 9.4 11.8 0.72 9.7 3.2 2.6 1 1 1 2 2 2 0 Transposon-encoded protein TnpV LRR_7 PF13504.1 EGC32327.1 - 1 9.8 8.1 1.2e+02 3.5 0.0 6.1 7 0 0 7 7 7 0 Leucine rich repeat UXS1_N PF11803.3 EGC32327.1 - 1.2 8.9 7.5 0.52 10.1 2.5 2.4 1 1 1 2 2 2 0 UDP-glucuronate decarboxylase N-terminal Protocadherin PF08374.6 EGC32329.1 - 0.11 12.0 3.4 0.55 9.8 0.0 2.8 3 0 0 3 3 3 0 Protocadherin Daxx PF03344.10 EGC32329.1 - 0.87 7.9 3.9 1.1 7.6 2.7 1.0 1 0 0 1 1 1 0 Daxx Family Maf PF02545.9 EGC32330.1 - 4.9e-32 110.6 0.1 5.4e-32 110.4 0.1 1.0 1 0 0 1 1 1 1 Maf-like protein Med25_VWA PF11265.3 EGC32330.1 - 0.021 13.8 0.0 0.065 12.2 0.0 1.7 2 0 0 2 2 2 0 Mediator complex subunit 25 von Willebrand factor type A CmcI PF04989.7 EGC32330.1 - 0.055 12.7 0.0 0.075 12.3 0.0 1.2 1 0 0 1 1 1 0 Cephalosporin hydroxylase Metallophos PF00149.23 EGC32331.1 - 1.5e-14 53.8 3.0 3.1e-14 52.8 2.1 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGC32331.1 - 4.6e-14 52.2 0.4 1.9e-13 50.2 0.3 2.2 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EGC32331.1 - 0.0035 15.9 0.1 0.29 9.6 0.2 2.4 2 0 0 2 2 2 2 PhoD-like phosphatase HxlR PF01638.12 EGC32331.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 HxlR-like helix-turn-helix DUF3430 PF11912.3 EGC32332.1 - 0.0041 16.9 15.5 0.0053 16.6 10.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Pkinase PF00069.20 EGC32336.1 - 5.7e-74 248.5 0.0 6.9e-74 248.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32336.1 - 1.8e-34 118.9 0.0 2.7e-34 118.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGC32336.1 - 3e-15 56.0 0.2 8.5e-15 54.6 0.1 1.8 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGC32336.1 - 9.1e-07 28.1 0.0 1.4e-06 27.5 0.0 1.4 1 1 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC32336.1 - 0.00016 20.8 0.1 0.00025 20.1 0.1 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Pox_ser-thr_kin PF05445.6 EGC32336.1 - 0.0036 16.1 2.6 0.0049 15.7 1.8 1.2 1 0 0 1 1 1 1 Poxvirus serine/threonine protein kinase RIO1 PF01163.17 EGC32336.1 - 0.022 14.1 0.1 0.035 13.4 0.1 1.2 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGC32336.1 - 0.064 12.9 0.0 0.43 10.2 0.0 2.0 2 0 0 2 2 2 0 Phosphotransferase enzyme family WD40 PF00400.27 EGC32337.1 - 1.1e-39 132.9 12.3 7.6e-10 38.2 0.9 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGC32337.1 - 4.1e-06 26.6 2.6 0.00048 19.8 0.2 3.2 1 1 2 3 3 3 2 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGC32337.1 - 0.00022 19.5 1.0 0.25 9.4 0.0 2.5 1 1 1 2 2 2 2 Nucleoporin Nup120/160 IKI3 PF04762.7 EGC32337.1 - 0.00041 18.3 0.7 0.44 8.2 0.1 2.5 2 1 0 2 2 2 2 IKI3 family Gmad1 PF10647.4 EGC32337.1 - 0.021 14.2 0.1 0.2 11.0 0.1 2.2 2 0 0 2 2 2 0 Lipoprotein LpqB beta-propeller domain TFIIIC_delta PF12657.2 EGC32337.1 - 0.056 13.1 4.3 1.6 8.4 0.1 3.6 1 1 2 3 3 3 0 Transcription factor IIIC subunit delta N-term VCBS PF13517.1 EGC32339.1 - 1.5e-18 66.9 25.7 7.4e-07 29.4 4.0 5.8 4 3 2 6 6 6 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGC32339.1 - 7.2e-10 38.2 18.3 0.054 13.2 0.4 7.1 7 0 0 7 7 7 6 FG-GAP repeat NUDIX PF00293.23 EGC32340.1 - 5.1e-14 52.0 0.0 8.2e-14 51.3 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Ribosomal_S17 PF00366.15 EGC32341.1 - 1.2e-28 98.8 1.0 1.9e-28 98.2 0.7 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 Ribosomal_S8e PF01201.17 EGC32342.1 - 3.7e-48 163.0 3.7 4.8e-48 162.6 2.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S8e TPR_11 PF13414.1 EGC32344.1 - 1.2e-34 117.8 12.3 7e-17 60.8 0.1 5.3 3 2 1 5 5 5 5 TPR repeat TPR_2 PF07719.12 EGC32344.1 - 1e-26 90.6 6.8 0.00023 20.8 0.1 7.0 7 0 0 7 7 7 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32344.1 - 3.8e-21 73.7 11.6 6.3e-06 25.5 0.3 6.3 6 0 0 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32344.1 - 1.8e-12 47.5 0.2 0.0004 20.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC32344.1 - 5.2e-11 42.2 0.0 2.6e-07 30.4 0.0 3.5 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32344.1 - 8.1e-11 40.9 18.7 0.02 14.6 0.3 6.1 3 1 2 5 5 5 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32344.1 - 1.6e-10 40.3 0.8 4.7e-05 23.2 0.0 5.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32344.1 - 9.3e-10 38.3 3.0 0.0077 16.1 0.0 4.6 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC32344.1 - 2.7e-08 33.7 0.0 0.29 11.8 0.0 4.7 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32344.1 - 3.2e-07 30.5 0.2 0.0011 19.2 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32344.1 - 0.00013 21.4 0.7 0.9 9.4 0.0 4.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32344.1 - 0.11 13.0 7.5 20 5.9 0.0 5.0 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1724 PF08350.5 EGC32345.1 - 0.075 12.5 0.3 1.4 8.4 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1724) Frataxin_Cyay PF01491.11 EGC32345.1 - 0.24 11.2 1.2 0.32 10.8 0.1 1.7 2 0 0 2 2 2 0 Frataxin-like domain LIM PF00412.17 EGC32346.1 - 5.4e-39 132.0 64.7 2.6e-11 43.4 2.7 5.6 5 0 0 5 5 5 5 LIM domain PTEN_C2 PF10409.4 EGC32346.1 - 4.1e-13 49.2 0.2 1.2e-12 47.6 0.1 1.8 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 EGC32346.1 - 2.1e-07 30.5 0.9 5.5e-07 29.2 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC32346.1 - 3.1e-07 29.9 0.2 8.4e-07 28.5 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC32346.1 - 0.00098 19.4 0.0 0.0024 18.1 0.0 1.6 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGC32346.1 - 0.0034 17.4 0.0 0.0077 16.2 0.0 1.6 1 0 0 1 1 1 1 Inositol hexakisphosphate DSPn PF14671.1 EGC32346.1 - 0.011 15.7 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 Dual specificity protein phosphatase, N-terminal half MRP_L53 PF10780.4 EGC32347.1 - 0.057 13.4 0.6 0.14 12.1 0.4 1.8 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 DASH_Dad4 PF08650.5 EGC32347.1 - 0.22 11.4 1.2 1.2 9.1 0.1 2.2 1 1 1 2 2 2 0 DASH complex subunit Dad4 Coiled PF05710.7 EGC32348.1 - 0.17 12.3 7.1 0.24 11.8 4.9 1.2 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC32349.1 - 0.017 15.5 9.9 0.02 15.3 6.9 1.1 1 0 0 1 1 1 0 Coiled coil DUF2672 PF10878.3 EGC32353.1 - 0.14 11.9 0.1 0.29 10.8 0.1 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2672) DUF2057 PF09829.4 EGC32354.1 - 0.0015 18.2 0.0 3 7.4 0.0 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2057) Cadherin-like PF12733.2 EGC32354.1 - 0.0017 18.5 1.7 6 7.2 0.1 4.1 4 0 0 4 4 4 2 Cadherin-like beta sandwich domain FolB PF02152.13 EGC32357.1 - 0.027 14.6 0.0 0.06 13.5 0.0 1.5 1 0 0 1 1 1 0 Dihydroneopterin aldolase C1-set PF07654.10 EGC32357.1 - 1.3 9.0 5.6 1.4 8.9 0.3 2.3 1 1 1 2 2 2 0 Immunoglobulin C1-set domain Macoilin PF09726.4 EGC32357.1 - 1.7 6.8 18.2 1.8 6.7 12.6 1.1 1 0 0 1 1 1 0 Transmembrane protein BolA PF01722.13 EGC32358.1 - 0.063 13.2 0.0 0.12 12.3 0.0 1.5 1 0 0 1 1 1 0 BolA-like protein zf-C3HC4_3 PF13920.1 EGC32359.1 - 8.4e-07 28.5 4.8 1.3e-06 27.9 3.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32359.1 - 1.3e-05 25.0 10.4 0.00025 20.9 7.4 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC32359.1 - 3.3e-05 23.4 10.5 0.00027 20.5 7.2 2.2 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32359.1 - 0.00013 21.5 9.6 0.00084 19.0 6.7 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC32359.1 - 0.00014 21.9 2.7 0.0002 21.4 1.9 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGC32359.1 - 0.00017 21.3 9.0 0.0006 19.5 6.2 1.8 1 1 0 1 1 1 1 Ring finger domain zf-Apc11 PF12861.2 EGC32359.1 - 0.00079 19.2 1.2 0.0011 18.7 0.8 1.3 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC32359.1 - 0.0019 18.0 4.9 0.0019 18.0 3.4 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC32359.1 - 0.033 13.7 8.0 0.12 11.9 5.7 1.8 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Rad50_zn_hook PF04423.9 EGC32359.1 - 0.035 13.5 0.1 0.035 13.5 0.1 2.3 2 1 0 2 2 2 0 Rad50 zinc hook motif NTR PF01759.16 EGC32359.1 - 0.074 12.6 0.4 0.11 12.1 0.3 1.2 1 0 0 1 1 1 0 UNC-6/NTR/C345C module zf-RING_3 PF14369.1 EGC32359.1 - 0.09 12.7 5.3 0.15 12.0 1.4 2.5 2 0 0 2 2 2 0 zinc-finger Prok-RING_4 PF14447.1 EGC32359.1 - 0.14 11.7 4.7 0.32 10.5 3.3 1.6 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 FYVE PF01363.16 EGC32359.1 - 0.32 10.9 5.5 8.5 6.3 0.5 3.1 2 1 1 3 3 3 0 FYVE zinc finger zf-RING_6 PF14835.1 EGC32359.1 - 0.39 10.5 6.2 6.5 6.6 4.4 2.2 1 1 1 2 2 2 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC32359.1 - 1.2 8.9 4.8 0.75 9.5 1.0 2.4 1 1 1 2 2 2 0 RING-type zinc-finger DZR PF12773.2 EGC32359.1 - 2.6 7.9 7.2 97 2.8 5.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon FLO_LFY PF01698.11 EGC32360.1 - 0.22 10.3 12.0 0.25 10.1 8.3 1.0 1 0 0 1 1 1 0 Floricaula / Leafy protein DDHD PF02862.12 EGC32360.1 - 0.4 10.4 11.5 0.46 10.2 8.0 1.0 1 0 0 1 1 1 0 DDHD domain DUF1509 PF07420.6 EGC32360.1 - 0.46 9.7 7.6 0.46 9.7 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) Nucleo_P87 PF07267.6 EGC32360.1 - 2 7.0 12.4 2.2 6.8 8.6 1.0 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Hox9_act PF04617.8 EGC32360.1 - 3.8 7.6 7.3 5 7.2 5.1 1.3 1 1 0 1 1 1 0 Hox9 activation region IL4 PF00727.13 EGC32361.1 - 0.98 9.3 6.1 6 6.7 0.1 2.9 3 0 0 3 3 3 0 Interleukin 4 MRP-L46 PF11788.3 EGC32362.1 - 2.3e-07 31.4 1.6 2.3e-07 31.4 1.1 2.7 2 1 0 2 2 2 1 39S mitochondrial ribosomal protein L46 NUDIX PF00293.23 EGC32362.1 - 0.00021 20.9 0.0 0.00041 19.9 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Na_H_Exchanger PF00999.16 EGC32363.1 - 1.6e-71 240.8 42.5 2e-71 240.5 29.4 1.1 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family Asp-Al_Ex PF06826.7 EGC32363.1 - 3.6e-05 23.3 6.1 3.6e-05 23.3 4.2 3.1 2 2 2 4 4 4 1 Predicted Permease Membrane Region Endotoxin_N PF03945.9 EGC32364.1 - 1.5e-05 24.5 0.2 0.0034 16.8 0.1 2.4 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain Endotoxin_N PF03945.9 EGC32365.1 - 0.0006 19.2 1.4 0.048 13.0 0.1 2.2 1 1 1 2 2 2 2 delta endotoxin, N-terminal domain RhoGAP PF00620.22 EGC32366.1 - 7.8e-19 67.7 0.0 2.2e-18 66.3 0.0 1.8 1 0 0 1 1 1 1 RhoGAP domain FCH PF00611.18 EGC32366.1 - 2.6e-15 56.3 1.0 2.6e-15 56.3 0.7 3.3 3 0 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain HCaRG PF07258.9 EGC32367.1 - 6.3e-34 117.0 4.2 7.2e-34 116.8 2.9 1.0 1 0 0 1 1 1 1 HCaRG protein HTH_Tnp_ISL3 PF13542.1 EGC32367.1 - 0.12 11.6 0.0 0.29 10.3 0.0 1.7 1 1 1 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 Ded_cyto PF06920.8 EGC32368.1 - 4.1e-30 104.3 1.2 4.1e-30 104.3 0.9 2.8 3 0 0 3 3 3 1 Dedicator of cytokinesis F-box-like PF12937.2 EGC32368.1 - 1.8e-07 30.7 1.7 4.7e-07 29.4 1.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC32368.1 - 0.00055 19.5 0.5 0.0019 17.7 0.4 2.0 1 0 0 1 1 1 1 F-box domain COX6B PF02297.12 EGC32369.1 - 0.1 12.6 4.5 11 6.0 3.1 2.4 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb Pet191_N PF10203.4 EGC32369.1 - 0.16 12.0 4.8 0.05 13.6 1.3 1.7 2 0 0 2 2 2 0 Cytochrome c oxidase assembly protein PET191 Cmc1 PF08583.5 EGC32369.1 - 0.59 9.9 5.7 0.92 9.3 0.2 2.8 1 1 1 2 2 2 0 Cytochrome c oxidase biogenesis protein Cmc1 like Rad10 PF03834.9 EGC32370.1 - 1.2e-17 63.3 1.3 3.1e-17 62.0 0.2 2.0 2 0 0 2 2 2 1 Binding domain of DNA repair protein Ercc1 (rad10/Swi10) HHH_5 PF14520.1 EGC32370.1 - 2.9e-07 30.5 0.0 5.4e-07 29.6 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix domain HHH_2 PF12826.2 EGC32370.1 - 3.2e-06 26.9 0.0 4.9e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH PF00633.18 EGC32370.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 1 0 0 1 1 1 0 Helix-hairpin-helix motif VWA_2 PF13519.1 EGC32371.1 - 3.4e-12 46.8 0.0 9.9e-12 45.2 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD PF11976.3 EGC32371.1 - 3.5e-09 36.2 0.6 2e-08 33.7 0.0 2.7 3 1 0 3 3 3 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGC32371.1 - 7.5e-09 34.8 2.2 1.5e-07 30.7 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin family Ras PF00071.17 EGC32371.1 - 5.8e-05 22.5 0.1 0.00019 20.8 0.0 1.9 1 0 0 1 1 1 1 Ras family Mucin PF01456.12 EGC32371.1 - 0.11 12.3 9.8 0.03 14.0 2.8 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein CBS PF00571.23 EGC32372.1 - 6.9e-26 89.7 1.0 4.9e-08 32.6 0.0 3.2 3 0 0 3 3 3 3 CBS domain ACBP PF00887.14 EGC32373.1 - 1.4e-29 101.5 0.2 3.3e-29 100.3 0.1 1.6 1 0 0 1 1 1 1 Acyl CoA binding protein Ank_5 PF13857.1 EGC32373.1 - 2.7e-21 75.1 0.0 5.1e-12 45.6 0.0 2.3 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC32373.1 - 6.7e-18 64.8 0.0 1.3e-17 63.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC32373.1 - 2.1e-17 61.9 0.1 1.1e-08 34.4 0.0 2.6 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGC32373.1 - 2.5e-16 59.7 0.0 5.6e-11 42.6 0.0 2.9 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32373.1 - 3.3e-13 48.4 0.0 4.9e-07 29.3 0.0 2.7 2 0 0 2 2 2 2 Ankyrin repeat Ribosomal_S6 PF01250.12 EGC32373.1 - 0.0079 16.0 0.6 0.65 9.8 0.1 3.0 2 1 1 3 3 3 1 Ribosomal protein S6 GvpL_GvpF PF06386.6 EGC32373.1 - 0.5 9.8 4.7 1.1 8.8 3.3 1.5 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF Taxilin PF09728.4 EGC32374.1 - 8.6e-44 149.8 62.3 8.6e-44 149.8 43.2 2.1 1 1 1 2 2 2 1 Myosin-like coiled-coil protein TMF_DNA_bd PF12329.3 EGC32374.1 - 0.0004 20.1 33.3 0.0016 18.2 9.2 7.7 5 2 4 9 9 9 2 TATA element modulatory factor 1 DNA binding DUF4200 PF13863.1 EGC32374.1 - 0.0032 17.4 15.0 0.0032 17.4 10.4 6.2 2 1 2 5 5 5 2 Domain of unknown function (DUF4200) Reo_sigmaC PF04582.7 EGC32374.1 - 1.2 8.2 19.0 0.049 12.7 3.6 2.9 1 1 2 4 4 4 0 Reovirus sigma C capsid protein UPF0242 PF06785.6 EGC32374.1 - 3.1 6.3 41.5 0.92 8.1 8.8 2.7 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0242) DIT1_PvcA PF05141.7 EGC32374.1 - 9.8 5.3 33.3 0.41 9.8 3.1 3.6 2 2 1 3 3 3 0 Pyoverdine/dityrosine biosynthesis protein Alg6_Alg8 PF03155.10 EGC32375.1 - 1.2e-130 436.4 41.1 1.6e-130 436.1 28.5 1.1 1 0 0 1 1 1 1 ALG6, ALG8 glycosyltransferase family RWD PF05773.17 EGC32376.1 - 8.1e-11 41.8 0.2 8.1e-11 41.8 0.2 2.2 2 0 0 2 2 2 1 RWD domain zf-RING_5 PF14634.1 EGC32376.1 - 0.00014 21.5 6.5 0.00014 21.5 4.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC32376.1 - 0.00014 21.6 4.7 0.00014 21.6 3.2 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC32376.1 - 0.00087 18.9 3.0 0.00087 18.9 2.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32376.1 - 0.0022 17.9 5.1 0.0022 17.9 3.5 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DZR PF12773.2 EGC32376.1 - 0.024 14.4 9.5 0.92 9.3 0.6 3.5 2 1 1 3 3 3 0 Double zinc ribbon Nudix_N_2 PF14803.1 EGC32376.1 - 0.027 14.1 6.8 0.036 13.7 0.1 3.2 3 0 0 3 3 3 0 Nudix N-terminal zf-ribbon_3 PF13248.1 EGC32376.1 - 0.034 13.3 0.5 0.034 13.3 0.3 2.7 3 0 0 3 3 3 0 zinc-ribbon domain zf-CHY PF05495.7 EGC32376.1 - 0.096 12.8 9.8 0.13 12.4 5.6 2.1 1 1 1 2 2 2 0 CHY zinc finger Ecl1 PF12855.2 EGC32376.1 - 0.34 10.2 8.7 0.71 9.2 0.8 3.5 3 0 0 3 3 3 0 Life-span regulatory factor zf-C3HC4 PF00097.20 EGC32376.1 - 2.4 7.8 16.7 0.025 14.2 4.6 2.7 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC32376.1 - 5 7.0 10.2 0.21 11.4 2.0 2.5 2 1 0 2 2 2 0 zinc finger of C3HC4-type, RING DUF1033 PF06279.6 EGC32376.1 - 6.9 6.5 9.3 1.8 8.3 1.6 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1033) p450 PF00067.17 EGC32377.1 - 2e-80 270.6 0.1 2.2e-80 270.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Cullin PF00888.17 EGC32378.1 - 2.2e-174 581.3 36.3 2.2e-174 581.3 25.1 1.4 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGC32378.1 - 8.5e-28 95.9 2.7 8.5e-28 95.9 1.9 3.3 3 0 0 3 3 3 1 Cullin protein neddylation domain MarR PF01047.17 EGC32378.1 - 0.0034 17.0 0.2 2.3 7.9 0.1 2.6 2 0 0 2 2 2 2 MarR family HTH_27 PF13463.1 EGC32378.1 - 0.0071 16.6 0.0 0.35 11.2 0.0 2.5 2 0 0 2 2 2 1 Winged helix DNA-binding domain Rio2_N PF09202.6 EGC32378.1 - 0.046 13.8 1.9 0.21 11.7 0.0 3.0 4 0 0 4 4 4 0 Rio2, N-terminal Rrf2 PF02082.15 EGC32378.1 - 0.097 12.8 0.0 1.1 9.3 0.0 2.6 3 0 0 3 3 3 0 Transcriptional regulator ThiF PF00899.16 EGC32379.1 - 1.4e-35 122.0 0.8 2.6e-35 121.1 0.0 1.9 2 0 0 2 2 2 1 ThiF family Saccharop_dh PF03435.13 EGC32379.1 - 0.012 14.6 0.1 0.024 13.6 0.1 1.4 1 1 0 1 1 1 0 Saccharopine dehydrogenase NAD_binding_7 PF13241.1 EGC32379.1 - 0.012 15.8 0.0 0.028 14.6 0.0 1.5 1 0 0 1 1 1 0 Putative NAD(P)-binding ApbA PF02558.11 EGC32379.1 - 0.051 13.0 0.0 0.22 10.9 0.0 2.1 3 0 0 3 3 3 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGC32379.1 - 0.081 13.0 0.6 0.32 11.0 0.3 2.0 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGC32379.1 - 0.12 11.9 0.0 1 8.9 0.0 2.1 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain RNA_POL_M_15KD PF02150.11 EGC32380.1 - 2.8e-12 46.0 3.3 2.8e-12 46.0 2.3 2.7 2 1 1 3 3 3 1 RNA polymerases M/15 Kd subunit TFIIS_C PF01096.13 EGC32380.1 - 6.7e-11 41.6 3.8 6.7e-11 41.6 2.6 3.0 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) Lar_restr_allev PF14354.1 EGC32380.1 - 0.037 14.3 1.4 0.037 14.3 1.0 2.7 2 1 0 2 2 2 0 Restriction alleviation protein Lar TF_Zn_Ribbon PF08271.7 EGC32380.1 - 0.054 12.8 1.2 0.054 12.8 0.9 2.9 3 0 0 3 3 3 0 TFIIB zinc-binding zinc_ribbon_2 PF13240.1 EGC32380.1 - 0.098 12.1 4.2 2.8 7.5 0.2 2.6 2 0 0 2 2 2 0 zinc-ribbon domain Zn_Tnp_IS1595 PF12760.2 EGC32380.1 - 0.12 12.1 9.2 0.14 11.9 1.6 2.6 2 1 0 2 2 2 0 Transposase zinc-ribbon domain zf-ribbon_3 PF13248.1 EGC32380.1 - 0.12 11.5 5.5 0.8 8.9 0.0 2.9 3 0 0 3 3 3 0 zinc-ribbon domain zf-RING_3 PF14369.1 EGC32380.1 - 0.27 11.2 7.7 1.5 8.8 0.1 3.0 3 0 0 3 3 3 0 zinc-finger zf-GRF PF06839.7 EGC32380.1 - 0.77 9.7 5.9 0.3 11.0 1.3 2.1 2 0 0 2 2 2 0 GRF zinc finger Antiterm PF03589.8 EGC32380.1 - 1.2 9.2 5.1 1.6 8.8 0.5 2.1 2 0 0 2 2 2 0 Antitermination protein DZR PF12773.2 EGC32380.1 - 5.1 7.0 15.5 1.6e+03 -1.1 10.7 2.9 1 1 0 1 1 1 0 Double zinc ribbon Zn_ribbon_recom PF13408.1 EGC32380.1 - 5.8 7.2 9.9 4.6 7.5 1.6 2.3 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2387 PF09526.5 EGC32380.1 - 6.6 6.7 10.0 5.8 6.9 1.3 2.3 2 0 0 2 2 2 0 Probable metal-binding protein (DUF2387) FF PF01846.14 EGC32381.1 - 0.00047 20.0 4.8 0.27 11.2 0.1 4.1 3 0 0 3 3 3 2 FF domain BUD22 PF09073.5 EGC32381.1 - 0.25 10.3 7.7 0.29 10.1 2.9 2.2 1 1 1 2 2 2 0 BUD22 Peptidase_M22 PF00814.20 EGC32384.1 - 3.8e-72 242.9 0.0 5.1e-72 242.5 0.0 1.2 1 0 0 1 1 1 1 Glycoprotease family YycC PF14174.1 EGC32384.1 - 0.00033 20.2 0.0 0.00085 18.9 0.0 1.7 1 0 0 1 1 1 1 YycC-like protein FGGY_C PF02782.11 EGC32384.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain COesterase PF00135.23 EGC32385.1 - 9.5e-130 433.8 0.0 1.2e-129 433.4 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC32385.1 - 1.5e-06 27.9 0.1 1.1e-05 25.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Imm13 PF15564.1 EGC32385.1 - 0.004 16.8 0.2 0.011 15.4 0.0 1.7 2 0 0 2 2 2 1 Immunity protein 13 Peptidase_S9 PF00326.16 EGC32385.1 - 0.005 16.0 0.0 0.0086 15.3 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family UCH PF00443.24 EGC32386.1 - 4e-51 173.7 0.2 6.3e-51 173.0 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC32386.1 - 1.1e-18 67.7 0.8 6.3e-18 65.2 0.5 2.2 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UBA PF00627.26 EGC32386.1 - 4.9e-17 61.2 0.1 6.1e-09 35.4 0.0 2.5 2 0 0 2 2 2 2 UBA/TS-N domain zf-UBP PF02148.14 EGC32386.1 - 1.7e-16 60.0 0.9 4.8e-15 55.4 0.0 2.5 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Response_reg PF00072.19 EGC32387.1 - 1.3e-20 73.4 0.4 2.5e-20 72.5 0.2 1.4 1 0 0 1 1 1 1 Response regulator receiver domain LRR_6 PF13516.1 EGC32387.1 - 7.1e-16 56.4 37.1 0.13 12.3 0.1 11.0 10 1 0 10 10 10 8 Leucine Rich repeat LRR_8 PF13855.1 EGC32387.1 - 7.3e-09 35.2 23.7 0.00025 20.7 2.5 5.2 3 2 1 4 4 4 3 Leucine rich repeat Glyoxalase_2 PF12681.2 EGC32389.1 - 2.6e-09 37.6 0.0 3.1e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase PF00903.20 EGC32389.1 - 3.1e-08 33.6 0.0 1.7e-07 31.2 0.0 1.9 1 1 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EGC32389.1 - 0.0012 18.5 0.2 0.084 12.5 0.0 2.1 2 0 0 2 2 2 2 CppA N-terminal Glyoxalase_3 PF13468.1 EGC32389.1 - 0.16 11.8 0.0 0.21 11.4 0.0 1.4 1 1 0 1 1 1 0 Glyoxalase-like domain DUF605 PF04652.11 EGC32390.1 - 0.0069 15.8 7.0 0.0069 15.8 4.9 1.4 2 0 0 2 2 2 1 Vta1 like NUDE_C PF04880.8 EGC32390.1 - 1 9.6 19.4 0.079 13.3 10.1 1.6 2 0 0 2 2 2 0 NUDE protein, C-terminal conserved region TPR_11 PF13414.1 EGC32391.1 - 2.7e-19 68.5 11.5 5.3e-14 51.6 3.0 3.4 2 1 1 3 3 3 2 TPR repeat TPR_1 PF00515.23 EGC32391.1 - 2.8e-13 48.8 10.5 5.3e-05 22.6 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32391.1 - 8.4e-09 34.6 8.0 0.0081 16.0 0.0 4.4 4 1 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC32391.1 - 3.3e-05 24.1 0.0 0.063 13.9 0.0 3.2 1 1 2 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC32391.1 - 4.9e-05 23.3 1.8 4.9e-05 23.3 1.3 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGC32391.1 - 0.0001 22.1 3.3 0.0038 17.1 0.6 3.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32391.1 - 0.0002 20.8 1.3 0.11 12.2 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32391.1 - 0.0005 20.3 0.2 0.03 14.6 0.1 2.8 2 1 0 2 2 1 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32391.1 - 0.0008 20.0 0.0 0.3 11.8 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32391.1 - 0.0011 18.6 2.0 1.9 8.4 0.2 3.8 2 1 1 3 3 3 1 Tetratricopeptide repeat RPN7 PF10602.4 EGC32391.1 - 0.047 13.0 0.5 0.047 13.0 0.3 2.4 2 0 0 2 2 2 0 26S proteasome subunit RPN7 Fis1_TPR_C PF14853.1 EGC32391.1 - 0.068 13.0 0.7 1.2 9.0 0.0 2.8 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EGC32391.1 - 0.097 12.9 0.0 0.097 12.9 0.0 4.5 6 0 0 6 6 4 0 Tetratricopeptide repeat DUF342 PF03961.8 EGC32391.1 - 0.34 9.2 8.8 0.43 8.9 2.9 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF342) MIT PF04212.13 EGC32391.1 - 0.48 10.3 7.9 5.2 7.0 0.2 3.3 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain OmpH PF03938.9 EGC32391.1 - 9.4 6.1 10.6 1.4 8.8 2.4 2.2 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Rad60-SLD PF11976.3 EGC32393.1 - 1.1e-23 82.7 0.1 1.3e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGC32393.1 - 2.8e-10 39.4 0.1 3.5e-10 39.1 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family RE_TdeIII PF09520.5 EGC32393.1 - 0.049 12.9 0.1 0.058 12.6 0.0 1.2 1 0 0 1 1 1 0 Type II restriction endonuclease, TdeIII FYVE PF01363.16 EGC32394.1 - 2.2e-21 75.5 14.3 2.6e-21 75.2 9.9 1.1 1 0 0 1 1 1 1 FYVE zinc finger FYVE_2 PF02318.11 EGC32394.1 - 0.11 12.3 13.5 0.17 11.8 9.4 1.3 1 1 0 1 1 1 0 FYVE-type zinc finger HypA PF01155.14 EGC32394.1 - 0.47 10.1 11.4 0.11 12.2 5.1 1.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family DUF4637 PF15470.1 EGC32394.1 - 2 8.0 7.9 3 7.4 5.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4637) zf-SNAP50_C PF12251.3 EGC32394.1 - 7.2 5.9 14.7 5.5 6.3 3.6 2.0 1 1 1 2 2 2 0 snRNA-activating protein of 50kDa MW C terminal TMEM154 PF15102.1 EGC32395.1 - 0.00017 21.3 0.3 0.00033 20.3 0.2 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.3 EGC32395.1 - 0.042 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4448 PF14610.1 EGC32395.1 - 0.055 12.9 2.6 0.13 11.6 1.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) Methyltransf_11 PF08241.7 EGC32397.1 - 4e-19 68.9 0.0 1e-18 67.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32397.1 - 2.3e-13 50.0 0.2 6.7e-13 48.4 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC32397.1 - 2.8e-13 49.5 0.0 1.2e-12 47.4 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGC32397.1 - 5.3e-12 45.9 0.0 9.6e-12 45.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32397.1 - 1.1e-11 45.2 0.0 2.5e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC32397.1 - 2.3e-10 40.8 0.1 9e-10 38.9 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32397.1 - 2.3e-08 33.9 0.0 3.9e-08 33.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC32397.1 - 1.9e-07 31.1 0.0 3.4e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC32397.1 - 0.00018 21.1 0.0 0.00039 20.1 0.0 1.5 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EGC32397.1 - 0.018 14.3 0.0 0.032 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain FmrO PF07091.6 EGC32397.1 - 0.092 11.7 0.0 0.14 11.1 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Keratin_assoc PF09775.4 EGC32398.1 - 1.7e-17 63.2 2.9 2.1e-17 62.8 2.0 1.1 1 0 0 1 1 1 1 Keratinocyte-associated protein 2 PIG-F PF06699.6 EGC32398.1 - 0.065 13.1 2.9 0.078 12.9 1.6 1.4 1 1 0 1 1 1 0 GPI biosynthesis protein family Pig-F Ycf1 PF05758.7 EGC32398.1 - 0.17 9.5 1.6 0.19 9.3 1.1 1.0 1 0 0 1 1 1 0 Ycf1 DUF3169 PF11368.3 EGC32398.1 - 0.68 9.0 6.2 0.21 10.7 2.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3169) DUF4120 PF13496.1 EGC32399.1 - 0.0069 16.3 0.3 0.013 15.4 0.2 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4120) TPR_11 PF13414.1 EGC32401.1 - 2.2e-39 132.9 16.6 1.1e-10 41.0 1.2 6.6 3 2 3 7 7 7 7 TPR repeat TPR_1 PF00515.23 EGC32401.1 - 2.7e-33 112.2 27.8 5.5e-06 25.7 0.3 9.3 10 0 0 10 10 8 7 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32401.1 - 4.1e-32 107.4 13.0 6.2e-05 22.6 0.3 9.5 8 1 1 9 9 9 6 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32401.1 - 7.2e-27 93.4 0.2 2.9e-05 24.6 0.0 6.8 5 1 2 7 7 7 5 Tetratricopeptide repeat DnaJ PF00226.26 EGC32401.1 - 2.2e-23 81.7 15.3 1.3e-22 79.3 4.9 3.4 3 0 0 3 3 3 1 DnaJ domain TPR_8 PF13181.1 EGC32401.1 - 4.6e-21 72.9 31.4 5.2e-05 22.7 0.0 9.5 9 1 0 9 9 9 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGC32401.1 - 4.1e-17 61.1 0.6 0.001 19.5 0.0 7.4 5 3 2 7 7 7 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32401.1 - 3.8e-16 59.1 7.2 9.5e-05 22.6 0.1 6.5 5 2 1 6 6 6 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32401.1 - 1.7e-14 53.5 18.7 6.7e-06 25.9 0.0 7.9 3 2 5 8 8 8 5 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32401.1 - 7.2e-13 47.6 10.4 0.0022 18.0 0.0 8.2 9 1 0 9 9 8 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC32401.1 - 5.9e-11 42.0 0.0 0.00012 21.8 0.0 4.1 3 1 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC32401.1 - 1.8e-10 40.8 15.6 0.0011 19.1 0.0 5.1 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGC32401.1 - 5.2e-09 35.2 1.6 0.0091 15.7 0.0 6.6 5 2 1 6 6 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32401.1 - 1.2e-07 31.7 13.4 0.13 12.7 0.0 8.5 8 1 2 10 10 8 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGC32401.1 - 1.6e-06 28.1 6.6 0.0079 16.2 0.1 5.2 2 2 2 4 4 4 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC32401.1 - 3.2e-06 26.8 5.3 7.4 6.6 0.0 6.9 6 1 1 7 7 7 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC32401.1 - 5.3e-06 26.2 8.6 0.033 14.0 0.2 6.0 6 0 0 6 6 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_15 PF13429.1 EGC32401.1 - 5.6e-06 25.6 0.6 0.017 14.2 0.1 4.1 2 2 1 3 3 3 1 Tetratricopeptide repeat NARP1 PF12569.3 EGC32401.1 - 0.00019 20.3 7.9 0.00019 20.3 5.5 4.2 1 1 1 2 2 1 1 NMDA receptor-regulated protein 1 DUF3856 PF12968.2 EGC32401.1 - 0.0067 16.2 2.0 3.4 7.4 0.0 5.3 4 2 0 4 4 4 1 Domain of Unknown Function (DUF3856) Apc5 PF12862.2 EGC32401.1 - 0.092 12.5 1.6 22 4.9 0.0 4.0 4 1 0 4 4 4 0 Anaphase-promoting complex subunit 5 Spectrin PF00435.16 EGC32401.1 - 0.15 12.3 7.5 0.76 10.0 0.4 3.1 3 0 0 3 3 2 0 Spectrin repeat MIT PF04212.13 EGC32401.1 - 0.17 11.8 15.1 1.4 8.8 0.0 6.0 5 1 1 6 6 5 0 MIT (microtubule interacting and transport) domain Sec5 PF15469.1 EGC32401.1 - 0.45 10.2 12.8 9.1 5.9 1.4 3.7 3 1 0 3 3 3 0 Exocyst complex component Sec5 UPF0122 PF04297.9 EGC32401.1 - 6.4 6.8 11.6 0.13 12.2 0.4 3.2 2 1 1 3 3 3 0 Putative helix-turn-helix protein, YlxM / p13 like E1_dh PF00676.15 EGC32402.1 - 1.9e-91 305.9 0.6 2.2e-91 305.6 0.1 1.4 2 0 0 2 2 2 1 Dehydrogenase E1 component DXP_synthase_N PF13292.1 EGC32402.1 - 0.0023 16.9 0.0 0.013 14.4 0.0 2.2 2 0 0 2 2 2 1 1-deoxy-D-xylulose-5-phosphate synthase Amidase02_C PF12123.3 EGC32402.1 - 0.05 13.2 0.3 0.11 12.0 0.2 1.6 1 0 0 1 1 1 0 N-acetylmuramoyl-l-alanine amidase Pneumo_M2 PF07380.6 EGC32402.1 - 0.065 13.2 0.0 0.24 11.4 0.0 2.0 1 0 0 1 1 1 0 Pneumovirus M2 protein TPR_1 PF00515.23 EGC32404.1 - 4.5e-29 98.8 6.8 7.3e-08 31.6 0.3 7.5 7 0 0 7 7 7 4 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32404.1 - 4.3e-21 73.0 13.0 0.0001 21.9 0.1 9.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGC32404.1 - 6.6e-21 73.7 22.3 5e-12 45.2 0.1 7.5 9 0 0 9 9 9 3 TPR repeat TPR_12 PF13424.1 EGC32404.1 - 1.3e-20 73.1 5.5 8.5e-12 44.8 0.0 6.4 4 1 4 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC32404.1 - 3.1e-14 52.8 35.8 1.4e-08 34.7 4.2 6.3 3 2 2 6 6 6 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGC32404.1 - 5.3e-13 47.7 19.5 0.0015 18.1 0.0 8.4 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32404.1 - 4.6e-12 44.7 0.1 0.0085 15.8 0.0 4.6 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32404.1 - 3.6e-09 36.8 0.9 0.034 14.4 0.0 6.0 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32404.1 - 1.7e-08 34.8 0.0 0.0035 17.9 0.0 3.7 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGC32404.1 - 2.9e-08 33.3 0.0 0.4 10.6 0.0 3.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC32404.1 - 3.3e-08 33.4 0.0 0.51 11.1 0.0 4.9 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32404.1 - 4.1e-07 29.6 10.9 0.13 12.5 0.0 7.6 7 0 0 7 7 6 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC32404.1 - 7.6e-06 25.6 0.0 0.00018 21.2 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32404.1 - 3.9e-05 23.8 5.1 13 6.4 0.1 6.3 7 0 0 7 7 5 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC32404.1 - 0.0028 17.4 2.3 0.22 11.4 0.5 3.7 3 0 0 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_3 PF07720.7 EGC32404.1 - 0.021 14.6 0.1 0.021 14.6 0.1 4.4 5 0 0 5 5 5 0 Tetratricopeptide repeat RAMP PF04901.8 EGC32406.1 - 0.006 16.3 1.4 0.006 16.3 1.0 1.8 1 1 1 2 2 2 1 Receptor activity modifying family NicO PF03824.11 EGC32406.1 - 0.0088 15.3 9.2 0.0088 15.3 6.3 1.4 2 0 0 2 2 2 1 High-affinity nickel-transport protein YfiO PF13525.1 EGC32407.1 - 0.038 13.4 0.0 0.043 13.2 0.0 1.0 1 0 0 1 1 1 0 Outer membrane lipoprotein DsrC PF04358.8 EGC32407.1 - 0.11 12.8 0.2 0.12 12.5 0.1 1.2 1 1 0 1 1 1 0 DsrC like protein Med28 PF11594.3 EGC32407.1 - 0.11 12.7 0.4 0.12 12.6 0.2 1.2 1 0 0 1 1 1 0 Mediator complex subunit 28 Atx10homo_assoc PF09759.4 EGC32408.1 - 4.3e-36 122.7 1.7 4.3e-36 122.7 1.2 4.3 4 0 0 4 4 4 2 Spinocerebellar ataxia type 10 protein domain Ric8 PF10165.4 EGC32408.1 - 0.034 12.9 12.6 0.046 12.5 6.5 2.5 1 1 0 2 2 2 0 Guanine nucleotide exchange factor synembryn Pkinase_Tyr PF07714.12 EGC32411.1 - 6e-61 205.7 0.0 9.6e-61 205.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC32411.1 - 1.4e-57 194.7 0.0 2.7e-57 193.8 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Filamin PF00630.14 EGC32411.1 - 6.8e-07 29.8 0.0 2e-06 28.2 0.0 1.9 1 0 0 1 1 1 1 Filamin/ABP280 repeat Arm PF00514.18 EGC32411.1 - 0.022 14.5 0.2 0.78 9.6 0.0 3.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat ubiquitin PF00240.18 EGC32411.1 - 0.038 13.3 2.3 1 8.7 0.0 3.3 3 0 0 3 3 3 0 Ubiquitin family Kinase-like PF14531.1 EGC32411.1 - 0.13 11.1 0.0 0.28 10.0 0.0 1.5 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGC32411.1 - 0.14 11.8 0.0 0.25 11.0 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.1 EGC32412.1 - 1.5e-05 24.9 10.0 1.5e-05 24.9 6.9 3.6 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC32412.1 - 0.00051 19.8 7.7 0.00051 19.8 5.4 2.9 2 1 0 2 2 2 1 Ring finger domain Sina PF03145.11 EGC32412.1 - 0.0018 17.9 8.1 0.0018 17.9 5.6 1.9 2 0 0 2 2 2 1 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EGC32412.1 - 0.0024 17.5 11.2 0.0024 17.5 7.8 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 EGC32412.1 - 0.011 16.1 5.4 0.011 16.1 3.7 3.6 3 2 1 4 4 4 0 TRAF-type zinc finger Prok-RING_4 PF14447.1 EGC32412.1 - 3.9 7.0 17.0 0.33 10.5 3.5 3.1 2 1 1 3 3 3 0 Prokaryotic RING finger family 4 Methyltransf_2 PF00891.13 EGC32413.1 - 5.5e-54 182.9 0.0 8.2e-54 182.3 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_12 PF08242.7 EGC32413.1 - 0.0065 16.9 0.1 0.028 14.8 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain HTH_28 PF13518.1 EGC32413.1 - 0.013 15.4 0.0 0.044 13.7 0.0 1.8 2 0 0 2 2 2 0 Helix-turn-helix domain Methyltransf_18 PF12847.2 EGC32413.1 - 0.014 15.9 0.0 0.029 14.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32413.1 - 0.015 15.0 0.0 0.051 13.2 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase domain HTH_23 PF13384.1 EGC32413.1 - 0.019 14.6 0.0 0.038 13.6 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGC32413.1 - 0.06 12.8 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Sigma-70, region 4 TrmB PF01978.14 EGC32413.1 - 0.067 12.9 0.0 0.16 11.6 0.0 1.6 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Cys_Met_Meta_PP PF01053.15 EGC32413.1 - 0.12 10.6 0.0 0.19 10.0 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Methyltransf_11 PF08241.7 EGC32413.1 - 0.13 12.8 0.0 6.4 7.3 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase domain Cpn60_TCP1 PF00118.19 EGC32414.1 - 6.4e-32 110.8 9.9 3e-18 65.7 1.1 2.2 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family FAM176 PF14851.1 EGC32414.1 - 0.11 12.1 2.8 0.22 11.2 0.2 2.7 2 1 1 3 3 3 0 FAM176 family Acyl_transf_1 PF00698.16 EGC32415.1 - 7.6e-26 91.1 0.0 2e-16 60.2 0.0 2.2 2 0 0 2 2 2 2 Acyl transferase domain DUF1162 PF06650.7 EGC32416.1 - 1.2e-40 139.4 7.4 1.2e-40 139.4 5.1 5.5 6 0 0 6 6 6 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGC32416.1 - 2.3e-25 88.4 0.2 3.3e-24 84.7 0.1 3.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC32416.1 - 0.0046 17.0 0.0 0.013 15.5 0.0 1.8 1 0 0 1 1 1 1 ATG C terminal domain TIG PF01833.19 EGC32417.1 - 8.5e-06 25.6 13.0 7.7e-05 22.6 4.4 2.9 1 1 1 2 2 2 2 IPT/TIG domain zf-TRAF PF02176.13 EGC32418.1 - 1.7e-06 28.3 8.6 0.00024 21.4 0.8 4.3 3 1 2 5 5 5 3 TRAF-type zinc finger Sina PF03145.11 EGC32418.1 - 6.6e-06 25.9 1.0 9.5e-06 25.4 0.7 1.2 1 0 0 1 1 1 1 Seven in absentia protein family zf-C3HC4_4 PF15227.1 EGC32418.1 - 0.00023 20.9 13.2 0.00023 20.9 9.1 3.2 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC32418.1 - 0.00031 20.3 9.1 0.00031 20.3 6.3 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC32418.1 - 0.00055 19.9 12.9 0.00055 19.9 9.0 3.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC32418.1 - 0.00078 19.0 11.8 0.00078 19.0 8.2 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC32418.1 - 0.0021 17.6 8.4 0.0021 17.6 5.8 2.7 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC32418.1 - 0.0095 15.7 10.8 0.0095 15.7 7.5 3.0 1 1 2 3 3 3 1 Ring finger domain zf-RING_UBOX PF13445.1 EGC32418.1 - 0.021 14.5 6.9 0.021 14.5 4.8 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zinc_ribbon_5 PF13719.1 EGC32418.1 - 0.048 13.2 3.4 5.2 6.7 0.0 3.3 3 0 0 3 3 3 0 zinc-ribbon domain zf-U11-48K PF05253.7 EGC32418.1 - 0.057 13.1 0.8 0.46 10.2 0.1 3.0 2 0 0 2 2 2 0 U11-48K-like CHHC zinc finger Zn-ribbon_8 PF09723.5 EGC32418.1 - 0.1 12.5 2.0 1.9 8.5 0.0 3.3 3 0 0 3 3 3 0 Zinc ribbon domain Prok-RING_4 PF14447.1 EGC32418.1 - 0.51 9.9 8.6 2.1 7.9 5.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 Rtf2 PF04641.7 EGC32418.1 - 0.87 8.7 5.2 11 5.1 3.6 2.1 1 1 1 2 2 2 0 Rtf2 RING-finger Zn_Tnp_IS91 PF14319.1 EGC32418.1 - 1.9 8.0 8.1 1.8 8.1 1.4 2.8 2 1 1 3 3 3 0 Transposase zinc-binding domain zinc_ribbon_4 PF13717.1 EGC32418.1 - 4 7.2 9.4 5.8 6.6 0.0 3.3 4 0 0 4 4 3 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGC32418.1 - 6.8 6.0 11.4 0.37 10.0 0.2 3.9 4 0 0 4 4 4 0 zinc-ribbon domain FA_desaturase PF00487.19 EGC32419.1 - 4e-23 82.1 19.8 6.7e-23 81.4 13.7 1.3 1 0 0 1 1 1 1 Fatty acid desaturase Lipid_DES PF08557.5 EGC32419.1 - 0.037 13.2 0.1 0.066 12.4 0.1 1.4 1 0 0 1 1 1 0 Sphingolipid Delta4-desaturase (DES) SPX PF03105.14 EGC32420.1 - 8.4e-24 84.8 18.9 1.2e-12 48.1 7.5 2.4 1 1 1 2 2 2 2 SPX domain DUF3291 PF11695.3 EGC32420.1 - 0.06 12.7 0.3 0.12 11.8 0.1 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3291) Pkinase PF00069.20 EGC32422.1 - 2.9e-24 85.6 5.7 2.9e-24 85.6 4.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32422.1 - 5.6e-12 45.2 1.7 9.7e-12 44.4 1.2 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC32422.1 - 0.00019 20.5 0.0 0.00033 19.7 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC32422.1 - 0.0041 16.4 0.1 0.0092 15.3 0.1 1.5 1 0 0 1 1 1 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EGC32422.1 - 0.0042 16.0 0.0 0.025 13.5 0.0 2.0 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC32422.1 - 0.039 13.6 0.0 1.2 8.7 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Peptidase_M8 PF01457.11 EGC32423.1 - 1.1e-66 225.3 11.0 1.3e-66 225.0 7.6 1.1 1 0 0 1 1 1 1 Leishmanolysin DUF2483 PF10656.4 EGC32423.1 - 0.22 11.6 2.1 0.8 9.8 0.0 2.7 3 0 0 3 3 3 0 Hypothetical protein of unknown function (DUF2483) Tricorn_C1 PF14684.1 EGC32424.1 - 0.039 13.8 0.0 11 5.9 0.0 2.7 2 0 0 2 2 2 0 Tricorn protease C1 domain Mad3_BUB1_I PF08311.7 EGC32425.1 - 9.1e-39 132.1 1.8 2.7e-38 130.5 1.3 1.9 1 0 0 1 1 1 1 Mad3/BUB1 homology region 1 TPR_8 PF13181.1 EGC32425.1 - 0.0005 19.6 0.3 0.0027 17.3 0.2 2.3 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32425.1 - 0.0037 17.0 0.3 0.0085 15.9 0.2 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32425.1 - 0.026 14.1 1.0 0.058 13.0 0.7 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat FNIP PF05725.7 EGC32426.1 - 9.2e-55 182.3 41.6 2.5e-14 52.9 0.1 8.6 6 2 1 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 EGC32426.1 - 0.00012 21.9 14.5 15 5.6 0.0 8.5 6 3 4 10 10 10 3 Protein of unknown function (DUF1769) IBR PF01485.16 EGC32427.1 - 1.2e-15 57.1 40.8 2.2e-10 40.2 2.2 4.6 4 1 1 5 5 5 3 IBR domain CUE PF02845.11 EGC32427.1 - 3e-11 42.5 0.3 6e-11 41.6 0.2 1.6 1 0 0 1 1 1 1 CUE domain zf-RING_2 PF13639.1 EGC32427.1 - 0.0001 22.0 7.1 0.0001 22.0 4.9 3.9 3 2 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGC32427.1 - 0.00012 21.7 7.9 0.00012 21.7 5.5 4.9 3 2 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32427.1 - 0.00029 20.5 6.9 0.00029 20.5 4.8 4.1 3 2 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC32427.1 - 0.0028 17.6 7.4 0.0028 17.6 5.1 4.6 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) UBA PF00627.26 EGC32427.1 - 0.0054 16.5 0.0 0.014 15.2 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain GST_N_2 PF13409.1 EGC32428.1 - 1.7e-21 75.9 0.0 3.2e-21 75.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC32428.1 - 6.3e-11 42.0 0.0 1.1e-10 41.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC32428.1 - 5.1e-10 39.2 0.2 8.6e-10 38.4 0.2 1.5 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC32428.1 - 3.3e-05 24.2 0.0 5.5e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC32428.1 - 0.00057 20.0 0.1 0.0084 16.3 0.1 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Bcl-2_3 PF15286.1 EGC32428.1 - 0.07 13.5 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 Apoptosis regulator M11, B cell 2 leukaemia/lymphoma like BAG PF02179.11 EGC32429.1 - 0.0014 18.6 1.3 0.0014 18.6 0.9 2.6 3 0 0 3 3 3 1 BAG domain CTDII PF01556.13 EGC32429.1 - 0.039 13.8 0.0 0.29 11.0 0.0 2.4 3 0 0 3 3 3 0 DnaJ C terminal domain Reo_sigmaC PF04582.7 EGC32429.1 - 0.45 9.6 2.2 0.73 8.9 1.5 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein V-SNARE PF05008.10 EGC32429.1 - 0.86 9.8 5.7 2.8 8.1 0.5 3.1 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF3671 PF12420.3 EGC32430.1 - 0.0062 16.4 4.1 0.016 15.1 0.6 2.7 2 0 0 2 2 2 1 Protein of unknown function SNase PF00565.12 EGC32431.1 - 2.5e-53 178.8 0.4 2.8e-16 59.7 0.0 5.5 5 0 0 5 5 5 5 Staphylococcal nuclease homologue TUDOR PF00567.19 EGC32431.1 - 1.6e-10 40.8 0.0 3.7e-10 39.6 0.0 1.7 1 0 0 1 1 1 1 Tudor domain SR-25 PF10500.4 EGC32431.1 - 9.3 5.6 16.9 0.67 9.3 5.3 2.5 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Methyltransf_8 PF05148.10 EGC32432.1 - 8.8e-80 267.4 0.8 9.8e-80 267.2 0.6 1.0 1 0 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_11 PF08241.7 EGC32432.1 - 6.7e-08 32.9 0.0 1.5e-07 31.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC32432.1 - 0.00017 21.0 0.3 0.0032 16.8 0.0 2.0 1 1 1 2 2 2 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGC32432.1 - 0.00042 19.9 1.0 0.32 10.5 0.0 2.3 1 1 1 2 2 2 2 Methyltransferase domain MetW PF07021.7 EGC32432.1 - 0.0036 16.7 0.1 0.0055 16.0 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EGC32432.1 - 0.015 14.9 0.1 0.035 13.7 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Ubie_methyltran PF01209.13 EGC32432.1 - 0.04 13.0 0.1 5.4 6.0 0.0 2.1 1 1 1 2 2 2 0 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGC32432.1 - 0.067 13.5 0.1 0.15 12.4 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase domain Sel1 PF08238.7 EGC32433.1 - 1.2e-08 35.3 5.9 0.00055 20.4 0.5 3.8 3 0 0 3 3 3 2 Sel1 repeat TPR_11 PF13414.1 EGC32433.1 - 3.6e-05 23.3 5.3 0.0001 21.8 0.6 2.5 2 1 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EGC32433.1 - 0.00066 19.5 3.5 0.00095 19.0 0.7 2.1 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32433.1 - 0.0025 17.8 1.0 0.0068 16.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32433.1 - 0.0042 17.4 0.2 2.2 8.9 0.1 3.2 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32433.1 - 0.006 16.1 1.2 0.006 16.1 0.8 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32433.1 - 0.018 14.8 0.2 0.2 11.5 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32433.1 - 0.02 14.7 0.6 0.02 14.7 0.4 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC32433.1 - 0.047 13.8 6.1 0.12 12.5 3.6 2.2 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 GIDE PF12483.3 EGC32434.1 - 0.034 13.5 0.4 0.061 12.6 0.2 1.5 1 0 0 1 1 1 0 E3 Ubiquitin ligase TAP42 PF04177.7 EGC32435.1 - 7.4e-69 232.2 12.9 2.6e-68 230.4 8.9 1.7 1 1 0 1 1 1 1 TAP42-like family Glyco_hydro_16 PF00722.16 EGC32436.1 - 7.4e-08 31.8 0.2 1.6e-07 30.7 0.2 1.6 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 Glyco_hydro_16 PF00722.16 EGC32437.1 - 9.7e-06 24.9 1.5 1.1e-05 24.8 0.2 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 PRELI PF04707.9 EGC32438.1 - 6.5e-29 100.5 0.4 8.5e-29 100.1 0.2 1.1 1 0 0 1 1 1 1 PRELI-like family WD40 PF00400.27 EGC32439.1 - 2.9e-48 160.0 23.4 4.3e-08 32.7 0.6 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGC32439.1 - 5.7e-11 41.9 0.2 1.3e-10 40.7 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC32439.1 - 1.5e-08 34.0 0.0 3.1e-08 33.0 0.0 1.6 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGC32439.1 - 0.0076 14.4 17.2 0.79 7.7 0.1 5.2 2 2 2 5 5 5 3 Nucleoporin Nup120/160 PRANC PF09372.5 EGC32439.1 - 0.0091 15.9 7.9 0.028 14.3 5.5 1.9 1 0 0 1 1 1 1 PRANC domain Histone PF00125.19 EGC32440.1 - 3.2e-20 72.0 0.0 3.9e-20 71.7 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC32440.1 - 1.9e-08 34.2 0.0 2.4e-08 33.8 0.0 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIIF_beta PF02270.10 EGC32441.1 - 1.2e-51 176.1 0.8 1.1e-37 130.4 0.1 2.0 1 1 1 2 2 2 2 Transcription initiation factor IIF, beta subunit OTU PF02338.14 EGC32443.1 - 2.2e-19 70.2 0.5 2.2e-19 70.2 0.3 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease UBA PF00627.26 EGC32443.1 - 7.5e-05 22.4 0.0 0.00027 20.6 0.0 2.1 1 0 0 1 1 1 1 UBA/TS-N domain CUE PF02845.11 EGC32443.1 - 0.011 15.2 0.6 0.028 13.9 0.1 2.0 2 0 0 2 2 2 0 CUE domain SSP160 PF06933.6 EGC32443.1 - 0.47 8.3 21.4 0.022 12.7 7.9 2.6 3 0 0 3 3 3 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC32443.1 - 0.52 10.0 23.3 0.28 10.9 12.9 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGC32443.1 - 1.2 8.9 17.6 32 4.3 12.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) WD40 PF00400.27 EGC32444.1 - 6.5e-20 70.2 10.0 9.7e-07 28.4 0.2 6.5 6 0 0 6 6 6 4 WD domain, G-beta repeat TPR_7 PF13176.1 EGC32444.1 - 0.06 13.1 0.0 0.15 11.8 0.0 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC32444.1 - 0.077 13.1 0.6 3 8.0 0.1 2.6 2 0 0 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGC32444.1 - 0.12 11.9 0.6 0.36 10.5 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF2201_N PF13203.1 EGC32445.1 - 1.2 8.2 4.8 1.3 8.1 3.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain Smg4_UPF3 PF03467.10 EGC32446.1 - 6.2e-12 45.8 2.5 6.2e-12 45.8 1.7 1.9 1 1 0 2 2 2 1 Smg-4/UPF3 family MIP-T3 PF10243.4 EGC32446.1 - 0.6 8.5 33.9 0.78 8.1 23.5 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 UPF0172 PF03665.8 EGC32446.1 - 0.63 9.4 6.0 0.15 11.4 0.9 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0172) Macoilin PF09726.4 EGC32446.1 - 1.6 6.9 20.4 1.9 6.6 14.2 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF4551 PF15087.1 EGC32446.1 - 9.5 4.4 22.4 12 4.1 15.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) COesterase PF00135.23 EGC32447.1 - 2.7e-17 62.6 0.0 4.4e-17 62.0 0.0 1.3 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_5 PF12695.2 EGC32447.1 - 5.6e-14 52.1 0.0 8.1e-14 51.5 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGC32447.1 - 5.1e-12 45.8 0.0 6.8e-12 45.4 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC32447.1 - 7.1e-06 25.3 0.2 0.061 12.5 0.0 2.7 2 1 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGC32447.1 - 3.7e-05 23.7 0.0 6.9e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DUF2424 PF10340.4 EGC32447.1 - 0.00026 19.7 0.8 0.00039 19.1 0.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Chlorophyllase2 PF12740.2 EGC32447.1 - 0.014 14.2 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EGC32447.1 - 0.025 14.1 0.0 0.049 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipase (class 3) PAF-AH_p_II PF03403.8 EGC32447.1 - 0.12 10.6 0.2 1 7.6 0.0 2.0 1 1 0 2 2 2 0 Platelet-activating factor acetylhydrolase, isoform II Abhydrolase_1 PF00561.15 EGC32447.1 - 0.13 11.8 0.1 0.39 10.2 0.1 1.7 2 0 0 2 2 2 0 alpha/beta hydrolase fold PGAP1 PF07819.8 EGC32447.1 - 0.15 11.6 0.6 0.38 10.2 0.4 1.7 1 1 0 1 1 1 0 PGAP1-like protein CBM49 PF09478.5 EGC32448.1 - 1.3e-18 66.8 0.1 1.6e-18 66.5 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 UbiA PF01040.13 EGC32449.1 - 1.2e-10 41.0 21.7 1.7e-10 40.5 15.0 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family MCM PF00493.18 EGC32451.1 - 2.4e-139 463.7 0.9 7.2e-139 462.1 0.7 1.8 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGC32451.1 - 2.7e-15 56.9 0.1 2.7e-15 56.9 0.1 3.8 4 1 0 4 4 4 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC32451.1 - 1.7e-08 33.8 0.0 4.4e-07 29.2 0.0 2.6 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC32451.1 - 3.4e-06 26.8 0.6 1.1e-05 25.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC32451.1 - 1.4e-05 24.7 0.0 0.0038 16.8 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) MCM2_N PF12619.3 EGC32451.1 - 0.0016 18.4 38.0 0.0016 18.4 26.3 2.8 2 1 1 3 3 3 1 Mini-chromosome maintenance protein 2 Sigma54_activat PF00158.21 EGC32451.1 - 0.016 14.7 0.0 1.6 8.2 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF1183 PF06682.7 EGC32452.1 - 0.014 15.0 4.8 0.025 14.1 3.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ctr PF04145.10 EGC32452.1 - 0.064 13.3 0.3 0.064 13.3 0.2 2.1 2 1 0 2 2 2 0 Ctr copper transporter family SIT PF15330.1 EGC32452.1 - 0.25 11.4 7.3 0.052 13.6 1.5 2.2 1 1 1 2 2 2 0 SHP2-interacting transmembrane adaptor protein, SIT PAT1 PF09770.4 EGC32452.1 - 0.51 8.5 25.2 0.58 8.3 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF1443 PF07280.6 EGC32452.1 - 4.7 6.8 7.9 0.68 9.5 2.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1443) RNA_pol_Rpb4 PF03874.11 EGC32454.1 - 5.7e-16 58.5 1.6 7.2e-16 58.2 1.1 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb4 DUF2757 PF10955.3 EGC32454.1 - 0.01 16.0 0.1 0.021 15.0 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2757) Glyco_hydro_38 PF01074.17 EGC32455.1 - 3e-92 308.7 1.1 5e-92 308.0 0.8 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGC32455.1 - 6.6e-69 232.8 8.3 8.5e-69 232.5 5.8 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGC32455.1 - 1e-21 76.9 0.5 4.7e-21 74.7 0.2 2.3 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Mo25 PF08569.6 EGC32455.1 - 0.005 15.9 0.0 0.011 14.8 0.0 1.4 1 0 0 1 1 1 1 Mo25-like Brix PF04427.13 EGC32457.1 - 3.3e-41 141.0 1.2 5.2e-41 140.4 0.8 1.3 1 0 0 1 1 1 1 Brix domain EssA PF10661.4 EGC32457.1 - 0.074 12.7 1.1 0.14 11.8 0.7 1.5 1 0 0 1 1 1 0 WXG100 protein secretion system (Wss), protein EssA polyprenyl_synt PF00348.12 EGC32459.1 - 8.2e-48 162.5 0.0 1.9e-47 161.2 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase polyprenyl_synt PF00348.12 EGC32460.1 - 8.8e-48 162.4 0.0 2.1e-47 161.1 0.0 1.5 1 1 0 1 1 1 1 Polyprenyl synthetase HMG-CoA_red PF00368.13 EGC32461.1 - 3.3e-165 549.2 3.5 4.1e-165 548.9 2.4 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase NUDIX PF00293.23 EGC32462.1 - 2.6e-11 43.2 0.0 5.3e-11 42.3 0.0 1.6 1 1 0 1 1 1 1 NUDIX domain DUF3527 PF12043.3 EGC32462.1 - 0.007 15.9 2.8 0.0089 15.6 2.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3527) DASH_Spc19 PF08287.6 EGC32462.1 - 0.02 14.5 1.4 0.043 13.4 1.0 1.6 1 0 0 1 1 1 0 Spc19 GAGA_bind PF06217.7 EGC32462.1 - 0.22 11.4 7.0 0.34 10.8 4.2 1.4 1 1 0 1 1 1 0 GAGA binding protein-like family BRF1 PF07741.8 EGC32462.1 - 4.7 7.4 12.0 1.1 9.5 4.2 2.6 3 0 0 3 3 3 0 Brf1-like TBP-binding domain Laminin_G_3 PF13385.1 EGC32463.1 - 3.9e-11 43.4 0.6 1.2e-10 41.8 0.4 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily RasGAP PF00616.14 EGC32464.1 - 2.7e-50 170.7 0.8 2.7e-50 170.7 0.6 2.6 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGC32464.1 - 8.4e-33 113.0 9.7 2.7e-32 111.3 6.7 2.0 1 0 0 1 1 1 1 RasGAP C-terminus Latarcin PF10279.4 EGC32464.1 - 0.19 11.9 3.4 1.3 9.3 1.5 2.7 1 1 1 2 2 2 0 Latarcin precursor DUF4045 PF13254.1 EGC32464.1 - 4.2 6.5 8.3 0.13 11.4 1.2 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4045) Snapin_Pallidin PF14712.1 EGC32464.1 - 5.3 7.4 15.8 0.1 12.9 2.3 4.1 4 1 1 5 5 5 0 Snapin/Pallidin Abhydrolase_1 PF00561.15 EGC32465.1 - 5.9e-26 91.4 0.0 2e-24 86.4 0.0 2.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC32465.1 - 2.4e-19 70.1 0.0 3.4e-19 69.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC32465.1 - 2.9e-14 53.0 0.0 1.4e-13 50.8 0.0 1.9 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC32465.1 - 0.00091 18.5 0.0 0.63 9.2 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Peptidase_S28 PF05577.7 EGC32465.1 - 0.0051 15.4 0.0 0.0082 14.7 0.0 1.2 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Hydrolase_4 PF12146.3 EGC32465.1 - 0.008 16.0 0.1 0.026 14.3 0.0 2.0 2 0 0 2 2 2 1 Putative lysophospholipase His_Phos_1 PF00300.17 EGC32467.1 - 5.8e-24 84.9 0.5 5.9e-23 81.7 0.2 2.3 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) WD40 PF00400.27 EGC32468.1 - 7.6e-46 152.4 14.7 2.7e-13 49.2 0.0 7.6 8 0 0 8 8 8 6 WD domain, G-beta repeat DivIC PF04977.10 EGC32468.1 - 0.00092 18.6 1.1 0.0018 17.7 0.7 1.4 1 0 0 1 1 1 1 Septum formation initiator Prefoldin_2 PF01920.15 EGC32468.1 - 0.039 13.7 2.2 0.067 12.9 1.5 1.3 1 0 0 1 1 1 0 Prefoldin subunit bZIP_1 PF00170.16 EGC32468.1 - 0.042 13.7 1.4 0.084 12.8 1.0 1.4 1 0 0 1 1 1 0 bZIP transcription factor FlaC_arch PF05377.6 EGC32468.1 - 0.053 13.4 0.4 0.14 12.0 0.3 1.7 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) BicD PF09730.4 EGC32468.1 - 0.13 10.5 0.7 0.21 9.9 0.5 1.2 1 0 0 1 1 1 0 Microtubule-associated protein Bicaudal-D SRR1 PF07985.7 EGC32469.1 - 6e-17 61.3 0.1 9.7e-17 60.6 0.0 1.3 1 0 0 1 1 1 1 SRR1 Ribosomal_S17e PF00833.13 EGC32469.1 - 0.009 15.7 0.1 0.015 15.0 0.1 1.3 1 0 0 1 1 1 1 Ribosomal S17 Acetyltransf_1 PF00583.19 EGC32470.1 - 9.4e-10 38.4 0.0 1.7e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGC32470.1 - 5.6e-09 35.9 0.0 7e-09 35.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC32470.1 - 4.3e-06 26.8 0.0 8.2e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC32470.1 - 3.1e-05 24.0 0.0 3.8e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGC32470.1 - 0.002 17.3 0.0 0.0033 16.6 0.0 1.4 1 0 0 1 1 1 1 MOZ/SAS family UPF0086 PF01868.11 EGC32471.1 - 2.4e-23 81.6 0.0 6.1e-23 80.2 0.0 1.7 1 0 0 1 1 1 1 Domain of unknown function UPF0086 DRY_EERY PF09750.4 EGC32471.1 - 3.2 7.8 7.7 15 5.6 2.0 2.3 2 0 0 2 2 2 0 Alternative splicing regulator HSP20 PF00011.16 EGC32473.1 - 3.9e-07 29.8 0.0 5.2e-07 29.4 0.0 1.1 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Actin PF00022.14 EGC32474.1 - 6.1e-37 126.9 0.0 1.2e-21 76.6 0.0 2.3 2 0 0 2 2 2 2 Actin Hydrolase_3 PF08282.7 EGC32474.1 - 0.053 13.0 2.1 0.048 13.2 0.4 1.6 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase CPL PF08144.6 EGC32475.1 - 3.2e-14 53.0 0.6 6.7e-12 45.4 0.0 4.1 4 1 0 4 4 4 1 CPL (NUC119) domain PUF PF00806.14 EGC32475.1 - 0.00027 20.2 3.3 1.2 8.7 0.1 5.0 4 1 0 4 4 4 2 Pumilio-family RNA binding repeat Oxidored_FMN PF00724.15 EGC32476.1 - 4e-75 252.9 0.0 5.2e-75 252.5 0.0 1.1 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGC32476.1 - 0.017 13.9 0.0 0.25 10.1 0.0 2.1 2 0 0 2 2 2 0 Dihydrouridine synthase (Dus) Big_2 PF02368.13 EGC32478.1 - 1.5e-19 69.6 29.5 4.5e-05 23.2 0.1 10.9 13 0 0 13 13 13 5 Bacterial Ig-like domain (group 2) T2SS-T3SS_pil_N PF13629.1 EGC32478.1 - 0.0056 16.1 13.6 0.036 13.5 0.0 6.4 6 0 0 6 6 6 2 Pilus formation protein N terminal region DDE_Tnp_4 PF13359.1 EGC32479.1 - 0.00071 19.2 0.0 0.001 18.6 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Aldedh PF00171.17 EGC32480.1 - 6.9e-09 34.5 0.0 7.5e-09 34.4 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family GSH-S_ATP PF02955.11 EGC32482.1 - 0.089 11.9 0.1 0.12 11.5 0.1 1.2 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, ATP-grasp domain tRNA-synt_1c PF00749.16 EGC32483.1 - 4.7e-109 363.8 0.0 8e-109 363.0 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGC32483.1 - 2.6e-57 193.2 0.5 7.6e-57 191.7 0.4 1.9 1 0 0 1 1 1 1 tRNA synthetases class I (E and Q), anti-codon binding domain tRNA_synt_1c_R1 PF04558.10 EGC32483.1 - 2.8e-54 183.0 3.1 5.1e-54 182.2 2.2 1.4 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_synt_1c_R2 PF04557.10 EGC32483.1 - 1.6e-12 47.9 1.5 4.6e-12 46.4 1.0 1.9 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 2 WD40 PF00400.27 EGC32484.1 - 4.4e-47 156.3 14.4 7.7e-12 44.6 0.1 7.4 7 0 0 7 7 7 6 WD domain, G-beta repeat SSP160 PF06933.6 EGC32484.1 - 0.97 7.3 17.1 1.2 6.9 11.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC32484.1 - 2.6 7.8 26.8 4.3 7.1 18.6 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein vWA-TerF-like PF10138.4 EGC32485.1 - 6.9e-11 42.3 0.0 8.5e-11 42.0 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC32485.1 - 6.6e-10 38.9 0.0 8.5e-10 38.6 0.0 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC32485.1 - 2.7e-09 37.3 0.0 5.7e-09 36.3 0.0 1.5 1 1 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGC32485.1 - 2e-05 24.3 0.0 3e-05 23.7 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF2101 PF09874.4 EGC32485.1 - 0.053 12.9 0.2 0.098 12.1 0.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2101) vWA-TerF-like PF10138.4 EGC32486.1 - 3.4e-13 49.8 0.0 4.3e-13 49.5 0.0 1.1 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC32486.1 - 1.5e-10 41.0 0.1 1.9e-10 40.7 0.1 1.1 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC32486.1 - 3.2e-10 40.3 0.0 4.7e-10 39.8 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGC32486.1 - 4.9e-09 36.0 0.0 7.9e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain FNIP PF05725.7 EGC32488.1 - 4.2e-15 55.4 12.1 6.1e-08 32.4 1.9 4.9 2 2 3 5 5 5 5 FNIP Repeat CHCH PF06747.8 EGC32489.1 - 2.5e-07 30.4 7.8 4.1e-07 29.7 5.4 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGC32489.1 - 0.046 13.7 2.6 0.07 13.1 1.8 1.3 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 NDUF_B7 PF05676.8 EGC32489.1 - 0.07 12.5 1.3 0.09 12.2 0.9 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) YqzE PF14038.1 EGC32490.1 - 1.1 9.0 5.0 1.2 8.9 0.4 2.5 2 1 1 3 3 3 0 YqzE-like protein DUF2660 PF10859.3 EGC32492.1 - 0.93 9.7 12.1 0.42 10.8 0.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2660) SAP PF02037.22 EGC32493.1 - 0.064 12.7 0.1 0.2 11.2 0.1 1.9 1 0 0 1 1 1 0 SAP domain DUF1664 PF07889.7 EGC32493.1 - 0.067 12.9 13.9 1 9.1 1.9 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Macoilin PF09726.4 EGC32493.1 - 0.09 11.0 31.3 0.12 10.6 21.7 1.1 1 0 0 1 1 1 0 Transmembrane protein Na_trans_assoc PF06512.8 EGC32494.1 - 0.011 15.7 1.1 0.013 15.4 0.8 1.0 1 0 0 1 1 1 0 Sodium ion transport-associated RNA_polI_A14 PF08203.6 EGC32494.1 - 0.23 11.7 1.6 0.38 11.0 1.1 1.6 1 1 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 SRI PF08236.6 EGC32494.1 - 0.71 9.8 4.2 1.1 9.2 2.9 1.3 1 1 0 1 1 1 0 SRI (Set2 Rpb1 interacting) domain Fusion_gly PF00523.13 EGC32495.1 - 0.021 12.9 0.1 0.021 12.9 0.1 1.0 1 0 0 1 1 1 0 Fusion glycoprotein F0 Glyco_hydro_18 PF00704.23 EGC32497.1 - 0.018 14.4 1.3 0.021 14.2 0.9 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 18 LSM PF01423.17 EGC32498.1 - 1.8e-16 59.4 0.0 2.2e-16 59.1 0.0 1.1 1 0 0 1 1 1 1 LSM domain EXS PF03124.9 EGC32499.1 - 2.8e-79 266.6 34.3 4.3e-79 266.0 23.8 1.3 1 0 0 1 1 1 1 EXS family SPX PF03105.14 EGC32499.1 - 1.5e-19 70.8 52.5 1.5e-19 70.8 36.4 3.9 2 1 0 2 2 2 1 SPX domain MHC2-interact PF09307.5 EGC32499.1 - 0.061 13.1 0.1 0.7 9.6 0.0 2.6 2 0 0 2 2 2 0 CLIP, MHC2 interacting 7tm_1 PF00001.16 EGC32500.1 - 0.00013 21.1 8.5 0.019 14.1 4.4 3.0 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) Neur_chan_memb PF02932.11 EGC32500.1 - 0.00024 21.0 1.0 0.00036 20.4 0.7 1.3 1 0 0 1 1 1 1 Neurotransmitter-gated ion-channel transmembrane region Zip PF02535.17 EGC32500.1 - 0.0043 16.0 1.9 0.011 14.7 1.3 1.7 1 0 0 1 1 1 1 ZIP Zinc transporter Menin PF05053.8 EGC32500.1 - 0.15 10.1 4.9 0.18 9.9 3.4 1.1 1 0 0 1 1 1 0 Menin NHS PF15273.1 EGC32500.1 - 0.8 8.2 14.0 1 7.9 9.7 1.0 1 0 0 1 1 1 0 NHS-like Sterol_MT_C PF08498.5 EGC32501.1 - 7.5e-21 73.8 0.1 1.1e-20 73.2 0.0 1.3 1 0 0 1 1 1 1 Sterol methyltransferase C-terminal Methyltransf_11 PF08241.7 EGC32501.1 - 3.8e-19 68.9 0.0 7.8e-19 67.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32501.1 - 1.5e-15 57.1 0.0 2.7e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32501.1 - 1.4e-14 54.1 0.0 2.1e-14 53.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC32501.1 - 1.1e-11 44.9 0.0 2e-11 44.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC32501.1 - 6.6e-11 41.8 0.0 8.4e-11 41.4 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Ubie_methyltran PF01209.13 EGC32501.1 - 1.1e-08 34.5 0.0 1.6e-08 33.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGC32501.1 - 2.7e-08 34.1 0.0 9.4e-08 32.4 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32501.1 - 1.4e-06 28.8 0.0 3.4e-06 27.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC32501.1 - 5e-05 23.3 0.0 0.00019 21.4 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC32501.1 - 0.012 15.1 0.0 0.024 14.1 0.0 1.5 1 1 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_15 PF09445.5 EGC32501.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase Methyltransf_8 PF05148.10 EGC32501.1 - 0.02 14.5 0.0 0.05 13.2 0.0 1.6 2 0 0 2 2 2 0 Hypothetical methyltransferase MTS PF05175.9 EGC32501.1 - 0.046 13.0 0.0 0.1 11.9 0.0 1.5 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EGC32501.1 - 0.12 12.1 0.0 0.17 11.6 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF2407_C PF13373.1 EGC32502.1 - 0.028 14.3 7.0 0.099 12.5 4.8 2.0 1 0 0 1 1 1 0 DUF2407 C-terminal domain ATP_bind_3 PF01171.15 EGC32504.1 - 8.6e-17 61.2 0.0 5.6e-16 58.5 0.0 2.2 2 0 0 2 2 2 1 PP-loop family tRNA_Me_trans PF03054.11 EGC32504.1 - 0.019 13.5 0.0 0.031 12.8 0.0 1.3 1 0 0 1 1 1 0 tRNA methyl transferase TF_Zn_Ribbon PF08271.7 EGC32504.1 - 5.2 6.4 14.4 0.099 11.9 0.3 3.3 3 0 0 3 3 3 0 TFIIB zinc-binding zf-TRAF PF02176.13 EGC32505.1 - 1.4e-13 51.0 20.7 1.2e-08 35.2 4.5 3.9 2 1 2 4 4 4 3 TRAF-type zinc finger zf-RING_6 PF14835.1 EGC32505.1 - 0.28 11.0 7.4 0.074 12.8 2.0 2.3 2 0 0 2 2 2 0 zf-RING of BARD1-type protein WBP-1 PF11669.3 EGC32506.1 - 0.0059 16.6 0.0 0.017 15.2 0.0 1.7 1 0 0 1 1 1 1 WW domain-binding protein 1 Ly49 PF08391.5 EGC32506.1 - 1.2 9.2 7.1 0.55 10.3 0.1 2.7 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region Patched PF02460.13 EGC32506.1 - 3.7 5.3 5.3 9.1 4.0 0.6 2.0 2 0 0 2 2 2 0 Patched family Ly49 PF08391.5 EGC32507.1 - 0.22 11.6 1.4 0.46 10.6 0.9 1.6 1 0 0 1 1 1 0 Ly49-like protein, N-terminal region IL1 PF00340.14 EGC32507.1 - 0.52 9.7 3.9 0.65 9.4 0.1 2.4 1 1 0 2 2 2 0 Interleukin-1 / 18 WD40 PF00400.27 EGC32509.1 - 8.2e-39 130.1 17.0 8.2e-11 41.3 0.1 6.3 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGC32509.1 - 2.5e-09 37.1 3.0 0.00036 20.3 0.2 3.6 1 1 2 3 3 3 3 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGC32509.1 - 1.4e-05 23.4 1.7 5.5e-05 21.4 0.1 2.3 1 1 0 3 3 3 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGC32509.1 - 0.0041 15.4 0.1 0.32 9.2 0.1 2.2 1 1 1 2 2 2 2 Cytochrome D1 heme domain SR-25 PF10500.4 EGC32509.1 - 0.048 13.1 22.6 0.45 9.9 3.8 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein Gmad1 PF10647.4 EGC32509.1 - 0.3 10.4 3.9 1.8 7.9 0.0 3.1 2 1 2 4 4 4 0 Lipoprotein LpqB beta-propeller domain Dsh_C PF12316.3 EGC32509.1 - 1.8 8.6 15.6 1.3 9.1 2.5 2.4 2 0 0 2 2 2 0 Segment polarity protein dishevelled (Dsh) C terminal CLU PF13236.1 EGC32510.1 - 2.7e-56 190.4 0.0 1.1e-55 188.5 0.0 2.0 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 EGC32510.1 - 1.2e-07 31.8 0.0 5.3e-07 29.7 0.0 2.1 1 0 0 1 1 1 1 Translation initiation factor eIF3 subunit 135 Dimer_Tnp_hAT PF05699.9 EGC32511.1 - 0.0014 18.1 0.1 0.0021 17.6 0.0 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ArfGap PF01412.13 EGC32511.1 - 0.14 11.9 1.9 0.15 11.8 1.3 1.1 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Mhr1 PF12829.2 EGC32512.1 - 0.046 13.5 1.9 0.06 13.1 0.5 1.8 2 0 0 2 2 2 0 Transcriptional regulation of mitochondrial recombination EGF_2 PF07974.8 EGC32513.1 - 9e-06 25.7 7.5 1.7e-05 24.8 5.2 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC32513.1 - 0.00089 19.1 7.8 0.0016 18.3 5.4 1.4 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EGC32513.1 - 0.027 14.4 4.9 0.05 13.5 3.4 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain MRP_L53 PF10780.4 EGC32513.1 - 0.08 12.9 0.1 0.15 12.0 0.0 1.4 1 0 0 1 1 1 0 39S ribosomal protein L53/MRP-L53 Pox_A21 PF05323.7 EGC32514.1 - 0.021 15.1 1.7 0.076 13.4 0.7 2.0 2 0 0 2 2 2 0 Poxvirus A21 Protein RRM_3 PF08777.6 EGC32514.1 - 0.15 11.8 1.5 0.26 11.1 1.0 1.5 1 0 0 1 1 1 0 RNA binding motif DUF3642 PF12182.3 EGC32514.1 - 2.8 8.4 11.2 1.8 9.0 5.7 2.1 2 1 0 2 2 2 0 Bacterial lipoprotein EF1G PF00647.14 EGC32515.1 - 5e-38 129.0 0.0 1.1e-37 128.0 0.0 1.6 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_N PF02798.15 EGC32515.1 - 1.5e-12 47.5 0.0 1.5e-12 47.5 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC32515.1 - 1.3e-11 44.3 2.0 2e-11 43.7 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC32515.1 - 3.8e-08 33.1 0.0 7.5e-08 32.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC32515.1 - 5.2e-08 32.9 0.0 1.3e-07 31.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC32515.1 - 3.7e-06 27.3 0.0 1.9e-05 25.0 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC32515.1 - 1.7e-05 24.6 0.0 3.7e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain OATP PF03137.15 EGC32515.1 - 1.7 6.6 3.8 0.9 7.5 0.1 1.9 1 1 1 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family zf-RING_6 PF14835.1 EGC32516.1 - 0.0049 16.6 2.0 0.0098 15.6 1.4 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-U11-48K PF05253.7 EGC32516.1 - 0.1 12.3 0.4 0.29 10.8 0.3 1.8 1 1 0 1 1 1 0 U11-48K-like CHHC zinc finger Cript PF10235.4 EGC32516.1 - 0.11 12.8 5.5 0.19 12.1 3.8 1.5 1 0 0 1 1 1 0 Microtubule-associated protein CRIPT DUF1510 PF07423.6 EGC32516.1 - 0.32 10.3 1.6 0.44 9.8 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-RING_UBOX PF13445.1 EGC32516.1 - 0.68 9.7 5.1 9.9 5.9 0.1 2.7 2 1 0 2 2 2 0 RING-type zinc-finger zf-RING_5 PF14634.1 EGC32516.1 - 1.4 8.6 10.5 0.33 10.6 4.6 2.1 2 1 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC32516.1 - 2.2 8.3 12.5 83 3.3 8.7 3.4 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) IBR PF01485.16 EGC32516.1 - 8.9 6.2 10.7 32 4.4 5.1 2.2 1 1 1 2 2 2 0 IBR domain Dimer_Tnp_hAT PF05699.9 EGC32517.1 - 3e-08 33.1 0.1 4.3e-08 32.6 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Prion PF00377.13 EGC32519.1 - 0.03 14.0 0.0 0.039 13.6 0.0 1.2 1 0 0 1 1 1 0 Prion/Doppel alpha-helical domain Ank_2 PF12796.2 EGC32520.1 - 9.2e-37 125.2 15.2 1.9e-09 37.6 0.0 8.7 4 3 2 8 8 8 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC32520.1 - 5.2e-25 87.3 10.4 0.0035 17.8 0.0 11.5 9 3 3 13 13 13 7 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32520.1 - 5.7e-21 72.5 17.0 0.089 13.0 0.0 14.4 14 3 3 17 17 17 5 Ankyrin repeat Ank_5 PF13857.1 EGC32520.1 - 3.5e-18 65.2 17.9 0.11 12.8 0.0 13.2 10 2 5 15 15 15 7 Ankyrin repeats (many copies) Ank PF00023.25 EGC32520.1 - 3.6e-15 54.9 12.4 0.013 15.2 0.1 12.8 15 0 0 15 15 15 4 Ankyrin repeat SNARE PF05739.14 EGC32523.1 - 1.4e-05 24.6 6.2 0.00019 21.0 2.1 2.8 2 0 0 2 2 2 2 SNARE domain DBINO PF13892.1 EGC32523.1 - 4.9 7.1 36.0 5.1 7.1 7.6 2.6 2 0 0 2 2 2 0 DNA-binding domain SelP_N PF04592.9 EGC32523.1 - 8.7 5.6 15.9 2.2 7.6 5.9 2.3 2 0 0 2 2 2 0 Selenoprotein P, N terminal region EF-hand_6 PF13405.1 EGC32524.1 - 2.3e-16 58.1 1.9 6.4e-07 28.7 0.0 3.6 4 1 0 4 4 4 2 EF-hand domain EF-hand_7 PF13499.1 EGC32524.1 - 1.8e-15 56.7 0.2 1.4e-07 31.4 0.0 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC32524.1 - 1.7e-14 51.9 2.1 4.9e-06 25.4 0.0 3.8 4 0 0 4 4 4 2 EF hand EF-hand_5 PF13202.1 EGC32524.1 - 2.4e-09 36.1 1.6 0.00079 18.6 0.0 3.2 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EGC32524.1 - 8e-09 34.9 1.0 1.7e-06 27.5 0.0 3.5 2 2 2 4 4 4 2 EF-hand domain pair EF-hand_9 PF14658.1 EGC32524.1 - 4.4e-06 26.5 0.0 0.11 12.4 0.0 2.3 2 0 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EGC32524.1 - 7.6e-05 22.2 0.0 0.086 12.4 0.0 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0154) EF-hand_like PF09279.6 EGC32524.1 - 9.1e-05 22.4 0.0 0.041 13.9 0.0 2.7 2 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like UPF0231 PF06062.6 EGC32524.1 - 0.017 15.0 0.6 0.75 9.6 0.0 2.2 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0231) EFhand_Ca_insen PF08726.5 EGC32524.1 - 0.021 14.7 0.0 0.048 13.6 0.0 1.6 1 1 0 1 1 1 0 Ca2+ insensitive EF hand DUF853 PF05872.7 EGC32524.1 - 0.027 12.8 0.0 0.029 12.7 0.0 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) DnaB_2 PF07261.6 EGC32524.1 - 0.1 12.2 0.0 13 5.4 0.0 2.2 1 1 1 2 2 2 0 Replication initiation and membrane attachment Coatomer_WDAD PF04053.9 EGC32525.1 - 2e-160 534.4 3.2 2e-160 534.4 0.1 2.2 2 1 1 3 3 3 1 Coatomer WD associated region WD40 PF00400.27 EGC32525.1 - 6.7e-59 193.7 6.4 4e-12 45.5 0.0 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat TPR_8 PF13181.1 EGC32525.1 - 0.01 15.5 0.7 0.16 11.8 0.0 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat DUF829 PF05705.9 EGC32527.1 - 1.4e-43 149.3 0.4 2.4e-43 148.5 0.3 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Abhydrolase_5 PF12695.2 EGC32527.1 - 0.1 12.3 0.0 0.52 10.0 0.0 1.9 1 1 0 1 1 1 0 Alpha/beta hydrolase family WD40 PF00400.27 EGC32528.1 - 7.7e-21 73.1 0.4 1.1e-08 34.6 0.0 5.5 4 0 0 4 4 4 4 WD domain, G-beta repeat F-box-like PF12937.2 EGC32528.1 - 9.5e-11 41.2 0.0 2.2e-10 40.0 0.0 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC32528.1 - 2.5e-07 30.1 0.0 8.1e-07 28.5 0.0 2.0 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EGC32528.1 - 0.027 14.8 0.4 0.18 12.1 0.0 2.5 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A Pterin_bind PF00809.17 EGC32529.1 - 8.4e-61 204.9 0.1 1.2e-59 201.2 0.0 2.6 3 1 0 3 3 3 1 Pterin binding enzyme HPPK PF01288.15 EGC32529.1 - 1e-36 125.4 0.0 2.1e-36 124.4 0.0 1.6 1 0 0 1 1 1 1 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) FolB PF02152.13 EGC32529.1 - 4.1e-24 84.9 0.1 8.1e-24 83.9 0.0 1.5 1 0 0 1 1 1 1 Dihydroneopterin aldolase Tubulin-binding PF00418.14 EGC32529.1 - 0.029 14.0 0.2 0.16 11.7 0.0 2.2 2 0 0 2 2 2 0 Tau and MAP protein, tubulin-binding repeat Trp_syntA PF00290.15 EGC32529.1 - 0.061 11.8 0.5 0.54 8.7 0.1 2.6 3 1 0 3 3 3 0 Tryptophan synthase alpha chain Beta_helix PF13229.1 EGC32530.1 - 0.0027 17.4 28.9 0.0027 17.4 20.0 6.8 2 2 3 5 5 5 2 Right handed beta helix region Adeno_E3B PF03376.9 EGC32530.1 - 0.034 14.0 1.5 0.26 11.1 0.4 2.7 2 0 0 2 2 2 0 Adenovirus E3B protein VWA_2 PF13519.1 EGC32531.1 - 3.8e-16 59.6 0.1 5.8e-16 59.0 0.1 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGC32531.1 - 1.8e-11 43.9 0.0 2.5e-11 43.4 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_CoxE PF05762.9 EGC32531.1 - 0.026 13.6 0.0 0.26 10.3 0.0 2.0 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Filamin PF00630.14 EGC32531.1 - 0.6 10.7 3.0 2.6 8.6 0.0 2.6 1 1 0 2 2 2 0 Filamin/ABP280 repeat DUF4131 PF13567.1 EGC32532.1 - 0.0075 15.6 0.1 0.0086 15.5 0.1 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4131) DUF2162 PF09930.4 EGC32532.1 - 0.042 12.9 1.4 0.051 12.7 1.0 1.1 1 0 0 1 1 1 0 Predicted transporter (DUF2162) DUF3516 PF12029.3 EGC32532.1 - 0.075 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3516) DUF3908 PF13048.1 EGC32532.1 - 0.52 10.2 5.4 0.39 10.6 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3908) DUF2418 PF10332.4 EGC32532.1 - 4.3 7.7 7.5 12 6.2 3.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2418) VWA_2 PF13519.1 EGC32533.1 - 4.9e-11 43.0 0.0 7.4e-11 42.4 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGC32533.1 - 2.9e-08 33.5 0.0 4.4e-08 32.9 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF805 PF05656.9 EGC32533.1 - 0.13 12.1 2.4 0.25 11.1 1.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF805) DUF4131 PF13567.1 EGC32533.1 - 0.38 10.1 8.7 0.055 12.8 0.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) Reticulon PF02453.12 EGC32533.1 - 1.5 8.4 16.4 0.82 9.2 9.2 2.0 1 1 1 2 2 2 0 Reticulon DUF3139 PF11337.3 EGC32533.1 - 4.1 7.7 10.6 2.3 8.5 0.7 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF3139) VWA_3 PF13768.1 EGC32534.1 - 3.9e-10 39.6 0.0 5.8e-10 39.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC32534.1 - 1.9e-08 34.6 0.0 2.7e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain DUF4131 PF13567.1 EGC32534.1 - 0.055 12.8 6.8 0.039 13.3 0.4 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) Reticulon PF02453.12 EGC32534.1 - 4.9 6.7 16.0 11 5.5 10.8 1.7 1 1 0 1 1 1 0 Reticulon Ribul_P_3_epim PF00834.14 EGC32535.1 - 4.1e-73 244.7 0.1 4.8e-73 244.5 0.1 1.0 1 0 0 1 1 1 1 Ribulose-phosphate 3 epimerase family PcrB PF01884.12 EGC32535.1 - 0.00078 18.7 0.3 0.18 11.0 0.0 2.1 1 1 1 2 2 2 2 PcrB family NanE PF04131.9 EGC32535.1 - 0.0042 16.0 0.0 0.0053 15.7 0.0 1.1 1 0 0 1 1 1 1 Putative N-acetylmannosamine-6-phosphate epimerase M20_dimer PF07687.9 EGC32535.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.4 1 1 0 1 1 1 0 Peptidase dimerisation domain QRPTase_C PF01729.14 EGC32535.1 - 0.015 14.7 0.0 0.048 13.1 0.0 1.7 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, C-terminal domain FMN_dh PF01070.13 EGC32535.1 - 0.044 12.6 0.0 0.41 9.4 0.0 2.0 2 0 0 2 2 2 0 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGC32535.1 - 0.05 12.8 0.0 1 8.5 0.0 2.1 2 0 0 2 2 2 0 Histidine biosynthesis protein DUF2624 PF11116.3 EGC32537.1 - 0.089 13.3 0.3 0.089 13.3 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2624) Viral_env_E26 PF11050.3 EGC32537.1 - 0.29 10.3 4.0 0.37 9.9 2.8 1.1 1 0 0 1 1 1 0 Virus envelope protein E26 NusB PF01029.13 EGC32537.1 - 1 9.3 6.1 1.2 9.1 3.9 1.4 1 1 0 1 1 1 0 NusB family RNA_pol_Rpb1_5 PF04998.12 EGC32537.1 - 8.4 5.5 10.8 8.8 5.4 7.5 1.0 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 5 Cofilin_ADF PF00241.15 EGC32538.1 - 5.2e-40 136.2 1.2 5.8e-40 136.1 0.8 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Ras PF00071.17 EGC32539.1 - 3.5e-39 133.7 0.1 3.5e-39 133.7 0.1 1.7 2 0 0 2 2 2 1 Ras family Miro PF08477.8 EGC32539.1 - 4e-15 56.3 0.3 2.1e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC32539.1 - 1.6e-05 24.1 0.0 2.9e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC32539.1 - 0.0005 20.0 0.6 0.0018 18.2 0.0 2.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase Nop25 PF09805.4 EGC32539.1 - 0.047 13.7 15.9 0.12 12.4 11.0 1.6 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF2422 PF10337.4 EGC32539.1 - 2.6 6.7 4.4 3.4 6.3 3.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) Vfa1 PF08432.5 EGC32539.1 - 7.4 6.5 21.5 14 5.6 14.9 1.5 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 tRNA-synt_1 PF00133.17 EGC32540.1 - 8.6e-47 159.4 0.0 1.1e-30 106.2 0.0 3.3 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1g PF09334.6 EGC32540.1 - 8.1e-21 74.1 2.4 1.1e-09 37.4 0.0 3.4 4 0 0 4 4 4 2 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGC32540.1 - 1.8e-11 44.0 0.7 8.2e-11 41.8 0.1 2.3 1 1 2 3 3 3 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGC32540.1 - 5.6e-08 32.2 0.0 1.3e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain EGF_2 PF07974.8 EGC32542.1 - 4e-05 23.6 43.4 0.0023 18.0 9.8 3.0 3 0 0 3 3 3 2 EGF-like domain SKG6 PF08693.5 EGC32542.1 - 0.0012 18.0 5.0 0.0025 17.0 3.5 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain InvH PF04741.7 EGC32542.1 - 0.046 13.5 0.6 0.11 12.3 0.4 1.6 1 0 0 1 1 1 0 InvH outer membrane lipoprotein hEGF PF12661.2 EGC32542.1 - 0.68 10.1 13.4 3 8.1 2.7 3.0 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 EGC32542.1 - 2.2 8.3 27.3 0.53 10.3 5.3 2.8 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 EGC32542.1 - 3.4 7.6 32.2 1.5 8.8 6.6 3.4 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) TIG PF01833.19 EGC32543.1 - 2.4e-09 37.0 11.2 4.6e-05 23.3 0.6 4.9 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.8 EGC32543.1 - 0.00056 20.0 29.3 0.001 19.1 6.9 3.0 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC32543.1 - 0.01 15.8 6.0 1.1 9.4 0.8 3.2 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC32543.1 - 0.55 10.2 23.8 0.23 11.3 5.4 3.2 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) zf-RING_2 PF13639.1 EGC32544.1 - 2.7e-08 33.5 11.5 2.7e-08 33.5 8.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC32544.1 - 6.6e-07 28.8 9.8 6.6e-07 28.8 6.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC32544.1 - 1e-05 25.0 14.5 1e-05 25.0 10.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32544.1 - 5.9e-05 23.0 13.1 5.9e-05 23.0 9.1 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32544.1 - 0.0035 17.0 12.3 0.0035 17.0 8.6 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC32544.1 - 0.0044 16.5 13.2 0.011 15.2 9.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGC32544.1 - 0.0066 16.5 7.6 0.021 14.9 5.3 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGC32544.1 - 0.02 14.6 3.8 0.043 13.5 2.6 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC32544.1 - 0.021 14.6 13.1 0.06 13.2 9.1 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING SpoIISA_toxin PF14171.1 EGC32544.1 - 0.42 9.8 2.7 1.9 7.6 1.9 2.1 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DivIVA PF05103.8 EGC32546.1 - 0.0038 17.2 2.2 0.0041 17.1 1.5 1.0 1 0 0 1 1 1 1 DivIVA protein Rho_Binding PF08912.6 EGC32546.1 - 0.12 12.6 4.4 0.15 12.3 3.0 1.4 1 1 0 1 1 1 0 Rho Binding TMF_DNA_bd PF12329.3 EGC32546.1 - 0.13 12.1 3.8 0.14 11.9 2.6 1.3 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Apc15p PF05841.6 EGC32547.1 - 5.1 7.8 10.8 3.4 8.4 3.3 2.5 2 1 0 2 2 2 0 Apc15p protein Mitofilin PF09731.4 EGC32548.1 - 0.22 10.1 6.9 0.24 10.0 4.7 1.0 1 0 0 1 1 1 0 Mitochondrial inner membrane protein FNIP PF05725.7 EGC32549.1 - 2.4e-207 670.7 96.9 1.1e-15 57.3 0.5 14.6 4 2 16 21 21 21 21 FNIP Repeat DUF261 PF03196.8 EGC32549.1 - 0.073 13.0 0.3 0.16 11.9 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF261 DUF1769 PF08588.5 EGC32549.1 - 0.14 12.0 35.4 6.1 6.8 0.0 11.5 6 4 7 15 15 15 0 Protein of unknown function (DUF1769) Chromo PF00385.19 EGC32550.1 - 1.3e-08 34.3 0.4 2e-08 33.7 0.3 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC32550.1 - 0.035 13.8 1.9 0.083 12.6 1.3 1.8 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain Mistic PF11458.3 EGC32550.1 - 0.18 12.2 0.9 5.1 7.5 0.1 2.4 1 1 1 2 2 2 0 Membrane-integrating protein Mistic SGT1 PF07093.6 EGC32550.1 - 0.18 10.1 1.5 0.25 9.6 0.1 1.7 1 1 1 2 2 2 0 SGT1 protein DSPc PF00782.15 EGC32551.1 - 1.6e-32 111.8 0.5 1.8e-32 111.6 0.3 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC32551.1 - 6.9e-07 28.8 0.0 8.1e-07 28.6 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGC32551.1 - 0.0059 15.5 0.1 0.0067 15.3 0.1 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EGC32551.1 - 0.0095 15.9 0.0 0.011 15.8 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate DUF1682 PF07946.9 EGC32551.1 - 0.068 12.0 0.2 0.11 11.3 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Cupin_8 PF13621.1 EGC32552.1 - 3.6e-22 79.0 1.5 3.6e-22 79.0 1.0 2.7 2 1 0 2 2 2 1 Cupin-like domain JmjC PF02373.17 EGC32552.1 - 2.5e-10 40.5 14.1 9.9e-07 29.0 2.1 4.1 3 1 0 3 3 3 2 JmjC domain, hydroxylase Cupin_4 PF08007.7 EGC32552.1 - 3e-07 30.0 0.1 9.4e-07 28.3 0.0 1.9 3 0 0 3 3 3 1 Cupin superfamily protein F-box PF00646.28 EGC32552.1 - 0.078 12.6 0.0 0.17 11.6 0.0 1.5 1 0 0 1 1 1 0 F-box domain Cupin_2 PF07883.6 EGC32552.1 - 0.093 12.2 0.0 0.34 10.4 0.0 1.8 2 0 0 2 2 2 0 Cupin domain DUF106 PF01956.11 EGC32552.1 - 0.5 9.8 12.3 0.3 10.6 2.7 2.4 2 0 0 2 2 2 0 Integral membrane protein DUF106 BING4CT PF08149.6 EGC32553.1 - 1.7e-35 120.3 0.1 7.8e-34 115.0 0.0 3.2 4 0 0 4 4 4 1 BING4CT (NUC141) domain WD40 PF00400.27 EGC32553.1 - 6.8e-09 35.2 0.4 2.1e-07 30.5 0.1 3.4 5 0 0 5 5 5 1 WD domain, G-beta repeat SPA PF08616.5 EGC32555.1 - 5.5e-12 45.3 0.1 1.3e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 Stabilization of polarity axis Avl9 PF09794.4 EGC32555.1 - 1.2e-11 43.7 0.4 4.7e-11 41.7 0.3 1.8 1 1 0 1 1 1 1 Transport protein Avl9 DENN PF02141.16 EGC32555.1 - 1.1e-05 25.2 0.8 0.00038 20.2 0.1 2.8 2 1 0 2 2 2 1 DENN (AEX-3) domain Afi1 PF07792.7 EGC32555.1 - 0.035 14.1 4.9 0.15 12.0 0.0 3.3 1 1 1 2 2 2 0 Docking domain of Afi1 for Arf3 in vesicle trafficking FtsJ PF01728.14 EGC32556.1 - 6.1e-64 215.3 0.0 8.4e-64 214.8 0.0 1.2 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_18 PF12847.2 EGC32556.1 - 0.0016 18.9 0.0 0.029 14.9 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC32556.1 - 0.0036 16.4 0.0 0.0051 15.9 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGC32556.1 - 0.069 12.7 0.0 0.48 9.9 0.0 2.1 1 1 0 1 1 1 0 Methyltransferase domain Nop25 PF09805.4 EGC32557.1 - 1.4e-08 34.8 55.9 1.4e-08 34.8 38.7 3.3 2 1 0 2 2 2 1 Nucleolar protein 12 (25kDa) Usp PF00582.21 EGC32557.1 - 9.9 6.3 17.5 0.038 14.1 3.8 2.6 2 1 1 3 3 3 0 Universal stress protein family Pkinase PF00069.20 EGC32558.1 - 8.6e-73 244.6 0.3 3.1e-72 242.8 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32558.1 - 3.6e-41 140.9 0.0 6.2e-41 140.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC32558.1 - 0.015 14.2 0.0 0.025 13.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGC32558.1 - 0.029 14.0 0.0 0.07 12.8 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family Neur_chan_memb PF02932.11 EGC32558.1 - 1.8 8.4 14.6 0.27 11.0 6.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region BTB PF00651.26 EGC32559.1 - 6.1e-11 42.2 2.4 7.5e-11 42.0 0.4 2.1 2 0 0 2 2 2 1 BTB/POZ domain SAM_2 PF07647.12 EGC32559.1 - 0.00013 21.7 0.0 0.0003 20.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC32559.1 - 0.002 18.2 0.0 0.0044 17.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Pkinase PF00069.20 EGC32560.1 - 3e-75 252.7 0.0 5e-75 252.0 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32560.1 - 1.6e-36 125.6 0.0 2.3e-36 125.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGC32560.1 - 7.2e-07 29.6 0.1 7.2e-07 29.6 0.1 2.7 2 1 0 2 2 2 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGC32560.1 - 0.00025 20.0 0.0 0.0019 17.2 0.0 2.1 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC32560.1 - 0.015 15.0 0.0 0.026 14.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC32560.1 - 0.033 13.2 0.0 0.059 12.4 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dicty_REP PF05086.7 EGC32560.1 - 4.3 4.9 18.4 5.5 4.6 12.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Ndc1_Nup PF09531.5 EGC32560.1 - 6.9 4.9 9.7 7.8 4.7 6.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 EGC32562.1 - 3.2e-19 68.8 68.8 3.9e-15 55.4 26.9 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGC32562.1 - 9e-13 47.4 27.4 9e-13 47.4 19.0 2.2 2 1 0 2 2 2 1 MFS/sugar transport protein AMP-binding PF00501.23 EGC32563.1 - 2.2e-72 243.7 0.0 5.3e-60 202.9 0.0 2.2 2 0 0 2 2 2 2 AMP-binding enzyme NAD_binding_4 PF07993.7 EGC32563.1 - 6.1e-31 107.2 0.0 1.8e-30 105.6 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Myb_DNA-binding PF00249.26 EGC32563.1 - 9.3e-14 51.2 3.3 3.3e-07 30.2 0.4 3.1 3 0 0 3 3 3 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC32563.1 - 1.1e-11 44.6 8.8 4e-07 30.0 0.4 2.9 1 1 1 2 2 2 2 Myb-like DNA-binding domain Epimerase PF01370.16 EGC32563.1 - 1.3e-06 28.0 0.0 2.5e-06 27.1 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC32563.1 - 2.9e-06 26.2 0.0 5.4e-06 25.3 0.0 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family AMP-binding_C PF13193.1 EGC32563.1 - 3.8e-05 24.5 0.0 7.2e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain RNA_pol_3_Rpc31 PF11705.3 EGC32563.1 - 0.17 11.8 11.3 0.21 11.4 6.4 2.2 2 0 0 2 2 2 0 DNA-directed RNA polymerase III subunit Rpc31 Ribosomal_60s PF00428.14 EGC32563.1 - 0.38 11.1 3.4 0.82 10.1 2.4 1.5 1 0 0 1 1 1 0 60s Acidic ribosomal protein zf-TRAF PF02176.13 EGC32564.1 - 1.4e-15 57.4 39.8 7.7e-09 35.7 5.5 5.0 1 1 4 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC32564.1 - 0.0004 20.3 9.5 0.0004 20.3 6.6 3.7 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC32564.1 - 0.0014 18.2 4.9 0.0014 18.2 3.4 3.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) PARP PF00644.15 EGC32566.1 - 0.00015 21.2 0.1 0.00023 20.6 0.1 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain SYF2 PF08231.7 EGC32568.1 - 0.15 12.1 1.5 0.19 11.8 1.1 1.1 1 0 0 1 1 1 0 SYF2 splicing factor NDUF_B7 PF05676.8 EGC32569.1 - 3.9e-25 87.0 5.9 5.1e-25 86.6 4.1 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7) Cmc1 PF08583.5 EGC32569.1 - 7.8e-05 22.3 2.8 0.00011 21.9 1.9 1.2 1 0 0 1 1 1 1 Cytochrome c oxidase biogenesis protein Cmc1 like FNIP PF05725.7 EGC32570.1 - 6.6e-106 346.0 70.5 1.2e-15 57.2 0.9 13.2 8 3 7 15 15 15 14 FNIP Repeat ACDC PF14733.1 EGC32570.1 - 0.078 13.1 1.3 58 3.8 0.0 4.6 4 0 0 4 4 4 0 AP2-coincident C-terminal ubiquitin PF00240.18 EGC32571.1 - 1.2e-103 338.5 13.0 4.7e-34 115.6 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EGC32571.1 - 2.4e-58 193.7 11.5 8.6e-19 67.0 0.3 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC32571.1 - 6e-19 68.0 4.4 0.00014 22.0 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGC32571.1 - 4.5e-14 52.4 0.1 0.0049 16.5 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGC32571.1 - 2.4e-10 40.2 0.8 0.12 12.2 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC32571.1 - 2.6e-09 37.1 0.2 0.25 11.5 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGC32571.1 - 5.6e-08 32.7 0.0 1 9.4 0.0 3.9 3 3 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EGC32571.1 - 3.4e-06 26.8 0.9 2.3 8.2 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG DUF3642 PF12182.3 EGC32571.1 - 0.00019 21.7 2.9 8.2 6.9 0.0 3.5 3 0 0 3 3 3 0 Bacterial lipoprotein Methyltrans_RNA PF04452.9 EGC32571.1 - 0.00039 19.6 0.2 0.8 8.7 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase Corona_NS2A PF05213.7 EGC32571.1 - 0.00062 19.1 0.0 10 5.3 0.0 3.0 1 1 1 3 3 3 0 Coronavirus NS2A protein FlgD_ig PF13860.1 EGC32571.1 - 0.00066 19.3 1.5 13 5.6 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain Plexin_cytopl PF08337.7 EGC32571.1 - 0.0012 17.3 4.9 3 6.0 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain Big_3_3 PF13750.1 EGC32571.1 - 0.0036 16.7 0.0 21 4.5 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Ras_bdg_2 PF14847.1 EGC32571.1 - 0.0053 16.6 0.7 34 4.4 0.0 3.4 3 0 0 3 3 3 0 Ras-binding domain of Byr2 DUF3435 PF11917.3 EGC32571.1 - 0.019 13.7 0.1 22 3.6 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) ACT_4 PF13291.1 EGC32571.1 - 0.019 15.2 0.1 73 3.8 0.0 3.2 3 0 0 3 3 3 0 ACT domain GABP-alpha PF11620.3 EGC32571.1 - 0.024 14.5 1.3 42 4.2 0.0 3.0 3 0 0 3 3 3 0 GA-binding protein alpha chain EMG1 PF03587.9 EGC32571.1 - 0.077 12.2 0.9 17 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase ECH_C PF13766.1 EGC32571.1 - 0.12 12.4 0.1 1e+02 3.0 0.0 3.1 3 0 0 3 3 3 0 2-enoyl-CoA Hydratase C-terminal region CTDII PF01556.13 EGC32571.1 - 0.29 11.0 10.2 7.3 6.5 0.3 3.3 1 1 1 3 3 3 0 DnaJ C terminal domain DUF3781 PF12636.2 EGC32571.1 - 0.3 11.0 1.8 1.1e+02 2.8 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) FERM_N PF09379.5 EGC32571.1 - 1.8 8.6 5.6 1.4e+02 2.6 0.1 4.5 3 3 0 3 3 3 0 FERM N-terminal domain VHS PF00790.14 EGC32572.1 - 1.2e-22 80.0 1.0 1.2e-22 80.0 0.7 2.1 2 1 0 2 2 2 1 VHS domain GAT PF03127.9 EGC32572.1 - 7.6e-13 48.2 0.7 7.6e-13 48.2 0.5 2.1 2 1 0 2 2 2 1 GAT domain DUF706 PF05153.10 EGC32573.1 - 1.4e-112 375.1 5.6 1.6e-112 374.9 3.9 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF706) Sdh5 PF03937.11 EGC32573.1 - 0.024 14.3 0.1 0.067 12.8 0.0 1.8 1 0 0 1 1 1 0 Flavinator of succinate dehydrogenase DUF3864 PF12980.2 EGC32573.1 - 0.1 12.7 1.1 18 5.5 0.1 2.9 2 1 1 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3864) HD PF01966.17 EGC32573.1 - 0.12 12.4 0.0 0.26 11.2 0.0 1.6 1 0 0 1 1 1 0 HD domain Ribosomal_L30 PF00327.15 EGC32574.1 - 1.1e-16 60.1 0.3 1.6e-16 59.5 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein L30p/L7e Ribosomal_S17e PF00833.13 EGC32575.1 - 8.2e-55 183.7 2.2 9.5e-55 183.5 1.5 1.1 1 0 0 1 1 1 1 Ribosomal S17 TPR_2 PF07719.12 EGC32576.1 - 2e-05 24.1 9.8 0.5 10.4 0.0 6.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC32576.1 - 2.4e-05 23.8 7.7 0.16 11.6 0.0 6.1 6 1 0 6 6 6 1 TPR repeat TPR_1 PF00515.23 EGC32576.1 - 0.00037 19.9 13.6 0.56 9.9 0.0 6.4 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32576.1 - 0.0015 18.4 4.9 0.27 11.2 0.0 4.8 6 0 0 6 6 6 1 Tetratricopeptide repeat DUF799 PF05643.6 EGC32576.1 - 0.0028 17.0 0.1 0.0067 15.7 0.1 1.6 1 0 0 1 1 1 1 Putative bacterial lipoprotein (DUF799) TPR_19 PF14559.1 EGC32576.1 - 0.0069 16.7 9.7 24 5.3 0.0 6.3 6 1 1 7 7 7 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC32576.1 - 0.022 14.8 28.2 0.023 14.8 0.4 6.4 6 0 0 6 6 6 0 Anaphase-promoting complex, cyclosome, subunit 3 FNIP PF05725.7 EGC32577.1 - 2.6e-14 52.8 60.0 1.7e-05 24.6 0.3 10.8 4 3 2 10 10 10 8 FNIP Repeat SAP30_Sin3_bdg PF13867.1 EGC32579.1 - 1.7e-15 56.6 1.1 2.6e-15 56.0 0.8 1.3 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 UDPGP PF01704.13 EGC32579.1 - 0.062 11.7 0.7 0.068 11.6 0.5 1.0 1 0 0 1 1 1 0 UTP--glucose-1-phosphate uridylyltransferase YkuD_2 PF13645.1 EGC32579.1 - 0.12 11.6 1.6 0.14 11.3 1.1 1.2 1 0 0 1 1 1 0 L,D-transpeptidase catalytic domain CENP-X PF09415.5 EGC32580.1 - 1.2e-10 41.0 0.0 1.4e-10 40.8 0.0 1.0 1 0 0 1 1 1 1 CENP-S associating Centromere protein X NmrA PF05368.8 EGC32581.1 - 2.1e-53 180.9 0.0 2.6e-53 180.6 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC32581.1 - 3.2e-10 40.3 0.0 5e-10 39.6 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC32581.1 - 0.0026 16.4 0.0 0.0044 15.7 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family DUF4073 PF13285.1 EGC32582.1 - 0.011 15.1 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4073) Plant_vir_prot PF01307.12 EGC32584.1 - 1.5 8.5 28.4 4.2 7.1 1.8 5.1 2 1 3 5 5 5 0 Plant viral movement protein LRRNT_2 PF08263.7 EGC32584.1 - 2.5 8.1 16.8 8.4 6.4 0.1 3.9 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain DUF2919 PF11143.3 EGC32584.1 - 3.7 7.3 15.2 0.68 9.7 6.2 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2919) EcsB PF05975.7 EGC32584.1 - 7.7 4.8 23.0 1.3 7.4 10.6 2.6 1 1 0 2 2 2 0 Bacterial ABC transporter protein EcsB NS3_envE PF02723.9 EGC32584.1 - 9.9 6.1 19.6 31 4.5 0.0 5.0 5 0 0 5 5 5 0 Non-structural protein NS3/Small envelope protein E HAUS4 PF14735.1 EGC32585.1 - 0.017 14.4 3.7 0.021 14.1 2.6 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 4 DUF603 PF04645.7 EGC32585.1 - 0.027 14.4 5.5 0.07 13.0 3.8 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF603 TPR_MLP1_2 PF07926.7 EGC32585.1 - 0.075 12.7 5.6 0.099 12.3 3.9 1.1 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGC32585.1 - 0.091 12.3 4.0 0.11 12.0 2.8 1.1 1 0 0 1 1 1 0 IncA protein UN_NPL4 PF11543.3 EGC32585.1 - 0.1 12.8 3.0 6.6 7.0 0.5 2.2 1 1 1 2 2 2 0 Nuclear pore localisation protein NPL4 DUF167 PF02594.11 EGC32585.1 - 0.11 12.4 0.4 4 7.4 0.1 2.9 1 1 1 2 2 2 0 Uncharacterised ACR, YggU family COG1872 LUC7 PF03194.10 EGC32585.1 - 0.13 11.7 1.6 0.15 11.6 1.1 1.1 1 0 0 1 1 1 0 LUC7 N_terminus Spc24 PF08286.6 EGC32585.1 - 0.24 11.0 8.4 0.21 11.3 1.8 2.0 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 Phage_GP20 PF06810.6 EGC32585.1 - 0.26 10.7 6.4 0.34 10.3 4.4 1.2 1 0 0 1 1 1 0 Phage minor structural protein GP20 DUF972 PF06156.8 EGC32585.1 - 0.28 11.5 8.3 6.4 7.1 5.8 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF972) COMP PF11598.3 EGC32585.1 - 0.3 11.1 3.1 2 8.5 0.2 2.6 3 0 0 3 3 3 0 Cartilage oligomeric matrix protein DUF947 PF06102.7 EGC32585.1 - 0.31 10.8 4.7 0.39 10.5 3.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF947) Snapin_Pallidin PF14712.1 EGC32585.1 - 0.32 11.3 6.4 0.33 11.2 2.9 1.8 1 1 1 2 2 2 0 Snapin/Pallidin DivIC PF04977.10 EGC32585.1 - 0.37 10.3 4.5 0.14 11.6 0.6 2.0 2 1 0 2 2 2 0 Septum formation initiator Med11 PF10280.4 EGC32585.1 - 1 9.4 5.0 2.4 8.2 3.5 1.6 1 1 0 1 1 1 0 Mediator complex protein bZIP_1 PF00170.16 EGC32585.1 - 3.7 7.5 10.1 3.4 7.6 0.6 2.5 2 1 0 2 2 2 0 bZIP transcription factor RINT1_TIP1 PF04437.8 EGC32587.1 - 1.1e-64 218.8 28.9 6.4e-49 166.8 11.0 3.7 3 1 1 4 4 4 2 RINT-1 / TIP-1 family Tim54 PF11711.3 EGC32587.1 - 5.9 5.3 20.0 0.047 12.2 2.9 2.5 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Claudin_2 PF13903.1 EGC32588.1 - 1.7 8.3 11.5 3.3 7.3 7.0 2.1 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Acyl-CoA_dh_1 PF00441.19 EGC32589.1 - 3.5e-25 88.8 0.0 7.5e-25 87.7 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_2 PF08028.6 EGC32589.1 - 2.1e-05 24.7 0.0 4e-05 23.8 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGC32589.1 - 0.019 14.4 0.1 0.056 12.9 0.1 1.8 1 1 0 1 1 1 0 Acyl-CoA dehydrogenase, middle domain UBX PF00789.15 EGC32590.1 - 9.6e-12 44.8 0.0 3.6e-11 42.9 0.0 2.0 2 0 0 2 2 2 1 UBX domain UBA_4 PF14555.1 EGC32590.1 - 3.5e-11 42.4 1.7 5.1e-11 41.9 0.5 1.8 2 0 0 2 2 2 1 UBA-like domain Thioredoxin_7 PF13899.1 EGC32590.1 - 4.9e-10 39.3 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC32590.1 - 0.0044 17.2 0.1 0.0044 17.2 0.1 2.9 3 2 0 3 3 3 1 Thioredoxin-like domain Arrestin_C PF02752.17 EGC32590.1 - 0.12 12.4 3.9 0.85 9.7 2.7 2.2 1 1 0 1 1 1 0 Arrestin (or S-antigen), C-terminal domain TT_ORF2 PF02957.10 EGC32590.1 - 0.43 11.2 8.1 0.93 10.2 5.6 1.5 1 0 0 1 1 1 0 TT viral ORF2 DUF2457 PF10446.4 EGC32590.1 - 0.6 8.7 17.8 0.95 8.1 12.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF1510 PF07423.6 EGC32591.1 - 0.0034 16.7 3.2 0.0034 16.7 2.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) NOA36 PF06524.7 EGC32591.1 - 0.061 12.5 4.1 0.064 12.5 2.8 1.0 1 0 0 1 1 1 0 NOA36 protein DUF2126 PF09899.4 EGC32591.1 - 0.075 11.0 0.7 0.083 10.9 0.5 1.0 1 0 0 1 1 1 0 Putative amidoligase enzyme (DUF2126) Pox_Ag35 PF03286.9 EGC32591.1 - 7 6.1 9.6 7.8 5.9 6.6 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein RNA_pol_Rpc4 PF05132.9 EGC32591.1 - 8.7 6.3 7.4 11 6.0 5.1 1.1 1 0 0 1 1 1 0 RNA polymerase III RPC4 DUF4337 PF14235.1 EGC32592.1 - 0.56 10.0 2.6 1.2 8.9 1.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) Cofilin_ADF PF00241.15 EGC32593.1 - 4.2e-12 46.0 0.6 6.8e-12 45.3 0.4 1.4 1 1 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Imm23 PF15593.1 EGC32593.1 - 0.11 12.6 1.1 0.16 12.2 0.8 1.1 1 0 0 1 1 1 0 Immunity protein 23 DUF3647 PF12363.3 EGC32594.1 - 0.016 15.2 1.8 0.019 15.0 0.3 1.8 2 0 0 2 2 2 0 Phage protein Mit_KHE1 PF10173.4 EGC32594.1 - 0.41 10.4 2.3 2.3 8.0 0.5 2.2 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related PyrI PF01948.13 EGC32596.1 - 0.44 10.6 4.6 0.083 12.9 0.8 1.6 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Surf_Ag_VNR PF07244.10 EGC32597.1 - 0.043 14.2 1.1 0.1 13.0 0.8 1.6 1 1 0 1 1 1 0 Surface antigen variable number repeat FPL PF09758.4 EGC32597.1 - 0.047 13.4 1.2 0.075 12.7 0.8 1.3 1 0 0 1 1 1 0 Uncharacterised conserved protein RhoGAP PF00620.22 EGC32598.1 - 0.01 15.4 0.0 0.021 14.4 0.0 1.6 1 0 0 1 1 1 0 RhoGAP domain KCl_Cotrans_1 PF03522.10 EGC32598.1 - 0.05 13.1 0.3 0.17 11.4 0.2 1.9 1 0 0 1 1 1 0 K-Cl Co-transporter type 1 (KCC1) DUF677 PF05055.7 EGC32599.1 - 0.023 13.3 0.1 0.028 13.1 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF677) DUF566 PF04484.7 EGC32600.1 - 0.51 9.8 8.5 0.66 9.4 5.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) SprA-related PF12118.3 EGC32600.1 - 2.8 7.1 9.6 3.7 6.7 6.6 1.2 1 0 0 1 1 1 0 SprA-related family DUF1772 PF08592.6 EGC32602.1 - 4.9e-16 58.7 0.0 8.4e-16 57.9 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) DUF202 PF02656.10 EGC32602.1 - 0.076 13.2 2.8 0.14 12.4 0.0 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF202) ERG2_Sigma1R PF04622.7 EGC32603.1 - 9.3e-44 149.2 0.0 1.1e-43 148.9 0.0 1.0 1 0 0 1 1 1 1 ERG2 and Sigma1 receptor like protein NS3_envE PF02723.9 EGC32603.1 - 0.0061 16.4 0.5 0.012 15.5 0.3 1.5 1 0 0 1 1 1 1 Non-structural protein NS3/Small envelope protein E NDUF_B12 PF08122.7 EGC32604.1 - 4.8 7.0 8.7 13 5.6 6.0 1.7 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase B12 subunit family F-box-like PF12937.2 EGC32605.1 - 0.0014 18.3 2.9 0.0038 16.9 0.3 2.5 2 0 0 2 2 2 1 F-box-like LRR_6 PF13516.1 EGC32605.1 - 0.83 9.9 30.6 0.25 11.4 0.4 8.1 8 0 0 8 8 8 0 Leucine Rich repeat Ndr PF03096.9 EGC32606.1 - 9.7e-74 247.3 0.0 1.2e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Ndr family Abhydrolase_6 PF12697.2 EGC32606.1 - 9.8e-14 51.7 0.0 1.2e-13 51.4 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC32606.1 - 1.7e-06 27.7 0.0 2.2e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold EIAV_GP90 PF00971.13 EGC32606.1 - 0.0061 15.0 0.0 0.0084 14.6 0.0 1.1 1 0 0 1 1 1 1 EIAV coat protein, gp90 AAA PF00004.24 EGC32607.1 - 6.3e-41 139.6 0.0 1.1e-40 138.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC32607.1 - 9.4e-08 32.2 0.2 0.00041 20.4 0.0 2.6 2 1 1 3 3 2 2 AAA domain AAA_2 PF07724.9 EGC32607.1 - 1.1e-05 25.3 0.0 2.8e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGC32607.1 - 1.7e-05 23.8 0.1 4.8e-05 22.4 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_5 PF07728.9 EGC32607.1 - 3.6e-05 23.5 0.8 0.0002 21.0 0.2 2.4 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC32607.1 - 0.00019 21.4 0.0 0.00066 19.7 0.0 1.8 1 1 0 1 1 1 1 AAA ATPase domain NB-ARC PF00931.17 EGC32607.1 - 0.0002 20.3 0.0 0.082 11.7 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain RuvB_N PF05496.7 EGC32607.1 - 0.00093 18.3 0.0 0.0019 17.3 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_25 PF13481.1 EGC32607.1 - 0.0015 17.9 0.7 0.19 11.1 0.1 2.3 1 1 1 2 2 2 1 AAA domain Sigma54_activat PF00158.21 EGC32607.1 - 0.0047 16.4 0.1 0.11 11.9 0.0 2.3 2 0 0 2 2 2 1 Sigma-54 interaction domain KaiC PF06745.8 EGC32607.1 - 0.0053 15.9 0.1 0.21 10.7 0.1 2.3 1 1 1 2 2 2 1 KaiC IstB_IS21 PF01695.12 EGC32607.1 - 0.0054 16.1 0.0 0.01 15.2 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGC32607.1 - 0.0098 15.6 0.2 0.022 14.4 0.1 1.5 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGC32607.1 - 0.012 15.7 0.0 0.038 14.1 0.0 1.9 1 0 0 1 1 1 0 RNA helicase AAA_18 PF13238.1 EGC32607.1 - 0.013 15.7 0.2 0.072 13.3 0.0 2.2 2 0 0 2 2 2 0 AAA domain TIP49 PF06068.8 EGC32607.1 - 0.017 13.8 0.0 0.032 12.9 0.0 1.4 1 0 0 1 1 1 0 TIP49 C-terminus NACHT PF05729.7 EGC32607.1 - 0.019 14.6 0.1 0.12 12.0 0.0 2.1 1 1 0 2 2 2 0 NACHT domain AAA_3 PF07726.6 EGC32607.1 - 0.02 14.5 0.0 0.057 13.0 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Zeta_toxin PF06414.7 EGC32607.1 - 0.023 13.7 0.0 0.041 12.9 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGC32607.1 - 0.03 13.9 0.1 0.089 12.3 0.1 1.7 1 0 0 1 1 1 0 AAA domain PhoH PF02562.11 EGC32607.1 - 0.032 13.4 0.2 0.14 11.3 0.0 2.0 2 0 0 2 2 2 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EGC32607.1 - 0.033 14.2 0.0 0.1 12.6 0.0 1.9 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_17 PF13207.1 EGC32607.1 - 0.033 15.0 0.4 0.092 13.5 0.1 2.0 2 1 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EGC32607.1 - 0.034 14.0 0.0 0.082 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGC32607.1 - 0.047 13.6 0.0 0.092 12.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGC32607.1 - 0.047 13.5 0.0 0.09 12.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGC32607.1 - 0.07 12.2 0.0 0.13 11.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI DUF2075 PF09848.4 EGC32607.1 - 0.098 11.6 0.0 0.16 10.9 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) MMS1_N PF10433.4 EGC32608.1 - 7.2e-30 103.5 12.8 7.2e-30 103.5 8.9 2.5 2 1 0 2 2 2 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Ribosomal_L4 PF00573.17 EGC32608.1 - 0.86 8.9 3.9 1.2 8.4 0.2 2.8 3 0 0 3 3 3 0 Ribosomal protein L4/L1 family FNIP PF05725.7 EGC32609.1 - 1.8e-25 88.5 58.7 1e-09 38.1 0.5 10.7 7 3 3 10 10 10 8 FNIP Repeat ketoacyl-synt PF00109.21 EGC32610.1 - 7.2e-60 202.5 0.0 1.1e-59 202.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32610.1 - 9.6e-54 182.8 0.0 2.1e-53 181.7 0.0 1.6 2 0 0 2 2 2 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC32610.1 - 2.5e-33 115.0 0.0 9e-33 113.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC32610.1 - 1.4e-27 95.9 0.0 2.4e-27 95.1 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGC32610.1 - 6.2e-23 81.3 0.0 9.3e-23 80.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGC32610.1 - 4.3e-20 72.1 0.0 1.6e-19 70.2 0.0 1.9 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC32610.1 - 1.7e-19 70.0 3.9 1.9e-18 66.7 0.0 3.2 2 0 0 2 2 2 1 Methyltransferase domain adh_short PF00106.20 EGC32610.1 - 5.6e-14 52.3 0.0 2.6e-13 50.2 0.0 2.1 2 0 0 2 2 2 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC32610.1 - 7.8e-10 38.7 0.0 2e-09 37.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC32610.1 - 2.5e-08 34.2 0.0 6.9e-08 32.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGC32610.1 - 3e-05 23.7 0.0 0.00012 21.8 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain Methyltransf_18 PF12847.2 EGC32610.1 - 0.00052 20.5 0.0 0.0026 18.3 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32610.1 - 0.00062 18.8 0.0 0.0012 17.8 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_zinc_N_2 PF13602.1 EGC32610.1 - 0.0019 19.0 0.0 0.0044 17.9 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PALP PF00291.20 EGC32610.1 - 2.7 7.1 0.0 14 4.8 0.0 1.9 2 0 0 2 2 2 0 Pyridoxal-phosphate dependent enzyme SK_channel PF03530.9 EGC32611.1 - 0.0006 19.6 1.5 0.0006 19.6 1.0 2.9 3 0 0 3 3 3 1 Calcium-activated SK potassium channel Ion_trans_2 PF07885.11 EGC32611.1 - 0.0046 16.6 5.6 0.0046 16.6 3.9 2.2 2 1 0 2 2 2 1 Ion channel Lig_chan PF00060.21 EGC32611.1 - 0.063 13.0 2.9 0.041 13.6 0.2 2.1 2 1 0 2 2 2 0 Ligand-gated ion channel DUF2838 PF10998.3 EGC32611.1 - 1.8 8.5 12.0 0.024 14.5 2.2 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2838) Cupin_8 PF13621.1 EGC32612.1 - 8.4e-20 71.3 0.0 8.4e-20 71.3 0.0 3.0 3 1 1 4 4 4 1 Cupin-like domain JmjC PF02373.17 EGC32612.1 - 3.3e-16 59.5 2.2 7.3e-16 58.4 0.0 2.8 2 0 0 2 2 2 1 JmjC domain, hydroxylase APH PF01636.18 EGC32612.1 - 0.0052 16.5 0.0 3 7.5 0.0 2.3 2 0 0 2 2 2 2 Phosphotransferase enzyme family VWA_2 PF13519.1 EGC32613.1 - 9.5e-16 58.3 0.0 2e-15 57.3 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain PH PF00169.24 EGC32613.1 - 1.3e-10 41.3 1.1 1.3e-10 41.3 0.8 2.9 2 0 0 2 2 2 1 PH domain ubiquitin PF00240.18 EGC32613.1 - 2e-06 27.0 0.2 7.9e-06 25.1 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin family Mcp5_PH PF12814.2 EGC32613.1 - 1.5e-05 24.9 0.3 7e-05 22.7 0.2 2.2 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 EGC32613.1 - 0.00075 19.7 2.7 0.00075 19.7 1.9 4.0 4 2 1 5 5 5 1 Pleckstrin homology domain PH_8 PF15409.1 EGC32613.1 - 0.008 16.2 0.7 0.008 16.2 0.5 3.1 4 0 0 4 4 4 1 Pleckstrin homology domain Glyco_hydro_25 PF01183.15 EGC32614.1 - 1.4e-09 38.0 0.0 1.6e-09 37.8 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 Pkinase PF00069.20 EGC32615.1 - 7.6e-61 205.5 0.9 8.3e-61 205.4 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32615.1 - 3.4e-39 134.4 0.0 1.4e-35 122.6 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC32615.1 - 3.8e-06 26.0 0.0 1.4e-05 24.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC32615.1 - 0.064 12.9 0.0 0.21 11.2 0.0 1.5 1 1 1 2 2 2 0 Phosphotransferase enzyme family Thioredox_DsbH PF03190.10 EGC32616.1 - 1.5e-67 226.3 0.1 4.1e-67 224.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF255 Thioredoxin_7 PF13899.1 EGC32616.1 - 5.1e-08 32.8 0.0 1.2e-07 31.5 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like C5-epim_C PF06662.8 EGC32616.1 - 5.8e-06 25.7 4.8 0.0014 17.9 0.0 3.8 3 2 0 3 3 3 2 D-glucuronyl C5-epimerase C-terminus Thioredoxin_2 PF13098.1 EGC32616.1 - 0.016 15.4 0.1 0.075 13.2 0.0 2.2 2 0 0 2 2 2 0 Thioredoxin-like domain Glyco_hydro_76 PF03663.9 EGC32616.1 - 0.032 13.6 0.9 0.29 10.4 0.0 2.3 1 1 1 2 2 2 0 Glycosyl hydrolase family 76 RNA_pol_L_2 PF13656.1 EGC32616.1 - 0.082 12.3 1.1 0.95 8.9 0.1 2.6 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain DUF1084 PF06454.6 EGC32617.1 - 1.9e-08 33.7 29.7 5.2e-08 32.2 20.6 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) zf-RING_2 PF13639.1 EGC32619.1 - 2.5e-11 43.1 9.4 4.3e-11 42.4 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC32619.1 - 1.5e-08 34.1 7.5 2.3e-08 33.5 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC32619.1 - 4.3e-08 33.1 5.2 8.7e-08 32.1 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC32619.1 - 2.7e-07 30.1 11.5 4.9e-07 29.2 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32619.1 - 1e-06 28.6 10.2 1.8e-06 27.8 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32619.1 - 1.1e-05 25.1 9.4 1.8e-05 24.3 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain IBR PF01485.16 EGC32619.1 - 0.00099 18.9 7.8 0.0028 17.4 5.4 1.8 1 0 0 1 1 1 1 IBR domain zf-RING_4 PF14570.1 EGC32619.1 - 0.0011 18.5 10.6 0.0021 17.6 7.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC32619.1 - 0.0084 15.8 2.3 0.044 13.4 1.6 2.4 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EGC32619.1 - 0.0084 15.6 4.8 0.017 14.6 3.3 1.5 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EGC32619.1 - 0.01 15.6 11.1 0.024 14.5 6.6 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EGC32619.1 - 0.032 14.0 7.4 0.062 13.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-Apc11 PF12861.2 EGC32619.1 - 0.039 13.8 4.6 0.082 12.7 3.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC32619.1 - 0.13 11.8 7.6 0.26 10.8 5.3 1.6 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-UDP PF14569.1 EGC32619.1 - 0.21 11.3 2.8 0.42 10.3 1.9 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-P11 PF03854.9 EGC32619.1 - 3 7.4 7.1 8 6.0 4.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger Plant_vir_prot PF01307.12 EGC32621.1 - 0.0028 17.3 20.5 1.3 8.7 0.3 5.2 2 2 3 5 5 5 3 Plant viral movement protein PROL5-SMR PF15621.1 EGC32621.1 - 0.024 15.0 4.5 0.14 12.5 2.1 2.4 2 0 0 2 2 2 0 Proline-rich submaxillary gland androgen-regulated family DUF3357 PF11837.3 EGC32621.1 - 0.035 13.9 14.7 3.7 7.4 0.1 4.8 1 1 2 5 5 5 0 Domain of unknown function (DUF3357) H_PPase PF03030.11 EGC32621.1 - 0.1 10.8 0.5 0.16 10.1 0.3 1.3 1 0 0 1 1 1 0 Inorganic H+ pyrophosphatase MARVEL PF01284.18 EGC32621.1 - 0.21 11.3 7.8 6.5 6.5 5.8 2.5 1 1 0 1 1 1 0 Membrane-associating domain DUF21 PF01595.15 EGC32621.1 - 0.22 10.7 7.4 0.03 13.5 1.0 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF21 VIT1 PF01988.14 EGC32621.1 - 0.24 10.8 10.1 0.2 11.0 0.2 3.1 2 2 1 3 3 3 0 VIT family Virul_fac_BrkB PF03631.10 EGC32621.1 - 0.35 10.1 6.3 0.079 12.3 0.4 2.1 2 1 0 2 2 2 0 Virulence factor BrkB DUF3379 PF11859.3 EGC32621.1 - 0.54 9.3 3.1 1.5 7.9 0.7 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF3379) EI24 PF07264.6 EGC32621.1 - 0.97 8.8 7.4 0.17 11.3 0.6 2.8 1 1 2 3 3 3 0 Etoposide-induced protein 2.4 (EI24) RNase_H2-Ydr279 PF09468.5 EGC32622.1 - 3.4e-46 157.8 11.1 3.4e-46 157.8 7.7 1.9 2 0 0 2 2 2 1 Ydr279p protein family (RNase H2 complex component) Siah-Interact_N PF09032.6 EGC32622.1 - 2.2 8.3 6.4 15 5.7 0.8 2.5 2 0 0 2 2 2 0 Siah interacting protein, N terminal F-box-like PF12937.2 EGC32623.1 - 0.038 13.7 0.6 0.9 9.3 0.0 3.0 3 0 0 3 3 3 0 F-box-like SSP160 PF06933.6 EGC32623.1 - 2.1 6.2 11.4 2.9 5.7 7.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 PMBR PF09373.5 EGC32623.1 - 3.7 7.6 11.7 2.7 8.0 0.5 4.1 4 0 0 4 4 4 0 Pseudomurein-binding repeat Yip1 PF04893.12 EGC32624.1 - 0.0024 17.3 0.0 0.084 12.3 0.0 3.1 4 1 0 4 4 4 1 Yip1 domain Glycophorin_A PF01102.13 EGC32624.1 - 0.0028 17.3 0.0 0.0028 17.3 0.0 4.7 5 0 0 5 5 5 1 Glycophorin A Adaptin_binding PF10199.4 EGC32624.1 - 0.024 14.9 0.5 0.024 14.9 0.3 5.0 2 1 0 2 2 2 0 Alpha and gamma adaptin binding protein p34 SprA-related PF12118.3 EGC32624.1 - 0.034 13.4 0.2 0.034 13.4 0.1 3.7 2 1 1 3 3 3 0 SprA-related family DUF4064 PF13273.1 EGC32624.1 - 0.089 12.8 0.2 0.089 12.8 0.1 6.8 5 2 2 7 7 7 0 Protein of unknown function (DUF4064) ECH_C PF13766.1 EGC32625.1 - 1.9e-21 76.3 0.0 3.4e-21 75.5 0.0 1.4 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGC32625.1 - 4.6e-15 55.4 0.0 9.1e-15 54.4 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3522 PF12036.3 EGC32626.1 - 6.4e-51 172.7 9.4 8e-51 172.4 6.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3522) HlyIII PF03006.15 EGC32626.1 - 0.0031 16.9 13.2 0.025 14.0 9.2 2.1 1 1 0 1 1 1 1 Haemolysin-III related Ceramidase PF05875.7 EGC32626.1 - 0.03 13.4 0.2 0.03 13.4 0.1 2.7 2 1 0 2 2 2 0 Ceramidase FNIP PF05725.7 EGC32628.1 - 2.8e-197 638.5 94.2 3.6e-15 55.6 0.1 14.0 2 2 12 18 18 18 18 FNIP Repeat Phage_min_tail PF05939.8 EGC32628.1 - 5.1e-05 23.1 0.0 20 5.1 0.0 7.2 6 4 5 11 11 11 1 Phage minor tail protein DUF3215 PF11503.3 EGC32628.1 - 0.072 12.7 0.1 1.3 8.6 0.0 3.2 2 1 0 2 2 2 0 Protein of unknown function (DUF3215) Terminase_1 PF03354.10 EGC32628.1 - 0.22 9.8 0.1 0.33 9.3 0.1 1.1 1 0 0 1 1 1 0 Phage Terminase DUF1769 PF08588.5 EGC32628.1 - 0.5 10.3 59.7 4.2 7.3 0.2 15.5 5 4 15 20 20 20 0 Protein of unknown function (DUF1769) PIF1 PF05970.9 EGC32628.1 - 1.9 7.3 6.6 39 3.0 0.0 4.8 5 1 1 6 6 6 0 PIF1-like helicase Bclx_interact PF08945.5 EGC32628.1 - 2.1 7.9 3.2 2.4e+02 1.3 0.0 4.4 3 0 0 3 3 3 0 Bcl-x interacting, BH3 domain FNIP PF05725.7 EGC32629.1 - 4.2e-192 621.9 79.5 1.6e-16 59.9 0.0 15.5 9 3 5 17 17 17 17 FNIP Repeat DUF1769 PF08588.5 EGC32629.1 - 0.29 11.1 57.1 4.5 7.2 0.0 16.5 6 4 16 22 22 22 0 Protein of unknown function (DUF1769) Bclx_interact PF08945.5 EGC32629.1 - 0.36 10.3 1.7 2.2e+02 1.4 0.0 5.0 6 0 0 6 6 6 0 Bcl-x interacting, BH3 domain Keratin_matx PF04579.7 EGC32629.1 - 1.1 9.5 5.7 3.5 7.9 1.3 3.6 1 1 2 3 3 3 0 Keratin, high-sulphur matrix protein PIF1 PF05970.9 EGC32629.1 - 5.5 5.8 4.4 49 2.7 0.0 3.5 4 0 0 4 4 4 0 PIF1-like helicase Peptidase_S8 PF00082.17 EGC32631.1 - 5.3e-40 137.3 0.8 7.7e-40 136.8 0.6 1.2 1 0 0 1 1 1 1 Subtilase family C9orf72-like PF15019.1 EGC32631.1 - 0.017 14.3 1.1 0.026 13.7 0.7 1.2 1 0 0 1 1 1 0 C9orf72-like protein family EGF_2 PF07974.8 EGC32631.1 - 0.085 13.0 15.2 0.19 11.9 10.5 1.6 1 0 0 1 1 1 0 EGF-like domain DUF2348 PF09807.4 EGC32632.1 - 9.1e-26 90.4 0.0 2.5e-12 46.4 0.0 2.6 2 1 0 2 2 2 2 Uncharacterized conserved protein (DUF2348) Elong_Iki1 PF10483.4 EGC32632.1 - 1.5e-05 24.4 0.9 0.0027 17.1 0.3 2.2 2 0 0 2 2 2 2 Elongator subunit Iki1 GpcrRhopsn4 PF10192.4 EGC32632.1 - 0.029 13.5 0.1 0.066 12.3 0.1 1.5 1 0 0 1 1 1 0 Rhodopsin-like GPCR transmembrane domain Coat_F PF07875.7 EGC32632.1 - 0.059 13.5 0.1 0.15 12.2 0.0 1.6 1 0 0 1 1 1 0 Coat F domain SGS PF05002.10 EGC32632.1 - 0.12 12.1 0.0 0.32 10.7 0.0 1.7 1 0 0 1 1 1 0 SGS domain RhoGAP PF00620.22 EGC32633.1 - 2.7e-05 23.8 0.5 5.6e-05 22.7 0.3 1.5 1 0 0 1 1 1 1 RhoGAP domain RA PF00788.18 EGC32633.1 - 0.0026 18.2 0.0 0.0054 17.1 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain AAA_12 PF13087.1 EGC32633.1 - 0.12 11.7 3.8 0.17 11.2 2.4 1.5 1 1 0 1 1 1 0 AAA domain Pol_alpha_B_N PF08418.5 EGC32634.1 - 1.9 7.9 10.2 2.3 7.6 7.1 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Afi1 PF07792.7 EGC32635.1 - 7.8e-47 158.9 11.2 3.3e-32 111.4 0.1 2.8 3 0 0 3 3 3 2 Docking domain of Afi1 for Arf3 in vesicle trafficking SPA PF08616.5 EGC32635.1 - 4.2e-33 113.4 0.1 3.3e-32 110.5 0.0 2.5 3 0 0 3 3 3 1 Stabilization of polarity axis Avl9 PF09794.4 EGC32635.1 - 7.2e-10 37.8 5.3 0.11 10.9 0.0 4.6 2 2 2 4 4 4 3 Transport protein Avl9 DUF2347 PF09804.4 EGC32635.1 - 9.3e-05 21.8 8.0 0.0011 18.2 0.0 4.0 3 2 1 4 4 4 2 Uncharacterized conserved protein (DUF2347) DUF3439 PF11921.3 EGC32635.1 - 0.19 11.4 6.4 0.6 9.8 4.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2894 PF11445.3 EGC32635.1 - 0.79 9.9 0.0 0.79 9.9 0.0 3.3 3 1 0 4 4 4 0 Protein of unknown function (DUF2894) Menin PF05053.8 EGC32635.1 - 3.7 5.6 12.3 2.1 6.4 2.3 2.3 2 0 0 2 2 2 0 Menin Glycolytic PF00274.14 EGC32636.1 - 3.7e-162 538.6 0.0 4.2e-162 538.4 0.0 1.0 1 0 0 1 1 1 1 Fructose-bisphosphate aldolase class-I DUF1537 PF07005.6 EGC32636.1 - 0.024 14.3 0.0 0.038 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF1537 WD40 PF00400.27 EGC32637.1 - 9e-32 107.8 19.8 6.7e-10 38.4 0.0 6.1 6 0 0 6 6 6 5 WD domain, G-beta repeat PD40 PF07676.7 EGC32637.1 - 0.0058 16.2 2.2 4.2 7.1 0.0 3.4 3 0 0 3 3 3 2 WD40-like Beta Propeller Repeat Crystall_3 PF08964.5 EGC32638.1 - 2.4e-25 88.0 0.0 4.9e-25 87.0 0.0 1.5 1 0 0 1 1 1 1 Beta/Gamma crystallin Membrane_bind PF14564.1 EGC32638.1 - 1.9e-21 76.2 0.1 3e-21 75.6 0.1 1.3 1 0 0 1 1 1 1 Membrane binding VRR_NUC PF08774.6 EGC32639.1 - 0.013 15.5 0.4 0.036 14.0 0.0 2.0 2 0 0 2 2 2 0 VRR-NUC domain MA3 PF02847.12 EGC32639.1 - 0.024 14.3 0.6 0.083 12.5 0.1 1.9 2 0 0 2 2 2 0 MA3 domain HJURP_C PF12347.3 EGC32640.1 - 0.011 15.2 0.8 0.011 15.2 0.5 2.3 2 1 0 2 2 2 0 Holliday junction regulator protein family C-terminal repeat RGS-like PF09128.6 EGC32640.1 - 0.3 10.5 8.1 0.45 9.9 5.6 1.3 1 0 0 1 1 1 0 Regulator of G protein signalling-like domain HU-DNA_bdg PF14848.1 EGC32640.1 - 0.54 9.9 9.6 0.13 11.9 4.0 2.0 2 1 0 2 2 2 0 DNA-binding domain DUF4164 PF13747.1 EGC32640.1 - 0.96 9.6 6.2 1.4 9.0 1.8 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF4164) YojJ PF10372.4 EGC32640.1 - 3 7.7 10.5 7.5 6.5 0.2 3.6 1 1 2 3 3 3 0 Bacterial membrane-spanning protein N-terminus Myb_DNA-bind_3 PF12776.2 EGC32640.1 - 8.3 7.1 12.6 8.1 7.1 2.4 3.1 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain VIT1 PF01988.14 EGC32641.1 - 2.7e-59 200.2 1.2 3.2e-59 200.0 0.8 1.0 1 0 0 1 1 1 1 VIT family SDA1 PF05285.7 EGC32642.1 - 5.9 6.0 14.2 8.8 5.4 9.9 1.3 1 0 0 1 1 1 0 SDA1 LSM PF01423.17 EGC32643.1 - 2.6e-11 42.9 0.1 6.3e-11 41.6 0.0 1.7 1 0 0 1 1 1 1 LSM domain PAT1 PF09770.4 EGC32643.1 - 0.00069 17.9 8.9 0.00069 17.9 6.1 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DUF3439 PF11921.3 EGC32643.1 - 0.0047 16.6 2.5 0.0069 16.1 1.7 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Maf1 PF09174.5 EGC32643.1 - 0.17 11.6 4.1 0.3 10.9 2.9 1.4 1 1 0 1 1 1 0 Maf1 regulator vMSA PF00695.14 EGC32643.1 - 0.23 10.6 6.0 0.26 10.4 4.1 1.2 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Mucin PF01456.12 EGC32643.1 - 0.84 9.4 14.8 1.2 8.9 10.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF605 PF04652.11 EGC32643.1 - 2.2 7.5 17.4 0.71 9.2 10.2 1.5 2 0 0 2 2 2 0 Vta1 like REC114-like PF15165.1 EGC32643.1 - 3 7.5 7.6 4.5 6.9 5.3 1.2 1 0 0 1 1 1 0 Meiotic recombination protein REC114-like Pap_E4 PF02711.9 EGC32643.1 - 3.1 8.6 16.9 5.4 7.8 11.7 1.4 1 0 0 1 1 1 0 E4 protein Lin-8 PF03353.10 EGC32643.1 - 5.7 6.1 12.9 2.1 7.5 6.7 1.8 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist Pex16 PF08610.5 EGC32643.1 - 8.1 5.3 9.3 14 4.6 6.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) NTP_transf_2 PF01909.18 EGC32644.1 - 7.7e-07 29.3 0.2 8.3e-06 26.0 0.0 2.8 2 0 0 2 2 2 1 Nucleotidyltransferase domain tRNA_NucTransf2 PF09249.6 EGC32644.1 - 0.00024 20.9 0.2 0.0016 18.3 0.0 2.5 2 0 0 2 2 2 1 tRNA nucleotidyltransferase, second domain OAS1_C PF10421.4 EGC32644.1 - 0.024 14.1 0.0 0.049 13.1 0.0 1.4 1 0 0 1 1 1 0 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus UPF0118 PF01594.11 EGC32644.1 - 7.1 5.5 10.5 1.1 8.2 0.5 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF20 Thg1 PF04446.7 EGC32645.1 - 1.5e-32 112.0 0.4 1.5e-32 112.0 0.3 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EGC32645.1 - 0.0019 17.9 4.1 0.035 13.8 2.8 2.5 1 1 0 1 1 1 1 Thg1 C terminal domain Cir_N PF10197.4 EGC32646.1 - 0.039 13.9 3.8 0.06 13.3 2.7 1.3 1 0 0 1 1 1 0 N-terminal domain of CBF1 interacting co-repressor CIR Ecm29 PF13001.2 EGC32647.1 - 5.8e-126 420.9 7.4 5.8e-126 420.9 5.1 3.1 3 0 0 3 3 3 1 Proteasome stabiliser Vac14_Fab1_bd PF12755.2 EGC32647.1 - 1.5e-10 41.3 5.8 0.011 16.1 0.0 8.5 8 1 1 9 9 9 3 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EGC32647.1 - 1.1e-09 38.4 0.0 0.67 10.2 0.0 7.6 7 1 0 7 7 7 3 HEAT repeats HEAT PF02985.17 EGC32647.1 - 8.1e-07 28.6 0.1 1.7 8.9 0.0 6.5 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EGC32647.1 - 0.005 17.3 0.0 8.2 7.0 0.0 5.5 6 0 0 6 6 6 1 HEAT-like repeat DUF4564 PF15169.1 EGC32650.1 - 6.4e-65 218.4 1.8 8.2e-65 218.0 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4564) Claudin_3 PF06653.6 EGC32650.1 - 0.035 13.8 0.0 0.044 13.5 0.0 1.2 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF4517 PF15006.1 EGC32650.1 - 0.049 13.4 0.1 0.097 12.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4517) zf-CSL PF05207.8 EGC32652.1 - 1.5e-05 24.3 1.0 3.1e-05 23.4 0.7 1.5 1 0 0 1 1 1 1 CSL zinc finger Phytoreo_Pns PF05451.6 EGC32652.1 - 0.17 10.4 1.7 0.2 10.2 1.2 1.1 1 0 0 1 1 1 0 Phytoreovirus nonstructural protein Pns10/11 PA26 PF04636.8 EGC32652.1 - 0.43 9.2 2.7 0.41 9.2 1.9 1.1 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) SAP PF02037.22 EGC32653.1 - 0.00063 19.1 0.7 0.039 13.4 0.3 2.5 2 0 0 2 2 2 1 SAP domain DUF2981 PF11200.3 EGC32653.1 - 0.11 11.5 10.2 0.2 10.6 7.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2981) Neur_chan_memb PF02932.11 EGC32653.1 - 4.7 7.0 15.7 1e+03 -0.6 10.9 2.5 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region ubiquitin PF00240.18 EGC32654.1 - 3e-102 334.0 15.4 9.7e-34 114.6 0.6 3.0 3 0 0 3 3 3 3 Ubiquitin family Rad60-SLD PF11976.3 EGC32654.1 - 3.8e-58 193.0 12.9 8e-19 67.1 0.4 3.0 3 0 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC32654.1 - 1.5e-18 66.7 6.2 0.00013 22.1 0.1 4.6 3 3 0 3 3 3 3 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGC32654.1 - 3.5e-14 52.8 0.1 0.0045 16.6 0.0 3.0 3 0 0 3 3 3 3 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGC32654.1 - 3.2e-10 39.8 0.8 0.13 12.1 0.0 3.8 3 3 0 3 3 3 3 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC32654.1 - 1.2e-09 38.2 0.3 0.18 12.0 0.0 3.2 1 1 2 3 3 3 3 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGC32654.1 - 7.1e-08 32.4 0.0 1 9.4 0.0 3.7 3 0 0 3 3 3 3 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EGC32654.1 - 1.2e-05 25.1 1.8 2.8 7.9 0.0 3.2 3 0 0 3 3 3 3 GLUT4 regulating protein TUG Big_3_3 PF13750.1 EGC32654.1 - 0.00015 21.1 0.0 7.9 5.8 0.0 3.2 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) Corona_NS2A PF05213.7 EGC32654.1 - 0.00056 19.2 0.0 9.5 5.4 0.0 3.0 1 1 0 3 3 3 0 Coronavirus NS2A protein Methyltrans_RNA PF04452.9 EGC32654.1 - 0.00067 18.8 0.2 1 8.4 0.0 2.3 2 0 0 2 2 2 2 RNA methyltransferase IGR PF09597.5 EGC32654.1 - 0.00096 19.0 0.0 22 5.0 0.0 3.4 3 0 0 3 3 3 0 IGR protein motif Plexin_cytopl PF08337.7 EGC32654.1 - 0.0013 17.1 5.6 2.7 6.1 0.1 4.5 4 2 0 4 4 4 2 Plexin cytoplasmic RasGAP domain DUF3435 PF11917.3 EGC32654.1 - 0.0047 15.7 0.2 14 4.2 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3435) FlgD_ig PF13860.1 EGC32654.1 - 0.0061 16.2 1.8 25 4.6 0.0 3.3 3 0 0 3 3 3 0 FlgD Ig-like domain DUF3642 PF12182.3 EGC32654.1 - 0.0086 16.4 3.7 24 5.4 0.1 3.5 3 0 0 3 3 3 0 Bacterial lipoprotein GABP-alpha PF11620.3 EGC32654.1 - 0.023 14.6 1.7 37 4.3 0.0 3.0 3 0 0 3 3 3 0 GA-binding protein alpha chain Ras_bdg_2 PF14847.1 EGC32654.1 - 0.027 14.3 1.0 55 3.7 0.0 3.4 3 0 0 3 3 3 0 Ras-binding domain of Byr2 ACT_4 PF13291.1 EGC32654.1 - 0.058 13.7 0.1 1.1e+02 3.2 0.0 3.2 3 0 0 3 3 3 0 ACT domain EMG1 PF03587.9 EGC32654.1 - 0.076 12.2 0.9 17 4.6 0.0 2.9 3 0 0 3 3 3 0 EMG1/NEP1 methyltransferase DUF3781 PF12636.2 EGC32654.1 - 0.14 12.1 2.2 76 3.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3781) DUF39 PF01837.11 EGC32654.1 - 0.53 8.8 3.6 11 4.5 0.0 2.6 3 0 0 3 3 3 0 Domain of unknown function DUF39 FERM_N PF09379.5 EGC32654.1 - 1.2 9.1 6.9 92 3.1 0.1 4.6 3 3 0 3 3 3 0 FERM N-terminal domain DAP_epimerase PF01678.14 EGC32655.1 - 1.7e-38 131.2 2.8 5.4e-21 74.7 0.1 2.7 2 1 0 2 2 2 2 Diaminopimelate epimerase DWNN PF08783.6 EGC32655.1 - 0.038 13.9 0.1 0.086 12.7 0.1 1.6 1 0 0 1 1 1 0 DWNN domain DUF1242 PF06842.7 EGC32656.1 - 8.7e-16 57.1 1.2 1.4e-15 56.5 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1242) DUF872 PF05915.7 EGC32657.1 - 0.33 10.8 2.1 0.36 10.7 0.7 1.6 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF2781 PF10914.3 EGC32657.1 - 0.48 10.2 4.9 0.77 9.5 3.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF2781) Peptidase_U4 PF03419.8 EGC32657.1 - 0.66 8.9 3.4 0.87 8.6 2.3 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA Peptidase_U4 PF03419.8 EGC32658.1 - 0.65 9.0 3.0 0.9 8.5 2.1 1.1 1 0 0 1 1 1 0 Sporulation factor SpoIIGA DUF872 PF05915.7 EGC32658.1 - 1.2 9.0 4.2 0.55 10.1 0.6 2.0 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Rpn3_C PF08375.6 EGC32659.1 - 1.6e-21 76.4 1.3 3.5e-21 75.3 0.9 1.6 1 0 0 1 1 1 1 Proteasome regulatory subunit C-terminal PCI PF01399.22 EGC32659.1 - 5e-19 68.5 4.5 1.1e-18 67.4 0.0 3.0 2 1 0 2 2 2 1 PCI domain PCI_Csn8 PF10075.4 EGC32659.1 - 1.6e-06 27.9 2.4 6.9e-06 25.8 0.3 2.8 2 1 0 2 2 2 1 COP9 signalosome, subunit CSN8 TPR_2 PF07719.12 EGC32659.1 - 0.09 12.7 0.5 0.25 11.3 0.3 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32659.1 - 0.32 10.9 3.7 9.2 6.2 0.5 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat DUF885 PF05960.6 EGC32660.1 - 1.7e-140 469.8 0.0 2e-140 469.6 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF885) AAA PF00004.24 EGC32661.1 - 6.2e-99 327.3 0.0 1.2e-48 164.6 0.0 2.4 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) CDC48_N PF02359.13 EGC32661.1 - 1.3e-23 82.7 0.7 5.5e-23 80.7 0.2 2.4 3 0 0 3 3 1 1 Cell division protein 48 (CDC48), N-terminal domain RuvB_N PF05496.7 EGC32661.1 - 1.9e-14 53.3 0.0 4e-06 26.0 0.0 2.8 3 0 0 3 3 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGC32661.1 - 7.1e-14 52.0 0.0 7.1e-07 29.2 0.0 2.8 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGC32661.1 - 2.9e-13 50.0 0.2 2.6e-05 24.3 0.1 4.1 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC32661.1 - 9.1e-13 48.5 0.1 8.2e-05 22.6 0.0 3.5 2 2 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EGC32661.1 - 1.7e-12 47.4 0.0 6.4e-06 26.0 0.0 2.9 3 0 0 3 3 2 2 AAA domain AAA_17 PF13207.1 EGC32661.1 - 4.8e-12 46.7 0.0 0.00011 23.0 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGC32661.1 - 9.3e-12 44.8 0.2 1e-05 25.2 0.0 3.7 3 2 0 3 3 2 2 AAA domain (dynein-related subfamily) AAA_14 PF13173.1 EGC32661.1 - 3e-11 43.3 0.0 1.9e-05 24.5 0.0 2.5 2 0 0 2 2 2 2 AAA domain CDC48_2 PF02933.12 EGC32661.1 - 4.3e-10 39.0 0.0 1.1e-09 37.8 0.0 1.7 1 0 0 1 1 1 1 Cell division protein 48 (CDC48), domain 2 Zeta_toxin PF06414.7 EGC32661.1 - 9.7e-10 37.8 0.0 0.00071 18.7 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EGC32661.1 - 2.7e-08 32.9 0.0 0.0017 17.1 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus IstB_IS21 PF01695.12 EGC32661.1 - 6e-08 32.3 0.0 0.01 15.2 0.0 2.6 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_25 PF13481.1 EGC32661.1 - 6.1e-08 32.2 2.1 0.31 10.4 0.0 4.2 2 2 1 4 4 4 3 AAA domain Arch_ATPase PF01637.13 EGC32661.1 - 7.2e-08 32.4 0.7 0.048 13.3 0.0 3.9 3 2 2 5 5 4 2 Archaeal ATPase Mg_chelatase PF01078.16 EGC32661.1 - 8.6e-08 31.5 0.4 0.0089 15.2 0.0 2.6 3 0 0 3 3 2 2 Magnesium chelatase, subunit ChlI RNA_helicase PF00910.17 EGC32661.1 - 9.6e-08 32.1 0.0 0.0062 16.6 0.0 2.5 2 0 0 2 2 2 2 RNA helicase AAA_18 PF13238.1 EGC32661.1 - 2e-07 31.3 0.0 0.018 15.3 0.0 2.6 2 0 0 2 2 2 2 AAA domain Vps4_C PF09336.5 EGC32661.1 - 4.6e-07 29.6 0.7 5.9e-06 26.0 0.1 2.5 2 0 0 2 2 2 1 Vps4 C terminal oligomerisation domain NACHT PF05729.7 EGC32661.1 - 6.1e-07 29.2 0.1 0.14 11.8 0.0 3.9 3 1 1 4 4 4 2 NACHT domain AAA_28 PF13521.1 EGC32661.1 - 6.3e-07 29.4 0.0 0.045 13.7 0.0 3.1 3 1 1 4 4 2 2 AAA domain Viral_helicase1 PF01443.13 EGC32661.1 - 9.5e-07 28.5 0.0 0.0016 18.0 0.0 2.4 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase ABC_tran PF00005.22 EGC32661.1 - 1e-06 29.0 0.2 0.011 16.0 0.0 3.2 3 1 0 3 3 2 2 ABC transporter Sigma54_activ_2 PF14532.1 EGC32661.1 - 2.2e-06 27.7 0.0 0.043 13.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain Parvo_NS1 PF01057.12 EGC32661.1 - 4.5e-06 25.7 0.1 0.025 13.4 0.0 2.2 2 0 0 2 2 2 2 Parvovirus non-structural protein NS1 Bac_DnaA PF00308.13 EGC32661.1 - 5.3e-06 26.2 0.0 0.04 13.5 0.0 2.6 2 0 0 2 2 2 2 Bacterial dnaA protein AAA_19 PF13245.1 EGC32661.1 - 7.2e-06 25.6 0.9 0.093 12.4 0.0 2.6 2 0 0 2 2 2 2 Part of AAA domain NB-ARC PF00931.17 EGC32661.1 - 1.5e-05 24.0 0.0 0.099 11.4 0.0 2.3 2 0 0 2 2 2 2 NB-ARC domain KaiC PF06745.8 EGC32661.1 - 2.1e-05 23.7 0.4 2.5 7.1 0.0 3.3 2 1 1 3 3 3 2 KaiC ResIII PF04851.10 EGC32661.1 - 2.8e-05 24.0 0.0 0.0079 16.0 0.0 2.5 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_24 PF13479.1 EGC32661.1 - 4.7e-05 23.0 0.0 0.31 10.5 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EGC32661.1 - 5.3e-05 22.7 0.0 0.42 10.0 0.0 3.2 2 2 0 2 2 2 2 Sigma-54 interaction domain DUF815 PF05673.8 EGC32661.1 - 0.0002 20.3 0.0 0.15 10.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) AAA_3 PF07726.6 EGC32661.1 - 0.00031 20.3 0.0 0.99 9.0 0.0 2.5 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Cytidylate_kin2 PF13189.1 EGC32661.1 - 0.00035 20.5 0.0 0.069 13.0 0.0 2.5 2 0 0 2 2 2 1 Cytidylate kinase-like family NTPase_1 PF03266.10 EGC32661.1 - 0.00095 18.9 0.1 1.4 8.5 0.0 3.5 3 0 0 3 3 3 1 NTPase SKI PF01202.17 EGC32661.1 - 0.001 18.9 0.0 1.8 8.3 0.0 2.8 2 0 0 2 2 2 1 Shikimate kinase ATP-synt_ab PF00006.20 EGC32661.1 - 0.0011 18.5 0.0 1.7 8.0 0.0 2.6 2 0 0 2 2 2 2 ATP synthase alpha/beta family, nucleotide-binding domain AAA_23 PF13476.1 EGC32661.1 - 0.0014 19.0 0.0 1.9 8.7 0.0 2.6 2 0 0 2 2 2 1 AAA domain PhoH PF02562.11 EGC32661.1 - 0.0017 17.6 0.1 0.88 8.7 0.0 2.6 2 0 0 2 2 2 1 PhoH-like protein Rad17 PF03215.10 EGC32661.1 - 0.0024 16.6 0.0 1.4 7.4 0.0 2.3 2 0 0 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_10 PF12846.2 EGC32661.1 - 0.003 17.0 0.6 2.4 7.4 0.0 3.7 4 0 0 4 4 4 1 AAA-like domain UPF0079 PF02367.12 EGC32661.1 - 0.0073 15.9 0.0 4 7.1 0.0 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGC32661.1 - 0.018 14.5 0.0 3.7 7.0 0.0 2.6 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation DUF2075 PF09848.4 EGC32661.1 - 0.022 13.7 0.0 4 6.3 0.0 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) tRNA_lig_kinase PF08303.6 EGC32661.1 - 0.059 13.2 0.0 0.39 10.5 0.0 2.2 2 0 0 2 2 2 0 tRNA ligase kinase domain KAP_NTPase PF07693.9 EGC32661.1 - 0.061 12.3 0.1 4.6 6.1 0.0 3.1 2 2 1 3 3 3 0 KAP family P-loop domain AFG1_ATPase PF03969.11 EGC32661.1 - 0.068 11.9 0.0 6.2 5.5 0.0 2.3 2 0 0 2 2 2 0 AFG1-like ATPase AAA_30 PF13604.1 EGC32661.1 - 0.14 11.7 0.0 11 5.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain DAP3 PF10236.4 EGC32661.1 - 0.17 10.7 0.0 16 4.2 0.0 2.3 2 0 0 2 2 2 0 Mitochondrial ribosomal death-associated protein 3 Hid1 PF12722.2 EGC32662.1 - 3.9e-127 425.2 29.8 6e-127 424.6 20.7 1.3 1 0 0 1 1 1 1 High-temperature-induced dauer-formation protein Dymeclin PF09742.4 EGC32662.1 - 3.2e-90 303.1 0.0 1.1e-89 301.3 0.0 1.9 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Methyltransf_16 PF10294.4 EGC32664.1 - 7.8e-28 97.0 0.1 3.9e-26 91.5 0.0 2.3 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGC32664.1 - 0.0048 17.4 0.2 0.021 15.4 0.0 2.1 2 1 0 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGC32664.1 - 0.028 13.8 0.0 0.052 12.9 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase small domain Daxx PF03344.10 EGC32664.1 - 0.31 9.4 19.8 0.37 9.2 13.7 1.1 1 0 0 1 1 1 0 Daxx Family Ycf1 PF05758.7 EGC32664.1 - 0.91 7.1 13.1 1.1 6.8 9.1 1.2 1 0 0 1 1 1 0 Ycf1 DUF1510 PF07423.6 EGC32664.1 - 2.3 7.5 23.0 4.7 6.5 15.9 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EGC32664.1 - 2.8 5.7 27.6 3.9 5.2 19.1 1.2 1 0 0 1 1 1 0 Nop14-like family APG6 PF04111.7 EGC32664.1 - 9.9 5.1 21.0 16 4.4 14.5 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 ketoacyl-synt PF00109.21 EGC32665.1 - 1.3e-77 260.7 0.0 2.1e-77 260.0 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32665.1 - 2.4e-50 171.6 0.0 4.8e-50 170.6 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Chal_sti_synt_N PF00195.14 EGC32665.1 - 1.6e-45 155.1 0.0 3e-45 154.2 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC32665.1 - 5e-38 129.5 0.0 1.2e-37 128.3 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGC32665.1 - 1.1e-31 110.0 0.0 1.7e-31 109.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase KR PF08659.5 EGC32665.1 - 1.1e-30 106.6 0.0 2.4e-30 105.5 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC32665.1 - 1.1e-22 80.7 0.0 2.9e-22 79.3 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase Chal_sti_synt_C PF02797.10 EGC32665.1 - 2.9e-21 75.9 0.0 1.7e-20 73.4 0.0 2.5 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Methyltransf_12 PF08242.7 EGC32665.1 - 3.5e-16 59.4 0.0 1.3e-15 57.6 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FAE1_CUT1_RppA PF08392.7 EGC32665.1 - 8.1e-12 44.8 1.3 1.1e-11 44.3 0.0 1.8 2 0 0 2 2 2 1 FAE1/Type III polyketide synthase-like protein Methyltransf_23 PF13489.1 EGC32665.1 - 1.5e-10 40.9 0.0 4.1e-10 39.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain ACP_syn_III_C PF08541.5 EGC32665.1 - 5e-09 36.0 0.0 2.5e-08 33.8 0.0 2.2 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal ADH_N PF08240.7 EGC32665.1 - 2.1e-07 30.6 0.0 4.7e-07 29.5 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ACP_syn_III PF08545.5 EGC32665.1 - 1.4e-06 27.9 3.2 1.9e-06 27.4 0.1 2.5 2 1 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Methyltransf_31 PF13847.1 EGC32665.1 - 3.4e-06 26.7 0.1 3.4e-06 26.7 0.0 3.7 4 1 1 5 5 4 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32665.1 - 1.6e-05 24.0 0.1 3.9e-05 22.7 0.1 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGC32665.1 - 1.7e-05 24.9 0.1 8.9e-05 22.6 0.1 2.4 1 1 1 2 2 2 1 Phosphopantetheine attachment site ADH_zinc_N PF00107.21 EGC32665.1 - 2.3e-05 23.9 0.0 5.2e-05 22.8 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC32665.1 - 6.5e-05 23.8 0.0 0.00015 22.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGC32665.1 - 0.00021 21.8 0.0 0.00074 20.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC32665.1 - 0.00023 21.5 0.0 0.00094 19.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Semialdhyde_dh PF01118.19 EGC32665.1 - 0.15 12.3 0.0 0.49 10.6 0.0 1.9 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain APH PF01636.18 EGC32666.1 - 3.9e-09 36.5 0.0 2.7e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC32666.1 - 0.093 12.0 0.0 0.18 11.1 0.0 1.5 1 0 0 1 1 1 0 RIO1 family Pkinase PF00069.20 EGC32667.1 - 7.8e-61 205.4 1.9 3e-58 196.9 1.3 3.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32667.1 - 2e-48 164.7 1.6 3.2e-48 164.0 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGC32667.1 - 6.5e-09 36.0 0.1 7e-08 32.7 0.1 3.1 1 0 0 1 1 1 1 P21-Rho-binding domain SBF2 PF12335.3 EGC32667.1 - 1.6e-08 34.1 0.4 1.6e-08 34.1 0.3 2.3 2 0 0 2 2 2 1 Myotubularin protein C1_1 PF00130.17 EGC32667.1 - 2.5e-08 33.5 5.4 4.4e-08 32.7 3.7 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) CH PF00307.26 EGC32667.1 - 9.2e-07 28.8 0.2 9.4e-06 25.6 0.1 2.9 1 0 0 1 1 1 1 Calponin homology (CH) domain RCC1 PF00415.13 EGC32668.1 - 6.3e-65 215.2 2.5 6.7e-10 39.0 0.0 8.7 7 3 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC32668.1 - 3.6e-40 134.7 37.0 9.4e-10 37.8 0.3 8.8 9 0 0 9 9 9 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGC32668.1 - 8.1e-13 48.3 6.4 2.3e-11 43.6 1.8 2.8 2 0 0 2 2 2 2 BTB/POZ domain Ribosomal_L27 PF01016.14 EGC32668.1 - 0.048 13.4 0.3 1.8 8.4 0.0 3.0 3 0 0 3 3 3 0 Ribosomal L27 protein BACK PF07707.10 EGC32668.1 - 0.088 12.6 4.9 0.3 10.9 0.2 2.6 2 0 0 2 2 2 0 BTB And C-terminal Kelch EGF_2 PF07974.8 EGC32669.1 - 5.4e-38 128.8 310.4 2.1e-05 24.5 9.5 16.1 15 1 0 15 15 15 13 EGF-like domain SKG6 PF08693.5 EGC32669.1 - 0.16 11.2 4.5 0.25 10.6 2.4 1.8 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Laminin_EGF PF00053.19 EGC32669.1 - 3 7.8 243.7 0.046 13.6 7.3 15.3 9 3 6 15 15 15 0 Laminin EGF-like (Domains III and V) KxDL PF10241.4 EGC32670.1 - 0.0057 16.5 2.8 0.0057 16.5 2.0 2.8 2 1 0 2 2 2 1 Uncharacterized conserved protein Neur_chan_memb PF02932.11 EGC32670.1 - 0.02 14.7 2.0 0.03 14.2 1.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region O-ag_pol_Wzy PF14296.1 EGC32670.1 - 0.022 13.3 0.8 0.026 13.0 0.6 1.2 1 0 0 1 1 1 0 O-antigen polysaccharide polymerase Wzy DUF318 PF03773.8 EGC32670.1 - 0.15 11.0 0.1 0.19 10.6 0.1 1.2 1 0 0 1 1 1 0 Predicted permease Pex24p PF06398.6 EGC32670.1 - 2.9 6.5 8.7 6.7 5.4 6.0 1.7 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin DUF763 PF05559.6 EGC32670.1 - 6.1 5.6 6.9 9.6 5.0 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF763) DUF106 PF01956.11 EGC32670.1 - 6.6 6.2 11.1 74 2.8 7.7 2.2 1 1 0 1 1 1 0 Integral membrane protein DUF106 Bromodomain PF00439.20 EGC32671.1 - 3e-22 78.3 2.2 3.4e-22 78.1 1.5 1.0 1 0 0 1 1 1 1 Bromodomain UCH_1 PF13423.1 EGC32672.1 - 4e-50 170.9 10.6 8.9e-50 169.7 7.4 1.6 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase RNase_T PF00929.19 EGC32672.1 - 7.5e-26 91.3 1.3 1.7e-25 90.2 0.0 2.4 4 0 0 4 4 4 1 Exonuclease UCH PF00443.24 EGC32672.1 - 2.5e-10 39.9 12.5 1.1e-09 37.8 8.7 2.1 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase Curto_V2 PF07325.6 EGC32672.1 - 0.021 14.5 0.0 0.058 13.0 0.0 1.7 1 0 0 1 1 1 0 Curtovirus V2 protein WD40 PF00400.27 EGC32672.1 - 0.03 14.2 0.0 8.7 6.4 0.0 2.8 2 0 0 2 2 2 0 WD domain, G-beta repeat Tmemb_185A PF10269.4 EGC32673.1 - 0.018 14.6 2.8 0.018 14.6 1.9 3.4 1 1 2 4 4 4 0 Transmembrane Fragile-X-F protein PAP2_3 PF14378.1 EGC32673.1 - 3.7 7.0 8.1 0.084 12.3 0.8 1.7 2 0 0 2 2 2 0 PAP2 superfamily FERM_M PF00373.13 EGC32674.1 - 1e-21 77.4 0.5 2.2e-21 76.3 0.4 1.5 1 0 0 1 1 1 1 FERM central domain FERM_N PF09379.5 EGC32674.1 - 0.0035 17.3 0.0 0.008 16.2 0.0 1.6 1 0 0 1 1 1 1 FERM N-terminal domain DUF2711 PF10924.3 EGC32674.1 - 0.011 15.2 0.1 0.022 14.2 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2711) zf-RING_2 PF13639.1 EGC32676.1 - 2.6e-11 43.1 9.4 4.4e-11 42.4 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC32676.1 - 9.5e-09 34.8 7.3 1.4e-08 34.2 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC32676.1 - 3e-08 33.6 5.2 6.3e-08 32.6 3.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC32676.1 - 2.8e-07 30.0 11.5 4.9e-07 29.2 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32676.1 - 1.1e-06 28.5 10.2 1.8e-06 27.8 7.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32676.1 - 1.1e-05 25.0 9.4 1.8e-05 24.3 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain IBR PF01485.16 EGC32676.1 - 0.00096 18.9 7.5 0.0027 17.5 5.2 1.8 1 0 0 1 1 1 1 IBR domain zf-RING_4 PF14570.1 EGC32676.1 - 0.0011 18.4 10.6 0.0021 17.6 7.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC32676.1 - 0.0089 15.7 2.3 0.044 13.4 1.6 2.3 1 1 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC32676.1 - 0.0092 15.8 11.0 0.026 14.4 6.6 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC32676.1 - 0.018 14.5 4.8 0.038 13.5 3.3 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC32676.1 - 0.022 14.6 4.3 0.046 13.5 3.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC32676.1 - 0.034 14.0 7.2 0.063 13.1 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MIZ PF02891.15 EGC32676.1 - 0.13 11.7 7.6 0.26 10.8 5.2 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-P11 PF03854.9 EGC32676.1 - 2.8 7.4 7.0 7.8 6.0 4.9 1.7 1 1 0 1 1 1 0 P-11 zinc finger DUF763 PF05559.6 EGC32676.1 - 6 5.7 9.4 0.59 9.0 2.3 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF763) Peptidase_M1 PF01433.15 EGC32677.1 - 2.6e-126 421.8 6.1 4.8e-126 420.9 4.3 1.5 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGC32677.1 - 1.1e-39 136.6 0.0 2e-39 135.7 0.0 1.4 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGC32677.1 - 1.4e-17 63.8 0.1 2.5e-17 63.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily 4HBT PF03061.17 EGC32678.1 - 1.3e-12 47.6 0.0 2.2e-12 46.9 0.0 1.4 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGC32678.1 - 0.0095 15.9 0.0 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) CAP_C PF08603.6 EGC32679.1 - 7e-08 31.9 4.7 1.2e-07 31.2 3.2 1.4 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal SEC-C PF02810.10 EGC32679.1 - 1.4e-07 30.8 8.6 1.4e-07 30.8 6.0 1.8 2 0 0 2 2 2 1 SEC-C motif TBCC PF07986.7 EGC32679.1 - 0.00076 18.8 3.9 0.002 17.4 2.0 2.0 1 1 1 2 2 2 1 Tubulin binding cofactor C Big_1 PF02369.11 EGC32679.1 - 0.0048 16.7 0.7 0.013 15.3 0.5 1.8 1 0 0 1 1 1 1 Bacterial Ig-like domain (group 1) HEAT_2 PF13646.1 EGC32680.1 - 8.5e-05 22.7 0.0 0.05 13.8 0.0 3.8 2 1 1 3 3 3 2 HEAT repeats HEAT PF02985.17 EGC32680.1 - 0.00095 19.0 0.3 7.6 6.9 0.0 4.3 4 0 0 4 4 4 2 HEAT repeat Cohesin_HEAT PF12765.2 EGC32680.1 - 0.029 14.3 3.1 1.7 8.7 0.3 3.7 3 0 0 3 3 3 0 HEAT repeat associated with sister chromatid cohesion DUF2366 PF10171.4 EGC32681.1 - 0.01 15.3 0.2 0.18 11.2 0.0 2.4 2 1 1 3 3 3 0 Uncharacterised conserved protein (DUF2366) Na_H_Exchanger PF00999.16 EGC32682.1 - 2.6e-56 190.8 54.1 3.6e-56 190.3 37.5 1.2 1 0 0 1 1 1 1 Sodium/hydrogen exchanger family N_NLPC_P60 PF12912.2 EGC32682.1 - 0.069 13.2 0.0 0.17 11.9 0.0 1.7 1 0 0 1 1 1 0 NLPC_P60 stabilising domain, N term TMEM154 PF15102.1 EGC32682.1 - 4.2 7.0 7.0 2.6 7.7 0.1 2.9 3 0 0 3 3 3 0 TMEM154 protein family ABC_tran PF00005.22 EGC32683.1 - 1.9e-54 183.6 2.8 2.7e-26 92.5 0.0 3.0 3 0 0 3 3 2 2 ABC transporter AAA_21 PF13304.1 EGC32683.1 - 3.5e-22 79.7 23.5 7.9e-13 49.0 2.1 5.3 3 2 1 4 4 4 3 AAA domain ABC_tran_2 PF12848.2 EGC32683.1 - 4.1e-10 39.3 1.8 4.1e-10 39.3 1.3 3.5 4 0 0 4 4 3 1 ABC transporter SbcCD_C PF13558.1 EGC32683.1 - 1.3e-06 28.1 1.0 0.042 13.7 0.0 3.7 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_25 PF13481.1 EGC32683.1 - 4.5e-06 26.1 0.1 0.54 9.6 0.0 4.1 4 0 0 4 4 4 1 AAA domain AAA_29 PF13555.1 EGC32683.1 - 5.3e-06 25.8 2.8 0.029 13.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain MobB PF03205.9 EGC32683.1 - 1.1e-05 25.1 0.6 0.028 14.1 0.1 2.8 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGC32683.1 - 1.2e-05 25.2 0.0 0.089 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGC32683.1 - 2.2e-05 25.2 8.4 0.43 11.4 0.0 3.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGC32683.1 - 2.9e-05 23.3 0.2 0.0051 16.0 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC32683.1 - 3.3e-05 24.3 0.3 0.36 11.3 0.0 2.9 2 0 0 2 2 2 2 Miro-like protein AAA PF00004.24 EGC32683.1 - 3.8e-05 23.8 0.1 0.091 12.9 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC32683.1 - 3.8e-05 23.7 0.2 0.27 11.2 0.1 2.5 2 0 0 2 2 2 2 AAA ATPase domain SMC_N PF02463.14 EGC32683.1 - 0.00014 21.1 1.6 0.00014 21.1 1.1 4.0 3 2 0 4 4 3 2 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGC32683.1 - 0.00025 21.4 0.0 0.00025 21.4 0.0 5.2 3 1 0 3 3 2 1 AAA domain MMR_HSR1 PF01926.18 EGC32683.1 - 0.00026 20.9 0.0 0.098 12.6 0.0 3.0 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_28 PF13521.1 EGC32683.1 - 0.00029 20.8 1.9 0.49 10.3 0.0 3.1 2 1 0 2 2 2 2 AAA domain AAA_22 PF13401.1 EGC32683.1 - 0.00059 19.9 3.0 0.49 10.5 0.1 3.6 2 2 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGC32683.1 - 0.0014 18.7 0.0 3.2 7.9 0.0 2.9 2 0 0 2 2 2 2 RNA helicase NACHT PF05729.7 EGC32683.1 - 0.005 16.5 2.3 1.8 8.2 0.1 3.0 3 0 0 3 3 3 1 NACHT domain Dynamin_N PF00350.18 EGC32683.1 - 0.015 15.1 0.6 0.015 15.1 0.5 3.7 4 1 0 4 4 3 0 Dynamin family AAA_18 PF13238.1 EGC32683.1 - 0.026 14.8 0.8 0.026 14.8 0.5 4.6 4 1 0 4 4 4 0 AAA domain UPF0079 PF02367.12 EGC32683.1 - 0.03 13.9 0.7 3 7.5 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 ArgK PF03308.11 EGC32683.1 - 0.035 12.8 4.1 0.32 9.7 0.0 2.7 3 0 0 3 3 3 0 ArgK protein T2SE PF00437.15 EGC32683.1 - 0.04 12.8 0.1 8.5 5.1 0.0 2.5 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGC32683.1 - 0.047 13.2 0.2 4.1 6.9 0.0 2.4 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGC32683.1 - 0.052 13.4 7.4 2.7 7.8 0.0 4.2 4 1 0 4 4 4 0 AAA domain PRK PF00485.13 EGC32683.1 - 0.052 13.1 1.5 13 5.3 0.0 3.6 4 0 0 4 4 3 0 Phosphoribulokinase / Uridine kinase family AAA_19 PF13245.1 EGC32683.1 - 0.11 12.2 0.2 15 5.4 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain MutS_V PF00488.16 EGC32683.1 - 0.18 11.2 0.5 9.1 5.6 0.0 2.3 2 0 0 2 2 2 0 MutS domain V AAA_10 PF12846.2 EGC32683.1 - 0.27 10.6 11.1 0.28 10.5 0.3 3.2 2 1 1 3 3 3 0 AAA-like domain ABC_ATPase PF09818.4 EGC32683.1 - 0.29 9.6 2.1 11 4.4 0.0 2.9 4 0 0 4 4 4 0 Predicted ATPase of the ABC class NB-ARC PF00931.17 EGC32683.1 - 0.52 9.1 8.2 0.84 8.4 0.0 3.0 3 1 0 3 3 3 0 NB-ARC domain KAP_NTPase PF07693.9 EGC32683.1 - 1.3 7.8 0.0 1.3 7.8 0.0 3.8 4 1 1 5 5 5 0 KAP family P-loop domain Ribosomal_L3 PF00297.17 EGC32684.1 - 7.4e-122 405.7 10.0 9e-122 405.5 6.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L3 tRNA_bind PF01588.15 EGC32685.1 - 4.5e-30 103.3 0.1 9.3e-30 102.3 0.1 1.6 1 0 0 1 1 1 1 Putative tRNA binding domain GST_C_3 PF14497.1 EGC32685.1 - 0.0024 18.3 0.1 0.0043 17.5 0.1 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Viral_protease PF08715.5 EGC32685.1 - 0.076 12.0 0.0 0.12 11.4 0.0 1.3 1 0 0 1 1 1 0 Papain like viral protease DUF2838 PF10998.3 EGC32687.1 - 7.8e-35 119.1 10.6 7.8e-35 119.1 7.4 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) WD40 PF00400.27 EGC32688.1 - 7e-18 63.7 9.3 6.4e-06 25.8 0.8 5.8 7 0 0 7 7 7 3 WD domain, G-beta repeat SpoU_methylase PF00588.14 EGC32689.1 - 5.7e-30 104.0 0.1 1.6e-29 102.5 0.1 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family SpoU_sub_bind PF08032.7 EGC32689.1 - 2.4e-05 24.3 1.1 7.1e-05 22.8 0.1 2.4 2 0 0 2 2 2 1 RNA 2'-O ribose methyltransferase substrate binding Methyltrn_RNA_4 PF09936.4 EGC32689.1 - 0.00011 21.7 0.0 0.00044 19.8 0.0 2.0 1 1 0 1 1 1 1 SAM-dependent RNA methyltransferase Neur_chan_memb PF02932.11 EGC32689.1 - 5.4 6.8 11.3 8.8 6.1 7.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region PIP5K PF01504.13 EGC32690.1 - 8.5e-74 247.8 0.1 1.1e-73 247.4 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF4441 PF14536.1 EGC32690.1 - 0.05 13.5 0.7 1.2 9.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) Pkinase PF00069.20 EGC32691.1 - 2.6e-47 161.1 2.3 5.7e-46 156.7 0.0 3.5 2 1 0 2 2 2 1 Protein kinase domain Kdo PF06293.9 EGC32691.1 - 0.0086 15.1 0.1 0.017 14.2 0.1 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC32691.1 - 0.012 15.3 0.0 0.11 12.2 0.0 2.0 1 1 1 2 2 2 0 Phosphotransferase enzyme family Alpha_kinase PF02816.13 EGC32692.1 - 2.1e-57 193.8 0.2 2.1e-57 193.8 0.2 2.1 2 0 0 2 2 2 1 Alpha-kinase family ArfGap PF01412.13 EGC32692.1 - 2.1e-20 72.6 0.0 2.1e-20 72.6 0.0 3.2 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SHOCT PF09851.4 EGC32692.1 - 0.0035 16.7 0.1 0.0059 16.0 0.0 1.3 1 0 0 1 1 1 1 Short C-terminal domain AA_permease_2 PF13520.1 EGC32694.1 - 5.8e-50 170.0 25.3 6.7e-50 169.8 17.5 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC32694.1 - 6.8e-46 156.5 23.2 7.7e-46 156.4 16.1 1.0 1 0 0 1 1 1 1 Amino acid permease Spore_permease PF03845.8 EGC32694.1 - 0.0022 16.6 17.9 0.024 13.2 2.2 2.1 2 0 0 2 2 2 2 Spore germination protein DUF843 PF05814.6 EGC32694.1 - 0.53 10.1 3.7 1.4 8.7 2.6 1.6 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) Pkinase PF00069.20 EGC32696.1 - 1.2e-80 270.4 0.0 1.4e-80 270.1 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32696.1 - 8.6e-41 139.7 0.0 1.2e-40 139.2 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC32696.1 - 1.8e-06 27.1 0.3 4.9e-06 25.7 0.2 1.7 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC32696.1 - 7.3e-05 22.1 2.7 0.00067 19.0 1.4 2.4 2 1 0 2 2 2 1 PhoP regulatory network protein YrbL Kinase-like PF14531.1 EGC32696.1 - 0.0001 21.3 0.0 0.011 14.6 0.0 2.3 1 1 1 2 2 2 2 Kinase-like APH PF01636.18 EGC32696.1 - 0.021 14.5 0.0 0.088 12.5 0.0 1.8 1 1 1 2 2 2 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC32696.1 - 0.054 13.0 1.0 0.31 10.5 0.7 2.1 1 1 0 1 1 1 0 Choline/ethanolamine kinase SHS2_FTSA PF02491.15 EGC32696.1 - 0.23 11.3 1.7 0.49 10.3 1.2 1.5 1 0 0 1 1 1 0 SHS2 domain inserted in FTSA PH PF00169.24 EGC32697.1 - 7.1e-09 35.8 0.2 7.1e-09 35.8 0.1 2.8 2 1 0 2 2 2 1 PH domain SAM_1 PF00536.25 EGC32697.1 - 3.5e-08 33.5 0.0 7e-08 32.5 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC32697.1 - 6.2e-08 32.3 0.0 2.2e-07 30.5 0.0 2.0 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) PH_8 PF15409.1 EGC32697.1 - 4.9e-05 23.3 0.2 0.00015 21.7 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF4139 PF13598.1 EGC32697.1 - 9.3e-05 21.8 0.1 0.02 14.2 0.0 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4139) PH_11 PF15413.1 EGC32697.1 - 0.0068 16.6 2.1 0.076 13.2 1.4 2.7 1 1 0 1 1 1 1 Pleckstrin homology domain NRDE PF05742.7 EGC32698.1 - 9.2e-33 113.7 0.5 9.7e-21 74.2 0.1 3.1 1 1 1 2 2 2 2 NRDE protein EGF_2 PF07974.8 EGC32699.1 - 0.0051 16.9 15.8 0.0051 16.9 10.9 3.3 4 0 0 4 4 4 1 EGF-like domain Laminin_EGF PF00053.19 EGC32699.1 - 0.022 14.6 23.2 0.054 13.4 6.8 2.7 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) PBD PF00786.23 EGC32700.1 - 6.3e-17 61.7 0.3 6.3e-17 61.7 0.2 2.5 3 0 0 3 3 3 1 P21-Rho-binding domain WH2 PF02205.15 EGC32700.1 - 0.00017 21.0 0.0 0.00038 19.9 0.0 1.6 1 0 0 1 1 1 1 WH2 motif ketoacyl-synt PF00109.21 EGC32701.1 - 3e-61 207.1 0.0 4.5e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32701.1 - 1.5e-45 155.9 0.0 2.4e-45 155.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC32701.1 - 2.3e-41 141.3 0.0 6.2e-41 139.9 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC32701.1 - 7e-32 109.7 0.0 5.4e-31 106.9 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC32701.1 - 2.8e-23 82.4 0.0 2.2e-22 79.6 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGC32701.1 - 8.4e-19 68.0 0.0 7.1e-16 58.5 0.0 2.8 3 0 0 3 3 2 2 short chain dehydrogenase Methyltransf_12 PF08242.7 EGC32701.1 - 1.3e-18 67.3 0.0 1.3e-18 67.3 0.0 4.8 5 0 0 5 5 4 1 Methyltransferase domain PS-DH PF14765.1 EGC32701.1 - 2.1e-18 66.5 0.0 3.3e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGC32701.1 - 4.3e-11 42.6 0.4 1.4e-07 31.1 0.0 2.7 2 1 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC32701.1 - 7.2e-08 33.3 0.0 1.7e-07 32.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC32701.1 - 1e-06 28.4 0.0 2.4e-06 27.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EGC32701.1 - 1.7e-06 28.2 0.0 3.3e-05 24.0 0.1 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EGC32701.1 - 0.0002 21.7 0.0 0.00072 19.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32701.1 - 0.00026 20.7 0.0 0.00085 19.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32701.1 - 0.00059 20.3 0.0 0.0028 18.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32701.1 - 0.0012 17.8 0.0 0.0026 16.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain RmlD_sub_bind PF04321.12 EGC32701.1 - 0.03 13.2 0.1 0.76 8.6 0.0 2.7 2 1 0 2 2 2 0 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGC32701.1 - 1.2 9.1 0.0 25 4.7 0.0 3.1 4 0 0 4 4 4 0 NADH(P)-binding Beach PF02138.13 EGC32702.1 - 2.6e-111 371.3 0.5 2.6e-111 371.3 0.4 2.5 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EGC32702.1 - 1.4e-21 76.2 0.4 8.9e-21 73.7 0.0 2.7 2 0 0 2 2 2 1 PH domain associated with Beige/BEACH WD40 PF00400.27 EGC32702.1 - 1.4e-11 43.8 5.0 7.6e-06 25.6 0.2 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat EGF_2 PF07974.8 EGC32703.1 - 1.1 9.5 5.1 0.69 10.1 0.8 2.2 2 0 0 2 2 2 0 EGF-like domain tRNA-synt_2b PF00587.20 EGC32704.1 - 5.3e-38 130.3 0.1 8.1e-38 129.6 0.1 1.3 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) Seryl_tRNA_N PF02403.17 EGC32704.1 - 1.2e-17 63.8 4.3 1.2e-17 63.8 3.0 2.2 2 0 0 2 2 2 1 Seryl-tRNA synthetase N-terminal domain Tropomyosin_1 PF12718.2 EGC32704.1 - 0.0019 18.0 3.2 0.0043 16.9 2.2 1.5 1 0 0 1 1 1 1 Tropomyosin like IncA PF04156.9 EGC32704.1 - 0.17 11.4 3.1 0.12 11.9 0.5 1.9 2 0 0 2 2 2 0 IncA protein UPF0449 PF15136.1 EGC32704.1 - 9 6.5 10.0 0.41 10.8 1.7 2.6 4 0 0 4 4 4 0 Uncharacterised protein family UPF0449 Metallophos PF00149.23 EGC32705.1 - 4.1e-16 58.9 0.9 5.6e-16 58.5 0.2 1.5 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGC32705.1 - 2.7e-12 46.5 0.2 7.1e-12 45.2 0.1 1.8 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 EGC32705.1 - 2.1e-05 24.4 0.0 4.8e-05 23.2 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 EGC32705.1 - 0.0013 17.3 0.0 0.1 11.1 0.0 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase GNVR PF13807.1 EGC32705.1 - 0.11 12.2 0.0 0.28 10.9 0.0 1.6 1 0 0 1 1 1 0 G-rich domain on putative tyrosine kinase VMA21 PF09446.5 EGC32705.1 - 0.26 11.2 3.3 0.61 10.0 2.3 1.6 1 0 0 1 1 1 0 VMA21-like domain ICL PF00463.16 EGC32706.1 - 1.1e-147 492.4 0.7 3.6e-79 266.3 0.0 2.1 1 1 1 2 2 2 2 Isocitrate lyase family PEP_mutase PF13714.1 EGC32706.1 - 1.2e-17 63.9 0.0 2.2e-17 63.0 0.0 1.4 1 1 0 1 1 1 1 Phosphoenolpyruvate phosphomutase CBFD_NFYB_HMF PF00808.18 EGC32707.1 - 1.5e-21 76.1 1.3 1.7e-21 76.0 0.1 1.7 2 0 0 2 2 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC32707.1 - 3.8e-08 33.3 0.0 5.9e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-T PF15511.1 EGC32707.1 - 0.00072 18.9 8.9 0.00094 18.5 6.2 1.2 1 0 0 1 1 1 1 Centromere kinetochore component CENP-T Daxx PF03344.10 EGC32707.1 - 0.0041 15.7 19.6 0.0038 15.7 13.6 1.1 1 0 0 1 1 1 1 Daxx Family CDC45 PF02724.9 EGC32707.1 - 0.05 11.6 17.9 0.05 11.6 12.4 1.1 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGC32707.1 - 0.086 12.1 23.6 0.095 11.9 16.4 1.1 1 0 0 1 1 1 0 SDA1 RRN3 PF05327.6 EGC32707.1 - 0.25 9.4 13.1 0.24 9.4 9.1 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 DUF3807 PF12720.2 EGC32707.1 - 0.26 11.4 15.1 0.38 10.8 10.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) Merozoite_SPAM PF07133.6 EGC32707.1 - 0.43 10.4 30.8 0.69 9.7 21.4 1.3 1 0 0 1 1 1 0 Merozoite surface protein (SPAM) Peptidase_M26_N PF05342.9 EGC32707.1 - 1.1 8.1 16.2 2 7.2 11.2 1.4 1 1 0 1 1 1 0 M26 IgA1-specific Metallo-endopeptidase N-terminal region Nop14 PF04147.7 EGC32707.1 - 1.1 7.0 29.4 1.4 6.7 20.4 1.1 1 0 0 1 1 1 0 Nop14-like family eIF-3c_N PF05470.7 EGC32707.1 - 1.3 7.0 16.5 1.6 6.7 11.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus CDC27 PF09507.5 EGC32707.1 - 1.6 7.8 26.4 1.9 7.6 18.3 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 DUF2890 PF11081.3 EGC32707.1 - 1.7 8.6 20.8 0.62 10.1 13.0 1.4 2 0 0 2 2 1 0 Protein of unknown function (DUF2890) Ycf1 PF05758.7 EGC32707.1 - 1.9 6.1 14.9 2 6.0 10.3 1.2 1 0 0 1 1 1 0 Ycf1 PLRV_ORF5 PF01690.12 EGC32707.1 - 2.8 7.0 10.6 2.9 6.9 7.3 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Tim54 PF11711.3 EGC32707.1 - 4 5.9 10.0 4.6 5.7 6.9 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TRAP_alpha PF03896.11 EGC32707.1 - 4.3 6.2 16.9 6.2 5.7 11.7 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TP53IP5 PF15331.1 EGC32707.1 - 4.9 6.9 9.4 6.9 6.5 6.5 1.2 1 0 0 1 1 1 0 Cellular tumour antigen p53-inducible 5 DUF966 PF06136.8 EGC32707.1 - 6.7 6.0 11.9 7.4 5.8 8.2 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Vfa1 PF08432.5 EGC32707.1 - 7 6.6 23.6 12 5.9 16.4 1.4 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 APG6 PF04111.7 EGC32707.1 - 9.2 5.2 16.0 12 4.7 11.1 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 V_ATPase_I PF01496.14 EGC32707.1 - 9.4 3.9 7.6 8.6 4.0 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IU_nuc_hydro PF01156.14 EGC32708.1 - 4.5e-93 311.8 0.0 5.1e-93 311.7 0.0 1.0 1 0 0 1 1 1 1 Inosine-uridine preferring nucleoside hydrolase DUF3567 PF12091.3 EGC32710.1 - 0.15 12.0 0.2 19 5.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3567) dsrm PF00035.20 EGC32711.1 - 3.6e-23 81.8 0.6 2.6e-10 40.7 0.1 2.8 2 0 0 2 2 2 2 Double-stranded RNA binding motif OB_NTP_bind PF07717.11 EGC32711.1 - 1e-19 70.4 0.0 1e-19 70.4 0.0 3.0 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGC32711.1 - 2e-19 69.4 0.0 2e-19 69.4 0.0 3.7 3 1 0 3 3 3 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGC32711.1 - 8.3e-12 44.8 0.0 3.2e-11 42.9 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC32711.1 - 1.6e-09 37.5 0.1 4.7e-09 35.9 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Dicer_dimer PF03368.9 EGC32711.1 - 0.00014 21.5 0.0 0.0092 15.7 0.0 2.7 2 0 0 2 2 2 1 Dicer dimerisation domain AAA_22 PF13401.1 EGC32711.1 - 0.00016 21.8 0.1 0.00051 20.1 0.0 1.9 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EGC32711.1 - 0.0068 15.3 0.1 0.048 12.5 0.0 2.1 2 0 0 2 2 2 1 Type II/IV secretion system protein AAA_14 PF13173.1 EGC32711.1 - 0.044 13.6 0.3 0.044 13.6 0.2 4.9 5 1 0 5 5 5 0 AAA domain CDP-OH_P_transf PF01066.16 EGC32712.1 - 2.3e-18 66.3 1.4 2.3e-18 66.3 1.0 2.9 2 2 0 2 2 2 1 CDP-alcohol phosphatidyltransferase DmsC PF04976.7 EGC32712.1 - 0.00034 19.9 10.4 0.00067 19.0 7.2 1.4 1 0 0 1 1 1 1 DMSO reductase anchor subunit (DmsC) p450 PF00067.17 EGC32713.1 - 2.2e-90 303.3 0.2 2.5e-90 303.2 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DRMBL PF07522.9 EGC32714.1 - 5e-24 84.4 0.0 8.7e-24 83.6 0.0 1.4 1 0 0 1 1 1 1 DNA repair metallo-beta-lactamase Lactamase_B_2 PF12706.2 EGC32714.1 - 3.2e-13 49.6 0.3 1.3e-12 47.6 0.2 1.8 1 1 1 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGC32714.1 - 0.00074 19.2 0.4 0.0013 18.4 0.3 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily RMMBL PF07521.7 EGC32714.1 - 0.047 13.5 0.0 0.13 12.0 0.0 1.8 2 0 0 2 2 2 0 RNA-metabolising metallo-beta-lactamase CBM49 PF09478.5 EGC32715.1 - 0.00036 20.5 0.9 0.003 17.6 0.6 2.3 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 2OG-FeII_Oxy_3 PF13640.1 EGC32716.1 - 2.9e-15 56.5 0.0 4.7e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGC32716.1 - 0.00028 21.1 0.0 0.00071 19.8 0.0 1.7 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGC32716.1 - 0.034 13.7 0.0 0.085 12.5 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily RGCC PF15151.1 EGC32716.1 - 0.11 12.8 1.8 1.3 9.4 0.1 2.2 1 1 0 2 2 2 0 Response gene to complement 32 protein family Ras PF00071.17 EGC32717.1 - 2e-30 105.2 0.0 2.5e-30 105.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32717.1 - 1.7e-11 44.6 0.0 3.8e-11 43.5 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC32717.1 - 0.0021 17.3 0.0 0.0031 16.7 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family PduV-EutP PF10662.4 EGC32717.1 - 0.0034 16.8 0.1 0.65 9.4 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGC32717.1 - 0.027 14.6 0.0 0.19 11.8 0.0 2.0 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGC32717.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 NACHT domain AAA PF00004.24 EGC32717.1 - 0.13 12.5 0.0 0.32 11.1 0.0 1.8 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC32717.1 - 0.13 12.2 0.0 0.22 11.4 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Ras PF00071.17 EGC32718.1 - 3.3e-24 85.1 0.0 4.5e-24 84.6 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32718.1 - 1.3e-09 38.5 0.2 2e-08 34.7 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EGC32718.1 - 0.013 15.6 0.3 2.6 8.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain tRNA-synt_1 PF00133.17 EGC32719.1 - 1.9e-201 670.1 1.0 1.9e-201 670.1 0.7 2.7 2 2 0 2 2 2 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC32719.1 - 9.9e-42 142.2 0.1 9.9e-42 142.2 0.1 2.4 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGC32719.1 - 3.1e-14 52.4 10.5 2.1e-07 29.9 0.0 4.9 5 1 0 5 5 5 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGC32719.1 - 1.5e-05 24.3 0.0 1.5e-05 24.3 0.0 3.6 2 1 1 3 3 3 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1e PF01406.14 EGC32719.1 - 0.035 13.2 0.0 0.035 13.2 0.0 2.9 3 0 0 3 3 3 0 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGC32719.1 - 0.43 9.3 0.0 0.43 9.3 0.0 3.1 3 0 0 3 3 3 0 tRNA synthetases class I (R) Bud13 PF09736.4 EGC32719.1 - 8.2 6.6 23.8 7 6.9 14.5 2.2 2 0 0 2 2 2 0 Pre-mRNA-splicing factor of RES complex Sec1 PF00995.18 EGC32721.1 - 6.8e-93 312.2 14.8 8.4e-93 311.9 10.3 1.0 1 0 0 1 1 1 1 Sec1 family RabGAP-TBC PF00566.13 EGC32722.1 - 3.7e-53 180.1 1.0 3.7e-53 180.1 0.7 1.9 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Cullin_binding PF03556.10 EGC32722.1 - 0.055 13.6 0.6 4.2 7.5 0.0 2.6 2 0 0 2 2 2 0 Cullin binding RabGAP-TBC PF00566.13 EGC32723.1 - 1.3e-56 191.4 2.0 1.3e-56 191.4 1.4 2.3 2 0 0 2 2 2 1 Rab-GTPase-TBC domain KNOX2 PF03791.8 EGC32723.1 - 0.0012 18.0 0.1 0.0029 16.8 0.1 1.6 1 0 0 1 1 1 1 KNOX2 domain NRDE-2 PF08424.5 EGC32723.1 - 9.2 5.0 12.4 16 4.2 8.6 1.3 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference YugN PF08868.5 EGC32725.1 - 0.06 12.9 0.2 0.12 12.0 0.2 1.5 1 0 0 1 1 1 0 YugN-like family Ion_trans PF00520.26 EGC32725.1 - 0.22 10.7 1.9 0.36 10.0 1.3 1.3 1 0 0 1 1 1 0 Ion transport protein Pox_A9 PF04835.7 EGC32725.1 - 0.22 11.4 0.7 0.39 10.6 0.5 1.4 1 0 0 1 1 1 0 A9 protein conserved region YugN PF08868.5 EGC32726.1 - 0.01 15.4 0.1 0.014 15.0 0.1 1.3 1 0 0 1 1 1 0 YugN-like family Folate_carrier PF01770.13 EGC32726.1 - 0.043 12.3 0.1 0.049 12.1 0.1 1.0 1 0 0 1 1 1 0 Reduced folate carrier Pox_A9 PF04835.7 EGC32726.1 - 0.06 13.2 0.7 0.086 12.7 0.5 1.3 1 0 0 1 1 1 0 A9 protein conserved region Ion_trans PF00520.26 EGC32726.1 - 0.06 12.5 2.3 0.079 12.2 1.6 1.2 1 0 0 1 1 1 0 Ion transport protein Pkinase PF00069.20 EGC32729.1 - 4.9e-63 212.7 0.0 9.3e-63 211.7 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32729.1 - 5.9e-46 156.6 0.1 9.5e-46 155.9 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC32729.1 - 0.00031 20.5 0.0 0.00049 19.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC32729.1 - 0.00039 20.0 0.1 0.0013 18.3 0.0 1.8 1 1 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGC32729.1 - 0.01 14.9 0.0 0.019 14.0 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC32729.1 - 0.082 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Kinase-like Det1 PF09737.4 EGC32730.1 - 1.1e-111 373.5 13.2 7.9e-82 275.1 2.5 2.2 2 0 0 2 2 2 2 De-etiolated protein 1 Det1 Laminin_EGF PF00053.19 EGC32731.1 - 0.005 16.7 28.0 0.069 13.0 4.7 3.3 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) PMP1_2 PF08114.6 EGC32731.1 - 0.92 9.0 2.5 1.8 8.1 1.8 1.4 1 0 0 1 1 1 0 ATPase proteolipid family Gamma-thionin PF00304.15 EGC32731.1 - 6.2 6.9 16.7 2.7 8.0 2.8 2.7 2 0 0 2 2 2 0 Gamma-thionin family Laminin_EGF PF00053.19 EGC32732.1 - 0.0018 18.1 37.2 0.1 12.5 5.5 3.7 2 1 1 3 3 3 3 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC32732.1 - 0.0069 16.3 3.9 0.0069 16.3 2.7 3.2 3 0 0 3 3 3 1 Human growth factor-like EGF EGF_2 PF07974.8 EGC32732.1 - 0.011 15.9 8.5 0.011 15.9 5.9 3.9 3 0 0 3 3 3 0 EGF-like domain MASE2 PF05230.6 EGC32733.1 - 0.032 14.1 2.2 0.13 12.2 0.0 3.0 3 0 0 3 3 3 0 MASE2 domain DUF4500 PF14937.1 EGC32733.1 - 0.051 13.4 0.1 0.18 11.6 0.1 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4500) Baculo_11_kDa PF06143.6 EGC32733.1 - 5.2 6.5 8.2 3.9 6.9 0.1 3.4 3 0 0 3 3 3 0 Baculovirus 11 kDa family Cyclin PF08613.6 EGC32734.1 - 6.7e-27 94.7 1.0 7.9e-27 94.5 0.7 1.1 1 0 0 1 1 1 1 Cyclin Cyclin_N PF00134.18 EGC32734.1 - 2.7e-10 39.8 0.0 3.3e-10 39.5 0.0 1.1 1 0 0 1 1 1 1 Cyclin, N-terminal domain OmpH PF03938.9 EGC32735.1 - 0.093 12.6 0.0 0.19 11.6 0.0 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Metallophos PF00149.23 EGC32736.1 - 0.0078 15.6 4.5 0.077 12.3 3.1 2.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase SKG6 PF08693.5 EGC32738.1 - 0.083 12.2 5.4 0.15 11.3 3.8 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain CcmH PF03918.9 EGC32738.1 - 0.19 10.7 0.6 4.8 6.1 0.1 2.1 2 0 0 2 2 2 0 Cytochrome C biogenesis protein DUF3442 PF11924.3 EGC32739.1 - 0.0064 16.1 0.0 0.011 15.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3442) TIG PF01833.19 EGC32740.1 - 3.8e-07 30.0 45.1 0.00094 19.1 0.5 7.6 7 1 0 7 7 7 4 IPT/TIG domain SKG6 PF08693.5 EGC32740.1 - 0.00027 20.1 9.8 0.09 12.1 2.4 2.5 2 0 0 2 2 2 2 Transmembrane alpha-helix domain ETRAMP PF09716.5 EGC32740.1 - 0.27 11.2 6.0 0.12 12.3 0.6 3.1 3 0 0 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) EGF_2 PF07974.8 EGC32740.1 - 0.5 10.5 63.1 0.043 13.9 6.6 4.6 4 0 0 4 4 4 0 EGF-like domain LRR_1 PF00560.28 EGC32740.1 - 0.76 10.0 36.6 1.3 9.3 0.0 11.2 11 0 0 11 11 11 0 Leucine Rich Repeat PARP PF00644.15 EGC32742.1 - 1.5e-32 112.6 1.4 7.1e-32 110.5 1.0 2.2 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain VIT PF08487.5 EGC32742.1 - 3.5e-28 97.6 0.0 9.1e-28 96.3 0.0 1.8 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA_3 PF13768.1 EGC32742.1 - 5.8e-18 65.0 0.0 1.1e-17 64.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain 14-3-3 PF00244.15 EGC32742.1 - 6.1e-15 54.9 6.6 6.1e-15 54.9 4.6 2.3 2 0 0 2 2 2 1 14-3-3 protein VWA PF00092.23 EGC32742.1 - 2.3e-12 46.9 0.0 7.1e-12 45.4 0.0 1.9 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGC32742.1 - 6.1e-11 41.6 0.0 1.3e-10 40.5 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain Ribosomal_60s PF00428.14 EGC32742.1 - 1.3e-08 35.1 24.1 0.039 14.3 0.4 6.8 7 0 0 7 7 7 4 60s Acidic ribosomal protein BRCT PF00533.21 EGC32742.1 - 1.7e-06 28.1 0.2 8.3e-06 25.8 0.1 2.4 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain WH2 PF02205.15 EGC32742.1 - 0.025 14.1 0.2 0.13 11.8 0.0 2.3 2 0 0 2 2 2 0 WH2 motif RNA_pol_Rpb1_R PF05001.8 EGC32742.1 - 0.2 11.8 69.8 0.51 10.5 10.5 5.3 1 1 4 6 6 6 0 RNA polymerase Rpb1 C-terminal repeat UEV PF05743.8 EGC32743.1 - 3.2e-28 97.8 0.3 6.2e-28 96.9 0.2 1.5 1 0 0 1 1 1 1 UEV domain Vps23_core PF09454.5 EGC32743.1 - 9.1e-26 89.2 0.8 1.9e-25 88.2 0.0 1.9 2 0 0 2 2 2 1 Vps23 core domain FlxA PF14282.1 EGC32743.1 - 0.17 11.8 30.0 0.16 11.8 5.3 2.7 2 0 0 2 2 2 0 FlxA-like protein HXXSHH PF07586.6 EGC32743.1 - 0.78 8.6 8.7 0.49 9.2 0.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1552) Corona_S2 PF01601.11 EGC32743.1 - 1.9 6.4 10.0 0.14 10.2 2.7 2.0 1 1 2 3 3 3 0 Coronavirus S2 glycoprotein APG6 PF04111.7 EGC32743.1 - 2.1 7.2 16.9 0.68 8.9 4.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 BLOC1_2 PF10046.4 EGC32743.1 - 3.7 7.7 13.6 0.075 13.1 3.5 2.5 2 1 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 SapB_1 PF05184.10 EGC32743.1 - 9.6 6.1 9.7 2.8 7.8 0.1 3.8 4 0 0 4 4 4 0 Saposin-like type B, region 1 DUF607 PF04678.8 EGC32744.1 - 1.9e-47 161.4 1.6 2e-47 161.4 0.3 1.6 1 1 1 2 2 2 1 Protein of unknown function, DUF607 Sipho_Gp157 PF05565.6 EGC32744.1 - 0.017 14.6 0.6 0.017 14.6 0.4 1.7 2 0 0 2 2 2 0 Siphovirus Gp157 DUF4145 PF13643.1 EGC32744.1 - 0.058 13.2 2.0 0.064 13.1 0.1 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4145) Pedibin PF08182.6 EGC32744.1 - 0.52 9.8 8.5 4.4 6.8 0.3 2.5 2 0 0 2 2 2 0 Pedibin/Hym-346 family TMF_DNA_bd PF12329.3 EGC32744.1 - 2.7 7.8 12.8 2.3 8.1 0.9 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding TAP_C PF03943.8 EGC32745.1 - 8e-11 41.1 1.2 5.8e-10 38.4 0.4 2.6 3 0 0 3 3 3 1 TAP C-terminal domain LRR_4 PF12799.2 EGC32745.1 - 0.0001 21.8 1.1 0.03 13.9 0.7 3.1 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) UBA_4 PF14555.1 EGC32745.1 - 0.0068 15.9 0.0 0.015 14.8 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain LRR_9 PF14580.1 EGC32745.1 - 0.02 14.4 0.0 0.055 13.0 0.0 1.5 1 1 0 1 1 1 0 Leucine-rich repeat LRR_1 PF00560.28 EGC32745.1 - 0.054 13.5 3.2 4.2 7.7 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat Ku PF02735.11 EGC32746.1 - 3e-47 160.6 0.1 9.6e-47 158.9 0.0 1.9 2 0 0 2 2 2 1 Ku70/Ku80 beta-barrel domain Ku_N PF03731.10 EGC32746.1 - 1e-44 152.6 8.1 1e-44 152.6 5.6 1.6 2 0 0 2 2 2 1 Ku70/Ku80 N-terminal alpha/beta domain Ku_C PF03730.9 EGC32746.1 - 8.4e-08 32.6 0.3 3.6e-07 30.6 0.2 2.2 1 0 0 1 1 1 1 Ku70/Ku80 C-terminal arm VWA_2 PF13519.1 EGC32746.1 - 2.8e-06 27.5 0.0 3e-05 24.1 0.0 2.2 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA PF00092.23 EGC32746.1 - 3e-05 23.8 0.7 0.00013 21.7 0.3 2.1 1 1 0 1 1 1 1 von Willebrand factor type A domain Toprim_3 PF13362.1 EGC32746.1 - 0.068 13.4 0.0 0.25 11.6 0.0 2.0 1 1 0 1 1 1 0 Toprim domain Ank_2 PF12796.2 EGC32747.1 - 4.2e-30 103.9 1.2 1.4e-09 38.1 0.1 3.9 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC32747.1 - 1.1e-26 91.2 1.3 3.7e-07 29.6 0.0 6.1 5 1 1 6 6 6 5 Ankyrin repeat Ank_3 PF13606.1 EGC32747.1 - 4.2e-21 72.9 3.8 0.00044 20.2 0.0 6.1 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EGC32747.1 - 1.8e-20 72.8 11.6 3.5e-06 27.3 0.0 6.2 2 1 4 6 6 6 4 Ankyrin repeats (many copies) RGS PF00615.14 EGC32747.1 - 1.2e-17 64.0 5.7 2.6e-12 46.8 0.4 3.4 3 0 0 3 3 3 3 Regulator of G protein signaling domain Ank_5 PF13857.1 EGC32747.1 - 7.7e-16 57.7 11.5 1.3e-06 28.4 0.1 6.1 4 1 3 7 7 7 4 Ankyrin repeats (many copies) zf-TRAF PF02176.13 EGC32748.1 - 1.2e-12 48.0 7.5 1.2e-12 48.0 5.2 4.5 2 1 3 5 5 5 2 TRAF-type zinc finger MATH PF00917.21 EGC32748.1 - 4.1e-07 30.2 1.6 9.8e-07 29.0 1.1 1.8 1 0 0 1 1 1 1 MATH domain Sina PF03145.11 EGC32748.1 - 2.1 7.9 24.3 0.2 11.2 1.7 3.7 2 1 2 4 4 4 0 Seven in absentia protein family Mlo PF03094.10 EGC32749.1 - 0.02 13.0 4.0 0.027 12.6 2.8 1.1 1 0 0 1 1 1 0 Mlo family DUF2755 PF10954.3 EGC32749.1 - 0.072 12.8 0.0 0.14 11.9 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2755) FAD_binding_1 PF00667.15 EGC32751.1 - 4e-30 104.9 2.3 5.2e-30 104.5 0.2 2.3 2 1 0 2 2 2 1 FAD binding domain NAD_binding_1 PF00175.16 EGC32751.1 - 2.6e-14 53.7 0.1 1.2e-13 51.5 0.0 2.2 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Mem_trans PF03547.13 EGC32751.1 - 0.29 9.4 5.4 0.55 8.4 3.7 1.4 1 0 0 1 1 1 0 Membrane transport protein Peptidase_S24 PF00717.18 EGC32751.1 - 3.4 7.3 8.6 0.19 11.4 0.1 3.1 3 0 0 3 3 3 0 Peptidase S24-like UPF0547 PF10571.4 EGC32753.1 - 3.2 7.5 10.0 0.42 10.3 1.6 2.5 3 0 0 3 3 3 0 Uncharacterised protein family UPF0547 zf-piccolo PF05715.8 EGC32753.1 - 6.8 6.7 7.4 22 5.1 0.1 2.9 2 1 1 3 3 3 0 Piccolo Zn-finger FNIP PF05725.7 EGC32754.1 - 4.5e-21 74.5 30.7 1.3e-06 28.2 0.0 9.2 5 2 6 11 11 11 9 FNIP Repeat zf-B_box PF00643.19 EGC32754.1 - 9.8e-06 25.3 6.2 2e-05 24.3 4.3 1.5 1 0 0 1 1 1 1 B-box zinc finger Octopine_DH PF02317.12 EGC32754.1 - 0.058 13.0 1.0 0.12 12.0 0.7 1.5 1 0 0 1 1 1 0 NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain Atrophin-1 PF03154.10 EGC32754.1 - 0.13 10.3 9.2 0.18 9.9 6.4 1.1 1 0 0 1 1 1 0 Atrophin-1 family Prog_receptor PF02161.10 EGC32754.1 - 1.3 7.7 7.5 1.9 7.2 5.2 1.1 1 0 0 1 1 1 0 Progesterone receptor p450 PF00067.17 EGC32755.1 - 7.1e-49 166.5 0.0 8e-49 166.4 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DDE_Tnp_IS240 PF13610.1 EGC32757.1 - 2.6 8.0 8.4 3.5 7.6 5.7 1.3 1 1 0 1 1 1 0 DDE domain Ribosomal_S7 PF00177.16 EGC32758.1 - 3.2e-35 120.8 0.2 3.8e-35 120.6 0.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S7p/S5e FNIP PF05725.7 EGC32759.1 - 2.5e-53 177.7 32.3 3.3e-16 58.9 0.3 5.7 4 2 1 5 5 5 5 FNIP Repeat DUF1769 PF08588.5 EGC32759.1 - 6e-05 22.9 12.9 1.6 8.7 0.0 6.6 2 1 5 7 7 7 3 Protein of unknown function (DUF1769) Gryzun PF07919.7 EGC32760.1 - 9.6e-70 235.4 26.6 1.8e-69 234.5 18.4 1.5 1 0 0 1 1 1 1 Gryzun, putative trafficking through Golgi Foie-gras_1 PF11817.3 EGC32760.1 - 4.7e-38 131.0 0.4 8.7e-38 130.1 0.3 1.4 1 0 0 1 1 1 1 Foie gras liver health family 1 Gryzun-like PF12742.2 EGC32760.1 - 0.00025 20.7 0.1 0.00062 19.5 0.1 1.7 1 0 0 1 1 1 1 Gryzun, putative Golgi trafficking TRAPPC10 PF12584.3 EGC32760.1 - 0.00072 19.0 0.0 0.0026 17.2 0.0 1.9 1 0 0 1 1 1 1 Trafficking protein particle complex subunit 10, TRAPPC10 TPR_1 PF00515.23 EGC32760.1 - 0.11 12.1 1.4 0.31 10.7 0.9 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat tRNA-synt_1e PF01406.14 EGC32761.1 - 5.5e-130 432.8 0.2 9.7e-130 432.0 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGC32761.1 - 6.1e-13 48.1 1.1 1.7e-05 23.6 0.2 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGC32761.1 - 0.00023 19.2 0.1 0.00023 19.2 0.1 3.2 3 0 0 3 3 3 1 tRNA synthetases class I (I, L, M and V) DALR_2 PF09190.6 EGC32761.1 - 0.0065 16.7 0.0 0.0065 16.7 0.0 2.2 2 0 0 2 2 2 1 DALR domain tRNA-synt_1c PF00749.16 EGC32761.1 - 0.014 14.1 0.0 0.014 14.1 0.0 2.8 3 0 0 3 3 3 0 tRNA synthetases class I (E and Q), catalytic domain AAA PF00004.24 EGC32762.1 - 1.1e-20 74.1 0.0 1.9e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BCS1_N PF08740.6 EGC32762.1 - 2.3e-20 73.0 0.1 6.7e-20 71.4 0.0 1.8 2 0 0 2 2 2 1 BCS1 N terminal AAA_11 PF13086.1 EGC32762.1 - 1.5e-05 24.6 0.0 2.4e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGC32762.1 - 4.5e-05 23.5 0.1 0.014 15.5 0.0 2.8 2 0 0 2 2 2 1 RNA helicase AAA_25 PF13481.1 EGC32762.1 - 7.1e-05 22.2 0.0 0.00013 21.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGC32762.1 - 0.0002 21.1 0.0 0.0007 19.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGC32762.1 - 0.0013 17.8 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC32762.1 - 0.0027 17.8 0.0 0.0062 16.6 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC32762.1 - 0.0029 18.4 1.3 0.045 14.5 0.3 2.8 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC32762.1 - 0.004 16.8 0.0 0.0089 15.7 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_21 PF13304.1 EGC32762.1 - 0.016 15.2 0.2 0.016 15.2 0.1 3.3 3 1 0 3 3 3 0 AAA domain AAA_24 PF13479.1 EGC32762.1 - 0.029 13.9 0.1 0.083 12.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC32762.1 - 0.029 14.3 0.1 0.1 12.5 0.0 1.8 1 1 0 1 1 1 0 AAA ATPase domain AAA_18 PF13238.1 EGC32762.1 - 0.048 13.9 2.5 0.74 10.1 0.0 2.6 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGC32762.1 - 0.08 12.0 0.0 0.17 10.9 0.0 1.4 1 0 0 1 1 1 0 Zeta toxin AAA_29 PF13555.1 EGC32762.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC32762.1 - 0.14 12.4 1.2 0.22 11.8 0.0 1.9 2 1 0 2 2 1 0 ABC transporter IstB_IS21 PF01695.12 EGC32762.1 - 0.15 11.5 0.2 1.1 8.6 0.2 2.1 1 1 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EGC32762.1 - 8.1 6.7 13.0 8.2 6.6 6.4 2.5 2 1 0 2 2 2 0 AAA domain FNIP PF05725.7 EGC32763.1 - 1.5e-108 354.5 37.3 3.6e-17 62.0 0.1 8.5 5 1 5 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.8 EGC32763.1 - 9.7e-05 22.2 0.0 6.5 6.7 0.0 5.2 4 2 2 6 6 6 2 Phage minor tail protein DUF1769 PF08588.5 EGC32763.1 - 0.025 14.5 27.3 5.5 7.0 0.1 9.2 3 3 7 11 11 11 0 Protein of unknown function (DUF1769) SSP160 PF06933.6 EGC32764.1 - 0.0081 14.2 6.5 0.011 13.7 4.5 1.1 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC32764.1 - 0.1 12.3 14.2 0.17 11.6 9.9 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2951 PF11166.3 EGC32764.1 - 1.3 8.8 12.5 0.045 13.5 2.9 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2951) Arc_PepC_II PF06847.6 EGC32764.1 - 1.9 8.9 4.5 3.9 7.9 0.3 3.3 2 2 0 2 2 2 0 Archaeal Peptidase A24 C-terminus Type II DTHCT PF08070.6 EGC32764.1 - 2.7 8.7 5.3 15 6.3 0.3 2.5 2 0 0 2 2 2 0 DTHCT (NUC029) region Glyco_hydro_47 PF01532.15 EGC32765.1 - 2.7e-133 444.9 0.3 3.5e-133 444.5 0.2 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Tetraspannin PF00335.15 EGC32765.1 - 0.005 16.1 2.6 0.0093 15.2 1.8 1.5 1 0 0 1 1 1 1 Tetraspanin family Neur_chan_memb PF02932.11 EGC32765.1 - 0.35 10.7 1.8 0.59 9.9 1.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 EGC32765.1 - 1.2 7.6 4.2 1.6 7.1 2.9 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein PUF PF00806.14 EGC32766.1 - 5.7e-58 189.2 17.8 5.8e-09 34.9 0.5 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat zf-CCCH PF00642.19 EGC32766.1 - 7.2e-05 22.3 2.8 0.00018 21.1 1.9 1.7 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) DUF374 PF04028.8 EGC32766.1 - 0.16 11.2 0.0 2 7.7 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF374) V_ATPase_I PF01496.14 EGC32766.1 - 4.4 5.0 9.1 7.2 4.3 6.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family IncA PF04156.9 EGC32766.1 - 10 5.6 30.2 1.6 8.3 17.6 2.1 2 0 0 2 2 2 0 IncA protein PH_8 PF15409.1 EGC32768.1 - 0.077 13.0 9.4 0.049 13.7 1.2 3.8 3 1 0 3 3 3 0 Pleckstrin homology domain UPF0203 PF05254.7 EGC32769.1 - 0.0001 22.0 0.8 0.014 15.2 0.2 2.1 1 1 1 2 2 2 2 Uncharacterised protein family (UPF0203) CHCH PF06747.8 EGC32769.1 - 0.001 18.8 0.8 0.0015 18.3 0.6 1.3 1 0 0 1 1 1 1 CHCH domain Ndufs5 PF10200.4 EGC32769.1 - 0.028 14.3 0.6 0.14 12.1 0.3 1.8 1 1 1 2 2 2 0 NADH:ubiquinone oxidoreductase, NDUFS5-15kDa PRELI PF04707.9 EGC32770.1 - 2.6e-49 166.7 0.0 4e-49 166.1 0.0 1.3 1 0 0 1 1 1 1 PRELI-like family Fic_N PF13784.1 EGC32770.1 - 0.0053 16.5 0.0 2.1 8.2 0.0 2.3 2 0 0 2 2 2 2 Fic/DOC family N-terminal Peptidase_M24 PF00557.19 EGC32771.1 - 3.1e-38 131.4 0.2 4.6e-38 130.8 0.1 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Creatinase_N PF01321.13 EGC32771.1 - 3.1e-32 111.8 0.0 3.4e-23 82.5 0.0 2.5 2 0 0 2 2 2 2 Creatinase/Prolidase N-terminal domain TFIIE_alpha PF02002.12 EGC32771.1 - 0.022 14.2 0.3 0.066 12.7 0.2 1.8 1 0 0 1 1 1 0 TFIIE alpha subunit DUF2934 PF11154.3 EGC32771.1 - 0.085 12.2 0.1 0.15 11.4 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2934) FNIP PF05725.7 EGC32772.1 - 1.5e-25 88.8 63.7 5.1e-09 35.9 1.9 11.9 7 4 6 13 13 13 11 FNIP Repeat MHCassoc_trimer PF08831.5 EGC32772.1 - 0.12 12.2 1.0 3.5 7.5 0.1 3.3 3 0 0 3 3 3 0 Class II MHC-associated invariant chain trimerisation domain Pkinase_Tyr PF07714.12 EGC32773.1 - 6.4e-50 169.6 0.0 1.4e-49 168.5 0.0 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC32773.1 - 1e-43 149.3 0.0 2.3e-43 148.2 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 EGC32773.1 - 1.4e-43 148.8 1.2 5.3e-43 146.9 0.0 2.5 2 1 0 2 2 2 1 RasGEF domain cNMP_binding PF00027.24 EGC32773.1 - 6.8e-28 96.3 0.2 2.6e-14 52.7 0.0 3.2 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Ras PF00071.17 EGC32773.1 - 1.1e-13 50.8 0.5 2.5e-13 49.7 0.4 1.6 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32773.1 - 3.6e-12 46.8 0.2 1.8e-11 44.5 0.1 2.4 1 0 0 1 1 1 1 Miro-like protein LRR_4 PF12799.2 EGC32773.1 - 1.9e-11 43.2 28.4 2.4e-05 23.8 3.8 5.0 2 1 3 5 5 5 3 Leucine Rich repeats (2 copies) GRAM PF02893.15 EGC32773.1 - 1.4e-10 40.5 2.2 1.5e-10 40.4 0.2 2.1 2 0 0 2 2 2 1 GRAM domain RasGEF_N PF00618.15 EGC32773.1 - 1.1e-09 38.3 0.4 6.8e-09 35.7 0.2 2.4 1 0 0 1 1 1 1 RasGEF N-terminal motif DEP PF00610.16 EGC32773.1 - 3.4e-08 33.1 0.0 1.1e-07 31.5 0.0 2.0 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) APH PF01636.18 EGC32773.1 - 0.0011 18.7 0.0 0.0019 17.9 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family AAA_18 PF13238.1 EGC32773.1 - 0.025 14.8 0.1 0.14 12.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC32773.1 - 0.18 11.7 0.0 0.54 10.2 0.0 1.8 1 0 0 1 1 1 0 AAA ATPase domain LRR_7 PF13504.1 EGC32773.1 - 0.88 10.0 14.7 34 5.2 0.3 6.5 6 0 0 6 6 6 0 Leucine rich repeat SSP160 PF06933.6 EGC32774.1 - 0.6 8.0 17.7 0.63 7.9 12.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Chorion_3 PF05387.6 EGC32774.1 - 2.5 7.4 6.4 2.8 7.3 4.4 1.0 1 0 0 1 1 1 0 Chorion family 3 DUF870 PF05912.6 EGC32775.1 - 0.5 10.1 3.2 2.6 7.9 1.0 2.1 1 1 1 2 2 2 0 Caenorhabditis elegans protein of unknown function (DUF870) P-II PF00543.17 EGC32778.1 - 0.041 14.3 0.1 0.068 13.6 0.1 1.3 1 0 0 1 1 1 0 Nitrogen regulatory protein P-II DUF3586 PF12131.3 EGC32778.1 - 0.13 12.3 4.9 1.2 9.2 0.2 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) Abhydrolase_6 PF12697.2 EGC32779.1 - 2e-25 90.0 0.0 2.4e-25 89.7 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC32779.1 - 2.8e-25 89.2 0.0 6.5e-24 84.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC32779.1 - 7.9e-13 48.3 0.0 1e-12 47.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EGC32779.1 - 3.2e-05 22.5 0.0 3.9e-05 22.2 0.0 1.2 1 0 0 1 1 1 1 Ndr family BAAT_C PF08840.6 EGC32779.1 - 0.0014 18.3 0.0 0.0079 15.9 0.0 2.0 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Esterase PF00756.15 EGC32779.1 - 0.015 14.7 0.0 0.015 14.7 0.0 1.3 1 1 0 1 1 1 0 Putative esterase DUF915 PF06028.6 EGC32779.1 - 0.015 14.3 0.2 0.03 13.4 0.0 1.5 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) PGAP1 PF07819.8 EGC32779.1 - 0.058 12.9 0.1 0.12 11.9 0.0 1.5 2 0 0 2 2 2 0 PGAP1-like protein DLH PF01738.13 EGC32779.1 - 0.075 12.3 0.0 5.8 6.1 0.0 2.3 2 1 0 2 2 2 0 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGC32779.1 - 0.077 12.4 0.0 0.39 10.1 0.0 1.9 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DUF2048 PF09752.4 EGC32779.1 - 0.08 11.8 0.1 0.42 9.4 0.0 1.9 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) FSH1 PF03959.8 EGC32779.1 - 0.085 12.2 0.1 0.12 11.8 0.0 1.6 1 1 0 1 1 1 0 Serine hydrolase (FSH1) Thioesterase PF00975.15 EGC32779.1 - 0.098 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 Thioesterase domain DUF900 PF05990.7 EGC32779.1 - 0.14 11.4 0.0 0.21 10.8 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Lipase_3 PF01764.20 EGC32779.1 - 0.14 11.7 0.1 0.35 10.4 0.0 1.6 2 0 0 2 2 2 0 Lipase (class 3) Mucin PF01456.12 EGC32780.1 - 0.29 10.8 13.2 0.43 10.3 9.2 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGC32780.1 - 2.8 7.7 10.2 5.8 6.6 7.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGC32780.1 - 6.2 4.6 10.6 8.2 4.2 7.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 RhoGEF PF00621.15 EGC32781.1 - 9.8e-49 165.6 4.4 9.8e-49 165.6 3.1 2.2 2 0 0 2 2 2 1 RhoGEF domain RNA_pol_I_A49 PF06870.7 EGC32782.1 - 8e-41 139.8 7.7 1.1e-40 139.4 5.4 1.1 1 0 0 1 1 1 1 A49-like RNA polymerase I associated factor FNIP PF05725.7 EGC32783.1 - 1.7e-38 130.3 36.4 7e-10 38.6 0.1 7.5 4 2 4 8 8 8 7 FNIP Repeat Pox_Ag35 PF03286.9 EGC32783.1 - 6.9 6.1 23.7 0.13 11.8 11.2 1.8 2 0 0 2 2 2 0 Pox virus Ag35 surface protein FNIP PF05725.7 EGC32784.1 - 2.1e-87 286.8 78.4 2.2e-12 46.7 0.2 12.3 6 2 8 15 15 15 13 FNIP Repeat DUF1769 PF08588.5 EGC32784.1 - 0.0027 17.5 6.5 0.98 9.4 0.1 5.6 6 2 1 7 7 7 2 Protein of unknown function (DUF1769) MYT1 PF08474.6 EGC32784.1 - 0.1 12.0 0.0 0.19 11.1 0.0 1.4 1 0 0 1 1 1 0 Myelin transcription factor 1 Med30 PF11315.3 EGC32785.1 - 0.00076 19.6 1.0 0.00083 19.5 0.7 1.1 1 0 0 1 1 1 1 Mediator complex subunit 30 ThylakoidFormat PF11264.3 EGC32785.1 - 0.0021 17.7 1.8 0.0073 15.9 0.5 1.9 1 1 1 2 2 2 1 Thylakoid formation protein DUF3914 PF13053.1 EGC32785.1 - 0.016 15.3 6.2 0.019 15.1 3.8 1.5 1 1 1 2 2 2 0 Protein of unknown function (DUF3914) Luteo_P1-P2 PF08467.5 EGC32785.1 - 0.017 13.9 1.0 0.017 13.9 0.7 1.0 1 0 0 1 1 1 0 Luteovirus RNA polymerase P1-P2/replicase GET2 PF08690.5 EGC32785.1 - 0.024 13.8 3.4 0.027 13.7 2.4 1.0 1 0 0 1 1 1 0 GET complex subunit GET2 DUF3393 PF11873.3 EGC32785.1 - 0.047 13.2 2.8 0.054 12.9 1.9 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3393) HeLo PF14479.1 EGC32785.1 - 0.054 13.2 1.8 0.059 13.1 1.3 1.1 1 0 0 1 1 1 0 Prion-inhibition and propagation Allexi_40kDa PF05549.6 EGC32785.1 - 0.058 12.6 1.7 0.065 12.5 1.2 1.0 1 0 0 1 1 1 0 Allexivirus 40kDa protein zf-ZPR1 PF03367.8 EGC32785.1 - 0.12 11.5 0.9 0.14 11.3 0.6 1.1 1 0 0 1 1 1 0 ZPR1 zinc-finger domain GAT PF03127.9 EGC32785.1 - 0.22 11.4 2.4 0.47 10.4 1.7 1.6 1 1 0 1 1 1 0 GAT domain Wx5_PLAF3D7 PF09688.5 EGC32785.1 - 0.24 11.3 5.0 0.36 10.7 3.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (Wx5_PLAF3D7) DUF4200 PF13863.1 EGC32785.1 - 0.41 10.5 5.6 0.48 10.3 3.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) TMPIT PF07851.8 EGC32785.1 - 0.48 9.4 4.4 0.54 9.2 3.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein V-SNARE PF05008.10 EGC32785.1 - 0.68 10.1 5.0 0.36 11.0 1.8 1.8 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus IncA PF04156.9 EGC32785.1 - 0.82 9.2 5.3 0.94 9.0 3.7 1.0 1 0 0 1 1 1 0 IncA protein PGAP1 PF07819.8 EGC32786.1 - 2.7e-68 229.9 0.1 2.7e-68 229.9 0.1 2.0 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGC32786.1 - 0.00083 19.1 0.0 0.0017 18.1 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC32786.1 - 0.0028 17.5 0.0 0.0046 16.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGC32786.1 - 0.0038 16.6 0.0 0.061 12.7 0.0 2.2 2 0 0 2 2 2 1 Putative esterase Abhydrolase_3 PF07859.8 EGC32786.1 - 0.1 12.1 0.0 0.27 10.7 0.0 1.6 2 0 0 2 2 2 0 alpha/beta hydrolase fold B56 PF01603.15 EGC32787.1 - 1.8e-151 504.4 11.9 2.4e-151 503.9 8.2 1.1 1 0 0 1 1 1 1 Protein phosphatase 2A regulatory B subunit (B56 family) FTCD_C PF04961.7 EGC32787.1 - 0.14 11.5 0.1 0.23 10.8 0.1 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase DUF3299 PF11736.3 EGC32787.1 - 5.5 6.8 9.2 9.1 6.1 0.0 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF3299) PseudoU_synth_2 PF00849.17 EGC32788.1 - 1.7e-25 89.7 21.6 2e-13 50.4 0.0 4.8 3 2 0 3 3 3 2 RNA pseudouridylate synthase S4 PF01479.20 EGC32788.1 - 0.0063 15.9 1.0 0.014 14.8 0.2 1.9 2 0 0 2 2 2 1 S4 domain DUF3413 PF11893.3 EGC32788.1 - 0.036 12.9 4.7 0.12 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3413) Pkinase PF00069.20 EGC32789.1 - 3.4e-55 186.9 0.0 3.4e-55 186.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC32789.1 - 7.3e-51 172.7 0.0 1e-50 172.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC32789.1 - 0.17 10.8 0.0 0.28 10.2 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ABC2_membrane PF01061.19 EGC32790.1 - 2.7e-87 291.3 55.6 2.5e-46 157.4 15.1 2.4 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC32790.1 - 6.9e-39 133.2 0.0 2.7e-19 69.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGC32790.1 - 4.4e-21 74.4 11.1 2e-16 59.5 0.1 3.4 3 0 0 3 3 2 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGC32790.1 - 1.4e-12 47.3 61.1 8e-08 31.6 15.3 3.8 2 2 0 2 2 2 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EGC32790.1 - 6.8e-10 38.8 0.1 1.5e-09 37.7 0.1 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EGC32790.1 - 5.1e-07 29.0 0.1 6.1e-05 22.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC32790.1 - 4.8e-06 26.0 0.5 0.0028 17.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC32790.1 - 8.6e-05 22.6 0.2 0.085 12.9 0.1 2.7 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC32790.1 - 9.6e-05 21.8 0.3 0.0023 17.3 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_21 PF13304.1 EGC32790.1 - 0.00012 22.1 4.7 0.16 11.8 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_18 PF13238.1 EGC32790.1 - 0.00018 21.8 1.4 0.57 10.4 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGC32790.1 - 0.00094 19.2 0.0 0.29 11.1 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGC32790.1 - 0.0018 19.1 0.1 0.61 10.9 0.0 3.1 3 0 0 3 3 2 1 AAA domain cobW PF02492.14 EGC32790.1 - 0.0019 17.6 0.2 0.07 12.5 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGC32790.1 - 0.0046 16.6 1.4 3.8 7.1 0.0 3.1 3 0 0 3 3 3 2 Archaeal ATPase MMR_HSR1 PF01926.18 EGC32790.1 - 0.019 14.9 0.0 9.2 6.2 0.0 2.7 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGC32790.1 - 0.029 14.2 0.0 0.58 10.1 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit FtsK_SpoIIIE PF01580.13 EGC32790.1 - 0.034 13.6 0.1 4.2 6.7 0.0 2.4 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_33 PF13671.1 EGC32790.1 - 0.049 13.5 0.3 1 9.2 0.2 2.4 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGC32790.1 - 0.062 13.2 1.4 0.58 10.1 0.3 2.6 3 0 0 3 3 2 0 AAA domain UPF0079 PF02367.12 EGC32790.1 - 0.076 12.6 0.2 0.68 9.5 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGC32790.1 - 0.086 12.3 0.3 1.2 8.6 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_19 PF13245.1 EGC32790.1 - 0.11 12.2 0.0 12 5.7 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain NACHT PF05729.7 EGC32790.1 - 0.18 11.4 0.3 4.8 6.8 0.3 2.4 2 0 0 2 2 2 0 NACHT domain AAA_30 PF13604.1 EGC32790.1 - 0.41 10.2 0.1 4.6 6.7 0.1 2.2 2 0 0 2 2 2 0 AAA domain Myosin_HC-like PF07058.6 EGC32790.1 - 0.45 9.5 1.2 0.71 8.9 0.8 1.2 1 0 0 1 1 1 0 Myosin II heavy chain-like AAA PF00004.24 EGC32790.1 - 0.91 9.7 2.5 4.6 7.4 0.1 3.1 3 1 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Sel1 PF08238.7 EGC32791.1 - 4.4e-10 39.8 2.8 0.0042 17.6 0.1 4.8 5 0 0 5 5 5 3 Sel1 repeat TPR_11 PF13414.1 EGC32791.1 - 0.006 16.2 2.8 1.1 8.9 0.0 3.4 3 0 0 3 3 3 1 TPR repeat TPR_1 PF00515.23 EGC32791.1 - 0.016 14.7 4.2 0.4 10.3 0.8 3.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32791.1 - 0.45 10.5 8.7 0.55 10.2 0.5 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32791.1 - 7.4 6.5 9.6 2.8 7.9 2.3 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TBCC PF07986.7 EGC32792.1 - 2.1e-29 101.3 4.9 2.1e-29 101.3 3.4 2.3 2 1 0 2 2 2 1 Tubulin binding cofactor C Fzo_mitofusin PF04799.8 EGC32792.1 - 0.011 15.1 7.9 0.011 15.1 5.5 1.9 1 1 0 1 1 1 0 fzo-like conserved region Halogen_Hydrol PF10112.4 EGC32792.1 - 0.52 9.6 10.2 0.18 11.1 3.3 2.4 2 1 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein LETM1 PF07766.8 EGC32792.1 - 2.6 7.0 15.4 4 6.3 10.7 1.2 1 0 0 1 1 1 0 LETM1-like protein zf-RING_4 PF14570.1 EGC32793.1 - 3.7e-19 68.0 12.5 7.2e-19 67.1 8.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain RRM_5 PF13893.1 EGC32793.1 - 6.9e-09 35.4 0.1 1.3e-08 34.5 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC32793.1 - 6e-08 32.2 0.0 1.3e-07 31.1 0.0 1.6 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-C3HC4_3 PF13920.1 EGC32793.1 - 1.7e-07 30.8 8.3 3.7e-07 29.7 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC32793.1 - 4.3e-07 29.6 9.6 4.3e-07 29.6 6.7 2.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGC32793.1 - 3.3e-05 23.4 10.1 9e-05 22.0 7.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32793.1 - 5.5e-05 23.0 10.9 0.00013 21.9 7.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EGC32793.1 - 0.00027 20.2 1.0 0.00036 19.8 0.7 1.2 1 0 0 1 1 1 1 Rtf2 RING-finger Rad50_zn_hook PF04423.9 EGC32793.1 - 0.0075 15.7 2.4 1.9 7.9 0.1 2.4 2 0 0 2 2 2 2 Rad50 zinc hook motif zf-RING_5 PF14634.1 EGC32793.1 - 0.0088 15.7 10.3 0.019 14.6 7.2 1.6 1 0 0 1 1 1 1 zinc-RING finger domain RRM_6 PF14259.1 EGC32793.1 - 0.027 14.4 0.0 0.055 13.4 0.0 1.6 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-UDP PF14569.1 EGC32793.1 - 0.028 14.1 10.2 0.024 14.3 5.3 2.2 2 1 0 2 2 2 0 Zinc-binding RING-finger Baculo_IE-1 PF05290.6 EGC32793.1 - 0.041 13.6 8.4 0.041 13.6 4.2 2.0 2 1 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-C3HC4_4 PF15227.1 EGC32793.1 - 0.13 12.1 10.6 0.97 9.3 7.4 2.4 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC32793.1 - 3.3 7.3 9.5 18 4.9 3.4 2.5 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 cNMP_binding PF00027.24 EGC32794.1 - 3.8e-23 81.0 0.1 9.4e-17 60.6 0.0 2.7 2 0 0 2 2 2 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.22 EGC32794.1 - 7.3e-13 48.6 0.0 3.2e-12 46.5 0.0 2.0 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC32794.1 - 1.9e-12 47.1 0.8 9.8e-12 44.8 0.1 2.4 2 1 1 3 3 3 1 Beta-lactamase superfamily domain PP2C PF00481.16 EGC32795.1 - 3.8e-51 173.9 0.2 1.8e-33 115.9 0.0 3.1 2 1 0 2 2 2 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGC32795.1 - 0.047 13.0 0.1 2.1 7.7 0.0 2.6 3 0 0 3 3 3 0 Protein phosphatase 2C Arm PF00514.18 EGC32796.1 - 1.3e-25 88.2 28.5 0.075 12.8 0.1 17.7 17 1 1 18 18 18 7 Armadillo/beta-catenin-like repeat WW PF00397.21 EGC32796.1 - 1.7e-17 62.9 8.0 1.5e-10 40.7 0.3 2.5 2 0 0 2 2 2 2 WW domain HEAT_2 PF13646.1 EGC32796.1 - 1.3e-12 47.8 1.5 0.016 15.4 0.0 7.8 8 1 1 9 9 9 2 HEAT repeats HEAT PF02985.17 EGC32796.1 - 5.4e-05 22.9 6.2 4.3 7.6 0.0 7.7 8 0 0 8 8 8 1 HEAT repeat FYVE PF01363.16 EGC32796.1 - 0.016 15.0 1.0 0.016 15.0 0.7 2.2 2 0 0 2 2 2 0 FYVE zinc finger HEAT_EZ PF13513.1 EGC32796.1 - 0.046 14.2 0.1 27 5.4 0.0 5.2 5 0 0 5 5 5 0 HEAT-like repeat V-ATPase_H_C PF11698.3 EGC32796.1 - 0.42 10.5 14.9 11 5.9 0.1 7.0 5 2 3 8 8 8 0 V-ATPase subunit H 3HCDH_N PF02737.13 EGC32797.1 - 4.7e-62 208.8 4.4 5.7e-62 208.5 3.1 1.1 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 3HCDH PF00725.17 EGC32797.1 - 2e-31 108.2 0.0 4.3e-31 107.1 0.0 1.6 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain NAD_Gly3P_dh_N PF01210.18 EGC32797.1 - 2.9e-06 27.0 1.3 4.6e-06 26.4 0.9 1.3 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus NAD_binding_2 PF03446.10 EGC32797.1 - 3e-05 23.9 1.1 8.9e-05 22.3 0.7 1.8 1 1 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGC32797.1 - 0.0002 20.7 0.3 0.00031 20.1 0.2 1.2 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain F420_oxidored PF03807.12 EGC32797.1 - 0.00023 21.5 1.9 0.00078 19.8 1.3 1.9 1 1 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent ApbA PF02558.11 EGC32797.1 - 0.00032 20.1 0.1 0.00068 19.0 0.0 1.7 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA 2-Hacid_dh_C PF02826.14 EGC32797.1 - 0.00041 19.5 0.6 0.0011 18.2 0.4 1.8 1 1 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGC32797.1 - 0.0019 17.8 0.3 0.0031 17.1 0.2 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase TrkA_N PF02254.13 EGC32797.1 - 0.0021 18.0 0.3 0.0054 16.7 0.1 1.7 1 1 0 1 1 1 1 TrkA-N domain NAD_binding_7 PF13241.1 EGC32797.1 - 0.003 17.7 0.3 0.0053 16.9 0.2 1.3 1 0 0 1 1 1 1 Putative NAD(P)-binding Saccharop_dh PF03435.13 EGC32797.1 - 0.0034 16.4 0.1 0.0047 15.9 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase ThiF PF00899.16 EGC32797.1 - 0.019 14.7 1.5 0.051 13.3 1.1 1.9 1 1 0 1 1 1 0 ThiF family Methyltransf_31 PF13847.1 EGC32797.1 - 0.04 13.4 1.3 0.063 12.8 0.9 1.4 1 1 0 1 1 1 0 Methyltransferase domain DXP_synthase_N PF13292.1 EGC32797.1 - 0.046 12.6 1.3 0.062 12.2 0.9 1.3 1 0 0 1 1 1 0 1-deoxy-D-xylulose-5-phosphate synthase PARP_regulatory PF01358.13 EGC32797.1 - 0.05 12.2 0.1 0.072 11.7 0.1 1.1 1 0 0 1 1 1 0 Poly A polymerase regulatory subunit DAO PF01266.19 EGC32797.1 - 0.079 11.8 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Ldh_1_N PF00056.18 EGC32797.1 - 0.15 11.8 6.3 2.3 8.0 4.3 2.7 1 1 0 1 1 1 0 lactate/malate dehydrogenase, NAD binding domain Shikimate_DH PF01488.15 EGC32797.1 - 0.17 11.9 3.4 1 9.4 1.6 2.2 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase DUF4203 PF13886.1 EGC32799.1 - 2.8e-08 33.4 23.8 3.7e-08 33.0 16.5 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) ERCC4 PF02732.10 EGC32800.1 - 4.3e-13 49.2 3.2 4.5e-13 49.1 0.0 2.8 2 0 0 2 2 2 1 ERCC4 domain zf-C3HC4_3 PF13920.1 EGC32801.1 - 2.6e-09 36.5 7.8 4.3e-09 35.8 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC32801.1 - 3.7e-08 32.8 9.5 6.7e-08 32.0 6.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC32801.1 - 8.8e-08 31.8 9.5 1.5e-07 31.1 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC32801.1 - 4.3e-06 26.7 5.8 9.2e-06 25.6 4.0 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC32801.1 - 4.5e-06 26.5 9.9 7.6e-06 25.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC32801.1 - 0.00059 19.5 9.3 0.001 18.7 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC32801.1 - 0.0084 15.9 9.5 0.041 13.7 6.5 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC32801.1 - 0.028 14.1 3.2 0.081 12.6 2.2 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EGC32801.1 - 0.14 12.0 7.4 2 8.3 5.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 EGC32801.1 - 0.35 10.7 5.4 0.76 9.6 3.7 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC32801.1 - 0.35 10.4 11.3 2.8 7.5 7.8 2.2 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain RabGAP-TBC PF00566.13 EGC32803.1 - 5.3e-53 179.6 3.8 5.3e-53 179.6 2.6 2.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EGC32803.1 - 5.8e-14 52.1 0.0 4.2e-12 46.2 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC32803.1 - 1.2e-11 43.7 0.0 0.00062 19.4 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGC32803.1 - 3.4e-08 33.4 0.0 6e-07 29.5 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC32803.1 - 2e-07 31.3 0.0 6e-05 23.4 0.0 3.4 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32803.1 - 4.5e-06 26.3 0.0 0.055 13.7 0.0 3.9 4 0 0 4 4 4 2 Ankyrin repeat PSS PF03034.10 EGC32804.1 - 4e-117 390.6 9.1 4.8e-117 390.3 6.3 1.1 1 0 0 1 1 1 1 Phosphatidyl serine synthase DUF2363 PF10155.4 EGC32805.1 - 4.7e-49 165.4 7.8 4.7e-49 165.4 5.4 2.1 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2363) RhoGAP PF00620.22 EGC32806.1 - 2.4e-33 114.9 2.3 9.1e-33 113.0 0.3 2.5 2 0 0 2 2 2 1 RhoGAP domain BAR PF03114.13 EGC32806.1 - 4e-08 33.0 7.2 8.6e-08 31.9 5.0 1.5 1 0 0 1 1 1 1 BAR domain BAR_2 PF10455.4 EGC32806.1 - 0.00031 19.7 12.6 0.00034 19.6 7.9 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking GAS PF13851.1 EGC32806.1 - 0.00062 19.0 1.9 0.00062 19.0 1.3 3.3 4 0 0 4 4 4 1 Growth-arrest specific micro-tubule binding Filament PF00038.16 EGC32806.1 - 0.0046 16.4 0.4 0.0046 16.4 0.3 2.5 3 0 0 3 3 3 1 Intermediate filament protein DUF1759 PF03564.10 EGC32806.1 - 0.098 12.4 4.6 0.44 10.3 0.3 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF1759) IMD PF08397.6 EGC32806.1 - 2.6 7.3 11.6 0.5 9.6 1.7 2.8 3 1 0 3 3 3 0 IRSp53/MIM homology domain Gar1 PF04410.9 EGC32807.1 - 2.3e-27 95.3 0.4 2.5e-27 95.2 0.3 1.0 1 0 0 1 1 1 1 Gar1/Naf1 RNA binding region Hid1 PF12722.2 EGC32808.1 - 0.12 10.0 15.2 0.13 9.9 10.6 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein CDK5_activator PF03261.10 EGC32808.1 - 0.33 10.2 14.2 0.43 9.8 9.9 1.2 1 0 0 1 1 1 0 Cyclin-dependent kinase 5 activator protein DUF1675 PF07897.6 EGC32808.1 - 1.2 8.9 13.6 1.5 8.6 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) MRI PF15325.1 EGC32808.1 - 8 7.4 8.0 16 6.5 5.6 1.5 1 0 0 1 1 1 0 Modulator of retrovirus infection Y_phosphatase PF00102.22 EGC32809.1 - 3.6e-72 242.5 0.0 1.4e-71 240.5 0.0 1.8 1 1 0 1 1 1 1 Protein-tyrosine phosphatase DSPc PF00782.15 EGC32809.1 - 6.4e-06 25.7 0.3 1.9e-05 24.2 0.0 1.9 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGC32809.1 - 1.3e-05 25.2 0.1 5.1e-05 23.3 0.0 2.0 2 0 0 2 2 2 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGC32809.1 - 0.015 15.5 0.0 0.034 14.4 0.0 1.7 1 0 0 1 1 1 0 Tyrosine phosphatase family Yeast-kill-tox PF09207.6 EGC32809.1 - 0.047 14.1 0.2 2.5 8.5 0.0 2.5 2 0 0 2 2 2 0 Yeast killer toxin BUD22 PF09073.5 EGC32809.1 - 1.6 7.6 9.0 2.4 7.1 6.2 1.3 1 0 0 1 1 1 0 BUD22 Nop14 PF04147.7 EGC32809.1 - 5.8 4.7 11.1 7.1 4.4 7.7 1.1 1 0 0 1 1 1 0 Nop14-like family SH3BGR PF04908.10 EGC32810.1 - 7.8e-13 48.2 0.3 1.1e-12 47.7 0.2 1.2 1 0 0 1 1 1 1 SH3-binding, glutamic acid-rich protein Glutaredoxin PF00462.19 EGC32810.1 - 1.1e-11 44.5 0.0 1.8e-11 43.8 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin GST_N_3 PF13417.1 EGC32810.1 - 0.0046 17.1 0.0 0.0062 16.7 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Med15 PF09606.5 EGC32811.1 - 5.4e-06 24.9 68.8 7.3e-06 24.4 47.7 1.4 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal ABC2_membrane PF01061.19 EGC32812.1 - 1.3e-90 302.1 60.0 1.4e-49 168.1 16.0 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC32812.1 - 3.9e-39 134.0 0.1 9e-19 68.1 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGC32812.1 - 8.5e-28 96.0 11.8 5.6e-23 80.5 0.0 3.1 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGC32812.1 - 5.2e-10 39.2 0.2 3e-09 36.8 0.1 2.3 2 0 0 2 2 2 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGC32812.1 - 1e-06 28.0 66.8 0.00021 20.4 17.5 4.0 2 2 2 4 4 4 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGC32812.1 - 1.2e-06 28.7 1.1 0.19 11.6 0.0 4.1 3 1 0 3 3 3 2 AAA domain DUF258 PF03193.11 EGC32812.1 - 7.6e-06 25.1 0.0 0.00029 20.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC32812.1 - 1.2e-05 24.7 0.2 0.0028 17.1 0.1 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC32812.1 - 0.00017 21.0 0.1 0.0012 18.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC32812.1 - 0.00025 21.1 0.0 0.093 12.8 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC32812.1 - 0.0045 16.0 3.0 0.48 9.4 0.0 3.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_33 PF13671.1 EGC32812.1 - 0.0054 16.6 0.3 1 9.2 0.2 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC32812.1 - 0.013 16.3 0.0 0.74 10.6 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC32812.1 - 0.022 14.7 0.0 0.44 10.5 0.0 2.4 2 0 0 2 2 2 0 AAA ATPase domain UPF0079 PF02367.12 EGC32812.1 - 0.026 14.1 0.5 0.63 9.6 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 FtsK_SpoIIIE PF01580.13 EGC32812.1 - 0.036 13.5 0.0 7 6.0 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_18 PF13238.1 EGC32812.1 - 0.036 14.3 0.1 0.65 10.3 0.0 2.7 2 0 0 2 2 2 0 AAA domain cobW PF02492.14 EGC32812.1 - 0.036 13.4 0.1 0.11 11.8 0.0 1.8 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SbcCD_C PF13558.1 EGC32812.1 - 0.039 13.8 0.0 0.57 10.1 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit BESS PF02944.15 EGC32812.1 - 0.074 12.6 0.0 0.3 10.6 0.1 1.9 2 0 0 2 2 2 0 BESS motif AAA_30 PF13604.1 EGC32812.1 - 0.082 12.4 0.1 3.5 7.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGC32812.1 - 0.22 11.7 0.4 5.6 7.1 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_28 PF13521.1 EGC32812.1 - 0.96 9.3 4.1 0.54 10.2 0.3 2.3 2 0 0 2 2 2 0 AAA domain LRR_4 PF12799.2 EGC32813.1 - 2.2e-13 49.4 38.4 9.2e-08 31.5 5.1 3.3 2 1 2 4 4 4 3 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EGC32813.1 - 3.6e-12 46.1 4.3 8.4e-12 44.9 3.0 1.4 1 1 0 1 1 1 1 Leucine-rich repeat LRR_8 PF13855.1 EGC32813.1 - 3.4e-08 33.0 18.2 5.5e-06 26.0 1.0 2.9 3 0 0 3 3 3 2 Leucine rich repeat LRR_6 PF13516.1 EGC32813.1 - 7.9e-06 25.4 19.0 0.013 15.4 0.9 4.8 5 0 0 5 5 5 3 Leucine Rich repeat LRR_1 PF00560.28 EGC32813.1 - 0.00028 20.4 15.3 0.23 11.6 0.1 4.1 2 2 1 3 3 3 2 Leucine Rich Repeat LRR_7 PF13504.1 EGC32813.1 - 0.0013 18.5 14.9 0.67 10.3 1.2 5.1 4 1 1 5 5 5 2 Leucine rich repeat PDZ_1 PF12812.2 EGC32813.1 - 0.16 11.8 1.6 5 7.0 0.1 3.1 3 0 0 3 3 3 0 PDZ-like domain zf-CCCH_2 PF14608.1 EGC32815.1 - 2.3e-05 24.1 4.9 0.0011 18.9 2.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type zf-CCCH PF00642.19 EGC32815.1 - 0.00027 20.5 5.3 0.014 15.0 1.9 2.5 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Sec7 PF01369.15 EGC32816.1 - 4.9e-69 231.8 1.2 7.4e-69 231.2 0.8 1.2 1 0 0 1 1 1 1 Sec7 domain PH PF00169.24 EGC32816.1 - 1e-21 77.0 0.3 1.7e-21 76.3 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC32816.1 - 1.3e-12 47.9 0.3 2.6e-12 46.9 0.2 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EGC32816.1 - 6e-05 22.8 0.1 0.00018 21.3 0.0 1.9 1 1 0 1 1 1 1 PH domain PH_6 PF15406.1 EGC32816.1 - 0.00042 20.3 0.0 0.057 13.4 0.0 2.4 1 1 1 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EGC32816.1 - 0.0021 18.0 0.0 0.021 14.8 0.0 2.3 1 1 1 2 2 2 1 Pleckstrin homology domain UbiA PF01040.13 EGC32817.1 - 1.7e-24 86.4 11.8 3.1e-24 85.5 8.2 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Pex14_N PF04695.8 EGC32817.1 - 0.94 9.5 5.5 0.21 11.6 0.9 2.0 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MOSC_N PF03476.11 EGC32818.1 - 3.8e-32 110.5 0.0 7.4e-32 109.5 0.0 1.5 1 0 0 1 1 1 1 MOSC N-terminal beta barrel domain MOSC PF03473.12 EGC32818.1 - 6.1e-17 61.3 0.0 9.3e-17 60.7 0.0 1.3 1 0 0 1 1 1 1 MOSC domain Peptidase_C11 PF03415.9 EGC32818.1 - 0.046 12.7 0.0 0.07 12.0 0.0 1.2 1 0 0 1 1 1 0 Clostripain family Arf PF00025.16 EGC32819.1 - 2e-71 238.8 0.0 2.3e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGC32819.1 - 8.8e-12 44.4 0.3 1.2e-07 30.7 0.0 2.7 2 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGC32819.1 - 5.8e-10 38.6 0.0 7.1e-10 38.3 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC32819.1 - 2e-09 37.0 0.0 2.3e-09 36.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC32819.1 - 8.8e-08 32.6 0.0 1.2e-07 32.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC32819.1 - 2e-07 30.3 0.0 2.2e-07 30.2 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC32819.1 - 2.6e-05 24.1 0.0 6.9e-05 22.7 0.0 1.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC32819.1 - 0.0033 16.9 0.0 0.043 13.2 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain DUF3818 PF12825.2 EGC32820.1 - 2.5e-21 75.7 3.3 2.6e-14 52.6 0.3 3.9 3 2 1 4 4 4 2 Domain of unknown function in PX-proteins (DUF3818) 7tm_3 PF00003.17 EGC32821.1 - 4.2e-16 59.0 36.2 4.2e-16 59.0 25.1 2.3 2 0 0 2 2 2 1 7 transmembrane sweet-taste receptor of 3 GCPR 7tm_3 PF00003.17 EGC32822.1 - 4.3e-19 68.8 32.1 4.3e-19 68.8 22.2 2.9 3 0 0 3 3 3 1 7 transmembrane sweet-taste receptor of 3 GCPR AreA_N PF07573.6 EGC32822.1 - 1.4 9.5 7.3 0.83 10.2 0.8 2.6 2 0 0 2 2 2 0 Nitrogen regulatory protein AreA N terminus Neur_chan_memb PF02932.11 EGC32822.1 - 4.2 7.1 19.4 0.11 12.3 5.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Lipase_GDSL PF00657.17 EGC32823.1 - 2.1e-14 53.8 0.0 2e-13 50.6 0.0 2.1 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase Lipase_GDSL_2 PF13472.1 EGC32823.1 - 7.5e-13 48.9 0.0 1.3e-12 48.1 0.0 1.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family FAD_binding_3 PF01494.14 EGC32824.1 - 4.7e-07 29.1 0.0 0.0029 16.7 0.0 2.4 2 1 0 2 2 2 2 FAD binding domain DUF2058 PF09831.4 EGC32824.1 - 0.064 13.1 3.9 0.053 13.3 0.8 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2058) Meth_synt_2 PF01717.13 EGC32825.1 - 9.1e-08 31.4 0.0 6.9e-05 21.9 0.0 2.3 2 1 0 2 2 2 2 Cobalamin-independent synthase, Catalytic domain MCR_D PF02505.9 EGC32825.1 - 0.022 14.3 0.0 0.24 10.9 0.0 2.2 2 0 0 2 2 2 0 Methyl-coenzyme M reductase operon protein D Abhydrolase_6 PF12697.2 EGC32826.1 - 1.3e-29 103.7 0.0 1.7e-29 103.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC32826.1 - 9.6e-16 58.0 0.0 2.6e-15 56.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC32826.1 - 1.6e-11 44.1 0.0 2.6e-11 43.4 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF676 PF05057.9 EGC32826.1 - 5.6e-06 25.8 0.0 0.065 12.5 0.0 2.3 2 0 0 2 2 2 2 Putative serine esterase (DUF676) Ndr PF03096.9 EGC32826.1 - 0.0022 16.5 0.0 0.0038 15.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family Esterase PF00756.15 EGC32826.1 - 0.0046 16.4 0.0 0.0078 15.6 0.0 1.3 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EGC32826.1 - 0.0082 15.2 0.0 0.0082 15.2 0.0 2.8 3 0 0 3 3 3 1 Alpha/beta hydrolase of unknown function (DUF915) DUF2305 PF10230.4 EGC32826.1 - 0.011 15.2 0.0 0.022 14.1 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2305) Hydrolase_4 PF12146.3 EGC32826.1 - 0.027 14.3 0.0 0.089 12.6 0.0 1.8 2 0 0 2 2 2 0 Putative lysophospholipase PGAP1 PF07819.8 EGC32826.1 - 0.046 13.3 0.0 0.14 11.6 0.0 1.9 2 0 0 2 2 2 0 PGAP1-like protein Ser_hydrolase PF06821.8 EGC32826.1 - 0.047 13.3 0.0 0.078 12.5 0.0 1.3 1 0 0 1 1 1 0 Serine hydrolase FNIP PF05725.7 EGC32827.1 - 9.1e-58 191.9 59.8 9.3e-11 41.5 0.5 8.1 5 1 4 9 9 9 8 FNIP Repeat LRR_6 PF13516.1 EGC32828.1 - 0.0033 17.3 0.3 0.07 13.2 0.1 9.6 10 1 0 10 10 10 4 Leucine Rich repeat Seipin PF06775.9 EGC32829.1 - 1.5e-52 178.0 2.3 2.6e-52 177.2 1.6 1.4 1 0 0 1 1 1 1 Putative adipose-regulatory protein (Seipin) DUF4131 PF13567.1 EGC32829.1 - 0.16 11.3 0.8 3 7.1 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) FAD_binding_3 PF01494.14 EGC32830.1 - 1.7e-46 158.9 0.0 1.2e-29 103.5 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain TrkA_N PF02254.13 EGC32830.1 - 0.025 14.5 0.0 0.091 12.7 0.0 2.0 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox_2 PF07992.9 EGC32830.1 - 0.043 13.6 0.0 0.1 12.4 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGC32830.1 - 0.045 12.8 0.0 0.1 11.6 0.0 1.6 1 0 0 1 1 1 0 Thi4 family DUF1796 PF08795.5 EGC32831.1 - 1.6 8.3 8.9 0.67 9.5 3.8 2.1 1 1 1 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) DUF745 PF05335.8 EGC32831.1 - 7.5 6.0 6.6 1.6 8.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF745) R3H-assoc PF13902.1 EGC32832.1 - 3.3e-28 98.2 1.0 7.1e-28 97.1 0.7 1.6 1 0 0 1 1 1 1 R3H-associated N-terminal domain R3H PF01424.17 EGC32832.1 - 1.4e-06 27.8 0.1 3.4e-06 26.6 0.0 1.7 2 0 0 2 2 2 1 R3H domain Thioredoxin PF00085.15 EGC32833.1 - 2.4e-21 75.3 0.0 3e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EGC32833.1 - 1.4e-07 31.1 0.0 1.6e-07 30.9 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGC32833.1 - 1.9e-05 24.6 0.0 7.3e-05 22.8 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC32833.1 - 0.00063 19.9 0.1 0.01 15.9 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGC32833.1 - 0.011 15.7 0.0 0.015 15.2 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like Redoxin PF08534.5 EGC32833.1 - 0.016 14.7 0.0 0.021 14.3 0.0 1.2 1 0 0 1 1 1 0 Redoxin AhpC-TSA PF00578.16 EGC32833.1 - 0.03 14.0 0.0 0.031 13.9 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family HD_4 PF13328.1 EGC32834.1 - 5.1e-25 87.9 0.0 6.7e-25 87.5 0.0 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGC32834.1 - 1.6e-05 24.8 0.4 2.8e-05 24.0 0.3 1.4 1 0 0 1 1 1 1 HD domain RNA_lig_T4_1 PF09511.5 EGC32834.1 - 0.032 13.7 0.1 0.042 13.3 0.1 1.3 1 0 0 1 1 1 0 RNA ligase Response_reg PF00072.19 EGC32836.1 - 6.6e-29 100.1 0.3 1.8e-21 76.2 0.1 2.4 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EGC32836.1 - 8.1e-17 60.9 4.6 3.6e-16 58.8 3.2 2.2 1 1 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase VKOR PF07884.9 EGC32836.1 - 1.4 8.7 7.6 0.65 9.8 2.0 2.4 2 0 0 2 2 2 0 Vitamin K epoxide reductase family FAT PF02259.18 EGC32838.1 - 3e-115 384.9 3.6 1.6e-114 382.5 0.1 3.1 2 1 0 2 2 2 1 FAT domain DUF3385 PF11865.3 EGC32838.1 - 1.4e-59 200.6 4.3 1.2e-54 184.6 0.1 4.3 4 1 1 5 5 4 2 Domain of unknown function (DUF3385) PI3_PI4_kinase PF00454.22 EGC32838.1 - 1.8e-58 197.8 1.4 3.2e-58 196.9 1.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase Rapamycin_bind PF08771.6 EGC32838.1 - 2.1e-40 136.8 0.7 2.1e-40 136.8 0.5 3.6 4 0 0 4 4 4 1 Rapamycin binding domain HEAT_2 PF13646.1 EGC32838.1 - 1.4e-24 86.1 7.0 0.002 18.3 0.0 9.5 5 1 3 8 8 8 6 HEAT repeats FATC PF02260.15 EGC32838.1 - 7.4e-17 60.4 0.2 2.4e-16 58.8 0.2 2.0 1 0 0 1 1 1 1 FATC domain HEAT PF02985.17 EGC32838.1 - 2.4e-16 58.2 23.5 0.035 14.1 0.0 12.4 12 0 0 12 12 11 3 HEAT repeat HEAT_EZ PF13513.1 EGC32838.1 - 5.1e-11 42.7 22.2 0.0057 17.1 0.1 11.1 9 3 4 13 13 11 3 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC32838.1 - 1.5e-06 28.4 2.9 9 6.7 0.0 7.3 6 2 1 7 7 7 1 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGC32838.1 - 2e-06 27.7 9.4 0.42 10.4 0.0 6.3 3 2 2 6 6 6 4 non-SMC mitotic condensation complex subunit 1 UME PF08064.8 EGC32838.1 - 2.2e-05 24.3 6.7 0.62 10.0 0.0 7.0 7 1 1 8 8 8 1 UME (NUC010) domain Arm PF00514.18 EGC32838.1 - 0.0038 17.0 3.9 13 5.7 0.0 6.2 6 0 0 6 6 6 0 Armadillo/beta-catenin-like repeat CLASP_N PF12348.3 EGC32838.1 - 0.032 13.5 4.0 0.58 9.4 0.0 4.4 5 2 1 6 6 6 0 CLASP N terminal TPR_7 PF13176.1 EGC32838.1 - 0.1 12.4 0.8 3.9 7.5 0.1 3.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32838.1 - 0.12 12.6 0.9 1.5 9.2 0.0 3.4 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32838.1 - 0.15 12.0 2.9 49 3.9 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat PA14 PF07691.7 EGC32839.1 - 0.013 15.1 0.0 0.033 13.8 0.0 1.6 1 0 0 1 1 1 0 PA14 domain Jun PF03957.8 EGC32839.1 - 0.1 12.2 1.9 0.15 11.7 1.3 1.1 1 0 0 1 1 1 0 Jun-like transcription factor E1-E2_ATPase PF00122.15 EGC32840.1 - 6e-46 156.3 0.1 6e-46 156.3 0.1 1.8 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGC32840.1 - 3.5e-38 132.1 0.0 5.1e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC32840.1 - 2.7e-15 57.0 0.0 7.2e-15 55.6 0.0 1.8 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGC32840.1 - 4.2e-08 33.2 0.0 1.4e-07 31.4 0.0 2.0 1 0 0 1 1 1 1 Heavy-metal-associated domain Hydrolase_3 PF08282.7 EGC32840.1 - 0.0013 18.3 10.1 0.07 12.6 0.4 3.9 4 0 0 4 4 4 2 haloacid dehalogenase-like hydrolase LRR_4 PF12799.2 EGC32842.1 - 1.1e-08 34.4 42.1 0.00011 21.7 1.6 7.6 5 3 3 8 8 8 7 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC32842.1 - 2.8e-07 29.9 51.5 0.0068 16.3 0.6 11.8 12 0 0 12 12 12 6 Leucine Rich repeat LRR_7 PF13504.1 EGC32842.1 - 0.0007 19.3 31.4 12 6.5 0.0 9.3 9 0 0 9 9 9 4 Leucine rich repeat LRR_1 PF00560.28 EGC32842.1 - 0.0042 16.9 49.8 2.6 8.4 0.7 11.0 11 2 0 11 11 11 6 Leucine Rich Repeat LRR_8 PF13855.1 EGC32842.1 - 0.013 15.2 40.5 0.063 13.0 2.3 7.1 4 2 2 6 6 6 0 Leucine rich repeat RCR PF12273.3 EGC32842.1 - 2.4 8.7 12.1 4.8 7.7 8.4 1.4 1 0 0 1 1 1 0 Chitin synthesis regulation, resistance to Congo red Metallophos PF00149.23 EGC32843.1 - 2.8e-13 49.7 3.0 2.8e-13 49.7 2.1 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Sda PF08970.5 EGC32843.1 - 0.074 12.5 0.0 0.16 11.5 0.0 1.5 1 0 0 1 1 1 0 Sporulation inhibitor A FKBP_C PF00254.23 EGC32844.1 - 1.3e-29 102.0 0.0 1.6e-29 101.7 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF845 PF05820.6 EGC32844.1 - 0.02 14.6 0.0 0.026 14.2 0.0 1.1 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF845) RasGAP PF00616.14 EGC32845.1 - 3.8e-43 147.4 4.7 9.5e-43 146.1 3.3 1.7 1 0 0 1 1 1 1 GTPase-activator protein for Ras-like GTPase C2 PF00168.25 EGC32845.1 - 1.3e-14 53.8 0.0 3.1e-14 52.5 0.0 1.7 1 0 0 1 1 1 1 C2 domain Pex14_N PF04695.8 EGC32847.1 - 1.5e-35 122.1 2.6 1.5e-35 122.1 1.8 6.7 3 2 2 5 5 5 1 Peroxisomal membrane anchor protein (Pex14p) conserved region ECH PF00378.15 EGC32852.1 - 2.1e-50 171.1 0.2 2.8e-50 170.7 0.1 1.2 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family BRE1 PF08647.6 EGC32852.1 - 0.089 12.7 0.4 0.19 11.7 0.3 1.5 1 0 0 1 1 1 0 BRE1 E3 ubiquitin ligase Rad51 PF08423.6 EGC32854.1 - 2.7e-36 124.7 0.0 1.3e-35 122.5 0.0 1.8 1 1 0 1 1 1 1 Rad51 AAA_25 PF13481.1 EGC32854.1 - 1.3e-11 44.3 0.0 1.7e-11 43.8 0.0 1.1 1 0 0 1 1 1 1 AAA domain KaiC PF06745.8 EGC32854.1 - 3.3e-08 32.9 0.0 4.9e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 KaiC DnaB_C PF03796.10 EGC32854.1 - 0.00061 18.7 1.0 0.57 9.0 0.1 2.8 2 1 1 3 3 3 2 DnaB-like helicase C terminal domain RecA PF00154.16 EGC32854.1 - 0.0082 15.2 0.3 1 8.3 0.1 2.1 2 0 0 2 2 2 2 recA bacterial DNA recombination protein PPV_E1_C PF00519.12 EGC32854.1 - 0.047 12.3 0.4 0.1 11.2 0.0 1.6 2 0 0 2 2 2 0 Papillomavirus helicase AAA_18 PF13238.1 EGC32854.1 - 0.058 13.7 0.0 0.18 12.1 0.0 1.8 1 1 0 1 1 1 0 AAA domain BLOC1_2 PF10046.4 EGC32854.1 - 0.091 12.9 0.2 4.2 7.5 0.1 2.3 2 0 0 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 AAA PF00004.24 EGC32854.1 - 0.12 12.5 0.0 1.2 9.2 0.0 2.3 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) PUF PF00806.14 EGC32854.1 - 0.18 11.3 1.8 1.2 8.7 0.5 2.8 2 1 0 2 2 2 0 Pumilio-family RNA binding repeat RhoGEF PF00621.15 EGC32855.1 - 2.9e-40 138.0 1.8 2.9e-40 138.0 1.2 3.6 4 1 0 4 4 4 1 RhoGEF domain zf-ribbon_3 PF13248.1 EGC32855.1 - 0.00015 20.8 4.2 0.00015 20.8 2.9 1.8 2 0 0 2 2 2 1 zinc-ribbon domain DZR PF12773.2 EGC32855.1 - 0.00048 19.8 0.5 0.0013 18.4 0.4 1.7 1 0 0 1 1 1 1 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGC32855.1 - 0.002 17.5 5.3 0.0045 16.4 3.7 1.6 1 0 0 1 1 1 1 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EGC32855.1 - 0.085 12.6 2.2 0.44 10.4 1.6 2.3 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like DUF4588 PF15251.1 EGC32856.1 - 1.5e-05 25.0 8.2 1.5e-05 25.0 5.7 1.8 1 1 0 2 2 2 1 Domain of unknown function (DUF4588) DUF3807 PF12720.2 EGC32856.1 - 9.7 6.3 14.1 0.14 12.3 4.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3807) Peptidase_C1 PF00112.18 EGC32857.1 - 1e-85 287.1 4.1 1.4e-85 286.6 2.8 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC32857.1 - 4.5e-15 55.6 2.5 9.3e-15 54.6 1.7 1.6 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC32857.1 - 0.0068 14.9 2.7 0.15 10.5 0.0 2.4 2 1 0 2 2 2 2 Peptidase C1-like family Inhibitor_I24 PF10465.4 EGC32857.1 - 0.13 11.9 0.4 1.3 8.7 0.3 2.1 1 1 0 1 1 1 0 PinA peptidase inhibitor Peptidase_C1 PF00112.18 EGC32858.1 - 5.9e-81 271.5 5.5 5.9e-81 271.5 3.8 1.3 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC32858.1 - 1.8e-15 56.9 7.9 3.3e-15 56.0 5.5 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC32858.1 - 0.32 9.4 5.1 0.98 7.8 0.1 2.6 3 0 0 3 3 3 0 Peptidase C1-like family Peptidase_C1 PF00112.18 EGC32859.1 - 2.9e-84 282.3 7.0 5.1e-84 281.5 4.9 1.4 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC32859.1 - 5.5e-16 58.5 8.6 1.1e-15 57.6 5.9 1.5 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC32859.1 - 0.0071 14.9 3.4 0.075 11.5 0.1 2.3 2 1 0 2 2 2 2 Peptidase C1-like family RTX PF02382.10 EGC32859.1 - 0.028 12.7 1.0 0.039 12.2 0.7 1.1 1 0 0 1 1 1 0 RTX N-terminal domain zf-C2H2_2 PF12756.2 EGC32860.1 - 8.7e-39 131.7 27.6 2.7e-18 65.9 2.3 3.4 3 0 0 3 3 3 3 C2H2 type zinc-finger (2 copies) zf-C2H2_jaz PF12171.3 EGC32860.1 - 1.1e-05 25.4 3.0 1.1e-05 25.4 2.1 4.7 5 0 0 5 5 5 1 Zinc-finger double-stranded RNA-binding zf-C2H2 PF00096.21 EGC32860.1 - 0.0085 16.3 1.5 0.0085 16.3 1.0 5.4 5 1 0 5 5 5 1 Zinc finger, C2H2 type zf-BED PF02892.10 EGC32860.1 - 0.023 14.4 19.2 0.11 12.2 0.3 5.4 5 0 0 5 5 5 0 BED zinc finger zf-C2H2_4 PF13894.1 EGC32860.1 - 0.24 11.7 0.2 0.24 11.7 0.2 5.4 5 0 0 5 5 5 0 C2H2-type zinc finger PyrI_C PF02748.10 EGC32860.1 - 0.35 10.3 0.1 0.35 10.3 0.1 4.2 5 0 0 5 5 5 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain Transpos_assoc PF13963.1 EGC32860.1 - 0.45 10.5 9.4 0.95 9.4 0.4 3.5 3 0 0 3 3 3 0 Transposase-associated domain LMBR1 PF04791.11 EGC32861.1 - 5e-40 137.4 31.9 1.2e-39 136.2 22.1 1.5 1 1 0 1 1 1 1 LMBR1-like membrane protein DUF2852 PF11014.3 EGC32861.1 - 0.21 11.5 2.6 2.2 8.2 0.0 3.2 3 1 0 3 3 3 0 Protein of unknown function (DUF2852) Acyl_transf_1 PF00698.16 EGC32862.1 - 4.7e-18 65.5 0.0 5.7e-18 65.3 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain PLDc PF00614.17 EGC32863.1 - 9.4e-09 34.7 0.1 0.0058 16.3 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGC32863.1 - 3.4e-07 30.0 1.1 0.00087 19.0 0.0 3.1 2 1 0 2 2 2 2 PLD-like domain Neur_chan_memb PF02932.11 EGC32863.1 - 0.55 10.0 3.9 0.87 9.4 2.7 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Pex14_N PF04695.8 EGC32863.1 - 4.6 7.2 14.5 7.3 6.6 1.9 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ctr PF04145.10 EGC32863.1 - 6.2 6.8 6.8 9.7 6.2 0.6 2.4 2 0 0 2 2 2 0 Ctr copper transporter family PLDc PF00614.17 EGC32864.1 - 3e-08 33.2 0.1 0.011 15.5 0.1 2.6 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGC32864.1 - 4.5e-05 23.2 0.9 0.0018 17.9 0.0 2.8 2 0 0 2 2 2 1 PLD-like domain Menin PF05053.8 EGC32864.1 - 3.6 5.6 14.6 2.1 6.4 3.2 2.4 2 0 0 2 2 2 0 Menin Ctr PF04145.10 EGC32864.1 - 6.3 6.8 13.3 14 5.7 0.2 3.7 3 0 0 3 3 3 0 Ctr copper transporter family AAA_16 PF13191.1 EGC32865.1 - 4.9e-28 98.3 0.0 1.3e-27 97.0 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Response_reg PF00072.19 EGC32865.1 - 1.4e-25 89.4 0.3 1.8e-24 85.9 0.1 2.6 2 0 0 2 2 2 1 Response regulator receiver domain HATPase_c PF02518.21 EGC32865.1 - 1.1e-24 86.2 0.3 2.6e-24 85.0 0.2 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Pkinase PF00069.20 EGC32865.1 - 7.2e-21 74.5 0.0 1.1e-09 37.8 0.0 2.9 2 0 0 2 2 2 2 Protein kinase domain HisKA PF00512.20 EGC32865.1 - 1.9e-15 56.6 0.1 4.3e-15 55.4 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain Pkinase_Tyr PF07714.12 EGC32865.1 - 1.7e-12 47.0 0.0 9.3e-07 28.1 0.0 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase GAF_3 PF13492.1 EGC32865.1 - 3.2e-07 30.5 0.0 2.8e-06 27.4 0.0 2.4 1 1 0 1 1 1 1 GAF domain GAF PF01590.21 EGC32865.1 - 1.7e-06 28.2 0.0 4.7e-06 26.8 0.0 1.8 1 1 0 1 1 1 1 GAF domain GAF_2 PF13185.1 EGC32865.1 - 4.6e-05 23.9 0.0 0.00017 22.0 0.0 2.0 1 0 0 1 1 1 1 GAF domain TPR_12 PF13424.1 EGC32865.1 - 0.033 14.1 9.4 0.028 14.3 3.9 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32865.1 - 1.4 9.0 11.9 0.027 14.3 0.3 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat Ribonuc_red_lgC PF02867.10 EGC32866.1 - 1.3e-211 703.8 0.0 1.7e-211 703.5 0.0 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, barrel domain Ribonuc_red_lgN PF00317.16 EGC32866.1 - 7.4e-21 73.7 0.0 2e-20 72.3 0.0 1.8 1 0 0 1 1 1 1 Ribonucleotide reductase, all-alpha domain ATP-cone PF03477.11 EGC32866.1 - 2e-16 60.1 0.1 1.6e-15 57.3 0.0 2.3 2 0 0 2 2 2 1 ATP cone domain NRDD PF13597.1 EGC32866.1 - 0.014 13.5 0.0 0.021 12.9 0.0 1.2 1 0 0 1 1 1 0 Anaerobic ribonucleoside-triphosphate reductase NAPRTase PF04095.11 EGC32866.1 - 0.045 13.0 0.0 0.085 12.1 0.0 1.4 1 0 0 1 1 1 0 Nicotinate phosphoribosyltransferase (NAPRTase) family DUF382 PF04037.8 EGC32867.1 - 4.9e-55 184.8 0.2 4.9e-55 184.8 0.1 3.8 5 0 0 5 5 5 1 Domain of unknown function (DUF382) PSP PF04046.11 EGC32867.1 - 1.5e-22 78.6 5.2 2.8e-22 77.8 3.6 1.5 1 0 0 1 1 1 1 PSP SR-25 PF10500.4 EGC32867.1 - 0.0097 15.4 12.3 0.0097 15.4 8.5 4.4 5 0 0 5 5 5 2 Nuclear RNA-splicing-associated protein DUF1212 PF06738.7 EGC32868.1 - 1.6e-43 148.4 14.4 4.9e-40 137.0 1.3 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF1212) DUF3815 PF12821.2 EGC32868.1 - 5.8e-19 68.3 37.8 1e-17 64.2 7.9 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3815) zf-C3H1 PF10650.4 EGC32869.1 - 8.6e-11 41.1 2.7 1.6e-10 40.2 1.8 1.5 1 0 0 1 1 1 1 Putative zinc-finger domain DSX_dimer PF08828.5 EGC32870.1 - 0.097 12.2 0.4 0.78 9.3 0.0 2.5 2 0 0 2 2 2 0 Doublesex dimerisation domain TP_methylase PF00590.15 EGC32872.1 - 9.6e-17 61.3 0.0 2e-16 60.3 0.0 1.5 1 1 0 1 1 1 1 Tetrapyrrole (Corrin/Porphyrin) Methylases Glyco_hydro_63 PF03200.11 EGC32873.1 - 1.1e-09 36.8 15.1 5.8e-08 31.0 2.9 4.3 3 1 0 3 3 3 3 Mannosyl oligosaccharide glucosidase CS PF04969.11 EGC32874.1 - 2.5e-06 27.9 0.0 3.2e-06 27.6 0.0 1.2 1 0 0 1 1 1 1 CS domain Cytotoxic PF09000.5 EGC32874.1 - 0.047 13.7 0.1 0.062 13.3 0.1 1.1 1 0 0 1 1 1 0 Cytotoxic Vps51 PF08700.6 EGC32875.1 - 2.1e-06 27.4 0.1 9.2e-06 25.4 0.0 2.2 1 0 0 1 1 1 1 Vps51/Vps67 Sec5 PF15469.1 EGC32875.1 - 6.5e-06 25.9 4.1 6.8e-06 25.9 1.3 2.2 2 0 0 2 2 2 1 Exocyst complex component Sec5 RNA_pol_A_bac PF01000.21 EGC32876.1 - 4e-36 123.5 0.3 1.1e-35 122.1 0.1 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb3/RpoA insert domain RNA_pol_L PF01193.19 EGC32876.1 - 1.2e-20 72.3 0.0 1.5e-20 72.0 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L_2 PF13656.1 EGC32876.1 - 0.017 14.5 0.3 2.5 7.6 0.1 2.4 2 0 0 2 2 2 0 RNA polymerase Rpb3/Rpb11 dimerisation domain GATase PF00117.23 EGC32877.1 - 2e-11 43.7 0.5 1.5e-10 40.8 0.4 1.9 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGC32877.1 - 0.00087 18.9 0.0 0.0015 18.1 0.0 1.4 1 0 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EGC32877.1 - 0.0012 18.2 0.6 0.0028 17.1 0.4 1.6 1 1 0 1 1 1 1 Peptidase C26 Ank_2 PF12796.2 EGC32878.1 - 2.1e-23 82.4 1.3 4.9e-10 39.6 0.8 3.7 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC32878.1 - 2.2e-17 61.8 0.0 0.0013 18.4 0.1 5.7 5 0 0 5 5 5 3 Ankyrin repeat Ank_4 PF13637.1 EGC32878.1 - 9e-15 54.7 5.1 6e-05 23.4 0.1 4.8 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32878.1 - 2.3e-13 48.9 4.3 0.01 15.9 0.1 6.1 6 0 0 6 6 6 3 Ankyrin repeat Ank_5 PF13857.1 EGC32878.1 - 7.8e-10 38.6 2.9 2.8e-05 24.2 0.0 5.8 4 2 2 6 6 6 4 Ankyrin repeats (many copies) zf-C3HC4_3 PF13920.1 EGC32878.1 - 4.2e-05 23.1 12.6 4.2e-05 23.1 8.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) DUF3439 PF11921.3 EGC32878.1 - 8.1e-05 22.3 6.2 0.00025 20.7 4.3 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC32878.1 - 0.0082 15.9 13.4 0.0082 15.9 9.3 1.6 2 0 0 2 2 2 1 Mucin-like glycoprotein Acetyltransf_7 PF13508.1 EGC32879.1 - 1.1e-12 47.9 0.0 1.7e-12 47.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC32879.1 - 1.7e-10 40.7 0.0 2.2e-10 40.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC32879.1 - 6.1e-09 35.7 0.0 9.2e-09 35.2 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC32879.1 - 0.0008 19.5 0.0 0.001 19.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC32879.1 - 0.022 14.6 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase MOZ_SAS PF01853.13 EGC32879.1 - 0.04 13.1 0.0 0.049 12.8 0.0 1.3 1 0 0 1 1 1 0 MOZ/SAS family FR47 PF08445.5 EGC32879.1 - 0.064 13.0 0.0 0.11 12.2 0.0 1.3 1 0 0 1 1 1 0 FR47-like protein Cpn60_TCP1 PF00118.19 EGC32880.1 - 3.6e-139 464.5 11.1 4.1e-139 464.3 7.7 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF956 PF06115.6 EGC32880.1 - 0.00075 19.0 0.3 0.067 12.7 0.0 2.7 2 0 0 2 2 2 2 Domain of unknown function (DUF956) SNAPc19 PF15497.1 EGC32881.1 - 2.1 8.6 8.1 1.1 9.5 1.9 2.3 2 0 0 2 2 2 0 snRNA-activating protein complex subunit 19, SNAPc subunit 19 Vps55 PF04133.9 EGC32882.1 - 7.7e-38 128.9 4.2 8.7e-38 128.7 2.9 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting 55 YqzM PF14141.1 EGC32882.1 - 0.53 10.1 10.2 0.36 10.6 0.2 3.0 3 0 0 3 3 3 0 YqzM-like protein WD40 PF00400.27 EGC32883.1 - 6.9e-58 190.6 36.3 1.3e-09 37.5 0.4 8.8 8 0 0 8 8 8 8 WD domain, G-beta repeat DENN PF02141.16 EGC32883.1 - 2.9e-52 177.0 5.0 8.2e-52 175.6 3.5 1.9 1 0 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGC32883.1 - 1.4e-17 63.4 0.6 4e-17 61.9 0.4 1.9 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGC32883.1 - 2.2e-15 56.4 3.4 5.9e-15 55.0 2.4 1.8 1 0 0 1 1 1 1 dDENN domain C2 PF00168.25 EGC32883.1 - 2.1e-10 40.3 0.6 8.3e-10 38.3 0.4 2.1 1 0 0 1 1 1 1 C2 domain SBF2 PF12335.3 EGC32883.1 - 1.2e-08 34.5 0.6 1.2e-08 34.5 0.4 3.2 3 0 0 3 3 3 1 Myotubularin protein CAF-1_p150 PF11600.3 EGC32883.1 - 0.00078 18.8 28.6 0.00078 18.8 19.8 4.3 4 1 0 4 4 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF3591 PF12157.3 EGC32884.1 - 1.1e-114 383.3 0.0 1.1e-114 383.3 0.0 4.1 4 0 0 4 4 4 1 Protein of unknown function (DUF3591) Bromodomain PF00439.20 EGC32884.1 - 5.5e-17 61.4 1.0 3.1e-16 59.0 0.7 2.3 1 0 0 1 1 1 1 Bromodomain TBP-binding PF09247.6 EGC32884.1 - 6.9e-06 26.1 0.9 2.4e-05 24.4 0.6 1.9 1 0 0 1 1 1 1 TATA box-binding protein binding GATA PF00320.22 EGC32886.1 - 6.4e-07 28.6 1.2 6.4e-07 28.6 0.9 2.1 2 1 0 2 2 2 1 GATA zinc finger MSP1_C PF07462.6 EGC32886.1 - 0.0074 14.7 5.3 0.011 14.1 3.7 1.2 1 0 0 1 1 1 1 Merozoite surface protein 1 (MSP1) C-terminus Dicty_REP PF05086.7 EGC32886.1 - 0.4 8.3 10.8 0.55 7.9 7.5 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein DUF4530 PF15039.1 EGC32886.1 - 0.64 9.9 5.3 1.2 9.0 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4530) Tir_receptor_C PF07489.6 EGC32886.1 - 0.72 9.5 8.1 0.94 9.1 5.6 1.2 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Pex14_N PF04695.8 EGC32886.1 - 6 6.9 7.3 12 5.9 5.0 1.5 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Mucin PF01456.12 EGC32886.1 - 8.8 6.1 25.8 13 5.5 17.9 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein ALMT PF11744.3 EGC32887.1 - 3.8e-15 55.4 10.9 3.8e-15 55.4 7.6 2.6 3 0 0 3 3 3 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EGC32887.1 - 1.2e-11 44.6 15.9 1.2e-11 44.6 11.0 2.7 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGC32887.1 - 0.0075 14.7 9.1 0.014 13.8 6.3 1.3 1 0 0 1 1 1 1 Fusaric acid resistance protein family Peptidase_C1 PF00112.18 EGC32888.1 - 3.5e-59 200.3 7.4 4.2e-59 200.0 5.1 1.0 1 0 0 1 1 1 1 Papain family cysteine protease PAN_3 PF08277.7 EGC32888.1 - 0.087 12.4 4.0 0.057 13.0 1.2 1.9 2 0 0 2 2 2 0 PAN-like domain Peptidase_C1_2 PF03051.10 EGC32888.1 - 0.13 10.7 2.6 7.5 4.9 0.0 2.7 3 0 0 3 3 3 0 Peptidase C1-like family MtN3_slv PF03083.11 EGC32889.1 - 1.4e-29 101.8 15.1 1.4e-15 56.9 3.3 2.3 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange MPC PF03650.8 EGC32889.1 - 0.31 10.9 1.8 17 5.3 0.1 2.6 1 1 2 3 3 3 0 Uncharacterised protein family (UPF0041) PseudoU_synth_2 PF00849.17 EGC32890.1 - 9.2e-28 97.1 8.9 8.5e-14 51.7 0.0 3.8 2 2 1 3 3 3 2 RNA pseudouridylate synthase DUF1510 PF07423.6 EGC32890.1 - 2.9 7.1 32.0 3.7 6.8 5.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Pkinase_Tyr PF07714.12 EGC32892.1 - 1.9e-59 200.8 0.0 3e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC32892.1 - 1.8e-50 171.5 0.0 3.1e-50 170.7 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain WD40 PF00400.27 EGC32892.1 - 0.0012 18.6 1.9 0.45 10.4 0.0 3.8 3 0 0 3 3 3 2 WD domain, G-beta repeat ketoacyl-synt PF00109.21 EGC32893.1 - 8.6e-63 212.1 0.0 2.7e-62 210.5 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32893.1 - 6.5e-43 147.2 0.0 1e-42 146.6 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC32893.1 - 4.1e-34 116.9 0.0 2.8e-33 114.2 0.0 2.2 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC32893.1 - 6.2e-23 81.3 0.0 1.4e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC32893.1 - 3.6e-20 72.2 3.9 5e-20 71.8 0.0 3.5 3 0 0 3 3 2 1 Methyltransferase domain adh_short PF00106.20 EGC32893.1 - 1.9e-15 57.1 0.0 4.4e-15 56.0 0.0 1.6 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGC32893.1 - 5.2e-08 32.3 0.0 0.00064 18.9 0.0 2.1 2 0 0 2 2 2 2 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC32893.1 - 6e-07 30.4 0.0 1.7e-06 28.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC32893.1 - 1.1e-06 28.3 0.1 2.5e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC32893.1 - 2.1e-06 28.1 0.0 2.6e-05 24.6 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC32893.1 - 2.9e-06 27.0 0.0 8e-06 25.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC32893.1 - 2.1e-05 24.1 7.8 0.00014 21.4 0.0 5.0 4 0 0 4 4 4 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32893.1 - 2.3e-05 23.5 0.0 4.9e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGC32893.1 - 7.7e-05 22.8 0.1 0.00021 21.4 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EGC32893.1 - 0.00012 22.6 0.0 0.00064 20.2 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Mito_carr PF00153.22 EGC32894.1 - 1.3e-62 207.4 2.4 1.9e-20 72.3 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Tim17 PF02466.14 EGC32894.1 - 0.017 15.1 0.3 0.2 11.6 0.2 2.5 2 1 0 2 2 2 0 Tim17/Tim22/Tim23/Pmp24 family Ank_2 PF12796.2 EGC32895.1 - 5.3e-32 110.0 8.2 6.4e-13 48.8 0.1 6.7 5 1 1 6 6 6 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGC32895.1 - 2.4e-22 77.5 10.9 1.5e-06 27.7 0.0 8.4 8 1 0 8 8 8 3 Ankyrin repeat Ank_4 PF13637.1 EGC32895.1 - 1.6e-21 76.2 11.2 5.4e-07 29.9 0.0 7.6 5 1 1 6 6 6 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC32895.1 - 8.7e-17 60.7 23.4 2.2e-07 30.9 0.0 8.6 6 2 3 9 9 9 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC32895.1 - 1.3e-16 59.0 9.0 8.9e-05 22.3 0.0 9.1 9 0 0 9 9 9 4 Ankyrin repeat F-box-like PF12937.2 EGC32895.1 - 2.8e-09 36.5 0.2 6.8e-09 35.3 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC32895.1 - 6.1e-08 32.1 3.7 1.2e-07 31.1 1.3 2.6 2 0 0 2 2 2 1 F-box domain PH PF00169.24 EGC32896.1 - 3.9e-08 33.4 0.0 8.3e-08 32.3 0.0 1.5 1 0 0 1 1 1 1 PH domain Sec63 PF02889.11 EGC32897.1 - 7.2e-39 133.8 4.2 1.6e-31 109.7 2.0 2.4 2 0 0 2 2 2 2 Sec63 Brl domain DnaJ PF00226.26 EGC32897.1 - 1.2e-19 69.8 0.5 5.2e-19 67.7 0.4 2.2 1 0 0 1 1 1 1 DnaJ domain CDC45 PF02724.9 EGC32897.1 - 4.4 5.2 13.9 9.6 4.1 9.6 1.5 1 0 0 1 1 1 0 CDC45-like protein S10_plectin PF03501.10 EGC32898.1 - 1.2e-38 130.8 0.4 1.5e-38 130.5 0.3 1.1 1 0 0 1 1 1 1 Plectin/S10 domain Kunitz_BPTI PF00014.18 EGC32899.1 - 0.17 12.1 2.5 1 9.5 0.0 2.8 3 0 0 3 3 3 0 Kunitz/Bovine pancreatic trypsin inhibitor domain Ctr PF04145.10 EGC32900.1 - 4.8e-25 88.2 12.7 2.7e-24 85.8 8.8 1.8 1 1 0 1 1 1 1 Ctr copper transporter family SecD_SecF PF02355.11 EGC32900.1 - 0.0031 16.7 0.2 0.0052 16.0 0.2 1.3 1 0 0 1 1 1 1 Protein export membrane protein Halogen_Hydrol PF10112.4 EGC32900.1 - 0.36 10.2 3.2 2.1 7.6 2.2 1.8 2 0 0 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein PDR_CDR PF06422.7 EGC32900.1 - 0.47 10.1 3.2 0.44 10.2 1.3 1.6 1 1 0 1 1 1 0 CDR ABC transporter DUF3586 PF12131.3 EGC32901.1 - 2.7 8.0 6.5 2 8.4 0.6 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3586) CBFD_NFYB_HMF PF00808.18 EGC32902.1 - 4.2e-20 71.5 0.0 4.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC32902.1 - 5.3e-09 36.0 0.0 6e-09 35.9 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Mpv17_PMP22 PF04117.7 EGC32903.1 - 1.5e-18 66.2 0.4 2.7e-18 65.3 0.3 1.4 1 0 0 1 1 1 1 Mpv17 / PMP22 family TPR_11 PF13414.1 EGC32904.1 - 2.6e-07 30.1 0.7 0.001 18.7 0.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_14 PF13428.1 EGC32904.1 - 2e-06 27.9 0.0 0.041 14.5 0.0 3.3 2 1 2 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC32904.1 - 0.00018 21.1 0.1 4.6 7.4 0.0 4.2 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32904.1 - 0.00079 19.0 2.7 10 6.1 0.1 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32904.1 - 0.00081 19.6 0.7 0.91 10.1 0.0 4.2 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32904.1 - 0.00099 18.6 0.2 0.31 10.7 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32904.1 - 0.015 15.5 0.2 1.6 9.1 0.0 3.1 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32904.1 - 0.02 15.0 0.7 0.48 10.7 0.1 2.9 3 0 0 3 3 3 0 Tetratricopeptide repeat TRAPPC-Trs85 PF12739.2 EGC32904.1 - 0.028 13.1 0.0 0.041 12.5 0.0 1.5 1 1 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit TPR_16 PF13432.1 EGC32904.1 - 0.03 15.0 0.0 0.54 10.9 0.0 2.5 2 1 0 2 2 2 0 Tetratricopeptide repeat PHD PF00628.24 EGC32905.1 - 1.9e-19 69.0 24.1 4.4e-11 42.2 7.3 2.7 2 0 0 2 2 2 2 PHD-finger Prok-RING_1 PF14446.1 EGC32905.1 - 9.9e-08 31.5 12.2 2.4e-06 27.1 1.5 2.6 2 0 0 2 2 2 2 Prokaryotic RING finger family 1 zf-HC5HC2H PF13771.1 EGC32905.1 - 8e-07 29.1 15.4 8.7e-06 25.8 0.8 3.4 3 0 0 3 3 3 2 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EGC32905.1 - 2e-05 24.5 13.2 6.8e-05 22.8 0.8 3.2 2 1 0 2 2 2 2 PHD-zinc-finger like domain PHD_2 PF13831.1 EGC32905.1 - 0.0013 17.9 19.2 0.0036 16.5 0.6 2.8 3 0 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EGC32905.1 - 0.0067 16.1 1.6 0.0067 16.1 1.1 2.9 3 0 0 3 3 3 2 Phorbol esters/diacylglycerol binding domain (C1 domain) Prim_Zn_Ribbon PF08273.7 EGC32905.1 - 1.8 8.6 8.6 3.3 7.8 0.1 3.2 3 0 0 3 3 3 0 Zinc-binding domain of primase-helicase zf-RING_2 PF13639.1 EGC32905.1 - 7.6 6.4 18.1 0.31 10.9 2.0 2.5 2 0 0 2 2 2 0 Ring finger domain zf-TRAF PF02176.13 EGC32907.1 - 9.5e-12 45.1 37.1 1.4e-05 25.3 5.0 4.5 2 1 3 5 5 5 4 TRAF-type zinc finger MATH PF00917.21 EGC32907.1 - 9e-11 42.0 4.1 9e-11 42.0 2.9 1.9 2 0 0 2 2 2 1 MATH domain zf-C3HC4_3 PF13920.1 EGC32907.1 - 2.1e-05 24.0 5.0 2.1e-05 24.0 3.5 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC32907.1 - 0.0044 17.0 7.8 0.0044 17.0 5.4 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Yippee-Mis18 PF03226.9 EGC32907.1 - 7 6.7 20.8 1.8 8.6 0.5 3.5 2 1 1 3 3 3 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly LRR_8 PF13855.1 EGC32908.1 - 0.00012 21.7 33.4 0.11 12.2 0.1 6.7 2 2 5 7 7 7 5 Leucine rich repeat F-box-like PF12937.2 EGC32908.1 - 0.024 14.3 2.7 0.43 10.3 0.0 3.4 4 0 0 4 4 4 0 F-box-like Glyco_hydro_47 PF01532.15 EGC32908.1 - 0.038 12.6 0.1 0.055 12.1 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 47 LRR_4 PF12799.2 EGC32908.1 - 0.092 12.4 35.6 1.4 8.6 0.7 7.6 2 1 3 5 5 5 0 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGC32908.1 - 7.6 7.2 15.0 66 4.3 0.0 7.5 8 2 1 9 9 9 0 Leucine rich repeat Fer4 PF00037.22 EGC32909.1 - 1.9e-14 52.5 16.9 1.3e-08 34.0 3.1 2.3 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_7 PF12838.2 EGC32909.1 - 2.1e-12 47.2 10.8 3.6e-12 46.4 7.5 1.4 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_16 PF13484.1 EGC32909.1 - 1.4e-10 41.7 6.0 8.2e-05 23.2 0.1 2.5 2 0 0 2 2 2 2 4Fe-4S double cluster binding domain Fer4_21 PF14697.1 EGC32909.1 - 2e-10 40.3 3.7 4.3e-05 23.2 0.2 2.2 2 0 0 2 2 2 2 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGC32909.1 - 7.5e-10 38.9 10.0 1.5e-09 37.9 6.9 1.6 1 0 0 1 1 1 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGC32909.1 - 1.2e-09 37.8 23.0 6.1e-08 32.3 9.0 1.9 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_2 PF12797.2 EGC32909.1 - 9.8e-09 34.6 14.6 7.3e-05 22.4 1.8 2.6 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_8 PF13183.1 EGC32909.1 - 5.2e-08 32.8 20.1 1.8e-05 24.6 8.4 2.1 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGC32909.1 - 1.7e-07 30.8 20.2 0.00057 19.6 3.4 2.6 3 0 0 3 3 3 2 4Fe-4S binding domain Fer4_4 PF12800.2 EGC32909.1 - 1e-06 28.5 11.7 0.0005 20.1 2.1 2.4 2 0 0 2 2 2 2 4Fe-4S binding domain Fer4_17 PF13534.1 EGC32909.1 - 2.8e-05 24.3 10.7 0.00062 20.0 8.0 2.2 1 1 2 3 3 3 3 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGC32909.1 - 5e-05 23.6 11.1 0.022 15.1 1.0 2.3 1 1 1 2 2 2 2 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGC32909.1 - 0.0014 18.9 14.9 0.15 12.4 1.8 2.5 2 0 0 2 2 2 2 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGC32909.1 - 0.0088 16.5 13.5 0.37 11.3 1.5 2.9 2 1 0 2 2 2 2 4Fe-4S single cluster domain Fer4_3 PF12798.2 EGC32909.1 - 0.025 15.1 18.1 0.062 13.8 3.2 2.3 2 0 0 2 2 2 0 4Fe-4S binding domain c-SKI_SMAD_bind PF08782.5 EGC32909.1 - 0.65 10.1 5.5 0.96 9.6 0.1 2.3 1 1 1 2 2 2 0 c-SKI Smad4 binding domain G-alpha PF00503.15 EGC32910.1 - 1.7e-65 221.2 13.7 2.2e-65 220.8 9.5 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC32910.1 - 0.0007 18.8 0.6 0.077 12.2 0.0 2.3 2 0 0 2 2 2 2 ADP-ribosylation factor family Sulfate_transp PF00916.15 EGC32911.1 - 2.9e-63 213.4 9.1 3.5e-37 127.9 0.6 2.4 1 1 1 2 2 2 2 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGC32911.1 - 8.1e-35 118.3 2.9 8.1e-35 118.3 2.0 2.3 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGC32911.1 - 1.4e-23 82.5 0.0 3e-23 81.4 0.0 1.6 1 0 0 1 1 1 1 STAS domain STAS_2 PF13466.1 EGC32911.1 - 0.005 16.8 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 STAS domain cNMP_binding PF00027.24 EGC32912.1 - 5.3e-39 131.9 0.1 3e-20 71.8 0.0 2.8 3 0 0 3 3 3 2 Cyclic nucleotide-binding domain Lactamase_B PF00753.22 EGC32912.1 - 2.2e-10 40.4 0.1 3.9e-10 39.7 0.1 1.3 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC32912.1 - 2.3e-10 40.3 0.7 6.4e-10 38.9 0.5 1.8 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Apis_Csd PF11671.3 EGC32912.1 - 0.0025 17.6 6.0 0.0073 16.1 4.2 1.8 1 0 0 1 1 1 1 Complementary sex determiner protein MoeZ_MoeB PF05237.8 EGC32912.1 - 0.1 12.1 0.0 0.53 9.9 0.0 2.1 2 0 0 2 2 2 0 MoeZ/MoeB domain WD40 PF00400.27 EGC32913.1 - 1.5e-11 43.6 1.9 1.6 8.7 0.0 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat KTSC PF13619.1 EGC32913.1 - 0.02 14.4 0.6 0.75 9.4 0.1 2.7 2 0 0 2 2 2 0 KTSC domain PD40 PF07676.7 EGC32913.1 - 0.064 12.9 0.1 2.1 8.0 0.0 2.7 2 0 0 2 2 2 0 WD40-like Beta Propeller Repeat IKI3 PF04762.7 EGC32913.1 - 0.13 10.0 0.7 0.53 8.0 0.3 2.1 2 1 0 3 3 3 0 IKI3 family MIS13 PF08202.6 EGC32913.1 - 0.18 10.8 1.7 0.26 10.2 1.2 1.2 1 0 0 1 1 1 0 Mis12-Mtw1 protein family Erf4 PF10256.4 EGC32914.1 - 1.4e-07 31.3 0.6 1.8e-06 27.8 0.4 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.4 EGC32914.1 - 0.045 12.3 1.8 0.062 11.8 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Lactamase_B_2 PF12706.2 EGC32915.1 - 2.7e-29 102.0 0.3 7.4e-27 94.1 0.4 3.4 2 1 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGC32915.1 - 0.0098 15.5 0.2 0.053 13.1 0.0 2.2 2 1 0 2 2 2 1 Metallo-beta-lactamase superfamily DCD PF06559.6 EGC32915.1 - 0.2 10.0 0.0 0.31 9.3 0.0 1.2 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) Atrophin-1 PF03154.10 EGC32915.1 - 9.7 4.1 13.2 14 3.6 9.2 1.1 1 0 0 1 1 1 0 Atrophin-1 family tRNA-synt_1e PF01406.14 EGC32916.1 - 3.8e-101 338.1 3.2 7.3e-101 337.2 2.2 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain tRNA-synt_1g PF09334.6 EGC32916.1 - 2.6e-16 59.2 0.9 2.8e-08 32.8 0.1 2.4 2 0 0 2 2 2 2 tRNA synthetases class I (M) tRNA-synt_1f PF01921.13 EGC32916.1 - 0.00018 20.2 0.0 0.017 13.8 0.0 2.5 2 0 0 2 2 2 2 tRNA synthetases class I (K) tRNA-synt_1 PF00133.17 EGC32916.1 - 0.0015 16.6 0.0 0.05 11.6 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) DUF883 PF05957.8 EGC32916.1 - 0.21 12.0 0.2 0.7 10.3 0.0 1.9 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF883) F-box-like PF12937.2 EGC32917.1 - 0.0017 18.0 0.5 0.023 14.4 0.0 2.5 2 0 0 2 2 2 1 F-box-like Carboxyl_trans PF01039.17 EGC32918.1 - 2.6e-191 636.2 0.0 3.1e-191 636.0 0.0 1.1 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGC32918.1 - 0.013 14.7 0.0 0.049 12.8 0.0 1.9 2 1 1 3 3 3 0 Malonate decarboxylase gamma subunit (MdcE) Longin PF13774.1 EGC32919.1 - 1.2e-26 92.0 0.1 2.1e-26 91.2 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGC32919.1 - 3.2e-25 87.5 3.3 4.8e-25 86.9 2.3 1.3 1 0 0 1 1 1 1 Synaptobrevin SRP-alpha_N PF04086.8 EGC32919.1 - 0.038 13.3 0.6 0.051 12.9 0.5 1.2 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal Ribosomal_L13e PF01294.13 EGC32919.1 - 0.12 11.8 0.1 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L13e eIF-6 PF01912.13 EGC32920.1 - 3e-80 267.9 1.2 3.7e-80 267.6 0.6 1.3 2 0 0 2 2 2 1 eIF-6 family OTU PF02338.14 EGC32921.1 - 5.7e-13 49.5 0.2 2e-12 47.7 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease DUF1840 PF08895.6 EGC32921.1 - 0.083 12.9 8.8 1.4 8.9 0.3 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1840) DUF3290 PF11694.3 EGC32921.1 - 1.4 8.6 5.7 21 4.7 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3290) p450 PF00067.17 EGC32922.1 - 5.5e-77 259.2 1.0 6.3e-77 259.0 0.7 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_15 PF00723.16 EGC32923.1 - 2.3e-14 52.8 0.0 7.4e-12 44.5 0.0 2.2 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 Suf PF05843.9 EGC32923.1 - 0.045 13.4 0.0 0.086 12.5 0.0 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Metallophos_2 PF12850.2 EGC32924.1 - 1.2e-05 25.1 0.1 3.2e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain E1_DerP2_DerF2 PF02221.10 EGC32925.1 - 5.6e-23 81.6 0.3 6.4e-23 81.4 0.2 1.0 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGC32925.1 - 0.0001 22.3 0.8 0.00058 19.8 0.6 1.8 1 1 0 1 1 1 1 ML-like domain E1_DerP2_DerF2 PF02221.10 EGC32926.1 - 4.1e-21 75.6 0.9 5.3e-21 75.2 0.6 1.1 1 0 0 1 1 1 1 ML domain TRP_N PF14558.1 EGC32926.1 - 0.0015 18.5 0.4 0.021 14.8 0.2 2.1 1 1 0 1 1 1 1 ML-like domain tRNA-synt_1 PF00133.17 EGC32927.1 - 9.8e-216 717.3 0.2 1.4e-215 716.8 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC32927.1 - 2.5e-23 82.5 0.0 4.9e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGC32927.1 - 5.7e-18 64.7 1.6 7e-06 24.9 0.1 4.2 3 1 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1e PF01406.14 EGC32927.1 - 0.00031 19.9 0.0 0.00078 18.6 0.0 1.7 1 0 0 1 1 1 1 tRNA synthetases class I (C) catalytic domain DUF2807 PF10988.3 EGC32927.1 - 0.11 12.0 1.4 0.2 11.1 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2807) DUF2510 PF10708.4 EGC32928.1 - 0.096 12.1 0.2 0.29 10.6 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2510) ketoacyl-synt PF00109.21 EGC32929.1 - 7.6e-60 202.5 0.0 2.4e-59 200.8 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC32929.1 - 7.5e-44 150.3 0.0 1.2e-43 149.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC32929.1 - 7.2e-31 106.5 0.0 5.3e-30 103.7 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC32929.1 - 2.1e-21 76.2 2.6 3e-21 75.7 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain PS-DH PF14765.1 EGC32929.1 - 4.4e-13 49.0 0.0 1e-08 34.7 0.0 2.1 1 1 1 2 2 2 2 Polyketide synthase dehydratase Methyltransf_11 PF08241.7 EGC32929.1 - 9.1e-07 29.2 0.0 7.8e-06 26.2 0.0 2.7 3 0 0 3 3 2 1 Methyltransferase domain ADH_N PF08240.7 EGC32929.1 - 2.8e-06 27.0 0.2 6.3e-06 25.9 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC32929.1 - 3.3e-06 26.8 0.0 8.9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC32929.1 - 5.4e-05 23.7 0.0 0.00018 22.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC32929.1 - 8.3e-05 21.6 0.1 0.00017 20.6 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGC32929.1 - 0.00016 21.8 0.1 0.00047 20.3 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site KR PF08659.5 EGC32929.1 - 0.014 15.0 0.0 4.3 6.9 0.0 2.4 1 1 1 2 2 2 0 KR domain TPR_MLP1_2 PF07926.7 EGC32930.1 - 0.0047 16.6 4.0 0.0064 16.2 2.7 1.2 1 0 0 1 1 1 1 TPR/MLP1/MLP2-like protein Bro-N PF02498.12 EGC32930.1 - 0.022 15.0 0.1 0.044 14.0 0.1 1.5 1 0 0 1 1 1 0 BRO family, N-terminal domain DUF4430 PF14478.1 EGC32930.1 - 0.033 14.2 0.3 0.066 13.2 0.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4430) TMCO5 PF14992.1 EGC32930.1 - 0.038 13.1 6.3 0.096 11.8 4.4 1.7 1 1 0 1 1 1 0 TMCO5 family Mago_nashi PF02792.9 EGC32930.1 - 0.05 13.2 0.9 0.084 12.5 0.5 1.5 1 1 0 1 1 1 0 Mago nashi protein DivIVA PF05103.8 EGC32930.1 - 0.11 12.4 4.7 0.41 10.7 3.2 1.9 1 1 0 1 1 1 0 DivIVA protein Seadorna_VP6 PF07407.6 EGC32930.1 - 0.12 11.0 1.4 0.14 10.8 1.0 1.1 1 0 0 1 1 1 0 Seadornavirus VP6 protein DUF904 PF06005.7 EGC32930.1 - 0.28 11.4 9.2 4.5 7.6 2.9 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF904) DUF1843 PF08898.5 EGC32930.1 - 1.4 8.9 3.8 9 6.4 0.1 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF1843) FNIP PF05725.7 EGC32931.1 - 4.2e-88 289.0 69.5 1.1e-13 50.8 2.5 10.7 7 3 6 13 13 13 12 FNIP Repeat LRR_5 PF13306.1 EGC32931.1 - 1.5e-07 31.1 6.2 0.12 12.0 0.0 4.3 2 2 3 5 5 5 4 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC32931.1 - 0.00015 21.5 14.4 1.2 9.0 0.0 8.1 5 3 2 9 9 9 2 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC32932.1 - 2.7e-173 561.7 72.6 3.5e-16 58.8 0.2 14.4 10 2 6 16 16 16 16 FNIP Repeat DUF1769 PF08588.5 EGC32932.1 - 9.1e-05 22.3 26.5 2 8.4 0.0 11.0 7 5 7 14 14 14 4 Protein of unknown function (DUF1769) MerC PF03203.9 EGC32932.1 - 0.00029 21.1 0.0 56 4.1 0.0 5.4 3 2 2 5 5 5 0 MerC mercury resistance protein DUF3215 PF11503.3 EGC32932.1 - 0.03 13.9 0.1 6.1 6.5 0.0 4.5 4 2 1 5 5 5 0 Protein of unknown function (DUF3215) EGF_CA PF07645.10 EGC32933.1 - 2.3e-09 37.0 10.7 6.8e-07 29.1 0.6 2.1 2 0 0 2 2 2 2 Calcium-binding EGF domain cEGF PF12662.2 EGC32933.1 - 2.4e-08 33.4 0.8 5.4e-08 32.3 0.5 1.6 1 0 0 1 1 1 1 Complement Clr-like EGF-like FXa_inhibition PF14670.1 EGC32933.1 - 2.2e-07 30.8 2.3 2.2e-07 30.8 1.6 2.1 2 0 0 2 2 2 1 Coagulation Factor Xa inhibitory site EGF_3 PF12947.2 EGC32933.1 - 0.0001 22.1 0.2 0.0001 22.1 0.1 2.5 2 1 0 2 2 2 1 EGF domain hEGF PF12661.2 EGC32933.1 - 0.053 13.6 0.9 0.15 12.2 0.6 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF EGF PF00008.22 EGC32933.1 - 0.084 12.8 0.7 0.084 12.8 0.5 2.5 2 1 0 2 2 2 0 EGF-like domain TIL PF01826.12 EGC32933.1 - 0.92 9.6 8.0 0.33 11.0 2.0 2.1 1 1 1 2 2 2 0 Trypsin Inhibitor like cysteine rich domain DUF247 PF03140.10 EGC32934.1 - 0.0072 15.3 0.1 0.0078 15.2 0.1 1.0 1 0 0 1 1 1 1 Plant protein of unknown function Dimer_Tnp_hAT PF05699.9 EGC32935.1 - 1.7e-16 59.6 0.5 2.2e-16 59.2 0.3 1.1 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TatD_DNase PF01026.16 EGC32936.1 - 4.2e-63 212.9 0.0 4.9e-63 212.6 0.0 1.0 1 0 0 1 1 1 1 TatD related DNase Amidohydro_2 PF04909.9 EGC32936.1 - 0.00012 21.7 0.0 0.001 18.6 0.0 2.4 1 1 0 1 1 1 1 Amidohydrolase Fz PF01392.17 EGC32937.1 - 2.7e-05 24.5 1.4 2.7e-05 24.5 1.0 1.7 2 0 0 2 2 2 1 Fz domain Mei5 PF10376.4 EGC32937.1 - 0.46 9.9 12.0 0.68 9.4 8.3 1.2 1 0 0 1 1 1 0 Double-strand recombination repair protein Abhydrolase_6 PF12697.2 EGC32938.1 - 7.9e-16 58.6 0.0 1.3e-15 57.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC32938.1 - 3.2e-13 49.7 0.1 5e-13 49.1 0.1 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC32938.1 - 9.8e-05 22.1 0.0 0.00015 21.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC32938.1 - 0.00021 20.6 0.0 0.0004 19.6 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family DUF2920 PF11144.3 EGC32938.1 - 0.00056 19.0 0.1 0.00095 18.2 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2920) Ndr PF03096.9 EGC32938.1 - 0.046 12.2 0.0 0.079 11.4 0.0 1.3 1 0 0 1 1 1 0 Ndr family TPR_11 PF13414.1 EGC32939.1 - 2.7e-35 119.8 5.0 1.4e-06 27.8 0.1 8.3 6 2 2 9 9 9 7 TPR repeat TPR_2 PF07719.12 EGC32939.1 - 3.1e-27 92.2 3.4 0.015 15.1 0.0 12.0 12 0 0 12 12 12 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGC32939.1 - 2e-23 82.1 5.2 3.4e-07 30.0 0.1 7.7 6 1 1 7 7 7 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGC32939.1 - 2.6e-20 70.5 15.2 0.0041 16.8 0.0 11.2 11 1 1 12 12 12 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGC32939.1 - 4.8e-18 63.9 11.4 0.011 15.3 0.0 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGC32939.1 - 2.5e-17 62.9 1.4 0.00021 21.5 0.0 7.2 7 1 1 8 8 8 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGC32939.1 - 1.1e-13 51.4 0.0 0.068 13.8 0.1 6.9 7 2 2 9 9 7 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC32939.1 - 1.2e-12 47.7 16.6 1.8e-05 24.7 0.0 7.1 5 3 2 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGC32939.1 - 2.6e-12 46.2 0.0 0.16 12.6 0.0 9.2 8 2 3 11 11 9 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC32939.1 - 6.4e-09 35.3 7.4 0.039 14.1 0.0 8.6 11 0 0 11 11 8 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC32939.1 - 1.1e-08 35.0 8.7 2.3 8.8 0.0 8.8 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC32939.1 - 8.8e-08 31.3 2.7 2 8.4 0.0 7.9 9 0 0 9 9 9 2 Tetratricopeptide repeat TPR_20 PF14561.1 EGC32939.1 - 1.8e-05 24.7 2.5 1.5 8.9 0.0 5.8 6 1 1 7 7 6 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC32939.1 - 4.2e-05 23.3 0.2 3.4 7.5 0.0 5.3 6 1 0 7 7 5 1 Tetratricopeptide repeat BTAD PF03704.12 EGC32939.1 - 0.00013 22.2 0.4 0.32 11.2 0.0 3.5 4 0 0 4 4 4 1 Bacterial transcriptional activator domain TPR_15 PF13429.1 EGC32939.1 - 0.00013 21.1 0.1 0.1 11.6 0.2 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC32939.1 - 0.00074 19.3 3.4 47 4.0 0.0 6.8 8 0 0 8 8 8 0 Tetratricopeptide repeat Foie-gras_1 PF11817.3 EGC32939.1 - 0.0021 17.5 5.9 1.5 8.2 0.1 4.9 5 1 1 6 6 6 1 Foie gras liver health family 1 Alkyl_sulf_dimr PF14863.1 EGC32939.1 - 0.045 13.9 0.2 7.1 6.8 0.0 3.5 5 0 0 5 5 3 0 Alkyl sulfatase dimerisation LMBR1 PF04791.11 EGC32939.1 - 0.42 9.1 3.5 0.75 8.3 2.4 1.4 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF647 PF04884.9 EGC32940.1 - 3e-78 262.4 1.9 3.8e-78 262.1 1.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Metallophos_C PF14008.1 EGC32941.1 - 4.8e-14 52.1 0.8 3.4e-13 49.4 0.5 2.4 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EGC32941.1 - 6.7e-12 45.2 5.3 1.4e-11 44.1 3.6 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase DUF4315 PF14193.1 EGC32942.1 - 0.0078 16.1 1.7 0.009 15.9 1.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4315) DUF1227 PF06777.6 EGC32942.1 - 0.053 13.2 0.1 0.056 13.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1227) PPP1R35_C PF15503.1 EGC32942.1 - 0.08 12.4 0.0 0.08 12.4 0.0 1.1 1 0 0 1 1 1 0 Protein phosphatase 1 regulatory subunit 35 C-terminus Metallophos PF00149.23 EGC32943.1 - 4.6e-13 49.0 6.0 1.2e-11 44.4 4.2 2.4 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC32943.1 - 8e-06 25.7 0.1 1.4e-05 25.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain ArabFuran-catal PF09206.6 EGC32943.1 - 0.13 11.1 0.8 0.62 8.9 0.3 1.9 2 0 0 2 2 2 0 Alpha-L-arabinofuranosidase B, catalytic RRM_1 PF00076.17 EGC32944.1 - 5.3e-08 32.3 0.1 4.2e-07 29.4 0.0 2.3 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Rad52_Rad22 PF04098.10 EGC32944.1 - 1.2e-07 31.6 0.8 2e-07 30.8 0.6 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein RRM_6 PF14259.1 EGC32944.1 - 2.5e-07 30.5 0.0 4.6e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Gp_dh_N PF00044.19 EGC32944.1 - 0.097 12.6 1.6 0.19 11.7 0.7 1.7 1 1 1 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain Ribosomal_S9 PF00380.14 EGC32945.1 - 1.6e-38 131.6 0.6 1.8e-38 131.4 0.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S9/S16 DUF3430 PF11912.3 EGC32947.1 - 1.2e-28 100.4 27.1 1.3e-28 100.2 18.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) V-ATPase_C PF03223.10 EGC32948.1 - 2.9e-117 391.7 6.5 3.3e-117 391.5 4.5 1.0 1 0 0 1 1 1 1 V-ATPase subunit C DZR PF12773.2 EGC32949.1 - 0.093 12.5 3.0 0.35 10.7 2.1 2.0 1 1 0 1 1 1 0 Double zinc ribbon Prok-RING_4 PF14447.1 EGC32949.1 - 0.33 10.5 3.7 0.59 9.7 2.6 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF766 PF05571.7 EGC32949.1 - 0.63 9.2 3.7 0.81 8.9 2.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF766) zf-C3HC4_2 PF13923.1 EGC32949.1 - 2.9 7.9 11.4 2.8 8.0 5.8 2.3 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 EGC32949.1 - 7.7 6.9 10.5 3.7 8.0 0.0 3.5 2 1 1 3 3 3 0 TRAF-type zinc finger LysM PF01476.15 EGC32950.1 - 3.2e-07 30.1 1.1 0.02 14.8 0.0 2.4 2 0 0 2 2 2 2 LysM domain DPBB_1 PF03330.13 EGC32950.1 - 4.3e-07 29.8 0.1 1.1e-06 28.5 0.1 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel SapB_2 PF03489.12 EGC32950.1 - 0.054 13.5 0.0 9.3 6.3 0.0 2.4 2 0 0 2 2 2 0 Saposin-like type B, region 2 Herpes_U30 PF04523.8 EGC32950.1 - 0.2 9.0 0.0 0.35 8.2 0.0 1.3 1 0 0 1 1 1 0 Herpes virus tegument protein U30 KOW PF00467.24 EGC32951.1 - 0.00045 19.8 2.6 0.00045 19.8 1.8 2.3 3 1 0 3 3 3 1 KOW motif Methyltrans_RNA PF04452.9 EGC32951.1 - 0.037 13.1 0.3 0.059 12.4 0.1 1.3 1 1 0 1 1 1 0 RNA methyltransferase U-box PF04564.10 EGC32952.1 - 3.8e-14 52.4 0.3 7.7e-14 51.4 0.2 1.5 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EGC32952.1 - 5.8e-09 35.3 0.3 1.2e-08 34.2 0.2 1.5 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit Acetyltransf_1 PF00583.19 EGC32952.1 - 5e-07 29.6 0.0 1e-06 28.6 0.0 1.6 1 1 1 2 2 2 1 Acetyltransferase (GNAT) family zf-C3HC4_2 PF13923.1 EGC32952.1 - 6e-07 29.3 0.3 1.3e-06 28.2 0.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC32952.1 - 1.6e-06 28.1 0.2 4.5e-06 26.6 0.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Acetyltransf_7 PF13508.1 EGC32952.1 - 3.2e-06 27.2 0.0 1.7e-05 24.9 0.0 2.1 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-RING_2 PF13639.1 EGC32952.1 - 4.1e-06 26.5 0.1 8.7e-06 25.4 0.0 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC32952.1 - 0.00011 21.7 0.2 0.00022 20.7 0.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC32952.1 - 0.00034 20.2 1.8 0.0011 18.6 0.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger Acetyltransf_10 PF13673.1 EGC32952.1 - 0.0008 19.5 0.0 0.072 13.2 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Rtf2 PF04641.7 EGC32952.1 - 0.002 17.3 0.1 0.0036 16.5 0.1 1.3 1 0 0 1 1 1 1 Rtf2 RING-finger zf-RING_5 PF14634.1 EGC32952.1 - 0.0058 16.3 0.1 0.014 15.1 0.1 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC32952.1 - 0.007 16.1 0.1 0.013 15.2 0.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGC32952.1 - 0.008 15.8 0.1 0.014 15.0 0.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC32952.1 - 0.013 15.3 0.3 0.093 12.6 0.3 2.3 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING Acetyltransf_9 PF13527.1 EGC32952.1 - 0.016 15.0 0.0 1.8 8.4 0.0 2.3 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC32952.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Isochorismatase PF00857.15 EGC32953.1 - 3e-17 63.1 0.0 3.7e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family Isochorismatase PF00857.15 EGC32954.1 - 5.8e-31 107.7 0.1 6.9e-31 107.4 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family DUF2150 PF09920.4 EGC32954.1 - 0.033 13.7 0.2 0.05 13.1 0.1 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2150) TFIID-18kDa PF02269.11 EGC32954.1 - 0.056 13.2 0.2 0.13 12.0 0.2 1.7 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit priB_priC PF07445.7 EGC32954.1 - 0.084 12.3 0.1 0.18 11.2 0.1 1.7 1 1 0 1 1 1 0 Primosomal replication protein priB and priC THF_DHG_CYH_C PF02882.14 EGC32955.1 - 1e-73 245.7 1.8 1.7e-73 245.0 0.5 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain THF_DHG_CYH PF00763.18 EGC32955.1 - 6.9e-40 135.7 3.4 6.9e-40 135.7 2.3 1.7 2 0 0 2 2 2 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Ligase_CoA PF00549.14 EGC32955.1 - 0.14 11.7 0.7 19 4.8 0.0 2.9 2 2 1 3 3 3 0 CoA-ligase DSPc PF00782.15 EGC32956.1 - 7.8e-07 28.7 0.0 1.2e-06 28.0 0.0 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGC32956.1 - 0.023 14.9 0.0 0.04 14.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EGC32956.1 - 0.049 12.9 0.0 0.088 12.1 0.0 1.4 1 0 0 1 1 1 0 Tyrosine phosphatase family VPR PF00522.13 EGC32956.1 - 0.13 12.1 0.0 0.2 11.4 0.0 1.3 1 0 0 1 1 1 0 VPR/VPX protein Beach PF02138.13 EGC32957.1 - 1.1e-110 369.4 4.7 2.4e-110 368.2 3.2 1.7 1 0 0 1 1 1 1 Beige/BEACH domain PH_BEACH PF14844.1 EGC32957.1 - 4.9e-20 71.3 0.0 1.7e-19 69.5 0.0 2.1 1 0 0 1 1 1 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGC32957.1 - 2e-13 50.8 0.0 2.9e-12 47.1 0.0 2.6 2 0 0 2 2 2 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EGC32957.1 - 8.8e-07 28.5 13.5 0.0002 21.0 0.2 4.9 5 0 0 5 5 5 2 WD domain, G-beta repeat ParBc PF02195.13 EGC32958.1 - 5.5e-11 42.4 0.0 6.6e-11 42.1 0.0 1.1 1 0 0 1 1 1 1 ParB-like nuclease domain HD PF01966.17 EGC32959.1 - 0.0002 21.3 0.0 0.0003 20.8 0.0 1.3 1 0 0 1 1 1 1 HD domain Mer2 PF09074.5 EGC32959.1 - 3.6 7.4 6.6 13 5.7 1.0 2.2 2 0 0 2 2 2 0 Mer2 IncFII_repA PF02387.10 EGC32960.1 - 0.018 14.2 0.1 0.025 13.7 0.1 1.1 1 0 0 1 1 1 0 IncFII RepA protein family Xpo1 PF08389.7 EGC32961.1 - 7.8e-36 123.2 2.7 7.8e-36 123.2 1.9 4.0 3 1 0 3 3 3 1 Exportin 1-like protein IBN_N PF03810.14 EGC32961.1 - 0.00079 19.3 2.5 0.35 10.8 0.1 4.5 4 1 1 5 5 5 2 Importin-beta N-terminal domain Ribosomal_L9_N PF01281.14 EGC32962.1 - 4.8e-18 64.1 0.3 9.8e-18 63.1 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L9, N-terminal domain Ribosomal_L9_C PF03948.9 EGC32962.1 - 4e-05 23.6 0.6 8.9e-05 22.4 0.1 1.7 2 0 0 2 2 2 1 Ribosomal protein L9, C-terminal domain zf-HC5HC2H_2 PF13832.1 EGC32963.1 - 9.1e-23 80.3 4.0 9.1e-23 80.3 2.8 2.6 2 0 0 2 2 2 1 PHD-zinc-finger like domain Bromodomain PF00439.20 EGC32963.1 - 1.6e-16 59.9 1.5 5.7e-16 58.2 1.1 2.1 1 0 0 1 1 1 1 Bromodomain zf-HC5HC2H PF13771.1 EGC32963.1 - 1.9e-16 59.9 2.0 1.9e-16 59.9 1.4 3.4 3 0 0 3 3 3 1 PHD-like zinc-binding domain PHD_2 PF13831.1 EGC32963.1 - 9.1e-14 50.4 3.2 9.1e-14 50.4 2.2 2.9 3 0 0 3 3 3 1 PHD-finger EPL1 PF10513.4 EGC32963.1 - 2.5e-12 47.3 47.6 2.5e-12 47.3 33.0 7.2 3 2 0 3 3 3 1 Enhancer of polycomb-like PHD PF00628.24 EGC32963.1 - 3.6e-11 42.5 25.4 3.6e-09 36.1 4.3 3.5 3 1 0 3 3 3 2 PHD-finger C1_1 PF00130.17 EGC32963.1 - 0.017 14.8 0.7 0.017 14.8 0.5 3.3 2 1 1 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING-like PF08746.6 EGC32963.1 - 0.034 14.1 20.1 0.022 14.7 2.7 3.0 2 1 1 3 3 3 0 RING-like domain zf-RING_2 PF13639.1 EGC32963.1 - 4.2 7.2 19.1 5.6 6.8 1.7 2.6 2 0 0 2 2 2 0 Ring finger domain DNA_ligase_A_M PF01068.16 EGC32964.1 - 1.2e-52 178.2 0.1 3.5e-52 176.7 0.1 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGC32964.1 - 3.4e-33 114.9 1.5 8.3e-33 113.6 0.1 2.3 2 0 0 2 2 2 1 DNA ligase N terminus BRCT PF00533.21 EGC32964.1 - 1.3e-16 60.4 12.2 5e-12 45.7 0.3 4.4 4 0 0 4 4 4 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_A_C PF04679.10 EGC32964.1 - 2.8e-16 59.6 0.0 8.1e-16 58.2 0.0 1.9 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region PTCB-BRCT PF12738.2 EGC32964.1 - 1e-12 47.6 0.1 6.9e-05 22.6 0.0 2.8 2 0 0 2 2 2 2 twin BRCT domain ABA_GPCR PF12430.3 EGC32965.1 - 2.2e-55 186.8 13.4 2.2e-55 186.8 9.3 1.8 2 0 0 2 2 2 1 Abscisic acid G-protein coupled receptor DUF3735 PF12537.3 EGC32965.1 - 1.8e-22 79.1 0.1 6.6e-22 77.3 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3735) DUF904 PF06005.7 EGC32965.1 - 0.034 14.4 2.3 0.64 10.3 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF904) DUF465 PF04325.8 EGC32965.1 - 0.23 11.1 4.8 0.13 12.0 1.7 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF465) Phage-scaffold PF09306.5 EGC32966.1 - 0.038 13.1 0.0 0.07 12.2 0.0 1.3 1 0 0 1 1 1 0 Bacteriophage, scaffolding protein DUF911 PF06023.7 EGC32967.1 - 0.13 11.4 0.1 0.26 10.4 0.0 1.4 1 0 0 1 1 1 0 Archaeal protein of unknown function (DUF911) Glucodextran_N PF09137.6 EGC32968.1 - 0.043 13.0 0.3 0.2 10.8 0.0 1.8 1 1 1 2 2 2 0 Glucodextranase, domain N AhpC-TSA PF00578.16 EGC32969.1 - 4.2e-42 142.7 0.1 4.9e-42 142.5 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC32969.1 - 1.5e-25 89.4 0.1 1.7e-25 89.2 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGC32969.1 - 0.00014 21.7 0.0 0.00024 21.0 0.0 1.3 1 1 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.1 EGC32969.1 - 0.027 14.5 0.0 0.045 13.8 0.0 1.3 1 0 0 1 1 1 0 Thioredoxin-like YwhD PF08741.5 EGC32969.1 - 0.11 11.8 0.0 0.14 11.5 0.0 1.1 1 0 0 1 1 1 0 YwhD family Ribosomal_S7e PF01251.13 EGC32970.1 - 9.9e-79 263.2 7.8 1.1e-78 263.0 5.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S7e Snf7 PF03357.16 EGC32971.1 - 1.4e-40 138.4 17.5 1.6e-40 138.2 12.1 1.0 1 0 0 1 1 1 1 Snf7 ORF6C PF10552.4 EGC32971.1 - 0.016 14.9 7.2 0.29 10.8 0.6 2.4 2 0 0 2 2 2 0 ORF6C domain DUF285 PF03382.9 EGC32971.1 - 0.03 13.8 3.4 0.053 13.0 1.5 1.9 2 0 0 2 2 2 0 Mycoplasma protein of unknown function, DUF285 Prefoldin PF02996.12 EGC32971.1 - 0.031 13.9 0.2 0.031 13.9 0.2 3.3 1 1 2 3 3 3 0 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGC32971.1 - 0.039 13.6 11.4 0.074 12.7 7.9 1.5 1 0 0 1 1 1 0 TPR/MLP1/MLP2-like protein Phage_lysozyme PF00959.14 EGC32971.1 - 0.069 13.4 2.5 0.15 12.3 1.8 1.6 1 1 0 1 1 1 0 Phage lysozyme Evr1_Alr PF04777.8 EGC32971.1 - 0.075 12.9 0.2 0.13 12.1 0.2 1.4 1 0 0 1 1 1 0 Erv1 / Alr family DUF2443 PF10398.4 EGC32971.1 - 0.08 12.7 2.5 1.4 8.7 0.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2443) DUF4559 PF15112.1 EGC32971.1 - 0.14 11.3 9.8 0.18 10.9 6.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Cauli_DNA-bind PF03310.8 EGC32971.1 - 0.18 11.6 2.9 0.1 12.4 0.5 1.7 2 0 0 2 2 2 0 Caulimovirus DNA-binding protein Pup PF05639.6 EGC32971.1 - 0.22 12.0 4.6 0.61 10.6 3.2 1.9 1 1 0 1 1 1 0 Pup-like protein DUF4140 PF13600.1 EGC32971.1 - 0.24 11.8 2.8 1.8 9.0 0.0 2.8 2 1 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) OmpH PF03938.9 EGC32971.1 - 0.33 10.8 21.0 0.14 12.1 7.6 2.1 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) IncA PF04156.9 EGC32971.1 - 0.73 9.4 9.9 0.45 10.0 1.6 2.1 1 1 1 2 2 2 0 IncA protein Atg14 PF10186.4 EGC32971.1 - 1.5 7.7 9.5 2.1 7.2 6.6 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF848 PF05852.6 EGC32971.1 - 1.6 8.5 7.2 1.4 8.8 3.9 1.7 1 1 0 2 2 2 0 Gammaherpesvirus protein of unknown function (DUF848) DUF972 PF06156.8 EGC32971.1 - 8.3 6.8 13.0 3.4 8.0 2.3 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF972) DNA_ligase_A_N PF04675.9 EGC32972.1 - 0.04 13.7 0.1 0.067 13.0 0.1 1.3 1 0 0 1 1 1 0 DNA ligase N terminus DUF155 PF02582.9 EGC32973.1 - 8.2e-31 107.2 0.7 8.2e-31 107.2 0.5 2.3 2 0 0 2 2 2 1 Uncharacterised ACR, YagE family COG1723 Ctr PF04145.10 EGC32973.1 - 0.14 12.2 2.0 6.4 6.8 0.0 2.3 2 0 0 2 2 2 0 Ctr copper transporter family Actin PF00022.14 EGC32974.1 - 9.6e-85 284.3 0.0 1.3e-84 283.9 0.0 1.1 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC32974.1 - 3.4e-05 22.6 0.1 0.00011 20.9 0.1 1.8 1 1 0 1 1 1 1 MreB/Mbl protein Bundlin PF05307.6 EGC32974.1 - 0.02 14.7 0.1 0.044 13.6 0.1 1.5 1 0 0 1 1 1 0 Bundlin K_trans PF02705.11 EGC32975.1 - 9.7e-188 624.8 23.2 1.2e-187 624.5 16.1 1.1 1 0 0 1 1 1 1 K+ potassium transporter CAF-1_p150 PF11600.3 EGC32976.1 - 0.0076 15.6 6.9 0.0076 15.6 4.8 1.4 2 0 0 2 2 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal RNA_pol_3_Rpc31 PF11705.3 EGC32976.1 - 0.066 13.1 34.1 2 8.2 23.6 2.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 TFIIA PF03153.8 EGC32976.1 - 0.11 12.3 6.9 0.13 12.1 4.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Myc_N PF01056.13 EGC32976.1 - 0.28 10.3 4.3 0.39 9.8 3.0 1.2 1 0 0 1 1 1 0 Myc amino-terminal region DUF3295 PF11702.3 EGC32976.1 - 0.3 10.0 5.1 0.37 9.7 3.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Pox_Ag35 PF03286.9 EGC32976.1 - 0.46 9.9 8.6 0.72 9.3 5.9 1.3 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Nop14 PF04147.7 EGC32976.1 - 3 5.6 13.6 3.6 5.3 9.4 1.2 1 0 0 1 1 1 0 Nop14-like family DUF3295 PF11702.3 EGC32977.1 - 1.9 7.3 4.6 2.4 7.0 3.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3295) Nop14 PF04147.7 EGC32977.1 - 4.1 5.1 16.1 1.3 6.8 9.2 1.6 2 0 0 2 2 2 0 Nop14-like family Transket_pyr PF02779.19 EGC32978.1 - 3.6e-67 225.2 0.0 6e-67 224.5 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGC32978.1 - 2.5e-60 203.7 0.1 3.6e-60 203.2 0.1 1.2 1 0 0 1 1 1 1 Dehydrogenase E1 component GNT-I PF03071.10 EGC32979.1 - 1e-82 278.0 12.0 1.3e-82 277.6 8.3 1.3 1 1 0 1 1 1 1 GNT-I family TMF_DNA_bd PF12329.3 EGC32979.1 - 0.0011 18.7 6.0 0.0027 17.4 4.2 1.7 1 1 0 1 1 1 1 TATA element modulatory factor 1 DNA binding DUF4446 PF14584.1 EGC32979.1 - 0.013 15.3 1.8 0.032 14.0 1.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4446) DUF3450 PF11932.3 EGC32979.1 - 0.014 14.6 0.2 0.028 13.6 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Cortex-I_coil PF09304.5 EGC32979.1 - 0.025 14.6 3.1 0.054 13.5 2.1 1.5 1 0 0 1 1 1 0 Cortexillin I, coiled coil RRM_1 PF00076.17 EGC32981.1 - 3.9e-11 42.4 0.2 2.4e-05 23.8 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC32981.1 - 4.9e-10 39.1 0.4 9.7e-06 25.3 0.0 2.7 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC32981.1 - 1.6e-06 28.0 0.0 0.011 15.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DivIC PF04977.10 EGC32981.1 - 0.013 14.9 0.6 0.013 14.9 0.4 2.7 3 0 0 3 3 3 0 Septum formation initiator Aldedh PF00171.17 EGC32982.1 - 3.5e-166 553.1 0.0 4e-166 552.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGC32982.1 - 0.00011 21.0 0.0 0.00017 20.4 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF3430 PF11912.3 EGC32983.1 - 1.3e-19 70.8 24.1 1.6e-19 70.6 16.7 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Ist1 PF03398.9 EGC32985.1 - 1.9e-52 177.0 5.9 2.5e-52 176.6 4.1 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway PAT1 PF09770.4 EGC32985.1 - 0.13 10.4 38.9 0.18 9.9 27.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 FNIP PF05725.7 EGC32986.1 - 2.6e-180 584.2 69.4 8.6e-16 57.6 0.2 14.3 5 2 9 17 17 17 16 FNIP Repeat DUF1769 PF08588.5 EGC32986.1 - 1.2e-06 28.2 23.5 7.2 6.6 0.0 12.1 6 5 8 14 14 14 3 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC32986.1 - 0.014 15.3 0.0 60 3.6 0.0 5.8 7 1 1 8 8 8 0 Phage minor tail protein PyocinActivator PF11112.3 EGC32986.1 - 0.055 13.3 0.2 36 4.2 0.0 4.7 4 1 1 5 5 5 0 Pyocin activator protein PrtN Oxidored_q4 PF00507.14 EGC32986.1 - 0.074 12.8 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 FAD_binding_1 PF00667.15 EGC32987.1 - 1.1e-44 152.5 0.0 1.9e-44 151.7 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGC32987.1 - 3.8e-27 95.0 0.0 6.2e-27 94.3 0.0 1.3 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGC32987.1 - 1.9e-15 57.3 0.1 5.5e-15 55.8 0.0 1.9 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGC32987.1 - 0.008 16.1 0.0 2 8.4 0.1 2.4 1 1 1 2 2 2 2 Flavodoxin domain DUF2392 PF10288.4 EGC32987.1 - 0.85 9.9 7.6 1.5 9.2 0.4 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF2392) DUF3402 PF11882.3 EGC32988.1 - 3e-55 187.9 21.9 3e-55 187.9 15.2 2.5 2 1 0 2 2 2 1 Domain of unknown function (DUF3402) N1221 PF07923.8 EGC32988.1 - 2.5e-21 75.7 17.5 2.2e-13 49.6 4.5 2.9 3 1 0 3 3 3 2 N1221-like protein DUF3484 PF11983.3 EGC32988.1 - 0.81 10.5 5.4 30 5.5 0.1 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3484) dCMP_cyt_deam_1 PF00383.17 EGC32989.1 - 1.5e-22 79.1 0.3 3e-22 78.2 0.2 1.5 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Endonuc_BglI PF14562.1 EGC32989.1 - 0.04 12.7 0.8 3.3 6.4 0.0 2.2 2 0 0 2 2 2 0 Restriction endonuclease BglI Bd3614-deam PF14439.1 EGC32989.1 - 0.5 10.2 3.4 2.5 7.9 2.4 2.0 1 1 0 1 1 1 0 Bd3614-like deaminase MAS20 PF02064.10 EGC32989.1 - 0.58 10.0 4.7 3 7.7 0.3 2.3 2 0 0 2 2 2 0 MAS20 protein import receptor CTP_transf_2 PF01467.21 EGC32990.1 - 0.001 19.1 0.0 0.0024 17.9 0.0 1.7 1 0 0 1 1 1 1 Cytidylyltransferase Peptidase_S24 PF00717.18 EGC32991.1 - 0.018 14.6 0.0 0.049 13.2 0.0 1.8 1 0 0 1 1 1 0 Peptidase S24-like Pox_RNA_Pol_19 PF05320.7 EGC32991.1 - 0.036 13.8 3.4 0.049 13.3 2.4 1.2 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Gal-3-0_sulfotr PF06990.6 EGC32992.1 - 0.0012 17.5 0.1 0.0033 16.1 0.1 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_2 PF03567.9 EGC32993.1 - 3e-11 43.5 2.9 8.9e-11 41.9 2.0 1.8 1 0 0 1 1 1 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 EGC32993.1 - 0.0005 18.8 0.4 0.0011 17.6 0.3 1.7 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase DUF4179 PF13786.1 EGC32993.1 - 0.025 14.7 4.5 0.064 13.4 3.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) Sulfotransfer_2 PF03567.9 EGC32994.1 - 1.6e-10 41.1 0.3 1.6e-10 41.1 0.2 2.0 2 0 0 2 2 2 1 Sulfotransferase family Gal-3-0_sulfotr PF06990.6 EGC32994.1 - 0.0011 17.6 0.0 0.0026 16.4 0.0 1.6 1 1 0 1 1 1 1 Galactose-3-O-sulfotransferase Sulfotransfer_1 PF00685.22 EGC32994.1 - 0.06 12.6 1.9 0.076 12.2 0.1 2.0 1 1 0 2 2 2 0 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EGC32994.1 - 0.12 13.3 0.1 0.39 11.6 0.1 1.7 1 1 0 1 1 1 0 Sulfotransferase family 7TM_GPCR_Srd PF10317.4 EGC32994.1 - 0.18 10.7 0.8 0.26 10.2 0.5 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd Tetraspannin PF00335.15 EGC32994.1 - 0.87 8.8 4.3 2.5 7.3 3.0 1.8 1 1 0 1 1 1 0 Tetraspanin family 2OG-FeII_Oxy PF03171.15 EGC32995.1 - 0.00011 22.4 0.0 0.00032 20.9 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGC32995.1 - 0.00022 21.6 0.0 0.0005 20.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily IncA PF04156.9 EGC32996.1 - 0.0059 16.2 13.6 0.0059 16.2 9.4 3.2 3 0 0 3 3 3 2 IncA protein SbcD_C PF12320.3 EGC32996.1 - 0.014 15.4 0.9 0.014 15.4 0.6 4.3 3 1 1 4 4 4 0 Type 5 capsule protein repressor C-terminal domain Spc7 PF08317.6 EGC32996.1 - 0.019 13.6 47.8 0.046 12.3 3.3 3.6 3 1 0 3 3 3 0 Spc7 kinetochore protein OmpH PF03938.9 EGC32996.1 - 0.022 14.7 50.5 0.97 9.3 20.2 4.2 3 1 0 3 3 3 0 Outer membrane protein (OmpH-like) PMEI PF04043.10 EGC32996.1 - 0.071 13.0 5.2 0.16 11.8 0.5 3.0 3 0 0 3 3 3 0 Plant invertase/pectin methylesterase inhibitor Ribosomal_L17 PF01196.14 EGC32996.1 - 0.14 12.7 6.0 0.12 12.9 0.3 3.1 2 0 0 2 2 2 0 Ribosomal protein L17 Retrotrans_gag PF03732.12 EGC32996.1 - 0.17 12.0 4.8 0.55 10.3 0.2 3.3 3 0 0 3 3 3 0 Retrotransposon gag protein NAAA-beta PF15508.1 EGC32996.1 - 0.17 12.2 6.4 9 6.7 0.0 4.1 3 1 1 4 4 4 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase RHSP PF07999.6 EGC32996.1 - 0.54 8.8 8.4 0.049 12.2 2.6 1.6 2 0 0 2 2 2 0 Retrotransposon hot spot protein ERM PF00769.14 EGC32996.1 - 2.9 7.3 37.9 0.25 10.8 13.2 2.9 3 0 0 3 3 3 0 Ezrin/radixin/moesin family Syntaxin-6_N PF09177.6 EGC32996.1 - 3.9 7.9 28.6 0.2 12.0 1.0 4.8 3 1 3 6 6 6 0 Syntaxin 6, N-terminal COG2 PF06148.6 EGC32996.1 - 3.9 7.3 27.8 4.2 7.2 2.5 4.5 3 1 1 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2422 PF10337.4 EGC32996.1 - 7.7 5.1 10.8 0.93 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) NADH-u_ox-rdase PF10785.4 EGC32997.1 - 1.7e-09 37.8 0.3 2.2e-09 37.4 0.2 1.2 1 0 0 1 1 1 1 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit FNIP PF05725.7 EGC32999.1 - 3.8e-55 183.5 56.9 2.4e-15 56.2 0.4 6.3 2 2 3 7 7 7 7 FNIP Repeat LRR_5 PF13306.1 EGC32999.1 - 0.034 13.8 5.2 1.1 8.9 0.3 2.7 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) DNA_primase_lrg PF04104.9 EGC33000.1 - 6e-65 219.0 0.4 1e-64 218.3 0.3 1.4 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase, large subunit Ribosomal_L7Ae PF01248.21 EGC33001.1 - 8.3e-22 76.5 0.0 9.7e-22 76.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family AAA_22 PF13401.1 EGC33002.1 - 0.042 13.9 0.0 0.15 12.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain DUF504 PF04457.7 EGC33003.1 - 0.00024 21.1 0.1 0.013 15.5 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function (DUF504) PA26 PF04636.8 EGC33003.1 - 0.07 11.8 2.6 0.089 11.4 1.8 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) LAP1C PF05609.7 EGC33003.1 - 0.44 9.1 7.7 0.58 8.7 5.4 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) Presenilin PF01080.12 EGC33003.1 - 7.9 5.1 6.9 10 4.7 4.8 1.2 1 0 0 1 1 1 0 Presenilin Ras PF00071.17 EGC33004.1 - 3.3e-43 146.8 0.7 3.9e-43 146.6 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33004.1 - 4.5e-14 52.9 0.0 7.8e-14 52.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC33004.1 - 9.7e-06 24.9 0.2 1.1e-05 24.7 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC33004.1 - 2.5e-05 23.5 0.3 3.2e-05 23.1 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC33004.1 - 0.00028 20.3 0.2 0.023 14.1 0.0 2.1 1 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_5 PF07728.9 EGC33004.1 - 0.014 15.0 0.0 0.02 14.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) PduV-EutP PF10662.4 EGC33004.1 - 0.021 14.3 0.1 0.24 10.8 0.0 2.3 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation DUF613 PF04764.7 EGC33004.1 - 0.028 14.3 0.3 0.12 12.2 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF613) cobW PF02492.14 EGC33004.1 - 0.036 13.5 0.0 0.91 8.9 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_14 PF13173.1 EGC33004.1 - 0.049 13.5 0.1 0.091 12.6 0.1 1.4 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGC33004.1 - 0.077 12.9 0.0 0.1 12.5 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EGC33004.1 - 0.084 12.4 0.1 0.12 11.9 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGC33004.1 - 0.13 12.4 0.0 0.26 11.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain GAS PF13851.1 EGC33005.1 - 0.0022 17.2 3.2 0.0022 17.2 2.2 2.9 2 1 0 3 3 3 1 Growth-arrest specific micro-tubule binding Syntaxin PF00804.20 EGC33005.1 - 0.011 15.8 3.1 0.011 15.8 2.2 3.0 2 1 1 3 3 3 0 Syntaxin ABC_trans_N PF14510.1 EGC33005.1 - 0.02 14.9 0.2 0.038 14.0 0.1 1.4 1 0 0 1 1 1 0 ABC-transporter extracellular N-terminal TPR_MLP1_2 PF07926.7 EGC33005.1 - 0.37 10.5 13.0 0.047 13.4 1.5 2.9 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein CCDC155 PF14662.1 EGC33005.1 - 0.53 9.8 22.2 0.52 9.8 3.2 3.6 2 2 2 4 4 4 0 Coiled-coil region of CCDC155 TMF_DNA_bd PF12329.3 EGC33005.1 - 0.65 9.8 22.8 0.39 10.5 5.0 4.2 3 1 1 4 4 4 0 TATA element modulatory factor 1 DNA binding Occludin_ELL PF07303.8 EGC33005.1 - 1.2 9.9 6.1 0.58 10.9 1.4 2.5 3 0 0 3 3 3 0 Occludin homology domain MutS_IV PF05190.13 EGC33005.1 - 1.2 9.3 9.6 2.9 8.1 0.3 4.0 3 1 1 4 4 4 0 MutS family domain IV Filo_VP35 PF02097.10 EGC33005.1 - 1.2 8.2 6.2 0.17 11.0 0.5 2.0 1 1 1 2 2 2 0 Filoviridae VP35 Reo_sigmaC PF04582.7 EGC33005.1 - 1.9 7.5 5.7 0.6 9.2 1.0 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein TMF_TATA_bd PF12325.3 EGC33005.1 - 2.1 8.1 15.5 0.041 13.6 4.1 2.7 2 1 1 3 3 3 0 TATA element modulatory factor 1 TATA binding HOOK PF05622.7 EGC33005.1 - 2.2 6.0 18.0 1.2 6.7 1.6 2.2 1 1 1 2 2 2 0 HOOK protein Nsp1_C PF05064.8 EGC33005.1 - 2.3 7.8 12.8 0.34 10.5 2.1 2.7 2 0 0 2 2 2 0 Nsp1-like C-terminal region DUF4164 PF13747.1 EGC33005.1 - 3.6 7.7 8.1 1.1 9.4 1.2 2.8 3 0 0 3 3 3 0 Domain of unknown function (DUF4164) DUF2959 PF11172.3 EGC33005.1 - 4.3 7.0 13.1 2 8.1 0.6 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) DUF745 PF05335.8 EGC33005.1 - 4.4 6.7 10.6 3.5 7.1 1.6 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF745) APG17 PF04108.7 EGC33005.1 - 4.7 5.9 17.0 0.54 8.9 3.9 2.7 1 1 1 3 3 3 0 Autophagy protein Apg17 FliD_N PF02465.13 EGC33005.1 - 6.8 7.1 10.7 2.4 8.6 3.1 2.9 2 1 1 3 3 3 0 Flagellar hook-associated protein 2 N-terminus Snapin_Pallidin PF14712.1 EGC33005.1 - 7.4 6.9 17.0 0.38 11.0 1.2 4.1 2 2 1 4 4 4 0 Snapin/Pallidin DUF2203 PF09969.4 EGC33005.1 - 9.4 6.4 7.7 1.6 8.9 0.7 2.6 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) zf-CCCH_2 PF14608.1 EGC33006.1 - 5.1e-19 67.4 74.8 1.4e-07 31.2 3.4 7.3 7 0 0 7 7 7 6 Zinc finger C-x8-C-x5-C-x3-H type PWI PF01480.12 EGC33006.1 - 1.9e-05 24.6 0.1 3.8e-05 23.7 0.1 1.4 1 0 0 1 1 1 1 PWI domain Sigma_reg_C PF13791.1 EGC33006.1 - 1.4 8.9 9.1 3 7.8 6.3 1.5 1 0 0 1 1 1 0 Sigma factor regulator C-terminal BRCT PF00533.21 EGC33007.1 - 2e-09 37.4 0.4 2e-09 37.4 0.3 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain Cpn60_TCP1 PF00118.19 EGC33008.1 - 8.9e-145 483.0 18.5 1e-144 482.8 12.8 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Arm PF00514.18 EGC33011.1 - 5.2e-52 172.0 6.6 5.9e-12 44.9 0.0 8.1 8 0 0 8 8 8 6 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC33011.1 - 4.2e-19 68.6 0.0 1.1e-09 38.3 0.0 4.6 1 1 4 5 5 5 3 HEAT repeats HEAT_EZ PF13513.1 EGC33011.1 - 2e-16 59.9 0.0 6.4e-07 29.6 0.0 4.9 3 2 2 5 5 5 4 HEAT-like repeat HEAT PF02985.17 EGC33011.1 - 5.7e-16 57.0 0.0 0.00013 21.7 0.0 5.4 5 0 0 5 5 5 3 HEAT repeat RICTOR_V PF14668.1 EGC33011.1 - 1.7e-06 27.8 2.4 0.36 10.7 0.1 4.2 3 2 2 5 5 5 2 Rapamycin-insensitive companion of mTOR, domain 5 Proteasom_PSMB PF10508.4 EGC33011.1 - 9e-06 24.2 0.2 0.019 13.2 0.0 2.5 2 1 0 2 2 2 2 Proteasome non-ATPase 26S subunit Arm_2 PF04826.8 EGC33011.1 - 2.2e-05 23.7 0.2 0.14 11.2 0.0 2.3 2 0 0 2 2 2 2 Armadillo-like Adaptin_N PF01602.15 EGC33011.1 - 3.4e-05 22.3 0.1 0.00093 17.6 0.0 2.2 1 1 1 2 2 2 2 Adaptin N terminal region KAP PF05804.7 EGC33011.1 - 0.0051 14.8 0.1 0.016 13.1 0.0 1.7 2 0 0 2 2 2 1 Kinesin-associated protein (KAP) CTNNBL PF08216.6 EGC33011.1 - 0.058 12.9 3.0 15 5.1 0.0 4.1 5 0 0 5 5 5 0 Catenin-beta-like, Arm-motif containing nuclear HEAT_PBS PF03130.11 EGC33011.1 - 0.23 12.0 2.4 53 4.7 0.1 3.9 4 1 0 4 4 4 0 PBS lyase HEAT-like repeat RNB PF00773.14 EGC33012.1 - 9.9e-98 327.3 0.0 9.9e-98 327.3 0.0 2.4 2 0 0 2 2 2 1 RNB domain PIN_4 PF13638.1 EGC33012.1 - 3.4e-17 62.8 2.1 3.4e-17 62.8 1.4 2.8 2 0 0 2 2 2 1 PIN domain Isochorismatase PF00857.15 EGC33013.1 - 3e-35 121.6 0.0 3.8e-35 121.3 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family IBR PF01485.16 EGC33014.1 - 1.1e-20 73.1 45.3 2.2e-11 43.4 6.8 4.9 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGC33014.1 - 1.9e-06 27.5 5.4 1.9e-06 27.5 3.7 4.2 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC33014.1 - 4.1e-05 23.5 8.4 4.1e-05 23.5 5.8 5.2 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC33014.1 - 0.0016 18.0 39.5 0.0053 16.3 4.4 4.3 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC33014.1 - 0.0025 17.4 7.4 0.0025 17.4 5.2 4.6 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF4214 PF13946.1 EGC33014.1 - 0.026 14.2 0.1 0.063 12.9 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4214) TIG PF01833.19 EGC33015.1 - 2.8e-08 33.6 17.3 1.9e-05 24.5 0.5 5.4 4 0 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.8 EGC33015.1 - 0.0022 18.1 15.3 0.0065 16.6 10.6 1.9 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.5 EGC33015.1 - 0.45 9.8 3.7 1.1 8.5 2.6 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain FNIP PF05725.7 EGC33016.1 - 1.1e-57 191.7 54.7 2.6e-11 43.2 2.5 8.3 4 2 5 9 9 9 9 FNIP Repeat LRR_5 PF13306.1 EGC33016.1 - 0.29 10.8 13.3 0.16 11.6 0.2 3.7 2 2 1 3 3 3 0 Leucine rich repeats (6 copies) DUF4071 PF13281.1 EGC33018.1 - 0.15 10.9 13.6 0.17 10.6 9.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4071) Mut7-C PF01927.11 EGC33018.1 - 0.58 10.1 7.9 0.68 9.8 5.5 1.1 1 0 0 1 1 1 0 Mut7-C RNAse domain ING PF12998.2 EGC33018.1 - 0.91 9.8 27.0 1.5 9.1 18.5 1.5 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding Rtf2 PF04641.7 EGC33018.1 - 1.6 7.8 16.9 1.8 7.7 11.7 1.0 1 0 0 1 1 1 0 Rtf2 RING-finger HAUS6_N PF14661.1 EGC33018.1 - 1.9 7.7 21.7 2.1 7.6 15.0 1.0 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF148 PF02520.12 EGC33018.1 - 3.2 7.5 31.5 9 6.1 21.8 1.6 1 1 0 1 1 1 0 Domain of unknown function DUF148 DUF1107 PF06526.7 EGC33018.1 - 3.4 7.5 7.0 2.2 8.1 1.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1107) DUF724 PF05266.9 EGC33018.1 - 7.1 6.2 25.7 9.3 5.8 17.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) SKG6 PF08693.5 EGC33019.1 - 0.038 13.3 7.2 0.11 11.8 5.0 1.8 1 0 0 1 1 1 0 Transmembrane alpha-helix domain EGF_2 PF07974.8 EGC33019.1 - 0.45 10.7 4.3 1.3 9.2 3.0 1.8 1 0 0 1 1 1 0 EGF-like domain ABC2_membrane PF01061.19 EGC33020.1 - 4.4e-36 124.0 23.6 4.4e-36 124.0 16.4 1.5 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC33020.1 - 6.6e-26 91.2 0.1 1.4e-25 90.2 0.0 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC33020.1 - 1.1e-08 35.4 8.9 1e-06 28.9 0.0 3.6 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGC33020.1 - 6.7e-05 22.3 0.1 0.00016 21.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC33020.1 - 8.2e-05 22.7 0.0 0.0072 16.4 0.1 2.9 2 1 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC33020.1 - 9.6e-05 21.6 0.1 0.00019 20.6 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC33020.1 - 0.00028 20.3 0.0 0.0011 18.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC33020.1 - 0.00083 19.3 0.0 0.0013 18.7 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGC33020.1 - 0.0018 19.0 0.1 0.005 17.6 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC33020.1 - 0.0042 17.3 1.7 0.0052 17.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain SMC_N PF02463.14 EGC33020.1 - 0.011 15.0 6.4 0.13 11.4 0.0 3.0 1 1 1 2 2 2 0 RecF/RecN/SMC N terminal domain Arch_ATPase PF01637.13 EGC33020.1 - 0.016 14.8 0.3 0.016 14.8 0.2 1.7 2 0 0 2 2 1 0 Archaeal ATPase AAA_10 PF12846.2 EGC33020.1 - 0.041 13.3 0.0 0.072 12.5 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EGC33020.1 - 0.056 13.3 0.0 0.11 12.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGC33020.1 - 0.057 13.3 0.2 0.39 10.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EGC33020.1 - 0.098 12.3 0.1 0.24 11.0 0.1 1.7 1 0 0 1 1 1 0 NACHT domain AAA_28 PF13521.1 EGC33020.1 - 0.11 12.5 0.1 0.19 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGC33020.1 - 0.24 11.7 0.1 0.24 11.7 0.1 2.5 2 1 1 3 3 2 0 AAA domain ABC2_membrane_3 PF12698.2 EGC33020.1 - 4.6 6.1 36.7 0.054 12.5 18.0 2.5 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EGC33021.1 - 7.9e-35 119.9 25.0 7.9e-35 119.9 17.3 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC33021.1 - 1.9e-25 89.7 0.0 3.3e-25 88.9 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC33021.1 - 2.4e-09 37.5 0.0 2.9e-07 30.7 0.0 2.5 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC33021.1 - 3.5e-05 23.9 0.0 0.0035 17.4 0.1 3.0 2 1 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC33021.1 - 6.8e-05 22.0 0.2 0.19 10.7 0.6 2.5 2 1 0 2 2 2 2 AAA ATPase domain AAA_29 PF13555.1 EGC33021.1 - 7e-05 22.2 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC33021.1 - 0.0001 21.8 0.0 0.0024 17.3 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC33021.1 - 0.00031 19.9 0.0 0.00065 18.9 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGC33021.1 - 0.001 19.0 0.0 0.0017 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_17 PF13207.1 EGC33021.1 - 0.0018 19.0 0.4 0.005 17.6 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_18 PF13238.1 EGC33021.1 - 0.0021 18.3 0.0 0.005 17.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGC33021.1 - 0.0041 16.3 0.0 0.11 11.7 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_10 PF12846.2 EGC33021.1 - 0.028 13.8 0.0 0.061 12.7 0.0 1.5 2 0 0 2 2 1 0 AAA-like domain Arch_ATPase PF01637.13 EGC33021.1 - 0.032 13.9 0.2 0.057 13.1 0.1 1.4 1 0 0 1 1 1 0 Archaeal ATPase AAA_33 PF13671.1 EGC33021.1 - 0.047 13.5 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGC33021.1 - 0.063 13.2 0.1 0.39 10.6 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EGC33021.1 - 0.073 13.0 0.1 0.17 11.8 0.1 1.6 1 0 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGC33021.1 - 0.089 12.7 0.0 0.2 11.6 0.0 1.6 1 0 0 1 1 1 0 50S ribosome-binding GTPase NACHT PF05729.7 EGC33021.1 - 0.11 12.1 0.5 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_23 PF13476.1 EGC33021.1 - 0.12 12.6 0.0 0.12 12.6 0.0 2.4 1 1 1 2 2 2 0 AAA domain PDR_CDR PF06422.7 EGC33021.1 - 0.15 11.7 0.1 0.15 11.7 0.1 2.8 3 0 0 3 3 2 0 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGC33021.1 - 0.16 10.9 26.7 0.034 13.1 14.9 2.0 1 1 1 2 2 2 0 ABC-2 family transporter protein Peptidase_M18 PF02127.10 EGC33023.1 - 6.1e-157 522.5 0.0 6.9e-157 522.3 0.0 1.0 1 0 0 1 1 1 1 Aminopeptidase I zinc metalloprotease (M18) Peptidase_M42 PF05343.9 EGC33023.1 - 4.2e-06 25.7 0.0 2.3e-05 23.3 0.0 2.0 1 1 1 2 2 2 1 M42 glutamyl aminopeptidase Actin PF00022.14 EGC33024.1 - 2.3e-70 237.0 0.0 3.6e-70 236.3 0.0 1.2 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC33024.1 - 0.11 11.1 0.0 3.4 6.1 0.0 2.6 2 1 0 2 2 2 0 MreB/Mbl protein FAD-oxidase_C PF02913.14 EGC33025.1 - 3.6e-55 186.9 0.0 5.8e-55 186.3 0.0 1.3 1 0 0 1 1 1 1 FAD linked oxidases, C-terminal domain FAD_binding_4 PF01565.18 EGC33025.1 - 5.2e-38 129.6 0.0 9.4e-38 128.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain PhoU PF01895.14 EGC33026.1 - 0.097 13.1 3.0 0.76 10.2 0.0 2.5 1 1 1 2 2 2 0 PhoU domain PhoU PF01895.14 EGC33027.1 - 0.021 15.2 0.9 0.11 12.8 0.0 2.5 1 1 1 2 2 2 0 PhoU domain POX PF07526.6 EGC33030.1 - 0.34 11.1 3.5 1 9.5 2.4 2.2 1 1 0 1 1 1 0 Associated with HOX Apc15p PF05841.6 EGC33030.1 - 1.2 9.8 12.9 1.2 9.8 5.5 2.4 2 0 0 2 2 2 0 Apc15p protein Sugar_tr PF00083.19 EGC33031.1 - 1.5e-96 323.7 38.7 2e-96 323.3 26.8 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGC33031.1 - 3.8e-45 154.1 60.5 7.7e-35 120.2 24.4 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGC33031.1 - 0.0032 15.6 12.1 0.022 12.9 1.2 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector Prefoldin_2 PF01920.15 EGC33032.1 - 2.5e-17 62.5 14.5 2.5e-17 62.5 10.0 1.7 1 1 1 2 2 2 1 Prefoldin subunit Prefoldin_3 PF13758.1 EGC33032.1 - 0.0011 18.6 6.7 0.0016 18.1 4.7 1.3 1 0 0 1 1 1 1 Prefoldin subunit COG2 PF06148.6 EGC33032.1 - 0.038 13.8 4.1 3 7.7 1.0 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 CDC37_N PF03234.9 EGC33032.1 - 0.11 12.7 8.6 0.14 12.4 5.9 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Rotamase PF00639.16 EGC33032.1 - 0.12 13.1 0.6 0.12 13.1 0.4 2.2 1 1 1 2 2 2 0 PPIC-type PPIASE domain Mnd1 PF03962.10 EGC33032.1 - 0.15 11.7 12.5 0.34 10.5 8.6 1.5 1 1 1 2 2 2 0 Mnd1 family Atg31 PF09795.4 EGC33032.1 - 0.15 11.7 6.5 0.19 11.4 4.5 1.1 1 0 0 1 1 1 0 Autophagy-related protein 31 YlqD PF11068.3 EGC33032.1 - 0.17 11.9 14.9 0.53 10.3 3.2 2.1 2 0 0 2 2 2 0 YlqD protein IncA PF04156.9 EGC33032.1 - 0.18 11.3 14.6 0.34 10.4 4.4 2.0 1 1 1 2 2 2 0 IncA protein DUF641 PF04859.7 EGC33032.1 - 0.2 11.4 8.2 0.13 12.0 2.0 2.0 2 0 0 2 2 2 0 Plant protein of unknown function (DUF641) Macoilin PF09726.4 EGC33032.1 - 0.21 9.8 9.6 0.26 9.5 6.7 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF3452 PF11934.3 EGC33032.1 - 0.23 10.7 3.4 0.31 10.3 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3452) DUF4164 PF13747.1 EGC33032.1 - 0.28 11.3 9.9 0.73 9.9 2.4 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) DUF1515 PF07439.6 EGC33032.1 - 0.34 10.7 2.4 6.1 6.6 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1515) Nsp1_C PF05064.8 EGC33032.1 - 0.51 9.9 14.7 1.9 8.1 4.0 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region Cob_adeno_trans PF01923.13 EGC33032.1 - 0.62 9.8 5.0 0.32 10.7 0.7 1.9 1 1 1 2 2 2 0 Cobalamin adenosyltransferase RNA_pol_Rpb1_7 PF04990.7 EGC33032.1 - 0.81 9.4 5.0 1.1 8.9 3.5 1.3 1 0 0 1 1 1 0 RNA polymerase Rpb1, domain 7 TMF_TATA_bd PF12325.3 EGC33032.1 - 0.97 9.1 11.8 0.12 12.1 2.9 2.1 2 0 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Nup54 PF13874.1 EGC33032.1 - 0.98 9.0 12.5 0.99 9.0 3.0 2.1 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DMPK_coil PF08826.5 EGC33032.1 - 1.2 9.0 15.6 1.5 8.7 1.5 2.3 2 0 0 2 2 2 0 DMPK coiled coil domain like BRE1 PF08647.6 EGC33032.1 - 1.2 9.0 12.7 1.2 9.1 2.4 2.7 2 2 0 2 2 2 0 BRE1 E3 ubiquitin ligase Fib_alpha PF08702.5 EGC33032.1 - 1.3 9.1 12.8 0.72 9.9 0.9 2.3 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family Cep57_CLD_2 PF14197.1 EGC33032.1 - 1.4 8.9 8.4 0.15 12.0 2.2 2.1 2 1 1 3 3 3 0 Centrosome localisation domain of PPC89 DUF1664 PF07889.7 EGC33032.1 - 1.9 8.3 7.3 6.9 6.4 0.9 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) Allexi_40kDa PF05549.6 EGC33032.1 - 1.9 7.7 7.5 6 6.0 3.0 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein Prefoldin PF02996.12 EGC33032.1 - 2.7 7.6 14.8 28 4.4 10.2 2.5 1 1 0 1 1 1 0 Prefoldin subunit NPV_P10 PF05531.7 EGC33032.1 - 2.9 8.2 11.2 2.4 8.4 1.8 2.4 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein Occludin_ELL PF07303.8 EGC33032.1 - 7.2 7.4 11.8 12 6.7 2.6 2.1 1 1 1 2 2 2 0 Occludin homology domain DASH_Dad3 PF08656.5 EGC33032.1 - 7.6 6.3 9.7 6.1 6.6 2.6 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad3 Homeobox_KN PF05920.6 EGC33033.1 - 0.00052 19.6 0.6 0.002 17.7 0.2 2.2 2 0 0 2 2 2 1 Homeobox KN domain Homeobox PF00046.24 EGC33033.1 - 0.029 14.0 1.1 0.077 12.6 0.8 1.8 1 0 0 1 1 1 0 Homeobox domain TMEM154 PF15102.1 EGC33033.1 - 0.23 11.1 3.6 0.64 9.7 2.5 1.8 1 0 0 1 1 1 0 TMEM154 protein family Tir_receptor_C PF07489.6 EGC33033.1 - 5.1 6.7 8.2 9.5 5.8 5.7 1.4 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus PDEase_II PF02112.10 EGC33034.1 - 7.5e-127 422.8 0.0 9.6e-127 422.5 0.0 1.0 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGC33034.1 - 0.0095 15.4 0.4 0.059 12.9 0.1 2.2 1 1 1 2 2 2 1 Beta-lactamase superfamily domain UPF0118 PF01594.11 EGC33035.1 - 1.1 8.1 4.9 0.56 9.1 1.8 1.6 2 0 0 2 2 2 0 Domain of unknown function DUF20 RNase_T PF00929.19 EGC33039.1 - 1.9e-05 24.9 0.1 0.00011 22.5 0.1 1.9 1 1 1 2 2 2 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGC33039.1 - 0.0017 17.8 0.0 0.0021 17.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease RNase_H_2 PF13482.1 EGC33039.1 - 0.0035 17.1 0.0 0.0042 16.9 0.0 1.2 1 0 0 1 1 1 1 RNase_H superfamily DUF2238 PF09997.4 EGC33040.1 - 0.11 11.8 0.5 0.16 11.3 0.4 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2238) Lin-8 PF03353.10 EGC33040.1 - 0.13 11.5 6.6 1.2 8.3 0.9 2.1 2 0 0 2 2 2 0 Ras-mediated vulval-induction antagonist DUF605 PF04652.11 EGC33041.1 - 0.00039 19.9 23.9 0.0004 19.9 16.6 1.1 1 0 0 1 1 1 1 Vta1 like GET2 PF08690.5 EGC33041.1 - 0.017 14.3 0.0 0.025 13.8 0.0 1.2 1 0 0 1 1 1 0 GET complex subunit GET2 Kei1 PF08552.6 EGC33041.1 - 0.087 12.4 0.0 0.09 12.4 0.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF2296 PF10058.4 EGC33041.1 - 0.09 12.5 0.2 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Predicted integral membrane metal-binding protein (DUF2296) Suf PF05843.9 EGC33041.1 - 1.1 8.9 14.2 1.4 8.5 9.9 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) DUF2413 PF10310.4 EGC33041.1 - 1.8 7.2 8.6 2.3 6.9 6.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) PHD_3 PF13922.1 EGC33041.1 - 4.4 7.6 8.2 12 6.2 5.7 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx MAS20 PF02064.10 EGC33041.1 - 5.3 6.9 8.3 2 8.3 0.3 2.2 2 0 0 2 2 2 0 MAS20 protein import receptor Spt20 PF12090.3 EGC33041.1 - 6.4 6.0 16.9 1.4 8.2 9.4 1.7 2 1 0 2 2 2 0 Spt20 family DUF4175 PF13779.1 EGC33041.1 - 7.9 4.0 18.2 9 3.8 12.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Pro_dh PF01619.13 EGC33044.1 - 5.2e-59 199.7 0.3 9e-59 198.9 0.2 1.3 1 0 0 1 1 1 1 Proline dehydrogenase DEAD PF00270.24 EGC33045.1 - 1.3e-47 161.4 0.0 1.6e-46 157.8 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC33045.1 - 3.5e-24 84.4 0.0 6.2e-23 80.4 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGC33045.1 - 0.00023 20.0 0.0 0.00091 18.1 0.0 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain SecA_DEAD PF07517.9 EGC33045.1 - 0.051 12.8 0.0 0.071 12.3 0.0 1.4 1 0 0 1 1 1 0 SecA DEAD-like domain Zot PF05707.7 EGC33045.1 - 0.13 11.7 0.2 0.81 9.1 0.1 2.4 2 1 0 2 2 2 0 Zonular occludens toxin (Zot) PH PF00169.24 EGC33047.1 - 7.1e-10 39.0 1.3 2e-09 37.5 0.1 2.4 3 0 0 3 3 3 1 PH domain HA2 PF04408.18 EGC33048.1 - 2.2e-26 91.8 0.1 5.1e-26 90.6 0.1 1.7 1 0 0 1 1 1 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGC33048.1 - 3e-24 85.0 0.0 7.4e-24 83.7 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGC33048.1 - 7.7e-11 41.7 0.0 2e-10 40.3 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC33048.1 - 5.5e-08 32.4 0.0 1.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase AAA_22 PF13401.1 EGC33048.1 - 9.2e-05 22.5 0.3 0.0005 20.2 0.2 2.2 1 1 0 1 1 1 1 AAA domain ResIII PF04851.10 EGC33048.1 - 9.8e-05 22.2 0.1 0.093 12.5 0.0 2.8 2 1 0 2 2 2 2 Type III restriction enzyme, res subunit DUF2075 PF09848.4 EGC33048.1 - 0.0054 15.7 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) PhoH PF02562.11 EGC33048.1 - 0.0081 15.4 0.4 0.035 13.3 0.0 2.2 3 0 0 3 3 3 1 PhoH-like protein ABC_tran PF00005.22 EGC33048.1 - 0.0089 16.3 0.0 0.058 13.6 0.0 2.3 2 0 0 2 2 2 1 ABC transporter T2SE PF00437.15 EGC33048.1 - 0.0097 14.8 0.0 0.021 13.7 0.0 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_19 PF13245.1 EGC33048.1 - 0.016 14.9 0.1 0.06 13.1 0.0 1.9 2 0 0 2 2 2 0 Part of AAA domain UPF0079 PF02367.12 EGC33048.1 - 0.022 14.3 0.0 0.063 12.9 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EGC33048.1 - 0.026 14.0 0.0 0.05 13.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGC33048.1 - 0.028 13.5 0.3 0.14 11.2 0.0 2.1 1 1 1 2 2 2 0 Zeta toxin IstB_IS21 PF01695.12 EGC33048.1 - 0.035 13.5 0.1 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_29 PF13555.1 EGC33048.1 - 0.036 13.5 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain Flavi_DEAD PF07652.9 EGC33048.1 - 0.044 13.5 0.0 0.17 11.6 0.0 2.0 2 0 0 2 2 1 0 Flavivirus DEAD domain DUF258 PF03193.11 EGC33048.1 - 0.09 11.9 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC33048.1 - 0.12 12.2 0.0 0.3 10.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain FNIP PF05725.7 EGC33049.1 - 2.1e-16 59.5 0.0 4.7e-14 52.0 0.0 2.0 1 1 1 2 2 2 2 FNIP Repeat FNIP PF05725.7 EGC33050.1 - 8.3e-06 25.6 38.5 0.0029 17.5 0.5 9.7 6 3 3 9 9 9 5 FNIP Repeat Macoilin PF09726.4 EGC33051.1 - 2.3e-05 22.9 32.0 2.9e-05 22.5 22.2 1.1 1 0 0 1 1 1 1 Transmembrane protein F-box-like PF12937.2 EGC33052.1 - 2.5e-06 27.1 2.0 7.1e-06 25.6 0.4 2.3 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC33052.1 - 1.8e-05 24.2 0.5 1.8e-05 24.2 0.4 2.5 3 0 0 3 3 3 1 F-box domain SprA-related PF12118.3 EGC33052.1 - 0.95 8.7 29.8 1.5 8.0 20.7 1.3 1 0 0 1 1 1 0 SprA-related family FNIP PF05725.7 EGC33053.1 - 3.7e-17 61.9 3.5 7.4e-08 32.2 0.2 5.0 2 2 3 6 6 6 5 FNIP Repeat Tcp10_C PF07202.8 EGC33053.1 - 0.022 14.3 0.2 4 6.9 0.0 2.5 3 0 0 3 3 3 0 T-complex protein 10 C-terminus RPAP2_Rtr1 PF04181.8 EGC33054.1 - 6.3e-19 67.8 2.9 1.9e-18 66.3 2.0 1.9 1 0 0 1 1 1 1 Rtr1/RPAP2 family Topoisom_bac PF01131.15 EGC33055.1 - 1.3e-96 323.8 0.5 1.8e-96 323.4 0.3 1.2 1 0 0 1 1 1 1 DNA topoisomerase Toprim PF01751.17 EGC33055.1 - 2.3e-18 65.9 0.1 6.5e-18 64.5 0.1 1.8 1 0 0 1 1 1 1 Toprim domain HypA PF01155.14 EGC33055.1 - 0.24 11.0 10.4 1 9.0 1.5 2.9 1 1 1 2 2 2 0 Hydrogenase expression/synthesis hypA family Zn_ribbon_recom PF13408.1 EGC33055.1 - 0.51 10.6 0.0 0.51 10.6 0.0 2.8 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain zf-CHY PF05495.7 EGC33055.1 - 0.86 9.8 12.3 0.093 12.8 0.6 2.9 2 1 0 2 2 2 0 CHY zinc finger FYVE PF01363.16 EGC33055.1 - 9.3 6.2 14.0 2.4 8.1 1.4 3.1 3 1 0 3 3 3 0 FYVE zinc finger ketoacyl-synt PF00109.21 EGC33057.1 - 2.1e-62 210.8 0.0 3.3e-62 210.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC33057.1 - 2.5e-44 151.9 0.0 4.4e-44 151.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC33057.1 - 1.1e-30 105.9 0.0 3.7e-30 104.2 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC33057.1 - 2.6e-24 85.8 0.0 5.6e-24 84.7 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC33057.1 - 5.7e-22 78.2 0.0 9e-22 77.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EGC33057.1 - 1.3e-19 70.4 0.0 1.3e-19 70.4 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain adh_short PF00106.20 EGC33057.1 - 1.2e-15 57.8 0.0 2.1e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC33057.1 - 5.8e-08 32.6 0.0 1.5e-07 31.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC33057.1 - 1.2e-07 32.6 0.0 2.8e-07 31.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC33057.1 - 6.5e-07 29.0 0.0 1.5e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC33057.1 - 6.7e-07 29.7 0.0 4.7e-06 26.9 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC33057.1 - 2.5e-06 27.1 0.0 2.5e-06 27.1 0.0 5.3 5 0 0 5 5 5 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC33057.1 - 6.1e-06 26.7 0.0 0.00024 21.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EGC33057.1 - 1.8e-05 23.9 0.0 4.4e-05 22.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGC33057.1 - 0.015 15.5 0.1 0.042 14.1 0.1 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site Cpn60_TCP1 PF00118.19 EGC33058.1 - 4.3e-80 269.6 32.4 5.8e-76 256.0 21.3 2.0 2 0 0 2 2 2 2 TCP-1/cpn60 chaperonin family Pkinase PF00069.20 EGC33059.1 - 5.2e-66 222.4 0.0 7.5e-66 221.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33059.1 - 3.6e-39 134.3 0.0 5.4e-39 133.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PH_3 PF14593.1 EGC33059.1 - 3.6e-38 129.6 3.2 8.3e-38 128.4 2.2 1.6 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGC33059.1 - 2.5e-08 33.2 0.0 4.1e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC33059.1 - 0.0012 18.6 0.0 0.014 15.1 0.0 2.1 2 0 0 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC33059.1 - 0.0021 17.4 0.2 0.0055 16.0 0.0 1.6 2 0 0 2 2 2 1 RIO1 family Kdo PF06293.9 EGC33059.1 - 0.0035 16.4 0.0 0.0062 15.6 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Ribosomal_L29e PF01779.12 EGC33060.1 - 2.1e-16 59.4 13.8 3.3e-16 58.8 7.2 2.2 2 0 0 2 2 2 1 Ribosomal L29e protein family C2 PF00168.25 EGC33061.1 - 1.8e-17 62.9 0.1 3.2e-17 62.1 0.0 1.4 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 EGC33062.1 - 1.5e-15 56.8 0.2 4.2e-15 55.3 0.0 1.8 1 1 1 2 2 2 1 C2 domain Ank_2 PF12796.2 EGC33063.1 - 2.3e-05 24.6 1.0 0.0019 18.5 0.0 3.7 4 1 0 4 4 4 1 Ankyrin repeats (3 copies) Sdh_cyt PF01127.17 EGC33064.1 - 1.6e-19 69.8 0.3 2.1e-19 69.5 0.2 1.1 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit Sdh_cyt PF01127.17 EGC33066.1 - 4.7e-08 32.8 0.1 6.9e-08 32.3 0.0 1.2 1 0 0 1 1 1 1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit CUE PF02845.11 EGC33067.1 - 9.7e-15 53.7 0.8 5e-09 35.4 0.2 3.6 3 0 0 3 3 3 3 CUE domain UBA_4 PF14555.1 EGC33067.1 - 0.0016 17.8 0.0 1.9 8.0 0.0 2.6 2 0 0 2 2 2 2 UBA-like domain DUF605 PF04652.11 EGC33067.1 - 0.044 13.1 6.8 0.048 13.0 4.7 1.1 1 0 0 1 1 1 0 Vta1 like HSBP1 PF06825.7 EGC33067.1 - 0.19 11.3 2.9 0.52 9.9 0.0 3.0 4 0 0 4 4 4 0 Heat shock factor binding protein 1 OATP PF03137.15 EGC33068.1 - 0.46 8.4 5.4 0.37 8.7 0.5 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family V-ATPase_G PF03179.10 EGC33068.1 - 2 8.7 8.2 0.075 13.3 1.0 2.1 2 0 0 2 2 2 0 Vacuolar (H+)-ATPase G subunit Metallophos PF00149.23 EGC33070.1 - 1.3e-09 37.7 1.8 1.3e-09 37.7 1.2 2.2 2 1 1 3 3 3 1 Calcineurin-like phosphoesterase YMF19 PF02326.10 EGC33070.1 - 0.089 13.3 5.0 0.08 13.5 0.9 2.8 2 0 0 2 2 2 0 Plant ATP synthase F0 DUF3309 PF11752.3 EGC33070.1 - 0.12 12.1 5.7 0.34 10.7 4.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3309) DUF1673 PF07895.6 EGC33070.1 - 0.26 10.8 9.9 0.094 12.2 4.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) GRAB PF10375.4 EGC33071.1 - 0.019 14.6 2.9 1.2 8.9 0.0 3.2 2 0 0 2 2 2 0 GRIP-related Arf-binding domain SF3a60_bindingd PF12108.3 EGC33071.1 - 0.24 10.9 2.4 0.84 9.2 0.5 2.4 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain Oxidored_q3 PF00499.15 EGC33071.1 - 6.3 6.5 23.3 7.3 6.3 0.1 3.2 2 1 1 3 3 3 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Pkinase_Tyr PF07714.12 EGC33072.1 - 1.7e-50 171.5 0.0 2.1e-48 164.6 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGC33072.1 - 8.9e-45 152.8 0.0 2.2e-41 141.7 0.0 2.5 2 0 0 2 2 2 2 Protein kinase domain DEP PF00610.16 EGC33072.1 - 1.6e-31 107.8 0.8 4.5e-20 71.1 0.0 3.0 3 0 0 3 3 3 2 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) LRR_4 PF12799.2 EGC33072.1 - 4.2e-19 67.7 37.6 2.5e-08 33.3 1.2 6.0 6 0 0 6 6 6 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC33072.1 - 9.7e-15 54.0 30.8 1e-07 31.5 9.5 5.5 3 2 2 5 5 5 4 Leucine rich repeat LRR_1 PF00560.28 EGC33072.1 - 5.3e-11 40.9 32.4 0.0032 17.2 1.9 8.7 7 0 0 7 7 7 4 Leucine Rich Repeat Miro PF08477.8 EGC33072.1 - 5.6e-06 26.8 1.6 0.0092 16.4 0.0 3.7 4 0 0 4 4 4 2 Miro-like protein LRR_7 PF13504.1 EGC33072.1 - 0.00031 20.4 20.9 1.3 9.5 0.0 8.1 7 0 0 7 7 7 2 Leucine rich repeat Ras PF00071.17 EGC33072.1 - 0.00058 19.2 0.2 0.0025 17.2 0.0 2.1 2 0 0 2 2 2 1 Ras family LRR_6 PF13516.1 EGC33072.1 - 0.0092 15.9 26.9 0.081 13.0 0.5 7.9 7 0 0 7 7 7 2 Leucine Rich repeat DUF1404 PF07185.6 EGC33073.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1404) CytochromB561_N PF09786.4 EGC33073.1 - 0.098 11.0 7.1 0.13 10.7 4.9 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal HTH_23 PF13384.1 EGC33075.1 - 1.2e-06 27.9 0.2 2.3e-06 27.0 0.1 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGC33075.1 - 1.5e-05 24.8 0.5 2.4e-05 24.2 0.3 1.3 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EGC33075.1 - 2.7e-05 24.2 0.1 3.7e-05 23.8 0.0 1.2 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGC33075.1 - 8.3e-05 22.0 0.2 0.00016 21.1 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.13 EGC33075.1 - 0.018 14.7 0.0 0.034 13.8 0.0 1.5 1 0 0 1 1 1 0 'Paired box' domain TrmB PF01978.14 EGC33075.1 - 0.023 14.3 0.0 0.039 13.6 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Phage_pRha PF09669.5 EGC33075.1 - 0.032 14.6 0.1 0.043 14.1 0.1 1.2 1 0 0 1 1 1 0 Phage regulatory protein Rha (Phage_pRha) HTH_24 PF13412.1 EGC33075.1 - 0.033 13.5 0.1 0.073 12.4 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding DUF603 PF04645.7 EGC33075.1 - 0.036 14.0 0.0 0.044 13.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF603 Glyco_hydro_85 PF03644.8 EGC33075.1 - 0.062 12.4 0.1 0.089 11.8 0.1 1.3 1 1 0 1 1 1 0 Glycosyl hydrolase family 85 Fe_dep_repress PF01325.14 EGC33075.1 - 0.069 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4_2 PF08281.7 EGC33075.1 - 0.075 12.4 0.1 0.12 11.8 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 DUF2316 PF10078.4 EGC33075.1 - 0.081 12.9 0.6 0.89 9.5 0.4 2.2 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2316) HTH_AsnC-type PF13404.1 EGC33075.1 - 0.087 12.3 0.0 0.16 11.5 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain Rdx PF10262.4 EGC33076.1 - 0.067 13.2 0.0 0.25 11.4 0.0 2.0 1 0 0 1 1 1 0 Rdx family Cadherin-like PF12733.2 EGC33076.1 - 0.099 12.9 2.8 0.33 11.2 0.3 2.6 3 0 0 3 3 3 0 Cadherin-like beta sandwich domain Big_2 PF02368.13 EGC33076.1 - 0.14 12.0 8.1 3.7 7.5 0.2 3.7 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 2) EpsG PF14897.1 EGC33080.1 - 0.0001 21.3 13.4 0.004 16.1 2.7 2.1 2 0 0 2 2 2 2 EpsG family Cadherin-like PF12733.2 EGC33080.1 - 0.00086 19.5 4.0 2.5 8.4 0.2 4.2 4 0 0 4 4 4 2 Cadherin-like beta sandwich domain DUF2057 PF09829.4 EGC33080.1 - 0.0017 18.0 0.0 3.2 7.3 0.0 2.9 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2057) Med20 PF08612.6 EGC33080.1 - 0.0023 17.1 0.3 0.6 9.2 0.0 2.5 2 0 0 2 2 2 2 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF3598 PF12204.3 EGC33080.1 - 0.091 11.9 1.9 6.6 5.8 0.1 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF3598) DUF2970 PF11174.3 EGC33080.1 - 1.4 8.5 5.6 3.8 7.1 0.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2970) DDE_3 PF13358.1 EGC33081.1 - 1.9e-09 37.4 0.7 1.9e-09 37.4 0.5 1.9 2 0 0 2 2 2 1 DDE superfamily endonuclease FNIP PF05725.7 EGC33082.1 - 3e-57 190.3 48.4 1.2e-09 37.9 0.1 10.2 4 2 6 10 10 10 10 FNIP Repeat LRR_5 PF13306.1 EGC33082.1 - 0.045 13.4 5.3 0.17 11.6 0.2 3.5 3 1 0 3 3 3 0 Leucine rich repeats (6 copies) DUF1129 PF06570.6 EGC33083.1 - 0.0019 17.5 0.3 0.0019 17.5 0.2 3.6 3 1 0 4 4 4 1 Protein of unknown function (DUF1129) TMEM154 PF15102.1 EGC33083.1 - 0.0072 16.0 0.1 0.0072 16.0 0.1 4.9 5 2 2 7 7 7 1 TMEM154 protein family DUF2157 PF09925.4 EGC33083.1 - 0.51 9.9 12.6 4.8 6.7 1.4 3.8 3 1 0 3 3 3 0 Predicted membrane protein (DUF2157) WBP-1 PF11669.3 EGC33083.1 - 0.77 9.8 6.4 5.7 7.0 0.0 4.2 2 2 2 4 4 4 0 WW domain-binding protein 1 AA_permease_2 PF13520.1 EGC33083.1 - 0.9 8.0 41.7 0.33 9.4 8.4 3.6 2 2 1 3 3 3 0 Amino acid permease DUF373 PF04123.8 EGC33083.1 - 5.9 5.7 17.3 0.012 14.6 1.1 2.8 1 1 2 3 3 3 0 Domain of unknown function (DUF373) DUF805 PF05656.9 EGC33083.1 - 7.7 6.3 35.4 0.12 12.2 0.8 4.4 2 1 2 4 4 4 0 Protein of unknown function (DUF805) Phosducin PF02114.11 EGC33084.1 - 0.061 12.0 0.1 0.075 11.7 0.1 1.1 1 0 0 1 1 1 0 Phosducin Macoilin PF09726.4 EGC33085.1 - 1.1 7.4 7.0 1.2 7.3 4.9 1.0 1 0 0 1 1 1 0 Transmembrane protein PRA1 PF03208.14 EGC33086.1 - 0.041 13.2 3.7 0.087 12.1 2.6 1.5 1 1 0 1 1 1 0 PRA1 family protein EpsG PF14897.1 EGC33088.1 - 8.4e-05 21.6 7.1 0.01 14.7 0.4 2.1 2 0 0 2 2 2 2 EpsG family DUF2057 PF09829.4 EGC33088.1 - 0.0024 17.5 0.0 3.3 7.3 0.0 2.8 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2057) Cadherin-like PF12733.2 EGC33088.1 - 0.0025 18.0 1.4 7.8 6.8 0.0 4.1 4 0 0 4 4 4 2 Cadherin-like beta sandwich domain Med20 PF08612.6 EGC33088.1 - 0.025 13.7 0.8 0.51 9.4 0.0 2.6 3 0 0 3 3 3 0 TATA-binding related factor (TRF) of subunit 20 of Mediator complex RSD-2 PF07547.8 EGC33088.1 - 0.034 14.2 0.1 16 5.7 0.0 2.7 2 0 0 2 2 2 0 RSD-2 N-terminal domain Sas10_Utp3 PF04000.10 EGC33089.1 - 1e-20 73.6 0.6 1e-20 73.6 0.4 3.7 4 1 0 4 4 4 1 Sas10/Utp3/C1D family Sas10 PF09368.5 EGC33089.1 - 6.7e-16 58.2 12.0 6.7e-16 58.2 8.3 3.5 4 0 0 4 4 4 1 Sas10 C-terminal domain zf-AN1 PF01428.11 EGC33091.1 - 7.6e-22 76.9 27.2 5.1e-12 45.4 6.4 3.5 2 2 2 4 4 4 3 AN1-like Zinc finger Transp_Tc5_C PF04236.10 EGC33091.1 - 0.0012 18.9 4.2 0.0012 18.9 2.9 2.9 3 1 1 4 4 4 2 Tc5 transposase C-terminal domain DUF1272 PF06906.6 EGC33091.1 - 0.0028 17.4 3.3 0.0028 17.4 2.3 3.5 3 1 1 4 4 4 1 Protein of unknown function (DUF1272) PolC_DP2 PF03833.8 EGC33091.1 - 0.033 11.8 1.3 0.038 11.6 0.9 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 zf-FCS PF06467.9 EGC33091.1 - 1 9.0 19.1 0.73 9.5 1.7 4.2 4 0 0 4 4 4 0 MYM-type Zinc finger with FCS sequence motif DUF3808 PF10300.4 EGC33092.1 - 1.5e-43 149.0 7.8 3.5e-43 147.8 5.3 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_11 PF13414.1 EGC33092.1 - 6.7e-11 41.6 6.5 0.0029 17.2 0.0 4.8 4 1 0 4 4 4 3 TPR repeat TPR_12 PF13424.1 EGC33092.1 - 6.9e-11 41.9 7.7 1.3e-05 25.0 0.9 4.7 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC33092.1 - 3.8e-08 33.7 0.0 0.018 15.6 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC33092.1 - 4.9e-08 33.1 0.7 0.0061 16.8 0.0 4.2 4 1 0 4 4 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC33092.1 - 2e-07 30.3 11.0 0.11 12.4 0.6 6.7 7 0 0 7 7 7 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC33092.1 - 1.7e-05 24.8 11.7 0.00033 20.7 0.8 4.5 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_6 PF13174.1 EGC33092.1 - 1.7e-05 24.9 7.7 0.042 14.3 0.0 6.0 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_21 PF09976.4 EGC33092.1 - 4.7e-05 23.3 0.9 0.022 14.6 0.0 3.7 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC33092.1 - 0.0004 19.8 11.0 1.4 8.6 0.1 5.2 5 0 0 5 5 5 2 Tetratricopeptide repeat RPN7 PF10602.4 EGC33092.1 - 0.00062 19.1 0.6 0.00062 19.1 0.4 3.1 3 1 0 3 3 3 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EGC33092.1 - 0.011 16.3 0.0 4.1 8.2 0.0 4.3 4 2 1 5 5 4 0 Tetratricopeptide repeat TPR_20 PF14561.1 EGC33092.1 - 0.044 13.9 0.1 3.8 7.6 0.1 2.9 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC33092.1 - 0.068 12.9 19.6 9.5 6.2 1.8 6.1 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC33092.1 - 0.1 12.5 0.2 20 5.3 0.1 3.9 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC33092.1 - 0.1 12.8 1.6 38 4.8 0.1 4.5 4 0 0 4 4 4 0 Tetratricopeptide repeat EGF_2 PF07974.8 EGC33093.1 - 0.14 12.3 13.7 0.092 12.9 8.0 1.9 2 0 0 2 2 2 0 EGF-like domain DUF4140 PF13600.1 EGC33094.1 - 4.1 7.9 9.7 1.4 9.4 0.8 3.7 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Glyco_hydro_31 PF01055.21 EGC33095.1 - 6.1e-152 506.4 7.7 8.7e-152 505.9 5.3 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 31 Gal_mutarotas_2 PF13802.1 EGC33095.1 - 3e-22 78.2 0.5 1.5e-21 75.9 0.0 2.5 2 0 0 2 2 2 1 Galactose mutarotase-like Inhibitor_I67 PF11405.3 EGC33096.1 - 0.11 12.6 0.4 0.11 12.6 0.3 2.1 2 0 0 2 2 2 0 Bromelain inhibitor VI Kdo PF06293.9 EGC33097.1 - 0.033 13.2 0.1 0.051 12.6 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.9 EGC33097.1 - 0.038 12.0 0.0 0.044 11.8 0.0 1.0 1 0 0 1 1 1 0 CDC45-like protein ACI44 PF15270.1 EGC33097.1 - 0.047 13.6 5.5 0.24 11.3 0.3 2.6 2 1 1 3 3 3 0 Metallo-carboxypeptidase inhibitor Nodulin_late PF07127.6 EGC33097.1 - 0.11 12.6 5.4 0.85 9.7 0.2 2.2 2 0 0 2 2 2 0 Late nodulin protein WAP PF00095.16 EGC33097.1 - 0.16 11.9 2.7 6.3 6.8 0.3 2.3 2 0 0 2 2 2 0 WAP-type (Whey Acidic Protein) 'four-disulfide core' CLIP PF12032.3 EGC33098.1 - 0.0056 16.7 2.7 0.089 12.8 0.2 2.3 1 1 1 2 2 2 2 Regulatory CLIP domain of proteinases LsmAD PF06741.8 EGC33099.1 - 5.7e-23 80.8 4.8 5.7e-23 80.8 3.3 2.6 2 0 0 2 2 2 1 LsmAD domain SM-ATX PF14438.1 EGC33099.1 - 1.2e-18 66.8 2.4 1.4e-18 66.5 0.0 2.5 2 0 0 2 2 2 1 Ataxin 2 SM domain PAM2 PF07145.10 EGC33099.1 - 6.8e-06 25.2 1.4 2.2e-05 23.6 0.6 2.3 2 0 0 2 2 2 1 Ataxin-2 C-terminal region CobT PF06213.7 EGC33099.1 - 0.56 9.2 8.1 1.2 8.1 5.6 1.4 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT TRAP_alpha PF03896.11 EGC33099.1 - 1.4 7.8 8.9 2.5 7.0 6.2 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit RP-C_C PF11800.3 EGC33099.1 - 2.1 7.9 11.5 11 5.7 4.7 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region BBS2_Mid PF14783.1 EGC33100.1 - 8.6e-10 38.3 1.1 0.002 17.8 0.0 3.5 2 1 1 3 3 3 3 Ciliary BBSome complex subunit 2, middle region FG-GAP PF01839.18 EGC33100.1 - 8.8e-09 34.8 1.0 0.00094 18.8 0.0 2.6 2 0 0 2 2 2 2 FG-GAP repeat Trypan_PARP PF05887.6 EGC33101.1 - 1.9e-08 34.2 139.5 2e-05 24.4 46.8 5.7 2 1 4 6 6 6 4 Procyclic acidic repetitive protein (PARP) YqzL PF14006.1 EGC33101.1 - 0.063 13.4 1.7 1 9.6 0.0 3.1 2 0 0 2 2 2 0 YqzL-like protein DUF2798 PF11391.3 EGC33102.1 - 6.1e-06 25.8 33.5 0.63 9.8 0.1 6.4 3 2 4 7 7 7 5 Protein of unknown function (DUF2798) EpsG PF14897.1 EGC33102.1 - 0.0034 16.3 12.9 0.26 10.2 0.1 3.5 3 1 0 3 3 3 2 EpsG family DUF2456 PF10445.4 EGC33102.1 - 0.0047 16.8 17.5 4.6 7.2 0.1 5.9 4 1 0 6 6 6 2 Protein of unknown function (DUF2456) DUF4231 PF14015.1 EGC33102.1 - 0.72 9.8 32.1 0.79 9.7 2.8 5.7 1 1 2 3 3 3 0 Protein of unknown function (DUF4231) Colicin_V PF02674.11 EGC33102.1 - 0.77 9.5 25.8 3.1 7.6 2.1 4.5 1 1 3 4 4 4 0 Colicin V production protein MRP-L51 PF10244.4 EGC33102.1 - 1.1 9.2 9.0 72 3.5 0.0 4.9 5 0 0 5 5 5 0 Mitochondrial ribosomal subunit PGG PF13962.1 EGC33102.1 - 1.2 8.8 21.5 3.9 7.1 0.1 5.0 2 2 4 6 6 6 0 Domain of unknown function NS3_envE PF02723.9 EGC33102.1 - 2.6 8.0 14.4 1.1e+02 2.8 0.1 5.9 6 0 0 6 6 6 0 Non-structural protein NS3/Small envelope protein E zf-DHHC PF01529.15 EGC33102.1 - 6.5 6.1 20.1 9.7 5.5 3.9 3.7 1 1 1 2 2 2 0 DHHC palmitoyltransferase L6_membrane PF05805.7 EGC33102.1 - 9.5 5.7 32.0 0.23 11.0 1.2 5.5 2 2 2 5 5 5 0 L6 membrane protein Fucokinase PF07959.7 EGC33103.1 - 1.5e-37 129.1 0.0 2.1e-37 128.6 0.0 1.2 1 0 0 1 1 1 1 L-fucokinase GHMP_kinases_N PF00288.21 EGC33103.1 - 2.5e-07 30.6 0.1 5.8e-07 29.4 0.1 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGC33103.1 - 0.0025 17.9 0.0 0.0061 16.7 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Syntaxin-6_N PF09177.6 EGC33104.1 - 0.18 12.2 5.2 0.24 11.8 3.6 1.3 1 1 0 1 1 1 0 Syntaxin 6, N-terminal EMP24_GP25L PF01105.19 EGC33104.1 - 0.18 11.4 4.3 0.22 11.2 3.0 1.3 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD DUF4065 PF13274.1 EGC33104.1 - 9.6 6.9 9.2 2.5 8.8 3.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4065) Sen15 PF09631.5 EGC33106.1 - 1.6e-18 66.7 0.8 2.3e-18 66.2 0.2 1.4 2 0 0 2 2 2 1 Sen15 protein Pex14_N PF04695.8 EGC33107.1 - 0.07 13.1 5.4 0.092 12.7 3.8 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region C2 PF00168.25 EGC33108.1 - 5.9e-09 35.6 1.4 8.6e-09 35.1 0.2 1.9 2 0 0 2 2 2 1 C2 domain WW PF00397.21 EGC33108.1 - 1.6e-08 34.2 2.2 4.7e-08 32.7 1.5 1.9 1 0 0 1 1 1 1 WW domain rve_2 PF13333.1 EGC33108.1 - 0.052 13.6 0.3 0.17 12.0 0.2 1.8 1 0 0 1 1 1 0 Integrase core domain An_peroxidase PF03098.10 EGC33109.1 - 4.6e-127 424.6 0.1 5.6e-127 424.3 0.0 1.0 1 0 0 1 1 1 1 Animal haem peroxidase Ribosomal_L19 PF01245.15 EGC33110.1 - 0.055 13.2 0.4 0.055 13.2 0.3 2.1 2 0 0 2 2 2 0 Ribosomal protein L19 DUF722 PF05263.6 EGC33110.1 - 0.39 10.8 8.3 0.8 9.8 5.7 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF722) Coiled PF05710.7 EGC33111.1 - 1.1 9.8 6.4 1.1 9.7 4.4 1.1 1 0 0 1 1 1 0 Coiled coil Peptidase_M14 PF00246.19 EGC33112.1 - 2.9e-71 240.3 0.0 3.4e-71 240.0 0.0 1.1 1 0 0 1 1 1 1 Zinc carboxypeptidase CarboxypepD_reg PF13620.1 EGC33112.1 - 5.8e-07 29.4 0.1 9.2e-07 28.8 0.1 1.3 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain AstE_AspA PF04952.9 EGC33112.1 - 5.4e-05 22.2 0.0 0.00011 21.1 0.0 1.5 1 0 0 1 1 1 1 Succinylglutamate desuccinylase / Aspartoacylase family DUF2817 PF10994.3 EGC33112.1 - 5.9e-05 22.3 0.1 7.8e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2817) DUF4480 PF13715.1 EGC33112.1 - 0.0025 17.7 0.1 0.0049 16.8 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4480) adh_short PF00106.20 EGC33113.1 - 3e-17 63.0 0.0 4.4e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC33113.1 - 0.00023 20.8 0.0 0.00034 20.3 0.0 1.2 1 0 0 1 1 1 1 KR domain PA14 PF07691.7 EGC33115.1 - 1.9e-12 47.0 0.3 3e-12 46.4 0.2 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC33115.1 - 0.0037 17.0 8.5 0.0037 17.0 5.9 13.8 14 3 0 14 14 14 3 Dictyostelium (slime mold) repeat PA14 PF07691.7 EGC33116.1 - 2.3e-12 46.8 0.4 4.4e-12 45.8 0.3 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC33116.1 - 0.00057 19.6 5.9 0.00057 19.6 4.1 13.4 13 4 1 14 14 14 2 Dictyostelium (slime mold) repeat DUF945 PF06097.6 EGC33116.1 - 0.43 9.3 0.7 0.65 8.7 0.5 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF945) Vac14_Fig4_bd PF11916.3 EGC33117.1 - 4.3e-69 231.3 6.9 1.1e-68 230.0 4.8 1.7 1 0 0 1 1 1 1 Vacuolar protein 14 C-terminal Fig4p binding Vac14_Fab1_bd PF12755.2 EGC33117.1 - 5.8e-45 151.6 0.8 3.4e-40 136.3 0.0 4.2 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGC33117.1 - 1.5e-11 43.3 0.4 0.0082 16.1 0.0 6.7 6 0 0 6 6 6 3 HEAT repeat HEAT_2 PF13646.1 EGC33117.1 - 9.9e-08 32.1 0.0 0.29 11.4 0.0 4.7 4 1 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EGC33117.1 - 4.4e-05 23.8 0.0 0.68 10.5 0.0 4.2 3 0 0 3 3 3 2 HEAT-like repeat Arm PF00514.18 EGC33117.1 - 0.0061 16.3 0.2 2.6 7.9 0.0 4.1 4 0 0 4 4 4 1 Armadillo/beta-catenin-like repeat DUF3385 PF11865.3 EGC33117.1 - 0.075 12.9 2.4 66 3.3 0.2 4.3 4 1 0 4 4 4 0 Domain of unknown function (DUF3385) Pkinase PF00069.20 EGC33119.1 - 2.1e-24 86.0 5.7 5.1e-24 84.8 3.1 2.2 1 1 1 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33119.1 - 8.8e-11 41.3 0.8 1.9e-10 40.2 0.6 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33119.1 - 0.029 13.3 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Kinase-like APH PF01636.18 EGC33119.1 - 0.051 13.3 0.0 0.075 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC33119.1 - 0.087 11.8 0.0 0.15 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Pkinase PF00069.20 EGC33120.1 - 2e-14 53.3 6.8 4.4e-13 48.9 4.7 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33120.1 - 5.4e-06 25.6 0.2 3.9e-05 22.8 0.0 1.9 1 1 0 2 2 2 1 Protein tyrosine kinase DUF562 PF04763.7 EGC33120.1 - 0.053 12.7 0.2 0.096 11.9 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF562) Apc9 PF12856.2 EGC33123.1 - 0.0027 17.7 2.4 0.0044 17.0 1.7 1.5 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 9 VTC PF09359.5 EGC33123.1 - 0.013 14.5 1.8 0.015 14.3 1.2 1.1 1 0 0 1 1 1 0 VTC domain UvsW PF11637.3 EGC33124.1 - 0.56 9.9 7.3 0.072 12.7 1.6 2.0 2 0 0 2 2 2 0 ATP-dependant DNA helicase UvsW Ten1_2 PF15490.1 EGC33125.1 - 1.9e-14 53.2 0.3 3.4e-14 52.4 0.2 1.4 1 1 0 1 1 1 1 Telomere-capping, CST complex subunit EGF_2 PF07974.8 EGC33126.1 - 0.24 11.5 6.3 0.31 11.2 3.5 1.9 2 0 0 2 2 2 0 EGF-like domain PseudoU_synth_1 PF01416.15 EGC33127.1 - 1.1e-32 112.5 0.0 1.2e-19 70.6 0.0 2.7 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF1253 PF06862.7 EGC33128.1 - 9.9e-146 485.6 17.8 9.9e-146 485.6 12.3 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF1253) Glyco_transf_7N PF13733.1 EGC33128.1 - 0.084 12.2 2.0 0.11 11.9 0.2 2.0 2 0 0 2 2 2 0 N-terminal region of glycosyl transferase group 7 PRMT5 PF05185.11 EGC33129.1 - 1.3e-16 60.5 2.0 2e-16 59.9 1.4 1.2 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Methyltransf_31 PF13847.1 EGC33129.1 - 9.1e-10 38.3 0.2 3.4e-09 36.4 0.0 2.0 2 1 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGC33129.1 - 4.6e-08 32.5 0.0 7.7e-08 31.7 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC33129.1 - 7.9e-08 32.3 0.0 1.3e-07 31.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC33129.1 - 2e-07 31.5 0.0 3.9e-07 30.6 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC33129.1 - 5.6e-07 29.0 0.2 1.5e-06 27.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGC33129.1 - 5e-05 23.7 0.0 0.00023 21.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC33129.1 - 0.0001 22.6 0.0 0.00025 21.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC33129.1 - 0.0001 22.6 0.0 0.00037 20.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGC33129.1 - 0.00015 21.2 0.2 0.00068 19.0 0.0 2.0 2 0 0 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_9 PF08003.6 EGC33129.1 - 0.0014 17.3 0.0 0.0025 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_23 PF13489.1 EGC33129.1 - 0.0019 17.9 0.0 0.0041 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Rsm22 PF09243.5 EGC33129.1 - 0.0069 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial small ribosomal subunit Rsm22 GATase_4 PF13230.1 EGC33129.1 - 0.035 12.7 0.1 0.066 11.8 0.1 1.4 1 0 0 1 1 1 0 Glutamine amidotransferases class-II Methyltransf_32 PF13679.1 EGC33129.1 - 0.086 12.5 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Rota_NSP4 PF01452.11 EGC33130.1 - 0.072 12.4 0.5 0.13 11.5 0.4 1.6 1 0 0 1 1 1 0 Rotavirus non structural protein Rtt102p PF09510.5 EGC33130.1 - 0.71 9.8 7.0 5.7 6.9 0.7 2.3 1 1 0 2 2 2 0 Rtt102p-like transcription regulator protein Nol1_Nop2_Fmu PF01189.12 EGC33131.1 - 3.5e-21 75.8 0.0 5.1e-21 75.2 0.0 1.2 1 0 0 1 1 1 1 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EGC33131.1 - 0.00032 20.3 0.2 0.00088 18.8 0.1 1.8 2 0 0 2 2 2 1 Methyltransferase domain FtsJ PF01728.14 EGC33131.1 - 0.00064 19.7 0.0 0.0011 18.9 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase zf-primase PF09329.6 EGC33131.1 - 1.2 8.8 4.0 0.71 9.5 0.2 2.6 3 0 0 3 3 3 0 Primase zinc finger NAPRTase PF04095.11 EGC33132.1 - 5.4e-25 88.0 0.0 1.2e-22 80.3 0.0 2.2 1 1 0 1 1 1 1 Nicotinate phosphoribosyltransferase (NAPRTase) family Methyltransf_21 PF05050.7 EGC33132.1 - 0.04 13.8 0.1 0.37 10.7 0.0 2.4 2 0 0 2 2 2 0 Methyltransferase FkbM domain Erf4 PF10256.4 EGC33133.1 - 2.6e-06 27.3 0.8 1.3e-05 25.0 0.5 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Tetraspannin PF00335.15 EGC33133.1 - 0.00072 18.8 0.1 0.00078 18.7 0.1 1.2 1 0 0 1 1 1 1 Tetraspanin family DUF4097 PF13349.1 EGC33133.1 - 0.0057 16.2 1.3 0.87 9.1 0.3 2.4 2 0 0 2 2 2 2 Domain of unknown function (DUF4097) EphA2_TM PF14575.1 EGC33133.1 - 0.025 14.9 0.2 0.086 13.2 0.0 1.9 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain DHFR_1 PF00186.14 EGC33135.1 - 1.7e-34 118.7 0.3 1.6e-33 115.5 0.2 1.9 1 1 0 1 1 1 1 Dihydrofolate reductase DUF1374 PF07118.6 EGC33135.1 - 0.7 10.0 4.6 0.18 11.9 1.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1374) Ank_4 PF13637.1 EGC33136.1 - 9.8e-26 89.6 3.8 9e-10 38.8 0.4 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC33136.1 - 2.3e-24 85.5 3.1 8.7e-17 61.2 0.8 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC33136.1 - 1.2e-21 76.2 0.2 4.6e-10 39.3 0.0 2.9 2 1 2 4 4 4 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC33136.1 - 3.3e-18 64.4 0.5 7.8e-08 31.7 0.1 4.1 4 0 0 4 4 4 3 Ankyrin repeat Ank_3 PF13606.1 EGC33136.1 - 4.9e-14 51.0 0.3 2.1e-05 24.2 0.1 3.6 4 0 0 4 4 4 2 Ankyrin repeat Glyco_hydro_17 PF00332.13 EGC33136.1 - 0.065 12.2 0.4 0.073 12.0 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolases family 17 Mito_carr PF00153.22 EGC33137.1 - 4.6e-11 42.2 0.6 0.00013 21.6 0.0 2.6 2 1 0 2 2 2 2 Mitochondrial carrier protein zf-C2H2_4 PF13894.1 EGC33139.1 - 0.38 11.1 2.8 1.6 9.2 0.1 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger zf-H2C2_5 PF13909.1 EGC33139.1 - 0.63 10.3 3.5 8.2 6.8 0.3 3.1 2 0 0 2 2 2 0 C2H2-type zinc-finger domain zf-C2H2 PF00096.21 EGC33139.1 - 0.65 10.4 3.0 13 6.3 0.1 2.7 2 0 0 2 2 2 0 Zinc finger, C2H2 type Proteasome PF00227.21 EGC33140.1 - 2.5e-53 180.1 0.0 3.5e-53 179.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC33140.1 - 1.3e-14 53.1 0.0 2.6e-14 52.2 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature F-box-like PF12937.2 EGC33141.1 - 8.2e-09 35.0 1.9 1.8e-08 34.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC33141.1 - 2.7e-07 30.0 0.1 2.7e-07 30.0 0.1 3.3 4 0 0 4 4 4 1 F-box domain SprA-related PF12118.3 EGC33141.1 - 0.0057 16.0 12.5 0.008 15.5 8.7 1.3 1 0 0 1 1 1 1 SprA-related family STAS PF01740.16 EGC33141.1 - 0.018 14.4 0.6 0.87 9.0 0.1 2.9 3 0 0 3 3 3 0 STAS domain Erf4 PF10256.4 EGC33143.1 - 1.7e-07 31.0 0.2 1.4e-06 28.1 0.1 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DNA_pol_alpha_N PF12254.3 EGC33143.1 - 0.11 12.2 2.4 0.17 11.7 0.5 1.9 2 0 0 2 2 2 0 DNA polymerase alpha subunit p180 N terminal PCI_Csn8 PF10075.4 EGC33144.1 - 3.3e-23 82.0 1.4 3.3e-23 82.0 1.0 1.6 2 0 0 2 2 2 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGC33144.1 - 5.7e-12 45.6 4.1 8.5e-12 45.0 2.8 1.3 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family PCI PF01399.22 EGC33144.1 - 0.034 14.4 0.1 0.082 13.2 0.0 1.7 1 0 0 1 1 1 0 PCI domain Propeptide_C1 PF08127.8 EGC33144.1 - 0.051 13.2 0.3 0.16 11.5 0.2 1.9 1 0 0 1 1 1 0 Peptidase family C1 propeptide DUF3242 PF11586.3 EGC33144.1 - 0.059 12.9 0.2 0.76 9.3 0.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3242) DIL PF01843.14 EGC33145.1 - 0.00024 20.9 0.2 0.00046 20.0 0.1 1.5 2 0 0 2 2 2 1 DIL domain Med10 PF09748.4 EGC33145.1 - 0.052 13.3 0.3 0.066 13.0 0.2 1.3 1 0 0 1 1 1 0 Transcription factor subunit Med10 of Mediator complex TC1 PF15063.1 EGC33145.1 - 0.069 12.6 0.0 0.17 11.4 0.0 1.6 1 0 0 1 1 1 0 Thyroid cancer protein 1 DUF1856 PF08983.5 EGC33145.1 - 0.079 13.0 0.0 0.13 12.3 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1856) DUF2288 PF10052.4 EGC33147.1 - 0.075 12.7 0.2 0.17 11.6 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2288) SpoIIIAH PF12685.2 EGC33147.1 - 0.34 10.3 7.5 0.071 12.6 1.4 2.1 1 1 1 2 2 2 0 SpoIIIAH-like protein Lipase_3 PF01764.20 EGC33148.1 - 5.4e-35 120.0 0.0 7.5e-35 119.5 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) DUF2974 PF11187.3 EGC33148.1 - 3.2e-07 29.9 0.0 1.2e-06 28.1 0.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_5 PF12695.2 EGC33148.1 - 0.0044 16.7 0.0 0.0054 16.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC33148.1 - 0.057 13.2 0.0 0.074 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGC33148.1 - 0.075 11.9 0.0 0.12 11.2 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase enzyme zf-Di19 PF05605.7 EGC33148.1 - 0.28 11.3 1.5 18 5.5 0.1 3.0 3 0 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding Nup96 PF12110.3 EGC33149.1 - 2.6e-75 253.2 2.0 2.6e-75 253.2 1.4 2.0 2 0 0 2 2 2 1 Nuclear protein 96 Nucleoporin2 PF04096.9 EGC33149.1 - 4.7e-39 133.4 0.0 4.7e-39 133.4 0.0 3.1 3 0 0 3 3 3 1 Nucleoporin autopeptidase Nucleoporin_FG PF13634.1 EGC33149.1 - 0.0017 18.5 9.4 0.0017 18.5 6.5 3.9 3 1 0 3 3 3 1 Nucleoporin FG repeat region Urb2 PF10441.4 EGC33151.1 - 5.9e-09 35.8 2.7 5.9e-09 35.8 1.9 4.2 4 2 1 5 5 5 1 Urb2/Npa2 family NAD_synthase PF02540.12 EGC33152.1 - 2.3e-23 82.3 0.0 5.5e-23 81.1 0.0 1.5 1 0 0 1 1 1 1 NAD synthase CN_hydrolase PF00795.17 EGC33152.1 - 1.1e-21 77.0 0.0 1.7e-21 76.4 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Acetyltransf_2 PF00797.12 EGC33153.1 - 9.6e-20 71.1 0.9 1.3e-19 70.7 0.6 1.1 1 0 0 1 1 1 1 N-acetyltransferase EDR1 PF14381.1 EGC33153.1 - 0.021 14.4 0.0 0.04 13.4 0.0 1.6 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 TGT PF01702.13 EGC33154.1 - 3.3e-16 59.3 0.0 4.9e-16 58.7 0.0 1.2 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Ost4 PF10215.4 EGC33154.1 - 3.8 7.0 4.9 1.2 8.6 1.3 1.7 2 0 0 2 2 2 0 Oligosaccaryltransferase TGT PF01702.13 EGC33155.1 - 8.7e-45 152.8 0.1 9.9e-45 152.6 0.0 1.0 1 0 0 1 1 1 1 Queuine tRNA-ribosyltransferase Granulin PF00396.13 EGC33156.1 - 2.6e-10 40.2 25.5 4.3e-10 39.5 14.2 2.1 2 0 0 2 2 2 2 Granulin Metallothio_6 PF05522.6 EGC33156.1 - 0.47 10.7 22.4 0.74 10.1 15.5 1.3 1 0 0 1 1 1 0 Metallothionein HEAT PF02985.17 EGC33157.1 - 4.4e-47 153.9 25.2 0.00011 22.0 0.0 13.7 14 0 0 14 14 14 11 HEAT repeat HEAT_2 PF13646.1 EGC33157.1 - 1.9e-34 117.8 2.4 8.6e-07 29.1 0.0 6.3 2 1 5 7 7 7 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC33157.1 - 3.9e-11 43.1 1.2 0.087 13.2 0.0 7.1 4 2 5 9 9 9 4 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGC33157.1 - 1.1e-10 40.4 7.9 0.00023 19.6 1.8 3.4 1 1 1 3 3 3 3 Adaptin N terminal region HEAT_EZ PF13513.1 EGC33157.1 - 4.4e-08 33.3 16.5 0.051 14.0 0.0 8.6 7 3 4 12 12 12 2 HEAT-like repeat CLASP_N PF12348.3 EGC33157.1 - 5.8e-08 32.3 0.4 0.14 11.5 0.0 5.1 2 1 1 4 4 4 3 CLASP N terminal Arm PF00514.18 EGC33157.1 - 3.9e-05 23.3 0.7 4.4 7.2 0.0 6.1 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat DUF3554 PF12074.3 EGC33157.1 - 0.00046 19.7 0.8 3.6 6.9 0.0 4.1 2 1 2 4 4 4 1 Domain of unknown function (DUF3554) Cnd1 PF12717.2 EGC33157.1 - 0.0014 18.4 3.6 0.18 11.6 0.2 4.4 1 1 2 4 4 4 1 non-SMC mitotic condensation complex subunit 1 DUF2435 PF10363.4 EGC33157.1 - 0.0051 16.6 2.5 5.6 6.9 0.1 4.7 4 1 1 5 5 5 2 Protein of unknown function (DUF2435) DEAD PF00270.24 EGC33158.1 - 4.1e-47 159.7 0.0 6.9e-47 159.0 0.0 1.4 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC33158.1 - 2.8e-27 94.3 0.0 1.1e-26 92.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC33158.1 - 0.00017 21.4 0.0 0.00048 20.0 0.0 1.8 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit FNIP PF05725.7 EGC33160.1 - 2.9e-99 324.8 27.7 2.9e-14 52.7 1.1 8.2 7 1 1 8 8 8 8 FNIP Repeat Phage_min_tail PF05939.8 EGC33160.1 - 4.1e-05 23.5 0.1 23 5.0 0.0 6.1 1 1 5 7 7 7 1 Phage minor tail protein DUF3215 PF11503.3 EGC33160.1 - 0.01 15.4 0.0 0.16 11.5 0.0 3.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) GLTSCR1 PF15249.1 EGC33161.1 - 1.6e-12 47.5 0.6 1.6e-12 47.5 0.4 2.9 2 0 0 2 2 2 1 Glioma tumor suppressor candidate region Virul_fac_BrkB PF03631.10 EGC33162.1 - 0.00057 19.3 2.9 0.00057 19.3 2.0 2.4 3 0 0 3 3 3 1 Virulence factor BrkB DUF603 PF04645.7 EGC33162.1 - 0.0067 16.3 0.1 0.012 15.6 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF603 Vpu PF00558.14 EGC33162.1 - 0.96 9.0 5.3 2.3 7.8 0.1 3.1 3 0 0 3 3 3 0 Vpu protein DUF805 PF05656.9 EGC33162.1 - 3.7 7.4 13.6 1.6e+02 2.1 9.4 2.8 1 1 0 1 1 1 0 Protein of unknown function (DUF805) Acetyltransf_9 PF13527.1 EGC33163.1 - 0.074 12.9 0.0 0.15 11.9 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain UCR_UQCRX_QCR9 PF05365.7 EGC33164.1 - 9.5e-16 57.1 1.6 1e-15 57.0 1.1 1.0 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase, UQCRX/QCR9 like DUF2042 PF09743.4 EGC33165.1 - 4.1e-72 242.7 14.6 4.1e-72 242.7 10.1 2.4 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2042) HTH_9 PF08221.6 EGC33165.1 - 0.06 13.2 0.1 0.35 10.7 0.0 2.3 1 0 0 1 1 1 0 RNA polymerase III subunit RPC82 helix-turn-helix domain Pro_isomerase PF00160.16 EGC33166.1 - 2e-49 167.7 0.3 3.3e-49 167.0 0.2 1.4 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD TPR_11 PF13414.1 EGC33166.1 - 1.5e-19 69.3 4.1 2e-15 56.1 0.2 2.3 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC33166.1 - 4.1e-15 54.3 6.1 2.8e-05 23.7 0.1 4.0 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGC33166.1 - 6.6e-15 53.9 15.3 9.6e-09 34.4 0.5 3.7 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC33166.1 - 3.2e-13 49.4 2.1 9.4e-09 35.0 0.0 2.4 1 1 2 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC33166.1 - 1.1e-08 35.2 10.7 1.8e-05 25.0 0.8 2.8 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGC33166.1 - 1.7e-07 30.9 7.6 0.0013 18.7 0.2 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC33166.1 - 2.3e-06 28.0 0.0 0.0053 17.3 0.0 3.1 2 1 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC33166.1 - 3.1e-06 26.5 0.6 0.033 13.9 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat DUF3808 PF10300.4 EGC33166.1 - 8.5e-06 24.5 1.9 1.2e-05 24.1 1.3 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3808) Fis1_TPR_C PF14853.1 EGC33166.1 - 1.3e-05 25.0 6.6 0.0061 16.4 0.9 3.7 2 1 1 3 3 3 1 Fis1 C-terminal tetratricopeptide repeat TPR_8 PF13181.1 EGC33166.1 - 1.3e-05 24.6 13.5 0.0028 17.2 0.3 4.1 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC33166.1 - 0.00026 21.3 0.0 1.1 10.0 0.0 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC33166.1 - 0.00026 21.2 2.8 0.7 10.4 0.1 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGC33166.1 - 0.0003 20.8 4.9 0.0057 16.7 3.4 2.3 1 1 0 1 1 1 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC33166.1 - 0.00047 19.9 0.0 0.036 13.9 0.0 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC33166.1 - 0.00055 19.7 0.0 0.00089 19.0 0.0 1.3 1 0 0 1 1 1 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC33166.1 - 0.00055 20.0 6.3 0.0034 17.4 3.9 2.3 1 1 1 2 2 2 1 Anaphase-promoting complex, cyclosome, subunit 3 UxuA PF03786.8 EGC33166.1 - 0.076 11.5 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 D-mannonate dehydratase (UxuA) PPR PF01535.15 EGC33166.1 - 0.51 10.4 4.1 5.4 7.2 0.1 3.5 4 0 0 4 4 3 0 PPR repeat Pkinase_Tyr PF07714.12 EGC33167.1 - 7.1e-67 225.2 0.0 9.6e-67 224.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC33167.1 - 5.8e-53 179.6 0.0 1e-52 178.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC33167.1 - 6.6e-06 25.2 0.0 1.1e-05 24.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGC33167.1 - 0.0041 15.9 1.3 0.012 14.4 0.1 2.2 2 1 1 3 3 3 1 Seadornavirus VP7 Kdo PF06293.9 EGC33167.1 - 0.0095 15.0 0.0 0.015 14.3 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC33167.1 - 0.11 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family RabGAP-TBC PF00566.13 EGC33168.1 - 3.8e-41 140.9 8.7 3.8e-41 140.9 6.0 4.4 3 2 0 3 3 3 1 Rab-GTPase-TBC domain MR_MLE_C PF13378.1 EGC33168.1 - 3.9e-11 42.8 0.0 6.8e-11 42.1 0.0 1.4 1 0 0 1 1 1 1 Enolase C-terminal domain-like EF-hand_6 PF13405.1 EGC33168.1 - 0.00019 21.0 10.5 0.0029 17.3 0.3 4.0 3 0 0 3 3 3 2 EF-hand domain MR_MLE PF01188.16 EGC33168.1 - 0.00025 21.4 0.0 0.00063 20.2 0.0 1.6 1 0 0 1 1 1 1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain MR_MLE_N PF02746.11 EGC33168.1 - 0.00055 19.9 0.0 0.62 10.0 0.0 2.4 2 0 0 2 2 2 2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain EF-hand_1 PF00036.27 EGC33168.1 - 0.0006 18.9 0.7 0.0006 18.9 0.5 3.4 3 0 0 3 3 3 1 EF hand EF-hand_7 PF13499.1 EGC33168.1 - 0.00082 19.4 3.1 0.00082 19.4 2.1 3.7 5 1 0 5 5 5 1 EF-hand domain pair MAAL_C PF07476.6 EGC33168.1 - 0.0052 15.7 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Methylaspartate ammonia-lyase C-terminus EF-hand_5 PF13202.1 EGC33168.1 - 0.044 13.1 2.6 0.11 11.9 0.7 2.5 2 0 0 2 2 2 0 EF hand S-methyl_trans PF02574.11 EGC33169.1 - 1.3e-96 323.5 0.0 2.6e-96 322.5 0.0 1.6 1 0 0 1 1 1 1 Homocysteine S-methyltransferase Met_synt_B12 PF02965.12 EGC33169.1 - 6.6e-72 241.1 0.2 3.1e-71 238.9 0.0 2.0 2 0 0 2 2 2 1 Vitamin B12 dependent methionine synthase, activation domain Pterin_bind PF00809.17 EGC33169.1 - 3.9e-43 147.2 0.2 9.3e-43 146.0 0.2 1.7 1 0 0 1 1 1 1 Pterin binding enzyme B12-binding_2 PF02607.12 EGC33169.1 - 2.5e-19 69.0 0.0 1.8e-18 66.3 0.0 2.6 2 0 0 2 2 2 1 B12 binding domain B12-binding PF02310.14 EGC33169.1 - 1.5e-17 63.5 0.2 5.5e-17 61.7 0.2 2.0 1 0 0 1 1 1 1 B12 binding domain MCLC PF05934.6 EGC33170.1 - 2.9 6.0 7.1 4.5 5.4 4.9 1.2 1 0 0 1 1 1 0 Mid-1-related chloride channel (MCLC) Methyltransf_12 PF08242.7 EGC33171.1 - 2.8e-16 59.7 1.1 9.7e-16 58.0 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC33171.1 - 1.4e-08 34.4 0.2 1.4e-08 34.4 0.1 2.9 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC33171.1 - 1.4e-07 31.3 0.0 2.8e-07 30.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC33171.1 - 8.8e-07 29.3 0.0 3.1e-06 27.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Utp21 PF04192.7 EGC33172.1 - 0.0032 16.6 5.4 0.005 15.9 3.7 1.2 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Peptidase_C50 PF03568.12 EGC33173.1 - 4.6e-61 206.5 1.0 4.6e-61 206.5 0.7 4.8 3 1 0 3 3 3 1 Peptidase family C50 CHAT PF12770.2 EGC33173.1 - 5.7e-07 28.9 0.1 6.6e-05 22.1 0.0 3.3 3 1 0 3 3 3 1 CHAT domain TPR_11 PF13414.1 EGC33173.1 - 1e-05 25.1 2.1 0.25 11.0 0.0 6.1 5 2 2 7 7 7 1 TPR repeat TPR_12 PF13424.1 EGC33173.1 - 1.1e-05 25.2 0.8 3.5 7.6 0.0 6.2 8 0 0 8 8 8 2 Tetratricopeptide repeat PA14 PF07691.7 EGC33174.1 - 5.9e-14 51.9 0.3 9.9e-14 51.2 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC33174.1 - 7.7e-07 28.8 37.1 5.2e-05 22.9 3.5 10.7 12 0 0 12 12 12 5 Dictyostelium (slime mold) repeat IpaC_SipC PF09599.5 EGC33174.1 - 1.1 8.2 1.2 1.5 7.7 0.9 1.1 1 0 0 1 1 1 0 Salmonella-Shigella invasin protein C (IpaC_SipC) DUF179 PF02622.10 EGC33175.1 - 3.1e-25 88.6 0.0 5.4e-25 87.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized ACR, COG1678 CBM49 PF09478.5 EGC33176.1 - 6.5e-05 22.9 1.3 7.3e-05 22.7 0.2 1.6 2 1 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF3868 PF12984.2 EGC33176.1 - 0.076 12.5 0.6 1.2 8.6 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF3868) Ras PF00071.17 EGC33177.1 - 4e-31 107.5 5.9 7.6e-31 106.6 4.1 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC33177.1 - 5.6e-13 49.4 0.1 2.4e-12 47.3 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC33177.1 - 3.4e-09 36.1 0.2 5e-09 35.6 0.1 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC33177.1 - 0.00042 19.8 1.8 0.0008 18.8 1.2 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Di19_C PF14571.1 EGC33177.1 - 7.4 6.9 7.3 0.29 11.4 0.2 2.2 3 0 0 3 3 3 0 Stress-induced protein Di19, C-terminal Porphobil_deam PF01379.15 EGC33179.1 - 7.5e-85 283.2 0.1 9.6e-85 282.8 0.0 1.1 1 0 0 1 1 1 1 Porphobilinogen deaminase, dipyromethane cofactor binding domain Porphobil_deamC PF03900.10 EGC33179.1 - 1.2e-21 76.5 0.1 2.9e-21 75.3 0.0 1.7 1 0 0 1 1 1 1 Porphobilinogen deaminase, C-terminal domain Pkinase PF00069.20 EGC33180.1 - 5.5e-34 117.4 0.1 5.5e-34 117.4 0.1 2.3 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33180.1 - 5.3e-14 51.9 0.0 1.6e-13 50.3 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase zf-RING_2 PF13639.1 EGC33180.1 - 1.7e-07 30.9 4.4 3.4e-07 29.9 3.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC33180.1 - 2.7e-07 30.1 7.4 5.8e-07 29.0 5.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33180.1 - 2.2e-05 24.1 7.2 4.8e-05 22.9 5.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC33180.1 - 6.7e-05 22.4 6.7 0.00017 21.1 4.6 1.7 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC33180.1 - 0.00055 19.7 4.4 0.0017 18.2 3.0 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGC33180.1 - 0.00097 19.1 7.6 0.0046 16.9 5.4 2.2 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Kinase-like PF14531.1 EGC33180.1 - 0.0012 17.8 0.0 0.0025 16.8 0.0 1.5 1 0 0 1 1 1 1 Kinase-like zf-rbx1 PF12678.2 EGC33180.1 - 0.0047 16.9 5.5 0.01 15.9 2.8 2.2 1 1 1 2 2 2 2 RING-H2 zinc finger zf-Apc11 PF12861.2 EGC33180.1 - 0.01 15.6 0.4 0.022 14.5 0.3 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC33180.1 - 0.015 14.8 6.4 0.043 13.4 4.5 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF3584 PF12128.3 EGC33180.1 - 0.046 11.0 36.2 0.31 8.3 16.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) zf-RING_UBOX PF13445.1 EGC33180.1 - 0.24 11.1 6.9 0.4 10.4 2.8 2.9 1 1 1 2 2 2 0 RING-type zinc-finger Phage_lysis PF03245.8 EGC33180.1 - 0.35 10.8 18.7 0.052 13.5 3.3 2.7 2 1 1 3 3 3 0 Bacteriophage Rz lysis protein TK PF00265.13 EGC33181.1 - 3.3e-66 222.1 1.4 4.9e-66 221.6 1.0 1.2 1 0 0 1 1 1 1 Thymidine kinase AAA_14 PF13173.1 EGC33181.1 - 1.9e-05 24.5 0.2 3.6e-05 23.6 0.1 1.5 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGC33181.1 - 0.0009 19.0 0.2 0.0011 18.6 0.2 1.2 1 0 0 1 1 1 1 Archaeal ATPase Pro-kuma_activ PF09286.6 EGC33182.1 - 7.4e-35 120.0 0.4 1.3e-34 119.3 0.3 1.4 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC33182.1 - 1.6e-08 34.0 0.7 4e-08 32.7 0.5 1.6 1 1 0 1 1 1 1 Subtilase family TFIIA PF03153.8 EGC33183.1 - 1.1e-38 134.1 32.7 1.3e-24 87.7 12.9 2.6 1 1 1 2 2 2 2 Transcription factor IIA, alpha/beta subunit Dicty_REP PF05086.7 EGC33183.1 - 0.65 7.6 13.2 0.13 10.0 6.8 1.6 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein ABC2_membrane_3 PF12698.2 EGC33183.1 - 0.81 8.6 4.4 1.3 7.9 3.0 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein YppG PF14179.1 EGC33183.1 - 9 6.9 12.2 59 4.3 8.6 2.0 1 1 0 1 1 1 0 YppG-like protein adh_short PF00106.20 EGC33184.1 - 8.7e-18 64.7 0.0 1.1e-17 64.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC33184.1 - 8.2e-10 38.8 0.0 1.2e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGC33184.1 - 7.4e-05 22.0 0.1 0.00015 21.0 0.1 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EGC33184.1 - 8.7e-05 22.2 0.0 0.00016 21.4 0.0 1.4 1 1 0 1 1 1 1 KR domain SSrecog PF03531.9 EGC33185.1 - 1.7e-72 243.3 10.5 6.5e-45 153.1 0.3 2.2 2 0 0 2 2 2 2 Structure-specific recognition protein (SSRP1) Rtt106 PF08512.7 EGC33185.1 - 9.3e-32 108.8 0.1 6.2e-27 93.4 0.0 2.8 3 0 0 3 3 3 2 Histone chaperone Rttp106-like FAT PF02259.18 EGC33185.1 - 0.0024 16.9 0.0 0.0045 16.0 0.0 1.4 1 0 0 1 1 1 1 FAT domain FAM176 PF14851.1 EGC33185.1 - 0.0047 16.6 4.3 0.0047 16.6 3.0 2.4 2 0 0 2 2 1 1 FAM176 family BUD22 PF09073.5 EGC33185.1 - 0.017 14.2 34.3 0.075 12.0 5.4 2.1 2 0 0 2 2 2 0 BUD22 SDA1 PF05285.7 EGC33185.1 - 0.052 12.8 33.7 0.15 11.3 9.6 2.2 2 0 0 2 2 2 0 SDA1 TFIIA PF03153.8 EGC33185.1 - 0.11 12.3 19.6 0.027 14.3 0.8 2.1 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 EGC33185.1 - 0.32 10.1 21.3 0.37 9.9 6.1 2.1 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Cwf_Cwc_15 PF04889.7 EGC33185.1 - 2.5 7.7 25.3 0.49 10.0 5.7 2.3 2 0 0 2 2 2 0 Cwf15/Cwc15 cell cycle control protein Tom37_C PF11801.3 EGC33185.1 - 2.9 7.7 14.6 0.038 13.8 0.7 2.9 3 0 0 3 3 3 0 Tom37 C-terminal domain Paf1 PF03985.8 EGC33185.1 - 3.1 6.4 36.6 0.14 10.9 10.3 2.2 2 0 0 2 2 2 0 Paf1 DDHD PF02862.12 EGC33185.1 - 3.5 7.3 8.6 1.8 8.3 0.4 2.4 2 0 0 2 2 2 0 DDHD domain DUF2201_N PF13203.1 EGC33185.1 - 8.6 5.4 9.5 6 5.9 0.8 2.1 2 0 0 2 2 2 0 Putative metallopeptidase domain Ribonucleas_3_3 PF14622.1 EGC33186.1 - 6.9e-06 26.0 0.0 1.7e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGC33186.1 - 0.0011 19.4 0.1 0.0011 19.4 0.0 3.7 3 1 0 3 3 3 2 Ribonuclease III domain Gti1_Pac2 PF09729.4 EGC33186.1 - 0.71 9.7 15.7 1.4 8.7 1.8 2.3 2 0 0 2 2 2 0 Gti1/Pac2 family RINGv PF12906.2 EGC33187.1 - 4.2e-07 29.9 9.8 4.2e-07 29.9 6.8 2.6 2 0 0 2 2 2 1 RING-variant domain Erf4 PF10256.4 EGC33188.1 - 7.9e-11 41.8 0.1 1.3e-10 41.2 0.1 1.3 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Frizzled PF01534.12 EGC33188.1 - 0.095 11.4 0.1 0.11 11.2 0.1 1.1 1 0 0 1 1 1 0 Frizzled/Smoothened family membrane region Peptidase_M15_2 PF05951.8 EGC33188.1 - 0.12 11.8 0.1 0.2 11.0 0.0 1.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF882) Tom22 PF04281.8 EGC33188.1 - 0.16 11.4 0.0 0.17 11.3 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 RNA_pol_Rbc25 PF08292.7 EGC33189.1 - 3.8e-32 111.0 0.6 6.3e-32 110.3 0.4 1.4 1 0 0 1 1 1 1 RNA polymerase III subunit Rpc25 SHS2_Rpb7-N PF03876.12 EGC33189.1 - 1.3e-13 50.8 0.3 3.2e-13 49.6 0.1 1.7 2 0 0 2 2 2 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 S1 PF00575.18 EGC33189.1 - 0.15 12.1 0.7 2.4 8.2 0.1 2.6 2 0 0 2 2 2 0 S1 RNA binding domain CAP PF00188.21 EGC33190.1 - 1.8e-13 51.0 7.8 1.8e-13 51.0 5.4 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Ephrin PF00812.12 EGC33190.1 - 0.13 11.7 0.3 0.13 11.7 0.2 2.0 2 0 0 2 2 2 0 Ephrin CAP PF00188.21 EGC33191.1 - 3.4e-15 56.6 2.2 7e-15 55.6 1.5 1.5 1 0 0 1 1 1 1 Cysteine-rich secretory protein family CAP PF00188.21 EGC33192.1 - 6.1e-20 71.9 2.0 6.1e-20 71.9 1.4 2.2 2 2 0 2 2 2 1 Cysteine-rich secretory protein family Transglut_core PF01841.14 EGC33193.1 - 4.4e-14 52.6 0.0 8.5e-14 51.7 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily Ribonuc_red_sm PF00268.16 EGC33194.1 - 2.7e-121 403.8 1.4 3.3e-121 403.6 0.9 1.1 1 0 0 1 1 1 1 Ribonucleotide reductase, small chain Transketolase_N PF00456.16 EGC33195.1 - 1.6e-112 375.6 0.1 2.4e-112 375.0 0.1 1.3 1 0 0 1 1 1 1 Transketolase, thiamine diphosphate binding domain Transket_pyr PF02779.19 EGC33195.1 - 2.7e-42 144.2 0.0 5.6e-42 143.2 0.0 1.5 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain DXP_synthase_N PF13292.1 EGC33195.1 - 1.5e-12 47.0 0.1 1.2e-08 34.2 0.0 2.6 1 1 1 2 2 2 2 1-deoxy-D-xylulose-5-phosphate synthase Transketolase_C PF02780.15 EGC33195.1 - 6e-10 39.1 0.0 6.3e-09 35.8 0.0 2.5 3 0 0 3 3 3 1 Transketolase, C-terminal domain TPP_enzyme_C PF02775.16 EGC33195.1 - 1.3e-05 24.8 0.0 0.00025 20.6 0.0 2.5 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain E1_dh PF00676.15 EGC33195.1 - 0.022 13.4 0.1 0.038 12.7 0.1 1.3 1 0 0 1 1 1 0 Dehydrogenase E1 component Sybindin PF04099.7 EGC33196.1 - 5.3e-36 123.4 1.6 5.9e-36 123.3 1.1 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGC33196.1 - 0.00051 19.9 0.7 0.00082 19.2 0.5 1.3 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region AAA PF00004.24 EGC33197.1 - 7.2e-07 29.4 0.7 0.00015 22.0 0.0 4.5 4 0 0 4 4 4 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC33197.1 - 0.00022 21.2 0.0 2.1 8.3 0.0 4.0 3 0 0 3 3 3 3 AAA ATPase domain Adaptin_N PF01602.15 EGC33198.1 - 3.7e-115 385.2 5.9 4.5e-115 384.9 4.1 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptin_C PF02296.11 EGC33198.1 - 2.6e-35 120.7 1.2 1e-34 118.8 0.0 2.7 4 0 0 4 4 4 1 Alpha adaptin AP2, C-terminal domain Alpha_adaptinC2 PF02883.15 EGC33198.1 - 2.3e-19 69.8 1.1 2.3e-19 69.8 0.7 2.6 3 0 0 3 3 3 1 Adaptin C-terminal domain HEAT_2 PF13646.1 EGC33198.1 - 0.00019 21.6 0.2 0.11 12.7 0.0 3.3 3 0 0 3 3 3 2 HEAT repeats Chordopox_G3 PF06129.7 EGC33199.1 - 1.4 9.1 5.8 5.3 7.2 0.8 2.4 2 0 0 2 2 2 0 Chordopoxvirus G3 protein DUF1180 PF06679.7 EGC33200.1 - 0.0061 16.4 0.3 0.0095 15.8 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) SHOCT PF09851.4 EGC33200.1 - 0.0092 15.4 1.1 0.016 14.6 0.8 1.3 1 0 0 1 1 1 1 Short C-terminal domain DUF829 PF05705.9 EGC33202.1 - 2e-48 165.2 0.2 2.6e-48 164.8 0.2 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) DUF2515 PF10720.4 EGC33202.1 - 0.0014 17.6 1.8 0.0014 17.6 1.3 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF2515) TFIIE_alpha PF02002.12 EGC33203.1 - 1e-14 53.9 6.4 2.8e-14 52.5 4.4 1.8 1 0 0 1 1 1 1 TFIIE alpha subunit Rrf2 PF02082.15 EGC33203.1 - 0.0068 16.4 0.5 0.018 15.1 0.1 1.9 2 0 0 2 2 2 1 Transcriptional regulator HrcA_DNA-bdg PF03444.10 EGC33203.1 - 0.042 13.2 0.3 0.15 11.5 0.2 1.9 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding GrpB PF04229.9 EGC33204.1 - 2.8e-38 131.2 0.0 3.4e-38 130.9 0.0 1.0 1 0 0 1 1 1 1 GrpB protein DUF1794 PF08768.6 EGC33205.1 - 2.4e-36 124.9 0.0 2.6e-36 124.7 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1794) Cofilin_ADF PF00241.15 EGC33206.1 - 9e-14 51.4 0.4 1e-13 51.2 0.3 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein XAP5 PF04921.9 EGC33207.1 - 1.4e-89 299.8 16.5 1.5e-89 299.6 11.5 1.0 1 0 0 1 1 1 1 XAP5, circadian clock regulator SMN PF06003.7 EGC33207.1 - 0.0036 16.4 6.0 0.0061 15.6 4.2 1.3 1 0 0 1 1 1 1 Survival motor neuron protein (SMN) Radical_SAM PF04055.16 EGC33207.1 - 0.13 12.4 0.9 0.54 10.4 0.7 1.9 1 1 0 1 1 1 0 Radical SAM superfamily CDC45 PF02724.9 EGC33207.1 - 3 5.7 15.8 3.8 5.4 10.9 1.1 1 0 0 1 1 1 0 CDC45-like protein Microtub_bind PF13931.1 EGC33207.1 - 5.8 7.0 11.6 10 6.2 8.0 1.5 1 0 0 1 1 1 0 Kinesin-associated microtubule-binding CBM49 PF09478.5 EGC33208.1 - 5.4e-13 48.8 3.9 8.1e-13 48.2 2.7 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Kinesin PF00225.18 EGC33210.1 - 2.6e-91 305.8 1.2 2.9e-91 305.6 0.8 1.0 1 0 0 1 1 1 1 Kinesin motor domain ALG3 PF05208.8 EGC33212.1 - 2e-122 408.9 44.5 1.9e-88 297.1 21.2 2.0 2 0 0 2 2 2 2 ALG3 protein DUF2839 PF10999.3 EGC33212.1 - 0.013 15.5 5.5 0.15 12.0 0.0 3.6 2 1 1 3 3 3 0 Protein of unknown function (DUF2839) Seryl_tRNA_N PF02403.17 EGC33213.1 - 0.0083 16.1 11.9 0.0083 16.1 8.3 6.6 3 1 2 6 6 6 2 Seryl-tRNA synthetase N-terminal domain HalX PF08663.5 EGC33213.1 - 0.013 15.4 1.0 0.013 15.4 0.7 3.8 3 0 0 3 3 3 0 HalX domain NPV_P10 PF05531.7 EGC33213.1 - 4.6 7.5 19.0 9.4 6.5 0.2 4.6 3 2 2 5 5 5 0 Nucleopolyhedrovirus P10 protein zf-RING_2 PF13639.1 EGC33215.1 - 1.8e-10 40.4 11.9 3.1e-10 39.7 8.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC33215.1 - 6e-07 29.0 8.1 1e-06 28.2 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33215.1 - 8.1e-07 29.0 6.0 1.9e-06 27.9 4.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC33215.1 - 1.9e-06 27.4 14.4 3.8e-06 26.4 10.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33215.1 - 2.7e-06 27.2 13.8 4.8e-06 26.4 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33215.1 - 0.00022 20.8 13.0 0.00043 19.9 9.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC33215.1 - 0.0023 17.7 3.8 0.0051 16.6 2.6 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC33215.1 - 0.031 14.1 13.4 0.085 12.7 9.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING TFIIA PF03153.8 EGC33215.1 - 0.85 9.4 46.2 1.7 8.4 32.0 1.5 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-RING_UBOX PF13445.1 EGC33215.1 - 1.1 9.0 8.1 5 6.9 5.6 2.3 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC33215.1 - 1.5 8.7 8.6 3.2 7.6 6.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FAINT PF04385.10 EGC33216.1 - 0.064 13.1 1.4 0.083 12.7 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function, DUF529 DUF1771 PF08590.5 EGC33217.1 - 6.3e-18 64.5 9.9 9.4e-18 64.0 6.9 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGC33217.1 - 2.4e-11 43.6 0.1 6.2e-11 42.3 0.0 1.7 1 0 0 1 1 1 1 Smr domain eIF-3_zeta PF05091.7 EGC33217.1 - 0.035 12.7 2.0 0.046 12.3 1.4 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) DUF1151 PF06625.6 EGC33217.1 - 0.19 11.5 6.7 0.33 10.7 4.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1151) TIG PF01833.19 EGC33218.1 - 9.8e-10 38.3 34.8 1.3e-05 25.1 1.0 6.5 6 0 0 6 6 6 4 IPT/TIG domain CARDB PF07705.6 EGC33218.1 - 0.0071 16.3 1.3 0.0071 16.3 0.9 3.4 3 0 0 3 3 3 1 CARDB DUF936 PF06075.7 EGC33219.1 - 7.1 5.4 19.8 8.6 5.1 13.7 1.2 1 0 0 1 1 1 0 Plant protein of unknown function (DUF936) OTU PF02338.14 EGC33220.1 - 9.7e-12 45.5 0.1 1.2e-11 45.2 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease ECSIT PF06239.6 EGC33220.1 - 0.084 11.7 0.0 0.16 10.7 0.0 1.3 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway FNIP PF05725.7 EGC33221.1 - 9.9e-09 35.0 12.1 5e-05 23.1 0.3 8.4 8 1 1 9 9 9 5 FNIP Repeat DUF4181 PF13789.1 EGC33222.1 - 0.76 9.7 12.0 1.8 8.5 8.1 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4181) zf-DHHC PF01529.15 EGC33222.1 - 0.89 8.9 8.2 1.1 8.6 5.7 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase NfeD PF01957.13 EGC33222.1 - 1.3 9.1 4.2 12 6.0 0.5 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF2839 PF10999.3 EGC33222.1 - 6.1 6.9 5.9 3.5 7.7 1.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2839) Sigma_reg_N PF13800.1 EGC33222.1 - 6.2 6.9 13.8 6 6.9 4.2 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal Guanylate_cyc PF00211.15 EGC33223.1 - 4.9e-28 97.7 1.1 1.3e-27 96.3 0.8 1.7 1 0 0 1 1 1 1 Adenylate and Guanylate cyclase catalytic domain HATPase_c PF02518.21 EGC33223.1 - 2.2e-20 72.4 0.1 6.8e-20 70.8 0.0 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC33223.1 - 4.8e-15 55.5 0.1 9e-08 32.1 0.1 3.0 2 0 0 2 2 2 2 Response regulator receiver domain DUF4064 PF13273.1 EGC33223.1 - 0.0038 17.3 0.1 0.0038 17.3 0.0 4.6 4 1 1 5 5 5 1 Protein of unknown function (DUF4064) TPR_2 PF07719.12 EGC33223.1 - 0.018 14.9 0.2 0.042 13.7 0.1 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat UPF0233 PF06781.7 EGC33223.1 - 8.3 6.1 8.9 0.86 9.2 0.0 3.3 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0233) PTS_EIIB PF00367.15 EGC33224.1 - 0.14 11.4 0.3 0.58 9.4 0.0 1.9 2 0 0 2 2 2 0 phosphotransferase system, EIIB AIG1 PF04548.11 EGC33225.1 - 4.3e-05 22.7 0.0 4.8e-05 22.5 0.0 1.0 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EGC33225.1 - 0.00017 21.5 0.0 0.00018 21.4 0.0 1.0 1 0 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC33225.1 - 0.031 14.1 0.0 0.031 14.0 0.0 1.1 1 0 0 1 1 1 0 Dynamin family GTP_EFTU PF00009.22 EGC33225.1 - 0.04 13.3 0.1 0.053 12.9 0.0 1.3 1 0 0 1 1 1 0 Elongation factor Tu GTP binding domain AIG1 PF04548.11 EGC33226.1 - 3.7e-10 39.2 1.9 1.1e-09 37.7 1.3 1.8 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EGC33226.1 - 6.9e-10 38.9 0.7 2.7e-09 36.9 0.5 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC33226.1 - 7.6e-05 22.2 0.3 7.6e-05 22.2 0.2 3.1 3 0 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGC33226.1 - 0.00018 20.9 0.2 0.00044 19.7 0.1 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC33226.1 - 0.00074 19.6 0.1 0.022 14.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain zinc_ribbon_4 PF13717.1 EGC33226.1 - 0.0013 18.4 41.5 0.062 13.0 1.2 6.6 6 0 0 6 6 6 4 zinc-ribbon domain T2SE PF00437.15 EGC33226.1 - 0.0018 17.2 0.4 0.0043 16.0 0.3 1.7 1 0 0 1 1 1 1 Type II/IV secretion system protein Dynamin_N PF00350.18 EGC33226.1 - 0.0022 17.8 18.5 0.099 12.4 0.1 4.6 4 2 0 4 4 4 2 Dynamin family ABC_tran PF00005.22 EGC33226.1 - 0.0041 17.4 4.8 0.0064 16.7 0.0 3.3 2 1 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 EGC33226.1 - 0.0065 15.9 2.3 0.007 15.8 0.1 2.1 2 1 0 2 2 2 1 AAA-like domain zinc_ribbon_5 PF13719.1 EGC33226.1 - 0.0083 15.6 41.9 0.081 12.5 1.2 6.5 6 0 0 6 6 6 4 zinc-ribbon domain MobB PF03205.9 EGC33226.1 - 0.012 15.2 0.0 0.037 13.7 0.0 1.9 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B FtsK_SpoIIIE PF01580.13 EGC33226.1 - 0.016 14.6 0.1 0.034 13.6 0.1 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_16 PF13191.1 EGC33226.1 - 0.023 14.6 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain V-SNARE PF05008.10 EGC33226.1 - 0.044 13.9 8.4 0.045 13.8 0.1 3.9 3 0 0 3 3 3 0 Vesicle transport v-SNARE protein N-terminus DUF87 PF01935.12 EGC33226.1 - 0.075 12.8 0.0 0.075 12.8 0.0 3.5 3 1 1 4 4 4 0 Domain of unknown function DUF87 AIG1 PF04548.11 EGC33227.1 - 8.3e-11 41.3 2.7 3.7e-10 39.2 1.9 2.1 1 1 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EGC33227.1 - 2.3e-09 37.2 0.9 2.3e-09 37.2 0.6 2.3 2 0 0 2 2 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC33227.1 - 0.00018 21.0 2.2 0.00032 20.1 0.1 2.5 2 1 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC33227.1 - 0.0012 18.9 0.6 0.019 15.1 0.0 2.9 3 0 0 3 3 3 1 AAA domain AAA_29 PF13555.1 EGC33227.1 - 0.002 17.5 0.1 0.0042 16.5 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC33227.1 - 0.0024 18.1 0.0 0.0024 18.1 0.0 2.9 2 1 0 2 2 1 1 ABC transporter Dynamin_N PF00350.18 EGC33227.1 - 0.0076 16.0 0.8 0.06 13.1 0.1 6.1 5 2 1 6 6 4 3 Dynamin family PRK PF00485.13 EGC33227.1 - 0.0083 15.7 0.1 0.039 13.5 0.1 2.2 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_16 PF13191.1 EGC33227.1 - 0.0095 15.9 0.0 0.028 14.3 0.0 1.8 2 0 0 2 2 2 1 AAA ATPase domain T2SE PF00437.15 EGC33227.1 - 0.014 14.2 0.3 0.032 13.1 0.2 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EGC33227.1 - 0.028 13.8 4.7 0.07 12.5 1.6 2.6 2 1 0 2 2 2 0 AAA-like domain NACHT PF05729.7 EGC33227.1 - 0.061 12.9 0.0 0.17 11.5 0.0 1.7 1 0 0 1 1 1 0 NACHT domain FtsK_SpoIIIE PF01580.13 EGC33227.1 - 0.17 11.3 0.1 0.47 9.8 0.1 1.7 1 0 0 1 1 1 0 FtsK/SpoIIIE family DUF1759 PF03564.10 EGC33227.1 - 0.36 10.6 13.9 0.044 13.5 0.7 4.0 3 2 2 5 5 5 0 Protein of unknown function (DUF1759) DUF87 PF01935.12 EGC33227.1 - 0.46 10.2 0.0 0.46 10.2 0.0 3.8 3 1 0 3 3 3 0 Domain of unknown function DUF87 Syntaxin-6_N PF09177.6 EGC33227.1 - 4.1 7.8 21.0 0.14 12.5 1.5 3.9 2 1 1 3 3 3 0 Syntaxin 6, N-terminal DDE_Tnp_1_7 PF13843.1 EGC33232.1 - 1.1e-16 60.8 3.3 1.3e-16 60.5 2.3 1.1 1 0 0 1 1 1 1 Transposase IS4 V_ATPase_I PF01496.14 EGC33232.1 - 0.015 13.2 1.5 0.35 8.6 0.0 2.0 2 0 0 2 2 2 0 V-type ATPase 116kDa subunit family BaffR-Tall_bind PF09256.5 EGC33232.1 - 0.056 13.0 0.0 0.11 12.1 0.0 1.5 1 0 0 1 1 1 0 BAFF-R, TALL-1 binding DUF1363 PF07101.6 EGC33232.1 - 0.82 9.7 4.8 4.4 7.3 0.1 3.1 3 1 0 3 3 3 0 Protein of unknown function (DUF1363) Flagellar_rod PF05149.7 EGC33233.1 - 0.035 13.3 0.5 0.39 9.8 0.0 2.0 1 1 1 2 2 2 0 Paraflagellar rod protein DUF1049 PF06305.6 EGC33233.1 - 0.068 12.6 0.0 0.3 10.5 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Aminotran_1_2 PF00155.16 EGC33234.1 - 5.3e-24 84.8 0.0 6.5e-24 84.5 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II WD40 PF00400.27 EGC33238.1 - 8.7e-09 34.9 3.0 2.7e-05 23.8 0.1 5.5 7 0 0 7 7 7 3 WD domain, G-beta repeat Ribosomal_L11_N PF03946.9 EGC33240.1 - 3.3e-18 64.8 0.1 5.5e-18 64.1 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein L11, N-terminal domain Ribosomal_L11 PF00298.14 EGC33240.1 - 6.4e-11 42.2 0.3 1.2e-10 41.3 0.1 1.6 2 0 0 2 2 2 1 Ribosomal protein L11, RNA binding domain SOR_SNZ PF01680.12 EGC33241.1 - 1.9e-113 377.2 7.5 1.9e-113 377.2 5.2 1.5 2 0 0 2 2 2 1 SOR/SNZ family ThiG PF05690.9 EGC33241.1 - 7.2e-08 31.7 7.8 4e-07 29.3 0.2 2.7 2 1 1 3 3 3 2 Thiazole biosynthesis protein ThiG Dus PF01207.12 EGC33241.1 - 0.00011 21.1 0.3 0.017 13.9 0.1 2.4 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) IGPS PF00218.16 EGC33241.1 - 0.0003 19.9 0.1 0.013 14.5 0.0 2.4 2 0 0 2 2 2 1 Indole-3-glycerol phosphate synthase NanE PF04131.9 EGC33241.1 - 0.00039 19.4 1.5 0.018 13.9 0.0 3.1 2 2 0 2 2 2 1 Putative N-acetylmannosamine-6-phosphate epimerase His_biosynth PF00977.16 EGC33241.1 - 0.0007 18.9 1.0 0.063 12.5 0.0 2.9 2 1 1 3 3 3 1 Histidine biosynthesis protein NMO PF03060.10 EGC33241.1 - 0.0048 16.0 0.2 0.0048 16.0 0.1 2.3 2 1 0 2 2 2 1 Nitronate monooxygenase FMN_dh PF01070.13 EGC33241.1 - 0.009 14.8 0.2 0.033 13.0 0.0 1.9 2 0 0 2 2 2 1 FMN-dependent dehydrogenase SLBP_RNA_bind PF15247.1 EGC33242.1 - 1.4e-31 108.1 2.7 1.4e-31 108.1 1.8 2.5 2 0 0 2 2 2 1 Histone RNA hairpin-binding protein RNA-binding domain MORN PF02493.15 EGC33243.1 - 1.7e-09 36.8 27.0 0.042 13.5 1.1 5.8 6 0 0 6 6 6 5 MORN repeat SET PF00856.23 EGC33243.1 - 2.8e-05 24.4 1.2 0.0012 19.1 0.0 3.0 2 1 0 2 2 2 1 SET domain Pkinase_Tyr PF07714.12 EGC33244.1 - 6.4e-53 179.4 0.0 1.1e-52 178.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC33244.1 - 1.7e-46 158.4 0.0 3.3e-46 157.5 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Miro PF08477.8 EGC33244.1 - 3.7e-16 59.7 1.1 9.3e-15 55.1 0.0 2.7 2 0 0 2 2 2 1 Miro-like protein Ras PF00071.17 EGC33244.1 - 7.5e-14 51.4 2.2 6.4e-13 48.4 0.2 2.4 2 0 0 2 2 2 1 Ras family LRR_4 PF12799.2 EGC33244.1 - 9e-09 34.7 12.4 5.6e-06 25.8 1.1 3.0 1 1 2 3 3 3 3 Leucine Rich repeats (2 copies) Arf PF00025.16 EGC33244.1 - 4.2e-08 32.6 0.1 8.9e-08 31.5 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family LRR_8 PF13855.1 EGC33244.1 - 7.1e-07 28.8 5.0 2.9e-06 26.9 1.2 2.9 1 1 1 2 2 2 2 Leucine rich repeat WD40 PF00400.27 EGC33244.1 - 9.4e-07 28.4 8.5 0.00031 20.5 0.0 4.7 4 0 0 4 4 4 1 WD domain, G-beta repeat LRR_1 PF00560.28 EGC33244.1 - 0.00025 20.6 10.4 0.27 11.4 0.1 4.8 4 0 0 4 4 3 2 Leucine Rich Repeat PduV-EutP PF10662.4 EGC33244.1 - 0.00057 19.4 0.3 0.0015 18.0 0.2 1.7 1 0 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation DUF258 PF03193.11 EGC33244.1 - 0.01 15.0 0.3 0.032 13.4 0.2 1.8 1 0 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGC33244.1 - 0.012 14.8 0.1 0.012 14.8 0.0 2.9 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region SRP54 PF00448.17 EGC33244.1 - 0.062 12.7 0.4 1.1 8.7 0.2 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain LRR_7 PF13504.1 EGC33244.1 - 0.1 12.8 2.1 7.9 7.1 0.0 4.4 3 0 0 3 3 3 0 Leucine rich repeat Cbl_N PF02262.11 EGC33245.1 - 0.096 12.3 0.2 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 CBL proto-oncogene N-terminal domain 1 SnoaL_2 PF12680.2 EGC33246.1 - 2e-05 24.9 0.0 2.3e-05 24.7 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGC33246.1 - 0.014 14.9 0.1 0.028 13.9 0.1 1.6 1 1 0 1 1 1 0 SnoaL-like polyketide cyclase DUF3271 PF11675.3 EGC33246.1 - 0.019 14.1 0.1 0.023 13.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DUF4440 PF14534.1 EGC33246.1 - 0.038 14.2 0.0 0.045 13.9 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) HopJ PF08888.6 EGC33246.1 - 0.039 13.9 0.0 0.054 13.4 0.0 1.4 1 0 0 1 1 1 0 HopJ type III effector protein KGK PF08872.5 EGC33246.1 - 0.073 13.2 0.2 0.089 12.9 0.1 1.2 1 0 0 1 1 1 0 KGK domain TFIIS_C PF01096.13 EGC33247.1 - 4.7e-08 32.5 0.3 4.7e-08 32.5 0.2 2.7 3 0 0 3 3 3 1 Transcription factor S-II (TFIIS) RNA_POL_M_15KD PF02150.11 EGC33247.1 - 7.4e-07 28.7 4.5 7.9e-07 28.6 0.7 2.3 2 0 0 2 2 2 1 RNA polymerases M/15 Kd subunit Elf1 PF05129.8 EGC33247.1 - 0.025 14.2 5.7 0.081 12.6 0.2 2.3 2 1 0 2 2 2 0 Transcription elongation factor Elf1 like zf-DNA_Pol PF08996.5 EGC33247.1 - 0.052 12.8 1.5 0.081 12.2 0.1 1.8 1 1 1 2 2 2 0 DNA Polymerase alpha zinc finger C1_1 PF00130.17 EGC33247.1 - 0.085 12.5 0.1 0.085 12.5 0.1 2.3 3 0 0 3 3 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) Zn_Tnp_IS1595 PF12760.2 EGC33247.1 - 0.14 11.9 6.4 1.2 8.9 1.3 2.5 2 1 0 2 2 2 0 Transposase zinc-ribbon domain IBR PF01485.16 EGC33247.1 - 0.16 11.9 6.0 1.4 8.8 1.5 2.9 2 1 0 2 2 2 0 IBR domain RPA_interact_C PF14768.1 EGC33247.1 - 0.16 12.4 4.9 0.52 10.7 0.2 2.3 2 1 0 2 2 2 0 Replication protein A interacting C-terminal DZR PF12773.2 EGC33247.1 - 0.21 11.4 6.4 1.2 9.0 1.9 2.6 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_6 PF14835.1 EGC33247.1 - 0.31 10.8 1.7 1.1 9.1 0.0 2.4 2 1 0 2 2 2 0 zf-RING of BARD1-type protein zf-Mss51 PF13824.1 EGC33247.1 - 0.32 10.8 4.5 2.8 7.8 0.4 2.4 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 zinc_ribbon_5 PF13719.1 EGC33247.1 - 0.35 10.4 8.4 4.5 6.9 0.2 3.7 4 0 0 4 4 4 0 zinc-ribbon domain Trm112p PF03966.11 EGC33247.1 - 0.87 9.9 5.9 0.67 10.3 0.8 2.5 2 2 0 2 2 2 0 Trm112p-like protein zinc-ribbons_6 PF07191.7 EGC33247.1 - 0.95 9.2 5.2 2.4 7.9 0.1 2.6 3 0 0 3 3 3 0 zinc-ribbons zf-Di19 PF05605.7 EGC33247.1 - 1.5 8.9 7.5 7.1 6.8 0.1 3.1 2 1 1 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding PHD PF00628.24 EGC33247.1 - 1.8 8.3 6.4 0.42 10.3 0.2 2.6 2 1 0 2 2 2 0 PHD-finger Ribosomal_S27e PF01667.12 EGC33247.1 - 2 8.0 6.8 25 4.4 0.1 3.3 3 1 0 3 3 3 0 Ribosomal protein S27 zinc_ribbon_4 PF13717.1 EGC33247.1 - 2.5 7.8 11.5 5.6 6.7 0.3 3.6 4 0 0 4 4 4 0 zinc-ribbon domain Nudix_N_2 PF14803.1 EGC33247.1 - 6.8 6.4 7.5 1.3 8.7 0.9 2.7 2 1 0 2 2 2 0 Nudix N-terminal zf-H2C2_2 PF13465.1 EGC33247.1 - 7.3 7.0 9.6 13 6.2 0.5 3.3 3 0 0 3 3 3 0 Zinc-finger double domain Glyco_transf_20 PF00982.16 EGC33248.1 - 5.1e-181 602.2 0.0 8.2e-181 601.6 0.0 1.3 2 0 0 2 2 2 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGC33248.1 - 7.3e-40 136.3 0.0 1.7e-39 135.1 0.0 1.7 2 0 0 2 2 2 1 Trehalose-phosphatase Glycos_transf_1 PF00534.15 EGC33248.1 - 5.3e-06 25.9 0.4 6e-05 22.5 0.3 2.5 1 1 0 1 1 1 1 Glycosyl transferases group 1 DUF2120 PF09893.4 EGC33248.1 - 0.091 12.7 0.1 0.3 11.0 0.0 2.0 1 1 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) HalX PF08663.5 EGC33248.1 - 0.11 12.4 0.0 0.8 9.7 0.0 2.2 2 0 0 2 2 2 0 HalX domain TPR_11 PF13414.1 EGC33249.1 - 1.9e-30 104.2 15.9 1.2e-09 37.6 3.1 6.4 3 2 2 6 6 6 5 TPR repeat TPR_1 PF00515.23 EGC33249.1 - 1.1e-29 100.7 28.1 4.1e-08 32.5 0.5 9.0 9 0 0 9 9 9 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGC33249.1 - 2.6e-29 98.7 21.7 7.3e-07 28.6 0.1 9.0 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_8 PF13181.1 EGC33249.1 - 6.4e-24 81.9 13.8 4e-08 32.4 0.1 7.6 7 0 0 7 7 7 4 Tetratricopeptide repeat Apc3 PF12895.2 EGC33249.1 - 7.1e-21 74.1 31.0 6.2e-11 42.2 1.8 5.8 4 2 2 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGC33249.1 - 1.1e-19 70.5 0.2 8.7e-09 35.8 0.3 4.8 6 0 0 6 6 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC33249.1 - 2.7e-19 68.8 12.5 8.3e-05 22.4 0.2 6.5 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGC33249.1 - 1.6e-14 53.0 0.2 0.0051 17.3 0.0 7.5 5 2 3 8 8 8 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGC33249.1 - 6.6e-14 51.3 12.7 0.05 14.0 0.0 8.5 8 0 0 8 8 8 4 Tetratricopeptide repeat TPR_19 PF14559.1 EGC33249.1 - 4.8e-13 49.2 9.5 6.6e-06 26.3 0.5 6.2 5 2 1 7 7 6 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGC33249.1 - 5.3e-13 48.0 21.6 0.24 11.7 0.1 10.1 10 0 0 10 10 10 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGC33249.1 - 5.2e-06 26.2 0.3 0.43 10.4 0.1 3.7 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC33249.1 - 1.6e-05 24.3 1.3 0.038 13.7 0.0 4.4 5 0 0 5 5 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGC33249.1 - 4.8e-05 22.5 3.6 0.0041 16.2 0.0 3.4 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGC33249.1 - 0.0011 19.0 2.5 0.0065 16.5 0.0 3.4 4 0 0 4 4 3 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC33249.1 - 0.0024 17.6 6.2 0.088 12.7 0.0 4.4 4 0 0 4 4 4 1 Fis1 C-terminal tetratricopeptide repeat TPR_10 PF13374.1 EGC33249.1 - 0.011 15.6 6.2 2.6 8.1 0.1 4.7 6 0 0 6 6 5 0 Tetratricopeptide repeat WD40 PF00400.27 EGC33250.1 - 1.1e-09 37.7 21.0 1.7e-06 27.7 0.2 5.4 6 0 0 6 6 6 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC33250.1 - 0.038 13.7 0.3 7.2 6.4 0.0 3.6 3 1 1 4 4 4 0 Ciliary BBSome complex subunit 2, middle region adh_short PF00106.20 EGC33251.1 - 2.7e-19 69.6 0.0 3.7e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC33251.1 - 3.4e-09 36.8 0.0 4.5e-09 36.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC33251.1 - 6.1e-07 29.2 0.0 1.3e-06 28.1 0.0 1.5 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC33251.1 - 0.019 14.0 0.0 0.03 13.4 0.0 1.3 1 0 0 1 1 1 0 Fungal family of unknown function (DUF1776) DUF554 PF04474.7 EGC33251.1 - 0.049 12.7 0.0 0.076 12.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF554) CDO_I PF05995.7 EGC33252.1 - 1.5e-27 95.9 0.0 1.9e-27 95.5 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I DUF1637 PF07847.7 EGC33252.1 - 0.053 12.8 0.0 0.066 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1637) FNIP PF05725.7 EGC33253.1 - 1e-20 73.3 71.3 0.00032 20.5 0.5 12.6 7 5 4 12 12 12 12 FNIP Repeat AAA_22 PF13401.1 EGC33254.1 - 1.3e-07 31.8 0.2 8.8e-07 29.1 0.1 2.4 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC33254.1 - 0.0063 16.5 0.0 0.016 15.1 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_28 PF13521.1 EGC33254.1 - 0.019 14.9 0.2 0.035 14.0 0.1 1.4 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGC33254.1 - 0.025 14.7 3.6 0.062 13.4 1.1 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC33254.1 - 0.026 15.3 0.0 0.026 15.3 0.0 3.8 5 1 0 5 5 5 0 AAA domain AAA_25 PF13481.1 EGC33254.1 - 0.18 11.1 0.0 0.4 10.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain zf-MYND PF01753.13 EGC33255.1 - 2.8e-08 33.5 11.9 4.7e-08 32.7 8.2 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EGC33255.1 - 0.011 15.5 3.9 0.011 15.5 2.7 1.9 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 FYVE_2 PF02318.11 EGC33255.1 - 0.57 10.0 10.1 0.047 13.5 3.1 2.0 1 1 0 2 2 2 0 FYVE-type zinc finger Vault PF01505.13 EGC33256.1 - 3.1e-42 142.3 0.1 3e-12 46.3 0.0 6.0 6 0 0 6 6 6 5 Major Vault Protein repeat DUF3601 PF12208.3 EGC33256.1 - 0.00033 20.5 0.0 0.041 13.8 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF3601) tRNA-synt_1d PF00750.14 EGC33256.1 - 0.047 12.4 0.0 0.071 11.9 0.0 1.3 1 0 0 1 1 1 0 tRNA synthetases class I (R) DUF3430 PF11912.3 EGC33257.1 - 9.6e-08 32.1 33.9 3.5e-07 30.2 23.5 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) GST_N PF02798.15 EGC33258.1 - 5.5e-08 32.8 0.0 1.1e-07 31.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC33258.1 - 3.6e-07 30.0 0.0 6e-07 29.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC33258.1 - 6.6e-07 29.4 0.0 1.1e-06 28.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC33258.1 - 0.00014 22.2 0.0 0.00021 21.7 0.0 1.4 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC33258.1 - 0.00061 19.6 0.0 0.0029 17.4 0.0 2.0 2 1 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC33258.1 - 0.11 12.5 0.0 0.19 11.7 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, N-terminal domain PaaSYMP PF14738.1 EGC33259.1 - 0.0022 17.7 3.3 0.038 13.7 1.2 2.1 2 0 0 2 2 2 2 Solute carrier (proton/amino acid symporter), TRAMD3 or PAT1 DUF4119 PF13494.1 EGC33259.1 - 0.45 10.5 3.6 0.88 9.5 2.5 1.5 1 1 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF4119) Pkinase PF00069.20 EGC33260.1 - 5.9e-72 241.9 0.0 7e-72 241.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33260.1 - 1.6e-39 135.5 0.0 2e-39 135.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33260.1 - 4.5e-05 22.5 0.0 0.0017 17.3 0.0 2.1 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EGC33260.1 - 7.2e-05 21.9 0.1 0.00016 20.8 0.0 1.5 1 1 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC33260.1 - 0.01 15.1 0.0 0.015 14.6 0.0 1.2 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Ada3 PF10198.4 EGC33261.1 - 4.7e-09 36.0 11.2 4.7e-09 36.0 7.8 3.6 3 1 0 4 4 4 1 Histone acetyltransferases subunit 3 DUF3379 PF11859.3 EGC33262.1 - 0.0041 16.3 0.1 0.0041 16.3 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3379) NYD-SP28 PF14772.1 EGC33262.1 - 0.051 13.6 0.0 0.056 13.5 0.0 1.0 1 0 0 1 1 1 0 Sperm tail Tubulin_C PF03953.12 EGC33262.1 - 0.076 13.0 0.0 0.079 13.0 0.0 1.0 1 0 0 1 1 1 0 Tubulin C-terminal domain 2_5_RNA_ligase2 PF13563.1 EGC33263.1 - 5.2e-19 68.4 0.0 6.1e-19 68.2 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily AKAP7_NLS PF10469.4 EGC33263.1 - 1.4e-06 28.1 0.1 1.8e-06 27.8 0.1 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain LigT_PEase PF02834.11 EGC33263.1 - 8e-06 25.7 0.0 0.002 18.0 0.0 2.2 2 0 0 2 2 2 2 LigT like Phosphoesterase CPDase PF07823.6 EGC33263.1 - 0.0025 17.3 0.0 0.0033 16.9 0.0 1.3 1 0 0 1 1 1 1 Cyclic phosphodiesterase-like protein DUF1877 PF08974.5 EGC33263.1 - 0.13 11.9 0.1 0.13 11.9 0.1 1.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1877) F5_F8_type_C PF00754.20 EGC33264.1 - 1.9e-23 82.6 1.8 1.9e-23 82.6 1.3 1.6 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC33264.1 - 4.4e-21 74.3 0.1 1e-20 73.1 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain YqfD PF06898.6 EGC33265.1 - 0.017 13.8 0.2 0.029 13.0 0.2 1.3 1 0 0 1 1 1 0 Putative stage IV sporulation protein YqfD CTD_bind PF04818.8 EGC33266.1 - 2e-06 27.9 2.4 3.4e-06 27.1 0.2 2.7 2 0 0 2 2 2 1 RNA polymerase II-binding domain. Dimer_Tnp_hAT PF05699.9 EGC33267.1 - 1.2e-08 34.4 1.2 1.7e-08 33.9 0.8 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region RPEL PF02755.10 EGC33267.1 - 0.082 12.2 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 RPEL repeat Staph_haemo PF05480.6 EGC33267.1 - 0.11 12.1 0.4 0.26 11.0 0.3 1.6 1 0 0 1 1 1 0 Staphylococcus haemolytic protein DUF1972 PF09314.6 EGC33267.1 - 0.21 11.0 1.6 0.4 10.1 0.1 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1972) SNF2_N PF00176.18 EGC33268.1 - 1.3e-53 181.7 0.3 3e-53 180.5 0.2 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC33268.1 - 1.1e-10 41.2 0.1 6.7e-10 38.6 0.0 2.5 3 0 0 3 3 3 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EGC33268.1 - 0.0053 16.3 13.5 0.015 14.9 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33268.1 - 0.025 14.6 9.6 0.12 12.3 6.8 2.2 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC33268.1 - 0.05 13.2 10.7 0.14 11.8 7.4 1.8 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) DUF1736 PF08409.6 EGC33268.1 - 0.091 12.3 0.0 0.21 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1736) zf-RING_5 PF14634.1 EGC33268.1 - 1 9.1 12.0 5.8 6.7 8.4 2.3 1 1 0 1 1 1 0 zinc-RING finger domain TPR_12 PF13424.1 EGC33269.1 - 4.4e-06 26.5 2.1 0.23 11.4 0.0 4.2 3 2 1 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC33269.1 - 5e-05 22.8 1.4 0.024 14.2 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_2 PF07719.12 EGC33269.1 - 0.00014 21.5 0.6 0.13 12.2 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC33269.1 - 0.0025 17.3 2.2 0.29 10.8 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC33269.1 - 0.058 14.0 0.0 9.4 7.0 0.0 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC33269.1 - 0.1 12.5 0.1 0.62 10.0 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat Asp-B-Hydro_N PF05279.6 EGC33269.1 - 0.17 11.6 41.9 0.45 10.3 29.1 1.8 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region PPR PF01535.15 EGC33269.1 - 0.21 11.6 2.0 6.2 7.0 0.0 3.7 4 0 0 4 4 4 0 PPR repeat CDC27 PF09507.5 EGC33269.1 - 0.28 10.3 50.0 0.92 8.6 0.2 2.2 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 TPR_8 PF13181.1 EGC33269.1 - 2 8.3 0.0 2 8.3 0.0 5.7 5 1 1 6 6 6 0 Tetratricopeptide repeat SprA-related PF12118.3 EGC33269.1 - 7.7 5.7 35.1 0.095 12.0 19.2 1.6 2 0 0 2 2 2 0 SprA-related family EGF_2 PF07974.8 EGC33270.1 - 0.033 14.3 12.1 0.07 13.3 8.4 1.6 1 0 0 1 1 1 0 EGF-like domain PrgI PF12666.2 EGC33271.1 - 0.16 12.1 2.3 0.17 12.0 1.6 1.1 1 0 0 1 1 1 0 PrgI family protein DUF4328 PF14219.1 EGC33271.1 - 0.28 10.4 2.4 0.31 10.3 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4328) RseC_MucC PF04246.7 EGC33271.1 - 1.2 8.7 3.7 1.3 8.6 2.6 1.1 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC CcoS PF03597.10 EGC33271.1 - 1.4 8.4 8.7 0.084 12.3 1.0 2.0 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type DUF1469 PF07332.6 EGC33271.1 - 3.4 7.4 7.5 3.7 7.2 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1469) HMG_box PF00505.14 EGC33272.1 - 2.7e-19 69.1 2.2 2.7e-19 69.1 1.5 3.7 3 0 0 3 3 3 1 HMG (high mobility group) box PHD PF00628.24 EGC33272.1 - 3e-19 68.4 53.6 2e-11 43.3 4.5 5.1 3 1 2 5 5 5 3 PHD-finger HMG_box_2 PF09011.5 EGC33272.1 - 1.3e-16 60.7 0.9 1.3e-16 60.7 0.6 4.3 5 1 0 5 5 5 1 HMG-box domain C1_1 PF00130.17 EGC33272.1 - 0.00053 19.6 4.8 0.00053 19.6 3.3 5.7 3 1 3 6 6 6 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Thioredoxin PF00085.15 EGC33273.1 - 0.00035 20.1 0.0 0.0012 18.4 0.0 2.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EGC33273.1 - 0.0017 17.8 0.7 0.0048 16.4 0.1 2.1 1 1 1 2 2 2 1 Thioredoxin DDE_Tnp_ISAZ013 PF07592.6 EGC33273.1 - 0.0042 15.8 6.9 0.0068 15.1 4.8 1.3 1 0 0 1 1 1 1 Rhodopirellula transposase DDE domain DUF2201_N PF13203.1 EGC33273.1 - 0.13 11.3 4.2 0.2 10.8 2.9 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain FLO_LFY PF01698.11 EGC33273.1 - 0.4 9.4 10.7 0.039 12.8 2.3 2.0 2 0 0 2 2 2 0 Floricaula / Leafy protein DUF2626 PF11117.3 EGC33273.1 - 1 9.8 5.9 0.69 10.3 0.6 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2626) AAA_18 PF13238.1 EGC33273.1 - 2.6 8.3 9.6 2.3 8.5 1.9 2.3 2 0 0 2 2 2 0 AAA domain Sec62 PF03839.11 EGC33273.1 - 5.8 6.2 11.6 1.6 8.0 4.4 2.2 2 0 0 2 2 2 0 Translocation protein Sec62 Dala_Dala_lig_N PF01820.16 EGC33273.1 - 9 6.6 6.9 9.3 6.5 2.6 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Pkinase PF00069.20 EGC33274.1 - 5.8e-77 258.3 0.0 1.1e-76 257.4 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33274.1 - 6.8e-44 149.8 0.0 1.2e-43 149.0 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase KA1 PF02149.14 EGC33274.1 - 8.9e-19 66.6 0.0 1.6e-18 65.8 0.0 1.5 1 0 0 1 1 1 1 Kinase associated domain 1 Kinase-like PF14531.1 EGC33274.1 - 5e-05 22.4 0.0 9.2e-05 21.5 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC33274.1 - 0.0046 16.0 0.0 0.012 14.6 0.0 1.7 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC33274.1 - 0.007 16.1 0.0 0.11 12.1 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family Spore_YpjB PF09577.5 EGC33274.1 - 0.024 14.2 0.5 0.054 13.0 0.3 1.5 1 0 0 1 1 1 0 Sporulation protein YpjB (SpoYpjB) LRR_4 PF12799.2 EGC33275.1 - 4.2e-48 160.2 92.9 1.5e-08 34.0 1.3 8.1 2 2 9 11 11 11 11 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC33275.1 - 4.7e-47 157.5 68.2 9.7e-10 38.0 2.5 6.3 1 1 6 7 7 7 7 Leucine rich repeat LRR_1 PF00560.28 EGC33275.1 - 5.1e-27 89.7 46.2 0.0051 16.6 0.2 13.4 13 0 0 13 13 13 10 Leucine Rich Repeat LRR_7 PF13504.1 EGC33275.1 - 7.6e-21 70.5 43.6 0.02 14.9 0.4 13.3 13 0 0 13 13 13 7 Leucine rich repeat LRR_6 PF13516.1 EGC33275.1 - 3.3e-09 35.8 44.1 0.018 15.0 0.0 12.4 13 0 0 13 13 13 3 Leucine Rich repeat LRR_9 PF14580.1 EGC33275.1 - 0.0019 17.7 15.6 0.35 10.4 0.4 4.4 1 1 3 4 4 4 2 Leucine-rich repeat LRR_2 PF07723.8 EGC33275.1 - 9.7 6.8 17.3 10 6.7 0.1 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat RasGEF PF00617.14 EGC33276.1 - 2.7e-59 200.0 1.1 2.7e-59 200.0 0.8 1.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC33276.1 - 1.1e-15 57.6 5.4 3.2e-15 56.1 0.0 4.2 3 0 0 3 3 3 1 RasGEF N-terminal motif Drf_GBD PF06371.8 EGC33276.1 - 3.1e-13 49.4 5.0 3.1e-13 49.4 3.4 3.1 2 1 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGC33276.1 - 4.3e-05 23.0 22.5 4.3e-05 23.0 15.6 3.0 2 1 0 2 2 2 1 Diaphanous FH3 Domain FERM_N PF09379.5 EGC33276.1 - 8.5e-05 22.5 0.2 0.31 11.1 0.0 3.9 3 0 0 3 3 3 2 FERM N-terminal domain GCFC PF07842.7 EGC33277.1 - 1.1e-49 169.2 13.7 1.1e-49 169.2 9.5 2.1 3 0 0 3 3 3 1 GC-rich sequence DNA-binding factor-like protein TIP_N PF12457.3 EGC33277.1 - 7.6e-11 42.0 15.5 7.6e-11 42.0 10.7 4.1 2 2 2 4 4 4 1 Tuftelin interacting protein N terminal G-patch PF01585.18 EGC33277.1 - 1.5e-09 37.4 3.6 3.8e-09 36.1 2.5 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGC33277.1 - 7.4e-06 25.7 1.9 7.4e-06 25.7 1.3 4.1 3 1 2 5 5 5 1 DExH-box splicing factor binding site HTH_3 PF01381.17 EGC33278.1 - 1.7e-15 56.5 0.1 4e-15 55.3 0.0 1.6 2 0 0 2 2 2 1 Helix-turn-helix HTH_19 PF12844.2 EGC33278.1 - 1e-07 31.9 0.1 2e-07 30.9 0.0 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_31 PF13560.1 EGC33278.1 - 0.00031 20.8 0.0 0.00048 20.2 0.0 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain Jag_N PF14804.1 EGC33278.1 - 0.034 14.1 0.0 0.087 12.8 0.0 1.7 1 1 1 2 2 2 0 Jag N-terminus HTH_37 PF13744.1 EGC33278.1 - 0.044 13.6 0.3 0.073 12.8 0.1 1.4 2 0 0 2 2 2 0 Helix-turn-helix domain FlaG PF03646.10 EGC33278.1 - 0.059 13.5 0.1 0.091 12.9 0.1 1.3 1 0 0 1 1 1 0 FlaG protein DPM2 PF07297.7 EGC33280.1 - 4.1e-30 103.8 7.2 4.5e-30 103.7 5.0 1.0 1 0 0 1 1 1 1 Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) PIG-P PF08510.7 EGC33280.1 - 6.8e-05 22.5 6.5 8e-05 22.2 4.5 1.0 1 0 0 1 1 1 1 PIG-P Ferric_reduct PF01794.14 EGC33280.1 - 0.18 11.8 3.5 0.22 11.5 2.4 1.1 1 0 0 1 1 1 0 Ferric reductase like transmembrane component DUF2842 PF11003.3 EGC33280.1 - 0.27 11.1 6.2 0.25 11.2 0.8 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2842) DUF1700 PF08006.6 EGC33280.1 - 1 8.6 6.0 1.3 8.2 4.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) zf-DHHC PF01529.15 EGC33280.1 - 3.4 7.0 4.8 4.1 6.7 3.4 1.1 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF1049 PF06305.6 EGC33280.1 - 4 6.9 9.4 3.3 7.2 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1625 PF07787.7 EGC33280.1 - 8.4 5.5 6.3 9.8 5.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1625) PCI_Csn8 PF10075.4 EGC33281.1 - 3.5e-24 85.2 0.7 5.8e-24 84.5 0.5 1.3 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 SAC3_GANP PF03399.11 EGC33281.1 - 6.1e-24 84.7 1.9 8.6e-24 84.2 1.3 1.2 1 0 0 1 1 1 1 SAC3/GANP/Nin1/mts3/eIF-3 p25 family DUF3605 PF12239.3 EGC33281.1 - 0.01 15.6 0.7 0.017 14.9 0.5 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3605) DUF2410 PF10307.4 EGC33281.1 - 0.033 13.5 0.8 0.09 12.1 0.1 2.0 2 1 0 2 2 2 0 Hypothetical protein (DUF2410) zf-C3HC4_3 PF13920.1 EGC33284.1 - 5.9e-13 48.2 11.6 1.1e-12 47.3 8.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) SH2 PF00017.19 EGC33284.1 - 9.4e-08 31.7 0.0 3.4e-07 29.9 0.0 2.1 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.9 EGC33284.1 - 7.3e-05 22.7 0.5 0.00017 21.5 0.4 1.6 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain zf-C3HC4_2 PF13923.1 EGC33284.1 - 0.0001 22.2 15.0 0.00025 20.9 10.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cbl_N3 PF02762.9 EGC33284.1 - 0.064 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, SH2-like domain Prok-RING_4 PF14447.1 EGC33284.1 - 0.35 10.4 7.2 1 8.9 5.0 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_2 PF13639.1 EGC33284.1 - 0.56 10.0 12.3 1 9.2 8.5 1.5 1 0 0 1 1 1 0 Ring finger domain zf-RING_5 PF14634.1 EGC33284.1 - 0.73 9.6 13.2 1.8 8.3 9.1 1.7 1 0 0 1 1 1 0 zinc-RING finger domain p450 PF00067.17 EGC33285.1 - 2e-68 231.0 0.0 2.3e-68 230.7 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGC33286.1 - 1.6e-64 218.1 0.0 1.8e-64 217.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1009 PF06230.6 EGC33286.1 - 0.025 13.9 0.0 0.045 13.1 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1009) DUF4163 PF13739.1 EGC33286.1 - 0.21 12.3 2.4 5.9 7.7 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4163) p450 PF00067.17 EGC33287.1 - 7.3e-75 252.2 0.2 8.5e-75 252.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 HOK_GEF PF01848.11 EGC33287.1 - 0.46 9.8 2.4 0.91 8.9 1.7 1.4 1 0 0 1 1 1 0 Hok/gef family Methyltransf_7 PF03492.10 EGC33288.1 - 5e-18 64.9 5.6 2.4e-17 62.7 3.9 1.8 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.7 EGC33288.1 - 0.013 15.9 0.1 0.13 12.7 0.0 2.7 2 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC33288.1 - 0.034 13.8 0.0 0.082 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_31 PF13847.1 EGC33288.1 - 0.053 13.0 0.2 13 5.3 0.0 2.9 1 1 0 2 2 2 0 Methyltransferase domain Clat_adaptor_s PF01217.15 EGC33289.1 - 5.1e-54 181.8 1.1 5.8e-54 181.6 0.7 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DUF1204 PF06721.6 EGC33289.1 - 0.02 14.1 0.0 0.028 13.6 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1204) tRNA_int_endo PF01974.12 EGC33290.1 - 1e-20 73.3 0.1 2.8e-20 71.9 0.1 1.8 1 0 0 1 1 1 1 tRNA intron endonuclease, catalytic C-terminal domain Mem_trans PF03547.13 EGC33290.1 - 0.016 13.5 1.5 0.02 13.2 1.0 1.1 1 0 0 1 1 1 0 Membrane transport protein EF-hand_7 PF13499.1 EGC33291.1 - 2.7e-20 72.2 8.9 8.8e-12 44.9 0.4 3.1 1 1 2 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC33291.1 - 3.3e-18 63.5 5.5 0.00054 19.0 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC33291.1 - 1.7e-17 61.6 3.8 0.0011 18.7 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain SPARC_Ca_bdg PF10591.4 EGC33291.1 - 1.9e-07 31.1 3.4 0.0039 17.1 1.2 2.7 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 EGC33291.1 - 1.5e-06 27.2 2.8 4.1 6.9 0.0 4.5 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC33291.1 - 0.00053 19.5 7.4 1.6 8.4 0.0 4.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_like PF09279.6 EGC33291.1 - 0.001 19.0 2.0 1.5 8.9 0.7 3.1 1 1 0 2 2 2 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_10 PF14788.1 EGC33291.1 - 0.0028 17.2 1.7 5.6 6.7 0.0 3.2 3 0 0 3 3 3 2 EF hand Dimerisation PF08100.6 EGC33291.1 - 0.0032 17.2 0.1 2.5 8.0 0.0 3.2 2 1 1 3 3 3 1 Dimerisation domain Latarcin PF10279.4 EGC33291.1 - 0.022 14.9 0.0 0.05 13.7 0.0 1.8 1 1 0 1 1 1 0 Latarcin precursor DUF2624 PF11116.3 EGC33291.1 - 0.14 12.6 2.5 0.25 11.8 0.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) DUF4007 PF13182.1 EGC33291.1 - 0.18 10.6 3.1 0.17 10.7 0.9 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF4007) KIP1 PF07765.7 EGC33291.1 - 0.19 11.5 7.9 2.5 7.9 0.3 3.1 1 1 1 3 3 3 0 KIP1-like protein PhoQ_Sensor PF08918.5 EGC33291.1 - 0.2 11.1 1.2 0.66 9.4 0.0 2.0 1 1 1 2 2 2 0 PhoQ Sensor NCD2 PF04905.8 EGC33291.1 - 0.61 9.8 3.2 1.4 8.7 0.2 2.4 1 1 1 2 2 2 0 NAB conserved region 2 (NCD2) Ribosomal_L15e PF00827.12 EGC33292.1 - 3.7e-94 313.6 9.0 4.3e-94 313.4 6.2 1.0 1 0 0 1 1 1 1 Ribosomal L15 SRP14 PF02290.10 EGC33293.1 - 5.3e-25 87.1 1.2 5.3e-25 87.1 0.9 1.5 2 0 0 2 2 2 1 Signal recognition particle 14kD protein DUF365 PF04033.7 EGC33293.1 - 0.1 12.5 0.8 0.4 10.6 0.0 2.0 1 1 0 2 2 2 0 Domain of unknown function (DUF365) RNase_PH PF01138.16 EGC33294.1 - 5.4e-20 72.0 0.0 9.6e-20 71.2 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGC33294.1 - 6.3e-10 38.8 0.0 1.3e-09 37.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 zf-TRAF PF02176.13 EGC33296.1 - 3.2e-10 40.2 35.7 1.8e-05 25.0 2.0 4.5 3 2 1 4 4 4 3 TRAF-type zinc finger MATH PF00917.21 EGC33296.1 - 0.00011 22.3 3.4 0.00011 22.3 2.4 2.4 2 1 0 2 2 2 1 MATH domain Sina PF03145.11 EGC33296.1 - 0.00064 19.4 3.3 0.00064 19.4 2.3 3.6 1 1 3 4 4 4 1 Seven in absentia protein family Med11 PF10280.4 EGC33296.1 - 0.0054 16.7 0.0 0.0087 16.1 0.0 1.4 1 0 0 1 1 1 1 Mediator complex protein DM PF00751.13 EGC33296.1 - 0.017 14.6 4.7 0.017 14.6 3.3 4.4 3 1 3 6 6 6 0 DM DNA binding domain zf-Di19 PF05605.7 EGC33296.1 - 0.46 10.6 11.2 2.5 8.2 0.1 3.2 2 1 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding SF3b10 PF07189.6 EGC33297.1 - 0.073 12.9 1.4 1.2 9.0 0.0 2.9 3 0 0 3 3 3 0 Splicing factor 3B subunit 10 (SF3b10) RGS PF00615.14 EGC33298.1 - 7.5e-28 97.0 5.2 7.5e-28 97.0 3.6 3.9 4 0 0 4 4 4 1 Regulator of G protein signaling domain Peptidase_M48 PF01435.13 EGC33299.1 - 3.7e-09 36.4 0.0 6.1e-09 35.7 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M48 Pyr_redox_2 PF07992.9 EGC33299.1 - 4.9e-07 29.8 0.0 1.3e-06 28.4 0.0 1.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC33299.1 - 1.3e-06 28.5 0.0 0.0027 17.8 0.0 2.8 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC33299.1 - 1.1e-05 25.3 0.0 2.3e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_7 PF13241.1 EGC33299.1 - 0.0029 17.8 0.0 0.52 10.6 0.0 2.5 2 0 0 2 2 2 1 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGC33299.1 - 0.016 14.9 0.0 0.25 11.1 0.0 2.5 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox PF00070.22 EGC33299.1 - 0.017 15.5 0.0 3.4 8.1 0.0 3.0 2 1 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC33299.1 - 0.037 12.9 0.1 0.74 8.6 0.0 2.2 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGC33299.1 - 0.1 11.0 0.0 0.18 10.2 0.0 1.3 1 0 0 1 1 1 0 HI0933-like protein Lycopene_cycl PF05834.7 EGC33299.1 - 0.1 11.4 0.0 0.16 10.8 0.0 1.2 1 0 0 1 1 1 0 Lycopene cyclase protein Mit_ribos_Mrp51 PF11709.3 EGC33299.1 - 0.13 11.4 0.5 0.29 10.3 0.4 1.5 1 0 0 1 1 1 0 Mitochondrial ribosomal protein subunit ELFV_dehydrog PF00208.16 EGC33299.1 - 0.17 11.4 0.4 1.5 8.3 0.0 2.4 3 0 0 3 3 3 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase GCV_H PF01597.14 EGC33300.1 - 1.2e-25 89.5 1.8 1.4e-25 89.3 1.3 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EGC33300.1 - 0.018 14.6 0.1 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 Biotin-requiring enzyme PduV-EutP PF10662.4 EGC33300.1 - 0.043 13.3 0.0 0.065 12.7 0.0 1.2 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation EGF_2 PF07974.8 EGC33302.1 - 2.4e-05 24.3 38.0 0.011 15.9 10.7 2.4 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC33302.1 - 0.0029 17.5 15.7 0.22 11.6 2.4 2.7 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC33302.1 - 0.18 11.7 27.2 0.75 9.7 6.8 2.3 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EGC33302.1 - 0.33 10.9 27.3 2 8.4 8.3 2.5 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.8 EGC33303.1 - 4.4e-05 23.5 36.1 0.014 15.5 9.2 2.5 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC33303.1 - 0.014 15.4 17.6 0.068 13.2 2.2 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 EGC33303.1 - 0.023 14.6 25.7 0.095 12.6 5.0 2.6 2 0 0 2 2 2 0 EGF-like domain Laminin_EGF PF00053.19 EGC33303.1 - 1.2 9.0 25.0 3.8 7.5 6.3 2.5 1 1 1 2 2 2 0 Laminin EGF-like (Domains III and V) ABC2_membrane PF01061.19 EGC33304.1 - 1.4e-74 249.7 56.6 9.8e-39 132.6 16.2 2.6 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC33304.1 - 7e-42 142.9 0.1 1.2e-20 74.1 0.0 3.1 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EGC33304.1 - 3.1e-06 26.4 0.0 0.0003 20.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGC33304.1 - 7.6e-05 22.7 0.0 0.066 13.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGC33304.1 - 0.00019 21.5 0.2 0.12 12.5 0.0 3.8 3 1 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EGC33304.1 - 0.00022 20.7 0.8 0.0058 16.1 0.2 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGC33304.1 - 0.00027 20.8 0.0 0.75 9.7 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EGC33304.1 - 0.0023 17.3 0.0 0.0071 15.7 0.0 1.7 2 0 0 2 2 2 1 AAA domain UPF0079 PF02367.12 EGC33304.1 - 0.0035 16.9 0.2 2.2 7.9 0.1 2.6 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 AAA_18 PF13238.1 EGC33304.1 - 0.005 17.1 1.0 0.27 11.5 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EGC33304.1 - 0.017 15.9 0.1 0.16 12.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGC33304.1 - 0.07 13.0 0.1 0.21 11.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC33304.1 - 0.077 12.8 0.0 0.26 11.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGC33304.1 - 0.18 10.5 0.1 2.7 6.7 0.1 2.2 2 0 0 2 2 2 0 ArgK protein Endotoxin_N PF03945.9 EGC33305.1 - 1.2e-06 28.0 5.5 2.4e-06 27.1 3.8 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain Circo_capsid PF02443.10 EGC33306.1 - 0.066 12.5 0.0 0.11 11.8 0.0 1.3 1 0 0 1 1 1 0 Circovirus capsid protein DUF969 PF06149.7 EGC33307.1 - 0.025 13.8 0.0 0.027 13.7 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF969) MAP65_ASE1 PF03999.7 EGC33308.1 - 7.8 4.9 19.9 10 4.6 13.8 1.1 1 0 0 1 1 1 0 Microtubule associated protein (MAP65/ASE1 family) Zip PF02535.17 EGC33308.1 - 9.4 5.1 7.8 12 4.7 5.4 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter LysM PF01476.15 EGC33310.1 - 1.1e-14 53.9 5.3 0.00013 21.7 0.1 3.5 3 0 0 3 3 3 3 LysM domain DPBB_1 PF03330.13 EGC33310.1 - 1.7e-09 37.5 0.1 4.5e-09 36.2 0.0 1.8 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel WGR PF05406.10 EGC33310.1 - 0.16 11.9 1.2 25 4.8 0.0 2.8 3 0 0 3 3 3 0 WGR domain DUF3024 PF11225.3 EGC33310.1 - 0.53 10.2 7.1 20 5.1 0.1 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3024) TSP9 PF11493.3 EGC33310.1 - 6.8 7.3 6.4 72 4.0 0.1 3.7 3 2 0 3 3 3 0 Thylakoid soluble phosphoprotein TSP9 GCV_H PF01597.14 EGC33311.1 - 1.5e-23 82.8 0.2 1.8e-23 82.4 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EGC33311.1 - 0.047 13.3 0.1 0.2 11.3 0.0 1.9 1 1 1 2 2 2 0 Biotin-requiring enzyme GCV_H PF01597.14 EGC33312.1 - 1.6e-34 118.1 0.1 1.9e-34 117.9 0.0 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein GCV_H PF01597.14 EGC33313.1 - 2.3e-39 133.8 0.6 2.7e-39 133.5 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl PF00364.17 EGC33313.1 - 0.00049 19.6 0.1 0.00075 19.0 0.1 1.2 1 0 0 1 1 1 1 Biotin-requiring enzyme Phasin PF05597.6 EGC33313.1 - 0.063 13.0 0.2 0.09 12.5 0.1 1.2 1 0 0 1 1 1 0 Poly(hydroxyalcanoate) granule associated protein (phasin) F-box PF00646.28 EGC33313.1 - 0.27 10.9 1.5 0.38 10.4 1.1 1.2 1 0 0 1 1 1 0 F-box domain PPR_2 PF13041.1 EGC33314.1 - 1.5e-52 175.3 7.8 1.6e-10 40.7 0.0 9.5 4 3 5 9 9 9 7 PPR repeat family PPR_3 PF13812.1 EGC33314.1 - 1.3e-38 128.0 0.0 0.00023 21.2 0.0 10.6 12 0 0 12 12 12 8 Pentatricopeptide repeat domain PPR PF01535.15 EGC33314.1 - 3.5e-38 126.9 22.7 2.1e-05 24.2 0.4 12.2 12 1 0 12 12 12 7 PPR repeat PPR_1 PF12854.2 EGC33314.1 - 4.7e-38 128.3 7.3 2.4e-07 30.1 0.0 10.9 12 0 0 12 12 12 7 PPR repeat ATP13 PF12921.2 EGC33314.1 - 3.4e-06 26.4 4.3 0.95 8.8 0.0 5.9 2 2 3 5 5 5 3 Mitochondrial ATPase expression adh_short_C2 PF13561.1 EGC33314.1 - 0.0044 16.8 0.1 0.0084 15.8 0.1 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF2340 PF10209.4 EGC33314.1 - 0.082 13.0 4.1 0.17 12.0 0.1 2.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2340) Cpn10 PF00166.16 EGC33315.1 - 2.9e-21 75.2 0.0 3.2e-21 75.0 0.0 1.0 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit DUF905 PF06006.7 EGC33316.1 - 9.7e-14 50.4 0.4 2.5 7.5 0.0 9.2 9 0 0 9 9 9 5 Bacterial protein of unknown function (DUF905) CoA_trans PF01144.18 EGC33316.1 - 0.04 13.0 0.0 0.076 12.1 0.0 1.4 1 0 0 1 1 1 0 Coenzyme A transferase Glyco_hydro_25 PF01183.15 EGC33318.1 - 7.4e-10 38.9 0.0 8.8e-10 38.6 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 SNF2_N PF00176.18 EGC33319.1 - 8.1e-53 179.1 2.0 1.5e-48 165.1 0.8 2.4 2 0 0 2 2 2 2 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC33319.1 - 4.6e-08 32.8 1.8 1.3e-07 31.4 0.0 2.7 4 0 0 4 4 4 1 Helicase conserved C-terminal domain Rap_GAP PF02145.10 EGC33320.1 - 1.5e-58 197.2 0.0 3.7e-58 196.0 0.0 1.7 1 0 0 1 1 1 1 Rap/ran-GAP PH PF00169.24 EGC33320.1 - 3.5e-27 94.6 9.3 2e-15 56.8 0.4 3.9 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 EGC33320.1 - 1.2e-13 51.2 15.5 0.00022 21.4 1.7 4.6 2 1 1 3 3 3 3 Pleckstrin homology domain PH_3 PF14593.1 EGC33320.1 - 3.2e-07 30.1 10.3 0.0078 16.0 0.4 4.1 3 1 1 4 4 4 2 PH domain PH_6 PF15406.1 EGC33320.1 - 2.1e-06 27.7 0.1 9.5e-06 25.6 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGC33320.1 - 0.087 12.9 8.8 4.3 7.5 0.1 3.8 1 1 1 2 2 2 0 Pleckstrin homology domain EGF_2 PF07974.8 EGC33326.1 - 2.2e-14 53.3 91.7 0.00016 21.7 11.2 5.7 5 0 0 5 5 5 4 EGF-like domain Laminin_EGF PF00053.19 EGC33326.1 - 0.021 14.7 77.2 0.14 12.1 7.3 6.0 4 2 2 6 6 6 0 Laminin EGF-like (Domains III and V) LRR_8 PF13855.1 EGC33326.1 - 0.077 12.7 8.6 1.2 8.9 0.1 5.3 6 0 0 6 6 6 0 Leucine rich repeat Pkinase_Tyr PF07714.12 EGC33327.1 - 8.3e-62 208.5 0.0 9.7e-62 208.3 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC33327.1 - 8.5e-58 195.5 0.0 1.2e-57 194.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC33327.1 - 0.011 14.6 0.0 0.02 13.8 0.0 1.4 1 1 0 1 1 1 0 Kinase-like APH PF01636.18 EGC33327.1 - 0.2 11.3 0.0 0.68 9.6 0.0 1.7 1 1 1 2 2 2 0 Phosphotransferase enzyme family ABC_membrane_2 PF06472.10 EGC33328.1 - 5.3e-45 153.7 10.7 3e-42 144.6 1.9 2.9 3 0 0 3 3 3 2 ABC transporter transmembrane region 2 ABC_tran PF00005.22 EGC33328.1 - 4.1e-18 66.0 0.1 3.7e-17 62.8 0.0 2.3 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGC33328.1 - 4.9e-05 22.7 0.1 0.00013 21.4 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC33328.1 - 0.00051 20.0 0.0 0.0013 18.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGC33328.1 - 0.0054 15.9 0.0 0.012 14.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC33328.1 - 0.0062 16.6 0.9 0.24 11.5 0.2 3.1 1 1 1 2 2 2 1 AAA domain T2SE PF00437.15 EGC33328.1 - 0.0072 15.2 0.0 0.013 14.4 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein Mg_chelatase PF01078.16 EGC33328.1 - 0.0099 15.0 0.0 0.017 14.2 0.0 1.3 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGC33328.1 - 0.021 14.2 0.1 0.17 11.2 0.0 2.2 1 1 1 2 2 2 0 IstB-like ATP binding protein DUF815 PF05673.8 EGC33328.1 - 0.022 13.6 0.0 0.038 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EGC33328.1 - 0.06 13.6 0.1 4.2 7.7 0.0 3.1 3 0 0 3 3 3 0 AAA domain AAA_10 PF12846.2 EGC33328.1 - 0.072 12.5 0.9 0.13 11.6 0.2 1.7 2 0 0 2 2 2 0 AAA-like domain AAA_17 PF13207.1 EGC33328.1 - 0.079 13.7 1.0 0.67 10.7 0.1 2.8 2 1 0 2 2 2 0 AAA domain SMC_N PF02463.14 EGC33328.1 - 0.11 11.7 5.9 0.025 13.8 0.3 2.4 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain FtsK_SpoIIIE PF01580.13 EGC33328.1 - 0.12 11.8 0.0 0.21 11.0 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_25 PF13481.1 EGC33328.1 - 0.19 11.0 0.0 6.2 6.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain DUF221 PF02714.10 EGC33329.1 - 2.7e-92 309.0 23.6 2.7e-92 309.0 16.4 2.7 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGC33329.1 - 5.4e-39 133.2 1.6 5.4e-39 133.2 1.1 3.4 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGC33329.1 - 2.3e-13 50.4 0.1 3.9e-13 49.7 0.1 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) IncA PF04156.9 EGC33329.1 - 0.014 14.9 0.4 0.26 10.8 0.0 2.9 2 0 0 2 2 2 0 IncA protein Shisa PF13908.1 EGC33329.1 - 0.033 14.3 0.6 0.26 11.4 0.1 2.5 3 0 0 3 3 3 0 Wnt and FGF inhibitory regulator EphA2_TM PF14575.1 EGC33329.1 - 0.042 14.2 0.6 12 6.3 0.0 4.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF221 PF02714.10 EGC33330.1 - 1.9e-93 312.8 26.2 1.9e-93 312.8 18.2 2.0 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGC33330.1 - 2.8e-32 111.4 2.7 2.8e-32 111.4 1.9 3.1 3 0 0 3 3 3 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGC33330.1 - 4e-09 36.8 2.6 5.2e-09 36.5 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF4463) Vpu PF00558.14 EGC33330.1 - 0.00085 18.8 9.0 0.081 12.4 0.1 3.6 3 0 0 3 3 3 2 Vpu protein FNIP PF05725.7 EGC33331.1 - 0.00028 20.7 5.6 0.0067 16.3 0.2 9.0 8 2 0 8 8 8 4 FNIP Repeat SR-25 PF10500.4 EGC33331.1 - 0.13 11.7 17.0 0.2 11.0 11.8 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Period_C PF12114.3 EGC33331.1 - 0.54 9.8 11.8 0.9 9.1 8.2 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region Ssl1 PF04056.9 EGC33332.1 - 2.6e-72 242.4 0.3 3.4e-72 242.1 0.2 1.2 1 0 0 1 1 1 1 Ssl1-like C1_4 PF07975.7 EGC33332.1 - 1.8e-15 56.6 11.5 1.8e-15 56.6 7.9 2.6 2 0 0 2 2 2 1 TFIIH C1-like domain VWA_2 PF13519.1 EGC33332.1 - 5.2e-10 39.6 0.0 1.8e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain FHIPEP PF00771.15 EGC33332.1 - 0.071 11.4 0.3 0.11 10.8 0.2 1.2 1 0 0 1 1 1 0 FHIPEP family DUF3981 PF13139.1 EGC33333.1 - 0.0047 16.9 0.3 0.0047 16.9 0.2 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF3981) FNIP PF05725.7 EGC33335.1 - 2.2e-70 232.3 55.6 3.1e-15 55.8 0.2 8.3 3 3 7 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 EGC33335.1 - 0.00022 21.0 6.2 11 6.0 0.0 6.4 5 2 3 8 8 8 2 Protein of unknown function (DUF1769) DUF3980 PF13140.1 EGC33335.1 - 0.048 13.9 0.0 0.15 12.3 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3980) Iso_dh PF00180.15 EGC33336.1 - 1.9e-79 267.1 0.0 2.3e-79 266.8 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase EGF_2 PF07974.8 EGC33337.1 - 1.2e-40 137.2 268.7 9.4e-05 22.4 9.5 14.5 14 0 0 14 14 14 12 EGF-like domain Laminin_EGF PF00053.19 EGC33337.1 - 0.0059 16.5 221.1 0.11 12.4 5.9 14.7 11 3 3 14 14 14 12 Laminin EGF-like (Domains III and V) SfsA PF03749.8 EGC33337.1 - 0.021 14.2 1.7 2.4 7.5 0.1 2.5 2 0 0 2 2 2 0 Sugar fermentation stimulation protein DUF3430 PF11912.3 EGC33338.1 - 1.9e-25 89.9 12.3 1.9e-25 89.9 8.5 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) FAM219A PF15260.1 EGC33338.1 - 0.0075 16.6 0.1 0.41 10.9 0.0 2.2 2 0 0 2 2 2 1 Protein family FAM219A MIF4G PF02854.14 EGC33339.1 - 1.7e-21 76.6 17.8 1.7e-21 76.6 12.4 3.8 2 2 1 3 3 3 1 MIF4G domain Prefoldin_2 PF01920.15 EGC33339.1 - 0.00081 19.1 2.7 0.00081 19.1 1.9 5.0 3 1 0 4 4 4 1 Prefoldin subunit Tropomyosin_1 PF12718.2 EGC33339.1 - 0.013 15.3 3.5 0.013 15.3 2.4 4.0 5 0 0 5 5 5 0 Tropomyosin like TMF_DNA_bd PF12329.3 EGC33339.1 - 0.015 15.1 5.3 0.015 15.1 3.7 4.2 4 0 0 4 4 4 0 TATA element modulatory factor 1 DNA binding Mto2_bdg PF12808.2 EGC33339.1 - 3.6 7.7 12.5 0.83 9.8 1.5 3.4 3 0 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region IFP_35_N PF07334.8 EGC33339.1 - 3.7 7.5 13.2 0.17 11.8 2.4 3.2 2 1 1 3 3 3 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus DUF3251 PF11622.3 EGC33339.1 - 4.2 6.7 7.9 9.2 5.6 1.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3251) UQ_con PF00179.21 EGC33340.1 - 2.4e-52 176.0 0.0 2.8e-52 175.8 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC33340.1 - 2.5e-05 24.0 0.0 3.1e-05 23.7 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC33340.1 - 0.01 15.7 0.2 0.016 15.0 0.1 1.6 1 1 0 1 1 1 0 RWD domain FA_hydroxylase PF04116.8 EGC33341.1 - 2.5e-17 63.3 16.4 2.5e-17 63.3 11.4 2.4 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily Alg14 PF08660.6 EGC33342.1 - 1.4e-55 187.9 0.0 2.2e-55 187.2 0.0 1.3 1 0 0 1 1 1 1 Oligosaccharide biosynthesis protein Alg14 like Glyco_tran_28_C PF04101.11 EGC33342.1 - 6.5e-24 84.4 0.0 1.2e-23 83.5 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 C-terminal domain Glyco_trans_1_3 PF13528.1 EGC33342.1 - 7.8e-05 22.0 0.0 0.00015 21.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 1 Colipase-like PF15083.1 EGC33343.1 - 1.5e-05 24.8 1.2 1.8e-05 24.5 0.8 1.1 1 0 0 1 1 1 1 Colipase-like Nodulin_late PF07127.6 EGC33343.1 - 0.048 13.7 1.2 0.048 13.7 0.8 2.3 2 1 0 2 2 2 0 Late nodulin protein Prokineticin PF06607.6 EGC33343.1 - 0.088 12.9 0.9 0.11 12.6 0.6 1.2 1 0 0 1 1 1 0 Prokineticin CBM_14 PF01607.19 EGC33343.1 - 0.2 11.6 0.4 0.2 11.6 0.2 1.7 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Nodulin_late PF07127.6 EGC33344.1 - 0.063 13.4 8.5 0.05 13.7 1.4 2.3 1 1 1 2 2 2 0 Late nodulin protein Myticin-prepro PF10690.4 EGC33344.1 - 0.077 13.0 0.9 0.093 12.7 0.7 1.3 1 0 0 1 1 1 0 Myticin pre-proprotein from the mussel UPAR_LY6 PF00021.16 EGC33344.1 - 0.52 10.7 6.2 0.76 10.2 3.7 1.6 1 1 1 2 2 2 0 u-PAR/Ly-6 domain EB PF01683.13 EGC33344.1 - 5.8 7.0 8.9 11 6.2 1.0 2.2 1 1 1 2 2 2 0 EB module Laminin_EGF PF00053.19 EGC33345.1 - 3.1e-09 36.5 47.4 0.0084 16.0 5.2 4.8 2 1 2 4 4 4 4 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC33345.1 - 1.8e-08 34.4 75.4 0.011 15.8 6.2 5.2 5 0 0 5 5 5 4 EGF-like domain TIG PF01833.19 EGC33345.1 - 4.3e-05 23.4 7.4 0.00069 19.5 0.5 4.3 5 0 0 5 5 5 2 IPT/TIG domain Laminin_EGF PF00053.19 EGC33346.1 - 2e-07 30.8 47.1 0.0084 16.0 5.2 4.8 3 1 1 4 4 4 4 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC33346.1 - 4.3e-07 29.9 74.7 0.043 13.9 8.6 5.1 5 0 0 5 5 5 4 EGF-like domain TIG PF01833.19 EGC33346.1 - 6.4e-07 29.2 15.1 0.0003 20.7 0.2 4.5 4 0 0 4 4 4 2 IPT/TIG domain DUF4519 PF15012.1 EGC33346.1 - 1.6 8.6 2.8 3.2 7.7 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) AAA_5 PF07728.9 EGC33347.1 - 5.4e-118 389.0 0.2 3.6e-22 78.5 0.0 10.2 9 0 0 9 9 9 9 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC33347.1 - 1.9e-29 101.8 0.0 1.1e-10 41.2 0.0 6.5 6 0 0 6 6 6 3 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EGC33347.1 - 2.3e-23 82.8 2.5 0.00026 21.1 0.0 8.0 7 0 0 7 7 6 4 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC33347.1 - 1.5e-19 70.7 1.6 0.00063 19.7 0.0 7.3 7 0 0 7 7 7 5 AAA ATPase domain AAA_22 PF13401.1 EGC33347.1 - 3.9e-15 56.1 5.0 0.012 15.7 0.0 8.3 8 0 0 8 8 7 4 AAA domain Sigma54_activat PF00158.21 EGC33347.1 - 6.1e-15 55.0 0.0 0.035 13.5 0.0 5.9 5 0 0 5 5 5 4 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGC33347.1 - 1.4e-13 50.4 0.3 0.0013 17.8 0.0 5.7 6 0 0 6 6 5 4 Zeta toxin T2SE PF00437.15 EGC33347.1 - 4.2e-13 48.8 6.5 0.013 14.4 0.1 6.3 6 0 0 6 6 6 4 Type II/IV secretion system protein AAA_33 PF13671.1 EGC33347.1 - 2.7e-12 46.7 0.0 0.079 12.8 0.0 6.6 7 0 0 7 7 7 3 AAA domain Sigma54_activ_2 PF14532.1 EGC33347.1 - 2.5e-11 43.8 2.3 0.06 13.3 0.0 6.4 7 0 0 7 7 5 3 Sigma-54 interaction domain AAA_17 PF13207.1 EGC33347.1 - 1.5e-09 38.6 32.7 0.0046 17.7 0.0 8.8 9 0 0 9 9 4 4 AAA domain UPF0079 PF02367.12 EGC33347.1 - 8.3e-08 31.9 3.0 5.3 6.7 0.0 6.3 6 0 0 6 6 6 2 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EGC33347.1 - 6.1e-07 29.1 2.0 1.5 8.6 0.2 5.0 5 0 0 5 5 5 2 Part of AAA domain AAA_28 PF13521.1 EGC33347.1 - 1.3e-06 28.4 3.8 1.8 8.4 0.1 5.8 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EGC33347.1 - 4.7e-06 26.0 2.0 7.7 6.1 0.1 5.6 6 0 0 6 6 6 0 P-loop containing region of AAA domain NACHT PF05729.7 EGC33347.1 - 7.2e-06 25.7 4.0 2.6 7.6 0.0 5.4 6 0 0 6 6 6 3 NACHT domain RuvB_N PF05496.7 EGC33347.1 - 0.00014 21.0 0.5 1.7 7.6 0.0 5.4 5 0 0 5 5 5 1 Holliday junction DNA helicase ruvB N-terminus ATP-synt_ab PF00006.20 EGC33347.1 - 0.0012 18.3 0.1 2 7.8 0.0 4.0 4 0 0 4 4 4 1 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EGC33347.1 - 0.0044 16.6 0.8 3.3 7.2 0.0 4.9 4 1 0 4 4 4 1 Chloramphenicol phosphotransferase-like protein AAA_18 PF13238.1 EGC33347.1 - 0.0044 17.3 0.5 0.045 14.0 0.1 11.6 12 2 0 12 12 7 4 AAA domain AAA_25 PF13481.1 EGC33347.1 - 0.0048 16.3 0.3 4.4 6.6 0.0 4.5 5 0 0 5 5 5 1 AAA domain Got1 PF04178.7 EGC33349.1 - 5e-26 91.1 23.4 6.8e-26 90.6 16.3 1.2 1 0 0 1 1 1 1 Got1/Sft2-like family DUF3290 PF11694.3 EGC33349.1 - 0.5 10.0 6.3 0.091 12.4 1.4 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3290) TMCO5 PF14992.1 EGC33349.1 - 2.3 7.2 5.5 9.2 5.2 0.1 2.1 2 0 0 2 2 2 0 TMCO5 family Ribosomal_L7Ae PF01248.21 EGC33350.1 - 1.6e-12 46.7 0.2 4.9e-12 45.1 0.1 1.8 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Nrap PF03813.9 EGC33351.1 - 4.7e-149 497.7 35.8 1e-146 490.0 24.8 2.2 1 1 0 1 1 1 1 Nrap protein adh_short PF00106.20 EGC33352.1 - 3.4e-30 105.1 0.5 5.4e-30 104.4 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase SCP2 PF02036.12 EGC33352.1 - 3.3e-25 88.3 0.2 6.2e-25 87.4 0.2 1.5 1 0 0 1 1 1 1 SCP-2 sterol transfer family KR PF08659.5 EGC33352.1 - 2.9e-16 59.6 0.2 5e-16 58.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Alkyl_sulf_C PF14864.1 EGC33352.1 - 1.6e-05 24.8 0.1 2.6e-05 24.1 0.1 1.3 1 0 0 1 1 1 1 Alkyl sulfatase C-terminal Epimerase PF01370.16 EGC33352.1 - 0.013 14.9 0.1 0.076 12.4 0.1 2.0 1 1 0 2 2 2 0 NAD dependent epimerase/dehydratase family DAO PF01266.19 EGC33352.1 - 0.022 13.6 0.3 0.033 13.1 0.2 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Myb_DNA-binding PF00249.26 EGC33353.1 - 8.4e-31 105.7 1.5 1.7e-12 47.1 0.1 3.2 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC33353.1 - 3.1e-24 84.8 11.3 6.8e-08 32.5 0.4 4.1 4 0 0 4 4 4 3 Myb-like DNA-binding domain Death PF00531.17 EGC33353.1 - 0.099 12.4 0.5 1.2 8.9 0.1 2.2 2 0 0 2 2 2 0 Death domain PGC7_Stella PF15549.1 EGC33353.1 - 6.2 6.7 7.5 7.4 6.5 4.0 2.0 1 1 0 1 1 1 0 PGC7/Stella/Dppa3 domain MADF_DNA_bdg PF10545.4 EGC33353.1 - 7.9 6.7 10.1 7.4 6.8 0.3 3.4 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like SPX PF03105.14 EGC33354.1 - 0.006 16.3 5.5 0.0071 16.1 3.8 1.1 1 0 0 1 1 1 1 SPX domain AAA_23 PF13476.1 EGC33354.1 - 0.088 13.1 10.7 0.1 12.8 7.4 1.1 1 0 0 1 1 1 0 AAA domain Gly-rich_Ago1 PF12764.2 EGC33354.1 - 3.7 8.2 9.8 7.5 7.2 6.8 1.5 1 1 0 1 1 1 0 Glycine-rich region of argonaut VCBS PF13517.1 EGC33355.1 - 3.3e-17 62.5 25.1 1.9e-08 34.5 3.0 5.6 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGC33355.1 - 6.9e-16 57.4 15.9 7.8e-05 22.2 0.3 6.4 6 0 0 6 6 6 5 FG-GAP repeat PQQ_2 PF13360.1 EGC33355.1 - 5.4e-07 29.3 0.0 0.09 12.2 0.0 3.4 3 0 0 3 3 3 2 PQQ-like domain BBS2_Mid PF14783.1 EGC33355.1 - 0.00076 19.2 1.6 22 4.8 0.0 5.5 5 0 0 5 5 5 0 Ciliary BBSome complex subunit 2, middle region PQQ_3 PF13570.1 EGC33355.1 - 0.0089 16.2 8.5 3.5 8.0 0.1 5.6 6 0 0 6 6 6 1 PQQ-like domain PQQ PF01011.16 EGC33355.1 - 0.01 15.3 4.4 0.15 11.6 0.0 4.2 5 0 0 5 5 5 0 PQQ enzyme repeat TcdB_toxin_midN PF12256.3 EGC33355.1 - 0.021 14.2 10.0 0.89 8.9 0.0 5.5 4 1 2 6 6 6 0 Insecticide toxin TcdB middle/N-terminal region RabGAP-TBC PF00566.13 EGC33356.1 - 2.2e-08 33.8 15.5 2.2e-08 33.8 10.7 3.3 3 1 0 3 3 3 1 Rab-GTPase-TBC domain STAT_int PF02865.12 EGC33356.1 - 0.019 14.9 0.5 0.062 13.2 0.4 1.8 1 0 0 1 1 1 0 STAT protein, protein interaction domain Sec61_beta PF03911.11 EGC33357.1 - 5e-15 55.0 0.8 5.9e-15 54.7 0.6 1.1 1 0 0 1 1 1 1 Sec61beta family PARP PF00644.15 EGC33358.1 - 2e-66 223.3 1.5 7.8e-65 218.1 0.0 2.7 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC33358.1 - 5.1e-45 152.4 4.5 1.6e-44 150.7 2.8 2.1 2 0 0 2 2 2 1 Poly(ADP-ribose) polymerase, regulatory domain PADR1 PF08063.7 EGC33358.1 - 9.7e-20 69.7 0.6 2.3e-19 68.5 0.4 1.7 1 0 0 1 1 1 1 PADR1 (NUC008) domain zf-PARP PF00645.13 EGC33358.1 - 5.6e-17 61.7 1.2 2.7e-16 59.5 0.9 2.3 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region WGR PF05406.10 EGC33358.1 - 1.9e-15 56.5 0.2 4.5e-15 55.3 0.2 1.7 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EGC33358.1 - 2.9e-05 24.1 0.1 0.00013 22.0 0.1 2.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DiS_P_DiS PF06750.8 EGC33358.1 - 0.1 12.4 0.4 1.2 8.9 0.0 2.7 3 0 0 3 3 3 0 Bacterial Peptidase A24 N-terminal domain NDUFA12 PF05071.11 EGC33359.1 - 1.4e-24 86.5 0.2 1.6e-24 86.3 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase subunit NDUFA12 PIP5K PF01504.13 EGC33360.1 - 1.7e-79 266.4 6.7 1.6e-78 263.3 4.7 2.5 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase FAD_binding_3 PF01494.14 EGC33361.1 - 1.7e-22 79.9 0.0 1.1e-10 41.1 0.0 2.5 2 1 0 2 2 2 2 FAD binding domain SE PF08491.5 EGC33361.1 - 3.9e-07 29.1 0.1 1e-06 27.7 0.1 1.7 2 0 0 2 2 2 1 Squalene epoxidase Trp_halogenase PF04820.9 EGC33361.1 - 6e-06 25.1 0.0 0.00015 20.5 0.0 2.4 2 0 0 2 2 2 1 Tryptophan halogenase Lycopene_cycl PF05834.7 EGC33361.1 - 1.7e-05 23.9 0.0 0.0029 16.6 0.0 2.2 2 0 0 2 2 2 2 Lycopene cyclase protein DAO PF01266.19 EGC33361.1 - 0.0003 19.8 0.0 0.0005 19.0 0.0 1.3 1 0 0 1 1 1 1 FAD dependent oxidoreductase NAD_Gly3P_dh_N PF01210.18 EGC33361.1 - 0.01 15.5 0.2 0.02 14.6 0.1 1.5 1 1 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus Pyr_redox PF00070.22 EGC33361.1 - 0.017 15.4 0.0 0.046 14.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC33361.1 - 0.019 14.9 0.0 0.042 13.8 0.0 1.6 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain Pyr_redox_2 PF07992.9 EGC33361.1 - 0.024 14.5 0.0 0.077 12.8 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGC33361.1 - 0.033 13.3 0.1 0.085 11.9 0.0 1.7 2 0 0 2 2 2 0 Thi4 family NAD_binding_9 PF13454.1 EGC33361.1 - 0.07 12.9 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pkinase PF00069.20 EGC33362.1 - 9.7e-57 192.0 0.1 1.6e-56 191.3 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33362.1 - 1.8e-29 102.6 0.0 2.5e-29 102.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGC33362.1 - 4.2e-05 22.9 0.1 7.6e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC33362.1 - 0.0077 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PMR5N PF14416.1 EGC33362.1 - 0.013 15.5 1.9 0.013 15.5 1.3 1.8 2 0 0 2 2 2 0 PMR5 N terminal Domain Kinase-like PF14531.1 EGC33362.1 - 0.023 13.6 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like Pkinase PF00069.20 EGC33363.1 - 4e-52 176.9 0.2 8.2e-52 175.9 0.1 1.5 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33363.1 - 4.6e-29 101.2 0.0 6.5e-29 100.7 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33363.1 - 0.00042 19.3 0.0 0.00055 18.9 0.0 1.1 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGC33363.1 - 0.00079 18.8 0.1 0.0018 17.6 0.0 1.7 1 1 1 2 2 2 1 RIO1 family APH PF01636.18 EGC33363.1 - 0.0014 18.3 0.0 0.002 17.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC33363.1 - 0.0058 15.7 0.1 0.0087 15.1 0.1 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family ACDC PF14733.1 EGC33363.1 - 0.015 15.4 0.5 0.038 14.1 0.1 1.8 1 1 0 1 1 1 0 AP2-coincident C-terminal Pkinase PF00069.20 EGC33364.1 - 2.4e-61 207.1 0.1 3.7e-61 206.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33364.1 - 1.7e-31 109.2 0.0 2.2e-31 108.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33364.1 - 1.6e-08 33.9 0.0 2.2e-08 33.3 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC33364.1 - 0.00011 22.0 0.0 0.00019 21.2 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC33364.1 - 0.00024 20.5 0.0 0.00041 19.7 0.0 1.3 1 0 0 1 1 1 1 RIO1 family Kdo PF06293.9 EGC33364.1 - 0.0021 17.1 0.0 0.0034 16.4 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family SapB_1 PF05184.10 EGC33365.1 - 7e-20 70.3 15.9 1.1e-10 41.0 3.6 3.1 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC33365.1 - 7.4e-14 51.4 5.9 3.7e-09 36.4 0.4 3.0 3 0 0 3 3 3 2 Saposin-like type B, region 2 Herpes_UL92 PF03048.9 EGC33365.1 - 0.00043 19.9 4.5 0.19 11.3 0.1 2.2 1 1 1 2 2 2 2 UL92 family Herpes_env PF01673.13 EGC33365.1 - 0.039 12.5 1.5 0.16 10.4 0.5 1.9 2 0 0 2 2 2 0 Herpesvirus putative major envelope glycoprotein WD40 PF00400.27 EGC33367.1 - 1.1e-20 72.6 10.9 1e-06 28.3 0.1 5.4 4 1 1 5 5 5 4 WD domain, G-beta repeat SnoaL_2 PF12680.2 EGC33367.1 - 0.0036 17.6 0.0 0.0093 16.3 0.0 1.8 1 0 0 1 1 1 1 SnoaL-like domain RNase_Zc3h12a_2 PF14626.1 EGC33367.1 - 0.076 12.8 0.1 0.36 10.6 0.0 2.2 2 1 0 2 2 2 0 Zc3h12a-like Ribonuclease NYN domain DPPIV_N PF00930.16 EGC33367.1 - 0.11 11.0 5.1 1.1 7.7 0.9 2.6 2 1 0 2 2 2 0 Dipeptidyl peptidase IV (DPP IV) N-terminal region DUF676 PF05057.9 EGC33368.1 - 7e-38 130.1 1.2 1.2e-37 129.2 0.4 1.7 1 1 0 1 1 1 1 Putative serine esterase (DUF676) DUF3657 PF12394.3 EGC33368.1 - 6.1e-19 67.8 0.2 6.1e-19 67.8 0.1 3.8 3 0 0 3 3 3 1 Protein of unknown function (DUF3657) PGAP1 PF07819.8 EGC33368.1 - 1.7e-07 31.0 0.9 1.7e-07 31.0 0.6 2.2 2 1 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGC33368.1 - 0.00015 21.5 0.0 0.00026 20.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGC33368.1 - 0.00058 19.4 0.1 0.0014 18.2 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_6 PF12697.2 EGC33368.1 - 0.015 15.1 0.0 0.035 13.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF829 PF05705.9 EGC33369.1 - 7.4e-43 146.9 0.7 1.3e-42 146.1 0.5 1.4 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Branch PF02485.16 EGC33369.1 - 0.028 13.5 0.6 0.041 13.0 0.4 1.2 1 0 0 1 1 1 0 Core-2/I-Branching enzyme Glyco_hydro_35 PF01301.14 EGC33370.1 - 7.3e-96 321.2 1.9 7.3e-96 321.2 1.3 1.7 2 0 0 2 2 2 1 Glycosyl hydrolases family 35 Orthoreo_P17 PF07272.6 EGC33371.1 - 0.077 12.7 0.5 0.14 11.9 0.1 1.6 2 0 0 2 2 2 0 Orthoreovirus P17 protein DUF1980 PF09323.5 EGC33371.1 - 7.8 6.1 7.1 3 7.5 3.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) IncA PF04156.9 EGC33372.1 - 0.0077 15.8 2.7 0.43 10.1 0.0 2.3 2 0 0 2 2 2 2 IncA protein DUF1713 PF08213.6 EGC33373.1 - 1.3e-12 47.0 18.6 1.8e-12 46.6 12.9 1.2 1 0 0 1 1 1 1 Mitochondrial domain of unknown function (DUF1713) Myb_Cef PF11831.3 EGC33373.1 - 0.0082 15.3 1.0 0.0096 15.1 0.7 1.3 1 0 0 1 1 1 1 pre-mRNA splicing factor component DUF3439 PF11921.3 EGC33373.1 - 0.39 10.4 5.5 0.66 9.7 3.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) CBM49 PF09478.5 EGC33374.1 - 2.4e-17 62.7 4.5 4.6e-17 61.8 3.1 1.4 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 dCMP_cyt_deam_1 PF00383.17 EGC33374.1 - 1.1e-11 44.2 0.3 2e-11 43.4 0.2 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC33374.1 - 0.01 15.6 0.3 1.3 8.8 0.2 2.3 1 1 0 1 1 1 0 Bd3614-like deaminase Nuf2 PF03800.9 EGC33375.1 - 1.6e-28 99.5 0.0 1.6e-28 99.5 0.0 3.7 3 1 0 3 3 3 1 Nuf2 family YbaJ PF10757.4 EGC33375.1 - 0.017 15.2 1.9 0.017 15.2 1.3 2.4 2 0 0 2 2 2 0 Biofilm formation regulator YbaJ Pkinase PF00069.20 EGC33376.1 - 5.1e-70 235.5 0.1 5.7e-70 235.4 0.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33376.1 - 4.1e-34 117.8 0.0 5.1e-34 117.5 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33376.1 - 2.5e-09 36.5 0.0 3.2e-09 36.1 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC33376.1 - 2.6e-06 26.6 0.0 4.1e-06 25.9 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC33376.1 - 0.025 14.3 0.0 0.035 13.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family YrbL-PhoP_reg PF10707.4 EGC33376.1 - 0.053 12.8 0.2 0.088 12.1 0.1 1.4 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Mt_ATP-synt_D PF05873.7 EGC33377.1 - 0.00012 21.7 1.3 0.00018 21.2 0.9 1.3 1 0 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) GldM_N PF12081.3 EGC33377.1 - 0.017 14.6 4.0 0.026 14.0 2.8 1.2 1 0 0 1 1 1 0 GldM N-terminal domain TetR_C_5 PF08360.6 EGC33377.1 - 0.044 13.7 3.6 0.089 12.7 2.5 1.5 1 0 0 1 1 1 0 QacR-like protein, C-terminal region PhoPQ_related PF10142.4 EGC33378.1 - 1.7e-115 385.4 2.0 2e-115 385.2 1.4 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DndB PF14072.1 EGC33378.1 - 0.043 12.9 0.4 0.79 8.8 0.1 2.2 2 0 0 2 2 2 0 DNA-sulfur modification-associated Abhydrolase_5 PF12695.2 EGC33378.1 - 0.045 13.5 0.0 0.098 12.4 0.0 1.6 2 0 0 2 2 2 0 Alpha/beta hydrolase family Acetyltransf_1 PF00583.19 EGC33380.1 - 1.1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGC33380.1 - 9.8e-07 28.4 0.0 1.6e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGC33380.1 - 1.7e-05 24.8 0.0 3.1e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC33380.1 - 0.001 18.9 0.2 0.0026 17.5 0.1 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC33380.1 - 0.0013 18.8 0.0 0.002 18.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FNIP PF05725.7 EGC33381.1 - 6.7e-23 80.3 43.9 5.2e-10 39.1 1.2 9.1 7 3 2 9 9 9 5 FNIP Repeat LRR_8 PF13855.1 EGC33381.1 - 8.1 6.2 29.9 0.36 10.5 3.7 5.7 3 2 3 6 6 6 0 Leucine rich repeat WD40 PF00400.27 EGC33382.1 - 5.8e-26 89.3 10.8 1.9e-10 40.2 0.8 3.1 3 0 0 3 3 3 3 WD domain, G-beta repeat IKI3 PF04762.7 EGC33382.1 - 0.0084 13.9 0.8 0.016 13.0 0.5 1.5 1 1 0 1 1 1 1 IKI3 family Nup160 PF11715.3 EGC33382.1 - 0.024 12.7 0.5 0.029 12.5 0.3 1.1 1 0 0 1 1 1 0 Nucleoporin Nup120/160 Rav1p_C PF12234.3 EGC33382.1 - 0.031 12.4 0.2 0.036 12.2 0.1 1.1 1 0 0 1 1 1 0 RAVE protein 1 C terminal UT PF03253.9 EGC33383.1 - 1.1e-52 178.8 22.8 1.3e-52 178.5 15.8 1.0 1 0 0 1 1 1 1 Urea transporter Ndc1_Nup PF09531.5 EGC33384.1 - 3e-06 25.9 0.2 3e-06 25.9 0.2 4.7 2 2 1 3 3 3 1 Nucleoporin protein Ndc1-Nup Beta_helix PF13229.1 EGC33385.1 - 1.6e-15 57.2 41.7 2.8e-09 36.9 10.5 4.3 2 2 1 3 3 3 2 Right handed beta helix region NosD PF05048.8 EGC33385.1 - 9.9e-13 47.7 30.4 4e-09 35.9 6.6 4.4 2 1 2 4 4 4 3 Periplasmic copper-binding protein (NosD) End_N_terminal PF12218.3 EGC33385.1 - 0.0041 16.5 0.0 0.0093 15.4 0.0 1.6 1 0 0 1 1 1 1 N terminal extension of bacteriophage endosialidase Dzip-like_N PF13815.1 EGC33386.1 - 8e-17 61.1 4.5 8e-17 61.1 3.1 8.9 6 3 2 9 9 9 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal zf-RING_2 PF13639.1 EGC33387.1 - 1.1e-09 37.9 11.2 2.2e-09 37.0 7.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC33387.1 - 2.1e-06 27.2 7.8 3.9e-06 26.4 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33387.1 - 2.3e-06 27.6 6.6 4.9e-06 26.5 4.6 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC33387.1 - 3.5e-05 23.3 13.7 8.9e-05 22.0 9.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33387.1 - 5e-05 23.2 13.3 0.00011 22.2 9.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33387.1 - 0.0056 16.3 12.2 0.0056 16.3 8.4 1.8 2 0 0 2 2 2 1 zinc-RING finger domain Baculo_RING PF05883.6 EGC33387.1 - 0.016 15.0 5.8 0.039 13.7 4.0 1.7 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EGC33387.1 - 0.016 15.0 12.0 0.043 13.6 8.3 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC33387.1 - 0.036 13.9 2.9 0.079 12.8 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4094 PF13334.1 EGC33387.1 - 0.57 10.5 0.0 0.57 10.5 0.0 4.7 4 2 1 5 5 5 0 Domain of unknown function (DUF4094) Kinesin PF00225.18 EGC33388.1 - 4.7e-114 380.5 1.0 4.7e-114 380.5 0.7 3.2 3 1 0 3 3 3 1 Kinesin motor domain ApoO PF09769.4 EGC33388.1 - 3.1 7.4 12.0 6.8 6.3 0.1 3.6 3 0 0 3 3 3 0 Apolipoprotein O Cullin PF00888.17 EGC33390.1 - 4.8e-56 190.5 20.7 4.8e-56 190.5 14.3 3.2 1 1 1 2 2 2 1 Cullin family APC2 PF08672.6 EGC33390.1 - 4.2e-19 68.5 1.8 2.4e-18 66.1 1.3 2.5 1 0 0 1 1 1 1 Anaphase promoting complex (APC) subunit 2 SPARC_Ca_bdg PF10591.4 EGC33390.1 - 2.4 8.2 13.2 0.065 13.2 0.9 4.0 3 0 0 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region Lon_C PF05362.8 EGC33391.1 - 2.4e-58 196.8 0.0 5.6e-58 195.6 0.0 1.6 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGC33391.1 - 1.1e-25 90.3 0.0 3.5e-25 88.7 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGC33391.1 - 9.3e-07 28.9 0.0 3.4e-06 27.0 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGC33391.1 - 2.2e-06 27.8 0.5 0.00021 21.4 0.1 3.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC33391.1 - 2.9e-06 28.0 0.1 3.1e-05 24.7 0.0 2.7 3 0 0 3 3 2 1 AAA domain AAA_5 PF07728.9 EGC33391.1 - 3.1e-06 26.9 0.0 6.9e-06 25.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGC33391.1 - 5.6e-06 25.8 0.0 1.1e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 Subunit ChlI of Mg-chelatase RuvB_N PF05496.7 EGC33391.1 - 7.1e-06 25.2 0.1 2.6e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGC33391.1 - 2.1e-05 23.4 7.2 0.00021 20.1 0.0 3.0 3 0 0 3 3 3 2 TIP49 C-terminus AAA_14 PF13173.1 EGC33391.1 - 8.8e-05 22.4 1.3 0.0012 18.7 0.0 3.2 2 1 2 4 4 4 1 AAA domain AAA_16 PF13191.1 EGC33391.1 - 0.00012 22.1 0.0 0.00052 20.0 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGC33391.1 - 0.00048 20.4 0.0 0.00048 20.4 0.0 4.5 3 1 1 4 4 3 1 AAA domain AAA_3 PF07726.6 EGC33391.1 - 0.003 17.1 0.0 0.015 14.9 0.0 2.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_19 PF13245.1 EGC33391.1 - 0.011 15.4 0.2 0.021 14.5 0.1 1.4 1 0 0 1 1 1 0 Part of AAA domain MobB PF03205.9 EGC33391.1 - 0.011 15.3 1.0 0.059 13.0 0.0 2.4 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGC33391.1 - 0.017 14.9 0.0 0.04 13.7 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC33391.1 - 0.037 13.6 0.0 0.081 12.5 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_25 PF13481.1 EGC33391.1 - 0.068 12.5 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGC33391.1 - 0.072 12.2 0.2 0.22 10.6 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGC33391.1 - 0.084 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 EGC33391.1 - 0.097 12.5 0.0 0.097 12.5 0.0 3.1 3 1 1 4 4 4 0 Shikimate kinase ABC_tran PF00005.22 EGC33391.1 - 0.13 12.5 0.1 0.13 12.5 0.1 3.8 4 1 0 4 4 3 0 ABC transporter PhoPQ_related PF10142.4 EGC33392.1 - 9.5e-118 392.8 5.8 1.1e-117 392.6 4.0 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 EGC33392.1 - 0.0074 16.0 0.0 0.012 15.3 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family PRELI PF04707.9 EGC33393.1 - 0.0042 16.6 0.4 0.006 16.1 0.3 1.2 1 0 0 1 1 1 1 PRELI-like family Y1_Tnp PF01797.11 EGC33393.1 - 0.022 14.6 1.2 0.034 14.0 0.1 1.8 1 1 1 2 2 2 0 Transposase IS200 like DUF1043 PF06295.7 EGC33393.1 - 0.09 12.4 0.1 0.2 11.3 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) RNase_T PF00929.19 EGC33394.1 - 2e-08 34.6 0.1 5e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Exonuclease 7TM_GPCR_Srb PF02175.11 EGC33394.1 - 0.0015 18.1 1.0 0.0029 17.1 0.7 1.4 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Srb Ribonucleas_3_3 PF14622.1 EGC33395.1 - 0.046 13.6 0.1 0.049 13.5 0.0 1.1 1 0 0 1 1 1 0 Ribonuclease-III-like DUF912 PF06024.7 EGC33397.1 - 1.3 9.0 4.7 1.4 9.0 3.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 EGC33397.1 - 1.7 9.0 9.7 1.9 8.9 6.7 1.1 1 0 0 1 1 1 0 Secretin N-terminal domain EGF_2 PF07974.8 EGC33399.1 - 0.0062 16.6 8.7 0.015 15.4 6.0 1.6 1 0 0 1 1 1 1 EGF-like domain TIG PF01833.19 EGC33401.1 - 1.5e-16 60.1 48.7 8.1e-07 28.9 3.6 7.7 8 0 0 8 8 8 6 IPT/TIG domain GATA PF00320.22 EGC33403.1 - 1.7e-07 30.4 4.4 3e-07 29.6 3.0 1.3 1 0 0 1 1 1 1 GATA zinc finger Homeobox PF00046.24 EGC33404.1 - 1.1e-13 50.5 2.9 3.1e-07 29.8 0.1 2.8 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 EGC33404.1 - 3.3e-06 26.6 0.1 0.012 15.2 0.0 2.7 2 0 0 2 2 2 2 Homeobox KN domain GATA PF00320.22 EGC33405.1 - 2.9e-06 26.5 10.1 5.1e-06 25.7 7.0 1.4 1 0 0 1 1 1 1 GATA zinc finger RNase_T PF00929.19 EGC33407.1 - 0.0026 18.0 0.1 0.0057 16.9 0.0 1.6 1 0 0 1 1 1 1 Exonuclease PPK2 PF03976.9 EGC33407.1 - 0.027 13.7 0.3 0.42 9.8 0.0 2.5 2 1 1 3 3 3 0 Polyphosphate kinase 2 (PPK2) DUF4200 PF13863.1 EGC33408.1 - 0.49 10.3 43.8 0.69 9.8 30.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) AlaDh_PNT_C PF01262.16 EGC33408.1 - 7.3 6.1 10.7 0.96 8.9 4.0 1.8 1 1 1 2 2 2 0 Alanine dehydrogenase/PNT, C-terminal domain HMG_box PF00505.14 EGC33409.1 - 2.5e-18 66.1 2.6 2.9e-18 65.9 1.8 1.1 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGC33409.1 - 4e-14 52.7 2.8 5e-14 52.4 1.9 1.1 1 0 0 1 1 1 1 HMG-box domain TIG PF01833.19 EGC33410.1 - 3.2e-09 36.6 58.0 3.4e-05 23.7 3.0 7.8 6 1 1 7 7 7 6 IPT/TIG domain CARDB PF07705.6 EGC33410.1 - 0.00055 19.9 1.3 0.00055 19.9 0.9 3.9 5 1 0 5 5 5 1 CARDB FNIP PF05725.7 EGC33411.1 - 6.1e-31 106.1 43.1 1.5e-12 47.2 4.4 4.8 4 1 1 5 5 5 5 FNIP Repeat KR PF08659.5 EGC33412.1 - 1.2e-07 31.5 0.0 1.8e-07 31.0 0.0 1.3 1 0 0 1 1 1 1 KR domain PP-binding PF00550.20 EGC33412.1 - 0.00032 20.9 0.0 0.00065 19.9 0.0 1.5 1 0 0 1 1 1 1 Phosphopantetheine attachment site TTL PF03133.10 EGC33412.1 - 0.03 13.2 0.1 0.043 12.7 0.1 1.2 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family ketoacyl-synt PF00109.21 EGC33413.1 - 1.7e-41 142.4 0.0 2.5e-41 141.8 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC33413.1 - 7.1e-21 74.8 0.0 8.5e-11 41.7 0.0 3.2 3 0 0 3 3 3 3 Acyl transferase domain Methyltransf_12 PF08242.7 EGC33413.1 - 2.3e-20 72.8 0.0 1.2e-19 70.6 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain PS-DH PF14765.1 EGC33413.1 - 4.8e-20 71.8 0.0 6.9e-20 71.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Ketoacyl-synt_C PF02801.17 EGC33413.1 - 2.8e-19 69.1 0.0 1.6e-18 66.6 0.0 2.2 1 1 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain ADH_N PF08240.7 EGC33413.1 - 2.4e-09 36.9 0.0 5.7e-09 35.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_31 PF13847.1 EGC33413.1 - 1.7e-08 34.1 0.3 1.7e-08 34.1 0.2 3.5 4 1 0 4 4 4 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC33413.1 - 4.5e-08 32.9 0.0 1e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC33413.1 - 8.3e-08 32.6 0.0 2.5e-07 31.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC33413.1 - 0.00051 20.5 0.1 0.0042 17.6 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC33413.1 - 0.0072 17.2 0.0 0.016 16.0 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC33413.1 - 0.028 13.4 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain TIG PF01833.19 EGC33414.1 - 8.4e-14 51.3 50.5 9.4e-06 25.5 1.5 7.9 7 1 1 8 8 8 4 IPT/TIG domain CARDB PF07705.6 EGC33414.1 - 0.019 15.0 0.7 0.019 15.0 0.5 3.8 5 0 0 5 5 5 0 CARDB TBP-binding PF09247.6 EGC33414.1 - 0.2 11.9 2.0 0.4 10.9 0.3 2.1 2 0 0 2 2 2 0 TATA box-binding protein binding Ribosomal_S15 PF00312.17 EGC33415.1 - 4.5e-16 58.3 6.1 8.7e-16 57.4 1.8 2.9 2 0 0 2 2 2 1 Ribosomal protein S15 Pcc1 PF09341.5 EGC33416.1 - 9.7e-11 41.5 0.1 1.1e-10 41.4 0.0 1.0 1 0 0 1 1 1 1 Transcription factor Pcc1 FHA PF00498.21 EGC33417.1 - 1.2e-16 60.5 0.0 2.8e-16 59.3 0.0 1.6 1 0 0 1 1 1 1 FHA domain CytochromB561_N PF09786.4 EGC33417.1 - 0.74 8.1 15.9 1.3 7.3 11.0 1.4 1 1 0 1 1 1 0 Cytochrome B561, N terminal DUF572 PF04502.8 EGC33417.1 - 1 8.4 23.6 1.1 8.3 4.9 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Bul1_C PF04426.7 EGC33417.1 - 1.2 8.3 12.3 0.47 9.6 2.1 2.1 2 0 0 2 2 2 0 Bul1 C terminus Drf_GBD PF06371.8 EGC33417.1 - 4.8 6.4 10.1 0.22 10.8 2.5 2.0 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain Nop25 PF09805.4 EGC33417.1 - 9.9 6.2 24.3 1.7 8.7 6.4 2.3 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) DUF3808 PF10300.4 EGC33419.1 - 1.4e-43 149.2 6.5 2.7e-43 148.2 4.5 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF3808) TPR_12 PF13424.1 EGC33419.1 - 3.8e-07 29.9 2.2 0.0019 18.1 0.9 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC33419.1 - 1.2e-06 27.9 9.1 0.18 11.7 0.2 5.9 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC33419.1 - 7.3e-05 22.9 3.9 0.096 13.1 0.1 4.9 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC33419.1 - 8.7e-05 22.0 15.4 0.027 14.2 0.3 5.1 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC33419.1 - 0.00023 21.2 2.5 0.00023 21.2 1.7 4.1 4 1 0 4 4 4 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGC33419.1 - 0.0013 18.3 8.0 0.13 11.9 0.1 3.9 3 2 0 3 3 3 2 TPR repeat PPR PF01535.15 EGC33419.1 - 0.0039 17.0 1.4 0.22 11.5 0.0 3.7 4 0 0 4 4 3 1 PPR repeat ECM1 PF05782.6 EGC33419.1 - 0.032 12.9 0.9 0.057 12.1 0.2 1.6 2 0 0 2 2 2 0 Extracellular matrix protein 1 (ECM1) DUF3245 PF11595.3 EGC33419.1 - 0.083 13.1 1.3 0.39 11.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3245) TPR_1 PF00515.23 EGC33419.1 - 0.17 11.5 17.1 2.3 7.9 0.1 5.5 6 0 0 6 6 6 0 Tetratricopeptide repeat LRR_6 PF13516.1 EGC33420.1 - 2.6e-11 42.3 32.0 0.018 15.0 0.1 10.8 11 1 1 12 12 12 4 Leucine Rich repeat Myosin_TH1 PF06017.8 EGC33420.1 - 0.0036 16.6 2.2 0.0078 15.5 1.5 1.5 1 0 0 1 1 1 1 Myosin tail LRR_1 PF00560.28 EGC33420.1 - 0.013 15.4 6.9 23 5.5 0.0 6.7 6 2 0 6 6 6 0 Leucine Rich Repeat LRR_8 PF13855.1 EGC33420.1 - 0.037 13.7 11.8 12 5.7 0.1 5.2 3 1 2 5 5 5 0 Leucine rich repeat PH_3 PF14593.1 EGC33420.1 - 0.32 10.8 3.8 0.28 11.0 1.4 1.8 2 0 0 2 2 2 0 PH domain DUF221 PF02714.10 EGC33421.1 - 1.2e-10 40.8 27.5 1.2e-10 40.8 19.1 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF221 RNA_pol_Rpb8 PF03870.10 EGC33422.1 - 0.091 12.9 0.0 0.21 11.7 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase Rpb8 PTPA PF03095.10 EGC33423.1 - 2.4e-112 374.9 0.1 3.1e-112 374.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotyrosyl phosphate activator (PTPA) protein KOG2701 PF09762.4 EGC33424.1 - 2.2e-64 216.8 0.0 2.2e-64 216.8 0.0 3.8 3 1 0 3 3 3 1 Coiled-coil domain-containing protein (DUF2037) Tn7_Tnp_TnsA_C PF08721.6 EGC33424.1 - 0.26 11.3 4.2 0.29 11.1 1.0 2.7 2 0 0 2 2 2 0 TnsA endonuclease C terminal RNase_HII PF01351.13 EGC33424.1 - 2.2 7.8 9.3 0.25 10.9 2.7 2.3 2 0 0 2 2 2 0 Ribonuclease HII TRAPPC-Trs85 PF12739.2 EGC33425.1 - 7.2e-66 222.5 2.2 2.2e-64 217.6 0.2 3.0 2 1 0 2 2 2 1 ER-Golgi trafficking TRAPP I complex 85 kDa subunit DUF3656 PF12392.3 EGC33425.1 - 0.013 15.5 0.1 0.66 10.0 0.0 2.6 2 0 0 2 2 2 0 Collagenase Transglut_C PF00927.17 EGC33425.1 - 0.018 15.0 0.1 2.1 8.4 0.0 3.8 4 0 0 4 4 4 0 Transglutaminase family, C-terminal ig like domain TPR_11 PF13414.1 EGC33425.1 - 0.21 11.2 4.1 0.24 11.0 1.1 2.4 2 0 0 2 2 2 0 TPR repeat DUF830 PF05708.7 EGC33426.1 - 9.3e-09 35.4 0.0 2.9e-08 33.8 0.0 1.8 2 0 0 2 2 2 1 Orthopoxvirus protein of unknown function (DUF830) DUF1738 PF08401.6 EGC33426.1 - 0.077 12.7 0.1 0.22 11.2 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF1738) zf-TRAF PF02176.13 EGC33427.1 - 0.00055 20.2 41.2 0.0078 16.5 5.5 5.0 3 1 4 7 7 7 4 TRAF-type zinc finger DivIVA PF05103.8 EGC33427.1 - 0.0086 16.1 6.0 0.0086 16.1 4.2 1.7 2 0 0 2 2 2 1 DivIVA protein CorA PF01544.13 EGC33427.1 - 0.033 13.2 0.5 0.049 12.6 0.4 1.2 1 0 0 1 1 1 0 CorA-like Mg2+ transporter protein HAUS6_N PF14661.1 EGC33427.1 - 0.036 13.4 2.0 0.061 12.6 1.0 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus DivIC PF04977.10 EGC33427.1 - 0.052 13.0 5.0 0.15 11.5 3.5 1.8 1 0 0 1 1 1 0 Septum formation initiator bZIP_2 PF07716.10 EGC33427.1 - 0.2 11.5 8.1 0.13 12.1 3.4 1.8 1 1 1 2 2 2 0 Basic region leucine zipper Med4 PF10018.4 EGC33427.1 - 0.21 10.9 2.9 0.36 10.2 2.0 1.3 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Cep57_CLD_2 PF14197.1 EGC33427.1 - 0.48 10.4 7.6 0.078 12.9 2.4 1.8 2 0 0 2 2 2 0 Centrosome localisation domain of PPC89 KIAA1430 PF13879.1 EGC33427.1 - 4.7 7.6 20.0 1e+02 3.4 0.2 3.4 2 1 0 2 2 2 0 KIAA1430 homologue Phage_F PF02305.12 EGC33428.1 - 0.14 10.6 0.4 0.14 10.6 0.3 1.0 1 0 0 1 1 1 0 Capsid protein (F protein) Acetyltransf_7 PF13508.1 EGC33429.1 - 0.042 14.0 0.0 0.069 13.3 0.0 1.4 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain PIG-L PF02585.12 EGC33430.1 - 2.9e-25 89.2 0.0 4.9e-25 88.4 0.0 1.4 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase zf-RING_2 PF13639.1 EGC33431.1 - 1e-15 57.2 9.3 1.4e-15 56.8 6.4 1.2 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC33431.1 - 2.2e-10 40.4 6.1 3.5e-10 39.8 4.2 1.3 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC33431.1 - 5.8e-07 29.4 10.1 8e-07 28.9 7.0 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC33431.1 - 6.2e-06 25.7 10.1 9.6e-06 25.1 7.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC33431.1 - 9.6e-06 25.1 8.2 1.2e-05 24.8 5.7 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33431.1 - 2e-05 24.1 9.1 3e-05 23.6 6.3 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC33431.1 - 0.0034 17.1 5.9 0.0058 16.4 4.1 1.4 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-HC5HC2H_2 PF13832.1 EGC33431.1 - 0.0057 16.6 3.2 0.0068 16.3 2.2 1.2 1 0 0 1 1 1 1 PHD-zinc-finger like domain RINGv PF12906.2 EGC33431.1 - 0.069 13.2 7.6 0.14 12.2 5.3 1.5 1 1 0 1 1 1 0 RING-variant domain zf-Nse PF11789.3 EGC33431.1 - 0.075 12.5 5.3 0.13 11.8 3.7 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FANCL_C PF11793.3 EGC33431.1 - 0.22 11.5 7.6 0.48 10.4 5.3 1.6 1 1 0 1 1 1 0 FANCL C-terminal domain Voltage_CLC PF00654.15 EGC33432.1 - 1.8e-76 257.4 21.2 1.8e-76 257.4 14.7 1.4 1 1 0 1 1 1 1 Voltage gated chloride channel CBS PF00571.23 EGC33432.1 - 3.6e-08 33.0 0.1 0.00016 21.4 0.0 2.4 2 0 0 2 2 2 2 CBS domain Pex14_N PF04695.8 EGC33432.1 - 0.0089 16.0 0.2 0.032 14.2 0.1 1.9 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region GET2 PF08690.5 EGC33432.1 - 9.5 5.3 9.5 20 4.3 6.6 1.5 1 0 0 1 1 1 0 GET complex subunit GET2 DUF2207 PF09972.4 EGC33433.1 - 0.024 13.2 2.8 0.033 12.7 1.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF2244 PF10003.4 EGC33433.1 - 0.075 12.3 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) PLAC8 PF04749.12 EGC33434.1 - 4.4e-08 33.6 9.5 8e-08 32.8 6.6 1.5 1 0 0 1 1 1 1 PLAC8 family DUF1364 PF07102.7 EGC33434.1 - 0.11 12.3 3.1 0.51 10.2 0.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1364) NAD_binding_4 PF07993.7 EGC33435.1 - 5.6e-44 149.9 0.0 9.1e-44 149.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGC33435.1 - 8.7e-06 25.3 0.0 1.9e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC33435.1 - 0.00044 19.2 0.3 0.00088 18.2 0.2 1.5 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein MacB_PCD PF12704.2 EGC33435.1 - 0.0037 16.8 2.2 0.091 12.3 0.4 2.6 2 0 0 2 2 2 1 MacB-like periplasmic core domain EGF_2 PF07974.8 EGC33435.1 - 0.24 11.5 9.0 0.59 10.3 6.3 1.7 1 0 0 1 1 1 0 EGF-like domain ATP12 PF07542.6 EGC33436.1 - 5e-26 91.0 0.0 8.3e-26 90.3 0.0 1.3 1 0 0 1 1 1 1 ATP12 chaperone protein DUF1803 PF08820.5 EGC33436.1 - 0.075 12.7 1.5 0.56 9.9 1.0 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF1803) ox_reductase_C PF08635.5 EGC33436.1 - 0.12 11.7 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 Putative oxidoreductase C terminal YxiJ PF14176.1 EGC33436.1 - 0.13 12.3 3.5 0.19 11.8 0.3 2.4 2 1 0 2 2 2 0 YxiJ-like protein ARL2_Bind_BART PF11527.3 EGC33436.1 - 0.37 10.5 5.2 0.23 11.2 0.4 2.2 2 0 0 2 2 2 0 The ARF-like 2 binding protein BART MTS PF05175.9 EGC33437.1 - 3.1e-19 68.9 0.0 4e-19 68.6 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC33437.1 - 1.4e-10 41.1 0.0 1.9e-10 40.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC33437.1 - 1.6e-10 40.7 0.1 2.6e-10 40.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGC33437.1 - 9.2e-10 38.1 0.0 1.5e-09 37.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_23 PF13489.1 EGC33437.1 - 7.9e-08 32.1 0.0 1.5e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC33437.1 - 3.2e-07 30.9 0.0 5.4e-07 30.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGC33437.1 - 9e-07 28.2 0.0 1.7e-06 27.3 0.0 1.5 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 EGC33437.1 - 1.6e-06 27.8 0.0 2.4e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein RrnaAD PF00398.15 EGC33437.1 - 3.3e-05 23.0 0.0 4.7e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_11 PF08241.7 EGC33437.1 - 0.00018 21.9 0.0 0.00045 20.6 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC33437.1 - 0.00033 20.9 0.0 0.00053 20.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGC33437.1 - 0.00042 19.8 0.0 0.0007 19.0 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_12 PF08242.7 EGC33437.1 - 0.00056 20.3 0.0 0.00098 19.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC33437.1 - 0.014 14.9 0.0 0.021 14.3 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MethyltransfD12 PF02086.10 EGC33437.1 - 0.019 14.4 0.1 0.031 13.7 0.0 1.3 1 0 0 1 1 1 0 D12 class N6 adenine-specific DNA methyltransferase TRM PF02005.11 EGC33437.1 - 0.033 13.1 0.0 0.047 12.5 0.0 1.2 1 0 0 1 1 1 0 N2,N2-dimethylguanosine tRNA methyltransferase N6_N4_Mtase PF01555.13 EGC33437.1 - 0.071 12.5 0.2 2.1 7.7 0.1 2.2 2 0 0 2 2 2 0 DNA methylase TFR_dimer PF04253.10 EGC33437.1 - 0.1 12.1 0.1 0.29 10.7 0.0 1.7 2 0 0 2 2 2 0 Transferrin receptor-like dimerisation domain Palm_thioest PF02089.10 EGC33438.1 - 3e-48 164.1 0.0 3.5e-48 163.9 0.0 1.0 1 0 0 1 1 1 1 Palmitoyl protein thioesterase Abhydrolase_1 PF00561.15 EGC33438.1 - 0.0011 18.5 0.0 0.002 17.7 0.0 1.5 2 0 0 2 2 2 1 alpha/beta hydrolase fold Lipase_2 PF01674.13 EGC33438.1 - 0.0016 17.8 0.0 0.042 13.1 0.0 2.4 1 1 0 1 1 1 1 Lipase (class 2) DUF676 PF05057.9 EGC33438.1 - 0.049 12.9 0.0 0.12 11.6 0.0 1.6 1 1 0 1 1 1 0 Putative serine esterase (DUF676) FSH1 PF03959.8 EGC33438.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGC33438.1 - 0.13 12.0 0.0 0.31 10.8 0.0 1.8 1 1 0 1 1 1 0 Alpha/beta hydrolase family 7tm_2 PF00002.19 EGC33439.1 - 2.7e-24 85.5 14.9 3.3e-24 85.3 10.3 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGC33439.1 - 3.4e-21 75.4 15.4 4.2e-21 75.1 10.7 1.0 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 EGC33439.1 - 2.1e-08 33.1 4.7 2.8e-08 32.7 3.3 1.2 1 0 0 1 1 1 1 Ocular albinism type 1 protein Frizzled PF01534.12 EGC33439.1 - 9.4e-07 27.9 17.0 2.7e-05 23.1 2.7 2.3 1 1 1 2 2 2 2 Frizzled/Smoothened family membrane region PufQ PF05398.6 EGC33439.1 - 0.047 13.7 0.0 0.16 12.0 0.0 1.9 1 0 0 1 1 1 0 PufQ cytochrome subunit Pox_P21 PF05313.7 EGC33439.1 - 0.049 12.8 4.2 1.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein FR47 PF08445.5 EGC33440.1 - 3e-07 30.1 0.0 5.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Gly_acyl_tr_C PF08444.5 EGC33440.1 - 0.0047 16.9 0.2 0.04 13.9 0.0 2.5 3 1 0 3 3 3 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region Acetyltransf_7 PF13508.1 EGC33440.1 - 0.01 15.9 0.0 0.025 14.7 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC33440.1 - 0.014 15.6 0.0 0.033 14.3 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC33440.1 - 0.027 14.5 0.0 0.051 13.6 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Put_DNA-bind_N PF06971.8 EGC33440.1 - 0.032 14.0 0.1 0.081 12.6 0.1 1.7 1 0 0 1 1 1 0 Putative DNA-binding protein N-terminus DPBB_1 PF03330.13 EGC33441.1 - 6.6e-10 38.8 0.4 6.6e-10 38.8 0.2 2.0 2 1 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel LysM PF01476.15 EGC33441.1 - 1.8e-09 37.3 1.5 0.0014 18.4 0.2 2.6 2 0 0 2 2 2 2 LysM domain RabGAP-TBC PF00566.13 EGC33444.1 - 1.3e-37 129.4 7.5 1.6e-37 129.0 5.2 1.1 1 0 0 1 1 1 1 Rab-GTPase-TBC domain CCDC50_N PF15295.1 EGC33444.1 - 0.011 15.6 3.0 0.02 14.8 2.1 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 50 N-terminus BAR PF03114.13 EGC33445.1 - 1.2e-21 77.2 6.8 1.9e-21 76.6 4.7 1.1 1 0 0 1 1 1 1 BAR domain SH3_9 PF14604.1 EGC33445.1 - 2.8e-11 42.8 0.0 4.9e-11 42.0 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC33445.1 - 1.2e-09 37.4 0.0 2.6e-09 36.3 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC33445.1 - 4.4e-06 26.0 0.0 8.5e-06 25.1 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain TPR_MLP1_2 PF07926.7 EGC33445.1 - 0.013 15.2 7.0 0.034 13.8 0.9 2.4 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein Arfaptin PF06456.8 EGC33445.1 - 0.11 11.7 8.5 0.25 10.6 0.3 2.2 2 0 0 2 2 2 0 Arfaptin-like domain FadA PF09403.5 EGC33445.1 - 0.22 11.5 8.8 0.36 10.8 1.1 2.4 1 1 1 2 2 2 0 Adhesion protein FadA GreA_GreB_N PF03449.10 EGC33445.1 - 2 8.4 7.0 11 6.1 0.4 3.4 3 1 0 3 3 3 0 Transcription elongation factor, N-terminal CBM49 PF09478.5 EGC33446.1 - 5.6e-15 55.2 0.2 7.9e-15 54.7 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC33446.1 - 0.18 11.8 1.8 0.42 10.5 0.3 2.1 2 0 0 2 2 2 0 DIM protein TRAP_alpha PF03896.11 EGC33447.1 - 1.8e-31 109.2 1.3 2.2e-31 108.9 0.9 1.1 1 0 0 1 1 1 1 Translocon-associated protein (TRAP), alpha subunit DUF4366 PF14283.1 EGC33447.1 - 0.0099 15.3 0.0 0.022 14.1 0.0 1.6 2 0 0 2 2 2 1 Domain of unknown function (DUF4366) SpoIIIAH PF12685.2 EGC33447.1 - 0.03 13.8 0.2 0.38 10.2 0.0 2.1 2 0 0 2 2 2 0 SpoIIIAH-like protein FixQ PF05545.6 EGC33447.1 - 0.11 12.1 3.3 9.3 5.9 0.0 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ PRK PF00485.13 EGC33448.1 - 7.2e-25 87.6 1.3 4.9e-24 84.9 0.9 2.0 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.16 EGC33448.1 - 3.8e-11 42.9 0.0 5.9e-11 42.3 0.0 1.2 1 0 0 1 1 1 1 CYTH domain AAA_17 PF13207.1 EGC33448.1 - 6.8e-07 30.1 0.1 3.2e-06 27.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC33448.1 - 9.2e-05 22.7 0.4 0.00026 21.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC33448.1 - 0.00069 18.7 0.1 0.0041 16.2 0.0 2.1 2 0 0 2 2 2 1 Zeta toxin AAA_33 PF13671.1 EGC33448.1 - 0.0032 17.3 0.0 0.0062 16.4 0.0 1.5 1 1 0 1 1 1 1 AAA domain NACHT PF05729.7 EGC33448.1 - 0.0039 16.8 0.0 0.012 15.2 0.0 1.8 2 0 0 2 2 2 1 NACHT domain NTPase_1 PF03266.10 EGC33448.1 - 0.0052 16.5 0.1 0.2 11.3 0.1 2.5 2 0 0 2 2 2 1 NTPase AAA_24 PF13479.1 EGC33448.1 - 0.0076 15.8 0.0 0.014 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGC33448.1 - 0.009 14.8 0.2 0.018 13.8 0.2 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_16 PF13191.1 EGC33448.1 - 0.0099 15.8 0.0 0.018 15.0 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGC33448.1 - 0.01 15.5 0.2 0.035 13.8 0.0 2.0 2 0 0 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EGC33448.1 - 0.018 15.3 0.0 0.043 14.1 0.0 1.7 1 0 0 1 1 1 0 ABC transporter DUF258 PF03193.11 EGC33448.1 - 0.019 14.1 0.1 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGC33448.1 - 0.029 14.6 4.2 0.32 11.2 0.3 3.0 2 1 0 2 2 2 0 AAA domain MobB PF03205.9 EGC33448.1 - 0.033 13.9 0.2 0.13 11.9 0.1 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Mg_chelatase PF01078.16 EGC33448.1 - 0.033 13.3 0.0 0.065 12.3 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EGC33448.1 - 0.033 13.8 0.0 0.082 12.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Guanylate_kin PF00625.16 EGC33448.1 - 0.033 13.6 0.0 0.074 12.4 0.0 1.5 1 0 0 1 1 1 0 Guanylate kinase RNA_helicase PF00910.17 EGC33448.1 - 0.037 14.1 0.1 1.1 9.4 0.0 2.6 2 0 0 2 2 2 0 RNA helicase KAP_NTPase PF07693.9 EGC33448.1 - 0.049 12.6 0.0 0.058 12.3 0.0 1.3 1 0 0 1 1 1 0 KAP family P-loop domain AAA_22 PF13401.1 EGC33448.1 - 0.051 13.7 0.0 0.16 12.1 0.0 2.0 2 0 0 2 2 1 0 AAA domain ATP-grasp_2 PF08442.5 EGC33448.1 - 0.076 12.3 0.0 0.18 11.1 0.0 1.6 2 0 0 2 2 1 0 ATP-grasp domain AAA PF00004.24 EGC33448.1 - 0.086 13.0 0.1 0.36 11.0 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) T2SE PF00437.15 EGC33448.1 - 0.087 11.7 0.0 0.16 10.8 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein ArgK PF03308.11 EGC33448.1 - 0.12 11.1 0.1 0.21 10.3 0.1 1.3 1 0 0 1 1 1 0 ArgK protein AAA_5 PF07728.9 EGC33448.1 - 0.12 12.0 0.0 0.38 10.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGC33448.1 - 0.21 11.3 0.2 0.45 10.2 0.1 1.5 1 0 0 1 1 1 0 Part of AAA domain AAR2 PF05282.6 EGC33449.1 - 9.9e-87 291.1 13.8 9.9e-87 291.1 9.6 1.8 1 1 1 2 2 2 1 AAR2 protein DUF778 PF05608.7 EGC33449.1 - 0.0078 16.1 0.4 0.053 13.4 0.3 2.5 1 1 0 1 1 1 1 Protein of unknown function (DUF778) DUF1162 PF06650.7 EGC33451.1 - 8.8e-46 156.3 7.3 8.8e-46 156.3 5.1 6.2 5 2 2 7 7 7 3 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGC33451.1 - 4.9e-31 106.7 0.1 4.9e-31 106.7 0.1 5.0 3 1 1 4 4 4 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC33451.1 - 6.5e-05 23.0 0.0 0.00024 21.2 0.0 2.0 1 0 0 1 1 1 1 ATG C terminal domain VIT1 PF01988.14 EGC33452.1 - 0.24 10.8 1.4 0.43 10.0 1.0 1.3 1 0 0 1 1 1 0 VIT family DNA_pol3_delta2 PF13177.1 EGC33453.1 - 0.091 12.4 0.2 0.094 12.3 0.1 1.2 1 0 0 1 1 1 0 DNA polymerase III, delta subunit PIG-X PF08320.7 EGC33454.1 - 7e-26 90.7 0.9 1.7e-25 89.5 0.6 1.7 1 0 0 1 1 1 1 PIG-X / PBN1 Glyco_hydro_9 PF00759.14 EGC33455.1 - 3.4e-125 418.4 11.2 3.9e-125 418.2 7.8 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 EABR PF12180.3 EGC33455.1 - 0.25 10.6 1.7 0.53 9.6 1.2 1.5 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 AF-4 PF05110.8 EGC33455.1 - 1.6 6.5 4.5 2.1 6.1 3.1 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein GST_N_2 PF13409.1 EGC33457.1 - 8e-23 80.2 0.0 2.9e-22 78.4 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC33457.1 - 8.4e-14 51.2 0.0 1.5e-13 50.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC33457.1 - 4.9e-10 39.2 0.0 8.2e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC33457.1 - 5.2e-07 29.7 0.0 4.9e-06 26.6 0.0 2.4 2 1 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC33457.1 - 4.1e-06 27.1 0.0 6.5e-06 26.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Lectin_legB PF00139.14 EGC33458.1 - 1.7e-17 63.5 3.4 1.7e-17 63.5 2.3 1.8 1 1 1 2 2 2 1 Legume lectin domain Lectin_leg-like PF03388.8 EGC33458.1 - 0.0005 19.2 3.3 0.15 11.1 0.0 2.5 2 1 0 2 2 2 2 Legume-like lectin family Abhydrolase_3 PF07859.8 EGC33459.1 - 5.1e-13 49.0 0.0 8e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC33459.1 - 7.1e-12 45.2 0.0 9.9e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC33459.1 - 3.2e-05 23.2 0.0 0.0064 15.7 0.0 2.2 2 0 0 2 2 2 2 Prolyl oligopeptidase family COesterase PF00135.23 EGC33459.1 - 0.00041 19.1 0.5 0.0011 17.7 0.3 1.7 1 1 0 1 1 1 1 Carboxylesterase family DUF2305 PF10230.4 EGC33459.1 - 0.002 17.6 1.3 0.0058 16.0 0.1 2.1 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) PGAP1 PF07819.8 EGC33459.1 - 0.0048 16.5 0.0 0.01 15.4 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_6 PF12697.2 EGC33459.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Lipase_3 PF01764.20 EGC33459.1 - 0.0069 16.0 0.0 0.021 14.4 0.0 1.9 1 1 0 1 1 1 1 Lipase (class 3) GYD PF08734.6 EGC33459.1 - 0.0078 15.9 0.0 0.016 14.9 0.0 1.4 1 0 0 1 1 1 1 GYD domain Peptidase_M9_N PF08453.5 EGC33459.1 - 0.014 14.7 0.6 0.094 12.0 0.4 2.2 1 1 0 1 1 1 0 Peptidase family M9 N-terminal DUF676 PF05057.9 EGC33459.1 - 0.03 13.6 0.1 0.044 13.0 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Chlorophyllase2 PF12740.2 EGC33459.1 - 0.037 12.8 0.1 0.077 11.8 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase enzyme GTP_EFTU PF00009.22 EGC33460.1 - 1.2e-38 132.4 0.0 2e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGC33460.1 - 2.9e-24 84.9 0.0 1.1e-23 83.0 0.0 2.0 2 0 0 2 2 2 1 Elongation factor G, domain IV EFG_C PF00679.19 EGC33460.1 - 1.4e-19 69.7 0.0 9.9e-19 67.0 0.0 2.3 2 0 0 2 2 2 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC33460.1 - 3.4e-08 33.4 0.0 7.3e-08 32.4 0.0 1.6 1 0 0 1 1 1 1 Elongation factor Tu domain 2 EFG_II PF14492.1 EGC33460.1 - 2.2e-07 30.6 0.0 5.4e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Elongation Factor G, domain II MMR_HSR1 PF01926.18 EGC33460.1 - 0.0011 18.9 0.0 0.0026 17.6 0.0 1.7 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_10 PF12846.2 EGC33460.1 - 0.02 14.3 0.0 0.033 13.6 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain Miro PF08477.8 EGC33460.1 - 0.023 15.2 0.0 0.066 13.7 0.0 1.9 1 0 0 1 1 1 0 Miro-like protein Astro_capsid PF03115.9 EGC33460.1 - 7.1 4.7 7.1 1.2 7.3 2.1 1.6 1 1 1 2 2 2 0 Astrovirus capsid protein precursor Chordopox_A33R PF05966.7 EGC33461.1 - 0.011 14.5 3.2 0.013 14.2 2.2 1.1 1 0 0 1 1 1 0 Chordopoxvirus A33R protein TAF1_subA PF14929.1 EGC33461.1 - 0.14 10.5 2.0 0.17 10.2 1.0 1.3 1 1 0 1 1 1 0 TAF RNA Polymerase I subunit A PH PF00169.24 EGC33462.1 - 4.5e-13 49.2 0.1 4.5e-13 49.2 0.0 2.0 2 1 0 2 2 2 1 PH domain S_layer_N PF05123.7 EGC33462.1 - 0.004 16.8 2.5 0.0052 16.4 1.8 1.2 1 0 0 1 1 1 1 S-layer like family, N-terminal region PH_11 PF15413.1 EGC33462.1 - 0.0059 16.8 9.8 0.012 15.8 0.3 3.3 2 2 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGC33462.1 - 0.024 14.7 2.2 0.062 13.4 0.1 2.5 2 1 0 2 2 2 0 Pleckstrin homology domain DSPc PF00782.15 EGC33463.1 - 8.6e-26 90.0 4.3 8.6e-26 90.0 3.0 3.4 2 2 0 2 2 2 1 Dual specificity phosphatase, catalytic domain CDKN3 PF05706.7 EGC33463.1 - 0.053 12.9 0.0 0.092 12.1 0.0 1.4 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor 3 (CDKN3) Neur_chan_memb PF02932.11 EGC33463.1 - 0.13 12.1 5.7 0.28 11.0 2.8 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region PTPlike_phytase PF14566.1 EGC33463.1 - 0.57 10.2 8.5 3.6 7.6 5.9 2.2 1 1 0 1 1 1 0 Inositol hexakisphosphate G-alpha PF00503.15 EGC33464.1 - 2.9e-108 362.0 8.9 4.6e-108 361.3 6.2 1.2 1 1 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC33464.1 - 5.9e-16 58.2 1.1 2.9e-11 42.9 0.2 2.6 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC33464.1 - 0.0001 21.5 1.1 0.039 13.0 0.1 2.3 2 0 0 2 2 2 2 Gtr1/RagA G protein conserved region CPT PF07931.7 EGC33464.1 - 0.00035 20.2 0.0 0.0017 18.0 0.0 2.0 2 0 0 2 2 2 1 Chloramphenicol phosphotransferase-like protein Miro PF08477.8 EGC33464.1 - 0.00079 19.9 0.1 1.6 9.2 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein Ras PF00071.17 EGC33464.1 - 0.0023 17.3 1.7 0.72 9.2 0.2 2.5 2 1 0 2 2 2 2 Ras family Phage_pRha PF09669.5 EGC33464.1 - 0.046 14.0 0.3 0.47 10.8 0.0 2.7 3 0 0 3 3 3 0 Phage regulatory protein Rha (Phage_pRha) GTP_EFTU PF00009.22 EGC33464.1 - 0.06 12.7 0.4 2.7 7.3 0.0 2.7 3 0 0 3 3 3 0 Elongation factor Tu GTP binding domain Pex14_N PF04695.8 EGC33464.1 - 0.13 12.2 0.0 0.34 10.9 0.0 1.6 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region zf-RING_2 PF13639.1 EGC33467.1 - 9e-09 35.0 8.1 1.6e-08 34.2 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC33467.1 - 2.5e-07 30.2 11.4 7e-07 28.8 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC33467.1 - 1.9e-06 27.4 7.1 3.2e-06 26.6 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33467.1 - 2.6e-05 24.1 10.6 5.5e-05 23.1 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33467.1 - 5.8e-05 23.1 4.5 0.00019 21.4 3.1 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC33467.1 - 0.0084 15.9 9.7 0.019 14.8 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC33467.1 - 0.0091 15.6 9.5 0.019 14.7 6.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC33467.1 - 0.035 13.7 8.1 0.068 12.7 5.6 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC33467.1 - 0.2 11.3 6.8 0.86 9.3 4.7 2.2 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC33467.1 - 1.5 8.7 6.7 2.9 7.7 4.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) XRN_N PF03159.13 EGC33468.1 - 1.5e-67 227.4 0.1 2.9e-67 226.5 0.0 1.5 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus PITH PF06201.8 EGC33468.1 - 5.3e-23 81.4 6.7 1.4e-22 80.0 4.7 1.8 1 0 0 1 1 1 1 PITH domain RRM_1 PF00076.17 EGC33468.1 - 2.9e-17 62.0 2.3 6.9e-09 35.2 0.1 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC33468.1 - 9.9e-15 54.2 0.1 3e-07 30.3 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC33468.1 - 1.8e-08 34.0 1.5 1.4e-05 24.8 0.2 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC_3 PF13917.1 EGC33468.1 - 0.00019 21.1 0.3 0.00045 19.8 0.2 1.6 1 0 0 1 1 1 1 Zinc knuckle APG5 PF04106.7 EGC33469.1 - 7e-60 201.8 1.1 9.6e-60 201.4 0.7 1.2 1 0 0 1 1 1 1 Autophagy protein Apg5 HhH-GPD PF00730.20 EGC33470.1 - 0.0062 16.8 0.0 0.0065 16.7 0.0 1.2 1 0 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein EndIII_4Fe-2S PF10576.4 EGC33470.1 - 0.064 13.4 1.6 0.15 12.3 1.1 1.6 1 0 0 1 1 1 0 Iron-sulfur binding domain of endonuclease III ketoacyl-synt PF00109.21 EGC33471.1 - 1.4e-60 204.9 0.0 2e-60 204.4 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC33471.1 - 7.6e-51 173.3 0.0 1.1e-50 172.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC33471.1 - 1.7e-44 151.5 0.0 3.5e-44 150.6 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC33471.1 - 2.2e-29 101.7 0.0 4.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC33471.1 - 2.1e-21 76.2 0.0 1.3e-20 73.6 0.0 2.6 1 0 0 1 1 1 1 Methyltransferase domain KR PF08659.5 EGC33471.1 - 5.7e-20 71.7 0.0 1.2e-19 70.7 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC33471.1 - 2.5e-17 62.9 0.0 3.9e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC33471.1 - 1.3e-12 47.9 0.0 3.1e-11 43.4 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC33471.1 - 1.1e-09 38.2 0.0 3.1e-09 36.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC33471.1 - 1.2e-08 35.9 0.0 3.4e-08 34.4 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EGC33471.1 - 3.3e-07 30.6 0.0 1.4e-06 28.7 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EGC33471.1 - 5.2e-05 22.7 0.0 0.0023 17.4 0.0 2.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGC33471.1 - 0.00025 21.2 0.8 0.00057 20.0 0.6 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC33471.1 - 0.00037 19.5 0.1 0.00095 18.2 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.19 EGC33471.1 - 0.021 15.1 0.0 3.7 7.8 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain EGF_2 PF07974.8 EGC33472.1 - 0.0015 18.6 9.1 0.0015 18.6 6.3 2.7 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC33472.1 - 2.4 8.4 7.0 0.24 11.5 0.8 2.4 2 0 0 2 2 2 0 Human growth factor-like EGF AMP-binding PF00501.23 EGC33474.1 - 1e-67 228.3 0.0 1.2e-67 228.0 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Actin PF00022.14 EGC33475.1 - 8.1e-163 541.4 0.0 9.2e-163 541.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC33475.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) adh_short PF00106.20 EGC33476.1 - 3.6e-29 101.8 0.0 5.5e-29 101.2 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC33476.1 - 1.6e-12 47.6 0.0 2.2e-12 47.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC33476.1 - 5.1e-11 42.5 0.2 1.6e-07 31.1 0.0 2.2 2 0 0 2 2 2 2 KR domain NAD_binding_10 PF13460.1 EGC33476.1 - 5.6e-06 26.4 0.0 0.00054 20.0 0.0 2.2 2 0 0 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGC33476.1 - 8.8e-06 25.3 0.1 1.9e-05 24.2 0.1 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3HCDH_N PF02737.13 EGC33476.1 - 0.00042 20.0 0.1 0.00069 19.3 0.1 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Polysacc_synt_2 PF02719.10 EGC33476.1 - 0.00076 18.4 0.1 0.0013 17.7 0.1 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EGC33476.1 - 0.0022 16.9 0.0 0.58 9.0 0.0 2.1 2 0 0 2 2 2 2 Male sterility protein Pyr_redox PF00070.22 EGC33476.1 - 0.0091 16.3 0.1 0.02 15.2 0.0 1.6 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGC33476.1 - 0.016 14.4 0.0 0.022 13.8 0.0 1.2 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ELFV_dehydrog PF00208.16 EGC33476.1 - 0.031 13.8 0.0 0.057 12.9 0.0 1.4 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Spc7 PF08317.6 EGC33476.1 - 0.04 12.5 0.4 0.083 11.5 0.1 1.6 2 0 0 2 2 2 0 Spc7 kinetochore protein ApbA PF02558.11 EGC33476.1 - 0.051 13.0 0.0 0.079 12.4 0.0 1.3 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA DUF2203 PF09969.4 EGC33476.1 - 0.063 13.4 0.3 1.4 9.1 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) TcpQ PF10671.4 EGC33476.1 - 0.077 12.8 0.0 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q zf-MIZ PF02891.15 EGC33477.1 - 2.2e-20 71.9 3.8 3.9e-20 71.0 2.7 1.4 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-Nse PF11789.3 EGC33477.1 - 3.2e-06 26.5 0.8 6.9e-06 25.4 0.6 1.6 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit TRAPPC9-Trs120 PF08626.6 EGC33478.1 - 1.7e-122 409.9 29.3 2.1e-122 409.6 20.3 1.1 1 0 0 1 1 1 1 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit DUF2067 PF09840.4 EGC33478.1 - 0.031 13.7 0.2 0.28 10.6 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2067) Foie-gras_1 PF11817.3 EGC33478.1 - 0.11 11.9 0.0 0.59 9.5 0.0 2.1 2 0 0 2 2 2 0 Foie gras liver health family 1 DUF4389 PF14333.1 EGC33479.1 - 0.023 14.4 1.5 0.042 13.5 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4389) Oxidored_q3 PF00499.15 EGC33479.1 - 0.034 13.9 1.4 1 9.1 0.1 2.2 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF4234 PF14018.1 EGC33479.1 - 0.058 13.1 0.5 0.1 12.3 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4448 PF14610.1 EGC33479.1 - 0.081 12.4 0.2 0.11 12.0 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF4448) DUF4131 PF13567.1 EGC33479.1 - 0.088 12.2 0.0 0.28 10.5 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF2232 PF09991.4 EGC33479.1 - 0.61 9.0 3.2 0.45 9.4 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) DUF2149 PF09919.4 EGC33479.1 - 0.89 9.6 8.8 0.088 12.9 0.7 2.7 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2149) ETRAMP PF09716.5 EGC33479.1 - 3.7 7.5 15.8 0.41 10.6 2.3 2.7 2 1 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) CfAFP PF05264.6 EGC33479.1 - 4.7 6.9 5.2 3.2 7.5 0.4 2.1 1 1 1 2 2 2 0 Choristoneura fumiferana antifreeze protein (CfAFP) Amnionless PF14828.1 EGC33480.1 - 0.022 13.2 0.0 0.039 12.4 0.0 1.3 1 0 0 1 1 1 0 Amnionless MtrF PF09472.5 EGC33480.1 - 0.056 12.6 1.2 0.11 11.7 0.8 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) SKG6 PF08693.5 EGC33480.1 - 4.8 6.5 8.2 0.55 9.5 2.6 1.7 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Gly_acyl_tr_C PF08444.5 EGC33481.1 - 3.7e-05 23.6 0.0 9.9e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region FR47 PF08445.5 EGC33481.1 - 4.3e-05 23.1 0.0 0.0001 21.9 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGC33481.1 - 0.0034 17.4 0.0 0.013 15.6 0.0 1.9 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain PLA2_B PF01735.13 EGC33481.1 - 0.016 13.4 1.0 0.023 12.8 0.1 1.6 2 0 0 2 2 2 0 Lysophospholipase catalytic domain Acetyltransf_7 PF13508.1 EGC33481.1 - 0.074 13.2 0.0 0.18 12.0 0.0 1.7 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC33481.1 - 0.085 13.0 0.0 0.21 11.7 0.0 1.8 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF592 PF04574.8 EGC33481.1 - 0.82 9.2 5.4 0.21 11.1 0.7 2.1 2 1 0 2 2 2 0 Protein of unknown function (DUF592) Actin PF00022.14 EGC33482.1 - 8.1e-163 541.4 0.0 9.2e-163 541.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC33482.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) SH3_2 PF07653.12 EGC33485.1 - 5e-10 38.7 0.0 7.3e-10 38.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGC33485.1 - 1.1e-05 24.8 0.1 1.1e-05 24.8 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain DUF1510 PF07423.6 EGC33487.1 - 0.0014 18.0 18.4 0.0014 18.0 12.7 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF1510) MIP-T3 PF10243.4 EGC33487.1 - 0.54 8.6 46.6 0.71 8.2 32.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EGC33487.1 - 2.8 5.9 48.8 4 5.4 33.8 1.1 1 0 0 1 1 1 0 Utp14 protein AA_permease_2 PF13520.1 EGC33488.1 - 1.3e-36 126.0 47.8 1.7e-36 125.7 33.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC33488.1 - 3.1e-24 85.1 36.4 3.9e-24 84.8 25.2 1.1 1 0 0 1 1 1 1 Amino acid permease Baculo_11_kDa PF06143.6 EGC33488.1 - 0.61 9.4 4.6 27 4.2 0.0 3.8 3 1 0 3 3 3 0 Baculovirus 11 kDa family MBOAT PF03062.14 EGC33489.1 - 4.8e-25 88.3 22.2 9.6e-25 87.3 15.4 1.4 1 0 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family MBOAT_2 PF13813.1 EGC33489.1 - 0.00011 22.2 7.6 0.00023 21.1 5.3 1.5 1 0 0 1 1 1 1 Membrane bound O-acyl transferase family Period_C PF12114.3 EGC33489.1 - 1.7 8.1 6.2 2.6 7.5 4.3 1.2 1 0 0 1 1 1 0 Period protein 2/3C-terminal region PRK PF00485.13 EGC33490.1 - 9.1e-15 54.7 1.9 3.8e-13 49.4 1.3 2.3 1 1 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family CYTH PF01928.16 EGC33490.1 - 1.2e-14 54.3 0.0 2.1e-14 53.6 0.0 1.4 1 0 0 1 1 1 1 CYTH domain AAA_17 PF13207.1 EGC33490.1 - 1.1e-05 26.2 0.1 3.4e-05 24.6 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC33490.1 - 0.0049 17.1 0.1 0.0049 17.1 0.1 2.2 2 0 0 2 2 2 1 AAA domain Homeobox PF00046.24 EGC33490.1 - 0.0067 16.0 0.2 0.02 14.4 0.0 1.9 1 1 0 1 1 1 1 Homeobox domain ABC_tran PF00005.22 EGC33490.1 - 0.021 15.1 2.0 0.052 13.8 1.4 2.0 1 1 0 1 1 1 0 ABC transporter NB-ARC PF00931.17 EGC33490.1 - 0.023 13.5 0.0 0.044 12.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain ArgK PF03308.11 EGC33490.1 - 0.069 11.9 0.1 0.12 11.1 0.1 1.3 1 0 0 1 1 1 0 ArgK protein Zeta_toxin PF06414.7 EGC33490.1 - 0.078 12.0 0.3 0.16 11.0 0.0 1.6 2 0 0 2 2 2 0 Zeta toxin Nodulin_late PF07127.6 EGC33492.1 - 0.011 15.7 0.3 0.011 15.7 0.2 1.8 2 0 0 2 2 2 0 Late nodulin protein GSG-1 PF07803.6 EGC33492.1 - 0.2 11.2 1.8 0.23 11.0 0.2 1.7 1 1 1 2 2 2 0 GSG1-like protein Prokineticin PF06607.6 EGC33492.1 - 0.31 11.1 3.1 0.46 10.6 2.2 1.3 1 0 0 1 1 1 0 Prokineticin Metallothi_Euk2 PF12809.2 EGC33492.1 - 0.31 11.4 6.4 0.4 11.1 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic metallothionein POP1 PF06978.6 EGC33493.1 - 1.6e-44 151.8 20.2 1.6e-43 148.5 12.2 2.8 2 1 0 2 2 2 1 Ribonucleases P/MRP protein subunit POP1 POPLD PF08170.7 EGC33493.1 - 6e-27 93.3 0.2 6e-27 93.3 0.2 2.2 2 0 0 2 2 2 1 POPLD (NUC188) domain GCV_T PF01571.16 EGC33493.1 - 6.7e-06 25.6 0.0 0.024 14.0 0.0 2.8 3 0 0 3 3 3 2 Aminomethyltransferase folate-binding domain EB PF01683.13 EGC33494.1 - 3.6e-05 23.7 27.0 0.036 14.1 3.5 3.5 1 1 2 3 3 3 3 EB module Dickkopf_N PF04706.7 EGC33494.1 - 2.4 8.4 24.8 0.19 11.9 6.1 3.3 2 1 1 3 3 3 0 Dickkopf N-terminal cysteine-rich region DUF2431 PF10354.4 EGC33495.1 - 1.5e-18 67.2 4.3 2.1e-11 44.0 0.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF2431) Transglut_core PF01841.14 EGC33496.1 - 3.9e-22 78.5 0.0 7.7e-11 42.2 0.0 2.6 2 0 0 2 2 2 2 Transglutaminase-like superfamily DUF853 PF05872.7 EGC33496.1 - 2.7 6.2 6.4 4.6 5.4 4.4 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) TBCA PF02970.11 EGC33497.1 - 4.8e-20 71.4 2.2 6.2e-20 71.0 1.5 1.1 1 0 0 1 1 1 1 Tubulin binding cofactor A DUF724 PF05266.9 EGC33497.1 - 0.057 13.0 3.1 0.067 12.8 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF724) ACOX PF01756.14 EGC33499.1 - 4.7e-16 58.7 0.2 8.4e-16 57.8 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGC33499.1 - 2.9e-09 36.2 0.0 5.9e-09 35.3 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGC33499.1 - 0.00013 22.1 0.0 0.00036 20.6 0.0 1.8 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_ox_N PF14749.1 EGC33499.1 - 0.00044 20.5 0.0 0.0011 19.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal DUF3584 PF12128.3 EGC33500.1 - 0.0051 14.2 27.2 0.0068 13.8 18.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) bZIP_1 PF00170.16 EGC33500.1 - 0.033 14.1 6.5 0.033 14.1 4.5 4.2 2 1 2 4 4 4 0 bZIP transcription factor Nup54 PF13874.1 EGC33500.1 - 0.92 9.1 17.4 0.69 9.5 10.2 2.1 1 1 0 1 1 1 0 Nucleoporin complex subunit 54 HalX PF08663.5 EGC33500.1 - 1.1 9.2 8.1 1.1 9.2 2.7 2.7 1 1 1 2 2 2 0 HalX domain HAUS6_N PF14661.1 EGC33500.1 - 1.9 7.7 25.2 1 8.6 13.2 2.9 1 1 2 3 3 3 0 HAUS augmin-like complex subunit 6 N-terminus HrpB7 PF09486.5 EGC33500.1 - 2.8 7.8 10.9 5.8 6.8 7.6 1.4 1 1 0 1 1 1 0 Bacterial type III secretion protein (HrpB7) LIM PF00412.17 EGC33501.1 - 2.3e-32 110.8 33.6 7.9e-13 48.2 3.6 3.0 3 0 0 3 3 3 3 LIM domain Zn_Tnp_IS1595 PF12760.2 EGC33501.1 - 0.019 14.7 0.4 0.019 14.7 0.3 4.5 4 1 0 4 4 4 0 Transposase zinc-ribbon domain Cmc1 PF08583.5 EGC33501.1 - 0.023 14.4 1.4 0.054 13.2 1.0 1.7 1 0 0 1 1 1 0 Cytochrome c oxidase biogenesis protein Cmc1 like zf-met PF12874.2 EGC33501.1 - 7.6 6.8 14.2 7.8 6.8 0.2 4.7 4 0 0 4 4 4 0 Zinc-finger of C2H2 type Iso_dh PF00180.15 EGC33503.1 - 8.7e-102 340.6 0.1 1.1e-101 340.3 0.1 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase PdxA PF04166.7 EGC33503.1 - 0.035 13.3 0.0 0.086 12.0 0.0 1.6 1 0 0 1 1 1 0 Pyridoxal phosphate biosynthetic protein PdxA OTU PF02338.14 EGC33504.1 - 3.6e-11 43.7 0.0 8.4e-11 42.5 0.0 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease PSD2 PF07624.6 EGC33504.1 - 0.076 12.6 0.0 0.14 11.8 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1585) CHCH PF06747.8 EGC33505.1 - 1.3e-05 24.9 1.3 1.6e-05 24.6 0.9 1.2 1 0 0 1 1 1 1 CHCH domain DUF1903 PF08991.5 EGC33505.1 - 0.021 14.9 0.6 0.028 14.5 0.4 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Amino_oxidase PF01593.19 EGC33507.1 - 9e-11 41.5 0.0 2.6e-10 39.9 0.0 1.7 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC33507.1 - 5.7e-08 32.6 0.0 1.4e-07 31.4 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGC33507.1 - 0.0042 16.8 0.0 0.076 12.7 0.0 2.2 2 0 0 2 2 2 1 FAD-NAD(P)-binding DAO PF01266.19 EGC33507.1 - 0.092 11.6 0.0 0.15 10.9 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase Apis_Csd PF11671.3 EGC33508.1 - 3.4 7.4 10.6 6.4 6.5 7.4 1.4 1 0 0 1 1 1 0 Complementary sex determiner protein WRC PF08879.5 EGC33509.1 - 0.052 13.2 8.8 1.2 8.7 1.3 3.8 3 1 0 3 3 3 0 WRC zf-TRM13_CCCH PF11722.3 EGC33509.1 - 0.072 12.4 6.5 1.9 7.9 0.1 3.7 3 0 0 3 3 3 0 CCCH zinc finger in TRM13 protein EB PF01683.13 EGC33509.1 - 1.2 9.2 15.5 2.1 8.4 0.3 3.3 2 1 1 3 3 3 0 EB module CFEM PF05730.6 EGC33509.1 - 1.2 9.0 12.7 0.31 10.8 4.6 2.6 2 1 0 2 2 2 0 CFEM domain DEAD PF00270.24 EGC33510.1 - 1.5e-46 157.9 0.1 7.1e-44 149.2 0.0 2.4 2 0 0 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC33510.1 - 1.3e-20 73.0 0.0 4.3e-20 71.3 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGC33510.1 - 2.2e-16 59.1 0.4 5.5e-16 57.8 0.3 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) RNase_PH PF01138.16 EGC33511.1 - 4.4e-36 124.1 0.3 5.9e-36 123.7 0.2 1.2 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGC33511.1 - 0.00011 22.0 0.1 0.00025 20.8 0.0 1.6 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 EGF_2 PF07974.8 EGC33512.1 - 0.0006 19.9 10.1 0.0006 19.9 7.0 3.1 2 0 0 2 2 2 1 EGF-like domain LRR_1 PF00560.28 EGC33512.1 - 0.034 14.1 2.0 0.99 9.6 0.1 4.1 2 1 1 3 3 3 0 Leucine Rich Repeat Calcipressin PF04847.7 EGC33513.1 - 3.3e-14 52.9 0.5 7.5e-14 51.7 0.3 1.7 1 1 0 1 1 1 1 Calcipressin CENP-M PF11111.3 EGC33513.1 - 0.01 15.0 0.8 2.8 7.1 0.0 2.4 2 0 0 2 2 2 0 Centromere protein M (CENP-M) Aminotran_1_2 PF00155.16 EGC33514.1 - 1.2e-51 175.8 0.0 1.5e-51 175.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGC33514.1 - 8.8e-05 21.7 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGC33514.1 - 0.0025 16.6 0.0 0.0038 16.0 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Rad60-SLD PF11976.3 EGC33515.1 - 0.00016 21.2 0.0 0.00084 18.9 0.0 2.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like p450 PF00067.17 EGC33516.1 - 6.7e-48 163.3 0.1 8.4e-48 163.0 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Band_7 PF01145.20 EGC33516.1 - 0.024 14.5 0.1 0.047 13.6 0.1 1.7 1 1 0 1 1 1 0 SPFH domain / Band 7 family Copine PF07002.11 EGC33517.1 - 5.3e-46 155.9 0.1 8.6e-46 155.2 0.1 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 EGC33517.1 - 6.1e-23 80.4 0.0 1.1e-12 47.6 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC33517.1 - 2.3e-08 34.1 0.0 4.4e-08 33.1 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC33517.1 - 2.8e-05 23.8 0.1 4.7e-05 23.1 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC33517.1 - 0.00012 22.2 0.0 0.00021 21.4 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_3 PF13768.1 EGC33517.1 - 0.076 12.7 0.0 0.13 11.9 0.0 1.3 1 0 0 1 1 1 0 von Willebrand factor type A domain OTU PF02338.14 EGC33518.1 - 2.7e-12 47.3 0.4 5.2e-12 46.4 0.1 1.7 2 0 0 2 2 2 1 OTU-like cysteine protease DUF3759 PF12585.3 EGC33518.1 - 0.026 14.4 0.0 0.77 9.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3759) FNIP PF05725.7 EGC33520.1 - 5.3e-57 189.5 64.7 1.7e-13 50.2 0.2 9.0 7 2 2 9 9 9 8 FNIP Repeat Ank_2 PF12796.2 EGC33522.1 - 0.046 14.0 0.0 0.18 12.1 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (3 copies) FNIP PF05725.7 EGC33523.1 - 2.1e-45 152.3 56.5 4.5e-09 36.1 4.1 8.1 5 2 4 9 9 9 9 FNIP Repeat LRR_5 PF13306.1 EGC33523.1 - 9e-07 28.6 16.7 0.0021 17.7 4.4 3.5 2 1 0 3 3 3 3 Leucine rich repeats (6 copies) DUF1389 PF07146.6 EGC33523.1 - 0.78 8.7 7.6 0.34 9.9 0.8 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF1389) Ank_2 PF12796.2 EGC33524.1 - 0.057 13.7 0.1 42 4.5 0.0 3.3 3 0 0 3 3 3 0 Ankyrin repeats (3 copies) Scramblase PF03803.10 EGC33525.1 - 4.4e-22 78.2 2.7 5.5e-22 77.9 1.8 1.1 1 0 0 1 1 1 1 Scramblase Copine PF07002.11 EGC33526.1 - 3.8e-46 156.4 0.1 6.1e-46 155.7 0.1 1.3 1 0 0 1 1 1 1 Copine C2 PF00168.25 EGC33526.1 - 5.4e-21 74.2 0.0 2.8e-12 46.2 0.0 2.3 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC33526.1 - 7.6e-09 35.6 0.0 1.4e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EGC33526.1 - 3.6e-05 23.9 0.1 6e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGC33526.1 - 6.3e-05 22.7 0.1 0.00011 22.0 0.1 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain HTH_34 PF13601.1 EGC33527.1 - 0.064 13.2 0.1 0.07 13.1 0.1 1.1 1 0 0 1 1 1 0 Winged helix DNA-binding domain TIG PF01833.19 EGC33528.1 - 1.8e-05 24.6 2.2 8.5e-05 22.4 1.5 2.2 1 0 0 1 1 1 1 IPT/TIG domain EGF_2 PF07974.8 EGC33528.1 - 0.00059 19.9 41.7 0.0026 17.9 9.4 3.0 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.5 EGC33528.1 - 0.0022 17.2 5.0 0.0047 16.2 3.4 1.5 1 0 0 1 1 1 1 Transmembrane alpha-helix domain RRXRR PF14239.1 EGC33528.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 RRXRR protein DUF3127 PF11325.3 EGC33529.1 - 0.11 12.4 1.8 2.1 8.4 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3127) DUF106 PF01956.11 EGC33529.1 - 0.38 10.2 7.6 2 7.9 5.3 2.0 1 1 0 1 1 1 0 Integral membrane protein DUF106 DUF3713 PF12506.3 EGC33529.1 - 0.42 10.6 14.0 0.07 13.2 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3713) LUC7 PF03194.10 EGC33529.1 - 1.9 7.9 10.6 2.5 7.5 7.3 1.1 1 0 0 1 1 1 0 LUC7 N_terminus DUF1525 PF07511.6 EGC33529.1 - 2 8.4 5.1 4.6 7.2 1.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1525) Notch PF00066.12 EGC33532.1 - 0.013 15.7 0.3 0.025 14.8 0.2 1.5 1 0 0 1 1 1 0 LNR domain Plasmod_Pvs28 PF06247.6 EGC33532.1 - 0.015 14.8 1.5 0.018 14.6 1.0 1.1 1 0 0 1 1 1 0 Plasmodium ookinete surface protein Pvs28 EGF_2 PF07974.8 EGC33532.1 - 0.036 14.2 1.3 0.067 13.3 0.9 1.4 1 0 0 1 1 1 0 EGF-like domain Aminotran_5 PF00266.14 EGC33533.1 - 1.5e-21 76.6 0.0 2.9e-19 69.0 0.0 2.5 1 1 0 1 1 1 1 Aminotransferase class-V ATP_bind_3 PF01171.15 EGC33533.1 - 5.2e-18 65.1 0.0 1.5e-17 63.7 0.0 1.8 1 0 0 1 1 1 1 PP-loop family zf-RING_2 PF13639.1 EGC33534.1 - 4.3e-08 32.8 11.4 4.3e-08 32.8 7.9 1.6 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGC33534.1 - 2.7e-06 26.9 12.8 6e-06 25.8 8.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC33534.1 - 4.3e-06 26.2 8.4 8.3e-06 25.3 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33534.1 - 0.00024 21.0 13.7 0.00024 21.0 9.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33534.1 - 0.00037 20.5 7.0 0.0011 19.0 4.9 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGC33534.1 - 0.0052 16.5 5.9 0.011 15.5 4.1 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-RING_5 PF14634.1 EGC33534.1 - 0.012 15.3 9.9 0.012 15.3 6.9 1.9 2 0 0 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC33534.1 - 0.017 14.9 12.3 0.038 13.8 8.5 1.6 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC33534.1 - 0.025 14.1 11.9 0.053 13.1 8.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC33534.1 - 0.053 13.3 2.7 0.1 12.4 1.9 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC33534.1 - 2.4 7.9 7.2 8.5 6.1 4.4 2.5 2 0 0 2 2 2 0 RING-type zinc-finger Borrelia_P83 PF05262.6 EGC33534.1 - 6.1 4.9 28.6 8.8 4.4 19.8 1.2 1 0 0 1 1 1 0 Borrelia P83/100 protein PKD_channel PF08016.7 EGC33535.1 - 6.1e-41 140.2 10.3 1.2e-40 139.3 7.1 1.5 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EGC33535.1 - 0.0048 16.1 25.1 0.0048 16.1 17.4 3.1 3 1 1 4 4 4 1 Ion transport protein Baculo_11_kDa PF06143.6 EGC33535.1 - 0.059 12.7 6.1 1.1 8.6 0.2 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family FUSC PF04632.7 EGC33535.1 - 0.15 10.5 7.8 0.23 9.8 5.4 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family Calpain_III PF01067.17 EGC33536.1 - 1.7e-46 157.4 1.4 8.4e-20 70.9 0.0 3.6 4 0 0 4 4 4 3 Calpain large subunit, domain III C2 PF00168.25 EGC33536.1 - 0.068 13.0 4.2 0.27 11.0 0.3 3.4 3 0 0 3 3 3 0 C2 domain ELL PF10390.4 EGC33537.1 - 0.38 9.9 5.0 0.44 9.7 3.5 1.0 1 0 0 1 1 1 0 RNA polymerase II elongation factor ELL RPA_C PF08784.6 EGC33537.1 - 2.9 8.3 5.6 1.8 9.0 2.6 1.6 1 1 0 1 1 1 0 Replication protein A C terminal Macoilin PF09726.4 EGC33537.1 - 4.3 5.5 7.5 4.5 5.4 5.2 1.0 1 0 0 1 1 1 0 Transmembrane protein Translin PF01997.11 EGC33538.1 - 5.8e-45 153.3 3.0 7.2e-45 153.0 2.1 1.0 1 0 0 1 1 1 1 Translin family PLU-1 PF08429.6 EGC33538.1 - 7.8e-05 21.7 1.8 0.00025 20.0 0.1 2.0 2 0 0 2 2 2 1 PLU-1-like protein DUF2730 PF10805.3 EGC33538.1 - 0.00064 19.4 0.4 0.0015 18.2 0.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2730) Lipoprotein_7 PF01540.11 EGC33538.1 - 0.0036 16.4 1.8 0.024 13.7 1.3 1.9 1 1 0 1 1 1 1 Adhesin lipoprotein DUF4279 PF14106.1 EGC33538.1 - 0.037 13.9 1.3 0.21 11.4 0.1 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF4279) Syntaxin-6_N PF09177.6 EGC33538.1 - 0.079 13.3 0.7 0.49 10.8 0.0 2.4 3 0 0 3 3 3 0 Syntaxin 6, N-terminal Lzipper-MIP1 PF14389.1 EGC33538.1 - 0.33 11.0 4.1 0.11 12.6 0.4 1.9 2 0 0 2 2 2 0 Leucine-zipper of ternary complex factor MIP1 FlxA PF14282.1 EGC33538.1 - 0.71 9.8 2.4 1.4 8.9 1.6 1.4 1 0 0 1 1 1 0 FlxA-like protein 2HCT PF03390.10 EGC33539.1 - 0.00042 18.8 0.3 0.00072 18.0 0.2 1.3 1 0 0 1 1 1 1 2-hydroxycarboxylate transporter family OATP PF03137.15 EGC33539.1 - 0.0035 15.4 0.3 0.0075 14.3 0.2 1.5 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family Peroxin-13_N PF04088.8 EGC33539.1 - 0.0069 16.3 2.4 0.79 9.6 0.2 2.7 2 1 0 2 2 2 2 Peroxin 13, N-terminal region DUF2371 PF10177.4 EGC33539.1 - 0.021 14.7 0.1 0.055 13.3 0.1 1.7 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2371) DUF4199 PF13858.1 EGC33539.1 - 0.03 14.2 0.0 0.03 14.2 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4199) DUF1943 PF09172.6 EGC33539.1 - 0.057 12.2 0.4 2.6 6.8 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) Peptidase_S49_N PF08496.5 EGC33539.1 - 0.27 11.0 3.8 0.87 9.3 2.6 1.9 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Cyto_ox_2 PF02322.10 EGC33539.1 - 0.44 9.6 8.0 0.2 10.7 3.1 1.8 2 0 0 2 2 2 0 Cytochrome oxidase subunit II BatD PF13584.1 EGC33539.1 - 0.8 8.2 6.5 0.062 11.8 0.6 1.8 2 0 0 2 2 2 0 Oxygen tolerance NPR3 PF03666.8 EGC33539.1 - 2.6 6.4 9.3 0.51 8.8 0.0 2.2 2 0 0 2 2 2 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF912 PF06024.7 EGC33539.1 - 4.3 7.4 11.3 0.16 12.0 0.2 3.1 3 1 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2304 PF10066.4 EGC33539.1 - 5.3 6.9 11.0 6 6.7 4.6 2.4 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2304) DUF1682 PF07946.9 EGC33539.1 - 8.3 5.1 13.2 14 4.4 9.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) Pkinase PF00069.20 EGC33540.1 - 2.3e-31 108.9 0.0 6.6e-31 107.3 0.0 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33540.1 - 1.5e-11 43.8 0.0 4.8e-11 42.2 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase WD40 PF00400.27 EGC33540.1 - 8.3e-11 41.3 2.1 0.012 15.4 0.2 4.4 4 1 0 4 4 4 3 WD domain, G-beta repeat Glyco_hydro_38 PF01074.17 EGC33541.1 - 5.3e-69 232.5 6.7 5.3e-69 232.5 4.7 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGC33541.1 - 8.5e-30 103.9 13.5 1.3e-29 103.3 9.4 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGC33541.1 - 3.3e-19 68.8 0.3 3.3e-19 68.8 0.2 2.5 2 0 0 2 2 2 1 Alpha mannosidase, middle domain RabGAP-TBC PF00566.13 EGC33543.1 - 4.1e-42 144.0 11.0 1.1e-41 142.6 1.8 2.9 2 1 0 2 2 2 1 Rab-GTPase-TBC domain BK_channel_a PF03493.13 EGC33544.1 - 1.6e-25 88.9 0.5 4.7e-24 84.2 0.0 2.9 2 0 0 2 2 2 1 Calcium-activated BK potassium channel alpha subunit Ion_trans_2 PF07885.11 EGC33544.1 - 1.3e-15 56.8 3.6 3.9e-15 55.3 2.5 1.8 1 0 0 1 1 1 1 Ion channel TrkA_N PF02254.13 EGC33544.1 - 1.5e-08 34.6 0.0 0.00046 20.1 0.0 2.7 2 0 0 2 2 2 2 TrkA-N domain Ion_trans PF00520.26 EGC33544.1 - 5.1e-08 32.4 13.7 1.2e-05 24.6 9.5 3.1 1 1 0 1 1 1 1 Ion transport protein DUF3643 PF12356.3 EGC33544.1 - 0.012 14.9 0.8 0.037 13.3 0.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3643) Lig_chan PF00060.21 EGC33544.1 - 0.035 13.8 2.0 0.049 13.3 0.3 2.0 2 0 0 2 2 2 0 Ligand-gated ion channel Complex1_LYR PF05347.10 EGC33545.1 - 2.1e-11 43.4 0.4 3.1e-11 42.9 0.3 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC33545.1 - 2.6e-10 40.3 0.3 3.9e-10 39.7 0.2 1.3 1 0 0 1 1 1 1 Complex1_LYR-like DUF3685 PF12452.3 EGC33545.1 - 0.037 13.1 1.5 0.039 13.1 1.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) OS-D PF03392.8 EGC33545.1 - 0.33 10.9 2.9 0.59 10.1 2.0 1.6 1 1 0 1 1 1 0 Insect pheromone-binding family, A10/OS-D ABC_membrane PF00664.18 EGC33546.1 - 4.1e-112 374.0 24.4 1.4e-58 198.5 3.8 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC33546.1 - 1.3e-70 236.0 0.1 1.6e-34 119.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC33546.1 - 1.4e-14 53.9 0.0 1.3e-06 27.8 0.0 3.2 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC33546.1 - 2.4e-08 34.3 6.7 0.0026 17.7 0.2 5.2 5 1 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EGC33546.1 - 2.6e-06 26.8 1.6 0.023 14.2 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGC33546.1 - 4.8e-06 26.4 1.8 0.12 12.2 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit ABC_ATPase PF09818.4 EGC33546.1 - 7.1e-06 24.8 0.4 0.026 13.1 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGC33546.1 - 2.5e-05 23.5 0.0 0.15 11.2 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGC33546.1 - 0.00043 20.3 0.3 0.26 11.2 0.0 2.6 2 1 0 2 2 2 2 AAA ATPase domain AAA_22 PF13401.1 EGC33546.1 - 0.00057 20.0 0.5 1.1 9.4 0.0 3.2 2 2 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGC33546.1 - 0.011 16.5 0.4 2.8 8.7 0.0 3.2 4 0 0 4 4 2 0 AAA domain AAA_30 PF13604.1 EGC33546.1 - 0.024 14.2 1.1 15 5.1 0.0 3.8 3 2 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGC33546.1 - 0.05 13.9 0.1 11 6.3 0.0 2.6 2 0 0 2 2 2 0 AAA domain AAA_5 PF07728.9 EGC33546.1 - 0.18 11.5 1.0 33 4.1 0.0 3.9 4 0 0 4 4 4 0 AAA domain (dynein-related subfamily) Cation_efflux PF01545.16 EGC33547.1 - 1.5e-44 152.1 5.0 1.9e-44 151.8 3.5 1.0 1 0 0 1 1 1 1 Cation efflux family EpsG PF14897.1 EGC33547.1 - 0.27 10.1 10.1 0.33 9.8 5.5 1.9 1 1 1 2 2 2 0 EpsG family DEAD PF00270.24 EGC33549.1 - 2.2e-44 150.9 0.1 5.5e-44 149.6 0.0 1.7 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC33549.1 - 6.1e-25 86.8 0.0 1.5e-24 85.6 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Beta-Casp PF10996.3 EGC33550.1 - 6.8e-21 74.5 0.1 6.6e-20 71.3 0.0 2.5 2 0 0 2 2 2 1 Beta-Casp domain CPSF100_C PF13299.1 EGC33550.1 - 4e-19 69.3 11.1 5.6e-16 59.1 0.1 3.9 3 1 1 4 4 4 2 Cleavage and polyadenylation factor 2 C-terminal RMMBL PF07521.7 EGC33550.1 - 1.7e-06 27.7 0.0 1.3e-05 24.9 0.0 2.4 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EGC33550.1 - 6.2e-06 25.9 0.0 1.1e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC33550.1 - 2.3e-05 24.0 0.0 5.7e-05 22.7 0.0 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain GTP_EFTU PF00009.22 EGC33551.1 - 3.4e-29 101.6 0.0 1.6e-28 99.4 0.0 1.9 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain GTP_EFTU_D2 PF03144.20 EGC33551.1 - 4e-09 36.4 0.1 1e-08 35.1 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 SRPRB PF09439.5 EGC33551.1 - 0.00028 20.1 1.1 0.019 14.2 0.8 2.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU_D4 PF14578.1 EGC33551.1 - 0.00099 18.7 0.0 0.0034 17.0 0.0 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 DUF663 PF04950.7 EGC33551.1 - 0.049 12.5 6.1 0.012 14.6 1.3 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF663) PduV-EutP PF10662.4 EGC33551.1 - 0.12 11.8 3.6 5.3 6.5 0.0 2.8 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation PIN_4 PF13638.1 EGC33552.1 - 0.0029 17.7 1.5 0.004 17.2 0.4 1.5 2 0 0 2 2 2 1 PIN domain TNFR_c6 PF00020.13 EGC33553.1 - 0.01 15.9 1.4 0.026 14.6 1.0 1.7 1 0 0 1 1 1 0 TNFR/NGFR cysteine-rich region TIG PF01833.19 EGC33554.1 - 3.3e-14 52.6 1.7 3.3e-14 52.6 1.2 2.1 2 0 0 2 2 2 1 IPT/TIG domain Tup_N PF08581.5 EGC33555.1 - 0.002 18.2 7.2 0.002 18.2 5.0 6.7 4 3 1 5 5 5 1 Tup N-terminal Reo_sigmaC PF04582.7 EGC33555.1 - 1.4 8.0 23.1 1.2 8.2 0.7 3.3 2 1 1 3 3 3 0 Reovirus sigma C capsid protein DUF972 PF06156.8 EGC33555.1 - 8.1 6.8 63.2 0.27 11.6 7.4 5.4 2 1 2 4 4 4 0 Protein of unknown function (DUF972) FNIP PF05725.7 EGC33556.1 - 5.8e-159 515.9 45.1 5.6e-16 58.2 0.2 13.3 6 2 6 15 15 15 15 FNIP Repeat Phage_min_tail PF05939.8 EGC33556.1 - 5e-10 39.3 0.2 18 5.3 0.0 10.2 5 4 5 11 11 11 3 Phage minor tail protein OAS1_C PF10421.4 EGC33557.1 - 5.6e-05 22.7 0.0 7e-05 22.4 0.0 1.2 1 0 0 1 1 1 1 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus Zip PF02535.17 EGC33558.1 - 6.1 5.7 10.5 0.33 9.9 2.7 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter E1-E2_ATPase PF00122.15 EGC33560.1 - 3.6e-24 85.0 0.0 1.1e-23 83.5 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC33560.1 - 1.6e-14 54.8 0.0 2.1e-13 51.1 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC33560.1 - 4.3e-11 43.3 2.6 1.4e-10 41.6 1.8 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC33560.1 - 6.4e-10 38.8 0.1 7.6e-09 35.4 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGC33560.1 - 0.0002 21.0 0.3 0.0002 21.0 0.2 2.7 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase F-box PF00646.28 EGC33561.1 - 0.0012 18.3 1.6 0.031 13.9 1.0 2.7 2 0 0 2 2 2 1 F-box domain F-box-like PF12937.2 EGC33561.1 - 0.074 12.7 0.4 0.2 11.4 0.3 1.7 1 0 0 1 1 1 0 F-box-like Bro-N PF02498.12 EGC33561.1 - 3.6 7.9 9.9 0.48 10.7 0.7 2.9 2 0 0 2 2 2 0 BRO family, N-terminal domain EGF_2 PF07974.8 EGC33563.1 - 0.19 11.9 10.0 0.49 10.6 6.9 1.7 1 0 0 1 1 1 0 EGF-like domain DUF3164 PF11363.3 EGC33564.1 - 0.0071 15.7 0.6 0.013 14.8 0.3 1.5 1 1 1 2 2 2 1 Protein of unknown function (DUF3164) RGS PF00615.14 EGC33564.1 - 0.053 13.6 2.6 0.085 12.9 1.8 1.5 1 1 0 1 1 1 0 Regulator of G protein signaling domain DUF3685 PF12452.3 EGC33564.1 - 0.074 12.2 3.0 0.094 11.8 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3685) DUF885 PF05960.6 EGC33564.1 - 0.18 10.9 2.6 0.21 10.6 1.8 1.0 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF885) C2 PF00168.25 EGC33565.1 - 6.5e-12 45.1 0.1 1.5e-11 43.9 0.0 1.7 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 EGC33565.1 - 1e-06 28.5 0.9 2.3e-05 24.2 0.1 3.3 2 1 0 2 2 2 1 Munc13 (mammalian uncoordinated) homology domain RBFA PF02033.13 EGC33566.1 - 8.7e-05 22.5 2.5 0.0097 15.9 0.4 3.1 2 0 0 2 2 2 2 Ribosome-binding factor A VWA_2 PF13519.1 EGC33567.1 - 9.4e-08 32.3 0.0 2.2e-07 31.1 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain Mem_trans PF03547.13 EGC33567.1 - 0.003 15.9 3.9 27 2.9 0.0 2.2 1 1 1 2 2 2 1 Membrane transport protein Asp-B-Hydro_N PF05279.6 EGC33567.1 - 8 6.2 22.9 12 5.6 15.9 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Profilin PF00235.14 EGC33568.1 - 2.5e-14 53.4 0.0 2.8e-14 53.2 0.0 1.0 1 0 0 1 1 1 1 Profilin E2F_TDP PF02319.15 EGC33569.1 - 2.9e-19 68.3 0.1 7.4e-19 67.0 0.0 1.7 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain TrmB PF01978.14 EGC33569.1 - 0.019 14.6 0.0 0.041 13.5 0.0 1.5 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Ribosomal_60s PF00428.14 EGC33569.1 - 0.061 13.7 1.2 0.18 12.2 0.3 2.1 2 0 0 2 2 2 0 60s Acidic ribosomal protein ADK PF00406.17 EGC33570.1 - 1.2e-61 207.0 0.0 1.5e-61 206.7 0.0 1.1 1 0 0 1 1 1 1 Adenylate kinase ADK_lid PF05191.9 EGC33570.1 - 1.1e-12 47.3 0.0 2.4e-12 46.2 0.0 1.6 1 0 0 1 1 1 1 Adenylate kinase, active site lid AAA_17 PF13207.1 EGC33570.1 - 0.00028 21.7 0.0 0.00052 20.8 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC33570.1 - 0.00074 19.4 0.0 0.0012 18.7 0.0 1.4 1 1 0 1 1 1 1 AAA domain RuvB_N PF05496.7 EGC33570.1 - 0.011 14.7 0.0 0.026 13.5 0.0 1.6 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGC33570.1 - 0.032 14.5 0.1 0.1 12.8 0.0 1.9 2 1 0 2 2 2 0 AAA domain Thymidylate_kin PF02223.12 EGC33570.1 - 0.11 11.8 0.0 5.5 6.3 0.0 2.4 2 1 0 2 2 2 0 Thymidylate kinase Torsin PF06309.6 EGC33570.1 - 0.13 12.1 0.0 15 5.4 0.0 3.0 3 0 0 3 3 3 0 Torsin TMA7 PF09072.5 EGC33571.1 - 8.8e-27 93.3 17.6 1e-26 93.1 12.2 1.0 1 0 0 1 1 1 1 Translation machinery associated TMA7 rRNA_processing PF08524.6 EGC33572.1 - 6 6.6 67.6 0.25 11.1 34.3 3.6 1 1 1 2 2 2 0 rRNA processing SNF2_N PF00176.18 EGC33573.1 - 3.5e-77 259.1 5.5 3.5e-77 259.1 3.8 1.8 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EGC33573.1 - 4.9e-18 64.5 13.6 2.6e-10 39.8 0.4 4.0 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain DUF4208 PF13907.1 EGC33573.1 - 2.7e-17 62.8 1.5 2.7e-17 62.8 1.0 4.2 3 0 0 3 3 3 1 Domain of unknown function (DUF4208) Helicase_C PF00271.26 EGC33573.1 - 1.1e-15 57.2 0.0 1.4e-14 53.6 0.0 2.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 EGC33573.1 - 0.02 14.9 0.0 0.068 13.2 0.0 2.0 1 0 0 1 1 1 0 Myb-like DNA-binding domain MutS_V PF00488.16 EGC33574.1 - 2.2e-54 184.3 0.1 4.2e-54 183.4 0.1 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC33574.1 - 2.6e-31 109.0 0.2 6.2e-31 107.7 0.0 1.7 2 0 0 2 2 2 1 MutS domain III MutS_IV PF05190.13 EGC33574.1 - 0.00086 19.4 0.0 0.00086 19.4 0.0 2.5 3 0 0 3 3 3 1 MutS family domain IV AAA_14 PF13173.1 EGC33574.1 - 0.027 14.3 0.0 0.027 14.3 0.0 4.5 6 0 0 6 6 6 0 AAA domain AAA_22 PF13401.1 EGC33574.1 - 0.094 12.8 0.1 2.1 8.4 0.0 3.0 3 0 0 3 3 3 0 AAA domain Sec8_exocyst PF04048.9 EGC33575.1 - 3.4e-17 62.4 0.5 3.4e-17 62.4 0.3 2.8 3 0 0 3 3 3 1 Sec8 exocyst complex component specific domain AMP-binding PF00501.23 EGC33576.1 - 2.7e-87 292.8 0.0 3.3e-87 292.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC33576.1 - 2.3e-11 44.4 0.0 6.3e-11 43.0 0.0 1.8 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Band_7 PF01145.20 EGC33577.1 - 6.7e-29 101.0 0.2 1.5e-28 99.9 0.1 1.6 1 0 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGC33577.1 - 0.023 14.2 0.2 0.043 13.3 0.1 1.5 1 1 0 1 1 1 0 SPFH domain-Band 7 family OSCP PF00213.13 EGC33577.1 - 0.18 11.6 3.8 0.69 9.7 1.4 2.3 1 1 1 2 2 2 0 ATP synthase delta (OSCP) subunit Adeno_E3_CR2 PF02439.10 EGC33577.1 - 2 8.0 5.3 3.8 7.1 3.7 1.3 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 Peptidase_C13 PF01650.13 EGC33578.1 - 2.2e-47 161.5 0.0 3.3e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase C13 family DUF2973 PF11189.3 EGC33578.1 - 0.074 12.8 0.0 7.4 6.4 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2973) Tctex-1 PF03645.8 EGC33579.1 - 1.4e-33 114.8 2.8 1.5e-33 114.6 2.0 1.0 1 0 0 1 1 1 1 Tctex-1 family DUF1968 PF09291.5 EGC33579.1 - 0.086 12.6 2.2 0.11 12.2 1.5 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF1968) CholecysA-Rec_N PF09193.5 EGC33579.1 - 0.13 12.1 0.2 0.25 11.2 0.2 1.5 1 0 0 1 1 1 0 Cholecystokinin A receptor, N-terminal CTD_bind PF04818.8 EGC33580.1 - 1.1e-08 35.1 0.7 1.1e-08 35.1 0.5 2.2 2 1 0 2 2 2 1 RNA polymerase II-binding domain. Rhabdo_glycop PF00974.13 EGC33580.1 - 0.13 10.5 3.3 0.17 10.0 2.3 1.1 1 0 0 1 1 1 0 Rhabdovirus spike glycoprotein Neur_chan_memb PF02932.11 EGC33580.1 - 0.69 9.7 3.0 0.95 9.2 2.1 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region FHA PF00498.21 EGC33581.1 - 1.2e-12 47.7 13.8 4.2e-12 46.0 9.6 2.0 1 1 0 1 1 1 1 FHA domain DUF2457 PF10446.4 EGC33581.1 - 0.0036 16.0 9.1 0.035 12.8 0.9 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF2457) Gti1_Pac2 PF09729.4 EGC33581.1 - 0.43 10.4 11.1 0.18 11.6 3.8 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family POX PF07526.6 EGC33581.1 - 0.61 10.3 7.9 2.1 8.5 2.4 2.3 2 0 0 2 2 2 0 Associated with HOX DUF4611 PF15387.1 EGC33581.1 - 4.1 7.6 12.0 8.4 6.6 1.8 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF2076 PF09849.4 EGC33581.1 - 7.8 6.4 22.5 3 7.8 4.7 2.1 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2076) ERCC4 PF02732.10 EGC33583.1 - 8.9e-05 22.2 0.9 0.00031 20.5 0.7 2.0 1 0 0 1 1 1 1 ERCC4 domain Peptidase_C1 PF00112.18 EGC33584.1 - 7.3e-85 284.2 3.8 1e-84 283.7 2.6 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC33584.1 - 3.4e-14 52.8 1.6 5.8e-14 52.1 1.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC33584.1 - 0.0053 15.3 1.7 0.018 13.6 0.3 2.1 2 0 0 2 2 2 1 Peptidase C1-like family YvbH_ext PF11724.3 EGC33584.1 - 0.17 11.6 1.7 0.4 10.3 1.2 1.7 1 0 0 1 1 1 0 YvbH-like oligomerisation region Peptidase_C1 PF00112.18 EGC33585.1 - 5.1e-84 281.5 6.3 7.1e-84 281.0 4.4 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC33585.1 - 1.5e-13 50.7 2.2 2.4e-13 50.1 1.5 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC33585.1 - 0.0017 16.9 1.2 0.0053 15.3 0.2 2.0 2 0 0 2 2 2 1 Peptidase C1-like family DUF912 PF06024.7 EGC33586.1 - 0.0018 18.2 0.2 0.0066 16.4 0.1 1.9 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4448 PF14610.1 EGC33586.1 - 0.002 17.6 3.7 0.0028 17.1 0.0 2.8 3 0 0 3 3 3 1 Protein of unknown function (DUF4448) VSP PF03302.8 EGC33586.1 - 0.0022 16.7 0.1 0.0034 16.0 0.1 1.2 1 0 0 1 1 1 1 Giardia variant-specific surface protein Mid2 PF04478.7 EGC33586.1 - 0.0052 16.2 0.3 0.0052 16.2 0.2 1.9 2 0 0 2 2 2 1 Mid2 like cell wall stress sensor Podoplanin PF05808.6 EGC33586.1 - 0.017 14.7 0.2 0.03 13.8 0.1 1.3 1 0 0 1 1 1 0 Podoplanin DUF4006 PF13179.1 EGC33586.1 - 0.084 12.4 3.7 0.11 12.0 0.0 3.0 3 0 0 3 3 3 0 Family of unknown function (DUF4006) Beta_elim_lyase PF01212.16 EGC33587.1 - 9e-85 284.3 0.0 1.1e-84 284.0 0.0 1.0 1 0 0 1 1 1 1 Beta-eliminating lyase E1-E2_ATPase PF00122.15 EGC33588.1 - 2.8e-56 190.1 1.0 6.9e-55 185.5 0.1 3.1 3 0 0 3 3 3 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC33588.1 - 7.2e-38 129.9 9.9 7.2e-38 129.9 6.8 3.1 3 1 1 4 4 4 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC33588.1 - 3.7e-22 79.8 0.0 1.3e-21 78.0 0.0 1.9 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC33588.1 - 4.7e-12 45.1 0.0 1.1e-11 43.9 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGC33588.1 - 7.2e-10 38.6 0.0 9.5e-09 35.1 0.0 2.4 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGC33588.1 - 2.7e-09 37.4 0.0 1.1e-08 35.4 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGC33588.1 - 1e-07 31.7 2.5 4.3e-05 23.2 0.7 2.7 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Actin PF00022.14 EGC33589.1 - 8.9e-131 435.9 0.0 1.2e-130 435.4 0.0 1.2 1 0 0 1 1 1 1 Actin Ist1 PF03398.9 EGC33589.1 - 3.7e-51 172.8 0.4 5.4e-51 172.2 0.3 1.2 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Filamin PF00630.14 EGC33589.1 - 1.3e-31 109.1 1.1 7.7e-15 55.2 0.0 2.7 3 0 0 3 3 3 2 Filamin/ABP280 repeat Big_1 PF02369.11 EGC33589.1 - 0.0013 18.6 0.5 0.25 11.2 0.2 2.6 2 0 0 2 2 2 1 Bacterial Ig-like domain (group 1) DUF3989 PF13150.1 EGC33589.1 - 0.086 12.3 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3989) Y_Y_Y PF07495.8 EGC33589.1 - 0.12 12.1 2.3 5.7 6.7 0.2 3.2 3 0 0 3 3 3 0 Y_Y_Y domain Big_3_4 PF13754.1 EGC33589.1 - 0.16 12.3 3.6 2.4 8.5 0.5 3.0 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 3) NOT2_3_5 PF04153.13 EGC33590.1 - 5.5e-33 113.7 3.7 5.5e-33 113.7 2.5 3.8 3 1 0 4 4 4 1 NOT2 / NOT3 / NOT5 family ABC_membrane PF00664.18 EGC33591.1 - 4.8e-116 386.9 20.4 9.6e-59 199.0 4.4 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC33591.1 - 1.3e-68 229.5 0.1 5.5e-35 120.6 0.0 2.6 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC33591.1 - 2.8e-16 59.4 0.0 1.3e-06 27.8 0.0 3.8 2 2 1 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC33591.1 - 4.5e-09 36.6 23.4 0.014 15.3 0.1 5.9 4 2 1 5 5 5 3 AAA domain ABC_ATPase PF09818.4 EGC33591.1 - 1.4e-06 27.2 1.7 0.0062 15.1 0.0 2.7 3 0 0 3 3 3 2 Predicted ATPase of the ABC class DUF258 PF03193.11 EGC33591.1 - 1.9e-06 27.1 0.0 0.063 12.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC33591.1 - 1.4e-05 24.4 2.1 0.11 12.0 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGC33591.1 - 2.3e-05 24.2 6.0 0.003 17.4 0.3 3.7 3 2 0 3 3 3 2 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EGC33591.1 - 0.00015 21.8 0.0 0.098 12.6 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EGC33591.1 - 0.00051 19.7 0.3 8.4 6.1 0.0 4.3 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) APS_kinase PF01583.15 EGC33591.1 - 0.0033 17.1 0.0 0.5 10.0 0.0 2.5 2 0 0 2 2 2 1 Adenylylsulphate kinase AAA_17 PF13207.1 EGC33591.1 - 0.012 16.4 0.1 3 8.6 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGC33591.1 - 0.09 13.0 5.1 1.7 8.9 0.0 3.4 3 0 0 3 3 2 0 AAA domain AAA_25 PF13481.1 EGC33591.1 - 0.14 11.5 1.5 11 5.3 0.2 3.1 3 1 0 3 3 3 0 AAA domain DUF2391 PF09622.5 EGC33593.1 - 0.14 11.3 0.0 0.29 10.2 0.0 1.5 2 0 0 2 2 2 0 Putative integral membrane protein (DUF2391) DUF1689 PF07954.6 EGC33594.1 - 0.017 15.0 0.0 0.047 13.5 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1689) DUF4064 PF13273.1 EGC33594.1 - 0.024 14.7 6.0 0.26 11.4 0.3 2.9 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) Epimerase PF01370.16 EGC33595.1 - 7.4e-21 74.6 0.0 1.3e-19 70.6 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC33595.1 - 3e-16 58.9 0.1 3.5e-08 32.4 0.0 3.1 2 1 0 2 2 2 2 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGC33595.1 - 5.4e-14 51.7 0.1 6.4e-10 38.3 0.0 2.6 2 1 0 2 2 2 2 Male sterility protein RmlD_sub_bind PF04321.12 EGC33595.1 - 2.7e-08 33.0 0.0 0.032 13.1 0.0 3.1 3 0 0 3 3 3 3 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC33595.1 - 2.3e-06 26.7 0.0 0.005 15.7 0.0 3.0 2 1 1 3 3 3 2 Polysaccharide biosynthesis protein Adeno_GP19K PF04881.8 EGC33595.1 - 0.093 12.4 0.0 0.22 11.2 0.0 1.6 1 1 0 1 1 1 0 Adenovirus GP19K Bmp PF02608.9 EGC33596.1 - 0.0086 14.8 0.2 0.0091 14.7 0.1 1.1 1 0 0 1 1 1 1 Basic membrane protein Leukemia_assc_2 PF15197.1 EGC33596.1 - 0.19 11.4 2.0 0.23 11.1 0.1 2.0 2 0 0 2 2 2 0 Leukemia-associated protein 2 AMP-binding PF00501.23 EGC33597.1 - 2.1e-63 214.1 0.0 2.5e-63 213.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme V_ATPase_I PF01496.14 EGC33598.1 - 2.1e-281 935.2 3.5 2.4e-281 935.0 2.4 1.0 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family FTA4 PF13093.1 EGC33598.1 - 0.00056 19.4 3.8 0.0011 18.4 2.6 1.5 1 0 0 1 1 1 1 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 HSBP1 PF06825.7 EGC33598.1 - 0.15 11.6 2.5 5.9 6.5 0.1 2.8 3 0 0 3 3 3 0 Heat shock factor binding protein 1 Nop25 PF09805.4 EGC33599.1 - 0.091 12.8 4.2 0.13 12.3 2.9 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF4612 PF15389.1 EGC33599.1 - 0.51 10.9 7.9 0.31 11.6 4.1 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4612) BPL_N PF09825.4 EGC33599.1 - 0.66 8.6 5.1 0.83 8.3 3.5 1.0 1 0 0 1 1 1 0 Biotin-protein ligase, N terminal DUF3236 PF11576.3 EGC33599.1 - 2.9 7.3 5.4 7 6.0 2.5 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3236) Mem_trans PF03547.13 EGC33599.1 - 3.4 5.8 7.9 5.5 5.1 5.5 1.6 1 1 0 1 1 1 0 Membrane transport protein EMP70 PF02990.11 EGC33599.1 - 5.6 5.3 12.2 0.14 10.5 3.4 1.7 1 1 1 2 2 2 0 Endomembrane protein 70 Sex_peptide PF08138.6 EGC33601.1 - 0.02 14.6 0.0 0.027 14.3 0.0 1.2 1 0 0 1 1 1 0 Sex peptide (SP) family ENTH PF01417.15 EGC33602.1 - 6.5e-44 148.7 0.0 1e-43 148.1 0.0 1.3 1 0 0 1 1 1 1 ENTH domain ANTH PF07651.11 EGC33602.1 - 0.0087 14.7 0.0 0.017 13.8 0.0 1.4 1 0 0 1 1 1 1 ANTH domain F-box-like PF12937.2 EGC33603.1 - 1.1e-12 47.4 0.3 2.1e-12 46.5 0.2 1.4 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC33603.1 - 7.3e-11 41.4 0.1 1.5e-10 40.4 0.1 1.5 1 0 0 1 1 1 1 F-box domain Elongin_A PF06881.6 EGC33603.1 - 0.14 12.5 3.8 1.5 9.2 0.0 3.2 3 0 0 3 3 3 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF912 PF06024.7 EGC33606.1 - 0.12 12.4 0.2 0.12 12.4 0.2 2.4 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EGF_2 PF07974.8 EGC33606.1 - 0.17 12.0 8.1 0.59 10.3 5.6 1.9 1 1 0 1 1 1 0 EGF-like domain BAF1_ABF1 PF04684.8 EGC33607.1 - 0.00036 19.5 10.7 0.00038 19.4 7.4 1.1 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor FimP PF09766.4 EGC33607.1 - 0.0017 17.4 13.6 0.0019 17.3 9.5 1.2 1 0 0 1 1 1 1 Fms-interacting protein OATP PF03137.15 EGC33607.1 - 0.0048 15.0 2.1 0.0051 14.9 1.5 1.2 1 0 0 1 1 1 1 Organic Anion Transporter Polypeptide (OATP) family CDK5_activator PF03261.10 EGC33607.1 - 0.0099 15.2 10.9 0.012 15.0 7.6 1.1 1 0 0 1 1 1 1 Cyclin-dependent kinase 5 activator protein FemAB PF02388.11 EGC33607.1 - 0.01 14.5 8.5 0.012 14.2 5.9 1.1 1 0 0 1 1 1 0 FemAB family Mem_trans PF03547.13 EGC33607.1 - 0.015 13.6 3.0 0.016 13.4 2.1 1.1 1 0 0 1 1 1 0 Membrane transport protein Serinc PF03348.10 EGC33607.1 - 0.04 12.6 2.7 0.041 12.6 1.9 1.2 1 0 0 1 1 1 0 Serine incorporator (Serinc) Nucleoside_tran PF01733.13 EGC33607.1 - 0.046 12.8 3.1 0.06 12.5 2.1 1.1 1 0 0 1 1 1 0 Nucleoside transporter Pox_Ag35 PF03286.9 EGC33607.1 - 0.055 13.0 8.7 0.069 12.6 6.0 1.1 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Kei1 PF08552.6 EGC33607.1 - 0.075 12.6 1.1 0.089 12.4 0.8 1.2 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 Tim54 PF11711.3 EGC33607.1 - 0.08 11.5 4.9 0.088 11.3 3.4 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 TT_ORF1 PF02956.9 EGC33607.1 - 0.094 11.1 11.6 0.1 11.0 8.0 1.1 1 0 0 1 1 1 0 TT viral orf 1 Ctr PF04145.10 EGC33607.1 - 0.1 12.6 1.1 0.13 12.3 0.8 1.3 1 0 0 1 1 1 0 Ctr copper transporter family Peptidase_S64 PF08192.6 EGC33607.1 - 0.1 10.8 10.4 0.12 10.6 7.2 1.0 1 0 0 1 1 1 0 Peptidase family S64 AIF_C PF14721.1 EGC33607.1 - 0.15 12.3 6.5 0.21 11.8 4.5 1.2 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Hid1 PF12722.2 EGC33607.1 - 0.18 9.4 14.8 0.2 9.3 10.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Zip PF02535.17 EGC33607.1 - 0.24 10.3 0.6 0.28 10.1 0.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Band_3_cyto PF07565.8 EGC33607.1 - 0.27 10.7 5.8 0.34 10.3 4.0 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Pex16 PF08610.5 EGC33607.1 - 0.4 9.6 6.0 0.47 9.3 4.1 1.1 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) DUF4175 PF13779.1 EGC33607.1 - 0.63 7.6 20.7 3.8 5.0 15.1 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4175) FAM176 PF14851.1 EGC33607.1 - 0.75 9.4 6.5 1.1 8.9 4.5 1.3 1 0 0 1 1 1 0 FAM176 family DUF3464 PF11947.3 EGC33607.1 - 1.2 8.6 11.0 1.7 8.1 7.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3464) Gti1_Pac2 PF09729.4 EGC33607.1 - 1.2 8.9 9.7 1.5 8.6 6.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Paramyxo_ncap PF00973.14 EGC33607.1 - 1.2 7.7 6.0 1.4 7.5 4.2 1.2 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Pex14_N PF04695.8 EGC33607.1 - 1.3 9.0 12.1 1.9 8.5 8.4 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 EGC33607.1 - 1.7 7.0 7.7 1.9 6.8 5.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PBP1_TM PF14812.1 EGC33607.1 - 4 7.8 8.3 7.1 7.0 5.7 1.4 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Pro_isomerase PF00160.16 EGC33608.1 - 2.1e-47 161.2 0.0 2.4e-47 161.0 0.0 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Actin PF00022.14 EGC33609.1 - 1.5e-54 184.9 0.0 6.2e-52 176.3 0.0 2.3 1 1 0 1 1 1 1 Actin CLASP_N PF12348.3 EGC33610.1 - 5.9e-46 156.6 3.1 6.7e-46 156.4 2.1 1.0 1 0 0 1 1 1 1 CLASP N terminal DUF4441 PF14536.1 EGC33610.1 - 0.011 15.7 2.8 0.18 11.7 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4441) FNIP PF05725.7 EGC33611.1 - 7.2e-118 384.3 39.7 2.9e-15 55.9 0.1 9.1 7 1 1 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.8 EGC33611.1 - 1e-05 25.4 1.4 14 5.6 0.0 7.2 3 3 7 10 10 10 1 Phage minor tail protein DUF1769 PF08588.5 EGC33611.1 - 0.0003 20.6 31.1 3.7 7.5 0.1 10.7 3 3 10 13 13 13 4 Protein of unknown function (DUF1769) LRR_8 PF13855.1 EGC33611.1 - 0.0012 18.5 3.0 3.4 7.4 0.1 5.4 3 2 0 5 5 5 1 Leucine rich repeat Keratin_matx PF04579.7 EGC33611.1 - 0.02 15.1 1.3 9.2 6.6 0.1 3.8 2 1 2 4 4 4 0 Keratin, high-sulphur matrix protein Merozoite_SPAM PF07133.6 EGC33612.1 - 0.0019 18.1 36.8 0.0019 18.1 25.5 3.8 4 0 0 4 4 4 1 Merozoite surface protein (SPAM) BTB PF00651.26 EGC33612.1 - 0.0036 17.2 1.3 0.037 14.0 0.1 3.2 3 0 0 3 3 3 1 BTB/POZ domain DUF2052 PF09747.4 EGC33612.1 - 9.9 6.0 51.8 2.9 7.7 17.9 3.6 3 0 0 3 3 3 0 Coiled-coil domain containing protein (DUF2052) Rap_GAP PF02145.10 EGC33613.1 - 5.3e-60 202.0 0.1 5.3e-60 202.0 0.1 2.2 3 0 0 3 3 3 1 Rap/ran-GAP CNH PF00780.17 EGC33613.1 - 9.1e-36 123.6 0.3 1.2e-34 119.9 0.2 2.2 1 1 0 1 1 1 1 CNH domain Pex14_N PF04695.8 EGC33613.1 - 0.018 15.1 1.4 0.018 15.1 1.0 3.0 2 1 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region NAC PF01849.13 EGC33613.1 - 0.15 11.5 1.4 3.2 7.3 0.1 2.7 2 0 0 2 2 2 0 NAC domain RNA_pol_Rpb5_C PF01191.14 EGC33614.1 - 1.4e-34 117.5 0.2 2.9e-34 116.4 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb5, C-terminal domain RNA_pol_Rpb5_N PF03871.9 EGC33614.1 - 4.4e-14 52.6 0.8 7.8e-13 48.6 0.1 2.7 2 1 0 2 2 2 1 RNA polymerase Rpb5, N-terminal domain Pox_A32 PF04665.7 EGC33614.1 - 0.008 15.4 1.4 0.013 14.8 0.7 1.5 1 1 0 1 1 1 1 Poxvirus A32 protein Mrr_cat PF04471.7 EGC33614.1 - 0.046 13.5 0.2 0.077 12.8 0.1 1.4 1 1 0 1 1 1 0 Restriction endonuclease POTRA_2 PF08479.6 EGC33614.1 - 0.057 13.0 0.1 0.21 11.2 0.0 1.9 2 0 0 2 2 2 0 POTRA domain, ShlB-type Phage_rep_org_N PF09681.5 EGC33614.1 - 0.091 12.3 0.4 0.17 11.4 0.3 1.4 1 0 0 1 1 1 0 N-terminal phage replisome organiser (Phage_rep_org_N) Copine PF07002.11 EGC33615.1 - 2.6e-36 124.5 0.0 4.2e-36 123.8 0.0 1.4 1 0 0 1 1 1 1 Copine C2 PF00168.25 EGC33615.1 - 1.5e-19 69.6 2.7 1.6e-09 37.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC33615.1 - 7.2e-08 32.4 0.0 1.7e-07 31.2 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA_2 PF13519.1 EGC33615.1 - 0.00088 19.4 0.0 0.0014 18.7 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain zf-RING_2 PF13639.1 EGC33617.1 - 2.7e-07 30.3 11.7 5.9e-07 29.2 8.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC33617.1 - 5.3e-07 29.2 9.7 9e-07 28.4 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC33617.1 - 2e-05 24.1 13.5 4e-05 23.1 9.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33617.1 - 7.3e-05 22.7 6.5 7.3e-05 22.7 4.5 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger THRAP3_BCLAF1 PF15440.1 EGC33617.1 - 9.2e-05 21.3 34.0 0.00014 20.7 23.6 1.3 1 0 0 1 1 1 1 THRAP3/BCLAF1 family zf-C3HC4_2 PF13923.1 EGC33617.1 - 0.0002 21.2 13.8 0.00039 20.3 9.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Macoilin PF09726.4 EGC33617.1 - 0.0011 17.3 38.7 0.0016 16.8 26.8 1.1 1 0 0 1 1 1 1 Transmembrane protein zf-RING_4 PF14570.1 EGC33617.1 - 0.02 14.4 12.0 0.039 13.5 8.3 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGC33617.1 - 0.12 12.1 13.6 0.14 11.9 8.4 1.9 1 1 1 2 2 2 0 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC33617.1 - 0.56 10.1 12.6 1.3 8.9 8.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING HA2 PF04408.18 EGC33619.1 - 1.2e-25 89.5 1.9 2.8e-25 88.2 0.0 2.3 2 0 0 2 2 2 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGC33619.1 - 9.3e-21 73.7 0.0 2.1e-20 72.6 0.0 1.7 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold DEAD PF00270.24 EGC33619.1 - 0.025 14.0 0.0 0.088 12.2 0.0 1.9 1 1 0 1 1 1 0 DEAD/DEAH box helicase Pkinase PF00069.20 EGC33620.1 - 2.6e-39 134.9 0.1 6.7e-39 133.6 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33620.1 - 9.4e-27 93.7 0.0 1.8e-26 92.8 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EGC33620.1 - 5.9e-09 35.8 9.6 1.2e-08 34.9 3.6 3.8 4 1 0 4 4 4 1 Ribonuclease 2-5A Kdo PF06293.9 EGC33620.1 - 0.038 13.0 0.0 0.087 11.8 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC33620.1 - 0.28 10.8 0.1 0.44 10.2 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Ras PF00071.17 EGC33622.1 - 6.9e-23 80.8 0.0 1e-22 80.2 0.0 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33622.1 - 1.4e-11 44.8 0.0 2.4e-11 44.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Pox_A32 PF04665.7 EGC33622.1 - 0.017 14.4 0.2 0.056 12.7 0.0 1.8 2 0 0 2 2 2 0 Poxvirus A32 protein AAA_14 PF13173.1 EGC33622.1 - 0.026 14.4 0.5 0.087 12.7 0.3 2.0 1 1 0 1 1 1 0 AAA domain Ras PF00071.17 EGC33623.1 - 9.2e-25 86.9 0.6 1.5e-24 86.2 0.4 1.3 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC33623.1 - 1.8e-09 38.1 0.0 3.9e-09 37.0 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGC33624.1 - 1e-24 86.7 0.2 1.3e-24 86.4 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33624.1 - 1.6e-07 31.8 0.0 2.9e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGC33624.1 - 0.0025 17.0 0.1 0.007 15.5 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGC33624.1 - 0.0032 16.6 0.2 0.0036 16.4 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGC33624.1 - 0.012 14.8 0.0 0.02 14.1 0.0 1.5 1 1 0 1 1 1 0 ADP-ribosylation factor family AAA_14 PF13173.1 EGC33624.1 - 0.16 11.8 3.9 0.05 13.5 0.5 1.7 2 1 0 2 2 2 0 AAA domain Pkinase PF00069.20 EGC33625.1 - 2e-58 197.5 0.0 3.8e-58 196.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33625.1 - 5.1e-45 153.5 0.0 7.6e-45 152.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SH3_9 PF14604.1 EGC33625.1 - 2.2e-08 33.5 0.0 3.9e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC33625.1 - 4e-08 32.6 0.0 8.5e-08 31.5 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC33625.1 - 4e-06 26.1 0.0 7.2e-06 25.2 0.0 1.5 1 0 0 1 1 1 1 SH3 domain Kinase-like PF14531.1 EGC33625.1 - 7e-05 21.9 0.0 0.00013 21.0 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC33625.1 - 0.0015 18.3 0.0 0.0023 17.7 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC33625.1 - 0.0092 14.8 0.0 0.019 13.7 0.0 1.4 1 0 0 1 1 1 1 Seadornavirus VP7 CBM49 PF09478.5 EGC33626.1 - 1.9e-32 111.1 9.4 4.4e-22 77.9 0.8 2.3 2 0 0 2 2 2 2 Carbohydrate binding domain CBM49 Neisseria_TspB PF05616.8 EGC33626.1 - 0.13 10.6 24.6 0.078 11.3 8.8 2.1 2 0 0 2 2 2 0 Neisseria meningitidis TspB protein PRCC PF10253.4 EGC33626.1 - 0.16 12.6 13.1 1.8 9.2 1.3 2.2 2 0 0 2 2 2 0 Mitotic checkpoint regulator, MAD2B-interacting Erf4 PF10256.4 EGC33628.1 - 5.4e-05 23.0 1.4 5.4e-05 23.0 1.0 2.1 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family POX PF07526.6 EGC33628.1 - 0.39 10.9 4.5 0.58 10.3 3.1 1.3 1 0 0 1 1 1 0 Associated with HOX Med21 PF11221.3 EGC33628.1 - 0.46 10.4 5.0 0.92 9.4 3.5 1.5 1 0 0 1 1 1 0 Subunit 21 of Mediator complex FimP PF09766.4 EGC33628.1 - 0.76 8.7 15.7 1.1 8.2 10.9 1.2 1 0 0 1 1 1 0 Fms-interacting protein NRDE-2 PF08424.5 EGC33628.1 - 1.1 8.0 12.3 1.6 7.4 8.5 1.2 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference TMEM51 PF15345.1 EGC33628.1 - 1.3 8.6 6.1 13 5.4 0.1 2.2 2 0 0 2 2 2 0 Transmembrane protein 51 Eapp_C PF10238.4 EGC33628.1 - 2.7 7.8 19.0 5.6 6.8 13.2 1.6 1 0 0 1 1 1 0 E2F-associated phosphoprotein Ctr PF04145.10 EGC33629.1 - 0.051 13.6 5.9 1.5 8.8 0.0 2.5 2 1 0 2 2 2 0 Ctr copper transporter family DUF853 PF05872.7 EGC33629.1 - 0.45 8.8 2.4 0.6 8.3 1.7 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Glyco_transf_9 PF01075.12 EGC33629.1 - 3.5 6.7 5.5 5.7 6.0 3.8 1.2 1 0 0 1 1 1 0 Glycosyltransferase family 9 (heptosyltransferase) Spt20 PF12090.3 EGC33629.1 - 8 5.7 16.5 0.21 10.9 5.9 2.1 2 0 0 2 2 2 0 Spt20 family Nucleoside_tran PF01733.13 EGC33630.1 - 2.4e-36 125.4 17.4 2.4e-36 125.4 12.1 1.8 2 0 0 2 2 2 1 Nucleoside transporter FNIP PF05725.7 EGC33632.1 - 1.3e-173 562.7 66.5 2.4e-15 56.2 0.9 14.5 9 3 3 14 14 14 14 FNIP Repeat DUF3215 PF11503.3 EGC33632.1 - 0.036 13.6 0.1 1.3 8.7 0.0 3.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) Shigella_OspC PF06128.6 EGC33632.1 - 0.31 10.4 19.9 9.3 5.6 0.1 8.1 2 2 10 13 13 13 0 Shigella flexneri OspC protein zf-RING_2 PF13639.1 EGC33633.1 - 5.2e-10 38.9 8.1 8.5e-10 38.3 5.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC33633.1 - 2.8e-08 33.3 6.5 4.7e-08 32.5 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC33633.1 - 5.9e-07 29.0 10.0 1.2e-06 28.1 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33633.1 - 8.3e-07 29.0 3.4 2.1e-06 27.7 2.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC33633.1 - 4.5e-06 26.5 9.9 8.2e-06 25.7 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33633.1 - 0.00011 21.8 8.8 0.00021 20.9 6.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Macoilin PF09726.4 EGC33633.1 - 0.0022 16.3 38.1 0.003 15.9 26.4 1.1 1 0 0 1 1 1 1 Transmembrane protein zf-RING_4 PF14570.1 EGC33633.1 - 0.0027 17.2 9.8 0.005 16.3 6.8 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC33633.1 - 0.0056 16.4 1.0 0.014 15.2 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC33633.1 - 0.024 14.5 9.5 0.067 13.0 6.6 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Baculo_IE-1 PF05290.6 EGC33633.1 - 0.027 14.2 2.6 0.037 13.7 0.6 2.0 2 0 0 2 2 2 0 Baculovirus immediate-early protein (IE-0) zf-RING_6 PF14835.1 EGC33633.1 - 0.057 13.2 3.3 0.13 12.0 2.3 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Prok-RING_4 PF14447.1 EGC33633.1 - 0.2 11.2 3.9 0.42 10.1 2.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EGC33633.1 - 0.48 10.3 5.8 1.1 9.1 4.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 EGC33633.1 - 0.8 9.4 4.2 2.3 8.0 2.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EGC33633.1 - 0.99 9.2 4.9 3.4 7.5 3.4 1.9 1 1 0 1 1 1 0 Double zinc ribbon DUF3444 PF11926.3 EGC33635.1 - 0.11 11.7 0.1 0.15 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3444) FH2 PF02181.18 EGC33637.1 - 4.3e-80 269.3 0.8 4.3e-80 269.3 0.5 3.2 3 0 0 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EGC33637.1 - 2.2e-29 102.3 3.6 2.2e-29 102.3 2.5 3.2 4 0 0 4 4 4 1 Diaphanous FH3 Domain C1_1 PF00130.17 EGC33637.1 - 0.00065 19.3 9.2 0.0013 18.3 6.4 1.4 1 0 0 1 1 1 1 Phorbol esters/diacylglycerol binding domain (C1 domain) RhoGAP PF00620.22 EGC33638.1 - 2.5e-28 98.6 0.1 1.6e-27 95.9 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain Phage_HK97_TLTM PF06120.6 EGC33638.1 - 0.0058 15.9 0.3 0.017 14.4 0.2 1.8 1 0 0 1 1 1 1 Tail length tape measure protein IncA PF04156.9 EGC33638.1 - 6.3 6.3 12.9 1.7 8.2 1.0 3.3 3 0 0 3 3 3 0 IncA protein RasGEF PF00617.14 EGC33639.1 - 1.7e-61 207.2 1.5 4e-61 206.0 1.0 1.6 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC33639.1 - 3e-22 78.7 2.3 3e-22 78.7 1.6 3.0 3 1 0 3 3 3 1 RasGEF N-terminal motif FERM_N PF09379.5 EGC33639.1 - 0.00018 21.4 1.5 1.5 8.8 0.0 4.4 3 1 0 3 3 3 2 FERM N-terminal domain UPF0075 PF03702.9 EGC33640.1 - 8.5e-138 459.1 0.2 9.8e-138 458.9 0.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0075) MtrG PF04210.8 EGC33640.1 - 0.076 12.6 0.1 0.18 11.4 0.1 1.6 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, subunit G UDPG_MGDP_dh_N PF03721.9 EGC33640.1 - 0.083 12.2 0.0 0.18 11.1 0.0 1.6 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain PA28_beta PF02252.13 EGC33641.1 - 3.7e-40 136.8 3.4 6.5e-40 136.0 2.3 1.3 1 0 0 1 1 1 1 Proteasome activator pa28 beta subunit PA28_alpha PF02251.13 EGC33641.1 - 0.005 16.9 0.7 0.021 14.9 0.1 2.2 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit ETC_C1_NDUFA5 PF04716.9 EGC33641.1 - 2 8.0 4.9 2.5 7.6 0.1 3.0 3 0 0 3 3 3 0 ETC complex I subunit conserved region SNF2_N PF00176.18 EGC33642.1 - 2.8e-64 216.7 0.1 4.5e-64 216.1 0.1 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC33642.1 - 4e-12 45.8 0.0 1.5e-11 43.9 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC33642.1 - 1.2e-07 31.3 1.1 2.5e-07 30.3 0.2 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGC33642.1 - 1.2e-05 25.2 0.3 1.2e-05 25.2 0.2 3.7 3 2 1 4 4 4 1 Type III restriction enzyme, res subunit DUF1657 PF07870.6 EGC33642.1 - 0.029 14.0 0.3 0.1 12.2 0.2 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1657) AAA_22 PF13401.1 EGC33642.1 - 0.038 14.1 0.7 0.65 10.1 0.1 2.9 2 2 1 3 3 3 0 AAA domain EGF_2 PF07974.8 EGC33643.1 - 3.8e-05 23.7 28.7 0.013 15.6 9.5 2.6 2 0 0 2 2 2 2 EGF-like domain TIG PF01833.19 EGC33643.1 - 0.00018 21.3 0.2 0.00018 21.3 0.1 6.4 5 2 2 7 7 7 1 IPT/TIG domain SHOCT PF09851.4 EGC33644.1 - 3.4e-08 32.6 0.0 5.5e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Short C-terminal domain TFIIS_C PF01096.13 EGC33646.1 - 5.1e-18 64.4 2.4 5.1e-18 64.4 1.7 2.6 2 1 1 3 3 3 1 Transcription factor S-II (TFIIS) DUF523 PF04463.7 EGC33646.1 - 5.5e-05 22.9 0.5 6.7e-05 22.6 0.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF523) zf-ribbon_3 PF13248.1 EGC33646.1 - 0.002 17.3 6.4 0.09 12.0 0.0 3.0 3 0 0 3 3 3 2 zinc-ribbon domain IBR PF01485.16 EGC33646.1 - 0.0034 17.2 8.6 0.13 12.1 1.3 2.3 2 0 0 2 2 2 2 IBR domain DZR PF12773.2 EGC33646.1 - 0.0055 16.5 1.9 0.0055 16.5 1.3 2.9 2 1 0 2 2 2 1 Double zinc ribbon Cys_rich_CPCC PF14206.1 EGC33646.1 - 0.01 15.3 1.5 0.11 12.0 0.1 2.3 2 0 0 2 2 2 0 Cysteine-rich CPCC Baculo_LEF5_C PF11792.3 EGC33646.1 - 0.05 12.9 0.7 0.05 12.9 0.5 2.4 3 0 0 3 3 3 0 Baculoviridae late expression factor 5 C-terminal domain Zn_Tnp_IS1595 PF12760.2 EGC33646.1 - 0.065 13.0 1.4 0.065 13.0 1.0 2.5 2 0 0 2 2 2 0 Transposase zinc-ribbon domain DUF2387 PF09526.5 EGC33646.1 - 0.068 13.0 7.4 2.3 8.1 0.6 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) zf-LSD1 PF06943.7 EGC33646.1 - 0.15 11.6 0.4 0.15 11.6 0.3 2.8 3 1 0 3 3 2 0 LSD1 zinc finger TF_Zn_Ribbon PF08271.7 EGC33646.1 - 0.3 10.4 0.1 0.3 10.4 0.0 3.3 3 1 0 3 3 3 0 TFIIB zinc-binding zf-C4_Topoisom PF01396.14 EGC33646.1 - 0.46 10.0 11.0 0.38 10.3 0.9 2.9 2 2 0 2 2 2 0 Topoisomerase DNA binding C4 zinc finger RNA_POL_M_15KD PF02150.11 EGC33646.1 - 0.51 10.0 10.8 0.54 10.0 1.6 3.2 2 1 0 2 2 2 0 RNA polymerases M/15 Kd subunit DNA_RNApol_7kD PF03604.8 EGC33646.1 - 0.67 9.4 7.6 12 5.4 0.1 3.7 3 1 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit PhnA_Zn_Ribbon PF08274.7 EGC33646.1 - 0.82 9.5 7.9 2.6 7.8 0.2 2.9 2 1 0 2 2 2 0 PhnA Zinc-Ribbon Ribosomal_S27e PF01667.12 EGC33646.1 - 1 8.9 9.8 0.34 10.4 1.0 3.0 2 1 0 2 2 2 0 Ribosomal protein S27 VP_N-CPKC PF11475.3 EGC33646.1 - 1.2 8.6 5.5 26 4.4 0.1 3.4 3 0 0 3 3 3 0 Virion protein N terminal domain zf-RING_3 PF14369.1 EGC33646.1 - 1.3 9.0 10.7 4.2 7.4 1.9 2.9 3 0 0 3 3 3 0 zinc-finger C1_4 PF07975.7 EGC33646.1 - 1.8 8.6 15.1 3.5 7.7 2.0 3.3 1 1 2 3 3 3 0 TFIIH C1-like domain Lar_restr_allev PF14354.1 EGC33646.1 - 3.2 8.1 10.6 0.24 11.7 1.0 2.7 1 1 1 2 2 2 0 Restriction alleviation protein Lar Zn_Tnp_IS91 PF14319.1 EGC33646.1 - 5.6 6.5 11.6 3.4 7.2 1.8 2.8 1 1 1 2 2 2 0 Transposase zinc-binding domain Ogr_Delta PF04606.7 EGC33646.1 - 6.6 6.4 12.9 0.12 12.0 1.7 2.7 2 1 0 2 2 2 0 Ogr/Delta-like zinc finger Zn-ribbon_8 PF09723.5 EGC33646.1 - 7.2 6.6 12.7 12 5.9 0.0 3.7 3 1 0 3 3 3 0 Zinc ribbon domain zf-FPG_IleRS PF06827.9 EGC33646.1 - 7.6 6.2 7.2 4.9 6.9 0.3 2.8 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS Zn_ribbon_recom PF13408.1 EGC33646.1 - 8.9 6.6 11.2 0.42 10.9 1.9 2.5 2 1 0 2 2 2 0 Recombinase zinc beta ribbon domain OrfB_Zn_ribbon PF07282.6 EGC33646.1 - 9.5 5.9 10.2 8.3 6.1 0.7 2.6 2 1 0 2 2 2 0 Putative transposase DNA-binding domain Hexapep PF00132.19 EGC33647.1 - 3.9e-06 26.1 9.1 5.1e-05 22.5 0.7 4.7 3 2 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) Fucokinase PF07959.7 EGC33647.1 - 0.33 9.4 7.5 0.19 10.2 0.7 2.1 1 1 0 2 2 2 0 L-fucokinase Phosducin PF02114.11 EGC33648.1 - 7.4e-16 57.6 1.5 7.4e-16 57.6 1.0 1.4 1 1 0 1 1 1 1 Phosducin TPR_21 PF09976.4 EGC33648.1 - 0.011 15.7 2.5 0.022 14.6 1.8 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat PepSY_TM_2 PF13703.1 EGC33649.1 - 5.6e-07 29.6 7.7 0.00045 20.3 1.6 3.1 3 0 0 3 3 3 2 PepSY-associated TM helix DUF221 PF02714.10 EGC33649.1 - 6.4e-05 21.9 3.2 6.4e-05 21.9 2.2 1.5 2 0 0 2 2 2 1 Domain of unknown function DUF221 Cytochrom_B_N PF00033.14 EGC33649.1 - 0.056 12.7 14.3 0.063 12.6 2.5 2.1 1 1 1 2 2 2 0 Cytochrome b(N-terminal)/b6/petB PepSY_TM_1 PF13172.1 EGC33649.1 - 0.057 13.1 0.3 0.057 13.1 0.2 4.0 5 0 0 5 5 5 0 PepSY-associated TM helix Ni_hydr_CYTB PF01292.15 EGC33649.1 - 0.13 11.6 10.5 0.036 13.4 2.6 2.4 1 1 0 2 2 2 0 Prokaryotic cytochrome b561 60KD_IMP PF02096.15 EGC33649.1 - 0.84 9.2 4.4 0.47 10.0 0.1 2.2 1 1 1 2 2 2 0 60Kd inner membrane protein PepSY_TM PF03929.11 EGC33649.1 - 5.5 7.5 10.8 3.1 8.3 0.2 3.5 4 1 0 4 4 4 0 PepSY-associated TM helix SR-25 PF10500.4 EGC33650.1 - 2.4 7.5 7.5 4.6 6.6 5.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF4448 PF14610.1 EGC33651.1 - 0.03 13.8 0.7 0.057 12.8 0.2 1.6 1 1 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3357 PF11837.3 EGC33651.1 - 0.086 12.6 0.0 0.14 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) ABC2_membrane_2 PF12679.2 EGC33651.1 - 0.11 11.3 2.3 0.14 11.0 1.6 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein COX7C PF02935.11 EGC33651.1 - 0.17 11.7 1.1 0.31 10.8 0.8 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase subunit VIIc Syndecan PF01034.15 EGC33651.1 - 0.2 11.2 1.1 0.38 10.4 0.7 1.4 1 0 0 1 1 1 0 Syndecan domain FNIP PF05725.7 EGC33653.1 - 2e-27 94.8 29.0 4.4e-11 42.5 0.3 6.2 4 1 2 6 6 6 4 FNIP Repeat Fe_dep_repr_C PF02742.10 EGC33653.1 - 0.096 12.3 0.4 8.8 6.1 0.1 2.4 2 0 0 2 2 2 0 Iron dependent repressor, metal binding and dimerisation domain F-box-like PF12937.2 EGC33655.1 - 4.5e-07 29.4 0.6 2.6e-06 27.0 0.1 2.4 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC33655.1 - 0.00011 21.7 0.0 0.00025 20.6 0.0 1.6 1 0 0 1 1 1 1 F-box domain PA26 PF04636.8 EGC33655.1 - 0.016 13.9 2.9 0.028 13.1 2.0 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) DUF1510 PF07423.6 EGC33655.1 - 0.051 12.9 23.6 0.021 14.1 11.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 EGC33655.1 - 0.09 12.6 6.4 0.23 11.3 3.9 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 EGC33655.1 - 4.6 5.5 9.8 6.4 5.0 6.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2201_N PF13203.1 EGC33655.1 - 6.5 5.8 7.4 2 7.4 2.9 1.7 2 0 0 2 2 2 0 Putative metallopeptidase domain Metallophos PF00149.23 EGC33656.1 - 3.4e-18 65.7 5.8 1.1e-17 64.1 4.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC33656.1 - 4.8e-10 39.4 0.0 6.8e-10 38.9 0.0 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Claudin_2 PF13903.1 EGC33657.1 - 0.00021 21.0 2.4 0.00021 21.0 1.6 2.6 1 1 1 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction ABC2_membrane_4 PF12730.2 EGC33657.1 - 0.0077 15.4 14.4 0.019 14.1 9.7 1.8 1 1 0 1 1 1 1 ABC-2 family transporter protein Oxidored_q3 PF00499.15 EGC33657.1 - 0.015 15.0 11.3 0.015 15.1 5.6 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Presenilin PF01080.12 EGC33657.1 - 0.019 13.7 3.5 0.029 13.2 2.4 1.2 1 0 0 1 1 1 0 Presenilin Pox_P21 PF05313.7 EGC33657.1 - 0.21 10.8 3.9 0.044 13.0 0.5 1.5 2 0 0 2 2 2 0 Poxvirus P21 membrane protein Tic20 PF09685.5 EGC33657.1 - 9 6.3 14.8 0.25 11.3 2.1 2.8 3 0 0 3 3 3 0 Tic20-like protein ArfGap PF01412.13 EGC33658.1 - 7.6e-27 93.4 4.9 7.6e-27 93.4 3.4 3.5 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf SH3_9 PF14604.1 EGC33658.1 - 4.9e-13 48.4 0.1 1.1e-12 47.2 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC33658.1 - 1.6e-09 36.9 0.1 4.1e-09 35.6 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC33658.1 - 1.3e-05 24.6 0.0 2.5e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain PB1 PF00564.19 EGC33658.1 - 0.045 13.4 0.3 0.46 10.1 0.0 2.6 2 0 0 2 2 2 0 PB1 domain MFS_1 PF07690.11 EGC33659.1 - 3e-47 161.0 50.2 1.7e-37 128.9 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC33659.1 - 4.4e-05 22.2 36.7 0.00013 20.7 25.5 1.5 1 1 0 1 1 1 1 Sugar (and other) transporter OppC_N PF12911.2 EGC33659.1 - 0.017 14.4 4.7 0.37 10.2 0.0 4.0 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C MFS_3 PF05977.8 EGC33659.1 - 0.081 11.0 8.5 0.1 10.6 0.3 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector LptE PF04390.7 EGC33659.1 - 1 9.0 0.0 1 9.0 0.0 2.3 2 0 0 2 2 2 0 Lipopolysaccharide-assembly IF-2B PF01008.12 EGC33660.1 - 1.6e-81 273.4 0.2 1.9e-81 273.1 0.1 1.1 1 0 0 1 1 1 1 Initiation factor 2 subunit family PUF PF00806.14 EGC33660.1 - 0.06 12.8 0.1 0.23 10.9 0.0 2.1 1 0 0 1 1 1 0 Pumilio-family RNA binding repeat Usp PF00582.21 EGC33661.1 - 2.9e-15 56.6 0.0 3.7e-15 56.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family MGS PF02142.17 EGC33661.1 - 0.0014 18.5 0.1 0.0021 17.9 0.1 1.4 1 1 0 1 1 1 1 MGS-like domain SipA PF09052.5 EGC33661.1 - 0.05 12.0 0.1 0.055 11.8 0.1 1.0 1 0 0 1 1 1 0 Salmonella invasion protein A Hus1 PF04005.7 EGC33662.1 - 1.8e-68 230.6 8.3 3.8e-68 229.5 5.8 1.5 1 1 0 1 1 1 1 Hus1-like protein Redoxin PF08534.5 EGC33663.1 - 1.5e-31 108.9 0.0 1.7e-31 108.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA PF00578.16 EGC33663.1 - 1.9e-09 37.2 0.0 2.3e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family FKBP_C PF00254.23 EGC33664.1 - 7.8e-27 93.1 0.2 1.2e-26 92.5 0.1 1.3 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF2232 PF09991.4 EGC33664.1 - 0.07 12.1 0.8 0.3 10.0 0.1 1.9 2 0 0 2 2 2 0 Predicted membrane protein (DUF2232) PA14 PF07691.7 EGC33665.1 - 2.7e-11 43.2 0.6 4.4e-11 42.6 0.0 1.6 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.13 EGC33665.1 - 0.00046 19.9 5.7 0.00046 19.9 4.0 9.8 10 1 0 10 10 10 4 Dictyostelium (slime mold) repeat PAXNEB PF05625.6 EGC33666.1 - 0.098 11.4 0.0 0.15 10.9 0.0 1.1 1 0 0 1 1 1 0 PAXNEB protein Chlam_PMP PF02415.12 EGC33666.1 - 0.19 12.0 45.2 1.9 8.9 0.6 8.5 7 1 0 7 7 7 0 Chlamydia polymorphic membrane protein (Chlamydia_PMP) repeat Trypan_PARP PF05887.6 EGC33667.1 - 1.2 8.8 16.7 0.28 11.0 4.5 2.1 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) DUF605 PF04652.11 EGC33667.1 - 2.5 7.4 23.1 2.9 7.2 16.0 1.0 1 0 0 1 1 1 0 Vta1 like Peptidase_M3_N PF08439.5 EGC33670.1 - 0.024 14.6 4.2 0.024 14.6 2.9 2.8 2 1 0 2 2 2 0 Oligopeptidase F DUF3753 PF12575.3 EGC33670.1 - 0.028 14.1 0.2 3.8 7.3 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3753) Seryl_tRNA_N PF02403.17 EGC33670.1 - 0.25 11.3 40.9 0.42 10.6 12.8 2.3 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF3040 PF11239.3 EGC33670.1 - 0.84 9.7 2.2 30 4.7 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF3040) Jnk-SapK_ap_N PF09744.4 EGC33670.1 - 1.3 8.9 45.3 0.051 13.5 14.8 3.0 1 1 2 3 3 3 0 JNK_SAPK-associated protein-1 Hemerythrin PF01814.18 EGC33670.1 - 1.5 8.9 8.0 13 5.9 4.0 2.7 1 1 1 2 2 2 0 Hemerythrin HHE cation binding domain Mto2_bdg PF12808.2 EGC33670.1 - 2.4 8.3 25.9 0.72 9.9 1.0 3.8 3 1 0 3 3 3 0 Micro-tubular organiser Mto1 C-term Mto2-binding region EB1 PF03271.12 EGC33670.1 - 4.1 7.5 13.7 0.24 11.5 0.5 3.5 2 1 0 2 2 2 0 EB1-like C-terminal motif BLOC1_2 PF10046.4 EGC33670.1 - 4.8 7.3 43.2 0.26 11.4 7.4 3.4 1 1 2 3 3 3 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 PRA1 PF03208.14 EGC33671.1 - 0.011 15.0 6.4 0.088 12.1 4.5 2.0 1 1 0 1 1 1 0 PRA1 family protein Pex24p PF06398.6 EGC33671.1 - 1.3 7.7 7.9 2.3 6.9 5.5 1.4 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin VIT1 PF01988.14 EGC33671.1 - 2.9 7.3 10.5 4 6.8 7.3 1.2 1 0 0 1 1 1 0 VIT family ABC2_membrane_4 PF12730.2 EGC33671.1 - 8.7 5.4 25.1 12 5.0 17.4 1.3 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF605 PF04652.11 EGC33672.1 - 0.033 13.5 8.9 0.054 12.8 6.2 1.3 1 0 0 1 1 1 0 Vta1 like DUF874 PF05917.6 EGC33673.1 - 0.0052 15.7 5.7 0.0071 15.2 3.9 1.3 1 0 0 1 1 1 1 Helicobacter pylori protein of unknown function (DUF874) IncA PF04156.9 EGC33673.1 - 0.014 15.0 0.2 0.025 14.2 0.1 1.3 1 0 0 1 1 1 0 IncA protein Shisa PF13908.1 EGC33673.1 - 0.016 15.3 0.5 0.026 14.7 0.3 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 EGC33673.1 - 0.34 10.1 4.0 0.66 9.2 2.8 1.4 1 0 0 1 1 1 0 Tetraspanin family DUF1183 PF06682.7 EGC33673.1 - 0.59 9.6 9.4 0.22 11.0 4.7 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) COPI_assoc PF08507.5 EGC33673.1 - 2.1 8.0 4.4 1.5 8.5 0.2 2.5 2 1 0 2 2 2 0 COPI associated protein BAF1_ABF1 PF04684.8 EGC33673.1 - 3.5 6.3 19.1 4.9 5.8 13.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2215 PF10225.4 EGC33673.1 - 7.8 5.8 6.3 20 4.5 4.4 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) GTP_EFTU PF00009.22 EGC33675.1 - 2.5e-43 147.6 0.0 3.5e-43 147.2 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGC33675.1 - 1.5e-18 66.8 0.1 6.2e-18 64.8 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGC33675.1 - 2.4e-06 27.5 0.4 9.5e-06 25.6 0.3 2.1 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC33675.1 - 5.7e-05 23.0 0.0 0.00028 20.8 0.0 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC33675.1 - 0.00038 19.2 0.3 0.00073 18.3 0.2 1.5 1 0 0 1 1 1 1 G-protein alpha subunit PAM2 PF07145.10 EGC33675.1 - 0.0028 17.0 0.6 0.0095 15.3 0.4 1.9 1 0 0 1 1 1 1 Ataxin-2 C-terminal region GTP_EFTU_D4 PF14578.1 EGC33675.1 - 0.048 13.3 0.4 0.13 11.8 0.3 1.7 1 0 0 1 1 1 0 Elongation factor Tu domain 4 Miro PF08477.8 EGC33675.1 - 0.13 12.7 0.9 0.34 11.4 0.0 2.2 2 1 0 2 2 2 0 Miro-like protein CDC37_M PF08565.6 EGC33675.1 - 0.31 10.5 2.9 0.67 9.4 2.0 1.5 1 0 0 1 1 1 0 Cdc37 Hsp90 binding domain ANTH PF07651.11 EGC33676.1 - 1.7e-52 177.8 0.6 3.1e-52 176.9 0.4 1.5 1 0 0 1 1 1 1 ANTH domain ENTH PF01417.15 EGC33676.1 - 4.6e-07 29.7 0.0 9.9e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 ENTH domain DUF2992 PF11208.3 EGC33677.1 - 1 9.2 18.5 1.1 9.1 12.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2992) DUF1366 PF07104.6 EGC33677.1 - 2 8.0 14.3 2.3 7.8 9.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1366) Cytadhesin_P30 PF07271.6 EGC33677.1 - 4 6.6 8.4 4.7 6.3 5.8 1.2 1 0 0 1 1 1 0 Cytadhesin P30/P32 DUF4337 PF14235.1 EGC33677.1 - 6.3 6.6 13.9 7 6.4 9.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) YjcQ PF09639.5 EGC33679.1 - 0.034 14.2 0.9 0.044 13.8 0.7 1.2 1 0 0 1 1 1 0 YjcQ protein UBA PF00627.26 EGC33679.1 - 0.18 11.7 2.9 1.6 8.6 0.2 2.3 2 0 0 2 2 2 0 UBA/TS-N domain LRS4 PF10422.4 EGC33679.1 - 0.57 9.4 5.3 0.63 9.3 3.7 1.1 1 0 0 1 1 1 0 Monopolin complex subunit LRS4 Peptidase_C6 PF00851.13 EGC33679.1 - 0.67 8.5 3.8 0.73 8.3 2.6 1.0 1 0 0 1 1 1 0 Helper component proteinase SlyX PF04102.7 EGC33679.1 - 2.4 8.6 5.2 1.1 9.6 0.7 2.1 1 1 1 2 2 2 0 SlyX SapB_1 PF05184.10 EGC33679.1 - 9.8 6.1 9.1 0.16 11.8 1.0 2.0 3 0 0 3 3 3 0 Saposin-like type B, region 1 DUF972 PF06156.8 EGC33680.1 - 0.0072 16.6 6.6 0.62 10.4 0.5 2.4 1 1 1 2 2 2 2 Protein of unknown function (DUF972) Toxin_trans PF07952.7 EGC33680.1 - 0.45 9.3 7.9 0.56 9.0 5.1 1.5 1 1 0 1 1 1 0 Clostridium neurotoxin, Translocation domain DUF2317 PF10079.4 EGC33681.1 - 0.019 13.6 1.1 0.024 13.2 0.7 1.0 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) DUF2457 PF10446.4 EGC33681.1 - 0.34 9.5 17.2 0.38 9.4 11.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Nop14 PF04147.7 EGC33681.1 - 0.52 8.1 8.8 0.64 7.8 6.1 1.1 1 0 0 1 1 1 0 Nop14-like family RhoGAP PF00620.22 EGC33682.1 - 1.2e-34 119.1 6.6 4.1e-34 117.3 0.3 4.0 4 0 0 4 4 4 1 RhoGAP domain RhoGEF PF00621.15 EGC33682.1 - 2.1e-31 109.1 0.4 2.1e-31 109.1 0.3 3.3 5 0 0 5 5 5 1 RhoGEF domain Abhydrolase_6 PF12697.2 EGC33683.1 - 5e-26 91.9 0.0 8.8e-26 91.1 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC33683.1 - 3.7e-16 59.1 0.0 6.5e-16 58.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC33683.1 - 3.2e-15 56.3 0.0 8.2e-14 51.7 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold PGAP1 PF07819.8 EGC33683.1 - 1.7e-08 34.3 0.1 2.9e-08 33.5 0.1 1.3 1 0 0 1 1 1 1 PGAP1-like protein Ndr PF03096.9 EGC33683.1 - 4.6e-06 25.3 0.0 1.5e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Ndr family Thioesterase PF00975.15 EGC33683.1 - 7.2e-05 23.1 0.0 0.0001 22.6 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EGC33683.1 - 0.00011 21.6 0.5 0.0003 20.1 0.2 1.7 2 0 0 2 2 2 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGC33683.1 - 0.00027 20.5 0.0 0.00048 19.7 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) Esterase PF00756.15 EGC33683.1 - 0.0022 17.4 0.0 0.0057 16.1 0.0 1.6 1 1 0 1 1 1 1 Putative esterase Hydrolase_4 PF12146.3 EGC33683.1 - 0.0091 15.8 0.0 0.017 14.9 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Chlorophyllase PF07224.6 EGC33683.1 - 0.016 14.0 0.0 0.033 12.9 0.0 1.5 2 0 0 2 2 2 0 Chlorophyllase BAAT_C PF08840.6 EGC33683.1 - 0.023 14.4 0.0 0.069 12.8 0.0 1.9 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal DLH PF01738.13 EGC33683.1 - 0.05 12.8 0.0 0.48 9.6 0.0 2.1 1 1 0 1 1 1 0 Dienelactone hydrolase family UPF0227 PF05728.7 EGC33683.1 - 0.11 12.1 0.0 0.16 11.7 0.0 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0227) Abhydrolase_6 PF12697.2 EGC33684.1 - 1.6e-31 109.9 0.0 2.1e-31 109.5 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC33684.1 - 8.3e-20 71.3 0.0 1.5e-18 67.1 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC33684.1 - 3e-17 62.7 0.0 7.1e-17 61.5 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGC33684.1 - 4.6e-08 32.9 0.0 9.2e-08 31.9 0.0 1.4 1 0 0 1 1 1 1 PGAP1-like protein DLH PF01738.13 EGC33684.1 - 1.2e-05 24.7 0.1 0.086 12.1 0.0 3.1 2 1 0 2 2 2 2 Dienelactone hydrolase family Esterase PF00756.15 EGC33684.1 - 0.00018 20.9 0.0 0.001 18.5 0.0 1.9 1 1 1 2 2 2 1 Putative esterase Lipase_3 PF01764.20 EGC33684.1 - 0.00035 20.2 0.0 0.00059 19.4 0.0 1.4 1 0 0 1 1 1 1 Lipase (class 3) Thioesterase PF00975.15 EGC33684.1 - 0.00077 19.7 0.0 0.0011 19.2 0.0 1.2 1 0 0 1 1 1 1 Thioesterase domain DUF676 PF05057.9 EGC33684.1 - 0.00083 18.7 0.1 0.0013 18.0 0.1 1.3 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Ndr PF03096.9 EGC33684.1 - 0.0021 16.6 0.0 0.0037 15.7 0.0 1.4 1 0 0 1 1 1 1 Ndr family DUF915 PF06028.6 EGC33684.1 - 0.016 14.2 0.1 0.11 11.6 0.0 2.2 2 0 0 2 2 2 0 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.6 EGC33684.1 - 0.018 14.7 0.0 0.056 13.1 0.0 1.8 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Chlorophyllase PF07224.6 EGC33684.1 - 0.032 13.0 0.0 0.049 12.4 0.0 1.2 1 0 0 1 1 1 0 Chlorophyllase Lipase_2 PF01674.13 EGC33684.1 - 0.033 13.4 0.1 1.3 8.2 0.1 2.6 2 1 0 2 2 2 0 Lipase (class 2) DUF2048 PF09752.4 EGC33684.1 - 0.037 12.8 0.0 0.34 9.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 EGC33684.1 - 0.041 13.7 0.0 0.1 12.4 0.0 1.6 1 0 0 1 1 1 0 Putative lysophospholipase DUF900 PF05990.7 EGC33684.1 - 0.11 11.7 0.0 0.18 11.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF900) Zot PF05707.7 EGC33685.1 - 0.12 11.8 0.0 0.14 11.6 0.0 1.1 1 0 0 1 1 1 0 Zonular occludens toxin (Zot) Pkinase PF00069.20 EGC33687.1 - 4.6e-53 180.0 0.1 4.6e-53 180.0 0.1 3.4 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33687.1 - 1.5e-28 99.5 0.0 1.5e-28 99.5 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGC33687.1 - 0.01 15.6 2.8 0.23 11.1 0.0 3.0 2 1 1 3 3 3 1 Phosphotransferase enzyme family COPIIcoated_ERV PF07970.7 EGC33688.1 - 7.5e-51 172.8 1.5 1e-50 172.4 1.1 1.2 1 0 0 1 1 1 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGC33688.1 - 4.1e-25 87.5 0.1 7.2e-25 86.8 0.1 1.3 1 0 0 1 1 1 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PAH PF02671.16 EGC33689.1 - 5.8e-44 147.4 15.7 2e-17 62.5 0.3 5.6 5 0 0 5 5 5 4 Paired amphipathic helix repeat Sin3_corepress PF08295.7 EGC33689.1 - 1.6e-41 140.1 0.0 3e-40 136.0 0.0 3.4 2 0 0 2 2 2 1 Sin3 family co-repressor Coiled PF05710.7 EGC33690.1 - 0.08 13.4 4.1 0.092 13.2 2.9 1.1 1 0 0 1 1 1 0 Coiled coil F-box PF00646.28 EGC33692.1 - 0.00024 20.6 0.2 0.00063 19.3 0.1 1.7 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGC33692.1 - 0.00095 18.8 0.1 0.0019 17.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like Nucleoplasmin PF03066.10 EGC33694.1 - 0.0033 16.9 0.2 0.004 16.6 0.2 1.2 1 0 0 1 1 1 1 Nucleoplasmin DDE_Tnp_4 PF13359.1 EGC33695.1 - 0.047 13.2 0.4 0.052 13.1 0.3 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease F-box PF00646.28 EGC33696.1 - 0.00022 20.7 0.2 0.00063 19.3 0.1 1.8 1 0 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGC33696.1 - 0.00091 18.9 0.1 0.0019 17.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like FNIP PF05725.7 EGC33697.1 - 1.4e-150 489.0 72.8 3.7e-15 55.5 0.5 12.6 10 1 0 12 12 12 12 FNIP Repeat MerC PF03203.9 EGC33697.1 - 2.3e-05 24.7 1.0 11 6.3 0.0 6.0 3 3 2 6 6 6 2 MerC mercury resistance protein DUF1769 PF08588.5 EGC33697.1 - 3.1e-05 23.8 32.0 8.7 6.3 0.1 12.2 5 4 10 15 15 15 3 Protein of unknown function (DUF1769) ADH_zinc_N PF00107.21 EGC33697.1 - 0.015 14.8 0.1 27 4.3 0.0 4.5 3 3 3 7 7 7 0 Zinc-binding dehydrogenase L_lac_phage_MSP PF06488.6 EGC33697.1 - 1.2 8.0 7.0 32 3.4 0.1 4.9 5 1 1 6 6 6 0 Lactococcus lactis bacteriophage major structural protein Tox-MPTase5 PF15641.1 EGC33699.1 - 0.13 12.2 0.0 0.23 11.4 0.0 1.4 1 0 0 1 1 1 0 Metallopeptidase toxin 5 MOR2-PAG1_N PF14222.1 EGC33699.1 - 0.93 8.0 3.6 1.1 7.8 2.5 1.2 1 0 0 1 1 1 0 Cell morphogenesis N-terminal DUF3703 PF12487.3 EGC33701.1 - 1.2 8.8 9.3 1.6 8.4 6.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3703) Pkinase PF00069.20 EGC33703.1 - 3.1e-42 144.5 0.1 3.1e-42 144.5 0.0 2.2 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33703.1 - 8.9e-38 129.8 0.2 1.8e-37 128.8 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase Daxx PF03344.10 EGC33703.1 - 0.0049 15.4 14.8 0.0074 14.8 10.2 1.2 1 0 0 1 1 1 1 Daxx Family APH PF01636.18 EGC33703.1 - 0.23 11.1 0.0 0.37 10.4 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BUD22 PF09073.5 EGC33703.1 - 1.7 7.6 23.7 2.5 7.0 0.1 2.3 2 0 0 2 2 2 0 BUD22 Pkinase PF00069.20 EGC33705.1 - 1.6e-25 89.7 5.9 3.8e-22 78.6 0.3 3.1 1 1 1 2 2 2 2 Protein kinase domain FNIP PF05725.7 EGC33705.1 - 1.5e-13 50.4 30.4 6.5e-05 22.7 0.1 5.9 1 1 6 7 7 7 5 FNIP Repeat Pkinase_Tyr PF07714.12 EGC33705.1 - 8.3e-12 44.7 1.2 5.8e-07 28.8 0.1 3.1 1 1 1 2 2 2 2 Protein tyrosine kinase UPF0253 PF06786.7 EGC33705.1 - 0.037 14.1 0.0 2.5 8.2 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0253) DUF2195 PF09961.4 EGC33705.1 - 0.14 11.9 0.1 0.34 10.7 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) FNIP PF05725.7 EGC33706.1 - 1.3e-98 322.6 34.1 2.1e-14 53.1 0.0 7.0 1 1 5 9 9 9 9 FNIP Repeat LRR_8 PF13855.1 EGC33706.1 - 0.0083 15.8 1.3 1.6 8.5 0.0 4.2 2 2 2 4 4 4 1 Leucine rich repeat DUF1769 PF08588.5 EGC33706.1 - 0.049 13.5 17.4 8.5 6.4 0.2 6.8 3 3 5 8 8 8 0 Protein of unknown function (DUF1769) LRR_6 PF13516.1 EGC33706.1 - 0.079 13.0 26.8 25 5.3 0.2 10.2 11 1 1 12 12 12 0 Leucine Rich repeat DUF1662 PF07878.6 EGC33706.1 - 0.51 10.1 3.2 1.7e+02 2.0 0.0 5.1 6 0 0 6 6 6 0 Protein of unknown function (DUF1662) Adap_comp_sub PF00928.16 EGC33709.1 - 3.4e-93 311.5 0.0 4.3e-93 311.2 0.0 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGC33709.1 - 3e-08 33.4 0.7 5.3e-08 32.6 0.5 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain DDHD PF02862.12 EGC33710.1 - 6.1e-09 36.0 9.1 1.4e-08 34.8 6.3 1.6 1 1 0 1 1 1 1 DDHD domain Glyco_transf_8 PF01501.15 EGC33711.1 - 3.4e-09 36.4 7.1 4.6e-08 32.7 0.3 2.2 2 0 0 2 2 2 2 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGC33711.1 - 0.034 13.4 0.2 0.059 12.7 0.1 1.3 1 0 0 1 1 1 0 Mannosyltransferase putative Citrate_synt PF00285.16 EGC33712.1 - 1.7e-126 421.7 0.0 2.2e-126 421.3 0.0 1.1 1 0 0 1 1 1 1 Citrate synthase Ras PF00071.17 EGC33713.1 - 2.1e-54 183.2 0.0 2.4e-54 183.0 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33713.1 - 9.3e-17 61.6 0.0 1.5e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC33713.1 - 2.2e-09 36.8 0.0 2.9e-09 36.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC33713.1 - 0.00025 20.5 0.0 0.0024 17.3 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC33713.1 - 0.054 13.4 0.0 0.074 13.0 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase LRR_8 PF13855.1 EGC33714.1 - 6.3e-08 32.2 44.0 5.3e-06 26.0 7.5 5.1 4 1 1 5 5 5 3 Leucine rich repeat LRR_4 PF12799.2 EGC33714.1 - 1.5e-07 30.8 33.3 9.8e-05 21.8 1.6 7.4 6 1 3 9 9 9 6 Leucine Rich repeats (2 copies) CPSase_sm_chain PF00988.17 EGC33716.1 - 0.1 12.0 0.1 0.13 11.7 0.1 1.2 1 0 0 1 1 1 0 Carbamoyl-phosphate synthase small chain, CPSase domain Ank_2 PF12796.2 EGC33717.1 - 8.8e-36 122.1 0.1 5.1e-23 81.2 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC33717.1 - 4.3e-30 101.9 0.9 1.2e-09 37.5 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EGC33717.1 - 1.1e-28 99.0 1.4 1.6e-11 44.3 0.0 3.6 1 1 3 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC33717.1 - 1.6e-26 91.7 3.6 1.9e-09 37.4 0.0 4.0 1 1 3 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC33717.1 - 1.1e-20 71.6 0.4 1.1e-05 25.2 0.0 4.1 4 0 0 4 4 4 4 Ankyrin repeat Pkinase PF00069.20 EGC33718.1 - 5.2e-28 97.8 0.0 2.4e-27 95.7 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain DSPc PF00782.15 EGC33718.1 - 6.1e-26 90.5 3.2 6.3e-26 90.5 0.0 2.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Pkinase_Tyr PF07714.12 EGC33718.1 - 1.2e-12 47.4 0.0 2.2e-12 46.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase tRNA_Me_trans PF03054.11 EGC33720.1 - 1.8e-97 326.0 0.2 2.3e-97 325.7 0.1 1.0 1 0 0 1 1 1 1 tRNA methyl transferase NAD_synthase PF02540.12 EGC33720.1 - 0.0004 19.3 0.0 0.0023 16.8 0.0 2.1 2 1 0 2 2 2 1 NAD synthase ThiI PF02568.9 EGC33720.1 - 0.046 13.1 0.1 0.69 9.3 0.0 2.2 2 0 0 2 2 2 0 Thiamine biosynthesis protein (ThiI) Asn_synthase PF00733.16 EGC33720.1 - 0.052 13.0 0.0 0.081 12.4 0.0 1.2 1 0 0 1 1 1 0 Asparagine synthase ATP_bind_3 PF01171.15 EGC33720.1 - 0.054 12.9 0.0 0.36 10.3 0.0 2.1 1 1 0 1 1 1 0 PP-loop family Dzip-like_N PF13815.1 EGC33721.1 - 0.0087 15.8 0.1 0.015 15.1 0.1 1.3 1 0 0 1 1 1 1 Iguana/Dzip1-like DAZ-interacting protein N-terminal WAPL PF07814.8 EGC33721.1 - 0.087 11.5 2.1 0.13 10.9 1.5 1.2 1 0 0 1 1 1 0 Wings apart-like protein regulation of heterochromatin PA14 PF07691.7 EGC33722.1 - 1.8e-12 47.1 0.7 3.8e-12 46.0 0.2 1.8 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.13 EGC33722.1 - 0.0065 16.2 11.8 0.0065 16.2 8.2 6.3 6 0 0 6 6 6 2 Dictyostelium (slime mold) repeat Ribosomal_S3Ae PF01015.13 EGC33723.1 - 2.4e-73 245.6 2.1 3.1e-73 245.2 1.5 1.1 1 0 0 1 1 1 1 Ribosomal S3Ae family Abhydro_lipase PF04083.11 EGC33723.1 - 0.024 13.9 0.0 0.052 12.9 0.0 1.6 1 0 0 1 1 1 0 Partial alpha/beta-hydrolase lipase region Mito_carr PF00153.22 EGC33724.1 - 4.7e-75 247.4 1.1 7.9e-28 96.0 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein NYAP_C PF15452.1 EGC33724.1 - 0.0098 14.9 0.3 0.03 13.3 0.0 1.8 2 0 0 2 2 2 1 Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter PA14 PF07691.7 EGC33725.1 - 5.3e-12 45.6 0.1 9.2e-12 44.8 0.1 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC33725.1 - 3e-08 33.3 21.2 5.1e-06 26.1 6.0 6.9 7 0 0 7 7 7 4 Dictyostelium (slime mold) repeat zf-RING_2 PF13639.1 EGC33728.1 - 3.9e-09 36.2 9.3 7e-09 35.3 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC33728.1 - 1.4e-08 34.2 11.7 3.8e-08 32.8 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33728.1 - 1.4e-06 28.2 6.9 3.9e-06 26.8 4.8 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC33728.1 - 5.6e-06 25.9 7.4 9.7e-06 25.1 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33728.1 - 1.3e-05 25.1 9.8 2.4e-05 24.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33728.1 - 2.6e-05 23.8 10.7 5.5e-05 22.8 7.4 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC33728.1 - 0.00034 20.4 8.8 0.00096 18.9 6.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC33728.1 - 0.0051 16.3 9.5 0.012 15.1 6.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EGC33728.1 - 0.027 14.1 1.7 0.027 14.1 1.2 2.5 2 1 0 2 2 1 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 EGC33728.1 - 0.034 14.0 3.6 0.064 13.1 2.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC33728.1 - 0.045 13.2 8.9 0.08 12.4 6.2 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGC33728.1 - 0.13 11.9 5.9 0.44 10.3 4.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger Nop14 PF04147.7 EGC33728.1 - 0.58 8.0 36.0 0.041 11.8 18.0 2.2 2 1 0 2 2 2 0 Nop14-like family Gpi16 PF04113.9 EGC33729.1 - 1.6e-13 49.5 0.0 1.7e-13 49.5 0.0 1.0 1 0 0 1 1 1 1 Gpi16 subunit, GPI transamidase component MFS_1 PF07690.11 EGC33731.1 - 1e-23 83.6 41.3 1e-22 80.3 5.4 2.9 2 1 0 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC33731.1 - 7.7e-12 44.5 10.0 7.7e-12 44.5 6.9 2.5 2 1 0 2 2 2 1 Sugar (and other) transporter HTH_29 PF13551.1 EGC33732.1 - 2.8e-08 33.8 0.9 7.8e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 Winged helix-turn helix HTH_28 PF13518.1 EGC33732.1 - 1.2e-05 25.1 0.2 4.7e-05 23.2 0.1 2.0 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_23 PF13384.1 EGC33732.1 - 0.00014 21.3 1.4 0.0004 19.9 0.0 2.1 2 0 0 2 2 2 1 Homeodomain-like domain HTH_Tnp_1 PF01527.15 EGC33732.1 - 0.00064 19.6 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Transposase CENP-B_N PF04218.8 EGC33732.1 - 0.00097 18.5 0.1 0.0028 17.0 0.0 1.7 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_psq PF05225.11 EGC33732.1 - 0.0099 15.4 0.0 0.022 14.3 0.0 1.5 1 0 0 1 1 1 1 helix-turn-helix, Psq domain HTH_Tnp_ISL3 PF13542.1 EGC33732.1 - 0.036 13.2 0.1 0.084 12.0 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain of transposase family ISL3 HTH_11 PF08279.7 EGC33732.1 - 0.072 12.7 0.7 0.21 11.2 0.1 2.0 2 0 0 2 2 2 0 HTH domain HTH_26 PF13443.1 EGC33732.1 - 0.072 13.3 0.1 0.16 12.1 0.1 1.5 1 0 0 1 1 1 0 Cro/C1-type HTH DNA-binding domain DEAD PF00270.24 EGC33733.1 - 1.4e-45 154.8 0.0 5.3e-44 149.6 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase SPRY PF00622.23 EGC33733.1 - 1.8e-24 86.1 0.5 3.7e-24 85.1 0.4 1.5 1 0 0 1 1 1 1 SPRY domain Helicase_C PF00271.26 EGC33733.1 - 1.2e-20 73.1 0.0 2.5e-20 72.0 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1253 PF06862.7 EGC33733.1 - 0.001 17.6 0.5 3.3 6.0 0.0 3.1 3 0 0 3 3 3 3 Protein of unknown function (DUF1253) CMS1 PF14617.1 EGC33733.1 - 0.14 11.1 0.0 0.14 11.1 0.0 2.3 3 0 0 3 3 3 0 U3-containing 90S pre-ribosomal complex subunit ketoacyl-synt PF00109.21 EGC33734.1 - 2.6e-64 217.1 0.0 4.1e-64 216.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC33734.1 - 1e-45 156.4 0.0 1.7e-45 155.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC33734.1 - 9e-30 102.9 0.0 8.2e-29 99.8 0.0 2.5 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC33734.1 - 7.6e-26 90.8 0.0 1.4e-25 90.0 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC33734.1 - 1.5e-21 76.6 0.0 1.5e-21 76.6 0.0 3.9 4 0 0 4 4 3 1 Methyltransferase domain adh_short PF00106.20 EGC33734.1 - 6.3e-18 65.2 0.0 1.4e-17 64.1 0.0 1.6 2 0 0 2 2 1 1 short chain dehydrogenase PS-DH PF14765.1 EGC33734.1 - 2e-17 63.2 0.0 2.8e-17 62.8 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC33734.1 - 3e-08 34.5 0.0 6.9e-08 33.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC33734.1 - 2.1e-07 30.8 0.0 5.9e-07 29.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC33734.1 - 5.8e-07 29.9 0.0 2.5e-06 27.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGC33734.1 - 6.6e-07 29.0 0.1 1.5e-06 27.9 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EGC33734.1 - 9.2e-05 21.5 0.1 0.00033 19.7 0.0 1.9 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC33734.1 - 9.8e-05 22.9 0.0 0.00052 20.5 0.0 2.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EGC33734.1 - 0.0034 16.8 0.1 0.0074 15.7 0.0 1.6 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGC33734.1 - 0.0081 16.4 0.8 0.023 14.9 0.5 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3837 PF12939.2 EGC33736.1 - 0.0055 16.6 0.3 0.008 16.1 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3837) DUF4145 PF13643.1 EGC33736.1 - 0.013 15.3 0.2 0.025 14.4 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4145) ABC_membrane_3 PF13748.1 EGC33737.1 - 0.19 10.7 5.0 0.29 10.1 3.4 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region P5-ATPase PF12409.3 EGC33737.1 - 0.57 10.0 5.3 1 9.2 3.7 1.5 1 1 0 1 1 1 0 P5-type ATPase cation transporter Chromo PF00385.19 EGC33739.1 - 4.1e-09 35.9 0.3 7.8e-09 35.0 0.2 1.5 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC33739.1 - 0.01 15.5 1.8 0.018 14.7 1.2 1.4 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-RING_2 PF13639.1 EGC33740.1 - 3.3e-09 36.4 9.3 5.8e-09 35.6 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC33740.1 - 1.4e-08 34.2 11.7 4e-08 32.7 8.1 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33740.1 - 3.5e-07 30.2 4.5 9.4e-07 28.8 3.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC33740.1 - 4.2e-06 26.3 6.5 7e-06 25.6 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33740.1 - 1.4e-05 25.0 9.8 2.5e-05 24.2 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33740.1 - 3e-05 23.6 10.7 5.7e-05 22.7 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC33740.1 - 0.00037 20.2 8.8 0.001 18.9 6.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING CAF-1_p150 PF11600.3 EGC33740.1 - 0.0022 17.4 17.5 0.0022 17.4 12.2 4.1 4 1 1 5 5 4 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Prothymosin PF03247.9 EGC33740.1 - 0.0045 17.1 13.3 0.0045 17.1 9.2 5.5 3 2 1 4 4 1 1 Prothymosin/parathymosin family zf-RING_4 PF14570.1 EGC33740.1 - 0.0058 16.1 9.5 0.012 15.1 6.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC33740.1 - 0.019 14.8 2.9 0.037 13.8 2.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC33740.1 - 0.047 13.2 8.5 0.081 12.4 5.9 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGC33740.1 - 0.15 11.8 5.9 0.46 10.2 4.1 1.9 1 0 0 1 1 1 0 RING-type zinc-finger FYDLN_acid PF09538.5 EGC33740.1 - 0.28 11.7 0.0 0.28 11.7 0.0 4.6 4 1 0 4 4 4 0 Protein of unknown function (FYDLN_acid) DUF1272 PF06906.6 EGC33740.1 - 0.79 9.6 5.8 1.6 8.6 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) FNIP PF05725.7 EGC33741.1 - 1.3e-05 25.0 10.3 1.3e-05 25.0 7.2 12.1 9 2 3 12 12 12 5 FNIP Repeat GOLD_2 PF13897.1 EGC33741.1 - 0.026 14.7 0.8 0.059 13.5 0.5 1.6 1 0 0 1 1 1 0 Golgi-dynamics membrane-trafficking Gemini_AC4_5_2 PF08464.5 EGC33741.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Geminivirus AC4/5 conserved region C9orf72-like PF15019.1 EGC33742.1 - 2.2e-26 92.5 2.0 2.8e-26 92.2 1.4 1.2 1 0 0 1 1 1 1 C9orf72-like protein family COX5B PF01215.14 EGC33743.1 - 4e-39 133.3 0.0 4.8e-39 133.1 0.0 1.1 1 0 0 1 1 1 1 Cytochrome c oxidase subunit Vb HPP PF04982.8 EGC33744.1 - 2.6e-40 136.9 8.5 2.6e-40 136.9 5.9 1.6 2 0 0 2 2 2 1 HPP family Wzy_C PF04932.10 EGC33744.1 - 2.7 7.7 8.2 14 5.3 5.7 2.1 1 1 0 1 1 1 0 O-Antigen ligase 2OG-FeII_Oxy_2 PF13532.1 EGC33746.1 - 0.00026 20.8 0.0 0.0011 18.8 0.0 1.8 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily RRM_1 PF00076.17 EGC33747.1 - 8.2e-21 73.4 0.1 2.3e-13 49.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC33747.1 - 4.3e-15 55.4 0.0 8.3e-10 38.5 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) G-patch PF01585.18 EGC33747.1 - 9.2e-13 47.7 3.0 2.1e-12 46.5 2.1 1.7 1 0 0 1 1 1 1 G-patch domain zf-RanBP PF00641.13 EGC33747.1 - 2.4e-06 26.5 5.2 6.3e-06 25.1 3.6 1.7 1 0 0 1 1 1 1 Zn-finger in Ran binding protein and others G-patch_2 PF12656.2 EGC33747.1 - 2.7e-06 27.1 0.4 2.7e-06 27.1 0.2 2.9 2 0 0 2 2 2 1 DExH-box splicing factor binding site RRM_5 PF13893.1 EGC33747.1 - 0.0001 22.0 0.1 0.033 14.0 0.1 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EGC33747.1 - 0.00017 21.3 26.7 0.00017 21.3 18.5 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF1777) EGF_2 PF07974.8 EGC33748.1 - 2.1e-10 40.6 50.6 0.00036 20.6 8.1 4.3 3 0 0 3 3 3 3 EGF-like domain hEGF PF12661.2 EGC33748.1 - 4.5e-06 26.3 25.3 0.039 14.0 1.2 5.3 4 0 0 4 4 4 3 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC33748.1 - 0.06 13.2 36.1 0.61 10.0 5.5 4.0 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EGC33748.1 - 6 6.9 38.8 2.1 8.3 4.8 4.7 3 1 0 3 3 3 0 EGF-like domain EGF_2 PF07974.8 EGC33749.1 - 4.4e-06 26.7 30.7 0.0004 20.4 8.1 3.0 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC33749.1 - 0.00031 20.6 11.4 0.043 13.8 1.2 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC33749.1 - 0.11 12.5 21.4 1.7 8.6 5.7 2.8 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC33750.1 - 1.4e-08 34.6 65.9 0.00047 20.2 8.1 4.9 4 0 0 4 4 4 3 EGF-like domain hEGF PF12661.2 EGC33750.1 - 0.0035 17.3 29.1 0.051 13.6 1.2 4.2 4 0 0 4 4 4 3 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC33750.1 - 0.9 9.5 48.7 0.94 9.4 3.8 4.8 4 0 0 4 4 4 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC33751.1 - 1.7e-09 37.6 49.9 0.00029 20.9 8.8 4.3 3 1 0 3 3 3 3 EGF-like domain hEGF PF12661.2 EGC33751.1 - 1.2e-05 25.0 23.3 0.04 13.9 1.2 4.7 4 0 0 4 4 4 3 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC33751.1 - 0.19 11.7 36.5 1.5 8.7 6.1 4.0 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC33752.1 - 0.00035 20.6 12.7 0.00035 20.6 8.8 2.9 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.19 EGC33752.1 - 0.096 12.6 24.3 1.3 8.9 7.0 2.8 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC33752.1 - 2.4 8.4 10.3 0.43 10.7 1.7 3.2 2 0 0 2 2 2 0 Human growth factor-like EGF Orn_Arg_deC_N PF02784.11 EGC33753.1 - 1.5e-71 240.5 0.0 2.3e-71 239.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGC33753.1 - 9.4e-33 112.3 0.0 2.5e-32 111.0 0.0 1.7 2 0 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain AP_endonuc_2 PF01261.19 EGC33753.1 - 0.00039 19.7 0.0 0.0008 18.7 0.0 1.5 2 0 0 2 2 2 1 Xylose isomerase-like TIM barrel LRR_4 PF12799.2 EGC33754.1 - 1.5e-08 34.0 12.5 2.3e-06 27.1 0.5 3.9 4 0 0 4 4 4 2 Leucine Rich repeats (2 copies) LRR_9 PF14580.1 EGC33754.1 - 1.5e-07 31.1 0.4 2.4e-05 23.9 0.4 3.1 1 1 1 2 2 2 1 Leucine-rich repeat LRR_1 PF00560.28 EGC33754.1 - 0.00056 19.5 5.8 0.56 10.4 0.1 4.5 3 1 0 3 3 3 2 Leucine Rich Repeat LRR_8 PF13855.1 EGC33754.1 - 0.0014 18.2 9.2 77 3.1 0.2 3.6 3 1 0 3 3 3 0 Leucine rich repeat LRR_6 PF13516.1 EGC33754.1 - 0.0017 18.2 7.5 3.6 7.9 0.1 4.3 4 0 0 4 4 4 2 Leucine Rich repeat LRR_7 PF13504.1 EGC33754.1 - 0.013 15.5 4.2 6.8 7.3 0.1 4.5 4 0 0 4 4 4 0 Leucine rich repeat PA26 PF04636.8 EGC33754.1 - 0.34 9.5 6.0 0.57 8.8 4.2 1.3 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) NARP1 PF12569.3 EGC33754.1 - 0.65 8.6 20.9 1.1 7.9 14.5 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 APG6 PF04111.7 EGC33754.1 - 0.87 8.5 18.9 0.21 10.5 10.9 1.6 2 0 0 2 2 2 0 Autophagy protein Apg6 DUF963 PF06131.6 EGC33754.1 - 1.1 8.5 8.0 0.13 11.5 2.4 1.7 2 0 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) Mannosyl_trans2 PF04188.8 EGC33755.1 - 2.2e-74 251.0 29.1 5.5e-41 140.9 6.9 2.4 2 1 0 2 2 2 2 Mannosyltransferase (PIG-V)) HSCB_C PF07743.8 EGC33756.1 - 5.8e-19 68.3 2.2 5.8e-19 68.3 1.5 2.2 2 0 0 2 2 2 1 HSCB C-terminal oligomerisation domain DnaJ PF00226.26 EGC33756.1 - 5.1e-08 32.5 1.4 1.3e-07 31.1 0.3 2.2 2 0 0 2 2 2 1 DnaJ domain TelA PF05816.6 EGC33756.1 - 0.0022 16.7 0.9 1.3 7.6 0.0 2.5 3 0 0 3 3 3 2 Toxic anion resistance protein (TelA) DZR PF12773.2 EGC33756.1 - 0.025 14.3 1.1 0.044 13.6 0.8 1.3 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGC33756.1 - 0.051 13.0 2.6 0.099 12.1 1.8 1.5 1 0 0 1 1 1 0 zinc-ribbon domain Seryl_tRNA_N PF02403.17 EGC33756.1 - 1.9 8.5 8.9 2.3 8.2 0.3 3.4 3 0 0 3 3 3 0 Seryl-tRNA synthetase N-terminal domain PfkB PF00294.19 EGC33757.1 - 5.6e-54 183.3 0.3 7e-54 182.9 0.2 1.0 1 0 0 1 1 1 1 pfkB family carbohydrate kinase Phos_pyr_kin PF08543.7 EGC33757.1 - 0.0088 15.2 0.2 0.019 14.1 0.0 1.6 2 0 0 2 2 2 1 Phosphomethylpyrimidine kinase ABC2_membrane PF01061.19 EGC33758.1 - 3.7e-85 284.3 60.1 1.4e-49 168.1 10.9 2.7 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC33758.1 - 1.5e-37 128.9 0.0 1.9e-18 67.1 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGC33758.1 - 2.6e-23 81.6 13.8 3.7e-21 74.7 0.0 3.2 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGC33758.1 - 2.6e-08 33.8 0.1 5.9e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGC33758.1 - 1.4e-07 30.8 59.5 1.7e-05 24.0 11.3 3.7 2 2 1 3 3 3 2 ABC-2 family transporter protein DUF258 PF03193.11 EGC33758.1 - 9.7e-07 28.1 0.0 0.00033 19.8 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGC33758.1 - 1e-06 28.9 1.4 0.044 13.7 0.0 4.2 5 0 0 5 5 5 2 AAA domain AAA_29 PF13555.1 EGC33758.1 - 2.7e-06 26.8 0.4 0.0022 17.4 0.1 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC33758.1 - 1.2e-05 24.8 0.4 0.00037 19.9 0.1 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC33758.1 - 2.1e-05 24.6 0.2 0.036 14.2 0.1 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGC33758.1 - 0.0002 21.6 0.1 0.4 11.0 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC33758.1 - 0.00027 20.9 0.0 0.28 11.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain cobW PF02492.14 EGC33758.1 - 0.00074 19.0 0.1 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGC33758.1 - 0.0012 18.7 0.1 0.49 10.2 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC33758.1 - 0.002 18.9 0.1 0.31 11.8 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGC33758.1 - 0.0043 16.9 0.0 1.5 8.7 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGC33758.1 - 0.0047 16.4 0.1 0.62 9.5 0.0 2.3 2 0 0 2 2 2 1 FtsK/SpoIIIE family Miro PF08477.8 EGC33758.1 - 0.029 14.8 0.1 6.5 7.2 0.0 3.2 3 0 0 3 3 3 0 Miro-like protein SbcCD_C PF13558.1 EGC33758.1 - 0.059 13.2 0.0 0.39 10.6 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EGC33758.1 - 0.077 12.9 3.3 0.13 12.2 0.7 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGC33758.1 - 0.097 12.3 1.3 4.2 7.0 0.4 2.3 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EGC33758.1 - 0.11 12.1 0.8 0.95 9.1 0.1 2.4 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 PduV-EutP PF10662.4 EGC33758.1 - 0.11 12.0 1.9 1.3 8.5 0.3 2.4 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation ATP-synt_ab PF00006.20 EGC33758.1 - 0.17 11.3 0.2 3.7 6.9 0.1 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain AAA_19 PF13245.1 EGC33758.1 - 0.17 11.6 0.3 10 5.9 0.1 2.4 2 0 0 2 2 2 0 Part of AAA domain T2SE PF00437.15 EGC33758.1 - 0.49 9.2 0.1 18 4.1 0.0 2.4 2 1 0 2 2 2 0 Type II/IV secretion system protein AAA_30 PF13604.1 EGC33758.1 - 1.6 8.2 3.6 4.5 6.7 0.2 2.5 3 0 0 3 3 3 0 AAA domain Actin PF00022.14 EGC33759.1 - 3.5e-136 453.7 0.0 4e-136 453.5 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC33759.1 - 3.7e-09 35.6 0.0 3.5e-06 25.8 0.0 2.2 2 0 0 2 2 2 2 MreB/Mbl protein Tweety PF04906.8 EGC33760.1 - 3.9e-13 48.5 8.2 8.4e-10 37.6 0.9 2.3 1 1 1 2 2 2 2 Tweety MRAP PF15183.1 EGC33760.1 - 0.02 14.4 0.9 0.02 14.4 0.6 2.6 3 0 0 3 3 3 0 Melanocortin-2 receptor accessory protein family CRA PF06589.6 EGC33760.1 - 0.6 9.4 4.4 1.4 8.1 0.8 2.4 2 0 0 2 2 2 0 Circumsporozoite-related antigen (CRA) zf-CCCH_2 PF14608.1 EGC33760.1 - 1.4 9.0 3.3 0.72 9.9 0.4 1.9 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type Phage_tail_2 PF06199.6 EGC33761.1 - 0.086 12.9 0.0 0.19 11.7 0.0 1.5 2 0 0 2 2 2 0 Phage major tail protein 2 Mucin PF01456.12 EGC33762.1 - 0.34 10.6 15.7 1.4 8.6 11.2 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein MSA-2c PF12238.3 EGC33762.1 - 4.2 6.9 5.8 6.6 6.3 4.0 1.3 1 0 0 1 1 1 0 Merozoite surface antigen 2c SUR7 PF06687.7 EGC33763.1 - 0.0074 15.8 1.9 0.0091 15.5 1.3 1.1 1 0 0 1 1 1 1 SUR7/PalI family DUF3430 PF11912.3 EGC33763.1 - 0.037 13.8 13.2 0.33 10.7 9.1 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) Prenylcys_lyase PF07156.9 EGC33764.1 - 7.9e-60 202.6 4.3 1.1e-59 202.1 3.0 1.2 1 0 0 1 1 1 1 Prenylcysteine lyase NAD_binding_8 PF13450.1 EGC33764.1 - 2e-05 24.4 1.3 3.4e-05 23.7 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Shikimate_dh_N PF08501.6 EGC33764.1 - 0.0029 17.6 0.1 0.72 9.9 0.0 3.0 3 0 0 3 3 3 1 Shikimate dehydrogenase substrate binding domain Amino_oxidase PF01593.19 EGC33764.1 - 0.11 11.5 0.0 0.19 10.7 0.0 1.4 1 0 0 1 1 1 0 Flavin containing amine oxidoreductase Coiled PF05710.7 EGC33765.1 - 0.0016 18.8 14.4 0.0022 18.4 10.0 1.2 1 0 0 1 1 1 1 Coiled coil FtsX PF02687.16 EGC33767.1 - 7.9e-32 109.5 37.5 2.2e-19 69.4 8.7 4.8 4 1 0 5 5 5 2 FtsX-like permease family Radical_SAM PF04055.16 EGC33768.1 - 2.2e-37 128.7 0.2 6.7e-37 127.2 0.1 1.9 2 0 0 2 2 2 1 Radical SAM superfamily UPF0004 PF00919.15 EGC33768.1 - 2.2e-31 107.5 0.3 4.4e-31 106.6 0.2 1.5 1 0 0 1 1 1 1 Uncharacterized protein family UPF0004 TRAM PF01938.15 EGC33768.1 - 8.2e-08 31.9 0.2 1.8e-07 30.8 0.2 1.6 1 0 0 1 1 1 1 TRAM domain Fer4_12 PF13353.1 EGC33768.1 - 0.062 13.4 0.1 0.56 10.3 0.0 2.5 2 0 0 2 2 2 0 4Fe-4S single cluster domain tRNA_anti-codon PF01336.20 EGC33769.1 - 0.0072 16.1 0.1 0.52 10.1 0.0 3.2 3 0 0 3 3 3 1 OB-fold nucleic acid binding domain NYD-SP12_N PF15015.1 EGC33769.1 - 0.011 14.0 1.7 0.017 13.3 1.2 1.2 1 0 0 1 1 1 0 Spermatogenesis-associated, N-terminal Leo1 PF04004.8 EGC33770.1 - 2.3 7.8 11.5 0.5 10.0 4.1 2.0 2 0 0 2 2 2 0 Leo1-like protein OAD_gamma PF04277.8 EGC33770.1 - 2.5 8.5 6.0 0.21 11.9 0.7 1.9 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain CAP_N PF01213.14 EGC33771.1 - 0.0027 17.0 4.9 0.0027 17.0 3.4 1.9 2 0 0 2 2 2 1 Adenylate cyclase associated (CAP) N terminal Thioredoxin PF00085.15 EGC33772.1 - 6.7e-09 35.3 0.0 1.7e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin Methyltransf_12 PF08242.7 EGC33772.1 - 0.11 12.9 0.1 0.23 11.9 0.1 1.5 1 0 0 1 1 1 0 Methyltransferase domain TPR_12 PF13424.1 EGC33773.1 - 3.3e-30 103.8 0.8 8.8e-08 31.9 0.0 5.1 4 1 1 5 5 5 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGC33773.1 - 3e-09 36.0 6.2 1.5 8.9 0.0 7.6 8 0 0 8 8 8 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC33773.1 - 4.4e-08 32.3 20.9 0.64 9.9 0.0 8.2 8 1 0 8 8 8 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGC33773.1 - 1.1e-06 28.7 0.0 0.26 12.0 0.0 5.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC33773.1 - 3e-06 26.9 0.8 2 8.4 0.3 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC33773.1 - 3.2e-06 26.7 10.1 0.023 14.3 0.0 5.6 4 2 2 6 6 6 3 TPR repeat TPR_19 PF14559.1 EGC33773.1 - 3.2e-06 27.3 0.1 0.43 10.9 0.0 4.6 4 1 0 4 4 4 2 Tetratricopeptide repeat Apc5 PF12862.2 EGC33773.1 - 0.00017 21.3 1.6 1.2 8.9 0.0 3.8 2 1 2 4 4 4 2 Anaphase-promoting complex subunit 5 TPR_16 PF13432.1 EGC33773.1 - 0.0043 17.6 0.0 5.2 7.8 0.0 3.3 3 1 1 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC33773.1 - 0.094 12.5 1.4 52 3.9 0.0 4.7 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC33773.1 - 0.11 12.1 0.0 0.11 12.1 0.0 5.9 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC33773.1 - 0.11 12.9 0.3 1.6e+02 3.0 0.0 4.8 6 0 0 6 6 6 0 Tetratricopeptide repeat HSF_DNA-bind PF00447.12 EGC33774.1 - 0.56 10.3 8.0 0.29 11.3 0.7 2.9 2 1 1 3 3 3 0 HSF-type DNA-binding GRIP PF01465.15 EGC33775.1 - 0.05 13.1 0.6 0.092 12.2 0.1 1.7 2 0 0 2 2 2 0 GRIP domain Ribosomal_L34e PF01199.13 EGC33776.1 - 2e-38 130.4 4.1 2e-38 130.4 2.9 1.4 2 0 0 2 2 2 1 Ribosomal protein L34e Pox_A3L PF05288.6 EGC33776.1 - 0.046 13.4 0.2 0.97 9.2 0.1 2.2 2 0 0 2 2 2 0 Poxvirus A3L Protein SynMuv_product PF06047.6 EGC33776.1 - 0.14 11.8 2.3 1.2 8.8 1.6 2.0 1 1 0 1 1 1 0 Ras-induced vulval development antagonist UQ_con PF00179.21 EGC33777.1 - 5.9e-40 135.9 0.0 6.7e-40 135.7 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RRM_1 PF00076.17 EGC33778.1 - 4.8e-19 67.7 0.2 1.1e-18 66.5 0.0 1.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC33778.1 - 1.2e-13 50.6 0.1 3.6e-13 49.1 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC33778.1 - 7.4e-12 45.0 0.0 1.2e-11 44.3 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Asn_synthase PF00733.16 EGC33780.1 - 1.1e-55 188.9 0.0 1.7e-55 188.3 0.0 1.3 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC33780.1 - 2e-43 147.0 0.0 4.1e-43 146.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC33780.1 - 1.6e-34 118.7 0.0 3.1e-34 117.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGC33780.1 - 1.5e-05 24.3 0.0 5.2e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EGC33780.1 - 9.4e-05 21.2 0.0 0.094 11.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II DNA_pol_A_exo1 PF01612.15 EGC33781.1 - 7.8e-09 35.2 0.0 1.3e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 3'-5' exonuclease DUF2118 PF09891.4 EGC33781.1 - 0.37 10.4 3.6 0.78 9.4 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2118) Metallophos_2 PF12850.2 EGC33782.1 - 3.9e-18 65.7 0.0 6.6e-18 65.0 0.0 1.3 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGC33782.1 - 1.9e-15 56.8 1.6 3.2e-15 56.0 1.1 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_3 PF14582.1 EGC33782.1 - 7.4e-15 54.7 0.0 6.7e-13 48.3 0.0 2.8 1 1 0 1 1 1 1 Metallophosphoesterase, calcineurin superfamily DUF4121 PF13497.1 EGC33782.1 - 0.012 14.6 0.1 0.019 14.0 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4121) Kelch_4 PF13418.1 EGC33783.1 - 5.6e-44 147.6 10.2 5e-09 35.7 0.0 6.4 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC33783.1 - 7.1e-39 131.1 16.3 3.4e-08 33.4 0.1 6.8 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC33783.1 - 1.2e-29 101.7 9.8 9.1e-07 28.6 0.0 6.5 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC33783.1 - 3e-27 93.6 17.5 9.4e-06 25.5 0.0 6.5 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC33783.1 - 3.1e-27 93.2 12.1 7.3e-06 25.5 0.3 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EGC33783.1 - 3.9e-26 90.3 10.3 0.00063 19.2 0.2 6.5 6 0 0 6 6 6 6 Kelch motif SAM_2 PF07647.12 EGC33783.1 - 6.2e-10 38.7 0.3 1.3e-09 37.7 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC33783.1 - 1.6e-08 34.5 0.1 3e-08 33.7 0.1 1.4 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) Mucin PF01456.12 EGC33783.1 - 0.021 14.5 12.7 0.038 13.7 8.8 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein XPC-binding PF09280.6 EGC33784.1 - 2.3e-19 68.5 2.5 4.8e-19 67.5 1.7 1.5 1 0 0 1 1 1 1 XPC-binding domain UBA PF00627.26 EGC33784.1 - 1.1e-17 63.2 3.6 7.9e-10 38.2 0.1 2.5 2 0 0 2 2 2 2 UBA/TS-N domain ubiquitin PF00240.18 EGC33784.1 - 3.1e-17 61.7 0.3 7.2e-17 60.5 0.2 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC33784.1 - 9.1e-07 28.4 0.6 1.9e-06 27.4 0.4 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Rad60-SLD_2 PF13881.1 EGC33784.1 - 0.00052 19.8 0.0 0.0015 18.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA_3 PF09288.5 EGC33784.1 - 0.00084 18.8 0.1 0.009 15.5 0.0 2.4 2 0 0 2 2 2 1 Fungal ubiquitin-associated domain MCM_N PF14551.1 EGC33784.1 - 0.015 15.7 0.0 0.034 14.6 0.0 1.6 1 0 0 1 1 1 0 MCM N-terminal domain DUF2407 PF10302.4 EGC33784.1 - 0.026 14.7 0.4 0.057 13.6 0.3 1.8 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain MSA-2c PF12238.3 EGC33784.1 - 0.074 12.7 9.7 0.11 12.0 6.7 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c SOG2 PF10428.4 EGC33784.1 - 0.098 11.2 7.9 0.13 10.8 5.5 1.2 1 0 0 1 1 1 0 RAM signalling pathway protein DUF605 PF04652.11 EGC33784.1 - 1.4 8.2 14.7 2.2 7.5 10.2 1.2 1 0 0 1 1 1 0 Vta1 like Spc7_N PF15402.1 EGC33784.1 - 1.5 6.7 12.1 2.1 6.2 8.4 1.1 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PRCC PF10253.4 EGC33784.1 - 1.7 9.3 7.2 2.6 8.7 5.0 1.3 1 0 0 1 1 1 0 Mitotic checkpoint regulator, MAD2B-interacting Golgin_A5 PF09787.4 EGC33784.1 - 1.9 6.9 5.2 2.9 6.3 3.6 1.2 1 0 0 1 1 1 0 Golgin subfamily A member 5 Neisseria_TspB PF05616.8 EGC33784.1 - 2.9 6.1 17.8 4.4 5.5 12.3 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Med13_C PF06333.7 EGC33784.1 - 4.1 5.8 7.6 5.4 5.4 5.3 1.1 1 0 0 1 1 1 0 Mediator complex subunit 13 C-terminal DUF566 PF04484.7 EGC33784.1 - 8.3 5.8 7.1 11 5.3 4.9 1.1 1 0 0 1 1 1 0 Family of unknown function (DUF566) PhoPQ_related PF10142.4 EGC33785.1 - 2.2e-98 329.1 0.9 2.7e-98 328.8 0.6 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein DUF515 PF04415.7 EGC33785.1 - 0.0058 14.9 0.0 0.011 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF515) EF_TS PF00889.14 EGC33786.1 - 6.4e-39 133.5 0.3 1.4e-37 129.2 0.2 2.3 1 1 0 1 1 1 1 Elongation factor TS UBA PF00627.26 EGC33786.1 - 1e-07 31.5 0.0 2.9e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 UBA/TS-N domain HBS1_N PF08938.5 EGC33786.1 - 0.0031 17.5 2.2 0.0064 16.5 0.1 2.2 2 0 0 2 2 2 1 HBS1 N-terminus DUF1065 PF06358.6 EGC33786.1 - 0.0078 15.9 2.7 1.3 8.7 0.6 2.6 2 1 0 2 2 2 2 Protein of unknown function (DUF1065) UBA_4 PF14555.1 EGC33786.1 - 0.067 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 UBA-like domain RRM_1 PF00076.17 EGC33787.1 - 1.1e-33 114.6 0.0 1.7e-16 59.6 0.0 3.9 3 1 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC33787.1 - 1.5e-26 92.1 0.0 3.3e-12 46.1 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC33787.1 - 2.4e-13 49.6 0.1 0.00013 21.7 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGC33787.1 - 3.4e-06 25.8 18.9 4e-06 25.6 13.1 1.1 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Spo7_2_N PF15407.1 EGC33787.1 - 0.059 12.8 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 Sporulation protein family 7 NID PF07292.8 EGC33787.1 - 0.12 12.4 0.1 1 9.4 0.0 2.3 2 0 0 2 2 2 0 Nmi/IFP 35 domain (NID) Cupin_8 PF13621.1 EGC33788.1 - 3.8e-46 157.6 6.4 3.8e-46 157.6 4.4 1.8 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 EGC33788.1 - 2.6e-05 23.6 0.0 4.2e-05 22.9 0.0 1.4 1 0 0 1 1 1 1 Cupin superfamily protein P5CR_dimer PF14748.1 EGC33789.1 - 5.7e-27 93.8 0.4 9.8e-27 93.0 0.3 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGC33789.1 - 6.4e-17 61.7 0.1 1.5e-16 60.6 0.1 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_binding_2 PF03446.10 EGC33789.1 - 8e-07 29.0 0.0 2e-06 27.7 0.0 1.6 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase ApbA PF02558.11 EGC33789.1 - 1.9e-06 27.4 0.6 5.4e-06 25.9 0.2 1.9 2 1 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGC33789.1 - 4e-06 26.6 1.1 2e-05 24.3 0.7 2.0 1 1 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus IlvN PF07991.7 EGC33789.1 - 0.00032 20.1 0.2 0.00052 19.4 0.1 1.5 1 1 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain TrkA_N PF02254.13 EGC33789.1 - 0.0011 18.8 0.1 0.0029 17.5 0.0 1.8 1 1 0 1 1 1 1 TrkA-N domain Saccharop_dh PF03435.13 EGC33789.1 - 0.017 14.1 0.2 0.027 13.4 0.1 1.4 1 0 0 1 1 1 0 Saccharopine dehydrogenase PDH PF02153.12 EGC33789.1 - 0.079 11.8 0.2 0.14 11.0 0.1 1.4 1 0 0 1 1 1 0 Prephenate dehydrogenase V_ATPase_I PF01496.14 EGC33791.1 - 1.1 7.0 13.4 1.3 6.7 9.3 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Chisel PF15355.1 EGC33791.1 - 6.4 6.8 7.5 9.8 6.2 0.1 3.3 3 1 0 3 3 3 0 Stretch-responsive small skeletal muscle X protein, Chisel Isochorismatase PF00857.15 EGC33792.1 - 0.1 12.4 0.0 0.12 12.3 0.0 1.1 1 0 0 1 1 1 0 Isochorismatase family DUF1349 PF07081.6 EGC33793.1 - 0.063 12.6 0.1 14 5.0 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1349) Bud13 PF09736.4 EGC33793.1 - 0.41 10.8 3.0 18 5.6 0.0 3.1 4 0 0 4 4 4 0 Pre-mRNA-splicing factor of RES complex EGF_2 PF07974.8 EGC33797.1 - 0.95 9.6 17.0 0.16 12.2 8.9 1.9 2 0 0 2 2 2 0 EGF-like domain Rpr2 PF04032.11 EGC33799.1 - 3.6e-06 26.7 8.6 3.6e-06 26.7 6.0 2.6 1 1 1 2 2 2 1 RNAse P Rpr2/Rpp21/SNM1 subunit domain zf-ribbon_3 PF13248.1 EGC33799.1 - 0.041 13.0 0.9 0.41 9.9 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGC33799.1 - 0.69 9.7 4.6 7.9 6.3 3.2 2.3 1 1 0 1 1 1 0 Double zinc ribbon TSA PF03249.8 EGC33799.1 - 2 6.8 10.6 2.4 6.6 7.4 1.1 1 0 0 1 1 1 0 Type specific antigen Cwf_Cwc_15 PF04889.7 EGC33800.1 - 0.41 10.3 28.7 0.54 9.9 19.9 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein RTBV_P46 PF06216.6 EGC33800.1 - 0.7 8.6 16.3 0.33 9.7 2.7 2.1 1 1 1 2 2 2 0 Rice tungro bacilliform virus P46 protein Ax_dynein_light PF10211.4 EGC33800.1 - 1.6 8.5 37.4 0.93 9.3 8.8 2.2 2 0 0 2 2 2 0 Axonemal dynein light chain Herpes_BLRF2 PF05812.7 EGC33800.1 - 2.5 7.9 23.4 0.33 10.7 4.7 3.5 2 2 2 4 4 4 0 Herpesvirus BLRF2 protein DUF4194 PF13835.1 EGC33800.1 - 2.7 7.4 12.6 0.78 9.1 3.7 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4194) DUF972 PF06156.8 EGC33800.1 - 3.3 8.1 33.6 3.1 8.1 8.9 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF972) AAA_13 PF13166.1 EGC33800.1 - 6.1 5.1 34.5 22 3.3 24.0 1.6 1 1 0 1 1 1 0 AAA domain DUF3979 PF13141.1 EGC33801.1 - 0.28 11.0 0.0 0.28 11.0 0.0 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF3979) RabGAP-TBC PF00566.13 EGC33801.1 - 3.4 7.0 7.6 10 5.5 0.1 2.2 2 0 0 2 2 2 0 Rab-GTPase-TBC domain PDZ_1 PF12812.2 EGC33802.1 - 0.045 13.6 0.1 0.087 12.7 0.1 1.6 1 1 0 1 1 1 0 PDZ-like domain POP1 PF06978.6 EGC33802.1 - 1.7 8.2 18.3 2 8.0 12.7 1.2 1 0 0 1 1 1 0 Ribonucleases P/MRP protein subunit POP1 PA14 PF07691.7 EGC33803.1 - 4.9e-14 52.2 0.1 7.6e-14 51.5 0.0 1.3 1 0 0 1 1 1 1 PA14 domain DUF4326 PF14216.1 EGC33804.1 - 6.3e-23 81.1 0.1 1.4e-22 80.0 0.1 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4326) UQ_con PF00179.21 EGC33805.1 - 2e-36 124.5 0.0 3.1e-36 123.8 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Med3 PF11593.3 EGC33805.1 - 0.052 12.7 11.2 0.064 12.4 7.7 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Mucin PF01456.12 EGC33805.1 - 0.51 10.1 25.0 0.68 9.7 17.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein TFIIF_alpha PF05793.7 EGC33805.1 - 2.3 6.5 9.3 2.9 6.1 6.5 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) CAF-1_p150 PF11600.3 EGC33805.1 - 4.2 6.6 11.8 5.7 6.2 8.2 1.2 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal WD40 PF00400.27 EGC33807.1 - 3.6e-63 207.3 18.3 3.1e-11 42.7 0.0 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat Alpha_kinase PF02816.13 EGC33807.1 - 1.2e-59 201.2 0.4 1.2e-59 201.2 0.3 1.8 2 0 0 2 2 2 1 Alpha-kinase family Nup160 PF11715.3 EGC33807.1 - 1.7e-11 42.9 6.9 0.0018 16.4 0.2 5.2 2 1 3 5 5 5 5 Nucleoporin Nup120/160 PQQ_3 PF13570.1 EGC33807.1 - 0.00066 19.8 0.0 47 4.4 0.0 5.4 6 0 0 6 6 6 0 PQQ-like domain FNIP PF05725.7 EGC33808.1 - 5.7e-82 269.4 32.1 7.8e-16 57.7 0.2 7.6 3 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC33808.1 - 2.4e-06 27.3 9.4 0.62 10.0 0.1 7.7 3 2 6 9 9 9 3 Protein of unknown function (DUF1769) Med15 PF09606.5 EGC33809.1 - 0.6 8.2 29.9 0.81 7.8 20.8 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PA14 PF07691.7 EGC33811.1 - 5e-16 58.6 0.1 7.8e-16 58.0 0.1 1.3 1 0 0 1 1 1 1 PA14 domain CYTH PF01928.16 EGC33813.1 - 0.12 12.0 0.1 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 CYTH domain FNIP PF05725.7 EGC33814.1 - 4.5e-66 218.5 28.6 2.8e-14 52.7 0.5 7.0 3 1 4 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC33814.1 - 0.0049 16.7 13.9 19 5.2 0.0 7.3 6 2 4 10 10 10 3 Protein of unknown function (DUF1769) Mis12 PF05859.7 EGC33815.1 - 1.5e-17 63.7 0.1 1.5e-17 63.7 0.1 2.8 3 0 0 3 3 3 1 Mis12 protein Reo_sigmaC PF04582.7 EGC33815.1 - 0.24 10.5 11.0 0.35 10.0 7.6 1.2 1 0 0 1 1 1 0 Reovirus sigma C capsid protein DIT1_PvcA PF05141.7 EGC33815.1 - 1.6 7.9 14.9 0.011 15.0 4.6 1.6 2 0 0 2 2 2 0 Pyoverdine/dityrosine biosynthesis protein Pkinase PF00069.20 EGC33816.1 - 4.2e-76 255.5 0.0 5e-76 255.2 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33816.1 - 3.7e-41 140.9 0.0 5e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC33816.1 - 2.5e-05 23.3 0.0 4.3e-05 22.6 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC33816.1 - 0.022 13.8 0.0 0.034 13.1 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family PH_3 PF14593.1 EGC33817.1 - 5.3e-29 100.1 0.8 9.6e-29 99.3 0.1 1.7 2 0 0 2 2 2 1 PH domain Herpes_LMP2 PF07415.6 EGC33817.1 - 0.15 10.6 0.6 0.2 10.1 0.4 1.1 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein Gtr1_RagA PF04670.7 EGC33819.1 - 1.3e-73 246.9 3.9 1.7e-73 246.5 2.7 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Arf PF00025.16 EGC33819.1 - 3.9e-07 29.4 0.0 7e-07 28.6 0.0 1.4 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC33819.1 - 7e-07 29.7 0.1 1.4e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC33819.1 - 1.5e-05 24.8 0.1 0.00011 22.1 0.0 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC33819.1 - 7.1e-05 22.1 0.0 0.00012 21.3 0.0 1.4 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC33819.1 - 0.00024 20.5 0.2 0.00034 20.0 0.1 1.2 1 0 0 1 1 1 1 Ras family Stirrup PF09061.1 EGC33819.1 - 0.0031 17.3 0.1 1.2 9.0 0.0 2.4 2 0 0 2 2 2 2 Stirrup AAA_14 PF13173.1 EGC33819.1 - 0.053 13.4 0.1 0.11 12.3 0.1 1.7 1 1 0 1 1 1 0 AAA domain Pkinase PF00069.20 EGC33820.1 - 4.2e-24 85.1 0.9 9.2e-24 83.9 0.6 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC33820.1 - 2.9e-13 49.4 0.1 4.9e-13 48.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase TRM PF02005.11 EGC33821.1 - 3.6e-125 417.7 1.8 5.2e-125 417.2 1.3 1.2 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase Amino_oxidase PF01593.19 EGC33822.1 - 1.7e-35 122.9 0.0 6.2e-26 91.4 0.0 2.1 2 0 0 2 2 2 2 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC33822.1 - 3.2e-10 39.8 0.0 7.9e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGC33822.1 - 3.9e-05 22.8 0.3 8.3e-05 21.8 0.1 1.5 2 0 0 2 2 2 1 FAD binding domain Pyr_redox_3 PF13738.1 EGC33822.1 - 0.00092 19.3 0.0 0.0066 16.5 0.0 2.2 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase AlaDh_PNT_C PF01262.16 EGC33822.1 - 0.054 13.0 0.0 0.15 11.6 0.0 1.7 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain HI0933_like PF03486.9 EGC33822.1 - 0.11 10.9 0.1 0.19 10.1 0.1 1.3 1 0 0 1 1 1 0 HI0933-like protein FAD_binding_2 PF00890.19 EGC33822.1 - 0.17 10.7 0.2 0.28 10.0 0.1 1.3 1 0 0 1 1 1 0 FAD binding domain Amino_oxidase PF01593.19 EGC33823.1 - 3.5e-43 148.3 0.0 1.1e-30 107.1 0.0 3.1 3 0 0 3 3 3 2 Flavin containing amine oxidoreductase DAO PF01266.19 EGC33823.1 - 3.5e-32 111.6 0.0 2.6e-29 102.2 0.0 3.0 2 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGC33823.1 - 4.5e-18 65.0 0.1 2.4e-09 37.1 0.0 2.8 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain FAD_binding_3 PF01494.14 EGC33823.1 - 2.6e-10 39.8 0.9 0.00048 19.2 0.0 2.5 2 0 0 2 2 2 2 FAD binding domain FAD_binding_2 PF00890.19 EGC33823.1 - 6e-10 38.5 0.8 4.3e-07 29.1 0.1 2.3 2 0 0 2 2 2 2 FAD binding domain Thi4 PF01946.12 EGC33823.1 - 1e-09 37.8 0.2 4.4e-07 29.2 0.0 2.3 2 0 0 2 2 2 2 Thi4 family HI0933_like PF03486.9 EGC33823.1 - 2e-08 33.1 0.9 2.3e-05 23.0 0.0 2.4 2 0 0 2 2 2 2 HI0933-like protein Pyr_redox_3 PF13738.1 EGC33823.1 - 9.4e-08 32.3 0.0 0.016 15.2 0.0 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC33823.1 - 2.2e-07 30.9 0.1 0.00015 21.6 0.1 2.5 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC33823.1 - 1.2e-06 28.8 3.7 0.0015 18.8 0.1 2.9 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC33823.1 - 1.7e-06 27.3 0.4 4.3e-06 26.0 0.0 1.7 2 0 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGC33823.1 - 4.7e-06 25.7 0.3 0.0022 16.9 0.0 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A NAD_binding_7 PF13241.1 EGC33823.1 - 0.0032 17.6 0.0 0.0071 16.5 0.0 1.5 1 0 0 1 1 1 1 Putative NAD(P)-binding AlaDh_PNT_C PF01262.16 EGC33823.1 - 0.006 16.1 0.1 0.71 9.4 0.0 2.5 2 0 0 2 2 2 1 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGC33823.1 - 0.0074 15.9 1.0 0.19 11.3 0.0 2.3 2 0 0 2 2 2 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Lycopene_cycl PF05834.7 EGC33823.1 - 0.011 14.6 0.1 0.072 12.0 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein DHquinase_II PF01220.14 EGC33823.1 - 0.076 12.3 0.0 0.21 10.9 0.0 1.7 1 0 0 1 1 1 0 Dehydroquinase class II Trp_halogenase PF04820.9 EGC33823.1 - 0.16 10.5 1.5 0.61 8.6 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase K_oxygenase PF13434.1 EGC33823.1 - 0.18 10.6 0.0 7.7 5.3 0.0 2.4 2 0 0 2 2 2 0 L-lysine 6-monooxygenase (NADPH-requiring) FNIP PF05725.7 EGC33824.1 - 6e-77 253.3 35.4 9.1e-16 57.5 1.7 7.9 3 1 6 10 10 10 10 FNIP Repeat E3_UbLigase_R4 PF13764.1 EGC33825.1 - 1.9e-297 988.5 0.2 1.9e-297 988.5 0.1 3.1 2 0 0 2 2 2 1 E3 ubiquitin-protein ligase UBR4 ZZ PF00569.12 EGC33825.1 - 1.6e-10 40.3 6.9 1.6e-10 40.3 4.8 3.8 3 0 0 3 3 3 2 Zinc finger, ZZ type Spindle_Spc25 PF08234.7 EGC33826.1 - 5.7e-21 74.3 1.3 5.7e-21 74.3 0.9 2.4 2 0 0 2 2 2 1 Chromosome segregation protein Spc25 adh_short PF00106.20 EGC33827.1 - 2.9e-30 105.3 0.6 5.1e-30 104.5 0.4 1.3 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC33827.1 - 8.5e-26 91.1 0.0 1e-25 90.9 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC33827.1 - 1.8e-11 44.0 0.6 3.1e-11 43.2 0.1 1.6 2 1 0 2 2 2 1 KR domain FH2 PF02181.18 EGC33828.1 - 6.8e-85 285.1 14.9 6.8e-85 285.1 10.3 2.7 3 0 0 3 3 3 2 Formin Homology 2 Domain Mito_fiss_reg PF05308.6 EGC33828.1 - 7.7 5.7 15.9 0.25 10.6 6.0 2.2 2 0 0 2 2 2 0 Mitochondrial fission regulator Solute_trans_a PF03619.11 EGC33829.1 - 3.2e-59 200.4 23.1 1.2e-50 172.3 11.3 2.5 1 1 1 2 2 2 2 Organic solute transporter Ostalpha BRCT PF00533.21 EGC33830.1 - 8e-09 35.5 2.2 1.9e-08 34.3 1.6 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC33830.1 - 0.00029 20.6 0.3 0.00078 19.2 0.0 1.7 2 0 0 2 2 2 1 twin BRCT domain Glycos_transf_1 PF00534.15 EGC33831.1 - 2.8e-25 88.7 0.2 6.4e-25 87.5 0.1 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.21 EGC33831.1 - 7.2e-23 81.1 0.1 7.2e-23 81.1 0.1 3.2 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_trans_1_4 PF13692.1 EGC33831.1 - 1.1e-12 48.2 0.0 2.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.1 EGC33831.1 - 5e-09 36.2 0.0 1.6e-08 34.6 0.0 1.8 1 1 0 1 1 1 1 Glycosyltransferase like family 2 HALZ PF02183.13 EGC33831.1 - 0.025 14.2 4.0 0.38 10.5 0.3 2.7 2 0 0 2 2 2 0 Homeobox associated leucine zipper FtsH_ext PF06480.10 EGC33831.1 - 0.038 14.1 4.0 0.16 12.1 2.7 2.0 1 0 0 1 1 1 0 FtsH Extracellular Glyco_trans_1_2 PF13524.1 EGC33831.1 - 0.08 13.2 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 Glycosyl transferases group 1 Tetraspannin PF00335.15 EGC33831.1 - 1.3 8.2 10.5 3.7 6.7 7.3 1.7 1 0 0 1 1 1 0 Tetraspanin family HCO3_cotransp PF00955.16 EGC33831.1 - 2.2 6.8 5.2 3.9 6.0 3.6 1.3 1 0 0 1 1 1 0 HCO3- transporter family Shadoo PF14999.1 EGC33832.1 - 0.0043 16.9 3.9 0.007 16.2 2.7 1.3 1 0 0 1 1 1 1 Shadow of prion protein, neuroprotective PAT1 PF09770.4 EGC33832.1 - 1.2 7.3 60.3 1.7 6.7 41.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGC33832.1 - 5.4 5.0 63.4 7.7 4.5 44.0 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal PfkB PF00294.19 EGC33833.1 - 3.8e-10 39.3 0.3 1.1e-08 34.5 0.0 2.7 2 1 0 3 3 3 1 pfkB family carbohydrate kinase Dpoe2NT PF12213.3 EGC33833.1 - 0.098 12.5 0.2 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 DNA polymerases epsilon N terminal zf-B_box PF00643.19 EGC33834.1 - 0.011 15.5 7.2 0.024 14.5 5.0 1.6 1 0 0 1 1 1 0 B-box zinc finger CENP-Q PF13094.1 EGC33835.1 - 0.017 15.1 5.8 0.017 15.1 4.0 2.1 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF3958 PF13125.1 EGC33835.1 - 0.023 14.5 7.2 0.023 14.5 5.0 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF3958) DUF4041 PF13250.1 EGC33835.1 - 0.024 14.1 2.1 0.14 11.7 0.1 2.9 2 2 1 3 3 3 0 Domain of unknown function (DUF4041) GAS PF13851.1 EGC33835.1 - 0.035 13.2 38.1 0.13 11.4 7.5 2.4 1 1 0 2 2 2 0 Growth-arrest specific micro-tubule binding Sec8_exocyst PF04048.9 EGC33835.1 - 0.091 12.4 17.2 0.018 14.7 5.0 2.4 2 0 0 2 2 2 0 Sec8 exocyst complex component specific domain CENP-F_leu_zip PF10473.4 EGC33835.1 - 0.15 11.8 36.5 0.65 9.8 11.3 2.1 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Filament PF00038.16 EGC33835.1 - 0.17 11.3 32.1 1.7 8.0 22.3 2.6 1 1 0 1 1 1 0 Intermediate filament protein Reo_sigmaC PF04582.7 EGC33835.1 - 0.22 10.6 7.5 0.99 8.5 1.4 2.1 1 1 1 2 2 2 0 Reovirus sigma C capsid protein WEMBL PF05701.6 EGC33835.1 - 1 7.7 30.5 5.2 5.4 11.1 2.1 1 1 1 2 2 2 0 Weak chloroplast movement under blue light IncA PF04156.9 EGC33835.1 - 1.9 8.0 36.6 0.93 9.0 12.5 2.6 1 1 1 2 2 1 0 IncA protein Rad21_Rec8_N PF04825.8 EGC33835.1 - 1.9 8.4 6.4 0.87 9.5 2.0 2.4 1 1 1 2 2 2 0 N terminus of Rad21 / Rec8 like protein DUF1515 PF07439.6 EGC33835.1 - 2.1 8.2 7.1 11 5.9 0.0 3.2 1 1 3 4 4 4 0 Protein of unknown function (DUF1515) TPR_MLP1_2 PF07926.7 EGC33835.1 - 2.1 8.0 37.7 0.074 12.8 13.8 2.6 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Spc7 PF08317.6 EGC33835.1 - 3.1 6.3 34.6 0.013 14.1 12.1 2.1 1 1 1 2 2 2 0 Spc7 kinetochore protein Macoilin PF09726.4 EGC33835.1 - 4.7 5.3 27.7 7.7 4.6 19.2 1.3 1 1 0 1 1 1 0 Transmembrane protein DUF2937 PF11157.3 EGC33835.1 - 5 6.4 6.7 13 5.0 4.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2937) DUF724 PF05266.9 EGC33835.1 - 6 6.4 34.2 2.2 7.8 8.7 2.9 1 1 2 3 3 3 0 Protein of unknown function (DUF724) EF1G PF00647.14 EGC33836.1 - 3.4e-38 129.6 0.0 6e-38 128.8 0.0 1.4 1 0 0 1 1 1 1 Elongation factor 1 gamma, conserved domain GST_C PF00043.20 EGC33836.1 - 4e-09 36.3 2.4 6.7e-09 35.6 0.0 2.2 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC33836.1 - 0.0011 19.3 0.0 0.0077 16.6 0.0 2.1 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC33836.1 - 0.0012 18.6 0.0 0.0023 17.7 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain TIG PF01833.19 EGC33837.1 - 9.4e-22 76.8 17.7 1.5e-12 47.2 2.7 4.0 4 1 0 4 4 4 2 IPT/TIG domain FNIP PF05725.7 EGC33838.1 - 3.7e-57 190.0 69.6 1.2e-14 53.9 0.5 7.7 2 2 6 8 8 8 8 FNIP Repeat LRR_7 PF13504.1 EGC33838.1 - 0.0033 17.3 5.8 42 4.9 0.0 6.4 7 1 0 7 7 7 2 Leucine rich repeat Peptidase_S28 PF05577.7 EGC33840.1 - 5.9e-52 176.7 0.3 7.9e-52 176.2 0.2 1.1 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Ribosomal_S9 PF00380.14 EGC33841.1 - 8e-34 116.4 0.1 1.4e-33 115.6 0.1 1.4 1 0 0 1 1 1 1 Ribosomal protein S9/S16 Cu-oxidase_4 PF02578.10 EGC33841.1 - 0.16 11.0 0.1 0.23 10.4 0.0 1.2 1 0 0 1 1 1 0 Multi-copper polyphenol oxidoreductase laccase UPF0370 PF13980.1 EGC33842.1 - 0.038 13.7 0.0 0.045 13.5 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0370) V-SNARE PF05008.10 EGC33843.1 - 1.7e-14 53.6 4.2 1.7e-14 53.6 2.9 2.7 3 0 0 3 3 3 1 Vesicle transport v-SNARE protein N-terminus V-SNARE_C PF12352.3 EGC33843.1 - 1.8e-10 40.6 5.8 1.8e-10 40.6 4.0 3.3 2 2 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGC33843.1 - 2.6e-05 23.8 0.4 2.6e-05 23.8 0.3 2.3 2 0 0 2 2 2 1 Sec20 DUF4407 PF14362.1 EGC33843.1 - 0.00034 19.6 2.0 0.0004 19.4 1.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4407) WEMBL PF05701.6 EGC33843.1 - 0.004 15.6 4.0 0.0051 15.3 2.8 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light Fusion_gly PF00523.13 EGC33843.1 - 0.014 13.4 1.4 0.016 13.2 0.2 1.6 1 1 0 1 1 1 0 Fusion glycoprotein F0 Ribosomal_S20p PF01649.13 EGC33843.1 - 0.023 15.0 4.2 1.4 9.3 1.2 2.4 2 0 0 2 2 2 0 Ribosomal protein S20 DSX_dimer PF08828.5 EGC33843.1 - 0.028 13.9 0.6 0.11 12.0 0.4 2.0 1 0 0 1 1 1 0 Doublesex dimerisation domain DUF3596 PF12167.3 EGC33843.1 - 0.063 12.8 0.8 0.2 11.1 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3596) DUF4110 PF13422.1 EGC33843.1 - 0.081 12.7 2.0 0.17 11.7 1.4 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4110) Maelstrom PF13017.1 EGC33843.1 - 0.1 12.1 1.1 0.24 10.8 0.2 1.8 2 0 0 2 2 2 0 piRNA pathway germ-plasm component Phage_GPO PF05929.6 EGC33843.1 - 0.11 11.7 11.1 0.026 13.7 0.9 2.1 1 1 1 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase Laminin_II PF06009.7 EGC33843.1 - 0.12 12.1 9.0 1.5 8.5 0.1 2.4 2 0 0 2 2 2 0 Laminin Domain II DUF939_C PF11728.3 EGC33843.1 - 0.17 11.6 10.0 0.45 10.3 4.9 2.4 1 1 1 2 2 2 0 DUF939 C-terminal domain PspA_IM30 PF04012.7 EGC33843.1 - 0.23 10.7 7.8 1.4 8.2 5.4 2.0 1 1 0 1 1 1 0 PspA/IM30 family Mnd1 PF03962.10 EGC33843.1 - 0.23 11.0 9.5 0.048 13.3 2.8 2.2 2 0 0 2 2 2 0 Mnd1 family CENP-H PF05837.7 EGC33843.1 - 0.73 10.0 12.1 0.7 10.1 2.5 2.3 2 0 0 2 2 2 0 Centromere protein H (CENP-H) SNARE PF05739.14 EGC33843.1 - 1.3 8.8 12.3 0.072 12.7 2.5 3.1 3 2 0 3 3 3 0 SNARE domain DASH_Spc34 PF08657.5 EGC33843.1 - 1.4 8.5 10.2 0.98 9.0 5.8 1.8 1 1 1 2 2 2 0 DASH complex subunit Spc34 E2R135 PF11570.3 EGC33843.1 - 1.9 8.6 6.3 1.4 9.0 2.2 2.0 1 1 1 2 2 2 0 Coiled-coil receptor-binding R-domain of colicin E2 Rootletin PF15035.1 EGC33843.1 - 2 8.3 14.3 2.2 8.2 8.5 2.1 1 1 0 1 1 1 0 Ciliary rootlet component, centrosome cohesion DUF16 PF01519.11 EGC33843.1 - 3.3 7.9 13.1 7.7e+02 0.3 9.1 2.2 1 1 0 1 1 1 0 Protein of unknown function DUF16 Spectrin PF00435.16 EGC33843.1 - 4.1 7.7 10.6 1.5 9.1 2.5 3.0 2 1 1 3 3 3 0 Spectrin repeat Strep_SA_rep PF06696.6 EGC33843.1 - 4.6 7.1 7.3 11 5.8 5.1 1.7 1 0 0 1 1 1 0 Streptococcal surface antigen repeat DUF1090 PF06476.7 EGC33843.1 - 8.2 6.1 10.6 1.3 8.6 2.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF1090) G8 PF10162.4 EGC33844.1 - 5.3e-29 100.5 0.4 5.3e-29 100.5 0.3 2.2 2 0 0 2 2 2 1 G8 domain Fibrinogen_aC PF12160.3 EGC33845.1 - 0.021 14.2 1.8 0.038 13.4 1.3 1.3 1 0 0 1 1 1 0 Fibrinogen alpha C domain ubiquitin PF00240.18 EGC33846.1 - 3.2e-13 48.8 0.1 5e-13 48.2 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC33846.1 - 2.5e-07 30.3 0.1 4.4e-07 29.4 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3990 PF13151.1 EGC33846.1 - 0.01 15.1 0.1 0.02 14.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3990) CTDII PF01556.13 EGC33846.1 - 0.1 12.4 0.1 0.22 11.4 0.1 1.6 1 0 0 1 1 1 0 DnaJ C terminal domain AA_permease_2 PF13520.1 EGC33847.1 - 5.6e-49 166.8 47.0 7.1e-49 166.4 32.6 1.1 1 0 0 1 1 1 1 Amino acid permease DSPc PF00782.15 EGC33848.1 - 9e-27 93.2 0.8 1e-22 80.1 0.0 3.1 2 1 1 3 3 3 2 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGC33848.1 - 2e-10 40.8 1.0 2e-10 40.8 0.7 3.2 2 1 1 3 3 3 1 Inositol hexakisphosphate Y_phosphatase2 PF03162.8 EGC33848.1 - 5.2e-05 22.6 4.2 0.00093 18.5 0.1 3.5 3 1 1 4 4 4 1 Tyrosine phosphatase family PASTA PF03793.14 EGC33848.1 - 0.024 14.2 3.4 0.12 11.9 1.5 2.6 2 0 0 2 2 2 0 PASTA domain Mucin PF01456.12 EGC33848.1 - 0.3 10.8 21.2 1.3 8.7 8.6 2.2 2 0 0 2 2 2 0 Mucin-like glycoprotein SIR2_2 PF13289.1 EGC33849.1 - 8.1e-27 93.8 0.2 4.7e-26 91.3 0.1 2.4 1 0 0 1 1 1 1 SIR2-like domain Pyridoxal_deC PF00282.14 EGC33850.1 - 3.3e-17 62.0 0.0 3.9e-13 48.5 0.0 3.2 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain SR-25 PF10500.4 EGC33851.1 - 0.0062 16.0 7.0 0.0067 15.9 4.8 1.1 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Tom37_C PF11801.3 EGC33851.1 - 0.25 11.2 2.5 0.27 11.0 1.7 1.1 1 0 0 1 1 1 0 Tom37 C-terminal domain YolD PF08863.5 EGC33853.1 - 3.9 7.4 9.6 0.93 9.3 1.1 3.0 2 2 1 3 3 3 0 YolD-like protein DUF2803 PF10972.3 EGC33855.1 - 0.012 15.0 0.6 0.019 14.4 0.4 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2803) MCM PF00493.18 EGC33856.1 - 4e-97 324.9 0.4 5.6e-97 324.4 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EGC33856.1 - 1.6e-06 27.4 0.0 0.00022 20.4 0.0 2.6 1 1 2 3 3 3 1 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC33856.1 - 1.2e-05 25.0 0.0 2.9e-05 23.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA PF00004.24 EGC33856.1 - 0.00048 20.3 0.0 0.0012 19.0 0.0 1.8 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGC33856.1 - 0.014 14.8 0.0 0.032 13.7 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_3 PF07726.6 EGC33856.1 - 0.021 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF2625 PF10946.3 EGC33856.1 - 0.069 12.0 0.0 0.16 10.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function DUF2625 dUTPase PF00692.14 EGC33857.1 - 8.1e-34 115.8 0.1 9.1e-34 115.7 0.0 1.0 1 0 0 1 1 1 1 dUTPase chaperone_DMP PF10448.4 EGC33857.1 - 0.025 14.4 0.0 0.032 14.1 0.0 1.2 1 0 0 1 1 1 0 20S proteasome chaperone zf-B_box PF00643.19 EGC33858.1 - 3.6e-11 42.7 20.4 1.7e-06 27.7 4.7 2.3 2 0 0 2 2 2 2 B-box zinc finger Sld5 PF05916.6 EGC33858.1 - 2.3e-05 24.6 0.1 4.7e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 GINS complex protein IBR PF01485.16 EGC33858.1 - 0.12 12.2 16.1 0.82 9.5 4.1 2.6 2 1 0 2 2 2 0 IBR domain E7 PF00527.13 EGC33858.1 - 0.21 11.7 11.7 1.9 8.7 2.5 2.4 1 1 1 2 2 2 0 E7 protein, Early protein Fer4_2 PF12797.2 EGC33858.1 - 1.4 8.9 10.2 6.9 6.8 1.2 2.6 2 0 0 2 2 2 0 4Fe-4S binding domain ZZ PF00569.12 EGC33858.1 - 2.3 7.8 16.0 0.63 9.6 0.7 3.6 1 1 2 3 3 3 0 Zinc finger, ZZ type Fer2 PF00111.22 EGC33858.1 - 2.7 7.7 8.9 7 6.4 1.4 2.3 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain DHODB_Fe-S_bind PF10418.4 EGC33858.1 - 3.1 7.3 6.4 1.6 8.3 0.2 2.3 2 0 0 2 2 2 0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B FNIP PF05725.7 EGC33859.1 - 1.8e-71 235.8 70.7 5.5e-18 64.6 2.5 8.9 5 3 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC33859.1 - 2e-08 34.0 15.1 7.6 6.5 0.0 8.5 4 2 4 8 8 8 7 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC33860.1 - 1.3e-33 114.6 14.6 6.7e-17 61.1 0.1 4.9 1 1 2 4 4 4 4 FNIP Repeat DUF1769 PF08588.5 EGC33860.1 - 7.2e-05 22.6 4.2 7.2 6.6 0.0 4.4 1 1 3 4 4 4 4 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC33861.1 - 1.9e-119 389.4 89.0 1.2e-15 57.1 0.1 14.6 7 4 6 15 15 15 14 FNIP Repeat Histone PF00125.19 EGC33862.1 - 5.1e-24 84.1 0.3 7.4e-24 83.6 0.2 1.3 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC33862.1 - 1.2e-05 25.3 0.1 1.8e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S CBFD_NFYB_HMF PF00808.18 EGC33862.1 - 0.0026 17.7 0.4 0.0042 17.1 0.3 1.4 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC33862.1 - 0.0052 16.4 0.1 0.0079 15.9 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated CENP-T PF15511.1 EGC33862.1 - 0.0065 15.7 0.1 0.0065 15.7 0.1 1.2 1 1 0 1 1 1 1 Centromere kinetochore component CENP-T TFIID-31kDa PF02291.10 EGC33862.1 - 0.028 14.2 0.0 0.044 13.5 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit TAF PF02969.12 EGC33862.1 - 0.094 12.6 0.2 0.17 11.8 0.1 1.4 1 0 0 1 1 1 0 TATA box binding protein associated factor (TAF) MRP-S28 PF10213.4 EGC33862.1 - 0.11 12.5 0.1 0.16 12.0 0.1 1.3 1 1 0 1 1 1 0 Mitochondrial ribosomal subunit protein FNIP PF05725.7 EGC33863.1 - 1.6e-34 117.5 32.1 7.6e-10 38.5 0.4 5.0 4 1 0 5 5 5 4 FNIP Repeat DUF1769 PF08588.5 EGC33863.1 - 4.2e-05 23.3 3.5 0.18 11.8 0.0 4.8 5 2 1 6 6 6 2 Protein of unknown function (DUF1769) uDENN PF03456.13 EGC33863.1 - 0.0075 16.2 0.3 4.5 7.3 0.0 2.7 2 0 0 2 2 2 2 uDENN domain Ribosomal_L11_N PF03946.9 EGC33863.1 - 0.22 11.0 3.1 27 4.2 0.0 3.8 2 2 2 4 4 4 0 Ribosomal protein L11, N-terminal domain Thioredoxin PF00085.15 EGC33864.1 - 7.1e-21 73.8 0.0 8.8e-21 73.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_9 PF14595.1 EGC33864.1 - 2e-07 30.6 0.0 2.3e-07 30.4 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGC33864.1 - 3e-05 24.0 0.0 0.00011 22.1 0.0 1.8 1 1 1 2 2 2 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC33864.1 - 0.0033 17.6 0.1 0.053 13.7 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Redoxin PF08534.5 EGC33864.1 - 0.017 14.6 0.0 0.023 14.2 0.0 1.2 1 0 0 1 1 1 0 Redoxin Thioredoxin_7 PF13899.1 EGC33864.1 - 0.023 14.7 0.0 0.035 14.1 0.0 1.4 1 1 0 1 1 1 0 Thioredoxin-like AhpC-TSA PF00578.16 EGC33864.1 - 0.043 13.5 0.0 0.044 13.4 0.0 1.2 1 0 0 1 1 1 0 AhpC/TSA family Phlebovirus_G2 PF07245.6 EGC33865.1 - 0.02 13.2 0.1 0.027 12.7 0.0 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G2 FNIP PF05725.7 EGC33866.1 - 1.9e-38 130.1 19.9 1e-14 54.1 0.1 5.4 4 1 0 6 6 6 3 FNIP Repeat DUF1769 PF08588.5 EGC33866.1 - 0.00041 20.2 7.1 7.4 6.6 0.0 5.0 2 1 4 6 6 6 3 Protein of unknown function (DUF1769) GAD PF02938.9 EGC33868.1 - 0.062 13.4 2.0 0.1 12.7 1.4 1.3 1 0 0 1 1 1 0 GAD domain Fib_alpha PF08702.5 EGC33869.1 - 0.54 10.3 4.5 0.74 9.9 3.1 1.2 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family DUF4284 PF14112.1 EGC33869.1 - 5.9 7.3 11.9 5 7.6 6.6 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF4284) MCM PF00493.18 EGC33871.1 - 4.6e-21 74.9 0.5 5e-21 74.8 0.4 1.0 1 0 0 1 1 1 1 MCM2/3/5 family DUF2660 PF10859.3 EGC33871.1 - 0.11 12.6 0.8 0.15 12.3 0.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2660) DUF2683 PF10884.3 EGC33871.1 - 0.32 10.9 4.2 0.31 10.9 0.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF2683) MCM PF00493.18 EGC33872.1 - 4.1e-54 183.6 3.1 5.7e-53 179.8 2.1 1.9 1 1 0 1 1 1 1 MCM2/3/5 family Mg_chelatase PF01078.16 EGC33872.1 - 1.2e-08 34.4 0.0 1.8e-07 30.5 0.0 2.1 1 1 1 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGC33872.1 - 0.015 14.9 0.0 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC33872.1 - 0.037 13.7 0.0 0.071 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) RuvB_N PF05496.7 EGC33872.1 - 0.068 12.2 0.0 0.12 11.3 0.0 1.4 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus Sigma54_activat PF00158.21 EGC33872.1 - 0.08 12.4 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain DUF3861 PF12977.2 EGC33873.1 - 0.0068 16.4 0.0 0.008 16.2 0.0 1.2 1 0 0 1 1 1 1 Domain of Unknown Function with PDB structure (DUF3861) DUF3330 PF11809.3 EGC33873.1 - 0.088 12.6 0.0 0.13 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3330) FNIP PF05725.7 EGC33874.1 - 1.7e-18 66.2 15.7 1.1e-10 41.2 1.8 3.2 2 1 1 3 3 3 2 FNIP Repeat DUF1413 PF07205.6 EGC33874.1 - 0.023 14.2 0.0 0.13 11.8 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1413) FerB PF08150.7 EGC33874.1 - 0.16 12.0 0.5 21 5.2 0.0 2.3 2 0 0 2 2 2 0 FerB (NUC096) domain Sld5 PF05916.6 EGC33875.1 - 5.1e-18 65.3 0.2 6.5e-18 65.0 0.2 1.1 1 0 0 1 1 1 1 GINS complex protein EF-1_beta_acid PF10587.4 EGC33876.1 - 1.9 8.7 0.0 1.9 8.7 0.0 3.3 4 0 0 4 4 4 0 Eukaryotic elongation factor 1 beta central acidic region Macoilin PF09726.4 EGC33876.1 - 2.2 6.4 23.2 2.7 6.1 16.1 1.0 1 0 0 1 1 1 0 Transmembrane protein PIF1 PF05970.9 EGC33876.1 - 2.6 6.9 6.1 3.5 6.4 4.2 1.3 1 0 0 1 1 1 0 PIF1-like helicase FNIP PF05725.7 EGC33877.1 - 8.6e-93 304.0 68.7 1.6e-16 59.9 0.9 7.7 4 2 5 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC33877.1 - 0.0063 16.4 18.3 18 5.3 0.0 8.3 5 5 5 10 10 10 3 Protein of unknown function (DUF1769) Thymidylate_kin PF02223.12 EGC33878.1 - 1.6e-35 122.2 0.0 2.5e-34 118.3 0.0 1.9 1 1 1 2 2 2 1 Thymidylate kinase AAA_28 PF13521.1 EGC33878.1 - 0.032 14.1 0.0 0.045 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Rad60-SLD PF11976.3 EGC33878.1 - 0.05 13.2 0.2 10 5.9 0.0 2.7 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like AAA_16 PF13191.1 EGC33878.1 - 0.078 12.9 0.0 0.099 12.6 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain RNA_helicase PF00910.17 EGC33878.1 - 0.11 12.6 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase DUF1987 PF09345.5 EGC33880.1 - 0.013 15.2 1.0 0.027 14.2 0.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1987) DUF4584 PF15223.1 EGC33880.1 - 0.51 9.5 14.5 0.69 9.1 10.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4584) FNIP PF05725.7 EGC33883.1 - 7e-42 141.1 4.6 5.2e-17 61.5 0.0 3.0 1 1 1 3 3 3 3 FNIP Repeat DUF1769 PF08588.5 EGC33883.1 - 8.6e-05 22.4 4.3 1.9 8.5 0.1 3.8 1 1 3 4 4 4 3 Protein of unknown function (DUF1769) Phage_sheath_1 PF04984.9 EGC33885.1 - 0.039 12.3 1.4 0.046 12.1 1.0 1.0 1 0 0 1 1 1 0 Phage tail sheath protein Hydantoinase_A PF01968.13 EGC33885.1 - 0.16 11.0 0.2 0.17 10.9 0.2 1.0 1 0 0 1 1 1 0 Hydantoinase/oxoprolinase Apis_Csd PF11671.3 EGC33885.1 - 1.9 8.3 6.0 2.3 7.9 4.2 1.2 1 0 0 1 1 1 0 Complementary sex determiner protein DUF677 PF05055.7 EGC33886.1 - 0.046 12.3 0.0 0.053 12.1 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF677) PSP1 PF04468.7 EGC33886.1 - 0.057 13.3 0.1 5.4 7.0 0.0 2.3 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Patatin PF01734.17 EGC33887.1 - 3.2e-08 33.7 0.3 3.2e-08 33.7 0.2 2.4 3 0 0 3 3 3 1 Patatin-like phospholipase WW PF00397.21 EGC33887.1 - 0.00011 22.0 1.0 0.00034 20.4 0.7 2.0 1 0 0 1 1 1 1 WW domain Sugar_tr PF00083.19 EGC33888.1 - 2.2e-87 293.5 35.7 3e-87 293.0 24.7 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGC33888.1 - 4.5e-34 117.6 40.6 6.5e-26 90.8 13.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGC33888.1 - 5.1e-05 21.6 4.5 5.1e-05 21.6 3.1 1.7 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) ATG22 PF11700.3 EGC33888.1 - 0.00055 18.5 11.6 0.00055 18.5 8.0 2.7 1 1 2 3 3 3 1 Vacuole effluxer Atg22 like HABP4_PAI-RBP1 PF04774.10 EGC33889.1 - 6.2e-05 23.4 0.2 7.1e-05 23.2 0.1 1.1 1 0 0 1 1 1 1 Hyaluronan / mRNA binding family DUF1180 PF06679.7 EGC33891.1 - 0.53 10.1 2.4 1 9.2 1.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Glyco_hydro_16 PF00722.16 EGC33892.1 - 3.3e-11 42.8 0.5 3.3e-11 42.8 0.3 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 16 zf-RING_2 PF13639.1 EGC33893.1 - 3.1e-08 33.3 15.4 3.1e-08 33.3 10.7 1.7 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC33893.1 - 1.1e-05 25.4 11.2 3.8e-05 23.7 7.7 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC33893.1 - 3.2e-05 23.5 14.9 6.8e-05 22.4 10.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC33893.1 - 0.00091 18.8 20.4 0.00091 18.8 14.1 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33893.1 - 0.0022 18.0 18.5 0.0049 16.8 12.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) DUF393 PF04134.7 EGC33893.1 - 0.47 11.5 0.0 0.47 11.5 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function, DUF393 zf-RING_5 PF14634.1 EGC33893.1 - 1.1 9.0 22.3 0.2 11.4 12.6 2.0 2 0 0 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGC33893.1 - 1.3 8.6 17.3 0.21 11.1 8.9 2.1 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC33893.1 - 1.4 8.8 15.6 0.059 13.2 6.0 2.3 2 1 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC33893.1 - 1.7 8.5 15.3 6.9 6.6 10.6 2.1 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC33893.1 - 4.5 7.0 12.7 23 4.7 8.8 2.3 1 0 0 1 1 1 0 RING-type zinc-finger Ank_2 PF12796.2 EGC33894.1 - 0.00012 22.3 0.4 0.35 11.2 0.1 3.3 2 1 0 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC33894.1 - 0.12 12.6 5.9 16 6.0 0.1 4.9 6 0 0 6 6 6 0 Ankyrin repeat Peptidase_S28 PF05577.7 EGC33895.1 - 5.4e-117 391.0 4.5 6.2e-117 390.8 3.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Peptidase_S37 PF05576.6 EGC33895.1 - 0.0075 14.7 0.1 0.013 13.9 0.1 1.3 1 0 0 1 1 1 1 PS-10 peptidase S37 DUF3975 PF13126.1 EGC33898.1 - 0.5 10.5 5.7 0.84 9.8 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3975) CesA PF11439.3 EGC33898.1 - 0.67 9.9 4.9 0.4 10.6 0.2 2.7 3 0 0 3 3 3 0 Type III secretion system filament chaperone CesA DUF4463 PF14703.1 EGC33898.1 - 3.7 8.1 11.4 0.16 12.4 1.9 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4463) SnoaL_2 PF12680.2 EGC33899.1 - 2e-05 24.8 0.0 2.4e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGC33899.1 - 0.0021 17.6 0.1 0.0075 15.8 0.1 1.8 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF3271 PF11675.3 EGC33899.1 - 0.02 14.0 0.3 0.023 13.8 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) DUF4440 PF14534.1 EGC33899.1 - 0.036 14.2 0.0 0.039 14.1 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4440) SapB_2 PF03489.12 EGC33900.1 - 9.3e-07 28.7 1.2 9.8e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC33900.1 - 0.0042 16.8 2.0 0.0042 16.8 1.4 3.0 4 0 0 4 4 4 1 Saposin-like type B, region 1 PA14 PF07691.7 EGC33901.1 - 5.1e-17 61.8 0.1 9.1e-17 61.0 0.0 1.4 1 0 0 1 1 1 1 PA14 domain PA14 PF07691.7 EGC33902.1 - 6.6e-16 58.2 0.1 1.1e-15 57.5 0.0 1.4 1 0 0 1 1 1 1 PA14 domain DUF727 PF05303.7 EGC33904.1 - 2.7e-09 36.7 0.1 3.2e-09 36.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF727) UPF0728 PF15092.1 EGC33904.1 - 0.14 11.9 0.4 0.24 11.3 0.1 1.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0728 HTH_Tnp_Tc5 PF03221.11 EGC33905.1 - 3.2e-16 58.9 0.5 7e-16 57.8 0.4 1.6 1 0 0 1 1 1 1 Tc5 transposase DNA-binding domain BTB PF00651.26 EGC33906.1 - 1e-17 64.1 0.2 2.8e-17 62.7 0.1 1.7 1 0 0 1 1 1 1 BTB/POZ domain BACK PF07707.10 EGC33906.1 - 0.0014 18.4 1.5 0.027 14.3 0.4 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch DUF1390 PF07150.6 EGC33906.1 - 0.067 12.5 10.8 0.15 11.4 7.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Secretin_N_2 PF07655.8 EGC33906.1 - 1.1 9.6 21.6 2.9 8.3 15.0 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC33906.1 - 3.1 7.8 12.5 2.1 8.4 6.5 2.1 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) FNIP PF05725.7 EGC33907.1 - 2.7e-31 107.2 73.6 7.3e-08 32.2 1.0 13.1 6 3 8 14 14 14 13 FNIP Repeat ATG27 PF09451.5 EGC33908.1 - 3.7e-13 49.3 3.1 1.4e-11 44.1 2.1 2.3 1 1 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EGC33908.1 - 1.7e-06 27.2 0.1 2.8e-06 26.5 0.0 1.3 1 0 0 1 1 1 1 Mannose-6-phosphate receptor Consortin_C PF15281.1 EGC33908.1 - 0.28 10.6 0.8 0.57 9.7 0.1 1.8 2 0 0 2 2 2 0 Consortin C-terminus PepSY_TM_3 PF13706.1 EGC33908.1 - 2.3 7.7 6.4 4.8 6.6 4.4 1.5 1 0 0 1 1 1 0 PepSY-associated TM helix ADH_zinc_N PF00107.21 EGC33909.1 - 6.4e-26 90.4 0.0 1e-25 89.7 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC33909.1 - 3e-09 36.5 0.0 7.9e-08 32.0 0.0 2.8 2 1 1 3 3 3 1 Alcohol dehydrogenase GroES-like domain TrkA_N PF02254.13 EGC33909.1 - 0.0057 16.6 0.1 0.011 15.7 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain ADH_zinc_N_2 PF13602.1 EGC33909.1 - 0.02 15.8 0.0 0.054 14.3 0.0 1.8 2 0 0 2 2 2 0 Zinc-binding dehydrogenase AlaDh_PNT_C PF01262.16 EGC33909.1 - 0.023 14.2 0.0 0.052 13.1 0.0 1.6 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain SIS_2 PF13580.1 EGC33909.1 - 0.064 12.9 0.1 0.11 12.1 0.0 1.4 1 0 0 1 1 1 0 SIS domain TrkA_C PF02080.16 EGC33909.1 - 0.11 12.0 0.0 21 4.7 0.0 3.4 3 1 1 4 4 4 0 TrkA-C domain Ras PF00071.17 EGC33910.1 - 1.9e-26 92.3 0.0 2.7e-26 91.8 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33910.1 - 2.6e-12 47.2 0.0 8e-12 45.7 0.0 1.8 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC33910.1 - 1.3e-05 24.5 0.0 2.6e-05 23.5 0.0 1.6 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC33910.1 - 0.0002 20.6 0.0 0.00026 20.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGC33910.1 - 0.0017 17.8 0.0 0.0039 16.6 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGC33910.1 - 0.0057 16.6 0.0 0.038 13.9 0.0 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EGC33910.1 - 0.079 12.5 0.1 0.22 11.0 0.0 1.6 2 0 0 2 2 2 0 AAA domain I_LWEQ PF01608.12 EGC33912.1 - 6.9e-51 172.1 12.9 6.9e-51 172.1 8.9 4.6 5 1 0 5 5 5 2 I/LWEQ domain ANTH PF07651.11 EGC33912.1 - 3.1e-45 154.0 0.0 3.1e-45 154.0 0.0 3.6 4 1 0 4 4 4 1 ANTH domain ENTH PF01417.15 EGC33912.1 - 1.1e-09 38.2 1.1 1.2e-08 34.8 0.0 3.1 3 0 0 3 3 3 1 ENTH domain DUF2536 PF10750.4 EGC33912.1 - 0.13 11.8 2.1 0.3 10.7 0.4 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2536) DUF4094 PF13334.1 EGC33913.1 - 0.031 14.6 0.5 0.094 13.1 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4094) ABC2_membrane_3 PF12698.2 EGC33913.1 - 0.075 12.0 0.2 0.086 11.8 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Ctr PF04145.10 EGC33913.1 - 0.53 10.3 0.0 0.53 10.3 0.0 2.2 1 1 1 2 2 2 0 Ctr copper transporter family DUF1980 PF09323.5 EGC33913.1 - 1.5 8.5 6.5 0.34 10.6 1.1 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF1980) Med26 PF08711.6 EGC33914.1 - 0.073 12.5 0.1 0.095 12.2 0.1 1.2 1 0 0 1 1 1 0 TFIIS helical bundle-like domain FNIP PF05725.7 EGC33915.1 - 6.8e-61 201.9 19.8 5.2e-14 51.9 0.2 6.7 4 2 1 6 6 6 6 FNIP Repeat EGF_2 PF07974.8 EGC33916.1 - 1.1e-07 31.9 33.9 7.4e-05 22.8 5.8 3.1 3 0 0 3 3 3 2 EGF-like domain DUF3827 PF12877.2 EGC33916.1 - 0.031 12.3 2.6 0.053 11.6 1.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) SKG6 PF08693.5 EGC33916.1 - 0.21 10.9 10.0 0.099 11.9 5.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Laminin_EGF PF00053.19 EGC33916.1 - 1.1 9.2 22.0 4 7.4 4.3 2.7 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) Y_phosphatase2 PF03162.8 EGC33919.1 - 7.7e-43 145.7 0.0 8.4e-43 145.5 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGC33919.1 - 0.0018 18.5 0.0 0.0026 18.0 0.0 1.3 1 1 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGC33919.1 - 0.043 13.3 0.0 0.052 13.1 0.0 1.2 1 0 0 1 1 1 0 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC33919.1 - 0.1 11.8 0.0 0.12 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein-tyrosine phosphatase Nuc-transf PF10127.4 EGC33920.1 - 5.4e-09 35.7 0.4 9.5e-09 34.9 0.0 1.6 2 0 0 2 2 2 1 Predicted nucleotidyltransferase DUF4623 PF15416.1 EGC33920.1 - 0.07 11.4 1.6 0.15 10.4 0.2 2.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4623) EF-hand_1 PF00036.27 EGC33921.1 - 1.4e-10 39.7 2.0 0.00011 21.2 0.2 2.6 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGC33921.1 - 7.3e-08 32.4 0.6 1.5e-07 31.4 0.3 1.6 1 1 1 2 2 2 1 EF-hand domain pair EF-hand_6 PF13405.1 EGC33921.1 - 1.5e-06 27.5 0.1 0.059 13.2 0.0 2.6 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGC33921.1 - 0.00033 19.8 0.2 0.1 11.9 0.0 2.5 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGC33921.1 - 0.00076 19.0 0.2 0.0023 17.5 0.1 1.9 1 1 0 1 1 1 1 EF-hand domain pair SWIRM PF04433.12 EGC33921.1 - 0.085 12.9 0.0 0.14 12.3 0.0 1.3 1 0 0 1 1 1 0 SWIRM domain DUF3896 PF13035.1 EGC33921.1 - 4.4 7.4 6.4 8.6 6.4 1.2 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3896) ArfGap PF01412.13 EGC33922.1 - 2.1e-38 130.6 0.8 3.1e-38 130.1 0.2 1.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf PH PF00169.24 EGC33922.1 - 6.2e-15 55.2 0.3 1.1e-14 54.4 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC33922.1 - 6.7e-07 29.5 3.2 4.2e-06 26.9 0.9 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_3 PF14593.1 EGC33922.1 - 0.0012 18.6 0.3 0.0023 17.7 0.2 1.4 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGC33922.1 - 0.11 12.6 0.9 0.18 11.9 0.0 1.8 2 0 0 2 2 2 0 Pleckstrin homology domain Ras PF00071.17 EGC33923.1 - 5e-15 55.2 0.5 7.6e-15 54.6 0.3 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC33923.1 - 1.9e-13 50.9 0.6 6.2e-13 49.2 0.0 2.0 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EGC33923.1 - 0.00091 18.4 0.1 0.0023 17.1 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGC33923.1 - 0.0021 17.9 0.2 0.0074 16.2 0.1 2.1 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_24 PF13479.1 EGC33923.1 - 0.0028 17.2 0.6 0.017 14.6 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC33923.1 - 0.016 15.2 0.0 0.036 14.0 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain AAA PF00004.24 EGC33923.1 - 0.057 13.6 0.0 0.12 12.5 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GTP_EFTU PF00009.22 EGC33923.1 - 0.058 12.8 0.4 0.6 9.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain NB-ARC PF00931.17 EGC33923.1 - 0.14 10.9 0.0 0.14 10.9 0.0 2.1 2 1 1 3 3 3 0 NB-ARC domain Dynamin_N PF00350.18 EGC33923.1 - 0.17 11.7 0.1 0.17 11.7 0.1 2.2 2 1 0 2 2 2 0 Dynamin family AAA_18 PF13238.1 EGC33923.1 - 5.3 7.3 7.9 1.1 9.6 0.1 2.7 1 1 0 2 2 2 0 AAA domain RNB PF00773.14 EGC33924.1 - 4.1e-35 121.6 3.6 2.8e-33 115.6 0.3 5.1 3 2 3 6 6 6 2 RNB domain Poxvirus_B22R_C PF13168.1 EGC33925.1 - 0.11 11.7 0.7 0.23 10.7 0.1 1.8 2 0 0 2 2 2 0 Poxvirus B22R protein C-terminal RP-C_C PF11800.3 EGC33925.1 - 5.3 6.6 5.3 0.56 9.8 0.3 1.8 2 1 1 3 3 3 0 Replication protein C C-terminal region PX PF00787.19 EGC33926.1 - 3.7e-16 58.9 1.9 6.3e-16 58.1 1.3 1.3 1 0 0 1 1 1 1 PX domain CppA_C PF14507.1 EGC33926.1 - 0.078 13.1 0.0 0.34 11.1 0.0 2.1 2 0 0 2 2 2 0 CppA C-terminal HSP70 PF00012.15 EGC33927.1 - 1.7e-128 429.2 10.1 2.2e-128 428.8 7.0 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGC33927.1 - 3.9e-15 55.2 1.6 1.5e-14 53.3 0.9 1.8 2 0 0 2 2 2 1 MreB/Mbl protein AHS1 PF02682.11 EGC33927.1 - 0.0022 17.5 0.2 0.0097 15.3 0.1 2.0 2 0 0 2 2 2 1 Allophanate hydrolase subunit 1 PilM_2 PF11104.3 EGC33927.1 - 0.0079 15.1 2.5 0.028 13.2 1.7 1.9 1 1 0 1 1 1 1 Type IV pilus assembly protein PilM; TPP_enzyme_N PF02776.13 EGC33927.1 - 0.041 13.3 0.3 0.13 11.7 0.2 1.9 1 1 0 1 1 1 0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain B5 PF03484.10 EGC33927.1 - 0.1 12.4 0.3 0.57 10.0 0.2 2.4 1 1 0 1 1 1 0 tRNA synthetase B5 domain Dickkopf_N PF04706.7 EGC33928.1 - 0.0033 17.5 11.0 0.0033 17.5 7.6 6.5 4 2 3 7 7 7 2 Dickkopf N-terminal cysteine-rich region MSA-2c PF12238.3 EGC33928.1 - 0.11 12.0 2.6 0.22 11.1 1.8 1.4 1 0 0 1 1 1 0 Merozoite surface antigen 2c Glu_synthase PF01645.12 EGC33928.1 - 1.9 7.3 4.8 3.9 6.3 3.3 1.5 1 0 0 1 1 1 0 Conserved region in glutamate synthase RINGv PF12906.2 EGC33929.1 - 1.6e-15 56.8 8.4 3.4e-15 55.8 5.8 1.6 1 0 0 1 1 1 1 RING-variant domain zf-RING_2 PF13639.1 EGC33929.1 - 0.042 13.6 6.9 0.084 12.7 4.8 1.5 1 0 0 1 1 1 0 Ring finger domain Trypan_PARP PF05887.6 EGC33929.1 - 1.7 8.4 3.7 3.4 7.4 2.5 1.4 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) CytochromB561_N PF09786.4 EGC33930.1 - 0.0029 16.1 19.3 0.004 15.6 13.4 1.1 1 0 0 1 1 1 1 Cytochrome B561, N terminal Ly49 PF08391.5 EGC33930.1 - 0.0075 16.3 0.3 0.016 15.3 0.2 1.5 1 0 0 1 1 1 1 Ly49-like protein, N-terminal region WBP-1 PF11669.3 EGC33930.1 - 0.011 15.7 0.1 0.023 14.7 0.1 1.5 1 0 0 1 1 1 0 WW domain-binding protein 1 Pol_alpha_B_N PF08418.5 EGC33930.1 - 0.022 14.3 18.1 0.028 13.9 12.5 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal UPF0542 PF15086.1 EGC33930.1 - 0.056 13.1 0.3 0.088 12.5 0.2 1.3 1 0 0 1 1 1 0 Uncharacterised protein family UPF0542 7TM_GPCR_Sru PF10322.4 EGC33930.1 - 0.06 12.4 0.6 0.076 12.1 0.4 1.1 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru DUF2149 PF09919.4 EGC33930.1 - 0.076 13.1 0.7 0.14 12.2 0.5 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2149) Mcm10 PF09332.6 EGC33930.1 - 0.2 10.9 9.0 0.24 10.6 6.2 1.1 1 0 0 1 1 1 0 Mcm10 replication factor APC_CDC26 PF10471.4 EGC33930.1 - 0.31 11.7 10.7 1 10.1 7.4 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF2489 PF10675.4 EGC33930.1 - 1.3 8.7 13.3 0.4 10.3 5.7 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2489) DUF2217 PF10265.4 EGC33930.1 - 1.3 7.6 8.0 1.6 7.3 5.5 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) TSA PF03249.8 EGC33930.1 - 1.5 7.2 7.8 2.2 6.7 5.4 1.1 1 0 0 1 1 1 0 Type specific antigen DUF4493 PF14900.1 EGC33932.1 - 0.03 13.9 4.1 0.088 12.4 2.9 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4493) PapD-like PF14874.1 EGC33932.1 - 0.1 12.5 0.1 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Flagellar-associated PapD-like FA_desaturase PF00487.19 EGC33932.1 - 0.13 11.6 6.8 2.4 7.5 0.0 2.9 2 2 0 2 2 2 0 Fatty acid desaturase OAD_gamma PF04277.8 EGC33932.1 - 0.37 11.2 0.0 0.37 11.2 0.0 2.8 3 0 0 3 3 3 0 Oxaloacetate decarboxylase, gamma chain DUF1469 PF07332.6 EGC33932.1 - 5.4 6.7 8.1 0.47 10.1 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1469) DUF3112 PF11309.3 EGC33932.1 - 9.1 6.0 17.8 18 5.0 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3112) WD40 PF00400.27 EGC33933.1 - 3.8e-31 105.8 0.5 1.2e-05 24.9 0.1 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGC33933.1 - 3.2e-06 25.5 0.1 7.6e-05 21.0 0.0 2.5 2 1 0 2 2 2 1 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGC33933.1 - 1.7e-05 23.2 0.4 0.072 11.3 0.2 2.4 2 1 0 2 2 2 2 Cytochrome D1 heme domain BBS2_Mid PF14783.1 EGC33933.1 - 0.00019 21.1 0.1 0.017 14.9 0.0 2.5 2 0 0 2 2 2 1 Ciliary BBSome complex subunit 2, middle region eIF2A PF08662.6 EGC33933.1 - 0.00089 19.0 0.2 0.85 9.2 0.0 3.3 1 1 3 4 4 4 2 Eukaryotic translation initiation factor eIF2A Me-amine-dh_H PF06433.6 EGC33933.1 - 0.0092 14.6 0.0 0.06 11.9 0.0 2.0 2 0 0 2 2 2 1 Methylamine dehydrogenase heavy chain (MADH) Coatomer_WDAD PF04053.9 EGC33933.1 - 0.047 12.4 0.4 0.26 10.0 0.0 2.0 1 1 2 3 3 3 0 Coatomer WD associated region Nucleoporin_N PF08801.6 EGC33933.1 - 0.049 12.3 0.1 0.48 9.1 0.0 2.2 1 1 1 2 2 2 0 Nup133 N terminal like PQQ_2 PF13360.1 EGC33933.1 - 0.052 13.0 0.1 0.64 9.4 0.1 2.4 1 1 1 2 2 2 0 PQQ-like domain Cortex-I_coil PF09304.5 EGC33934.1 - 3.1e-41 139.7 25.3 3.1e-41 139.7 17.6 2.9 1 1 2 3 3 3 1 Cortexillin I, coiled coil CH PF00307.26 EGC33934.1 - 3.7e-33 113.7 0.0 4.4e-15 55.6 0.0 2.7 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC33934.1 - 3e-06 26.7 0.0 0.0076 15.8 0.0 2.9 2 1 0 2 2 2 2 CAMSAP CH domain FUSC PF04632.7 EGC33934.1 - 0.0033 15.9 5.6 0.0041 15.6 3.9 1.0 1 0 0 1 1 1 1 Fusaric acid resistance protein family DUF1664 PF07889.7 EGC33934.1 - 0.33 10.7 6.9 0.34 10.7 1.8 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1664) ERM PF00769.14 EGC33934.1 - 0.88 9.0 31.4 0.26 10.7 9.8 2.5 1 1 1 2 2 2 0 Ezrin/radixin/moesin family CENP-F_leu_zip PF10473.4 EGC33934.1 - 5.4 6.8 42.0 0.72 9.7 9.6 3.3 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_head PF00063.16 EGC33935.1 - 5.1e-223 742.0 15.6 2.5e-220 733.1 10.8 3.3 1 1 0 1 1 1 1 Myosin head (motor domain) DIL PF01843.14 EGC33935.1 - 1.6e-28 98.6 2.8 1.6e-28 98.6 1.9 2.5 2 0 0 2 2 2 1 DIL domain IQ PF00612.22 EGC33935.1 - 3e-13 48.1 8.4 0.0004 19.7 0.5 5.2 5 0 0 5 5 5 3 IQ calmodulin-binding motif Myosin_N PF02736.14 EGC33935.1 - 9.2e-05 22.0 4.8 9.2e-05 22.0 3.3 2.0 2 0 0 2 2 2 1 Myosin N-terminal SH3-like domain UPF0086 PF01868.11 EGC33935.1 - 0.02 14.5 0.0 0.078 12.6 0.0 2.0 1 0 0 1 1 1 0 Domain of unknown function UPF0086 AAA_22 PF13401.1 EGC33935.1 - 0.039 14.0 0.2 0.33 11.1 0.0 2.7 2 0 0 2 2 2 0 AAA domain ERM PF00769.14 EGC33935.1 - 0.09 12.2 22.0 0.3 10.5 15.2 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family PhyH PF05721.8 EGC33936.1 - 1e-15 58.4 0.0 1.7e-15 57.6 0.0 1.4 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) COG2 PF06148.6 EGC33936.1 - 0.48 10.2 4.3 10 5.9 0.7 2.4 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 IF-2B PF01008.12 EGC33937.1 - 2.9e-62 210.2 0.1 1.9e-60 204.2 0.0 2.0 1 1 0 1 1 1 1 Initiation factor 2 subunit family 2-oxoacid_dh PF00198.18 EGC33937.1 - 0.014 14.6 0.1 0.04 13.1 0.1 1.6 1 1 0 1 1 1 0 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Pantoate_ligase PF02569.10 EGC33938.1 - 1.3e-82 276.6 0.3 1.6e-82 276.4 0.2 1.0 1 0 0 1 1 1 1 Pantoate-beta-alanine ligase YABBY PF04690.8 EGC33938.1 - 0.057 13.6 0.1 0.092 12.9 0.1 1.3 1 0 0 1 1 1 0 YABBY protein EGF_2 PF07974.8 EGC33939.1 - 2.3e-14 53.2 42.4 4.4e-05 23.5 6.1 3.8 3 0 0 3 3 3 3 EGF-like domain LRR_4 PF12799.2 EGC33939.1 - 2.4e-05 23.8 3.2 9e-05 22.0 1.5 2.7 2 0 0 2 2 2 1 Leucine Rich repeats (2 copies) TIG PF01833.19 EGC33939.1 - 0.00017 21.5 8.6 0.0031 17.4 1.6 5.0 5 2 1 6 6 6 2 IPT/TIG domain LRR_8 PF13855.1 EGC33939.1 - 0.00031 20.4 2.2 0.0014 18.3 1.5 2.2 1 0 0 1 1 1 1 Leucine rich repeat LRR_1 PF00560.28 EGC33939.1 - 0.0012 18.5 5.9 5.2 7.4 0.3 5.2 4 0 0 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EGC33939.1 - 0.065 13.3 2.5 4.4 7.6 0.3 3.5 2 0 0 2 2 2 0 Leucine Rich repeat Laminin_EGF PF00053.19 EGC33939.1 - 0.1 12.5 36.7 0.26 11.2 4.3 3.7 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) SKG6 PF08693.5 EGC33939.1 - 0.2 11.0 4.7 0.37 10.1 3.3 1.4 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MMR_HSR1 PF01926.18 EGC33940.1 - 0.00038 20.3 0.0 0.0046 16.9 0.0 2.6 2 1 0 3 3 3 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC33940.1 - 0.027 13.7 0.0 0.057 12.6 0.0 1.6 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit GBP PF02263.14 EGC33940.1 - 0.033 13.2 0.0 0.057 12.4 0.0 1.3 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Dynamin_N PF00350.18 EGC33940.1 - 0.05 13.4 0.0 0.16 11.7 0.0 1.9 1 0 0 1 1 1 0 Dynamin family DUF258 PF03193.11 EGC33940.1 - 0.059 12.5 0.0 0.25 10.5 0.0 2.1 2 1 0 2 2 2 0 Protein of unknown function, DUF258 PDEase_II PF02112.10 EGC33941.1 - 7.4e-101 337.4 0.4 1e-100 336.9 0.3 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGC33941.1 - 0.0011 18.5 0.7 0.0073 15.8 0.5 2.2 1 1 0 1 1 1 1 Beta-lactamase superfamily domain IBR PF01485.16 EGC33943.1 - 1.3e-14 53.7 31.9 8.7e-09 35.1 6.9 4.3 3 1 1 4 4 4 2 IBR domain zf-C3HC4 PF00097.20 EGC33943.1 - 0.00061 19.3 5.0 0.00061 19.3 3.5 5.4 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC33943.1 - 0.0012 18.7 9.9 0.0012 18.7 6.9 4.6 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Arf PF00025.16 EGC33944.1 - 2.3e-59 199.5 0.0 2.8e-59 199.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC33944.1 - 3.3e-11 42.8 0.0 4.3e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC33944.1 - 8.3e-11 41.4 0.0 1.5e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC33944.1 - 9.9e-11 42.1 0.0 1.6e-10 41.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC33944.1 - 2.4e-09 36.7 0.0 3.1e-09 36.2 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGC33944.1 - 2.6e-06 26.4 6.3 0.00067 18.4 0.0 2.7 2 1 1 3 3 3 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EGC33944.1 - 1.7e-05 24.7 0.0 2.4e-05 24.2 0.0 1.4 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA PF00004.24 EGC33944.1 - 0.014 15.5 0.0 0.026 14.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 EGC33944.1 - 0.015 14.3 0.0 0.027 13.5 0.0 1.4 1 0 0 1 1 1 0 6-phosphofructo-2-kinase NACHT PF05729.7 EGC33944.1 - 0.016 14.8 1.0 2.7 7.6 0.0 2.2 2 0 0 2 2 2 0 NACHT domain SRP54 PF00448.17 EGC33944.1 - 0.023 14.1 0.6 0.053 12.9 0.3 1.7 2 1 0 2 2 2 0 SRP54-type protein, GTPase domain AAA_22 PF13401.1 EGC33944.1 - 0.074 13.1 0.1 0.34 11.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain ACT PF01842.20 EGC33944.1 - 0.076 12.5 0.1 2.5 7.6 0.1 2.2 1 1 0 1 1 1 0 ACT domain ABC_tran PF00005.22 EGC33944.1 - 0.087 13.1 0.1 0.11 12.7 0.1 1.6 1 1 0 1 1 1 0 ABC transporter AAA_33 PF13671.1 EGC33944.1 - 0.12 12.2 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain SMAP PF15477.1 EGC33944.1 - 0.25 11.6 2.0 0.45 10.8 1.4 1.4 1 0 0 1 1 1 0 Small acidic protein family Cofilin_ADF PF00241.15 EGC33945.1 - 3.6e-18 65.6 0.0 3e-13 49.7 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein DUF2183 PF09949.4 EGC33945.1 - 0.0076 16.1 0.1 0.35 10.8 0.0 3.1 2 1 0 4 4 4 1 Uncharacterized conserved protein (DUF2183) Imm33 PF15580.1 EGC33945.1 - 0.022 14.2 0.1 2.7 7.5 0.1 2.3 2 0 0 2 2 2 0 Immunity protein 33 EutH PF04346.7 EGC33946.1 - 0.067 12.1 0.2 1.2 8.0 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation protein, EutH zf-RING_2 PF13639.1 EGC33947.1 - 3.7e-10 39.4 6.8 6.3e-10 38.7 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC33947.1 - 1e-08 35.0 9.9 1.7e-08 34.3 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EGC33947.1 - 1.1e-08 35.3 65.8 1.1e-08 35.3 45.6 3.1 2 1 1 3 3 2 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4 PF00097.20 EGC33947.1 - 3e-08 33.1 10.0 8.1e-08 31.8 6.9 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC33947.1 - 3e-07 30.0 9.9 5.9e-07 29.1 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC33947.1 - 5.5e-07 29.1 8.1 1e-06 28.3 5.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC33947.1 - 3.6e-05 23.7 2.6 0.00011 22.1 1.8 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC33947.1 - 0.0018 18.1 6.6 0.0052 16.6 4.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC33947.1 - 0.0049 16.5 7.8 0.025 14.3 5.4 2.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-Nse PF11789.3 EGC33947.1 - 0.006 16.0 6.8 0.015 14.7 4.7 1.7 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGC33947.1 - 0.0068 15.9 7.6 0.014 14.9 5.3 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC33947.1 - 0.026 14.3 1.4 0.051 13.4 1.0 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC33947.1 - 0.11 12.0 6.4 0.21 11.1 4.5 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1272 PF06906.6 EGC33947.1 - 0.15 11.9 6.1 0.32 10.8 4.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EGC33947.1 - 0.87 9.1 5.6 4.5 6.9 3.9 2.2 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 DUF3439 PF11921.3 EGC33947.1 - 6.7 6.4 16.7 22 4.8 11.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Actin PF00022.14 EGC33948.1 - 8.4e-128 426.1 0.0 1e-127 425.8 0.0 1.0 1 0 0 1 1 1 1 Actin dCMP_cyt_deam_1 PF00383.17 EGC33950.1 - 5.8e-19 67.6 0.2 7e-19 67.3 0.1 1.1 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region dCMP_cyt_deam_2 PF08211.6 EGC33950.1 - 7.7e-09 35.6 0.1 1.3e-08 34.9 0.0 1.4 2 0 0 2 2 2 1 Cytidine and deoxycytidylate deaminase zinc-binding region LmjF365940-deam PF14421.1 EGC33950.1 - 0.044 13.1 1.5 0.3 10.4 0.0 2.0 1 1 1 2 2 2 0 A distinct subfamily of CDD/CDA-like deaminases Pirin PF02678.11 EGC33951.1 - 4.5e-36 122.9 0.1 7e-36 122.3 0.0 1.3 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGC33951.1 - 6.3e-19 67.9 0.0 9.1e-18 64.2 0.0 2.5 2 1 0 2 2 2 1 Pirin C-terminal cupin domain KOW PF00467.24 EGC33951.1 - 0.16 11.7 2.5 0.18 11.5 0.6 1.9 2 0 0 2 2 2 0 KOW motif DUF3605 PF12239.3 EGC33953.1 - 1.5e-21 76.9 2.9 4.7e-21 75.2 2.0 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3605) ATP-synt PF00231.14 EGC33953.1 - 0.075 12.3 0.7 0.32 10.3 0.3 1.8 1 1 1 2 2 2 0 ATP synthase MEDS PF14417.1 EGC33953.1 - 0.084 11.9 0.5 0.14 11.1 0.1 1.6 2 0 0 2 2 2 0 MEDS: MEthanogen/methylotroph, DcmR Sensory domain Methyltransf_PK PF05891.7 EGC33953.1 - 0.11 11.7 0.8 1.1 8.4 0.2 2.0 2 0 0 2 2 2 0 AdoMet dependent proline di-methyltransferase Myb_DNA-bind_3 PF12776.2 EGC33953.1 - 0.96 10.1 4.5 3.2 8.4 1.6 2.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain AAA_2 PF07724.9 EGC33954.1 - 6.6e-51 172.6 0.0 1.8e-49 167.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) ClpB_D2-small PF10431.4 EGC33954.1 - 2.5e-26 91.3 0.2 9.3e-26 89.5 0.1 2.1 1 0 0 1 1 1 1 C-terminal, D2-small domain, of ClpB protein AAA PF00004.24 EGC33954.1 - 2.8e-23 82.5 0.5 8.5e-13 48.6 0.0 3.2 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC33954.1 - 9.2e-16 57.8 0.0 9.3e-10 38.3 0.0 3.4 3 1 1 4 4 3 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC33954.1 - 3.3e-12 46.7 6.5 4.1e-05 23.6 0.0 4.9 4 1 1 5 5 5 3 AAA ATPase domain AAA_22 PF13401.1 EGC33954.1 - 7.3e-11 42.3 7.3 1.3e-05 25.3 0.0 5.2 2 2 3 5 5 5 2 AAA domain Sigma54_activat PF00158.21 EGC33954.1 - 4.1e-07 29.6 0.0 0.00026 20.5 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_14 PF13173.1 EGC33954.1 - 1.7e-06 27.9 0.0 0.075 12.9 0.0 3.5 3 0 0 3 3 3 2 AAA domain Mg_chelatase PF01078.16 EGC33954.1 - 3.4e-06 26.3 0.0 0.16 11.1 0.0 3.4 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGC33954.1 - 8.8e-06 25.2 0.0 0.047 13.0 0.0 2.9 3 0 0 3 3 3 2 IstB-like ATP binding protein AAA_17 PF13207.1 EGC33954.1 - 1.1e-05 26.2 3.0 0.035 14.9 0.0 3.7 3 1 0 3 3 3 2 AAA domain AAA_18 PF13238.1 EGC33954.1 - 6.4e-05 23.2 5.8 0.15 12.3 0.0 4.0 3 1 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EGC33954.1 - 0.00026 20.7 13.0 0.021 14.5 0.1 5.2 5 1 0 5 5 4 1 Archaeal ATPase RNA_helicase PF00910.17 EGC33954.1 - 0.00027 21.0 0.0 1.7 8.8 0.0 3.2 3 0 0 3 3 3 2 RNA helicase RuvB_N PF05496.7 EGC33954.1 - 0.00027 20.0 0.8 0.31 10.0 0.0 3.4 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGC33954.1 - 0.001 18.7 0.0 0.12 12.1 0.0 2.6 2 0 0 2 2 2 1 Part of AAA domain NACHT PF05729.7 EGC33954.1 - 0.0011 18.6 0.1 0.24 11.0 0.0 3.1 3 0 0 3 3 3 1 NACHT domain AAA_25 PF13481.1 EGC33954.1 - 0.0012 18.2 0.6 0.57 9.5 0.0 3.5 5 0 0 5 5 3 1 AAA domain AAA_28 PF13521.1 EGC33954.1 - 0.0014 18.5 0.6 3.1 7.7 0.0 3.6 4 1 0 4 4 3 1 AAA domain DUF258 PF03193.11 EGC33954.1 - 0.0021 17.2 0.0 1.4 8.0 0.0 2.6 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MobB PF03205.9 EGC33954.1 - 0.0036 16.9 0.0 0.69 9.6 0.0 2.9 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGC33954.1 - 0.0074 15.7 0.4 2 7.7 0.0 3.7 4 0 0 4 4 4 1 SRP54-type protein, GTPase domain AAA_3 PF07726.6 EGC33954.1 - 0.0075 15.8 0.0 8.3 6.0 0.0 3.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_24 PF13479.1 EGC33954.1 - 0.011 15.3 0.0 1.8 8.0 0.0 2.5 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGC33954.1 - 0.012 15.2 0.0 0.48 9.9 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_33 PF13671.1 EGC33954.1 - 0.017 14.9 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGC33954.1 - 0.02 15.2 1.2 4.9 7.4 0.0 3.3 3 0 0 3 3 3 0 ABC transporter AAA_29 PF13555.1 EGC33954.1 - 0.032 13.7 0.0 5.6 6.5 0.0 2.4 2 0 0 2 2 2 0 P-loop containing region of AAA domain UPF0079 PF02367.12 EGC33954.1 - 0.053 13.1 0.0 16 5.1 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 Miro PF08477.8 EGC33954.1 - 0.055 13.9 0.0 1.1 9.8 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein IncA PF04156.9 EGC33954.1 - 1.1 8.7 15.0 2.6 7.6 10.4 1.5 1 0 0 1 1 1 0 IncA protein Atg14 PF10186.4 EGC33954.1 - 9 5.1 12.6 16 4.2 8.7 1.3 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RRM_1 PF00076.17 EGC33955.1 - 2.3e-11 43.1 0.1 4.3e-11 42.2 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC33955.1 - 7.3e-11 41.8 0.0 1.3e-10 41.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC33955.1 - 0.00068 19.4 0.1 0.0011 18.7 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) adh_short PF00106.20 EGC33956.1 - 3e-21 76.0 0.0 3.8e-21 75.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC33956.1 - 4.4e-08 33.0 0.1 7.6e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC33956.1 - 1.9e-05 24.5 0.0 3e-05 23.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Saccharop_dh PF03435.13 EGC33956.1 - 0.0024 16.9 0.0 0.0028 16.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Eno-Rase_NADH_b PF12242.3 EGC33956.1 - 0.036 13.8 0.0 0.087 12.6 0.0 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NAD_binding_10 PF13460.1 EGC33956.1 - 0.047 13.6 0.0 0.084 12.8 0.0 1.6 1 1 0 1 1 1 0 NADH(P)-binding adh_short PF00106.20 EGC33957.1 - 6.7e-18 65.1 0.0 8.6e-18 64.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC33957.1 - 2.8e-05 23.8 0.0 3.8e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 KR domain SCAMP PF04144.8 EGC33958.1 - 2.8e-31 108.7 15.2 3.6e-31 108.4 10.5 1.1 1 0 0 1 1 1 1 SCAMP family MpPF26 PF07666.6 EGC33958.1 - 0.42 10.5 8.7 0.49 10.2 2.1 2.2 2 0 0 2 2 2 0 M penetrans paralogue family 26 Abhydrolase_6 PF12697.2 EGC33959.1 - 5.8e-32 111.4 0.0 6.7e-32 111.1 0.0 1.0 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC33959.1 - 7.6e-20 71.1 0.0 1.4e-19 70.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC33959.1 - 7.3e-18 64.9 0.1 6.1e-17 61.9 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold DLH PF01738.13 EGC33959.1 - 1.4e-07 31.0 0.0 0.003 16.8 0.0 2.6 2 1 0 2 2 2 2 Dienelactone hydrolase family Abhydrolase_2 PF02230.11 EGC33959.1 - 2.3e-07 30.5 0.0 0.0018 17.7 0.0 2.1 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase DUF2048 PF09752.4 EGC33959.1 - 9.1e-06 24.7 0.0 0.015 14.1 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2048) Hydrolase_4 PF12146.3 EGC33959.1 - 2.6e-05 24.0 0.0 4.2e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Putative lysophospholipase DUF915 PF06028.6 EGC33959.1 - 0.0012 17.9 0.0 0.062 12.3 0.0 2.2 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) BAAT_C PF08840.6 EGC33959.1 - 0.0013 18.4 0.0 0.041 13.5 0.0 2.1 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal FSH1 PF03959.8 EGC33959.1 - 0.0015 18.0 0.1 0.03 13.7 0.0 2.6 2 1 0 2 2 2 1 Serine hydrolase (FSH1) Lipase_3 PF01764.20 EGC33959.1 - 0.0018 17.8 0.0 0.0051 16.4 0.0 1.7 1 0 0 1 1 1 1 Lipase (class 3) LIP PF03583.9 EGC33959.1 - 0.0062 15.7 0.0 0.96 8.5 0.0 2.1 2 0 0 2 2 2 1 Secretory lipase UPF0227 PF05728.7 EGC33959.1 - 0.0069 16.1 0.0 0.74 9.5 0.0 2.2 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0227) Esterase PF00756.15 EGC33959.1 - 0.0099 15.3 0.0 0.015 14.7 0.0 1.5 1 0 0 1 1 1 1 Putative esterase Abhydrolase_4 PF08386.5 EGC33959.1 - 0.015 15.2 0.0 0.022 14.6 0.0 1.2 1 0 0 1 1 1 0 TAP-like protein PGAP1 PF07819.8 EGC33959.1 - 0.02 14.4 0.0 0.036 13.6 0.0 1.4 1 0 0 1 1 1 0 PGAP1-like protein Peptidase_S9 PF00326.16 EGC33959.1 - 0.035 13.3 0.0 7.4 5.7 0.0 2.2 2 0 0 2 2 2 0 Prolyl oligopeptidase family Ndr PF03096.9 EGC33959.1 - 0.04 12.3 0.0 0.075 11.4 0.0 1.4 1 0 0 1 1 1 0 Ndr family Esterase_phd PF10503.4 EGC33959.1 - 0.053 12.7 0.0 0.1 11.8 0.0 1.4 1 0 0 1 1 1 0 Esterase PHB depolymerase Thioesterase PF00975.15 EGC33959.1 - 0.11 12.6 0.1 0.5 10.5 0.0 2.1 3 0 0 3 3 2 0 Thioesterase domain LSPR PF06049.7 EGC33960.1 - 0.2 11.1 1.0 0.47 10.0 0.0 2.3 2 0 0 2 2 2 0 Coagulation Factor V LSPD Repeat DUF3753 PF12575.3 EGC33960.1 - 1.7 8.4 6.2 4.5 7.1 4.3 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3753) CTNNBL PF08216.6 EGC33961.1 - 7.4e-33 112.3 4.8 7.4e-33 112.3 3.3 3.7 2 1 0 2 2 2 1 Catenin-beta-like, Arm-motif containing nuclear NusB PF01029.13 EGC33961.1 - 0.043 13.7 0.6 0.043 13.7 0.4 3.1 4 0 0 4 4 4 0 NusB family ArsA_ATPase PF02374.10 EGC33962.1 - 3.5e-105 351.4 0.1 4.4e-105 351.0 0.1 1.1 1 0 0 1 1 1 1 Anion-transporting ATPase CbiA PF01656.18 EGC33962.1 - 8.1e-14 51.4 0.4 3.8e-13 49.2 0.3 1.9 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGC33962.1 - 1.3e-05 25.1 0.2 0.00022 21.2 0.0 2.5 2 1 0 2 2 2 1 AAA domain Fer4_NifH PF00142.13 EGC33962.1 - 5.9e-05 22.3 0.0 0.0001 21.5 0.0 1.4 1 0 0 1 1 1 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family YhjQ PF06564.7 EGC33962.1 - 0.0032 16.8 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 YhjQ protein SRP54 PF00448.17 EGC33962.1 - 0.0051 16.2 0.0 0.02 14.3 0.0 1.9 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain PhoH PF02562.11 EGC33962.1 - 0.049 12.8 0.0 0.15 11.2 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein MipZ PF09140.6 EGC33962.1 - 0.083 11.9 0.0 0.19 10.7 0.0 1.6 1 0 0 1 1 1 0 ATPase MipZ NB-ARC PF00931.17 EGC33962.1 - 0.084 11.7 0.0 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain IstB_IS21 PF01695.12 EGC33962.1 - 0.09 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGC33962.1 - 0.14 11.5 0.1 0.4 10.0 0.1 1.8 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGC33962.1 - 0.19 10.8 0.0 0.32 10.0 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin PH PF00169.24 EGC33963.1 - 3.5e-06 27.1 0.1 1.1e-05 25.5 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_8 PF15409.1 EGC33963.1 - 0.00036 20.5 0.1 0.00097 19.1 0.0 1.7 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EGC33963.1 - 0.001 19.3 0.7 0.013 15.7 0.2 2.9 2 1 0 2 2 2 1 Pleckstrin homology domain LysM PF01476.15 EGC33963.1 - 0.0023 17.7 0.1 0.0066 16.3 0.1 1.8 1 0 0 1 1 1 1 LysM domain UBA_4 PF14555.1 EGC33963.1 - 0.0035 16.8 0.0 0.01 15.3 0.0 1.7 1 0 0 1 1 1 1 UBA-like domain 7tm_7 PF08395.7 EGC33963.1 - 0.04 12.9 4.2 0.06 12.3 1.1 2.0 2 0 0 2 2 2 0 7tm Chemosensory receptor P4Ha_N PF08336.6 EGC33963.1 - 0.37 10.6 6.4 0.22 11.3 0.4 2.5 2 0 0 2 2 2 0 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Suf PF05843.9 EGC33963.1 - 7.3 6.2 16.6 1.2 8.7 4.4 2.4 2 0 0 2 2 2 0 Suppressor of forked protein (Suf) SmpB PF01668.13 EGC33964.1 - 0.026 14.3 0.7 0.22 11.3 0.1 2.6 2 0 0 2 2 2 0 SmpB protein Orthopox_A36R PF05950.6 EGC33966.1 - 0.0056 16.6 0.1 0.011 15.6 0.1 1.5 1 0 0 1 1 1 1 Orthopoxvirus A36R protein Mito_carr PF00153.22 EGC33967.1 - 1.5e-58 194.4 1.5 7.5e-26 89.6 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein CactinC_cactus PF09732.4 EGC33968.1 - 2.8e-06 26.9 0.1 4.4e-06 26.2 0.1 1.4 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein zf-met PF12874.2 EGC33968.1 - 4.2e-06 26.7 1.0 7.7e-06 25.9 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger of C2H2 type PPR_2 PF13041.1 EGC33970.1 - 2.8e-09 36.7 4.4 9.2e-05 22.3 0.0 5.3 4 1 1 5 5 5 2 PPR repeat family PPR PF01535.15 EGC33970.1 - 2.5e-06 27.0 9.3 0.081 12.9 0.0 5.8 8 0 0 8 8 8 2 PPR repeat PPR_1 PF12854.2 EGC33970.1 - 0.0034 16.8 0.0 7.7 6.0 0.0 4.1 4 0 0 4 4 4 1 PPR repeat DUF711 PF05167.7 EGC33970.1 - 0.027 13.1 0.4 0.077 11.6 0.0 1.9 2 1 0 2 2 2 0 Uncharacterised ACR (DUF711) PPR_3 PF13812.1 EGC33970.1 - 0.12 12.6 0.0 31 5.1 0.0 3.7 3 0 0 3 3 3 0 Pentatricopeptide repeat domain OGFr_N PF04664.8 EGC33971.1 - 1.3e-44 152.0 8.2 1.3e-44 152.0 5.7 2.2 2 1 0 2 2 2 1 Opioid growth factor receptor (OGFr) conserved region Pox_Ag35 PF03286.9 EGC33971.1 - 0.13 11.7 5.1 0.24 10.9 3.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Neur_chan_memb PF02932.11 EGC33971.1 - 2.1 8.1 6.5 3.6 7.4 4.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Aldo_ket_red PF00248.16 EGC33972.1 - 8.8e-58 195.3 0.0 1e-57 195.1 0.0 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family p450 PF00067.17 EGC33973.1 - 1.3e-62 211.8 1.8 1.5e-62 211.6 1.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Y_Y_Y PF07495.8 EGC33973.1 - 0.015 15.0 0.1 0.036 13.8 0.0 1.6 1 0 0 1 1 1 0 Y_Y_Y domain Ras PF00071.17 EGC33974.1 - 3.9e-40 136.8 1.3 3.6e-27 94.7 0.0 3.6 4 0 0 4 4 4 2 Ras family A2M_N_2 PF07703.9 EGC33974.1 - 2.7e-17 62.8 0.1 9e-17 61.1 0.1 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region Miro PF08477.8 EGC33974.1 - 1.3e-09 38.5 2.6 2.2e-05 24.9 0.0 4.3 4 0 0 4 4 4 2 Miro-like protein A2M_N PF01835.14 EGC33974.1 - 3.3e-09 36.9 0.0 3.2e-08 33.7 0.0 2.9 2 0 0 2 2 2 1 MG2 domain A2M PF00207.17 EGC33974.1 - 3.7e-05 23.2 0.5 0.00018 20.9 0.0 2.6 3 0 0 3 3 3 1 Alpha-2-macroglobulin family CENP-L PF13092.1 EGC33975.1 - 2.1e-07 30.8 0.1 4.7e-07 29.7 0.1 1.6 1 1 0 1 1 1 1 Kinetochore complex Sim4 subunit Fta1 CLTH PF10607.4 EGC33976.1 - 3.5e-36 124.0 3.0 6.1e-36 123.2 2.1 1.4 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain SPRY PF00622.23 EGC33976.1 - 2e-25 89.2 0.2 3.5e-25 88.4 0.1 1.4 1 0 0 1 1 1 1 SPRY domain LisH PF08513.6 EGC33976.1 - 0.00014 21.4 0.1 0.00032 20.3 0.1 1.6 1 0 0 1 1 1 1 LisH TFIID_90kDa PF04494.10 EGC33976.1 - 0.08 13.0 0.7 0.17 11.9 0.2 1.7 1 1 0 1 1 1 0 WD40 associated region in TFIID subunit AF0941-like PF14591.1 EGC33976.1 - 0.47 10.5 4.7 0.87 9.6 0.7 2.3 1 1 1 2 2 2 0 AF0941-like SR-25 PF10500.4 EGC33976.1 - 1.3 8.4 16.6 2.1 7.7 11.5 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein RhoGAP PF00620.22 EGC33978.1 - 8.5e-30 103.3 0.0 3.1e-29 101.5 0.0 1.9 2 0 0 2 2 2 1 RhoGAP domain Rad60-SLD PF11976.3 EGC33978.1 - 0.055 13.1 0.0 3.2 7.5 0.0 3.2 3 0 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like Iso_dh PF00180.15 EGC33979.1 - 3.4e-87 292.6 0.5 3.9e-87 292.4 0.3 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase Thioredoxin PF00085.15 EGC33980.1 - 1.9e-05 24.2 0.0 3.7e-05 23.3 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin Phosducin PF02114.11 EGC33980.1 - 0.00068 18.4 1.8 0.02 13.6 0.0 2.0 1 1 1 2 2 2 2 Phosducin EF-1_beta_acid PF10587.4 EGC33980.1 - 0.44 10.7 5.4 1.5 9.0 3.8 2.0 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region SAM_1 PF00536.25 EGC33981.1 - 3.4e-07 30.3 1.1 4.3e-07 29.9 0.1 1.7 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC33981.1 - 1.7e-05 24.5 0.1 4e-05 23.3 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EGC33981.1 - 0.0017 18.0 0.0 0.0044 16.7 0.0 1.7 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain EGF_2 PF07974.8 EGC33982.1 - 0.0005 20.1 13.0 0.0011 19.0 9.0 1.7 1 0 0 1 1 1 1 EGF-like domain DUF1744 PF08490.7 EGC33983.1 - 4.3e-98 328.4 3.1 1.1e-97 327.2 2.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF1744) DNA_pol_B_exo1 PF03104.14 EGC33983.1 - 5.7e-60 202.8 9.5 2.4e-59 200.8 6.6 2.2 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain DNA_pol_B PF00136.16 EGC33983.1 - 7.5e-22 77.7 4.0 7.5e-22 77.7 2.8 2.7 3 0 0 3 3 3 1 DNA polymerase family B DNA_pol_B_exo2 PF10108.4 EGC33983.1 - 1.4e-09 37.8 0.2 4.1e-07 29.7 0.0 2.8 2 0 0 2 2 2 2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB GDC-P PF02347.11 EGC33983.1 - 0.056 12.1 0.4 0.13 10.9 0.1 1.6 2 0 0 2 2 2 0 Glycine cleavage system P-protein Gluconate_2-dh3 PF13618.1 EGC33983.1 - 0.17 12.0 0.0 1 9.5 0.0 2.1 2 0 0 2 2 2 0 Gluconate 2-dehydrogenase subunit 3 UBA_2 PF08587.6 EGC33984.1 - 0.091 12.9 0.1 0.18 12.0 0.1 1.5 1 0 0 1 1 1 0 Ubiquitin associated domain (UBA) DUF1446 PF07287.6 EGC33985.1 - 1.8e-106 355.6 0.0 2.7e-106 355.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1446) FAD_binding_3 PF01494.14 EGC33986.1 - 5.8e-13 48.6 0.0 5.4e-12 45.4 0.0 2.1 1 1 0 1 1 1 1 FAD binding domain SE PF08491.5 EGC33986.1 - 4.4e-05 22.4 0.0 0.0025 16.7 0.0 2.2 2 0 0 2 2 2 2 Squalene epoxidase MFS_1 PF07690.11 EGC33987.1 - 3.9e-28 98.1 48.7 1.2e-20 73.6 21.0 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EGC33987.1 - 1.7e-21 76.3 21.3 1.9e-20 72.9 7.8 3.1 2 1 0 2 2 2 2 Ion channel regulatory protein UNC-93 Sugar_tr PF00083.19 EGC33987.1 - 5.1e-06 25.3 8.3 5.1e-06 25.3 5.7 2.7 2 1 0 2 2 2 1 Sugar (and other) transporter MFS_2 PF13347.1 EGC33987.1 - 0.00022 19.7 18.1 0.0099 14.3 12.6 2.5 1 1 0 1 1 1 1 MFS/sugar transport protein SMC_N PF02463.14 EGC33988.1 - 9.2e-40 136.2 52.7 1.1e-38 132.6 36.5 2.8 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGC33988.1 - 3.4e-24 85.1 0.0 1.4e-23 83.0 0.0 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_23 PF13476.1 EGC33988.1 - 4.1e-16 59.9 10.5 4.1e-16 59.9 7.3 7.2 2 2 3 5 5 5 1 AAA domain AAA_21 PF13304.1 EGC33988.1 - 3e-11 43.8 15.8 1.4e-08 35.0 1.3 5.6 3 2 3 6 6 6 2 AAA domain AAA_29 PF13555.1 EGC33988.1 - 9.7e-07 28.2 0.0 2.2e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_15 PF13175.1 EGC33988.1 - 0.00033 19.8 4.4 0.00033 19.8 3.0 4.7 2 2 1 4 4 4 1 AAA ATPase domain Reo_sigmaC PF04582.7 EGC33988.1 - 0.00063 19.0 22.1 0.023 13.8 0.7 5.2 4 1 0 5 5 5 3 Reovirus sigma C capsid protein ATG16 PF08614.6 EGC33988.1 - 0.0014 18.5 14.8 0.0014 18.5 10.3 6.1 4 2 1 6 6 6 3 Autophagy protein 16 (ATG16) IncA PF04156.9 EGC33988.1 - 0.0052 16.3 4.8 0.0052 16.3 3.3 6.2 4 1 1 5 5 5 3 IncA protein TPR_MLP1_2 PF07926.7 EGC33988.1 - 0.0056 16.4 1.9 0.0056 16.4 1.3 7.1 5 2 1 6 6 6 2 TPR/MLP1/MLP2-like protein DUF504 PF04457.7 EGC33989.1 - 0.00092 19.3 0.5 0.0065 16.5 0.4 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF504) YABBY PF04690.8 EGC33989.1 - 0.53 10.5 2.6 0.66 10.1 1.8 1.3 1 0 0 1 1 1 0 YABBY protein DUF2570 PF10828.3 EGC33989.1 - 0.54 9.8 8.4 0.98 9.0 5.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2570) DDHD PF02862.12 EGC33989.1 - 0.93 9.2 5.4 1.2 8.8 3.7 1.2 1 0 0 1 1 1 0 DDHD domain DUF342 PF03961.8 EGC33989.1 - 5.3 5.3 9.2 6.7 5.0 6.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) NmrA PF05368.8 EGC33990.1 - 1.8e-62 210.6 0.0 2.1e-62 210.4 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC33990.1 - 2.8e-13 50.2 0.0 3.9e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC33990.1 - 4e-08 32.3 0.1 8.1e-08 31.2 0.1 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC33990.1 - 2.3e-06 27.2 0.0 6.6e-05 22.4 0.0 2.2 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGC33990.1 - 0.00046 19.9 0.0 0.0047 16.6 0.0 2.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC33990.1 - 0.00083 19.3 0.0 0.0035 17.2 0.1 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGC33990.1 - 0.021 15.1 0.0 0.043 14.1 0.0 1.5 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGC33990.1 - 0.064 13.1 0.1 0.16 11.8 0.1 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus TrkA_N PF02254.13 EGC33990.1 - 0.12 12.4 0.0 0.19 11.7 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain ABC2_membrane_5 PF13346.1 EGC33990.1 - 0.13 11.5 0.1 0.23 10.7 0.0 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein NmrA PF05368.8 EGC33991.1 - 7.2e-63 211.9 0.0 8.6e-63 211.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC33991.1 - 1.8e-13 50.9 0.0 2.5e-13 50.4 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC33991.1 - 6.4e-08 31.6 0.1 1.2e-07 30.6 0.0 1.4 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC33991.1 - 5.3e-05 22.7 0.0 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family KR PF08659.5 EGC33991.1 - 0.00012 21.7 0.0 0.0013 18.4 0.0 2.2 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGC33991.1 - 0.00074 19.4 0.0 0.004 17.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Semialdhyde_dh PF01118.19 EGC33991.1 - 0.036 14.3 0.0 0.11 12.8 0.0 1.9 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGC33991.1 - 0.054 13.5 0.0 0.096 12.6 0.0 1.4 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EGC33991.1 - 0.093 12.6 0.1 0.22 11.4 0.1 1.9 1 1 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DnaJ PF00226.26 EGC33992.1 - 2.2e-28 97.7 1.0 3.9e-28 96.9 0.7 1.4 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGC33992.1 - 1.4e-24 85.7 1.6 1.4e-19 69.7 0.0 2.6 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGC33992.1 - 9.6e-16 57.6 18.4 1.7e-15 56.8 12.8 1.4 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGC33992.1 - 0.0014 18.3 10.4 0.1 12.3 2.5 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family MFS_1 PF07690.11 EGC33993.1 - 1.7e-30 105.9 35.9 3.8e-30 104.7 17.7 1.8 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGC33993.1 - 0.019 14.7 1.7 0.019 14.7 1.2 3.7 5 0 0 5 5 5 0 MFS_1 like family MFS_3 PF05977.8 EGC33993.1 - 1 7.4 10.9 0.24 9.4 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Metallophos PF00149.23 EGC33994.1 - 8.4e-41 139.5 0.1 1e-40 139.2 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Zn_ribbon_2 PF12674.2 EGC33994.1 - 0.12 12.7 0.3 6.9 7.0 0.0 2.5 2 1 0 2 2 2 0 Putative zinc ribbon domain Njmu-R1 PF15053.1 EGC33995.1 - 2.7e-23 82.3 9.5 2.7e-10 39.5 3.5 3.4 3 0 0 3 3 3 3 Mjmu-R1-like protein family RF-1 PF00472.15 EGC33996.1 - 1.6e-39 134.2 3.7 2.2e-39 133.7 2.6 1.2 1 0 0 1 1 1 1 RF-1 domain PCRF PF03462.13 EGC33996.1 - 5e-14 51.9 0.1 5e-14 51.9 0.1 2.0 2 0 0 2 2 2 1 PCRF domain FNIP PF05725.7 EGC33998.1 - 2.3e-14 53.0 54.6 1.2e-05 25.0 2.2 9.0 6 3 3 9 9 9 7 FNIP Repeat Dehydratase_MU PF02288.10 EGC33998.1 - 0.12 12.1 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Dehydratase medium subunit SNARE_assoc PF09335.6 EGC33999.1 - 1.3e-20 73.8 2.5 1.3e-20 73.8 1.8 2.3 1 1 1 2 2 2 1 SNARE associated Golgi protein Peptidase_M50 PF02163.17 EGC33999.1 - 2.8 6.8 5.5 2 7.3 1.4 2.2 1 1 0 1 1 1 0 Peptidase family M50 ATP_synt_I PF03899.10 EGC33999.1 - 5.4 7.2 15.4 3 8.0 2.4 2.6 2 1 0 2 2 2 0 ATP synthase I chain Claudin_3 PF06653.6 EGC34000.1 - 0.012 15.3 4.0 0.052 13.2 0.6 2.2 2 0 0 2 2 2 0 Tight junction protein, Claudin-like ATP1G1_PLM_MAT8 PF02038.11 EGC34000.1 - 0.11 11.5 0.6 0.32 10.0 0.4 1.9 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family DUF2755 PF10954.3 EGC34000.1 - 0.32 10.7 1.8 0.84 9.3 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2755) DUF1049 PF06305.6 EGC34000.1 - 0.45 10.0 3.5 10 5.6 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) Tetraspannin PF00335.15 EGC34000.1 - 0.92 8.7 7.1 5.8 6.1 0.1 2.3 2 1 0 2 2 2 0 Tetraspanin family GSH_synth_ATP PF03917.12 EGC34001.1 - 5.5e-115 383.8 3.4 6.9e-115 383.5 2.4 1.0 1 0 0 1 1 1 1 Eukaryotic glutathione synthase, ATP binding domain GSH_synthase PF03199.10 EGC34001.1 - 8.2e-34 115.8 0.1 3.2e-33 113.9 0.0 2.0 2 0 0 2 2 2 1 Eukaryotic glutathione synthase DUF713 PF05218.9 EGC34001.1 - 0.0062 16.2 2.8 0.013 15.1 0.9 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF713) MitoNEET_N PF10660.4 EGC34002.1 - 0.17 11.7 0.0 0.37 10.6 0.0 1.5 1 0 0 1 1 1 0 Iron-containing outer mitochondrial membrane protein N-terminus CBM49 PF09478.5 EGC34003.1 - 7.2e-19 67.6 0.6 9.8e-19 67.2 0.4 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 HTH_AraC PF00165.18 EGC34005.1 - 0.0092 15.7 0.1 1.5 8.7 0.0 2.9 2 0 0 2 2 2 2 Bacterial regulatory helix-turn-helix proteins, AraC family RWP-RK PF02042.10 EGC34005.1 - 0.016 15.0 0.2 0.035 13.9 0.1 1.5 1 0 0 1 1 1 0 RWP-RK domain PAP_assoc PF03828.14 EGC34007.1 - 1e-05 25.3 2.5 4.5e-05 23.3 1.4 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase DUF2380 PF09533.5 EGC34008.1 - 7.4e-08 32.0 2.2 7.9e-08 31.9 1.6 1.1 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) WD40 PF00400.27 EGC34009.1 - 4.6e-33 111.8 14.0 2.2e-08 33.6 0.4 7.3 6 1 0 6 6 6 6 WD domain, G-beta repeat SAE2 PF08573.5 EGC34009.1 - 1.1 9.9 5.0 1.2 9.9 0.4 2.9 3 0 0 3 3 3 0 DNA repair protein endonuclease SAE2/CtIP C-terminus Myosin_head PF00063.16 EGC34012.1 - 2.4e-260 865.4 3.3 3.8e-260 864.7 2.3 1.3 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC34012.1 - 4.8e-40 136.9 0.1 7.7e-40 136.3 0.1 1.3 1 0 0 1 1 1 1 Myosin tail IQ PF00612.22 EGC34012.1 - 1.8e-06 27.0 10.9 0.0012 18.3 0.3 3.0 2 0 0 2 2 2 2 IQ calmodulin-binding motif AAA_22 PF13401.1 EGC34012.1 - 0.0022 18.1 0.0 0.014 15.5 0.0 2.3 2 0 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC34012.1 - 0.0027 16.8 0.0 0.0071 15.4 0.0 1.7 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGC34012.1 - 0.008 16.4 0.0 0.035 14.4 0.0 2.1 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGC34012.1 - 0.026 13.7 0.1 0.62 9.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGC34012.1 - 0.031 14.2 0.0 0.21 11.5 0.0 2.3 3 0 0 3 3 3 0 AAA ATPase domain DUF2075 PF09848.4 EGC34012.1 - 0.042 12.8 1.9 0.11 11.4 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) AAA_17 PF13207.1 EGC34012.1 - 0.049 14.4 0.1 0.23 12.2 0.0 2.2 2 0 0 2 2 2 0 AAA domain Gtr1_RagA PF04670.7 EGC34013.1 - 2.1e-102 341.1 2.2 2.6e-102 340.8 1.5 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Ras PF00071.17 EGC34013.1 - 4e-10 39.3 0.0 8.5e-10 38.2 0.0 1.6 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGC34013.1 - 1.7e-07 30.6 0.1 2.5e-07 30.0 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC34013.1 - 7.2e-07 29.1 0.0 1.5e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC34013.1 - 6.1e-06 26.7 0.7 1.4e-05 25.6 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein PduV-EutP PF10662.4 EGC34013.1 - 0.02 14.4 0.1 0.16 11.4 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC34013.1 - 0.026 13.7 0.1 0.042 13.0 0.0 1.4 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit DUF1450 PF07293.6 EGC34013.1 - 0.03 14.2 0.2 4.3 7.3 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1450) ClpS PF02617.12 EGC34013.1 - 0.072 12.8 0.0 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 ATP-dependent Clp protease adaptor protein ClpS Ank_3 PF13606.1 EGC34014.1 - 6.5e-07 28.9 0.1 0.00011 22.1 0.0 3.8 3 0 0 3 3 3 1 Ankyrin repeat Ank_2 PF12796.2 EGC34014.1 - 3.7e-06 27.1 0.0 2.3e-05 24.6 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) PI3_PI4_kinase PF00454.22 EGC34014.1 - 1.5e-05 24.5 0.1 0.011 15.2 0.1 2.6 2 0 0 2 2 2 2 Phosphatidylinositol 3- and 4-kinase Ank PF00023.25 EGC34014.1 - 9.3e-05 22.0 0.0 0.00047 19.8 0.0 2.3 1 0 0 1 1 1 1 Ankyrin repeat Ank_4 PF13637.1 EGC34014.1 - 0.0014 19.0 0.2 0.0063 16.9 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC34014.1 - 0.027 14.7 0.0 0.33 11.2 0.0 2.6 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Tna_leader PF08053.6 EGC34014.1 - 0.028 13.7 1.3 0.084 12.2 0.9 1.8 1 0 0 1 1 1 0 Tryptophanese operon leader peptide EAL PF00563.15 EGC34015.1 - 0.023 14.1 0.0 0.048 13.1 0.0 1.5 1 0 0 1 1 1 0 EAL domain bZIP_1 PF00170.16 EGC34016.1 - 1.4e-08 34.5 7.5 1.4e-08 34.5 5.2 4.0 4 0 0 4 4 4 1 bZIP transcription factor bZIP_2 PF07716.10 EGC34016.1 - 2.6e-06 27.1 9.3 2.6e-06 27.1 6.5 5.4 4 1 0 4 4 4 1 Basic region leucine zipper FlaC_arch PF05377.6 EGC34016.1 - 0.079 12.8 0.3 0.079 12.8 0.2 4.4 6 0 0 6 6 6 0 Flagella accessory protein C (FlaC) Arfaptin PF06456.8 EGC34017.1 - 0.005 16.2 0.3 0.0067 15.7 0.2 1.2 1 0 0 1 1 1 1 Arfaptin-like domain EGF_2 PF07974.8 EGC34019.1 - 5.8 7.1 13.0 0.48 10.6 5.6 1.7 2 0 0 2 2 2 0 EGF-like domain TMPIT PF07851.8 EGC34020.1 - 3.5e-111 371.4 12.6 4.4e-111 371.1 8.7 1.1 1 0 0 1 1 1 1 TMPIT-like protein UPF0184 PF03670.8 EGC34020.1 - 0.025 14.7 0.9 0.025 14.7 0.6 1.9 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0184) Cep57_MT_bd PF06657.8 EGC34020.1 - 0.26 11.2 3.9 4.6 7.2 0.1 2.8 1 1 1 2 2 2 0 Centrosome microtubule-binding domain of Cep57 Myosin_tail_1 PF01576.14 EGC34020.1 - 0.27 8.8 16.5 0.38 8.4 11.4 1.2 1 0 0 1 1 1 0 Myosin tail Laminin_II PF06009.7 EGC34020.1 - 0.34 10.6 13.7 0.5 10.1 9.5 1.2 1 0 0 1 1 1 0 Laminin Domain II Phage_HK97_TLTM PF06120.6 EGC34020.1 - 0.78 9.0 6.3 1.2 8.4 4.3 1.2 1 0 0 1 1 1 0 Tail length tape measure protein DUF724 PF05266.9 EGC34020.1 - 7.1 6.2 12.6 0.89 9.1 4.7 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF724) IncA PF04156.9 EGC34020.1 - 7.8 6.0 8.6 15 5.0 6.0 1.4 1 0 0 1 1 1 0 IncA protein Myosin_head PF00063.16 EGC34021.1 - 7.4e-275 913.3 2.9 7.4e-275 913.3 2.0 4.7 3 1 0 4 4 4 1 Myosin head (motor domain) Myosin_tail_1 PF01576.14 EGC34021.1 - 1.4e-95 320.8 398.9 9.6e-53 179.1 113.8 6.4 1 1 6 7 7 7 6 Myosin tail Filament PF00038.16 EGC34021.1 - 8.1e-18 64.9 299.3 1.1e-05 25.0 13.3 10.2 2 1 6 10 10 10 8 Intermediate filament protein Myosin_N PF02736.14 EGC34021.1 - 6.3e-15 54.5 0.3 1.8e-14 53.1 0.2 1.9 1 0 0 1 1 1 1 Myosin N-terminal SH3-like domain IQ PF00612.22 EGC34021.1 - 0.0032 16.9 3.1 0.012 15.1 0.3 2.9 2 0 0 2 2 2 1 IQ calmodulin-binding motif AAA_19 PF13245.1 EGC34021.1 - 0.054 13.2 0.0 0.18 11.5 0.0 1.9 1 0 0 1 1 1 0 Part of AAA domain DUF773 PF05600.7 EGC34022.1 - 2.1e-65 221.4 39.9 2.2e-60 204.8 22.8 2.3 1 1 0 2 2 2 2 Protein of unknown function (DUF773) DUF4535 PF15054.1 EGC34022.1 - 0.078 12.4 0.2 0.078 12.4 0.1 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4535) SlyX PF04102.7 EGC34022.1 - 0.3 11.5 6.0 0.13 12.6 0.6 3.0 2 1 1 3 3 3 0 SlyX Integrase_1 PF12835.2 EGC34022.1 - 1.1 8.9 4.1 28 4.4 0.0 3.2 2 1 1 3 3 3 0 Integrase DUF3872 PF12988.2 EGC34023.1 - 0.075 12.5 0.0 0.12 11.9 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3872) MFS_1 PF07690.11 EGC34024.1 - 1.5e-38 132.4 14.5 3.6e-37 127.9 7.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC34024.1 - 4.7e-10 38.6 15.1 7.6e-10 37.9 10.5 1.3 1 0 0 1 1 1 1 Sugar (and other) transporter Mem_trans PF03547.13 EGC34024.1 - 2.1e-06 26.3 0.0 0.001 17.4 1.2 2.4 1 1 1 2 2 2 2 Membrane transport protein OATP PF03137.15 EGC34024.1 - 9.4e-06 23.9 5.1 0.00019 19.6 0.2 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EGC34024.1 - 0.0031 15.6 7.0 0.11 10.6 0.1 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector CDC45 PF02724.9 EGC34024.1 - 0.044 11.8 0.0 0.044 11.8 0.0 2.5 2 1 1 3 3 3 0 CDC45-like protein Mucin PF01456.12 EGC34024.1 - 7.5 6.3 13.4 0.34 10.6 5.0 1.8 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF4511 PF14974.1 EGC34025.1 - 0.1 12.3 0.0 0.29 10.8 0.0 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4511) CBS PF00571.23 EGC34026.1 - 2.6e-15 55.9 0.3 3.5e-11 42.7 0.0 2.4 2 0 0 2 2 2 2 CBS domain TT_ORF1 PF02956.9 EGC34026.1 - 5.7 5.2 10.6 7 4.9 7.3 1.1 1 0 0 1 1 1 0 TT viral orf 1 RRM_1 PF00076.17 EGC34027.1 - 9.2e-34 114.9 1.4 3.5e-16 58.5 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34027.1 - 1.4e-29 101.8 0.1 2.9e-16 59.1 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34027.1 - 2.3e-18 65.7 0.1 7.4e-09 35.3 0.0 2.1 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC34027.1 - 1.9e-08 33.9 0.0 0.0015 18.2 0.0 2.2 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SpoVG PF04026.7 EGC34027.1 - 0.038 14.0 0.0 1.2 9.1 0.0 2.4 2 1 0 2 2 2 0 SpoVG Calx-beta PF03160.9 EGC34027.1 - 0.11 12.4 0.0 0.42 10.5 0.0 1.9 2 0 0 2 2 2 0 Calx-beta domain NGF PF00243.13 EGC34028.1 - 0.01 15.5 1.0 0.013 15.2 0.7 1.2 1 0 0 1 1 1 0 Nerve growth factor family DUF2129 PF09902.4 EGC34028.1 - 0.13 12.0 3.4 0.066 13.0 0.9 1.7 1 1 1 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2129) Peptidase_S64 PF08192.6 EGC34028.1 - 0.16 10.2 1.1 0.16 10.2 0.8 1.0 1 0 0 1 1 1 0 Peptidase family S64 RCC1 PF00415.13 EGC34029.1 - 5e-67 221.9 18.2 2.2e-15 56.6 0.1 7.1 6 1 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat HECT PF00632.20 EGC34029.1 - 3.1e-57 194.1 5.2 1.2e-56 192.2 3.6 2.1 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) Pkinase PF00069.20 EGC34029.1 - 2.9e-40 138.0 0.0 1.2e-39 136.0 0.0 2.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34029.1 - 5.2e-26 91.2 0.0 1.3e-25 89.9 0.0 1.6 1 0 0 1 1 1 1 Protein tyrosine kinase RCC1_2 PF13540.1 EGC34029.1 - 8.8e-26 88.9 28.5 4.2e-07 29.4 0.1 6.6 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat Kdo PF06293.9 EGC34029.1 - 0.0063 15.6 0.0 0.013 14.5 0.0 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC34029.1 - 0.012 15.3 0.0 0.022 14.4 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family Endonuclease_5 PF04493.9 EGC34030.1 - 4.7e-42 143.6 0.0 7.5e-42 143.0 0.0 1.3 1 0 0 1 1 1 1 Endonuclease V SHOCT PF09851.4 EGC34030.1 - 0.093 12.2 0.1 0.16 11.4 0.1 1.4 1 0 0 1 1 1 0 Short C-terminal domain Metallophos PF00149.23 EGC34031.1 - 2.7e-45 154.2 0.3 3.3e-45 153.9 0.2 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase SRP54 PF00448.17 EGC34032.1 - 1.1e-73 246.9 1.4 1.8e-73 246.2 0.9 1.3 1 0 0 1 1 1 1 SRP54-type protein, GTPase domain SRP_SPB PF02978.14 EGC34032.1 - 8.7e-22 77.3 1.3 8.7e-22 77.3 0.9 3.4 2 1 0 2 2 2 1 Signal peptide binding domain SRP54_N PF02881.14 EGC34032.1 - 5.4e-13 48.8 4.7 5.4e-13 48.8 3.2 2.0 2 0 0 2 2 2 1 SRP54-type protein, helical bundle domain cobW PF02492.14 EGC34032.1 - 4.5e-06 26.2 0.6 2.6e-05 23.7 0.4 2.1 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain SRPRB PF09439.5 EGC34032.1 - 6.6e-06 25.4 0.3 0.011 14.9 0.1 2.7 2 0 0 2 2 2 2 Signal recognition particle receptor beta subunit AAA_33 PF13671.1 EGC34032.1 - 9.7e-05 22.2 0.1 0.00022 21.0 0.0 1.7 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGC34032.1 - 0.00017 21.3 1.5 0.00083 19.0 1.0 2.2 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B CbiA PF01656.18 EGC34032.1 - 0.00033 20.1 0.4 0.0016 17.8 0.3 2.1 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_16 PF13191.1 EGC34032.1 - 0.0014 18.6 0.0 0.0039 17.1 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain ArgK PF03308.11 EGC34032.1 - 0.0037 16.0 0.1 0.0088 14.8 0.1 1.6 1 1 0 1 1 1 1 ArgK protein AAA_30 PF13604.1 EGC34032.1 - 0.0054 16.3 0.3 0.019 14.5 0.1 2.1 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC34032.1 - 0.014 15.5 0.8 0.058 13.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EGC34032.1 - 0.031 14.4 2.2 0.47 10.6 0.2 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) APS_kinase PF01583.15 EGC34032.1 - 0.037 13.6 0.0 0.067 12.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_19 PF13245.1 EGC34032.1 - 0.099 12.4 0.2 0.53 10.0 0.0 2.2 2 0 0 2 2 2 0 Part of AAA domain AAA_17 PF13207.1 EGC34032.1 - 0.1 13.3 0.1 0.27 12.0 0.0 1.8 2 0 0 2 2 1 0 AAA domain AAA_25 PF13481.1 EGC34032.1 - 0.2 11.0 0.5 0.64 9.3 0.3 2.0 1 1 0 1 1 1 0 AAA domain L_biotic_typeA PF04604.8 EGC34032.1 - 5.3 6.7 5.9 24 4.6 1.2 3.1 3 0 0 3 3 3 0 Type-A lantibiotic Pox_P4A PF03395.9 EGC34033.1 - 0.11 10.0 1.2 0.11 10.0 0.8 1.0 1 0 0 1 1 1 0 Poxvirus P4A protein FNIP PF05725.7 EGC34034.1 - 1e-220 713.5 43.0 1.2e-15 57.1 0.3 14.4 3 2 8 17 17 17 17 FNIP Repeat DUF1769 PF08588.5 EGC34034.1 - 0.067 13.1 48.5 8.5 6.4 0.1 13.8 4 3 15 20 20 20 0 Protein of unknown function (DUF1769) zf-RVT PF13966.1 EGC34035.1 - 1.3e-06 28.5 1.0 4.3e-06 26.9 0.7 1.9 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GATA PF00320.22 EGC34035.1 - 0.0018 17.5 0.0 0.0042 16.4 0.0 1.6 1 0 0 1 1 1 1 GATA zinc finger FNIP PF05725.7 EGC34037.1 - 1.2e-196 636.5 65.6 6.5e-16 58.0 0.5 16.2 13 2 2 16 16 16 16 FNIP Repeat ADH_zinc_N PF00107.21 EGC34037.1 - 0.011 15.2 1.2 60 3.1 0.0 6.2 4 3 3 8 8 8 0 Zinc-binding dehydrogenase Pyr_redox_2 PF07992.9 EGC34038.1 - 8.7e-11 42.0 0.0 1.9e-10 40.9 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC34038.1 - 4e-09 36.8 0.0 0.035 14.1 0.0 3.2 2 1 1 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGC34038.1 - 7.7e-06 25.7 0.0 0.044 13.5 0.0 2.4 2 0 0 2 2 2 2 FAD-NAD(P)-binding DAO PF01266.19 EGC34038.1 - 0.0018 17.2 0.1 0.094 11.5 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGC34038.1 - 0.0022 17.0 0.0 0.13 11.1 0.0 2.1 2 0 0 2 2 2 1 Lycopene cyclase protein Pyr_redox PF00070.22 EGC34038.1 - 0.0034 17.7 0.2 0.14 12.5 0.0 2.7 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGC34038.1 - 0.0044 15.7 0.3 0.046 12.3 0.0 2.5 3 0 0 3 3 3 1 Tryptophan halogenase NAD_binding_8 PF13450.1 EGC34038.1 - 0.02 14.9 0.0 0.05 13.6 0.0 1.7 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain HI0933_like PF03486.9 EGC34038.1 - 0.09 11.2 0.0 0.24 9.8 0.0 1.7 1 1 0 1 1 1 0 HI0933-like protein TPR_12 PF13424.1 EGC34039.1 - 2.6e-08 33.6 22.5 0.0072 16.2 0.6 6.9 6 2 3 9 9 9 6 Tetratricopeptide repeat TPR_8 PF13181.1 EGC34039.1 - 5.2e-06 25.8 24.2 0.055 13.2 0.6 7.0 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC34039.1 - 0.0034 17.6 0.3 1.4 9.3 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC34039.1 - 0.12 12.2 5.6 27 4.8 0.0 4.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC34039.1 - 0.14 12.1 32.2 8.1 6.6 0.1 9.5 11 0 0 11 11 11 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC34039.1 - 0.28 11.7 13.9 18 6.0 0.1 6.2 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC34039.1 - 0.33 10.6 32.1 0.88 9.2 0.0 8.0 9 0 0 9 9 9 0 Tetratricopeptide repeat MFS_1 PF07690.11 EGC34040.1 - 3.4e-49 167.4 28.2 3.4e-49 167.4 19.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC34040.1 - 1.2e-08 34.0 30.2 6.3e-06 25.0 10.3 2.9 2 1 0 2 2 2 2 Sugar (and other) transporter OATP PF03137.15 EGC34040.1 - 0.0065 14.5 8.8 0.014 13.4 1.4 2.9 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family EGF_2 PF07974.8 EGC34041.1 - 0.00012 22.2 11.6 0.00029 20.9 8.1 1.7 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC34041.1 - 0.092 12.6 7.4 0.028 14.3 2.9 1.8 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EGC34041.1 - 0.13 12.2 7.4 0.18 11.7 4.1 2.0 2 0 0 2 2 2 0 EGF-like domain EF-hand_7 PF13499.1 EGC34042.1 - 0.061 13.4 0.4 0.13 12.4 0.3 1.6 1 0 0 1 1 1 0 EF-hand domain pair EF-hand_1 PF00036.27 EGC34042.1 - 0.077 12.3 0.1 0.46 9.9 0.1 2.1 2 0 0 2 2 2 0 EF hand Gelsolin PF00626.17 EGC34043.1 - 1.2e-76 252.3 10.6 1.1e-15 57.0 0.0 6.6 6 0 0 6 6 6 6 Gelsolin repeat VHP PF02209.14 EGC34043.1 - 1.8e-10 40.3 0.2 5e-10 38.9 0.1 1.9 1 0 0 1 1 1 1 Villin headpiece domain Lactamase_B_2 PF12706.2 EGC34044.1 - 1.3e-26 93.3 0.2 9.7e-26 90.5 0.2 2.2 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGC34044.1 - 8.4e-08 32.0 0.0 2.2e-07 30.7 0.0 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily DAG_kinase_N PF14513.1 EGC34044.1 - 0.12 12.5 2.9 10 6.3 0.1 2.6 2 0 0 2 2 2 0 Diacylglycerol kinase N-terminus G-alpha PF00503.15 EGC34045.1 - 1.9e-98 329.7 7.7 2.3e-98 329.4 5.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC34045.1 - 1.2e-12 47.4 2.3 1.3e-08 34.2 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGC34045.1 - 0.00071 20.0 0.2 0.48 10.9 0.0 3.2 2 1 0 2 2 2 2 Miro-like protein Sigma54_activat PF00158.21 EGC34045.1 - 0.0034 16.8 0.0 0.27 10.7 0.0 2.2 2 0 0 2 2 2 1 Sigma-54 interaction domain GTP_EFTU PF00009.22 EGC34045.1 - 0.0097 15.3 0.2 1 8.7 0.1 2.5 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain zf-His_Me_endon PF05551.6 EGC34047.1 - 0.00078 19.4 1.0 0.0024 17.8 0.7 1.8 1 0 0 1 1 1 1 Zinc-binding loop region of homing endonuclease DUF605 PF04652.11 EGC34047.1 - 0.01 15.2 12.8 0.014 14.7 8.9 1.2 1 0 0 1 1 1 0 Vta1 like Autophagy_N PF03986.8 EGC34048.1 - 2.1e-46 157.3 4.7 2.1e-46 157.3 3.2 1.9 1 1 1 2 2 2 1 Autophagocytosis associated protein (Atg3), N-terminal domain Autophagy_act_C PF03987.10 EGC34048.1 - 5.7e-30 103.2 0.5 1.5e-29 101.9 0.3 1.8 1 0 0 1 1 1 1 Autophagocytosis associated protein, active-site domain Autophagy_Cterm PF10381.4 EGC34048.1 - 2.6e-14 52.0 4.7 6e-14 50.8 3.2 1.7 1 0 0 1 1 1 1 Autophagocytosis associated protein C-terminal AF1Q PF15017.1 EGC34048.1 - 0.15 12.0 0.3 0.15 12.0 0.2 3.0 2 1 0 2 2 2 0 Drug resistance and apoptosis regulator Filo_glycop PF01611.11 EGC34048.1 - 6.5 5.4 8.9 5.7 5.6 4.4 1.8 1 1 1 2 2 2 0 Filovirus glycoprotein FH2 PF02181.18 EGC34049.1 - 6.9e-74 248.9 3.0 6.9e-74 248.9 2.1 3.9 4 0 0 4 4 4 2 Formin Homology 2 Domain Methyltransf_32 PF13679.1 EGC34049.1 - 2.3e-22 79.1 1.5 1.5e-21 76.5 1.1 2.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34049.1 - 0.02 15.3 0.6 0.077 13.4 0.1 2.4 2 0 0 2 2 2 0 Methyltransferase domain tRNA-synt_2c PF01411.14 EGC34051.1 - 2.1e-172 574.2 0.1 2.9e-172 573.7 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGC34051.1 - 5e-18 64.7 0.5 1.4e-17 63.2 0.3 1.9 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain PAP_assoc PF03828.14 EGC34052.1 - 1.4e-05 24.9 1.8 5.7e-05 22.9 1.0 2.0 2 0 0 2 2 2 1 Cid1 family poly A polymerase Alpha_adaptinC2 PF02883.15 EGC34052.1 - 0.077 13.3 0.8 11 6.4 0.0 2.5 1 1 1 2 2 2 0 Adaptin C-terminal domain DUF2380 PF09533.5 EGC34053.1 - 2.6e-14 53.0 3.0 3.1e-14 52.8 2.1 1.1 1 0 0 1 1 1 1 Predicted lipoprotein of unknown function (DUF2380) DDE_3 PF13358.1 EGC34055.1 - 6.3e-09 35.7 0.1 7.4e-09 35.5 0.1 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease Y_phosphatase3 PF13350.1 EGC34056.1 - 0.043 14.0 9.4 0.047 13.9 0.0 4.4 4 2 0 4 4 4 0 Tyrosine phosphatase family DUF647 PF04884.9 EGC34058.1 - 6.1e-101 336.8 0.4 8.3e-101 336.3 0.3 1.1 1 0 0 1 1 1 1 Vitamin B6 photo-protection and homoeostasis Piwi PF02171.12 EGC34059.1 - 1.9e-75 253.6 0.4 1.2e-74 251.0 0.0 2.2 2 0 0 2 2 2 1 Piwi domain PAZ PF02170.17 EGC34059.1 - 3.2e-22 78.2 1.6 7.9e-22 77.0 1.1 1.7 1 0 0 1 1 1 1 PAZ domain AhpC-TSA PF00578.16 EGC34060.1 - 2.5e-40 136.9 0.0 3.1e-40 136.7 0.0 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC34060.1 - 2.7e-28 98.3 0.0 3.3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EGC34060.1 - 2.3e-06 27.6 0.0 3.5e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like AhpC-TSA_2 PF13911.1 EGC34060.1 - 0.0019 18.1 0.0 0.0029 17.5 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme DUF899 PF05988.7 EGC34060.1 - 0.0048 16.3 0.0 0.0053 16.2 0.0 1.0 1 0 0 1 1 1 1 Bacterial protein of unknown function (DUF899) FNIP PF05725.7 EGC34061.1 - 1.9e-19 69.3 63.4 2.5e-06 27.3 0.3 12.4 7 3 7 15 15 15 12 FNIP Repeat Gtr1_RagA PF04670.7 EGC34062.1 - 0.054 12.6 0.8 0.054 12.6 0.5 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region zf-CCHC PF00098.18 EGC34064.1 - 1.9e-06 27.4 1.3 3e-06 26.8 0.9 1.3 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGC34064.1 - 0.17 11.6 1.6 0.34 10.6 1.1 1.5 1 0 0 1 1 1 0 Zinc knuckle DDDD PF10161.4 EGC34065.1 - 0.00023 20.6 8.2 30 4.3 0.0 7.2 7 1 0 8 8 8 5 Putative mitochondrial precursor protein RRS1 PF04939.7 EGC34066.1 - 4.3e-49 166.1 8.0 4.3e-49 166.1 5.5 2.2 2 1 0 2 2 2 1 Ribosome biogenesis regulatory protein (RRS1) RRM_1 PF00076.17 EGC34067.1 - 2.2e-61 203.4 5.2 1.2e-19 69.6 0.1 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34067.1 - 1.2e-41 140.5 1.9 5.4e-14 51.9 0.0 3.7 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34067.1 - 1.5e-27 95.1 6.0 1e-09 38.0 0.4 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1877 PF08974.5 EGC34067.1 - 0.0085 15.7 0.2 4.3 6.9 0.0 3.9 3 1 1 4 4 4 1 Domain of unknown function (DUF1877) RNA_bind PF08675.6 EGC34067.1 - 0.01 15.7 0.1 0.55 10.2 0.0 3.4 3 0 0 3 3 3 0 RNA binding domain Dynamitin PF04912.9 EGC34068.1 - 3.3e-128 427.7 34.5 3.8e-128 427.5 23.9 1.0 1 0 0 1 1 1 1 Dynamitin FlaC_arch PF05377.6 EGC34068.1 - 0.3 11.0 22.4 1.6 8.6 0.1 5.6 3 2 1 4 4 4 0 Flagella accessory protein C (FlaC) Pox_A_type_inc PF04508.7 EGC34068.1 - 0.85 9.5 14.6 1.2 9.0 0.5 4.9 5 0 0 5 5 5 0 Viral A-type inclusion protein repeat Mannitol_dh PF01232.18 EGC34068.1 - 3.4 7.5 12.9 0.081 12.8 1.9 2.6 2 1 0 2 2 2 0 Mannitol dehydrogenase Rossmann domain PARP PF00644.15 EGC34070.1 - 1.6e-17 63.6 0.6 1.6e-13 50.5 0.0 2.7 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain DUF3125 PF11323.3 EGC34070.1 - 0.0046 16.6 0.1 0.0086 15.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3125) Actin PF00022.14 EGC34073.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC34073.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) Nckap1 PF09735.4 EGC34074.1 - 4.7e-200 666.8 12.3 5.5e-200 666.6 8.6 1.0 1 0 0 1 1 1 1 Membrane-associated apoptosis protein DUF4375 PF14300.1 EGC34074.1 - 0.55 10.2 6.9 10 6.1 0.1 3.6 4 0 0 4 4 4 0 Domain of unknown function (DUF4375) G-patch PF01585.18 EGC34075.1 - 1.6e-12 46.9 1.9 2.9e-12 46.1 1.3 1.4 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGC34075.1 - 0.0051 16.6 0.5 0.0051 16.6 0.3 2.4 3 1 0 3 3 3 1 DExH-box splicing factor binding site zf-DBF PF07535.7 EGC34075.1 - 0.056 13.1 0.6 0.11 12.1 0.4 1.4 1 0 0 1 1 1 0 DBF zinc finger ketoacyl-synt PF00109.21 EGC34076.1 - 1.7e-64 217.7 0.0 2.7e-64 217.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34076.1 - 3.8e-53 180.8 0.0 6.1e-53 180.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34076.1 - 2.2e-30 104.9 0.0 3.9e-30 104.1 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EGC34076.1 - 1.3e-26 93.0 0.0 2.5e-26 92.1 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein KR PF08659.5 EGC34076.1 - 5.9e-26 91.2 0.0 1e-23 83.9 0.0 2.8 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC34076.1 - 8.9e-17 61.4 0.0 5.9e-14 52.3 0.0 2.5 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 EGC34076.1 - 9.8e-13 47.9 0.0 1.5e-12 47.3 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC34076.1 - 1.4e-09 38.9 0.0 5e-09 37.1 0.0 2.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGC34076.1 - 1e-07 32.3 0.0 7.6e-07 29.5 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EGC34076.1 - 5e-07 29.4 0.0 1.3e-06 28.1 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC34076.1 - 1.1e-06 28.4 0.0 2.8e-06 27.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EGC34076.1 - 1.3e-06 28.6 0.0 0.003 17.6 0.0 2.4 2 0 0 2 2 2 2 NADH(P)-binding Epimerase PF01370.16 EGC34076.1 - 1.7e-05 24.3 0.1 0.0008 18.9 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family PP-binding PF00550.20 EGC34076.1 - 0.0033 17.6 0.1 0.0097 16.1 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EGC34076.1 - 0.0085 16.6 0.0 0.07 13.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Thiolase_N PF00108.18 EGC34076.1 - 0.026 13.4 0.0 0.051 12.5 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 EGC34076.1 - 0.18 12.3 0.0 1 9.8 0.0 2.4 1 1 0 1 1 1 0 Methyltransferase domain 2OG-FeII_Oxy_3 PF13640.1 EGC34077.1 - 1.7e-09 38.1 0.0 1.3e-08 35.2 0.0 2.3 2 1 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGC34077.1 - 1.7e-06 27.5 0.7 4.8e-06 26.1 0.2 1.9 1 1 1 2 2 2 1 2OG-Fe(II) oxygenase superfamily Pox_C4_C10 PF03336.8 EGC34077.1 - 0.00087 18.1 0.0 0.25 10.0 0.0 2.2 2 0 0 2 2 2 2 Poxvirus C4/C10 protein TPR_8 PF13181.1 EGC34077.1 - 0.075 12.8 0.1 0.25 11.2 0.1 1.9 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1768 PF08719.6 EGC34078.1 - 4.2e-39 133.7 0.0 4.9e-39 133.5 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) PARP PF00644.15 EGC34079.1 - 9.4e-16 57.8 5.4 6.6e-14 51.8 0.3 2.4 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain adh_short PF00106.20 EGC34079.1 - 1.5e-06 28.2 0.0 2.1e-06 27.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC34079.1 - 0.063 13.0 0.0 0.09 12.5 0.0 1.2 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase HPIH PF13323.1 EGC34080.1 - 0.17 11.5 0.7 11 5.7 0.1 2.1 1 1 1 2 2 2 0 N-terminal domain with HPIH motif FNIP PF05725.7 EGC34081.1 - 3.2e-89 292.6 136.2 4.4e-14 52.1 1.0 11.8 4 1 12 16 16 16 16 FNIP Repeat DUF1769 PF08588.5 EGC34081.1 - 0.00015 21.5 2.6 3.5 7.6 0.0 5.9 7 1 0 7 7 7 2 Protein of unknown function (DUF1769) Dyp_perox PF04261.7 EGC34082.1 - 2.1e-79 266.5 0.0 2.5e-79 266.2 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family Coagulase PF08764.5 EGC34082.1 - 0.048 13.5 0.1 0.087 12.7 0.1 1.3 1 0 0 1 1 1 0 Staphylococcus aureus coagulase Spatacsin_C PF14649.1 EGC34083.1 - 4.6e-102 340.8 6.3 1.4e-101 339.2 4.4 1.9 1 0 0 1 1 1 1 Spatacsin C-terminus FNIP PF05725.7 EGC34085.1 - 1.5e-34 117.7 60.9 1.9e-08 34.0 0.5 11.7 7 4 4 11 11 11 10 FNIP Repeat RNase_T PF00929.19 EGC34087.1 - 1.4e-32 113.2 0.1 1.6e-32 113.0 0.1 1.0 1 0 0 1 1 1 1 Exonuclease RE_NgoBV PF09564.5 EGC34087.1 - 0.0052 16.0 0.0 0.0067 15.6 0.0 1.2 1 0 0 1 1 1 1 NgoBV restriction endonuclease AAA_12 PF13087.1 EGC34088.1 - 1.9e-14 53.4 0.0 1.9e-14 53.4 0.0 3.7 1 1 2 4 4 4 1 AAA domain R3H PF01424.17 EGC34088.1 - 7.5e-14 51.1 0.0 2.1e-13 49.7 0.0 1.8 1 0 0 1 1 1 1 R3H domain AAA_11 PF13086.1 EGC34088.1 - 2.9e-10 40.1 0.9 2.9e-10 40.1 0.6 3.6 2 1 0 2 2 2 1 AAA domain zf-AN1 PF01428.11 EGC34088.1 - 2.1e-08 33.9 8.5 4.1e-08 32.9 5.9 1.4 1 0 0 1 1 1 1 AN1-like Zinc finger CTP_transf_1 PF01148.15 EGC34089.1 - 3.3e-09 36.7 13.5 8.1e-09 35.5 9.4 1.6 1 1 0 1 1 1 1 Cytidylyltransferase family Polysacc_synt PF01943.12 EGC34089.1 - 0.0026 17.0 6.4 0.0026 17.0 4.4 1.9 1 1 1 2 2 2 1 Polysaccharide biosynthesis protein LRR_1 PF00560.28 EGC34090.1 - 0.0024 17.6 0.2 0.11 12.5 0.1 2.4 2 0 0 2 2 2 1 Leucine Rich Repeat LRR_6 PF13516.1 EGC34090.1 - 0.0029 17.5 0.4 1.1 9.4 0.3 2.4 2 0 0 2 2 2 2 Leucine Rich repeat LRR_8 PF13855.1 EGC34090.1 - 0.022 14.4 0.1 0.067 12.9 0.1 1.7 2 0 0 2 2 2 0 Leucine rich repeat LRR_4 PF12799.2 EGC34090.1 - 0.036 13.6 0.1 1.2 8.8 0.1 2.1 2 0 0 2 2 2 0 Leucine Rich repeats (2 copies) NHL PF01436.16 EGC34091.1 - 0.00013 21.7 4.9 5.9 7.0 0.2 5.2 6 0 0 6 6 6 2 NHL repeat SBBP PF06739.6 EGC34091.1 - 0.019 14.7 3.4 9.6 6.0 0.1 3.7 3 0 0 3 3 3 0 Beta-propeller repeat Reg_prop PF07494.6 EGC34091.1 - 0.033 14.1 0.2 0.2 11.7 0.1 2.4 1 0 0 1 1 1 0 Two component regulator propeller Dyp_perox PF04261.7 EGC34092.1 - 2.4e-122 407.5 0.0 2.7e-61 207.0 0.0 2.0 1 1 1 2 2 2 2 Dyp-type peroxidase family VirB8 PF04335.8 EGC34092.1 - 0.016 14.7 0.0 1.1 8.7 0.0 2.1 2 0 0 2 2 2 0 VirB8 protein Glyco_hydro_44 PF12891.2 EGC34092.1 - 0.067 12.6 0.0 2.3 7.6 0.0 2.4 2 0 0 2 2 2 0 Glycoside hydrolase family 44 Dyp_perox PF04261.7 EGC34093.1 - 1.6e-70 237.3 0.1 1.8e-70 237.1 0.0 1.0 1 0 0 1 1 1 1 Dyp-type peroxidase family zf-C3HC4_3 PF13920.1 EGC34094.1 - 6.7e-09 35.2 6.9 1.2e-08 34.5 4.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-CCCH PF00642.19 EGC34094.1 - 9.9e-09 34.6 1.4 9.9e-09 34.6 1.0 1.8 2 0 0 2 2 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-C3HC4_2 PF13923.1 EGC34094.1 - 5.5e-08 32.6 11.0 1.1e-07 31.7 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC34094.1 - 3.6e-07 29.8 11.6 7.5e-07 28.7 8.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC34094.1 - 3.2e-06 26.6 13.4 8.5e-06 25.3 9.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC34094.1 - 4.6e-06 26.3 6.9 8.4e-06 25.5 4.8 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGC34094.1 - 0.0015 18.4 8.8 0.0037 17.0 6.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC34094.1 - 0.017 14.8 8.3 0.054 13.2 5.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-CCCH_2 PF14608.1 EGC34094.1 - 0.029 14.3 0.5 0.029 14.3 0.3 3.1 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type zf-RING_6 PF14835.1 EGC34094.1 - 0.095 12.4 1.1 0.19 11.5 0.8 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGC34094.1 - 0.2 11.7 7.3 0.82 9.8 5.0 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-Nse PF11789.3 EGC34094.1 - 0.44 10.1 5.8 1.2 8.7 4.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit DUF4118 PF13493.1 EGC34095.1 - 4.4 7.5 9.4 2.8 8.1 3.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4118) Ribosomal_S30 PF04758.9 EGC34096.1 - 3.2e-27 94.0 10.7 3.6e-27 93.8 7.4 1.0 1 0 0 1 1 1 1 Ribosomal protein S30 RAI1 PF08652.6 EGC34097.1 - 0.41 10.4 2.5 0.53 10.0 0.1 2.4 3 0 0 3 3 3 0 RAI1 like PD-(D/E)XK nuclease DUF2312 PF10073.4 EGC34098.1 - 0.45 9.8 3.3 0.6 9.5 1.4 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2312) MIP-T3 PF10243.4 EGC34099.1 - 0.0036 15.8 91.5 0.011 14.2 63.4 1.7 1 1 0 1 1 1 1 Microtubule-binding protein MIP-T3 Pkinase_Tyr PF07714.12 EGC34101.1 - 3.1e-67 226.3 0.1 2.2e-66 223.5 0.0 2.3 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGC34101.1 - 2.5e-59 200.5 0.0 2.5e-59 200.5 0.0 2.9 2 0 0 2 2 2 1 Protein kinase domain Kelch_5 PF13854.1 EGC34101.1 - 7.4e-31 105.5 1.8 3.1e-05 23.7 0.1 6.9 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGC34101.1 - 6e-29 99.5 10.4 4.6e-09 36.2 0.0 7.0 7 0 0 7 7 7 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC34101.1 - 8.2e-29 99.1 13.0 1e-09 37.9 0.1 6.8 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC34101.1 - 1.7e-17 62.7 10.2 2.1e-05 24.4 0.0 6.3 5 1 1 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EGC34101.1 - 9.4e-17 60.2 10.0 0.00018 20.9 0.0 6.7 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC34101.1 - 2.5e-12 46.0 17.4 0.00011 21.7 0.0 6.3 7 0 0 7 7 7 4 Kelch motif PX PF00787.19 EGC34101.1 - 2.1e-07 30.7 0.9 6.7e-07 29.1 0.1 2.3 2 0 0 2 2 2 1 PX domain APH PF01636.18 EGC34101.1 - 0.46 10.1 0.4 1 9.0 0.0 1.7 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF3276 PF11680.3 EGC34102.1 - 3.7 7.3 11.6 7.1 6.4 0.1 3.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3276) Rap_GAP PF02145.10 EGC34104.1 - 1.2e-55 187.7 0.2 7.4e-55 185.2 0.0 2.3 2 0 0 2 2 2 1 Rap/ran-GAP Terpene_synth_C PF03936.11 EGC34105.1 - 8.3e-08 31.7 3.4 1.5e-07 30.9 2.4 1.4 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain Glyco_transf_22 PF03901.12 EGC34106.1 - 1.5e-45 155.9 32.0 2e-45 155.5 22.2 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family Dicty_CTDC PF00526.13 EGC34107.1 - 4.4e-05 23.2 29.3 0.00059 19.6 5.9 5.1 5 1 0 5 5 5 3 Dictyostelium (slime mold) repeat GpcrRhopsn4 PF10192.4 EGC34108.1 - 1.1e-40 139.5 33.9 1.5e-40 139.0 23.5 1.2 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain GpcrRhopsn4 PF10192.4 EGC34109.1 - 7.6e-42 143.2 27.4 9.7e-42 142.9 19.0 1.1 1 0 0 1 1 1 1 Rhodopsin-like GPCR transmembrane domain DUF4184 PF13803.1 EGC34109.1 - 1 8.6 15.3 0.18 11.0 2.3 3.0 1 1 1 3 3 3 0 Domain of unknown function (DUF4184) GpcrRhopsn4 PF10192.4 EGC34110.1 - 1.6e-58 197.9 38.1 1.6e-58 197.9 26.4 2.0 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 EGC34110.1 - 5.5e-06 25.5 27.1 5.5e-06 25.5 18.8 1.5 2 0 0 2 2 2 1 Lung seven transmembrane receptor Acyl_transf_3 PF01757.17 EGC34110.1 - 9.5e-05 21.3 27.3 0.0011 17.9 7.5 2.3 1 1 1 2 2 2 2 Acyltransferase family FNIP PF05725.7 EGC34111.1 - 2.5e-59 196.9 95.8 4.8e-09 36.0 0.4 14.4 8 3 8 16 16 16 15 FNIP Repeat Mucin PF01456.12 EGC34113.1 - 0.00011 21.9 1.5 0.00015 21.5 1.0 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 EGC34113.1 - 0.17 9.8 6.4 0.24 9.3 4.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 p450 PF00067.17 EGC34114.1 - 9.6e-19 67.2 0.0 1e-18 67.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 ECH PF00378.15 EGC34115.1 - 4.9e-45 153.5 0.0 6.1e-45 153.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family Peptidase_S49 PF01343.13 EGC34115.1 - 0.012 15.4 0.0 5.1 6.8 0.0 2.4 2 0 0 2 2 2 0 Peptidase family S49 Patatin PF01734.17 EGC34116.1 - 0.0058 16.5 0.0 0.032 14.1 0.0 2.1 1 1 0 1 1 1 1 Patatin-like phospholipase Patatin PF01734.17 EGC34117.1 - 2.9e-22 79.5 0.0 4.8e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 Patatin-like phospholipase MIF4G PF02854.14 EGC34118.1 - 2.3e-26 92.4 1.6 2.3e-26 92.4 1.1 2.5 3 0 0 3 3 3 1 MIF4G domain MA3 PF02847.12 EGC34118.1 - 7.5e-23 80.3 0.7 2.1e-22 78.9 0.5 1.8 1 0 0 1 1 1 1 MA3 domain TetR_C_8 PF14278.1 EGC34118.1 - 0.01 16.1 0.2 0.071 13.5 0.0 2.6 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region CDC45 PF02724.9 EGC34118.1 - 0.79 7.6 23.8 0.36 8.8 6.2 2.3 2 0 0 2 2 2 0 CDC45-like protein FAM176 PF14851.1 EGC34118.1 - 6.8 6.3 9.1 1.1 8.9 0.3 2.4 2 0 0 2 2 2 0 FAM176 family SSP160 PF06933.6 EGC34118.1 - 9.2 4.1 8.2 15 3.4 5.7 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ammonium_transp PF00909.16 EGC34119.1 - 2.9e-100 335.5 28.5 3.3e-100 335.3 19.8 1.0 1 0 0 1 1 1 1 Ammonium Transporter Family DLH PF01738.13 EGC34120.1 - 1e-35 123.0 0.0 1.1e-35 122.8 0.0 1.0 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGC34120.1 - 1.6e-08 34.4 0.0 2.2e-08 33.9 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC34120.1 - 4e-06 26.8 0.0 0.00011 22.2 0.0 2.0 1 1 1 2 2 2 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGC34120.1 - 0.00073 19.3 0.1 0.0025 17.5 0.0 1.7 1 1 0 1 1 1 1 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EGC34120.1 - 0.0024 17.1 0.6 0.27 10.4 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGC34120.1 - 0.0027 17.1 0.0 0.0036 16.7 0.0 1.1 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EGC34120.1 - 0.0089 15.6 0.1 0.18 11.3 0.1 2.5 1 1 1 2 2 2 1 alpha/beta hydrolase fold Chlorophyllase PF07224.6 EGC34120.1 - 0.017 13.9 0.0 0.11 11.2 0.0 2.0 1 1 0 1 1 1 0 Chlorophyllase Chlorophyllase2 PF12740.2 EGC34120.1 - 0.042 12.7 0.0 0.14 11.0 0.0 1.8 1 1 0 2 2 2 0 Chlorophyllase enzyme Esterase PF00756.15 EGC34120.1 - 0.053 12.9 0.0 0.1 12.0 0.0 1.6 2 0 0 2 2 2 0 Putative esterase ER PF01133.12 EGC34122.1 - 0.0068 16.0 0.4 0.014 15.0 0.3 1.5 1 0 0 1 1 1 1 Enhancer of rudimentary DUF2670 PF10875.3 EGC34122.1 - 0.023 14.7 0.2 0.033 14.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2670) DUF521 PF04412.8 EGC34122.1 - 0.14 10.7 0.0 0.17 10.4 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF521) F-box-like PF12937.2 EGC34123.1 - 0.0011 18.6 0.0 0.0038 16.9 0.0 1.9 1 0 0 1 1 1 1 F-box-like DUF1914 PF08932.5 EGC34123.1 - 0.059 13.3 0.2 0.11 12.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1914) COesterase PF00135.23 EGC34124.1 - 6.8e-107 358.3 0.0 1.2e-70 238.7 0.0 2.0 1 1 1 2 2 2 2 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC34124.1 - 0.0031 17.1 0.0 0.0058 16.2 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC34124.1 - 0.032 13.4 0.0 0.051 12.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family COesterase PF00135.23 EGC34125.1 - 4.5e-124 415.0 0.0 6.5e-124 414.5 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC34125.1 - 0.0018 17.8 0.1 0.012 15.1 0.1 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC34125.1 - 0.12 11.6 0.0 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family FSH1 PF03959.8 EGC34127.1 - 1.2e-50 171.8 0.8 6.3e-37 127.0 0.1 2.6 2 1 0 2 2 2 2 Serine hydrolase (FSH1) Abhydrolase_5 PF12695.2 EGC34127.1 - 2.1e-05 24.2 0.0 4e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC34127.1 - 5.6e-05 23.1 0.0 0.0019 18.1 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34127.1 - 0.0035 16.9 0.1 0.021 14.3 0.0 2.1 2 0 0 2 2 2 1 alpha/beta hydrolase fold BAAT_C PF08840.6 EGC34127.1 - 0.027 14.1 0.0 0.48 10.0 0.0 2.2 2 0 0 2 2 2 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_2 PF02230.11 EGC34127.1 - 0.063 12.7 0.6 11 5.3 0.0 2.4 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase DLH PF01738.13 EGC34127.1 - 0.14 11.3 0.0 6.6 5.9 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Complex1_LYR PF05347.10 EGC34128.1 - 2.6e-11 43.1 0.2 3.1e-11 42.8 0.1 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC34128.1 - 7.3e-11 42.1 0.1 8.5e-11 41.9 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like Dpy19 PF10034.4 EGC34128.1 - 0.12 10.5 0.0 0.14 10.2 0.0 1.0 1 0 0 1 1 1 0 Q-cell neuroblast polarisation C2 PF00168.25 EGC34129.1 - 7.1e-25 86.6 0.0 1.2e-24 85.9 0.0 1.4 1 0 0 1 1 1 1 C2 domain Racemase_4 PF13615.1 EGC34130.1 - 2.5e-25 88.6 0.3 8.6e-25 86.9 0.0 2.1 2 0 0 2 2 2 1 Putative alanine racemase MCM_bind PF09739.4 EGC34130.1 - 4e-25 87.7 1.9 4e-25 87.7 1.3 2.5 2 0 0 2 2 2 1 Mini-chromosome maintenance replisome factor CRAL_TRIO PF00650.15 EGC34131.1 - 4.6e-32 110.7 0.2 6.3e-32 110.2 0.1 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGC34131.1 - 4.8e-09 36.2 1.2 4.8e-09 36.2 0.9 2.2 2 0 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGC34131.1 - 6.3e-06 26.1 0.4 9.1e-06 25.6 0.3 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain Pex24p PF06398.6 EGC34132.1 - 0.00061 18.6 6.2 0.00071 18.4 4.3 1.1 1 0 0 1 1 1 1 Integral peroxisomal membrane peroxin DUF1279 PF06916.8 EGC34132.1 - 0.013 15.7 0.6 0.093 13.0 0.1 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF1279) DUF1512 PF07431.7 EGC34132.1 - 1.9 7.1 6.9 0.13 10.9 0.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1512) AA_permease_2 PF13520.1 EGC34133.1 - 0.15 10.6 7.4 0.11 11.0 3.7 1.7 1 1 0 1 1 1 0 Amino acid permease DUF3357 PF11837.3 EGC34133.1 - 0.21 11.4 6.0 1.5 8.7 0.8 2.9 1 1 1 3 3 3 0 Domain of unknown function (DUF3357) LRRNT_2 PF08263.7 EGC34133.1 - 2 8.4 18.2 7.6 6.5 0.3 4.3 4 0 0 4 4 4 0 Leucine rich repeat N-terminal domain NAGLU_N PF12971.2 EGC34133.1 - 4.4 7.0 12.8 0.25 11.0 0.5 2.6 2 1 1 3 3 3 0 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Clat_adaptor_s PF01217.15 EGC34134.1 - 1.9e-14 53.6 2.3 2.3e-14 53.3 1.6 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Transposase_23 PF03017.9 EGC34134.1 - 0.0011 18.3 0.0 0.057 12.9 0.0 2.3 2 0 0 2 2 2 1 TNP1/EN/SPM transposase EssA PF10661.4 EGC34134.1 - 0.026 14.1 0.8 2.7 7.6 0.1 2.1 1 1 1 2 2 2 0 WXG100 protein secretion system (Wss), protein EssA Ribosomal_S5 PF00333.15 EGC34135.1 - 3.2e-06 26.7 2.2 4.1e-06 26.4 0.2 2.1 2 0 0 2 2 2 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGC34135.1 - 0.23 10.7 0.0 0.99 8.7 0.0 2.1 2 0 0 2 2 2 0 Ribosomal protein S5, C-terminal domain Xpo1 PF08389.7 EGC34136.1 - 7.6e-17 61.5 0.3 7.6e-17 61.5 0.2 6.7 5 2 2 7 7 7 2 Exportin 1-like protein TFCD_C PF12612.3 EGC34136.1 - 0.00038 19.9 0.4 0.0021 17.4 0.0 2.6 2 0 0 2 2 2 1 Tubulin folding cofactor D C terminal DUF1722 PF08349.6 EGC34136.1 - 0.0071 16.2 0.2 0.11 12.3 0.0 2.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1722) DUF4042 PF13251.1 EGC34136.1 - 0.0097 15.3 0.5 0.3 10.5 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4042) Condensin2nSMC PF12422.3 EGC34136.1 - 0.062 13.0 3.5 0.21 11.3 0.2 3.4 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit C2 PF00168.25 EGC34138.1 - 1.2e-17 63.5 0.1 2.2e-17 62.6 0.0 1.5 1 0 0 1 1 1 1 C2 domain GCN5L1 PF06320.8 EGC34139.1 - 0.016 15.0 0.2 0.016 15.0 0.2 3.7 4 0 0 4 4 4 0 GCN5-like protein 1 (GCN5L1) Peroxin-13_N PF04088.8 EGC34139.1 - 0.13 12.2 0.2 0.13 12.2 0.1 3.2 2 1 0 2 2 2 0 Peroxin 13, N-terminal region DUF1212 PF06738.7 EGC34139.1 - 0.32 10.4 0.5 0.99 8.8 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1212) Mitofilin PF09731.4 EGC34140.1 - 0.12 10.9 35.2 0.14 10.7 20.9 2.1 2 0 0 2 2 2 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 EGC34140.1 - 1.9 6.8 58.2 0.18 10.2 36.7 1.8 2 0 0 2 2 2 0 Microtubule-binding protein MIP-T3 Ycf1 PF05758.7 EGC34140.1 - 2.8 5.5 29.3 0.13 9.9 16.8 1.5 2 0 0 2 2 2 0 Ycf1 zf-H2C2_2 PF13465.1 EGC34141.1 - 3.1e-05 24.0 2.1 3.1e-05 24.0 1.5 5.2 6 1 1 7 7 7 1 Zinc-finger double domain zf-C2H2 PF00096.21 EGC34141.1 - 0.003 17.8 19.6 0.17 12.2 0.7 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type Glyco_hydro_25 PF01183.15 EGC34142.1 - 1.4e-15 57.6 0.0 1.6e-15 57.4 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 WD40 PF00400.27 EGC34143.1 - 4.7e-20 70.6 9.0 3.1e-09 36.3 0.3 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Ded_cyto PF06920.8 EGC34144.1 - 2.1e-53 180.2 4.5 2.1e-53 180.2 3.1 1.9 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC34144.1 - 5.1e-45 153.3 5.1 8.4e-45 152.6 1.4 2.7 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Ipi1_N PF12333.3 EGC34144.1 - 0.026 14.4 0.0 0.16 11.9 0.0 2.5 1 0 0 1 1 1 0 Rix1 complex component involved in 60S ribosome maturation Reticulon PF02453.12 EGC34145.1 - 1.2e-32 112.7 9.9 1.2e-32 112.7 6.8 1.9 2 1 0 2 2 2 1 Reticulon Apolipoprotein PF01442.13 EGC34145.1 - 8.4e-06 25.4 2.1 1.3e-05 24.8 1.4 1.2 1 0 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 EGC34145.1 - 0.00012 19.7 7.7 0.00021 18.9 5.4 1.3 1 0 0 1 1 1 1 Prominin Baculo_PEP_C PF04513.7 EGC34145.1 - 0.0015 18.3 5.8 0.0037 17.0 2.1 2.4 2 0 0 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus YtxH PF12732.2 EGC34145.1 - 0.0028 17.9 12.8 0.0039 17.5 4.2 2.4 1 1 1 2 2 2 2 YtxH-like protein APG17 PF04108.7 EGC34145.1 - 0.0038 16.1 7.0 0.0039 16.0 3.8 1.7 2 0 0 2 2 2 1 Autophagy protein Apg17 Reo_sigmaC PF04582.7 EGC34145.1 - 0.0068 15.6 1.0 0.0098 15.0 0.7 1.2 1 0 0 1 1 1 1 Reovirus sigma C capsid protein WEMBL PF05701.6 EGC34145.1 - 0.0071 14.8 9.5 0.009 14.5 6.6 1.1 1 0 0 1 1 1 1 Weak chloroplast movement under blue light DUF883 PF05957.8 EGC34145.1 - 0.0099 16.2 3.6 0.075 13.4 2.6 2.1 1 1 0 1 1 1 1 Bacterial protein of unknown function (DUF883) ISG65-75 PF11727.3 EGC34145.1 - 0.01 14.9 6.2 0.017 14.1 4.3 1.3 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2317 PF10079.4 EGC34145.1 - 0.013 14.1 5.5 0.02 13.5 3.8 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2317) Gp-FAR-1 PF05823.7 EGC34145.1 - 0.026 14.5 1.8 0.026 14.5 1.2 1.9 2 0 0 2 2 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) DUF1664 PF07889.7 EGC34145.1 - 0.034 13.9 10.7 0.025 14.3 5.0 2.6 2 1 0 2 2 1 0 Protein of unknown function (DUF1664) RasGAP PF00616.14 EGC34145.1 - 0.037 13.7 2.3 0.044 13.4 0.7 1.8 2 0 0 2 2 1 0 GTPase-activator protein for Ras-like GTPase DUF1043 PF06295.7 EGC34145.1 - 0.052 13.1 1.1 0.14 11.7 0.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1043) DUF2746 PF10874.3 EGC34145.1 - 0.052 13.7 2.4 0.16 12.1 1.7 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2746) Bacillus_HBL PF05791.6 EGC34145.1 - 0.057 12.7 6.9 0.17 11.2 4.8 1.7 1 0 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) Baculo_p24 PF05073.7 EGC34145.1 - 0.061 12.8 5.3 0.18 11.3 3.7 1.7 1 0 0 1 1 1 0 Baculovirus P24 capsid protein Syntaxin PF00804.20 EGC34145.1 - 0.061 13.4 15.5 0.4 10.8 8.1 3.0 2 1 0 2 2 1 0 Syntaxin DUF2518 PF10726.4 EGC34145.1 - 0.071 12.6 1.4 0.14 11.6 1.0 1.6 1 0 0 1 1 1 0 Protein of function (DUF2518) CheX PF13690.1 EGC34145.1 - 0.08 12.8 1.1 3.4 7.5 0.0 2.5 2 0 0 2 2 2 0 Chemotaxis phosphatase CheX ApoO PF09769.4 EGC34145.1 - 0.11 12.2 1.1 0.27 10.9 0.7 1.7 1 1 0 1 1 1 0 Apolipoprotein O DUF3584 PF12128.3 EGC34145.1 - 0.12 9.7 3.8 0.15 9.3 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EGC34145.1 - 0.12 10.8 6.1 0.18 10.2 4.2 1.3 1 0 0 1 1 1 0 AAA domain Fmp27_WPPW PF10359.4 EGC34145.1 - 0.12 10.8 2.2 0.16 10.3 1.5 1.1 1 0 0 1 1 1 0 RNA pol II promoter Fmp27 protein domain MCPsignal PF00015.16 EGC34145.1 - 0.12 11.8 12.9 0.082 12.4 5.1 2.2 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain WXG100 PF06013.7 EGC34145.1 - 0.15 12.0 0.2 0.33 10.9 0.1 1.6 1 0 0 1 1 1 0 Proteins of 100 residues with WXG MIS13 PF08202.6 EGC34145.1 - 0.15 11.0 3.6 0.28 10.2 2.5 1.5 1 0 0 1 1 1 0 Mis12-Mtw1 protein family CK2S PF15011.1 EGC34145.1 - 0.16 11.7 1.9 2.5 7.8 1.0 2.7 2 1 0 2 2 2 0 Casein Kinase 2 substrate Z1 PF10593.4 EGC34145.1 - 0.18 10.9 1.5 0.28 10.3 1.0 1.3 1 0 0 1 1 1 0 Z1 domain HisKA_3 PF07730.8 EGC34145.1 - 0.19 12.0 0.1 4.5 7.6 0.1 2.9 4 0 0 4 4 2 0 Histidine kinase Transposase_22 PF02994.9 EGC34145.1 - 0.2 10.1 9.5 0.33 9.3 6.6 1.2 1 0 0 1 1 1 0 L1 transposable element DUF2205 PF10224.4 EGC34145.1 - 0.25 10.9 6.3 0.53 9.8 4.4 1.6 1 0 0 1 1 1 0 Predicted coiled-coil protein (DUF2205) ApoLp-III PF07464.6 EGC34145.1 - 0.28 11.1 11.5 0.38 10.7 7.3 1.7 2 0 0 2 2 1 0 Apolipophorin-III precursor (apoLp-III) HsbA PF12296.3 EGC34145.1 - 0.29 10.9 5.5 0.097 12.5 1.2 2.2 2 1 0 2 2 1 0 Hydrophobic surface binding protein A DUF2959 PF11172.3 EGC34145.1 - 0.36 10.5 7.5 0.59 9.8 5.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2959) GvpL_GvpF PF06386.6 EGC34145.1 - 0.45 10.0 4.2 0.63 9.5 2.9 1.2 1 0 0 1 1 1 0 Gas vesicle synthesis protein GvpL/GvpF DUF1451 PF07295.6 EGC34145.1 - 0.47 10.2 4.6 0.88 9.3 2.9 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF1451) Spc7 PF08317.6 EGC34145.1 - 0.51 8.9 7.0 0.88 8.1 4.8 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein LPP PF04728.8 EGC34145.1 - 0.54 10.0 2.9 1.6 8.5 0.4 2.6 1 1 1 2 2 2 0 Lipoprotein leucine-zipper ACCA PF03255.9 EGC34145.1 - 0.56 9.7 2.8 1.1 8.7 2.0 1.5 1 0 0 1 1 1 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit TMP_2 PF06791.8 EGC34145.1 - 0.69 9.4 3.9 0.42 10.1 0.6 1.8 1 1 1 2 2 2 0 Prophage tail length tape measure protein COG5 PF10392.4 EGC34145.1 - 0.76 9.7 3.3 2.3 8.2 2.3 1.9 1 1 0 1 1 1 0 Golgi transport complex subunit 5 FH2 PF02181.18 EGC34145.1 - 0.78 8.5 7.0 1.2 7.9 4.8 1.2 1 0 0 1 1 1 0 Formin Homology 2 Domain Spectrin PF00435.16 EGC34145.1 - 0.93 9.8 4.9 2.2 8.6 3.4 1.7 1 0 0 1 1 1 0 Spectrin repeat Allexi_40kDa PF05549.6 EGC34145.1 - 1.1 8.5 3.3 1.9 7.6 2.3 1.3 1 0 0 1 1 1 0 Allexivirus 40kDa protein DUF2352 PF09817.4 EGC34145.1 - 1.1 7.3 6.8 1.6 6.8 4.7 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2352) Atg14 PF10186.4 EGC34145.1 - 1.2 8.0 4.2 2.2 7.1 2.9 1.4 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 RmuC PF02646.11 EGC34145.1 - 1.2 7.9 7.1 0.91 8.2 3.5 1.8 2 0 0 2 2 2 0 RmuC family NPV_P10 PF05531.7 EGC34145.1 - 1.3 9.3 14.0 16 5.8 7.0 3.3 2 1 0 2 2 2 0 Nucleopolyhedrovirus P10 protein Laminin_II PF06009.7 EGC34145.1 - 1.3 8.7 13.1 1.7 8.3 7.2 2.4 2 1 0 2 2 2 0 Laminin Domain II V-SNARE PF05008.10 EGC34145.1 - 1.4 9.1 9.9 0.78 9.9 1.0 2.8 3 1 0 3 3 2 0 Vesicle transport v-SNARE protein N-terminus COG2 PF06148.6 EGC34145.1 - 1.4 8.7 10.1 2.2 8.1 2.7 2.4 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF2203 PF09969.4 EGC34145.1 - 1.5 9.0 4.0 3.4 7.9 2.8 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) Fzo_mitofusin PF04799.8 EGC34145.1 - 1.5 8.1 6.1 1.6 8.1 2.1 2.2 1 1 1 2 2 2 0 fzo-like conserved region Syntaxin-6_N PF09177.6 EGC34145.1 - 1.5 9.2 9.0 9.3 6.7 5.6 2.5 2 1 0 2 2 1 0 Syntaxin 6, N-terminal PRD PF00874.15 EGC34145.1 - 1.6 8.9 6.1 0.69 10.0 0.1 2.9 4 0 0 4 4 2 0 PRD domain DUF848 PF05852.6 EGC34145.1 - 2 8.2 7.1 3.9 7.3 4.3 2.0 1 1 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) Mnd1 PF03962.10 EGC34145.1 - 2.4 7.8 9.0 5.2 6.6 6.2 1.6 1 0 0 1 1 1 0 Mnd1 family FlaC_arch PF05377.6 EGC34145.1 - 2.6 7.9 22.4 0.52 10.2 2.2 4.1 2 1 2 4 4 4 0 Flagella accessory protein C (FlaC) MCP_N PF05581.7 EGC34145.1 - 2.9 8.0 12.3 2.7 8.1 1.8 3.3 2 1 2 4 4 3 0 Vibrio chemotaxis protein N terminus DASH_Duo1 PF08651.5 EGC34145.1 - 4 7.0 7.0 6.1 6.5 0.4 3.3 2 1 2 4 4 3 0 DASH complex subunit Duo1 DUF948 PF06103.6 EGC34145.1 - 5.6 6.9 13.0 8.2 6.3 5.3 3.3 2 1 1 3 3 3 0 Bacterial protein of unknown function (DUF948) Phage_GPO PF05929.6 EGC34145.1 - 5.7 6.0 7.7 14 4.8 5.3 1.6 1 0 0 1 1 1 0 Phage capsid scaffolding protein (GPO) serine peptidase Seryl_tRNA_N PF02403.17 EGC34145.1 - 6 6.9 12.6 29 4.7 8.7 2.2 1 1 0 1 1 1 0 Seryl-tRNA synthetase N-terminal domain Phasin PF05597.6 EGC34145.1 - 7.6 6.3 12.4 11 5.8 4.0 2.5 1 1 1 2 2 2 0 Poly(hydroxyalcanoate) granule associated protein (phasin) GP41 PF00517.12 EGC34145.1 - 7.6 6.0 10.7 0.16 11.5 0.9 2.7 3 1 0 3 3 2 0 Retroviral envelope protein DUF677 PF05055.7 EGC34145.1 - 8.4 4.9 14.1 23 3.5 9.8 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF677) Fib_alpha PF08702.5 EGC34145.1 - 8.4 6.5 9.8 9.8 6.2 5.4 2.2 2 1 0 2 2 1 0 Fibrinogen alpha/beta chain family HlyIII PF03006.15 EGC34146.1 - 7.3e-47 159.6 23.1 9.2e-47 159.2 16.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Aa_trans PF01490.13 EGC34147.1 - 7.9e-56 189.2 32.0 9.8e-56 188.9 22.2 1.0 1 0 0 1 1 1 1 Transmembrane amino acid transporter protein PIP5K PF01504.13 EGC34148.1 - 9.8e-23 80.5 11.3 7.2e-19 67.8 4.8 2.4 1 1 1 2 2 2 2 Phosphatidylinositol-4-phosphate 5-Kinase Mucin PF01456.12 EGC34149.1 - 0.0057 16.4 7.0 0.01 15.6 4.9 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 EGC34149.1 - 0.52 10.0 7.0 1.6 8.4 4.8 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) 7TM_GPCR_Srd PF10317.4 EGC34149.1 - 0.76 8.7 9.2 1.5 7.7 6.4 1.6 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd HATPase_c PF02518.21 EGC34150.1 - 5.4e-29 100.1 0.1 1.4e-28 98.7 0.1 1.8 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase CHASE PF03924.8 EGC34150.1 - 7.1e-29 100.4 0.0 1.5e-28 99.3 0.0 1.5 1 0 0 1 1 1 1 CHASE domain Response_reg PF00072.19 EGC34150.1 - 1.3e-21 76.6 0.1 8e-21 74.1 0.0 2.2 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGC34150.1 - 4.1e-21 74.7 0.1 8.6e-21 73.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_3 PF08447.6 EGC34150.1 - 4.1e-07 29.9 0.0 1e-06 28.7 0.0 1.6 1 0 0 1 1 1 1 PAS fold TIG PF01833.19 EGC34151.1 - 0.09 12.7 22.0 0.05 13.6 0.7 4.7 5 0 0 5 5 5 0 IPT/TIG domain EGF_2 PF07974.8 EGC34151.1 - 0.25 11.5 4.8 0.71 10.0 3.3 1.8 1 0 0 1 1 1 0 EGF-like domain DUF2428 PF10350.4 EGC34153.1 - 2.9e-59 200.1 0.4 9.6e-59 198.4 0.1 2.1 2 0 0 2 2 2 1 Putative death-receptor fusion protein (DUF2428) HEAT PF02985.17 EGC34153.1 - 0.00019 21.2 0.1 0.21 11.7 0.0 4.8 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGC34153.1 - 0.028 14.6 0.1 18 5.7 0.0 4.0 4 0 0 4 4 4 0 HEAT repeats Kelch_6 PF13964.1 EGC34154.1 - 2.8e-11 43.0 5.6 2.9e-05 24.0 0.1 4.7 3 1 1 4 4 4 2 Kelch motif Kelch_4 PF13418.1 EGC34154.1 - 3.6e-07 29.8 2.3 0.088 12.5 0.0 4.0 4 0 0 4 4 4 2 Galactose oxidase, central domain zf-C3HC4 PF00097.20 EGC34154.1 - 6.7e-07 28.8 10.9 6.7e-07 28.8 7.6 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Kelch_1 PF01344.20 EGC34154.1 - 1.7e-06 27.4 11.5 0.0099 15.4 0.1 5.5 6 0 0 6 6 6 2 Kelch motif Kelch_5 PF13854.1 EGC34154.1 - 5.4e-06 26.2 7.9 0.12 12.4 0.0 4.2 5 0 0 5 5 5 2 Kelch motif Kelch_2 PF07646.10 EGC34154.1 - 1.4e-05 24.6 1.4 0.56 10.0 0.0 4.4 4 0 0 4 4 4 2 Kelch motif zf-B_box PF00643.19 EGC34154.1 - 3e-05 23.7 6.9 3e-05 23.7 4.8 3.1 3 0 0 3 3 2 1 B-box zinc finger zf-C3HC4_4 PF15227.1 EGC34154.1 - 5.2e-05 23.0 10.1 5.2e-05 23.0 7.0 3.0 3 0 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGC34154.1 - 0.00031 20.5 8.7 0.00031 20.5 6.0 2.7 2 0 0 2 2 2 1 Ring finger domain Kelch_3 PF13415.1 EGC34154.1 - 0.00032 20.7 1.0 0.018 15.2 0.1 3.7 4 0 0 4 4 4 1 Galactose oxidase, central domain zf-C3HC4_2 PF13923.1 EGC34154.1 - 0.00041 20.3 11.3 0.00041 20.3 7.8 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-MIZ PF02891.15 EGC34154.1 - 0.00096 18.6 9.7 0.0027 17.1 6.7 1.8 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EGC34154.1 - 0.003 17.2 9.2 0.003 17.2 6.4 2.6 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_6 PF14835.1 EGC34154.1 - 0.013 15.2 4.4 0.013 15.2 3.1 2.4 2 0 0 2 2 2 0 zf-RING of BARD1-type protein OrfB_Zn_ribbon PF07282.6 EGC34155.1 - 1.9e-05 24.2 0.2 0.078 12.6 0.0 2.2 2 0 0 2 2 2 2 Putative transposase DNA-binding domain RNA_pol_Rpb1_1 PF04997.7 EGC34156.1 - 6.3e-22 78.2 0.1 7.3e-22 78.0 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 WD40 PF00400.27 EGC34158.1 - 7.6e-32 108.0 23.2 8.7e-06 25.4 0.3 7.7 7 1 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGC34158.1 - 2.2e-09 36.8 0.7 4.3e-09 35.9 0.1 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC34158.1 - 8.1e-06 25.3 2.4 8.9e-06 25.2 0.4 2.1 2 0 0 2 2 2 1 F-box domain TATR PF03430.8 EGC34159.1 - 7.4 5.0 36.9 8.9 4.8 25.6 1.2 1 0 0 1 1 1 0 Trans-activating transcriptional regulator DUF2746 PF10874.3 EGC34161.1 - 4.8 7.4 6.3 1.4 9.1 0.2 3.2 4 0 0 4 4 4 0 Protein of unknown function (DUF2746) zf-C2H2 PF00096.21 EGC34162.1 - 3.8e-24 83.5 74.4 0.00012 22.2 0.6 9.5 9 0 0 9 9 9 9 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGC34162.1 - 2.3e-17 61.9 67.4 0.0029 17.8 0.4 9.5 9 0 0 9 9 9 9 C2H2-type zinc finger zf-H2C2_2 PF13465.1 EGC34162.1 - 1.1e-10 41.1 76.5 1.4e-07 31.4 0.8 10.0 11 0 0 11 11 11 5 Zinc-finger double domain zf-C2H2_6 PF13912.1 EGC34162.1 - 1.4 8.9 32.9 0.038 13.8 3.8 6.4 6 0 0 6 6 6 0 C2H2-type zinc finger RCC1 PF00415.13 EGC34164.1 - 6.8e-27 93.4 2.1 2.3e-07 30.9 0.0 8.4 7 2 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC34164.1 - 3.7e-21 74.1 11.2 0.00049 19.6 0.0 7.9 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 EGC34164.1 - 0.38 10.5 3.6 9.1 6.1 0.1 3.5 2 1 1 3 3 3 0 Galactose oxidase, central domain CTP_synth_N PF06418.9 EGC34165.1 - 1.4e-125 417.8 0.1 3e-125 416.8 0.1 1.5 1 0 0 1 1 1 1 CTP synthase N-terminus GATase PF00117.23 EGC34165.1 - 1.3e-54 184.6 0.0 2e-54 183.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGC34165.1 - 0.00013 21.4 0.2 0.00063 19.2 0.1 2.2 1 1 1 2 2 2 1 Peptidase C26 CbiA PF01656.18 EGC34165.1 - 0.017 14.5 0.0 0.029 13.7 0.0 1.4 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain FAD_binding_2 PF00890.19 EGC34166.1 - 2.2e-123 412.1 4.6 2.9e-123 411.7 3.2 1.2 1 0 0 1 1 1 1 FAD binding domain Succ_DH_flav_C PF02910.15 EGC34166.1 - 3e-46 156.4 1.9 5.5e-46 155.5 1.3 1.5 1 0 0 1 1 1 1 Fumarate reductase flavoprotein C-term Pyr_redox_2 PF07992.9 EGC34166.1 - 9.9e-08 32.0 1.1 2.1e-05 24.5 0.7 2.8 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGC34166.1 - 1.5e-07 30.6 1.1 2e-06 26.9 0.7 2.2 1 1 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGC34166.1 - 1.7e-05 24.0 0.2 0.01 14.9 0.0 3.2 3 0 0 3 3 3 1 Thi4 family GIDA PF01134.17 EGC34166.1 - 9.9e-05 21.3 3.1 0.049 12.4 1.6 2.4 2 0 0 2 2 2 2 Glucose inhibited division protein A FAD_binding_3 PF01494.14 EGC34166.1 - 0.0045 16.1 0.2 0.0083 15.2 0.2 1.4 1 0 0 1 1 1 1 FAD binding domain HI0933_like PF03486.9 EGC34166.1 - 0.03 12.8 0.0 0.16 10.4 0.0 2.1 2 0 0 2 2 2 0 HI0933-like protein Dor1 PF04124.7 EGC34166.1 - 0.073 11.5 0.6 0.11 10.9 0.4 1.2 1 0 0 1 1 1 0 Dor1-like family Chromosome_seg PF13889.1 EGC34167.1 - 1.8e-23 82.1 3.4 4.4e-23 80.9 2.3 1.7 1 0 0 1 1 1 1 Chromosome segregation during meiosis DUF4210 PF13915.1 EGC34167.1 - 5.2e-22 77.9 0.0 2.7e-21 75.6 0.0 2.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4210) LRR_6 PF13516.1 EGC34168.1 - 4.4e-09 35.4 51.1 0.026 14.5 0.1 13.0 11 1 2 13 13 13 6 Leucine Rich repeat F-box PF00646.28 EGC34168.1 - 0.015 14.9 1.0 4.8 6.9 0.1 2.8 2 0 0 2 2 2 0 F-box domain F-box-like PF12937.2 EGC34168.1 - 0.022 14.5 0.4 5.3 6.8 0.1 2.8 2 0 0 2 2 2 0 F-box-like LRR_7 PF13504.1 EGC34168.1 - 0.029 14.5 22.9 37 5.1 0.0 10.6 10 0 0 10 10 10 0 Leucine rich repeat UcrQ PF02939.11 EGC34169.1 - 2.2e-12 46.5 0.5 2.3e-12 46.5 0.4 1.0 1 0 0 1 1 1 1 UcrQ family DUF2741 PF10890.3 EGC34169.1 - 4.9e-07 29.7 0.1 5e-07 29.7 0.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF2741) Snf7 PF03357.16 EGC34170.1 - 3.9e-33 114.2 16.8 4.8e-33 113.9 11.6 1.0 1 0 0 1 1 1 1 Snf7 Planc_extracel PF07595.7 EGC34170.1 - 0.068 12.8 0.8 0.15 11.8 0.5 1.6 1 0 0 1 1 1 0 Planctomycete extracellular DUF2840 PF11000.3 EGC34170.1 - 0.096 12.2 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2840) Snurportin1 PF11538.3 EGC34170.1 - 8.2 6.2 6.5 0.4 10.4 0.6 1.9 2 0 0 2 2 2 0 Snurportin1 VCBS PF13517.1 EGC34171.1 - 4.9e-08 33.2 1.1 0.18 12.2 0.0 3.8 3 0 0 3 3 3 3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGC34171.1 - 1.1e-06 28.0 4.7 0.049 13.3 0.0 3.4 3 0 0 3 3 3 3 FG-GAP repeat Cyt-b5 PF00173.23 EGC34173.1 - 1.8e-22 78.9 0.1 2.4e-22 78.4 0.1 1.2 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain EF-hand_5 PF13202.1 EGC34173.1 - 0.011 15.0 1.3 0.013 14.8 0.1 1.7 2 0 0 2 2 2 0 EF hand EF-hand_1 PF00036.27 EGC34173.1 - 0.1 11.9 0.1 0.28 10.5 0.0 1.8 1 0 0 1 1 1 0 EF hand Complex1_LYR_2 PF13233.1 EGC34174.1 - 5.5e-05 23.5 10.1 0.00018 21.9 7.0 1.9 1 1 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGC34174.1 - 5.7e-05 22.8 0.1 5.7e-05 22.8 0.1 2.5 3 1 0 3 3 3 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC34174.1 - 0.00027 21.1 0.1 0.00027 21.1 0.0 2.1 2 1 0 2 2 2 1 Complex1_LYR-like Hypoth_Ymh PF09509.5 EGC34174.1 - 0.11 12.0 2.3 0.16 11.5 1.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) Metal_resist PF13801.1 EGC34174.1 - 0.14 12.1 0.1 0.21 11.6 0.0 1.2 1 0 0 1 1 1 0 Heavy-metal resistance DUF4111 PF13427.1 EGC34174.1 - 0.18 11.6 3.0 0.11 12.3 0.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4111) RHH_3 PF12651.2 EGC34174.1 - 0.2 11.4 2.0 1.5 8.6 0.7 2.3 2 0 0 2 2 2 0 Ribbon-helix-helix domain GIDA_assoc_3 PF13932.1 EGC34174.1 - 0.34 10.9 3.3 2 8.5 0.1 2.3 1 1 1 2 2 2 0 GidA associated domain 3 Iron_traffic PF04362.9 EGC34174.1 - 1.8 8.0 9.7 0.5 9.8 1.1 2.4 2 1 0 2 2 2 0 Bacterial Fe(2+) trafficking RRM_6 PF14259.1 EGC34177.1 - 0.11 12.5 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) L_biotic_typeA PF04604.8 EGC34177.1 - 0.12 12.0 0.0 0.15 11.7 0.0 1.3 1 0 0 1 1 1 0 Type-A lantibiotic zf-ribbon_3 PF13248.1 EGC34178.1 - 0.11 11.6 0.1 0.19 10.9 0.0 1.3 1 0 0 1 1 1 0 zinc-ribbon domain GATA PF00320.22 EGC34178.1 - 0.14 11.5 0.0 0.17 11.2 0.0 1.1 1 0 0 1 1 1 0 GATA zinc finger Gcd10p PF04189.8 EGC34179.1 - 6.7e-74 248.7 8.6 6.7e-74 248.7 5.9 2.5 2 1 1 3 3 3 1 Gcd10p family Adeno_E1A PF02703.9 EGC34180.1 - 0.042 13.2 0.3 0.087 12.2 0.0 1.6 1 1 0 1 1 1 0 Early E1A protein DUF1675 PF07897.6 EGC34180.1 - 4 7.2 12.6 4.6 7.0 8.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) SprA-related PF12118.3 EGC34180.1 - 5.9 6.1 16.8 6.9 5.8 11.7 1.2 1 0 0 1 1 1 0 SprA-related family PHB_depo_C PF06850.6 EGC34181.1 - 0.023 13.9 0.2 0.033 13.3 0.1 1.4 1 1 0 1 1 1 0 PHB de-polymerase C-terminus Stn1 PF10451.4 EGC34181.1 - 0.041 12.7 0.9 0.051 12.4 0.3 1.5 1 1 0 1 1 1 0 Telomere regulation protein Stn1 Ribosomal_L13 PF00572.13 EGC34182.1 - 2.2e-26 92.3 0.0 8.7e-26 90.4 0.0 1.9 2 0 0 2 2 2 1 Ribosomal protein L13 TP53IP5 PF15331.1 EGC34182.1 - 0.0056 16.6 0.1 0.01 15.7 0.1 1.4 1 0 0 1 1 1 1 Cellular tumour antigen p53-inducible 5 Malate_synthase PF01274.17 EGC34183.1 - 4e-204 678.4 0.0 4.5e-204 678.2 0.0 1.0 1 0 0 1 1 1 1 Malate synthase PDZ_2 PF13180.1 EGC34184.1 - 0.00011 22.0 0.0 0.00046 20.0 0.0 2.0 1 1 0 1 1 1 1 PDZ domain DUF3610 PF12272.3 EGC34184.1 - 0.0083 15.7 0.5 0.017 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3610) FadA PF09403.5 EGC34184.1 - 0.052 13.5 2.3 0.078 12.9 0.1 2.0 2 0 0 2 2 2 0 Adhesion protein FadA DUF1048 PF06304.6 EGC34184.1 - 0.077 13.3 0.0 0.16 12.3 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1048) IncA PF04156.9 EGC34184.1 - 0.21 11.1 2.6 0.45 10.0 1.8 1.5 1 1 0 1 1 1 0 IncA protein Spectrin PF00435.16 EGC34184.1 - 0.51 10.6 4.8 2.7 8.3 2.7 2.1 1 1 0 1 1 1 0 Spectrin repeat DUF3573 PF12097.3 EGC34184.1 - 0.55 8.7 4.4 0.56 8.7 1.8 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3573) DUF4200 PF13863.1 EGC34184.1 - 1.4 8.8 9.3 2.4 8.1 1.7 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Sipho_Gp157 PF05565.6 EGC34184.1 - 1.7 8.1 6.2 7.6 6.0 4.3 1.9 1 1 0 1 1 1 0 Siphovirus Gp157 EAP30 PF04157.11 EGC34184.1 - 2.1 7.4 5.2 3.8 6.5 0.3 2.2 2 0 0 2 2 2 0 EAP30/Vps36 family TMF_DNA_bd PF12329.3 EGC34184.1 - 2.2 8.1 9.0 7.6 6.4 0.6 2.6 2 0 0 2 2 2 0 TATA element modulatory factor 1 DNA binding APG17 PF04108.7 EGC34184.1 - 4.6 5.9 9.2 22 3.6 6.4 1.9 1 1 0 1 1 1 0 Autophagy protein Apg17 Tropomyosin_1 PF12718.2 EGC34184.1 - 5.2 6.9 11.6 4.9 7.0 1.2 2.2 2 0 0 2 2 2 0 Tropomyosin like Acetyltransf_1 PF00583.19 EGC34185.1 - 4.1e-14 52.3 0.0 6.2e-14 51.8 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC34185.1 - 1.5e-05 25.1 0.0 2.2e-05 24.5 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC34185.1 - 1.9e-05 24.7 0.0 5.4e-05 23.2 0.0 1.7 1 1 1 2 2 2 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC34185.1 - 0.00042 20.0 0.0 0.00066 19.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGC34185.1 - 0.0083 16.2 0.1 0.02 15.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Vfa1 PF08432.5 EGC34185.1 - 0.092 12.7 15.0 0.14 12.1 10.4 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RP-C_C PF11800.3 EGC34185.1 - 0.2 11.3 3.1 0.27 10.8 2.2 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region Ctr PF04145.10 EGC34185.1 - 0.21 11.6 3.7 0.37 10.8 2.6 1.3 1 0 0 1 1 1 0 Ctr copper transporter family GCD14 PF08704.5 EGC34185.1 - 0.23 10.9 3.2 0.3 10.5 2.2 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Peptidase_S49_N PF08496.5 EGC34185.1 - 0.34 10.6 6.6 0.49 10.1 4.6 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1510 PF07423.6 EGC34185.1 - 1.4 8.2 15.7 1.8 7.8 10.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EGC34185.1 - 3.4 6.3 13.9 4.1 6.1 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) GTP_EFTU PF00009.22 EGC34186.1 - 6.8e-30 103.9 2.0 1.4e-29 102.8 0.4 2.3 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGC34186.1 - 8.5e-18 64.2 0.3 2.6e-17 62.6 0.2 1.9 1 0 0 1 1 1 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGC34186.1 - 5.7e-10 39.1 3.1 0.0001 22.3 0.2 3.4 2 1 1 3 3 3 2 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGC34186.1 - 0.00063 19.3 0.8 0.00063 19.3 0.6 2.3 2 0 0 2 2 2 1 Elongation factor Tu domain 4 ArgK PF03308.11 EGC34186.1 - 0.023 13.4 0.2 0.044 12.5 0.1 1.4 1 0 0 1 1 1 0 ArgK protein DUF2678 PF10856.3 EGC34187.1 - 1.9e-05 24.3 0.9 3.1e-05 23.6 0.6 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2678) P5-ATPase PF12409.3 EGC34187.1 - 0.044 13.6 0.1 0.1 12.4 0.1 1.6 1 0 0 1 1 1 0 P5-type ATPase cation transporter DUF4131 PF13567.1 EGC34187.1 - 0.07 12.5 0.9 0.15 11.4 0.6 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) DUF3366 PF11846.3 EGC34187.1 - 0.14 12.0 0.0 0.18 11.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3366) AMP-binding PF00501.23 EGC34188.1 - 1.8e-75 253.8 0.0 2.4e-75 253.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34188.1 - 5e-06 27.3 0.0 1e-05 26.3 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UDG PF03167.14 EGC34188.1 - 0.041 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Pox_A_type_inc PF04508.7 EGC34188.1 - 0.15 11.9 1.0 0.48 10.3 0.7 1.9 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AMP-binding PF00501.23 EGC34189.1 - 1.1e-76 257.9 0.0 1.4e-76 257.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34189.1 - 6.2e-06 27.0 0.0 1.3e-05 26.0 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain UDG PF03167.14 EGC34189.1 - 0.025 14.0 0.0 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Uracil DNA glycosylase superfamily Pox_A_type_inc PF04508.7 EGC34189.1 - 0.14 11.9 1.0 0.48 10.3 0.7 2.0 1 0 0 1 1 1 0 Viral A-type inclusion protein repeat AMP-binding PF00501.23 EGC34190.1 - 9.2e-75 251.5 0.0 1.2e-74 251.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34190.1 - 3.5e-07 31.0 0.0 7.1e-07 30.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGC34191.1 - 3.8e-76 256.1 0.0 4.9e-76 255.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34191.1 - 4.5e-07 30.7 0.0 8.9e-07 29.7 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Pox_A_type_inc PF04508.7 EGC34191.1 - 0.27 11.1 3.1 0.48 10.3 0.7 2.5 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat zf-CCHC PF00098.18 EGC34193.1 - 1.4e-06 27.8 1.4 2.4e-06 27.2 1.0 1.4 1 0 0 1 1 1 1 Zinc knuckle FNIP PF05725.7 EGC34194.1 - 4.9e-239 772.2 145.7 2.4e-16 59.3 0.9 20.2 12 3 6 22 22 22 21 FNIP Repeat Phage_min_tail PF05939.8 EGC34194.1 - 4.4e-12 45.9 0.1 25 4.8 0.0 12.1 8 6 6 14 14 14 5 Phage minor tail protein FNIP PF05725.7 EGC34195.1 - 3.2e-81 267.0 59.0 1.2e-16 60.3 1.0 7.6 5 1 0 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC34195.1 - 1.7e-06 27.8 17.9 2.1 8.3 0.3 8.5 4 2 5 9 9 9 3 Protein of unknown function (DUF1769) TnpW PF14202.1 EGC34195.1 - 0.061 12.9 0.0 43 3.8 0.0 3.4 3 0 0 3 3 3 0 Transposon-encoded protein TnpW DUF2845 PF11006.3 EGC34196.1 - 0.73 9.7 4.6 0.81 9.5 3.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2845) PROCN PF08083.6 EGC34196.1 - 1.3 7.4 11.0 1.4 7.2 7.6 1.0 1 0 0 1 1 1 0 PROCN (NUC071) domain FlaF PF07309.6 EGC34196.1 - 1.5 8.7 8.0 1.8 8.4 5.6 1.2 1 0 0 1 1 1 0 Flagellar protein FlaF K_trans PF02705.11 EGC34196.1 - 2.5 6.3 5.7 2.5 6.3 3.9 1.0 1 0 0 1 1 1 0 K+ potassium transporter DUF4206 PF13901.1 EGC34196.1 - 2.9 7.3 9.5 3.2 7.2 6.6 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) CIA30 PF08547.7 EGC34196.1 - 3.3 7.5 8.4 3.5 7.4 5.8 1.0 1 0 0 1 1 1 0 Complex I intermediate-associated protein 30 (CIA30) DASH_Spc19 PF08287.6 EGC34196.1 - 6.2 6.4 17.0 7.1 6.2 11.8 1.1 1 0 0 1 1 1 0 Spc19 P12 PF12669.2 EGC34197.1 - 0.16 12.1 6.6 0.27 11.4 4.6 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family YWFCY PF14293.1 EGC34197.1 - 0.41 10.5 3.4 0.71 9.7 2.3 1.4 1 0 0 1 1 1 0 YWFCY protein Claudin_3 PF06653.6 EGC34197.1 - 0.84 9.3 5.8 1.2 8.7 4.1 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF1201 PF06716.6 EGC34197.1 - 1.1 9.0 7.4 1.8 8.4 5.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1201) Chordopox_A13L PF05961.6 EGC34197.1 - 2.1 8.3 5.7 4 7.4 3.9 1.6 1 1 0 1 1 1 0 Chordopoxvirus A13L protein WD40 PF00400.27 EGC34198.1 - 7e-22 76.4 7.4 3.6e-06 26.6 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat RAB3GAP2_N PF14655.1 EGC34198.1 - 4.3e-05 22.7 0.1 4.3e-05 22.7 0.0 2.3 3 0 0 3 3 3 1 Rab3 GTPase-activating protein regulatory subunit N-terminus EGF_2 PF07974.8 EGC34198.1 - 0.48 10.6 10.0 1.3 9.2 7.0 1.7 1 0 0 1 1 1 0 EGF-like domain DUF788 PF05620.6 EGC34199.1 - 1.3e-46 158.5 0.7 1.5e-46 158.3 0.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF788) MFS_Mycoplasma PF07672.8 EGC34199.1 - 0.0014 17.8 0.4 0.048 12.8 0.1 2.1 1 1 1 2 2 2 2 Mycoplasma MFS transporter ABC2_membrane_6 PF06182.6 EGC34199.1 - 0.022 14.3 0.5 0.022 14.3 0.4 1.6 1 1 1 2 2 2 0 ABC-2 family transporter protein DUF4206 PF13901.1 EGC34200.1 - 1.6e-51 174.7 12.1 4.8e-51 173.1 8.4 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF4206) RUN PF02759.14 EGC34200.1 - 1.7e-18 66.6 6.3 1.1e-16 60.8 0.2 3.3 3 0 0 3 3 3 2 RUN domain zinc-ribbons_6 PF07191.7 EGC34200.1 - 3 7.6 9.2 0.17 11.7 1.1 2.6 2 0 0 2 2 2 0 zinc-ribbons Ufm1 PF03671.9 EGC34201.1 - 7e-41 137.8 0.4 7.9e-41 137.6 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin fold modifier 1 protein GFA PF04828.9 EGC34202.1 - 3e-08 33.4 0.0 3e-08 33.4 0.0 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cytochrome_C554 PF13435.1 EGC34202.1 - 0.00073 19.5 1.7 0.001 19.1 1.2 1.1 1 0 0 1 1 1 1 Cytochrome c554 and c-prime Cys_rich_CWC PF14375.1 EGC34202.1 - 0.032 14.1 0.7 0.032 14.1 0.5 1.7 2 0 0 2 2 2 0 Cysteine-rich CWC Cytochrome_C7 PF14522.1 EGC34202.1 - 0.097 12.3 1.9 1.1 8.9 1.3 2.1 1 1 0 1 1 1 0 Cytochrome c7 ketoacyl-synt PF00109.21 EGC34204.1 - 4.5e-64 216.3 0.0 6.7e-64 215.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34204.1 - 2.8e-49 168.1 0.0 4.5e-49 167.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC34204.1 - 1.1e-38 132.5 0.0 2e-38 131.7 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC34204.1 - 1.2e-30 105.8 0.0 2.2e-30 104.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC34204.1 - 2.8e-22 79.2 0.0 1.3e-19 70.5 0.0 3.3 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC34204.1 - 2.3e-16 60.1 0.0 3.2e-14 53.1 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EGC34204.1 - 6.4e-16 58.3 0.0 1e-15 57.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC34204.1 - 1.2e-11 45.6 0.0 3.3e-11 44.1 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGC34204.1 - 1.9e-09 37.8 0.2 1.3e-08 35.1 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EGC34204.1 - 2.2e-09 37.0 0.0 4.8e-09 35.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC34204.1 - 5.6e-08 32.6 0.0 5e-07 29.5 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34204.1 - 3.8e-05 23.3 0.4 0.00024 20.7 0.3 2.4 1 0 0 1 1 1 1 Methyltransferase domain Epimerase PF01370.16 EGC34204.1 - 0.00012 21.6 0.0 0.058 12.8 0.0 3.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family Thiolase_N PF00108.18 EGC34204.1 - 0.00047 19.2 0.0 0.00088 18.3 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 EGC34204.1 - 0.0007 20.0 0.0 0.0039 17.6 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain NAD_binding_10 PF13460.1 EGC34204.1 - 0.003 17.6 0.0 0.061 13.3 0.0 2.5 2 0 0 2 2 2 1 NADH(P)-binding Methyltransf_18 PF12847.2 EGC34204.1 - 0.0067 16.9 0.2 0.21 12.2 0.3 3.3 2 1 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC34204.1 - 0.0097 16.1 0.3 0.03 14.5 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Ras PF00071.17 EGC34205.1 - 2.4e-35 121.3 0.3 2.9e-35 121.0 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34205.1 - 8.8e-24 84.2 0.1 5.8e-23 81.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC34205.1 - 4.1e-08 32.6 0.1 5.1e-08 32.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC34205.1 - 2.4e-07 30.1 0.3 2.9e-07 29.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC34205.1 - 0.00014 21.3 0.1 0.001 18.5 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain G-alpha PF00503.15 EGC34205.1 - 0.003 16.3 1.4 0.026 13.2 0.6 2.3 1 1 1 2 2 2 1 G-protein alpha subunit MMR_HSR1 PF01926.18 EGC34205.1 - 0.0079 16.1 0.0 0.014 15.3 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC34205.1 - 0.032 13.7 0.4 0.074 12.5 0.2 1.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC34205.1 - 0.044 13.0 0.1 0.055 12.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Tyr_Deacylase PF02580.11 EGC34206.1 - 9.3e-46 155.4 0.1 1.1e-45 155.1 0.0 1.1 1 0 0 1 1 1 1 D-Tyr-tRNA(Tyr) deacylase PKD_channel PF08016.7 EGC34207.1 - 6.6e-11 41.2 7.6 1.1e-10 40.5 5.3 1.4 1 0 0 1 1 1 1 Polycystin cation channel Ion_trans PF00520.26 EGC34207.1 - 0.00051 19.3 21.6 0.00051 19.3 15.0 3.5 2 1 1 3 3 3 1 Ion transport protein Coa1 PF08695.5 EGC34207.1 - 0.063 12.7 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 Cytochrome oxidase complex assembly protein 1 LRR_8 PF13855.1 EGC34208.1 - 4.6e-22 77.5 33.1 9.4e-07 28.4 0.4 6.8 5 1 1 6 6 6 6 Leucine rich repeat LRR_4 PF12799.2 EGC34208.1 - 4.8e-16 57.9 49.9 0.00048 19.6 0.0 11.0 5 3 7 12 12 12 10 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC34208.1 - 2.2e-09 36.0 36.3 0.45 10.7 0.1 13.7 11 3 1 12 12 12 5 Leucine Rich Repeat Zip PF02535.17 EGC34208.1 - 0.0083 15.1 0.0 0.0083 15.1 0.0 2.2 3 0 0 3 3 3 1 ZIP Zinc transporter LRR_6 PF13516.1 EGC34208.1 - 1.8 8.8 35.6 0.18 11.9 0.1 10.6 10 3 2 12 12 12 0 Leucine Rich repeat MFS_1 PF07690.11 EGC34209.1 - 7.4e-30 103.8 46.9 2.9e-26 92.0 20.6 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC34209.1 - 3e-06 26.0 21.1 7.4e-06 24.7 3.7 3.2 2 1 1 3 3 3 3 Sugar (and other) transporter CytB6-F_Fe-S PF08802.5 EGC34209.1 - 5.3 7.1 6.2 24 5.0 0.4 3.6 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit Glutaredoxin PF00462.19 EGC34210.1 - 1.7e-05 24.6 0.0 6.3e-05 22.8 0.0 2.0 1 1 0 1 1 1 1 Glutaredoxin PUA PF01472.15 EGC34210.1 - 0.12 12.0 0.0 0.22 11.2 0.0 1.4 1 0 0 1 1 1 0 PUA domain Arfaptin PF06456.8 EGC34211.1 - 0.013 14.8 0.4 0.019 14.3 0.3 1.3 1 0 0 1 1 1 0 Arfaptin-like domain DUF2614 PF11023.3 EGC34211.1 - 0.024 14.4 3.3 0.035 13.8 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) gp32 PF08804.5 EGC34211.1 - 0.16 12.0 1.0 0.27 11.3 0.7 1.3 1 0 0 1 1 1 0 gp32 DNA binding protein like UQ_con PF00179.21 EGC34212.1 - 3.3e-47 159.4 0.3 3.7e-47 159.2 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC34212.1 - 0.00036 20.3 0.0 0.00045 19.9 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC34212.1 - 0.0018 18.1 0.4 0.0026 17.6 0.3 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EGC34212.1 - 0.0033 17.0 0.5 0.0067 16.0 0.2 1.5 1 1 0 1 1 1 1 UEV domain Erf4 PF10256.4 EGC34213.1 - 0.00024 20.9 3.6 0.0035 17.1 2.5 2.3 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF2207 PF09972.4 EGC34213.1 - 0.0085 14.7 2.7 0.012 14.2 1.9 1.3 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) IncA PF04156.9 EGC34213.1 - 0.096 12.2 10.3 0.3 10.6 7.1 1.7 1 1 0 1 1 1 0 IncA protein PAT1 PF09770.4 EGC34213.1 - 6.8 4.7 22.3 8.1 4.5 15.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 zf-UBR PF02207.15 EGC34214.1 - 2.7e-11 43.0 12.8 2.7e-11 43.0 8.9 3.7 3 1 0 3 3 3 1 Putative zinc finger in N-recognin (UBR box) PHD PF00628.24 EGC34214.1 - 2.4e-07 30.3 7.7 2.4e-07 30.3 5.4 4.7 3 1 1 4 4 4 1 PHD-finger SSP160 PF06933.6 EGC34214.1 - 0.67 7.8 16.5 0.94 7.3 11.5 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC34214.1 - 5.8 6.6 27.6 10 5.8 19.2 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein LIM PF00412.17 EGC34216.1 - 4.1e-29 100.4 38.7 2e-12 46.9 3.7 3.2 3 0 0 3 3 3 3 LIM domain WH2 PF02205.15 EGC34216.1 - 6.4e-08 31.9 0.2 3.5e-07 29.6 0.1 2.3 2 0 0 2 2 2 1 WH2 motif Thymosin PF01290.15 EGC34216.1 - 7.1e-05 22.3 0.0 0.00014 21.3 0.0 1.5 1 0 0 1 1 1 1 Thymosin beta-4 family Pkinase PF00069.20 EGC34217.1 - 6.5e-65 218.8 0.0 1.1e-64 218.1 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34217.1 - 5.6e-50 169.8 0.0 8.3e-50 169.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC34217.1 - 2.4e-05 23.4 0.0 4.1e-05 22.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like DUF927 PF06048.6 EGC34217.1 - 0.092 11.9 0.1 5.7 6.1 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF927) MSP1_C PF07462.6 EGC34217.1 - 0.17 10.2 7.4 0.023 13.1 1.7 1.9 2 0 0 2 2 2 0 Merozoite surface protein 1 (MSP1) C-terminus IF-2B PF01008.12 EGC34218.1 - 1.9e-78 263.3 0.4 2.6e-78 262.8 0.3 1.2 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF515 PF04415.7 EGC34218.1 - 0.0017 16.7 3.8 0.0022 16.2 2.6 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF515) Death PF00531.17 EGC34218.1 - 0.063 13.0 0.1 1.5 8.6 0.0 2.3 2 0 0 2 2 2 0 Death domain Med3 PF11593.3 EGC34218.1 - 0.37 9.9 6.8 0.13 11.4 2.8 1.6 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal Period_C PF12114.3 EGC34218.1 - 0.61 9.6 8.3 1.2 8.7 5.8 1.4 1 0 0 1 1 1 0 Period protein 2/3C-terminal region MAP65_ASE1 PF03999.7 EGC34218.1 - 6 5.3 12.4 2.8 6.4 0.0 2.4 1 1 1 2 2 2 0 Microtubule associated protein (MAP65/ASE1 family) 7tm_2 PF00002.19 EGC34219.1 - 2.6e-05 23.4 13.5 2.6e-05 23.4 9.4 1.9 1 1 1 2 2 2 1 7 transmembrane receptor (Secretin family) Frizzled PF01534.12 EGC34219.1 - 0.00029 19.7 13.1 0.00041 19.2 9.1 1.2 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF4281 PF14108.1 EGC34219.1 - 0.0046 17.0 1.9 0.18 11.8 0.2 2.6 2 1 0 2 2 2 1 Domain of unknown function (DUF4281) MarC PF01914.12 EGC34219.1 - 0.1 11.7 7.2 2.8 7.0 2.4 2.3 2 0 0 2 2 2 0 MarC family integral membrane protein Amastin PF07344.6 EGC34219.1 - 1.2 8.6 9.4 1.2e+02 2.2 6.5 2.3 1 1 0 1 1 1 0 Amastin surface glycoprotein ORC4_C PF14629.1 EGC34220.1 - 0.02 14.2 0.0 0.03 13.7 0.0 1.1 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 4 C-terminus DUF1741 PF08427.5 EGC34221.1 - 2e-80 269.6 0.9 6.9e-80 267.9 0.4 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1741) Adaptin_N PF01602.15 EGC34223.1 - 3.3e-140 467.9 14.2 4.1e-140 467.5 9.8 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Alpha_adaptinC2 PF02883.15 EGC34223.1 - 1.4e-25 89.8 1.8 1.4e-25 89.8 1.3 2.6 3 0 0 3 3 3 1 Adaptin C-terminal domain Cnd1 PF12717.2 EGC34223.1 - 6.1e-06 26.1 3.4 0.00036 20.4 0.4 3.0 2 0 0 2 2 2 1 non-SMC mitotic condensation complex subunit 1 HEAT_2 PF13646.1 EGC34223.1 - 0.00015 21.9 0.1 0.21 11.9 0.0 4.0 4 2 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EGC34223.1 - 0.0028 17.5 1.4 0.94 9.7 0.0 4.6 5 0 0 5 5 5 1 HEAT repeat TIP120 PF08623.5 EGC34223.1 - 0.0092 15.5 2.8 0.018 14.6 0.1 2.7 2 1 1 3 3 3 1 TATA-binding protein interacting (TIP20) DUF2435 PF10363.4 EGC34223.1 - 0.017 14.9 0.3 0.18 11.7 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2435) HEAT_EZ PF13513.1 EGC34223.1 - 0.075 13.5 0.1 20 5.8 0.0 3.6 3 0 0 3 3 3 0 HEAT-like repeat Arm PF00514.18 EGC34223.1 - 0.13 12.1 3.4 60 3.6 0.0 4.9 5 0 0 5 5 5 0 Armadillo/beta-catenin-like repeat FNIP PF05725.7 EGC34224.1 - 1.3e-37 127.4 16.8 3.5e-11 42.8 0.1 4.5 4 0 0 4 4 4 4 FNIP Repeat DUF1769 PF08588.5 EGC34224.1 - 0.052 13.5 5.1 4 7.4 0.1 4.7 3 1 3 6 6 6 0 Protein of unknown function (DUF1769) RhoGEF PF00621.15 EGC34225.1 - 1.1e-53 181.7 6.1 1.1e-53 181.7 4.2 3.0 3 0 0 3 3 3 1 RhoGEF domain Terpene_synth_C PF03936.11 EGC34225.1 - 6.1e-09 35.4 1.0 1.3e-08 34.4 0.7 1.5 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PI3_PI4_kinase PF00454.22 EGC34226.1 - 2.6e-43 148.1 0.0 9.8e-43 146.2 0.0 2.1 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGC34226.1 - 3.7e-42 143.6 6.2 3.7e-42 143.6 4.3 2.6 2 0 0 2 2 2 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3K_C2 PF00792.19 EGC34226.1 - 3.4e-11 43.0 0.5 3.4e-11 43.0 0.3 2.3 2 0 0 2 2 2 1 Phosphoinositide 3-kinase C2 DKCLD PF08068.7 EGC34227.1 - 1.2e-32 111.6 2.2 9.8e-32 108.6 0.3 3.1 3 0 0 3 3 3 1 DKCLD (NUC011) domain PUA PF01472.15 EGC34227.1 - 2.9e-21 74.9 1.0 6.1e-21 73.9 0.7 1.6 1 0 0 1 1 1 1 PUA domain TruB_N PF01509.13 EGC34227.1 - 2.7e-19 69.7 10.6 4.9e-19 68.9 0.2 4.0 2 1 0 2 2 2 1 TruB family pseudouridylate synthase (N terminal domain) SET PF00856.23 EGC34227.1 - 1.8 8.8 9.2 0.075 13.3 2.0 2.0 2 0 0 2 2 2 0 SET domain CDC27 PF09507.5 EGC34227.1 - 6 5.9 62.8 0.024 13.9 33.6 2.1 2 0 0 2 2 2 0 DNA polymerase subunit Cdc27 LRR_4 PF12799.2 EGC34228.1 - 7.8e-06 25.3 13.9 0.0046 16.5 4.9 2.7 2 2 0 2 2 2 2 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC34228.1 - 4.7e-05 22.8 11.7 0.0067 16.3 0.8 4.6 4 1 1 5 5 5 2 Leucine Rich Repeat LRR_8 PF13855.1 EGC34228.1 - 0.00082 19.0 8.3 0.053 13.2 3.7 2.4 1 1 1 2 2 2 2 Leucine rich repeat FNIP PF05725.7 EGC34228.1 - 0.0014 18.5 1.0 0.067 13.1 0.0 2.7 1 1 1 2 2 2 2 FNIP Repeat LRR_7 PF13504.1 EGC34228.1 - 0.002 18.0 3.0 2.6 8.6 0.0 3.6 3 0 0 3 3 3 1 Leucine rich repeat LRR_6 PF13516.1 EGC34228.1 - 0.0029 17.5 8.2 0.33 11.1 1.1 3.4 2 1 1 3 3 3 2 Leucine Rich repeat Alpha-amylase PF00128.19 EGC34229.1 - 2.5e-77 260.3 0.0 5.1e-77 259.3 0.0 1.4 1 0 0 1 1 1 1 Alpha amylase, catalytic domain Glyco_hydro_70 PF02324.11 EGC34229.1 - 0.00017 19.5 0.3 0.035 11.9 0.0 2.2 2 0 0 2 2 2 2 Glycosyl hydrolase family 70 RTC PF01137.16 EGC34230.1 - 5e-71 238.1 0.0 5.7e-71 237.9 0.0 1.0 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGC34230.1 - 1.8e-33 114.6 0.0 2.9e-33 113.9 0.0 1.3 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain SPT16 PF08644.6 EGC34231.1 - 2e-48 164.0 0.1 2e-48 164.0 0.1 3.7 4 0 0 4 4 4 1 FACT complex subunit (SPT16/CDC68) FACT-Spt16_Nlob PF14826.1 EGC34231.1 - 2.7e-41 140.8 1.7 2.7e-41 140.8 1.2 2.8 2 0 0 2 2 2 1 FACT complex subunit SPT16 N-terminal lobe domain Peptidase_M24 PF00557.19 EGC34231.1 - 2e-31 109.2 0.0 3e-31 108.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 Rtt106 PF08512.7 EGC34231.1 - 6e-20 71.0 0.3 2.3e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 Histone chaperone Rttp106-like DNA_pol_A PF00476.15 EGC34232.1 - 6.1e-59 199.5 1.8 4e-51 173.8 0.2 3.1 2 1 0 2 2 2 2 DNA polymerase family A RasGEF PF00617.14 EGC34233.1 - 3.9e-48 163.6 3.9 1.1e-47 162.1 2.7 1.8 1 0 0 1 1 1 1 RasGEF domain cNMP_binding PF00027.24 EGC34233.1 - 4.5e-17 61.6 2.4 4.4e-08 32.8 0.0 3.4 2 1 0 2 2 2 2 Cyclic nucleotide-binding domain RasGEF_N PF00618.15 EGC34233.1 - 8.1e-16 58.0 1.2 8.1e-16 58.0 0.8 3.7 5 0 0 5 5 5 1 RasGEF N-terminal motif GRAM PF02893.15 EGC34233.1 - 2e-08 33.6 2.4 4e-08 32.6 0.2 2.5 2 0 0 2 2 2 1 GRAM domain DSPc PF00782.15 EGC34235.1 - 4.5e-29 100.7 0.4 1.2e-28 99.3 0.0 1.8 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC34235.1 - 0.00013 21.4 1.0 0.00022 20.6 0.0 1.8 2 0 0 2 2 2 1 Protein-tyrosine phosphatase RNA_pol_N PF01194.12 EGC34235.1 - 0.0032 17.4 0.5 0.082 12.9 0.1 3.1 2 0 0 2 2 2 1 RNA polymerases N / 8 kDa subunit PTPlike_phytase PF14566.1 EGC34235.1 - 0.004 17.1 3.5 0.034 14.1 0.0 2.3 2 0 0 2 2 2 1 Inositol hexakisphosphate Lin-8 PF03353.10 EGC34235.1 - 0.064 12.5 14.5 0.094 11.9 10.1 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Daxx PF03344.10 EGC34235.1 - 0.084 11.3 23.6 0.12 10.7 16.4 1.2 1 0 0 1 1 1 0 Daxx Family Y_phosphatase3 PF13350.1 EGC34235.1 - 0.084 13.1 2.8 0.15 12.3 0.0 2.3 2 1 0 2 2 2 0 Tyrosine phosphatase family DUF1500 PF07389.7 EGC34235.1 - 0.12 12.4 0.2 1.3 9.1 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1500) Yippee-Mis18 PF03226.9 EGC34235.1 - 0.2 11.7 5.9 0.24 11.4 1.9 2.5 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly YL1 PF05764.8 EGC34235.1 - 0.21 11.1 20.0 0.35 10.4 13.8 1.3 1 0 0 1 1 1 0 YL1 nuclear protein Ycf1 PF05758.7 EGC34235.1 - 0.27 8.8 8.9 0.35 8.5 6.2 1.1 1 0 0 1 1 1 0 Ycf1 BUD22 PF09073.5 EGC34235.1 - 0.34 9.9 23.4 0.47 9.4 16.2 1.1 1 0 0 1 1 1 0 BUD22 C1_4 PF07975.7 EGC34235.1 - 0.53 10.3 4.1 0.31 11.0 0.2 2.3 2 0 0 2 2 2 0 TFIIH C1-like domain TFIIF_alpha PF05793.7 EGC34235.1 - 6.1 5.1 33.3 8.8 4.5 23.1 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Erf4 PF10256.4 EGC34236.1 - 0.0034 17.2 1.0 0.0034 17.2 0.7 1.9 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF4191 PF13829.1 EGC34236.1 - 0.012 14.7 0.9 0.015 14.3 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4179 PF13786.1 EGC34236.1 - 0.03 14.5 1.5 0.049 13.8 0.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4179) PhrC_PhrF PF11131.3 EGC34236.1 - 0.03 13.9 0.5 0.054 13.0 0.4 1.3 1 0 0 1 1 1 0 Rap-phr extracellular signalling DUF4131 PF13567.1 EGC34236.1 - 0.074 12.4 0.7 0.11 11.9 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Pex24p PF06398.6 EGC34236.1 - 0.29 9.8 7.1 0.4 9.4 4.2 1.4 1 1 1 2 2 2 0 Integral peroxisomal membrane peroxin Chordopox_G3 PF06129.7 EGC34236.1 - 0.84 9.8 3.5 17 5.6 0.0 2.7 3 0 0 3 3 3 0 Chordopoxvirus G3 protein Pkinase PF00069.20 EGC34237.1 - 1e-24 87.1 0.0 1e-24 87.1 0.0 3.2 4 0 0 4 4 4 1 Protein kinase domain WD40 PF00400.27 EGC34237.1 - 1.5e-20 72.2 1.4 3.5e-06 26.6 0.0 5.2 5 0 0 5 5 5 4 WD domain, G-beta repeat HEAT_2 PF13646.1 EGC34237.1 - 0.00011 22.4 0.0 0.7 10.2 0.0 3.5 2 1 1 3 3 3 3 HEAT repeats HEAT PF02985.17 EGC34237.1 - 0.00011 21.9 7.7 0.052 13.6 0.1 5.2 5 0 0 5 5 5 2 HEAT repeat APH PF01636.18 EGC34237.1 - 0.043 13.5 0.9 0.071 12.8 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family RhoGEF PF00621.15 EGC34238.1 - 1.4e-49 168.3 4.5 1.4e-49 168.3 3.1 2.4 2 0 0 2 2 2 1 RhoGEF domain PX PF00787.19 EGC34238.1 - 2.2e-18 66.0 3.5 3.2e-18 65.5 1.1 2.3 3 0 0 3 3 3 1 PX domain Cyt-b5 PF00173.23 EGC34240.1 - 1.5e-13 50.2 0.0 2.5e-13 49.6 0.0 1.3 1 1 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain DUF4318 PF14201.1 EGC34240.1 - 0.027 14.2 0.1 0.05 13.4 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4318) GIIM PF08388.6 EGC34240.1 - 0.078 12.7 0.0 0.16 11.7 0.0 1.5 1 0 0 1 1 1 0 Group II intron, maturase-specific domain Kelch_1 PF01344.20 EGC34241.1 - 2.3e-40 135.9 22.8 8.1e-12 44.4 0.3 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGC34241.1 - 2.8e-36 122.8 9.4 1.4e-11 44.2 0.1 7.3 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC34241.1 - 5.6e-34 114.9 23.0 4.3e-07 29.8 0.3 6.4 5 1 1 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC34241.1 - 5.5e-32 109.2 27.0 6.3e-08 32.3 0.2 6.3 6 0 0 6 6 6 6 Kelch motif Kelch_4 PF13418.1 EGC34241.1 - 1.3e-28 98.4 18.2 7.3e-06 25.6 0.9 6.6 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_2 PF07646.10 EGC34241.1 - 3.2e-25 86.8 16.4 1.2e-05 24.9 0.1 6.5 6 0 0 6 6 6 6 Kelch motif F-box-like PF12937.2 EGC34241.1 - 3.6e-10 39.3 0.5 8.6e-10 38.1 0.0 1.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC34241.1 - 5.2e-05 22.7 0.8 5.2e-05 22.7 0.5 2.1 2 0 0 2 2 2 1 F-box domain RNA_pol_Rpc34 PF05158.7 EGC34242.1 - 1.3e-79 267.7 3.8 4.1e-55 187.2 1.6 2.0 1 1 1 2 2 2 2 RNA polymerase Rpc34 subunit B-block_TFIIIC PF04182.7 EGC34242.1 - 7.9e-06 25.6 0.2 1.7e-05 24.5 0.1 1.6 2 0 0 2 2 2 1 B-block binding subunit of TFIIIC TrmB PF01978.14 EGC34242.1 - 0.0018 17.9 0.1 0.09 12.4 0.1 2.4 2 0 0 2 2 2 1 Sugar-specific transcriptional regulator TrmB EF-hand_9 PF14658.1 EGC34242.1 - 0.0029 17.4 0.1 0.013 15.4 0.0 2.0 2 0 0 2 2 2 1 EF-hand domain RPA_C PF08784.6 EGC34242.1 - 0.0085 16.4 0.3 1.6 9.2 0.0 2.5 1 1 1 2 2 2 1 Replication protein A C terminal Cyclin_C PF02984.14 EGC34242.1 - 0.042 13.7 0.2 0.1 12.5 0.0 1.7 2 0 0 2 2 2 0 Cyclin, C-terminal domain TFIIE_alpha PF02002.12 EGC34242.1 - 0.047 13.1 0.2 2.2 7.8 0.0 2.4 2 0 0 2 2 2 0 TFIIE alpha subunit GHMP_kinases_N PF00288.21 EGC34243.1 - 1.4e-17 63.5 0.3 3.5e-17 62.2 0.2 1.7 1 0 0 1 1 1 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGC34243.1 - 4.5e-07 29.9 0.0 1.2e-06 28.5 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal Actin PF00022.14 EGC34244.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC34244.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) AAA PF00004.24 EGC34245.1 - 1.8e-50 170.5 0.1 3.8e-39 133.9 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGC34245.1 - 3.2e-06 26.1 0.0 0.00022 20.1 0.0 2.4 2 0 0 2 2 2 1 TIP49 C-terminus DUF815 PF05673.8 EGC34245.1 - 1.2e-05 24.4 0.0 0.00086 18.3 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_14 PF13173.1 EGC34245.1 - 5.2e-05 23.1 1.7 0.0021 17.9 0.0 3.4 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGC34245.1 - 0.00021 21.3 0.2 0.00087 19.3 0.0 2.1 2 1 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGC34245.1 - 0.00045 21.0 0.0 1.9 9.3 0.0 3.8 3 1 0 3 3 3 1 AAA domain AAA_5 PF07728.9 EGC34245.1 - 0.00089 18.9 0.0 0.047 13.4 0.0 3.5 3 1 0 3 3 3 1 AAA domain (dynein-related subfamily) RNA_helicase PF00910.17 EGC34245.1 - 0.001 19.2 0.1 0.0057 16.8 0.0 2.3 2 0 0 2 2 2 1 RNA helicase ABC_tran PF00005.22 EGC34245.1 - 0.0031 17.7 0.1 0.0031 17.7 0.0 2.6 2 1 1 3 3 2 1 ABC transporter AAA_22 PF13401.1 EGC34245.1 - 0.0032 17.6 0.2 0.8 9.8 0.0 2.9 1 1 1 2 2 2 1 AAA domain AAA_29 PF13555.1 EGC34245.1 - 0.017 14.6 0.0 0.045 13.2 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF258 PF03193.11 EGC34245.1 - 0.028 13.6 0.1 0.67 9.1 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Viral_helicase1 PF01443.13 EGC34245.1 - 0.11 12.0 0.0 0.57 9.6 0.0 2.2 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EGC34245.1 - 0.13 11.6 0.0 0.3 10.4 0.0 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGC34245.1 - 0.89 8.9 2.6 1.7 7.9 0.1 2.6 2 1 1 3 3 3 0 AAA domain DUF4064 PF13273.1 EGC34246.1 - 0.02 15.0 0.6 0.02 15.0 0.4 3.8 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DcpS_C PF11969.3 EGC34247.1 - 6e-27 94.1 0.9 1.3e-26 93.1 0.7 1.6 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding HIT PF01230.18 EGC34247.1 - 1.1e-14 54.7 1.1 2.6e-14 53.5 0.0 2.1 2 0 0 2 2 2 1 HIT domain LMBR1 PF04791.11 EGC34247.1 - 0.1 11.1 3.6 0.11 11.1 2.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein Folate_carrier PF01770.13 EGC34247.1 - 0.64 8.4 2.4 0.95 7.9 1.7 1.2 1 0 0 1 1 1 0 Reduced folate carrier NAD_kinase PF01513.16 EGC34248.1 - 4.9e-52 176.4 0.0 6.6e-52 176.0 0.0 1.1 1 0 0 1 1 1 1 ATP-NAD kinase DAGK_cat PF00781.19 EGC34248.1 - 0.14 11.6 0.0 0.25 10.7 0.0 1.5 1 0 0 1 1 1 0 Diacylglycerol kinase catalytic domain FNIP PF05725.7 EGC34249.1 - 2.2e-32 110.7 66.1 9.8e-08 31.8 0.2 11.0 8 1 2 10 10 10 8 FNIP Repeat RF-1 PF00472.15 EGC34250.1 - 1.7e-16 60.0 2.3 2.1e-16 59.7 1.6 1.1 1 0 0 1 1 1 1 RF-1 domain AhpC-TSA PF00578.16 EGC34251.1 - 1.6e-29 102.0 0.2 2.1e-29 101.7 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC34251.1 - 1e-16 60.8 0.0 1.2e-16 60.6 0.0 1.1 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGC34251.1 - 0.00032 20.5 0.0 0.00045 20.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme Thioredoxin_8 PF13905.1 EGC34251.1 - 0.0045 17.0 0.1 0.0065 16.5 0.1 1.2 1 0 0 1 1 1 1 Thioredoxin-like RasGEF PF00617.14 EGC34252.1 - 3.3e-54 183.4 2.5 3.3e-54 183.4 1.7 2.9 3 0 0 3 3 3 1 RasGEF domain RasGEF_N PF00618.15 EGC34252.1 - 2e-16 59.9 3.5 1.3e-15 57.3 0.7 5.4 4 1 0 5 5 5 2 RasGEF N-terminal motif F-box-like PF12937.2 EGC34252.1 - 2.6e-13 49.4 9.1 1.4e-07 31.0 0.7 3.6 3 0 0 3 3 3 2 F-box-like F-box PF00646.28 EGC34252.1 - 3e-08 33.1 3.5 1.2e-05 24.8 0.9 3.5 3 0 0 3 3 3 2 F-box domain Ank_2 PF12796.2 EGC34253.1 - 2.4e-40 136.7 7.5 1.7e-11 44.3 0.0 5.1 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC34253.1 - 1.7e-35 120.7 3.8 6.5e-08 32.8 0.0 6.2 3 1 2 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EGC34253.1 - 1.8e-33 112.6 3.9 1.9e-05 24.2 0.0 7.5 7 0 0 7 7 7 6 Ankyrin repeat Ank_3 PF13606.1 EGC34253.1 - 3e-26 88.8 7.3 0.0019 18.2 0.0 8.6 7 1 0 7 7 7 5 Ankyrin repeat Ank_5 PF13857.1 EGC34253.1 - 9.7e-26 89.2 0.5 9.7e-07 28.8 0.0 6.4 4 2 1 5 5 5 5 Ankyrin repeats (many copies) F-box-like PF12937.2 EGC34253.1 - 3.9e-09 36.1 4.2 8.5e-09 35.0 2.9 1.6 1 0 0 1 1 1 1 F-box-like SH2 PF00017.19 EGC34253.1 - 2.1e-07 30.6 0.0 1.3e-06 28.0 0.0 2.5 2 0 0 2 2 2 1 SH2 domain F-box PF00646.28 EGC34253.1 - 1.9e-06 27.3 2.8 1.9e-06 27.3 1.9 2.2 2 0 0 2 2 2 1 F-box domain Lipase_GDSL PF00657.17 EGC34254.1 - 1.1e-12 48.3 0.5 2.2e-12 47.2 0.1 1.8 2 0 0 2 2 2 1 GDSL-like Lipase/Acylhydrolase SapB_2 PF03489.12 EGC34254.1 - 1.6e-06 27.9 1.0 4.4e-06 26.6 0.1 2.3 2 0 0 2 2 2 1 Saposin-like type B, region 2 Cu-binding_MopE PF11617.3 EGC34254.1 - 0.0038 16.9 1.2 0.0098 15.6 0.8 1.7 1 0 0 1 1 1 1 Protein metal binding site PALP PF00291.20 EGC34255.1 - 1.1e-62 212.0 0.0 1.3e-62 211.8 0.0 1.0 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme WD40 PF00400.27 EGC34256.1 - 2e-27 94.0 21.6 0.00012 21.7 0.0 11.0 11 0 0 11 11 11 8 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGC34256.1 - 0.00076 18.3 0.5 1.6 7.4 0.0 4.0 4 0 0 4 4 4 2 Coatomer WD associated region FNIP PF05725.7 EGC34257.1 - 1.2e-67 223.5 75.1 1e-10 41.4 0.0 14.5 10 3 5 15 15 15 13 FNIP Repeat LRR_8 PF13855.1 EGC34257.1 - 0.34 10.7 12.2 0.27 11.0 0.2 4.5 2 2 1 4 4 4 0 Leucine rich repeat PTR2 PF00854.16 EGC34258.1 - 2.4e-70 237.1 11.9 6.5e-68 229.2 5.8 2.3 1 1 1 2 2 2 2 POT family CbiM PF01891.11 EGC34258.1 - 0.032 13.8 0.1 0.032 13.8 0.1 3.2 4 0 0 4 4 4 0 Cobalt uptake substrate-specific transmembrane region PTR2 PF00854.16 EGC34259.1 - 1.1e-66 225.2 14.7 7.1e-66 222.4 5.2 2.4 1 1 1 2 2 2 2 POT family ATP-synt_8 PF00895.15 EGC34259.1 - 0.36 11.0 3.0 1.8 8.8 0.0 3.8 3 0 0 3 3 3 0 ATP synthase protein 8 CBFD_NFYB_HMF PF00808.18 EGC34260.1 - 9.7e-12 44.7 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FLO_LFY PF01698.11 EGC34260.1 - 0.0086 14.9 7.7 0.0081 15.0 5.3 1.1 1 0 0 1 1 1 1 Floricaula / Leafy protein GAGA_bind PF06217.7 EGC34260.1 - 0.017 15.0 6.8 0.018 15.0 4.7 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family HTH_25 PF13413.1 EGC34260.1 - 0.025 14.1 0.1 0.066 12.8 0.0 1.7 2 0 0 2 2 1 0 Helix-turn-helix domain Pox_Ag35 PF03286.9 EGC34260.1 - 0.054 13.0 15.6 0.068 12.6 10.8 1.2 1 0 0 1 1 1 0 Pox virus Ag35 surface protein Bromo_TP PF07524.8 EGC34260.1 - 0.059 13.1 0.0 0.091 12.5 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated DUF1510 PF07423.6 EGC34260.1 - 0.14 11.5 19.6 0.15 11.4 13.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2413 PF10310.4 EGC34260.1 - 0.16 10.7 13.4 0.16 10.7 9.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2413) RAP1 PF07218.6 EGC34260.1 - 0.17 9.9 11.3 0.19 9.7 7.9 1.0 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) DDHD PF02862.12 EGC34260.1 - 0.2 11.4 4.9 0.22 11.2 3.4 1.1 1 0 0 1 1 1 0 DDHD domain Peptidase_S49_N PF08496.5 EGC34260.1 - 0.23 11.2 6.9 0.27 10.9 4.8 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal DUF1764 PF08576.5 EGC34260.1 - 0.27 12.0 17.1 0.44 11.3 11.9 1.3 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF1764) Sporozoite_P67 PF05642.6 EGC34260.1 - 0.28 8.9 7.7 0.34 8.7 5.3 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen BTV_NS2 PF04514.7 EGC34260.1 - 0.45 9.3 12.0 0.52 9.1 8.3 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Ycf1 PF05758.7 EGC34260.1 - 0.5 8.0 8.1 0.44 8.1 5.6 1.1 1 0 0 1 1 1 0 Ycf1 RR_TM4-6 PF06459.7 EGC34260.1 - 0.74 9.6 12.0 0.78 9.5 8.3 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FAM178 PF14816.1 EGC34260.1 - 0.77 8.4 6.6 0.77 8.3 4.6 1.2 1 0 0 1 1 1 0 Family of unknown function, FAM178 CT47 PF15623.1 EGC34260.1 - 0.81 9.3 12.6 0.98 9.1 8.7 1.1 1 0 0 1 1 1 0 Cancer/testis gene family 47 Rtf2 PF04641.7 EGC34260.1 - 2.3 7.3 16.0 2.8 7.0 11.1 1.1 1 0 0 1 1 1 0 Rtf2 RING-finger Astro_capsid PF03115.9 EGC34260.1 - 2.4 6.2 5.9 2.8 6.0 4.1 1.0 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Tim54 PF11711.3 EGC34260.1 - 2.5 6.6 11.0 3.6 6.0 7.6 1.3 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 CobT PF06213.7 EGC34260.1 - 3.4 6.7 19.3 4.1 6.4 13.4 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT GCD14 PF08704.5 EGC34260.1 - 3.5 7.0 7.8 4.8 6.5 5.4 1.1 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit Vfa1 PF08432.5 EGC34260.1 - 7.1 6.6 23.8 9.3 6.2 16.5 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phospholip_B PF04916.8 EGC34261.1 - 1.9e-114 382.8 5.6 2.5e-114 382.4 3.9 1.0 1 0 0 1 1 1 1 Phospholipase B Baculo_19 PF04798.7 EGC34262.1 - 0.29 10.4 1.5 2 7.7 0.2 2.0 2 0 0 2 2 2 0 Baculovirus 19 kDa protein conserved region Ribosomal_L37 PF08561.5 EGC34263.1 - 1.3e-07 31.1 0.0 1.7e-07 30.7 0.0 1.3 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L37 Asn_synthase PF00733.16 EGC34264.1 - 1.5e-21 77.0 0.0 1.4e-14 54.2 0.0 2.3 1 1 1 2 2 2 2 Asparagine synthase GATase_7 PF13537.1 EGC34264.1 - 2.6e-06 27.1 0.0 7.4e-06 25.7 0.0 1.8 1 1 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC34264.1 - 0.0013 18.6 0.0 0.0032 17.4 0.0 1.7 1 1 0 1 1 1 1 Glutamine amidotransferase domain ATP_bind_3 PF01171.15 EGC34264.1 - 0.052 13.0 0.0 0.13 11.7 0.0 1.7 1 0 0 1 1 1 0 PP-loop family QueC PF06508.8 EGC34264.1 - 0.075 12.3 0.5 0.23 10.6 0.0 2.0 2 0 0 2 2 2 0 Queuosine biosynthesis protein QueC DUF763 PF05559.6 EGC34265.1 - 0.035 13.0 1.4 0.044 12.7 1.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF763) LOH1CR12 PF10158.4 EGC34265.1 - 0.056 13.2 0.7 0.085 12.6 0.5 1.3 1 0 0 1 1 1 0 Tumour suppressor protein LRR_6 PF13516.1 EGC34266.1 - 8.1e-15 53.1 22.9 0.0022 17.8 0.1 9.6 9 0 0 9 9 9 4 Leucine Rich repeat LRR_4 PF12799.2 EGC34266.1 - 1.1e-06 28.1 26.4 0.27 10.8 4.4 7.3 4 3 1 5 5 5 4 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC34266.1 - 4.2e-05 23.0 23.4 1.3 9.3 0.5 9.2 10 1 0 10 10 10 3 Leucine Rich Repeat LRR_8 PF13855.1 EGC34266.1 - 0.00034 20.2 21.3 1.5 8.6 1.2 6.3 3 2 3 6 6 6 5 Leucine rich repeat LRR_7 PF13504.1 EGC34266.1 - 0.0016 18.2 22.8 3.9 8.0 0.0 9.6 10 1 1 11 11 11 2 Leucine rich repeat WD40 PF00400.27 EGC34267.1 - 8.2e-13 47.7 3.8 0.0015 18.3 0.0 5.6 6 0 0 6 6 6 4 WD domain, G-beta repeat PITH PF06201.8 EGC34268.1 - 5.7e-41 139.8 0.0 6.9e-41 139.5 0.0 1.1 1 0 0 1 1 1 1 PITH domain PLDc PF00614.17 EGC34269.1 - 1.4e-20 72.3 1.7 2e-10 40.0 0.1 2.8 2 0 0 2 2 2 2 Phospholipase D Active site motif PLDc_2 PF13091.1 EGC34269.1 - 2.5e-15 56.3 1.3 1.2e-08 34.7 0.2 3.0 2 0 0 2 2 2 2 PLD-like domain DUF4407 PF14362.1 EGC34269.1 - 3.1 6.6 9.2 4.8 6.0 6.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) Arm PF00514.18 EGC34270.1 - 1.5e-22 78.5 2.5 9.6e-07 28.4 0.0 7.7 8 1 0 8 8 8 5 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EGC34270.1 - 0.00068 19.5 0.1 3.7 7.5 0.0 3.6 4 0 0 4 4 4 2 Rapamycin-insensitive companion of mTOR, domain 5 HEAT_2 PF13646.1 EGC34270.1 - 0.0033 17.6 0.0 0.087 13.1 0.0 3.0 2 2 2 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EGC34270.1 - 0.061 13.8 0.0 90 3.7 0.0 4.2 4 0 0 4 4 4 0 HEAT-like repeat Astro_capsid PF03115.9 EGC34270.1 - 3.5 5.7 3.8 4.4 5.4 2.6 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor CDC45 PF02724.9 EGC34270.1 - 6.7 4.6 15.4 9.7 4.0 10.7 1.1 1 0 0 1 1 1 0 CDC45-like protein APC8 PF04049.8 EGC34271.1 - 2.1e-29 102.0 2.8 2.1e-29 102.0 2.0 1.8 1 1 0 1 1 1 1 Anaphase promoting complex subunit 8 / Cdc23 TPR_1 PF00515.23 EGC34271.1 - 9.4e-12 44.0 4.6 0.00033 20.1 0.0 4.4 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC34271.1 - 3.2e-09 35.9 3.9 0.05 13.5 0.0 4.8 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34271.1 - 7.8e-09 35.0 1.3 9.9e-07 28.3 0.4 4.2 4 1 1 5 5 5 3 TPR repeat TPR_8 PF13181.1 EGC34271.1 - 1e-08 34.3 5.4 0.0003 20.3 0.0 4.5 5 0 0 5 5 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC34271.1 - 2.6e-06 27.4 11.0 0.0029 17.6 0.2 4.3 2 1 1 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGC34271.1 - 1.9e-05 24.9 2.0 10 7.0 0.0 5.9 5 2 2 7 7 6 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC34271.1 - 0.00033 20.5 8.0 0.00077 19.3 0.2 3.9 3 2 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC34271.1 - 0.0016 18.7 11.8 4 8.1 0.0 6.0 6 0 0 6 6 5 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34271.1 - 0.002 18.7 3.7 4.4 8.0 0.0 5.0 5 2 2 7 7 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC34271.1 - 0.045 13.6 3.8 0.2 11.5 0.0 3.2 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat UPF0231 PF06062.6 EGC34271.1 - 0.058 13.2 4.1 2.2 8.2 0.0 2.9 3 1 0 3 3 3 0 Uncharacterised protein family (UPF0231) Folate_carrier PF01770.13 EGC34271.1 - 0.065 11.7 2.5 0.12 10.9 1.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier Gag_spuma PF03276.9 EGC34271.1 - 1.2 7.4 10.1 1.6 7.0 7.0 1.1 1 0 0 1 1 1 0 Spumavirus gag protein APC_CDC26 PF10471.4 EGC34271.1 - 2.4 8.9 20.2 2.7 8.7 12.4 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 UDPGP PF01704.13 EGC34273.1 - 1.5e-169 563.9 6.8 1.8e-169 563.7 4.7 1.0 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase STAT_alpha PF01017.15 EGC34273.1 - 0.055 13.1 2.4 0.38 10.4 0.1 2.3 2 0 0 2 2 2 0 STAT protein, all-alpha domain NTF2 PF02136.15 EGC34274.1 - 8.5e-09 35.8 0.3 8.5e-09 35.8 0.2 1.9 2 0 0 2 2 2 1 Nuclear transport factor 2 (NTF2) domain RRM_1 PF00076.17 EGC34274.1 - 5e-08 32.4 0.1 1.3e-07 31.1 0.1 1.7 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34274.1 - 1.7e-07 30.9 0.1 4.1e-07 29.7 0.1 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34274.1 - 2.3e-07 30.6 0.0 7.3e-07 29.0 0.0 1.9 1 1 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC34274.1 - 0.011 15.5 1.1 0.011 15.5 0.8 3.5 4 0 0 4 4 4 0 RNA binding motif VWA_2 PF13519.1 EGC34275.1 - 1.2e-08 35.3 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA PF00092.23 EGC34275.1 - 1e-05 25.3 0.2 1e-05 25.3 0.1 2.8 2 1 1 3 3 3 1 von Willebrand factor type A domain DUF2228 PF10228.4 EGC34275.1 - 0.0013 18.3 4.0 0.0027 17.3 2.8 1.4 1 0 0 1 1 1 1 Uncharacterised conserved protein (DUF2228) DUF501 PF04417.7 EGC34275.1 - 0.28 11.0 3.8 0.72 9.6 2.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF501) zf-TRAF PF02176.13 EGC34276.1 - 2.8e-12 46.8 20.0 2.3e-08 34.2 3.3 4.5 2 2 2 4 4 4 2 TRAF-type zinc finger MATH PF00917.21 EGC34276.1 - 0.00015 21.9 0.7 0.00015 21.9 0.5 2.0 2 0 0 2 2 2 1 MATH domain zf-C3HC4_2 PF13923.1 EGC34276.1 - 0.0052 16.7 11.0 0.0052 16.7 7.6 3.8 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC34276.1 - 0.0061 16.2 5.9 0.0061 16.2 4.1 3.4 3 2 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC34276.1 - 0.012 15.2 2.0 0.012 15.2 1.4 3.4 1 1 2 3 3 3 0 Seven in absentia protein family zf-U11-48K PF05253.7 EGC34276.1 - 0.28 10.9 6.2 12 5.6 0.0 4.3 5 0 0 5 5 5 0 U11-48K-like CHHC zinc finger EF-hand_7 PF13499.1 EGC34277.1 - 1.7e-09 37.6 0.0 2.4e-09 37.1 0.0 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGC34277.1 - 4.3e-09 35.4 0.0 6.7e-05 22.4 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_1 PF00036.27 EGC34277.1 - 2e-08 32.9 0.0 0.00043 19.3 0.0 2.1 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGC34277.1 - 4.5e-08 32.5 0.0 0.004 16.7 0.0 2.1 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC34277.1 - 6.7e-06 25.2 0.0 0.0067 15.7 0.0 2.1 2 0 0 2 2 2 2 EF hand CH PF00307.26 EGC34278.1 - 1.1e-66 221.6 0.1 4.6e-17 62.0 0.0 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain EF-hand_1 PF00036.27 EGC34278.1 - 3.3e-15 54.1 5.4 1.6e-08 33.2 0.1 3.1 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGC34278.1 - 1.1e-13 51.1 0.4 3.3e-13 49.5 0.3 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGC34278.1 - 4.4e-12 44.8 0.3 7.5e-06 25.4 0.1 3.0 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGC34278.1 - 5.1e-12 45.2 2.8 3.5e-11 42.5 0.3 2.4 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC34278.1 - 1.8e-10 39.6 6.0 0.00013 21.1 0.2 3.3 3 0 0 3 3 3 2 EF hand CAMSAP_CH PF11971.3 EGC34278.1 - 6.2e-05 22.5 0.0 1.1 8.9 0.0 3.7 4 1 0 4 4 4 2 CAMSAP CH domain EF-hand_9 PF14658.1 EGC34278.1 - 0.00017 21.4 0.0 0.00035 20.4 0.0 1.5 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EGC34278.1 - 0.029 14.4 0.0 0.068 13.2 0.0 1.6 1 0 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Nbas_N PF15492.1 EGC34279.1 - 2.9e-11 42.9 0.2 2.7e-07 29.9 0.0 3.3 2 1 1 3 3 3 2 Neuroblastoma-amplified sequence, N terminal WD40 PF00400.27 EGC34279.1 - 0.012 15.4 0.7 2.3 8.2 0.0 3.5 3 0 0 3 3 3 0 WD domain, G-beta repeat HAMP PF00672.20 EGC34280.1 - 1.9e-105 345.1 20.8 4.9e-08 33.0 0.0 13.0 13 0 0 13 13 13 12 HAMP domain Response_reg PF00072.19 EGC34280.1 - 1.9e-34 118.0 0.6 4.3e-28 97.5 0.3 2.8 2 0 0 2 2 2 2 Response regulator receiver domain HATPase_c PF02518.21 EGC34280.1 - 1.2e-30 105.5 0.1 3.3e-30 104.0 0.1 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HisKA PF00512.20 EGC34280.1 - 8.2e-21 73.7 0.1 3.7e-20 71.6 0.0 2.3 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain HTH_6 PF01418.12 EGC34280.1 - 1.7e-08 34.0 13.4 44 3.8 0.0 10.9 11 0 0 11 11 11 0 Helix-turn-helix domain, rpiR family SpoIIID PF12116.3 EGC34280.1 - 1.9e-08 34.0 6.1 7.5 6.5 0.0 9.9 11 0 0 11 11 11 1 Stage III sporulation protein D PsbH PF00737.15 EGC34280.1 - 1.6e-07 30.7 0.1 77 2.9 0.0 9.3 11 0 0 11 11 11 0 Photosystem II 10 kDa phosphoprotein DUF2365 PF10157.4 EGC34280.1 - 0.0001 22.2 26.7 33 4.3 0.0 12.4 11 2 1 12 12 12 0 Uncharacterized conserved protein (DUF2365) DUF948 PF06103.6 EGC34280.1 - 0.072 12.9 73.5 6.9 6.6 0.3 16.1 4 4 7 15 15 15 0 Bacterial protein of unknown function (DUF948) LINES_N PF14694.1 EGC34282.1 - 1.1e-14 54.4 3.1 1.1e-14 54.4 2.2 2.3 2 1 1 3 3 3 1 Lines N-terminus LINES_C PF14695.1 EGC34282.1 - 0.00015 20.9 0.6 0.00032 19.8 0.4 1.6 1 0 0 1 1 1 1 Lines C-terminus PRK PF00485.13 EGC34282.1 - 0.042 13.4 0.3 0.093 12.2 0.2 1.5 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family UreE_N PF02814.10 EGC34283.1 - 0.087 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 UreE urease accessory protein, N-terminal domain SpecificRecomb PF10136.4 EGC34283.1 - 0.13 10.3 0.1 0.17 9.8 0.1 1.1 1 0 0 1 1 1 0 Site-specific recombinase Ank_2 PF12796.2 EGC34284.1 - 2.5e-59 197.5 12.3 7.9e-16 58.1 0.1 4.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) GDPD PF03009.12 EGC34284.1 - 1.8e-57 194.8 3.2 3.9e-57 193.6 0.0 2.9 2 1 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family Ank_4 PF13637.1 EGC34284.1 - 1.2e-34 118.0 1.7 2.4e-06 27.8 0.1 6.0 4 1 1 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EGC34284.1 - 3.1e-34 115.0 2.1 5.6e-06 25.8 0.0 8.7 8 0 0 8 8 8 6 Ankyrin repeat Ank_5 PF13857.1 EGC34284.1 - 1e-25 89.1 2.9 1.7e-09 37.5 0.1 6.7 4 1 2 6 6 6 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC34284.1 - 3.9e-25 85.4 8.7 0.0078 16.3 0.0 9.5 8 1 0 8 8 8 7 Ankyrin repeat CBM_20 PF00686.14 EGC34284.1 - 3.8e-16 58.4 0.4 1.1e-15 56.9 0.0 2.0 2 0 0 2 2 2 1 Starch binding domain SPX PF03105.14 EGC34284.1 - 8.2e-09 35.6 11.5 8.2e-09 35.6 8.0 4.8 3 2 1 4 4 4 1 SPX domain Band_7 PF01145.20 EGC34285.1 - 5e-27 94.9 0.2 7.1e-27 94.4 0.1 1.2 1 0 0 1 1 1 1 SPFH domain / Band 7 family Med2 PF11214.3 EGC34285.1 - 0.0028 17.6 1.1 0.0044 17.0 0.8 1.3 1 0 0 1 1 1 1 Mediator complex subunit 2 Terpene_synth PF01397.16 EGC34285.1 - 0.01 15.2 0.0 0.02 14.2 0.0 1.5 1 1 0 1 1 1 0 Terpene synthase, N-terminal domain CBM49 PF09478.5 EGC34286.1 - 4.4e-16 58.7 0.2 6.2e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TAXi_N PF14543.1 EGC34286.1 - 0.035 14.0 0.6 0.038 13.9 0.4 1.2 1 0 0 1 1 1 0 Xylanase inhibitor N-terminal PepSY_TM_3 PF13706.1 EGC34286.1 - 0.37 10.2 1.7 0.57 9.6 1.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix Hexapep PF00132.19 EGC34287.1 - 2e-17 61.8 10.7 1.1e-07 31.0 0.2 4.2 3 1 1 4 4 4 4 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGC34287.1 - 1.2e-09 37.5 9.1 0.0001 21.7 1.4 3.5 2 1 2 4 4 4 3 Hexapeptide repeat of succinyl-transferase Fucokinase PF07959.7 EGC34287.1 - 0.11 11.0 0.2 0.37 9.2 0.1 1.8 1 1 1 2 2 2 0 L-fucokinase Cpn10 PF00166.16 EGC34288.1 - 0.00068 19.5 0.0 0.00078 19.3 0.0 1.1 1 0 0 1 1 1 1 Chaperonin 10 Kd subunit AHSP PF09236.5 EGC34288.1 - 0.05 13.8 0.0 0.065 13.4 0.0 1.2 1 0 0 1 1 1 0 Alpha-haemoglobin stabilising protein PGK PF00162.14 EGC34289.1 - 4e-153 509.5 0.8 4.6e-153 509.3 0.5 1.0 1 0 0 1 1 1 1 Phosphoglycerate kinase DNA_mis_repair PF01119.14 EGC34291.1 - 1.3e-30 105.2 0.8 3.6e-30 103.8 0.2 2.0 2 0 0 2 2 2 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGC34291.1 - 1.2e-11 44.4 0.0 1.2e-11 44.4 0.0 2.9 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC34291.1 - 1.2e-09 37.8 0.1 1.8e-08 34.0 0.0 2.7 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase FNIP PF05725.7 EGC34292.1 - 2.1e-33 113.9 25.6 4.1e-10 39.4 0.9 6.6 3 2 3 7 7 7 7 FNIP Repeat LRR_1 PF00560.28 EGC34292.1 - 0.045 13.7 7.9 0.2 11.8 0.1 5.0 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_6 PF13516.1 EGC34292.1 - 0.069 13.2 9.2 0.21 11.7 0.1 4.8 6 1 0 6 6 6 0 Leucine Rich repeat LRR_7 PF13504.1 EGC34292.1 - 0.13 12.5 7.3 1.3 9.5 0.2 5.1 5 0 0 5 5 5 0 Leucine rich repeat EGF_2 PF07974.8 EGC34293.1 - 0.013 15.6 10.9 0.029 14.5 7.5 1.6 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.8 EGC34294.1 - 2.2e-05 24.5 29.5 0.00034 20.7 7.6 2.9 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC34294.1 - 0.0089 16.0 10.1 0.045 13.8 1.2 3.0 2 0 0 2 2 2 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC34294.1 - 4.6 7.2 26.6 2.4 8.1 5.7 3.1 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) Brix PF04427.13 EGC34295.1 - 2.6e-37 128.3 1.0 3.7e-37 127.8 0.7 1.2 1 0 0 1 1 1 1 Brix domain Pneumo_phosprot PF02478.11 EGC34295.1 - 4.7 6.6 7.3 0.61 9.5 2.2 1.5 2 0 0 2 2 2 0 Pneumovirus phosphoprotein LSM PF01423.17 EGC34296.1 - 7.2e-15 54.2 0.7 7.9e-15 54.1 0.5 1.0 1 0 0 1 1 1 1 LSM domain DUF4047 PF13256.1 EGC34297.1 - 0.0026 17.7 1.9 0.0026 17.7 1.3 2.7 2 1 1 3 3 3 1 Domain of unknown function (DUF4047) Tape_meas_lam_C PF09718.5 EGC34297.1 - 0.011 15.5 1.2 0.018 14.9 0.1 1.8 2 0 0 2 2 2 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) UPF0122 PF04297.9 EGC34297.1 - 0.065 13.2 4.1 0.14 12.2 2.5 1.9 1 1 0 1 1 1 0 Putative helix-turn-helix protein, YlxM / p13 like Ceramidase PF05875.7 EGC34298.1 - 8e-64 215.3 15.6 9.6e-64 215.0 10.8 1.1 1 0 0 1 1 1 1 Ceramidase DUF4117 PF13491.1 EGC34298.1 - 0.8 9.1 5.5 5.9 6.3 3.6 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4117) MRAP PF15183.1 EGC34298.1 - 9.9 5.8 9.6 2.7 7.6 3.1 2.7 2 1 0 2 2 2 0 Melanocortin-2 receptor accessory protein family Glycos_transf_2 PF00535.21 EGC34299.1 - 2.2e-27 95.7 0.1 3e-27 95.3 0.1 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGC34299.1 - 1.1e-09 38.4 0.0 1.8e-09 37.7 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGC34299.1 - 2.4e-08 33.4 0.1 3.3e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 DUF1449 PF07290.6 EGC34299.1 - 0.027 13.8 1.6 0.047 13.0 1.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1449) Glyco_tranf_2_4 PF13704.1 EGC34299.1 - 0.14 12.5 0.0 0.26 11.6 0.0 1.6 1 1 0 1 1 1 0 Glycosyl transferase family 2 DNA_methylase PF00145.12 EGC34300.1 - 2.1e-42 145.4 6.2 2.4e-42 145.2 4.3 1.0 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase DUF2951 PF11166.3 EGC34300.1 - 0.062 13.1 2.5 0.2 11.5 1.8 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) Methyltransf_12 PF08242.7 EGC34300.1 - 0.21 12.1 1.3 9.3 6.7 0.6 2.5 2 0 0 2 2 2 0 Methyltransferase domain zf-rbx1 PF12678.2 EGC34301.1 - 6.3e-34 115.9 13.9 7.5e-34 115.6 9.6 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGC34301.1 - 2.1e-17 62.7 10.1 2.7e-17 62.3 7.0 1.1 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_2 PF13639.1 EGC34301.1 - 1.9e-07 30.7 12.4 1.3e-06 28.1 8.6 2.0 1 1 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC34301.1 - 0.00073 19.1 12.4 0.017 14.7 8.6 2.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC34301.1 - 0.0025 17.4 10.6 0.0068 16.0 3.2 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC34301.1 - 0.017 15.1 13.0 0.74 9.8 9.2 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) FANCL_C PF11793.3 EGC34301.1 - 0.11 12.4 8.8 1.2 9.0 6.4 2.1 1 1 1 2 2 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EGC34301.1 - 0.54 10.0 12.8 6.1 6.6 8.9 2.5 1 1 0 1 1 1 0 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC34301.1 - 0.89 9.3 7.4 23 4.8 5.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-HC5HC2H PF13771.1 EGC34301.1 - 1.2 9.3 10.7 59 3.8 6.9 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain zf-HC5HC2H_2 PF13832.1 EGC34301.1 - 2.7 8.0 11.0 9 6.3 7.7 1.9 1 1 0 1 1 1 0 PHD-zinc-finger like domain Crystall_3 PF08964.5 EGC34302.1 - 0.0012 18.4 0.9 0.0018 17.9 0.6 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin SLT PF01464.15 EGC34303.1 - 8.2e-13 47.9 0.0 9.6e-13 47.6 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 EGC34303.1 - 0.01 15.8 1.6 0.064 13.2 1.1 1.9 1 1 0 1 1 1 0 C-type lysozyme/alpha-lactalbumin family Tim17 PF02466.14 EGC34304.1 - 8.6e-32 109.8 2.2 1.2e-31 109.4 1.5 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Gly-zipper_OmpA PF13436.1 EGC34304.1 - 0.0094 15.6 0.3 0.02 14.5 0.2 1.5 1 0 0 1 1 1 1 Glycine-zipper containing OmpA-like membrane domain CstA PF02554.9 EGC34304.1 - 0.025 13.2 0.1 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Carbon starvation protein CstA G0-G1_switch_2 PF15103.1 EGC34304.1 - 0.034 14.3 2.6 0.065 13.4 1.8 1.5 1 0 0 1 1 1 0 G0/G1 switch protein 2 DUF1517 PF07466.6 EGC34304.1 - 0.076 11.9 1.7 0.11 11.5 1.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF3947 PF13135.1 EGC34304.1 - 0.09 12.9 1.0 0.15 12.2 0.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3947) Peptidase_S49_N PF08496.5 EGC34304.1 - 0.15 11.8 5.0 0.19 11.5 3.5 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal ATP-synt_E PF05680.7 EGC34304.1 - 0.17 11.8 9.7 0.34 10.9 6.7 1.5 1 0 0 1 1 1 0 ATP synthase E chain DUF755 PF05501.6 EGC34304.1 - 1.7 8.7 13.3 2.4 8.2 9.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF755) Bacteriocin_IIc PF10439.4 EGC34304.1 - 9.1 6.4 10.9 0.15 12.2 1.3 2.2 3 0 0 3 3 3 0 Bacteriocin class II with double-glycine leader peptide Ribonucleas_3_3 PF14622.1 EGC34305.1 - 7.4e-37 126.1 0.0 2e-19 69.7 0.0 2.8 2 0 0 2 2 2 2 Ribonuclease-III-like Ribonuclease_3 PF00636.21 EGC34305.1 - 8.8e-33 113.1 0.0 4.5e-19 68.9 0.0 4.8 4 1 0 4 4 4 2 Ribonuclease III domain dsrm PF00035.20 EGC34305.1 - 1.2e-14 54.5 0.1 3.5e-14 53.1 0.0 1.9 1 0 0 1 1 1 1 Double-stranded RNA binding motif DND1_DSRM PF14709.1 EGC34305.1 - 0.058 13.6 0.0 0.13 12.5 0.0 1.6 1 0 0 1 1 1 0 double strand RNA binding domain from DEAD END PROTEIN 1 Surfac_D-trimer PF09006.6 EGC34305.1 - 5.2 6.8 9.4 0.064 12.9 0.3 2.4 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation IncA PF04156.9 EGC34305.1 - 7.7 6.0 16.2 0.24 10.9 3.8 2.3 2 0 0 2 2 2 0 IncA protein Claudin_3 PF06653.6 EGC34306.1 - 0.0011 18.7 13.2 0.0022 17.7 8.5 1.8 1 1 1 2 2 2 1 Tight junction protein, Claudin-like DUF898 PF05987.8 EGC34306.1 - 0.01 14.7 3.8 0.014 14.2 2.6 1.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) DUF3902 PF13042.1 EGC34306.1 - 0.011 14.9 4.4 0.011 14.9 3.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3902) ATP-synt_8 PF00895.15 EGC34306.1 - 2.9 8.1 16.1 2.2 8.5 1.2 3.2 3 0 0 3 3 3 0 ATP synthase protein 8 DUF3816 PF12822.2 EGC34306.1 - 8.3 6.2 15.1 2.1e+02 1.7 10.3 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) DUF202 PF02656.10 EGC34306.1 - 8.7 6.6 8.1 1.8 8.8 1.6 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF202) 2OG-FeII_Oxy_3 PF13640.1 EGC34307.1 - 1.4e-12 48.0 1.0 1.7e-12 47.6 0.2 1.5 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGC34307.1 - 2e-07 30.5 0.1 3.2e-07 29.9 0.1 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily PhyH PF05721.8 EGC34307.1 - 0.00068 19.7 0.0 0.73 9.8 0.0 2.2 1 1 1 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF552 PF04472.7 EGC34307.1 - 0.093 12.6 0.0 0.17 11.7 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF552) 2OG-FeII_Oxy_5 PF13759.1 EGC34307.1 - 0.2 11.9 2.0 0.75 10.1 0.3 2.6 2 1 0 2 2 2 0 Putative 2OG-Fe(II) oxygenase VWA_N PF08399.6 EGC34307.1 - 0.22 12.1 3.8 0.41 11.2 2.6 1.6 1 1 0 1 1 1 0 VWA N-terminal Ran_BP1 PF00638.13 EGC34308.1 - 1.1e-42 144.9 0.2 4.4e-42 142.9 0.0 1.8 1 1 1 2 2 2 1 RanBP1 domain WH1 PF00568.18 EGC34308.1 - 0.00032 20.4 0.2 0.0033 17.1 0.1 2.2 1 1 0 1 1 1 1 WH1 domain Rif1_N PF12231.3 EGC34309.1 - 3.6e-77 259.8 21.5 3.6e-77 259.8 14.9 2.5 3 0 0 3 3 3 1 Rap1-interacting factor 1 N terminal DNA_pol_A_exo1 PF01612.15 EGC34311.1 - 3.7e-46 156.8 0.4 8.2e-46 155.6 0.3 1.6 1 0 0 1 1 1 1 3'-5' exonuclease PMC2NT PF08066.7 EGC34311.1 - 1.4e-15 57.3 0.1 1.4e-15 57.3 0.1 3.6 5 0 0 5 5 5 1 PMC2NT (NUC016) domain HRDC PF00570.18 EGC34311.1 - 3.3e-13 49.1 0.0 9.1e-13 47.7 0.0 1.8 1 0 0 1 1 1 1 HRDC domain PAT1 PF09770.4 EGC34311.1 - 2.6 6.1 97.8 0.12 10.5 28.7 2.3 2 0 0 2 2 2 0 Topoisomerase II-associated protein PAT1 ketoacyl-synt PF00109.21 EGC34312.1 - 5.3e-62 209.5 0.0 1.2e-61 208.4 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34312.1 - 9.9e-47 159.8 0.0 1.9e-46 158.8 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34312.1 - 1.9e-32 111.5 0.0 5.8e-32 110.0 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC34312.1 - 1.7e-22 79.7 3.2 4.1e-22 78.5 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain KR PF08659.5 EGC34312.1 - 6.5e-22 78.0 0.0 1.4e-21 76.9 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC34312.1 - 3.6e-15 55.8 0.0 5.8e-15 55.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC34312.1 - 1.2e-14 54.5 0.0 2.4e-14 53.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC34312.1 - 8.6e-09 36.3 0.0 1.8e-08 35.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC34312.1 - 2.4e-07 30.4 0.0 5.9e-07 29.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC34312.1 - 2.6e-07 30.4 0.0 7.2e-07 29.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC34312.1 - 1.1e-06 29.0 0.0 8.4e-06 26.1 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC34312.1 - 6.9e-06 26.2 0.3 2.3e-05 24.5 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC34312.1 - 4.4e-05 22.5 0.0 9.2e-05 21.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC34312.1 - 5.5e-05 23.7 0.0 0.00019 22.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain ketoacyl-synt PF00109.21 EGC34313.1 - 1.4e-62 211.4 0.0 3.7e-62 210.0 0.0 1.8 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34313.1 - 5.3e-45 154.1 0.0 8.9e-45 153.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34313.1 - 2.8e-32 111.0 0.0 1.1e-31 109.1 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC34313.1 - 1.4e-23 83.2 3.9 1.8e-22 79.6 0.0 4.4 4 0 0 4 4 3 1 Methyltransferase domain KR PF08659.5 EGC34313.1 - 2.2e-22 79.6 0.0 4.9e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC34313.1 - 4.1e-15 56.0 0.0 7.7e-15 55.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EGC34313.1 - 6.2e-15 55.1 0.0 9.5e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC34313.1 - 7.9e-09 36.4 0.0 1.7e-08 35.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EGC34313.1 - 3.5e-08 33.8 0.0 3.4e-06 27.4 0.0 3.5 3 0 0 3 3 3 1 Methyltransferase domain ADH_N PF08240.7 EGC34313.1 - 2.8e-06 27.0 0.0 7.3e-06 25.7 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC34313.1 - 6.6e-06 25.9 0.0 2.2e-05 24.2 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34313.1 - 7e-06 26.5 0.0 2.4e-05 24.8 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC34313.1 - 1.5e-05 25.2 0.1 4.4e-05 23.6 0.1 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC34313.1 - 9.2e-05 21.5 0.1 0.00019 20.5 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC34314.1 - 1.1e-63 215.0 0.0 1.8e-63 214.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34314.1 - 2.5e-45 155.2 0.0 4.2e-45 154.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34314.1 - 9e-31 106.1 0.0 3.4e-30 104.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC34314.1 - 1.7e-22 79.9 0.0 3.7e-22 78.8 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC34314.1 - 9.8e-22 77.2 0.0 9.8e-22 77.2 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain PS-DH PF14765.1 EGC34314.1 - 3.3e-19 69.1 0.0 4.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC34314.1 - 1.8e-14 54.0 0.0 3.4e-14 53.1 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC34314.1 - 2.3e-07 31.7 0.0 5.3e-07 30.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC34314.1 - 1.1e-06 28.4 0.0 3.4e-06 26.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34314.1 - 2.5e-06 28.0 0.0 5.6e-05 23.6 0.0 2.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EGC34314.1 - 6.1e-06 25.9 0.1 1.5e-05 24.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC34314.1 - 6.6e-06 26.5 0.0 3.3e-05 24.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC34314.1 - 8.8e-06 24.8 0.0 1.9e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain PP-binding PF00550.20 EGC34314.1 - 0.00058 20.0 0.2 0.0017 18.5 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Pentapeptide_4 PF13599.1 EGC34317.1 - 8e-14 51.2 31.3 1.2e-10 41.0 10.4 2.5 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EGC34317.1 - 2.1e-05 24.2 10.1 2.1e-05 24.2 7.0 4.5 3 2 1 4 4 4 2 Pentapeptide repeats (9 copies) Pentapeptide PF00805.17 EGC34317.1 - 0.0001 21.4 4.7 0.013 14.7 0.2 3.4 3 0 0 3 3 3 2 Pentapeptide repeats (8 copies) zf-RING_2 PF13639.1 EGC34317.1 - 0.0011 18.7 7.4 0.0011 18.7 5.1 2.4 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC34317.1 - 0.0029 17.2 8.7 0.0029 17.2 6.0 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF1501 PF07394.7 EGC34317.1 - 5.5 5.7 23.0 9.7 4.9 16.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1501) FHIPEP PF00771.15 EGC34317.1 - 7.3 4.7 16.2 10 4.3 11.2 1.1 1 0 0 1 1 1 0 FHIPEP family ALMT PF11744.3 EGC34318.1 - 3e-31 108.4 8.4 3e-31 108.4 5.8 3.8 3 1 0 4 4 4 2 Aluminium activated malate transporter FUSC_2 PF13515.1 EGC34318.1 - 2.1e-12 47.0 23.7 8.5e-12 45.1 5.3 2.6 2 0 0 2 2 2 2 Fusaric acid resistance protein-like FUSC PF04632.7 EGC34318.1 - 0.00016 20.2 6.2 0.0004 18.9 4.3 1.6 1 0 0 1 1 1 1 Fusaric acid resistance protein family Rick_17kDa_Anti PF05433.10 EGC34318.1 - 0.11 12.1 0.1 0.24 11.0 0.1 1.6 1 0 0 1 1 1 0 Glycine zipper 2TM domain DUF1097 PF06496.6 EGC34318.1 - 5.5 6.8 20.4 0.42 10.4 5.6 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF1097) PAP_assoc PF03828.14 EGC34319.1 - 2.6e-06 27.2 0.3 2.6e-06 27.2 0.2 2.8 2 1 1 3 3 3 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGC34319.1 - 0.00029 21.0 0.3 0.0011 19.3 0.0 2.0 2 0 0 2 2 2 1 Nucleotidyltransferase domain Copper-fist PF00649.13 EGC34319.1 - 0.026 13.6 0.0 0.075 12.2 0.0 1.8 1 0 0 1 1 1 0 Copper fist DNA binding domain Carboxyl_trans PF01039.17 EGC34320.1 - 1.2e-162 541.6 0.1 1.4e-162 541.4 0.0 1.0 1 0 0 1 1 1 1 Carboxyl transferase domain MdcE PF06833.6 EGC34320.1 - 0.0015 17.7 0.0 0.059 12.5 0.0 2.3 2 0 0 2 2 2 1 Malonate decarboxylase gamma subunit (MdcE) ACCA PF03255.9 EGC34320.1 - 0.13 11.7 0.1 0.91 9.0 0.0 2.2 2 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit ketoacyl-synt PF00109.21 EGC34321.1 - 1.3e-63 214.8 0.0 3.8e-63 213.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34321.1 - 1.2e-48 166.0 0.0 1.8e-48 165.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34321.1 - 2e-32 111.5 0.0 1.3e-31 108.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGC34321.1 - 6.5e-12 45.2 0.0 1e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Thiolase_N PF00108.18 EGC34321.1 - 2e-06 27.0 0.1 4.4e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Glycos_transf_1 PF00534.15 EGC34322.1 - 6e-37 126.7 0.0 9.6e-37 126.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGC34322.1 - 7.8e-07 29.3 0.0 1.3e-06 28.6 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGC34322.1 - 0.00014 21.6 0.0 0.00033 20.4 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_4_4 PF13579.1 EGC34322.1 - 0.00097 19.3 0.0 0.0014 18.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGC34322.1 - 0.0049 17.0 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 7TM_GPCR_Str PF10326.4 EGC34323.1 - 0.0041 16.2 0.5 0.0087 15.2 0.4 1.5 1 0 0 1 1 1 1 Serpentine type 7TM GPCR chemoreceptor Str DUF1199 PF06712.6 EGC34323.1 - 0.05 13.4 0.0 14 5.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1199) DUF2975 PF11188.3 EGC34323.1 - 0.06 13.0 0.0 4.2 7.0 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2975) DUF1183 PF06682.7 EGC34323.1 - 0.13 11.8 7.2 0.0086 15.7 1.1 2.0 2 1 0 2 2 2 0 Protein of unknown function (DUF1183) DUF2615 PF11027.3 EGC34323.1 - 0.75 9.7 5.7 0.75 9.7 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2615) DUF912 PF06024.7 EGC34323.1 - 1.4 9.0 10.2 3.1 7.9 0.0 3.5 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) OATP PF03137.15 EGC34323.1 - 2 6.3 8.0 0.03 12.4 0.3 1.7 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family 7tm_1 PF00001.16 EGC34323.1 - 3.9 6.5 8.0 22 4.0 5.6 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DDHD PF02862.12 EGC34324.1 - 3e-29 102.4 12.6 3e-29 102.4 8.7 4.1 3 2 0 3 3 3 2 DDHD domain Abhydrolase_8 PF06259.7 EGC34324.1 - 0.027 13.9 0.0 0.063 12.7 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase Ribosomal_L32e PF01655.13 EGC34325.1 - 1.2e-43 147.6 0.5 1.6e-43 147.2 0.4 1.1 1 0 0 1 1 1 1 Ribosomal protein L32 RNA_pol_N PF01194.12 EGC34325.1 - 8.9e-29 99.3 1.7 1.5e-28 98.5 1.2 1.4 1 0 0 1 1 1 1 RNA polymerases N / 8 kDa subunit Lectin_leg-like PF03388.8 EGC34326.1 - 5.7e-64 215.3 0.3 5.7e-64 215.3 0.2 2.0 2 0 0 2 2 2 1 Legume-like lectin family Mitofilin PF09731.4 EGC34326.1 - 0.37 9.3 38.1 0.54 8.8 26.4 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Med15 PF09606.5 EGC34326.1 - 8.3 4.4 72.4 12 3.9 50.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal AA_permease_2 PF13520.1 EGC34327.1 - 2.1e-47 161.6 47.9 2.8e-47 161.2 33.2 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC34327.1 - 0.0089 14.4 42.2 0.058 11.7 29.3 2.2 1 1 0 1 1 1 1 Amino acid permease zf-SNAP50_C PF12251.3 EGC34328.1 - 3e-60 202.9 7.7 3.9e-60 202.6 5.4 1.1 1 0 0 1 1 1 1 snRNA-activating protein of 50kDa MW C terminal Defensin_4 PF07936.7 EGC34329.1 - 0.2 11.3 1.1 0.37 10.4 0.2 1.9 1 1 1 2 2 2 0 Potassium-channel blocking toxin PAP_fibrillin PF04755.7 EGC34330.1 - 0.087 12.5 1.2 0.13 12.0 0.8 1.3 1 0 0 1 1 1 0 PAP_fibrillin ecTbetaR2 PF08917.5 EGC34331.1 - 0.23 11.2 2.5 12 5.7 0.2 2.2 2 0 0 2 2 2 0 Transforming growth factor beta receptor 2 ectodomain TFIID_20kDa PF03847.8 EGC34332.1 - 6.4e-32 109.6 0.6 7.7e-32 109.4 0.4 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID subunit A Histone PF00125.19 EGC34332.1 - 0.0025 17.8 0.0 0.0034 17.4 0.0 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC34332.1 - 0.0049 16.8 0.1 0.0069 16.4 0.1 1.2 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone FCH PF00611.18 EGC34333.1 - 4.3e-19 68.4 0.2 4.3e-19 68.4 0.1 2.9 2 1 2 4 4 4 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_9 PF14604.1 EGC34333.1 - 7.2e-13 47.8 0.1 1.4e-12 47.0 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC34333.1 - 2.9e-11 42.5 0.1 5.4e-11 41.7 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC34333.1 - 2e-05 23.9 0.0 4.1e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain DUF3166 PF11365.3 EGC34333.1 - 0.021 15.2 2.2 0.054 13.9 1.0 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3166) Seryl_tRNA_N PF02403.17 EGC34333.1 - 0.022 14.7 13.3 0.11 12.5 0.2 2.5 1 1 1 2 2 2 0 Seryl-tRNA synthetase N-terminal domain TPR_MLP1_2 PF07926.7 EGC34333.1 - 0.043 13.5 16.3 0.3 10.8 2.5 2.7 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Syntaxin-18_N PF10496.4 EGC34333.1 - 0.047 13.5 3.4 0.19 11.5 2.4 2.1 1 0 0 1 1 1 0 SNARE-complex protein Syntaxin-18 N-terminus OmpH PF03938.9 EGC34333.1 - 0.08 12.8 9.7 0.18 11.7 6.7 1.5 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) Tropomyosin_1 PF12718.2 EGC34333.1 - 0.27 11.0 14.6 0.66 9.8 9.9 1.9 1 1 0 1 1 1 0 Tropomyosin like FlaC_arch PF05377.6 EGC34333.1 - 0.41 10.5 3.5 14 5.6 0.1 4.1 3 1 1 4 4 4 0 Flagella accessory protein C (FlaC) Streptin-Immun PF11083.3 EGC34333.1 - 4.3 7.3 12.8 10 6.1 0.4 3.5 1 1 2 3 3 3 0 Lantibiotic streptin immunity protein OTU PF02338.14 EGC34334.1 - 1.8e-10 41.4 0.1 1.8e-10 41.4 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC34334.1 - 0.46 8.6 58.5 0.58 8.3 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 CDC27 PF09507.5 EGC34334.1 - 0.78 8.8 36.9 1.1 8.4 25.6 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SAGA-Tad1 PF12767.2 EGC34334.1 - 6.5 6.3 26.5 12 5.4 18.4 1.4 1 0 0 1 1 1 0 Transcriptional regulator of RNA polII, SAGA, subunit DUF1748 PF08520.5 EGC34336.1 - 5.2e-08 32.4 0.0 7.6e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Fungal protein of unknown function (DUF1748) BAF1_ABF1 PF04684.8 EGC34336.1 - 0.001 18.0 6.7 0.0011 17.8 4.7 1.0 1 0 0 1 1 1 1 BAF1 / ABF1 chromatin reorganising factor YrpD PF15493.1 EGC34336.1 - 0.0078 15.8 0.3 0.0094 15.6 0.2 1.2 1 0 0 1 1 1 1 Domain of unknown function, YrpD Shisa PF13908.1 EGC34336.1 - 0.019 15.1 0.9 0.017 15.3 0.6 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator MSA-2c PF12238.3 EGC34336.1 - 0.026 14.1 3.3 0.029 14.0 2.3 1.1 1 0 0 1 1 1 0 Merozoite surface antigen 2c TSA PF03249.8 EGC34336.1 - 1.9 6.9 7.1 2 6.8 4.9 1.1 1 0 0 1 1 1 0 Type specific antigen Pex14_N PF04695.8 EGC34336.1 - 2.1 8.4 13.8 2.7 8.0 9.6 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region UCH PF00443.24 EGC34337.1 - 3.1e-60 203.5 1.7 3.1e-60 203.5 1.2 3.4 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC34337.1 - 2.3e-27 96.2 1.1 2.3e-27 96.2 0.7 4.2 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DIM PF08194.7 EGC34338.1 - 0.045 13.7 0.4 1.3 9.0 0.0 2.4 2 0 0 2 2 2 0 DIM protein SIS PF01380.17 EGC34339.1 - 5.5e-17 61.6 3.3 9.9e-11 41.3 0.5 2.3 2 0 0 2 2 2 2 SIS domain SIS_2 PF13580.1 EGC34339.1 - 1.4e-06 28.0 0.3 0.072 12.7 0.0 2.9 2 1 1 3 3 3 2 SIS domain Ribosomal_L32e PF01655.13 EGC34339.1 - 0.1 12.6 0.6 0.24 11.4 0.0 1.9 2 0 0 2 2 2 0 Ribosomal protein L32 Pkinase PF00069.20 EGC34340.1 - 2.2e-71 240.0 1.3 2.2e-71 240.0 0.9 3.1 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34340.1 - 5.3e-38 130.5 0.1 1.6e-37 128.9 0.1 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase POLO_box PF00659.13 EGC34340.1 - 2.1e-20 72.4 0.9 1.1e-13 50.9 0.1 4.2 5 0 0 5 5 5 2 POLO box duplicated region Plectin PF00681.15 EGC34340.1 - 0.0024 17.3 0.0 0.0064 15.9 0.0 1.8 1 0 0 1 1 1 1 Plectin repeat DUF3850 PF12961.2 EGC34340.1 - 0.041 13.8 5.2 0.12 12.3 0.0 3.2 3 0 0 3 3 3 0 Domain of Unknown Function with PDB structure (DUF3850) WD40 PF00400.27 EGC34341.1 - 3.2e-26 90.2 3.0 6.8e-07 28.9 0.0 5.4 5 1 0 5 5 5 4 WD domain, G-beta repeat Nup160 PF11715.3 EGC34341.1 - 4.6e-06 25.0 1.3 0.075 11.1 0.2 3.0 1 1 1 2 2 2 2 Nucleoporin Nup120/160 eIF2A PF08662.6 EGC34341.1 - 0.0024 17.6 1.3 0.2 11.3 0.2 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Coatomer_WDAD PF04053.9 EGC34341.1 - 0.023 13.5 2.9 0.03 13.1 1.3 1.6 1 1 1 2 2 2 0 Coatomer WD associated region Hira PF07569.6 EGC34341.1 - 0.029 13.5 0.3 1.9 7.6 0.0 2.8 3 1 0 3 3 3 0 TUP1-like enhancer of split RNA_pol_Rpc4 PF05132.9 EGC34341.1 - 0.07 13.1 0.0 1.2 9.1 0.0 2.2 2 0 0 2 2 2 0 RNA polymerase III RPC4 PQQ_2 PF13360.1 EGC34341.1 - 0.095 12.1 0.2 0.54 9.6 0.1 2.2 1 1 1 2 2 2 0 PQQ-like domain Methyltransf_23 PF13489.1 EGC34342.1 - 5.4e-25 87.9 0.0 1e-24 87.0 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34342.1 - 0.0055 17.1 0.3 0.031 14.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Elf1 PF05129.8 EGC34342.1 - 0.0059 16.2 4.7 0.0069 16.0 2.3 1.9 2 0 0 2 2 2 1 Transcription elongation factor Elf1 like zf-Mss51 PF13824.1 EGC34342.1 - 0.034 13.9 1.3 0.034 13.9 0.9 1.8 2 0 0 2 2 2 0 Zinc-finger of mitochondrial splicing suppressor 51 PolC_DP2 PF03833.8 EGC34342.1 - 0.1 10.2 1.1 0.14 9.7 0.7 1.1 1 0 0 1 1 1 0 DNA polymerase II large subunit DP2 Zn_Tnp_IS1595 PF12760.2 EGC34342.1 - 0.11 12.3 0.3 0.29 10.9 0.2 1.6 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Tnp_zf-ribbon_2 PF13842.1 EGC34342.1 - 2.7 8.4 5.4 17 5.9 3.7 2.4 1 1 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Acetyltransf_7 PF13508.1 EGC34343.1 - 1.2e-14 54.2 2.5 0.0021 18.2 0.0 4.7 4 0 0 4 4 4 4 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC34343.1 - 1.1e-10 41.3 0.0 0.012 15.5 0.0 4.5 4 0 0 4 4 4 3 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EGC34343.1 - 4.8e-07 29.5 0.0 0.1 12.4 0.0 4.3 4 0 0 4 4 4 2 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGC34343.1 - 3.8e-05 23.3 0.4 4 7.2 0.0 4.5 4 0 0 4 4 4 2 FR47-like protein Acetyltransf_10 PF13673.1 EGC34343.1 - 5.4e-05 23.2 0.0 2.5 8.2 0.0 4.3 4 0 0 4 4 4 1 Acetyltransferase (GNAT) domain Alpha_L_fucos PF01120.12 EGC34344.1 - 1.3e-110 369.5 7.5 1.8e-110 369.1 5.2 1.1 1 0 0 1 1 1 1 Alpha-L-fucosidase AhpC-TSA PF00578.16 EGC34345.1 - 1e-38 131.8 0.0 1.6e-38 131.1 0.0 1.3 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC34345.1 - 7.7e-18 64.4 0.0 9.6e-18 64.1 0.0 1.1 1 0 0 1 1 1 1 Redoxin 1-cysPrx_C PF10417.4 EGC34345.1 - 3.4e-10 39.4 0.0 8.8e-10 38.0 0.0 1.7 2 0 0 2 2 2 1 C-terminal domain of 1-Cys peroxiredoxin ATP-synt_A PF00119.15 EGC34346.1 - 0.0019 17.7 0.2 0.0027 17.2 0.2 1.1 1 0 0 1 1 1 1 ATP synthase A chain Erf4 PF10256.4 EGC34346.1 - 0.0066 16.3 1.8 0.035 13.9 1.2 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF423 PF04241.10 EGC34346.1 - 0.023 14.6 0.1 0.043 13.7 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF423) TMEM154 PF15102.1 EGC34346.1 - 0.067 12.9 0.7 0.14 11.8 0.5 1.5 1 0 0 1 1 1 0 TMEM154 protein family DUF2633 PF11119.3 EGC34346.1 - 0.11 12.2 0.6 0.11 12.2 0.4 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2633) ABC2_membrane PF01061.19 EGC34346.1 - 0.12 11.5 7.1 0.17 11.0 4.9 1.2 1 0 0 1 1 1 0 ABC-2 type transporter WAP PF00095.16 EGC34347.1 - 0.0053 16.6 5.9 0.0087 16.0 4.1 1.3 1 0 0 1 1 1 1 WAP-type (Whey Acidic Protein) 'four-disulfide core' Conotoxin PF02950.12 EGC34347.1 - 0.5 11.1 3.4 1 10.2 2.4 1.5 1 1 0 1 1 1 0 Conotoxin ATP-synt_8 PF00895.15 EGC34347.1 - 0.59 10.3 3.0 0.83 9.9 2.1 1.3 1 0 0 1 1 1 0 ATP synthase protein 8 tRNA-synt_2b PF00587.20 EGC34348.1 - 6.3e-47 159.3 0.4 1.4e-46 158.2 0.3 1.6 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC34348.1 - 8.3e-15 54.5 0.6 1.8e-14 53.4 0.4 1.6 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EGC34348.1 - 0.011 15.5 0.0 0.022 14.5 0.0 1.4 1 0 0 1 1 1 0 TGS domain zf-DHHC PF01529.15 EGC34349.1 - 1.6e-37 128.5 12.0 1.6e-37 128.5 8.3 2.8 2 1 1 3 3 3 1 DHHC palmitoyltransferase DZR PF12773.2 EGC34349.1 - 0.087 12.6 4.7 0.17 11.7 3.3 1.4 1 0 0 1 1 1 0 Double zinc ribbon WD40 PF00400.27 EGC34350.1 - 1.7e-25 87.8 6.0 3.3e-09 36.2 0.3 5.6 5 1 0 5 5 5 4 WD domain, G-beta repeat AIF_C PF14721.1 EGC34350.1 - 0.36 11.0 3.0 0.65 10.2 2.1 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term ABC2_membrane PF01061.19 EGC34351.1 - 2.6e-85 284.8 66.4 2e-48 164.3 14.8 2.6 3 0 0 3 3 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC34351.1 - 1.3e-38 132.3 0.0 7.5e-19 68.3 0.0 2.8 3 0 0 3 3 3 2 ABC transporter PDR_CDR PF06422.7 EGC34351.1 - 2.2e-22 78.6 17.3 1e-16 60.4 0.1 3.8 3 0 0 3 3 2 2 CDR ABC transporter ABC_trans_N PF14510.1 EGC34351.1 - 7.4e-12 45.1 0.0 2e-11 43.8 0.0 1.7 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal ABC2_membrane_3 PF12698.2 EGC34351.1 - 3.9e-07 29.4 22.9 3.9e-07 29.4 15.8 3.7 3 2 0 3 3 3 1 ABC-2 family transporter protein DUF258 PF03193.11 EGC34351.1 - 9.1e-07 28.2 0.1 3.5e-05 23.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC34351.1 - 1.4e-06 27.7 0.7 0.0029 17.1 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC34351.1 - 1.5e-05 24.5 0.0 0.00077 18.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC34351.1 - 0.00013 22.0 0.2 0.11 12.6 0.1 2.9 2 1 0 2 2 2 1 AAA domain cobW PF02492.14 EGC34351.1 - 0.00032 20.1 0.1 0.018 14.4 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_16 PF13191.1 EGC34351.1 - 0.0008 19.4 0.0 0.16 11.9 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_18 PF13238.1 EGC34351.1 - 0.0025 18.1 1.0 0.73 10.1 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_17 PF13207.1 EGC34351.1 - 0.0027 18.5 0.0 0.74 10.6 0.0 3.3 3 0 0 3 3 2 1 AAA domain AAA_21 PF13304.1 EGC34351.1 - 0.003 17.5 9.7 0.37 10.7 0.0 4.6 5 0 0 5 5 4 2 AAA domain AAA_33 PF13671.1 EGC34351.1 - 0.013 15.3 0.0 0.69 9.7 0.0 2.5 2 0 0 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGC34351.1 - 0.02 14.8 0.1 5.5 6.9 0.0 2.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase FtsK_SpoIIIE PF01580.13 EGC34351.1 - 0.021 14.3 0.1 2.6 7.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family SbcCD_C PF13558.1 EGC34351.1 - 0.023 14.6 0.0 0.32 10.9 0.0 2.5 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Arch_ATPase PF01637.13 EGC34351.1 - 0.033 13.8 0.7 2.4 7.7 0.0 2.7 3 0 0 3 3 2 0 Archaeal ATPase AAA PF00004.24 EGC34351.1 - 0.056 13.6 0.3 6.1 7.0 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Miro PF08477.8 EGC34351.1 - 0.068 13.6 0.0 4.5 7.7 0.0 2.7 2 0 0 2 2 2 0 Miro-like protein UPF0079 PF02367.12 EGC34351.1 - 0.11 12.1 0.4 0.71 9.5 0.1 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_23 PF13476.1 EGC34351.1 - 0.11 12.7 10.0 1.7 8.9 0.0 3.7 4 0 0 4 4 3 0 AAA domain AAA_19 PF13245.1 EGC34351.1 - 0.11 12.2 0.0 12 5.7 0.1 2.7 3 0 0 3 3 2 0 Part of AAA domain PduV-EutP PF10662.4 EGC34351.1 - 0.13 11.7 0.4 1.1 8.7 0.2 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation NACHT PF05729.7 EGC34351.1 - 0.14 11.8 0.5 4.6 6.8 0.2 2.4 2 0 0 2 2 2 0 NACHT domain NTPase_1 PF03266.10 EGC34351.1 - 0.18 11.4 0.4 39 3.9 0.0 3.2 3 0 0 3 3 3 0 NTPase AAA_28 PF13521.1 EGC34351.1 - 0.21 11.5 0.9 0.47 10.3 0.2 1.9 2 0 0 2 2 1 0 AAA domain AAA_30 PF13604.1 EGC34351.1 - 0.39 10.2 0.1 4.5 6.8 0.1 2.2 2 0 0 2 2 2 0 AAA domain 7TM_GPCR_Srx PF10328.4 EGC34352.1 - 0.022 13.8 1.0 0.022 13.8 0.7 1.0 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srx DUF4366 PF14283.1 EGC34353.1 - 0.013 14.9 0.8 0.015 14.7 0.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4366) DUF4528 PF15031.1 EGC34353.1 - 0.1 12.3 0.1 0.13 11.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4528) Glyco_hydro_38 PF01074.17 EGC34354.1 - 2e-66 224.0 3.8 3.3e-66 223.3 2.6 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGC34354.1 - 1.2e-22 80.3 6.3 2e-22 79.6 4.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGC34354.1 - 6.9e-17 61.4 0.0 1.9e-16 60.0 0.0 1.8 1 0 0 1 1 1 1 Alpha mannosidase, middle domain TIG PF01833.19 EGC34355.1 - 2.1e-18 66.0 29.9 3.4e-06 26.9 5.5 4.3 4 0 0 4 4 4 4 IPT/TIG domain Cupin_8 PF13621.1 EGC34356.1 - 2.1e-32 112.6 3.2 2.5e-32 112.3 2.2 1.0 1 0 0 1 1 1 1 Cupin-like domain JmjC PF02373.17 EGC34356.1 - 2.8e-09 37.1 0.1 6.3e-09 36.0 0.1 1.5 1 0 0 1 1 1 1 JmjC domain, hydroxylase Cupin_1 PF00190.17 EGC34356.1 - 0.018 14.4 0.0 0.038 13.4 0.0 1.6 1 1 0 1 1 1 0 Cupin Cupin_2 PF07883.6 EGC34356.1 - 0.05 13.1 0.0 0.13 11.7 0.0 1.6 2 0 0 2 2 2 0 Cupin domain Pox_polyA_pol_N PF12630.2 EGC34356.1 - 0.19 11.8 0.2 0.19 11.8 0.1 2.1 2 1 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain C2 PF00168.25 EGC34357.1 - 1.6e-16 59.9 0.0 3.2e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 C2 domain Methyltransf_2 PF00891.13 EGC34358.1 - 6.6e-46 156.4 0.0 8.7e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase DUF4448 PF14610.1 EGC34358.1 - 0.016 14.6 0.3 0.81 9.1 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4448) DUF3938 PF13074.1 EGC34358.1 - 0.038 13.8 0.7 0.098 12.5 0.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3938) Methyltransf_12 PF08242.7 EGC34358.1 - 0.045 14.2 0.1 0.27 11.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34358.1 - 0.048 14.2 0.0 0.1 13.1 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain YjgP_YjgQ PF03739.9 EGC34358.1 - 0.059 12.1 2.8 0.11 11.2 2.0 1.4 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family Methyltransf_31 PF13847.1 EGC34358.1 - 0.066 12.7 0.6 0.39 10.2 0.1 2.3 2 1 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGC34358.1 - 0.087 12.2 0.0 0.15 11.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain MpPF26 PF07666.6 EGC34358.1 - 0.1 12.4 4.8 0.21 11.4 3.3 1.4 1 0 0 1 1 1 0 M penetrans paralogue family 26 Abhydrolase_6 PF12697.2 EGC34359.1 - 1.9e-19 70.4 0.0 2.6e-19 70.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family PGAP1 PF07819.8 EGC34359.1 - 1.4e-12 47.6 0.1 2.3e-12 46.9 0.1 1.4 1 0 0 1 1 1 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGC34359.1 - 6.7e-11 42.1 0.0 1.3e-10 41.1 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34359.1 - 1.6e-10 40.9 0.1 1.2e-09 38.0 0.0 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydro_lipase PF04083.11 EGC34359.1 - 0.00015 21.0 0.2 0.03 13.6 0.0 2.4 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region DUF676 PF05057.9 EGC34359.1 - 0.00024 20.4 0.3 0.00044 19.6 0.2 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) Lipase_3 PF01764.20 EGC34359.1 - 0.00026 20.6 0.0 0.00045 19.8 0.0 1.5 1 0 0 1 1 1 1 Lipase (class 3) DUF2305 PF10230.4 EGC34359.1 - 0.0036 16.7 0.4 0.094 12.1 0.2 2.2 2 0 0 2 2 2 1 Uncharacterised conserved protein (DUF2305) Esterase PF00756.15 EGC34359.1 - 0.0045 16.4 0.0 0.0099 15.3 0.0 1.6 1 1 0 1 1 1 1 Putative esterase DUF1749 PF08538.5 EGC34359.1 - 0.0049 15.8 0.0 0.045 12.6 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1749) Cutinase PF01083.17 EGC34359.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.2 1 0 0 1 1 1 0 Cutinase BAAT_C PF08840.6 EGC34359.1 - 0.016 14.9 0.0 0.024 14.3 0.0 1.4 1 0 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Ndr PF03096.9 EGC34359.1 - 0.075 11.5 0.1 0.15 10.4 0.0 1.5 1 1 0 1 1 1 0 Ndr family Tim17 PF02466.14 EGC34361.1 - 1.7e-30 105.6 1.4 2.1e-30 105.3 1.0 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family SbcD_C PF12320.3 EGC34363.1 - 0.00063 19.7 1.8 0.00063 19.7 1.3 4.9 4 2 1 6 6 6 2 Type 5 capsule protein repressor C-terminal domain DUF948 PF06103.6 EGC34363.1 - 0.062 13.1 0.2 0.062 13.1 0.2 5.6 3 2 3 6 6 6 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EGC34363.1 - 0.3 10.6 32.2 0.015 14.9 8.6 3.6 3 1 0 3 3 3 0 IncA protein Phasin_2 PF09361.5 EGC34363.1 - 9.7 6.2 22.5 0.073 13.0 5.6 4.2 4 2 1 5 5 5 0 Phasin protein RA PF00788.18 EGC34364.1 - 7.3e-07 29.5 0.2 7.6e-07 29.5 0.1 1.2 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain PI3K_rbd PF00794.13 EGC34364.1 - 0.002 18.0 0.1 0.0021 17.9 0.1 1.2 1 0 0 1 1 1 1 PI3-kinase family, ras-binding domain FERM_N PF09379.5 EGC34364.1 - 0.016 15.2 0.1 0.017 15.1 0.0 1.1 1 0 0 1 1 1 0 FERM N-terminal domain Ras_bdg_2 PF14847.1 EGC34364.1 - 0.019 14.8 0.1 0.02 14.7 0.1 1.1 1 0 0 1 1 1 0 Ras-binding domain of Byr2 UN_NPL4 PF11543.3 EGC34364.1 - 0.031 14.5 0.1 0.037 14.3 0.1 1.1 1 0 0 1 1 1 0 Nuclear pore localisation protein NPL4 CH PF00307.26 EGC34365.1 - 1.9e-13 50.4 0.0 4.3e-13 49.2 0.0 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain DUF87 PF01935.12 EGC34365.1 - 1.4 8.6 4.6 3.1 7.5 3.2 1.5 1 0 0 1 1 1 0 Domain of unknown function DUF87 USP8_dimer PF08969.6 EGC34367.1 - 2.4e-26 91.9 3.6 2.4e-26 91.9 2.5 2.2 2 0 0 2 2 2 1 USP8 dimerisation domain JAB PF01398.16 EGC34367.1 - 8.9e-20 70.5 0.1 8.9e-20 70.5 0.1 2.1 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Prok-JAB PF14464.1 EGC34367.1 - 2.7e-07 30.1 0.0 5.2e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Prokaryotic homologs of the JAB domain ARGLU PF15346.1 EGC34367.1 - 0.0017 18.1 24.0 0.0033 17.2 16.6 1.4 1 0 0 1 1 1 1 Arginine and glutamate-rich 1 CAF-1_p150 PF11600.3 EGC34367.1 - 0.11 11.8 25.2 0.19 11.1 17.5 1.4 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal DDHD PF02862.12 EGC34367.1 - 0.17 11.6 4.0 0.28 10.9 2.8 1.4 1 0 0 1 1 1 0 DDHD domain U79_P34 PF03064.11 EGC34367.1 - 1.1 8.7 10.0 1.7 8.0 6.9 1.2 1 0 0 1 1 1 0 HSV U79 / HCMV P34 DUF3824 PF12868.2 EGC34367.1 - 3.6 8.5 6.8 8.1 7.3 4.7 1.6 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) SID-1_RNA_chan PF13965.1 EGC34369.1 - 4.6e-78 262.7 29.5 5.5e-78 262.5 20.4 1.0 1 0 0 1 1 1 1 dsRNA-gated channel SID-1 ATP-sulfurylase PF01747.12 EGC34370.1 - 2e-84 282.2 0.0 3e-84 281.6 0.0 1.3 1 0 0 1 1 1 1 ATP-sulfurylase APS_kinase PF01583.15 EGC34370.1 - 1.7e-60 203.2 0.0 3e-60 202.4 0.0 1.4 1 0 0 1 1 1 1 Adenylylsulphate kinase PUA_2 PF14306.1 EGC34370.1 - 1e-45 155.0 0.0 1.6e-45 154.3 0.0 1.3 1 0 0 1 1 1 1 PUA-like domain AAA_18 PF13238.1 EGC34370.1 - 4.6e-05 23.7 0.1 0.00014 22.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGC34370.1 - 5.5e-05 22.6 0.0 0.00012 21.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGC34370.1 - 6.6e-05 23.7 0.0 0.00022 22.0 0.0 2.0 2 0 0 2 2 1 1 AAA domain AAA_33 PF13671.1 EGC34370.1 - 0.00025 20.9 0.0 0.00049 19.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain KTI12 PF08433.5 EGC34370.1 - 0.0012 18.1 0.0 0.0019 17.4 0.0 1.4 1 0 0 1 1 1 1 Chromatin associated protein KTI12 MobB PF03205.9 EGC34370.1 - 0.0016 18.1 0.0 0.0034 17.0 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Zeta_toxin PF06414.7 EGC34370.1 - 0.0023 17.0 0.0 0.0053 15.8 0.0 1.6 2 0 0 2 2 2 1 Zeta toxin AAA_16 PF13191.1 EGC34370.1 - 0.0032 17.4 0.0 0.0062 16.5 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain ArgK PF03308.11 EGC34370.1 - 0.013 14.2 0.0 0.021 13.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein ABC_tran PF00005.22 EGC34370.1 - 0.015 15.5 0.1 0.044 14.0 0.0 1.7 2 0 0 2 2 1 0 ABC transporter Torsin PF06309.6 EGC34370.1 - 0.021 14.7 0.0 0.039 13.8 0.0 1.4 1 0 0 1 1 1 0 Torsin AAA_10 PF12846.2 EGC34370.1 - 0.023 14.1 0.1 0.053 12.9 0.1 1.6 2 0 0 2 2 2 0 AAA-like domain Sigma54_activat PF00158.21 EGC34370.1 - 0.027 13.9 0.0 0.047 13.1 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_28 PF13521.1 EGC34370.1 - 0.032 14.1 0.2 0.16 11.9 0.0 2.0 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC34370.1 - 0.048 12.8 0.0 0.083 12.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_30 PF13604.1 EGC34370.1 - 0.059 12.9 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGC34370.1 - 0.13 11.0 0.0 0.24 10.1 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain AAA_23 PF13476.1 EGC34370.1 - 0.14 12.4 0.2 0.25 11.6 0.1 1.4 1 0 0 1 1 1 0 AAA domain IIGP PF05049.8 EGC34370.1 - 0.17 10.6 0.0 0.29 9.9 0.0 1.3 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) T2SE PF00437.15 EGC34370.1 - 0.17 10.7 0.0 0.28 10.0 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein Sod_Cu PF00080.15 EGC34371.1 - 8.9e-18 64.8 0.3 2.1e-17 63.5 0.2 1.6 1 1 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) HMA PF00403.21 EGC34371.1 - 0.015 15.4 0.4 0.029 14.4 0.2 1.5 1 0 0 1 1 1 0 Heavy-metal-associated domain Aminotran_3 PF00202.16 EGC34373.1 - 7.9e-78 261.6 0.0 1.1e-77 261.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-III Beta_elim_lyase PF01212.16 EGC34373.1 - 0.062 12.4 0.0 0.11 11.6 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase HMGL-like PF00682.14 EGC34374.1 - 1.3e-57 195.2 0.0 1.6e-57 194.9 0.0 1.1 1 0 0 1 1 1 1 HMGL-like Med6 PF04934.9 EGC34375.1 - 1.8e-41 140.9 2.9 3e-41 140.2 2.0 1.4 1 0 0 1 1 1 1 MED6 mediator sub complex component MMR_HSR1_C PF08438.5 EGC34376.1 - 8.3e-33 112.8 0.0 1.7e-32 111.8 0.0 1.5 1 0 0 1 1 1 1 GTPase of unknown function C-terminal MMR_HSR1 PF01926.18 EGC34376.1 - 4.8e-18 65.2 0.0 1.3e-17 63.8 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC34376.1 - 8.2e-09 34.9 0.0 2.2e-07 30.2 0.0 2.4 2 0 0 2 2 2 1 Ferrous iron transport protein B TGS PF02824.16 EGC34376.1 - 0.0012 18.5 0.0 0.0026 17.5 0.0 1.5 1 0 0 1 1 1 1 TGS domain Dynamin_N PF00350.18 EGC34376.1 - 0.025 14.4 0.0 0.076 12.8 0.0 1.8 1 0 0 1 1 1 0 Dynamin family MMR_HSR1 PF01926.18 EGC34377.1 - 1.7e-06 27.9 2.3 9.7e-06 25.5 1.6 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC34377.1 - 2.2e-05 23.6 0.1 5.3e-05 22.4 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC34377.1 - 0.0044 16.4 0.0 0.0044 16.4 0.0 2.7 3 1 0 3 3 3 1 Elongation factor Tu GTP binding domain AAA_29 PF13555.1 EGC34377.1 - 0.012 15.1 0.0 0.034 13.6 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EGC34377.1 - 0.031 13.1 0.0 0.068 12.0 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein Miro PF08477.8 EGC34377.1 - 0.033 14.6 0.0 0.24 11.9 0.0 2.6 1 0 0 1 1 1 0 Miro-like protein MCM PF00493.18 EGC34377.1 - 0.034 12.9 2.8 0.043 12.6 0.0 2.5 3 0 0 3 3 3 0 MCM2/3/5 family MobB PF03205.9 EGC34377.1 - 0.042 13.5 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_17 PF13207.1 EGC34377.1 - 0.11 13.3 0.4 0.71 10.7 0.0 2.6 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGC34377.1 - 0.16 11.3 0.0 0.31 10.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AIG1 PF04548.11 EGC34377.1 - 0.32 10.0 12.8 0.88 8.6 0.0 3.8 4 0 0 4 4 4 0 AIG1 family Reo_sigmaC PF04582.7 EGC34378.1 - 3.5e-06 26.4 11.4 0.001 18.3 1.3 2.0 1 1 1 2 2 2 2 Reovirus sigma C capsid protein GAS PF13851.1 EGC34378.1 - 0.00019 20.7 41.2 0.0044 16.2 22.7 2.9 1 1 1 2 2 2 2 Growth-arrest specific micro-tubule binding DUF3584 PF12128.3 EGC34378.1 - 0.00023 18.7 25.3 0.00032 18.2 17.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) AAA_13 PF13166.1 EGC34378.1 - 0.00073 18.1 15.7 0.00073 18.1 10.9 2.5 1 1 1 2 2 2 1 AAA domain DUF3375 PF11855.3 EGC34378.1 - 0.0011 17.7 8.6 0.0035 16.1 2.6 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3375) DUF869 PF05911.6 EGC34378.1 - 0.0019 16.5 24.9 0.0024 16.1 17.2 1.1 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) DUF342 PF03961.8 EGC34378.1 - 0.002 16.5 9.8 0.002 16.5 6.8 2.8 1 1 2 3 3 3 1 Protein of unknown function (DUF342) IncA PF04156.9 EGC34378.1 - 0.01 15.4 33.6 16 5.0 23.3 2.7 1 1 0 1 1 1 0 IncA protein ADIP PF11559.3 EGC34378.1 - 0.012 15.5 10.0 0.012 15.5 6.9 2.6 2 1 0 2 2 2 0 Afadin- and alpha -actinin-Binding Bacillus_HBL PF05791.6 EGC34378.1 - 0.02 14.2 23.9 0.0086 15.4 13.8 2.4 1 1 1 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) Transcrip_act PF04949.8 EGC34378.1 - 0.02 14.5 18.3 0.065 12.8 2.6 2.9 1 1 1 2 2 2 0 Transcriptional activator DASH_Dad1 PF08649.5 EGC34378.1 - 0.028 14.1 6.6 0.14 11.8 0.5 4.0 3 1 0 3 3 3 0 DASH complex subunit Dad1 NPV_P10 PF05531.7 EGC34378.1 - 0.038 14.2 26.7 1.1 9.4 3.4 4.2 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein HrpB7 PF09486.5 EGC34378.1 - 0.097 12.5 10.9 0.11 12.4 2.8 2.6 1 1 1 2 2 2 0 Bacterial type III secretion protein (HrpB7) APG6 PF04111.7 EGC34378.1 - 0.1 11.6 33.9 0.13 11.3 9.1 2.3 1 1 1 2 2 2 0 Autophagy protein Apg6 WEMBL PF05701.6 EGC34378.1 - 0.11 10.9 31.6 0.25 9.7 18.1 2.0 1 1 1 2 2 2 0 Weak chloroplast movement under blue light EzrA PF06160.7 EGC34378.1 - 0.12 10.5 29.5 0.0093 14.1 14.2 2.1 1 1 0 2 2 2 0 Septation ring formation regulator, EzrA Fib_alpha PF08702.5 EGC34378.1 - 0.13 12.4 29.9 0.31 11.1 6.2 2.8 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Filament PF00038.16 EGC34378.1 - 0.14 11.5 31.0 0.19 11.1 14.0 2.9 1 1 1 2 2 2 0 Intermediate filament protein MCPsignal PF00015.16 EGC34378.1 - 0.18 11.3 15.4 0.34 10.4 3.0 2.4 1 1 1 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FUSC PF04632.7 EGC34378.1 - 0.22 9.9 0.8 0.25 9.7 0.5 1.1 1 0 0 1 1 1 0 Fusaric acid resistance protein family DivIVA PF05103.8 EGC34378.1 - 0.39 10.7 34.5 0.079 13.0 6.4 3.3 2 2 1 3 3 3 0 DivIVA protein DUF2968 PF11180.3 EGC34378.1 - 0.43 9.9 22.3 1.1 8.5 4.7 3.0 1 1 2 3 3 3 0 Protein of unknown function (DUF2968) Myosin_tail_1 PF01576.14 EGC34378.1 - 0.44 8.2 37.1 6.3 4.3 25.8 1.9 1 1 0 1 1 1 0 Myosin tail Occludin_ELL PF07303.8 EGC34378.1 - 0.5 11.1 19.1 0.14 12.9 3.4 3.5 1 1 2 3 3 3 0 Occludin homology domain DUF1664 PF07889.7 EGC34378.1 - 0.6 9.9 21.3 0.15 11.8 2.8 3.3 1 1 1 3 3 3 0 Protein of unknown function (DUF1664) Spc7 PF08317.6 EGC34378.1 - 0.71 8.4 39.1 4 6.0 9.8 2.9 1 1 1 2 2 2 0 Spc7 kinetochore protein Syntaxin PF00804.20 EGC34378.1 - 0.77 9.9 34.1 22 5.2 9.1 3.4 1 1 1 2 2 2 0 Syntaxin FlgN PF05130.7 EGC34378.1 - 0.92 9.7 24.6 1.4 9.1 7.4 2.4 1 1 1 2 2 2 0 FlgN protein Laminin_II PF06009.7 EGC34378.1 - 0.94 9.2 27.4 1.3 8.7 6.3 3.3 1 1 3 4 4 4 0 Laminin Domain II THOC7 PF05615.8 EGC34378.1 - 1 9.6 30.4 0.12 12.6 9.6 3.2 1 1 2 3 3 3 0 Tho complex subunit 7 TPR_MLP1_2 PF07926.7 EGC34378.1 - 1.1 9.0 36.3 2.8 7.7 11.8 3.2 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein ERM PF00769.14 EGC34378.1 - 1.1 8.7 31.5 0.46 9.9 9.9 2.2 1 1 0 2 2 2 0 Ezrin/radixin/moesin family ING PF12998.2 EGC34378.1 - 1.1 9.5 28.1 1 9.6 4.3 3.0 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding DUF4140 PF13600.1 EGC34378.1 - 1.2 9.5 19.5 1.4 9.4 0.5 3.9 1 1 2 4 4 3 0 N-terminal domain of unknown function (DUF4140) cwf21 PF08312.7 EGC34378.1 - 1.3 8.9 11.7 0.086 12.7 1.0 3.2 2 1 0 2 2 2 0 cwf21 domain FH2 PF02181.18 EGC34378.1 - 1.4 7.7 23.1 1.1 8.0 2.1 3.0 1 1 2 3 3 3 0 Formin Homology 2 Domain Mnd1 PF03962.10 EGC34378.1 - 1.4 8.5 29.7 3.5 7.2 6.4 2.5 1 1 1 2 2 2 0 Mnd1 family DUF4200 PF13863.1 EGC34378.1 - 1.8 8.5 36.1 0.13 12.2 12.0 3.3 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) Kinesin-relat_1 PF12711.2 EGC34378.1 - 1.8 8.9 30.0 0.5 10.8 1.0 4.2 2 2 2 4 4 4 0 Kinesin motor ATG16 PF08614.6 EGC34378.1 - 2 8.2 33.5 0.17 11.6 11.5 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) Prefoldin PF02996.12 EGC34378.1 - 2.2 7.9 30.1 2.2 7.9 3.3 4.6 2 1 3 5 5 5 0 Prefoldin subunit Laminin_I PF06008.9 EGC34378.1 - 2.6 7.3 32.2 0.85 8.8 19.4 1.8 1 1 1 2 2 2 0 Laminin Domain I DUF812 PF05667.6 EGC34378.1 - 2.9 6.3 29.6 5.3 5.4 8.5 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF812) Img2 PF05046.9 EGC34378.1 - 3 8.1 6.1 0.82 9.9 0.2 2.6 2 1 0 2 2 2 0 Mitochondrial large subunit ribosomal protein (Img2) Nsp1_C PF05064.8 EGC34378.1 - 3 7.4 25.7 7.3 6.2 5.4 2.9 1 1 1 2 2 2 0 Nsp1-like C-terminal region Syntaxin_2 PF14523.1 EGC34378.1 - 3.2 7.8 29.0 18 5.4 8.0 3.7 1 1 2 3 3 2 0 Syntaxin-like protein DUF3452 PF11934.3 EGC34378.1 - 3.4 7.0 9.8 3 7.1 2.5 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3452) PilJ PF13675.1 EGC34378.1 - 3.4 8.0 10.7 14 6.0 5.1 3.0 1 1 1 2 2 2 0 Type IV pili methyl-accepting chemotaxis transducer N-term Syntaxin-6_N PF09177.6 EGC34378.1 - 3.6 8.0 22.4 0.24 11.7 3.1 3.7 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Ndc1_Nup PF09531.5 EGC34378.1 - 3.7 5.8 5.3 4.5 5.5 3.7 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF4407 PF14362.1 EGC34378.1 - 3.8 6.3 20.4 2 7.2 12.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) HOOK PF05622.7 EGC34378.1 - 3.8 5.2 36.3 1.2 6.8 8.5 2.3 1 1 1 2 2 2 0 HOOK protein COG2 PF06148.6 EGC34378.1 - 4.1 7.2 19.3 7.4 6.4 0.2 4.0 1 1 3 4 4 4 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF641 PF04859.7 EGC34378.1 - 4.6 6.9 19.7 4.3 7.1 5.7 3.4 1 1 3 4 4 3 0 Plant protein of unknown function (DUF641) CENP-F_leu_zip PF10473.4 EGC34378.1 - 4.9 7.0 34.9 15 5.4 8.2 3.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 DUF4201 PF13870.1 EGC34378.1 - 5.2 6.4 35.4 0.33 10.3 13.7 3.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4201) V_ATPase_I PF01496.14 EGC34378.1 - 5.3 4.7 25.9 4 5.1 8.4 2.1 1 1 1 2 2 2 0 V-type ATPase 116kDa subunit family Seryl_tRNA_N PF02403.17 EGC34378.1 - 5.5 7.0 39.1 2.8 8.0 3.6 4.1 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain IFT57 PF10498.4 EGC34378.1 - 6.8 5.3 32.0 0.63 8.7 10.1 2.3 1 1 1 2 2 2 0 Intra-flagellar transport protein 57 Lectin_N PF03954.9 EGC34378.1 - 6.8 6.0 12.0 1.6 8.0 0.5 3.3 1 1 1 3 3 3 0 Hepatic lectin, N-terminal domain TMF_DNA_bd PF12329.3 EGC34378.1 - 7.3 6.4 47.6 0.99 9.2 9.4 4.6 1 1 4 5 5 5 0 TATA element modulatory factor 1 DNA binding DUF2746 PF10874.3 EGC34378.1 - 8.8 6.6 7.7 5.6 7.2 0.3 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF2746) Phage_GPO PF05929.6 EGC34378.1 - 9.7 5.3 18.1 0.85 8.8 4.0 2.2 1 1 0 2 2 2 0 Phage capsid scaffolding protein (GPO) serine peptidase DUF2365 PF10157.4 EGC34379.1 - 0.0022 17.8 6.7 0.024 14.5 0.1 3.1 2 1 1 3 3 3 1 Uncharacterized conserved protein (DUF2365) Uds1 PF15456.1 EGC34379.1 - 0.0024 17.8 10.9 0.052 13.5 2.3 3.4 2 2 1 3 3 3 1 Up-regulated During Septation Baculo_PEP_C PF04513.7 EGC34379.1 - 0.0049 16.7 2.2 0.0069 16.2 0.7 1.9 1 1 1 2 2 2 1 Baculovirus polyhedron envelope protein, PEP, C terminus HALZ PF02183.13 EGC34379.1 - 0.0085 15.7 2.8 0.048 13.3 0.1 3.2 3 0 0 3 3 3 1 Homeobox associated leucine zipper DUF869 PF05911.6 EGC34379.1 - 0.026 12.7 11.5 0.035 12.3 7.9 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) MCPsignal PF00015.16 EGC34379.1 - 0.039 13.5 0.3 0.08 12.4 0.1 1.6 1 1 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Tropomyosin_1 PF12718.2 EGC34379.1 - 0.043 13.6 14.6 0.016 15.0 6.4 2.6 1 1 1 2 2 2 0 Tropomyosin like Reo_sigmaC PF04582.7 EGC34379.1 - 0.049 12.8 0.2 0.063 12.4 0.1 1.1 1 0 0 1 1 1 0 Reovirus sigma C capsid protein Mnd1 PF03962.10 EGC34379.1 - 0.059 13.0 13.5 0.022 14.4 4.2 2.1 1 1 1 2 2 2 0 Mnd1 family Syntaxin-6_N PF09177.6 EGC34379.1 - 0.066 13.6 8.7 0.13 12.6 1.9 3.3 1 1 2 3 3 3 0 Syntaxin 6, N-terminal DUF948 PF06103.6 EGC34379.1 - 0.076 12.8 5.5 0.12 12.1 0.1 2.8 3 1 0 3 3 3 0 Bacterial protein of unknown function (DUF948) YjcZ PF13990.1 EGC34379.1 - 0.1 11.6 0.7 0.16 11.0 0.3 1.5 1 1 0 1 1 1 0 YjcZ-like protein Cluap1 PF10234.4 EGC34379.1 - 0.11 11.6 11.4 0.031 13.5 5.5 1.6 1 1 0 1 1 1 0 Clusterin-associated protein-1 ApoLp-III PF07464.6 EGC34379.1 - 0.12 12.3 6.5 0.12 12.4 3.2 2.0 1 1 0 1 1 1 0 Apolipophorin-III precursor (apoLp-III) DUF1664 PF07889.7 EGC34379.1 - 0.14 11.9 13.2 1.5 8.6 2.4 3.2 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) Nsp1_C PF05064.8 EGC34379.1 - 0.2 11.3 10.6 1.9 8.1 0.9 3.6 1 1 4 5 5 5 0 Nsp1-like C-terminal region RNase_HII PF01351.13 EGC34379.1 - 0.2 11.2 5.1 0.2 11.2 2.9 1.6 1 1 0 1 1 1 0 Ribonuclease HII GAS PF13851.1 EGC34379.1 - 0.21 10.7 19.4 0.018 14.2 7.7 2.2 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding Adeno_PIX PF03955.9 EGC34379.1 - 0.24 11.9 2.0 2.2 8.8 0.1 2.9 1 1 2 3 3 3 0 Adenovirus hexon-associated protein (IX) DUF3166 PF11365.3 EGC34379.1 - 0.37 11.2 5.1 0.085 13.3 1.0 1.9 2 1 0 2 2 1 0 Protein of unknown function (DUF3166) Lge1 PF11488.3 EGC34379.1 - 0.38 10.9 6.9 0.33 11.1 0.7 3.3 1 1 2 3 3 2 0 Transcriptional regulatory protein LGE1 ArsR PF09824.4 EGC34379.1 - 0.44 9.8 6.5 0.34 10.2 0.5 2.7 1 1 2 3 3 3 0 ArsR transcriptional regulator GvpK PF05121.7 EGC34379.1 - 0.48 10.2 8.0 0.059 13.1 0.7 2.8 3 1 0 3 3 3 0 Gas vesicle protein K Laminin_II PF06009.7 EGC34379.1 - 0.66 9.7 7.3 0.35 10.6 0.5 2.6 1 1 3 4 4 4 0 Laminin Domain II BLOC1_2 PF10046.4 EGC34379.1 - 0.77 9.9 16.0 0.42 10.7 3.0 3.8 1 1 3 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Fzo_mitofusin PF04799.8 EGC34379.1 - 1 8.7 6.3 1.2 8.5 2.5 2.4 1 1 1 2 2 2 0 fzo-like conserved region MtrG PF04210.8 EGC34379.1 - 1.1 8.9 5.0 1.5 8.5 0.0 2.9 2 1 1 3 3 3 0 Tetrahydromethanopterin S-methyltransferase, subunit G Viral_P18 PF04521.8 EGC34379.1 - 1.2 8.6 8.3 3.9 6.9 0.1 3.0 2 1 2 4 4 4 0 ssRNA positive strand viral 18kD cysteine rich protein ORF6C PF10552.4 EGC34379.1 - 1.4 8.6 7.5 0.11 12.2 0.6 2.5 2 2 2 4 4 2 0 ORF6C domain Occludin_ELL PF07303.8 EGC34379.1 - 1.6 9.5 13.0 2.8 8.7 2.8 3.4 2 1 1 3 3 3 0 Occludin homology domain CENP-F_leu_zip PF10473.4 EGC34379.1 - 1.6 8.5 19.2 0.1 12.4 6.4 2.8 1 1 2 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec34 PF04136.10 EGC34379.1 - 2.1 8.0 10.4 0.23 11.1 0.8 2.8 2 1 0 3 3 3 0 Sec34-like family V_ATPase_I PF01496.14 EGC34379.1 - 3.4 5.4 13.1 14 3.4 8.0 2.0 1 1 0 1 1 1 0 V-type ATPase 116kDa subunit family SseC PF04888.7 EGC34379.1 - 3.4 6.8 4.6 13 5.0 0.2 2.2 1 1 1 2 2 2 0 Secretion system effector C (SseC) like family DUF2120 PF09893.4 EGC34379.1 - 3.6 7.5 12.7 1.1 9.2 1.6 3.0 1 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2120) Fib_alpha PF08702.5 EGC34379.1 - 3.8 7.6 13.7 19 5.3 5.9 2.7 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family Vac_Fusion PF02346.11 EGC34379.1 - 4.3 6.8 8.9 2.5 7.6 0.3 3.3 2 1 0 3 3 3 0 Chordopoxvirus fusion protein Cauli_DNA-bind PF03310.8 EGC34379.1 - 4.7 7.0 9.2 6.9 6.5 0.4 3.3 1 1 3 4 4 4 0 Caulimovirus DNA-binding protein DUF2400 PF09674.5 EGC34379.1 - 5.7 6.5 9.6 3.6 7.2 0.9 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF2400) Syntaxin PF00804.20 EGC34379.1 - 6.6 6.9 14.3 1.4e+02 2.7 9.9 2.8 1 1 0 1 1 1 0 Syntaxin CALCOCO1 PF07888.6 EGC34379.1 - 6.8 4.8 13.0 0.87 7.7 5.9 1.7 1 1 0 2 2 2 0 Calcium binding and coiled-coil domain (CALCOCO1) like Snapin_Pallidin PF14712.1 EGC34379.1 - 8.3 6.8 10.0 1.9 8.8 0.9 3.0 1 1 2 3 3 3 0 Snapin/Pallidin CesA PF11439.3 EGC34380.1 - 0.035 14.0 0.4 0.082 12.8 0.3 1.6 1 0 0 1 1 1 0 Type III secretion system filament chaperone CesA RPA_C PF08784.6 EGC34380.1 - 0.85 10.0 7.4 0.53 10.7 1.6 2.4 2 0 0 2 2 2 0 Replication protein A C terminal CMAS PF02353.15 EGC34382.1 - 9.9e-86 287.1 0.6 1.3e-85 286.8 0.4 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGC34382.1 - 2.9e-10 40.1 0.0 8.2e-10 38.6 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34382.1 - 7.9e-09 36.0 0.0 3.2e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC34382.1 - 3.1e-08 33.9 0.0 8.8e-08 32.5 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34382.1 - 1.1e-06 28.3 0.0 2e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34382.1 - 9e-05 22.8 0.0 0.00023 21.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGC34382.1 - 0.0041 17.9 0.0 0.013 16.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGC34382.1 - 0.047 12.7 0.0 0.13 11.2 0.0 1.7 1 1 0 1 1 1 0 O-methyltransferase Methyltransf_26 PF13659.1 EGC34382.1 - 0.16 11.9 0.0 0.35 10.9 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain SAP30_Sin3_bdg PF13867.1 EGC34383.1 - 7e-20 70.6 0.3 1.2e-19 69.8 0.2 1.4 1 0 0 1 1 1 1 Sin3 binding region of histone deacetylase complex subunit SAP30 CDC48_2 PF02933.12 EGC34383.1 - 0.11 12.2 0.0 0.24 11.0 0.0 1.6 1 0 0 1 1 1 0 Cell division protein 48 (CDC48), domain 2 LRR_4 PF12799.2 EGC34384.1 - 3.9e-40 134.8 41.1 3.9e-09 35.9 2.3 6.4 3 2 2 6 6 6 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC34384.1 - 4.9e-26 90.2 48.2 8.7e-10 38.2 2.5 5.2 1 1 5 6 6 6 6 Leucine rich repeat LRR_9 PF14580.1 EGC34384.1 - 8.9e-23 80.7 19.3 1.4e-09 37.7 0.3 4.0 1 1 3 4 4 4 4 Leucine-rich repeat LRR_1 PF00560.28 EGC34384.1 - 4.5e-15 53.3 32.6 0.089 12.8 0.1 11.0 10 1 1 11 11 11 5 Leucine Rich Repeat LRR_6 PF13516.1 EGC34384.1 - 1.3e-11 43.2 34.3 0.012 15.5 0.3 10.6 7 2 4 11 11 11 3 Leucine Rich repeat LRR_7 PF13504.1 EGC34384.1 - 9.8e-10 37.0 21.5 0.46 10.9 0.1 10.3 7 3 2 9 9 9 3 Leucine rich repeat DcpS_C PF11969.3 EGC34384.1 - 0.48 10.6 2.5 2.4 8.4 0.3 2.6 2 2 1 3 3 3 0 Scavenger mRNA decapping enzyme C-term binding LRR_2 PF07723.8 EGC34384.1 - 0.73 10.4 5.2 45 4.7 0.0 4.9 5 0 0 5 5 5 0 Leucine Rich Repeat mIF3 PF14877.1 EGC34384.1 - 3.7 6.8 9.0 0.15 11.4 1.3 2.2 2 1 1 3 3 3 0 Mitochondrial translation initiation factor CBM49 PF09478.5 EGC34385.1 - 1.9e-16 59.9 0.0 2.6e-16 59.4 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Plant_vir_prot PF01307.12 EGC34386.1 - 4.7 6.9 5.6 30 4.3 3.9 2.0 1 1 0 1 1 1 0 Plant viral movement protein DUF726 PF05277.7 EGC34387.1 - 0.083 11.7 0.1 0.14 11.0 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF726) Snapin_Pallidin PF14712.1 EGC34388.1 - 6.9e-16 58.3 9.9 6.9e-16 58.3 6.9 2.9 3 0 0 3 3 3 1 Snapin/Pallidin Atg14 PF10186.4 EGC34388.1 - 0.67 8.8 20.4 0.93 8.3 14.2 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF4634 PF15465.1 EGC34388.1 - 3 8.0 5.8 1 9.5 0.8 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4634) zf-CCCH PF00642.19 EGC34389.1 - 2.1e-06 27.2 1.9 3.9e-06 26.3 1.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-RanBP PF00641.13 EGC34389.1 - 0.00012 21.1 1.3 0.00012 21.1 0.9 2.2 2 0 0 2 2 2 1 Zn-finger in Ran binding protein and others zf-MYND PF01753.13 EGC34389.1 - 0.0041 16.9 8.8 0.01 15.6 6.1 1.7 1 0 0 1 1 1 1 MYND finger RAP1 PF07218.6 EGC34390.1 - 2 6.4 10.0 1.8 6.5 6.9 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) PAPS_reduct PF01507.14 EGC34391.1 - 0.29 10.9 5.9 0.98 9.2 0.3 2.4 1 1 1 2 2 2 0 Phosphoadenosine phosphosulfate reductase family VWA PF00092.23 EGC34392.1 - 1.8e-05 24.5 0.7 0.11 12.1 0.1 2.7 1 1 1 2 2 2 2 von Willebrand factor type A domain Dynamin_N PF00350.18 EGC34392.1 - 0.016 15.0 1.8 1.8 8.3 0.1 2.9 2 0 0 2 2 2 0 Dynamin family VWA_2 PF13519.1 EGC34392.1 - 0.052 13.6 0.0 1.1 9.3 0.0 2.2 1 1 1 2 2 2 0 von Willebrand factor type A domain VWA_2 PF13519.1 EGC34393.1 - 1.2e-06 28.7 0.0 2e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Miro PF08477.8 EGC34393.1 - 0.0087 16.5 1.0 0.11 13.0 0.7 2.8 1 1 0 1 1 1 1 Miro-like protein vWA-TerF-like PF10138.4 EGC34393.1 - 0.021 14.6 0.7 2.2 8.0 0.0 2.5 2 1 0 2 2 2 0 vWA found in TerF C terminus Asn_synthase PF00733.16 EGC34394.1 - 8.7e-61 205.6 0.0 1.2e-60 205.2 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC34394.1 - 1.2e-44 151.0 0.0 1.8e-44 150.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC34394.1 - 2.9e-38 130.8 0.0 4.4e-38 130.2 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGC34394.1 - 3.8e-05 22.5 0.0 0.18 10.4 0.0 2.3 1 1 1 2 2 2 2 Glutamine amidotransferases class-II DUF3700 PF12481.3 EGC34394.1 - 6.9e-05 22.1 0.0 0.00013 21.2 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein NAD_synthase PF02540.12 EGC34394.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Cupin_8 PF13621.1 EGC34395.1 - 2.4e-49 168.0 3.8 5.8e-49 166.8 1.6 1.9 2 0 0 2 2 2 1 Cupin-like domain Cupin_4 PF08007.7 EGC34395.1 - 3.5e-12 46.1 0.0 7.7e-11 41.8 0.0 2.3 1 1 0 1 1 1 1 Cupin superfamily protein JmjC PF02373.17 EGC34395.1 - 0.00023 21.3 0.0 0.00091 19.4 0.0 2.2 1 1 0 1 1 1 1 JmjC domain, hydroxylase Cupin_2 PF07883.6 EGC34395.1 - 0.024 14.1 0.0 0.054 12.9 0.0 1.5 1 0 0 1 1 1 0 Cupin domain HSP20 PF00011.16 EGC34395.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Hsp20/alpha crystallin family ARD PF03079.9 EGC34395.1 - 0.19 11.6 1.2 0.67 9.8 0.0 2.4 3 0 0 3 3 3 0 ARD/ARD' family DUF1965 PF09248.5 EGC34395.1 - 0.2 11.5 1.5 0.35 10.8 0.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1965) Avidin PF01382.12 EGC34396.1 - 0.032 14.4 3.0 0.038 14.2 2.1 1.1 1 0 0 1 1 1 0 Avidin family SPC22 PF04573.7 EGC34398.1 - 6.4e-33 113.4 2.1 7.2e-33 113.2 1.4 1.0 1 0 0 1 1 1 1 Signal peptidase subunit DUF1179 PF06678.6 EGC34398.1 - 0.1 12.8 0.1 0.16 12.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1179) Pol_alpha_B_N PF08418.5 EGC34399.1 - 0.061 12.8 0.4 0.069 12.6 0.3 1.1 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal RGS PF00615.14 EGC34399.1 - 0.099 12.7 1.7 0.11 12.5 1.2 1.2 1 0 0 1 1 1 0 Regulator of G protein signaling domain Atg8 PF02991.11 EGC34400.1 - 2.2e-15 56.4 0.8 2.5e-15 56.3 0.5 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like HlyIII PF03006.15 EGC34402.1 - 1.5e-38 132.3 28.9 2.1e-38 131.9 20.0 1.1 1 0 0 1 1 1 1 Haemolysin-III related Gti1_Pac2 PF09729.4 EGC34402.1 - 0.77 9.6 5.3 1.2 8.9 3.7 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family Anticodon_1 PF08264.8 EGC34402.1 - 2.3 7.9 6.6 1.2 8.8 1.5 2.3 2 0 0 2 2 2 0 Anticodon-binding domain of tRNA DUF1664 PF07889.7 EGC34404.1 - 2.3 7.9 14.0 0.17 11.7 3.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Lebercilin PF15619.1 EGC34404.1 - 4.3 6.6 36.6 0.63 9.4 11.6 3.1 2 1 1 3 3 3 0 Ciliary protein causing Leber congenital amaurosis disease Tweety PF04906.8 EGC34404.1 - 7 4.9 6.0 2.5 6.4 1.6 2.0 1 1 0 1 1 1 0 Tweety EGF_2 PF07974.8 EGC34405.1 - 0.0035 17.4 11.4 0.0095 16.0 7.9 1.8 1 0 0 1 1 1 1 EGF-like domain TPR_11 PF13414.1 EGC34406.1 - 0.038 13.6 2.2 0.053 13.1 0.2 2.1 2 0 0 2 2 2 0 TPR repeat DUF2508 PF10704.4 EGC34407.1 - 0.0048 17.0 2.3 0.0083 16.2 0.4 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF2508) U5_2-snRNA_bdg PF10597.4 EGC34407.1 - 0.0087 15.6 1.2 0.024 14.2 0.0 2.3 2 1 0 2 2 2 1 U5-snRNA binding site 2 of PrP8 Peptidase_M28 PF04389.12 EGC34407.1 - 0.065 12.9 0.1 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 Peptidase family M28 Imm41 PF15583.1 EGC34407.1 - 0.4 10.4 5.5 1.3 8.8 1.3 2.9 2 1 0 2 2 2 0 Immunity protein 41 Ric8 PF10165.4 EGC34408.1 - 0.031 13.1 3.9 0.27 10.0 2.7 1.9 1 1 0 1 1 1 0 Guanine nucleotide exchange factor synembryn DUF2706 PF10913.3 EGC34408.1 - 0.052 13.1 1.8 0.16 11.6 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2706) Peptidase_C74 PF12387.3 EGC34408.1 - 0.057 12.5 1.6 0.076 12.1 1.0 1.5 1 1 0 1 1 1 0 Pestivirus NS2 peptidase HBS1_N PF08938.5 EGC34408.1 - 0.084 13.0 0.7 0.21 11.7 0.1 2.1 2 0 0 2 2 2 0 HBS1 N-terminus DUF1689 PF07954.6 EGC34408.1 - 0.17 11.7 1.5 0.26 11.1 0.5 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF1689) DUF1847 PF08901.6 EGC34409.1 - 0.014 14.9 0.0 0.02 14.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) DUF3890 PF13029.1 EGC34409.1 - 0.13 12.3 1.8 0.51 10.4 0.7 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF3890) RhoGAP PF00620.22 EGC34410.1 - 2.9e-47 160.0 0.1 1.4e-46 157.9 0.0 2.3 2 0 0 2 2 2 1 RhoGAP domain PH PF00169.24 EGC34410.1 - 1.4e-11 44.4 1.9 1.4e-11 44.4 1.3 2.6 2 1 0 2 2 2 1 PH domain SH3_9 PF14604.1 EGC34410.1 - 1.8e-07 30.5 0.2 3.7e-07 29.6 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC34410.1 - 3.1e-06 26.5 0.1 8.7e-06 25.1 0.0 1.8 2 0 0 2 2 2 1 Variant SH3 domain SH3_1 PF00018.23 EGC34410.1 - 9.1e-05 21.7 0.3 0.00022 20.5 0.2 1.7 1 0 0 1 1 1 1 SH3 domain FKBP_C PF00254.23 EGC34411.1 - 5e-26 90.5 0.0 5.5e-26 90.4 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RhoGAP PF00620.22 EGC34413.1 - 6e-36 123.3 0.0 1.6e-35 121.9 0.0 1.7 1 0 0 1 1 1 1 RhoGAP domain LRR_6 PF13516.1 EGC34413.1 - 6.1e-05 22.6 38.6 0.012 15.6 0.1 8.8 11 0 0 11 11 11 4 Leucine Rich repeat DEC-1_N PF04625.8 EGC34414.1 - 0.11 11.2 2.6 0.13 10.8 1.8 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Neisseria_TspB PF05616.8 EGC34414.1 - 1 7.6 3.5 1.3 7.2 2.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Phosphoprotein PF00922.12 EGC34414.1 - 6.5 5.8 7.8 7.6 5.6 5.4 1.1 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein Proteasome PF00227.21 EGC34415.1 - 6e-61 205.0 0.3 7.9e-61 204.6 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC34415.1 - 1.1e-15 56.6 0.1 2.2e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature DUF1669 PF07894.7 EGC34415.1 - 0.12 11.5 1.6 0.17 11.0 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1669) Exo70 PF03081.10 EGC34417.1 - 5.2e-48 163.6 14.8 1.2e-47 162.5 10.2 1.6 1 0 0 1 1 1 1 Exo70 exocyst complex subunit DASH_Dad2 PF08654.5 EGC34417.1 - 0.0047 16.8 0.6 0.023 14.6 0.4 2.3 1 0 0 1 1 1 1 DASH complex subunit Dad2 USP8_interact PF08941.5 EGC34417.1 - 0.032 13.5 1.0 0.15 11.3 0.5 2.1 2 0 0 2 2 2 0 USP8 interacting RhoGAP PF00620.22 EGC34418.1 - 7.1e-39 132.8 0.2 7.1e-39 132.8 0.1 2.4 3 0 0 3 3 3 1 RhoGAP domain DUF1192 PF06698.6 EGC34418.1 - 0.0034 17.1 0.7 0.38 10.6 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1192) Ribosomal_L29 PF00831.18 EGC34418.1 - 0.0087 15.7 1.4 1.2 8.8 0.1 2.8 2 0 0 2 2 2 2 Ribosomal L29 protein Vps5 PF09325.5 EGC34419.1 - 4e-57 193.1 9.4 8.8e-57 192.0 6.5 1.5 1 0 0 1 1 1 1 Vps5 C terminal like PX PF00787.19 EGC34419.1 - 2.1e-23 82.2 0.0 1e-22 80.0 0.0 2.3 2 0 0 2 2 2 1 PX domain BAR PF03114.13 EGC34419.1 - 0.0016 18.0 6.2 0.0039 16.7 4.3 1.6 1 0 0 1 1 1 1 BAR domain Streptin-Immun PF11083.3 EGC34419.1 - 2.8 7.9 7.8 0.44 10.5 1.7 2.5 2 1 1 3 3 3 0 Lantibiotic streptin immunity protein FNIP PF05725.7 EGC34420.1 - 4.9e-59 196.0 41.2 3.3e-13 49.3 0.2 7.7 6 1 3 9 9 9 8 FNIP Repeat LRR_5 PF13306.1 EGC34420.1 - 0.0015 18.2 10.8 0.44 10.2 0.3 4.5 1 1 1 4 4 4 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC34420.1 - 0.02 14.8 8.3 2.5 8.1 0.0 5.7 3 1 4 7 7 7 0 Protein of unknown function (DUF1769) SBDS_C PF09377.5 EGC34421.1 - 7.4e-40 135.5 3.1 7.4e-40 135.5 2.1 1.7 2 0 0 2 2 2 1 SBDS protein C-terminal domain SBDS PF01172.13 EGC34421.1 - 1.3e-31 108.2 1.5 3.1e-31 107.0 1.0 1.7 1 0 0 1 1 1 1 Shwachman-Bodian-Diamond syndrome (SBDS) protein Aminotran_1_2 PF00155.16 EGC34422.1 - 3.4e-12 45.9 0.0 4.6e-12 45.5 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_MocR PF12897.2 EGC34422.1 - 9.2e-05 21.1 0.0 0.00015 20.5 0.0 1.2 1 0 0 1 1 1 1 Alanine-glyoxylate amino-transferase LSM PF01423.17 EGC34423.1 - 1.1e-14 53.7 0.3 1.7e-14 53.0 0.2 1.3 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC34423.1 - 0.04 13.8 0.1 0.084 12.8 0.0 1.5 1 1 0 1 1 1 0 Ataxin 2 SM domain AAA PF00004.24 EGC34424.1 - 6.9e-12 45.7 0.2 2.6e-11 43.8 0.0 2.1 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC34424.1 - 2.6e-05 25.0 2.2 7.2e-05 23.5 0.0 2.8 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC34424.1 - 4e-05 23.7 1.1 0.00024 21.2 0.2 2.7 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGC34424.1 - 4.8e-05 23.2 0.0 4.8e-05 23.2 0.0 2.9 3 1 0 3 3 3 1 AAA domain RuvB_N PF05496.7 EGC34424.1 - 0.00011 21.3 0.0 0.00026 20.1 0.0 1.6 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGC34424.1 - 0.00019 21.0 0.0 0.00039 20.1 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain PBP1_TM PF14812.1 EGC34424.1 - 0.00044 20.5 2.3 0.00044 20.5 1.6 3.6 3 0 0 3 3 3 1 Transmembrane domain of transglycosylase PBP1 at N-terminal AAA_28 PF13521.1 EGC34424.1 - 0.00061 19.7 0.1 0.0012 18.7 0.1 1.5 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGC34424.1 - 0.0028 17.3 0.0 0.0077 15.9 0.0 1.8 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGC34424.1 - 0.0059 16.4 0.0 0.019 14.8 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC34424.1 - 0.0088 16.3 5.1 0.0088 16.3 3.5 5.0 4 2 0 4 4 3 1 AAA domain NTPase_1 PF03266.10 EGC34424.1 - 0.016 14.9 1.4 0.1 12.2 0.1 2.4 1 1 1 2 2 2 0 NTPase NACHT PF05729.7 EGC34424.1 - 0.018 14.7 0.1 0.13 11.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain KaiC PF06745.8 EGC34424.1 - 0.019 14.0 0.2 0.079 12.0 0.1 1.9 1 1 0 1 1 1 0 KaiC AAA_16 PF13191.1 EGC34424.1 - 0.02 14.8 0.0 0.085 12.8 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain IstB_IS21 PF01695.12 EGC34424.1 - 0.091 12.1 0.0 0.21 10.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_25 PF13481.1 EGC34424.1 - 0.16 11.3 0.0 0.35 10.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF504 PF04457.7 EGC34425.1 - 0.00028 20.9 0.0 0.00058 19.9 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF504) Ribosomal_S25 PF03297.10 EGC34425.1 - 0.014 15.4 6.0 0.014 15.4 4.2 1.8 2 0 0 2 2 2 0 S25 ribosomal protein Atrophin-1 PF03154.10 EGC34425.1 - 0.55 8.3 16.5 0.83 7.7 11.4 1.2 1 0 0 1 1 1 0 Atrophin-1 family SprA-related PF12118.3 EGC34425.1 - 1.6 8.0 13.7 2.1 7.6 9.5 1.1 1 0 0 1 1 1 0 SprA-related family DUF3812 PF12757.2 EGC34425.1 - 5.5 6.9 20.2 3.2 7.7 11.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3812) Ndc1_Nup PF09531.5 EGC34425.1 - 5.9 5.1 7.9 6.9 4.9 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3987 PF13148.1 EGC34425.1 - 8.3 4.8 15.1 25 3.2 7.5 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) ketoacyl-synt PF00109.21 EGC34426.1 - 9e-61 205.5 0.0 2.1e-60 204.3 0.0 1.7 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34426.1 - 2.6e-46 158.4 0.0 8.6e-31 107.4 0.0 2.3 1 1 1 2 2 2 2 Acyl transferase domain NAD_binding_4 PF07993.7 EGC34426.1 - 1.1e-42 145.7 0.0 2.8e-42 144.3 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC34426.1 - 1.5e-31 108.7 0.0 4.8e-31 107.0 0.0 1.9 2 0 0 2 2 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC34426.1 - 8.9e-25 87.4 0.0 7.5e-23 81.1 0.0 2.4 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC34426.1 - 8.6e-22 77.4 1.2 9.3e-21 74.1 0.0 3.7 4 0 0 4 4 1 1 Methyltransferase domain PS-DH PF14765.1 EGC34426.1 - 1e-20 74.1 0.0 1.6e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC34426.1 - 4.2e-19 69.0 0.0 1.2e-15 57.7 0.0 2.7 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 EGC34426.1 - 5.8e-12 45.5 0.1 5.3e-08 32.5 0.0 2.6 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC34426.1 - 1.2e-07 32.6 0.0 2.7e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC34426.1 - 1.1e-06 28.3 0.1 2.4e-06 27.2 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EGC34426.1 - 1.8e-06 28.0 0.1 0.00016 21.8 0.1 2.7 2 0 0 2 2 2 1 Phosphopantetheine attachment site Methyltransf_11 PF08241.7 EGC34426.1 - 1.9e-05 25.0 0.0 0.00013 22.3 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC34426.1 - 2e-05 24.3 0.0 5.6e-05 22.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34426.1 - 0.00032 21.2 0.0 0.0014 19.1 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC34426.1 - 0.0026 16.7 0.0 0.0058 15.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC34427.1 - 1.1e-62 211.8 0.0 2.6e-62 210.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC34427.1 - 4.4e-44 151.1 0.0 7.3e-44 150.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC34427.1 - 5.7e-32 110.0 0.0 1.9e-31 108.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC34427.1 - 3e-22 79.1 0.0 5.7e-22 78.2 0.0 1.4 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC34427.1 - 4.6e-22 78.5 0.0 7e-22 77.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EGC34427.1 - 2.9e-21 75.8 4.2 2.9e-21 75.7 0.0 3.4 3 0 0 3 3 2 1 Methyltransferase domain adh_short PF00106.20 EGC34427.1 - 1.4e-14 54.3 0.0 2.6e-14 53.5 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC34427.1 - 1.4e-08 35.6 0.0 3.2e-08 34.5 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC34427.1 - 8.1e-07 28.7 0.0 1.8e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC34427.1 - 6.7e-06 26.5 0.0 4.8e-05 23.7 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC34427.1 - 7.6e-06 25.7 0.0 2.2e-05 24.2 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC34427.1 - 0.00013 22.1 0.2 0.00033 20.8 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EGC34427.1 - 0.00018 22.0 0.0 0.00087 19.8 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC34427.1 - 0.018 14.0 0.0 0.039 12.9 0.0 1.5 1 0 0 1 1 1 0 Thiolase, N-terminal domain zf-RING_2 PF13639.1 EGC34428.1 - 6.4e-11 41.8 8.8 1.3e-10 40.9 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC34428.1 - 2.4e-09 36.7 6.2 4.4e-09 35.8 4.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC34428.1 - 3.4e-08 33.3 9.6 7.9e-08 32.2 6.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC34428.1 - 1.1e-07 31.3 9.9 1.1e-07 31.3 6.8 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC34428.1 - 7.8e-05 22.7 6.3 0.00024 21.1 4.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC34428.1 - 8.2e-05 22.2 6.8 8.2e-05 22.2 4.7 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC34428.1 - 0.00054 19.7 8.8 0.0012 18.6 6.1 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC34428.1 - 0.0053 16.3 9.8 0.013 15.1 6.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGC34428.1 - 0.029 13.9 5.3 0.096 12.2 3.7 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGC34428.1 - 0.033 13.9 2.2 0.066 12.9 1.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGC34428.1 - 0.039 13.7 2.1 0.087 12.6 1.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC34428.1 - 0.054 13.2 4.8 0.19 11.4 3.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGC34428.1 - 0.33 10.4 8.6 0.72 9.4 6.0 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_3 PF14369.1 EGC34428.1 - 0.81 9.7 12.3 0.059 13.3 4.6 2.0 2 0 0 2 2 2 0 zinc-finger PRP21_like_P PF12230.3 EGC34429.1 - 4.4e-47 160.5 19.8 4.4e-47 160.5 13.7 2.4 3 0 0 3 3 3 1 Pre-mRNA splicing factor PRP21 like protein Surp PF01805.15 EGC34429.1 - 1.1e-33 114.5 4.8 4.8e-16 58.1 0.2 2.6 2 0 0 2 2 2 2 Surp module ubiquitin PF00240.18 EGC34429.1 - 9.9e-13 47.2 0.2 2.6e-12 45.9 0.1 1.7 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGC34429.1 - 0.035 14.3 1.5 0.058 13.6 0.1 2.2 2 0 0 2 2 2 0 Ubiquitin-like domain alpha-hel2 PF14456.1 EGC34429.1 - 0.055 12.2 1.6 0.091 11.5 1.1 1.3 1 0 0 1 1 1 0 Alpha-helical domain 2 LSM PF01423.17 EGC34430.1 - 2.8e-17 62.0 0.6 3.6e-17 61.6 0.4 1.1 1 0 0 1 1 1 1 LSM domain Flag1_repress PF03614.8 EGC34430.1 - 0.16 11.5 0.1 0.2 11.2 0.0 1.1 1 0 0 1 1 1 0 Repressor of phase-1 flagellin Amidinotransf PF02274.12 EGC34431.1 - 1.9e-64 217.4 0.4 2.3e-64 217.2 0.3 1.1 1 0 0 1 1 1 1 Amidinotransferase DUF1036 PF06282.6 EGC34431.1 - 0.017 15.4 0.7 0.034 14.4 0.0 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1036) RnaseA PF00074.15 EGC34431.1 - 2.4 8.4 9.4 1.5 9.1 2.9 2.9 2 1 1 3 3 3 0 Pancreatic ribonuclease DUF4028 PF13220.1 EGC34431.1 - 4.1 7.1 5.6 0.57 9.8 0.3 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF4028) Acyl_transf_3 PF01757.17 EGC34432.1 - 3.5e-08 32.6 6.2 3.5e-08 32.6 4.3 2.1 2 0 0 2 2 2 1 Acyltransferase family Glyco_transf_28 PF03033.15 EGC34433.1 - 1.7e-11 44.0 0.0 3.4e-11 43.0 0.0 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 28 N-terminal domain Glyco_trans_1_3 PF13528.1 EGC34433.1 - 6.9e-05 22.1 0.0 0.0055 15.9 0.0 2.1 2 0 0 2 2 2 2 Glycosyl transferase family 1 Glyco_tran_28_C PF04101.11 EGC34433.1 - 0.00029 20.5 0.0 0.00081 19.0 0.0 1.7 2 0 0 2 2 2 1 Glycosyltransferase family 28 C-terminal domain UDPGT PF00201.13 EGC34433.1 - 0.00056 18.5 0.0 0.00091 17.8 0.0 1.2 1 0 0 1 1 1 1 UDP-glucoronosyl and UDP-glucosyl transferase EF-hand_6 PF13405.1 EGC34434.1 - 3.7e-05 23.2 2.0 0.0046 16.7 0.3 3.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EGC34434.1 - 4.2e-05 23.5 2.3 4.2e-05 23.5 1.6 3.2 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC34434.1 - 0.0049 16.0 6.8 0.0079 15.4 0.3 3.5 3 0 0 3 3 3 1 EF hand EF-hand_9 PF14658.1 EGC34434.1 - 0.1 12.5 0.2 2.2 8.2 0.1 3.1 3 1 0 3 3 3 0 EF-hand domain EF-hand_5 PF13202.1 EGC34434.1 - 1.1 8.7 7.1 0.12 11.7 0.7 2.6 3 0 0 3 3 3 0 EF hand EF-hand_8 PF13833.1 EGC34434.1 - 5.5 6.6 7.9 0.78 9.4 0.4 3.2 4 0 0 4 4 4 0 EF-hand domain pair MtrB PF05440.7 EGC34435.1 - 7.9 6.5 15.9 16 5.6 0.1 5.8 4 2 3 7 7 7 0 Tetrahydromethanopterin S-methyltransferase subunit B TMEM154 PF15102.1 EGC34436.1 - 0.00042 20.0 0.0 0.00042 20.0 0.0 4.4 3 1 1 5 5 5 1 TMEM154 protein family DUF4448 PF14610.1 EGC34436.1 - 0.0041 16.6 0.0 0.0041 16.6 0.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF4448) DUF3377 PF11857.3 EGC34436.1 - 0.029 13.9 0.0 0.2 11.2 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3377) TFIIF_alpha PF05793.7 EGC34436.1 - 0.12 10.7 25.7 0.009 14.4 14.2 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) DUF912 PF06024.7 EGC34436.1 - 0.74 9.8 0.0 0.74 9.8 0.0 3.5 2 1 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mitofilin PF09731.4 EGC34436.1 - 1.1 7.8 15.2 1.6 7.2 10.6 1.2 1 0 0 1 1 1 0 Mitochondrial inner membrane protein MIP-T3 PF10243.4 EGC34436.1 - 2.3 6.5 28.4 3.6 5.9 19.7 1.2 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 RR_TM4-6 PF06459.7 EGC34436.1 - 6.3 6.6 17.5 11 5.7 12.2 1.4 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 FNIP PF05725.7 EGC34437.1 - 1.3e-137 447.5 93.1 2.1e-14 53.1 0.5 14.6 5 1 11 18 18 18 17 FNIP Repeat UMP1 PF05348.6 EGC34438.1 - 1.6e-20 73.4 0.1 1.8e-20 73.2 0.1 1.1 1 0 0 1 1 1 1 Proteasome maturation factor UMP1 Ceramidase_alk PF04734.8 EGC34439.1 - 1.9e-277 921.6 0.9 2.1e-277 921.4 0.7 1.0 1 0 0 1 1 1 1 Neutral/alkaline non-lysosomal ceramidase ParBc_2 PF08857.6 EGC34440.1 - 9.1e-55 184.9 0.0 1.1e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 Putative ParB-like nuclease MdoG PF04349.7 EGC34440.1 - 0.063 11.5 0.0 0.079 11.2 0.0 1.2 1 0 0 1 1 1 0 Periplasmic glucan biosynthesis protein, MdoG Fe_dep_repress PF01325.14 EGC34440.1 - 0.12 12.3 0.0 15 5.6 0.0 2.3 2 0 0 2 2 2 0 Iron dependent repressor, N-terminal DNA binding domain TPR_17 PF13431.1 EGC34441.1 - 0.025 14.7 11.6 2.4 8.5 0.1 5.3 4 1 2 6 6 6 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34441.1 - 0.38 10.4 4.4 0.48 10.1 0.1 3.2 4 0 0 4 4 4 0 TPR repeat 7tm_3 PF00003.17 EGC34443.1 - 5.2e-41 140.5 14.5 7.4e-41 140.0 10.0 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC34443.1 - 5.8e-19 67.9 0.1 1.3e-18 66.7 0.0 1.6 1 0 0 1 1 1 1 Basic membrane protein Kei1 PF08552.6 EGC34443.1 - 0.067 12.8 0.0 0.067 12.8 0.0 2.4 3 1 0 3 3 3 0 Inositolphosphorylceramide synthase subunit Kei1 UPF0542 PF15086.1 EGC34443.1 - 0.073 12.7 0.0 2.3 8.0 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein family UPF0542 adh_short PF00106.20 EGC34444.1 - 3.2e-15 56.4 0.0 5.2e-15 55.7 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC34444.1 - 3e-05 23.7 0.0 4.1e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 KR domain 7tm_3 PF00003.17 EGC34445.1 - 7.7e-40 136.7 17.1 1.1e-39 136.1 11.9 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC34445.1 - 1.4e-15 56.8 2.0 2.1e-15 56.2 1.4 1.2 1 0 0 1 1 1 1 Basic membrane protein Pox_A9 PF04835.7 EGC34445.1 - 0.11 12.4 1.8 0.37 10.7 1.3 1.9 1 0 0 1 1 1 0 A9 protein conserved region OTU PF02338.14 EGC34446.1 - 8.9e-15 55.3 0.1 1.7e-14 54.4 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Suf PF05843.9 EGC34447.1 - 1.1e-90 304.1 1.6 1.1e-90 304.1 1.1 7.2 5 3 2 7 7 5 2 Suppressor of forked protein (Suf) TPR_14 PF13428.1 EGC34447.1 - 3.4e-10 39.6 0.0 0.0039 17.6 0.0 5.8 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34447.1 - 2.2e-06 28.1 0.2 0.014 16.0 0.0 4.1 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC34447.1 - 4e-06 27.0 0.1 0.0001 22.5 0.0 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC34447.1 - 1.7e-05 24.9 3.3 0.13 12.8 0.0 5.3 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34447.1 - 1.8e-05 24.2 0.1 8e-05 22.2 0.1 2.2 1 0 0 1 1 1 1 TPR repeat TPR_2 PF07719.12 EGC34447.1 - 4.1e-05 23.1 3.7 1.9 8.5 0.0 4.8 5 0 0 5 5 5 2 Tetratricopeptide repeat HAT PF02184.11 EGC34447.1 - 6.8e-05 22.5 0.1 0.12 12.1 0.0 3.0 2 0 0 2 2 2 2 HAT (Half-A-TPR) repeat TPR_8 PF13181.1 EGC34447.1 - 0.021 14.5 0.3 0.55 10.1 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC34447.1 - 0.1 12.5 2.9 1.9 8.4 0.1 3.5 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_17 PF13431.1 EGC34447.1 - 0.28 11.4 0.0 0.28 11.4 0.0 4.9 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC34447.1 - 0.82 9.3 4.4 7.7 6.3 0.1 3.6 4 0 0 4 4 4 0 Tetratricopeptide repeat DivIC PF04977.10 EGC34448.1 - 0.051 13.0 3.7 0.22 10.9 2.5 2.1 1 0 0 1 1 1 0 Septum formation initiator IncA PF04156.9 EGC34448.1 - 0.38 10.3 3.7 0.68 9.4 2.6 1.4 1 0 0 1 1 1 0 IncA protein DUF4342 PF14242.1 EGC34448.1 - 2.2 8.1 5.2 2.3 8.0 0.1 3.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4342) EVI2A PF05399.6 EGC34449.1 - 0.00067 18.9 9.3 0.00086 18.6 6.4 1.1 1 0 0 1 1 1 1 Ectropic viral integration site 2A protein (EVI2A) TMEM154 PF15102.1 EGC34449.1 - 0.034 13.8 3.6 0.19 11.4 2.5 2.1 1 1 0 1 1 1 0 TMEM154 protein family DUF912 PF06024.7 EGC34449.1 - 0.048 13.7 0.2 0.048 13.7 0.1 2.7 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 EGC34449.1 - 0.082 11.9 8.2 0.097 11.6 5.7 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein TMEM171 PF15471.1 EGC34449.1 - 4.5 5.9 11.3 3.2 6.4 6.9 1.5 1 1 0 1 1 1 0 Transmembrane protein family 171 zf-C3HC4_2 PF13923.1 EGC34450.1 - 9.8e-12 44.7 11.5 3.1e-11 43.1 8.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC34450.1 - 2.6e-11 43.1 9.7 5.7e-11 42.0 6.7 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC34450.1 - 8.4e-11 41.3 9.8 1.9e-10 40.2 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC34450.1 - 9.1e-10 38.1 8.2 1.9e-09 37.0 5.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC34450.1 - 4.8e-08 32.5 10.5 1.3e-07 31.1 7.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC34450.1 - 7.2e-07 29.2 8.9 3.2e-06 27.1 6.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC34450.1 - 2e-06 27.4 2.6 2e-06 27.4 1.8 2.3 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGC34450.1 - 2.7e-06 27.0 7.7 5.4e-06 26.1 4.7 1.9 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC34450.1 - 1.3e-05 24.9 8.3 1.3e-05 24.9 5.7 2.2 2 1 0 2 2 2 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC34450.1 - 0.0093 15.4 6.2 0.02 14.4 4.3 1.6 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC34450.1 - 0.017 14.9 7.6 0.47 10.3 5.3 2.4 1 1 1 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-Nse PF11789.3 EGC34450.1 - 0.19 11.2 5.1 0.34 10.4 3.1 1.7 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-P11 PF03854.9 EGC34450.1 - 0.54 9.7 10.4 16 5.0 7.3 2.5 2 1 1 3 3 3 0 P-11 zinc finger zf-RING_4 PF14570.1 EGC34450.1 - 0.72 9.4 14.6 0.66 9.6 5.6 3.0 3 0 0 3 3 3 0 RING/Ubox like zinc-binding domain DZR PF12773.2 EGC34450.1 - 6.2 6.7 9.5 5 7.0 4.8 2.2 2 1 0 2 2 2 0 Double zinc ribbon p450 PF00067.17 EGC34452.1 - 1.6e-54 185.2 0.6 1.8e-54 184.9 0.4 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pantoate_transf PF02548.10 EGC34453.1 - 1.1e-93 313.0 0.9 1.3e-90 303.0 0.0 2.4 1 1 1 2 2 2 2 Ketopantoate hydroxymethyltransferase ApbA_C PF08546.6 EGC34453.1 - 6.3e-34 116.6 0.1 1.4e-33 115.5 0.0 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA C terminal ApbA PF02558.11 EGC34453.1 - 1.4e-28 99.2 0.2 1.4e-28 99.2 0.2 2.0 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_Gly3P_dh_N PF01210.18 EGC34453.1 - 1.8e-05 24.5 0.4 1.8e-05 24.5 0.3 3.6 4 0 0 4 4 4 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus UDPG_MGDP_dh_N PF03721.9 EGC34453.1 - 0.00077 18.8 0.0 0.0022 17.4 0.0 1.8 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 3HCDH_N PF02737.13 EGC34453.1 - 0.041 13.5 0.9 0.23 11.0 0.0 2.5 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain ThiF PF00899.16 EGC34453.1 - 0.092 12.5 2.2 0.75 9.6 0.0 2.8 3 0 0 3 3 3 0 ThiF family CoA_binding_2 PF13380.1 EGC34453.1 - 0.094 12.8 0.1 8.8 6.5 0.0 2.9 2 1 0 2 2 2 0 CoA binding domain DUF2762 PF10960.3 EGC34454.1 - 0.032 13.9 0.2 0.3 10.8 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) Baculo_11_kDa PF06143.6 EGC34454.1 - 1.6 8.1 15.5 2.4 7.5 0.5 4.6 4 0 0 4 4 4 0 Baculovirus 11 kDa family Na_Ca_ex PF01699.19 EGC34455.1 - 1.5e-24 86.2 24.9 1.3e-13 50.7 5.8 2.1 2 0 0 2 2 2 2 Sodium/calcium exchanger protein Pex24p PF06398.6 EGC34455.1 - 0.1 11.3 0.4 9.3 4.9 0.0 2.2 2 0 0 2 2 2 0 Integral peroxisomal membrane peroxin DUF2593 PF10767.4 EGC34455.1 - 0.11 12.1 0.2 0.11 12.1 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2593) Use1 PF09753.4 EGC34456.1 - 2.6e-18 66.3 23.4 2.5e-16 59.8 8.3 3.6 1 1 1 2 2 2 2 Membrane fusion protein Use1 SNARE PF05739.14 EGC34456.1 - 0.0072 15.9 1.4 0.0072 15.9 1.0 2.6 3 0 0 3 3 3 1 SNARE domain 60KD_IMP PF02096.15 EGC34456.1 - 0.2 11.3 9.7 0.77 9.3 0.0 3.0 3 0 0 3 3 3 0 60Kd inner membrane protein UPF0118 PF01594.11 EGC34456.1 - 0.61 9.0 6.0 0.039 12.9 0.3 1.8 2 0 0 2 2 2 0 Domain of unknown function DUF20 Laminin_EGF PF00053.19 EGC34457.1 - 3.8e-05 23.5 20.8 0.005 16.7 2.2 3.0 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC34457.1 - 7.9e-05 22.7 20.7 0.017 15.2 7.9 3.1 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC34457.1 - 0.0028 17.6 8.8 0.0059 16.6 2.0 3.0 2 0 0 2 2 2 1 Human growth factor-like EGF Abhydrolase_5 PF12695.2 EGC34458.1 - 8.9e-22 77.4 0.0 1.6e-21 76.6 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC34458.1 - 1.2e-15 58.0 0.0 8.7e-14 51.9 0.0 2.1 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34458.1 - 5.3e-11 42.5 0.0 2.7e-06 27.1 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold BAAT_C PF08840.6 EGC34458.1 - 1.3e-08 34.7 0.0 0.003 17.2 0.0 2.2 1 1 0 2 2 2 2 BAAT / Acyl-CoA thioester hydrolase C terminal Peptidase_S9 PF00326.16 EGC34458.1 - 7.1e-07 28.6 0.0 6.5e-06 25.5 0.0 2.1 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF818 PF05677.7 EGC34458.1 - 3.8e-06 25.8 0.0 6.4e-06 25.1 0.0 1.3 1 1 0 1 1 1 1 Chlamydia CHLPS protein (DUF818) Abhydrolase_2 PF02230.11 EGC34458.1 - 5.9e-05 22.5 0.0 0.0067 15.8 0.0 2.5 2 1 0 3 3 3 1 Phospholipase/Carboxylesterase DLH PF01738.13 EGC34458.1 - 0.00014 21.2 0.0 0.0014 17.9 0.0 2.0 1 1 0 1 1 1 1 Dienelactone hydrolase family AXE1 PF05448.7 EGC34458.1 - 0.00015 20.4 0.1 0.063 11.7 0.0 3.0 2 1 1 3 3 3 1 Acetyl xylan esterase (AXE1) DUF1057 PF06342.7 EGC34458.1 - 0.0016 17.3 0.0 0.0028 16.5 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF1057) Hydrolase_4 PF12146.3 EGC34458.1 - 0.0079 16.0 0.0 0.045 13.6 0.0 2.1 3 0 0 3 3 3 1 Putative lysophospholipase DUF829 PF05705.9 EGC34458.1 - 0.016 14.8 0.0 0.032 13.9 0.0 1.5 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF829) FSH1 PF03959.8 EGC34458.1 - 0.031 13.7 0.0 0.2 11.0 0.0 2.0 1 1 0 1 1 1 0 Serine hydrolase (FSH1) DUF2305 PF10230.4 EGC34458.1 - 0.057 12.8 0.0 0.18 11.2 0.0 1.7 1 1 1 2 2 2 0 Uncharacterised conserved protein (DUF2305) Lipase_3 PF01764.20 EGC34458.1 - 0.13 11.8 0.0 0.23 11.0 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) RasGEF PF00617.14 EGC34459.1 - 5.1e-58 195.9 0.6 3.2e-57 193.3 0.4 2.5 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC34459.1 - 7.4e-16 58.1 0.7 7.4e-16 58.1 0.5 5.2 4 1 0 4 4 4 1 RasGEF N-terminal motif DEP PF00610.16 EGC34459.1 - 2.7e-08 33.4 0.2 1.6e-07 30.9 0.0 2.2 2 0 0 2 2 2 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) DUF962 PF06127.6 EGC34460.1 - 2e-23 82.0 0.1 4.8e-23 80.8 0.0 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF962 PF06127.6 EGC34461.1 - 3.7e-11 42.7 0.6 9.7e-11 41.4 0.4 1.7 1 1 0 1 1 1 1 Protein of unknown function (DUF962) DUF1240 PF06836.7 EGC34461.1 - 0.38 11.0 4.8 0.56 10.4 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1240) Abhydrolase_6 PF12697.2 EGC34463.1 - 2.5e-11 43.8 0.0 5.3e-11 42.8 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC34463.1 - 4.1e-11 42.8 0.0 6.9e-11 42.0 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34463.1 - 1.4e-09 37.8 0.0 1.8e-08 34.2 0.0 2.1 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF676 PF05057.9 EGC34463.1 - 0.0091 15.3 0.0 0.013 14.7 0.0 1.4 1 0 0 1 1 1 1 Putative serine esterase (DUF676) DUF915 PF06028.6 EGC34463.1 - 0.026 13.6 0.2 0.07 12.2 0.1 1.7 1 0 0 1 1 1 0 Alpha/beta hydrolase of unknown function (DUF915) PARP PF00644.15 EGC34464.1 - 2.4e-17 63.0 4.0 5.7e-14 52.0 0.0 2.7 2 1 1 3 3 3 2 Poly(ADP-ribose) polymerase catalytic domain DUF3715 PF12509.3 EGC34464.1 - 0.0059 16.4 0.0 0.0082 16.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3715) Staphostatin_A PF09022.5 EGC34464.1 - 0.33 10.8 1.8 4.2 7.2 0.0 2.2 2 0 0 2 2 2 0 Staphostatin A EGF_2 PF07974.8 EGC34465.1 - 0.12 12.6 12.4 0.24 11.6 8.6 1.5 1 0 0 1 1 1 0 EGF-like domain MtrF PF09472.5 EGC34466.1 - 0.0011 18.0 1.4 0.0019 17.4 1.0 1.3 1 0 0 1 1 1 1 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Podoplanin PF05808.6 EGC34466.1 - 0.0021 17.6 0.4 0.0025 17.4 0.3 1.1 1 0 0 1 1 1 1 Podoplanin MSC PF09402.5 EGC34466.1 - 0.0091 14.7 0.1 0.01 14.6 0.1 1.0 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Adeno_E3_CR2 PF02439.10 EGC34466.1 - 0.02 14.4 5.1 0.031 13.8 3.5 1.2 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 DAP10 PF07213.6 EGC34466.1 - 0.034 13.9 0.1 0.042 13.6 0.0 1.1 1 0 0 1 1 1 0 DAP10 membrane protein Syndecan PF01034.15 EGC34466.1 - 0.039 13.6 0.2 0.051 13.2 0.2 1.2 1 0 0 1 1 1 0 Syndecan domain DUF912 PF06024.7 EGC34466.1 - 0.052 13.6 0.2 0.063 13.3 0.1 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Mid2 PF04478.7 EGC34466.1 - 0.054 12.9 0.8 0.063 12.6 0.6 1.1 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Glycophorin_A PF01102.13 EGC34466.1 - 0.056 13.2 3.0 0.078 12.7 2.0 1.3 1 1 0 1 1 1 0 Glycophorin A Baculo_E56 PF04639.7 EGC34466.1 - 0.086 11.4 0.2 0.097 11.3 0.2 1.0 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope BatA PF07584.6 EGC34466.1 - 0.11 12.6 0.0 0.15 12.2 0.0 1.2 1 0 0 1 1 1 0 Aerotolerance regulator N-terminal EphA2_TM PF14575.1 EGC34466.1 - 0.32 11.4 1.6 0.27 11.6 0.4 1.5 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain HEAT PF02985.17 EGC34467.1 - 3e-05 23.7 1.4 0.28 11.3 0.1 4.8 4 0 0 4 4 4 2 HEAT repeat HEAT_2 PF13646.1 EGC34467.1 - 0.0072 16.5 0.0 14 6.0 0.0 3.8 3 0 0 3 3 3 2 HEAT repeats Lipocalin_6 PF13944.1 EGC34468.1 - 0.034 14.2 0.4 0.034 14.2 0.3 1.1 1 0 0 1 1 1 0 Lipocalin-like domain DUF2424 PF10340.4 EGC34468.1 - 1.1 7.7 4.9 1.1 7.7 3.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2424) ABC2_membrane PF01061.19 EGC34469.1 - 1.6e-31 109.1 25.8 1.6e-31 109.1 17.9 2.1 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC34469.1 - 6.3e-29 101.0 0.1 1.2e-28 100.1 0.1 1.5 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC34469.1 - 1.7e-06 28.2 0.6 1.7e-06 28.2 0.4 4.2 3 2 0 3 3 3 1 AAA domain AAA_18 PF13238.1 EGC34469.1 - 6.7e-05 23.2 0.1 0.00027 21.2 0.1 2.1 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC34469.1 - 0.00016 22.4 0.1 0.00041 21.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGC34469.1 - 0.00042 19.7 0.1 0.001 18.5 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC34469.1 - 0.00066 19.1 0.0 0.0011 18.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGC34469.1 - 0.0024 17.0 0.4 0.0043 16.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGC34469.1 - 0.0026 17.0 0.6 0.88 8.7 0.0 2.5 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_22 PF13401.1 EGC34469.1 - 0.013 15.6 0.1 0.043 13.9 0.1 2.0 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGC34469.1 - 0.019 14.8 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC34469.1 - 0.038 13.9 0.0 0.061 13.3 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_10 PF12846.2 EGC34469.1 - 0.13 11.6 0.1 0.24 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain PDR_CDR PF06422.7 EGC34469.1 - 0.18 11.4 0.1 0.18 11.4 0.1 3.1 2 1 1 3 3 3 0 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGC34469.1 - 0.52 9.2 40.9 0.0092 15.0 22.9 2.0 2 1 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EGC34470.1 - 2.4e-34 118.3 27.2 5.2e-34 117.2 18.9 1.6 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC34470.1 - 8.2e-27 94.1 0.2 8.2e-27 94.1 0.1 2.6 2 1 0 2 2 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EGC34470.1 - 3.9e-09 35.9 25.5 3.9e-09 35.9 17.6 2.6 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGC34470.1 - 2e-08 34.5 23.3 0.0011 19.0 0.2 3.5 2 1 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EGC34470.1 - 9.9e-06 24.9 0.2 2.5e-05 23.7 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC34470.1 - 0.00035 20.0 0.1 0.00066 19.1 0.1 1.4 1 0 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGC34470.1 - 0.00044 19.4 0.1 0.001 18.3 0.1 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC34470.1 - 0.0014 18.7 0.1 0.0043 17.1 0.1 1.9 1 1 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGC34470.1 - 0.0022 17.2 0.0 0.0022 17.2 0.0 3.1 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGC34470.1 - 0.004 17.9 1.7 0.0056 17.4 0.0 2.1 2 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC34470.1 - 0.0041 17.4 0.1 0.0041 17.4 0.0 3.5 2 1 1 3 3 2 1 AAA domain AAA_16 PF13191.1 EGC34470.1 - 0.0048 16.8 0.0 0.0069 16.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_33 PF13671.1 EGC34470.1 - 0.028 14.3 0.0 0.057 13.2 0.0 1.6 1 0 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGC34470.1 - 0.051 13.4 0.1 0.3 11.0 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EGC34470.1 - 0.24 11.3 0.2 0.42 10.5 0.1 1.4 1 0 0 1 1 1 0 AAA domain ADP_ribosyl_GH PF03747.9 EGC34471.1 - 1.1e-44 153.4 0.0 1.3e-44 153.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylglycohydrolase Methyltransf_23 PF13489.1 EGC34472.1 - 1.7e-16 60.3 0.0 2e-16 60.0 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34472.1 - 8.6e-14 51.3 0.0 1e-13 51.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC34472.1 - 2e-12 47.4 0.0 3e-12 46.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34472.1 - 2.1e-12 47.6 0.0 2.9e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34472.1 - 2e-11 44.2 0.0 2.9e-11 43.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGC34472.1 - 1.7e-07 30.2 0.0 2.5e-07 29.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Methyltransf_25 PF13649.1 EGC34472.1 - 2.7e-07 30.8 0.0 4.8e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGC34472.1 - 2.2e-05 23.7 0.0 3.2e-05 23.2 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) CMAS PF02353.15 EGC34472.1 - 5e-05 22.5 0.0 7.6e-05 21.9 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MTS PF05175.9 EGC34472.1 - 7.3e-05 22.2 0.0 0.00012 21.5 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC34472.1 - 0.00014 21.9 0.0 0.00052 20.0 0.0 1.8 1 1 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGC34472.1 - 0.0009 18.1 0.0 0.0091 14.9 0.0 1.9 1 1 0 2 2 2 1 DREV methyltransferase Ubie_methyltran PF01209.13 EGC34472.1 - 0.0026 16.8 0.0 0.0036 16.4 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family TehB PF03848.9 EGC34472.1 - 0.014 14.5 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB AdoMet_MTase PF07757.8 EGC34472.1 - 0.031 14.3 0.5 0.064 13.3 0.1 1.7 1 1 1 2 2 2 0 Predicted AdoMet-dependent methyltransferase zf-C3HC4_2 PF13923.1 EGC34474.1 - 0.00021 21.2 17.5 0.00021 21.2 12.1 3.9 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC34474.1 - 0.0015 18.1 12.2 0.0015 18.1 8.5 3.5 3 0 0 3 3 3 3 Zinc finger, C3HC4 type (RING finger) CLU PF13236.1 EGC34475.1 - 1.1e-47 162.2 0.0 2.8e-47 160.9 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGC34475.1 - 4.3e-10 39.7 0.5 4.3e-10 39.7 0.4 3.9 3 1 0 3 3 3 1 Translation initiation factor eIF3 subunit 135 RabGAP-TBC PF00566.13 EGC34476.1 - 2.6e-46 157.7 9.7 2.6e-46 157.7 6.7 3.2 3 0 0 3 3 3 1 Rab-GTPase-TBC domain DUF4571 PF15137.1 EGC34476.1 - 0.024 14.0 1.3 0.055 12.8 0.9 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4571) Pyr_redox_2 PF07992.9 EGC34477.1 - 1.4e-18 67.5 0.0 2.7e-18 66.5 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC34477.1 - 4.7e-06 26.9 0.1 0.035 14.5 0.0 2.9 3 0 0 3 3 3 2 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC34477.1 - 0.0094 14.8 0.1 0.017 14.0 0.0 1.5 1 0 0 1 1 1 1 L-lysine 6-monooxygenase (NADPH-requiring) NAD_binding_8 PF13450.1 EGC34477.1 - 0.012 15.6 0.0 0.032 14.2 0.0 1.8 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGC34477.1 - 0.062 12.1 0.0 0.32 9.8 0.0 2.0 2 0 0 2 2 2 0 FAD binding domain DAO PF01266.19 EGC34477.1 - 0.079 11.8 0.0 0.26 10.1 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase NAAA-beta PF15508.1 EGC34478.1 - 0.072 13.4 0.0 0.45 10.8 0.0 2.2 1 1 0 1 1 1 0 beta subunit of N-acylethanolamine-hydrolyzing acid amidase Ras PF00071.17 EGC34480.1 - 2.3e-59 199.4 0.1 2.8e-59 199.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34480.1 - 1.2e-19 70.9 0.0 3.9e-19 69.2 0.0 1.7 1 1 1 2 2 2 1 Miro-like protein Arf PF00025.16 EGC34480.1 - 1e-12 47.6 0.0 1.4e-12 47.1 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC34480.1 - 2.8e-06 27.2 0.1 4.4e-06 26.6 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC34480.1 - 6.4e-05 22.4 0.1 0.0018 17.7 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC34480.1 - 0.00043 19.4 0.0 0.00073 18.7 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC34480.1 - 0.0052 16.0 0.0 0.015 14.5 0.0 1.7 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EGC34480.1 - 0.023 14.2 0.0 0.051 13.1 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGC34480.1 - 0.042 13.9 0.0 0.1 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_15 PF13175.1 EGC34480.1 - 0.09 11.8 0.1 0.11 11.5 0.1 1.1 1 0 0 1 1 1 0 AAA ATPase domain TPR_19 PF14559.1 EGC34481.1 - 1.6e-07 31.5 0.1 2.1e-05 24.7 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34481.1 - 3.3e-07 29.8 0.2 0.021 14.4 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EGC34481.1 - 3.4e-07 29.5 0.2 0.029 14.1 0.0 3.0 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC34481.1 - 1.5e-05 24.5 0.0 0.39 10.7 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34481.1 - 4.8e-05 23.8 0.0 0.0011 19.5 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC34481.1 - 8.3e-05 22.4 0.0 0.00025 20.9 0.0 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC34481.1 - 0.00077 18.9 0.0 1.1 8.9 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC34481.1 - 0.002 17.7 0.0 0.58 10.0 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC34481.1 - 0.0079 16.7 0.0 2.9 8.7 0.0 3.4 2 1 1 3 3 3 1 Tetratricopeptide repeat Clathrin PF00637.15 EGC34481.1 - 0.033 13.7 5.0 0.35 10.4 0.1 3.0 2 1 1 3 3 3 0 Region in Clathrin and VPS Abhydro_lipase PF04083.11 EGC34482.1 - 1.2e-21 75.8 0.1 2.2e-21 74.9 0.0 1.5 1 0 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGC34482.1 - 1.6e-09 37.6 0.0 3.3e-09 36.6 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC34482.1 - 1.5e-07 31.2 0.0 4.3e-07 29.7 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC34482.1 - 0.012 15.4 0.0 0.024 14.5 0.0 1.5 1 1 0 1 1 1 0 Alpha/beta hydrolase family DUF1620 PF07774.8 EGC34483.1 - 6.1e-50 169.4 2.6 6.1e-50 169.4 1.8 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1620) PQQ_2 PF13360.1 EGC34483.1 - 0.00012 21.6 0.1 1.8 7.9 0.0 3.6 3 0 0 3 3 3 2 PQQ-like domain PQQ PF01011.16 EGC34483.1 - 0.037 13.5 0.0 13 5.5 0.0 3.5 4 0 0 4 4 4 0 PQQ enzyme repeat DUF4619 PF15398.1 EGC34484.1 - 0.039 13.3 5.2 0.077 12.4 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4619) RhoGEF PF00621.15 EGC34485.1 - 1.4e-52 178.1 4.0 1.4e-52 178.1 2.7 1.8 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EGC34485.1 - 3.1e-18 65.4 14.0 6.3e-18 64.4 9.7 1.5 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGC34485.1 - 1.4e-12 47.7 1.9 1.4e-12 47.7 1.3 3.2 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EGC34485.1 - 0.023 14.9 0.0 0.13 12.4 0.0 2.4 1 0 0 1 1 1 0 Pleckstrin homology domain HPS3_Mid PF14762.1 EGC34488.1 - 9.5e-33 113.2 4.9 2.1e-32 112.1 3.4 1.6 1 0 0 1 1 1 1 Hermansky-Pudlak syndrome 3, middle region HPS3_N PF14761.1 EGC34488.1 - 2.7e-10 40.0 2.1 3.3e-09 36.4 0.2 2.7 2 1 0 2 2 2 1 Hermansky-Pudlak syndrome 3 TPR_1 PF00515.23 EGC34488.1 - 0.059 12.9 1.2 0.34 10.5 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat Pkinase PF00069.20 EGC34489.1 - 5.7e-46 156.7 0.0 1.3e-45 155.6 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34489.1 - 3e-28 98.5 0.2 6.4e-28 97.5 0.0 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGC34489.1 - 0.0049 16.6 0.0 0.066 12.9 0.0 1.9 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC34489.1 - 0.012 14.6 0.1 0.027 13.5 0.1 1.6 1 1 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family XRCC1_N PF01834.11 EGC34490.1 - 1.4e-21 76.5 0.0 2.9e-21 75.5 0.0 1.5 1 0 0 1 1 1 1 XRCC1 N terminal domain BRCT PF00533.21 EGC34490.1 - 1.4e-19 70.0 0.0 8.2e-12 45.1 0.0 2.9 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC34490.1 - 2.2e-11 43.4 0.0 3.6e-10 39.5 0.0 2.4 2 0 0 2 2 2 1 twin BRCT domain I_LWEQ PF01608.12 EGC34490.1 - 0.58 10.0 6.9 0.34 10.8 3.0 1.9 2 0 0 2 2 2 0 I/LWEQ domain VirDNA-topo-I_N PF09266.5 EGC34491.1 - 0.13 12.1 1.3 0.34 10.8 0.9 1.8 1 0 0 1 1 1 0 Viral DNA topoisomerase I, N-terminal Pkinase_Tyr PF07714.12 EGC34493.1 - 3.8e-57 193.3 0.1 5.7e-55 186.1 0.0 3.1 3 0 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 EGC34493.1 - 2.9e-47 161.0 0.0 1.6e-46 158.5 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain PH PF00169.24 EGC34493.1 - 7.2e-12 45.4 0.5 7.2e-12 45.4 0.3 2.7 3 0 0 3 3 3 1 PH domain PH_11 PF15413.1 EGC34493.1 - 2.3e-05 24.6 0.8 2.3e-05 24.6 0.6 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain Interfer-bind PF09294.5 EGC34493.1 - 0.002 18.1 0.1 0.002 18.1 0.1 4.6 5 0 0 5 5 5 1 Interferon-alpha/beta receptor, fibronectin type III Mucin PF01456.12 EGC34493.1 - 3.6 7.3 21.4 0.11 12.2 5.0 2.4 2 0 0 2 2 2 0 Mucin-like glycoprotein ATP-synt_Eps PF04627.8 EGC34494.1 - 4.4e-17 61.3 0.1 5.5e-17 61.0 0.1 1.1 1 0 0 1 1 1 1 Mitochondrial ATP synthase epsilon chain Misat_Tub_SegII PF10644.4 EGC34494.1 - 0.059 13.4 0.1 0.078 13.0 0.0 1.1 1 0 0 1 1 1 0 Misato Segment II tubulin-like domain Na_Ca_ex PF01699.19 EGC34495.1 - 1.1e-18 67.1 19.0 6.4e-13 48.5 7.0 2.5 2 1 0 2 2 2 2 Sodium/calcium exchanger protein Spc42p PF11544.3 EGC34496.1 - 0.032 14.1 6.6 0.23 11.3 3.1 2.7 2 0 0 2 2 2 0 Spindle pole body component Spc42p CEP19 PF14933.1 EGC34496.1 - 0.061 13.6 5.3 0.3 11.3 2.2 2.3 2 0 0 2 2 2 0 CEP19-like protein DUF2457 PF10446.4 EGC34496.1 - 1.1 7.9 7.1 1.6 7.3 4.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) HSP20 PF00011.16 EGC34497.1 - 1.6e-18 66.4 0.6 1e-14 54.1 0.4 2.2 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EGC34497.1 - 0.061 13.8 1.5 0.55 10.8 0.4 2.4 2 1 0 2 2 2 0 CS domain Tim54 PF11711.3 EGC34497.1 - 0.11 11.1 0.7 0.13 10.8 0.5 1.1 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Mucin PF01456.12 EGC34497.1 - 0.21 11.3 7.4 0.26 11.0 5.1 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Presenilin PF01080.12 EGC34497.1 - 1.8 7.2 4.1 2.1 7.1 2.8 1.1 1 0 0 1 1 1 0 Presenilin Macoilin PF09726.4 EGC34497.1 - 3.8 5.6 8.6 4 5.6 6.0 1.0 1 0 0 1 1 1 0 Transmembrane protein Thioredoxin PF00085.15 EGC34498.1 - 0.0016 18.0 0.0 0.002 17.8 0.0 1.1 1 0 0 1 1 1 1 Thioredoxin Phosphodiest PF01663.17 EGC34499.1 - 4.7e-07 29.4 6.8 0.0056 16.0 0.2 3.3 2 1 1 3 3 3 3 Type I phosphodiesterase / nucleotide pyrophosphatase DUF2910 PF11139.3 EGC34499.1 - 0.0099 15.0 2.0 0.19 10.8 0.1 3.2 3 1 0 3 3 3 1 Protein of unknown function (DUF2910) Not1 PF04054.10 EGC34500.1 - 4.3e-133 443.8 6.4 4.3e-133 443.8 4.4 4.7 5 0 0 5 5 5 1 CCR4-Not complex component, Not1 DUF3819 PF12842.2 EGC34500.1 - 4.4e-51 172.4 0.4 4.4e-51 172.4 0.2 3.3 4 0 0 4 4 4 1 Domain of unknown function (DUF3819) PS_Dcarbxylase PF02666.10 EGC34501.1 - 1.7e-64 216.8 0.1 3.1e-64 215.9 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase DUF1077 PF06417.7 EGC34501.1 - 2.2e-37 127.1 2.9 4.8e-37 126.1 2.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1077) ResB PF05140.9 EGC34501.1 - 0.049 12.1 0.8 0.086 11.3 0.0 1.7 2 0 0 2 2 2 0 ResB-like family AIF_C PF14721.1 EGC34501.1 - 0.29 11.3 3.1 0.47 10.6 1.3 2.0 1 1 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF912 PF06024.7 EGC34501.1 - 0.94 9.5 8.1 1.1 9.3 3.4 2.6 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) MFS_1 PF07690.11 EGC34502.1 - 1.7e-17 63.2 44.8 1.2e-11 43.9 22.7 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF4131 PF13567.1 EGC34502.1 - 0.024 14.0 0.6 0.024 14.0 0.4 4.1 2 2 3 5 5 5 0 Domain of unknown function (DUF4131) Myb_DNA-binding PF00249.26 EGC34503.1 - 3.2e-19 68.7 7.9 2.5e-13 49.8 0.9 3.6 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC34503.1 - 2.1e-17 62.9 10.4 1e-10 41.5 0.0 4.1 1 1 3 4 4 4 3 Myb-like DNA-binding domain Ank_4 PF13637.1 EGC34503.1 - 0.02 15.3 0.0 0.16 12.5 0.0 2.5 2 0 0 2 2 2 0 Ankyrin repeats (many copies) Myb_DNA-bind_4 PF13837.1 EGC34503.1 - 0.55 10.3 24.0 0.16 12.1 2.1 3.4 3 1 1 4 4 4 0 Myb/SANT-like DNA-binding domain Dus PF01207.12 EGC34504.1 - 2.8e-51 174.2 0.4 3.2e-51 174.0 0.3 1.2 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) NMO PF03060.10 EGC34504.1 - 0.0079 15.3 0.0 0.29 10.2 0.0 2.4 1 1 1 2 2 2 1 Nitronate monooxygenase PrmA PF06325.8 EGC34504.1 - 0.039 13.0 0.2 0.039 13.0 0.1 2.6 2 1 1 3 3 3 0 Ribosomal protein L11 methyltransferase (PrmA) DUF4634 PF15465.1 EGC34505.1 - 1.3 9.2 5.3 2.2 8.4 2.7 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) ODR4-like PF14778.1 EGC34506.1 - 2.4e-80 269.9 2.8 3.1e-80 269.5 2.0 1.1 1 0 0 1 1 1 1 Olfactory receptor 4-like Atg14 PF10186.4 EGC34507.1 - 6.8e-33 113.8 14.1 8.2e-33 113.6 9.8 1.0 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 JmjC PF02373.17 EGC34507.1 - 0.15 12.2 5.1 6.8 6.9 0.0 3.7 3 1 0 3 3 3 0 JmjC domain, hydroxylase ESSS PF10183.4 EGC34508.1 - 0.025 14.9 0.0 0.037 14.4 0.0 1.2 1 0 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) NDUF_B8 PF05821.6 EGC34508.1 - 0.053 13.1 0.0 0.066 12.8 0.0 1.3 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase ASHI subunit (CI-ASHI or NDUFB8) DUF3029 PF11230.3 EGC34510.1 - 0.022 12.9 0.1 0.037 12.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3029) PRKCSH_1 PF13015.1 EGC34511.1 - 0.00095 18.6 0.5 0.0017 17.8 0.3 1.5 1 0 0 1 1 1 1 Glucosidase II beta subunit-like protein Translin PF01997.11 EGC34512.1 - 7.1e-56 188.9 4.1 8.9e-56 188.6 2.8 1.1 1 0 0 1 1 1 1 Translin family Packaging_FI PF14000.1 EGC34512.1 - 0.074 13.2 0.2 0.13 12.4 0.1 1.3 1 0 0 1 1 1 0 DNA packaging protein FI F-box-like_2 PF13013.1 EGC34512.1 - 0.1 12.2 1.3 0.18 11.5 0.2 2.0 2 1 1 3 3 3 0 F-box-like domain 7tm_2 PF00002.19 EGC34513.1 - 0.00015 20.8 11.9 0.00026 20.1 8.2 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Fz PF01392.17 EGC34513.1 - 0.00019 21.7 2.4 0.00038 20.8 1.6 1.5 1 0 0 1 1 1 1 Fz domain DPBB_1 PF03330.13 EGC34514.1 - 1.6e-08 34.4 0.6 6.4e-08 32.4 0.4 2.1 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGC34514.1 - 0.017 14.7 0.1 0.047 13.3 0.0 1.7 1 0 0 1 1 1 0 Barwin family SCP2 PF02036.12 EGC34515.1 - 1.3e-49 166.6 2.8 4.1e-25 88.0 0.3 2.1 2 0 0 2 2 2 2 SCP-2 sterol transfer family Alkyl_sulf_C PF14864.1 EGC34515.1 - 4e-13 49.4 0.5 3.2e-06 27.1 0.0 2.2 2 0 0 2 2 2 2 Alkyl sulfatase C-terminal HMA PF00403.21 EGC34515.1 - 0.012 15.7 7.6 5.9 7.1 0.1 4.5 2 2 2 4 4 4 0 Heavy-metal-associated domain PB1 PF00564.19 EGC34516.1 - 0.00097 18.7 0.0 0.0011 18.5 0.0 1.1 1 0 0 1 1 1 1 PB1 domain RA PF00788.18 EGC34516.1 - 0.0068 16.8 0.0 0.0095 16.4 0.0 1.4 1 1 0 1 1 1 1 Ras association (RalGDS/AF-6) domain WAK_assoc PF14380.1 EGC34516.1 - 0.043 14.3 1.3 0.055 13.9 0.9 1.2 1 0 0 1 1 1 0 Wall-associated receptor kinase C-terminal Auxin_inducible PF02519.9 EGC34516.1 - 0.1 12.6 0.0 0.16 12.0 0.0 1.4 1 1 0 1 1 1 0 Auxin responsive protein Hydrolase_6 PF13344.1 EGC34517.1 - 0.025 14.4 0.9 6.9 6.6 0.0 2.8 3 0 0 3 3 3 0 Haloacid dehalogenase-like hydrolase Pkinase PF00069.20 EGC34518.1 - 2e-71 240.2 0.0 3.4e-71 239.4 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34518.1 - 3.7e-46 157.2 0.0 6.8e-46 156.4 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC34518.1 - 5.7e-06 25.4 0.0 1.8e-05 23.8 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC34518.1 - 0.0083 15.8 0.0 0.018 14.7 0.0 1.5 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC34518.1 - 0.15 11.0 0.0 0.31 10.0 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family ERCC4 PF02732.10 EGC34520.1 - 4.4e-20 71.8 0.0 4.4e-20 71.8 0.0 3.2 2 1 0 2 2 2 1 ERCC4 domain AAA PF00004.24 EGC34521.1 - 1.1e-40 138.8 0.1 4.5e-40 136.8 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC34521.1 - 1.4e-06 28.0 0.6 8.8e-06 25.4 0.0 2.5 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC34521.1 - 5.6e-06 26.4 0.0 0.0032 17.4 0.0 2.4 1 1 1 2 2 2 2 AAA ATPase domain AAA_2 PF07724.9 EGC34521.1 - 2.2e-05 24.4 0.0 0.00011 22.1 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGC34521.1 - 0.00012 21.2 0.0 0.0003 19.9 0.0 1.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC34521.1 - 0.00015 21.9 0.3 0.0097 16.0 0.2 2.5 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC34521.1 - 0.001 18.9 0.1 0.0033 17.3 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC34521.1 - 0.0011 19.7 0.2 0.0074 17.0 0.0 2.3 2 2 0 2 2 2 1 AAA domain PhoH PF02562.11 EGC34521.1 - 0.0013 18.0 0.0 0.0084 15.3 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein DUF815 PF05673.8 EGC34521.1 - 0.0021 17.0 0.0 0.0051 15.7 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF815) Mg_chelatase PF01078.16 EGC34521.1 - 0.0029 16.8 0.1 0.012 14.8 0.0 2.0 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_33 PF13671.1 EGC34521.1 - 0.0034 17.2 0.2 0.014 15.2 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC34521.1 - 0.005 16.5 0.5 0.014 15.1 0.1 1.8 2 0 0 2 2 2 1 Part of AAA domain IstB_IS21 PF01695.12 EGC34521.1 - 0.0065 15.8 0.1 0.015 14.7 0.1 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGC34521.1 - 0.0087 15.4 0.9 0.39 10.1 0.1 2.6 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC34521.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin AAA_24 PF13479.1 EGC34521.1 - 0.026 14.1 0.5 0.099 12.2 0.1 2.0 2 0 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGC34521.1 - 0.046 13.8 0.0 0.14 12.3 0.0 1.9 2 0 0 2 2 1 0 RNA helicase Sigma54_activat PF00158.21 EGC34521.1 - 0.051 13.0 0.0 0.33 10.4 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain SVA PF05326.6 EGC34521.1 - 0.069 12.9 0.2 0.12 12.1 0.2 1.3 1 0 0 1 1 1 0 Seminal vesicle autoantigen (SVA) AAA_3 PF07726.6 EGC34521.1 - 0.075 12.6 0.1 0.4 10.3 0.0 2.3 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGC34521.1 - 0.082 12.5 0.2 1.5 8.4 0.1 2.5 1 1 0 1 1 1 0 NACHT domain KaiC PF06745.8 EGC34521.1 - 0.083 12.0 2.0 0.15 11.1 0.0 2.3 3 0 0 3 3 3 0 KaiC AAA_18 PF13238.1 EGC34521.1 - 0.089 13.0 0.7 1.7 8.9 0.0 2.8 2 1 0 2 2 2 0 AAA domain ING PF12998.2 EGC34523.1 - 2.1e-25 89.0 7.9 2.1e-25 89.0 5.5 2.0 2 0 0 2 2 2 1 Inhibitor of growth proteins N-terminal histone-binding PHD PF00628.24 EGC34523.1 - 5.7e-10 38.7 7.9 1e-09 37.9 5.5 1.4 1 0 0 1 1 1 1 PHD-finger zf-RING-like PF08746.6 EGC34523.1 - 0.0075 16.2 2.1 0.014 15.4 1.4 1.4 1 0 0 1 1 1 1 RING-like domain Selenoprotein_S PF06936.6 EGC34523.1 - 0.17 11.4 9.3 0.22 11.0 6.5 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) Prominin PF05478.6 EGC34523.1 - 0.19 9.2 10.3 0.22 9.0 7.1 1.1 1 0 0 1 1 1 0 Prominin zf-HC5HC2H PF13771.1 EGC34523.1 - 0.3 11.2 4.0 0.13 12.4 0.5 2.1 2 0 0 2 2 2 0 PHD-like zinc-binding domain GAGA_bind PF06217.7 EGC34523.1 - 0.63 9.9 8.7 0.78 9.6 6.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family LMBR1 PF04791.11 EGC34523.1 - 1.3 7.5 5.6 1.7 7.1 3.9 1.3 1 0 0 1 1 1 0 LMBR1-like membrane protein DUF1664 PF07889.7 EGC34523.1 - 2.6 7.8 8.2 6.7 6.5 4.7 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) End3 PF12761.2 EGC34523.1 - 2.7 7.6 19.9 0.14 11.7 9.0 1.9 1 1 1 2 2 2 0 Actin cytoskeleton-regulatory complex protein END3 FTCD_C PF04961.7 EGC34523.1 - 3.8 6.8 6.6 6.6 6.0 4.6 1.3 1 0 0 1 1 1 0 Formiminotransferase-cyclodeaminase APC_CDC26 PF10471.4 EGC34523.1 - 6.3 7.6 11.4 1.8 9.3 4.8 2.2 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 DUF1451 PF07295.6 EGC34523.1 - 6.7 6.4 10.7 4.2 7.1 5.1 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1451) UCR_6-4kD PF08997.5 EGC34524.1 - 2.5e-05 23.8 0.1 3.1e-05 23.6 0.1 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex, 6.4kD protein QCR10 PF09796.4 EGC34524.1 - 0.16 11.6 1.3 0.83 9.3 0.9 1.9 1 1 0 1 1 1 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) MRP-L47 PF06984.8 EGC34525.1 - 1.7e-19 69.5 1.4 2.4e-19 68.9 0.2 1.8 2 0 0 2 2 2 1 Mitochondrial 39-S ribosomal protein L47 (MRP-L47) Ribosomal_L29 PF00831.18 EGC34525.1 - 5.7e-07 29.1 0.4 5.7e-07 29.1 0.3 2.9 3 0 0 3 3 3 1 Ribosomal L29 protein FlgM PF04316.8 EGC34525.1 - 0.024 14.5 0.3 4.2 7.3 0.1 2.4 2 0 0 2 2 2 0 Anti-sigma-28 factor, FlgM DUF2682 PF10909.3 EGC34525.1 - 0.036 14.3 0.3 6.4 7.1 0.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2682) bZIP_1 PF00170.16 EGC34525.1 - 3.3 7.7 9.4 7 6.6 0.3 3.4 1 1 2 3 3 3 0 bZIP transcription factor MutL_C PF08676.6 EGC34526.1 - 1.2e-16 60.5 0.0 9.2e-16 57.7 0.0 2.4 3 0 0 3 3 3 1 MutL C terminal dimerisation domain HATPase_c_3 PF13589.1 EGC34526.1 - 6.5e-13 48.5 1.5 6.5e-13 48.5 1.0 3.1 3 0 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC34526.1 - 3.1e-07 30.0 0.1 1.2e-06 28.1 0.1 2.0 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase DNA_mis_repair PF01119.14 EGC34526.1 - 6.7e-07 28.7 0.2 2.4e-06 27.0 0.1 2.1 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HU-DNA_bdg PF14848.1 EGC34527.1 - 0.071 12.8 1.1 0.12 12.0 0.8 1.4 1 0 0 1 1 1 0 DNA-binding domain AMP-binding PF00501.23 EGC34528.1 - 1.6e-75 254.1 0.0 2e-75 253.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34528.1 - 8.7e-12 45.8 0.0 1.9e-11 44.7 0.0 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PNP_UDP_1 PF01048.15 EGC34529.1 - 2e-32 112.0 0.4 2.3e-32 111.8 0.3 1.0 1 0 0 1 1 1 1 Phosphorylase superfamily MAGE PF01454.14 EGC34530.1 - 3e-35 121.3 5.0 6.7e-35 120.1 3.5 1.6 1 0 0 1 1 1 1 MAGE family IGR PF09597.5 EGC34530.1 - 0.038 13.8 0.9 0.11 12.4 0.2 2.1 2 0 0 2 2 2 0 IGR protein motif Spt5_N PF11942.3 EGC34530.1 - 1.1 9.9 25.6 1.9 9.1 6.7 2.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Prothymosin PF03247.9 EGC34530.1 - 1.9 8.6 31.5 3.4 7.8 10.3 2.7 2 0 0 2 2 2 0 Prothymosin/parathymosin family BSP_II PF05432.6 EGC34530.1 - 6.5 5.9 25.0 2.8 7.1 5.1 2.4 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) Pox_I1 PF03289.8 EGC34531.1 - 0.03 13.1 0.8 0.035 12.9 0.4 1.2 1 1 0 1 1 1 0 Poxvirus protein I1 Ribosomal_L6e PF01159.14 EGC34531.1 - 0.17 12.1 1.5 0.21 11.8 1.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L6e DIOX_N PF14226.1 EGC34533.1 - 4.9e-25 88.3 0.0 8.1e-25 87.6 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC34533.1 - 8.4e-17 61.2 0.0 1.5e-16 60.4 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily COX6B PF02297.12 EGC34534.1 - 0.0014 18.5 0.3 0.0014 18.5 0.2 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb APP_N PF02177.11 EGC34534.1 - 0.011 15.5 0.2 0.013 15.3 0.2 1.1 1 0 0 1 1 1 0 Amyloid A4 N-terminal heparin-binding Cytidylate_kin2 PF13189.1 EGC34534.1 - 0.022 14.6 0.2 0.024 14.5 0.1 1.0 1 0 0 1 1 1 0 Cytidylate kinase-like family Peptidase_U35_2 PF14550.1 EGC34534.1 - 0.1 12.2 0.1 0.11 12.1 0.1 1.1 1 0 0 1 1 1 0 Putative phage protease XkdF DUF4460 PF14687.1 EGC34535.1 - 4.1e-30 103.8 1.8 4.1e-30 103.8 1.3 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) DUF4461 PF14688.1 EGC34535.1 - 3.6e-07 29.8 0.8 0.00012 21.6 0.5 2.3 1 1 0 1 1 1 1 Domain of unknown function (DUF4461) FDX-ACB PF03147.9 EGC34535.1 - 0.055 13.6 0.3 0.71 10.0 0.0 2.9 3 0 0 3 3 3 0 Ferredoxin-fold anticodon binding domain OST3_OST6 PF04756.8 EGC34536.1 - 6.2e-31 107.1 3.0 8.9e-31 106.6 2.1 1.2 1 0 0 1 1 1 1 OST3 / OST6 family PIN_2 PF10130.4 EGC34537.1 - 0.84 9.6 19.0 3.4 7.7 1.6 3.3 1 1 2 3 3 3 0 PIN domain DUF4259 PF14078.1 EGC34537.1 - 4.6 7.7 8.9 26 5.3 3.6 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4259) zf-CCCH PF00642.19 EGC34538.1 - 4.3e-06 26.2 15.3 0.0005 19.6 0.1 3.2 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) RBB1NT PF08169.6 EGC34538.1 - 0.027 14.4 0.1 0.071 13.0 0.0 1.7 1 0 0 1 1 1 0 RBB1NT (NUC162) domain Defensin_beta PF00711.14 EGC34538.1 - 2 8.4 8.1 0.79 9.7 0.4 2.5 2 0 0 2 2 2 0 Beta defensin E1-E2_ATPase PF00122.15 EGC34539.1 - 3.6e-26 91.6 0.2 8.7e-26 90.3 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGC34539.1 - 1.5e-24 87.1 0.0 3.3e-24 86.1 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EGC34539.1 - 1.8e-22 79.4 0.1 1.8e-22 79.4 0.1 2.5 2 0 0 2 2 2 1 P5-type ATPase cation transporter Hydrolase PF00702.21 EGC34539.1 - 1.8e-16 61.1 0.0 8.4e-16 59.0 0.0 2.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC34539.1 - 0.001 18.4 0.0 0.0025 17.2 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGC34539.1 - 0.0022 17.9 0.0 0.0054 16.6 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HSP20 PF00011.16 EGC34540.1 - 4.3e-12 45.7 1.8 7.2e-12 45.0 1.2 1.4 1 0 0 1 1 1 1 Hsp20/alpha crystallin family DUF1674 PF07896.7 EGC34541.1 - 2.2e-18 66.1 3.4 3.1e-18 65.7 2.4 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1674) KIAA1430 PF13879.1 EGC34541.1 - 0.0032 17.8 2.2 0.004 17.5 1.5 1.1 1 0 0 1 1 1 1 KIAA1430 homologue PH PF00169.24 EGC34542.1 - 9.9e-16 57.8 0.2 9.9e-16 57.8 0.1 4.5 4 1 0 4 4 4 1 PH domain PH_8 PF15409.1 EGC34542.1 - 2.8e-05 24.0 1.7 0.0004 20.3 0.0 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain PH_11 PF15413.1 EGC34542.1 - 0.011 15.9 3.3 0.011 15.9 2.3 4.2 3 2 0 3 3 3 0 Pleckstrin homology domain Myb_CC_LHEQLE PF14379.1 EGC34542.1 - 0.43 10.2 6.2 0.23 11.0 2.1 2.1 2 0 0 2 2 2 0 MYB-CC type transfactor, LHEQLE motif Glyco_hydro_38 PF01074.17 EGC34543.1 - 2.4e-71 240.2 0.4 3.7e-71 239.6 0.3 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGC34543.1 - 1.4e-26 93.3 4.4 1.9e-26 92.9 3.1 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGC34543.1 - 9.1e-15 54.6 0.0 1.9e-14 53.5 0.0 1.6 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Sugar_tr PF00083.19 EGC34544.1 - 1.1e-107 360.3 26.9 1.4e-107 360.1 18.6 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGC34544.1 - 1.4e-39 135.8 29.7 9.1e-26 90.3 5.1 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Myb_DNA-binding PF00249.26 EGC34545.1 - 3.4e-08 33.3 0.2 7.2e-08 32.3 0.2 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC34545.1 - 6e-07 29.4 3.7 1.3e-06 28.3 0.4 2.6 2 0 0 2 2 2 1 Myb-like DNA-binding domain DUF948 PF06103.6 EGC34545.1 - 0.02 14.7 0.7 0.055 13.3 0.5 1.7 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) DUF3984 PF13136.1 EGC34545.1 - 0.057 12.6 4.1 0.11 11.7 2.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3984) FRG2 PF15315.1 EGC34545.1 - 0.61 10.0 3.9 0.3 11.0 0.9 1.8 2 0 0 2 2 2 0 Facioscapulohumeral muscular dystrophy candidate 2 Syntaxin_2 PF14523.1 EGC34546.1 - 9.8e-12 44.8 7.3 9.8e-12 44.8 5.1 2.4 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGC34546.1 - 1.4e-08 34.3 2.9 1.4e-08 34.3 2.0 2.3 3 0 0 3 3 3 1 SNARE domain BOP1NT PF08145.7 EGC34546.1 - 0.0042 16.8 1.6 0.0042 16.8 1.1 2.0 2 0 0 2 2 2 1 BOP1NT (NUC169) domain MCPsignal PF00015.16 EGC34546.1 - 0.71 9.3 5.6 0.086 12.3 1.1 1.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain FHA PF00498.21 EGC34547.1 - 8.8e-12 44.9 0.5 1.8e-11 43.9 0.3 1.6 1 0 0 1 1 1 1 FHA domain CBM49 PF09478.5 EGC34548.1 - 5.3e-15 55.2 0.6 7.3e-15 54.8 0.4 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC34548.1 - 0.36 10.8 4.0 0.23 11.4 0.4 2.2 2 0 0 2 2 2 0 DIM protein CBM49 PF09478.5 EGC34549.1 - 9.6e-15 54.4 0.4 1.3e-14 54.0 0.3 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DIM PF08194.7 EGC34549.1 - 0.095 12.6 0.6 0.24 11.4 0.4 1.7 1 0 0 1 1 1 0 DIM protein DUF663 PF04950.7 EGC34550.1 - 3.1e-87 292.2 0.1 3.1e-87 292.2 0.1 3.4 4 1 1 5 5 5 1 Protein of unknown function (DUF663) AARP2CN PF08142.7 EGC34550.1 - 1.7e-23 81.9 0.1 5.5e-23 80.3 0.1 2.0 1 0 0 1 1 1 1 AARP2CN (NUC121) domain Dynamin_N PF00350.18 EGC34550.1 - 0.044 13.6 0.1 0.044 13.6 0.0 3.4 3 1 0 3 3 3 0 Dynamin family Daxx PF03344.10 EGC34550.1 - 4.3 5.6 31.7 8.5 4.7 22.0 1.5 1 0 0 1 1 1 0 Daxx Family Pkinase_Tyr PF07714.12 EGC34551.1 - 5.3e-68 228.9 0.0 6.8e-68 228.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC34551.1 - 1.4e-56 191.5 0.0 1.9e-56 191.1 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EGC34551.1 - 4.1e-13 48.9 0.0 8.1e-13 47.9 0.0 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 EGC34551.1 - 7e-05 22.6 0.5 0.00026 20.8 0.0 1.9 2 0 0 2 2 2 1 Phosphotransferase enzyme family Kinase-like PF14531.1 EGC34551.1 - 0.0037 16.2 0.0 0.006 15.5 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Cbl_N2 PF02761.9 EGC34551.1 - 0.042 13.9 0.1 0.11 12.5 0.1 1.7 1 0 0 1 1 1 0 CBL proto-oncogene N-terminus, EF hand-like domain ABC1 PF03109.11 EGC34551.1 - 0.091 12.7 0.0 1.4 8.8 0.0 2.5 2 0 0 2 2 2 0 ABC1 family Ribosomal_L37ae PF01780.14 EGC34552.1 - 0.0073 16.1 3.8 0.8 9.6 0.3 2.7 2 0 0 2 2 2 2 Ribosomal L37ae protein family Sigma70_ner PF04546.8 EGC34552.1 - 0.62 9.6 11.9 1.4 8.4 8.2 1.5 1 0 0 1 1 1 0 Sigma-70, non-essential region OrfB_Zn_ribbon PF07282.6 EGC34552.1 - 0.86 9.3 9.3 7.1 6.3 1.4 3.3 3 0 0 3 3 3 0 Putative transposase DNA-binding domain CNH PF00780.17 EGC34554.1 - 1.8e-26 93.1 0.0 3.3e-26 92.3 0.0 1.3 1 0 0 1 1 1 1 CNH domain Vps39_2 PF10367.4 EGC34554.1 - 2.6e-25 88.6 0.0 7e-25 87.3 0.0 1.8 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 Vps39_1 PF10366.4 EGC34554.1 - 5.7e-22 77.7 2.5 5.7e-22 77.7 1.7 2.9 3 1 1 4 4 4 1 Vacuolar sorting protein 39 domain 1 Clathrin PF00637.15 EGC34554.1 - 4.6e-14 52.2 13.8 1.5e-08 34.3 0.3 4.3 3 1 0 4 4 4 2 Region in Clathrin and VPS Flagellin_C PF00700.16 EGC34554.1 - 0.15 12.2 0.4 0.49 10.5 0.0 2.1 2 0 0 2 2 2 0 Bacterial flagellin C-terminal helical region TPR_12 PF13424.1 EGC34554.1 - 0.4 10.6 3.0 18 5.3 0.5 3.2 2 1 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC34554.1 - 1.3 8.7 4.9 5.8 6.6 0.8 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat GP41 PF00517.12 EGC34555.1 - 2.2e-05 24.1 0.3 2.4e-05 23.9 0.2 1.0 1 0 0 1 1 1 1 Retroviral envelope protein DUF2360 PF10152.4 EGC34555.1 - 0.00013 22.2 0.6 0.00015 22.0 0.4 1.1 1 0 0 1 1 1 1 Predicted coiled-coil domain-containing protein (DUF2360) Allexi_40kDa PF05549.6 EGC34555.1 - 0.00042 19.6 0.2 0.00046 19.5 0.1 1.0 1 0 0 1 1 1 1 Allexivirus 40kDa protein Phasin PF05597.6 EGC34555.1 - 0.0034 17.1 0.2 0.0041 16.8 0.2 1.2 1 0 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) NPV_P10 PF05531.7 EGC34555.1 - 0.0062 16.7 0.5 0.097 12.9 0.0 2.1 1 1 1 2 2 2 1 Nucleopolyhedrovirus P10 protein LXG PF04740.7 EGC34555.1 - 0.013 15.2 1.5 0.015 15.1 1.0 1.1 1 0 0 1 1 1 0 LXG domain of WXG superfamily MbeD_MobD PF04899.7 EGC34555.1 - 0.02 14.8 0.4 0.044 13.6 0.3 1.7 1 1 0 1 1 1 0 MbeD/MobD like DUF3452 PF11934.3 EGC34555.1 - 0.026 13.8 0.4 0.026 13.8 0.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3452) Dict-STAT-coil PF09267.5 EGC34555.1 - 0.044 14.0 1.0 0.047 13.9 0.7 1.1 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil HR1 PF02185.11 EGC34555.1 - 0.12 12.1 0.9 0.16 11.7 0.6 1.5 1 1 0 1 1 1 0 Hr1 repeat MIS13 PF08202.6 EGC34555.1 - 0.12 11.4 2.4 0.13 11.3 1.7 1.1 1 0 0 1 1 1 0 Mis12-Mtw1 protein family TraH PF06122.6 EGC34555.1 - 0.12 11.1 0.1 0.12 11.1 0.1 1.0 1 0 0 1 1 1 0 Conjugative relaxosome accessory transposon protein SPX PF03105.14 EGC34555.1 - 0.39 10.4 2.7 0.38 10.5 1.8 1.0 1 0 0 1 1 1 0 SPX domain TGS PF02824.16 EGC34556.1 - 1.8e-19 69.2 0.1 3e-19 68.5 0.0 1.4 1 0 0 1 1 1 1 TGS domain MMR_HSR1 PF01926.18 EGC34556.1 - 9.4e-19 67.4 0.0 1.6e-18 66.7 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC34556.1 - 2.9e-09 36.3 0.0 5.2e-09 35.5 0.0 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B Dynamin_N PF00350.18 EGC34556.1 - 2.7e-05 24.0 0.1 0.016 15.0 0.0 2.4 1 1 1 2 2 2 2 Dynamin family AAA_18 PF13238.1 EGC34556.1 - 0.0051 17.1 0.0 0.013 15.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain Miro PF08477.8 EGC34556.1 - 0.0088 16.5 0.0 0.03 14.8 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein AAA_28 PF13521.1 EGC34556.1 - 0.035 14.0 0.4 0.081 12.8 0.1 1.8 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGC34556.1 - 0.053 12.2 0.5 0.23 10.1 0.1 2.2 2 1 1 3 3 3 0 ArgK protein AIG1 PF04548.11 EGC34556.1 - 0.065 12.3 0.0 0.11 11.6 0.0 1.4 1 0 0 1 1 1 0 AIG1 family KTI12 PF08433.5 EGC34556.1 - 0.084 12.0 0.5 4.5 6.3 0.0 2.6 3 0 0 3 3 3 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGC34556.1 - 0.37 11.6 2.2 0.47 11.2 0.2 2.2 2 2 0 2 2 2 0 AAA domain DUF4188 PF13826.1 EGC34557.1 - 4.8e-05 23.4 0.1 5.8e-05 23.1 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4188) ABM PF03992.11 EGC34557.1 - 0.00029 20.7 0.0 0.00042 20.2 0.0 1.2 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase Glyco_hydro_81 PF03639.8 EGC34557.1 - 0.023 12.7 0.4 0.025 12.6 0.3 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 81 Imm14 PF15428.1 EGC34557.1 - 0.059 13.7 3.3 0.12 12.7 2.3 1.5 1 1 0 1 1 1 0 Immunity protein 14 DUF3291 PF11695.3 EGC34557.1 - 0.11 11.9 0.4 0.16 11.4 0.3 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3291) Peptidase_C1 PF00112.18 EGC34558.1 - 1.1e-76 257.6 1.3 1.5e-76 257.0 0.9 1.2 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC34558.1 - 1.3e-12 47.7 5.8 2.2e-12 47.0 4.1 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC34558.1 - 0.0018 16.8 0.7 0.004 15.7 0.1 1.7 2 0 0 2 2 2 1 Peptidase C1-like family VHP PF02209.14 EGC34559.1 - 9.3e-13 47.6 1.2 4.7e-12 45.3 0.8 2.4 1 0 0 1 1 1 1 Villin headpiece domain PQ-loop PF04193.9 EGC34560.1 - 1.3e-33 114.3 17.1 5.3e-18 64.3 1.9 3.6 3 1 1 4 4 4 2 PQ loop repeat Zip PF02535.17 EGC34560.1 - 0.083 11.8 0.0 0.15 11.0 0.0 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter Ureide_permease PF07168.6 EGC34560.1 - 1 7.9 7.8 0.033 12.8 0.4 2.0 2 1 0 2 2 2 0 Ureide permease PQ-loop PF04193.9 EGC34561.1 - 3.9e-34 115.9 11.3 2.6e-18 65.3 2.8 3.9 3 1 1 4 4 4 2 PQ loop repeat CENP-K PF11802.3 EGC34562.1 - 0.0019 17.5 11.7 0.0019 17.5 8.1 2.6 1 1 1 2 2 2 2 Centromere-associated protein K DUF3439 PF11921.3 EGC34562.1 - 0.024 14.4 5.3 0.048 13.4 3.7 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGC34562.1 - 0.062 11.2 6.3 0.081 10.8 4.4 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Herpes_UL92 PF03048.9 EGC34562.1 - 1.3 8.5 6.2 0.39 10.2 0.3 2.5 2 1 0 2 2 2 0 UL92 family DUF4239 PF14023.1 EGC34562.1 - 7.7 5.8 10.6 1 8.6 0.9 2.8 1 1 1 3 3 3 0 Protein of unknown function (DUF4239) Mucin PF01456.12 EGC34562.1 - 8 6.2 16.3 14 5.4 11.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Secretin_N_2 PF07655.8 EGC34563.1 - 1.4 9.3 24.0 2.3 8.6 16.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC34563.1 - 2.6 8.1 10.4 5.4 7.1 7.2 1.6 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Menin PF05053.8 EGC34563.1 - 3.5 5.7 8.6 4.3 5.3 6.0 1.1 1 0 0 1 1 1 0 Menin Conotoxin PF02950.12 EGC34563.1 - 8.4 7.2 7.2 14 6.5 5.0 1.4 1 0 0 1 1 1 0 Conotoxin Ras PF00071.17 EGC34564.1 - 1e-56 190.7 0.0 1.2e-56 190.5 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34564.1 - 1.8e-17 63.9 0.0 3.3e-17 63.0 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC34564.1 - 5.7e-05 22.4 0.0 8.1e-05 21.9 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family Rep_fac_C PF08542.6 EGC34565.1 - 3.5e-21 74.9 0.4 3.3e-20 71.8 0.0 2.6 3 0 0 3 3 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGC34565.1 - 8.3e-14 51.5 0.1 1.5e-13 50.7 0.0 1.4 1 0 0 1 1 1 1 DNA polymerase III, delta subunit Rad17 PF03215.10 EGC34565.1 - 1.4e-06 27.3 0.5 3.2e-05 22.8 0.0 2.1 1 1 0 2 2 2 1 Rad17 cell cycle checkpoint protein DNA_pol3_delta PF06144.8 EGC34565.1 - 3e-05 23.6 0.1 7.1e-05 22.3 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA PF00004.24 EGC34565.1 - 0.00011 22.4 0.1 0.00033 20.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) TIP49 PF06068.8 EGC34565.1 - 0.00044 19.0 0.0 0.09 11.4 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus AAA_16 PF13191.1 EGC34565.1 - 0.0013 18.7 0.0 0.0081 16.1 0.0 2.3 2 1 0 2 2 2 1 AAA ATPase domain RuvB_N PF05496.7 EGC34565.1 - 0.0017 17.4 0.0 1.4 7.9 0.0 2.9 2 1 1 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC34565.1 - 0.0075 16.4 0.0 0.033 14.3 0.0 2.0 2 1 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EGC34565.1 - 0.017 14.7 0.1 0.82 9.2 0.0 2.3 2 0 0 2 2 2 0 Bacterial dnaA protein ABC_tran PF00005.22 EGC34565.1 - 0.019 15.2 0.0 0.043 14.1 0.0 1.7 1 1 0 1 1 1 0 ABC transporter AAA_11 PF13086.1 EGC34565.1 - 0.019 14.5 0.0 0.035 13.6 0.0 1.4 1 1 0 1 1 1 0 AAA domain Sigma54_activ_2 PF14532.1 EGC34565.1 - 0.027 14.5 0.0 0.16 11.9 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain DUF815 PF05673.8 EGC34565.1 - 0.042 12.7 0.0 0.087 11.7 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Arch_ATPase PF01637.13 EGC34565.1 - 0.055 13.1 0.1 0.097 12.3 0.0 1.6 1 1 0 1 1 1 0 Archaeal ATPase AAA_10 PF12846.2 EGC34565.1 - 0.14 11.5 0.0 0.26 10.7 0.0 1.5 1 1 0 1 1 1 0 AAA-like domain AAA_5 PF07728.9 EGC34565.1 - 0.17 11.5 0.1 0.86 9.3 0.1 2.0 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) Ribosomal_S21e PF01249.13 EGC34566.1 - 8.4e-35 118.5 0.0 8.8e-35 118.5 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein S21e Mre11_DNA_bind PF04152.9 EGC34567.1 - 4.9e-47 160.0 0.2 7.7e-47 159.3 0.1 1.3 1 0 0 1 1 1 1 Mre11 DNA-binding presumed domain Metallophos PF00149.23 EGC34567.1 - 4.1e-27 94.8 3.9 6.3e-27 94.2 2.7 1.3 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC34567.1 - 8.7e-08 32.1 0.3 5e-07 29.6 0.0 2.4 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain EMP24_GP25L PF01105.19 EGC34568.1 - 8.5e-52 175.5 0.7 1e-51 175.2 0.5 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD FlgD_ig PF13860.1 EGC34568.1 - 0.0014 18.3 0.0 0.39 10.4 0.0 2.8 3 0 0 3 3 3 2 FlgD Ig-like domain Gemini_mov PF01708.11 EGC34568.1 - 0.1 12.1 0.1 0.2 11.1 0.1 1.5 1 0 0 1 1 1 0 Geminivirus putative movement protein PHD PF00628.24 EGC34569.1 - 3e-17 62.0 27.6 5e-10 38.9 7.9 2.6 2 0 0 2 2 2 2 PHD-finger PHD_2 PF13831.1 EGC34569.1 - 0.0008 18.6 14.6 0.0022 17.2 4.0 2.5 2 0 0 2 2 2 2 PHD-finger zf-CW PF07496.10 EGC34569.1 - 0.45 10.2 25.2 0.23 11.1 6.1 3.1 2 1 1 3 3 3 0 CW-type Zinc Finger Elf1 PF05129.8 EGC34569.1 - 9.2 6.0 25.0 0.2 11.3 6.4 4.0 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like HCO3_cotransp PF00955.16 EGC34570.1 - 1.2e-81 274.9 22.1 1.1e-46 159.5 5.0 2.4 1 1 1 2 2 2 2 HCO3- transporter family Suc_Fer-like PF06999.7 EGC34571.1 - 9.7e-43 146.8 0.1 1.8e-42 145.9 0.0 1.4 2 0 0 2 2 2 1 Sucrase/ferredoxin-like Guanylate_cyc_2 PF09778.4 EGC34571.1 - 0.0014 17.8 0.0 0.62 9.2 0.0 2.1 2 0 0 2 2 2 2 Guanylylate cyclase Mucin PF01456.12 EGC34571.1 - 0.0029 17.3 9.4 0.0048 16.6 6.5 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein Fer2_2 PF01799.15 EGC34571.1 - 0.024 14.5 0.0 10 6.1 0.0 2.7 3 0 0 3 3 3 0 [2Fe-2S] binding domain SSP160 PF06933.6 EGC34571.1 - 0.049 11.6 9.3 0.063 11.2 6.5 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 YyzF PF14116.1 EGC34571.1 - 0.22 11.5 1.7 5.2 7.0 0.1 2.7 2 0 0 2 2 2 0 YyzF-like protein zf-BED PF02892.10 EGC34571.1 - 0.75 9.6 2.9 6.4 6.6 0.1 2.6 2 0 0 2 2 2 0 BED zinc finger DUF3439 PF11921.3 EGC34571.1 - 1.2 8.8 9.2 2.7 7.7 5.9 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) IF4E PF01652.13 EGC34572.1 - 1.7e-38 131.7 1.3 1.7e-38 131.7 0.9 2.8 3 0 0 3 3 3 1 Eukaryotic initiation factor 4E HI0933_like PF03486.9 EGC34572.1 - 9.3 4.5 15.2 0.11 10.8 2.9 3.0 3 0 0 3 3 3 0 HI0933-like protein SSP160 PF06933.6 EGC34573.1 - 0.023 12.7 3.0 0.028 12.4 2.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF1183 PF06682.7 EGC34573.1 - 0.025 14.1 0.2 0.034 13.7 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) Ded_cyto PF06920.8 EGC34574.1 - 5.5e-48 162.6 2.9 1.4e-47 161.2 0.5 2.6 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC34574.1 - 1.7e-17 63.6 8.0 1.7e-17 63.6 5.6 2.6 3 0 0 3 3 3 1 C2 domain in Dock180 and Zizimin proteins C2 PF00168.25 EGC34574.1 - 0.017 14.9 0.1 0.083 12.7 0.0 2.3 2 0 0 2 2 2 0 C2 domain Sec16_C PF12931.2 EGC34575.1 - 9.1e-37 127.3 0.2 1.8e-36 126.3 0.1 1.4 1 0 0 1 1 1 1 Sec23-binding domain of Sec16 Sec16 PF12932.2 EGC34575.1 - 2.1e-18 66.4 0.2 3.7e-17 62.3 0.0 3.5 2 0 0 2 2 2 1 Vesicle coat trafficking protein Sec16 mid-region MAP7 PF05672.6 EGC34575.1 - 0.66 9.3 33.3 1.4 8.2 23.1 1.4 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DNA_topoisoIV PF00521.15 EGC34576.1 - 2.1e-109 366.2 10.5 4.1e-108 361.9 7.3 2.2 1 1 0 1 1 1 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGC34576.1 - 2.7e-31 108.0 0.4 2.7e-31 108.0 0.3 2.3 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EGC34576.1 - 2.1e-11 43.6 0.3 9.9e-11 41.5 0.0 2.3 2 0 0 2 2 2 1 Toprim domain HATPase_c PF02518.21 EGC34576.1 - 1.4e-07 31.1 0.1 4.7e-07 29.5 0.0 1.9 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Dicty_CTDC PF00526.13 EGC34577.1 - 2.2e-273 879.7 675.4 4.8e-12 45.4 9.6 33.4 34 0 0 34 34 34 32 Dictyostelium (slime mold) repeat Phage_int_SAM_5 PF13102.1 EGC34578.1 - 1.4 8.9 10.3 0.13 12.2 1.1 2.9 3 0 0 3 3 3 0 Phage integrase SAM-like domain ATP_bind_3 PF01171.15 EGC34579.1 - 1.9e-33 115.5 0.0 4.7e-33 114.2 0.0 1.6 1 0 0 1 1 1 1 PP-loop family NAD_synthase PF02540.12 EGC34579.1 - 0.0085 15.0 0.1 0.024 13.5 0.0 1.8 1 1 0 1 1 1 1 NAD synthase SPRY PF00622.23 EGC34579.1 - 0.11 12.5 0.0 0.23 11.5 0.0 1.5 1 0 0 1 1 1 0 SPRY domain Cation_ATPase_C PF00689.16 EGC34580.1 - 0.024 14.1 5.7 0.053 13.0 2.8 2.0 2 0 0 2 2 2 0 Cation transporting ATPase, C-terminus Paramyxo_P PF01806.12 EGC34580.1 - 0.027 13.7 5.2 0.52 9.5 1.1 2.1 2 0 0 2 2 2 0 Paramyxovirinae P phosphoprotein C-terminal region DUF1090 PF06476.7 EGC34580.1 - 0.037 13.6 3.5 0.13 11.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1090) SUR7 PF06687.7 EGC34580.1 - 0.043 13.3 3.4 0.08 12.5 2.3 1.4 1 0 0 1 1 1 0 SUR7/PalI family FlaC_arch PF05377.6 EGC34580.1 - 0.19 11.6 0.2 0.19 11.6 0.2 2.5 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) Doppel PF11466.3 EGC34580.1 - 0.31 10.6 0.2 0.31 10.6 0.1 1.7 2 0 0 2 2 2 0 Prion-like protein Doppel DUF2207 PF09972.4 EGC34580.1 - 5.7 5.3 14.0 0.043 12.4 0.9 2.3 1 1 2 3 3 3 0 Predicted membrane protein (DUF2207) Mitofilin PF09731.4 EGC34581.1 - 7e-44 150.4 49.7 7e-44 150.4 34.5 2.2 1 1 1 2 2 2 1 Mitochondrial inner membrane protein zf-DHHC PF01529.15 EGC34581.1 - 0.54 9.6 7.2 2.1 7.6 0.5 2.8 2 0 0 2 2 2 0 DHHC palmitoyltransferase AD PF09793.4 EGC34582.1 - 6.9e-27 93.1 0.1 9.8e-27 92.6 0.1 1.2 1 0 0 1 1 1 1 Anticodon-binding domain Gemin6 PF06372.7 EGC34582.1 - 0.00052 19.3 0.2 0.068 12.4 0.0 2.3 2 0 0 2 2 2 2 Gemin6 protein adh_short PF00106.20 EGC34583.1 - 2.6e-20 72.9 0.0 3.3e-20 72.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC34583.1 - 1e-06 28.5 0.0 1.4e-06 28.0 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGC34583.1 - 0.001 18.0 0.0 0.0014 17.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGC34583.1 - 0.01 15.3 0.0 0.048 13.0 0.0 1.9 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family DUF2306 PF10067.4 EGC34583.1 - 0.082 13.0 0.1 0.15 12.1 0.1 1.4 1 0 0 1 1 1 0 Predicted membrane protein (DUF2306) Arf PF00025.16 EGC34585.1 - 3.5e-64 215.2 0.1 4.1e-64 215.0 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC34585.1 - 1.6e-13 50.3 0.0 1.7e-13 50.2 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC34585.1 - 4.8e-11 42.1 0.0 5.7e-11 41.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC34585.1 - 2.9e-10 40.6 0.0 3.9e-10 40.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EGC34585.1 - 2.9e-09 36.1 2.0 9.8e-07 27.7 0.1 2.2 1 1 1 2 2 2 2 G-protein alpha subunit Gtr1_RagA PF04670.7 EGC34585.1 - 2.9e-08 33.1 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC34585.1 - 1.1e-05 25.3 0.0 1.5e-05 24.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGC34585.1 - 0.012 15.9 0.1 0.019 15.2 0.0 1.4 1 1 0 1 1 1 0 ABC transporter PduV-EutP PF10662.4 EGC34585.1 - 0.061 12.8 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation SRP54 PF00448.17 EGC34585.1 - 0.09 12.2 0.0 0.17 11.2 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_33 PF13671.1 EGC34585.1 - 0.13 12.1 0.0 0.18 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF825 PF05695.7 EGC34588.1 - 0.0095 13.3 0.4 0.011 13.2 0.3 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF825) Sec3_C PF09763.4 EGC34588.1 - 0.034 12.2 0.1 0.034 12.2 0.0 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec3 Mating_N PF12731.2 EGC34589.1 - 0.035 13.9 0.9 1.6 8.6 0.1 2.6 2 0 0 2 2 2 0 Mating-type protein beta 1 CHD5 PF04420.9 EGC34589.1 - 0.22 11.1 2.4 0.19 11.4 0.4 1.7 2 0 0 2 2 2 0 CHD5-like protein DUF2559 PF10832.3 EGC34589.1 - 0.51 10.1 3.4 0.2 11.4 0.5 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2559) EF-hand_7 PF13499.1 EGC34589.1 - 0.62 10.2 6.2 4.1 7.6 4.3 2.3 1 1 0 1 1 1 0 EF-hand domain pair Phage_XkdX PF09693.5 EGC34589.1 - 0.75 9.3 6.2 9.5 5.8 0.0 3.2 3 0 0 3 3 3 0 Phage uncharacterised protein (Phage_XkdX) EGF_2 PF07974.8 EGC34590.1 - 1.1e-07 31.8 45.3 0.0011 19.0 8.8 4.0 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.19 EGC34590.1 - 0.0099 15.7 4.1 0.0099 15.7 2.8 4.0 3 0 0 3 3 3 2 Laminin EGF-like (Domains III and V) HSP20 PF00011.16 EGC34591.1 - 1.3e-13 50.6 2.5 4.3e-06 26.5 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.11 EGC34591.1 - 0.32 11.5 5.8 0.15 12.6 0.5 2.7 2 1 1 3 3 3 0 CS domain DUF2807 PF10988.3 EGC34591.1 - 1.8 8.0 10.0 1.4 8.4 2.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2807) Pro_isomerase PF00160.16 EGC34592.1 - 7.9e-49 165.8 0.7 8.8e-49 165.6 0.5 1.0 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD SnoaL_2 PF12680.2 EGC34593.1 - 6.3e-06 26.5 0.0 7.5e-06 26.2 0.0 1.1 1 0 0 1 1 1 1 SnoaL-like domain SnoaL PF07366.7 EGC34593.1 - 0.00062 19.3 0.3 0.0017 17.8 0.2 1.6 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase DUF4440 PF14534.1 EGC34593.1 - 0.0035 17.5 0.0 0.0042 17.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4440) DUF3271 PF11675.3 EGC34593.1 - 0.021 13.9 0.8 0.021 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3271) HopJ PF08888.6 EGC34593.1 - 0.085 12.8 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 HopJ type III effector protein RRM_1 PF00076.17 EGC34594.1 - 1.1e-19 69.8 1.2 3.4e-09 36.2 0.5 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34594.1 - 4e-14 52.1 7.9 2e-11 43.5 0.1 3.0 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34594.1 - 4.3e-13 49.0 0.8 7.7e-06 25.8 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DbpA PF03880.10 EGC34594.1 - 8.5e-08 31.7 0.9 0.00012 21.6 0.4 2.5 2 0 0 2 2 2 2 DbpA RNA binding domain RRM_5 PF13893.1 EGC34595.1 - 1.7e-35 120.6 0.3 4.1e-13 48.9 0.0 4.0 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34595.1 - 5.1e-23 80.8 0.2 6.8e-09 35.5 0.0 4.3 5 0 0 5 5 5 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC34595.1 - 6.1e-17 61.0 0.0 0.00012 21.6 0.0 5.0 5 0 0 5 5 5 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) UCH PF00443.24 EGC34596.1 - 9.8e-51 172.4 4.5 9.8e-51 172.4 3.1 5.4 6 0 0 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC34596.1 - 6.9e-28 97.9 1.4 6.9e-28 97.9 1.0 4.7 6 1 0 6 6 6 1 Ubiquitin carboxyl-terminal hydrolase FokI_N PF02981.10 EGC34597.1 - 0.16 11.5 1.0 0.36 10.4 0.4 1.7 1 1 1 2 2 2 0 Restriction endonuclease FokI, recognition domain Transferase PF02458.10 EGC34598.1 - 1.7e-10 39.9 0.0 2.4e-10 39.4 0.0 1.2 1 0 0 1 1 1 1 Transferase family DUF2846 PF11008.3 EGC34598.1 - 0.015 15.1 1.3 2.3 8.0 0.0 2.7 2 1 0 2 2 2 0 Protein of unknown function (DUF2846) Clat_adaptor_s PF01217.15 EGC34599.1 - 9.1e-46 155.1 4.2 1.2e-45 154.7 2.9 1.2 1 0 0 1 1 1 1 Clathrin adaptor complex small chain AP-5_subunit_s1 PF15001.1 EGC34599.1 - 0.0043 17.0 0.1 0.006 16.5 0.1 1.3 1 0 0 1 1 1 1 AP-5 complex subunit sigma-1 Methyltransf_31 PF13847.1 EGC34600.1 - 5.2e-12 45.5 0.2 8e-12 45.0 0.1 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC34600.1 - 3.7e-11 43.5 0.0 5.2e-11 43.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC34600.1 - 1.4e-08 34.8 0.0 1.7e-08 34.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC34600.1 - 4.2e-08 33.5 0.0 7.2e-08 32.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC34600.1 - 7.6e-07 29.4 0.0 1.1e-06 28.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC34600.1 - 1.6e-06 27.5 0.0 2.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EGC34600.1 - 2.2e-06 27.3 0.0 3.4e-06 26.7 0.0 1.2 1 0 0 1 1 1 1 Putative RNA methylase family UPF0020 CMAS PF02353.15 EGC34600.1 - 6.1e-06 25.5 0.0 8.3e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase PrmA PF06325.8 EGC34600.1 - 6.4e-06 25.4 0.1 9.2e-06 24.9 0.1 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EGC34600.1 - 1.2e-05 25.6 0.0 1.7e-05 25.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EGC34600.1 - 3.5e-05 23.4 0.1 5.6e-05 22.7 0.0 1.3 1 0 0 1 1 1 1 DNA methylase Methyltransf_15 PF09445.5 EGC34600.1 - 6.9e-05 22.4 0.2 0.00011 21.8 0.1 1.2 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase DOT1 PF08123.8 EGC34600.1 - 0.00019 20.8 0.0 0.00029 20.2 0.0 1.2 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_23 PF13489.1 EGC34600.1 - 0.00053 19.7 0.0 0.00077 19.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC34600.1 - 0.00083 18.4 0.0 0.0011 18.0 0.0 1.2 1 0 0 1 1 1 1 Putative methyltransferase TehB PF03848.9 EGC34600.1 - 0.0011 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB Met_10 PF02475.11 EGC34600.1 - 0.0015 18.1 0.0 0.0017 17.9 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Ubie_methyltran PF01209.13 EGC34600.1 - 0.0042 16.2 0.1 0.0058 15.7 0.1 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family MetW PF07021.7 EGC34600.1 - 0.0044 16.4 0.0 0.0067 15.8 0.0 1.3 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EGC34600.1 - 0.0067 16.1 0.0 0.0075 15.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGC34600.1 - 0.033 13.7 0.0 0.051 13.1 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase PCMT PF01135.14 EGC34600.1 - 0.05 13.1 0.0 0.074 12.5 0.0 1.2 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_8 PF05148.10 EGC34600.1 - 0.083 12.5 0.2 0.14 11.7 0.0 1.4 2 0 0 2 2 2 0 Hypothetical methyltransferase Profilin PF00235.14 EGC34601.1 - 7.1e-07 29.3 0.3 8.7e-07 29.0 0.2 1.1 1 0 0 1 1 1 1 Profilin HSP20 PF00011.16 EGC34602.1 - 3.7e-16 58.8 0.5 7.6e-16 57.8 0.3 1.5 1 1 0 1 1 1 1 Hsp20/alpha crystallin family CS PF04969.11 EGC34602.1 - 0.084 13.4 2.2 0.085 13.4 0.4 1.9 2 0 0 2 2 2 0 CS domain DDE_Tnp_1_6 PF13751.1 EGC34602.1 - 0.094 12.7 0.0 0.13 12.2 0.0 1.2 1 0 0 1 1 1 0 Transposase DDE domain DUF2807 PF10988.3 EGC34602.1 - 0.62 9.5 4.9 0.22 11.0 0.4 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2807) TLD PF07534.11 EGC34603.1 - 1.1e-36 125.8 0.8 1.1e-36 125.8 0.5 6.0 6 3 2 8 8 8 1 TLD HemN_C PF06969.11 EGC34603.1 - 2.7e-05 24.1 0.4 6.5e-05 22.9 0.3 1.7 1 0 0 1 1 1 1 HemN C-terminal domain Methyltransf_11 PF08241.7 EGC34604.1 - 1.4e-23 83.1 0.0 3.5e-23 81.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC34604.1 - 6.7e-20 71.4 0.0 1e-19 70.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34604.1 - 1e-19 70.6 0.0 2e-19 69.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC34604.1 - 1.1e-16 60.7 0.0 3.4e-16 59.0 0.0 1.8 1 1 1 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGC34604.1 - 3.5e-14 53.3 0.0 1e-13 51.8 0.0 1.8 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34604.1 - 6.3e-13 49.0 0.0 1.3e-11 44.8 0.0 2.5 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC34604.1 - 1.7e-12 47.4 0.0 3.7e-12 46.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC34604.1 - 1.7e-12 47.5 0.0 3.8e-12 46.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC34604.1 - 2.3e-11 43.2 0.0 3.8e-11 42.5 0.0 1.3 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase MetW PF07021.7 EGC34604.1 - 6e-05 22.5 0.0 0.00011 21.6 0.0 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Methyltransf_15 PF09445.5 EGC34604.1 - 0.00037 20.0 0.0 0.00082 18.9 0.0 1.6 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase COXG PF06240.8 EGC34604.1 - 0.00037 20.1 0.3 0.00066 19.3 0.2 1.3 1 0 0 1 1 1 1 Carbon monoxide dehydrogenase subunit G (CoxG) Polyketide_cyc2 PF10604.4 EGC34604.1 - 0.00039 20.6 0.0 0.00079 19.6 0.0 1.5 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport MTS PF05175.9 EGC34604.1 - 0.00044 19.6 0.0 0.00096 18.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain UPF0020 PF01170.13 EGC34604.1 - 0.00066 19.3 0.0 0.0017 17.9 0.0 1.7 2 0 0 2 2 2 1 Putative RNA methylase family UPF0020 Methyltransf_8 PF05148.10 EGC34604.1 - 0.00082 19.0 0.0 0.035 13.7 0.0 2.6 2 1 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_29 PF03141.11 EGC34604.1 - 0.0018 16.6 0.0 0.0033 15.8 0.0 1.4 1 1 0 1 1 1 1 Putative S-adenosyl-L-methionine-dependent methyltransferase DOT1 PF08123.8 EGC34604.1 - 0.01 15.1 0.0 0.024 13.9 0.0 1.5 1 0 0 1 1 1 0 Histone methylation protein DOT1 Methyltransf_32 PF13679.1 EGC34604.1 - 0.018 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGC34604.1 - 0.043 13.3 0.0 0.077 12.5 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Thiolase_N PF00108.18 EGC34605.1 - 0.021 13.8 0.0 0.032 13.2 0.0 1.2 1 0 0 1 1 1 0 Thiolase, N-terminal domain zf-met2 PF12907.2 EGC34606.1 - 5.1e-17 61.5 4.7 6.5e-17 61.2 3.2 1.2 1 0 0 1 1 1 1 Zinc-binding 4F5 PF04419.9 EGC34606.1 - 4.6e-08 33.6 11.1 4.6e-08 33.6 7.7 1.5 2 0 0 2 2 2 1 4F5 protein family Rpr2 PF04032.11 EGC34606.1 - 0.021 14.6 0.8 0.026 14.3 0.6 1.1 1 0 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain DUF726 PF05277.7 EGC34607.1 - 1.1e-67 228.4 4.1 7.8e-65 219.0 0.4 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF726) VPS9 PF02204.13 EGC34607.1 - 3.3e-26 91.3 0.4 1.5e-25 89.2 0.0 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Abhydrolase_5 PF12695.2 EGC34607.1 - 0.21 11.3 0.0 0.41 10.3 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family DPBB_1 PF03330.13 EGC34608.1 - 2.1e-12 46.8 0.0 5.8e-12 45.4 0.0 1.7 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EGC34608.1 - 0.00079 19.1 0.3 0.0016 18.1 0.2 1.5 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 EGC34608.1 - 0.0018 17.9 0.1 0.0035 17.0 0.0 1.5 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EGC34608.1 - 0.022 14.7 0.1 0.055 13.4 0.1 1.7 1 0 0 1 1 1 0 Cerato-platanin CPSase_L_D2 PF02786.12 EGC34609.1 - 1.4e-72 243.3 0.2 2.6e-72 242.5 0.1 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGC34609.1 - 2.1e-42 143.6 0.2 5.8e-42 142.2 0.1 1.8 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGC34609.1 - 2.3e-37 127.2 0.0 7e-37 125.6 0.0 1.8 2 0 0 2 2 2 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGC34609.1 - 6.2e-18 64.2 1.0 8.1e-17 60.6 0.3 2.8 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGC34609.1 - 1.1e-15 57.8 0.0 2.7e-15 56.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGC34609.1 - 1.8e-13 49.9 0.1 2.9e-13 49.2 0.1 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon Dala_Dala_lig_C PF07478.8 EGC34609.1 - 1.5e-09 37.5 0.0 4.7e-09 35.9 0.0 1.8 1 1 0 1 1 1 1 D-ala D-ala ligase C-terminus ATP-grasp PF02222.17 EGC34609.1 - 9.5e-08 31.5 0.1 2.8e-07 30.0 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_3 PF02655.9 EGC34609.1 - 1.4e-07 31.5 0.0 7.7e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGC34609.1 - 5.5e-05 22.7 0.6 0.014 15.0 0.0 2.6 1 1 1 2 2 2 1 Biotin-lipoyl like RimK PF08443.6 EGC34609.1 - 0.0005 19.5 0.1 0.0023 17.4 0.0 2.2 1 1 0 1 1 1 1 RimK-like ATP-grasp domain ATPgrasp_ST PF14397.1 EGC34609.1 - 0.022 13.8 0.0 0.052 12.6 0.0 1.7 1 0 0 1 1 1 0 Sugar-transfer associated ATP-grasp HlyD_3 PF13437.1 EGC34609.1 - 0.025 14.9 0.2 0.56 10.5 0.0 2.9 2 1 1 3 3 3 0 HlyD family secretion protein ATP-grasp_5 PF13549.1 EGC34609.1 - 0.068 12.3 0.0 0.24 10.6 0.0 1.9 2 0 0 2 2 2 0 ATP-grasp domain SNARE_assoc PF09335.6 EGC34610.1 - 7.6e-31 106.8 5.5 7.6e-31 106.8 3.8 2.2 3 0 0 3 3 3 1 SNARE associated Golgi protein DUF1772 PF08592.6 EGC34610.1 - 0.028 14.1 0.2 0.48 10.1 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) OSTbeta PF15048.1 EGC34610.1 - 0.28 11.2 1.4 2.4 8.2 0.2 2.3 2 0 0 2 2 2 0 Organic solute transporter subunit beta protein RseC_MucC PF04246.7 EGC34610.1 - 0.4 10.2 8.7 0.46 10.0 1.9 2.7 2 1 0 3 3 3 0 Positive regulator of sigma(E), RseC/MucC BPD_transp_1 PF00528.17 EGC34610.1 - 6.1 6.3 23.8 0.22 11.0 11.3 2.2 1 1 1 2 2 2 0 Binding-protein-dependent transport system inner membrane component Brr6_like_C_C PF10104.4 EGC34610.1 - 8.9 5.8 11.9 36 3.8 0.6 4.3 3 1 1 4 4 4 0 Di-sulfide bridge nucleocytoplasmic transport domain PUF PF00806.14 EGC34611.1 - 2e-38 127.7 24.0 3.1e-06 26.3 0.2 8.6 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat Tenui_NCP PF04876.7 EGC34611.1 - 0.0029 17.1 4.3 0.004 16.7 0.6 2.8 1 1 1 3 3 3 1 Tenuivirus major non-capsid protein CPL PF08144.6 EGC34611.1 - 0.11 12.2 2.3 33 4.2 0.1 3.7 2 1 0 3 3 3 0 CPL (NUC119) domain G-patch PF01585.18 EGC34612.1 - 7.4e-12 44.8 1.1 1.8e-11 43.6 0.8 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGC34612.1 - 1.6e-06 27.8 0.5 1.6e-06 27.8 0.4 4.8 2 1 1 3 3 3 1 DExH-box splicing factor binding site DUF605 PF04652.11 EGC34612.1 - 0.26 10.6 42.2 0.35 10.2 29.3 1.1 1 0 0 1 1 1 0 Vta1 like MIP-T3 PF10243.4 EGC34612.1 - 0.58 8.5 59.6 0.72 8.2 41.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Daxx PF03344.10 EGC34612.1 - 0.91 7.9 45.9 1.1 7.6 31.8 1.1 1 0 0 1 1 1 0 Daxx Family Atrophin-1 PF03154.10 EGC34612.1 - 1.1 7.2 51.4 1.7 6.6 35.6 1.3 1 0 0 1 1 1 0 Atrophin-1 family Utp14 PF04615.8 EGC34612.1 - 3.6 5.6 57.4 4.4 5.3 39.8 1.1 1 0 0 1 1 1 0 Utp14 protein Macoilin PF09726.4 EGC34612.1 - 3.7 5.7 59.0 4.6 5.4 40.9 1.1 1 0 0 1 1 1 0 Transmembrane protein ADH_N PF08240.7 EGC34614.1 - 4.1e-26 90.8 2.9 8.6e-26 89.8 2.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC34614.1 - 1.6e-18 66.5 0.1 2.7e-18 65.7 0.1 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC34614.1 - 0.0029 18.4 0.0 0.0054 17.6 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGC34614.1 - 0.0059 15.7 0.1 0.0096 15.0 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGC34614.1 - 0.0083 16.1 0.1 0.013 15.4 0.0 1.3 1 0 0 1 1 1 1 TrkA-N domain UDPG_MGDP_dh_N PF03721.9 EGC34614.1 - 0.024 14.0 0.2 0.038 13.3 0.1 1.3 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ThiF PF00899.16 EGC34614.1 - 0.048 13.4 0.2 0.11 12.3 0.2 1.6 1 0 0 1 1 1 0 ThiF family FYVE PF01363.16 EGC34615.1 - 7.5e-21 73.8 5.9 1.4e-20 72.9 4.1 1.5 1 0 0 1 1 1 1 FYVE zinc finger Pkinase PF00069.20 EGC34615.1 - 4.5e-11 42.3 2.1 1.8e-10 40.4 1.5 1.8 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34615.1 - 6.2e-11 41.8 1.3 1.7e-10 40.4 0.9 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase WH2 PF02205.15 EGC34615.1 - 0.16 11.6 0.2 0.16 11.6 0.1 2.6 2 1 0 2 2 2 0 WH2 motif FYVE_2 PF02318.11 EGC34615.1 - 0.19 11.6 5.4 0.39 10.6 3.7 1.4 1 0 0 1 1 1 0 FYVE-type zinc finger HypA PF01155.14 EGC34615.1 - 1.7 8.3 6.4 2.1 8.0 2.5 2.1 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family zf-RING_5 PF14634.1 EGC34615.1 - 2.7 7.8 8.9 6.9 6.4 6.2 1.8 1 0 0 1 1 1 0 zinc-RING finger domain Lipoprotein_7 PF01540.11 EGC34616.1 - 0.00011 21.4 1.4 0.00012 21.2 1.0 1.0 1 0 0 1 1 1 1 Adhesin lipoprotein DUF869 PF05911.6 EGC34616.1 - 0.00042 18.6 2.0 0.00049 18.4 1.4 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) Prominin PF05478.6 EGC34616.1 - 0.017 12.7 1.1 0.019 12.5 0.8 1.0 1 0 0 1 1 1 0 Prominin Lyase_1 PF00206.15 EGC34616.1 - 0.028 13.6 1.2 0.032 13.4 0.8 1.1 1 0 0 1 1 1 0 Lyase DegS PF05384.6 EGC34616.1 - 0.04 13.1 0.6 0.96 8.6 0.0 2.0 1 1 1 2 2 2 0 Sensor protein DegS DUF342 PF03961.8 EGC34616.1 - 0.052 11.9 1.3 0.063 11.6 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) THOC7 PF05615.8 EGC34616.1 - 0.085 13.1 0.2 0.1 12.8 0.2 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 CLU PF13236.1 EGC34617.1 - 2.3e-88 295.3 0.0 2.3e-88 295.3 0.0 1.9 2 0 0 2 2 2 1 Clustered mitochondria eIF3_p135 PF12807.2 EGC34617.1 - 7.6e-50 169.1 0.1 7.6e-50 169.1 0.1 4.8 4 1 1 5 5 3 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EGC34617.1 - 3.5e-27 94.1 0.0 3.7e-12 46.0 0.0 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat CLU_N PF15044.1 EGC34617.1 - 2.6e-21 75.5 0.1 1.3e-20 73.3 0.0 2.4 1 0 0 1 1 1 1 Mitochondrial function, CLU-N-term TPR_10 PF13374.1 EGC34617.1 - 4.1e-15 55.1 0.0 0.012 15.5 0.0 5.4 5 0 0 5 5 5 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34617.1 - 1.3e-10 40.7 0.1 0.00056 19.5 0.0 3.6 3 0 0 3 3 3 2 TPR repeat DUF727 PF05303.7 EGC34617.1 - 2.4e-06 27.2 0.0 7.8e-06 25.6 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF727) TPR_2 PF07719.12 EGC34617.1 - 2.7e-06 26.8 0.1 26 5.0 0.0 5.7 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC34617.1 - 3.3e-06 26.4 2.9 4.3 7.0 0.1 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34617.1 - 0.00015 22.3 0.0 0.016 15.8 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC34617.1 - 0.0005 19.6 0.3 4.3 7.3 0.0 4.7 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC34617.1 - 0.015 15.0 0.3 2.4 8.1 0.0 4.2 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF3367 PF11847.3 EGC34617.1 - 0.81 7.5 5.5 1.6 6.5 3.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3367) DLIC PF05783.6 EGC34618.1 - 7.4e-91 305.1 13.1 8.3e-62 209.3 2.5 2.1 1 1 1 2 2 2 2 Dynein light intermediate chain (DLIC) AAA_16 PF13191.1 EGC34618.1 - 0.027 14.4 0.1 0.12 12.3 0.0 2.1 2 1 1 3 3 3 0 AAA ATPase domain Miro PF08477.8 EGC34618.1 - 0.033 14.6 1.7 0.11 12.9 0.0 2.7 3 0 0 3 3 3 0 Miro-like protein Glyco_hydro_3 PF00933.16 EGC34619.1 - 6.6e-69 232.1 0.0 8.7e-69 231.7 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 N terminal domain Glyco_hydro_3_C PF01915.17 EGC34619.1 - 2.3e-48 164.7 0.0 3.9e-48 163.9 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 3 C-terminal domain Fn3-like PF14310.1 EGC34619.1 - 1.7e-15 56.6 0.0 3.8e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 Fibronectin type III-like domain DUF11 PF01345.13 EGC34619.1 - 0.00073 19.5 0.5 0.0025 17.8 0.1 2.0 2 0 0 2 2 2 1 Domain of unknown function DUF11 FNIP PF05725.7 EGC34620.1 - 1.1e-84 278.1 86.5 1.7e-14 53.4 0.4 12.9 6 2 9 16 16 16 16 FNIP Repeat EGF_CA PF07645.10 EGC34621.1 - 6e-106 346.2 251.4 1.2e-09 38.0 5.3 16.2 16 0 0 16 16 16 14 Calcium-binding EGF domain FXa_inhibition PF14670.1 EGC34621.1 - 2e-98 322.1 255.3 2.6e-12 46.6 8.6 15.8 16 0 0 16 16 16 13 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EGC34621.1 - 2.7e-92 301.8 121.6 1.6e-09 37.2 0.4 15.2 14 0 0 14 14 14 14 Complement Clr-like EGF-like EGF_3 PF12947.2 EGC34621.1 - 3e-26 91.0 213.4 0.0014 18.5 8.5 17.4 18 0 0 18 18 18 14 EGF domain EGF PF00008.22 EGC34621.1 - 6.8e-14 51.5 208.6 0.015 15.2 4.7 17.1 16 0 0 16 16 16 14 EGF-like domain TIG PF01833.19 EGC34621.1 - 2e-08 34.1 23.9 3.6e-05 23.6 0.2 6.0 5 0 0 5 5 5 3 IPT/TIG domain hEGF PF12661.2 EGC34621.1 - 0.004 17.1 84.9 4.9 7.4 0.1 15.8 15 0 0 15 15 15 7 Human growth factor-like EGF DUF1191 PF06697.7 EGC34621.1 - 0.025 13.3 0.0 0.055 12.2 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) GBP PF02263.14 EGC34622.1 - 6.6e-46 156.4 0.5 6.6e-46 156.4 0.4 2.8 3 0 0 3 3 3 1 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EGC34622.1 - 0.00048 20.0 0.4 0.0024 17.8 0.0 2.3 2 1 0 2 2 2 1 50S ribosome-binding GTPase SLAC1 PF03595.12 EGC34623.1 - 4.4e-17 61.7 46.5 5.5e-17 61.4 32.2 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel DEP PF00610.16 EGC34623.1 - 0.00036 20.2 0.0 0.00091 18.9 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) SLAC1 PF03595.12 EGC34624.1 - 2.6e-22 78.9 43.5 3.1e-22 78.6 30.1 1.1 1 0 0 1 1 1 1 Voltage-dependent anion channel Hum_adeno_E3A PF05393.6 EGC34624.1 - 6.1 6.5 9.5 0.73 9.5 0.3 3.3 3 1 1 4 4 4 0 Human adenovirus early E3A glycoprotein Glyco_hydro_18 PF00704.23 EGC34625.1 - 2.7e-38 132.3 0.0 3.2e-38 132.0 0.0 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 FNIP PF05725.7 EGC34626.1 - 3.5e-26 90.8 84.5 1.4e-08 34.5 0.7 9.5 8 1 2 10 10 10 7 FNIP Repeat Glucosamine_iso PF01182.15 EGC34627.1 - 1.9e-41 142.0 0.0 2.3e-41 141.7 0.0 1.0 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase bPH_3 PF14470.1 EGC34628.1 - 1.2e-14 54.2 2.8 1.8e-07 31.3 0.9 2.5 2 0 0 2 2 2 2 Bacterial PH domain GRAM PF02893.15 EGC34628.1 - 4e-10 39.0 0.6 0.00026 20.4 0.1 2.6 2 0 0 2 2 2 2 GRAM domain DUF605 PF04652.11 EGC34628.1 - 0.0052 16.2 14.7 0.0063 15.9 10.2 1.2 1 0 0 1 1 1 1 Vta1 like Totivirus_coat PF05518.6 EGC34628.1 - 5.6 4.6 6.3 7.7 4.2 4.4 1.1 1 0 0 1 1 1 0 Totivirus coat protein AhpC-TSA PF00578.16 EGC34629.1 - 7.7e-32 109.5 0.1 1e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA family 1-cysPrx_C PF10417.4 EGC34629.1 - 5.5e-15 54.7 0.2 1.3e-14 53.5 0.1 1.7 1 0 0 1 1 1 1 C-terminal domain of 1-Cys peroxiredoxin Redoxin PF08534.5 EGC34629.1 - 5e-10 39.1 0.0 6.8e-10 38.6 0.0 1.2 1 0 0 1 1 1 1 Redoxin Thioredoxin_8 PF13905.1 EGC34629.1 - 0.0035 17.4 0.1 0.0059 16.7 0.0 1.4 1 0 0 1 1 1 1 Thioredoxin-like ADH_N PF08240.7 EGC34630.1 - 1.2e-20 73.3 1.7 1.2e-20 73.3 1.2 1.7 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC34630.1 - 4.9e-11 42.2 0.0 8e-11 41.5 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGC34630.1 - 0.05 12.7 0.2 0.09 11.9 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain DUF2383 PF09537.5 EGC34631.1 - 5e-14 52.4 0.0 9e-14 51.6 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF2383) DUF892 PF05974.7 EGC34631.1 - 2.1e-07 30.9 0.4 2.6e-05 24.0 0.0 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF892) Ferritin PF00210.19 EGC34631.1 - 1.7e-05 24.5 2.0 0.00065 19.4 0.3 2.1 2 0 0 2 2 2 2 Ferritin-like domain DUF3231 PF11553.3 EGC34631.1 - 0.00025 20.5 0.2 0.0015 18.0 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3231) S4 PF01479.20 EGC34632.1 - 0.0003 20.1 0.0 0.00096 18.5 0.0 1.9 1 0 0 1 1 1 1 S4 domain Ribosomal_S4 PF00163.14 EGC34632.1 - 0.002 18.4 1.7 0.0038 17.5 0.9 1.7 2 0 0 2 2 2 1 Ribosomal protein S4/S9 N-terminal domain YcbB PF08664.5 EGC34632.1 - 0.085 12.6 0.1 0.18 11.5 0.1 1.5 1 1 0 1 1 1 0 YcbB domain UPF0175 PF03683.8 EGC34632.1 - 0.099 12.1 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0175) AAA PF00004.24 EGC34633.1 - 1.6e-16 60.6 0.0 2.8e-16 59.9 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGC34633.1 - 6.2e-15 54.9 0.0 2e-14 53.3 0.0 1.9 2 0 0 2 2 2 1 Replication factor C C-terminal domain DNA_pol3_delta2 PF13177.1 EGC34633.1 - 4.4e-11 42.7 0.1 4.1e-09 36.3 0.0 2.7 2 1 0 2 2 2 1 DNA polymerase III, delta subunit AAA_22 PF13401.1 EGC34633.1 - 1.9e-06 28.0 0.1 0.0013 18.8 0.0 2.5 1 1 1 2 2 2 1 AAA domain Rad17 PF03215.10 EGC34633.1 - 1.2e-05 24.2 0.1 0.00041 19.1 0.0 2.8 1 1 1 2 2 2 1 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGC34633.1 - 2.2e-05 24.3 0.0 5e-05 23.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGC34633.1 - 9e-05 22.0 0.0 0.1 12.0 0.0 2.5 2 1 1 3 3 3 2 AAA-like domain AAA_19 PF13245.1 EGC34633.1 - 0.00012 21.7 0.0 0.00022 20.8 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_16 PF13191.1 EGC34633.1 - 0.00015 21.7 0.0 0.00033 20.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_3 PF07726.6 EGC34633.1 - 0.00024 20.7 0.0 0.00046 19.8 0.0 1.4 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGC34633.1 - 0.00037 19.6 0.0 0.00079 18.5 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGC34633.1 - 0.00043 21.0 0.0 0.001 19.8 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGC34633.1 - 0.00056 19.5 0.0 0.00093 18.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGC34633.1 - 0.00093 18.9 0.0 0.0029 17.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) AAA_24 PF13479.1 EGC34633.1 - 0.001 18.7 0.0 0.002 17.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain IstB_IS21 PF01695.12 EGC34633.1 - 0.0012 18.2 0.0 0.0036 16.7 0.0 1.7 1 1 0 1 1 1 1 IstB-like ATP binding protein AAA_18 PF13238.1 EGC34633.1 - 0.0023 18.2 0.0 0.006 16.8 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGC34633.1 - 0.0033 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_23 PF13476.1 EGC34633.1 - 0.0039 17.5 0.3 0.0039 17.5 0.2 1.9 2 1 0 2 2 1 1 AAA domain AAA_30 PF13604.1 EGC34633.1 - 0.0059 16.2 0.0 0.017 14.7 0.0 1.7 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGC34633.1 - 0.008 15.1 0.0 0.014 14.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGC34633.1 - 0.0088 16.0 0.0 0.015 15.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC34633.1 - 0.012 15.4 0.0 0.023 14.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGC34633.1 - 0.013 15.6 0.0 0.028 14.5 0.0 1.7 1 0 0 1 1 1 0 RNA helicase MobB PF03205.9 EGC34633.1 - 0.013 15.1 0.0 0.03 14.0 0.0 1.6 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EGC34633.1 - 0.034 13.6 0.0 0.084 12.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain Arch_ATPase PF01637.13 EGC34633.1 - 0.04 13.6 0.0 0.094 12.3 0.0 1.5 1 1 0 1 1 1 0 Archaeal ATPase ABC_tran PF00005.22 EGC34633.1 - 0.04 14.2 0.0 0.12 12.6 0.0 1.8 2 0 0 2 2 1 0 ABC transporter Mg_chelatase PF01078.16 EGC34633.1 - 0.048 12.8 0.0 0.15 11.1 0.0 1.8 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Thymidylate_kin PF02223.12 EGC34633.1 - 0.055 12.8 0.0 0.71 9.2 0.0 2.2 1 1 0 2 2 2 0 Thymidylate kinase PIF1 PF05970.9 EGC34633.1 - 0.064 12.1 0.0 1.6 7.5 0.0 2.2 2 0 0 2 2 2 0 PIF1-like helicase AAA_25 PF13481.1 EGC34633.1 - 0.068 12.5 0.0 0.24 10.7 0.0 1.9 1 1 0 1 1 1 0 AAA domain L27_N PF09060.5 EGC34633.1 - 0.069 12.9 0.0 0.24 11.2 0.0 1.9 2 0 0 2 2 2 0 L27_N Bac_DnaA PF00308.13 EGC34633.1 - 0.071 12.7 0.0 0.12 11.9 0.0 1.5 1 0 0 1 1 1 0 Bacterial dnaA protein DEAD PF00270.24 EGC34633.1 - 0.074 12.5 0.1 1.7 8.0 0.0 2.5 1 1 1 2 2 2 0 DEAD/DEAH box helicase SRP54 PF00448.17 EGC34633.1 - 0.083 12.3 0.0 0.16 11.3 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EGC34633.1 - 0.093 12.1 0.0 0.19 11.1 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family Zeta_toxin PF06414.7 EGC34633.1 - 0.15 11.1 0.0 0.34 9.9 0.0 1.5 2 0 0 2 2 1 0 Zeta toxin UPRTase PF14681.1 EGC34634.1 - 2.1e-81 272.0 0.0 2.4e-81 271.9 0.0 1.0 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase Pribosyltran PF00156.22 EGC34634.1 - 5.1e-08 32.6 0.1 1.3e-07 31.3 0.0 1.8 1 1 0 1 1 1 1 Phosphoribosyl transferase domain PRTase_2 PF15609.1 EGC34634.1 - 0.099 11.9 0.0 0.15 11.3 0.0 1.2 1 0 0 1 1 1 0 Phosphoribosyl transferase DNA_pol_E_B PF04042.11 EGC34635.1 - 8.8e-40 136.1 0.1 2e-39 135.0 0.1 1.6 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B RRM_1 PF00076.17 EGC34635.1 - 0.077 12.6 0.3 8.5 6.0 0.1 2.5 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4482 PF14818.1 EGC34635.1 - 0.8 10.3 5.4 2.2 8.9 3.7 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4482) DUF3446 PF11928.3 EGC34635.1 - 1.6 8.9 12.2 1.7 8.8 6.7 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) ArfGap PF01412.13 EGC34637.1 - 2.6e-33 114.2 0.2 2.6e-33 114.2 0.1 4.4 4 0 0 4 4 4 1 Putative GTPase activating protein for Arf Alpha-amylase PF00128.19 EGC34638.1 - 4.3e-65 220.1 0.6 4.3e-65 220.1 0.4 1.9 2 0 0 2 2 2 1 Alpha amylase, catalytic domain DUF1966 PF09260.6 EGC34638.1 - 0.0011 19.0 0.0 0.0048 16.9 0.0 2.1 2 0 0 2 2 2 1 Domain of unknown function (DUF1966) GHL6 PF14871.1 EGC34638.1 - 0.075 13.0 0.0 0.37 10.7 0.0 2.2 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 6 DUF3430 PF11912.3 EGC34639.1 - 0.029 14.1 20.4 0.25 11.1 14.1 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) CarboxypepD_reg PF13620.1 EGC34640.1 - 1.6e-22 79.3 0.1 0.0062 16.5 0.0 8.5 9 0 0 9 9 9 6 Carboxypeptidase regulatory-like domain Methyltransf_26 PF13659.1 EGC34641.1 - 2.2e-13 50.2 0.0 3.3e-13 49.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34641.1 - 8.6e-07 28.6 0.0 1.3e-06 28.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34641.1 - 0.00024 21.5 0.0 0.00024 21.5 0.0 3.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_24 PF13578.1 EGC34641.1 - 0.00072 20.3 0.0 0.0023 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC34641.1 - 0.0013 19.0 0.0 0.0027 18.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC34641.1 - 0.014 14.8 0.0 0.025 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGC34641.1 - 0.026 15.1 0.0 0.043 14.3 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Mem_trans PF03547.13 EGC34641.1 - 0.042 12.1 0.5 0.059 11.6 0.3 1.2 1 0 0 1 1 1 0 Membrane transport protein Methyltransf_11 PF08241.7 EGC34641.1 - 0.071 13.6 0.0 0.14 12.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain p450 PF00067.17 EGC34642.1 - 3.8e-94 315.8 0.0 4.3e-94 315.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UCH PF00443.24 EGC34643.1 - 2.5e-49 167.8 5.7 2.5e-49 167.8 4.0 6.2 7 2 0 7 7 7 1 Ubiquitin carboxyl-terminal hydrolase PIP5K PF01504.13 EGC34645.1 - 1.6e-87 292.8 0.6 3.2e-87 291.8 0.4 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF3439 PF11921.3 EGC34645.1 - 0.3 10.8 2.4 0.8 9.4 1.6 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Menin PF05053.8 EGC34645.1 - 2.4 6.2 11.9 3.4 5.7 8.2 1.2 1 0 0 1 1 1 0 Menin Pkinase PF00069.20 EGC34646.1 - 7.4e-29 100.6 0.1 8.1e-29 100.5 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34646.1 - 1.3e-17 63.7 0.0 1.4e-17 63.5 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC34646.1 - 0.0026 16.7 0.0 0.0037 16.2 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC34646.1 - 0.058 12.4 0.4 0.079 12.0 0.3 1.1 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC34646.1 - 0.089 12.5 0.4 0.11 12.1 0.3 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.7 EGC34647.1 - 1.6e-60 200.8 112.6 1.1e-08 34.9 0.6 16.6 9 3 12 21 21 21 19 FNIP Repeat Pkinase PF00069.20 EGC34647.1 - 7.3e-55 185.9 3.4 2.4e-28 98.9 0.3 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34647.1 - 9.4e-39 133.0 0.0 1.3e-19 70.2 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase APH PF01636.18 EGC34647.1 - 3.3e-06 27.0 0.2 0.0079 15.9 0.0 2.7 2 1 0 3 3 3 2 Phosphotransferase enzyme family Kdo PF06293.9 EGC34647.1 - 0.00011 21.3 0.1 0.029 13.4 0.0 2.2 2 0 0 2 2 2 2 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC34647.1 - 0.0015 17.9 1.0 0.11 11.8 0.1 2.5 2 0 0 2 2 2 1 RIO1 family Kinase-like PF14531.1 EGC34647.1 - 0.016 14.1 0.0 1.3 7.9 0.0 2.3 2 0 0 2 2 2 0 Kinase-like Pkinase PF00069.20 EGC34648.1 - 4.8e-73 245.5 13.9 5.2e-42 143.7 0.0 4.9 4 2 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34648.1 - 3.5e-40 137.7 0.4 3.8e-20 72.0 0.0 4.5 3 1 0 3 3 3 3 Protein tyrosine kinase tRNA-synt_His PF13393.1 EGC34648.1 - 4.8e-19 68.5 0.0 8.7e-19 67.6 0.0 1.3 1 0 0 1 1 1 1 Histidyl-tRNA synthetase HGTP_anticodon2 PF12745.2 EGC34648.1 - 9.2e-16 57.7 6.8 9.2e-16 57.7 4.7 5.8 5 2 0 5 5 5 1 Anticodon binding domain of tRNAs RWD PF05773.17 EGC34648.1 - 6.1e-14 51.8 0.3 6.1e-14 51.8 0.2 3.4 4 0 0 4 4 4 1 RWD domain HGTP_anticodon PF03129.15 EGC34648.1 - 3.8e-06 26.7 0.0 1.1e-05 25.2 0.0 1.9 1 0 0 1 1 1 1 Anticodon binding domain Kdo PF06293.9 EGC34648.1 - 0.0035 16.4 0.2 0.016 14.2 0.0 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC34648.1 - 0.0061 15.5 0.1 0.02 13.8 0.0 1.9 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC34648.1 - 0.0082 15.8 0.0 0.057 13.1 0.0 2.0 2 0 0 2 2 2 1 Phosphotransferase enzyme family SNARE PF05739.14 EGC34649.1 - 6.6e-12 44.9 10.6 3.8e-07 29.6 3.1 2.6 2 0 0 2 2 2 2 SNARE domain GRAM PF02893.15 EGC34649.1 - 6.3e-10 38.4 0.1 1.2e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.3 EGC34649.1 - 2.7e-08 33.7 6.8 7.1e-08 32.4 0.4 2.7 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Perilipin PF03036.11 EGC34649.1 - 0.014 14.2 0.2 3 6.5 0.1 2.1 2 0 0 2 2 2 0 Perilipin family Fib_alpha PF08702.5 EGC34649.1 - 2 8.5 6.9 17 5.4 0.1 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 EGC34650.1 - 0.00016 21.9 0.0 0.17 12.2 0.0 3.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) Pox_Ag35 PF03286.9 EGC34651.1 - 0.66 9.4 25.4 0.97 8.9 4.1 2.2 2 0 0 2 2 2 0 Pox virus Ag35 surface protein DUF4611 PF15387.1 EGC34651.1 - 1.5 9.0 17.2 1.3 9.1 6.9 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) LRR_4 PF12799.2 EGC34652.1 - 1e-17 63.3 34.5 4.4e-08 32.5 4.9 4.5 4 1 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC34652.1 - 4.5e-10 39.1 23.1 2e-08 33.8 4.3 3.9 1 1 3 4 4 4 3 Leucine rich repeat LRR_9 PF14580.1 EGC34652.1 - 1.1e-07 31.6 11.2 3.9e-06 26.5 2.6 3.3 1 1 2 3 3 3 2 Leucine-rich repeat LRR_1 PF00560.28 EGC34652.1 - 7.3e-07 28.3 28.3 0.56 10.4 0.2 6.9 6 1 1 7 7 7 6 Leucine Rich Repeat LRR_7 PF13504.1 EGC34652.1 - 8.6e-07 28.1 11.9 1.3 9.4 0.0 6.7 7 0 0 7 7 7 3 Leucine rich repeat DUF2322 PF10084.4 EGC34652.1 - 0.052 13.2 0.2 0.2 11.3 0.0 2.1 2 2 1 3 3 3 0 Uncharacterized protein conserved in bacteria (DUF2322) LRR_6 PF13516.1 EGC34652.1 - 0.39 10.9 24.0 20 5.6 0.1 6.6 6 1 0 6 6 6 0 Leucine Rich repeat LRR_2 PF07723.8 EGC34652.1 - 8.8 7.0 6.7 3.9 8.1 0.1 3.2 3 1 0 3 3 3 0 Leucine Rich Repeat NmrA PF05368.8 EGC34653.1 - 1.4e-40 139.0 0.2 1.7e-40 138.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC34653.1 - 0.00012 22.1 0.0 0.00017 21.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC34653.1 - 0.018 13.7 0.1 0.033 12.8 0.0 1.4 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family DUF3853 PF12964.2 EGC34653.1 - 0.089 12.6 0.0 0.24 11.2 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3853) Ribosomal_L24e PF01246.15 EGC34654.1 - 2e-28 98.0 4.1 4.2e-28 97.0 2.8 1.6 1 0 0 1 1 1 1 Ribosomal protein L24e YlqD PF11068.3 EGC34654.1 - 0.0096 15.9 1.0 0.033 14.2 0.0 1.9 1 1 1 2 2 2 1 YlqD protein DUF3141 PF11339.3 EGC34654.1 - 0.04 12.2 0.0 0.074 11.3 0.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3141) Ras PF00071.17 EGC34655.1 - 1.5e-48 164.2 0.0 1.8e-48 163.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34655.1 - 6e-15 55.7 0.0 1.2e-14 54.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC34655.1 - 1.3e-06 27.8 0.0 1.8e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family DUF1681 PF07933.9 EGC34656.1 - 4.5e-57 192.0 1.2 8.3e-57 191.2 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1681) PAT1 PF09770.4 EGC34656.1 - 7.2 4.7 31.6 9.5 4.3 21.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Dicty_CAR PF05462.6 EGC34657.1 - 3.1e-15 55.8 19.8 3.1e-15 55.8 13.8 2.4 2 1 1 3 3 3 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EGC34657.1 - 1.5e-11 43.8 20.0 2.7e-11 43.0 13.9 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) 7tm_1 PF00001.16 EGC34657.1 - 0.002 17.3 24.4 0.0051 15.9 16.9 1.7 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EGC34657.1 - 0.0034 17.0 2.0 0.0039 16.9 0.1 2.2 2 0 0 2 2 2 1 G protein-coupled glucose receptor regulating Gpa2 C-term Frizzled PF01534.12 EGC34657.1 - 0.03 13.1 25.6 1.5 7.5 13.5 3.0 2 1 0 2 2 2 0 Frizzled/Smoothened family membrane region DUF594 PF04578.8 EGC34657.1 - 0.057 12.8 0.2 0.47 9.9 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function, DUF594 LRR_4 PF12799.2 EGC34658.1 - 8e-12 44.5 15.8 1.9e-08 33.7 2.0 3.4 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC34658.1 - 1.1e-08 34.7 13.6 7.4e-07 28.8 3.5 2.6 1 1 1 2 2 2 2 Leucine rich repeat LRR_9 PF14580.1 EGC34658.1 - 1.3e-06 28.1 0.4 5.1e-06 26.1 0.1 1.8 1 1 1 2 2 2 1 Leucine-rich repeat LRR_7 PF13504.1 EGC34658.1 - 4.2e-06 26.0 8.7 2.7 8.5 0.1 4.8 4 0 0 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EGC34658.1 - 2.1e-05 23.9 10.6 0.33 11.1 0.3 4.6 3 1 1 4 4 4 2 Leucine Rich Repeat LRR_6 PF13516.1 EGC34658.1 - 0.033 14.2 10.0 3.6 7.9 0.1 4.5 4 0 0 4 4 4 0 Leucine Rich repeat DUF3439 PF11921.3 EGC34658.1 - 0.15 11.8 3.5 0.29 10.8 2.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Tir_receptor_C PF07489.6 EGC34658.1 - 0.29 10.8 13.0 0.69 9.6 9.0 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus Ribosomal_L37ae PF01780.14 EGC34659.1 - 4.1e-40 135.5 8.5 4.4e-40 135.4 5.9 1.0 1 0 0 1 1 1 1 Ribosomal L37ae protein family Zn_Tnp_IS1595 PF12760.2 EGC34659.1 - 0.00034 20.3 2.0 0.00053 19.7 1.4 1.4 1 0 0 1 1 1 1 Transposase zinc-ribbon domain A2L_zn_ribbon PF08792.5 EGC34659.1 - 0.027 13.9 3.9 0.51 9.8 0.1 2.2 2 0 0 2 2 2 0 A2L zinc ribbon domain zf-Sec23_Sec24 PF04810.10 EGC34659.1 - 0.03 13.8 1.2 1.9 8.0 0.0 2.2 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger OrfB_Zn_ribbon PF07282.6 EGC34659.1 - 0.036 13.7 1.1 0.049 13.2 0.8 1.3 1 0 0 1 1 1 0 Putative transposase DNA-binding domain zf-FCS PF06467.9 EGC34659.1 - 0.064 12.9 2.6 1.5 8.5 0.1 2.3 2 0 0 2 2 2 0 MYM-type Zinc finger with FCS sequence motif zf-C4_ClpX PF06689.8 EGC34659.1 - 0.066 12.7 0.3 0.066 12.7 0.2 1.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger ZZ PF00569.12 EGC34659.1 - 0.085 12.4 0.9 7.3 6.2 0.0 2.2 2 0 0 2 2 2 0 Zinc finger, ZZ type zf-BED PF02892.10 EGC34659.1 - 0.16 11.7 5.2 0.33 10.7 0.4 2.3 1 1 1 2 2 2 0 BED zinc finger C1_1 PF00130.17 EGC34659.1 - 0.25 11.0 2.1 0.37 10.5 1.4 1.3 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C2H2 PF00096.21 EGC34659.1 - 0.84 10.1 3.0 16 6.1 0.2 2.3 2 0 0 2 2 2 0 Zinc finger, C2H2 type zf-H2C2_2 PF13465.1 EGC34659.1 - 3.2 8.1 5.5 2.7 8.4 0.5 2.2 1 1 1 2 2 2 0 Zinc-finger double domain HSF_DNA-bind PF00447.12 EGC34660.1 - 5.3e-30 103.6 0.3 5.3e-30 103.6 0.2 2.3 2 0 0 2 2 2 1 HSF-type DNA-binding Tmemb_cc2 PF10267.4 EGC34660.1 - 0.0058 15.2 3.6 0.0069 15.0 2.5 1.1 1 0 0 1 1 1 1 Predicted transmembrane and coiled-coil 2 protein Scaffolding_pro PF11418.3 EGC34660.1 - 0.043 14.1 0.8 0.092 13.0 0.6 1.5 1 0 0 1 1 1 0 Phi29 scaffolding protein WXG100 PF06013.7 EGC34660.1 - 0.045 13.7 0.6 0.081 12.9 0.4 1.4 1 0 0 1 1 1 0 Proteins of 100 residues with WXG MbeD_MobD PF04899.7 EGC34660.1 - 0.4 10.6 6.6 0.69 9.8 4.6 1.4 1 0 0 1 1 1 0 MbeD/MobD like DUF3450 PF11932.3 EGC34661.1 - 0.011 14.9 10.3 0.011 14.9 7.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) UPF0227 PF05728.7 EGC34661.1 - 4 7.1 8.6 0.57 9.8 2.0 2.3 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0227) TFIIIC_sub6 PF10419.4 EGC34662.1 - 2.1e-14 52.6 0.2 5e-14 51.4 0.1 1.7 1 0 0 1 1 1 1 TFIIIC subunit XhlA PF10779.4 EGC34663.1 - 1.6 8.6 11.8 5.4 7.0 5.0 2.9 1 1 1 2 2 2 0 Haemolysin XhlA Prefoldin PF02996.12 EGC34664.1 - 3.1e-23 81.7 2.6 3.1e-23 81.7 1.8 1.5 1 1 1 2 2 2 2 Prefoldin subunit Tropomyosin PF00261.15 EGC34664.1 - 0.12 11.3 8.4 1.2 8.1 0.7 2.1 2 0 0 2 2 2 0 Tropomyosin DUF3544 PF12064.3 EGC34664.1 - 0.15 11.8 0.5 0.26 11.0 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3544) DUF948 PF06103.6 EGC34664.1 - 0.67 9.8 5.6 5.3 6.9 0.3 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) HSCB_C PF07743.8 EGC34664.1 - 2.3 8.7 9.4 0.27 11.7 1.3 2.2 2 0 0 2 2 2 0 HSCB C-terminal oligomerisation domain Vps51 PF08700.6 EGC34664.1 - 2.5 8.0 10.0 0.11 12.3 1.5 2.2 2 0 0 2 2 2 0 Vps51/Vps67 Myosin_tail_1 PF01576.14 EGC34664.1 - 2.5 5.7 15.2 2.3 5.8 0.7 2.0 2 0 0 2 2 2 0 Myosin tail DUF1192 PF06698.6 EGC34664.1 - 3.1 7.6 6.7 1.1 9.1 1.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) COG2 PF06148.6 EGC34664.1 - 3.3 7.5 6.2 6 6.7 0.3 2.1 2 0 0 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4200 PF13863.1 EGC34664.1 - 4.9 7.1 17.3 0.47 10.4 1.4 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) Fib_alpha PF08702.5 EGC34664.1 - 7.5 6.6 13.4 4.5 7.3 1.9 2.1 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family RhoGAP PF00620.22 EGC34665.1 - 1.1e-32 112.7 2.8 1.6e-32 112.2 0.3 2.4 2 0 0 2 2 2 1 RhoGAP domain RCC1 PF00415.13 EGC34665.1 - 1e-28 99.2 18.4 8.9e-11 41.8 0.0 8.1 7 2 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC34665.1 - 3.4e-27 93.4 23.5 1.6e-05 24.3 1.2 7.0 7 0 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat BLOC1_2 PF10046.4 EGC34665.1 - 0.22 11.6 12.9 0.54 10.4 1.4 4.3 3 1 1 4 4 4 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 Oxysterol_BP PF01237.13 EGC34666.1 - 1.1e-65 221.4 6.4 1.9e-65 220.7 4.4 1.3 1 1 0 1 1 1 1 Oxysterol-binding protein FAM60A PF15396.1 EGC34666.1 - 0.035 13.8 1.3 0.067 12.9 0.9 1.3 1 0 0 1 1 1 0 Protein Family FAM60A LRR_1 PF00560.28 EGC34667.1 - 1.2 9.4 7.9 18 5.8 0.0 4.5 3 0 0 3 3 3 0 Leucine Rich Repeat DED PF01335.16 EGC34668.1 - 0.02 14.9 0.5 0.027 14.5 0.4 1.2 1 0 0 1 1 1 0 Death effector domain TcdB_N PF12918.2 EGC34668.1 - 1.7 8.8 9.8 0.56 10.3 0.2 2.3 1 1 1 2 2 2 0 TcdB toxin N-terminal helical domain FlxA PF14282.1 EGC34668.1 - 7.4 6.5 9.5 11 5.9 3.8 2.0 2 0 0 2 2 2 0 FlxA-like protein F-box-like PF12937.2 EGC34669.1 - 2.7e-05 23.7 0.0 6.1e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 F-box-like Ank_2 PF12796.2 EGC34669.1 - 5.5e-05 23.4 0.1 0.00045 20.4 0.0 2.6 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC34669.1 - 0.00034 20.7 0.0 0.00034 20.7 0.0 2.6 2 0 0 2 2 1 1 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC34669.1 - 0.00039 20.8 0.1 0.027 14.9 0.0 2.9 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC34669.1 - 0.0016 18.1 0.1 0.44 10.4 0.0 4.0 4 1 0 4 4 4 1 Ankyrin repeat F-box PF00646.28 EGC34669.1 - 0.0018 17.8 0.1 0.012 15.2 0.0 2.5 2 0 0 2 2 2 1 F-box domain CTD_bind PF04818.8 EGC34669.1 - 0.0022 18.1 2.3 0.005 17.0 0.2 2.8 3 0 0 3 3 2 1 RNA polymerase II-binding domain. Apc15p PF05841.6 EGC34669.1 - 0.0026 18.5 11.4 0.0074 17.0 7.9 1.8 1 0 0 1 1 1 1 Apc15p protein LRR_7 PF13504.1 EGC34669.1 - 0.0029 17.5 2.7 7.6 7.2 0.2 5.1 3 0 0 3 3 3 1 Leucine rich repeat Menin PF05053.8 EGC34669.1 - 1.6 6.8 9.7 19 3.2 8.2 1.6 2 0 0 2 2 2 0 Menin Secretin_N_2 PF07655.8 EGC34669.1 - 4.2 7.8 22.6 14 6.1 15.6 1.9 1 0 0 1 1 1 0 Secretin N-terminal domain SLT PF01464.15 EGC34670.1 - 2e-08 33.7 0.0 3.9e-08 32.8 0.0 1.5 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 EGC34670.1 - 0.0012 18.7 1.4 0.035 14.0 0.9 2.2 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family SOG2 PF10428.4 EGC34670.1 - 4.3 5.8 7.1 4.2 5.9 4.9 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Pex14_N PF04695.8 EGC34671.1 - 0.027 14.5 0.8 0.051 13.6 0.6 1.4 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TFIIIC_delta PF12657.2 EGC34671.1 - 1 9.0 6.7 4.4 6.9 3.1 2.0 1 1 1 2 2 2 0 Transcription factor IIIC subunit delta N-term AMPKBI PF04739.10 EGC34673.1 - 3.2e-20 71.8 1.4 3.2e-20 71.8 1.0 2.8 2 1 0 2 2 2 1 5'-AMP-activated protein kinase beta subunit, interation domain CBM_48 PF02922.13 EGC34673.1 - 0.089 12.8 0.1 0.23 11.5 0.0 1.6 1 0 0 1 1 1 0 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) Med15 PF09606.5 EGC34673.1 - 0.11 10.7 53.9 0.13 10.4 37.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF106 PF01956.11 EGC34673.1 - 0.12 11.9 11.1 0.086 12.3 6.1 1.8 2 0 0 2 2 2 0 Integral membrane protein DUF106 VIT1 PF01988.14 EGC34673.1 - 0.14 11.5 0.5 0.21 11.0 0.3 1.2 1 0 0 1 1 1 0 VIT family PAT1 PF09770.4 EGC34673.1 - 0.8 7.8 40.6 1.2 7.3 28.1 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MCPVI PF02993.9 EGC34673.1 - 3 7.9 15.9 0.13 12.3 6.8 1.7 2 0 0 2 2 2 0 Minor capsid protein VI TFIIA PF03153.8 EGC34673.1 - 10 5.9 29.3 15 5.3 20.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit G-alpha PF00503.15 EGC34674.1 - 7.9e-13 47.8 18.8 7.8e-12 44.5 13.0 2.6 1 1 0 1 1 1 1 G-protein alpha subunit G-gamma PF00631.17 EGC34674.1 - 5.4e-05 22.8 0.1 0.00012 21.7 0.0 1.5 1 0 0 1 1 1 1 GGL domain Trypsin_2 PF13365.1 EGC34675.1 - 1.2e-16 60.7 0.1 2.7e-16 59.6 0.0 1.6 1 0 0 1 1 1 1 Trypsin-like peptidase domain Trypsin PF00089.21 EGC34675.1 - 2.7e-16 59.8 0.0 5.8e-16 58.7 0.0 1.6 1 0 0 1 1 1 1 Trypsin PDZ_2 PF13180.1 EGC34675.1 - 8e-11 41.6 0.1 2.7e-09 36.8 0.0 2.4 2 0 0 2 2 2 1 PDZ domain PDZ PF00595.19 EGC34675.1 - 8.2e-05 22.7 1.5 0.0025 17.9 0.1 2.6 2 0 0 2 2 2 1 PDZ domain (Also known as DHR or GLGF) PDZ_1 PF12812.2 EGC34675.1 - 0.21 11.5 1.2 5.7 6.9 0.0 3.0 3 0 0 3 3 3 0 PDZ-like domain WD40 PF00400.27 EGC34676.1 - 1.4e-11 43.8 22.2 2.1e-06 27.4 0.3 6.3 5 1 0 5 5 5 4 WD domain, G-beta repeat Dynein_IC2 PF11540.3 EGC34676.1 - 2.8e-11 42.5 1.0 7.3e-11 41.2 0.1 2.1 2 0 0 2 2 2 1 Cytoplasmic dynein 1 intermediate chain 2 BolA PF01722.13 EGC34677.1 - 2.7e-29 100.9 0.2 3.8e-29 100.4 0.2 1.2 1 0 0 1 1 1 1 BolA-like protein PI3Ka PF00613.15 EGC34678.1 - 4.4e-16 58.5 1.3 1.1e-14 54.0 0.9 2.4 1 1 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC34678.1 - 9.9e-12 44.8 11.7 3.7e-11 42.9 1.8 3.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FYVE PF01363.16 EGC34678.1 - 1.8e-11 43.7 5.5 1.8e-11 43.7 3.8 1.9 2 0 0 2 2 2 1 FYVE zinc finger Pyr_redox_2 PF07992.9 EGC34679.1 - 7.5e-30 104.3 5.8 5.1e-29 101.6 4.0 2.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC34679.1 - 2.3e-15 56.7 1.3 2.3e-15 56.7 0.9 2.8 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC34679.1 - 4.6e-10 39.8 0.5 4.8e-08 33.3 0.0 2.7 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC34679.1 - 0.0003 19.9 0.5 0.055 12.5 0.0 2.2 2 0 0 2 2 2 2 FAD dependent oxidoreductase K_oxygenase PF13434.1 EGC34679.1 - 0.00033 19.6 0.4 0.012 14.5 0.0 2.5 2 1 1 3 3 3 1 L-lysine 6-monooxygenase (NADPH-requiring) HI0933_like PF03486.9 EGC34679.1 - 0.00037 19.0 1.2 0.49 8.8 0.0 2.4 1 1 0 2 2 2 2 HI0933-like protein NAD_binding_7 PF13241.1 EGC34679.1 - 0.00082 19.5 0.5 0.0054 16.9 0.1 2.2 2 0 0 2 2 2 1 Putative NAD(P)-binding Thi4 PF01946.12 EGC34679.1 - 0.0085 15.2 1.1 0.025 13.6 0.2 2.1 2 0 0 2 2 2 1 Thi4 family FAD_binding_2 PF00890.19 EGC34679.1 - 0.0085 14.9 3.1 0.57 8.9 1.0 2.6 1 1 1 2 2 2 2 FAD binding domain Shikimate_DH PF01488.15 EGC34679.1 - 0.13 12.3 1.3 0.51 10.4 0.1 2.2 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase GIDA PF01134.17 EGC34679.1 - 1.2 7.8 9.7 2.5 6.8 1.5 3.4 2 2 2 4 4 4 0 Glucose inhibited division protein A KH_1 PF00013.24 EGC34680.1 - 0.025 14.1 0.0 0.062 12.9 0.0 1.7 1 0 0 1 1 1 0 KH domain KH_3 PF13014.1 EGC34680.1 - 0.044 13.4 0.0 0.11 12.1 0.0 1.7 1 0 0 1 1 1 0 KH domain VIT1 PF01988.14 EGC34680.1 - 0.69 9.3 1.9 1.2 8.5 1.3 1.3 1 0 0 1 1 1 0 VIT family EMP24_GP25L PF01105.19 EGC34680.1 - 0.8 9.3 4.6 1.4 8.6 3.2 1.4 1 0 0 1 1 1 0 emp24/gp25L/p24 family/GOLD AAA_23 PF13476.1 EGC34680.1 - 2.8 8.1 17.5 0.22 11.8 8.1 2.0 2 0 0 2 2 2 0 AAA domain Peptidase_S10 PF00450.17 EGC34681.1 - 2.9e-100 336.3 7.7 3.5e-100 336.0 5.3 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase Pkinase PF00069.20 EGC34683.1 - 1.8e-56 191.1 0.0 2.6e-56 190.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34683.1 - 9.7e-24 83.8 0.0 1.3e-23 83.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC34683.1 - 2.8e-09 36.3 0.0 4.5e-09 35.6 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Seadorna_VP7 PF07387.6 EGC34683.1 - 0.0011 17.8 0.7 0.0021 16.9 0.0 1.7 2 0 0 2 2 2 1 Seadornavirus VP7 RIO1 PF01163.17 EGC34683.1 - 0.0018 17.6 0.0 0.0039 16.5 0.0 1.5 1 1 0 1 1 1 1 RIO1 family APH PF01636.18 EGC34683.1 - 0.035 13.8 0.0 0.053 13.2 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Coiled PF05710.7 EGC34685.1 - 0.082 13.3 8.7 0.1 13.0 6.0 1.1 1 0 0 1 1 1 0 Coiled coil Gly-zipper_OmpA PF13436.1 EGC34685.1 - 0.14 11.8 3.3 0.22 11.1 2.3 1.4 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Coiled PF05710.7 EGC34686.1 - 9.5e-13 48.4 26.2 1.1e-12 48.2 18.1 1.0 1 0 0 1 1 1 1 Coiled coil CitMHS PF03600.11 EGC34686.1 - 0.088 11.3 0.6 0.093 11.2 0.4 1.0 1 0 0 1 1 1 0 Citrate transporter Coiled PF05710.7 EGC34687.1 - 4.4e-17 62.3 29.4 5.1e-17 62.1 20.4 1.0 1 0 0 1 1 1 1 Coiled coil FNIP PF05725.7 EGC34688.1 - 5.6e-47 157.4 81.9 4.8e-12 45.6 3.0 11.7 9 2 2 11 11 11 10 FNIP Repeat Collagen PF01391.13 EGC34691.1 - 0.079 12.5 2.1 0.12 11.9 1.5 1.1 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Mon1 PF03164.9 EGC34692.1 - 1.1e-106 356.8 15.8 1.4e-106 356.6 10.9 1.0 1 0 0 1 1 1 1 Trafficking protein Mon1 Mating_N PF12731.2 EGC34692.1 - 0.045 13.6 2.0 5.7 6.8 0.0 3.2 3 0 0 3 3 3 0 Mating-type protein beta 1 zf-Tim10_DDP PF02953.10 EGC34693.1 - 0.78 9.0 5.3 0.32 10.2 2.1 1.6 1 1 1 2 2 2 0 Tim10/DDP family zinc finger THDPS_N PF14790.1 EGC34694.1 - 0.13 11.8 0.0 0.15 11.7 0.0 1.1 1 0 0 1 1 1 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal ALG3 PF05208.8 EGC34695.1 - 3.4e-54 184.4 35.7 1.4e-53 182.4 25.3 1.5 2 0 0 2 2 2 1 ALG3 protein DUF1295 PF06966.7 EGC34696.1 - 2.5e-43 148.0 2.3 3e-43 147.8 1.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) ICMT PF04140.9 EGC34696.1 - 8.3e-05 22.7 1.7 0.0001 22.4 0.2 1.9 2 0 0 2 2 2 1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family DUF2701 PF10857.3 EGC34696.1 - 0.09 12.5 1.9 0.54 10.0 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2701) U-box PF04564.10 EGC34697.1 - 1.7e-18 66.3 0.1 8.4e-18 64.1 0.1 2.3 1 0 0 1 1 1 1 U-box domain zf-Nse PF11789.3 EGC34697.1 - 0.0051 16.3 0.0 0.019 14.4 0.0 2.0 1 0 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit DUF3439 PF11921.3 EGC34697.1 - 0.02 14.6 2.2 0.28 10.9 2.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Rtf2 PF04641.7 EGC34697.1 - 0.72 9.0 0.0 0.72 9.0 0.0 4.3 1 1 2 3 3 3 0 Rtf2 RING-finger Neur_chan_memb PF02932.11 EGC34697.1 - 2.1 8.1 17.6 0.97 9.2 6.7 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Vps35 PF03635.12 EGC34698.1 - 3.7e-262 871.9 19.3 4.2e-262 871.7 13.3 1.0 1 0 0 1 1 1 1 Vacuolar protein sorting-associated protein 35 Imm46 PF15585.1 EGC34698.1 - 0.0095 15.9 0.5 14 5.7 0.0 4.0 4 0 0 4 4 4 2 Immunity protein 46 DnaG_DnaB_bind PF08278.6 EGC34698.1 - 0.022 15.0 0.3 16 5.7 0.0 4.2 4 0 0 4 4 4 0 DNA primase DnaG DnaB-binding Peptidase_S10 PF00450.17 EGC34699.1 - 7.8e-68 229.5 10.1 2.1e-36 125.9 0.2 2.0 1 1 1 2 2 2 2 Serine carboxypeptidase EGF_2 PF07974.8 EGC34701.1 - 0.7 10.1 15.8 0.055 13.6 7.5 1.7 2 0 0 2 2 2 0 EGF-like domain EGF_2 PF07974.8 EGC34702.1 - 0.0067 16.5 9.6 0.0067 16.5 6.7 1.8 2 0 0 2 2 2 1 EGF-like domain EGF_2 PF07974.8 EGC34703.1 - 0.019 15.0 11.1 0.019 15.0 7.7 1.9 2 0 0 2 2 2 0 EGF-like domain Amnionless PF14828.1 EGC34703.1 - 0.052 12.0 0.0 0.052 12.0 0.0 1.7 2 0 0 2 2 2 0 Amnionless EGF_2 PF07974.8 EGC34704.1 - 9.4e-05 22.4 10.5 9.4e-05 22.4 7.3 3.2 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.19 EGC34704.1 - 0.0054 16.6 25.4 0.041 13.8 5.7 3.1 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) PMP1_2 PF08114.6 EGC34704.1 - 2.8 7.5 4.9 0.66 9.5 0.6 2.0 2 0 0 2 2 2 0 ATPase proteolipid family hEGF PF12661.2 EGC34704.1 - 4.5 7.5 8.0 0.65 10.1 0.8 3.1 2 0 0 2 2 2 0 Human growth factor-like EGF Acyl-CoA_dh_1 PF00441.19 EGC34705.1 - 6.1e-43 146.5 0.4 1e-42 145.7 0.0 1.6 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGC34705.1 - 2.6e-36 124.6 0.0 4.8e-36 123.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGC34705.1 - 1.2e-20 72.6 0.1 2.7e-20 71.6 0.1 1.6 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGC34705.1 - 2.5e-13 50.4 0.0 1.8e-12 47.6 0.0 2.0 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, C-terminal domain HpaB_N PF11794.3 EGC34705.1 - 0.0092 15.4 0.1 0.059 12.7 0.1 2.1 1 1 0 1 1 1 1 4-hydroxyphenylacetate 3-hydroxylase N terminal Dopey_N PF04118.9 EGC34706.1 - 9.9e-99 329.9 7.0 9.9e-99 329.9 4.8 4.9 5 1 1 6 6 6 1 Dopey, N-terminal DUF3430 PF11912.3 EGC34708.1 - 1.7e-18 67.2 35.7 1.9e-18 67.0 24.8 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) WD40 PF00400.27 EGC34710.1 - 3e-74 242.4 23.2 2.6e-09 36.6 0.1 10.6 10 0 0 10 10 10 9 WD domain, G-beta repeat Utp13 PF08625.6 EGC34710.1 - 4.9e-39 133.1 0.3 4.9e-39 133.1 0.2 1.7 2 0 0 2 2 2 1 Utp13 specific WD40 associated domain Nup160 PF11715.3 EGC34710.1 - 1.7e-09 36.4 10.4 0.059 11.5 0.1 6.6 2 2 3 6 6 6 4 Nucleoporin Nup120/160 Str_synth PF03088.11 EGC34710.1 - 0.00047 20.1 0.0 2.6 8.1 0.0 3.3 2 0 0 2 2 2 2 Strictosidine synthase BBS2_Mid PF14783.1 EGC34710.1 - 0.0084 15.8 1.7 15 5.4 0.1 5.1 3 1 2 5 5 5 1 Ciliary BBSome complex subunit 2, middle region HPS3_N PF14761.1 EGC34710.1 - 0.027 13.8 0.3 0.3 10.4 0.0 2.9 2 2 3 5 5 5 0 Hermansky-Pudlak syndrome 3 TIG PF01833.19 EGC34711.1 - 2.9e-20 72.0 76.6 7.3e-06 25.8 1.7 8.6 8 0 0 8 8 8 7 IPT/TIG domain EGF_2 PF07974.8 EGC34711.1 - 0.021 14.9 12.1 0.051 13.7 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 EGC34711.1 - 0.093 12.6 8.1 0.22 11.4 5.6 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EGC34711.1 - 0.72 9.8 8.9 1.9 8.5 6.2 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 EGC34712.1 - 3.4e-90 296.1 152.9 2.6e-12 46.5 0.4 18.8 18 1 1 19 19 19 12 IPT/TIG domain DUF3834 PF12916.2 EGC34713.1 - 0.011 14.7 0.1 0.013 14.5 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3834) DUF1631 PF07793.6 EGC34713.1 - 0.019 13.1 0.2 0.023 12.8 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1631) Med2 PF11214.3 EGC34713.1 - 0.024 14.6 1.2 0.026 14.5 0.8 1.1 1 0 0 1 1 1 0 Mediator complex subunit 2 Xpo1 PF08389.7 EGC34713.1 - 0.048 13.5 1.6 0.059 13.2 1.1 1.1 1 0 0 1 1 1 0 Exportin 1-like protein Rota_NSP4 PF01452.11 EGC34713.1 - 0.071 12.4 1.2 0.076 12.3 0.8 1.2 1 0 0 1 1 1 0 Rotavirus non structural protein dTMP_synthase PF02593.9 EGC34713.1 - 0.077 12.3 0.4 0.091 12.0 0.3 1.0 1 0 0 1 1 1 0 Thymidylate synthase TMF_DNA_bd PF12329.3 EGC34713.1 - 0.11 12.3 4.6 0.15 11.8 3.2 1.2 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding Peptidase_C6 PF00851.13 EGC34713.1 - 0.13 10.8 1.0 0.13 10.8 0.7 1.1 1 0 0 1 1 1 0 Helper component proteinase DUF572 PF04502.8 EGC34715.1 - 0.1 11.7 30.7 0.059 12.5 16.8 2.1 2 0 0 2 2 2 0 Family of unknown function (DUF572) Tim17 PF02466.14 EGC34716.1 - 0.0036 17.3 4.9 0.33 10.9 0.0 2.4 2 0 0 2 2 2 2 Tim17/Tim22/Tim23/Pmp24 family Rhomboid PF01694.17 EGC34716.1 - 0.021 14.8 0.3 0.035 14.1 0.2 1.4 1 0 0 1 1 1 0 Rhomboid family DUF533 PF04391.7 EGC34716.1 - 0.03 13.6 0.7 0.042 13.2 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF533) TatD_DNase PF01026.16 EGC34716.1 - 0.034 13.3 0.0 0.048 12.8 0.0 1.1 1 0 0 1 1 1 0 TatD related DNase Romo1 PF10247.4 EGC34716.1 - 0.34 11.1 6.2 0.13 12.4 0.5 2.5 3 0 0 3 3 3 0 Reactive mitochondrial oxygen species modulator 1 RTC PF01137.16 EGC34717.1 - 1.4e-75 253.0 0.2 1.7e-75 252.7 0.1 1.1 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase RTC_insert PF05189.8 EGC34717.1 - 9.6e-19 67.3 0.0 1.7e-18 66.5 0.0 1.4 1 0 0 1 1 1 1 RNA 3'-terminal phosphate cyclase (RTC), insert domain Menin PF05053.8 EGC34717.1 - 0.055 11.6 3.8 0.075 11.1 2.6 1.2 1 0 0 1 1 1 0 Menin Dicty_REP PF05086.7 EGC34717.1 - 0.19 9.4 12.1 0.28 8.8 8.4 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Guanylate_cyc PF00211.15 EGC34718.1 - 4.8e-26 91.2 0.0 1.2e-13 50.8 0.0 2.6 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain TPR_11 PF13414.1 EGC34718.1 - 0.00048 19.7 3.6 3.8 7.2 0.0 4.4 4 0 0 4 4 4 2 TPR repeat TPR_12 PF13424.1 EGC34718.1 - 0.00048 19.9 0.6 5.6 6.9 0.0 4.4 4 1 0 4 4 4 1 Tetratricopeptide repeat AAA_16 PF13191.1 EGC34718.1 - 0.0014 18.6 1.2 0.014 15.4 0.0 3.0 3 1 0 3 3 3 1 AAA ATPase domain TPR_2 PF07719.12 EGC34718.1 - 0.0064 16.3 6.5 9.4 6.4 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC34718.1 - 0.14 12.3 4.6 0.37 10.9 0.2 3.5 3 1 1 4 4 4 0 Anaphase-promoting complex, cyclosome, subunit 3 NUDIX PF00293.23 EGC34719.1 - 4e-15 55.6 0.0 7.1e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Telomere_Sde2 PF13019.1 EGC34720.1 - 1.3e-26 93.2 3.3 1.3e-26 93.2 2.3 2.4 2 1 1 3 3 3 1 Telomere stability and silencing DUF3439 PF11921.3 EGC34720.1 - 0.03 14.0 1.4 0.056 13.1 1.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) BSP_II PF05432.6 EGC34720.1 - 0.15 11.3 15.5 0.23 10.6 10.7 1.3 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) DUF3474 PF11960.3 EGC34720.1 - 1.4 8.9 6.1 3 7.8 4.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3474) FLO_LFY PF01698.11 EGC34720.1 - 4.2 6.1 13.3 5.3 5.7 9.2 1.3 1 0 0 1 1 1 0 Floricaula / Leafy protein DNA_pol_A PF00476.15 EGC34721.1 - 2.8e-62 210.5 0.2 1.2e-54 185.3 0.1 2.1 2 0 0 2 2 2 2 DNA polymerase family A Mito_fiss_reg PF05308.6 EGC34722.1 - 2.3 7.4 7.2 0.28 10.5 2.0 1.5 1 1 0 2 2 2 0 Mitochondrial fission regulator SpoU_methylase PF00588.14 EGC34723.1 - 2.1e-24 85.9 0.0 5.2e-24 84.7 0.0 1.7 1 0 0 1 1 1 1 SpoU rRNA Methylase family TAF8_C PF10406.4 EGC34725.1 - 5e-17 61.6 0.6 5e-17 61.6 0.4 2.5 2 1 1 3 3 3 1 Transcription factor TFIID complex subunit 8 C-term Bromo_TP PF07524.8 EGC34725.1 - 5.8e-15 54.7 0.1 1e-14 54.0 0.1 1.4 1 0 0 1 1 1 1 Bromodomain associated Trm112p PF03966.11 EGC34726.1 - 4.3e-13 49.4 0.1 6.5e-13 48.8 0.1 1.3 1 0 0 1 1 1 1 Trm112p-like protein zinc_ribbon_4 PF13717.1 EGC34726.1 - 0.031 13.9 0.2 0.13 11.9 0.1 2.1 1 0 0 1 1 1 0 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGC34726.1 - 0.037 13.6 0.1 0.13 11.8 0.1 2.0 1 0 0 1 1 1 0 zinc-ribbon domain Integrase_Zn PF02022.14 EGC34726.1 - 1.3 8.4 3.6 28 4.2 0.0 3.2 3 0 0 3 3 3 0 Integrase Zinc binding domain SRF-TF PF00319.13 EGC34727.1 - 1e-23 82.2 0.1 1.8e-23 81.5 0.0 1.4 1 0 0 1 1 1 1 SRF-type transcription factor (DNA-binding and dimerisation domain) Ilar_coat PF01787.11 EGC34727.1 - 2.2 7.8 13.4 3.9 6.9 9.3 1.3 1 0 0 1 1 1 0 Ilarvirus coat protein ALMT PF11744.3 EGC34727.1 - 2.4 6.7 4.4 3 6.4 3.1 1.2 1 0 0 1 1 1 0 Aluminium activated malate transporter Neur_chan_memb PF02932.11 EGC34727.1 - 3.7 7.3 15.7 0.45 10.3 7.8 1.7 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Erf4 PF10256.4 EGC34728.1 - 1.5e-21 76.3 0.5 3e-11 43.2 0.0 2.2 1 1 1 2 2 2 2 Golgin subfamily A member 7/ERF4 family Ion_trans_N PF08412.5 EGC34728.1 - 0.21 10.9 1.3 0.45 9.8 0.9 1.5 1 0 0 1 1 1 0 Ion transport protein N-terminal BRCT PF00533.21 EGC34729.1 - 0.00052 20.1 2.3 0.0029 17.7 0.1 3.1 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain tRNA-synt_2 PF00152.15 EGC34730.1 - 7.1e-89 297.8 0.1 1e-88 297.3 0.1 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGC34730.1 - 2.6e-12 46.4 0.1 5.3e-12 45.4 0.0 1.6 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGC34730.1 - 4e-07 29.4 0.0 0.0018 17.5 0.0 2.4 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGC34730.1 - 0.057 12.9 0.3 5.1 6.6 0.0 2.7 2 0 0 2 2 2 0 tRNA synthetase class II core domain (G, H, P, S and T) TTL PF03133.10 EGC34731.1 - 1.2e-59 201.6 8.6 1.2e-59 201.6 5.9 2.1 2 1 0 2 2 2 1 Tubulin-tyrosine ligase family ATPgrasp_YheCD PF14398.1 EGC34731.1 - 0.00027 19.8 6.1 0.0025 16.6 0.2 2.8 3 0 0 3 3 3 2 YheC/D like ATP-grasp Dala_Dala_lig_C PF07478.8 EGC34731.1 - 0.0011 18.4 0.1 0.85 8.9 0.0 2.9 2 1 1 3 3 3 2 D-ala D-ala ligase C-terminus RimK PF08443.6 EGC34731.1 - 0.0016 17.9 0.4 0.14 11.6 0.0 2.5 2 0 0 2 2 2 1 RimK-like ATP-grasp domain CP_ATPgrasp_1 PF04174.8 EGC34731.1 - 0.034 12.7 0.0 0.31 9.6 0.0 2.2 2 0 0 2 2 2 0 A circularly permuted ATPgrasp ATP-grasp_3 PF02655.9 EGC34731.1 - 0.051 13.4 0.0 3.2 7.5 0.0 2.5 2 1 0 2 2 2 0 ATP-grasp domain ATP-grasp_4 PF13535.1 EGC34731.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 ATP-grasp domain Vinculin PF01044.14 EGC34732.1 - 9.9e-16 56.9 129.9 4.1e-11 41.6 24.6 6.2 1 1 0 2 2 2 2 Vinculin family Cloacin_immun PF03513.9 EGC34732.1 - 0.001 19.0 0.1 0.0043 17.0 0.1 2.1 1 0 0 1 1 1 1 Cloacin immunity protein DUF434 PF04256.7 EGC34732.1 - 0.011 15.0 0.0 0.046 13.0 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF434) SNF2_N PF00176.18 EGC34733.1 - 2e-68 230.3 0.3 1.2e-67 227.8 0.0 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC34733.1 - 8.1e-14 51.2 0.1 4.4e-13 48.9 0.0 2.4 3 0 0 3 3 3 1 Helicase conserved C-terminal domain CBM49 PF09478.5 EGC34734.1 - 3.6e-05 23.7 2.6 5.2e-05 23.2 1.8 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Ras PF00071.17 EGC34736.1 - 5.4e-37 126.6 0.5 6.8e-37 126.3 0.4 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34736.1 - 1.8e-11 44.5 0.0 3.1e-11 43.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein AAA_14 PF13173.1 EGC34736.1 - 0.011 15.6 0.3 0.027 14.3 0.2 1.9 1 1 0 1 1 1 0 AAA domain Exo_endo_phos PF03372.18 EGC34737.1 - 9.8e-32 110.8 0.0 1.4e-31 110.3 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RhoGAP PF00620.22 EGC34737.1 - 4.8e-29 100.9 0.1 1e-28 99.8 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Ndc1_Nup PF09531.5 EGC34737.1 - 0.019 13.4 2.8 0.029 12.8 1.9 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PAP_assoc PF03828.14 EGC34739.1 - 4.8e-10 39.2 0.4 1.3e-09 37.8 0.3 1.8 1 0 0 1 1 1 1 Cid1 family poly A polymerase Carbpep_Y_N PF05388.6 EGC34740.1 - 0.0013 18.9 2.1 0.023 14.8 0.1 2.4 2 1 0 2 2 2 1 Carboxypeptidase Y pro-peptide SNARE PF05739.14 EGC34740.1 - 0.0054 16.4 1.5 0.0083 15.7 0.1 2.0 2 0 0 2 2 2 1 SNARE domain BAR PF03114.13 EGC34740.1 - 0.0099 15.4 4.6 0.019 14.4 3.2 1.4 1 0 0 1 1 1 1 BAR domain DUF4200 PF13863.1 EGC34740.1 - 0.013 15.4 5.0 0.025 14.5 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Flu_NS2 PF00601.14 EGC34740.1 - 0.022 14.9 1.4 0.038 14.1 0.2 2.0 2 0 0 2 2 2 0 Influenza non-structural protein (NS2) FlxA PF14282.1 EGC34740.1 - 0.041 13.8 0.6 0.11 12.3 0.4 1.7 1 0 0 1 1 1 0 FlxA-like protein TetR_C_8 PF14278.1 EGC34740.1 - 0.046 14.0 0.2 0.046 14.0 0.1 2.0 2 0 0 2 2 2 0 Transcriptional regulator C-terminal region Sec2p PF06428.6 EGC34740.1 - 0.059 13.2 2.8 0.12 12.2 2.0 1.5 1 0 0 1 1 1 0 GDP/GTP exchange factor Sec2p Microtub_assoc PF07989.6 EGC34740.1 - 0.088 12.6 3.8 0.13 12.1 0.9 2.5 2 0 0 2 2 2 0 Microtubule associated MbeD_MobD PF04899.7 EGC34740.1 - 0.096 12.5 0.6 0.24 11.3 0.2 1.7 2 0 0 2 2 2 0 MbeD/MobD like LUC7 PF03194.10 EGC34740.1 - 0.23 10.9 2.9 0.4 10.1 2.0 1.3 1 0 0 1 1 1 0 LUC7 N_terminus Tbf5 PF06331.7 EGC34740.1 - 0.61 9.8 3.9 0.46 10.3 0.8 2.2 2 1 0 2 2 2 0 Transcription factor TFIIH complex subunit Tfb5 Cnl2_NKP2 PF09447.5 EGC34741.1 - 0.036 13.7 0.0 0.08 12.6 0.0 1.5 2 0 0 2 2 2 0 Cnl2/NKP2 family protein Peptidase_M15 PF01427.12 EGC34741.1 - 0.079 12.5 0.0 0.082 12.5 0.0 1.1 1 0 0 1 1 1 0 D-ala-D-ala dipeptidase DUF3919 PF13057.1 EGC34741.1 - 0.093 12.1 2.3 0.16 11.4 0.1 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3919) FA_hydroxylase PF04116.8 EGC34743.1 - 2.4e-11 44.0 27.0 2.4e-11 44.0 18.7 2.8 3 0 0 3 3 3 1 Fatty acid hydroxylase superfamily DUF2971 PF11185.3 EGC34743.1 - 1.9 9.2 6.8 37 5.1 0.0 3.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2971) FNIP PF05725.7 EGC34744.1 - 5.1e-16 58.3 36.4 2.6e-05 24.0 3.2 6.4 3 1 3 7 7 7 6 FNIP Repeat zf-B_box PF00643.19 EGC34744.1 - 7.3e-07 28.9 5.1 1.3e-06 28.1 3.6 1.4 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC34744.1 - 0.073 12.8 2.7 0.15 11.7 1.9 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) DUF2523 PF10734.4 EGC34744.1 - 0.095 12.9 0.1 50 4.2 0.0 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF2523) E6 PF00518.12 EGC34744.1 - 0.4 11.0 3.1 0.51 10.6 1.1 1.9 2 0 0 2 2 2 0 Early Protein (E6) DUF1644 PF07800.7 EGC34744.1 - 1.1 9.1 7.3 0.52 10.1 3.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1644) Glyco_hydro_9 PF00759.14 EGC34746.1 - 2.8e-122 408.8 22.0 3.3e-122 408.5 15.2 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 TIR-like PF10137.4 EGC34747.1 - 1.6e-33 114.9 0.9 1.9e-33 114.7 0.0 1.5 2 0 0 2 2 2 1 Predicted nucleotide-binding protein containing TIR-like domain TIR_2 PF13676.1 EGC34747.1 - 6.9e-05 22.9 0.0 8.8e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 TIR domain V_ATPase_I PF01496.14 EGC34747.1 - 0.0076 14.1 0.6 0.01 13.7 0.4 1.2 1 0 0 1 1 1 1 V-type ATPase 116kDa subunit family DUF4062 PF13271.1 EGC34747.1 - 0.021 14.8 0.0 0.038 14.0 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4062) TIR PF01582.15 EGC34747.1 - 0.034 13.5 0.1 0.058 12.8 0.0 1.4 1 0 0 1 1 1 0 TIR domain SpoIIP PF07454.6 EGC34747.1 - 0.18 10.9 12.1 0.27 10.3 8.4 1.2 1 0 0 1 1 1 0 Stage II sporulation protein P (SpoIIP) TT_ORF1 PF02956.9 EGC34747.1 - 9.4 4.5 11.5 13 4.1 8.0 1.2 1 0 0 1 1 1 0 TT viral orf 1 HSP20 PF00011.16 EGC34748.1 - 1.3e-14 53.8 1.6 3.1e-06 26.9 0.0 2.3 2 0 0 2 2 2 2 Hsp20/alpha crystallin family AUX_IAA PF02309.11 EGC34748.1 - 0.079 12.6 2.9 0.11 12.1 2.0 1.3 1 0 0 1 1 1 0 AUX/IAA family Utp12 PF04003.7 EGC34749.1 - 1.7e-14 53.6 1.3 2.8e-14 52.9 0.5 1.7 2 0 0 2 2 2 1 Dip2/Utp12 Family WD40 PF00400.27 EGC34749.1 - 0.026 14.4 0.0 1.3 9.0 0.0 3.3 3 0 0 3 3 3 0 WD domain, G-beta repeat PQQ_2 PF13360.1 EGC34749.1 - 0.066 12.6 0.0 0.48 9.8 0.0 2.2 1 1 0 1 1 1 0 PQQ-like domain TT_ORF2 PF02957.10 EGC34749.1 - 2.1 9.0 5.9 4.4 8.0 4.1 1.6 1 0 0 1 1 1 0 TT viral ORF2 Myb_DNA-binding PF00249.26 EGC34750.1 - 3.2e-31 107.1 13.1 9.7e-13 47.9 0.1 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC34750.1 - 2.6e-28 97.8 18.4 1.6e-11 44.0 0.0 3.8 4 0 0 4 4 4 3 Myb-like DNA-binding domain Neur_chan_memb PF02932.11 EGC34750.1 - 0.081 12.8 4.0 0.11 12.3 2.8 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region MADF_DNA_bdg PF10545.4 EGC34750.1 - 0.083 13.0 9.7 2 8.6 0.1 4.0 4 0 0 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Rap1_C PF11626.3 EGC34750.1 - 0.12 12.2 6.2 17 5.3 2.7 3.2 1 1 1 2 2 2 0 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EGC34750.1 - 0.19 11.5 1.2 15 5.5 0.0 3.4 3 1 0 3 3 3 0 Rap1 Myb domain MFS_1 PF07690.11 EGC34751.1 - 1.4e-24 86.4 25.9 4.1e-22 78.3 11.2 2.7 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGC34751.1 - 3.8e-17 61.8 6.0 3.8e-17 61.8 4.1 2.6 2 0 0 2 2 2 1 MFS_1 like family Nuc_H_symport PF03825.11 EGC34751.1 - 3.8e-14 52.2 6.4 3.8e-14 52.2 4.4 2.3 2 1 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.14 EGC34751.1 - 0.00091 17.8 14.8 0.00091 17.8 10.3 2.1 2 0 0 2 2 2 2 LacY proton/sugar symporter RIC3 PF15361.1 EGC34751.1 - 0.11 12.6 1.8 0.2 11.8 1.2 1.3 1 0 0 1 1 1 0 Resistance to inhibitors of cholinesterase homologue 3 Glycos_trans_3N PF02885.12 EGC34751.1 - 0.16 11.5 0.0 0.34 10.5 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain SecG PF03840.9 EGC34751.1 - 0.23 11.2 0.0 0.23 11.2 0.0 3.3 3 0 0 3 3 3 0 Preprotein translocase SecG subunit AAA_22 PF13401.1 EGC34752.1 - 0.00011 22.3 0.0 0.87 9.7 0.0 5.0 5 0 0 5 5 5 2 AAA domain AAA PF00004.24 EGC34752.1 - 0.00026 21.1 1.7 0.026 14.7 0.0 4.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGC34752.1 - 0.97 8.7 0.0 2.6 7.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF3439 PF11921.3 EGC34752.1 - 2.8 7.6 9.6 8.5 6.1 6.6 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) AAA_16 PF13191.1 EGC34752.1 - 4 7.3 7.8 10 6.0 0.0 4.2 4 1 0 4 4 4 0 AAA ATPase domain Sulfate_tra_GLY PF13792.1 EGC34752.1 - 4.6 6.9 0.4 10 5.8 0.3 1.5 1 0 0 1 1 1 0 Sulfate transporter N-terminal domain with GLY motif TIG PF01833.19 EGC34753.1 - 0.00038 20.3 0.7 0.00057 19.8 0.5 1.3 1 0 0 1 1 1 1 IPT/TIG domain DUF761 PF05553.6 EGC34754.1 - 0.14 11.5 0.2 0.23 10.8 0.1 1.4 1 0 0 1 1 1 0 Cotton fibre expressed protein DUF4517 PF15006.1 EGC34754.1 - 0.15 11.9 0.6 0.5 10.2 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4517) AP4E_app_platf PF14807.1 EGC34755.1 - 0.018 15.2 0.1 0.051 13.8 0.1 1.8 2 0 0 2 2 2 0 Adaptin AP4 complex epsilon appendage platform Orthopox_A47 PF06334.6 EGC34755.1 - 0.027 13.5 6.8 0.051 12.6 4.7 1.6 1 1 0 1 1 1 0 Orthopoxvirus A47 protein SLAC1 PF03595.12 EGC34756.1 - 0.67 8.5 4.4 0.81 8.2 1.4 2.2 2 1 0 2 2 2 0 Voltage-dependent anion channel RRM_1 PF00076.17 EGC34757.1 - 1.8e-26 91.5 7.7 5e-16 58.0 0.2 3.7 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34757.1 - 1.3e-23 82.7 2.7 1.3e-12 47.4 0.0 3.0 2 1 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34757.1 - 5.4e-14 51.7 2.8 8.2e-08 31.9 0.1 3.2 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC34757.1 - 0.15 11.8 0.0 0.15 11.8 0.0 3.2 3 1 0 3 3 3 0 Limkain b1 FNIP PF05725.7 EGC34758.1 - 3.6e-68 225.2 44.6 1.7e-13 50.2 0.2 8.9 4 2 6 11 11 11 10 FNIP Repeat Enolase_C PF00113.17 EGC34759.1 - 0.028 13.4 0.1 0.033 13.1 0.1 1.0 1 0 0 1 1 1 0 Enolase, C-terminal TIM barrel domain DSPc PF00782.15 EGC34760.1 - 1.4e-24 86.2 0.2 1.5e-23 82.8 0.0 2.1 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC34760.1 - 0.00024 20.5 0.6 0.00089 18.6 0.0 1.9 2 0 0 2 2 2 1 Protein-tyrosine phosphatase Init_tRNA_PT PF04179.7 EGC34760.1 - 0.012 14.4 0.4 0.032 13.1 0.0 1.7 1 1 1 2 2 2 0 Initiator tRNA phosphoribosyl transferase PTPlike_phytase PF14566.1 EGC34760.1 - 0.04 13.9 0.3 1.7 8.7 0.0 2.2 2 0 0 2 2 2 0 Inositol hexakisphosphate HCaRG PF07258.9 EGC34760.1 - 0.042 13.3 0.6 0.081 12.4 0.4 1.5 1 1 0 1 1 1 0 HCaRG protein Y_phosphatase3 PF13350.1 EGC34760.1 - 0.049 13.8 0.4 0.46 10.7 0.0 2.5 2 1 1 3 3 3 0 Tyrosine phosphatase family TACC PF05010.9 EGC34760.1 - 0.065 12.9 0.5 0.1 12.3 0.3 1.3 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) LRR_4 PF12799.2 EGC34761.1 - 1.6e-28 97.7 54.1 6.8e-08 31.9 5.5 6.5 3 2 4 7 7 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC34761.1 - 6.3e-19 67.4 42.6 3.6e-08 33.0 4.6 4.5 4 0 0 4 4 4 4 Leucine rich repeat LRR_9 PF14580.1 EGC34761.1 - 2.7e-10 40.0 19.9 4.1e-05 23.2 2.8 3.3 2 1 1 3 3 3 3 Leucine-rich repeat LRR_1 PF00560.28 EGC34761.1 - 2.2e-09 36.0 35.6 0.55 10.4 0.4 9.9 10 0 0 10 10 10 5 Leucine Rich Repeat LRR_7 PF13504.1 EGC34761.1 - 3e-05 23.5 24.4 0.56 10.6 0.0 8.8 9 0 0 9 9 9 3 Leucine rich repeat LRR_6 PF13516.1 EGC34761.1 - 0.0079 16.1 38.4 0.77 10.0 0.2 9.3 5 3 4 9 9 9 3 Leucine Rich repeat DNase_II PF03265.10 EGC34762.1 - 0.00019 20.5 7.4 0.38 9.6 2.1 3.4 2 1 0 2 2 2 2 Deoxyribonuclease II Cation_ATPase_C PF00689.16 EGC34763.1 - 1.6e-09 37.5 16.2 1.6e-09 37.5 11.3 3.5 4 1 1 5 5 5 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC34763.1 - 3.7e-05 24.2 0.0 0.00012 22.5 0.0 1.9 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase VIT1 PF01988.14 EGC34763.1 - 0.0075 15.7 0.0 0.0075 15.7 0.0 3.5 4 0 0 4 4 4 1 VIT family FPL PF09758.4 EGC34764.1 - 4e-57 192.1 15.3 4e-57 192.1 10.6 2.7 2 0 0 2 2 2 1 Uncharacterised conserved protein Mtp PF03821.11 EGC34764.1 - 0.39 10.0 9.6 0.71 9.2 0.5 2.4 1 1 1 2 2 2 0 Golgi 4-transmembrane spanning transporter SET PF00856.23 EGC34766.1 - 1.1e-09 38.8 11.5 2.4e-08 34.4 7.9 2.5 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGC34766.1 - 1e-05 25.2 9.8 1e-05 25.2 6.8 2.5 2 1 0 2 2 2 1 MYND finger SAF PF08666.7 EGC34766.1 - 0.025 14.9 0.0 1.1 9.7 0.0 2.3 2 0 0 2 2 2 0 SAF domain 7tm_2 PF00002.19 EGC34767.1 - 0.00052 19.1 12.5 0.0023 17.0 8.7 1.9 1 1 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGC34767.1 - 0.0035 16.2 15.7 0.018 13.9 10.9 1.9 1 1 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_1 PF00001.16 EGC34767.1 - 0.0059 15.7 13.0 0.31 10.1 8.5 2.9 1 1 0 1 1 1 1 7 transmembrane receptor (rhodopsin family) DUF3357 PF11837.3 EGC34769.1 - 0.0064 16.3 0.9 0.14 12.0 0.1 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF3357) PS_Dcarbxylase PF02666.10 EGC34769.1 - 0.024 13.9 1.4 0.39 9.9 0.0 2.2 2 0 0 2 2 2 0 Phosphatidylserine decarboxylase OppC_N PF12911.2 EGC34769.1 - 0.035 13.4 0.1 2.5 7.5 0.1 2.6 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Shisa PF13908.1 EGC34769.1 - 0.12 12.5 0.1 1.1 9.4 0.0 2.0 1 1 0 2 2 2 0 Wnt and FGF inhibitory regulator MscS_TM PF12794.2 EGC34769.1 - 0.12 10.9 3.5 0.58 8.7 0.3 2.0 1 1 1 2 2 2 0 Mechanosensitive ion channel inner membrane domain 1 DUF3328 PF11807.3 EGC34769.1 - 0.22 11.1 7.4 2 8.0 0.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3328) AA_permease_2 PF13520.1 EGC34769.1 - 0.39 9.1 11.5 0.26 9.7 3.8 2.0 1 1 1 2 2 2 0 Amino acid permease DUF975 PF06161.6 EGC34769.1 - 0.53 9.9 6.4 0.9 9.2 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF975) Polysacc_synt_3 PF13440.1 EGC34769.1 - 0.57 9.5 7.0 0.61 9.4 0.6 2.0 1 1 1 2 2 2 0 Polysaccharide biosynthesis protein LRRNT_2 PF08263.7 EGC34769.1 - 1 9.3 7.2 8.1 6.4 0.3 3.3 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain DUF202 PF02656.10 EGC34769.1 - 1.1 9.5 9.8 4.8 7.4 1.9 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF202) GST_N PF02798.15 EGC34770.1 - 1.6e-08 34.5 0.1 4.2e-08 33.2 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC34770.1 - 7.5e-08 32.2 0.0 1.3e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC34770.1 - 0.00025 21.1 0.0 0.00044 20.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Apis_Csd PF11671.3 EGC34770.1 - 2.6 7.8 8.4 1.1 8.9 4.1 1.7 2 0 0 2 2 2 0 Complementary sex determiner protein FGGY_N PF00370.16 EGC34771.1 - 1.5e-69 234.0 0.3 2.5e-69 233.3 0.2 1.4 1 0 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EGC34771.1 - 1.2e-61 207.8 2.2 1.9e-61 207.1 0.3 2.0 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain BcrAD_BadFG PF01869.15 EGC34771.1 - 0.1 11.8 0.0 1.2 8.4 0.0 2.1 2 0 0 2 2 2 0 BadF/BadG/BcrA/BcrD ATPase family PH_3 PF14593.1 EGC34772.1 - 6.9e-20 70.8 0.0 1.3e-19 70.0 0.0 1.4 1 0 0 1 1 1 1 PH domain PH PF00169.24 EGC34772.1 - 2.5e-05 24.4 0.3 2.5e-05 24.4 0.2 1.8 2 0 0 2 2 2 1 PH domain CTNNB1_binding PF08347.6 EGC34772.1 - 0.0032 17.7 3.4 0.0051 17.1 2.3 1.3 1 0 0 1 1 1 1 N-terminal CTNNB1 binding UBN2_2 PF14227.1 EGC34772.1 - 0.023 14.2 3.2 0.037 13.5 2.2 1.4 1 0 0 1 1 1 0 gag-polypeptide of LTR copia-type DUF3810 PF12725.2 EGC34772.1 - 0.03 13.2 2.7 0.047 12.5 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3810) ORC5_C PF14630.1 EGC34772.1 - 0.032 13.6 1.8 0.045 13.2 1.3 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus DUF1002 PF06207.6 EGC34772.1 - 0.19 11.0 6.0 0.38 10.0 4.2 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1002) Ndc1_Nup PF09531.5 EGC34772.1 - 0.42 8.9 4.3 0.57 8.5 3.0 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Rsd_AlgQ PF04353.8 EGC34772.1 - 0.58 9.8 6.8 0.15 11.7 2.1 2.0 3 0 0 3 3 3 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ AAA_23 PF13476.1 EGC34773.1 - 7.5e-14 52.5 35.4 7.5e-14 52.5 24.6 5.3 2 1 1 3 3 3 1 AAA domain Metallophos_2 PF12850.2 EGC34773.1 - 3.7e-06 26.8 0.1 1.7e-05 24.6 0.0 2.1 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain SMC_N PF02463.14 EGC34773.1 - 7e-05 22.1 36.2 0.00045 19.5 2.0 3.5 3 1 0 3 3 3 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC34773.1 - 7.5e-05 22.1 0.0 0.00018 20.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain Metallophos PF00149.23 EGC34773.1 - 0.00056 19.3 0.1 0.002 17.5 0.1 2.0 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Reo_sigmaC PF04582.7 EGC34773.1 - 0.00086 18.5 1.9 0.00086 18.5 1.3 2.5 2 1 1 3 3 3 1 Reovirus sigma C capsid protein SbcCD_C PF13558.1 EGC34773.1 - 0.024 14.5 0.0 0.054 13.4 0.0 1.6 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_17 PF13207.1 EGC34773.1 - 2.4 9.0 0.0 2.4 9.0 0.0 3.8 2 1 0 2 2 2 0 AAA domain AAA_21 PF13304.1 EGC34773.1 - 4.4 7.1 60.0 0.41 10.5 16.9 5.2 2 1 1 3 3 3 0 AAA domain FNIP PF05725.7 EGC34774.1 - 1.7e-37 127.1 38.5 8.9e-13 47.9 2.8 7.1 5 2 1 6 6 6 5 FNIP Repeat Laminin_EGF PF00053.19 EGC34775.1 - 0.39 10.6 27.6 0.71 9.8 8.0 2.9 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC34775.1 - 0.71 10.0 8.7 0.18 11.9 1.1 2.9 2 0 0 2 2 2 0 Human growth factor-like EGF EGF_2 PF07974.8 EGC34775.1 - 3.4 7.8 20.5 2.5 8.3 1.3 3.4 2 0 0 2 2 2 0 EGF-like domain HECT PF00632.20 EGC34776.1 - 5.1e-89 298.5 1.2 1.1e-88 297.4 0.9 1.6 1 0 0 1 1 1 1 HECT-domain (ubiquitin-transferase) S1 PF00575.18 EGC34777.1 - 4.7e-07 29.7 5.6 0.0044 17.0 0.0 4.9 3 2 1 4 4 4 2 S1 RNA binding domain Suf PF05843.9 EGC34777.1 - 0.0043 16.8 0.8 0.0043 16.8 0.6 5.3 2 1 3 5 5 5 3 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGC34777.1 - 0.02 15.2 0.0 14 6.0 0.0 3.2 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC34777.1 - 0.025 15.0 0.0 0.17 12.3 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34777.1 - 0.027 15.1 0.0 1.3 9.7 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC34777.1 - 0.028 15.0 0.0 6.9 7.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat EMP70 PF02990.11 EGC34778.1 - 9.9e-94 314.6 19.6 9.9e-94 314.6 13.6 1.5 1 1 0 1 1 1 1 Endomembrane protein 70 FNIP PF05725.7 EGC34779.1 - 2.8e-18 65.6 16.8 0.00011 22.1 0.9 6.3 4 3 1 6 6 6 4 FNIP Repeat zf-C3HC4_2 PF13923.1 EGC34779.1 - 2.5e-05 24.2 15.4 2.5e-05 24.2 10.7 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC34779.1 - 0.00013 21.7 12.4 0.00013 21.7 8.6 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC34779.1 - 0.0013 18.3 11.0 0.0013 18.3 7.7 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-TRAF PF02176.13 EGC34779.1 - 0.025 14.9 2.8 0.025 14.9 2.0 3.3 2 1 0 2 2 2 0 TRAF-type zinc finger zf-Di19 PF05605.7 EGC34779.1 - 0.036 14.1 1.3 0.036 14.1 0.9 3.4 3 1 0 3 3 3 0 Drought induced 19 protein (Di19), zinc-binding DUF1246 PF06849.7 EGC34779.1 - 0.077 12.7 0.1 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1246) zf-Nse PF11789.3 EGC34779.1 - 0.26 10.8 9.7 1.2 8.7 6.7 2.2 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EGC34779.1 - 1.2 8.9 19.8 0.31 10.7 11.0 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC34779.1 - 9.5 6.4 12.6 2.3 8.3 3.4 2.7 2 0 0 2 2 2 0 RING-H2 zinc finger Pro-kuma_activ PF09286.6 EGC34780.1 - 5.3e-30 104.3 0.1 1.2e-29 103.1 0.1 1.6 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC34780.1 - 1.5e-08 34.1 1.0 3e-08 33.1 0.7 1.4 1 0 0 1 1 1 1 Subtilase family CBM49 PF09478.5 EGC34781.1 - 4.2e-13 49.1 3.1 4.2e-13 49.1 2.1 2.1 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 DUF3689 PF12463.3 EGC34782.1 - 1.2e-25 89.9 9.2 1.2e-25 89.9 6.4 2.9 2 1 0 2 2 2 1 Protein of unknown function (DUF3689) CENP-B_dimeris PF09026.5 EGC34782.1 - 0.0022 18.2 1.7 1.4 9.1 0.2 2.7 2 0 0 2 2 2 2 Centromere protein B dimerisation domain Trefoil PF00088.13 EGC34782.1 - 0.012 15.2 0.2 0.027 14.0 0.1 1.5 1 0 0 1 1 1 0 Trefoil (P-type) domain Pex14_N PF04695.8 EGC34782.1 - 4 7.4 9.1 5.2 7.1 2.2 2.3 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TM2 PF05154.11 EGC34783.1 - 2.7e-17 62.6 9.0 3.7e-17 62.2 6.2 1.2 1 0 0 1 1 1 1 TM2 domain BioY PF02632.9 EGC34783.1 - 0.00072 19.2 0.4 0.00095 18.8 0.2 1.1 1 0 0 1 1 1 1 BioY family GDI PF00996.13 EGC34784.1 - 1.5e-63 214.6 12.3 3.8e-63 213.3 8.5 1.6 1 1 0 1 1 1 1 GDP dissociation inhibitor tRNA-synt_1c PF00749.16 EGC34784.1 - 0.1 11.2 5.0 0.17 10.5 3.5 1.4 1 0 0 1 1 1 0 tRNA synthetases class I (E and Q), catalytic domain FNIP PF05725.7 EGC34785.1 - 1.2e-155 505.2 49.3 1.9e-15 56.4 0.1 12.2 12 0 0 12 12 12 12 FNIP Repeat Phage_min_tail PF05939.8 EGC34785.1 - 1.2e-07 31.5 0.3 27 4.7 0.0 7.6 3 2 5 8 8 8 2 Phage minor tail protein DUF249 PF03158.8 EGC34785.1 - 0.0093 15.5 0.1 26 4.2 0.0 5.6 4 3 4 8 8 8 1 Multigene family 530 protein DUF1769 PF08588.5 EGC34785.1 - 0.33 10.9 27.6 0.73 9.8 0.1 10.3 6 3 7 13 13 13 0 Protein of unknown function (DUF1769) Rhomboid PF01694.17 EGC34786.1 - 1.9e-14 53.9 14.1 4e-14 52.8 9.8 1.5 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EGC34786.1 - 0.011 16.0 4.7 0.011 16.0 3.2 2.3 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) tRNA_bind PF01588.15 EGC34787.1 - 6e-20 70.8 0.3 7.6e-14 51.3 0.0 2.1 2 0 0 2 2 2 2 Putative tRNA binding domain Tox-REase-2 PF15646.1 EGC34787.1 - 0.12 12.2 0.1 0.18 11.7 0.1 1.2 1 0 0 1 1 1 0 Restriction endonuclease fold toxin 2 CHB_HEX_C_1 PF13290.1 EGC34787.1 - 0.38 10.5 2.9 11 5.8 0.0 2.4 2 1 0 2 2 2 0 Chitobiase/beta-hexosaminidase C-terminal domain Myosin_head PF00063.16 EGC34788.1 - 9.5e-270 896.4 2.9 1.4e-269 895.9 2.0 1.2 1 0 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC34788.1 - 2.1e-44 151.2 2.9 2.6e-44 150.9 1.3 1.7 2 0 0 2 2 2 1 Myosin tail SH3_1 PF00018.23 EGC34788.1 - 1.3e-15 56.5 0.1 2.6e-15 55.5 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC34788.1 - 5.6e-15 54.6 0.0 1.3e-14 53.5 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC34788.1 - 2.5e-11 42.8 0.0 5.8e-11 41.7 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain AAA_18 PF13238.1 EGC34788.1 - 0.0032 17.7 0.4 0.021 15.1 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC34788.1 - 0.0085 16.0 0.0 0.033 14.1 0.0 1.9 2 0 0 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGC34788.1 - 0.016 15.3 0.1 0.073 13.2 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC34788.1 - 0.02 15.7 2.2 0.13 13.0 0.0 3.3 4 0 0 4 4 4 0 AAA domain Zeta_toxin PF06414.7 EGC34788.1 - 0.024 13.7 0.0 0.05 12.6 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin Hpr_kinase_C PF07475.7 EGC34788.1 - 0.046 13.0 0.6 2.3 7.5 0.0 2.5 2 0 0 2 2 2 0 HPr Serine kinase C-terminal domain ABC_tran PF00005.22 EGC34788.1 - 0.066 13.5 0.2 0.22 11.8 0.1 1.9 1 1 0 1 1 1 0 ABC transporter Sigma54_activ_2 PF14532.1 EGC34788.1 - 0.07 13.1 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain ArfGap PF01412.13 EGC34791.1 - 7.4e-44 148.2 0.6 9.1e-44 147.9 0.4 1.1 1 0 0 1 1 1 1 Putative GTPase activating protein for Arf tRNA-synt_2d PF01409.15 EGC34791.1 - 0.075 12.2 0.0 0.093 11.9 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class II core domain (F) Tmpp129 PF10272.4 EGC34791.1 - 0.15 10.7 1.7 0.19 10.3 1.2 1.2 1 0 0 1 1 1 0 Putative transmembrane protein precursor Myticin-prepro PF10690.4 EGC34791.1 - 0.17 11.9 0.8 0.45 10.5 0.3 1.8 1 1 1 2 2 2 0 Myticin pre-proprotein from the mussel DZR PF12773.2 EGC34791.1 - 1.3 8.9 4.4 3.1 7.6 3.0 1.7 1 1 0 1 1 1 0 Double zinc ribbon Pkinase PF00069.20 EGC34792.1 - 1e-52 178.8 0.5 5.2e-40 137.2 0.1 2.2 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC34792.1 - 1.2e-29 103.1 0.0 4.8e-23 81.5 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC34792.1 - 1.1e-05 24.5 0.0 1.7e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Kinase-like A_deaminase PF00962.17 EGC34793.1 - 8.3e-50 169.5 0.0 1.2e-49 168.9 0.0 1.2 1 0 0 1 1 1 1 Adenosine/AMP deaminase A_deaminase_N PF08451.6 EGC34793.1 - 3.7e-12 46.0 0.8 1e-11 44.6 0.6 1.8 1 0 0 1 1 1 1 Adenosine/AMP deaminase N-terminal Senescence_reg PF04520.8 EGC34794.1 - 0.023 15.1 9.6 0.57 10.6 0.3 2.6 1 1 1 2 2 2 0 Senescence regulator CENP-B_dimeris PF09026.5 EGC34794.1 - 0.12 12.5 1.6 0.4 10.9 1.1 1.9 1 0 0 1 1 1 0 Centromere protein B dimerisation domain Spore_III_AF PF09581.5 EGC34794.1 - 0.92 9.3 7.7 1.6 8.5 5.3 1.4 1 0 0 1 1 1 0 Stage III sporulation protein AF (Spore_III_AF) CbiK PF06180.6 EGC34796.1 - 0.0037 16.3 0.1 0.01 14.9 0.0 1.8 1 1 0 1 1 1 1 Cobalt chelatase (CbiK) IFN-gamma PF00714.12 EGC34797.1 - 0.11 12.2 0.0 0.12 12.1 0.0 1.0 1 0 0 1 1 1 0 Interferon gamma Folate_carrier PF01770.13 EGC34798.1 - 5 5.5 4.9 7 5.0 3.4 1.1 1 0 0 1 1 1 0 Reduced folate carrier Glyco_tranf_2_3 PF13641.1 EGC34799.1 - 2e-24 86.6 0.0 9.2e-24 84.5 0.0 1.9 2 0 0 2 2 2 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGC34799.1 - 1.8e-23 83.2 0.1 1.8e-23 83.2 0.0 2.7 3 0 0 3 3 3 1 Glycosyl transferase family group 2 Cellulose_synt PF03552.9 EGC34799.1 - 2.9e-18 65.5 24.5 5e-13 48.2 1.3 4.4 4 1 1 5 5 5 4 Cellulose synthase Glycos_transf_2 PF00535.21 EGC34799.1 - 9.5e-09 35.1 0.0 5.3e-08 32.7 0.0 2.3 2 0 0 2 2 2 1 Glycosyl transferase family 2 Glyco_transf_21 PF13506.1 EGC34799.1 - 2.2e-07 30.3 0.0 4.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 21 UBX PF00789.15 EGC34800.1 - 5.3e-10 39.2 0.0 1.1e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 UBX domain Abhydro_lipase PF04083.11 EGC34801.1 - 4.6e-20 70.7 0.1 1.6e-19 69.0 0.0 1.9 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EGC34801.1 - 2.5e-09 37.0 0.0 2.4e-08 33.8 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34801.1 - 1.4e-08 34.6 0.1 4.3e-08 33.0 0.0 1.7 2 0 0 2 2 2 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC34801.1 - 2.4e-05 24.3 0.0 4.9e-05 23.3 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydro_lipase PF04083.11 EGC34803.1 - 7e-17 60.5 0.0 2.9e-16 58.5 0.0 2.0 2 0 0 2 2 2 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EGC34803.1 - 6.8e-12 45.3 0.0 5.9e-11 42.3 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34803.1 - 7.4e-09 35.5 0.2 6.4e-08 32.4 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC34803.1 - 3.2e-05 23.9 0.0 5.7e-05 23.0 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGC34803.1 - 0.14 11.5 0.0 0.43 9.9 0.0 1.7 2 0 0 2 2 2 0 Serine hydrolase (FSH1) Abhydro_lipase PF04083.11 EGC34804.1 - 8e-17 60.3 0.1 4.3e-16 58.0 0.0 2.3 3 0 0 3 3 3 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_5 PF12695.2 EGC34804.1 - 2.1e-11 43.7 0.0 6.4e-10 38.9 0.0 2.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34804.1 - 9.2e-11 41.7 0.2 8.1e-10 38.6 0.1 2.0 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC34804.1 - 2.6e-06 27.5 0.0 6e-06 26.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGC34804.1 - 0.013 15.0 0.0 0.061 12.7 0.0 1.9 2 0 0 2 2 2 0 Serine hydrolase (FSH1) DUF4146 PF13652.1 EGC34804.1 - 0.092 12.5 0.0 0.17 11.6 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4146) Dicty_CTDC PF00526.13 EGC34805.1 - 7.6e-05 22.4 19.8 0.00013 21.6 2.6 11.4 12 1 0 12 12 12 5 Dictyostelium (slime mold) repeat Methyltransf_4 PF02390.12 EGC34806.1 - 1.2e-27 96.2 0.0 1.2e-27 96.2 0.0 2.5 2 1 0 2 2 2 1 Putative methyltransferase PPR_2 PF13041.1 EGC34806.1 - 7.4e-14 51.4 6.5 4.8e-05 23.2 0.4 4.0 1 1 3 4 4 4 4 PPR repeat family PPR PF01535.15 EGC34806.1 - 4.3e-09 35.7 1.6 0.003 17.4 0.0 4.1 3 0 0 3 3 3 2 PPR repeat PPR_3 PF13812.1 EGC34806.1 - 9.6e-05 22.3 0.1 0.74 10.2 0.0 4.1 4 0 0 4 4 4 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGC34806.1 - 0.00018 20.9 1.2 0.29 10.6 0.0 3.3 3 0 0 3 3 3 1 PPR repeat RRM_5 PF13893.1 EGC34806.1 - 0.036 13.9 0.2 6 6.7 0.0 2.7 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34806.1 - 0.043 13.8 0.0 0.12 12.3 0.0 1.9 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGC34806.1 - 1.2 7.5 36.9 2.4 6.5 25.6 1.4 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF974 PF06159.8 EGC34807.1 - 2.6e-73 246.5 0.2 2.6e-73 246.5 0.2 2.0 2 1 0 2 2 2 1 Protein of unknown function (DUF974) Transglut_C PF00927.17 EGC34807.1 - 1e-05 25.5 0.2 0.029 14.4 0.0 3.0 2 0 0 2 2 2 2 Transglutaminase family, C-terminal ig like domain PAT1 PF09770.4 EGC34807.1 - 0.15 10.2 25.2 0.19 9.9 17.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Utp21 PF04192.7 EGC34808.1 - 0.0073 15.4 0.3 0.017 14.2 0.2 1.6 1 0 0 1 1 1 1 Utp21 specific WD40 associated putative domain Hydrolase_4 PF12146.3 EGC34809.1 - 2.5e-24 84.8 0.0 4.2e-24 84.1 0.0 1.4 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EGC34809.1 - 1.6e-14 54.3 0.0 1.7e-14 54.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC34809.1 - 1.8e-12 47.1 0.0 2.1e-12 47.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC34809.1 - 0.00095 18.7 0.0 0.0011 18.5 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Esterase PF00756.15 EGC34809.1 - 0.0014 18.0 0.0 0.0021 17.4 0.0 1.2 1 0 0 1 1 1 1 Putative esterase Abhydrolase_2 PF02230.11 EGC34809.1 - 0.0073 15.7 0.0 3.2 7.1 0.0 2.2 2 0 0 2 2 2 2 Phospholipase/Carboxylesterase Abhydrolase_3 PF07859.8 EGC34809.1 - 0.036 13.6 0.0 0.051 13.1 0.0 1.2 1 0 0 1 1 1 0 alpha/beta hydrolase fold zf-CCHC PF00098.18 EGC34810.1 - 1.4e-06 27.8 1.4 2.2e-06 27.2 1.0 1.3 1 0 0 1 1 1 1 Zinc knuckle ABC_membrane_3 PF13748.1 EGC34812.1 - 1.9 7.4 4.3 2.9 6.8 3.0 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region G8 PF10162.4 EGC34813.1 - 9.5e-30 102.9 0.1 2.6e-29 101.5 0.0 1.8 1 0 0 1 1 1 1 G8 domain RRM_1 PF00076.17 EGC34814.1 - 4.3e-56 186.4 4.4 7.6e-21 73.5 0.1 3.3 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC34814.1 - 4.6e-42 141.8 0.4 1.9e-13 50.1 0.1 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC34814.1 - 8e-36 121.6 2.7 3.9e-13 49.0 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC34814.1 - 0.0067 16.1 0.1 4.2 7.1 0.0 3.0 3 0 0 3 3 3 2 Limkain b1 CSD PF00313.17 EGC34814.1 - 0.24 11.2 1.9 12 5.7 0.1 3.1 3 0 0 3 3 3 0 'Cold-shock' DNA-binding domain UBX PF00789.15 EGC34815.1 - 1.9e-13 50.2 0.2 6.2e-13 48.6 0.0 1.9 2 0 0 2 2 2 1 UBX domain Folate_carrier PF01770.13 EGC34815.1 - 0.091 11.2 0.5 0.72 8.3 0.0 2.0 2 0 0 2 2 2 0 Reduced folate carrier Peptidase_S46 PF10459.4 EGC34815.1 - 0.1 10.9 7.6 0.12 10.7 5.3 1.1 1 0 0 1 1 1 0 Peptidase S46 KID PF02524.9 EGC34815.1 - 0.74 10.1 3.9 3.4 8.2 0.2 3.5 2 0 0 2 2 2 0 KID repeat Rotamase PF00639.16 EGC34815.1 - 5.7 7.7 9.5 6.9 7.4 0.8 3.5 2 2 1 3 3 3 0 PPIC-type PPIASE domain Proteasome PF00227.21 EGC34816.1 - 4e-41 140.4 0.0 4.5e-41 140.2 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit Chromo PF00385.19 EGC34817.1 - 4.5e-09 35.8 0.5 1.2e-08 34.4 0.3 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain rve PF00665.21 EGC34817.1 - 0.00087 19.3 0.0 0.0015 18.6 0.0 1.4 1 0 0 1 1 1 1 Integrase core domain rve_3 PF13683.1 EGC34817.1 - 0.0032 16.9 0.2 0.0091 15.5 0.0 1.9 2 1 1 3 3 3 1 Integrase core domain Tudor-knot PF11717.3 EGC34817.1 - 0.0088 15.7 1.3 0.02 14.5 0.9 1.7 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain Hce2 PF14856.1 EGC34817.1 - 0.009 15.9 0.2 3.4 7.6 0.0 2.4 2 1 0 2 2 2 2 Pathogen effector; putative necrosis-inducing factor Mistic PF11458.3 EGC34817.1 - 0.29 11.5 2.1 13 6.2 0.0 2.8 2 2 2 4 4 4 0 Membrane-integrating protein Mistic ABC_membrane_3 PF13748.1 EGC34818.1 - 2.2 7.2 4.4 3.4 6.6 3.1 1.4 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2763 PF10961.3 EGC34820.1 - 1.5e-15 57.3 21.0 1.6e-14 54.0 14.5 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF2763) ASFV_L11L PF05293.6 EGC34820.1 - 0.027 14.5 0.1 0.036 14.1 0.0 1.1 1 0 0 1 1 1 0 African swine fever virus (ASFV) L11L protein M_domain PF12938.2 EGC34820.1 - 3.6 7.3 6.9 4.6 6.9 4.8 1.2 1 0 0 1 1 1 0 M domain of GW182 LSM PF01423.17 EGC34821.1 - 1.8e-18 65.8 0.0 2.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 LSM domain AAA_11 PF13086.1 EGC34822.1 - 1.1 8.7 7.3 1.4 8.4 5.1 1.3 1 0 0 1 1 1 0 AAA domain Transketolase_N PF00456.16 EGC34822.1 - 6.8 5.3 7.4 9.2 4.9 5.1 1.1 1 0 0 1 1 1 0 Transketolase, thiamine diphosphate binding domain Exonuc_VII_L PF02601.10 EGC34822.1 - 7.9 5.5 16.1 9.8 5.2 11.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit NIF PF03031.13 EGC34823.1 - 1.4e-08 34.5 0.1 1.7e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase Aurora-A_bind PF09041.5 EGC34823.1 - 0.089 12.5 0.1 0.092 12.5 0.1 1.2 1 0 0 1 1 1 0 Aurora-A binding FNIP PF05725.7 EGC34824.1 - 2.7e-52 174.4 63.0 2e-12 46.8 1.3 9.6 4 3 6 11 11 11 10 FNIP Repeat DDE_3 PF13358.1 EGC34827.1 - 7.9e-13 48.3 0.2 1.1e-12 47.8 0.2 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease rve PF00665.21 EGC34827.1 - 0.025 14.6 0.0 0.035 14.2 0.0 1.2 1 0 0 1 1 1 0 Integrase core domain DDE_1 PF03184.14 EGC34827.1 - 0.03 13.4 0.2 0.034 13.2 0.2 1.1 1 0 0 1 1 1 0 DDE superfamily endonuclease Peptidase_M1 PF01433.15 EGC34828.1 - 9.6e-19 67.7 5.9 9.6e-19 67.7 4.1 3.4 3 1 0 3 3 3 1 Peptidase family M1 MIP-T3 PF10243.4 EGC34828.1 - 0.00013 20.5 101.4 0.00013 20.5 70.3 4.6 1 1 3 4 4 4 1 Microtubule-binding protein MIP-T3 EF-hand_1 PF00036.27 EGC34833.1 - 3.4e-13 47.8 0.0 0.00018 20.5 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_5 PF13202.1 EGC34833.1 - 3.3e-11 41.9 0.0 0.00016 20.8 0.0 3.3 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGC34833.1 - 4.2e-11 41.7 0.0 0.00097 18.8 0.0 3.6 3 0 0 3 3 3 3 EF-hand domain EF-hand_7 PF13499.1 EGC34833.1 - 1.3e-08 34.8 0.0 3.2e-06 27.1 0.0 2.5 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC34833.1 - 0.00032 20.2 0.0 0.0057 16.2 0.0 2.7 2 1 1 3 3 3 2 EF-hand domain pair VID27 PF08553.5 EGC34835.1 - 0.029 12.6 1.5 0.032 12.4 1.1 1.0 1 0 0 1 1 1 0 VID27 cytoplasmic protein DUF2457 PF10446.4 EGC34835.1 - 0.033 12.9 2.0 0.041 12.6 1.4 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DNA_pol_phi PF04931.8 EGC34835.1 - 0.14 9.9 5.0 0.15 9.7 3.4 1.1 1 0 0 1 1 1 0 DNA polymerase phi LAT PF15234.1 EGC34835.1 - 3.3 7.1 7.1 4.2 6.7 4.9 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells zf-RVT PF13966.1 EGC34836.1 - 0.063 13.6 2.2 0.075 13.3 0.9 1.7 1 1 1 2 2 2 0 zinc-binding in reverse transcriptase Thermopsin PF05317.6 EGC34836.1 - 0.18 10.6 0.7 0.21 10.4 0.5 1.1 1 0 0 1 1 1 0 Thermopsin FNIP PF05725.7 EGC34838.1 - 1.8e-17 63.0 48.5 1e-09 38.1 1.0 9.4 5 4 4 9 9 9 8 FNIP Repeat UPF0014 PF03649.8 EGC34839.1 - 0.16 11.1 0.0 0.29 10.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0014) IBN_N PF03810.14 EGC34840.1 - 0.00013 21.8 0.4 0.00013 21.8 0.3 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain NIT PF08376.5 EGC34840.1 - 0.21 11.1 0.1 0.37 10.2 0.1 1.3 1 0 0 1 1 1 0 Nitrate and nitrite sensing MCM PF00493.18 EGC34841.1 - 1.9e-101 339.2 0.0 1.9e-101 339.2 0.0 3.2 2 1 1 3 3 3 1 MCM2/3/5 family AAA_5 PF07728.9 EGC34841.1 - 2.1e-07 30.7 0.0 5.2e-07 29.4 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGC34841.1 - 2.5e-06 26.8 0.1 0.0033 16.6 0.0 2.6 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGC34841.1 - 0.0042 16.6 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA PF00004.24 EGC34841.1 - 0.0071 16.5 0.1 0.0071 16.5 0.1 2.5 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC34841.1 - 0.023 14.8 0.1 0.1 12.7 0.1 2.2 1 0 0 1 1 1 0 AAA domain Alpha_kinase PF02816.13 EGC34842.1 - 5.9e-45 153.2 3.1 1.1e-44 152.3 2.1 1.5 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 EGC34842.1 - 6.9e-06 26.2 0.0 1.1e-05 25.6 0.0 1.3 1 0 0 1 1 1 1 von Willebrand factor type A domain Alpha_kinase PF02816.13 EGC34843.1 - 1e-38 132.8 0.3 1.8e-38 132.0 0.2 1.3 1 0 0 1 1 1 1 Alpha-kinase family VWA_2 PF13519.1 EGC34843.1 - 0.0001 22.4 0.0 0.00014 21.9 0.0 1.2 1 0 0 1 1 1 1 von Willebrand factor type A domain Phage_Gp14 PF10666.4 EGC34844.1 - 0.12 12.2 0.1 0.22 11.3 0.0 1.3 1 0 0 1 1 1 0 Phage protein Gp14 Neur_chan_memb PF02932.11 EGC34845.1 - 0.12 12.2 4.4 0.18 11.6 3.1 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF4199 PF13858.1 EGC34845.1 - 0.14 12.1 3.2 0.23 11.3 2.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) CemA PF03040.9 EGC34845.1 - 0.17 11.4 6.1 0.21 11.1 3.9 1.3 1 1 0 1 1 1 0 CemA family TACC PF05010.9 EGC34845.1 - 1 9.0 13.8 4.8 6.8 9.7 1.8 1 1 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) Transglut_core PF01841.14 EGC34846.1 - 4.8e-13 49.3 0.0 9.6e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 Transglutaminase-like superfamily ER PF01133.12 EGC34846.1 - 0.19 11.4 0.1 0.19 11.4 0.1 3.0 3 1 0 3 3 3 0 Enhancer of rudimentary RP-C_C PF11800.3 EGC34846.1 - 6.1 6.4 6.1 15 5.1 4.2 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region Peptidase_C39_2 PF13529.1 EGC34847.1 - 2.7e-14 53.7 0.1 2.4e-13 50.6 0.0 2.0 1 1 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 EGC34847.1 - 0.00093 19.0 0.5 0.0036 17.1 0.0 2.2 2 1 0 2 2 2 1 Peptidase C39 family Adenine_glyco PF03352.8 EGC34848.1 - 2.9e-68 228.8 0.1 3.3e-68 228.7 0.1 1.0 1 0 0 1 1 1 1 Methyladenine glycosylase Peptidase_S8 PF00082.17 EGC34850.1 - 1e-36 126.5 0.1 1.6e-36 125.9 0.1 1.3 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.8 EGC34850.1 - 0.11 12.6 14.8 0.24 11.6 10.2 1.6 1 0 0 1 1 1 0 EGF-like domain Peptidase_S8 PF00082.17 EGC34851.1 - 8.1e-38 130.1 1.3 1.3e-37 129.4 0.9 1.3 1 0 0 1 1 1 1 Subtilase family EGF_2 PF07974.8 EGC34851.1 - 0.005 16.9 10.9 0.005 16.9 7.5 2.5 2 0 0 2 2 2 1 EGF-like domain EGF PF00008.22 EGC34851.1 - 0.017 15.1 10.1 0.017 15.1 7.0 2.8 2 0 0 2 2 2 0 EGF-like domain hEGF PF12661.2 EGC34851.1 - 0.93 9.7 3.9 2.8 8.2 2.7 1.9 1 0 0 1 1 1 0 Human growth factor-like EGF ABC_membrane PF00664.18 EGC34852.1 - 1.1e-65 221.7 35.9 6.8e-35 120.8 11.1 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC34852.1 - 8.5e-49 165.3 0.9 6e-29 101.0 0.0 3.3 3 0 0 3 3 3 2 ABC transporter SMC_N PF02463.14 EGC34852.1 - 7.6e-10 38.3 0.1 0.012 14.8 0.0 4.2 2 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC34852.1 - 2e-05 23.9 1.7 0.015 14.8 0.2 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Zeta_toxin PF06414.7 EGC34852.1 - 3e-05 23.2 0.5 0.13 11.3 0.0 2.5 2 0 0 2 2 2 2 Zeta toxin Miro PF08477.8 EGC34852.1 - 4.5e-05 23.9 0.8 0.022 15.2 0.0 2.9 2 0 0 2 2 2 1 Miro-like protein DUF258 PF03193.11 EGC34852.1 - 0.00034 19.8 1.3 0.0094 15.1 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGC34852.1 - 0.00037 20.4 0.4 0.51 10.3 0.0 2.7 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_17 PF13207.1 EGC34852.1 - 0.00052 20.8 0.3 2.2 9.1 0.0 3.6 3 0 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGC34852.1 - 0.00085 18.7 0.3 2.2 7.6 0.1 3.2 3 0 0 3 3 3 2 AAA domain AAA_16 PF13191.1 EGC34852.1 - 0.0029 17.5 1.0 0.15 12.0 0.2 2.7 2 0 0 2 2 2 1 AAA ATPase domain AAA_21 PF13304.1 EGC34852.1 - 0.0083 16.1 15.3 0.4 10.5 0.0 5.6 4 2 1 6 6 6 2 AAA domain FtsK_SpoIIIE PF01580.13 EGC34852.1 - 0.0095 15.4 0.2 1.1 8.7 0.0 2.4 2 0 0 2 2 2 1 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EGC34852.1 - 0.012 14.2 0.6 1.9 6.9 0.1 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Dynamin_N PF00350.18 EGC34852.1 - 0.014 15.2 0.4 0.014 15.2 0.3 2.8 3 0 0 3 3 3 0 Dynamin family AAA_10 PF12846.2 EGC34852.1 - 0.021 14.2 1.6 1.6 8.0 0.1 3.1 3 0 0 3 3 3 0 AAA-like domain T2SE PF00437.15 EGC34852.1 - 0.046 12.6 0.1 4.9 5.9 0.1 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_23 PF13476.1 EGC34852.1 - 0.051 13.8 11.9 0.44 10.8 0.0 4.3 4 0 0 4 4 4 0 AAA domain AAA_33 PF13671.1 EGC34852.1 - 0.064 13.1 0.1 1.3 8.8 0.1 2.6 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGC34852.1 - 0.081 12.4 0.1 14 5.2 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_22 PF13401.1 EGC34852.1 - 0.084 13.0 2.0 2.9 8.0 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGC34852.1 - 0.11 12.7 2.9 14 5.9 0.0 3.3 3 0 0 3 3 2 0 AAA domain DUF87 PF01935.12 EGC34852.1 - 1.9 8.2 7.6 1.4 8.6 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function DUF87 Rad1 PF02144.11 EGC34853.1 - 8.8e-59 198.5 1.5 1.2e-58 198.0 1.0 1.2 1 0 0 1 1 1 1 Repair protein Rad1/Rec1/Rad17 Ank_3 PF13606.1 EGC34854.1 - 6.8e-12 44.4 0.1 1.2e-05 25.0 0.0 3.7 3 0 0 3 3 3 3 Ankyrin repeat Ank_2 PF12796.2 EGC34854.1 - 4.6e-11 42.9 0.0 9.2e-11 41.9 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC34854.1 - 2.8e-08 33.1 0.1 6.9e-06 25.6 0.0 3.3 3 0 0 3 3 3 1 Ankyrin repeat Ank_4 PF13637.1 EGC34854.1 - 3.5e-07 30.5 0.1 7.6e-06 26.3 0.1 2.5 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC34854.1 - 3.8e-07 30.1 0.1 3.7e-06 26.9 0.0 2.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) zf-FCS PF06467.9 EGC34854.1 - 0.011 15.3 3.0 0.035 13.7 2.1 1.9 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF2572 PF10833.3 EGC34854.1 - 0.011 15.1 2.2 0.011 15.1 1.5 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2572) LSM PF01423.17 EGC34855.1 - 7.6e-09 35.0 0.0 8.7e-09 34.8 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC34855.1 - 0.0056 16.5 0.0 0.0058 16.5 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain LSM14 PF12701.2 EGC34855.1 - 0.044 13.5 0.1 0.046 13.5 0.0 1.1 1 0 0 1 1 1 0 Scd6-like Sm domain PPTA PF01239.17 EGC34857.1 - 3.6e-37 124.1 28.8 1.4e-09 36.8 1.0 6.3 6 0 0 6 6 6 5 Protein prenyltransferase alpha subunit repeat ATP-synt_E_2 PF08112.6 EGC34857.1 - 1.4 9.0 11.3 1.4 9.0 0.0 3.7 4 0 0 4 4 4 0 ATP synthase epsilon subunit DnaB_2 PF07261.6 EGC34857.1 - 5.8 6.6 8.2 0.82 9.3 0.2 3.3 4 0 0 4 4 4 0 Replication initiation and membrane attachment HTH_Tnp_4 PF13613.1 EGC34858.1 - 0.0036 16.7 0.2 0.0072 15.8 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease AMP-binding PF00501.23 EGC34859.1 - 7.8e-62 209.0 0.0 9.4e-62 208.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC34859.1 - 8.1e-09 36.3 0.0 1.5e-08 35.4 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Exo_endo_phos PF03372.18 EGC34860.1 - 2.6e-17 63.5 0.0 4e-17 62.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Corona_nucleoca PF00937.13 EGC34860.1 - 0.0068 15.4 5.8 0.0068 15.4 4.0 2.7 3 0 0 3 3 3 1 Coronavirus nucleocapsid protein SMN PF06003.7 EGC34860.1 - 7.9 5.4 17.5 6.6 5.7 4.3 2.4 2 0 0 2 2 2 0 Survival motor neuron protein (SMN) Coiled PF05710.7 EGC34861.1 - 0.052 14.0 0.1 0.055 13.9 0.1 1.1 1 0 0 1 1 1 0 Coiled coil GTP_EFTU PF00009.22 EGC34862.1 - 2.1e-60 203.3 0.0 3.3e-60 202.7 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_IV PF03764.13 EGC34862.1 - 4.1e-35 119.9 0.1 1e-34 118.6 0.1 1.7 1 0 0 1 1 1 1 Elongation factor G, domain IV EFG_II PF14492.1 EGC34862.1 - 4.3e-33 113.0 0.0 1.2e-32 111.5 0.0 1.9 1 0 0 1 1 1 1 Elongation Factor G, domain II EFG_C PF00679.19 EGC34862.1 - 1e-25 89.3 0.3 6.9e-25 86.7 0.1 2.5 3 0 0 3 3 3 1 Elongation factor G C-terminus GTP_EFTU_D2 PF03144.20 EGC34862.1 - 8.4e-13 48.2 0.0 2.3e-12 46.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC34862.1 - 0.0013 18.6 0.0 0.0038 17.1 0.0 1.8 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC34862.1 - 0.027 13.7 0.2 0.32 10.2 0.0 2.7 2 1 0 2 2 2 0 Ferrous iron transport protein B Miro PF08477.8 EGC34862.1 - 0.054 14.0 0.0 0.14 12.6 0.0 1.8 1 0 0 1 1 1 0 Miro-like protein BPL_LplA_LipB PF03099.14 EGC34864.1 - 2.3e-06 27.6 0.0 6.5e-06 26.1 0.0 1.7 1 1 0 1 1 1 1 Biotin/lipoate A/B protein ligase family SYS1 PF09801.4 EGC34865.1 - 6.6e-46 155.9 7.5 7.7e-46 155.6 5.2 1.0 1 0 0 1 1 1 1 Integral membrane protein S linking to the trans Golgi network Sugar_tr PF00083.19 EGC34865.1 - 0.0001 21.0 3.1 0.00013 20.6 2.2 1.1 1 0 0 1 1 1 1 Sugar (and other) transporter Ras PF00071.17 EGC34866.1 - 2.2e-59 199.4 0.1 2.5e-59 199.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34866.1 - 1.4e-16 61.0 0.0 2.1e-16 60.5 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC34866.1 - 1.3e-12 47.2 0.0 1.5e-12 47.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC34866.1 - 4.5e-06 26.6 0.0 6.5e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGC34866.1 - 2.5e-05 23.5 0.1 3.1e-05 23.2 0.1 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC34866.1 - 2.8e-05 23.6 0.0 0.00072 19.0 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC34866.1 - 0.00024 21.2 0.0 0.00065 19.8 0.0 1.7 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC34866.1 - 0.0011 18.2 0.0 0.0014 17.7 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PduV-EutP PF10662.4 EGC34866.1 - 0.0019 17.7 0.1 0.097 12.1 0.0 2.2 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation cobW PF02492.14 EGC34866.1 - 0.0052 16.2 0.0 0.023 14.1 0.0 1.8 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Arch_ATPase PF01637.13 EGC34866.1 - 0.0055 16.4 0.1 0.0091 15.7 0.0 1.3 1 0 0 1 1 1 1 Archaeal ATPase AAA_24 PF13479.1 EGC34866.1 - 0.0056 16.2 0.1 0.0094 15.5 0.1 1.3 1 0 0 1 1 1 1 AAA domain Septin PF00735.13 EGC34866.1 - 0.006 15.6 0.1 0.018 14.0 0.0 1.8 2 0 0 2 2 2 1 Septin MobB PF03205.9 EGC34866.1 - 0.0098 15.6 0.1 0.021 14.5 0.0 1.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B ATP_bind_1 PF03029.12 EGC34866.1 - 0.012 15.1 0.2 0.57 9.6 0.0 2.2 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein NTPase_1 PF03266.10 EGC34866.1 - 0.013 15.2 0.0 0.019 14.6 0.0 1.3 1 0 0 1 1 1 0 NTPase AAA_10 PF12846.2 EGC34866.1 - 0.02 14.3 0.1 0.035 13.5 0.1 1.3 1 0 0 1 1 1 0 AAA-like domain AAA_16 PF13191.1 EGC34866.1 - 0.021 14.7 0.0 0.045 13.7 0.0 1.6 2 0 0 2 2 2 0 AAA ATPase domain SRPRB PF09439.5 EGC34866.1 - 0.024 13.8 0.0 0.039 13.1 0.0 1.3 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_5 PF07728.9 EGC34866.1 - 0.028 14.1 0.0 0.087 12.5 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) NACHT PF05729.7 EGC34866.1 - 0.059 13.0 0.0 0.094 12.3 0.0 1.3 1 0 0 1 1 1 0 NACHT domain AAA_14 PF13173.1 EGC34866.1 - 0.13 12.2 0.0 0.23 11.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain PHD PF00628.24 EGC34868.1 - 1.6e-12 46.9 9.1 1.9e-12 46.6 6.3 1.1 1 0 0 1 1 1 1 PHD-finger C1_1 PF00130.17 EGC34868.1 - 0.37 10.5 7.9 0.071 12.8 1.7 2.1 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-dskA_traR PF01258.12 EGC34868.1 - 0.77 9.5 6.2 4.1 7.2 0.5 2.7 3 0 0 3 3 3 0 Prokaryotic dksA/traR C4-type zinc finger Prok-RING_1 PF14446.1 EGC34868.1 - 1.4 8.7 11.2 0.072 12.8 2.9 2.0 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 C1_3 PF07649.7 EGC34868.1 - 2 8.5 9.7 8.4 6.5 4.0 2.2 2 0 0 2 2 2 0 C1-like domain PHD_2 PF13831.1 EGC34868.1 - 6.7 6.1 9.6 0.9 8.9 3.9 1.7 2 1 0 2 2 2 0 PHD-finger Laminin_EGF PF00053.19 EGC34868.1 - 9.3 6.2 7.8 37 4.3 5.4 2.1 1 1 0 1 1 1 0 Laminin EGF-like (Domains III and V) Rtf2 PF04641.7 EGC34869.1 - 3e-09 36.4 38.1 5.3e-08 32.3 3.0 4.0 2 2 2 4 4 3 2 Rtf2 RING-finger zf-C3HC4_2 PF13923.1 EGC34869.1 - 1.4e-08 34.6 18.3 6.7e-05 22.8 2.2 2.9 2 1 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC34869.1 - 1.8e-06 27.6 17.2 0.0065 16.2 7.1 3.0 2 1 1 3 3 3 2 Ring finger domain Atg14 PF10186.4 EGC34869.1 - 9.2e-05 21.5 9.3 9.2e-05 21.5 6.5 1.5 2 0 0 2 2 1 1 UV radiation resistance protein and autophagy-related subunit 14 zf-C3HC4 PF00097.20 EGC34869.1 - 0.00013 21.4 18.3 0.041 13.5 2.3 3.2 2 1 1 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC34869.1 - 0.00059 19.5 22.9 0.038 13.7 9.6 2.9 2 1 1 3 3 3 2 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC34869.1 - 0.0018 17.9 12.6 0.011 15.4 2.6 3.1 2 0 0 2 2 2 2 RING-type zinc-finger Prok-RING_4 PF14447.1 EGC34869.1 - 0.002 17.6 3.1 0.002 17.6 2.2 3.3 2 2 2 4 4 3 1 Prokaryotic RING finger family 4 zf-C3HC4_4 PF15227.1 EGC34869.1 - 0.009 15.8 19.2 0.057 13.2 2.0 3.0 2 1 0 2 2 2 2 zinc finger of C3HC4-type, RING LRRC37AB_C PF14914.1 EGC34869.1 - 0.0096 15.3 4.3 0.017 14.5 3.0 1.4 1 0 0 1 1 1 1 LRRC37A/B like protein 1 C-terminal domain Rad50_zn_hook PF04423.9 EGC34869.1 - 0.016 14.6 1.2 0.016 14.6 0.8 3.9 4 1 0 4 4 3 0 Rad50 zinc hook motif TEX19 PF15553.1 EGC34869.1 - 0.039 13.8 2.4 0.072 12.9 1.6 1.5 1 0 0 1 1 1 0 Testis-expressed protein 19 DUF3439 PF11921.3 EGC34869.1 - 0.047 13.4 0.7 0.047 13.4 0.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Drc1-Sld2 PF11719.3 EGC34869.1 - 0.17 10.9 16.3 0.25 10.4 11.3 1.2 1 0 0 1 1 1 0 DNA replication and checkpoint protein IncA PF04156.9 EGC34869.1 - 1.3 8.6 4.9 2 7.9 3.4 1.3 1 0 0 1 1 1 0 IncA protein DUF106 PF01956.11 EGC34869.1 - 1.6 8.2 5.3 2.7 7.4 3.7 1.4 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF506 PF04720.7 EGC34869.1 - 2.3 7.7 11.4 3.8 7.0 7.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF506) DUF4337 PF14235.1 EGC34869.1 - 2.4 7.9 5.2 4.5 7.1 3.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DUF3987 PF13148.1 EGC34869.1 - 4.1 5.8 8.0 5.9 5.3 5.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) WH2 PF02205.15 EGC34870.1 - 3e-17 61.5 1.0 1.4e-06 27.6 0.2 3.1 3 0 0 3 3 3 3 WH2 motif SET PF00856.23 EGC34871.1 - 8e-28 97.7 0.3 2.2e-27 96.3 0.2 1.7 1 1 0 1 1 1 1 SET domain Pre-SET PF05033.11 EGC34871.1 - 2.9e-16 59.5 7.1 2.9e-16 59.5 5.0 2.0 2 0 0 2 2 2 1 Pre-SET motif EF-hand_1 PF00036.27 EGC34872.1 - 2.3e-24 82.7 8.6 1.1e-08 33.7 0.1 5.1 5 0 0 5 5 5 4 EF hand EF-hand_7 PF13499.1 EGC34872.1 - 3.4e-21 75.1 1.8 7.7e-11 41.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC34872.1 - 9.7e-21 71.7 4.8 1.1e-08 34.1 0.0 5.3 4 2 2 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 EGC34872.1 - 1e-12 46.7 5.0 1.4e-07 30.5 0.1 5.0 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 EGC34872.1 - 1.2e-10 40.7 8.0 0.0029 17.1 0.1 4.6 2 2 2 4 4 4 4 EF-hand domain pair EF-hand_9 PF14658.1 EGC34872.1 - 8.8e-10 38.3 0.1 5.1e-06 26.3 0.0 2.3 2 1 0 2 2 2 2 EF-hand domain UPF0154 PF03672.8 EGC34872.1 - 0.0004 19.9 0.2 0.67 9.6 0.0 3.1 2 1 1 3 3 3 1 Uncharacterised protein family (UPF0154) ChlamPMP_M PF07548.6 EGC34872.1 - 0.043 13.5 0.1 0.19 11.4 0.0 1.9 1 1 0 1 1 1 0 Chlamydia polymorphic membrane protein middle domain EF-hand_4 PF12763.2 EGC34872.1 - 0.088 12.5 1.2 1.9 8.2 0.0 2.6 1 1 2 3 3 3 0 Cytoskeletal-regulatory complex EF hand PBS_linker_poly PF00427.16 EGC34872.1 - 0.098 12.3 0.1 0.4 10.3 0.0 2.0 1 1 1 2 2 2 0 Phycobilisome Linker polypeptide Caleosin PF05042.8 EGC34872.1 - 0.1 12.1 0.4 0.48 9.9 0.3 2.1 1 1 0 1 1 1 0 Caleosin related protein Med7 PF05983.6 EGC34873.1 - 6.9e-49 165.7 10.8 6.9e-49 165.7 7.5 1.6 2 0 0 2 2 2 1 MED7 protein SMN PF06003.7 EGC34873.1 - 0.0033 16.5 2.4 0.0033 16.5 1.6 2.0 2 0 0 2 2 2 1 Survival motor neuron protein (SMN) TPR_1 PF00515.23 EGC34875.1 - 2.5e-57 188.2 23.2 4e-08 32.5 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGC34875.1 - 5.7e-57 189.2 36.5 2.3e-14 52.8 1.0 6.9 1 1 7 9 9 9 9 TPR repeat TPR_2 PF07719.12 EGC34875.1 - 3.6e-49 160.7 20.6 9.9e-06 25.0 0.0 9.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_8 PF13181.1 EGC34875.1 - 1.4e-37 124.5 12.9 6.7e-05 22.3 0.9 10.4 9 1 1 10 10 10 8 Tetratricopeptide repeat TPR_12 PF13424.1 EGC34875.1 - 5e-36 122.4 16.1 1e-07 31.8 0.0 6.8 3 1 4 7 7 7 7 Tetratricopeptide repeat TPR_17 PF13431.1 EGC34875.1 - 4.6e-31 104.4 38.9 0.00014 21.8 0.0 12.1 13 0 0 13 13 11 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGC34875.1 - 2.7e-29 101.1 23.6 5.2e-08 33.3 0.2 7.5 4 2 4 8 8 7 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGC34875.1 - 9.5e-25 84.3 9.6 0.0017 18.0 0.1 10.1 10 0 0 10 10 10 5 Tetratricopeptide repeat TPR_14 PF13428.1 EGC34875.1 - 1.5e-23 81.1 14.2 0.0063 17.0 0.0 9.6 5 2 5 10 10 9 7 Tetratricopeptide repeat TPR_6 PF13174.1 EGC34875.1 - 5.5e-22 76.6 20.8 0.036 14.5 0.0 9.8 9 0 0 9 9 9 6 Tetratricopeptide repeat TPR_19 PF14559.1 EGC34875.1 - 4.5e-17 62.1 24.8 1.3e-05 25.4 0.1 7.1 5 1 3 8 8 7 5 Tetratricopeptide repeat Apc3 PF12895.2 EGC34875.1 - 4e-12 46.1 17.8 1.3e-07 31.6 0.7 4.5 3 2 2 5 5 5 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_15 PF13429.1 EGC34875.1 - 1.5e-10 40.6 19.7 7.5e-05 21.9 1.5 4.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_20 PF14561.1 EGC34875.1 - 4.8e-05 23.3 16.8 0.22 11.6 0.0 6.9 4 2 3 7 7 6 1 Tetratricopeptide repeat ChAPs PF09295.5 EGC34875.1 - 5.2e-05 22.1 1.4 0.017 13.8 0.0 3.3 3 0 0 3 3 3 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_9 PF13371.1 EGC34875.1 - 0.00042 20.1 25.8 0.009 15.8 0.1 6.4 3 2 4 8 8 7 4 Tetratricopeptide repeat TPR_10 PF13374.1 EGC34875.1 - 0.01 15.7 14.7 5.1 7.1 0.0 6.3 8 0 0 8 8 6 0 Tetratricopeptide repeat Homeobox PF00046.24 EGC34876.1 - 2.1e-10 40.0 0.1 3.5e-10 39.3 0.1 1.3 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGC34876.1 - 3e-06 26.8 5.4 1.4e-05 24.6 1.1 2.8 2 1 1 3 3 3 2 Homeobox KN domain DUF4291 PF14124.1 EGC34877.1 - 1.2e-65 220.5 4.9 1.5e-65 220.2 3.4 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4291) Staphostatin_B PF09023.5 EGC34877.1 - 0.1 12.4 0.6 0.22 11.3 0.0 1.9 2 0 0 2 2 2 0 Staphostatin B Ribosomal_L50 PF10501.4 EGC34877.1 - 0.56 10.1 3.4 0.32 10.9 0.2 2.1 3 0 0 3 3 3 0 Ribosomal subunit 39S FPN1 PF06963.7 EGC34878.1 - 2.4e-80 270.0 7.9 2.8e-80 269.8 5.5 1.0 1 0 0 1 1 1 1 Ferroportin1 (FPN1) MFS_1 PF07690.11 EGC34878.1 - 1.4e-09 37.1 16.0 2.6e-09 36.2 6.6 2.3 2 0 0 2 2 2 2 Major Facilitator Superfamily DUF2955 PF11168.3 EGC34879.1 - 0.044 13.4 6.5 0.084 12.5 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2955) LIM PF00412.17 EGC34880.1 - 1.5e-12 47.4 2.3 3e-12 46.4 1.6 1.5 1 0 0 1 1 1 1 LIM domain AIF_C PF14721.1 EGC34880.1 - 0.043 14.0 3.5 0.074 13.3 2.4 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term Trypan_PARP PF05887.6 EGC34880.1 - 0.69 9.7 10.3 0.18 11.6 4.9 1.6 1 1 1 2 2 2 0 Procyclic acidic repetitive protein (PARP) Metallophos PF00149.23 EGC34882.1 - 6.9e-10 38.6 7.7 2.1e-09 37.0 5.3 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EGC34882.1 - 0.0036 15.9 0.1 0.0063 15.1 0.0 1.4 2 0 0 2 2 2 1 PhoD-like phosphatase Tetraspannin PF00335.15 EGC34882.1 - 4.9 6.3 7.7 2.2 7.4 0.2 3.0 3 0 0 3 3 3 0 Tetraspanin family DUF106 PF01956.11 EGC34883.1 - 1.1e-39 135.6 1.1 1.4e-39 135.3 0.7 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF106 Wbp11 PF09429.5 EGC34883.1 - 0.0014 18.5 6.4 0.002 18.0 4.4 1.2 1 0 0 1 1 1 1 WW domain binding protein 11 60KD_IMP PF02096.15 EGC34883.1 - 0.0017 18.0 0.1 0.0021 17.7 0.1 1.1 1 0 0 1 1 1 1 60Kd inner membrane protein TMCO5 PF14992.1 EGC34883.1 - 0.013 14.6 0.1 0.017 14.2 0.1 1.1 1 0 0 1 1 1 0 TMCO5 family DivIC PF04977.10 EGC34883.1 - 0.025 14.0 1.0 0.047 13.1 0.7 1.4 1 0 0 1 1 1 0 Septum formation initiator DUF3373 PF11853.3 EGC34883.1 - 0.033 12.7 1.1 0.043 12.3 0.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) HTH_WhiA PF02650.9 EGC34883.1 - 0.089 13.1 1.0 0.16 12.4 0.7 1.3 1 0 0 1 1 1 0 WhiA C-terminal HTH domain CHD5 PF04420.9 EGC34883.1 - 0.15 11.7 1.7 0.4 10.3 1.2 1.7 1 1 0 1 1 1 0 CHD5-like protein HTH_29 PF13551.1 EGC34884.1 - 1.4e-08 34.8 0.0 1.7e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGC34884.1 - 8.1e-07 28.4 2.4 8.2e-07 28.4 0.2 1.9 2 0 0 2 2 2 1 Helix-turn-helix domain HTH_23 PF13384.1 EGC34884.1 - 4.4e-06 26.1 0.1 9.5e-06 25.1 0.0 1.6 2 0 0 2 2 2 1 Homeodomain-like domain HTH_32 PF13565.1 EGC34884.1 - 7.8e-05 23.3 0.0 0.0002 22.1 0.0 1.6 1 1 1 2 2 2 1 Homeodomain-like domain HTH_7 PF02796.10 EGC34884.1 - 0.00027 20.7 0.3 0.0066 16.2 0.0 2.3 2 0 0 2 2 2 1 Helix-turn-helix domain of resolvase Sigma70_r4_2 PF08281.7 EGC34884.1 - 0.00051 19.4 0.0 0.0012 18.2 0.0 1.6 1 0 0 1 1 1 1 Sigma-70, region 4 CENP-B_N PF04218.8 EGC34884.1 - 0.0072 15.7 0.3 0.019 14.3 0.2 1.6 1 0 0 1 1 1 1 CENP-B N-terminal DNA-binding domain HTH_28 PF13518.1 EGC34884.1 - 0.0084 16.0 0.5 0.016 15.2 0.0 1.7 2 1 0 2 2 2 1 Helix-turn-helix domain HTH_Tnp_Tc3_2 PF01498.13 EGC34884.1 - 0.067 13.2 0.3 1.9 8.5 0.0 2.5 2 1 0 2 2 2 0 Transposase HTH_40 PF14493.1 EGC34884.1 - 0.13 12.5 0.3 0.16 12.2 0.2 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain DUF4214 PF13946.1 EGC34885.1 - 0.0024 17.5 0.0 0.0028 17.3 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4214) Ank_2 PF12796.2 EGC34886.1 - 4.9e-10 39.6 0.0 3e-05 24.2 0.0 1.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC34886.1 - 2.4e-08 33.4 0.0 0.02 15.0 0.0 3.8 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGC34886.1 - 1.2e-06 28.8 0.0 0.016 15.7 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC34886.1 - 0.00019 21.0 0.0 3.7 7.5 0.0 3.3 3 0 0 3 3 3 2 Ankyrin repeat Ank_5 PF13857.1 EGC34886.1 - 0.011 15.9 0.0 15 6.0 0.0 3.1 1 1 2 3 3 3 0 Ankyrin repeats (many copies) Lantibiotic_a PF14867.1 EGC34886.1 - 0.011 14.9 0.4 0.019 14.1 0.2 1.4 1 0 0 1 1 1 0 Lantibiotic alpha Aconitase PF00330.15 EGC34887.1 - 6.2e-177 588.7 0.2 1.1e-176 587.8 0.2 1.4 1 1 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGC34887.1 - 6.7e-47 158.8 0.0 1.6e-46 157.6 0.0 1.7 1 0 0 1 1 1 1 Aconitase C-terminal domain Adaptin_N PF01602.15 EGC34888.1 - 1.2e-161 538.6 18.0 1.8e-161 538.0 12.5 1.1 1 0 0 1 1 1 1 Adaptin N terminal region Cnd1 PF12717.2 EGC34888.1 - 4e-32 111.4 8.6 2e-31 109.2 0.5 3.2 3 1 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 B2-adapt-app_C PF09066.5 EGC34888.1 - 2.4e-26 91.8 0.1 5.3e-26 90.7 0.0 1.6 1 0 0 1 1 1 1 Beta2-adaptin appendage, C-terminal sub-domain HEAT_2 PF13646.1 EGC34888.1 - 2.4e-23 82.2 2.8 4.7e-09 36.3 0.0 5.9 4 1 2 6 6 6 5 HEAT repeats HEAT PF02985.17 EGC34888.1 - 2e-12 46.0 2.7 0.016 15.2 0.0 5.7 5 0 0 5 5 5 4 HEAT repeat Alpha_adaptinC2 PF02883.15 EGC34888.1 - 1.6e-05 25.1 0.2 4.4e-05 23.7 0.1 1.7 1 0 0 1 1 1 1 Adaptin C-terminal domain CLASP_N PF12348.3 EGC34888.1 - 2.4e-05 23.8 3.3 0.11 11.8 0.1 3.8 2 2 0 2 2 2 2 CLASP N terminal DUF2435 PF10363.4 EGC34888.1 - 0.00019 21.2 3.0 1.6 8.6 0.0 5.1 4 1 1 5 5 5 1 Protein of unknown function (DUF2435) Cnd3 PF12719.2 EGC34888.1 - 0.00083 18.4 5.7 0.00093 18.2 0.2 3.1 3 1 1 4 4 4 1 Nuclear condensing complex subunits, C-term domain Arm PF00514.18 EGC34888.1 - 0.0027 17.4 6.0 3.8 7.4 0.0 5.0 4 1 0 4 4 4 2 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EGC34888.1 - 0.0042 17.5 2.9 17 6.0 0.0 5.4 5 2 2 7 7 6 0 HEAT-like repeat TPR_19 PF14559.1 EGC34888.1 - 0.041 14.2 0.2 0.27 11.6 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat FNIP PF05725.7 EGC34889.1 - 6.6e-08 32.3 22.6 0.028 14.3 0.8 5.3 3 2 3 6 6 6 5 FNIP Repeat LRR_5 PF13306.1 EGC34889.1 - 0.0073 16.0 5.0 0.052 13.2 0.6 2.5 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) Lung_7-TM_R PF06814.8 EGC34891.1 - 2.6e-10 39.7 33.6 4.4e-10 39.0 23.3 1.4 1 0 0 1 1 1 1 Lung seven transmembrane receptor GpcrRhopsn4 PF10192.4 EGC34891.1 - 4.7e-07 29.2 22.6 4.7e-07 29.2 15.6 2.7 2 1 1 3 3 3 1 Rhodopsin-like GPCR transmembrane domain PH_4 PF15404.1 EGC34891.1 - 5.4 6.5 9.6 13 5.2 0.1 2.4 2 0 0 2 2 2 0 Pleckstrin homology domain Macro PF01661.16 EGC34892.1 - 8e-33 112.8 0.2 1.9e-32 111.6 0.1 1.7 1 0 0 1 1 1 1 Macro domain WWE PF02825.15 EGC34892.1 - 4.6e-15 54.7 19.5 8.7e-08 31.4 0.2 3.6 3 0 0 3 3 3 3 WWE domain bZIP_2 PF07716.10 EGC34893.1 - 7.5e-07 28.8 11.3 7.5e-07 28.8 7.8 3.0 4 0 0 4 4 4 1 Basic region leucine zipper bZIP_1 PF00170.16 EGC34893.1 - 1.3e-05 25.0 7.7 1.3e-05 25.0 5.4 2.8 3 0 0 3 3 3 1 bZIP transcription factor L27 PF02828.11 EGC34893.1 - 1.7 8.4 7.9 1.4 8.6 0.0 3.6 3 0 0 3 3 3 0 L27 domain zf-RING_2 PF13639.1 EGC34894.1 - 5.1e-10 39.0 2.7 2.7e-09 36.7 0.7 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGC34894.1 - 2.9e-05 23.6 3.6 7.7e-05 22.2 0.6 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC34894.1 - 0.00012 22.1 7.3 0.0014 18.6 5.1 2.1 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC34894.1 - 0.00013 21.5 2.3 0.0011 18.6 0.4 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC34894.1 - 0.00018 21.1 2.8 0.00032 20.3 0.5 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC34894.1 - 0.00019 21.3 2.5 0.00019 21.3 1.7 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGC34894.1 - 0.0066 16.2 1.4 0.0066 16.2 1.0 1.9 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC34894.1 - 0.0074 15.9 1.3 0.019 14.6 0.9 1.7 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC34894.1 - 0.016 15.0 0.7 0.016 15.0 0.5 1.9 2 0 0 2 2 2 0 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC34894.1 - 0.17 11.4 1.1 0.24 10.9 0.0 1.8 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 FANCL_C PF11793.3 EGC34894.1 - 2.1 8.3 9.3 1.4 8.9 3.1 2.5 2 1 0 2 2 2 0 FANCL C-terminal domain DUF4118 PF13493.1 EGC34894.1 - 6.5 7.0 22.5 3.7 7.7 12.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4118) IBR PF01485.16 EGC34895.1 - 3e-22 78.2 31.1 1.7e-14 53.4 4.7 3.8 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGC34895.1 - 4.1e-05 23.3 36.9 0.00025 20.8 4.7 3.5 3 0 0 3 3 3 2 Ring finger domain UBA PF00627.26 EGC34895.1 - 0.0037 17.0 0.0 0.0098 15.7 0.0 1.8 1 0 0 1 1 1 1 UBA/TS-N domain zf-RING_5 PF14634.1 EGC34895.1 - 0.0063 16.2 7.0 0.0063 16.2 4.8 3.7 2 1 1 3 3 3 2 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC34895.1 - 0.012 15.6 7.6 0.012 15.6 5.3 4.3 2 1 1 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Gpi1 PF05024.10 EGC34896.1 - 1.9e-49 167.8 16.9 1.9e-49 167.8 11.7 1.8 2 0 0 2 2 2 1 N-acetylglucosaminyl transferase component (Gpi1) Ribosomal_L22 PF00237.14 EGC34897.1 - 1.9e-23 82.4 1.0 2.5e-23 82.0 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L22p/L17e DUF3914 PF13053.1 EGC34897.1 - 0.98 9.6 7.8 1.6 8.9 4.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3914) Peptidase_C48 PF02902.14 EGC34898.1 - 2.4e-43 148.2 1.6 3.1e-43 147.9 1.1 1.1 1 0 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain 3Beta_HSD PF01073.14 EGC34899.1 - 4.3e-73 245.4 0.0 5.5e-73 245.0 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC34899.1 - 1e-35 123.2 0.0 1.4e-35 122.8 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGC34899.1 - 7.9e-17 60.9 0.0 9.7e-13 47.6 0.0 2.1 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EGC34899.1 - 6.1e-15 55.6 0.0 8.4e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC34899.1 - 3e-09 36.1 0.0 5e-09 35.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC34899.1 - 3.2e-09 36.1 0.2 8.6e-09 34.7 0.1 1.6 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGC34899.1 - 3.1e-06 26.6 0.0 4.7e-06 26.0 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family adh_short PF00106.20 EGC34899.1 - 0.0029 17.5 0.2 0.041 13.8 0.1 2.4 1 1 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC34899.1 - 0.0065 16.1 0.1 0.094 12.3 0.1 2.3 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EGC34899.1 - 0.011 14.7 0.1 0.017 14.1 0.0 1.3 1 0 0 1 1 1 0 Saccharopine dehydrogenase PAXNEB PF05625.6 EGC34901.1 - 6.8e-96 321.2 0.3 6.8e-96 321.2 0.2 2.5 2 0 0 2 2 2 1 PAXNEB protein DEAD PF00270.24 EGC34901.1 - 5.5e-16 58.5 0.0 1.4e-15 57.2 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC34901.1 - 1.1e-06 28.3 0.0 4.3e-06 26.5 0.0 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain KaiC PF06745.8 EGC34901.1 - 0.015 14.4 1.3 0.66 9.0 0.1 3.3 4 0 0 4 4 4 0 KaiC Biopterin_H PF00351.16 EGC34902.1 - 7.1e-164 544.3 0.1 8.7e-164 544.0 0.0 1.1 1 0 0 1 1 1 1 Biopterin-dependent aromatic amino acid hydroxylase ACT PF01842.20 EGC34902.1 - 0.0014 18.0 0.0 0.0031 16.9 0.0 1.6 1 0 0 1 1 1 1 ACT domain Cellulase PF00150.13 EGC34902.1 - 0.14 11.3 0.0 0.21 10.7 0.0 1.3 1 0 0 1 1 1 0 Cellulase (glycosyl hydrolase family 5) MTHFR PF02219.12 EGC34903.1 - 1.9e-119 398.0 0.0 2.9e-119 397.4 0.0 1.2 1 0 0 1 1 1 1 Methylenetetrahydrofolate reductase Chitin_bind_3 PF03067.10 EGC34904.1 - 1e-23 84.5 0.3 1.3e-23 84.2 0.2 1.1 1 0 0 1 1 1 1 Chitin binding domain Chitin_bind_3 PF03067.10 EGC34905.1 - 7.2e-38 130.6 1.0 8.3e-38 130.4 0.7 1.0 1 0 0 1 1 1 1 Chitin binding domain Hemerythrin PF01814.18 EGC34906.1 - 0.46 10.6 7.7 17 5.5 1.2 3.8 1 1 2 3 3 3 0 Hemerythrin HHE cation binding domain DUF3708 PF12501.3 EGC34906.1 - 9.3 6.0 6.9 4.2 7.1 0.3 2.5 1 1 0 2 2 2 0 Phosphate ATP-binding cassette transporter PMSR PF01625.16 EGC34907.1 - 9.9e-66 220.4 1.2 1.2e-65 220.1 0.8 1.0 1 0 0 1 1 1 1 Peptide methionine sulfoxide reductase TMEM51 PF15345.1 EGC34907.1 - 0.09 12.4 0.4 0.13 11.9 0.2 1.2 1 0 0 1 1 1 0 Transmembrane protein 51 Patched PF02460.13 EGC34908.1 - 3.6e-100 336.1 17.0 1.9e-99 333.7 7.0 2.8 2 1 1 3 3 3 2 Patched family Sterol-sensing PF12349.3 EGC34908.1 - 1e-49 167.9 8.3 1e-49 167.9 5.8 3.3 3 0 0 3 3 3 1 Sterol-sensing domain of SREBP cleavage-activation ACR_tran PF00873.14 EGC34908.1 - 0.00018 19.0 19.2 0.00032 18.2 13.3 1.3 1 0 0 1 1 1 1 AcrB/AcrD/AcrF family MMPL PF03176.10 EGC34908.1 - 0.00049 18.9 1.8 0.00049 18.9 1.3 2.6 2 0 0 2 2 2 1 MMPL family BAR_3_WASP_bdg PF10456.4 EGC34909.1 - 0.043 13.0 0.0 0.055 12.7 0.0 1.2 1 0 0 1 1 1 0 WASP-binding domain of Sorting nexin protein GpcrRhopsn4 PF10192.4 EGC34910.1 - 2.9e-70 236.3 17.7 2.9e-70 236.3 12.3 1.7 2 0 0 2 2 2 1 Rhodopsin-like GPCR transmembrane domain Lung_7-TM_R PF06814.8 EGC34910.1 - 0.00026 20.0 18.4 0.0008 18.4 12.8 1.8 1 1 0 1 1 1 1 Lung seven transmembrane receptor Pentapeptide PF00805.17 EGC34912.1 - 1e-43 145.9 39.9 5e-14 51.1 4.6 4.4 2 2 1 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGC34912.1 - 3.9e-28 97.0 11.9 2.8e-15 55.8 2.5 2.6 2 0 0 2 2 2 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EGC34912.1 - 3.9e-23 81.0 8.1 1.3e-08 34.5 2.9 5.0 1 1 2 4 4 4 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EGC34912.1 - 3.3e-17 62.4 0.0 6.3e-17 61.5 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain DUF3354 PF11834.3 EGC34912.1 - 1.4e-15 56.6 0.1 2.7e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3354) BTB PF00651.26 EGC34912.1 - 6e-05 23.0 0.0 0.00011 22.1 0.0 1.4 1 0 0 1 1 1 1 BTB/POZ domain DCX PF03607.12 EGC34912.1 - 0.0014 18.1 0.0 0.0043 16.5 0.0 1.8 2 0 0 2 2 2 1 Doublecortin NAD_binding_8 PF13450.1 EGC34912.1 - 0.062 13.3 0.0 0.4 10.7 0.0 2.4 3 0 0 3 3 3 0 NAD(P)-binding Rossmann-like domain RHH_3 PF12651.2 EGC34912.1 - 0.083 12.6 0.0 0.18 11.5 0.0 1.6 1 0 0 1 1 1 0 Ribbon-helix-helix domain COesterase PF00135.23 EGC34913.1 - 5.5e-128 427.9 0.1 6.2e-128 427.8 0.1 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC34913.1 - 4.7e-07 29.5 0.0 9.8e-07 28.5 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC34913.1 - 0.00012 21.3 0.0 0.00021 20.5 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC34913.1 - 0.0045 16.7 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Thg1 PF04446.7 EGC34914.1 - 5.8e-47 158.7 0.5 1.1e-46 157.7 0.2 1.6 2 0 0 2 2 2 1 tRNAHis guanylyltransferase Thg1C PF14413.1 EGC34914.1 - 4.8e-46 155.3 3.7 6.9e-46 154.8 2.6 1.3 1 0 0 1 1 1 1 Thg1 C terminal domain Cystatin PF00031.16 EGC34915.1 - 0.0027 17.7 0.7 0.0041 17.2 0.5 1.3 1 1 0 1 1 1 1 Cystatin domain CBM_X2 PF03442.9 EGC34915.1 - 0.037 13.8 0.2 0.039 13.7 0.2 1.1 1 0 0 1 1 1 0 Carbohydrate binding domain X2 DUF2540 PF10802.3 EGC34915.1 - 0.11 12.1 0.2 0.14 11.8 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2540) Pro-kuma_activ PF09286.6 EGC34916.1 - 4.8e-30 104.4 0.0 5.4e-30 104.3 0.0 1.0 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain HSP90 PF00183.13 EGC34917.1 - 5.7e-162 539.8 20.5 8.1e-162 539.3 14.2 1.2 1 0 0 1 1 1 1 Hsp90 protein HATPase_c_3 PF13589.1 EGC34917.1 - 1.9e-12 46.9 0.4 6e-12 45.3 0.3 1.9 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC34917.1 - 1.4e-08 34.4 0.7 5.9e-08 32.4 0.1 2.2 2 0 0 2 2 2 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Ribosomal_L24e PF01246.15 EGC34918.1 - 1.2e-20 73.0 0.6 1.2e-20 73.0 0.4 2.1 1 1 1 2 2 2 1 Ribosomal protein L24e Mucin PF01456.12 EGC34919.1 - 0.005 16.6 12.3 0.0096 15.7 8.5 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein SSP160 PF06933.6 EGC34919.1 - 0.018 13.0 9.5 0.024 12.6 6.6 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Ras PF00071.17 EGC34920.1 - 1.5e-29 102.4 0.3 1.7e-29 102.2 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34920.1 - 6.2e-10 39.6 0.1 8.7e-10 39.1 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC34920.1 - 0.0011 18.2 0.0 0.0013 17.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family CRISPR_Cas2 PF09827.4 EGC34920.1 - 0.12 12.5 0.1 0.23 11.5 0.1 1.5 1 0 0 1 1 1 0 CRISPR associated protein Cas2 zf-H2C2_2 PF13465.1 EGC34921.1 - 9.7e-19 66.6 40.5 1.1e-07 31.8 0.8 6.1 6 0 0 6 6 6 4 Zinc-finger double domain zf-C2H2 PF00096.21 EGC34921.1 - 2.5e-17 62.0 30.7 4.1e-05 23.6 0.8 5.3 5 0 0 5 5 5 4 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGC34921.1 - 2e-11 43.3 28.2 0.001 19.2 0.3 5.5 5 0 0 5 5 5 4 C2H2-type zinc finger zf-met PF12874.2 EGC34921.1 - 6.5e-05 22.9 8.1 0.84 9.9 0.4 4.7 4 0 0 4 4 4 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGC34921.1 - 0.047 13.8 2.3 0.047 13.8 1.6 5.1 5 0 0 5 5 5 0 Zinc-finger double-stranded RNA-binding TP1 PF02079.11 EGC34921.1 - 0.052 13.3 6.7 1.2 8.9 0.4 3.2 1 1 2 3 3 3 0 Nuclear transition protein 1 PGP_phosphatase PF09419.5 EGC34924.1 - 6.2e-50 168.8 0.0 7.8e-50 168.5 0.0 1.1 1 0 0 1 1 1 1 Mitochondrial PGP phosphatase Hydrolase_like PF13242.1 EGC34924.1 - 1.7e-06 27.6 0.0 3.1e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGC34924.1 - 3.9e-05 24.1 0.1 0.027 14.9 0.0 2.1 1 1 1 2 2 2 2 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGC34924.1 - 0.077 12.5 1.8 0.12 11.8 0.5 1.8 2 1 0 2 2 2 0 haloacid dehalogenase-like hydrolase Acyltransferase PF01553.16 EGC34925.1 - 3.4e-20 71.8 0.0 6.3e-20 70.9 0.0 1.4 1 0 0 1 1 1 1 Acyltransferase OTU PF02338.14 EGC34926.1 - 1.1e-12 48.5 1.5 2.8e-12 47.2 0.0 2.3 2 1 1 3 3 3 1 OTU-like cysteine protease TIG PF01833.19 EGC34927.1 - 6.4e-16 58.1 59.1 0.00077 19.3 4.0 7.8 5 2 1 7 7 7 7 IPT/TIG domain EGF_2 PF07974.8 EGC34927.1 - 0.42 10.8 10.6 1.2 9.3 7.3 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 EGC34928.1 - 1.5e-15 56.9 59.6 0.0017 18.3 1.5 8.0 5 3 2 7 7 7 7 IPT/TIG domain EGF_2 PF07974.8 EGC34928.1 - 0.43 10.7 10.6 1.2 9.3 7.3 1.8 1 0 0 1 1 1 0 EGF-like domain PAH PF02671.16 EGC34929.1 - 0.0085 15.6 2.3 0.12 11.9 0.3 3.4 3 0 0 3 3 3 1 Paired amphipathic helix repeat WD40 PF00400.27 EGC34930.1 - 3e-32 109.3 15.9 2.8e-06 27.0 0.7 7.1 7 0 0 7 7 7 6 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGC34930.1 - 0.00068 18.0 0.1 0.042 12.1 0.0 2.6 3 0 0 3 3 3 2 Cytochrome D1 heme domain PQQ PF01011.16 EGC34930.1 - 0.013 14.9 0.0 0.075 12.5 0.0 2.3 2 0 0 2 2 2 0 PQQ enzyme repeat YL1_C PF08265.6 EGC34930.1 - 0.11 12.0 0.5 0.4 10.2 0.4 2.0 2 0 0 2 2 2 0 YL1 nuclear protein C-terminal domain Cpn60_TCP1 PF00118.19 EGC34933.1 - 1.3e-43 149.3 22.2 2.2e-43 148.6 15.4 1.3 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Transferase PF02458.10 EGC34934.1 - 1.1e-15 57.0 0.0 1.4e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC34934.1 - 0.0033 16.3 0.0 0.0048 15.7 0.0 1.3 1 0 0 1 1 1 1 Condensation domain DUF162 PF02589.10 EGC34937.1 - 6.5e-20 71.4 0.0 7.4e-20 71.2 0.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YkgG family COG1556 NHL PF01436.16 EGC34937.1 - 0.02 14.8 0.3 0.13 12.2 0.0 2.3 2 0 0 2 2 2 0 NHL repeat SRP_SPB PF02978.14 EGC34938.1 - 2.2e-08 34.2 0.2 2.2e-08 34.2 0.2 2.2 2 0 0 2 2 2 1 Signal peptide binding domain SR-25 PF10500.4 EGC34938.1 - 0.0081 15.6 6.4 0.012 15.1 4.5 1.3 1 0 0 1 1 1 1 Nuclear RNA-splicing-associated protein Presenilin PF01080.12 EGC34938.1 - 0.45 9.2 2.5 0.58 8.9 1.8 1.2 1 0 0 1 1 1 0 Presenilin eIF3_p135 PF12807.2 EGC34938.1 - 8.3 6.3 9.2 9.5 6.1 5.9 1.5 1 1 0 1 1 1 0 Translation initiation factor eIF3 subunit 135 FtsJ PF01728.14 EGC34939.1 - 5.6e-51 173.0 0.0 6.3e-51 172.9 0.0 1.0 1 0 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_31 PF13847.1 EGC34939.1 - 1.5e-05 24.6 0.0 0.0002 20.9 0.0 2.1 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC34939.1 - 0.00039 20.1 0.0 0.0024 17.6 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC34939.1 - 0.0016 18.8 0.0 0.0034 17.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC34939.1 - 0.0017 17.5 0.0 0.0087 15.2 0.0 1.9 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family PCMT PF01135.14 EGC34939.1 - 0.0039 16.7 0.0 0.03 13.8 0.0 2.0 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGC34939.1 - 0.0088 16.6 0.0 0.16 12.5 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC34939.1 - 0.03 14.3 0.0 0.05 13.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain FNIP PF05725.7 EGC34941.1 - 4.4e-37 125.7 0.0 3.1e-11 43.0 0.0 5.1 3 1 2 5 5 5 5 FNIP Repeat LRR_5 PF13306.1 EGC34941.1 - 0.00023 20.8 0.1 0.0038 16.9 0.1 2.2 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) EGF_2 PF07974.8 EGC34942.1 - 2.6e-17 62.6 122.7 3.3e-05 23.9 9.8 7.1 7 0 0 7 7 7 5 EGF-like domain Laminin_EGF PF00053.19 EGC34942.1 - 1.5e-05 24.8 89.5 0.091 12.6 6.0 6.7 5 1 1 6 6 6 5 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC34943.1 - 1.1e-20 73.4 124.0 3e-05 24.0 8.8 6.9 7 0 0 7 7 7 6 EGF-like domain Laminin_EGF PF00053.19 EGC34943.1 - 5e-06 26.3 102.2 0.05 13.5 5.2 6.9 6 1 1 7 7 7 6 Laminin EGF-like (Domains III and V) SfsA PF03749.8 EGC34943.1 - 0.18 11.2 0.3 0.5 9.7 0.1 1.7 2 0 0 2 2 2 0 Sugar fermentation stimulation protein DUF2648 PF10855.3 EGC34944.1 - 0.091 12.2 0.5 0.22 10.9 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) EF-hand_7 PF13499.1 EGC34945.1 - 2e-20 72.6 10.0 4.9e-12 45.8 0.9 3.1 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC34945.1 - 3.2e-16 57.3 7.4 0.003 16.7 0.2 4.3 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC34945.1 - 1.3e-15 55.8 6.2 0.00072 19.2 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC34945.1 - 8.5e-08 31.2 2.2 0.71 9.3 0.0 4.7 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EGC34945.1 - 2.5e-06 27.4 2.6 0.008 16.1 0.1 2.5 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_8 PF13833.1 EGC34945.1 - 0.0014 18.1 7.0 0.21 11.2 0.4 3.3 3 0 0 3 3 3 2 EF-hand domain pair HTH_Tnp_IS630 PF01710.11 EGC34945.1 - 0.0085 15.7 0.9 0.011 15.3 0.4 1.4 1 1 0 1 1 1 1 Transposase DUF3811 PF11656.3 EGC34945.1 - 0.016 15.2 1.3 3.6 7.7 0.1 2.3 2 0 0 2 2 2 0 YjbD family (DUF3811) KIP1 PF07765.7 EGC34945.1 - 0.019 14.7 2.3 3.5 7.5 0.1 2.8 2 1 1 3 3 3 0 KIP1-like protein GlutR_dimer PF00745.15 EGC34945.1 - 0.035 14.0 1.6 2.3 8.1 0.2 2.4 2 1 0 2 2 2 0 Glutamyl-tRNAGlu reductase, dimerisation domain FDX-ACB PF03147.9 EGC34945.1 - 0.041 14.0 0.9 0.073 13.2 0.6 1.5 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain EF-hand_10 PF14788.1 EGC34945.1 - 0.053 13.1 1.2 2 8.1 0.0 2.6 2 1 0 2 2 2 0 EF hand EF-hand_like PF09279.6 EGC34945.1 - 0.072 13.1 3.1 8.4 6.4 0.1 2.8 1 1 2 3 3 3 0 Phosphoinositide-specific phospholipase C, efhand-like Raptor_N PF14538.1 EGC34945.1 - 0.15 11.8 0.8 0.26 11.1 0.1 1.8 2 1 1 3 3 3 0 Raptor N-terminal CASPase like domain DUF2624 PF11116.3 EGC34945.1 - 0.46 11.0 4.3 0.61 10.6 1.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2624) Fe_hyd_lg_C PF02906.9 EGC34945.1 - 1.5 8.0 5.4 6.1 6.0 0.5 2.6 1 1 2 3 3 3 0 Iron only hydrogenase large subunit, C-terminal domain DUF1637 PF07847.7 EGC34946.1 - 9.9e-39 132.7 0.2 1.2e-38 132.5 0.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1637) CDO_I PF05995.7 EGC34946.1 - 2.9e-07 29.8 0.0 4.2e-07 29.2 0.0 1.2 1 0 0 1 1 1 1 Cysteine dioxygenase type I EF-hand_1 PF00036.27 EGC34947.1 - 4.4e-15 53.7 8.4 4.7e-05 22.3 0.0 5.7 6 0 0 6 6 6 3 EF hand EF-hand_7 PF13499.1 EGC34947.1 - 3.4e-14 52.7 8.5 2.7e-06 27.4 0.2 4.0 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_8 PF13833.1 EGC34947.1 - 3.6e-13 48.9 9.6 5.5e-06 25.9 0.0 4.6 5 0 0 5 5 5 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC34947.1 - 6.3e-12 44.3 6.8 0.0078 16.0 0.0 5.1 4 1 1 5 5 5 4 EF-hand domain EF-hand_5 PF13202.1 EGC34947.1 - 3.6e-11 41.8 11.3 1.4e-05 24.2 0.1 5.7 6 1 0 6 6 6 2 EF hand EF-hand_4 PF12763.2 EGC34947.1 - 0.00022 20.8 2.8 0.0047 16.6 0.2 2.5 2 1 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGC34947.1 - 0.072 13.1 3.9 0.73 9.8 0.1 3.5 2 2 1 3 3 3 0 Secreted protein acidic and rich in cysteine Ca binding region LAGLIDADG_1 PF00961.14 EGC34947.1 - 1.7 9.2 8.4 0.24 11.9 2.0 2.2 2 1 0 2 2 2 0 LAGLIDADG endonuclease EF-hand_10 PF14788.1 EGC34947.1 - 3.8 7.2 6.5 7 6.4 0.0 3.3 4 0 0 4 4 4 0 EF hand NUDE_C PF04880.8 EGC34948.1 - 5e-11 43.2 3.1 5e-11 43.2 2.1 2.8 2 1 1 3 3 3 1 NUDE protein, C-terminal conserved region WEMBL PF05701.6 EGC34948.1 - 1.4e-07 30.3 25.1 2e-07 29.8 17.4 1.2 1 0 0 1 1 1 1 Weak chloroplast movement under blue light IncA PF04156.9 EGC34948.1 - 0.00085 18.9 23.1 0.00085 18.9 16.0 2.9 1 1 3 4 4 4 2 IncA protein Mnd1 PF03962.10 EGC34948.1 - 0.0035 17.0 27.6 0.19 11.3 7.3 2.4 1 1 1 2 2 2 2 Mnd1 family GAS PF13851.1 EGC34948.1 - 0.0038 16.4 25.4 0.0066 15.6 17.6 1.4 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding IFT57 PF10498.4 EGC34948.1 - 0.0051 15.6 27.1 0.042 12.5 19.1 1.9 1 1 0 1 1 1 1 Intra-flagellar transport protein 57 Serine_rich PF08824.5 EGC34948.1 - 0.24 11.1 10.1 0.32 10.6 4.5 2.3 1 1 1 2 2 2 0 Serine rich protein interaction domain MAT1 PF06391.8 EGC34948.1 - 0.26 10.8 30.5 0.076 12.5 14.3 2.3 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 TAF8_C PF10406.4 EGC34948.1 - 0.29 11.2 2.3 1.3 9.1 0.3 2.9 2 0 0 2 2 2 0 Transcription factor TFIID complex subunit 8 C-term Spc7 PF08317.6 EGC34948.1 - 0.33 9.5 32.4 0.21 10.1 10.0 2.3 1 1 1 2 2 2 0 Spc7 kinetochore protein NPV_P10 PF05531.7 EGC34948.1 - 0.33 11.2 14.2 5.5 7.3 0.1 3.8 1 1 2 3 3 3 0 Nucleopolyhedrovirus P10 protein Baculo_PEP_C PF04513.7 EGC34948.1 - 0.36 10.6 13.4 1.6 8.5 0.2 3.3 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Rab5-bind PF09311.6 EGC34948.1 - 0.38 10.6 34.8 0.49 10.2 22.1 2.4 1 1 0 1 1 1 0 Rabaptin-like protein CALCOCO1 PF07888.6 EGC34948.1 - 0.44 8.7 26.5 0.69 8.1 18.4 1.2 1 0 0 1 1 1 0 Calcium binding and coiled-coil domain (CALCOCO1) like Birna_RdRp PF04197.7 EGC34948.1 - 0.52 8.2 15.8 0.63 8.0 11.0 1.1 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) ATG16 PF08614.6 EGC34948.1 - 0.56 9.9 36.6 0.11 12.3 15.7 2.9 1 1 2 3 3 3 0 Autophagy protein 16 (ATG16) ERM PF00769.14 EGC34948.1 - 0.65 9.4 34.7 0.66 9.4 20.1 2.1 1 1 1 2 2 2 0 Ezrin/radixin/moesin family DUF904 PF06005.7 EGC34948.1 - 1.2 9.4 33.0 1.4 9.2 9.8 4.5 3 2 0 3 3 3 0 Protein of unknown function (DUF904) TMCO5 PF14992.1 EGC34948.1 - 1.7 7.6 32.4 0.1 11.7 11.6 2.6 1 1 1 2 2 2 0 TMCO5 family DUF972 PF06156.8 EGC34948.1 - 1.8 8.9 25.4 1.5 9.2 5.3 4.0 1 1 2 3 3 3 0 Protein of unknown function (DUF972) HAUS6_N PF14661.1 EGC34948.1 - 2.2 7.5 24.0 4.1 6.6 6.8 2.2 1 1 1 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus Lebercilin PF15619.1 EGC34948.1 - 2.3 7.5 32.2 1.9 7.8 13.2 2.4 1 1 1 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Reo_sigmaC PF04582.7 EGC34948.1 - 2.5 7.1 13.4 0.99 8.5 6.9 1.9 1 1 1 2 2 2 0 Reovirus sigma C capsid protein DUF3584 PF12128.3 EGC34948.1 - 3 5.0 29.5 5.7 4.1 20.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) TMPIT PF07851.8 EGC34948.1 - 4.1 6.3 22.0 0.2 10.6 7.4 2.5 1 1 2 3 3 3 0 TMPIT-like protein Atg14 PF10186.4 EGC34948.1 - 4.5 6.1 29.0 0.89 8.4 1.9 2.8 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 zf-C4H2 PF10146.4 EGC34948.1 - 4.6 7.1 25.6 0.16 12.0 7.3 2.1 1 1 1 2 2 2 0 Zinc finger-containing protein TPR_MLP1_2 PF07926.7 EGC34948.1 - 5.9 6.6 34.2 1.3 8.7 6.2 3.5 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Bacillus_HBL PF05791.6 EGC34948.1 - 9 5.6 17.0 1.1e+02 2.0 10.9 2.5 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) DUF763 PF05559.6 EGC34948.1 - 9.3 5.0 7.3 10 4.9 4.5 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF763) Fib_alpha PF08702.5 EGC34948.1 - 9.6 6.3 23.5 4.8 7.3 1.6 2.8 1 1 0 2 2 2 0 Fibrinogen alpha/beta chain family EF-hand_7 PF13499.1 EGC34949.1 - 4.9e-16 58.6 7.5 1.3e-10 41.2 0.9 2.6 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC34949.1 - 2.9e-14 51.5 5.9 0.00074 19.2 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_1 PF00036.27 EGC34949.1 - 9.1e-14 49.6 6.9 0.00045 19.3 0.1 4.3 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.4 EGC34949.1 - 5.1e-07 29.7 3.6 0.00074 19.5 0.5 2.9 1 1 2 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_5 PF13202.1 EGC34949.1 - 0.00022 20.4 4.8 0.098 12.0 0.0 4.0 4 0 0 4 4 4 2 EF hand EF-hand_10 PF14788.1 EGC34949.1 - 0.0016 18.0 2.1 1.4 8.6 0.0 2.7 3 0 0 3 3 3 2 EF hand EF-hand_8 PF13833.1 EGC34949.1 - 0.031 13.9 5.7 0.2 11.2 0.1 3.4 2 1 2 4 4 4 0 EF-hand domain pair EF-hand_7 PF13499.1 EGC34950.1 - 2.5e-20 72.3 13.2 9.5e-13 48.0 1.6 3.1 1 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC34950.1 - 6.9e-20 68.7 8.1 0.00023 20.2 0.2 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC34950.1 - 5.5e-16 56.9 8.7 0.00054 19.6 0.1 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGC34950.1 - 7.6e-11 41.4 12.5 0.0048 16.4 0.2 4.1 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EGC34950.1 - 3.5e-10 38.7 5.5 0.0046 16.2 0.1 4.4 4 0 0 4 4 4 4 EF hand SPARC_Ca_bdg PF10591.4 EGC34950.1 - 2.8e-09 36.9 3.8 2.6e-05 24.2 0.7 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3811 PF11656.3 EGC34950.1 - 0.0012 18.8 3.3 0.37 10.9 0.8 2.3 2 0 0 2 2 2 2 YjbD family (DUF3811) NCD2 PF04905.8 EGC34950.1 - 0.0073 16.1 1.5 0.018 14.8 0.2 1.9 1 1 1 2 2 2 1 NAB conserved region 2 (NCD2) EF-hand_like PF09279.6 EGC34950.1 - 0.039 13.9 2.0 7.3 6.6 0.1 2.9 1 1 1 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like DUF3216 PF11505.3 EGC34950.1 - 0.084 12.6 1.1 0.18 11.5 0.4 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3216) DltD_M PF04918.7 EGC34950.1 - 0.11 12.7 0.9 0.14 12.3 0.7 1.4 1 0 0 1 1 1 0 DltD central region DUF1103 PF06513.6 EGC34950.1 - 0.3 10.4 8.7 0.71 9.2 6.0 1.6 1 1 0 1 1 1 0 Repeat of unknown function (DUF1103) KIP1 PF07765.7 EGC34950.1 - 0.5 10.2 2.8 1.5 8.6 0.1 2.6 1 1 0 2 2 2 0 KIP1-like protein LMBR1 PF04791.11 EGC34951.1 - 2.6e-39 135.1 14.1 2.6e-39 135.1 9.8 3.5 2 1 1 3 3 3 1 LMBR1-like membrane protein PEPCK PF00821.13 EGC34952.1 - 8.1e-283 938.9 0.2 9.2e-283 938.7 0.1 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase Hydrolase_3 PF08282.7 EGC34952.1 - 0.029 13.9 0.4 0.061 12.8 0.3 1.4 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF1285 PF06938.6 EGC34952.1 - 0.1 12.5 0.0 0.2 11.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1285) Mito_carr PF00153.22 EGC34953.1 - 1e-59 198.2 3.7 3.1e-21 74.8 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF1785 PF08699.5 EGC34953.1 - 0.21 10.9 1.9 1.6 8.1 0.0 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF1785) SH3_9 PF14604.1 EGC34954.1 - 1.3e-15 56.6 0.1 3e-15 55.5 0.1 1.6 1 0 0 1 1 1 1 Variant SH3 domain FCH PF00611.18 EGC34954.1 - 8.6e-14 51.4 0.2 8.6e-14 51.4 0.1 3.4 3 1 0 3 3 3 1 Fes/CIP4, and EFC/F-BAR homology domain SH3_1 PF00018.23 EGC34954.1 - 2e-13 49.4 0.1 3.7e-13 48.6 0.1 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC34954.1 - 1.3e-10 40.6 0.0 2.5e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 Variant SH3 domain HR1 PF02185.11 EGC34954.1 - 2.7e-06 27.0 4.6 2.7e-06 27.0 3.2 3.6 3 0 0 3 3 3 1 Hr1 repeat GAS PF13851.1 EGC34954.1 - 0.0037 16.4 2.5 0.0037 16.4 1.7 2.3 2 0 0 2 2 2 1 Growth-arrest specific micro-tubule binding TPR_MLP1_2 PF07926.7 EGC34954.1 - 1.6 8.5 22.7 0.24 11.1 3.7 2.8 3 0 0 3 3 3 0 TPR/MLP1/MLP2-like protein DUF1664 PF07889.7 EGC34954.1 - 5.9 6.7 14.6 0.69 9.7 1.4 3.4 3 1 1 4 4 4 0 Protein of unknown function (DUF1664) ANAPC15 PF15243.1 EGC34954.1 - 6.9 6.8 8.1 8.6 6.5 2.4 2.9 3 0 0 3 3 3 0 Anaphase-promoting complex subunit 15 RasGAP PF00616.14 EGC34955.1 - 7.2e-35 120.4 1.8 2.6e-34 118.6 0.0 2.7 2 1 0 2 2 2 1 GTPase-activator protein for Ras-like GTPase CRAL_TRIO_2 PF13716.1 EGC34955.1 - 1.8e-18 66.8 1.8 5.4e-18 65.3 1.2 1.8 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EGC34955.1 - 4e-13 49.1 1.9 9.2e-13 47.9 1.3 1.6 1 0 0 1 1 1 1 CRAL/TRIO domain Myosin_TH1 PF06017.8 EGC34955.1 - 0.00015 21.1 4.0 0.099 11.9 0.2 2.4 2 0 0 2 2 2 2 Myosin tail Ras PF00071.17 EGC34956.1 - 1.3e-60 203.5 1.1 1.5e-60 203.2 0.7 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC34956.1 - 3.3e-19 69.5 0.5 5.5e-19 68.8 0.1 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC34956.1 - 3.1e-18 65.6 0.9 4.2e-18 65.1 0.6 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC34956.1 - 2.6e-10 39.8 1.0 3.2e-10 39.5 0.7 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC34956.1 - 5.5e-08 32.4 0.6 8.5e-08 31.8 0.3 1.4 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC34956.1 - 4.3e-07 29.8 0.5 1.2e-06 28.5 0.3 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC34956.1 - 5.7e-06 25.6 0.2 9.6e-05 21.6 0.0 2.0 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGC34956.1 - 9.3e-06 25.0 0.4 3.4e-05 23.1 0.3 1.8 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGC34956.1 - 0.0002 20.6 0.4 0.002 17.3 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function, DUF258 CPT PF07931.7 EGC34956.1 - 0.0041 16.7 0.0 0.0092 15.6 0.0 1.5 1 1 0 1 1 1 1 Chloramphenicol phosphotransferase-like protein AAA_22 PF13401.1 EGC34956.1 - 0.0069 16.5 0.1 0.023 14.8 0.0 1.9 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EGC34956.1 - 0.011 15.2 0.3 0.59 9.6 0.2 2.7 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EGC34956.1 - 0.033 13.7 0.0 0.16 11.5 0.0 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.1 EGC34956.1 - 0.041 12.9 0.0 0.093 11.7 0.0 1.6 1 1 1 2 2 2 0 AAA ATPase domain AAA_16 PF13191.1 EGC34956.1 - 0.045 13.7 0.3 0.095 12.6 0.2 2.0 1 1 0 1 1 1 0 AAA ATPase domain AAA_5 PF07728.9 EGC34956.1 - 0.06 13.0 0.1 0.13 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGC34956.1 - 0.067 13.4 0.2 0.18 12.0 0.1 1.9 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC34956.1 - 0.08 12.6 0.1 0.3 10.7 0.0 1.8 1 1 1 2 2 2 0 Archaeal ATPase ABC_tran PF00005.22 EGC34956.1 - 0.47 10.7 5.5 5.8 7.2 3.8 2.2 1 1 0 1 1 1 0 ABC transporter WD40 PF00400.27 EGC34957.1 - 1.4e-61 202.2 8.7 5.7e-08 32.3 0.0 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Mistic PF11458.3 EGC34957.1 - 0.058 13.8 0.0 0.61 10.5 0.0 2.4 2 0 0 2 2 2 0 Membrane-integrating protein Mistic Amino_oxidase PF01593.19 EGC34958.1 - 1.6e-42 146.1 0.0 4.3e-42 144.7 0.0 1.6 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC34958.1 - 6.5e-13 48.5 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGC34958.1 - 2.1e-05 24.6 0.2 0.0028 17.7 0.0 3.1 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGC34958.1 - 7.5e-05 21.7 0.0 0.00011 21.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain DAO PF01266.19 EGC34958.1 - 0.00011 21.3 0.0 0.00021 20.3 0.0 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase Lycopene_cycl PF05834.7 EGC34958.1 - 0.0028 16.6 0.0 0.54 9.1 0.0 2.1 2 0 0 2 2 2 2 Lycopene cyclase protein GIDA PF01134.17 EGC34958.1 - 0.0034 16.3 0.0 0.017 14.0 0.0 2.1 2 0 0 2 2 2 1 Glucose inhibited division protein A HI0933_like PF03486.9 EGC34958.1 - 0.0041 15.6 0.0 0.033 12.6 0.0 2.0 2 0 0 2 2 2 1 HI0933-like protein Pyr_redox PF00070.22 EGC34958.1 - 0.0052 17.1 0.2 0.051 13.9 0.0 2.5 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGC34958.1 - 0.013 14.6 0.0 0.026 13.6 0.0 1.4 1 0 0 1 1 1 0 Thi4 family Pyr_redox_2 PF07992.9 EGC34958.1 - 0.027 14.3 0.0 0.15 11.8 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC34958.1 - 0.13 11.3 0.0 0.38 9.7 0.0 1.7 2 0 0 2 2 2 0 FAD dependent oxidoreductase FNIP PF05725.7 EGC34960.1 - 5.2e-08 32.7 11.0 1.2e-05 25.1 0.5 3.2 3 0 0 3 3 3 3 FNIP Repeat PA14 PF07691.7 EGC34961.1 - 2.6e-16 59.5 0.5 4.6e-16 58.7 0.4 1.5 1 0 0 1 1 1 1 PA14 domain SURF2 PF05477.6 EGC34962.1 - 1.8e-11 43.6 39.3 1.8e-11 43.6 27.2 3.8 1 1 2 3 3 3 1 Surfeit locus protein 2 (SURF2) zf-C2H2_jaz PF12171.3 EGC34962.1 - 0.023 14.8 1.3 5 7.3 0.0 3.2 2 1 0 2 2 2 0 Zinc-finger double-stranded RNA-binding DUF605 PF04652.11 EGC34962.1 - 0.63 9.3 41.1 0.97 8.7 28.5 1.3 1 0 0 1 1 1 0 Vta1 like ChaB PF06150.7 EGC34963.1 - 3.7e-21 74.6 1.0 4.4e-21 74.4 0.7 1.1 1 0 0 1 1 1 1 ChaB IRF PF00605.12 EGC34963.1 - 0.025 14.3 0.4 0.039 13.7 0.2 1.5 1 1 0 1 1 1 0 Interferon regulatory factor transcription factor E1-E2_ATPase PF00122.15 EGC34964.1 - 6.1e-50 169.4 0.6 1.7e-49 167.9 0.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC34964.1 - 5.3e-18 66.2 0.0 2.6e-14 54.1 0.0 2.3 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase Cation_ATPase_C PF00689.16 EGC34964.1 - 4.6e-16 58.8 10.4 4.6e-16 58.8 7.2 2.4 3 0 0 3 3 3 1 Cation transporting ATPase, C-terminus HAD PF12710.2 EGC34964.1 - 2.2e-15 57.3 0.0 4.8e-15 56.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC34964.1 - 2.2e-14 52.6 0.0 1.4e-13 50.1 0.0 2.3 2 0 0 2 2 2 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGC34964.1 - 1.5e-06 28.0 0.0 3.6e-06 26.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGC34964.1 - 0.017 14.7 0.1 0.24 10.9 0.1 2.5 2 0 0 2 2 2 0 haloacid dehalogenase-like hydrolase FNIP PF05725.7 EGC34965.1 - 6e-23 80.5 73.4 4.6e-06 26.4 0.8 12.3 7 4 5 12 12 12 10 FNIP Repeat MFS_1 PF07690.11 EGC34966.1 - 1.1e-07 30.8 44.8 2.7e-07 29.6 9.6 2.6 1 1 1 2 2 2 2 Major Facilitator Superfamily UNC-93 PF05978.11 EGC34966.1 - 7.5e-06 25.5 7.1 7.5e-06 25.5 4.9 3.5 2 1 1 3 3 3 1 Ion channel regulatory protein UNC-93 Imm9 PF15561.1 EGC34966.1 - 0.041 13.4 0.2 0.097 12.2 0.2 1.6 1 0 0 1 1 1 0 Immunity protein 9 DUF3586 PF12131.3 EGC34967.1 - 0.012 15.6 0.4 0.012 15.6 0.3 3.0 2 1 1 3 3 3 0 Protein of unknown function (DUF3586) PRA-CH PF01502.13 EGC34967.1 - 0.11 12.1 1.5 1.3 8.7 0.1 2.5 2 0 0 2 2 2 0 Phosphoribosyl-AMP cyclohydrolase Peptidase_C71 PF12386.3 EGC34967.1 - 3 7.2 6.9 2.2 7.6 0.6 2.3 1 1 1 2 2 2 0 Pseudomurein endo-isopeptidase Pei YajC PF02699.10 EGC34968.1 - 0.015 14.9 0.1 0.096 12.3 0.0 2.4 1 0 0 1 1 1 0 Preprotein translocase subunit DUF3139 PF11337.3 EGC34968.1 - 0.077 13.2 0.4 0.077 13.2 0.3 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3139) UPF0172 PF03665.8 EGC34969.1 - 7.4e-39 133.2 0.0 7.9e-39 133.1 0.0 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0172) JAB PF01398.16 EGC34969.1 - 0.00012 21.7 0.0 0.00019 21.1 0.0 1.2 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Rhabdo_matrix PF03397.9 EGC34969.1 - 0.063 12.6 0.0 0.089 12.1 0.0 1.2 1 0 0 1 1 1 0 Rhabdovirus matrix protein Prok-JAB PF14464.1 EGC34969.1 - 0.063 12.8 0.0 0.097 12.2 0.0 1.3 1 0 0 1 1 1 0 Prokaryotic homologs of the JAB domain DUF2608 PF11019.3 EGC34969.1 - 0.069 12.1 0.3 0.24 10.3 0.2 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2608) SAPS PF04499.10 EGC34970.1 - 1.8e-77 261.0 4.5 3.2e-49 167.8 0.5 3.3 2 1 1 3 3 3 2 SIT4 phosphatase-associated protein CS PF04969.11 EGC34971.1 - 5.3e-12 46.1 0.4 8.2e-12 45.5 0.3 1.3 1 0 0 1 1 1 1 CS domain Adaptin_binding PF10199.4 EGC34972.1 - 4.9e-22 78.6 17.2 4.9e-22 78.6 11.9 2.2 2 0 0 2 2 2 1 Alpha and gamma adaptin binding protein p34 BESS PF02944.15 EGC34972.1 - 0.034 13.6 0.4 0.074 12.6 0.3 1.5 1 0 0 1 1 1 0 BESS motif Miro PF08477.8 EGC34972.1 - 0.041 14.3 0.2 0.041 14.3 0.1 2.3 2 1 0 2 2 2 0 Miro-like protein Pex24p PF06398.6 EGC34972.1 - 2.7 6.7 8.3 7.3 5.2 5.7 1.8 1 1 0 1 1 1 0 Integral peroxisomal membrane peroxin F5_F8_type_C PF00754.20 EGC34973.1 - 1.2e-24 86.6 1.6 2.4e-24 85.6 1.1 1.5 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC34973.1 - 1.1e-15 57.0 1.0 2.7e-15 55.7 0.7 1.7 1 0 0 1 1 1 1 H-type lectin domain DUF4094 PF13334.1 EGC34974.1 - 0.0089 16.3 0.1 0.024 15.0 0.1 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF4094) DUF1980 PF09323.5 EGC34974.1 - 0.013 15.2 0.5 0.013 15.2 0.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) SID-1_RNA_chan PF13965.1 EGC34974.1 - 0.032 12.4 0.6 0.044 11.9 0.4 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 ABC2_membrane_3 PF12698.2 EGC34974.1 - 0.11 11.5 0.2 0.12 11.3 0.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein PA26 PF04636.8 EGC34974.1 - 8.3 4.9 8.1 10 4.6 5.6 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) FNIP PF05725.7 EGC34975.1 - 2.8e-99 324.8 41.8 1.3e-14 53.7 1.1 9.1 6 2 2 9 9 9 9 FNIP Repeat Shigella_OspC PF06128.6 EGC34975.1 - 0.028 13.9 11.3 3.8 6.9 0.1 4.7 1 1 2 5 5 5 0 Shigella flexneri OspC protein Vac14_Fab1_bd PF12755.2 EGC34976.1 - 0.0081 16.5 2.3 0.04 14.3 0.1 3.0 3 0 0 3 3 3 1 Vacuolar 14 Fab1-binding region Nop25 PF09805.4 EGC34976.1 - 2.5 8.1 19.9 0.018 15.1 6.2 2.5 2 0 0 2 2 2 0 Nucleolar protein 12 (25kDa) Ribosomal_L4 PF00573.17 EGC34977.1 - 1.5e-42 145.1 1.1 1.5e-42 145.1 0.8 1.5 2 0 0 2 2 2 1 Ribosomal protein L4/L1 family Ribos_L4_asso_C PF14374.1 EGC34977.1 - 6.2e-26 90.1 7.7 2.1e-24 85.1 3.6 2.6 2 0 0 2 2 2 2 60S ribosomal protein L4 C-terminal domain WRC PF08879.5 EGC34979.1 - 0.0093 15.6 0.2 0.0093 15.6 0.2 4.5 2 1 2 4 4 4 1 WRC zf-rbx1 PF12678.2 EGC34979.1 - 1.2 9.2 8.0 0.73 9.9 1.0 2.3 2 0 0 2 2 2 0 RING-H2 zinc finger ArfGap PF01412.13 EGC34980.1 - 5.4e-32 110.0 0.2 5.4e-32 110.0 0.1 3.2 2 1 1 3 3 3 1 Putative GTPase activating protein for Arf VPS9 PF02204.13 EGC34981.1 - 3.7e-21 75.0 0.6 1.6e-20 73.0 0.1 2.4 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain G8 PF10162.4 EGC34982.1 - 0.019 14.7 2.8 0.37 10.6 0.1 3.6 2 1 1 4 4 4 0 G8 domain Proteasome PF00227.21 EGC34983.1 - 4.1e-45 153.4 0.1 5e-45 153.1 0.1 1.0 1 0 0 1 1 1 1 Proteasome subunit EF-hand_1 PF00036.27 EGC34984.1 - 4.3e-23 78.7 12.3 6e-08 31.4 0.2 4.5 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC34984.1 - 7.9e-20 68.9 6.6 3.3e-05 23.3 0.0 4.4 4 0 0 4 4 4 4 EF-hand domain EF-hand_7 PF13499.1 EGC34984.1 - 6.3e-19 67.8 9.4 1.4e-11 44.3 1.0 3.1 2 2 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC34984.1 - 2.5e-18 64.4 13.0 7.7e-07 28.1 0.6 4.6 5 0 0 5 5 5 3 EF hand EF-hand_8 PF13833.1 EGC34984.1 - 3.3e-16 58.6 9.2 8.2e-07 28.5 1.1 3.9 2 1 1 3 3 3 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC34984.1 - 2.9e-05 24.0 0.9 0.042 13.8 0.1 3.0 2 2 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGC34984.1 - 0.00053 19.8 0.2 0.16 11.8 0.0 3.0 3 1 0 3 3 3 1 EF-hand domain EF-hand_2 PF09068.6 EGC34984.1 - 0.0098 15.9 0.2 0.22 11.6 0.0 2.8 2 2 1 3 3 3 1 EF hand RMMBL PF07521.7 EGC34984.1 - 0.033 14.0 0.1 0.14 11.9 0.0 2.1 2 1 1 3 3 3 0 RNA-metabolising metallo-beta-lactamase DUF2492 PF10678.4 EGC34984.1 - 0.055 13.5 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2492) EAP30 PF04157.11 EGC34984.1 - 0.12 11.5 0.0 0.3 10.2 0.0 1.8 1 1 0 1 1 1 0 EAP30/Vps36 family FNIP PF05725.7 EGC34986.1 - 6.8e-123 400.4 69.6 1.4e-13 50.5 0.2 12.0 11 2 1 12 12 12 11 FNIP Repeat Phage_min_tail PF05939.8 EGC34986.1 - 0.00067 19.5 0.2 10 6.1 0.0 6.2 4 3 4 8 8 8 1 Phage minor tail protein DUF1769 PF08588.5 EGC34986.1 - 0.13 12.2 32.2 11 6.0 0.2 11.2 5 3 9 14 14 14 0 Protein of unknown function (DUF1769) zf-C2H2_6 PF13912.1 EGC34987.1 - 0.019 14.8 0.3 0.073 12.9 0.1 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger Sec23_trunk PF04811.10 EGC34988.1 - 9e-39 133.2 0.1 1.4e-38 132.6 0.1 1.3 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGC34988.1 - 6.1e-21 73.7 0.3 1.4e-20 72.6 0.2 1.7 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGC34988.1 - 6.4e-19 68.2 0.1 1.3e-18 67.3 0.0 1.5 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGC34988.1 - 8.6e-14 50.8 4.1 2.1e-13 49.5 2.8 1.7 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGC34988.1 - 0.0012 18.4 0.1 0.0033 17.0 0.0 1.8 1 0 0 1 1 1 1 Gelsolin repeat CRAL_TRIO PF00650.15 EGC34988.1 - 0.0018 17.8 0.1 0.79 9.2 0.0 2.4 2 0 0 2 2 2 2 CRAL/TRIO domain GTP1_OBG PF01018.17 EGC34989.1 - 1.6e-39 135.0 7.0 1.5e-24 86.4 2.6 2.3 2 0 0 2 2 2 2 GTP1/OBG MMR_HSR1 PF01926.18 EGC34989.1 - 9.5e-16 57.7 0.1 2.5e-15 56.4 0.1 1.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC34989.1 - 9.3e-06 25.0 0.5 0.07 12.4 0.0 3.0 2 1 1 3 3 3 2 Ferrous iron transport protein B NOG1 PF06858.9 EGC34989.1 - 0.077 12.8 0.0 11 6.0 0.0 2.5 2 0 0 2 2 2 0 Nucleolar GTP-binding protein 1 (NOG1) ArgK PF03308.11 EGC34989.1 - 0.15 10.8 0.1 2.4 6.8 0.0 2.2 2 0 0 2 2 2 0 ArgK protein DUF4106 PF13388.1 EGC34990.1 - 0.19 10.6 13.6 0.24 10.3 9.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4106) NST1 PF13945.1 EGC34990.1 - 0.7 9.9 10.7 1.3 9.0 7.4 1.4 1 0 0 1 1 1 0 Salt tolerance down-regulator AIF_C PF14721.1 EGC34990.1 - 1.1 9.4 6.2 2 8.6 4.3 1.4 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF4638 PF15472.1 EGC34990.1 - 3.9 6.9 9.6 16 5.0 4.3 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4638) BNIP3 PF06553.7 EGC34990.1 - 4.4 6.6 8.8 9.3 5.5 6.1 1.5 1 0 0 1 1 1 0 BNIP3 Ndc1_Nup PF09531.5 EGC34990.1 - 5.7 5.2 8.0 6.8 4.9 5.5 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Dynamin_N PF00350.18 EGC34991.1 - 1.7e-21 76.7 2.4 4.1e-21 75.5 0.1 2.3 2 0 0 2 2 2 1 Dynamin family MMR_HSR1 PF01926.18 EGC34991.1 - 9.8e-06 25.5 0.1 5.7e-05 23.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_23 PF13476.1 EGC34991.1 - 0.00055 20.3 8.4 0.023 15.0 0.5 3.0 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGC34991.1 - 0.005 16.7 0.7 0.041 13.7 0.0 3.0 3 0 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGC34991.1 - 0.02 14.6 0.2 0.16 11.6 0.0 2.4 2 0 0 2 2 2 0 Archaeal ATPase Dynamin_M PF01031.15 EGC34991.1 - 0.053 12.3 5.8 0.032 12.9 0.7 2.6 2 1 1 3 3 3 0 Dynamin central region AAA_29 PF13555.1 EGC34991.1 - 0.057 12.9 0.0 0.2 11.2 0.0 1.9 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EGC34991.1 - 0.15 11.7 0.0 0.43 10.2 0.0 1.8 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B zf-CCHC PF00098.18 EGC34992.1 - 7.3e-05 22.4 1.0 0.00012 21.7 0.7 1.4 1 0 0 1 1 1 1 Zinc knuckle Phi-29_GP4 PF05464.6 EGC34992.1 - 0.31 10.9 7.1 0.045 13.6 0.5 2.8 2 1 1 3 3 3 0 Phi-29-like late genes activator (early protein GP4) Microtub_assoc PF07989.6 EGC34992.1 - 4.4 7.2 21.0 3 7.7 0.5 4.5 2 1 2 4 4 4 0 Microtubule associated Chromo PF00385.19 EGC34993.1 - 1.9e-07 30.6 0.1 2.5e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC34993.1 - 0.088 12.5 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Kinesin PF00225.18 EGC34994.1 - 2.4e-83 279.6 0.3 2.7e-83 279.4 0.2 1.0 1 0 0 1 1 1 1 Kinesin motor domain Ubie_methyltran PF01209.13 EGC34998.1 - 4.7e-12 45.5 0.0 5.3e-12 45.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGC34998.1 - 1.6e-09 38.1 0.0 2e-09 37.8 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC34998.1 - 2.4e-08 33.7 0.0 3e-08 33.3 0.0 1.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC34998.1 - 2.6e-05 24.6 0.0 3.7e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC34998.1 - 0.0031 17.8 0.0 0.0042 17.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC34998.1 - 0.029 14.1 0.0 0.032 13.9 0.0 1.1 1 0 0 1 1 1 0 Methyltransferase domain zf-C3HC4_3 PF13920.1 EGC34999.1 - 4.2e-07 29.5 5.8 6.9e-07 28.8 4.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC34999.1 - 2e-05 24.1 11.4 0.00019 20.9 7.9 2.3 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC34999.1 - 2.7e-05 24.0 12.1 0.00047 20.1 8.5 2.3 1 1 1 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC34999.1 - 3.7e-05 23.3 9.6 8.4e-05 22.2 6.7 1.6 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC34999.1 - 0.00059 19.6 9.1 0.0017 18.1 6.3 1.8 1 1 0 1 1 1 1 Ring finger domain WBP-1 PF11669.3 EGC34999.1 - 0.001 19.0 0.5 0.002 18.1 0.3 1.5 1 0 0 1 1 1 1 WW domain-binding protein 1 zf-rbx1 PF12678.2 EGC34999.1 - 0.0036 17.3 4.2 0.0065 16.5 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC34999.1 - 0.0054 16.5 4.5 0.0054 16.5 3.1 2.5 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING RCR PF12273.3 EGC34999.1 - 0.0086 16.6 1.0 0.015 15.8 0.7 1.5 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red zf-RING_3 PF14369.1 EGC34999.1 - 0.015 15.2 1.6 0.037 14.0 1.1 1.7 1 0 0 1 1 1 0 zinc-finger Shisa PF13908.1 EGC34999.1 - 0.029 14.5 1.0 0.029 14.5 0.7 2.2 2 0 0 2 2 2 0 Wnt and FGF inhibitory regulator 7tm_1 PF00001.16 EGC34999.1 - 0.032 13.3 2.4 0.04 13.0 1.7 1.3 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) DUF843 PF05814.6 EGC34999.1 - 0.032 14.0 2.6 0.056 13.2 1.8 1.4 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) zf-RING_4 PF14570.1 EGC34999.1 - 0.037 13.5 8.4 0.083 12.4 5.8 1.6 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain DUF912 PF06024.7 EGC34999.1 - 0.04 13.9 0.6 0.04 13.9 0.4 2.0 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) RseA_N PF03872.8 EGC34999.1 - 0.067 13.4 0.1 0.16 12.3 0.0 1.6 1 0 0 1 1 1 0 Anti sigma-E protein RseA, N-terminal domain DUF3502 PF12010.3 EGC34999.1 - 0.09 12.7 2.4 0.97 9.4 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) MRAP PF15183.1 EGC34999.1 - 0.1 12.1 0.4 0.24 11.0 0.2 1.5 1 0 0 1 1 1 0 Melanocortin-2 receptor accessory protein family CitMHS PF03600.11 EGC34999.1 - 0.11 11.1 0.1 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Citrate transporter Prok-RING_4 PF14447.1 EGC34999.1 - 0.15 11.5 4.4 0.44 10.1 3.1 1.7 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 YajC PF02699.10 EGC34999.1 - 0.27 10.9 3.0 3 7.5 0.7 2.2 2 0 0 2 2 2 0 Preprotein translocase subunit zf-RING_6 PF14835.1 EGC34999.1 - 0.31 10.8 4.3 1.4 8.7 2.9 2.0 1 1 0 1 1 1 0 zf-RING of BARD1-type protein EphA2_TM PF14575.1 EGC34999.1 - 0.43 10.9 1.9 0.94 9.9 0.1 2.1 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain Ly49 PF08391.5 EGC34999.1 - 1.5 8.9 5.7 0.6 10.2 0.5 2.2 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region OppC_N PF12911.2 EGC34999.1 - 2.4 7.6 6.2 0.15 11.4 0.5 1.8 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DZR PF12773.2 EGC34999.1 - 2.7 7.8 8.6 35 4.3 6.0 2.2 1 1 1 2 2 2 0 Double zinc ribbon Bap31 PF05529.7 EGC34999.1 - 7.9 5.8 8.3 1.9 7.9 0.9 2.0 1 1 0 2 2 2 0 B-cell receptor-associated protein 31-like TIG PF01833.19 EGC35001.1 - 4.4e-115 375.9 135.5 7.7e-12 45.0 0.5 18.4 16 1 1 17 17 17 14 IPT/TIG domain DNase_II PF03265.10 EGC35002.1 - 3.6e-42 144.5 11.9 7.6e-36 123.7 5.0 2.1 2 0 0 2 2 2 2 Deoxyribonuclease II TrwC PF08751.6 EGC35002.1 - 0.032 13.6 0.2 0.048 13.0 0.1 1.2 1 0 0 1 1 1 0 TrwC relaxase Snf7 PF03357.16 EGC35003.1 - 1.3e-23 83.2 15.4 1.3e-23 83.2 10.7 1.3 2 0 0 2 2 2 1 Snf7 Ist1 PF03398.9 EGC35003.1 - 1.1e-05 24.9 5.2 1.7e-05 24.3 3.6 1.3 1 0 0 1 1 1 1 Regulator of Vps4 activity in the MVB pathway Hpt PF01627.18 EGC35003.1 - 0.18 11.8 1.1 0.93 9.5 0.0 2.6 3 1 0 3 3 3 0 Hpt domain DUF3385 PF11865.3 EGC35003.1 - 0.24 11.3 2.8 0.4 10.5 1.9 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3385) YlqD PF11068.3 EGC35003.1 - 0.25 11.3 16.9 0.55 10.2 4.3 2.6 1 1 0 2 2 2 0 YlqD protein zf-RING_2 PF13639.1 EGC35004.1 - 1.3e-09 37.7 9.5 3.4e-09 36.3 6.6 1.8 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC35004.1 - 7.4e-07 28.7 13.7 7.4e-07 28.7 9.5 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC35004.1 - 2.1e-06 27.3 7.3 4.3e-06 26.2 5.1 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC35004.1 - 7.6e-06 25.9 6.3 3.2e-05 23.9 4.3 2.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC35004.1 - 9.9e-06 25.4 12.6 2.2e-05 24.3 8.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC35004.1 - 0.0068 16.2 10.3 0.02 14.7 7.1 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC35004.1 - 0.013 15.0 9.0 0.029 13.9 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGC35004.1 - 0.015 15.0 11.0 0.038 13.7 7.6 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGC35004.1 - 0.12 12.2 5.6 0.61 9.9 3.9 2.2 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger C1_4 PF07975.7 EGC35004.1 - 0.78 9.7 8.2 2.8 8.0 5.7 2.1 1 1 0 1 1 1 0 TFIIH C1-like domain P12 PF12669.2 EGC35008.1 - 0.17 12.1 2.7 0.34 11.1 1.9 1.5 1 0 0 1 1 1 0 Virus attachment protein p12 family Brr6_like_C_C PF10104.4 EGC35009.1 - 7.7e-08 31.9 0.4 1.4e-07 31.0 0.3 1.4 1 0 0 1 1 1 1 Di-sulfide bridge nucleocytoplasmic transport domain DUF747 PF05346.6 EGC35009.1 - 0.0057 15.7 0.8 0.0081 15.2 0.5 1.2 1 0 0 1 1 1 1 Eukaryotic membrane protein family Secretin_N_2 PF07655.8 EGC35009.1 - 0.016 15.5 9.4 0.024 15.0 6.5 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC35009.1 - 0.16 12.0 9.7 0.4 10.7 6.7 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) ABC2_membrane_3 PF12698.2 EGC35009.1 - 0.81 8.6 5.8 1.2 8.1 4.0 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein DUF2971 PF11185.3 EGC35009.1 - 2.1 9.1 6.5 4.1 8.2 4.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2971) Apis_Csd PF11671.3 EGC35009.1 - 2.5 7.8 18.0 5.8 6.7 12.5 1.6 1 0 0 1 1 1 0 Complementary sex determiner protein Corona_M PF01635.13 EGC35009.1 - 8.4 5.2 7.4 1.3 7.9 0.2 2.1 2 0 0 2 2 2 0 Coronavirus M matrix/glycoprotein EcoR124_C PF12008.3 EGC35010.1 - 0.0013 17.9 3.7 0.002 17.3 2.5 1.3 1 0 0 1 1 1 1 Type I restriction and modification enzyme - subunit R C terminal CH PF00307.26 EGC35011.1 - 6e-43 145.2 7.1 6e-24 84.1 0.0 4.5 4 1 0 4 4 4 2 Calponin homology (CH) domain Spectrin PF00435.16 EGC35011.1 - 4.6e-32 110.4 27.9 1.2e-09 38.3 0.7 4.6 4 0 0 4 4 4 4 Spectrin repeat EFhand_Ca_insen PF08726.5 EGC35011.1 - 2.1e-15 56.4 1.0 7.2e-15 54.7 0.3 2.3 2 0 0 2 2 2 1 Ca2+ insensitive EF hand CAMSAP_CH PF11971.3 EGC35011.1 - 2.5e-14 52.6 0.1 4.8e-12 45.3 0.0 2.9 2 0 0 2 2 2 1 CAMSAP CH domain EF-hand_6 PF13405.1 EGC35011.1 - 2e-11 42.7 0.8 0.00022 20.8 0.1 4.2 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGC35011.1 - 2.3e-11 42.1 3.2 7.3e-06 24.9 0.0 3.3 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGC35011.1 - 9.2e-11 41.7 3.1 9.6e-10 38.4 0.7 3.4 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_8 PF13833.1 EGC35011.1 - 8.8e-10 38.0 1.8 8e-08 31.7 0.2 3.0 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC35011.1 - 1.7e-06 27.0 6.1 0.0011 18.1 0.0 3.9 4 0 0 4 4 4 2 EF hand EF-hand_4 PF12763.2 EGC35011.1 - 0.0076 15.9 0.1 0.063 13.0 0.1 2.7 1 0 0 1 1 1 1 Cytoskeletal-regulatory complex EF hand CTK3_C PF12350.3 EGC35011.1 - 0.0083 16.1 0.3 0.64 10.0 0.0 3.9 2 0 0 2 2 2 1 CTD kinase subunit gamma CTK3 C-terminus Phage_CRI PF05144.9 EGC35012.1 - 0.16 11.0 0.7 0.18 10.9 0.5 1.3 1 1 0 1 1 1 0 Phage replication protein CRI Coiled PF05710.7 EGC35012.1 - 1.6 9.2 16.6 6.7 7.2 11.5 1.9 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC35013.1 - 0.0012 19.3 9.3 0.0017 18.7 6.4 1.4 1 1 0 1 1 1 1 Coiled coil EMP70 PF02990.11 EGC35014.1 - 1.5e-32 112.8 53.4 3.9e-17 61.9 7.0 3.1 3 0 0 3 3 3 3 Endomembrane protein 70 DUF1049 PF06305.6 EGC35014.1 - 0.069 12.6 0.5 0.49 9.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF1183 PF06682.7 EGC35014.1 - 5.2 6.5 8.7 0.11 12.0 0.7 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1183) UbiA PF01040.13 EGC35015.1 - 1.7e-15 56.9 17.8 2.6e-15 56.3 12.3 1.4 1 1 0 1 1 1 1 UbiA prenyltransferase family Caveolin PF01146.12 EGC35015.1 - 1.1 8.7 7.2 0.82 9.2 2.0 2.3 2 0 0 2 2 2 0 Caveolin Cation_efflux PF01545.16 EGC35016.1 - 9.9e-64 215.1 6.8 1.3e-63 214.7 4.7 1.1 1 0 0 1 1 1 1 Cation efflux family PapD-like PF14874.1 EGC35017.1 - 0.00092 19.1 0.3 12 5.8 0.0 5.5 5 0 0 5 5 5 2 Flagellar-associated PapD-like RRM_5 PF13893.1 EGC35018.1 - 3.6e-17 61.9 4.8 1.2e-08 34.6 0.5 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC35018.1 - 1.2e-14 53.6 2.3 3.8e-08 32.8 0.1 2.9 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35018.1 - 4e-12 45.9 1.7 3.8e-05 23.5 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC35018.1 - 5.1e-09 35.7 0.3 3.7e-05 23.4 0.0 2.6 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif SynMuv_product PF06047.6 EGC35019.1 - 8.2e-49 163.7 1.9 8.2e-49 163.7 1.3 3.4 3 0 0 3 3 3 1 Ras-induced vulval development antagonist Mucin PF01456.12 EGC35019.1 - 0.21 11.3 6.7 0.36 10.6 4.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein zf-FCS PF06467.9 EGC35020.1 - 0.17 11.5 1.7 0.29 10.8 1.2 1.5 1 0 0 1 1 1 0 MYM-type Zinc finger with FCS sequence motif DUF3330 PF11809.3 EGC35020.1 - 0.23 11.3 1.6 0.56 10.1 1.1 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF3330) DUF3446 PF11928.3 EGC35020.1 - 5.9 7.1 18.1 1.2 9.3 3.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) Cornichon PF03311.9 EGC35021.1 - 7.9e-36 123.0 16.2 9.1e-36 122.8 11.2 1.0 1 0 0 1 1 1 1 Cornichon protein CTP_transf_1 PF01148.15 EGC35021.1 - 2.9 7.4 13.5 3.7 7.1 9.4 1.1 1 0 0 1 1 1 0 Cytidylyltransferase family ATP_synt_H PF05493.8 EGC35021.1 - 3.5 7.7 11.6 0.45 10.6 4.1 2.4 2 1 0 2 2 2 0 ATP synthase subunit H Tetraspannin PF00335.15 EGC35021.1 - 3.7 6.7 13.6 0.82 8.9 0.3 2.2 2 0 0 2 2 2 0 Tetraspanin family Arm PF00514.18 EGC35022.1 - 1.4e-40 135.7 0.8 3.6e-14 51.9 0.0 5.9 6 0 0 6 6 6 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC35022.1 - 1.2e-13 51.1 0.0 5.6e-08 32.9 0.0 4.8 3 1 2 5 5 5 4 HEAT repeats HEAT_EZ PF13513.1 EGC35022.1 - 2.3e-13 50.1 0.0 1.2e-07 32.0 0.0 4.2 3 1 0 3 3 3 2 HEAT-like repeat HEAT PF02985.17 EGC35022.1 - 7.8e-09 34.8 6.2 0.00058 19.7 0.0 5.4 5 0 0 5 5 5 2 HEAT repeat Atx10homo_assoc PF09759.4 EGC35022.1 - 6.1 6.6 9.2 1.6 8.5 0.1 3.7 3 2 1 4 4 4 0 Spinocerebellar ataxia type 10 protein domain RCC1 PF00415.13 EGC35023.1 - 1.9e-64 213.6 20.3 4e-14 52.5 0.1 8.2 8 1 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RasGAP PF00616.14 EGC35023.1 - 1.5e-47 161.8 0.0 1.5e-47 161.8 0.0 4.3 4 2 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase RCC1_2 PF13540.1 EGC35023.1 - 4.2e-35 118.6 26.7 4.6e-08 32.4 0.0 7.6 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RhoGEF PF00621.15 EGC35023.1 - 2.6e-26 92.6 2.5 2.6e-26 92.6 1.7 2.7 2 0 0 2 2 2 1 RhoGEF domain CAF-1_p150 PF11600.3 EGC35023.1 - 3.5e-05 23.2 42.0 3.5e-05 23.2 29.1 5.2 5 1 1 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal MMR_HSR1 PF01926.18 EGC35024.1 - 1.3e-18 67.0 0.0 4e-18 65.4 0.0 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC35024.1 - 1.8e-06 27.3 0.0 3.3e-06 26.4 0.0 1.5 1 0 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGC35024.1 - 7.7e-06 25.4 0.1 0.0028 17.1 0.1 2.7 2 1 0 2 2 2 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGC35024.1 - 4.8e-05 23.2 13.6 0.00029 20.6 0.0 4.1 3 1 1 4 4 4 2 Dynamin family DUF258 PF03193.11 EGC35024.1 - 0.00024 20.3 0.0 0.00061 19.0 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGC35024.1 - 0.00057 19.0 0.9 0.0018 17.3 0.6 1.9 1 1 0 1 1 1 1 AIG1 family PduV-EutP PF10662.4 EGC35024.1 - 0.016 14.6 0.0 0.37 10.2 0.0 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EGC35024.1 - 0.029 13.8 0.0 0.062 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Miro PF08477.8 EGC35024.1 - 0.049 14.1 0.2 0.17 12.3 0.0 2.2 2 1 0 2 2 2 0 Miro-like protein ABC_tran PF00005.22 EGC35024.1 - 0.057 13.7 0.0 0.057 13.7 0.0 2.6 3 0 0 3 3 3 0 ABC transporter PDEase_I PF00233.14 EGC35025.1 - 8.6e-61 205.7 8.4 1.2e-60 205.2 5.8 1.2 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase NAP PF00956.13 EGC35026.1 - 6.7e-64 215.3 2.1 6.7e-64 215.3 1.4 1.4 2 0 0 2 2 2 1 Nucleosome assembly protein (NAP) Mst1_SARAH PF11629.3 EGC35026.1 - 0.00049 19.8 1.7 0.0013 18.4 1.2 1.7 1 0 0 1 1 1 1 C terminal SARAH domain of Mst1 NuA4 PF09340.5 EGC35026.1 - 0.023 14.3 0.4 0.05 13.2 0.2 1.6 1 0 0 1 1 1 0 Histone acetyltransferase subunit NuA4 FNIP PF05725.7 EGC35027.1 - 3.2e-109 356.6 72.7 7.5e-15 54.6 0.2 11.4 6 3 5 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 EGC35027.1 - 1.9e-06 27.6 29.1 0.42 10.6 0.0 10.0 3 2 9 12 12 12 5 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC35028.1 - 6.8e-21 73.9 15.0 1.1e-06 28.5 0.1 7.7 6 3 2 8 8 8 5 FNIP Repeat LRR_4 PF12799.2 EGC35028.1 - 0.088 12.4 8.7 5.3 6.7 0.0 3.9 3 2 1 4 4 4 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC35028.1 - 0.26 11.0 2.9 4.1 7.2 0.1 3.0 3 0 0 3 3 3 0 Leucine rich repeat Dak1 PF02733.12 EGC35029.1 - 6.1e-87 291.2 1.5 4.4e-86 288.4 1.0 1.9 1 1 0 1 1 1 1 Dak1 domain Dak2 PF02734.12 EGC35029.1 - 3.8e-47 160.2 0.0 6.1e-47 159.5 0.0 1.3 1 0 0 1 1 1 1 DAK2 domain UBN2 PF14223.1 EGC35029.1 - 0.028 14.1 0.6 0.15 11.8 0.1 2.4 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type SUI1 PF01253.17 EGC35029.1 - 0.045 13.5 0.1 1.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Translation initiation factor SUI1 DUF433 PF04255.9 EGC35029.1 - 0.14 11.5 0.0 0.67 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF433) Proteasome PF00227.21 EGC35031.1 - 1.5e-22 79.8 0.0 3.2e-22 78.7 0.0 1.5 1 1 0 1 1 1 1 Proteasome subunit Pkinase_Tyr PF07714.12 EGC35032.1 - 2e-57 194.2 0.0 3.6e-57 193.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35032.1 - 4e-57 193.3 0.0 8e-57 192.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain RasGEF PF00617.14 EGC35032.1 - 2.1e-46 158.0 0.1 5.6e-46 156.6 0.1 1.8 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC35032.1 - 2.5e-20 72.5 2.0 2.5e-20 72.5 1.4 2.8 3 0 0 3 3 3 1 RasGEF N-terminal motif Kdo PF06293.9 EGC35032.1 - 0.029 13.4 0.0 0.061 12.3 0.0 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC35032.1 - 0.042 13.5 0.0 0.098 12.3 0.0 1.5 2 0 0 2 2 2 0 Phosphotransferase enzyme family FNIP PF05725.7 EGC35033.1 - 9.2e-20 70.3 58.4 5e-12 45.5 1.6 11.1 7 4 4 12 12 12 8 FNIP Repeat LRR_7 PF13504.1 EGC35033.1 - 1.5 9.3 10.0 15 6.3 0.5 6.6 7 0 0 7 7 7 0 Leucine rich repeat HMA PF00403.21 EGC35034.1 - 0.0041 17.2 0.2 0.0099 16.0 0.1 1.7 1 1 0 1 1 1 1 Heavy-metal-associated domain Arm PF00514.18 EGC35034.1 - 0.037 13.8 0.0 0.14 12.0 0.0 2.1 1 0 0 1 1 1 0 Armadillo/beta-catenin-like repeat Claudin_2 PF13903.1 EGC35035.1 - 0.00041 20.0 9.2 0.00041 20.0 6.4 2.6 1 1 2 3 3 3 1 PMP-22/EMP/MP20/Claudin tight junction L_HGMIC_fpl PF10242.4 EGC35035.1 - 0.00051 20.0 2.9 0.00078 19.4 2.0 1.3 1 0 0 1 1 1 1 Lipoma HMGIC fusion partner-like protein Amastin PF07344.6 EGC35035.1 - 0.0011 18.5 8.2 0.0031 17.1 4.8 2.5 1 1 1 2 2 2 1 Amastin surface glycoprotein PMP22_Claudin PF00822.15 EGC35035.1 - 0.017 14.7 8.5 0.01 15.4 3.4 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Thioredoxin PF00085.15 EGC35037.1 - 2.1e-13 49.8 0.4 2.5e-13 49.6 0.3 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_7 PF13899.1 EGC35037.1 - 0.0019 18.2 0.1 0.0027 17.6 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_8 PF13905.1 EGC35037.1 - 0.0021 18.1 2.3 0.0095 16.0 1.6 2.0 1 1 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC35037.1 - 0.0034 17.5 1.2 0.036 14.2 0.8 2.1 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EGC35037.1 - 0.12 12.1 0.1 0.17 11.7 0.1 1.4 1 0 0 1 1 1 0 Thioredoxin domain UPF0197 PF05251.7 EGC35038.1 - 1.6e-18 66.7 4.5 1.7e-18 66.6 3.1 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0197) CAAD PF14159.1 EGC35038.1 - 0.018 14.6 0.3 0.027 14.1 0.2 1.3 1 1 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF1212 PF06738.7 EGC35038.1 - 0.72 9.2 3.2 0.9 8.9 2.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1212) RII_binding_1 PF10522.4 EGC35039.1 - 0.089 12.9 0.2 0.34 11.1 0.1 2.1 2 0 0 2 2 2 0 RII binding domain zf-met PF12874.2 EGC35039.1 - 0.11 12.7 0.7 0.42 10.8 0.5 2.1 1 0 0 1 1 1 0 Zinc-finger of C2H2 type RhoGAP PF00620.22 EGC35040.1 - 7.1e-23 80.9 2.1 1.4e-22 79.9 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain Ribonuc_L-PSP PF01042.16 EGC35040.1 - 0.14 11.9 0.5 15 5.3 0.1 2.5 2 0 0 2 2 2 0 Endoribonuclease L-PSP AMA-1 PF02430.10 EGC35041.1 - 0.0092 14.9 3.6 0.012 14.4 2.5 1.1 1 0 0 1 1 1 1 Apical membrane antigen 1 MSC PF09402.5 EGC35041.1 - 0.084 11.5 5.3 0.46 9.1 3.7 2.0 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Vpu PF00558.14 EGC35041.1 - 0.19 11.3 1.4 0.34 10.4 1.0 1.4 1 0 0 1 1 1 0 Vpu protein DUF2681 PF10883.3 EGC35041.1 - 0.25 11.5 0.1 0.25 11.5 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) SieB PF14163.1 EGC35042.1 - 0.024 14.2 0.8 0.031 13.8 0.6 1.2 1 0 0 1 1 1 0 Superinfection exclusion protein B COPI_assoc PF08507.5 EGC35042.1 - 0.042 13.5 1.8 0.058 13.0 0.5 1.7 1 1 1 2 2 2 0 COPI associated protein zf-C2H2 PF00096.21 EGC35043.1 - 3.7e-11 42.6 21.5 0.00013 22.1 2.9 3.9 3 0 0 3 3 3 3 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGC35043.1 - 0.0019 18.3 10.6 0.013 15.7 0.7 4.5 4 0 0 4 4 4 2 C2H2-type zinc finger zf-BED PF02892.10 EGC35043.1 - 0.0073 16.0 2.4 0.0073 16.0 1.7 4.0 4 0 0 4 4 4 1 BED zinc finger zf-C2H2_jaz PF12171.3 EGC35043.1 - 0.0074 16.3 3.5 0.0074 16.3 2.4 3.7 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-H2C2_2 PF13465.1 EGC35043.1 - 0.018 15.3 2.3 0.018 15.3 1.6 5.2 4 1 0 4 4 4 0 Zinc-finger double domain zf-met PF12874.2 EGC35043.1 - 0.018 15.2 2.3 0.018 15.2 1.6 3.6 4 0 0 4 4 4 0 Zinc-finger of C2H2 type zf-C2H2_6 PF13912.1 EGC35043.1 - 0.77 9.7 15.8 0.75 9.7 1.0 3.7 3 0 0 3 3 3 0 C2H2-type zinc finger DNA_alkylation PF08713.6 EGC35044.1 - 2.3e-51 174.3 0.7 2.6e-51 174.1 0.5 1.0 1 0 0 1 1 1 1 DNA alkylation repair enzyme Urotensin_II PF02083.10 EGC35044.1 - 0.045 13.1 0.9 0.13 11.6 0.6 1.8 1 0 0 1 1 1 0 Urotensin II Glyco_hydro_38 PF01074.17 EGC35047.1 - 5.8e-72 242.2 2.1 9.3e-72 241.5 1.5 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC35047.1 - 1.8e-23 82.5 0.3 5.1e-23 81.0 0.2 1.9 1 0 0 1 1 1 1 Alpha mannosidase, middle domain G3P_antiterm PF04309.7 EGC35047.1 - 0.011 14.7 0.0 0.039 12.9 0.0 1.8 2 0 0 2 2 2 0 Glycerol-3-phosphate responsive antiterminator Glyco_hydro_39 PF01229.12 EGC35048.1 - 3.4e-63 213.7 0.6 3.7e-63 213.5 0.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolases family 39 Cellulase PF00150.13 EGC35048.1 - 0.0049 16.1 0.0 0.0052 16.0 0.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) L_HGMIC_fpl PF10242.4 EGC35049.1 - 0.083 12.8 0.5 0.19 11.6 0.0 1.8 2 0 0 2 2 2 0 Lipoma HMGIC fusion partner-like protein BUD22 PF09073.5 EGC35050.1 - 0.0092 15.0 23.2 0.01 14.9 16.1 1.1 1 0 0 1 1 1 1 BUD22 Rep_2 PF01719.12 EGC35050.1 - 0.019 14.4 2.4 0.033 13.6 1.7 1.4 1 1 0 1 1 1 0 Plasmid replication protein Nop14 PF04147.7 EGC35050.1 - 0.12 10.2 32.4 0.17 9.7 22.4 1.3 1 0 0 1 1 1 0 Nop14-like family Raftlin PF15250.1 EGC35050.1 - 0.41 9.1 7.7 0.5 8.8 5.4 1.1 1 0 0 1 1 1 0 Raftlin Paf1 PF03985.8 EGC35050.1 - 0.99 8.0 23.5 1.4 7.6 16.3 1.3 1 0 0 1 1 1 0 Paf1 Astro_capsid PF03115.9 EGC35050.1 - 1.7 6.7 10.0 2.1 6.4 7.0 1.2 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Pilt PF15453.1 EGC35050.1 - 4.5 6.8 10.7 6.1 6.4 7.4 1.2 1 0 0 1 1 1 0 Protein incorporated later into Tight Junctions DUF2201_N PF13203.1 EGC35050.1 - 4.6 6.3 11.5 6.4 5.8 8.0 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF1510 PF07423.6 EGC35050.1 - 5.5 6.2 21.9 8.9 5.6 15.2 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CBM_11 PF03425.8 EGC35051.1 - 0.00036 20.2 0.2 0.00082 19.1 0.1 1.6 1 0 0 1 1 1 1 Carbohydrate binding domain (family 11) DPBB_1 PF03330.13 EGC35051.1 - 0.0011 18.9 0.1 0.0032 17.4 0.0 1.9 1 0 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Barwin PF00967.12 EGC35051.1 - 0.04 13.5 0.0 0.35 10.5 0.0 2.2 2 0 0 2 2 2 0 Barwin family Pollen_allerg_1 PF01357.16 EGC35051.1 - 0.048 13.4 0.3 0.099 12.4 0.2 1.5 1 0 0 1 1 1 0 Pollen allergen Lyase_1 PF00206.15 EGC35052.1 - 2e-53 181.6 0.0 2.6e-53 181.2 0.0 1.1 1 0 0 1 1 1 1 Lyase ASL_C PF08328.6 EGC35052.1 - 5.5e-47 158.3 0.1 2e-46 156.5 0.0 2.0 2 0 0 2 2 2 1 Adenylosuccinate lyase C-terminal Peptidase_M16_C PF05193.16 EGC35053.1 - 3.2e-18 66.0 0.2 1.5e-11 44.3 0.0 3.4 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC35053.1 - 1.5e-08 34.5 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) NOA36 PF06524.7 EGC35053.1 - 0.14 11.4 16.1 0.25 10.5 11.1 1.3 1 0 0 1 1 1 0 NOA36 protein SDA1 PF05285.7 EGC35053.1 - 0.4 9.9 22.5 0.74 9.0 15.6 1.3 1 0 0 1 1 1 0 SDA1 DUF1510 PF07423.6 EGC35053.1 - 0.55 9.5 21.2 1.1 8.5 14.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGC35053.1 - 1.2 7.1 18.2 1.9 6.3 12.6 1.3 1 0 0 1 1 1 0 CDC45-like protein Zip PF02535.17 EGC35053.1 - 1.6 7.6 4.0 2.5 6.9 2.8 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Peptidase_C37 PF05416.7 EGC35053.1 - 2.2 6.5 5.2 3.5 5.8 3.6 1.2 1 0 0 1 1 1 0 Southampton virus-type processing peptidase CobT PF06213.7 EGC35053.1 - 2.2 7.3 24.3 3.6 6.6 16.8 1.3 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Daxx PF03344.10 EGC35053.1 - 2.4 6.5 26.3 4 5.7 18.2 1.2 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EGC35053.1 - 5.1 6.2 15.8 7.8 5.6 10.9 1.2 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Nop14 PF04147.7 EGC35053.1 - 6.1 4.6 33.4 0.3 8.9 19.3 1.5 2 0 0 2 2 2 0 Nop14-like family Astro_capsid PF03115.9 EGC35053.1 - 6.5 4.8 8.4 12 3.9 5.8 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor BUD22 PF09073.5 EGC35053.1 - 9 5.2 29.0 1.3 8.0 13.5 2.2 2 0 0 2 2 2 0 BUD22 Pox_Ag35 PF03286.9 EGC35053.1 - 9.6 5.6 17.5 26 4.2 12.1 1.7 1 0 0 1 1 1 0 Pox virus Ag35 surface protein DUF4507 PF14964.1 EGC35054.1 - 5.1e-08 32.0 2.5 0.0013 17.5 0.3 3.1 2 1 0 2 2 2 2 Domain of unknown function (DUF4507) RPAP3_C PF13877.1 EGC35054.1 - 4 7.4 8.7 3.1 7.8 0.1 4.1 2 2 2 4 4 4 0 Potential Monad-binding region of RPAP3 AMIN PF11741.3 EGC35055.1 - 0.064 13.2 0.8 0.18 11.7 0.6 1.8 1 0 0 1 1 1 0 AMIN domain LRR_8 PF13855.1 EGC35055.1 - 0.34 10.7 7.6 4.4 7.1 0.0 3.7 3 1 0 3 3 3 0 Leucine rich repeat WD40 PF00400.27 EGC35056.1 - 4.1e-40 134.2 7.9 3.4e-10 39.4 0.1 7.1 7 0 0 7 7 7 5 WD domain, G-beta repeat Striatin PF08232.7 EGC35056.1 - 3e-30 105.2 3.0 3e-30 105.2 2.1 4.2 3 1 1 4 4 4 1 Striatin family Methyltransf_23 PF13489.1 EGC35056.1 - 0.063 12.9 0.8 0.15 11.7 0.5 1.6 1 0 0 1 1 1 0 Methyltransferase domain MMPL PF03176.10 EGC35056.1 - 0.79 8.3 4.5 1.2 7.7 3.1 1.4 1 0 0 1 1 1 0 MMPL family DUF4175 PF13779.1 EGC35056.1 - 0.97 7.0 21.2 1.5 6.3 14.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF4140 PF13600.1 EGC35056.1 - 1.4 9.4 13.4 2.4 8.6 5.3 2.7 2 0 0 2 2 2 0 N-terminal domain of unknown function (DUF4140) Methyltransf_12 PF08242.7 EGC35056.1 - 8.7 6.8 7.4 18 5.8 1.0 3.5 3 0 0 3 3 3 0 Methyltransferase domain Lyase_aromatic PF00221.14 EGC35057.1 - 1.9e-180 600.3 0.0 2.2e-180 600.1 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase Soyouz_module PF14313.1 EGC35057.1 - 0.012 15.1 0.1 0.037 13.5 0.1 1.8 2 0 0 2 2 2 0 N-terminal region of Paramyxovirinae phosphoprotein (P) PPR_2 PF13041.1 EGC35059.1 - 3.6e-31 106.8 8.2 1.6e-07 31.1 0.0 6.5 5 2 2 7 7 7 6 PPR repeat family PPR_3 PF13812.1 EGC35059.1 - 5.1e-19 66.8 0.0 0.00024 21.1 0.0 6.7 7 0 0 7 7 7 4 Pentatricopeptide repeat domain PPR PF01535.15 EGC35059.1 - 1.6e-17 62.2 5.8 3.3e-05 23.5 0.0 7.0 7 0 0 7 7 7 4 PPR repeat PPR_1 PF12854.2 EGC35059.1 - 9.3e-09 34.6 5.6 0.015 14.7 0.0 6.2 6 0 0 6 6 6 3 PPR repeat AdoMet_dc PF02675.10 EGC35059.1 - 0.01 15.7 0.0 0.03 14.1 0.0 1.8 1 0 0 1 1 1 0 S-adenosylmethionine decarboxylase SPOB_a PF14689.1 EGC35059.1 - 0.09 12.3 2.1 9.6 5.8 0.1 3.5 4 0 0 4 4 4 0 Sensor_kinase_SpoOB-type, alpha-helical domain TPR_7 PF13176.1 EGC35059.1 - 0.13 12.1 0.0 68 3.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat SH2 PF00017.19 EGC35060.1 - 7.3e-15 54.5 0.0 6.9e-12 44.9 0.0 3.2 2 0 0 2 2 2 2 SH2 domain LRR_6 PF13516.1 EGC35060.1 - 0.004 17.0 10.5 0.19 11.9 1.0 4.5 4 0 0 4 4 4 2 Leucine Rich repeat Cbl_N3 PF02762.9 EGC35060.1 - 0.063 12.9 0.0 1.2 8.7 0.0 2.6 2 0 0 2 2 2 0 CBL proto-oncogene N-terminus, SH2-like domain DUF202 PF02656.10 EGC35061.1 - 2e-10 40.7 4.6 2e-10 40.7 3.2 1.9 2 0 0 2 2 2 1 Domain of unknown function (DUF202) BLVR PF06375.6 EGC35061.1 - 0.011 15.5 19.8 0.011 15.5 13.7 2.3 2 0 0 2 2 2 0 Bovine leukaemia virus receptor (BLVR) P2X_receptor PF00864.14 EGC35062.1 - 7.2e-21 74.3 1.0 1.2e-09 37.3 0.1 2.5 2 1 0 2 2 2 2 ATP P2X receptor Fz PF01392.17 EGC35064.1 - 0.00049 20.4 5.8 0.00078 19.7 4.0 1.3 1 0 0 1 1 1 1 Fz domain GFO_IDH_MocA PF01408.17 EGC35065.1 - 2.8e-25 89.1 0.0 4.1e-25 88.6 0.0 1.3 1 0 0 1 1 1 1 Oxidoreductase family, NAD-binding Rossmann fold GFO_IDH_MocA_C PF02894.12 EGC35065.1 - 9.1e-06 25.4 0.0 2.1e-05 24.2 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase family, C-terminal alpha/beta domain TPT PF03151.11 EGC35066.1 - 2.6e-30 105.0 17.2 2.6e-30 105.0 11.9 2.8 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGC35066.1 - 4.1e-15 55.9 41.9 1.3e-07 31.7 12.5 2.3 2 0 0 2 2 2 2 EamA-like transporter family UAA PF08449.6 EGC35066.1 - 1.8e-11 43.5 33.4 2.5e-11 43.0 23.1 1.2 1 0 0 1 1 1 1 UAA transporter family EmrE PF13536.1 EGC35066.1 - 0.00014 22.0 33.7 0.0068 16.5 6.2 3.8 1 1 3 4 4 4 2 Multidrug resistance efflux transporter UPF0060 PF02694.10 EGC35066.1 - 0.018 15.0 2.2 0.018 15.0 1.5 2.3 3 0 0 3 3 3 0 Uncharacterised BCR, YnfA/UPF0060 family RNA12 PF10443.4 EGC35068.1 - 2.5e-102 342.6 0.6 3e-101 339.0 0.4 2.2 1 1 0 1 1 1 1 RNA12 protein Arch_ATPase PF01637.13 EGC35068.1 - 6.2e-08 32.6 0.6 1.1e-07 31.8 0.0 1.8 2 0 0 2 2 2 1 Archaeal ATPase AAA_23 PF13476.1 EGC35068.1 - 0.00082 19.7 1.7 1.9 8.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain RRM_1 PF00076.17 EGC35068.1 - 0.00095 18.7 0.0 0.011 15.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35068.1 - 0.0014 18.5 0.0 0.0041 17.0 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) AAA_35 PF14516.1 EGC35068.1 - 0.0033 16.1 0.0 0.0069 15.0 0.0 1.6 1 0 0 1 1 1 1 AAA-like domain RRM_5 PF13893.1 EGC35068.1 - 0.0056 16.5 0.0 0.014 15.2 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) AAA_22 PF13401.1 EGC35068.1 - 0.017 15.2 0.0 0.046 13.8 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC35068.1 - 0.022 14.7 0.0 0.21 11.5 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain EGF_CA PF07645.10 EGC35069.1 - 1.9e-22 78.9 40.5 8.4e-09 35.2 5.1 3.4 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 EGC35069.1 - 2.9e-22 78.4 46.2 2.3e-09 37.2 5.6 3.7 4 0 0 4 4 4 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EGC35069.1 - 8.5e-15 54.0 29.0 1.6e-07 30.8 0.8 5.1 5 0 0 5 5 5 4 Complement Clr-like EGF-like EGF_3 PF12947.2 EGC35069.1 - 2.1e-07 30.7 29.5 0.00047 20.0 1.6 3.7 3 1 0 3 3 3 3 EGF domain EGF PF00008.22 EGC35069.1 - 1.5e-06 28.0 33.1 0.0045 16.9 4.2 3.5 3 0 0 3 3 3 3 EGF-like domain EGF_MSP1_1 PF12946.2 EGC35069.1 - 0.0013 18.4 18.5 0.014 15.1 0.3 3.6 3 0 0 3 3 3 2 MSP1 EGF domain 1 hEGF PF12661.2 EGC35069.1 - 1.8 8.8 17.1 0.38 10.9 0.5 3.2 3 0 0 3 3 3 0 Human growth factor-like EGF IKI3 PF04762.7 EGC35070.1 - 9.2e-268 890.8 1.8 1.6e-267 890.0 1.3 1.4 1 0 0 1 1 1 1 IKI3 family Apc4_WD40 PF12894.2 EGC35070.1 - 0.00069 19.0 0.3 0.075 12.5 0.0 3.8 4 0 0 4 4 4 1 Anaphase-promoting complex subunit 4 WD40 domain WD40 PF00400.27 EGC35070.1 - 0.081 12.8 2.7 2.6 8.0 0.0 4.2 5 0 0 5 5 5 0 WD domain, G-beta repeat rve_2 PF13333.1 EGC35071.1 - 0.59 10.2 4.4 3 8.0 0.0 3.6 4 0 0 4 4 4 0 Integrase core domain adh_short PF00106.20 EGC35072.1 - 4e-23 82.1 0.0 5.7e-23 81.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC35072.1 - 2.3e-11 43.9 0.0 3.1e-11 43.5 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC35072.1 - 1.2e-07 31.6 0.0 3.1e-07 30.2 0.0 1.5 1 1 0 1 1 1 1 KR domain Saccharop_dh PF03435.13 EGC35072.1 - 0.0026 16.7 0.0 0.0041 16.1 0.0 1.3 1 0 0 1 1 1 1 Saccharopine dehydrogenase Epimerase PF01370.16 EGC35072.1 - 0.0064 15.9 0.0 0.01 15.2 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC35072.1 - 0.013 15.4 0.0 0.023 14.7 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding Eno-Rase_NADH_b PF12242.3 EGC35072.1 - 0.1 12.4 0.2 0.31 10.8 0.0 1.8 2 0 0 2 2 2 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase NmrA PF05368.8 EGC35072.1 - 0.12 11.5 0.0 0.18 10.9 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Neurochondrin PF05536.6 EGC35073.1 - 2e-39 135.3 0.3 1e-18 67.0 0.0 3.5 2 1 0 2 2 2 2 Neurochondrin RIX1 PF08167.7 EGC35073.1 - 0.00056 19.6 0.1 0.0024 17.5 0.0 2.1 1 0 0 1 1 1 1 rRNA processing/ribosome biogenesis MFS_1 PF07690.11 EGC35074.1 - 6.9e-39 133.5 35.3 1.1e-32 113.1 14.8 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC35074.1 - 5.2e-13 48.3 6.8 5.2e-13 48.3 4.7 2.5 1 1 1 2 2 2 1 Sugar (and other) transporter DUF2719 PF10891.3 EGC35075.1 - 0.0046 16.6 0.9 0.013 15.1 0.6 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF2719) DNA_pol_B_palm PF14792.1 EGC35076.1 - 2.8e-36 123.9 0.0 8.9e-36 122.3 0.0 1.9 1 0 0 1 1 1 1 DNA polymerase beta palm DNA_pol_B_thumb PF14791.1 EGC35076.1 - 4.1e-21 74.4 0.1 2.3e-20 72.0 0.0 2.3 3 0 0 3 3 3 1 DNA polymerase beta thumb HHH_8 PF14716.1 EGC35076.1 - 2.6e-19 69.1 1.1 1.7e-17 63.3 0.2 2.6 2 0 0 2 2 2 1 Helix-hairpin-helix domain DNA_pol_lambd_f PF10391.4 EGC35076.1 - 1.3e-18 66.3 1.6 3.2e-18 65.0 0.0 2.5 3 0 0 3 3 3 1 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EGC35076.1 - 1.9e-07 31.1 1.7 1.5e-05 25.0 0.0 2.6 1 1 0 2 2 2 1 Helix-hairpin-helix domain NTP_transf_2 PF01909.18 EGC35076.1 - 0.00034 20.8 0.2 0.00096 19.4 0.1 1.9 1 1 0 1 1 1 1 Nucleotidyltransferase domain DUF4332 PF14229.1 EGC35076.1 - 0.00077 19.4 0.0 0.0017 18.3 0.0 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) HHH_3 PF12836.2 EGC35076.1 - 0.0023 17.8 0.1 0.19 11.6 0.0 3.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif HHH PF00633.18 EGC35076.1 - 0.0035 16.9 1.8 2.8 7.8 0.0 3.0 3 0 0 3 3 3 2 Helix-hairpin-helix motif TBX PF12598.3 EGC35076.1 - 0.0043 17.4 0.6 0.0094 16.3 0.4 1.6 1 0 0 1 1 1 1 T-box transcription factor Cdd1 PF11731.3 EGC35076.1 - 0.0058 16.5 0.9 0.11 12.4 0.6 2.4 1 1 0 1 1 1 1 Pathogenicity locus HPD PF05044.7 EGC35076.1 - 0.007 16.0 0.1 0.2 11.2 0.0 2.4 2 0 0 2 2 2 1 Homeo-prospero domain HHH_2 PF12826.2 EGC35076.1 - 0.057 13.3 0.0 5.4 6.9 0.0 2.5 1 1 1 2 2 2 0 Helix-hairpin-helix motif Complex1_LYR PF05347.10 EGC35077.1 - 0.066 13.0 0.7 0.11 12.2 0.5 1.4 1 0 0 1 1 1 0 Complex 1 protein (LYR family) YxiJ PF14176.1 EGC35077.1 - 0.08 13.0 1.9 0.3 11.2 0.1 2.0 1 1 1 2 2 2 0 YxiJ-like protein CEP170_C PF15308.1 EGC35077.1 - 0.19 9.9 0.8 0.23 9.6 0.5 1.0 1 0 0 1 1 1 0 CEP170 C-terminus DUF2977 PF11192.3 EGC35077.1 - 0.49 10.2 2.2 0.45 10.3 0.5 1.9 2 1 0 2 2 2 0 Protein of unknown function (DUF2977) EXOSC1 PF10447.4 EGC35078.1 - 4.3e-26 90.6 1.4 8.6e-26 89.7 1.0 1.5 1 0 0 1 1 1 1 Exosome component EXOSC1/CSL4 ECR1_N PF14382.1 EGC35078.1 - 1.9e-15 55.8 0.2 3.8e-15 54.8 0.1 1.6 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region S1 PF00575.18 EGC35078.1 - 0.05 13.6 0.7 0.84 9.7 0.2 2.5 2 1 0 2 2 2 0 S1 RNA binding domain WD40 PF00400.27 EGC35079.1 - 4e-09 36.0 1.1 0.00017 21.3 0.0 3.4 3 0 0 3 3 3 2 WD domain, G-beta repeat CNH PF00780.17 EGC35079.1 - 0.00049 19.5 0.2 0.41 10.0 0.0 2.6 2 1 0 2 2 2 2 CNH domain Coiled PF05710.7 EGC35080.1 - 0.94 9.9 5.7 0.99 9.9 4.0 1.1 1 0 0 1 1 1 0 Coiled coil RRM_1 PF00076.17 EGC35081.1 - 3.6e-20 71.3 0.2 4.9e-20 70.9 0.1 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35081.1 - 7.2e-14 51.5 0.0 1e-13 51.0 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35081.1 - 3e-10 39.7 0.2 4.4e-10 39.2 0.2 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MutL_C PF08676.6 EGC35083.1 - 4.6e-28 97.6 0.0 1.1e-27 96.3 0.0 1.7 1 0 0 1 1 1 1 MutL C terminal dimerisation domain DNA_mis_repair PF01119.14 EGC35083.1 - 6.9e-24 83.5 0.0 1.5e-22 79.3 0.0 2.7 1 1 0 1 1 1 1 DNA mismatch repair protein, C-terminal domain HATPase_c_3 PF13589.1 EGC35083.1 - 7.7e-13 48.2 0.0 7.7e-13 48.2 0.0 3.2 3 1 0 3 3 3 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC35083.1 - 9.6e-11 41.3 0.0 2.2e-10 40.2 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_2 PF13581.1 EGC35083.1 - 0.11 12.2 0.0 0.24 11.1 0.0 1.5 1 0 0 1 1 1 0 Histidine kinase-like ATPase domain E1-E2_ATPase PF00122.15 EGC35084.1 - 3.9e-53 179.8 1.8 3.9e-53 179.8 1.2 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGC35084.1 - 4.9e-51 174.1 0.1 9.3e-51 173.2 0.1 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HMA PF00403.21 EGC35084.1 - 4.1e-25 87.6 1.4 3.4e-13 49.5 0.1 3.0 3 0 0 3 3 3 2 Heavy-metal-associated domain HAD PF12710.2 EGC35084.1 - 2.5e-12 47.3 0.0 9e-12 45.5 0.0 2.0 2 1 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_3 PF08282.7 EGC35084.1 - 1.7e-05 24.5 2.2 0.0019 17.8 0.7 2.9 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase Toxin-deaminase PF14424.1 EGC35084.1 - 0.073 13.0 0.8 3.5 7.5 0.0 2.5 2 0 0 2 2 2 0 The BURPS668_1122 family of deaminases RCC1 PF00415.13 EGC35085.1 - 8.3e-70 230.8 5.6 2e-10 40.7 0.0 7.2 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC35085.1 - 1.6e-24 84.9 41.8 1.9e-10 40.0 0.5 8.5 10 0 0 10 10 10 6 Regulator of chromosome condensation (RCC1) repeat Kelch_6 PF13964.1 EGC35085.1 - 0.041 14.0 0.7 0.66 10.2 0.0 3.0 3 0 0 3 3 3 0 Kelch motif Adaptin_N PF01602.15 EGC35086.1 - 1.4e-86 290.9 13.6 2.2e-86 290.3 9.4 1.2 1 0 0 1 1 1 1 Adaptin N terminal region Coatomer_b_Cpla PF14806.1 EGC35086.1 - 3.6e-57 191.6 1.6 7.6e-57 190.6 0.1 2.3 2 0 0 2 2 2 1 Coatomer beta subunit appendage platform Coatamer_beta_C PF07718.7 EGC35086.1 - 1.8e-52 176.7 0.6 4.8e-52 175.3 0.4 1.8 1 0 0 1 1 1 1 Coatomer beta C-terminal region HEAT_2 PF13646.1 EGC35086.1 - 6.6e-09 35.9 0.0 0.00032 20.9 0.0 4.6 2 1 3 5 5 5 3 HEAT repeats HEAT PF02985.17 EGC35086.1 - 9.7e-05 22.1 0.2 10 6.5 0.0 5.3 5 0 0 5 5 5 2 HEAT repeat RhoGEF PF00621.15 EGC35087.1 - 1.7e-54 184.4 4.9 1.7e-54 184.4 3.4 2.2 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EGC35087.1 - 5.6e-06 26.4 0.3 5.6e-06 26.4 0.2 3.4 3 1 0 3 3 3 1 PH domain IQ PF00612.22 EGC35087.1 - 3.5e-05 23.0 0.4 7.7e-05 21.9 0.3 1.6 1 0 0 1 1 1 1 IQ calmodulin-binding motif Integrase_Zn PF02022.14 EGC35087.1 - 0.1 12.0 0.1 0.24 10.8 0.0 1.6 1 0 0 1 1 1 0 Integrase Zinc binding domain Hydrolase_6 PF13344.1 EGC35089.1 - 1.5e-25 89.0 0.0 4e-25 87.6 0.0 1.7 2 0 0 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGC35089.1 - 9.7e-15 54.0 0.0 1.2e-13 50.5 0.0 2.3 3 0 0 3 3 3 1 HAD-hyrolase-like Hydrolase PF00702.21 EGC35089.1 - 7.4e-14 52.6 0.0 9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD_2 PF13419.1 EGC35089.1 - 0.0024 18.1 0.2 2.7 8.1 0.0 3.0 2 1 1 3 3 3 2 Haloacid dehalogenase-like hydrolase Borrelia_REV PF03978.8 EGC35089.1 - 0.03 14.0 0.4 0.073 12.7 0.1 1.8 1 1 0 1 1 1 0 Borrelia burgdorferi REV protein PGP_phosphatase PF09419.5 EGC35089.1 - 0.046 13.0 2.4 7.3 5.9 0.0 2.8 3 0 0 3 3 3 0 Mitochondrial PGP phosphatase Terpene_synth_C PF03936.11 EGC35090.1 - 2.8e-07 30.0 0.0 3.7e-07 29.6 0.0 1.2 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Swi3 PF07962.7 EGC35091.1 - 1.2e-10 40.8 0.0 2.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Replication Fork Protection Component Swi3 Nucleopor_Nup85 PF07575.8 EGC35092.1 - 9.4e-56 189.1 20.0 9.4e-56 189.1 13.8 1.7 2 0 0 2 2 2 1 Nup85 Nucleoporin zf-met PF12874.2 EGC35093.1 - 0.3 11.3 9.5 1.6 9.0 0.4 3.4 3 0 0 3 3 3 0 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGC35093.1 - 1.8 8.7 16.2 0.93 9.7 0.3 3.9 3 1 1 4 4 4 0 Zinc-finger double-stranded RNA-binding FNIP PF05725.7 EGC35094.1 - 1.7e-90 296.7 29.1 1.6e-15 56.7 0.8 7.0 1 1 5 8 8 8 8 FNIP Repeat FNIP PF05725.7 EGC35096.1 - 6.5e-25 86.8 63.2 8.1e-06 25.6 0.3 12.6 10 3 4 14 14 14 9 FNIP Repeat WD40 PF00400.27 EGC35097.1 - 4.8e-16 57.9 0.7 0.58 10.1 0.0 7.7 7 0 0 7 7 7 6 WD domain, G-beta repeat GP40 PF11025.3 EGC35097.1 - 0.034 13.7 0.7 0.091 12.3 0.5 1.7 1 0 0 1 1 1 0 Glycoprotein GP40 of Cryptosporidium DUF1652 PF07865.6 EGC35097.1 - 0.064 12.8 0.2 7.9 6.1 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1652) Macoilin PF09726.4 EGC35098.1 - 2.6 6.2 11.2 4.1 5.5 7.8 1.2 1 0 0 1 1 1 0 Transmembrane protein Zip PF02535.17 EGC35098.1 - 2.6 6.9 7.1 14 4.5 5.3 1.8 2 0 0 2 2 2 0 ZIP Zinc transporter Ank_2 PF12796.2 EGC35099.1 - 6.6e-29 100.0 6.8 3.9e-07 30.3 0.1 5.8 1 1 5 6 6 6 6 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC35099.1 - 3.8e-18 65.4 2.6 0.00024 21.5 0.0 7.4 7 1 2 9 9 9 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC35099.1 - 3.2e-17 62.1 1.3 0.38 11.0 0.0 9.7 3 2 7 10 10 10 5 Ankyrin repeats (many copies) Ank PF00023.25 EGC35099.1 - 3.9e-17 61.0 1.3 0.23 11.3 0.0 9.7 10 0 0 10 10 10 5 Ankyrin repeat Ank_3 PF13606.1 EGC35099.1 - 4e-16 57.5 4.9 2.5 8.5 0.0 10.5 8 2 3 11 11 11 4 Ankyrin repeat DUF249 PF03158.8 EGC35099.1 - 7.4e-05 22.3 7.0 0.47 9.9 0.1 4.4 2 2 1 3 3 3 3 Multigene family 530 protein DUF996 PF06195.8 EGC35100.1 - 0.02 14.8 11.8 0.15 12.0 3.8 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF996) Dicty_spore_N PF04562.7 EGC35101.1 - 1.3e-28 99.6 25.9 1.3e-28 99.6 18.0 4.0 3 1 0 3 3 3 2 Dictyostelium spore coat protein, N terminus DUF377 PF04041.8 EGC35102.1 - 1.3e-22 79.9 0.0 2.5e-22 79.0 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF377) DUF1935 PF09149.5 EGC35102.1 - 0.11 12.5 0.0 0.24 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1935) Brevenin PF03032.10 EGC35102.1 - 0.25 11.2 1.0 0.49 10.2 0.7 1.4 1 0 0 1 1 1 0 Brevenin/esculentin/gaegurin/rugosin family UbiA PF01040.13 EGC35103.1 - 9.2e-21 74.2 9.0 1.1e-20 73.9 6.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family Phage_Gp23 PF10669.4 EGC35104.1 - 0.0061 16.6 0.1 0.014 15.5 0.1 1.5 1 0 0 1 1 1 1 Protein gp23 (Bacteriophage A118) UPF0029 PF01205.14 EGC35105.1 - 1.8e-29 101.5 1.1 3.6e-29 100.6 0.0 1.9 2 0 0 2 2 2 1 Uncharacterized protein family UPF0029 RWD PF05773.17 EGC35105.1 - 5e-19 68.2 1.7 5e-19 68.2 1.2 2.7 2 1 1 3 3 3 1 RWD domain KOG2701 PF09762.4 EGC35105.1 - 0.02 14.9 3.2 0.033 14.2 2.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain-containing protein (DUF2037) HTH_16 PF12645.2 EGC35105.1 - 0.36 10.7 4.0 0.2 11.5 0.3 2.2 2 1 0 2 2 2 0 Helix-turn-helix domain Androgen_recep PF02166.11 EGC35105.1 - 8.3 5.1 7.4 14 4.3 5.1 1.3 1 0 0 1 1 1 0 Androgen receptor Tir_receptor_M PF03549.9 EGC35106.1 - 0.46 10.6 2.3 0.49 10.5 0.3 1.9 2 0 0 2 2 2 0 Translocated intimin receptor (Tir) intimin-binding domain PH_9 PF15410.1 EGC35106.1 - 0.71 10.0 7.0 2.4 8.3 3.2 2.2 2 0 0 2 2 2 0 Pleckstrin homology domain Prp31_C PF09785.4 EGC35106.1 - 2.5 8.5 8.2 3.8 7.9 4.6 2.0 1 1 1 2 2 2 0 Prp31 C terminal domain RNA_pol_3_Rpc31 PF11705.3 EGC35106.1 - 5.7 6.7 9.7 7.9 6.3 6.7 1.1 1 0 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 ABC_membrane PF00664.18 EGC35107.1 - 2.8e-62 210.6 31.4 2.2e-31 109.3 5.1 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC35107.1 - 2.2e-48 164.0 1.5 2.1e-28 99.3 0.0 3.0 3 0 0 3 3 2 2 ABC transporter SMC_N PF02463.14 EGC35107.1 - 1.9e-07 30.5 5.6 0.076 12.2 0.0 4.4 3 1 0 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC35107.1 - 2.4e-06 26.9 1.2 0.031 13.8 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Miro PF08477.8 EGC35107.1 - 8.3e-06 26.3 0.8 0.087 13.3 0.0 3.1 3 0 0 3 3 2 2 Miro-like protein T2SE PF00437.15 EGC35107.1 - 0.002 17.0 0.0 0.8 8.5 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein MMR_HSR1 PF01926.18 EGC35107.1 - 0.0034 17.3 0.3 3.2 7.7 0.0 2.8 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_25 PF13481.1 EGC35107.1 - 0.01 15.2 0.1 2.2 7.6 0.0 3.0 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGC35107.1 - 0.011 14.8 0.4 0.33 10.0 0.1 2.5 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EGC35107.1 - 0.011 16.5 0.3 8.6 7.2 0.0 3.3 3 0 0 3 3 2 0 AAA domain AAA_16 PF13191.1 EGC35107.1 - 0.013 15.4 0.2 1.4 8.9 0.0 2.5 2 0 0 2 2 2 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGC35107.1 - 0.017 14.6 0.1 5.2 6.4 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family cobW PF02492.14 EGC35107.1 - 0.028 13.8 1.0 0.093 12.1 0.0 2.1 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain TrwB_AAD_bind PF10412.4 EGC35107.1 - 0.05 12.2 1.2 2.6 6.5 0.1 2.3 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain DUF87 PF01935.12 EGC35107.1 - 0.05 13.4 0.2 0.05 13.4 0.1 2.7 3 0 0 3 3 2 0 Domain of unknown function DUF87 DUF258 PF03193.11 EGC35107.1 - 0.052 12.7 1.8 0.29 10.3 0.2 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_10 PF12846.2 EGC35107.1 - 0.054 12.9 1.4 2.7 7.3 0.1 3.0 3 0 0 3 3 3 0 AAA-like domain MobB PF03205.9 EGC35107.1 - 0.074 12.7 0.7 11 5.6 0.1 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_22 PF13401.1 EGC35107.1 - 0.11 12.6 3.3 4.2 7.5 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGC35107.1 - 0.12 11.9 0.2 19 4.7 0.0 2.9 2 1 0 2 2 2 0 AAA domain SbcCD_C PF13558.1 EGC35107.1 - 0.17 11.8 0.0 8.2 6.4 0.0 2.7 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit UbiA PF01040.13 EGC35108.1 - 1.1e-32 113.3 10.3 1.3e-32 113.0 7.2 1.1 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4583 PF15190.1 EGC35108.1 - 0.055 13.1 0.6 0.15 11.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4583) tRNA-synt_1c PF00749.16 EGC35109.1 - 2.6e-97 325.2 0.3 2.3e-96 322.1 0.1 2.3 3 0 0 3 3 3 1 tRNA synthetases class I (E and Q), catalytic domain tRNA-synt_1c_C PF03950.13 EGC35109.1 - 1.1e-40 139.1 1.0 2.4e-40 138.0 0.4 1.9 2 0 0 2 2 2 1 tRNA synthetases class I (E and Q), anti-codon binding domain GST_C_3 PF14497.1 EGC35109.1 - 9.1e-08 32.4 0.0 3e-07 30.8 0.0 1.9 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC35109.1 - 1.7e-06 27.9 0.0 4.1e-06 26.6 0.0 1.7 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain ABC2_membrane PF01061.19 EGC35111.1 - 7e-72 240.9 35.9 1.3e-37 129.0 10.4 3.1 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC35111.1 - 4e-43 146.9 0.1 2.5e-22 79.6 0.0 2.4 2 0 0 2 2 2 2 ABC transporter AAA_22 PF13401.1 EGC35111.1 - 1.4e-09 38.1 0.1 0.00048 20.2 0.0 2.8 2 1 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGC35111.1 - 7.7e-08 32.7 0.1 0.011 16.0 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGC35111.1 - 1.5e-07 32.2 0.0 0.0091 16.8 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGC35111.1 - 1.7e-07 30.6 0.3 0.0017 17.8 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC35111.1 - 2.3e-07 30.9 0.0 0.0081 16.1 0.0 2.4 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGC35111.1 - 6.8e-07 28.6 0.1 0.00061 19.0 0.0 2.7 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC35111.1 - 7e-07 29.2 0.0 0.032 14.1 0.0 2.4 2 0 0 2 2 2 2 AAA domain AAA_25 PF13481.1 EGC35111.1 - 3.9e-06 26.3 0.1 0.049 13.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain AAA_21 PF13304.1 EGC35111.1 - 7.2e-06 26.1 6.3 0.026 14.4 0.0 4.9 4 1 0 5 5 4 1 AAA domain PDR_assoc PF08370.6 EGC35111.1 - 0.00012 21.4 1.3 0.16 11.5 0.2 3.0 2 0 0 2 2 2 2 Plant PDR ABC transporter associated NACHT PF05729.7 EGC35111.1 - 0.0002 21.0 0.2 0.062 12.9 0.0 2.5 2 0 0 2 2 2 1 NACHT domain PDR_CDR PF06422.7 EGC35111.1 - 0.00021 20.8 5.4 0.15 11.7 0.1 2.8 2 0 0 2 2 2 2 CDR ABC transporter SMC_N PF02463.14 EGC35111.1 - 0.00023 20.4 0.2 2.6 7.2 0.0 3.6 3 1 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_14 PF13173.1 EGC35111.1 - 0.00034 20.5 0.0 0.72 9.7 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_28 PF13521.1 EGC35111.1 - 0.00043 20.2 0.0 0.41 10.5 0.0 2.4 2 0 0 2 2 2 1 AAA domain cobW PF02492.14 EGC35111.1 - 0.00053 19.4 2.8 0.15 11.5 0.1 2.5 2 0 0 2 2 2 2 CobW/HypB/UreG, nucleotide-binding domain AAA PF00004.24 EGC35111.1 - 0.0006 20.0 0.1 1.7 8.8 0.0 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGC35111.1 - 0.00061 19.9 0.0 1.3 9.1 0.0 2.9 2 0 0 2 2 2 1 RNA helicase MMR_HSR1 PF01926.18 EGC35111.1 - 0.00082 19.3 0.1 0.31 10.9 0.0 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase ABC2_membrane_3 PF12698.2 EGC35111.1 - 0.00097 18.2 15.1 0.00097 18.2 10.5 3.5 3 1 0 3 3 3 1 ABC-2 family transporter protein Arch_ATPase PF01637.13 EGC35111.1 - 0.004 16.8 0.2 1 9.0 0.0 2.8 3 0 0 3 3 2 1 Archaeal ATPase SbcCD_C PF13558.1 EGC35111.1 - 0.0057 16.5 0.0 1.4 8.9 0.0 2.6 2 0 0 2 2 2 1 Putative exonuclease SbcCD, C subunit AAA_10 PF12846.2 EGC35111.1 - 0.0059 16.0 3.1 0.96 8.8 0.0 2.4 2 0 0 2 2 2 2 AAA-like domain Zeta_toxin PF06414.7 EGC35111.1 - 0.007 15.4 0.0 0.77 8.8 0.0 2.2 2 0 0 2 2 2 1 Zeta toxin Rad17 PF03215.10 EGC35111.1 - 0.0088 14.7 0.0 0.54 8.8 0.0 2.4 3 0 0 3 3 2 1 Rad17 cell cycle checkpoint protein UPF0079 PF02367.12 EGC35111.1 - 0.014 15.0 1.8 0.18 11.4 0.2 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_30 PF13604.1 EGC35111.1 - 0.015 14.9 0.4 5.3 6.5 0.1 2.4 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC35111.1 - 0.019 14.5 0.5 2.2 7.7 0.1 2.6 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGC35111.1 - 0.024 13.4 0.5 0.89 8.2 0.0 2.2 2 0 0 2 2 2 0 ArgK protein AAA_19 PF13245.1 EGC35111.1 - 0.024 14.3 0.4 2.5 7.9 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain AAA_23 PF13476.1 EGC35111.1 - 0.038 14.3 1.6 0.23 11.7 0.0 2.7 3 0 0 3 3 2 0 AAA domain DUF815 PF05673.8 EGC35111.1 - 0.064 12.1 0.1 1.3 7.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF815) FtsK_SpoIIIE PF01580.13 EGC35111.1 - 0.11 11.9 0.3 0.8 9.1 0.0 2.1 2 0 0 2 2 2 0 FtsK/SpoIIIE family NB-ARC PF00931.17 EGC35111.1 - 0.11 11.3 2.6 4.8 5.9 0.1 2.3 2 0 0 2 2 2 0 NB-ARC domain AAA_15 PF13175.1 EGC35111.1 - 0.13 11.2 12.1 3.2 6.6 0.3 4.9 3 1 0 5 5 5 0 AAA ATPase domain IstB_IS21 PF01695.12 EGC35111.1 - 0.14 11.5 0.0 20 4.5 0.0 2.7 2 0 0 2 2 2 0 IstB-like ATP binding protein AAA_5 PF07728.9 EGC35111.1 - 0.21 11.3 4.2 10 5.8 0.0 2.9 3 0 0 3 3 2 0 AAA domain (dynein-related subfamily) DUF2075 PF09848.4 EGC35111.1 - 0.24 10.3 0.2 0.51 9.2 0.0 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Mg_chelatase PF01078.16 EGC35111.1 - 0.62 9.1 2.1 2.7 7.1 0.1 2.2 2 0 0 2 2 2 0 Magnesium chelatase, subunit ChlI Glyco_hydro_38 PF01074.17 EGC35112.1 - 2.5e-85 286.0 0.1 4.8e-85 285.1 0.1 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Glyco_hydro_38C PF07748.8 EGC35112.1 - 8e-76 255.6 0.0 1.7e-75 254.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 C-terminal domain Alpha-mann_mid PF09261.6 EGC35112.1 - 9.7e-22 76.9 0.0 3.1e-21 75.3 0.0 1.9 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_57 PF03065.10 EGC35112.1 - 0.0083 15.0 0.0 0.016 14.1 0.0 1.4 1 0 0 1 1 1 1 Glycosyl hydrolase family 57 DUF2207 PF09972.4 EGC35113.1 - 0.0063 15.1 2.4 0.0071 14.9 1.7 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2207) Cation_efflux PF01545.16 EGC35113.1 - 0.015 14.3 3.2 0.021 13.9 2.2 1.2 1 0 0 1 1 1 0 Cation efflux family Erf4 PF10256.4 EGC35113.1 - 0.016 15.0 6.1 0.047 13.5 2.2 2.7 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family DUF898 PF05987.8 EGC35113.1 - 0.09 11.6 3.2 0.11 11.3 2.2 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Claudin_2 PF13903.1 EGC35113.1 - 1.6 8.4 6.2 3.1 7.4 4.3 1.4 1 1 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction DENN PF02141.16 EGC35115.1 - 2.2e-21 76.4 12.7 1.3e-19 70.6 2.7 3.4 2 1 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.13 EGC35115.1 - 7e-09 35.5 0.7 6.6e-08 32.3 0.4 2.6 2 1 0 2 2 2 1 uDENN domain Avl9 PF09794.4 EGC35115.1 - 2.1e-06 26.5 0.5 2.1e-06 26.5 0.4 1.7 2 0 0 2 2 2 1 Transport protein Avl9 SPA PF08616.5 EGC35115.1 - 5.2e-05 22.9 1.2 0.00022 20.8 0.8 2.2 1 0 0 1 1 1 1 Stabilization of polarity axis MMTV_SAg PF01054.12 EGC35115.1 - 0.077 11.8 0.2 0.16 10.8 0.1 1.4 1 0 0 1 1 1 0 Mouse mammary tumour virus superantigen dDENN PF03455.14 EGC35115.1 - 0.09 12.8 3.0 0.21 11.6 2.1 1.6 1 0 0 1 1 1 0 dDENN domain Acetyltransf_4 PF13420.1 EGC35116.1 - 0.021 14.7 0.6 0.045 13.6 0.4 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain WD40 PF00400.27 EGC35117.1 - 2.5e-28 96.9 21.5 1.6e-08 34.0 0.1 7.5 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC35117.1 - 0.004 16.9 0.0 0.06 13.1 0.0 2.8 3 1 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DZR PF12773.2 EGC35117.1 - 0.035 13.9 9.8 0.1 12.4 6.8 1.9 1 0 0 1 1 1 0 Double zinc ribbon zinc_ribbon_2 PF13240.1 EGC35117.1 - 0.066 12.7 8.2 0.089 12.3 2.8 2.7 2 0 0 2 2 2 0 zinc-ribbon domain Ycf1 PF05758.7 EGC35117.1 - 3.8 5.1 41.5 1.1 6.9 8.3 2.4 2 0 0 2 2 2 0 Ycf1 Methyltransf_2 PF00891.13 EGC35118.1 - 6.8e-48 162.9 0.0 8.6e-48 162.6 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase HTH_23 PF13384.1 EGC35118.1 - 0.068 12.8 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Homeodomain-like domain Sigma70_r4_2 PF08281.7 EGC35118.1 - 0.087 12.3 0.1 0.23 10.9 0.0 1.7 2 0 0 2 2 2 0 Sigma-70, region 4 NinB PF05772.7 EGC35118.1 - 0.087 12.4 0.2 0.15 11.6 0.1 1.4 1 0 0 1 1 1 0 NinB protein MAD PF05557.8 EGC35119.1 - 7.5e-47 159.8 97.5 4.6e-34 117.5 1.9 3.3 1 1 1 2 2 2 2 Mitotic checkpoint protein IncA PF04156.9 EGC35119.1 - 0.01 15.4 14.3 0.01 15.4 9.9 7.0 3 1 2 6 6 6 0 IncA protein Methyltransf_23 PF13489.1 EGC35120.1 - 1.4e-15 57.3 0.0 2.9e-15 56.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC35120.1 - 6.5e-15 55.3 0.0 4.8e-14 52.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC35120.1 - 2.3e-14 53.2 0.5 7.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC35120.1 - 2.1e-11 44.1 0.0 2.1e-11 44.1 0.0 3.5 3 1 0 3 3 3 1 Methyltransferase domain MTS PF05175.9 EGC35120.1 - 0.00038 19.8 0.1 0.0014 18.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase small domain Ubie_methyltran PF01209.13 EGC35120.1 - 0.0005 19.2 0.0 0.00081 18.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGC35120.1 - 0.0089 16.5 0.0 0.024 15.2 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Exo_endo_phos PF03372.18 EGC35121.1 - 0.00048 20.1 0.0 0.00065 19.7 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Exo_endo_phos_2 PF14529.1 EGC35121.1 - 0.00057 19.4 0.1 0.0018 17.9 0.1 1.9 1 0 0 1 1 1 1 Endonuclease-reverse transcriptase V-ATPase_H_N PF03224.9 EGC35121.1 - 0.0074 15.4 0.5 0.012 14.7 0.3 1.4 1 0 0 1 1 1 1 V-ATPase subunit H ELFV_dehydrog PF00208.16 EGC35122.1 - 2.9e-53 180.9 0.1 1.8e-51 175.1 0.0 2.2 1 1 1 2 2 2 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase ELFV_dehydrog_N PF02812.13 EGC35122.1 - 6.8e-44 148.6 0.0 1.1e-43 147.9 0.0 1.3 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2-Hacid_dh_C PF02826.14 EGC35122.1 - 0.025 13.7 0.1 0.045 12.8 0.0 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_7 PF13241.1 EGC35122.1 - 0.03 14.5 0.0 0.08 13.2 0.0 1.7 2 0 0 2 2 2 0 Putative NAD(P)-binding AdoHcyase_NAD PF00670.16 EGC35122.1 - 0.059 13.2 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain Bac_GDH PF05088.7 EGC35122.1 - 0.072 10.4 0.0 0.85 6.9 0.0 2.0 2 0 0 2 2 2 0 Bacterial NAD-glutamate dehydrogenase DUF3430 PF11912.3 EGC35123.1 - 6e-19 68.7 23.0 7.1e-19 68.4 15.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC35123.1 - 0.0099 15.9 2.8 0.0099 15.9 1.9 3.1 1 1 1 3 3 3 1 Protein of unknown function (DUF3586) Thoc2 PF11732.3 EGC35123.1 - 0.083 12.6 0.0 0.27 11.0 0.0 1.8 1 0 0 1 1 1 0 Transcription- and export-related complex subunit Glyco_hydro_18 PF00704.23 EGC35124.1 - 1.4e-15 57.6 5.7 2.1e-15 57.0 3.9 1.3 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 B12D PF06522.6 EGC35124.1 - 0.068 12.8 0.0 0.18 11.5 0.0 1.7 1 0 0 1 1 1 0 NADH-ubiquinone reductase complex 1 MLRQ subunit Dynamin_N PF00350.18 EGC35126.1 - 1.4e-39 135.5 0.1 1.4e-39 135.5 0.1 3.5 4 0 0 4 4 4 1 Dynamin family MMR_HSR1 PF01926.18 EGC35126.1 - 4.9e-05 23.2 0.0 0.0009 19.1 0.0 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC35126.1 - 0.022 15.2 0.1 0.13 12.7 0.0 2.5 2 0 0 2 2 2 0 Miro-like protein NPV_P10 PF05531.7 EGC35126.1 - 0.16 12.2 4.6 0.19 11.9 1.1 2.7 2 0 0 2 2 2 0 Nucleopolyhedrovirus P10 protein DUF3636 PF12331.3 EGC35126.1 - 0.5 9.9 4.9 3.1 7.3 0.1 3.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3636) FlaC_arch PF05377.6 EGC35126.1 - 0.75 9.7 7.1 0.97 9.3 0.3 3.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) EGF_2 PF07974.8 EGC35127.1 - 0.0026 17.8 40.1 0.033 14.3 9.8 3.0 2 0 0 2 2 2 2 EGF-like domain TIG PF01833.19 EGC35127.1 - 0.005 16.8 5.7 0.005 16.8 4.0 3.5 3 1 1 4 4 4 1 IPT/TIG domain Laminin_EGF PF00053.19 EGC35127.1 - 1.2 9.1 36.7 0.17 11.8 7.3 3.3 3 1 0 3 3 3 0 Laminin EGF-like (Domains III and V) 7tm_3 PF00003.17 EGC35128.1 - 6.6e-37 127.1 22.0 9.1e-37 126.6 15.3 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC35128.1 - 2.4e-14 52.7 0.7 3.4e-14 52.3 0.5 1.2 1 0 0 1 1 1 1 Basic membrane protein DUF1510 PF07423.6 EGC35128.1 - 0.053 12.8 4.5 0.097 12.0 3.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF2207 PF09972.4 EGC35128.1 - 0.067 11.7 10.0 0.042 12.4 1.4 2.3 2 0 0 2 2 2 0 Predicted membrane protein (DUF2207) DUF872 PF05915.7 EGC35128.1 - 1.9 8.4 6.6 0.56 10.0 0.2 3.1 2 1 1 3 3 3 0 Eukaryotic protein of unknown function (DUF872) DUF4231 PF14015.1 EGC35128.1 - 2.6 8.0 5.5 1.3 9.0 0.0 2.9 3 1 0 3 3 3 0 Protein of unknown function (DUF4231) NOA36 PF06524.7 EGC35128.1 - 4.3 6.4 6.4 6.6 5.8 4.4 1.2 1 0 0 1 1 1 0 NOA36 protein Casc1 PF12366.3 EGC35130.1 - 0.05 13.1 0.0 0.062 12.7 0.0 1.1 1 0 0 1 1 1 0 Cancer susceptibility candidate 1 HTH_30 PF13556.1 EGC35131.1 - 0.15 11.6 0.0 0.29 10.7 0.0 1.4 1 0 0 1 1 1 0 PucR C-terminal helix-turn-helix domain Thioredoxin PF00085.15 EGC35132.1 - 2.2e-30 104.4 1.7 2.5e-22 78.5 0.1 2.3 2 0 0 2 2 2 2 Thioredoxin Thioredoxin_2 PF13098.1 EGC35132.1 - 8.5e-10 38.8 0.3 5.4e-05 23.3 0.1 3.2 2 1 0 2 2 2 2 Thioredoxin-like domain Thioredoxin_6 PF13848.1 EGC35132.1 - 9.2e-05 22.3 6.8 0.019 14.7 0.2 3.5 2 2 2 4 4 4 2 Thioredoxin-like domain Calsequestrin PF01216.12 EGC35132.1 - 0.0011 17.7 0.4 0.62 8.7 0.0 2.1 2 0 0 2 2 2 2 Calsequestrin Glutaredoxin PF00462.19 EGC35132.1 - 0.0031 17.4 0.6 0.68 9.9 0.1 2.6 2 0 0 2 2 2 2 Glutaredoxin DUF836 PF05768.9 EGC35132.1 - 0.094 12.9 0.5 12 6.1 0.1 2.4 2 0 0 2 2 2 0 Glutaredoxin-like domain (DUF836) ECH_C PF13766.1 EGC35133.1 - 4e-28 97.9 0.2 6e-28 97.3 0.1 1.3 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGC35133.1 - 7.9e-22 77.5 0.0 1.3e-21 76.8 0.0 1.6 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DEAD PF00270.24 EGC35134.1 - 1.3e-19 70.2 0.0 3.8e-19 68.8 0.0 1.8 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC35134.1 - 3.6e-14 52.3 0.0 1.3e-13 50.6 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF1998 PF09369.5 EGC35134.1 - 7.9e-05 23.1 0.3 0.00024 21.6 0.2 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1998) Pkinase PF00069.20 EGC35135.1 - 5.4e-13 48.7 0.1 1e-12 47.7 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35135.1 - 1.1e-10 41.0 0.0 2.1e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase HEAT PF02985.17 EGC35135.1 - 6.8e-06 25.7 0.0 0.62 10.2 0.0 3.8 3 0 0 3 3 3 2 HEAT repeat Kinase-like PF14531.1 EGC35135.1 - 0.00042 19.3 0.0 0.0015 17.5 0.0 1.9 2 0 0 2 2 2 1 Kinase-like Adaptin_N PF01602.15 EGC35135.1 - 0.0013 17.1 0.1 0.0048 15.2 0.0 1.8 1 1 1 2 2 2 1 Adaptin N terminal region HEAT_2 PF13646.1 EGC35135.1 - 0.0066 16.6 0.0 0.026 14.7 0.0 2.0 2 1 0 2 2 2 1 HEAT repeats HEAT_EZ PF13513.1 EGC35135.1 - 0.017 15.6 0.0 9.9 6.8 0.0 3.2 2 1 1 3 3 3 0 HEAT-like repeat Cnd1 PF12717.2 EGC35135.1 - 0.068 13.0 4.6 2.2 8.0 0.3 3.6 2 1 2 4 4 4 0 non-SMC mitotic condensation complex subunit 1 Pkinase PF00069.20 EGC35136.1 - 5.3e-71 238.8 0.0 6e-71 238.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35136.1 - 8e-31 107.0 0.0 1.1e-30 106.6 0.0 1.2 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC35136.1 - 0.00069 18.6 0.0 0.03 13.2 0.0 2.2 2 0 0 2 2 2 2 Kinase-like MutS_V PF00488.16 EGC35137.1 - 6e-88 294.2 0.0 9.9e-88 293.4 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC35137.1 - 6.4e-41 140.3 1.9 6.8e-41 140.2 0.5 1.7 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EGC35137.1 - 3e-34 117.4 0.1 7.3e-34 116.1 0.0 1.7 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGC35137.1 - 3.1e-16 59.6 1.4 3.4e-15 56.3 0.0 3.1 3 0 0 3 3 3 1 MutS domain II MutS_IV PF05190.13 EGC35137.1 - 1e-11 44.8 3.8 1.7e-11 44.1 1.0 2.6 2 0 0 2 2 2 1 MutS family domain IV PBP1_TM PF14812.1 EGC35137.1 - 0.019 15.2 7.8 0.047 13.9 5.4 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF4611 PF15387.1 EGC35137.1 - 0.27 11.3 9.4 1.2 9.3 6.5 2.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Nucleoplasmin PF03066.10 EGC35137.1 - 1.4 8.4 9.0 4.1 6.9 6.2 1.7 1 0 0 1 1 1 0 Nucleoplasmin DAO PF01266.19 EGC35138.1 - 3.3e-48 164.4 0.0 3.8e-48 164.2 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase Thi4 PF01946.12 EGC35138.1 - 0.001 18.1 0.0 0.0018 17.4 0.0 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_8 PF13450.1 EGC35138.1 - 0.0016 18.3 0.0 0.0037 17.2 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Mqo PF06039.10 EGC35138.1 - 0.0022 16.2 0.0 0.39 8.8 0.0 2.1 2 0 0 2 2 2 2 Malate:quinone oxidoreductase (Mqo) Pyr_redox_3 PF13738.1 EGC35138.1 - 0.0049 16.9 0.0 0.053 13.5 0.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC35138.1 - 0.015 15.1 0.4 0.24 11.2 0.3 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGC35138.1 - 0.08 11.8 0.0 0.22 10.3 0.0 1.6 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_binding_3 PF01494.14 EGC35138.1 - 0.15 11.0 0.0 0.69 8.8 0.0 1.9 1 1 0 1 1 1 0 FAD binding domain Pkinase PF00069.20 EGC35140.1 - 2.9e-60 203.5 0.0 4.8e-60 202.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35140.1 - 1.3e-57 194.8 0.0 1.8e-57 194.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC35140.1 - 0.00011 21.3 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Muted PF14942.1 EGC35141.1 - 9.5e-17 61.2 12.1 1.2e-16 60.9 8.4 1.0 1 0 0 1 1 1 1 Organelle biogenesis, Muted-like protein DUF1068 PF06364.7 EGC35141.1 - 0.16 11.5 2.9 0.2 11.2 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1068) Elongin_A PF06881.6 EGC35141.1 - 0.23 11.8 8.4 0.95 9.8 4.1 2.2 2 0 0 2 2 2 0 RNA polymerase II transcription factor SIII (Elongin) subunit A DUF4284 PF14112.1 EGC35141.1 - 0.5 10.8 6.8 0.22 12.0 2.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4284) Phe_tRNA-synt_N PF02912.13 EGC35141.1 - 1.1 9.0 5.3 0.51 10.1 1.2 2.1 2 0 0 2 2 2 0 Aminoacyl tRNA synthetase class II, N-terminal domain RP-C_C PF11800.3 EGC35141.1 - 1.4 8.6 8.6 1.8 8.2 6.0 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region DUF745 PF05335.8 EGC35141.1 - 3.6 7.0 7.0 5.3 6.5 4.9 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF745) SPX PF03105.14 EGC35141.1 - 6.6 6.4 15.1 8.4 6.0 10.5 1.1 1 0 0 1 1 1 0 SPX domain ADH_zinc_N_2 PF13602.1 EGC35142.1 - 7.7e-07 30.0 0.0 7.8e-07 30.0 0.0 1.0 1 0 0 1 1 1 1 Zinc-binding dehydrogenase DUF929 PF06053.6 EGC35142.1 - 0.058 12.4 0.0 0.067 12.2 0.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF929) ADH_N PF08240.7 EGC35143.1 - 4.4e-12 45.7 0.0 6.4e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC35143.1 - 4.5e-10 39.1 0.0 9.3e-10 38.1 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGC35145.1 - 2.1e-06 28.1 0.1 2.1e-06 28.1 0.1 3.2 2 2 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC35145.1 - 3.5e-06 26.8 0.0 6e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC35145.1 - 6.3e-06 25.8 1.1 6.3e-06 25.8 0.7 2.6 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC35145.1 - 1.3e-05 25.7 0.0 4.1e-05 24.1 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC35145.1 - 0.00024 20.2 0.0 0.00024 20.2 0.0 2.5 1 1 2 3 3 3 1 Putative methyltransferase Methyltransf_25 PF13649.1 EGC35145.1 - 0.0077 16.5 0.0 0.013 15.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC35145.1 - 0.012 16.1 0.4 0.034 14.6 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGC35145.1 - 0.12 11.7 0.0 0.12 11.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase small domain Methyltransf_32 PF13679.1 EGC35145.1 - 0.26 10.9 0.1 0.26 10.9 0.1 2.4 1 1 0 2 2 2 0 Methyltransferase domain Gti1_Pac2 PF09729.4 EGC35145.1 - 0.74 9.6 16.3 2.9 7.7 5.9 2.1 2 0 0 2 2 2 0 Gti1/Pac2 family Methyltransf_9 PF08003.6 EGC35145.1 - 1.1 7.8 5.7 1.3 7.6 2.2 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1698) Dala_Dala_lig_N PF01820.16 EGC35145.1 - 5.5 7.3 8.1 19 5.5 1.8 2.4 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus DUF3464 PF11947.3 EGC35145.1 - 7.8 5.9 9.3 11 5.4 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3464) Prefoldin_2 PF01920.15 EGC35146.1 - 1.2e-20 73.1 3.5 1.4e-20 73.0 2.4 1.0 1 0 0 1 1 1 1 Prefoldin subunit DUF677 PF05055.7 EGC35146.1 - 0.0022 16.7 1.4 0.88 8.1 0.1 2.0 2 0 0 2 2 2 2 Protein of unknown function (DUF677) DASH_Dad3 PF08656.5 EGC35146.1 - 0.024 14.2 0.4 0.093 12.4 0.1 1.9 2 0 0 2 2 2 0 DASH complex subunit Dad3 Golgin_A5 PF09787.4 EGC35146.1 - 0.038 12.5 0.4 0.66 8.4 0.0 2.0 2 0 0 2 2 2 0 Golgin subfamily A member 5 Seryl_tRNA_N PF02403.17 EGC35146.1 - 0.039 13.9 1.6 0.3 11.1 0.0 2.0 2 0 0 2 2 2 0 Seryl-tRNA synthetase N-terminal domain DUF4279 PF14106.1 EGC35146.1 - 0.052 13.4 1.1 1.9 8.3 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4279) DUF2999 PF11212.3 EGC35146.1 - 0.06 13.3 0.3 2.9 7.9 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) LXG PF04740.7 EGC35146.1 - 0.1 12.3 3.1 1.8 8.2 0.1 2.0 2 0 0 2 2 2 0 LXG domain of WXG superfamily Baculo_PEP_C PF04513.7 EGC35146.1 - 0.18 11.6 2.1 1.5 8.6 0.0 2.1 2 0 0 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus Laminin_II PF06009.7 EGC35146.1 - 0.22 11.2 2.2 1.3 8.7 0.1 2.0 2 0 0 2 2 2 0 Laminin Domain II DUF3735 PF12537.3 EGC35146.1 - 0.38 10.8 2.1 3.4 7.7 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3735) IFP_35_N PF07334.8 EGC35146.1 - 0.62 10.0 5.8 0.56 10.2 1.3 2.1 2 0 0 2 2 2 0 Interferon-induced 35 kDa protein (IFP 35) N-terminus FNIP PF05725.7 EGC35147.1 - 7.4e-117 381.1 36.4 1.3e-16 60.2 0.1 9.3 7 2 2 9 9 9 9 FNIP Repeat LRR_5 PF13306.1 EGC35147.1 - 7.4e-07 28.9 1.6 0.16 11.7 0.4 3.4 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC35147.1 - 0.00047 20.0 18.3 35 4.4 0.1 9.2 5 3 6 11 11 11 4 Protein of unknown function (DUF1769) NAD_binding_8 PF13450.1 EGC35148.1 - 1.9e-17 62.9 0.0 7.7e-17 61.0 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Amino_oxidase PF01593.19 EGC35148.1 - 3.5e-11 42.8 0.0 3.2e-09 36.3 0.0 2.5 3 0 0 3 3 3 1 Flavin containing amine oxidoreductase DAO PF01266.19 EGC35148.1 - 3.7e-10 39.2 0.6 8.5e-08 31.4 0.3 2.7 2 1 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGC35148.1 - 9.2e-06 25.6 0.0 0.0023 17.8 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGC35148.1 - 1.4e-05 24.1 0.2 2.1e-05 23.5 0.2 1.2 1 0 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGC35148.1 - 9.6e-05 22.7 0.5 0.00045 20.5 0.2 2.1 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGC35148.1 - 0.00015 20.4 0.8 0.00041 18.9 0.3 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGC35148.1 - 0.00056 19.0 0.1 0.00087 18.4 0.1 1.3 1 0 0 1 1 1 1 Thi4 family NAD_binding_9 PF13454.1 EGC35148.1 - 0.016 14.9 0.3 1.7 8.4 0.1 2.4 2 0 0 2 2 2 0 FAD-NAD(P)-binding FAD_binding_3 PF01494.14 EGC35148.1 - 0.017 14.2 0.5 0.027 13.5 0.3 1.3 1 0 0 1 1 1 0 FAD binding domain Pyr_redox_3 PF13738.1 EGC35148.1 - 0.035 14.1 0.0 0.16 12.0 0.0 2.0 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC35148.1 - 0.045 12.8 0.0 0.078 12.0 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase ApbA PF02558.11 EGC35148.1 - 0.067 12.6 0.1 0.31 10.4 0.0 1.9 2 0 0 2 2 2 0 Ketopantoate reductase PanE/ApbA GIDA PF01134.17 EGC35148.1 - 0.12 11.1 0.3 0.29 9.9 0.1 1.7 2 0 0 2 2 2 0 Glucose inhibited division protein A NAD_Gly3P_dh_N PF01210.18 EGC35148.1 - 0.13 11.9 0.1 0.24 11.1 0.0 1.4 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3HCDH_N PF02737.13 EGC35148.1 - 0.15 11.7 0.2 0.27 10.8 0.1 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGC35148.1 - 0.18 11.1 1.7 0.18 11.1 0.4 1.7 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain TPK_catalytic PF04263.11 EGC35149.1 - 6.4e-23 80.6 0.0 1e-22 80.0 0.0 1.3 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, catalytic domain TPK_B1_binding PF04265.9 EGC35149.1 - 6.2e-14 51.4 0.5 1.3e-13 50.4 0.4 1.5 1 0 0 1 1 1 1 Thiamin pyrophosphokinase, vitamin B1 binding domain VSP PF03302.8 EGC35150.1 - 0.0031 16.2 0.4 0.0074 14.9 0.3 1.6 1 0 0 1 1 1 1 Giardia variant-specific surface protein ArfGap PF01412.13 EGC35151.1 - 5.3e-26 90.6 0.1 5.3e-26 90.6 0.1 4.8 3 1 0 4 4 4 1 Putative GTPase activating protein for Arf ECH_C PF13766.1 EGC35152.1 - 1.9e-43 147.3 0.3 7.8e-43 145.3 0.1 1.9 2 0 0 2 2 2 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGC35152.1 - 3.3e-24 85.3 0.1 1.3e-23 83.4 0.0 1.8 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family PAP_central PF04928.12 EGC35152.1 - 0.026 13.3 0.8 0.045 12.5 0.5 1.4 1 0 0 1 1 1 0 Poly(A) polymerase central domain FliG_N PF14842.1 EGC35152.1 - 0.084 12.9 0.3 0.24 11.5 0.1 1.8 1 1 1 2 2 2 0 FliG N-terminal domain SapB_1 PF05184.10 EGC35152.1 - 0.09 12.6 0.5 0.23 11.3 0.4 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 1 SET PF00856.23 EGC35153.1 - 8.8e-06 26.1 0.4 8.8e-06 26.1 0.2 1.8 2 1 0 2 2 2 1 SET domain Rubis-subs-bind PF09273.6 EGC35153.1 - 0.0029 17.5 0.6 0.0075 16.1 0.4 1.8 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding C-C_Bond_Lyase PF15617.1 EGC35153.1 - 0.0093 14.8 0.1 0.02 13.7 0.1 1.5 1 0 0 1 1 1 1 C-C_Bond_Lyase of the TIM-Barrel fold Kinesin PF00225.18 EGC35154.1 - 7.5e-104 347.0 3.9 7.5e-104 347.0 2.7 3.5 2 2 0 4 4 4 1 Kinesin motor domain Auxin_canalis PF05703.6 EGC35154.1 - 8.7 6.0 16.7 0.22 11.3 4.3 2.4 2 0 0 2 2 2 0 Auxin canalisation RhoGAP PF00620.22 EGC35155.1 - 1.7e-34 118.6 0.0 2.1e-34 118.3 0.0 1.1 1 0 0 1 1 1 1 RhoGAP domain NUDIX PF00293.23 EGC35156.1 - 3.9e-07 29.7 0.0 6.8e-07 28.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain DUF1980 PF09323.5 EGC35157.1 - 0.0054 16.4 8.9 0.054 13.2 1.3 2.1 1 1 1 2 2 2 2 Domain of unknown function (DUF1980) PS_Dcarbxylase PF02666.10 EGC35157.1 - 0.009 15.3 6.0 2.1 7.6 0.2 3.1 2 1 1 3 3 3 1 Phosphatidylserine decarboxylase DUF4131 PF13567.1 EGC35157.1 - 0.029 13.7 0.5 0.037 13.4 0.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Cyto_ox_2 PF02322.10 EGC35157.1 - 0.1 11.7 0.6 0.12 11.5 0.4 1.2 1 0 0 1 1 1 0 Cytochrome oxidase subunit II AA_permease_2 PF13520.1 EGC35157.1 - 0.1 11.0 2.9 0.32 9.5 2.0 1.7 1 1 0 1 1 1 0 Amino acid permease Plant_vir_prot PF01307.12 EGC35157.1 - 0.34 10.6 7.9 2.8 7.7 0.2 3.1 1 1 2 3 3 3 0 Plant viral movement protein DUF3328 PF11807.3 EGC35157.1 - 1 9.0 7.3 12 5.5 4.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF3328) DUF3753 PF12575.3 EGC35157.1 - 1.1 9.1 5.4 1.5 8.6 0.1 3.0 3 1 1 4 4 4 0 Protein of unknown function (DUF3753) OppC_N PF12911.2 EGC35157.1 - 1.6 8.1 6.3 1.7 8.1 0.1 2.6 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C DUF843 PF05814.6 EGC35157.1 - 6.8 6.5 6.7 6.8 6.5 0.0 3.0 2 1 1 3 3 3 0 Baculovirus protein of unknown function (DUF843) HSP20 PF00011.16 EGC35158.1 - 1.3e-15 57.0 0.7 3.3e-07 30.1 0.0 2.2 2 0 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.11 EGC35158.1 - 0.025 15.1 3.5 0.028 14.9 0.4 2.4 2 1 1 3 3 3 0 CS domain C2 PF00168.25 EGC35159.1 - 6e-13 48.4 0.0 9.8e-13 47.7 0.0 1.3 1 0 0 1 1 1 1 C2 domain C2 PF00168.25 EGC35160.1 - 5.3e-16 58.2 0.3 1.4e-15 56.8 0.2 1.8 1 0 0 1 1 1 1 C2 domain Membr_traf_MHD PF10540.4 EGC35160.1 - 0.00046 20.0 0.3 0.00046 20.0 0.2 4.7 5 1 0 5 5 5 1 Munc13 (mammalian uncoordinated) homology domain AMP-binding PF00501.23 EGC35161.1 - 5.1e-66 222.7 0.0 6.2e-66 222.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme BAT2_N PF07001.6 EGC35163.1 - 0.027 14.7 2.3 0.04 14.2 1.6 1.2 1 0 0 1 1 1 0 BAT2 N-terminus GLE1 PF07817.8 EGC35163.1 - 0.11 11.4 6.4 0.15 10.9 4.4 1.2 1 0 0 1 1 1 0 GLE1-like protein AAA_23 PF13476.1 EGC35163.1 - 0.75 10.0 11.6 0.92 9.8 8.0 1.1 1 0 0 1 1 1 0 AAA domain AMP-binding PF00501.23 EGC35164.1 - 5.5e-61 206.2 0.0 6.7e-61 205.9 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EGC35165.1 - 6.6e-66 222.4 0.0 8.1e-66 222.1 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme RVT_1 PF00078.22 EGC35166.1 - 1.8e-20 73.2 2.1 3.7e-20 72.2 1.4 1.5 1 0 0 1 1 1 1 Reverse transcriptase (RNA-dependent DNA polymerase) rve PF00665.21 EGC35166.1 - 2.8e-16 59.7 0.0 7.8e-16 58.2 0.0 1.8 1 0 0 1 1 1 1 Integrase core domain Chromo PF00385.19 EGC35166.1 - 1.4e-08 34.2 3.0 3.6e-08 32.9 2.1 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain RVP PF00077.15 EGC35166.1 - 0.00084 19.2 0.6 0.0037 17.1 0.4 2.1 1 0 0 1 1 1 1 Retroviral aspartyl protease Sua5_yciO_yrdC PF01300.13 EGC35166.1 - 0.06 12.5 0.1 0.52 9.5 0.0 2.4 2 0 0 2 2 2 0 Telomere recombination Asp_protease_2 PF13650.1 EGC35166.1 - 0.085 13.3 0.0 0.21 12.1 0.0 1.7 1 0 0 1 1 1 0 Aspartyl protease RVT_3 PF13456.1 EGC35166.1 - 0.11 12.2 0.0 15 5.4 0.0 2.9 2 0 0 2 2 2 0 Reverse transcriptase-like AAA_3 PF07726.6 EGC35167.1 - 6.6e-05 22.5 0.1 0.00016 21.2 0.1 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) DUF2487 PF10673.4 EGC35167.1 - 0.0057 16.4 0.5 0.071 12.9 0.7 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2487) AAA_5 PF07728.9 EGC35167.1 - 0.029 14.0 1.4 0.31 10.7 0.4 3.0 3 0 0 3 3 3 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC35167.1 - 0.3 11.2 3.7 17 5.5 0.7 3.4 2 1 1 3 3 3 0 AAA domain Asp PF00026.18 EGC35168.1 - 4.5e-18 65.5 0.2 1.6e-16 60.4 0.1 2.7 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGC35168.1 - 1.3e-10 41.0 0.0 2.6e-09 36.8 0.0 2.6 2 1 1 3 3 3 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGC35168.1 - 4.9e-09 36.3 3.3 7.7e-09 35.7 2.3 1.3 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGC35168.1 - 0.00016 22.0 0.1 0.26 11.7 0.0 3.0 3 0 0 3 3 3 2 Aspartyl protease RVP PF00077.15 EGC35168.1 - 0.011 15.6 0.0 6.2 6.8 0.0 3.0 3 0 0 3 3 3 0 Retroviral aspartyl protease Asp PF00026.18 EGC35169.1 - 5.2e-19 68.6 0.8 8.4e-19 67.9 0.5 1.3 1 1 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGC35169.1 - 2.4e-18 66.2 0.1 4.5e-18 65.3 0.0 1.5 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGC35169.1 - 4e-05 23.6 1.6 0.00014 21.8 0.4 2.0 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal gag-asp_proteas PF13975.1 EGC35169.1 - 0.00048 19.8 0.2 0.53 10.1 0.3 2.4 2 0 0 2 2 2 2 gag-polyprotein putative aspartyl protease Ibs_toxin PF13956.1 EGC35169.1 - 0.1 12.4 5.8 0.26 11.0 4.0 1.7 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Asp PF00026.18 EGC35170.1 - 5e-22 78.5 2.1 5e-22 78.5 1.5 1.7 2 0 0 2 2 2 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGC35170.1 - 1.4e-14 53.9 0.0 3.9e-14 52.4 0.0 1.7 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGC35170.1 - 1e-06 28.8 0.6 1e-06 28.8 0.4 1.8 2 0 0 2 2 2 1 Xylanase inhibitor N-terminal Asp_protease_2 PF13650.1 EGC35170.1 - 0.064 13.7 0.0 3 8.4 0.0 2.6 2 0 0 2 2 2 0 Aspartyl protease DUF45 PF01863.12 EGC35170.1 - 0.7 9.6 15.3 0.67 9.7 6.9 2.3 2 0 0 2 2 2 0 Protein of unknown function DUF45 Response_reg PF00072.19 EGC35171.1 - 2.4e-18 66.1 0.4 5.2e-18 65.0 0.0 1.8 2 0 0 2 2 2 1 Response regulator receiver domain BioY PF02632.9 EGC35172.1 - 1.7e-39 134.8 14.3 1.7e-39 134.8 9.9 1.4 1 1 0 1 1 1 1 BioY family PRE_C2HC PF07530.6 EGC35172.1 - 0.12 12.3 0.1 0.2 11.5 0.1 1.4 1 0 0 1 1 1 0 Associated with zinc fingers Sld5 PF05916.6 EGC35173.1 - 7.4e-05 23.0 1.2 7.4e-05 23.0 0.8 1.7 2 0 0 2 2 2 1 GINS complex protein Zip PF02535.17 EGC35174.1 - 1.4e-57 195.1 12.8 2.5e-56 190.9 8.9 2.0 1 1 0 1 1 1 1 ZIP Zinc transporter Ank_4 PF13637.1 EGC35175.1 - 6.7e-05 23.2 0.0 0.086 13.3 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC35175.1 - 0.00095 19.1 0.0 3.9 7.9 0.0 3.7 2 0 0 2 2 2 2 Ankyrin repeat Erf4 PF10256.4 EGC35177.1 - 0.0091 15.8 2.1 0.054 13.3 1.3 2.3 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF3154 PF11351.3 EGC35177.1 - 0.0096 15.6 0.1 0.057 13.1 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF3154) DUF829 PF05705.9 EGC35179.1 - 2.4e-33 115.8 0.2 7.6e-33 114.1 0.1 1.7 1 1 0 1 1 1 1 Eukaryotic protein of unknown function (DUF829) Peptidase_S9 PF00326.16 EGC35179.1 - 0.0048 16.1 0.2 0.017 14.3 0.1 1.8 2 0 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EGC35179.1 - 0.15 11.3 0.0 2.9 7.1 0.0 2.1 2 0 0 2 2 2 0 Dienelactone hydrolase family Pkinase PF00069.20 EGC35180.1 - 5.3e-50 169.9 0.1 5.9e-49 166.5 0.0 1.9 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35180.1 - 1.7e-18 66.6 0.0 6.7e-12 45.0 0.0 2.1 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC35180.1 - 0.00012 21.1 0.0 0.00047 19.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC35180.1 - 0.042 13.5 0.1 0.23 11.1 0.1 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC35180.1 - 0.17 10.9 0.0 0.9 8.5 0.0 1.9 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family Collagen PF01391.13 EGC35181.1 - 0.035 13.6 5.3 0.071 12.6 3.7 1.4 1 0 0 1 1 1 0 Collagen triple helix repeat (20 copies) Sec62 PF03839.11 EGC35181.1 - 0.17 11.2 0.0 0.17 11.2 0.0 2.6 3 0 0 3 3 3 0 Translocation protein Sec62 Tho2 PF11262.3 EGC35183.1 - 9.3e-68 228.4 18.3 9.3e-68 228.4 12.7 7.0 6 2 2 8 8 8 1 Transcription factor/nuclear export subunit protein 2 Thoc2 PF11732.3 EGC35183.1 - 4.1e-23 80.9 0.0 1.3e-22 79.3 0.0 2.0 1 0 0 1 1 1 1 Transcription- and export-related complex subunit Aldedh PF00171.17 EGC35184.1 - 1e-180 601.0 0.0 1.3e-180 600.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF3514 PF12027.3 EGC35185.1 - 0.14 11.4 0.6 0.48 9.6 0.4 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3514) EGF_2 PF07974.8 EGC35187.1 - 1e-05 25.5 12.3 2.9e-05 24.1 8.5 1.8 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EGC35187.1 - 0.005 16.8 2.3 0.011 15.7 1.6 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EGF PF00008.22 EGC35187.1 - 0.07 13.1 9.0 0.15 12.0 6.3 1.6 1 0 0 1 1 1 0 EGF-like domain Syndecan PF01034.15 EGC35187.1 - 0.074 12.7 0.5 0.17 11.5 0.3 1.5 1 0 0 1 1 1 0 Syndecan domain EGF_alliinase PF04863.8 EGC35187.1 - 0.11 12.4 4.0 0.27 11.2 2.8 1.7 1 0 0 1 1 1 0 Alliinase EGF-like domain PDGLE PF13190.1 EGC35187.1 - 0.17 11.5 0.0 0.36 10.5 0.0 1.5 1 0 0 1 1 1 0 PDGLE domain Syja_N PF02383.13 EGC35188.1 - 3.4e-85 285.6 0.1 3.4e-85 285.6 0.1 2.4 2 0 0 2 2 2 1 SacI homology domain RB_A PF01858.12 EGC35189.1 - 3.1e-31 108.5 2.7 3.1e-31 108.5 1.9 3.5 3 0 0 3 3 3 2 Retinoblastoma-associated protein A domain DUF3452 PF11934.3 EGC35189.1 - 8.2e-27 93.2 0.4 8.2e-27 93.2 0.3 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF3452) RB_B PF01857.15 EGC35189.1 - 2.2e-11 43.4 1.9 2.2e-11 43.4 1.3 2.8 2 0 0 2 2 2 1 Retinoblastoma-associated protein B domain Lysine_decarbox PF03641.9 EGC35190.1 - 3.8e-41 140.0 0.0 5e-41 139.6 0.0 1.2 1 0 0 1 1 1 1 Possible lysine decarboxylase Bmp PF02608.9 EGC35191.1 - 1.9e-14 53.1 2.3 3.1e-14 52.4 1.6 1.3 1 0 0 1 1 1 1 Basic membrane protein 7tm_3 PF00003.17 EGC35191.1 - 7.5e-14 51.6 23.2 1e-13 51.2 16.1 1.1 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR IncA PF04156.9 EGC35191.1 - 0.0069 15.9 4.5 0.022 14.3 3.1 1.9 1 0 0 1 1 1 1 IncA protein DUF1772 PF08592.6 EGC35191.1 - 3.6 7.3 8.2 6 6.5 1.6 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1772) FNIP PF05725.7 EGC35192.1 - 3e-77 254.3 23.6 5.5e-14 51.8 0.7 6.6 6 0 0 6 6 6 6 FNIP Repeat ADH_zinc_N PF00107.21 EGC35192.1 - 0.0058 16.1 0.0 10 5.6 0.0 3.7 1 1 3 4 4 4 2 Zinc-binding dehydrogenase Phage_min_tail PF05939.8 EGC35192.1 - 0.071 13.0 0.0 5.4 7.0 0.0 3.8 2 2 3 5 5 5 0 Phage minor tail protein Kelch_4 PF13418.1 EGC35194.1 - 1.7e-51 171.7 14.2 1.8e-08 34.0 0.0 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC35194.1 - 4.3e-45 150.9 14.5 2.3e-07 30.7 0.0 7.6 8 0 0 8 8 8 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC35194.1 - 1.1e-39 133.7 12.2 2.1e-07 30.3 0.2 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC35194.1 - 4.6e-39 131.7 6.9 1.1e-05 25.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC35194.1 - 9.4e-38 126.5 6.1 2.7e-07 30.0 0.0 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC35194.1 - 8.9e-34 114.2 20.4 1.1e-06 28.5 0.1 6.8 5 1 2 7 7 7 6 Kelch motif Aldedh PF00171.17 EGC35195.1 - 1.7e-180 600.2 0.0 2e-180 600.1 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGC35195.1 - 0.085 12.0 0.0 0.69 9.1 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) Cyclin_N PF00134.18 EGC35196.1 - 3.4e-15 55.7 3.3 4.4e-15 55.3 1.8 1.5 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC35196.1 - 4.1e-07 29.9 0.2 0.02 14.8 0.1 2.2 2 0 0 2 2 2 2 Cyclin, C-terminal domain FKBP_C PF00254.23 EGC35197.1 - 2.4e-17 62.6 0.0 2.6e-17 62.6 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Ded_cyto PF06920.8 EGC35198.1 - 7.3e-51 171.9 2.1 7.3e-51 171.9 1.5 2.0 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC35198.1 - 2.2e-41 141.5 3.6 4.6e-41 140.4 1.5 2.4 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins CDP-OH_P_transf PF01066.16 EGC35199.1 - 5.7e-14 52.2 15.7 7.6e-13 48.6 10.9 3.0 1 1 0 1 1 1 1 CDP-alcohol phosphatidyltransferase ABC_tran PF00005.22 EGC35200.1 - 3.6e-23 82.3 0.0 6e-15 55.7 0.0 2.7 2 1 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC35200.1 - 1.7e-11 43.7 1.4 0.00011 21.5 0.1 2.9 2 1 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC35200.1 - 5.2e-08 33.1 4.7 0.082 12.8 0.0 4.1 4 1 1 5 5 5 3 AAA domain AAA_15 PF13175.1 EGC35200.1 - 1.9e-06 27.2 0.1 0.26 10.2 0.0 3.4 3 0 0 3 3 3 3 AAA ATPase domain DUF258 PF03193.11 EGC35200.1 - 0.002 17.3 0.0 0.0034 16.5 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA PF00004.24 EGC35200.1 - 0.0044 17.2 0.0 0.011 15.9 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC35200.1 - 0.0068 16.4 0.0 0.019 14.9 0.0 1.7 2 0 0 2 2 2 1 AAA ATPase domain Miro PF08477.8 EGC35200.1 - 0.0082 16.6 0.0 0.13 12.8 0.0 2.7 3 0 0 3 3 3 1 Miro-like protein AAA_33 PF13671.1 EGC35200.1 - 0.01 15.7 0.0 0.023 14.5 0.0 1.6 1 0 0 1 1 1 0 AAA domain UPF0079 PF02367.12 EGC35200.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EGC35200.1 - 0.014 15.0 0.0 0.028 14.0 0.0 1.5 1 0 0 1 1 1 0 NACHT domain AAA_22 PF13401.1 EGC35200.1 - 0.017 15.2 0.0 0.037 14.1 0.0 1.7 1 0 0 1 1 1 0 AAA domain SRP54 PF00448.17 EGC35200.1 - 0.035 13.5 0.1 0.064 12.6 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_13 PF13166.1 EGC35200.1 - 0.052 12.0 0.1 1.4 7.2 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGC35200.1 - 0.079 13.2 1.6 0.12 12.6 0.6 1.7 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGC35200.1 - 0.095 11.7 0.1 0.27 10.3 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EGC35200.1 - 0.1 13.4 0.0 0.33 11.7 0.0 2.1 2 1 0 2 2 1 0 AAA domain DUF575 PF04746.7 EGC35200.1 - 0.1 12.6 0.0 0.22 11.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF575) AAA_28 PF13521.1 EGC35200.1 - 0.11 12.5 0.0 0.37 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC35200.1 - 0.11 12.0 0.0 0.22 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGC35200.1 - 0.13 11.9 0.0 0.26 10.9 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGC35200.1 - 0.22 10.3 0.8 0.32 9.8 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ACOX PF01756.14 EGC35201.1 - 7.3e-36 123.3 4.6 1e-35 122.8 0.8 2.2 2 0 0 2 2 2 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGC35201.1 - 6.6e-18 65.2 0.1 2.3e-17 63.4 0.1 2.0 2 0 0 2 2 2 1 Acyl-coenzyme A oxidase N-terminal Acyl-CoA_dh_M PF02770.14 EGC35201.1 - 9.1e-10 37.9 0.1 1.7e-09 37.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain YqzH PF14164.1 EGC35202.1 - 0.18 11.7 3.0 0.61 10.0 0.0 2.4 2 1 0 2 2 2 0 YqzH-like protein Lung_7-TM_R PF06814.8 EGC35204.1 - 0.0006 18.8 2.7 0.00066 18.7 1.9 1.0 1 0 0 1 1 1 1 Lung seven transmembrane receptor ETRAMP PF09716.5 EGC35204.1 - 0.1 12.5 0.1 7.3 6.6 0.0 2.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Lung_7-TM_R PF06814.8 EGC35205.1 - 1.2e-12 47.3 1.4 1.6e-12 47.0 1.0 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor Glyco_hydro_100 PF12899.2 EGC35205.1 - 0.1 10.9 0.0 0.12 10.7 0.0 1.1 1 0 0 1 1 1 0 Alkaline and neutral invertase Rootletin PF15035.1 EGC35206.1 - 2.5 8.0 16.6 2.7 7.9 3.3 2.5 2 0 0 2 2 2 0 Ciliary rootlet component, centrosome cohesion bZIP_1 PF00170.16 EGC35206.1 - 9.3 6.2 16.2 2 8.4 2.1 3.4 2 1 0 2 2 2 0 bZIP transcription factor Activator_LAG-3 PF11498.3 EGC35206.1 - 9.5 4.8 14.9 0.046 12.4 3.6 1.9 2 0 0 2 2 2 0 Transcriptional activator LAG-3 Pkinase PF00069.20 EGC35207.1 - 4.6e-20 71.8 0.1 6e-20 71.4 0.1 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35207.1 - 9.9e-06 24.8 0.0 1.6e-05 24.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35208.1 - 1.6e-22 79.9 6.0 6.8e-22 77.8 4.2 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35208.1 - 8.4e-08 31.6 0.7 1.7e-07 30.5 0.5 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC35208.1 - 0.0077 15.2 0.0 0.015 14.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC35208.1 - 0.018 14.1 0.0 0.033 13.2 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF456 PF04306.8 EGC35209.1 - 0.17 11.8 2.7 0.24 11.4 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF456) USP7_ICP0_bdg PF12436.3 EGC35210.1 - 0.041 13.1 0.2 0.046 12.9 0.1 1.0 1 0 0 1 1 1 0 ICP0-binding domain of Ubiquitin-specific protease 7 Potyvirid-P3 PF13608.1 EGC35210.1 - 0.13 11.3 1.5 0.14 11.2 1.0 1.0 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein Spc7 PF08317.6 EGC35211.1 - 0.003 16.2 10.6 0.0041 15.8 7.3 1.3 1 0 0 1 1 1 1 Spc7 kinetochore protein Filament PF00038.16 EGC35211.1 - 0.0046 16.4 4.3 0.026 14.0 0.2 2.1 2 0 0 2 2 2 1 Intermediate filament protein Atg14 PF10186.4 EGC35211.1 - 0.0054 15.7 5.2 0.0067 15.4 3.6 1.2 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Reo_sigmaC PF04582.7 EGC35211.1 - 0.017 14.3 0.6 0.085 12.0 0.2 1.8 1 1 1 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGC35211.1 - 0.037 13.8 8.7 0.042 13.7 0.7 2.2 2 0 0 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 WEMBL PF05701.6 EGC35211.1 - 0.064 11.7 4.9 0.11 10.9 3.4 1.3 1 1 0 1 1 1 0 Weak chloroplast movement under blue light Bacillus_HBL PF05791.6 EGC35211.1 - 0.096 12.0 9.0 0.59 9.4 1.0 2.4 1 1 0 2 2 2 0 Bacillus haemolytic enterotoxin (HBL) COG5 PF10392.4 EGC35211.1 - 0.098 12.6 5.2 0.23 11.3 0.2 2.2 1 1 1 2 2 2 0 Golgi transport complex subunit 5 DUF972 PF06156.8 EGC35211.1 - 0.11 12.8 9.3 1.7 9.0 1.0 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF972) Mnd1 PF03962.10 EGC35211.1 - 0.12 12.0 4.5 0.46 10.1 2.9 2.0 1 1 0 1 1 1 0 Mnd1 family IL15 PF02372.10 EGC35211.1 - 0.15 11.8 4.6 0.072 12.8 1.2 1.8 1 1 1 2 2 2 0 Interleukin 15 FlaC_arch PF05377.6 EGC35211.1 - 0.16 11.8 5.7 1.7 8.6 0.7 2.9 3 0 0 3 3 3 0 Flagella accessory protein C (FlaC) YlqD PF11068.3 EGC35211.1 - 0.16 11.9 5.2 0.27 11.2 0.6 2.2 1 1 1 2 2 2 0 YlqD protein DUF4164 PF13747.1 EGC35211.1 - 0.2 11.8 3.3 2.7 8.2 0.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF4164) TPR_MLP1_2 PF07926.7 EGC35211.1 - 0.22 11.2 5.5 3.3 7.4 0.9 2.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein IncA PF04156.9 EGC35211.1 - 0.26 10.8 8.7 7.9 6.0 6.1 2.5 1 1 1 2 2 2 0 IncA protein Kinetocho_Slk19 PF12709.2 EGC35211.1 - 0.36 10.9 8.6 0.13 12.3 0.9 2.9 2 1 1 3 3 3 0 Central kinetochore-associated DUF4618 PF15397.1 EGC35211.1 - 0.49 9.6 8.7 2.4 7.4 0.2 2.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4618) APG6 PF04111.7 EGC35211.1 - 0.5 9.3 8.1 0.99 8.3 5.6 1.5 1 1 0 1 1 1 0 Autophagy protein Apg6 bZIP_2 PF07716.10 EGC35211.1 - 0.54 10.1 5.5 3.2 7.6 1.3 2.9 2 0 0 2 2 2 0 Basic region leucine zipper Syntaxin-6_N PF09177.6 EGC35211.1 - 0.83 10.0 3.7 1.3 9.4 0.2 2.2 2 0 0 2 2 2 0 Syntaxin 6, N-terminal DivIC PF04977.10 EGC35211.1 - 1.2 8.6 9.5 1.7 8.1 1.2 2.7 2 1 0 2 2 2 0 Septum formation initiator Spc24 PF08286.6 EGC35211.1 - 1.3 8.7 9.3 17 5.1 4.0 2.4 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 TPD52 PF04201.10 EGC35211.1 - 1.4 8.5 7.4 1.4 8.6 0.5 2.3 2 0 0 2 2 2 0 Tumour protein D52 family Tup_N PF08581.5 EGC35211.1 - 2.5 8.3 6.3 1.3 9.2 0.5 2.7 2 1 1 3 3 3 0 Tup N-terminal RBD-FIP PF09457.5 EGC35211.1 - 3.4 7.5 7.8 2.7 7.8 1.5 3.1 3 1 0 3 3 3 0 FIP domain TBPIP PF07106.8 EGC35211.1 - 3.7 7.0 14.0 3.2 7.2 3.0 2.1 1 1 0 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) USP8_interact PF08941.5 EGC35211.1 - 4.4 6.5 5.4 1.6 8.0 0.1 2.4 2 1 1 3 3 3 0 USP8 interacting Init_tRNA_PT PF04179.7 EGC35211.1 - 4.6 6.0 8.4 1.2 7.9 1.0 2.0 1 1 0 2 2 2 0 Initiator tRNA phosphoribosyl transferase Troponin PF00992.15 EGC35211.1 - 6.5 6.8 8.6 7.6 6.6 1.8 2.2 1 1 1 2 2 2 0 Troponin DUF4200 PF13863.1 EGC35211.1 - 9.2 6.2 13.9 15 5.5 1.4 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4200) Lebercilin PF15619.1 EGC35211.1 - 9.9 5.5 10.6 2.1 7.7 0.7 2.7 2 1 0 2 2 2 0 Ciliary protein causing Leber congenital amaurosis disease Usp PF00582.21 EGC35213.1 - 0.004 17.3 0.1 0.036 14.2 0.0 2.4 2 1 0 2 2 2 1 Universal stress protein family Ribosomal_S13 PF00416.17 EGC35213.1 - 0.083 13.3 0.2 0.17 12.3 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 Peptidase_C1 PF00112.18 EGC35214.1 - 1.3e-72 244.2 2.4 1.3e-72 244.2 1.7 1.9 2 0 0 2 2 2 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC35214.1 - 4.7e-13 49.2 9.2 8.2e-13 48.4 6.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) PP-binding PF00550.20 EGC35216.1 - 0.00011 22.3 0.1 0.00012 22.2 0.1 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Dickkopf_N PF04706.7 EGC35217.1 - 0.0001 22.3 5.8 0.0001 22.3 4.0 5.9 5 1 1 6 6 6 2 Dickkopf N-terminal cysteine-rich region Macoilin PF09726.4 EGC35217.1 - 6.5 4.8 13.7 9.1 4.4 9.5 1.1 1 0 0 1 1 1 0 Transmembrane protein DUF515 PF04415.7 EGC35217.1 - 8.7 4.4 9.5 13 3.9 6.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF515) Phage_GP20 PF06810.6 EGC35218.1 - 0.0027 17.1 4.4 0.0041 16.5 3.1 1.3 1 0 0 1 1 1 1 Phage minor structural protein GP20 SecA_DEAD PF07517.9 EGC35218.1 - 0.0041 16.4 0.1 0.0045 16.3 0.0 1.1 1 0 0 1 1 1 1 SecA DEAD-like domain TTL PF03133.10 EGC35218.1 - 0.017 14.0 0.4 0.022 13.7 0.3 1.1 1 0 0 1 1 1 0 Tubulin-tyrosine ligase family CENP_C_N PF15622.1 EGC35218.1 - 0.065 12.4 4.4 0.085 12.0 3.1 1.1 1 0 0 1 1 1 0 Kinetochore assembly subunit CENP-C N-terminal DUF4163 PF13739.1 EGC35218.1 - 0.22 12.3 5.9 0.36 11.6 4.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4163) DUF633 PF04816.7 EGC35218.1 - 0.36 10.1 3.4 9.1 5.5 0.0 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF633) Pkinase PF00069.20 EGC35219.1 - 8.7e-23 80.7 1.7 2.8e-16 59.4 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35219.1 - 1.2e-21 77.0 0.0 3.3e-21 75.5 0.0 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC35219.1 - 0.1 11.6 0.3 0.22 10.5 0.2 1.5 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Beach PF02138.13 EGC35220.1 - 7.5e-110 366.6 0.1 7.5e-110 366.6 0.1 2.3 2 0 0 2 2 2 1 Beige/BEACH domain PH_BEACH PF14844.1 EGC35220.1 - 1.4e-30 105.2 2.8 1.8e-30 104.9 0.0 2.7 3 0 0 3 3 3 1 PH domain associated with Beige/BEACH Laminin_G_3 PF13385.1 EGC35220.1 - 1.7e-18 67.3 0.0 4.9e-18 65.8 0.0 1.8 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily WD40 PF00400.27 EGC35220.1 - 1.8e-16 59.2 8.6 1.5e-07 31.0 0.1 5.3 5 0 0 5 5 5 3 WD domain, G-beta repeat DUF1088 PF06469.6 EGC35220.1 - 4.5e-06 26.1 3.1 1.1e-05 24.9 2.1 1.6 1 0 0 1 1 1 1 Domain of Unknown Function (DUF1088) GRAM PF02893.15 EGC35220.1 - 0.0078 15.7 0.0 0.026 14.0 0.0 1.9 1 0 0 1 1 1 1 GRAM domain Ras PF00071.17 EGC35221.1 - 2.3e-50 170.1 0.1 4.6e-50 169.1 0.1 1.5 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35221.1 - 7.3e-18 65.1 0.1 2.9e-17 63.2 0.0 2.0 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC35221.1 - 2.9e-11 42.8 0.0 4.6e-11 42.2 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC35221.1 - 3.6e-08 33.0 0.1 7.2e-08 32.0 0.1 1.5 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC35221.1 - 0.00026 20.2 0.1 0.0004 19.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC35221.1 - 0.00046 20.1 0.5 0.0013 18.7 0.0 1.9 2 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC35221.1 - 0.0038 16.5 0.1 0.01 15.1 0.1 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGC35221.1 - 0.008 15.3 0.0 0.093 11.9 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 EGC35221.1 - 0.0094 15.2 0.0 0.039 13.2 0.0 2.0 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_22 PF13401.1 EGC35221.1 - 0.052 13.7 0.1 1 9.5 0.0 2.4 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC35221.1 - 0.11 12.4 0.0 0.19 11.6 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain PRK PF00485.13 EGC35221.1 - 0.39 10.2 3.6 8.1 5.9 0.0 2.4 2 1 0 2 2 2 0 Phosphoribulokinase / Uridine kinase family ABC2_membrane_3 PF12698.2 EGC35221.1 - 2.8 6.8 8.5 3.4 6.6 5.9 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Zip PF02535.17 EGC35222.1 - 0.6 9.0 2.8 0.69 8.8 2.0 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter ABC2_membrane_3 PF12698.2 EGC35222.1 - 4 6.3 17.4 6.5 5.6 12.1 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Syntaxin-6_N PF09177.6 EGC35222.1 - 6.2 7.2 13.6 2.5 8.5 4.2 3.0 1 1 1 2 2 2 0 Syntaxin 6, N-terminal SNF2_N PF00176.18 EGC35223.1 - 1.8e-39 135.3 0.7 1.8e-39 135.3 0.5 2.5 3 0 0 3 3 3 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC35223.1 - 6.9e-13 48.2 0.2 3.1e-12 46.1 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC35223.1 - 0.00011 21.7 0.0 0.00027 20.4 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Chordopox_A13L PF05961.6 EGC35224.1 - 0.15 11.9 0.6 0.19 11.6 0.4 1.2 1 0 0 1 1 1 0 Chordopoxvirus A13L protein PRA1 PF03208.14 EGC35224.1 - 0.92 8.8 3.4 0.99 8.7 2.4 1.1 1 0 0 1 1 1 0 PRA1 family protein ketoacyl-synt PF00109.21 EGC35225.1 - 8.9e-64 215.3 0.0 1.7e-63 214.4 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC35225.1 - 1.9e-47 162.1 0.0 3.8e-47 161.1 0.0 1.5 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC35225.1 - 8.7e-32 109.4 0.0 5e-31 107.0 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC35225.1 - 1.3e-23 83.5 0.0 2.5e-23 82.6 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC35225.1 - 6.4e-19 68.2 0.0 6.4e-19 68.2 0.0 4.1 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.1 EGC35225.1 - 5.2e-17 61.9 0.0 8.1e-17 61.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC35225.1 - 2.9e-16 59.8 0.0 5.3e-16 58.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC35225.1 - 7.8e-08 33.2 0.0 1.7e-07 32.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC35225.1 - 1.2e-07 31.4 0.1 2.8e-07 30.2 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Thiolase_N PF00108.18 EGC35225.1 - 1.5e-06 27.4 0.0 3.3e-06 26.2 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_11 PF08241.7 EGC35225.1 - 2.3e-06 27.9 0.1 1.2e-05 25.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC35225.1 - 5.7e-06 26.1 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC35225.1 - 0.0044 17.2 0.3 0.011 15.9 0.2 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_16 PF10294.4 EGC35226.1 - 8.5e-22 77.4 0.1 2.2e-21 76.0 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase Methyltransf_31 PF13847.1 EGC35226.1 - 5.1e-08 32.6 1.4 4.1e-07 29.6 0.0 2.6 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC35226.1 - 7.3e-06 26.5 0.0 2.3e-05 24.9 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC35226.1 - 0.00013 22.4 2.4 0.00059 20.2 0.0 2.9 2 1 1 3 3 3 1 Methyltransferase domain MTS PF05175.9 EGC35226.1 - 0.00055 19.3 0.0 0.00099 18.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_23 PF13489.1 EGC35226.1 - 0.0023 17.6 0.0 0.0064 16.2 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC35226.1 - 0.011 16.2 0.0 0.094 13.2 0.0 2.3 2 1 0 2 2 2 0 Methyltransferase domain PrmA PF06325.8 EGC35226.1 - 0.031 13.3 0.0 0.086 11.9 0.0 1.7 2 0 0 2 2 2 0 Ribosomal protein L11 methyltransferase (PrmA) 6PF2K PF01591.13 EGC35227.1 - 4e-79 264.7 0.0 6e-79 264.2 0.0 1.3 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGC35227.1 - 1.2e-33 116.4 0.1 3.9e-33 114.7 0.0 1.9 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGC35227.1 - 1.1e-07 31.7 0.0 2.2e-07 30.8 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC35227.1 - 0.00024 21.9 0.1 0.0041 17.9 0.0 2.6 3 0 0 3 3 3 1 AAA domain RasGEF PF00617.14 EGC35228.1 - 4.1e-11 42.9 0.3 6.9e-11 42.2 0.0 1.5 2 0 0 2 2 2 1 RasGEF domain DUF3936 PF13072.1 EGC35228.1 - 0.027 13.9 0.5 0.046 13.1 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) DUF148 PF02520.12 EGC35228.1 - 0.044 13.5 0.6 0.052 13.3 0.4 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF148 ELO PF01151.13 EGC35229.1 - 2.8e-51 174.2 23.0 5.2e-26 91.4 7.9 2.1 1 1 1 2 2 2 2 GNS1/SUR4 family Pkinase PF00069.20 EGC35230.1 - 5.8e-75 251.7 0.0 8e-75 251.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35230.1 - 2.7e-39 134.8 0.0 3.6e-39 134.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EGC35230.1 - 4.7e-19 68.5 1.4 8.3e-19 67.7 0.1 2.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC35230.1 - 1.2e-08 35.1 1.8 1.2e-06 28.7 1.3 2.6 1 1 0 1 1 1 1 Pleckstrin homology domain PH_3 PF14593.1 EGC35230.1 - 3.7e-08 33.2 2.0 4.3e-08 32.9 0.2 1.9 2 0 0 2 2 2 1 PH domain Pkinase_C PF00433.19 EGC35230.1 - 3.5e-06 27.4 0.3 6.8e-06 26.5 0.2 1.5 1 0 0 1 1 1 1 Protein kinase C terminal domain PH_8 PF15409.1 EGC35230.1 - 7.2e-06 25.9 0.9 1.9e-05 24.6 0.0 2.0 2 0 0 2 2 2 1 Pleckstrin homology domain PH_9 PF15410.1 EGC35230.1 - 0.00017 21.7 1.7 0.0014 18.7 0.1 2.7 2 1 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EGC35230.1 - 0.00054 19.9 0.0 0.0011 18.9 0.0 1.5 1 0 0 1 1 1 1 Pleckstrin homology domain Kinase-like PF14531.1 EGC35230.1 - 0.00062 18.8 0.0 0.0065 15.4 0.0 2.1 1 1 0 1 1 1 1 Kinase-like Mcp5_PH PF12814.2 EGC35230.1 - 0.03 14.2 0.2 0.056 13.3 0.1 1.4 1 0 0 1 1 1 0 Meiotic cell cortex C-terminal pleckstrin homology APH PF01636.18 EGC35230.1 - 0.037 13.7 0.0 0.72 9.5 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family PNP_UDP_1 PF01048.15 EGC35231.1 - 3.8e-30 104.6 0.0 4.5e-30 104.3 0.0 1.1 1 0 0 1 1 1 1 Phosphorylase superfamily UPF0081 PF03652.10 EGC35231.1 - 0.02 14.9 0.0 0.03 14.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0081) ABC2_membrane PF01061.19 EGC35232.1 - 1.6e-36 125.4 23.4 1.6e-36 125.4 16.2 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC35232.1 - 4.1e-26 91.9 0.0 7e-26 91.1 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC35232.1 - 1.3e-07 31.8 4.3 0.0072 16.3 0.1 3.3 3 1 0 4 4 4 2 AAA domain AAA_25 PF13481.1 EGC35232.1 - 8.4e-06 25.3 0.0 0.0013 18.1 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC35232.1 - 3.4e-05 23.0 6.1 0.011 14.8 0.1 3.1 2 1 1 3 3 3 2 AAA ATPase domain AAA_29 PF13555.1 EGC35232.1 - 7.3e-05 22.2 0.1 0.00016 21.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC35232.1 - 8e-05 21.8 0.2 0.00015 20.9 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC35232.1 - 0.00035 20.6 0.0 0.0028 17.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC35232.1 - 0.0012 19.6 0.0 0.0026 18.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC35232.1 - 0.0015 18.5 0.0 0.0024 17.8 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain SMC_N PF02463.14 EGC35232.1 - 0.0022 17.2 0.0 0.062 12.5 0.0 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_18 PF13238.1 EGC35232.1 - 0.0033 17.7 0.8 0.0085 16.3 0.0 2.0 2 0 0 2 2 2 1 AAA domain MutS_V PF00488.16 EGC35232.1 - 0.0072 15.7 0.2 0.56 9.5 0.0 2.6 3 0 0 3 3 3 1 MutS domain V AAA_30 PF13604.1 EGC35232.1 - 0.019 14.5 0.0 0.034 13.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC35232.1 - 0.02 14.5 0.9 0.03 14.0 0.1 1.7 1 1 1 2 2 2 0 Archaeal ATPase SbcCD_C PF13558.1 EGC35232.1 - 0.023 14.6 0.2 0.18 11.7 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit MMR_HSR1 PF01926.18 EGC35232.1 - 0.055 13.4 0.3 0.15 11.9 0.2 1.9 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_33 PF13671.1 EGC35232.1 - 0.064 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGC35232.1 - 0.096 12.1 0.0 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain ABC2_membrane_3 PF12698.2 EGC35232.1 - 0.097 11.6 27.8 0.051 12.6 16.6 2.2 1 1 1 2 2 2 0 ABC-2 family transporter protein NACHT PF05729.7 EGC35232.1 - 0.1 12.2 0.4 0.23 11.1 0.1 1.7 2 0 0 2 2 2 0 NACHT domain AAA_28 PF13521.1 EGC35232.1 - 0.13 12.2 0.2 0.22 11.4 0.2 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGC35232.1 - 0.3 11.3 0.0 0.3 11.3 0.0 2.5 1 1 1 2 2 2 0 AAA domain LSM14 PF12701.2 EGC35233.1 - 1.6e-30 104.7 0.0 1.6e-30 104.7 0.0 2.7 3 0 0 3 3 3 1 Scd6-like Sm domain FDF PF09532.5 EGC35233.1 - 4.5e-12 46.4 8.0 4.5e-12 46.4 5.5 3.9 3 1 1 4 4 4 1 FDF domain SM-ATX PF14438.1 EGC35233.1 - 4.1e-05 23.4 0.0 0.00013 21.8 0.0 2.0 1 0 0 1 1 1 1 Ataxin 2 SM domain DUF2215 PF10225.4 EGC35233.1 - 1.3 8.3 3.6 2.8 7.3 2.5 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) Acetyltransf_1 PF00583.19 EGC35234.1 - 6.7e-12 45.2 0.0 1.6e-11 44.0 0.0 1.7 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC35234.1 - 5.2e-09 36.1 0.0 9.5e-09 35.3 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC35234.1 - 1.2e-06 28.5 0.0 1.8e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC35234.1 - 2.8e-05 23.7 0.0 8.2e-05 22.2 0.0 1.7 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGC35234.1 - 0.0042 17.2 0.0 0.0063 16.6 0.0 1.4 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC35234.1 - 0.015 15.2 0.0 0.07 13.0 0.0 2.1 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_9 PF13527.1 EGC35234.1 - 0.029 14.2 0.0 0.11 12.2 0.0 2.1 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain TBPIP PF07106.8 EGC35235.1 - 1.4e-24 86.5 18.1 1.4e-24 86.5 12.5 1.6 2 0 0 2 2 2 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) DUF4600 PF15372.1 EGC35235.1 - 1.3e-05 25.4 10.7 1.3e-05 25.4 7.4 3.4 1 1 2 4 4 4 2 Domain of unknown function (DUF4600) Mnd1 PF03962.10 EGC35235.1 - 7.8e-05 22.4 20.3 0.00018 21.2 13.7 1.8 1 1 0 1 1 1 1 Mnd1 family DUF1664 PF07889.7 EGC35235.1 - 0.0016 18.2 4.3 0.0016 18.2 3.0 2.1 2 0 0 2 2 2 1 Protein of unknown function (DUF1664) YlqD PF11068.3 EGC35235.1 - 0.0034 17.4 17.6 0.041 13.9 7.3 2.4 1 1 1 2 2 2 2 YlqD protein Gp58 PF07902.6 EGC35235.1 - 0.0036 15.5 3.8 0.0042 15.3 2.6 1.2 1 0 0 1 1 1 1 gp58-like protein HemX PF04375.9 EGC35235.1 - 0.0084 14.7 11.0 0.014 14.0 7.6 1.3 1 0 0 1 1 1 1 HemX bZIP_2 PF07716.10 EGC35235.1 - 0.016 15.0 3.7 0.016 15.0 2.6 4.6 5 1 0 6 6 5 0 Basic region leucine zipper Herpes_BLRF2 PF05812.7 EGC35235.1 - 0.026 14.3 3.9 0.026 14.3 2.7 2.6 1 1 1 2 2 2 0 Herpesvirus BLRF2 protein ApoO PF09769.4 EGC35235.1 - 0.099 12.3 3.7 0.39 10.4 2.5 2.1 1 1 0 1 1 1 0 Apolipoprotein O DUF2935 PF11155.3 EGC35235.1 - 0.11 12.6 9.4 0.08 13.0 3.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF2935) Trehalase_Ca-bi PF07492.6 EGC35235.1 - 0.12 11.7 2.2 5.8 6.3 0.2 2.7 2 0 0 2 2 2 0 Neutral trehalase Ca2+ binding domain DUF3793 PF12672.2 EGC35235.1 - 0.13 11.7 3.8 0.18 11.3 2.1 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3793) V_ATPase_I PF01496.14 EGC35235.1 - 0.17 9.6 11.2 0.2 9.4 7.8 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DASH_Hsk3 PF08227.6 EGC35235.1 - 0.22 11.7 0.1 0.22 11.7 0.1 2.5 2 1 0 2 2 2 0 DASH complex subunit Hsk3 like YjcQ PF09639.5 EGC35235.1 - 0.35 10.9 3.1 3.2 7.9 0.0 2.5 1 1 1 2 2 2 0 YjcQ protein OmpH PF03938.9 EGC35235.1 - 0.41 10.5 22.7 0.14 12.0 13.6 1.9 1 1 0 1 1 1 0 Outer membrane protein (OmpH-like) TarH PF02203.10 EGC35235.1 - 0.71 9.6 10.2 1.2 8.9 7.1 1.3 1 0 0 1 1 1 0 Tar ligand binding domain homologue Reo_sigmaC PF04582.7 EGC35235.1 - 1.1 8.4 5.7 3.6 6.6 3.9 1.6 1 1 1 2 2 2 0 Reovirus sigma C capsid protein SOCS PF12610.3 EGC35235.1 - 1.1 9.6 5.0 1.2 9.5 2.1 2.1 2 1 0 2 2 1 0 Suppressor of cytokine signalling CorA PF01544.13 EGC35235.1 - 3.7 6.4 11.5 1.6 7.6 5.7 1.8 1 1 1 2 2 2 0 CorA-like Mg2+ transporter protein Allexi_40kDa PF05549.6 EGC35235.1 - 3.8 6.7 10.2 2.5 7.3 5.9 1.6 1 1 0 1 1 1 0 Allexivirus 40kDa protein DUF4239 PF14023.1 EGC35235.1 - 4.5 6.5 5.8 6.9 5.9 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4239) ADIP PF11559.3 EGC35235.1 - 5.9 6.7 28.6 5.8 6.8 5.2 3.8 2 1 2 4 4 4 0 Afadin- and alpha -actinin-Binding DUF2743 PF10899.3 EGC35235.1 - 6.8 6.0 10.5 1.5 8.1 5.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2743) DUF883 PF05957.8 EGC35235.1 - 7 7.1 7.9 15 6.0 2.1 2.3 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) DUF1843 PF08898.5 EGC35235.1 - 7.5 6.6 8.1 0.98 9.5 1.8 2.4 3 1 0 3 3 2 0 Domain of unknown function (DUF1843) BLOC1_2 PF10046.4 EGC35235.1 - 8.2 6.6 14.8 4 7.6 6.3 2.7 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF342 PF03961.8 EGC35235.1 - 8.8 4.6 16.1 5 5.4 9.6 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF342) OEP PF02321.13 EGC35237.1 - 0.082 12.4 4.5 0.13 11.8 2.8 1.6 1 1 0 1 1 1 0 Outer membrane efflux protein DUF2968 PF11180.3 EGC35237.1 - 0.21 10.9 6.9 0.38 10.1 4.2 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DEAD PF00270.24 EGC35239.1 - 8.3e-47 158.8 0.2 1e-44 152.0 0.0 2.9 2 1 1 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC35239.1 - 2.3e-23 81.8 0.2 6.8e-23 80.3 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC35239.1 - 0.00012 21.9 1.9 0.0034 17.2 0.0 2.6 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit SR-25 PF10500.4 EGC35239.1 - 0.013 14.9 19.3 0.021 14.2 13.4 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HAP2-GCS1 PF10699.4 EGC35240.1 - 0.0018 18.2 3.0 0.0038 17.1 0.1 2.9 3 0 0 3 3 3 1 Male gamete fusion factor SKG6 PF08693.5 EGC35240.1 - 0.19 11.0 3.6 0.65 9.3 2.5 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Toxin_5 PF05294.8 EGC35240.1 - 4.4 7.5 8.6 9.9 6.4 6.0 1.6 1 0 0 1 1 1 0 Scorpion short toxin FH2 PF02181.18 EGC35241.1 - 1e-90 304.3 5.2 1e-90 304.3 3.6 2.7 3 1 0 3 3 3 1 Formin Homology 2 Domain Drf_GBD PF06371.8 EGC35241.1 - 2.3e-35 121.6 4.7 2.3e-35 121.6 3.2 2.8 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGC35241.1 - 2.7e-34 118.3 1.5 2.7e-34 118.3 1.0 3.2 3 0 0 3 3 3 1 Diaphanous FH3 Domain Striatin PF08232.7 EGC35241.1 - 0.0032 17.7 4.9 0.0032 17.7 3.4 4.5 3 2 1 4 4 4 1 Striatin family PAH PF02671.16 EGC35241.1 - 0.029 14.0 1.3 0.27 10.9 0.0 3.2 3 0 0 3 3 3 0 Paired amphipathic helix repeat Baculo_PEP_C PF04513.7 EGC35241.1 - 0.85 9.4 26.8 0.42 10.4 0.0 5.5 4 1 2 6 6 6 0 Baculovirus polyhedron envelope protein, PEP, C terminus Kinesin-relat_1 PF12711.2 EGC35241.1 - 1.3 9.4 15.4 0.16 12.3 3.9 3.7 3 0 0 3 3 3 0 Kinesin motor DUF1664 PF07889.7 EGC35241.1 - 1.5 8.6 12.4 0.21 11.4 2.7 3.6 3 1 0 3 3 3 0 Protein of unknown function (DUF1664) DUF4140 PF13600.1 EGC35241.1 - 1.7 9.1 10.4 0.55 10.7 0.9 3.6 4 0 0 4 4 4 0 N-terminal domain of unknown function (DUF4140) FlaC_arch PF05377.6 EGC35241.1 - 7.6 6.5 17.7 12 5.8 1.5 5.3 4 1 0 4 4 4 0 Flagella accessory protein C (FlaC) HATPase_c PF02518.21 EGC35242.1 - 6.8e-52 173.8 0.2 2.5e-25 88.3 0.0 2.8 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC35242.1 - 3.6e-39 133.2 0.2 3.7e-24 84.8 0.0 3.0 2 0 0 2 2 2 2 Response regulator receiver domain HisKA PF00512.20 EGC35242.1 - 6.6e-32 109.3 4.1 6.2e-16 58.1 0.1 3.5 3 0 0 3 3 3 2 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EGC35242.1 - 1.3e-06 28.6 0.0 1.3e-06 28.6 0.0 2.4 2 0 0 2 2 2 1 PAS domain PAS_4 PF08448.5 EGC35242.1 - 0.00011 22.2 0.0 0.00023 21.1 0.0 1.6 1 0 0 1 1 1 1 PAS fold CTDII PF01556.13 EGC35243.1 - 3.2e-25 87.8 3.2 9.9e-23 79.8 0.1 3.2 3 0 0 3 3 3 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGC35243.1 - 5.6e-15 55.1 20.9 9.1e-15 54.4 14.5 1.3 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGC35243.1 - 0.0024 17.5 8.6 0.31 10.7 1.7 2.3 2 0 0 2 2 2 2 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGC35243.1 - 0.029 14.1 8.7 0.19 11.5 1.4 2.4 2 0 0 2 2 2 0 Double zinc ribbon zf-C3HC4_3 PF13920.1 EGC35243.1 - 4.7 6.9 10.6 0.11 12.2 1.0 2.2 2 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) RhoGEF PF00621.15 EGC35244.1 - 1.1e-50 172.0 0.5 2.4e-50 170.9 0.3 1.6 1 0 0 1 1 1 1 RhoGEF domain FYVE PF01363.16 EGC35244.1 - 2.1e-20 72.3 6.3 2.1e-20 72.3 4.4 2.1 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 EGC35244.1 - 7.4e-07 29.3 1.3 1.2e-06 28.6 0.0 2.1 3 0 0 3 3 3 1 PH domain FYVE_2 PF02318.11 EGC35244.1 - 4.9e-05 23.1 10.0 9.4e-05 22.3 3.3 2.6 2 0 0 2 2 2 1 FYVE-type zinc finger PEP-utilisers_N PF05524.8 EGC35244.1 - 0.11 12.2 0.0 0.22 11.3 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, N-terminal zf-MYND PF01753.13 EGC35245.1 - 2.2e-09 37.0 12.7 3.7e-09 36.3 8.8 1.4 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EGC35245.1 - 0.04 13.7 7.1 0.091 12.6 4.9 1.6 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 zf-C2HC_2 PF13913.1 EGC35245.1 - 1.4 8.6 8.6 17 5.2 0.2 3.5 3 0 0 3 3 3 0 zinc-finger of a C2HC-type ISG65-75 PF11727.3 EGC35246.1 - 0.57 9.1 10.6 0.59 9.1 7.3 1.1 1 0 0 1 1 1 0 Invariant surface glycoprotein DUF2208 PF09973.4 EGC35246.1 - 0.9 8.7 3.1 1 8.5 2.1 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) 4F5 PF04419.9 EGC35246.1 - 1.1 10.0 29.8 1.2 9.9 12.8 3.5 2 1 0 2 2 2 0 4F5 protein family Mucin PF01456.12 EGC35247.1 - 2 8.1 19.3 3.6 7.3 13.3 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Dicty_REP PF05086.7 EGC35247.1 - 2.9 5.5 9.5 4.1 5.0 6.6 1.2 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein zf-RING_2 PF13639.1 EGC35248.1 - 5.4e-09 35.7 12.6 9.4e-09 34.9 8.8 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC35248.1 - 5.5e-07 29.1 11.1 8.5e-07 28.5 7.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC35248.1 - 3.6e-06 26.5 15.8 7.3e-06 25.5 10.9 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC35248.1 - 6.5e-06 26.0 14.9 1.2e-05 25.2 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Nse PF11789.3 EGC35248.1 - 0.00012 21.5 10.3 0.00012 21.5 7.1 1.7 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-rbx1 PF12678.2 EGC35248.1 - 0.00013 22.0 12.1 0.00039 20.4 8.4 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-MIZ PF02891.15 EGC35248.1 - 0.00025 20.4 12.1 0.00025 20.4 8.4 2.1 2 0 0 2 2 2 1 MIZ/SP-RING zinc finger zf-RING_5 PF14634.1 EGC35248.1 - 0.00027 20.6 13.3 0.00065 19.3 9.2 1.7 1 1 0 1 1 1 1 zinc-RING finger domain zf-RING_6 PF14835.1 EGC35248.1 - 0.0021 17.7 5.0 0.0052 16.5 3.5 1.6 2 0 0 2 2 1 1 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC35248.1 - 0.0043 16.9 11.7 0.016 15.0 8.2 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC35248.1 - 0.0045 16.6 5.9 0.054 13.2 4.1 2.5 1 1 1 2 2 2 1 RING-type zinc-finger DUF393 PF04134.7 EGC35248.1 - 0.0065 17.5 0.0 0.0065 17.5 0.0 2.0 2 0 0 2 2 1 1 Protein of unknown function, DUF393 zf-Apc11 PF12861.2 EGC35248.1 - 0.06 13.1 3.9 0.11 12.3 2.7 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Prok-RING_4 PF14447.1 EGC35248.1 - 0.14 11.7 7.1 0.36 10.3 4.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 PBP1_TM PF14812.1 EGC35248.1 - 5.4 7.4 10.6 11 6.4 7.3 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal FNIP PF05725.7 EGC35249.1 - 1.7e-108 354.3 65.7 1.8e-16 59.8 2.2 8.7 2 2 5 10 10 10 10 FNIP Repeat EIIC-GAT PF03611.9 EGC35249.1 - 0.16 10.6 3.0 3.6 6.2 0.1 3.0 2 1 1 3 3 3 0 PTS system sugar-specific permease component DUF1769 PF08588.5 EGC35249.1 - 5.9 6.9 20.9 2.6 8.0 0.1 6.9 3 2 6 9 9 9 0 Protein of unknown function (DUF1769) OTU PF02338.14 EGC35251.1 - 1.6e-13 51.3 0.1 3.8e-13 50.0 0.1 1.6 1 0 0 1 1 1 1 OTU-like cysteine protease PAT1 PF09770.4 EGC35251.1 - 2 6.5 31.5 2.6 6.1 21.8 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGC35251.1 - 2.4 7.9 12.4 3.1 7.6 8.6 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Antimicrobial_7 PF08102.6 EGC35253.1 - 0.031 14.2 0.1 0.079 12.9 0.1 1.7 1 0 0 1 1 1 0 Scorpion antimicrobial peptide RRM_1 PF00076.17 EGC35254.1 - 4.1e-22 77.5 6.4 5.7e-14 51.5 0.4 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35254.1 - 5.2e-20 71.1 1.6 2.5e-10 40.1 0.1 3.6 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35254.1 - 1.1e-08 34.7 0.1 0.00034 20.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DNA_ligase_aden PF01653.13 EGC35255.1 - 1.4e-62 211.4 10.4 6e-56 189.6 7.2 3.2 1 1 0 1 1 1 1 NAD-dependent DNA ligase adenylation domain DNA_ligase_OB PF03120.11 EGC35255.1 - 7.6e-24 83.1 2.2 7.6e-24 83.1 1.5 2.0 2 0 0 2 2 2 1 NAD-dependent DNA ligase OB-fold domain HHH_2 PF12826.2 EGC35255.1 - 6.4e-09 35.5 0.0 1.9e-08 34.0 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif HHH_5 PF14520.1 EGC35255.1 - 0.0039 17.3 0.0 1.5 9.0 0.0 2.7 2 0 0 2 2 2 2 Helix-hairpin-helix domain DNA_ligase_ZBD PF03119.11 EGC35255.1 - 0.044 13.4 0.0 0.11 12.2 0.0 1.7 1 0 0 1 1 1 0 NAD-dependent DNA ligase C4 zinc finger domain RabGAP-TBC PF00566.13 EGC35256.1 - 1.3e-49 168.5 0.4 1.3e-49 168.5 0.2 3.8 3 2 1 4 4 4 1 Rab-GTPase-TBC domain Ank_2 PF12796.2 EGC35256.1 - 1.9e-20 72.9 3.5 4.8e-16 58.8 0.1 2.8 2 0 0 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC35256.1 - 5.7e-18 63.7 3.7 0.00018 21.1 0.2 4.7 4 0 0 4 4 4 4 Ankyrin repeat Ank_5 PF13857.1 EGC35256.1 - 5.8e-12 45.4 0.7 0.00049 20.2 0.0 4.4 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC35256.1 - 7.5e-10 39.0 0.6 2.2e-06 28.0 0.1 3.7 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC35256.1 - 2e-08 33.6 1.1 0.1 12.9 0.0 4.8 4 0 0 4 4 4 2 Ankyrin repeat Oxidored_FMN PF00724.15 EGC35256.1 - 0.042 12.8 2.8 0.08 11.9 1.9 1.4 1 0 0 1 1 1 0 NADH:flavin oxidoreductase / NADH oxidase family Peptidase_M8 PF01457.11 EGC35257.1 - 6.8e-70 235.8 2.8 9.3e-70 235.4 1.9 1.0 1 0 0 1 1 1 1 Leishmanolysin Pro_isomerase PF00160.16 EGC35258.1 - 2.4e-40 138.2 0.0 3e-40 137.9 0.0 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Meth_synt_2 PF01717.13 EGC35259.1 - 9.5e-16 57.6 0.0 4.2e-15 55.5 0.0 1.9 1 1 1 2 2 2 1 Cobalamin-independent synthase, Catalytic domain Terpene_synth_C PF03936.11 EGC35260.1 - 8.8e-05 21.8 0.0 0.00012 21.4 0.0 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain Med28 PF11594.3 EGC35260.1 - 0.031 14.5 0.5 0.058 13.6 0.3 1.4 1 0 0 1 1 1 0 Mediator complex subunit 28 Zip PF02535.17 EGC35262.1 - 2.9 6.7 5.9 11 4.8 0.0 2.3 2 1 0 2 2 2 0 ZIP Zinc transporter RNA_lig_T4_1 PF09511.5 EGC35263.1 - 3.2e-40 137.9 0.3 3.2e-40 137.9 0.2 1.9 2 0 0 2 2 2 1 RNA ligase HAD_2 PF13419.1 EGC35265.1 - 6.4e-10 39.5 0.0 0.00015 21.9 0.0 2.6 1 1 1 2 2 2 2 Haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC35265.1 - 3.7e-08 34.0 0.0 7.7e-08 33.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EGC35265.1 - 2.4e-06 27.0 0.1 5.4e-06 25.9 0.0 1.7 2 0 0 2 2 2 1 Polynucleotide kinase 3 phosphatase Hydrolase_like PF13242.1 EGC35265.1 - 2.1e-05 24.1 0.0 3.3e-05 23.5 0.0 1.4 1 0 0 1 1 1 1 HAD-hyrolase-like TM2 PF05154.11 EGC35266.1 - 4.7e-19 68.3 15.3 6.2e-19 67.9 10.6 1.1 1 0 0 1 1 1 1 TM2 domain Shisa PF13908.1 EGC35266.1 - 0.01 16.0 1.6 0.012 15.7 1.1 1.1 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator BioY PF02632.9 EGC35266.1 - 0.03 13.9 1.0 0.036 13.7 0.7 1.1 1 0 0 1 1 1 0 BioY family Snf7 PF03357.16 EGC35267.1 - 2.9e-29 101.6 26.4 3.2e-29 101.4 18.3 1.0 1 0 0 1 1 1 1 Snf7 PIG-S PF10510.4 EGC35267.1 - 0.0023 16.6 2.1 0.0028 16.4 1.4 1.2 1 0 0 1 1 1 1 Phosphatidylinositol-glycan biosynthesis class S protein Rota_NSP4 PF01452.11 EGC35267.1 - 0.39 10.0 7.8 0.68 9.2 5.4 1.4 1 1 0 1 1 1 0 Rotavirus non structural protein DUF948 PF06103.6 EGC35267.1 - 0.4 10.5 5.9 0.17 11.7 0.3 2.6 1 1 2 3 3 3 0 Bacterial protein of unknown function (DUF948) Glyco_hydro_65m PF03632.10 EGC35268.1 - 2.3e-79 266.7 0.8 3.5e-78 262.8 0.6 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 65 central catalytic domain DUF2152 PF10222.4 EGC35268.1 - 1.5e-14 53.1 0.0 1.1e-10 40.4 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized conserved protein (DUF2152) FNIP PF05725.7 EGC35269.1 - 5.8e-45 150.9 64.7 3.8e-11 42.7 2.7 9.5 9 1 0 10 10 10 8 FNIP Repeat A2L_zn_ribbon PF08792.5 EGC35272.1 - 0.091 12.2 0.6 0.091 12.2 0.4 2.1 3 0 0 3 3 3 0 A2L zinc ribbon domain Laminin_G_3 PF13385.1 EGC35272.1 - 0.093 12.9 0.1 0.12 12.6 0.1 1.2 1 0 0 1 1 1 0 Concanavalin A-like lectin/glucanases superfamily Pyr_redox PF00070.22 EGC35274.1 - 1.6e-19 70.1 0.8 1.7e-13 50.7 0.1 2.4 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC35274.1 - 1.4e-12 47.9 0.4 9.4e-05 22.3 0.0 3.7 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGC35274.1 - 9.7e-11 41.1 0.1 0.017 14.0 0.2 3.1 3 0 0 3 3 3 3 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGC35274.1 - 7.1e-09 36.0 0.1 0.00054 20.0 0.0 3.2 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC35274.1 - 3.6e-07 30.1 0.1 0.013 15.4 0.0 2.6 2 0 0 2 2 2 2 NAD(P)-binding Rossmann-like domain K_oxygenase PF13434.1 EGC35274.1 - 9e-07 28.1 0.4 0.00085 18.3 0.0 2.2 1 1 1 2 2 2 2 L-lysine 6-monooxygenase (NADPH-requiring) DUF1188 PF06690.6 EGC35274.1 - 3e-06 26.5 0.5 0.00061 19.0 0.1 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF1188) TrkA_N PF02254.13 EGC35274.1 - 1.4e-05 25.0 1.4 0.099 12.6 0.1 2.8 2 1 0 2 2 2 2 TrkA-N domain Trp_halogenase PF04820.9 EGC35274.1 - 1.5e-05 23.7 0.1 0.016 13.8 0.0 2.3 2 0 0 2 2 2 2 Tryptophan halogenase NAD_binding_7 PF13241.1 EGC35274.1 - 4.7e-05 23.5 0.6 0.078 13.2 0.0 2.6 3 0 0 3 3 2 2 Putative NAD(P)-binding NAD_binding_9 PF13454.1 EGC35274.1 - 0.00026 20.8 4.6 2.5 7.8 0.0 3.6 2 2 2 4 4 4 2 FAD-NAD(P)-binding Lycopene_cycl PF05834.7 EGC35274.1 - 0.00043 19.3 0.1 0.25 10.1 0.0 2.7 2 1 1 3 3 3 2 Lycopene cyclase protein Saccharop_dh PF03435.13 EGC35274.1 - 0.0014 17.7 0.3 0.95 8.3 0.0 2.2 2 0 0 2 2 2 2 Saccharopine dehydrogenase FAD_binding_3 PF01494.14 EGC35274.1 - 0.0017 17.4 0.0 1.2 8.0 0.0 2.3 2 0 0 2 2 2 2 FAD binding domain 3HCDH_N PF02737.13 EGC35274.1 - 0.0018 17.9 0.0 0.7 9.5 0.0 2.2 2 0 0 2 2 2 2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain HI0933_like PF03486.9 EGC35274.1 - 0.0024 16.4 0.7 0.3 9.4 0.0 2.7 3 1 0 3 3 3 1 HI0933-like protein ApbA PF02558.11 EGC35274.1 - 0.0028 17.0 0.0 1.4 8.3 0.0 2.4 2 0 0 2 2 2 2 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGC35274.1 - 0.0056 16.7 0.1 1.3 9.1 0.0 2.5 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase UDPG_MGDP_dh_N PF03721.9 EGC35274.1 - 0.013 14.9 0.2 1.3 8.3 0.0 2.3 2 0 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_Gly3P_dh_N PF01210.18 EGC35274.1 - 0.052 13.2 0.0 11 5.7 0.0 2.4 2 0 0 2 2 2 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus GPI2 PF06432.6 EGC35276.1 - 9.6e-93 310.5 16.0 1.1e-92 310.4 11.1 1.0 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase BTB_2 PF02214.17 EGC35277.1 - 5.3e-18 65.0 0.0 1.7e-17 63.4 0.0 1.9 1 0 0 1 1 1 1 BTB/POZ domain Pentapeptide PF00805.17 EGC35277.1 - 4.2e-17 60.9 17.1 5.1e-07 28.7 1.8 5.6 4 1 0 4 4 4 4 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGC35277.1 - 9.7e-16 57.3 31.5 5.7e-10 38.8 2.6 4.5 2 1 1 4 4 4 3 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EGC35277.1 - 6.9e-11 41.8 28.5 0.00032 20.5 4.1 5.9 4 1 1 5 5 5 4 Pentapeptide repeats (9 copies) CorA PF01544.13 EGC35278.1 - 1.9e-32 112.4 8.4 1.9e-32 112.4 5.8 2.2 2 1 1 3 3 3 1 CorA-like Mg2+ transporter protein PAP2 PF01569.16 EGC35279.1 - 0.017 14.8 0.0 0.035 13.7 0.0 1.6 1 0 0 1 1 1 0 PAP2 superfamily CBS PF00571.23 EGC35280.1 - 2.5e-34 116.7 5.2 2e-10 40.2 0.1 4.3 4 0 0 4 4 4 4 CBS domain SporV_AA PF12164.3 EGC35280.1 - 0.036 14.0 6.8 0.71 9.9 0.6 2.7 3 0 0 3 3 3 0 Stage V sporulation protein AA Med9 PF07544.8 EGC35281.1 - 0.00026 20.6 2.4 0.00026 20.6 1.7 3.0 2 2 0 2 2 2 1 RNA polymerase II transcription mediator complex subunit 9 Ycf1 PF05758.7 EGC35281.1 - 0.36 8.4 15.1 0.4 8.3 10.4 1.1 1 0 0 1 1 1 0 Ycf1 Zip PF02535.17 EGC35281.1 - 0.89 8.4 3.1 1.2 8.1 2.2 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter G-7-MTase PF12803.2 EGC35281.1 - 2.6 7.0 9.4 3.1 6.8 6.5 1.2 1 0 0 1 1 1 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) Astro_capsid PF03115.9 EGC35281.1 - 4.6 5.3 9.8 4.5 5.4 6.8 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor GAGA_bind PF06217.7 EGC35281.1 - 5.7 6.8 13.0 6.6 6.5 9.0 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family TRI5 PF06330.6 EGC35282.1 - 0.087 11.4 0.0 0.12 10.9 0.0 1.2 1 0 0 1 1 1 0 Trichodiene synthase (TRI5) ABC2_membrane_3 PF12698.2 EGC35283.1 - 3.8e-39 134.7 27.1 5.3e-39 134.2 18.8 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC2_membrane PF01061.19 EGC35283.1 - 2.1e-30 105.4 15.0 2.1e-30 105.4 10.4 2.5 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC35283.1 - 6.4e-25 88.0 0.0 1.3e-24 87.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_2 PF12679.2 EGC35283.1 - 3.1e-18 65.6 11.2 4e-18 65.2 7.7 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGC35283.1 - 6.6e-10 39.4 13.5 4.1e-09 36.8 0.9 3.7 2 2 1 3 3 3 1 AAA domain AAA_15 PF13175.1 EGC35283.1 - 2.4e-05 23.5 7.3 0.0046 16.0 0.1 3.0 4 0 0 4 4 4 2 AAA ATPase domain AAA_29 PF13555.1 EGC35283.1 - 0.002 17.5 0.1 0.0048 16.4 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_10 PF12846.2 EGC35283.1 - 0.0025 17.2 0.0 0.0086 15.5 0.0 1.7 2 0 0 2 2 2 1 AAA-like domain AAA_23 PF13476.1 EGC35283.1 - 0.012 16.0 0.9 0.017 15.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC35283.1 - 0.013 15.5 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGC35283.1 - 0.023 13.8 0.2 0.042 13.0 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF258 FtsK_SpoIIIE PF01580.13 EGC35283.1 - 0.045 13.2 0.1 0.077 12.4 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family SMC_N PF02463.14 EGC35283.1 - 0.045 12.9 0.2 2 7.5 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NB-ARC PF00931.17 EGC35283.1 - 0.081 11.7 0.3 0.17 10.6 0.2 1.5 1 0 0 1 1 1 0 NB-ARC domain AAA_22 PF13401.1 EGC35283.1 - 0.12 12.5 0.3 0.31 11.1 0.1 1.9 1 1 1 2 2 2 0 AAA domain AAA_18 PF13238.1 EGC35283.1 - 0.16 12.2 0.3 0.38 11.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain Abhydrolase_6 PF12697.2 EGC35284.1 - 2.9e-25 89.4 0.0 3.5e-25 89.2 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC35284.1 - 4.9e-14 52.4 0.0 8.6e-14 51.6 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC35284.1 - 3.6e-12 46.2 0.0 7e-12 45.3 0.0 1.6 1 1 0 1 1 1 1 Alpha/beta hydrolase family Hydrolase_4 PF12146.3 EGC35284.1 - 3e-10 39.8 0.0 5.5e-10 38.9 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Lipase_3 PF01764.20 EGC35284.1 - 0.00011 21.8 0.1 0.00026 20.6 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF1057 PF06342.7 EGC35284.1 - 0.00051 18.9 0.5 0.0014 17.5 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF1057) FSH1 PF03959.8 EGC35284.1 - 0.0053 16.2 0.0 1.5 8.2 0.0 2.5 2 0 0 2 2 2 1 Serine hydrolase (FSH1) POTRA_1 PF08478.5 EGC35284.1 - 0.0076 16.2 0.5 0.21 11.6 0.1 2.5 2 0 0 2 2 2 1 POTRA domain, FtsQ-type Esterase PF00756.15 EGC35284.1 - 0.016 14.6 0.1 0.04 13.3 0.1 2.0 1 1 0 1 1 1 0 Putative esterase SpoIISA_toxin PF14171.1 EGC35284.1 - 0.019 14.2 0.2 0.039 13.2 0.2 1.4 1 0 0 1 1 1 0 Toxin SpoIISA, type II toxin-antitoxin system DUF2974 PF11187.3 EGC35284.1 - 0.029 13.7 0.1 0.1 11.9 0.0 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF2974) DUF2007 PF09413.5 EGC35284.1 - 0.073 12.8 0.0 0.16 11.8 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF2007) HSF_DNA-bind PF00447.12 EGC35284.1 - 3.1 8.0 8.3 11 6.3 1.8 2.6 2 1 0 2 2 2 0 HSF-type DNA-binding WD40 PF00400.27 EGC35285.1 - 4.9e-83 270.3 46.5 1.2e-08 34.5 0.1 13.5 13 0 0 13 13 13 12 WD domain, G-beta repeat Cytochrom_D1 PF02239.11 EGC35285.1 - 2.3e-07 29.4 0.1 0.011 14.0 0.0 2.2 2 0 0 2 2 2 2 Cytochrome D1 heme domain Nup160 PF11715.3 EGC35285.1 - 5.3e-07 28.1 3.6 0.11 10.6 0.3 4.1 3 1 0 4 4 4 3 Nucleoporin Nup120/160 DUF1219 PF06755.7 EGC35286.1 - 2.7e-05 23.6 0.1 6.3e-05 22.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1219) RRM_1 PF00076.17 EGC35288.1 - 6e-17 61.0 0.0 1.3e-08 34.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35288.1 - 5.4e-15 55.1 0.1 1.6e-07 31.2 0.0 2.9 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35288.1 - 8.5e-15 54.3 0.1 8.7e-07 28.6 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) R3H PF01424.17 EGC35288.1 - 9.3e-11 41.2 0.0 1.8e-10 40.3 0.0 1.5 1 0 0 1 1 1 1 R3H domain SUZ-C PF12901.2 EGC35288.1 - 2.2e-07 30.3 0.3 2.2e-07 30.3 0.2 4.1 4 0 0 4 4 4 1 SUZ-C motif Limkain-b1 PF11608.3 EGC35288.1 - 0.00067 19.3 0.0 0.79 9.5 0.0 2.8 2 0 0 2 2 2 2 Limkain b1 Nup35_RRM_2 PF14605.1 EGC35288.1 - 0.0092 15.7 0.0 0.02 14.6 0.0 1.5 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF3535 PF12054.3 EGC35289.1 - 6.4e-89 298.5 7.3 6.4e-89 298.5 5.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF3535) SNF2_N PF00176.18 EGC35289.1 - 1.1e-71 241.0 0.0 5.8e-71 238.7 0.0 2.2 2 0 0 2 2 2 1 SNF2 family N-terminal domain HEAT PF02985.17 EGC35289.1 - 6.1e-16 57.0 0.5 0.024 14.6 0.0 8.9 8 0 0 8 8 8 3 HEAT repeat Helicase_C PF00271.26 EGC35289.1 - 3.1e-14 52.6 0.4 7.5e-13 48.1 0.0 3.3 3 0 0 3 3 3 1 Helicase conserved C-terminal domain Vac14_Fab1_bd PF12755.2 EGC35289.1 - 2.6e-08 34.1 0.2 3.9e-05 23.9 0.0 3.4 3 0 0 3 3 3 2 Vacuolar 14 Fab1-binding region HEAT_2 PF13646.1 EGC35289.1 - 5.1e-08 33.0 0.7 0.21 11.9 0.0 5.1 4 0 0 4 4 4 2 HEAT repeats HEAT_EZ PF13513.1 EGC35289.1 - 6.4e-08 32.8 1.1 0.00052 20.4 0.0 6.0 6 0 0 6 6 6 1 HEAT-like repeat Synaptobrevin PF00957.16 EGC35290.1 - 6e-26 89.8 6.7 8.8e-26 89.3 4.6 1.3 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGC35290.1 - 5.9e-18 64.1 0.1 1.1e-17 63.3 0.1 1.5 1 0 0 1 1 1 1 Regulated-SNARE-like domain Amnionless PF14828.1 EGC35290.1 - 0.067 11.6 0.3 0.09 11.2 0.2 1.2 1 0 0 1 1 1 0 Amnionless Cro PF09048.5 EGC35290.1 - 0.14 11.8 0.0 0.3 10.7 0.0 1.5 1 0 0 1 1 1 0 Cro DUF912 PF06024.7 EGC35290.1 - 0.19 11.8 1.6 0.36 10.9 1.1 1.5 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EGC35290.1 - 1.6 8.3 11.1 4.8 6.7 7.9 1.6 1 1 0 1 1 1 0 Rifin/stevor family Dimer_Tnp_hAT PF05699.9 EGC35293.1 - 3e-09 36.3 0.1 3.9e-09 36.0 0.1 1.3 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region TcdA_TcdB_pore PF12920.2 EGC35293.1 - 0.0067 14.4 0.0 0.0078 14.1 0.0 1.0 1 0 0 1 1 1 1 TcdA/TcdB pore forming domain DUF1649 PF07855.7 EGC35294.1 - 1.1e-40 139.0 2.8 1.3e-40 138.7 1.9 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) SWIRM PF04433.12 EGC35295.1 - 4.3e-19 68.4 0.2 1.4e-18 66.7 0.1 2.0 1 0 0 1 1 1 1 SWIRM domain zf-C3HC4_3 PF13920.1 EGC35297.1 - 4.1e-11 42.3 12.0 7.1e-11 41.6 8.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC35297.1 - 0.0012 18.7 12.7 0.0026 17.7 8.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC35297.1 - 0.002 17.8 14.2 0.0038 16.9 9.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain Prok-RING_4 PF14447.1 EGC35297.1 - 0.3 10.6 5.9 0.79 9.3 4.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 ComK PF06338.6 EGC35299.1 - 0.084 12.2 0.1 0.17 11.2 0.1 1.5 1 0 0 1 1 1 0 ComK protein WD40 PF00400.27 EGC35300.1 - 1.2e-57 189.8 26.1 5.2e-10 38.8 0.3 7.4 7 0 0 7 7 7 7 WD domain, G-beta repeat PRP4 PF08799.6 EGC35300.1 - 1.7e-13 49.5 4.6 4.6e-13 48.1 3.2 1.8 1 0 0 1 1 1 1 pre-mRNA processing factor 4 (PRP4) like Pan_kinase PF03309.9 EGC35300.1 - 0.029 13.8 0.1 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Type III pantothenate kinase LRR_4 PF12799.2 EGC35301.1 - 6.2e-14 51.2 83.2 0.25 11.0 2.5 15.5 7 5 8 16 16 16 13 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC35301.1 - 1.8e-10 39.7 89.0 0.19 11.8 0.3 23.1 23 4 2 25 25 25 8 Leucine Rich repeat FNIP PF05725.7 EGC35302.1 - 1.4e-65 216.9 47.6 2.3e-13 49.8 0.1 8.6 6 2 2 8 8 8 7 FNIP Repeat APG6 PF04111.7 EGC35303.1 - 2.4e-107 358.6 10.8 2.4e-107 358.6 7.5 2.2 2 0 0 2 2 2 1 Autophagy protein Apg6 AA_kinase PF00696.23 EGC35304.1 - 4e-40 137.8 0.1 4.8e-40 137.6 0.1 1.1 1 0 0 1 1 1 1 Amino acid kinase family Pkinase_Tyr PF07714.12 EGC35305.1 - 1.6e-52 178.1 1.4 3.1e-52 177.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35305.1 - 7.4e-49 166.2 0.0 7.4e-49 166.2 0.0 2.4 2 0 0 2 2 2 1 Protein kinase domain APH PF01636.18 EGC35305.1 - 0.01 15.6 0.0 0.01 15.6 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family C1_1 PF00130.17 EGC35305.1 - 0.096 12.4 17.1 0.017 14.8 9.0 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) CBM-like PF14683.1 EGC35306.1 - 0.044 13.4 1.7 0.06 12.9 1.1 1.3 1 0 0 1 1 1 0 Polysaccharide lyase family 4, domain III ABC2_membrane_3 PF12698.2 EGC35306.1 - 7.7 5.4 11.0 9.4 5.1 7.6 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein Toprim_3 PF13362.1 EGC35307.1 - 2e-06 27.9 0.0 4.6e-06 26.7 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_4 PF13662.1 EGC35307.1 - 1e-05 25.4 0.0 2.2e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Toprim domain Toprim_2 PF13155.1 EGC35307.1 - 0.0001 22.5 0.0 0.00031 21.0 0.0 1.9 1 0 0 1 1 1 1 Toprim-like KaiC PF06745.8 EGC35307.1 - 0.003 16.7 0.3 0.0056 15.8 0.2 1.3 1 0 0 1 1 1 1 KaiC Lar_restr_allev PF14354.1 EGC35307.1 - 0.041 14.1 0.1 0.14 12.4 0.0 1.9 2 0 0 2 2 2 0 Restriction alleviation protein Lar tRNA-synt_2b PF00587.20 EGC35308.1 - 8.3e-42 142.6 0.1 1.5e-41 141.8 0.1 1.4 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC35308.1 - 8.7e-22 76.8 2.0 1.7e-21 75.9 1.4 1.5 1 0 0 1 1 1 1 Anticodon binding domain TGS PF02824.16 EGC35308.1 - 3.9e-13 49.0 0.0 8.6e-13 47.9 0.0 1.6 1 0 0 1 1 1 1 TGS domain tRNA_SAD PF07973.9 EGC35308.1 - 1.9e-12 46.8 0.0 4.2e-12 45.7 0.0 1.7 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Lipase3_N PF03893.11 EGC35308.1 - 0.14 11.9 0.0 0.58 10.0 0.0 2.0 2 0 0 2 2 2 0 Lipase 3 N-terminal region DSPc PF00782.15 EGC35309.1 - 4.8e-27 94.1 2.2 8.5e-27 93.3 0.0 2.7 2 0 0 2 2 2 1 Dual specificity phosphatase, catalytic domain Gelsolin PF00626.17 EGC35309.1 - 5.5e-08 32.3 0.2 0.23 11.2 0.0 3.8 3 0 0 3 3 3 3 Gelsolin repeat SUI1 PF01253.17 EGC35310.1 - 1.8e-10 40.4 0.7 5.8e-10 38.8 0.5 1.9 1 0 0 1 1 1 1 Translation initiation factor SUI1 Mucin PF01456.12 EGC35310.1 - 7.9e-05 22.4 4.9 0.00013 21.7 3.4 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein SWIB PF02201.13 EGC35310.1 - 0.0027 17.3 0.2 0.067 12.8 0.1 2.7 2 0 0 2 2 2 1 SWIB/MDM2 domain DUF3439 PF11921.3 EGC35310.1 - 0.026 14.2 7.0 0.057 13.1 4.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) LIN37 PF15306.1 EGC35310.1 - 0.049 13.6 0.5 0.049 13.6 0.4 2.3 2 0 0 2 2 2 0 LIN37 SSP160 PF06933.6 EGC35310.1 - 3.5 5.4 11.6 4.8 5.0 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SMP PF04927.7 EGC35311.1 - 9.8e-07 28.6 2.9 1.1e-06 28.5 2.0 1.1 1 0 0 1 1 1 1 Seed maturation protein Ifi-6-16 PF06140.8 EGC35311.1 - 9.7e-06 25.2 7.3 1.1e-05 25.1 5.0 1.1 1 0 0 1 1 1 1 Interferon-induced 6-16 family nec1 PF10379.4 EGC35311.1 - 0.031 13.5 0.2 0.032 13.5 0.1 1.1 1 0 0 1 1 1 0 Virulence protein nec1 SPX PF03105.14 EGC35312.1 - 5.6e-05 23.0 23.6 7.2e-05 22.7 16.4 1.1 1 0 0 1 1 1 1 SPX domain DUF3452 PF11934.3 EGC35312.1 - 0.015 14.5 1.0 0.015 14.5 0.7 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3452) DUF3393 PF11873.3 EGC35314.1 - 0.0074 15.8 0.1 0.012 15.1 0.0 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF3393) Shisa PF13908.1 EGC35314.1 - 0.042 14.0 0.6 0.061 13.4 0.4 1.2 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator SID-1_RNA_chan PF13965.1 EGC35314.1 - 0.12 10.4 0.3 0.13 10.4 0.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 DUF3328 PF11807.3 EGC35314.1 - 0.29 10.7 1.3 0.42 10.2 0.9 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF3328) CLU PF13236.1 EGC35315.1 - 1.2e-62 211.2 0.0 3.6e-62 209.6 0.0 1.9 1 0 0 1 1 1 1 Clustered mitochondria VHP PF02209.14 EGC35315.1 - 8.7e-13 47.7 2.2 4.9e-12 45.3 1.5 2.5 1 0 0 1 1 1 1 Villin headpiece domain LRR_1 PF00560.28 EGC35315.1 - 2.5e-05 23.6 53.5 4.2 7.7 0.0 15.6 13 2 0 13 13 13 5 Leucine Rich Repeat LRR_6 PF13516.1 EGC35315.1 - 0.00023 20.9 68.9 0.58 10.3 0.1 17.4 16 3 3 19 19 19 3 Leucine Rich repeat LRR_7 PF13504.1 EGC35315.1 - 6.5 7.4 45.0 20 5.9 0.0 14.3 17 0 0 17 17 17 0 Leucine rich repeat DUF2655 PF10848.3 EGC35316.1 - 0.062 13.1 0.0 0.062 13.1 0.0 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF2655) DUF2052 PF09747.4 EGC35316.1 - 0.12 12.3 0.3 0.19 11.6 0.2 1.3 1 0 0 1 1 1 0 Coiled-coil domain containing protein (DUF2052) DUF3567 PF12091.3 EGC35316.1 - 0.12 12.3 0.5 62 3.6 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) Toxin_60 PF15607.1 EGC35317.1 - 0.0085 16.1 0.5 0.031 14.3 0.3 1.8 1 1 0 1 1 1 1 Putative toxin 60 XRN_N PF03159.13 EGC35318.1 - 3.7e-60 203.2 0.1 5.5e-60 202.6 0.1 1.3 1 1 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus BSD PF03909.12 EGC35319.1 - 7.9e-06 25.5 1.0 7.9e-06 25.5 0.7 2.9 3 0 0 3 3 3 1 BSD domain FNIP PF05725.7 EGC35320.1 - 9.1e-152 492.8 90.9 1.2e-16 60.3 1.1 10.1 1 1 10 14 14 14 14 FNIP Repeat DUF1769 PF08588.5 EGC35320.1 - 0.00069 19.5 33.0 4 7.4 0.0 11.1 5 3 9 14 14 14 4 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC35320.1 - 0.061 13.2 0.0 15 5.5 0.0 3.9 3 0 0 3 3 3 0 Phage minor tail protein CAP_N PF01213.14 EGC35322.1 - 0.047 12.9 0.7 0.071 12.3 0.5 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EGC35322.1 - 0.084 12.2 0.3 0.12 11.7 0.2 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Coiled PF05710.7 EGC35323.1 - 0.043 14.2 7.1 0.053 13.9 4.9 1.2 1 0 0 1 1 1 0 Coiled coil CAP_N PF01213.14 EGC35324.1 - 0.066 12.4 1.7 0.1 11.8 1.2 1.3 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) N terminal Mito_fiss_reg PF05308.6 EGC35324.1 - 0.077 12.3 0.4 0.098 12.0 0.3 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator Coiled PF05710.7 EGC35325.1 - 0.011 16.1 8.8 0.015 15.7 6.1 1.2 1 0 0 1 1 1 0 Coiled coil FR47 PF08445.5 EGC35327.1 - 1.7e-11 43.6 0.0 3e-11 42.9 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGC35327.1 - 3.1e-06 27.4 0.1 7.2e-06 26.2 0.1 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC35327.1 - 4.8e-06 26.5 0.0 9e-06 25.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_8 PF13523.1 EGC35327.1 - 0.00055 19.8 0.0 0.00087 19.2 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EGC35327.1 - 0.00084 18.2 1.5 0.0047 15.8 0.6 2.0 1 1 1 2 2 2 1 GNAT acetyltransferase Acetyltransf_7 PF13508.1 EGC35327.1 - 0.0017 18.4 0.0 0.0037 17.3 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Gly_acyl_tr_C PF08444.5 EGC35327.1 - 0.0042 17.0 0.0 0.012 15.6 0.0 1.7 1 0 0 1 1 1 1 Aralkyl acyl-CoA:amino acid N-acyltransferase, C-terminal region MSA-2c PF12238.3 EGC35327.1 - 0.033 13.8 0.2 0.05 13.2 0.2 1.2 1 0 0 1 1 1 0 Merozoite surface antigen 2c Acetyltransf_10 PF13673.1 EGC35327.1 - 0.059 13.5 0.0 0.16 12.0 0.0 1.7 1 1 1 2 2 2 0 Acetyltransferase (GNAT) domain DnaJ_CXXCXGXG PF00684.14 EGC35331.1 - 0.035 14.1 18.2 0.96 9.5 12.6 2.7 1 1 0 1 1 1 0 DnaJ central domain TMEM51 PF15345.1 EGC35332.1 - 0.00024 20.8 0.3 0.00031 20.5 0.2 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2370 PF10176.4 EGC35332.1 - 0.035 13.4 1.8 0.053 12.8 1.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) Tetraspannin PF00335.15 EGC35332.1 - 0.067 12.4 5.6 0.088 12.0 3.9 1.3 1 0 0 1 1 1 0 Tetraspanin family Coiled PF05710.7 EGC35333.1 - 4.2e-12 46.3 20.1 5.5e-12 45.9 13.9 1.2 1 0 0 1 1 1 1 Coiled coil DUF3304 PF11745.3 EGC35333.1 - 4.7 7.4 7.3 5.7 7.1 5.0 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF3304) Aldolase_II PF00596.16 EGC35334.1 - 5.6e-41 140.1 0.0 6.6e-41 139.9 0.0 1.0 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Pmp3 PF01679.12 EGC35336.1 - 6.6e-22 76.9 11.0 7.3e-22 76.8 7.6 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator DUF983 PF06170.7 EGC35336.1 - 0.3 11.2 3.4 0.38 10.9 2.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) DUF1056 PF06341.6 EGC35336.1 - 0.45 10.5 3.7 0.55 10.2 2.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1056) IATP PF04568.7 EGC35337.1 - 0.24 11.4 6.5 0.39 10.7 4.3 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase inhibitor, IATP ATP-synt_E PF05680.7 EGC35337.1 - 0.45 10.4 2.8 0.61 10.0 2.0 1.2 1 0 0 1 1 1 0 ATP synthase E chain ERCC4 PF02732.10 EGC35338.1 - 3.3e-30 104.7 0.3 6.9e-30 103.6 0.2 1.5 1 0 0 1 1 1 1 ERCC4 domain HHH_8 PF14716.1 EGC35338.1 - 1.6e-07 31.3 0.0 3.8e-07 30.1 0.0 1.7 2 0 0 2 2 2 1 Helix-hairpin-helix domain HHH PF00633.18 EGC35338.1 - 0.005 16.4 0.0 0.017 14.8 0.0 1.9 1 0 0 1 1 1 1 Helix-hairpin-helix motif Mucin PF01456.12 EGC35338.1 - 0.79 9.4 12.4 0.1 12.3 4.2 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein FYVE PF01363.16 EGC35339.1 - 3.3e-17 62.1 12.8 5e-17 61.5 8.3 1.7 2 0 0 2 2 2 1 FYVE zinc finger PH PF00169.24 EGC35339.1 - 9e-07 29.0 10.1 1.4e-05 25.2 3.1 3.2 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC35339.1 - 2.7e-05 24.3 6.0 0.0026 18.0 0.1 3.6 1 1 1 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EGC35339.1 - 0.00013 21.8 4.0 0.095 12.5 0.0 3.0 3 0 0 3 3 3 2 PH domain IBR PF01485.16 EGC35339.1 - 0.00052 19.8 4.3 0.0015 18.3 3.0 1.8 1 0 0 1 1 1 1 IBR domain Med11 PF10280.4 EGC35339.1 - 0.0024 17.8 1.5 0.0024 17.8 1.0 2.4 2 2 0 2 2 2 1 Mediator complex protein FYVE_2 PF02318.11 EGC35339.1 - 0.007 16.2 7.7 0.018 14.9 5.3 1.7 1 0 0 1 1 1 1 FYVE-type zinc finger PH_2 PF08458.5 EGC35339.1 - 0.015 15.2 0.0 0.04 13.8 0.0 1.7 1 0 0 1 1 1 0 Plant pleckstrin homology-like region KLRAQ PF10205.4 EGC35339.1 - 0.62 10.1 8.5 0.84 9.7 0.9 2.9 1 1 1 2 2 2 0 Predicted coiled-coil domain-containing protein Voltage_CLC PF00654.15 EGC35340.1 - 3.4e-96 322.3 18.5 3.4e-96 322.3 12.8 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGC35340.1 - 1e-15 57.1 0.5 1e-07 31.5 0.0 2.4 2 0 0 2 2 2 2 CBS domain ACR_tran PF00873.14 EGC35340.1 - 0.016 12.6 2.8 0.027 11.9 1.9 1.2 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family FNIP PF05725.7 EGC35341.1 - 4.7e-11 42.4 57.8 6.2e-05 22.8 0.3 10.2 7 3 2 9 9 9 8 FNIP Repeat adh_short PF00106.20 EGC35342.1 - 2.5e-21 76.3 0.0 3.2e-21 75.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC35342.1 - 9.3e-19 68.1 0.0 1.2e-18 67.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC35342.1 - 3.8e-08 33.2 0.0 5.1e-08 32.8 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC35342.1 - 2.3e-05 23.9 0.4 0.00011 21.7 0.2 2.2 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC35342.1 - 0.00045 20.2 0.0 0.0008 19.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGC35342.1 - 0.00067 18.8 0.1 0.00092 18.4 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) RmlD_sub_bind PF04321.12 EGC35342.1 - 0.0015 17.5 0.0 0.0023 16.8 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain 3Beta_HSD PF01073.14 EGC35342.1 - 0.0018 17.0 0.1 0.0028 16.4 0.1 1.2 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Peripla_BP_4 PF13407.1 EGC35342.1 - 0.0088 15.4 0.0 0.015 14.6 0.0 1.3 1 0 0 1 1 1 1 Periplasmic binding protein domain DUF1464 PF07318.7 EGC35342.1 - 0.014 14.2 0.1 0.02 13.6 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1464) Polysacc_synt_2 PF02719.10 EGC35342.1 - 0.017 14.0 0.0 0.027 13.3 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein TrkA_N PF02254.13 EGC35342.1 - 0.028 14.4 0.1 0.057 13.4 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain DUF3875 PF12991.2 EGC35343.1 - 0.097 12.3 0.0 0.2 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3875) Transglut_core PF01841.14 EGC35344.1 - 8.5e-14 51.7 0.0 2.5e-13 50.2 0.0 1.7 1 0 0 1 1 1 1 Transglutaminase-like superfamily adh_short PF00106.20 EGC35345.1 - 2.6e-16 59.9 0.0 3.7e-16 59.5 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC35345.1 - 2e-07 31.0 0.4 7.5e-07 29.1 0.0 1.9 1 1 2 3 3 3 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC35345.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC35345.1 - 0.034 13.2 5.7 0.083 12.0 3.9 1.6 1 1 0 1 1 1 0 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC35345.1 - 0.039 13.3 0.3 0.084 12.2 0.2 1.6 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family Ribosomal_L31e PF01198.14 EGC35345.1 - 0.076 12.6 1.1 5.8 6.6 0.1 2.7 2 0 0 2 2 2 0 Ribosomal protein L31e Apc9 PF12856.2 EGC35345.1 - 0.19 11.8 2.4 0.14 12.2 0.2 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 9 FNIP PF05725.7 EGC35348.1 - 7.2e-57 189.1 43.0 3.3e-10 39.7 2.9 9.6 5 2 3 9 9 9 9 FNIP Repeat ACP53EA PF06313.6 EGC35348.1 - 0.0039 17.0 0.0 0.013 15.3 0.0 1.8 1 0 0 1 1 1 1 Drosophila ACP53EA protein LIM PF00412.17 EGC35349.1 - 3.6e-30 103.7 27.4 1.4e-12 47.4 1.7 3.1 3 0 0 3 3 3 3 LIM domain C1_1 PF00130.17 EGC35349.1 - 0.048 13.4 28.6 0.28 10.9 2.1 5.3 3 2 2 5 5 5 0 Phorbol esters/diacylglycerol binding domain (C1 domain) DUF1383 PF07134.6 EGC35349.1 - 0.13 11.1 0.2 1.5 7.6 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1383) CDC50 PF03381.10 EGC35350.1 - 6.2e-91 304.4 0.3 1.1e-90 303.5 0.1 1.5 1 1 0 1 1 1 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UPF0233 PF06781.7 EGC35350.1 - 0.0053 16.3 0.5 2.4 7.8 0.1 2.3 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0233) DUF3185 PF11381.3 EGC35350.1 - 0.42 10.4 5.3 2 8.2 0.2 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Acyl-CoA_dh_M PF02770.14 EGC35351.1 - 4.9e-10 38.7 0.0 9.9e-10 37.7 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGC35351.1 - 1.8e-08 34.6 0.0 3.7e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ACOX PF01756.14 EGC35351.1 - 7.9e-05 22.1 0.1 0.00017 20.9 0.1 1.5 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGC35351.1 - 0.013 15.8 0.2 0.035 14.4 0.0 1.9 2 0 0 2 2 2 0 Acyl-coenzyme A oxidase N-terminal Ras PF00071.17 EGC35352.1 - 2.8e-24 85.3 0.9 3.7e-24 84.9 0.6 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35352.1 - 9.8e-09 35.7 0.0 3.8e-08 33.8 0.0 1.9 1 1 1 2 2 2 1 Miro-like protein AAA_22 PF13401.1 EGC35353.1 - 6.6e-11 42.4 0.0 1.5e-10 41.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC35353.1 - 1.1e-09 38.5 0.0 2.9e-09 37.1 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA PF00004.24 EGC35353.1 - 1.9e-08 34.5 2.6 1.1e-07 32.0 0.0 2.7 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGC35353.1 - 5.4e-05 23.0 2.7 5.4e-05 23.0 1.9 2.6 2 1 0 2 2 2 1 Archaeal ATPase IstB_IS21 PF01695.12 EGC35353.1 - 0.00021 20.7 0.1 0.037 13.4 0.1 2.5 1 1 0 1 1 1 1 IstB-like ATP binding protein DUF2075 PF09848.4 EGC35353.1 - 0.00029 19.9 0.1 0.00059 18.9 0.0 1.5 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) NACHT PF05729.7 EGC35353.1 - 0.0011 18.6 0.0 0.0025 17.4 0.0 1.6 1 0 0 1 1 1 1 NACHT domain KTI12 PF08433.5 EGC35353.1 - 0.0026 17.0 0.3 0.053 12.7 0.0 2.5 2 1 1 3 3 3 1 Chromatin associated protein KTI12 AAA_5 PF07728.9 EGC35353.1 - 0.0062 16.2 0.1 0.024 14.3 0.1 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_35 PF14516.1 EGC35353.1 - 0.0069 15.0 3.2 0.058 12.0 0.5 2.5 2 1 0 2 2 2 1 AAA-like domain AAA_18 PF13238.1 EGC35353.1 - 0.024 14.9 1.8 0.16 12.2 0.0 2.7 2 0 0 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGC35353.1 - 0.031 13.7 0.0 0.063 12.7 0.0 1.4 1 0 0 1 1 1 0 Sigma-54 interaction domain FtsK_SpoIIIE PF01580.13 EGC35353.1 - 0.12 11.8 0.0 0.19 11.1 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family RNA_helicase PF00910.17 EGC35353.1 - 0.14 12.3 2.4 0.18 11.9 0.1 2.5 2 2 0 2 2 2 0 RNA helicase AAA_17 PF13207.1 EGC35353.1 - 0.18 12.6 1.6 0.75 10.6 1.1 2.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC35353.1 - 0.24 10.9 0.0 0.4 10.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain DUF2175 PF09943.4 EGC35353.1 - 6.1 6.9 10.5 1.1 9.3 0.1 3.6 4 0 0 4 4 4 0 Uncharacterized protein conserved in archaea (DUF2175) Cytokin_check_N PF10407.4 EGC35354.1 - 0.019 14.5 0.2 0.06 12.9 0.1 1.9 1 0 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus MFS_2 PF13347.1 EGC35355.1 - 1.1e-16 60.3 19.7 2.8e-16 58.9 13.7 1.6 1 1 0 1 1 1 1 MFS/sugar transport protein MFS_1 PF07690.11 EGC35355.1 - 3.3e-16 58.9 34.4 8.3e-13 47.7 14.1 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily DP PF08781.5 EGC35356.1 - 2.6e-29 101.7 6.4 2.6e-29 101.7 4.4 4.1 4 3 0 4 4 4 1 Transcription factor DP E2F_TDP PF02319.15 EGC35356.1 - 2.9e-20 71.6 0.5 8.1e-20 70.1 0.3 1.8 1 0 0 1 1 1 1 E2F/DP family winged-helix DNA-binding domain DUF3439 PF11921.3 EGC35356.1 - 0.13 11.9 4.1 0.46 10.2 2.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ThiF PF00899.16 EGC35357.1 - 5.5e-51 171.9 0.8 5.1e-30 104.0 0.0 2.8 3 0 0 3 3 3 2 ThiF family UBACT PF02134.16 EGC35357.1 - 3.9e-33 112.8 2.5 8.8e-24 82.8 0.2 3.8 3 0 0 3 3 3 3 Repeat in ubiquitin-activating (UBA) protein UBA_e1_C PF09358.5 EGC35357.1 - 8.4e-26 90.5 0.3 3.5e-25 88.5 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBA_e1_thiolCys PF10585.4 EGC35357.1 - 1.7e-22 78.4 3.7 3.4e-18 64.7 1.6 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site Rubis-subs-bind PF09273.6 EGC35358.1 - 1.6e-05 24.8 0.6 1.6e-05 24.8 0.4 1.9 2 0 0 2 2 2 1 Rubisco LSMT substrate-binding SET PF00856.23 EGC35358.1 - 5e-05 23.6 1.1 0.00086 19.6 0.8 2.8 1 1 0 1 1 1 1 SET domain FDF PF09532.5 EGC35361.1 - 0.032 14.7 2.2 0.039 14.4 1.5 1.1 1 0 0 1 1 1 0 FDF domain RRM_1 PF00076.17 EGC35362.1 - 4.3e-18 64.7 0.0 7.3e-18 63.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35362.1 - 9.7e-13 47.8 0.0 1.7e-12 47.0 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35362.1 - 3.4e-12 46.0 0.0 4.9e-12 45.5 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) zf-CCHC PF00098.18 EGC35362.1 - 2.5e-06 27.1 4.1 7.4e-06 25.6 2.8 1.9 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGC35362.1 - 0.0064 15.9 0.3 0.012 15.1 0.2 1.3 1 0 0 1 1 1 1 Zinc knuckle Nup35_RRM_2 PF14605.1 EGC35362.1 - 0.0093 15.7 0.0 0.015 15.0 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif zf-CCHC_3 PF13917.1 EGC35362.1 - 0.036 13.8 0.3 0.036 13.8 0.2 1.9 2 0 0 2 2 2 0 Zinc knuckle MIP-T3 PF10243.4 EGC35362.1 - 1.1 7.6 50.4 1.6 7.1 34.9 1.3 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Lactamase_B PF00753.22 EGC35363.1 - 4.1e-20 72.2 0.0 5.6e-20 71.8 0.0 1.2 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC35363.1 - 0.00013 21.5 0.1 0.00016 21.2 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain RNase_P_Rpp14 PF01900.14 EGC35364.1 - 5.4e-24 84.1 0.1 7.2e-24 83.7 0.1 1.2 1 0 0 1 1 1 1 Rpp14/Pop5 family Nucleoplasmin PF03066.10 EGC35364.1 - 0.0061 16.0 0.5 0.0076 15.7 0.3 1.2 1 0 0 1 1 1 1 Nucleoplasmin S-antigen PF05756.6 EGC35364.1 - 0.016 15.2 0.6 0.026 14.5 0.4 1.3 1 0 0 1 1 1 0 S-antigen protein RNase_H2_suC PF08615.6 EGC35365.1 - 6.6e-22 77.8 0.1 6.6e-22 77.8 0.0 1.8 2 0 0 2 2 2 1 Ribonuclease H2 non-catalytic subunit (Ylr154p-like) SSP160 PF06933.6 EGC35365.1 - 9.7 4.0 14.1 12 3.7 9.8 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 TPR_19 PF14559.1 EGC35366.1 - 1.1e-18 67.2 11.5 0.0091 16.3 0.1 8.7 5 3 4 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35366.1 - 2.4e-15 55.9 14.3 0.00031 20.3 0.0 6.9 5 2 1 7 7 7 4 TPR repeat Apc3 PF12895.2 EGC35366.1 - 5.8e-14 51.9 34.5 0.0072 16.4 3.4 7.2 3 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_2 PF07719.12 EGC35366.1 - 1.1e-13 49.9 21.1 0.018 14.9 0.1 9.2 10 1 1 11 11 10 5 Tetratricopeptide repeat TPR_1 PF00515.23 EGC35366.1 - 1.2e-12 46.7 27.0 0.0033 16.9 0.1 8.9 9 0 0 9 9 9 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGC35366.1 - 6.4e-11 42.0 14.9 0.0013 18.5 0.0 7.1 5 1 1 6 6 6 4 Tetratricopeptide repeat TPR_7 PF13176.1 EGC35366.1 - 8.3e-11 40.8 3.6 2.4 8.1 0.0 7.5 8 0 0 8 8 7 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGC35366.1 - 1.9e-10 41.0 0.0 0.62 10.8 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC35366.1 - 6.3e-10 38.7 0.0 0.89 10.3 0.0 7.4 8 1 1 9 9 9 2 Tetratricopeptide repeat SRP72 PF08492.7 EGC35366.1 - 1.5e-07 31.6 1.2 1.5e-07 31.6 0.8 3.1 2 0 0 2 2 2 1 SRP72 RNA-binding domain TPR_6 PF13174.1 EGC35366.1 - 1.1e-06 28.7 10.5 7.7 7.2 0.0 8.1 9 0 0 9 9 9 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC35366.1 - 3.9e-05 23.4 3.2 1.2 9.0 0.0 5.6 6 1 1 7 7 7 1 Fis1 C-terminal tetratricopeptide repeat TPR_9 PF13371.1 EGC35366.1 - 7.9e-05 22.4 0.0 3.7 7.4 0.0 4.7 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGC35366.1 - 0.00066 18.8 2.6 0.29 10.1 0.3 3.8 3 1 0 4 4 4 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC35366.1 - 0.028 14.1 26.7 7.8 6.5 0.0 8.2 7 1 1 8 8 8 0 Tetratricopeptide repeat AMP-binding PF00501.23 EGC35369.1 - 1e-66 225.1 0.0 1.3e-66 224.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC35369.1 - 0.0015 19.4 0.0 0.0026 18.6 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Neur_chan_memb PF02932.11 EGC35370.1 - 2.5 7.9 15.3 7.8 6.3 7.9 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Orn_Arg_deC_N PF02784.11 EGC35371.1 - 8e-47 159.5 0.0 1.1e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGC35371.1 - 4.2e-12 45.8 0.0 1.7e-11 43.8 0.0 1.9 1 1 0 2 2 2 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain Ras PF00071.17 EGC35372.1 - 4.7e-33 113.8 0.1 5.9e-33 113.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35372.1 - 6.6e-17 62.1 0.2 1.4e-16 61.0 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC35372.1 - 5.8e-09 35.4 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC35372.1 - 9.5e-06 25.1 0.1 4.8e-05 22.8 0.0 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC35372.1 - 0.00095 19.1 0.1 0.0028 17.5 0.0 1.8 1 1 0 2 2 2 1 50S ribosome-binding GTPase Arch_ATPase PF01637.13 EGC35372.1 - 0.0054 16.4 3.7 0.041 13.5 0.0 2.1 2 0 0 2 2 2 1 Archaeal ATPase PRK PF00485.13 EGC35372.1 - 0.032 13.8 0.1 0.12 11.8 0.0 1.8 1 1 1 2 2 2 0 Phosphoribulokinase / Uridine kinase family DUF4206 PF13901.1 EGC35372.1 - 0.078 12.5 0.5 0.11 12.0 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4206) TRP_2 PF08344.6 EGC35372.1 - 0.088 12.7 0.2 0.39 10.6 0.1 2.1 1 1 0 1 1 1 0 Transient receptor ion channel II MobB PF03205.9 EGC35372.1 - 0.1 12.2 0.4 0.64 9.7 0.0 2.1 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B Pox_D5 PF03288.11 EGC35372.1 - 0.14 12.4 0.7 0.28 11.4 0.5 1.6 1 0 0 1 1 1 0 Poxvirus D5 protein-like AAA_24 PF13479.1 EGC35372.1 - 0.2 11.2 1.6 1.1 8.8 1.1 2.0 1 1 0 1 1 1 0 AAA domain Mmp37 PF09139.6 EGC35374.1 - 2.8e-68 230.4 19.8 8.7e-56 189.3 5.2 2.7 2 1 1 3 3 3 2 Mitochondrial matrix Mmp37 DUF3300 PF11737.3 EGC35374.1 - 0.051 12.8 8.3 1.6 7.9 0.5 3.5 3 1 1 4 4 4 0 Protein of unknown function (DUF3300) DUF668 PF05003.7 EGC35374.1 - 0.085 13.0 0.2 0.41 10.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF668) DUF4083 PF13314.1 EGC35374.1 - 6.2 6.7 7.9 1 9.2 0.5 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) Glyco_hydro_15 PF00723.16 EGC35375.1 - 2.3e-55 187.9 0.0 4.2e-52 177.1 0.0 2.1 1 1 1 2 2 2 2 Glycosyl hydrolases family 15 DUF4248 PF14053.1 EGC35375.1 - 0.093 12.3 0.1 0.21 11.2 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4248) MCM PF00493.18 EGC35376.1 - 2.7e-139 463.6 0.3 3.6e-138 459.8 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGC35376.1 - 1.5e-25 90.0 3.8 5.7e-25 88.1 2.7 2.1 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC35376.1 - 8.6e-08 31.5 1.5 3.7e-05 22.9 0.0 2.9 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC35376.1 - 7.9e-07 28.8 0.0 4e-06 26.5 0.0 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC35376.1 - 0.013 15.1 0.0 0.05 13.2 0.0 2.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGC35376.1 - 0.07 12.6 0.0 16 4.9 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA PF00004.24 EGC35376.1 - 0.071 13.3 0.0 0.24 11.6 0.0 1.9 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) DUF4634 PF15465.1 EGC35378.1 - 0.71 10.0 5.1 2.2 8.5 3.1 2.2 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) ArgJ PF01960.13 EGC35379.1 - 1.1e-153 511.2 13.6 1.2e-153 511.1 9.4 1.0 1 0 0 1 1 1 1 ArgJ family CK2S PF15011.1 EGC35380.1 - 4.8e-05 23.2 1.0 0.51 10.1 0.1 3.1 2 1 0 2 2 2 2 Casein Kinase 2 substrate RhgB_N PF09284.5 EGC35380.1 - 0.0037 16.6 0.1 0.0072 15.7 0.0 1.4 1 0 0 1 1 1 1 Rhamnogalacturonase B, N-terminal Secretin_N_2 PF07655.8 EGC35380.1 - 0.0061 16.9 24.4 0.0061 16.9 16.9 4.1 3 1 1 4 4 4 1 Secretin N-terminal domain POX PF07526.6 EGC35380.1 - 0.043 14.0 6.5 0.1 12.8 4.5 1.6 1 0 0 1 1 1 0 Associated with HOX TraH_2 PF06871.6 EGC35380.1 - 4.1 6.7 5.3 4.1 6.7 2.7 1.6 2 0 0 2 2 2 0 TraH_2 Acyltransferase PF01553.16 EGC35381.1 - 1.2e-25 89.5 0.0 1.7e-25 88.9 0.0 1.2 1 0 0 1 1 1 1 Acyltransferase EST1 PF10374.4 EGC35381.1 - 0.061 13.3 0.2 0.1 12.6 0.1 1.3 1 0 0 1 1 1 0 Telomerase activating protein Est1 CAAD PF14159.1 EGC35382.1 - 0.83 9.3 14.2 0.4 10.3 0.2 4.1 4 0 0 4 4 4 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2775 PF10950.3 EGC35382.1 - 2 8.6 8.5 0.7 10.1 2.6 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF2775) Methyltransf_16 PF10294.4 EGC35383.1 - 2.4e-21 75.9 0.0 5.6e-21 74.7 0.0 1.6 1 1 1 2 2 2 1 Putative methyltransferase MTS PF05175.9 EGC35383.1 - 0.0013 18.1 0.0 0.0021 17.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGC35383.1 - 0.0086 16.6 0.0 0.014 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain BOF PF04076.8 EGC35383.1 - 0.027 14.2 0.4 0.049 13.4 0.3 1.4 1 0 0 1 1 1 0 Bacterial OB fold (BOF) protein A_thal_3526 PF09713.5 EGC35384.1 - 5.6e-18 64.8 2.9 1.1e-17 63.8 0.5 2.3 2 0 0 2 2 2 1 Plant protein 1589 of unknown function (A_thal_3526) HCaRG PF07258.9 EGC35385.1 - 2.8e-13 49.8 3.1 5.3e-13 48.8 2.1 1.4 1 1 0 1 1 1 1 HCaRG protein Ribosomal_L37 PF08561.5 EGC35385.1 - 0.077 12.5 0.1 0.097 12.2 0.1 1.3 1 0 0 1 1 1 0 Mitochondrial ribosomal protein L37 B5 PF03484.10 EGC35385.1 - 0.099 12.4 0.9 12 5.8 0.1 2.2 2 0 0 2 2 2 0 tRNA synthetase B5 domain Pkinase_Tyr PF07714.12 EGC35386.1 - 6.4e-65 218.7 0.0 6.4e-65 218.7 0.0 2.6 3 1 0 3 3 3 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35386.1 - 2.1e-57 194.2 0.0 2.1e-57 194.2 0.0 2.8 3 1 0 3 3 3 1 Protein kinase domain LRR_8 PF13855.1 EGC35386.1 - 3e-29 100.5 58.4 1.6e-09 37.3 3.9 3.9 1 1 4 5 5 5 5 Leucine rich repeat LRR_4 PF12799.2 EGC35386.1 - 7.6e-21 73.2 25.8 1.5e-10 40.4 2.4 4.9 4 0 0 4 4 4 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC35386.1 - 6.7e-11 40.6 29.3 0.2 11.8 0.2 8.5 8 0 0 8 8 8 5 Leucine Rich Repeat LRR_7 PF13504.1 EGC35386.1 - 8.3e-09 34.2 22.4 0.35 11.2 0.2 8.3 7 0 0 7 7 7 4 Leucine rich repeat LRR_6 PF13516.1 EGC35386.1 - 0.0009 19.0 27.0 0.0051 16.7 0.2 7.3 7 0 0 7 7 7 1 Leucine Rich repeat APH PF01636.18 EGC35386.1 - 0.0027 17.4 0.1 0.0027 17.4 0.1 2.6 3 0 0 3 3 3 1 Phosphotransferase enzyme family LRR_3 PF07725.7 EGC35386.1 - 0.17 11.7 4.2 0.15 11.8 0.3 2.9 2 0 0 2 2 2 0 Leucine Rich Repeat GATA PF00320.22 EGC35387.1 - 2.5e-17 61.9 4.3 8.3e-17 60.2 3.0 2.0 1 0 0 1 1 1 1 GATA zinc finger HypA PF01155.14 EGC35387.1 - 0.08 12.6 0.2 0.17 11.5 0.1 1.5 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family DZR PF12773.2 EGC35387.1 - 5.4 6.9 9.6 0.11 12.3 1.3 2.3 2 0 0 2 2 2 0 Double zinc ribbon PhoPQ_related PF10142.4 EGC35388.1 - 1.2e-125 418.8 1.7 1.3e-125 418.6 1.2 1.0 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Abhydrolase_5 PF12695.2 EGC35388.1 - 6.8e-06 25.9 0.0 1.8e-05 24.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC35388.1 - 0.0011 18.9 0.0 0.0018 18.2 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family LMBR1 PF04791.11 EGC35389.1 - 1.3e-41 142.7 14.4 1.7e-41 142.3 10.0 1.1 1 0 0 1 1 1 1 LMBR1-like membrane protein Dus PF01207.12 EGC35390.1 - 1.8e-73 247.0 0.0 3.1e-73 246.3 0.0 1.5 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) His_biosynth PF00977.16 EGC35390.1 - 0.0016 17.7 0.0 0.0026 17.0 0.0 1.3 1 0 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EGC35390.1 - 0.059 12.4 0.0 0.089 11.8 0.0 1.2 1 0 0 1 1 1 0 Thiazole biosynthesis protein ThiG Med2 PF11214.3 EGC35390.1 - 9.3 6.3 16.2 0.059 13.4 4.8 2.1 2 1 0 2 2 2 0 Mediator complex subunit 2 Porin_3 PF01459.17 EGC35391.1 - 5.8e-05 22.5 0.2 8.1e-05 22.0 0.2 1.3 1 0 0 1 1 1 1 Eukaryotic porin DUF3722 PF12519.3 EGC35391.1 - 0.00029 20.1 0.3 0.00039 19.7 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3722) DUF4264 PF14084.1 EGC35391.1 - 0.034 13.5 1.1 0.21 10.9 0.2 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF4264) FixG_C PF11614.3 EGC35391.1 - 0.071 13.2 0.1 0.13 12.4 0.1 1.4 1 0 0 1 1 1 0 IG-like fold at C-terminal of FixG, putative oxidoreductase LRR_5 PF13306.1 EGC35392.1 - 0.16 11.6 1.9 0.38 10.4 1.3 1.7 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) Mif2_N PF15624.1 EGC35392.1 - 0.21 12.1 3.6 0.24 12.0 2.5 1.1 1 0 0 1 1 1 0 Kinetochore CENP-C fungal homologue, Mif2, N-terminal Helicase_C PF00271.26 EGC35393.1 - 1.2e-10 41.0 0.0 4e-10 39.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SUV3_C PF12513.3 EGC35393.1 - 4.1e-06 26.1 0.6 1.1e-05 24.7 0.1 2.0 2 0 0 2 2 2 1 Mitochondrial degradasome RNA helicase subunit C terminal DUF3439 PF11921.3 EGC35394.1 - 0.25 11.1 12.9 0.019 14.6 3.6 2.6 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) Pkinase_Tyr PF07714.12 EGC35395.1 - 6.7e-60 202.3 0.0 1e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35395.1 - 4.2e-53 180.1 0.2 4.2e-53 180.1 0.1 2.3 3 0 0 3 3 3 1 Protein kinase domain RGS PF00615.14 EGC35395.1 - 2.2e-16 60.0 2.1 7.7e-16 58.2 1.5 2.0 1 0 0 1 1 1 1 Regulator of G protein signaling domain Atrophin-1 PF03154.10 EGC35395.1 - 0.00042 18.6 7.6 0.00042 18.6 5.3 2.2 2 1 0 2 2 2 1 Atrophin-1 family APH PF01636.18 EGC35395.1 - 0.097 12.3 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family SprA-related PF12118.3 EGC35395.1 - 5.4 6.2 20.9 0.14 11.5 8.6 2.0 2 0 0 2 2 2 0 SprA-related family Cnd3 PF12719.2 EGC35396.1 - 1.6e-21 76.5 6.8 1.6e-21 76.5 4.7 3.4 3 1 0 3 3 3 1 Nuclear condensing complex subunits, C-term domain Dicty_CTDC PF00526.13 EGC35397.1 - 0.00031 20.4 45.0 0.011 15.5 7.3 4.7 3 2 0 3 3 3 2 Dictyostelium (slime mold) repeat Synapsin_C PF02750.9 EGC35398.1 - 0.046 12.8 0.1 0.091 11.8 0.0 1.4 1 1 0 1 1 1 0 Synapsin, ATP binding domain DUF202 PF02656.10 EGC35398.1 - 0.91 9.7 7.4 1 9.6 1.0 2.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) MARVEL PF01284.18 EGC35398.1 - 7.6 6.3 11.7 2.9 7.6 3.9 2.3 2 1 0 2 2 2 0 Membrane-associating domain Syntaxin PF00804.20 EGC35399.1 - 0.042 13.9 1.5 0.042 13.9 1.0 1.8 2 0 0 2 2 2 0 Syntaxin Nipped-B_C PF12830.2 EGC35399.1 - 0.064 12.9 1.4 0.097 12.3 1.0 1.2 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF327 PF03885.8 EGC35399.1 - 0.22 11.3 3.9 0.41 10.4 2.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF327) DUF4647 PF15504.1 EGC35399.1 - 0.22 10.3 5.7 0.29 9.9 4.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4647) DUF2796 PF10986.3 EGC35399.1 - 1.8 8.5 33.2 0.96 9.4 21.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2796) KIAA1328 PF15369.1 EGC35399.1 - 4.4 7.0 11.8 6.2 6.5 8.2 1.2 1 0 0 1 1 1 0 Uncharacterised protein KIAA1328 Neur_chan_memb PF02932.11 EGC35399.1 - 6.7 6.5 7.8 9.8 5.9 5.4 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Cellulase PF00150.13 EGC35400.1 - 2.3e-10 40.1 4.4 3.4e-10 39.6 3.0 1.1 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EGC35400.1 - 5.5e-09 35.6 0.5 8.1e-09 35.0 0.4 1.2 1 0 0 1 1 1 1 Beta-galactosidase Asp PF00026.18 EGC35401.1 - 2e-114 382.1 2.9 2.4e-114 381.8 2.0 1.0 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGC35401.1 - 4.6e-11 42.9 0.3 1.2e-10 41.5 0.2 1.8 1 1 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGC35401.1 - 3.3e-05 23.4 0.0 8.8e-05 22.1 0.0 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal Asp_protease_2 PF13650.1 EGC35401.1 - 9.3e-05 22.8 0.0 0.0018 18.7 0.0 3.0 2 1 0 2 2 2 1 Aspartyl protease Oxidored_FMN PF00724.15 EGC35402.1 - 7.6e-80 268.4 0.0 9e-80 268.2 0.0 1.0 1 0 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family Dus PF01207.12 EGC35402.1 - 0.034 12.9 0.0 0.072 11.9 0.0 1.4 1 0 0 1 1 1 0 Dihydrouridine synthase (Dus) AMP-binding PF00501.23 EGC35403.1 - 1.8e-85 286.8 0.0 2.3e-85 286.5 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC35403.1 - 2e-18 67.0 0.2 4.2e-18 66.0 0.1 1.6 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain TPR_12 PF13424.1 EGC35404.1 - 8.3e-35 118.5 12.3 4.4e-07 29.7 0.0 7.7 8 0 0 8 8 7 5 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35404.1 - 1.9e-17 62.6 23.8 1.1e-05 25.0 0.1 6.9 5 2 2 8 8 7 5 TPR repeat TPR_1 PF00515.23 EGC35404.1 - 5.7e-12 44.7 30.2 0.0033 16.9 0.2 10.2 11 1 0 11 11 10 4 Tetratricopeptide repeat 2OG-FeII_Oxy_3 PF13640.1 EGC35404.1 - 1.5e-11 44.7 0.0 3.8e-11 43.3 0.0 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily TPR_2 PF07719.12 EGC35404.1 - 3.3e-10 39.1 19.4 0.13 12.2 0.0 9.2 10 0 0 10 10 10 3 Tetratricopeptide repeat Actin PF00022.14 EGC35404.1 - 3e-09 35.8 0.0 8.4e-06 24.4 0.0 2.9 3 0 0 3 3 3 2 Actin F-box-like PF12937.2 EGC35404.1 - 1.4e-06 27.9 0.8 3.6e-06 26.5 0.6 1.8 1 0 0 1 1 1 1 F-box-like Lipase_3 PF01764.20 EGC35404.1 - 1.5e-05 24.6 0.0 5.1e-05 22.9 0.0 1.9 1 0 0 1 1 1 1 Lipase (class 3) F-box PF00646.28 EGC35404.1 - 8.6e-05 22.0 1.8 0.00035 20.1 0.2 2.6 2 0 0 2 2 2 1 F-box domain AAA_22 PF13401.1 EGC35404.1 - 0.00017 21.7 0.0 0.0009 19.3 0.0 2.3 2 0 0 2 2 1 1 AAA domain TPR_7 PF13176.1 EGC35404.1 - 0.00046 19.7 0.7 6.5 6.8 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat 2OG-FeII_Oxy_4 PF13661.1 EGC35404.1 - 0.00075 19.0 0.2 0.0022 17.5 0.1 1.8 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Apc3 PF12895.2 EGC35404.1 - 0.0019 18.3 30.1 0.12 12.5 0.3 6.7 4 2 2 6 6 6 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGC35404.1 - 0.003 17.2 31.9 2.1 8.3 0.2 9.7 10 0 0 10 10 9 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC35404.1 - 0.038 14.4 0.9 53 4.5 0.0 5.4 6 0 0 6 6 5 0 Tetratricopeptide repeat AAA_29 PF13555.1 EGC35404.1 - 0.039 13.4 0.0 0.11 12.0 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain TPR_10 PF13374.1 EGC35404.1 - 0.058 13.3 0.1 25 4.9 0.0 4.6 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC35404.1 - 0.11 13.1 0.0 55 4.6 0.0 4.3 4 1 1 5 5 4 0 Tetratricopeptide repeat MIT PF04212.13 EGC35404.1 - 0.23 11.3 12.5 6 6.8 0.2 5.2 5 0 0 5 5 5 0 MIT (microtubule interacting and transport) domain AAA_25 PF13481.1 EGC35404.1 - 0.77 9.1 0.0 1.5 8.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain FNIP PF05725.7 EGC35405.1 - 1.1e-47 159.6 60.0 3.6e-09 36.4 1.6 12.9 4 3 8 14 14 14 13 FNIP Repeat zf-B_box PF00643.19 EGC35405.1 - 9.7e-06 25.3 6.5 2.5e-05 24.0 4.5 1.7 1 0 0 1 1 1 1 B-box zinc finger DUF1484 PF07363.6 EGC35405.1 - 0.064 13.6 0.1 0.13 12.6 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1484) FNIP PF05725.7 EGC35406.1 - 7.5e-41 137.8 40.8 6.4e-14 51.6 4.6 6.5 4 2 2 6 6 6 5 FNIP Repeat DUF1769 PF08588.5 EGC35406.1 - 0.00014 21.6 3.4 0.91 9.5 0.1 4.3 3 2 3 6 6 6 2 Protein of unknown function (DUF1769) LRR_8 PF13855.1 EGC35406.1 - 0.029 14.1 11.0 0.064 13.0 1.3 3.6 3 0 0 3 3 3 0 Leucine rich repeat IGFBP PF00219.13 EGC35408.1 - 0.00053 20.4 53.9 0.0052 17.2 11.8 4.1 1 1 3 4 4 4 4 Insulin-like growth factor binding protein VWC PF00093.13 EGC35408.1 - 0.0018 18.3 60.1 0.36 10.9 5.9 4.1 4 0 0 4 4 4 4 von Willebrand factor type C domain TPR_12 PF13424.1 EGC35409.1 - 2.9e-05 23.9 0.5 0.18 11.7 0.2 3.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC35409.1 - 0.0015 18.2 1.8 0.028 14.2 0.4 3.2 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35409.1 - 0.0042 16.6 2.8 0.063 12.9 0.4 2.6 1 1 1 2 2 2 1 TPR repeat TPR_1 PF00515.23 EGC35409.1 - 0.0069 15.9 0.4 0.086 12.4 0.1 2.8 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_10 PF13374.1 EGC35409.1 - 0.097 12.6 0.0 0.96 9.4 0.0 2.6 3 0 0 3 3 3 0 Tetratricopeptide repeat PAN_4 PF14295.1 EGC35410.1 - 6.7e-12 44.9 2.2 6.7e-12 44.9 1.5 3.6 3 0 0 3 3 3 1 PAN domain hEGF PF12661.2 EGC35410.1 - 7.9e-05 22.4 17.3 0.011 15.7 0.6 4.9 3 0 0 3 3 3 2 Human growth factor-like EGF SpoVAD PF07451.6 EGC35410.1 - 0.42 9.0 2.7 0.7 8.2 1.8 1.3 1 0 0 1 1 1 0 Stage V sporulation protein AD (SpoVAD) AMP-binding PF00501.23 EGC35411.1 - 1.5e-82 277.2 0.0 2e-82 276.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC35411.1 - 7.4e-18 65.2 0.2 1.5e-17 64.3 0.1 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Cyclin PF08613.6 EGC35412.1 - 0.0084 16.5 8.7 0.0084 16.5 6.1 2.9 3 1 0 3 3 3 1 Cyclin Pex14_N PF04695.8 EGC35412.1 - 0.024 14.7 2.0 0.024 14.7 1.4 4.6 3 1 1 4 4 4 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2462 PF09495.5 EGC35413.1 - 0.52 11.0 6.4 2.4 8.9 0.8 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2462) NifU_N PF01592.11 EGC35414.1 - 2.7e-51 172.7 0.2 3.5e-51 172.4 0.1 1.1 1 0 0 1 1 1 1 NifU-like N terminal domain Peptidase_S24 PF00717.18 EGC35415.1 - 3.2e-09 36.2 0.1 1.3e-08 34.3 0.0 2.1 2 0 0 2 2 2 1 Peptidase S24-like PBP1_TM PF14812.1 EGC35415.1 - 0.0093 16.2 0.5 0.016 15.5 0.3 1.3 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal PDCD2_C PF04194.8 EGC35415.1 - 0.014 14.9 0.9 0.02 14.5 0.6 1.2 1 0 0 1 1 1 0 Programmed cell death protein 2, C-terminal putative domain Peptidase_S26 PF10502.4 EGC35415.1 - 0.017 14.6 0.0 0.053 13.0 0.0 1.8 1 1 0 1 1 1 0 Signal peptidase, peptidase S26 DUF1748 PF08520.5 EGC35416.1 - 0.00011 21.7 0.3 0.015 14.9 0.2 2.0 1 1 0 1 1 1 1 Fungal protein of unknown function (DUF1748) Tetraspannin PF00335.15 EGC35417.1 - 0.02 14.1 23.9 0.057 12.6 16.6 1.9 1 1 0 1 1 1 0 Tetraspanin family DUF4131 PF13567.1 EGC35417.1 - 2.5 7.4 6.7 4 6.8 4.6 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) PH_4 PF15404.1 EGC35417.1 - 4 6.9 11.5 5.2 6.5 7.6 1.5 1 1 0 1 1 1 0 Pleckstrin homology domain TMEM169 PF15052.1 EGC35417.1 - 4.2 7.2 12.8 0.78 9.6 0.3 2.2 1 1 1 2 2 2 0 TMEM169 protein family DUF3278 PF11683.3 EGC35417.1 - 7.5 6.5 9.7 0.85 9.6 2.0 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) Ribosomal_L34e PF01199.13 EGC35418.1 - 0.11 12.6 0.5 0.95 9.7 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L34e RNase_T PF00929.19 EGC35419.1 - 3.2e-27 95.8 0.0 3.8e-27 95.5 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Calreticulin PF00262.13 EGC35419.1 - 0.027 13.1 0.1 0.037 12.6 0.0 1.1 1 0 0 1 1 1 0 Calreticulin family GCV_H PF01597.14 EGC35420.1 - 1.1e-34 118.7 0.1 1.3e-34 118.4 0.1 1.1 1 0 0 1 1 1 1 Glycine cleavage H-protein Phage_tube PF04985.9 EGC35420.1 - 0.025 13.9 0.0 0.036 13.5 0.0 1.5 1 0 0 1 1 1 0 Phage tail tube protein FII RnfC_N PF13375.1 EGC35420.1 - 0.047 13.3 0.0 0.32 10.7 0.0 2.0 2 0 0 2 2 2 0 RnfC Barrel sandwich hybrid domain DUF3260 PF11658.3 EGC35421.1 - 0.028 12.5 0.1 0.042 12.0 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) DUF3357 PF11837.3 EGC35421.1 - 0.05 13.4 0.1 0.73 9.7 0.2 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) NnrS PF05940.7 EGC35421.1 - 0.072 11.9 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NnrS protein O-antigen_lig PF13425.1 EGC35422.1 - 0.017 15.0 3.1 0.017 15.0 2.1 2.4 3 0 0 3 3 3 0 O-antigen ligase like membrane protein DUF1673 PF07895.6 EGC35422.1 - 0.096 12.1 3.5 0.47 9.9 2.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) Claudin_2 PF13903.1 EGC35422.1 - 0.37 10.4 7.7 3.9 7.1 2.9 2.5 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Tmemb_9 PF05434.6 EGC35423.1 - 0.012 15.3 0.7 0.37 10.5 0.0 2.3 2 0 0 2 2 2 0 TMEM9 DUF202 PF02656.10 EGC35423.1 - 0.038 14.2 1.6 0.34 11.1 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF202) MARVEL PF01284.18 EGC35423.1 - 0.13 12.0 9.6 0.27 11.0 6.7 1.5 1 1 0 1 1 1 0 Membrane-associating domain Claudin_2 PF13903.1 EGC35423.1 - 3.5 7.2 12.7 0.39 10.3 0.2 2.5 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF2393 PF09624.5 EGC35423.1 - 8.1 5.9 6.9 0.72 9.3 0.6 2.2 2 1 0 2 2 2 0 Protein of unknown function (DUF2393) zf-TRAF PF02176.13 EGC35424.1 - 3e-19 69.1 29.6 1.1e-13 51.2 5.4 4.9 2 2 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC35424.1 - 5.8e-07 29.4 14.2 5.8e-07 29.4 9.8 4.1 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC35424.1 - 4e-06 26.3 10.4 4e-06 26.3 7.2 3.9 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC35424.1 - 8.6e-06 25.4 11.3 8.6e-06 25.4 7.8 3.5 4 0 0 4 4 4 1 Ring finger domain Sina PF03145.11 EGC35424.1 - 0.00084 19.0 1.3 0.00084 19.0 0.9 3.9 2 1 3 5 5 5 3 Seven in absentia protein family DIM PF08194.7 EGC35425.1 - 0.053 13.4 0.7 0.077 12.9 0.0 1.6 2 0 0 2 2 2 0 DIM protein Ibs_toxin PF13956.1 EGC35425.1 - 0.54 10.1 9.8 0.96 9.3 6.8 1.4 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Med10 PF09748.4 EGC35426.1 - 0.13 12.0 0.0 0.36 10.6 0.0 1.6 2 0 0 2 2 2 0 Transcription factor subunit Med10 of Mediator complex Yae1_N PF09811.4 EGC35426.1 - 0.43 10.1 3.2 9.1 5.9 0.2 2.3 2 0 0 2 2 2 0 Essential protein Yae1, N terminal zf-C2HC5 PF06221.8 EGC35427.1 - 3.1e-19 68.4 7.3 6.2e-19 67.5 5.1 1.5 1 0 0 1 1 1 1 Putative zinc finger motif, C2HC5-type PWI PF01480.12 EGC35427.1 - 6.6 6.9 8.2 0.39 10.8 0.2 3.2 4 0 0 4 4 4 0 PWI domain SnoaL_2 PF12680.2 EGC35428.1 - 0.00032 21.0 0.0 0.19 12.1 0.0 2.3 2 0 0 2 2 2 2 SnoaL-like domain SnoaL_3 PF13474.1 EGC35428.1 - 0.01 15.8 0.0 3.8 7.5 0.0 2.8 2 1 0 2 2 2 0 SnoaL-like domain DUF2859 PF11072.3 EGC35430.1 - 0.06 12.8 0.1 0.063 12.7 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2859) DDE_Tnp_4 PF13359.1 EGC35431.1 - 0.0004 20.0 0.0 0.0012 18.4 0.0 1.9 1 0 0 1 1 1 1 DDE superfamily endonuclease HTH_Tnp_4 PF13613.1 EGC35431.1 - 0.025 14.1 0.0 0.051 13.1 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease MIP-T3 PF10243.4 EGC35431.1 - 0.59 8.5 57.2 0.86 8.0 39.6 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 BUD22 PF09073.5 EGC35431.1 - 0.91 8.5 62.9 0.57 9.1 42.4 1.4 1 1 0 1 1 1 0 BUD22 Utp14 PF04615.8 EGC35431.1 - 5 5.1 63.3 7.4 4.6 43.9 1.1 1 0 0 1 1 1 0 Utp14 protein Acyl-CoA_dh_1 PF00441.19 EGC35432.1 - 7.8e-12 45.5 0.1 1.4e-11 44.7 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGC35432.1 - 1.3e-09 37.3 0.0 3e-09 36.2 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain ACOX PF01756.14 EGC35432.1 - 0.00015 21.1 0.0 0.00036 19.9 0.0 1.6 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_ox_N PF14749.1 EGC35432.1 - 0.003 17.8 0.1 0.0061 16.8 0.0 1.6 1 0 0 1 1 1 1 Acyl-coenzyme A oxidase N-terminal BTB PF00651.26 EGC35433.1 - 1.7e-20 73.0 0.2 1.7e-20 73.0 0.2 2.8 3 1 0 3 3 3 1 BTB/POZ domain BACK PF07707.10 EGC35433.1 - 6e-05 22.8 2.2 0.093 12.5 0.0 4.2 4 1 0 4 4 4 1 BTB And C-terminal Kelch TFIIA PF03153.8 EGC35433.1 - 0.0075 16.2 5.7 0.0075 16.2 4.0 1.7 2 0 0 2 2 2 1 Transcription factor IIA, alpha/beta subunit Menin PF05053.8 EGC35433.1 - 0.18 9.9 10.8 0.56 8.3 4.7 2.4 2 0 0 2 2 2 0 Menin DUF4639 PF15479.1 EGC35433.1 - 1.5 7.4 7.9 2 6.9 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4639) Snapin_Pallidin PF14712.1 EGC35434.1 - 2.3e-22 79.1 0.3 2.3e-22 79.1 0.2 2.1 2 0 0 2 2 2 1 Snapin/Pallidin COG5 PF10392.4 EGC35434.1 - 0.0027 17.6 6.4 0.0027 17.6 4.4 1.6 1 1 0 2 2 2 1 Golgi transport complex subunit 5 DUF3585 PF12130.3 EGC35434.1 - 0.0059 16.4 3.7 0.0059 16.4 2.6 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF3585) KxDL PF10241.4 EGC35434.1 - 0.021 14.6 2.4 3 7.7 0.0 2.3 2 0 0 2 2 2 0 Uncharacterized conserved protein TMF_DNA_bd PF12329.3 EGC35434.1 - 0.19 11.5 0.1 0.19 11.5 0.0 3.1 3 0 0 3 3 3 0 TATA element modulatory factor 1 DNA binding HTH_1 PF00126.22 EGC35434.1 - 0.34 10.6 1.9 1 9.1 0.0 2.5 2 1 1 3 3 3 0 Bacterial regulatory helix-turn-helix protein, lysR family SlyX PF04102.7 EGC35434.1 - 0.58 10.5 9.4 0.2 12.0 1.4 2.6 3 0 0 3 3 3 0 SlyX DUF1664 PF07889.7 EGC35434.1 - 0.74 9.6 5.2 4.3 7.1 0.0 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) ING PF12998.2 EGC35434.1 - 0.95 9.7 13.8 0.85 9.9 0.7 3.0 1 1 2 3 3 3 0 Inhibitor of growth proteins N-terminal histone-binding Prefoldin_2 PF01920.15 EGC35434.1 - 1.2 8.9 14.5 0.16 11.7 2.8 2.9 3 1 0 3 3 3 0 Prefoldin subunit DUF16 PF01519.11 EGC35434.1 - 2.7 8.2 14.6 1.2e+03 -0.3 10.2 2.3 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF948 PF06103.6 EGC35434.1 - 4.3 7.2 0.0 4.3 7.2 0.0 2.5 2 1 1 3 3 2 0 Bacterial protein of unknown function (DUF948) Chordopox_G3 PF06129.7 EGC35434.1 - 4.7 7.3 6.5 10 6.3 0.7 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein DUF4612 PF15389.1 EGC35434.1 - 7.3 7.2 10.2 3 8.4 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4612) DUF912 PF06024.7 EGC35434.1 - 7.5 6.6 8.4 5.4 7.1 2.2 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) WD40 PF00400.27 EGC35435.1 - 2.8e-43 144.2 15.2 2.9e-09 36.4 0.5 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat Nucleotid_trans PF03407.11 EGC35435.1 - 3.6e-32 111.8 0.3 1.5e-31 109.8 0.1 2.0 2 0 0 2 2 2 1 Nucleotide-diphospho-sugar transferase Nup160 PF11715.3 EGC35435.1 - 1.5e-05 23.3 4.8 0.33 9.0 0.0 3.9 1 1 1 3 3 3 2 Nucleoporin Nup120/160 ABC_tran PF00005.22 EGC35436.1 - 1.4e-33 116.0 0.0 2.9e-33 115.0 0.0 1.6 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGC35436.1 - 5.3e-21 75.2 10.4 7.8e-21 74.6 7.2 1.2 1 0 0 1 1 1 1 ABC transporter transmembrane region AAA_21 PF13304.1 EGC35436.1 - 3e-05 24.1 9.8 0.052 13.5 0.0 3.7 3 1 1 4 4 4 2 AAA domain SMC_N PF02463.14 EGC35436.1 - 0.00011 21.5 0.0 0.00023 20.4 0.0 1.6 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain DUF258 PF03193.11 EGC35436.1 - 0.0046 16.1 0.1 0.0089 15.2 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC35436.1 - 0.0057 16.1 0.2 0.013 15.0 0.2 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC35436.1 - 0.012 15.7 0.1 0.22 11.6 0.1 2.6 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGC35436.1 - 0.018 15.8 0.0 0.079 13.7 0.0 2.2 1 0 0 1 1 1 0 AAA domain Potyvirid-P3 PF13608.1 EGC35436.1 - 0.03 13.4 0.1 0.049 12.7 0.1 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein MCM PF00493.18 EGC35437.1 - 2.4e-129 430.8 0.1 6.3e-129 429.5 0.0 1.7 2 0 0 2 2 2 1 MCM2/3/5 family MCM_N PF14551.1 EGC35437.1 - 4.9e-19 68.9 6.4 8.5e-19 68.2 2.9 2.7 3 2 0 3 3 3 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC35437.1 - 7.7e-08 31.7 0.2 2.9e-05 23.3 0.0 2.5 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC35437.1 - 1.4e-06 28.0 0.0 1.1e-05 25.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC35437.1 - 0.0013 18.3 0.0 0.0058 16.2 0.0 2.2 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Mg_chelatase_2 PF13335.1 EGC35437.1 - 0.0051 17.1 0.1 0.026 14.9 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI EGF_2 PF07974.8 EGC35438.1 - 2.1e-05 24.5 37.9 0.056 13.6 3.2 3.6 2 1 1 3 3 3 3 EGF-like domain KaiC PF06745.8 EGC35438.1 - 0.023 13.8 0.4 0.65 9.0 0.1 2.2 1 1 0 2 2 2 0 KaiC DUF4519 PF15012.1 EGC35438.1 - 0.27 11.1 0.8 0.51 10.2 0.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) LRR_6 PF13516.1 EGC35438.1 - 0.32 11.2 2.6 7.4 6.9 0.1 3.8 2 1 1 3 3 3 0 Leucine Rich repeat Laminin_EGF PF00053.19 EGC35438.1 - 0.95 9.4 34.9 0.88 9.5 5.8 3.6 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC35439.1 - 3.5e-05 23.8 36.8 0.077 13.1 3.2 3.6 2 1 1 3 3 3 3 EGF-like domain DUF4519 PF15012.1 EGC35439.1 - 0.34 10.8 0.8 0.79 9.6 0.6 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Laminin_EGF PF00053.19 EGC35439.1 - 7.4 6.5 34.5 1.3 9.0 5.8 3.6 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) Tetraspannin PF00335.15 EGC35440.1 - 4.2e-28 98.1 12.8 5.3e-28 97.8 8.9 1.0 1 0 0 1 1 1 1 Tetraspanin family Wzy_C PF04932.10 EGC35440.1 - 0.061 13.1 0.2 0.061 13.1 0.1 2.7 3 0 0 3 3 3 0 O-Antigen ligase CcmH PF03918.9 EGC35440.1 - 0.32 9.9 3.5 0.24 10.3 0.1 2.4 1 1 2 3 3 3 0 Cytochrome C biogenesis protein G0-G1_switch_2 PF15103.1 EGC35440.1 - 0.36 11.0 2.4 8.2 6.7 0.4 2.3 2 0 0 2 2 2 0 G0/G1 switch protein 2 DUF2910 PF11139.3 EGC35440.1 - 4.8 6.2 14.2 0.19 10.8 5.2 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF2910) DUF4064 PF13273.1 EGC35440.1 - 5 7.2 21.3 2.2 8.4 8.1 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) WD40 PF00400.27 EGC35441.1 - 7.7e-17 60.4 12.7 7.1e-06 25.7 0.2 6.3 7 0 0 7 7 7 3 WD domain, G-beta repeat Sec16_C PF12931.2 EGC35441.1 - 1.8e-09 37.7 1.0 1.2e-07 31.7 0.7 2.5 1 1 0 1 1 1 1 Sec23-binding domain of Sec16 Prp18 PF02840.10 EGC35441.1 - 2.8e-05 23.9 0.2 0.00028 20.7 0.0 2.4 2 0 0 2 2 2 1 Prp18 domain Crystall_3 PF08964.5 EGC35441.1 - 0.0069 16.0 0.6 0.088 12.5 0.1 2.7 2 0 0 2 2 2 1 Beta/Gamma crystallin Translin PF01997.11 EGC35441.1 - 0.034 13.7 0.1 10 5.6 0.0 2.4 2 0 0 2 2 2 0 Translin family Uma2 PF05685.7 EGC35442.1 - 2.8e-06 26.7 0.0 3.9e-06 26.3 0.0 1.2 1 0 0 1 1 1 1 Putative restriction endonuclease TrmE_N PF10396.4 EGC35443.1 - 4.1e-37 126.6 0.0 1.3e-36 124.9 0.0 1.9 2 0 0 2 2 2 1 GTP-binding protein TrmE N-terminus MMR_HSR1 PF01926.18 EGC35443.1 - 1.8e-20 72.9 0.3 1.8e-20 72.9 0.2 2.5 2 1 0 2 2 2 1 50S ribosome-binding GTPase GTPase_Cys_C PF12631.2 EGC35443.1 - 4.9e-17 62.1 0.1 1.6e-16 60.4 0.1 2.0 1 0 0 1 1 1 1 Catalytic cysteine-containing C-terminus of GTPase, MnmE Dynamin_N PF00350.18 EGC35443.1 - 5.7e-08 32.7 2.2 2.9e-05 23.9 0.1 2.6 1 1 1 2 2 2 2 Dynamin family AAA_17 PF13207.1 EGC35443.1 - 2.9e-06 28.1 0.1 1.7e-05 25.6 0.0 2.5 2 1 0 2 2 1 1 AAA domain FeoB_N PF02421.13 EGC35443.1 - 3.7e-06 26.3 0.6 8.5e-06 25.1 0.4 1.7 1 1 0 1 1 1 1 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGC35443.1 - 4.8e-05 22.8 1.5 0.0024 17.3 0.7 2.3 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGC35443.1 - 0.00012 22.5 0.0 0.00031 21.2 0.0 1.8 1 0 0 1 1 1 1 Miro-like protein AAA_18 PF13238.1 EGC35443.1 - 0.0024 18.1 0.6 0.0024 18.1 0.4 2.8 3 1 0 3 3 2 1 AAA domain DUF258 PF03193.11 EGC35443.1 - 0.0051 16.0 1.2 0.056 12.6 0.0 2.6 3 0 0 3 3 3 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC35443.1 - 0.012 15.7 0.5 0.19 11.8 0.1 3.0 1 1 1 2 2 2 0 AAA domain AAA_28 PF13521.1 EGC35443.1 - 0.013 15.5 0.0 0.026 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC35443.1 - 0.041 13.8 0.1 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain MobB PF03205.9 EGC35443.1 - 0.093 12.4 0.0 0.34 10.6 0.0 2.0 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF362 PF04015.7 EGC35443.1 - 0.095 12.1 0.0 0.2 11.1 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF362) ABC_tran PF00005.22 EGC35443.1 - 0.12 12.6 5.5 0.3 11.4 3.3 2.0 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EGC35443.1 - 0.14 11.7 0.2 0.77 9.3 0.0 2.2 2 0 0 2 2 2 0 P-loop containing region of AAA domain MARVEL PF01284.18 EGC35444.1 - 0.00059 19.6 9.5 0.00082 19.2 6.6 1.2 1 0 0 1 1 1 1 Membrane-associating domain DUF4131 PF13567.1 EGC35444.1 - 0.49 9.7 3.2 0.96 8.8 1.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Ninjurin PF04923.7 EGC35444.1 - 0.69 9.6 6.3 33 4.2 4.4 2.5 1 1 0 1 1 1 0 Ninjurin TarH PF02203.10 EGC35444.1 - 0.73 9.6 4.0 5.8 6.7 0.1 2.5 2 1 0 2 2 2 0 Tar ligand binding domain homologue Claudin_2 PF13903.1 EGC35444.1 - 7.3 6.2 11.7 15 5.1 4.2 2.6 2 1 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Spectrin PF00435.16 EGC35445.1 - 0.077 13.2 1.4 0.3 11.3 0.1 2.1 2 0 0 2 2 2 0 Spectrin repeat DUF3671 PF12420.3 EGC35445.1 - 0.57 10.1 11.5 1.2 9.1 8.0 1.6 1 0 0 1 1 1 0 Protein of unknown function YvrJ PF12841.2 EGC35445.1 - 1.3 8.4 4.5 0.86 8.9 0.2 2.6 2 0 0 2 2 2 0 YvrJ protein family Str_synth PF03088.11 EGC35446.1 - 1e-16 60.6 0.9 1.3e-14 53.9 0.0 3.5 2 1 1 3 3 3 1 Strictosidine synthase SGL PF08450.7 EGC35446.1 - 3.2e-12 46.3 0.0 1.8e-11 43.9 0.0 2.0 1 1 1 2 2 2 2 SMP-30/Gluconolaconase/LRE-like region Arylesterase PF01731.15 EGC35446.1 - 2.5e-05 24.1 1.3 0.00053 19.9 0.0 3.3 4 0 0 4 4 4 1 Arylesterase NHL PF01436.16 EGC35446.1 - 4.1e-05 23.3 1.8 0.1 12.6 0.1 4.7 5 0 0 5 5 5 2 NHL repeat ABC_tran PF00005.22 EGC35447.1 - 1e-54 184.5 0.8 2.1e-26 92.8 0.0 2.5 2 0 0 2 2 2 2 ABC transporter ABC2_membrane_3 PF12698.2 EGC35447.1 - 1.2e-38 133.0 50.6 1.6e-23 83.2 19.5 2.3 2 0 0 2 2 2 2 ABC-2 family transporter protein AAA_21 PF13304.1 EGC35447.1 - 2.3e-13 50.7 0.5 5.9e-11 42.8 0.6 7.2 7 1 0 7 7 7 2 AAA domain SMC_N PF02463.14 EGC35447.1 - 7.9e-07 28.5 0.0 0.37 9.9 0.0 4.0 3 1 0 3 3 3 3 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC35447.1 - 6.4e-05 22.4 4.1 0.034 13.6 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SbcCD_C PF13558.1 EGC35447.1 - 0.0041 17.0 0.0 0.11 12.4 0.0 2.9 2 2 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGC35447.1 - 0.0048 16.0 0.6 2.2 7.4 0.0 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Mg_chelatase PF01078.16 EGC35447.1 - 0.063 12.4 0.0 20 4.2 0.0 3.6 4 0 0 4 4 4 0 Magnesium chelatase, subunit ChlI SRP54 PF00448.17 EGC35447.1 - 0.21 10.9 1.4 13 5.1 0.0 2.5 2 0 0 2 2 2 0 SRP54-type protein, GTPase domain Zeta_toxin PF06414.7 EGC35447.1 - 0.27 10.2 0.1 7.5 5.5 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin ABC2_membrane_4 PF12730.2 EGC35447.1 - 1 8.4 75.5 0.17 10.9 24.6 3.6 2 2 0 2 2 2 0 ABC-2 family transporter protein ABC2_membrane PF01061.19 EGC35447.1 - 7.5 5.6 43.9 0.24 10.5 10.4 3.6 3 1 0 3 3 3 0 ABC-2 type transporter OSCP PF00213.13 EGC35448.1 - 7.7e-15 55.1 0.1 2e-14 53.8 0.0 1.6 2 0 0 2 2 2 1 ATP synthase delta (OSCP) subunit ApoLp-III PF07464.6 EGC35448.1 - 0.083 12.9 0.9 0.37 10.8 0.2 2.2 2 0 0 2 2 2 0 Apolipophorin-III precursor (apoLp-III) FNIP PF05725.7 EGC35451.1 - 2.1e-24 85.1 20.9 1.6e-06 27.9 0.9 4.9 2 1 4 6 6 6 6 FNIP Repeat Serinc PF03348.10 EGC35452.1 - 2.6e-106 355.9 25.8 7.7e-106 354.3 17.9 1.6 1 1 0 1 1 1 1 Serine incorporator (Serinc) Prp19_bind PF06991.6 EGC35453.1 - 3.2e-32 111.9 10.3 3.2e-32 111.9 7.1 2.6 1 1 1 2 2 2 1 Splicing factor, Prp19-binding domain Profilin PF00235.14 EGC35454.1 - 0.003 17.6 0.0 0.0043 17.1 0.0 1.4 1 1 0 1 1 1 1 Profilin STAS PF01740.16 EGC35454.1 - 0.03 13.7 0.0 0.054 12.9 0.0 1.4 1 0 0 1 1 1 0 STAS domain DUF1084 PF06454.6 EGC35455.1 - 1.7e-11 43.6 24.7 7e-11 41.6 17.1 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) DUF726 PF05277.7 EGC35463.1 - 1.3e-67 228.2 0.7 1.3e-67 228.2 0.5 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF726) VPS9 PF02204.13 EGC35463.1 - 1e-12 48.0 2.8 1.4e-12 47.4 0.5 2.3 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain SH PF01445.12 EGC35463.1 - 0.097 12.3 0.3 0.24 11.0 0.2 1.6 1 0 0 1 1 1 0 Viral small hydrophobic protein RNA_pol_Rpc4 PF05132.9 EGC35465.1 - 1e-18 67.6 0.6 1e-18 67.6 0.4 2.9 3 1 0 3 3 3 1 RNA polymerase III RPC4 YtfJ_HI0045 PF09695.5 EGC35466.1 - 0.00084 18.7 1.5 0.0011 18.2 0.8 1.3 1 1 0 1 1 1 1 Bacterial protein of unknown function (YtfJ_HI0045) DUF438 PF04282.8 EGC35466.1 - 0.094 12.5 4.4 0.073 12.8 0.7 2.1 1 1 1 2 2 2 0 Family of unknown function (DUF438) DUF4342 PF14242.1 EGC35466.1 - 6.9 6.5 13.0 12 5.7 0.2 3.9 1 1 3 4 4 4 0 Domain of unknown function (DUF4342) Ras PF00071.17 EGC35467.1 - 1.1e-41 141.9 0.1 1.4e-41 141.5 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35467.1 - 3e-16 59.9 0.1 7.1e-16 58.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC35467.1 - 4.8e-15 55.2 0.1 9.9e-15 54.2 0.1 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC35467.1 - 2.9e-06 26.6 0.3 3.5e-06 26.3 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC35467.1 - 7.8e-06 25.2 0.1 2e-05 23.8 0.0 1.6 1 1 1 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC35467.1 - 0.0091 15.9 0.1 0.015 15.2 0.1 1.7 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_22 PF13401.1 EGC35467.1 - 0.055 13.6 0.1 6.9 6.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain Adaptin_N PF01602.15 EGC35468.1 - 5e-70 236.3 29.3 8e-70 235.6 20.3 1.3 1 0 0 1 1 1 1 Adaptin N terminal region HEAT_2 PF13646.1 EGC35468.1 - 3.7e-06 27.1 0.1 0.0056 16.9 0.0 3.8 3 0 0 3 3 3 1 HEAT repeats HEAT PF02985.17 EGC35468.1 - 0.00048 19.9 0.5 0.49 10.6 0.0 4.7 5 0 0 5 5 5 1 HEAT repeat Vac14_Fab1_bd PF12755.2 EGC35468.1 - 0.0014 18.9 0.9 0.41 11.0 0.1 2.8 2 0 0 2 2 2 2 Vacuolar 14 Fab1-binding region RIO1 PF01163.17 EGC35469.1 - 1.1e-76 256.4 0.7 1.1e-76 256.4 0.5 1.6 2 0 0 2 2 2 1 RIO1 family TetR_C_2 PF08361.6 EGC35469.1 - 0.023 14.6 1.1 0.82 9.6 0.1 2.5 2 0 0 2 2 2 0 MAATS-type transcriptional repressor, C-terminal region APH PF01636.18 EGC35469.1 - 0.03 14.0 0.0 2.8 7.6 0.0 2.3 1 1 1 2 2 2 0 Phosphotransferase enzyme family CDC45 PF02724.9 EGC35469.1 - 0.11 10.5 17.3 0.2 9.6 12.0 1.4 1 0 0 1 1 1 0 CDC45-like protein Kdo PF06293.9 EGC35469.1 - 0.34 9.9 3.1 0.71 8.8 0.0 2.6 3 0 0 3 3 3 0 Lipopolysaccharide kinase (Kdo/WaaP) family Dynactin PF12455.3 EGC35470.1 - 5.6e-53 179.6 11.7 5.6e-53 179.6 8.1 6.2 5 1 1 7 7 7 2 Dynein associated protein CAP_GLY PF01302.20 EGC35470.1 - 1.3e-22 79.2 0.1 2.2e-22 78.5 0.1 1.3 1 0 0 1 1 1 1 CAP-Gly domain Ras PF00071.17 EGC35471.1 - 2.2e-57 192.9 0.0 2.8e-57 192.6 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35471.1 - 8.6e-18 64.9 0.0 1.8e-17 63.9 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC35471.1 - 2e-12 46.7 0.0 2.5e-12 46.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC35471.1 - 2e-05 24.0 0.0 3.1e-05 23.4 0.0 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Voldacs PF03517.8 EGC35471.1 - 0.0055 16.5 0.4 0.0068 16.2 0.3 1.3 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Septin PF00735.13 EGC35471.1 - 0.0086 15.1 0.6 0.2 10.6 0.0 2.8 2 1 2 4 4 4 1 Septin AAA_22 PF13401.1 EGC35471.1 - 0.01 15.9 0.0 0.1 12.7 0.0 2.4 2 1 0 2 2 2 0 AAA domain SEN1_N PF12726.2 EGC35471.1 - 0.018 13.1 0.0 0.023 12.7 0.0 1.1 1 0 0 1 1 1 0 SEN1 N terminal MMR_HSR1 PF01926.18 EGC35471.1 - 0.026 14.4 0.0 0.052 13.4 0.0 1.5 1 1 0 1 1 1 0 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC35471.1 - 0.04 13.1 0.0 0.099 11.9 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B AAA_10 PF12846.2 EGC35471.1 - 0.063 12.7 0.0 0.089 12.2 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_14 PF13173.1 EGC35471.1 - 0.082 12.8 0.1 0.26 11.1 0.1 1.9 1 1 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC35471.1 - 0.092 12.7 0.0 0.67 9.9 0.0 2.0 2 0 0 2 2 2 0 AAA ATPase domain SR-25 PF10500.4 EGC35472.1 - 0.89 8.9 9.4 2.2 7.7 6.5 1.6 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pox_E10 PF04805.7 EGC35473.1 - 0.075 12.5 0.9 0.15 11.6 0.6 1.4 1 0 0 1 1 1 0 E10-like protein conserved region DCAF15_WD40 PF14939.1 EGC35473.1 - 0.12 11.6 0.5 0.1 11.9 0.4 1.1 1 0 0 1 1 1 0 DDB1-and CUL4-substrate receptor 15, WD repeat PH PF00169.24 EGC35474.1 - 1.5e-27 95.7 13.2 2.5e-14 53.3 0.2 3.3 3 1 0 3 3 3 2 PH domain FHA PF00498.21 EGC35474.1 - 6.5e-18 64.6 3.6 1.5e-17 63.4 0.8 2.8 3 0 0 3 3 3 1 FHA domain PH_11 PF15413.1 EGC35474.1 - 2.3e-09 37.4 18.3 5.8e-06 26.5 0.3 5.1 2 2 1 3 3 3 2 Pleckstrin homology domain PH_8 PF15409.1 EGC35474.1 - 5.4e-09 36.0 2.8 0.00016 21.6 1.0 3.2 2 1 0 2 2 2 2 Pleckstrin homology domain PH_9 PF15410.1 EGC35474.1 - 0.00022 21.3 0.9 2.8 8.1 0.0 3.6 2 1 0 2 2 2 2 Pleckstrin homology domain PH_3 PF14593.1 EGC35474.1 - 0.0012 18.7 5.2 0.27 11.1 0.5 2.8 2 1 0 2 2 2 2 PH domain DSHCT PF08148.7 EGC35475.1 - 1.4e-55 187.3 0.2 3.7e-55 185.9 0.2 1.8 1 0 0 1 1 1 1 DSHCT (NUC185) domain rRNA_proc-arch PF13234.1 EGC35475.1 - 3.4e-22 78.8 8.5 1.3e-19 70.3 5.9 2.6 1 1 0 1 1 1 1 rRNA-processing arch domain DEAD PF00270.24 EGC35475.1 - 3.9e-19 68.7 0.0 1.4e-18 67.0 0.0 2.0 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC35475.1 - 1.8e-05 24.5 0.0 8.7e-05 22.3 0.0 2.3 1 1 0 1 1 1 1 Helicase conserved C-terminal domain CENP-T PF15511.1 EGC35475.1 - 1 8.5 8.3 1.5 7.9 5.7 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Beta-lactamase PF00144.19 EGC35476.1 - 1e-30 106.8 0.0 1.3e-30 106.5 0.0 1.1 1 0 0 1 1 1 1 Beta-lactamase Peptidase_S11 PF00768.15 EGC35476.1 - 0.053 12.7 0.0 0.11 11.7 0.0 1.5 1 0 0 1 1 1 0 D-alanyl-D-alanine carboxypeptidase FNIP PF05725.7 EGC35477.1 - 6.1e-52 173.3 71.7 1.9e-10 40.5 2.1 13.5 9 2 2 13 13 13 11 FNIP Repeat zf-B_box PF00643.19 EGC35477.1 - 1.8e-07 30.8 3.5 3.2e-07 30.1 2.4 1.4 1 0 0 1 1 1 1 B-box zinc finger Abhydro_lipase PF04083.11 EGC35478.1 - 9.5e-19 66.5 1.3 3.2e-18 64.8 0.9 1.9 1 1 0 1 1 1 1 Partial alpha/beta-hydrolase lipase region Abhydrolase_1 PF00561.15 EGC35478.1 - 2.9e-09 36.8 0.0 4.8e-09 36.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC35478.1 - 6.3e-07 29.5 0.0 1e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC35478.1 - 2.5e-06 27.3 0.0 3.5e-06 26.8 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peripla_BP_6 PF13458.1 EGC35478.1 - 0.031 13.6 0.0 0.052 12.8 0.0 1.3 1 0 0 1 1 1 0 Periplasmic binding protein Pap_E4 PF02711.9 EGC35478.1 - 0.084 13.6 3.7 0.14 12.9 2.6 1.4 1 0 0 1 1 1 0 E4 protein THF_DHG_CYH PF00763.18 EGC35479.1 - 1.5e-15 57.2 0.0 2.8e-15 56.3 0.0 1.4 1 0 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain THF_DHG_CYH_C PF02882.14 EGC35479.1 - 2.3e-15 56.0 0.6 9.4e-13 47.5 0.4 3.2 1 1 0 1 1 1 1 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain Urocanase PF01175.13 EGC35480.1 - 8.2e-221 733.7 0.2 1e-220 733.4 0.2 1.0 1 0 0 1 1 1 1 Urocanase ETC_C1_NDUFA4 PF04800.7 EGC35481.1 - 6.7e-24 83.6 0.0 9.7e-24 83.1 0.0 1.2 1 0 0 1 1 1 1 ETC complex I subunit conserved region SET PF00856.23 EGC35483.1 - 9.3e-08 32.5 5.1 1.7e-06 28.4 3.5 2.4 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGC35483.1 - 0.0015 18.3 11.3 0.0015 18.3 7.8 3.4 3 1 0 3 3 3 1 MYND finger Beta-lactamase2 PF13354.1 EGC35483.1 - 0.026 13.9 0.3 0.21 11.0 0.0 2.1 1 1 0 2 2 2 0 Beta-lactamase enzyme family Desulfoferrod_N PF06397.7 EGC35483.1 - 0.46 9.9 8.3 1.8 8.0 0.7 2.5 2 0 0 2 2 2 0 Desulfoferrodoxin, N-terminal domain DUF3133 PF11331.3 EGC35483.1 - 4.9 6.7 10.2 1.2 8.8 3.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF3133) Rad51 PF08423.6 EGC35484.1 - 6.2e-41 139.9 1.2 1.9e-22 79.4 0.0 2.2 1 1 1 2 2 2 2 Rad51 HHH_5 PF14520.1 EGC35484.1 - 1.3e-09 38.1 0.9 4.3e-09 36.4 0.2 2.1 2 1 1 3 3 3 1 Helix-hairpin-helix domain Coatomer_E PF04733.9 EGC35484.1 - 0.0021 17.3 0.4 0.0027 16.9 0.3 1.2 1 0 0 1 1 1 1 Coatomer epsilon subunit HHH PF00633.18 EGC35484.1 - 0.006 16.2 0.1 0.021 14.5 0.0 2.0 2 0 0 2 2 2 1 Helix-hairpin-helix motif KaiC PF06745.8 EGC35484.1 - 0.07 12.2 0.4 0.07 12.2 0.3 1.8 2 0 0 2 2 2 0 KaiC Pur_DNA_glyco PF02245.11 EGC35485.1 - 0.0072 15.4 0.0 0.011 14.8 0.0 1.2 1 0 0 1 1 1 1 Methylpurine-DNA glycosylase (MPG) EGF_2 PF07974.8 EGC35485.1 - 4.6 7.4 12.7 1.9 8.7 5.9 2.6 2 0 0 2 2 2 0 EGF-like domain DUF3430 PF11912.3 EGC35486.1 - 1.6e-14 54.2 23.2 1.9e-14 54.0 16.1 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) zf-CCHC PF00098.18 EGC35487.1 - 0.053 13.4 20.9 0.045 13.7 1.8 3.7 3 1 0 3 3 3 0 Zinc knuckle zf-CCHC_3 PF13917.1 EGC35487.1 - 1.6 8.5 18.5 0.091 12.5 0.5 3.5 1 1 2 3 3 3 0 Zinc knuckle LNS2 PF08235.8 EGC35488.1 - 1.8e-60 203.0 0.7 2.3e-59 199.4 0.5 2.2 1 1 0 1 1 1 1 LNS2 (Lipin/Ned1/Smp2) Lipin_N PF04571.9 EGC35488.1 - 2.9e-36 123.4 0.0 7e-36 122.2 0.0 1.7 1 0 0 1 1 1 1 lipin, N-terminal conserved region DUF4407 PF14362.1 EGC35488.1 - 0.085 11.7 1.5 0.14 11.1 1.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF3488 PF11992.3 EGC35488.1 - 0.11 11.1 1.7 0.17 10.4 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3488) Asparaginase PF00710.15 EGC35489.1 - 1.8e-110 368.7 0.0 2.1e-110 368.4 0.0 1.0 1 0 0 1 1 1 1 Asparaginase EF-hand_1 PF00036.27 EGC35490.1 - 1.1e-14 52.4 4.7 3.2e-07 29.1 0.1 3.4 3 0 0 3 3 3 2 EF hand EF-hand_7 PF13499.1 EGC35490.1 - 2.2e-13 50.1 0.1 7.1e-13 48.4 0.1 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_8 PF13833.1 EGC35490.1 - 1.7e-11 43.5 2.0 5.6e-06 25.8 0.0 3.1 3 1 1 4 4 4 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC35490.1 - 3.3e-11 42.0 1.7 6.9e-06 25.5 0.0 3.5 4 0 0 4 4 4 2 EF-hand domain EF-hand_5 PF13202.1 EGC35490.1 - 5.9e-11 41.1 0.3 1e-06 27.7 0.1 2.7 2 0 0 2 2 2 2 EF hand WWE PF02825.15 EGC35490.1 - 1.5e-06 27.5 0.5 3.8e-06 26.2 0.3 1.7 1 0 0 1 1 1 1 WWE domain EF-hand_9 PF14658.1 EGC35490.1 - 1.7e-05 24.6 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 EF-hand domain SPARC_Ca_bdg PF10591.4 EGC35490.1 - 7.6e-05 22.7 0.0 0.00025 21.0 0.0 1.9 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC35490.1 - 0.1 12.2 0.1 7.8 6.2 0.0 2.9 2 0 0 2 2 2 0 EF hand Menin PF05053.8 EGC35490.1 - 0.2 9.7 2.4 0.31 9.1 1.7 1.2 1 0 0 1 1 1 0 Menin GST_C PF00043.20 EGC35491.1 - 6.6e-13 48.4 0.0 1.3e-12 47.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC35491.1 - 4.9e-11 42.6 0.0 9.2e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC35491.1 - 8.1e-11 41.6 0.0 1.3e-10 40.9 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC35491.1 - 5e-09 36.0 0.0 1.1e-08 34.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC35491.1 - 1.3e-05 25.2 0.0 2.4e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC35491.1 - 5.2e-05 23.6 0.0 7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain DUF4085 PF13315.1 EGC35491.1 - 0.052 12.9 0.1 0.099 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4085) Abhydrolase_5 PF12695.2 EGC35492.1 - 1.5e-16 60.4 0.0 2.1e-16 59.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC35492.1 - 1e-15 58.2 0.0 1.3e-15 57.9 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC35492.1 - 4.7e-07 29.2 0.1 0.0016 17.7 0.0 2.3 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGC35492.1 - 0.00022 20.7 0.0 0.19 11.1 0.1 2.8 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase Abhydrolase_1 PF00561.15 EGC35492.1 - 0.0003 20.4 0.1 0.13 11.8 0.0 2.2 2 0 0 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EGC35492.1 - 0.0023 16.5 0.2 1.2 7.5 0.0 2.9 2 1 0 2 2 2 1 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EGC35492.1 - 0.0051 16.2 0.2 0.049 13.0 0.1 2.0 2 0 0 2 2 2 1 X-Pro dipeptidyl-peptidase (S15 family) Abhydrolase_4 PF08386.5 EGC35492.1 - 0.0098 15.7 0.1 0.018 14.8 0.0 1.4 1 0 0 1 1 1 1 TAP-like protein Tannase PF07519.6 EGC35492.1 - 0.028 13.1 0.1 0.56 8.8 0.0 2.1 2 0 0 2 2 2 0 Tannase and feruloyl esterase Lipase_3 PF01764.20 EGC35492.1 - 0.094 12.3 0.0 0.18 11.3 0.0 1.5 1 0 0 1 1 1 0 Lipase (class 3) Histone PF00125.19 EGC35493.1 - 6.2e-24 83.9 3.0 1.3e-11 44.4 0.1 2.1 2 0 0 2 2 2 2 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC35493.1 - 1.8e-08 34.2 1.2 0.0002 21.3 0.2 2.2 2 0 0 2 2 2 2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGC35493.1 - 0.00054 20.1 1.3 0.008 16.4 0.1 2.3 2 1 0 2 2 2 1 Transcription initiation factor TFIID subunit A DUF1741 PF08427.5 EGC35493.1 - 0.001 18.5 1.8 0.0027 17.2 0.3 1.9 1 1 1 2 2 2 1 Domain of unknown function (DUF1741) TAF PF02969.12 EGC35493.1 - 0.038 13.9 0.8 3.5 7.6 0.1 2.5 2 0 0 2 2 2 0 TATA box binding protein associated factor (TAF) TFIID-18kDa PF02269.11 EGC35493.1 - 0.048 13.4 0.9 0.25 11.1 0.0 2.1 2 1 0 2 2 2 0 Transcription initiation factor IID, 18kD subunit UQ_con PF00179.21 EGC35494.1 - 1.8e-35 121.4 0.0 1.9e-35 121.2 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC35494.1 - 1.5e-05 24.7 0.0 1.7e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC35494.1 - 0.11 12.3 0.3 0.12 12.3 0.2 1.4 1 1 0 1 1 1 0 RWD domain Glyco_transf_49 PF13896.1 EGC35495.1 - 1e-45 156.2 0.7 4.9e-37 127.7 0.0 2.1 1 1 1 2 2 2 2 Glycosyl-transferase for dystroglycan Coiled PF05710.7 EGC35495.1 - 1.3e-12 47.9 23.6 1.3e-12 47.9 16.3 1.8 2 0 0 2 2 2 1 Coiled coil Glyco_tranf_2_2 PF10111.4 EGC35495.1 - 0.00035 19.7 0.1 0.00086 18.4 0.1 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_2 PF00535.21 EGC35495.1 - 0.016 14.9 0.0 0.028 14.1 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 2 IPK PF03770.11 EGC35496.1 - 9.3e-38 129.8 1.8 9.8e-38 129.7 0.1 1.8 2 0 0 2 2 2 1 Inositol polyphosphate kinase 7tm_3 PF00003.17 EGC35497.1 - 2.1e-37 128.7 20.6 3.8e-37 127.9 14.3 1.4 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC35497.1 - 1.5e-19 69.8 0.8 1.5e-19 69.8 0.5 1.6 2 0 0 2 2 2 1 Basic membrane protein 7tm_3 PF00003.17 EGC35498.1 - 5.3e-38 130.7 19.9 7.9e-38 130.1 13.8 1.2 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Bmp PF02608.9 EGC35498.1 - 2e-16 59.6 3.4 2e-16 59.6 2.4 1.7 2 0 0 2 2 2 1 Basic membrane protein Rb_C PF08934.5 EGC35498.1 - 0.017 14.7 1.1 0.055 13.0 0.9 1.7 2 0 0 2 2 2 0 Rb C-terminal domain DUF2140 PF09911.4 EGC35498.1 - 0.033 13.3 0.4 0.033 13.3 0.3 2.2 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2140) NIF PF03031.13 EGC35499.1 - 3.9e-29 101.3 1.8 3.9e-29 101.3 1.3 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase PTCB-BRCT PF12738.2 EGC35499.1 - 7.2e-13 48.1 0.0 1.6e-12 47.0 0.0 1.6 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGC35499.1 - 5.5e-12 45.6 0.1 3.1e-11 43.2 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Biotin_lipoyl PF00364.17 EGC35499.1 - 0.032 13.8 0.0 0.064 12.9 0.0 1.5 1 0 0 1 1 1 0 Biotin-requiring enzyme DUF966 PF06136.8 EGC35499.1 - 4.8 6.5 40.2 0.21 10.9 10.2 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF966) Peptidase_S49_N PF08496.5 EGC35499.1 - 8.2 6.1 10.9 30 4.3 7.6 2.0 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Coiled PF05710.7 EGC35500.1 - 1.9e-16 60.3 20.0 2.3e-16 60.0 13.9 1.0 1 0 0 1 1 1 1 Coiled coil Sclerostin PF05463.6 EGC35500.1 - 0.1 12.1 0.2 0.12 11.8 0.1 1.1 1 0 0 1 1 1 0 Sclerostin (SOST) DUF1517 PF07466.6 EGC35500.1 - 2.1 7.2 4.7 2.3 7.1 3.2 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) DUF4266 PF14086.1 EGC35500.1 - 8.4 6.9 16.4 3.7 8.1 2.2 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) DUF4211 PF13926.1 EGC35501.1 - 2.8e-36 124.2 4.4 2.8e-36 124.2 3.0 4.3 5 0 0 5 5 5 1 Domain of unknown function (DUF4211) SH3_9 PF14604.1 EGC35502.1 - 6.2e-29 99.3 2.2 1.1e-13 50.4 0.3 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_1 PF00018.23 EGC35502.1 - 1.9e-22 78.3 1.4 8.2e-14 50.7 0.0 2.4 2 0 0 2 2 2 2 SH3 domain SH3_2 PF07653.12 EGC35502.1 - 2.8e-21 74.7 0.3 5.7e-11 41.7 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain FCH PF00611.18 EGC35502.1 - 3.5e-13 49.5 1.0 3.5e-13 49.5 0.7 2.2 2 1 0 2 2 2 1 Fes/CIP4, and EFC/F-BAR homology domain DUF4407 PF14362.1 EGC35502.1 - 6.8 5.5 8.2 9.8 5.0 5.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) PEPCK_ATP PF01293.15 EGC35503.1 - 7.5e-219 727.0 0.0 8.8e-219 726.7 0.0 1.0 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxykinase AAA_33 PF13671.1 EGC35503.1 - 0.0022 17.9 0.0 0.0039 17.0 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC35503.1 - 0.016 15.1 0.0 0.031 14.2 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_17 PF13207.1 EGC35503.1 - 0.058 14.2 0.1 0.37 11.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGC35503.1 - 0.087 12.3 0.0 0.23 10.9 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain EGF_2 PF07974.8 EGC35504.1 - 0.47 10.6 11.8 1 9.5 8.2 1.5 1 0 0 1 1 1 0 EGF-like domain Toxin_5 PF05294.8 EGC35504.1 - 2.9 8.1 7.0 6.3 7.0 4.8 1.6 1 0 0 1 1 1 0 Scorpion short toxin p450 PF00067.17 EGC35505.1 - 5.4e-100 335.1 0.0 6.2e-100 334.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 UCR_hinge PF02320.11 EGC35506.1 - 2.5e-17 62.5 2.2 3e-17 62.2 1.5 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase hinge protein CHCH PF06747.8 EGC35506.1 - 0.38 10.7 5.8 4.2 7.4 0.2 2.5 2 0 0 2 2 2 0 CHCH domain UPF0203 PF05254.7 EGC35506.1 - 0.63 9.9 7.1 2.1 8.2 1.8 2.1 1 1 1 2 2 2 0 Uncharacterised protein family (UPF0203) GCK PF07802.6 EGC35506.1 - 0.86 9.7 3.9 1.2 9.3 2.7 1.2 1 0 0 1 1 1 0 GCK domain Toxin_13 PF07822.6 EGC35506.1 - 3.1 7.8 6.3 7.8 6.4 4.4 1.8 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein DUF1168 PF06658.7 EGC35507.1 - 5.7e-30 103.6 27.5 7e-30 103.4 19.1 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1168) TFIIA PF03153.8 EGC35507.1 - 0.062 13.1 23.8 0.065 13.1 16.5 1.0 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit ATG27 PF09451.5 EGC35507.1 - 0.69 9.0 12.5 0.99 8.5 8.7 1.3 1 0 0 1 1 1 0 Autophagy-related protein 27 Daxx PF03344.10 EGC35507.1 - 1.2 7.5 28.2 1.5 7.2 19.6 1.0 1 0 0 1 1 1 0 Daxx Family Tfb2 PF03849.9 EGC35507.1 - 3 6.3 9.5 3.9 6.0 6.6 1.1 1 0 0 1 1 1 0 Transcription factor Tfb2 FLO_LFY PF01698.11 EGC35507.1 - 3.1 6.5 18.8 3.4 6.4 13.0 1.1 1 0 0 1 1 1 0 Floricaula / Leafy protein Myc_N PF01056.13 EGC35509.1 - 0.082 12.0 4.1 0.13 11.4 2.9 1.2 1 0 0 1 1 1 0 Myc amino-terminal region dCMP_cyt_deam_1 PF00383.17 EGC35510.1 - 2.4e-15 56.0 0.1 3.9e-15 55.3 0.0 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC35510.1 - 0.016 15.0 0.2 0.94 9.3 0.1 2.2 1 1 0 1 1 1 0 Bd3614-like deaminase zf-FPG_IleRS PF06827.9 EGC35510.1 - 0.11 12.1 0.7 2.1 8.0 0.0 2.4 2 0 0 2 2 2 0 Zinc finger found in FPG and IleRS Lar_restr_allev PF14354.1 EGC35510.1 - 0.11 12.8 0.1 0.2 11.9 0.1 1.5 1 0 0 1 1 1 0 Restriction alleviation protein Lar dCMP_cyt_deam_1 PF00383.17 EGC35511.1 - 1.1e-16 60.2 0.1 2.1e-16 59.4 0.1 1.4 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC35511.1 - 9.8e-06 25.4 1.2 0.0003 20.6 0.8 2.1 1 1 0 1 1 1 1 Bd3614-like deaminase Coiled PF05710.7 EGC35512.1 - 3.3e-15 56.3 15.5 4.1e-15 56.0 10.7 1.0 1 0 0 1 1 1 1 Coiled coil Chlorosome_CsmC PF11098.3 EGC35512.1 - 1.5 8.4 4.9 2.4 7.8 3.4 1.3 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF4266 PF14086.1 EGC35512.1 - 4.8 7.7 11.7 7.7 7.1 0.3 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4266) MATH PF00917.21 EGC35513.1 - 1.9e-39 134.5 37.6 1.7e-14 54.0 1.9 5.5 6 0 0 6 6 6 4 MATH domain USP7_ICP0_bdg PF12436.3 EGC35513.1 - 1.5e-30 106.2 0.3 4.6e-30 104.6 0.2 1.8 1 0 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 DUF3439 PF11921.3 EGC35513.1 - 0.016 14.9 11.3 0.036 13.8 7.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC35513.1 - 0.84 9.3 21.1 1.5 8.5 14.6 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein UQ_con PF00179.21 EGC35514.1 - 2.8e-28 98.1 0.7 7.6e-26 90.2 0.0 3.2 2 1 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGC35514.1 - 0.0091 15.6 0.1 0.054 13.1 0.0 2.3 3 0 0 3 3 3 1 UEV domain YlqD PF11068.3 EGC35514.1 - 0.39 10.7 12.3 1.3 9.0 0.3 3.4 3 0 0 3 3 3 0 YlqD protein CENP-F_leu_zip PF10473.4 EGC35515.1 - 9.6e-07 28.7 24.1 9.6e-07 28.7 16.7 10.8 1 1 8 10 10 10 4 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EGC35515.1 - 1.6e-05 22.9 101.6 1.6e-05 22.9 70.4 4.1 1 1 3 4 4 4 2 Myosin tail Filament PF00038.16 EGC35515.1 - 0.00039 19.9 59.4 0.00039 19.9 41.2 5.7 1 1 4 5 5 5 1 Intermediate filament protein ATG16 PF08614.6 EGC35515.1 - 0.0021 17.8 23.3 0.0021 17.8 16.1 8.2 1 1 7 8 8 8 3 Autophagy protein 16 (ATG16) IncA PF04156.9 EGC35515.1 - 0.0097 15.5 29.2 0.0097 15.5 20.2 8.8 1 1 7 8 8 8 2 IncA protein Reo_sigmaC PF04582.7 EGC35515.1 - 0.76 8.8 67.9 0.49 9.5 3.3 6.5 1 1 6 7 7 7 0 Reovirus sigma C capsid protein Polyketide_cyc PF03364.15 EGC35516.1 - 4.2e-22 78.5 0.0 5.2e-22 78.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport Patatin PF01734.17 EGC35517.1 - 3.8e-15 56.3 1.3 1.5e-14 54.4 0.9 1.8 1 1 0 1 1 1 1 Patatin-like phospholipase HTH_WhiA PF02650.9 EGC35517.1 - 0.072 13.4 0.0 0.17 12.3 0.0 1.5 1 0 0 1 1 1 0 WhiA C-terminal HTH domain DUF2470 PF10615.4 EGC35518.1 - 0.00099 19.2 0.0 0.0022 18.1 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF2470) Acyltransferase PF01553.16 EGC35520.1 - 2.3e-15 56.2 0.1 4.5e-15 55.2 0.1 1.5 1 0 0 1 1 1 1 Acyltransferase PROCN PF08083.6 EGC35521.1 - 4.7e-217 720.2 10.1 7.2e-217 719.6 7.0 1.3 1 0 0 1 1 1 1 PROCN (NUC071) domain PRP8_domainIV PF12134.3 EGC35521.1 - 2.7e-124 412.9 1.0 5.5e-124 411.9 0.7 1.6 1 0 0 1 1 1 1 PRP8 domain IV core U6-snRNA_bdg PF10596.4 EGC35521.1 - 8e-93 308.0 2.2 1.8e-92 306.9 1.5 1.7 1 0 0 1 1 1 1 U6-snRNA interacting domain of PrP8 PRO8NT PF08082.6 EGC35521.1 - 1e-81 272.0 4.7 2.5e-81 270.7 3.3 1.7 1 0 0 1 1 1 1 PRO8NT (NUC069), PrP8 N-terminal domain U5_2-snRNA_bdg PF10597.4 EGC35521.1 - 8e-68 226.2 0.1 1.6e-67 225.3 0.1 1.5 1 0 0 1 1 1 1 U5-snRNA binding site 2 of PrP8 PROCT PF08084.6 EGC35521.1 - 2.2e-45 153.4 1.3 8.3e-45 151.5 1.0 2.0 2 0 0 2 2 2 1 PROCT (NUC072) domain RRM_4 PF10598.4 EGC35521.1 - 6.2e-43 144.5 0.3 2e-42 142.9 0.2 2.0 1 0 0 1 1 1 1 RNA recognition motif of the spliceosomal PrP8 JAB PF01398.16 EGC35521.1 - 6.9e-08 32.2 0.0 1.9e-07 30.8 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Ank_2 PF12796.2 EGC35522.1 - 0.032 14.5 1.9 0.92 9.8 0.2 3.2 2 1 0 2 2 2 0 Ankyrin repeats (3 copies) FNIP PF05725.7 EGC35523.1 - 9.7e-48 159.8 41.2 1.2e-11 44.3 1.5 7.8 4 2 5 9 9 9 9 FNIP Repeat FNIP PF05725.7 EGC35524.1 - 7.6e-53 176.2 44.3 1.2e-10 41.1 2.0 8.9 4 2 5 9 9 9 9 FNIP Repeat HCaRG PF07258.9 EGC35525.1 - 1.4e-30 106.1 0.4 1.9e-30 105.7 0.3 1.1 1 0 0 1 1 1 1 HCaRG protein 60KD_IMP PF02096.15 EGC35525.1 - 0.021 14.4 0.3 0.027 14.1 0.2 1.2 1 0 0 1 1 1 0 60Kd inner membrane protein PFK PF00365.15 EGC35526.1 - 1.6e-174 578.5 0.1 5.8e-114 379.8 0.2 2.1 2 0 0 2 2 2 2 Phosphofructokinase Myb_DNA-binding PF00249.26 EGC35527.1 - 8.1e-14 51.4 0.2 1.4e-13 50.6 0.1 1.4 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC35527.1 - 1e-05 25.5 0.4 1e-05 25.5 0.3 2.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain adh_short PF00106.20 EGC35528.1 - 5.1e-21 75.2 0.0 7.2e-21 74.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC35528.1 - 9.1e-14 51.8 0.0 1.2e-13 51.3 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC35528.1 - 6.8e-06 25.8 0.0 1.1e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC35528.1 - 0.00043 19.5 0.0 0.00094 18.3 0.0 1.6 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC35528.1 - 0.0066 16.4 0.0 0.035 14.1 0.0 2.0 2 0 0 2 2 2 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC35528.1 - 0.035 12.9 0.0 0.062 12.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain DUF478 PF04334.7 EGC35528.1 - 0.11 12.3 0.0 0.26 11.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF478) CLTH PF10607.4 EGC35530.1 - 9.3e-31 106.4 2.1 9.3e-31 106.4 1.5 1.9 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGC35530.1 - 1.5e-17 62.9 3.6 5.2e-17 61.2 2.5 2.0 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_2 PF13923.1 EGC35530.1 - 1.4e-06 28.1 1.1 3.1e-06 27.1 0.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC35530.1 - 1.1e-05 25.0 1.6 1.9e-05 24.2 1.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC35530.1 - 1.5e-05 24.5 1.4 2.8e-05 23.7 1.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC35530.1 - 2.5e-05 24.0 1.2 6.2e-05 22.7 0.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_2 PF13639.1 EGC35530.1 - 6.6e-05 22.6 1.8 0.00013 21.7 1.3 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC35530.1 - 9.7e-05 21.9 2.5 0.00021 20.8 1.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Rtf2 PF04641.7 EGC35530.1 - 0.026 13.7 0.3 0.026 13.7 0.2 1.8 2 0 0 2 2 2 0 Rtf2 RING-finger TFIID_90kDa PF04494.10 EGC35530.1 - 0.036 14.1 1.5 0.12 12.3 1.0 1.8 1 0 0 1 1 1 0 WD40 associated region in TFIID subunit Aminotran_1_2 PF00155.16 EGC35531.1 - 1.2e-46 159.3 0.0 1.5e-46 159.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGC35531.1 - 0.021 14.0 0.0 0.034 13.2 0.0 1.3 1 0 0 1 1 1 0 Beta-eliminating lyase DUF2232 PF09991.4 EGC35531.1 - 0.071 12.0 0.0 0.11 11.4 0.0 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Arrestin_C PF02752.17 EGC35532.1 - 4.3e-17 62.4 8.6 3.5e-15 56.3 0.4 2.3 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain C2 PF00168.25 EGC35532.1 - 5.2e-17 61.4 0.0 1.3e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain Arrestin_N PF00339.24 EGC35532.1 - 1.1e-13 51.2 1.5 4.2e-10 39.6 0.2 3.1 2 1 1 3 3 3 2 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.25 EGC35532.1 - 0.0031 17.6 0.3 0.0063 16.6 0.2 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) LDB19 PF13002.2 EGC35532.1 - 0.047 13.1 1.8 0.24 10.8 0.0 2.8 3 1 0 3 3 3 0 Arrestin_N terminal like YhdB PF14148.1 EGC35532.1 - 0.058 13.1 0.2 0.17 11.6 0.1 1.7 1 0 0 1 1 1 0 YhdB-like protein Ig_2 PF13895.1 EGC35532.1 - 0.07 13.2 0.1 0.15 12.1 0.0 1.5 1 0 0 1 1 1 0 Immunoglobulin domain zf-RING_2 PF13639.1 EGC35533.1 - 1.3e-08 34.4 9.0 2.3e-08 33.7 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC35533.1 - 3.1e-07 29.9 12.3 8.4e-07 28.5 8.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC35533.1 - 3.8e-06 26.4 8.1 6.4e-06 25.7 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC35533.1 - 1.7e-05 24.7 11.3 3.7e-05 23.6 7.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC35533.1 - 4.1e-05 23.6 5.0 0.00014 21.9 3.5 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC35533.1 - 0.0033 17.2 9.8 0.0073 16.1 6.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC35533.1 - 0.0045 16.6 10.2 0.0089 15.7 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC35533.1 - 0.026 14.0 8.7 0.054 13.0 6.1 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC35533.1 - 0.21 11.3 7.3 0.79 9.4 5.1 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_3 PF14369.1 EGC35533.1 - 0.41 10.6 5.9 1.2 9.1 4.1 1.8 1 0 0 1 1 1 0 zinc-finger DUF1272 PF06906.6 EGC35533.1 - 0.81 9.5 6.9 1.7 8.5 4.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) IBR PF01485.16 EGC35533.1 - 4.3 7.2 10.4 41 4.1 6.8 2.6 1 1 1 2 2 2 0 IBR domain Tcf25 PF04910.9 EGC35534.1 - 5e-92 308.6 9.5 5e-92 308.6 6.6 1.6 2 0 0 2 2 2 1 Transcriptional repressor TCF25 TFIIE-A_C-term PF11521.3 EGC35534.1 - 0.071 13.0 0.1 0.071 13.0 0.0 4.4 3 1 1 4 4 4 0 C-terminal general transcription factor TFIIE alpha Nucleoside_tran PF01733.13 EGC35534.1 - 5 6.1 7.7 0.37 9.8 0.6 2.2 2 0 0 2 2 2 0 Nucleoside transporter Syja_N PF02383.13 EGC35535.1 - 5.9e-87 291.3 7.0 1.8e-86 289.7 4.8 1.9 1 0 0 1 1 1 1 SacI homology domain hSac2 PF12456.3 EGC35535.1 - 1.1e-26 92.5 0.3 2.7e-26 91.2 0.2 1.7 1 0 0 1 1 1 1 Inositol phosphatase DUF4231 PF14015.1 EGC35537.1 - 2 8.4 7.1 15 5.6 4.9 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF4231) Tetraspannin PF00335.15 EGC35537.1 - 5 6.3 27.3 94 2.1 19.0 2.5 1 1 0 1 1 1 0 Tetraspanin family Acetyltransf_2 PF00797.12 EGC35538.1 - 1.1e-31 110.2 0.0 2.5e-31 109.0 0.0 1.5 1 1 0 1 1 1 1 N-acetyltransferase LisH PF08513.6 EGC35538.1 - 0.023 14.4 1.5 0.03 14.0 0.1 2.0 2 0 0 2 2 2 0 LisH RCC1_2 PF13540.1 EGC35539.1 - 6.4e-28 95.7 3.9 6.4e-08 32.0 0.0 6.4 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGC35539.1 - 5.1e-27 93.8 4.7 2.9e-09 36.9 0.1 6.5 6 0 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat OTU PF02338.14 EGC35540.1 - 1.1e-13 51.8 0.1 2.8e-13 50.5 0.1 1.7 1 0 0 1 1 1 1 OTU-like cysteine protease PAT1 PF09770.4 EGC35540.1 - 1.4 7.0 60.7 2.4 6.2 42.0 1.3 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGC35540.1 - 5.2 6.8 40.9 7.7 6.3 28.3 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit DUF605 PF04652.11 EGC35540.1 - 7.1 5.9 52.4 17 4.7 36.4 1.6 1 0 0 1 1 1 0 Vta1 like OTU PF02338.14 EGC35541.1 - 3.8e-13 50.0 0.1 3.8e-13 50.0 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC35541.1 - 0.25 9.5 66.8 0.38 8.9 46.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PAP_RNA-bind PF04926.10 EGC35541.1 - 0.28 10.6 6.2 2.2 7.7 0.1 2.9 1 1 1 2 2 2 0 Poly(A) polymerase predicted RNA binding domain TFIIA PF03153.8 EGC35541.1 - 2.2 8.0 47.8 2.9 7.6 33.1 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SUR7 PF06687.7 EGC35542.1 - 0.0025 17.4 0.9 0.0025 17.4 0.6 2.3 2 1 0 2 2 2 1 SUR7/PalI family DUF2208 PF09973.4 EGC35542.1 - 0.042 13.0 1.0 0.062 12.5 0.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) LANC_like PF05147.8 EGC35543.1 - 0.039 12.5 0.0 0.05 12.1 0.0 1.1 1 0 0 1 1 1 0 Lanthionine synthetase C-like protein DUF4341 PF14241.1 EGC35543.1 - 0.056 13.1 0.0 0.12 12.0 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4341) FKBP_C PF00254.23 EGC35544.1 - 1e-30 105.5 0.1 1.3e-30 105.2 0.1 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase DUF4590 PF15257.1 EGC35544.1 - 0.016 14.9 0.0 0.022 14.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4590) HGTP_anticodon PF03129.15 EGC35544.1 - 0.03 14.2 0.0 0.039 13.8 0.0 1.2 1 0 0 1 1 1 0 Anticodon binding domain Exo_endo_phos PF03372.18 EGC35545.1 - 1.2e-18 67.9 0.5 1.7e-18 67.5 0.4 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family Head_binding PF09008.5 EGC35545.1 - 0.027 14.5 0.3 0.085 12.8 0.2 1.8 1 0 0 1 1 1 0 Head binding LIM PF00412.17 EGC35546.1 - 5.2e-37 125.7 55.7 1.5e-12 47.3 5.0 5.3 5 0 0 5 5 5 4 LIM domain Sgf11 PF08209.6 EGC35546.1 - 7.8 5.9 30.2 1.1 8.6 0.3 6.9 6 0 0 6 6 6 0 Sgf11 (transcriptional regulation protein) AMP-binding PF00501.23 EGC35547.1 - 1e-99 333.7 0.0 1.3e-99 333.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme EcKinase PF02958.15 EGC35548.1 - 4.8e-16 58.7 1.7 1.2e-11 44.2 0.0 2.2 2 0 0 2 2 2 2 Ecdysteroid kinase APH PF01636.18 EGC35548.1 - 3e-05 23.8 0.0 4.2e-05 23.3 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family SNF2_N PF00176.18 EGC35551.1 - 1.8e-77 260.0 0.1 1.8e-77 260.0 0.1 3.1 3 0 0 3 3 3 1 SNF2 family N-terminal domain Bromodomain PF00439.20 EGC35551.1 - 1.1e-19 70.1 0.7 1.1e-19 70.1 0.5 3.1 3 0 0 3 3 3 1 Bromodomain Helicase_C PF00271.26 EGC35551.1 - 3.9e-15 55.4 0.1 3.8e-14 52.3 0.0 2.8 3 0 0 3 3 3 1 Helicase conserved C-terminal domain HSA PF07529.8 EGC35551.1 - 3.6e-14 52.2 12.3 1.9e-13 49.9 8.5 2.4 1 0 0 1 1 1 1 HSA DEAD PF00270.24 EGC35551.1 - 2.1e-08 33.8 0.1 7.9e-08 31.9 0.0 2.0 2 0 0 2 2 2 1 DEAD/DEAH box helicase BAF1_ABF1 PF04684.8 EGC35552.1 - 0.025 13.4 3.2 0.027 13.3 2.2 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF2362 PF10154.4 EGC35552.1 - 0.054 12.1 5.7 0.063 11.9 3.9 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2362) C4 PF01413.14 EGC35552.1 - 0.056 13.3 1.6 0.069 13.0 1.1 1.1 1 0 0 1 1 1 0 C-terminal tandem repeated domain in type 4 procollagen Ribonuc_red_lgC PF02867.10 EGC35552.1 - 0.087 11.3 5.0 0.09 11.3 3.4 1.0 1 0 0 1 1 1 0 Ribonucleotide reductase, barrel domain SapB_2 PF03489.12 EGC35553.1 - 0.00074 19.4 0.1 0.0014 18.6 0.1 1.5 1 0 0 1 1 1 1 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC35553.1 - 0.011 15.5 1.3 0.04 13.7 0.2 2.4 2 1 0 2 2 2 0 Saposin-like type B, region 1 Peptidase_S8 PF00082.17 EGC35554.1 - 1.9e-47 161.7 0.8 1.9e-47 161.7 0.5 1.7 2 0 0 2 2 2 1 Subtilase family ABC2_membrane_3 PF12698.2 EGC35554.1 - 2.8 6.8 17.8 5.5 5.9 12.3 1.4 1 0 0 1 1 1 0 ABC-2 family transporter protein Mito_carr PF00153.22 EGC35555.1 - 1.8e-10 40.3 1.4 0.00049 19.7 0.1 3.7 2 1 1 3 3 3 3 Mitochondrial carrier protein DnaJ PF00226.26 EGC35555.1 - 5.3e-06 26.0 2.7 1.3e-05 24.7 1.9 1.8 1 0 0 1 1 1 1 DnaJ domain DUF438 PF04282.8 EGC35555.1 - 0.042 13.6 1.1 0.17 11.6 0.1 2.3 2 0 0 2 2 2 0 Family of unknown function (DUF438) Phage_Gp23 PF10669.4 EGC35555.1 - 0.054 13.5 3.4 0.11 12.5 2.4 1.5 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) DnaJ PF00226.26 EGC35556.1 - 3.1e-07 30.0 4.2 5.7e-07 29.1 2.9 1.5 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 EGC35556.1 - 1.8e-05 24.3 0.0 0.03 14.0 0.0 2.7 2 0 0 2 2 2 2 Mitochondrial carrier protein FNIP PF05725.7 EGC35557.1 - 1.4e-18 66.5 10.1 4.7e-11 42.4 2.1 2.0 2 0 0 2 2 2 2 FNIP Repeat Ipi1_N PF12333.3 EGC35558.1 - 2.4e-16 59.5 5.3 7e-16 58.0 0.1 3.3 3 0 0 3 3 3 2 Rix1 complex component involved in 60S ribosome maturation Tox-URI2 PF15653.1 EGC35559.1 - 0.031 14.4 4.7 0.086 13.0 3.3 1.8 1 0 0 1 1 1 0 URI fold toxin 2 DUF1943 PF09172.6 EGC35560.1 - 0.019 13.8 0.7 2 7.1 0.3 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1943) DUF3206 PF11472.3 EGC35560.1 - 0.45 10.3 3.1 3.3 7.4 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3206) FA_desaturase PF00487.19 EGC35561.1 - 3.7e-32 111.7 8.3 3.7e-32 111.7 5.8 1.9 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGC35561.1 - 9.9e-24 82.9 0.0 1.9e-23 82.0 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Jiv90 PF14901.1 EGC35561.1 - 0.0088 16.0 0.1 0.02 14.8 0.0 1.5 1 0 0 1 1 1 1 Cleavage inducing molecular chaperone tRNA-synt_1b PF00579.20 EGC35562.1 - 2.6e-24 85.8 0.0 6.3e-24 84.5 0.0 1.7 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) HsdM_N PF12161.3 EGC35562.1 - 0.011 16.1 0.7 5 7.5 0.1 2.4 2 0 0 2 2 2 0 HsdM N-terminal domain DUF4455 PF14643.1 EGC35562.1 - 0.095 11.3 0.5 0.22 10.1 0.3 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4455) MIF4G_like_2 PF09090.6 EGC35563.1 - 3.1e-50 170.7 16.0 3.5e-50 170.6 9.2 2.3 2 0 0 2 2 2 1 MIF4G like MIF4G_like PF09088.6 EGC35563.1 - 5e-32 110.8 8.1 1.3e-29 103.0 3.7 3.7 1 1 1 2 2 2 2 MIF4G like CRAL_TRIO PF00650.15 EGC35564.1 - 6.6e-28 97.1 0.2 1.2e-27 96.3 0.1 1.4 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGC35564.1 - 3.6e-07 30.1 1.7 3.6e-07 30.1 1.2 3.0 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain CRAL_TRIO_2 PF13716.1 EGC35564.1 - 0.02 14.7 2.3 0.03 14.2 0.1 2.4 3 1 0 3 3 3 0 Divergent CRAL/TRIO domain DUF3439 PF11921.3 EGC35564.1 - 0.025 14.3 4.4 0.052 13.2 3.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Auxin_repressed PF05564.7 EGC35564.1 - 0.033 14.8 3.7 1.4 9.5 0.6 2.4 2 0 0 2 2 2 0 Dormancy/auxin associated protein Mucin PF01456.12 EGC35564.1 - 0.24 11.1 16.4 1 9.1 10.3 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein Arrestin_C PF02752.17 EGC35565.1 - 4.5e-18 65.6 3.5 7.9e-15 55.1 1.1 2.4 2 0 0 2 2 2 2 Arrestin (or S-antigen), C-terminal domain C2 PF00168.25 EGC35565.1 - 1.7e-12 47.0 0.0 3.8e-12 45.8 0.0 1.7 1 0 0 1 1 1 1 C2 domain Arrestin_N PF00339.24 EGC35565.1 - 3.5e-06 26.9 0.3 0.00038 20.3 0.0 3.0 2 2 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain SAM_1 PF00536.25 EGC35565.1 - 3e-05 24.1 0.0 7.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) PRA1 PF03208.14 EGC35568.1 - 2.2e-28 98.5 2.6 4.1e-28 97.6 1.8 1.4 1 0 0 1 1 1 1 PRA1 family protein DUF1242 PF06842.7 EGC35568.1 - 0.1 12.0 0.2 0.1 12.0 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1242) TMCO5 PF14992.1 EGC35568.1 - 4.2 6.4 4.7 7.9 5.5 3.2 1.4 1 1 0 1 1 1 0 TMCO5 family p450 PF00067.17 EGC35569.1 - 1.4e-87 294.1 0.3 1.7e-87 293.8 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 SecY PF00344.15 EGC35570.1 - 4.5e-98 328.3 14.7 5.7e-98 328.0 10.2 1.1 1 0 0 1 1 1 1 SecY translocase Plug_translocon PF10559.4 EGC35570.1 - 2.7e-18 65.1 0.1 1.4e-17 62.9 0.1 2.3 1 0 0 1 1 1 1 Plug domain of Sec61p Steroid_dh PF02544.11 EGC35570.1 - 0.0064 16.2 0.3 0.018 14.7 0.2 1.8 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase CBS PF00571.23 EGC35571.1 - 1e-21 76.4 1.3 3.2e-07 30.0 0.0 4.2 4 0 0 4 4 4 4 CBS domain CIMR PF00878.13 EGC35572.1 - 2.3e-07 30.7 1.0 9.8e-06 25.3 0.4 2.4 2 0 0 2 2 2 2 Cation-independent mannose-6-phosphate receptor repeat CDC45 PF02724.9 EGC35572.1 - 3 5.7 25.9 3.9 5.3 18.0 1.1 1 0 0 1 1 1 0 CDC45-like protein Methyltransf_12 PF08242.7 EGC35573.1 - 1.4 9.4 3.8 1.2 9.6 0.7 2.1 2 0 0 2 2 2 0 Methyltransferase domain CBM49 PF09478.5 EGC35575.1 - 3.4e-20 71.9 4.2 1.5e-19 69.8 2.9 2.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 KNTase_C PF07827.6 EGC35575.1 - 0.041 13.6 0.0 0.19 11.5 0.0 2.0 2 0 0 2 2 2 0 KNTase C-terminal domain zf-SNAP50_C PF12251.3 EGC35576.1 - 0.016 14.6 0.4 0.016 14.5 0.3 1.1 1 0 0 1 1 1 0 snRNA-activating protein of 50kDa MW C terminal DUF866 PF05907.8 EGC35576.1 - 0.025 14.0 0.1 0.03 13.8 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF866) MFS_2 PF13347.1 EGC35576.1 - 0.67 8.2 2.7 0.87 7.9 1.9 1.1 1 0 0 1 1 1 0 MFS/sugar transport protein Ank_3 PF13606.1 EGC35578.1 - 0.093 13.0 0.9 27 5.4 0.1 2.8 2 0 0 2 2 2 0 Ankyrin repeat Pex14_N PF04695.8 EGC35578.1 - 1.1 9.3 7.4 0.31 11.0 1.0 2.2 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2457 PF10446.4 EGC35578.1 - 5.8 5.5 9.3 7.8 5.1 6.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Ribosomal_S28e PF01200.13 EGC35579.1 - 5.7e-32 109.2 3.2 6.2e-32 109.1 2.2 1.0 1 0 0 1 1 1 1 Ribosomal protein S28e Endonuc-BsobI PF09194.5 EGC35579.1 - 0.11 11.4 0.0 0.12 11.2 0.0 1.1 1 0 0 1 1 1 0 Restriction endonuclease BsobI Nfu_N PF08712.6 EGC35580.1 - 1.8e-31 107.5 0.0 4.1e-31 106.4 0.0 1.6 2 0 0 2 2 2 1 Scaffold protein Nfu/NifU N terminal NifU PF01106.12 EGC35580.1 - 1.8e-21 75.6 0.1 2.7e-21 75.0 0.1 1.3 1 0 0 1 1 1 1 NifU-like domain 2OG-FeII_Oxy_2 PF13532.1 EGC35581.1 - 7e-43 146.7 0.0 1.6e-42 145.5 0.0 1.6 1 1 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGC35581.1 - 0.0011 19.2 0.0 0.0021 18.2 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily Macoilin PF09726.4 EGC35583.1 - 2 6.6 16.2 2.8 6.1 11.2 1.1 1 0 0 1 1 1 0 Transmembrane protein Nup84_Nup100 PF04121.8 EGC35584.1 - 7.9e-98 327.9 29.8 8.8e-97 324.4 20.7 2.1 1 1 0 1 1 1 1 Nuclear pore protein 84 / 107 CBM49 PF09478.5 EGC35585.1 - 1e-19 70.3 3.8 4.4e-19 68.3 2.6 2.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.5 EGC35586.1 - 4e-15 55.6 5.2 2.8e-14 52.9 3.3 2.6 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 CBM49 PF09478.5 EGC35587.1 - 1.8e-19 69.5 5.3 1.8e-19 69.5 3.7 3.1 4 0 0 4 4 4 1 Carbohydrate binding domain CBM49 Ribosomal_L27 PF01016.14 EGC35589.1 - 2.4e-36 123.3 1.0 2.8e-36 123.1 0.7 1.1 1 0 0 1 1 1 1 Ribosomal L27 protein ECR1_N PF14382.1 EGC35589.1 - 0.0072 15.5 0.1 0.017 14.3 0.1 1.7 1 1 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region Usp PF00582.21 EGC35590.1 - 3e-07 30.7 0.0 4.2e-07 30.2 0.0 1.2 1 0 0 1 1 1 1 Universal stress protein family Pilin PF00114.14 EGC35590.1 - 0.62 10.7 4.6 1.1 10.0 3.2 1.4 1 0 0 1 1 1 0 Pilin (bacterial filament) Glucosamine_iso PF01182.15 EGC35591.1 - 3.1e-25 89.0 0.0 4.3e-25 88.6 0.0 1.1 1 0 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Drf_GBD PF06371.8 EGC35592.1 - 0.0078 15.5 1.4 0.0082 15.5 1.0 1.0 1 0 0 1 1 1 1 Diaphanous GTPase-binding Domain Pilin_PilX PF11530.3 EGC35592.1 - 0.029 14.0 0.7 0.03 13.9 0.5 1.0 1 0 0 1 1 1 0 Minor type IV pilin, PilX TRF PF08558.5 EGC35592.1 - 0.06 12.6 0.1 0.06 12.6 0.1 1.0 1 0 0 1 1 1 0 Telomere repeat binding factor (TRF) Mito_carr PF00153.22 EGC35593.1 - 1.9e-79 261.5 1.9 2.3e-25 88.1 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_1 PF00036.27 EGC35593.1 - 1.2e-10 39.8 2.8 7.3e-06 24.9 0.3 2.7 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGC35593.1 - 1.6e-09 37.7 2.1 4.9e-09 36.2 1.5 1.9 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_6 PF13405.1 EGC35593.1 - 8.2e-09 34.6 0.7 3e-05 23.5 0.3 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGC35593.1 - 1.1e-06 27.6 1.9 3.3e-05 23.0 0.8 2.6 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGC35593.1 - 0.00021 20.8 3.0 0.14 11.7 0.2 2.6 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC35593.1 - 0.0071 16.3 4.1 0.012 15.6 2.8 1.3 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region CytB6-F_Fe-S PF08802.5 EGC35593.1 - 4.9 7.2 8.9 3.1 7.8 0.4 3.2 3 0 0 3 3 3 0 Cytochrome B6-F complex Fe-S subunit YecM PF06185.7 EGC35594.1 - 1.3e-15 57.0 0.2 1.6e-15 56.8 0.1 1.1 1 0 0 1 1 1 1 YecM protein tRNA-synt_1g PF09334.6 EGC35595.1 - 9e-125 416.3 0.0 1.5e-124 415.6 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (M) tRNA-synt_1 PF00133.17 EGC35595.1 - 4e-26 91.1 3.8 6.9e-14 50.7 0.6 3.9 1 1 2 3 3 3 2 tRNA synthetases class I (I, L, M and V) tRNA-synt_1e PF01406.14 EGC35595.1 - 2.6e-08 33.3 0.0 0.0022 17.1 0.0 2.2 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain Anticodon_1 PF08264.8 EGC35595.1 - 0.0012 18.6 0.0 0.0059 16.3 0.0 2.2 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA tRNA-synt_1d PF00750.14 EGC35595.1 - 0.0095 14.7 0.0 0.018 13.8 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EGC35595.1 - 0.02 13.5 0.0 0.24 10.0 0.0 2.0 2 0 0 2 2 2 0 tRNA synthetases class I (K) DUF2296 PF10058.4 EGC35596.1 - 3.3e-11 42.7 0.9 6.2e-11 41.8 0.6 1.5 1 0 0 1 1 1 1 Predicted integral membrane metal-binding protein (DUF2296) Suf PF05843.9 EGC35596.1 - 0.0015 18.3 17.2 0.0024 17.6 11.9 1.4 1 0 0 1 1 1 1 Suppressor of forked protein (Suf) PAT1 PF09770.4 EGC35596.1 - 0.0025 16.1 40.7 0.0031 15.8 28.2 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 DDHD PF02862.12 EGC35596.1 - 0.0095 15.7 10.7 0.014 15.1 7.4 1.3 1 0 0 1 1 1 1 DDHD domain Zip PF02535.17 EGC35596.1 - 0.0098 14.9 0.0 0.014 14.3 0.0 1.3 1 0 0 1 1 1 1 ZIP Zinc transporter ORC6 PF05460.8 EGC35596.1 - 0.012 14.7 11.2 0.017 14.2 7.7 1.2 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) DUF605 PF04652.11 EGC35596.1 - 0.019 14.3 25.2 0.025 14.0 17.5 1.1 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 EGC35596.1 - 0.15 11.2 17.3 0.23 10.7 12.0 1.2 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Cation_ATPase_C PF00689.16 EGC35596.1 - 0.3 10.5 3.6 0.51 9.8 2.5 1.3 1 0 0 1 1 1 0 Cation transporting ATPase, C-terminus TFIIA PF03153.8 EGC35596.1 - 0.35 10.7 30.1 0.46 10.3 20.9 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SprA-related PF12118.3 EGC35596.1 - 0.4 9.9 36.6 0.54 9.5 25.3 1.1 1 0 0 1 1 1 0 SprA-related family GAGA_bind PF06217.7 EGC35596.1 - 0.43 10.5 18.0 0.65 9.9 12.5 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EGC35596.1 - 0.68 9.7 16.2 1.1 9.0 11.2 1.3 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 Aconitase PF00330.15 EGC35596.1 - 2.4 6.5 5.8 3.5 5.9 4.0 1.3 1 0 0 1 1 1 0 Aconitase family (aconitate hydratase) DUF2201_N PF13203.1 EGC35596.1 - 3.1 6.8 16.1 4.2 6.4 11.1 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain DUF4484 PF14831.1 EGC35596.1 - 4.1 7.4 8.4 17 5.5 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4484) DUF4175 PF13779.1 EGC35596.1 - 4.6 4.8 38.3 7.4 4.1 26.5 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3373 PF11853.3 EGC35596.1 - 6.6 5.1 10.8 10 4.4 7.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) PEX11 PF05648.9 EGC35596.1 - 6.9 5.8 7.0 4.9 6.3 3.3 1.8 2 0 0 2 2 2 0 Peroxisomal biogenesis factor 11 (PEX11) UPF0066 PF01980.11 EGC35597.1 - 5.6e-40 136.0 0.3 1.1e-37 128.6 0.2 2.6 1 1 0 1 1 1 1 Uncharacterised protein family UPF0066 G-7-MTase PF12803.2 EGC35597.1 - 0.0074 15.4 2.6 0.017 14.2 1.8 1.6 1 0 0 1 1 1 1 mRNA (guanine-7-)methyltransferase (G-7-MTase) DUF4657 PF15552.1 EGC35597.1 - 0.3 10.3 4.9 0.71 9.1 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4657) Mucin PF01456.12 EGC35597.1 - 0.32 10.7 19.1 0.051 13.3 10.5 1.6 2 0 0 2 2 2 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGC35597.1 - 0.38 10.4 9.3 0.022 14.5 2.7 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) SSP160 PF06933.6 EGC35597.1 - 0.77 7.6 11.6 1.1 7.1 8.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Glyco_hydro_61 PF03443.9 EGC35598.1 - 0.015 15.0 0.8 0.017 14.9 0.6 1.0 1 0 0 1 1 1 0 Glycosyl hydrolase family 61 DJ-1_PfpI PF01965.19 EGC35599.1 - 2.5e-24 85.4 0.0 3.3e-24 85.0 0.0 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGC35599.1 - 5.4e-21 74.5 0.0 6.3e-21 74.3 0.0 1.1 1 0 0 1 1 1 1 Putative amidotransferase GATase_5 PF13507.1 EGC35599.1 - 0.0061 15.4 0.0 0.014 14.3 0.0 1.5 1 1 0 1 1 1 1 CobB/CobQ-like glutamine amidotransferase domain GATase_3 PF07685.9 EGC35599.1 - 0.012 15.2 0.0 0.016 14.8 0.0 1.3 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain GATase PF00117.23 EGC35599.1 - 0.078 12.4 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Actin PF00022.14 EGC35600.1 - 1.8e-101 339.4 0.1 2e-101 339.2 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC35600.1 - 0.0011 17.5 0.0 0.31 9.5 0.0 2.5 2 1 0 2 2 2 2 MreB/Mbl protein DHFR_1 PF00186.14 EGC35600.1 - 0.013 15.0 0.0 0.13 11.8 0.0 2.4 3 0 0 3 3 3 0 Dihydrofolate reductase TLD PF07534.11 EGC35601.1 - 3.9e-36 124.0 2.0 3.9e-36 124.0 1.4 3.3 5 1 0 5 5 5 1 TLD hSac2 PF12456.3 EGC35601.1 - 3.4e-22 78.0 0.2 1.2e-21 76.2 0.1 2.0 1 0 0 1 1 1 1 Inositol phosphatase CBFD_NFYB_HMF PF00808.18 EGC35602.1 - 2.3e-18 66.0 0.6 3.6e-18 65.3 0.4 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC35602.1 - 0.00032 20.7 0.0 0.00047 20.2 0.0 1.3 1 1 0 1 1 1 1 Core histone H2A/H2B/H3/H4 TAF4 PF05236.9 EGC35602.1 - 0.0097 15.2 0.1 0.011 15.0 0.0 1.1 1 0 0 1 1 1 1 Transcription initiation factor TFIID component TAF4 family TFIID_20kDa PF03847.8 EGC35602.1 - 0.038 14.2 0.2 0.076 13.3 0.1 1.6 1 1 0 1 1 1 0 Transcription initiation factor TFIID subunit A Pox_RNA_Pol_19 PF05320.7 EGC35602.1 - 0.048 13.4 0.1 0.065 12.9 0.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PerB PF06590.6 EGC35602.1 - 0.068 13.4 0.1 0.083 13.1 0.0 1.2 1 0 0 1 1 1 0 PerB protein TFIID-18kDa PF02269.11 EGC35602.1 - 0.086 12.6 0.2 0.25 11.1 0.1 1.7 1 1 1 2 2 2 0 Transcription initiation factor IID, 18kD subunit DUF2763 PF10961.3 EGC35604.1 - 7.5 7.0 5.6 31 5.0 1.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2763) SPRY PF00622.23 EGC35605.1 - 0.00023 21.2 1.0 0.00067 19.7 0.4 1.9 1 1 1 2 2 2 1 SPRY domain p450 PF00067.17 EGC35606.1 - 1.5e-85 287.4 3.6 1.7e-85 287.2 2.5 1.0 1 0 0 1 1 1 1 Cytochrome P450 CLN5 PF15014.1 EGC35607.1 - 0.12 11.6 0.0 0.12 11.6 0.0 1.0 1 0 0 1 1 1 0 Ceroid-lipofuscinosis neuronal protein 5 FNIP PF05725.7 EGC35608.1 - 8.2e-106 345.7 34.6 1.1e-17 63.7 0.2 8.0 5 2 4 9 9 9 9 FNIP Repeat Phage_min_tail PF05939.8 EGC35608.1 - 0.0016 18.3 0.0 33 4.4 0.0 5.6 3 2 4 7 7 7 0 Phage minor tail protein LRR_6 PF13516.1 EGC35608.1 - 0.031 14.3 22.9 1.3e+02 3.1 0.0 10.8 13 0 0 13 13 13 0 Leucine Rich repeat SSURE PF11966.3 EGC35608.1 - 0.1 12.1 2.6 23 4.6 0.0 4.6 3 2 2 6 6 6 0 Fibronectin-binding repeat DUF1769 PF08588.5 EGC35608.1 - 0.71 9.8 24.2 14 5.6 0.3 7.9 2 2 9 11 11 11 0 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC35609.1 - 3.4e-168 545.4 64.3 1.4e-16 60.1 0.1 13.1 9 2 5 14 14 14 14 FNIP Repeat Bclx_interact PF08945.5 EGC35609.1 - 0.9 9.1 4.2 1.9e+02 1.6 0.0 5.1 5 0 0 5 5 5 0 Bcl-x interacting, BH3 domain B-block_TFIIIC PF04182.7 EGC35611.1 - 6.2e-17 61.2 4.4 4e-14 52.2 0.1 3.8 3 0 0 3 3 3 2 B-block binding subunit of TFIIIC DinI PF06183.8 EGC35613.1 - 0.013 15.4 0.6 0.055 13.4 0.1 2.3 2 0 0 2 2 2 0 DinI-like family RNA_pol_3_Rpc31 PF11705.3 EGC35613.1 - 0.064 13.1 28.9 0.12 12.2 19.1 2.2 1 1 0 1 1 1 0 DNA-directed RNA polymerase III subunit Rpc31 CDC45 PF02724.9 EGC35613.1 - 0.46 8.4 6.9 0.97 7.3 4.8 1.5 1 0 0 1 1 1 0 CDC45-like protein Mito_carr PF00153.22 EGC35614.1 - 2.3e-71 235.5 1.8 1.8e-22 78.8 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF2357 PF09823.4 EGC35614.1 - 0.069 12.2 0.0 0.13 11.3 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF2357) DUF2132 PF09905.4 EGC35614.1 - 0.1 12.5 0.0 0.25 11.3 0.0 1.6 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2132) LRR_4 PF12799.2 EGC35615.1 - 1.9e-08 33.7 9.9 7.2e-08 31.8 2.1 6.5 2 2 3 6 6 6 3 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC35615.1 - 1.9e-05 24.2 8.6 0.0004 20.1 0.5 8.8 10 2 0 10 10 10 5 Leucine Rich repeat LRR_8 PF13855.1 EGC35615.1 - 0.0025 17.5 6.3 0.0025 17.5 4.4 5.6 3 1 2 6 6 6 2 Leucine rich repeat LRR_7 PF13504.1 EGC35615.1 - 0.0032 17.3 21.0 0.64 10.4 0.1 7.0 7 1 0 7 7 7 3 Leucine rich repeat F-box-like PF12937.2 EGC35615.1 - 0.037 13.7 0.6 0.092 12.4 0.4 1.6 1 0 0 1 1 1 0 F-box-like LRR_1 PF00560.28 EGC35615.1 - 0.047 13.7 0.2 0.047 13.7 0.2 8.6 8 2 1 10 10 10 0 Leucine Rich Repeat DAO PF01266.19 EGC35616.1 - 2.3e-56 191.2 0.0 2.6e-56 191.0 0.0 1.0 1 0 0 1 1 1 1 FAD dependent oxidoreductase GIDA PF01134.17 EGC35616.1 - 3.2e-07 29.5 0.0 0.00024 20.1 0.0 2.2 2 0 0 2 2 2 2 Glucose inhibited division protein A Pyr_redox_2 PF07992.9 EGC35616.1 - 5.6e-06 26.3 0.2 0.053 13.4 0.1 2.3 2 0 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGC35616.1 - 1.2e-05 23.9 0.1 0.048 12.1 0.0 2.3 2 0 0 2 2 2 2 HI0933-like protein FAD_binding_2 PF00890.19 EGC35616.1 - 2.2e-05 23.4 0.0 0.0069 15.2 0.0 2.2 2 0 0 2 2 2 2 FAD binding domain NAD_binding_8 PF13450.1 EGC35616.1 - 0.00014 21.8 0.1 0.00033 20.6 0.0 1.7 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGC35616.1 - 0.00026 20.1 0.1 0.00048 19.2 0.0 1.4 1 0 0 1 1 1 1 Thi4 family FAD_oxidored PF12831.2 EGC35616.1 - 0.028 13.4 0.0 0.044 12.8 0.0 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox_3 PF13738.1 EGC35616.1 - 0.03 14.3 0.1 0.89 9.5 0.0 2.2 1 1 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGC35616.1 - 0.12 12.0 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Amino_oxidase PF01593.19 EGC35616.1 - 0.14 11.2 0.0 0.3 10.1 0.0 1.5 2 0 0 2 2 2 0 Flavin containing amine oxidoreductase FAD_binding_3 PF01494.14 EGC35616.1 - 0.15 11.0 0.0 0.29 10.1 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain PEPCK_ATP PF01293.15 EGC35618.1 - 2.4e-40 138.4 4.4 1.5e-23 83.1 0.1 2.1 2 0 0 2 2 2 2 Phosphoenolpyruvate carboxykinase TMEM154 PF15102.1 EGC35619.1 - 0.00015 21.4 0.2 0.00026 20.7 0.1 1.3 1 0 0 1 1 1 1 TMEM154 protein family ETRAMP PF09716.5 EGC35620.1 - 7.6e-05 22.5 11.3 0.00059 19.7 4.2 3.0 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF4448 PF14610.1 EGC35620.1 - 0.0014 18.1 0.0 0.0035 16.8 0.0 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF4448) Sarcoglycan_2 PF05510.8 EGC35620.1 - 0.0021 16.4 0.1 0.0039 15.5 0.1 1.4 1 0 0 1 1 1 1 Sarcoglycan alpha/epsilon DUF1180 PF06679.7 EGC35620.1 - 0.0087 15.9 0.3 0.013 15.3 0.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1180) Pex14_N PF04695.8 EGC35620.1 - 0.018 15.0 3.6 0.018 15.0 2.5 2.1 1 1 1 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF2905 PF11146.3 EGC35620.1 - 0.26 11.2 3.4 2.8 7.9 0.5 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2905) DUF912 PF06024.7 EGC35620.1 - 0.95 9.5 8.2 0.52 10.3 3.6 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) PRCC PF10253.4 EGC35621.1 - 0.00026 21.7 27.0 0.00026 21.7 18.7 3.9 2 1 2 4 4 4 2 Mitotic checkpoint regulator, MAD2B-interacting ATP_bind_1 PF03029.12 EGC35622.1 - 6.7e-88 294.2 0.2 7.6e-88 294.0 0.1 1.0 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein GTP_EFTU PF00009.22 EGC35622.1 - 0.00012 21.6 0.0 0.00074 18.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain CbiA PF01656.18 EGC35622.1 - 0.00097 18.5 0.0 0.0017 17.8 0.0 1.5 1 1 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_30 PF13604.1 EGC35622.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC35622.1 - 0.0011 19.8 0.8 0.0028 18.4 0.1 2.2 2 1 0 2 2 2 1 AAA domain AAA_29 PF13555.1 EGC35622.1 - 0.0041 16.5 0.0 0.007 15.8 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain MobB PF03205.9 EGC35622.1 - 0.008 15.8 0.0 0.31 10.7 0.0 2.3 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B KTI12 PF08433.5 EGC35622.1 - 0.012 14.8 0.0 0.1 11.7 0.0 2.0 2 0 0 2 2 2 0 Chromatin associated protein KTI12 ArgK PF03308.11 EGC35622.1 - 0.037 12.7 0.0 0.23 10.1 0.0 2.0 2 0 0 2 2 2 0 ArgK protein AAA_16 PF13191.1 EGC35622.1 - 0.053 13.5 0.0 0.16 11.9 0.0 1.8 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGC35622.1 - 0.056 13.5 0.0 0.13 12.4 0.0 1.8 1 1 0 1 1 1 0 AAA domain MMR_HSR1 PF01926.18 EGC35622.1 - 0.08 12.9 0.0 0.2 11.5 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC35622.1 - 0.099 12.1 0.0 16 5.0 0.0 2.6 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation RNA_helicase PF00910.17 EGC35622.1 - 0.12 12.6 0.0 0.2 11.8 0.0 1.4 1 0 0 1 1 1 0 RNA helicase SRP54 PF00448.17 EGC35622.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_18 PF13238.1 EGC35622.1 - 0.15 12.3 0.3 0.77 10.0 0.0 2.3 2 2 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC35622.1 - 0.16 11.5 0.0 0.29 10.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain Methyltransf_16 PF10294.4 EGC35623.1 - 2.6e-23 82.3 0.6 3.9e-23 81.7 0.4 1.2 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGC35623.1 - 1.6e-06 27.5 0.0 2.5e-06 26.9 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGC35623.1 - 9.6e-05 22.9 0.0 0.00014 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC35623.1 - 0.0037 16.9 0.0 0.0059 16.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC35623.1 - 0.0059 16.2 0.6 0.015 14.9 0.3 1.8 1 1 1 2 2 2 1 Methyltransferase domain TehB PF03848.9 EGC35623.1 - 0.013 14.7 0.2 0.021 14.0 0.1 1.4 1 0 0 1 1 1 0 Tellurite resistance protein TehB RrnaAD PF00398.15 EGC35623.1 - 0.021 13.8 0.0 0.031 13.3 0.0 1.2 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase PrmA PF06325.8 EGC35623.1 - 0.04 13.0 0.0 0.06 12.4 0.0 1.2 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC35623.1 - 0.11 12.5 0.0 0.14 12.1 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Pheromone PF08015.6 EGC35625.1 - 0.042 14.6 0.2 0.047 14.5 0.1 1.1 1 0 0 1 1 1 0 Fungal mating-type pheromone CBS PF00571.23 EGC35626.1 - 1.3e-24 85.6 2.3 3.7e-13 49.0 0.1 2.2 2 0 0 2 2 2 2 CBS domain Prenyltrans PF00432.16 EGC35627.1 - 3.1e-67 221.7 1.8 3.5e-13 48.8 0.2 5.9 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGC35627.1 - 4e-39 133.5 0.0 2.3e-19 69.8 0.0 3.6 1 1 3 4 4 4 4 Prenyltransferase-like Prenyltrans_1 PF13243.1 EGC35627.1 - 3.3e-15 56.0 0.0 1.2e-07 31.6 0.0 3.3 2 1 1 3 3 3 2 Prenyltransferase-like A2M_comp PF07678.9 EGC35627.1 - 0.00035 19.8 0.0 1.7 7.8 0.0 3.8 2 1 2 4 4 4 1 A-macroglobulin complement component Cellulase PF00150.13 EGC35631.1 - 4.2e-39 134.4 0.5 7e-39 133.7 0.3 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Potyvirid-P3 PF13608.1 EGC35632.1 - 3.4 6.6 11.4 5.1 6.1 7.9 1.2 1 0 0 1 1 1 0 Protein P3 of Potyviral polyprotein MYEOV2 PF15004.1 EGC35633.1 - 0.04 14.4 7.5 0.04 14.4 5.2 2.1 1 1 1 2 2 2 0 Myeloma-overexpressed-like zf-RING_2 PF13639.1 EGC35634.1 - 6.4e-11 41.9 8.0 1e-10 41.2 5.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC35634.1 - 7.2e-08 31.9 4.4 1.1e-07 31.4 3.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC35634.1 - 8.7e-07 28.9 8.5 3.3e-06 27.0 5.9 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC35634.1 - 1.3e-06 27.9 6.3 1.9e-06 27.3 4.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC35634.1 - 3.1e-06 27.0 7.7 5e-06 26.4 5.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC35634.1 - 4.1e-06 26.4 4.0 7.4e-06 25.6 2.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC35634.1 - 1.3e-05 24.8 3.4 1.4e-05 24.7 1.6 1.7 1 1 0 1 1 1 1 RING-type zinc-finger Prok-RING_4 PF14447.1 EGC35634.1 - 0.0012 18.3 1.5 0.0021 17.5 1.1 1.4 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC35634.1 - 0.0051 16.6 5.4 0.025 14.4 3.8 2.0 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC35634.1 - 0.026 14.4 5.4 0.045 13.6 3.7 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EGC35634.1 - 0.13 12.3 5.0 0.27 11.3 3.5 1.5 1 1 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGC35634.1 - 0.39 10.3 4.7 2 8.0 3.3 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain DUF2968 PF11180.3 EGC35635.1 - 0.17 11.2 5.7 0.34 10.2 3.3 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) PAS_10 PF13596.1 EGC35635.1 - 0.24 11.6 0.2 0.24 11.6 0.1 2.8 1 1 1 3 3 3 0 PAS domain DUF4509 PF14970.1 EGC35635.1 - 0.71 9.5 6.0 1.4 8.5 4.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) IQ-like PF15157.1 EGC35635.1 - 1.1 9.4 13.4 4.4 7.5 0.2 2.4 2 1 0 2 2 2 0 IQ-like Herpes_UL25 PF01499.11 EGC35635.1 - 1.9 6.7 7.5 2.5 6.3 5.2 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Tox-ODYAM1 PF15642.1 EGC35635.1 - 2.2 6.8 18.7 0.27 9.8 9.9 1.7 1 1 1 2 2 2 0 Toxin in Odyssella and Amoebophilus OTU PF02338.14 EGC35636.1 - 4e-13 50.0 1.8 6.3e-13 49.3 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Tetraspannin PF00335.15 EGC35636.1 - 7.9e-05 22.0 0.6 9e-05 21.8 0.4 1.2 1 0 0 1 1 1 1 Tetraspanin family BRF1 PF07741.8 EGC35636.1 - 0.0013 18.8 3.1 0.0024 18.0 2.2 1.4 1 0 0 1 1 1 1 Brf1-like TBP-binding domain PAT1 PF09770.4 EGC35636.1 - 0.0051 15.1 21.5 0.0062 14.8 14.9 1.2 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 Ctr PF04145.10 EGC35636.1 - 0.0061 16.6 2.2 0.02 14.9 1.5 1.9 1 1 0 1 1 1 1 Ctr copper transporter family Shisa PF13908.1 EGC35636.1 - 0.0088 16.2 5.0 0.015 15.4 3.5 1.3 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Zip PF02535.17 EGC35636.1 - 0.055 12.4 0.8 0.076 12.0 0.6 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EGC35636.1 - 0.13 12.0 0.7 0.16 11.8 0.5 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Ndc1_Nup PF09531.5 EGC35636.1 - 0.3 9.4 4.3 0.36 9.1 3.0 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Lin-8 PF03353.10 EGC35636.1 - 1.5 8.0 13.7 2.3 7.4 9.5 1.3 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist DUF4175 PF13779.1 EGC35636.1 - 8.3 3.9 26.6 11 3.5 18.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AKAP7_NLS PF10469.4 EGC35638.1 - 2.8e-18 66.4 5.9 3.1e-18 66.2 4.1 1.0 1 0 0 1 1 1 1 AKAP7 2'5' RNA ligase-like domain 2_5_RNA_ligase2 PF13563.1 EGC35638.1 - 0.00026 20.7 0.0 0.00052 19.7 0.0 1.4 1 1 0 1 1 1 1 2'-5' RNA ligase superfamily HVSL PF09749.4 EGC35638.1 - 0.0057 15.6 1.9 0.007 15.4 0.2 1.7 2 0 0 2 2 2 1 Uncharacterised conserved protein TFIIS_M PF07500.9 EGC35638.1 - 1.3 9.0 5.7 3.3 7.8 3.4 2.1 1 1 1 2 2 2 0 Transcription factor S-II (TFIIS), central domain TraD_N PF12615.3 EGC35639.1 - 0.2 12.0 5.0 3.8 7.9 0.2 2.2 2 0 0 2 2 2 0 F sex factor protein N terminal FYVE PF01363.16 EGC35640.1 - 5.6e-18 64.6 10.3 1e-17 63.7 7.2 1.5 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_N PF00339.24 EGC35640.1 - 1e-14 54.5 0.1 8.5e-13 48.3 0.0 3.1 3 0 0 3 3 3 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGC35640.1 - 2.8e-14 53.3 0.0 1.6e-12 47.7 0.0 2.5 2 0 0 2 2 2 1 Arrestin (or S-antigen), C-terminal domain FYVE_2 PF02318.11 EGC35640.1 - 0.012 15.5 5.4 0.029 14.2 3.7 1.6 1 0 0 1 1 1 0 FYVE-type zinc finger DSPc PF00782.15 EGC35641.1 - 7.1e-08 32.1 0.0 5.2e-07 29.3 0.0 2.1 1 1 1 2 2 2 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC35641.1 - 1.2e-06 28.0 0.0 1.7e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC35641.1 - 0.00041 20.6 0.0 0.00069 19.8 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase2 PF03162.8 EGC35641.1 - 0.0014 17.9 0.0 0.0022 17.4 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family PTPlike_phytase PF14566.1 EGC35641.1 - 0.018 15.0 0.0 0.043 13.8 0.0 1.6 1 0 0 1 1 1 0 Inositol hexakisphosphate Lactamase_B_2 PF12706.2 EGC35641.1 - 0.023 14.2 0.0 0.03 13.8 0.0 1.3 1 1 0 1 1 1 0 Beta-lactamase superfamily domain Glyco_hydro_47 PF01532.15 EGC35642.1 - 2.5e-138 461.5 0.1 2.9e-138 461.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 GlcNAc_2-epim PF07221.6 EGC35642.1 - 0.015 14.3 0.0 5 6.0 0.0 3.2 3 1 1 4 4 4 0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) MDH PF02315.11 EGC35642.1 - 0.4 10.6 3.3 0.76 9.7 2.3 1.4 1 0 0 1 1 1 0 Methanol dehydrogenase beta subunit Sod_Cu PF00080.15 EGC35644.1 - 2.8e-32 111.8 0.5 2.1e-23 83.0 1.5 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) Myb_DNA-binding PF00249.26 EGC35645.1 - 0.0071 16.3 0.0 0.025 14.6 0.0 2.0 1 0 0 1 1 1 1 Myb-like DNA-binding domain I_LWEQ PF01608.12 EGC35646.1 - 0.012 15.5 0.2 0.021 14.7 0.1 1.4 1 1 0 1 1 1 0 I/LWEQ domain ABC2_membrane_4 PF12730.2 EGC35647.1 - 0.0026 16.9 7.7 0.0035 16.5 5.4 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein PRA1 PF03208.14 EGC35647.1 - 0.011 15.1 4.5 0.039 13.3 3.2 1.7 1 1 0 1 1 1 0 PRA1 family protein Methyltransf_12 PF08242.7 EGC35647.1 - 0.074 13.5 0.3 0.11 12.9 0.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain DUF2418 PF10332.4 EGC35647.1 - 7.2 6.9 10.5 38 4.6 7.3 2.1 1 1 0 1 1 1 0 Protein of unknown function (DUF2418) RUN PF02759.14 EGC35648.1 - 2.1e-06 27.5 0.1 6e-06 26.0 0.1 1.9 1 0 0 1 1 1 1 RUN domain FAD_binding_3 PF01494.14 EGC35649.1 - 9.2e-20 70.9 0.0 2.8e-19 69.3 0.0 1.8 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGC35649.1 - 0.00022 21.1 0.0 0.0005 20.0 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EGC35649.1 - 0.00033 19.5 0.0 0.004 16.0 0.0 2.1 2 0 0 2 2 2 1 Squalene epoxidase DAO PF01266.19 EGC35649.1 - 0.004 16.1 0.0 0.078 11.8 0.0 2.0 2 0 0 2 2 2 1 FAD dependent oxidoreductase ThiF PF00899.16 EGC35649.1 - 0.079 12.7 0.0 0.18 11.6 0.0 1.7 2 0 0 2 2 2 0 ThiF family Pyr_redox PF00070.22 EGC35649.1 - 0.12 12.7 0.2 1.8 9.0 0.0 2.6 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_3 PF13738.1 EGC35649.1 - 0.18 11.8 0.0 0.43 10.6 0.0 1.6 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase DUF2752 PF10825.3 EGC35653.1 - 0.016 15.2 0.1 0.036 14.0 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2752) Ded_cyto PF06920.8 EGC35654.1 - 8.6e-53 178.2 2.9 8.6e-53 178.2 2.0 3.4 3 0 0 3 3 3 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC35654.1 - 2e-45 154.6 3.7 7.7e-45 152.7 0.7 2.9 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins Usp PF00582.21 EGC35655.1 - 2.1e-22 79.8 0.0 2.6e-22 79.5 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Peripla_BP_5 PF13433.1 EGC35655.1 - 0.007 15.1 0.1 0.022 13.5 0.0 1.7 2 0 0 2 2 2 1 Periplasmic binding protein domain Oxidored_nitro PF00148.14 EGC35655.1 - 0.071 11.7 0.0 0.092 11.3 0.0 1.1 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase SBP_bac_3 PF00497.15 EGC35655.1 - 0.081 12.1 0.0 3.2 6.9 0.0 2.1 2 0 0 2 2 2 0 Bacterial extracellular solute-binding proteins, family 3 B12-binding PF02310.14 EGC35655.1 - 0.11 12.3 0.0 0.17 11.7 0.0 1.2 1 0 0 1 1 1 0 B12 binding domain Phosducin PF02114.11 EGC35656.1 - 2e-24 85.7 3.8 2.7e-21 75.4 0.2 2.3 1 1 1 2 2 2 2 Phosducin DUF4045 PF13254.1 EGC35656.1 - 0.31 10.2 8.7 0.43 9.8 6.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) PA14 PF07691.7 EGC35657.1 - 6.5e-09 35.5 0.0 1.3e-08 34.6 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC35657.1 - 0.0073 16.1 9.5 0.0073 16.1 6.6 10.8 12 1 0 12 12 12 5 Dictyostelium (slime mold) repeat Hemerythrin PF01814.18 EGC35658.1 - 0.21 11.7 7.6 13 5.9 1.3 3.8 2 1 1 3 3 3 0 Hemerythrin HHE cation binding domain MOR2-PAG1_N PF14222.1 EGC35659.1 - 3.8e-122 408.7 5.3 3.8e-122 408.7 3.6 2.8 3 0 0 3 3 3 1 Cell morphogenesis N-terminal MOR2-PAG1_mid PF14228.1 EGC35659.1 - 1.7e-67 227.9 9.8 4.8e-25 87.4 0.5 4.1 2 1 1 4 4 4 4 Cell morphogenesis central region MOR2-PAG1_C PF14225.1 EGC35659.1 - 8.2e-53 179.8 0.3 8.2e-53 179.8 0.2 3.4 4 0 0 4 4 4 1 Cell morphogenesis C-terminal Toxin_65 PF15543.1 EGC35659.1 - 0.044 13.4 0.0 0.098 12.2 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 65 NDK PF00334.14 EGC35660.1 - 7.5e-33 113.1 0.0 9.3e-33 112.8 0.0 1.1 1 0 0 1 1 1 1 Nucleoside diphosphate kinase Adenine_glyco PF03352.8 EGC35660.1 - 0.073 12.5 0.0 0.093 12.2 0.0 1.1 1 0 0 1 1 1 0 Methyladenine glycosylase BTB PF00651.26 EGC35662.1 - 4.8e-19 68.3 0.1 1.8e-18 66.5 0.0 2.0 2 0 0 2 2 2 1 BTB/POZ domain BACK PF07707.10 EGC35662.1 - 9.8e-06 25.3 0.1 0.00035 20.3 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch CDC45 PF02724.9 EGC35662.1 - 1.4 6.8 12.6 2.1 6.2 8.7 1.3 1 0 0 1 1 1 0 CDC45-like protein RRN3 PF05327.6 EGC35662.1 - 4 5.4 9.4 6 4.8 6.5 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Nop14 PF04147.7 EGC35662.1 - 8.9 4.0 24.3 13 3.5 16.9 1.1 1 0 0 1 1 1 0 Nop14-like family Terpene_synth_C PF03936.11 EGC35663.1 - 0.00037 19.7 0.1 0.00072 18.8 0.0 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain MFS_1 PF07690.11 EGC35664.1 - 2.1e-37 128.6 12.4 2.1e-37 128.6 8.6 2.0 2 1 0 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGC35664.1 - 7.2e-07 27.9 10.1 7.2e-07 27.9 7.0 2.9 2 2 1 3 3 3 2 MFS/sugar transport protein DUF4131 PF13567.1 EGC35664.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.0 4 0 0 4 4 4 0 Domain of unknown function (DUF4131) Rhomboid PF01694.17 EGC35665.1 - 1.7e-19 70.3 7.4 2.8e-19 69.5 5.1 1.3 1 0 0 1 1 1 1 Rhomboid family DUF1751 PF08551.5 EGC35665.1 - 0.069 13.4 0.1 0.14 12.5 0.1 1.6 1 0 0 1 1 1 0 Eukaryotic integral membrane protein (DUF1751) Syja_N PF02383.13 EGC35666.1 - 1.7e-83 280.0 5.2 1.7e-83 280.0 3.6 1.8 2 0 0 2 2 2 1 SacI homology domain Exo_endo_phos PF03372.18 EGC35666.1 - 3e-27 96.1 0.7 5.3e-27 95.3 0.5 1.4 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family RRM_1 PF00076.17 EGC35667.1 - 5.1e-26 90.1 3.3 2.6e-12 46.1 0.2 2.4 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35667.1 - 5.7e-20 71.0 0.2 1.4e-08 34.6 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35667.1 - 1.9e-05 24.4 2.5 0.071 12.9 0.0 3.1 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Sua5_yciO_yrdC PF01300.13 EGC35669.1 - 4.3e-46 156.4 0.0 7.9e-46 155.5 0.0 1.4 2 0 0 2 2 2 1 Telomere recombination SUA5 PF03481.8 EGC35669.1 - 6.9e-11 42.3 0.0 1.2e-10 41.5 0.0 1.4 1 0 0 1 1 1 1 Putative GTP-binding controlling metal-binding EGF_2 PF07974.8 EGC35670.1 - 0.00036 20.6 12.7 0.00036 20.6 8.8 3.5 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.19 EGC35670.1 - 0.00062 19.6 20.5 0.046 13.6 6.4 2.7 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) TIG PF01833.19 EGC35670.1 - 0.0016 18.3 4.1 0.0016 18.3 2.8 3.8 3 1 0 3 3 3 1 IPT/TIG domain Pepsin-I3 PF06394.8 EGC35671.1 - 0.01 15.4 0.1 0.029 14.0 0.1 1.8 1 0 0 1 1 1 0 Pepsin inhibitor-3-like repeated domain Pep3_Vps18 PF05131.9 EGC35671.1 - 0.018 14.4 1.1 0.055 12.8 0.8 1.8 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family HEPN PF05168.9 EGC35671.1 - 0.11 12.3 0.2 0.11 12.3 0.1 2.4 2 1 2 4 4 4 0 HEPN domain YjgP_YjgQ PF03739.9 EGC35671.1 - 2.1 7.0 6.4 3 6.4 4.4 1.3 1 0 0 1 1 1 0 Predicted permease YjgP/YjgQ family HATPase_c_3 PF13589.1 EGC35672.1 - 9.5e-07 28.5 6.4 0.014 15.0 0.7 3.9 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGC35673.1 - 1.2e-06 28.2 7.7 0.0031 17.1 1.2 3.6 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGC35674.1 - 1.6e-06 27.7 8.5 0.0029 17.2 1.7 3.3 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HEPN PF05168.9 EGC35674.1 - 0.00038 20.3 2.4 0.073 12.9 0.2 3.0 2 0 0 2 2 2 2 HEPN domain HATPase_c PF02518.21 EGC35674.1 - 0.0052 16.4 0.3 1.7 8.4 0.1 2.6 2 0 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGC35675.1 - 1.4e-06 27.9 7.9 0.005 16.5 1.6 3.3 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c PF02518.21 EGC35675.1 - 0.012 15.3 0.2 4.2 7.1 0.1 2.5 2 0 0 2 2 2 0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HATPase_c_3 PF13589.1 EGC35676.1 - 2.8e-05 23.7 7.9 0.061 12.9 1.2 3.8 2 2 0 2 2 2 2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase HAP1_N PF04849.8 EGC35677.1 - 0.00079 18.4 18.3 0.0011 17.9 12.7 1.2 1 0 0 1 1 1 1 HAP1 N-terminal conserved region bZIP_1 PF00170.16 EGC35677.1 - 0.00081 19.2 2.7 0.00081 19.2 1.9 2.3 2 0 0 2 2 1 1 bZIP transcription factor DUF869 PF05911.6 EGC35677.1 - 0.0087 14.3 15.0 0.011 14.0 10.4 1.0 1 0 0 1 1 1 1 Plant protein of unknown function (DUF869) COPIIcoated_ERV PF07970.7 EGC35677.1 - 0.012 15.2 0.1 0.013 15.0 0.1 1.3 1 0 0 1 1 1 0 Endoplasmic reticulum vesicle transporter MAD PF05557.8 EGC35677.1 - 0.014 13.5 17.3 0.02 12.9 12.0 1.2 1 0 0 1 1 1 0 Mitotic checkpoint protein Vfa1 PF08432.5 EGC35677.1 - 0.037 14.0 12.6 0.05 13.6 8.7 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Exonuc_VII_L PF02601.10 EGC35677.1 - 0.045 12.9 4.6 0.048 12.8 3.2 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit Tropomyosin_1 PF12718.2 EGC35677.1 - 0.27 11.0 23.9 0.094 12.5 3.5 2.1 1 1 1 2 2 2 0 Tropomyosin like ERM PF00769.14 EGC35677.1 - 0.33 10.4 20.5 1.6 8.2 14.0 1.8 1 1 0 1 1 1 0 Ezrin/radixin/moesin family DUF641 PF04859.7 EGC35677.1 - 0.35 10.6 17.3 1.4 8.6 4.3 2.2 1 1 1 2 2 2 0 Plant protein of unknown function (DUF641) Surfac_D-trimer PF09006.6 EGC35677.1 - 0.67 9.7 5.4 0.71 9.6 0.3 2.3 2 0 0 2 2 2 0 Lung surfactant protein D coiled-coil trimerisation DUF4200 PF13863.1 EGC35677.1 - 0.68 9.8 22.9 1.1 9.2 1.8 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) Flagellin_N PF00669.15 EGC35677.1 - 0.94 9.2 5.5 0.7 9.6 0.7 2.1 1 1 1 2 2 2 0 Bacterial flagellin N-terminal helical region ZapA PF05164.8 EGC35677.1 - 2.3 8.2 8.3 3.9 7.4 5.8 1.5 1 0 0 1 1 1 0 Cell division protein ZapA RasGAP_C PF03836.10 EGC35677.1 - 2.3 7.8 16.8 0.14 11.8 4.8 2.3 1 1 1 2 2 2 0 RasGAP C-terminus LCD1 PF09798.4 EGC35677.1 - 3.5 5.4 13.2 4.6 5.1 9.1 1.1 1 0 0 1 1 1 0 DNA damage checkpoint protein MCC-bdg_PDZ PF10506.4 EGC35677.1 - 3.9 7.3 9.2 0.39 10.5 1.7 2.2 2 0 0 2 2 2 0 PDZ domain of MCC-2 bdg protein for Usher syndrome PspB PF06667.7 EGC35677.1 - 4 7.4 12.8 9.3 6.2 0.8 3.1 2 1 1 3 3 3 0 Phage shock protein B FlaC_arch PF05377.6 EGC35677.1 - 4.8 7.1 7.3 1.2 9.0 0.7 2.3 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) Borrelia_P83 PF05262.6 EGC35677.1 - 4.9 5.3 14.9 6.2 4.9 10.3 1.0 1 0 0 1 1 1 0 Borrelia P83/100 protein Fib_alpha PF08702.5 EGC35677.1 - 5 7.2 15.1 8.7 6.4 10.4 1.4 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Tnp_P_element PF12017.3 EGC35677.1 - 5.3 6.2 12.3 0.99 8.5 2.4 2.1 2 0 0 2 2 2 0 Transposase protein TBPIP PF07106.8 EGC35677.1 - 5.6 6.4 19.7 2.7 7.5 2.3 2.2 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Spc7 PF08317.6 EGC35677.1 - 6.9 5.2 21.3 15 4.1 14.8 1.5 1 1 0 1 1 1 0 Spc7 kinetochore protein DivIVA PF05103.8 EGC35677.1 - 8 6.5 18.4 13 5.8 12.3 1.6 1 1 1 2 2 2 0 DivIVA protein DUF1664 PF07889.7 EGC35677.1 - 9.3 6.0 9.7 26 4.6 6.7 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) Pkinase PF00069.20 EGC35678.1 - 4.2e-72 242.4 0.6 7.9e-72 241.5 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35678.1 - 5.4e-53 179.6 0.0 1e-52 178.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC35678.1 - 1.1e-05 24.5 0.0 2.7e-05 23.2 0.0 1.6 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC35678.1 - 0.0028 16.7 0.1 0.0053 15.8 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family zf-ribbon_3 PF13248.1 EGC35679.1 - 0.0042 16.2 2.4 0.0074 15.4 1.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EGC35679.1 - 0.059 13.1 1.1 0.11 12.3 0.7 1.4 1 0 0 1 1 1 0 Double zinc ribbon RhoGEF PF00621.15 EGC35681.1 - 4.4e-35 121.1 4.8 4.4e-35 121.1 3.3 2.9 3 1 0 3 3 3 1 RhoGEF domain PH PF00169.24 EGC35681.1 - 0.0021 18.2 2.8 0.0021 18.2 2.0 3.2 2 2 0 2 2 2 1 PH domain PH_9 PF15410.1 EGC35681.1 - 0.0073 16.4 1.2 0.0073 16.4 0.9 2.1 2 0 0 2 2 2 1 Pleckstrin homology domain MADF_DNA_bdg PF10545.4 EGC35681.1 - 0.12 12.5 6.9 0.93 9.7 0.0 4.0 3 1 1 4 4 4 0 Alcohol dehydrogenase transcription factor Myb/SANT-like Actin PF00022.14 EGC35682.1 - 8.1e-163 541.4 0.0 9.2e-163 541.2 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC35682.1 - 0.084 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) ETRAMP PF09716.5 EGC35684.1 - 0.044 13.7 4.4 0.15 12.0 3.0 2.0 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF1191 PF06697.7 EGC35684.1 - 0.074 11.8 0.0 0.098 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) Tetraspannin PF00335.15 EGC35684.1 - 2.1 7.5 6.9 0.24 10.6 0.3 1.9 1 1 1 2 2 2 0 Tetraspanin family UCH PF00443.24 EGC35685.1 - 7.6e-05 21.9 0.5 9.8e-05 21.5 0.3 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH PF00443.24 EGC35686.1 - 4.1e-07 29.3 0.1 8.4e-07 28.3 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase TRAPP PF04051.11 EGC35688.1 - 3.2e-40 137.1 0.4 4.4e-40 136.6 0.3 1.2 1 0 0 1 1 1 1 Transport protein particle (TRAPP) component Brix PF04427.13 EGC35689.1 - 2.6e-49 167.4 0.3 3.5e-49 167.0 0.2 1.1 1 0 0 1 1 1 1 Brix domain Bromodomain PF00439.20 EGC35689.1 - 0.1 12.5 0.0 0.31 10.9 0.0 1.9 2 0 0 2 2 2 0 Bromodomain DUF3863 PF12979.2 EGC35690.1 - 0.017 13.7 0.1 0.021 13.4 0.1 1.1 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) DUF357 PF04010.8 EGC35690.1 - 0.19 11.4 2.5 1.2 8.9 1.7 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF357) RasGEF PF00617.14 EGC35693.1 - 1.3e-61 207.6 5.5 1.8e-61 207.1 1.0 2.9 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC35693.1 - 6.3e-23 80.8 0.7 6.3e-23 80.8 0.5 5.3 5 1 0 5 5 5 1 RasGEF N-terminal motif zf-RING_2 PF13639.1 EGC35694.1 - 4.3e-09 36.0 15.3 7e-09 35.3 10.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC35694.1 - 3.2e-07 29.9 13.7 5.7e-07 29.1 9.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC35694.1 - 1.5e-05 25.0 9.3 3.4e-05 23.8 6.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC35694.1 - 0.00045 20.1 18.1 0.00079 19.4 12.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC35694.1 - 0.0008 19.0 18.1 0.0016 18.0 12.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC35694.1 - 0.034 13.8 15.6 0.062 13.0 10.8 1.4 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGC35694.1 - 0.21 11.4 7.4 0.42 10.4 5.1 1.4 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Asp-B-Hydro_N PF05279.6 EGC35694.1 - 2.5 7.8 17.0 5.1 6.8 11.8 1.5 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Radical_SAM PF04055.16 EGC35695.1 - 7.4e-18 65.2 0.0 2.4e-17 63.6 0.0 1.8 1 0 0 1 1 1 1 Radical SAM superfamily Acetyltransf_1 PF00583.19 EGC35695.1 - 3.4e-13 49.4 0.1 7.8e-13 48.2 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGC35695.1 - 0.015 14.9 0.0 0.037 13.7 0.0 1.6 1 0 0 1 1 1 0 FR47-like protein Acetyltransf_10 PF13673.1 EGC35695.1 - 0.034 14.2 0.1 0.075 13.1 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Glyco_hydro_42 PF02449.10 EGC35695.1 - 0.043 12.9 0.0 0.066 12.3 0.0 1.2 1 0 0 1 1 1 0 Beta-galactosidase PA14 PF07691.7 EGC35696.1 - 2.8e-14 52.9 0.0 4.3e-14 52.3 0.0 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC35696.1 - 3.1e-06 26.8 6.1 3.1e-06 26.8 4.2 7.3 7 1 1 8 8 8 2 Dictyostelium (slime mold) repeat ATP-synt_J PF04911.7 EGC35698.1 - 0.071 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 ATP synthase j chain HLH PF00010.21 EGC35699.1 - 0.0059 16.2 0.5 0.01 15.5 0.4 1.4 1 0 0 1 1 1 1 Helix-loop-helix DNA-binding domain Elong-fact-P_C PF09285.6 EGC35699.1 - 0.098 12.0 0.2 0.15 11.4 0.1 1.2 1 0 0 1 1 1 0 Elongation factor P, C-terminal RNB PF00773.14 EGC35700.1 - 3.4e-22 79.1 4.8 3.4e-22 79.1 3.3 5.9 6 0 0 6 6 6 2 RNB domain AAA_19 PF13245.1 EGC35700.1 - 0.0019 17.9 0.0 0.0035 17.0 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain PhoH PF02562.11 EGC35700.1 - 0.011 14.9 0.0 0.027 13.7 0.0 1.6 1 0 0 1 1 1 0 PhoH-like protein AAA_17 PF13207.1 EGC35700.1 - 0.048 14.4 0.5 0.36 11.6 0.1 2.8 2 0 0 2 2 2 0 AAA domain T2SE PF00437.15 EGC35700.1 - 0.083 11.7 0.2 0.15 10.9 0.1 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein RuvB_N PF05496.7 EGC35700.1 - 0.17 10.9 0.0 0.31 10.0 0.0 1.3 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_30 PF13604.1 EGC35700.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.2 1 0 0 1 1 1 0 AAA domain DUF1771 PF08590.5 EGC35701.1 - 2.4e-07 30.6 4.6 2.4e-07 30.6 2.4 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF1771) Smr PF01713.16 EGC35701.1 - 2.4e-07 30.8 0.1 1.1e-06 28.7 0.0 2.2 2 1 0 2 2 2 1 Smr domain CUE PF02845.11 EGC35701.1 - 0.0095 15.4 0.0 0.026 14.0 0.0 1.7 1 0 0 1 1 1 1 CUE domain DMA PF03474.9 EGC35701.1 - 0.034 13.9 0.1 0.14 11.9 0.0 2.1 2 0 0 2 2 2 0 DMRTA motif zf-CCCH PF00642.19 EGC35701.1 - 0.071 12.8 0.2 0.071 12.8 0.1 3.2 3 1 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGC35701.1 - 0.35 10.9 19.4 2.6 8.1 1.3 3.8 3 0 0 3 3 3 0 Zinc finger C-x8-C-x5-C-x3-H type Pex14_N PF04695.8 EGC35701.1 - 5.3 7.1 9.7 14 5.7 6.7 1.7 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region LMF1 PF06762.9 EGC35702.1 - 8.4e-128 426.4 11.8 8.4e-128 426.4 8.2 2.0 3 0 0 3 3 3 1 Lipase maturation factor Chromo PF00385.19 EGC35704.1 - 3.1e-15 55.5 1.6 3.7e-15 55.3 1.1 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC35704.1 - 0.074 12.7 0.3 0.11 12.2 0.2 1.4 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Aminotran_5 PF00266.14 EGC35705.1 - 0.0063 15.2 0.0 0.007 15.1 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V Abhydrolase_5 PF12695.2 EGC35706.1 - 0.02 14.6 0.0 0.036 13.8 0.0 1.4 1 1 0 1 1 1 0 Alpha/beta hydrolase family Mt_ATP-synt_D PF05873.7 EGC35707.1 - 0.0057 16.3 1.8 0.0067 16.0 1.0 1.4 1 1 0 1 1 1 1 ATP synthase D chain, mitochondrial (ATP5H) 2OG-FeII_Oxy PF03171.15 EGC35708.1 - 8.8e-10 38.7 0.0 1.2e-09 38.2 0.0 1.2 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_3 PF13640.1 EGC35708.1 - 9.9e-09 35.6 0.0 1.7e-08 34.9 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy_4 PF13661.1 EGC35708.1 - 0.092 12.3 0.0 0.16 11.6 0.0 1.3 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily SNARE PF05739.14 EGC35709.1 - 1.7e-08 33.9 3.9 2.1e-08 33.7 0.3 2.1 1 1 1 2 2 2 1 SNARE domain Use1 PF09753.4 EGC35709.1 - 0.034 13.5 0.3 0.037 13.4 0.2 1.1 1 0 0 1 1 1 0 Membrane fusion protein Use1 Vip3A_N PF12495.3 EGC35709.1 - 0.042 13.5 0.3 0.053 13.2 0.2 1.1 1 0 0 1 1 1 0 Vegetative insecticide protein 3A N terminal DUF1139 PF06599.6 EGC35709.1 - 0.05 12.7 0.3 0.055 12.6 0.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1139) Laminin_II PF06009.7 EGC35709.1 - 0.19 11.4 2.9 0.22 11.2 0.5 1.9 1 1 1 2 2 2 0 Laminin Domain II Phage_Gp23 PF10669.4 EGC35709.1 - 2.6 8.1 5.8 0.15 12.1 0.4 1.7 2 0 0 2 2 2 0 Protein gp23 (Bacteriophage A118) Mit_KHE1 PF10173.4 EGC35710.1 - 7.6e-41 140.0 4.0 7.6e-41 140.0 2.8 1.9 2 0 0 2 2 2 1 Mitochondrial K+-H+ exchange-related Mucin PF01456.12 EGC35710.1 - 7.4 6.3 10.3 2.7 7.7 3.2 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein CRF1 PF10380.4 EGC35710.1 - 8.4 6.7 8.6 0.29 11.4 1.2 2.0 2 1 0 2 2 2 0 Transcription factor CRF1 Pkinase PF00069.20 EGC35711.1 - 1.4e-61 207.9 0.0 2.7e-61 206.9 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35711.1 - 1.1e-44 152.5 0.0 1.8e-44 151.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Peptidase_M16 PF00675.15 EGC35711.1 - 1.1e-33 116.0 0.0 3.7e-33 114.3 0.0 1.9 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGC35711.1 - 9.4e-25 87.3 8.4 1.4e-14 54.2 0.2 4.3 3 1 1 4 4 4 2 Peptidase M16 inactive domain APH PF01636.18 EGC35711.1 - 0.062 13.0 0.0 0.12 12.0 0.0 1.4 1 0 0 1 1 1 0 Phosphotransferase enzyme family F-box-like PF12937.2 EGC35712.1 - 2.3e-05 24.0 0.1 5.3e-05 22.8 0.1 1.6 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC35712.1 - 0.00034 20.1 0.0 0.001 18.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain Cob_adeno_trans PF01923.13 EGC35712.1 - 0.044 13.5 0.0 0.13 12.0 0.0 1.7 1 0 0 1 1 1 0 Cobalamin adenosyltransferase F-box-like PF12937.2 EGC35713.1 - 5.5e-05 22.8 0.1 0.00013 21.5 0.1 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC35713.1 - 0.00075 19.0 0.0 0.0022 17.6 0.0 1.8 1 0 0 1 1 1 1 F-box domain TIG PF01833.19 EGC35714.1 - 5e-07 29.6 8.5 0.009 15.9 0.1 3.5 2 1 1 3 3 3 2 IPT/TIG domain DUF4448 PF14610.1 EGC35714.1 - 0.00011 21.7 0.3 0.00038 19.9 0.2 2.0 1 1 0 1 1 1 1 Protein of unknown function (DUF4448) TMEM154 PF15102.1 EGC35714.1 - 0.0012 18.5 1.6 0.0015 18.2 0.2 1.9 2 0 0 2 2 2 1 TMEM154 protein family DUF4064 PF13273.1 EGC35714.1 - 0.0034 17.4 2.1 0.0091 16.0 0.4 2.4 3 0 0 3 3 3 1 Protein of unknown function (DUF4064) DUF4519 PF15012.1 EGC35714.1 - 0.025 14.4 0.1 0.061 13.2 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) Syndecan PF01034.15 EGC35714.1 - 0.051 13.2 0.1 0.13 11.9 0.1 1.7 1 0 0 1 1 1 0 Syndecan domain Choline_transpo PF04515.7 EGC35715.1 - 0.029 13.1 5.2 0.033 12.9 3.6 1.0 1 0 0 1 1 1 0 Plasma-membrane choline transporter DUF3165 PF11364.3 EGC35715.1 - 0.068 13.2 5.7 1.1 9.4 0.6 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3165) MFS_Mycoplasma PF07672.8 EGC35715.1 - 0.08 12.1 3.2 0.085 12.0 2.2 1.0 1 0 0 1 1 1 0 Mycoplasma MFS transporter DUF1240 PF06836.7 EGC35715.1 - 0.65 10.2 6.3 1.1 9.5 4.4 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1240) GMP_synt_C PF00958.17 EGC35716.1 - 4.2e-30 103.3 0.0 2.9e-19 68.5 0.0 2.6 2 0 0 2 2 2 2 GMP synthase C terminal domain NAD_synthase PF02540.12 EGC35716.1 - 0.053 12.4 0.0 0.09 11.6 0.0 1.4 1 0 0 1 1 1 0 NAD synthase SART-1 PF03343.8 EGC35717.1 - 8.5e-83 278.7 108.6 8.5e-83 278.7 75.3 3.0 2 1 0 2 2 2 1 SART-1 family CPSF_A PF03178.10 EGC35718.1 - 9.6e-80 268.0 1.3 7.4e-79 265.1 0.5 2.4 2 0 0 2 2 2 1 CPSF A subunit region DUF3483 PF11982.3 EGC35718.1 - 0.61 9.3 0.0 0.98 8.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3483) CAP PF00188.21 EGC35719.1 - 5e-07 30.2 0.4 5e-07 30.2 0.2 1.9 3 0 0 3 3 3 1 Cysteine-rich secretory protein family PLRV_ORF5 PF01690.12 EGC35720.1 - 3 6.8 21.5 3.9 6.5 14.9 1.0 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Chromo PF00385.19 EGC35721.1 - 7.1e-14 51.2 0.9 2.5e-13 49.4 0.6 2.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Draxin PF15550.1 EGC35721.1 - 5.5e-05 22.9 20.4 8.1e-05 22.4 14.2 1.2 1 0 0 1 1 1 1 Draxin CutA1 PF03091.10 EGC35721.1 - 0.011 15.3 1.6 0.029 14.0 0.0 2.2 2 0 0 2 2 2 0 CutA1 divalent ion tolerance protein PAT1 PF09770.4 EGC35721.1 - 0.97 7.5 34.9 1.3 7.2 24.2 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Chromo PF00385.19 EGC35722.1 - 3.6e-15 55.3 1.7 3.9e-15 55.2 1.2 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC35722.1 - 0.075 12.7 0.3 0.11 12.2 0.2 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain zf-C3HC4_3 PF13920.1 EGC35723.1 - 4.6e-08 32.6 8.0 7.5e-08 31.9 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC35723.1 - 1.9e-07 30.7 9.0 3.2e-07 30.0 6.2 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC35723.1 - 2.1e-07 30.4 9.6 4e-07 29.5 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC35723.1 - 3.3e-06 27.1 6.4 7.7e-06 25.9 4.5 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC35723.1 - 1.4e-05 25.0 9.7 2.3e-05 24.3 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC35723.1 - 0.002 17.7 8.9 0.0036 16.9 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC35723.1 - 0.0053 16.6 8.6 0.019 14.8 5.9 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC35723.1 - 0.13 11.9 2.8 0.4 10.4 1.9 1.8 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EGC35723.1 - 0.21 11.4 7.4 2.8 7.8 5.0 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EGC35723.1 - 0.42 10.2 12.2 8 6.1 8.3 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Zn_ribbon_2 PF12674.2 EGC35723.1 - 0.43 10.9 4.7 0.26 11.6 1.1 2.4 2 0 0 2 2 2 0 Putative zinc ribbon domain Ank_2 PF12796.2 EGC35725.1 - 1.1e-06 28.9 0.4 0.022 15.1 0.1 4.2 4 1 0 4 4 4 2 Ankyrin repeats (3 copies) DUF3439 PF11921.3 EGC35725.1 - 0.00081 19.1 7.8 0.00081 19.1 5.4 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC35725.1 - 0.32 10.7 36.2 1.3 8.7 11.4 2.6 2 0 0 2 2 2 0 Mucin-like glycoprotein Pkinase PF00069.20 EGC35726.1 - 1.1e-54 185.3 0.0 1.3e-54 185.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35726.1 - 4.5e-23 81.6 0.0 7.4e-23 80.9 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC35726.1 - 0.0067 16.1 0.0 0.019 14.7 0.0 1.7 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC35726.1 - 0.068 12.2 0.0 0.1 11.6 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC35726.1 - 0.083 12.2 0.0 0.17 11.2 0.0 1.5 1 1 0 1 1 1 0 RIO1 family Ribosomal_S5 PF00333.15 EGC35727.1 - 2e-29 101.1 3.0 3.1e-29 100.5 2.1 1.3 1 0 0 1 1 1 1 Ribosomal protein S5, N-terminal domain Ribosomal_S5_C PF03719.10 EGC35727.1 - 4.2e-23 80.4 0.1 8.4e-23 79.4 0.0 1.5 1 0 0 1 1 1 1 Ribosomal protein S5, C-terminal domain PC_rep PF01851.17 EGC35728.1 - 3.4e-21 74.1 21.6 2.6e-06 27.3 0.0 9.0 8 0 0 8 8 8 4 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGC35728.1 - 3e-08 33.8 1.6 0.091 13.0 0.0 3.9 4 0 0 4 4 4 3 HEAT repeats HEAT PF02985.17 EGC35728.1 - 0.00018 21.3 0.0 3.7 7.8 0.0 4.0 3 0 0 3 3 3 1 HEAT repeat HEAT_EZ PF13513.1 EGC35728.1 - 0.00039 20.8 4.0 8.6 7.0 0.0 4.6 3 1 1 4 4 4 2 HEAT-like repeat Utp13 PF08625.6 EGC35728.1 - 0.055 13.1 0.2 0.34 10.5 0.1 2.5 2 0 0 2 2 2 0 Utp13 specific WD40 associated domain DUF707 PF05212.7 EGC35728.1 - 0.071 12.2 0.0 0.14 11.2 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF707) Ank_4 PF13637.1 EGC35730.1 - 1.3e-05 25.5 1.1 0.0064 16.9 0.0 4.6 4 1 0 4 4 4 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC35730.1 - 0.00013 22.2 0.0 0.041 14.2 0.0 3.4 2 1 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC35730.1 - 0.00067 19.6 0.7 3 8.3 0.0 4.9 6 0 0 6 6 6 2 Ankyrin repeat Complex1_LYR_1 PF13232.1 EGC35732.1 - 1.4e-08 34.8 1.1 2e-08 34.3 0.7 1.3 1 0 0 1 1 1 1 Complex1_LYR-like Complex1_LYR PF05347.10 EGC35732.1 - 7.4e-08 32.0 0.7 1.2e-07 31.4 0.5 1.4 1 0 0 1 1 1 1 Complex 1 protein (LYR family) TraD_N PF12615.3 EGC35732.1 - 0.0048 17.2 0.0 0.0069 16.7 0.0 1.2 1 0 0 1 1 1 1 F sex factor protein N terminal Peptidase_M4 PF01447.13 EGC35732.1 - 0.036 14.1 0.1 0.047 13.8 0.1 1.2 1 0 0 1 1 1 0 Thermolysin metallopeptidase, catalytic domain DUF4416 PF14385.1 EGC35732.1 - 0.074 12.7 0.9 0.11 12.2 0.6 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4416) GHMP_kinases_N PF00288.21 EGC35733.1 - 2.1e-05 24.4 0.4 7.2e-05 22.7 0.3 2.0 1 0 0 1 1 1 1 GHMP kinases N terminal domain CBF PF03914.12 EGC35734.1 - 1e-27 96.6 0.7 8.5e-27 93.6 0.0 2.8 2 0 0 2 2 2 1 CBF/Mak21 family NOC3p PF07540.6 EGC35734.1 - 2e-20 72.8 5.3 2e-20 72.8 3.7 3.6 3 1 0 3 3 3 1 Nucleolar complex-associated protein Swi5 PF07061.6 EGC35735.1 - 4.2e-11 42.4 6.4 7.1e-11 41.7 4.5 1.3 1 0 0 1 1 1 1 Swi5 DUF904 PF06005.7 EGC35735.1 - 0.00017 21.7 4.7 0.00017 21.7 3.3 1.7 2 0 0 2 2 1 1 Protein of unknown function (DUF904) TMF_DNA_bd PF12329.3 EGC35735.1 - 0.00035 20.3 7.3 0.00035 20.3 5.1 2.3 1 1 0 2 2 2 1 TATA element modulatory factor 1 DNA binding SCP-1 PF05483.7 EGC35735.1 - 0.00075 17.4 8.6 0.00075 17.4 6.0 1.1 1 0 0 1 1 1 1 Synaptonemal complex protein 1 (SCP-1) Laminin_I PF06008.9 EGC35735.1 - 0.00084 18.7 5.5 0.00096 18.5 3.8 1.1 1 0 0 1 1 1 1 Laminin Domain I TBPIP PF07106.8 EGC35735.1 - 0.00093 18.7 7.7 0.00093 18.7 5.3 1.4 1 1 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) GAS PF13851.1 EGC35735.1 - 0.0042 16.3 11.3 0.0049 16.0 7.8 1.2 1 0 0 1 1 1 1 Growth-arrest specific micro-tubule binding FliD_N PF02465.13 EGC35735.1 - 0.006 16.9 1.0 1.1 9.7 0.1 2.3 1 1 1 2 2 2 1 Flagellar hook-associated protein 2 N-terminus DUF2968 PF11180.3 EGC35735.1 - 0.0067 15.8 1.3 0.0081 15.5 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2968) IncA PF04156.9 EGC35735.1 - 0.0096 15.5 6.1 0.011 15.2 4.2 1.1 1 0 0 1 1 1 1 IncA protein DUF4208 PF13907.1 EGC35735.1 - 0.012 15.7 1.6 0.019 15.1 1.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4208) Laminin_II PF06009.7 EGC35735.1 - 0.012 15.3 0.9 0.012 15.3 0.6 1.5 2 0 0 2 2 1 0 Laminin Domain II Rho_Binding PF08912.6 EGC35735.1 - 0.013 15.7 6.2 0.032 14.5 4.3 1.6 1 0 0 1 1 1 0 Rho Binding Spectrin PF00435.16 EGC35735.1 - 0.018 15.2 5.2 0.023 14.9 3.6 1.3 1 0 0 1 1 1 0 Spectrin repeat Mnd1 PF03962.10 EGC35735.1 - 0.019 14.6 5.4 0.022 14.4 3.7 1.2 1 0 0 1 1 1 0 Mnd1 family DUF4140 PF13600.1 EGC35735.1 - 0.02 15.3 1.4 0.035 14.5 1.0 1.4 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) FTA4 PF13093.1 EGC35735.1 - 0.02 14.3 3.5 0.021 14.2 2.4 1.1 1 0 0 1 1 1 0 Kinetochore complex Fta4 of Sim4 subunit, or CENP-50 Apt1 PF10351.4 EGC35735.1 - 0.022 13.6 3.1 0.022 13.6 2.1 1.1 1 0 0 1 1 1 0 Golgi-body localisation protein domain Spc7 PF08317.6 EGC35735.1 - 0.027 13.1 8.1 0.031 12.9 5.6 1.1 1 0 0 1 1 1 0 Spc7 kinetochore protein HycH PF07450.6 EGC35735.1 - 0.041 13.9 1.0 1.3 9.1 0.0 2.1 1 1 1 2 2 2 0 Formate hydrogenlyase maturation protein HycH DUF342 PF03961.8 EGC35735.1 - 0.041 12.2 9.4 0.052 11.9 6.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF342) MRP-S27 PF10037.4 EGC35735.1 - 0.045 12.6 2.6 0.047 12.6 1.8 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S27 GrpE PF01025.14 EGC35735.1 - 0.046 13.2 6.3 0.055 13.0 4.2 1.3 1 1 0 1 1 1 0 GrpE Mac PF12464.3 EGC35735.1 - 0.046 13.7 1.0 0.088 12.8 0.4 1.7 1 1 0 1 1 1 0 Maltose acetyltransferase ADIP PF11559.3 EGC35735.1 - 0.046 13.6 7.0 0.072 12.9 4.5 1.6 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding Cauli_AT PF03233.8 EGC35735.1 - 0.058 13.1 5.3 0.085 12.5 3.7 1.3 1 0 0 1 1 1 0 Aphid transmission protein APG6 PF04111.7 EGC35735.1 - 0.063 12.3 6.8 0.065 12.2 4.7 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 Atg14 PF10186.4 EGC35735.1 - 0.067 12.1 4.4 0.074 11.9 3.0 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Herpes_UL6 PF01763.11 EGC35735.1 - 0.081 11.0 2.1 0.087 10.9 1.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL6 like Viral_P18 PF04521.8 EGC35735.1 - 0.095 12.1 1.1 0.15 11.5 0.8 1.4 1 0 0 1 1 1 0 ssRNA positive strand viral 18kD cysteine rich protein Prefoldin_2 PF01920.15 EGC35735.1 - 0.12 12.1 7.6 0.21 11.3 3.7 2.3 1 1 0 2 2 2 0 Prefoldin subunit DUF3373 PF11853.3 EGC35735.1 - 0.13 10.7 3.1 0.14 10.6 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) T2SM PF04612.7 EGC35735.1 - 0.14 11.9 0.5 0.34 10.6 0.3 1.6 1 1 1 2 2 2 0 Type II secretion system (T2SS), protein M bZIP_1 PF00170.16 EGC35735.1 - 0.15 12.0 2.2 0.42 10.5 1.5 1.8 1 0 0 1 1 1 0 bZIP transcription factor HAUS6_N PF14661.1 EGC35735.1 - 0.15 11.3 2.9 0.17 11.2 2.0 1.2 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus GIDA_assoc_3 PF13932.1 EGC35735.1 - 0.17 11.9 2.8 0.96 9.5 0.1 2.2 1 1 1 2 2 2 0 GidA associated domain 3 NPV_P10 PF05531.7 EGC35735.1 - 0.19 12.0 2.1 0.6 10.4 1.2 2.0 1 1 1 2 2 2 0 Nucleopolyhedrovirus P10 protein NdhM PF10664.4 EGC35735.1 - 0.21 11.5 1.6 0.28 11.0 1.1 1.3 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DUF848 PF05852.6 EGC35735.1 - 0.24 11.2 3.6 0.29 10.9 2.5 1.3 1 0 0 1 1 1 0 Gammaherpesvirus protein of unknown function (DUF848) DUF4200 PF13863.1 EGC35735.1 - 0.29 11.0 9.8 0.081 12.8 2.7 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4200) DUF2681 PF10883.3 EGC35735.1 - 0.34 11.1 3.5 0.54 10.4 2.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) DUF724 PF05266.9 EGC35735.1 - 0.34 10.4 5.8 0.43 10.1 4.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF724) Z1 PF10593.4 EGC35735.1 - 0.35 10.0 2.4 0.41 9.8 1.7 1.2 1 0 0 1 1 1 0 Z1 domain SlyX PF04102.7 EGC35735.1 - 0.42 11.0 4.7 0.79 10.1 2.2 2.1 1 1 1 2 2 2 0 SlyX DivIVA PF05103.8 EGC35735.1 - 0.48 10.4 7.2 3.4 7.7 4.9 2.1 1 1 1 2 2 2 0 DivIVA protein DivIC PF04977.10 EGC35735.1 - 0.58 9.6 7.3 0.91 9.0 4.4 1.9 1 1 0 1 1 1 0 Septum formation initiator LON PF02190.11 EGC35735.1 - 0.63 9.6 3.3 0.97 9.0 2.3 1.5 1 1 0 1 1 1 0 ATP-dependent protease La (LON) domain Prefoldin PF02996.12 EGC35735.1 - 0.68 9.5 7.2 0.31 10.7 2.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit V_ATPase_I PF01496.14 EGC35735.1 - 0.75 7.5 4.7 0.81 7.4 3.3 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family FlxA PF14282.1 EGC35735.1 - 0.79 9.7 7.9 3.1 7.7 5.5 2.1 1 1 0 1 1 1 0 FlxA-like protein DUF3498 PF12004.3 EGC35735.1 - 0.89 8.6 5.2 0.96 8.5 3.6 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3498) Syntaxin-6_N PF09177.6 EGC35735.1 - 1.2 9.6 6.6 2.7 8.4 0.6 2.6 1 1 1 2 2 2 0 Syntaxin 6, N-terminal DUF4164 PF13747.1 EGC35735.1 - 1.3 9.2 6.2 3.7 7.7 2.9 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4164) KilA-N PF04383.8 EGC35735.1 - 2.2 7.9 6.2 2.6 7.6 4.3 1.4 1 1 0 1 1 1 0 KilA-N domain Syntaxin PF00804.20 EGC35735.1 - 4.9 7.3 8.8 4.1 7.6 4.3 2.2 1 1 1 2 2 1 0 Syntaxin Snapin_Pallidin PF14712.1 EGC35735.1 - 5.3 7.4 8.7 1.1 9.6 3.3 1.9 2 1 1 3 3 2 0 Snapin/Pallidin DUF919 PF06034.6 EGC35735.1 - 5.5 6.6 9.0 1.3 8.7 3.5 2.2 2 1 0 2 2 1 0 Nucleopolyhedrovirus protein of unknown function (DUF919) DUF2678 PF10856.3 EGC35736.1 - 0.048 13.3 3.1 7.6 6.2 0.1 3.5 3 0 0 3 3 3 0 Protein of unknown function (DUF2678) EGF_2 PF07974.8 EGC35737.1 - 1.2 9.3 12.6 0.27 11.4 6.3 1.8 2 0 0 2 2 2 0 EGF-like domain AMP-binding PF00501.23 EGC35738.1 - 1.2e-81 274.2 0.1 1.2e-81 274.2 0.0 2.1 3 0 0 3 3 3 1 AMP-binding enzyme Cas_Cas2CT1978 PF09707.5 EGC35738.1 - 0.008 16.0 0.0 0.021 14.7 0.0 1.7 1 0 0 1 1 1 1 CRISPR-associated protein (Cas_Cas2CT1978) Pyr_redox_2 PF07992.9 EGC35739.1 - 2.4e-22 79.8 0.0 3.8e-22 79.1 0.0 1.5 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC35739.1 - 1.3e-10 41.5 0.1 9.8e-08 32.3 0.1 3.7 3 1 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase APG5 PF04106.7 EGC35739.1 - 0.014 14.8 0.0 0.033 13.6 0.0 1.5 1 0 0 1 1 1 0 Autophagy protein Apg5 Proteasome PF00227.21 EGC35740.1 - 2.8e-49 166.9 0.1 3.5e-49 166.6 0.1 1.1 1 0 0 1 1 1 1 Proteasome subunit Band_7 PF01145.20 EGC35741.1 - 3.1e-05 23.9 10.7 0.00046 20.1 7.4 2.2 1 1 0 1 1 1 1 SPFH domain / Band 7 family Glyco_hydro_7 PF00840.15 EGC35742.1 - 1.8e-205 682.3 16.5 2.1e-205 682.0 11.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 7 Sdh5 PF03937.11 EGC35743.1 - 3.4e-24 84.3 0.4 5e-24 83.7 0.3 1.2 1 0 0 1 1 1 1 Flavinator of succinate dehydrogenase Rubredoxin PF00301.15 EGC35744.1 - 1.5 8.7 6.3 0.22 11.4 0.1 2.9 3 0 0 3 3 3 0 Rubredoxin Claudin_2 PF13903.1 EGC35747.1 - 0.0004 20.1 0.8 0.00062 19.4 0.0 1.6 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction DUF3501 PF12007.3 EGC35747.1 - 0.018 14.7 0.1 0.023 14.3 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3501) DUF912 PF06024.7 EGC35747.1 - 7.8 6.6 12.7 4.6 7.3 0.4 2.8 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1436 PF07262.6 EGC35748.1 - 0.021 14.3 0.9 0.027 13.9 0.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1436) hSac2 PF12456.3 EGC35748.1 - 0.062 12.6 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Inositol phosphatase Ribosomal_S8 PF00410.14 EGC35749.1 - 6.4e-24 84.2 0.0 7.7e-24 83.9 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S8 BBS2_Mid PF14783.1 EGC35750.1 - 2.3e-08 33.7 1.4 9.5e-06 25.3 0.1 3.1 3 0 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Rap_GAP PF02145.10 EGC35751.1 - 6.4e-66 221.3 0.1 1.4e-65 220.2 0.1 1.6 1 0 0 1 1 1 1 Rap/ran-GAP Mucin PF01456.12 EGC35751.1 - 0.0082 15.9 10.8 0.0082 15.9 7.5 2.0 2 0 0 2 2 2 1 Mucin-like glycoprotein DUF3028 PF11229.3 EGC35751.1 - 0.04 12.2 0.1 0.061 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3028) DUF3439 PF11921.3 EGC35751.1 - 0.35 10.6 10.3 0.98 9.1 7.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DEAD PF00270.24 EGC35752.1 - 4.2e-19 68.6 1.9 1.8e-17 63.3 0.0 2.5 1 1 1 2 2 2 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC35752.1 - 1.9e-08 34.0 0.0 5.8e-08 32.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF962 PF06127.6 EGC35753.1 - 3.4e-35 119.8 0.5 3.8e-35 119.6 0.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF962) Glyco_hydro_2 PF00703.16 EGC35754.1 - 6.9e-08 32.9 2.2 3e-07 30.8 0.0 2.8 3 0 0 3 3 3 1 Glycosyl hydrolases family 2 Glyco_hydro_2_C PF02836.12 EGC35754.1 - 8.2e-05 21.6 0.3 0.00018 20.5 0.0 1.6 2 0 0 2 2 2 1 Glycosyl hydrolases family 2, TIM barrel domain DIOX_N PF14226.1 EGC35755.1 - 1.9e-05 25.1 0.0 4.6e-05 23.9 0.0 1.6 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC35755.1 - 0.015 15.5 0.0 0.036 14.3 0.0 1.7 1 0 0 1 1 1 0 2OG-Fe(II) oxygenase superfamily Aldedh PF00171.17 EGC35756.1 - 2.2e-121 405.4 0.0 2.8e-121 405.1 0.0 1.1 1 0 0 1 1 1 1 Aldehyde dehydrogenase family LuxC PF05893.9 EGC35756.1 - 2.6e-07 29.7 0.2 4.2e-07 29.0 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA reductase (LuxC) DUF2185 PF09951.4 EGC35756.1 - 0.099 12.4 0.1 0.32 10.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2185) Erf4 PF10256.4 EGC35757.1 - 1.3e-09 37.9 6.5 0.00011 22.0 0.2 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family Chordopox_A13L PF05961.6 EGC35757.1 - 0.00058 19.7 0.4 0.0031 17.4 0.3 2.3 1 0 0 1 1 1 1 Chordopoxvirus A13L protein DUF3430 PF11912.3 EGC35758.1 - 2.4e-13 50.4 31.1 3.3e-13 49.9 21.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC35758.1 - 0.016 15.2 6.9 0.96 9.5 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3586) MFS_1 PF07690.11 EGC35759.1 - 2.1e-48 164.8 36.0 3.4e-46 157.5 17.0 2.0 1 1 1 2 2 2 2 Major Facilitator Superfamily OATP PF03137.15 EGC35759.1 - 0.00044 18.4 12.6 0.0059 14.7 1.7 3.0 3 0 0 3 3 3 2 Organic Anion Transporter Polypeptide (OATP) family DUF1228 PF06779.9 EGC35759.1 - 2.4 8.2 6.9 2.5 8.1 0.2 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1228) MFS_3 PF05977.8 EGC35759.1 - 3 5.8 9.9 0.48 8.4 0.4 2.2 2 0 0 2 2 2 0 Transmembrane secretion effector Pepsin-I3 PF06394.8 EGC35760.1 - 0.21 11.2 4.6 0.14 11.8 1.1 2.3 2 0 0 2 2 2 0 Pepsin inhibitor-3-like repeated domain PRP1_N PF06424.7 EGC35761.1 - 8.1 6.7 13.8 1.8 8.8 6.6 2.1 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal FNIP PF05725.7 EGC35762.1 - 1.5e-47 159.2 44.8 2.5e-13 49.7 1.8 9.1 7 2 0 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 EGC35762.1 - 0.023 14.6 10.2 11 6.0 0.1 5.3 3 2 1 5 5 5 0 Protein of unknown function (DUF1769) FNIP PF05725.7 EGC35763.1 - 2.1e-96 315.6 41.3 4.9e-17 61.6 0.9 7.9 5 2 4 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC35763.1 - 5.8e-06 26.1 19.0 5.6 6.9 0.0 8.6 3 2 7 10 10 10 5 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC35763.1 - 0.0055 16.6 0.3 10 6.1 0.0 4.3 2 1 2 5 5 5 2 Phage minor tail protein EB PF01683.13 EGC35764.1 - 0.028 14.4 12.0 0.028 14.4 8.3 8.1 2 2 5 7 7 7 0 EB module DIL PF01843.14 EGC35765.1 - 1.8e-21 75.9 0.2 6.6e-21 74.1 0.1 2.1 1 0 0 1 1 1 1 DIL domain NT-C2 PF10358.4 EGC35765.1 - 1.7e-18 66.4 3.0 5e-18 64.9 2.1 1.8 1 0 0 1 1 1 1 N-terminal C2 in EEIG1 and EHBP1 proteins SlyX PF04102.7 EGC35765.1 - 0.16 12.3 52.6 0.094 13.1 2.8 8.4 7 2 1 8 8 8 0 SlyX ADIP PF11559.3 EGC35765.1 - 0.4 10.5 84.0 2.5 8.0 12.6 7.5 3 2 3 7 7 7 0 Afadin- and alpha -actinin-Binding AAA_27 PF13514.1 EGC35765.1 - 1 6.9 46.8 0.17 9.5 22.6 2.3 1 1 1 2 2 2 0 AAA domain IncA PF04156.9 EGC35765.1 - 1.2 8.7 78.3 0.035 13.7 13.1 5.3 2 2 2 4 4 4 0 IncA protein Atg14 PF10186.4 EGC35765.1 - 2.8 6.8 67.4 0.73 8.7 9.9 4.0 1 1 2 3 3 3 0 UV radiation resistance protein and autophagy-related subunit 14 AAA_13 PF13166.1 EGC35765.1 - 4.7 5.5 58.0 1.7 7.0 21.6 3.6 1 1 1 2 2 2 0 AAA domain GAS PF13851.1 EGC35765.1 - 8.1 5.5 70.5 0.019 14.1 11.6 4.7 2 1 2 4 4 4 0 Growth-arrest specific micro-tubule binding LRR_6 PF13516.1 EGC35766.1 - 9.2e-05 22.1 65.1 1.3 9.2 0.1 17.3 18 1 0 18 18 18 4 Leucine Rich repeat IstB_IS21 PF01695.12 EGC35766.1 - 0.0006 19.2 0.1 0.0015 17.9 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_28 PF13521.1 EGC35766.1 - 0.36 10.7 0.0 0.77 9.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain DUF3439 PF11921.3 EGC35766.1 - 2.6 7.8 19.6 0.39 10.4 5.0 3.4 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) WD40 PF00400.27 EGC35768.1 - 7.2e-32 108.1 20.5 2.6e-10 39.7 0.2 7.3 8 0 0 8 8 8 5 WD domain, G-beta repeat FNIP PF05725.7 EGC35769.1 - 5.3e-26 90.2 76.7 4.8e-06 26.4 1.0 12.3 10 2 2 12 12 12 8 FNIP Repeat RRM_5 PF13893.1 EGC35769.1 - 4.3e-08 32.8 2.3 3.6e-07 29.9 0.1 3.0 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC35769.1 - 5.5e-08 32.3 0.1 1.9e-07 30.6 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35769.1 - 7.9e-07 28.9 0.1 4.2e-06 26.6 0.1 2.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC35769.1 - 0.63 9.8 2.3 6.6 6.5 0.0 3.5 2 1 1 3 3 3 0 Nup53/35/40-type RNA recognition motif Lipoxygenase PF00305.14 EGC35771.1 - 1.1e-67 228.5 0.7 1.4e-67 228.2 0.5 1.0 1 0 0 1 1 1 1 Lipoxygenase HATPase_c PF02518.21 EGC35772.1 - 3.8e-27 94.1 0.1 8.2e-27 93.1 0.0 1.6 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC35772.1 - 1e-16 60.9 0.2 2.4e-16 59.7 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain HisKA PF00512.20 EGC35772.1 - 3.2e-11 43.0 0.0 7.2e-11 41.9 0.0 1.7 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_9 PF13426.1 EGC35772.1 - 8.7e-06 26.0 0.0 4.9e-05 23.6 0.0 2.5 1 0 0 1 1 1 1 PAS domain PAS_8 PF13188.1 EGC35772.1 - 1.2e-05 25.0 0.0 6.6e-05 22.6 0.0 2.2 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EGC35772.1 - 0.0037 17.0 0.0 0.15 11.8 0.0 3.0 2 0 0 2 2 2 1 PAS fold PAS_4 PF08448.5 EGC35772.1 - 0.047 13.7 0.0 0.23 11.4 0.0 2.1 1 1 0 1 1 1 0 PAS fold Pkinase PF00069.20 EGC35773.1 - 3.7e-10 39.3 0.3 1.4e-09 37.4 0.2 2.0 1 0 0 1 1 1 1 Protein kinase domain RIO1 PF01163.17 EGC35773.1 - 1.9e-09 37.1 0.1 5.8e-09 35.5 0.1 1.8 1 0 0 1 1 1 1 RIO1 family Pkinase_Tyr PF07714.12 EGC35773.1 - 9.1e-08 31.4 0.2 1.8e-07 30.4 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC35773.1 - 9.8e-08 31.2 0.0 8.3e-07 28.2 0.0 2.7 2 1 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC35773.1 - 4e-06 26.7 0.0 0.00042 20.1 0.0 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Zn_clus PF00172.13 EGC35775.1 - 3.9e-05 23.4 12.6 6.8e-05 22.6 8.8 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain Presenilin PF01080.12 EGC35776.1 - 8.9e-83 278.3 30.3 7.5e-60 202.8 8.6 2.0 1 1 1 2 2 2 2 Presenilin Synaptobrevin PF00957.16 EGC35777.1 - 1.4e-10 40.6 0.7 2.4e-10 39.8 0.5 1.4 1 0 0 1 1 1 1 Synaptobrevin Longin PF13774.1 EGC35777.1 - 5.8e-06 25.7 0.0 9.7e-06 25.0 0.0 1.4 1 0 0 1 1 1 1 Regulated-SNARE-like domain Gp-FAR-1 PF05823.7 EGC35777.1 - 0.056 13.4 0.7 0.098 12.6 0.5 1.3 1 0 0 1 1 1 0 Nematode fatty acid retinoid binding protein (Gp-FAR-1) UxaC PF02614.9 EGC35777.1 - 0.067 11.7 0.2 0.08 11.5 0.1 1.1 1 0 0 1 1 1 0 Glucuronate isomerase Use1 PF09753.4 EGC35777.1 - 0.085 12.2 0.5 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Membrane fusion protein Use1 RNA_pol_L_2 PF13656.1 EGC35778.1 - 5.4e-28 96.2 0.0 6.6e-28 95.9 0.0 1.1 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain RNA_pol_L PF01193.19 EGC35778.1 - 4.9e-10 38.3 0.0 6.3e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb3/Rpb11 dimerisation domain PARP_reg PF02877.9 EGC35778.1 - 0.073 12.7 0.0 2.3 7.8 0.0 2.1 2 0 0 2 2 2 0 Poly(ADP-ribose) polymerase, regulatory domain zf-TRM13_CCCH PF11722.3 EGC35779.1 - 0.033 13.5 2.5 0.72 9.2 0.0 2.9 2 2 0 2 2 2 0 CCCH zinc finger in TRM13 protein Meleagrin PF08189.6 EGC35779.1 - 0.06 12.8 0.1 0.12 11.8 0.1 1.5 1 0 0 1 1 1 0 Meleagrin/Cygnin family BTV_NS2 PF04514.7 EGC35779.1 - 0.33 9.7 9.1 0.6 8.9 6.3 1.3 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 eIF_4EBP PF05456.6 EGC35779.1 - 1.8 8.2 8.6 0.88 9.2 4.0 2.0 1 1 1 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) SprA-related PF12118.3 EGC35779.1 - 3.1 7.0 11.0 3.8 6.7 7.6 1.2 1 0 0 1 1 1 0 SprA-related family PBP1_TM PF14812.1 EGC35779.1 - 6.1 7.2 8.2 14 6.0 5.7 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF1032 PF06278.6 EGC35780.1 - 2.1e-48 165.1 41.9 1.6e-24 86.3 0.4 5.9 5 1 0 5 5 5 4 Protein of unknown function (DUF1032) WD40 PF00400.27 EGC35781.1 - 9.7e-45 148.9 23.2 7e-10 38.3 0.0 6.2 6 0 0 6 6 6 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC35781.1 - 0.0022 17.7 0.2 0.14 11.9 0.0 2.9 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region YmzC PF14157.1 EGC35781.1 - 0.09 12.6 0.0 25 4.8 0.0 2.9 3 0 0 3 3 3 0 YmzC-like protein GATA PF00320.22 EGC35781.1 - 0.3 10.4 1.8 1 8.7 0.1 2.3 2 0 0 2 2 2 0 GATA zinc finger CBM49 PF09478.5 EGC35782.1 - 1.2e-32 111.7 22.7 3.9e-13 49.2 2.4 3.2 3 0 0 3 3 3 3 Carbohydrate binding domain CBM49 CBM_2 PF00553.14 EGC35782.1 - 7.1e-08 32.4 14.0 0.00014 21.8 0.8 3.3 3 0 0 3 3 3 3 Cellulose binding domain CARDB PF07705.6 EGC35782.1 - 4e-06 26.7 5.1 0.37 10.8 0.3 3.3 3 0 0 3 3 3 3 CARDB DUF2080 PF09853.4 EGC35782.1 - 0.024 14.3 1.8 4.1 7.2 0.0 3.3 3 0 0 3 3 3 0 Putative transposon-encoded protein (DUF2080) BNR PF02012.15 EGC35782.1 - 1.2 9.2 3.6 51 4.3 0.0 4.0 4 0 0 4 4 4 0 BNR/Asp-box repeat DUF3617 PF12276.3 EGC35782.1 - 3.1 7.2 5.8 7.5 5.9 0.7 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3617) Ded_cyto PF06920.8 EGC35783.1 - 3.6e-49 166.4 1.8 1.2e-48 164.7 1.2 2.0 1 0 0 1 1 1 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC35783.1 - 4.9e-27 94.7 1.7 1.4e-25 90.0 0.3 2.8 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins DUF3430 PF11912.3 EGC35784.1 - 7.8e-17 61.8 23.4 8.6e-17 61.6 16.2 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF2359 PF10151.4 EGC35785.1 - 9.9e-05 21.0 7.2 0.02 13.4 0.2 3.3 3 1 1 4 4 4 3 Uncharacterised conserved protein (DUF2359) WD40 PF00400.27 EGC35786.1 - 1.2e-10 40.8 0.0 5e-09 35.6 0.0 3.3 2 0 0 2 2 2 1 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGC35786.1 - 2e-06 26.8 5.4 0.019 13.7 0.7 3.3 3 0 0 3 3 3 2 Coatomer WD associated region NARG2_C PF10505.4 EGC35787.1 - 6.8e-13 48.3 1.0 1.7e-12 46.9 0.7 1.7 1 0 0 1 1 1 1 NMDA receptor-regulated gene protein 2 C-terminus zf-CCCH PF00642.19 EGC35787.1 - 0.0032 17.1 0.5 0.0058 16.2 0.3 1.4 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) TMEM117 PF15113.1 EGC35787.1 - 7.2 5.0 5.8 3 6.3 0.1 2.7 3 0 0 3 3 3 0 TMEM117 protein family PTPLA PF04387.9 EGC35788.1 - 6.1e-56 188.3 6.2 6.1e-56 188.3 4.3 1.5 2 0 0 2 2 2 1 Protein tyrosine phosphatase-like protein, PTPLA dsDNA_bind PF01984.15 EGC35789.1 - 1.2e-25 89.6 9.8 1.2e-25 89.5 6.8 1.0 1 0 0 1 1 1 1 Double-stranded DNA-binding domain PCI PF01399.22 EGC35789.1 - 0.083 13.2 0.3 0.15 12.3 0.1 1.4 1 1 1 2 2 2 0 PCI domain FAM92 PF06730.6 EGC35789.1 - 0.2 10.9 2.7 0.21 10.9 1.8 1.1 1 0 0 1 1 1 0 FAM92 protein GHMP_kinases_N PF00288.21 EGC35790.1 - 1.9e-07 31.0 1.1 3.7e-07 30.1 0.8 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain YmaF PF12788.2 EGC35790.1 - 0.046 13.8 0.1 0.2 11.8 0.0 2.0 2 0 0 2 2 2 0 YmaF family Pkinase PF00069.20 EGC35791.1 - 4e-44 150.7 0.0 4.8e-44 150.4 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35791.1 - 3.5e-21 75.4 0.0 4.1e-21 75.2 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC35791.1 - 0.0001 21.3 0.0 0.0048 15.8 0.0 2.2 2 0 0 2 2 2 2 Kinase-like APH PF01636.18 EGC35791.1 - 0.14 11.8 0.0 2.5 7.7 0.0 2.1 1 1 0 2 2 2 0 Phosphotransferase enzyme family Lipase_3 PF01764.20 EGC35792.1 - 1.2e-17 63.8 0.0 3.1e-17 62.5 0.0 1.8 1 0 0 1 1 1 1 Lipase (class 3) ANF_receptor PF01094.23 EGC35793.1 - 7.9e-44 149.8 0.0 1.1e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Receptor family ligand binding region 7tm_3 PF00003.17 EGC35793.1 - 2.3e-36 125.3 23.0 3.7e-36 124.6 16.0 1.3 1 0 0 1 1 1 1 7 transmembrane sweet-taste receptor of 3 GCPR Peripla_BP_6 PF13458.1 EGC35793.1 - 7e-18 65.0 0.0 1.1e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Periplasmic binding protein ATP-synt_E PF05680.7 EGC35793.1 - 0.16 11.9 0.1 0.29 11.1 0.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain Cpn60_TCP1 PF00118.19 EGC35794.1 - 3.6e-141 471.1 11.4 4.1e-141 470.9 7.9 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family DUF1132 PF06575.7 EGC35794.1 - 0.0071 16.6 0.0 0.016 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1132) Dus PF01207.12 EGC35795.1 - 1.5e-72 244.0 0.0 1.8e-72 243.7 0.0 1.0 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) Oxidored_FMN PF00724.15 EGC35795.1 - 0.0068 15.4 0.0 0.012 14.6 0.0 1.5 1 1 0 1 1 1 1 NADH:flavin oxidoreductase / NADH oxidase family DUF561 PF04481.7 EGC35795.1 - 0.018 14.0 0.0 0.031 13.2 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF561) TMP-TENI PF02581.12 EGC35795.1 - 0.029 13.4 0.1 0.14 11.3 0.0 1.9 2 0 0 2 2 2 0 Thiamine monophosphate synthase/TENI His_biosynth PF00977.16 EGC35795.1 - 0.062 12.5 0.0 0.12 11.5 0.0 1.5 1 0 0 1 1 1 0 Histidine biosynthesis protein TPR_12 PF13424.1 EGC35796.1 - 3.1e-11 43.0 1.9 8.6e-05 22.4 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35796.1 - 7e-06 25.5 1.3 0.068 12.8 0.1 2.5 2 0 0 2 2 2 2 TPR repeat TPR_8 PF13181.1 EGC35796.1 - 0.0035 17.0 0.8 3.3 7.6 0.0 3.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC35796.1 - 0.015 15.1 2.8 7 6.8 0.1 4.2 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC35796.1 - 0.065 12.8 2.7 1.6 8.4 0.2 2.9 2 0 0 2 2 2 0 Tetratricopeptide repeat SSP160 PF06933.6 EGC35796.1 - 3 5.7 15.7 4.4 5.1 10.9 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGC35796.1 - 4.7 6.9 12.0 14 5.4 8.3 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TIM21 PF08294.6 EGC35797.1 - 0.00022 20.9 0.0 0.00042 20.0 0.0 1.5 1 0 0 1 1 1 1 TIM21 Mad3_BUB1_I PF08311.7 EGC35797.1 - 0.035 13.8 2.4 22 4.8 0.0 3.3 2 1 1 3 3 3 0 Mad3/BUB1 homology region 1 Leukemia_assc_2 PF15197.1 EGC35797.1 - 0.53 9.9 4.8 0.93 9.2 2.0 2.3 2 0 0 2 2 2 0 Leukemia-associated protein 2 DUF1206 PF06724.6 EGC35798.1 - 1.4e-14 53.5 15.9 1e-05 25.2 0.2 3.3 3 0 0 3 3 3 3 Domain of Unknown Function (DUF1206) DUF3439 PF11921.3 EGC35798.1 - 5.4 6.7 10.8 40 3.9 7.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Myb_DNA-binding PF00249.26 EGC35799.1 - 2.2e-27 94.8 14.1 5.7e-11 42.2 0.9 3.3 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC35799.1 - 2.2e-25 88.4 14.9 2.5e-12 46.7 0.9 3.4 2 1 1 3 3 3 3 Myb-like DNA-binding domain SLIDE PF09111.5 EGC35799.1 - 0.023 14.4 4.9 0.11 12.2 0.2 3.3 1 1 1 3 3 3 0 SLIDE XH PF03469.9 EGC35799.1 - 0.69 9.5 7.1 0.87 9.2 0.2 2.9 1 1 2 3 3 3 0 XH domain TMEM154 PF15102.1 EGC35800.1 - 0.026 14.2 0.2 0.026 14.2 0.2 1.7 2 0 0 2 2 2 0 TMEM154 protein family MtrB PF05440.7 EGC35801.1 - 0.059 13.4 0.0 0.12 12.4 0.0 1.5 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase subunit B Rhodopsin_N PF10413.4 EGC35803.1 - 0.02 14.5 0.2 1.8 8.2 0.1 2.3 2 0 0 2 2 2 0 Amino terminal of the G-protein receptor rhodopsin DUF4380 PF14315.1 EGC35805.1 - 7.7e-61 205.6 0.1 9.9e-61 205.3 0.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4380) Myotub-related PF06602.9 EGC35806.1 - 1.3e-113 379.4 0.0 3.2e-113 378.0 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGC35806.1 - 0.0019 18.4 0.1 0.16 12.2 0.0 2.8 2 0 0 2 2 2 1 Tyrosine phosphatase family Cytomega_UL84 PF06284.6 EGC35806.1 - 1.2 7.4 5.3 0.14 10.5 0.5 1.6 2 0 0 2 2 2 0 Cytomegalovirus UL84 protein POX PF07526.6 EGC35806.1 - 5.4 7.2 13.2 13 5.9 4.0 2.7 2 0 0 2 2 2 0 Associated with HOX IMPDH PF00478.20 EGC35807.1 - 3.6e-136 453.6 2.9 4.3e-136 453.4 2.0 1.0 1 0 0 1 1 1 1 IMP dehydrogenase / GMP reductase domain CBS PF00571.23 EGC35807.1 - 3e-15 55.7 0.1 3.4e-06 26.7 0.0 2.5 2 0 0 2 2 2 2 CBS domain NMO PF03060.10 EGC35807.1 - 6.9e-10 38.5 1.0 1.4e-06 27.7 0.2 2.4 2 1 0 2 2 2 2 Nitronate monooxygenase FMN_dh PF01070.13 EGC35807.1 - 1.6e-06 27.2 0.2 1.2e-05 24.3 0.3 2.1 2 1 0 2 2 2 1 FMN-dependent dehydrogenase His_biosynth PF00977.16 EGC35807.1 - 0.00048 19.4 0.9 0.003 16.8 0.6 2.2 1 1 0 1 1 1 1 Histidine biosynthesis protein ThiG PF05690.9 EGC35807.1 - 0.00077 18.6 0.8 0.0051 15.9 0.1 2.1 1 1 1 2 2 2 1 Thiazole biosynthesis protein ThiG B12-binding PF02310.14 EGC35807.1 - 0.019 14.8 0.0 0.036 13.9 0.0 1.4 1 0 0 1 1 1 0 B12 binding domain DHO_dh PF01180.16 EGC35807.1 - 0.038 12.9 1.2 0.07 12.0 0.2 1.8 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase DUF561 PF04481.7 EGC35807.1 - 0.13 11.2 1.4 0.4 9.5 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF561) Pkinase PF00069.20 EGC35808.1 - 6.1e-55 186.1 0.1 1.6e-54 184.8 0.1 1.8 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35808.1 - 1.9e-54 184.5 0.1 3.3e-54 183.7 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RA PF00788.18 EGC35808.1 - 8.5e-07 29.3 0.1 0.0076 16.7 0.0 3.1 2 0 0 2 2 2 2 Ras association (RalGDS/AF-6) domain WD40 PF00400.27 EGC35809.1 - 6.1e-39 130.5 3.0 3.2e-10 39.4 0.0 6.4 6 0 0 6 6 6 5 WD domain, G-beta repeat Sof1 PF04158.9 EGC35809.1 - 1.2e-22 79.6 6.8 1.2e-22 79.6 4.7 1.6 2 0 0 2 2 2 1 Sof1-like domain Coatomer_WDAD PF04053.9 EGC35809.1 - 0.021 13.6 0.2 0.096 11.4 0.1 2.0 1 1 1 2 2 2 0 Coatomer WD associated region Pkinase PF00069.20 EGC35810.1 - 3e-55 187.1 0.2 3e-55 187.1 0.1 2.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35810.1 - 1.6e-20 73.2 0.0 1.6e-20 73.2 0.0 2.0 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGC35810.1 - 0.085 12.5 0.0 0.085 12.5 0.0 1.9 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF501 PF04417.7 EGC35810.1 - 1.8 8.4 7.4 3.6 7.4 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF501) SGL PF08450.7 EGC35811.1 - 9.6e-77 257.6 0.2 1.1e-76 257.4 0.1 1.0 1 0 0 1 1 1 1 SMP-30/Gluconolaconase/LRE-like region Reg_prop PF07494.6 EGC35811.1 - 0.0033 17.2 2.9 2.1 8.6 0.0 3.8 3 0 0 3 3 3 2 Two component regulator propeller VCBS PF13517.1 EGC35811.1 - 0.068 13.5 0.5 0.27 11.6 0.4 2.0 1 0 0 1 1 1 0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella Tmemb_170 PF10190.4 EGC35812.1 - 4.4e-06 26.6 7.2 5.3e-06 26.4 5.0 1.0 1 0 0 1 1 1 1 Putative transmembrane protein 170 SieB PF14163.1 EGC35812.1 - 0.024 14.2 1.8 0.024 14.2 1.2 2.0 2 0 0 2 2 2 0 Superinfection exclusion protein B zf-C2H2_jaz PF12171.3 EGC35813.1 - 1.8e-10 40.6 16.8 2e-07 30.9 1.3 2.8 3 0 0 3 3 3 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC35813.1 - 1.5e-08 34.5 6.0 2.5e-08 33.8 0.2 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGC35813.1 - 3.3e-06 27.1 13.1 0.00019 21.4 5.0 3.1 1 1 1 2 2 2 1 C2H2 type zinc-finger (2 copies) AKAP95 PF04988.7 EGC35813.1 - 0.0019 18.0 9.1 0.12 12.1 1.3 2.6 2 1 0 2 2 2 2 A-kinase anchoring protein 95 (AKAP95) zf-C2H2_6 PF13912.1 EGC35813.1 - 0.0049 16.7 4.0 0.38 10.7 0.1 2.7 2 0 0 2 2 2 1 C2H2-type zinc finger zf-trcl PF13451.1 EGC35813.1 - 0.041 13.5 1.1 1.3 8.6 0.1 2.4 2 0 0 2 2 2 0 Probable zinc-binding domain zf-H2C2_2 PF13465.1 EGC35813.1 - 0.062 13.6 0.5 0.062 13.6 0.4 3.5 4 0 0 4 4 4 0 Zinc-finger double domain zf-BED PF02892.10 EGC35813.1 - 0.092 12.5 0.3 0.092 12.5 0.2 2.7 3 0 0 3 3 3 0 BED zinc finger zf-C2H2 PF00096.21 EGC35813.1 - 0.11 12.8 0.4 0.11 12.8 0.3 2.8 3 0 0 3 3 2 0 Zinc finger, C2H2 type C1_4 PF07975.7 EGC35813.1 - 0.14 12.1 5.9 3 7.9 0.3 3.2 3 0 0 3 3 3 0 TFIIH C1-like domain zf-DBF PF07535.7 EGC35813.1 - 0.23 11.1 7.4 0.41 10.3 0.1 2.4 2 0 0 2 2 2 0 DBF zinc finger zf-LYAR PF08790.6 EGC35813.1 - 0.48 10.1 5.5 1 9.0 1.0 2.5 2 0 0 2 2 2 0 LYAR-type C2HC zinc finger LIM PF00412.17 EGC35813.1 - 0.99 9.5 7.1 1.3 9.1 0.1 2.9 3 0 0 3 3 3 0 LIM domain Asp-B-Hydro_N PF05279.6 EGC35813.1 - 1.4 8.7 7.7 1.7 8.4 5.4 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Yippee-Mis18 PF03226.9 EGC35813.1 - 1.5 8.9 4.6 0.27 11.3 0.3 1.9 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Elf1 PF05129.8 EGC35813.1 - 1.6 8.5 13.5 0.33 10.6 1.3 3.3 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like XhlA PF10779.4 EGC35813.1 - 4 7.4 6.3 1 9.3 0.8 2.2 2 0 0 2 2 2 0 Haemolysin XhlA Daxx PF03344.10 EGC35814.1 - 0.00019 20.1 9.4 0.00026 19.6 6.5 1.2 1 0 0 1 1 1 1 Daxx Family Nop14 PF04147.7 EGC35814.1 - 0.00094 17.2 13.4 0.00094 17.2 9.3 1.8 3 0 0 3 3 3 1 Nop14-like family YL1 PF05764.8 EGC35814.1 - 0.0041 16.7 13.2 0.0074 15.9 9.1 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Mpp10 PF04006.7 EGC35814.1 - 0.005 15.2 18.7 0.011 14.1 13.0 1.4 1 0 0 1 1 1 1 Mpp10 protein CDC45 PF02724.9 EGC35814.1 - 0.078 11.0 9.3 0.12 10.3 6.4 1.3 1 0 0 1 1 1 0 CDC45-like protein TRAP_alpha PF03896.11 EGC35814.1 - 0.14 11.1 8.9 0.24 10.3 6.2 1.4 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit TrbI PF03743.9 EGC35814.1 - 1 8.8 3.5 3.1 7.2 0.1 2.4 2 0 0 2 2 2 0 Bacterial conjugation TrbI-like protein SDA1 PF05285.7 EGC35814.1 - 4.5 6.4 20.6 8.7 5.5 14.3 1.4 1 0 0 1 1 1 0 SDA1 BUD22 PF09073.5 EGC35814.1 - 5.1 6.0 14.4 0.84 8.6 7.0 1.9 2 0 0 2 2 2 0 BUD22 FlaC_arch PF05377.6 EGC35815.1 - 0.026 14.4 0.2 0.088 12.7 0.1 1.9 1 0 0 1 1 1 0 Flagella accessory protein C (FlaC) Fumble PF03630.9 EGC35817.1 - 2.7e-123 411.1 1.3 2.7e-123 411.1 0.9 1.9 2 1 0 2 2 2 1 Fumble LRR_4 PF12799.2 EGC35818.1 - 6.3e-32 108.6 47.2 4.7e-10 38.8 2.1 7.0 4 1 5 9 9 9 7 Leucine Rich repeats (2 copies) C2 PF00168.25 EGC35818.1 - 1.1e-22 79.6 0.0 2.1e-22 78.7 0.0 1.5 1 0 0 1 1 1 1 C2 domain LRR_8 PF13855.1 EGC35818.1 - 9.3e-17 60.5 16.0 3e-08 33.2 0.3 4.8 2 1 5 7 7 7 5 Leucine rich repeat LRR_1 PF00560.28 EGC35818.1 - 3e-16 56.9 22.2 0.0037 17.0 0.1 9.7 9 0 0 9 9 9 5 Leucine Rich Repeat LRR_7 PF13504.1 EGC35818.1 - 3.8e-12 44.2 14.3 0.35 11.2 0.2 8.7 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 EGC35818.1 - 0.0046 16.8 21.8 1.8 8.8 0.2 8.3 9 0 0 9 9 9 2 Leucine Rich repeat LRR_9 PF14580.1 EGC35818.1 - 0.039 13.5 6.7 1.6 8.2 0.2 3.3 1 1 3 4 4 4 0 Leucine-rich repeat CLTH PF10607.4 EGC35819.1 - 1.8e-35 121.7 5.2 1.8e-35 121.7 3.6 2.3 2 1 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain zf-RING_UBOX PF13445.1 EGC35819.1 - 0.0026 17.4 0.0 0.019 14.6 0.0 2.6 2 0 0 2 2 2 1 RING-type zinc-finger CAMP_factor PF07373.6 EGC35819.1 - 0.0035 16.8 2.2 0.0035 16.8 1.5 2.0 2 0 0 2 2 2 1 CAMP factor (Cfa) U-box PF04564.10 EGC35819.1 - 0.01 15.7 0.6 0.039 13.9 0.0 2.3 3 0 0 3 3 3 0 U-box domain LisH PF08513.6 EGC35819.1 - 0.03 14.0 0.1 0.066 13.0 0.0 1.6 1 0 0 1 1 1 0 LisH DUF3610 PF12272.3 EGC35819.1 - 0.25 11.0 5.6 0.07 12.7 1.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3610) G10 PF01125.12 EGC35819.1 - 0.29 10.6 3.3 0.72 9.4 2.3 1.7 1 0 0 1 1 1 0 G10 protein Occludin_ELL PF07303.8 EGC35819.1 - 4.4 8.0 12.4 0.35 11.6 4.4 2.3 2 1 1 3 3 3 0 Occludin homology domain DUF948 PF06103.6 EGC35819.1 - 4.4 7.2 8.2 0.66 9.8 1.9 2.4 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Cytochrom_B562 PF07361.6 EGC35819.1 - 6 7.3 8.8 10 6.5 3.2 2.4 2 0 0 2 2 2 0 Cytochrome b562 Oxysterol_BP PF01237.13 EGC35821.1 - 2.3e-106 355.2 0.3 2.9e-106 354.9 0.2 1.0 1 0 0 1 1 1 1 Oxysterol-binding protein LMBR1 PF04791.11 EGC35822.1 - 3.7e-41 141.2 24.0 1.1e-23 83.6 3.0 2.1 2 0 0 2 2 2 2 LMBR1-like membrane protein ATP1G1_PLM_MAT8 PF02038.11 EGC35822.1 - 0.018 14.0 0.1 0.099 11.6 0.1 2.3 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family Use1 PF09753.4 EGC35822.1 - 0.55 9.6 2.1 5 6.4 1.9 2.1 2 0 0 2 2 2 0 Membrane fusion protein Use1 NPCC PF08058.6 EGC35822.1 - 0.69 9.7 2.8 2.1 8.2 1.9 1.9 1 0 0 1 1 1 0 Nuclear pore complex component ABC_membrane PF00664.18 EGC35823.1 - 4.1e-61 206.8 39.1 2.6e-31 109.0 14.9 2.4 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC35823.1 - 1.2e-47 161.6 7.0 1.7e-28 99.6 0.1 4.7 4 0 0 4 4 4 3 ABC transporter MMR_HSR1 PF01926.18 EGC35823.1 - 7.5e-27 93.5 1.2 3.5e-21 75.3 0.0 4.0 3 0 0 3 3 3 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC35823.1 - 1.5e-10 40.5 0.1 9.2e-10 38.0 0.0 2.3 2 0 0 2 2 2 1 Ferrous iron transport protein B SMC_N PF02463.14 EGC35823.1 - 1.3e-09 37.6 16.4 0.014 14.6 0.3 5.0 3 2 2 5 5 4 4 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC35823.1 - 1.8e-09 36.9 1.6 0.032 13.7 0.1 3.6 3 0 0 3 3 3 3 P-loop containing region of AAA domain DUF258 PF03193.11 EGC35823.1 - 2.3e-08 33.3 2.9 0.002 17.3 0.0 3.7 3 1 0 3 3 3 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC35823.1 - 1e-07 31.5 2.3 0.0012 18.3 0.2 4.2 4 0 0 4 4 4 2 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGC35823.1 - 1.8e-06 27.8 17.8 0.016 15.0 0.0 5.5 6 2 1 7 7 6 3 Dynamin family Miro PF08477.8 EGC35823.1 - 1.9e-06 28.3 8.1 0.15 12.5 0.1 4.7 4 0 0 4 4 3 2 Miro-like protein AAA_18 PF13238.1 EGC35823.1 - 4e-06 27.1 0.9 1.6 9.0 0.0 4.5 3 0 0 3 3 3 2 AAA domain FtsK_SpoIIIE PF01580.13 EGC35823.1 - 2.8e-05 23.7 2.4 0.022 14.2 0.0 3.2 3 0 0 3 3 3 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EGC35823.1 - 3.8e-05 23.7 0.5 0.49 10.3 0.2 3.5 3 0 0 3 3 3 1 AAA ATPase domain AAA_17 PF13207.1 EGC35823.1 - 0.0001 23.1 2.4 5.1 7.9 0.3 4.0 3 1 0 3 3 3 1 AAA domain MobB PF03205.9 EGC35823.1 - 0.0001 22.0 2.4 1.2 8.8 0.0 3.9 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B T2SE PF00437.15 EGC35823.1 - 0.0004 19.3 0.3 0.21 10.4 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EGC35823.1 - 0.0005 19.5 1.8 2.3 7.5 0.6 3.3 3 0 0 3 3 3 1 AAA-like domain PduV-EutP PF10662.4 EGC35823.1 - 0.0014 18.1 8.0 1.3 8.5 0.0 4.3 5 0 0 5 5 5 2 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGC35823.1 - 0.0018 18.3 6.0 1.6 8.8 0.4 4.3 3 2 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EGC35823.1 - 0.003 17.6 0.2 12 6.0 0.0 4.2 3 0 0 3 3 3 0 RNA helicase cobW PF02492.14 EGC35823.1 - 0.006 16.0 3.2 0.9 8.9 0.0 3.6 3 0 0 3 3 3 1 CobW/HypB/UreG, nucleotide-binding domain Sigma54_activat PF00158.21 EGC35823.1 - 0.0081 15.6 0.1 0.22 11.0 0.0 2.6 3 0 0 3 3 2 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGC35823.1 - 0.012 15.0 1.2 0.43 9.9 0.0 3.0 3 0 0 3 3 3 0 AAA domain AAA_28 PF13521.1 EGC35823.1 - 1.6 8.6 4.0 11 5.9 0.0 3.2 3 0 0 3 3 3 0 AAA domain Aldedh PF00171.17 EGC35824.1 - 1.8e-126 422.1 0.0 2.1e-126 421.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family WD40 PF00400.27 EGC35825.1 - 1.7e-22 78.3 10.7 4e-09 35.9 0.1 5.9 6 0 0 6 6 6 4 WD domain, G-beta repeat DUF3337 PF11816.3 EGC35825.1 - 2.9e-20 72.9 0.9 2.9e-20 72.9 0.6 3.6 3 2 0 3 3 3 1 Domain of unknown function (DUF3337) Ribosomal_S8e PF01201.17 EGC35826.1 - 2.7e-37 127.8 8.1 1.8e-36 125.2 5.6 2.2 1 1 0 1 1 1 1 Ribosomal protein S8e HPD PF05044.7 EGC35826.1 - 0.066 12.8 2.4 0.22 11.1 0.3 2.1 1 1 0 2 2 2 0 Homeo-prospero domain BolA PF01722.13 EGC35827.1 - 2.2e-14 53.1 0.0 2.5e-14 52.9 0.0 1.1 1 0 0 1 1 1 1 BolA-like protein FNIP PF05725.7 EGC35829.1 - 1.7e-05 24.6 33.2 0.004 17.0 3.3 6.2 5 2 1 6 6 6 3 FNIP Repeat Peptidase_S28 PF05577.7 EGC35830.1 - 5.2e-97 325.1 7.5 6e-97 324.9 5.2 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_6 PF12697.2 EGC35830.1 - 5.4e-05 23.1 0.0 8.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC35830.1 - 0.022 14.3 0.0 0.042 13.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC35830.1 - 0.046 13.4 0.0 0.071 12.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Methyltransf_23 PF13489.1 EGC35830.1 - 0.069 12.8 0.1 0.25 11.0 0.0 2.0 2 1 0 2 2 2 0 Methyltransferase domain Orthopox_F7 PF05813.7 EGC35830.1 - 0.12 12.2 0.0 1.1 9.2 0.0 2.4 3 0 0 3 3 3 0 Orthopoxvirus F7 protein Glyco_transf_20 PF00982.16 EGC35831.1 - 1.5e-111 373.1 0.0 2.1e-111 372.7 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGC35831.1 - 5.1e-39 133.5 0.0 7.9e-39 132.9 0.0 1.3 1 0 0 1 1 1 1 Trehalose-phosphatase NAD_kinase PF01513.16 EGC35831.1 - 0.07 11.8 0.0 0.13 10.9 0.0 1.4 1 0 0 1 1 1 0 ATP-NAD kinase Toprim PF01751.17 EGC35831.1 - 0.077 12.9 0.5 0.3 11.0 0.0 2.3 2 0 0 2 2 2 0 Toprim domain Homeobox PF00046.24 EGC35832.1 - 0.00018 21.0 0.1 0.0033 16.9 0.0 2.4 2 0 0 2 2 2 1 Homeobox domain GRAM PF02893.15 EGC35833.1 - 0.093 12.2 0.2 0.2 11.2 0.2 1.6 1 0 0 1 1 1 0 GRAM domain C1_3 PF07649.7 EGC35834.1 - 0.23 11.5 2.4 0.45 10.5 0.1 2.1 2 0 0 2 2 2 0 C1-like domain zf-UDP PF14569.1 EGC35834.1 - 4.7 7.0 8.1 13 5.6 0.2 2.3 2 1 0 2 2 2 0 Zinc-binding RING-finger Zn-ribbon_8 PF09723.5 EGC35834.1 - 7.4 6.6 6.8 2.7 8.0 1.0 2.3 2 0 0 2 2 2 0 Zinc ribbon domain Zn_Tnp_IS1 PF03811.8 EGC35834.1 - 9 5.8 12.5 1.4 8.4 3.9 2.2 2 0 0 2 2 2 0 InsA N-terminal domain GATA PF00320.22 EGC35835.1 - 3.2e-08 32.7 6.9 1.1e-07 31.1 4.8 1.9 1 1 0 1 1 1 1 GATA zinc finger DUF4508 PF14969.1 EGC35835.1 - 0.046 13.7 0.2 0.055 13.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) AT_hook PF02178.14 EGC35835.1 - 0.055 13.1 7.4 0.11 12.2 5.1 1.5 1 0 0 1 1 1 0 AT hook motif DUF3439 PF11921.3 EGC35836.1 - 1.2 8.9 6.6 0.15 11.7 1.5 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF3439) HMG_box PF00505.14 EGC35839.1 - 1.4e-18 66.8 3.8 2.9e-18 65.8 2.6 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGC35839.1 - 1.3e-14 54.2 5.2 3e-14 53.1 3.6 1.7 1 0 0 1 1 1 1 HMG-box domain HMG_box_5 PF14887.1 EGC35839.1 - 0.024 14.4 1.9 0.024 14.4 1.3 2.1 2 0 0 2 2 2 0 HMG (high mobility group) box 5 tRNA-synt_2c PF01411.14 EGC35840.1 - 7.2e-72 242.4 1.4 4.2e-63 213.4 0.3 2.0 1 1 1 2 2 2 2 tRNA synthetases class II (A) GATA PF00320.22 EGC35842.1 - 0.066 12.5 4.5 0.14 11.5 3.1 1.6 1 0 0 1 1 1 0 GATA zinc finger DUF1077 PF06417.7 EGC35842.1 - 0.072 12.4 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) ArfGap PF01412.13 EGC35842.1 - 0.091 12.5 0.9 0.15 11.8 0.6 1.3 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf Zn-ribbon_8 PF09723.5 EGC35842.1 - 0.29 11.1 1.7 2.3 8.2 1.4 2.1 1 1 1 2 2 2 0 Zinc ribbon domain LAGLIDADG_1 PF00961.14 EGC35843.1 - 0.097 13.2 3.3 0.13 12.8 2.3 1.2 1 0 0 1 1 1 0 LAGLIDADG endonuclease DUF4264 PF14084.1 EGC35844.1 - 0.0092 15.3 0.0 0.052 12.9 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF4264) FNIP PF05725.7 EGC35845.1 - 1.6e-35 120.7 60.3 4.7e-11 42.4 1.9 9.9 7 2 5 12 12 12 8 FNIP Repeat Pkinase_Tyr PF07714.12 EGC35846.1 - 3.8e-19 68.7 0.0 1.6e-15 56.9 0.0 3.0 2 1 0 2 2 2 2 Protein tyrosine kinase Pkinase PF00069.20 EGC35846.1 - 3.5e-18 65.7 0.1 3.8e-16 59.0 0.1 2.5 1 1 0 1 1 1 1 Protein kinase domain APH PF01636.18 EGC35846.1 - 3.4e-05 23.6 0.0 4.6e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGC35846.1 - 0.0016 17.5 0.0 0.0021 17.0 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase P22_CoatProtein PF11651.3 EGC35846.1 - 0.011 14.3 0.0 0.19 10.3 0.0 2.0 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 RNase_T PF00929.19 EGC35850.1 - 0.0012 19.1 0.0 0.0032 17.7 0.0 1.7 1 0 0 1 1 1 1 Exonuclease MAM33 PF02330.11 EGC35850.1 - 0.062 13.0 2.2 0.82 9.4 0.1 2.8 3 0 0 3 3 3 0 Mitochondrial glycoprotein RNase_T PF00929.19 EGC35851.1 - 1.8e-14 54.3 0.2 7.1e-13 49.1 0.0 2.4 2 0 0 2 2 2 1 Exonuclease DUF3450 PF11932.3 EGC35851.1 - 0.0059 15.9 14.3 0.0094 15.2 9.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3450) CENP-F_leu_zip PF10473.4 EGC35851.1 - 0.016 15.0 18.7 0.037 13.8 13.0 1.6 1 0 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 YjcQ PF09639.5 EGC35851.1 - 0.019 15.0 0.2 0.019 15.0 0.1 2.7 3 1 0 3 3 3 0 YjcQ protein DUF2630 PF10944.3 EGC35851.1 - 0.26 11.3 8.6 0.1 12.7 3.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2630) GATA PF00320.22 EGC35853.1 - 0.0018 17.6 8.5 0.0029 16.9 5.9 1.3 1 0 0 1 1 1 1 GATA zinc finger eIF2A PF08662.6 EGC35853.1 - 0.1 12.2 0.0 0.13 11.9 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor eIF2A zf-C2H2_6 PF13912.1 EGC35853.1 - 0.19 11.6 0.1 0.19 11.6 0.1 2.4 3 0 0 3 3 3 0 C2H2-type zinc finger Eapp_C PF10238.4 EGC35854.1 - 3.2e-44 150.1 22.1 2e-43 147.5 15.3 1.8 1 1 0 1 1 1 1 E2F-associated phosphoprotein Yippee-Mis18 PF03226.9 EGC35854.1 - 0.004 17.1 7.7 0.0064 16.5 5.3 1.3 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MRP-S31 PF15433.1 EGC35854.1 - 0.026 13.9 0.0 0.035 13.5 0.0 1.1 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 CENP-B_dimeris PF09026.5 EGC35854.1 - 0.44 10.8 5.2 0.2 11.8 0.6 2.2 2 0 0 2 2 2 0 Centromere protein B dimerisation domain PBP1_TM PF14812.1 EGC35854.1 - 1.1 9.6 6.8 4.5 7.6 0.8 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mak16 PF04874.9 EGC35854.1 - 1.3 9.1 7.9 0.096 12.7 1.2 1.9 2 0 0 2 2 2 0 Mak16 protein C-terminal region CAP PF00188.21 EGC35855.1 - 2.6e-15 56.9 0.1 5.1e-15 56.0 0.1 1.6 1 0 0 1 1 1 1 Cysteine-rich secretory protein family Neisseria_TspB PF05616.8 EGC35855.1 - 2.3 6.5 12.2 3.1 6.0 8.4 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Trypan_PARP PF05887.6 EGC35855.1 - 3.1 7.6 16.1 5.1 6.9 11.1 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Pkinase_Tyr PF07714.12 EGC35856.1 - 0.00047 19.3 0.3 0.00058 19.0 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35856.1 - 0.00086 18.5 1.5 0.0011 18.1 1.0 1.1 1 0 0 1 1 1 1 Protein kinase domain DUF244 PF03112.9 EGC35856.1 - 0.073 12.6 8.0 0.051 13.1 4.4 1.5 1 1 0 1 1 1 0 Uncharacterized protein family (ORF7) DUF UvdE PF03851.9 EGC35856.1 - 0.12 11.3 0.2 0.15 11.0 0.2 1.1 1 0 0 1 1 1 0 UV-endonuclease UvdE PYST-C1 PF09690.5 EGC35856.1 - 3.6 7.2 11.6 1.1 8.9 4.7 2.2 1 1 1 2 2 2 0 Plasmodium yoelii subtelomeric region (PYST-C1) Pkinase PF00069.20 EGC35857.1 - 0.00043 19.5 0.0 0.00066 18.9 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain FNIP PF05725.7 EGC35857.1 - 0.011 15.7 0.2 0.011 15.7 0.1 4.0 3 1 1 4 4 4 0 FNIP Repeat E1-E2_ATPase PF00122.15 EGC35859.1 - 2e-60 203.7 3.0 4.8e-60 202.4 2.1 1.7 1 0 0 1 1 1 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC35859.1 - 5.6e-39 133.5 3.4 5.6e-39 133.5 2.4 2.1 2 0 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC35859.1 - 9.5e-33 114.4 0.0 5.6e-32 111.9 0.0 2.3 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC35859.1 - 5.9e-25 87.0 0.0 1.4e-24 85.8 0.0 1.7 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGC35859.1 - 1.5e-16 61.1 0.0 3.6e-16 59.8 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC35859.1 - 1.5e-15 56.4 0.0 3.2e-15 55.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGC35859.1 - 0.00097 18.7 0.3 0.0056 16.2 0.2 4.8 5 0 0 5 5 5 2 haloacid dehalogenase-like hydrolase DUF202 PF02656.10 EGC35859.1 - 0.56 10.4 3.5 1.6 9.0 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF202) ChAPs PF09295.5 EGC35860.1 - 4.9e-22 78.2 0.0 1.3e-16 60.3 0.0 2.9 1 1 1 2 2 2 2 ChAPs (Chs5p-Arf1p-binding proteins) TPR_14 PF13428.1 EGC35860.1 - 3.8e-07 30.1 1.2 0.06 14.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC35860.1 - 5.9e-07 29.9 0.2 0.11 13.2 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC35860.1 - 3.8e-06 26.4 2.2 0.18 11.8 0.0 3.5 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35860.1 - 0.00062 19.3 0.1 1.7 8.3 0.1 3.4 3 0 0 3 3 3 1 TPR repeat TPR_19 PF14559.1 EGC35860.1 - 0.00089 19.5 0.2 0.47 10.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC35860.1 - 0.017 15.2 0.4 2.5 8.5 0.0 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC35860.1 - 0.044 13.7 0.3 19 5.2 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC35860.1 - 0.045 13.3 0.9 25 4.6 0.0 3.5 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC35860.1 - 0.051 14.0 2.2 1.6 9.3 0.1 3.0 3 0 0 3 3 2 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC35860.1 - 0.12 12.3 2.2 2.8 8.0 0.4 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGC35860.1 - 0.13 12.7 0.0 13 6.5 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC35860.1 - 0.19 11.5 1.5 47 4.0 0.0 4.0 4 0 0 4 4 4 0 Tetratricopeptide repeat Peptidase_M48 PF01435.13 EGC35861.1 - 3.9e-16 59.2 0.0 6.6e-16 58.5 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M48 Peptidase_M56 PF05569.6 EGC35861.1 - 7.8e-05 21.7 1.9 0.00018 20.6 0.9 1.9 1 1 1 2 2 2 1 BlaR1 peptidase M56 DUF2268 PF10026.4 EGC35861.1 - 0.024 14.0 0.3 0.037 13.4 0.2 1.3 1 0 0 1 1 1 0 Predicted Zn-dependent protease (DUF2268) PG_binding_1 PF01471.13 EGC35862.1 - 1.5e-07 31.2 0.0 3e-07 30.3 0.0 1.5 1 0 0 1 1 1 1 Putative peptidoglycan binding domain Ras PF00071.17 EGC35863.1 - 3.9e-61 205.1 0.2 4.6e-61 204.9 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35863.1 - 7.9e-18 65.0 0.0 1.1e-17 64.5 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC35863.1 - 6.8e-15 54.7 0.0 8.5e-15 54.4 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC35863.1 - 2e-05 23.8 0.1 2.2e-05 23.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC35863.1 - 0.0017 18.2 0.0 0.0022 17.9 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC35863.1 - 0.0029 17.0 0.2 0.011 15.1 0.0 1.9 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGC35863.1 - 0.0079 15.4 0.1 0.042 13.1 0.0 1.9 1 1 0 1 1 1 1 Ferrous iron transport protein B SRPRB PF09439.5 EGC35863.1 - 0.012 14.8 0.1 0.016 14.4 0.1 1.3 1 1 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGC35863.1 - 0.039 14.1 0.0 0.074 13.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGC35863.1 - 0.065 12.4 0.0 0.22 10.7 0.0 1.7 1 1 0 2 2 2 0 Protein of unknown function, DUF258 DUF503 PF04456.7 EGC35863.1 - 0.094 12.3 0.1 0.15 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF503) Septin PF00735.13 EGC35863.1 - 0.095 11.7 0.2 0.23 10.4 0.0 1.7 2 0 0 2 2 2 0 Septin AAA_29 PF13555.1 EGC35863.1 - 0.1 12.1 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC35863.1 - 0.1 12.5 0.0 0.19 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain PIP5K PF01504.13 EGC35864.1 - 2e-61 207.3 7.2 4.6e-61 206.1 5.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase WD40 PF00400.27 EGC35865.1 - 1.4e-53 176.9 22.3 3e-10 39.5 0.1 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat F-box-like PF12937.2 EGC35865.1 - 3.2e-12 45.9 1.0 6e-12 45.1 0.7 1.5 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGC35865.1 - 2.4e-07 29.2 5.4 0.17 10.0 0.1 4.5 1 1 3 4 4 4 4 Nucleoporin Nup120/160 F-box PF00646.28 EGC35865.1 - 1.2e-06 28.0 2.6 3.4e-06 26.5 1.8 1.8 1 1 0 1 1 1 1 F-box domain HCaRG PF07258.9 EGC35866.1 - 7.4e-14 51.6 0.2 7.7e-14 51.6 0.1 1.0 1 0 0 1 1 1 1 HCaRG protein DHC_N1 PF08385.7 EGC35866.1 - 0.0032 15.9 0.1 0.0033 15.8 0.1 1.0 1 0 0 1 1 1 1 Dynein heavy chain, N-terminal region 1 DUF4210 PF13915.1 EGC35866.1 - 0.085 13.1 0.0 0.11 12.7 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4210) Nop52 PF05997.7 EGC35867.1 - 2e-41 141.7 6.3 6.2e-41 140.2 4.3 1.8 1 1 0 1 1 1 1 Nucleolar protein,Nop52 Suf PF05843.9 EGC35867.1 - 0.016 14.9 11.3 0.032 13.9 7.8 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Nop14 PF04147.7 EGC35867.1 - 0.13 10.1 36.7 0.33 8.8 25.5 1.7 1 0 0 1 1 1 0 Nop14-like family BUD22 PF09073.5 EGC35867.1 - 0.8 8.6 34.9 1.3 8.0 24.2 1.3 1 0 0 1 1 1 0 BUD22 Herpes_UL14 PF03580.9 EGC35867.1 - 0.9 9.3 8.8 2 8.1 6.1 1.6 1 0 0 1 1 1 0 Herpesvirus UL14-like protein CENP-T PF15511.1 EGC35867.1 - 1.4 8.0 27.2 2 7.5 18.9 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TIG PF01833.19 EGC35868.1 - 2.1e-05 24.4 1.4 2.1e-05 24.4 0.9 5.6 6 0 0 6 6 6 3 IPT/TIG domain LRR_1 PF00560.28 EGC35868.1 - 1.5 9.1 5.5 1.1e+02 3.4 1.7 4.1 2 1 0 2 2 2 0 Leucine Rich Repeat NUDIX PF00293.23 EGC35869.1 - 0.0047 16.5 0.8 0.11 12.1 0.5 2.3 1 1 0 1 1 1 1 NUDIX domain PTPS PF01242.14 EGC35870.1 - 2.1e-34 117.8 0.3 2.3e-34 117.7 0.2 1.0 1 0 0 1 1 1 1 6-pyruvoyl tetrahydropterin synthase DDE_3 PF13358.1 EGC35871.1 - 0.0029 17.3 0.0 0.0031 17.2 0.0 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease WCCH PF03716.9 EGC35871.1 - 0.15 11.5 0.0 0.22 10.9 0.0 1.3 1 0 0 1 1 1 0 WCCH motif ESCRT-II PF05871.7 EGC35872.1 - 3.6e-51 172.7 4.6 4.6e-51 172.4 3.2 1.1 1 0 0 1 1 1 1 ESCRT-II complex subunit Pkinase PF00069.20 EGC35873.1 - 4.1e-38 131.0 0.0 8.6e-38 129.9 0.0 1.5 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35873.1 - 1.1e-23 83.6 0.0 2.1e-23 82.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.7 EGC35873.1 - 2.5e-14 52.9 17.0 2.4e-07 30.6 0.0 6.3 5 1 2 7 7 7 2 FNIP Repeat Kinase-like PF14531.1 EGC35873.1 - 5.2e-05 22.3 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC35873.1 - 0.0066 16.2 0.0 0.011 15.5 0.0 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC35873.1 - 0.014 14.4 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC35873.1 - 0.018 14.3 0.0 0.033 13.5 0.0 1.4 1 0 0 1 1 1 0 PhoP regulatory network protein YrbL Choline_kinase PF01633.15 EGC35873.1 - 0.026 14.0 0.4 0.087 12.3 0.3 1.8 1 1 1 2 2 2 0 Choline/ethanolamine kinase RIO1 PF01163.17 EGC35873.1 - 0.033 13.5 0.0 0.06 12.6 0.0 1.3 1 0 0 1 1 1 0 RIO1 family DUF1769 PF08588.5 EGC35873.1 - 1.5 8.8 4.0 6.1 6.8 0.2 3.6 3 1 0 4 4 4 0 Protein of unknown function (DUF1769) Ras PF00071.17 EGC35874.1 - 1.9e-42 144.3 0.2 2.3e-42 144.1 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35874.1 - 6.4e-13 49.2 0.0 1.3e-12 48.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC35874.1 - 6.8e-13 48.2 0.1 8e-13 48.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC35874.1 - 9.6e-08 31.4 0.0 1.2e-07 31.0 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC35874.1 - 0.0097 15.8 0.0 0.017 15.0 0.0 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC35874.1 - 0.025 14.0 0.0 0.037 13.4 0.0 1.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain zf-CDGSH PF09360.5 EGC35875.1 - 4.7e-27 93.5 8.9 7e-14 51.3 0.9 2.3 2 0 0 2 2 2 2 Iron-binding zinc finger CDGSH type YgbA_NO PF11756.3 EGC35875.1 - 0.12 12.4 0.8 0.16 11.9 0.6 1.4 1 0 0 1 1 1 0 Nitrous oxide-stimulated promoter RRM_1 PF00076.17 EGC35876.1 - 2.3e-33 113.6 0.4 6e-18 64.2 0.1 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC35876.1 - 1e-22 79.8 0.1 2.4e-10 40.2 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC35876.1 - 2.9e-15 55.8 0.2 1.3e-08 34.5 0.0 2.2 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC35876.1 - 0.15 11.7 0.2 7.7 6.3 0.0 2.4 2 0 0 2 2 2 0 Limkain b1 Lactamase_B PF00753.22 EGC35877.1 - 3.1e-27 95.4 0.7 3.8e-27 95.2 0.5 1.1 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC35877.1 - 8.7e-09 35.2 0.1 1.2e-08 34.7 0.1 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGC35877.1 - 0.00022 20.9 0.1 0.00049 19.8 0.1 1.6 1 1 0 1 1 1 1 Beta-lactamase superfamily domain Glyco_transf_41 PF13844.1 EGC35878.1 - 4.9e-36 123.7 0.0 2.2e-20 72.1 0.0 2.2 1 1 1 2 2 2 2 Glycosyl transferase family 41 TPR_20 PF14561.1 EGC35878.1 - 8.9e-08 32.1 1.9 0.0094 16.0 0.2 2.7 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC35878.1 - 8.9e-07 29.1 2.1 4.3e-05 23.7 0.5 2.4 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC35878.1 - 3.7e-06 27.4 0.0 1.5e-05 25.5 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC35878.1 - 1.7e-05 24.3 1.1 1.7e-05 24.3 0.8 3.2 2 1 1 3 3 3 2 TPR repeat TPR_14 PF13428.1 EGC35878.1 - 2.1e-05 24.7 0.1 0.0015 18.9 0.0 2.9 2 1 1 3 3 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC35878.1 - 6.2e-05 22.8 4.6 0.16 12.2 0.5 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC35878.1 - 0.004 16.8 0.1 0.19 11.5 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC35878.1 - 0.0077 16.0 6.5 0.036 13.9 0.0 3.9 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC35878.1 - 0.016 14.7 6.4 0.35 10.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC35878.1 - 0.023 15.1 0.0 20 5.9 0.0 3.2 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC35878.1 - 1.4 8.9 5.9 1.1 9.2 0.2 3.1 1 1 3 4 4 4 0 Tetratricopeptide repeat Adenylsucc_synt PF00709.16 EGC35879.1 - 3.7e-173 576.0 0.0 4.2e-173 575.8 0.0 1.0 1 0 0 1 1 1 1 Adenylosuccinate synthetase NIF3 PF01784.13 EGC35879.1 - 0.07 12.6 0.0 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 NIF3 (NGG1p interacting factor 3) Alpha-amylase PF00128.19 EGC35880.1 - 3.3e-24 85.8 0.0 1.2e-23 83.9 0.0 1.9 1 1 0 1 1 1 1 Alpha amylase, catalytic domain DUF2922 PF11148.3 EGC35881.1 - 0.052 13.1 3.8 0.12 12.0 2.6 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2922) G6PD_N PF00479.17 EGC35881.1 - 0.067 13.4 2.8 0.08 13.1 1.9 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, NAD binding domain LMP PF04778.7 EGC35881.1 - 0.11 12.2 11.1 0.83 9.3 7.7 2.0 1 1 0 1 1 1 0 LMP repeated region DUF2514 PF10721.4 EGC35881.1 - 0.16 11.6 4.2 0.21 11.2 2.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) OEP PF02321.13 EGC35881.1 - 0.17 11.4 14.1 0.73 9.4 6.9 2.3 1 1 1 2 2 2 0 Outer membrane efflux protein Remorin_C PF03763.8 EGC35881.1 - 0.17 11.3 6.0 0.3 10.6 4.2 1.3 1 0 0 1 1 1 0 Remorin, C-terminal region TBPIP PF07106.8 EGC35881.1 - 0.67 9.4 13.7 0.097 12.2 6.1 1.9 1 1 1 2 2 2 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Kinesin-relat_1 PF12711.2 EGC35881.1 - 1.2 9.5 10.2 0.2 12.0 2.6 2.6 1 1 1 2 2 2 0 Kinesin motor Uds1 PF15456.1 EGC35881.1 - 1.4 8.8 9.8 0.95 9.4 4.7 1.9 2 0 0 2 2 2 0 Up-regulated During Septation DUF1635 PF07795.6 EGC35881.1 - 1.4 8.2 10.0 2.1 7.7 6.9 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF1635) Fib_alpha PF08702.5 EGC35881.1 - 1.8 8.6 13.9 4.2 7.5 7.8 2.2 1 1 1 2 2 2 0 Fibrinogen alpha/beta chain family AAA_23 PF13476.1 EGC35881.1 - 2 8.6 9.9 2.5 8.3 6.8 1.2 1 0 0 1 1 1 0 AAA domain Phlebovirus_NSM PF07246.6 EGC35881.1 - 2.1 7.4 10.6 5 6.1 7.3 1.7 1 1 0 1 1 1 0 Phlebovirus nonstructural protein NS-M DUF3847 PF12958.2 EGC35881.1 - 4.1 7.2 14.7 1.5 8.5 2.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3847) Atg14 PF10186.4 EGC35881.1 - 8 5.3 10.0 10 4.9 6.9 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 CactinC_cactus PF09732.4 EGC35882.1 - 1.6e-57 192.5 9.1 3.2e-57 191.5 6.3 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein Cactin_mid PF10312.4 EGC35882.1 - 7.1e-47 159.1 1.6 7.1e-47 159.1 1.1 2.5 2 0 0 2 2 2 1 Conserved mid region of cactin DUF2804 PF10974.3 EGC35884.1 - 2.2e-103 345.6 1.0 2.7e-103 345.3 0.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2804) SAP PF02037.22 EGC35886.1 - 0.0012 18.2 0.0 0.0023 17.3 0.0 1.5 1 0 0 1 1 1 1 SAP domain Nop14 PF04147.7 EGC35886.1 - 0.048 11.5 39.0 0.1 10.5 27.0 1.4 1 0 0 1 1 1 0 Nop14-like family Toxin_29 PF08116.6 EGC35886.1 - 1.2 8.9 5.2 3.6 7.4 0.6 2.7 2 0 0 2 2 2 0 PhTx neurotoxin family Zip PF02535.17 EGC35886.1 - 1.3 7.9 2.9 2.1 7.2 2.0 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter RP-C_C PF11800.3 EGC35886.1 - 4.5 6.9 6.8 9.7 5.8 4.7 1.5 1 0 0 1 1 1 0 Replication protein C C-terminal region HD_3 PF13023.1 EGC35887.1 - 6.2e-47 159.4 0.7 7.1e-47 159.2 0.5 1.1 1 0 0 1 1 1 1 HD domain HD PF01966.17 EGC35887.1 - 3.2e-07 30.3 0.1 7.1e-07 29.2 0.1 1.6 1 1 0 1 1 1 1 HD domain HD_2 PF12917.2 EGC35887.1 - 0.0027 17.5 0.2 0.0032 17.2 0.1 1.1 1 0 0 1 1 1 1 HD containing hydrolase-like enzyme PWI PF01480.12 EGC35887.1 - 0.0046 17.0 1.5 0.39 10.8 0.1 2.2 2 0 0 2 2 2 2 PWI domain HDOD PF08668.7 EGC35887.1 - 0.039 13.2 0.0 0.061 12.5 0.0 1.2 1 0 0 1 1 1 0 HDOD domain FadA PF09403.5 EGC35887.1 - 0.16 11.9 4.7 0.24 11.4 3.3 1.3 1 0 0 1 1 1 0 Adhesion protein FadA FNIP PF05725.7 EGC35888.1 - 5.6e-288 928.8 144.6 4.8e-15 55.2 0.0 18.3 6 3 17 25 25 25 25 FNIP Repeat Phage_min_tail PF05939.8 EGC35888.1 - 1.3e-18 66.9 7.6 6.7 6.7 0.0 15.7 6 4 11 17 17 17 5 Phage minor tail protein DUF1769 PF08588.5 EGC35888.1 - 0.043 13.7 55.9 5.2 7.0 0.2 16.6 7 6 14 22 22 22 0 Protein of unknown function (DUF1769) DUF3215 PF11503.3 EGC35888.1 - 0.1 12.2 0.9 22 4.7 0.0 5.0 4 2 2 6 6 6 0 Protein of unknown function (DUF3215) Terminase_1 PF03354.10 EGC35888.1 - 0.18 10.1 0.1 0.26 9.6 0.1 1.1 1 0 0 1 1 1 0 Phage Terminase FNIP PF05725.7 EGC35889.1 - 6.7e-69 227.6 23.5 1.6e-15 56.7 0.6 6.3 4 1 1 6 6 6 6 FNIP Repeat DUF3215 PF11503.3 EGC35889.1 - 0.028 14.0 0.1 0.97 9.1 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) EGF_2 PF07974.8 EGC35890.1 - 0.00079 19.5 11.6 0.00079 19.5 8.0 3.8 4 0 0 4 4 4 2 EGF-like domain PMP1_2 PF08114.6 EGC35890.1 - 0.00093 18.6 1.9 0.0023 17.3 1.3 1.6 1 0 0 1 1 1 1 ATPase proteolipid family Med10 PF09748.4 EGC35890.1 - 0.0069 16.2 2.2 0.018 14.8 1.5 1.6 1 0 0 1 1 1 1 Transcription factor subunit Med10 of Mediator complex Laminin_EGF PF00053.19 EGC35890.1 - 0.074 12.9 28.3 0.078 12.9 4.3 3.9 2 1 1 3 3 3 0 Laminin EGF-like (Domains III and V) TIG PF01833.19 EGC35891.1 - 0.00026 20.9 2.4 0.00026 20.9 1.6 3.7 2 1 1 3 3 3 1 IPT/TIG domain EGF_2 PF07974.8 EGC35891.1 - 0.00031 20.8 44.6 0.0015 18.6 10.4 3.2 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.19 EGC35891.1 - 0.7 9.8 32.1 0.99 9.3 10.1 3.1 2 1 0 2 2 2 0 Laminin EGF-like (Domains III and V) DUF3430 PF11912.3 EGC35892.1 - 1.2e-24 87.2 39.9 1.6e-24 86.9 27.7 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) WD40 PF00400.27 EGC35893.1 - 4.9e-59 194.2 21.8 7e-11 41.5 0.4 8.0 9 0 0 9 9 9 7 WD domain, G-beta repeat CLTH PF10607.4 EGC35893.1 - 1.2e-06 28.3 2.2 1.2e-06 28.3 1.5 1.8 2 0 0 2 2 2 1 CTLH/CRA C-terminal to LisH motif domain Nup160 PF11715.3 EGC35893.1 - 0.0077 14.4 4.5 1 7.4 0.5 3.6 1 1 0 2 2 2 2 Nucleoporin Nup120/160 Mem_trans PF03547.13 EGC35893.1 - 0.03 12.6 0.2 0.026 12.8 0.1 1.2 1 0 0 1 1 1 0 Membrane transport protein Glyco_trans_4_2 PF13477.1 EGC35893.1 - 0.052 13.3 0.8 3.7 7.3 0.1 2.5 2 0 0 2 2 2 0 Glycosyl transferase 4-like Erf4 PF10256.4 EGC35894.1 - 2.8e-27 94.9 1.2 3.1e-27 94.7 0.9 1.0 1 0 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ADH_N PF08240.7 EGC35895.1 - 1.9e-21 75.8 4.0 3.8e-21 74.9 2.7 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC35895.1 - 6.4e-15 54.8 0.0 1e-14 54.2 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase 2-Hacid_dh_C PF02826.14 EGC35895.1 - 0.0031 16.6 0.0 0.0053 15.9 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain ADH_zinc_N_2 PF13602.1 EGC35895.1 - 0.016 16.1 0.0 0.026 15.4 0.0 1.3 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ELFV_dehydrog PF00208.16 EGC35895.1 - 0.12 11.9 0.1 0.16 11.5 0.0 1.2 1 0 0 1 1 1 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Elf1 PF05129.8 EGC35895.1 - 0.7 9.6 4.7 3.8 7.2 0.1 3.0 3 1 0 3 3 3 0 Transcription elongation factor Elf1 like Adeno_E3 PF06040.6 EGC35896.1 - 0.15 12.0 3.3 0.2 11.6 2.0 1.4 1 1 1 2 2 2 0 Adenovirus E3 protein P34-Arc PF04045.9 EGC35896.1 - 0.56 9.4 4.0 3.3 6.9 1.3 2.6 1 1 1 2 2 2 0 Arp2/3 complex, 34 kD subunit p34-Arc Amidinotransf PF02274.12 EGC35896.1 - 3.6 6.5 9.3 61 2.5 6.4 2.1 1 1 0 1 1 1 0 Amidinotransferase Ribosomal_L25p PF01386.14 EGC35896.1 - 9.4 6.4 7.0 22 5.2 0.6 2.2 1 1 1 2 2 2 0 Ribosomal L25p family TIG PF01833.19 EGC35897.1 - 4.7e-07 29.7 0.3 4.7e-07 29.7 0.2 3.9 4 1 0 4 4 4 2 IPT/TIG domain EGF_2 PF07974.8 EGC35897.1 - 0.0021 18.1 13.5 0.0063 16.6 9.4 1.8 1 0 0 1 1 1 1 EGF-like domain LRR_4 PF12799.2 EGC35897.1 - 0.023 14.3 5.6 0.77 9.4 0.1 3.5 1 1 0 2 2 2 0 Leucine Rich repeats (2 copies) RmlD_sub_bind PF04321.12 EGC35898.1 - 2.7e-48 164.3 0.0 3.7e-48 163.8 0.0 1.1 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGC35898.1 - 2.6e-19 69.5 0.0 4.8e-19 68.7 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC35898.1 - 1.4e-08 33.9 0.0 7.4e-08 31.6 0.0 2.0 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_4 PF07993.7 EGC35898.1 - 0.00013 20.9 0.0 0.00021 20.2 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Pkinase_Tyr PF07714.12 EGC35899.1 - 1.3e-38 132.5 0.0 2.2e-38 131.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35899.1 - 5.7e-34 117.4 0.0 1.1e-33 116.5 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.18 EGC35899.1 - 5.5e-05 22.8 1.5 17 5.4 0.0 6.0 6 0 0 6 6 6 1 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC35899.1 - 0.00084 19.5 0.0 83 3.5 0.0 5.1 3 1 2 5 5 5 0 HEAT repeats Kinase-like PF14531.1 EGC35899.1 - 0.054 12.4 0.0 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Kinase-like HEAT PF02985.17 EGC35899.1 - 0.23 11.6 1.2 1.4e+02 2.9 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Peptidase_M24 PF00557.19 EGC35900.1 - 8e-46 156.2 0.1 1.2e-45 155.6 0.0 1.3 1 0 0 1 1 1 1 Metallopeptidase family M24 ADH_zinc_N PF00107.21 EGC35901.1 - 6.1e-21 74.3 0.0 1.1e-20 73.4 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC35901.1 - 0.00012 22.9 0.0 0.00028 21.7 0.0 1.7 2 0 0 2 2 2 1 Zinc-binding dehydrogenase PGM_PMM_II PF02879.11 EGC35901.1 - 0.038 14.2 0.2 0.27 11.5 0.0 2.4 3 0 0 3 3 3 0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II OTU PF02338.14 EGC35902.1 - 9e-13 48.8 0.1 1.9e-12 47.8 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease Neur_chan_memb PF02932.11 EGC35902.1 - 0.45 10.3 7.1 4.2 7.1 1.1 2.3 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Dicty_spore_N PF04562.7 EGC35905.1 - 1.5e-13 51.0 12.2 1.5e-13 51.0 8.5 4.3 2 1 2 4 4 4 1 Dictyostelium spore coat protein, N terminus DUF883 PF05957.8 EGC35906.1 - 9.4e-07 29.1 39.0 0.014 15.7 7.6 4.5 1 1 3 4 4 4 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGC35906.1 - 0.00034 20.1 24.9 0.019 14.5 17.2 2.5 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EGC35906.1 - 0.01 16.1 52.0 0.046 14.0 7.1 5.3 2 1 2 4 4 4 0 YtxH-like protein AT_hook PF02178.14 EGC35906.1 - 0.02 14.5 4.3 0.056 13.1 3.0 1.8 1 0 0 1 1 1 0 AT hook motif zf-UBR PF02207.15 EGC35906.1 - 0.042 13.5 8.4 0.51 10.1 0.7 2.3 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) LUC7 PF03194.10 EGC35906.1 - 0.093 12.2 35.7 0.035 13.6 5.2 2.5 1 1 1 2 2 2 0 LUC7 N_terminus DBD_Tnp_Hermes PF10683.4 EGC35906.1 - 0.46 9.9 8.0 1.3 8.5 0.9 2.8 2 0 0 2 2 2 0 Hermes transposase DNA-binding domain Prenyltransf PF01255.14 EGC35906.1 - 0.54 9.3 13.5 0.38 9.8 6.6 2.3 1 1 1 2 2 2 0 Putative undecaprenyl diphosphate synthase Prominin PF05478.6 EGC35906.1 - 1.3 6.4 22.8 3.2 5.1 15.8 1.7 1 1 0 1 1 1 0 Prominin Synuclein PF01387.12 EGC35906.1 - 1.9 8.4 39.7 19 5.1 15.2 4.3 1 1 3 4 4 4 0 Synuclein Lipase_GDSL PF00657.17 EGC35906.1 - 3.8 7.2 7.5 1.4 8.7 0.3 2.5 1 1 0 2 2 2 0 GDSL-like Lipase/Acylhydrolase DUF3619 PF12279.3 EGC35906.1 - 5.5 7.0 12.4 0.047 13.7 1.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3619) Syntaxin_2 PF14523.1 EGC35906.1 - 5.7 7.0 26.5 7.8 6.5 2.5 4.4 1 1 3 4 4 4 0 Syntaxin-like protein Zn_Tnp_IS91 PF14319.1 EGC35906.1 - 9.3 5.7 12.7 7.1 6.1 1.4 2.6 2 0 0 2 2 2 0 Transposase zinc-binding domain LEA_4 PF02987.11 EGC35907.1 - 0.019 14.8 0.1 0.019 14.8 0.1 2.6 4 0 0 4 4 4 0 Late embryogenesis abundant protein Spt20 PF12090.3 EGC35908.1 - 2.7e-33 114.8 5.4 2.7e-33 114.8 3.7 2.2 1 1 0 2 2 2 1 Spt20 family SEP PF08059.8 EGC35908.1 - 0.074 13.3 3.3 0.21 11.9 0.1 2.7 2 0 0 2 2 2 0 SEP domain Podoplanin PF05808.6 EGC35908.1 - 5.1 6.6 8.3 8.3 5.9 5.8 1.4 1 0 0 1 1 1 0 Podoplanin ubiquitin PF00240.18 EGC35909.1 - 1.8e-10 40.0 0.0 2.1e-10 39.8 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGC35909.1 - 0.0058 16.8 0.0 0.018 15.2 0.0 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain AICARFT_IMPCHas PF01808.13 EGC35910.1 - 1.8e-98 329.4 0.0 2.4e-98 329.1 0.0 1.1 1 0 0 1 1 1 1 AICARFT/IMPCHase bienzyme MGS PF02142.17 EGC35910.1 - 3e-25 87.9 0.1 1.2e-24 86.0 0.0 2.1 2 0 0 2 2 2 1 MGS-like domain DUF2930 PF11152.3 EGC35910.1 - 0.0066 15.6 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2930) HCaRG PF07258.9 EGC35911.1 - 9.4e-47 158.8 1.5 1e-46 158.6 1.1 1.0 1 0 0 1 1 1 1 HCaRG protein Pho88 PF10032.4 EGC35911.1 - 0.059 12.5 0.1 0.1 11.8 0.1 1.3 1 0 0 1 1 1 0 Phosphate transport (Pho88) DUF211 PF02680.9 EGC35911.1 - 0.13 12.0 1.7 0.24 11.2 0.9 1.6 1 1 0 1 1 1 0 Uncharacterized ArCR, COG1888 DUF1084 PF06454.6 EGC35912.1 - 3.9e-93 311.5 13.4 4.8e-93 311.2 9.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF912 PF06024.7 EGC35912.1 - 0.55 10.3 10.4 8.9 6.4 0.6 4.1 3 1 1 4 4 4 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF373 PF04123.8 EGC35912.1 - 8.8 5.2 8.8 2.3 7.1 1.9 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF373) DUF1084 PF06454.6 EGC35913.1 - 0.014 14.4 4.6 0.019 14.0 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1084) LicD PF04991.8 EGC35913.1 - 0.24 11.5 16.0 0.34 10.9 11.1 1.2 1 0 0 1 1 1 0 LicD family EGF_2 PF07974.8 EGC35914.1 - 0.0009 19.3 8.0 0.0015 18.6 5.5 1.4 1 0 0 1 1 1 1 EGF-like domain DUF1673 PF07895.6 EGC35914.1 - 0.0079 15.7 2.1 0.0093 15.5 1.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) Claudin_2 PF13903.1 EGC35914.1 - 0.062 12.9 0.3 0.069 12.8 0.2 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction EGF PF00008.22 EGC35914.1 - 0.13 12.2 6.0 0.23 11.4 4.2 1.5 1 0 0 1 1 1 0 EGF-like domain PLAC8 PF04749.12 EGC35915.1 - 1e-11 45.2 16.4 1.3e-11 45.0 11.4 1.1 1 0 0 1 1 1 1 PLAC8 family DUF383 PF04063.9 EGC35916.1 - 1e-39 136.0 0.7 1e-39 136.0 0.5 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF383) DUF384 PF04064.8 EGC35916.1 - 4.5e-16 58.1 0.1 1.4e-15 56.5 0.1 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF384) tRNA_synt_1c_R1 PF04558.10 EGC35916.1 - 0.009 15.5 0.4 0.021 14.3 0.3 1.6 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 HEAT_2 PF13646.1 EGC35916.1 - 0.024 14.8 0.0 11 6.3 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats PcfK PF14058.1 EGC35916.1 - 0.07 13.2 0.3 0.19 11.8 0.2 1.7 1 0 0 1 1 1 0 PcfK-like protein Rad21_Rec8_N PF04825.8 EGC35917.1 - 5.5e-38 129.3 0.1 1.1e-37 128.3 0.0 1.5 1 0 0 1 1 1 1 N terminus of Rad21 / Rec8 like protein Rad21_Rec8 PF04824.11 EGC35917.1 - 3.5e-05 22.9 0.1 0.00039 19.5 0.0 2.4 2 0 0 2 2 2 1 Conserved region of Rad21 / Rec8 like protein Lact-deh-memb PF09330.6 EGC35917.1 - 0.079 12.3 0.1 0.15 11.3 0.1 1.4 1 0 0 1 1 1 0 D-lactate dehydrogenase, membrane binding SLBP_RNA_bind PF15247.1 EGC35918.1 - 2.7e-21 75.1 0.2 4.1e-21 74.5 0.1 1.4 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain FHA PF00498.21 EGC35919.1 - 9e-16 57.7 0.0 2.3e-15 56.4 0.0 1.7 1 0 0 1 1 1 1 FHA domain Pkinase PF00069.20 EGC35920.1 - 9.9e-66 221.5 0.0 9.9e-66 221.5 0.0 2.1 2 1 0 2 2 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC35920.1 - 1.7e-35 122.3 0.0 2.8e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PAS_9 PF13426.1 EGC35920.1 - 4.5e-24 84.8 1.2 2.6e-09 37.4 0.0 4.4 3 1 0 3 3 3 3 PAS domain PAS PF00989.19 EGC35920.1 - 2.2e-23 82.1 0.0 3.3e-08 33.2 0.0 3.7 3 0 0 3 3 3 3 PAS fold PAS_4 PF08448.5 EGC35920.1 - 8.5e-08 32.2 0.0 0.00058 19.8 0.0 3.2 3 0 0 3 3 3 2 PAS fold PAS_8 PF13188.1 EGC35920.1 - 4e-06 26.4 0.0 0.059 13.2 0.0 3.3 3 0 0 3 3 3 2 PAS domain Kinase-like PF14531.1 EGC35920.1 - 7.5e-06 25.1 0.0 2.7e-05 23.3 0.0 1.9 2 0 0 2 2 2 1 Kinase-like PAS_3 PF08447.6 EGC35920.1 - 8.3e-06 25.8 0.0 0.058 13.4 0.0 3.4 3 0 0 3 3 3 2 PAS fold Kdo PF06293.9 EGC35920.1 - 8.1e-05 21.7 0.7 0.0002 20.5 0.1 1.9 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family CDC45 PF02724.9 EGC35920.1 - 0.00055 18.1 12.2 0.00055 18.1 8.4 2.0 2 0 0 2 2 2 1 CDC45-like protein Mem_trans PF03547.13 EGC35920.1 - 0.0037 15.6 1.4 0.0037 15.6 1.0 2.9 3 0 0 3 3 3 1 Membrane transport protein APH PF01636.18 EGC35920.1 - 0.079 12.6 0.3 0.14 11.8 0.2 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family COX16 PF14138.1 EGC35921.1 - 1e-07 31.9 0.4 2.2e-06 27.7 0.3 2.0 1 1 0 1 1 1 1 Cytochrome c oxidase assembly protein COX16 DUF3357 PF11837.3 EGC35925.1 - 0.018 14.8 1.2 0.78 9.6 0.0 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) MerC PF03203.9 EGC35925.1 - 0.023 15.0 7.7 0.028 14.8 5.3 1.2 1 0 0 1 1 1 0 MerC mercury resistance protein Ninjurin PF04923.7 EGC35925.1 - 0.023 14.4 0.7 0.19 11.4 0.2 2.0 2 0 0 2 2 2 0 Ninjurin ATG19_autophagy PF12744.2 EGC35925.1 - 0.15 11.3 3.2 3.6 6.7 0.0 2.8 1 1 2 3 3 3 0 Autophagy protein Atg19, Atg8-binding Metal_resist PF13801.1 EGC35925.1 - 0.32 11.0 7.8 0.36 10.8 0.8 2.8 2 1 1 3 3 3 0 Heavy-metal resistance Plant_vir_prot PF01307.12 EGC35925.1 - 0.36 10.5 4.2 6.1 6.6 0.1 2.3 1 1 1 2 2 2 0 Plant viral movement protein CD20 PF04103.10 EGC35925.1 - 0.56 10.1 4.9 29 4.5 3.3 2.7 1 1 0 1 1 1 0 CD20-like family DUF1980 PF09323.5 EGC35925.1 - 4.1 7.1 13.0 0.16 11.7 4.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF1980) Phosphonate-bd PF12974.2 EGC35926.1 - 3.5e-23 82.2 0.0 5.1e-23 81.7 0.0 1.2 1 0 0 1 1 1 1 ABC transporter, phosphonate, periplasmic substrate-binding protein NMT1 PF09084.6 EGC35926.1 - 0.047 13.2 0.0 0.075 12.6 0.0 1.3 1 0 0 1 1 1 0 NMT1/THI5 like Rho_GDI PF02115.12 EGC35927.1 - 4.4e-05 22.9 0.0 4.9e-05 22.8 0.0 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor Ras PF00071.17 EGC35930.1 - 1.6e-65 219.4 0.2 1.8e-65 219.2 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35930.1 - 4.6e-20 72.2 0.0 8.4e-20 71.4 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC35930.1 - 1.6e-14 53.5 0.1 2e-14 53.2 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC35930.1 - 6.3e-07 28.7 0.0 7.7e-07 28.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC35930.1 - 5.3e-06 25.9 0.1 1.8e-05 24.2 0.1 1.8 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC35930.1 - 0.00013 21.9 0.0 0.00034 20.5 0.0 1.7 1 1 1 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC35930.1 - 0.00073 18.7 0.0 0.0018 17.4 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 SRPRB PF09439.5 EGC35930.1 - 0.0039 16.4 0.0 0.0072 15.5 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC35930.1 - 0.031 12.9 1.8 2.8 6.5 0.0 2.7 2 1 1 3 3 3 0 G-protein alpha subunit AAA_29 PF13555.1 EGC35930.1 - 0.04 13.4 0.0 0.1 12.1 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC35930.1 - 0.069 13.1 0.0 0.11 12.4 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain DUF3963 PF13124.1 EGC35930.1 - 0.07 12.9 0.3 0.15 11.8 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3963) AAA_5 PF07728.9 EGC35930.1 - 0.074 12.7 0.0 0.16 11.7 0.0 1.6 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC35930.1 - 0.086 12.9 0.0 0.13 12.3 0.0 1.6 1 1 0 1 1 1 0 AAA domain MCM PF00493.18 EGC35930.1 - 0.1 11.3 0.0 0.27 9.9 0.0 1.6 2 0 0 2 2 2 0 MCM2/3/5 family Peptidase_C26 PF07722.8 EGC35931.1 - 0.0034 16.8 0.0 0.0046 16.4 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EGC35931.1 - 0.018 14.5 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Glutamine amidotransferase class-I Ras PF00071.17 EGC35932.1 - 3.5e-56 189.0 0.1 4.3e-56 188.7 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC35932.1 - 8.2e-19 68.2 0.0 1.2e-18 67.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC35932.1 - 4.7e-13 48.7 0.1 5.4e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC35932.1 - 0.00092 18.4 0.0 0.0011 18.1 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC35932.1 - 0.0053 16.2 0.0 0.0068 15.8 0.0 1.3 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC35932.1 - 0.009 15.9 0.2 0.018 14.9 0.1 1.6 1 1 0 1 1 1 1 50S ribosome-binding GTPase NTPase_1 PF03266.10 EGC35932.1 - 0.055 13.1 0.0 0.075 12.7 0.0 1.4 1 0 0 1 1 1 0 NTPase EF-hand_7 PF13499.1 EGC35933.1 - 1.8e-18 66.3 6.1 1.3e-11 44.4 0.6 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC35933.1 - 1.9e-16 58.0 9.9 1.4e-05 24.0 0.2 4.1 4 1 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC35933.1 - 1.8e-15 56.3 3.5 1.3e-06 27.9 0.0 3.5 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC35933.1 - 8.9e-15 53.1 4.8 0.00036 20.1 0.0 4.2 4 0 0 4 4 4 3 EF-hand domain EF-hand_5 PF13202.1 EGC35933.1 - 9.8e-15 53.1 7.9 7.7e-06 25.0 0.2 4.1 5 0 0 5 5 5 3 EF hand SPARC_Ca_bdg PF10591.4 EGC35933.1 - 1.6e-10 40.9 1.5 1.2e-06 28.5 0.5 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region Transposase_mut PF00872.13 EGC35933.1 - 0.043 12.3 0.3 0.1 11.0 0.2 1.5 1 1 1 2 2 2 0 Transposase, Mutator family EF-hand_10 PF14788.1 EGC35933.1 - 0.063 12.9 8.5 6.9 6.4 0.2 4.5 3 1 1 4 4 4 0 EF hand EF-hand_4 PF12763.2 EGC35933.1 - 0.31 10.8 6.1 1.3 8.8 1.3 2.3 1 1 1 2 2 2 0 Cytoskeletal-regulatory complex EF hand Mito_carr PF00153.22 EGC35934.1 - 2.6e-70 232.1 1.2 2e-22 78.6 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Ras PF00071.17 EGC35935.1 - 3.5e-09 36.2 4.7 5.1e-07 29.2 0.1 3.8 4 0 0 4 4 4 2 Ras family Miro PF08477.8 EGC35935.1 - 0.00012 22.5 1.1 0.0035 17.8 0.3 3.6 2 1 0 2 2 2 1 Miro-like protein Aldedh PF00171.17 EGC35935.1 - 0.092 11.0 0.1 0.16 10.2 0.0 1.2 1 0 0 1 1 1 0 Aldehyde dehydrogenase family UAA PF08449.6 EGC35936.1 - 0.018 13.9 0.1 0.02 13.8 0.1 1.1 1 0 0 1 1 1 0 UAA transporter family Enolase_C PF00113.17 EGC35938.1 - 2.7e-126 420.5 0.0 3.6e-126 420.1 0.0 1.1 1 0 0 1 1 1 1 Enolase, C-terminal TIM barrel domain Enolase_N PF03952.11 EGC35938.1 - 1.1e-59 200.1 0.2 1.8e-59 199.4 0.1 1.3 1 0 0 1 1 1 1 Enolase, N-terminal domain MAAL_C PF07476.6 EGC35938.1 - 9.2e-05 21.4 0.3 0.00045 19.2 0.0 1.9 2 0 0 2 2 2 1 Methylaspartate ammonia-lyase C-terminus MR_MLE_C PF13378.1 EGC35938.1 - 0.00074 19.4 0.0 0.0016 18.3 0.0 1.6 1 0 0 1 1 1 1 Enolase C-terminal domain-like MR_MLE PF01188.16 EGC35938.1 - 0.019 15.4 0.0 0.062 13.8 0.0 1.9 2 0 0 2 2 2 0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain DUF2273 PF10031.4 EGC35939.1 - 0.02 14.5 1.0 0.039 13.5 0.7 1.4 1 0 0 1 1 1 0 Small integral membrane protein (DUF2273) MIP-T3 PF10243.4 EGC35939.1 - 0.32 9.4 36.6 0.46 8.8 25.4 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 Utp14 PF04615.8 EGC35939.1 - 4.8 5.2 41.8 7 4.6 29.0 1.1 1 0 0 1 1 1 0 Utp14 protein CRISPR_Cas2 PF09827.4 EGC35940.1 - 0.064 13.4 0.0 0.19 11.8 0.0 1.9 2 1 0 2 2 2 0 CRISPR associated protein Cas2 Capsid_NCLDV PF04451.7 EGC35941.1 - 0.0046 15.9 0.1 0.0048 15.9 0.1 1.1 1 0 0 1 1 1 1 Large eukaryotic DNA virus major capsid protein ATP-synt_ab PF00006.20 EGC35942.1 - 1.2e-113 377.8 0.0 1.8e-113 377.3 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGC35942.1 - 3.7e-23 82.1 0.2 6.7e-23 81.3 0.2 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGC35942.1 - 1.4e-15 57.2 2.7 4.7e-15 55.5 0.6 2.7 3 0 0 3 3 3 1 ATP synthase alpha/beta family, beta-barrel domain LSM PF01423.17 EGC35943.1 - 6.9e-16 57.5 0.4 1e-15 56.9 0.3 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC35943.1 - 0.011 15.6 0.0 0.015 15.1 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Feld-I_B PF09252.5 EGC35943.1 - 0.026 14.4 0.0 0.037 13.9 0.0 1.2 1 0 0 1 1 1 0 Allergen Fel d I-B chain Rad52_Rad22 PF04098.10 EGC35944.1 - 3.3e-31 108.0 0.8 5.4e-31 107.4 0.6 1.3 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein Mgm101p PF06420.7 EGC35944.1 - 0.11 11.7 0.0 0.17 11.2 0.0 1.4 1 0 0 1 1 1 0 Mitochondrial genome maintenance MGM101 Arch_ATPase PF01637.13 EGC35945.1 - 0.00041 20.1 0.1 0.00071 19.3 0.1 1.5 1 1 0 1 1 1 1 Archaeal ATPase AAA_14 PF13173.1 EGC35945.1 - 0.0019 18.1 0.2 0.0019 18.1 0.2 2.2 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EGC35945.1 - 0.0075 15.4 0.0 0.014 14.5 0.0 1.4 1 0 0 1 1 1 1 KaiC Fer2_3 PF13085.1 EGC35945.1 - 0.13 12.1 0.8 0.28 11.0 0.5 1.8 1 1 1 2 2 2 0 2Fe-2S iron-sulfur cluster binding domain AAA_23 PF13476.1 EGC35945.1 - 1.4 9.2 13.7 42 4.3 9.5 2.7 1 1 0 1 1 1 0 AAA domain TSA PF03249.8 EGC35945.1 - 3.3 6.1 8.5 5.4 5.4 5.9 1.3 1 0 0 1 1 1 0 Type specific antigen HMG_box PF00505.14 EGC35946.1 - 1.8e-06 28.0 5.2 1.8e-06 28.0 3.6 3.6 4 0 0 4 4 4 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGC35946.1 - 2.6e-05 24.4 3.1 2.6e-05 24.4 2.2 4.3 4 0 0 4 4 4 1 HMG-box domain TFIIA PF03153.8 EGC35946.1 - 0.17 11.7 55.1 0.37 10.6 38.2 1.6 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Pur_DNA_glyco PF02245.11 EGC35946.1 - 1.1 8.3 4.2 0.62 9.1 0.7 1.9 2 0 0 2 2 2 0 Methylpurine-DNA glycosylase (MPG) DIRP PF06584.8 EGC35947.1 - 5.7e-16 58.3 2.3 5.7e-16 58.3 1.6 2.9 2 0 0 2 2 2 2 DIRP ACOX PF01756.14 EGC35948.1 - 4.4e-30 104.4 0.5 7.7e-30 103.6 0.3 1.4 1 0 0 1 1 1 1 Acyl-CoA oxidase Acyl-CoA_dh_M PF02770.14 EGC35948.1 - 9e-17 60.3 0.2 1.8e-16 59.3 0.2 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_1 PF00441.19 EGC35948.1 - 3.3e-05 24.0 0.0 7.5e-05 22.8 0.0 1.6 1 1 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DapH_N PF08503.5 EGC35949.1 - 0.0033 17.4 0.1 0.0052 16.8 0.0 1.5 1 1 0 1 1 1 1 Tetrahydrodipicolinate succinyltransferase N-terminal Mga PF05043.8 EGC35950.1 - 0.018 15.3 0.2 0.053 13.8 0.1 1.8 1 0 0 1 1 1 0 Mga helix-turn-helix domain EGF_2 PF07974.8 EGC35950.1 - 0.03 14.4 12.1 0.075 13.2 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain VirDNA-topo-I_N PF09266.5 EGC35950.1 - 0.043 13.7 0.2 0.043 13.7 0.2 2.2 2 0 0 2 2 2 0 Viral DNA topoisomerase I, N-terminal Sulfate_transp PF00916.15 EGC35951.1 - 1.3e-68 231.0 13.2 1.3e-68 231.0 9.2 1.6 2 0 0 2 2 2 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGC35951.1 - 2.6e-32 110.3 5.6 8.8e-32 108.6 3.9 2.0 1 0 0 1 1 1 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGC35951.1 - 2.6e-18 65.5 0.1 5e-18 64.6 0.1 1.5 1 0 0 1 1 1 1 STAS domain Remorin_N PF03766.8 EGC35952.1 - 5.2 6.9 7.5 4.5 7.1 0.8 2.7 1 1 1 2 2 2 0 Remorin, N-terminal region NAD_binding_10 PF13460.1 EGC35953.1 - 4.8e-18 65.8 0.0 2.6e-17 63.4 0.0 1.9 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGC35953.1 - 1.9e-15 56.7 0.0 1.4e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 NmrA-like family Semialdhyde_dh PF01118.19 EGC35953.1 - 2.4e-05 24.6 0.0 5.3e-05 23.4 0.0 1.5 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Saccharop_dh PF03435.13 EGC35953.1 - 0.00012 21.1 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase 3Beta_HSD PF01073.14 EGC35953.1 - 0.00014 20.6 0.0 0.018 13.7 0.0 2.7 2 1 1 3 3 3 2 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC35953.1 - 0.00094 18.6 0.0 0.0015 18.0 0.0 1.3 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGC35953.1 - 0.015 15.4 0.0 0.029 14.4 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase TrkA_N PF02254.13 EGC35953.1 - 0.037 14.0 0.0 0.059 13.3 0.0 1.3 1 0 0 1 1 1 0 TrkA-N domain DapB_N PF01113.15 EGC35953.1 - 0.075 12.9 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Polysacc_synt_2 PF02719.10 EGC35953.1 - 0.13 11.1 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein GAF_2 PF13185.1 EGC35954.1 - 0.0015 19.0 0.0 0.0023 18.4 0.0 1.2 1 0 0 1 1 1 1 GAF domain Profilin PF00235.14 EGC35955.1 - 3e-30 104.8 0.0 7.2e-30 103.5 0.0 1.7 1 0 0 1 1 1 1 Profilin DUF2457 PF10446.4 EGC35955.1 - 0.35 9.5 23.1 0.54 8.9 16.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGC35955.1 - 4.5 5.1 18.1 7 4.5 12.5 1.3 1 0 0 1 1 1 0 CDC45-like protein HAD PF12710.2 EGC35956.1 - 5.7e-15 55.9 0.0 1.9e-14 54.2 0.0 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase E1-E2_ATPase PF00122.15 EGC35956.1 - 9.3e-14 51.0 0.0 9.3e-14 51.0 0.0 2.5 3 0 0 3 3 3 1 E1-E2 ATPase Hydrolase PF00702.21 EGC35956.1 - 3.5e-11 43.9 0.1 7.2e-10 39.6 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC35956.1 - 2e-10 40.4 4.3 7.2e-10 38.6 0.3 3.0 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Rhomboid PF01694.17 EGC35957.1 - 4.4e-12 46.2 7.8 4.4e-12 46.2 5.4 1.8 2 0 0 2 2 2 1 Rhomboid family DUF1751 PF08551.5 EGC35957.1 - 0.013 15.7 4.2 0.013 15.7 2.9 2.2 1 1 1 2 2 2 0 Eukaryotic integral membrane protein (DUF1751) DER1 PF04511.10 EGC35957.1 - 0.17 11.3 16.9 0.48 9.8 11.7 1.8 1 1 0 1 1 1 0 Der1-like family FNIP PF05725.7 EGC35958.1 - 3.5e-24 84.4 62.5 1.2e-11 44.3 3.8 11.6 9 3 2 11 11 11 10 FNIP Repeat DUF1576 PF07613.6 EGC35960.1 - 0.049 13.1 0.1 0.057 12.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1576) Adeno_E3_CR2 PF02439.10 EGC35960.1 - 0.082 12.4 0.1 0.13 11.7 0.1 1.5 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 FNIP PF05725.7 EGC35961.1 - 1.2e-23 82.7 31.6 1.9e-13 50.1 1.6 11.8 7 5 3 10 10 10 7 FNIP Repeat LRR_8 PF13855.1 EGC35961.1 - 0.0034 17.1 2.8 0.0034 17.1 1.9 6.6 9 0 0 9 9 9 1 Leucine rich repeat ICL PF00463.16 EGC35961.1 - 0.039 12.1 0.1 0.06 11.5 0.1 1.2 1 0 0 1 1 1 0 Isocitrate lyase family DUF2344 PF10105.4 EGC35961.1 - 0.095 12.1 0.1 0.3 10.5 0.0 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2344) Brr6_like_C_C PF10104.4 EGC35963.1 - 7.4 6.0 6.8 0.8 9.2 0.6 2.2 3 0 0 3 3 3 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF1192 PF06698.6 EGC35964.1 - 0.19 11.5 1.6 0.36 10.6 1.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1192) DUF543 PF04418.7 EGC35964.1 - 2.3 8.2 4.7 0.52 10.3 0.7 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF543) tRNA-synt_2d PF01409.15 EGC35965.1 - 1.6e-89 299.3 0.2 2.7e-89 298.6 0.0 1.4 2 0 0 2 2 2 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGC35965.1 - 9.9e-08 31.7 0.0 2e-07 30.7 0.0 1.5 1 1 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) tRNA-synt_2 PF00152.15 EGC35965.1 - 1.9e-05 23.6 6.3 2.5e-05 23.2 0.0 2.9 2 1 1 3 3 3 1 tRNA synthetases class II (D, K and N) Pkinase_Tyr PF07714.12 EGC35966.1 - 8.7e-62 208.5 0.0 1.2e-61 208.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC35966.1 - 2.5e-54 184.1 0.0 3.3e-54 183.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC35966.1 - 8e-06 25.0 0.0 1.3e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC35966.1 - 0.00027 20.7 0.0 0.0033 17.1 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family RIO1 PF01163.17 EGC35966.1 - 0.00029 20.2 2.6 0.0067 15.7 0.1 2.5 1 1 1 2 2 2 2 RIO1 family Kdo PF06293.9 EGC35966.1 - 0.0097 14.9 0.0 0.013 14.5 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family LIM PF00412.17 EGC35967.1 - 1.1e-15 57.4 15.6 3.2e-10 39.9 5.2 2.1 2 0 0 2 2 2 2 LIM domain DUF1033 PF06279.6 EGC35967.1 - 0.1 12.3 1.8 0.15 11.9 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1033) YhfH PF14149.1 EGC35967.1 - 0.71 9.7 0.1 0.71 9.7 0.0 3.4 3 1 0 3 3 3 0 YhfH-like protein Gin PF10764.4 EGC35967.1 - 1.5 8.6 13.8 16 5.3 5.8 3.1 1 1 1 2 2 2 0 Inhibitor of sigma-G Gin zf-C3HC4_2 PF13923.1 EGC35967.1 - 1.7 8.7 10.9 31 4.7 0.8 3.4 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) DUF1451 PF07295.6 EGC35967.1 - 3.2 7.5 8.8 0.46 10.2 3.2 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1451) Zn_Tnp_IS1595 PF12760.2 EGC35967.1 - 5.8 6.8 13.2 0.12 12.1 1.4 2.9 2 2 0 2 2 2 0 Transposase zinc-ribbon domain DZR PF12773.2 EGC35967.1 - 6.7 6.6 16.3 1.4e+02 2.3 11.3 3.0 1 1 0 1 1 1 0 Double zinc ribbon bZIP_1 PF00170.16 EGC35968.1 - 0.054 13.4 1.8 0.16 11.9 0.9 2.2 1 1 0 1 1 1 0 bZIP transcription factor TSC22 PF01166.13 EGC35968.1 - 8.3 6.4 7.9 4.8 7.2 2.0 3.0 2 1 1 3 3 3 0 TSC-22/dip/bun family DUF4442 PF14539.1 EGC35969.1 - 0.0073 16.2 0.1 0.01 15.8 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4442) DUF3567 PF12091.3 EGC35971.1 - 0.032 14.2 0.4 40 4.2 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3567) DUF2200 PF09966.4 EGC35971.1 - 0.039 13.8 0.0 0.36 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2200) RED_N PF07808.8 EGC35972.1 - 1e-20 74.0 27.9 1.5e-19 70.2 9.4 5.2 3 2 2 5 5 5 2 RED-like protein N-terminal region NUDIX PF00293.23 EGC35973.1 - 7.7e-15 54.7 0.0 2.1e-14 53.3 0.0 1.6 2 0 0 2 2 2 1 NUDIX domain zf-Di19 PF05605.7 EGC35973.1 - 0.0022 18.0 5.9 0.0093 16.0 4.1 2.1 1 1 0 1 1 1 1 Drought induced 19 protein (Di19), zinc-binding DUF3873 PF12989.2 EGC35973.1 - 0.11 12.6 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function, B. Theta Gene description (DUF3873) TruD PF01142.13 EGC35975.1 - 1.1e-61 208.5 0.0 3.7e-60 203.5 0.0 2.4 2 1 0 2 2 2 2 tRNA pseudouridine synthase D (TruD) Not3 PF04065.10 EGC35976.1 - 2.5e-57 193.8 19.3 2.5e-57 193.8 13.4 3.3 3 0 0 3 3 3 1 Not1 N-terminal domain, CCR4-Not complex component NOT2_3_5 PF04153.13 EGC35976.1 - 8.7e-39 132.4 4.7 8.7e-39 132.4 3.3 5.1 4 2 0 4 4 4 1 NOT2 / NOT3 / NOT5 family VPS9 PF02204.13 EGC35977.1 - 7.7e-27 93.3 1.6 1.2e-26 92.7 1.1 1.3 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain DNA_RNApol_7kD PF03604.8 EGC35978.1 - 2.1e-16 59.1 7.2 2.6e-16 58.7 5.0 1.1 1 0 0 1 1 1 1 DNA directed RNA polymerase, 7 kDa subunit Zn_ribbon_recom PF13408.1 EGC35978.1 - 0.023 14.9 2.5 1.6 9.0 0.3 2.1 2 0 0 2 2 2 0 Recombinase zinc beta ribbon domain DUF2082 PF09855.4 EGC35978.1 - 0.037 13.8 1.0 0.037 13.8 0.7 1.7 1 1 1 2 2 2 0 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) DZR PF12773.2 EGC35978.1 - 0.04 13.7 2.8 0.053 13.3 2.0 1.1 1 0 0 1 1 1 0 Double zinc ribbon HypA PF01155.14 EGC35978.1 - 0.044 13.4 0.4 0.045 13.4 0.3 1.1 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family OrfB_Zn_ribbon PF07282.6 EGC35978.1 - 0.094 12.3 1.1 0.12 12.0 0.8 1.2 1 0 0 1 1 1 0 Putative transposase DNA-binding domain DUF2616 PF11077.3 EGC35978.1 - 0.1 12.0 1.3 0.12 11.8 0.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2616) A2L_zn_ribbon PF08792.5 EGC35978.1 - 0.14 11.6 5.3 0.33 10.4 0.1 2.4 2 1 0 2 2 2 0 A2L zinc ribbon domain zf-trcl PF13451.1 EGC35978.1 - 6.6 6.4 5.9 2.4 7.8 0.4 2.1 1 1 1 2 2 2 0 Probable zinc-binding domain Mito_carr PF00153.22 EGC35979.1 - 6.6e-71 234.1 0.4 7.9e-23 79.9 0.0 3.2 3 0 0 3 3 3 3 Mitochondrial carrier protein Spc7 PF08317.6 EGC35979.1 - 0.073 11.7 10.2 0.12 11.0 7.1 1.2 1 0 0 1 1 1 0 Spc7 kinetochore protein zf-C4H2 PF10146.4 EGC35979.1 - 1 9.3 6.5 1.6 8.7 4.5 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein IncA PF04156.9 EGC35979.1 - 4.8 6.7 7.3 7.9 6.0 5.1 1.3 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 EGC35983.1 - 1.4e-17 62.8 13.8 6.4e-07 29.0 0.0 4.9 5 0 0 5 5 5 4 WD domain, G-beta repeat ImmE5 PF11480.3 EGC35983.1 - 5.7 6.8 8.7 13 5.6 0.0 3.1 2 0 0 2 2 2 0 Colicin-E5 Imm protein DDE_Tnp_4 PF13359.1 EGC35985.1 - 4.3e-05 23.1 2.1 5.3e-05 22.8 1.4 1.3 1 1 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC35985.1 - 0.078 12.5 1.5 0.13 11.7 0.3 1.8 1 1 1 2 2 2 0 Transposase DDE domain CRAL_TRIO PF00650.15 EGC35986.1 - 4.1e-26 91.3 0.5 6.1e-26 90.8 0.3 1.2 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_2 PF13716.1 EGC35986.1 - 2.2e-05 24.3 1.0 3.8e-05 23.6 0.7 1.4 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain DUF3791 PF12668.2 EGC35986.1 - 0.11 12.0 1.0 0.27 10.8 0.3 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3791) G8 PF10162.4 EGC35987.1 - 0.044 13.5 12.7 0.14 11.9 0.2 4.2 3 3 0 3 3 3 0 G8 domain DUF2613 PF11021.3 EGC35987.1 - 4.3 7.1 6.3 12 5.6 4.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PX PF00787.19 EGC35989.1 - 0.033 13.9 2.9 0.051 13.3 2.0 1.3 1 0 0 1 1 1 0 PX domain TetR_C_5 PF08360.6 EGC35989.1 - 2.5 8.0 9.4 44 4.0 6.5 2.1 1 1 0 1 1 1 0 QacR-like protein, C-terminal region IBR PF01485.16 EGC35990.1 - 8e-23 80.1 42.0 5.8e-13 48.5 7.7 4.6 3 1 1 4 4 4 2 IBR domain zf-RING_2 PF13639.1 EGC35990.1 - 1.7e-06 27.7 5.5 1.7e-06 27.7 3.8 3.6 2 1 1 3 3 3 1 Ring finger domain zf-RING_5 PF14634.1 EGC35990.1 - 5.1e-05 22.9 6.0 5.1e-05 22.9 4.1 3.7 2 1 1 3 3 3 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC35990.1 - 0.00013 21.8 7.8 0.00013 21.8 5.4 3.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC35990.1 - 0.0015 18.1 7.5 0.0015 18.1 5.2 4.0 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC35990.1 - 0.011 15.4 2.9 0.011 15.4 2.0 3.2 2 1 0 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EGC35990.1 - 0.016 15.1 4.4 0.016 15.1 3.1 3.6 3 1 0 3 3 3 0 FANCL C-terminal domain zf-TAZ PF02135.11 EGC35990.1 - 0.39 10.7 17.6 0.11 12.4 2.6 2.8 2 0 0 2 2 2 0 TAZ zinc finger zf-C3HC4_4 PF15227.1 EGC35990.1 - 3.2 7.7 31.7 0.079 12.8 1.8 4.1 3 1 0 3 3 3 0 zinc finger of C3HC4-type, RING ATG27 PF09451.5 EGC35991.1 - 0.00031 20.0 0.5 0.00048 19.4 0.4 1.2 1 0 0 1 1 1 1 Autophagy-related protein 27 SpvB PF03534.8 EGC35991.1 - 0.006 15.6 0.0 0.0081 15.2 0.0 1.1 1 0 0 1 1 1 1 Salmonella virulence plasmid 65kDa B protein DUF3430 PF11912.3 EGC35991.1 - 0.081 12.7 8.8 0.19 11.5 6.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) SAM_2 PF07647.12 EGC35992.1 - 1.3e-09 37.7 0.0 3.1e-09 36.5 0.0 1.7 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC35992.1 - 2.2e-09 37.3 0.0 4.3e-09 36.4 0.0 1.5 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) EGF_2 PF07974.8 EGC35993.1 - 0.13 12.4 10.4 0.37 11.0 7.2 1.8 1 0 0 1 1 1 0 EGF-like domain RCC1 PF00415.13 EGC35994.1 - 2.3e-88 290.2 15.2 4.2e-16 58.9 0.1 9.0 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC35994.1 - 6.7e-35 117.9 29.6 7.2e-09 35.0 0.4 7.9 7 1 0 7 7 7 6 Regulator of chromosome condensation (RCC1) repeat Connexin_CCC PF10582.4 EGC35995.1 - 2.9 7.7 8.6 12 5.7 0.9 2.8 2 0 0 2 2 2 0 Gap junction channel protein cysteine-rich domain Aldedh PF00171.17 EGC35996.1 - 9e-103 344.0 0.0 1.1e-102 343.7 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family CDV3 PF15359.1 EGC35998.1 - 0.42 10.6 4.6 0.58 10.2 3.2 1.3 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 Peptidase_M1 PF01433.15 EGC35999.1 - 9.8e-113 377.1 4.5 1e-112 377.0 2.1 1.8 2 0 0 2 2 2 1 Peptidase family M1 ERAP1_C PF11838.3 EGC35999.1 - 7.8e-39 133.8 0.8 2.3e-38 132.2 0.1 2.1 3 0 0 3 3 3 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGC35999.1 - 1.9e-17 63.4 0.3 3.6e-17 62.6 0.2 1.4 1 0 0 1 1 1 1 Peptidase MA superfamily Erf4 PF10256.4 EGC36000.1 - 0.00013 21.8 0.7 0.0036 17.1 0.0 2.3 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family SNARE_assoc PF09335.6 EGC36000.1 - 0.0081 16.3 0.2 0.015 15.4 0.1 1.4 1 1 0 1 1 1 1 SNARE associated Golgi protein RE_CfrBI PF09516.5 EGC36000.1 - 0.0088 14.9 0.1 0.012 14.4 0.1 1.1 1 0 0 1 1 1 1 CfrBI restriction endonuclease Claudin_2 PF13903.1 EGC36000.1 - 0.011 15.3 2.0 0.013 15.2 0.0 1.9 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction Reprolysin_5 PF13688.1 EGC36000.1 - 0.035 14.0 0.4 0.049 13.5 0.3 1.2 1 0 0 1 1 1 0 Metallo-peptidase family M12 SDF PF00375.13 EGC36000.1 - 0.052 12.3 1.0 0.067 11.9 0.7 1.1 1 0 0 1 1 1 0 Sodium:dicarboxylate symporter family DUF1426 PF07234.6 EGC36000.1 - 0.14 11.9 2.4 0.17 11.6 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1426) DUF3671 PF12420.3 EGC36000.1 - 0.32 10.9 3.8 0.58 10.1 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function Aminotran_3 PF00202.16 EGC36001.1 - 1.5e-102 342.9 0.0 1.8e-102 342.7 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Aminotran_1_2 PF00155.16 EGC36001.1 - 0.00023 20.2 0.0 0.00037 19.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGC36001.1 - 0.0015 17.3 0.0 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGC36001.1 - 0.046 12.8 0.1 0.13 11.3 0.0 1.7 1 1 0 1 1 1 0 Beta-eliminating lyase Oxidored_q5_N PF01059.12 EGC36002.1 - 0.53 10.1 7.3 0.96 9.3 5.1 1.4 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase chain 4, amino terminus DUF1027 PF06265.6 EGC36003.1 - 0.035 13.9 0.5 1.1 9.1 0.1 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1027) RP-C_C PF11800.3 EGC36003.1 - 0.24 11.0 1.2 0.34 10.5 0.9 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Exonuc_VII_L PF02601.10 EGC36003.1 - 8.2 5.5 11.1 2.3 7.3 5.5 1.5 2 0 0 2 2 2 0 Exonuclease VII, large subunit DCP1 PF06058.8 EGC36004.1 - 3.6e-36 123.9 0.5 5.9e-36 123.2 0.4 1.3 1 0 0 1 1 1 1 Dcp1-like decapping family PAT1 PF09770.4 EGC36004.1 - 0.96 7.6 37.4 1.2 7.2 25.9 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 LigB PF02900.13 EGC36006.1 - 8.1e-46 156.1 0.0 1e-45 155.8 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase Bystin PF05291.6 EGC36007.1 - 1.8e-123 411.2 0.4 1.8e-123 411.2 0.3 1.7 2 0 0 2 2 2 1 Bystin HA2 PF04408.18 EGC36008.1 - 2.2e-24 85.3 0.2 2.2e-24 85.3 0.2 4.1 3 1 0 3 3 3 1 Helicase associated domain (HA2) OB_NTP_bind PF07717.11 EGC36008.1 - 2.3e-16 59.6 0.1 2.3e-16 59.6 0.1 2.9 2 1 0 2 2 2 1 Oligonucleotide/oligosaccharide-binding (OB)-fold Helicase_C PF00271.26 EGC36008.1 - 6.2e-12 45.2 0.0 2.8e-11 43.1 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain FtsK_SpoIIIE PF01580.13 EGC36008.1 - 0.0022 17.4 0.3 0.29 10.6 0.0 2.7 2 0 0 2 2 2 1 FtsK/SpoIIIE family AAA_22 PF13401.1 EGC36008.1 - 0.02 15.0 0.9 0.086 12.9 0.0 2.6 2 1 0 2 2 2 0 AAA domain PEPcase PF00311.12 EGC36009.1 - 9.5e-278 923.3 0.0 1.2e-277 923.0 0.0 1.1 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase PEPcase_2 PF14010.1 EGC36009.1 - 0.00049 18.5 0.0 0.0013 17.1 0.0 1.6 1 0 0 1 1 1 1 Phosphoenolpyruvate carboxylase DUF4286 PF14114.1 EGC36010.1 - 1.7e-19 69.8 0.0 2.4e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF4286) CBM_21 PF03370.8 EGC36010.1 - 0.099 12.6 0.1 0.17 11.8 0.0 1.4 1 1 0 1 1 1 0 Putative phosphatase regulatory subunit LMBR1 PF04791.11 EGC36011.1 - 1.5 7.3 9.5 0.23 9.9 1.7 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein Gti1_Pac2 PF09729.4 EGC36011.1 - 9.4 6.0 12.7 1.7 8.4 0.2 2.6 2 1 1 3 3 3 0 Gti1/Pac2 family CHU_C PF13585.1 EGC36012.1 - 1.7 8.5 6.8 0.91 9.4 2.1 2.3 2 0 0 2 2 2 0 C-terminal domain of CHU protein family MoCF_biosynth PF00994.19 EGC36013.1 - 1.8e-52 176.5 0.4 7.8e-26 90.1 0.0 2.5 2 0 0 2 2 2 2 Probable molybdopterin binding domain MoeA_N PF03453.12 EGC36013.1 - 4.7e-45 152.8 0.5 7.4e-45 152.2 0.1 1.5 2 0 0 2 2 2 1 MoeA N-terminal region (domain I and II) MoeA_C PF03454.10 EGC36013.1 - 7e-15 54.7 0.0 1.9e-14 53.3 0.0 1.8 1 0 0 1 1 1 1 MoeA C-terminal region (domain IV) LIM PF00412.17 EGC36014.1 - 1.2e-11 44.4 10.3 2e-11 43.8 7.2 1.3 1 0 0 1 1 1 1 LIM domain TDH PF03347.8 EGC36014.1 - 0.1 12.1 0.1 0.24 10.9 0.0 1.6 2 0 0 2 2 2 0 Vibrio thermostable direct hemolysin MFS_1 PF07690.11 EGC36015.1 - 1.6e-28 99.4 11.5 1.2e-24 86.7 1.1 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGC36015.1 - 2.4e-16 59.2 1.4 2.4e-16 59.2 0.9 2.6 3 0 0 3 3 3 1 MFS_1 like family Nuc_H_symport PF03825.11 EGC36015.1 - 1.3e-11 43.9 25.4 4.7e-11 42.0 7.0 2.2 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.14 EGC36015.1 - 2.2e-07 29.7 9.1 2.2e-07 29.7 6.3 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter DUF4517 PF15006.1 EGC36016.1 - 2.8 7.7 12.5 0.18 11.6 3.0 2.1 1 1 0 2 2 2 0 Domain of unknown function (DUF4517) Mit_KHE1 PF10173.4 EGC36016.1 - 5.9 6.6 12.7 7.4 6.3 8.8 1.2 1 0 0 1 1 1 0 Mitochondrial K+-H+ exchange-related PI3_PI4_kinase PF00454.22 EGC36017.1 - 7.4e-38 130.3 2.9 1.1e-37 129.7 0.0 2.7 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGC36017.1 - 0.00021 20.5 0.2 0.00058 19.0 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) OTU PF02338.14 EGC36018.1 - 4.7e-14 53.0 0.1 6.4e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 OTU-like cysteine protease FTCD_N PF07837.7 EGC36019.1 - 5.5e-77 257.3 0.0 8.9e-77 256.6 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase domain, N-terminal subdomain FTCD_C PF04961.7 EGC36019.1 - 3.3e-57 192.9 0.0 5.2e-57 192.2 0.0 1.3 1 0 0 1 1 1 1 Formiminotransferase-cyclodeaminase FTCD PF02971.9 EGC36019.1 - 2.2e-56 189.5 0.0 3.9e-56 188.7 0.0 1.4 1 0 0 1 1 1 1 Formiminotransferase domain Hypoth_Ymh PF09509.5 EGC36019.1 - 0.062 12.9 0.0 0.14 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (Hypoth_ymh) RNB PF00773.14 EGC36020.1 - 7.3e-14 51.7 9.9 7.3e-14 51.7 6.8 4.3 2 2 1 3 3 3 1 RNB domain YgbB PF02542.11 EGC36020.1 - 0.99 9.2 4.7 0.43 10.3 0.4 2.3 2 0 0 2 2 2 0 YgbB family EspA PF03433.8 EGC36021.1 - 0.096 12.1 0.7 0.13 11.6 0.5 1.2 1 0 0 1 1 1 0 EspA-like secreted protein PARG_cat PF05028.9 EGC36021.1 - 0.11 11.7 2.0 0.12 11.6 1.4 1.0 1 0 0 1 1 1 0 Poly (ADP-ribose) glycohydrolase (PARG) CH PF00307.26 EGC36022.1 - 7.2e-25 87.1 10.8 8.1e-19 67.6 0.1 3.8 3 1 1 4 4 4 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC36022.1 - 1.1e-11 44.2 0.1 4.3e-11 42.3 0.1 2.2 1 0 0 1 1 1 1 CAMSAP CH domain WEMBL PF05701.6 EGC36022.1 - 0.1 11.0 36.7 0.15 10.5 25.4 1.1 1 0 0 1 1 1 0 Weak chloroplast movement under blue light Syntaxin-6_N PF09177.6 EGC36022.1 - 0.13 12.7 34.1 0.23 11.8 6.1 3.0 1 1 2 3 3 3 0 Syntaxin 6, N-terminal Atg14 PF10186.4 EGC36022.1 - 0.63 8.9 40.2 0.087 11.7 12.2 2.3 1 1 1 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Sipho_Gp157 PF05565.6 EGC36022.1 - 1.2 8.6 29.9 0.84 9.2 2.0 3.3 1 1 2 3 3 3 0 Siphovirus Gp157 DUF4407 PF14362.1 EGC36022.1 - 1.4 7.7 30.5 0.018 14.0 10.3 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4407) Kinetocho_Slk19 PF12709.2 EGC36022.1 - 1.9 8.6 35.8 1.2 9.2 2.1 4.8 2 2 2 4 4 4 0 Central kinetochore-associated DUF4239 PF14023.1 EGC36022.1 - 2.3 7.5 15.3 0.81 9.0 2.5 2.9 1 1 3 4 4 4 0 Protein of unknown function (DUF4239) LOH1CR12 PF10158.4 EGC36022.1 - 2.9 7.6 15.3 7.5 6.3 2.0 2.5 1 1 1 2 2 2 0 Tumour suppressor protein DUF745 PF05335.8 EGC36022.1 - 4.2 6.8 29.5 0.084 12.3 2.8 3.1 1 1 2 3 3 3 0 Protein of unknown function (DUF745) ACR_tran PF00873.14 EGC36022.1 - 6.8 3.9 11.4 2.6 5.3 6.4 1.4 1 1 0 1 1 1 0 AcrB/AcrD/AcrF family CPSase_L_D2 PF02786.12 EGC36023.1 - 2.7e-76 255.5 0.0 4.5e-76 254.8 0.0 1.4 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_L_chain PF00289.17 EGC36023.1 - 2.4e-44 149.9 0.0 5.5e-44 148.7 0.0 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, N-terminal domain Biotin_carb_C PF02785.14 EGC36023.1 - 3e-36 123.6 0.0 7.4e-36 122.3 0.0 1.7 1 0 0 1 1 1 1 Biotin carboxylase C-terminal domain Biotin_lipoyl PF00364.17 EGC36023.1 - 1.3e-16 59.9 2.8 5.2e-16 58.0 1.4 2.5 2 0 0 2 2 2 1 Biotin-requiring enzyme ATP-grasp_4 PF13535.1 EGC36023.1 - 2.1e-13 50.4 0.0 6.9e-13 48.7 0.0 1.8 2 0 0 2 2 2 1 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGC36023.1 - 4.2e-12 45.8 0.0 1e-11 44.6 0.0 1.6 1 0 0 1 1 1 1 D-ala D-ala ligase C-terminus ATPgrasp_Ter PF15632.1 EGC36023.1 - 4.2e-12 45.4 0.0 1.3e-11 43.8 0.0 1.7 1 1 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon ATP-grasp PF02222.17 EGC36023.1 - 5.2e-11 42.1 0.4 1.3e-10 40.9 0.0 1.9 3 0 0 3 3 3 1 ATP-grasp domain Biotin_lipoyl_2 PF13533.1 EGC36023.1 - 1.1e-07 31.3 2.8 4.9e-05 22.8 0.0 3.0 2 1 1 3 3 3 2 Biotin-lipoyl like ATP-grasp_3 PF02655.9 EGC36023.1 - 2.4e-05 24.2 0.0 5e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 ATP-grasp domain RnfC_N PF13375.1 EGC36023.1 - 2.7e-05 23.7 0.3 0.00046 19.8 0.1 2.9 3 0 0 3 3 3 1 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EGC36023.1 - 3.1e-05 24.2 1.7 0.085 13.2 0.0 3.5 4 0 0 4 4 4 2 HlyD family secretion protein RimK PF08443.6 EGC36023.1 - 0.00036 20.0 0.0 0.0027 17.2 0.0 2.1 1 1 0 1 1 1 1 RimK-like ATP-grasp domain GARS_A PF01071.14 EGC36023.1 - 0.0024 17.4 0.0 0.005 16.4 0.0 1.6 1 1 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain HlyD PF00529.15 EGC36023.1 - 0.0045 16.3 0.0 0.011 15.0 0.0 1.7 2 0 0 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 EGC36023.1 - 0.011 15.4 0.1 0.029 14.0 0.1 1.7 1 0 0 1 1 1 0 Glycine cleavage H-protein SCP2 PF02036.12 EGC36023.1 - 0.058 13.6 0.0 0.17 12.1 0.0 1.8 1 0 0 1 1 1 0 SCP-2 sterol transfer family GDC-P PF02347.11 EGC36024.1 - 3.1e-192 638.9 0.1 4.6e-179 595.5 0.0 3.1 3 0 0 3 3 3 3 Glycine cleavage system P-protein Aminotran_5 PF00266.14 EGC36024.1 - 6.4e-05 21.8 0.2 0.00056 18.7 0.1 2.2 2 0 0 2 2 2 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGC36024.1 - 0.0018 17.4 0.0 0.0048 16.0 0.0 1.7 2 0 0 2 2 2 1 Beta-eliminating lyase Aminotran_1_2 PF00155.16 EGC36025.1 - 1.1e-59 202.2 0.0 1.2e-59 202.0 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Cys_Met_Meta_PP PF01053.15 EGC36025.1 - 9.2e-05 20.8 0.1 0.00018 19.8 0.1 1.4 1 1 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGC36025.1 - 0.0033 16.6 0.0 0.0042 16.2 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Aminotran_5 PF00266.14 EGC36025.1 - 0.024 13.3 0.1 0.092 11.4 0.0 1.8 2 0 0 2 2 2 0 Aminotransferase class-V DUF816 PF05674.7 EGC36026.1 - 0.66 9.6 7.9 0.49 10.0 0.4 2.8 1 1 2 3 3 3 0 Baculovirus protein of unknown function (DUF816) ING PF12998.2 EGC36026.1 - 1.2 9.4 9.8 13 6.1 3.2 2.6 1 1 1 2 2 2 0 Inhibitor of growth proteins N-terminal histone-binding DUF4200 PF13863.1 EGC36026.1 - 1.3 9.0 9.1 1.2 9.1 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4200) zf-DHHC PF01529.15 EGC36027.1 - 7.7e-31 106.8 9.4 7.7e-31 106.8 6.5 2.9 2 2 0 2 2 2 1 DHHC palmitoyltransferase DUF4637 PF15470.1 EGC36027.1 - 0.0038 16.8 0.7 0.0038 16.8 0.5 1.7 1 1 1 2 2 2 1 Domain of unknown function (DUF4637) EPL1 PF10513.4 EGC36028.1 - 5.2e-22 78.8 2.6 5.2e-22 78.8 1.8 5.5 2 1 0 2 2 2 1 Enhancer of polycomb-like Response_reg PF00072.19 EGC36029.1 - 6.4e-18 64.8 0.0 1.7e-17 63.4 0.0 1.7 1 0 0 1 1 1 1 Response regulator receiver domain LRR_6 PF13516.1 EGC36029.1 - 4.5e-08 32.3 46.1 0.088 12.9 0.0 10.9 11 0 0 11 11 11 6 Leucine Rich repeat LRR_4 PF12799.2 EGC36029.1 - 0.012 15.2 2.2 0.012 15.2 1.5 8.1 5 2 4 9 9 9 0 Leucine Rich repeats (2 copies) KH_1 PF00013.24 EGC36030.1 - 2.8e-05 23.6 1.0 2.8e-05 23.6 0.7 2.2 2 0 0 2 2 2 1 KH domain p450 PF00067.17 EGC36032.1 - 5.1e-89 298.9 0.1 5.9e-89 298.7 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF3861 PF12977.2 EGC36032.1 - 0.055 13.5 0.1 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3861) IMS PF00817.15 EGC36033.1 - 0.099 12.4 0.0 0.21 11.3 0.0 1.4 1 0 0 1 1 1 0 impB/mucB/samB family Pyr_redox_2 PF07992.9 EGC36034.1 - 6.7e-22 78.3 0.0 1.4e-21 77.2 0.0 1.7 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC36034.1 - 1e-10 41.8 0.0 1.1e-09 38.5 0.0 2.7 2 1 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase EF-hand_5 PF13202.1 EGC36034.1 - 1.2e-10 40.2 11.5 2.9e-05 23.2 0.9 2.6 2 0 0 2 2 2 2 EF hand EF-hand_1 PF00036.27 EGC36034.1 - 1.2e-10 39.8 12.6 1.8e-05 23.6 1.4 2.9 3 0 0 3 3 3 2 EF hand EF-hand_6 PF13405.1 EGC36034.1 - 4.9e-10 38.4 5.5 0.00013 21.5 0.9 2.8 2 0 0 2 2 2 2 EF-hand domain EF-hand_8 PF13833.1 EGC36034.1 - 5.3e-09 35.5 7.5 9.3e-05 21.9 0.2 2.6 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_7 PF13499.1 EGC36034.1 - 5.6e-09 36.0 3.4 2.7e-08 33.8 2.4 2.2 1 1 0 1 1 1 1 EF-hand domain pair Pyr_redox_3 PF13738.1 EGC36034.1 - 0.0094 16.0 0.0 0.12 12.4 0.0 2.6 2 1 1 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase SPARC_Ca_bdg PF10591.4 EGC36034.1 - 0.065 13.2 3.4 0.074 13.0 0.1 2.6 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region DENN PF02141.16 EGC36035.1 - 1.6e-30 106.1 1.2 8.1e-30 103.9 0.8 2.3 1 1 0 1 1 1 1 DENN (AEX-3) domain uDENN PF03456.13 EGC36035.1 - 3.4e-07 30.1 0.7 1.4e-06 28.1 0.5 2.2 1 1 0 1 1 1 1 uDENN domain FNIP PF05725.7 EGC36036.1 - 1.8e-11 43.8 75.9 2.2e-06 27.5 0.3 10.1 10 3 0 11 11 11 6 FNIP Repeat FNIP PF05725.7 EGC36037.1 - 6.7e-10 38.7 18.4 1.2e-05 25.1 0.8 10.4 9 2 2 11 11 11 6 FNIP Repeat PWWP PF00855.12 EGC36038.1 - 1.1e-09 38.2 1.4 1.1e-09 38.2 1.0 3.3 3 1 0 3 3 3 1 PWWP domain Sec1 PF00995.18 EGC36039.1 - 1.3e-147 492.9 13.1 1.4e-147 492.7 9.0 1.0 1 0 0 1 1 1 1 Sec1 family HSBP1 PF06825.7 EGC36039.1 - 0.075 12.6 4.0 0.052 13.1 1.0 2.0 2 0 0 2 2 2 0 Heat shock factor binding protein 1 GARS_A PF01071.14 EGC36041.1 - 3.3e-75 251.9 0.0 6.5e-75 250.9 0.0 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain GARS_N PF02844.10 EGC36041.1 - 1.2e-32 112.3 0.2 3.7e-32 110.7 0.0 2.0 2 0 0 2 2 1 1 Phosphoribosylglycinamide synthetase, N domain AIRS_C PF02769.17 EGC36041.1 - 1.4e-29 103.1 0.0 4.6e-29 101.4 0.0 1.9 2 0 0 2 2 2 1 AIR synthase related protein, C-terminal domain GARS_C PF02843.11 EGC36041.1 - 8.4e-29 99.6 0.0 2e-28 98.4 0.0 1.7 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, C domain AIRS PF00586.19 EGC36041.1 - 1.1e-17 64.0 0.9 4.4e-17 62.0 0.7 2.2 1 0 0 1 1 1 1 AIR synthase related protein, N-terminal domain ATP-grasp_4 PF13535.1 EGC36041.1 - 2.6e-09 37.0 0.0 1.1e-07 31.7 0.0 2.4 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGC36041.1 - 6.3e-08 31.7 0.0 1.8e-07 30.2 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp in the biosynthetic pathway with Ter operon RimK PF08443.6 EGC36041.1 - 2.3e-06 27.2 0.2 3.6e-05 23.3 0.0 2.3 2 0 0 2 2 2 1 RimK-like ATP-grasp domain ATP-grasp PF02222.17 EGC36041.1 - 6e-06 25.7 0.0 1.2e-05 24.7 0.0 1.4 1 0 0 1 1 1 1 ATP-grasp domain CPSase_L_D2 PF02786.12 EGC36041.1 - 3.8e-05 23.0 0.0 0.00011 21.5 0.0 1.8 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase L chain, ATP binding domain ATP-grasp_3 PF02655.9 EGC36041.1 - 0.00063 19.6 0.0 0.002 18.0 0.0 1.8 1 0 0 1 1 1 1 ATP-grasp domain WD40 PF00400.27 EGC36042.1 - 4.7e-26 89.6 14.7 1.1e-08 34.5 0.1 6.8 6 1 0 6 6 6 6 WD domain, G-beta repeat F-box-like PF12937.2 EGC36042.1 - 4.1e-11 42.4 0.0 7.8e-11 41.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC36042.1 - 4e-07 29.5 0.0 7.6e-07 28.6 0.0 1.5 1 0 0 1 1 1 1 F-box domain BBS2_Mid PF14783.1 EGC36042.1 - 0.029 14.1 4.1 5 6.9 0.0 4.4 4 1 1 5 5 5 0 Ciliary BBSome complex subunit 2, middle region SET PF00856.23 EGC36043.1 - 5.9e-13 49.4 0.2 6e-08 33.1 0.1 2.6 3 0 0 3 3 3 2 SET domain Rubis-subs-bind PF09273.6 EGC36043.1 - 2.5e-07 30.6 0.1 6.8e-07 29.2 0.1 1.7 1 0 0 1 1 1 1 Rubisco LSMT substrate-binding EF-hand_1 PF00036.27 EGC36044.1 - 5.6e-13 47.1 0.9 2.1e-05 23.5 0.2 2.1 2 0 0 2 2 2 2 EF hand EF-hand_6 PF13405.1 EGC36044.1 - 1.3e-11 43.3 0.6 2.2e-06 27.0 0.1 2.1 2 0 0 2 2 2 2 EF-hand domain EF-hand_7 PF13499.1 EGC36044.1 - 7.3e-09 35.6 0.1 9.6e-09 35.2 0.1 1.1 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_5 PF13202.1 EGC36044.1 - 5.7e-08 31.7 0.8 0.00095 18.4 0.1 2.3 2 0 0 2 2 2 2 EF hand EF-hand_8 PF13833.1 EGC36044.1 - 1.4e-07 31.0 0.1 2.3e-07 30.3 0.0 1.4 1 1 1 2 2 2 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC36044.1 - 0.0051 16.8 0.0 0.0057 16.6 0.0 1.1 1 0 0 1 1 1 1 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGC36044.1 - 0.082 12.8 0.0 0.11 12.3 0.0 1.2 1 0 0 1 1 1 0 EF-hand domain Glycos_transf_1 PF00534.15 EGC36045.1 - 5.6e-26 90.9 0.0 5.6e-26 90.9 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_2 PF00535.21 EGC36045.1 - 1.2e-23 83.6 0.0 9.6e-23 80.6 0.0 2.5 2 0 0 2 2 2 1 Glycosyl transferase family 2 DUF563 PF04577.9 EGC36045.1 - 2.8e-22 79.6 0.2 8.7e-22 78.0 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF563) Glyco_trans_1_4 PF13692.1 EGC36045.1 - 1.5e-10 41.3 0.0 3.4e-10 40.1 0.0 1.6 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_tranf_2_3 PF13641.1 EGC36045.1 - 7e-10 39.0 0.0 1.7e-09 37.8 0.0 1.6 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_trans_2_3 PF13632.1 EGC36045.1 - 0.00018 21.2 0.4 0.00073 19.3 0.3 2.0 1 1 0 1 1 1 1 Glycosyl transferase family group 2 Glyco_trans_1_2 PF13524.1 EGC36045.1 - 0.0032 17.7 0.0 0.0093 16.2 0.0 1.8 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_7C PF02709.9 EGC36045.1 - 0.037 13.4 0.6 0.093 12.2 0.4 1.6 1 0 0 1 1 1 0 N-terminal domain of galactosyltransferase Glyco_transf_4 PF13439.1 EGC36045.1 - 0.051 13.2 0.0 0.12 12.0 0.0 1.6 1 0 0 1 1 1 0 Glycosyltransferase Family 4 ATP-synt_8 PF00895.15 EGC36045.1 - 2.3 8.5 7.1 0.15 12.3 0.3 2.6 2 0 0 2 2 2 0 ATP synthase protein 8 Ndc1_Nup PF09531.5 EGC36046.1 - 0.42 8.9 3.9 0.57 8.5 2.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Cellulase PF00150.13 EGC36048.1 - 7.9e-29 100.7 7.8 1.1e-28 100.3 5.4 1.2 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) zf-Nse PF11789.3 EGC36049.1 - 1.6e-13 49.9 1.9 1.7e-13 49.8 0.3 1.9 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGC36049.1 - 0.00052 19.6 1.3 0.0018 17.9 0.9 2.1 1 0 0 1 1 1 1 RING-type zinc-finger SSP160 PF06933.6 EGC36049.1 - 0.006 14.6 0.8 0.0092 14.0 0.6 1.4 1 0 0 1 1 1 1 Special lobe-specific silk protein SSP160 zf-MIZ PF02891.15 EGC36049.1 - 0.023 14.1 0.3 0.023 14.1 0.2 1.9 2 0 0 2 2 2 0 MIZ/SP-RING zinc finger Ldh_1_C PF02866.13 EGC36050.1 - 3.3e-40 137.6 0.0 1.1e-39 136.0 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGC36050.1 - 4.8e-26 91.2 0.1 8.7e-26 90.4 0.1 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain Med10 PF09748.4 EGC36051.1 - 2.4e-30 104.9 5.9 2.4e-30 104.9 4.1 1.9 2 0 0 2 2 2 1 Transcription factor subunit Med10 of Mediator complex BUD22 PF09073.5 EGC36051.1 - 0.14 11.1 25.6 0.21 10.5 17.8 1.3 1 1 0 1 1 1 0 BUD22 DUF1623 PF07785.6 EGC36051.1 - 0.32 10.9 3.4 2.6 8.0 2.3 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1623) SAM_1 PF00536.25 EGC36052.1 - 0.00019 21.5 0.5 0.37 11.0 0.0 3.4 3 0 0 3 3 3 2 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC36052.1 - 0.0028 17.4 0.3 0.2 11.5 0.0 3.1 2 0 0 2 2 2 1 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EGC36052.1 - 0.018 14.7 0.1 0.13 12.0 0.0 2.4 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Secretin_N_2 PF07655.8 EGC36052.1 - 8.6 6.8 19.2 4.3 7.7 7.9 2.5 2 0 0 2 2 2 0 Secretin N-terminal domain Trypan_PARP PF05887.6 EGC36053.1 - 0.045 13.5 0.0 0.055 13.2 0.0 1.1 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) DUF2372 PF10178.4 EGC36054.1 - 0.0091 16.1 0.0 4.9 7.3 0.0 2.8 2 0 0 2 2 2 2 Uncharacterised conserved protein (DUF2372) DUF498 PF04430.9 EGC36054.1 - 0.032 13.7 3.4 3.7 7.1 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF498/DUF598) zf-C2H2_7 PF15269.1 EGC36054.1 - 0.43 10.4 4.1 23 4.9 0.0 3.6 4 0 0 4 4 4 0 Zinc-finger DUF1312 PF07009.6 EGC36054.1 - 9 6.1 8.7 0.71 9.7 2.1 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1312) FNIP PF05725.7 EGC36055.1 - 1.1e-15 57.3 34.3 1.7e-09 37.4 0.9 6.5 4 2 3 7 7 7 5 FNIP Repeat LRR_8 PF13855.1 EGC36055.1 - 0.00012 21.7 4.9 0.0084 15.8 0.1 4.0 3 1 0 3 3 3 1 Leucine rich repeat Ribosomal_L7Ae PF01248.21 EGC36056.1 - 7.9e-26 89.4 1.6 9.9e-26 89.0 1.1 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family Antimicrobial19 PF08225.6 EGC36056.1 - 0.41 10.0 1.8 0.46 9.9 0.1 1.9 2 0 0 2 2 2 0 Pseudin antimicrobial peptide LRR_6 PF13516.1 EGC36059.1 - 1.4e-08 33.9 86.8 0.16 12.0 1.8 14.6 14 0 0 14 14 14 10 Leucine Rich repeat F-box-like PF12937.2 EGC36059.1 - 0.0095 15.6 0.0 0.028 14.1 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC36059.1 - 0.0099 15.5 0.0 0.04 13.5 0.0 2.1 1 0 0 1 1 1 1 F-box domain CBM49 PF09478.5 EGC36060.1 - 4.4e-16 58.7 0.2 6.2e-16 58.2 0.2 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PepSY_TM_3 PF13706.1 EGC36060.1 - 0.37 10.2 1.7 0.57 9.6 1.2 1.3 1 0 0 1 1 1 0 PepSY-associated TM helix CBM49 PF09478.5 EGC36061.1 - 6.2e-19 67.8 0.1 8.4e-19 67.4 0.1 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Pep_deformylase PF01327.16 EGC36062.1 - 1.1e-46 158.0 0.0 1.4e-46 157.7 0.0 1.1 1 0 0 1 1 1 1 Polypeptide deformylase MtN3_slv PF03083.11 EGC36063.1 - 2.6e-34 116.9 14.4 5.8e-17 61.3 1.3 2.2 2 0 0 2 2 2 2 Sugar efflux transporter for intercellular exchange BNR PF02012.15 EGC36064.1 - 3.8e-08 31.9 22.1 0.066 13.0 0.1 7.9 7 0 0 7 7 7 5 BNR/Asp-box repeat Gmad1 PF10647.4 EGC36064.1 - 0.035 13.5 0.2 0.76 9.1 0.0 2.7 3 0 0 3 3 3 0 Lipoprotein LpqB beta-propeller domain 4HBT PF03061.17 EGC36065.1 - 1.6e-13 50.5 0.0 2.2e-13 50.0 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily 4HBT_3 PF13622.1 EGC36065.1 - 0.0033 17.1 0.0 0.0044 16.8 0.0 1.2 1 0 0 1 1 1 1 Thioesterase-like superfamily Rcd1 PF04078.8 EGC36066.1 - 2.1e-94 315.2 2.5 2.4e-94 315.0 1.8 1.0 1 0 0 1 1 1 1 Cell differentiation family, Rcd1-like FPL PF09758.4 EGC36066.1 - 0.002 17.8 3.9 0.0025 17.5 0.5 2.4 3 1 0 3 3 3 1 Uncharacterised conserved protein DEAD PF00270.24 EGC36067.1 - 9e-41 139.1 2.5 9e-41 139.1 1.7 2.1 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC36067.1 - 7.7e-22 76.9 0.1 4e-13 49.0 0.0 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain ResIII PF04851.10 EGC36067.1 - 2.2e-07 30.8 0.1 2.2e-07 30.8 0.0 3.0 3 0 0 3 3 3 2 Type III restriction enzyme, res subunit DUF3072 PF11272.3 EGC36067.1 - 0.0089 15.6 0.2 0.021 14.4 0.2 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3072) AAA_22 PF13401.1 EGC36067.1 - 0.39 10.8 3.8 0.57 10.3 1.0 2.5 2 1 0 2 2 2 0 AAA domain RasGAP PF00616.14 EGC36068.1 - 9.2e-19 67.8 4.9 9.2e-19 67.8 3.4 3.2 4 0 0 4 4 4 1 GTPase-activator protein for Ras-like GTPase LRR_6 PF13516.1 EGC36068.1 - 8.6e-10 37.6 43.2 0.0027 17.5 0.3 12.0 12 0 0 12 12 12 4 Leucine Rich repeat LRR_4 PF12799.2 EGC36068.1 - 0.0012 18.4 4.6 0.0012 18.4 3.2 8.1 7 3 3 11 11 11 3 Leucine Rich repeats (2 copies) DUF4187 PF13821.1 EGC36068.1 - 0.93 9.1 2.6 1.6 8.4 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4187) LRR_1 PF00560.28 EGC36068.1 - 2.7 8.3 28.0 3.6 7.9 0.1 9.4 9 2 0 9 9 9 0 Leucine Rich Repeat Erg28 PF03694.8 EGC36072.1 - 3.1e-15 56.1 4.9 3.6e-15 55.9 3.4 1.1 1 0 0 1 1 1 1 Erg28 like protein DUF3169 PF11368.3 EGC36072.1 - 0.025 13.7 1.5 0.092 11.9 1.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3169) ArfGap PF01412.13 EGC36073.1 - 3.9e-38 129.8 0.0 3.9e-38 129.8 0.0 2.8 3 0 0 3 3 3 1 Putative GTPase activating protein for Arf Ank_2 PF12796.2 EGC36073.1 - 3.6e-17 62.4 1.8 1.7e-11 44.2 0.1 2.9 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36073.1 - 1.1e-14 53.3 4.8 1.9e-05 24.2 0.1 5.0 5 0 0 5 5 5 4 Ankyrin repeat PH PF00169.24 EGC36073.1 - 2.6e-14 53.2 0.1 2.6e-14 53.2 0.1 2.2 2 1 0 2 2 2 1 PH domain Ank_5 PF13857.1 EGC36073.1 - 1.4e-11 44.2 0.9 1.4e-07 31.4 0.3 4.5 2 1 3 5 5 5 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC36073.1 - 1.3e-09 38.2 5.9 2.9e-05 24.4 0.0 4.5 3 1 1 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36073.1 - 3.8e-07 29.7 0.9 0.084 13.1 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat PH_8 PF15409.1 EGC36073.1 - 0.00016 21.7 0.0 0.00058 19.8 0.0 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EGC36073.1 - 0.00038 20.6 1.0 0.00038 20.6 0.7 3.4 3 1 0 3 3 3 1 Pleckstrin homology domain HAUS-augmin3 PF14932.1 EGC36073.1 - 6.9 5.7 26.8 0.056 12.6 1.7 3.0 2 1 1 3 3 3 0 HAUS augmin-like complex subunit 3 PX PF00787.19 EGC36074.1 - 1.1e-08 34.8 0.3 1.3e-08 34.6 0.2 1.1 1 0 0 1 1 1 1 PX domain Aldose_epim PF01263.15 EGC36075.1 - 7.3e-41 140.2 0.8 8.3e-41 140.0 0.5 1.0 1 0 0 1 1 1 1 Aldose 1-epimerase EF-hand_7 PF13499.1 EGC36076.1 - 3.9e-07 30.0 1.9 0.018 15.1 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC36076.1 - 1.7e-06 27.3 2.8 0.0096 15.7 0.0 4.1 4 0 0 4 4 4 2 EF-hand domain EF-hand_1 PF00036.27 EGC36076.1 - 8e-06 24.8 0.2 0.042 13.1 0.0 4.2 4 0 0 4 4 4 1 EF hand EF-hand_5 PF13202.1 EGC36076.1 - 0.019 14.2 0.8 22 4.6 0.0 3.7 4 0 0 4 4 4 0 EF hand DUF3637 PF12337.3 EGC36076.1 - 0.11 12.4 0.1 14 5.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3637) Amdo_NSP PF12475.3 EGC36076.1 - 0.16 11.8 0.9 0.64 9.9 0.1 2.3 3 0 0 3 3 3 0 Amdovirus non-structural protein zf-RING_2 PF13639.1 EGC36077.1 - 3.1e-11 42.9 6.8 5.4e-11 42.1 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC36077.1 - 3.1e-09 36.3 8.7 5.2e-09 35.6 6.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36077.1 - 2.2e-08 33.9 11.1 4e-08 33.1 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC36077.1 - 2.3e-08 33.5 12.0 4.7e-08 32.5 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC36077.1 - 9.7e-08 31.6 10.1 1.9e-07 30.6 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC36077.1 - 2.1e-05 24.2 8.1 5.4e-05 22.9 5.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC36077.1 - 0.00015 21.8 4.7 0.00015 21.8 3.2 2.0 2 0 0 2 2 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGC36077.1 - 0.0032 17.0 8.5 0.0068 15.9 5.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC36077.1 - 0.0094 15.7 3.4 0.0094 15.7 2.3 1.9 2 0 0 2 2 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC36077.1 - 0.016 14.9 7.0 0.07 12.8 4.8 2.2 1 1 0 1 1 1 0 RING-type zinc-finger OppC_N PF12911.2 EGC36077.1 - 0.13 11.6 0.2 0.13 11.6 0.2 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C zf-RING_6 PF14835.1 EGC36077.1 - 0.21 11.4 5.1 0.46 10.3 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein CAF-1_p150 PF11600.3 EGC36077.1 - 2.2 7.6 62.9 0.038 13.3 28.3 2.1 1 1 1 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal OATP PF03137.15 EGC36077.1 - 3.5 5.5 7.7 0.17 9.9 1.0 2.0 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Pyr_redox_3 PF13738.1 EGC36077.1 - 3.6 7.5 6.0 5.6 6.9 4.2 1.2 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase TFIIA PF03153.8 EGC36077.1 - 5.5 6.7 34.4 8.9 6.0 23.8 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Methyltransf_10 PF05971.7 EGC36078.1 - 2.9e-29 102.1 3.7 3.9e-23 82.0 0.0 3.1 1 1 2 3 3 3 2 Protein of unknown function (DUF890) PrmA PF06325.8 EGC36078.1 - 8.3e-06 25.1 0.2 2e-05 23.8 0.0 1.7 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_18 PF12847.2 EGC36078.1 - 2.4e-05 24.8 0.0 4.4e-05 24.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC36078.1 - 3.7e-05 23.1 0.0 0.00095 18.5 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC36078.1 - 3.8e-05 23.6 0.0 6.1e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGC36078.1 - 0.00061 19.4 0.5 0.0009 18.8 0.0 1.6 2 0 0 2 2 2 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EGC36078.1 - 0.0013 18.3 6.0 0.0081 15.7 4.2 2.3 1 1 0 1 1 1 1 Methyltransferase domain UPF0020 PF01170.13 EGC36078.1 - 0.0037 16.8 0.0 0.015 14.8 0.0 1.9 2 1 0 2 2 2 1 Putative RNA methylase family UPF0020 SAP30_Sin3_bdg PF13867.1 EGC36078.1 - 0.073 12.9 0.1 0.17 11.7 0.1 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Methyltransf_11 PF08241.7 EGC36078.1 - 0.099 13.1 0.0 0.22 12.0 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36078.1 - 0.48 10.9 0.0 0.48 10.9 0.0 2.7 2 2 0 2 2 2 0 Methyltransferase domain DUF1700 PF08006.6 EGC36078.1 - 0.59 9.4 5.3 1.1 8.5 0.5 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1700) Epimerase PF01370.16 EGC36079.1 - 1.5e-54 184.9 0.0 1.9e-54 184.6 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Epimerase_Csub PF13950.1 EGC36079.1 - 5.2e-30 103.1 0.7 9.5e-30 102.3 0.5 1.5 1 0 0 1 1 1 1 UDP-glucose 4-epimerase C-term subunit 3Beta_HSD PF01073.14 EGC36079.1 - 5.8e-18 64.5 0.1 5.2e-17 61.4 0.0 1.9 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGC36079.1 - 1.6e-17 63.3 0.0 1.3e-16 60.3 0.0 2.2 2 1 0 2 2 2 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC36079.1 - 1.3e-11 44.6 0.0 2e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase RmlD_sub_bind PF04321.12 EGC36079.1 - 8.3e-11 41.2 0.0 2.1e-10 40.0 0.0 1.6 2 0 0 2 2 2 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGC36079.1 - 1.6e-09 37.9 0.0 2.5e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding KR PF08659.5 EGC36079.1 - 3.4e-09 36.6 0.0 6.7e-09 35.6 0.0 1.4 1 1 0 1 1 1 1 KR domain NAD_binding_4 PF07993.7 EGC36079.1 - 1.2e-08 34.1 0.0 4.2e-07 29.1 0.0 2.2 1 1 0 1 1 1 1 Male sterility protein NmrA PF05368.8 EGC36079.1 - 0.03 13.5 0.0 0.063 12.5 0.0 1.6 2 0 0 2 2 2 0 NmrA-like family DapB_N PF01113.15 EGC36079.1 - 0.059 13.3 0.1 0.098 12.5 0.0 1.4 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGC36079.1 - 0.065 13.5 0.0 1.2 9.4 0.0 2.5 3 0 0 3 3 3 0 Semialdehyde dehydrogenase, NAD binding domain adh_short PF00106.20 EGC36080.1 - 2.4e-21 76.3 0.0 3.1e-21 76.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36080.1 - 8.2e-10 38.8 0.0 1.1e-09 38.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36080.1 - 9.7e-05 22.0 0.0 0.00013 21.6 0.0 1.2 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGC36080.1 - 0.0013 17.7 0.1 0.0037 16.2 0.0 1.7 2 0 0 2 2 2 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGC36080.1 - 0.0065 16.5 0.0 0.0099 15.8 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC36080.1 - 0.01 15.2 0.2 0.032 13.6 0.1 1.7 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family DUF3236 PF11576.3 EGC36080.1 - 0.037 13.4 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) 3HCDH_N PF02737.13 EGC36080.1 - 0.14 11.8 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Ibs_toxin PF13956.1 EGC36081.1 - 4.6 7.1 8.2 11 5.9 5.7 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system Guanylate_cyc PF00211.15 EGC36082.1 - 6.7e-103 341.7 2.5 5e-51 172.6 0.3 2.4 2 0 0 2 2 2 2 Adenylate and Guanylate cyclase catalytic domain DUF1510 PF07423.6 EGC36082.1 - 0.91 8.8 41.2 7.1 5.9 0.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) IncA PF04156.9 EGC36082.1 - 3.7 7.1 23.4 0.043 13.4 0.9 2.7 2 0 0 2 2 2 0 IncA protein Hira PF07569.6 EGC36084.1 - 5.1e-46 156.6 3.9 1.5e-45 155.0 2.7 1.9 1 0 0 1 1 1 1 TUP1-like enhancer of split WD40 PF00400.27 EGC36084.1 - 1.1e-38 129.7 27.9 3.8e-12 45.5 0.9 7.8 8 0 0 8 8 8 6 WD domain, G-beta repeat HIRA_B PF09453.5 EGC36084.1 - 5.4e-06 25.8 0.5 1.7e-05 24.2 0.4 1.9 1 0 0 1 1 1 1 HIRA B motif PD40 PF07676.7 EGC36084.1 - 0.001 18.6 16.6 0.6 9.8 0.1 6.5 7 0 0 7 7 7 3 WD40-like Beta Propeller Repeat Zip PF02535.17 EGC36084.1 - 0.058 12.3 2.2 0.087 11.8 1.6 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Epimerase PF01370.16 EGC36085.1 - 6.5e-22 78.1 0.0 8.3e-22 77.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC36085.1 - 5.3e-13 48.3 0.3 4.1e-12 45.4 0.2 1.9 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGC36085.1 - 1.1e-11 44.2 0.1 1.7e-11 43.5 0.1 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NAD_binding_10 PF13460.1 EGC36085.1 - 4.6e-09 36.5 0.1 7.7e-09 35.8 0.0 1.4 1 1 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC36085.1 - 3.2e-05 22.9 0.2 0.0004 19.3 0.1 2.1 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGC36085.1 - 0.00032 19.6 0.3 0.00058 18.8 0.2 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC36085.1 - 0.00037 20.4 0.0 0.00052 19.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGC36085.1 - 0.001 18.3 0.2 0.0018 17.5 0.2 1.4 1 1 0 1 1 1 1 NmrA-like family Saccharop_dh PF03435.13 EGC36085.1 - 0.013 14.5 0.1 0.031 13.2 0.0 1.7 2 0 0 2 2 2 0 Saccharopine dehydrogenase KR PF08659.5 EGC36085.1 - 0.02 14.5 0.0 0.03 14.0 0.0 1.3 1 0 0 1 1 1 0 KR domain DUF1731 PF08338.6 EGC36085.1 - 0.078 12.4 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF1731) PASTA PF03793.14 EGC36085.1 - 0.086 12.4 0.0 0.25 11.0 0.0 1.8 1 0 0 1 1 1 0 PASTA domain DDE_Tnp_4 PF13359.1 EGC36086.1 - 5.1e-15 55.4 0.0 1e-14 54.4 0.0 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease PA14 PF07691.7 EGC36088.1 - 3.9e-15 55.7 0.2 6.8e-15 54.9 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC36088.1 - 0.00012 21.8 4.6 0.00012 21.8 3.2 10.9 11 2 1 12 12 12 2 Dictyostelium (slime mold) repeat Integrin_b_cyt PF08725.6 EGC36088.1 - 0.19 11.1 2.3 0.25 10.7 0.2 2.1 2 0 0 2 2 2 0 Integrin beta cytoplasmic domain Mnd1 PF03962.10 EGC36089.1 - 0.0037 16.9 4.5 0.0058 16.3 3.1 1.3 1 0 0 1 1 1 1 Mnd1 family Rsd_AlgQ PF04353.8 EGC36089.1 - 0.033 13.9 0.5 0.07 12.8 0.3 1.5 1 0 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ Na_K-ATPase PF00287.13 EGC36089.1 - 0.1 11.3 3.9 0.13 10.9 2.7 1.2 1 0 0 1 1 1 0 Sodium / potassium ATPase beta chain IncA PF04156.9 EGC36089.1 - 0.44 10.1 6.9 0.63 9.6 4.8 1.1 1 0 0 1 1 1 0 IncA protein DUF904 PF06005.7 EGC36089.1 - 0.62 10.3 7.9 71 3.7 5.5 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF904) BLOC1_2 PF10046.4 EGC36089.1 - 0.95 9.6 13.7 0.17 12.0 4.2 2.1 1 1 1 2 2 2 0 Biogenesis of lysosome-related organelles complex-1 subunit 2 DUF1640 PF07798.6 EGC36089.1 - 0.97 9.4 5.2 2 8.4 3.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1640) bZIP_1 PF00170.16 EGC36089.1 - 4.6 7.2 10.4 3 7.8 1.1 3.1 1 1 2 3 3 3 0 bZIP transcription factor Ank_3 PF13606.1 EGC36090.1 - 0.0026 17.8 0.5 2.3 8.7 0.0 2.6 2 1 0 2 2 2 2 Ankyrin repeat DUF2119 PF09892.4 EGC36090.1 - 0.0037 16.5 1.3 0.075 12.2 0.1 2.0 1 1 1 2 2 2 1 Uncharacterized protein conserved in archaea (DUF2119) PPR_1 PF12854.2 EGC36090.1 - 0.016 14.6 0.7 5.4 6.5 0.0 2.3 2 0 0 2 2 2 0 PPR repeat Ank PF00023.25 EGC36090.1 - 0.021 14.6 0.0 5.8 6.9 0.0 2.4 2 0 0 2 2 2 0 Ankyrin repeat DUF354 PF04007.7 EGC36090.1 - 0.035 12.9 3.7 1 8.1 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF354) Ank_2 PF12796.2 EGC36090.1 - 0.037 14.3 0.2 0.066 13.5 0.1 1.4 1 1 0 1 1 1 0 Ankyrin repeats (3 copies) Nop16 PF09420.5 EGC36090.1 - 0.06 13.4 0.5 9.7 6.2 0.0 2.1 2 0 0 2 2 2 0 Ribosome biogenesis protein Nop16 Phage_connect_1 PF05135.8 EGC36090.1 - 0.061 13.4 1.1 0.08 13.1 0.7 1.2 1 0 0 1 1 1 0 Phage gp6-like head-tail connector protein TFIID-31kDa PF02291.10 EGC36090.1 - 0.062 13.0 0.0 0.13 12.0 0.0 1.6 1 1 1 2 2 2 0 Transcription initiation factor IID, 31kD subunit ComFB PF10719.4 EGC36090.1 - 0.09 12.5 0.6 6.4 6.6 0.1 2.1 2 0 0 2 2 2 0 Late competence development protein ComFB DUF2281 PF10047.4 EGC36090.1 - 0.12 12.6 0.6 7.1 7.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2281) CheC PF04509.7 EGC36090.1 - 0.2 11.4 1.5 7.2 6.4 0.1 2.2 2 0 0 2 2 2 0 CheC-like family RPAP1_C PF08620.5 EGC36091.1 - 7.2e-22 77.0 0.2 4.4e-21 74.4 0.1 2.5 2 0 0 2 2 2 1 RPAP1-like, C-terminal RPAP1_N PF08621.5 EGC36091.1 - 5.9e-09 35.3 2.9 1.7e-08 33.8 2.0 1.9 1 0 0 1 1 1 1 RPAP1-like, N-terminal UQ_con PF00179.21 EGC36092.1 - 5.2e-44 149.0 0.4 4.7e-43 145.9 0.1 2.3 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 EGC36092.1 - 4e-17 62.8 0.0 7.6e-17 61.9 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Rad60-SLD PF11976.3 EGC36092.1 - 4.8e-07 29.3 0.2 2.1e-06 27.3 0.1 2.2 2 1 0 2 2 2 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGC36092.1 - 2.4e-05 23.6 0.1 7.6e-05 22.0 0.0 1.8 1 0 0 1 1 1 1 Ubiquitin family VWA PF00092.23 EGC36092.1 - 5.7e-05 22.9 0.3 0.00019 21.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain Prok-E2_B PF14461.1 EGC36092.1 - 0.0031 17.2 0.0 0.0061 16.3 0.0 1.5 1 0 0 1 1 1 1 Prokaryotic E2 family B VWA_3 PF13768.1 EGC36092.1 - 0.0032 17.1 0.0 0.018 14.7 0.0 2.0 2 0 0 2 2 2 1 von Willebrand factor type A domain YukD PF08817.5 EGC36092.1 - 0.0035 17.8 0.0 0.0091 16.5 0.0 1.8 1 0 0 1 1 1 1 WXG100 protein secretion system (Wss), protein YukD TUG-UBL1 PF11470.3 EGC36092.1 - 0.056 13.3 0.0 0.46 10.4 0.0 2.3 2 0 0 2 2 2 0 GLUT4 regulating protein TUG RasGEF PF00617.14 EGC36093.1 - 9.2e-62 208.1 4.8 9.2e-62 208.1 3.3 2.4 4 0 0 4 4 4 1 RasGEF domain RasGEF_N PF00618.15 EGC36093.1 - 3.7e-17 62.3 0.9 3.7e-17 62.3 0.6 3.1 3 1 0 3 3 3 1 RasGEF N-terminal motif Kelch_1 PF01344.20 EGC36094.1 - 1.4e-21 75.7 1.4 2.8e-09 36.3 0.2 3.1 3 0 0 3 3 3 2 Kelch motif Kelch_4 PF13418.1 EGC36094.1 - 1.7e-20 72.4 0.1 3.5e-06 26.6 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC36094.1 - 1.4e-17 63.0 1.8 4.9e-06 26.4 0.1 3.1 3 0 0 3 3 3 3 Kelch motif Kelch_3 PF13415.1 EGC36094.1 - 1.7e-16 59.8 0.2 9.2e-06 25.6 0.0 3.1 3 0 0 3 3 3 3 Galactose oxidase, central domain Kelch_2 PF07646.10 EGC36094.1 - 6.3e-11 41.5 0.0 0.0011 18.6 0.0 3.2 3 0 0 3 3 3 3 Kelch motif Kelch_5 PF13854.1 EGC36094.1 - 7.1e-07 29.0 2.7 0.00019 21.3 0.2 3.3 3 1 0 3 3 3 1 Kelch motif Rax2 PF12768.2 EGC36094.1 - 8.8e-07 28.4 0.3 2.5e-05 23.6 0.4 2.0 2 0 0 2 2 2 1 Cortical protein marker for cell polarity RWP-RK PF02042.10 EGC36095.1 - 3.8e-26 90.6 0.1 3.8e-26 90.6 0.1 1.8 2 0 0 2 2 2 1 RWP-RK domain HlyIII PF03006.15 EGC36096.1 - 1e-62 211.4 15.3 1.6e-62 210.8 10.6 1.3 1 0 0 1 1 1 1 Haemolysin-III related Barstar PF01337.13 EGC36097.1 - 1.9e-06 27.6 0.5 9.1e-06 25.4 0.1 1.9 1 1 1 2 2 2 1 Barstar (barnase inhibitor) DUF4320 PF14208.1 EGC36097.1 - 0.074 13.0 0.4 0.11 12.4 0.3 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4320) DUF2603 PF10788.4 EGC36098.1 - 0.063 13.0 0.2 0.081 12.6 0.1 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF2603) Cystatin PF00031.16 EGC36099.1 - 7.1e-06 26.0 0.1 7.2e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 Cystatin domain Cystatin PF00031.16 EGC36100.1 - 2.5e-08 33.9 1.8 2.8e-08 33.7 1.2 1.2 1 0 0 1 1 1 1 Cystatin domain EABR PF12180.3 EGC36100.1 - 0.061 12.6 0.0 0.11 11.9 0.0 1.3 1 0 0 1 1 1 0 TSG101 and ALIX binding domain of CEP55 ABC_membrane PF00664.18 EGC36101.1 - 1.3e-70 238.0 36.0 3.2e-36 125.1 7.1 2.8 3 0 0 3 3 3 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC36101.1 - 1.8e-49 167.5 0.3 1.2e-27 96.8 0.0 2.7 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC36101.1 - 5.2e-09 35.6 5.8 0.017 14.3 0.1 4.3 2 2 1 4 4 4 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EGC36101.1 - 3e-08 33.6 0.7 0.028 14.3 0.1 3.8 3 0 0 3 3 3 2 50S ribosome-binding GTPase Miro PF08477.8 EGC36101.1 - 1.8e-06 28.4 1.3 0.15 12.5 0.0 4.1 4 0 0 4 4 4 2 Miro-like protein AAA_16 PF13191.1 EGC36101.1 - 5e-06 26.6 0.2 0.012 15.6 0.0 2.7 3 0 0 3 3 2 2 AAA ATPase domain AAA_29 PF13555.1 EGC36101.1 - 2.6e-05 23.6 0.5 0.2 11.2 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGC36101.1 - 0.0003 20.6 0.4 0.2 11.4 0.1 3.5 3 0 0 3 3 3 1 Dynamin family DUF258 PF03193.11 EGC36101.1 - 0.00032 19.9 0.7 0.28 10.3 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function, DUF258 GTP_EFTU PF00009.22 EGC36101.1 - 0.00074 19.0 0.1 0.23 10.8 0.0 2.5 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_17 PF13207.1 EGC36101.1 - 0.0012 19.6 0.0 0.68 10.7 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC36101.1 - 0.003 16.9 0.1 0.4 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC36101.1 - 0.0056 16.9 0.0 1.6 9.0 0.0 2.9 2 0 0 2 2 2 1 AAA domain ArgK PF03308.11 EGC36101.1 - 0.0064 15.3 0.6 0.82 8.3 0.0 2.2 2 0 0 2 2 2 1 ArgK protein AAA_22 PF13401.1 EGC36101.1 - 0.019 15.1 0.5 8.2 6.5 0.0 2.9 2 1 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGC36101.1 - 0.025 14.0 0.1 7.4 5.9 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family MobB PF03205.9 EGC36101.1 - 0.028 14.1 2.0 3.5 7.3 0.2 3.0 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF4258 PF14076.1 EGC36101.1 - 0.073 13.0 0.2 12 6.0 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4258) AAA_33 PF13671.1 EGC36101.1 - 0.081 12.7 0.0 2.2 8.1 0.0 2.4 2 0 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGC36101.1 - 0.14 11.2 1.6 4 6.4 0.0 2.3 2 0 0 2 2 2 0 Zeta toxin CDC45 PF02724.9 EGC36101.1 - 0.52 8.2 5.8 0.79 7.6 4.0 1.2 1 0 0 1 1 1 0 CDC45-like protein DUF87 PF01935.12 EGC36101.1 - 2.5 7.8 10.3 0.5 10.1 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function DUF87 Vinculin PF01044.14 EGC36102.1 - 4.2e-05 21.7 1.4 5.2e-05 21.4 0.9 1.1 1 0 0 1 1 1 1 Vinculin family Sigma70_ner PF04546.8 EGC36102.1 - 0.023 14.2 4.2 0.018 14.6 2.0 1.5 1 1 1 2 2 2 0 Sigma-70, non-essential region TMPIT PF07851.8 EGC36102.1 - 0.16 11.0 1.5 0.38 9.7 0.5 1.9 1 1 1 2 2 2 0 TMPIT-like protein 60KD_IMP PF02096.15 EGC36103.1 - 1.1e-30 106.7 1.3 1.8e-30 106.1 0.9 1.3 1 0 0 1 1 1 1 60Kd inner membrane protein ABC2_membrane_2 PF12679.2 EGC36104.1 - 0.0083 15.0 12.5 0.091 11.6 0.5 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein E1-E2_ATPase PF00122.15 EGC36104.1 - 0.013 14.5 0.5 0.013 14.5 0.3 1.6 2 0 0 2 2 2 0 E1-E2 ATPase DUF4131 PF13567.1 EGC36104.1 - 0.061 12.7 6.7 0.22 10.9 1.5 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF4131) BatD PF13584.1 EGC36104.1 - 0.078 11.5 0.5 0.88 8.0 0.1 2.1 2 0 0 2 2 2 0 Oxygen tolerance DUF2275 PF10039.4 EGC36104.1 - 0.16 11.8 0.2 0.31 10.9 0.1 1.4 1 0 0 1 1 1 0 Predicted integral membrane protein (DUF2275) OppC_N PF12911.2 EGC36104.1 - 0.2 11.0 9.1 14 5.1 0.6 4.3 4 0 0 4 4 4 0 N-terminal TM domain of oligopeptide transport permease C ATP-synt_8 PF00895.15 EGC36104.1 - 0.32 11.2 15.4 1.2 9.3 0.7 3.6 3 0 0 3 3 3 0 ATP synthase protein 8 Pex14_N PF04695.8 EGC36105.1 - 0.0089 16.0 2.5 0.02 14.9 1.7 1.6 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Menin PF05053.8 EGC36105.1 - 0.056 11.6 3.8 0.066 11.3 2.6 1.1 1 0 0 1 1 1 0 Menin HCO3_cotransp PF00955.16 EGC36105.1 - 0.22 10.1 3.8 0.33 9.5 2.6 1.2 1 0 0 1 1 1 0 HCO3- transporter family TRP PF06011.7 EGC36105.1 - 7.2 5.0 10.4 0.065 11.7 1.9 1.5 2 0 0 2 2 2 0 Transient receptor potential (TRP) ion channel Tim54 PF11711.3 EGC36105.1 - 9.1 4.7 7.9 14 4.1 5.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 OPT PF03169.10 EGC36107.1 - 0.045 12.1 0.1 0.068 11.6 0.1 1.3 1 0 0 1 1 1 0 OPT oligopeptide transporter protein Arif-1 PF06770.6 EGC36108.1 - 0.17 11.2 0.1 0.17 11.2 0.1 2.0 1 1 1 2 2 2 0 Actin-rearrangement-inducing factor (Arif-1) DUF1049 PF06305.6 EGC36108.1 - 0.24 10.9 0.1 0.24 10.9 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) DUF4149 PF13664.1 EGC36108.1 - 0.61 10.1 13.5 3 7.9 0.8 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4149) Nucleoplasmin PF03066.10 EGC36109.1 - 0.51 9.8 11.4 0.031 13.7 2.1 2.4 2 0 0 2 2 2 0 Nucleoplasmin FNIP PF05725.7 EGC36110.1 - 1e-63 211.0 38.5 4.8e-16 58.4 3.2 5.1 4 1 1 5 5 5 5 FNIP Repeat DUF1769 PF08588.5 EGC36110.1 - 0.011 15.6 7.5 0.42 10.5 0.1 4.5 1 1 4 5 5 5 0 Protein of unknown function (DUF1769) LRR_6 PF13516.1 EGC36110.1 - 0.42 10.8 18.3 39 4.7 0.1 7.7 9 0 0 9 9 9 0 Leucine Rich repeat LRR_5 PF13306.1 EGC36110.1 - 0.85 9.3 4.1 3.5 7.3 0.3 2.8 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) MAPKK1_Int PF08923.5 EGC36111.1 - 1.7e-34 118.0 5.2 2e-34 117.7 3.6 1.0 1 0 0 1 1 1 1 Mitogen-activated protein kinase kinase 1 interacting Erf4 PF10256.4 EGC36112.1 - 2.7e-09 36.9 4.8 2.4e-06 27.4 0.0 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF1049 PF06305.6 EGC36112.1 - 0.00019 20.8 0.9 0.26 10.7 0.1 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) Tetraspannin PF00335.15 EGC36112.1 - 1.7 7.8 9.2 4.6 6.4 0.5 2.3 2 0 0 2 2 2 0 Tetraspanin family HD PF01966.17 EGC36114.1 - 2.1e-10 40.6 0.1 4.1e-10 39.7 0.1 1.4 1 0 0 1 1 1 1 HD domain Methyltransf_16 PF10294.4 EGC36115.1 - 8.8e-24 83.8 1.5 6.4e-23 81.0 1.1 2.0 1 1 0 1 1 1 1 Putative methyltransferase GidB PF02527.10 EGC36115.1 - 1.4e-06 27.5 0.4 2.8e-06 26.5 0.3 1.4 1 0 0 1 1 1 1 rRNA small subunit methyltransferase G Methyltransf_18 PF12847.2 EGC36115.1 - 3.2e-06 27.6 0.0 4.4e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC36115.1 - 1.4e-05 24.5 0.0 2.2e-05 23.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGC36115.1 - 2.6e-05 23.8 0.3 3.8e-05 23.3 0.2 1.5 1 1 0 1 1 1 1 Methyltransferase domain TRM PF02005.11 EGC36115.1 - 0.00041 19.3 0.1 0.0006 18.8 0.0 1.3 1 0 0 1 1 1 1 N2,N2-dimethylguanosine tRNA methyltransferase PCMT PF01135.14 EGC36115.1 - 0.0038 16.8 0.0 0.0054 16.2 0.0 1.2 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGC36115.1 - 0.0064 15.6 0.5 0.015 14.3 0.3 1.7 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_12 PF08242.7 EGC36115.1 - 0.015 15.7 0.1 0.037 14.4 0.1 1.7 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36115.1 - 0.023 15.1 0.0 0.041 14.3 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGC36115.1 - 0.026 14.8 0.0 0.094 13.0 0.0 1.9 1 1 0 2 2 2 0 Methyltransferase domain RrnaAD PF00398.15 EGC36115.1 - 0.034 13.1 0.0 0.058 12.4 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA adenine dimethylase MscS_porin PF12795.2 EGC36115.1 - 0.064 12.5 0.0 0.096 11.9 0.0 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain Methyltransf_23 PF13489.1 EGC36115.1 - 0.12 12.0 0.0 0.18 11.5 0.0 1.5 1 1 0 1 1 1 0 Methyltransferase domain Met_10 PF02475.11 EGC36115.1 - 0.24 10.9 1.4 0.35 10.4 1.0 1.4 1 1 0 1 1 1 0 Met-10+ like-protein PsbI PF02532.9 EGC36117.1 - 0.12 12.0 0.1 0.18 11.4 0.1 1.3 1 0 0 1 1 1 0 Photosystem II reaction centre I protein (PSII 4.8 kDa protein) IGFBP PF00219.13 EGC36117.1 - 0.46 11.0 51.0 2.2 8.8 7.6 4.1 1 1 3 4 4 4 0 Insulin-like growth factor binding protein BBS2_Mid PF14783.1 EGC36118.1 - 2.5e-05 24.0 0.9 0.00032 20.4 0.0 3.2 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region DUF2561 PF10812.3 EGC36118.1 - 0.77 9.3 1.1 1.3 8.5 0.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2561) Zip PF02535.17 EGC36118.1 - 0.99 8.3 10.5 2 7.3 1.1 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter DUF4557 PF15101.1 EGC36118.1 - 9.8 5.9 24.9 0.17 11.7 11.5 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4557) WD40 PF00400.27 EGC36119.1 - 3.5e-20 71.0 15.3 0.00056 19.6 0.7 7.1 6 1 0 6 6 6 5 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC36119.1 - 7.6e-05 22.4 0.1 0.76 9.5 0.0 4.5 5 0 0 5 5 5 2 Ciliary BBSome complex subunit 2, middle region DUF3911 PF13050.1 EGC36119.1 - 0.011 15.8 2.1 0.011 15.8 1.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3911) Cullin PF00888.17 EGC36121.1 - 9e-185 615.5 23.7 1.4e-184 614.9 16.5 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGC36121.1 - 1.4e-28 98.5 4.7 1.4e-28 98.5 3.3 2.5 2 0 0 2 2 2 1 Cullin protein neddylation domain HbrB PF08539.6 EGC36121.1 - 0.0017 18.2 0.6 0.0094 15.8 0.4 2.4 1 1 0 1 1 1 1 HbrB-like WAC_Acf1_DNA_bd PF10537.4 EGC36121.1 - 0.031 14.4 0.4 0.13 12.4 0.3 2.1 1 0 0 1 1 1 0 ATP-utilising chromatin assembly and remodelling N-terminal Penicillinase_R PF03965.11 EGC36121.1 - 0.087 12.9 3.1 0.44 10.6 0.4 3.2 3 0 0 3 3 3 0 Penicillinase repressor Clat_adaptor_s PF01217.15 EGC36122.1 - 2.2e-38 131.1 4.5 2.5e-38 130.9 3.1 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain CAP_C PF08603.6 EGC36122.1 - 0.1 11.9 0.3 0.13 11.5 0.2 1.2 1 0 0 1 1 1 0 Adenylate cyclase associated (CAP) C terminal CwfJ_C_1 PF04677.10 EGC36123.1 - 1.5e-31 108.5 0.3 4.8e-31 106.9 0.2 1.9 1 0 0 1 1 1 1 Protein similar to CwfJ C-terminus 1 CwfJ_C_2 PF04676.9 EGC36123.1 - 4.3e-12 46.3 0.3 4.3e-12 46.3 0.2 3.1 2 1 1 3 3 3 1 Protein similar to CwfJ C-terminus 2 KTI12 PF08433.5 EGC36124.1 - 2.8e-96 321.8 0.1 3.1e-96 321.7 0.1 1.0 1 0 0 1 1 1 1 Chromatin associated protein KTI12 AAA_33 PF13671.1 EGC36124.1 - 1e-12 48.1 0.0 2.7e-12 46.7 0.0 1.7 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC36124.1 - 0.0038 16.3 0.1 0.017 14.1 0.0 2.0 1 1 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGC36124.1 - 0.01 16.6 0.0 0.021 15.6 0.0 1.6 2 0 0 2 2 2 0 AAA domain AAA_18 PF13238.1 EGC36124.1 - 0.029 14.6 0.0 0.054 13.8 0.0 1.6 1 0 0 1 1 1 0 AAA domain APS_kinase PF01583.15 EGC36124.1 - 0.029 14.0 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EGC36124.1 - 0.062 12.6 0.2 0.32 10.3 0.0 2.5 2 1 0 2 2 2 0 Thymidylate kinase DUF1285 PF06938.6 EGC36124.1 - 0.11 12.4 0.0 4.3 7.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1285) zf-TRAF PF02176.13 EGC36125.1 - 2.3e-11 43.8 27.7 4.1e-09 36.6 8.2 2.4 1 1 2 3 3 3 2 TRAF-type zinc finger KxDL PF10241.4 EGC36125.1 - 0.021 14.7 0.2 0.043 13.7 0.1 1.5 1 0 0 1 1 1 0 Uncharacterized conserved protein Utp13 PF08625.6 EGC36125.1 - 0.033 13.8 1.9 0.057 13.0 1.3 1.6 1 1 0 1 1 1 0 Utp13 specific WD40 associated domain RNHCP PF12647.2 EGC36125.1 - 0.23 11.3 8.3 1.4 8.8 0.4 2.5 1 1 1 2 2 2 0 RNHCP domain V_ATPase_I PF01496.14 EGC36125.1 - 0.75 7.5 6.2 0.88 7.3 4.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Nup54 PF13874.1 EGC36125.1 - 1.1 8.8 5.4 0.29 10.7 1.7 1.5 2 0 0 2 2 2 0 Nucleoporin complex subunit 54 DUF217 PF02697.9 EGC36125.1 - 4.7 7.5 15.0 0.17 12.1 2.6 2.9 2 1 1 3 3 3 0 Uncharacterized ACR, COG1753 BIR PF00653.16 EGC36125.1 - 7.7 7.0 9.3 27 5.2 6.4 2.1 1 1 0 1 1 1 0 Inhibitor of Apoptosis domain DZR PF12773.2 EGC36125.1 - 8.3 6.3 13.7 7.3 6.4 1.9 2.4 1 1 1 2 2 2 0 Double zinc ribbon YhhN PF07947.9 EGC36126.1 - 1.4e-41 141.9 21.7 1.4e-41 141.9 15.0 1.4 2 0 0 2 2 2 1 YhhN-like protein PDCD2_C PF04194.8 EGC36129.1 - 9.6e-26 90.3 12.1 2.6e-25 88.8 4.5 3.1 2 1 0 2 2 2 1 Programmed cell death protein 2, C-terminal putative domain zf-MYND PF01753.13 EGC36129.1 - 1.6e-07 31.0 16.6 1.6e-07 31.0 11.5 3.5 3 1 0 3 3 3 1 MYND finger Nucleoplasmin PF03066.10 EGC36129.1 - 0.19 11.2 5.1 0.34 10.4 3.6 1.4 1 0 0 1 1 1 0 Nucleoplasmin Rap_GAP PF02145.10 EGC36130.1 - 2.4e-59 199.9 0.0 3.2e-59 199.4 0.0 1.2 1 0 0 1 1 1 1 Rap/ran-GAP Ank_2 PF12796.2 EGC36131.1 - 4.1e-19 68.7 0.1 8e-19 67.7 0.1 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36131.1 - 3.5e-18 64.4 0.5 5.7e-12 44.8 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGC36131.1 - 5.3e-17 61.4 0.6 3e-09 36.8 0.1 3.0 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC36131.1 - 1e-13 51.3 0.2 1.1e-08 35.2 0.0 2.7 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36131.1 - 2.6e-12 45.7 0.4 1e-07 31.4 0.0 3.6 3 0 0 3 3 3 1 Ankyrin repeat RA PF00788.18 EGC36131.1 - 1.1e-09 38.6 0.0 2.5e-09 37.4 0.0 1.5 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Glucan_synthase PF02364.10 EGC36131.1 - 0.0094 13.8 1.2 0.013 13.4 0.9 1.0 1 0 0 1 1 1 1 1,3-beta-glucan synthase component XFP_N PF09364.5 EGC36131.1 - 0.023 13.2 0.0 0.034 12.6 0.0 1.2 1 0 0 1 1 1 0 XFP N-terminal domain DUF2098 PF09871.4 EGC36131.1 - 0.041 13.8 1.2 0.087 12.7 0.9 1.5 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2098) DUF230 PF03003.11 EGC36131.1 - 0.057 12.9 1.2 0.074 12.5 0.0 1.8 2 0 0 2 2 2 0 Poxvirus proteins of unknown function ATP-synt_E PF05680.7 EGC36131.1 - 0.08 12.9 3.1 0.15 12.0 2.1 1.4 1 0 0 1 1 1 0 ATP synthase E chain Robl_LC7 PF03259.12 EGC36132.1 - 0.0075 15.8 0.0 0.034 13.7 0.0 1.8 1 1 0 1 1 1 1 Roadblock/LC7 domain RhoGEF PF00621.15 EGC36134.1 - 2.8e-46 157.6 5.5 2.8e-46 157.6 3.8 2.7 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.26 EGC36134.1 - 2.4e-30 104.7 2.2 7.4e-14 51.7 0.8 3.2 2 0 0 2 2 2 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC36134.1 - 2.5e-05 23.8 0.1 0.005 16.4 0.0 3.2 2 0 0 2 2 2 1 CAMSAP CH domain IQ PF00612.22 EGC36134.1 - 0.00061 19.2 1.9 0.0014 18.0 1.3 1.7 1 0 0 1 1 1 1 IQ calmodulin-binding motif PH PF00169.24 EGC36134.1 - 0.0028 17.8 2.5 0.0028 17.8 1.8 2.6 3 0 0 3 3 3 1 PH domain DUF948 PF06103.6 EGC36134.1 - 2.6 7.9 16.6 3.9 7.4 0.0 4.3 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) BTB_2 PF02214.17 EGC36135.1 - 1.4e-16 60.4 0.1 6.7e-16 58.2 0.0 2.2 3 0 0 3 3 3 1 BTB/POZ domain DUF4482 PF14818.1 EGC36135.1 - 0.0062 17.2 2.0 0.011 16.4 1.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4482) Ead_Ea22 PF13935.1 EGC36135.1 - 0.0077 16.5 0.3 0.016 15.5 0.2 1.4 1 0 0 1 1 1 1 Ead/Ea22-like protein Gin PF10764.4 EGC36135.1 - 0.1 12.3 0.4 1.6 8.5 0.2 2.4 2 0 0 2 2 2 0 Inhibitor of sigma-G Gin Macoilin PF09726.4 EGC36135.1 - 1.8 6.7 10.7 2.2 6.4 7.4 1.2 1 0 0 1 1 1 0 Transmembrane protein Kelch_1 PF01344.20 EGC36136.1 - 7e-35 118.3 16.3 3.9e-16 58.3 0.3 5.6 6 0 0 6 6 6 3 Kelch motif Kelch_6 PF13964.1 EGC36136.1 - 4e-33 112.1 9.0 2.2e-11 43.4 0.1 5.0 3 2 2 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EGC36136.1 - 2.6e-15 55.4 5.7 5.4e-07 29.1 0.0 5.1 5 2 0 5 5 5 3 Kelch motif Kelch_4 PF13418.1 EGC36136.1 - 1.1e-14 53.8 6.3 2.9e-05 23.7 0.1 4.3 4 1 1 5 5 5 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC36136.1 - 2e-10 40.3 8.7 3.6e-05 23.6 0.1 4.5 5 0 0 5 5 5 3 Kelch motif Kelch_3 PF13415.1 EGC36136.1 - 7.4e-09 35.5 0.9 0.027 14.6 0.1 3.7 4 0 0 4 4 4 3 Galactose oxidase, central domain PQQ_3 PF13570.1 EGC36136.1 - 0.0085 16.3 2.1 19 5.6 0.0 3.8 4 0 0 4 4 4 0 PQQ-like domain FBA_1 PF07734.8 EGC36136.1 - 0.057 13.1 0.0 0.34 10.5 0.0 2.1 2 1 1 3 3 3 0 F-box associated Peptidase_C8 PF03569.8 EGC36137.1 - 0.081 12.2 0.1 9.1 5.5 0.0 2.7 2 1 1 3 3 3 0 Peptidase family C8 PH PF00169.24 EGC36138.1 - 6e-07 29.6 2.2 0.00012 22.2 0.1 3.3 2 0 0 2 2 2 2 PH domain PARP PF00644.15 EGC36139.1 - 2.7e-13 49.8 6.9 3.9e-12 46.0 1.5 3.1 1 1 1 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain ARID PF01388.16 EGC36140.1 - 0.011 15.5 0.8 0.011 15.5 0.6 2.2 2 1 0 2 2 2 0 ARID/BRIGHT DNA binding domain DUF2046 PF09755.4 EGC36141.1 - 4.1e-24 85.0 41.5 3.8e-21 75.2 19.7 2.4 1 1 1 2 2 2 2 Uncharacterized conserved protein H4 (DUF2046) MetW PF07021.7 EGC36141.1 - 0.042 13.2 4.8 0.44 9.8 2.3 2.3 2 0 0 2 2 2 0 Methionine biosynthesis protein MetW HpcH_HpaI PF03328.9 EGC36142.1 - 3.8e-42 143.6 0.3 1.8e-41 141.4 0.1 1.8 2 0 0 2 2 2 1 HpcH/HpaI aldolase/citrate lyase family C-C_Bond_Lyase PF15617.1 EGC36142.1 - 1.5e-17 63.5 0.3 6.9e-11 41.5 0.0 2.2 1 1 0 2 2 2 2 C-C_Bond_Lyase of the TIM-Barrel fold Mic1 PF07035.7 EGC36142.1 - 0.06 12.7 0.2 0.13 11.6 0.1 1.5 2 0 0 2 2 2 0 Colon cancer-associated protein Mic1-like CBM49 PF09478.5 EGC36143.1 - 2e-15 56.6 0.7 2.7e-15 56.2 0.5 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TILa PF12714.2 EGC36143.1 - 0.18 11.5 4.5 0.29 10.9 3.1 1.3 1 0 0 1 1 1 0 TILa domain WD40 PF00400.27 EGC36144.1 - 1.8e-10 40.2 10.5 0.00027 20.6 0.3 4.2 4 0 0 4 4 4 3 WD domain, G-beta repeat DUF2115 PF09888.4 EGC36144.1 - 0.093 12.8 4.5 1 9.4 0.8 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Rav1p_C PF12234.3 EGC36145.1 - 4.4e-88 296.0 0.2 4.4e-88 296.0 0.1 3.1 3 0 0 3 3 3 2 RAVE protein 1 C terminal WD40 PF00400.27 EGC36145.1 - 1.4e-27 94.4 32.2 4.6e-05 23.1 0.0 12.1 13 0 0 13 13 13 8 WD domain, G-beta repeat tRNA-synt_1 PF00133.17 EGC36146.1 - 5.1e-20 71.0 0.0 1.4e-12 46.4 0.0 3.2 2 1 0 2 2 2 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC36146.1 - 4.5e-12 45.9 4.1 7.4e-12 45.2 1.4 2.5 2 1 0 2 2 2 1 Anticodon-binding domain of tRNA DHHA2 PF02833.9 EGC36146.1 - 0.016 15.3 0.2 0.98 9.6 0.0 2.6 2 0 0 2 2 2 0 DHHA2 domain Chorein_N PF12624.2 EGC36147.1 - 1.5e-17 63.2 5.7 1.1e-16 60.4 1.5 3.0 1 1 1 2 2 2 2 N-terminal region of Chorein, a TM vesicle-mediated sorter CH PF00307.26 EGC36149.1 - 1e-38 131.6 11.9 6.5e-16 58.3 0.3 5.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC36149.1 - 4.4e-06 26.2 1.8 0.00017 21.1 0.1 3.3 3 0 0 3 3 3 1 CAMSAP CH domain NumbF PF06311.7 EGC36149.1 - 0.17 11.9 7.2 5 7.2 0.1 4.1 3 0 0 3 3 3 0 NUMB domain HAP1_N PF04849.8 EGC36150.1 - 3.8e-06 26.0 6.0 3.8e-06 26.0 4.2 4.0 2 2 2 4 4 4 2 HAP1 N-terminal conserved region CCDC155 PF14662.1 EGC36150.1 - 0.0067 16.0 45.8 0.011 15.3 16.9 2.7 1 1 1 2 2 2 1 Coiled-coil region of CCDC155 Alkyl_sulf_dimr PF14863.1 EGC36150.1 - 0.022 14.9 0.6 0.051 13.8 0.4 1.5 1 0 0 1 1 1 0 Alkyl sulfatase dimerisation bZIP_1 PF00170.16 EGC36150.1 - 0.55 10.2 36.6 0.17 11.8 1.3 5.1 3 1 1 4 4 4 0 bZIP transcription factor Las1 PF04031.8 EGC36151.1 - 4.1e-41 140.2 0.1 1.2e-40 138.6 0.1 1.9 1 0 0 1 1 1 1 Las1-like Adaptin_binding PF10199.4 EGC36152.1 - 2 8.6 10.2 16 5.7 7.1 2.0 1 1 0 1 1 1 0 Alpha and gamma adaptin binding protein p34 F-actin_cap_A PF01267.12 EGC36153.1 - 3.2e-83 278.9 0.5 3.8e-83 278.6 0.4 1.0 1 0 0 1 1 1 1 F-actin capping protein alpha subunit Cript PF10235.4 EGC36153.1 - 0.071 13.4 1.6 0.35 11.2 0.3 2.5 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT DUF1768 PF08719.6 EGC36154.1 - 2.2e-40 137.9 0.2 2.5e-40 137.7 0.1 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF1768) Trp_halogenase PF04820.9 EGC36155.1 - 4.5e-14 51.9 0.0 9.7e-09 34.3 0.0 2.4 1 1 1 2 2 2 2 Tryptophan halogenase DAO PF01266.19 EGC36155.1 - 0.014 14.3 0.2 0.043 12.7 0.0 1.8 2 0 0 2 2 2 0 FAD dependent oxidoreductase DUF4144 PF13642.1 EGC36155.1 - 0.069 13.4 0.1 0.23 11.7 0.0 1.9 2 0 0 2 2 2 0 protein structure with unknown function NAD_binding_9 PF13454.1 EGC36155.1 - 0.097 12.4 0.0 0.3 10.8 0.0 1.8 2 0 0 2 2 2 0 FAD-NAD(P)-binding Pyr_redox_2 PF07992.9 EGC36155.1 - 0.11 12.3 0.0 0.6 9.9 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_3 PF01494.14 EGC36155.1 - 0.15 11.0 0.1 0.86 8.5 0.1 1.9 1 1 0 1 1 1 0 FAD binding domain Nucleoplasmin PF03066.10 EGC36156.1 - 0.029 13.8 5.0 0.043 13.3 2.8 1.8 2 0 0 2 2 2 0 Nucleoplasmin Ribosomal_60s PF00428.14 EGC36156.1 - 0.15 12.4 11.4 0.37 11.2 7.9 1.7 1 1 0 1 1 1 0 60s Acidic ribosomal protein PBP1_TM PF14812.1 EGC36156.1 - 0.67 10.2 3.8 1.8 8.9 2.7 1.7 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SR-25 PF10500.4 EGC36156.1 - 1.3 8.4 16.6 0.18 11.2 7.4 2.2 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein G10 PF01125.12 EGC36157.1 - 6.8e-59 197.5 6.5 7.6e-59 197.4 4.5 1.0 1 0 0 1 1 1 1 G10 protein Catalase PF00199.14 EGC36159.1 - 6e-162 538.6 0.0 9.1e-162 538.1 0.0 1.3 1 0 0 1 1 1 1 Catalase Catalase-rel PF06628.7 EGC36159.1 - 5.2e-21 74.2 0.0 1.1e-20 73.2 0.0 1.6 1 0 0 1 1 1 1 Catalase-related immune-responsive PH PF00169.24 EGC36160.1 - 1.5e-11 44.4 0.2 4.4e-11 42.8 0.1 1.9 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC36160.1 - 0.00051 20.2 0.4 0.0022 18.1 0.3 2.2 1 0 0 1 1 1 1 Pleckstrin homology domain bPH_3 PF14470.1 EGC36160.1 - 0.26 11.5 4.6 0.74 10.1 0.1 3.3 4 0 0 4 4 4 0 Bacterial PH domain EAF PF09816.4 EGC36161.1 - 2.1e-17 63.0 0.8 2.6e-17 62.7 0.6 1.1 1 0 0 1 1 1 1 RNA polymerase II transcription elongation factor DUF3910 PF13049.1 EGC36161.1 - 0.051 13.6 0.2 0.09 12.8 0.1 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3910) ITI_HC_C PF06668.7 EGC36161.1 - 0.056 12.8 0.0 0.071 12.5 0.0 1.1 1 0 0 1 1 1 0 Inter-alpha-trypsin inhibitor heavy chain C-terminus PhoPQ_related PF10142.4 EGC36163.1 - 1.5e-111 372.4 3.9 1.7e-111 372.2 2.7 1.1 1 0 0 1 1 1 1 PhoPQ-activated pathogenicity-related protein Pkinase PF00069.20 EGC36164.1 - 3.2e-39 134.6 0.0 3.2e-39 134.6 0.0 3.5 4 0 0 4 4 4 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36164.1 - 1.6e-26 92.9 0.0 5.4e-26 91.2 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EGC36164.1 - 3.3e-08 33.4 18.0 8.4e-06 25.6 0.2 4.3 4 0 0 4 4 4 2 Ribonuclease 2-5A Mating_N PF12731.2 EGC36166.1 - 0.09 12.6 0.5 0.4 10.5 0.1 2.1 2 0 0 2 2 2 0 Mating-type protein beta 1 Dimer_Tnp_hAT PF05699.9 EGC36167.1 - 1.4e-12 47.0 0.2 1.7e-12 46.7 0.1 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Nup35_RRM PF05172.8 EGC36168.1 - 1e-10 41.2 0.1 2.2e-10 40.1 0.0 1.5 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGC36168.1 - 1.4e-07 31.1 0.0 2.1e-07 30.6 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EGC36168.1 - 0.0045 16.9 0.0 0.0063 16.4 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC36168.1 - 0.0055 16.3 0.0 0.0071 15.9 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Beta-lactamase PF00144.19 EGC36169.1 - 2.6e-50 171.3 0.0 4e-50 170.7 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase TPR_8 PF13181.1 EGC36170.1 - 0.014 15.1 0.1 0.052 13.3 0.1 2.1 1 0 0 1 1 1 0 Tetratricopeptide repeat Vps16_C PF04840.7 EGC36173.1 - 4e-83 278.9 6.1 5.8e-83 278.4 4.2 1.2 1 0 0 1 1 1 1 Vps16, C-terminal region Vps16_N PF04841.8 EGC36173.1 - 4.8e-80 269.1 0.1 7.5e-80 268.4 0.1 1.3 1 0 0 1 1 1 1 Vps16, N-terminal region DUF4404 PF14357.1 EGC36173.1 - 0.07 13.5 0.6 5.3 7.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4404) Methyltransf_PK PF05891.7 EGC36175.1 - 2.9e-73 245.7 0.1 3.7e-73 245.4 0.1 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EGC36175.1 - 3.9e-07 29.9 0.1 5.5e-07 29.4 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36175.1 - 3.4e-05 24.2 0.0 6.6e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36175.1 - 0.00017 22.0 0.0 0.00035 20.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36175.1 - 0.00023 21.6 0.0 0.00045 20.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC36175.1 - 0.00083 19.6 0.0 0.0016 18.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_2 PF00891.13 EGC36175.1 - 0.011 14.9 0.0 0.016 14.3 0.0 1.3 1 0 0 1 1 1 0 O-methyltransferase TehB PF03848.9 EGC36175.1 - 0.047 12.8 0.0 0.062 12.4 0.0 1.3 1 0 0 1 1 1 0 Tellurite resistance protein TehB FNIP_N PF14636.1 EGC36177.1 - 0.053 13.9 0.0 0.07 13.6 0.0 1.1 1 0 0 1 1 1 0 Folliculin-interacting protein N-terminus DEAD PF00270.24 EGC36178.1 - 2.3e-34 118.3 1.0 6.7e-34 116.8 0.6 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC36178.1 - 5.3e-24 83.8 0.0 2.3e-23 81.8 0.0 2.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4_3 PF13920.1 EGC36178.1 - 1.2e-13 50.5 6.2 1.2e-13 50.5 4.3 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36178.1 - 1.4e-05 25.0 9.5 1.4e-05 25.0 6.6 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Spore_coat_CotO PF14153.1 EGC36178.1 - 0.00095 18.6 9.9 0.00095 18.6 6.8 3.5 3 0 0 3 3 3 1 Spore coat protein CotO Prok-RING_4 PF14447.1 EGC36178.1 - 0.028 13.9 4.0 0.083 12.4 2.8 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 Zip PF02535.17 EGC36178.1 - 0.52 9.2 4.1 0.8 8.6 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter zf-RING_2 PF13639.1 EGC36178.1 - 1.6 8.6 13.2 0.12 12.1 5.4 2.0 2 0 0 2 2 2 0 Ring finger domain Apq12 PF12716.2 EGC36178.1 - 5.8 6.6 6.3 0.16 11.6 0.1 1.6 2 0 0 2 2 2 0 Nuclear pore assembly and biogenesis WD40 PF00400.27 EGC36179.1 - 7.9e-10 38.2 4.9 1.6e-07 30.9 0.1 3.8 4 0 0 4 4 4 2 WD domain, G-beta repeat Nup160 PF11715.3 EGC36179.1 - 0.00049 18.3 0.1 0.0015 16.7 0.0 1.7 2 0 0 2 2 2 1 Nucleoporin Nup120/160 Hira PF07569.6 EGC36179.1 - 0.36 10.0 0.1 0.36 10.0 0.0 3.3 4 0 0 4 4 4 0 TUP1-like enhancer of split Clat_adaptor_s PF01217.15 EGC36180.1 - 2.1e-08 34.0 2.1 2.4e-08 33.8 1.4 1.1 1 0 0 1 1 1 1 Clathrin adaptor complex small chain RepB-RCR_reg PF10723.4 EGC36180.1 - 0.039 13.6 0.0 0.091 12.5 0.0 1.5 1 0 0 1 1 1 0 Replication regulatory protein RepB Chromo PF00385.19 EGC36181.1 - 4.1e-10 39.1 2.1 5.1e-10 38.8 1.4 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain OTU PF02338.14 EGC36182.1 - 3.7e-11 43.6 0.3 8.8e-11 42.4 0.1 1.8 2 0 0 2 2 2 1 OTU-like cysteine protease Neur_chan_memb PF02932.11 EGC36182.1 - 0.021 14.7 1.9 0.033 14.0 1.3 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region RSN1_TM PF13967.1 EGC36182.1 - 0.11 12.0 0.1 0.22 11.1 0.0 1.5 1 0 0 1 1 1 0 Late exocytosis, associated with Golgi transport PAT1 PF09770.4 EGC36182.1 - 0.36 9.0 35.1 0.47 8.6 24.3 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 EGC36182.1 - 0.94 8.4 5.7 1.1 8.1 2.9 1.9 2 1 0 2 2 2 0 ZIP Zinc transporter Ank_2 PF12796.2 EGC36183.1 - 3.3e-29 101.0 5.2 2.2e-15 56.7 0.2 3.2 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36183.1 - 1.3e-20 72.0 0.1 1.2e-07 31.1 0.0 4.5 4 0 0 4 4 4 4 Ankyrin repeat Ank_4 PF13637.1 EGC36183.1 - 2.1e-19 69.4 2.0 4.7e-10 39.6 0.1 4.0 2 1 2 4 4 4 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC36183.1 - 5.4e-17 61.4 0.7 7.6e-10 38.7 0.1 3.6 2 2 2 4 4 4 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36183.1 - 1.4e-15 55.7 0.8 0.0045 17.1 0.0 4.6 4 0 0 4 4 4 4 Ankyrin repeat CH PF00307.26 EGC36183.1 - 5.5e-11 42.4 0.4 1.3e-10 41.2 0.3 1.6 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC36183.1 - 0.00094 18.7 0.0 0.0022 17.6 0.0 1.5 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 EGC36183.1 - 0.012 15.6 0.2 0.032 14.2 0.1 1.7 1 0 0 1 1 1 0 CDC24 Calponin Orbi_VP5 PF00901.12 EGC36183.1 - 0.034 12.3 8.4 0.053 11.7 5.8 1.2 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 V_ATPase_I PF01496.14 EGC36183.1 - 0.2 9.4 3.2 0.31 8.8 2.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family SprA-related PF12118.3 EGC36183.1 - 1.1 8.4 9.1 1.7 7.9 6.3 1.2 1 0 0 1 1 1 0 SprA-related family IncA PF04156.9 EGC36183.1 - 3.3 7.2 11.5 5.9 6.4 7.9 1.3 1 0 0 1 1 1 0 IncA protein DOMON PF03351.12 EGC36184.1 - 7.2e-23 80.8 0.3 7.2e-23 80.8 0.2 2.3 2 0 0 2 2 2 1 DOMON domain Cytochrom_B561 PF03188.11 EGC36184.1 - 7.4e-14 51.7 11.5 7.4e-14 51.7 8.0 2.1 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 OAD_gamma PF04277.8 EGC36184.1 - 0.43 10.9 0.0 0.43 10.9 0.0 2.3 2 0 0 2 2 2 0 Oxaloacetate decarboxylase, gamma chain DUF2244 PF10003.4 EGC36184.1 - 1.8 7.9 5.0 0.39 10.0 0.3 2.1 2 0 0 2 2 2 0 Integral membrane protein (DUF2244) DUF4131 PF13567.1 EGC36184.1 - 1.8 7.9 12.1 0.68 9.3 1.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4131) DUF4209 PF13910.1 EGC36186.1 - 2.1e-27 95.0 0.6 2.9e-23 81.7 0.1 2.9 2 0 0 2 2 2 2 Domain of unknown function (DUF4209) NUC153 PF08159.7 EGC36187.1 - 1.3e-07 31.0 0.5 4.1e-07 29.4 0.3 1.9 1 0 0 1 1 1 1 NUC153 domain AAA PF00004.24 EGC36188.1 - 2.3e-43 147.5 0.0 5.9e-43 146.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGC36188.1 - 1.6e-07 31.4 0.0 4.4e-07 29.9 0.0 1.7 2 0 0 2 2 1 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGC36188.1 - 4.9e-06 26.3 0.0 1.8e-05 24.5 0.0 2.1 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC36188.1 - 1.2e-05 25.4 0.1 5.8e-05 23.1 0.0 2.0 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGC36188.1 - 1.3e-05 25.3 0.1 0.00037 20.6 0.1 2.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC36188.1 - 9.9e-05 22.0 0.3 0.00033 20.3 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain AAA_17 PF13207.1 EGC36188.1 - 0.0001 23.1 0.2 0.00035 21.3 0.0 2.0 2 1 0 2 2 1 1 AAA domain RuvB_N PF05496.7 EGC36188.1 - 0.0001 21.4 0.0 0.00016 20.8 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGC36188.1 - 0.00046 19.6 0.0 0.00085 18.7 0.0 1.3 1 0 0 1 1 1 1 IstB-like ATP binding protein TIP49 PF06068.8 EGC36188.1 - 0.0011 17.7 0.0 0.0021 16.8 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus AAA_33 PF13671.1 EGC36188.1 - 0.0012 18.7 0.0 0.0027 17.5 0.0 1.5 1 0 0 1 1 1 1 AAA domain AAA_3 PF07726.6 EGC36188.1 - 0.0024 17.4 0.0 0.012 15.2 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGC36188.1 - 0.0028 17.5 0.0 0.0054 16.6 0.0 1.5 1 0 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC36188.1 - 0.0044 16.1 0.0 0.0081 15.2 0.0 1.4 1 0 0 1 1 1 1 Zeta toxin AAA_28 PF13521.1 EGC36188.1 - 0.0047 16.9 0.0 0.0093 15.9 0.0 1.5 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGC36188.1 - 0.0071 15.5 0.1 0.016 14.4 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGC36188.1 - 0.0091 15.2 0.0 0.079 12.1 0.0 2.2 2 0 0 2 2 2 1 PhoH-like protein KaiC PF06745.8 EGC36188.1 - 0.012 14.7 0.0 0.031 13.3 0.0 1.7 1 0 0 1 1 1 0 KaiC AAA_25 PF13481.1 EGC36188.1 - 0.013 14.9 0.4 0.072 12.4 0.0 2.3 2 1 1 3 3 3 0 AAA domain AAA_24 PF13479.1 EGC36188.1 - 0.015 14.9 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 AAA domain RNA_helicase PF00910.17 EGC36188.1 - 0.017 15.3 0.0 0.036 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA helicase AAA_11 PF13086.1 EGC36188.1 - 0.018 14.6 0.0 0.058 12.9 0.0 1.8 2 1 0 2 2 1 0 AAA domain AAA_18 PF13238.1 EGC36188.1 - 0.025 14.8 2.6 0.032 14.5 0.0 2.5 3 1 1 4 4 2 0 AAA domain Sigma54_activat PF00158.21 EGC36188.1 - 0.032 13.7 0.0 0.11 11.9 0.0 1.8 2 0 0 2 2 2 0 Sigma-54 interaction domain Histone PF00125.19 EGC36188.1 - 0.034 14.2 0.0 0.08 13.0 0.0 1.6 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 DUF815 PF05673.8 EGC36188.1 - 0.036 12.9 0.0 0.078 11.8 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF815) Parvo_NS1 PF01057.12 EGC36188.1 - 0.039 12.8 0.0 0.068 12.0 0.0 1.3 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 EGC36188.1 - 0.042 12.8 0.7 0.76 8.6 0.0 2.1 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) Sigma54_activ_2 PF14532.1 EGC36188.1 - 0.042 13.8 0.0 0.2 11.7 0.0 2.2 2 0 0 2 2 2 0 Sigma-54 interaction domain NACHT PF05729.7 EGC36188.1 - 0.079 12.6 0.0 0.59 9.7 0.0 2.1 2 0 0 2 2 2 0 NACHT domain ABC_tran PF00005.22 EGC36188.1 - 0.084 13.1 0.4 0.6 10.4 0.0 2.4 3 0 0 3 3 2 0 ABC transporter IncA PF04156.9 EGC36188.1 - 0.09 12.3 1.2 0.17 11.4 0.8 1.4 1 0 0 1 1 1 0 IncA protein DASH_Dad2 PF08654.5 EGC36188.1 - 0.11 12.4 2.4 0.43 10.6 0.6 2.3 2 0 0 2 2 2 0 DASH complex subunit Dad2 FlaC_arch PF05377.6 EGC36188.1 - 4.5 7.2 6.7 6.5 6.7 2.7 2.4 2 0 0 2 2 2 0 Flagella accessory protein C (FlaC) zf-U1 PF06220.7 EGC36189.1 - 3.8e-21 74.3 4.7 5.3e-21 73.8 3.2 1.2 1 0 0 1 1 1 1 U1 zinc finger zf-C2H2_jaz PF12171.3 EGC36189.1 - 0.00086 19.3 10.2 0.0093 16.0 7.1 2.2 1 1 0 1 1 1 1 Zinc-finger double-stranded RNA-binding PyrI_C PF02748.10 EGC36189.1 - 0.2 11.1 0.7 0.36 10.3 0.5 1.5 1 0 0 1 1 1 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain zf-met PF12874.2 EGC36189.1 - 0.26 11.5 5.2 6.3 7.1 3.6 2.3 1 1 0 1 1 1 0 Zinc-finger of C2H2 type Peptidase_S49 PF01343.13 EGC36190.1 - 1.1e-63 213.6 0.5 5.9e-40 136.5 0.0 2.7 3 0 0 3 3 3 2 Peptidase family S49 SDH_sah PF01972.11 EGC36190.1 - 8.1e-05 21.5 0.0 0.00015 20.6 0.0 1.4 1 0 0 1 1 1 1 Serine dehydrogenase proteinase CLP_protease PF00574.18 EGC36190.1 - 0.00016 21.4 1.3 0.05 13.2 0.5 2.6 2 0 0 2 2 2 2 Clp protease G3P_antiterm PF04309.7 EGC36190.1 - 0.0098 14.9 0.0 0.058 12.4 0.0 2.2 2 0 0 2 2 2 1 Glycerol-3-phosphate responsive antiterminator Ligase_CoA PF00549.14 EGC36190.1 - 0.084 12.4 0.1 0.28 10.7 0.0 1.9 2 0 0 2 2 2 0 CoA-ligase THF_DHG_CYH PF00763.18 EGC36190.1 - 0.13 12.3 1.3 1.2 9.1 0.1 2.7 2 1 0 2 2 2 0 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain Flavoprotein PF02441.14 EGC36191.1 - 4.3e-42 142.8 0.4 5.4e-42 142.5 0.3 1.1 1 0 0 1 1 1 1 Flavoprotein TPR_12 PF13424.1 EGC36192.1 - 5.6e-10 39.0 1.4 4.3e-07 29.7 0.1 2.0 1 1 1 2 2 2 2 Tetratricopeptide repeat RPN7 PF10602.4 EGC36192.1 - 0.0014 18.0 1.8 0.0023 17.3 1.2 1.4 1 1 0 1 1 1 1 26S proteasome subunit RPN7 TPR_7 PF13176.1 EGC36192.1 - 0.0015 18.1 0.2 0.021 14.5 0.0 2.8 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC36192.1 - 0.0036 16.9 0.8 0.024 14.2 0.1 2.3 2 1 0 2 2 2 1 TPR repeat SPO22 PF08631.5 EGC36192.1 - 0.01 14.9 0.4 0.017 14.2 0.2 1.4 1 1 0 1 1 1 0 Meiosis protein SPO22/ZIP4 like DUF2225 PF09986.4 EGC36192.1 - 0.017 14.5 0.6 0.03 13.7 0.4 1.4 1 1 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2225) SNAP PF14938.1 EGC36192.1 - 0.027 13.6 0.2 0.036 13.2 0.1 1.1 1 0 0 1 1 1 0 Soluble NSF attachment protein, SNAP PhageMin_Tail PF10145.4 EGC36192.1 - 0.047 13.3 0.2 0.068 12.8 0.1 1.2 1 0 0 1 1 1 0 Phage-related minor tail protein TPR_10 PF13374.1 EGC36192.1 - 0.059 13.3 0.0 0.13 12.2 0.0 1.6 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC36192.1 - 0.12 12.0 0.6 0.78 9.4 0.0 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat KOW PF00467.24 EGC36193.1 - 4.6e-22 76.8 24.9 2.5e-06 26.9 0.2 7.4 7 0 0 7 7 7 6 KOW motif Spt5-NGN PF03439.8 EGC36193.1 - 2.9e-17 62.1 0.0 5.6e-17 61.2 0.0 1.5 1 0 0 1 1 1 1 Early transcription elongation factor of RNA pol II, NGN section Spt5_N PF11942.3 EGC36193.1 - 0.0024 18.4 25.4 0.0024 18.4 17.6 3.1 2 0 0 2 2 2 1 Spt5 transcription elongation factor, acidic N-terminal DUF2763 PF10961.3 EGC36193.1 - 0.061 13.7 4.8 0.31 11.4 3.4 2.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2763) PCNA_N PF00705.13 EGC36194.1 - 1.9e-50 169.6 2.2 2.6e-50 169.1 1.0 1.5 2 0 0 2 2 2 1 Proliferating cell nuclear antigen, N-terminal domain PCNA_C PF02747.10 EGC36194.1 - 1.1e-47 161.1 0.3 3.5e-47 159.5 0.1 1.9 2 1 0 2 2 2 1 Proliferating cell nuclear antigen, C-terminal domain Rad1 PF02144.11 EGC36194.1 - 8.8e-10 37.8 0.9 6.7e-05 21.7 0.0 2.0 1 1 1 2 2 2 2 Repair protein Rad1/Rec1/Rad17 Rad9 PF04139.8 EGC36194.1 - 8.3e-05 21.8 0.1 9.5e-05 21.6 0.1 1.1 1 0 0 1 1 1 1 Rad9 FTP PF07504.8 EGC36194.1 - 0.025 14.0 0.0 0.065 12.7 0.0 1.7 1 0 0 1 1 1 0 Fungalysin/Thermolysin Propeptide Motif Ribosomal_L35p PF01632.14 EGC36195.1 - 0.028 14.3 0.1 0.055 13.3 0.1 1.6 1 0 0 1 1 1 0 Ribosomal protein L35 EF-hand_7 PF13499.1 EGC36196.1 - 3e-07 30.4 4.8 3.1e-06 27.2 0.4 2.3 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC36196.1 - 4.7e-06 26.0 2.6 0.0049 16.6 0.1 3.3 3 0 0 3 3 3 2 EF-hand domain EF-hand_1 PF00036.27 EGC36196.1 - 2.5e-05 23.2 6.6 0.003 16.7 0.1 3.4 3 0 0 3 3 3 2 EF hand EF_assoc_1 PF08355.7 EGC36196.1 - 0.00043 19.4 0.0 0.00073 18.7 0.0 1.4 1 0 0 1 1 1 1 EF hand associated EF-hand_like PF09279.6 EGC36196.1 - 0.0099 15.8 0.0 0.025 14.5 0.0 1.7 1 1 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_5 PF13202.1 EGC36196.1 - 1.5 8.2 7.6 11 5.5 0.0 3.6 3 1 1 4 4 4 0 EF hand FNIP PF05725.7 EGC36198.1 - 6.2e-154 499.7 82.2 2.6e-16 59.2 0.6 12.2 5 2 9 15 15 15 15 FNIP Repeat MerC PF03203.9 EGC36198.1 - 0.00084 19.6 1.6 57 4.1 0.0 6.3 2 2 7 9 9 9 1 MerC mercury resistance protein CN_hydrolase PF00795.17 EGC36199.1 - 7.6e-34 116.6 0.0 1e-33 116.2 0.0 1.2 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Glyco_hydro_97 PF10566.4 EGC36199.1 - 0.064 12.3 0.0 0.092 11.8 0.0 1.2 1 0 0 1 1 1 0 Glycoside hydrolase 97 Erf4 PF10256.4 EGC36201.1 - 8.6e-08 32.0 0.1 2e-07 30.8 0.1 1.6 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family ATP_synt_I PF03899.10 EGC36201.1 - 0.00049 20.2 0.9 0.00073 19.6 0.6 1.1 1 0 0 1 1 1 1 ATP synthase I chain Peptidase_M50B PF13398.1 EGC36201.1 - 0.012 14.9 0.6 0.017 14.5 0.4 1.1 1 0 0 1 1 1 0 Peptidase M50B-like YibE_F PF07907.6 EGC36201.1 - 0.042 13.0 0.6 0.056 12.6 0.4 1.1 1 0 0 1 1 1 0 YibE/F-like protein DUF4131 PF13567.1 EGC36201.1 - 0.05 13.0 0.0 0.067 12.5 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) Interfer-bind PF09294.5 EGC36201.1 - 0.15 12.1 2.9 0.33 11.0 1.9 1.7 1 1 0 1 1 1 0 Interferon-alpha/beta receptor, fibronectin type III DUF3267 PF11667.3 EGC36202.1 - 0.00021 21.4 1.8 0.0004 20.5 1.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF3267) LRRC37AB_C PF14914.1 EGC36203.1 - 0.09 12.2 1.6 0.19 11.1 1.0 1.6 1 1 0 1 1 1 0 LRRC37A/B like protein 1 C-terminal domain NADH_dehy_S2_C PF06444.6 EGC36203.1 - 2.6 8.4 7.5 0.38 11.0 0.7 2.4 2 0 0 2 2 2 0 NADH dehydrogenase subunit 2 C-terminus FA_FANCE PF11510.3 EGC36204.1 - 6.7e-11 41.8 1.6 1.1e-10 41.0 1.1 1.3 1 0 0 1 1 1 1 Fanconi Anaemia group E protein FANCE Asp-B-Hydro_N PF05279.6 EGC36204.1 - 0.18 11.6 7.4 0.13 12.1 0.5 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region R3H-assoc PF13902.1 EGC36204.1 - 0.63 10.0 9.0 0.044 13.7 1.4 2.6 2 1 0 2 2 2 0 R3H-associated N-terminal domain RRM_1 PF00076.17 EGC36205.1 - 1.2e-39 133.7 0.8 1.1e-15 57.0 0.0 4.6 3 1 1 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC36205.1 - 2.4e-28 97.8 0.2 1.4e-10 40.9 0.0 4.1 3 1 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC36205.1 - 9.7e-19 66.9 0.9 3.3e-07 30.0 0.0 4.1 4 0 0 4 4 4 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SprA-related PF12118.3 EGC36205.1 - 1.3e-05 24.7 34.5 1.3e-05 24.7 23.9 2.2 2 0 0 2 2 2 1 SprA-related family OB_RNB PF08206.6 EGC36205.1 - 0.085 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 Ribonuclease B OB domain Med15 PF09606.5 EGC36205.1 - 1.1 7.3 69.5 0.0066 14.7 39.4 2.0 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal TFIIA PF03153.8 EGC36205.1 - 2.4 7.9 65.8 0.53 10.1 29.6 2.2 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit CENP-T PF15511.1 EGC36205.1 - 6.9 5.7 20.1 12 4.9 14.0 1.3 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TPR_11 PF13414.1 EGC36206.1 - 2.4e-23 81.5 0.9 1.7e-07 30.7 0.0 6.2 4 2 2 6 6 6 3 TPR repeat TPR_8 PF13181.1 EGC36206.1 - 2.1e-18 64.6 2.6 0.027 14.2 0.0 9.4 9 1 1 10 10 10 4 Tetratricopeptide repeat TPR_12 PF13424.1 EGC36206.1 - 1.4e-15 56.9 0.6 0.022 14.6 0.0 7.7 5 2 5 10 10 10 5 Tetratricopeptide repeat TPR_2 PF07719.12 EGC36206.1 - 3.9e-15 54.4 0.0 0.073 13.0 0.0 8.0 9 0 0 9 9 9 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGC36206.1 - 1.8e-14 52.5 0.3 0.0026 17.3 0.0 7.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC36206.1 - 4e-11 43.0 0.4 0.053 13.8 0.0 4.9 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC36206.1 - 8.2e-11 41.5 0.0 0.8 10.5 0.0 7.1 4 1 4 8 8 8 3 Tetratricopeptide repeat Apc3 PF12895.2 EGC36206.1 - 2e-08 34.2 6.5 1 9.5 0.0 5.8 3 2 4 7 7 7 5 Anaphase-promoting complex, cyclosome, subunit 3 TPR_16 PF13432.1 EGC36206.1 - 2.5e-05 24.8 0.0 2.4 8.9 0.0 4.4 2 1 3 5 5 5 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC36206.1 - 0.00014 21.7 0.0 13 6.2 0.0 5.8 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_9 PF13371.1 EGC36206.1 - 0.00033 20.4 0.1 0.091 12.6 0.0 3.2 1 1 3 4 4 4 1 Tetratricopeptide repeat Glutaredoxin PF00462.19 EGC36206.1 - 0.0032 17.4 0.1 0.32 10.9 0.0 2.9 2 0 0 2 2 2 1 Glutaredoxin Kri1_C PF12936.2 EGC36207.1 - 5.5e-17 61.4 12.5 5.5e-17 61.4 8.7 5.6 4 2 0 4 4 4 1 KRI1-like family C-terminal Es2 PF09751.4 EGC36208.1 - 1.3e-77 262.0 23.2 1.3e-77 262.0 16.1 1.7 1 1 1 2 2 2 1 Nuclear protein Es2 Peptidase_C1 PF00112.18 EGC36209.1 - 1.1e-49 169.3 5.9 1.3e-49 169.0 4.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1_2 PF03051.10 EGC36209.1 - 0.57 8.6 2.8 0.6 8.5 0.4 1.8 2 0 0 2 2 2 0 Peptidase C1-like family Ribosomal_L6e PF01159.14 EGC36210.1 - 1.5e-39 134.5 4.2 1.5e-39 134.5 2.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L6e ROS_MUCR PF05443.6 EGC36210.1 - 0.02 14.6 2.4 2 8.1 0.3 2.5 2 1 0 2 2 2 0 ROS/MUCR transcriptional regulator protein 4HBT PF03061.17 EGC36211.1 - 1.4e-11 44.3 0.0 2.5e-07 30.7 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.17 EGC36211.1 - 0.00023 20.7 0.1 0.00076 19.0 0.1 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC36211.1 - 0.02 14.8 0.0 0.048 13.6 0.0 1.7 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Profilin PF00235.14 EGC36212.1 - 1.3e-39 135.0 1.6 1.5e-39 134.8 1.1 1.0 1 0 0 1 1 1 1 Profilin LRR_1 PF00560.28 EGC36213.1 - 0.0017 18.1 9.1 1.6 9.0 0.1 5.8 3 1 1 4 4 4 2 Leucine Rich Repeat EGF_2 PF07974.8 EGC36213.1 - 0.0087 16.2 10.7 0.0087 16.2 7.4 3.0 3 0 0 3 3 3 1 EGF-like domain LRR_6 PF13516.1 EGC36213.1 - 0.01 15.8 4.9 6.8 7.0 0.1 4.8 3 0 0 3 3 3 0 Leucine Rich repeat DUF3827 PF12877.2 EGC36213.1 - 0.018 13.1 0.7 0.026 12.6 0.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF3827) LRR_7 PF13504.1 EGC36213.1 - 0.032 14.3 1.6 11 6.6 0.0 4.2 2 0 0 2 2 2 0 Leucine rich repeat SKG6 PF08693.5 EGC36213.1 - 0.062 12.6 4.8 0.13 11.5 3.3 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain Laminin_EGF PF00053.19 EGC36213.1 - 0.098 12.5 6.1 0.31 11.0 4.2 1.8 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EGC36213.1 - 0.89 9.5 5.8 3.3 7.7 4.0 2.0 1 0 0 1 1 1 0 Alliinase EGF-like domain Ank_2 PF12796.2 EGC36214.1 - 3.5e-49 165.0 2.8 2.5e-15 56.5 0.1 5.9 1 1 3 5 5 5 5 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36214.1 - 6.5e-39 129.8 7.3 1.2e-06 27.9 0.0 9.2 8 0 0 8 8 8 8 Ankyrin repeat Ank_4 PF13637.1 EGC36214.1 - 1.8e-35 120.6 4.7 5.3e-06 26.7 0.0 7.7 5 1 2 7 7 7 7 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC36214.1 - 6.3e-33 112.0 2.1 8.9e-05 22.6 0.0 7.1 5 2 2 7 7 7 6 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36214.1 - 3.3e-20 70.1 3.9 0.021 14.9 0.0 8.5 7 0 0 7 7 7 5 Ankyrin repeat BTB PF00651.26 EGC36214.1 - 2e-19 69.5 0.0 1.2e-05 25.2 0.0 5.0 4 0 0 4 4 4 4 BTB/POZ domain FNIP PF05725.7 EGC36215.1 - 1.8e-139 453.4 61.1 4.5e-16 58.5 0.2 9.9 3 1 7 12 12 12 12 FNIP Repeat Strumpellin PF10266.4 EGC36216.1 - 0 1519.2 29.0 0 1519.1 20.1 1.0 1 0 0 1 1 1 1 Hereditary spastic paraplegia protein strumpellin BPL_LplA_LipB PF03099.14 EGC36217.1 - 7.2e-21 74.4 0.0 1.3e-20 73.6 0.0 1.4 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family Lip_prot_lig_C PF10437.4 EGC36217.1 - 2.6e-20 71.8 0.7 1.8e-19 69.1 0.2 2.5 2 1 1 3 3 3 1 Bacterial lipoate protein ligase C-terminus PRTP PF01366.13 EGC36217.1 - 0.054 11.4 0.6 0.11 10.4 0.2 1.6 2 0 0 2 2 2 0 Herpesvirus processing and transport protein ADK PF00406.17 EGC36218.1 - 3.9e-51 172.8 0.0 4.7e-51 172.6 0.0 1.0 1 0 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGC36218.1 - 6.8e-11 42.5 0.0 1.2e-10 41.7 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC36218.1 - 2.1e-10 40.6 0.0 3e-10 40.1 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC36218.1 - 4.5e-09 37.1 0.0 7.9e-09 36.3 0.0 1.3 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC36218.1 - 6.8e-07 28.5 0.0 9e-07 28.1 0.0 1.1 1 0 0 1 1 1 1 Zeta toxin Thymidylate_kin PF02223.12 EGC36218.1 - 0.00027 20.3 0.3 0.25 10.6 0.1 2.1 2 0 0 2 2 2 2 Thymidylate kinase AAA PF00004.24 EGC36218.1 - 0.0044 17.2 0.2 0.014 15.5 0.0 1.8 1 1 1 2 2 2 1 ATPase family associated with various cellular activities (AAA) dNK PF01712.14 EGC36218.1 - 0.022 14.6 0.2 0.031 14.1 0.1 1.2 1 0 0 1 1 1 0 Deoxynucleoside kinase AAA_19 PF13245.1 EGC36218.1 - 0.094 12.4 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain zf-CCHC_3 PF13917.1 EGC36219.1 - 5.2e-16 58.1 2.1 1.2e-15 56.8 1.4 1.6 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGC36219.1 - 0.51 10.3 2.3 0.89 9.6 1.6 1.4 1 0 0 1 1 1 0 Zinc knuckle GATA PF00320.22 EGC36221.1 - 9.8e-08 31.2 4.3 1.9e-07 30.3 3.0 1.5 1 0 0 1 1 1 1 GATA zinc finger GATA PF00320.22 EGC36222.1 - 0.014 14.6 6.3 0.025 13.9 4.4 1.3 1 0 0 1 1 1 0 GATA zinc finger DZR PF12773.2 EGC36225.1 - 0.01 15.6 1.9 2.5 7.9 0.4 2.0 1 1 1 2 2 2 0 Double zinc ribbon GATA PF00320.22 EGC36225.1 - 0.011 15.1 0.3 0.011 15.1 0.2 1.7 2 0 0 2 2 2 0 GATA zinc finger zf-C2H2_3 PF13878.1 EGC36225.1 - 0.037 13.5 0.9 0.054 13.0 0.0 1.7 2 0 0 2 2 2 0 zinc-finger of acetyl-transferase ESCO zf-RING_3 PF14369.1 EGC36225.1 - 0.072 13.1 0.5 7.9 6.5 0.0 2.1 2 0 0 2 2 2 0 zinc-finger OrfB_Zn_ribbon PF07282.6 EGC36225.1 - 0.86 9.3 3.5 1.5 8.5 2.0 1.8 1 1 1 2 2 2 0 Putative transposase DNA-binding domain Pkinase PF00069.20 EGC36226.1 - 2.3e-26 92.4 2.5 8.5e-26 90.6 0.5 2.3 2 1 1 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36226.1 - 1.3e-23 83.4 0.1 3.5e-21 75.4 0.0 2.2 1 1 1 2 2 2 2 Protein tyrosine kinase RIO1 PF01163.17 EGC36226.1 - 7.8e-05 22.1 0.7 0.00018 20.9 0.1 1.9 2 0 0 2 2 2 1 RIO1 family APH PF01636.18 EGC36226.1 - 0.00072 19.3 0.0 0.036 13.7 0.0 2.4 2 1 1 3 3 3 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC36226.1 - 0.0033 16.5 0.0 0.0049 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family tRNA-synt_2c PF01411.14 EGC36227.1 - 2.2e-53 181.4 0.5 9.3e-44 149.6 0.1 2.4 1 1 1 2 2 2 2 tRNA synthetases class II (A) Homeobox PF00046.24 EGC36228.1 - 4.3e-13 48.6 0.3 3e-08 33.1 0.0 2.6 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 EGC36228.1 - 1.9e-05 24.2 0.1 0.038 13.6 0.0 2.9 1 1 2 3 3 3 2 Homeobox KN domain Mucin PF01456.12 EGC36228.1 - 4 7.2 37.5 0.66 9.7 22.6 2.0 2 0 0 2 2 2 0 Mucin-like glycoprotein TBP-binding PF09247.6 EGC36231.1 - 0.14 12.3 0.3 0.28 11.4 0.2 1.4 1 0 0 1 1 1 0 TATA box-binding protein binding HMG_box PF00505.14 EGC36232.1 - 1.8e-18 66.5 2.1 3.4e-18 65.6 1.5 1.5 1 0 0 1 1 1 1 HMG (high mobility group) box HMG_box_2 PF09011.5 EGC36232.1 - 9.3e-14 51.5 3.3 1.2e-13 51.1 1.4 1.8 1 1 1 2 2 2 1 HMG-box domain YABBY PF04690.8 EGC36232.1 - 0.44 10.7 2.1 0.39 10.9 0.2 1.7 1 1 1 2 2 2 0 YABBY protein zf-H2C2_5 PF13909.1 EGC36234.1 - 0.046 13.9 1.7 0.11 12.8 1.1 1.7 1 0 0 1 1 1 0 C2H2-type zinc-finger domain DUF4484 PF14831.1 EGC36234.1 - 0.052 13.6 0.4 0.057 13.5 0.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) DUF3439 PF11921.3 EGC36234.1 - 0.11 12.2 2.5 0.19 11.4 1.8 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-C2H2 PF00096.21 EGC36234.1 - 0.15 12.4 1.2 0.33 11.3 0.8 1.7 1 0 0 1 1 1 0 Zinc finger, C2H2 type EF-1_beta_acid PF10587.4 EGC36234.1 - 1.6 8.9 5.8 3.2 7.9 4.0 1.5 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region DUF272 PF03312.10 EGC36235.1 - 0.0056 16.8 6.1 0.0081 16.3 4.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF272) SAP30_Sin3_bdg PF13867.1 EGC36235.1 - 0.02 14.7 2.7 0.042 13.7 1.8 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 FAM178 PF14816.1 EGC36235.1 - 0.022 13.4 2.8 0.028 13.1 2.0 1.3 1 0 0 1 1 1 0 Family of unknown function, FAM178 Cys_Met_Meta_PP PF01053.15 EGC36236.1 - 1.9e-26 92.2 0.1 2.3e-26 91.9 0.1 1.2 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGC36236.1 - 9.4e-07 28.1 0.1 1.3e-06 27.6 0.1 1.2 1 0 0 1 1 1 1 Aminotransferase class I and II DUF2738 PF10927.3 EGC36236.1 - 0.0029 16.6 1.2 0.0052 15.8 0.2 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF2738) LRR_4 PF12799.2 EGC36237.1 - 0.00032 20.2 5.2 0.00032 20.2 3.6 2.9 1 1 1 2 2 2 1 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC36237.1 - 0.069 12.9 9.9 0.88 9.3 1.7 2.7 2 1 1 3 3 3 0 Leucine rich repeat LRR_7 PF13504.1 EGC36237.1 - 0.076 13.2 1.4 7.6 7.2 0.1 3.7 3 2 0 3 3 3 0 Leucine rich repeat Lamp PF01299.12 EGC36237.1 - 0.13 11.3 4.5 0.19 10.8 3.1 1.2 1 0 0 1 1 1 0 Lysosome-associated membrane glycoprotein (Lamp) LRR_6 PF13516.1 EGC36237.1 - 1.4 9.2 12.1 0.3 11.2 0.6 4.1 4 0 0 4 4 4 0 Leucine Rich repeat GATA PF00320.22 EGC36238.1 - 0.11 11.8 11.5 0.048 13.0 6.2 1.7 2 0 0 2 2 2 0 GATA zinc finger Peptidase_C74 PF12387.3 EGC36238.1 - 2.3 7.3 7.7 5.2 6.1 0.0 2.1 1 1 1 2 2 2 0 Pestivirus NS2 peptidase Nitr_red_alph_N PF14710.1 EGC36240.1 - 0.77 10.0 5.5 17 5.7 0.1 3.0 3 0 0 3 3 3 0 Respiratory nitrate reductase alpha N-terminal FUSC PF04632.7 EGC36240.1 - 2.2 6.6 9.4 2.6 6.3 6.5 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family PSCyt1 PF07635.6 EGC36240.1 - 2.5 8.4 5.1 2.1 8.7 0.6 2.5 2 1 1 3 3 3 0 Planctomycete cytochrome C HARP PF07443.8 EGC36240.1 - 4.1 6.8 7.9 4.2 6.8 0.4 3.3 2 1 1 3 3 3 0 HepA-related protein (HARP) TMCO5 PF14992.1 EGC36240.1 - 9 5.3 37.0 13 4.8 25.7 1.3 1 0 0 1 1 1 0 TMCO5 family FNIP PF05725.7 EGC36241.1 - 4.3e-58 193.0 64.2 2.1e-11 43.5 1.3 9.2 4 3 6 11 11 11 11 FNIP Repeat Inp1 PF12634.2 EGC36241.1 - 0.048 13.3 0.2 3.3 7.3 0.0 2.4 2 0 0 2 2 2 0 Inheritance of peroxisomes protein 1 YlqD PF11068.3 EGC36242.1 - 1.2 9.1 11.2 1.9 8.5 7.6 1.4 1 1 0 1 1 1 0 YlqD protein WD40 PF00400.27 EGC36245.1 - 8.6e-56 183.9 19.3 4.8e-08 32.5 0.0 9.0 8 0 0 8 8 8 8 WD domain, G-beta repeat DENN PF02141.16 EGC36245.1 - 5e-35 120.9 5.1 5e-35 120.9 3.6 2.5 2 2 0 2 2 2 1 DENN (AEX-3) domain uDENN PF03456.13 EGC36245.1 - 4.3e-14 52.2 0.0 1.6e-13 50.3 0.0 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGC36245.1 - 4.1e-08 33.1 0.2 1e-07 31.8 0.2 1.7 1 0 0 1 1 1 1 dDENN domain Cyclin_N PF00134.18 EGC36248.1 - 0.08 12.5 2.0 0.12 11.9 1.4 1.3 1 0 0 1 1 1 0 Cyclin, N-terminal domain RNA_pol_Rpc4 PF05132.9 EGC36248.1 - 0.1 12.5 3.8 0.16 11.9 2.7 1.2 1 0 0 1 1 1 0 RNA polymerase III RPC4 PRP1_N PF06424.7 EGC36248.1 - 0.24 11.6 7.7 0.35 11.1 5.4 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal RP-C_C PF11800.3 EGC36248.1 - 0.44 10.2 3.1 0.58 9.8 2.2 1.1 1 0 0 1 1 1 0 Replication protein C C-terminal region NTP_transferase PF00483.18 EGC36249.1 - 1.1e-46 159.2 0.0 1.4e-46 158.8 0.0 1.1 1 0 0 1 1 1 1 Nucleotidyl transferase Hexapep PF00132.19 EGC36249.1 - 2.7e-11 42.4 8.3 1.9e-07 30.2 0.4 4.5 2 1 1 4 4 4 3 Bacterial transferase hexapeptide (six repeats) NTP_transf_3 PF12804.2 EGC36249.1 - 9.6e-09 35.5 0.0 1.2e-08 35.2 0.0 1.2 1 0 0 1 1 1 1 MobA-like NTP transferase domain Hexapep_2 PF14602.1 EGC36249.1 - 0.0052 16.3 8.2 0.025 14.1 0.2 4.6 4 1 1 5 5 5 1 Hexapeptide repeat of succinyl-transferase GpcrRhopsn4 PF10192.4 EGC36250.1 - 8.5e-18 64.4 27.6 4.8e-17 61.9 9.7 2.7 1 1 1 2 2 2 2 Rhodopsin-like GPCR transmembrane domain DUF2391 PF09622.5 EGC36250.1 - 1.7 7.7 10.4 1.8 7.6 0.1 3.2 3 0 0 3 3 3 0 Putative integral membrane protein (DUF2391) DDE_3 PF13358.1 EGC36252.1 - 1.6e-10 40.9 0.1 1.7e-10 40.8 0.1 1.0 1 0 0 1 1 1 1 DDE superfamily endonuclease zf-RING_2 PF13639.1 EGC36253.1 - 4.6e-12 45.5 7.4 7.7e-12 44.8 5.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC36253.1 - 6.2e-09 35.3 5.6 9.6e-09 34.7 3.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC36253.1 - 7.7e-09 35.0 10.6 1.6e-08 34.0 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC36253.1 - 3.9e-07 29.6 8.8 7e-07 28.8 6.1 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC36253.1 - 4.8e-07 29.7 6.3 1.2e-06 28.4 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC36253.1 - 5.4e-07 29.5 9.9 8.9e-07 28.8 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC36253.1 - 0.00056 19.7 8.9 0.0014 18.4 5.8 2.0 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC36253.1 - 0.0015 18.2 2.0 0.01 15.5 1.3 2.6 1 1 1 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGC36253.1 - 0.0031 17.0 10.6 0.0058 16.1 7.4 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGC36253.1 - 0.0073 15.8 4.2 0.023 14.2 2.9 1.9 1 0 0 1 1 1 1 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC36253.1 - 0.014 15.2 2.1 0.028 14.2 1.5 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Antimicrobial19 PF08225.6 EGC36253.1 - 0.084 12.2 1.3 13 5.3 0.1 2.5 2 0 0 2 2 2 0 Pseudin antimicrobial peptide CAF-1_p150 PF11600.3 EGC36253.1 - 0.21 10.9 74.5 0.017 14.5 27.5 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal Methylase_S PF01420.14 EGC36254.1 - 0.079 12.9 2.7 0.079 12.9 1.9 1.0 1 0 0 1 1 1 0 Type I restriction modification DNA specificity domain ThiF PF00899.16 EGC36255.1 - 2.7e-10 40.1 0.0 7.8e-10 38.6 0.0 1.8 1 0 0 1 1 1 1 ThiF family Ctr PF04145.10 EGC36256.1 - 4.9e-19 68.8 19.3 1.4e-17 64.0 13.4 2.2 1 1 0 1 1 1 1 Ctr copper transporter family MFS_1 PF07690.11 EGC36256.1 - 0.00042 19.1 4.3 0.00054 18.7 3.0 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily MIF4G PF02854.14 EGC36256.1 - 0.017 14.5 2.1 0.023 14.1 1.4 1.1 1 0 0 1 1 1 0 MIF4G domain DUF4064 PF13273.1 EGC36256.1 - 0.21 11.6 7.1 2.5 8.2 0.1 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) DUF1049 PF06305.6 EGC36256.1 - 0.26 10.7 1.9 0.79 9.2 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) PTEN_C2 PF10409.4 EGC36257.1 - 6.7e-11 42.0 2.8 6.7e-11 42.0 1.9 2.6 3 1 0 3 3 3 1 C2 domain of PTEN tumour-suppressor protein DSPc PF00782.15 EGC36257.1 - 7.8e-08 31.9 0.0 7.8e-08 31.9 0.0 3.3 4 0 0 4 4 4 1 Dual specificity phosphatase, catalytic domain Y_phosphatase3 PF13350.1 EGC36257.1 - 0.00011 22.4 0.3 0.0064 16.7 0.0 2.8 2 0 0 2 2 2 1 Tyrosine phosphatase family CDKN3 PF05706.7 EGC36257.1 - 0.0036 16.7 0.0 0.0089 15.4 0.0 1.6 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) GCFC PF07842.7 EGC36258.1 - 3.8e-23 82.2 3.5 1e-22 80.7 1.5 2.5 1 1 0 1 1 1 1 GC-rich sequence DNA-binding factor-like protein RE_TdeIII PF09520.5 EGC36259.1 - 0.003 16.9 0.0 0.033 13.5 0.0 2.2 2 0 0 2 2 2 1 Type II restriction endonuclease, TdeIII DUF3294 PF07957.6 EGC36259.1 - 0.027 13.9 0.3 1.6 8.1 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3294) DUF2959 PF11172.3 EGC36259.1 - 0.056 13.1 4.0 0.42 10.3 0.2 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF2959) DUF3198 PF11433.3 EGC36259.1 - 0.077 12.8 0.6 0.92 9.4 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3198) Phage_connect_1 PF05135.8 EGC36259.1 - 0.099 12.8 1.2 0.46 10.6 0.2 2.2 2 1 0 2 2 2 0 Phage gp6-like head-tail connector protein ApoC-I PF04691.7 EGC36259.1 - 0.14 11.8 1.2 6.3 6.5 0.0 2.5 2 0 0 2 2 2 0 Apolipoprotein C-I (ApoC-1) CarbpepA_inh PF02977.10 EGC36260.1 - 0.097 12.2 1.7 0.15 11.6 1.2 1.4 1 0 0 1 1 1 0 Carboxypeptidase A inhibitor Tnp_zf-ribbon_2 PF13842.1 EGC36260.1 - 0.24 11.8 1.9 1.8 9.0 0.1 2.3 2 0 0 2 2 2 0 DDE_Tnp_1-like zinc-ribbon C1_2 PF03107.11 EGC36260.1 - 0.25 11.5 1.9 0.28 11.3 0.5 1.7 2 0 0 2 2 2 0 C1 domain NUDIX PF00293.23 EGC36264.1 - 3.7e-20 71.9 0.0 4.3e-20 71.7 0.0 1.0 1 0 0 1 1 1 1 NUDIX domain NUDIX_4 PF14815.1 EGC36264.1 - 9.8e-09 34.6 0.0 1.2e-08 34.3 0.0 1.1 1 0 0 1 1 1 1 NUDIX domain NUDIX_2 PF13869.1 EGC36264.1 - 0.0059 15.9 0.0 0.0083 15.4 0.0 1.3 1 0 0 1 1 1 1 Nucleotide hydrolase A_deaminase PF00962.17 EGC36265.1 - 3.1e-81 272.8 0.4 2e-70 237.3 0.0 2.2 2 0 0 2 2 2 2 Adenosine/AMP deaminase Glyco_transf_25 PF01755.12 EGC36266.1 - 0.00074 19.2 0.3 0.0011 18.6 0.2 1.5 1 0 0 1 1 1 1 Glycosyltransferase family 25 (LPS biosynthesis protein) DUF2117 PF09890.4 EGC36266.1 - 0.031 13.4 0.4 0.098 11.8 0.3 1.8 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2117) Rep_2 PF01719.12 EGC36266.1 - 0.053 13.0 4.5 0.076 12.5 3.1 1.3 1 0 0 1 1 1 0 Plasmid replication protein 5_nucleotid PF05761.9 EGC36267.1 - 9.7e-52 175.9 5.4 2.9e-51 174.3 3.8 1.7 1 1 0 1 1 1 1 5' nucleotidase family HAD_2 PF13419.1 EGC36267.1 - 2e-05 24.8 0.0 0.0037 17.5 0.0 2.8 3 0 0 3 3 3 2 Haloacid dehalogenase-like hydrolase DUF4615 PF15393.1 EGC36268.1 - 0.0082 16.3 0.9 0.0082 16.3 0.6 2.7 2 1 0 3 3 3 1 Domain of unknown function (DUF4615) Sigma_reg_N PF13800.1 EGC36268.1 - 0.067 13.2 0.2 0.067 13.2 0.1 2.2 2 0 0 2 2 2 0 Sigma factor regulator N-terminal FTO_CTD PF12934.2 EGC36268.1 - 0.11 12.1 6.2 4 6.9 1.5 2.4 2 0 0 2 2 2 0 FTO C-terminal domain CHASE3 PF05227.8 EGC36268.1 - 0.37 10.4 5.0 0.14 11.8 0.3 2.1 2 0 0 2 2 2 0 CHASE3 domain DUF3492 PF11997.3 EGC36268.1 - 6.6 6.1 6.9 2.6 7.5 2.5 1.7 1 1 0 2 2 2 0 Domain of unknown function (DUF3492) Ras PF00071.17 EGC36269.1 - 3.6e-48 163.0 0.4 4.5e-48 162.6 0.3 1.0 1 0 0 1 1 1 1 Ras family Arf PF00025.16 EGC36269.1 - 2.9e-19 68.9 0.3 3.6e-19 68.6 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC36269.1 - 3e-17 63.2 0.3 8.4e-17 61.7 0.1 1.7 2 0 0 2 2 2 1 Miro-like protein Gtr1_RagA PF04670.7 EGC36269.1 - 3.6e-09 36.1 0.3 4.3e-09 35.8 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC36269.1 - 4.5e-07 29.4 0.3 1.8e-05 24.2 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC36269.1 - 2.8e-05 24.0 0.0 4.2e-05 23.4 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC36269.1 - 0.0038 16.7 0.1 1.2 8.5 0.0 2.3 2 0 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC36269.1 - 0.012 14.8 0.0 0.013 14.6 0.0 1.2 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit AAA_22 PF13401.1 EGC36269.1 - 0.021 14.9 0.0 0.042 13.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_14 PF13173.1 EGC36269.1 - 0.028 14.3 0.1 0.075 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Cupin_4 PF08007.7 EGC36270.1 - 1.1e-64 218.7 0.0 1.5e-64 218.2 0.0 1.2 1 0 0 1 1 1 1 Cupin superfamily protein Cupin_8 PF13621.1 EGC36270.1 - 2.9e-10 40.0 0.7 1.9e-09 37.4 0.5 2.3 1 1 0 1 1 1 1 Cupin-like domain Cupin_2 PF07883.6 EGC36270.1 - 0.0034 16.8 0.0 0.035 13.5 0.0 2.4 2 0 0 2 2 2 1 Cupin domain Med21 PF11221.3 EGC36270.1 - 0.24 11.3 0.1 0.24 11.3 0.1 1.9 2 0 0 2 2 2 0 Subunit 21 of Mediator complex ATG11 PF10377.4 EGC36271.1 - 2 8.3 7.9 0.33 10.8 0.8 2.0 1 1 1 2 2 2 0 Autophagy-related protein 11 Neur_chan_memb PF02932.11 EGC36271.1 - 2.1 8.1 8.6 2.4 7.9 6.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med6 PF04934.9 EGC36271.1 - 4.6 6.7 6.0 6 6.4 4.2 1.4 1 1 0 1 1 1 0 MED6 mediator sub complex component AAA_23 PF13476.1 EGC36271.1 - 5.4 7.2 17.2 6 7.1 11.9 1.0 1 0 0 1 1 1 0 AAA domain FNIP PF05725.7 EGC36272.1 - 9.4e-80 262.3 36.6 1.3e-15 57.0 0.1 8.6 4 2 5 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 EGC36272.1 - 0.00097 19.0 14.5 0.15 12.0 0.1 6.2 4 2 4 8 8 8 4 Protein of unknown function (DUF1769) Bax1-I PF01027.15 EGC36273.1 - 5.5e-25 88.1 22.5 6.5e-25 87.9 15.6 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 DUF4271 PF14093.1 EGC36273.1 - 0.95 9.1 26.6 2 8.0 9.2 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4271) DUF308 PF03729.8 EGC36273.1 - 1 9.3 17.5 0.2 11.6 6.7 3.0 1 1 2 3 3 3 0 Short repeat of unknown function (DUF308) 7TMR-DISM_7TM PF07695.6 EGC36273.1 - 1.1 8.9 25.1 1.2 8.7 14.0 2.1 1 1 1 2 2 2 0 7TM diverse intracellular signalling Bax1-I PF01027.15 EGC36274.1 - 1.1e-14 54.5 33.1 1.4e-14 54.1 23.0 1.0 1 0 0 1 1 1 1 Inhibitor of apoptosis-promoting Bax1 Rsd_AlgQ PF04353.8 EGC36275.1 - 0.015 15.0 0.9 0.028 14.1 0.3 1.7 1 1 0 1 1 1 0 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ V-SNARE PF05008.10 EGC36275.1 - 0.044 13.9 5.4 0.083 13.0 2.5 2.4 1 1 0 1 1 1 0 Vesicle transport v-SNARE protein N-terminus SPT16 PF08644.6 EGC36275.1 - 0.099 12.4 5.1 0.14 11.9 3.3 1.4 1 1 0 1 1 1 0 FACT complex subunit (SPT16/CDC68) NVEALA PF14055.1 EGC36275.1 - 0.1 12.2 1.3 0.19 11.4 0.2 1.9 2 0 0 2 2 2 0 NVEALA protein YscO PF07321.7 EGC36275.1 - 0.15 11.8 4.3 0.28 10.9 3.0 1.4 1 1 0 1 1 1 0 Type III secretion protein YscO MSC PF09402.5 EGC36275.1 - 0.62 8.7 4.5 1.1 7.9 3.1 1.6 1 1 0 1 1 1 0 Man1-Src1p-C-terminal domain Syntaxin PF00804.20 EGC36275.1 - 4 7.6 9.8 9.7 6.4 5.3 2.3 2 1 0 2 2 2 0 Syntaxin Sgf11 PF08209.6 EGC36276.1 - 3e-09 36.0 0.6 5.3e-09 35.2 0.4 1.4 1 0 0 1 1 1 1 Sgf11 (transcriptional regulation protein) DUF1777 PF08648.7 EGC36276.1 - 5.6e-05 22.9 27.5 5.6e-05 22.9 19.0 10.6 4 1 3 7 7 7 3 Protein of unknown function (DUF1777) PRP38_assoc PF12871.2 EGC36276.1 - 0.0089 16.5 37.5 0.0089 16.5 26.0 11.9 4 2 4 8 8 8 1 Pre-mRNA-splicing factor 38-associated hydrophilic C-term PC_rep PF01851.17 EGC36277.1 - 7.9e-36 120.2 27.3 2.5e-06 27.4 0.1 9.5 9 0 0 9 9 9 7 Proteasome/cyclosome repeat HEAT_2 PF13646.1 EGC36277.1 - 4e-14 52.6 0.1 6.8e-10 39.0 0.0 3.2 1 1 2 3 3 3 3 HEAT repeats HEAT PF02985.17 EGC36277.1 - 1.1e-05 25.0 0.1 0.41 10.8 0.0 4.4 4 0 0 4 4 4 2 HEAT repeat HEAT_EZ PF13513.1 EGC36277.1 - 0.0026 18.1 0.1 10 6.7 0.0 3.7 4 0 0 4 4 4 2 HEAT-like repeat HEAT_PBS PF03130.11 EGC36277.1 - 0.024 15.0 1.9 4.4 8.0 0.0 4.1 4 0 0 4 4 4 0 PBS lyase HEAT-like repeat Btz PF09405.5 EGC36277.1 - 0.04 13.9 7.5 0.094 12.7 5.2 1.5 1 0 0 1 1 1 0 CASC3/Barentsz eIF4AIII binding PA26 PF04636.8 EGC36277.1 - 0.084 11.5 2.9 0.14 10.8 2.0 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) GAGA_bind PF06217.7 EGC36277.1 - 0.99 9.3 8.6 1.9 8.3 6.0 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family GOLD_2 PF13897.1 EGC36277.1 - 2.4 8.3 4.6 13 5.9 1.8 2.3 2 0 0 2 2 2 0 Golgi-dynamics membrane-trafficking DDHD PF02862.12 EGC36277.1 - 7.2 6.3 12.7 18 5.0 8.2 2.0 2 0 0 2 2 2 0 DDHD domain SnAC PF14619.1 EGC36278.1 - 0.085 13.0 0.2 0.085 13.0 0.1 2.4 2 0 0 2 2 2 0 Snf2-ATP coupling, chromatin remodelling complex EcsC PF12787.2 EGC36278.1 - 0.18 11.1 9.5 0.26 10.6 6.6 1.2 1 0 0 1 1 1 0 EcsC protein family Med15 PF09606.5 EGC36278.1 - 0.66 8.0 27.1 0.7 8.0 18.8 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ApbA_C PF08546.6 EGC36278.1 - 2.8 7.9 7.5 0.62 10.0 0.1 2.2 1 1 1 2 2 2 0 Ketopantoate reductase PanE/ApbA C terminal Endonuc_Holl PF10107.4 EGC36278.1 - 5.7 6.6 13.9 1.2 8.7 3.0 2.2 2 0 0 2 2 2 0 Endonuclease related to archaeal Holliday junction resolvase DUF1062 PF06353.7 EGC36279.1 - 0.0017 18.5 1.6 0.17 12.1 0.2 2.7 2 0 0 2 2 2 2 Protein of unknown function (DUF1062) DUF1479 PF07350.7 EGC36280.1 - 1.3e-07 30.5 0.4 0.0019 16.7 0.0 3.0 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EGC36280.1 - 8.4e-05 22.6 0.0 0.0042 17.1 0.0 2.3 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) GST_C PF00043.20 EGC36282.1 - 2.5e-12 46.6 0.0 5.4e-12 45.5 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC36282.1 - 9.4e-11 41.7 0.0 1.8e-10 40.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC36282.1 - 3.2e-10 39.8 0.0 7.3e-10 38.7 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC36282.1 - 3.8e-10 39.5 0.0 7.5e-10 38.5 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N PF02798.15 EGC36282.1 - 2.7e-09 37.0 0.1 7.7e-09 35.6 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC36282.1 - 2.3e-06 27.9 0.1 5.2e-06 26.8 0.0 1.7 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain Aminotran_1_2 PF00155.16 EGC36283.1 - 2.8e-65 220.6 0.0 3.2e-65 220.4 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGC36283.1 - 4.1e-08 32.3 0.0 7.4e-08 31.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGC36283.1 - 5.1e-08 31.5 0.0 1.8e-07 29.8 0.0 1.7 2 0 0 2 2 2 1 Cys/Met metabolism PLP-dependent enzyme Beta_elim_lyase PF01212.16 EGC36283.1 - 7.9e-08 31.7 0.0 1.2e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGC36283.1 - 0.001 18.1 0.0 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Met_gamma_lyase PF06838.6 EGC36283.1 - 0.033 12.4 0.0 0.062 11.5 0.0 1.4 1 1 0 1 1 1 0 Methionine gamma-lyase UPF0253 PF06786.7 EGC36283.1 - 0.13 12.3 0.7 60 3.8 0.0 3.9 4 0 0 4 4 4 0 Uncharacterised protein family (UPF0253) Homeobox PF00046.24 EGC36284.1 - 4.3e-14 51.8 9.7 3.7e-08 32.8 1.8 2.9 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 EGC36284.1 - 3e-06 26.8 0.5 0.049 13.3 0.0 3.0 2 0 0 2 2 2 2 Homeobox KN domain DUF2778 PF10908.3 EGC36285.1 - 3.3e-07 30.5 0.4 7.3e-06 26.1 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF2778) YkuD PF03734.9 EGC36285.1 - 0.00028 21.1 0.5 0.00038 20.7 0.3 1.2 1 0 0 1 1 1 1 L,D-transpeptidase catalytic domain Nucleoporin_FG PF13634.1 EGC36286.1 - 1.9e-12 47.3 208.3 2.8e-06 27.5 29.9 7.8 4 1 3 7 7 7 6 Nucleoporin FG repeat region NAD_binding_6 PF08030.7 EGC36287.1 - 9.8e-30 103.5 0.0 1.5e-29 102.8 0.0 1.3 1 0 0 1 1 1 1 Ferric reductase NAD binding domain FAD_binding_8 PF08022.7 EGC36287.1 - 4.1e-21 74.8 0.0 7.5e-21 73.9 0.0 1.4 1 0 0 1 1 1 1 FAD-binding domain Ferric_reduct PF01794.14 EGC36287.1 - 2e-17 63.4 7.0 3.9e-17 62.5 4.8 1.5 1 0 0 1 1 1 1 Ferric reductase like transmembrane component FAD_binding_6 PF00970.19 EGC36287.1 - 4.1e-06 26.8 0.0 1e-05 25.5 0.0 1.6 1 1 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGC36287.1 - 0.0069 16.9 0.0 0.077 13.5 0.0 2.3 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain MFS_1 PF07690.11 EGC36288.1 - 3.1e-27 95.2 23.3 2.5e-24 85.6 3.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_3 PF05977.8 EGC36288.1 - 1.2e-23 83.0 9.8 4.8e-20 71.1 2.7 2.2 2 0 0 2 2 2 2 Transmembrane secretion effector Macoilin PF09726.4 EGC36288.1 - 0.00031 19.2 8.5 0.00031 19.2 5.9 2.3 1 1 0 2 2 2 1 Transmembrane protein MFS_2 PF13347.1 EGC36288.1 - 0.002 16.5 7.2 0.002 16.5 5.0 2.8 2 1 1 3 3 3 2 MFS/sugar transport protein DUF853 PF05872.7 EGC36288.1 - 0.057 11.7 3.3 0.13 10.6 2.3 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Vmethyltransf_C PF08456.5 EGC36288.1 - 0.34 10.2 6.2 0.072 12.4 1.5 1.9 2 0 0 2 2 2 0 Viral methyltransferase C-terminal Peptidase_C48 PF02902.14 EGC36291.1 - 2.5e-31 108.9 4.3 2.5e-31 108.9 3.0 2.7 2 1 0 3 3 3 1 Ulp1 protease family, C-terminal catalytic domain tRNA_anti-codon PF01336.20 EGC36292.1 - 6.1e-15 54.8 0.0 4.8e-06 26.3 0.1 3.2 3 0 0 3 3 3 2 OB-fold nucleic acid binding domain Rep_fac-A_C PF08646.5 EGC36292.1 - 4.3e-07 29.7 13.1 1.2e-06 28.3 2.3 3.9 4 0 0 4 4 4 2 Replication factor-A C terminal domain RP-C_C PF11800.3 EGC36292.1 - 0.79 9.3 3.6 1.7 8.2 2.5 1.6 1 0 0 1 1 1 0 Replication protein C C-terminal region COG5 PF10392.4 EGC36293.1 - 3.5e-23 82.0 3.4 3.5e-23 82.0 2.4 4.5 3 1 1 4 4 4 1 Golgi transport complex subunit 5 COG2 PF06148.6 EGC36293.1 - 1.4e-11 44.3 4.0 1.4e-11 44.3 2.8 3.0 3 0 0 3 3 3 1 COG (conserved oligomeric Golgi) complex component, COG2 Vps51 PF08700.6 EGC36293.1 - 0.022 14.5 0.9 0.022 14.5 0.6 3.7 3 0 0 3 3 3 0 Vps51/Vps67 DUF2419 PF10343.4 EGC36294.1 - 4.2e-92 308.4 0.0 6.7e-92 307.7 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2419) DUF1688 PF07958.6 EGC36294.1 - 0.028 12.9 0.0 0.76 8.2 0.0 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1688) FNIP PF05725.7 EGC36295.1 - 3e-21 75.1 29.9 3.1e-05 23.8 1.0 4.7 1 1 4 6 6 6 6 FNIP Repeat Thaumatin PF00314.12 EGC36295.1 - 0.061 12.7 0.0 20 4.5 0.0 3.5 1 1 2 4 4 4 0 Thaumatin family EAF PF09816.4 EGC36295.1 - 0.13 12.2 0.1 12 5.8 0.0 2.9 3 0 0 3 3 3 0 RNA polymerase II transcription elongation factor DUF1765 PF08578.5 EGC36296.1 - 1.9 8.5 6.5 0.25 11.4 1.5 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1765) HEAT_2 PF13646.1 EGC36298.1 - 5.5e-07 29.7 0.1 0.0097 16.1 0.0 3.8 2 2 1 3 3 3 2 HEAT repeats LisH PF08513.6 EGC36298.1 - 0.003 17.2 3.3 0.036 13.8 0.1 2.8 2 0 0 2 2 2 1 LisH HEAT PF02985.17 EGC36298.1 - 0.012 15.6 12.8 1 9.6 0.0 6.6 7 0 0 7 7 7 0 HEAT repeat DUF4398 PF14346.1 EGC36299.1 - 0.0047 16.9 1.0 0.0079 16.2 0.7 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4398) Tape_meas_lam_C PF09718.5 EGC36299.1 - 0.0075 16.1 2.5 0.024 14.5 0.5 2.2 1 1 1 2 2 2 1 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF883 PF05957.8 EGC36299.1 - 0.008 16.5 0.2 0.44 10.9 0.0 2.2 1 1 1 2 2 2 1 Bacterial protein of unknown function (DUF883) Baculo_PEP_C PF04513.7 EGC36299.1 - 0.033 14.0 3.3 0.044 13.5 2.3 1.1 1 0 0 1 1 1 0 Baculovirus polyhedron envelope protein, PEP, C terminus DUF1664 PF07889.7 EGC36299.1 - 0.042 13.6 2.8 0.087 12.6 0.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) THOC7 PF05615.8 EGC36299.1 - 0.045 14.0 6.1 0.95 9.7 0.4 2.2 1 1 1 2 2 2 0 Tho complex subunit 7 COG2 PF06148.6 EGC36299.1 - 0.13 12.1 1.2 0.69 9.7 0.4 1.9 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF533 PF04391.7 EGC36299.1 - 0.15 11.3 1.3 0.16 11.2 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF533) DUF2648 PF10855.3 EGC36299.1 - 0.16 11.4 0.2 0.16 11.4 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2648) DUF677 PF05055.7 EGC36299.1 - 0.16 10.6 2.7 0.19 10.3 1.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF677) CoatB PF10389.4 EGC36299.1 - 0.17 11.8 0.4 6.4 6.7 0.1 2.6 2 1 1 3 3 3 0 Bacteriophage coat protein B YtxH PF12732.2 EGC36299.1 - 1.6 9.1 8.1 68 3.9 5.6 2.4 1 1 0 1 1 1 0 YtxH-like protein FAD_binding_4 PF01565.18 EGC36301.1 - 7.3e-27 93.5 0.3 1.1e-26 92.9 0.2 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC36301.1 - 1.3e-06 28.2 0.3 2.6e-06 27.2 0.2 1.6 1 0 0 1 1 1 1 Berberine and berberine like Metallophos_3 PF14582.1 EGC36301.1 - 0.14 11.3 0.0 0.2 10.7 0.0 1.2 1 0 0 1 1 1 0 Metallophosphoesterase, calcineurin superfamily SHNi-TPR PF10516.4 EGC36301.1 - 0.73 9.1 3.5 6.1 6.1 0.0 3.1 3 0 0 3 3 3 0 SHNi-TPR FAD_binding_4 PF01565.18 EGC36302.1 - 1.1e-25 89.7 0.0 2e-25 88.8 0.0 1.5 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC36302.1 - 3.6e-09 36.3 0.4 6.7e-09 35.5 0.3 1.5 1 0 0 1 1 1 1 Berberine and berberine like BAP PF06639.6 EGC36303.1 - 0.66 9.7 3.4 3.9 7.2 0.0 2.2 2 0 0 2 2 2 0 Basal layer antifungal peptide (BAP) DUF613 PF04764.7 EGC36303.1 - 3.5 7.5 11.0 0.89 9.4 5.5 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF613) L_protein_N PF15518.1 EGC36304.1 - 0.0085 15.4 2.4 0.014 14.7 1.7 1.3 1 0 0 1 1 1 1 L protein N-terminus Ribosomal_L7Ae PF01248.21 EGC36306.1 - 1.2e-19 69.6 1.4 1.9e-19 68.9 0.9 1.3 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family HR1 PF02185.11 EGC36306.1 - 0.048 13.4 2.1 0.069 12.8 0.2 2.0 2 0 0 2 2 2 0 Hr1 repeat LRR_4 PF12799.2 EGC36307.1 - 0.00061 19.3 65.5 0.28 10.8 1.0 10.4 5 3 5 10 10 10 7 Leucine Rich repeats (2 copies) F-box-like PF12937.2 EGC36307.1 - 0.0022 17.6 0.0 0.0048 16.5 0.0 1.5 1 0 0 1 1 1 1 F-box-like LRR_6 PF13516.1 EGC36307.1 - 0.048 13.7 58.0 2.3 8.5 0.4 12.7 13 1 1 14 14 14 0 Leucine Rich repeat DUF4368 PF14287.1 EGC36307.1 - 0.065 13.0 0.2 0.19 11.5 0.2 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4368) GSIII_N PF12437.3 EGC36307.1 - 0.18 11.1 1.4 16 4.8 0.0 2.5 2 0 0 2 2 2 0 Glutamine synthetase type III N terminal LRR_7 PF13504.1 EGC36307.1 - 7.5 7.2 37.5 8.7 7.0 1.3 11.0 12 0 0 12 12 12 0 Leucine rich repeat Pkinase PF00069.20 EGC36308.1 - 7.4e-41 140.0 0.0 9.7e-41 139.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36308.1 - 3.6e-35 121.3 0.1 4.4e-35 121.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase PIP49_C PF12260.3 EGC36308.1 - 0.0006 19.2 0.6 0.002 17.6 0.0 2.0 2 0 0 2 2 2 1 Protein-kinase domain of FAM69 Asp PF00026.18 EGC36308.1 - 0.05 12.8 0.1 0.069 12.3 0.0 1.2 1 0 0 1 1 1 0 Eukaryotic aspartyl protease APH PF01636.18 EGC36308.1 - 0.13 11.9 0.0 0.36 10.5 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family WH1 PF00568.18 EGC36309.1 - 2.6e-18 65.7 0.1 3.5e-18 65.3 0.0 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EGC36309.1 - 8.7e-09 34.7 0.2 8.7e-09 34.7 0.1 2.3 3 0 0 3 3 3 1 WH2 motif VASP_tetra PF08776.6 EGC36309.1 - 1e-07 31.1 2.6 1.5e-07 30.6 1.8 1.2 1 0 0 1 1 1 1 VASP tetramerisation domain PIG-S PF10510.4 EGC36310.1 - 6e-118 394.7 13.1 1.5e-111 373.6 5.8 2.0 1 1 1 2 2 2 2 Phosphatidylinositol-glycan biosynthesis class S protein Rft-1 PF04506.8 EGC36313.1 - 3.2e-57 194.1 24.9 4.8e-57 193.5 17.2 1.2 1 0 0 1 1 1 1 Rft protein TMEM223 PF14640.1 EGC36313.1 - 0.0057 16.6 1.4 12 5.8 0.0 3.5 3 0 0 3 3 3 1 Transmembrane protein 223 DUF912 PF06024.7 EGC36313.1 - 0.029 14.4 1.4 0.029 14.4 1.0 3.6 2 1 3 5 5 5 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Gemini_mov PF01708.11 EGC36313.1 - 0.046 13.2 2.6 0.58 9.7 0.4 3.0 3 0 0 3 3 3 0 Geminivirus putative movement protein DUF2101 PF09874.4 EGC36313.1 - 1.7 8.1 20.0 0.049 13.1 9.4 1.7 2 0 0 2 2 2 0 Predicted membrane protein (DUF2101) Arf PF00025.16 EGC36315.1 - 6.6e-66 220.8 0.2 7.8e-66 220.6 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC36315.1 - 1.7e-13 50.2 0.0 1.9e-13 50.1 0.0 1.1 1 0 0 1 1 1 1 Ras family SRPRB PF09439.5 EGC36315.1 - 1.3e-12 47.2 0.0 1.6e-12 47.0 0.0 1.0 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC36315.1 - 2.6e-10 40.8 0.0 3.6e-10 40.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Gtr1_RagA PF04670.7 EGC36315.1 - 1.2e-09 37.7 0.0 1.4e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGC36315.1 - 5.3e-09 35.2 2.7 9e-07 27.9 0.2 2.3 1 1 1 2 2 2 2 G-protein alpha subunit MMR_HSR1 PF01926.18 EGC36315.1 - 3.7e-06 26.8 0.0 4.9e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase ABC_tran PF00005.22 EGC36315.1 - 0.009 16.3 0.0 0.013 15.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter KAP_NTPase PF07693.9 EGC36315.1 - 0.045 12.7 0.1 0.17 10.8 0.0 1.8 2 0 0 2 2 2 0 KAP family P-loop domain Ectoine_synth PF06339.7 EGC36315.1 - 0.066 13.1 0.0 0.094 12.6 0.0 1.4 1 0 0 1 1 1 0 Ectoine synthase NACHT PF05729.7 EGC36315.1 - 0.11 12.1 0.2 3.4 7.3 0.1 2.2 2 0 0 2 2 2 0 NACHT domain CENP-M PF11111.3 EGC36315.1 - 0.12 11.6 0.0 0.17 11.0 0.0 1.2 1 0 0 1 1 1 0 Centromere protein M (CENP-M) ECH_C PF13766.1 EGC36316.1 - 4.5e-34 117.1 0.0 8.5e-34 116.2 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region ECH PF00378.15 EGC36316.1 - 7.2e-31 107.1 0.0 1.1e-30 106.6 0.0 1.3 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family zf-UBR PF02207.15 EGC36317.1 - 9.8e-19 66.8 10.9 9.8e-19 66.8 7.6 2.8 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EGC36317.1 - 0.0015 18.3 2.1 0.0015 18.3 1.4 3.9 4 0 0 4 4 4 1 Ring finger domain SET PF00856.23 EGC36318.1 - 4.4e-09 36.8 2.7 1.8e-07 31.6 1.9 2.3 1 1 0 1 1 1 1 SET domain zf-MYND PF01753.13 EGC36318.1 - 0.0015 18.3 5.3 0.0015 18.3 3.7 2.3 2 0 0 2 2 2 1 MYND finger LigB PF02900.13 EGC36319.1 - 5.6e-54 182.9 0.0 6.4e-54 182.7 0.0 1.0 1 0 0 1 1 1 1 Catalytic LigB subunit of aromatic ring-opening dioxygenase FKBP_C PF00254.23 EGC36320.1 - 2.7e-33 113.8 0.0 3.4e-33 113.5 0.0 1.1 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase Chordopox_G3 PF06129.7 EGC36320.1 - 0.014 15.5 0.0 0.02 15.0 0.0 1.1 1 0 0 1 1 1 0 Chordopoxvirus G3 protein Mito_carr PF00153.22 EGC36321.1 - 8.5e-74 243.3 1.3 6.2e-26 89.9 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein DREV PF05219.7 EGC36324.1 - 7e-56 189.0 1.4 9.4e-56 188.5 1.0 1.1 1 0 0 1 1 1 1 DREV methyltransferase Methyltransf_11 PF08241.7 EGC36324.1 - 1.5e-09 38.2 0.0 4.1e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36324.1 - 5e-09 36.5 1.0 1.2e-08 35.2 0.0 2.2 4 0 0 4 4 4 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36324.1 - 7.2e-08 32.3 0.0 1.3e-07 31.5 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC36324.1 - 7.8e-07 28.8 0.1 1.5e-06 27.8 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36324.1 - 0.015 15.8 0.0 0.046 14.3 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_9 PF08003.6 EGC36324.1 - 0.017 13.8 0.0 0.025 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) GAGA_bind PF06217.7 EGC36325.1 - 0.34 10.8 11.5 0.36 10.7 8.0 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family POX PF07526.6 EGC36325.1 - 0.41 10.8 5.0 0.49 10.6 3.5 1.3 1 0 0 1 1 1 0 Associated with HOX Bap31 PF05529.7 EGC36325.1 - 1.7 8.0 8.4 2.3 7.6 5.8 1.2 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Band_3_cyto PF07565.8 EGC36325.1 - 2.6 7.4 5.9 3.1 7.2 4.1 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gon7 PF08738.5 EGC36325.1 - 5.3 7.0 10.5 33 4.5 7.3 2.0 1 1 0 1 1 1 0 Gon7 family PyrI PF01948.13 EGC36326.1 - 0.49 10.4 4.4 0.1 12.6 0.8 1.5 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, allosteric domain Mito_carr PF00153.22 EGC36327.1 - 0.11 12.1 0.0 0.48 10.1 0.0 2.1 2 0 0 2 2 2 0 Mitochondrial carrier protein NPCC PF08058.6 EGC36327.1 - 2.5 7.9 7.6 0.73 9.6 1.0 2.7 2 1 1 3 3 3 0 Nuclear pore complex component WD40 PF00400.27 EGC36328.1 - 0.00088 19.0 0.1 0.036 13.9 0.0 2.7 2 0 0 2 2 2 1 WD domain, G-beta repeat BBS1 PF14779.1 EGC36328.1 - 0.02 13.8 0.0 0.039 12.9 0.0 1.4 1 0 0 1 1 1 0 Ciliary BBSome complex subunit 1 Med12 PF09497.5 EGC36329.1 - 1.5e-18 66.5 0.1 3.9e-18 65.1 0.1 1.8 1 0 0 1 1 1 1 Transcription mediator complex subunit Med12 Med12-LCEWAV PF12145.3 EGC36329.1 - 3.8e-06 25.6 0.1 3.8e-06 25.6 0.1 4.9 2 2 2 4 4 4 2 Eukaryotic Mediator 12 subunit domain DUF2457 PF10446.4 EGC36329.1 - 1.6 7.3 23.3 4.5 5.8 16.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) EF-hand_1 PF00036.27 EGC36330.1 - 1.9e-08 32.9 0.4 6.2e-06 25.1 0.1 2.2 2 0 0 2 2 2 2 EF hand EF-hand_7 PF13499.1 EGC36330.1 - 5.2e-08 32.9 0.0 6.7e-05 22.9 0.0 2.1 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC36330.1 - 1e-07 31.2 0.1 9.6e-05 21.9 0.0 2.2 2 0 0 2 2 2 2 EF-hand domain EF-hand_5 PF13202.1 EGC36330.1 - 7.5e-06 25.0 0.0 9.6e-05 21.5 0.0 2.1 2 0 0 2 2 2 1 EF hand Tannase PF07519.6 EGC36330.1 - 0.0011 17.7 0.0 0.0012 17.6 0.0 1.0 1 0 0 1 1 1 1 Tannase and feruloyl esterase EF-hand_8 PF13833.1 EGC36330.1 - 0.0052 16.3 0.3 0.13 11.8 0.1 2.2 2 0 0 2 2 2 1 EF-hand domain pair Chromo PF00385.19 EGC36332.1 - 1.9e-07 30.6 0.1 2.5e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC36332.1 - 0.088 12.5 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Coiled PF05710.7 EGC36334.1 - 9.3e-07 29.2 6.6 1.1e-06 29.0 4.6 1.1 1 0 0 1 1 1 1 Coiled coil Mito_fiss_reg PF05308.6 EGC36334.1 - 0.53 9.6 6.4 0.65 9.3 4.5 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Coiled PF05710.7 EGC36335.1 - 1.1e-06 28.9 6.4 1.3e-06 28.7 4.5 1.1 1 0 0 1 1 1 1 Coiled coil Mito_fiss_reg PF05308.6 EGC36335.1 - 0.47 9.7 6.2 0.58 9.4 4.3 1.2 1 0 0 1 1 1 0 Mitochondrial fission regulator Phage_lysis PF03245.8 EGC36336.1 - 0.0048 16.8 0.9 0.0073 16.2 0.6 1.3 1 0 0 1 1 1 1 Bacteriophage Rz lysis protein CPDase PF07823.6 EGC36336.1 - 0.04 13.4 0.1 0.071 12.5 0.1 1.4 1 1 0 1 1 1 0 Cyclic phosphodiesterase-like protein CTC1 PF15489.1 EGC36337.1 - 0.051 10.9 0.0 0.071 10.4 0.0 1.1 1 0 0 1 1 1 0 CST, telomere maintenance, complex subunit CTC1 Carb_kinase PF01256.12 EGC36338.1 - 6e-52 176.3 0.0 7.7e-52 175.9 0.0 1.1 1 0 0 1 1 1 1 Carbohydrate kinase HK PF02110.10 EGC36338.1 - 9.1e-06 25.0 0.0 1.6e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Hydroxyethylthiazole kinase family Phos_pyr_kin PF08543.7 EGC36338.1 - 0.035 13.2 0.0 0.053 12.7 0.0 1.2 1 0 0 1 1 1 0 Phosphomethylpyrimidine kinase TPR_12 PF13424.1 EGC36340.1 - 0.034 14.0 0.0 0.1 12.5 0.0 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat DUF1604 PF07713.8 EGC36342.1 - 3.5e-35 119.6 1.4 3.5e-35 119.6 0.9 4.0 4 0 0 4 4 4 1 Protein of unknown function (DUF1604) DUF3357 PF11837.3 EGC36343.1 - 0.0034 17.1 5.4 2 8.3 0.1 3.7 1 1 3 4 4 4 3 Domain of unknown function (DUF3357) EphA2_TM PF14575.1 EGC36343.1 - 0.032 14.6 3.2 10 6.5 0.1 3.6 2 1 2 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF1275 PF06912.6 EGC36343.1 - 0.034 13.3 5.7 0.072 12.2 1.5 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF1275) DUF1345 PF07077.6 EGC36343.1 - 0.039 13.4 1.5 0.2 11.1 0.2 2.0 1 1 0 2 2 2 0 Protein of unknown function (DUF1345) Iron_permease PF04120.7 EGC36343.1 - 0.21 11.1 1.0 2.1 7.9 0.0 2.9 4 0 0 4 4 4 0 Low affinity iron permease Cyto_ox_2 PF02322.10 EGC36343.1 - 0.28 10.3 6.6 0.25 10.4 2.5 1.9 1 1 1 2 2 2 0 Cytochrome oxidase subunit II DUF4401 PF14351.1 EGC36343.1 - 0.58 9.1 7.0 0.36 9.7 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF4149 PF13664.1 EGC36343.1 - 0.64 10.1 3.8 0.81 9.7 0.7 2.2 1 1 0 2 2 2 0 Domain of unknown function (DUF4149) Plant_vir_prot PF01307.12 EGC36343.1 - 1.4 8.6 16.4 1.5 8.6 1.1 4.6 1 1 4 5 5 5 0 Plant viral movement protein MARVEL PF01284.18 EGC36343.1 - 2.8 7.7 9.0 70 3.2 6.0 2.9 1 1 0 1 1 1 0 Membrane-associating domain DUF805 PF05656.9 EGC36343.1 - 8.7 6.1 7.3 56 3.5 3.3 2.6 1 1 1 2 2 2 0 Protein of unknown function (DUF805) PH PF00169.24 EGC36344.1 - 3.4e-14 52.8 0.6 3.4e-14 52.8 0.4 2.0 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC36344.1 - 2.1e-05 24.7 9.5 8.7e-05 22.7 1.4 4.2 3 1 0 3 3 3 1 Pleckstrin homology domain TPR_12 PF13424.1 EGC36344.1 - 3.7e-05 23.5 0.1 0.0023 17.8 0.0 2.9 3 0 0 3 3 3 1 Tetratricopeptide repeat RUN PF02759.14 EGC36344.1 - 0.065 12.9 4.4 0.64 9.7 0.0 3.1 3 0 0 3 3 3 0 RUN domain CK2S PF15011.1 EGC36345.1 - 0.01 15.6 0.1 0.074 12.8 0.0 2.2 2 1 0 2 2 2 0 Casein Kinase 2 substrate Fib_alpha PF08702.5 EGC36345.1 - 0.1 12.6 10.5 0.26 11.4 2.5 2.8 1 1 2 3 3 3 0 Fibrinogen alpha/beta chain family DUF948 PF06103.6 EGC36345.1 - 0.35 10.7 5.5 0.43 10.4 0.6 2.8 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) Med28 PF11594.3 EGC36345.1 - 0.36 11.0 5.1 0.68 10.2 1.0 2.6 1 1 0 2 2 2 0 Mediator complex subunit 28 V-SNARE_C PF12352.3 EGC36345.1 - 0.56 10.3 4.5 1.1 9.4 0.5 2.9 3 0 0 3 3 3 0 Snare region anchored in the vesicle membrane C-terminus WXG100 PF06013.7 EGC36345.1 - 0.8 9.7 3.1 16 5.5 0.1 2.9 3 0 0 3 3 3 0 Proteins of 100 residues with WXG DUF4298 PF14131.1 EGC36345.1 - 3.8 7.4 7.9 7.1 6.5 0.3 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF4298) Rho_Binding PF08912.6 EGC36345.1 - 4.3 7.7 7.5 0.38 11.0 0.5 2.5 3 0 0 3 3 3 0 Rho Binding Med2 PF11214.3 EGC36345.1 - 9.9 6.2 14.0 8.7 6.4 0.1 3.4 1 1 3 4 4 4 0 Mediator complex subunit 2 RabGAP-TBC PF00566.13 EGC36346.1 - 3.7e-51 173.6 0.1 3.7e-51 173.6 0.1 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain F-box-like PF12937.2 EGC36346.1 - 9.1e-09 34.9 0.9 2.1e-07 30.5 0.4 2.9 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC36346.1 - 7.4e-05 22.3 1.3 0.00022 20.7 0.9 1.8 1 0 0 1 1 1 1 F-box domain Mucin PF01456.12 EGC36346.1 - 2.2 8.0 26.7 4.6 7.0 18.5 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein MTS PF05175.9 EGC36347.1 - 1.9e-05 24.0 0.0 3.3e-05 23.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGC36347.1 - 0.09 13.2 0.0 0.27 11.7 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36347.1 - 0.09 13.3 0.0 0.35 11.4 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain OPT PF03169.10 EGC36348.1 - 5.1e-146 487.6 18.3 5.8e-146 487.4 12.7 1.0 1 0 0 1 1 1 1 OPT oligopeptide transporter protein RseC_MucC PF04246.7 EGC36348.1 - 0.17 11.4 1.2 0.74 9.3 0.0 2.8 2 0 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC QCR10 PF09796.4 EGC36348.1 - 1.9 8.1 7.1 9.6 5.9 0.9 3.1 3 0 0 3 3 3 0 Ubiquinol-cytochrome-c reductase complex subunit (QCR10) DUF3093 PF11292.3 EGC36348.1 - 9.3 6.0 6.8 0.66 9.7 0.2 2.3 3 0 0 3 3 3 0 Protein of unknown function (DUF3093) tRNA-synt_1 PF00133.17 EGC36349.1 - 1.6e-61 208.1 5.9 8.4e-37 126.4 3.0 6.1 2 1 1 3 3 3 3 tRNA synthetases class I (I, L, M and V) tRNA-synt_1_2 PF13603.1 EGC36349.1 - 2.5e-41 141.0 0.4 1.5e-40 138.4 0.0 2.1 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 tRNA-synt_1g PF09334.6 EGC36349.1 - 2.9e-31 108.5 0.1 3.3e-21 75.4 0.0 4.3 3 1 0 3 3 3 3 tRNA synthetases class I (M) Anticodon_1 PF08264.8 EGC36349.1 - 1.1e-09 38.2 0.0 2.9e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1e PF01406.14 EGC36349.1 - 1.5e-05 24.2 0.1 0.1 11.7 0.1 2.6 2 0 0 2 2 2 2 tRNA synthetases class I (C) catalytic domain tRNA-synt_1d PF00750.14 EGC36349.1 - 0.00033 19.5 0.0 0.0016 17.3 0.0 2.0 2 0 0 2 2 2 1 tRNA synthetases class I (R) tRNA-synt_1f PF01921.13 EGC36349.1 - 0.0043 15.7 0.2 0.2 10.2 0.0 3.0 2 1 1 3 3 3 1 tRNA synthetases class I (K) tRNA-synt_1c PF00749.16 EGC36349.1 - 0.015 14.0 0.2 1.1 7.8 0.1 2.4 2 0 0 2 2 2 0 tRNA synthetases class I (E and Q), catalytic domain Ogr_Delta PF04606.7 EGC36349.1 - 0.26 10.9 2.3 1.3 8.7 0.2 2.5 2 0 0 2 2 2 0 Ogr/Delta-like zinc finger ABC2_membrane_3 PF12698.2 EGC36350.1 - 3.7e-35 121.5 37.1 5.3e-35 121.0 25.7 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein ABC_tran PF00005.22 EGC36350.1 - 4.3e-28 98.3 0.0 7.1e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC36350.1 - 3.7e-10 40.2 7.9 3.9e-09 36.8 0.1 4.0 2 2 0 2 2 2 1 AAA domain ABC2_membrane_2 PF12679.2 EGC36350.1 - 0.00043 19.2 20.7 0.00043 19.2 14.3 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_16 PF13191.1 EGC36350.1 - 0.024 14.6 0.0 0.041 13.8 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Miro PF08477.8 EGC36350.1 - 0.099 13.1 0.0 0.22 11.9 0.0 1.6 1 0 0 1 1 1 0 Miro-like protein SRP54 PF00448.17 EGC36350.1 - 0.13 11.6 0.2 0.24 10.8 0.1 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain 2OG-FeII_Oxy_3 PF13640.1 EGC36351.1 - 3.3e-06 27.5 0.3 1.1e-05 25.8 0.0 2.0 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGC36351.1 - 0.0075 16.5 0.4 0.032 14.5 0.1 2.3 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily Peptidase_S31 PF05578.7 EGC36351.1 - 0.16 11.1 0.0 0.47 9.6 0.0 1.7 2 0 0 2 2 2 0 Pestivirus NS3 polyprotein peptidase S31 2OG-FeII_Oxy_3 PF13640.1 EGC36352.1 - 1.7e-06 28.4 0.6 4.2e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily 2OG-FeII_Oxy PF03171.15 EGC36352.1 - 0.0083 16.3 0.7 0.028 14.7 0.1 2.1 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily DUF2414 PF10309.4 EGC36352.1 - 0.041 13.5 0.9 0.73 9.5 0.0 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF2414) Kelch_3 PF13415.1 EGC36354.1 - 8.1e-43 143.6 7.6 3e-12 46.3 0.0 7.5 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC36354.1 - 5.8e-41 138.0 10.5 2.5e-12 46.3 0.0 6.6 6 0 0 6 6 6 5 Galactose oxidase, central domain RhoGAP PF00620.22 EGC36354.1 - 9.6e-33 112.9 0.1 9.6e-33 112.9 0.0 2.9 3 0 0 3 3 3 1 RhoGAP domain Kelch_5 PF13854.1 EGC36354.1 - 1.2e-31 108.1 10.8 1.8e-07 30.9 0.3 6.8 6 0 0 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC36354.1 - 1.8e-25 87.6 8.9 3.2e-06 26.6 0.0 7.5 7 0 0 7 7 7 4 Kelch motif Kelch_6 PF13964.1 EGC36354.1 - 5.2e-25 86.5 17.2 2.8e-08 33.5 0.1 6.9 3 2 3 6 6 6 5 Kelch motif Kelch_1 PF01344.20 EGC36354.1 - 2e-20 72.0 12.1 4.6e-07 29.2 0.0 6.8 6 1 0 6 6 6 5 Kelch motif CAF-1_p150 PF11600.3 EGC36354.1 - 0.0011 18.3 61.5 0.0011 18.3 42.6 5.4 5 1 1 6 6 6 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal IPPT PF01715.12 EGC36355.1 - 2.5e-46 157.7 5.5 7.2e-43 146.4 0.7 2.2 2 0 0 2 2 2 2 IPP transferase AAA_17 PF13207.1 EGC36355.1 - 9.7e-07 29.6 0.9 4.5e-06 27.4 0.1 2.5 2 1 0 2 2 2 1 AAA domain IPT PF01745.11 EGC36355.1 - 1.7e-05 24.1 0.5 0.00034 19.8 0.0 2.7 3 0 0 3 3 3 1 Isopentenyl transferase AAA_33 PF13671.1 EGC36355.1 - 0.0032 17.3 0.2 0.03 14.2 0.0 2.5 3 0 0 3 3 3 1 AAA domain Hpr_kinase_C PF07475.7 EGC36355.1 - 0.0057 15.9 0.3 0.018 14.3 0.0 1.9 2 0 0 2 2 2 1 HPr Serine kinase C-terminal domain AAA_18 PF13238.1 EGC36355.1 - 0.008 16.4 0.0 0.008 16.4 0.0 3.6 3 1 0 3 3 3 1 AAA domain RNA_helicase PF00910.17 EGC36355.1 - 0.013 15.6 1.2 0.16 12.1 0.0 2.6 2 0 0 2 2 2 0 RNA helicase ABC_tran PF00005.22 EGC36355.1 - 0.032 14.5 0.3 0.032 14.5 0.2 2.3 2 1 0 2 2 2 0 ABC transporter AAA_22 PF13401.1 EGC36355.1 - 0.043 13.9 0.2 0.2 11.8 0.0 2.1 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGC36355.1 - 0.073 12.4 0.0 0.16 11.3 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein DUF258 PF03193.11 EGC36355.1 - 0.083 12.0 1.3 0.18 10.9 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA PF00004.24 EGC36355.1 - 0.26 11.4 1.9 0.37 10.9 0.0 2.2 3 0 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) UBX PF00789.15 EGC36356.1 - 1.7e-12 47.2 0.0 3.7e-12 46.1 0.0 1.6 1 0 0 1 1 1 1 UBX domain ubiquitin PF00240.18 EGC36356.1 - 9.6e-05 21.7 0.2 0.0045 16.3 0.0 3.4 3 1 1 4 4 4 1 Ubiquitin family Thioredoxin_7 PF13899.1 EGC36356.1 - 0.0052 16.7 0.1 0.042 13.8 0.0 2.4 3 0 0 3 3 3 1 Thioredoxin-like DUF393 PF04134.7 EGC36357.1 - 2.4e-20 73.7 0.0 3e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function, DUF393 LRR_6 PF13516.1 EGC36358.1 - 4.8e-07 29.1 27.4 0.11 12.6 0.4 8.0 8 0 0 8 8 8 4 Leucine Rich repeat DUF2251 PF10008.4 EGC36358.1 - 0.0088 16.1 0.0 2.1 8.5 0.0 2.6 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2251) Sld5 PF05916.6 EGC36359.1 - 1.5e-07 31.6 0.0 3.1e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 GINS complex protein RdRP PF05183.7 EGC36360.1 - 1.4e-127 426.8 4.8 2.1e-126 422.9 0.2 3.2 3 0 0 3 3 3 2 RNA dependent RNA polymerase Helicase_C PF00271.26 EGC36360.1 - 6.5e-18 64.3 0.1 5.6e-17 61.3 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC36360.1 - 7e-15 54.9 1.2 2.2e-14 53.2 0.0 2.5 3 0 0 3 3 3 1 DEAD/DEAH box helicase ABC_tran PF00005.22 EGC36362.1 - 1.4e-27 96.6 0.0 4e-27 95.1 0.0 1.8 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EGC36362.1 - 1.1e-21 77.3 35.8 1.7e-21 76.6 24.8 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGC36362.1 - 2.1e-12 47.5 0.3 3.2e-10 40.4 0.0 4.0 4 1 0 5 5 5 2 AAA domain SMC_N PF02463.14 EGC36362.1 - 3e-05 23.3 0.0 7.2e-05 22.1 0.0 2.0 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 EGC36362.1 - 0.041 13.3 0.3 0.088 12.2 0.2 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain IstB_IS21 PF01695.12 EGC36362.1 - 0.051 12.9 1.1 1.7 8.0 0.0 2.6 3 0 0 3 3 3 0 IstB-like ATP binding protein AAA_29 PF13555.1 EGC36362.1 - 0.073 12.6 0.4 0.17 11.4 0.3 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF4162 PF13732.1 EGC36362.1 - 0.095 13.2 4.9 0.16 12.5 0.0 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4162) ABC2_membrane_2 PF12679.2 EGC36362.1 - 2.4 6.9 21.5 7.3 5.3 11.2 2.5 2 1 1 3 3 3 0 ABC-2 family transporter protein adh_short PF00106.20 EGC36363.1 - 2.1e-19 70.0 0.0 2.5e-19 69.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36363.1 - 6.2e-10 39.2 0.0 8.4e-10 38.8 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36363.1 - 4.8e-05 23.0 0.0 6.3e-05 22.7 0.0 1.1 1 0 0 1 1 1 1 KR domain Polysacc_synt_2 PF02719.10 EGC36363.1 - 0.00018 20.4 0.0 0.00028 19.8 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NAD_binding_10 PF13460.1 EGC36363.1 - 0.003 17.5 0.0 0.0044 17.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF3236 PF11576.3 EGC36363.1 - 0.022 14.1 0.0 0.036 13.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3236) 3HCDH_N PF02737.13 EGC36363.1 - 0.038 13.6 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Epimerase PF01370.16 EGC36363.1 - 0.097 12.0 0.0 0.24 10.7 0.0 1.6 2 0 0 2 2 2 0 NAD dependent epimerase/dehydratase family Saccharop_dh PF03435.13 EGC36363.1 - 0.14 11.0 0.1 0.2 10.6 0.0 1.1 1 0 0 1 1 1 0 Saccharopine dehydrogenase Glyco_hydro_18 PF00704.23 EGC36364.1 - 2.9e-66 224.2 0.3 3.5e-66 224.0 0.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 LMP PF04778.7 EGC36364.1 - 0.26 11.0 4.1 0.26 11.0 0.1 2.6 3 0 0 3 3 3 0 LMP repeated region FNIP PF05725.7 EGC36365.1 - 1.3e-155 505.2 63.7 1.2e-15 57.1 0.1 12.0 8 2 4 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.8 EGC36365.1 - 2.4e-06 27.4 0.0 15 5.5 0.0 6.7 5 2 1 6 6 6 1 Phage minor tail protein DUF3216 PF11505.3 EGC36365.1 - 0.21 11.3 0.0 35 4.2 0.0 4.0 4 2 0 4 4 4 0 Protein of unknown function (DUF3216) Shigella_OspC PF06128.6 EGC36365.1 - 6.8 6.0 11.7 10 5.4 0.1 4.7 3 2 1 5 5 5 0 Shigella flexneri OspC protein RNase_T PF00929.19 EGC36366.1 - 2e-05 24.9 0.0 2.5e-05 24.6 0.0 1.1 1 0 0 1 1 1 1 Exonuclease Acyl_transf_1 PF00698.16 EGC36367.1 - 7.4e-45 153.6 0.0 1.2e-44 152.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain ketoacyl-synt PF00109.21 EGC36367.1 - 7.5e-40 137.0 0.1 1.9e-36 125.8 0.0 2.5 2 0 0 2 2 2 2 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC36367.1 - 3.5e-29 101.0 0.0 6.3e-29 100.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC36367.1 - 3.3e-23 82.0 0.0 3.3e-23 82.0 0.0 4.2 3 0 0 3 3 2 1 Methyltransferase domain KR PF08659.5 EGC36367.1 - 3.4e-21 75.7 0.0 6.3e-21 74.8 0.0 1.4 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC36367.1 - 1.7e-19 70.1 0.0 2.4e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC36367.1 - 3.1e-14 53.2 0.0 5.7e-14 52.3 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC36367.1 - 4.2e-08 34.1 0.0 8.9e-08 33.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC36367.1 - 2.8e-07 30.2 0.1 5.8e-07 29.2 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC36367.1 - 6e-07 29.8 0.1 4.8e-06 26.9 0.0 2.6 3 0 0 3 3 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36367.1 - 3.1e-06 27.0 0.0 8.9e-06 25.5 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC36367.1 - 2.2e-05 24.6 0.1 6.5e-05 23.1 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC36367.1 - 0.00022 20.3 0.0 0.00054 19.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain adh_short PF00106.20 EGC36368.1 - 2.4e-19 69.8 0.0 2.9e-19 69.5 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36368.1 - 7.9e-08 32.3 0.0 1.1e-07 31.9 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGC36368.1 - 9.6e-05 21.4 0.0 0.00015 20.7 0.0 1.4 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein KR PF08659.5 EGC36368.1 - 0.00028 20.5 0.0 0.00039 20.1 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC36368.1 - 0.0062 16.5 0.0 0.0086 16.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF3236 PF11576.3 EGC36368.1 - 0.0088 15.4 0.0 0.016 14.6 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3236) 3HCDH_N PF02737.13 EGC36368.1 - 0.025 14.2 0.2 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain Glyco_hydro_18 PF00704.23 EGC36369.1 - 2.4e-69 234.3 0.5 2.9e-69 234.1 0.3 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Helicase_C PF00271.26 EGC36370.1 - 2.5e-13 49.6 0.0 6.8e-13 48.2 0.0 1.8 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-RING_2 PF13639.1 EGC36370.1 - 1.3e-07 31.3 4.2 8.3e-07 28.7 1.5 2.5 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_4 PF15227.1 EGC36370.1 - 2.2e-07 30.6 7.4 7.3e-07 28.9 2.7 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4_2 PF13923.1 EGC36370.1 - 2.3e-07 30.7 8.1 3.7e-07 30.0 2.6 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC36370.1 - 8.2e-07 28.5 8.4 1.5e-06 27.7 3.5 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC36370.1 - 1.3e-06 28.0 6.7 9.7e-06 25.2 2.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC36370.1 - 2.5e-06 27.0 5.5 6.8e-05 22.4 1.3 2.4 2 0 0 2 2 2 2 Zinc finger, C3HC4 type (RING finger) SNF2_N PF00176.18 EGC36370.1 - 0.00085 18.1 0.1 0.002 16.9 0.1 1.7 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_UBOX PF13445.1 EGC36370.1 - 0.0011 18.6 2.2 0.0011 18.6 1.5 2.8 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGC36370.1 - 0.23 11.2 4.0 0.13 12.0 0.6 2.3 3 0 0 3 3 3 0 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGC36370.1 - 1.3 9.2 6.2 22 5.2 3.0 3.0 2 1 0 2 2 2 0 RING-H2 zinc finger SNF2_N PF00176.18 EGC36371.1 - 4.1e-52 176.8 0.1 4.5e-52 176.7 0.1 1.0 1 0 0 1 1 1 1 SNF2 family N-terminal domain DEAD PF00270.24 EGC36371.1 - 2.5e-05 23.8 0.0 5.8e-05 22.6 0.0 1.6 1 1 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGC36371.1 - 0.00023 21.0 0.0 0.00035 20.4 0.0 1.3 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit Ribosomal_S11 PF00411.14 EGC36372.1 - 5.1e-37 126.4 0.9 6.6e-37 126.0 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S11 Aa_trans PF01490.13 EGC36373.1 - 4.6e-17 61.5 34.1 1.1e-16 60.3 23.6 1.7 1 1 0 1 1 1 1 Transmembrane amino acid transporter protein E1-E2_ATPase PF00122.15 EGC36373.1 - 1 8.3 4.6 0.49 9.3 0.0 2.6 2 1 0 2 2 2 0 E1-E2 ATPase Mob1_phocein PF03637.12 EGC36374.1 - 2.1e-76 255.4 0.2 2.6e-76 255.1 0.1 1.1 1 0 0 1 1 1 1 Mob1/phocein family CBM_5_12_2 PF14600.1 EGC36375.1 - 0.0092 15.5 0.3 0.019 14.6 0.2 1.6 1 0 0 1 1 1 1 Cellulose-binding domain ThiF PF00899.16 EGC36376.1 - 2.9e-36 124.2 0.0 2.9e-36 124.2 0.0 1.8 2 0 0 2 2 2 1 ThiF family MoeZ_MoeB PF05237.8 EGC36376.1 - 0.00013 21.4 0.3 0.00044 19.7 0.1 2.0 2 0 0 2 2 2 1 MoeZ/MoeB domain 2-Hacid_dh_C PF02826.14 EGC36376.1 - 0.00032 19.9 0.0 0.00052 19.2 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGC36376.1 - 0.004 17.1 0.0 0.018 15.0 0.0 2.0 2 0 0 2 2 2 1 TrkA-N domain ApbA PF02558.11 EGC36376.1 - 0.016 14.6 0.3 0.042 13.2 0.0 1.9 2 1 0 2 2 2 0 Ketopantoate reductase PanE/ApbA UDPG_MGDP_dh_N PF03721.9 EGC36376.1 - 0.02 14.3 0.1 0.037 13.3 0.1 1.5 1 0 0 1 1 1 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain ECSIT PF06239.6 EGC36376.1 - 0.047 12.5 0.0 0.1 11.4 0.0 1.5 1 0 0 1 1 1 0 Evolutionarily conserved signalling intermediate in Toll pathway Shikimate_DH PF01488.15 EGC36376.1 - 0.05 13.7 0.0 0.12 12.4 0.0 1.7 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF4320 PF14208.1 EGC36376.1 - 0.23 11.4 2.1 2.3 8.2 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4320) LRR_4 PF12799.2 EGC36377.1 - 8.9e-28 95.4 82.9 1e-05 24.9 1.5 12.5 6 6 8 14 14 14 13 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC36377.1 - 1.7e-22 78.9 61.8 1.7e-06 27.6 6.8 9.4 6 5 4 10 10 10 9 Leucine rich repeat LRR_1 PF00560.28 EGC36377.1 - 1.1e-06 27.8 68.9 0.27 11.3 0.4 16.5 15 4 2 17 17 17 4 Leucine Rich Repeat LRR_9 PF14580.1 EGC36377.1 - 8.9e-06 25.3 18.9 0.006 16.1 1.7 5.2 5 0 0 5 5 5 3 Leucine-rich repeat LRR_7 PF13504.1 EGC36377.1 - 0.018 15.1 53.7 0.091 13.0 0.6 15.4 17 0 0 17 17 17 0 Leucine rich repeat LRR_6 PF13516.1 EGC36377.1 - 0.019 14.9 62.0 0.72 10.0 0.2 14.3 14 1 1 15 15 15 0 Leucine Rich repeat zf-RING_2 PF13639.1 EGC36378.1 - 3.9e-09 36.2 11.2 3.9e-09 36.2 7.8 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC36378.1 - 1e-06 28.7 6.3 3.1e-06 27.2 4.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC36378.1 - 1.2e-06 28.0 8.1 3e-06 26.8 5.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36378.1 - 4.9e-05 23.2 13.8 0.00013 21.9 9.6 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC36378.1 - 0.00022 20.8 14.0 0.00022 20.8 9.7 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EGC36378.1 - 0.001 19.0 38.9 0.001 19.0 26.9 2.2 1 1 1 2 2 2 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.1 EGC36378.1 - 0.0059 16.2 12.5 0.0059 16.2 8.7 2.1 3 0 0 3 3 3 1 zinc-RING finger domain Baculo_RING PF05883.6 EGC36378.1 - 0.021 14.6 6.1 0.058 13.2 4.3 1.8 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EGC36378.1 - 0.038 13.8 13.3 0.11 12.3 9.2 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC36378.1 - 0.48 10.2 5.3 1.4 8.8 3.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Activator_LAG-3 PF11498.3 EGC36380.1 - 2.3 6.8 17.9 3.3 6.3 12.4 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Med3 PF11593.3 EGC36380.1 - 3.9 6.6 10.1 6.6 5.8 7.0 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal Zip PF02535.17 EGC36381.1 - 2.9 6.8 11.3 7.4 5.4 5.9 2.0 2 0 0 2 2 2 0 ZIP Zinc transporter FNIP PF05725.7 EGC36382.1 - 8.1e-42 140.9 40.3 2.4e-08 33.7 0.1 9.4 4 3 5 10 10 10 9 FNIP Repeat DUF1769 PF08588.5 EGC36382.1 - 2.4 8.1 6.4 4.1 7.4 0.1 4.1 5 1 1 6 6 6 0 Protein of unknown function (DUF1769) WD40 PF00400.27 EGC36383.1 - 1.5e-122 395.5 81.6 4.4e-11 42.2 1.3 19.9 21 0 0 21 21 21 17 WD domain, G-beta repeat TROVE PF05731.6 EGC36383.1 - 1.5e-64 218.1 1.8 1e-61 208.8 1.3 2.6 1 1 0 1 1 1 1 TROVE domain DUF4062 PF13271.1 EGC36383.1 - 2.5e-09 37.0 0.1 2.5e-08 33.8 0.0 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4062) AAA_22 PF13401.1 EGC36383.1 - 7.3e-07 29.3 0.0 4.7e-06 26.7 0.0 2.4 2 0 0 2 2 1 1 AAA domain NACHT PF05729.7 EGC36383.1 - 8.1e-07 28.8 0.0 2.3e-06 27.3 0.0 1.8 1 0 0 1 1 1 1 NACHT domain AAA_16 PF13191.1 EGC36383.1 - 6.3e-06 26.2 0.0 3.6e-05 23.8 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain PD40 PF07676.7 EGC36383.1 - 9.4e-06 25.1 0.3 2.6 7.8 0.0 5.3 5 0 0 5 5 5 1 WD40-like Beta Propeller Repeat AAA PF00004.24 EGC36383.1 - 0.0016 18.6 0.5 0.064 13.4 0.2 3.5 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) ABC_tran PF00005.22 EGC36383.1 - 0.016 15.4 0.1 0.082 13.2 0.1 2.3 1 0 0 1 1 1 0 ABC transporter Miro PF08477.8 EGC36383.1 - 0.017 15.6 1.0 0.12 12.8 0.0 3.2 3 0 0 3 3 2 0 Miro-like protein FtsK_SpoIIIE PF01580.13 EGC36383.1 - 0.13 11.7 0.0 8.5 5.7 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family ArgK PF03308.11 EGC36383.1 - 0.47 9.1 0.2 2.2 6.9 0.0 2.0 2 0 0 2 2 2 0 ArgK protein DEAD PF00270.24 EGC36384.1 - 3.3e-44 150.3 0.0 1.2e-42 145.2 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC36384.1 - 8.6e-24 83.2 0.1 2.5e-23 81.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC36384.1 - 1.3e-06 28.4 0.7 3.9e-05 23.5 0.0 3.3 3 1 0 3 3 3 1 Type III restriction enzyme, res subunit CMS1 PF14617.1 EGC36384.1 - 0.011 14.7 0.0 0.011 14.7 0.0 1.9 2 0 0 2 2 2 0 U3-containing 90S pre-ribosomal complex subunit AAA_19 PF13245.1 EGC36384.1 - 0.047 13.4 0.0 0.17 11.6 0.0 2.0 1 0 0 1 1 1 0 Part of AAA domain Ras PF00071.17 EGC36385.1 - 4.6e-59 198.4 0.0 5.4e-59 198.1 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC36385.1 - 7.1e-20 71.6 0.1 1.5e-19 70.6 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC36385.1 - 2.5e-10 39.8 0.0 2.9e-10 39.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC36385.1 - 1.4e-08 34.4 0.1 3.2e-08 33.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC36385.1 - 0.0035 17.2 0.0 0.0055 16.6 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGC36385.1 - 0.015 14.4 0.0 0.019 14.1 0.0 1.1 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EGC36385.1 - 0.12 11.6 0.0 0.29 10.4 0.0 1.6 2 0 0 2 2 2 0 Ferrous iron transport protein B FNIP PF05725.7 EGC36386.1 - 8.4e-35 118.4 75.8 1.3e-08 34.6 2.2 11.4 8 3 3 11 11 11 11 FNIP Repeat DNA_ligase_A_M PF01068.16 EGC36387.1 - 7e-43 146.3 0.0 1.5e-42 145.2 0.0 1.6 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGC36387.1 - 2e-37 128.7 0.4 4.4e-37 127.5 0.3 1.6 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGC36387.1 - 1.6e-18 66.8 0.0 3.8e-18 65.6 0.0 1.7 1 0 0 1 1 1 1 ATP dependent DNA ligase C terminal region BRCT PF00533.21 EGC36387.1 - 1.2e-15 57.4 3.4 5.8e-09 35.9 0.4 3.1 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain DNA_ligase_IV PF11411.3 EGC36387.1 - 1.3e-12 47.1 0.4 2.7e-12 46.1 0.3 1.6 1 0 0 1 1 1 1 DNA ligase IV PTCB-BRCT PF12738.2 EGC36387.1 - 7.1e-06 25.7 0.0 0.041 13.7 0.0 2.8 2 1 0 2 2 2 2 twin BRCT domain YfbU PF03887.9 EGC36387.1 - 0.0019 17.7 0.7 0.0095 15.5 0.0 2.3 2 0 0 2 2 2 1 YfbU domain TIG PF01833.19 EGC36388.1 - 0.00022 21.1 3.6 0.00022 21.1 2.5 4.9 3 1 1 4 4 4 2 IPT/TIG domain adh_short PF00106.20 EGC36389.1 - 5e-24 85.0 0.0 6.2e-24 84.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36389.1 - 1.7e-14 54.2 0.0 2.3e-14 53.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36389.1 - 5.5e-07 29.4 0.0 8.7e-07 28.7 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC36389.1 - 2.4e-06 26.8 0.1 1.4e-05 24.4 0.1 1.9 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC36389.1 - 2.7e-05 23.7 0.0 4.4e-05 23.0 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC36389.1 - 7.3e-05 22.8 0.0 0.00011 22.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC36389.1 - 0.00041 19.3 0.0 0.00071 18.5 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC36389.1 - 0.0037 16.1 0.0 0.0047 15.8 0.0 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein WD-3 PF09765.4 EGC36390.1 - 9.6e-35 120.2 5.5 2.7e-25 89.2 0.8 3.1 2 1 1 3 3 3 2 WD-repeat region FANCL_C PF11793.3 EGC36390.1 - 1.1e-23 82.9 4.0 3e-23 81.5 2.7 1.8 1 0 0 1 1 1 1 FANCL C-terminal domain zf-rbx1 PF12678.2 EGC36390.1 - 1.5e-05 25.0 2.4 4.9e-05 23.3 1.8 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger RWD PF05773.17 EGC36390.1 - 0.016 15.0 2.4 0.051 13.4 1.6 2.0 1 1 0 1 1 1 0 RWD domain zf-RING_2 PF13639.1 EGC36390.1 - 0.025 14.3 14.5 0.085 12.7 8.0 2.8 2 1 0 2 2 2 0 Ring finger domain zf-Apc11 PF12861.2 EGC36390.1 - 0.13 12.0 2.8 0.46 10.3 1.9 1.9 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING-like PF08746.6 EGC36390.1 - 0.21 11.5 3.1 0.21 11.6 0.2 2.3 2 0 0 2 2 2 0 RING-like domain zf-C3HC4_2 PF13923.1 EGC36390.1 - 4.6 7.3 12.7 0.3 11.1 2.5 3.0 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) DUF2145 PF09916.4 EGC36391.1 - 0.093 12.2 0.4 0.16 11.4 0.3 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2145) Atg8 PF02991.11 EGC36392.1 - 3.6e-41 139.3 0.2 4.2e-41 139.1 0.2 1.0 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGC36392.1 - 7e-07 29.3 0.0 9.3e-07 28.9 0.0 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 AA_permease_2 PF13520.1 EGC36393.1 - 3.3e-38 131.3 51.8 4e-38 131.0 35.9 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC36393.1 - 7.8e-24 83.8 43.6 1.1e-23 83.3 30.2 1.1 1 0 0 1 1 1 1 Amino acid permease Tetraspannin PF00335.15 EGC36394.1 - 0.0058 15.9 8.2 0.0099 15.1 5.7 1.3 1 0 0 1 1 1 1 Tetraspanin family Acetyltransf_CG PF14542.1 EGC36396.1 - 7e-17 61.0 0.0 8.2e-17 60.8 0.0 1.1 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Cytokin_check_N PF10407.4 EGC36396.1 - 0.16 11.6 0.4 0.25 10.9 0.2 1.4 1 1 0 1 1 1 0 Cdc14 phosphatase binding protein N-terminus Apolipoprotein PF01442.13 EGC36397.1 - 1.1e-06 28.3 11.6 0.00017 21.2 4.9 2.4 1 1 1 2 2 2 2 Apolipoprotein A1/A4/E domain DUF883 PF05957.8 EGC36397.1 - 9.1e-06 25.9 19.8 0.09 13.1 0.2 4.8 1 1 3 4 4 4 2 Bacterial protein of unknown function (DUF883) Phasin PF05597.6 EGC36397.1 - 0.0075 16.0 29.2 0.017 14.8 5.2 4.5 1 1 3 4 4 4 2 Poly(hydroxyalcanoate) granule associated protein (phasin) SpoU_sub_bind PF08032.7 EGC36397.1 - 0.083 13.0 0.2 2.7 8.2 0.0 3.0 2 1 0 2 2 2 0 RNA 2'-O ribose methyltransferase substrate binding YtxH PF12732.2 EGC36397.1 - 0.19 12.1 45.1 4.5 7.6 0.5 6.1 3 2 1 4 4 4 0 YtxH-like protein ATP-synt_B PF00430.13 EGC36397.1 - 0.22 11.3 31.3 2.2 8.0 1.8 4.9 2 1 2 4 4 4 0 ATP synthase B/B' CF(0) RGS PF00615.14 EGC36397.1 - 1.1 9.3 11.5 9.5 6.3 8.0 2.4 1 1 0 1 1 1 0 Regulator of G protein signaling domain Hormone_1 PF00103.15 EGC36397.1 - 1.2 8.3 8.4 3.7 6.8 0.2 3.4 1 1 2 3 3 3 0 Somatotropin hormone family Tape_meas_lam_C PF09718.5 EGC36397.1 - 3.2 7.7 8.3 25 4.8 0.0 3.8 2 2 3 5 5 5 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) Lambda_tail_I PF06805.7 EGC36398.1 - 8e-05 22.3 0.0 2.5 7.9 0.0 3.5 3 0 0 3 3 3 2 Bacteriophage lambda tail assembly protein I DOMON PF03351.12 EGC36398.1 - 0.00062 19.6 1.3 9.5 6.1 0.0 4.8 4 0 0 4 4 4 1 DOMON domain Alpha-2-MRAP_C PF06401.6 EGC36398.1 - 0.021 14.6 3.1 9 6.0 0.0 3.8 4 0 0 4 4 4 0 Alpha-2-macroglobulin RAP, C-terminal domain DUF3022 PF11226.3 EGC36398.1 - 0.073 12.9 0.0 8.4 6.3 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3022) Cep57_MT_bd PF06657.8 EGC36398.1 - 0.075 12.9 2.3 2.3 8.1 0.0 3.9 5 0 0 5 5 5 0 Centrosome microtubule-binding domain of Cep57 AvrPtoB-E3_ubiq PF09046.5 EGC36398.1 - 0.51 10.3 6.4 9.6 6.2 0.0 4.3 5 0 0 5 5 5 0 AvrPtoB E3 ubiquitin ligase Inhibitor_I53 PF11714.3 EGC36398.1 - 0.77 9.7 3.0 40 4.3 0.0 3.3 4 0 0 4 4 4 0 Thrombin inhibitor Madanin Peptidase_S74 PF13884.1 EGC36398.1 - 7.6 6.7 11.5 27 4.9 0.2 4.2 5 0 0 5 5 5 0 Chaperone of endosialidase Sterile PF03015.14 EGC36398.1 - 8.4 6.7 14.3 16 5.7 0.0 5.4 6 0 0 6 6 6 0 Male sterility protein His_Phos_1 PF00300.17 EGC36400.1 - 3.5e-21 75.9 0.0 4.6e-21 75.5 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) 2OG-FeII_Oxy PF03171.15 EGC36401.1 - 9.3e-24 83.6 0.0 2e-23 82.5 0.0 1.6 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DIOX_N PF14226.1 EGC36401.1 - 5.4e-22 78.5 0.0 1.1e-21 77.5 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal FNIP PF05725.7 EGC36402.1 - 8.3e-33 112.0 11.4 9.2e-09 35.1 0.3 5.7 3 1 2 5 5 5 5 FNIP Repeat DUF128 PF01995.11 EGC36402.1 - 0.036 13.0 0.1 0.053 12.4 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF128 eIF3_N PF09440.5 EGC36403.1 - 4.8e-18 65.6 3.5 2.3e-16 60.1 2.4 2.6 1 1 1 2 2 2 1 eIF3 subunit 6 N terminal domain PCI PF01399.22 EGC36403.1 - 7.9e-13 48.6 0.2 3.1e-12 46.7 0.2 2.0 1 0 0 1 1 1 1 PCI domain Mucin PF01456.12 EGC36403.1 - 0.0033 17.1 45.7 0.0065 16.2 8.2 2.2 2 0 0 2 2 2 2 Mucin-like glycoprotein DUF3439 PF11921.3 EGC36403.1 - 0.023 14.4 32.6 0.076 12.7 6.4 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) OmpH PF03938.9 EGC36403.1 - 0.029 14.2 12.4 0.037 13.9 5.3 2.6 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) Vfa1 PF08432.5 EGC36403.1 - 0.19 11.7 22.5 0.11 12.4 9.4 2.3 2 0 0 2 2 2 0 AAA-ATPase Vps4-associated protein 1 DUF2956 PF11169.3 EGC36403.1 - 0.25 11.3 20.5 0.29 11.0 3.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2956) Iron_permease PF04120.7 EGC36403.1 - 1.2 8.7 9.2 3 7.4 0.1 2.6 2 0 0 2 2 2 0 Low affinity iron permease Rtf2 PF04641.7 EGC36403.1 - 1.3 8.1 16.1 0.37 9.9 5.3 2.3 2 0 0 2 2 2 0 Rtf2 RING-finger Ctr PF04145.10 EGC36403.1 - 1.6 8.7 7.4 5.1 7.1 0.9 2.6 2 0 0 2 2 2 0 Ctr copper transporter family Menin PF05053.8 EGC36403.1 - 2.4 6.2 15.2 1.5 6.8 1.9 2.1 2 0 0 2 2 2 0 Menin DUF702 PF05142.7 EGC36403.1 - 5.4 7.1 14.8 5.7 7.0 2.7 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Med3 PF11593.3 EGC36403.1 - 7 5.7 33.6 0.025 13.8 6.2 2.3 2 0 0 2 2 2 0 Mediator complex subunit 3 fungal APC_CDC26 PF10471.4 EGC36403.1 - 9.5 7.0 23.2 0.38 11.5 5.8 2.9 3 0 0 3 3 2 0 Anaphase-promoting complex APC subunit 1 UBA_4 PF14555.1 EGC36404.1 - 0.0027 17.1 0.0 0.0027 17.1 0.0 2.0 2 1 0 2 2 2 1 UBA-like domain TAP_C PF03943.8 EGC36404.1 - 0.0031 16.9 0.2 0.0057 16.0 0.1 1.4 1 0 0 1 1 1 1 TAP C-terminal domain DUF912 PF06024.7 EGC36404.1 - 0.059 13.4 4.5 0.097 12.7 3.1 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) EVI2A PF05399.6 EGC36404.1 - 0.61 9.2 7.4 0.72 9.0 5.1 1.1 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) Menin PF05053.8 EGC36404.1 - 4 5.4 7.7 3.8 5.5 5.4 1.1 1 0 0 1 1 1 0 Menin OmpH PF03938.9 EGC36405.1 - 0.28 11.1 5.3 0.19 11.6 1.1 2.1 2 0 0 2 2 2 0 Outer membrane protein (OmpH-like) ATP-synt_B PF00430.13 EGC36405.1 - 1.3 8.8 10.2 15 5.4 0.0 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) Peptidase_C26 PF07722.8 EGC36406.1 - 2e-36 125.4 0.0 2.6e-36 125.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase C26 GATase PF00117.23 EGC36406.1 - 4.8e-12 45.7 0.0 8.3e-12 44.9 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Usp PF00582.21 EGC36407.1 - 6.5e-17 62.0 0.0 7.3e-17 61.8 0.0 1.0 1 0 0 1 1 1 1 Universal stress protein family Antimicrobial19 PF08225.6 EGC36407.1 - 0.031 13.6 0.3 0.059 12.7 0.2 1.5 1 0 0 1 1 1 0 Pseudin antimicrobial peptide DeoRC PF00455.17 EGC36407.1 - 0.053 13.1 0.0 0.085 12.4 0.0 1.3 1 0 0 1 1 1 0 DeoR C terminal sensor domain BROMI PF14961.1 EGC36408.1 - 0.023 11.8 1.0 0.026 11.6 0.7 1.0 1 0 0 1 1 1 0 Broad-minded protein DUF4557 PF15101.1 EGC36408.1 - 0.15 11.8 2.7 0.16 11.8 1.9 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) Ion_trans PF00520.26 EGC36409.1 - 0.032 13.4 0.0 0.032 13.4 0.0 1.1 1 0 0 1 1 1 0 Ion transport protein AAA_23 PF13476.1 EGC36409.1 - 0.2 11.9 15.3 0.33 11.2 10.6 1.4 1 0 0 1 1 1 0 AAA domain PAT1 PF09770.4 EGC36409.1 - 0.62 8.2 32.7 0.75 7.9 22.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 eIF-3_zeta PF05091.7 EGC36409.1 - 6.5 5.2 19.6 7.9 4.9 13.6 1.0 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Zip PF02535.17 EGC36409.1 - 8.8 5.2 6.3 15 4.4 4.4 1.5 1 1 0 1 1 1 0 ZIP Zinc transporter DUF1900 PF08954.6 EGC36410.1 - 3.3e-07 29.9 0.0 3.9e-07 29.6 0.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF1900) PEPcase_2 PF14010.1 EGC36411.1 - 0.012 13.8 2.7 0.018 13.3 1.9 1.3 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase CAF-1_p150 PF11600.3 EGC36411.1 - 1.6 8.0 19.7 2.4 7.4 13.7 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ISG65-75 PF11727.3 EGC36411.1 - 1.8 7.5 17.7 0.052 12.5 4.9 2.1 1 1 0 2 2 2 0 Invariant surface glycoprotein adh_short PF00106.20 EGC36413.1 - 1.8e-27 96.2 0.0 2.2e-27 95.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36413.1 - 6.1e-24 85.1 0.0 7.6e-24 84.8 0.0 1.0 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36413.1 - 1.6e-12 47.4 0.0 2.3e-12 46.9 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC36413.1 - 9.9e-05 22.4 0.0 0.004 17.1 0.0 2.1 1 1 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGC36413.1 - 0.0019 17.4 0.1 0.0032 16.6 0.1 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC36413.1 - 0.0071 15.8 0.0 0.01 15.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_Gly3P_dh_N PF01210.18 EGC36413.1 - 0.13 12.0 0.0 0.25 11.0 0.0 1.5 1 0 0 1 1 1 0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus RabGAP-TBC PF00566.13 EGC36414.1 - 1.9e-53 181.0 0.2 1.9e-53 181.0 0.1 3.6 4 0 0 4 4 4 1 Rab-GTPase-TBC domain GRAM PF02893.15 EGC36414.1 - 2.9e-11 42.7 7.8 7e-06 25.4 0.6 2.7 2 0 0 2 2 2 2 GRAM domain Vps36_ESCRT-II PF11605.3 EGC36414.1 - 0.0098 15.6 0.0 0.065 13.0 0.0 2.4 2 0 0 2 2 2 1 Vacuolar protein sorting protein 36 Vps36 Laminin_EGF PF00053.19 EGC36415.1 - 1.5e-09 37.5 89.3 0.014 15.2 11.0 5.6 3 2 2 5 5 5 4 Laminin EGF-like (Domains III and V) DUF4399 PF14347.1 EGC36415.1 - 3.8e-06 26.8 0.9 1.1 9.3 0.0 6.9 9 0 0 9 9 9 2 Domain of unknown function (DUF4399) EGF_2 PF07974.8 EGC36415.1 - 0.0048 17.0 10.4 0.0048 17.0 7.2 7.5 6 1 0 6 6 6 3 EGF-like domain YL1 PF05764.8 EGC36415.1 - 3.2 7.2 6.7 4.9 6.6 4.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein Peptidase_S8 PF00082.17 EGC36416.1 - 2.5e-36 125.2 0.7 2.5e-36 125.2 0.5 2.3 3 0 0 3 3 3 1 Subtilase family Peroxin-13_N PF04088.8 EGC36416.1 - 1.1 9.1 5.8 0.19 11.6 0.1 2.3 2 0 0 2 2 2 0 Peroxin 13, N-terminal region EGF_2 PF07974.8 EGC36416.1 - 8.8 6.5 11.3 0.4 10.8 2.5 2.6 2 1 0 2 2 2 0 EGF-like domain Erf4 PF10256.4 EGC36417.1 - 4.7e-05 23.2 1.9 0.0001 22.1 0.1 2.0 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Activator_LAG-3 PF11498.3 EGC36417.1 - 0.036 12.8 15.7 0.045 12.4 10.9 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 YABBY PF04690.8 EGC36417.1 - 0.12 12.5 5.9 0.034 14.3 1.9 1.6 2 0 0 2 2 2 0 YABBY protein DUF4538 PF15061.1 EGC36417.1 - 0.27 10.5 0.1 0.27 10.5 0.1 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4538) RED_N PF07808.8 EGC36417.1 - 0.53 9.4 9.7 0.59 9.3 6.7 1.2 1 0 0 1 1 1 0 RED-like protein N-terminal region Mitofilin PF09731.4 EGC36417.1 - 0.88 8.1 6.6 1 7.9 4.6 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein XLF PF09302.6 EGC36417.1 - 1.3 8.7 7.2 3.3 7.4 5.0 1.9 1 1 0 1 1 1 0 XLF (XRCC4-like factor) BAF1_ABF1 PF04684.8 EGC36417.1 - 6.9 5.3 11.6 7.8 5.2 8.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Glyco_hydro_25 PF01183.15 EGC36419.1 - 1.4e-09 38.0 1.0 1.8e-09 37.6 0.7 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 adh_short PF00106.20 EGC36420.1 - 1.4e-22 80.3 0.0 1.7e-22 80.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC36420.1 - 1.5e-08 34.5 0.0 1.9e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC36420.1 - 0.00017 21.4 0.0 0.00024 20.9 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Polysacc_synt_2 PF02719.10 EGC36420.1 - 0.00022 20.2 0.0 0.00037 19.4 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Eno-Rase_NADH_b PF12242.3 EGC36420.1 - 0.0038 16.9 0.0 0.0083 15.8 0.0 1.5 1 0 0 1 1 1 1 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EGC36420.1 - 0.097 12.0 0.0 0.12 11.7 0.0 1.3 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC36420.1 - 0.12 12.4 0.0 0.17 11.8 0.0 1.3 1 0 0 1 1 1 0 NADH(P)-binding RUN PF02759.14 EGC36421.1 - 1.6e-22 79.6 2.1 4.2e-22 78.3 0.0 2.9 3 0 0 3 3 3 1 RUN domain DUF3439 PF11921.3 EGC36421.1 - 0.47 10.1 12.4 1.6 8.4 8.6 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) HEAT_2 PF13646.1 EGC36422.1 - 3e-14 53.0 0.0 4.8e-05 23.5 0.0 4.2 3 1 2 5 5 5 4 HEAT repeats HEAT PF02985.17 EGC36422.1 - 5.9e-14 50.8 1.2 0.23 11.6 0.0 7.5 8 0 0 8 8 8 4 HEAT repeat HEAT_EZ PF13513.1 EGC36422.1 - 0.0069 16.8 0.0 65 4.2 0.0 4.8 4 1 1 5 5 5 0 HEAT-like repeat PP-binding PF00550.20 EGC36423.1 - 3e-11 43.3 0.0 3.9e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3194 PF11419.3 EGC36423.1 - 0.1 12.8 0.9 0.13 12.4 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3194) Chromo PF00385.19 EGC36424.1 - 0.0047 16.5 0.0 0.008 15.8 0.0 1.3 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tetraspannin PF00335.15 EGC36425.1 - 0.68 9.1 4.6 1.6 7.9 3.2 1.7 1 1 0 1 1 1 0 Tetraspanin family SOCS PF12610.3 EGC36425.1 - 0.69 10.2 6.7 1.7 9.0 0.0 3.0 2 1 1 3 3 3 0 Suppressor of cytokine signalling AAT PF03417.11 EGC36426.1 - 4.9e-10 39.2 0.1 5.7e-09 35.7 0.1 2.1 1 1 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase RGS PF00615.14 EGC36426.1 - 0.063 13.3 0.2 0.22 11.6 0.1 2.0 1 0 0 1 1 1 0 Regulator of G protein signaling domain RAI1 PF08652.6 EGC36427.1 - 1.5e-16 59.9 0.1 1.5e-16 59.9 0.1 2.1 2 0 0 2 2 2 1 RAI1 like PD-(D/E)XK nuclease Rsc14 PF08586.5 EGC36427.1 - 0.44 11.0 6.8 1.3 9.4 0.2 2.6 2 0 0 2 2 2 0 RSC complex, Rsc14/Ldb7 subunit AdoMet_MTase PF07757.8 EGC36428.1 - 2.8e-37 127.2 0.1 5.8e-37 126.2 0.1 1.5 1 0 0 1 1 1 1 Predicted AdoMet-dependent methyltransferase Methyltransf_23 PF13489.1 EGC36428.1 - 3.6e-06 26.7 0.1 1.9e-05 24.4 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC36428.1 - 0.0041 16.7 1.1 0.03 13.9 0.0 2.5 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36428.1 - 0.011 16.3 0.0 0.026 15.0 0.0 1.7 1 0 0 1 1 1 0 Methyltransferase domain MetW PF07021.7 EGC36428.1 - 0.013 14.9 0.1 0.028 13.7 0.0 1.5 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_32 PF13679.1 EGC36428.1 - 0.021 14.5 0.1 0.071 12.7 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36428.1 - 0.034 14.6 0.0 0.35 11.3 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain MTS PF05175.9 EGC36428.1 - 0.094 12.0 0.0 0.17 11.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_12 PF08242.7 EGC36428.1 - 1.2 9.6 0.0 1.2 9.6 0.0 4.5 5 0 0 5 5 5 0 Methyltransferase domain Mito_carr PF00153.22 EGC36429.1 - 5.7e-71 234.2 2.8 2.1e-27 94.6 0.1 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGC36429.1 - 0.0017 18.1 0.1 0.87 9.4 0.0 2.6 3 0 0 3 3 3 2 UcrQ family NIF3 PF01784.13 EGC36430.1 - 3.4e-67 226.5 0.1 4.7e-67 226.0 0.0 1.1 1 0 0 1 1 1 1 NIF3 (NGG1p interacting factor 3) CBS PF00571.23 EGC36431.1 - 2.4e-23 81.6 9.6 2.2e-07 30.5 0.1 4.2 4 0 0 4 4 4 4 CBS domain P4Ha_N PF08336.6 EGC36432.1 - 0.0018 18.1 1.5 0.0068 16.2 0.8 2.1 2 0 0 2 2 2 1 Prolyl 4-Hydroxylase alpha-subunit, N-terminal region Ycf1 PF05758.7 EGC36433.1 - 0.0042 14.9 10.2 0.006 14.3 7.1 1.4 1 1 0 1 1 1 1 Ycf1 Tom37_C PF11801.3 EGC36433.1 - 0.013 15.3 1.0 0.023 14.5 0.7 1.3 1 0 0 1 1 1 0 Tom37 C-terminal domain ATP11 PF06644.6 EGC36433.1 - 0.063 12.7 4.8 0.09 12.2 3.3 1.1 1 0 0 1 1 1 0 ATP11 protein Peptidase_S8 PF00082.17 EGC36434.1 - 1.1e-44 152.6 0.9 1.1e-44 152.6 0.6 1.7 2 0 0 2 2 2 1 Subtilase family EGF_2 PF07974.8 EGC36434.1 - 1.5 9.0 16.1 5.2 7.3 11.2 2.0 1 0 0 1 1 1 0 EGF-like domain Tubulin PF00091.20 EGC36435.1 - 5.5e-71 238.8 0.0 1.1e-70 237.7 0.0 1.5 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGC36435.1 - 7.4e-48 161.7 0.1 1.2e-47 161.0 0.1 1.4 1 0 0 1 1 1 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGC36435.1 - 2.4e-06 27.5 1.5 3e-06 27.2 0.0 1.9 2 0 0 2 2 2 1 Misato Segment II tubulin-like domain Tubulin_3 PF14881.1 EGC36435.1 - 0.00043 19.7 0.0 0.0011 18.5 0.0 1.7 1 0 0 1 1 1 1 Tubulin domain Tetraspannin PF00335.15 EGC36436.1 - 7.6e-05 22.0 8.2 8.1e-05 22.0 5.3 1.3 1 1 0 1 1 1 1 Tetraspanin family Erf4 PF10256.4 EGC36436.1 - 0.001 18.9 12.8 0.0012 18.6 1.3 2.3 1 1 1 2 2 2 2 Golgin subfamily A member 7/ERF4 family CactinC_cactus PF09732.4 EGC36436.1 - 0.0071 15.9 1.6 0.016 14.8 1.1 1.6 1 0 0 1 1 1 1 Cactus-binding C-terminus of cactin protein DUF3278 PF11683.3 EGC36436.1 - 0.022 14.7 7.7 0.031 14.2 5.0 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3278) COX6B PF02297.12 EGC36436.1 - 0.49 10.4 3.1 1.2 9.2 0.2 2.3 2 0 0 2 2 2 0 Cytochrome oxidase c subunit VIb DUF4014 PF13198.1 EGC36436.1 - 6.5 7.2 10.6 28 5.1 7.4 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) PspB PF06667.7 EGC36437.1 - 0.56 10.1 4.6 17 5.4 0.1 2.8 2 0 0 2 2 2 0 Phage shock protein B DUF4446 PF14584.1 EGC36437.1 - 0.58 9.9 13.3 1.9 8.2 2.2 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Neur_chan_memb PF02932.11 EGC36437.1 - 0.83 9.4 7.7 1.6 8.5 5.3 1.6 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region p450 PF00067.17 EGC36439.1 - 3.6e-90 302.7 0.5 6e-90 301.9 0.3 1.3 1 1 0 1 1 1 1 Cytochrome P450 DNase_II PF03265.10 EGC36440.1 - 3.7e-26 91.9 9.7 1.4e-16 60.3 0.5 3.1 3 0 0 3 3 3 2 Deoxyribonuclease II Peptidase_S21 PF00716.12 EGC36441.1 - 0.075 12.3 2.4 0.085 12.1 1.6 1.1 1 0 0 1 1 1 0 Assemblin (Peptidase family S21) YcaO PF02624.11 EGC36441.1 - 0.21 11.0 0.7 0.36 10.2 0.5 1.4 1 0 0 1 1 1 0 YcaO-like family DUF3987 PF13148.1 EGC36441.1 - 0.51 8.8 8.8 0.7 8.4 6.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) DUF1682 PF07946.9 EGC36441.1 - 1.5 7.6 18.4 1.8 7.3 12.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1682) vATP-synt_E PF01991.13 EGC36441.1 - 3.3 6.9 25.1 0.37 10.0 1.6 2.5 1 1 1 2 2 2 0 ATP synthase (E/31 kDa) subunit GAGA_bind PF06217.7 EGC36441.1 - 4.3 7.2 11.0 5.1 6.9 7.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family DUF4557 PF15101.1 EGC36441.1 - 5.8 6.6 10.6 9.6 5.9 7.4 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) FNIP PF05725.7 EGC36442.1 - 2e-128 418.1 93.3 9.5e-16 57.4 0.8 12.6 8 3 3 13 13 13 12 FNIP Repeat DUF1769 PF08588.5 EGC36442.1 - 0.17 11.8 4.9 10 6.1 0.0 5.5 5 3 3 8 8 8 0 Protein of unknown function (DUF1769) TAP_C PF03943.8 EGC36442.1 - 0.24 10.8 2.1 1.4e+02 2.0 0.0 4.4 4 0 0 4 4 4 0 TAP C-terminal domain NosD PF05048.8 EGC36442.1 - 1.7 7.7 5.7 18 4.4 0.1 3.2 3 0 0 3 3 3 0 Periplasmic copper-binding protein (NosD) CLU PF13236.1 EGC36444.1 - 2.8e-54 183.9 0.0 6.5e-54 182.6 0.0 1.7 1 0 0 1 1 1 1 Clustered mitochondria eIF3_p135 PF12807.2 EGC36444.1 - 6.4e-10 39.2 3.2 1.2e-09 38.3 0.0 2.7 2 0 0 2 2 2 1 Translation initiation factor eIF3 subunit 135 DUF4270 PF14092.1 EGC36445.1 - 0.028 13.0 1.1 0.032 12.8 0.7 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4270) FNIP_M PF14637.1 EGC36446.1 - 0.018 14.6 0.0 0.028 13.9 0.0 1.3 1 0 0 1 1 1 0 Folliculin-interacting protein middle domain DUF4264 PF14084.1 EGC36447.1 - 0.014 14.7 0.0 0.051 12.9 0.0 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) DDE_3 PF13358.1 EGC36448.1 - 0.00072 19.3 0.1 0.001 18.8 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease Tir_receptor_C PF07489.6 EGC36449.1 - 2.5 7.8 10.9 6 6.5 7.5 1.6 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus HTH_29 PF13551.1 EGC36450.1 - 0.0008 19.5 0.1 0.0011 19.1 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_23 PF13384.1 EGC36450.1 - 0.0018 17.8 0.0 0.0033 17.0 0.0 1.4 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGC36450.1 - 0.013 15.4 0.1 0.019 14.9 0.0 1.3 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.14 EGC36450.1 - 0.037 13.7 0.0 0.048 13.3 0.0 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB PAX PF00292.13 EGC36450.1 - 0.079 12.6 0.0 0.1 12.3 0.0 1.2 1 0 0 1 1 1 0 'Paired box' domain ACP_syn_III_C PF08541.5 EGC36450.1 - 0.12 12.3 0.1 0.44 10.5 0.0 2.0 2 1 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal tRNA-synt_1b PF00579.20 EGC36450.1 - 0.12 11.4 0.0 0.14 11.2 0.0 1.2 1 0 0 1 1 1 0 tRNA synthetases class I (W and Y) Coatomer_WDAD PF04053.9 EGC36451.1 - 4.9e-11 42.0 5.9 0.021 13.6 0.0 4.4 4 1 0 4 4 4 4 Coatomer WD associated region WD40 PF00400.27 EGC36451.1 - 5.4e-06 26.0 0.0 0.18 11.7 0.0 4.3 4 0 0 4 4 4 2 WD domain, G-beta repeat Hira PF07569.6 EGC36451.1 - 0.047 12.9 0.0 0.047 12.9 0.0 2.9 3 0 0 3 3 3 0 TUP1-like enhancer of split AA_permease_2 PF13520.1 EGC36452.1 - 7.2e-33 113.7 57.1 9e-33 113.4 39.6 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC36452.1 - 4.6e-26 91.1 56.1 9.1e-26 90.2 38.9 1.4 1 1 0 1 1 1 1 Amino acid permease Adeno_E3_14_5 PF04834.7 EGC36452.1 - 0.029 14.7 0.3 0.029 14.7 0.2 3.4 2 2 1 3 3 3 0 Early E3 14.5 kDa protein ubiquitin PF00240.18 EGC36453.1 - 4.9e-150 487.1 34.6 2.2e-33 113.4 0.6 6.0 5 1 1 6 6 6 6 Ubiquitin family Rad60-SLD PF11976.3 EGC36453.1 - 7.5e-82 269.0 26.4 1.8e-18 65.9 0.4 6.0 5 1 1 6 6 6 6 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC36453.1 - 4.1e-26 91.0 13.1 0.00028 21.0 0.1 6.8 5 4 0 5 5 5 5 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGC36453.1 - 4.6e-19 68.6 3.6 0.0098 15.5 0.0 5.4 4 1 1 5 5 5 4 Telomere stability and silencing DUF2407 PF10302.4 EGC36453.1 - 1.6e-12 47.4 2.0 0.17 12.1 0.1 4.4 2 1 1 4 4 4 4 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGC36453.1 - 2.2e-12 46.8 4.3 0.28 11.0 0.0 5.3 5 2 0 5 5 5 4 Ubiquitin-2 like Rad60 SUMO-like DUF2870 PF11069.3 EGC36453.1 - 2.8e-10 40.1 0.0 1.9 8.5 0.0 4.9 4 0 0 4 4 4 4 Protein of unknown function (DUF2870) Big_3_3 PF13750.1 EGC36453.1 - 1.9e-07 30.6 0.2 16 4.9 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) TUG-UBL1 PF11470.3 EGC36453.1 - 1e-05 25.3 7.5 5.9 6.8 0.0 4.6 5 0 0 5 5 4 4 GLUT4 regulating protein TUG Corona_NS2A PF05213.7 EGC36453.1 - 3.8e-05 23.1 0.0 20 4.3 0.0 4.3 2 2 0 5 5 5 0 Coronavirus NS2A protein IGR PF09597.5 EGC36453.1 - 8.9e-05 22.3 0.1 43 4.1 0.0 4.4 4 0 0 4 4 4 0 IGR protein motif Plexin_cytopl PF08337.7 EGC36453.1 - 0.00029 19.3 14.9 2.5 6.3 0.1 6.7 5 3 1 7 7 7 4 Plexin cytoplasmic RasGAP domain Phage_pRha PF09669.5 EGC36453.1 - 0.00087 19.5 2.7 31 5.0 0.0 5.0 4 1 1 5 5 5 0 Phage regulatory protein Rha (Phage_pRha) DUF3435 PF11917.3 EGC36453.1 - 0.0016 17.2 0.5 28 3.2 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF3435) ACT_4 PF13291.1 EGC36453.1 - 0.0034 17.6 0.4 2e+02 2.3 0.0 4.9 5 0 0 5 5 5 0 ACT domain FlgD_ig PF13860.1 EGC36453.1 - 0.0068 16.1 8.6 48 3.7 0.0 5.1 5 0 0 5 5 5 0 FlgD Ig-like domain DUF3642 PF12182.3 EGC36453.1 - 0.0069 16.7 12.5 50 4.4 0.0 5.4 5 0 0 5 5 5 0 Bacterial lipoprotein Phage_GPD PF05954.6 EGC36453.1 - 0.039 13.1 2.0 0.61 9.2 0.1 3.0 1 1 2 3 3 3 0 Phage late control gene D protein (GPD) DUF3781 PF12636.2 EGC36453.1 - 0.061 13.2 8.1 77 3.3 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) Sortase PF04203.8 EGC36453.1 - 0.09 12.3 2.2 95 2.5 0.0 4.3 4 1 1 5 5 5 0 Sortase family GABP-alpha PF11620.3 EGC36453.1 - 0.13 12.2 6.3 69 3.5 0.1 4.2 4 1 0 4 4 4 0 GA-binding protein alpha chain Coiled PF05710.7 EGC36454.1 - 8.8e-07 29.3 16.1 8.8e-07 29.3 11.2 2.3 1 1 1 2 2 2 1 Coiled coil HIG_1_N PF04588.8 EGC36454.1 - 0.042 13.5 0.1 0.078 12.7 0.0 1.4 1 0 0 1 1 1 0 Hypoxia induced protein conserved region MIF PF01187.13 EGC36454.1 - 0.089 12.8 0.4 0.16 12.0 0.3 1.3 1 0 0 1 1 1 0 Macrophage migration inhibitory factor (MIF) UBX PF00789.15 EGC36455.1 - 5.4e-15 55.2 0.1 1.4e-14 53.9 0.0 1.7 1 0 0 1 1 1 1 UBX domain Thioredoxin_7 PF13899.1 EGC36455.1 - 0.00087 19.2 0.0 0.0026 17.7 0.0 1.7 2 0 0 2 2 2 1 Thioredoxin-like InvH PF04741.7 EGC36455.1 - 0.018 14.9 1.5 0.04 13.7 1.0 1.6 1 1 0 1 1 1 0 InvH outer membrane lipoprotein TIG PF01833.19 EGC36456.1 - 9.4e-65 214.6 104.3 6e-10 38.9 0.5 16.0 15 0 0 15 15 15 12 IPT/TIG domain LdpA_C PF12617.3 EGC36456.1 - 0.12 11.6 0.0 15 4.7 0.0 2.2 2 0 0 2 2 2 0 Iron-Sulfur binding protein C terminal TIG PF01833.19 EGC36457.1 - 5.5e-25 87.1 53.0 5.6e-10 39.0 1.8 6.7 7 0 0 7 7 7 4 IPT/TIG domain FNIP PF05725.7 EGC36458.1 - 2.9e-101 331.2 95.7 6.8e-13 48.3 0.9 10.7 6 1 7 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC36458.1 - 0.033 14.1 0.6 7.7 6.5 0.0 4.7 4 0 0 4 4 4 0 Protein of unknown function (DUF1769) Rapamycin_bind PF08771.6 EGC36458.1 - 0.11 12.6 0.0 0.92 9.6 0.0 2.3 2 0 0 2 2 2 0 Rapamycin binding domain Acetyltransf_1 PF00583.19 EGC36459.1 - 7.5e-14 51.5 0.0 9.1e-14 51.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_10 PF13673.1 EGC36459.1 - 3.5e-08 33.5 0.0 4.5e-08 33.2 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC36459.1 - 8.1e-07 29.1 0.0 1.1e-06 28.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC36459.1 - 2.2e-05 24.3 0.0 2.5e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC36459.1 - 2.4e-05 24.0 0.0 3.2e-05 23.5 0.0 1.2 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_CG PF14542.1 EGC36459.1 - 0.00029 20.6 0.0 0.0004 20.2 0.0 1.2 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase Acetyltransf_4 PF13420.1 EGC36459.1 - 0.00043 20.2 0.0 0.00048 20.1 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC36459.1 - 0.00045 20.0 0.0 0.00057 19.7 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC36459.1 - 0.0018 18.4 0.0 0.0025 18.0 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGC36459.1 - 0.016 14.7 0.0 0.02 14.5 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain TFIIE_beta PF02186.10 EGC36460.1 - 1.6e-06 27.9 0.2 4e-06 26.7 0.1 1.7 1 0 0 1 1 1 1 TFIIE beta subunit core domain DUF2250 PF10007.4 EGC36460.1 - 1.2 9.0 6.3 3 7.8 0.5 3.1 3 0 0 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2250) Acetyltransf_1 PF00583.19 EGC36461.1 - 4.5e-08 33.0 0.0 7.1e-08 32.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC36461.1 - 2.5e-07 30.7 0.0 3.9e-07 30.1 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC36461.1 - 1.3e-05 25.2 0.0 1.6e-05 24.8 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC36461.1 - 0.00015 21.8 0.0 0.0002 21.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC36461.1 - 0.009 16.1 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Glyco_hydro_cc PF11790.3 EGC36461.1 - 0.011 15.2 0.0 0.015 14.7 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase catalytic core Acetyltransf_CG PF14542.1 EGC36461.1 - 0.013 15.3 0.0 0.022 14.6 0.0 1.5 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase DUF3749 PF12568.3 EGC36461.1 - 0.016 14.8 0.1 0.021 14.4 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC36461.1 - 0.024 14.4 0.0 0.034 14.0 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC36461.1 - 0.053 13.3 0.0 0.078 12.8 0.0 1.3 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC36461.1 - 0.059 13.1 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 FR47-like protein FAT PF02259.18 EGC36462.1 - 1.4e-42 145.9 0.1 1.4e-42 145.9 0.1 2.3 2 0 0 2 2 2 1 FAT domain WW PF00397.21 EGC36463.1 - 1.5e-21 75.8 6.6 3.1e-10 39.7 0.7 2.4 2 0 0 2 2 2 2 WW domain DUF2781 PF10914.3 EGC36463.1 - 0.87 9.3 3.3 1.7 8.4 2.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2781) DUF605 PF04652.11 EGC36463.1 - 6.1 6.1 23.5 8.8 5.6 16.3 1.4 1 0 0 1 1 1 0 Vta1 like Aminotran_1_2 PF00155.16 EGC36464.1 - 9.1e-77 258.4 0.0 1.4e-76 257.8 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGC36464.1 - 3.2e-05 22.8 0.1 8.2e-05 21.4 0.0 1.7 2 1 0 2 2 2 1 Aminotransferase class-V Cys_Met_Meta_PP PF01053.15 EGC36464.1 - 0.0021 16.4 0.0 0.0035 15.6 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Not1 PF04054.10 EGC36464.1 - 0.086 11.6 0.0 0.14 10.9 0.0 1.3 1 0 0 1 1 1 0 CCR4-Not complex component, Not1 DUF1325 PF07039.6 EGC36465.1 - 8.3e-32 109.5 0.3 1.6e-31 108.5 0.2 1.5 1 0 0 1 1 1 1 SGF29 tudor-like domain Complex1_LYR PF05347.10 EGC36466.1 - 0.0051 16.5 0.1 0.0095 15.7 0.0 1.5 1 1 0 1 1 1 1 Complex 1 protein (LYR family) WD-3 PF09765.4 EGC36466.1 - 0.065 12.4 0.2 0.082 12.1 0.1 1.1 1 0 0 1 1 1 0 WD-repeat region Complex1_LYR_1 PF13232.1 EGC36466.1 - 0.074 13.2 1.1 0.22 11.7 0.8 2.0 1 1 0 1 1 1 0 Complex1_LYR-like Tub_2 PF04525.7 EGC36467.1 - 5.9e-17 61.6 2.3 7.7e-17 61.2 1.6 1.1 1 0 0 1 1 1 1 Tubby C 2 Tub_2 PF04525.7 EGC36468.1 - 3.7e-07 29.7 3.0 1.7e-06 27.5 2.0 1.8 1 1 0 1 1 1 1 Tubby C 2 Tub_2 PF04525.7 EGC36469.1 - 9.2e-08 31.6 0.3 1.1e-07 31.4 0.2 1.1 1 0 0 1 1 1 1 Tubby C 2 DUF3581 PF12119.3 EGC36469.1 - 0.11 11.6 0.0 0.14 11.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3581) DUF883 PF05957.8 EGC36470.1 - 1.3e-08 35.1 20.5 0.00018 21.8 2.6 4.6 1 1 5 6 6 6 6 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGC36470.1 - 2.4e-07 30.4 3.9 1.5e-06 27.8 2.7 2.0 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain YtxH PF12732.2 EGC36470.1 - 2.2e-05 24.7 39.3 0.34 11.3 4.9 5.2 1 1 2 3 3 3 1 YtxH-like protein Prominin PF05478.6 EGC36470.1 - 6.3e-05 20.7 14.7 7.5e-05 20.4 10.2 1.0 1 0 0 1 1 1 1 Prominin Tape_meas_lam_C PF09718.5 EGC36470.1 - 0.0019 18.0 30.2 0.096 12.6 2.3 5.1 1 1 3 5 5 5 2 Lambda phage tail tape-measure protein (Tape_meas_lam_C) DUF2580 PF10824.3 EGC36470.1 - 0.016 15.5 10.5 0.64 10.3 1.4 3.2 2 1 1 3 3 3 0 Protein of unknown function (DUF2580) DUF4175 PF13779.1 EGC36470.1 - 0.1 10.2 20.5 0.97 7.0 13.6 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_32 PF13654.1 EGC36470.1 - 0.11 11.1 13.8 0.76 8.3 2.5 2.1 1 1 1 2 2 2 0 AAA domain ApoC-I PF04691.7 EGC36470.1 - 0.13 12.0 15.4 0.23 11.1 0.1 3.7 2 1 2 4 4 4 0 Apolipoprotein C-I (ApoC-1) p450 PF00067.17 EGC36470.1 - 0.14 10.6 8.0 0.22 10.0 5.5 1.3 1 1 0 1 1 1 0 Cytochrome P450 WXG100 PF06013.7 EGC36470.1 - 0.15 12.0 18.2 0.5 10.4 3.0 4.0 1 1 3 4 4 4 0 Proteins of 100 residues with WXG OmpH PF03938.9 EGC36470.1 - 0.19 11.6 25.3 0.84 9.5 10.1 2.7 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) DUF3584 PF12128.3 EGC36470.1 - 0.19 9.0 21.9 0.69 7.1 15.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF3584) Clathrin_lg_ch PF01086.12 EGC36470.1 - 0.23 11.3 32.2 0.015 15.1 9.5 2.2 1 1 1 2 2 2 0 Clathrin light chain DUF2884 PF11101.3 EGC36470.1 - 0.25 10.7 21.3 0.46 9.8 6.7 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF2884) PhaP_Bmeg PF09602.5 EGC36470.1 - 0.25 11.1 19.9 1.5 8.6 6.3 2.7 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) DUF3708 PF12501.3 EGC36470.1 - 0.49 10.2 6.1 1.6 8.5 0.1 2.9 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter AAA_13 PF13166.1 EGC36470.1 - 0.58 8.5 28.3 0.58 8.5 17.2 1.6 1 1 0 1 1 1 0 AAA domain Mitofilin PF09731.4 EGC36470.1 - 0.85 8.2 27.5 1 7.9 19.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein ApoO PF09769.4 EGC36470.1 - 0.98 9.1 10.2 1.9 8.2 1.0 3.6 1 1 1 2 2 2 0 Apolipoprotein O DUF3106 PF11304.3 EGC36470.1 - 1.3 9.5 10.1 1.5 9.2 1.0 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3106) ApoLp-III PF07464.6 EGC36470.1 - 1.4 8.9 29.5 1 9.4 11.0 2.9 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) Baculo_PEP_C PF04513.7 EGC36470.1 - 2.1 8.1 10.1 1.9 8.3 0.6 3.1 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus Muted PF14942.1 EGC36470.1 - 3 7.6 17.1 0.1 12.4 3.8 2.3 1 1 1 2 2 2 0 Organelle biogenesis, Muted-like protein V-SNARE PF05008.10 EGC36470.1 - 3.8 7.7 8.3 5.3 7.2 3.0 3.1 1 1 1 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF2203 PF09969.4 EGC36470.1 - 5.8 7.1 11.8 5.7 7.1 2.4 3.1 1 1 2 3 3 3 0 Uncharacterized conserved protein (DUF2203) KMP11 PF03037.11 EGC36470.1 - 6.2 7.4 17.0 1.4 9.5 6.8 2.9 1 1 2 3 3 3 0 Kinetoplastid membrane protein 11 Band_7 PF01145.20 EGC36472.1 - 2.9e-30 105.5 2.0 3.5e-30 105.2 1.4 1.1 1 0 0 1 1 1 1 SPFH domain / Band 7 family UPF0158 PF03682.8 EGC36472.1 - 0.0094 15.5 1.0 0.011 15.3 0.3 1.6 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0158) MutS_II PF05188.12 EGC36472.1 - 0.032 14.2 0.2 0.056 13.5 0.1 1.4 1 1 0 1 1 1 0 MutS domain II U3_assoc_6 PF08640.6 EGC36472.1 - 0.39 10.4 3.7 1.5 8.6 0.3 2.8 2 1 1 3 3 3 0 U3 small nucleolar RNA-associated protein 6 Cation_efflux PF01545.16 EGC36473.1 - 6.9e-43 146.7 4.2 9.4e-43 146.3 2.9 1.1 1 0 0 1 1 1 1 Cation efflux family WASH-7_N PF14745.1 EGC36473.1 - 0.043 12.0 0.2 0.058 11.5 0.1 1.1 1 0 0 1 1 1 0 WASH complex subunit 7, N-terminal Methyltransf_11 PF08241.7 EGC36474.1 - 4.2e-16 59.2 0.0 2.8e-15 56.5 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36474.1 - 8.8e-11 41.7 0.0 1.4e-10 41.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC36474.1 - 1.9e-10 40.5 0.0 4.3e-10 39.3 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36474.1 - 2.9e-10 40.7 0.0 5.1e-10 39.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36474.1 - 4e-09 36.8 0.0 2.4e-08 34.3 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC36474.1 - 1.3e-07 31.0 0.0 2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGC36474.1 - 4e-06 27.1 0.0 1.1e-05 25.7 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC36474.1 - 0.00043 20.2 0.0 0.00082 19.3 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain RrnaAD PF00398.15 EGC36474.1 - 0.00049 19.2 0.0 0.00077 18.5 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_PK PF05891.7 EGC36474.1 - 0.00091 18.5 0.0 0.0015 17.8 0.0 1.4 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_8 PF05148.10 EGC36474.1 - 0.0013 18.4 0.0 0.015 14.9 0.0 2.1 1 1 0 1 1 1 1 Hypothetical methyltransferase FtsJ PF01728.14 EGC36474.1 - 0.0053 16.7 0.0 0.028 14.4 0.0 2.0 1 1 0 1 1 1 1 FtsJ-like methyltransferase DUF938 PF06080.7 EGC36474.1 - 0.0076 15.8 0.0 0.013 15.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) PCMT PF01135.14 EGC36474.1 - 0.0086 15.6 0.0 0.027 13.9 0.0 1.8 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) MTS PF05175.9 EGC36474.1 - 0.079 12.3 0.0 0.18 11.1 0.0 1.6 1 1 0 1 1 1 0 Methyltransferase small domain MetW PF07021.7 EGC36474.1 - 0.1 11.9 0.0 0.27 10.5 0.0 1.8 1 1 0 1 1 1 0 Methionine biosynthesis protein MetW zf-TRAF PF02176.13 EGC36475.1 - 2.9e-10 40.3 38.8 2.8e-08 33.9 7.8 5.1 2 2 3 5 5 5 4 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC36475.1 - 0.00032 20.6 11.1 0.00032 20.6 7.7 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC36475.1 - 0.0012 18.4 12.3 0.0012 18.4 8.5 3.1 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC36475.1 - 0.0043 16.7 2.4 0.0043 16.7 1.7 3.2 2 1 2 4 4 4 1 Seven in absentia protein family zf-U11-48K PF05253.7 EGC36475.1 - 0.0093 15.6 2.1 11 5.8 0.1 4.1 3 0 0 3 3 3 1 U11-48K-like CHHC zinc finger TMF_DNA_bd PF12329.3 EGC36475.1 - 0.037 13.8 5.6 0.11 12.3 3.9 1.7 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding SLIDE PF09111.5 EGC36475.1 - 0.58 9.8 5.0 0.68 9.6 1.3 2.5 2 0 0 2 2 2 0 SLIDE ParA PF10609.4 EGC36476.1 - 4.9e-34 116.0 0.5 1.2e-33 114.8 0.3 1.6 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGC36476.1 - 1.5e-07 31.0 0.0 2.3e-07 30.3 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_26 PF13500.1 EGC36476.1 - 0.0079 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA domain Rad50_zn_hook PF04423.9 EGC36476.1 - 0.22 11.0 4.9 3.7 7.0 0.9 2.6 2 0 0 2 2 2 0 Rad50 zinc hook motif Acetyltransf_2 PF00797.12 EGC36477.1 - 3.1e-09 36.7 0.1 1.5e-08 34.5 0.1 1.8 1 1 0 1 1 1 1 N-acetyltransferase EDR1 PF14381.1 EGC36477.1 - 0.028 13.9 0.0 0.045 13.3 0.0 1.3 1 0 0 1 1 1 0 Ethylene-responsive protein kinase Le-CTR1 BRCT PF00533.21 EGC36478.1 - 5e-13 49.0 0.8 2.5e-05 24.3 0.1 3.2 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain NAD_binding_10 PF13460.1 EGC36479.1 - 3.1e-18 66.4 0.0 4.4e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC36479.1 - 3.7e-13 49.0 0.0 2.5e-11 43.0 0.0 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGC36479.1 - 6.8e-11 42.0 0.0 5e-10 39.2 0.0 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGC36479.1 - 1.9e-10 40.3 0.0 3e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family 3Beta_HSD PF01073.14 EGC36479.1 - 5.4e-10 38.4 0.0 5.2e-08 31.9 0.0 2.1 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGC36479.1 - 2.8e-09 36.2 1.0 0.0034 16.3 0.5 3.1 1 1 1 2 2 2 2 Male sterility protein Saccharop_dh PF03435.13 EGC36479.1 - 0.00022 20.3 0.0 0.00033 19.7 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase adh_short PF00106.20 EGC36479.1 - 0.086 12.7 0.0 0.14 12.1 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase His_Phos_2 PF00328.17 EGC36480.1 - 1.3e-25 90.5 0.0 1.9e-25 89.9 0.0 1.3 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) Asn_synthase PF00733.16 EGC36481.1 - 6e-71 238.9 0.0 8.2e-71 238.4 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC36481.1 - 7.6e-43 145.2 0.0 1.3e-42 144.5 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC36481.1 - 1.2e-33 115.8 0.0 2.3e-33 114.9 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain DUF3700 PF12481.3 EGC36481.1 - 7.7e-17 61.2 0.0 1.3e-16 60.4 0.0 1.3 1 0 0 1 1 1 1 Aluminium induced protein GATase_2 PF00310.16 EGC36481.1 - 3.2e-09 35.9 0.0 0.051 12.2 0.0 3.2 1 1 2 3 3 3 3 Glutamine amidotransferases class-II tRNA_Me_trans PF03054.11 EGC36481.1 - 0.023 13.2 0.0 0.038 12.5 0.0 1.2 1 0 0 1 1 1 0 tRNA methyl transferase NAD_synthase PF02540.12 EGC36481.1 - 0.036 12.9 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 NAD synthase DUF1933 PF09147.5 EGC36481.1 - 0.088 12.2 0.0 0.15 11.4 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1933) Cellulase PF00150.13 EGC36482.1 - 9e-29 100.5 0.7 1.8e-28 99.5 0.5 1.4 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Peptidase_C9 PF01707.11 EGC36482.1 - 0.023 14.3 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 Peptidase family C9 PMT_2 PF13231.1 EGC36483.1 - 0.016 15.0 5.3 0.016 15.0 3.7 2.7 3 0 0 3 3 3 0 Dolichyl-phosphate-mannose-protein mannosyltransferase DUF912 PF06024.7 EGC36483.1 - 0.093 12.7 0.0 0.093 12.7 0.0 3.4 2 1 1 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF4064 PF13273.1 EGC36483.1 - 2 8.5 12.2 5.2 7.2 0.7 3.6 1 1 2 3 3 3 0 Protein of unknown function (DUF4064) NUDIX PF00293.23 EGC36485.1 - 1.5e-14 53.7 0.0 2.4e-14 53.1 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain zf-C3HC PF07967.8 EGC36485.1 - 0.028 14.2 0.0 0.085 12.6 0.0 1.8 1 0 0 1 1 1 0 C3HC zinc finger-like Viral_Beta_CD PF04530.7 EGC36485.1 - 6.2 7.0 7.2 2.6 8.2 2.3 2.2 2 0 0 2 2 2 0 Viral Beta C/D like family Acyl-CoA_dh_1 PF00441.19 EGC36486.1 - 5.7e-28 97.9 0.1 1e-27 97.0 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGC36486.1 - 2.7e-26 92.3 0.0 6.7e-26 91.0 0.0 1.7 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_M PF02770.14 EGC36486.1 - 4e-20 71.0 0.6 8.7e-20 69.9 0.1 1.9 2 0 0 2 2 2 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGC36486.1 - 1e-07 32.2 0.0 1.5e-07 31.6 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain ABC_tran PF00005.22 EGC36488.1 - 1.2e-23 83.8 0.1 5.8e-15 55.7 0.0 2.9 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EGC36488.1 - 0.0081 15.6 0.4 0.11 12.0 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain Semialdhyde_dh PF01118.19 EGC36489.1 - 8.4e-25 87.4 0.0 1.9e-24 86.2 0.0 1.6 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain AA_kinase PF00696.23 EGC36489.1 - 2.6e-19 69.7 0.4 1.3e-18 67.4 0.0 2.2 2 0 0 2 2 2 1 Amino acid kinase family DUF619 PF04768.8 EGC36489.1 - 3.6e-13 49.2 6.7 7.6e-13 48.2 4.7 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF619) DapB_N PF01113.15 EGC36489.1 - 0.016 15.1 0.0 0.053 13.4 0.0 2.0 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus DUF1803 PF08820.5 EGC36489.1 - 0.017 14.7 0.2 0.046 13.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF1803) 7tm_2 PF00002.19 EGC36490.1 - 1.9e-22 79.5 18.5 2.4e-22 79.2 12.8 1.1 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Dicty_CAR PF05462.6 EGC36490.1 - 4.4e-20 71.7 23.9 5.5e-20 71.4 16.6 1.1 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor Ocular_alb PF02101.10 EGC36490.1 - 1.9e-10 39.9 3.1 2.6e-10 39.4 2.2 1.2 1 0 0 1 1 1 1 Ocular albinism type 1 protein Frizzled PF01534.12 EGC36490.1 - 8e-06 24.8 5.6 8e-06 24.8 3.8 2.2 1 1 1 2 2 2 1 Frizzled/Smoothened family membrane region Tim17 PF02466.14 EGC36491.1 - 0.001 19.0 3.7 0.0015 18.5 2.6 1.1 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family Bacteriocin_IIc PF10439.4 EGC36491.1 - 5.6 7.1 8.3 4.1 7.6 0.5 2.2 2 0 0 2 2 2 0 Bacteriocin class II with double-glycine leader peptide Elf1 PF05129.8 EGC36492.1 - 5.5e-30 102.8 1.3 6.3e-30 102.7 0.9 1.0 1 0 0 1 1 1 1 Transcription elongation factor Elf1 like Rubredoxin PF00301.15 EGC36492.1 - 0.00085 19.1 1.8 0.028 14.2 0.2 2.3 2 0 0 2 2 2 1 Rubredoxin Lar_restr_allev PF14354.1 EGC36492.1 - 0.036 14.3 2.4 0.044 14.0 1.6 1.2 1 0 0 1 1 1 0 Restriction alleviation protein Lar zf-CHY PF05495.7 EGC36492.1 - 0.064 13.4 1.1 0.089 12.9 0.7 1.2 1 0 0 1 1 1 0 CHY zinc finger Cys_rich_CPXG PF14255.1 EGC36492.1 - 0.073 12.9 4.9 0.054 13.3 2.6 1.5 1 1 0 1 1 1 0 Cysteine-rich CPXCG Zn_Tnp_IS1595 PF12760.2 EGC36492.1 - 0.24 11.2 1.9 0.43 10.4 1.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain zf-Sec23_Sec24 PF04810.10 EGC36492.1 - 0.25 10.9 2.4 0.97 9.0 0.1 2.2 1 1 1 2 2 2 0 Sec23/Sec24 zinc finger zf-H2C2_2 PF13465.1 EGC36492.1 - 1.2 9.5 4.6 6.8 7.1 0.6 2.3 2 0 0 2 2 2 0 Zinc-finger double domain Prim_Zn_Ribbon PF08273.7 EGC36492.1 - 2.5 8.2 6.7 10 6.2 4.6 1.9 1 1 0 1 1 1 0 Zinc-binding domain of primase-helicase Zn_Tnp_IS1 PF03811.8 EGC36492.1 - 5.9 6.4 6.4 28 4.3 4.5 2.1 1 1 0 1 1 1 0 InsA N-terminal domain Ank_2 PF12796.2 EGC36493.1 - 0.00017 21.8 1.8 0.27 11.6 0.0 3.7 3 2 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC36493.1 - 0.0032 17.9 0.3 17 6.0 0.0 4.8 3 1 2 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36493.1 - 0.32 11.3 7.7 27 5.4 0.0 5.9 8 0 0 8 8 8 0 Ankyrin repeat Ank_2 PF12796.2 EGC36494.1 - 5.5e-05 23.4 0.0 0.015 15.5 0.0 3.2 2 2 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC36494.1 - 0.42 11.0 5.9 5.3 7.5 0.0 5.7 7 0 0 7 7 7 0 Ankyrin repeat TPR_11 PF13414.1 EGC36495.1 - 2.9e-23 81.2 18.8 5.6e-09 35.5 1.1 5.3 4 2 3 7 7 6 5 TPR repeat TPR_2 PF07719.12 EGC36495.1 - 1.6e-17 61.9 2.7 0.00072 19.2 0.0 6.2 6 0 0 6 6 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGC36495.1 - 2.1e-17 61.8 4.0 0.00055 19.4 0.2 5.1 4 0 0 4 4 4 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGC36495.1 - 1.6e-16 59.0 14.0 0.00043 20.2 0.2 6.1 6 0 0 6 6 6 4 Tetratricopeptide repeat TPR_14 PF13428.1 EGC36495.1 - 1.1e-14 53.6 0.1 0.0075 16.8 0.0 6.4 2 2 4 6 6 6 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC36495.1 - 1.8e-14 53.9 1.3 3.4e-06 27.5 0.1 4.6 3 2 2 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC36495.1 - 2.1e-13 50.4 2.3 0.032 14.5 0.0 4.6 2 2 3 5 5 5 5 Tetratricopeptide repeat TPR_20 PF14561.1 EGC36495.1 - 6.7e-11 42.1 1.3 0.024 14.7 0.0 4.8 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC36495.1 - 5e-09 35.9 9.2 0.029 14.3 0.2 4.4 3 1 1 4 4 4 3 Tetratricopeptide repeat TPR_9 PF13371.1 EGC36495.1 - 1.3e-06 28.1 0.6 0.027 14.3 0.0 4.3 4 1 1 5 5 5 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC36495.1 - 8.7e-06 25.1 4.4 1.4 8.8 0.0 5.3 6 0 0 6 6 5 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC36495.1 - 2.2e-05 24.5 2.8 0.13 12.4 0.5 2.4 2 0 0 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_8 PF13181.1 EGC36495.1 - 4e-05 23.0 4.5 1.2 9.0 0.2 5.1 4 1 1 5 5 5 1 Tetratricopeptide repeat ChAPs PF09295.5 EGC36495.1 - 0.0026 16.5 2.8 0.17 10.6 0.0 2.9 4 0 0 4 4 4 1 ChAPs (Chs5p-Arf1p-binding proteins) TPR_6 PF13174.1 EGC36495.1 - 0.0099 16.2 1.4 14 6.4 0.0 4.7 5 0 0 5 5 4 0 Tetratricopeptide repeat DUF4248 PF14053.1 EGC36495.1 - 0.027 14.0 1.2 0.058 12.9 0.1 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4248) PPTA PF01239.17 EGC36495.1 - 0.053 12.8 2.2 21 4.6 0.1 3.8 3 0 0 3 3 3 0 Protein prenyltransferase alpha subunit repeat DUF3439 PF11921.3 EGC36496.1 - 0.16 11.7 7.4 1.1 9.0 0.3 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Histone_HNS PF00816.16 EGC36497.1 - 0.054 14.0 1.0 0.12 12.8 0.1 1.8 2 0 0 2 2 2 0 H-NS histone family DUF2315 PF10231.4 EGC36497.1 - 0.062 13.1 0.3 0.12 12.2 0.0 1.7 2 1 0 2 2 2 0 Uncharacterised conserved protein (DUF2315) Gamma-thionin PF00304.15 EGC36497.1 - 0.91 9.5 5.9 3.5 7.7 2.3 2.3 2 0 0 2 2 2 0 Gamma-thionin family EGF_2 PF07974.8 EGC36498.1 - 5.2e-05 23.3 29.4 0.00087 19.4 7.5 3.2 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.5 EGC36498.1 - 0.046 13.0 4.1 0.087 12.1 1.5 2.4 2 0 0 2 2 2 0 Transmembrane alpha-helix domain Spheroidin PF05541.7 EGC36499.1 - 3.4e-05 21.7 7.7 4.2e-05 21.3 5.3 1.1 1 0 0 1 1 1 1 Entomopoxvirus spheroidin protein Peptidase_M16 PF00675.15 EGC36500.1 - 1.3e-21 76.9 0.0 2.7e-21 75.9 0.0 1.5 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Peptidase_M16_C PF05193.16 EGC36500.1 - 8.2e-13 48.4 0.0 2.2e-12 47.0 0.0 1.7 1 0 0 1 1 1 1 Peptidase M16 inactive domain TPK_B1_binding PF04265.9 EGC36500.1 - 0.74 9.5 6.0 1.6 8.5 0.0 3.3 3 0 0 3 3 3 0 Thiamin pyrophosphokinase, vitamin B1 binding domain Pho88 PF10032.4 EGC36501.1 - 0.018 14.2 0.3 0.018 14.2 0.2 1.9 2 0 0 2 2 2 0 Phosphate transport (Pho88) DUF1336 PF07059.7 EGC36501.1 - 0.028 13.8 3.2 0.041 13.2 2.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1336) Herpes_LAMP2 PF06126.6 EGC36502.1 - 0.044 12.2 0.1 0.049 12.0 0.1 1.0 1 0 0 1 1 1 0 Herpesvirus Latent membrane protein 2 Toxin_13 PF07822.6 EGC36502.1 - 0.2 11.5 1.7 0.23 11.3 0.3 1.7 1 1 0 1 1 1 0 Neurotoxin B-IV-like protein NDUF_C2 PF06374.6 EGC36504.1 - 0.062 13.3 0.0 0.071 13.1 0.0 1.2 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit b14.5b (NDUFC2) Evr1_Alr PF04777.8 EGC36505.1 - 1.3e-30 105.0 0.1 3.1e-30 103.9 0.1 1.6 1 0 0 1 1 1 1 Erv1 / Alr family Bac_surface_Ag PF01103.18 EGC36506.1 - 6.4e-11 42.2 14.4 8.9e-11 41.8 10.0 1.2 1 0 0 1 1 1 1 Surface antigen Helicase_RecD PF05127.9 EGC36506.1 - 0.059 12.9 0.0 0.1 12.1 0.0 1.3 1 0 0 1 1 1 0 Helicase Phospholip_B PF04916.8 EGC36508.1 - 1.2e-130 436.2 7.6 1.4e-130 436.0 5.3 1.0 1 0 0 1 1 1 1 Phospholipase B Ependymin PF00811.13 EGC36509.1 - 0.0098 15.6 0.6 0.02 14.5 0.4 1.5 1 0 0 1 1 1 1 Ependymin Claudin_3 PF06653.6 EGC36509.1 - 0.11 12.2 0.8 0.24 11.0 0.1 1.8 2 0 0 2 2 2 0 Tight junction protein, Claudin-like FNIP PF05725.7 EGC36510.1 - 6e-23 80.5 71.7 1.2e-09 37.9 0.1 12.3 9 3 4 13 13 13 10 FNIP Repeat C2 PF00168.25 EGC36511.1 - 1.5e-08 34.3 2.5 3.4e-08 33.2 1.7 1.9 1 1 0 1 1 1 1 C2 domain DUF1071 PF06378.6 EGC36511.1 - 0.065 12.3 0.2 0.11 11.6 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1071) Endotoxin_N PF03945.9 EGC36512.1 - 8.6e-12 44.9 2.6 3e-11 43.1 0.2 2.7 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain p450 PF00067.17 EGC36514.1 - 5.4e-88 295.5 2.3 6.1e-88 295.3 1.6 1.0 1 0 0 1 1 1 1 Cytochrome P450 FixP_N PF14715.1 EGC36514.1 - 0.11 11.9 0.1 0.31 10.4 0.0 1.8 1 0 0 1 1 1 0 N-terminal domain of cytochrome oxidase-cbb3, FixP Fimbrillin_C PF15495.1 EGC36515.1 - 0.15 12.2 1.5 0.62 10.2 0.1 2.2 2 0 0 2 2 2 0 Major fimbrial subunit protein type IV, Fimbrillin, C-terminal FNIP PF05725.7 EGC36516.1 - 9.7e-69 227.0 82.5 8.3e-10 38.4 0.4 13.1 2 2 14 17 17 17 17 FNIP Repeat zf-TRAF PF02176.13 EGC36517.1 - 2.5e-13 50.1 30.8 3e-11 43.5 6.2 4.6 3 2 1 4 4 4 2 TRAF-type zinc finger zf-RING_2 PF13639.1 EGC36517.1 - 6.4e-08 32.3 9.2 6.4e-08 32.3 6.4 2.8 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC36517.1 - 6.9e-07 29.1 11.0 6.9e-07 29.1 7.6 2.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC36517.1 - 3.4e-06 26.6 6.6 3.4e-06 26.6 4.6 2.9 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC36517.1 - 9.8e-06 25.3 8.2 9.8e-06 25.3 5.7 3.0 2 1 1 3 3 3 1 zinc finger of C3HC4-type, RING MATH PF00917.21 EGC36517.1 - 0.00018 21.7 0.3 0.00018 21.7 0.2 2.9 3 1 0 4 4 4 1 MATH domain zf-C3HC4 PF00097.20 EGC36517.1 - 0.00037 20.1 10.8 0.00037 20.1 7.5 3.0 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) DUF1272 PF06906.6 EGC36517.1 - 0.009 15.8 4.4 0.009 15.8 3.1 3.6 2 1 1 3 3 3 1 Protein of unknown function (DUF1272) zf-rbx1 PF12678.2 EGC36517.1 - 0.017 15.2 5.3 0.017 15.2 3.7 3.2 2 1 0 2 2 2 0 RING-H2 zinc finger Sina PF03145.11 EGC36517.1 - 0.21 11.2 24.0 4.7 6.8 0.0 4.3 3 1 1 4 4 4 0 Seven in absentia protein family zf-Di19 PF05605.7 EGC36517.1 - 0.33 11.0 12.6 5.5 7.1 0.0 3.9 4 0 0 4 4 4 0 Drought induced 19 protein (Di19), zinc-binding tRNA-synt_2 PF00152.15 EGC36518.1 - 3.2e-78 262.8 1.1 4.1e-78 262.4 0.8 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGC36518.1 - 1.1e-05 25.2 0.2 2.6e-05 24.0 0.1 1.7 1 0 0 1 1 1 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGC36518.1 - 0.0047 16.1 0.6 0.63 9.1 0.0 2.3 2 0 0 2 2 2 2 tRNA synthetases class II core domain (F) 4HB_MCP_1 PF12729.2 EGC36518.1 - 0.0067 15.8 0.3 0.013 14.8 0.2 1.4 1 0 0 1 1 1 1 Four helix bundle sensory module for signal transduction Pex2_Pex12 PF04757.9 EGC36519.1 - 6.6e-45 153.3 7.8 1.3e-44 152.3 5.4 1.5 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4 PF00097.20 EGC36519.1 - 2.5e-06 27.0 12.9 4.6e-06 26.1 8.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36519.1 - 5.5e-06 26.3 14.0 9.1e-06 25.6 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC36519.1 - 2.3e-05 23.9 9.1 3.5e-05 23.3 6.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC36519.1 - 2.7e-05 23.8 11.5 4.3e-05 23.2 8.0 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC36519.1 - 5.8e-05 22.7 11.5 9.1e-05 22.1 7.9 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC36519.1 - 0.00019 21.2 15.2 0.00032 20.4 10.5 1.4 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC36519.1 - 0.046 13.4 7.2 0.13 11.9 5.0 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-rbx1 PF12678.2 EGC36519.1 - 0.24 11.5 5.1 0.51 10.4 3.5 1.5 1 0 0 1 1 1 0 RING-H2 zinc finger DUF3446 PF11928.3 EGC36519.1 - 0.96 9.6 13.4 0.41 10.8 1.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3446) FNIP PF05725.7 EGC36520.1 - 1.3e-06 28.1 25.3 0.13 12.2 0.4 6.4 4 2 2 6 6 6 4 FNIP Repeat SOG2 PF10428.4 EGC36520.1 - 0.037 12.7 0.0 0.049 12.2 0.0 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein Secretin_N_2 PF07655.8 EGC36520.1 - 5 7.5 22.2 12 6.3 15.4 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.7 EGC36521.1 - 2.5e-66 219.4 65.6 1.7e-13 50.2 0.1 11.5 7 3 3 12 12 12 9 FNIP Repeat FNIP PF05725.7 EGC36522.1 - 3.3e-102 334.2 83.9 1.3e-14 53.8 0.6 14.8 2 1 13 17 17 17 16 FNIP Repeat DUF1769 PF08588.5 EGC36522.1 - 1.2e-07 31.5 8.4 0.32 10.9 0.0 7.6 5 2 3 8 8 8 4 Protein of unknown function (DUF1769) Barstar PF01337.13 EGC36523.1 - 3.9e-05 23.3 0.2 9.6e-05 22.1 0.1 1.6 1 1 1 2 2 2 1 Barstar (barnase inhibitor) KRAB PF01352.22 EGC36523.1 - 0.064 12.7 0.0 0.13 11.7 0.0 1.5 1 0 0 1 1 1 0 KRAB box AMP_N PF05195.11 EGC36523.1 - 0.074 12.4 0.0 0.1 12.0 0.0 1.1 1 0 0 1 1 1 0 Aminopeptidase P, N-terminal domain Asp_protease_2 PF13650.1 EGC36524.1 - 0.001 19.5 0.0 0.0042 17.5 0.0 2.0 2 0 0 2 2 2 1 Aspartyl protease gag-asp_proteas PF13975.1 EGC36524.1 - 0.0013 18.4 0.0 0.0024 17.6 0.0 1.4 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGC36524.1 - 0.0077 16.1 0.0 0.031 14.2 0.0 2.0 2 0 0 2 2 2 1 Retroviral aspartyl protease DUF1411 PF07199.6 EGC36524.1 - 0.064 12.6 0.1 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1411) Lant_dehyd_C PF04738.8 EGC36524.1 - 0.08 11.1 0.0 0.11 10.6 0.0 1.2 1 0 0 1 1 1 0 Lantibiotic dehydratase, C terminus FNIP PF05725.7 EGC36525.1 - 7.5e-30 102.6 33.7 1.9e-11 43.7 0.2 4.8 1 1 5 7 7 7 6 FNIP Repeat DUF538 PF04398.7 EGC36525.1 - 0.032 14.4 0.9 33 4.7 0.0 3.1 2 1 1 3 3 3 0 Protein of unknown function, DUF538 Chordopox_A20R PF05941.8 EGC36526.1 - 0.0095 14.7 0.1 0.014 14.1 0.1 1.3 1 1 0 1 1 1 1 Chordopoxvirus A20R protein DUF3430 PF11912.3 EGC36527.1 - 4e-40 137.9 38.3 5.3e-40 137.5 26.4 1.3 1 1 0 1 1 1 1 Protein of unknown function (DUF3430) COesterase PF00135.23 EGC36528.1 - 2.9e-123 412.4 0.0 3.5e-123 412.1 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC36528.1 - 0.00016 21.3 0.2 0.00066 19.3 0.1 1.9 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC36528.1 - 0.0039 16.4 0.2 0.006 15.8 0.2 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC36528.1 - 0.06 13.1 0.0 0.088 12.5 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Endotoxin_N PF03945.9 EGC36529.1 - 2.3e-14 53.3 1.7 8.2e-14 51.5 0.0 2.5 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain COesterase PF00135.23 EGC36530.1 - 4.5e-121 405.1 0.0 5.7e-121 404.8 0.0 1.1 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC36530.1 - 9.9e-06 25.2 0.0 2.7e-05 23.8 0.0 1.7 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC36530.1 - 0.0039 16.4 0.0 0.0059 15.8 0.0 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC36530.1 - 0.047 13.4 0.0 0.067 12.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family KR PF08659.5 EGC36531.1 - 3.8e-11 42.9 0.0 4.5e-11 42.7 0.0 1.1 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC36531.1 - 1.8e-05 24.7 0.0 2.2e-05 24.4 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase TypeIII_RM_meth PF12564.3 EGC36531.1 - 1.6 8.7 13.5 11 6.0 0.0 3.3 2 1 1 3 3 3 0 Type III restriction/modification enzyme methylation subunit Methyltransf_31 PF13847.1 EGC36532.1 - 0.038 13.5 4.9 0.037 13.6 2.4 1.9 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36532.1 - 0.072 12.8 0.0 0.12 12.0 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain DUF4264 PF14084.1 EGC36533.1 - 0.02 14.2 0.0 0.025 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4264) RNase_T PF00929.19 EGC36534.1 - 8.4e-06 26.1 0.3 6e-05 23.3 0.1 2.4 1 1 0 2 2 2 1 Exonuclease RNase_H_2 PF13482.1 EGC36534.1 - 0.018 14.8 0.3 0.041 13.6 0.2 1.8 1 1 0 1 1 1 0 RNase_H superfamily Pox_Ag35 PF03286.9 EGC36537.1 - 0.23 10.9 3.0 0.28 10.6 2.1 1.0 1 0 0 1 1 1 0 Pox virus Ag35 surface protein GATA PF00320.22 EGC36539.1 - 1.3e-07 30.8 2.5 1.3e-07 30.8 1.7 2.2 2 1 0 2 2 2 1 GATA zinc finger Zn-ribbon_8 PF09723.5 EGC36539.1 - 0.14 12.1 1.5 0.3 11.0 0.1 2.1 2 0 0 2 2 2 0 Zinc ribbon domain zf-RING_3 PF14369.1 EGC36539.1 - 9.7 6.2 6.8 0.28 11.1 0.4 1.6 2 0 0 2 2 2 0 zinc-finger Homeobox PF00046.24 EGC36542.1 - 9.4e-13 47.5 0.8 6.6e-07 28.8 0.0 2.5 2 0 0 2 2 2 2 Homeobox domain Homeobox_KN PF05920.6 EGC36542.1 - 0.00034 20.2 0.5 0.48 10.1 0.0 2.7 2 0 0 2 2 2 2 Homeobox KN domain DUF1675 PF07897.6 EGC36542.1 - 0.59 9.9 6.2 0.9 9.3 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1675) GRAM PF02893.15 EGC36543.1 - 0.082 12.4 0.1 0.18 11.3 0.1 1.6 1 0 0 1 1 1 0 GRAM domain GATA PF00320.22 EGC36544.1 - 3.7e-08 32.5 6.9 1.1e-07 31.1 4.8 1.8 1 1 0 1 1 1 1 GATA zinc finger DUF4508 PF14969.1 EGC36544.1 - 0.046 13.7 0.2 0.056 13.4 0.1 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4508) AT_hook PF02178.14 EGC36544.1 - 0.054 13.1 7.4 0.11 12.2 5.1 1.6 1 0 0 1 1 1 0 AT hook motif F-box PF00646.28 EGC36546.1 - 0.00017 21.1 0.1 0.00026 20.5 0.1 1.4 1 1 0 1 1 1 1 F-box domain F-box-like PF12937.2 EGC36546.1 - 0.037 13.7 0.0 0.052 13.2 0.0 1.4 1 1 0 1 1 1 0 F-box-like DDE_Tnp_1_7 PF13843.1 EGC36548.1 - 3.6e-14 52.5 1.7 5.1e-14 52.0 1.2 1.1 1 0 0 1 1 1 1 Transposase IS4 PPV_E2_N PF00508.12 EGC36549.1 - 0.064 12.4 0.4 0.11 11.6 0.3 1.3 1 1 0 1 1 1 0 E2 (early) protein, N terminal GATA PF00320.22 EGC36550.1 - 9.8e-08 31.2 4.3 1.9e-07 30.3 3.0 1.5 1 0 0 1 1 1 1 GATA zinc finger Gln-synt_N PF03951.14 EGC36551.1 - 0.073 12.6 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Glutamine synthetase, beta-Grasp domain UPF0137 PF03677.8 EGC36551.1 - 0.1 12.1 2.9 1.9 7.9 2.4 1.9 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0137) Ribophorin_II PF05817.9 EGC36552.1 - 1.7e-73 247.9 15.2 2.2e-73 247.5 10.5 1.0 1 0 0 1 1 1 1 Oligosaccharyltransferase subunit Ribophorin II Prenyltrans_2 PF13249.1 EGC36552.1 - 0.0021 18.4 1.6 0.34 11.3 0.2 3.0 1 1 1 2 2 2 2 Prenyltransferase-like Pkinase PF00069.20 EGC36553.1 - 9.7e-46 156.0 0.3 2e-45 154.9 0.2 1.4 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36553.1 - 1.2e-44 152.3 0.1 2e-44 151.6 0.1 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase bcl-2I13 PF12201.3 EGC36553.1 - 0.11 11.9 0.0 0.19 11.2 0.0 1.3 1 0 0 1 1 1 0 Bcl2-interacting killer, BH3-domain containing RNase_T PF00929.19 EGC36555.1 - 1.8e-05 25.0 0.0 0.00063 20.0 0.0 2.5 1 1 1 2 2 2 1 Exonuclease FNIP PF05725.7 EGC36556.1 - 5.3e-31 106.3 34.9 2.9e-10 39.9 1.6 9.6 5 3 5 10 10 10 9 FNIP Repeat DUF1077 PF06417.7 EGC36559.1 - 0.072 12.4 0.2 0.1 11.9 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1077) FNIP PF05725.7 EGC36560.1 - 1.2e-40 137.1 44.6 4.2e-12 45.8 0.6 9.4 6 2 5 11 11 11 8 FNIP Repeat DNA_methylase PF00145.12 EGC36561.1 - 0.00021 20.5 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 C-5 cytosine-specific DNA methylase Pkinase PF00069.20 EGC36562.1 - 7.3e-19 67.9 0.1 5.5e-17 61.7 0.1 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36562.1 - 9.6e-18 64.1 0.0 1.1e-15 57.4 0.0 2.2 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC36562.1 - 3.5e-05 23.6 0.0 4.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Fructosamin_kin PF03881.9 EGC36562.1 - 0.0015 17.5 0.0 0.0022 17.0 0.0 1.4 1 0 0 1 1 1 1 Fructosamine kinase P22_CoatProtein PF11651.3 EGC36562.1 - 0.17 10.4 0.0 3.5 6.1 0.0 2.0 2 0 0 2 2 2 0 P22 coat protein - gene protein 5 zf-C2H2 PF00096.21 EGC36563.1 - 0.004 17.4 0.3 0.012 15.9 0.2 1.9 1 0 0 1 1 1 1 Zinc finger, C2H2 type zf-C2H2_4 PF13894.1 EGC36563.1 - 0.042 14.1 1.3 0.087 13.1 0.2 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger DUF3439 PF11921.3 EGC36565.1 - 0.024 14.4 8.7 0.031 14.0 6.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Dicty_REP PF05086.7 EGC36565.1 - 0.025 12.3 7.5 0.025 12.3 5.2 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein BRF1 PF07741.8 EGC36565.1 - 0.073 13.3 0.2 0.11 12.7 0.2 1.2 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Mucin PF01456.12 EGC36565.1 - 0.22 11.2 16.2 0.28 10.9 11.3 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein Menin PF05053.8 EGC36565.1 - 0.63 8.1 4.5 0.81 7.7 3.1 1.1 1 0 0 1 1 1 0 Menin SSP160 PF06933.6 EGC36565.1 - 3.2 5.6 15.0 3.5 5.4 10.4 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC36566.1 - 0.003 17.3 6.2 0.0047 16.7 4.3 1.3 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 EGC36566.1 - 0.017 14.8 6.2 0.036 13.7 4.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) FF PF01846.14 EGC36566.1 - 0.019 14.8 2.1 0.57 10.1 0.2 2.7 2 0 0 2 2 2 0 FF domain SSP160 PF06933.6 EGC36566.1 - 0.05 11.5 7.4 0.068 11.1 5.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 SAPS PF04499.10 EGC36568.1 - 0.017 13.8 0.1 0.023 13.3 0.0 1.3 1 1 0 1 1 1 0 SIT4 phosphatase-associated protein DUF3439 PF11921.3 EGC36570.1 - 0.43 10.3 15.9 1.4 8.6 1.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tmpp129 PF10272.4 EGC36570.1 - 1.9 7.1 19.7 2.6 6.6 0.9 2.4 2 1 0 2 2 2 0 Putative transmembrane protein precursor Rtf2 PF04641.7 EGC36570.1 - 3 6.9 29.3 0.039 13.1 9.9 2.4 2 0 0 2 2 2 0 Rtf2 RING-finger Utp14 PF04615.8 EGC36570.1 - 3.8 5.5 33.1 0.82 7.7 13.1 2.2 2 0 0 2 2 2 0 Utp14 protein RR_TM4-6 PF06459.7 EGC36570.1 - 5.9 6.6 15.7 0.25 11.2 5.9 2.1 2 0 0 2 2 2 0 Ryanodine Receptor TM 4-6 Acetyltransf_7 PF13508.1 EGC36571.1 - 0.012 15.8 0.1 0.064 13.4 0.1 2.1 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC36571.1 - 0.021 14.8 0.0 0.041 13.9 0.0 1.6 1 1 0 1 1 1 0 Acetyltransferase (GNAT) family IP_trans PF02121.13 EGC36572.1 - 9.1e-102 339.5 0.3 1.1e-101 339.2 0.2 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein eRF1_1 PF03463.10 EGC36573.1 - 1.1e-43 148.0 0.6 2e-43 147.1 0.4 1.5 1 0 0 1 1 1 1 eRF1 domain 1 eRF1_2 PF03464.10 EGC36573.1 - 8.8e-27 94.0 0.1 1.6e-26 93.2 0.1 1.4 1 0 0 1 1 1 1 eRF1 domain 2 eRF1_3 PF03465.10 EGC36573.1 - 2.4e-26 92.2 0.1 5.7e-26 90.9 0.1 1.7 1 0 0 1 1 1 1 eRF1 domain 3 DUF1958 PF09211.5 EGC36573.1 - 0.075 13.1 1.5 0.51 10.4 0.1 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF1958) Acetyltransf_1 PF00583.19 EGC36574.1 - 3.1e-14 52.7 0.0 4.9e-08 32.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC36574.1 - 1.3e-11 44.4 0.0 8.4e-05 22.6 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC36574.1 - 2.9e-09 37.0 0.0 0.00015 21.8 0.0 2.3 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC36574.1 - 7.8e-08 32.5 0.0 0.013 15.6 0.0 2.2 2 0 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC36574.1 - 0.0013 18.5 0.0 1.2 8.9 0.0 2.9 2 1 0 2 2 2 2 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC36574.1 - 0.0014 18.5 0.0 0.061 13.2 0.0 2.4 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGC36574.1 - 0.0052 16.5 0.0 0.12 12.0 0.0 2.4 2 0 0 2 2 2 1 FR47-like protein Acetyltransf_4 PF13420.1 EGC36574.1 - 0.019 14.9 0.1 0.81 9.6 0.0 2.4 2 2 0 2 2 2 0 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC36574.1 - 0.042 13.7 0.0 0.18 11.6 0.0 2.0 2 0 0 2 2 2 0 Acetyltransferase (GNAT) domain Sec7 PF01369.15 EGC36575.1 - 1.6e-54 184.5 7.6 1.6e-54 184.5 5.3 3.9 4 0 0 4 4 4 1 Sec7 domain Sec7_N PF12783.2 EGC36575.1 - 7.9e-43 145.7 6.0 7.9e-43 145.7 4.2 4.8 5 0 0 5 5 5 1 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGC36575.1 - 2.2e-27 94.3 1.7 2.2e-27 94.3 1.2 3.7 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF1664 PF07889.7 EGC36575.1 - 0.29 10.9 13.3 1.1 9.0 9.2 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) PH PF00169.24 EGC36576.1 - 1e-05 25.6 2.4 1e-05 25.6 1.6 2.8 2 0 0 2 2 2 1 PH domain Helicase_C PF00271.26 EGC36577.1 - 1.2e-15 57.1 0.0 3.9e-15 55.4 0.0 1.9 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC36577.1 - 4.7e-14 52.2 0.1 8.2e-13 48.1 0.0 2.5 2 0 0 2 2 2 1 DEAD/DEAH box helicase ResIII PF04851.10 EGC36577.1 - 6.6e-13 48.8 0.0 6.6e-13 48.8 0.0 3.6 2 2 0 2 2 2 1 Type III restriction enzyme, res subunit dsrm PF00035.20 EGC36577.1 - 4.9e-08 33.4 1.5 7.5e-05 23.2 0.0 3.0 3 0 0 3 3 3 2 Double-stranded RNA binding motif MFMR PF07777.6 EGC36577.1 - 9.2 6.1 7.7 21 4.9 5.3 1.6 1 0 0 1 1 1 0 G-box binding protein MFMR Phi-29_GP4 PF05464.6 EGC36578.1 - 0.026 14.3 0.8 0.026 14.3 0.5 2.1 1 1 1 2 2 2 0 Phi-29-like late genes activator (early protein GP4) ATG16 PF08614.6 EGC36578.1 - 3.4 7.4 21.6 0.55 10.0 10.8 2.4 2 1 0 2 2 2 0 Autophagy protein 16 (ATG16) DivIVA PF05103.8 EGC36578.1 - 4.9 7.2 20.5 0.28 11.2 4.4 2.7 1 1 1 2 2 2 0 DivIVA protein DUF3502 PF12010.3 EGC36580.1 - 0.011 15.7 0.2 0.073 13.0 0.1 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3502) ParB PF08775.5 EGC36580.1 - 0.015 15.6 0.3 0.015 15.6 0.2 2.0 2 1 1 3 3 3 0 ParB family YodL PF14191.1 EGC36580.1 - 0.093 13.2 0.3 0.31 11.5 0.1 2.0 1 1 1 2 2 2 0 YodL-like THOC7 PF05615.8 EGC36580.1 - 0.49 10.6 3.9 0.53 10.5 1.3 2.0 1 1 1 2 2 2 0 Tho complex subunit 7 Ribosomal_S13 PF00416.17 EGC36581.1 - 8.9 6.8 8.7 0.24 11.8 0.9 2.2 3 0 0 3 3 3 0 Ribosomal protein S13/S18 DUF3907 PF13047.1 EGC36582.1 - 0.65 9.6 4.6 0.83 9.2 3.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) DUF357 PF04010.8 EGC36582.1 - 1 9.0 4.0 6.4 6.5 2.8 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF357) PLAC8 PF04749.12 EGC36584.1 - 1.6e-18 67.2 14.9 1.8e-18 67.0 10.3 1.0 1 0 0 1 1 1 1 PLAC8 family NAP PF00956.13 EGC36585.1 - 8.3e-06 25.0 15.6 2e-05 23.8 10.8 1.6 1 1 0 1 1 1 1 Nucleosome assembly protein (NAP) Sel1 PF08238.7 EGC36588.1 - 1.2e-16 60.7 9.2 1.3e-06 28.8 0.4 5.0 5 0 0 5 5 5 4 Sel1 repeat TPR_6 PF13174.1 EGC36588.1 - 0.0011 19.2 0.1 0.28 11.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC36589.1 - 5.8e-12 45.1 8.2 0.024 15.2 0.0 8.8 6 3 3 9 9 9 4 Tetratricopeptide repeat TPR_11 PF13414.1 EGC36589.1 - 6.2e-10 38.5 3.7 0.045 13.3 0.0 5.4 5 0 0 5 5 5 3 TPR repeat TPR_2 PF07719.12 EGC36589.1 - 0.00012 21.6 16.4 0.76 9.8 0.0 7.9 9 0 0 9 9 9 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC36589.1 - 0.00013 22.4 16.1 0.35 11.6 0.0 6.6 6 1 2 8 8 8 2 Tetratricopeptide repeat Suf PF05843.9 EGC36589.1 - 0.00015 21.6 0.4 0.00015 21.6 0.3 6.1 5 1 1 6 6 6 2 Suppressor of forked protein (Suf) TPR_17 PF13431.1 EGC36589.1 - 0.00022 21.1 0.1 0.18 12.0 0.0 5.0 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC36589.1 - 0.00031 21.0 15.8 0.72 10.2 0.0 6.6 5 2 2 7 7 7 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC36589.1 - 0.0016 18.0 8.5 2.9 7.8 0.0 5.9 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC36589.1 - 0.025 14.3 2.6 13 5.8 0.0 4.3 4 0 0 4 4 4 0 Tetratricopeptide repeat Macoilin PF09726.4 EGC36589.1 - 0.42 8.8 39.5 0.61 8.3 27.4 1.2 1 0 0 1 1 1 0 Transmembrane protein CUE PF02845.11 EGC36590.1 - 6.6e-11 41.4 0.0 1.9e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 CUE domain F5_F8_type_C PF00754.20 EGC36591.1 - 5.9e-06 26.1 0.2 1.1e-05 25.2 0.1 1.5 1 1 0 1 1 1 1 F5/8 type C domain Sad1_UNC PF07738.8 EGC36591.1 - 0.0069 16.1 0.8 0.013 15.2 0.6 1.5 1 1 0 1 1 1 1 Sad1 / UNC-like C-terminal APC10 PF03256.11 EGC36591.1 - 0.054 13.0 0.0 0.14 11.6 0.0 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex, subunit 10 (APC10) DUF3599 PF12206.3 EGC36591.1 - 0.1 12.8 1.5 0.17 12.1 0.4 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF3599) ABC2_membrane PF01061.19 EGC36592.1 - 5.6e-37 126.9 17.8 5.6e-37 126.9 12.4 1.4 2 0 0 2 2 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC36592.1 - 2.7e-25 89.2 0.0 1.8e-24 86.5 0.0 2.0 2 0 0 2 2 2 1 ABC transporter ABC2_membrane_3 PF12698.2 EGC36592.1 - 5.4e-06 25.6 14.4 8.1e-06 25.0 10.0 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGC36592.1 - 8.6e-06 25.9 1.8 8.6e-06 25.9 1.2 3.8 2 2 0 3 3 3 1 AAA domain AAA_25 PF13481.1 EGC36592.1 - 0.00093 18.6 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC36592.1 - 0.0012 18.8 0.1 0.0027 17.7 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain DUF258 PF03193.11 EGC36592.1 - 0.0016 17.6 0.1 0.0027 16.9 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 NTPase_1 PF03266.10 EGC36592.1 - 0.0031 17.2 0.2 0.1 12.2 0.1 2.3 2 0 0 2 2 2 1 NTPase AAA_19 PF13245.1 EGC36592.1 - 0.0071 16.0 0.0 0.015 15.0 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_22 PF13401.1 EGC36592.1 - 0.0092 16.1 0.5 0.28 11.3 0.6 2.8 2 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGC36592.1 - 0.011 15.7 0.3 0.017 15.1 0.2 1.2 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGC36592.1 - 0.012 15.1 0.4 0.044 13.2 0.3 1.8 2 0 0 2 2 2 0 AAA-like domain AAA_15 PF13175.1 EGC36592.1 - 0.018 14.1 6.8 0.79 8.6 0.1 3.0 3 0 0 3 3 3 0 AAA ATPase domain AAA_29 PF13555.1 EGC36592.1 - 0.024 14.1 0.2 0.047 13.2 0.2 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EGC36592.1 - 0.024 14.2 0.0 0.047 13.3 0.0 1.5 1 0 0 1 1 1 0 NACHT domain MMR_HSR1 PF01926.18 EGC36592.1 - 0.033 14.1 0.2 0.09 12.7 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_18 PF13238.1 EGC36592.1 - 0.036 14.3 0.0 0.075 13.3 0.0 1.5 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGC36592.1 - 0.044 12.6 0.2 0.078 11.8 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein FtsK_SpoIIIE PF01580.13 EGC36592.1 - 0.062 12.7 0.2 0.11 11.9 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EGC36592.1 - 0.083 13.7 0.0 0.23 12.2 0.0 1.8 2 0 0 2 2 1 0 AAA domain SMC_N PF02463.14 EGC36592.1 - 0.084 12.0 0.3 5.8 6.0 0.0 2.2 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain AAA_30 PF13604.1 EGC36592.1 - 0.23 11.0 0.1 0.39 10.2 0.0 1.2 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGC36592.1 - 0.23 11.7 3.5 1.3 9.2 0.7 2.3 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGC36592.1 - 0.27 11.0 1.5 0.26 11.0 0.1 1.6 2 0 0 2 2 1 0 Domain of unknown function DUF87 Img2 PF05046.9 EGC36593.1 - 1.5e-12 47.5 0.0 3.1e-12 46.5 0.0 1.5 1 0 0 1 1 1 1 Mitochondrial large subunit ribosomal protein (Img2) L51_S25_CI-B8 PF05047.11 EGC36593.1 - 0.046 13.4 0.1 0.087 12.5 0.1 1.6 1 1 0 1 1 1 0 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain AFP PF02420.10 EGC36596.1 - 0.014 15.4 0.4 0.067 13.3 0.3 2.2 1 0 0 1 1 1 0 Insect antifreeze protein repeat Ocnus PF05005.10 EGC36597.1 - 9.1e-19 67.3 0.0 1.4e-18 66.7 0.0 1.3 1 1 0 1 1 1 1 Janus/Ocnus family (Ocnus) Transket_pyr PF02779.19 EGC36599.1 - 4.9e-58 195.5 0.0 8.8e-58 194.7 0.0 1.4 1 0 0 1 1 1 1 Transketolase, pyrimidine binding domain E1_dh PF00676.15 EGC36599.1 - 1e-42 145.8 0.0 1.8e-42 145.1 0.0 1.3 1 0 0 1 1 1 1 Dehydrogenase E1 component DUF3574 PF12098.3 EGC36599.1 - 0.075 12.6 0.2 0.48 10.0 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3574) SWIRM PF04433.12 EGC36599.1 - 0.23 11.6 2.6 0.55 10.3 0.0 2.8 3 0 0 3 3 3 0 SWIRM domain G-alpha PF00503.15 EGC36600.1 - 2.5e-91 306.2 16.9 3e-91 306.0 11.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC36600.1 - 1.7e-12 46.9 0.1 1.2e-09 37.7 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGC36600.1 - 1.5e-07 31.9 0.8 0.015 15.7 0.0 2.9 3 1 0 3 3 3 2 Miro-like protein Gtr1_RagA PF04670.7 EGC36600.1 - 1e-05 24.7 6.3 0.00025 20.2 0.4 2.5 1 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Ras PF00071.17 EGC36600.1 - 0.00016 21.0 1.1 0.16 11.3 0.1 2.5 2 1 0 2 2 2 2 Ras family MMR_HSR1 PF01926.18 EGC36600.1 - 0.0017 18.2 0.1 0.19 11.7 0.1 2.8 1 1 0 1 1 1 1 50S ribosome-binding GTPase AKNA PF12443.3 EGC36600.1 - 0.033 14.2 0.1 0.12 12.3 0.0 1.9 2 0 0 2 2 2 0 AT-hook-containing transcription factor GTP_EFTU PF00009.22 EGC36600.1 - 0.066 12.6 0.9 0.96 8.8 0.1 2.6 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain ATP_bind_1 PF03029.12 EGC36600.1 - 0.11 12.0 1.1 0.25 10.8 0.0 2.1 3 0 0 3 3 3 0 Conserved hypothetical ATP binding protein PPR_2 PF13041.1 EGC36601.1 - 3.3e-06 26.9 4.4 0.32 11.0 0.0 5.8 5 1 1 6 6 6 2 PPR repeat family PPR PF01535.15 EGC36601.1 - 0.00097 18.9 3.9 3.3 7.8 0.0 4.9 5 0 0 5 5 5 2 PPR repeat TPR_19 PF14559.1 EGC36601.1 - 0.012 15.8 1.3 9.9 6.5 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC36601.1 - 0.12 12.4 2.2 21 5.3 0.2 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat Myb_Cef PF11831.3 EGC36602.1 - 2.2e-37 128.4 22.9 2.2e-37 128.4 15.9 3.2 3 1 0 3 3 3 1 pre-mRNA splicing factor component Myb_DNA-binding PF00249.26 EGC36602.1 - 7.7e-20 70.6 4.1 2e-09 37.3 0.2 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC36602.1 - 1.2e-17 63.7 5.4 8.4e-13 48.2 2.4 3.1 1 1 1 2 2 2 2 Myb-like DNA-binding domain GYF PF02213.11 EGC36603.1 - 6.6e-17 60.8 0.1 6.6e-17 60.8 0.0 3.8 2 1 0 2 2 2 1 GYF domain Peptidase_C48 PF02902.14 EGC36604.1 - 3.4e-15 56.2 0.5 1.4e-14 54.2 0.4 1.8 1 1 0 1 1 1 1 Ulp1 protease family, C-terminal catalytic domain SAP PF02037.22 EGC36605.1 - 1e-08 34.4 0.1 2.2e-08 33.4 0.1 1.6 1 0 0 1 1 1 1 SAP domain zf-C3HC4 PF00097.20 EGC36605.1 - 3.6e-07 29.7 11.7 3.6e-07 29.7 8.1 3.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC36605.1 - 7e-07 28.9 12.3 1.4e-06 27.9 6.8 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC36605.1 - 1.2e-05 25.2 11.2 1.2e-05 25.2 7.8 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC36605.1 - 1.8e-05 24.2 13.6 2.6e-05 23.7 7.3 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC36605.1 - 7.7e-05 22.4 19.9 0.00019 21.2 7.9 3.0 3 0 0 3 3 3 2 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC36605.1 - 0.00031 20.3 9.8 0.00031 20.3 6.8 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC36605.1 - 0.13 12.3 10.3 0.1 12.7 4.4 2.6 2 1 0 2 2 2 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC36605.1 - 0.39 10.4 13.4 0.1 12.3 5.9 2.7 2 0 0 2 2 2 0 RING-type zinc-finger START PF01852.14 EGC36606.1 - 6.1e-08 32.2 0.0 2.8e-07 30.0 0.0 2.0 1 1 1 2 2 2 1 START domain Uso1_p115_C PF04871.8 EGC36606.1 - 0.057 13.3 3.1 0.13 12.2 2.1 1.5 1 0 0 1 1 1 0 Uso1 / p115 like vesicle tethering protein, C terminal region DUF2120 PF09893.4 EGC36606.1 - 0.06 13.3 1.0 0.13 12.2 0.7 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2120) Pkinase PF00069.20 EGC36607.1 - 4.3e-65 219.4 0.5 2.6e-42 144.7 0.0 3.0 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36607.1 - 2.5e-31 108.6 0.1 4.5e-22 78.3 0.0 2.4 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC36607.1 - 0.00029 19.9 0.1 0.0089 15.0 0.0 2.7 1 1 1 2 2 2 1 Kinase-like APH PF01636.18 EGC36607.1 - 0.0038 16.9 0.1 0.25 11.0 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family Kdo PF06293.9 EGC36607.1 - 0.028 13.4 0.0 0.048 12.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TAFII28 PF04719.9 EGC36608.1 - 5.7e-32 109.3 0.3 6.4e-32 109.2 0.2 1.0 1 0 0 1 1 1 1 hTAFII28-like protein conserved region CBFD_NFYB_HMF PF00808.18 EGC36608.1 - 0.02 14.9 0.0 0.028 14.4 0.0 1.4 1 0 0 1 1 1 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone dCMP_cyt_deam_1 PF00383.17 EGC36609.1 - 2.3e-10 40.0 0.3 2.8e-09 36.5 0.2 2.2 1 1 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC36609.1 - 0.0052 16.6 0.0 0.012 15.5 0.0 1.5 1 0 0 1 1 1 1 Bd3614-like deaminase Pro_Al_protease PF02983.9 EGC36609.1 - 0.098 12.6 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Alpha-lytic protease prodomain OTT_1508_deam PF14441.1 EGC36609.1 - 0.11 12.3 1.6 0.53 10.0 0.0 2.4 2 0 0 2 2 2 0 OTT_1508-like deaminase CTDII PF01556.13 EGC36610.1 - 9.9e-35 118.2 8.9 9.3e-24 83.1 0.5 3.5 2 1 0 3 3 3 3 DnaJ C terminal domain DnaJ PF00226.26 EGC36610.1 - 5.2e-24 83.7 2.0 9.9e-24 82.8 1.4 1.5 1 0 0 1 1 1 1 DnaJ domain DnaJ_CXXCXGXG PF00684.14 EGC36610.1 - 2.4e-13 49.9 21.7 5.1e-13 48.8 15.0 1.6 1 0 0 1 1 1 1 DnaJ central domain TPR_11 PF13414.1 EGC36611.1 - 2.7e-10 39.7 5.0 0.017 14.7 0.8 4.0 2 2 1 3 3 3 3 TPR repeat TPR_16 PF13432.1 EGC36611.1 - 7.6e-10 39.2 0.0 0.0024 18.4 0.0 4.0 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC36611.1 - 3.1e-09 35.9 5.6 0.0011 18.5 0.0 4.6 3 1 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC36611.1 - 2.5e-08 33.1 6.1 0.063 13.2 0.0 5.3 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC36611.1 - 7.7e-07 29.3 0.0 0.061 13.6 0.0 3.3 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC36611.1 - 3.1e-06 26.5 5.1 0.031 13.8 0.0 3.9 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC36611.1 - 5.7e-06 26.4 0.1 15 6.5 0.0 5.0 4 1 1 5 5 5 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC36611.1 - 0.00023 21.0 0.4 0.073 13.0 0.1 3.3 2 2 2 4 4 4 1 Tetratricopeptide repeat TOM20_plant PF06552.7 EGC36611.1 - 0.001 18.6 6.2 0.0045 16.5 0.8 2.8 1 1 1 3 3 3 1 Plant specific mitochondrial import receptor subunit TOM20 TPR_17 PF13431.1 EGC36611.1 - 0.004 17.2 0.6 6.7 7.1 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat DUF627 PF04781.7 EGC36611.1 - 0.0044 16.6 0.3 0.11 12.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF627) HTH_Tnp_Mu_1 PF02316.11 EGC36611.1 - 0.048 13.3 0.1 0.08 12.6 0.0 1.3 1 0 0 1 1 1 0 Mu DNA-binding domain DUF1310 PF07006.6 EGC36611.1 - 0.094 12.2 0.1 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1310) TPR_7 PF13176.1 EGC36611.1 - 0.13 12.1 0.2 7.7 6.5 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC36611.1 - 0.34 11.4 1.6 16 6.1 0.0 3.6 3 1 0 3 3 3 0 Tetratricopeptide repeat REJ PF02010.10 EGC36612.1 - 6.7e-57 192.7 13.8 1.5e-52 178.3 7.0 2.4 1 1 1 2 2 2 2 REJ domain Glycos_transf_2 PF00535.21 EGC36612.1 - 2.4e-26 92.4 0.2 7e-26 90.9 0.2 1.8 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EGC36612.1 - 4.5e-16 58.7 1.4 1.5e-15 57.0 0.9 1.9 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glycos_transf_1 PF00534.15 EGC36612.1 - 1e-12 47.7 0.0 2.3e-11 43.4 0.0 3.1 4 0 0 4 4 3 1 Glycosyl transferases group 1 GPS PF01825.16 EGC36612.1 - 1.7e-12 47.2 6.1 1.7e-12 47.2 4.2 1.9 2 0 0 2 2 1 1 Latrophilin/CL-1-like GPS domain TIG PF01833.19 EGC36612.1 - 4.1e-12 45.9 1.9 4.1e-12 45.9 1.3 4.8 3 2 0 3 3 3 1 IPT/TIG domain Glyco_tranf_2_3 PF13641.1 EGC36612.1 - 1.4e-08 34.8 0.0 4e-08 33.3 0.0 1.8 2 0 0 2 2 1 1 Glycosyltransferase like family 2 Glyco_trans_4_4 PF13579.1 EGC36612.1 - 1.3e-07 31.9 0.0 2e-07 31.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_4 PF13692.1 EGC36612.1 - 1e-06 28.9 0.0 2.8e-06 27.5 0.0 1.7 1 0 0 1 1 1 1 Glycosyl transferases group 1 DUF1191 PF06697.7 EGC36612.1 - 1.3e-05 24.2 0.3 2.3e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1191) Glyco_trans_4_2 PF13477.1 EGC36612.1 - 7.7e-05 22.5 0.3 0.00034 20.4 0.0 2.3 2 0 0 2 2 1 1 Glycosyl transferase 4-like Glyco_transf_7C PF02709.9 EGC36612.1 - 0.00017 20.9 0.0 0.0004 19.7 0.0 1.5 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase DUF1510 PF07423.6 EGC36612.1 - 0.00023 20.6 18.3 0.00046 19.6 12.7 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Protocadherin PF08374.6 EGC36612.1 - 0.0014 18.3 8.2 0.0034 17.0 5.7 1.6 1 0 0 1 1 1 1 Protocadherin Glyco_transf_4 PF13439.1 EGC36612.1 - 0.01 15.5 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 0 Glycosyltransferase Family 4 Glyco_transf_5 PF08323.6 EGC36612.1 - 0.011 15.2 0.0 0.057 12.9 0.0 2.3 2 0 0 2 2 2 0 Starch synthase catalytic domain IncA PF04156.9 EGC36612.1 - 0.023 14.3 0.4 0.06 12.9 0.3 1.7 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EGC36612.1 - 0.037 14.4 1.8 0.15 12.4 1.3 2.1 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_tranf_2_5 PF13712.1 EGC36612.1 - 0.051 12.8 3.5 0.33 10.1 0.1 2.6 2 1 1 3 3 2 0 Glycosyltransferase like family Glyco_transf_21 PF13506.1 EGC36612.1 - 0.089 12.0 0.0 0.18 11.0 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase family 21 Peptidase_S49_N PF08496.5 EGC36612.1 - 0.11 12.3 11.1 0.34 10.6 7.7 1.8 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Glyco_tranf_2_4 PF13704.1 EGC36612.1 - 0.14 12.4 0.0 0.35 11.2 0.0 1.6 1 0 0 1 1 1 0 Glycosyl transferase family 2 FAM176 PF14851.1 EGC36612.1 - 1.2 8.8 8.4 12 5.5 5.8 2.4 1 1 0 1 1 1 0 FAM176 family MIP-T3 PF10243.4 EGC36612.1 - 3.2 6.1 34.7 4.9 5.4 24.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 ATP_bind_1 PF03029.12 EGC36613.1 - 3.8e-77 259.0 0.0 5.1e-77 258.6 0.0 1.2 1 0 0 1 1 1 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGC36613.1 - 1.4e-05 25.8 0.6 0.00025 21.8 0.4 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC36613.1 - 0.0017 18.0 0.0 0.0028 17.3 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 EGC36613.1 - 0.0021 17.5 0.0 0.0038 16.6 0.0 1.4 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_10 PF12846.2 EGC36613.1 - 0.0025 17.2 0.0 0.0041 16.5 0.0 1.3 1 0 0 1 1 1 1 AAA-like domain ArgK PF03308.11 EGC36613.1 - 0.0036 16.1 0.0 0.0059 15.4 0.0 1.2 1 0 0 1 1 1 1 ArgK protein MMR_HSR1 PF01926.18 EGC36613.1 - 0.01 15.8 0.0 0.026 14.4 0.0 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_31 PF13614.1 EGC36613.1 - 0.018 15.0 0.0 0.1 12.5 0.0 2.3 2 1 1 3 3 3 0 AAA domain KTI12 PF08433.5 EGC36613.1 - 0.024 13.8 0.0 0.046 12.9 0.0 1.4 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_18 PF13238.1 EGC36613.1 - 0.027 14.7 1.1 0.18 12.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain RNA_helicase PF00910.17 EGC36613.1 - 0.054 13.6 0.0 0.21 11.7 0.0 2.0 2 0 0 2 2 2 0 RNA helicase AAA PF00004.24 EGC36613.1 - 0.083 13.0 0.0 0.16 12.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC36613.1 - 0.089 12.9 0.0 0.18 11.9 0.0 1.5 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGC36613.1 - 0.094 12.4 0.0 0.21 11.2 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGC36613.1 - 0.11 11.9 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGC36613.1 - 0.13 11.1 0.0 0.21 10.4 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein GCV_H PF01597.14 EGC36614.1 - 0.007 16.0 0.4 0.12 12.0 0.3 2.5 1 1 0 1 1 1 1 Glycine cleavage H-protein UQ_con PF00179.21 EGC36615.1 - 5.5e-49 165.2 0.0 6.2e-49 165.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC36615.1 - 1e-05 25.3 0.0 1.3e-05 25.0 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B RWD PF05773.17 EGC36615.1 - 0.0033 17.3 0.2 0.0038 17.1 0.1 1.4 1 1 0 1 1 1 1 RWD domain UEV PF05743.8 EGC36615.1 - 0.047 13.3 0.0 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 UEV domain CDP-OH_P_transf PF01066.16 EGC36616.1 - 2.2e-17 63.2 11.9 2.2e-17 63.2 8.2 2.6 2 1 0 2 2 2 1 CDP-alcohol phosphatidyltransferase HOK_GEF PF01848.11 EGC36616.1 - 1.1 8.6 8.1 1.2 8.5 0.7 2.7 2 0 0 2 2 2 0 Hok/gef family DUF3128 PF11326.3 EGC36617.1 - 5.1e-08 32.9 0.6 1.2e-07 31.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3128) DUF4078 PF13300.1 EGC36617.1 - 0.41 10.7 5.0 1.1 9.4 3.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4078) PigN PF04987.9 EGC36618.1 - 5.6e-116 387.7 48.7 8e-116 387.2 33.7 1.2 1 0 0 1 1 1 1 Phosphatidylinositolglycan class N (PIG-N) Phosphodiest PF01663.17 EGC36618.1 - 1.8e-15 57.1 0.0 4.5e-09 36.0 0.1 2.2 1 1 1 2 2 2 2 Type I phosphodiesterase / nucleotide pyrophosphatase Sulfatase PF00884.18 EGC36618.1 - 1.6e-05 24.2 0.0 3.3e-05 23.2 0.0 1.5 1 0 0 1 1 1 1 Sulfatase IPK PF03770.11 EGC36619.1 - 3.2e-35 121.5 4.1 3.2e-35 121.5 2.9 3.0 2 1 0 2 2 2 1 Inositol polyphosphate kinase 3Beta_HSD PF01073.14 EGC36620.1 - 1.1e-31 109.5 0.2 1.5e-31 109.1 0.2 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC36620.1 - 4.1e-27 95.1 0.0 5.4e-27 94.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGC36620.1 - 6.2e-27 94.1 0.0 9.1e-27 93.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGC36620.1 - 3.7e-15 56.4 0.0 5.2e-15 55.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC36620.1 - 4.2e-12 45.5 0.0 8.3e-12 44.5 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC36620.1 - 5.6e-11 41.8 0.0 8.1e-11 41.3 0.0 1.5 1 1 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC36620.1 - 6.3e-08 32.7 0.0 1.3e-07 31.6 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGC36620.1 - 2.1e-07 30.4 0.0 2.9e-07 30.0 0.0 1.3 1 1 0 1 1 1 1 NmrA-like family KR PF08659.5 EGC36620.1 - 0.00013 21.7 0.0 0.0021 17.7 0.0 2.2 1 1 0 1 1 1 1 KR domain NAD_binding_3 PF03447.11 EGC36620.1 - 0.031 14.6 0.0 4.2 7.7 0.0 2.5 2 0 0 2 2 2 0 Homoserine dehydrogenase, NAD binding domain Semialdhyde_dh PF01118.19 EGC36620.1 - 0.075 13.3 0.0 0.21 11.9 0.0 1.8 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain PA14 PF07691.7 EGC36621.1 - 7.9e-10 38.5 0.0 1.4e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC36621.1 - 0.0024 17.6 6.1 0.0024 17.6 4.2 6.0 5 1 1 6 6 6 2 Dictyostelium (slime mold) repeat PT PF04886.7 EGC36621.1 - 2.1 7.7 18.4 4.4 6.7 12.8 1.5 1 0 0 1 1 1 0 PT repeat Proteasome PF00227.21 EGC36622.1 - 1.2e-47 161.6 0.0 1.5e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC36622.1 - 4.2e-11 41.9 0.1 6.4e-11 41.3 0.1 1.3 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Homeobox PF00046.24 EGC36622.1 - 0.052 13.1 0.1 0.1 12.2 0.1 1.5 1 0 0 1 1 1 0 Homeobox domain ETF_QO PF05187.8 EGC36623.1 - 5.9e-40 135.6 0.0 9.6e-40 135.0 0.0 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein-ubiquinone oxidoreductase FAD_binding_2 PF00890.19 EGC36623.1 - 4.2e-09 35.7 0.3 1.1e-05 24.4 0.6 2.1 2 0 0 2 2 2 2 FAD binding domain DAO PF01266.19 EGC36623.1 - 5.4e-09 35.4 1.3 0.00093 18.1 0.7 2.2 1 1 0 2 2 2 2 FAD dependent oxidoreductase NAD_binding_8 PF13450.1 EGC36623.1 - 2e-06 27.7 0.0 9.4e-06 25.5 0.0 2.1 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain Thi4 PF01946.12 EGC36623.1 - 8.2e-06 25.0 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thi4 family Pyr_redox_2 PF07992.9 EGC36623.1 - 2.4e-05 24.3 0.2 4.9e-05 23.2 0.1 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGC36623.1 - 0.00011 20.8 0.7 0.00023 19.7 0.5 1.5 2 0 0 2 2 2 1 HI0933-like protein Lycopene_cycl PF05834.7 EGC36623.1 - 0.00015 20.8 0.3 0.00021 20.3 0.2 1.2 1 0 0 1 1 1 1 Lycopene cyclase protein Pyr_redox_3 PF13738.1 EGC36623.1 - 0.00018 21.6 0.0 0.0003 20.9 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGC36623.1 - 0.0005 19.8 0.0 0.00081 19.1 0.0 1.4 1 0 0 1 1 1 1 FAD-NAD(P)-binding FAD_oxidored PF12831.2 EGC36623.1 - 0.0025 16.9 0.0 0.0032 16.5 0.0 1.2 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGC36623.1 - 0.0026 16.8 0.2 0.0044 16.1 0.1 1.4 1 1 0 1 1 1 1 FAD binding domain Pyr_redox PF00070.22 EGC36623.1 - 0.007 16.7 0.0 0.36 11.2 0.0 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Trp_halogenase PF04820.9 EGC36623.1 - 0.012 14.3 0.0 0.88 8.1 0.1 2.1 2 0 0 2 2 2 0 Tryptophan halogenase Fer4_7 PF12838.2 EGC36623.1 - 0.033 14.5 0.7 0.083 13.2 0.5 1.6 1 0 0 1 1 1 0 4Fe-4S dicluster domain K_oxygenase PF13434.1 EGC36623.1 - 0.051 12.4 0.0 0.077 11.9 0.0 1.2 1 0 0 1 1 1 0 L-lysine 6-monooxygenase (NADPH-requiring) GIDA PF01134.17 EGC36623.1 - 0.084 11.7 0.0 0.13 11.1 0.0 1.2 1 0 0 1 1 1 0 Glucose inhibited division protein A DUF3430 PF11912.3 EGC36624.1 - 1.9e-26 93.2 17.3 2.1e-26 93.0 12.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) COX15-CtaA PF02628.10 EGC36625.1 - 1.6e-95 319.4 2.8 2.3e-95 318.9 1.9 1.2 1 0 0 1 1 1 1 Cytochrome oxidase assembly protein LIM_bind PF01803.11 EGC36625.1 - 0.036 13.1 6.1 0.056 12.5 4.3 1.2 1 0 0 1 1 1 0 LIM-domain binding protein DUF3528 PF12045.3 EGC36625.1 - 0.057 13.5 3.1 0.09 12.9 2.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3528) Serinc PF03348.10 EGC36625.1 - 0.074 11.7 0.2 0.12 11.0 0.1 1.3 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF1980 PF09323.5 EGC36625.1 - 0.19 11.4 9.1 0.38 10.4 6.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Peptidase_S49_N PF08496.5 EGC36625.1 - 0.66 9.7 5.4 1.2 8.9 3.8 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal CopD PF05425.8 EGC36625.1 - 0.79 9.9 0.0 0.79 9.9 0.0 3.8 3 1 0 3 3 3 0 Copper resistance protein D DDHD PF02862.12 EGC36625.1 - 3.3 7.4 9.2 5.1 6.8 6.3 1.2 1 0 0 1 1 1 0 DDHD domain PBP_sp32 PF07222.7 EGC36625.1 - 4.2 6.4 9.5 7 5.7 6.6 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 SNF2_N PF00176.18 EGC36626.1 - 6.8e-27 94.0 0.0 1.2e-26 93.2 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC36626.1 - 2.5e-08 33.6 0.0 6.8e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC36626.1 - 1.4e-06 27.9 0.1 0.0021 17.5 0.0 3.2 2 1 0 2 2 2 2 DEAD/DEAH box helicase ResIII PF04851.10 EGC36626.1 - 0.00072 19.4 0.0 0.49 10.1 0.0 3.7 2 2 1 3 3 3 1 Type III restriction enzyme, res subunit HARP PF07443.8 EGC36626.1 - 0.12 11.8 0.1 0.25 10.7 0.0 1.6 1 0 0 1 1 1 0 HepA-related protein (HARP) Flavi_DEAD PF07652.9 EGC36626.1 - 0.14 11.9 0.0 0.29 10.8 0.0 1.5 1 0 0 1 1 1 0 Flavivirus DEAD domain DZR PF12773.2 EGC36627.1 - 0.0012 18.5 7.5 0.0024 17.6 1.4 2.4 2 0 0 2 2 2 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EGC36627.1 - 0.051 12.7 12.5 1.7 7.9 0.1 2.4 2 0 0 2 2 2 0 zinc-ribbon domain SLY PF12485.3 EGC36627.1 - 0.053 13.7 5.5 0.075 13.2 3.8 1.1 1 0 0 1 1 1 0 Lymphocyte signaling adaptor protein YlzJ PF14035.1 EGC36627.1 - 0.073 13.1 0.0 0.13 12.3 0.0 1.3 1 0 0 1 1 1 0 YlzJ-like protein zinc_ribbon_2 PF13240.1 EGC36627.1 - 0.19 11.2 11.8 1.1 8.8 3.6 2.9 2 1 0 2 2 2 0 zinc-ribbon domain DUF4451 PF14616.1 EGC36627.1 - 0.26 11.0 3.6 0.15 11.8 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) zf-ISL3 PF14690.1 EGC36627.1 - 0.3 11.1 0.2 0.3 11.1 0.1 2.4 2 0 0 2 2 2 0 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 Ehrlichia_rpt PF09528.5 EGC36627.1 - 0.38 8.8 4.0 0.23 9.5 0.2 1.9 2 0 0 2 2 2 0 Ehrlichia tandem repeat (Ehrlichia_rpt) PGM_PMM_I PF02878.11 EGC36628.1 - 6.1e-29 100.2 0.0 4.3e-28 97.5 0.0 2.3 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I PGM_PMM_II PF02879.11 EGC36628.1 - 1.1e-24 86.7 0.0 2.4e-24 85.6 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II PGM_PMM_III PF02880.11 EGC36628.1 - 3.6e-17 62.4 0.0 7.9e-17 61.3 0.0 1.6 1 0 0 1 1 1 1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III PGM_PMM_IV PF00408.15 EGC36628.1 - 1.1e-08 34.9 0.1 3.8e-08 33.2 0.0 1.9 2 0 0 2 2 2 1 Phosphoglucomutase/phosphomannomutase, C-terminal domain ComC PF03047.9 EGC36629.1 - 0.024 14.0 5.2 0.038 13.4 0.7 3.0 2 0 0 2 2 2 0 COMC family MFS_1 PF07690.11 EGC36630.1 - 9.7e-51 172.5 17.8 5.4e-44 150.3 3.7 2.2 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC36630.1 - 1.1e-11 43.9 22.7 1.9e-08 33.3 7.1 2.2 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_3 PF05977.8 EGC36630.1 - 0.0098 14.0 16.9 0.017 13.2 2.4 2.1 2 0 0 2 2 2 2 Transmembrane secretion effector PS_Dcarbxylase PF02666.10 EGC36631.1 - 3.7e-56 189.6 0.0 6.5e-56 188.8 0.0 1.4 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase C2 PF00168.25 EGC36631.1 - 9.3e-23 79.8 0.6 2.1e-22 78.7 0.1 1.8 2 0 0 2 2 2 1 C2 domain EF-hand_7 PF13499.1 EGC36631.1 - 4.2e-05 23.5 2.4 0.0054 16.8 0.1 2.2 1 1 1 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC36631.1 - 0.00015 20.8 0.1 0.00052 19.1 0.1 2.1 1 0 0 1 1 1 1 EF hand EF-hand_6 PF13405.1 EGC36631.1 - 0.0086 15.8 0.2 0.046 13.6 0.0 2.3 2 0 0 2 2 2 1 EF-hand domain EF-hand_8 PF13833.1 EGC36631.1 - 0.015 14.9 0.0 0.041 13.5 0.0 1.8 1 0 0 1 1 1 0 EF-hand domain pair Biotin_lipoyl_2 PF13533.1 EGC36631.1 - 0.033 13.8 0.0 0.09 12.4 0.0 1.7 1 0 0 1 1 1 0 Biotin-lipoyl like DEAD PF00270.24 EGC36632.1 - 6e-34 116.9 0.4 6e-34 116.9 0.3 3.3 4 1 0 4 4 4 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC36632.1 - 4.1e-25 87.4 1.0 3.7e-24 84.3 0.3 2.7 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Prothymosin PF03247.9 EGC36632.1 - 0.00046 20.2 21.8 0.00046 20.2 15.1 6.4 6 0 0 6 6 6 1 Prothymosin/parathymosin family Spore_coat_CotO PF14153.1 EGC36632.1 - 0.0045 16.4 9.9 0.0045 16.4 6.9 5.7 4 1 1 5 5 5 2 Spore coat protein CotO BOP1NT PF08145.7 EGC36633.1 - 3e-93 312.3 8.5 3e-93 312.3 5.9 1.8 2 0 0 2 2 2 1 BOP1NT (NUC169) domain WD40 PF00400.27 EGC36633.1 - 1.5e-31 107.1 5.3 2.3e-12 46.2 0.1 7.5 7 1 0 7 7 7 5 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGC36633.1 - 0.0041 15.9 0.3 2 7.1 0.1 2.4 2 0 0 2 2 2 2 Coatomer WD associated region Rav1p_C PF12234.3 EGC36633.1 - 0.58 8.2 4.3 0.13 10.4 0.0 1.9 2 0 0 2 2 2 0 RAVE protein 1 C terminal BUD22 PF09073.5 EGC36633.1 - 4 6.4 31.4 2.6 7.0 20.4 1.7 2 0 0 2 2 2 0 BUD22 La PF05383.12 EGC36634.1 - 1.4e-06 28.0 0.2 3.9e-06 26.5 0.1 1.8 1 0 0 1 1 1 1 La domain RRM_1 PF00076.17 EGC36634.1 - 2.5e-05 23.8 0.1 0.0013 18.3 0.0 2.8 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC36634.1 - 4.7e-05 23.2 0.0 0.017 15.0 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC36634.1 - 0.00042 20.1 0.1 0.036 13.9 0.0 2.7 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC36634.1 - 0.15 11.9 3.2 0.27 11.1 0.0 2.9 3 0 0 3 3 3 0 RNA binding motif GATA PF00320.22 EGC36635.1 - 5.6e-15 54.3 2.8 5.6e-15 54.3 1.9 2.4 2 0 0 2 2 2 1 GATA zinc finger GPCR_chapero_1 PF11904.3 EGC36635.1 - 0.063 12.4 8.3 0.012 14.7 3.1 1.6 2 0 0 2 2 2 0 GPCR-chaperone PAT1 PF09770.4 EGC36635.1 - 0.1 10.8 15.2 0.11 10.6 10.6 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ANAPC15 PF15243.1 EGC36635.1 - 0.49 10.4 4.5 0.081 12.9 0.5 1.6 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 15 YfhO PF09586.5 EGC36635.1 - 6.3 4.6 7.9 7.5 4.4 5.5 1.1 1 0 0 1 1 1 0 Bacterial membrane protein YfhO Nuc-transf PF10127.4 EGC36636.1 - 1.6e-20 73.5 0.1 2.6e-12 46.6 0.0 3.6 3 2 0 3 3 3 3 Predicted nucleotidyltransferase 6PF2K PF01591.13 EGC36637.1 - 2.1e-68 229.7 0.1 2.7e-68 229.3 0.1 1.1 1 0 0 1 1 1 1 6-phosphofructo-2-kinase His_Phos_1 PF00300.17 EGC36637.1 - 6.6e-23 81.5 0.3 5.8e-22 78.4 0.0 2.1 2 0 0 2 2 2 1 Histidine phosphatase superfamily (branch 1) AAA_33 PF13671.1 EGC36637.1 - 1.3e-06 28.3 0.0 2.9e-06 27.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC36637.1 - 0.00011 23.0 0.0 0.00095 19.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC36637.1 - 0.0045 16.1 0.1 0.013 14.5 0.0 1.7 2 0 0 2 2 2 1 Zeta toxin KTI12 PF08433.5 EGC36637.1 - 0.034 13.3 0.0 0.065 12.4 0.0 1.5 1 1 0 1 1 1 0 Chromatin associated protein KTI12 His_Phos_2 PF00328.17 EGC36637.1 - 0.052 12.8 0.3 0.19 11.0 0.0 1.7 1 1 1 2 2 2 0 Histidine phosphatase superfamily (branch 2) POX PF07526.6 EGC36638.1 - 0.36 11.0 10.6 0.27 11.4 1.2 2.5 2 0 0 2 2 2 0 Associated with HOX DGCR6 PF07324.6 EGC36640.1 - 9.7e-09 34.9 8.5 9.7e-09 34.9 5.9 2.8 3 0 0 3 3 3 1 DiGeorge syndrome critical region 6 (DGCR6) protein DUF2458 PF10454.4 EGC36640.1 - 0.0088 15.9 14.4 0.0088 15.9 10.0 3.8 3 2 1 4 4 4 1 Protein of unknown function (DUF2458) Bot1p PF12298.3 EGC36641.1 - 0.00012 22.1 0.0 0.00034 20.6 0.0 1.8 1 0 0 1 1 1 1 Eukaryotic mitochondrial regulator protein MRP-L20 PF12824.2 EGC36641.1 - 0.0022 17.9 0.9 0.0044 17.0 0.0 1.9 2 1 0 2 2 2 1 Mitochondrial ribosomal protein subunit L20 DUF1073 PF06381.6 EGC36641.1 - 0.0053 15.2 0.2 0.035 12.5 0.0 2.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1073) FTHFS PF01268.14 EGC36642.1 - 3.3e-266 883.6 0.2 3.8e-266 883.4 0.1 1.0 1 0 0 1 1 1 1 Formate--tetrahydrofolate ligase Thymidylate_kin PF02223.12 EGC36643.1 - 2.2e-41 141.2 0.0 2.6e-41 141.0 0.0 1.0 1 0 0 1 1 1 1 Thymidylate kinase AAA_28 PF13521.1 EGC36643.1 - 4.1e-05 23.6 0.0 6.2e-05 23.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain PPK2 PF03976.9 EGC36643.1 - 0.055 12.7 0.0 0.13 11.4 0.0 1.6 2 0 0 2 2 2 0 Polyphosphate kinase 2 (PPK2) Rad60-SLD PF11976.3 EGC36643.1 - 0.077 12.6 0.3 12 5.6 0.0 3.0 3 1 0 3 3 3 0 Ubiquitin-2 like Rad60 SUMO-like AAA_16 PF13191.1 EGC36643.1 - 0.083 12.8 0.0 0.12 12.3 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_35 PF14516.1 EGC36643.1 - 0.092 11.3 0.4 0.23 10.0 0.0 1.7 2 0 0 2 2 2 0 AAA-like domain RNA_helicase PF00910.17 EGC36643.1 - 0.11 12.7 0.0 0.2 11.8 0.0 1.5 1 0 0 1 1 1 0 RNA helicase UDPGP PF01704.13 EGC36644.1 - 9.4e-53 179.2 0.0 1.3e-52 178.7 0.0 1.1 1 0 0 1 1 1 1 UTP--glucose-1-phosphate uridylyltransferase NTP_transf_3 PF12804.2 EGC36644.1 - 0.038 14.0 0.0 0.07 13.2 0.0 1.4 1 0 0 1 1 1 0 MobA-like NTP transferase domain FNIP PF05725.7 EGC36646.1 - 1.1e-45 153.2 15.4 2.4e-10 40.2 0.4 7.3 5 1 4 9 9 9 8 FNIP Repeat DUF373 PF04123.8 EGC36648.1 - 0.0019 17.3 3.6 0.0024 16.9 2.5 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF373) UPF0104 PF03706.8 EGC36648.1 - 0.33 10.1 12.4 0.5 9.6 8.6 1.2 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0104) FNIP PF05725.7 EGC36649.1 - 5.6e-38 128.6 72.0 0.00024 20.9 0.1 12.8 6 2 1 12 12 12 11 FNIP Repeat Chromosome_seg PF13889.1 EGC36649.1 - 0.0036 17.1 0.5 1.2e+02 2.6 0.0 4.8 5 0 0 5 5 5 0 Chromosome segregation during meiosis zf-B_box PF00643.19 EGC36649.1 - 0.0045 16.8 1.1 0.0087 15.9 0.8 1.5 1 0 0 1 1 1 1 B-box zinc finger bZIP_C PF12498.3 EGC36649.1 - 1.5 10.1 4.1 1.2 10.3 1.6 1.7 1 1 0 1 1 1 0 Basic leucine-zipper C terminal UCH PF00443.24 EGC36650.1 - 7.1e-51 172.8 13.6 7.1e-51 172.8 9.5 2.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC36650.1 - 7e-26 91.3 24.9 7e-26 91.3 17.3 3.4 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGC36650.1 - 4.6e-05 23.7 4.3 4.6e-05 23.7 3.0 7.7 6 3 0 6 6 6 3 DUSP domain GFA PF04828.9 EGC36650.1 - 0.12 12.3 6.5 0.23 11.4 2.4 2.5 2 0 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme Profilin PF00235.14 EGC36651.1 - 0.00019 21.5 0.0 0.00029 20.9 0.0 1.3 1 0 0 1 1 1 1 Profilin Dimer_Tnp_hAT PF05699.9 EGC36652.1 - 3.3e-12 45.8 0.5 3.3e-12 45.8 0.3 1.7 2 0 0 2 2 2 1 hAT family C-terminal dimerisation region CDC37_C PF08564.5 EGC36652.1 - 0.00033 20.4 0.8 0.00054 19.7 0.6 1.3 1 0 0 1 1 1 1 Cdc37 C terminal domain DUF3043 PF11241.3 EGC36652.1 - 0.09 12.3 0.0 0.13 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) Peptidase_S49_N PF08496.5 EGC36652.1 - 0.48 10.2 3.1 0.84 9.4 2.1 1.4 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Exonuc_VII_L PF02601.10 EGC36652.1 - 0.89 8.6 5.6 1.2 8.2 3.9 1.1 1 0 0 1 1 1 0 Exonuclease VII, large subunit FNIP PF05725.7 EGC36653.1 - 2.1e-23 81.9 23.5 5.9e-07 29.3 1.8 5.9 2 1 4 7 7 7 7 FNIP Repeat Glyco_hydro_114 PF03537.8 EGC36653.1 - 0.0028 17.3 0.1 0.72 9.6 0.0 2.8 1 1 2 3 3 3 2 Glycoside-hydrolase family GH114 Pro_isomerase PF00160.16 EGC36653.1 - 0.062 13.5 0.0 32 4.7 0.0 2.9 3 0 0 3 3 3 0 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Thaumatin PF00314.12 EGC36653.1 - 0.07 12.5 0.0 48 3.3 0.0 3.5 1 1 2 4 4 4 0 Thaumatin family FNIP PF05725.7 EGC36654.1 - 0.16 11.9 54.2 0.063 13.2 0.8 10.4 7 4 1 8 8 8 0 FNIP Repeat Terpene_synth_C PF03936.11 EGC36655.1 - 1.6e-07 30.8 0.2 4e-07 29.5 0.1 1.5 1 1 0 1 1 1 1 Terpene synthase family, metal binding domain DUF310 PF03750.8 EGC36655.1 - 0.064 13.4 0.0 0.15 12.2 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF310) PUF PF00806.14 EGC36656.1 - 5e-20 69.7 5.4 0.00075 18.8 0.0 8.1 8 0 0 8 8 8 5 Pumilio-family RNA binding repeat UCH PF00443.24 EGC36657.1 - 6.1e-57 192.7 37.1 2.3e-55 187.5 25.7 2.0 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC36657.1 - 1.4e-20 73.9 15.1 2.1e-16 60.2 5.7 3.3 3 0 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase DUF506 PF04720.7 EGC36657.1 - 7.7 6.0 15.4 4.5 6.8 3.7 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF506) MEA1 PF06910.6 EGC36658.1 - 0.27 10.8 12.3 0.11 12.2 4.0 2.3 2 0 0 2 2 2 0 Male enhanced antigen 1 (MEA1) BSP_II PF05432.6 EGC36658.1 - 1.2 8.3 27.3 2.1 7.5 10.1 2.2 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) NUDIX PF00293.23 EGC36659.1 - 1.6e-22 79.5 0.0 2.1e-22 79.2 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain DUF1735 PF08522.5 EGC36659.1 - 0.025 14.9 0.1 0.11 12.9 0.0 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF1735) GTA_TIM PF13547.1 EGC36659.1 - 0.053 12.5 0.7 0.077 11.9 0.5 1.2 1 0 0 1 1 1 0 GTA TIM-barrel-like domain FNIP PF05725.7 EGC36660.1 - 1.2e-51 172.4 84.1 7e-06 25.8 0.7 16.9 4 2 13 20 20 20 18 FNIP Repeat zf-B_box PF00643.19 EGC36660.1 - 0.0011 18.7 4.4 0.002 17.9 3.1 1.4 1 0 0 1 1 1 1 B-box zinc finger DUF2523 PF10734.4 EGC36660.1 - 0.08 13.1 0.0 1.5e+02 2.6 0.0 5.6 9 0 0 9 9 9 0 Protein of unknown function (DUF2523) FNIP PF05725.7 EGC36661.1 - 5e-29 99.9 53.8 9.9e-05 22.2 0.0 11.6 4 2 7 14 14 14 12 FNIP Repeat zf-B_box PF00643.19 EGC36661.1 - 0.0008 19.2 4.4 0.0014 18.4 3.1 1.4 1 0 0 1 1 1 1 B-box zinc finger FANCL_C PF11793.3 EGC36662.1 - 0.049 13.6 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 FANCL C-terminal domain CRAL_TRIO PF00650.15 EGC36662.1 - 0.066 12.7 0.2 0.85 9.0 0.0 2.1 2 0 0 2 2 2 0 CRAL/TRIO domain DUF2387 PF09526.5 EGC36662.1 - 1.1 9.2 3.6 3.3 7.7 0.2 2.6 1 1 1 2 2 2 0 Probable metal-binding protein (DUF2387) Glyco_hydro_18 PF00704.23 EGC36663.1 - 1.7e-22 80.3 0.7 2.4e-22 79.8 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Pkinase PF00069.20 EGC36664.1 - 4.4e-72 242.3 0.1 1.6e-71 240.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36664.1 - 2.5e-52 177.5 0.0 4.5e-52 176.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC36664.1 - 0.0095 14.9 0.0 0.025 13.5 0.0 1.6 2 0 0 2 2 2 1 Kinase-like Acyl-CoA_dh_1 PF00441.19 EGC36665.1 - 1.7e-27 96.3 0.1 2.7e-27 95.7 0.1 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGC36665.1 - 1.1e-19 69.6 0.1 1.8e-19 68.9 0.1 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_N PF02771.11 EGC36665.1 - 2.7e-15 56.9 0.0 4.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGC36665.1 - 5.9e-10 39.5 0.0 9.8e-10 38.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain DUF4064 PF13273.1 EGC36665.1 - 0.096 12.7 0.5 0.32 11.1 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4064) Brr6_like_C_C PF10104.4 EGC36666.1 - 2.9e-23 81.8 0.5 2.9e-23 81.8 0.3 1.6 2 0 0 2 2 2 1 Di-sulfide bridge nucleocytoplasmic transport domain FNIP PF05725.7 EGC36667.1 - 8.6e-22 76.8 25.5 5.7e-09 35.7 0.3 7.4 4 2 5 10 10 10 6 FNIP Repeat zf-B_box PF00643.19 EGC36667.1 - 1.1e-06 28.4 3.8 2.1e-06 27.5 2.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC36667.1 - 0.049 13.3 2.7 0.095 12.4 1.9 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) ZZ PF00569.12 EGC36667.1 - 0.077 12.5 6.2 0.16 11.5 4.3 1.5 1 0 0 1 1 1 0 Zinc finger, ZZ type Glyco_hydro_114 PF03537.8 EGC36667.1 - 0.08 12.7 0.1 9.4 6.1 0.0 2.6 1 1 1 2 2 2 0 Glycoside-hydrolase family GH114 Mito_carr PF00153.22 EGC36668.1 - 4.9e-25 87.0 0.1 7.7e-12 44.7 0.0 2.1 1 1 1 2 2 2 2 Mitochondrial carrier protein Pkinase PF00069.20 EGC36669.1 - 1.2e-67 227.8 0.0 2.3e-67 226.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36669.1 - 7.7e-53 179.1 0.0 1.3e-52 178.4 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC36669.1 - 9.9e-05 21.4 0.0 0.00019 20.4 0.0 1.4 1 0 0 1 1 1 1 Kinase-like Nucleoplasmin PF03066.10 EGC36669.1 - 0.66 9.4 23.0 1.6 8.2 9.1 2.6 2 0 0 2 2 2 0 Nucleoplasmin Phage_glycop_gL PF11108.3 EGC36670.1 - 3.4 7.6 8.2 0.096 12.6 0.3 2.4 3 0 0 3 3 3 0 Viral glycoprotein L Glucokinase PF02685.11 EGC36671.1 - 1.2e-23 83.4 0.0 1.5e-23 83.0 0.0 1.1 1 0 0 1 1 1 1 Glucokinase BcrAD_BadFG PF01869.15 EGC36671.1 - 0.17 11.1 0.0 0.42 9.8 0.0 1.4 1 1 0 1 1 1 0 BadF/BadG/BcrA/BcrD ATPase family AAA PF00004.24 EGC36672.1 - 5.5e-52 175.4 0.7 4.3e-42 143.4 0.0 3.9 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) Bromodomain PF00439.20 EGC36672.1 - 2.2e-14 53.1 1.0 1.1e-13 50.9 0.7 2.3 1 0 0 1 1 1 1 Bromodomain AAA_22 PF13401.1 EGC36672.1 - 9.4e-07 29.0 0.5 0.00041 20.4 0.1 4.1 2 2 0 2 2 2 1 AAA domain IstB_IS21 PF01695.12 EGC36672.1 - 3.2e-06 26.6 0.0 2.6e-05 23.7 0.0 2.6 3 0 0 3 3 3 1 IstB-like ATP binding protein AAA_16 PF13191.1 EGC36672.1 - 5.3e-05 23.2 0.0 5.3e-05 23.2 0.0 3.4 5 0 0 5 5 5 1 AAA ATPase domain Sigma54_activ_2 PF14532.1 EGC36672.1 - 0.003 17.5 0.0 0.26 11.3 0.0 3.2 3 0 0 3 3 3 1 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGC36672.1 - 0.031 13.4 0.0 0.11 11.6 0.0 1.9 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGC36672.1 - 0.056 13.1 0.0 0.12 12.1 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_17 PF13207.1 EGC36672.1 - 0.065 14.0 0.0 0.065 14.0 0.0 5.4 4 1 1 5 5 5 0 AAA domain DUF2039 PF10217.4 EGC36673.1 - 7.6e-26 89.9 12.6 7.6e-26 89.9 8.8 2.3 2 0 0 2 2 2 1 Uncharacterized conserved protein (DUF2039) Paired_CXXCH_1 PF09699.5 EGC36673.1 - 0.002 17.6 8.8 0.0038 16.7 0.5 2.8 2 0 0 2 2 2 1 Doubled CXXCH motif (Paired_CXXCH_1) Cytochrome_C7 PF14522.1 EGC36673.1 - 0.0044 16.6 9.2 0.023 14.3 6.4 2.3 1 1 0 1 1 1 1 Cytochrome c7 DZR PF12773.2 EGC36673.1 - 0.42 10.4 10.7 1.1 9.1 4.9 2.4 1 1 0 2 2 2 0 Double zinc ribbon zinc-ribbons_6 PF07191.7 EGC36673.1 - 2.2 8.1 11.3 6.4 6.6 5.4 2.3 1 1 1 2 2 2 0 zinc-ribbons ADK_lid PF05191.9 EGC36673.1 - 2.3 7.9 10.7 1 9.0 0.3 3.4 2 1 1 3 3 3 0 Adenylate kinase, active site lid Ribosomal_L17 PF01196.14 EGC36674.1 - 3.2e-33 114.1 2.8 4.6e-33 113.6 1.9 1.2 1 0 0 1 1 1 1 Ribosomal protein L17 SET PF00856.23 EGC36675.1 - 2.9e-10 40.7 2.5 1.8e-09 38.1 0.0 3.3 3 1 0 3 3 3 1 SET domain Rubis-subs-bind PF09273.6 EGC36675.1 - 1.1e-07 31.8 9.8 5.4e-07 29.5 0.3 3.4 3 0 0 3 3 3 2 Rubisco LSMT substrate-binding CytochromB561_N PF09786.4 EGC36676.1 - 9.5e-14 50.7 2.9 9.5e-14 50.7 2.0 3.0 3 0 0 3 3 3 1 Cytochrome B561, N terminal DUF445 PF04286.7 EGC36677.1 - 0.0043 16.6 14.5 0.0043 16.6 10.0 3.4 2 1 1 3 3 3 1 Protein of unknown function (DUF445) DUF2621 PF11084.3 EGC36677.1 - 0.0095 15.6 2.0 0.029 14.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF2621) ABC_tran PF00005.22 EGC36678.1 - 1.3e-27 96.8 0.0 2e-27 96.1 0.0 1.2 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC36678.1 - 1.9e-09 37.9 1.7 2.5e-07 30.9 1.2 2.2 1 1 0 1 1 1 1 AAA domain SbcCD_C PF13558.1 EGC36678.1 - 0.00038 20.2 0.3 0.0041 16.9 0.2 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA_16 PF13191.1 EGC36678.1 - 0.00074 19.5 0.2 0.0011 18.9 0.2 1.5 1 1 0 1 1 1 1 AAA ATPase domain AAA_15 PF13175.1 EGC36678.1 - 0.0055 15.8 0.1 2.5 7.0 0.0 2.1 2 0 0 2 2 2 2 AAA ATPase domain DUF258 PF03193.11 EGC36678.1 - 0.0062 15.7 0.0 0.0097 15.0 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Rad17 PF03215.10 EGC36678.1 - 0.0096 14.6 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Rad17 cell cycle checkpoint protein SMC_N PF02463.14 EGC36678.1 - 0.01 15.0 0.1 0.26 10.5 0.0 2.1 2 0 0 2 2 2 0 RecF/RecN/SMC N terminal domain NACHT PF05729.7 EGC36678.1 - 0.014 15.0 0.7 1.2 8.8 0.1 2.3 2 0 0 2 2 2 0 NACHT domain AAA_10 PF12846.2 EGC36678.1 - 0.053 12.9 0.2 0.27 10.6 0.1 2.1 1 1 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EGC36678.1 - 0.11 11.9 0.0 0.26 10.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_17 PF13207.1 EGC36678.1 - 0.23 12.3 1.3 1.6 9.5 0.1 2.4 2 1 0 2 2 2 0 AAA domain HCNGP PF07818.8 EGC36679.1 - 2.5e-27 94.7 0.4 2.5e-27 94.7 0.3 2.7 2 1 0 2 2 2 1 HCNGP-like protein ETRAMP PF09716.5 EGC36679.1 - 0.08 12.8 1.0 0.22 11.5 0.7 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2783 PF10932.3 EGC36679.1 - 0.095 12.1 0.1 0.24 10.9 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF2783) Stn1 PF10451.4 EGC36679.1 - 0.33 9.7 6.3 0.61 8.8 4.3 1.4 1 0 0 1 1 1 0 Telomere regulation protein Stn1 DUF2422 PF10337.4 EGC36679.1 - 8.3 5.0 8.1 1.3 7.7 2.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2422) zf-TRAF PF02176.13 EGC36681.1 - 4e-11 43.1 20.0 1.7e-10 41.1 3.1 4.3 2 2 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.11 EGC36681.1 - 0.025 14.2 1.1 0.025 14.2 0.7 3.9 2 1 2 4 4 4 0 Seven in absentia protein family zf-C3HC4_3 PF13920.1 EGC36681.1 - 1.9 8.2 23.6 0.038 13.6 7.9 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36681.1 - 4.1 7.5 31.2 0.084 12.9 11.2 3.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Attachment_P66 PF11263.3 EGC36682.1 - 0.0097 14.9 0.2 0.021 13.8 0.1 1.6 1 0 0 1 1 1 1 Borrelia burgdorferi attachment protein P66 Beach PF02138.13 EGC36683.1 - 2.7e-58 197.5 3.8 3.2e-58 197.2 0.0 3.0 1 1 1 2 2 2 1 Beige/BEACH domain WD40 PF00400.27 EGC36683.1 - 1.5e-13 50.0 6.3 3.7e-07 29.7 0.0 5.7 5 0 0 5 5 5 2 WD domain, G-beta repeat Pkinase PF00069.20 EGC36683.1 - 1.8e-12 46.9 0.6 1.1e-05 24.6 0.0 2.7 2 0 0 2 2 2 2 Protein kinase domain Kinase-like PF14531.1 EGC36683.1 - 0.00023 20.1 0.0 0.00046 19.2 0.0 1.4 1 0 0 1 1 1 1 Kinase-like DUF3053 PF11254.3 EGC36684.1 - 0.019 14.2 0.0 0.023 13.9 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) DUF3053 PF11254.3 EGC36685.1 - 0.15 11.3 0.0 0.19 10.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3053) EF-hand_1 PF00036.27 EGC36686.1 - 1.7e-12 45.6 4.6 0.0039 16.3 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_6 PF13405.1 EGC36686.1 - 2.3e-11 42.5 1.2 0.0029 17.3 0.0 3.7 4 0 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EGC36686.1 - 5.1e-11 42.5 2.3 2e-06 27.8 0.3 2.6 2 1 0 2 2 2 2 EF-hand domain pair EF-hand_8 PF13833.1 EGC36686.1 - 1.8e-05 24.2 0.1 0.24 11.0 0.0 3.4 3 0 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC36686.1 - 2.1e-05 23.6 0.1 0.84 9.0 0.0 3.5 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EGC36686.1 - 0.0013 18.7 4.9 0.37 10.8 1.0 2.9 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_10 PF14788.1 EGC36686.1 - 0.02 14.5 1.1 3.2 7.4 0.1 2.5 2 0 0 2 2 2 0 EF hand PTS-HPr PF00381.14 EGC36687.1 - 5.6e-16 58.2 0.1 5.9e-16 58.1 0.1 1.0 1 0 0 1 1 1 1 PTS HPr component phosphorylation site VHL PF01847.11 EGC36689.1 - 0.049 13.1 0.1 0.24 10.9 0.0 2.1 2 0 0 2 2 2 0 von Hippel-Lindau disease tumour suppressor protein DUF4172 PF13776.1 EGC36689.1 - 0.095 12.8 0.2 0.25 11.4 0.1 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF4172) Ubie_methyltran PF01209.13 EGC36691.1 - 3.1e-22 78.8 0.2 2.6e-20 72.5 0.2 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGC36691.1 - 2.8e-19 69.1 1.1 4.7e-19 68.4 0.1 1.8 2 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36691.1 - 3.7e-16 59.3 0.0 6.2e-16 58.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36691.1 - 3.1e-12 47.0 0.0 5.3e-12 46.3 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36691.1 - 5e-12 45.8 0.0 7.4e-12 45.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36691.1 - 7.1e-11 42.4 0.1 1.6e-10 41.3 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC36691.1 - 1.2e-08 35.1 0.0 2.3e-08 34.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain DUF938 PF06080.7 EGC36691.1 - 0.00029 20.4 0.0 0.00066 19.2 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF938) MTS PF05175.9 EGC36691.1 - 0.00081 18.8 0.1 0.0022 17.3 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC36691.1 - 0.0014 18.6 0.0 0.0044 17.0 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGC36691.1 - 0.0016 17.6 0.0 0.0026 16.9 0.0 1.3 1 0 0 1 1 1 1 Tellurite resistance protein TehB PCMT PF01135.14 EGC36691.1 - 0.0017 17.9 0.0 0.004 16.7 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) PrmA PF06325.8 EGC36691.1 - 0.0038 16.3 0.3 0.033 13.3 0.0 2.0 2 0 0 2 2 2 1 Ribosomal protein L11 methyltransferase (PrmA) PA28_alpha PF02251.13 EGC36691.1 - 0.0075 16.4 0.1 0.05 13.7 0.0 2.5 2 0 0 2 2 2 1 Proteasome activator pa28 alpha subunit Methyltransf_4 PF02390.12 EGC36691.1 - 0.011 14.7 0.6 0.27 10.2 0.4 2.3 1 1 0 1 1 1 0 Putative methyltransferase DREV PF05219.7 EGC36691.1 - 0.014 14.3 0.0 0.024 13.5 0.0 1.3 1 0 0 1 1 1 0 DREV methyltransferase FmrO PF07091.6 EGC36691.1 - 0.039 12.9 0.0 0.064 12.2 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Leukocidin PF07968.7 EGC36691.1 - 0.056 13.0 0.8 0.1 12.2 0.0 1.7 2 0 0 2 2 2 0 Leukocidin/Hemolysin toxin family Methyltransf_8 PF05148.10 EGC36691.1 - 0.11 12.1 0.2 4 7.0 0.0 2.5 1 1 0 2 2 2 0 Hypothetical methyltransferase Methyltransf_20 PF12147.3 EGC36691.1 - 0.12 11.2 0.0 0.2 10.4 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase Ubie_methyltran PF01209.13 EGC36692.1 - 5.8e-21 74.6 0.4 3.6e-19 68.7 0.3 2.1 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_31 PF13847.1 EGC36692.1 - 1e-19 70.5 0.4 5.3e-19 68.2 0.0 1.9 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36692.1 - 1.9e-16 60.2 0.0 3.4e-16 59.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36692.1 - 8.7e-13 48.8 0.0 2e-12 47.6 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36692.1 - 1.6e-11 44.1 0.0 2.4e-11 43.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36692.1 - 5.3e-11 42.8 0.1 1.2e-10 41.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC36692.1 - 6e-09 36.1 0.0 1.4e-08 35.0 0.0 1.6 2 0 0 2 2 2 1 Methyltransferase domain DUF938 PF06080.7 EGC36692.1 - 0.00021 20.8 0.0 0.00035 20.1 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF938) TehB PF03848.9 EGC36692.1 - 0.00066 18.8 0.0 0.001 18.3 0.0 1.2 1 0 0 1 1 1 1 Tellurite resistance protein TehB MTS PF05175.9 EGC36692.1 - 0.00075 18.9 0.0 0.0015 17.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC36692.1 - 0.00082 19.3 0.0 0.0023 17.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC36692.1 - 0.0016 18.0 0.0 0.0027 17.2 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) DREV PF05219.7 EGC36692.1 - 0.006 15.4 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 DREV methyltransferase PrmA PF06325.8 EGC36692.1 - 0.011 14.9 0.0 0.02 14.0 0.0 1.4 1 0 0 1 1 1 0 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGC36692.1 - 0.013 14.5 0.2 0.083 11.9 0.1 2.2 1 1 0 1 1 1 0 Putative methyltransferase PA28_alpha PF02251.13 EGC36692.1 - 0.031 14.4 0.1 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit FmrO PF07091.6 EGC36692.1 - 0.034 13.1 0.0 0.061 12.3 0.0 1.3 1 0 0 1 1 1 0 Ribosomal RNA methyltransferase (FmrO) Leukocidin PF07968.7 EGC36692.1 - 0.042 13.4 0.1 0.073 12.7 0.0 1.3 1 0 0 1 1 1 0 Leukocidin/Hemolysin toxin family Methyltransf_20 PF12147.3 EGC36692.1 - 0.05 12.4 0.0 0.076 11.8 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase Methyltransf_16 PF10294.4 EGC36692.1 - 0.13 11.7 0.0 0.2 11.1 0.0 1.2 1 0 0 1 1 1 0 Putative methyltransferase NST1 PF13945.1 EGC36693.1 - 8.8e-42 143.3 11.7 8.8e-42 143.3 8.1 10.4 4 3 7 11 11 11 2 Salt tolerance down-regulator Aminotran_3 PF00202.16 EGC36694.1 - 2.6e-92 309.2 0.0 3.2e-92 308.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-III Pkinase PF00069.20 EGC36695.1 - 7.5e-59 198.9 0.0 9.8e-59 198.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36695.1 - 1.4e-37 129.2 0.0 1.8e-37 128.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC36695.1 - 7.8e-10 38.1 0.0 1.2e-09 37.5 0.0 1.4 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC36695.1 - 0.043 13.5 0.0 1.1 8.8 0.0 2.2 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kdo PF06293.9 EGC36695.1 - 0.17 10.9 0.0 0.25 10.3 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MitMem_reg PF13012.1 EGC36696.1 - 4.8e-33 113.6 3.0 1.1e-32 112.4 2.1 1.7 1 0 0 1 1 1 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGC36696.1 - 1e-26 92.9 0.0 3.4e-26 91.2 0.0 1.9 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease DUF2999 PF11212.3 EGC36696.1 - 0.02 14.8 0.0 0.068 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2999) ABC_tran PF00005.22 EGC36698.1 - 3.2e-31 108.4 0.0 3.2e-31 108.4 0.0 2.4 2 1 0 2 2 2 1 ABC transporter SbcCD_C PF13558.1 EGC36698.1 - 0.0059 16.4 1.5 0.062 13.2 0.1 2.9 2 1 0 2 2 2 1 Putative exonuclease SbcCD, C subunit DUF258 PF03193.11 EGC36698.1 - 0.068 12.3 0.7 0.12 11.5 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGC36698.1 - 0.18 12.6 1.3 0.43 11.3 0.4 2.0 2 0 0 2 2 2 0 AAA domain UPF0697 PF15117.1 EGC36698.1 - 0.21 11.3 0.1 0.21 11.3 0.1 2.5 1 1 1 2 2 2 0 Uncharacterised protein family UPF0697 AAA_28 PF13521.1 EGC36698.1 - 0.24 11.3 0.8 1.1 9.2 0.6 2.0 2 0 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGC36698.1 - 0.28 10.5 1.2 0.73 9.1 0.1 2.0 2 1 0 2 2 2 0 AAA domain Nop PF01798.13 EGC36701.1 - 7.2e-56 187.6 0.5 1.9e-55 186.3 0.4 1.7 1 0 0 1 1 1 1 Putative snoRNA binding domain NOSIC PF08060.8 EGC36701.1 - 1.1e-26 92.3 0.0 2.3e-26 91.3 0.0 1.6 1 0 0 1 1 1 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGC36701.1 - 6.8e-21 74.1 0.9 6.8e-21 74.1 0.6 3.9 2 1 0 2 2 2 1 NOP5NT (NUC127) domain CDC27 PF09507.5 EGC36701.1 - 0.49 9.5 63.3 0.65 9.1 43.9 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 tRNA-synt_2 PF00152.15 EGC36702.1 - 8.3e-82 274.6 0.1 1.1e-81 274.2 0.1 1.1 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA_anti-codon PF01336.20 EGC36702.1 - 1.2e-09 37.8 1.4 1.9e-09 37.2 0.2 1.9 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGC36702.1 - 0.0096 15.1 0.1 0.54 9.4 0.0 3.0 3 0 0 3 3 3 1 tRNA synthetases class II core domain (F) tRNA-synt_2b PF00587.20 EGC36702.1 - 0.01 15.4 0.0 0.35 10.4 0.0 2.3 1 1 0 1 1 1 0 tRNA synthetase class II core domain (G, H, P, S and T) WH2 PF02205.15 EGC36704.1 - 3.6e-11 42.2 1.2 3.6e-11 42.2 0.8 2.3 2 0 0 2 2 2 1 WH2 motif SH3_1 PF00018.23 EGC36704.1 - 8.4e-08 31.4 0.0 1.5e-07 30.6 0.0 1.4 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC36704.1 - 6.2e-05 22.5 0.5 0.00011 21.6 0.1 1.7 2 0 0 2 2 2 1 Variant SH3 domain HR1 PF02185.11 EGC36704.1 - 0.025 14.3 0.3 0.043 13.5 0.2 1.3 1 0 0 1 1 1 0 Hr1 repeat DMPK_coil PF08826.5 EGC36704.1 - 0.05 13.4 1.9 0.086 12.7 1.3 1.3 1 0 0 1 1 1 0 DMPK coiled coil domain like IncA PF04156.9 EGC36704.1 - 0.13 11.8 0.1 0.19 11.2 0.1 1.1 1 0 0 1 1 1 0 IncA protein SH3_2 PF07653.12 EGC36704.1 - 0.16 11.4 0.0 0.28 10.7 0.0 1.3 1 0 0 1 1 1 0 Variant SH3 domain DUF4140 PF13600.1 EGC36704.1 - 0.3 11.5 1.4 0.57 10.6 1.0 1.3 1 0 0 1 1 1 0 N-terminal domain of unknown function (DUF4140) Mak16 PF04874.9 EGC36706.1 - 3.5 7.7 10.0 0.94 9.6 3.9 2.2 1 1 1 2 2 2 0 Mak16 protein C-terminal region Bromodomain PF00439.20 EGC36707.1 - 3.3e-08 33.3 0.3 3.3e-08 33.3 0.2 2.6 3 0 0 3 3 3 1 Bromodomain FHA PF00498.21 EGC36707.1 - 0.0022 18.0 0.0 0.005 16.9 0.0 1.7 1 0 0 1 1 1 1 FHA domain Tetraspannin PF00335.15 EGC36708.1 - 0.011 15.0 1.8 0.013 14.8 1.2 1.1 1 0 0 1 1 1 0 Tetraspanin family Ureide_permease PF07168.6 EGC36708.1 - 0.019 13.6 0.5 0.019 13.6 0.3 1.8 1 1 1 2 2 2 0 Ureide permease Spore_III_AF PF09581.5 EGC36708.1 - 0.033 14.0 0.4 0.033 14.0 0.3 2.0 1 1 1 2 2 2 0 Stage III sporulation protein AF (Spore_III_AF) DUF4407 PF14362.1 EGC36708.1 - 0.13 11.1 2.4 0.2 10.5 1.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) DUF95 PF01944.12 EGC36708.1 - 0.17 11.5 0.2 0.25 10.9 0.0 1.4 1 1 0 1 1 1 0 Integral membrane protein DUF95 Brr6_like_C_C PF10104.4 EGC36708.1 - 0.25 10.8 2.2 0.17 11.3 0.4 1.7 1 1 1 2 2 2 0 Di-sulfide bridge nucleocytoplasmic transport domain DUF87 PF01935.12 EGC36708.1 - 3.6 7.3 10.2 5.9 6.6 7.0 1.4 1 1 0 1 1 1 0 Domain of unknown function DUF87 PAPS_reduct PF01507.14 EGC36709.1 - 3.7e-30 105.0 0.0 4.2e-20 72.2 0.0 2.2 1 1 1 2 2 2 2 Phosphoadenosine phosphosulfate reductase family Plant_vir_prot PF01307.12 EGC36709.1 - 0.00013 21.6 0.2 0.00034 20.2 0.1 1.7 1 0 0 1 1 1 1 Plant viral movement protein AAA PF00004.24 EGC36710.1 - 4.6e-15 55.9 0.1 1.2e-14 54.6 0.0 1.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC36710.1 - 3.3e-10 40.2 0.0 8.5e-10 38.8 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC36710.1 - 4e-08 33.4 0.0 2.2e-07 31.0 0.0 2.2 1 1 0 1 1 1 1 AAA ATPase domain Arch_ATPase PF01637.13 EGC36710.1 - 7.4e-06 25.8 0.1 2.7e-05 24.0 0.1 1.9 1 0 0 1 1 1 1 Archaeal ATPase NACHT PF05729.7 EGC36710.1 - 3.4e-05 23.5 0.0 7.3e-05 22.4 0.0 1.5 1 0 0 1 1 1 1 NACHT domain DUF2075 PF09848.4 EGC36710.1 - 0.00069 18.6 0.0 0.0012 17.8 0.0 1.3 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) NB-ARC PF00931.17 EGC36710.1 - 0.0036 16.2 0.0 0.0065 15.3 0.0 1.4 1 0 0 1 1 1 1 NB-ARC domain AAA_19 PF13245.1 EGC36710.1 - 0.0037 16.9 0.1 0.0098 15.6 0.1 1.6 1 0 0 1 1 1 1 Part of AAA domain AAA_11 PF13086.1 EGC36710.1 - 0.0053 16.3 0.4 0.0053 16.3 0.3 2.4 2 1 0 2 2 1 1 AAA domain AFG1_ATPase PF03969.11 EGC36710.1 - 0.0093 14.8 0.0 0.017 13.9 0.0 1.4 1 1 0 1 1 1 1 AFG1-like ATPase AAA_14 PF13173.1 EGC36710.1 - 0.015 15.2 0.3 0.049 13.5 0.2 1.9 1 1 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC36710.1 - 0.016 15.5 0.0 0.016 15.5 0.0 2.7 2 2 0 2 2 1 0 AAA domain DEAD PF00270.24 EGC36710.1 - 0.026 14.0 0.0 0.5 9.8 0.0 2.3 2 0 0 2 2 2 0 DEAD/DEAH box helicase Viral_helicase1 PF01443.13 EGC36710.1 - 0.041 13.4 0.2 0.12 11.8 0.1 1.9 1 1 0 1 1 1 0 Viral (Superfamily 1) RNA helicase PIF1 PF05970.9 EGC36710.1 - 0.045 12.6 0.1 0.086 11.7 0.0 1.4 1 0 0 1 1 1 0 PIF1-like helicase NTPase_1 PF03266.10 EGC36710.1 - 0.046 13.4 0.4 0.14 11.8 0.2 1.8 2 0 0 2 2 2 0 NTPase RuvB_N PF05496.7 EGC36710.1 - 0.068 12.1 0.1 3.7 6.5 0.0 2.2 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGC36710.1 - 0.092 12.4 0.1 5.7 6.6 0.0 2.4 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGC36710.1 - 0.1 12.0 0.0 0.18 11.2 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain Cdc6_C PF09079.6 EGC36710.1 - 0.11 12.2 0.2 0.69 9.6 0.0 2.2 2 0 0 2 2 2 0 CDC6, C terminal AAA_17 PF13207.1 EGC36710.1 - 0.17 12.7 0.0 0.17 12.7 0.0 2.9 3 1 0 3 3 2 0 AAA domain Pro-kuma_activ PF09286.6 EGC36711.1 - 6e-28 97.6 0.0 1e-27 96.9 0.0 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC36711.1 - 2.7e-05 23.4 0.4 6.9e-05 22.1 0.3 1.8 1 1 0 1 1 1 1 Subtilase family p450 PF00067.17 EGC36713.1 - 9.7e-60 202.3 0.0 1.1e-59 202.1 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Glyco_hydro_9 PF00759.14 EGC36716.1 - 4.2e-71 240.1 6.3 4.8e-71 239.9 4.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Mago-bind PF09282.5 EGC36717.1 - 7.6e-12 44.5 0.1 1.1e-11 44.0 0.0 1.3 1 0 0 1 1 1 1 Mago binding DIOX_N PF14226.1 EGC36718.1 - 1.3e-20 74.0 0.0 2.1e-20 73.3 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC36718.1 - 1e-19 70.6 0.0 1.9e-19 69.7 0.0 1.4 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3045 PF11243.3 EGC36718.1 - 0.042 14.0 0.1 0.14 12.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) FNIP PF05725.7 EGC36719.1 - 2.7e-106 347.2 51.2 1e-16 60.6 1.4 7.9 3 2 6 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.8 EGC36719.1 - 5.6e-06 26.2 0.2 17 5.4 0.0 6.6 1 1 7 8 8 8 1 Phage minor tail protein DUF1769 PF08588.5 EGC36719.1 - 0.0094 15.8 25.3 0.96 9.4 0.4 8.6 2 2 10 12 12 12 3 Protein of unknown function (DUF1769) DUF3215 PF11503.3 EGC36719.1 - 0.028 14.0 0.1 0.39 10.3 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF3215) Terminase_1 PF03354.10 EGC36719.1 - 0.13 10.6 0.0 0.18 10.1 0.0 1.1 1 0 0 1 1 1 0 Phage Terminase LRR_6 PF13516.1 EGC36719.1 - 0.95 9.7 21.2 24 5.3 0.1 9.3 10 1 1 11 11 11 0 Leucine Rich repeat Kelch_3 PF13415.1 EGC36720.1 - 1e-18 66.9 8.1 0.00026 21.0 0.0 6.4 5 1 0 6 6 6 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC36720.1 - 2.7e-15 55.8 14.6 1.3e-05 24.8 0.1 5.6 4 1 1 5 5 5 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC36720.1 - 3e-15 55.7 7.9 0.035 14.0 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EGC36720.1 - 1.9e-13 49.9 15.4 0.00025 21.0 0.1 5.5 6 0 0 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EGC36720.1 - 5e-10 38.7 11.8 0.01 15.3 0.2 5.2 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EGC36720.1 - 1.3e-06 27.8 15.1 0.0028 17.3 0.3 5.6 5 1 0 5 5 5 3 Kelch motif Rax2 PF12768.2 EGC36720.1 - 0.0011 18.2 2.6 0.0042 16.3 0.8 2.1 2 0 0 2 2 2 1 Cortical protein marker for cell polarity Syntaxin_2 PF14523.1 EGC36721.1 - 4.1e-11 42.7 6.8 4.1e-11 42.7 4.7 2.6 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGC36721.1 - 1.5e-06 27.7 9.0 6.2e-06 25.7 4.1 2.9 2 0 0 2 2 2 1 SNARE domain DUF4199 PF13858.1 EGC36721.1 - 0.021 14.7 1.2 0.023 14.6 0.2 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4199) UBN2 PF14223.1 EGC36721.1 - 0.089 12.5 5.8 0.58 9.9 0.3 3.1 3 0 0 3 3 3 0 gag-polypeptide of LTR copia-type Amnionless PF14828.1 EGC36721.1 - 2.2 6.6 12.1 4.7 5.5 7.0 2.0 1 1 1 2 2 2 0 Amnionless Fusion_gly PF00523.13 EGC36721.1 - 3.5 5.5 13.2 0.41 8.6 4.9 2.2 2 1 0 2 2 2 0 Fusion glycoprotein F0 RhoGEF PF00621.15 EGC36722.1 - 6.6e-49 166.2 10.9 2.1e-48 164.5 7.5 2.0 1 0 0 1 1 1 1 RhoGEF domain PH PF00169.24 EGC36722.1 - 4.6e-21 74.9 18.2 1.3e-13 51.0 1.7 4.0 4 0 0 4 4 4 2 PH domain ArfGap PF01412.13 EGC36722.1 - 5.5e-21 74.5 1.2 5.5e-21 74.5 0.8 2.5 2 0 0 2 2 2 1 Putative GTPase activating protein for Arf CH PF00307.26 EGC36722.1 - 6.5e-15 55.1 0.2 3.5e-14 52.7 0.0 2.4 2 0 0 2 2 2 1 Calponin homology (CH) domain PH_11 PF15413.1 EGC36722.1 - 2e-05 24.7 9.0 0.0069 16.6 1.6 4.7 3 2 0 3 3 3 2 Pleckstrin homology domain PH_9 PF15410.1 EGC36722.1 - 2.6e-05 24.3 6.1 0.001 19.2 0.2 3.9 3 1 0 3 3 3 1 Pleckstrin homology domain CAMSAP_CH PF11971.3 EGC36722.1 - 0.00022 20.7 0.4 0.00079 19.0 0.0 2.3 2 0 0 2 2 2 1 CAMSAP CH domain IQ PF00612.22 EGC36722.1 - 0.0077 15.7 5.5 0.086 12.5 0.7 2.7 2 0 0 2 2 2 1 IQ calmodulin-binding motif PH_8 PF15409.1 EGC36722.1 - 0.023 14.7 0.4 0.069 13.2 0.3 1.9 1 0 0 1 1 1 0 Pleckstrin homology domain Mcp5_PH PF12814.2 EGC36722.1 - 0.053 13.4 7.7 0.048 13.5 0.3 3.8 3 0 0 3 3 3 0 Meiotic cell cortex C-terminal pleckstrin homology ATG27 PF09451.5 EGC36723.1 - 3.8e-07 29.6 1.2 0.00011 21.6 0.0 2.1 2 0 0 2 2 2 2 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EGC36723.1 - 0.00052 19.1 0.1 0.00073 18.6 0.0 1.2 1 0 0 1 1 1 1 Mannose-6-phosphate receptor CIMR PF00878.13 EGC36723.1 - 0.003 17.3 0.5 0.0047 16.7 0.3 1.3 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Rab5ip PF07019.7 EGC36724.1 - 2.6e-17 62.7 7.2 3.5e-17 62.3 5.0 1.1 1 0 0 1 1 1 1 Rab5-interacting protein (Rab5ip) ABC2_membrane_3 PF12698.2 EGC36724.1 - 0.0079 15.2 2.1 0.0096 14.9 1.4 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein FA_desaturase PF00487.19 EGC36724.1 - 0.22 10.9 2.6 0.52 9.7 1.7 1.7 1 1 0 1 1 1 0 Fatty acid desaturase FtsJ PF01728.14 EGC36725.1 - 3.1e-29 102.2 0.0 7.7e-29 100.9 0.0 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase G-patch PF01585.18 EGC36725.1 - 2.6e-10 39.9 0.5 6.4e-10 38.6 0.4 1.7 1 0 0 1 1 1 1 G-patch domain G-patch_2 PF12656.2 EGC36725.1 - 2.7e-06 27.1 3.9 3.5e-06 26.7 0.6 2.6 2 0 0 2 2 2 1 DExH-box splicing factor binding site CENP-B_dimeris PF09026.5 EGC36725.1 - 2.7 8.2 12.9 7.3 6.8 8.9 1.7 1 0 0 1 1 1 0 Centromere protein B dimerisation domain LETM1 PF07766.8 EGC36726.1 - 2.8e-19 69.1 0.2 2.8e-19 69.1 0.1 2.1 2 0 0 2 2 2 1 LETM1-like protein CT47 PF15623.1 EGC36726.1 - 0.0081 15.9 11.9 0.009 15.7 8.3 1.1 1 0 0 1 1 1 1 Cancer/testis gene family 47 DUF1957 PF09210.6 EGC36726.1 - 0.049 13.6 0.2 0.1 12.6 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF1957) DDHD PF02862.12 EGC36726.1 - 0.062 13.0 3.9 0.072 12.8 2.7 1.2 1 0 0 1 1 1 0 DDHD domain Ycf1 PF05758.7 EGC36726.1 - 0.1 10.3 6.2 0.083 10.5 4.3 1.1 1 0 0 1 1 1 0 Ycf1 RNase_H2-Ydr279 PF09468.5 EGC36726.1 - 0.34 10.0 15.1 4.4 6.4 10.5 2.1 1 1 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) RtcB PF01139.12 EGC36726.1 - 0.99 8.3 4.1 1.4 7.8 2.8 1.2 1 0 0 1 1 1 0 tRNA-splicing ligase RtcB PA26 PF04636.8 EGC36726.1 - 1.4 7.5 5.3 1.9 7.1 3.7 1.2 1 0 0 1 1 1 0 PA26 p53-induced protein (sestrin) IncA PF04156.9 EGC36726.1 - 1.8 8.0 11.9 2.9 7.4 8.3 1.5 1 0 0 1 1 1 0 IncA protein TRAP_alpha PF03896.11 EGC36726.1 - 2.5 7.0 10.2 3.6 6.5 7.1 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit APG6 PF04111.7 EGC36726.1 - 3 6.8 18.2 4.2 6.3 12.6 1.3 1 0 0 1 1 1 0 Autophagy protein Apg6 Peptidase_C78 PF07910.8 EGC36727.1 - 1.3e-53 181.3 0.2 2.5e-53 180.4 0.2 1.5 1 0 0 1 1 1 1 Peptidase family C78 RP-C_C PF11800.3 EGC36728.1 - 0.005 16.5 0.6 0.0073 16.0 0.4 1.2 1 0 0 1 1 1 1 Replication protein C C-terminal region bZIP_1 PF00170.16 EGC36728.1 - 0.012 15.5 0.4 0.029 14.3 0.3 1.7 1 0 0 1 1 1 0 bZIP transcription factor RNA_polI_A14 PF08203.6 EGC36728.1 - 0.018 15.2 0.7 0.045 13.9 0.5 1.6 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 bZIP_2 PF07716.10 EGC36728.1 - 0.044 13.5 1.8 0.095 12.5 1.2 1.5 1 0 0 1 1 1 0 Basic region leucine zipper Ecm29 PF13001.2 EGC36729.1 - 5e-05 21.9 0.0 5.7e-05 21.7 0.0 1.1 1 0 0 1 1 1 1 Proteasome stabiliser HEAT PF02985.17 EGC36729.1 - 0.0001 22.0 0.3 6.5 7.1 0.0 4.4 4 0 0 4 4 4 1 HEAT repeat HEAT_2 PF13646.1 EGC36729.1 - 0.003 17.8 0.0 0.053 13.7 0.0 2.2 1 1 1 2 2 2 2 HEAT repeats HEAT_EZ PF13513.1 EGC36729.1 - 0.0033 17.8 0.0 11 6.6 0.0 3.4 3 1 1 4 4 4 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC36729.1 - 0.029 14.7 0.0 0.28 11.6 0.0 2.1 2 0 0 2 2 2 0 Vacuolar 14 Fab1-binding region Adaptin_N PF01602.15 EGC36729.1 - 0.037 12.3 0.1 0.058 11.7 0.1 1.6 1 1 0 1 1 1 0 Adaptin N terminal region ParcG PF10274.4 EGC36729.1 - 0.12 12.2 0.0 2 8.3 0.0 2.0 1 1 0 2 2 2 0 Parkin co-regulated protein adh_short PF00106.20 EGC36730.1 - 4.7e-18 65.6 0.0 7.6e-18 64.9 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC36730.1 - 2e-09 37.3 0.0 4.5e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC36730.1 - 0.0003 20.6 0.0 0.00084 19.1 0.0 1.8 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGC36730.1 - 0.00053 19.5 0.0 0.00075 19.0 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Shikimate_DH PF01488.15 EGC36730.1 - 0.018 15.1 0.2 0.075 13.1 0.1 2.0 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase PLDc PF00614.17 EGC36730.1 - 0.097 12.5 1.7 0.13 12.1 0.1 2.1 2 0 0 2 2 2 0 Phospholipase D Active site motif Mnd1 PF03962.10 EGC36731.1 - 1.8e-50 171.2 11.9 2.1e-50 171.0 8.2 1.0 1 0 0 1 1 1 1 Mnd1 family Phage_GP20 PF06810.6 EGC36731.1 - 0.00021 20.7 14.8 0.00041 19.8 10.3 1.5 1 0 0 1 1 1 1 Phage minor structural protein GP20 DUF342 PF03961.8 EGC36731.1 - 0.0023 16.4 7.5 0.0027 16.1 5.2 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF342) S10_plectin PF03501.10 EGC36731.1 - 0.033 14.0 0.2 0.074 12.9 0.1 1.7 1 1 0 1 1 1 0 Plectin/S10 domain Mitofilin PF09731.4 EGC36731.1 - 0.037 12.7 11.9 0.043 12.4 8.3 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Endotoxin_N PF03945.9 EGC36731.1 - 0.048 13.0 3.0 0.069 12.5 2.1 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain APG6 PF04111.7 EGC36731.1 - 0.14 11.1 9.7 0.16 10.9 6.7 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 Uteroglobin PF01099.12 EGC36731.1 - 0.55 10.0 7.4 0.97 9.2 0.5 3.1 3 0 0 3 3 3 0 Uteroglobin family TMP_2 PF06791.8 EGC36731.1 - 0.6 9.6 2.6 0.95 9.0 0.2 2.0 1 1 1 2 2 2 0 Prophage tail length tape measure protein IncA PF04156.9 EGC36731.1 - 1.8 8.1 12.8 1.7 8.2 7.9 1.5 1 1 0 1 1 1 0 IncA protein DivIC PF04977.10 EGC36731.1 - 2.3 7.7 14.5 2.2 7.8 2.7 2.8 1 1 2 3 3 3 0 Septum formation initiator DUF2935 PF11155.3 EGC36731.1 - 2.8 8.0 8.3 7.1 6.7 5.8 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF2935) Ank_2 PF12796.2 EGC36732.1 - 2.7e-09 37.2 0.6 2.8e-05 24.3 0.1 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC36732.1 - 2.4e-07 31.0 1.1 0.0036 17.7 0.1 4.0 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36732.1 - 3.9e-05 23.4 2.4 1.6 9.2 0.1 4.4 5 0 0 5 5 5 1 Ankyrin repeat Ank PF00023.25 EGC36732.1 - 0.0002 21.0 0.1 0.64 9.9 0.0 4.3 4 0 0 4 4 4 1 Ankyrin repeat Peptidase_M16 PF00675.15 EGC36732.1 - 0.0013 18.4 0.0 0.0035 17.1 0.0 1.7 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Ank_5 PF13857.1 EGC36732.1 - 0.071 13.3 0.0 0.071 13.3 0.0 5.3 4 2 2 6 6 6 0 Ankyrin repeats (many copies) IncA PF04156.9 EGC36732.1 - 0.35 10.4 1.5 0.91 9.0 0.1 2.2 2 0 0 2 2 2 0 IncA protein Pheromone PF08015.6 EGC36732.1 - 0.75 10.6 6.8 4.2 8.2 4.7 2.4 1 0 0 1 1 1 0 Fungal mating-type pheromone Ank_2 PF12796.2 EGC36733.1 - 2.9e-18 65.9 0.0 4e-09 36.6 0.0 2.1 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC36733.1 - 1.5e-11 44.5 0.0 3.2e-07 30.6 0.0 2.4 2 0 0 2 2 2 2 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC36733.1 - 3.6e-11 42.9 0.0 0.011 15.9 0.0 3.5 2 2 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36733.1 - 2.2e-08 33.5 0.0 0.0039 17.2 0.0 4.2 4 0 0 4 4 4 2 Ankyrin repeat Ank PF00023.25 EGC36733.1 - 2.2e-06 27.1 0.0 0.00025 20.7 0.0 3.4 4 0 0 4 4 4 1 Ankyrin repeat WD40 PF00400.27 EGC36735.1 - 1.2e-05 24.9 13.7 0.0023 17.7 0.5 5.5 5 0 0 5 5 5 2 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC36735.1 - 0.015 15.0 1.0 0.061 13.1 0.1 2.4 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, middle region RAB3GAP2_N PF14655.1 EGC36735.1 - 0.028 13.4 0.3 0.064 12.2 0.1 1.6 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Ribosomal_L18e PF00828.14 EGC36736.1 - 7e-24 84.6 0.4 1.2e-23 83.9 0.3 1.3 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 Metallophos PF00149.23 EGC36738.1 - 1.6e-12 47.2 4.3 2.5e-11 43.3 2.4 2.6 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC36738.1 - 4e-07 30.0 0.0 7.1e-07 29.1 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain OmpH PF03938.9 EGC36739.1 - 0.0026 17.7 15.2 0.0026 17.7 10.5 4.0 3 1 0 3 3 3 2 Outer membrane protein (OmpH-like) AARP2CN PF08142.7 EGC36739.1 - 0.031 13.8 0.0 5.4 6.6 0.0 3.1 2 0 0 2 2 2 0 AARP2CN (NUC121) domain DCP2 PF05026.8 EGC36740.1 - 7.9e-32 109.0 2.5 7.9e-32 109.0 1.7 1.8 2 0 0 2 2 2 1 Dcp2, box A domain NUDIX PF00293.23 EGC36740.1 - 1.8e-15 56.7 0.0 3.2e-15 55.9 0.0 1.3 1 0 0 1 1 1 1 NUDIX domain Asn_synthase PF00733.16 EGC36742.1 - 9.6e-44 149.7 0.0 1.3e-43 149.3 0.0 1.2 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC36742.1 - 4.4e-24 84.6 0.0 7.7e-24 83.8 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC36742.1 - 1.9e-16 60.2 0.0 3.1e-16 59.5 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain Methyltransf_7 PF03492.10 EGC36743.1 - 6e-16 58.1 5.6 7.6e-14 51.2 0.6 2.0 2 0 0 2 2 2 2 SAM dependent carboxyl methyltransferase Methyltransf_31 PF13847.1 EGC36743.1 - 0.00016 21.2 1.9 0.0041 16.7 0.1 3.1 1 1 1 3 3 3 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36743.1 - 0.00063 20.1 0.0 0.0037 17.7 0.0 2.5 3 1 0 3 3 3 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36743.1 - 0.013 15.9 0.3 0.066 13.7 0.0 2.5 3 1 0 3 3 3 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC36743.1 - 0.057 13.1 0.0 0.11 12.2 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Ank_2 PF12796.2 EGC36744.1 - 1.8e-21 76.2 0.8 3.8e-12 46.3 0.0 2.8 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36744.1 - 4.5e-20 70.3 4.6 9.8e-10 37.7 0.2 5.2 5 0 0 5 5 5 4 Ankyrin repeat Ank_4 PF13637.1 EGC36744.1 - 6.7e-20 71.0 1.8 1.3e-08 35.1 0.1 4.3 2 2 1 3 3 3 3 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC36744.1 - 2.9e-15 55.9 3.9 4.3e-10 39.4 0.2 5.0 2 2 3 5 5 5 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC36744.1 - 3.6e-14 51.4 3.8 1.7e-05 24.5 0.1 5.3 5 0 0 5 5 5 4 Ankyrin repeat CN_hydrolase PF00795.17 EGC36744.1 - 2.1e-13 50.0 0.0 3.7e-13 49.2 0.0 1.3 1 0 0 1 1 1 1 Carbon-nitrogen hydrolase Skp1 PF01466.14 EGC36745.1 - 1.3e-09 37.9 0.5 1.3e-09 37.9 0.3 2.5 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGC36745.1 - 0.00083 19.4 1.2 0.0038 17.2 0.2 2.4 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Menin PF05053.8 EGC36745.1 - 0.018 13.2 7.4 0.023 12.9 5.1 1.1 1 0 0 1 1 1 0 Menin Peptidase_S49_N PF08496.5 EGC36745.1 - 1.9 8.2 13.8 0.092 12.5 5.3 2.0 2 0 0 2 2 2 0 Peptidase family S49 N-terminal PDGF_N PF04692.8 EGC36745.1 - 2.4 8.6 7.5 6.9 7.2 4.5 2.4 1 1 0 1 1 1 0 Platelet-derived growth factor, N terminal region PDCD2_C PF04194.8 EGC36746.1 - 7.3e-26 90.7 0.5 7.3e-26 90.7 0.3 4.0 2 1 0 3 3 3 2 Programmed cell death protein 2, C-terminal putative domain DZR PF12773.2 EGC36746.1 - 0.084 12.7 1.6 7.4 6.4 0.3 2.8 2 0 0 2 2 2 0 Double zinc ribbon F-112 PF09645.5 EGC36746.1 - 0.34 10.8 5.9 0.62 9.9 0.4 2.5 2 0 0 2 2 2 0 F-112 protein DUF3069 PF11269.3 EGC36746.1 - 1 9.4 3.8 12 5.9 0.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF3069) Avl9 PF09794.4 EGC36748.1 - 2.5e-38 131.5 4.5 2.5e-38 131.5 3.1 1.9 2 0 0 2 2 2 1 Transport protein Avl9 Y_phosphatase3 PF13350.1 EGC36749.1 - 5.1e-29 101.6 0.0 4e-16 59.7 0.0 2.3 2 0 0 2 2 2 2 Tyrosine phosphatase family Y_phosphatase3C PF13348.1 EGC36749.1 - 7.2e-09 35.6 0.0 2.5e-08 33.8 0.0 2.0 2 0 0 2 2 2 1 Tyrosine phosphatase family C-terminal region Y_phosphatase2 PF03162.8 EGC36749.1 - 5.7e-05 22.5 0.2 0.00085 18.7 0.0 2.5 3 0 0 3 3 3 1 Tyrosine phosphatase family GCV_T PF01571.16 EGC36751.1 - 4.8e-17 62.0 0.0 8.3e-17 61.2 0.0 1.4 1 1 0 1 1 1 1 Aminomethyltransferase folate-binding domain Propep_M14 PF02244.11 EGC36751.1 - 0.054 13.1 0.1 0.56 9.9 0.0 2.5 1 1 1 2 2 2 0 Carboxypeptidase activation peptide LeuA_dimer PF08502.5 EGC36751.1 - 0.1 12.4 0.1 0.18 11.5 0.1 1.4 1 0 0 1 1 1 0 LeuA allosteric (dimerisation) domain GCV_T_C PF08669.6 EGC36751.1 - 0.13 12.2 0.0 0.58 10.2 0.0 2.0 2 0 0 2 2 2 0 Glycine cleavage T-protein C-terminal barrel domain SR-25 PF10500.4 EGC36753.1 - 0.00082 18.9 9.9 0.0012 18.4 6.1 1.8 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Paramyxo_C PF01692.13 EGC36753.1 - 3.3 7.2 6.0 8.3 5.9 4.2 1.6 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c FNIP PF05725.7 EGC36754.1 - 5.5e-119 387.9 119.7 2.4e-13 49.7 0.9 15.1 8 3 8 17 17 17 17 FNIP Repeat DUF1769 PF08588.5 EGC36754.1 - 1.2e-07 31.5 13.5 0.053 13.4 0.0 9.5 8 2 2 11 11 11 2 Protein of unknown function (DUF1769) BTG PF07742.7 EGC36755.1 - 1.2e-08 34.5 0.0 1.7e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 BTG family ECH PF00378.15 EGC36756.1 - 1.5e-81 273.1 1.5 1.9e-81 272.7 1.1 1.0 1 0 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family ECH_C PF13766.1 EGC36756.1 - 2.5e-05 24.4 0.1 5.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 2-enoyl-CoA Hydratase C-terminal region Peptidase_S49 PF01343.13 EGC36756.1 - 0.00028 20.7 0.1 0.011 15.5 0.0 2.8 3 0 0 3 3 3 1 Peptidase family S49 SDH_sah PF01972.11 EGC36756.1 - 0.011 14.5 0.0 0.022 13.5 0.0 1.5 2 0 0 2 2 2 0 Serine dehydrogenase proteinase Cna_B PF05738.8 EGC36757.1 - 2.6e-09 36.6 5.0 5e-06 26.1 1.0 3.3 2 0 0 2 2 2 2 Cna protein B-type domain CarboxypepD_reg PF13620.1 EGC36757.1 - 2.2e-07 30.8 1.3 0.003 17.5 0.0 3.0 3 0 0 3 3 3 2 Carboxypeptidase regulatory-like domain Pentaxin PF00354.12 EGC36757.1 - 0.051 13.0 0.8 0.079 12.3 0.1 1.6 2 0 0 2 2 2 0 Pentaxin family DUF2012 PF09430.5 EGC36757.1 - 0.11 12.3 0.1 0.85 9.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2012) VPS9 PF02204.13 EGC36758.1 - 1.2e-30 105.5 1.4 2.8e-30 104.4 1.0 1.6 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain eIF-5a PF01287.15 EGC36759.1 - 3.2e-23 81.4 0.0 4.5e-23 80.9 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold KOW PF00467.24 EGC36759.1 - 0.00094 18.8 0.1 0.0022 17.6 0.1 1.6 1 0 0 1 1 1 1 KOW motif EFP_N PF08207.7 EGC36759.1 - 0.0021 17.8 0.0 0.0035 17.1 0.0 1.4 1 0 0 1 1 1 1 Elongation factor P (EF-P) KOW-like domain Glyco_transf_20 PF00982.16 EGC36760.1 - 1.5e-148 495.2 0.0 2.3e-148 494.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase family 20 Trehalose_PPase PF02358.11 EGC36760.1 - 5.7e-66 221.7 0.0 9.6e-66 221.0 0.0 1.4 1 0 0 1 1 1 1 Trehalose-phosphatase Hydrolase_3 PF08282.7 EGC36760.1 - 1.8e-05 24.4 0.1 0.04 13.4 0.1 2.8 2 1 0 3 3 3 2 haloacid dehalogenase-like hydrolase Glyco_transf_5 PF08323.6 EGC36760.1 - 0.17 11.3 0.5 0.46 9.9 0.1 1.8 2 0 0 2 2 2 0 Starch synthase catalytic domain Nop14 PF04147.7 EGC36761.1 - 0.0026 15.7 6.5 0.0031 15.5 4.5 1.3 1 0 0 1 1 1 1 Nop14-like family SPK PF04435.13 EGC36761.1 - 0.11 12.4 1.9 0.23 11.4 1.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF545) ADK PF00406.17 EGC36762.1 - 1.4e-09 37.9 0.5 1.9e-08 34.2 0.3 2.5 1 1 0 1 1 1 1 Adenylate kinase AAA_18 PF13238.1 EGC36762.1 - 1.1e-07 32.2 1.3 2.4e-07 31.1 0.0 2.2 3 0 0 3 3 3 1 AAA domain AAA_17 PF13207.1 EGC36762.1 - 0.00076 20.2 0.1 0.0023 18.7 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC36762.1 - 0.03 14.2 0.0 0.092 12.6 0.0 1.9 1 1 0 1 1 1 0 AAA domain Zeta_toxin PF06414.7 EGC36762.1 - 0.034 13.2 0.3 0.13 11.3 0.0 2.1 2 0 0 2 2 2 0 Zeta toxin HEAT PF02985.17 EGC36763.1 - 0.0021 17.9 0.2 3.4 7.9 0.0 3.6 3 0 0 3 3 3 2 HEAT repeat Arm PF00514.18 EGC36763.1 - 0.019 14.7 2.9 13 5.7 0.1 4.6 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat Ras PF00071.17 EGC36764.1 - 3.9e-32 110.8 0.8 4.2e-32 110.7 0.5 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC36764.1 - 1.2e-17 64.5 0.1 1.3e-17 64.3 0.1 1.0 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC36764.1 - 2.5e-09 36.6 0.6 2.8e-09 36.4 0.4 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC36764.1 - 2.1e-08 33.6 0.2 2.4e-08 33.4 0.1 1.0 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC36764.1 - 5.4e-07 29.5 0.0 6.9e-07 29.2 0.0 1.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC36764.1 - 4.4e-05 22.7 0.0 5.1e-05 22.5 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGC36764.1 - 0.00066 19.1 0.0 0.027 13.9 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Dynamin_N PF00350.18 EGC36764.1 - 0.0051 16.6 0.3 0.27 11.0 0.1 2.2 1 1 1 2 2 2 1 Dynamin family AAA_15 PF13175.1 EGC36764.1 - 0.014 14.4 0.2 0.016 14.2 0.1 1.2 1 1 0 1 1 1 0 AAA ATPase domain TK PF00265.13 EGC36764.1 - 0.014 14.9 0.0 0.016 14.7 0.0 1.0 1 0 0 1 1 1 0 Thymidine kinase PduV-EutP PF10662.4 EGC36764.1 - 0.026 14.0 0.1 0.045 13.2 0.0 1.6 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGC36764.1 - 0.044 13.0 0.0 1.1 8.5 0.0 2.0 1 1 1 2 2 2 0 Ferrous iron transport protein B VirE PF05272.6 EGC36764.1 - 0.058 12.8 0.1 0.071 12.5 0.1 1.1 1 0 0 1 1 1 0 Virulence-associated protein E Memo PF01875.12 EGC36765.1 - 2.9e-69 233.0 0.6 9.8e-68 227.9 0.4 2.0 1 1 0 1 1 1 1 Memo-like protein GCN5L1 PF06320.8 EGC36765.1 - 0.085 12.6 0.5 3.2 7.5 0.0 2.3 2 0 0 2 2 2 0 GCN5-like protein 1 (GCN5L1) zf-Tim10_DDP PF02953.10 EGC36766.1 - 7.1e-16 57.2 1.2 8e-16 57.0 0.8 1.1 1 0 0 1 1 1 1 Tim10/DDP family zinc finger DUF842 PF05811.8 EGC36766.1 - 0.016 14.7 0.8 0.018 14.4 0.5 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF842) DUF2116 PF09889.4 EGC36766.1 - 0.31 10.8 3.9 1.3 8.8 0.1 2.3 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) Pribosyltran PF00156.22 EGC36767.1 - 9.4e-15 54.4 0.1 1.2e-14 54.1 0.1 1.1 1 0 0 1 1 1 1 Phosphoribosyl transferase domain LRR_4 PF12799.2 EGC36768.1 - 1e-07 31.4 3.1 1e-07 31.4 2.1 5.2 2 1 2 4 4 4 2 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC36768.1 - 1.4e-05 24.7 1.9 1.4e-05 24.7 1.3 3.2 3 0 0 3 3 3 1 Leucine rich repeat LRR_9 PF14580.1 EGC36768.1 - 0.0044 16.6 1.6 0.0044 16.6 1.1 1.5 2 0 0 2 2 2 1 Leucine-rich repeat HTH_40 PF14493.1 EGC36768.1 - 0.1 12.8 1.9 0.59 10.3 0.1 2.4 2 0 0 2 2 2 0 Helix-turn-helix domain LRR_7 PF13504.1 EGC36768.1 - 0.13 12.5 9.7 0.97 9.9 0.0 4.7 5 0 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EGC36768.1 - 0.38 10.9 10.9 11 6.4 0.4 4.9 4 1 1 5 5 5 0 Leucine Rich repeat LRR_1 PF00560.28 EGC36768.1 - 0.7 10.1 13.2 0.3 11.2 0.3 4.6 4 1 0 4 4 4 0 Leucine Rich Repeat Leader_Thr PF08254.6 EGC36769.1 - 6.7 6.5 17.3 0.12 12.0 3.6 2.7 2 0 0 2 2 2 0 Threonine leader peptide BAF1_ABF1 PF04684.8 EGC36770.1 - 3.5 6.3 33.1 0.16 10.7 16.3 2.2 2 0 0 2 2 2 0 BAF1 / ABF1 chromatin reorganising factor FNIP PF05725.7 EGC36771.1 - 1.1e-108 355.0 76.4 7.9e-13 48.1 0.2 13.0 11 1 2 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC36771.1 - 0.00016 21.5 1.2 18 5.3 0.0 5.6 4 1 1 5 5 5 3 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC36771.1 - 0.00018 21.1 18.6 0.23 11.1 0.1 5.5 1 1 4 6 6 6 5 Leucine rich repeats (6 copies) U5_2-snRNA_bdg PF10597.4 EGC36772.1 - 0.012 15.1 0.8 0.036 13.6 0.6 1.8 1 0 0 1 1 1 0 U5-snRNA binding site 2 of PrP8 LRR_1 PF00560.28 EGC36773.1 - 5.4e-07 28.7 18.4 4.2 7.7 0.2 8.5 6 1 1 7 7 7 4 Leucine Rich Repeat LRR_6 PF13516.1 EGC36773.1 - 1.7e-05 24.3 34.6 0.2 11.7 0.7 8.9 8 0 0 8 8 8 4 Leucine Rich repeat LRR_4 PF12799.2 EGC36773.1 - 0.00032 20.2 34.5 0.0061 16.1 0.8 7.2 3 2 6 9 9 9 4 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGC36773.1 - 0.077 13.2 3.8 96 3.9 0.1 6.3 5 0 0 5 5 5 0 Leucine rich repeat adh_short PF00106.20 EGC36774.1 - 2.6e-23 82.7 0.0 3.5e-23 82.3 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36774.1 - 5.6e-19 68.8 0.0 6.9e-19 68.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36774.1 - 0.0005 19.7 0.0 0.00096 18.8 0.0 1.3 2 0 0 2 2 2 1 KR domain F420_oxidored PF03807.12 EGC36774.1 - 0.005 17.2 0.0 0.011 16.1 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Shikimate_DH PF01488.15 EGC36774.1 - 0.041 13.9 0.0 0.079 13.0 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HEAT PF02985.17 EGC36775.1 - 0.003 17.5 0.9 21 5.5 0.0 5.2 6 0 0 6 6 6 2 HEAT repeat zinc_ribbon_2 PF13240.1 EGC36776.1 - 0.00057 19.2 3.8 0.00098 18.5 2.6 1.4 1 0 0 1 1 1 1 zinc-ribbon domain DZR PF12773.2 EGC36776.1 - 0.00096 18.9 1.5 0.0017 18.1 1.0 1.4 1 0 0 1 1 1 1 Double zinc ribbon zf-ribbon_3 PF13248.1 EGC36776.1 - 0.0049 16.0 2.7 0.008 15.3 1.9 1.4 1 0 0 1 1 1 1 zinc-ribbon domain zf-RanBP PF00641.13 EGC36776.1 - 0.03 13.4 5.3 0.059 12.4 3.7 1.5 1 0 0 1 1 1 0 Zn-finger in Ran binding protein and others Epimerase PF01370.16 EGC36777.1 - 6.2e-22 78.1 0.0 1.1e-21 77.3 0.0 1.3 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC36777.1 - 1.2e-17 63.5 0.0 1.5e-17 63.1 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_4 PF07993.7 EGC36777.1 - 4e-15 55.4 0.0 1.4e-14 53.6 0.0 1.8 1 1 0 1 1 1 1 Male sterility protein NAD_binding_10 PF13460.1 EGC36777.1 - 4.9e-13 49.4 0.0 1e-12 48.4 0.0 1.6 1 1 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGC36777.1 - 3.2e-08 33.1 0.0 6.7e-08 32.0 0.0 1.6 2 0 0 2 2 2 1 NmrA-like family adh_short PF00106.20 EGC36777.1 - 2.1e-06 27.7 0.0 9.7e-06 25.5 0.0 2.0 1 1 0 1 1 1 1 short chain dehydrogenase Polysacc_synt_2 PF02719.10 EGC36777.1 - 2.8e-05 23.1 0.0 5.1e-05 22.3 0.0 1.4 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein RmlD_sub_bind PF04321.12 EGC36777.1 - 0.00097 18.1 0.3 0.011 14.6 0.2 2.1 1 1 0 1 1 1 1 RmlD substrate binding domain KR PF08659.5 EGC36777.1 - 0.0037 16.9 0.0 0.029 14.0 0.0 2.1 1 1 0 1 1 1 1 KR domain Ras PF00071.17 EGC36778.1 - 2.6e-64 215.4 0.3 3.1e-64 215.2 0.2 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC36778.1 - 8.6e-22 77.8 0.1 1.9e-21 76.7 0.0 1.6 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC36778.1 - 3.7e-19 68.6 0.1 4.6e-19 68.3 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC36778.1 - 5.9e-08 32.1 0.1 7.1e-08 31.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC36778.1 - 9e-07 28.5 0.2 2.2e-06 27.2 0.1 1.6 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC36778.1 - 3.2e-05 23.2 0.0 6.5e-05 22.2 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC36778.1 - 3.3e-05 23.8 0.0 6.5e-05 22.8 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC36778.1 - 0.00096 18.4 0.1 0.032 13.5 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B AAA PF00004.24 EGC36778.1 - 0.0011 19.2 0.0 0.78 9.9 0.0 2.2 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) G-alpha PF00503.15 EGC36778.1 - 0.0024 16.6 3.8 0.077 11.6 0.6 2.8 1 1 1 2 2 2 1 G-protein alpha subunit AAA_16 PF13191.1 EGC36778.1 - 0.0094 15.9 0.1 0.015 15.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGC36778.1 - 0.01 15.9 0.0 0.013 15.5 0.0 1.5 1 1 0 1 1 1 0 AAA domain DUF258 PF03193.11 EGC36778.1 - 0.018 14.2 0.0 0.037 13.2 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function, DUF258 RGP PF03214.8 EGC36778.1 - 0.019 13.7 0.1 0.031 13.0 0.0 1.3 1 1 0 1 1 1 0 Reversibly glycosylated polypeptide AAA_29 PF13555.1 EGC36778.1 - 0.028 13.9 0.0 0.078 12.5 0.0 1.7 1 0 0 1 1 1 0 P-loop containing region of AAA domain NACHT PF05729.7 EGC36778.1 - 0.061 12.9 0.0 0.1 12.2 0.0 1.3 1 0 0 1 1 1 0 NACHT domain ABC_tran PF00005.22 EGC36778.1 - 0.064 13.5 0.5 0.15 12.3 0.3 1.8 1 1 0 1 1 1 0 ABC transporter Coiled PF05710.7 EGC36779.1 - 0.0065 16.9 2.2 0.0066 16.8 1.5 1.1 1 0 0 1 1 1 1 Coiled coil XPG_N PF00752.12 EGC36780.1 - 2e-30 105.0 0.0 4.6e-30 103.8 0.0 1.6 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGC36780.1 - 3.2e-25 88.0 0.0 6.8e-25 86.9 0.0 1.6 1 0 0 1 1 1 1 XPG I-region 5_3_exonuc PF01367.15 EGC36780.1 - 3.3e-07 30.4 0.0 1.1e-06 28.7 0.0 2.0 1 0 0 1 1 1 1 5'-3' exonuclease, C-terminal SAM fold 5_3_exonuc_N PF02739.11 EGC36780.1 - 0.0035 16.7 0.0 0.0069 15.7 0.0 1.5 1 0 0 1 1 1 1 5'-3' exonuclease, N-terminal resolvase-like domain DUF3231 PF11553.3 EGC36780.1 - 0.0041 16.6 0.2 0.52 9.8 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF3231) DNA_pol_lambd_f PF10391.4 EGC36780.1 - 0.025 14.1 0.0 0.32 10.5 0.0 2.4 2 0 0 2 2 2 0 Fingers domain of DNA polymerase lambda HHH_5 PF14520.1 EGC36780.1 - 0.055 13.6 0.0 0.19 11.9 0.0 1.9 1 0 0 1 1 1 0 Helix-hairpin-helix domain Ribosomal_L10 PF00466.15 EGC36781.1 - 1.2e-20 73.3 0.1 1.7e-20 72.8 0.1 1.2 1 0 0 1 1 1 1 Ribosomal protein L10 TcdB_N PF12918.2 EGC36781.1 - 0.027 14.5 1.5 0.059 13.4 0.4 2.0 2 0 0 2 2 2 0 TcdB toxin N-terminal helical domain Cullin_binding PF03556.10 EGC36781.1 - 0.079 13.1 0.1 0.15 12.1 0.1 1.5 1 0 0 1 1 1 0 Cullin binding Arf PF00025.16 EGC36782.1 - 1.3e-35 122.2 0.2 1.4e-35 122.0 0.2 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC36782.1 - 9.6e-07 28.1 0.1 1.2e-06 27.8 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit NOG1 PF06858.9 EGC36782.1 - 0.00046 20.0 0.1 0.0013 18.5 0.1 1.8 1 0 0 1 1 1 1 Nucleolar GTP-binding protein 1 (NOG1) Ras PF00071.17 EGC36782.1 - 0.00087 18.7 0.0 0.001 18.4 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC36782.1 - 0.0099 15.0 0.1 0.011 14.8 0.1 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC36782.1 - 0.016 15.7 0.0 0.032 14.7 0.0 1.6 2 0 0 2 2 2 0 Miro-like protein G-alpha PF00503.15 EGC36782.1 - 0.018 13.7 4.8 0.051 12.2 1.3 2.2 1 1 1 2 2 2 0 G-protein alpha subunit MMR_HSR1 PF01926.18 EGC36782.1 - 0.049 13.5 0.7 0.16 11.9 0.3 2.1 2 1 0 2 2 2 0 50S ribosome-binding GTPase KAP_NTPase PF07693.9 EGC36782.1 - 0.064 12.2 0.1 0.092 11.7 0.1 1.2 1 0 0 1 1 1 0 KAP family P-loop domain Pkinase PF00069.20 EGC36783.1 - 1.6e-69 233.9 0.0 2.6e-69 233.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36783.1 - 1.8e-47 161.5 0.0 3e-47 160.8 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGC36783.1 - 1.1e-16 60.9 0.0 2.5e-16 59.8 0.0 1.6 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EGC36783.1 - 3.7e-07 29.3 0.0 9.5e-07 28.0 0.0 1.8 2 0 0 2 2 2 1 Kinase-like Seadorna_VP7 PF07387.6 EGC36783.1 - 0.008 15.0 0.0 0.015 14.1 0.0 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 APH PF01636.18 EGC36783.1 - 0.13 12.0 0.0 0.21 11.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family vMSA PF00695.14 EGC36784.1 - 2.8 7.0 9.3 3.4 6.7 6.4 1.1 1 0 0 1 1 1 0 Major surface antigen from hepadnavirus Homeobox PF00046.24 EGC36785.1 - 4.5e-05 22.9 1.4 8.2e-05 22.1 1.0 1.4 1 0 0 1 1 1 1 Homeobox domain Spt5_N PF11942.3 EGC36785.1 - 0.017 15.7 8.2 0.017 15.7 5.6 1.7 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Phage_capsid PF05065.8 EGC36785.1 - 0.043 12.9 0.3 0.046 12.9 0.2 1.2 1 0 0 1 1 1 0 Phage capsid family YL1 PF05764.8 EGC36785.1 - 0.081 12.5 8.1 0.1 12.1 5.6 1.2 1 0 0 1 1 1 0 YL1 nuclear protein DUF2457 PF10446.4 EGC36785.1 - 0.18 10.5 15.3 0.23 10.1 10.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) CDC45 PF02724.9 EGC36785.1 - 0.57 8.1 6.4 0.7 7.8 4.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Nucleoplasmin PF03066.10 EGC36785.1 - 9.9 5.6 10.2 18 4.8 7.1 1.3 1 0 0 1 1 1 0 Nucleoplasmin RasGAP PF00616.14 EGC36786.1 - 1.3e-55 188.1 0.2 1.3e-55 188.1 0.2 2.8 3 0 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase RasGAP_C PF03836.10 EGC36786.1 - 1.1e-30 106.2 13.9 3.4e-30 104.5 9.7 1.9 1 0 0 1 1 1 1 RasGAP C-terminus DUF972 PF06156.8 EGC36786.1 - 0.0072 16.6 5.8 0.0072 16.6 4.0 4.2 5 0 0 5 5 5 1 Protein of unknown function (DUF972) DUF3437 PF11919.3 EGC36786.1 - 0.047 13.3 0.0 0.39 10.4 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3437) EST1 PF10374.4 EGC36786.1 - 0.16 11.9 6.7 0.59 10.1 3.5 2.8 3 0 0 3 3 3 0 Telomerase activating protein Est1 DNA_pol_alpha_N PF12254.3 EGC36787.1 - 0.069 12.9 1.5 0.12 12.2 1.0 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit p180 N terminal DUF4047 PF13256.1 EGC36787.1 - 0.092 12.6 0.6 0.096 12.6 0.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) adh_short PF00106.20 EGC36788.1 - 3.2e-27 95.5 0.0 4e-27 95.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36788.1 - 2e-14 53.9 0.1 2.5e-14 53.6 0.1 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36788.1 - 6.3e-10 39.0 0.0 8.9e-10 38.5 0.0 1.2 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC36788.1 - 6.1e-07 29.6 0.0 9.4e-07 29.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding DUF1776 PF08643.5 EGC36788.1 - 1.1e-06 28.0 0.0 1.9e-06 27.2 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC36788.1 - 2e-06 27.4 0.0 7.6e-06 25.5 0.1 2.0 2 1 0 2 2 2 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGC36788.1 - 0.0064 15.4 0.1 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain NmrA PF05368.8 EGC36788.1 - 0.068 12.4 0.4 0.13 11.4 0.2 1.6 2 0 0 2 2 2 0 NmrA-like family ADH_zinc_N PF00107.21 EGC36788.1 - 0.076 12.5 0.5 0.22 11.0 0.2 1.9 1 1 1 2 2 2 0 Zinc-binding dehydrogenase adh_short PF00106.20 EGC36789.1 - 1.3e-26 93.4 0.0 1.7e-26 93.1 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36789.1 - 1.2e-16 61.1 0.1 2.3e-16 60.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36789.1 - 1.4e-08 34.6 0.0 2e-08 34.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC36789.1 - 2.1e-08 33.6 0.0 1.2e-07 31.1 0.0 1.9 2 0 0 2 2 2 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC36789.1 - 5.8e-07 29.6 0.1 1.4e-06 28.4 0.1 1.8 1 1 1 2 2 2 1 NADH(P)-binding Epimerase PF01370.16 EGC36789.1 - 5.4e-05 22.7 0.2 9.8e-05 21.8 0.2 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC36789.1 - 0.044 12.6 0.3 0.07 12.0 0.2 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGC36789.1 - 0.088 11.4 0.2 0.13 10.9 0.2 1.3 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family WD40 PF00400.27 EGC36790.1 - 3.2e-08 33.1 11.2 0.065 13.1 0.0 7.0 6 1 0 6 6 6 3 WD domain, G-beta repeat TPR_2 PF07719.12 EGC36790.1 - 0.26 11.2 0.6 0.79 9.7 0.4 1.8 1 0 0 1 1 1 0 Tetratricopeptide repeat BPL_LplA_LipB PF03099.14 EGC36791.1 - 8.2e-18 64.6 0.1 1.6e-17 63.6 0.0 1.5 1 0 0 1 1 1 1 Biotin/lipoate A/B protein ligase family BPL_C PF02237.12 EGC36791.1 - 5.9e-09 35.4 0.1 1.6e-08 34.1 0.1 1.7 1 0 0 1 1 1 1 Biotin protein ligase C terminal domain DUF4416 PF14385.1 EGC36791.1 - 0.032 13.9 0.3 0.2 11.3 0.0 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4416) SAM_PNT PF02198.11 EGC36792.1 - 1.7e-08 34.0 0.2 6.4e-08 32.2 0.1 2.0 1 0 0 1 1 1 1 Sterile alpha motif (SAM)/Pointed domain Trypsin_2 PF13365.1 EGC36792.1 - 0.00058 19.8 0.3 0.0026 17.7 0.2 2.1 1 1 0 1 1 1 1 Trypsin-like peptidase domain DUF2201_N PF13203.1 EGC36792.1 - 0.076 12.1 1.9 0.11 11.6 1.3 1.1 1 0 0 1 1 1 0 Putative metallopeptidase domain SR-25 PF10500.4 EGC36792.1 - 0.22 10.9 10.5 0.36 10.2 7.3 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CAF-1_p150 PF11600.3 EGC36792.1 - 5.3 6.3 11.0 8.9 5.6 7.6 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal ECH PF00378.15 EGC36793.1 - 1.7e-14 53.5 0.0 1.2e-13 50.7 0.0 2.0 1 1 0 1 1 1 1 Enoyl-CoA hydratase/isomerase family DUF3741 PF12552.3 EGC36793.1 - 0.13 12.0 0.4 0.26 11.0 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3741) PDEase_II PF02112.10 EGC36794.1 - 5.2e-102 341.1 1.2 6.8e-102 340.8 0.8 1.1 1 0 0 1 1 1 1 cAMP phosphodiesterases class-II Lactamase_B_2 PF12706.2 EGC36794.1 - 2.1e-05 24.1 0.5 0.0004 19.9 0.2 2.5 1 1 1 2 2 2 1 Beta-lactamase superfamily domain EGF_2 PF07974.8 EGC36795.1 - 7.4e-08 32.4 29.1 3.5e-05 23.8 9.0 2.8 2 0 0 2 2 2 2 EGF-like domain TIG PF01833.19 EGC36795.1 - 0.00043 20.2 3.3 0.00043 20.2 2.3 4.8 5 1 0 5 5 5 1 IPT/TIG domain Laminin_EGF PF00053.19 EGC36795.1 - 0.0029 17.4 22.6 0.19 11.6 2.9 3.0 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) LRR_4 PF12799.2 EGC36795.1 - 0.0036 16.9 3.1 0.0036 16.9 2.1 4.9 7 0 0 7 7 7 1 Leucine Rich repeats (2 copies) hEGF PF12661.2 EGC36795.1 - 0.03 14.3 12.3 0.085 12.9 1.5 2.7 2 0 0 2 2 2 0 Human growth factor-like EGF EGF PF00008.22 EGC36795.1 - 0.26 11.3 22.5 0.07 13.1 4.9 3.1 3 0 0 3 3 3 0 EGF-like domain FMO-like PF00743.14 EGC36796.1 - 3.4e-61 207.0 3.3 4.1e-61 206.7 2.3 1.0 1 0 0 1 1 1 1 Flavin-binding monooxygenase-like Pyr_redox_3 PF13738.1 EGC36796.1 - 9.9e-18 64.9 0.0 2.7e-16 60.2 0.0 2.3 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase K_oxygenase PF13434.1 EGC36796.1 - 8.2e-11 41.3 1.9 1.5e-08 33.9 0.6 2.9 2 1 0 2 2 2 1 L-lysine 6-monooxygenase (NADPH-requiring) Pyr_redox_2 PF07992.9 EGC36796.1 - 2.7e-10 40.4 0.0 1.7e-07 31.3 0.0 2.3 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC36796.1 - 4.4e-06 26.6 0.0 1e-05 25.4 0.0 1.6 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain NAD_binding_9 PF13454.1 EGC36796.1 - 4.9e-05 23.1 0.0 0.0057 16.4 0.0 2.7 2 1 0 2 2 2 1 FAD-NAD(P)-binding HI0933_like PF03486.9 EGC36796.1 - 5.3e-05 21.8 0.1 0.0024 16.4 0.0 2.8 3 0 0 3 3 3 1 HI0933-like protein Pyr_redox PF00070.22 EGC36796.1 - 0.00062 20.1 0.0 0.4 11.1 0.0 3.0 3 0 0 3 3 2 1 Pyridine nucleotide-disulphide oxidoreductase FAD_binding_2 PF00890.19 EGC36796.1 - 0.0047 15.8 0.0 0.007 15.2 0.0 1.2 1 0 0 1 1 1 1 FAD binding domain FAD_oxidored PF12831.2 EGC36796.1 - 0.02 13.9 0.0 0.036 13.1 0.0 1.5 1 0 0 1 1 1 0 FAD dependent oxidoreductase NAD_binding_10 PF13460.1 EGC36796.1 - 0.02 14.8 0.0 0.74 9.7 0.0 2.2 2 0 0 2 2 2 0 NADH(P)-binding NAD_binding_7 PF13241.1 EGC36796.1 - 0.029 14.6 0.0 1.7 8.9 0.0 3.1 2 1 0 2 2 2 0 Putative NAD(P)-binding DAO PF01266.19 EGC36796.1 - 0.04 12.8 0.0 0.56 9.0 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase Thi4 PF01946.12 EGC36796.1 - 0.12 11.4 0.0 0.24 10.4 0.0 1.5 1 0 0 1 1 1 0 Thi4 family DUF1049 PF06305.6 EGC36797.1 - 0.044 13.2 1.3 0.081 12.4 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1049) HIT PF01230.18 EGC36798.1 - 3.8e-22 78.6 0.1 4.7e-22 78.3 0.0 1.1 1 0 0 1 1 1 1 HIT domain DcpS_C PF11969.3 EGC36798.1 - 2.2e-15 56.9 0.0 2.9e-15 56.5 0.0 1.1 1 0 0 1 1 1 1 Scavenger mRNA decapping enzyme C-term binding Cytochrom_B559 PF00283.14 EGC36798.1 - 2.8 7.3 5.2 3.3 7.0 0.5 2.4 2 0 0 2 2 2 0 Cytochrome b559, alpha (gene psbE) and beta (gene psbF)subunits NAD_binding_4 PF07993.7 EGC36799.1 - 3.4e-59 199.7 0.0 5.4e-59 199.1 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyltransferase PF01553.16 EGC36799.1 - 1.3e-22 79.6 0.0 3e-22 78.4 0.0 1.6 1 0 0 1 1 1 1 Acyltransferase Sterile PF03015.14 EGC36799.1 - 4.1e-10 39.7 0.1 1.4e-09 38.1 0.0 2.0 1 0 0 1 1 1 1 Male sterility protein Epimerase PF01370.16 EGC36799.1 - 3e-07 30.1 0.0 2.6e-06 27.0 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC36799.1 - 6.3e-05 21.8 0.3 0.007 15.0 0.3 2.8 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGC36799.1 - 0.045 12.6 0.0 0.1 11.4 0.0 1.6 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC36800.1 - 1.9e-26 92.9 0.0 2.8e-26 92.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC36800.1 - 8.1e-15 55.2 0.0 1.1e-14 54.7 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC36800.1 - 1.4e-07 31.3 0.0 3e-07 30.2 0.0 1.4 1 1 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC36800.1 - 3e-06 26.5 0.0 2.8e-05 23.3 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NmrA PF05368.8 EGC36800.1 - 4.3e-05 22.8 0.0 7.1e-05 22.1 0.0 1.3 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC36800.1 - 0.00017 21.6 0.0 0.00022 21.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC36800.1 - 0.025 13.4 0.0 0.034 13.0 0.0 1.1 1 0 0 1 1 1 0 RmlD substrate binding domain Eno-Rase_NADH_b PF12242.3 EGC36800.1 - 0.093 12.5 0.1 0.22 11.3 0.1 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase zf-LITAF-like PF10601.4 EGC36801.1 - 4e-21 74.6 11.5 4.2e-21 74.5 8.0 1.0 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain PIG-F PF06699.6 EGC36801.1 - 0.012 15.5 0.4 0.013 15.4 0.3 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F RecR PF02132.10 EGC36801.1 - 0.096 12.1 0.1 0.096 12.1 0.1 1.7 2 0 0 2 2 2 0 RecR protein zinc_ribbon_2 PF13240.1 EGC36801.1 - 0.11 12.0 3.3 2.1 7.9 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain DcuA_DcuB PF03605.9 EGC36801.1 - 0.13 11.1 0.0 0.13 11.0 0.0 1.0 1 0 0 1 1 1 0 Anaerobic c4-dicarboxylate membrane transporter zf-DNL PF05180.7 EGC36801.1 - 1.2 8.8 5.1 2.2 8.0 0.3 2.2 2 0 0 2 2 2 0 DNL zinc finger DZR PF12773.2 EGC36801.1 - 3.9 7.3 6.3 13 5.7 4.4 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2_6 PF13912.1 EGC36801.1 - 8.8 6.3 7.6 2.1 8.3 0.6 2.5 2 0 0 2 2 2 0 C2H2-type zinc finger Ank_3 PF13606.1 EGC36802.1 - 0.037 14.2 1.7 3.9 7.9 0.0 4.4 4 0 0 4 4 4 0 Ankyrin repeat Myosin_head PF00063.16 EGC36803.1 - 1.5e-264 879.3 0.3 1.5e-264 879.3 0.2 1.6 2 1 0 2 2 2 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC36803.1 - 2.7e-57 193.3 7.9 4.3e-57 192.6 5.4 1.3 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EGC36803.1 - 1.1e-16 59.9 0.3 8.8e-16 57.0 0.1 2.3 2 0 0 2 2 2 1 SH3 domain SH3_9 PF14604.1 EGC36803.1 - 6.8e-16 57.5 0.7 2e-15 56.0 0.1 2.1 2 0 0 2 2 2 1 Variant SH3 domain SH3_2 PF07653.12 EGC36803.1 - 1.3e-09 37.3 0.0 3.8e-09 35.9 0.0 1.9 1 0 0 1 1 1 1 Variant SH3 domain ABC_tran PF00005.22 EGC36803.1 - 0.0057 16.9 0.0 0.022 15.0 0.0 2.1 1 0 0 1 1 1 1 ABC transporter Zeta_toxin PF06414.7 EGC36803.1 - 0.0099 14.9 0.0 0.024 13.7 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_17 PF13207.1 EGC36803.1 - 0.017 15.9 0.0 0.28 12.0 0.0 2.9 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGC36803.1 - 0.03 14.4 0.0 0.11 12.5 0.0 2.0 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC36803.1 - 0.062 13.6 0.0 0.26 11.5 0.0 2.2 1 0 0 1 1 1 0 AAA domain DUF605 PF04652.11 EGC36803.1 - 0.14 11.5 15.1 0.26 10.6 10.5 1.4 1 0 0 1 1 1 0 Vta1 like AAA_16 PF13191.1 EGC36803.1 - 0.19 11.7 0.0 0.52 10.2 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain PDEase_I PF00233.14 EGC36805.1 - 4.8e-71 239.2 0.9 4.8e-71 239.2 0.6 2.2 2 0 0 2 2 2 1 3'5'-cyclic nucleotide phosphodiesterase PDEase_I_N PF08499.7 EGC36805.1 - 2.5e-08 33.6 0.3 2.5e-08 33.6 0.2 4.1 3 0 0 3 3 3 1 3'5'-cyclic nucleotide phosphodiesterase N-terminal PARP PF00644.15 EGC36806.1 - 1.1e-21 77.1 0.0 4e-21 75.4 0.0 2.0 1 1 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC36806.1 - 4.3e-14 52.3 0.1 1.3e-13 50.7 0.1 1.9 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain Ank_5 PF13857.1 EGC36806.1 - 1.9e-07 31.1 0.1 2.1e-05 24.5 0.0 3.4 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC36806.1 - 4.5e-07 30.1 0.0 6.4e-05 23.2 0.0 2.8 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) BRCT PF00533.21 EGC36806.1 - 7e-07 29.3 0.9 7e-07 29.3 0.6 2.8 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain WGR PF05406.10 EGC36806.1 - 5e-06 26.3 0.2 1.1e-05 25.2 0.1 1.5 1 0 0 1 1 1 1 WGR domain Ank_4 PF13637.1 EGC36806.1 - 1.3e-05 25.6 0.1 0.0037 17.7 0.0 3.5 3 0 0 3 3 3 1 Ankyrin repeats (many copies) Ank PF00023.25 EGC36806.1 - 0.00021 20.9 0.1 0.0016 18.1 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeat Ank_3 PF13606.1 EGC36806.1 - 0.00027 20.8 1.3 0.052 13.8 0.0 3.7 4 0 0 4 4 4 1 Ankyrin repeat PTCB-BRCT PF12738.2 EGC36806.1 - 0.0036 17.1 0.1 0.019 14.7 0.0 2.3 2 0 0 2 2 2 1 twin BRCT domain Pkinase PF00069.20 EGC36807.1 - 5.2e-42 143.7 0.0 5.8e-42 143.6 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36807.1 - 3.3e-41 141.0 0.0 3.7e-41 140.9 0.0 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Alba PF01918.16 EGC36808.1 - 1.2e-10 40.7 0.0 2.4e-10 39.8 0.0 1.5 1 0 0 1 1 1 1 Alba Rpp20 PF12328.3 EGC36808.1 - 0.0001 21.9 10.7 0.00017 21.2 0.0 3.8 3 1 0 3 3 3 1 Rpp20 subunit of nuclear RNase MRP and P BCS1_N PF08740.6 EGC36809.1 - 7.5e-36 123.5 0.0 1.4e-35 122.6 0.0 1.5 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGC36809.1 - 7.6e-22 77.9 0.1 1.4e-20 73.8 0.0 2.3 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF815 PF05673.8 EGC36809.1 - 3.4e-06 26.1 0.1 1.7e-05 23.8 0.1 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGC36809.1 - 0.0011 19.2 0.5 0.006 16.8 0.2 2.3 2 1 0 2 2 2 1 ABC transporter MMR_HSR1 PF01926.18 EGC36809.1 - 0.0024 17.8 0.1 0.01 15.7 0.1 2.2 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGC36809.1 - 0.0025 17.2 0.0 0.0058 16.1 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC36809.1 - 0.0031 17.5 0.0 0.0078 16.2 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain RuvB_N PF05496.7 EGC36809.1 - 0.0061 15.6 0.0 0.01 14.9 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGC36809.1 - 0.012 15.3 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) DUF258 PF03193.11 EGC36809.1 - 0.013 14.7 0.0 0.035 13.3 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC36809.1 - 0.016 15.3 0.0 0.06 13.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGC36809.1 - 0.016 16.0 0.2 0.067 14.0 0.0 2.2 3 0 0 3 3 2 0 AAA domain DDRGK PF09756.4 EGC36809.1 - 0.018 14.4 0.2 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 DDRGK domain AAA_19 PF13245.1 EGC36809.1 - 0.025 14.3 0.0 0.14 11.9 0.0 2.3 2 1 0 2 2 1 0 Part of AAA domain RNA_helicase PF00910.17 EGC36809.1 - 0.038 14.1 0.0 0.12 12.5 0.0 2.0 1 0 0 1 1 1 0 RNA helicase AAA_25 PF13481.1 EGC36809.1 - 0.043 13.2 0.0 0.11 11.8 0.0 1.7 2 0 0 2 2 2 0 AAA domain AAA_24 PF13479.1 EGC36809.1 - 0.093 12.3 0.0 0.3 10.6 0.0 1.9 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGC36809.1 - 0.11 11.5 0.0 0.24 10.4 0.0 1.6 1 0 0 1 1 1 0 KaiC AAA_23 PF13476.1 EGC36809.1 - 0.47 10.7 5.3 0.18 12.0 0.8 2.3 2 2 0 2 2 2 0 AAA domain FAD_binding_3 PF01494.14 EGC36810.1 - 1.2e-18 67.3 0.0 1e-17 64.2 0.0 2.3 1 1 0 1 1 1 1 FAD binding domain Shikimate_DH PF01488.15 EGC36810.1 - 7.8e-05 22.7 0.1 0.00021 21.4 0.0 1.8 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase DAO PF01266.19 EGC36810.1 - 8.9e-05 21.5 0.0 0.0069 15.3 0.1 2.3 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGC36810.1 - 0.00012 22.0 0.0 0.00029 20.7 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC36810.1 - 0.0035 17.7 0.4 0.06 13.7 0.1 2.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase Rot1 PF10681.4 EGC36810.1 - 0.0035 16.7 0.1 0.02 14.2 0.0 1.9 2 0 0 2 2 2 1 Chaperone for protein-folding within the ER, fungal Pyr_redox_3 PF13738.1 EGC36810.1 - 0.0041 17.2 0.0 0.0091 16.0 0.0 1.6 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_7 PF13241.1 EGC36810.1 - 0.0047 17.1 0.0 0.035 14.3 0.0 2.3 2 0 0 2 2 2 1 Putative NAD(P)-binding TrkA_N PF02254.13 EGC36810.1 - 0.005 16.8 0.1 0.031 14.2 0.1 2.1 2 0 0 2 2 2 1 TrkA-N domain Lycopene_cycl PF05834.7 EGC36810.1 - 0.0056 15.6 0.1 1.2 7.9 0.1 2.6 3 0 0 3 3 3 1 Lycopene cyclase protein Thi4 PF01946.12 EGC36810.1 - 0.0062 15.6 0.2 0.012 14.6 0.0 1.5 2 0 0 2 2 2 1 Thi4 family NAD_binding_8 PF13450.1 EGC36810.1 - 0.012 15.6 0.0 0.024 14.6 0.0 1.5 1 0 0 1 1 1 0 NAD(P)-binding Rossmann-like domain DUF918 PF06033.6 EGC36810.1 - 0.021 14.3 0.0 0.058 12.9 0.0 1.7 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF918) SE PF08491.5 EGC36810.1 - 0.025 13.4 0.0 0.067 11.9 0.0 1.6 2 0 0 2 2 2 0 Squalene epoxidase HI0933_like PF03486.9 EGC36810.1 - 0.059 11.8 0.2 0.53 8.6 0.1 2.1 2 0 0 2 2 2 0 HI0933-like protein FAD_binding_2 PF00890.19 EGC36810.1 - 0.065 12.0 0.1 0.11 11.2 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain Spermine_synth PF01564.12 EGC36810.1 - 0.075 11.9 0.6 0.14 11.0 0.4 1.4 1 0 0 1 1 1 0 Spermine/spermidine synthase F420_oxidored PF03807.12 EGC36810.1 - 0.077 13.4 0.1 0.27 11.6 0.0 1.9 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent ThiF PF00899.16 EGC36810.1 - 0.084 12.6 0.2 0.26 11.1 0.1 1.9 2 0 0 2 2 2 0 ThiF family Condensin2nSMC PF12422.3 EGC36811.1 - 0.39 10.4 4.0 0.17 11.5 0.2 2.1 3 0 0 3 3 3 0 Condensin II non structural maintenance of chromosomes subunit UFC1 PF08694.6 EGC36812.1 - 2.8e-87 290.1 1.1 3.1e-87 290.0 0.7 1.0 1 0 0 1 1 1 1 Ubiquitin-fold modifier-conjugating enzyme 1 RWD PF05773.17 EGC36812.1 - 0.0066 16.3 0.2 0.013 15.3 0.2 1.6 1 1 0 1 1 1 1 RWD domain UQ_con PF00179.21 EGC36812.1 - 0.014 14.8 1.0 0.031 13.7 0.7 1.6 1 1 0 1 1 1 0 Ubiquitin-conjugating enzyme Spc42p PF11544.3 EGC36812.1 - 0.08 12.8 0.1 0.13 12.1 0.1 1.3 1 0 0 1 1 1 0 Spindle pole body component Spc42p BRCT PF00533.21 EGC36813.1 - 4.6e-10 39.4 0.0 7e-10 38.9 0.0 1.2 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC36813.1 - 0.068 13.0 0.0 0.1 12.4 0.0 1.3 1 0 0 1 1 1 0 twin BRCT domain FNIP PF05725.7 EGC36814.1 - 5.9e-102 333.4 62.8 2.5e-18 65.7 0.4 10.4 5 2 7 12 12 12 12 FNIP Repeat DUF1769 PF08588.5 EGC36814.1 - 1.3e-05 25.0 4.7 4.4 7.3 0.0 7.0 6 3 2 8 8 8 2 Protein of unknown function (DUF1769) Pescadillo_N PF06732.6 EGC36815.1 - 1.4e-97 326.3 15.1 1.4e-97 326.3 10.4 3.2 2 1 2 4 4 4 1 Pescadillo N-terminus BRCT PF00533.21 EGC36815.1 - 4.5e-08 33.1 0.1 2.4e-07 30.7 0.0 2.4 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Yippee-Mis18 PF03226.9 EGC36816.1 - 1.5e-20 73.0 1.7 1.5e-20 73.0 1.2 2.1 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly MAT1 PF06391.8 EGC36817.1 - 4.9e-28 98.0 28.0 4.9e-28 98.0 19.4 1.6 1 1 1 2 2 2 1 CDK-activating kinase assembly factor MAT1 SET PF00856.23 EGC36818.1 - 3e-24 86.1 0.4 3e-24 86.1 0.3 4.9 4 1 0 4 4 4 1 SET domain RRM_5 PF13893.1 EGC36818.1 - 0.097 12.5 0.0 0.21 11.4 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) A_deaminase PF00962.17 EGC36820.1 - 4.1e-103 344.7 0.5 6.2e-103 344.1 0.3 1.3 1 0 0 1 1 1 1 Adenosine/AMP deaminase CMAS PF02353.15 EGC36822.1 - 6.2e-76 255.0 1.0 7.9e-76 254.7 0.7 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGC36822.1 - 1.2e-13 51.0 0.0 2e-13 50.3 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC36822.1 - 5.5e-10 39.8 0.0 1.3e-09 38.6 0.0 1.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC36822.1 - 5.3e-09 36.4 0.0 2.3e-08 34.4 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC36822.1 - 6.6e-07 29.0 0.1 1.6e-06 27.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC36822.1 - 1.8e-06 28.3 0.0 4.8e-06 26.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC36822.1 - 5.8e-05 23.1 0.0 0.00015 21.7 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain MTS PF05175.9 EGC36822.1 - 0.00015 21.1 0.0 0.00026 20.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGC36822.1 - 0.00036 20.8 0.0 0.00085 19.6 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGC36822.1 - 0.00065 19.0 0.0 0.0018 17.6 0.0 1.7 1 0 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_4 PF02390.12 EGC36822.1 - 0.0047 15.9 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Putative methyltransferase UPF0020 PF01170.13 EGC36822.1 - 0.017 14.6 0.0 0.033 13.7 0.0 1.4 1 0 0 1 1 1 0 Putative RNA methylase family UPF0020 ADH_zinc_N PF00107.21 EGC36822.1 - 0.038 13.5 0.0 0.069 12.7 0.0 1.6 1 1 0 1 1 1 0 Zinc-binding dehydrogenase MetW PF07021.7 EGC36822.1 - 0.058 12.7 0.0 0.099 12.0 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0146 PF03686.8 EGC36822.1 - 0.14 11.9 0.0 0.29 10.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0146) FAD_binding_3 PF01494.14 EGC36823.1 - 7.7e-24 84.3 0.0 2.7e-23 82.5 0.0 1.9 1 1 0 1 1 1 1 FAD binding domain Lycopene_cycl PF05834.7 EGC36823.1 - 1e-05 24.6 0.0 9.6e-05 21.4 0.0 2.1 1 1 0 1 1 1 1 Lycopene cyclase protein Trp_halogenase PF04820.9 EGC36823.1 - 1.2e-05 24.1 0.1 0.012 14.2 0.0 3.0 3 0 0 3 3 3 1 Tryptophan halogenase DAO PF01266.19 EGC36823.1 - 0.0001 21.3 0.0 0.0035 16.3 0.0 2.2 2 0 0 2 2 2 1 FAD dependent oxidoreductase Pyr_redox_2 PF07992.9 EGC36823.1 - 0.00018 21.4 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Thi4 PF01946.12 EGC36823.1 - 0.0002 20.5 0.1 0.00031 19.9 0.1 1.4 1 0 0 1 1 1 1 Thi4 family Pyr_redox_3 PF13738.1 EGC36823.1 - 0.00061 19.9 0.0 0.00091 19.3 0.0 1.3 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_8 PF13450.1 EGC36823.1 - 0.0014 18.6 0.0 0.0029 17.5 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain TrkA_N PF02254.13 EGC36823.1 - 0.0093 15.9 0.1 0.022 14.7 0.0 1.6 1 0 0 1 1 1 1 TrkA-N domain Shikimate_DH PF01488.15 EGC36823.1 - 0.014 15.4 0.2 0.04 14.0 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase HI0933_like PF03486.9 EGC36823.1 - 0.046 12.1 0.3 0.11 10.9 0.0 1.7 2 0 0 2 2 2 0 HI0933-like protein SE PF08491.5 EGC36823.1 - 0.053 12.3 0.0 0.23 10.2 0.0 1.8 2 0 0 2 2 2 0 Squalene epoxidase NAD_binding_7 PF13241.1 EGC36823.1 - 0.058 13.6 0.0 0.15 12.3 0.0 1.9 1 1 0 1 1 1 0 Putative NAD(P)-binding Pyr_redox PF00070.22 EGC36823.1 - 0.061 13.7 0.0 0.22 11.9 0.0 2.0 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase NAD_binding_9 PF13454.1 EGC36823.1 - 0.076 12.7 0.2 1.2 8.9 0.0 2.3 2 0 0 2 2 2 0 FAD-NAD(P)-binding ACP_syn_III PF08545.5 EGC36823.1 - 0.11 12.1 0.0 3 7.5 0.0 2.7 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III FAD_binding_2 PF00890.19 EGC36823.1 - 0.12 11.2 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain BHD_3 PF10405.4 EGC36824.1 - 2.1e-23 81.8 0.0 4.5e-23 80.7 0.0 1.6 1 0 0 1 1 1 1 Rad4 beta-hairpin domain 3 Rad4 PF03835.10 EGC36824.1 - 4.3e-19 68.3 3.1 4.3e-19 68.3 2.1 4.1 3 1 1 4 4 4 1 Rad4 transglutaminase-like domain BHD_1 PF10403.4 EGC36824.1 - 2.8e-12 45.9 1.4 6e-11 41.6 0.3 3.1 2 0 0 2 2 2 1 Rad4 beta-hairpin domain 1 BHD_2 PF10404.4 EGC36824.1 - 8.2e-08 32.4 0.1 8.2e-08 32.4 0.1 4.1 3 0 0 3 3 3 1 Rad4 beta-hairpin domain 2 Patatin PF01734.17 EGC36825.1 - 1.4 8.8 3.6 5 7.0 2.5 1.9 1 0 0 1 1 1 0 Patatin-like phospholipase SNF2_N PF00176.18 EGC36826.1 - 1.1e-72 244.4 3.5 1.1e-72 244.4 2.4 2.5 2 0 0 2 2 2 1 SNF2 family N-terminal domain DBINO PF13892.1 EGC36826.1 - 1.3e-45 154.8 25.0 1.3e-45 154.8 17.3 3.8 3 0 0 3 3 3 1 DNA-binding domain Helicase_C PF00271.26 EGC36826.1 - 8.2e-15 54.4 0.0 4.5e-13 48.8 0.0 3.2 2 0 0 2 2 2 1 Helicase conserved C-terminal domain WWE PF02825.15 EGC36827.1 - 2.9e-08 33.0 3.8 7.2e-08 31.7 2.6 1.7 1 0 0 1 1 1 1 WWE domain EF-hand_7 PF13499.1 EGC36827.1 - 0.00012 22.1 0.3 0.00028 20.9 0.2 1.7 1 0 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC36827.1 - 0.0014 17.8 2.9 0.0018 17.4 0.5 2.3 2 0 0 2 2 2 1 EF hand EF-hand_8 PF13833.1 EGC36827.1 - 0.033 13.8 1.4 0.72 9.5 0.7 2.8 2 1 0 2 2 2 0 EF-hand domain pair DUF2944 PF11161.3 EGC36827.1 - 0.054 13.1 2.3 0.37 10.4 0.0 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2946) EF-hand_like PF09279.6 EGC36827.1 - 0.06 13.3 2.5 0.17 11.9 0.1 2.4 2 0 0 2 2 2 0 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_6 PF13405.1 EGC36827.1 - 0.1 12.5 0.5 1.4 8.9 0.1 2.6 2 0 0 2 2 2 0 EF-hand domain Urm1 PF09138.6 EGC36827.1 - 0.11 12.6 2.6 1.3 9.2 0.6 2.9 1 1 1 2 2 2 0 Urm1 (Ubiquitin related modifier) TP53IP5 PF15331.1 EGC36827.1 - 0.19 11.5 11.9 0.34 10.8 7.9 1.6 2 0 0 2 2 2 0 Cellular tumour antigen p53-inducible 5 DUF4544 PF15077.1 EGC36827.1 - 1.2 8.6 9.7 0.23 10.9 4.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4544) Mur_ligase_M PF08245.7 EGC36829.1 - 1.7e-07 31.5 0.0 6.6e-06 26.2 0.0 2.5 1 1 0 1 1 1 1 Mur ligase middle domain Eno-Rase_NADH_b PF12242.3 EGC36829.1 - 0.052 13.3 0.0 0.1 12.4 0.0 1.4 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase CBM49 PF09478.5 EGC36830.1 - 2.7e-14 52.9 2.7 3.8e-14 52.5 1.9 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TILa PF12714.2 EGC36830.1 - 1.6 8.5 8.1 6.9 6.5 0.3 2.3 1 1 1 2 2 2 0 TILa domain BTB PF00651.26 EGC36831.1 - 1.2e-21 76.8 6.9 3e-21 75.4 1.0 3.0 2 1 1 3 3 3 1 BTB/POZ domain BACK PF07707.10 EGC36831.1 - 8.4e-05 22.3 1.6 0.0014 18.4 0.1 2.6 2 1 1 3 3 3 1 BTB And C-terminal Kelch Dymeclin PF09742.4 EGC36832.1 - 5.2e-86 289.2 57.6 8.7e-83 278.6 39.9 3.3 1 1 0 1 1 1 1 Dyggve-Melchior-Clausen syndrome protein Ribosomal_S13 PF00416.17 EGC36833.1 - 0.21 12.0 5.0 0.43 11.0 3.5 1.5 1 0 0 1 1 1 0 Ribosomal protein S13/S18 CobT PF06213.7 EGC36833.1 - 0.29 10.2 9.6 0.31 10.1 6.6 1.1 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT Peptidase_M3 PF01432.15 EGC36834.1 - 5.8e-126 421.1 3.1 5.8e-126 421.1 2.2 2.0 2 0 0 2 2 2 1 Peptidase family M3 DUF3755 PF12579.3 EGC36834.1 - 0.45 9.9 2.9 6.8 6.1 0.2 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF3755) DUF3328 PF11807.3 EGC36835.1 - 0.013 15.2 3.8 0.016 14.9 2.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3328) Shisa PF13908.1 EGC36835.1 - 0.024 14.8 0.9 0.03 14.5 0.6 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator 7TM_GPCR_Srsx PF10320.4 EGC36835.1 - 0.059 12.5 4.5 0.082 12.0 1.0 2.0 2 0 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srsx EphA2_TM PF14575.1 EGC36835.1 - 0.098 13.0 1.2 0.46 10.8 0.3 2.3 1 1 1 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain 60KD_IMP PF02096.15 EGC36835.1 - 0.12 12.0 0.8 0.24 11.0 0.1 1.7 2 0 0 2 2 2 0 60Kd inner membrane protein TMEM51 PF15345.1 EGC36835.1 - 0.18 11.4 1.0 0.3 10.7 0.7 1.5 1 1 0 1 1 1 0 Transmembrane protein 51 YtpI PF14007.1 EGC36835.1 - 0.18 11.7 0.1 0.18 11.7 0.1 2.2 2 1 0 2 2 2 0 YtpI-like protein DUF3357 PF11837.3 EGC36835.1 - 0.21 11.4 6.5 0.32 10.8 1.0 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) DUF202 PF02656.10 EGC36835.1 - 0.25 11.5 14.1 0.21 11.8 2.2 2.9 1 1 1 2 2 2 0 Domain of unknown function (DUF202) 7TMR-DISM_7TM PF07695.6 EGC36835.1 - 0.57 9.8 9.6 2.2 7.9 6.7 1.7 1 1 0 1 1 1 0 7TM diverse intracellular signalling DUF1183 PF06682.7 EGC36835.1 - 2.8 7.4 5.6 3.9 6.9 2.0 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1183) SdpI PF13630.1 EGC36835.1 - 3.2 7.5 7.7 1.8 8.3 1.5 2.4 3 0 0 3 3 3 0 SdpI/YhfL protein family RasGEF PF00617.14 EGC36836.1 - 1.3e-54 184.8 1.4 1.3e-54 184.8 1.0 2.7 2 0 0 2 2 2 1 RasGEF domain GRAM PF02893.15 EGC36836.1 - 2.5e-09 36.5 2.8 3.1e-09 36.2 0.5 2.3 2 0 0 2 2 2 1 GRAM domain RhoGAP PF00620.22 EGC36836.1 - 2.4e-07 30.5 0.1 2.6e-06 27.1 0.1 2.7 2 0 0 2 2 2 1 RhoGAP domain RasGEF_N PF00618.15 EGC36836.1 - 0.0033 17.5 3.1 0.0033 17.5 2.2 5.0 3 1 0 3 3 3 1 RasGEF N-terminal motif WD40 PF00400.27 EGC36837.1 - 0.0026 17.5 10.8 1.9 8.4 0.0 5.0 5 0 0 5 5 5 2 WD domain, G-beta repeat S_locus_glycop PF00954.15 EGC36837.1 - 0.0032 17.7 0.7 0.015 15.5 0.1 2.5 2 0 0 2 2 2 1 S-locus glycoprotein family AMP-binding PF00501.23 EGC36838.1 - 2.9e-77 259.8 0.0 3.4e-77 259.6 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC36838.1 - 5.4e-14 52.8 0.0 8.5e-14 52.2 0.0 1.3 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain GH3 PF03321.8 EGC36838.1 - 0.0021 16.6 0.0 0.025 13.1 0.0 2.1 2 0 0 2 2 2 1 GH3 auxin-responsive promoter Tfb2 PF03849.9 EGC36839.1 - 2e-123 411.6 8.1 2.3e-123 411.4 5.6 1.0 1 0 0 1 1 1 1 Transcription factor Tfb2 Helicase_C_3 PF13625.1 EGC36839.1 - 0.03 14.0 0.0 0.056 13.2 0.0 1.4 1 0 0 1 1 1 0 Helicase conserved C-terminal domain DUF2013 PF09431.5 EGC36839.1 - 0.13 12.0 5.6 0.15 11.7 0.1 3.1 2 1 0 3 3 3 0 Protein of unknown function (DUF2013) NatB_MDM20 PF09797.4 EGC36840.1 - 2.3e-72 243.7 18.4 1.1e-71 241.4 12.8 2.3 1 0 0 1 1 1 1 N-acetyltransferase B complex (NatB) non catalytic subunit TPR_19 PF14559.1 EGC36840.1 - 0.012 15.8 7.1 0.29 11.4 0.1 3.9 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC36840.1 - 0.017 14.8 2.0 0.12 12.2 0.1 3.4 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC36840.1 - 0.025 14.2 3.5 0.65 9.6 0.1 2.9 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 EGC36840.1 - 0.028 14.0 3.1 1.3 8.7 0.2 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC36840.1 - 0.044 14.4 0.1 7.8 7.3 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC36840.1 - 0.11 12.4 1.1 21 5.3 0.1 3.6 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_5 PF12688.2 EGC36840.1 - 0.13 12.3 0.1 0.45 10.5 0.1 1.9 1 0 0 1 1 1 0 Tetratrico peptide repeat Apc3 PF12895.2 EGC36840.1 - 3.2 7.9 17.4 1 9.5 0.3 4.4 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 DASH_Dad2 PF08654.5 EGC36840.1 - 3.2 7.7 9.1 0.85 9.6 0.2 3.7 4 0 0 4 4 4 0 DASH complex subunit Dad2 SpoU_methylase PF00588.14 EGC36841.1 - 3.9e-28 98.1 0.0 1e-27 96.7 0.0 1.8 1 0 0 1 1 1 1 SpoU rRNA Methylase family GTP_EFTU PF00009.22 EGC36842.1 - 2.2e-38 131.5 0.1 4e-38 130.7 0.1 1.4 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain eIF2_C PF09173.6 EGC36842.1 - 3.3e-35 120.0 0.1 8.6e-35 118.6 0.1 1.8 1 0 0 1 1 1 1 Initiation factor eIF2 gamma, C terminal GTP_EFTU_D2 PF03144.20 EGC36842.1 - 5.6e-11 42.3 0.7 1.7e-10 40.8 0.5 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC36842.1 - 0.013 15.4 0.0 0.027 14.4 0.0 1.5 1 0 0 1 1 1 0 50S ribosome-binding GTPase Ribophorin_I PF04597.9 EGC36843.1 - 2.4e-125 418.4 17.1 2.7e-125 418.2 11.9 1.0 1 0 0 1 1 1 1 Ribophorin I Ribosomal_L7Ae PF01248.21 EGC36844.1 - 1.2e-25 88.7 0.0 1.6e-25 88.4 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family RNase_P_pop3 PF08228.6 EGC36844.1 - 0.014 15.1 0.1 0.017 14.9 0.1 1.2 1 0 0 1 1 1 0 RNase P subunit Pop3 PELOTA_1 PF15608.1 EGC36844.1 - 0.027 14.2 0.0 0.036 13.8 0.0 1.2 1 0 0 1 1 1 0 PELOTA RNA binding domain FH2 PF02181.18 EGC36845.1 - 3.1e-72 243.5 29.1 1.7e-68 231.2 6.7 3.6 3 1 0 4 4 4 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EGC36845.1 - 3.8e-47 160.0 9.8 3.8e-47 160.0 6.8 2.8 3 0 0 3 3 3 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGC36845.1 - 8.8e-19 67.6 0.2 8.8e-19 67.6 0.2 3.6 4 1 1 5 5 5 1 Diaphanous FH3 Domain ABC_membrane_3 PF13748.1 EGC36845.1 - 0.002 17.1 0.1 0.0035 16.4 0.0 1.3 1 0 0 1 1 1 1 ABC transporter transmembrane region WD40 PF00400.27 EGC36846.1 - 1.1e-72 237.4 11.7 1.6e-12 46.7 0.3 7.3 7 0 0 7 7 7 7 WD domain, G-beta repeat Tup_N PF08581.5 EGC36846.1 - 6.3e-25 87.1 12.0 6.3e-25 87.1 8.3 1.6 2 0 0 2 2 1 1 Tup N-terminal Cytochrom_D1 PF02239.11 EGC36846.1 - 6e-06 24.8 0.6 0.006 14.9 0.2 2.8 1 1 2 3 3 3 2 Cytochrome D1 heme domain Nbas_N PF15492.1 EGC36846.1 - 1e-05 24.7 0.2 0.23 10.5 0.0 3.6 2 1 2 4 4 4 2 Neuroblastoma-amplified sequence, N terminal Nup160 PF11715.3 EGC36846.1 - 8.9e-05 20.8 0.6 6.1 4.8 0.0 4.4 1 1 3 4 4 4 2 Nucleoporin Nup120/160 PD40 PF07676.7 EGC36846.1 - 9.7e-05 21.9 3.8 5.1 6.8 0.0 5.6 6 0 0 6 6 6 1 WD40-like Beta Propeller Repeat BBP1_C PF15272.1 EGC36846.1 - 0.00015 21.4 7.4 0.00015 21.4 5.2 1.6 2 0 0 2 2 2 1 Spindle pole body component BBP1, C-terminal LXG PF04740.7 EGC36846.1 - 0.0015 18.3 5.8 0.0025 17.6 4.0 1.2 1 0 0 1 1 1 1 LXG domain of WXG superfamily Spc7 PF08317.6 EGC36846.1 - 0.0018 17.0 5.5 0.0018 17.0 3.8 1.5 2 0 0 2 2 2 1 Spc7 kinetochore protein Nucleoporin_N PF08801.6 EGC36846.1 - 0.0022 16.8 0.8 0.57 8.8 0.1 2.5 1 1 0 2 2 2 2 Nup133 N terminal like DUF3312 PF11768.3 EGC36846.1 - 0.0023 16.2 0.0 1.6 6.8 0.0 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF3312) Caenor_Her-1 PF09232.5 EGC36846.1 - 0.085 12.9 0.7 13 5.8 0.1 2.3 2 0 0 2 2 2 0 Caenorhabditis elegans Her-1 DUF3450 PF11932.3 EGC36846.1 - 0.19 10.9 7.6 0.39 9.9 5.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) DUF1180 PF06679.7 EGC36846.1 - 0.52 10.1 2.0 0.84 9.4 1.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1180) Proteasome_A_N PF10584.4 EGC36846.1 - 1.3 8.3 10.1 52 3.2 0.0 5.3 6 0 0 6 6 6 0 Proteasome subunit A N-terminal signature CENP-Q PF13094.1 EGC36846.1 - 3 7.8 15.1 0.49 10.3 5.2 2.1 2 0 0 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit IncA PF04156.9 EGC36846.1 - 7.4 6.1 13.9 0.061 12.9 4.0 1.6 2 0 0 2 2 2 0 IncA protein URO-D PF01208.12 EGC36847.1 - 1.4e-127 425.3 0.0 1.6e-127 425.1 0.0 1.0 1 0 0 1 1 1 1 Uroporphyrinogen decarboxylase (URO-D) Aldedh PF00171.17 EGC36848.1 - 8.9e-78 261.6 0.0 1.1e-77 261.3 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1312 PF07009.6 EGC36848.1 - 0.17 11.7 0.6 0.31 10.8 0.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) OmpW PF03922.9 EGC36850.1 - 0.015 14.9 0.3 3.1 7.4 0.1 2.4 2 0 0 2 2 2 0 OmpW family DUF2702 PF10863.3 EGC36850.1 - 0.044 13.4 3.3 0.87 9.2 0.3 3.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2702) F-box-like PF12937.2 EGC36850.1 - 0.069 12.8 0.0 0.27 11.0 0.0 2.1 2 0 0 2 2 2 0 F-box-like LRR_6 PF13516.1 EGC36850.1 - 0.43 10.7 58.9 2.4 8.4 0.4 12.5 12 1 1 13 13 13 0 Leucine Rich repeat LRR_8 PF13855.1 EGC36850.1 - 4.1 7.2 62.5 0.076 12.7 1.3 8.2 2 2 8 10 10 10 0 Leucine rich repeat YEATS PF03366.11 EGC36851.1 - 2.4e-28 97.6 0.1 4.7e-28 96.7 0.1 1.5 1 0 0 1 1 1 1 YEATS family DUF2360 PF10152.4 EGC36851.1 - 0.013 15.7 3.7 0.024 14.9 2.5 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) Mnd1 PF03962.10 EGC36851.1 - 0.13 11.9 6.0 0.19 11.3 4.2 1.2 1 0 0 1 1 1 0 Mnd1 family APC_CDC26 PF10471.4 EGC36852.1 - 4e-12 46.6 4.7 5.7e-12 46.2 3.2 1.3 1 1 0 1 1 1 1 Anaphase-promoting complex APC subunit 1 LRR_5 PF13306.1 EGC36853.1 - 0.05 13.2 3.0 0.059 13.0 2.1 1.2 1 0 0 1 1 1 0 Leucine rich repeats (6 copies) TIP49 PF06068.8 EGC36854.1 - 9.8e-191 633.6 2.3 1.2e-190 633.4 1.6 1.1 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGC36854.1 - 1e-11 45.1 0.4 1.7e-07 31.4 0.0 2.9 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGC36854.1 - 2.4e-10 39.8 1.4 1.9e-06 27.0 0.0 3.1 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_22 PF13401.1 EGC36854.1 - 2.9e-06 27.4 0.1 0.071 13.2 0.0 2.7 2 1 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC36854.1 - 1.7e-05 24.9 0.0 0.013 15.5 0.0 2.2 2 0 0 2 2 2 2 AAA ATPase domain AAA_5 PF07728.9 EGC36854.1 - 2.8e-05 23.8 0.9 0.006 16.3 0.0 3.0 3 0 0 3 3 3 1 AAA domain (dynein-related subfamily) AAA_19 PF13245.1 EGC36854.1 - 0.00021 20.9 0.0 0.00046 19.8 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain AAA_25 PF13481.1 EGC36854.1 - 0.00037 19.9 0.0 0.00064 19.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGC36854.1 - 0.00061 19.0 0.2 0.03 13.4 0.1 2.4 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_14 PF13173.1 EGC36854.1 - 0.00078 19.3 0.0 1.1 9.1 0.0 2.5 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGC36854.1 - 0.0009 18.7 0.1 0.0021 17.4 0.0 1.6 1 0 0 1 1 1 1 IstB-like ATP binding protein Sigma54_activat PF00158.21 EGC36854.1 - 0.0013 18.2 0.1 0.84 9.0 0.0 2.4 2 0 0 2 2 2 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGC36854.1 - 0.0016 17.6 0.3 0.0034 16.5 0.2 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGC36854.1 - 0.005 17.1 0.0 0.025 14.8 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGC36854.1 - 0.0062 16.5 0.0 0.012 15.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC36854.1 - 0.0087 16.8 0.0 0.021 15.6 0.0 1.8 1 1 0 1 1 1 1 AAA domain DnaB_C PF03796.10 EGC36854.1 - 0.025 13.4 0.0 0.05 12.4 0.0 1.4 1 0 0 1 1 1 0 DnaB-like helicase C terminal domain AAA_33 PF13671.1 EGC36854.1 - 0.064 13.1 0.0 0.17 11.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGC36854.1 - 0.13 11.9 0.0 0.25 11.0 0.0 1.4 1 0 0 1 1 1 0 NACHT domain DTW PF03942.10 EGC36855.1 - 7e-27 93.9 0.0 1.4e-26 92.9 0.0 1.5 1 0 0 1 1 1 1 DTW domain zf-B_box PF00643.19 EGC36855.1 - 0.014 15.2 4.5 0.025 14.4 3.1 1.3 1 0 0 1 1 1 0 B-box zinc finger Rap_GAP PF02145.10 EGC36856.1 - 6.2e-59 198.5 0.3 8.5e-59 198.1 0.2 1.2 1 0 0 1 1 1 1 Rap/ran-GAP PALP PF00291.20 EGC36858.1 - 6.3e-43 147.1 0.0 8.1e-43 146.7 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-phosphate dependent enzyme Wbp11 PF09429.5 EGC36859.1 - 7.7e-11 41.8 18.3 7.7e-11 41.8 12.7 1.9 2 1 0 2 2 2 1 WW domain binding protein 11 NpwBP PF12622.2 EGC36859.1 - 0.00025 21.4 24.4 0.00025 21.4 16.9 5.5 3 3 1 4 4 4 1 mRNA biogenesis factor DUF4348 PF14254.1 EGC36859.1 - 2.7 7.0 12.9 0.035 13.2 3.6 1.8 2 1 0 2 2 2 0 Domain of unknown function (DUF4348) DUF908 PF06012.7 EGC36859.1 - 4.4 6.5 15.3 4.2 6.5 0.4 2.1 2 0 0 2 2 2 0 Domain of Unknown Function (DUF908) NIF PF03031.13 EGC36860.1 - 0.045 13.4 0.2 0.074 12.7 0.1 1.4 1 0 0 1 1 1 0 NLI interacting factor-like phosphatase ELMO_CED12 PF04727.8 EGC36862.1 - 1.2e-39 135.5 0.7 2.5e-39 134.5 0.5 1.5 1 0 0 1 1 1 1 ELMO/CED-12 family Pkinase_Tyr PF07714.12 EGC36864.1 - 3.9e-06 26.1 0.1 5.6e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC36864.1 - 1.2e-05 24.5 0.3 1.7e-05 24.1 0.2 1.2 1 0 0 1 1 1 1 Protein kinase domain Ribosomal_S17e PF00833.13 EGC36864.1 - 0.068 12.9 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 Ribosomal S17 Afi1 PF07792.7 EGC36865.1 - 9.3 6.2 0.0 9.3 6.2 0.0 3.7 3 1 1 4 4 4 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DUF21 PF01595.15 EGC36866.1 - 1.4e-33 115.7 3.7 2.1e-33 115.1 2.6 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF21 CBS PF00571.23 EGC36866.1 - 0.00011 21.9 0.1 0.63 9.8 0.0 2.5 2 0 0 2 2 2 2 CBS domain Halogen_Hydrol PF10112.4 EGC36866.1 - 0.031 13.7 1.1 0.059 12.7 0.0 1.9 1 1 1 2 2 2 0 5-bromo-4-chloroindolyl phosphate hydrolysis protein WD40 PF00400.27 EGC36867.1 - 9.3e-47 155.3 22.9 1.2e-08 34.4 0.0 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGC36867.1 - 0.0027 17.4 3.4 0.01 15.5 1.5 2.1 1 1 1 2 2 2 1 Transcription factor IIIC subunit delta N-term zf-HIT PF04438.11 EGC36868.1 - 7.2e-10 38.3 10.7 1.3e-09 37.4 7.4 1.5 1 0 0 1 1 1 1 HIT zinc finger zf-C2H2_6 PF13912.1 EGC36868.1 - 0.69 9.9 10.0 6.2 6.8 2.0 2.7 2 0 0 2 2 2 0 C2H2-type zinc finger Peptidase_C39_2 PF13529.1 EGC36869.1 - 1.7e-05 25.2 1.4 9.5e-05 22.7 0.0 2.6 1 1 0 2 2 2 1 Peptidase_C39 like family DBD_Tnp_Hermes PF10683.4 EGC36869.1 - 0.064 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain TAXi_C PF14541.1 EGC36870.1 - 3.1e-13 49.5 1.2 3.8e-13 49.3 0.1 1.7 2 0 0 2 2 2 1 Xylanase inhibitor C-terminal TSP_1 PF00090.14 EGC36870.1 - 0.0079 16.2 3.4 0.0079 16.2 2.4 4.3 5 1 0 5 5 5 2 Thrombospondin type 1 domain FNIP PF05725.7 EGC36871.1 - 6.3e-41 138.0 59.4 6.9e-10 38.7 1.3 9.4 3 2 8 12 12 12 10 FNIP Repeat Med31 PF05669.7 EGC36871.1 - 0.15 11.8 6.5 0.31 10.8 4.2 1.7 1 1 0 1 1 1 0 SOH1 YtxC PF08812.6 EGC36873.1 - 0.068 12.6 1.1 0.098 12.1 0.8 1.2 1 0 0 1 1 1 0 YtxC-like family Ofd1_CTDD PF10637.4 EGC36873.1 - 0.088 11.9 0.8 0.13 11.3 0.6 1.1 1 0 0 1 1 1 0 Oxoglutarate and iron-dependent oxygenase degradation C-term Antimicrobial_7 PF08102.6 EGC36873.1 - 0.29 11.1 1.2 0.6 10.1 0.1 1.9 2 0 0 2 2 2 0 Scorpion antimicrobial peptide Sedlin_N PF04628.8 EGC36874.1 - 1.5e-36 125.2 0.5 1.6e-36 125.0 0.3 1.0 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region Sybindin PF04099.7 EGC36874.1 - 8e-06 25.6 0.4 9e-06 25.4 0.3 1.1 1 0 0 1 1 1 1 Sybindin-like family Dus PF01207.12 EGC36875.1 - 1.6e-55 188.1 0.0 2.5e-55 187.4 0.0 1.3 1 0 0 1 1 1 1 Dihydrouridine synthase (Dus) zf-CCCH PF00642.19 EGC36875.1 - 0.00044 19.8 9.4 0.018 14.7 0.2 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Asp-B-Hydro_N PF05279.6 EGC36875.1 - 0.1 12.4 10.9 0.15 11.8 7.6 1.2 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region zf-CCCH_2 PF14608.1 EGC36875.1 - 1.1 9.4 10.5 0.87 9.6 1.2 2.7 2 0 0 2 2 2 0 Zinc finger C-x8-C-x5-C-x3-H type zf-CCHH PF10283.4 EGC36875.1 - 2.9 7.7 10.9 2.2 8.1 1.2 2.7 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif Ndc1_Nup PF09531.5 EGC36875.1 - 4 5.7 6.7 5.3 5.3 4.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Neur_chan_memb PF02932.11 EGC36875.1 - 4.6 7.0 5.3 7.4 6.3 3.7 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Atrophin-1 PF03154.10 EGC36875.1 - 4.8 5.1 12.6 6.7 4.7 8.8 1.1 1 0 0 1 1 1 0 Atrophin-1 family Ycf1 PF05758.7 EGC36875.1 - 6.4 4.3 13.0 8.6 3.9 9.0 1.1 1 0 0 1 1 1 0 Ycf1 Sporozoite_P67 PF05642.6 EGC36875.1 - 7.1 4.3 11.5 11 3.6 8.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen PARP PF00644.15 EGC36876.1 - 1.7e-64 217.0 0.0 1.7e-64 217.0 0.0 2.8 2 1 0 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC36876.1 - 2.9e-43 146.7 4.7 6.8e-43 145.5 3.3 1.7 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGC36876.1 - 4.4e-20 71.4 2.0 1.2e-19 70.0 1.4 1.8 1 0 0 1 1 1 1 WGR domain BRCT PF00533.21 EGC36876.1 - 1.9e-13 50.3 3.3 2.3e-13 50.1 0.8 2.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC36876.1 - 4.5e-05 23.2 0.2 8.4e-05 22.3 0.1 1.5 1 0 0 1 1 1 1 twin BRCT domain TFIIF_alpha PF05793.7 EGC36876.1 - 0.14 10.4 32.1 0.0052 15.2 18.1 1.6 2 0 0 2 2 2 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pap_E4 PF02711.9 EGC36876.1 - 3.5 8.5 6.7 2.8 8.8 2.9 2.2 2 0 0 2 2 2 0 E4 protein LMBR1 PF04791.11 EGC36876.1 - 3.9 5.9 5.8 1.1 7.7 2.0 1.5 1 1 0 1 1 1 0 LMBR1-like membrane protein Peptidase_A22B PF04258.8 EGC36877.1 - 2.8e-81 273.2 12.0 3.7e-81 272.8 8.3 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1119 PF06550.6 EGC36877.1 - 8.4e-05 21.8 10.6 0.00061 19.0 7.2 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1119) FNIP PF05725.7 EGC36878.1 - 5.8e-66 218.2 72.5 9.9e-15 54.2 1.8 10.0 1 1 9 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 EGC36878.1 - 0.0013 18.6 4.3 27 4.8 0.0 6.2 7 1 1 8 8 8 2 Protein of unknown function (DUF1769) TFIID-18kDa PF02269.11 EGC36879.1 - 7.7e-32 108.9 1.5 9e-32 108.7 1.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 18kD subunit CBFD_NFYB_HMF PF00808.18 EGC36879.1 - 0.02 14.9 0.0 0.054 13.5 0.0 1.7 2 0 0 2 2 2 0 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC36879.1 - 0.086 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Bromodomain associated CENP-S PF15630.1 EGC36879.1 - 0.087 13.0 0.0 0.2 11.8 0.0 1.6 1 0 0 1 1 1 0 Kinetochore component CENP-S DUF202 PF02656.10 EGC36880.1 - 0.00085 19.4 2.3 0.00085 19.4 1.6 1.8 1 1 1 2 2 2 1 Domain of unknown function (DUF202) bZIP_1 PF00170.16 EGC36881.1 - 0.89 9.5 9.2 1.3 9.0 2.1 3.2 2 0 0 2 2 2 0 bZIP transcription factor Pkinase PF00069.20 EGC36882.1 - 2.9e-12 46.2 0.3 4.2e-12 45.7 0.2 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36882.1 - 3e-08 33.0 0.1 4.5e-08 32.4 0.1 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGC36882.1 - 4e-05 23.0 0.4 7.5e-05 22.1 0.3 1.4 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC36882.1 - 0.00043 20.0 0.1 0.00069 19.4 0.1 1.3 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC36882.1 - 0.0036 16.1 0.3 0.0062 15.4 0.2 1.3 1 0 0 1 1 1 1 Seadornavirus VP7 Kdo PF06293.9 EGC36882.1 - 0.013 14.5 0.1 0.023 13.7 0.1 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Choline_kinase PF01633.15 EGC36882.1 - 0.017 14.7 1.4 0.035 13.6 0.9 1.5 1 0 0 1 1 1 0 Choline/ethanolamine kinase Kinase-like PF14531.1 EGC36882.1 - 0.04 12.8 0.0 0.062 12.2 0.0 1.2 1 0 0 1 1 1 0 Kinase-like OrfB_Zn_ribbon PF07282.6 EGC36882.1 - 1.4 8.6 7.3 0.74 9.5 3.4 1.8 2 0 0 2 2 2 0 Putative transposase DNA-binding domain Mcm10 PF09332.6 EGC36882.1 - 4.5 6.5 7.0 8.9 5.5 4.9 1.4 1 0 0 1 1 1 0 Mcm10 replication factor FH2 PF02181.18 EGC36883.1 - 5.1e-90 302.0 22.2 7.4e-89 298.2 8.4 2.7 2 0 0 2 2 2 2 Formin Homology 2 Domain Drf_GBD PF06371.8 EGC36883.1 - 5e-44 149.9 0.5 5e-44 149.9 0.3 4.3 4 0 0 4 4 4 1 Diaphanous GTPase-binding Domain Drf_FH3 PF06367.11 EGC36883.1 - 4.7e-38 130.5 0.9 4.7e-38 130.5 0.6 3.9 2 2 2 4 4 4 1 Diaphanous FH3 Domain C2 PF00168.25 EGC36883.1 - 1.7e-11 43.7 0.2 4.6e-11 42.4 0.1 1.7 1 0 0 1 1 1 1 C2 domain ADIP PF11559.3 EGC36883.1 - 0.0032 17.3 9.2 0.0032 17.3 6.4 3.6 5 0 0 5 5 5 1 Afadin- and alpha -actinin-Binding AsnC_trans_reg PF01037.16 EGC36883.1 - 0.037 13.7 0.1 0.17 11.5 0.0 2.2 1 0 0 1 1 1 0 AsnC family Gag_spuma PF03276.9 EGC36883.1 - 4.9 5.3 21.1 7.8 4.6 14.6 1.2 1 0 0 1 1 1 0 Spumavirus gag protein Med17 PF10156.4 EGC36884.1 - 3e-06 25.8 24.2 6.9e-06 24.5 6.0 4.0 2 1 0 2 2 2 1 Subunit 17 of Mediator complex DUF4447 PF14590.1 EGC36884.1 - 0.066 12.8 1.0 0.13 11.8 0.7 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4447) CobT PF06213.7 EGC36884.1 - 3.6 6.6 18.8 0.98 8.4 10.5 1.8 2 0 0 2 2 2 0 Cobalamin biosynthesis protein CobT Stk19 PF10494.4 EGC36885.1 - 1.6e-29 103.0 6.0 1.6e-29 103.0 4.1 1.5 2 0 0 2 2 2 1 Serine-threonine protein kinase 19 p450 PF00067.17 EGC36886.1 - 4e-79 266.2 0.0 7.1e-79 265.4 0.0 1.4 1 0 0 1 1 1 1 Cytochrome P450 Trs65 PF12735.2 EGC36886.1 - 4.8e-08 32.6 25.5 2.9e-07 30.0 12.0 5.6 3 2 1 4 4 4 2 TRAPP trafficking subunit Trs65 Cornichon PF03311.9 EGC36887.1 - 1.1e-30 106.3 8.8 1.4e-30 106.0 6.1 1.0 1 0 0 1 1 1 1 Cornichon protein PUF PF00806.14 EGC36888.1 - 1.7e-70 228.6 24.2 2.8e-10 39.0 0.6 8.2 8 0 0 8 8 8 8 Pumilio-family RNA binding repeat DNA_pol3_delta2 PF13177.1 EGC36888.1 - 0.014 15.0 0.7 0.031 13.9 0.5 1.7 1 1 0 1 1 1 0 DNA polymerase III, delta subunit DUF3244 PF11589.3 EGC36888.1 - 0.028 14.1 0.3 0.085 12.5 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) MIF4G PF02854.14 EGC36888.1 - 0.42 10.0 5.3 0.64 9.3 0.5 2.9 2 1 1 3 3 3 0 MIF4G domain Ribosomal_S10 PF00338.17 EGC36889.1 - 4.6e-21 74.4 0.1 5.4e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e FNIP PF05725.7 EGC36890.1 - 3.8e-05 23.5 45.9 0.019 14.9 0.0 8.9 7 3 2 10 10 10 7 FNIP Repeat LRR_4 PF12799.2 EGC36890.1 - 0.19 11.3 0.1 0.19 11.3 0.1 7.0 7 2 2 9 9 9 0 Leucine Rich repeats (2 copies) Cob_adeno_trans PF01923.13 EGC36892.1 - 0.0012 18.7 0.2 0.0021 17.8 0.1 1.4 1 0 0 1 1 1 1 Cobalamin adenosyltransferase DUF596 PF04591.7 EGC36892.1 - 0.011 15.6 0.1 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF596 Fib_alpha PF08702.5 EGC36892.1 - 0.74 9.9 12.2 2.3 8.3 8.5 1.8 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNase_PH PF01138.16 EGC36893.1 - 1.8e-25 89.7 0.0 3e-25 89.0 0.0 1.4 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGC36893.1 - 1.4e-14 53.7 0.0 2.7e-14 52.8 0.0 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 HCaRG PF07258.9 EGC36894.1 - 3.3e-22 78.8 2.1 3.9e-22 78.6 1.5 1.1 1 0 0 1 1 1 1 HCaRG protein RIH_assoc PF08454.6 EGC36894.1 - 2.5 7.7 6.2 1 8.9 1.1 2.2 2 1 0 2 2 2 0 RyR and IP3R Homology associated MCM PF00493.18 EGC36895.1 - 5.8e-134 446.0 0.4 8.5e-134 445.5 0.3 1.2 1 0 0 1 1 1 1 MCM2/3/5 family MCM_N PF14551.1 EGC36895.1 - 5.9e-20 71.9 1.3 1.7e-19 70.4 0.9 1.9 1 0 0 1 1 1 1 MCM N-terminal domain Mg_chelatase PF01078.16 EGC36895.1 - 3.4e-06 26.3 0.0 0.0013 17.9 0.0 2.4 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC36895.1 - 9.5e-06 25.3 0.0 2.3e-05 24.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC36895.1 - 0.0027 17.3 0.0 0.0077 15.8 0.0 1.8 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Sigma54_activat PF00158.21 EGC36895.1 - 0.014 14.8 0.1 0.17 11.3 0.0 2.2 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA PF00004.24 EGC36895.1 - 0.032 14.4 2.2 4.8 7.3 0.0 2.9 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) zf-NADH-PPase PF09297.6 EGC36895.1 - 1.1 8.8 3.2 0.46 10.0 0.3 1.9 2 0 0 2 2 2 0 NADH pyrophosphatase zinc ribbon domain Pro_isomerase PF00160.16 EGC36897.1 - 4.6e-51 173.0 0.1 1e-50 171.9 0.0 1.6 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD Rtf2 PF04641.7 EGC36897.1 - 3.5e-07 29.6 18.4 3.5e-07 29.6 12.8 3.3 2 1 0 2 2 2 1 Rtf2 RING-finger U-box PF04564.10 EGC36897.1 - 0.0017 18.2 1.0 0.0098 15.8 0.0 2.9 3 1 1 4 4 4 1 U-box domain zf-Nse PF11789.3 EGC36897.1 - 0.0031 17.0 0.5 0.017 14.6 0.1 2.4 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit Glyco_hydro_77 PF02446.12 EGC36898.1 - 3.8e-158 527.1 3.9 4.7e-158 526.8 2.7 1.1 1 0 0 1 1 1 1 4-alpha-glucanotransferase CBM_20 PF00686.14 EGC36898.1 - 1.7e-39 133.2 5.7 9.6e-20 69.9 0.4 2.6 2 0 0 2 2 2 2 Starch binding domain DUF3395 PF11875.3 EGC36899.1 - 1.2e-40 138.6 2.7 2e-40 137.8 1.9 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3395) DnaJ PF00226.26 EGC36899.1 - 4.9e-21 74.2 1.4 1.2e-20 72.9 1.0 1.7 1 0 0 1 1 1 1 DnaJ domain 7tm_1 PF00001.16 EGC36899.1 - 0.057 12.5 0.1 0.091 11.8 0.0 1.3 1 0 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) SAP PF02037.22 EGC36900.1 - 2.9e-05 23.4 4.5 4e-05 22.9 1.5 2.3 2 0 0 2 2 2 1 SAP domain HeH PF12949.2 EGC36900.1 - 3.3e-05 23.3 0.0 8.3e-05 22.0 0.0 1.7 1 0 0 1 1 1 1 HeH/LEM domain Pyrophosphatase PF00719.14 EGC36901.1 - 1.4e-50 170.7 0.1 1.7e-50 170.5 0.1 1.1 1 0 0 1 1 1 1 Inorganic pyrophosphatase BSD PF03909.12 EGC36902.1 - 4.6e-07 29.4 0.3 2.2e-06 27.2 0.2 2.2 1 0 0 1 1 1 1 BSD domain IBR PF01485.16 EGC36903.1 - 0.00013 21.7 7.7 0.00013 21.7 5.3 4.3 3 1 1 4 4 4 1 IBR domain zf-RING_2 PF13639.1 EGC36903.1 - 0.00023 20.9 10.2 0.00023 20.9 7.1 3.3 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGC36903.1 - 0.00098 18.7 10.6 0.00098 18.7 7.3 3.5 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC36903.1 - 0.0012 18.8 11.3 0.0012 18.8 7.8 3.6 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC36903.1 - 0.01 15.5 9.6 0.01 15.5 6.6 3.3 3 1 0 3 3 3 0 zinc-RING finger domain TRL PF13146.1 EGC36903.1 - 0.2 11.6 1.8 0.94 9.5 0.2 2.4 2 0 0 2 2 2 0 TRL-like protein family C1_4 PF07975.7 EGC36903.1 - 0.85 9.6 23.3 0.14 12.1 5.4 3.5 2 1 1 3 3 3 0 TFIIH C1-like domain Myb_DNA-binding PF00249.26 EGC36904.1 - 1.6e-33 114.4 4.9 7.7e-17 61.0 0.2 2.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC36904.1 - 8.4e-29 99.4 5.1 6e-18 64.7 0.3 2.0 1 1 1 2 2 2 2 Myb-like DNA-binding domain SLIDE PF09111.5 EGC36904.1 - 0.0055 16.4 0.1 2.2 8.0 0.0 2.2 1 1 1 2 2 2 2 SLIDE Myb_DNA-bind_5 PF13873.1 EGC36904.1 - 0.008 16.0 4.6 13 5.7 0.1 4.0 1 1 3 4 4 4 1 Myb/SANT-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGC36904.1 - 0.031 14.3 6.4 1 9.5 1.6 3.3 1 1 1 2 2 2 0 Myb/SANT-like DNA-binding domain CENP-S PF15630.1 EGC36905.1 - 4.2e-25 87.7 0.6 4.2e-25 87.7 0.4 1.8 2 0 0 2 2 2 1 Kinetochore component CENP-S TFIID-31kDa PF02291.10 EGC36905.1 - 0.0057 16.4 0.1 0.013 15.2 0.0 1.6 1 1 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EGC36905.1 - 0.015 14.5 0.0 0.015 14.5 0.0 2.3 2 1 0 2 2 2 0 Centromere kinetochore component CENP-T Histone PF00125.19 EGC36905.1 - 0.051 13.6 0.1 0.099 12.7 0.1 1.4 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 Erf4 PF10256.4 EGC36906.1 - 1.2e-14 54.1 1.6 4.1e-06 26.6 0.1 2.3 2 0 0 2 2 2 2 Golgin subfamily A member 7/ERF4 family DUF4381 PF14316.1 EGC36906.1 - 0.035 14.2 0.4 7.5 6.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4381) DUF2681 PF10883.3 EGC36906.1 - 0.17 12.0 0.2 15 5.8 0.0 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) Vpu PF00558.14 EGC36906.1 - 0.37 10.3 5.1 3.6 7.1 0.1 2.4 2 0 0 2 2 2 0 Vpu protein DER1 PF04511.10 EGC36907.1 - 1.4e-53 181.3 16.9 1.6e-53 181.1 11.7 1.0 1 0 0 1 1 1 1 Der1-like family DUF1331 PF07048.6 EGC36907.1 - 0.02 14.3 0.1 0.076 12.4 0.1 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1331) DUF4133 PF13571.1 EGC36907.1 - 0.78 10.0 4.5 0.17 12.1 0.4 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4133) Glyco_hydro_9 PF00759.14 EGC36908.1 - 7.7e-139 463.4 2.9 8.7e-139 463.2 2.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 PTR2 PF00854.16 EGC36909.1 - 5.4e-71 239.3 8.9 1.7e-68 231.0 4.3 2.2 1 1 1 2 2 2 2 POT family CbiM PF01891.11 EGC36909.1 - 0.017 14.7 0.1 0.017 14.7 0.1 3.0 3 0 0 3 3 3 0 Cobalt uptake substrate-specific transmembrane region Mob_synth_C PF06463.8 EGC36910.1 - 8.7e-39 132.1 0.0 2.2e-38 130.8 0.0 1.7 1 0 0 1 1 1 1 Molybdenum Cofactor Synthesis C Radical_SAM PF04055.16 EGC36910.1 - 6.1e-25 88.3 0.3 1.1e-24 87.4 0.2 1.5 1 0 0 1 1 1 1 Radical SAM superfamily Fer4_12 PF13353.1 EGC36910.1 - 3.6e-08 33.6 1.2 7e-08 32.6 0.1 2.0 2 1 1 3 3 3 1 4Fe-4S single cluster domain Fer4_14 PF13394.1 EGC36910.1 - 2.3e-07 30.8 0.0 2.3e-07 30.8 0.0 2.5 4 0 0 4 4 4 1 4Fe-4S single cluster domain AhpC-TSA PF00578.16 EGC36910.1 - 0.067 12.8 0.0 8 6.1 0.0 2.9 2 1 1 3 3 3 0 AhpC/TSA family MoaC PF01967.16 EGC36911.1 - 5.7e-45 152.3 2.9 2.4e-44 150.3 2.0 1.7 1 1 0 1 1 1 1 MoaC family GATA PF00320.22 EGC36912.1 - 4.9e-17 60.9 3.8 1.3e-16 59.5 2.6 1.8 1 0 0 1 1 1 1 GATA zinc finger Glyoxalase PF00903.20 EGC36913.1 - 1.4e-21 76.8 0.0 1.6e-21 76.6 0.0 1.0 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGC36913.1 - 7.6e-16 58.6 0.0 8.8e-16 58.4 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_4 PF13669.1 EGC36913.1 - 5.6e-10 39.1 0.0 3.3e-09 36.7 0.0 1.8 1 1 1 2 2 2 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily CppA_N PF14506.1 EGC36913.1 - 0.018 14.7 0.0 0.024 14.3 0.0 1.3 1 0 0 1 1 1 0 CppA N-terminal Peptidase_M17_N PF02789.12 EGC36913.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.3 1 0 0 1 1 1 0 Cytosol aminopeptidase family, N-terminal domain RhoGAP PF00620.22 EGC36914.1 - 8.9e-30 103.3 0.0 8.9e-30 103.3 0.0 2.6 3 1 0 3 3 3 1 RhoGAP domain DUF1479 PF07350.7 EGC36916.1 - 2.1e-13 49.5 0.6 1.1e-08 33.9 0.1 2.1 2 0 0 2 2 2 2 Protein of unknown function (DUF1479) PhyH PF05721.8 EGC36916.1 - 2.3e-05 24.5 0.1 0.0069 16.4 0.0 2.2 2 0 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) HSP20 PF00011.16 EGC36917.1 - 6.8e-15 54.7 3.7 2e-07 30.7 0.1 2.4 1 1 1 2 2 2 2 Hsp20/alpha crystallin family HD-ZIP_N PF04618.7 EGC36917.1 - 0.33 11.4 3.7 0.72 10.4 0.2 2.2 2 0 0 2 2 2 0 HD-ZIP protein N terminus ACR_tran PF00873.14 EGC36917.1 - 2.3 5.5 4.7 2.6 5.3 3.2 1.1 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family Phage_lysis PF03245.8 EGC36917.1 - 5.1 7.1 8.8 0.83 9.6 1.8 2.2 2 0 0 2 2 2 0 Bacteriophage Rz lysis protein Diphthamide_syn PF01866.12 EGC36918.1 - 4.5e-114 380.8 0.0 5.8e-114 380.4 0.0 1.1 1 0 0 1 1 1 1 Putative diphthamide synthesis protein CBM49 PF09478.5 EGC36919.1 - 6.8e-13 48.5 0.7 1.1e-12 47.8 0.5 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 eIF2A PF08662.6 EGC36920.1 - 1.3e-65 220.7 1.3 6.4e-64 215.2 0.0 2.6 2 1 0 2 2 2 2 Eukaryotic translation initiation factor eIF2A SelR PF01641.13 EGC36920.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.6 1 0 0 1 1 1 0 SelR domain DUF605 PF04652.11 EGC36920.1 - 7.3 5.8 14.3 12 5.2 9.9 1.2 1 0 0 1 1 1 0 Vta1 like RCC1 PF00415.13 EGC36921.1 - 2.9e-56 187.4 5.2 2.1e-12 47.0 0.0 7.9 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC36921.1 - 9.8e-33 111.0 13.6 1e-06 28.1 0.3 7.0 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Exo_endo_phos PF03372.18 EGC36921.1 - 2.2e-31 109.6 0.0 3.6e-31 108.9 0.0 1.3 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family STT3 PF02516.9 EGC36923.1 - 1.2e-116 390.6 42.0 3e-116 389.2 29.1 1.6 1 1 0 1 1 1 1 Oligosaccharyl transferase STT3 subunit PMT_2 PF13231.1 EGC36923.1 - 1.7e-05 24.7 14.7 1.7e-05 24.7 10.2 3.3 4 0 0 4 4 4 1 Dolichyl-phosphate-mannose-protein mannosyltransferase SNF2_N PF00176.18 EGC36924.1 - 7.5e-78 261.3 0.2 7.5e-78 261.3 0.1 2.1 2 0 0 2 2 2 1 SNF2 family N-terminal domain Helicase_C PF00271.26 EGC36924.1 - 2.7e-16 59.2 0.0 1.5e-12 47.1 0.0 4.4 4 0 0 4 4 4 2 Helicase conserved C-terminal domain QLQ PF08880.6 EGC36924.1 - 6.9e-06 25.3 0.3 6.9e-06 25.3 0.2 2.3 2 0 0 2 2 2 1 QLQ C1_1 PF00130.17 EGC36925.1 - 0.0076 15.9 4.8 0.0076 15.9 3.3 1.7 2 0 0 2 2 2 1 Phorbol esters/diacylglycerol binding domain (C1 domain) LIM PF00412.17 EGC36925.1 - 6.1 6.9 14.5 0.067 13.2 4.2 2.1 2 1 0 2 2 2 0 LIM domain ThiS PF02597.15 EGC36926.1 - 6.3e-14 52.1 0.0 7.5e-14 51.9 0.0 1.1 1 0 0 1 1 1 1 ThiS family CBM49 PF09478.5 EGC36927.1 - 2.7e-15 56.2 0.3 3.8e-15 55.7 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Oxysterol_BP PF01237.13 EGC36929.1 - 8.6e-68 228.3 9.1 1.3e-67 227.8 6.3 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein FNIP PF05725.7 EGC36930.1 - 1.7e-11 43.8 89.4 0.022 14.6 0.2 13.3 9 4 2 11 11 11 10 FNIP Repeat zf-TRAF PF02176.13 EGC36932.1 - 5.8e-14 52.2 25.5 3.3e-10 40.1 9.1 4.8 2 1 3 5 5 5 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 EGC36932.1 - 4e-07 29.5 11.7 4e-07 29.5 8.1 3.5 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC36932.1 - 2.6e-06 27.2 9.3 0.00044 19.9 1.5 3.6 1 1 3 4 4 4 2 Seven in absentia protein family zf-C3HC4_2 PF13923.1 EGC36932.1 - 0.00011 22.1 14.1 0.00011 22.1 9.8 4.3 4 2 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC36932.1 - 0.0022 17.7 12.0 0.0022 17.7 8.3 3.4 3 1 0 3 3 3 1 Ring finger domain zf-HYPF PF07503.7 EGC36932.1 - 0.088 12.2 0.2 0.088 12.2 0.2 2.8 3 0 0 3 3 3 0 HypF finger FNIP PF05725.7 EGC36933.1 - 0.001 18.9 0.6 0.001 18.9 0.4 9.5 9 2 0 9 9 9 5 FNIP Repeat FNIP PF05725.7 EGC36934.1 - 7.3e-19 67.4 32.1 6.8e-09 35.5 0.2 9.2 5 3 3 8 8 8 6 FNIP Repeat Recep_L_domain PF01030.19 EGC36934.1 - 0.0035 17.2 0.4 0.0035 17.2 0.3 3.4 3 1 0 3 3 3 1 Receptor L domain DUF1154 PF06631.6 EGC36934.1 - 0.0095 15.5 0.2 0.4 10.3 0.0 3.0 2 0 0 2 2 2 1 Protein of unknown function (DUF1154) HSP20 PF00011.16 EGC36935.1 - 4.7e-16 58.5 0.3 8.9e-16 57.6 0.2 1.4 1 1 0 1 1 1 1 Hsp20/alpha crystallin family DUF3826 PF12875.2 EGC36935.1 - 0.024 14.3 0.5 0.035 13.7 0.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3826) DUF2807 PF10988.3 EGC36935.1 - 0.17 11.3 3.7 2.2 7.7 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2807) Cyclin PF08613.6 EGC36936.1 - 1.5e-31 109.8 0.4 1.5e-31 109.8 0.2 2.9 2 1 0 2 2 2 1 Cyclin Cyclin_N PF00134.18 EGC36936.1 - 1.9e-09 37.1 0.0 3.5e-09 36.2 0.0 1.4 1 0 0 1 1 1 1 Cyclin, N-terminal domain DUF1908 PF08926.6 EGC36936.1 - 2.3 6.9 12.7 2.3 6.8 7.9 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF1908) EB PF01683.13 EGC36937.1 - 0.014 15.4 9.2 0.014 15.4 6.4 7.2 1 1 4 5 5 5 0 EB module Methyltransf_2 PF00891.13 EGC36938.1 - 7.8e-46 156.2 0.0 1.1e-45 155.7 0.0 1.2 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGC36938.1 - 1.3e-05 25.0 0.0 2.7e-05 23.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EGC36938.1 - 0.094 11.9 0.1 0.26 10.5 0.1 1.7 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Methyltransf_2 PF00891.13 EGC36939.1 - 8e-29 100.5 0.0 5.9e-14 51.8 0.0 2.1 2 0 0 2 2 2 2 O-methyltransferase Methyltransf_23 PF13489.1 EGC36939.1 - 0.0066 16.1 0.2 0.048 13.3 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain DUF2855 PF11017.3 EGC36939.1 - 0.014 14.5 0.0 0.022 13.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2855) Phage_T7_Capsid PF05396.6 EGC36939.1 - 0.054 13.6 0.0 0.14 12.2 0.0 1.7 2 0 0 2 2 2 0 Phage T7 capsid assembly protein KBP_C PF12309.3 EGC36940.1 - 3e-40 138.3 22.3 3.8e-39 134.7 11.5 3.2 2 2 0 2 2 2 1 KIF-1 binding protein C terminal TPR_12 PF13424.1 EGC36940.1 - 4.2e-05 23.3 3.4 0.072 13.0 0.0 3.6 4 0 0 4 4 4 2 Tetratricopeptide repeat DUF496 PF04363.7 EGC36940.1 - 0.063 13.0 0.3 0.063 13.0 0.2 3.7 4 1 0 4 4 4 0 Protein of unknown function (DUF496) TPR_6 PF13174.1 EGC36940.1 - 0.1 13.1 0.0 47 4.7 0.0 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC36940.1 - 3.9 7.4 7.3 7.6 6.5 0.0 4.5 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF3184 PF11380.3 EGC36941.1 - 1.5e-11 42.9 2.3 0.008 14.1 0.9 3.3 1 1 2 3 3 3 3 Protein of unknown function (DUF3184) NUC194 PF08163.7 EGC36942.1 - 2.1e-131 438.4 5.6 1.5e-130 435.6 3.9 2.6 1 0 0 1 1 1 1 NUC194 domain PI3_PI4_kinase PF00454.22 EGC36942.1 - 7.3e-49 166.3 0.8 1.8e-47 161.7 0.1 3.0 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EGC36942.1 - 4.4e-15 55.5 15.7 1.6e-13 50.4 9.7 3.7 2 1 0 2 2 2 1 FAT domain FATC PF02260.15 EGC36942.1 - 7.4e-10 38.0 0.8 1.7e-09 36.9 0.1 2.0 2 0 0 2 2 2 1 FATC domain Peptidase_C1 PF00112.18 EGC36943.1 - 1.4e-64 218.0 0.2 1.8e-64 217.6 0.1 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC36943.1 - 3.4e-10 40.0 7.8 3.4e-10 40.0 5.4 2.1 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C39_2 PF13529.1 EGC36943.1 - 0.016 15.5 0.7 0.033 14.5 0.1 1.9 2 0 0 2 2 2 0 Peptidase_C39 like family DUF4365 PF14280.1 EGC36943.1 - 0.019 14.6 0.0 0.039 13.6 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4365) DHO_dh PF01180.16 EGC36944.1 - 6.3e-19 68.0 0.1 8.7e-17 61.0 0.2 2.0 2 0 0 2 2 2 2 Dihydroorotate dehydrogenase Dus PF01207.12 EGC36944.1 - 1e-06 27.8 0.1 0.00096 18.0 0.0 2.1 2 0 0 2 2 2 2 Dihydrouridine synthase (Dus) p450 PF00067.17 EGC36945.1 - 4.8e-95 318.7 0.0 5.5e-95 318.5 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Dicty_spore_N PF04562.7 EGC36946.1 - 2e-09 37.7 22.4 2e-09 37.7 15.5 4.8 3 1 1 5 5 5 2 Dictyostelium spore coat protein, N terminus Pkinase PF00069.20 EGC36947.1 - 2.5e-36 125.1 2.1 3.4e-36 124.7 1.5 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC36947.1 - 9.3e-20 70.7 0.2 1.5e-19 70.0 0.2 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC36947.1 - 0.00031 20.5 0.3 0.0006 19.6 0.2 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC36947.1 - 0.00083 18.4 1.0 0.0038 16.3 0.1 2.0 2 0 0 2 2 2 1 Lipopolysaccharide kinase (Kdo/WaaP) family RIO1 PF01163.17 EGC36947.1 - 0.0098 15.2 0.3 0.019 14.3 0.2 1.4 1 0 0 1 1 1 1 RIO1 family SLBP_RNA_bind PF15247.1 EGC36948.1 - 4.4e-32 109.6 3.3 1.8e-31 107.7 2.3 2.0 1 0 0 1 1 1 1 Histone RNA hairpin-binding protein RNA-binding domain RCC1 PF00415.13 EGC36949.1 - 1.5e-79 261.9 14.4 1.2e-13 51.0 0.1 8.2 8 0 0 8 8 8 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC36949.1 - 3.1e-37 125.4 33.1 1e-07 31.3 0.6 8.1 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGC36949.1 - 8e-24 83.7 7.0 3.5e-14 52.7 0.7 3.3 3 0 0 3 3 3 2 BTB/POZ domain Metallophos_2 PF12850.2 EGC36949.1 - 0.00054 19.8 0.9 0.044 13.6 0.1 3.1 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain Adap_comp_sub PF00928.16 EGC36950.1 - 6.5e-60 202.4 5.3 8.9e-60 201.9 3.7 1.2 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGC36950.1 - 1.2e-06 28.2 1.7 2.3e-06 27.4 1.2 1.4 1 0 0 1 1 1 1 Clathrin adaptor complex small chain PHAT PF09246.5 EGC36950.1 - 0.012 15.1 0.0 0.026 14.1 0.0 1.5 1 0 0 1 1 1 0 PHAT Porin_3 PF01459.17 EGC36951.1 - 1.1e-25 90.4 2.8 1.3e-25 90.2 1.9 1.0 1 0 0 1 1 1 1 Eukaryotic porin ParA PF10609.4 EGC36952.1 - 1.3e-36 124.3 0.2 2.4e-36 123.4 0.1 1.4 1 0 0 1 1 1 1 ParA/MinD ATPase like CbiA PF01656.18 EGC36952.1 - 3.1e-19 69.1 0.0 4.5e-19 68.6 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain ArsA_ATPase PF02374.10 EGC36952.1 - 5.5e-09 35.4 1.4 9.3e-08 31.4 0.1 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase AAA_31 PF13614.1 EGC36952.1 - 1e-08 35.2 0.0 1.2e-06 28.6 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGC36952.1 - 8.8e-08 31.5 0.0 1.8e-07 30.4 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ AAA_26 PF13500.1 EGC36952.1 - 0.00017 21.2 0.5 0.4 10.2 0.2 2.2 2 0 0 2 2 2 2 AAA domain ArgK PF03308.11 EGC36952.1 - 0.00033 19.5 0.1 0.0005 18.9 0.1 1.2 1 0 0 1 1 1 1 ArgK protein SRP54 PF00448.17 EGC36952.1 - 0.0011 18.4 0.1 0.017 14.5 0.1 2.1 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain Fer4_NifH PF00142.13 EGC36952.1 - 0.0028 16.9 0.0 0.0089 15.2 0.1 1.7 2 0 0 2 2 2 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family APS_kinase PF01583.15 EGC36952.1 - 0.0043 16.7 0.0 0.0062 16.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase DUF258 PF03193.11 EGC36952.1 - 0.008 15.3 0.5 0.018 14.2 0.1 1.8 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC36952.1 - 0.0089 15.4 0.4 0.012 15.0 0.3 1.4 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC36952.1 - 0.012 15.3 0.9 0.11 12.2 0.1 2.4 2 1 0 2 2 2 0 Part of AAA domain AAA_18 PF13238.1 EGC36952.1 - 0.026 14.8 0.0 0.053 13.8 0.0 1.6 1 1 0 1 1 1 0 AAA domain GFO_IDH_MocA PF01408.17 EGC36952.1 - 0.029 14.8 0.0 1.3 9.6 0.0 2.2 2 0 0 2 2 2 0 Oxidoreductase family, NAD-binding Rossmann fold YhjQ PF06564.7 EGC36952.1 - 0.058 12.7 0.0 0.16 11.3 0.0 1.6 2 0 0 2 2 2 0 YhjQ protein KTI12 PF08433.5 EGC36952.1 - 0.061 12.5 0.0 0.088 12.0 0.0 1.2 1 0 0 1 1 1 0 Chromatin associated protein KTI12 AAA_17 PF13207.1 EGC36952.1 - 0.063 14.0 0.5 0.18 12.6 0.3 1.6 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGC36952.1 - 0.067 12.7 0.4 0.39 10.2 0.2 2.1 2 0 0 2 2 2 0 P-loop containing region of AAA domain MobB PF03205.9 EGC36952.1 - 0.067 12.8 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RNA_helicase PF00910.17 EGC36952.1 - 0.098 12.8 0.6 0.74 10.0 0.1 2.2 1 1 1 2 2 2 0 RNA helicase AAA_22 PF13401.1 EGC36952.1 - 0.11 12.5 0.3 0.19 11.9 0.1 1.7 2 1 0 2 2 1 0 AAA domain DUF2631 PF10939.3 EGC36952.1 - 0.12 12.2 0.0 0.31 10.9 0.0 1.6 2 0 0 2 2 1 0 Protein of unknown function (DUF2631) NB-ARC PF00931.17 EGC36952.1 - 0.15 10.9 0.1 0.22 10.3 0.1 1.2 1 0 0 1 1 1 0 NB-ARC domain Cache_3 PF14827.1 EGC36952.1 - 0.16 11.9 0.0 0.42 10.5 0.0 1.8 1 0 0 1 1 1 0 Sensory domain of two-component sensor kinase MMR_HSR1 PF01926.18 EGC36952.1 - 0.25 11.3 1.4 1.3 8.9 0.9 2.0 1 1 0 1 1 1 0 50S ribosome-binding GTPase Usp PF00582.21 EGC36953.1 - 3.1e-17 63.0 0.0 1.2e-16 61.2 0.0 1.7 1 1 0 1 1 1 1 Universal stress protein family Med18 PF09637.5 EGC36953.1 - 0.064 12.7 0.0 0.068 12.7 0.0 1.1 1 0 0 1 1 1 0 Med18 protein Metallophos PF00149.23 EGC36953.1 - 0.09 12.1 0.0 0.1 11.9 0.0 1.1 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase AAA PF00004.24 EGC36954.1 - 1.1e-54 184.2 0.0 1.6e-32 112.4 0.0 2.3 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC36954.1 - 3.9e-10 40.0 0.4 0.02 14.9 0.0 4.0 2 2 1 4 4 4 2 AAA ATPase domain AAA_5 PF07728.9 EGC36954.1 - 3.2e-08 33.4 0.0 0.0041 16.8 0.0 2.5 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC36954.1 - 4.6e-07 30.0 0.1 0.033 14.3 0.0 3.9 3 2 0 3 3 2 2 AAA domain ABC_tran PF00005.22 EGC36954.1 - 1.1e-06 28.9 0.0 0.069 13.4 0.0 2.5 2 0 0 2 2 2 2 ABC transporter AAA_14 PF13173.1 EGC36954.1 - 1.9e-06 27.7 0.1 0.098 12.5 0.1 2.8 2 1 0 2 2 2 2 AAA domain TIP49 PF06068.8 EGC36954.1 - 2.9e-06 26.2 0.0 0.024 13.3 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus DUF815 PF05673.8 EGC36954.1 - 1.1e-05 24.5 0.0 0.061 12.2 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF815) NACHT PF05729.7 EGC36954.1 - 1.2e-05 25.0 0.2 0.025 14.2 0.0 3.7 2 2 1 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EGC36954.1 - 1.4e-05 25.2 0.0 0.23 11.6 0.0 2.7 2 0 0 2 2 2 2 RNA helicase Sigma54_activat PF00158.21 EGC36954.1 - 2.8e-05 23.6 0.0 0.11 12.0 0.0 2.9 2 1 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGC36954.1 - 6.4e-05 22.2 0.0 0.0041 16.3 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EGC36954.1 - 7.7e-05 22.4 1.4 0.0075 15.9 0.0 2.9 3 0 0 3 3 3 1 Archaeal ATPase RuvB_N PF05496.7 EGC36954.1 - 9.3e-05 21.5 0.0 0.0059 15.6 0.0 3.0 2 1 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_33 PF13671.1 EGC36954.1 - 0.00013 21.8 0.0 0.32 10.8 0.0 2.4 2 0 0 2 2 2 2 AAA domain Parvo_NS1 PF01057.12 EGC36954.1 - 0.00024 20.0 0.1 0.017 14.0 0.0 2.5 2 1 0 2 2 2 1 Parvovirus non-structural protein NS1 AAA_17 PF13207.1 EGC36954.1 - 0.00046 20.9 0.0 0.036 14.8 0.0 2.8 2 0 0 2 2 2 1 AAA domain Bac_DnaA PF00308.13 EGC36954.1 - 0.00079 19.1 0.0 0.16 11.5 0.0 2.7 2 1 0 2 2 2 1 Bacterial dnaA protein IstB_IS21 PF01695.12 EGC36954.1 - 0.0011 18.4 0.0 0.065 12.6 0.0 2.6 2 0 0 2 2 2 1 IstB-like ATP binding protein NB-ARC PF00931.17 EGC36954.1 - 0.0013 17.6 0.0 0.19 10.5 0.0 2.5 2 0 0 2 2 2 1 NB-ARC domain AAA_29 PF13555.1 EGC36954.1 - 0.0031 17.0 0.0 2.3 7.8 0.0 2.4 2 0 0 2 2 2 1 P-loop containing region of AAA domain Guanylate_kin PF00625.16 EGC36954.1 - 0.0037 16.7 1.2 6.8 6.0 0.0 3.7 3 0 0 3 3 3 0 Guanylate kinase AAA_19 PF13245.1 EGC36954.1 - 0.0048 16.6 0.0 0.15 11.8 0.0 2.3 2 0 0 2 2 2 1 Part of AAA domain AAA_18 PF13238.1 EGC36954.1 - 0.0059 16.9 0.0 0.9 9.8 0.0 3.2 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC36954.1 - 0.01 14.9 0.0 0.11 11.7 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Sigma54_activ_2 PF14532.1 EGC36954.1 - 0.012 15.6 0.0 0.42 10.6 0.0 2.5 2 0 0 2 2 2 0 Sigma-54 interaction domain AAA_25 PF13481.1 EGC36954.1 - 0.014 14.8 0.1 3.6 6.9 0.0 2.9 2 2 1 3 3 3 0 AAA domain KaiC PF06745.8 EGC36954.1 - 0.018 14.1 0.6 1.1 8.3 0.0 2.9 2 1 1 3 3 3 0 KaiC Zeta_toxin PF06414.7 EGC36954.1 - 0.024 13.7 0.0 1.3 8.0 0.0 2.6 3 0 0 3 3 3 0 Zeta toxin FtsK_SpoIIIE PF01580.13 EGC36954.1 - 0.046 13.1 0.0 0.61 9.5 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family DUF2075 PF09848.4 EGC36954.1 - 0.056 12.4 0.0 2.4 7.0 0.0 2.2 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2075) NTPase_1 PF03266.10 EGC36954.1 - 0.083 12.5 0.0 1.3 8.6 0.0 2.5 2 0 0 2 2 2 0 NTPase AAA_24 PF13479.1 EGC36954.1 - 0.084 12.4 0.2 4.7 6.7 0.0 2.7 3 1 0 3 3 3 0 AAA domain 2-Hacid_dh_C PF02826.14 EGC36955.1 - 1.1e-49 168.0 0.0 1.5e-49 167.5 0.0 1.2 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC36955.1 - 1.8e-31 108.3 0.0 2.1e-31 108.1 0.0 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC36955.1 - 5.2e-06 26.3 0.0 1e-05 25.4 0.0 1.4 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase Semialdhyde_dh PF01118.19 EGC36955.1 - 0.001 19.3 0.0 1.5 9.1 0.0 2.6 2 0 0 2 2 2 2 Semialdehyde dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGC36955.1 - 0.005 17.3 0.0 3.4 8.2 0.0 2.5 2 0 0 2 2 2 2 Oxidoreductase family, NAD-binding Rossmann fold DUF3965 PF13112.1 EGC36955.1 - 0.027 13.6 0.1 0.045 12.9 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3965) BBS2_N PF14781.1 EGC36955.1 - 0.054 13.1 0.3 0.94 9.1 0.0 2.7 3 0 0 3 3 3 0 Ciliary BBSome complex subunit 2, N-terminal AlaDh_PNT_N PF05222.10 EGC36955.1 - 0.13 12.2 0.0 2.7 8.0 0.0 2.2 2 0 0 2 2 2 0 Alanine dehydrogenase/PNT, N-terminal domain CPSase_L_D2 PF02786.12 EGC36956.1 - 2.8e-113 376.3 0.2 2.1e-84 282.0 0.0 2.3 2 0 0 2 2 2 2 Carbamoyl-phosphate synthase L chain, ATP binding domain CPSase_sm_chain PF00988.17 EGC36956.1 - 5.9e-51 171.3 0.0 3.2e-50 168.9 0.0 2.3 2 0 0 2 2 2 1 Carbamoyl-phosphate synthase small chain, CPSase domain OTCace_N PF02729.16 EGC36956.1 - 1.5e-43 147.8 0.0 3.2e-43 146.7 0.0 1.6 1 0 0 1 1 1 1 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain CPSase_L_D3 PF02787.14 EGC36956.1 - 1.7e-41 140.8 0.1 4e-41 139.6 0.1 1.7 1 0 0 1 1 1 1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain GATase PF00117.23 EGC36956.1 - 7.2e-40 136.4 0.0 1.9e-39 135.1 0.0 1.8 2 0 0 2 2 1 1 Glutamine amidotransferase class-I OTCace PF00185.19 EGC36956.1 - 9.1e-39 132.8 0.1 3.8e-38 130.8 0.0 2.1 2 0 0 2 2 2 1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain CPSase_L_chain PF00289.17 EGC36956.1 - 6.7e-37 125.9 0.0 4.3e-19 68.6 0.0 3.3 3 0 0 3 3 3 2 Carbamoyl-phosphate synthase L chain, N-terminal domain ATP-grasp_4 PF13535.1 EGC36956.1 - 8.3e-36 123.4 0.2 5.3e-23 81.7 0.0 2.4 2 0 0 2 2 2 2 ATP-grasp domain Dala_Dala_lig_C PF07478.8 EGC36956.1 - 4.2e-20 72.0 1.5 3.6e-10 39.5 0.1 2.6 2 0 0 2 2 2 2 D-ala D-ala ligase C-terminus MGS PF02142.17 EGC36956.1 - 1.8e-19 69.4 0.0 3.6e-18 65.2 0.0 3.1 3 0 0 3 3 3 1 MGS-like domain ATP-grasp PF02222.17 EGC36956.1 - 1.3e-17 63.6 0.1 6.9e-10 38.5 0.0 2.5 2 0 0 2 2 2 2 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGC36956.1 - 2.6e-17 62.5 0.1 9.3e-11 41.0 0.0 3.8 4 0 0 4 4 4 2 ATP-grasp in the biosynthetic pathway with Ter operon Amidohydro_4 PF13147.1 EGC36956.1 - 7e-10 39.3 0.0 0.00093 19.3 0.0 2.4 2 0 0 2 2 2 2 Amidohydrolase Amidohydro_1 PF01979.15 EGC36956.1 - 1.5e-08 34.7 0.1 3.8e-08 33.3 0.1 1.7 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGC36956.1 - 2.5e-05 23.9 0.1 7.8e-05 22.4 0.0 1.8 1 0 0 1 1 1 1 Amidohydrolase Amidohydro_3 PF07969.6 EGC36956.1 - 0.023 13.9 0.1 0.051 12.7 0.0 1.5 1 0 0 1 1 1 0 Amidohydrolase family Peptidase_C26 PF07722.8 EGC36956.1 - 0.076 12.4 0.4 1.3 8.3 0.1 2.4 1 1 1 2 2 2 0 Peptidase C26 HTH_23 PF13384.1 EGC36956.1 - 0.34 10.6 0.1 15 5.3 0.0 3.0 3 0 0 3 3 3 0 Homeodomain-like domain EF-hand_7 PF13499.1 EGC36957.1 - 2.4e-18 66.0 3.8 1.2e-08 34.9 0.7 2.3 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC36957.1 - 2.7e-15 54.8 7.0 0.00013 21.5 0.0 4.1 4 0 0 4 4 4 3 EF-hand domain EF-hand_1 PF00036.27 EGC36957.1 - 2e-13 48.5 9.4 0.00016 20.7 0.0 3.7 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC36957.1 - 8.3e-12 44.5 4.8 9.9e-05 21.8 0.1 3.6 2 2 1 3 3 3 3 EF-hand domain pair EF-hand_5 PF13202.1 EGC36957.1 - 8.7e-11 40.6 5.1 6.1e-05 22.1 0.0 3.0 3 0 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EGC36957.1 - 4.2e-06 26.7 2.9 0.00093 19.2 0.7 2.2 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1098 PF06497.6 EGC36957.1 - 0.0014 18.6 0.6 0.0044 17.0 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function (DUF1098) PqqD PF05402.7 EGC36957.1 - 0.0041 17.1 0.1 0.038 13.9 0.0 2.3 2 0 0 2 2 2 1 Coenzyme PQQ synthesis protein D (PqqD) EF-hand_10 PF14788.1 EGC36957.1 - 0.0057 16.2 1.6 0.99 9.1 0.1 3.3 3 1 1 4 4 4 1 EF hand DUF4030 PF13222.1 EGC36957.1 - 0.015 14.9 2.4 0.06 13.0 0.0 2.3 2 1 1 3 3 3 0 Protein of unknown function (DUF4030) EF-hand_4 PF12763.2 EGC36957.1 - 0.03 14.0 0.7 0.11 12.1 0.0 2.0 1 1 0 2 2 2 0 Cytoskeletal-regulatory complex EF hand DUF1024 PF06260.7 EGC36957.1 - 0.48 10.5 3.4 1.6 8.8 0.2 2.7 1 1 2 3 3 3 0 Protein of unknown function (DUF1024) DUF605 PF04652.11 EGC36960.1 - 8.7 5.6 10.5 9 5.5 7.3 1.1 1 0 0 1 1 1 0 Vta1 like Tmemb_9 PF05434.6 EGC36961.1 - 0.021 14.5 4.6 0.054 13.2 3.2 1.7 1 0 0 1 1 1 0 TMEM9 SID-1_RNA_chan PF13965.1 EGC36961.1 - 0.027 12.6 4.2 0.044 11.9 2.9 1.3 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 OATP PF03137.15 EGC36961.1 - 0.027 12.5 1.3 0.053 11.5 0.9 1.5 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Zip PF02535.17 EGC36961.1 - 0.068 12.1 0.2 0.068 12.1 0.1 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter GRP PF07172.6 EGC36961.1 - 0.21 12.0 0.1 0.21 12.0 0.1 2.2 3 0 0 3 3 3 0 Glycine rich protein family Folate_carrier PF01770.13 EGC36961.1 - 0.31 9.5 2.6 0.73 8.2 1.8 1.7 1 0 0 1 1 1 0 Reduced folate carrier OSTbeta PF15048.1 EGC36961.1 - 1.1 9.3 12.2 0.098 12.7 4.7 2.2 2 1 0 2 2 2 0 Organic solute transporter subunit beta protein Serinc PF03348.10 EGC36961.1 - 3.8 6.1 11.8 0.13 10.9 3.7 1.7 1 1 1 2 2 2 0 Serine incorporator (Serinc) DUF4484 PF14831.1 EGC36961.1 - 6.4 6.8 9.3 0.83 9.7 1.0 2.5 1 1 2 3 3 3 0 Domain of unknown function (DUF4484) HCO3_cotransp PF00955.16 EGC36961.1 - 8.3 4.9 5.5 13 4.3 3.8 1.2 1 0 0 1 1 1 0 HCO3- transporter family DUF4634 PF15465.1 EGC36962.1 - 1.1 9.4 5.7 1.9 8.6 3.0 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4634) Ras PF00071.17 EGC36963.1 - 1.1e-50 171.2 0.1 1.9e-36 124.9 0.0 2.7 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGC36963.1 - 4.1e-18 65.9 0.6 1e-10 42.1 0.0 3.0 2 0 0 2 2 2 2 Miro-like protein VWA_2 PF13519.1 EGC36963.1 - 1.9e-10 41.0 0.0 3.8e-10 40.1 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain Arf PF00025.16 EGC36963.1 - 2.2e-07 30.2 0.4 0.0002 20.6 0.0 3.2 3 1 1 4 4 4 2 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC36963.1 - 4.4e-06 26.2 0.0 1.2e-05 24.8 0.0 1.8 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain Sec23_trunk PF04811.10 EGC36963.1 - 8.3e-06 25.3 0.2 0.00033 20.1 0.1 2.3 1 1 0 1 1 1 1 Sec23/Sec24 trunk domain FeoB_N PF02421.13 EGC36963.1 - 0.0008 18.7 0.1 0.015 14.6 0.0 2.9 3 0 0 3 3 3 1 Ferrous iron transport protein B zf-Sec23_Sec24 PF04810.10 EGC36963.1 - 0.0027 17.2 4.4 0.0054 16.2 3.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EGC36963.1 - 0.0056 17.1 1.4 0.021 15.3 0.1 2.4 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain Gtr1_RagA PF04670.7 EGC36963.1 - 0.016 14.3 0.1 11 5.0 0.0 3.2 3 0 0 3 3 3 0 Gtr1/RagA G protein conserved region VWA PF00092.23 EGC36963.1 - 0.027 14.2 0.0 0.082 12.6 0.0 1.9 1 0 0 1 1 1 0 von Willebrand factor type A domain MMR_HSR1 PF01926.18 EGC36963.1 - 0.034 14.1 0.1 1.9 8.4 0.1 3.0 2 0 0 2 2 2 0 50S ribosome-binding GTPase DUF258 PF03193.11 EGC36963.1 - 0.046 12.9 0.6 0.13 11.4 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Dus PF01207.12 EGC36964.1 - 2.2e-44 151.5 0.0 3.5e-44 150.8 0.0 1.3 1 1 0 1 1 1 1 Dihydrouridine synthase (Dus) Ank_2 PF12796.2 EGC36965.1 - 1.4e-10 41.3 0.0 4.1e-10 39.8 0.0 1.8 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC36965.1 - 8.8e-07 28.4 0.4 0.0004 20.0 0.1 2.9 2 0 0 2 2 2 2 Ankyrin repeat Ank_3 PF13606.1 EGC36965.1 - 1e-06 28.3 0.2 7.5e-05 22.6 0.1 2.9 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGC36965.1 - 1e-06 29.0 0.1 1.9e-05 25.0 0.0 2.6 2 1 0 2 2 2 1 Ankyrin repeats (many copies) Ank_5 PF13857.1 EGC36965.1 - 2.7e-06 27.4 0.0 2.5e-05 24.3 0.0 2.4 2 0 0 2 2 2 1 Ankyrin repeats (many copies) Mgm101p PF06420.7 EGC36966.1 - 1.3e-72 242.6 0.0 1.9e-72 242.1 0.0 1.2 1 0 0 1 1 1 1 Mitochondrial genome maintenance MGM101 DUF2217 PF10265.4 EGC36967.1 - 2.8 6.6 10.1 3.7 6.2 7.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) LSM PF01423.17 EGC36968.1 - 7.5e-19 67.0 1.0 1.1e-18 66.5 0.7 1.2 1 0 0 1 1 1 1 LSM domain EIF_2_alpha PF07541.7 EGC36968.1 - 0.045 13.4 0.1 0.053 13.2 0.1 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 2 alpha subunit Syntaxin-6_N PF09177.6 EGC36968.1 - 0.068 13.5 0.2 0.083 13.2 0.2 1.2 1 0 0 1 1 1 0 Syntaxin 6, N-terminal DUF2208 PF09973.4 EGC36968.1 - 0.11 11.7 0.2 0.13 11.5 0.2 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2208) Pex16 PF08610.5 EGC36969.1 - 5.1e-44 150.6 0.6 6.3e-44 150.3 0.4 1.1 1 0 0 1 1 1 1 Peroxisomal membrane protein (Pex16) DUF2246 PF10229.4 EGC36969.1 - 0.33 10.2 2.8 0.49 9.6 2.0 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2246) Mucin PF01456.12 EGC36970.1 - 0.58 9.9 13.2 1.1 9.0 9.2 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF3439 PF11921.3 EGC36970.1 - 1.6 8.5 9.5 4.3 7.0 5.1 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DDE_Tnp_1_7 PF13843.1 EGC36971.1 - 2.3e-14 53.2 0.0 3.2e-14 52.7 0.0 1.1 1 0 0 1 1 1 1 Transposase IS4 Pox_C4_C10 PF03336.8 EGC36971.1 - 0.021 13.6 0.5 0.048 12.4 0.1 1.8 2 1 0 2 2 2 0 Poxvirus C4/C10 protein DDE_Tnp_4 PF13359.1 EGC36972.1 - 3.3e-09 36.5 0.0 5.1e-09 35.9 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF4451 PF14616.1 EGC36973.1 - 0.029 14.1 0.6 0.029 14.1 0.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4451) DUF190 PF02641.10 EGC36974.1 - 0.078 12.8 0.0 0.1 12.4 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized ACR, COG1993 FNIP PF05725.7 EGC36976.1 - 8.6e-61 201.6 75.4 2.2e-10 40.3 1.4 7.0 1 1 10 11 11 11 11 FNIP Repeat LRR_5 PF13306.1 EGC36976.1 - 1.7e-06 27.7 3.2 0.00036 20.2 1.2 3.2 2 1 1 3 3 3 2 Leucine rich repeats (6 copies) Lipoprotein_17 PF04200.7 EGC36976.1 - 0.39 10.8 9.8 3 8.0 0.1 3.5 2 1 2 4 4 4 0 Lipoprotein associated domain ACDC PF14733.1 EGC36976.1 - 0.65 10.1 4.6 15 5.7 0.1 3.3 1 1 2 3 3 3 0 AP2-coincident C-terminal DUF1020 PF06255.8 EGC36977.1 - 0.35 10.0 7.3 2.7 7.0 1.8 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF1020) GATA PF00320.22 EGC36978.1 - 9.7e-10 37.6 1.3 2.3e-09 36.4 0.9 1.7 1 1 0 1 1 1 1 GATA zinc finger CAV_VP3 PF04771.7 EGC36978.1 - 0.021 14.7 0.2 0.04 13.8 0.1 1.5 1 1 0 1 1 1 0 Chicken anaemia virus VP-3 protein Feld-I_B PF09252.5 EGC36979.1 - 0.032 14.1 1.6 0.097 12.5 0.3 2.3 2 0 0 2 2 2 0 Allergen Fel d I-B chain UPF0242 PF06785.6 EGC36979.1 - 0.14 10.8 11.4 0.22 10.1 7.9 1.3 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0242) GATA PF00320.22 EGC36980.1 - 1.7e-05 24.0 8.3 3e-05 23.2 5.8 1.4 1 0 0 1 1 1 1 GATA zinc finger Homeobox PF00046.24 EGC36981.1 - 2.1e-13 49.6 2.7 3.7e-07 29.6 0.0 3.0 3 0 0 3 3 3 2 Homeobox domain Homeobox_KN PF05920.6 EGC36981.1 - 5.1e-06 26.0 0.2 0.012 15.2 0.0 2.8 2 0 0 2 2 2 2 Homeobox KN domain GATA PF00320.22 EGC36982.1 - 2.5e-07 29.9 6.5 4.1e-07 29.2 4.5 1.3 1 0 0 1 1 1 1 GATA zinc finger Macoilin PF09726.4 EGC36985.1 - 0.0016 16.8 26.3 0.0023 16.3 18.2 1.2 1 0 0 1 1 1 1 Transmembrane protein CDC45 PF02724.9 EGC36985.1 - 0.015 13.3 23.8 0.025 12.6 16.5 1.3 1 0 0 1 1 1 0 CDC45-like protein Ndc1_Nup PF09531.5 EGC36985.1 - 1.9 6.7 16.9 4.5 5.5 11.7 1.7 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MIP-T3 PF10243.4 EGC36985.1 - 2.3 6.5 33.6 3.2 6.1 23.3 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF605 PF04652.11 EGC36985.1 - 2.5 7.3 35.3 3.6 6.8 24.5 1.1 1 0 0 1 1 1 0 Vta1 like DUF966 PF06136.8 EGC36985.1 - 3.5 6.9 32.8 5.1 6.4 22.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF966) BUD22 PF09073.5 EGC36985.1 - 6.3 5.7 37.9 9.5 5.1 26.3 1.1 1 0 0 1 1 1 0 BUD22 DDE_Tnp_4 PF13359.1 EGC36988.1 - 2.5e-08 33.6 0.1 3.1e-08 33.3 0.1 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3490 PF11995.3 EGC36988.1 - 0.071 12.6 0.1 0.079 12.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3490) Apc15p PF05841.6 EGC36990.1 - 7.3 7.3 14.5 8.2 7.1 10.1 1.2 1 0 0 1 1 1 0 Apc15p protein FNIP PF05725.7 EGC36991.1 - 2e-37 126.8 49.0 6.4e-12 45.2 1.7 9.2 6 2 5 11 11 11 10 FNIP Repeat Conotoxin PF02950.12 EGC36992.1 - 0.058 14.1 0.4 0.11 13.2 0.3 1.5 1 0 0 1 1 1 0 Conotoxin AIF_C PF14721.1 EGC36992.1 - 0.27 11.4 6.2 0.32 11.2 4.3 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF3086 PF11285.3 EGC36992.1 - 0.39 9.4 2.8 0.62 8.8 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3086) Gti1_Pac2 PF09729.4 EGC36992.1 - 1.1 9.1 5.7 1.3 8.8 3.9 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family POX PF07526.6 EGC36992.1 - 1.3 9.2 3.7 1.7 8.8 2.6 1.2 1 0 0 1 1 1 0 Associated with HOX DUF506 PF04720.7 EGC36992.1 - 2.7 7.5 6.3 3.1 7.3 4.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF506) Apc15p PF05841.6 EGC36992.1 - 3.1 8.5 19.2 4 8.1 13.3 1.2 1 0 0 1 1 1 0 Apc15p protein GCD14 PF08704.5 EGC36992.1 - 3.5 7.0 5.1 4 6.8 3.6 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit FlaG PF03646.10 EGC36992.1 - 4.8 7.3 13.7 6.7 6.9 9.5 1.1 1 0 0 1 1 1 0 FlaG protein Daxx PF03344.10 EGC36993.1 - 0.57 8.6 32.7 0.84 8.0 22.7 1.4 1 0 0 1 1 1 0 Daxx Family CDC45 PF02724.9 EGC36993.1 - 3.3 5.6 23.6 4.4 5.2 16.4 1.4 1 0 0 1 1 1 0 CDC45-like protein SDA1 PF05285.7 EGC36993.1 - 4.3 6.5 35.2 5.4 6.2 24.4 1.2 1 0 0 1 1 1 0 SDA1 Hid1 PF12722.2 EGC36993.1 - 5.7 4.4 21.3 6.6 4.2 14.7 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein MIP-T3 PF10243.4 EGC36993.1 - 6.6 5.0 34.8 6.9 5.0 24.1 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 TIG PF01833.19 EGC36996.1 - 7.5e-12 45.0 39.0 2.8e-05 24.0 3.1 5.5 3 2 1 5 5 5 4 IPT/TIG domain CARDB PF07705.6 EGC36996.1 - 0.014 15.4 1.4 0.014 15.4 0.9 3.5 2 1 0 2 2 2 0 CARDB TBP-binding PF09247.6 EGC36996.1 - 0.091 12.9 1.6 0.14 12.3 0.3 1.9 2 0 0 2 2 2 0 TATA box-binding protein binding TIG PF01833.19 EGC36997.1 - 5.9e-14 51.8 37.6 1.9e-06 27.7 2.2 5.7 4 2 2 6 6 6 4 IPT/TIG domain CARDB PF07705.6 EGC36997.1 - 0.015 15.2 1.7 0.015 15.2 1.2 3.1 3 0 0 3 3 3 0 CARDB TBP-binding PF09247.6 EGC36997.1 - 0.035 14.3 0.5 0.12 12.5 0.3 1.9 1 0 0 1 1 1 0 TATA box-binding protein binding TIG PF01833.19 EGC36998.1 - 2.3e-11 43.5 52.5 2.4e-06 27.4 2.4 7.3 6 2 2 8 8 8 4 IPT/TIG domain TBP-binding PF09247.6 EGC36998.1 - 0.1 12.8 2.2 0.19 11.9 0.3 2.2 2 0 0 2 2 2 0 TATA box-binding protein binding TIG PF01833.19 EGC36999.1 - 3.4e-08 33.3 46.2 2.4e-06 27.4 2.4 7.9 6 2 3 9 9 9 5 IPT/TIG domain TIG PF01833.19 EGC37000.1 - 9.2e-11 41.5 31.4 2.7e-06 27.2 1.1 5.1 3 2 0 5 5 5 4 IPT/TIG domain CARDB PF07705.6 EGC37000.1 - 0.015 15.3 1.3 0.099 12.7 0.9 2.5 1 0 0 1 1 1 0 CARDB TBP-binding PF09247.6 EGC37000.1 - 1.5 9.0 3.7 0.94 9.7 0.3 2.3 3 0 0 3 3 3 0 TATA box-binding protein binding DUF2039 PF10217.4 EGC37005.1 - 0.14 12.1 3.7 0.076 13.0 0.6 2.0 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2039) GATA PF00320.22 EGC37005.1 - 0.75 9.1 5.7 6.2 6.2 3.9 2.3 1 1 1 2 2 2 0 GATA zinc finger Maf1 PF09174.5 EGC37006.1 - 0.02 14.7 0.6 0.02 14.7 0.4 1.0 1 0 0 1 1 1 0 Maf1 regulator bZIP_1 PF00170.16 EGC37008.1 - 9.8e-08 31.8 12.3 9.8e-08 31.8 8.5 2.6 3 0 0 3 3 3 1 bZIP transcription factor bZIP_2 PF07716.10 EGC37008.1 - 7.3e-05 22.5 14.4 7.3e-05 22.5 10.0 2.7 2 0 0 2 2 2 1 Basic region leucine zipper CRM1_C PF08767.6 EGC37009.1 - 5.7e-113 377.0 11.0 5.7e-113 377.0 7.7 3.2 3 1 1 4 4 4 1 CRM1 C terminal Xpo1 PF08389.7 EGC37009.1 - 2.1e-34 118.5 5.7 2.1e-34 118.5 4.0 5.0 4 1 1 6 6 6 1 Exportin 1-like protein IBN_N PF03810.14 EGC37009.1 - 1.3e-13 50.6 0.0 7.9e-13 48.1 0.0 2.6 1 0 0 1 1 1 1 Importin-beta N-terminal domain Vac14_Fab1_bd PF12755.2 EGC37009.1 - 0.12 12.7 3.3 3.9 7.9 0.0 4.2 4 0 0 4 4 4 0 Vacuolar 14 Fab1-binding region MIP-T3 PF10243.4 EGC37010.1 - 0.00018 20.1 39.6 0.0003 19.4 27.5 1.3 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 DUF1510 PF07423.6 EGC37010.1 - 9.6 5.5 46.0 28 4.0 31.9 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Alpha_kinase PF02816.13 EGC37011.1 - 2.5e-64 216.4 0.1 2.5e-64 216.4 0.0 2.9 4 0 0 4 4 4 1 Alpha-kinase family WD40 PF00400.27 EGC37011.1 - 2.4e-45 150.8 24.6 1.5e-08 34.2 0.0 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat PID_2 PF14719.1 EGC37011.1 - 0.012 15.3 0.5 0.012 15.3 0.3 2.4 2 0 0 2 2 2 0 Phosphotyrosine interaction domain (PTB/PID) BING4CT PF08149.6 EGC37011.1 - 0.013 14.9 0.7 0.066 12.7 0.1 2.6 2 0 0 2 2 2 0 BING4CT (NUC141) domain Copper-fist PF00649.13 EGC37011.1 - 0.029 13.5 0.3 2.6 7.3 0.0 2.5 2 0 0 2 2 2 0 Copper fist DNA binding domain PQQ_3 PF13570.1 EGC37011.1 - 0.069 13.4 0.1 22 5.4 0.0 3.3 3 0 0 3 3 3 0 PQQ-like domain DUF3584 PF12128.3 EGC37011.1 - 6.1 4.0 51.4 1.2 6.3 14.4 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) NAGidase PF07555.8 EGC37012.1 - 1.8e-13 50.1 2.0 5.5e-13 48.5 1.4 1.7 1 1 0 1 1 1 1 beta-N-acetylglucosaminidase Myb_DNA-bind_6 PF13921.1 EGC37013.1 - 5.6e-17 61.5 3.6 3.4e-11 43.0 0.1 2.5 1 1 1 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-binding PF00249.26 EGC37013.1 - 5.2e-12 45.6 1.0 9.8e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Myb-like DNA-binding domain Mei4 PF13971.1 EGC37013.1 - 0.047 12.6 0.2 0.057 12.3 0.1 1.0 1 0 0 1 1 1 0 Meiosis-specific protein Mei4 PP-binding PF00550.20 EGC37014.1 - 4.7e-13 49.1 0.1 6e-13 48.8 0.1 1.2 1 0 0 1 1 1 1 Phosphopantetheine attachment site PP-binding_2 PF14573.1 EGC37014.1 - 0.00033 20.6 0.6 0.00059 19.8 0.4 1.5 1 1 0 1 1 1 1 Acyl-carrier DUF1493 PF07377.7 EGC37014.1 - 0.053 13.6 0.1 0.071 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1493) zf-PARP PF00645.13 EGC37015.1 - 1.8e-23 82.5 0.7 4.8e-23 81.1 0.5 1.8 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region zf-CCHH PF10283.4 EGC37015.1 - 7.2e-09 35.3 5.7 7.2e-09 35.3 3.9 1.9 2 0 0 2 2 2 1 Zinc-finger (CX5CX6HX5H) motif Ubie_methyltran PF01209.13 EGC37016.1 - 1.6e-91 305.5 0.0 1.9e-91 305.3 0.0 1.0 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGC37016.1 - 2.1e-13 50.5 0.0 6.2e-13 49.0 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37016.1 - 5.1e-11 42.8 0.0 1.3e-10 41.5 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC37016.1 - 4.4e-08 32.8 0.0 1.3e-07 31.3 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC37016.1 - 1.5e-07 31.2 0.0 2.5e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC37016.1 - 7.5e-06 26.3 0.0 2.6e-05 24.6 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC37016.1 - 0.0007 19.2 0.0 0.0046 16.6 0.0 2.1 2 0 0 2 2 2 1 Hypothetical methyltransferase Methyltransf_18 PF12847.2 EGC37016.1 - 0.0013 19.3 0.0 0.016 15.7 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC37016.1 - 0.015 15.3 0.0 0.048 13.6 0.0 1.8 1 1 0 1 1 1 0 Methyltransferase domain Terpene_synth PF01397.16 EGC37016.1 - 0.021 14.2 0.0 0.037 13.4 0.0 1.3 1 0 0 1 1 1 0 Terpene synthase, N-terminal domain Sororin PF09666.5 EGC37016.1 - 0.032 14.4 0.4 0.05 13.7 0.3 1.3 1 0 0 1 1 1 0 Sororin protein Redoxin PF08534.5 EGC37017.1 - 5e-10 39.1 0.0 6.2e-10 38.7 0.0 1.1 1 0 0 1 1 1 1 Redoxin PI3_PI4_kinase PF00454.22 EGC37018.1 - 5.8e-25 88.1 0.1 1.1e-24 87.2 0.0 1.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase DnaJ PF00226.26 EGC37019.1 - 0.0004 20.0 1.2 0.027 14.2 0.3 3.0 1 1 1 2 2 2 1 DnaJ domain Lipase_GDSL_3 PF14606.1 EGC37019.1 - 0.081 12.6 2.1 0.092 12.4 1.5 1.2 1 0 0 1 1 1 0 GDSL-like Lipase/Acylhydrolase family Imm20 PF15568.1 EGC37019.1 - 0.16 11.9 2.0 0.16 11.8 1.4 1.1 1 0 0 1 1 1 0 Immunity protein 20 R3H-assoc PF13902.1 EGC37019.1 - 0.16 11.9 1.6 0.29 11.1 1.1 1.6 1 1 0 1 1 1 0 R3H-associated N-terminal domain Occludin_ELL PF07303.8 EGC37019.1 - 1.1 9.9 10.7 0.21 12.3 4.5 1.8 1 1 1 2 2 2 0 Occludin homology domain PI3_PI4_kinase PF00454.22 EGC37020.1 - 2.8e-50 170.9 2.2 3.8e-50 170.5 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase FAT PF02259.18 EGC37020.1 - 5.8e-38 130.7 4.2 5.8e-38 130.7 2.9 3.5 3 1 0 3 3 3 1 FAT domain UME PF08064.8 EGC37020.1 - 4.4e-16 58.7 2.6 4.4e-16 58.7 1.8 4.5 5 1 1 6 6 6 1 UME (NUC010) domain FATC PF02260.15 EGC37020.1 - 2e-14 52.7 2.8 8.6e-14 50.6 0.2 2.6 2 0 0 2 2 2 1 FATC domain TPR_19 PF14559.1 EGC37020.1 - 0.0033 17.7 0.2 0.012 15.8 0.1 2.1 1 0 0 1 1 1 1 Tetratricopeptide repeat HEAT PF02985.17 EGC37020.1 - 0.082 13.0 0.3 5 7.4 0.0 3.5 3 0 0 3 3 3 0 HEAT repeat TPR_16 PF13432.1 EGC37020.1 - 0.98 10.1 0.0 6.9 7.4 0.0 2.1 2 0 0 2 2 2 0 Tetratricopeptide repeat TIG PF01833.19 EGC37021.1 - 3.4e-07 30.1 20.6 0.00039 20.3 0.2 4.3 4 1 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.8 EGC37021.1 - 0.0018 18.3 49.6 0.0034 17.4 8.2 3.9 3 0 0 3 3 3 2 EGF-like domain Laminin_EGF PF00053.19 EGC37021.1 - 2.1 8.3 33.8 0.26 11.2 7.2 3.1 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) HEAT PF02985.17 EGC37022.1 - 1e-15 56.3 1.8 0.04 13.9 0.0 9.0 9 0 0 9 9 9 4 HEAT repeat HEAT_2 PF13646.1 EGC37022.1 - 2.2e-14 53.4 0.0 0.0041 17.3 0.0 6.4 3 2 2 5 5 5 3 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC37022.1 - 5e-07 30.0 0.2 0.37 11.2 0.0 5.3 3 1 2 5 5 5 2 Vacuolar 14 Fab1-binding region HEAT_EZ PF13513.1 EGC37022.1 - 1.5e-06 28.4 0.0 27 5.4 0.0 7.8 7 2 1 8 8 8 0 HEAT-like repeat Cnd1 PF12717.2 EGC37022.1 - 7e-05 22.7 5.1 0.1 12.4 0.0 4.2 3 2 0 3 3 3 2 non-SMC mitotic condensation complex subunit 1 CLASP_N PF12348.3 EGC37022.1 - 0.00017 21.0 0.1 0.0078 15.5 0.0 3.3 2 1 1 3 3 3 1 CLASP N terminal DUF1981 PF09324.5 EGC37022.1 - 0.0086 15.5 1.1 3.6 7.1 0.0 4.6 4 0 0 4 4 4 1 Domain of unknown function (DUF1981) DUF1626 PF07788.6 EGC37022.1 - 0.042 13.6 0.0 0.63 9.8 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1626) DNA_alkylation PF08713.6 EGC37022.1 - 0.088 12.3 0.0 0.23 10.9 0.0 1.6 1 0 0 1 1 1 0 DNA alkylation repair enzyme Ras PF00071.17 EGC37023.1 - 3e-49 166.5 0.0 3.6e-49 166.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC37023.1 - 4e-18 66.0 0.0 8.3e-18 65.0 0.0 1.5 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC37023.1 - 2.8e-12 46.2 0.0 3.5e-12 45.9 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC37023.1 - 3.3e-05 23.1 0.0 4e-05 22.8 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region RNA_helicase PF00910.17 EGC37023.1 - 0.00096 19.3 0.2 0.018 15.2 0.2 2.2 1 1 0 1 1 1 1 RNA helicase G-alpha PF00503.15 EGC37023.1 - 0.0024 16.6 0.7 0.2 10.2 0.0 2.5 2 1 1 3 3 3 1 G-protein alpha subunit GTP_EFTU PF00009.22 EGC37023.1 - 0.023 14.1 0.0 0.14 11.5 0.0 2.1 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC37023.1 - 0.048 13.8 0.0 0.13 12.4 0.0 1.7 1 1 1 2 2 2 0 AAA domain MMR_HSR1 PF01926.18 EGC37023.1 - 0.066 13.1 0.0 0.14 12.1 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_24 PF13479.1 EGC37023.1 - 0.11 12.0 0.1 0.17 11.4 0.1 1.3 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGC37023.1 - 0.15 10.9 0.0 0.21 10.3 0.0 1.2 1 0 0 1 1 1 0 NB-ARC domain AAA_33 PF13671.1 EGC37023.1 - 0.16 11.8 0.0 0.29 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain Septin PF00735.13 EGC37023.1 - 0.16 10.9 0.1 0.37 9.7 0.0 1.6 2 0 0 2 2 2 0 Septin Med14 PF08638.6 EGC37024.1 - 2.6e-39 134.4 0.4 1.6e-38 131.9 0.2 2.3 1 1 0 1 1 1 1 Mediator complex subunit MED14 Copine PF07002.11 EGC37026.1 - 2e-36 124.9 0.4 3e-36 124.3 0.0 1.5 2 0 0 2 2 2 1 Copine C2 PF00168.25 EGC37026.1 - 3.7e-18 65.1 0.6 5.9e-09 35.6 0.4 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC37026.1 - 1e-08 35.2 0.0 2.8e-08 33.8 0.0 1.7 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC37026.1 - 0.003 17.3 0.0 0.0052 16.5 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain Usp PF00582.21 EGC37027.1 - 2.1e-21 76.5 0.0 2.6e-21 76.3 0.0 1.1 1 0 0 1 1 1 1 Universal stress protein family Aspzincin_M35 PF14521.1 EGC37027.1 - 0.026 15.0 0.1 0.038 14.4 0.1 1.2 1 0 0 1 1 1 0 Lysine-specific metallo-endopeptidase Glyco_hydro_65N PF03636.10 EGC37027.1 - 0.11 11.7 0.1 0.12 11.6 0.0 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 65, N-terminal domain CAP PF00188.21 EGC37028.1 - 4e-14 53.1 5.8 4e-14 53.1 4.0 2.0 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Prenyltransf PF01255.14 EGC37029.1 - 5.3e-77 257.9 1.5 5.3e-77 257.9 1.1 2.2 3 0 0 3 3 3 1 Putative undecaprenyl diphosphate synthase Pkinase PF00069.20 EGC37029.1 - 1.4e-12 47.2 19.3 7.3e-12 44.9 7.0 3.3 2 1 1 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37029.1 - 1.7e-11 43.6 2.8 4.2e-11 42.4 1.7 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC37029.1 - 0.0082 15.1 0.1 0.02 13.8 0.1 1.7 1 0 0 1 1 1 1 Kinase-like FNIP PF05725.7 EGC37030.1 - 3.2e-51 171.0 92.5 5.2e-12 45.5 0.9 7.5 1 1 8 9 9 9 8 FNIP Repeat DUF2476 PF10630.4 EGC37030.1 - 0.026 14.4 0.3 0.026 14.4 0.2 2.0 2 1 1 3 3 3 0 Protein of unknown function (DUF2476) Pkinase PF00069.20 EGC37031.1 - 0.00077 18.6 0.4 0.001 18.3 0.3 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37031.1 - 0.0023 17.0 0.1 0.0045 16.1 0.1 1.4 2 0 0 2 2 2 1 Protein tyrosine kinase Exo70 PF03081.10 EGC37031.1 - 0.016 14.0 0.3 0.02 13.6 0.2 1.2 1 0 0 1 1 1 0 Exo70 exocyst complex subunit DUF4098 PF13345.1 EGC37031.1 - 0.079 12.9 0.2 0.15 12.0 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4098) Robl_LC7 PF03259.12 EGC37032.1 - 0.0015 18.0 0.1 0.0066 15.9 0.1 1.9 1 1 0 1 1 1 1 Roadblock/LC7 domain Closter_coat PF01785.12 EGC37032.1 - 0.056 12.4 0.2 0.056 12.4 0.1 1.2 1 0 0 1 1 1 0 Closterovirus coat protein DUF2018 PF09442.5 EGC37032.1 - 0.068 13.7 0.1 0.15 12.6 0.1 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF2018) DUF4458 PF14660.1 EGC37033.1 - 0.087 12.8 1.8 0.18 11.8 1.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4458) DUF2018 PF09442.5 EGC37033.1 - 0.11 13.0 0.3 0.3 11.6 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF2018) LRR_4 PF12799.2 EGC37034.1 - 3e-05 23.5 0.7 0.0043 16.6 0.0 7.8 4 2 4 8 8 8 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC37034.1 - 0.0044 16.9 56.3 0.8 9.9 0.4 11.9 13 0 0 13 13 13 5 Leucine Rich repeat LRR_7 PF13504.1 EGC37034.1 - 1.3 9.5 18.2 1e+02 3.8 0.1 8.7 9 1 0 9 9 9 0 Leucine rich repeat LRR_1 PF00560.28 EGC37034.1 - 8.9 6.7 0.0 5.9 7.3 0.1 9.9 9 2 0 9 9 9 0 Leucine Rich Repeat Lipase_3 PF01764.20 EGC37035.1 - 4.1e-26 91.2 0.0 1.6e-25 89.3 0.0 1.9 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 EGC37035.1 - 0.0065 15.8 0.0 0.032 13.5 0.0 2.2 2 1 0 2 2 2 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EGC37035.1 - 0.023 14.5 0.0 0.033 14.0 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EGC37035.1 - 0.027 13.7 0.0 0.055 12.7 0.0 1.4 1 0 0 1 1 1 0 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EGC37035.1 - 0.051 13.1 0.0 0.098 12.1 0.0 1.5 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC37035.1 - 0.089 12.5 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Ribosomal_L13e PF01294.13 EGC37036.1 - 1.1e-64 217.2 8.7 1.7e-64 216.5 4.9 2.1 2 0 0 2 2 2 1 Ribosomal protein L13e DNA_pol3_delta2 PF13177.1 EGC37036.1 - 4e-13 49.3 0.8 1e-10 41.4 0.0 3.2 2 2 1 3 3 3 1 DNA polymerase III, delta subunit AAA PF00004.24 EGC37036.1 - 6.3e-13 49.0 0.0 1.6e-12 47.7 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) Rep_fac_C PF08542.6 EGC37036.1 - 4.3e-12 45.8 0.0 9.5e-12 44.7 0.0 1.6 1 0 0 1 1 1 1 Replication factor C C-terminal domain Rad17 PF03215.10 EGC37036.1 - 2.4e-08 33.1 0.0 8.3e-05 21.4 0.0 2.4 1 1 1 2 2 2 2 Rad17 cell cycle checkpoint protein AAA_14 PF13173.1 EGC37036.1 - 3.3e-08 33.4 0.0 8.1e-08 32.2 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC37036.1 - 2.2e-06 27.7 0.0 0.00014 21.9 0.0 2.4 1 1 1 2 2 2 1 AAA ATPase domain AAA_22 PF13401.1 EGC37036.1 - 4.4e-06 26.8 0.1 0.00087 19.4 0.1 2.6 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC37036.1 - 6.5e-06 25.8 0.0 2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 Part of AAA domain AAA_10 PF12846.2 EGC37036.1 - 6.4e-05 22.5 0.0 0.014 14.8 0.0 2.3 1 1 1 2 2 2 1 AAA-like domain AAA_5 PF07728.9 EGC37036.1 - 6.6e-05 22.6 0.0 0.00014 21.5 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) Viral_helicase1 PF01443.13 EGC37036.1 - 6.7e-05 22.5 0.0 0.00015 21.4 0.0 1.5 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase NTPase_1 PF03266.10 EGC37036.1 - 9.5e-05 22.1 0.1 0.11 12.2 0.0 2.5 2 0 0 2 2 2 2 NTPase AAA_18 PF13238.1 EGC37036.1 - 0.00025 21.3 0.0 0.00058 20.1 0.0 1.6 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGC37036.1 - 0.0012 18.0 0.0 0.012 14.8 0.0 2.2 1 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI DNA_pol3_delta PF06144.8 EGC37036.1 - 0.0018 17.7 0.1 0.0047 16.4 0.0 1.6 1 0 0 1 1 1 1 DNA polymerase III, delta subunit AAA_11 PF13086.1 EGC37036.1 - 0.0019 17.8 1.2 0.0051 16.4 0.0 2.0 1 1 0 2 2 2 1 AAA domain AAA_28 PF13521.1 EGC37036.1 - 0.002 18.0 0.1 0.015 15.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGC37036.1 - 0.005 16.9 0.0 0.059 13.5 0.0 2.6 3 0 0 3 3 2 1 RNA helicase AAA_3 PF07726.6 EGC37036.1 - 0.0053 16.3 0.0 0.022 14.3 0.0 2.0 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGC37036.1 - 0.0093 15.3 0.0 0.035 13.5 0.0 1.8 2 1 0 2 2 2 1 AAA domain DEAD PF00270.24 EGC37036.1 - 0.01 15.3 0.2 0.81 9.1 0.0 2.6 1 1 1 2 2 2 0 DEAD/DEAH box helicase CbiA PF01656.18 EGC37036.1 - 0.013 14.8 0.0 0.03 13.7 0.0 1.6 1 0 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain RuvB_N PF05496.7 EGC37036.1 - 0.016 14.2 0.0 0.04 12.9 0.0 1.8 1 1 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGC37036.1 - 0.017 15.9 1.1 0.071 13.9 0.7 2.0 2 1 0 2 2 1 0 AAA domain IstB_IS21 PF01695.12 EGC37036.1 - 0.021 14.2 0.0 0.053 12.9 0.0 1.7 1 0 0 1 1 1 0 IstB-like ATP binding protein Arch_ATPase PF01637.13 EGC37036.1 - 0.022 14.4 0.4 0.083 12.5 0.0 2.2 2 1 0 2 2 2 0 Archaeal ATPase T2SE PF00437.15 EGC37036.1 - 0.035 13.0 0.0 0.12 11.2 0.0 1.8 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EGC37036.1 - 0.061 13.6 0.1 0.25 11.6 0.0 2.0 2 0 0 2 2 2 0 ABC transporter MobB PF03205.9 EGC37036.1 - 0.062 12.9 0.0 0.99 9.1 0.0 2.5 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_29 PF13555.1 EGC37036.1 - 0.097 12.2 0.0 0.2 11.2 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain YtxH PF12732.2 EGC37036.1 - 1.2 9.5 4.8 2.6 8.4 2.5 2.2 2 0 0 2 2 2 0 YtxH-like protein Nodulin_late PF07127.6 EGC37037.1 - 0.041 14.0 2.6 0.041 14.0 1.8 4.6 3 1 1 4 4 4 0 Late nodulin protein DUF1682 PF07946.9 EGC37038.1 - 1.2e-79 267.4 7.9 1.6e-79 267.1 5.5 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1682) MIF4G_like_2 PF09090.6 EGC37038.1 - 0.9 8.7 9.9 1.4 8.0 4.3 2.2 2 0 0 2 2 2 0 MIF4G like C2 PF00168.25 EGC37039.1 - 9.7e-14 50.9 0.3 2.3e-13 49.7 0.2 1.7 1 0 0 1 1 1 1 C2 domain zf-RING_2 PF13639.1 EGC37039.1 - 1.5e-05 24.6 5.1 1.5e-05 24.6 3.5 6.7 5 2 0 5 5 5 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC37039.1 - 1.7e-05 24.7 3.3 1.7e-05 24.7 2.3 8.1 7 1 1 8 8 8 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37039.1 - 0.0032 17.1 6.3 0.0032 17.1 4.4 7.2 7 3 0 7 7 7 2 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC37039.1 - 0.0078 15.8 5.9 0.0078 15.8 4.1 8.2 6 2 1 7 7 7 2 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC37039.1 - 0.024 14.3 0.9 0.024 14.3 0.6 5.6 6 0 0 6 6 6 0 RING-type zinc-finger Cullin PF00888.17 EGC37040.1 - 6.8e-08 31.5 1.0 6.8e-08 31.5 0.7 2.5 3 0 0 3 3 3 1 Cullin family F-box-like PF12937.2 EGC37040.1 - 1.5e-07 31.0 0.2 5.9e-07 29.1 0.1 2.2 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC37040.1 - 0.0024 17.4 0.2 0.0096 15.5 0.0 2.1 2 0 0 2 2 2 1 F-box domain TctA PF01970.11 EGC37041.1 - 0.013 13.9 0.3 0.016 13.6 0.2 1.1 1 0 0 1 1 1 0 Tripartite tricarboxylate transporter TctA family gp37_C PF12604.3 EGC37041.1 - 0.036 13.8 0.0 0.037 13.7 0.0 1.1 1 0 0 1 1 1 0 Tail fiber protein gp37 C terminal DUF4083 PF13314.1 EGC37042.1 - 0.013 15.2 6.3 2.2 8.1 0.0 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF4083) RNA12 PF10443.4 EGC37043.1 - 1.3e-18 66.7 3.3 4.8e-11 41.7 3.4 2.6 2 0 0 2 2 2 2 RNA12 protein Arch_ATPase PF01637.13 EGC37043.1 - 1.5e-06 28.1 0.0 1.5e-06 28.1 0.0 3.0 3 1 2 5 5 5 1 Archaeal ATPase AAA_16 PF13191.1 EGC37043.1 - 0.00025 21.0 0.0 0.00061 19.8 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGC37043.1 - 0.00095 19.3 0.0 0.0024 18.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGC37043.1 - 0.04 13.4 0.4 0.11 11.9 0.0 2.0 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase DNA_pol3_theta PF06440.6 EGC37043.1 - 0.041 13.4 0.0 0.14 11.7 0.0 1.9 1 0 0 1 1 1 0 DNA polymerase III, theta subunit AAA_33 PF13671.1 EGC37043.1 - 0.074 12.9 0.0 0.76 9.6 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC37043.1 - 0.52 11.1 3.2 2.3 9.0 0.0 3.5 4 1 0 4 4 4 0 AAA domain Ctr PF04145.10 EGC37045.1 - 0.038 14.0 3.1 0.096 12.7 2.1 1.8 1 1 0 1 1 1 0 Ctr copper transporter family DUF501 PF04417.7 EGC37045.1 - 0.34 10.7 5.1 0.79 9.5 0.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF501) PCEMA1 PF07418.6 EGC37045.1 - 0.79 9.0 13.7 0.93 8.8 9.5 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 Glyco_hydro_63 PF03200.11 EGC37045.1 - 3.6 5.2 14.0 4.4 5.0 9.7 1.0 1 0 0 1 1 1 0 Mannosyl oligosaccharide glucosidase SNAPc_SNAP43 PF09808.4 EGC37046.1 - 8.6e-31 107.1 2.2 1.4e-30 106.4 1.5 1.4 1 0 0 1 1 1 1 Small nuclear RNA activating complex (SNAPc), subunit SNAP43 HlyIII PF03006.15 EGC37047.1 - 7.2e-38 130.2 12.5 8.7e-38 129.9 8.6 1.1 1 0 0 1 1 1 1 Haemolysin-III related DUF4131 PF13567.1 EGC37047.1 - 2.7 7.3 8.7 41 3.5 0.0 2.8 1 1 0 2 2 2 0 Domain of unknown function (DUF4131) GST_C PF00043.20 EGC37048.1 - 1.6e-08 34.3 0.0 4.4e-08 32.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC37048.1 - 1.1e-07 31.6 0.0 2.4e-07 30.6 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC37048.1 - 1.8e-07 31.2 0.0 3.8e-07 30.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC37048.1 - 2.8e-06 27.4 0.0 6.1e-06 26.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC37048.1 - 0.0003 21.2 0.0 0.00056 20.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC37048.1 - 0.00047 19.9 0.0 0.00092 19.0 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain PBD PF00786.23 EGC37049.1 - 1.3e-20 73.5 0.3 1.3e-20 73.5 0.2 1.8 2 0 0 2 2 2 1 P21-Rho-binding domain WH1 PF00568.18 EGC37049.1 - 3.2e-18 65.4 0.4 4.8e-18 64.8 0.3 1.2 1 0 0 1 1 1 1 WH1 domain WH2 PF02205.15 EGC37049.1 - 6.9e-05 22.3 0.2 0.00017 21.0 0.2 1.7 1 0 0 1 1 1 1 WH2 motif PAT1 PF09770.4 EGC37049.1 - 2.5 6.2 12.1 3.1 5.9 8.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 PCI PF01399.22 EGC37050.1 - 2.8e-16 59.7 0.4 2.8e-16 59.7 0.3 3.0 3 1 0 3 3 3 1 PCI domain TPR_11 PF13414.1 EGC37050.1 - 0.0052 16.4 0.0 0.37 10.4 0.0 2.7 2 0 0 2 2 2 1 TPR repeat TPR_12 PF13424.1 EGC37050.1 - 0.0091 15.9 0.2 0.052 13.4 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37050.1 - 0.036 14.4 1.3 0.4 11.0 0.0 2.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC37050.1 - 0.082 12.7 1.2 1.1 9.1 0.2 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat DsrD PF08679.6 EGC37050.1 - 0.63 10.0 6.3 25 4.9 0.0 4.6 4 1 1 5 5 5 0 Dissimilatory sulfite reductase D (DsrD) Dala_Dala_lig_N PF01820.16 EGC37051.1 - 0.19 12.0 5.6 0.19 12.0 1.9 2.2 2 0 0 2 2 2 0 D-ala D-ala ligase N-terminus Peroxin-13_N PF04088.8 EGC37051.1 - 4.1 7.3 7.8 0.79 9.6 1.5 2.2 2 0 0 2 2 2 0 Peroxin 13, N-terminal region DUF1810 PF08837.6 EGC37052.1 - 0.066 12.7 0.1 0.12 12.0 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1810) NAD_binding_6 PF08030.7 EGC37052.1 - 0.22 11.4 3.7 0.27 11.1 0.0 2.2 1 1 1 2 2 2 0 Ferric reductase NAD binding domain FNIP PF05725.7 EGC37053.1 - 7.3e-163 528.3 89.0 8.7e-14 51.2 0.2 16.1 13 2 0 15 15 15 15 FNIP Repeat DUF1769 PF08588.5 EGC37053.1 - 5.4e-07 29.4 39.0 3.4 7.6 0.0 16.5 9 6 11 20 20 20 3 Protein of unknown function (DUF1769) DUF1796 PF08795.5 EGC37053.1 - 0.083 12.5 0.6 0.21 11.2 0.4 1.6 1 0 0 1 1 1 0 Putative papain-like cysteine peptidase (DUF1796) hEGF PF12661.2 EGC37054.1 - 3.8e-06 26.5 37.1 0.00053 19.8 2.7 5.9 5 0 0 5 5 5 3 Human growth factor-like EGF EGF PF00008.22 EGC37054.1 - 0.049 13.6 49.2 0.17 11.8 6.6 5.0 4 0 0 4 4 4 0 EGF-like domain zf-NF-X1 PF01422.12 EGC37056.1 - 9.8e-06 25.4 55.4 5.2e-05 23.1 10.6 12.9 13 1 1 14 14 14 7 NF-X1 type zinc finger polyprenyl_synt PF00348.12 EGC37057.1 - 6.5e-49 166.1 0.0 7.4e-49 165.9 0.0 1.0 1 0 0 1 1 1 1 Polyprenyl synthetase TPR_11 PF13414.1 EGC37058.1 - 6.8e-15 54.4 5.6 1.5e-08 34.1 0.5 2.5 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC37058.1 - 3.7e-12 45.1 1.0 0.0037 17.0 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat SET PF00856.23 EGC37058.1 - 9.8e-11 42.2 0.0 2.2e-09 37.8 0.0 2.3 1 1 0 1 1 1 1 SET domain TPR_1 PF00515.23 EGC37058.1 - 1e-10 40.7 5.6 0.00021 20.7 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37058.1 - 4.6e-07 30.3 0.0 0.004 17.7 0.0 2.3 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37058.1 - 1.3e-06 28.1 1.3 8.3e-05 22.4 0.1 2.3 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37058.1 - 1.8e-05 24.1 10.1 0.0082 15.8 0.2 4.0 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37058.1 - 7.1e-05 23.0 0.3 0.05 13.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_3 PF07720.7 EGC37058.1 - 0.00048 19.8 0.4 0.0015 18.2 0.3 1.8 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC37058.1 - 0.00049 20.0 0.9 2 8.8 0.1 4.1 4 1 1 5 5 4 1 Tetratricopeptide repeat MIT PF04212.13 EGC37058.1 - 0.00072 19.3 4.2 0.0069 16.2 0.1 3.2 2 1 0 2 2 2 1 MIT (microtubule interacting and transport) domain TPR_6 PF13174.1 EGC37058.1 - 0.0015 18.8 2.8 19 5.9 0.0 4.0 4 0 0 4 4 3 0 Tetratricopeptide repeat RPN7 PF10602.4 EGC37058.1 - 0.0039 16.5 0.1 0.0081 15.5 0.1 1.5 1 0 0 1 1 1 1 26S proteasome subunit RPN7 TPR_14 PF13428.1 EGC37058.1 - 0.0053 17.2 0.0 7 7.5 0.0 2.9 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC37058.1 - 0.0058 16.3 0.1 0.029 14.1 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat zf-MYND PF01753.13 EGC37058.1 - 0.02 14.7 11.0 0.02 14.7 7.6 2.0 2 0 0 2 2 1 0 MYND finger DUF334 PF03904.8 EGC37058.1 - 1.8 7.8 7.4 2.1 7.5 0.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF334) tRNA_U5-meth_tr PF05958.6 EGC37059.1 - 3.9e-16 58.6 0.5 2.2e-15 56.2 0.0 2.2 2 1 0 2 2 2 1 tRNA (Uracil-5-)-methyltransferase Methyltransf_31 PF13847.1 EGC37059.1 - 1.1e-10 41.3 0.1 2.8e-10 40.0 0.1 1.8 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC37059.1 - 6.5e-07 28.8 1.2 1.2e-06 27.9 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC37059.1 - 0.00015 21.8 0.0 0.00033 20.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC37059.1 - 0.00028 19.9 0.0 0.0013 17.8 0.0 2.1 1 0 0 1 1 1 1 Putative methyltransferase RRM_1 PF00076.17 EGC37059.1 - 0.0065 16.0 0.8 0.029 14.0 0.3 2.5 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_18 PF12847.2 EGC37059.1 - 0.0067 17.0 0.0 0.015 15.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37059.1 - 0.02 15.2 0.1 0.12 12.7 0.0 2.3 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_15 PF09445.5 EGC37059.1 - 0.022 14.3 1.0 0.41 10.1 0.0 2.5 2 0 0 2 2 2 0 RNA cap guanine-N2 methyltransferase PCMT PF01135.14 EGC37059.1 - 0.034 13.6 0.0 0.065 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) UPF0020 PF01170.13 EGC37059.1 - 0.052 13.1 0.1 0.38 10.3 0.0 2.2 2 0 0 2 2 2 0 Putative RNA methylase family UPF0020 RRM_5 PF13893.1 EGC37059.1 - 0.071 12.9 0.4 0.2 11.5 0.0 1.9 2 0 0 2 2 2 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Methyltransf_12 PF08242.7 EGC37059.1 - 0.48 10.9 0.0 0.48 10.9 0.0 3.7 3 1 0 3 3 2 0 Methyltransferase domain FAA_hydrolase PF01557.13 EGC37060.1 - 2.8e-65 219.8 0.0 3.4e-65 219.5 0.0 1.1 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family DUF1730 PF08331.5 EGC37060.1 - 0.098 12.3 0.0 3.3 7.4 0.0 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF1730) ATP13 PF12921.2 EGC37063.1 - 0.015 14.6 0.2 0.028 13.7 0.1 1.5 1 1 0 1 1 1 0 Mitochondrial ATPase expression Ribosomal_S21 PF01165.15 EGC37063.1 - 0.073 12.5 0.5 0.17 11.3 0.1 1.8 2 0 0 2 2 2 0 Ribosomal protein S21 DUF2456 PF10445.4 EGC37064.1 - 0.18 11.7 5.6 0.17 11.7 0.3 2.7 3 0 0 3 3 3 0 Protein of unknown function (DUF2456) DUF3169 PF11368.3 EGC37065.1 - 0.056 12.6 9.1 0.45 9.6 1.7 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF3169) EB PF01683.13 EGC37066.1 - 0.0094 15.9 5.3 0.0094 15.9 3.6 7.3 2 2 4 6 6 6 3 EB module tRNA_synt_1c_R1 PF04558.10 EGC37067.1 - 6.2 6.3 9.4 3.9 6.9 1.7 2.1 2 0 0 2 2 2 0 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 IQ PF00612.22 EGC37068.1 - 3.5e-11 41.7 7.5 3.8e-05 22.9 0.2 2.4 2 0 0 2 2 2 2 IQ calmodulin-binding motif WW PF00397.21 EGC37068.1 - 2.6e-05 23.9 0.6 5.5e-05 22.9 0.4 1.6 1 0 0 1 1 1 1 WW domain RPEL PF02755.10 EGC37068.1 - 0.02 14.2 0.0 0.038 13.3 0.0 1.5 1 0 0 1 1 1 0 RPEL repeat DUF3275 PF11679.3 EGC37068.1 - 0.46 10.0 1.6 1.3 8.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) TUDOR PF00567.19 EGC37069.1 - 1.9e-09 37.3 0.1 5.4e-09 35.9 0.0 1.8 1 0 0 1 1 1 1 Tudor domain SMN PF06003.7 EGC37069.1 - 4.3e-07 29.3 5.5 4.3e-07 29.3 3.8 2.7 1 1 2 3 3 3 1 Survival motor neuron protein (SMN) Agenet PF05641.7 EGC37069.1 - 0.021 14.9 0.0 0.074 13.2 0.0 1.9 1 0 0 1 1 1 0 Agenet domain TraU PF06834.6 EGC37069.1 - 0.029 13.5 0.4 0.044 12.8 0.3 1.2 1 0 0 1 1 1 0 TraU protein Pex14_N PF04695.8 EGC37069.1 - 3.4 7.7 10.0 0.4 10.7 3.3 2.1 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Acyl_transf_1 PF00698.16 EGC37071.1 - 1.6e-22 80.2 0.0 2e-22 79.9 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain CBM49 PF09478.5 EGC37072.1 - 1.1e-08 35.0 1.5 2.2e-08 34.0 1.1 1.5 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 TIG PF01833.19 EGC37073.1 - 1.3e-06 28.2 18.5 0.00054 19.9 1.3 4.9 4 2 1 5 5 5 2 IPT/TIG domain EGF_2 PF07974.8 EGC37073.1 - 2.7e-06 27.4 41.5 0.0029 17.7 8.2 3.7 3 0 0 3 3 3 3 EGF-like domain LRR_1 PF00560.28 EGC37074.1 - 0.24 11.5 2.1 0.78 10.0 0.1 3.0 2 0 0 2 2 2 0 Leucine Rich Repeat EGF_2 PF07974.8 EGC37075.1 - 0.00089 19.3 10.0 0.00089 19.3 6.9 4.2 5 0 0 5 5 5 2 EGF-like domain hEGF PF12661.2 EGC37075.1 - 5.2 7.3 19.8 0.29 11.3 2.7 4.5 4 0 0 4 4 4 0 Human growth factor-like EGF Pkinase PF00069.20 EGC37076.1 - 1.7e-70 237.1 0.0 2.5e-70 236.5 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37076.1 - 8.8e-30 103.6 0.0 1.8e-28 99.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGC37076.1 - 7.4e-17 61.2 0.5 2.8e-16 59.3 0.3 2.1 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGC37076.1 - 2.1e-05 23.6 0.0 0.0047 15.9 0.0 2.4 1 1 1 2 2 2 2 Kinase-like Kdo PF06293.9 EGC37076.1 - 0.0028 16.7 0.0 0.005 15.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family PrmA PF06325.8 EGC37077.1 - 6.3e-06 25.5 0.0 1.3e-05 24.4 0.0 1.7 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC37077.1 - 6.9e-05 22.8 0.0 0.00011 22.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC37077.1 - 0.00011 21.6 0.0 0.0018 17.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase small domain Methyltransf_18 PF12847.2 EGC37077.1 - 0.00041 20.8 0.0 0.0015 19.0 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_10 PF05971.7 EGC37077.1 - 0.011 14.8 0.2 0.22 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF890) Methyltransf_23 PF13489.1 EGC37077.1 - 0.012 15.3 0.0 0.025 14.3 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGC37077.1 - 1.7 9.1 0.0 1.7 9.1 0.0 3.6 4 0 0 4 4 4 0 Methyltransferase domain CTP_transf_1 PF01148.15 EGC37078.1 - 1.8e-08 34.3 17.7 1.8e-07 31.1 12.2 2.0 1 1 0 1 1 1 1 Cytidylyltransferase family Imp-YgjV PF10688.4 EGC37078.1 - 0.27 10.6 6.3 0.13 11.6 2.8 1.6 2 0 0 2 2 2 0 Bacterial inner membrane protein Mis12 PF05859.7 EGC37080.1 - 0.015 15.0 0.3 0.025 14.4 0.2 1.3 1 0 0 1 1 1 0 Mis12 protein DUF1904 PF08921.6 EGC37080.1 - 4.2 7.4 6.7 0.66 10.0 0.4 2.6 3 1 0 3 3 3 0 Domain of unknown function (DUF1904) Nbl1_Borealin_N PF10444.4 EGC37081.1 - 1.3e-05 24.4 0.4 2.7e-05 23.4 0.3 1.5 1 0 0 1 1 1 1 Nbl1 / Borealin N terminal FtsX PF02687.16 EGC37082.1 - 2.4e-27 95.0 38.7 4.1e-17 62.0 11.6 4.6 4 1 1 5 5 5 2 FtsX-like permease family DUF2535 PF10751.4 EGC37082.1 - 0.0013 18.8 2.1 0.12 12.4 0.0 3.7 2 1 1 3 3 3 1 Protein of unknown function (DUF2535) ketoacyl-synt PF00109.21 EGC37083.1 - 2.8e-63 213.7 0.0 4.2e-63 213.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC37083.1 - 2.3e-38 132.3 0.0 3.8e-38 131.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC37083.1 - 3e-30 104.5 0.0 5.9e-30 103.5 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC37083.1 - 8.9e-21 74.3 0.0 1.4e-20 73.6 0.0 1.3 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC37083.1 - 2e-17 63.4 0.0 9.2e-17 61.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain adh_short PF00106.20 EGC37083.1 - 6e-15 55.5 0.0 9.7e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EGC37083.1 - 2e-10 40.3 0.0 2.9e-10 39.7 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.7 EGC37083.1 - 5.4e-10 39.0 0.0 1.1e-09 37.9 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC37083.1 - 2.5e-09 37.0 0.0 8.8e-09 35.2 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC37083.1 - 6.5e-09 36.1 0.0 2e-08 34.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC37083.1 - 1.7e-08 34.5 0.0 6.5e-08 32.7 0.0 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_31 PF13847.1 EGC37083.1 - 1.5e-06 27.8 0.6 1.4e-05 24.7 0.1 3.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC37083.1 - 3.5e-05 23.0 1.1 0.00011 21.4 0.0 2.2 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family ADH_zinc_N_2 PF13602.1 EGC37083.1 - 0.001 19.9 0.0 0.0022 18.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGC37083.1 - 0.0017 18.9 0.0 0.0061 17.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC37083.1 - 0.0054 15.7 0.1 0.011 14.7 0.0 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Mod_r PF07200.8 EGC37084.1 - 0.012 15.5 10.0 0.015 15.1 6.9 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Fez1 PF06818.10 EGC37084.1 - 0.012 15.5 6.2 0.015 15.3 4.3 1.1 1 0 0 1 1 1 0 Fez1 vATP-synt_E PF01991.13 EGC37084.1 - 0.017 14.3 10.1 0.02 14.2 7.0 1.2 1 0 0 1 1 1 0 ATP synthase (E/31 kDa) subunit CENP-F_leu_zip PF10473.4 EGC37084.1 - 0.027 14.3 15.9 0.041 13.7 10.7 1.5 1 1 0 1 1 1 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 IncA PF04156.9 EGC37084.1 - 0.072 12.6 12.8 0.089 12.3 8.9 1.2 1 0 0 1 1 1 0 IncA protein MAAL_C PF07476.6 EGC37084.1 - 0.093 11.6 4.0 0.11 11.3 0.5 1.9 1 1 0 2 2 2 0 Methylaspartate ammonia-lyase C-terminus DUF342 PF03961.8 EGC37084.1 - 0.15 10.4 12.4 0.17 10.2 8.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Phage_GP20 PF06810.6 EGC37084.1 - 0.2 11.1 21.8 0.49 9.8 8.6 2.9 1 1 2 3 3 3 0 Phage minor structural protein GP20 Med4 PF10018.4 EGC37084.1 - 0.3 10.4 11.6 0.37 10.1 8.0 1.1 1 0 0 1 1 1 0 Vitamin-D-receptor interacting Mediator subunit 4 Atg14 PF10186.4 EGC37084.1 - 0.32 9.8 11.0 0.37 9.6 7.7 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Phage_int_SAM_2 PF12834.2 EGC37084.1 - 0.33 11.3 2.5 0.51 10.7 1.4 1.6 1 1 0 1 1 1 0 Phage integrase, N-terminal V_ATPase_I PF01496.14 EGC37084.1 - 0.46 8.2 7.9 0.52 8.0 5.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family NPV_P10 PF05531.7 EGC37084.1 - 1.4 9.2 11.9 1.6 9.0 2.7 2.6 2 1 1 3 3 3 0 Nucleopolyhedrovirus P10 protein ACR_tran PF00873.14 EGC37084.1 - 1.7 5.9 4.7 1.9 5.7 3.3 1.0 1 0 0 1 1 1 0 AcrB/AcrD/AcrF family TBPIP PF07106.8 EGC37084.1 - 2.5 7.6 18.6 8.3 5.9 12.8 1.8 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) USP8_interact PF08941.5 EGC37084.1 - 2.9 7.2 6.9 4.3 6.6 4.1 1.7 1 1 1 2 2 2 0 USP8 interacting DUF3573 PF12097.3 EGC37084.1 - 4 5.9 7.9 4.9 5.6 5.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) TMPIT PF07851.8 EGC37084.1 - 6.5 5.7 9.2 7.7 5.4 6.3 1.1 1 0 0 1 1 1 0 TMPIT-like protein DUF3430 PF11912.3 EGC37086.1 - 1.8e-32 112.9 32.1 2.1e-32 112.6 22.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) GDI PF00996.13 EGC37087.1 - 1.9e-206 685.5 0.2 2.3e-206 685.3 0.2 1.0 1 0 0 1 1 1 1 GDP dissociation inhibitor Amino_oxidase PF01593.19 EGC37087.1 - 0.0021 17.2 0.0 0.0027 16.8 0.0 1.2 1 0 0 1 1 1 1 Flavin containing amine oxidoreductase HAD_2 PF13419.1 EGC37088.1 - 7.1e-19 68.6 0.0 1.4e-18 67.7 0.0 1.5 1 1 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Ank_2 PF12796.2 EGC37089.1 - 6.6e-19 68.0 0.1 9.6e-19 67.5 0.0 1.3 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC37089.1 - 1.6e-15 56.7 0.3 8.3e-08 32.2 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank PF00023.25 EGC37089.1 - 2.7e-15 55.2 0.0 5.5e-06 25.9 0.0 3.1 3 0 0 3 3 3 2 Ankyrin repeat Ank_4 PF13637.1 EGC37089.1 - 7.5e-15 54.9 0.8 1.3e-10 41.4 0.1 2.1 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC37089.1 - 4.1e-12 45.0 0.3 0.00014 21.7 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat WD40 PF00400.27 EGC37091.1 - 3.4e-34 115.4 12.6 2.4e-10 39.8 0.1 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGC37091.1 - 1.1e-20 73.2 0.0 3.2e-20 71.7 0.0 1.8 1 0 0 1 1 1 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex RXT2_N PF08595.6 EGC37091.1 - 0.019 14.7 3.0 0.019 14.7 2.1 2.6 3 0 0 3 3 3 0 RXT2-like, N-terminal RNase_T PF00929.19 EGC37092.1 - 3.5e-26 92.4 0.0 1.3e-25 90.6 0.0 2.1 1 0 0 1 1 1 1 Exonuclease DNA_pol_A_exo1 PF01612.15 EGC37092.1 - 0.0016 17.9 0.1 0.0083 15.6 0.0 2.2 1 1 0 1 1 1 1 3'-5' exonuclease WD40 PF00400.27 EGC37093.1 - 1.2e-21 75.7 8.1 1.1e-07 31.4 0.3 6.2 6 0 0 6 6 6 3 WD domain, G-beta repeat DUF3439 PF11921.3 EGC37093.1 - 0.024 14.3 3.6 0.06 13.0 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Menin PF05053.8 EGC37093.1 - 1.1 7.3 5.4 1.5 6.9 3.8 1.1 1 0 0 1 1 1 0 Menin Paramyxo_C PF01692.13 EGC37093.1 - 1.7 8.1 6.0 3.1 7.3 2.6 2.1 2 0 0 2 2 2 0 Paramyxovirus non-structural protein c Mucin PF01456.12 EGC37093.1 - 4.8 6.9 16.9 9.1 6.0 11.7 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein PB1 PF00564.19 EGC37094.1 - 3e-07 30.0 0.5 5.8e-07 29.0 0.3 1.4 1 0 0 1 1 1 1 PB1 domain Ras PF00071.17 EGC37096.1 - 1e-24 86.7 0.4 1.3e-24 86.4 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC37096.1 - 5e-10 39.9 0.0 8.7e-10 39.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Aldo_ket_red PF00248.16 EGC37097.1 - 5.4e-56 189.4 0.1 7.1e-56 189.0 0.1 1.1 1 0 0 1 1 1 1 Aldo/keto reductase family ATP-synt_F PF01990.12 EGC37097.1 - 0.042 14.2 0.0 2.3 8.6 0.0 2.4 2 0 0 2 2 2 0 ATP synthase (F/14-kDa) subunit Shikimate_DH PF01488.15 EGC37097.1 - 0.068 13.2 0.1 0.14 12.2 0.0 1.5 1 1 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase HAD_2 PF13419.1 EGC37097.1 - 0.14 12.4 0.0 0.22 11.7 0.0 1.4 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase NOB1_Zn_bind PF08772.6 EGC37098.1 - 0.023 14.5 0.0 0.023 14.5 0.0 1.1 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like IKKbetaNEMObind PF12179.3 EGC37098.1 - 0.11 12.3 2.6 0.17 11.7 1.8 1.3 1 0 0 1 1 1 0 I-kappa-kinase-beta NEMO binding domain Aldo_ket_red PF00248.16 EGC37099.1 - 6.3e-57 192.5 0.2 7.4e-57 192.3 0.1 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family HAD_2 PF13419.1 EGC37099.1 - 0.052 13.7 0.0 0.08 13.1 0.0 1.3 1 0 0 1 1 1 0 Haloacid dehalogenase-like hydrolase Ribosomal_S9 PF00380.14 EGC37099.1 - 0.09 13.0 0.0 0.42 10.8 0.0 2.0 2 0 0 2 2 2 0 Ribosomal protein S9/S16 E1-E2_ATPase PF00122.15 EGC37100.1 - 4.2e-34 117.5 0.6 1.3e-33 116.0 0.4 1.8 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGC37100.1 - 3.5e-24 86.0 0.0 9e-24 84.6 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC37100.1 - 1.2e-19 71.5 0.0 3.3e-15 57.0 0.0 2.7 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase P5-ATPase PF12409.3 EGC37100.1 - 1.9e-18 66.4 0.7 1.9e-18 66.4 0.5 2.9 3 0 0 3 3 3 1 P5-type ATPase cation transporter Cation_ATPase_N PF00690.21 EGC37100.1 - 0.001 18.4 0.1 0.0027 17.1 0.1 1.7 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_like2 PF13246.1 EGC37100.1 - 0.0011 18.9 0.0 0.0024 17.7 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit LIM PF00412.17 EGC37101.1 - 7.7e-60 198.8 55.7 4.2e-16 58.7 0.6 5.2 5 0 0 5 5 5 5 LIM domain APG6 PF04111.7 EGC37101.1 - 0.39 9.6 5.6 0.56 9.1 3.9 1.2 1 0 0 1 1 1 0 Autophagy protein Apg6 TIG PF01833.19 EGC37102.1 - 2.6e-07 30.5 1.0 2.6e-07 30.5 0.7 5.3 5 1 0 5 5 5 1 IPT/TIG domain EGF_2 PF07974.8 EGC37102.1 - 5.9e-05 23.1 25.3 0.004 17.2 4.9 2.7 2 0 0 2 2 2 2 EGF-like domain PMP1_2 PF08114.6 EGC37102.1 - 0.0079 15.6 4.2 0.019 14.4 2.9 1.5 1 0 0 1 1 1 1 ATPase proteolipid family Laminin_EGF PF00053.19 EGC37102.1 - 9.1 6.3 20.6 4.9 7.1 2.7 3.2 3 0 0 3 3 3 0 Laminin EGF-like (Domains III and V) Nop PF01798.13 EGC37103.1 - 7.6e-55 184.3 0.1 7.6e-55 184.3 0.1 2.0 2 0 0 2 2 2 1 Putative snoRNA binding domain NOSIC PF08060.8 EGC37103.1 - 1.9e-25 88.3 1.9 6e-25 86.8 0.2 2.5 2 0 0 2 2 2 1 NOSIC (NUC001) domain NOP5NT PF08156.8 EGC37103.1 - 5.4e-18 64.9 0.1 5.4e-18 64.9 0.1 3.3 2 1 0 2 2 2 1 NOP5NT (NUC127) domain SprA-related PF12118.3 EGC37103.1 - 0.012 14.9 27.2 0.017 14.4 18.8 1.3 1 0 0 1 1 1 0 SprA-related family GSAP-16 PF14959.1 EGC37104.1 - 7.8e-38 128.7 2.8 1.8e-37 127.5 1.9 1.7 1 0 0 1 1 1 1 gamma-Secretase-activating protein C-term DUF3430 PF11912.3 EGC37105.1 - 2.7e-20 73.1 30.7 3e-20 72.9 21.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) THOC7 PF05615.8 EGC37106.1 - 6.5e-22 78.3 13.1 6.5e-22 78.3 9.1 2.0 1 1 1 2 2 2 1 Tho complex subunit 7 V_ATPase_I PF01496.14 EGC37106.1 - 5.2 4.8 14.6 6.5 4.4 10.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2215 PF10225.4 EGC37106.1 - 5.8 6.2 7.6 40 3.5 5.3 2.0 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) FNIP PF05725.7 EGC37107.1 - 1.7e-93 306.3 56.9 8e-11 41.7 0.1 12.6 4 2 8 14 14 14 14 FNIP Repeat Bacteroid_pep PF14406.1 EGC37107.1 - 0.068 13.3 0.0 0.2 11.8 0.0 1.8 1 0 0 1 1 1 0 Ribosomally synthesized peptide in Bacteroidetes zf-CCHC PF00098.18 EGC37109.1 - 1.7e-05 24.4 1.9 3.8e-05 23.3 1.3 1.6 1 0 0 1 1 1 1 Zinc knuckle NB PF04159.8 EGC37109.1 - 0.01 15.5 2.0 0.019 14.6 1.4 1.5 1 0 0 1 1 1 0 NB glycoprotein OSTbeta PF15048.1 EGC37109.1 - 0.021 14.8 0.7 0.021 14.8 0.5 2.2 2 1 1 3 3 3 0 Organic solute transporter subunit beta protein OATP PF03137.15 EGC37109.1 - 0.074 11.0 2.3 0.18 9.8 1.6 1.6 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family DUF4199 PF13858.1 EGC37109.1 - 0.086 12.7 3.0 0.21 11.4 2.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) DUF2232 PF09991.4 EGC37109.1 - 0.18 10.7 2.4 0.25 10.2 1.7 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) FPN1 PF06963.7 EGC37109.1 - 0.21 9.9 2.4 0.29 9.4 1.7 1.2 1 0 0 1 1 1 0 Ferroportin1 (FPN1) PAT1 PF09770.4 EGC37109.1 - 0.25 9.5 47.7 0.3 9.2 33.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Folate_carrier PF01770.13 EGC37109.1 - 0.39 9.1 2.6 0.85 8.0 1.8 1.6 1 0 0 1 1 1 0 Reduced folate carrier Nucleoside_tran PF01733.13 EGC37109.1 - 0.44 9.6 5.3 0.075 12.1 0.9 1.6 2 0 0 2 2 2 0 Nucleoside transporter Med15 PF09606.5 EGC37109.1 - 0.45 8.6 48.1 0.5 8.5 33.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal DUF4446 PF14584.1 EGC37109.1 - 1.8 8.4 7.0 0.2 11.4 1.3 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4446) DUF106 PF01956.11 EGC37109.1 - 5.1 6.6 11.6 51 3.3 8.1 2.7 1 1 1 2 2 2 0 Integral membrane protein DUF106 XPG_N PF00752.12 EGC37111.1 - 2.8e-22 78.8 0.0 7.9e-22 77.4 0.0 1.8 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGC37111.1 - 2.1e-21 75.7 0.3 2.1e-21 75.7 0.2 2.3 2 0 0 2 2 2 1 XPG I-region 5_3_exonuc PF01367.15 EGC37111.1 - 0.01 16.0 0.0 0.053 13.7 0.0 2.2 1 0 0 1 1 1 0 5'-3' exonuclease, C-terminal SAM fold DnaJ PF00226.26 EGC37112.1 - 5.5e-29 99.6 3.2 5.5e-29 99.6 2.2 1.7 2 0 0 2 2 2 1 DnaJ domain CTDII PF01556.13 EGC37112.1 - 3.4e-22 78.1 3.5 6.9e-18 64.3 0.1 2.5 2 0 0 2 2 2 2 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGC37112.1 - 1.1e-13 51.0 17.0 2.4e-13 49.8 11.8 1.7 1 0 0 1 1 1 1 DnaJ central domain HypA PF01155.14 EGC37112.1 - 0.022 14.4 6.7 0.064 12.9 1.3 2.3 2 0 0 2 2 2 0 Hydrogenase expression/synthesis hypA family Sigma70_ner PF04546.8 EGC37112.1 - 0.24 10.9 1.4 0.39 10.3 1.0 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region Cytochrom_c3_2 PF14537.1 EGC37112.1 - 3 8.2 10.7 4.8 7.5 2.9 2.3 1 1 2 3 3 3 0 Cytochrome c3 DUF605 PF04652.11 EGC37113.1 - 0.051 12.9 19.6 0.058 12.7 13.6 1.1 1 0 0 1 1 1 0 Vta1 like CDC27 PF09507.5 EGC37113.1 - 1.1 8.3 8.3 1.4 8.0 5.8 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 Shisa PF13908.1 EGC37113.1 - 1.3 9.1 11.2 2 8.5 7.7 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator PAT1 PF09770.4 EGC37113.1 - 3.3 5.8 33.8 4.1 5.5 23.4 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Suf PF05843.9 EGC37113.1 - 3.7 7.2 6.7 5 6.7 4.7 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Herpes_DNAp_acc PF04929.7 EGC37113.1 - 4.3 6.2 6.0 5.1 5.9 4.2 1.1 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Mtc PF03820.12 EGC37114.1 - 6.1e-99 330.5 0.2 7e-99 330.3 0.2 1.0 1 0 0 1 1 1 1 Tricarboxylate carrier PX PF00787.19 EGC37116.1 - 3.9e-12 45.9 0.6 3.9e-12 45.9 0.4 3.6 2 1 1 3 3 3 1 PX domain MMR_HSR1 PF01926.18 EGC37116.1 - 2.7e-06 27.3 0.1 5.9e-05 22.9 0.1 2.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC37116.1 - 2.5e-05 24.1 1.2 2.5e-05 24.1 0.8 6.5 3 3 0 3 3 3 1 Dynamin family Miro PF08477.8 EGC37116.1 - 0.11 13.0 0.0 0.11 13.0 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein Ank PF00023.25 EGC37117.1 - 4.8e-13 48.1 0.0 1.2e-10 40.6 0.0 2.2 2 0 0 2 2 2 2 Ankyrin repeat Ank_4 PF13637.1 EGC37117.1 - 1.3e-11 44.6 0.0 3.2e-11 43.4 0.0 1.6 1 1 1 2 2 2 1 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC37117.1 - 1.6e-11 44.3 0.0 1.9e-11 44.1 0.0 1.1 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC37117.1 - 2.2e-10 40.4 0.0 3.5e-10 39.7 0.0 1.4 1 1 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC37117.1 - 2e-09 36.7 0.0 3.2e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeat EGF_2 PF07974.8 EGC37118.1 - 1.3e-11 44.4 68.0 2.2e-05 24.5 11.0 4.8 4 0 0 4 4 4 4 EGF-like domain TMEM154 PF15102.1 EGC37118.1 - 0.032 13.9 3.4 0.082 12.6 2.4 1.7 1 0 0 1 1 1 0 TMEM154 protein family LRR_1 PF00560.28 EGC37118.1 - 0.045 13.7 7.9 2.2 8.6 0.1 5.4 5 0 0 5 5 5 0 Leucine Rich Repeat JAB PF01398.16 EGC37119.1 - 3.2e-12 46.2 0.0 6e-12 45.3 0.0 1.5 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease FAM117 PF15388.1 EGC37119.1 - 0.0066 15.7 0.0 0.0098 15.1 0.0 1.2 1 0 0 1 1 1 1 Protein Family FAM117 DUF1848 PF08902.6 EGC37119.1 - 0.042 13.3 0.3 0.058 12.9 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1848) Streptin-Immun PF11083.3 EGC37119.1 - 0.25 11.3 6.1 0.065 13.2 1.2 2.2 2 0 0 2 2 2 0 Lantibiotic streptin immunity protein Kinesin PF00225.18 EGC37120.1 - 9.9e-113 376.2 2.2 9.9e-113 376.2 1.5 2.5 2 0 0 2 2 2 1 Kinesin motor domain APG6 PF04111.7 EGC37120.1 - 0.0032 16.5 15.9 0.0032 16.5 11.0 4.5 2 2 2 4 4 4 1 Autophagy protein Apg6 zf-RING_2 PF13639.1 EGC37121.1 - 7.9e-09 35.2 8.8 1.6e-08 34.2 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC37121.1 - 1.5e-07 30.9 11.4 4.3e-07 29.4 7.9 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC37121.1 - 3.1e-06 26.7 6.2 7.3e-06 25.5 4.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37121.1 - 5.1e-06 26.5 4.5 1.8e-05 24.7 3.1 2.0 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC37121.1 - 1.1e-05 25.3 10.7 2.7e-05 24.0 7.4 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC37121.1 - 0.0008 19.2 9.2 0.0031 17.3 6.4 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC37121.1 - 0.013 15.0 8.6 0.027 14.0 6.0 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_5 PF14634.1 EGC37121.1 - 0.017 14.8 9.4 0.042 13.5 6.5 1.8 1 0 0 1 1 1 0 zinc-RING finger domain zf-Apc11 PF12861.2 EGC37121.1 - 0.028 14.2 1.0 0.062 13.1 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC37121.1 - 0.031 13.9 5.8 0.12 12.0 4.0 2.1 1 0 0 1 1 1 0 RING-type zinc-finger DUF1272 PF06906.6 EGC37121.1 - 0.82 9.5 6.4 2.2 8.1 4.5 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Oxidored_q3 PF00499.15 EGC37121.1 - 8.5 6.1 9.1 20 4.9 6.3 1.6 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Sugar_tr PF00083.19 EGC37122.1 - 1.3e-91 307.4 33.0 2.1e-91 306.8 22.8 1.2 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_1 PF07690.11 EGC37122.1 - 1.9e-37 128.8 31.9 3.7e-34 118.0 18.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily TRI12 PF06609.8 EGC37122.1 - 9.1e-05 20.8 4.1 9.1e-05 20.8 2.8 2.0 2 0 0 2 2 2 1 Fungal trichothecene efflux pump (TRI12) zf-CCHC_3 PF13917.1 EGC37123.1 - 0.11 12.2 2.7 0.25 11.1 1.9 1.6 1 0 0 1 1 1 0 Zinc knuckle TBCC PF07986.7 EGC37124.1 - 9.5e-28 96.0 6.9 1.7e-27 95.1 4.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EGC37124.1 - 0.73 9.1 14.3 0.064 12.5 5.7 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGC37125.1 - 1.2e-27 95.7 6.9 2.1e-27 94.9 4.8 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C CAP_C PF08603.6 EGC37125.1 - 0.82 8.9 14.1 0.067 12.5 5.6 2.1 2 0 0 2 2 2 0 Adenylate cyclase associated (CAP) C terminal FYVE PF01363.16 EGC37126.1 - 1.6e-05 24.6 6.8 1.8e-05 24.5 2.9 2.1 2 0 0 2 2 2 1 FYVE zinc finger zf-4CXXC_R1 PF10497.4 EGC37126.1 - 0.031 14.3 5.3 0.043 13.9 2.3 2.0 2 0 0 2 2 2 0 Zinc-finger domain of monoamine-oxidase A repressor R1 IBR PF01485.16 EGC37126.1 - 0.045 13.6 13.0 3.6 7.5 4.3 3.3 2 1 1 3 3 3 0 IBR domain FYVE_2 PF02318.11 EGC37126.1 - 0.11 12.4 11.0 0.034 14.0 4.7 2.2 2 1 0 2 2 2 0 FYVE-type zinc finger zinc-ribbons_6 PF07191.7 EGC37126.1 - 1 9.2 9.8 6.1 6.7 3.7 2.7 2 1 0 2 2 2 0 zinc-ribbons Zn_Tnp_IS1595 PF12760.2 EGC37126.1 - 3.4 7.5 10.0 2.3 8.1 0.4 2.9 3 0 0 3 3 3 0 Transposase zinc-ribbon domain C1_1 PF00130.17 EGC37126.1 - 6.5 6.5 14.3 0.038 13.7 2.1 2.8 3 1 0 3 3 3 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-CCHC_3 PF13917.1 EGC37129.1 - 0.3 10.8 2.4 0.82 9.4 1.7 1.8 1 1 0 1 1 1 0 Zinc knuckle ADH_zinc_N PF00107.21 EGC37130.1 - 2.9e-17 62.4 0.0 4.5e-17 61.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC37130.1 - 2.1e-05 25.3 0.0 4.2e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase B-block_TFIIIC PF04182.7 EGC37132.1 - 5.9 6.8 13.9 9.4 6.1 0.2 4.6 4 0 0 4 4 4 0 B-block binding subunit of TFIIIC FNIP PF05725.7 EGC37133.1 - 4e-58 193.1 77.9 4.5e-10 39.3 0.4 10.6 5 3 8 13 13 13 11 FNIP Repeat DUF1769 PF08588.5 EGC37133.1 - 0.00064 19.6 4.4 13 5.8 0.0 7.5 7 2 2 9 9 9 1 Protein of unknown function (DUF1769) COPIIcoated_ERV PF07970.7 EGC37133.1 - 0.12 12.0 0.3 0.87 9.1 0.0 2.5 2 1 0 3 3 3 0 Endoplasmic reticulum vesicle transporter DDE_Tnp_4 PF13359.1 EGC37134.1 - 5.3e-11 42.3 0.0 7.7e-11 41.8 0.0 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC37134.1 - 7.2e-06 25.6 0.1 1.2e-05 25.0 0.1 1.3 1 0 0 1 1 1 1 Transposase DDE domain HTH_Tnp_4 PF13613.1 EGC37134.1 - 0.0047 16.4 0.2 0.0092 15.4 0.1 1.4 1 0 0 1 1 1 1 Helix-turn-helix of DDE superfamily endonuclease FNIP PF05725.7 EGC37136.1 - 4.9e-45 151.2 67.7 1.1e-09 38.0 2.1 7.8 1 1 10 11 11 11 11 FNIP Repeat LRR_2 PF07723.8 EGC37136.1 - 0.13 12.7 4.2 0.88 10.1 0.0 3.6 3 0 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.7 EGC37137.1 - 6.5e-75 246.8 87.9 1.7e-09 37.4 1.8 15.2 5 4 10 17 17 17 17 FNIP Repeat NPR3 PF03666.8 EGC37140.1 - 3.1e-42 144.6 17.5 4.7e-28 97.9 5.0 2.5 1 1 1 3 3 3 2 Nitrogen Permease regulator of amino acid transport activity 3 Secretin_N_2 PF07655.8 EGC37140.1 - 0.91 9.9 14.3 1.7 9.1 9.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF3816 PF12822.2 EGC37141.1 - 0.015 15.2 0.1 0.016 15.1 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3816) MKT1_C PF12246.3 EGC37142.1 - 5.8e-49 166.2 1.3 9.7e-49 165.5 0.9 1.4 1 0 0 1 1 1 1 Temperature dependent protein affecting M2 dsRNA replication MKT1_N PF12247.3 EGC37142.1 - 2.7e-23 82.1 0.7 9.7e-23 80.3 0.0 2.4 3 0 0 3 3 3 1 Temperature dependent protein affecting M2 dsRNA replication XPG_I PF00867.13 EGC37142.1 - 1.2e-09 38.1 0.0 2.8e-09 36.8 0.0 1.7 1 0 0 1 1 1 1 XPG I-region XPG_N PF00752.12 EGC37142.1 - 0.0054 16.9 0.0 0.026 14.7 0.0 2.2 2 0 0 2 2 2 1 XPG N-terminal domain DUF1673 PF07895.6 EGC37143.1 - 0.0066 15.9 3.4 0.011 15.2 2.4 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) Spore_III_AE PF09546.5 EGC37143.1 - 0.027 13.4 1.5 0.031 13.2 1.0 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) Bac_export_2 PF01312.14 EGC37143.1 - 0.054 12.3 2.2 0.083 11.7 1.5 1.3 1 0 0 1 1 1 0 FlhB HrpN YscU SpaS Family Na_Ca_ex PF01699.19 EGC37145.1 - 0.0015 18.1 0.4 0.0019 17.7 0.3 1.2 1 0 0 1 1 1 1 Sodium/calcium exchanger protein DUF4231 PF14015.1 EGC37145.1 - 0.022 14.7 0.3 0.026 14.4 0.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF4231) Sdh_cyt PF01127.17 EGC37145.1 - 0.045 13.5 2.7 0.053 13.3 1.9 1.2 1 0 0 1 1 1 0 Succinate dehydrogenase/Fumarate reductase transmembrane subunit DUF872 PF05915.7 EGC37145.1 - 0.11 12.4 1.3 0.14 12.0 0.9 1.3 1 1 0 1 1 1 0 Eukaryotic protein of unknown function (DUF872) Arif-1 PF06770.6 EGC37145.1 - 0.11 11.8 0.4 0.11 11.8 0.3 1.0 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) DUF2116 PF09889.4 EGC37145.1 - 0.25 11.1 4.9 0.88 9.4 0.2 2.1 1 1 1 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF2721 PF11026.3 EGC37145.1 - 0.28 10.7 2.8 0.43 10.2 2.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2721) DUF843 PF05814.6 EGC37145.1 - 0.37 10.6 5.6 0.38 10.5 3.0 1.7 1 1 1 2 2 2 0 Baculovirus protein of unknown function (DUF843) Sec20 PF03908.8 EGC37145.1 - 0.42 10.3 2.0 9.3 6.0 0.1 2.1 1 1 1 2 2 2 0 Sec20 DUF3357 PF11837.3 EGC37145.1 - 0.75 9.6 5.0 7.6 6.4 0.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF3357) Pox_A14 PF05767.7 EGC37145.1 - 1.6 8.7 5.3 7.9 6.5 0.3 2.0 1 1 1 2 2 2 0 Poxvirus virion envelope protein A14 DUF454 PF04304.8 EGC37145.1 - 1.9 8.6 7.2 1.9 8.5 2.2 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF454) OppC_N PF12911.2 EGC37145.1 - 6.7 6.1 10.3 13 5.2 0.0 2.4 2 1 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C SdpI PF13630.1 EGC37145.1 - 8.7 6.1 9.2 16 5.3 6.4 1.5 1 1 0 1 1 1 0 SdpI/YhfL protein family Peroxin-3 PF04882.7 EGC37146.1 - 2.2e-48 165.0 19.2 8.8e-47 159.7 9.8 2.0 1 1 1 2 2 2 2 Peroxin-3 DUF3045 PF11243.3 EGC37146.1 - 0.069 13.3 1.1 0.2 11.8 0.1 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3045) TFIIB PF00382.14 EGC37147.1 - 2.6e-33 113.6 0.3 2.1e-16 59.4 0.0 2.7 2 0 0 2 2 2 2 Transcription factor TFIIB repeat BRF1 PF07741.8 EGC37147.1 - 1.6e-06 28.2 6.1 1.6e-06 28.2 4.2 2.7 2 0 0 2 2 2 1 Brf1-like TBP-binding domain Cyclin_N PF00134.18 EGC37147.1 - 2.1e-05 24.0 0.2 0.3 10.6 0.1 2.7 2 0 0 2 2 2 2 Cyclin, N-terminal domain RRN7 PF11781.3 EGC37147.1 - 0.0023 17.3 0.9 0.0048 16.3 0.6 1.6 1 0 0 1 1 1 1 RNA polymerase I-specific transcription initiation factor Rrn7 TF_Zn_Ribbon PF08271.7 EGC37147.1 - 0.0045 16.2 2.3 0.0045 16.2 1.6 2.1 2 0 0 2 2 2 1 TFIIB zinc-binding AAA_23 PF13476.1 EGC37147.1 - 0.0079 16.5 11.2 0.0079 16.5 7.8 2.3 3 0 0 3 3 3 1 AAA domain DUF2318 PF10080.4 EGC37147.1 - 0.13 12.0 0.4 0.27 11.0 0.3 1.5 1 0 0 1 1 1 0 Predicted membrane protein (DUF2318) Prok-RING_1 PF14446.1 EGC37147.1 - 0.67 9.7 2.5 1.4 8.6 1.7 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 A2L_zn_ribbon PF08792.5 EGC37147.1 - 1.4 8.4 6.0 0.76 9.3 1.9 2.1 2 0 0 2 2 2 0 A2L zinc ribbon domain DDHD PF02862.12 EGC37147.1 - 3.1 7.5 7.6 6.4 6.5 5.2 1.5 1 0 0 1 1 1 0 DDHD domain NUDIX PF00293.23 EGC37148.1 - 6.1e-17 61.5 0.0 8.7e-17 61.0 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Chromate_transp PF02417.10 EGC37149.1 - 0.078 12.5 2.6 0.16 11.5 1.8 1.5 1 0 0 1 1 1 0 Chromate transporter zf-DHHC PF01529.15 EGC37150.1 - 5.4 6.3 11.3 37 3.6 5.8 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase EF-hand_7 PF13499.1 EGC37151.1 - 0.00015 21.7 0.1 0.00022 21.2 0.1 1.3 1 1 0 1 1 1 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC37151.1 - 0.00043 19.3 0.4 0.011 14.9 0.1 2.1 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGC37151.1 - 0.0044 16.7 0.1 0.071 13.0 0.0 2.1 2 0 0 2 2 2 1 EF-hand domain EF-hand_7 PF13499.1 EGC37152.1 - 1.3e-11 44.4 7.4 3.5e-07 30.2 2.6 3.2 2 1 1 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC37152.1 - 7.1e-10 37.4 6.0 0.0012 17.9 0.0 3.4 3 0 0 3 3 3 3 EF hand EF-hand_6 PF13405.1 EGC37152.1 - 5.9e-08 31.9 6.6 0.0009 18.9 0.0 3.7 4 0 0 4 4 4 2 EF-hand domain EF-hand_8 PF13833.1 EGC37152.1 - 6.8e-05 22.3 1.7 0.0071 15.9 0.0 2.7 2 0 0 2 2 2 1 EF-hand domain pair Pox_VLTF3 PF04947.9 EGC37152.1 - 0.0014 18.1 2.2 0.0018 17.8 1.5 1.1 1 0 0 1 1 1 1 Poxvirus Late Transcription Factor VLTF3 like EF-hand_5 PF13202.1 EGC37152.1 - 0.002 17.3 0.2 0.002 17.3 0.1 2.9 3 0 0 3 3 3 1 EF hand SPARC_Ca_bdg PF10591.4 EGC37152.1 - 0.003 17.5 0.1 0.54 10.2 0.0 2.6 1 1 1 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF3909 PF13077.1 EGC37152.1 - 0.11 12.3 1.3 0.19 11.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF3909) Glyoxalase PF00903.20 EGC37153.1 - 7.4e-16 58.2 0.7 5.5e-11 42.5 0.0 2.3 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EGC37153.1 - 9.2e-11 41.8 0.2 3e-09 36.9 0.1 2.2 2 0 0 2 2 2 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_4 PF13669.1 EGC37153.1 - 1.4e-06 28.2 0.0 0.012 15.6 0.0 2.4 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGC37153.1 - 1.6e-06 28.6 0.0 0.0063 17.1 0.0 2.6 2 0 0 2 2 2 2 Glyoxalase-like domain DUF1162 PF06650.7 EGC37154.1 - 8.3e-49 166.2 11.7 1.1e-47 162.5 0.1 4.5 4 1 0 4 4 4 2 Protein of unknown function (DUF1162) Chorein_N PF12624.2 EGC37154.1 - 1.5e-39 134.1 2.8 6.3e-39 132.1 1.9 2.2 1 0 0 1 1 1 1 N-terminal region of Chorein, a TM vesicle-mediated sorter ATG_C PF09333.6 EGC37154.1 - 5.1e-08 32.9 0.0 3.1e-06 27.2 0.1 3.0 3 0 0 3 3 3 1 ATG C terminal domain zf-C3HC4_3 PF13920.1 EGC37155.1 - 6.1e-09 35.4 8.1 1.1e-08 34.6 5.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC37155.1 - 4.5e-08 32.7 9.0 8.2e-08 31.9 6.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC37155.1 - 9.1e-08 31.6 10.4 9.1e-08 31.6 7.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37155.1 - 1.9e-06 27.7 10.3 3.6e-06 26.8 7.2 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37155.1 - 3.6e-06 26.9 6.5 9.8e-06 25.5 4.5 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC37155.1 - 0.00057 19.5 9.8 0.0011 18.6 6.8 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC37155.1 - 0.0012 18.6 8.1 0.0035 17.1 5.5 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC37155.1 - 0.086 12.4 9.0 0.35 10.4 6.3 2.0 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC37155.1 - 0.16 11.6 7.0 0.57 9.9 4.8 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC37155.1 - 0.33 10.8 5.2 1 9.2 3.6 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EGC37155.1 - 0.47 10.3 7.6 2.8 7.8 5.1 2.2 1 1 0 1 1 1 0 Double zinc ribbon SapB_2 PF03489.12 EGC37156.1 - 6.8e-07 29.1 7.2 0.00013 21.9 0.1 3.1 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC37156.1 - 1.1e-06 28.3 1.8 0.017 14.9 0.0 3.6 3 1 0 3 3 3 2 Saposin-like type B, region 1 zinc_ribbon_5 PF13719.1 EGC37156.1 - 0.00081 18.9 2.0 0.93 9.1 0.4 2.6 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_4 PF13717.1 EGC37156.1 - 0.00083 19.0 2.1 1.1 9.0 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain Copper-fist PF00649.13 EGC37156.1 - 0.027 13.6 2.2 0.64 9.2 0.3 2.6 2 0 0 2 2 2 0 Copper fist DNA binding domain p450 PF00067.17 EGC37157.1 - 2.2e-62 211.0 0.4 2.9e-62 210.7 0.3 1.1 1 0 0 1 1 1 1 Cytochrome P450 Cons_hypoth698 PF03601.9 EGC37157.1 - 0.027 13.1 4.5 0.063 11.9 3.1 1.6 1 1 0 1 1 1 0 Conserved hypothetical protein 698 GNT-I PF03071.10 EGC37158.1 - 5.4e-31 107.5 6.7 1.3e-30 106.3 4.7 1.5 1 1 0 1 1 1 1 GNT-I family Glycos_transf_2 PF00535.21 EGC37158.1 - 0.0026 17.4 5.5 0.036 13.7 0.2 2.9 3 0 0 3 3 3 2 Glycosyl transferase family 2 PglZ PF08665.7 EGC37158.1 - 0.044 13.4 0.2 0.097 12.3 0.1 1.6 1 1 0 1 1 1 0 PglZ domain C2 PF00168.25 EGC37159.1 - 9.6e-21 73.4 0.1 2.3e-20 72.2 0.0 1.7 1 0 0 1 1 1 1 C2 domain YbjQ_1 PF01906.12 EGC37159.1 - 8.3e-09 35.8 0.0 0.006 16.9 0.0 3.9 3 1 0 3 3 3 2 Putative heavy-metal-binding DUF4156 PF13698.1 EGC37159.1 - 0.00024 20.9 0.1 0.08 12.8 0.0 3.6 3 0 0 3 3 3 1 Domain of unknown function (DUF4156) Peptidase_S8 PF00082.17 EGC37160.1 - 6.1e-41 140.4 3.6 1e-40 139.6 2.5 1.4 1 0 0 1 1 1 1 Subtilase family Med15 PF09606.5 EGC37160.1 - 0.00086 17.6 9.7 0.0012 17.2 6.7 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal Whirly PF08536.6 EGC37160.1 - 0.055 12.9 0.1 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Whirly transcription factor DivIC PF04977.10 EGC37160.1 - 8.3 5.9 17.0 22 4.6 7.5 2.6 2 0 0 2 2 2 0 Septum formation initiator Erf4 PF10256.4 EGC37161.1 - 0.018 14.9 18.9 0.039 13.8 7.4 3.0 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family Oxidored_q4 PF00507.14 EGC37161.1 - 0.06 13.1 9.5 0.073 12.8 5.4 2.0 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Surf_Ag_VNR PF07244.10 EGC37161.1 - 3.6 8.0 9.3 1.6 9.1 0.2 2.9 3 0 0 3 3 3 0 Surface antigen variable number repeat Virul_fac_BrkB PF03631.10 EGC37162.1 - 2.5e-05 23.7 1.4 4.1e-05 23.0 1.0 1.3 1 0 0 1 1 1 1 Virulence factor BrkB VIT1 PF01988.14 EGC37162.1 - 8.7e-05 22.1 0.2 0.00015 21.3 0.2 1.3 1 0 0 1 1 1 1 VIT family Erf4 PF10256.4 EGC37162.1 - 0.00015 21.6 2.7 0.0083 15.9 1.9 2.4 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family DUF368 PF04018.8 EGC37162.1 - 0.00082 18.6 3.4 0.0013 17.9 2.4 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF368) MFS_1 PF07690.11 EGC37162.1 - 0.0017 17.1 0.1 0.002 16.8 0.1 1.1 1 0 0 1 1 1 1 Major Facilitator Superfamily DUF4191 PF13829.1 EGC37162.1 - 0.0031 16.6 3.0 0.0031 16.6 2.1 1.8 2 0 0 2 2 2 1 Domain of unknown function (DUF4191) Suf PF05843.9 EGC37162.1 - 0.035 13.8 10.5 0.06 13.0 7.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) RED_N PF07808.8 EGC37162.1 - 0.054 12.7 11.9 0.094 11.9 8.3 1.4 1 0 0 1 1 1 0 RED-like protein N-terminal region Band_3_cyto PF07565.8 EGC37162.1 - 0.36 10.3 5.5 0.5 9.8 3.8 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Peptidase_U57 PF05582.7 EGC37162.1 - 0.46 9.3 4.6 0.64 8.9 3.2 1.2 1 0 0 1 1 1 0 YabG peptidase U57 DUF4557 PF15101.1 EGC37162.1 - 0.91 9.3 16.2 1.6 8.5 11.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) DUF106 PF01956.11 EGC37162.1 - 1.1 8.7 11.7 2.6 7.5 7.7 1.8 1 1 1 2 2 2 0 Integral membrane protein DUF106 Peptidase_U4 PF03419.8 EGC37162.1 - 3.4 6.6 14.0 0.013 14.6 3.3 1.7 2 0 0 2 2 2 0 Sporulation factor SpoIIGA TRP PF06011.7 EGC37162.1 - 4.5 5.7 14.9 15 4.0 10.3 1.8 1 1 0 1 1 1 0 Transient receptor potential (TRP) ion channel Ctr PF04145.10 EGC37162.1 - 5.3 7.0 7.8 10 6.1 5.3 1.7 1 1 0 1 1 1 0 Ctr copper transporter family ATAD4 PF15321.1 EGC37162.1 - 9.9 7.2 8.9 23 6.0 6.2 1.6 1 0 0 1 1 1 0 ATPase family AAA domain containing 4 UCH PF00443.24 EGC37165.1 - 4.4e-55 186.6 0.9 5.4e-55 186.3 0.6 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC37165.1 - 6.3e-18 65.2 3.9 1.5e-17 63.9 2.7 1.5 1 1 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase ubiquitin PF00240.18 EGC37165.1 - 1e-09 37.6 0.0 2.1e-09 36.6 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Peptidase_C98 PF15499.1 EGC37165.1 - 0.031 13.5 2.4 0.087 12.1 0.1 2.5 3 0 0 3 3 3 0 Ubiquitin-specific peptidase-like, SUMO isopeptidase Rad60-SLD PF11976.3 EGC37165.1 - 0.036 13.7 0.1 0.1 12.2 0.1 1.8 2 0 0 2 2 2 0 Ubiquitin-2 like Rad60 SUMO-like DUF3911 PF13050.1 EGC37165.1 - 0.26 11.4 1.7 0.71 10.0 0.0 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF3911) Acetyltransf_1 PF00583.19 EGC37167.1 - 2.5e-14 53.0 0.0 3.5e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC37167.1 - 1.4e-12 47.5 0.1 2e-12 47.0 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC37167.1 - 3.3e-09 36.8 0.0 4e-09 36.6 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC37167.1 - 5.7e-07 29.6 0.1 6.7e-07 29.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC37167.1 - 5.7e-06 26.2 0.0 8.5e-06 25.7 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC37167.1 - 1.8e-05 24.5 0.0 3.4e-05 23.6 0.0 1.5 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGC37167.1 - 4.2e-05 23.2 0.0 7.7e-05 22.3 0.0 1.5 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_3 PF13302.1 EGC37167.1 - 4.6e-05 23.6 0.1 5.8e-05 23.2 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC37167.1 - 6.7e-05 22.7 0.0 0.00019 21.2 0.0 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain FBPase PF00316.15 EGC37167.1 - 0.036 12.8 0.3 0.22 10.2 0.1 1.9 2 0 0 2 2 2 0 Fructose-1-6-bisphosphatase Acetyltransf_6 PF13480.1 EGC37167.1 - 0.062 13.2 0.0 0.086 12.7 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF3749 PF12568.3 EGC37167.1 - 0.062 12.8 0.0 0.082 12.5 0.0 1.3 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain DUF1847 PF08901.6 EGC37167.1 - 0.12 11.9 0.0 0.15 11.5 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1847) LIM PF00412.17 EGC37168.1 - 8.3e-26 89.8 25.9 1.3e-14 54.0 4.0 2.1 2 0 0 2 2 2 2 LIM domain Lar_restr_allev PF14354.1 EGC37168.1 - 0.029 14.6 7.5 0.029 14.6 5.2 2.9 2 1 0 2 2 2 0 Restriction alleviation protein Lar zf-DNA_Pol PF08996.5 EGC37168.1 - 0.059 12.7 10.5 0.2 10.9 0.9 2.4 2 0 0 2 2 2 0 DNA Polymerase alpha zinc finger E6 PF00518.12 EGC37168.1 - 0.07 13.4 3.4 0.81 10.0 0.1 2.6 2 0 0 2 2 2 0 Early Protein (E6) Mu-like_Com PF10122.4 EGC37168.1 - 0.23 10.5 0.2 0.23 10.5 0.1 3.2 3 0 0 3 3 3 0 Mu-like prophage protein Com zf-ribbon_3 PF13248.1 EGC37168.1 - 0.56 9.4 20.1 0.82 8.9 0.3 4.3 4 2 0 4 4 4 0 zinc-ribbon domain Elf1 PF05129.8 EGC37168.1 - 1.1 8.9 15.5 0.13 11.9 1.3 3.2 2 1 1 3 3 3 0 Transcription elongation factor Elf1 like zinc_ribbon_2 PF13240.1 EGC37168.1 - 4.3 6.9 24.9 1.7 8.2 0.5 5.1 6 0 0 6 6 6 0 zinc-ribbon domain NOB1_Zn_bind PF08772.6 EGC37168.1 - 4.5 7.1 14.7 2.1 8.2 2.5 3.5 3 0 0 3 3 3 0 Nin one binding (NOB1) Zn-ribbon like BTB_2 PF02214.17 EGC37170.1 - 7.1e-14 51.7 0.0 1.4e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain BTB PF00651.26 EGC37170.1 - 0.027 14.4 0.0 0.049 13.6 0.0 1.4 1 0 0 1 1 1 0 BTB/POZ domain Ricin_B_lectin PF00652.17 EGC37172.1 - 5.3e-13 49.0 0.4 5.3e-13 49.0 0.3 2.2 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EGC37172.1 - 0.0014 18.9 6.7 0.0033 17.7 0.2 3.5 3 0 0 3 3 3 1 Ricin-type beta-trefoil lectin domain-like zf-TRAF PF02176.13 EGC37173.1 - 2.2e-17 63.1 19.3 2.9e-12 46.7 6.7 4.5 3 1 2 5 5 5 2 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC37173.1 - 1.3e-05 25.1 14.6 1.3e-05 25.1 10.1 3.9 2 1 3 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC37173.1 - 0.00018 21.1 11.1 0.00018 21.1 7.7 3.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC37173.1 - 0.00059 19.5 20.8 0.0014 18.3 0.5 3.7 1 1 1 3 3 3 2 Seven in absentia protein family zf-RING_2 PF13639.1 EGC37173.1 - 0.0056 16.4 11.7 0.0056 16.4 8.1 2.8 2 1 0 2 2 2 1 Ring finger domain Actin PF00022.14 EGC37174.1 - 5.2e-76 255.6 0.0 9.3e-76 254.7 0.0 1.4 1 1 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC37174.1 - 0.04 12.5 0.0 0.17 10.4 0.0 2.0 1 1 0 1 1 1 0 MreB/Mbl protein E1-E2_ATPase PF00122.15 EGC37175.1 - 8.1e-31 106.8 0.2 2e-30 105.5 0.1 1.6 1 0 0 1 1 1 1 E1-E2 ATPase HAD PF12710.2 EGC37175.1 - 8e-14 52.2 0.0 2.2e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC37175.1 - 1.8e-12 47.0 0.0 6.9e-12 45.1 0.0 2.0 2 0 0 2 2 2 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase PF00702.21 EGC37175.1 - 4e-10 40.4 1.5 6.8e-07 29.9 0.7 2.6 2 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase DUF3590 PF12148.3 EGC37175.1 - 0.0066 16.0 0.5 0.034 13.7 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF3590) Hydrolase_3 PF08282.7 EGC37175.1 - 0.0068 16.0 0.2 0.0068 16.0 0.1 3.0 4 0 0 4 4 4 1 haloacid dehalogenase-like hydrolase Sex_peptide PF08138.6 EGC37175.1 - 1.3 8.8 3.7 2.7 7.8 0.2 3.1 3 0 0 3 3 3 0 Sex peptide (SP) family Peptidase_M24 PF00557.19 EGC37176.1 - 1.8e-53 181.2 0.2 2.5e-53 180.7 0.1 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGC37176.1 - 1e-29 102.6 0.0 1.8e-29 101.8 0.0 1.4 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain DUF3793 PF12672.2 EGC37176.1 - 0.01 15.4 0.1 0.032 13.8 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3793) EGF_2 PF07974.8 EGC37177.1 - 0.0018 18.3 9.7 0.0036 17.4 6.7 1.5 1 0 0 1 1 1 1 EGF-like domain DUF1191 PF06697.7 EGC37177.1 - 0.1 11.3 0.0 0.17 10.6 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) bZIP_1 PF00170.16 EGC37178.1 - 2.8e-11 43.2 9.6 2.8e-11 43.2 6.6 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGC37178.1 - 2.3e-08 33.7 6.1 2.3e-08 33.7 4.2 3.5 3 1 1 4 4 4 2 Basic region leucine zipper bZIP_Maf PF03131.12 EGC37178.1 - 0.001 19.2 6.3 0.001 19.2 4.4 3.1 3 0 0 3 3 3 1 bZIP Maf transcription factor PBP1_TM PF14812.1 EGC37178.1 - 3.8 7.8 13.6 1.2 9.4 6.7 2.2 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal SurA_N_3 PF13624.1 EGC37180.1 - 0.14 12.1 3.5 0.076 12.9 1.1 1.6 1 1 1 2 2 2 0 SurA N-terminal domain Orbi_NS3 PF01616.11 EGC37180.1 - 0.27 10.2 1.2 0.43 9.5 0.8 1.3 1 0 0 1 1 1 0 Orbivirus NS3 Erf4 PF10256.4 EGC37180.1 - 0.3 10.9 7.6 5.7 6.8 0.0 2.7 2 1 1 3 3 3 0 Golgin subfamily A member 7/ERF4 family DUF1426 PF07234.6 EGC37180.1 - 0.36 10.5 7.0 0.52 10.0 4.8 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF1426) DUF3043 PF11241.3 EGC37180.1 - 5.7 6.4 6.1 8.1 6.0 4.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3043) DUF2207 PF09972.4 EGC37180.1 - 9.6 4.6 13.9 13 4.1 7.9 1.9 1 1 1 2 2 2 0 Predicted membrane protein (DUF2207) ABC2_membrane PF01061.19 EGC37181.1 - 3e-37 127.8 23.6 4.5e-37 127.2 16.4 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC37181.1 - 2.6e-28 99.0 0.1 2.6e-28 99.0 0.0 2.1 2 0 0 2 2 2 1 ABC transporter AAA_21 PF13304.1 EGC37181.1 - 1.8e-11 44.5 18.7 8.9e-10 38.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGC37181.1 - 1e-05 24.7 18.3 1e-05 24.7 12.7 2.5 2 1 0 2 2 1 1 ABC-2 family transporter protein AAA_16 PF13191.1 EGC37181.1 - 0.00012 22.0 0.0 0.00028 20.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain ABC2_membrane_2 PF12679.2 EGC37181.1 - 0.00016 20.6 3.6 0.00029 19.7 2.5 1.4 1 0 0 1 1 1 1 ABC-2 family transporter protein AAA_22 PF13401.1 EGC37181.1 - 0.00037 20.6 0.0 0.00099 19.2 0.0 1.8 1 1 0 1 1 1 1 AAA domain DUF258 PF03193.11 EGC37181.1 - 0.00072 18.7 0.1 0.0014 17.8 0.1 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 PDR_CDR PF06422.7 EGC37181.1 - 0.00073 19.1 0.1 0.0019 17.8 0.1 1.7 1 0 0 1 1 1 1 CDR ABC transporter AAA_25 PF13481.1 EGC37181.1 - 0.0012 18.2 0.0 0.0094 15.3 0.0 2.1 1 1 0 1 1 1 1 AAA domain Thymidylate_kin PF02223.12 EGC37181.1 - 0.0015 17.9 0.0 0.004 16.5 0.0 1.7 1 0 0 1 1 1 1 Thymidylate kinase AAA_17 PF13207.1 EGC37181.1 - 0.0017 19.1 0.0 0.0059 17.4 0.0 2.0 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGC37181.1 - 0.0027 17.2 0.1 0.0067 15.9 0.0 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EGC37181.1 - 0.0027 16.6 0.2 0.0066 15.3 0.1 1.6 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_35 PF14516.1 EGC37181.1 - 0.0035 16.0 0.0 0.0056 15.3 0.0 1.2 1 0 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EGC37181.1 - 0.0056 16.9 6.0 0.0086 16.3 0.0 2.6 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC37181.1 - 0.0089 15.7 0.0 0.053 13.2 0.0 2.1 2 0 0 2 2 2 1 Part of AAA domain ArgK PF03308.11 EGC37181.1 - 0.0092 14.7 0.3 0.019 13.7 0.2 1.4 1 0 0 1 1 1 1 ArgK protein SbcCD_C PF13558.1 EGC37181.1 - 0.01 15.7 0.0 0.056 13.3 0.0 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGC37181.1 - 0.011 15.5 0.0 0.041 13.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGC37181.1 - 0.022 14.6 1.3 0.046 13.6 0.0 2.3 2 0 0 2 2 1 0 AAA domain AAA PF00004.24 EGC37181.1 - 0.022 14.9 0.0 0.14 12.3 0.0 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Linker_histone PF00538.14 EGC37181.1 - 0.03 14.3 0.4 0.085 12.9 0.3 1.7 1 0 0 1 1 1 0 linker histone H1 and H5 family NTPase_1 PF03266.10 EGC37181.1 - 0.043 13.5 0.0 5.9 6.5 0.0 2.6 2 0 0 2 2 2 0 NTPase UPF0079 PF02367.12 EGC37181.1 - 0.047 13.3 0.1 0.1 12.2 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 APS_kinase PF01583.15 EGC37181.1 - 0.067 12.8 0.0 0.13 11.8 0.0 1.4 1 0 0 1 1 1 0 Adenylylsulphate kinase AAA_28 PF13521.1 EGC37181.1 - 0.072 13.0 0.1 0.15 12.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain MobB PF03205.9 EGC37181.1 - 0.17 11.5 1.3 0.26 10.9 0.0 2.0 2 0 0 2 2 1 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_30 PF13604.1 EGC37181.1 - 0.21 11.1 0.0 0.38 10.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain Nup160 PF11715.3 EGC37182.1 - 6.3e-20 70.8 21.1 3.2e-19 68.5 14.7 2.0 1 1 0 1 1 1 1 Nucleoporin Nup120/160 CcmE PF03100.10 EGC37182.1 - 8.4e-14 51.2 0.1 3.2e-13 49.3 0.1 2.0 1 0 0 1 1 1 1 CcmE DUF3098 PF11297.3 EGC37183.1 - 0.11 12.2 4.3 0.12 12.1 0.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3098) DUF4481 PF14800.1 EGC37183.1 - 3.5 6.4 7.6 0.064 12.1 0.3 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4481) AAA_12 PF13087.1 EGC37184.1 - 9e-54 181.8 1.0 5.4e-53 179.3 0.4 2.8 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGC37184.1 - 7e-33 114.1 15.4 3.9e-20 72.4 0.0 4.4 2 2 1 3 3 2 2 AAA domain AAA_30 PF13604.1 EGC37184.1 - 2.5e-08 33.7 0.0 5.2e-08 32.7 0.0 1.5 1 1 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC37184.1 - 6.3e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain PAP_assoc PF03828.14 EGC37184.1 - 1.6e-05 24.7 0.3 5.7e-05 22.9 0.2 2.1 1 0 0 1 1 1 1 Cid1 family poly A polymerase Viral_helicase1 PF01443.13 EGC37184.1 - 2.8e-05 23.7 0.0 0.83 9.1 0.0 3.7 2 1 0 2 2 2 2 Viral (Superfamily 1) RNA helicase NTP_transf_2 PF01909.18 EGC37184.1 - 0.00025 21.3 0.0 0.00025 21.3 0.0 3.5 3 0 0 3 3 3 1 Nucleotidyltransferase domain AAA_22 PF13401.1 EGC37184.1 - 0.00046 20.3 0.0 0.0033 17.5 0.0 2.6 1 0 0 1 1 1 1 AAA domain T2SE PF00437.15 EGC37184.1 - 0.023 13.5 0.0 0.048 12.5 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_25 PF13481.1 EGC37184.1 - 0.2 11.0 0.0 0.42 9.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC37184.1 - 0.36 10.7 0.0 0.89 9.5 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain Oxidored_q3 PF00499.15 EGC37185.1 - 0.015 15.1 2.1 0.018 14.7 1.5 1.1 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Chromo PF00385.19 EGC37186.1 - 1.9e-07 30.6 0.1 2.5e-07 30.2 0.1 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC37186.1 - 0.088 12.5 0.5 0.11 12.2 0.4 1.3 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain PAP2 PF01569.16 EGC37187.1 - 7.8e-19 67.6 4.6 7.8e-19 67.6 3.2 1.7 2 0 0 2 2 2 1 PAP2 superfamily Pex14_N PF04695.8 EGC37187.1 - 0.0095 15.9 1.0 0.016 15.2 0.7 1.4 1 0 0 1 1 1 1 Peroxisomal membrane anchor protein (Pex14p) conserved region FimP PF09766.4 EGC37187.1 - 0.027 13.5 6.9 0.035 13.1 4.8 1.1 1 0 0 1 1 1 0 Fms-interacting protein Neur_chan_memb PF02932.11 EGC37187.1 - 0.11 12.4 0.1 0.11 12.4 0.1 1.8 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region ABC2_membrane_5 PF13346.1 EGC37187.1 - 0.44 9.8 15.5 0.097 11.9 1.2 2.8 2 1 0 2 2 2 0 ABC-2 family transporter protein Acetyltransf_4 PF13420.1 EGC37188.1 - 5.9e-25 88.0 0.0 7.3e-25 87.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC37188.1 - 5.2e-10 39.2 0.0 8e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_3 PF13302.1 EGC37188.1 - 1.1e-05 25.5 0.0 1.4e-05 25.3 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC37188.1 - 5.1e-05 22.9 0.0 7.9e-05 22.3 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_10 PF13673.1 EGC37188.1 - 0.00033 20.7 0.0 0.00043 20.3 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltran PF12746.2 EGC37188.1 - 0.043 12.6 0.0 0.058 12.2 0.0 1.3 1 0 0 1 1 1 0 GNAT acetyltransferase Acetyltransf_7 PF13508.1 EGC37188.1 - 0.054 13.6 0.0 0.095 12.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain AAA PF00004.24 EGC37189.1 - 2.9e-52 176.3 2.0 1.3e-34 119.2 0.0 3.0 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGC37189.1 - 2.6e-12 46.7 3.4 2.6e-05 24.1 0.0 3.6 3 1 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGC37189.1 - 2e-10 40.9 1.6 8.5e-05 22.6 0.0 5.0 3 2 0 3 3 3 2 AAA domain AAA_17 PF13207.1 EGC37189.1 - 7.4e-10 39.7 0.0 0.0028 18.4 0.0 3.0 2 1 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGC37189.1 - 5.5e-09 36.1 0.3 0.0011 18.9 0.0 2.5 2 0 0 2 2 2 2 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGC37189.1 - 3.2e-08 33.7 0.1 0.0015 18.5 0.0 3.0 2 2 0 2 2 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EGC37189.1 - 2.7e-07 30.5 1.5 0.015 15.0 0.1 3.9 2 1 1 3 3 3 1 Archaeal ATPase TIP49 PF06068.8 EGC37189.1 - 3.8e-07 29.1 1.0 8.2e-05 21.4 0.1 3.1 3 0 0 3 3 3 1 TIP49 C-terminus AAA_33 PF13671.1 EGC37189.1 - 6.6e-07 29.2 0.0 0.0071 16.2 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EGC37189.1 - 1.7e-06 27.2 0.0 0.00039 19.5 0.0 2.7 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus Zeta_toxin PF06414.7 EGC37189.1 - 1.7e-06 27.2 0.1 0.0058 15.7 0.0 2.3 2 0 0 2 2 2 2 Zeta toxin AAA_28 PF13521.1 EGC37189.1 - 8.4e-06 25.8 0.0 0.059 13.3 0.0 2.3 2 0 0 2 2 2 2 AAA domain IstB_IS21 PF01695.12 EGC37189.1 - 1.2e-05 24.8 0.0 0.00017 21.0 0.0 2.3 2 0 0 2 2 2 1 IstB-like ATP binding protein ABC_tran PF00005.22 EGC37189.1 - 1.6e-05 25.1 3.1 0.01 16.1 0.1 3.0 3 0 0 3 3 2 2 ABC transporter AAA_19 PF13245.1 EGC37189.1 - 2.3e-05 24.0 0.1 0.011 15.5 0.0 2.5 2 0 0 2 2 2 1 Part of AAA domain RNA_helicase PF00910.17 EGC37189.1 - 2.5e-05 24.4 0.9 0.26 11.4 0.0 4.0 4 0 0 4 4 4 2 RNA helicase AAA_5 PF07728.9 EGC37189.1 - 2.5e-05 24.0 0.1 0.0021 17.7 0.0 3.1 2 2 0 2 2 2 1 AAA domain (dynein-related subfamily) Mg_chelatase PF01078.16 EGC37189.1 - 2.7e-05 23.4 0.1 0.0018 17.4 0.0 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI DUF815 PF05673.8 EGC37189.1 - 5.2e-05 22.2 0.1 0.023 13.6 0.0 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF815) NACHT PF05729.7 EGC37189.1 - 8.7e-05 22.2 1.6 0.061 12.9 0.0 3.9 3 2 2 5 5 4 1 NACHT domain AAA_29 PF13555.1 EGC37189.1 - 9.9e-05 21.7 0.2 0.037 13.5 0.0 3.0 3 0 0 3 3 3 1 P-loop containing region of AAA domain T2SE PF00437.15 EGC37189.1 - 0.00022 20.2 0.0 0.11 11.3 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_25 PF13481.1 EGC37189.1 - 0.00053 19.4 1.2 1.5 8.2 0.0 3.7 3 1 0 4 4 4 1 AAA domain AAA_24 PF13479.1 EGC37189.1 - 0.00053 19.6 0.1 0.093 12.2 0.0 2.9 2 0 0 2 2 2 1 AAA domain AAA_11 PF13086.1 EGC37189.1 - 0.0012 18.5 0.1 0.015 14.8 0.0 2.3 2 0 0 2 2 2 1 AAA domain PPV_E1_C PF00519.12 EGC37189.1 - 0.0015 17.2 0.1 0.31 9.5 0.0 2.4 2 0 0 2 2 2 1 Papillomavirus helicase MobB PF03205.9 EGC37189.1 - 0.0016 18.1 0.0 1.2 8.8 0.0 2.9 2 1 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B Sigma54_activat PF00158.21 EGC37189.1 - 0.0022 17.5 0.1 0.0081 15.6 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_18 PF13238.1 EGC37189.1 - 0.009 16.3 11.8 0.46 10.7 0.0 3.8 4 1 0 4 4 2 2 AAA domain AAA_30 PF13604.1 EGC37189.1 - 0.015 14.8 0.0 1.1 8.8 0.0 2.2 2 0 0 2 2 2 0 AAA domain UPF0079 PF02367.12 EGC37189.1 - 0.017 14.7 0.2 10 5.7 0.0 2.8 3 0 0 3 3 2 0 Uncharacterised P-loop hydrolase UPF0079 PhoH PF02562.11 EGC37189.1 - 0.019 14.1 0.0 0.057 12.6 0.0 1.8 1 0 0 1 1 1 0 PhoH-like protein Sigma54_activ_2 PF14532.1 EGC37189.1 - 0.023 14.7 0.1 0.13 12.3 0.0 2.2 3 0 0 3 3 1 0 Sigma-54 interaction domain KaiC PF06745.8 EGC37189.1 - 0.029 13.5 3.2 0.66 9.0 0.1 4.0 3 1 1 4 4 4 0 KaiC ATP-synt_ab PF00006.20 EGC37189.1 - 0.034 13.6 0.1 2 7.8 0.0 2.4 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain CPT PF07931.7 EGC37189.1 - 0.044 13.4 0.0 5.1 6.6 0.0 2.3 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein NTPase_1 PF03266.10 EGC37189.1 - 0.071 12.8 0.4 15 5.2 0.0 3.4 4 0 0 4 4 3 0 NTPase DUF258 PF03193.11 EGC37189.1 - 0.078 12.1 0.1 5.3 6.2 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 SKI PF01202.17 EGC37189.1 - 0.082 12.7 0.0 3.1 7.6 0.0 3.1 3 0 0 3 3 3 0 Shikimate kinase AAA_3 PF07726.6 EGC37189.1 - 0.085 12.4 0.0 0.45 10.1 0.0 2.3 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) SEO_C PF14577.1 EGC37190.1 - 0.28 10.4 3.2 3.4 6.9 1.6 2.1 1 1 1 2 2 2 0 Sieve element occlusion C-terminus WD40 PF00400.27 EGC37192.1 - 1.3e-09 37.5 13.9 0.0081 16.0 0.0 5.3 5 1 0 5 5 5 3 WD domain, G-beta repeat DNA_pol_E_B PF04042.11 EGC37193.1 - 2.6e-43 147.7 0.7 2.6e-43 147.7 0.5 1.6 2 0 0 2 2 2 1 DNA polymerase alpha/epsilon subunit B Dpoe2NT PF12213.3 EGC37193.1 - 1.8e-09 37.3 0.8 5.3e-09 35.8 0.3 2.0 2 0 0 2 2 2 1 DNA polymerases epsilon N terminal Pkinase_Tyr PF07714.12 EGC37194.1 - 7.9e-52 175.8 0.0 1.1e-51 175.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC37194.1 - 7.4e-48 162.9 0.0 1.3e-47 162.1 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain DEAD PF00270.24 EGC37195.1 - 8.1e-43 145.8 0.1 1.6e-41 141.5 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC37195.1 - 2.5e-26 91.3 0.1 1e-25 89.4 0.1 2.1 1 0 0 1 1 1 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGC37195.1 - 4e-05 22.5 0.0 6.1e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 SNF2 family N-terminal domain DUF1253 PF06862.7 EGC37195.1 - 0.00011 20.7 0.0 0.00094 17.6 0.0 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF1253) ResIII PF04851.10 EGC37195.1 - 0.027 14.3 0.0 0.085 12.6 0.0 1.9 1 0 0 1 1 1 0 Type III restriction enzyme, res subunit Kelch_4 PF13418.1 EGC37196.1 - 4.4e-51 170.4 24.9 1.5e-10 40.6 1.6 6.1 5 1 1 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC37196.1 - 1.7e-50 168.1 12.8 9e-10 38.4 0.0 6.5 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC37196.1 - 7.9e-46 153.3 7.3 8.5e-09 34.8 0.0 6.1 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC37196.1 - 2.2e-43 144.6 15.7 8.9e-09 35.1 0.0 6.1 3 1 3 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC37196.1 - 1.4e-42 143.0 11.5 2.2e-08 33.8 0.0 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC37196.1 - 1.4e-41 138.7 13.7 4.6e-06 26.1 0.8 6.1 6 0 0 6 6 6 6 Kelch motif PQQ_3 PF13570.1 EGC37196.1 - 0.011 15.9 5.4 34 4.8 0.0 5.3 5 1 0 5 5 5 0 PQQ-like domain TMEM223 PF14640.1 EGC37197.1 - 0.1 12.5 0.1 0.1 12.5 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 223 Secretin_N_2 PF07655.8 EGC37197.1 - 1.5 9.2 9.1 2.4 8.6 6.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain FKBP_C PF00254.23 EGC37198.1 - 2.2e-19 69.2 0.0 5.1e-19 68.0 0.0 1.6 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase TPR_11 PF13414.1 EGC37198.1 - 1.9e-15 56.2 0.8 3.9e-10 39.2 0.1 2.5 1 1 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGC37198.1 - 1.7e-10 40.0 1.0 0.0049 16.4 0.0 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC37198.1 - 4.9e-10 38.5 0.9 0.0021 17.8 0.0 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37198.1 - 3.7e-07 29.9 0.1 3.1e-06 27.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37198.1 - 9e-07 28.2 0.8 0.016 14.9 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37198.1 - 0.00018 21.8 0.1 0.0075 16.5 0.0 2.8 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC37198.1 - 0.00073 19.5 0.3 0.026 14.7 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC37198.1 - 0.0014 18.9 0.3 8.4 7.1 0.1 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC37198.1 - 0.0018 17.9 0.4 0.23 11.3 0.0 3.1 3 0 0 3 3 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC37198.1 - 0.0047 17.0 3.1 0.12 12.4 0.0 2.9 1 1 1 2 2 2 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGC37198.1 - 0.065 13.9 0.0 1.8 9.4 0.0 2.5 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37198.1 - 0.11 13.2 0.0 0.8 10.4 0.0 2.2 2 0 0 2 2 2 0 Tetratricopeptide repeat Ubiquitin_2 PF14560.1 EGC37199.1 - 1.4e-26 92.5 0.3 2.8e-26 91.5 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin-like domain CAP_GLY PF01302.20 EGC37199.1 - 5.3e-25 86.9 0.1 9.6e-25 86.0 0.1 1.4 1 0 0 1 1 1 1 CAP-Gly domain DUF3244 PF11589.3 EGC37199.1 - 0.08 12.6 0.4 0.16 11.6 0.3 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3244) Mito_carr PF00153.22 EGC37201.1 - 6.9e-68 224.4 2.5 6.8e-22 76.9 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein Citrate_synt PF00285.16 EGC37202.1 - 5.7e-24 84.5 0.0 1.2e-20 73.5 0.0 2.8 1 1 1 2 2 2 2 Citrate synthase Ligase_CoA PF00549.14 EGC37202.1 - 4e-10 39.4 0.1 2.2e-09 37.0 0.0 2.1 2 0 0 2 2 2 1 CoA-ligase Succ_CoA_lig PF13607.1 EGC37202.1 - 0.00063 19.3 0.0 0.014 15.0 0.0 2.6 2 0 0 2 2 2 1 Succinyl-CoA ligase like flavodoxin domain CoA_binding PF02629.14 EGC37202.1 - 0.00077 19.9 0.0 0.0019 18.6 0.0 1.8 1 0 0 1 1 1 1 CoA binding domain SapB_1 PF05184.10 EGC37203.1 - 0.00075 19.2 0.5 0.0019 17.9 0.3 1.7 1 0 0 1 1 1 1 Saposin-like type B, region 1 Toxin-deaminase PF14424.1 EGC37203.1 - 0.006 16.5 0.0 0.009 15.9 0.0 1.2 1 0 0 1 1 1 1 The BURPS668_1122 family of deaminases RRM_1 PF00076.17 EGC37204.1 - 3e-18 65.2 0.1 4.5e-18 64.6 0.1 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37204.1 - 4e-15 55.5 0.1 6.6e-15 54.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37204.1 - 2.4e-07 30.4 0.2 5.1e-07 29.4 0.0 1.6 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC37204.1 - 0.00033 20.4 0.0 0.00053 19.8 0.0 1.3 1 0 0 1 1 1 1 RNA binding motif PEP-utilisers_N PF05524.8 EGC37205.1 - 9.2 6.0 14.9 4.2 7.1 1.1 3.8 2 2 1 3 3 3 0 PEP-utilising enzyme, N-terminal Tropomyosin_1 PF12718.2 EGC37206.1 - 0.00042 20.1 22.5 0.00042 20.1 15.6 4.5 3 1 1 4 4 4 1 Tropomyosin like Reo_sigmaC PF04582.7 EGC37206.1 - 0.0028 16.8 4.7 0.0028 16.8 3.3 3.7 3 1 0 4 4 4 2 Reovirus sigma C capsid protein CALCOCO1 PF07888.6 EGC37206.1 - 0.0028 16.0 24.3 0.0028 16.0 16.9 2.9 2 2 1 3 3 3 1 Calcium binding and coiled-coil domain (CALCOCO1) like CENP-F_leu_zip PF10473.4 EGC37206.1 - 0.0079 16.0 29.1 0.0079 16.0 20.2 4.7 3 1 1 4 4 4 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Sec20 PF03908.8 EGC37206.1 - 0.014 15.0 1.7 0.014 15.0 1.2 5.5 4 1 2 6 6 6 0 Sec20 DUF904 PF06005.7 EGC37206.1 - 0.019 15.2 1.8 0.019 15.2 1.3 6.9 4 2 1 5 5 5 0 Protein of unknown function (DUF904) HSBP1 PF06825.7 EGC37206.1 - 0.058 12.9 0.4 0.058 12.9 0.3 4.7 5 0 0 5 5 5 0 Heat shock factor binding protein 1 HasA PF06438.7 EGC37206.1 - 0.082 12.2 0.1 0.2 11.0 0.0 1.7 1 0 0 1 1 1 0 Heme-binding protein A (HasA) MbeD_MobD PF04899.7 EGC37206.1 - 0.092 12.6 8.4 4.4 7.2 0.0 4.8 4 1 2 6 6 6 0 MbeD/MobD like IncA PF04156.9 EGC37206.1 - 0.31 10.6 64.3 2.7 7.5 0.1 4.9 3 1 1 4 4 4 0 IncA protein DUF4419 PF14388.1 EGC37207.1 - 2.7e-10 39.9 2.4 4.1e-07 29.4 0.1 2.6 2 1 1 3 3 3 2 Domain of unknown function (DUF4419) ATP-synt_8 PF00895.15 EGC37207.1 - 0.097 12.8 2.0 0.17 12.0 0.2 2.3 2 0 0 2 2 2 0 ATP synthase protein 8 Arf PF00025.16 EGC37208.1 - 3.7e-24 84.9 0.0 4.6e-24 84.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC37208.1 - 4.8e-08 33.5 0.0 6.9e-08 33.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC37208.1 - 4e-06 26.7 0.5 0.00014 21.7 0.3 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC37208.1 - 4e-06 26.1 0.6 1.2e-05 24.6 0.4 1.6 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MobB PF03205.9 EGC37208.1 - 0.00064 19.4 0.1 0.0013 18.4 0.1 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B Arch_ATPase PF01637.13 EGC37208.1 - 0.0022 17.7 0.1 0.0034 17.1 0.0 1.2 1 0 0 1 1 1 1 Archaeal ATPase cobW PF02492.14 EGC37208.1 - 0.0075 15.7 0.1 0.18 11.2 0.1 2.1 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain Ras PF00071.17 EGC37208.1 - 0.018 14.4 0.3 0.15 11.4 0.2 2.0 1 1 0 1 1 1 0 Ras family AAA_14 PF13173.1 EGC37208.1 - 0.027 14.3 0.1 0.086 12.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGC37208.1 - 0.049 13.0 0.3 2.3 7.6 0.1 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain FeoB_N PF02421.13 EGC37208.1 - 0.13 11.5 0.2 0.46 9.7 0.0 1.9 2 0 0 2 2 2 0 Ferrous iron transport protein B Lon_C PF05362.8 EGC37209.1 - 4.1e-61 205.8 0.0 7.7e-61 204.9 0.0 1.4 1 0 0 1 1 1 1 Lon protease (S16) C-terminal proteolytic domain AAA PF00004.24 EGC37209.1 - 1.4e-24 86.7 0.1 6.9e-24 84.5 0.0 2.2 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGC37209.1 - 3.4e-10 40.0 0.0 9.6e-10 38.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) LON PF02190.11 EGC37209.1 - 1.8e-09 37.6 0.6 6.2e-09 35.8 0.1 2.2 2 0 0 2 2 1 1 ATP-dependent protease La (LON) domain AAA_5 PF07728.9 EGC37209.1 - 9.5e-09 35.1 0.0 2e-08 34.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) ChlI PF13541.1 EGC37209.1 - 4.6e-08 32.6 0.1 1.2e-07 31.2 0.0 1.8 2 0 0 2 2 1 1 Subunit ChlI of Mg-chelatase AAA_17 PF13207.1 EGC37209.1 - 8.4e-06 26.6 0.0 3.3e-05 24.6 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_PrkA PF08298.6 EGC37209.1 - 2.5e-05 23.1 0.0 6.6e-05 21.7 0.0 1.7 1 0 0 1 1 1 1 PrkA AAA domain AAA_22 PF13401.1 EGC37209.1 - 6.2e-05 23.1 0.3 0.0033 17.5 0.2 2.7 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC37209.1 - 8.1e-05 22.6 0.1 0.00035 20.6 0.0 2.1 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EGC37209.1 - 8.1e-05 21.5 0.9 0.015 14.0 0.1 2.5 2 0 0 2 2 2 1 TIP49 C-terminus AAA_14 PF13173.1 EGC37209.1 - 0.00017 21.4 4.5 0.00025 20.9 0.0 3.0 3 0 0 3 3 3 1 AAA domain AAA_3 PF07726.6 EGC37209.1 - 0.00041 19.9 0.0 0.001 18.6 0.0 1.7 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RNA_helicase PF00910.17 EGC37209.1 - 0.0025 17.9 0.0 0.0074 16.4 0.0 1.9 1 0 0 1 1 1 1 RNA helicase AAA_19 PF13245.1 EGC37209.1 - 0.0028 17.3 0.0 0.008 15.9 0.0 1.7 1 0 0 1 1 1 1 Part of AAA domain ATP-synt_ab PF00006.20 EGC37209.1 - 0.0036 16.8 0.0 0.0057 16.1 0.0 1.4 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain Parvo_NS1 PF01057.12 EGC37209.1 - 0.0042 16.0 0.0 0.012 14.4 0.0 1.7 1 0 0 1 1 1 1 Parvovirus non-structural protein NS1 RuvB_N PF05496.7 EGC37209.1 - 0.0042 16.1 0.0 0.011 14.8 0.0 1.7 1 1 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGC37209.1 - 0.0065 16.7 0.1 0.0065 16.7 0.1 2.8 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC37209.1 - 0.0072 15.7 0.1 0.023 14.0 0.1 1.8 1 0 0 1 1 1 1 AAA domain MobB PF03205.9 EGC37209.1 - 0.0073 16.0 0.4 0.021 14.5 0.0 1.9 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B IstB_IS21 PF01695.12 EGC37209.1 - 0.01 15.2 0.0 0.025 13.9 0.0 1.6 1 0 0 1 1 1 0 IstB-like ATP binding protein SKI PF01202.17 EGC37209.1 - 0.019 14.8 0.4 2.7 7.8 0.1 3.8 4 0 0 4 4 4 0 Shikimate kinase NACHT PF05729.7 EGC37209.1 - 0.043 13.4 0.0 0.23 11.1 0.0 2.2 2 0 0 2 2 2 0 NACHT domain AAA_33 PF13671.1 EGC37209.1 - 0.044 13.6 0.0 0.082 12.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC37209.1 - 0.052 13.8 2.9 0.085 13.1 0.0 2.5 2 0 0 2 2 2 0 ABC transporter NTPase_1 PF03266.10 EGC37209.1 - 0.053 13.2 1.9 0.18 11.4 0.0 2.6 2 1 1 3 3 2 0 NTPase Mg_chelatase PF01078.16 EGC37209.1 - 0.062 12.4 0.0 0.18 10.9 0.0 1.7 2 0 0 2 2 1 0 Magnesium chelatase, subunit ChlI UPF0079 PF02367.12 EGC37209.1 - 0.069 12.7 0.0 0.3 10.7 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EGC37209.1 - 0.078 12.9 0.1 0.17 11.8 0.1 1.5 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC37209.1 - 0.085 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_10 PF12846.2 EGC37209.1 - 0.12 11.7 0.8 2.3 7.5 0.0 2.2 2 0 0 2 2 2 0 AAA-like domain AAA_24 PF13479.1 EGC37209.1 - 0.13 11.7 2.3 0.14 11.6 0.2 2.0 2 0 0 2 2 2 0 AAA domain AAA_11 PF13086.1 EGC37209.1 - 7.6 6.0 7.8 1.2 8.6 0.0 2.9 3 0 0 3 3 3 0 AAA domain Pkinase_Tyr PF07714.12 EGC37210.1 - 9e-57 192.0 0.0 1.3e-56 191.5 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC37210.1 - 3.2e-56 190.3 0.0 6.5e-56 189.3 0.0 1.5 1 0 0 1 1 1 1 Protein kinase domain Adipogenin PF15202.1 EGC37210.1 - 2.5 8.0 4.1 5.5 6.9 2.8 1.5 1 0 0 1 1 1 0 Adipogenin SKG6 PF08693.5 EGC37210.1 - 3.3 7.0 6.2 9 5.7 4.3 1.7 1 0 0 1 1 1 0 Transmembrane alpha-helix domain GST_N_3 PF13417.1 EGC37212.1 - 4e-19 68.6 0.1 6.3e-19 67.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC37212.1 - 5.1e-15 55.2 0.0 9e-15 54.4 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC37212.1 - 6.5e-15 55.0 0.0 1.5e-14 53.9 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC37212.1 - 3.6e-06 26.8 0.0 5.8e-06 26.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC37212.1 - 0.0036 17.1 0.0 0.0052 16.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain Glutaredoxin PF00462.19 EGC37212.1 - 0.017 15.1 0.0 0.03 14.3 0.0 1.5 1 0 0 1 1 1 0 Glutaredoxin GST_C_3 PF14497.1 EGC37212.1 - 0.019 15.4 0.0 0.039 14.4 0.0 1.5 1 1 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Methyltransf_18 PF12847.2 EGC37214.1 - 2.4e-07 31.3 0.0 5.2e-07 30.2 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC37214.1 - 3.1e-06 27.0 0.0 7.3e-06 25.7 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGC37214.1 - 7.8e-06 25.1 0.1 5.7e-05 22.3 0.0 2.1 2 0 0 2 2 2 1 Tellurite resistance protein TehB Methyltransf_31 PF13847.1 EGC37214.1 - 0.00021 20.8 0.1 0.00056 19.5 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Rhodanese PF00581.15 EGC37214.1 - 0.00032 21.0 0.0 0.00086 19.6 0.0 1.7 1 0 0 1 1 1 1 Rhodanese-like domain Methyltransf_26 PF13659.1 EGC37214.1 - 0.00036 20.5 0.0 0.0067 16.4 0.0 2.2 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37214.1 - 0.0028 17.9 0.0 0.0063 16.8 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC37214.1 - 0.0041 17.5 0.0 0.013 16.0 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain TPMT PF05724.6 EGC37214.1 - 0.041 13.3 0.0 0.66 9.3 0.0 2.3 2 1 1 3 3 3 0 Thiopurine S-methyltransferase (TPMT) Methyltransf_12 PF08242.7 EGC37214.1 - 0.82 10.1 5.9 2.6 8.5 0.1 3.4 2 1 0 2 2 2 0 Methyltransferase domain ATP_bind_4 PF01902.12 EGC37215.1 - 2.5e-38 131.6 0.0 7.3e-38 130.1 0.0 1.6 1 1 0 1 1 1 1 ATP-binding region P22_AR_C PF10548.4 EGC37215.1 - 0.00051 19.8 0.1 0.013 15.3 0.0 2.7 3 0 0 3 3 3 1 P22AR C-terminal domain HCaRG PF07258.9 EGC37215.1 - 0.045 13.3 0.2 0.12 11.8 0.0 1.7 2 0 0 2 2 2 0 HCaRG protein SPC12 PF06645.8 EGC37216.1 - 2.8e-26 91.1 2.0 3.1e-26 90.9 1.4 1.0 1 0 0 1 1 1 1 Microsomal signal peptidase 12 kDa subunit (SPC12) LtrA PF06772.6 EGC37216.1 - 0.0087 15.0 0.4 0.0094 14.8 0.3 1.0 1 0 0 1 1 1 1 Bacterial low temperature requirement A protein (LtrA) DUF4203 PF13886.1 EGC37216.1 - 0.0096 15.3 0.3 0.011 15.1 0.2 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4203) SdpI PF13630.1 EGC37216.1 - 0.013 15.2 1.6 0.017 14.8 1.1 1.1 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF318 PF03773.8 EGC37216.1 - 0.014 14.3 0.8 0.017 14.1 0.5 1.1 1 0 0 1 1 1 0 Predicted permease ATP_synt_I PF03899.10 EGC37216.1 - 0.068 13.3 1.9 0.081 13.0 1.3 1.1 1 0 0 1 1 1 0 ATP synthase I chain DUF1673 PF07895.6 EGC37216.1 - 0.12 11.8 0.7 0.14 11.6 0.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) TraB PF01963.12 EGC37218.1 - 3.6e-23 82.3 0.0 1.1e-22 80.7 0.0 1.7 1 1 0 1 1 1 1 TraB family SapB_1 PF05184.10 EGC37218.1 - 0.9 9.4 4.0 10 6.0 0.5 3.4 1 1 1 2 2 2 0 Saposin-like type B, region 1 Acatn PF13000.2 EGC37219.1 - 2.4e-120 402.6 30.3 2.3e-93 313.6 11.7 2.1 1 1 1 2 2 2 2 Acetyl-coenzyme A transporter 1 Methyltransf_23 PF13489.1 EGC37220.1 - 2.8e-09 36.9 0.0 5.7e-09 35.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC37220.1 - 3.2e-09 37.3 0.0 2.9e-08 34.2 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC37220.1 - 1.5e-08 34.9 8.2 1.2e-06 28.8 0.0 3.2 3 1 1 4 4 4 2 Methyltransferase domain Methyltransf_31 PF13847.1 EGC37220.1 - 9.9e-08 31.7 0.1 3.7e-07 29.8 0.1 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC37220.1 - 3.8e-05 24.1 0.0 0.00014 22.3 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37220.1 - 0.0023 18.2 0.1 0.015 15.6 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain DUF106 PF01956.11 EGC37221.1 - 1.5e-51 174.2 2.4 1.5e-51 174.2 1.6 1.9 2 0 0 2 2 2 1 Integral membrane protein DUF106 ATP-grasp_2 PF08442.5 EGC37222.1 - 7.3e-16 58.1 0.0 1.1e-15 57.5 0.0 1.2 1 0 0 1 1 1 1 ATP-grasp domain WD40 PF00400.27 EGC37223.1 - 8.7e-45 149.0 6.6 1.2e-10 40.7 0.3 6.4 6 0 0 6 6 6 6 WD domain, G-beta repeat Nup160 PF11715.3 EGC37223.1 - 2.3e-08 32.6 2.2 0.0064 14.6 0.5 4.1 1 1 3 4 4 4 4 Nucleoporin Nup120/160 Cytochrom_D1 PF02239.11 EGC37223.1 - 0.003 15.9 0.0 0.95 7.6 0.0 3.1 3 1 0 3 3 3 1 Cytochrome D1 heme domain PQQ_2 PF13360.1 EGC37223.1 - 0.12 11.8 0.0 2.6 7.4 0.0 2.8 1 1 0 1 1 1 0 PQQ-like domain Lactamase_B PF00753.22 EGC37224.1 - 7.3e-16 58.3 2.3 1.3e-15 57.5 1.6 1.4 1 0 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC37224.1 - 2e-07 30.7 0.9 7.7e-07 28.8 0.6 2.0 1 1 0 1 1 1 1 Beta-lactamase superfamily domain RCC1 PF00415.13 EGC37225.1 - 1.3e-68 227.0 1.2 7.5e-14 51.6 0.2 7.7 8 0 0 8 8 8 6 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC37225.1 - 1.6e-44 148.6 14.3 6.1e-10 38.4 0.0 7.5 7 0 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat Kelch_4 PF13418.1 EGC37225.1 - 1.7 8.4 10.4 4.4 7.1 0.1 4.3 5 0 0 5 5 5 0 Galactose oxidase, central domain SUKH-3 PF14433.1 EGC37225.1 - 6.9 6.4 7.1 11 5.8 0.1 3.3 4 0 0 4 4 4 0 SUKH-3 immunity protein BRO1 PF03097.13 EGC37226.1 - 1.8e-28 99.3 0.1 5e-28 97.9 0.0 1.6 1 1 0 1 1 1 1 BRO1-like domain DUF1751 PF08551.5 EGC37228.1 - 2.5e-21 75.8 9.5 2.5e-21 75.8 6.6 2.2 2 1 1 3 3 3 1 Eukaryotic integral membrane protein (DUF1751) Rhomboid PF01694.17 EGC37228.1 - 1.7e-06 28.0 15.1 1.7e-06 28.0 10.5 1.6 1 1 0 1 1 1 1 Rhomboid family Pkinase_Tyr PF07714.12 EGC37230.1 - 2.1e-53 181.0 0.1 3.9e-53 180.1 0.1 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC37230.1 - 2.1e-51 174.5 0.6 2.1e-51 174.5 0.4 2.5 2 0 0 2 2 2 1 Protein kinase domain CybS PF05328.7 EGC37231.1 - 7.1e-08 32.1 0.1 8.6e-08 31.8 0.1 1.2 1 0 0 1 1 1 1 CybS Cullin PF00888.17 EGC37232.1 - 2.4e-127 425.9 30.2 2.4e-127 425.9 20.9 1.7 2 0 0 2 2 2 1 Cullin family Cullin_Nedd8 PF10557.4 EGC37232.1 - 2.3e-26 91.3 0.6 6.7e-26 89.9 0.4 1.9 1 0 0 1 1 1 1 Cullin protein neddylation domain GAT PF03127.9 EGC37232.1 - 0.26 11.2 4.9 9.1 6.3 0.1 3.7 4 0 0 4 4 4 0 GAT domain DUF3417 PF11897.3 EGC37233.1 - 0.014 15.3 0.4 0.033 14.1 0.3 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3417) MitoNEET_N PF10660.4 EGC37233.1 - 0.039 13.8 0.0 0.19 11.6 0.0 2.1 2 0 0 2 2 2 0 Iron-containing outer mitochondrial membrane protein N-terminus Kelch_4 PF13418.1 EGC37235.1 - 9.5e-18 63.7 5.6 2.8e-07 30.2 0.1 6.1 6 0 0 6 6 6 3 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC37235.1 - 8.1e-17 60.8 5.8 0.00074 19.6 0.3 7.2 8 0 0 8 8 8 3 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC37235.1 - 2.1e-14 53.1 4.5 5.7e-05 22.9 0.1 4.5 4 0 0 4 4 4 3 Kelch motif Kelch_1 PF01344.20 EGC37235.1 - 5.3e-11 41.8 2.0 0.0031 17.0 0.1 5.4 5 0 0 5 5 5 3 Kelch motif Kelch_6 PF13964.1 EGC37235.1 - 2.8e-10 39.8 8.4 0.046 13.8 0.1 5.5 4 1 1 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EGC37235.1 - 8.9e-05 22.1 4.5 0.051 13.3 0.1 4.8 5 0 0 5 5 5 1 Kelch motif FNIP PF05725.7 EGC37236.1 - 2.1e-107 350.8 31.5 1.6e-15 56.7 0.1 7.5 4 2 5 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC37236.1 - 1.5e-09 37.6 11.6 0.49 10.3 0.1 8.3 4 3 5 9 9 9 6 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC37236.1 - 2.6e-09 36.8 0.0 0.00023 20.8 0.0 3.1 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) CBS PF00571.23 EGC37237.1 - 3.7e-27 93.8 0.8 3.1e-07 30.0 0.1 4.3 4 0 0 4 4 4 4 CBS domain Gag_p17 PF00540.13 EGC37238.1 - 0.12 12.1 0.8 0.14 11.9 0.5 1.0 1 0 0 1 1 1 0 gag gene protein p17 (matrix protein) DASH_Dad3 PF08656.5 EGC37238.1 - 0.38 10.4 4.5 0.81 9.4 2.7 1.8 1 1 1 2 2 2 0 DASH complex subunit Dad3 EXS PF03124.9 EGC37239.1 - 1.2e-62 211.9 42.9 1.2e-62 211.9 29.8 1.8 1 1 1 2 2 2 1 EXS family ACT_4 PF13291.1 EGC37239.1 - 0.39 11.0 8.1 0.92 9.8 5.6 1.6 1 0 0 1 1 1 0 ACT domain LCM PF04072.9 EGC37241.1 - 2.9e-24 85.6 0.0 4e-24 85.1 0.0 1.2 1 0 0 1 1 1 1 Leucine carboxyl methyltransferase CReP_N PF10472.4 EGC37241.1 - 0.13 10.9 0.0 0.17 10.5 0.0 1.1 1 0 0 1 1 1 0 eIF2-alpha phosphatase phosphorylation constitutive repressor RNA_pol_Rpb2_6 PF00562.23 EGC37242.1 - 1.5e-128 428.7 0.2 6.7e-128 426.6 0.0 2.0 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGC37242.1 - 1.1e-68 230.1 0.3 1.8e-68 229.5 0.2 1.3 1 0 0 1 1 1 1 RNA polymerase beta subunit RNA_pol_Rpb2_2 PF04561.9 EGC37242.1 - 1.3e-50 171.5 0.0 2.5e-50 170.5 0.0 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_7 PF04560.15 EGC37242.1 - 1e-30 105.8 0.0 2.5e-30 104.5 0.0 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_4 PF04566.8 EGC37242.1 - 4.7e-25 87.1 0.1 1.2e-24 85.8 0.1 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGC37242.1 - 1.6e-23 82.1 0.1 3.4e-23 81.1 0.1 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGC37242.1 - 1e-22 79.8 3.1 2.1e-22 78.7 2.2 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Imm14 PF15428.1 EGC37242.1 - 0.047 14.1 0.0 0.16 12.3 0.0 1.9 1 0 0 1 1 1 0 Immunity protein 14 dCMP_cyt_deam_1 PF00383.17 EGC37243.1 - 6e-13 48.3 0.5 8.4e-13 47.8 0.3 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region Bd3614-deam PF14439.1 EGC37243.1 - 0.00072 19.4 0.3 0.39 10.5 0.1 2.3 1 1 1 2 2 2 2 Bd3614-like deaminase HTH_23 PF13384.1 EGC37244.1 - 7.5e-06 25.4 0.0 1.2e-05 24.7 0.0 1.3 1 0 0 1 1 1 1 Homeodomain-like domain HTH_29 PF13551.1 EGC37244.1 - 1.3e-05 25.2 0.0 1.7e-05 24.9 0.0 1.1 1 0 0 1 1 1 1 Winged helix-turn helix HTH_28 PF13518.1 EGC37244.1 - 0.00016 21.6 0.2 0.00023 21.0 0.1 1.2 1 0 0 1 1 1 1 Helix-turn-helix domain PAX PF00292.13 EGC37244.1 - 0.00033 20.3 0.0 0.00042 20.0 0.0 1.2 1 0 0 1 1 1 1 'Paired box' domain HTH_38 PF13936.1 EGC37244.1 - 0.0043 16.5 0.0 0.0082 15.6 0.0 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain MarR PF01047.17 EGC37244.1 - 0.0077 15.9 0.1 0.01 15.5 0.0 1.3 1 0 0 1 1 1 1 MarR family Fe_dep_repress PF01325.14 EGC37244.1 - 0.008 16.1 0.1 0.011 15.6 0.0 1.3 1 0 0 1 1 1 1 Iron dependent repressor, N-terminal DNA binding domain HTH_36 PF13730.1 EGC37244.1 - 0.0087 16.1 0.4 0.014 15.4 0.2 1.4 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EGC37244.1 - 0.011 15.4 0.1 0.015 15.0 0.1 1.2 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB DUF603 PF04645.7 EGC37244.1 - 0.012 15.5 0.0 0.014 15.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF603 HTH_24 PF13412.1 EGC37244.1 - 0.028 13.7 0.1 0.057 12.8 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Sigma70_r4_2 PF08281.7 EGC37244.1 - 0.069 12.6 0.1 0.1 12.0 0.0 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_AsnC-type PF13404.1 EGC37244.1 - 0.074 12.5 0.0 0.12 11.8 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain MCD PF05292.6 EGC37245.1 - 1.1e-47 162.4 0.1 5.1e-27 94.4 0.0 2.2 1 1 1 2 2 2 2 Malonyl-CoA decarboxylase (MCD) RWD PF05773.17 EGC37245.1 - 0.02 14.7 0.2 0.83 9.5 0.0 2.8 2 0 0 2 2 2 0 RWD domain Snf7 PF03357.16 EGC37246.1 - 1.8e-28 99.0 24.8 1.8e-28 99.0 17.2 1.5 1 1 1 2 2 2 1 Snf7 PHA-1 PF06542.6 EGC37246.1 - 0.029 13.0 3.0 0.038 12.7 2.1 1.1 1 0 0 1 1 1 0 Regulator protein PHA-1 RNase_E_G PF10150.4 EGC37246.1 - 0.034 13.3 9.4 0.046 12.9 6.5 1.1 1 0 0 1 1 1 0 Ribonuclease E/G family PRT_C PF08372.5 EGC37246.1 - 0.038 13.4 0.7 0.038 13.4 0.5 1.7 2 0 0 2 2 2 0 Plant phosphoribosyltransferase C-terminal SHS2_FTSA PF02491.15 EGC37246.1 - 0.12 12.3 0.6 12 5.8 0.0 2.5 2 0 0 2 2 2 0 SHS2 domain inserted in FTSA Cytochrom_B562 PF07361.6 EGC37246.1 - 0.15 12.5 19.0 0.74 10.2 1.6 3.0 1 1 0 2 2 2 0 Cytochrome b562 Peptidase_S46 PF10459.4 EGC37246.1 - 0.18 10.1 15.1 0.22 9.9 10.5 1.0 1 0 0 1 1 1 0 Peptidase S46 DASH_Dam1 PF08653.5 EGC37246.1 - 0.21 11.3 3.2 2.6 7.8 0.0 3.1 3 0 0 3 3 3 0 DASH complex subunit Dam1 FAM219A PF15260.1 EGC37246.1 - 0.42 10.9 7.3 0.23 11.8 3.6 1.7 1 1 0 1 1 1 0 Protein family FAM219A Lebercilin PF15619.1 EGC37246.1 - 0.5 9.7 20.1 0.88 8.9 13.9 1.3 1 0 0 1 1 1 0 Ciliary protein causing Leber congenital amaurosis disease DUF3573 PF12097.3 EGC37246.1 - 0.53 8.8 6.1 0.65 8.5 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF3086 PF11285.3 EGC37246.1 - 0.6 8.8 10.3 0.79 8.4 7.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) DUF4047 PF13256.1 EGC37246.1 - 0.72 9.8 9.1 2.7 7.9 3.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4047) Prefoldin_2 PF01920.15 EGC37246.1 - 2.6 7.8 24.7 0.48 10.2 5.0 3.4 2 2 1 3 3 3 0 Prefoldin subunit Allexi_40kDa PF05549.6 EGC37246.1 - 5.3 6.2 12.0 1.6 7.9 2.2 2.0 1 1 1 2 2 2 0 Allexivirus 40kDa protein DUF3138 PF11336.3 EGC37246.1 - 6 4.9 7.7 12 3.9 5.3 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3138) DUF1664 PF07889.7 EGC37246.1 - 7 6.4 13.5 0.45 10.3 2.7 2.6 1 1 2 3 3 3 0 Protein of unknown function (DUF1664) zf-C3HC4_3 PF13920.1 EGC37247.1 - 9.3 6.0 14.6 0.29 10.8 3.3 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PP2C PF00481.16 EGC37248.1 - 5.5e-34 117.7 0.0 7e-34 117.3 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGC37248.1 - 3.2e-06 26.6 0.0 8.3e-06 25.3 0.0 1.7 1 1 0 1 1 1 1 Protein phosphatase 2C SpoIIE PF07228.7 EGC37248.1 - 0.0025 17.5 0.0 0.0095 15.6 0.0 1.9 2 0 0 2 2 2 1 Stage II sporulation protein E (SpoIIE) Copine PF07002.11 EGC37249.1 - 6.5e-39 132.9 0.2 1.5e-38 131.7 0.1 1.7 1 0 0 1 1 1 1 Copine C2 PF00168.25 EGC37249.1 - 1.8e-19 69.3 0.1 1e-10 41.3 0.0 2.5 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC37249.1 - 6.1e-08 32.7 0.0 1.1e-07 31.9 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC37249.1 - 0.00025 20.8 0.1 0.0005 19.8 0.1 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC37249.1 - 0.076 13.1 0.0 0.12 12.4 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain EMP24_GP25L PF01105.19 EGC37250.1 - 3.7e-50 170.1 1.1 4.9e-50 169.7 0.7 1.2 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD Cpn60_TCP1 PF00118.19 EGC37251.1 - 1.5e-118 396.5 12.4 1.7e-118 396.3 8.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family RhoGAP PF00620.22 EGC37252.1 - 3.3e-34 117.7 0.0 5.1e-34 117.0 0.0 1.3 1 0 0 1 1 1 1 RhoGAP domain WD40 PF00400.27 EGC37252.1 - 8.1e-06 25.5 9.2 0.0079 16.0 0.8 4.4 4 0 0 4 4 4 2 WD domain, G-beta repeat PQQ PF01011.16 EGC37252.1 - 0.014 14.8 0.0 0.045 13.2 0.0 1.9 1 0 0 1 1 1 0 PQQ enzyme repeat PQQ_3 PF13570.1 EGC37252.1 - 0.058 13.6 0.0 7.4 6.9 0.0 2.7 2 0 0 2 2 2 0 PQQ-like domain Reg_prop PF07494.6 EGC37252.1 - 0.08 13.0 4.8 10 6.5 0.0 4.7 6 0 0 6 6 6 0 Two component regulator propeller IFRD PF05004.8 EGC37253.1 - 3.4e-07 29.6 0.7 1.2e-06 27.8 0.2 1.9 1 1 1 2 2 2 2 Interferon-related developmental regulator (IFRD) DUF4367 PF14285.1 EGC37253.1 - 7.4 5.8 15.1 19 4.4 10.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4367) zf-TRAF PF02176.13 EGC37254.1 - 3.4e-18 65.7 34.8 7.7e-13 48.6 4.7 3.9 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.11 EGC37254.1 - 0.00043 19.9 20.4 0.0021 17.7 1.4 4.1 2 1 1 4 4 4 3 Seven in absentia protein family DM PF00751.13 EGC37254.1 - 1.5 8.3 17.7 0.069 12.6 2.5 3.1 2 1 0 2 2 2 0 DM DNA binding domain DENN PF02141.16 EGC37255.1 - 5.4e-53 179.4 2.9 5.4e-53 179.4 2.0 3.9 4 0 0 4 4 4 1 DENN (AEX-3) domain uDENN PF03456.13 EGC37255.1 - 3.6e-12 46.0 0.3 1.3e-11 44.3 0.2 2.1 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGC37255.1 - 2.6e-11 43.4 5.6 7.9e-11 41.8 3.9 1.9 1 0 0 1 1 1 1 dDENN domain FNIP PF05725.7 EGC37256.1 - 5.4e-31 106.2 36.3 2.9e-09 36.7 0.2 8.3 4 1 5 9 9 9 8 FNIP Repeat zf-B_box PF00643.19 EGC37256.1 - 8.6e-08 31.9 4.1 1.8e-07 30.8 2.8 1.6 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC37256.1 - 0.0016 18.0 3.2 0.0041 16.8 2.2 1.6 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) zf-C2HC5 PF06221.8 EGC37256.1 - 0.12 12.1 3.1 0.23 11.2 1.4 2.0 2 0 0 2 2 2 0 Putative zinc finger motif, C2HC5-type Rho_Binding PF08912.6 EGC37256.1 - 0.22 11.8 5.4 0.078 13.2 0.8 2.3 2 0 0 2 2 2 0 Rho Binding Pkinase_Tyr PF07714.12 EGC37258.1 - 1.7e-47 161.6 0.0 3.5e-47 160.6 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase Myotub-related PF06602.9 EGC37258.1 - 3.6e-44 150.9 8.8 3.6e-44 150.9 6.1 3.3 2 1 0 2 2 2 1 Myotubularin-like phosphatase domain Pkinase PF00069.20 EGC37258.1 - 3.2e-42 144.4 0.1 1.4e-41 142.3 0.0 2.1 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EGC37258.1 - 1.5e-29 101.0 112.0 2e-09 36.8 0.7 13.3 9 2 4 14 14 14 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC37258.1 - 9.3e-23 79.7 84.0 3.9e-08 32.9 3.1 9.6 6 2 2 9 9 9 6 Leucine rich repeat LRR_1 PF00560.28 EGC37258.1 - 2.4e-12 45.0 66.4 0.96 9.7 0.3 16.6 15 0 0 15 15 15 8 Leucine Rich Repeat LRR_7 PF13504.1 EGC37258.1 - 4.4e-10 38.0 47.2 4.3 7.9 0.1 15.3 14 0 0 14 14 14 6 Leucine rich repeat APH PF01636.18 EGC37258.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family PAP_central PF04928.12 EGC37259.1 - 6.9e-88 293.7 0.9 1.3e-87 292.7 0.0 1.8 2 0 0 2 2 2 1 Poly(A) polymerase central domain PAP_RNA-bind PF04926.10 EGC37259.1 - 1.1e-39 135.4 0.0 2.3e-39 134.4 0.0 1.5 1 0 0 1 1 1 1 Poly(A) polymerase predicted RNA binding domain NTP_transf_2 PF01909.18 EGC37259.1 - 1.1e-08 35.2 0.0 2.5e-08 34.1 0.0 1.5 1 0 0 1 1 1 1 Nucleotidyltransferase domain DUF2217 PF10265.4 EGC37259.1 - 1.6 7.3 6.1 2.6 6.6 4.3 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2217) DUF3201 PF11447.3 EGC37262.1 - 0.0045 16.3 0.2 0.014 14.7 0.0 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF3201) ORC5_C PF14630.1 EGC37262.1 - 0.026 13.9 0.0 0.027 13.9 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus EF-hand_1 PF00036.27 EGC37264.1 - 4.5e-11 41.2 11.2 3.1e-06 26.0 0.4 4.3 4 1 0 4 4 4 2 EF hand EF-hand_8 PF13833.1 EGC37264.1 - 2.5e-10 39.8 9.6 2.8e-05 23.6 0.4 3.6 2 2 1 3 3 3 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC37264.1 - 3.1e-10 39.0 6.2 0.00054 19.6 0.4 4.0 4 1 1 5 5 5 2 EF-hand domain EF-hand_7 PF13499.1 EGC37264.1 - 3.5e-10 39.8 7.0 5.3e-09 36.0 0.8 2.5 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC37264.1 - 7.8e-10 37.6 5.4 0.00019 20.6 0.2 3.4 3 0 0 3 3 3 2 EF hand EF-hand_4 PF12763.2 EGC37264.1 - 0.066 12.9 2.5 0.27 10.9 0.1 2.8 2 1 2 4 4 4 0 Cytoskeletal-regulatory complex EF hand Peptidase_M10_C PF08548.6 EGC37264.1 - 0.096 12.2 0.4 0.16 11.4 0.3 1.4 1 0 0 1 1 1 0 Peptidase M10 serralysin C terminal EF-hand_2 PF09068.6 EGC37264.1 - 0.11 12.5 0.0 11 6.1 0.0 2.3 2 0 0 2 2 2 0 EF hand EF-hand_9 PF14658.1 EGC37264.1 - 0.11 12.4 0.0 0.32 10.9 0.0 1.8 1 1 0 1 1 1 0 EF-hand domain SPARC_Ca_bdg PF10591.4 EGC37264.1 - 0.11 12.5 0.4 0.86 9.6 0.3 2.3 1 1 0 1 1 1 0 Secreted protein acidic and rich in cysteine Ca binding region Zip PF02535.17 EGC37266.1 - 0.04 12.9 14.7 0.057 12.4 10.2 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter Tmemb_9 PF05434.6 EGC37267.1 - 0.22 11.2 0.1 0.22 11.2 0.1 1.8 2 0 0 2 2 2 0 TMEM9 Adeno_E3_CR2 PF02439.10 EGC37268.1 - 0.003 17.0 1.6 0.0074 15.8 1.1 1.6 1 0 0 1 1 1 1 Adenovirus E3 region protein CR2 EphA2_TM PF14575.1 EGC37268.1 - 0.017 15.4 0.1 0.041 14.2 0.0 1.5 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain FAM163 PF15069.1 EGC37268.1 - 0.029 14.9 0.0 0.065 13.8 0.0 1.5 1 0 0 1 1 1 0 FAM163 family DUF912 PF06024.7 EGC37269.1 - 0.00012 22.0 0.8 0.0004 20.4 0.5 1.8 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) ETRAMP PF09716.5 EGC37269.1 - 0.0046 16.8 0.4 0.0046 16.8 0.3 2.8 3 0 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) TMEM51 PF15345.1 EGC37269.1 - 0.0062 16.2 0.2 0.015 15.0 0.2 1.6 1 0 0 1 1 1 1 Transmembrane protein 51 DUF2407_C PF13373.1 EGC37269.1 - 0.011 15.6 1.3 0.023 14.5 0.9 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Podoplanin PF05808.6 EGC37269.1 - 0.033 13.7 0.0 0.063 12.8 0.0 1.4 1 0 0 1 1 1 0 Podoplanin SKG6 PF08693.5 EGC37269.1 - 0.062 12.6 0.3 0.062 12.6 0.2 2.0 2 0 0 2 2 2 0 Transmembrane alpha-helix domain IP_trans PF02121.13 EGC37270.1 - 1.7e-97 325.5 1.4 2e-97 325.3 0.9 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Ribosomal_L22e PF01776.12 EGC37271.1 - 7.3e-44 148.3 4.4 8.4e-44 148.1 3.0 1.0 1 0 0 1 1 1 1 Ribosomal L22e protein family Dynamin_N PF00350.18 EGC37272.1 - 7.7e-21 74.6 0.0 1e-19 70.9 0.0 2.3 1 1 0 1 1 1 1 Dynamin family EF-hand_4 PF12763.2 EGC37272.1 - 2e-19 69.2 0.1 8.1e-19 67.2 0.0 2.1 2 0 0 2 2 2 1 Cytoskeletal-regulatory complex EF hand MMR_HSR1 PF01926.18 EGC37272.1 - 2.1e-09 37.3 0.0 6.3e-09 35.7 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase Miro PF08477.8 EGC37272.1 - 8.4e-05 23.0 0.0 0.0078 16.7 0.0 2.5 2 0 0 2 2 2 1 Miro-like protein GTP_EFTU PF00009.22 EGC37272.1 - 0.00026 20.5 0.0 0.00065 19.1 0.0 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC37272.1 - 0.009 15.5 0.0 0.86 9.0 0.0 2.6 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation FeoB_N PF02421.13 EGC37272.1 - 0.012 14.8 0.0 1.7 7.8 0.0 2.3 2 0 0 2 2 2 0 Ferrous iron transport protein B EF-hand_1 PF00036.27 EGC37272.1 - 0.014 14.6 0.1 0.064 12.5 0.0 2.3 2 0 0 2 2 2 0 EF hand AAA_28 PF13521.1 EGC37272.1 - 0.027 14.4 0.0 0.052 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGC37272.1 - 0.07 13.2 0.0 0.26 11.4 0.0 2.1 1 1 0 1 1 1 0 AAA domain EF-hand_7 PF13499.1 EGC37272.1 - 0.095 12.8 0.0 0.44 10.7 0.0 2.3 2 1 0 2 2 2 0 EF-hand domain pair DUF599 PF04654.7 EGC37274.1 - 8.8e-54 181.9 10.8 1.1e-53 181.6 7.5 1.0 1 0 0 1 1 1 1 Protein of unknown function, DUF599 Pox_I5 PF04713.7 EGC37274.1 - 0.17 11.6 0.2 0.17 11.6 0.1 2.6 2 0 0 2 2 2 0 Poxvirus protein I5 Cpn60_TCP1 PF00118.19 EGC37275.1 - 5.6e-81 272.5 20.6 2.8e-71 240.6 11.6 2.8 2 1 0 2 2 2 2 TCP-1/cpn60 chaperonin family YcgR PF07317.7 EGC37275.1 - 0.00041 20.0 1.5 0.62 9.8 0.3 2.5 2 0 0 2 2 2 2 Flagellar regulator YcgR NMO PF03060.10 EGC37276.1 - 6e-58 196.5 0.0 6.8e-58 196.3 0.0 1.0 1 0 0 1 1 1 1 Nitronate monooxygenase IMPDH PF00478.20 EGC37276.1 - 1.1e-07 31.1 0.0 7.3e-05 21.8 0.0 2.1 2 0 0 2 2 2 2 IMP dehydrogenase / GMP reductase domain His_biosynth PF00977.16 EGC37276.1 - 2.3e-05 23.7 0.1 0.00023 20.4 0.0 2.1 2 0 0 2 2 2 1 Histidine biosynthesis protein DUF561 PF04481.7 EGC37276.1 - 0.063 12.2 0.2 0.13 11.2 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF561) IGPS PF00218.16 EGC37276.1 - 0.12 11.4 0.0 13 4.7 0.0 2.5 2 1 0 2 2 2 0 Indole-3-glycerol phosphate synthase Pkinase PF00069.20 EGC37277.1 - 1e-29 103.5 3.0 1.1e-29 103.3 2.1 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37277.1 - 5.3e-23 81.4 0.5 5.5e-23 81.3 0.3 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase NCD1 PF04904.8 EGC37277.1 - 0.0029 17.3 0.0 0.0059 16.3 0.0 1.7 1 0 0 1 1 1 1 NAB conserved region 1 (NCD1) Ank_2 PF12796.2 EGC37278.1 - 2.7e-46 155.8 0.0 4.5e-20 71.7 0.0 3.3 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC37278.1 - 6.8e-38 126.6 0.0 5e-09 35.5 0.0 5.6 5 0 0 5 5 5 5 Ankyrin repeat zf-DHHC PF01529.15 EGC37278.1 - 5.8e-32 110.4 5.8 5.8e-32 110.4 4.0 3.0 3 1 0 3 3 3 1 DHHC palmitoyltransferase Ank_5 PF13857.1 EGC37278.1 - 7.8e-32 108.5 1.1 4e-09 36.4 0.0 5.2 1 1 4 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC37278.1 - 2.6e-31 104.5 0.3 2.2e-08 33.5 0.0 6.3 6 0 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EGC37278.1 - 2.3e-29 101.2 3.1 2e-12 47.2 0.0 4.7 3 1 1 4 4 4 3 Ankyrin repeats (many copies) PBP1_TM PF14812.1 EGC37278.1 - 0.074 13.3 7.8 0.15 12.4 5.4 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal CDC45 PF02724.9 EGC37278.1 - 0.74 7.7 6.5 1 7.3 4.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DRTGG PF07085.7 EGC37280.1 - 0.12 11.9 0.0 0.19 11.3 0.0 1.3 1 0 0 1 1 1 0 DRTGG domain DUF900 PF05990.7 EGC37281.1 - 9.5e-25 87.2 0.1 1.4e-24 86.7 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EGC37281.1 - 0.0013 18.4 0.0 0.0021 17.8 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC37281.1 - 0.008 16.0 0.0 0.012 15.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2968 PF11180.3 EGC37282.1 - 0.02 14.2 2.9 0.024 14.0 2.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2968) DUF4509 PF14970.1 EGC37282.1 - 0.88 9.2 4.8 0.99 9.0 3.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4509) DUF1090 PF06476.7 EGC37282.1 - 1.7 8.3 11.7 2.2 7.9 8.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1090) DUF4602 PF15375.1 EGC37282.1 - 2 8.4 9.0 0.61 10.1 0.9 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4602) TMPIT PF07851.8 EGC37282.1 - 2.1 7.3 11.0 2.3 7.1 7.6 1.0 1 0 0 1 1 1 0 TMPIT-like protein eIF-4B PF06273.6 EGC37282.1 - 5.8 5.5 6.0 6.3 5.4 4.2 1.1 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B zf-RING_2 PF13639.1 EGC37283.1 - 1.5e-09 37.5 8.7 3e-09 36.5 6.0 1.5 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC37283.1 - 2e-07 31.0 5.0 1.9e-06 27.8 3.4 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC37283.1 - 2.8e-07 30.0 7.0 4.6e-07 29.4 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37283.1 - 3.4e-07 29.7 10.6 7.3e-07 28.7 7.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37283.1 - 2.7e-06 27.3 10.4 6e-06 26.1 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37283.1 - 0.00015 21.4 8.5 0.00027 20.5 5.9 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC37283.1 - 0.008 15.7 7.4 0.014 14.9 5.2 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_IE-1 PF05290.6 EGC37283.1 - 0.027 14.2 2.4 0.049 13.3 1.7 1.4 1 0 0 1 1 1 0 Baculovirus immediate-early protein (IE-0) zf-Apc11 PF12861.2 EGC37283.1 - 0.033 14.0 1.1 0.14 11.9 0.7 2.1 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF3889 PF13028.1 EGC37283.1 - 0.078 12.6 2.0 0.16 11.6 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3889) zf-C3HC4_4 PF15227.1 EGC37283.1 - 0.16 11.8 11.4 0.12 12.2 6.5 2.0 2 0 0 2 2 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EGC37283.1 - 0.31 10.9 6.5 0.69 9.8 4.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 EGC37283.1 - 2.9 7.6 7.0 1.4 8.6 2.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger zf-RING_2 PF13639.1 EGC37284.1 - 9.2e-10 38.2 8.9 1.4e-09 37.6 6.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC37284.1 - 9.1e-08 31.6 7.0 1.4e-07 31.0 4.9 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37284.1 - 4.6e-07 29.3 10.4 8.2e-07 28.5 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37284.1 - 1.2e-06 28.4 4.2 2.6e-06 27.4 2.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC37284.1 - 2.8e-06 27.2 10.2 4.6e-06 26.5 7.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37284.1 - 3.6e-05 23.3 8.9 6.3e-05 22.6 6.2 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC37284.1 - 0.0011 18.5 9.4 0.0018 17.7 6.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC37284.1 - 0.0029 17.3 1.1 0.0072 16.1 0.7 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger THRAP3_BCLAF1 PF15440.1 EGC37284.1 - 0.0035 16.0 42.8 0.0059 15.3 29.6 1.3 1 1 0 1 1 1 1 THRAP3/BCLAF1 family zf-RING_6 PF14835.1 EGC37284.1 - 0.065 13.0 3.7 0.14 11.9 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-C3HC4_4 PF15227.1 EGC37284.1 - 0.07 13.0 9.9 0.18 11.6 6.8 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EGC37284.1 - 0.32 10.8 5.5 0.77 9.6 3.8 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EGC37284.1 - 0.42 10.2 4.1 0.85 9.2 2.8 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DZR PF12773.2 EGC37284.1 - 0.98 9.2 4.8 3 7.7 3.3 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_UBOX PF13445.1 EGC37284.1 - 1.1 8.9 4.7 3.6 7.3 3.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger C1_4 PF07975.7 EGC37284.1 - 2.2 8.3 6.6 6 6.9 4.4 1.8 1 1 0 1 1 1 0 TFIIH C1-like domain GAGA_bind PF06217.7 EGC37284.1 - 2.9 7.7 13.7 4.5 7.1 9.5 1.4 1 0 0 1 1 1 0 GAGA binding protein-like family Ras PF00071.17 EGC37288.1 - 2e-20 72.7 0.4 7.3e-18 64.4 0.1 2.8 2 1 0 2 2 2 2 Ras family Miro PF08477.8 EGC37288.1 - 2.2e-13 50.7 2.9 1.3e-12 48.2 0.0 3.1 3 1 0 3 3 3 1 Miro-like protein Arf PF00025.16 EGC37288.1 - 1.2e-08 34.4 2.2 3.3e-07 29.6 0.4 2.5 2 0 0 2 2 2 2 ADP-ribosylation factor family Secretin_N_2 PF07655.8 EGC37288.1 - 0.028 14.8 3.6 0.028 14.8 2.5 6.0 3 2 0 3 3 3 0 Secretin N-terminal domain 4HBT PF03061.17 EGC37289.1 - 4.8e-10 39.4 0.0 0.00041 20.4 0.0 2.3 2 0 0 2 2 2 2 Thioesterase superfamily RRM_1 PF00076.17 EGC37289.1 - 8.8e-07 28.4 0.2 2.8e-06 26.8 0.1 2.0 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37289.1 - 0.00026 20.9 0.1 0.00062 19.6 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Mcm10 PF09332.6 EGC37290.1 - 1.9 7.7 10.1 2.7 7.2 7.0 1.2 1 0 0 1 1 1 0 Mcm10 replication factor TIG PF01833.19 EGC37291.1 - 6.4e-14 51.7 52.4 9.1e-06 25.5 1.5 7.9 7 1 1 8 8 8 6 IPT/TIG domain HPD PF05044.7 EGC37291.1 - 0.0044 16.6 0.0 2.3 7.8 0.0 2.6 2 0 0 2 2 2 2 Homeo-prospero domain EGF_2 PF07974.8 EGC37291.1 - 0.14 12.3 11.6 0.31 11.2 8.1 1.6 1 0 0 1 1 1 0 EGF-like domain Glycos_transf_2 PF00535.21 EGC37292.1 - 4.6e-39 133.7 0.0 5.7e-39 133.4 0.0 1.1 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGC37292.1 - 2.3e-13 50.4 0.0 3.3e-13 49.9 0.0 1.1 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_tranf_2_2 PF10111.4 EGC37292.1 - 5.3e-09 35.5 0.0 7.8e-09 35.0 0.0 1.2 1 0 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_21 PF13506.1 EGC37292.1 - 9.3e-06 25.0 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase family 21 Glyco_tranf_2_4 PF13704.1 EGC37292.1 - 0.0068 16.6 0.0 0.012 15.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferase family 2 Glyco_tranf_2_5 PF13712.1 EGC37292.1 - 0.032 13.4 0.0 0.047 12.9 0.0 1.3 1 0 0 1 1 1 0 Glycosyltransferase like family Glyco_trans_2_3 PF13632.1 EGC37292.1 - 0.07 12.8 0.0 0.099 12.3 0.0 1.2 1 0 0 1 1 1 0 Glycosyl transferase family group 2 Glyco_transf_7N PF13733.1 EGC37292.1 - 0.09 12.1 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 N-terminal region of glycosyl transferase group 7 DUF4549 PF15082.1 EGC37292.1 - 0.12 11.9 0.0 0.21 11.2 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4549) Glyco_hydro_20 PF00728.17 EGC37294.1 - 2.6e-87 293.2 1.8 3.3e-87 292.9 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGC37294.1 - 1.3e-17 64.6 0.2 2.5e-17 63.7 0.1 1.5 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGC37294.1 - 3.8e-08 33.9 0.0 6.2e-08 33.2 0.0 1.3 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 Mito_fiss_reg PF05308.6 EGC37295.1 - 0.047 13.0 3.7 0.055 12.8 2.6 1.1 1 0 0 1 1 1 0 Mitochondrial fission regulator Gag_spuma PF03276.9 EGC37295.1 - 0.12 10.6 0.2 0.11 10.7 0.1 1.1 1 0 0 1 1 1 0 Spumavirus gag protein WWE PF02825.15 EGC37298.1 - 0.00037 19.8 1.9 0.00037 19.8 1.3 2.5 2 1 0 2 2 2 1 WWE domain PRESAN PF09687.5 EGC37298.1 - 0.0079 16.2 1.3 0.0079 16.2 0.9 2.9 3 0 0 3 3 3 1 Plasmodium RESA N-terminal Pex14_N PF04695.8 EGC37298.1 - 1.4 8.9 16.6 1.9 8.5 6.1 2.7 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region IBR PF01485.16 EGC37299.1 - 2.6e-15 56.0 25.0 4.8e-13 48.7 2.9 3.7 3 1 0 3 3 3 2 IBR domain zf-C3HC4_2 PF13923.1 EGC37299.1 - 2.6e-05 24.1 10.2 2.6e-05 24.1 7.1 4.2 3 1 0 3 3 3 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC37299.1 - 8.3e-05 22.1 4.3 8.3e-05 22.1 3.0 3.9 2 2 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) UBA_4 PF14555.1 EGC37299.1 - 0.00068 19.1 0.0 0.71 9.4 0.0 2.7 2 0 0 2 2 2 2 UBA-like domain zf-C3HC4 PF00097.20 EGC37299.1 - 0.0034 16.9 3.0 0.0034 16.9 2.1 4.2 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DUF4284 PF14112.1 EGC37299.1 - 0.023 15.1 8.9 0.14 12.6 1.3 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF4284) Cyt-b5 PF00173.23 EGC37300.1 - 1.3e-17 63.3 0.2 2.4e-17 62.4 0.1 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain Skp1_POZ PF03931.10 EGC37300.1 - 0.049 13.7 0.6 0.13 12.3 0.4 1.9 1 1 0 1 1 1 0 Skp1 family, tetramerisation domain UBN2 PF14223.1 EGC37300.1 - 0.66 9.7 3.5 1.2 8.8 0.8 2.4 1 1 2 3 3 3 0 gag-polypeptide of LTR copia-type UQ_con PF00179.21 EGC37301.1 - 1.6e-25 89.1 0.2 3.4e-25 88.1 0.1 1.5 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Mucin PF01456.12 EGC37301.1 - 2e-05 24.3 12.4 2.5e-05 24.0 8.6 1.2 1 0 0 1 1 1 1 Mucin-like glycoprotein RWD PF05773.17 EGC37301.1 - 0.0086 15.9 0.0 0.0086 15.9 0.0 2.4 2 1 0 2 2 2 1 RWD domain 7TM_GPCR_Srd PF10317.4 EGC37301.1 - 0.033 13.1 2.3 0.049 12.6 1.6 1.2 1 0 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Srd DUF3439 PF11921.3 EGC37301.1 - 1.1 9.0 8.1 1.9 8.2 5.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ABC2_membrane_3 PF12698.2 EGC37301.1 - 1.5 7.7 13.4 2.4 7.1 9.3 1.3 1 0 0 1 1 1 0 ABC-2 family transporter protein Pex14_N PF04695.8 EGC37301.1 - 2.4 8.2 11.4 6.9 6.7 7.9 1.9 1 1 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region TMEM154 PF15102.1 EGC37301.1 - 9.7 5.8 14.6 9.8 5.8 9.1 1.8 1 1 0 1 1 1 0 TMEM154 protein family Kelch_4 PF13418.1 EGC37302.1 - 4.8e-07 29.4 11.0 0.0046 16.7 0.0 5.2 3 1 2 5 5 5 3 Galactose oxidase, central domain zf-B_box PF00643.19 EGC37302.1 - 2.6e-06 27.2 10.6 5e-06 26.3 7.4 1.5 1 0 0 1 1 1 1 B-box zinc finger Kelch_6 PF13964.1 EGC37302.1 - 7e-05 22.8 15.1 0.18 12.0 0.2 6.0 4 1 2 6 6 6 2 Kelch motif Kelch_1 PF01344.20 EGC37302.1 - 0.00038 19.9 12.4 0.13 11.7 0.1 5.3 5 0 0 5 5 5 3 Kelch motif Kelch_5 PF13854.1 EGC37302.1 - 0.0024 17.8 7.2 0.57 10.2 0.1 4.5 5 0 0 5 5 5 2 Kelch motif Kelch_3 PF13415.1 EGC37302.1 - 0.55 10.4 14.8 6 7.1 0.0 5.5 6 0 0 6 6 6 0 Galactose oxidase, central domain Histone PF00125.19 EGC37303.1 - 1.6e-18 66.5 0.1 2.1e-18 66.2 0.1 1.2 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CBFD_NFYB_HMF PF00808.18 EGC37303.1 - 1.1e-06 28.6 0.2 1.5e-06 28.1 0.2 1.3 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone TFIID_20kDa PF03847.8 EGC37303.1 - 0.00091 19.4 0.0 0.0018 18.5 0.0 1.5 1 1 0 1 1 1 1 Transcription initiation factor TFIID subunit A DUF3987 PF13148.1 EGC37303.1 - 0.0046 15.5 0.0 0.0046 15.5 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3987) CENP-S PF15630.1 EGC37303.1 - 0.026 14.6 0.1 0.037 14.1 0.1 1.2 1 0 0 1 1 1 0 Kinetochore component CENP-S Methyltrn_RNA_3 PF02598.12 EGC37304.1 - 6.2e-51 173.4 3.7 6.2e-51 173.4 2.5 1.8 2 1 0 2 2 2 1 Putative RNA methyltransferase DUF496 PF04363.7 EGC37304.1 - 0.49 10.2 18.4 0.11 12.3 3.2 3.9 3 1 1 4 4 4 0 Protein of unknown function (DUF496) PIG-H PF10181.4 EGC37305.1 - 7.2e-19 67.2 0.4 2.3e-18 65.5 0.3 1.9 1 0 0 1 1 1 1 GPI-GlcNAc transferase complex, PIG-H component eIF-5_eIF-2B PF01873.12 EGC37307.1 - 8.9e-36 122.3 0.2 1.9e-35 121.2 0.1 1.6 1 0 0 1 1 1 1 Domain found in IF2B/IF5 W2 PF02020.13 EGC37307.1 - 8.5e-22 76.9 0.5 8.5e-22 76.9 0.4 2.4 2 0 0 2 2 2 1 eIF4-gamma/eIF5/eIF2-epsilon Abhydrolase_3 PF07859.8 EGC37308.1 - 5.1e-45 153.6 0.0 6.4e-45 153.3 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGC37308.1 - 8.1e-14 51.0 0.1 1.3e-13 50.3 0.1 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGC37308.1 - 6.4e-06 25.5 0.0 0.004 16.3 0.0 2.1 2 0 0 2 2 2 2 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC37308.1 - 1.5e-05 24.7 0.0 2.2e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC37308.1 - 0.00037 20.4 0.0 0.00074 19.4 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family DLH PF01738.13 EGC37308.1 - 0.0068 15.7 0.0 0.013 14.8 0.0 1.4 1 0 0 1 1 1 1 Dienelactone hydrolase family Abhydrolase_3 PF07859.8 EGC37309.1 - 1.1e-57 195.0 0.0 1.4e-57 194.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGC37309.1 - 1.2e-08 34.0 0.1 1.8e-08 33.4 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGC37309.1 - 4.1e-05 22.9 0.0 0.00013 21.2 0.0 1.7 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC37309.1 - 0.00046 19.9 0.0 0.00058 19.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGC37309.1 - 0.001 17.8 0.0 0.0053 15.5 0.0 1.9 2 0 0 2 2 2 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC37310.1 - 3e-63 213.1 0.0 3.9e-63 212.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGC37310.1 - 1.8e-08 33.4 0.1 2.7e-08 32.8 0.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) COesterase PF00135.23 EGC37310.1 - 1.1e-06 27.6 0.0 0.0067 15.1 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Peptidase_S9 PF00326.16 EGC37310.1 - 3.6e-05 23.0 0.1 0.00021 20.5 0.1 1.9 1 1 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC37310.1 - 9.4e-05 22.1 0.0 0.00014 21.6 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase_phd PF10503.4 EGC37310.1 - 0.0028 16.9 0.0 0.03 13.5 0.0 2.5 2 1 0 2 2 2 1 Esterase PHB depolymerase Lipase_3 PF01764.20 EGC37310.1 - 0.14 11.7 0.0 0.24 11.0 0.0 1.3 1 0 0 1 1 1 0 Lipase (class 3) Abhydrolase_3 PF07859.8 EGC37311.1 - 7.2e-64 215.2 0.0 9.2e-64 214.8 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC37311.1 - 1.5e-06 27.5 0.1 3.5e-06 26.4 0.1 1.5 1 1 0 1 1 1 1 Prolyl oligopeptidase family DUF2424 PF10340.4 EGC37311.1 - 5e-06 25.3 0.0 6.6e-06 25.0 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGC37311.1 - 8.3e-06 25.6 0.0 1.3e-05 24.9 0.0 1.4 1 1 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGC37311.1 - 8.9e-06 24.6 0.0 0.022 13.4 0.0 2.1 2 0 0 2 2 2 2 Carboxylesterase family Esterase_phd PF10503.4 EGC37311.1 - 0.0025 17.0 0.1 0.24 10.6 0.0 2.8 2 1 0 2 2 2 1 Esterase PHB depolymerase DUF2974 PF11187.3 EGC37311.1 - 0.067 12.5 0.0 0.11 11.8 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2974) Abhydrolase_2 PF02230.11 EGC37311.1 - 0.079 12.3 0.0 0.34 10.3 0.0 1.9 1 1 1 2 2 2 0 Phospholipase/Carboxylesterase tRNA-synt_2 PF00152.15 EGC37312.1 - 6.7e-91 304.5 0.0 1.2e-90 303.7 0.0 1.4 1 0 0 1 1 1 1 tRNA synthetases class II (D, K and N) tRNA-synt_2d PF01409.15 EGC37312.1 - 1e-07 31.4 0.0 0.00098 18.3 0.0 2.8 3 0 0 3 3 3 2 tRNA synthetases class II core domain (F) tRNA_anti-codon PF01336.20 EGC37312.1 - 1.6e-07 31.0 0.1 6.8e-06 25.8 0.1 2.8 2 1 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2b PF00587.20 EGC37312.1 - 0.0024 17.4 1.1 0.13 11.7 0.0 3.1 4 0 0 4 4 4 1 tRNA synthetase class II core domain (G, H, P, S and T) Peroxidase_2 PF01328.12 EGC37313.1 - 0.039 12.6 0.2 0.072 11.7 0.1 1.3 1 0 0 1 1 1 0 Peroxidase, family 2 FAM163 PF15069.1 EGC37314.1 - 0.092 13.3 6.3 0.47 11.0 4.4 2.0 1 1 0 1 1 1 0 FAM163 family ATP-synt_8 PF00895.15 EGC37314.1 - 3.7 7.8 5.6 0.72 10.1 0.6 2.4 2 1 0 2 2 2 0 ATP synthase protein 8 RhoGEF PF00621.15 EGC37315.1 - 4.3e-32 111.4 10.8 4.3e-32 111.4 7.5 2.4 3 0 0 3 3 3 1 RhoGEF domain Ribosomal_L14 PF00238.14 EGC37316.1 - 1.5e-29 102.2 0.0 1.7e-29 102.0 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L14p/L23e Cyt-b5 PF00173.23 EGC37317.1 - 2.3e-21 75.3 0.0 3.9e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain zf-CDGSH PF09360.5 EGC37317.1 - 1.2e-06 28.2 0.2 3.6e-06 26.6 0.1 1.9 1 0 0 1 1 1 1 Iron-binding zinc finger CDGSH type SNF2_N PF00176.18 EGC37318.1 - 1.1e-70 237.8 1.0 1.1e-70 237.8 0.7 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Chromo PF00385.19 EGC37318.1 - 4.4e-19 67.9 17.3 4.5e-10 39.0 0.2 4.2 4 0 0 4 4 4 2 Chromo (CHRromatin Organisation MOdifier) domain Helicase_C PF00271.26 EGC37318.1 - 3e-15 55.8 0.3 1.2e-14 53.8 0.0 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Myb_DNA-binding PF00249.26 EGC37318.1 - 0.0002 21.3 4.3 0.27 11.3 0.5 3.0 2 0 0 2 2 2 2 Myb-like DNA-binding domain GCV_H PF01597.14 EGC37320.1 - 5.6e-13 48.6 0.6 6.3e-13 48.4 0.4 1.0 1 0 0 1 1 1 1 Glycine cleavage H-protein OEP PF02321.13 EGC37322.1 - 0.12 11.9 5.8 0.28 10.7 4.0 1.6 1 0 0 1 1 1 0 Outer membrane efflux protein DUF2968 PF11180.3 EGC37322.1 - 0.37 10.1 7.4 0.42 9.9 4.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2968) DEC-1_N PF04625.8 EGC37322.1 - 8.4 4.9 8.0 1.4 7.5 3.2 1.4 2 0 0 2 2 2 0 DEC-1 protein, N-terminal region Transferase PF02458.10 EGC37323.1 - 2.1e-14 52.8 0.0 2.9e-14 52.3 0.0 1.1 1 0 0 1 1 1 1 Transferase family Condensation PF00668.15 EGC37323.1 - 0.00066 18.6 0.0 0.0014 17.5 0.0 1.4 1 1 0 1 1 1 1 Condensation domain DUF3920 PF13058.1 EGC37323.1 - 0.0081 15.9 0.9 0.0081 15.9 0.6 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3920) tRNA-synt_1d PF00750.14 EGC37324.1 - 1.2e-64 218.3 0.0 8.5e-63 212.2 0.0 2.6 2 1 0 2 2 2 1 tRNA synthetases class I (R) DALR_1 PF05746.10 EGC37324.1 - 3.2e-24 85.1 0.0 5.6e-23 81.1 0.0 2.6 2 0 0 2 2 2 1 DALR anticodon binding domain Arg_tRNA_synt_N PF03485.11 EGC37324.1 - 0.0016 18.9 0.9 0.0088 16.5 0.5 2.3 2 0 0 2 2 2 1 Arginyl tRNA synthetase N terminal domain FragX_IP PF05994.6 EGC37325.1 - 2.4e-288 958.4 14.9 2.4e-288 958.4 10.3 1.8 2 0 0 2 2 2 1 Cytoplasmic Fragile-X interacting family DUF1394 PF07159.7 EGC37325.1 - 2.6e-11 43.2 2.6 4.6e-10 39.0 1.8 2.4 1 1 0 1 1 1 1 Protein of unknown function (DUF1394) AGT PF11440.3 EGC37326.1 - 0.033 13.0 0.2 0.033 13.0 0.1 1.0 1 0 0 1 1 1 0 DNA alpha-glucosyltransferase Apis_Csd PF11671.3 EGC37326.1 - 3.7 7.3 15.0 4 7.2 10.4 1.1 1 0 0 1 1 1 0 Complementary sex determiner protein GMC_oxred_N PF00732.14 EGC37327.1 - 4.7e-39 134.3 0.0 6.2e-39 133.9 0.0 1.2 1 0 0 1 1 1 1 GMC oxidoreductase GMC_oxred_C PF05199.8 EGC37327.1 - 3.6e-24 85.6 0.0 5.5e-24 85.1 0.0 1.3 1 0 0 1 1 1 1 GMC oxidoreductase Nucleoporin_C PF03177.9 EGC37329.1 - 1.3e-17 63.6 25.9 1.2e-16 60.4 10.4 2.5 2 0 0 2 2 2 2 Non-repetitive/WGA-negative nucleoporin C-terminal DUF1770 PF08589.5 EGC37329.1 - 0.056 14.0 0.0 0.18 12.4 0.0 1.9 1 0 0 1 1 1 0 Fungal protein of unknown function (DUF1770) DUF4504 PF14953.1 EGC37330.1 - 4.2e-19 68.8 10.3 5.5e-18 65.2 7.1 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4504) PhdYeFM_antitox PF02604.14 EGC37330.1 - 0.066 12.8 0.0 0.16 11.5 0.0 1.6 1 0 0 1 1 1 0 Antitoxin Phd_YefM, type II toxin-antitoxin system NIF PF03031.13 EGC37331.1 - 1.3e-21 76.9 4.7 1.7e-21 76.5 2.0 2.2 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase BRCT PF00533.21 EGC37331.1 - 3.4e-11 43.1 0.2 1.2e-10 41.3 0.2 2.0 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC37331.1 - 8.4e-08 31.9 0.0 1.7e-07 31.0 0.0 1.5 1 0 0 1 1 1 1 twin BRCT domain HAD_2 PF13419.1 EGC37331.1 - 0.12 12.6 0.0 0.5 10.5 0.0 1.9 2 1 0 2 2 2 0 Haloacid dehalogenase-like hydrolase DUF2838 PF10998.3 EGC37332.1 - 2e-34 117.8 8.9 2e-34 117.8 6.2 2.5 3 0 0 3 3 3 1 Protein of unknown function (DUF2838) WD40 PF00400.27 EGC37333.1 - 7.7e-47 155.5 25.0 2.9e-11 42.7 0.3 6.9 6 1 0 6 6 6 6 WD domain, G-beta repeat PhyH PF05721.8 EGC37333.1 - 2.4e-09 37.5 3.1 7.5e-09 35.9 0.1 3.0 3 1 0 3 3 3 1 Phytanoyl-CoA dioxygenase (PhyH) PD40 PF07676.7 EGC37333.1 - 0.093 12.4 1.3 7.6 6.3 0.1 3.7 4 0 0 4 4 4 0 WD40-like Beta Propeller Repeat HCaRG PF07258.9 EGC37334.1 - 2.1e-26 92.5 6.9 2.4e-26 92.3 4.8 1.0 1 0 0 1 1 1 1 HCaRG protein UPF0489 PF12640.2 EGC37334.1 - 0.15 12.2 0.9 0.34 11.0 0.6 1.6 1 1 0 1 1 1 0 UPF0489 domain Beta-lactamase PF00144.19 EGC37335.1 - 2.8e-35 121.9 0.0 5.8e-21 74.8 0.0 2.0 2 0 0 2 2 2 2 Beta-lactamase POX PF07526.6 EGC37337.1 - 0.12 12.5 0.7 0.12 12.6 0.5 1.1 1 0 0 1 1 1 0 Associated with HOX DUF912 PF06024.7 EGC37337.1 - 0.25 11.4 6.5 0.32 11.0 4.5 1.3 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Menin PF05053.8 EGC37337.1 - 1.2 7.1 7.0 1.3 7.1 4.8 1.0 1 0 0 1 1 1 0 Menin Secretin_N_2 PF07655.8 EGC37337.1 - 3 8.3 15.8 4.2 7.8 10.9 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain WD40 PF00400.27 EGC37338.1 - 2.3e-84 274.5 27.5 1.8e-13 49.7 0.4 7.2 7 0 0 7 7 7 7 WD domain, G-beta repeat Nup160 PF11715.3 EGC37338.1 - 1.2e-09 36.8 8.8 0.045 11.8 0.3 5.0 2 2 2 4 4 4 4 Nucleoporin Nup120/160 LisH PF08513.6 EGC37338.1 - 6e-07 29.0 0.7 1.2e-06 28.0 0.5 1.5 1 0 0 1 1 1 1 LisH Hira PF07569.6 EGC37338.1 - 0.29 10.3 2.4 0.88 8.7 0.0 2.8 4 0 0 4 4 4 0 TUP1-like enhancer of split DUF342 PF03961.8 EGC37338.1 - 0.39 9.0 1.3 0.58 8.5 0.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) RhoGEF PF00621.15 EGC37339.1 - 6.6e-37 127.1 8.5 6.6e-37 127.1 5.9 2.0 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EGC37339.1 - 0.00042 20.4 1.4 0.00042 20.4 1.0 2.9 2 0 0 2 2 2 1 PH domain DUF2465 PF10239.4 EGC37340.1 - 3.7e-37 128.2 2.5 6.3e-37 127.4 1.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2465) KIP1 PF07765.7 EGC37340.1 - 0.037 13.8 0.3 0.33 10.8 0.1 2.5 2 0 0 2 2 2 0 KIP1-like protein CDV3 PF15359.1 EGC37340.1 - 0.56 10.2 4.4 1 9.4 3.1 1.4 1 0 0 1 1 1 0 Carnitine deficiency-associated protein 3 FNIP PF05725.7 EGC37341.1 - 8.8e-12 44.7 21.0 3.3e-08 33.3 0.7 5.9 3 2 1 5 5 5 4 FNIP Repeat LRR_4 PF12799.2 EGC37341.1 - 0.0053 16.3 9.5 0.78 9.4 0.6 4.0 2 1 1 3 3 3 3 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC37341.1 - 0.19 11.8 5.6 3.1 8.1 0.1 4.2 3 2 0 3 3 3 0 Leucine Rich Repeat LRR_7 PF13504.1 EGC37341.1 - 0.25 11.6 6.6 38 5.1 0.1 4.9 5 2 0 5 5 5 0 Leucine rich repeat LRR_6 PF13516.1 EGC37341.1 - 0.41 10.8 6.0 30 5.1 0.1 4.4 4 2 0 4 4 4 0 Leucine Rich repeat DUF605 PF04652.11 EGC37342.1 - 0.6 9.4 8.7 0.58 9.5 6.0 1.1 1 0 0 1 1 1 0 Vta1 like GFA PF04828.9 EGC37343.1 - 4.3e-09 36.1 0.1 4.3e-09 36.1 0.0 1.7 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme ABC_membrane PF00664.18 EGC37344.1 - 4.8e-52 177.0 19.3 4.8e-52 177.0 13.3 1.7 2 0 0 2 2 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGC37344.1 - 2.1e-33 115.5 0.1 7.6e-33 113.7 0.0 2.1 1 0 0 1 1 1 1 ABC transporter Peptidase_S8 PF00082.17 EGC37344.1 - 9e-32 110.3 4.1 1.5e-31 109.5 2.8 1.4 1 0 0 1 1 1 1 Subtilase family MitMem_reg PF13012.1 EGC37344.1 - 2.9e-24 85.3 0.1 2.9e-24 85.3 0.1 2.2 2 0 0 2 2 2 1 Maintenance of mitochondrial structure and function JAB PF01398.16 EGC37344.1 - 8.1e-21 73.8 0.1 3.6e-20 71.8 0.0 2.2 2 0 0 2 2 2 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease SMC_N PF02463.14 EGC37344.1 - 1.3e-05 24.5 0.2 0.0018 17.5 0.0 2.5 1 1 1 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC37344.1 - 0.0032 16.9 0.1 0.0094 15.4 0.1 1.8 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC37344.1 - 0.13 12.4 1.0 0.46 10.6 0.1 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGC37344.1 - 0.22 11.0 0.1 1.1 8.8 0.0 2.2 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGC37344.1 - 0.24 10.7 0.0 0.51 9.6 0.0 1.5 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC37344.1 - 0.3 11.0 0.3 1.2 9.0 0.2 1.9 1 1 0 1 1 1 0 AAA ATPase domain ABC_membrane_3 PF13748.1 EGC37344.1 - 2.7 6.9 14.7 0.064 12.2 4.6 2.3 2 1 0 2 2 2 0 ABC transporter transmembrane region AIG1 PF04548.11 EGC37346.1 - 2.1e-09 36.7 1.6 2.1e-09 36.7 1.1 2.7 2 1 0 2 2 2 1 AIG1 family MMR_HSR1 PF01926.18 EGC37346.1 - 3.2e-09 36.7 0.6 3.2e-09 36.7 0.4 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC37346.1 - 5.2e-05 22.7 0.2 5.2e-05 22.7 0.2 2.6 2 1 1 3 3 3 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC37346.1 - 0.00071 19.7 1.7 0.034 14.2 0.0 2.9 2 1 0 2 2 2 1 AAA domain ABC_tran PF00005.22 EGC37346.1 - 0.0016 18.7 0.1 0.0016 18.7 0.0 3.1 2 1 0 2 2 1 1 ABC transporter AAA_29 PF13555.1 EGC37346.1 - 0.0025 17.3 0.1 0.0057 16.1 0.1 1.6 1 0 0 1 1 1 1 P-loop containing region of AAA domain PRK PF00485.13 EGC37346.1 - 0.0035 16.9 0.1 0.012 15.1 0.1 2.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_10 PF12846.2 EGC37346.1 - 0.006 16.0 1.3 0.033 13.6 0.1 2.1 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 EGC37346.1 - 0.011 15.4 0.1 0.14 11.7 0.0 2.3 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EGC37346.1 - 0.014 15.4 0.0 0.035 14.0 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain T2SE PF00437.15 EGC37346.1 - 0.022 13.6 0.9 0.055 12.3 0.6 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA PF00004.24 EGC37346.1 - 0.024 14.8 1.2 0.59 10.3 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Dynamin_N PF00350.18 EGC37346.1 - 0.6 9.9 0.0 0.29 10.9 0.1 6.4 4 1 0 4 4 3 0 Dynamin family SWIRM PF04433.12 EGC37347.1 - 2.2e-21 75.7 0.1 2.2e-21 75.7 0.1 3.2 3 0 0 3 3 3 1 SWIRM domain Myb_DNA-binding PF00249.26 EGC37347.1 - 3e-20 71.9 2.1 3.5e-10 39.7 0.1 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain JAB PF01398.16 EGC37347.1 - 3.3e-14 52.5 0.0 1e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 JAB1/Mov34/MPN/PAD-1 ubiquitin protease Myb_DNA-bind_6 PF13921.1 EGC37347.1 - 3.6e-08 33.3 11.7 1.2e-05 25.3 0.2 4.3 3 1 0 3 3 3 2 Myb-like DNA-binding domain Prok-JAB PF14464.1 EGC37347.1 - 2.5e-07 30.1 0.1 1.5e-06 27.6 0.1 2.0 1 1 0 1 1 1 1 Prokaryotic homologs of the JAB domain DUF1777 PF08648.7 EGC37347.1 - 0.00065 19.4 42.8 0.00065 19.4 29.7 3.5 3 0 0 3 3 3 2 Protein of unknown function (DUF1777) Beta-Casp PF10996.3 EGC37349.1 - 2.1e-24 85.8 0.0 1.3e-23 83.3 0.0 2.3 3 0 0 3 3 3 1 Beta-Casp domain RMMBL PF07521.7 EGC37349.1 - 7.6e-17 60.8 0.1 2.3e-16 59.3 0.0 1.9 2 0 0 2 2 2 1 RNA-metabolising metallo-beta-lactamase Lactamase_B PF00753.22 EGC37349.1 - 1.1e-16 61.0 0.2 2.9e-16 59.6 0.1 1.7 1 1 0 1 1 1 1 Metallo-beta-lactamase superfamily Lactamase_B_2 PF12706.2 EGC37349.1 - 3.6e-12 46.2 1.7 2.7e-10 40.1 0.2 2.4 2 1 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGC37349.1 - 4.2e-05 23.3 0.0 0.00026 20.7 0.0 2.3 2 2 0 2 2 2 1 Beta-lactamase superfamily domain DUF2373 PF10180.4 EGC37349.1 - 7.8 6.1 6.7 1.6 8.3 2.1 1.7 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2373) dNK PF01712.14 EGC37350.1 - 1.8e-32 112.2 4.2 3.1e-32 111.5 2.9 1.4 1 0 0 1 1 1 1 Deoxynucleoside kinase AAA_18 PF13238.1 EGC37350.1 - 1e-09 38.8 0.0 1.6e-09 38.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC37350.1 - 7.6e-09 36.4 0.0 6.4e-08 33.4 0.0 2.1 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EGC37350.1 - 3.3e-08 33.1 0.4 1.8e-05 24.2 0.1 2.3 2 0 0 2 2 2 2 Thymidylate kinase AAA_33 PF13671.1 EGC37350.1 - 3.7e-06 26.8 0.0 6.5e-06 26.0 0.0 1.4 1 1 0 1 1 1 1 AAA domain SKI PF01202.17 EGC37350.1 - 5.3e-05 23.1 1.1 0.036 13.9 0.1 2.3 2 0 0 2 2 2 2 Shikimate kinase UPF0079 PF02367.12 EGC37350.1 - 0.00078 19.0 1.0 0.016 14.8 0.0 2.5 1 1 2 3 3 3 1 Uncharacterised P-loop hydrolase UPF0079 AAA_28 PF13521.1 EGC37350.1 - 0.00089 19.2 0.0 0.0012 18.8 0.0 1.3 1 0 0 1 1 1 1 AAA domain Herpes_TK PF00693.13 EGC37350.1 - 0.0012 18.0 0.0 0.0021 17.2 0.0 1.3 1 0 0 1 1 1 1 Thymidine kinase from herpesvirus AAA_29 PF13555.1 EGC37350.1 - 0.0022 17.4 0.1 0.036 13.5 0.0 2.2 2 0 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC37350.1 - 0.003 17.8 0.0 0.0062 16.8 0.0 1.5 1 1 0 1 1 1 1 ABC transporter Cytidylate_kin2 PF13189.1 EGC37350.1 - 0.0092 15.9 0.3 0.1 12.4 0.0 2.4 2 1 0 2 2 2 1 Cytidylate kinase-like family CoaE PF01121.15 EGC37350.1 - 0.012 15.0 0.0 0.28 10.5 0.0 2.2 2 0 0 2 2 2 0 Dephospho-CoA kinase AAA_22 PF13401.1 EGC37350.1 - 0.026 14.6 0.1 0.15 12.1 0.0 2.1 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC37350.1 - 0.037 14.0 0.5 0.082 12.8 0.3 1.9 1 1 0 1 1 1 0 AAA ATPase domain NTPase_1 PF03266.10 EGC37350.1 - 0.084 12.5 1.1 0.88 9.2 0.1 2.2 2 0 0 2 2 2 0 NTPase ATP_bind_1 PF03029.12 EGC37350.1 - 0.09 12.3 0.3 0.46 9.9 0.0 2.1 2 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_24 PF13479.1 EGC37350.1 - 0.19 11.2 1.4 0.52 9.8 0.3 2.0 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGC37350.1 - 0.19 11.6 1.4 1.7 8.5 0.0 2.3 2 1 0 2 2 2 0 AAA domain AAA_23 PF13476.1 EGC37350.1 - 2.5 8.3 7.3 9.9 6.4 5.1 1.9 1 1 0 1 1 1 0 AAA domain Lipase_3 PF01764.20 EGC37351.1 - 1.7e-21 76.3 0.0 8.9e-21 73.9 0.0 2.1 2 0 0 2 2 2 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGC37351.1 - 0.05 13.3 0.0 0.084 12.6 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF2048 PF09752.4 EGC37351.1 - 0.1 11.4 0.0 0.17 10.7 0.0 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2048) Abhydrolase_6 PF12697.2 EGC37351.1 - 0.33 10.7 0.0 0.47 10.2 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family SSP160 PF06933.6 EGC37351.1 - 1.5 6.6 12.7 2.8 5.7 8.8 1.3 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 CbiC PF02570.10 EGC37352.1 - 0.13 11.6 3.1 0.51 9.7 0.7 2.4 2 0 0 2 2 2 0 Precorrin-8X methylmutase EMP24_GP25L PF01105.19 EGC37353.1 - 1.9e-45 154.8 0.5 2.3e-45 154.5 0.4 1.1 1 0 0 1 1 1 1 emp24/gp25L/p24 family/GOLD TFIIS_M PF07500.9 EGC37355.1 - 6e-24 84.3 2.0 6e-24 84.3 1.4 1.8 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS), central domain TFIIS_C PF01096.13 EGC37355.1 - 1.5e-19 69.3 9.7 1.5e-19 69.3 6.8 1.9 2 0 0 2 2 2 1 Transcription factor S-II (TFIIS) Med26 PF08711.6 EGC37355.1 - 2.5e-12 46.0 2.8 5e-12 45.1 1.5 1.9 1 1 0 1 1 1 1 TFIIS helical bundle-like domain Flp_N PF03930.9 EGC37355.1 - 0.021 14.6 1.9 1.1 9.0 0.0 2.9 2 1 0 2 2 2 0 Recombinase Flp protein N-terminus DUF4423 PF14394.1 EGC37355.1 - 0.2 11.2 3.0 1.5 8.3 0.2 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4423) DnaJ PF00226.26 EGC37356.1 - 1.5e-20 72.6 0.1 2.8e-20 71.8 0.1 1.4 1 0 0 1 1 1 1 DnaJ domain Mito_carr PF00153.22 EGC37356.1 - 1.8e-08 33.9 0.0 0.0067 16.1 0.0 2.6 2 0 0 2 2 2 2 Mitochondrial carrier protein Z1 PF10593.4 EGC37357.1 - 0.0017 17.6 0.8 0.0017 17.6 0.6 2.8 3 0 0 3 3 3 1 Z1 domain Zip PF02535.17 EGC37357.1 - 3 6.7 24.8 0.44 9.5 8.3 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter VHP PF02209.14 EGC37358.1 - 1.2e-13 50.4 0.7 1.8e-13 49.9 0.5 1.3 1 0 0 1 1 1 1 Villin headpiece domain LSM PF01423.17 EGC37359.1 - 1.7e-17 62.6 1.4 2.4e-17 62.2 1.0 1.2 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC37359.1 - 0.0087 15.9 0.1 0.0087 15.9 0.1 1.6 2 0 0 2 2 2 1 Ataxin 2 SM domain Gemin7 PF11095.3 EGC37359.1 - 0.016 14.9 0.0 0.021 14.5 0.0 1.2 1 0 0 1 1 1 0 Gem-associated protein 7 (Gemin7) BPL_C PF02237.12 EGC37359.1 - 0.12 12.0 1.4 0.15 11.7 0.3 1.6 2 0 0 2 2 2 0 Biotin protein ligase C terminal domain PIF1 PF05970.9 EGC37360.1 - 1.2e-10 40.8 0.1 1.2e-10 40.8 0.1 2.4 3 0 0 3 3 2 1 PIF1-like helicase AAA_30 PF13604.1 EGC37360.1 - 4.7e-06 26.3 0.0 7.3e-06 25.6 0.0 1.2 1 0 0 1 1 1 1 AAA domain Mg_chelatase PF01078.16 EGC37360.1 - 0.00063 18.9 0.0 0.0015 17.7 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI PhoH PF02562.11 EGC37360.1 - 0.00066 18.9 0.0 0.0015 17.8 0.0 1.6 1 0 0 1 1 1 1 PhoH-like protein T2SE PF00437.15 EGC37360.1 - 0.0016 17.4 0.3 0.003 16.4 0.1 1.4 1 1 0 1 1 1 1 Type II/IV secretion system protein AAA_16 PF13191.1 EGC37360.1 - 0.0031 17.5 0.0 0.0049 16.8 0.0 1.2 1 0 0 1 1 1 1 AAA ATPase domain AAA_19 PF13245.1 EGC37360.1 - 0.0046 16.6 0.0 0.0069 16.1 0.0 1.2 1 0 0 1 1 1 1 Part of AAA domain NACHT PF05729.7 EGC37360.1 - 0.0061 16.2 0.0 0.011 15.4 0.0 1.4 1 0 0 1 1 1 1 NACHT domain AAA_22 PF13401.1 EGC37360.1 - 0.0095 16.0 0.7 0.019 15.0 0.0 1.8 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC37360.1 - 0.013 14.8 0.0 0.023 14.1 0.0 1.3 1 0 0 1 1 1 0 AAA domain DEAD PF00270.24 EGC37360.1 - 0.026 14.0 0.0 0.06 12.8 0.0 1.6 1 0 0 1 1 1 0 DEAD/DEAH box helicase IstB_IS21 PF01695.12 EGC37360.1 - 0.058 12.8 0.0 0.1 11.9 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein FtsK_SpoIIIE PF01580.13 EGC37360.1 - 0.073 12.5 0.0 0.11 11.9 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EGC37360.1 - 0.23 12.2 1.4 0.73 10.6 0.0 2.4 2 1 0 2 2 2 0 AAA domain ABC_tran PF00005.22 EGC37360.1 - 0.27 11.5 0.0 0.27 11.5 0.0 2.5 2 1 0 2 2 1 0 ABC transporter SprA-related PF12118.3 EGC37360.1 - 1.5 8.1 11.4 1.8 7.7 7.9 1.1 1 0 0 1 1 1 0 SprA-related family DUF506 PF04720.7 EGC37360.1 - 2.8 7.5 7.1 5.7 6.5 4.9 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF506) PA14 PF07691.7 EGC37361.1 - 3e-10 39.9 0.3 5.4e-10 39.0 0.2 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC37361.1 - 0.015 15.1 1.8 0.015 15.1 1.3 12.1 12 2 0 12 12 12 0 Dictyostelium (slime mold) repeat Mss4 PF04421.8 EGC37362.1 - 3.9e-16 58.6 0.2 5.8e-16 58.1 0.1 1.5 1 1 0 1 1 1 1 Mss4 protein Yippee-Mis18 PF03226.9 EGC37362.1 - 0.026 14.5 3.8 0.98 9.5 2.7 2.3 1 1 1 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly A2L_zn_ribbon PF08792.5 EGC37362.1 - 0.2 11.1 0.1 0.2 11.1 0.1 1.8 2 0 0 2 2 2 0 A2L zinc ribbon domain DNA_RNApol_7kD PF03604.8 EGC37362.1 - 8.6 5.9 8.0 16 5.0 0.7 3.0 3 0 0 3 3 3 0 DNA directed RNA polymerase, 7 kDa subunit Ribosomal_L14e PF01929.12 EGC37364.1 - 1.2e-19 70.4 4.0 2.9e-19 69.1 2.8 1.7 1 0 0 1 1 1 1 Ribosomal protein L14 TPR_14 PF13428.1 EGC37364.1 - 4.7e-08 32.9 0.0 0.026 15.1 0.0 6.6 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37364.1 - 1.1e-07 31.7 0.2 0.014 15.2 0.0 3.9 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_15 PF13429.1 EGC37364.1 - 1.2e-07 31.1 3.8 0.00014 21.0 0.0 4.5 4 1 0 4 4 4 1 Tetratricopeptide repeat Suf PF05843.9 EGC37364.1 - 6.4e-07 29.3 36.7 0.13 11.9 0.2 7.1 2 2 4 6 6 6 4 Suppressor of forked protein (Suf) TPR_19 PF14559.1 EGC37364.1 - 2.7e-06 27.6 0.7 0.25 11.7 0.0 4.8 5 1 1 6 6 5 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGC37364.1 - 6.3e-06 25.9 14.4 0.39 10.4 0.0 7.2 7 1 0 7 7 7 2 Mad3/BUB1 homology region 1 TPR_11 PF13414.1 EGC37364.1 - 1.6e-05 24.4 0.1 0.32 10.6 0.0 4.7 5 1 0 5 5 5 1 TPR repeat TPR_2 PF07719.12 EGC37364.1 - 4.7e-05 22.9 2.1 0.0086 15.9 0.2 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC37364.1 - 0.0015 18.1 0.2 0.95 9.4 0.0 4.4 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37364.1 - 0.013 15.2 5.0 0.27 11.1 0.1 4.0 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37364.1 - 0.014 14.9 1.4 0.56 9.9 0.1 3.7 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37364.1 - 0.018 15.7 0.2 5.1 7.8 0.0 4.1 5 0 0 5 5 3 0 Tetratricopeptide repeat HAT PF02184.11 EGC37364.1 - 2.4 7.9 9.8 1.3 8.8 0.1 4.9 4 0 0 4 4 4 0 HAT (Half-A-TPR) repeat FNIP PF05725.7 EGC37365.1 - 1.1e-66 220.5 84.9 3.9e-06 26.6 1.1 17.0 3 2 21 24 24 24 24 FNIP Repeat zf-B_box PF00643.19 EGC37365.1 - 4.6e-05 23.2 4.5 7.9e-05 22.4 3.1 1.4 1 0 0 1 1 1 1 B-box zinc finger Glyco_hydro_114 PF03537.8 EGC37365.1 - 0.00027 20.6 7.9 4.7 7.0 0.0 7.4 4 3 6 10 10 10 2 Glycoside-hydrolase family GH114 zf-UBR PF02207.15 EGC37365.1 - 0.27 11.0 3.2 0.6 9.8 2.2 1.6 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) polyprenyl_synt PF00348.12 EGC37367.1 - 4.7e-40 137.0 0.0 6.7e-40 136.5 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase ResIII PF04851.10 EGC37368.1 - 2.3e-07 30.8 1.4 2.3e-07 30.8 0.9 6.0 4 3 1 5 5 5 1 Type III restriction enzyme, res subunit AAA_18 PF13238.1 EGC37369.1 - 0.00011 22.4 1.4 0.00022 21.5 0.8 1.7 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC37369.1 - 0.00029 20.7 0.0 0.0014 18.5 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC37369.1 - 0.028 15.2 0.2 0.27 12.0 0.2 2.3 1 1 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGC37369.1 - 0.029 14.3 0.0 0.042 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EGC37369.1 - 0.064 12.6 1.5 4 6.7 1.0 2.4 1 1 0 1 1 1 0 Thymidylate kinase Zeta_toxin PF06414.7 EGC37369.1 - 0.092 11.8 0.0 0.23 10.5 0.0 1.6 1 0 0 1 1 1 0 Zeta toxin MinC_C PF03775.11 EGC37370.1 - 4.3e-27 93.8 0.1 8.6e-27 92.8 0.0 1.5 1 0 0 1 1 1 1 Septum formation inhibitor MinC, C-terminal domain MinC_N PF05209.8 EGC37370.1 - 6.6e-12 45.0 0.2 1.3e-11 44.0 0.1 1.4 1 0 0 1 1 1 1 Septum formation inhibitor MinC, N-terminal domain MutS_V PF00488.16 EGC37370.1 - 0.018 14.4 0.2 0.026 13.9 0.1 1.3 1 0 0 1 1 1 0 MutS domain V RNA_pol_Rpb8 PF03870.10 EGC37371.1 - 4.8e-46 156.3 0.2 5.4e-46 156.2 0.1 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb8 Acetyltransf_1 PF00583.19 EGC37372.1 - 0.00025 21.0 0.0 0.0054 16.7 0.0 2.3 1 1 1 2 2 2 2 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC37372.1 - 0.082 13.0 0.5 0.98 9.6 0.1 2.5 2 1 0 2 2 2 0 Acetyltransferase (GNAT) domain TM2 PF05154.11 EGC37374.1 - 6.7e-15 55.0 14.1 9.6e-15 54.5 9.8 1.2 1 0 0 1 1 1 1 TM2 domain DUF2946 PF11162.3 EGC37374.1 - 0.4 10.8 9.0 0.23 11.6 5.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2946) MatE PF01554.13 EGC37376.1 - 4.9e-52 175.8 28.8 1e-31 109.7 8.2 2.9 4 0 0 4 4 4 2 MatE Polysacc_synt_C PF14667.1 EGC37376.1 - 5.4e-05 23.0 14.5 0.00015 21.5 2.7 4.2 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain ETRAMP PF09716.5 EGC37376.1 - 0.00068 19.5 0.0 5.3 7.0 0.0 4.1 3 1 0 3 3 3 1 Malarial early transcribed membrane protein (ETRAMP) HATPase_c PF02518.21 EGC37377.1 - 9.9e-29 99.2 0.2 2.4e-28 98.0 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC37377.1 - 9.6e-25 86.7 0.1 6.6e-24 84.0 0.0 2.4 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGC37377.1 - 1.1e-17 63.7 0.0 2.2e-17 62.7 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 EGC37377.1 - 0.00012 21.8 0.0 0.00043 20.0 0.0 2.0 2 0 0 2 2 2 1 PAS domain PAS PF00989.19 EGC37377.1 - 0.054 13.2 0.0 0.18 11.6 0.0 1.8 1 1 0 1 1 1 0 PAS fold Phlebovirus_G1 PF07243.6 EGC37377.1 - 1.4 6.9 5.8 2.3 6.2 4.0 1.3 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 zf-DHHC PF01529.15 EGC37378.1 - 7.1e-43 146.0 9.0 7.1e-43 146.0 6.2 3.3 2 1 1 3 3 3 1 DHHC palmitoyltransferase Voltage_CLC PF00654.15 EGC37379.1 - 1.6e-109 366.2 23.3 2.3e-109 365.6 11.9 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EGC37379.1 - 9.8e-21 73.2 0.4 2.9e-09 36.5 0.0 2.5 2 0 0 2 2 2 2 CBS domain DUF1691 PF07950.6 EGC37379.1 - 0.064 13.1 0.0 0.28 11.1 0.0 2.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1691) TAT_signal PF10518.4 EGC37379.1 - 0.7 10.0 8.4 0.062 13.3 0.9 2.8 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence DUF3550 PF12070.3 EGC37381.1 - 4.5e-155 517.2 12.1 4.5e-155 517.2 8.4 2.1 2 1 0 2 2 2 1 Protein of unknown function (DUF3550/UPF0682) Profilin PF00235.14 EGC37382.1 - 1.7e-05 24.9 0.0 3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Profilin Zip PF02535.17 EGC37382.1 - 0.029 13.3 1.1 0.039 12.9 0.7 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter GEMIN8 PF15348.1 EGC37382.1 - 0.096 12.7 12.6 0.13 12.2 8.7 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 Pox_RNA_Pol_19 PF05320.7 EGC37382.1 - 0.33 10.7 10.8 0.26 11.0 6.5 1.5 1 1 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Hid1 PF12722.2 EGC37382.1 - 2.6 5.6 10.8 3 5.4 7.5 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Ycf1 PF05758.7 EGC37382.1 - 5.2 4.6 13.9 6.4 4.3 9.7 1.1 1 0 0 1 1 1 0 Ycf1 Cwf_Cwc_15 PF04889.7 EGC37382.1 - 7 6.2 23.5 9.8 5.8 16.3 1.1 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Rota_VP2 PF05087.7 EGC37382.1 - 7.5 4.3 14.3 8.2 4.2 9.9 1.1 1 0 0 1 1 1 0 Rotavirus VP2 protein Ribosomal_L33 PF00471.15 EGC37383.1 - 8.5e-16 57.9 0.8 1e-15 57.7 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein L33 V-ATPase_G PF03179.10 EGC37384.1 - 6e-30 103.6 15.0 6.7e-30 103.4 10.4 1.0 1 0 0 1 1 1 1 Vacuolar (H+)-ATPase G subunit Bacillus_HBL PF05791.6 EGC37384.1 - 0.00053 19.4 4.2 0.00065 19.1 2.9 1.2 1 0 0 1 1 1 1 Bacillus haemolytic enterotoxin (HBL) DUF3829 PF12889.2 EGC37384.1 - 0.0014 17.9 8.6 0.0015 17.8 6.0 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3829) DUF3552 PF12072.3 EGC37384.1 - 0.0018 17.4 11.5 0.0018 17.4 8.0 2.0 1 1 1 2 2 2 1 Domain of unknown function (DUF3552) MscS_porin PF12795.2 EGC37384.1 - 0.013 14.7 8.3 0.018 14.4 5.7 1.2 1 0 0 1 1 1 0 Mechanosensitive ion channel porin domain ATP-synt_B PF00430.13 EGC37384.1 - 0.015 15.0 17.8 0.11 12.3 5.8 2.0 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) Mod_r PF07200.8 EGC37384.1 - 0.02 14.8 7.5 0.026 14.4 5.2 1.3 1 0 0 1 1 1 0 Modifier of rudimentary (Mod(r)) protein Vfa1 PF08432.5 EGC37384.1 - 0.03 14.3 12.9 0.035 14.1 9.0 1.0 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phage_Gp23 PF10669.4 EGC37384.1 - 0.061 13.4 3.5 0.077 13.1 2.4 1.3 1 0 0 1 1 1 0 Protein gp23 (Bacteriophage A118) HSD3 PF15244.1 EGC37384.1 - 0.071 12.3 6.6 0.085 12.0 4.6 1.1 1 0 0 1 1 1 0 Hydroxy-steroid dehydrogenase TPR_MLP1_2 PF07926.7 EGC37384.1 - 0.085 12.6 9.6 0.15 11.7 6.5 1.5 1 1 0 1 1 1 0 TPR/MLP1/MLP2-like protein Mnd1 PF03962.10 EGC37384.1 - 0.12 12.0 9.7 0.14 11.7 6.7 1.1 1 0 0 1 1 1 0 Mnd1 family Tnp_P_element PF12017.3 EGC37384.1 - 0.13 11.5 2.7 0.16 11.1 1.9 1.1 1 0 0 1 1 1 0 Transposase protein FliD_N PF02465.13 EGC37384.1 - 0.13 12.5 4.5 0.19 12.0 3.1 1.3 1 0 0 1 1 1 0 Flagellar hook-associated protein 2 N-terminus Striatin PF08232.7 EGC37384.1 - 0.23 11.7 8.7 0.28 11.4 6.0 1.1 1 0 0 1 1 1 0 Striatin family cwf18 PF08315.7 EGC37384.1 - 0.27 11.7 8.8 0.34 11.3 6.1 1.2 1 0 0 1 1 1 0 cwf18 pre-mRNA splicing factor PEP-utilisers_N PF05524.8 EGC37384.1 - 0.27 11.0 5.4 0.43 10.3 3.7 1.3 1 1 0 1 1 1 0 PEP-utilising enzyme, N-terminal ArsC PF03960.10 EGC37384.1 - 0.29 11.2 4.2 0.39 10.8 2.1 1.7 1 1 1 2 2 2 0 ArsC family Cytidylate_kin2 PF13189.1 EGC37384.1 - 0.31 10.9 5.0 0.33 10.8 3.1 1.3 1 1 0 1 1 1 0 Cytidylate kinase-like family FlgM PF04316.8 EGC37384.1 - 0.34 10.9 9.1 0.66 9.9 2.1 2.5 2 1 0 2 2 2 0 Anti-sigma-28 factor, FlgM Atg14 PF10186.4 EGC37384.1 - 0.34 9.8 7.9 0.38 9.6 5.4 1.1 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2072 PF09845.4 EGC37384.1 - 0.35 10.7 4.4 0.49 10.3 3.0 1.3 1 0 0 1 1 1 0 Zn-ribbon containing protein (DUF2072) CagY_I PF14585.1 EGC37384.1 - 0.36 10.7 4.4 0.59 10.0 3.0 1.5 1 1 0 1 1 1 0 CagY type 1 repeat CPSase_L_D3 PF02787.14 EGC37384.1 - 0.37 10.5 4.7 0.68 9.7 3.3 1.5 1 1 0 1 1 1 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain DivIVA PF05103.8 EGC37384.1 - 0.39 10.7 15.3 1.6 8.7 7.6 2.1 1 1 1 2 2 2 0 DivIVA protein DUF1098 PF06497.6 EGC37384.1 - 0.41 10.7 2.9 2.9 8.0 0.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1098) DUF4407 PF14362.1 EGC37384.1 - 0.45 9.4 12.3 6 5.7 0.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4407) DUF4570 PF15134.1 EGC37384.1 - 0.46 10.3 5.5 0.44 10.4 1.7 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4570) YlqD PF11068.3 EGC37384.1 - 0.56 10.2 8.3 0.65 10.0 5.7 1.2 1 0 0 1 1 1 0 YlqD protein vATP-synt_E PF01991.13 EGC37384.1 - 0.62 9.3 20.3 1.4 8.1 8.2 1.9 1 1 0 2 2 2 0 ATP synthase (E/31 kDa) subunit DUF2203 PF09969.4 EGC37384.1 - 0.62 10.2 5.2 0.91 9.7 3.6 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) RRF PF01765.14 EGC37384.1 - 0.75 9.2 11.5 1.3 8.4 7.9 1.4 1 1 0 1 1 1 0 Ribosome recycling factor IncA PF04156.9 EGC37384.1 - 0.84 9.2 9.0 1.4 8.4 6.3 1.5 1 1 0 1 1 1 0 IncA protein HrpE PF06188.7 EGC37384.1 - 0.93 9.2 8.6 4.2 7.0 5.9 1.8 1 1 0 1 1 1 0 HrpE/YscL/FliH and V-type ATPase subunit E APG6 PF04111.7 EGC37384.1 - 1.5 7.7 10.3 1.6 7.6 7.1 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 4HB_MCP_1 PF12729.2 EGC37384.1 - 1.8 7.8 12.6 38 3.5 8.7 2.2 1 1 0 1 1 1 0 Four helix bundle sensory module for signal transduction COG2 PF06148.6 EGC37384.1 - 2.6 7.9 6.7 14 5.5 1.3 2.1 1 1 1 2 2 2 0 COG (conserved oligomeric Golgi) complex component, COG2 DUF4446 PF14584.1 EGC37384.1 - 2.9 7.7 9.3 5.6 6.7 2.8 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) eIF3_N PF09440.5 EGC37384.1 - 2.9 8.0 8.1 4.6 7.4 5.6 1.4 1 1 0 1 1 1 0 eIF3 subunit 6 N terminal domain LUC7 PF03194.10 EGC37384.1 - 4.9 6.5 9.9 5.4 6.4 6.9 1.1 1 0 0 1 1 1 0 LUC7 N_terminus FIVAR PF07554.8 EGC37384.1 - 5 7.4 8.4 8.7 6.7 1.5 2.6 2 1 0 2 2 2 0 Uncharacterised Sugar-binding Domain DUF883 PF05957.8 EGC37384.1 - 6.3 7.2 8.0 11 6.5 3.3 2.0 1 1 1 2 2 2 0 Bacterial protein of unknown function (DUF883) KfrA_N PF11740.3 EGC37384.1 - 7.6 7.0 9.2 6.2 7.3 1.8 2.1 1 1 1 2 2 2 0 Plasmid replication region DNA-binding N-term TMF_DNA_bd PF12329.3 EGC37384.1 - 9.5 6.1 16.5 1.9 8.3 6.9 2.5 2 1 0 2 2 2 0 TATA element modulatory factor 1 DNA binding COX6C PF02937.10 EGC37385.1 - 0.0012 18.7 0.0 0.0012 18.6 0.0 1.0 1 0 0 1 1 1 1 Cytochrome c oxidase subunit VIc Dicty_CTDC PF00526.13 EGC37386.1 - 5.7e-283 910.3 845.6 1.2e-10 41.0 10.9 44.5 44 0 0 44 44 44 43 Dictyostelium (slime mold) repeat AAA_18 PF13238.1 EGC37387.1 - 3e-09 37.2 1.8 1.1e-07 32.2 1.2 2.3 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC37387.1 - 1.9e-06 28.6 3.3 7.5e-06 26.7 2.3 2.1 1 1 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGC37387.1 - 0.00011 22.3 0.0 0.00026 21.1 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_33 PF13671.1 EGC37387.1 - 0.00023 21.0 0.0 0.00031 20.6 0.0 1.6 1 1 0 1 1 1 1 AAA domain KAP_NTPase PF07693.9 EGC37387.1 - 0.0014 17.7 0.0 0.0018 17.3 0.0 1.2 1 0 0 1 1 1 1 KAP family P-loop domain NTPase_1 PF03266.10 EGC37387.1 - 0.0019 17.9 0.0 0.0033 17.1 0.0 1.3 1 0 0 1 1 1 1 NTPase AAA_22 PF13401.1 EGC37387.1 - 0.002 18.2 0.0 0.0027 17.8 0.0 1.5 1 1 0 1 1 1 1 AAA domain ArgK PF03308.11 EGC37387.1 - 0.0029 16.4 0.0 0.0044 15.8 0.0 1.2 1 0 0 1 1 1 1 ArgK protein AAA PF00004.24 EGC37387.1 - 0.0043 17.2 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC37387.1 - 0.0048 16.9 0.0 0.008 16.1 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGC37387.1 - 0.0048 16.7 1.1 0.028 14.3 0.0 2.3 2 1 0 2 2 2 1 AAA domain NB-ARC PF00931.17 EGC37387.1 - 0.0083 15.0 0.0 0.021 13.7 0.0 1.6 1 1 0 1 1 1 1 NB-ARC domain KTI12 PF08433.5 EGC37387.1 - 0.009 15.2 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 Chromatin associated protein KTI12 Zeta_toxin PF06414.7 EGC37387.1 - 0.0093 15.0 0.0 0.049 12.7 0.0 2.0 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 EGC37387.1 - 0.011 15.4 0.0 0.032 13.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain (dynein-related subfamily) PRK PF00485.13 EGC37387.1 - 0.012 15.2 0.0 0.15 11.6 0.0 2.1 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Guanylate_kin PF00625.16 EGC37387.1 - 0.017 14.6 0.0 0.2 11.0 0.0 2.2 2 0 0 2 2 2 0 Guanylate kinase DUF258 PF03193.11 EGC37387.1 - 0.024 13.7 0.1 0.036 13.2 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF258 ABC_tran PF00005.22 EGC37387.1 - 0.027 14.7 0.0 0.038 14.2 0.0 1.3 1 0 0 1 1 1 0 ABC transporter UPF0449 PF15136.1 EGC37387.1 - 0.032 14.4 0.0 0.096 12.9 0.0 1.8 2 0 0 2 2 2 0 Uncharacterised protein family UPF0449 RuvB_N PF05496.7 EGC37387.1 - 0.052 12.5 0.0 0.081 11.9 0.0 1.2 1 0 0 1 1 1 0 Holliday junction DNA helicase ruvB N-terminus ADK PF00406.17 EGC37387.1 - 0.09 12.6 0.0 1.2 8.9 0.0 2.5 2 1 0 2 2 2 0 Adenylate kinase Methyltransf_12 PF08242.7 EGC37387.1 - 3.6 8.1 7.1 1.3 9.4 2.8 2.0 2 1 0 2 2 1 0 Methyltransferase domain Actin PF00022.14 EGC37388.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC37388.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF837 PF05769.6 EGC37389.1 - 0.019 14.5 0.1 0.06 12.8 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF837) CM1 PF03026.10 EGC37390.1 - 0.14 11.2 0.0 0.14 11.2 0.0 1.1 1 0 0 1 1 1 0 Influenza C virus M1 protein PLDc_3 PF13918.1 EGC37391.1 - 3.2e-32 111.4 0.3 3.2e-30 104.8 0.3 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc_2 PF13091.1 EGC37391.1 - 5.8e-32 110.0 0.0 1.7e-18 66.5 0.0 2.2 2 0 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGC37391.1 - 1.3e-10 40.7 0.2 9.7e-06 25.2 0.0 2.7 2 0 0 2 2 2 2 Phospholipase D Active site motif WD40 PF00400.27 EGC37392.1 - 6.6e-07 28.9 0.0 0.0026 17.5 0.0 3.2 3 0 0 3 3 3 2 WD domain, G-beta repeat CPSF_A PF03178.10 EGC37392.1 - 5.6e-05 22.3 0.5 0.0044 16.1 0.3 2.2 1 1 0 1 1 1 1 CPSF A subunit region DUF1513 PF07433.6 EGC37392.1 - 0.077 11.8 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1513) DUF1548 PF07579.6 EGC37394.1 - 0.091 12.8 0.0 0.099 12.7 0.0 1.0 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1548) Methyltransf_7 PF03492.10 EGC37396.1 - 1.9e-17 63.0 9.5 6.1e-17 61.3 6.6 1.7 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.7 EGC37396.1 - 0.0012 19.3 0.0 0.0068 16.8 0.0 2.3 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC37396.1 - 0.023 15.1 0.0 0.071 13.5 0.0 1.9 1 0 0 1 1 1 0 Methyltransferase domain BRCT PF00533.21 EGC37397.1 - 3.2e-09 36.8 0.9 1.2e-08 34.9 0.6 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain DEP PF00610.16 EGC37397.1 - 0.016 14.9 0.0 0.038 13.7 0.0 1.6 1 0 0 1 1 1 0 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Crust_neurohorm PF01147.12 EGC37397.1 - 0.056 12.7 1.4 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 Crustacean CHH/MIH/GIH neurohormone family PTCB-BRCT PF12738.2 EGC37397.1 - 0.095 12.5 0.1 0.24 11.2 0.1 1.7 1 0 0 1 1 1 0 twin BRCT domain Cep57_CLD_2 PF14197.1 EGC37397.1 - 8.7 6.3 19.3 0.17 11.8 1.6 3.9 3 0 0 3 3 3 0 Centrosome localisation domain of PPC89 eIF-5_eIF-2B PF01873.12 EGC37399.1 - 6.4e-41 138.9 0.6 1.4e-40 137.8 0.4 1.5 1 0 0 1 1 1 1 Domain found in IF2B/IF5 Arc_trans_TRASH PF08394.5 EGC37399.1 - 0.0082 16.2 1.9 0.0082 16.2 1.3 2.5 1 1 1 2 2 2 1 Archaeal TRASH domain Mem_trans PF03547.13 EGC37399.1 - 0.0086 14.4 3.4 0.011 14.0 2.3 1.1 1 0 0 1 1 1 1 Membrane transport protein SART-1 PF03343.8 EGC37399.1 - 0.014 13.8 26.9 0.015 13.6 18.6 1.1 1 0 0 1 1 1 0 SART-1 family TF_Zn_Ribbon PF08271.7 EGC37399.1 - 0.016 14.4 1.1 0.041 13.2 0.8 1.7 1 0 0 1 1 1 0 TFIIB zinc-binding PLRV_ORF5 PF01690.12 EGC37399.1 - 0.35 9.9 14.2 0.39 9.8 9.9 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein Daxx PF03344.10 EGC37399.1 - 0.36 9.2 19.7 0.4 9.0 13.6 1.1 1 0 0 1 1 1 0 Daxx Family Neur_chan_memb PF02932.11 EGC37399.1 - 0.42 10.4 9.3 0.56 10.0 6.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_S46 PF10459.4 EGC37399.1 - 0.81 8.0 12.6 0.89 7.8 8.7 1.1 1 0 0 1 1 1 0 Peptidase S46 LMBR1 PF04791.11 EGC37399.1 - 2.3 6.6 6.3 2.4 6.6 4.4 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein Hid1 PF12722.2 EGC37399.1 - 9.7 3.7 16.0 11 3.5 11.1 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Actin PF00022.14 EGC37400.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC37400.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) COesterase PF00135.23 EGC37401.1 - 8.3e-110 368.0 1.3 9.4e-110 367.8 0.9 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC37401.1 - 9.1e-08 31.9 0.1 2e-07 30.8 0.1 1.6 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC37401.1 - 0.00064 19.4 0.1 0.0011 18.7 0.1 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGC37401.1 - 0.011 15.2 0.1 0.016 14.6 0.0 1.3 1 0 0 1 1 1 0 Putative esterase tRNA-synt_1b PF00579.20 EGC37402.1 - 3e-73 246.5 0.1 6.3e-73 245.4 0.0 1.6 1 1 0 1 1 1 1 tRNA synthetases class I (W and Y) Pyridoxal_deC PF00282.14 EGC37404.1 - 4e-13 48.5 0.0 5.7e-09 34.8 0.0 3.0 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain SapB_1 PF05184.10 EGC37405.1 - 1e-18 66.6 15.3 9.4e-10 38.0 2.7 3.0 2 0 0 2 2 2 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC37405.1 - 5.9e-16 58.1 11.8 1.4e-09 37.7 2.4 3.0 2 0 0 2 2 2 2 Saposin-like type B, region 2 TcpQ PF10671.4 EGC37406.1 - 0.087 12.7 0.3 1.7 8.6 0.1 2.3 2 0 0 2 2 2 0 Toxin co-regulated pilus biosynthesis protein Q Pinin_SDK_memA PF04696.8 EGC37406.1 - 0.23 11.0 5.7 0.094 12.3 0.9 2.2 1 1 1 2 2 2 0 pinin/SDK/memA/ protein conserved region Complex1_LYR PF05347.10 EGC37407.1 - 7.2e-13 48.1 0.2 9.4e-13 47.7 0.2 1.1 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC37407.1 - 3.9e-09 36.5 0.1 4.9e-09 36.2 0.1 1.1 1 0 0 1 1 1 1 Complex1_LYR-like IBN_N PF03810.14 EGC37408.1 - 7.1e-11 41.8 0.7 1e-09 38.1 0.1 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGC37408.1 - 0.012 15.4 3.9 0.21 11.5 0.1 4.3 4 1 0 4 4 4 0 Exportin 1-like protein HEAT_2 PF13646.1 EGC37408.1 - 0.019 15.2 0.0 0.99 9.7 0.0 3.2 2 1 1 3 3 3 0 HEAT repeats NAD_binding_10 PF13460.1 EGC37409.1 - 8.9e-07 29.0 0.0 1.4e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC37409.1 - 2.8e-05 23.6 0.0 3.7e-05 23.2 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Semialdhyde_dh PF01118.19 EGC37409.1 - 0.00059 20.1 0.0 0.001 19.3 0.0 1.4 1 0 0 1 1 1 1 Semialdehyde dehydrogenase, NAD binding domain DapB_N PF01113.15 EGC37409.1 - 0.00064 19.6 0.0 0.0012 18.7 0.0 1.5 1 0 0 1 1 1 1 Dihydrodipicolinate reductase, N-terminus NAD_binding_4 PF07993.7 EGC37409.1 - 0.003 16.5 0.0 0.0043 16.0 0.0 1.3 1 1 0 1 1 1 1 Male sterility protein Polysacc_synt_2 PF02719.10 EGC37409.1 - 0.0038 16.1 0.0 0.0059 15.5 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC37409.1 - 0.005 16.7 0.0 0.0079 16.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase NmrA PF05368.8 EGC37409.1 - 0.007 15.6 0.0 0.017 14.3 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGC37409.1 - 0.0095 14.6 0.0 0.014 14.1 0.0 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Saccharop_dh PF03435.13 EGC37409.1 - 0.018 14.0 0.3 3.6 6.4 0.0 2.1 2 0 0 2 2 2 0 Saccharopine dehydrogenase CTP_transf_2 PF01467.21 EGC37409.1 - 0.055 13.5 0.0 0.082 12.9 0.0 1.3 1 0 0 1 1 1 0 Cytidylyltransferase DUF4357 PF14267.1 EGC37409.1 - 0.55 9.8 5.0 1.3 8.7 3.4 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4357) NAD_binding_10 PF13460.1 EGC37410.1 - 4.1e-06 26.9 0.0 5.8e-06 26.4 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC37410.1 - 0.00029 20.3 0.0 0.00039 19.9 0.0 1.2 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC37410.1 - 0.0029 16.5 0.1 0.0044 15.9 0.0 1.3 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Semialdhyde_dh PF01118.19 EGC37410.1 - 0.0036 17.5 0.0 0.0094 16.2 0.0 1.6 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_4 PF07993.7 EGC37410.1 - 0.012 14.5 0.0 0.021 13.7 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein DapB_N PF01113.15 EGC37410.1 - 0.018 14.9 0.1 0.044 13.6 0.0 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EGC37410.1 - 0.019 14.8 0.0 0.031 14.2 0.0 1.2 1 0 0 1 1 1 0 short chain dehydrogenase 3Beta_HSD PF01073.14 EGC37410.1 - 0.021 13.5 0.0 0.031 12.9 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family NmrA PF05368.8 EGC37410.1 - 0.024 13.9 0.0 0.07 12.3 0.0 1.7 2 0 0 2 2 2 0 NmrA-like family OTU PF02338.14 EGC37411.1 - 3.2e-15 56.7 0.4 6.8e-15 55.7 0.1 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC37412.1 - 2.2 6.4 14.4 2.1 6.5 10.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 ketoacyl-synt PF00109.21 EGC37413.1 - 2.8e-47 161.3 0.0 6.1e-47 160.2 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC37413.1 - 8.7e-44 150.1 0.0 1.5e-43 149.3 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain KR PF08659.5 EGC37413.1 - 1.5e-22 80.1 0.0 3.1e-22 79.1 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC37413.1 - 2.4e-21 76.0 0.0 2.4e-21 76.0 0.0 3.7 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.1 EGC37413.1 - 1.5e-18 66.9 0.0 2.4e-18 66.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC37413.1 - 2.9e-14 53.3 0.0 5.1e-14 52.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Ketoacyl-synt_C PF02801.17 EGC37413.1 - 5.9e-14 51.9 0.0 2.7e-13 49.8 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain ADH_zinc_N_2 PF13602.1 EGC37413.1 - 3.3e-08 34.4 0.0 7.2e-08 33.3 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC37413.1 - 1.7e-07 31.1 0.0 3.9e-07 29.9 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC37413.1 - 2.3e-07 31.1 0.0 1.4e-06 28.6 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain ADH_N PF08240.7 EGC37413.1 - 3.6e-07 29.9 0.1 8.1e-07 28.7 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PP-binding PF00550.20 EGC37413.1 - 3.9e-06 27.0 0.2 1.5e-05 25.1 0.1 2.1 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_18 PF12847.2 EGC37413.1 - 7.4e-06 26.5 0.0 3.7e-05 24.2 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC37413.1 - 7.4e-06 25.1 0.1 1.4e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_25 PF13649.1 EGC37413.1 - 0.057 13.7 0.0 1.4 9.2 0.0 2.7 2 0 0 2 2 2 0 Methyltransferase domain FNIP PF05725.7 EGC37414.1 - 1e-17 63.7 90.0 1.1e-07 31.6 1.0 12.6 6 3 3 10 10 10 8 FNIP Repeat DUF1769 PF08588.5 EGC37414.1 - 0.00052 19.9 0.1 0.19 11.6 0.1 3.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1769) RGS PF00615.14 EGC37415.1 - 1.2e-24 86.6 10.9 1.5e-24 86.3 7.6 1.1 1 0 0 1 1 1 1 Regulator of G protein signaling domain DUF1977 PF09320.6 EGC37415.1 - 0.62 10.3 5.3 4.8 7.4 3.5 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1977) RCC1 PF00415.13 EGC37416.1 - 4.5e-59 196.4 10.8 2.4e-11 43.6 0.0 9.5 8 2 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC37416.1 - 2e-46 154.6 27.6 1.6e-08 33.9 2.0 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RabGAP-TBC PF00566.13 EGC37416.1 - 3.8e-45 153.9 3.3 3.8e-45 153.9 2.3 2.4 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Exo_endo_phos PF03372.18 EGC37417.1 - 0.007 16.3 0.0 0.0091 15.9 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family WD40 PF00400.27 EGC37419.1 - 5.8e-24 83.0 5.5 1.4e-05 24.7 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC37419.1 - 6.8e-05 22.6 0.5 0.41 10.4 0.0 2.9 1 1 1 2 2 2 2 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 EGC37419.1 - 0.00029 19.2 0.4 0.44 8.7 0.1 2.3 2 0 0 2 2 2 2 Cytochrome D1 heme domain eIF2A PF08662.6 EGC37419.1 - 0.003 17.3 0.1 1.8 8.2 0.0 3.0 1 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A PQQ_3 PF13570.1 EGC37419.1 - 0.0047 17.1 0.1 14 6.0 0.0 3.7 5 0 0 5 5 4 0 PQQ-like domain PQQ PF01011.16 EGC37419.1 - 0.028 13.9 0.0 0.84 9.2 0.0 2.6 2 0 0 2 2 2 0 PQQ enzyme repeat DUF2415 PF10313.4 EGC37419.1 - 0.049 13.3 0.1 2.4 7.9 0.0 2.6 2 0 0 2 2 2 0 Uncharacterised protein domain (DUF2415) DUF3312 PF11768.3 EGC37419.1 - 0.071 11.3 0.1 2.2 6.3 0.1 2.2 1 1 0 2 2 2 0 Protein of unknown function (DUF3312) YmzC PF14157.1 EGC37419.1 - 0.072 12.9 8.8 0.29 11.0 0.0 4.7 5 0 0 5 5 5 0 YmzC-like protein Nop14 PF04147.7 EGC37419.1 - 0.17 9.8 27.1 0.22 9.3 18.8 1.1 1 0 0 1 1 1 0 Nop14-like family Nop53 PF07767.6 EGC37419.1 - 0.64 8.9 16.9 0.87 8.5 11.7 1.2 1 0 0 1 1 1 0 Nop53 (60S ribosomal biogenesis) YL1 PF05764.8 EGC37419.1 - 1.2 8.7 27.3 2.4 7.7 18.9 1.4 1 0 0 1 1 1 0 YL1 nuclear protein CENP-T PF15511.1 EGC37419.1 - 1.2 8.2 16.4 1.8 7.7 11.4 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CDC45 PF02724.9 EGC37419.1 - 2 6.3 22.4 3 5.7 15.5 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF1510 PF07423.6 EGC37419.1 - 8.4 5.6 22.6 14 4.9 15.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nol1_Nop2_Fmu PF01189.12 EGC37420.1 - 4.6e-37 127.9 0.0 2.2e-22 79.7 0.0 4.1 1 1 1 3 3 3 3 NOL1/NOP2/sun family FtsJ PF01728.14 EGC37420.1 - 0.0043 17.0 0.0 0.0079 16.2 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase SSP160 PF06933.6 EGC37420.1 - 2 6.3 10.1 2.9 5.7 7.0 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pinin_SDK_memA PF04696.8 EGC37421.1 - 6.8e-29 100.1 20.0 6.8e-29 100.1 13.9 3.5 2 2 0 3 3 3 1 pinin/SDK/memA/ protein conserved region Glyco_hydro_18 PF00704.23 EGC37422.1 - 1.5e-43 149.5 0.7 2e-43 149.1 0.5 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 adh_short PF00106.20 EGC37425.1 - 6.5e-21 74.9 0.0 8e-21 74.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC37425.1 - 7.7e-16 58.5 0.0 1e-15 58.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC37425.1 - 2.4e-05 24.0 0.0 3.2e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC37425.1 - 0.0008 18.6 0.0 0.0013 17.9 0.0 1.5 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC37425.1 - 0.011 15.1 0.0 0.019 14.3 0.0 1.3 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC37425.1 - 0.14 12.1 0.0 0.19 11.7 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Streptin-Immun PF11083.3 EGC37425.1 - 0.92 9.5 4.4 3 7.8 0.1 2.9 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein adh_short PF00106.20 EGC37426.1 - 1.2e-20 74.0 0.0 1.6e-20 73.6 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC37426.1 - 4.3e-14 52.8 0.0 5.5e-14 52.5 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC37426.1 - 0.0054 16.4 0.0 0.0085 15.7 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC37426.1 - 0.05 13.5 0.0 0.09 12.7 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding Pkinase PF00069.20 EGC37427.1 - 6.7e-58 195.8 0.6 9.3e-58 195.3 0.4 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37427.1 - 1.5e-25 89.8 0.3 8e-24 84.1 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Choline_kinase PF01633.15 EGC37427.1 - 0.0072 15.9 1.3 0.015 14.8 0.9 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase APH PF01636.18 EGC37427.1 - 0.03 14.0 0.0 0.051 13.2 0.0 1.3 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF1196 PF06709.6 EGC37427.1 - 0.04 13.8 0.7 0.087 12.7 0.5 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1196) ABC1 PF03109.11 EGC37427.1 - 0.056 13.4 0.0 0.15 12.0 0.0 1.8 1 0 0 1 1 1 0 ABC1 family YrbL-PhoP_reg PF10707.4 EGC37427.1 - 0.18 11.1 4.4 0.41 9.9 0.2 2.2 1 1 1 2 2 2 0 PhoP regulatory network protein YrbL CDC27 PF09507.5 EGC37428.1 - 1.5e-19 70.5 45.3 1.5e-19 70.5 31.4 4.2 1 1 3 4 4 4 2 DNA polymerase subunit Cdc27 MOZ_SAS PF01853.13 EGC37429.1 - 2.5e-71 238.8 1.1 5.6e-70 234.4 0.8 2.3 1 1 0 1 1 1 1 MOZ/SAS family Tudor-knot PF11717.3 EGC37429.1 - 3.9e-20 71.2 3.2 1.1e-19 69.8 2.2 1.9 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain MIP-T3 PF10243.4 EGC37429.1 - 0.0068 14.9 50.2 0.01 14.3 34.8 1.2 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 RRM_1 PF00076.17 EGC37430.1 - 8.7e-17 60.5 0.0 1.2e-16 60.1 0.0 1.2 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37430.1 - 6.3e-15 54.9 0.0 8e-15 54.5 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37430.1 - 1.9e-10 40.4 0.0 2.9e-10 39.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC37430.1 - 0.018 14.7 0.0 0.035 13.8 0.0 1.5 2 0 0 2 2 2 0 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGC37430.1 - 0.047 13.5 0.0 0.062 13.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding motif Abhydrolase_2 PF02230.11 EGC37431.1 - 0.076 12.4 1.0 0.27 10.6 0.2 2.0 2 0 0 2 2 2 0 Phospholipase/Carboxylesterase Cob_adeno_trans PF01923.13 EGC37431.1 - 0.13 12.0 2.2 0.39 10.4 1.5 1.8 1 1 0 1 1 1 0 Cobalamin adenosyltransferase Ank_5 PF13857.1 EGC37432.1 - 0.0099 16.1 3.9 21 5.5 1.5 4.3 2 1 1 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC37432.1 - 0.031 14.7 1.2 0.28 11.7 0.6 2.9 2 0 0 2 2 2 0 Ankyrin repeats (many copies) UPF0051 PF01458.12 EGC37433.1 - 0.066 12.6 0.0 0.082 12.3 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) Erg28 PF03694.8 EGC37434.1 - 3.6e-33 113.8 0.7 4.1e-33 113.6 0.5 1.0 1 0 0 1 1 1 1 Erg28 like protein TLD PF07534.11 EGC37435.1 - 1e-31 109.7 0.2 1.6e-31 109.1 0.2 1.3 1 0 0 1 1 1 1 TLD Coiled PF05710.7 EGC37437.1 - 0.091 13.2 0.2 0.1 13.0 0.2 1.3 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC37438.1 - 0.0004 20.7 2.5 0.00041 20.7 1.7 1.1 1 0 0 1 1 1 1 Coiled coil FIBP PF05427.6 EGC37439.1 - 7.5e-70 235.9 4.9 5.9e-57 193.5 2.1 2.0 2 0 0 2 2 2 2 Acidic fibroblast growth factor binding (FIBP) zf-TRAF PF02176.13 EGC37440.1 - 1.5e-06 28.4 9.8 1.5e-06 28.4 6.8 4.6 4 1 0 4 4 4 2 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 EGC37440.1 - 3.3e-05 23.4 7.1 3.3e-05 23.4 4.9 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37440.1 - 0.0057 16.6 8.5 0.0057 16.6 5.9 3.3 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) MitMem_reg PF13012.1 EGC37440.1 - 0.075 13.1 1.4 0.12 12.4 0.3 1.9 2 0 0 2 2 2 0 Maintenance of mitochondrial structure and function Fzo_mitofusin PF04799.8 EGC37440.1 - 0.32 10.3 3.2 0.55 9.5 1.2 2.1 2 1 0 2 2 2 0 fzo-like conserved region zf-C3HC4_3 PF13920.1 EGC37441.1 - 1.5e-06 27.7 12.2 1.5e-06 27.7 8.5 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_4 PF14570.1 EGC37441.1 - 5.1e-05 22.7 11.9 5.1e-05 22.7 8.3 3.1 2 1 1 3 3 3 1 RING/Ubox like zinc-binding domain zf-C3HC4_2 PF13923.1 EGC37441.1 - 5.5e-05 23.1 13.8 5.5e-05 23.1 9.6 3.3 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC37441.1 - 0.00026 20.7 12.1 0.00026 20.7 8.4 3.2 2 1 0 2 2 2 1 Ring finger domain TAF8_C PF10406.4 EGC37441.1 - 0.0082 16.1 0.1 0.018 15.0 0.0 1.5 1 0 0 1 1 1 1 Transcription factor TFIID complex subunit 8 C-term DZR PF12773.2 EGC37441.1 - 0.019 14.8 0.6 0.019 14.8 0.4 3.5 3 1 0 3 3 3 0 Double zinc ribbon Kinesin-relat_1 PF12711.2 EGC37441.1 - 0.029 14.7 0.8 0.089 13.2 0.1 2.1 2 0 0 2 2 2 0 Kinesin motor PUB PF09409.5 EGC37441.1 - 0.12 12.1 2.7 0.88 9.3 0.2 2.9 3 0 0 3 3 3 0 PUB domain DUF2205 PF10224.4 EGC37441.1 - 0.25 10.9 3.2 1.7 8.2 0.1 3.0 2 1 1 3 3 3 0 Predicted coiled-coil protein (DUF2205) RabGAP-TBC PF00566.13 EGC37442.1 - 3e-30 105.2 5.3 3e-30 105.2 3.7 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF692 PF05114.8 EGC37442.1 - 0.079 11.8 0.1 0.12 11.2 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF692) RasGAP PF00616.14 EGC37443.1 - 2.4e-42 144.8 0.0 2.4e-42 144.8 0.0 3.4 3 1 0 3 3 3 1 GTPase-activator protein for Ras-like GTPase CENP-H PF05837.7 EGC37443.1 - 0.85 9.8 13.7 1.2 9.3 1.1 3.8 4 0 0 4 4 4 0 Centromere protein H (CENP-H) EF-hand_2 PF09068.6 EGC37443.1 - 5.1 7.1 9.8 0.8 9.7 3.0 2.5 2 1 1 3 3 3 0 EF hand Rap_GAP PF02145.10 EGC37444.1 - 1.5e-37 128.7 7.3 1.5e-37 128.7 5.1 2.5 2 0 0 2 2 2 1 Rap/ran-GAP SulA PF03846.9 EGC37446.1 - 0.00018 21.1 0.3 0.0013 18.4 0.0 2.1 2 0 0 2 2 2 1 Cell division inhibitor SulA Ribosomal_L4 PF00573.17 EGC37447.1 - 4e-53 179.6 1.3 4.9e-53 179.3 0.9 1.1 1 0 0 1 1 1 1 Ribosomal protein L4/L1 family Ribosomal_L6 PF00347.18 EGC37449.1 - 8.4e-26 90.2 1.3 7.6e-15 55.1 0.2 2.1 2 0 0 2 2 2 2 Ribosomal protein L6 Pyridox_oxase_2 PF12766.2 EGC37449.1 - 0.072 13.4 0.0 0.12 12.6 0.0 1.4 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase zf-CCHC PF00098.18 EGC37450.1 - 1.2e-05 24.9 3.9 3.1e-05 23.6 2.7 1.8 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_3 PF13917.1 EGC37450.1 - 0.064 12.9 1.3 0.17 11.6 0.9 1.7 1 0 0 1 1 1 0 Zinc knuckle DUF1421 PF07223.6 EGC37451.1 - 1.3 8.6 42.0 1.8 8.2 29.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1421) SKI PF01202.17 EGC37452.1 - 1.1e-16 61.1 0.0 1.4e-16 60.7 0.0 1.2 1 0 0 1 1 1 1 Shikimate kinase AAA_18 PF13238.1 EGC37452.1 - 1.1e-09 38.6 0.2 2.9e-09 37.3 0.1 1.7 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC37452.1 - 1.8e-08 35.2 0.0 2.3e-08 34.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC37452.1 - 1.9e-07 31.0 0.0 2.8e-07 30.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EGC37452.1 - 1.3e-05 25.1 0.0 3.8e-05 23.6 0.0 1.8 1 1 0 1 1 1 1 Cytidylate kinase-like family APS_kinase PF01583.15 EGC37452.1 - 0.00053 19.6 0.0 0.00072 19.2 0.0 1.2 1 0 0 1 1 1 1 Adenylylsulphate kinase Thymidylate_kin PF02223.12 EGC37452.1 - 0.0054 16.1 0.5 0.32 10.3 0.0 2.2 2 0 0 2 2 2 1 Thymidylate kinase Arch_ATPase PF01637.13 EGC37452.1 - 0.0074 16.0 0.2 0.017 14.8 0.1 1.8 1 1 0 1 1 1 1 Archaeal ATPase G-alpha PF00503.15 EGC37452.1 - 0.0089 14.7 0.5 0.012 14.3 0.3 1.2 1 0 0 1 1 1 1 G-protein alpha subunit AAA_22 PF13401.1 EGC37452.1 - 0.01 15.9 1.0 0.016 15.3 0.2 1.9 2 1 0 2 2 2 0 AAA domain AAA PF00004.24 EGC37452.1 - 0.01 15.9 0.6 0.017 15.2 0.4 1.8 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) 6PF2K PF01591.13 EGC37452.1 - 0.012 14.7 1.1 0.02 13.9 0.1 2.1 2 1 0 2 2 2 0 6-phosphofructo-2-kinase NACHT PF05729.7 EGC37452.1 - 0.018 14.6 0.0 0.047 13.3 0.0 1.7 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EGC37452.1 - 0.023 14.7 0.1 0.087 12.7 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain CM_2 PF01817.16 EGC37452.1 - 0.023 14.7 0.1 0.33 11.0 0.0 2.7 2 1 0 2 2 2 0 Chorismate mutase type II DUF2075 PF09848.4 EGC37452.1 - 0.027 13.4 0.0 0.036 13.0 0.0 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2075) UPF0079 PF02367.12 EGC37452.1 - 0.031 13.9 0.0 0.058 13.0 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EGC37452.1 - 0.035 13.6 0.0 0.045 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC37452.1 - 0.036 14.3 1.6 0.041 14.1 1.0 1.3 1 1 0 1 1 1 0 ABC transporter AAA_14 PF13173.1 EGC37452.1 - 0.04 13.8 0.4 0.12 12.2 0.1 2.1 1 1 1 2 2 2 0 AAA domain NB-ARC PF00931.17 EGC37452.1 - 0.041 12.7 0.1 0.073 11.9 0.1 1.3 1 0 0 1 1 1 0 NB-ARC domain AAA_28 PF13521.1 EGC37452.1 - 0.042 13.8 0.0 0.064 13.2 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGC37452.1 - 0.054 13.0 0.1 0.11 12.0 0.1 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain T2SE PF00437.15 EGC37452.1 - 0.057 12.3 0.0 0.12 11.2 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein CPT PF07931.7 EGC37452.1 - 0.075 12.6 0.0 0.1 12.2 0.0 1.4 1 1 0 1 1 1 0 Chloramphenicol phosphotransferase-like protein SRP54 PF00448.17 EGC37452.1 - 0.14 11.6 0.0 0.2 11.0 0.0 1.3 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Gtr1_RagA PF04670.7 EGC37452.1 - 0.37 9.8 2.8 0.75 8.8 1.2 2.0 1 1 1 2 2 2 0 Gtr1/RagA G protein conserved region AAA_23 PF13476.1 EGC37452.1 - 3.6 7.8 11.0 22 5.3 7.7 2.0 1 1 0 1 1 1 0 AAA domain PBP PF01161.15 EGC37453.1 - 6.9e-29 100.5 0.1 8.7e-29 100.2 0.1 1.1 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein HR1 PF02185.11 EGC37454.1 - 2.3 7.9 6.6 0.6 9.8 2.2 1.8 2 0 0 2 2 2 0 Hr1 repeat DIOX_N PF14226.1 EGC37455.1 - 3.4e-29 101.7 0.0 5e-29 101.1 0.0 1.3 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC37455.1 - 1.1e-23 83.3 0.0 1.9e-23 82.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily G-alpha PF00503.15 EGC37456.1 - 1.2e-128 429.1 6.3 1.4e-128 428.8 4.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC37456.1 - 1.8e-15 56.6 1.6 7e-12 44.9 0.1 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Miro PF08477.8 EGC37456.1 - 0.00076 19.9 1.5 0.17 12.3 0.1 3.1 2 1 1 3 3 3 1 Miro-like protein Gtr1_RagA PF04670.7 EGC37456.1 - 0.0018 17.4 5.7 0.089 11.9 0.3 2.8 2 2 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC37456.1 - 0.0039 17.1 0.7 0.16 11.9 0.5 2.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase UPF0113 PF03657.8 EGC37456.1 - 0.033 13.8 0.3 0.11 12.2 0.0 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0113) THDPS_N PF14790.1 EGC37456.1 - 0.1 12.2 0.9 0.58 9.7 0.0 2.2 2 0 0 2 2 2 0 Tetrahydrodipicolinate N-succinyltransferase N-terminal AAA_29 PF13555.1 EGC37456.1 - 0.12 11.9 0.0 0.24 10.9 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain Hyccin PF09790.4 EGC37457.1 - 3.3e-29 101.7 4.7 4.3e-29 101.3 3.3 1.2 1 0 0 1 1 1 1 Hyccin L51_S25_CI-B8 PF05047.11 EGC37460.1 - 2.6e-06 27.0 0.0 6e-06 25.8 0.0 1.7 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain Asparaginase_2 PF01112.13 EGC37461.1 - 4e-29 101.3 0.1 1.7e-19 69.7 0.0 2.6 2 1 0 2 2 2 2 Asparaginase Mito_carr PF00153.22 EGC37462.1 - 9.2e-76 249.6 0.2 5.5e-26 90.1 0.0 3.5 3 0 0 3 3 3 3 Mitochondrial carrier protein EF-hand_7 PF13499.1 EGC37462.1 - 9.5e-25 86.5 6.4 3.3e-05 23.9 0.1 4.8 5 0 0 5 5 5 4 EF-hand domain pair EF-hand_1 PF00036.27 EGC37462.1 - 3.7e-21 72.7 16.0 1.2e-06 27.3 0.1 6.0 7 0 0 7 7 7 4 EF hand EF-hand_8 PF13833.1 EGC37462.1 - 1.8e-20 72.2 9.6 8.6e-07 28.4 0.4 4.4 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC37462.1 - 4.4e-19 66.5 16.9 1.1e-05 24.8 0.2 6.8 6 0 0 6 6 6 4 EF-hand domain EF-hand_5 PF13202.1 EGC37462.1 - 1.1e-14 52.9 7.6 0.0003 19.9 0.1 4.1 4 0 0 4 4 4 3 EF hand EF-hand_4 PF12763.2 EGC37462.1 - 0.00058 19.5 3.3 0.045 13.4 0.1 3.2 3 0 0 3 3 3 1 Cytoskeletal-regulatory complex EF hand EF-hand_9 PF14658.1 EGC37462.1 - 0.011 15.6 0.4 28 4.7 0.0 3.9 3 1 0 3 3 3 0 EF-hand domain Cytochrom_B561 PF03188.11 EGC37463.1 - 2.8e-14 53.1 11.1 5.7e-14 52.1 7.7 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DOMON PF03351.12 EGC37463.1 - 5.1e-13 49.0 0.5 8.8e-13 48.2 0.3 1.4 1 0 0 1 1 1 1 DOMON domain DUF2427 PF10348.4 EGC37463.1 - 0.0042 16.6 12.6 0.078 12.5 5.1 3.2 1 1 2 3 3 3 2 Domain of unknown function (DUF2427) Ni_hydr_CYTB PF01292.15 EGC37463.1 - 1.9 7.8 13.3 61 2.9 9.2 2.6 1 1 0 1 1 1 0 Prokaryotic cytochrome b561 EGF_2 PF07974.8 EGC37465.1 - 2.4e-07 30.7 27.2 0.0022 18.1 6.7 2.6 2 0 0 2 2 2 2 EGF-like domain DUF1870 PF08965.5 EGC37465.1 - 0.00014 21.4 0.2 1.4 8.6 0.0 3.5 2 0 0 2 2 2 2 Domain of unknown function (DUF1870) EGF_2 PF07974.8 EGC37466.1 - 0.00056 20.0 9.6 0.0012 18.9 6.7 1.5 1 0 0 1 1 1 1 EGF-like domain MSC PF09402.5 EGC37466.1 - 0.0064 15.2 0.3 0.012 14.3 0.2 1.4 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Syndecan PF01034.15 EGC37466.1 - 0.084 12.5 0.6 0.17 11.5 0.4 1.4 1 0 0 1 1 1 0 Syndecan domain EGF_2 PF07974.8 EGC37467.1 - 0.00048 20.2 9.6 0.00099 19.2 6.7 1.5 1 0 0 1 1 1 1 EGF-like domain MSC PF09402.5 EGC37467.1 - 0.0059 15.3 0.2 0.011 14.5 0.1 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Syndecan PF01034.15 EGC37467.1 - 0.078 12.6 0.8 0.16 11.6 0.5 1.4 1 0 0 1 1 1 0 Syndecan domain CBS PF00571.23 EGC37469.1 - 1.7e-27 94.9 2.4 1.7e-15 56.4 0.1 2.3 2 0 0 2 2 2 2 CBS domain PRC PF05239.11 EGC37469.1 - 0.0031 17.3 1.5 0.073 12.9 0.0 2.8 3 0 0 3 3 3 1 PRC-barrel domain Kinesin PF00225.18 EGC37470.1 - 4.6e-102 341.1 0.4 5.6e-58 196.2 0.0 4.3 3 1 0 3 3 3 2 Kinesin motor domain WD40 PF00400.27 EGC37470.1 - 4.7e-36 121.3 19.7 6.7e-05 22.6 0.1 8.3 8 0 0 8 8 8 7 WD domain, G-beta repeat AAA PF00004.24 EGC37471.1 - 3.3e-43 147.0 0.0 7.1e-43 145.9 0.0 1.6 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC37471.1 - 2.6e-07 30.7 0.0 5.5e-06 26.4 0.0 2.3 1 1 1 2 2 2 1 AAA ATPase domain AAA_5 PF07728.9 EGC37471.1 - 2.9e-07 30.2 0.2 4.6e-06 26.4 0.1 2.6 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC37471.1 - 2.1e-06 27.9 0.2 0.00057 20.0 0.0 2.9 2 1 0 2 2 2 1 AAA domain RuvB_N PF05496.7 EGC37471.1 - 2.3e-06 26.8 0.0 4.7e-06 25.8 0.0 1.5 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGC37471.1 - 1.6e-05 24.9 0.0 3.9e-05 23.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) AAA_18 PF13238.1 EGC37471.1 - 0.00019 21.7 0.5 0.0028 17.9 0.0 2.5 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC37471.1 - 0.0002 22.1 0.5 0.00071 20.3 0.1 2.3 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC37471.1 - 0.00024 20.7 0.0 0.00053 19.6 0.0 1.6 1 0 0 1 1 1 1 Part of AAA domain RNA_helicase PF00910.17 EGC37471.1 - 0.0003 20.9 0.0 0.002 18.2 0.0 2.3 2 0 0 2 2 2 1 RNA helicase IstB_IS21 PF01695.12 EGC37471.1 - 0.00077 18.9 0.0 0.0017 17.8 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_14 PF13173.1 EGC37471.1 - 0.00089 19.1 0.1 0.0022 17.8 0.0 1.7 2 0 0 2 2 1 1 AAA domain TIP49 PF06068.8 EGC37471.1 - 0.0016 17.2 0.0 0.0032 16.2 0.0 1.4 1 0 0 1 1 1 1 TIP49 C-terminus DUF815 PF05673.8 EGC37471.1 - 0.0023 16.9 0.0 0.0041 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) ResIII PF04851.10 EGC37471.1 - 0.0026 17.6 0.1 0.048 13.4 0.0 2.3 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Mg_chelatase PF01078.16 EGC37471.1 - 0.0028 16.8 0.0 0.0056 15.8 0.0 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI Arch_ATPase PF01637.13 EGC37471.1 - 0.0031 17.2 0.2 0.038 13.6 0.0 2.4 2 1 0 2 2 2 1 Archaeal ATPase AAA_33 PF13671.1 EGC37471.1 - 0.0036 17.1 0.0 0.0071 16.2 0.0 1.5 1 0 0 1 1 1 1 AAA domain Sigma54_activat PF00158.21 EGC37471.1 - 0.0053 16.2 0.0 0.02 14.3 0.0 2.0 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_25 PF13481.1 EGC37471.1 - 0.0063 15.9 0.1 0.026 13.9 0.1 2.0 1 1 1 2 2 2 1 AAA domain Zeta_toxin PF06414.7 EGC37471.1 - 0.0098 15.0 0.6 0.026 13.6 0.0 1.8 2 0 0 2 2 2 1 Zeta toxin Parvo_NS1 PF01057.12 EGC37471.1 - 0.01 14.6 0.0 0.023 13.5 0.0 1.5 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 AAA_3 PF07726.6 EGC37471.1 - 0.011 15.3 0.0 0.023 14.2 0.0 1.5 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGC37471.1 - 0.011 15.3 0.0 0.032 13.9 0.0 1.9 1 1 0 1 1 1 0 NACHT domain UPF0079 PF02367.12 EGC37471.1 - 0.013 15.0 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 Sigma54_activ_2 PF14532.1 EGC37471.1 - 0.018 15.1 0.0 0.065 13.2 0.0 2.0 1 1 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGC37471.1 - 0.021 14.3 0.9 0.041 13.4 0.0 1.8 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGC37471.1 - 0.027 14.4 0.0 0.049 13.5 0.0 1.4 1 0 0 1 1 1 0 AAA domain KaiC PF06745.8 EGC37471.1 - 0.032 13.3 0.1 0.12 11.4 0.0 2.0 3 0 0 3 3 3 0 KaiC PhoH PF02562.11 EGC37471.1 - 0.034 13.3 0.0 0.068 12.3 0.0 1.4 1 0 0 1 1 1 0 PhoH-like protein AAA_11 PF13086.1 EGC37471.1 - 0.035 13.6 1.5 0.25 10.8 0.0 2.4 2 1 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGC37471.1 - 0.052 13.1 0.0 0.097 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC37471.1 - 0.053 13.8 0.0 0.13 12.5 0.0 1.7 1 0 0 1 1 1 0 ABC transporter AAA_23 PF13476.1 EGC37471.1 - 3.9 7.7 0.0 3.9 7.7 0.0 2.3 2 0 0 2 2 1 0 AAA domain Transferase PF02458.10 EGC37472.1 - 4.2e-11 41.9 0.0 7.5e-11 41.1 0.0 1.3 1 1 0 1 1 1 1 Transferase family Transferase PF02458.10 EGC37473.1 - 3.7e-08 32.2 0.0 1.8e-07 29.9 0.0 1.8 1 1 0 1 1 1 1 Transferase family DAGK_cat PF00781.19 EGC37474.1 - 1.1e-21 76.6 0.0 2.1e-21 75.7 0.0 1.5 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain PLDc_2 PF13091.1 EGC37474.1 - 0.0013 18.4 0.2 0.0046 16.7 0.0 2.0 2 0 0 2 2 2 1 PLD-like domain DUF59 PF01883.14 EGC37475.1 - 9.1e-11 41.5 0.0 1.2e-10 41.1 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function DUF59 Ribosomal_S4 PF00163.14 EGC37476.1 - 2.3e-27 95.2 0.4 2.3e-27 95.2 0.3 1.8 2 1 1 3 3 3 1 Ribosomal protein S4/S9 N-terminal domain S4 PF01479.20 EGC37476.1 - 2.2e-11 42.9 0.9 8.1e-11 41.1 0.6 2.0 1 0 0 1 1 1 1 S4 domain Thioredoxin PF00085.15 EGC37477.1 - 3.9e-31 106.8 0.0 1.9e-14 53.1 0.0 3.9 4 0 0 4 4 4 2 Thioredoxin Thioredoxin_6 PF13848.1 EGC37477.1 - 2.8e-18 66.3 10.9 4.2e-18 65.8 2.5 3.4 2 1 0 3 3 3 1 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGC37477.1 - 2.2e-08 34.2 7.7 0.0099 16.0 1.9 5.8 5 2 0 5 5 5 3 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGC37477.1 - 1.1e-05 25.3 0.0 0.12 12.3 0.0 2.7 2 0 0 2 2 2 2 Thioredoxin-like DUF167 PF02594.11 EGC37478.1 - 4.2e-23 81.0 1.4 5.6e-23 80.6 1.0 1.1 1 0 0 1 1 1 1 Uncharacterised ACR, YggU family COG1872 APG6 PF04111.7 EGC37479.1 - 0.0028 16.7 3.1 0.0047 16.0 2.1 1.3 1 0 0 1 1 1 1 Autophagy protein Apg6 eRF1_3 PF03465.10 EGC37479.1 - 0.036 14.3 0.1 0.55 10.5 0.0 2.4 1 1 1 2 2 2 0 eRF1 domain 3 YjcZ PF13990.1 EGC37479.1 - 0.05 12.7 0.3 0.083 12.0 0.2 1.5 1 0 0 1 1 1 0 YjcZ-like protein DUF2203 PF09969.4 EGC37479.1 - 0.1 12.8 0.7 8.1 6.6 0.1 2.8 2 2 0 2 2 2 0 Uncharacterized conserved protein (DUF2203) DUF1664 PF07889.7 EGC37479.1 - 0.33 10.7 2.4 1.8 8.3 0.2 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) DUF3439 PF11921.3 EGC37479.1 - 0.88 9.3 11.4 1.8 8.3 7.4 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) Tropomyosin_1 PF12718.2 EGC37479.1 - 1.6 8.6 7.9 0.12 12.1 1.0 2.2 2 1 0 2 2 2 0 Tropomyosin like DUF2718 PF10918.3 EGC37479.1 - 2.6 8.0 6.9 0.35 10.9 0.5 2.5 1 1 2 3 3 3 0 Protein of unknown function (DUF2718) C2 PF00168.25 EGC37480.1 - 7.7e-13 48.1 0.1 9.4e-08 31.8 0.0 3.0 2 0 0 2 2 2 2 C2 domain GRAM PF02893.15 EGC37480.1 - 3.3e-12 45.7 0.8 9.8e-08 31.4 0.0 3.4 3 0 0 3 3 3 2 GRAM domain Membr_traf_MHD PF10540.4 EGC37480.1 - 3.3e-05 23.6 0.1 0.00022 21.0 0.1 2.6 1 1 0 1 1 1 1 Munc13 (mammalian uncoordinated) homology domain Nramp PF01566.13 EGC37481.1 - 1.2e-131 438.7 23.7 1.8e-131 438.2 16.4 1.2 1 0 0 1 1 1 1 Natural resistance-associated macrophage protein Caveolin PF01146.12 EGC37481.1 - 0.43 10.1 4.5 4.4 6.8 1.4 2.9 2 0 0 2 2 2 0 Caveolin PPR PF01535.15 EGC37482.1 - 0.087 12.8 0.9 14 5.9 0.0 3.2 3 0 0 3 3 3 0 PPR repeat DUF937 PF06078.6 EGC37483.1 - 0.023 14.9 0.5 0.023 14.9 0.4 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF937) Coiled PF05710.7 EGC37483.1 - 1.8 9.1 13.6 2.2 8.8 9.4 1.3 1 1 0 1 1 1 0 Coiled coil ATP-synt_C PF00137.16 EGC37484.1 - 2.2e-32 110.7 28.4 9.3e-17 60.7 5.7 2.1 2 0 0 2 2 2 2 ATP synthase subunit C Cyt_c_ox_IV PF12270.3 EGC37484.1 - 1.3 8.8 10.2 10 5.8 0.0 2.8 3 0 0 3 3 3 0 Cytochrome c oxidase subunit IV Oxidored_q2 PF00420.19 EGC37484.1 - 2.5 7.7 7.3 79 2.9 5.1 2.5 1 1 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L RhoGAP PF00620.22 EGC37485.1 - 1.9e-35 121.6 0.4 6.8e-35 119.9 0.3 1.9 1 0 0 1 1 1 1 RhoGAP domain F-box-like PF12937.2 EGC37485.1 - 1.2e-11 44.0 1.4 3.1e-11 42.8 1.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC37485.1 - 4.1e-08 32.6 0.4 1.2e-07 31.2 0.3 1.9 1 0 0 1 1 1 1 F-box domain Mcp5_PH PF12814.2 EGC37485.1 - 0.00066 19.5 1.0 0.002 18.0 0.7 1.9 1 0 0 1 1 1 1 Meiotic cell cortex C-terminal pleckstrin homology PH_11 PF15413.1 EGC37485.1 - 0.019 15.1 0.3 0.019 15.1 0.2 3.9 4 1 0 4 4 4 0 Pleckstrin homology domain DnaJ PF00226.26 EGC37486.1 - 2.9e-12 46.1 0.9 5.9e-12 45.1 0.6 1.5 1 0 0 1 1 1 1 DnaJ domain RRN3 PF05327.6 EGC37486.1 - 0.027 12.6 0.2 0.036 12.1 0.2 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 Cathelicidins PF00666.12 EGC37486.1 - 0.037 14.1 0.6 0.7 10.0 0.0 2.2 2 0 0 2 2 2 0 Cathelicidin OTU PF02338.14 EGC37487.1 - 5.8e-13 49.4 0.1 5.8e-13 49.4 0.1 1.9 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGC37487.1 - 0.017 14.4 4.5 0.2 10.9 0.0 2.9 2 1 1 3 3 3 0 Peptidase C65 Otubain BRF1 PF07741.8 EGC37487.1 - 0.075 13.2 2.8 0.16 12.1 2.0 1.6 1 0 0 1 1 1 0 Brf1-like TBP-binding domain DUF4220 PF13968.1 EGC37489.1 - 2.1 7.3 4.8 2.3 7.2 3.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4220) Bactofilin PF04519.8 EGC37490.1 - 0.012 15.6 1.2 0.012 15.6 0.8 7.2 6 2 1 7 7 7 0 Polymer-forming cytoskeletal FecR PF04773.8 EGC37490.1 - 0.026 14.7 1.2 1.6 9.0 0.0 4.4 4 1 1 5 5 5 0 FecR protein zf-C2H2_jaz PF12171.3 EGC37491.1 - 7.5e-09 35.4 2.2 1.4e-08 34.6 1.6 1.5 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC37491.1 - 9.5e-08 31.9 1.8 1.6e-07 31.2 1.3 1.4 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-DBF PF07535.7 EGC37491.1 - 0.024 14.3 0.8 0.048 13.3 0.5 1.5 1 0 0 1 1 1 0 DBF zinc finger SPOC PF07744.8 EGC37491.1 - 0.079 13.4 0.3 0.14 12.6 0.2 1.3 1 0 0 1 1 1 0 SPOC domain zf-U1 PF06220.7 EGC37491.1 - 0.14 11.7 0.7 0.26 10.8 0.5 1.4 1 0 0 1 1 1 0 U1 zinc finger zf-C2H2_2 PF12756.2 EGC37491.1 - 0.38 10.8 5.5 0.12 12.5 0.7 2.2 1 1 1 2 2 2 0 C2H2 type zinc-finger (2 copies) Y_phosphatase2 PF03162.8 EGC37492.1 - 1.5e-42 144.7 0.0 1.6e-42 144.6 0.0 1.0 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGC37492.1 - 0.0038 16.5 0.0 0.0056 16.0 0.0 1.3 1 1 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC37492.1 - 0.022 15.0 0.0 0.068 13.4 0.0 1.6 1 1 1 2 2 2 0 Tyrosine phosphatase family DUF2185 PF09951.4 EGC37493.1 - 1.3e-32 111.3 0.2 3.6e-32 110.0 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF2185) DUF2314 PF10077.4 EGC37493.1 - 0.0013 18.8 0.1 0.13 12.3 0.0 2.2 2 0 0 2 2 2 2 Uncharacterized protein conserved in bacteria (DUF2314) TIP49 PF06068.8 EGC37494.1 - 7.4e-179 594.5 6.3 8.8e-179 594.3 4.4 1.0 1 0 0 1 1 1 1 TIP49 C-terminus AAA PF00004.24 EGC37494.1 - 4.1e-10 39.9 1.5 8.5e-06 26.0 0.1 2.7 2 1 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGC37494.1 - 2.3e-08 33.4 2.2 0.00011 21.3 0.0 3.0 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus DnaB_C PF03796.10 EGC37494.1 - 3.9e-07 29.2 0.1 7.3e-07 28.3 0.1 1.4 1 0 0 1 1 1 1 DnaB-like helicase C terminal domain AAA_22 PF13401.1 EGC37494.1 - 2e-06 27.9 0.4 0.051 13.7 0.0 2.5 1 1 1 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC37494.1 - 5e-06 26.6 0.1 0.0001 22.3 0.0 2.3 1 1 0 1 1 1 1 AAA ATPase domain AAA_5 PF07728.9 EGC37494.1 - 8.1e-06 25.6 0.2 0.015 15.0 0.0 3.2 3 0 0 3 3 3 2 AAA domain (dynein-related subfamily) Sigma54_activat PF00158.21 EGC37494.1 - 3.8e-05 23.2 0.2 0.03 13.7 0.1 2.5 2 0 0 2 2 2 2 Sigma-54 interaction domain Mg_chelatase PF01078.16 EGC37494.1 - 0.00038 19.6 0.8 0.019 14.1 0.2 2.3 2 0 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGC37494.1 - 0.00047 19.6 0.0 0.0014 18.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC37494.1 - 0.0019 17.9 0.4 0.0045 16.7 0.1 1.8 2 0 0 2 2 1 1 Part of AAA domain KaiC PF06745.8 EGC37494.1 - 0.0034 16.5 0.4 0.0068 15.5 0.3 1.5 1 0 0 1 1 1 1 KaiC NACHT PF05729.7 EGC37494.1 - 0.0036 16.9 0.0 0.0073 15.9 0.0 1.5 1 0 0 1 1 1 1 NACHT domain Zeta_toxin PF06414.7 EGC37494.1 - 0.0042 16.2 0.5 0.011 14.8 0.3 1.6 1 0 0 1 1 1 1 Zeta toxin DUF2075 PF09848.4 EGC37494.1 - 0.0056 15.6 0.0 0.01 14.8 0.0 1.4 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) AAA_18 PF13238.1 EGC37494.1 - 0.008 16.4 0.8 0.022 15.0 0.2 2.2 2 1 0 2 2 1 1 AAA domain PIF1 PF05970.9 EGC37494.1 - 0.0083 15.1 1.4 1.1 8.1 0.2 2.2 2 0 0 2 2 2 2 PIF1-like helicase AAA_14 PF13173.1 EGC37494.1 - 0.011 15.5 0.6 2.4 8.0 0.0 3.0 3 0 0 3 3 3 0 AAA domain UPF0079 PF02367.12 EGC37494.1 - 0.03 13.9 0.2 0.1 12.2 0.1 1.9 1 0 0 1 1 1 0 Uncharacterised P-loop hydrolase UPF0079 IstB_IS21 PF01695.12 EGC37494.1 - 0.074 12.4 0.5 0.16 11.3 0.3 1.5 1 0 0 1 1 1 0 IstB-like ATP binding protein AAA_23 PF13476.1 EGC37494.1 - 0.076 13.3 4.3 0.14 12.4 3.0 1.7 1 1 0 1 1 1 0 AAA domain Zot PF05707.7 EGC37494.1 - 0.11 11.9 0.3 8.9 5.7 0.0 2.7 3 0 0 3 3 3 0 Zonular occludens toxin (Zot) PhoH PF02562.11 EGC37494.1 - 0.11 11.6 1.9 0.53 9.4 0.3 2.3 2 0 0 2 2 2 0 PhoH-like protein ResIII PF04851.10 EGC37494.1 - 0.12 12.2 1.2 2.3 8.0 0.1 2.4 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit bPH_4 PF06713.6 EGC37495.1 - 0.15 11.9 2.5 2.2 8.2 0.1 2.7 1 1 0 2 2 2 0 Bacterial PH domain NUC173 PF08161.7 EGC37496.1 - 2.1e-59 200.1 0.1 3.7e-58 196.1 0.0 3.1 3 0 0 3 3 3 1 NUC173 domain zf-LITAF-like PF10601.4 EGC37497.1 - 1.3e-21 76.2 13.2 1.7e-21 75.8 9.1 1.2 1 0 0 1 1 1 1 LITAF-like zinc ribbon domain Claudin_2 PF13903.1 EGC37497.1 - 0.028 14.1 0.0 0.028 14.1 0.0 1.1 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction PyrI_C PF02748.10 EGC37497.1 - 0.051 13.0 0.7 0.051 13.0 0.5 1.9 2 0 0 2 2 2 0 Aspartate carbamoyltransferase regulatory chain, metal binding domain PIG-F PF06699.6 EGC37497.1 - 0.06 13.2 0.1 0.077 12.9 0.1 1.1 1 0 0 1 1 1 0 GPI biosynthesis protein family Pig-F Cytochrome_C7 PF14522.1 EGC37497.1 - 0.075 12.6 2.2 5.8 6.6 0.0 2.2 2 0 0 2 2 2 0 Cytochrome c7 PSCyt3 PF07627.6 EGC37497.1 - 0.17 11.7 0.9 3.5 7.5 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1588) Sgf11 PF08209.6 EGC37497.1 - 0.95 8.8 5.0 4.8 6.5 0.3 2.3 2 0 0 2 2 2 0 Sgf11 (transcriptional regulation protein) zf-H2C2_2 PF13465.1 EGC37497.1 - 1.9 8.9 6.2 19 5.7 0.2 2.6 2 0 0 2 2 2 0 Zinc-finger double domain RecR PF02132.10 EGC37497.1 - 2.8 7.4 6.3 0.64 9.4 0.9 2.1 2 0 0 2 2 2 0 RecR protein Ribosomal_L36 PF00444.13 EGC37498.1 - 4.2e-14 52.2 7.5 5.2e-14 51.9 5.2 1.1 1 0 0 1 1 1 1 Ribosomal protein L36 Flu_PA PF00603.12 EGC37498.1 - 0.025 12.6 0.2 0.025 12.6 0.1 1.0 1 0 0 1 1 1 0 Influenza RNA-dependent RNA polymerase subunit PA S1FA PF04689.8 EGC37499.1 - 0.3 10.9 0.1 0.3 10.9 0.1 1.7 2 0 0 2 2 2 0 DNA binding protein S1FA FAD_binding_4 PF01565.18 EGC37500.1 - 6.2e-20 71.0 0.0 9.9e-20 70.4 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC37500.1 - 2.8e-07 30.3 1.6 6.6e-07 29.1 1.1 1.7 1 0 0 1 1 1 1 Berberine and berberine like DUF3139 PF11337.3 EGC37500.1 - 0.099 12.9 1.7 0.5 10.6 0.1 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) PPR_2 PF13041.1 EGC37502.1 - 3.6e-05 23.6 16.1 0.00051 19.9 0.4 5.9 7 0 0 7 7 7 2 PPR repeat family PPR PF01535.15 EGC37502.1 - 0.032 14.1 9.8 0.051 13.5 0.0 6.0 7 0 0 7 7 7 0 PPR repeat DUF3439 PF11921.3 EGC37503.1 - 0.078 12.7 22.4 0.11 12.2 3.3 3.5 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) FA_hydroxylase PF04116.8 EGC37505.1 - 7.7e-12 45.6 18.2 7.7e-12 45.6 12.6 3.4 3 2 0 3 3 3 1 Fatty acid hydroxylase superfamily FUSC_2 PF13515.1 EGC37505.1 - 0.044 13.7 0.3 0.044 13.7 0.2 3.2 3 1 0 3 3 3 0 Fusaric acid resistance protein-like PBP PF01161.15 EGC37506.1 - 4.6e-23 81.6 0.0 6e-23 81.3 0.0 1.2 1 0 0 1 1 1 1 Phosphatidylethanolamine-binding protein TetR_C_8 PF14278.1 EGC37506.1 - 0.00084 19.6 0.0 0.0021 18.3 0.0 1.7 1 0 0 1 1 1 1 Transcriptional regulator C-terminal region PI3Ka PF00613.15 EGC37507.1 - 2.2e-60 202.9 0.9 5e-60 201.8 0.6 1.5 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC37507.1 - 3.4e-50 170.7 0.1 3.4e-50 170.7 0.1 2.4 2 0 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGC37507.1 - 2.7e-25 88.8 0.0 1.3e-24 86.5 0.0 2.3 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EGC37507.1 - 2.1e-16 59.7 0.3 1.2e-15 57.3 0.1 2.5 2 0 0 2 2 2 1 PI3-kinase family, ras-binding domain ATP-synt_C PF00137.16 EGC37508.1 - 3.7e-24 84.4 34.0 4.9e-14 51.9 6.4 2.1 2 0 0 2 2 2 2 ATP synthase subunit C ATP-synt_C PF00137.16 EGC37509.1 - 4.7e-28 96.8 34.1 1e-16 60.5 7.5 2.0 2 0 0 2 2 2 2 ATP synthase subunit C MecA PF05389.7 EGC37510.1 - 0.016 14.7 0.1 0.023 14.2 0.1 1.2 1 0 0 1 1 1 0 Negative regulator of genetic competence (MecA) DUF4551 PF15087.1 EGC37510.1 - 0.2 10.0 0.9 0.18 10.1 0.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) Fic PF02661.13 EGC37511.1 - 1.7e-20 73.5 0.1 6.9e-20 71.5 0.0 2.0 2 0 0 2 2 2 1 Fic/DOC family Ctf8 PF09696.5 EGC37511.1 - 0.015 15.0 0.2 0.028 14.1 0.1 1.5 1 0 0 1 1 1 0 Ctf8 Fic_N PF13784.1 EGC37511.1 - 0.045 13.6 0.1 0.12 12.2 0.1 1.8 1 0 0 1 1 1 0 Fic/DOC family N-terminal DUF3744 PF12558.3 EGC37511.1 - 0.39 11.1 3.7 6.6 7.2 0.1 3.2 2 1 0 2 2 2 0 ATP-binding cassette cobalt transporter DUF2115 PF09888.4 EGC37511.1 - 3.6 7.6 9.4 0.79 9.8 2.1 2.7 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2115) Transaldolase PF00923.14 EGC37513.1 - 1.2e-91 306.7 0.5 1.4e-91 306.6 0.3 1.0 1 0 0 1 1 1 1 Transaldolase Prenyltrans_1 PF13243.1 EGC37513.1 - 0.029 14.3 0.0 3.7 7.5 0.0 2.4 2 1 0 2 2 2 0 Prenyltransferase-like DUF3843 PF12954.2 EGC37513.1 - 0.04 12.9 0.1 0.083 11.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3843) PIH1 PF08190.7 EGC37514.1 - 2.7e-15 56.6 16.3 5.1e-11 42.5 3.5 3.9 2 1 2 4 4 4 2 pre-RNA processing PIH1/Nop17 Peptidase_M8 PF01457.11 EGC37515.1 - 9.2e-49 166.1 2.3 1.7e-48 165.2 1.6 1.4 1 0 0 1 1 1 1 Leishmanolysin Pox_G7 PF05503.7 EGC37516.1 - 0.02 13.5 0.0 0.02 13.5 0.0 1.2 1 0 0 1 1 1 0 Poxvirus G7-like FNIP PF05725.7 EGC37519.1 - 8.1e-27 92.9 69.4 5.7e-08 32.5 0.4 13.2 8 4 5 13 13 13 9 FNIP Repeat ubiquitin PF00240.18 EGC37520.1 - 4.9e-06 25.8 0.0 5.9e-06 25.5 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGC37520.1 - 0.01 16.0 0.0 0.011 16.0 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-like domain Rad60-SLD PF11976.3 EGC37520.1 - 0.037 13.7 0.0 0.043 13.5 0.0 1.1 1 0 0 1 1 1 0 Ubiquitin-2 like Rad60 SUMO-like Methyltransf_11 PF08241.7 EGC37521.1 - 5.2e-07 30.0 0.0 1e-06 29.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC37521.1 - 6.6e-06 25.7 0.6 9.8e-06 25.2 0.4 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGC37521.1 - 1.6e-05 24.6 0.1 2.3e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC37521.1 - 0.00016 22.0 0.2 0.00036 20.9 0.1 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC37521.1 - 0.00037 20.2 0.0 0.00053 19.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC37521.1 - 0.001 19.6 0.1 0.0015 19.0 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37521.1 - 0.0033 17.7 0.0 0.0059 16.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MetW PF07021.7 EGC37521.1 - 0.0056 16.0 0.4 0.01 15.2 0.3 1.4 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW SNO PF01174.14 EGC37521.1 - 0.018 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 SNO glutamine amidotransferase family MTS PF05175.9 EGC37521.1 - 0.092 12.1 0.2 0.19 11.0 0.1 1.5 1 1 0 1 1 1 0 Methyltransferase small domain SpoIIE PF07228.7 EGC37523.1 - 4.9e-12 45.9 0.0 7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 Stage II sporulation protein E (SpoIIE) PP2C PF00481.16 EGC37523.1 - 4.3e-08 32.8 0.8 0.0051 16.2 0.0 2.9 3 1 0 3 3 3 2 Protein phosphatase 2C PP2C_2 PF13672.1 EGC37523.1 - 1.3e-06 27.9 2.2 6.8e-06 25.6 0.0 2.6 3 0 0 3 3 3 1 Protein phosphatase 2C Coprogen_oxidas PF01218.13 EGC37524.1 - 1.4e-98 329.1 1.0 6.7e-98 326.8 0.7 1.8 1 1 0 1 1 1 1 Coproporphyrinogen III oxidase DUF577 PF04510.7 EGC37525.1 - 0.0081 15.8 0.1 0.0093 15.6 0.1 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF577) Pox_A_type_inc PF04508.7 EGC37526.1 - 0.016 14.9 3.7 0.25 11.2 0.7 3.2 2 0 0 2 2 2 0 Viral A-type inclusion protein repeat CLU_N PF15044.1 EGC37526.1 - 0.046 13.8 0.3 0.17 12.0 0.1 2.0 2 0 0 2 2 2 0 Mitochondrial function, CLU-N-term Peptidase_S49_N PF08496.5 EGC37526.1 - 8.5 6.1 15.9 0.84 9.4 5.7 2.4 2 0 0 2 2 2 0 Peptidase family S49 N-terminal Peptidase_M16_C PF05193.16 EGC37527.1 - 2.1e-37 128.5 0.0 3e-37 128.0 0.0 1.2 1 0 0 1 1 1 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC37527.1 - 0.00024 20.9 0.0 0.00053 19.7 0.0 1.6 1 0 0 1 1 1 1 Insulinase (Peptidase family M16) Tmemb_14 PF03647.8 EGC37528.1 - 8.3e-25 87.0 13.4 9.4e-25 86.8 9.3 1.0 1 0 0 1 1 1 1 Transmembrane proteins 14C UbiA PF01040.13 EGC37528.1 - 0.0062 15.7 12.4 0.0068 15.6 8.6 1.0 1 0 0 1 1 1 1 UbiA prenyltransferase family DUF4064 PF13273.1 EGC37528.1 - 7 6.8 7.4 20 5.3 4.8 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) DUF504 PF04457.7 EGC37529.1 - 8.5e-05 22.6 1.2 0.0038 17.3 0.8 2.7 1 1 0 1 1 1 1 Protein of unknown function (DUF504) vATP-synt_E PF01991.13 EGC37529.1 - 0.004 16.4 5.2 0.0061 15.8 3.6 1.3 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit OSCP PF00213.13 EGC37529.1 - 0.076 12.8 2.2 0.13 12.1 1.6 1.4 1 0 0 1 1 1 0 ATP synthase delta (OSCP) subunit DUF3646 PF12362.3 EGC37529.1 - 0.097 12.6 0.5 0.16 11.9 0.3 1.3 1 0 0 1 1 1 0 DNA polymerase III gamma and tau subunits C terminal Maelstrom PF13017.1 EGC37529.1 - 0.11 11.9 3.1 0.13 11.7 1.3 1.7 1 1 1 2 2 2 0 piRNA pathway germ-plasm component K-box PF01486.12 EGC37529.1 - 2.4 8.0 12.4 0.5 10.1 6.4 1.5 2 0 0 2 2 2 0 K-box region Med2 PF11214.3 EGC37529.1 - 4.3 7.4 10.6 9 6.3 7.4 1.6 1 1 0 1 1 1 0 Mediator complex subunit 2 DUF846 PF05832.7 EGC37530.1 - 8.8e-50 168.0 14.5 1.2e-49 167.7 10.0 1.2 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF846) Mic1 PF07035.7 EGC37531.1 - 4.2e-30 104.2 1.0 1.2e-29 102.8 0.7 1.8 1 0 0 1 1 1 1 Colon cancer-associated protein Mic1-like Fz PF01392.17 EGC37532.1 - 1.2e-05 25.6 7.4 2.5e-05 24.6 5.1 1.6 1 0 0 1 1 1 1 Fz domain DUF4412 PF14371.1 EGC37532.1 - 0.00033 21.1 0.0 0.00069 20.0 0.0 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4412) DRY_EERY PF09750.4 EGC37532.1 - 0.048 13.7 0.0 0.081 13.0 0.0 1.3 1 0 0 1 1 1 0 Alternative splicing regulator Ependymin PF00811.13 EGC37532.1 - 0.052 13.2 0.2 0.099 12.3 0.1 1.5 1 0 0 1 1 1 0 Ependymin MIF4G PF02854.14 EGC37533.1 - 9.4e-33 113.3 6.6 1.1e-32 113.1 4.6 1.1 1 0 0 1 1 1 1 MIF4G domain TPR_11 PF13414.1 EGC37534.1 - 6e-09 35.4 0.1 0.012 15.2 0.0 3.8 2 1 2 4 4 4 2 TPR repeat TPR_8 PF13181.1 EGC37534.1 - 4.3e-08 32.3 4.2 0.00089 18.8 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC37534.1 - 6.4e-08 32.1 0.2 0.0045 17.0 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC37534.1 - 9.4e-08 31.4 1.3 0.12 12.3 0.0 5.3 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37534.1 - 5.3e-05 22.6 3.6 0.23 11.1 0.0 4.5 5 0 0 5 5 5 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37534.1 - 9.9e-05 22.6 0.0 0.18 12.1 0.0 2.6 2 1 0 2 2 2 2 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37534.1 - 0.0084 16.0 0.0 0.094 12.6 0.0 2.5 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC37534.1 - 0.019 15.5 0.0 24 5.8 0.0 4.1 3 2 1 4 4 4 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37534.1 - 0.054 14.1 0.0 2.8 8.7 0.0 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC37534.1 - 0.076 12.9 0.1 27 4.7 0.0 3.4 3 0 0 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EGC37534.1 - 0.076 12.8 1.8 0.72 9.7 0.0 3.3 4 1 0 4 4 4 0 Tetratricopeptide repeat TOM20_plant PF06552.7 EGC37534.1 - 0.13 11.8 1.7 59 3.1 0.1 3.1 1 1 1 3 3 3 0 Plant specific mitochondrial import receptor subunit TOM20 Abhydrolase_6 PF12697.2 EGC37535.1 - 6.2e-15 55.7 0.0 7.9e-15 55.3 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC37535.1 - 7.5e-08 32.2 0.0 1.2e-07 31.4 0.0 1.4 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC37535.1 - 2.7e-06 27.1 0.0 3.9e-06 26.6 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Ndr PF03096.9 EGC37535.1 - 0.019 13.4 0.4 0.035 12.5 0.0 1.5 2 0 0 2 2 2 0 Ndr family DUF4211 PF13926.1 EGC37535.1 - 0.023 14.0 1.6 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4211) FSH1 PF03959.8 EGC37535.1 - 0.027 13.9 0.0 0.14 11.6 0.0 2.2 2 1 0 2 2 2 0 Serine hydrolase (FSH1) Stathmin PF00836.14 EGC37535.1 - 0.21 11.2 5.3 0.8 9.3 0.5 2.2 2 0 0 2 2 2 0 Stathmin family zf-Apc11 PF12861.2 EGC37536.1 - 1.5e-31 108.0 17.6 1.7e-31 107.9 12.2 1.0 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-rbx1 PF12678.2 EGC37536.1 - 2.4e-29 101.2 19.7 2.9e-29 100.9 13.7 1.1 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGC37536.1 - 1.7e-07 30.9 18.6 4.8e-07 29.5 12.9 1.7 1 1 0 1 1 1 1 Ring finger domain zf-Nse PF11789.3 EGC37536.1 - 0.0059 16.0 8.1 0.013 14.9 5.6 1.6 1 1 0 1 1 1 1 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4 PF00097.20 EGC37536.1 - 0.016 14.8 19.5 0.023 14.3 12.0 2.3 1 1 1 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37536.1 - 0.04 13.9 17.7 0.53 10.3 12.3 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37536.1 - 0.21 11.3 17.6 1.4 8.7 12.3 2.1 1 1 1 2 2 2 0 zinc-RING finger domain RINGv PF12906.2 EGC37536.1 - 1 9.4 14.5 0.052 13.5 5.1 2.3 2 1 0 2 2 2 0 RING-variant domain zf-HC5HC2H_2 PF13832.1 EGC37536.1 - 1.8 8.5 11.5 3.6 7.6 7.9 1.6 1 1 0 1 1 1 0 PHD-zinc-finger like domain FANCL_C PF11793.3 EGC37536.1 - 6.6 6.7 16.4 56 3.8 11.3 2.2 1 1 0 1 1 1 0 FANCL C-terminal domain ABC2_membrane PF01061.19 EGC37539.1 - 2.3e-36 124.9 16.8 2.3e-36 124.9 11.6 1.6 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC37539.1 - 1.6e-25 90.0 0.0 2.6e-25 89.2 0.0 1.4 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC37539.1 - 1e-07 32.2 3.6 1.1e-05 25.5 0.0 3.2 2 1 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGC37539.1 - 3e-07 29.7 12.7 3e-07 29.7 8.8 1.7 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_29 PF13555.1 EGC37539.1 - 6.7e-05 22.3 0.1 0.00015 21.1 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC37539.1 - 0.00016 20.8 0.1 0.00029 20.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC37539.1 - 0.00025 20.5 0.0 0.0013 18.1 0.0 2.0 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC37539.1 - 0.00078 19.4 0.0 0.0011 18.9 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGC37539.1 - 0.00079 19.5 0.1 0.0059 16.7 0.1 2.4 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC37539.1 - 0.0024 18.6 0.0 0.0066 17.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC37539.1 - 0.0041 17.4 1.0 0.0072 16.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC37539.1 - 0.0057 15.7 7.5 0.38 9.7 0.8 3.0 2 1 1 3 3 2 2 AAA ATPase domain Arch_ATPase PF01637.13 EGC37539.1 - 0.0062 16.2 0.2 0.017 14.8 0.1 1.8 2 0 0 2 2 1 1 Archaeal ATPase SMC_N PF02463.14 EGC37539.1 - 0.014 14.6 0.1 0.2 10.8 0.1 2.4 1 1 0 1 1 1 0 RecF/RecN/SMC N terminal domain AAA_33 PF13671.1 EGC37539.1 - 0.037 13.9 0.0 0.072 12.9 0.0 1.5 1 0 0 1 1 1 0 AAA domain AmoA PF05145.7 EGC37539.1 - 0.045 12.7 3.1 0.069 12.1 2.2 1.2 1 0 0 1 1 1 0 Putative ammonia monooxygenase SbcCD_C PF13558.1 EGC37539.1 - 0.049 13.5 0.1 0.3 11.0 0.1 2.2 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_28 PF13521.1 EGC37539.1 - 0.07 13.0 0.2 0.12 12.2 0.2 1.4 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGC37539.1 - 0.11 12.0 0.2 0.27 10.8 0.1 1.6 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EGC37539.1 - 0.12 11.8 0.0 0.2 11.0 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_23 PF13476.1 EGC37539.1 - 0.27 11.5 0.1 0.27 11.5 0.1 2.4 1 1 1 2 2 1 0 AAA domain PDR_CDR PF06422.7 EGC37539.1 - 0.81 9.3 5.7 0.13 11.9 0.2 2.6 2 0 0 2 2 1 0 CDR ABC transporter MMgT PF10270.4 EGC37539.1 - 0.88 10.0 4.6 0.34 11.3 0.3 2.2 2 0 0 2 2 2 0 Membrane magnesium transporter Mhr1 PF12829.2 EGC37540.1 - 0.0029 17.3 0.8 0.0053 16.5 0.6 1.4 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination RAI1 PF08652.6 EGC37540.1 - 0.23 11.2 3.5 0.83 9.4 2.4 2.0 1 1 0 1 1 1 0 RAI1 like PD-(D/E)XK nuclease Av_adeno_fibre PF06536.6 EGC37540.1 - 0.27 10.9 3.1 9.6 5.9 0.1 2.3 1 1 1 2 2 2 0 Avian adenovirus fibre EGF_2 PF07974.8 EGC37541.1 - 0.013 15.5 2.3 0.026 14.7 1.6 1.5 1 0 0 1 1 1 0 EGF-like domain EGF_alliinase PF04863.8 EGC37541.1 - 0.027 14.4 1.9 0.027 14.4 1.3 1.4 2 0 0 2 2 2 0 Alliinase EGF-like domain Laminin_EGF PF00053.19 EGC37541.1 - 0.08 12.8 1.2 0.097 12.6 0.9 1.3 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) Orthopox_F6 PF06601.7 EGC37541.1 - 2.2 8.2 4.9 2 8.4 1.1 1.9 1 1 1 2 2 2 0 Orthopoxvirus F6 protein Cwf_Cwc_15 PF04889.7 EGC37542.1 - 0.019 14.7 22.7 0.029 14.0 15.8 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein Shisa PF13908.1 EGC37543.1 - 0.00026 21.1 5.7 0.00027 21.1 4.0 1.0 1 0 0 1 1 1 1 Wnt and FGF inhibitory regulator Serinc PF03348.10 EGC37543.1 - 0.00091 18.0 2.4 0.001 17.9 1.7 1.0 1 0 0 1 1 1 1 Serine incorporator (Serinc) Ctr PF04145.10 EGC37543.1 - 0.0011 19.0 0.2 0.0014 18.7 0.1 1.0 1 0 0 1 1 1 1 Ctr copper transporter family SpoIIIAH PF12685.2 EGC37543.1 - 0.0012 18.4 0.8 0.0013 18.2 0.5 1.0 1 0 0 1 1 1 1 SpoIIIAH-like protein YfhO PF09586.5 EGC37543.1 - 0.0025 15.9 2.6 0.0026 15.8 1.8 1.0 1 0 0 1 1 1 1 Bacterial membrane protein YfhO DUF2681 PF10883.3 EGC37543.1 - 0.0028 17.8 4.6 0.0033 17.5 3.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2681) Potyvirid-P3 PF13608.1 EGC37543.1 - 0.0034 16.5 2.8 0.0037 16.4 1.9 1.0 1 0 0 1 1 1 1 Protein P3 of Potyviral polyprotein PIG-P PF08510.7 EGC37543.1 - 0.0034 16.9 0.7 0.0037 16.9 0.5 1.1 1 0 0 1 1 1 1 PIG-P DUF2149 PF09919.4 EGC37543.1 - 0.0048 16.9 0.7 0.0053 16.8 0.5 1.1 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2149) Zip PF02535.17 EGC37543.1 - 0.005 15.9 2.0 0.0056 15.7 1.4 1.0 1 0 0 1 1 1 1 ZIP Zinc transporter Mucin PF01456.12 EGC37543.1 - 0.0067 16.2 2.6 0.0076 16.0 1.8 1.1 1 0 0 1 1 1 1 Mucin-like glycoprotein RCR PF12273.3 EGC37543.1 - 0.0082 16.6 6.7 0.012 16.1 4.6 1.2 1 0 0 1 1 1 1 Chitin synthesis regulation, resistance to Congo red FAM176 PF14851.1 EGC37543.1 - 0.01 15.4 0.5 0.011 15.3 0.3 1.0 1 0 0 1 1 1 0 FAM176 family OSTbeta PF15048.1 EGC37543.1 - 0.012 15.7 0.1 0.012 15.6 0.1 1.1 1 0 0 1 1 1 0 Organic solute transporter subunit beta protein DUF4064 PF13273.1 EGC37543.1 - 0.014 15.4 0.2 0.017 15.2 0.1 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4064) DUF106 PF01956.11 EGC37543.1 - 0.015 14.7 1.4 0.018 14.6 1.0 1.0 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF2547 PF10818.3 EGC37543.1 - 0.021 15.4 13.3 0.025 15.1 9.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2547) DUF3365 PF11845.3 EGC37543.1 - 0.022 14.5 1.0 0.027 14.3 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3365) AIF_C PF14721.1 EGC37543.1 - 0.025 14.8 1.3 0.026 14.7 0.9 1.1 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PDR_CDR PF06422.7 EGC37543.1 - 0.025 14.2 0.1 0.033 13.8 0.1 1.2 1 0 0 1 1 1 0 CDR ABC transporter SelP_N PF04592.9 EGC37543.1 - 0.041 13.2 9.2 0.044 13.1 6.4 1.0 1 0 0 1 1 1 0 Selenoprotein P, N terminal region FHIPEP PF00771.15 EGC37543.1 - 0.043 12.1 0.7 0.046 12.0 0.5 1.0 1 0 0 1 1 1 0 FHIPEP family DUF788 PF05620.6 EGC37543.1 - 0.046 13.5 0.8 0.067 13.0 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Mlo PF03094.10 EGC37543.1 - 0.051 11.6 0.1 0.063 11.3 0.1 1.1 1 0 0 1 1 1 0 Mlo family FAM163 PF15069.1 EGC37543.1 - 0.058 13.9 0.5 0.063 13.8 0.4 1.0 1 0 0 1 1 1 0 FAM163 family SID-1_RNA_chan PF13965.1 EGC37543.1 - 0.058 11.5 2.3 0.06 11.5 1.6 1.0 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 FimP PF09766.4 EGC37543.1 - 0.063 12.3 10.8 0.06 12.4 7.5 1.1 1 0 0 1 1 1 0 Fms-interacting protein Nucleoside_tran PF01733.13 EGC37543.1 - 0.076 12.1 0.2 0.085 12.0 0.1 1.0 1 0 0 1 1 1 0 Nucleoside transporter Chordopox_G3 PF06129.7 EGC37543.1 - 0.079 13.1 0.7 0.11 12.6 0.5 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein SHR3_chaperone PF08229.6 EGC37543.1 - 0.083 11.8 2.9 0.1 11.5 2.0 1.2 1 0 0 1 1 1 0 ER membrane protein SH3 IncA PF04156.9 EGC37543.1 - 0.086 12.4 4.4 0.097 12.2 3.1 1.1 1 0 0 1 1 1 0 IncA protein DUF914 PF06027.7 EGC37543.1 - 0.089 11.6 0.4 0.099 11.4 0.3 1.1 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF914) YqfQ PF14181.1 EGC37543.1 - 0.09 12.8 9.2 0.1 12.6 6.4 1.0 1 0 0 1 1 1 0 YqfQ-like protein Spt20 PF12090.3 EGC37543.1 - 0.093 12.0 8.9 0.1 11.9 6.2 1.1 1 0 0 1 1 1 0 Spt20 family GRP PF07172.6 EGC37543.1 - 0.098 13.1 0.0 0.13 12.7 0.0 1.1 1 0 0 1 1 1 0 Glycine rich protein family ETRAMP PF09716.5 EGC37543.1 - 0.098 12.6 0.1 0.13 12.2 0.0 1.1 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF2140 PF09911.4 EGC37543.1 - 0.1 11.7 1.2 0.12 11.5 0.9 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2140) Neur_chan_memb PF02932.11 EGC37543.1 - 0.11 12.3 2.4 0.12 12.2 1.6 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1980 PF09323.5 EGC37543.1 - 0.13 12.0 1.8 0.16 11.7 1.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1980) Kei1 PF08552.6 EGC37543.1 - 0.13 11.8 2.8 0.16 11.6 2.0 1.1 1 0 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF4199 PF13858.1 EGC37543.1 - 0.13 12.1 3.0 0.15 11.9 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4199) TMEM51 PF15345.1 EGC37543.1 - 0.13 11.8 3.8 0.15 11.7 2.7 1.1 1 0 0 1 1 1 0 Transmembrane protein 51 DUF3260 PF11658.3 EGC37543.1 - 0.15 10.1 3.7 0.16 10.1 2.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3260) OATP PF03137.15 EGC37543.1 - 0.15 10.0 4.2 0.18 9.8 2.9 1.0 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Endonuc_Holl PF10107.4 EGC37543.1 - 0.19 11.3 2.2 0.21 11.2 1.5 1.0 1 0 0 1 1 1 0 Endonuclease related to archaeal Holliday junction resolvase Gti1_Pac2 PF09729.4 EGC37543.1 - 0.2 11.5 4.8 0.23 11.3 3.3 1.1 1 0 0 1 1 1 0 Gti1/Pac2 family DUF2232 PF09991.4 EGC37543.1 - 0.21 10.5 2.2 0.22 10.4 1.5 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Stig1 PF04885.8 EGC37543.1 - 0.22 11.7 2.4 0.24 11.5 1.7 1.1 1 0 0 1 1 1 0 Stigma-specific protein, Stig1 PH_4 PF15404.1 EGC37543.1 - 0.26 10.8 5.6 0.29 10.6 3.9 1.1 1 0 0 1 1 1 0 Pleckstrin homology domain PP_M1 PF03012.9 EGC37543.1 - 0.35 10.1 4.7 0.36 10.1 3.3 1.0 1 0 0 1 1 1 0 Phosphoprotein DUF3357 PF11837.3 EGC37543.1 - 0.42 10.4 3.6 3.4 7.5 2.5 2.0 1 1 0 1 1 1 0 Domain of unknown function (DUF3357) DUF4512 PF14975.1 EGC37543.1 - 0.42 11.4 3.4 0.51 11.1 2.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) DUF3573 PF12097.3 EGC37543.1 - 0.61 8.6 5.6 0.65 8.5 3.9 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DivIC PF04977.10 EGC37543.1 - 0.7 9.4 7.0 1 8.9 4.8 1.3 1 0 0 1 1 1 0 Septum formation initiator Pex16 PF08610.5 EGC37543.1 - 0.72 8.7 4.7 0.73 8.7 3.3 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) Presenilin PF01080.12 EGC37543.1 - 0.91 8.2 2.8 1 8.0 1.9 1.1 1 0 0 1 1 1 0 Presenilin SIT PF15330.1 EGC37543.1 - 0.92 9.6 8.0 1.2 9.2 5.6 1.2 1 0 0 1 1 1 0 SHP2-interacting transmembrane adaptor protein, SIT CPSF100_C PF13299.1 EGC37543.1 - 1.2 9.2 8.4 1.3 9.1 5.8 1.0 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal Plasmodium_Vir PF05795.6 EGC37543.1 - 1.3 8.1 4.4 1.5 7.9 3.1 1.1 1 0 0 1 1 1 0 Plasmodium vivax Vir protein DUF4557 PF15101.1 EGC37543.1 - 1.6 8.4 14.6 1.8 8.3 10.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) ODV-E18 PF10717.4 EGC37543.1 - 2.2 7.7 6.3 74 2.8 4.4 2.1 1 1 0 1 1 1 0 Occlusion-derived virus envelope protein ODV-E18 Band_3_cyto PF07565.8 EGC37543.1 - 2.6 7.4 8.0 2.7 7.4 5.5 1.0 1 0 0 1 1 1 0 Band 3 cytoplasmic domain FCP1_C PF09309.5 EGC37543.1 - 3 7.0 10.7 3.4 6.8 7.4 1.1 1 0 0 1 1 1 0 FCP1, C-terminal RED_N PF07808.8 EGC37543.1 - 3.3 6.8 12.0 3.8 6.6 8.3 1.0 1 0 0 1 1 1 0 RED-like protein N-terminal region BRF1 PF07741.8 EGC37543.1 - 3.9 7.7 8.9 4.8 7.4 6.2 1.1 1 0 0 1 1 1 0 Brf1-like TBP-binding domain Suf PF05843.9 EGC37543.1 - 4.9 6.8 11.6 5.2 6.7 8.0 1.1 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) EphA2_TM PF14575.1 EGC37543.1 - 5.6 7.4 9.6 88 3.6 6.7 2.0 1 1 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain AUX_IAA PF02309.11 EGC37543.1 - 6.5 6.4 9.7 7.5 6.2 6.7 1.0 1 0 0 1 1 1 0 AUX/IAA family Tim54 PF11711.3 EGC37543.1 - 7.6 5.0 9.2 8.7 4.8 6.4 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DUF775 PF05603.7 EGC37543.1 - 8.5 5.8 10.6 10 5.5 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF775) BAF1_ABF1 PF04684.8 EGC37543.1 - 9.3 4.9 24.9 11 4.7 17.3 1.0 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor UPF0560 PF10577.4 EGC37543.1 - 9.4 4.3 12.4 9.9 4.2 8.6 1.0 1 0 0 1 1 1 0 Uncharacterised protein family UPF0560 DUF4175 PF13779.1 EGC37543.1 - 9.8 3.7 22.7 10 3.6 15.7 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Ank_2 PF12796.2 EGC37544.1 - 0.00059 20.1 0.0 0.82 10.0 0.0 3.0 3 0 0 3 3 3 2 Ankyrin repeats (3 copies) Activator_LAG-3 PF11498.3 EGC37544.1 - 0.65 8.6 10.8 0.98 8.0 7.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 Ferrochelatase PF00762.14 EGC37545.1 - 4.9e-104 347.7 0.0 6.1e-104 347.3 0.0 1.1 1 0 0 1 1 1 1 Ferrochelatase KfrA_N PF11740.3 EGC37545.1 - 0.21 12.0 0.0 0.76 10.2 0.0 1.9 1 0 0 1 1 1 0 Plasmid replication region DNA-binding N-term Metallophos_2 PF12850.2 EGC37546.1 - 4.4e-23 81.8 0.1 5.2e-23 81.6 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGC37546.1 - 2.6e-05 23.7 0.5 0.012 15.0 0.1 2.2 1 1 1 2 2 2 2 Calcineurin-like phosphoesterase Xan_ur_permease PF00860.15 EGC37547.1 - 1.6e-77 260.6 40.9 2.2e-77 260.1 28.3 1.1 1 0 0 1 1 1 1 Permease family CAP_N PF01213.14 EGC37548.1 - 1.9e-110 369.0 5.8 2.6e-110 368.6 4.0 1.1 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) N terminal CAP_C PF08603.6 EGC37548.1 - 3.5e-63 211.7 8.6 5.4e-63 211.0 6.0 1.3 1 0 0 1 1 1 1 Adenylate cyclase associated (CAP) C terminal TBCC PF07986.7 EGC37548.1 - 0.00057 19.2 4.8 0.0011 18.4 3.3 1.4 1 0 0 1 1 1 1 Tubulin binding cofactor C Ribosomal_60s PF00428.14 EGC37548.1 - 0.067 13.5 0.1 0.067 13.5 0.1 3.1 4 0 0 4 4 4 0 60s Acidic ribosomal protein TroA PF01297.12 EGC37548.1 - 0.082 12.1 1.3 0.15 11.3 0.9 1.5 1 0 0 1 1 1 0 Periplasmic solute binding protein family FliD_N PF02465.13 EGC37548.1 - 4.4 7.7 13.4 0.45 10.8 0.2 3.6 3 0 0 3 3 3 0 Flagellar hook-associated protein 2 N-terminus DUF2418 PF10332.4 EGC37549.1 - 1.3e-16 60.7 1.0 1.3e-16 60.7 0.7 2.3 3 0 0 3 3 3 1 Protein of unknown function (DUF2418) Colicin_V PF02674.11 EGC37549.1 - 5.2 6.9 9.9 16 5.2 6.9 1.7 1 1 0 1 1 1 0 Colicin V production protein GST_N PF02798.15 EGC37550.1 - 3e-12 46.5 0.0 9.3e-12 44.9 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_N_3 PF13417.1 EGC37550.1 - 2.6e-11 43.5 0.0 6.1e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC37550.1 - 6e-10 38.9 0.3 1.5e-09 37.7 0.2 1.7 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC37550.1 - 0.00017 21.5 0.0 0.00034 20.5 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC37550.1 - 0.0023 18.3 0.0 0.0033 17.8 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_2 PF13410.1 EGC37550.1 - 0.0049 16.7 0.0 0.0092 15.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain FNIP PF05725.7 EGC37551.1 - 2.1e-188 610.1 65.2 5.1e-17 61.5 0.0 14.1 3 3 12 18 18 18 18 FNIP Repeat LRR_5 PF13306.1 EGC37551.1 - 3.1e-10 39.8 2.9 0.00076 19.1 0.0 4.5 2 2 2 4 4 4 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC37551.1 - 4.5e-09 36.1 26.8 7.9 6.5 0.3 13.5 5 4 10 16 16 16 4 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC37551.1 - 0.013 15.4 0.1 20 5.1 0.0 4.6 4 1 0 4 4 4 0 Phage minor tail protein PP1_bind PF15276.1 EGC37551.1 - 0.1 12.6 10.1 1.2e+02 2.8 0.0 8.5 9 2 2 11 11 11 0 Protein phosphatase 1 binding COG7 PF10191.4 EGC37553.1 - 8.6e-102 341.4 44.6 2.6e-85 286.9 19.9 3.1 2 1 1 3 3 3 3 Golgi complex component 7 (COG7) Fz PF01392.17 EGC37554.1 - 0.00015 22.1 6.3 0.00036 20.8 4.4 1.7 1 0 0 1 1 1 1 Fz domain DUF4412 PF14371.1 EGC37554.1 - 0.02 15.3 0.1 0.042 14.3 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4412) Init_tRNA_PT PF04179.7 EGC37555.1 - 1.7e-127 426.0 7.8 2e-127 425.7 5.4 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase FNIP PF05725.7 EGC37556.1 - 2.2e-72 238.7 36.0 3.7e-15 55.6 0.6 6.6 6 1 1 7 7 7 6 FNIP Repeat LRR_5 PF13306.1 EGC37556.1 - 0.00042 20.0 3.1 0.00066 19.3 0.8 2.1 2 1 0 2 2 2 1 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC37556.1 - 0.055 13.4 7.1 17 5.4 0.0 5.1 3 2 3 6 6 6 0 Protein of unknown function (DUF1769) PP1_bind PF15276.1 EGC37556.1 - 0.21 11.6 1.7 77 3.4 0.0 4.1 3 1 0 3 3 3 0 Protein phosphatase 1 binding Voltage_CLC PF00654.15 EGC37557.1 - 2.9e-64 217.3 28.2 2.9e-64 217.3 19.6 2.0 1 1 1 2 2 2 1 Voltage gated chloride channel CBS PF00571.23 EGC37557.1 - 4.5e-10 39.1 0.3 4.2e-05 23.2 0.0 2.6 2 0 0 2 2 2 2 CBS domain HALZ PF02183.13 EGC37558.1 - 0.023 14.4 0.4 0.061 13.0 0.3 1.7 1 0 0 1 1 1 0 Homeobox associated leucine zipper LRR_6 PF13516.1 EGC37558.1 - 3.7 7.9 17.5 0.57 10.4 1.4 4.3 4 0 0 4 4 4 0 Leucine Rich repeat LRR_7 PF13504.1 EGC37558.1 - 6.5 7.4 8.8 35 5.2 0.3 4.5 4 0 0 4 4 4 0 Leucine rich repeat LRR_1 PF00560.28 EGC37558.1 - 6.8 7.1 12.4 3.5 8.0 1.3 3.8 3 0 0 3 3 3 0 Leucine Rich Repeat TAFH PF07531.9 EGC37560.1 - 0.092 12.3 0.7 0.14 11.8 0.1 1.6 2 0 0 2 2 2 0 NHR1 homology to TAF Peptidase_S24 PF00717.18 EGC37561.1 - 4e-08 32.7 0.2 6.2e-08 32.1 0.2 1.3 1 0 0 1 1 1 1 Peptidase S24-like TLD PF07534.11 EGC37562.1 - 6e-38 129.9 3.3 9.9e-38 129.2 0.8 2.7 2 0 0 2 2 2 1 TLD WD40 PF00400.27 EGC37562.1 - 2.5e-06 27.1 12.1 0.00044 20.0 0.4 5.1 6 0 0 6 6 6 3 WD domain, G-beta repeat LysM PF01476.15 EGC37562.1 - 2.7e-06 27.1 0.1 2.2e-05 24.2 0.0 2.5 2 0 0 2 2 2 1 LysM domain GRAM PF02893.15 EGC37562.1 - 0.00069 19.0 0.1 0.0019 17.7 0.0 1.7 1 0 0 1 1 1 1 GRAM domain Tweety PF04906.8 EGC37563.1 - 8.6e-05 21.1 6.8 0.0077 14.6 0.9 2.5 2 0 0 2 2 2 2 Tweety Polysacc_synt PF01943.12 EGC37563.1 - 0.0011 18.2 1.0 0.0011 18.2 0.7 2.9 5 0 0 5 5 5 1 Polysaccharide biosynthesis protein DUF2207 PF09972.4 EGC37563.1 - 0.0088 14.6 4.3 0.05 12.1 0.5 2.4 2 0 0 2 2 2 1 Predicted membrane protein (DUF2207) DUF2668 PF10873.3 EGC37563.1 - 0.018 15.1 2.3 0.018 15.1 1.6 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF2668) Flagellin_N PF00669.15 EGC37563.1 - 0.064 13.0 3.4 0.41 10.4 2.6 2.0 2 0 0 2 2 2 0 Bacterial flagellin N-terminal helical region DUF4131 PF13567.1 EGC37563.1 - 0.089 12.1 5.1 1.5 8.1 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF148 PF02520.12 EGC37563.1 - 0.26 11.0 3.4 0.51 10.1 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function DUF148 Wzy_C PF04932.10 EGC37563.1 - 2.2 8.0 11.2 13 5.5 3.5 3.1 2 1 0 2 2 2 0 O-Antigen ligase DUF1628 PF07790.6 EGC37563.1 - 2.5 8.9 9.4 1.6 9.5 0.0 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) MBOAT PF03062.14 EGC37565.1 - 1.4e-11 44.1 24.2 1.4e-11 44.1 16.8 1.5 1 1 0 1 1 1 1 MBOAT, membrane-bound O-acyltransferase family DUF1365 PF07103.6 EGC37566.1 - 3.2e-53 180.3 0.1 5.7e-53 179.5 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1365) YL1_C PF08265.6 EGC37567.1 - 0.0045 16.5 5.7 5.2 6.7 0.0 3.7 4 0 0 4 4 4 3 YL1 nuclear protein C-terminal domain DNA_pol3_a_NII PF11490.3 EGC37567.1 - 0.035 13.7 0.0 0.12 12.0 0.0 1.8 2 0 0 2 2 2 0 DNA polymerase III polC-type N-terminus II Baculo_PEP_C PF04513.7 EGC37567.1 - 0.11 12.3 26.7 1.7 8.4 0.8 5.0 5 0 0 5 5 5 0 Baculovirus polyhedron envelope protein, PEP, C terminus Reo_sigmaC PF04582.7 EGC37567.1 - 0.21 10.7 37.4 0.31 10.1 1.0 5.1 5 0 0 5 5 5 0 Reovirus sigma C capsid protein Vps51 PF08700.6 EGC37567.1 - 1.1 9.0 15.0 20 5.0 0.1 4.7 5 0 0 5 5 5 0 Vps51/Vps67 DUF2989 PF11207.3 EGC37567.1 - 1.5 8.2 5.8 5.8 6.3 1.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2989) HHH_8 PF14716.1 EGC37567.1 - 2.8 8.1 7.5 2.1e+02 2.2 0.0 4.7 5 0 0 5 5 5 0 Helix-hairpin-helix domain MCPsignal PF00015.16 EGC37567.1 - 4.3 6.8 33.7 7.2 6.0 1.4 5.0 5 0 0 5 5 5 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Nup35_RRM PF05172.8 EGC37568.1 - 5.7e-08 32.4 0.1 1.8e-07 30.8 0.0 1.8 1 1 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGC37568.1 - 8.2e-07 28.6 0.0 1.4e-06 27.9 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif RRM_6 PF14259.1 EGC37568.1 - 0.016 15.1 0.0 0.028 14.4 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC37568.1 - 0.079 12.6 0.0 0.14 11.8 0.0 1.3 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RseC_MucC PF04246.7 EGC37568.1 - 0.66 9.5 3.8 0.31 10.5 0.1 2.3 2 1 0 2 2 2 0 Positive regulator of sigma(E), RseC/MucC Thioredoxin PF00085.15 EGC37569.1 - 2.3e-27 94.6 1.3 9e-27 92.7 0.1 2.4 2 0 0 2 2 2 1 Thioredoxin UBX PF00789.15 EGC37569.1 - 1.1e-12 47.8 0.0 2.6e-12 46.6 0.0 1.7 1 0 0 1 1 1 1 UBX domain ZZ PF00569.12 EGC37569.1 - 2.6e-12 46.0 8.4 5e-12 45.1 5.8 1.5 1 0 0 1 1 1 1 Zinc finger, ZZ type Thioredoxin_8 PF13905.1 EGC37569.1 - 2.9e-05 24.0 0.0 9.1e-05 22.5 0.0 1.9 1 0 0 1 1 1 1 Thioredoxin-like UBA PF00627.26 EGC37569.1 - 4.5e-05 23.1 0.0 8.6e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 UBA/TS-N domain AhpC-TSA PF00578.16 EGC37569.1 - 0.00032 20.3 0.5 0.001 18.7 0.0 2.1 2 0 0 2 2 2 1 AhpC/TSA family Redoxin PF08534.5 EGC37569.1 - 0.00049 19.6 2.7 0.00085 18.8 0.1 2.4 2 1 1 3 3 3 1 Redoxin Thioredoxin_9 PF14595.1 EGC37569.1 - 0.0023 17.4 0.0 0.0023 17.4 0.0 2.9 4 0 0 4 4 4 1 Thioredoxin Thioredoxin_2 PF13098.1 EGC37569.1 - 0.0063 16.6 0.1 0.0063 16.6 0.1 3.0 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGC37569.1 - 0.009 16.0 0.0 0.022 14.7 0.0 1.7 1 0 0 1 1 1 1 Thioredoxin-like C1_2 PF03107.11 EGC37569.1 - 0.094 12.8 9.2 0.18 11.9 6.4 1.4 1 0 0 1 1 1 0 C1 domain Borrelia_P83 PF05262.6 EGC37569.1 - 0.54 8.4 16.4 0.91 7.7 11.4 1.3 1 0 0 1 1 1 0 Borrelia P83/100 protein C1_1 PF00130.17 EGC37569.1 - 0.98 9.1 6.4 5 6.9 4.4 2.2 1 1 1 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) HMG-CoA_red PF00368.13 EGC37571.1 - 7e-169 561.3 3.7 9.2e-169 560.9 2.6 1.1 1 0 0 1 1 1 1 Hydroxymethylglutaryl-coenzyme A reductase Mucin PF01456.12 EGC37572.1 - 1.2 8.8 26.9 2.2 8.0 18.7 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein Chalcone PF02431.10 EGC37573.1 - 1.8e-30 105.8 0.1 2.9e-30 105.1 0.1 1.3 1 1 0 1 1 1 1 Chalcone-flavanone isomerase Pik1 PF11522.3 EGC37573.1 - 0.22 11.2 5.8 0.12 12.1 0.3 3.1 3 0 0 3 3 3 0 Yeast phosphatidylinositol-4-OH kinase Pik1 Apis_Csd PF11671.3 EGC37573.1 - 0.77 9.5 9.9 0.047 13.4 2.9 1.8 2 0 0 2 2 2 0 Complementary sex determiner protein Lactamase_B_2 PF12706.2 EGC37574.1 - 1.4e-40 138.9 0.0 1.9e-34 118.8 0.0 2.3 2 0 0 2 2 2 2 Beta-lactamase superfamily domain Lactamase_B_4 PF13691.1 EGC37574.1 - 7.6e-12 44.5 0.0 1.7e-11 43.4 0.0 1.6 1 0 0 1 1 1 1 tRNase Z endonuclease Lactamase_B PF00753.22 EGC37574.1 - 8.1e-11 41.9 0.0 4.9e-07 29.5 0.0 2.5 2 0 0 2 2 2 2 Metallo-beta-lactamase superfamily SWIRM PF04433.12 EGC37575.1 - 4.5e-31 106.8 0.0 1.7e-30 104.9 0.0 2.1 1 0 0 1 1 1 1 SWIRM domain Acetyltransf_2 PF00797.12 EGC37575.1 - 3.7e-09 36.5 0.0 3.7e-09 36.5 0.0 2.9 3 0 0 3 3 3 1 N-acetyltransferase Myb_DNA-binding PF00249.26 EGC37575.1 - 1.6e-07 31.2 0.2 4.6e-07 29.7 0.0 1.9 2 0 0 2 2 2 1 Myb-like DNA-binding domain BRCT PF00533.21 EGC37575.1 - 0.0027 17.8 2.4 0.015 15.3 1.0 2.8 2 1 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Acetyltransf_2 PF00797.12 EGC37576.1 - 4.4e-16 59.2 0.0 6.6e-16 58.6 0.0 1.2 1 0 0 1 1 1 1 N-acetyltransferase SNARE PF05739.14 EGC37577.1 - 4.3e-14 51.9 4.1 4.3e-14 51.9 2.8 2.0 2 0 0 2 2 2 1 SNARE domain Syntaxin PF00804.20 EGC37577.1 - 1.1e-11 44.7 1.8 1.1e-11 44.7 1.2 2.4 2 1 0 2 2 2 1 Syntaxin MCPsignal PF00015.16 EGC37577.1 - 0.0069 15.9 1.4 0.012 15.1 0.2 1.8 2 1 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain RNA_pol_Rpc82 PF05645.8 EGC37577.1 - 0.0089 15.5 2.2 0.0089 15.5 1.5 1.9 2 1 0 2 2 2 1 RNA polymerase III subunit RPC82 RVT_3 PF13456.1 EGC37577.1 - 0.1 12.3 0.1 0.3 10.8 0.1 1.8 1 0 0 1 1 1 0 Reverse transcriptase-like LXG PF04740.7 EGC37577.1 - 0.12 12.1 9.4 0.026 14.3 2.7 2.5 1 1 1 2 2 2 0 LXG domain of WXG superfamily Syntaxin_2 PF14523.1 EGC37577.1 - 2.2 8.3 14.6 0.93 9.5 4.9 3.1 2 2 0 2 2 2 0 Syntaxin-like protein Med28 PF11594.3 EGC37577.1 - 4.1 7.7 10.1 0.45 10.7 0.6 2.9 1 1 1 2 2 2 0 Mediator complex subunit 28 OTU PF02338.14 EGC37578.1 - 1.8e-12 47.9 0.0 1.8e-12 47.9 0.0 2.0 2 0 0 2 2 2 1 OTU-like cysteine protease Thioredoxin PF00085.15 EGC37579.1 - 1.2e-27 95.5 0.0 1.3e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_8 PF13905.1 EGC37579.1 - 3.2e-06 27.1 0.0 3.4e-06 27.0 0.0 1.2 1 0 0 1 1 1 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC37579.1 - 1.7e-05 24.9 0.2 0.00023 21.3 0.1 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain Thioredoxin_7 PF13899.1 EGC37579.1 - 0.0017 18.3 0.1 0.0024 17.8 0.0 1.3 1 1 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EGC37579.1 - 0.0057 16.1 0.1 0.011 15.2 0.1 1.4 1 1 0 1 1 1 1 Redoxin Thioredoxin_9 PF14595.1 EGC37579.1 - 0.013 15.0 0.0 0.015 14.8 0.0 1.1 1 0 0 1 1 1 0 Thioredoxin AhpC-TSA PF00578.16 EGC37579.1 - 0.051 13.2 0.1 0.086 12.5 0.1 1.3 1 1 0 1 1 1 0 AhpC/TSA family Thioredoxin_4 PF13462.1 EGC37579.1 - 0.053 13.5 0.1 1.2 9.0 0.0 2.0 1 1 1 2 2 2 0 Thioredoxin Glutaredoxin PF00462.19 EGC37579.1 - 0.12 12.4 0.1 0.18 11.7 0.1 1.4 1 0 0 1 1 1 0 Glutaredoxin Myosin_head PF00063.16 EGC37580.1 - 2.8e-237 789.1 3.7 4.9e-237 788.3 2.6 1.4 1 1 0 1 1 1 1 Myosin head (motor domain) Myosin_TH1 PF06017.8 EGC37580.1 - 8.2e-52 175.4 3.1 1.7e-51 174.4 2.2 1.6 1 0 0 1 1 1 1 Myosin tail SH3_1 PF00018.23 EGC37580.1 - 3.2e-17 61.6 0.1 7.2e-17 60.5 0.1 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC37580.1 - 1.3e-13 50.2 0.0 3e-13 49.1 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC37580.1 - 3.6e-08 32.7 0.0 1e-07 31.3 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain AAA_22 PF13401.1 EGC37580.1 - 0.0029 17.7 0.2 0.014 15.5 0.0 2.2 3 0 0 3 3 2 1 AAA domain AAA_16 PF13191.1 EGC37580.1 - 0.0097 15.9 0.0 0.026 14.4 0.0 1.7 1 0 0 1 1 1 1 AAA ATPase domain Zeta_toxin PF06414.7 EGC37580.1 - 0.017 14.2 0.9 0.045 12.8 0.0 2.0 2 0 0 2 2 2 0 Zeta toxin AAA_17 PF13207.1 EGC37580.1 - 0.021 15.6 0.1 0.21 12.4 0.0 2.8 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGC37580.1 - 0.025 14.8 0.0 0.1 12.8 0.0 2.1 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGC37580.1 - 0.052 13.1 0.1 0.11 12.1 0.1 1.5 1 0 0 1 1 1 0 NACHT domain DUF258 PF03193.11 EGC37580.1 - 0.095 11.8 0.4 1.8 7.7 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function, DUF258 Hpr_kinase_C PF07475.7 EGC37580.1 - 0.11 11.8 0.3 3.3 6.9 0.0 2.9 2 1 1 3 3 3 0 HPr Serine kinase C-terminal domain AAA_19 PF13245.1 EGC37580.1 - 0.14 11.8 0.0 0.33 10.7 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain Ank_2 PF12796.2 EGC37581.1 - 4.8e-26 90.9 0.0 1.7e-18 66.7 0.0 1.7 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank_5 PF13857.1 EGC37581.1 - 4.7e-20 71.1 0.6 1.3e-10 41.1 0.0 2.8 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC37581.1 - 2.6e-19 67.9 0.0 3.5e-09 35.9 0.0 3.4 4 0 0 4 4 4 2 Ankyrin repeat Ank_4 PF13637.1 EGC37581.1 - 4e-17 62.2 0.0 6e-07 29.8 0.0 3.0 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC37581.1 - 8.6e-14 50.2 0.0 0.0001 22.1 0.0 3.7 4 0 0 4 4 4 2 Ankyrin repeat FRG PF08867.6 EGC37581.1 - 0.055 13.9 0.1 0.2 12.1 0.0 1.8 2 0 0 2 2 2 0 FRG domain Osteopontin PF00865.13 EGC37581.1 - 0.25 10.5 10.3 0.32 10.1 7.1 1.1 1 0 0 1 1 1 0 Osteopontin TPT PF03151.11 EGC37582.1 - 6.5e-09 35.6 13.1 6.5e-09 35.6 9.1 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family Gypsy PF07253.6 EGC37582.1 - 0.055 11.7 0.1 0.081 11.2 0.1 1.2 1 0 0 1 1 1 0 Gypsy protein Pox_I5 PF04713.7 EGC37582.1 - 0.092 12.4 6.0 0.05 13.3 1.0 2.8 2 1 1 3 3 3 0 Poxvirus protein I5 AAA PF00004.24 EGC37583.1 - 1.6e-07 31.6 0.1 3.8e-05 23.8 0.0 4.2 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC37583.1 - 0.00027 20.6 0.1 4 7.1 0.0 4.2 4 1 0 4 4 4 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC37583.1 - 0.024 14.6 0.0 20 5.1 0.1 3.5 2 1 0 2 2 2 0 AAA ATPase domain T2SE PF00437.15 EGC37583.1 - 0.038 12.9 0.0 0.09 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein IstB_IS21 PF01695.12 EGC37583.1 - 0.039 13.3 0.0 0.67 9.3 0.0 3.0 3 0 0 3 3 3 0 IstB-like ATP binding protein FAA_hydrolase PF01557.13 EGC37583.1 - 0.41 10.0 0.0 1 8.7 0.0 1.6 2 0 0 2 2 2 0 Fumarylacetoacetate (FAA) hydrolase family AAA_30 PF13604.1 EGC37583.1 - 0.78 9.2 0.0 9.9 5.6 0.0 2.2 2 0 0 2 2 2 0 AAA domain GalP_UDP_transf PF01087.17 EGC37585.1 - 0.075 13.0 0.0 0.094 12.7 0.0 1.1 1 0 0 1 1 1 0 Galactose-1-phosphate uridyl transferase, N-terminal domain Lip_prot_lig_C PF10437.4 EGC37585.1 - 0.14 11.8 1.4 1 9.1 0.2 2.3 1 1 1 2 2 2 0 Bacterial lipoate protein ligase C-terminus SPOB_a PF14689.1 EGC37585.1 - 0.27 10.8 2.5 0.55 9.8 1.8 1.6 1 0 0 1 1 1 0 Sensor_kinase_SpoOB-type, alpha-helical domain bZIP_1 PF00170.16 EGC37585.1 - 1.4 8.9 5.1 3 7.8 0.8 2.6 3 0 0 3 3 3 0 bZIP transcription factor AAA PF00004.24 EGC37587.1 - 9.4e-08 32.3 0.1 4.1e-05 23.7 0.0 4.3 3 0 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC37587.1 - 0.001 18.7 0.0 3.9 7.1 0.0 4.1 4 0 0 4 4 4 1 AAA domain (dynein-related subfamily) T2SE PF00437.15 EGC37587.1 - 0.036 12.9 0.0 0.088 11.6 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_16 PF13191.1 EGC37587.1 - 0.13 12.2 0.0 10 6.0 0.1 3.3 2 1 0 2 2 2 0 AAA ATPase domain AAA_30 PF13604.1 EGC37587.1 - 8.5 5.8 0.0 1.3e+02 2.0 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EGC37588.1 - 2.7e-124 414.8 1.0 3.2e-124 414.5 0.7 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC37588.1 - 3.9e-13 49.0 0.2 4.9e-09 35.6 0.0 2.4 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC37588.1 - 0.00034 19.8 2.2 0.096 11.8 0.0 2.6 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC37588.1 - 0.0035 17.2 0.0 0.49 10.3 0.0 2.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC37588.1 - 0.044 13.2 0.2 1.8 7.9 0.0 2.4 2 1 0 2 2 2 0 Elongation factor Tu GTP binding domain Miro PF08477.8 EGC37588.1 - 0.062 13.7 0.3 13 6.2 0.0 3.0 3 1 0 3 3 3 0 Miro-like protein Malic_M PF03949.10 EGC37588.1 - 0.065 12.7 0.1 0.18 11.3 0.0 1.6 1 1 1 2 2 2 0 Malic enzyme, NAD binding domain zf-RING_2 PF13639.1 EGC37589.1 - 4.9e-09 35.8 15.5 4.9e-09 35.8 10.7 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC37589.1 - 9.4e-06 25.6 10.9 9.4e-06 25.6 7.5 1.9 2 0 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC37589.1 - 4.1e-05 23.1 14.4 8.4e-05 22.1 10.0 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37589.1 - 0.00022 20.8 19.9 0.00022 20.8 13.8 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EGC37589.1 - 0.001 19.0 41.7 0.0014 18.5 28.9 1.2 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-C3HC4_2 PF13923.1 EGC37589.1 - 0.0011 18.9 18.2 0.0011 18.9 12.6 1.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37589.1 - 0.015 14.9 17.8 0.015 14.9 12.3 2.1 2 0 0 2 2 2 0 zinc-RING finger domain Med15 PF09606.5 EGC37589.1 - 0.036 12.2 39.4 0.047 11.9 27.3 1.3 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-RING_UBOX PF13445.1 EGC37589.1 - 0.055 13.1 10.3 0.31 10.7 7.2 2.3 1 1 0 1 1 1 0 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC37589.1 - 0.47 10.3 15.8 2.2 8.2 10.9 2.3 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF393 PF04134.7 EGC37589.1 - 1.3 10.1 0.0 1.3 10.1 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function, DUF393 zf-Apc11 PF12861.2 EGC37589.1 - 7.2 6.5 16.1 0.32 10.8 6.4 2.3 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Cytochrom_B558a PF05038.8 EGC37590.1 - 9e-13 48.2 10.1 2.5e-10 40.2 0.5 2.0 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit Auts2 PF15336.1 EGC37593.1 - 0.019 15.0 0.3 0.019 15.0 0.2 1.2 1 0 0 1 1 1 0 Autism susceptibility gene 2 protein Pkinase PF00069.20 EGC37594.1 - 4.4e-73 245.6 0.0 4.4e-73 245.6 0.0 2.9 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37594.1 - 1.3e-44 152.2 0.0 1.3e-44 152.2 0.0 2.2 2 0 0 2 2 2 1 Protein tyrosine kinase HEAT_2 PF13646.1 EGC37594.1 - 8.9e-09 35.5 0.0 1.3e-06 28.5 0.0 2.8 2 0 0 2 2 2 1 HEAT repeats HEAT PF02985.17 EGC37594.1 - 1.2e-08 34.3 0.0 0.02 14.9 0.0 4.6 4 0 0 4 4 4 2 HEAT repeat Kinase-like PF14531.1 EGC37594.1 - 2.5e-07 29.9 0.0 2.5e-07 29.9 0.0 2.3 2 0 0 2 2 2 1 Kinase-like HEAT_EZ PF13513.1 EGC37594.1 - 7.8e-05 23.0 0.0 1.6 9.3 0.0 4.5 4 0 0 4 4 4 1 HEAT-like repeat APH PF01636.18 EGC37594.1 - 0.021 14.5 1.9 0.031 14.0 0.0 2.1 2 0 0 2 2 2 0 Phosphotransferase enzyme family Coiled PF05710.7 EGC37595.1 - 0.014 15.8 2.4 0.014 15.8 1.7 1.1 1 0 0 1 1 1 0 Coiled coil Coatomer_WDAD PF04053.9 EGC37596.1 - 2e-123 412.4 2.6 4.8e-123 411.2 1.8 1.6 1 0 0 1 1 1 1 Coatomer WD associated region COPI_C PF06957.6 EGC37596.1 - 2.2e-115 385.6 0.0 3e-115 385.1 0.0 1.1 1 0 0 1 1 1 1 Coatomer (COPI) alpha subunit C-terminus WD40 PF00400.27 EGC37596.1 - 3.6e-55 181.9 7.5 6.4e-09 35.3 0.1 7.7 8 0 0 8 8 8 6 WD domain, G-beta repeat Nup160 PF11715.3 EGC37596.1 - 0.0008 17.6 1.0 0.065 11.3 0.0 3.2 2 1 1 3 3 3 1 Nucleoporin Nup120/160 TPR_2 PF07719.12 EGC37596.1 - 0.035 14.0 0.1 17 5.6 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37596.1 - 0.099 12.2 0.0 2.1 8.0 0.0 2.8 2 0 0 2 2 2 0 Tetratricopeptide repeat Sulfotransfer_1 PF00685.22 EGC37597.1 - 9.2e-20 71.0 1.5 7e-19 68.1 1.0 2.0 1 1 0 1 1 1 1 Sulfotransferase domain Sulfotransfer_3 PF13469.1 EGC37597.1 - 8.6e-06 26.7 0.0 0.00014 22.8 0.0 2.6 1 1 0 1 1 1 1 Sulfotransferase family Sulphotransf PF09037.5 EGC37597.1 - 0.049 13.1 0.0 0.76 9.2 0.0 2.4 3 0 0 3 3 3 0 Stf0 sulphotransferase SRP9-21 PF05486.7 EGC37598.1 - 5.6e-22 77.2 0.3 6.1e-22 77.1 0.2 1.0 1 0 0 1 1 1 1 Signal recognition particle 9 kDa protein (SRP9) Lipoprotein_21 PF14041.1 EGC37598.1 - 0.024 14.5 0.3 0.039 13.8 0.2 1.3 1 1 0 1 1 1 0 LppP/LprE lipoprotein DUF573 PF04504.9 EGC37598.1 - 0.16 12.2 1.9 0.17 12.1 1.3 1.1 1 0 0 1 1 1 0 Protein of unknown function, DUF573 U1snRNP70_N PF12220.3 EGC37600.1 - 2.1e-19 69.6 6.9 2.1e-19 69.6 4.8 3.9 3 0 0 3 3 3 1 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal RRM_1 PF00076.17 EGC37600.1 - 1.2e-18 66.4 0.1 2.2e-18 65.6 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37600.1 - 4.5e-13 48.9 0.0 7.4e-13 48.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37600.1 - 4.4e-11 42.4 0.0 7.9e-11 41.6 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGC37600.1 - 0.0026 16.3 52.9 0.0026 16.3 36.7 2.0 2 0 0 2 2 2 1 Microtubule-binding protein MIP-T3 WD40 PF00400.27 EGC37601.1 - 2.8e-48 160.1 31.2 2.6e-08 33.4 0.5 8.0 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box PF00646.28 EGC37601.1 - 2.8e-05 23.6 0.1 5.8e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 F-box domain Nup160 PF11715.3 EGC37601.1 - 4.7e-05 21.7 16.1 0.055 11.6 0.0 5.6 1 1 4 5 5 5 4 Nucleoporin Nup120/160 F-box-like PF12937.2 EGC37601.1 - 0.00012 21.6 0.2 0.00023 20.8 0.1 1.5 1 0 0 1 1 1 1 F-box-like IF4E PF01652.13 EGC37602.1 - 7e-49 165.5 0.4 9.6e-49 165.0 0.3 1.2 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E ORC6 PF05460.8 EGC37602.1 - 2.7 7.0 13.3 4 6.4 9.2 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) FH2 PF02181.18 EGC37603.1 - 4.4e-85 285.7 14.2 4.4e-85 285.7 9.8 2.9 2 0 0 2 2 2 1 Formin Homology 2 Domain FHA PF00498.21 EGC37603.1 - 7.2e-10 38.8 1.5 8.9e-06 25.7 0.0 3.5 3 0 0 3 3 3 2 FHA domain Drf_FH3 PF06367.11 EGC37603.1 - 1e-08 34.8 2.6 1e-08 34.8 1.8 4.6 5 0 0 5 5 5 2 Diaphanous FH3 Domain Ribosomal_L30 PF00327.15 EGC37603.1 - 0.11 12.1 1.0 0.33 10.5 0.0 2.3 2 0 0 2 2 2 0 Ribosomal protein L30p/L7e Herpes_U26 PF07402.6 EGC37603.1 - 0.21 10.8 1.3 0.34 10.1 0.9 1.2 1 0 0 1 1 1 0 Human herpesvirus U26 protein AIF_C PF14721.1 EGC37604.1 - 0.024 14.8 1.3 0.033 14.4 0.9 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PBP1_TM PF14812.1 EGC37604.1 - 0.097 12.9 4.4 0.31 11.3 2.9 1.8 1 1 1 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Neur PF00064.13 EGC37604.1 - 0.098 10.7 7.4 0.11 10.5 5.2 1.1 1 0 0 1 1 1 0 Neuraminidase Afi1 PF07792.7 EGC37604.1 - 0.97 9.4 13.6 1.3 9.0 9.4 1.1 1 0 0 1 1 1 0 Docking domain of Afi1 for Arf3 in vesicle trafficking DOT1 PF08123.8 EGC37605.1 - 9e-28 96.9 1.4 3e-27 95.2 0.0 2.8 2 0 0 2 2 2 1 Histone methylation protein DOT1 Methyltransf_18 PF12847.2 EGC37605.1 - 6.2e-09 36.4 0.1 4.3e-08 33.7 0.0 2.3 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC37605.1 - 0.00048 20.1 0.0 0.00091 19.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC37605.1 - 0.01 16.2 0.8 0.063 13.7 0.0 2.8 3 0 0 3 3 3 0 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37605.1 - 0.018 15.3 0.1 0.05 13.9 0.1 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC37605.1 - 0.035 13.8 0.3 0.11 12.1 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain ELMO_CED12 PF04727.8 EGC37607.1 - 3e-32 111.4 0.2 7.8e-32 110.1 0.1 1.8 1 0 0 1 1 1 1 ELMO/CED-12 family Peptidase_C1 PF00112.18 EGC37608.1 - 2e-42 145.5 0.4 2e-42 145.5 0.3 2.3 2 1 0 2 2 2 1 Papain family cysteine protease CBM49 PF09478.5 EGC37608.1 - 9.3e-18 64.1 6.1 2.5e-17 62.7 4.2 1.7 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.7 EGC37608.1 - 1.3e-11 44.5 10.0 1.4e-11 44.4 5.6 2.2 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) zf-RING_2 PF13639.1 EGC37609.1 - 7.4e-11 41.6 13.1 1.6e-10 40.6 9.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC37609.1 - 5.4e-09 35.5 10.8 1.2e-08 34.5 7.5 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37609.1 - 3e-07 29.9 16.9 9e-07 28.4 11.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37609.1 - 4.5e-07 29.8 11.4 1.4e-06 28.3 7.9 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC37609.1 - 2.9e-06 27.1 14.9 7.7e-06 25.8 10.3 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37609.1 - 8.3e-06 25.4 14.8 2.3e-05 23.9 10.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC37609.1 - 0.001 18.8 13.4 0.0033 17.2 9.3 1.9 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC37609.1 - 0.0015 18.0 13.3 0.0038 16.7 9.2 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Baculo_RING PF05883.6 EGC37609.1 - 0.01 15.6 7.3 0.01 15.6 5.1 2.4 3 0 0 3 3 3 0 Baculovirus U-box/Ring-like domain zf-HC5HC2H PF13771.1 EGC37609.1 - 0.027 14.5 9.1 0.12 12.4 6.3 2.2 1 0 0 1 1 1 0 PHD-like zinc-binding domain zf-RING_6 PF14835.1 EGC37609.1 - 0.24 11.2 3.6 0.52 10.1 2.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein DUF1272 PF06906.6 EGC37609.1 - 0.53 10.1 10.0 1.4 8.7 6.9 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 EGC37609.1 - 6.8 6.4 17.3 0.071 12.8 5.6 2.6 2 0 0 2 2 2 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC37609.1 - 7.5 6.4 14.2 0.39 10.5 5.5 2.2 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CALCOCO1 PF07888.6 EGC37610.1 - 0.00037 18.9 6.2 0.00046 18.6 4.3 1.1 1 0 0 1 1 1 1 Calcium binding and coiled-coil domain (CALCOCO1) like Tropomyosin_1 PF12718.2 EGC37610.1 - 0.00097 19.0 15.1 0.0021 17.9 10.5 1.5 1 0 0 1 1 1 1 Tropomyosin like IncA PF04156.9 EGC37610.1 - 0.004 16.7 7.8 0.0056 16.3 5.4 1.2 1 0 0 1 1 1 1 IncA protein Atg14 PF10186.4 EGC37610.1 - 0.006 15.5 8.4 0.01 14.8 5.8 1.3 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 Myosin_tail_1 PF01576.14 EGC37610.1 - 0.0078 13.9 13.5 0.012 13.4 9.4 1.1 1 0 0 1 1 1 1 Myosin tail Prefoldin PF02996.12 EGC37610.1 - 0.0091 15.6 0.4 0.0091 15.6 0.3 2.5 2 0 0 2 2 2 1 Prefoldin subunit ATG16 PF08614.6 EGC37610.1 - 0.012 15.4 13.6 0.029 14.1 9.4 1.7 1 0 0 1 1 1 0 Autophagy protein 16 (ATG16) DUF4472 PF14739.1 EGC37610.1 - 0.014 15.8 14.6 0.055 13.9 9.1 2.5 2 1 0 2 2 1 0 Domain of unknown function (DUF4472) DUF3450 PF11932.3 EGC37610.1 - 0.021 14.1 4.7 0.032 13.5 3.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) ADIP PF11559.3 EGC37610.1 - 0.022 14.6 12.1 0.064 13.1 8.4 1.8 1 0 0 1 1 1 0 Afadin- and alpha -actinin-Binding GrpE PF01025.14 EGC37610.1 - 0.071 12.6 11.9 0.027 14.0 5.2 2.1 1 1 1 2 2 2 0 GrpE DivIC PF04977.10 EGC37610.1 - 0.075 12.5 17.9 1 8.8 1.9 3.3 1 1 1 2 2 2 0 Septum formation initiator Enolase_N PF03952.11 EGC37610.1 - 0.08 12.8 0.2 0.18 11.7 0.1 1.6 1 0 0 1 1 1 0 Enolase, N-terminal domain TMF_DNA_bd PF12329.3 EGC37610.1 - 0.082 12.7 22.5 0.056 13.2 7.4 2.7 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding AKNA PF12443.3 EGC37610.1 - 0.15 12.1 6.4 0.58 10.2 2.5 2.6 2 1 1 3 3 2 0 AT-hook-containing transcription factor DUF2205 PF10224.4 EGC37610.1 - 0.37 10.3 15.8 9.2 5.9 2.2 3.5 1 1 2 3 3 3 0 Predicted coiled-coil protein (DUF2205) Nup54 PF13874.1 EGC37610.1 - 1.1 8.9 9.1 2.2 7.9 0.8 2.3 1 1 1 2 2 2 0 Nucleoporin complex subunit 54 DUF16 PF01519.11 EGC37610.1 - 1.1 9.5 10.6 4.2 7.6 7.3 2.1 1 1 0 1 1 1 0 Protein of unknown function DUF16 DUF763 PF05559.6 EGC37610.1 - 1.2 8.0 5.9 1.3 7.9 1.9 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF763) bZIP_1 PF00170.16 EGC37610.1 - 1.5 8.8 17.9 0.11 12.4 6.5 2.7 1 1 2 3 3 3 0 bZIP transcription factor Macoilin PF09726.4 EGC37610.1 - 1.5 7.0 15.1 0.75 8.0 9.1 1.4 2 0 0 2 2 2 0 Transmembrane protein V_ATPase_I PF01496.14 EGC37610.1 - 2 6.2 7.5 2.2 6.0 5.2 1.2 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Secretin_N_2 PF07655.8 EGC37610.1 - 2.4 8.5 9.4 6.5 7.2 6.5 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Lge1 PF11488.3 EGC37610.1 - 3.6 7.8 13.9 0.25 11.5 2.1 2.9 2 1 1 3 3 3 0 Transcriptional regulatory protein LGE1 DUF724 PF05266.9 EGC37610.1 - 4.2 6.9 11.5 9.6 5.7 7.6 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF724) Uds1 PF15456.1 EGC37610.1 - 4.2 7.3 8.9 24 4.9 6.2 2.1 1 1 0 1 1 1 0 Up-regulated During Septation RasGEF PF00617.14 EGC37612.1 - 1.5e-53 181.3 1.5 4e-53 179.9 0.0 2.6 3 0 0 3 3 3 1 RasGEF domain LRR_4 PF12799.2 EGC37612.1 - 6.2e-34 115.0 72.9 2.1e-09 36.7 1.4 10.3 6 2 4 10 10 10 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC37612.1 - 6e-28 96.3 57.8 8.2e-12 44.6 3.9 7.9 4 1 2 7 7 7 6 Leucine rich repeat LRR_1 PF00560.28 EGC37612.1 - 3.2e-16 56.8 51.7 0.003 17.3 0.1 15.0 15 0 0 15 15 15 6 Leucine Rich Repeat RasGEF_N PF00618.15 EGC37612.1 - 9.8e-12 44.8 0.4 9.8e-12 44.8 0.3 3.0 2 0 0 2 2 2 1 RasGEF N-terminal motif LRR_7 PF13504.1 EGC37612.1 - 5.7e-11 40.7 46.7 0.16 12.2 0.1 13.9 14 0 0 14 14 14 6 Leucine rich repeat Drf_GBD PF06371.8 EGC37612.1 - 1.1e-10 41.1 0.2 6.6e-10 38.6 0.1 2.3 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain FERM_N PF09379.5 EGC37612.1 - 2.2e-06 27.5 0.1 0.36 10.8 0.0 3.6 3 0 0 3 3 3 2 FERM N-terminal domain LRR_6 PF13516.1 EGC37612.1 - 0.022 14.7 51.4 0.26 11.4 0.5 12.5 13 0 0 13 13 13 0 Leucine Rich repeat GED PF02212.13 EGC37612.1 - 0.081 12.8 4.0 6.5 6.7 0.1 3.0 2 0 0 2 2 2 0 Dynamin GTPase effector domain DHO_dh PF01180.16 EGC37613.1 - 2.3e-34 118.7 0.0 1.2e-33 116.3 0.0 2.0 2 0 0 2 2 2 1 Dihydroorotate dehydrogenase Fer4_21 PF14697.1 EGC37613.1 - 3.9e-23 81.0 12.1 3.9e-23 81.0 8.4 2.7 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_20 PF14691.1 EGC37613.1 - 5e-11 42.1 0.0 5e-11 42.1 0.0 2.6 3 0 0 3 3 2 1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster Fer4_10 PF13237.1 EGC37613.1 - 2.9e-07 30.1 9.9 2.9e-07 30.1 6.9 2.7 2 1 1 3 3 3 2 4Fe-4S dicluster domain Dus PF01207.12 EGC37613.1 - 3.5e-07 29.3 0.2 1.5e-06 27.2 0.1 1.9 2 0 0 2 2 2 1 Dihydrouridine synthase (Dus) Fer4_7 PF12838.2 EGC37613.1 - 3.6e-07 30.4 8.7 3.6e-07 30.4 6.0 2.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4 PF00037.22 EGC37613.1 - 4e-07 29.3 21.6 0.0018 17.8 2.1 3.9 3 0 0 3 3 3 2 4Fe-4S binding domain NAD_binding_8 PF13450.1 EGC37613.1 - 8.8e-06 25.6 0.0 2.4e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain Pyr_redox_3 PF13738.1 EGC37613.1 - 3.4e-05 24.0 0.0 0.22 11.5 0.0 3.8 4 0 0 4 4 4 1 Pyridine nucleotide-disulphide oxidoreductase Fer4_9 PF13187.1 EGC37613.1 - 5.6e-05 23.3 12.2 5.6e-05 23.3 8.4 2.9 3 1 0 3 3 2 1 4Fe-4S dicluster domain Fer4_6 PF12837.2 EGC37613.1 - 7.5e-05 22.4 3.1 7.5e-05 22.4 2.1 3.3 3 0 0 3 3 2 2 4Fe-4S binding domain Fer4_2 PF12797.2 EGC37613.1 - 0.00023 20.9 20.5 0.0051 16.6 1.4 3.7 3 0 0 3 3 3 2 4Fe-4S binding domain Pyr_redox PF00070.22 EGC37613.1 - 0.00033 20.9 0.0 1.6 9.1 0.0 2.9 2 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC37613.1 - 0.00055 19.8 0.1 1.3 8.9 0.0 2.9 3 1 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase Fer4_8 PF13183.1 EGC37613.1 - 0.0019 18.2 8.8 0.0019 18.2 6.1 2.7 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_13 PF13370.1 EGC37613.1 - 0.0054 17.1 12.3 0.023 15.0 2.0 3.1 2 0 0 2 2 2 1 4Fe-4S single cluster domain Fer4_15 PF13459.1 EGC37613.1 - 0.006 17.1 11.9 0.066 13.7 0.7 3.5 3 0 0 3 3 2 2 4Fe-4S single cluster domain Fer4_18 PF13746.1 EGC37613.1 - 0.011 16.1 9.2 1.4 9.3 0.5 3.6 3 0 0 3 3 3 0 4Fe-4S dicluster domain Fer4_4 PF12800.2 EGC37613.1 - 0.056 13.8 25.1 0.062 13.6 1.9 3.8 3 0 0 3 3 2 0 4Fe-4S binding domain Fer4_17 PF13534.1 EGC37613.1 - 0.14 12.5 14.4 0.17 12.2 0.1 3.1 3 0 0 3 3 2 0 4Fe-4S dicluster domain PcrB PF01884.12 EGC37613.1 - 0.2 10.8 0.0 9.4 5.4 0.0 2.2 2 0 0 2 2 2 0 PcrB family Fer4_16 PF13484.1 EGC37613.1 - 2.2 9.0 16.9 0.75 10.5 0.6 3.7 2 1 2 4 4 4 0 4Fe-4S double cluster binding domain COG4 PF08318.7 EGC37614.1 - 6e-31 107.4 28.4 6e-31 107.4 19.7 3.6 3 1 0 3 3 3 1 COG4 transport protein DUF948 PF06103.6 EGC37614.1 - 0.29 11.0 4.7 0.72 9.7 0.3 3.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF948) DENN PF02141.16 EGC37615.1 - 1.4e-28 99.8 4.3 3e-26 92.2 0.3 3.0 3 0 0 3 3 3 2 DENN (AEX-3) domain uDENN PF03456.13 EGC37615.1 - 6.8e-06 25.9 1.4 4.8e-05 23.2 1.0 2.5 1 1 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGC37615.1 - 0.001 19.1 0.8 0.001 19.1 0.6 1.9 2 0 0 2 2 2 1 dDENN domain Peptidase_M20 PF01546.23 EGC37616.1 - 2.5e-23 82.5 0.0 3.4e-23 82.1 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC37616.1 - 4.8e-16 58.4 0.0 9.5e-16 57.5 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain Inhibitor_I71 PF12628.2 EGC37617.1 - 0.26 10.9 6.5 1.4 8.6 3.8 2.1 2 0 0 2 2 2 0 Falstatin, cysteine peptidase inhibitor Plant_all_beta PF10532.4 EGC37617.1 - 3.1 7.8 11.5 16 5.6 0.1 2.3 2 0 0 2 2 2 0 Plant specific N-all beta domain Fcf1 PF04900.7 EGC37618.1 - 3.6e-37 126.4 4.2 5.1e-37 126.0 0.4 2.0 2 0 0 2 2 2 1 Fcf1 THOC7 PF05615.8 EGC37618.1 - 0.047 13.9 0.7 0.084 13.1 0.5 1.3 1 0 0 1 1 1 0 Tho complex subunit 7 Cpn60_TCP1 PF00118.19 EGC37619.1 - 6.2e-127 424.1 1.2 1.1e-126 423.2 0.8 1.4 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family RRM_1 PF00076.17 EGC37620.1 - 4.3e-29 99.9 2.7 1.7e-18 65.9 0.0 3.4 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37620.1 - 2.1e-21 75.6 0.5 1.7e-13 50.3 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37620.1 - 6.4e-10 38.7 0.1 2e-06 27.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) MIP-T3 PF10243.4 EGC37620.1 - 0.00026 19.6 42.8 0.0007 18.1 29.7 1.7 1 0 0 1 1 1 1 Microtubule-binding protein MIP-T3 Suf PF05843.9 EGC37620.1 - 0.0011 18.7 30.0 0.0011 18.7 20.8 6.2 3 2 3 6 6 6 3 Suppressor of forked protein (Suf) ARD PF03079.9 EGC37621.1 - 2.9e-46 157.2 1.5 3.4e-46 157.0 1.0 1.0 1 0 0 1 1 1 1 ARD/ARD' family Cupin_2 PF07883.6 EGC37621.1 - 3.5e-10 39.2 0.0 5.3e-10 38.6 0.0 1.3 1 0 0 1 1 1 1 Cupin domain AraC_binding PF02311.14 EGC37621.1 - 1.2e-05 25.0 0.0 1.9e-05 24.3 0.0 1.3 1 0 0 1 1 1 1 AraC-like ligand binding domain Cupin_1 PF00190.17 EGC37621.1 - 0.001 18.4 0.0 0.0016 17.8 0.0 1.3 1 0 0 1 1 1 1 Cupin Ank_2 PF12796.2 EGC37622.1 - 0.0031 17.8 0.1 0.04 14.2 0.0 2.8 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) XPG_N PF00752.12 EGC37623.1 - 1.1e-26 93.0 0.0 1.2e-26 92.9 0.0 1.0 1 0 0 1 1 1 1 XPG N-terminal domain MMR_HSR1 PF01926.18 EGC37624.1 - 9.1e-15 54.6 0.1 8.7e-13 48.2 0.0 3.1 2 0 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC37624.1 - 8e-05 21.9 1.0 0.00031 20.0 0.0 2.4 3 0 0 3 3 3 1 Ferrous iron transport protein B DUF258 PF03193.11 EGC37624.1 - 0.0042 16.2 0.0 0.012 14.7 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC37624.1 - 0.18 12.3 6.0 0.23 11.9 0.0 3.4 3 0 0 3 3 3 0 Miro-like protein PB1 PF00564.19 EGC37625.1 - 1.2e-18 66.4 0.1 2.5e-18 65.5 0.1 1.6 1 0 0 1 1 1 1 PB1 domain ZZ PF00569.12 EGC37625.1 - 2.1e-10 39.9 8.4 3.6e-10 39.2 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type UBA_3 PF09288.5 EGC37625.1 - 0.029 13.9 0.0 0.099 12.2 0.0 1.9 1 0 0 1 1 1 0 Fungal ubiquitin-associated domain GST_N_2 PF13409.1 EGC37626.1 - 1.6e-14 53.6 0.0 3e-14 52.7 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC37626.1 - 1.7e-10 40.6 0.0 2.8e-10 39.9 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC37626.1 - 1.7e-05 24.6 0.3 3.9e-05 23.5 0.2 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC37626.1 - 2e-05 24.9 0.0 3.5e-05 24.2 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC37626.1 - 0.00011 22.3 0.0 0.0022 18.1 0.0 2.4 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain VP9 PF09625.5 EGC37626.1 - 0.12 12.2 0.2 1 9.2 0.0 2.3 2 0 0 2 2 2 0 VP9 protein Apc3 PF12895.2 EGC37627.1 - 4.1e-09 36.4 3.3 3.6e-06 27.0 0.2 3.0 3 0 0 3 3 3 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_19 PF14559.1 EGC37627.1 - 7.7e-09 35.7 0.1 0.45 10.8 0.0 3.6 4 0 0 4 4 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC37627.1 - 1.8e-07 30.7 5.5 0.00037 20.0 0.0 3.2 3 1 1 4 4 4 2 TPR repeat TPR_2 PF07719.12 EGC37627.1 - 1.2e-05 24.8 0.4 0.36 10.8 0.0 4.2 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37627.1 - 0.00011 22.7 0.0 0.097 13.3 0.0 2.8 2 1 0 3 3 2 1 Tetratricopeptide repeat TPR_20 PF14561.1 EGC37627.1 - 0.0013 18.8 0.0 11 6.1 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37627.1 - 0.0051 16.4 4.4 0.3 10.9 0.0 3.2 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37627.1 - 0.0071 16.2 0.3 4.2 7.3 0.0 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC37627.1 - 0.0087 16.6 0.0 4.4 8.2 0.0 4.5 3 1 2 5 5 5 1 Tetratricopeptide repeat NARP1 PF12569.3 EGC37627.1 - 0.022 13.5 0.4 1 7.9 0.0 2.4 1 1 1 2 2 2 0 NMDA receptor-regulated protein 1 TPR_9 PF13371.1 EGC37627.1 - 0.14 12.0 0.0 0.46 10.3 0.0 1.8 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC37627.1 - 0.15 12.5 3.7 37 5.0 0.0 4.6 6 0 0 6 6 5 0 Tetratricopeptide repeat Pol_alpha_B_N PF08418.5 EGC37627.1 - 0.97 8.9 15.4 1.8 8.0 10.7 1.3 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal Macoilin PF09726.4 EGC37627.1 - 2 6.6 8.5 2.8 6.0 5.9 1.1 1 0 0 1 1 1 0 Transmembrane protein Lipase_3 PF01764.20 EGC37629.1 - 9e-32 109.6 0.0 1.3e-31 109.1 0.0 1.2 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGC37629.1 - 0.00072 19.3 0.0 0.00095 18.9 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF2974 PF11187.3 EGC37629.1 - 0.0025 17.2 0.1 0.006 15.9 0.0 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EGC37629.1 - 0.02 14.8 0.0 0.024 14.5 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family DUF676 PF05057.9 EGC37629.1 - 0.036 13.3 0.0 0.058 12.6 0.0 1.3 1 0 0 1 1 1 0 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGC37629.1 - 0.047 13.2 0.0 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 PGAP1-like protein ATE_C PF04377.10 EGC37630.1 - 1.3e-48 164.3 3.1 3.5e-48 162.8 2.1 1.8 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, C terminus ATE_N PF04376.8 EGC37630.1 - 3.6e-24 84.3 0.8 1.2e-23 82.6 0.5 1.9 1 0 0 1 1 1 1 Arginine-tRNA-protein transferase, N terminus MGC-24 PF05283.6 EGC37630.1 - 6.2 6.5 9.4 2.9 7.6 1.9 2.5 2 0 0 2 2 2 0 Multi-glycosylated core protein 24 (MGC-24) Lustrin_cystein PF14625.1 EGC37631.1 - 0.028 14.4 9.0 0.15 12.1 2.1 2.9 1 1 1 2 2 2 0 Lustrin, cysteine-rich repeated domain Dickkopf_N PF04706.7 EGC37631.1 - 0.046 13.8 4.9 0.046 13.8 3.4 3.0 3 1 1 4 4 4 0 Dickkopf N-terminal cysteine-rich region Nodulin_late PF07127.6 EGC37631.1 - 0.071 13.2 0.5 0.071 13.2 0.4 3.6 3 1 1 4 4 4 0 Late nodulin protein Kelch_4 PF13418.1 EGC37632.1 - 1.4e-42 143.1 13.8 2.9e-09 36.5 0.0 6.5 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC37632.1 - 3.6e-33 112.9 11.2 1.1e-09 38.1 0.0 7.5 8 0 0 8 8 8 4 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC37632.1 - 2e-30 104.2 16.3 4.7e-09 36.0 0.1 6.7 6 0 0 6 6 6 6 Kelch motif Kelch_6 PF13964.1 EGC37632.1 - 2.3e-24 84.5 21.0 6e-07 29.3 0.4 6.5 5 1 1 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EGC37632.1 - 1.8e-23 81.8 12.5 1.7e-07 30.6 0.5 5.6 5 0 0 5 5 5 4 Kelch motif Kelch_2 PF07646.10 EGC37632.1 - 1.4e-21 75.3 12.8 9.9e-06 25.1 0.2 6.3 6 0 0 6 6 6 4 Kelch motif zf-C3HC4_3 PF13920.1 EGC37632.1 - 2.9e-12 46.0 9.2 5.1e-12 45.2 6.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37632.1 - 0.00023 21.1 12.4 0.00046 20.1 8.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37632.1 - 0.011 15.3 10.2 0.023 14.4 7.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain DENN PF02141.16 EGC37634.1 - 2.3e-45 154.6 6.8 4.2e-45 153.7 3.6 2.4 2 0 0 2 2 2 1 DENN (AEX-3) domain LIM PF00412.17 EGC37634.1 - 8.9e-13 48.1 40.4 1.1e-05 25.3 8.9 3.8 3 0 0 3 3 3 3 LIM domain uDENN PF03456.13 EGC37634.1 - 1.2e-10 41.1 0.0 4.2e-10 39.4 0.0 2.0 1 0 0 1 1 1 1 uDENN domain dDENN PF03455.14 EGC37634.1 - 5.2e-07 29.6 1.7 7.2e-07 29.1 0.1 2.1 2 0 0 2 2 2 1 dDENN domain Zip PF02535.17 EGC37634.1 - 7.3 5.5 20.7 19 4.1 14.3 1.7 1 0 0 1 1 1 0 ZIP Zinc transporter DUF843 PF05814.6 EGC37635.1 - 0.1 12.3 0.2 0.23 11.2 0.1 1.5 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) TetR_C_4 PF08359.6 EGC37636.1 - 0.086 12.7 2.7 0.17 11.7 0.1 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region zf-RING_2 PF13639.1 EGC37637.1 - 5.9e-10 38.8 9.3 1.1e-09 37.9 6.4 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC37637.1 - 1.3e-08 34.3 11.5 3.7e-08 32.8 8.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Methyltransf_2 PF00891.13 EGC37637.1 - 7.7e-08 31.8 0.2 1.2e-07 31.2 0.1 1.2 1 0 0 1 1 1 1 O-methyltransferase zf-rbx1 PF12678.2 EGC37637.1 - 1.3e-07 31.5 5.2 3.6e-07 30.2 3.6 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC37637.1 - 1.2e-06 28.1 6.2 1.9e-06 27.4 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37637.1 - 3e-06 26.8 10.2 5.8e-06 25.9 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC37637.1 - 6e-06 26.1 9.9 1.1e-05 25.3 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC37637.1 - 0.00076 19.3 9.1 0.0018 18.0 6.3 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC37637.1 - 0.0038 16.7 9.1 0.0076 15.8 6.3 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC37637.1 - 0.0041 16.9 2.7 0.0087 15.8 1.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.1 EGC37637.1 - 0.016 14.9 0.9 0.016 14.9 0.7 1.9 2 0 0 2 2 1 0 Zinc-binding RING-finger zf-MIZ PF02891.15 EGC37637.1 - 0.031 13.7 8.3 0.058 12.9 5.8 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger FYDLN_acid PF09538.5 EGC37637.1 - 0.29 11.7 0.1 0.29 11.7 0.0 3.7 4 1 0 4 4 4 0 Protein of unknown function (FYDLN_acid) zf-RING_UBOX PF13445.1 EGC37637.1 - 0.31 10.7 5.4 0.85 9.3 3.8 1.8 1 0 0 1 1 1 0 RING-type zinc-finger Methyltransf_2 PF00891.13 EGC37638.1 - 1.6e-05 24.2 0.0 0.069 12.3 0.1 2.1 1 1 1 2 2 2 2 O-methyltransferase NmrA PF05368.8 EGC37639.1 - 6.5e-58 195.7 0.0 8e-58 195.4 0.0 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC37639.1 - 3e-11 43.6 0.0 4.5e-11 43.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC37639.1 - 1.1e-05 24.3 0.1 3.2e-05 22.7 0.0 1.8 2 0 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC37639.1 - 4.8e-05 22.8 0.0 8e-05 22.1 0.0 1.4 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family F420_oxidored PF03807.12 EGC37639.1 - 0.031 14.7 0.0 0.052 13.9 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent dDENN PF03455.14 EGC37639.1 - 0.062 13.3 1.8 0.11 12.5 0.3 2.0 2 0 0 2 2 2 0 dDENN domain adh_short PF00106.20 EGC37639.1 - 0.068 13.0 0.0 0.1 12.5 0.0 1.3 1 0 0 1 1 1 0 short chain dehydrogenase IlvN PF07991.7 EGC37639.1 - 0.081 12.2 0.1 0.2 11.0 0.0 1.6 1 1 0 1 1 1 0 Acetohydroxy acid isomeroreductase, catalytic domain HrcA_DNA-bdg PF03444.10 EGC37640.1 - 0.076 12.4 1.5 0.22 11.0 1.0 1.7 1 0 0 1 1 1 0 Winged helix-turn-helix transcription repressor, HrcA DNA-binding DUF2681 PF10883.3 EGC37640.1 - 1.2 9.3 6.4 13 6.1 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF2681) DUF365 PF04033.7 EGC37641.1 - 0.011 15.7 0.8 0.013 15.5 0.5 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF365) HTH_17 PF12728.2 EGC37641.1 - 0.072 13.3 0.1 0.1 12.8 0.1 1.2 1 0 0 1 1 1 0 Helix-turn-helix domain Nol1_Nop2_Fmu PF01189.12 EGC37643.1 - 1.5e-27 96.7 0.0 6.3e-13 48.7 0.0 2.1 1 1 1 2 2 2 2 NOL1/NOP2/sun family Methyltransf_31 PF13847.1 EGC37643.1 - 1.9e-08 34.0 4.8 5.9e-08 32.4 0.6 2.7 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC37643.1 - 1.1e-05 24.6 0.0 5.4e-05 22.4 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGC37643.1 - 1.6e-05 25.4 0.0 0.00021 21.8 0.0 2.4 1 1 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC37643.1 - 0.0001 21.9 0.0 0.00026 20.5 0.0 1.7 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_25 PF13649.1 EGC37643.1 - 0.0002 21.6 0.0 0.00049 20.4 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGC37643.1 - 0.00037 20.5 0.3 0.00081 19.4 0.2 1.7 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EGC37643.1 - 0.00044 20.2 0.0 0.0035 17.3 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Mem_trans PF03547.13 EGC37643.1 - 0.038 12.2 2.9 0.059 11.6 2.0 1.4 1 0 0 1 1 1 0 Membrane transport protein MTS PF05175.9 EGC37643.1 - 0.06 12.7 0.0 0.13 11.6 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_23 PF13489.1 EGC37643.1 - 0.064 12.9 0.0 0.28 10.8 0.0 1.9 2 0 0 2 2 2 0 Methyltransferase domain CDC45 PF02724.9 EGC37643.1 - 5 5.0 17.0 0.063 11.3 4.9 2.1 2 0 0 2 2 2 0 CDC45-like protein FUSC_2 PF13515.1 EGC37646.1 - 6.5e-13 48.7 39.3 1.6e-10 40.9 12.9 2.9 2 1 0 2 2 2 2 Fusaric acid resistance protein-like FNIP PF05725.7 EGC37647.1 - 5.8e-19 67.7 31.7 5.5e-09 35.8 2.7 4.0 3 1 1 4 4 4 4 FNIP Repeat Arm PF00514.18 EGC37648.1 - 1.7e-40 135.4 15.5 1.3e-06 28.0 0.0 12.0 12 0 0 12 12 12 9 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC37648.1 - 1.9e-25 88.9 0.0 3.3e-05 24.0 0.0 8.4 2 2 7 9 9 9 7 HEAT repeats HEAT PF02985.17 EGC37648.1 - 7.5e-16 56.7 21.2 0.006 16.5 0.1 10.6 12 0 0 12 12 11 4 HEAT repeat HEAT_EZ PF13513.1 EGC37648.1 - 1.7e-08 34.7 2.5 1.8 9.1 0.0 8.3 8 1 3 11 11 10 2 HEAT-like repeat RICTOR_V PF14668.1 EGC37648.1 - 6.3e-06 26.0 2.2 1.2 9.0 0.0 4.7 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Vac14_Fab1_bd PF12755.2 EGC37648.1 - 1.2e-05 25.5 7.0 0.26 11.6 0.1 4.5 4 1 0 5 5 4 2 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EGC37648.1 - 8.6e-05 22.4 8.2 3.3 7.6 0.1 5.6 3 2 3 6 6 6 2 V-ATPase subunit H Ric8 PF10165.4 EGC37648.1 - 0.00091 18.1 4.1 1.4 7.6 0.5 4.5 2 1 0 3 3 3 1 Guanine nucleotide exchange factor synembryn DUF2435 PF10363.4 EGC37648.1 - 0.0043 16.9 0.9 0.78 9.6 0.0 4.0 2 1 1 3 3 3 1 Protein of unknown function (DUF2435) Atx10homo_assoc PF09759.4 EGC37648.1 - 0.0044 16.7 11.5 4.1 7.2 0.1 5.5 5 1 1 6 6 6 1 Spinocerebellar ataxia type 10 protein domain DUF3361 PF11841.3 EGC37648.1 - 0.027 14.2 9.5 7.2 6.3 0.1 5.0 2 1 2 5 5 5 0 Domain of unknown function (DUF3361) Aconitase_B_N PF11791.3 EGC37648.1 - 0.066 13.0 0.7 18 5.1 0.0 4.0 4 0 0 4 4 4 0 Aconitate B N-terminal domain IBN_N PF03810.14 EGC37648.1 - 0.11 12.4 5.2 7.1 6.6 0.1 4.7 4 0 0 4 4 4 0 Importin-beta N-terminal domain DUF1981 PF09324.5 EGC37648.1 - 0.12 11.9 3.2 6.1 6.4 0.1 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF1981) DUF2454 PF10521.4 EGC37648.1 - 0.74 8.7 8.7 0.93 8.4 0.2 4.1 3 2 1 4 4 4 0 Protein of unknown function (DUF2454) Ded_cyto PF06920.8 EGC37649.1 - 7.9e-53 178.3 4.7 7.9e-53 178.3 3.3 2.4 3 0 0 3 3 3 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC37649.1 - 5.1e-24 84.9 18.6 5e-21 75.1 1.7 3.7 4 0 0 4 4 4 2 C2 domain in Dock180 and Zizimin proteins DUF3385 PF11865.3 EGC37649.1 - 0.0075 16.2 1.2 0.0075 16.2 0.8 2.5 2 0 0 2 2 2 1 Domain of unknown function (DUF3385) CENP-H PF05837.7 EGC37650.1 - 8.2e-06 25.9 6.0 8.2e-06 25.9 4.1 3.5 1 1 1 3 3 3 1 Centromere protein H (CENP-H) MRP-S26 PF14943.1 EGC37650.1 - 0.00081 18.9 7.7 0.00081 18.9 5.4 2.6 1 1 1 2 2 2 1 Mitochondrial ribosome subunit S26 YejG PF13989.1 EGC37650.1 - 0.029 14.4 5.3 0.99 9.4 0.2 2.9 2 1 0 2 2 2 0 YejG-like protein SapB_2 PF03489.12 EGC37651.1 - 9.1e-18 63.9 5.3 1.8e-08 34.2 0.1 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC37651.1 - 9.9e-17 60.3 5.0 1.1e-08 34.6 0.3 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 1 NB PF04159.8 EGC37651.1 - 0.0071 16.0 0.7 0.0071 16.0 0.5 2.3 2 1 0 2 2 2 1 NB glycoprotein DUF3456 PF11938.3 EGC37651.1 - 0.12 12.3 4.6 13 5.7 0.1 3.4 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP MFS_2 PF13347.1 EGC37652.1 - 0.00013 20.5 0.9 0.00013 20.5 0.6 3.0 4 0 0 4 4 4 2 MFS/sugar transport protein GNAT_acetyltr_2 PF13718.1 EGC37654.1 - 4.4e-80 267.6 0.0 7.6e-80 266.8 0.0 1.4 1 0 0 1 1 1 1 GNAT acetyltransferase 2 Helicase_RecD PF05127.9 EGC37654.1 - 1.6e-63 213.4 0.0 6.7e-63 211.5 0.0 2.1 2 0 0 2 2 2 1 Helicase DUF1726 PF08351.6 EGC37654.1 - 3.2e-38 129.2 0.9 1.3e-37 127.3 0.1 2.4 2 0 0 2 2 2 1 Domain of unknown function (DUF1726) tRNA_bind_2 PF13725.1 EGC37654.1 - 1.4e-29 102.1 1.6 4.3e-29 100.5 1.1 1.9 1 0 0 1 1 1 1 Possible tRNA binding domain zf-C3HC4_3 PF13920.1 EGC37654.1 - 8.9e-12 44.4 10.8 1.7e-11 43.6 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37654.1 - 0.00023 21.0 13.0 0.00061 19.7 9.0 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Acetyltransf_7 PF13508.1 EGC37654.1 - 0.00027 21.0 0.0 0.00083 19.4 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain zf-RING_5 PF14634.1 EGC37654.1 - 0.011 15.5 10.9 0.028 14.1 7.5 1.7 1 0 0 1 1 1 0 zinc-RING finger domain Acetyltransf_1 PF00583.19 EGC37654.1 - 0.021 14.8 0.0 0.054 13.5 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family zf-RING_2 PF13639.1 EGC37654.1 - 0.32 10.8 10.5 0.83 9.5 7.3 1.8 1 0 0 1 1 1 0 Ring finger domain Prok-RING_4 PF14447.1 EGC37654.1 - 0.87 9.1 6.8 1.9 8.0 4.7 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 WD40 PF00400.27 EGC37655.1 - 7.5e-34 114.3 10.4 1.5e-08 34.2 0.1 6.9 7 0 0 7 7 7 6 WD domain, G-beta repeat SDA1 PF05285.7 EGC37656.1 - 9.5e-59 199.2 76.1 6.2e-58 196.6 47.1 2.8 2 1 0 2 2 2 2 SDA1 NUC130_3NT PF08158.7 EGC37656.1 - 2e-21 75.9 0.6 5.2e-21 74.6 0.4 1.8 1 0 0 1 1 1 1 NUC130/3NT domain FNIP PF05725.7 EGC37657.1 - 2e-34 117.2 70.1 1.8e-07 30.9 0.0 13.9 7 3 3 10 10 10 7 FNIP Repeat LRR_4 PF12799.2 EGC37657.1 - 0.025 14.1 1.0 0.025 14.1 0.7 9.7 6 4 2 8 8 8 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC37657.1 - 2.3 8.0 35.8 2.5 7.9 3.3 8.1 5 3 3 9 9 9 0 Leucine rich repeat Toxin_64 PF15542.1 EGC37658.1 - 0.15 12.6 0.9 0.27 11.8 0.6 1.4 1 0 0 1 1 1 0 Putative toxin 64 IF4E PF01652.13 EGC37659.1 - 3e-27 95.1 4.1 1.2e-26 93.2 2.8 2.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E Cupin_8 PF13621.1 EGC37660.1 - 4.1e-45 154.2 1.7 4.6e-45 154.0 1.2 1.0 1 0 0 1 1 1 1 Cupin-like domain Cupin_4 PF08007.7 EGC37660.1 - 5.6e-09 35.6 0.0 1.3e-08 34.4 0.0 1.5 1 1 0 1 1 1 1 Cupin superfamily protein CotH PF08757.6 EGC37660.1 - 0.0046 16.2 0.1 0.0069 15.6 0.1 1.2 1 0 0 1 1 1 1 CotH protein JmjC PF02373.17 EGC37660.1 - 0.006 16.8 0.1 0.02 15.1 0.0 1.9 1 1 0 1 1 1 1 JmjC domain, hydroxylase WSC PF01822.14 EGC37662.1 - 3e-27 94.3 28.3 2.3e-17 62.6 6.8 4.0 5 0 0 5 5 5 2 WSC domain CAP PF00188.21 EGC37662.1 - 8.6e-16 58.5 0.9 8.6e-16 58.5 0.6 2.3 2 0 0 2 2 2 1 Cysteine-rich secretory protein family Macoilin PF09726.4 EGC37662.1 - 1.7 6.8 8.8 2 6.5 6.1 1.3 1 0 0 1 1 1 0 Transmembrane protein IBR PF01485.16 EGC37663.1 - 2.8e-07 30.2 45.4 5.8e-07 29.2 7.1 5.0 2 1 1 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGC37663.1 - 5e-07 29.4 7.6 5e-07 29.4 5.2 3.9 2 1 1 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC37663.1 - 0.00069 19.5 9.7 0.00069 19.5 6.8 4.4 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37663.1 - 0.001 18.7 8.5 0.001 18.7 5.9 4.8 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC37663.1 - 0.011 15.3 5.6 0.011 15.3 3.9 3.2 2 0 0 2 2 2 0 RING-type zinc-finger Saccharop_dh PF03435.13 EGC37664.1 - 3.1e-69 233.8 0.0 3.9e-69 233.4 0.0 1.1 1 0 0 1 1 1 1 Saccharopine dehydrogenase Shikimate_DH PF01488.15 EGC37664.1 - 0.018 15.1 0.0 0.04 14.0 0.0 1.6 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase DUF3980 PF13140.1 EGC37666.1 - 0.0062 16.7 0.2 0.0081 16.4 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3980) Pkinase PF00069.20 EGC37667.1 - 7.3e-12 44.9 0.5 1.3e-11 44.1 0.3 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37667.1 - 4.8e-07 29.1 0.1 8.8e-07 28.2 0.1 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase RIO1 PF01163.17 EGC37667.1 - 0.00017 20.9 0.3 0.00035 19.9 0.2 1.5 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC37667.1 - 0.00042 20.1 0.1 0.00091 19.0 0.1 1.5 1 1 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC37667.1 - 0.0071 15.2 0.2 0.011 14.5 0.2 1.2 1 0 0 1 1 1 1 Seadornavirus VP7 Choline_kinase PF01633.15 EGC37667.1 - 0.0084 15.7 0.7 0.019 14.5 0.5 1.5 1 0 0 1 1 1 1 Choline/ethanolamine kinase Kdo PF06293.9 EGC37667.1 - 0.013 14.5 0.1 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family Zip PF02535.17 EGC37667.1 - 0.021 13.8 0.4 0.021 13.8 0.3 1.4 2 0 0 2 2 2 0 ZIP Zinc transporter Pex14_N PF04695.8 EGC37667.1 - 0.025 14.6 1.9 0.039 14.0 1.3 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region FAM75 PF14650.1 EGC37667.1 - 0.029 13.7 13.8 0.043 13.2 9.6 1.1 1 0 0 1 1 1 0 FAM75 family Kinase-like PF14531.1 EGC37667.1 - 0.045 12.7 0.0 0.073 12.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like FNIP PF05725.7 EGC37668.1 - 7.1e-141 457.9 75.3 8.8e-16 57.5 0.8 12.8 12 1 1 13 13 13 12 FNIP Repeat Phage_min_tail PF05939.8 EGC37668.1 - 1.1e-05 25.3 0.1 7.6 6.5 0.0 6.5 5 4 3 8 8 8 2 Phage minor tail protein Peptidase_M22 PF00814.20 EGC37669.1 - 6.8e-83 278.2 0.0 7.9e-83 278.0 0.0 1.0 1 0 0 1 1 1 1 Glycoprotease family CTK3 PF12243.3 EGC37669.1 - 0.11 12.1 0.1 0.25 11.0 0.1 1.5 1 0 0 1 1 1 0 CTD kinase subunit gamma CTK3 CDC37_C PF08564.5 EGC37669.1 - 0.17 11.7 0.0 0.31 10.9 0.0 1.4 1 0 0 1 1 1 0 Cdc37 C terminal domain PWI PF01480.12 EGC37670.1 - 0.0012 18.9 2.2 0.0015 18.5 0.3 2.2 2 1 0 2 2 2 1 PWI domain EF-hand_7 PF13499.1 EGC37670.1 - 0.021 14.9 0.5 0.16 12.1 0.1 2.5 1 1 1 2 2 2 0 EF-hand domain pair MPC PF03650.8 EGC37671.1 - 2.3e-20 72.7 0.5 2.5e-20 72.5 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0041) ubiquitin PF00240.18 EGC37672.1 - 7e-23 79.8 0.3 3.8e-12 45.4 0.0 3.4 2 0 0 2 2 2 2 Ubiquitin family Rad60-SLD PF11976.3 EGC37672.1 - 1.3e-13 50.4 0.5 3e-06 26.8 0.1 3.5 2 0 0 2 2 2 2 Ubiquitin-2 like Rad60 SUMO-like A2M PF00207.17 EGC37672.1 - 4.4e-07 29.3 0.0 1.8e-06 27.4 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family A2M_N_2 PF07703.9 EGC37672.1 - 6.3e-05 22.7 0.0 0.00021 21.0 0.0 2.0 1 0 0 1 1 1 1 Alpha-2-macroglobulin family N-terminal region A2M_N PF01835.14 EGC37672.1 - 0.0017 18.6 0.0 0.009 16.2 0.0 2.3 1 0 0 1 1 1 1 MG2 domain RRN9 PF10680.4 EGC37672.1 - 0.2 11.3 0.0 0.5 10.1 0.0 1.6 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor TMEM154 PF15102.1 EGC37674.1 - 3.8e-05 23.4 1.0 8.5e-05 22.2 0.7 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF1191 PF06697.7 EGC37674.1 - 0.043 12.6 0.0 0.064 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1191) IncA PF04156.9 EGC37674.1 - 0.087 12.4 0.1 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 IncA protein EphA2_TM PF14575.1 EGC37674.1 - 0.11 12.8 2.2 3.2 8.2 0.3 2.8 2 1 1 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain DUF4014 PF13198.1 EGC37674.1 - 1.5 9.3 11.7 3.1 8.2 0.0 2.9 3 0 0 3 3 3 0 Protein of unknown function (DUF4014) YajC PF02699.10 EGC37674.1 - 8.9 6.0 7.2 0.37 10.4 0.1 2.1 2 0 0 2 2 2 0 Preprotein translocase subunit BSD PF03909.12 EGC37675.1 - 5.4e-13 48.4 0.1 1.5e-12 47.0 0.1 1.7 1 0 0 1 1 1 1 BSD domain Proteasome PF00227.21 EGC37676.1 - 6.1e-33 113.7 0.0 8e-33 113.3 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit AMP-binding PF00501.23 EGC37677.1 - 1.6e-92 310.1 0.0 1.9e-92 309.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC37677.1 - 0.0028 18.5 0.0 0.0093 16.8 0.0 1.9 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain SAM_2 PF07647.12 EGC37678.1 - 2.2e-07 30.6 0.2 0.00022 20.9 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC37678.1 - 5.7e-07 29.6 0.2 0.00034 20.7 0.0 2.4 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) SAM_PNT PF02198.11 EGC37678.1 - 0.011 15.4 0.0 0.14 11.9 0.0 2.3 2 0 0 2 2 2 0 Sterile alpha motif (SAM)/Pointed domain Ste50p-SAM PF09235.5 EGC37678.1 - 0.021 14.8 0.7 0.065 13.2 0.1 2.1 2 0 0 2 2 2 0 Ste50p, sterile alpha motif DUF3915 PF13054.1 EGC37678.1 - 0.15 11.9 0.7 0.54 10.2 0.0 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3915) PIG-L PF02585.12 EGC37679.1 - 1.3e-25 90.3 0.0 3.3e-25 89.0 0.0 1.7 1 0 0 1 1 1 1 GlcNAc-PI de-N-acetylase Glucosamine_iso PF01182.15 EGC37679.1 - 1.3e-14 54.3 0.0 3.8e-14 52.8 0.0 1.7 1 1 0 1 1 1 1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase Pox_polyA_pol_N PF12630.2 EGC37679.1 - 0.26 11.3 6.4 1.3 9.1 4.5 2.0 1 1 1 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Robl_LC7 PF03259.12 EGC37680.1 - 0.0014 18.1 0.0 0.0026 17.2 0.0 1.5 1 0 0 1 1 1 1 Roadblock/LC7 domain 4HBT PF03061.17 EGC37681.1 - 2.1e-11 43.7 0.0 2.9e-11 43.3 0.0 1.2 1 0 0 1 1 1 1 Thioesterase superfamily DUF4442 PF14539.1 EGC37681.1 - 0.017 15.0 0.0 0.022 14.7 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4442) DUF3672 PF12421.3 EGC37681.1 - 0.032 14.3 0.1 0.044 13.9 0.1 1.2 1 0 0 1 1 1 0 Fibronectin type III protein FlhC PF05280.6 EGC37681.1 - 0.097 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Flagellar transcriptional activator (FlhC) FNIP PF05725.7 EGC37682.1 - 2.5e-41 139.3 35.1 1.8e-08 34.2 2.3 9.8 2 2 6 10 10 10 10 FNIP Repeat zf-B_box PF00643.19 EGC37682.1 - 1.2e-05 25.0 6.4 2.5e-05 24.0 4.4 1.6 1 0 0 1 1 1 1 B-box zinc finger IBR PF01485.16 EGC37682.1 - 0.012 15.4 1.0 0.028 14.2 0.7 1.6 1 0 0 1 1 1 0 IBR domain Mucin PF01456.12 EGC37682.1 - 4.3 7.1 14.2 7.9 6.2 9.8 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein LisH PF08513.6 EGC37683.1 - 0.037 13.8 0.0 0.42 10.4 0.0 2.5 2 0 0 2 2 2 0 LisH VWC PF00093.13 EGC37684.1 - 0.36 10.9 4.3 0.47 10.6 3.0 1.2 1 0 0 1 1 1 0 von Willebrand factor type C domain CS PF04969.11 EGC37685.1 - 4.1e-16 59.2 6.1 4.1e-16 59.2 3.2 1.7 2 0 0 2 2 2 1 CS domain DUF4404 PF14357.1 EGC37685.1 - 0.068 13.5 0.3 0.13 12.6 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4404) SMC_N PF02463.14 EGC37686.1 - 1e-48 165.5 70.3 1.7e-46 158.2 48.7 4.5 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain SMC_hinge PF06470.8 EGC37686.1 - 1.2e-22 80.0 0.1 5e-22 78.1 0.1 2.2 1 0 0 1 1 1 1 SMC proteins Flexible Hinge Domain AAA_21 PF13304.1 EGC37686.1 - 1.4e-09 38.3 14.4 2.9e-06 27.4 5.5 4.6 3 2 1 4 4 4 2 AAA domain AAA_29 PF13555.1 EGC37686.1 - 0.00039 19.8 0.0 0.001 18.5 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain ATG16 PF08614.6 EGC37686.1 - 0.0031 17.3 15.3 0.0031 17.3 10.6 7.6 4 3 3 7 7 7 2 Autophagy protein 16 (ATG16) ABC_tran PF00005.22 EGC37686.1 - 0.013 15.8 0.0 0.013 15.8 0.0 7.4 4 3 1 5 5 5 0 ABC transporter AAA_23 PF13476.1 EGC37686.1 - 1.1 9.5 145.9 0.29 11.4 47.4 6.7 2 2 2 4 4 4 0 AAA domain Fcf2 PF08698.6 EGC37687.1 - 3.9e-14 52.4 0.4 3.9e-14 52.4 0.3 2.8 1 1 2 3 3 3 1 Fcf2 pre-rRNA processing UDPGP PF01704.13 EGC37687.1 - 0.01 14.4 5.8 0.0045 15.5 1.3 2.1 1 1 1 2 2 2 0 UTP--glucose-1-phosphate uridylyltransferase Nop25 PF09805.4 EGC37687.1 - 0.16 12.0 10.2 0.023 14.7 4.0 1.9 1 1 0 1 1 1 0 Nucleolar protein 12 (25kDa) MRP-S32 PF10210.4 EGC37687.1 - 0.48 10.7 3.3 0.5 10.7 1.0 1.9 1 1 1 2 2 2 0 Mitochondrial 28S ribosomal protein S32 SapB_1 PF05184.10 EGC37688.1 - 2.6e-14 52.5 12.7 8.6e-11 41.3 0.6 3.5 3 0 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC37688.1 - 4.9e-12 45.6 12.3 1.2e-10 41.1 0.5 3.1 4 0 0 4 4 4 2 Saposin-like type B, region 2 Thioredoxin PF00085.15 EGC37688.1 - 0.024 14.3 0.1 0.052 13.2 0.1 1.5 1 0 0 1 1 1 0 Thioredoxin DUF1251 PF06856.6 EGC37688.1 - 0.086 12.3 0.2 0.16 11.5 0.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1251) DUF3430 PF11912.3 EGC37689.1 - 3.4e-05 23.7 30.9 4.1e-05 23.5 21.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) ETRAMP PF09716.5 EGC37689.1 - 0.013 15.4 0.4 0.019 14.9 0.3 1.4 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) CHCH PF06747.8 EGC37689.1 - 0.25 11.3 1.5 0.6 10.1 0.1 2.5 2 0 0 2 2 2 0 CHCH domain DUF3586 PF12131.3 EGC37689.1 - 4.5 7.4 8.0 10 6.2 0.0 3.5 3 1 0 3 3 3 0 Protein of unknown function (DUF3586) PARG_cat PF05028.9 EGC37690.1 - 4.1e-130 433.9 0.0 7.5e-130 433.1 0.0 1.4 1 0 0 1 1 1 1 Poly (ADP-ribose) glycohydrolase (PARG) Myb_DNA-binding PF00249.26 EGC37691.1 - 7e-18 64.4 0.8 9.1e-09 35.2 0.0 2.8 2 0 0 2 2 2 2 Myb-like DNA-binding domain DnaJ PF00226.26 EGC37691.1 - 1.1e-17 63.4 0.2 1.1e-17 63.4 0.2 2.9 3 0 0 3 3 3 1 DnaJ domain Mucin PF01456.12 EGC37691.1 - 0.0047 16.6 12.4 0.0088 15.8 8.6 1.5 1 0 0 1 1 1 1 Mucin-like glycoprotein DUF3439 PF11921.3 EGC37691.1 - 0.18 11.5 8.6 0.43 10.3 6.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myotub-related PF06602.9 EGC37692.1 - 1.3e-123 412.3 2.1 1.3e-123 412.3 1.4 2.0 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Y_phosphatase3 PF13350.1 EGC37692.1 - 0.001 19.3 0.1 0.0049 17.1 0.0 2.2 2 0 0 2 2 2 1 Tyrosine phosphatase family AroM PF07302.6 EGC37692.1 - 0.006 15.9 0.3 0.012 14.9 0.2 1.4 1 0 0 1 1 1 1 AroM protein adh_short PF00106.20 EGC37693.1 - 5.4e-20 71.9 0.0 6.7e-20 71.6 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC37693.1 - 3.9e-16 59.5 0.0 4.9e-16 59.2 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC37693.1 - 2.6e-08 33.7 0.0 3.7e-08 33.2 0.0 1.2 1 0 0 1 1 1 1 KR domain Epimerase PF01370.16 EGC37693.1 - 0.00017 21.1 0.5 0.00036 20.0 0.4 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC37693.1 - 0.00086 19.3 0.0 0.0013 18.7 0.0 1.5 1 1 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC37693.1 - 0.0013 17.4 0.4 0.0021 16.7 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Polysacc_synt_2 PF02719.10 EGC37693.1 - 0.0064 15.4 0.1 0.008 15.1 0.1 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein NmrA PF05368.8 EGC37693.1 - 0.0083 15.3 0.1 0.023 13.9 0.0 1.7 2 0 0 2 2 2 1 NmrA-like family RmlD_sub_bind PF04321.12 EGC37693.1 - 0.015 14.2 0.0 0.022 13.6 0.0 1.2 1 0 0 1 1 1 0 RmlD substrate binding domain F-112 PF09645.5 EGC37693.1 - 0.095 12.5 0.1 0.3 10.9 0.0 1.9 2 0 0 2 2 2 0 F-112 protein CIAPIN1 PF05093.8 EGC37694.1 - 1e-24 86.4 17.8 1.3e-24 86.1 10.4 2.4 2 1 0 2 2 2 1 Cytokine-induced anti-apoptosis inhibitor 1, Fe-S biogenesis Pox_C4_C10 PF03336.8 EGC37694.1 - 0.0059 15.4 1.6 0.0071 15.1 1.1 1.3 1 0 0 1 1 1 1 Poxvirus C4/C10 protein YgbA_NO PF11756.3 EGC37694.1 - 0.41 10.6 3.1 0.28 11.1 0.9 1.7 2 0 0 2 2 2 0 Nitrous oxide-stimulated promoter MPC PF03650.8 EGC37696.1 - 2.4e-13 50.0 0.3 2.4e-13 50.0 0.2 1.4 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0041) CENP-Q PF13094.1 EGC37697.1 - 0.012 15.6 13.1 0.012 15.6 9.0 1.1 1 0 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit DUF1816 PF08846.5 EGC37697.1 - 1.8 8.3 6.8 0.82 9.4 1.9 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF1816) GIY-YIG PF01541.19 EGC37697.1 - 2.7 8.4 6.2 3.4 8.0 4.3 1.2 1 0 0 1 1 1 0 GIY-YIG catalytic domain TMEM51 PF15345.1 EGC37697.1 - 9.5 5.8 7.4 11 5.6 5.1 1.0 1 0 0 1 1 1 0 Transmembrane protein 51 Mito_carr PF00153.22 EGC37698.1 - 5.4e-73 240.7 5.9 1.4e-25 88.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RAP1 PF07218.6 EGC37698.1 - 0.06 11.4 0.1 0.078 11.0 0.0 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) RhoGAP PF00620.22 EGC37699.1 - 2.9e-35 121.1 0.1 4.4e-34 117.2 0.0 2.7 3 0 0 3 3 3 1 RhoGAP domain zf-MYND PF01753.13 EGC37699.1 - 7.4e-11 41.7 7.3 1.2e-10 41.0 5.1 1.3 1 0 0 1 1 1 1 MYND finger zf-Mss51 PF13824.1 EGC37699.1 - 0.0049 16.7 3.5 0.014 15.2 2.4 1.7 1 0 0 1 1 1 1 Zinc-finger of mitochondrial splicing suppressor 51 zf-RING_5 PF14634.1 EGC37700.1 - 2.1e-10 40.1 8.0 3.8e-10 39.3 5.5 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC37700.1 - 0.00011 21.7 5.4 0.0002 20.9 3.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC37700.1 - 0.00011 21.8 8.1 0.00018 21.2 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain DUF1272 PF06906.6 EGC37700.1 - 0.00024 20.8 3.6 0.00047 19.9 2.5 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_2 PF13923.1 EGC37700.1 - 0.0043 17.0 10.7 0.0093 15.9 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37700.1 - 0.0051 16.4 11.0 0.016 14.8 7.6 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGC37700.1 - 0.27 11.0 4.1 0.59 9.9 2.9 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein IncA PF04156.9 EGC37700.1 - 6 6.4 10.3 8.7 5.8 7.2 1.1 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 EGC37701.1 - 3.8e-88 286.5 15.0 1.2e-11 43.9 0.0 8.4 8 0 0 8 8 8 8 WD domain, G-beta repeat NLE PF08154.7 EGC37701.1 - 2.2e-16 59.6 3.3 4.3e-16 58.6 2.3 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain eIF2A PF08662.6 EGC37701.1 - 1.3e-12 47.8 0.4 0.0016 18.2 0.0 4.1 2 1 2 4 4 4 4 Eukaryotic translation initiation factor eIF2A Nup160 PF11715.3 EGC37701.1 - 8.5e-06 24.1 6.1 0.11 10.6 0.0 4.5 2 2 1 4 4 4 3 Nucleoporin Nup120/160 Nbas_N PF15492.1 EGC37701.1 - 1.8e-05 23.9 0.1 0.33 10.0 0.0 4.7 3 2 2 5 5 5 1 Neuroblastoma-amplified sequence, N terminal Nucleoporin_N PF08801.6 EGC37701.1 - 0.00021 20.1 3.4 0.38 9.4 0.1 3.4 2 1 0 2 2 2 2 Nup133 N terminal like PD40 PF07676.7 EGC37701.1 - 0.0033 17.0 5.3 13 5.5 0.0 4.7 5 0 0 5 5 5 0 WD40-like Beta Propeller Repeat BBS2_Mid PF14783.1 EGC37701.1 - 0.0044 16.7 0.1 5.2 6.8 0.0 3.6 2 2 1 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Cytochrom_D1 PF02239.11 EGC37701.1 - 0.011 14.0 0.0 0.8 7.9 0.0 3.1 2 1 1 3 3 3 0 Cytochrome D1 heme domain PQQ_2 PF13360.1 EGC37701.1 - 0.036 13.5 0.6 4.9 6.5 0.0 3.0 2 1 1 3 3 3 0 PQQ-like domain FCP1_C PF09309.5 EGC37701.1 - 0.087 12.1 0.0 7 5.8 0.0 3.0 3 0 0 3 3 3 0 FCP1, C-terminal Proteasome_A_N PF10584.4 EGC37701.1 - 0.17 11.2 0.4 2.9 7.3 0.0 2.8 2 0 0 2 2 2 0 Proteasome subunit A N-terminal signature dCMP_cyt_deam_1 PF00383.17 EGC37702.1 - 7.2e-05 22.3 0.0 0.0001 21.9 0.0 1.2 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region RasGEF PF00617.14 EGC37703.1 - 4.2e-63 212.4 1.1 4.2e-63 212.4 0.8 1.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC37703.1 - 1.6e-26 92.3 2.7 2.5e-26 91.7 0.3 2.5 2 0 0 2 2 2 1 RasGEF N-terminal motif zf-RING_2 PF13639.1 EGC37704.1 - 8.8e-11 41.4 7.0 1.5e-10 40.6 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC37704.1 - 6.1e-10 38.6 10.0 1.8e-09 37.1 7.0 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37704.1 - 1.1e-09 38.0 9.9 2.5e-09 36.9 6.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC37704.1 - 4.1e-09 35.9 6.3 7.5e-09 35.1 4.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37704.1 - 8.7e-09 34.9 7.6 1.7e-08 34.0 5.2 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC37704.1 - 8.4e-07 29.0 9.4 1.6e-06 28.1 6.1 1.8 1 1 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGC37704.1 - 3.7e-05 23.4 1.8 7.1e-05 22.5 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC37704.1 - 0.00019 20.9 8.6 0.00036 20.0 5.9 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC37704.1 - 0.0048 16.5 3.3 0.0048 16.5 2.3 3.2 2 1 1 3 3 3 1 RING-type zinc-finger zf-C3HC4_4 PF15227.1 EGC37704.1 - 0.0073 16.1 9.3 0.018 14.9 6.5 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING Prok-RING_4 PF14447.1 EGC37704.1 - 0.02 14.4 3.6 0.048 13.2 2.5 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_6 PF14835.1 EGC37704.1 - 0.034 13.9 1.8 0.071 12.9 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-UDP PF14569.1 EGC37704.1 - 0.12 12.1 1.9 0.26 11.0 1.3 1.5 1 0 0 1 1 1 0 Zinc-binding RING-finger DUF573 PF04504.9 EGC37704.1 - 9.4 6.5 9.3 8.1 6.8 0.8 3.3 3 0 0 3 3 3 0 Protein of unknown function, DUF573 Clathrin PF00637.15 EGC37705.1 - 9.4e-24 83.6 6.5 9.4e-24 83.6 4.5 2.9 3 1 0 3 3 3 1 Region in Clathrin and VPS Vps39_2 PF10367.4 EGC37705.1 - 3.6e-08 33.5 0.6 1.2e-07 31.8 0.4 1.9 1 0 0 1 1 1 1 Vacuolar sorting protein 39 domain 2 WD40 PF00400.27 EGC37705.1 - 6e-06 25.9 0.0 0.0053 16.5 0.0 4.0 4 0 0 4 4 4 1 WD domain, G-beta repeat zf-rbx1 PF12678.2 EGC37705.1 - 0.0058 16.7 0.4 0.037 14.1 0.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_2 PF13639.1 EGC37705.1 - 0.0086 15.8 6.6 0.0086 15.8 4.5 2.5 2 1 0 2 2 2 1 Ring finger domain zf-Apc11 PF12861.2 EGC37705.1 - 0.011 15.5 0.4 0.11 12.4 0.1 2.3 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGC37705.1 - 0.046 13.6 2.5 0.36 10.8 0.0 2.8 3 0 0 3 3 2 0 FANCL C-terminal domain zf-RING_5 PF14634.1 EGC37705.1 - 0.1 12.3 6.3 0.55 9.9 4.3 2.3 1 1 0 1 1 1 0 zinc-RING finger domain Vps39_1 PF10366.4 EGC37705.1 - 0.24 11.4 5.9 0.22 11.5 1.8 2.6 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 1 TFIIF_alpha PF05793.7 EGC37705.1 - 0.68 8.2 22.8 1.1 7.5 15.8 1.2 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pox_Ag35 PF03286.9 EGC37705.1 - 1.5 8.3 12.3 2.8 7.3 8.5 1.4 1 0 0 1 1 1 0 Pox virus Ag35 surface protein CDC45 PF02724.9 EGC37705.1 - 8.4 4.2 13.0 14 3.6 9.0 1.2 1 0 0 1 1 1 0 CDC45-like protein SapB_2 PF03489.12 EGC37706.1 - 1.3e-32 111.3 17.4 1.9e-11 43.7 1.5 3.9 3 0 0 3 3 3 3 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC37706.1 - 5.3e-28 96.2 16.5 3e-10 39.6 0.4 4.5 4 0 0 4 4 4 3 Saposin-like type B, region 1 Utp12 PF04003.7 EGC37706.1 - 0.011 15.5 0.1 9.8 6.1 0.0 3.0 3 0 0 3 3 3 0 Dip2/Utp12 Family E1-E2_ATPase PF00122.15 EGC37707.1 - 2.3e-59 200.2 3.5 2.3e-59 200.2 2.4 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Cation_ATPase_C PF00689.16 EGC37707.1 - 1.1e-42 145.6 4.7 1.1e-42 145.6 3.2 2.7 2 1 0 2 2 2 1 Cation transporting ATPase, C-terminus Hydrolase PF00702.21 EGC37707.1 - 1.7e-25 90.7 0.1 6.7e-25 88.7 0.1 2.0 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC37707.1 - 6.2e-17 61.3 0.0 1.3e-16 60.2 0.0 1.5 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit HAD PF12710.2 EGC37707.1 - 3.4e-15 56.6 0.0 6.6e-15 55.7 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC37707.1 - 2.3e-12 46.1 0.0 6.6e-12 44.7 0.0 1.8 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGC37707.1 - 0.00012 21.7 0.2 0.038 13.5 0.1 2.4 2 0 0 2 2 2 2 haloacid dehalogenase-like hydrolase NAD_synthase PF02540.12 EGC37707.1 - 0.07 12.0 0.0 0.13 11.1 0.0 1.3 1 0 0 1 1 1 0 NAD synthase Wzy_C PF04932.10 EGC37707.1 - 0.89 9.3 8.3 0.88 9.3 0.1 2.9 3 0 0 3 3 3 0 O-Antigen ligase Clp1 PF06807.9 EGC37708.1 - 9e-23 81.0 0.0 4.6e-22 78.7 0.0 2.1 1 1 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGC37708.1 - 5.5e-10 39.1 0.0 1.1e-09 38.1 0.0 1.5 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_14 PF13173.1 EGC37708.1 - 0.0079 16.0 0.0 0.03 14.2 0.0 2.0 1 0 0 1 1 1 1 AAA domain DUF2737 PF10930.3 EGC37709.1 - 0.05 13.2 0.6 0.12 11.9 0.4 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2737) Tim54 PF11711.3 EGC37709.1 - 0.1 11.1 0.0 0.11 11.0 0.0 1.0 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 Pol_alpha_B_N PF08418.5 EGC37709.1 - 0.42 10.1 14.3 0.43 10.0 9.9 1.0 1 0 0 1 1 1 0 DNA polymerase alpha subunit B N-terminal SSP160 PF06933.6 EGC37709.1 - 0.48 8.3 14.8 0.49 8.2 10.3 1.0 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF605 PF04652.11 EGC37709.1 - 2.3 7.5 14.7 2.5 7.4 10.2 1.0 1 0 0 1 1 1 0 Vta1 like Herpes_capsid PF06112.6 EGC37709.1 - 2.5 8.1 14.2 2.9 7.9 9.9 1.2 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Macoilin PF09726.4 EGC37709.1 - 9.4 4.3 14.6 11 4.1 10.1 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1712 PF08217.6 EGC37710.1 - 8e-77 258.8 19.3 1.1e-70 238.5 13.3 2.6 1 1 0 1 1 1 1 Fungal domain of unknown function (DUF1712) Gelsolin PF00626.17 EGC37711.1 - 1.5e-50 168.8 1.2 4.2e-12 45.5 0.0 5.5 5 0 0 5 5 5 5 Gelsolin repeat DUF1900 PF08954.6 EGC37711.1 - 5.3e-38 129.6 0.1 4.5e-36 123.3 0.0 3.0 3 0 0 3 3 3 1 Domain of unknown function (DUF1900) WD40 PF00400.27 EGC37711.1 - 4.2e-20 70.7 3.7 3.1e-09 36.3 0.4 4.0 3 0 0 3 3 3 3 WD domain, G-beta repeat VHP PF02209.14 EGC37711.1 - 3.1e-14 52.3 2.3 7.2e-14 51.1 1.6 1.7 1 0 0 1 1 1 1 Villin headpiece domain PH PF00169.24 EGC37711.1 - 4.8e-13 49.2 7.4 3.8e-05 23.8 0.2 4.8 5 0 0 5 5 5 3 PH domain DUF1899 PF08953.6 EGC37711.1 - 1.9e-07 30.5 0.0 5e-07 29.2 0.0 1.8 1 0 0 1 1 1 1 Domain of unknown function (DUF1899) PH_6 PF15406.1 EGC37711.1 - 0.0078 16.2 0.1 14 5.8 0.0 3.9 3 0 0 3 3 3 1 Pleckstrin homology domain Mcp5_PH PF12814.2 EGC37711.1 - 0.11 12.4 6.6 3.7 7.4 0.1 3.7 4 0 0 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology SapB_1 PF05184.10 EGC37713.1 - 0.011 15.5 1.6 0.21 11.4 0.1 2.8 2 0 0 2 2 2 0 Saposin-like type B, region 1 CNH PF00780.17 EGC37713.1 - 0.012 15.0 0.1 0.016 14.6 0.1 1.4 1 0 0 1 1 1 0 CNH domain DUF912 PF06024.7 EGC37714.1 - 0.0021 18.0 0.4 0.0021 18.0 0.3 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) RRM_1 PF00076.17 EGC37715.1 - 5.7e-16 57.9 0.1 9.3e-16 57.2 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37715.1 - 1.2e-10 41.2 0.0 1.9e-10 40.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37715.1 - 2.2e-07 30.5 0.0 3.8e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC37715.1 - 8.6e-05 22.3 0.2 0.00019 21.2 0.1 1.5 1 0 0 1 1 1 1 RNA binding motif zf-CCHC PF00098.18 EGC37715.1 - 9.1e-05 22.2 2.7 0.00017 21.3 1.9 1.5 1 0 0 1 1 1 1 Zinc knuckle Limkain-b1 PF11608.3 EGC37715.1 - 0.0008 19.1 0.1 0.0019 17.9 0.0 1.6 1 0 0 1 1 1 1 Limkain b1 DbpA PF03880.10 EGC37715.1 - 0.11 12.1 0.0 0.19 11.3 0.0 1.4 1 0 0 1 1 1 0 DbpA RNA binding domain CDC45 PF02724.9 EGC37715.1 - 0.88 7.5 16.4 0.92 7.4 11.4 1.2 1 0 0 1 1 1 0 CDC45-like protein MIP-T3 PF10243.4 EGC37715.1 - 1.2 7.5 22.3 1.5 7.2 15.5 1.1 1 0 0 1 1 1 0 Microtubule-binding protein MIP-T3 DUF1777 PF08648.7 EGC37715.1 - 5.9 6.5 61.2 3.3 7.4 36.8 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF1777) zf-CCHC PF00098.18 EGC37716.1 - 1.1e-08 34.5 1.6 2e-08 33.7 1.1 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_4 PF14392.1 EGC37716.1 - 0.002 17.7 1.7 0.0035 16.9 1.2 1.4 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC_2 PF13696.1 EGC37716.1 - 0.0062 16.0 0.8 0.011 15.2 0.6 1.3 1 0 0 1 1 1 1 Zinc knuckle DBR1 PF05011.8 EGC37717.1 - 7.4e-15 55.0 3.4 7.4e-15 55.0 2.4 2.2 2 1 0 2 2 2 1 Lariat debranching enzyme, C-terminal domain Metallophos PF00149.23 EGC37717.1 - 3.4e-10 39.6 0.4 7.2e-10 38.5 0.3 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC37717.1 - 0.00013 21.7 0.0 0.00029 20.6 0.0 1.6 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Methyltransf_2 PF00891.13 EGC37718.1 - 3.4e-54 183.5 0.0 4.4e-54 183.2 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Ubie_methyltran PF01209.13 EGC37718.1 - 0.0011 18.1 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_18 PF12847.2 EGC37718.1 - 0.0015 19.0 0.0 0.0032 18.0 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC37718.1 - 0.0021 18.3 0.0 0.057 13.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain HTH_28 PF13518.1 EGC37718.1 - 0.07 13.1 0.0 1.8 8.6 0.0 2.3 2 0 0 2 2 2 0 Helix-turn-helix domain Pox_polyA_pol_N PF12630.2 EGC37718.1 - 0.27 11.3 2.4 3.8 7.6 0.2 3.4 3 1 0 4 4 4 0 Poxvirus poly(A) polymerase N-terminal domain Ldh_1_C PF02866.13 EGC37719.1 - 4.6e-40 137.1 0.0 1.4e-39 135.5 0.0 1.7 2 0 0 2 2 2 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGC37719.1 - 6.9e-34 116.6 0.8 1.1e-33 116.0 0.6 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain RNase_PH PF01138.16 EGC37720.1 - 1.9e-23 83.2 0.0 5.5e-23 81.7 0.0 1.8 2 1 0 2 2 2 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGC37720.1 - 8.1e-12 44.9 0.1 1.5e-11 44.0 0.1 1.5 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 DUF2372 PF10178.4 EGC37720.1 - 0.037 14.1 0.1 4.5 7.4 0.0 2.5 2 0 0 2 2 2 0 Uncharacterised conserved protein (DUF2372) Actin PF00022.14 EGC37721.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC37721.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CBS PF00571.23 EGC37722.1 - 3.1e-23 81.3 0.1 6.2e-08 32.3 0.0 4.4 5 0 0 5 5 5 3 CBS domain VKOR PF07884.9 EGC37723.1 - 1.1e-16 60.9 14.9 1.9e-16 60.1 10.3 1.3 1 0 0 1 1 1 1 Vitamin K epoxide reductase family COPI_assoc PF08507.5 EGC37723.1 - 2.6 7.7 10.7 0.32 10.6 3.2 2.2 1 1 1 2 2 2 0 COPI associated protein Mito_carr PF00153.22 EGC37724.1 - 8.3e-67 220.9 1.2 1.4e-24 85.5 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein DUF605 PF04652.11 EGC37725.1 - 0.023 14.1 20.6 0.03 13.7 14.3 1.2 1 0 0 1 1 1 0 Vta1 like Pox_A9 PF04835.7 EGC37726.1 - 0.22 11.4 1.9 0.33 10.8 1.3 1.3 1 0 0 1 1 1 0 A9 protein conserved region Folate_carrier PF01770.13 EGC37726.1 - 1.9 6.9 3.6 0.4 9.1 0.0 1.6 2 0 0 2 2 2 0 Reduced folate carrier Pox_RNA_Pol_19 PF05320.7 EGC37727.1 - 0.018 14.8 1.7 0.023 14.4 1.2 1.1 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit PTS_2-RNA PF01885.11 EGC37728.1 - 7.7e-63 211.1 0.2 9.5e-63 210.8 0.2 1.0 1 0 0 1 1 1 1 RNA 2'-phosphotransferase, Tpt1 / KptA family HECT PF00632.20 EGC37729.1 - 9.1e-61 205.7 0.2 9.1e-61 205.7 0.1 4.9 5 0 0 5 5 5 1 HECT-domain (ubiquitin-transferase) SPRY PF00622.23 EGC37729.1 - 4.1e-19 68.8 0.4 1.6e-18 66.9 0.3 2.1 1 0 0 1 1 1 1 SPRY domain PH PF00169.24 EGC37729.1 - 5.5e-17 61.8 0.3 5.5e-17 61.8 0.2 4.8 4 0 0 4 4 4 1 PH domain PH_9 PF15410.1 EGC37729.1 - 1.3e-07 31.8 3.4 1.6e-07 31.4 0.2 2.7 2 0 0 2 2 2 1 Pleckstrin homology domain SNF2_N PF00176.18 EGC37730.1 - 2.8e-67 226.6 0.4 8.2e-67 225.1 0.3 1.8 1 0 0 1 1 1 1 SNF2 family N-terminal domain zf-RING_2 PF13639.1 EGC37730.1 - 5.9e-08 32.4 10.7 5.9e-08 32.4 7.4 3.3 3 1 1 4 4 4 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC37730.1 - 3.2e-06 27.0 12.7 3.2e-06 27.0 8.8 3.0 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) Helicase_C PF00271.26 EGC37730.1 - 4.7e-05 23.1 0.2 0.00015 21.5 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain zf-C3HC4 PF00097.20 EGC37730.1 - 9.3e-05 22.0 10.9 9.3e-05 22.0 7.6 3.4 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37730.1 - 0.00092 18.8 9.5 0.00092 18.8 6.6 2.9 2 1 1 3 3 3 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC37730.1 - 0.0071 16.0 4.2 0.0071 16.0 2.9 3.5 2 1 0 2 2 2 1 RING-type zinc-finger AIG2_2 PF13772.1 EGC37731.1 - 0.025 14.6 4.8 2.4 8.3 0.1 2.5 2 0 0 2 2 2 0 AIG2-like family Wbp11 PF09429.5 EGC37731.1 - 0.28 11.1 8.6 0.59 10.1 0.3 2.4 2 0 0 2 2 2 0 WW domain binding protein 11 FlxA PF14282.1 EGC37731.1 - 2.7 7.9 10.1 1.5 8.7 1.8 2.5 1 1 1 2 2 2 0 FlxA-like protein Sof1 PF04158.9 EGC37731.1 - 3 7.9 8.2 1.3 9.0 0.7 2.9 3 0 0 3 3 3 0 Sof1-like domain SPX PF03105.14 EGC37731.1 - 6.4 6.4 24.5 6.9 6.3 15.5 1.9 1 1 1 2 2 2 0 SPX domain ACCA PF03255.9 EGC37731.1 - 6.5 6.2 7.1 1.9 8.0 1.0 2.2 1 1 0 2 2 2 0 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit YgaB PF14182.1 EGC37731.1 - 7.8 6.8 13.1 7.6 6.8 0.2 3.2 2 1 1 3 3 3 0 YgaB-like protein Abhydrolase_6 PF12697.2 EGC37732.1 - 2e-09 37.6 0.0 2.6e-09 37.2 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC37732.1 - 1e-07 31.7 0.0 1.6e-07 31.1 0.0 1.2 1 0 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC37732.1 - 0.0057 16.4 0.0 0.0073 16.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S28 PF05577.7 EGC37732.1 - 0.014 13.9 0.0 0.024 13.2 0.0 1.3 1 0 0 1 1 1 0 Serine carboxypeptidase S28 Peptidase_S9 PF00326.16 EGC37732.1 - 0.13 11.4 0.0 0.22 10.7 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DJ-1_PfpI PF01965.19 EGC37733.1 - 1.6e-29 102.2 0.1 1.9e-29 101.9 0.1 1.1 1 0 0 1 1 1 1 DJ-1/PfpI family DUF4066 PF13278.1 EGC37733.1 - 6e-10 38.6 0.0 8.3e-10 38.1 0.0 1.3 1 1 0 1 1 1 1 Putative amidotransferase GATase PF00117.23 EGC37733.1 - 0.0031 16.9 0.0 0.0044 16.5 0.0 1.4 1 1 0 1 1 1 1 Glutamine amidotransferase class-I GATase_3 PF07685.9 EGC37733.1 - 0.022 14.3 0.0 0.038 13.5 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain Peptidase_C26 PF07722.8 EGC37733.1 - 0.028 13.8 0.0 0.12 11.8 0.0 1.9 1 1 0 1 1 1 0 Peptidase C26 GATase_5 PF13507.1 EGC37733.1 - 0.12 11.2 0.0 0.19 10.5 0.0 1.4 1 1 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain ELFV_dehydrog PF00208.16 EGC37734.1 - 4.6e-50 170.4 0.0 7.4e-50 169.7 0.0 1.3 1 0 0 1 1 1 1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase Bac_GDH PF05088.7 EGC37734.1 - 1.9e-25 88.6 0.0 8.4e-16 56.6 0.0 2.1 2 0 0 2 2 2 2 Bacterial NAD-glutamate dehydrogenase ELFV_dehydrog_N PF02812.13 EGC37734.1 - 0.0057 16.2 0.0 0.014 15.0 0.0 1.6 1 0 0 1 1 1 1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain Thy1 PF02511.10 EGC37735.1 - 3.4e-53 179.8 0.1 4.3e-53 179.5 0.1 1.1 1 0 0 1 1 1 1 Thymidylate synthase complementing protein CMS1 PF14617.1 EGC37736.1 - 6.5e-11 41.7 21.6 2.8e-09 36.4 15.0 2.8 1 1 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit RabGAP-TBC PF00566.13 EGC37738.1 - 1.3e-23 83.6 14.0 7e-15 55.0 2.2 9.2 5 3 1 6 6 6 2 Rab-GTPase-TBC domain UME PF08064.8 EGC37738.1 - 7.5 6.5 7.3 9.3 6.2 0.1 3.7 3 1 1 4 4 4 0 UME (NUC010) domain PGM_PMM_IV PF00408.15 EGC37739.1 - 0.11 12.5 0.0 0.15 12.0 0.0 1.2 1 0 0 1 1 1 0 Phosphoglucomutase/phosphomannomutase, C-terminal domain DUF3908 PF13048.1 EGC37740.1 - 0.018 15.0 0.3 0.052 13.5 0.2 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3908) Asp-B-Hydro_N PF05279.6 EGC37740.1 - 0.93 9.2 20.7 1.2 8.9 14.3 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region Ank_2 PF12796.2 EGC37741.1 - 4.4e-07 30.1 1.5 9.3e-05 22.7 0.1 3.9 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC37741.1 - 7.4e-06 25.7 3.6 1.1 9.7 0.0 5.2 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGC37741.1 - 0.0068 16.6 5.3 12 6.3 0.0 4.7 4 0 0 4 4 4 2 Ankyrin repeats (many copies) AAA PF00004.24 EGC37742.1 - 4.3e-37 127.2 0.0 4.3e-37 127.2 0.0 2.1 3 1 1 4 4 2 1 ATPase family associated with various cellular activities (AAA) MIT PF04212.13 EGC37742.1 - 2.8e-09 36.7 3.6 7.5e-09 35.3 2.5 1.8 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EGC37742.1 - 2.2e-05 24.5 1.6 0.0015 18.6 1.1 3.3 1 1 0 1 1 1 1 AAA domain Vps4_C PF09336.5 EGC37742.1 - 2.5e-05 24.0 0.0 8.5e-05 22.3 0.0 1.9 2 0 0 2 2 1 1 Vps4 C terminal oligomerisation domain RuvB_N PF05496.7 EGC37742.1 - 5.1e-05 22.4 0.0 0.00015 20.9 0.0 1.7 1 1 1 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_2 PF07724.9 EGC37742.1 - 5.3e-05 23.2 0.1 0.00026 20.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_5 PF07728.9 EGC37742.1 - 0.00043 20.0 0.1 0.0039 16.9 0.1 2.7 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) TIP49 PF06068.8 EGC37742.1 - 0.0005 18.9 0.0 0.0011 17.7 0.0 1.5 1 0 0 1 1 1 1 TIP49 C-terminus AAA_14 PF13173.1 EGC37742.1 - 0.00058 19.7 1.2 0.012 15.5 0.0 3.0 2 1 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC37742.1 - 0.0034 18.1 0.1 0.024 15.4 0.0 2.4 2 0 0 2 2 2 1 AAA domain Mg_chelatase PF01078.16 EGC37742.1 - 0.0036 16.5 0.1 0.009 15.1 0.0 1.6 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI IstB_IS21 PF01695.12 EGC37742.1 - 0.0037 16.7 0.0 0.0076 15.6 0.0 1.5 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGC37742.1 - 0.007 16.0 0.2 0.038 13.7 0.0 2.2 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EGC37742.1 - 0.008 15.6 0.2 0.25 10.7 0.1 2.3 1 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC37742.1 - 0.0085 16.0 1.0 0.061 13.2 0.2 2.6 2 1 0 2 2 2 1 AAA ATPase domain AAA_33 PF13671.1 EGC37742.1 - 0.014 15.2 0.2 0.1 12.4 0.0 2.4 3 0 0 3 3 2 0 AAA domain KaiC PF06745.8 EGC37742.1 - 0.046 12.8 0.2 6.8 5.7 0.0 2.8 1 1 1 2 2 2 0 KaiC Shisa PF13908.1 EGC37742.1 - 0.11 12.7 0.1 0.11 12.7 0.1 2.6 2 1 0 2 2 1 0 Wnt and FGF inhibitory regulator DUF2894 PF11445.3 EGC37742.1 - 0.15 12.3 4.8 0.33 11.1 0.3 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF2894) AAA_18 PF13238.1 EGC37742.1 - 0.61 10.3 0.0 0.61 10.3 0.0 3.5 4 2 0 4 4 4 0 AAA domain AAA_28 PF13521.1 EGC37742.1 - 1.6 8.6 0.0 1.6 8.6 0.0 2.6 3 0 0 3 3 2 0 AAA domain HAD_2 PF13419.1 EGC37743.1 - 1.2e-06 28.8 0.0 6.9e-05 23.1 0.0 2.2 2 0 0 2 2 2 2 Haloacid dehalogenase-like hydrolase BSD PF03909.12 EGC37743.1 - 0.13 11.9 0.9 0.65 9.7 0.7 2.2 2 1 0 2 2 2 0 BSD domain GcrA PF07750.6 EGC37744.1 - 0.011 15.9 2.9 0.014 15.5 2.0 1.1 1 0 0 1 1 1 0 GcrA cell cycle regulator Rho_N PF07498.7 EGC37744.1 - 0.026 14.2 0.0 0.052 13.3 0.0 1.7 1 1 0 1 1 1 0 Rho termination factor, N-terminal domain DUF2161 PF09929.4 EGC37744.1 - 0.12 12.2 1.6 0.15 11.9 1.1 1.1 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2161) Senescence_reg PF04520.8 EGC37744.1 - 0.22 12.0 3.3 0.24 11.9 2.3 1.1 1 0 0 1 1 1 0 Senescence regulator SAPS PF04499.10 EGC37744.1 - 0.86 8.1 3.5 0.99 7.9 2.4 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein MRP-S31 PF15433.1 EGC37744.1 - 0.94 8.8 7.0 1.1 8.6 4.9 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 adh_short PF00106.20 EGC37745.1 - 7.3e-07 29.2 0.0 3.9e-06 26.8 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase KR PF08659.5 EGC37745.1 - 0.0012 18.4 0.0 0.0023 17.6 0.0 1.3 1 0 0 1 1 1 1 KR domain adh_short_C2 PF13561.1 EGC37745.1 - 0.0019 17.9 0.0 0.036 13.8 0.0 2.3 2 0 0 2 2 2 1 Enoyl-(Acyl carrier protein) reductase NAD_binding_10 PF13460.1 EGC37745.1 - 0.14 12.1 0.0 0.89 9.5 0.0 2.0 2 0 0 2 2 2 0 NADH(P)-binding FAE1_CUT1_RppA PF08392.7 EGC37746.1 - 9.6e-125 415.4 0.0 1.3e-124 415.0 0.0 1.1 1 0 0 1 1 1 1 FAE1/Type III polyketide synthase-like protein ACP_syn_III_C PF08541.5 EGC37746.1 - 8.4e-11 41.7 0.0 1.5e-09 37.7 0.0 2.3 2 0 0 2 2 2 1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal Chal_sti_synt_C PF02797.10 EGC37746.1 - 9.1e-10 38.6 0.0 1.7e-09 37.7 0.0 1.4 1 0 0 1 1 1 1 Chalcone and stilbene synthases, C-terminal domain Chal_sti_synt_N PF00195.14 EGC37746.1 - 5.9e-06 25.6 0.0 1.5e-05 24.3 0.0 1.6 1 0 0 1 1 1 1 Chalcone and stilbene synthases, N-terminal domain BPD_transp_1 PF00528.17 EGC37746.1 - 0.0069 15.9 0.8 0.011 15.2 0.5 1.3 1 0 0 1 1 1 1 Binding-protein-dependent transport system inner membrane component ACP_syn_III PF08545.5 EGC37746.1 - 0.012 15.2 0.0 0.025 14.2 0.0 1.4 1 0 0 1 1 1 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III adh_short PF00106.20 EGC37748.1 - 4.9e-24 85.1 0.0 5.9e-24 84.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC37748.1 - 1.9e-17 63.8 0.0 2.7e-17 63.3 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase DUF1776 PF08643.5 EGC37748.1 - 1.1e-08 34.5 0.0 2.3e-08 33.5 0.0 1.4 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EGC37748.1 - 1.2e-07 31.5 0.0 1.6e-07 31.1 0.0 1.1 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC37748.1 - 0.00062 19.8 0.0 0.0018 18.3 0.0 1.8 1 1 0 1 1 1 1 NADH(P)-binding 3HCDH_N PF02737.13 EGC37748.1 - 0.0021 17.7 0.0 0.0034 17.0 0.0 1.3 1 0 0 1 1 1 1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain NAD_binding_2 PF03446.10 EGC37748.1 - 0.007 16.2 0.0 0.018 14.8 0.0 1.8 1 1 1 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase F420_oxidored PF03807.12 EGC37748.1 - 0.0074 16.6 0.1 0.019 15.3 0.0 1.7 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent Adenylsucc_synt PF00709.16 EGC37748.1 - 0.0088 14.7 0.0 0.011 14.4 0.0 1.1 1 0 0 1 1 1 1 Adenylosuccinate synthetase Shikimate_DH PF01488.15 EGC37748.1 - 0.013 15.5 0.0 0.027 14.5 0.0 1.5 1 0 0 1 1 1 0 Shikimate / quinate 5-dehydrogenase Pkinase PF00069.20 EGC37749.1 - 2.4e-52 177.6 0.1 2.4e-52 177.6 0.1 3.0 2 1 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37749.1 - 5.6e-21 74.7 0.0 5.6e-21 74.7 0.0 1.7 2 0 0 2 2 2 1 Protein tyrosine kinase APH PF01636.18 EGC37749.1 - 0.019 14.7 0.0 0.019 14.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF791 PF05631.9 EGC37751.1 - 2e-102 342.5 17.9 2.5e-102 342.1 12.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF791) MFS_1 PF07690.11 EGC37751.1 - 7.2e-20 70.9 32.3 1.4e-19 70.0 22.4 1.5 1 1 0 1 1 1 1 Major Facilitator Superfamily Cation_efflux PF01545.16 EGC37752.1 - 7e-68 228.7 9.0 8.6e-68 228.4 6.2 1.1 1 0 0 1 1 1 1 Cation efflux family PBP1_TM PF14812.1 EGC37752.1 - 0.026 14.7 0.7 0.026 14.7 0.5 3.5 2 1 1 3 3 3 0 Transmembrane domain of transglycosylase PBP1 at N-terminal ATP-synt_G PF04718.10 EGC37752.1 - 0.043 14.4 0.0 0.091 13.4 0.0 1.5 1 0 0 1 1 1 0 Mitochondrial ATP synthase g subunit Neur_chan_memb PF02932.11 EGC37752.1 - 1.2 9.0 13.9 7.2 6.4 0.1 2.4 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pribosyltran_N PF13793.1 EGC37753.1 - 3.6e-42 142.7 0.2 5.1e-41 139.0 0.0 2.4 2 1 0 2 2 2 1 N-terminal domain of ribose phosphate pyrophosphokinase Pribosyl_synth PF14572.1 EGC37753.1 - 3.2e-30 105.2 1.3 2.5e-29 102.3 0.2 2.4 2 1 1 3 3 3 1 Phosphoribosyl synthetase-associated domain Pribosyltran PF00156.22 EGC37753.1 - 0.00031 20.4 1.0 0.0018 17.9 0.7 2.2 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Mob1_phocein PF03637.12 EGC37754.1 - 1.2e-52 178.1 0.1 1.4e-52 177.9 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family VPR PF00522.13 EGC37755.1 - 0.12 12.1 0.0 0.48 10.2 0.0 2.0 1 0 0 1 1 1 0 VPR/VPX protein BAR PF03114.13 EGC37758.1 - 0.098 12.1 2.6 0.13 11.7 1.8 1.1 1 0 0 1 1 1 0 BAR domain Peptidase_M1 PF01433.15 EGC37760.1 - 2e-140 468.3 0.3 2.9e-140 467.8 0.2 1.2 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGC37760.1 - 4.7e-54 183.8 0.0 7.2e-54 183.2 0.0 1.3 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGC37760.1 - 1.1e-19 70.6 0.3 1.9e-19 69.9 0.2 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily Peptidase_M48 PF01435.13 EGC37760.1 - 0.027 14.0 0.0 0.19 11.2 0.0 2.1 2 0 0 2 2 2 0 Peptidase family M48 tRNA_anti-codon PF01336.20 EGC37761.1 - 0.012 15.4 0.0 0.018 14.8 0.0 1.4 1 0 0 1 1 1 0 OB-fold nucleic acid binding domain CTDII PF01556.13 EGC37761.1 - 0.097 12.5 0.2 11 5.9 0.0 2.4 1 1 1 2 2 2 0 DnaJ C terminal domain RelA_SpoT PF04607.12 EGC37762.1 - 4.2e-06 26.7 0.3 1.1e-05 25.4 0.2 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins DASH_Dad1 PF08649.5 EGC37762.1 - 0.76 9.5 0.1 0.76 9.5 0.0 3.3 5 0 0 5 5 5 0 DASH complex subunit Dad1 WD40 PF00400.27 EGC37763.1 - 2.5e-19 68.3 28.7 1.7e-07 30.8 0.2 8.8 10 0 0 10 10 10 5 WD domain, G-beta repeat adh_short PF00106.20 EGC37765.1 - 0.0011 18.8 0.0 0.0017 18.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase NAD_binding_10 PF13460.1 EGC37765.1 - 0.24 11.3 0.0 0.45 10.5 0.0 1.4 1 0 0 1 1 1 0 NADH(P)-binding KR PF08659.5 EGC37765.1 - 0.42 10.2 0.0 0.65 9.6 0.0 1.2 1 0 0 1 1 1 0 KR domain Aldedh PF00171.17 EGC37766.1 - 4.6e-167 556.0 0.0 5.1e-167 555.8 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family DUF1487 PF07368.6 EGC37766.1 - 0.082 12.1 0.1 0.44 9.7 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1487) TPR_11 PF13414.1 EGC37767.1 - 3.6e-09 36.1 14.1 0.00043 19.8 0.4 4.6 4 0 0 4 4 4 2 TPR repeat TPR_1 PF00515.23 EGC37767.1 - 7.9e-09 34.7 14.3 1.3e-05 24.5 0.2 5.2 4 0 0 4 4 4 2 Tetratricopeptide repeat Sel1 PF08238.7 EGC37767.1 - 1.9e-08 34.6 12.1 0.047 14.3 0.1 5.4 5 0 0 5 5 5 3 Sel1 repeat TPR_16 PF13432.1 EGC37767.1 - 1.5e-06 28.6 7.4 0.98 10.1 0.0 4.4 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC37767.1 - 1.5e-06 27.6 15.1 0.00026 20.6 0.1 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC37767.1 - 3.9e-06 27.0 1.7 0.00031 21.1 0.0 3.6 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37767.1 - 1.5e-05 24.8 10.7 0.1 12.5 0.0 4.8 4 1 0 4 4 4 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC37767.1 - 0.00095 19.1 2.8 1.9 8.9 0.0 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC37767.1 - 0.011 15.5 10.9 0.9 9.4 0.1 5.4 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37767.1 - 0.011 15.4 0.1 0.011 15.4 0.1 5.0 6 0 0 6 6 6 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC37767.1 - 0.03 14.1 0.7 0.19 11.6 0.0 2.7 2 0 0 2 2 2 0 Fis1 C-terminal tetratricopeptide repeat TPR_6 PF13174.1 EGC37767.1 - 7.5 7.2 8.9 7.4 7.2 0.1 4.4 5 0 0 5 5 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37767.1 - 9.8 6.6 7.3 13 6.1 0.0 4.2 5 1 0 5 5 4 0 Tetratricopeptide repeat Toxin_17 PF08086.6 EGC37769.1 - 2.7 8.1 6.8 3.8 7.6 1.8 2.3 2 0 0 2 2 2 0 Ergtoxin family CH PF00307.26 EGC37770.1 - 1.5e-32 111.8 12.2 1.2e-12 47.7 0.1 4.2 4 0 0 4 4 4 4 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC37770.1 - 0.043 13.4 0.4 2 8.0 0.1 3.0 3 0 0 3 3 3 0 CAMSAP CH domain WD40 PF00400.27 EGC37771.1 - 5.2e-22 76.8 1.7 1.7e-06 27.6 0.1 6.0 6 0 0 6 6 6 3 WD domain, G-beta repeat UTP15_C PF09384.5 EGC37771.1 - 1e-18 67.4 1.8 1.5e-18 66.8 1.3 1.3 1 0 0 1 1 1 1 UTP15 C terminal PQQ_2 PF13360.1 EGC37771.1 - 0.0033 16.9 0.1 5.8 6.3 0.1 3.5 1 1 3 4 4 4 2 PQQ-like domain p450 PF00067.17 EGC37771.1 - 0.011 14.2 1.3 0.017 13.6 0.9 1.3 1 0 0 1 1 1 0 Cytochrome P450 PQQ_3 PF13570.1 EGC37771.1 - 0.024 14.9 0.2 4.2 7.7 0.0 3.4 3 0 0 3 3 3 0 PQQ-like domain Utp13 PF08625.6 EGC37771.1 - 0.15 11.6 2.0 0.27 10.8 1.4 1.4 1 0 0 1 1 1 0 Utp13 specific WD40 associated domain ABC_tran PF00005.22 EGC37772.1 - 0.00015 22.1 2.1 0.00015 22.1 1.5 3.0 4 0 0 4 4 4 1 ABC transporter Miro PF08477.8 EGC37772.1 - 0.0029 18.1 0.1 0.014 15.8 0.0 2.3 2 0 0 2 2 2 1 Miro-like protein NB-ARC PF00931.17 EGC37772.1 - 0.0031 16.4 0.1 0.0063 15.4 0.0 1.5 1 0 0 1 1 1 1 NB-ARC domain MMR_HSR1 PF01926.18 EGC37772.1 - 0.0069 16.3 0.1 0.034 14.0 0.0 2.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase AAA_14 PF13173.1 EGC37772.1 - 0.009 15.9 0.1 0.029 14.2 0.1 1.9 1 0 0 1 1 1 1 AAA domain Dynamin_N PF00350.18 EGC37772.1 - 0.013 15.3 3.4 0.013 15.3 2.3 3.0 2 1 1 3 3 3 0 Dynamin family AAA_28 PF13521.1 EGC37772.1 - 0.022 14.7 0.0 0.06 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA domain DUF2195 PF09961.4 EGC37772.1 - 0.073 12.8 0.3 0.18 11.6 0.2 1.6 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2195) Laminin_EGF PF00053.19 EGC37773.1 - 0.0044 16.9 22.2 0.035 14.0 4.1 2.7 2 0 0 2 2 2 2 Laminin EGF-like (Domains III and V) WD40 PF00400.27 EGC37774.1 - 5.1e-21 73.7 1.1 9.1e-09 34.8 0.0 5.1 5 0 0 5 5 5 3 WD domain, G-beta repeat Coatomer_WDAD PF04053.9 EGC37774.1 - 2.8e-06 26.4 2.1 2.8e-06 26.4 1.5 1.7 2 0 0 2 2 2 1 Coatomer WD associated region Nucleoporin_N PF08801.6 EGC37774.1 - 0.00029 19.7 4.9 0.0016 17.2 2.0 2.5 1 1 1 2 2 2 2 Nup133 N terminal like Nup160 PF11715.3 EGC37774.1 - 0.002 16.3 0.3 0.03 12.4 0.1 2.6 1 1 1 2 2 2 1 Nucleoporin Nup120/160 cNMP_binding PF00027.24 EGC37774.1 - 0.059 13.1 0.0 0.25 11.1 0.0 2.1 1 0 0 1 1 1 0 Cyclic nucleotide-binding domain Arf PF00025.16 EGC37775.1 - 2.7e-48 163.5 0.0 3.5e-48 163.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGC37775.1 - 4.9e-18 64.9 1.7 1.7e-13 50.0 0.1 2.4 2 1 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGC37775.1 - 1.5e-10 40.7 0.0 1.8e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC37775.1 - 7.5e-09 36.1 0.0 1.5e-08 35.1 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein SRPRB PF09439.5 EGC37775.1 - 1e-08 34.6 0.0 1.3e-08 34.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Gtr1_RagA PF04670.7 EGC37775.1 - 1.6e-08 33.9 0.0 2e-08 33.6 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC37775.1 - 1.3e-05 25.0 0.1 4.4e-05 23.3 0.0 1.8 2 0 0 2 2 2 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC37775.1 - 0.00026 20.5 0.0 0.029 13.7 0.0 2.0 2 0 0 2 2 2 1 Elongation factor Tu GTP binding domain AAA_22 PF13401.1 EGC37775.1 - 0.0016 18.6 0.0 0.0032 17.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_23 PF13476.1 EGC37775.1 - 0.0053 17.1 1.7 0.011 16.1 1.2 1.6 1 1 0 1 1 1 1 AAA domain cobW PF02492.14 EGC37775.1 - 0.0082 15.6 1.1 0.23 10.8 0.1 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain ABC_tran PF00005.22 EGC37775.1 - 0.014 15.7 0.4 0.018 15.3 0.3 1.6 1 1 0 1 1 1 0 ABC transporter AAA_17 PF13207.1 EGC37775.1 - 0.014 16.2 0.2 0.038 14.7 0.2 1.7 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC37775.1 - 0.016 14.9 0.4 0.06 13.0 0.1 1.9 1 1 0 2 2 2 0 Archaeal ATPase NB-ARC PF00931.17 EGC37775.1 - 0.016 14.0 0.0 0.028 13.2 0.0 1.3 1 0 0 1 1 1 0 NB-ARC domain Thymidylate_kin PF02223.12 EGC37775.1 - 0.021 14.1 0.1 0.043 13.1 0.1 1.5 1 0 0 1 1 1 0 Thymidylate kinase NACHT PF05729.7 EGC37775.1 - 0.027 14.1 0.2 0.23 11.1 0.0 2.1 2 0 0 2 2 2 0 NACHT domain AAA_16 PF13191.1 EGC37775.1 - 0.051 13.5 0.0 0.071 13.0 0.0 1.7 1 1 0 1 1 1 0 AAA ATPase domain Zeta_toxin PF06414.7 EGC37775.1 - 0.052 12.6 0.0 0.15 11.1 0.0 1.7 2 0 0 2 2 2 0 Zeta toxin AAA_14 PF13173.1 EGC37775.1 - 0.065 13.1 0.4 0.18 11.6 0.1 1.8 1 1 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGC37775.1 - 0.067 12.7 0.0 4.9 6.6 0.0 2.1 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein SRP54 PF00448.17 EGC37775.1 - 0.091 12.1 0.1 0.21 11.0 0.1 1.6 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain AAA_28 PF13521.1 EGC37775.1 - 0.093 12.6 0.2 0.21 11.5 0.1 1.7 1 1 1 2 2 2 0 AAA domain Vmethyltransf PF01660.12 EGC37775.1 - 0.1 11.2 0.0 0.13 10.9 0.0 1.1 1 0 0 1 1 1 0 Viral methyltransferase AAA_33 PF13671.1 EGC37775.1 - 0.11 12.3 0.0 0.19 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC37775.1 - 0.14 12.5 0.2 0.26 11.5 0.1 1.5 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC37775.1 - 0.15 11.6 0.0 0.24 10.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain OTU PF02338.14 EGC37776.1 - 6e-12 46.2 0.0 6e-12 46.2 0.0 3.1 2 1 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC37776.1 - 3.8 5.6 75.0 5.1 5.2 52.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF572 PF04502.8 EGC37776.1 - 4.5 6.3 31.0 8.6 5.4 21.5 1.4 1 0 0 1 1 1 0 Family of unknown function (DUF572) DUF4094 PF13334.1 EGC37779.1 - 0.069 13.5 0.3 0.17 12.2 0.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) DUF2232 PF09991.4 EGC37779.1 - 0.15 11.0 3.0 0.25 10.2 2.1 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) zf-C4H2 PF10146.4 EGC37779.1 - 0.18 11.7 3.7 0.28 11.1 2.6 1.2 1 0 0 1 1 1 0 Zinc finger-containing protein Fib_alpha PF08702.5 EGC37779.1 - 0.68 10.0 5.1 1.3 9.0 3.5 1.4 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family RNA_pol_Rpb1_1 PF04997.7 EGC37780.1 - 7.2e-120 400.2 1.1 7.2e-120 400.2 0.8 1.6 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_5 PF04998.12 EGC37780.1 - 7.7e-106 353.3 0.0 7.7e-106 353.3 0.0 1.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_2 PF00623.15 EGC37780.1 - 4.2e-71 238.2 0.1 4.2e-71 238.2 0.0 2.7 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_6 PF04992.9 EGC37780.1 - 5.3e-60 202.3 0.1 9.9e-60 201.4 0.1 1.5 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 6 RNA_pol_Rpb1_3 PF04983.13 EGC37780.1 - 3.4e-52 176.3 0.0 7.3e-52 175.2 0.0 1.6 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_7 PF04990.7 EGC37780.1 - 1.3e-46 157.6 0.7 3.4e-46 156.2 0.5 1.8 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 7 RNA_pol_Rpb1_4 PF05000.12 EGC37780.1 - 3.5e-39 132.8 1.1 3.5e-39 132.8 0.7 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 4 RNA_pol_Rpb1_R PF05001.8 EGC37780.1 - 5.8e-15 54.0 319.7 0.039 14.0 9.2 16.3 4 1 18 25 25 25 22 RNA polymerase Rpb1 C-terminal repeat Pept_tRNA_hydro PF01195.14 EGC37781.1 - 3.4e-09 36.4 0.0 5.6e-09 35.7 0.0 1.3 1 1 0 1 1 1 1 Peptidyl-tRNA hydrolase TMEM154 PF15102.1 EGC37782.1 - 0.028 14.1 0.1 0.052 13.2 0.0 1.4 1 0 0 1 1 1 0 TMEM154 protein family RelA_SpoT PF04607.12 EGC37784.1 - 1.5e-10 41.0 1.2 3.7e-10 39.8 0.8 1.7 1 0 0 1 1 1 1 Region found in RelA / SpoT proteins FAM70 PF14967.1 EGC37784.1 - 0.2 10.8 0.8 0.28 10.3 0.5 1.2 1 0 0 1 1 1 0 FAM70 protein Myb_DNA-bind_6 PF13921.1 EGC37784.1 - 0.54 10.4 4.7 1.7 8.8 0.1 3.2 2 2 0 2 2 2 0 Myb-like DNA-binding domain FAD_binding_4 PF01565.18 EGC37785.1 - 2.4e-27 95.0 1.7 4.2e-27 94.3 0.5 1.9 2 0 0 2 2 2 1 FAD binding domain BBE PF08031.7 EGC37785.1 - 0.00083 19.2 1.3 0.0031 17.3 0.9 2.1 1 0 0 1 1 1 1 Berberine and berberine like YjeF_N PF03853.10 EGC37786.1 - 1.3e-36 125.7 0.0 1.5e-36 125.5 0.0 1.1 1 0 0 1 1 1 1 YjeF-related protein N-terminus HAD_2 PF13419.1 EGC37787.1 - 1.1e-10 42.0 0.1 5.1e-09 36.5 0.0 2.0 1 1 1 2 2 2 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGC37787.1 - 4.1e-05 23.2 0.0 6.6e-05 22.5 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Hydrolase PF00702.21 EGC37787.1 - 5.6e-05 23.6 0.1 0.32 11.3 0.1 2.1 1 1 0 2 2 2 2 haloacid dehalogenase-like hydrolase PNK3P PF08645.6 EGC37787.1 - 0.00037 19.9 0.0 0.00092 18.6 0.0 1.6 1 1 0 1 1 1 1 Polynucleotide kinase 3 phosphatase HAD PF12710.2 EGC37787.1 - 0.00074 19.7 0.0 0.0019 18.3 0.0 1.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Acid_PPase PF12689.2 EGC37787.1 - 0.0044 16.6 0.0 0.015 14.9 0.0 1.9 1 1 0 1 1 1 1 Acid Phosphatase BRCA2 PF00634.13 EGC37788.1 - 4.6e-07 28.9 3.8 0.0092 15.2 0.3 2.3 2 0 0 2 2 2 2 BRCA2 repeat DUF3657 PF12394.3 EGC37788.1 - 0.49 10.4 2.2 0.86 9.7 1.5 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF3657) Sod_Cu PF00080.15 EGC37789.1 - 2e-34 118.8 0.9 3.7e-25 88.7 1.2 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) CHRD PF07452.7 EGC37789.1 - 0.024 15.2 0.5 0.07 13.7 0.3 1.8 2 0 0 2 2 2 0 CHRD domain AF-4 PF05110.8 EGC37789.1 - 2.4 5.8 6.0 3.1 5.5 4.2 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein Sod_Cu PF00080.15 EGC37790.1 - 1.3e-32 112.8 1.0 3.7e-21 75.7 0.4 2.2 2 0 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) DNA_pol3_theta PF06440.6 EGC37791.1 - 0.063 12.8 3.0 0.12 11.9 2.1 1.4 1 0 0 1 1 1 0 DNA polymerase III, theta subunit GBV-C_env PF12786.2 EGC37791.1 - 0.12 10.7 0.3 0.11 10.8 0.2 1.2 1 0 0 1 1 1 0 GB virus C genotype envelope DUF4041 PF13250.1 EGC37792.1 - 0.059 12.9 4.9 3.6 7.2 0.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4041) NEMO PF11577.3 EGC37792.1 - 0.1 12.3 1.7 1.3 8.8 0.1 2.5 2 0 0 2 2 2 0 NF-kappa-B essential modulator NEMO Acetyltransf_7 PF13508.1 EGC37793.1 - 6.2e-06 26.2 0.0 1.4e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC37793.1 - 3.4e-05 23.6 0.0 7.6e-05 22.5 0.0 1.7 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC37793.1 - 7e-05 22.7 0.0 0.001 19.0 0.0 2.3 2 0 0 2 2 2 1 Acetyltransferase (GNAT) family Acetyltransf_CG PF14542.1 EGC37793.1 - 0.013 15.3 0.0 0.046 13.6 0.0 1.9 2 0 0 2 2 2 0 GCN5-related N-acetyl-transferase Acetyltransf_10 PF13673.1 EGC37793.1 - 0.028 14.5 0.0 0.072 13.2 0.0 1.8 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain OMPdecase PF00215.19 EGC37794.1 - 2.2e-75 252.9 0.3 3.2e-75 252.4 0.2 1.2 1 0 0 1 1 1 1 Orotidine 5'-phosphate decarboxylase / HUMPS family Pribosyltran PF00156.22 EGC37794.1 - 1.7e-10 40.7 0.5 7e-10 38.7 0.4 2.1 1 1 0 1 1 1 1 Phosphoribosyl transferase domain Glyco_hydro_63 PF03200.11 EGC37795.1 - 3.4e-226 752.8 25.5 4.3e-225 749.2 17.7 1.9 1 1 0 1 1 1 1 Mannosyl oligosaccharide glucosidase Trehalase PF01204.13 EGC37795.1 - 2.3e-07 29.8 0.3 3.7e-07 29.1 0.2 1.3 1 0 0 1 1 1 1 Trehalase Bac_rhamnosid PF05592.6 EGC37795.1 - 0.0014 16.9 0.0 0.0028 15.9 0.0 1.4 1 0 0 1 1 1 1 Bacterial alpha-L-rhamnosidase DUF4105 PF13387.1 EGC37796.1 - 0.056 12.6 2.2 0.078 12.1 0.8 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4105) DUF3634 PF12321.3 EGC37796.1 - 0.11 12.4 0.3 2.1 8.3 0.0 2.1 1 1 0 2 2 2 0 Protein of unknown function (DUF3634) F-box PF00646.28 EGC37796.1 - 0.64 9.7 2.8 1.5 8.5 0.1 2.7 3 0 0 3 3 3 0 F-box domain CIMR PF00878.13 EGC37797.1 - 0.0015 18.3 0.7 0.002 17.9 0.5 1.2 1 0 0 1 1 1 1 Cation-independent mannose-6-phosphate receptor repeat Ribonuc_L-PSP PF01042.16 EGC37801.1 - 4.2e-27 94.3 0.0 7.9e-27 93.4 0.0 1.4 1 1 0 1 1 1 1 Endoribonuclease L-PSP Gp_dh_C PF02800.15 EGC37802.1 - 1.7e-71 238.7 0.1 2.3e-71 238.3 0.1 1.2 1 0 0 1 1 1 1 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain Gp_dh_N PF00044.19 EGC37802.1 - 9.3e-59 197.7 1.0 2.5e-58 196.3 0.0 2.0 2 1 0 2 2 2 1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain DapB_N PF01113.15 EGC37802.1 - 0.0096 15.8 0.3 0.04 13.8 0.1 2.3 2 1 0 2 2 2 1 Dihydrodipicolinate reductase, N-terminus 2-Hacid_dh_C PF02826.14 EGC37802.1 - 0.12 11.5 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain Thioredoxin PF00085.15 EGC37803.1 - 9.7e-44 147.3 0.4 5.4e-33 112.7 0.3 3.3 3 0 0 3 3 3 3 Thioredoxin Thioredoxin_6 PF13848.1 EGC37803.1 - 2.6e-22 79.5 8.6 4.2e-10 39.7 0.2 3.2 2 1 1 3 3 3 3 Thioredoxin-like domain Thioredoxin_2 PF13098.1 EGC37803.1 - 8.3e-12 45.3 1.8 8.1e-06 26.0 0.3 3.7 3 1 0 3 3 3 3 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC37803.1 - 1.6e-11 44.1 1.1 5.6e-05 23.1 0.0 4.0 3 2 0 3 3 3 3 Thioredoxin-like Thioredoxin_7 PF13899.1 EGC37803.1 - 1.6e-05 24.7 0.1 0.0027 17.6 0.0 3.1 3 0 0 3 3 3 1 Thioredoxin-like HyaE PF07449.6 EGC37803.1 - 9.6e-05 22.2 0.0 3.1 7.7 0.0 3.6 3 1 0 3 3 3 2 Hydrogenase-1 expression protein HyaE AhpC-TSA PF00578.16 EGC37803.1 - 0.00079 19.1 0.4 0.0029 17.3 0.1 2.1 3 0 0 3 3 3 1 AhpC/TSA family Thioredoxin_5 PF13743.1 EGC37803.1 - 0.013 15.0 0.2 9.4 5.7 0.0 3.5 3 1 1 4 4 4 0 Thioredoxin Thioredoxin_3 PF13192.1 EGC37803.1 - 0.021 14.6 0.1 1.1 9.1 0.1 2.6 2 0 0 2 2 2 0 Thioredoxin domain Thioredoxin_9 PF14595.1 EGC37803.1 - 0.047 13.2 0.0 0.12 11.9 0.0 1.7 1 0 0 1 1 1 0 Thioredoxin DDE_Tnp_1_2 PF13586.1 EGC37803.1 - 0.1 12.7 0.0 0.22 11.7 0.0 1.5 1 0 0 1 1 1 0 Transposase DDE domain Thioredoxin PF00085.15 EGC37804.1 - 2.2e-26 91.5 0.6 3e-26 91.1 0.4 1.1 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGC37804.1 - 2.3e-08 34.1 0.3 1.6e-07 31.4 0.2 2.0 1 1 0 1 1 1 1 Thioredoxin-like domain AhpC-TSA PF00578.16 EGC37804.1 - 3.2e-05 23.6 0.3 3.8e-05 23.3 0.2 1.2 1 0 0 1 1 1 1 AhpC/TSA family Thioredoxin_8 PF13905.1 EGC37804.1 - 4.1e-05 23.6 0.3 0.0042 17.1 0.2 2.6 1 1 1 2 2 2 2 Thioredoxin-like Thioredoxin_9 PF14595.1 EGC37804.1 - 0.00067 19.2 0.8 0.00083 18.9 0.2 1.4 1 1 0 1 1 1 1 Thioredoxin Thioredoxin_3 PF13192.1 EGC37804.1 - 0.002 17.8 0.1 0.0036 17.0 0.0 1.3 1 0 0 1 1 1 1 Thioredoxin domain Thioredoxin_7 PF13899.1 EGC37804.1 - 0.0052 16.7 0.1 0.0091 16.0 0.1 1.5 1 0 0 1 1 1 1 Thioredoxin-like Redoxin PF08534.5 EGC37804.1 - 0.031 13.8 0.0 0.036 13.6 0.0 1.2 1 0 0 1 1 1 0 Redoxin DUF836 PF05768.9 EGC37804.1 - 0.086 13.1 0.2 0.12 12.6 0.2 1.4 1 0 0 1 1 1 0 Glutaredoxin-like domain (DUF836) zf-SAP30 PF13866.1 EGC37804.1 - 0.15 11.7 1.3 0.24 11.0 0.1 1.9 2 1 0 2 2 2 0 SAP30 zinc-finger Citrate_synt PF00285.16 EGC37805.1 - 2e-107 358.9 0.0 2.4e-107 358.7 0.0 1.0 1 0 0 1 1 1 1 Citrate synthase Proteasome PF00227.21 EGC37806.1 - 5.1e-60 202.0 0.2 9.7e-60 201.1 0.1 1.4 2 0 0 2 2 2 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC37806.1 - 8e-11 41.0 0.2 5.1e-10 38.4 0.0 2.1 2 0 0 2 2 2 1 Proteasome subunit A N-terminal signature Nuf2 PF03800.9 EGC37806.1 - 0.091 12.7 0.0 0.16 11.9 0.0 1.4 1 0 0 1 1 1 0 Nuf2 family FXa_inhibition PF14670.1 EGC37807.1 - 3.8e-120 391.6 257.9 8.5e-12 44.9 9.6 14.5 14 0 0 14 14 14 12 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EGC37807.1 - 2.6e-94 308.2 107.4 2.6e-09 36.5 1.3 14.1 14 0 0 14 14 14 12 Complement Clr-like EGF-like EGF_CA PF07645.10 EGC37807.1 - 3.8e-81 266.8 260.0 1.9e-08 34.1 7.9 14.7 15 0 0 15 15 15 13 Calcium-binding EGF domain EGF_3 PF12947.2 EGC37807.1 - 1.7e-42 143.0 246.9 2.1e-05 24.3 7.8 15.2 15 0 0 15 15 15 13 EGF domain EGF PF00008.22 EGC37807.1 - 7.3e-27 92.9 213.1 0.0059 16.5 4.4 14.6 14 0 0 14 14 14 12 EGF-like domain hEGF PF12661.2 EGC37807.1 - 1.1e-07 31.4 60.4 2.6 8.3 0.1 13.4 13 0 0 13 13 13 9 Human growth factor-like EGF EGF_2 PF07974.8 EGC37807.1 - 0.007 16.4 12.9 0.007 16.4 8.9 15.6 12 2 2 14 14 14 1 EGF-like domain OTU PF02338.14 EGC37808.1 - 9.3e-15 55.2 1.0 2.2e-14 54.0 0.0 2.2 2 0 0 2 2 2 1 OTU-like cysteine protease Trypan_PARP PF05887.6 EGC37808.1 - 0.12 12.1 0.0 18 5.1 0.0 2.3 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PAT1 PF09770.4 EGC37808.1 - 2 6.5 45.4 2.8 6.0 31.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 TFIIA PF03153.8 EGC37808.1 - 3.4 7.4 30.9 5.2 6.8 21.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit MAT1 PF06391.8 EGC37808.1 - 7.6 6.0 21.8 0.064 12.8 7.3 2.2 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 Med15 PF09606.5 EGC37808.1 - 8.8 4.3 45.7 11 4.0 31.7 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal zf-B_box PF00643.19 EGC37809.1 - 8.8e-05 22.3 3.2 8.8e-05 22.3 2.2 2.2 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.15 EGC37809.1 - 1.8 8.3 6.0 0.32 10.7 1.0 2.0 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) Fe_hyd_lg_C PF02906.9 EGC37809.1 - 8.3 5.5 7.2 2 7.6 1.4 2.0 2 0 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain FNIP PF05725.7 EGC37810.1 - 1.3e-66 220.2 35.3 1e-17 63.7 0.8 8.2 3 2 3 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 EGC37810.1 - 2.9e-06 27.1 15.3 3.5 7.6 0.0 8.7 2 2 8 10 10 10 5 Protein of unknown function (DUF1769) Helicase_C PF00271.26 EGC37811.1 - 9.3e-21 73.4 0.0 4.1e-19 68.2 0.0 2.9 3 0 0 3 3 3 1 Helicase conserved C-terminal domain DEAD PF00270.24 EGC37811.1 - 1.1e-19 70.4 0.0 2.7e-19 69.2 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase RQC PF09382.5 EGC37811.1 - 5e-14 51.9 0.5 1.2e-13 50.6 0.3 1.7 1 0 0 1 1 1 1 RQC domain ResIII PF04851.10 EGC37811.1 - 0.00016 21.5 0.0 0.00066 19.5 0.0 2.0 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit RNase_H_2 PF13482.1 EGC37811.1 - 0.014 15.1 1.6 0.89 9.3 0.0 2.8 2 1 1 3 3 3 0 RNase_H superfamily OTU PF02338.14 EGC37812.1 - 2e-14 54.2 2.6 2.3e-14 54.0 0.0 2.3 2 0 0 2 2 2 1 OTU-like cysteine protease Tetraspannin PF00335.15 EGC37812.1 - 0.11 11.7 1.8 0.18 11.0 1.2 1.3 1 0 0 1 1 1 0 Tetraspanin family TFIIA PF03153.8 EGC37812.1 - 2.6 7.8 30.1 3.9 7.2 20.8 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit PAT1 PF09770.4 EGC37812.1 - 4.2 5.4 45.6 5.7 5.0 31.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 MAT1 PF06391.8 EGC37812.1 - 6.1 6.3 22.4 0.077 12.5 9.0 2.1 1 1 1 2 2 2 0 CDK-activating kinase assembly factor MAT1 DUF1980 PF09323.5 EGC37812.1 - 8.4 6.0 7.5 3 7.5 1.1 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) FNIP PF05725.7 EGC37813.1 - 7.9e-36 121.7 54.7 2.2e-05 24.2 1.1 11.0 6 3 4 11 11 11 10 FNIP Repeat zf-B_box PF00643.19 EGC37813.1 - 0.0002 21.1 3.2 0.0002 21.1 2.2 1.9 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.15 EGC37813.1 - 1.9 8.2 4.6 0.68 9.6 0.9 1.8 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) FNIP PF05725.7 EGC37814.1 - 4.5e-23 80.9 27.8 6.5e-06 25.9 1.2 5.6 4 1 1 5 5 5 5 FNIP Repeat AftA_C PF12249.3 EGC37815.1 - 0.06 12.7 1.7 0.14 11.5 1.1 1.6 1 1 0 1 1 1 0 Arabinofuranosyltransferase A C terminal FNIP PF05725.7 EGC37816.1 - 4.9e-75 247.2 74.6 1.1e-14 54.0 0.5 10.5 5 3 6 12 12 12 11 FNIP Repeat DUF3689 PF12463.3 EGC37817.1 - 4.8e-19 68.2 21.2 1.6e-18 66.5 14.7 1.9 1 1 0 1 1 1 1 Protein of unknown function (DUF3689) SURF6 PF04935.7 EGC37818.1 - 3.7 6.7 12.8 0.31 10.3 4.9 1.9 2 0 0 2 2 2 0 Surfeit locus protein 6 GCD14 PF08704.5 EGC37818.1 - 6.2 6.2 9.4 1.2 8.5 3.8 1.7 2 0 0 2 2 2 0 tRNA methyltransferase complex GCD14 subunit Pex14_N PF04695.8 EGC37818.1 - 10 6.2 17.9 4.1 7.4 6.6 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUSP PF06337.7 EGC37819.1 - 2.1e-10 40.8 0.3 2.1e-10 40.8 0.2 5.0 4 1 0 4 4 4 1 DUSP domain CopK PF11525.3 EGC37819.1 - 0.16 11.6 0.8 5.4 6.7 0.1 2.4 2 0 0 2 2 2 0 Copper resistance protein K OTU PF02338.14 EGC37820.1 - 2.1e-13 50.8 0.2 4.5e-13 49.8 0.1 1.5 1 0 0 1 1 1 1 OTU-like cysteine protease DUF605 PF04652.11 EGC37820.1 - 0.025 13.9 51.3 0.033 13.5 35.6 1.1 1 0 0 1 1 1 0 Vta1 like DUF4551 PF15087.1 EGC37820.1 - 1.5 7.1 19.2 1.9 6.7 13.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF4551) DUSP PF06337.7 EGC37821.1 - 2.5e-10 40.6 0.6 2.5e-10 40.6 0.4 6.3 3 1 1 4 4 4 1 DUSP domain Glyco_transf_56 PF07429.6 EGC37822.1 - 0.01 14.8 0.2 0.012 14.6 0.1 1.0 1 0 0 1 1 1 0 4-alpha-L-fucosyltransferase glycosyl transferase group 56 Peptidase_S55 PF05580.7 EGC37822.1 - 0.082 12.3 1.4 0.083 12.3 1.0 1.0 1 0 0 1 1 1 0 SpoIVB peptidase S55 ERbeta_N PF12497.3 EGC37822.1 - 0.084 12.7 0.2 0.088 12.6 0.2 1.1 1 0 0 1 1 1 0 Estrogen receptor beta RRM_1 PF00076.17 EGC37823.1 - 3.7e-18 64.9 0.1 6e-18 64.2 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37823.1 - 1.5e-12 47.3 0.0 2.6e-12 46.5 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37823.1 - 1.9e-07 30.7 0.2 3.3e-07 30.0 0.1 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Menin PF05053.8 EGC37823.1 - 0.36 8.9 7.3 0.43 8.6 5.0 1.3 1 0 0 1 1 1 0 Menin CIA30 PF08547.7 EGC37824.1 - 1.4e-35 122.5 0.2 1.8e-35 122.1 0.1 1.1 1 0 0 1 1 1 1 Complex I intermediate-associated protein 30 (CIA30) CBM_11 PF03425.8 EGC37824.1 - 1e-05 25.3 0.3 1.9e-05 24.4 0.2 1.4 1 1 0 1 1 1 1 Carbohydrate binding domain (family 11) DUF4168 PF13767.1 EGC37824.1 - 0.035 14.7 0.0 0.39 11.3 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4168) DEAD PF00270.24 EGC37825.1 - 1e-40 138.9 0.1 1e-40 138.9 0.1 2.8 3 0 0 3 3 3 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC37825.1 - 8.2e-29 99.2 1.0 4.6e-26 90.4 0.2 2.7 2 0 0 2 2 2 2 Helicase conserved C-terminal domain PA14 PF07691.7 EGC37826.1 - 4.5e-14 52.3 0.4 7.8e-14 51.5 0.3 1.4 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC37826.1 - 0.0052 16.6 3.0 0.0052 16.6 2.0 11.0 11 0 0 11 11 11 3 Dictyostelium (slime mold) repeat PA14 PF07691.7 EGC37827.1 - 1.2e-10 41.1 0.2 2.9e-10 39.9 0.2 1.6 1 0 0 1 1 1 1 PA14 domain PA14 PF07691.7 EGC37828.1 - 3.3e-20 72.2 0.4 6.5e-20 71.2 0.1 1.7 2 0 0 2 2 2 1 PA14 domain Dicty_CTDC PF00526.13 EGC37828.1 - 0.0016 18.2 7.9 0.0016 18.2 5.5 12.7 12 2 1 13 13 13 4 Dictyostelium (slime mold) repeat DUF1764 PF08576.5 EGC37830.1 - 5.6e-07 30.2 8.1 5.6e-07 30.2 5.6 2.2 1 1 1 2 2 2 1 Eukaryotic protein of unknown function (DUF1764) SOBP PF15279.1 EGC37830.1 - 0.78 10.0 5.5 0.88 9.9 3.8 1.1 1 0 0 1 1 1 0 Sine oculis-binding protein Lyase_catalyt PF09093.6 EGC37830.1 - 2.6 6.8 7.7 0.063 12.1 0.6 1.6 2 0 0 2 2 2 0 Lyase, catalytic SR-25 PF10500.4 EGC37830.1 - 3.6 7.0 22.0 5.6 6.3 15.3 1.3 1 1 0 1 1 1 0 Nuclear RNA-splicing-associated protein Pkinase PF00069.20 EGC37832.1 - 9.8e-57 192.0 0.0 2.3e-56 190.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37832.1 - 1.1e-51 175.4 0.0 1.8e-51 174.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC37832.1 - 0.011 14.8 0.0 0.02 13.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family 2-oxoacid_dh PF00198.18 EGC37833.1 - 2.9e-82 275.4 0.0 3.5e-82 275.1 0.0 1.1 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGC37833.1 - 1.5e-18 66.1 2.1 3e-18 65.2 1.5 1.5 1 0 0 1 1 1 1 Biotin-requiring enzyme HlyD_2 PF12700.2 EGC37833.1 - 1.9e-05 24.0 0.0 0.00044 19.5 0.0 2.3 1 1 1 2 2 2 1 HlyD family secretion protein GCV_H PF01597.14 EGC37833.1 - 6e-05 22.7 0.4 0.00018 21.1 0.2 1.8 1 1 0 1 1 1 1 Glycine cleavage H-protein Biotin_lipoyl_2 PF13533.1 EGC37833.1 - 0.012 15.2 0.0 0.012 15.2 0.0 2.2 3 0 0 3 3 3 0 Biotin-lipoyl like RnfC_N PF13375.1 EGC37833.1 - 0.016 14.9 0.1 0.044 13.5 0.1 1.8 1 0 0 1 1 1 0 RnfC Barrel sandwich hybrid domain HlyD_3 PF13437.1 EGC37833.1 - 0.017 15.4 0.3 0.14 12.4 0.0 2.3 1 1 1 2 2 2 0 HlyD family secretion protein KxDL PF10241.4 EGC37833.1 - 0.033 14.0 0.9 0.061 13.2 0.6 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein CsrA PF02599.11 EGC37833.1 - 0.28 10.9 2.5 4.3 7.1 0.2 3.2 3 0 0 3 3 3 0 Global regulator protein family Neisseria_TspB PF05616.8 EGC37833.1 - 0.32 9.2 4.4 0.44 8.8 3.0 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein Hc1 PF07432.8 EGC37833.1 - 1.3 9.2 10.4 2.8 8.1 7.2 1.6 1 0 0 1 1 1 0 Histone H1-like protein Hc1 DUF2360 PF10152.4 EGC37833.1 - 1.9 8.7 6.2 3.3 7.9 4.3 1.4 1 0 0 1 1 1 0 Predicted coiled-coil domain-containing protein (DUF2360) DUF3275 PF11679.3 EGC37833.1 - 2.2 7.8 5.2 3.7 7.1 3.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3275) Glyoxalase_4 PF13669.1 EGC37834.1 - 4.7e-19 68.4 0.0 5.7e-19 68.1 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase PF00903.20 EGC37834.1 - 1.5e-12 47.5 0.0 1.7e-12 47.3 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_2 PF12681.2 EGC37834.1 - 3.7e-08 33.9 0.0 4.4e-08 33.7 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGC37834.1 - 8.3e-05 22.5 0.0 0.0001 22.2 0.0 1.1 1 0 0 1 1 1 1 Glyoxalase-like domain Rab3-GTPase_cat PF13890.1 EGC37835.1 - 2.3e-39 134.4 2.1 2.1e-38 131.2 1.5 2.4 1 1 0 1 1 1 1 Rab3 GTPase-activating protein catalytic subunit zf-UBR PF02207.15 EGC37836.1 - 6.1e-19 67.5 14.7 2.1e-18 65.7 10.2 2.0 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Ribosomal_S8 PF00410.14 EGC37836.1 - 5.7e-11 42.3 0.0 2e-10 40.5 0.0 2.0 1 0 0 1 1 1 1 Ribosomal protein S8 zf-RING_2 PF13639.1 EGC37836.1 - 0.00011 21.9 0.3 0.00011 21.9 0.2 3.4 4 0 0 4 4 4 1 Ring finger domain zf-RING_5 PF14634.1 EGC37836.1 - 0.0083 15.8 0.1 0.0083 15.8 0.1 2.9 2 0 0 2 2 2 1 zinc-RING finger domain MatE PF01554.13 EGC37837.1 - 7.8e-49 165.4 16.3 2.9e-35 121.2 5.3 2.5 2 0 0 2 2 2 2 MatE Polysacc_synt_C PF14667.1 EGC37837.1 - 0.00011 22.0 15.1 0.00046 20.0 2.7 3.5 4 1 0 4 4 4 2 Polysaccharide biosynthesis C-terminal domain MatE PF01554.13 EGC37838.1 - 8.2e-64 214.1 25.0 4e-35 120.8 5.3 2.4 2 0 0 2 2 2 2 MatE SNARE PF05739.14 EGC37839.1 - 6.6e-12 44.9 10.6 3.8e-07 29.7 3.1 2.6 2 0 0 2 2 2 2 SNARE domain GRAM PF02893.15 EGC37839.1 - 6.3e-10 38.4 0.1 1.2e-09 37.5 0.1 1.5 1 0 0 1 1 1 1 GRAM domain V-SNARE_C PF12352.3 EGC37839.1 - 2.6e-08 33.8 6.7 7.1e-08 32.4 0.4 2.7 2 1 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus Perilipin PF03036.11 EGC37839.1 - 0.014 14.2 0.2 3 6.5 0.1 2.1 2 0 0 2 2 2 0 Perilipin family Fib_alpha PF08702.5 EGC37839.1 - 1.9 8.6 6.8 17 5.4 0.1 3.0 2 1 1 3 3 3 0 Fibrinogen alpha/beta chain family Ank_2 PF12796.2 EGC37840.1 - 0.00016 21.9 0.0 0.17 12.2 0.0 3.7 1 1 0 1 1 1 1 Ankyrin repeats (3 copies) GDPD PF03009.12 EGC37841.1 - 4.8e-39 134.4 0.0 1.1e-38 133.1 0.0 1.6 1 1 0 1 1 1 1 Glycerophosphoryl diester phosphodiesterase family GDPD_2 PF13653.1 EGC37841.1 - 0.0013 18.8 0.1 0.13 12.4 0.0 2.4 2 0 0 2 2 2 1 Glycerophosphoryl diester phosphodiesterase family TRAM_LAG1_CLN8 PF03798.11 EGC37841.1 - 0.22 11.0 6.1 0.22 11.0 0.1 2.4 3 0 0 3 3 3 0 TLC domain Cpn60_TCP1 PF00118.19 EGC37843.1 - 7.8e-86 288.6 18.0 1.2e-85 287.9 12.5 1.3 1 1 0 1 1 1 1 TCP-1/cpn60 chaperonin family APC10 PF03256.11 EGC37844.1 - 0.0011 18.5 0.0 0.52 9.8 0.0 2.5 2 0 0 2 2 2 2 Anaphase-promoting complex, subunit 10 (APC10) SUA5 PF03481.8 EGC37844.1 - 0.0085 16.1 2.4 4 7.5 0.0 3.8 2 2 0 2 2 2 2 Putative GTP-binding controlling metal-binding TMEM223 PF14640.1 EGC37844.1 - 0.5 10.2 10.4 1.7 8.5 0.1 3.5 3 1 1 4 4 4 0 Transmembrane protein 223 Copine PF07002.11 EGC37845.1 - 1.8e-39 134.7 0.7 4.4e-39 133.5 0.1 1.9 2 0 0 2 2 2 1 Copine C2 PF00168.25 EGC37845.1 - 2.6e-20 72.0 0.1 3.8e-10 39.4 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC37845.1 - 3.4e-08 33.5 0.0 6.1e-08 32.7 0.0 1.3 1 0 0 1 1 1 1 vWA found in TerF C terminus VWA PF00092.23 EGC37845.1 - 0.00014 21.6 0.3 0.00034 20.3 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC37845.1 - 0.11 12.6 0.0 0.18 11.9 0.0 1.4 1 0 0 1 1 1 0 von Willebrand factor type A domain DUF4419 PF14388.1 EGC37846.1 - 2e-90 303.0 5.0 2.2e-90 302.8 3.5 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) Rsbr_N PF08678.5 EGC37846.1 - 0.028 14.2 0.0 0.89 9.4 0.0 2.6 2 0 0 2 2 2 0 Rsbr N terminal TIG PF01833.19 EGC37847.1 - 2.4e-07 30.6 16.0 0.00021 21.2 0.2 4.8 5 0 0 5 5 5 2 IPT/TIG domain LRR_8 PF13855.1 EGC37847.1 - 2.1e-06 27.3 14.1 0.016 14.9 0.3 5.2 3 1 1 4 4 4 3 Leucine rich repeat EGF_2 PF07974.8 EGC37847.1 - 0.00023 21.2 28.1 0.0095 16.0 8.0 2.7 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.19 EGC37847.1 - 0.016 15.1 2.5 0.016 15.1 1.8 2.5 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC37847.1 - 0.42 10.8 7.1 0.21 11.7 0.9 2.6 2 0 0 2 2 2 0 Human growth factor-like EGF LRR_4 PF12799.2 EGC37847.1 - 4.1 7.1 38.6 0.05 13.2 0.3 6.5 5 1 1 6 6 6 0 Leucine Rich repeats (2 copies) GST_N_2 PF13409.1 EGC37848.1 - 5.5e-21 74.3 0.0 1.1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC37848.1 - 2.9e-15 55.8 0.0 5.7e-15 54.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC37848.1 - 1.6e-08 34.3 0.1 2.8e-08 33.6 0.1 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC37848.1 - 3e-07 30.8 0.0 5.1e-07 30.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC37848.1 - 0.0004 20.5 0.0 0.015 15.5 0.0 2.5 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC37849.1 - 9e-11 41.6 0.0 1.4e-10 41.0 0.0 1.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC37850.1 - 6.5e-17 61.2 0.0 1e-16 60.6 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC37850.1 - 4.7e-08 32.8 0.0 7.1e-08 32.2 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC37850.1 - 3e-06 27.3 0.0 0.00013 22.1 0.0 2.3 1 1 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_C_3 PF14497.1 EGC37850.1 - 0.00021 21.7 0.0 0.00073 19.9 0.0 1.9 1 1 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC37850.1 - 0.0022 17.9 0.1 0.0062 16.4 0.1 1.8 1 1 1 2 2 2 1 Glutathione S-transferase, C-terminal domain AAA_2 PF07724.9 EGC37851.1 - 5.3e-60 202.2 0.1 1.7e-55 187.5 0.0 3.0 3 0 0 3 3 2 2 AAA domain (Cdc48 subfamily) AAA PF00004.24 EGC37851.1 - 2.9e-27 95.4 0.0 4.6e-14 52.7 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) ClpB_D2-small PF10431.4 EGC37851.1 - 1.2e-21 76.3 0.5 1.2e-21 76.3 0.4 3.6 4 0 0 4 4 3 1 C-terminal, D2-small domain, of ClpB protein Clp_N PF02861.15 EGC37851.1 - 3.8e-20 71.5 2.9 1.6e-09 37.5 0.1 3.0 2 0 0 2 2 2 2 Clp amino terminal domain AAA_5 PF07728.9 EGC37851.1 - 1.1e-18 67.3 1.3 6.9e-12 45.2 0.0 4.2 4 1 0 4 4 4 2 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC37851.1 - 8e-17 61.8 1.4 4.2e-06 26.8 0.0 4.5 3 2 1 5 5 5 2 AAA ATPase domain AAA_22 PF13401.1 EGC37851.1 - 6.5e-11 42.4 0.9 0.0027 17.8 0.0 5.3 3 2 1 4 4 4 2 AAA domain Sigma54_activat PF00158.21 EGC37851.1 - 1e-10 41.3 0.1 5.3e-07 29.2 0.0 3.2 3 1 0 3 3 3 2 Sigma-54 interaction domain AAA_14 PF13173.1 EGC37851.1 - 1.5e-08 34.5 0.0 0.0032 17.3 0.0 2.9 2 0 0 2 2 2 2 AAA domain AAA_17 PF13207.1 EGC37851.1 - 2.5e-08 34.7 5.1 0.0042 17.8 0.0 4.2 3 2 0 4 4 3 2 AAA domain IstB_IS21 PF01695.12 EGC37851.1 - 3.6e-08 33.0 0.0 0.0034 16.8 0.0 2.8 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_18 PF13238.1 EGC37851.1 - 8e-08 32.6 1.0 0.031 14.5 0.0 3.6 3 0 0 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EGC37851.1 - 1.8e-06 27.8 2.1 0.11 12.2 0.2 4.5 3 2 0 3 3 2 2 Archaeal ATPase AAA_23 PF13476.1 EGC37851.1 - 2.9e-06 27.7 6.9 0.0061 16.8 0.1 3.4 3 0 0 3 3 3 2 AAA domain Zeta_toxin PF06414.7 EGC37851.1 - 1.6e-05 24.1 0.0 0.0022 17.1 0.0 3.0 3 1 0 3 3 3 1 Zeta toxin RuvB_N PF05496.7 EGC37851.1 - 2.9e-05 23.2 1.3 0.06 12.3 0.0 3.8 3 1 0 3 3 3 1 Holliday junction DNA helicase ruvB N-terminus NACHT PF05729.7 EGC37851.1 - 5.8e-05 22.8 0.0 0.2 11.3 0.0 2.8 2 0 0 2 2 2 2 NACHT domain AAA_19 PF13245.1 EGC37851.1 - 0.00013 21.6 0.0 0.12 12.1 0.0 3.0 2 0 0 2 2 2 1 Part of AAA domain AAA_25 PF13481.1 EGC37851.1 - 0.00014 21.3 0.0 0.74 9.1 0.0 3.1 2 0 0 2 2 2 2 AAA domain RNA_helicase PF00910.17 EGC37851.1 - 0.00017 21.7 0.0 0.94 9.6 0.0 3.3 3 0 0 3 3 3 2 RNA helicase DNA_pol3_delta2 PF13177.1 EGC37851.1 - 0.00021 20.9 0.1 0.012 15.2 0.0 3.5 4 2 1 5 5 3 1 DNA polymerase III, delta subunit AAA_28 PF13521.1 EGC37851.1 - 0.00026 21.0 0.4 2.7 7.9 0.0 3.9 3 1 0 3 3 3 2 AAA domain ABC_tran PF00005.22 EGC37851.1 - 0.00049 20.4 1.1 0.29 11.4 0.0 4.0 3 1 0 3 3 3 1 ABC transporter Mg_chelatase PF01078.16 EGC37851.1 - 0.00054 19.1 0.0 1.1 8.3 0.0 3.5 2 1 0 2 2 2 1 Magnesium chelatase, subunit ChlI AAA_3 PF07726.6 EGC37851.1 - 0.0017 17.9 0.1 1 8.9 0.0 3.3 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) DUF87 PF01935.12 EGC37851.1 - 0.0017 18.2 5.4 0.26 11.0 0.0 4.1 4 0 0 4 4 4 1 Domain of unknown function DUF87 T2SE PF00437.15 EGC37851.1 - 0.0018 17.2 0.0 0.013 14.3 0.0 2.3 2 0 0 2 2 2 1 Type II/IV secretion system protein DUF258 PF03193.11 EGC37851.1 - 0.0027 16.8 0.0 2.9 7.0 0.0 2.9 2 1 0 2 2 2 1 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC37851.1 - 0.0056 16.5 0.0 1.6 8.6 0.0 2.9 2 0 0 2 2 2 1 AAA domain MMR_HSR1 PF01926.18 EGC37851.1 - 0.0072 16.2 0.0 2.6 8.0 0.0 3.4 2 1 0 2 2 2 1 50S ribosome-binding GTPase UPF0079 PF02367.12 EGC37851.1 - 0.0078 15.8 0.0 11 5.6 0.0 3.5 3 0 0 3 3 3 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EGC37851.1 - 0.01 15.4 0.0 2 7.9 0.0 2.7 2 0 0 2 2 2 0 AAA domain MobB PF03205.9 EGC37851.1 - 0.014 15.0 0.0 3.8 7.2 0.0 2.8 3 0 0 3 3 2 0 Molybdopterin guanine dinucleotide synthesis protein B ResIII PF04851.10 EGC37851.1 - 0.016 15.0 0.0 2.9 7.6 0.0 3.6 2 1 0 2 2 2 0 Type III restriction enzyme, res subunit AAA_29 PF13555.1 EGC37851.1 - 0.028 13.9 0.0 9.8 5.7 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain SRP54 PF00448.17 EGC37851.1 - 0.039 13.4 0.1 12 5.3 0.0 3.5 3 0 0 3 3 3 0 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EGC37851.1 - 0.11 11.9 3.8 0.9 8.9 0.0 3.3 3 2 1 4 4 4 0 AAA-like domain IncA PF04156.9 EGC37851.1 - 0.68 9.4 15.5 0.068 12.7 7.0 2.1 2 0 0 2 2 1 0 IncA protein FAD_binding_3 PF01494.14 EGC37853.1 - 1.2e-18 67.3 0.0 3.1e-18 65.9 0.0 1.6 1 1 0 1 1 1 1 FAD binding domain NAD_binding_8 PF13450.1 EGC37853.1 - 0.00039 20.3 0.0 0.00081 19.3 0.0 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain SE PF08491.5 EGC37853.1 - 0.0032 16.3 0.0 0.018 13.8 0.0 1.9 2 0 0 2 2 2 1 Squalene epoxidase Thi4 PF01946.12 EGC37853.1 - 0.051 12.6 0.0 0.09 11.8 0.0 1.4 1 0 0 1 1 1 0 Thi4 family NAD_binding_9 PF13454.1 EGC37853.1 - 0.072 12.8 0.0 0.15 11.7 0.0 1.5 1 0 0 1 1 1 0 FAD-NAD(P)-binding Pyr_redox_3 PF13738.1 EGC37853.1 - 0.12 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase F420_oxidored PF03807.12 EGC37853.1 - 0.15 12.5 0.1 0.36 11.2 0.0 1.6 2 0 0 2 2 2 0 NADP oxidoreductase coenzyme F420-dependent Amidohydro_2 PF04909.9 EGC37854.1 - 5.2e-27 95.1 0.0 7.3e-27 94.6 0.0 1.2 1 0 0 1 1 1 1 Amidohydrolase Calci_bind_CcbP PF11535.3 EGC37854.1 - 0.067 13.4 0.0 0.2 11.9 0.0 1.8 2 0 0 2 2 2 0 Calcium binding Tox-REase-3 PF15647.1 EGC37854.1 - 0.081 12.7 0.2 0.95 9.2 0.0 2.6 2 1 1 3 3 3 0 Restriction endonuclease fold toxin 3 SLA_LP_auto_ag PF05889.8 EGC37855.1 - 1.4e-127 425.4 0.0 4e-127 423.8 0.0 1.6 1 1 0 1 1 1 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) Beta_elim_lyase PF01212.16 EGC37855.1 - 7e-05 22.1 0.0 9.5e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Beta-eliminating lyase Med22 PF06179.7 EGC37856.1 - 2.2e-29 101.6 8.5 2.8e-29 101.3 5.9 1.1 1 0 0 1 1 1 1 Surfeit locus protein 5 subunit 22 of Mediator complex Myb_DNA-bind_6 PF13921.1 EGC37856.1 - 0.0068 16.4 0.9 0.024 14.7 0.1 2.1 2 0 0 2 2 2 1 Myb-like DNA-binding domain PMC2NT PF08066.7 EGC37856.1 - 0.038 14.2 0.9 0.093 13.0 0.1 1.9 1 1 1 2 2 2 0 PMC2NT (NUC016) domain DUF2653 PF10850.3 EGC37856.1 - 0.095 13.0 0.7 5.8 7.2 0.0 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF2653) OHCU_decarbox PF09349.5 EGC37856.1 - 0.096 12.9 0.3 0.12 12.7 0.2 1.2 1 0 0 1 1 1 0 OHCU decarboxylase CemA PF03040.9 EGC37856.1 - 0.72 9.4 8.3 0.21 11.1 2.3 1.9 1 1 1 2 2 2 0 CemA family DUF1084 PF06454.6 EGC37857.1 - 2.2e-13 49.8 26.9 5.4e-13 48.6 18.7 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF1084) NmrA PF05368.8 EGC37858.1 - 1.4e-37 129.1 0.0 1.8e-37 128.8 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC37858.1 - 4.3e-14 52.9 0.0 5.7e-14 52.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC37858.1 - 1.4e-07 30.5 0.0 3.9e-07 29.0 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family KR PF08659.5 EGC37858.1 - 0.00032 20.4 0.0 0.0016 18.0 0.0 1.9 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGC37858.1 - 0.00041 20.2 0.0 0.002 18.0 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase Epimerase PF01370.16 EGC37858.1 - 0.0015 18.0 0.0 0.004 16.6 0.0 1.6 1 1 1 2 2 2 1 NAD dependent epimerase/dehydratase family DapB_N PF01113.15 EGC37858.1 - 0.027 14.3 0.7 0.043 13.7 0.1 1.6 2 0 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Semialdhyde_dh PF01118.19 EGC37858.1 - 0.035 14.3 0.0 0.13 12.5 0.0 2.0 1 1 1 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain F420_oxidored PF03807.12 EGC37858.1 - 0.073 13.5 0.1 0.14 12.6 0.1 1.5 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent TAFII55_N PF04658.8 EGC37859.1 - 5.1e-41 139.8 1.4 5.1e-41 139.8 0.9 2.0 2 0 0 2 2 2 1 TAFII55 protein conserved region IncA PF04156.9 EGC37859.1 - 6.4 6.3 10.8 0.25 10.9 2.7 2.0 2 0 0 2 2 2 0 IncA protein VMA21 PF09446.5 EGC37860.1 - 4e-08 33.0 3.9 5.5e-08 32.6 2.7 1.2 1 0 0 1 1 1 1 VMA21-like domain GET2 PF08690.5 EGC37860.1 - 0.037 13.2 4.2 0.056 12.6 2.9 1.3 1 0 0 1 1 1 0 GET complex subunit GET2 TFIIF_alpha PF05793.7 EGC37860.1 - 0.13 10.6 28.1 0.16 10.3 19.4 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) ORC6 PF05460.8 EGC37860.1 - 0.46 9.5 13.6 0.62 9.1 9.4 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) Ndc1_Nup PF09531.5 EGC37860.1 - 1.2 7.5 8.3 1.5 7.1 5.8 1.3 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ycf1 PF05758.7 EGC37860.1 - 1.8 6.1 12.2 2.3 5.8 8.4 1.1 1 0 0 1 1 1 0 Ycf1 FAM220 PF15487.1 EGC37860.1 - 5.6 6.2 13.6 7.8 5.7 9.4 1.1 1 0 0 1 1 1 0 FAM220 family Pex16 PF08610.5 EGC37860.1 - 7.1 5.5 10.4 40 3.0 6.2 2.0 1 1 1 2 2 2 0 Peroxisomal membrane protein (Pex16) Pyr_redox_2 PF07992.9 EGC37861.1 - 9.8e-43 146.3 4.3 2.4e-42 145.0 3.0 2.2 1 1 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_dim PF02852.17 EGC37861.1 - 2.6e-40 136.8 0.1 8e-40 135.2 0.1 1.9 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain Pyr_redox PF00070.22 EGC37861.1 - 1.2e-22 80.0 10.0 1.1e-18 67.4 0.7 3.1 3 0 0 3 3 2 2 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC37861.1 - 3.3e-09 36.3 0.4 3.3e-09 36.3 0.3 2.4 2 1 0 2 2 2 1 FAD dependent oxidoreductase GIDA PF01134.17 EGC37861.1 - 1.4e-08 34.0 9.7 5.3e-08 32.1 2.5 2.7 2 1 1 3 3 3 1 Glucose inhibited division protein A Pyr_redox_3 PF13738.1 EGC37861.1 - 1.5e-08 34.9 7.0 6.2e-05 23.1 1.2 2.5 1 1 0 2 2 2 2 Pyridine nucleotide-disulphide oxidoreductase HI0933_like PF03486.9 EGC37861.1 - 5e-07 28.5 13.6 0.00011 20.8 1.8 3.8 3 1 1 4 4 4 2 HI0933-like protein NAD_binding_8 PF13450.1 EGC37861.1 - 1.1e-06 28.6 3.7 0.00016 21.6 1.0 2.6 2 0 0 2 2 2 1 NAD(P)-binding Rossmann-like domain FAD_binding_2 PF00890.19 EGC37861.1 - 3.1e-06 26.3 19.6 5.5e-06 25.4 2.1 4.2 3 1 2 5 5 5 2 FAD binding domain Thi4 PF01946.12 EGC37861.1 - 8.1e-05 21.8 10.2 0.0057 15.7 3.6 3.0 1 1 1 2 2 2 2 Thi4 family Lycopene_cycl PF05834.7 EGC37861.1 - 0.00015 20.8 3.9 0.22 10.3 0.0 3.0 2 1 1 3 3 3 2 Lycopene cyclase protein K_oxygenase PF13434.1 EGC37861.1 - 0.00033 19.6 4.4 0.0086 15.0 0.1 2.6 3 0 0 3 3 3 2 L-lysine 6-monooxygenase (NADPH-requiring) DAO PF01266.19 EGC37861.1 - 0.00049 19.1 18.4 0.016 14.1 0.7 4.1 3 1 1 4 4 4 3 FAD dependent oxidoreductase AlaDh_PNT_C PF01262.16 EGC37861.1 - 0.0096 15.5 3.0 1.8 8.1 0.1 2.7 2 0 0 2 2 2 2 Alanine dehydrogenase/PNT, C-terminal domain 3HCDH_N PF02737.13 EGC37861.1 - 0.012 15.2 0.3 0.012 15.2 0.2 2.3 3 0 0 3 3 3 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain XdhC_C PF13478.1 EGC37861.1 - 0.016 15.4 0.0 5.5 7.2 0.0 2.6 2 0 0 2 2 2 0 XdhC Rossmann domain NAD_binding_7 PF13241.1 EGC37861.1 - 0.04 14.1 1.5 0.98 9.7 0.1 2.7 2 0 0 2 2 2 0 Putative NAD(P)-binding Amino_oxidase PF01593.19 EGC37861.1 - 0.066 12.2 5.2 1.2 8.1 0.2 2.7 3 0 0 3 3 3 0 Flavin containing amine oxidoreductase Mqo PF06039.10 EGC37861.1 - 0.095 10.8 4.9 0.43 8.7 0.1 2.5 2 1 1 3 3 3 0 Malate:quinone oxidoreductase (Mqo) FAD_binding_3 PF01494.14 EGC37861.1 - 0.72 8.8 14.5 0.019 14.0 1.8 3.1 3 1 1 4 4 4 0 FAD binding domain FNIP PF05725.7 EGC37862.1 - 4.3e-48 161.0 15.2 2.6e-14 52.8 0.1 6.2 6 0 0 6 6 6 6 FNIP Repeat LRR_5 PF13306.1 EGC37862.1 - 3.6e-05 23.4 6.4 0.04 13.6 0.4 2.7 3 0 0 3 3 3 2 Leucine rich repeats (6 copies) XisH PF08814.5 EGC37864.1 - 0.0033 17.4 0.3 0.03 14.3 0.0 2.2 2 1 0 2 2 2 1 XisH protein Ribosomal_L27e PF01777.13 EGC37866.1 - 1.1e-26 92.7 3.6 1.4e-26 92.4 2.5 1.1 1 0 0 1 1 1 1 Ribosomal L27e protein family zf-RING_2 PF13639.1 EGC37867.1 - 8e-14 51.2 8.5 1.2e-13 50.6 5.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC37867.1 - 2e-06 27.3 10.2 3.2e-06 26.7 7.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37867.1 - 2.3e-06 27.5 9.4 3.5e-06 26.9 6.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37867.1 - 1.2e-05 25.2 10.0 2.8e-05 24.1 6.9 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC37867.1 - 7.9e-05 22.2 5.0 0.00011 21.7 3.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC37867.1 - 0.00032 20.3 8.8 0.00048 19.7 6.1 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC37867.1 - 0.00097 18.9 6.3 0.0025 17.6 4.3 1.7 1 1 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGC37867.1 - 0.0012 18.8 6.9 0.0024 17.8 4.8 1.5 1 1 0 1 1 1 1 RING-variant domain zf-RING_UBOX PF13445.1 EGC37867.1 - 0.0062 16.2 4.9 0.012 15.3 3.4 1.4 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGC37867.1 - 0.21 11.1 8.8 0.38 10.3 6.1 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-P11 PF03854.9 EGC37867.1 - 0.24 10.9 9.1 0.66 9.5 6.3 1.7 1 1 0 1 1 1 0 P-11 zinc finger zf-C3HC4_4 PF15227.1 EGC37867.1 - 0.48 10.3 5.9 0.98 9.3 4.1 1.5 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING FANCL_C PF11793.3 EGC37867.1 - 0.65 10.0 8.6 1.8 8.5 5.9 1.8 1 1 0 1 1 1 0 FANCL C-terminal domain zf-RING-like PF08746.6 EGC37867.1 - 3.1 7.8 8.5 5.7 7.0 5.9 1.5 1 1 0 1 1 1 0 RING-like domain FNIP PF05725.7 EGC37868.1 - 1.4e-17 63.3 18.1 2.6e-07 30.4 0.6 4.3 1 1 3 4 4 4 4 FNIP Repeat Pkinase PF00069.20 EGC37869.1 - 1.2e-35 122.9 0.1 1.6e-35 122.5 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain FNIP PF05725.7 EGC37869.1 - 1.3e-34 117.8 2.3 6.6e-09 35.5 0.3 7.2 4 3 3 7 7 7 6 FNIP Repeat Pkinase_Tyr PF07714.12 EGC37869.1 - 2e-19 69.6 0.0 2.8e-19 69.2 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC37869.1 - 0.00022 20.3 0.3 0.0005 19.2 0.2 1.5 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC37869.1 - 0.0085 15.0 0.0 0.018 14.0 0.0 1.5 1 0 0 1 1 1 1 Kinase-like RIO1 PF01163.17 EGC37869.1 - 0.022 14.1 0.2 0.042 13.2 0.1 1.5 1 0 0 1 1 1 0 RIO1 family APH PF01636.18 EGC37869.1 - 0.091 12.4 0.1 0.28 10.8 0.0 1.6 2 0 0 2 2 2 0 Phosphotransferase enzyme family Claudin_2 PF13903.1 EGC37870.1 - 0.00019 21.1 0.6 0.00019 21.1 0.4 2.0 2 0 0 2 2 2 1 PMP-22/EMP/MP20/Claudin tight junction UPF0182 PF03699.8 EGC37870.1 - 0.035 12.0 1.0 0.042 11.8 0.7 1.1 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0182) MARVEL PF01284.18 EGC37870.1 - 0.076 12.8 12.5 0.046 13.5 5.3 2.5 2 1 0 2 2 2 0 Membrane-associating domain DUF4231 PF14015.1 EGC37870.1 - 0.97 9.4 4.8 2.4 8.1 1.1 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4231) CbiQ PF02361.11 EGC37870.1 - 2.9 7.3 12.0 0.092 12.2 4.2 1.5 2 0 0 2 2 2 0 Cobalt transport protein O-antigen_lig PF13425.1 EGC37870.1 - 4.6 7.2 18.1 50 3.8 11.1 2.6 2 1 0 2 2 2 0 O-antigen ligase like membrane protein CD20 PF04103.10 EGC37871.1 - 0.00088 19.2 11.1 0.0057 16.5 1.1 2.9 1 1 1 2 2 2 1 CD20-like family DUF2776 PF10951.3 EGC37871.1 - 0.089 11.8 8.3 0.024 13.6 0.8 2.4 3 0 0 3 3 3 0 Protein of unknown function (DUF2776) Claudin_3 PF06653.6 EGC37871.1 - 0.16 11.7 16.4 0.64 9.7 9.9 2.6 2 1 0 2 2 2 0 Tight junction protein, Claudin-like DUF4131 PF13567.1 EGC37871.1 - 0.24 10.8 2.3 0.23 10.8 0.6 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) DUF4013 PF13197.1 EGC37871.1 - 0.28 10.5 13.9 0.077 12.3 4.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF4013) Mito_carr PF00153.22 EGC37872.1 - 1.5e-68 226.5 1.6 1.2e-21 76.2 0.0 3.1 3 0 0 3 3 3 3 Mitochondrial carrier protein UcrQ PF02939.11 EGC37872.1 - 0.095 12.5 0.0 6.2 6.7 0.0 3.0 3 0 0 3 3 3 0 UcrQ family PAS_3 PF08447.6 EGC37873.1 - 5e-15 55.3 0.0 1.1e-14 54.3 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS PF00989.19 EGC37873.1 - 1.2e-11 44.3 0.0 2.7e-08 33.5 0.0 2.5 2 0 0 2 2 2 2 PAS fold PAS_9 PF13426.1 EGC37873.1 - 6.2e-11 42.5 0.0 4.9e-09 36.4 0.0 2.9 3 1 0 3 3 3 1 PAS domain PAS_4 PF08448.5 EGC37873.1 - 2.4e-05 24.3 0.0 0.0027 17.7 0.0 2.4 2 0 0 2 2 2 1 PAS fold GAF_3 PF13492.1 EGC37873.1 - 0.00032 20.7 0.0 0.07 13.2 0.0 2.8 2 1 0 2 2 2 1 GAF domain PAS_8 PF13188.1 EGC37873.1 - 0.00073 19.3 0.0 0.87 9.5 0.0 2.6 2 0 0 2 2 2 2 PAS domain DUF1211 PF06736.6 EGC37873.1 - 0.019 15.0 0.0 0.053 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1211) Hist_deacetyl PF00850.14 EGC37874.1 - 1.2e-71 241.5 0.2 2.7e-71 240.4 0.1 1.6 1 0 0 1 1 1 1 Histone deacetylase domain AT_hook PF02178.14 EGC37874.1 - 0.16 11.6 2.3 8.3 6.4 0.4 3.0 2 0 0 2 2 2 0 AT hook motif DUF4419 PF14388.1 EGC37875.1 - 2.6e-95 319.0 1.3 2.6e-95 319.0 0.9 1.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4419) PUL PF08324.6 EGC37875.1 - 0.018 13.8 0.1 0.046 12.5 0.1 1.6 1 0 0 1 1 1 0 PUL domain Imm14 PF15428.1 EGC37875.1 - 0.029 14.7 2.1 0.19 12.1 0.8 2.6 3 0 0 3 3 3 0 Immunity protein 14 ECR1_N PF14382.1 EGC37877.1 - 1.4e-09 37.1 0.0 2.6e-09 36.1 0.0 1.5 1 0 0 1 1 1 1 Exosome complex exonuclease RRP4 N-terminal region HSP20 PF00011.16 EGC37877.1 - 0.074 12.9 0.1 15 5.5 0.1 2.6 2 0 0 2 2 2 0 Hsp20/alpha crystallin family DUF3936 PF13072.1 EGC37877.1 - 0.085 12.3 1.9 0.3 10.5 1.3 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3936) EXOSC1 PF10447.4 EGC37877.1 - 0.088 12.7 1.7 8.2 6.4 0.0 3.3 3 0 0 3 3 3 0 Exosome component EXOSC1/CSL4 ATP-synt_B PF00430.13 EGC37877.1 - 0.2 11.4 3.3 1.9 8.3 0.1 2.2 2 0 0 2 2 2 0 ATP synthase B/B' CF(0) EF-hand_7 PF13499.1 EGC37878.1 - 3e-07 30.4 0.2 3e-07 30.4 0.1 2.1 2 0 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC37878.1 - 8e-05 21.6 0.1 0.0034 16.5 0.1 2.8 3 0 0 3 3 3 1 EF hand EF-hand_6 PF13405.1 EGC37878.1 - 0.0022 17.7 0.5 0.02 14.7 0.2 2.5 1 1 0 2 2 2 1 EF-hand domain TPR_19 PF14559.1 EGC37878.1 - 0.013 15.8 0.2 0.044 14.1 0.1 2.0 1 1 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37878.1 - 0.014 15.2 0.2 0.46 10.4 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_11 PF13414.1 EGC37878.1 - 0.068 12.8 0.2 0.24 11.0 0.0 2.0 2 0 0 2 2 2 0 TPR repeat TPR_1 PF00515.23 EGC37878.1 - 0.2 11.3 2.9 0.58 9.8 0.1 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat ABC2_membrane_3 PF12698.2 EGC37880.1 - 1.6e-52 178.6 66.1 4.1e-30 105.0 22.4 2.2 2 0 0 2 2 2 2 ABC-2 family transporter protein ABC_tran PF00005.22 EGC37880.1 - 2.3e-51 173.6 0.1 3.6e-25 88.8 0.0 2.6 2 0 0 2 2 2 2 ABC transporter AAA_29 PF13555.1 EGC37880.1 - 8.2e-06 25.2 1.4 0.0024 17.3 0.0 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGC37880.1 - 2.8e-05 23.4 0.0 1.2 8.2 0.0 3.8 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain SRP54 PF00448.17 EGC37880.1 - 0.00098 18.6 2.0 0.45 9.9 0.1 2.4 2 0 0 2 2 2 2 SRP54-type protein, GTPase domain AAA_23 PF13476.1 EGC37880.1 - 0.0056 17.0 10.6 0.059 13.6 0.6 3.6 3 1 0 3 3 3 2 AAA domain AAA_25 PF13481.1 EGC37880.1 - 0.012 15.0 0.2 1.2 8.4 0.0 2.6 2 0 0 2 2 2 0 AAA domain ABC2_membrane_2 PF12679.2 EGC37880.1 - 0.017 13.9 41.5 0.022 13.6 14.1 2.8 3 0 0 3 3 3 0 ABC-2 family transporter protein SbcCD_C PF13558.1 EGC37880.1 - 0.021 14.7 0.0 1.4 8.9 0.0 3.3 2 2 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_33 PF13671.1 EGC37880.1 - 0.071 12.9 0.4 6.1 6.7 0.0 2.4 2 0 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC37880.1 - 0.089 11.9 0.5 1.5 8.0 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function, DUF258 ABC2_membrane PF01061.19 EGC37880.1 - 0.4 9.7 52.3 0.035 13.2 13.1 4.4 5 0 0 5 5 5 0 ABC-2 type transporter MAP PF03642.8 EGC37881.1 - 0.085 13.0 0.1 0.15 12.2 0.1 1.6 1 1 0 1 1 1 0 MAP domain EGF_2 PF07974.8 EGC37882.1 - 2.3e-05 24.4 12.0 4.6e-05 23.4 8.3 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EGC37882.1 - 0.0034 17.3 2.3 0.0068 16.4 1.6 1.5 1 0 0 1 1 1 1 Human growth factor-like EGF Dscam_C PF12355.3 EGC37882.1 - 0.045 14.0 0.5 0.15 12.3 0.3 1.9 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal EB PF01683.13 EGC37882.1 - 0.05 13.6 6.0 0.023 14.7 2.5 1.6 2 0 0 2 2 2 0 EB module EGF PF00008.22 EGC37882.1 - 0.067 13.1 5.8 0.12 12.3 4.0 1.5 1 0 0 1 1 1 0 EGF-like domain DUF3883 PF13020.1 EGC37882.1 - 0.22 11.2 1.3 19 5.0 0.0 2.7 3 0 0 3 3 3 0 Domain of unknown function (DUF3883) EGF_2 PF07974.8 EGC37883.1 - 2.9e-05 24.1 12.0 5.8e-05 23.1 8.3 1.5 1 0 0 1 1 1 1 EGF-like domain hEGF PF12661.2 EGC37883.1 - 0.0042 17.0 2.3 0.0087 16.0 1.6 1.6 1 0 0 1 1 1 1 Human growth factor-like EGF EB PF01683.13 EGC37883.1 - 0.017 15.1 4.3 0.047 13.7 3.0 1.7 1 0 0 1 1 1 0 EB module Dscam_C PF12355.3 EGC37883.1 - 0.068 13.4 0.5 0.2 11.9 0.3 1.7 1 0 0 1 1 1 0 Down syndrome cell adhesion molecule C terminal EGF PF00008.22 EGC37883.1 - 0.082 12.8 5.8 0.16 11.9 4.0 1.5 1 0 0 1 1 1 0 EGF-like domain SHMT PF00464.14 EGC37884.1 - 4.9e-183 608.0 0.0 5.7e-183 607.7 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_1_2 PF00155.16 EGC37884.1 - 1e-05 24.7 0.0 7.6e-05 21.8 0.0 2.3 2 1 0 2 2 2 1 Aminotransferase class I and II Aminotran_5 PF00266.14 EGC37884.1 - 5.3e-05 22.1 0.0 7.6e-05 21.6 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGC37884.1 - 0.01 14.9 0.0 0.025 13.7 0.0 1.6 1 1 0 1 1 1 0 Beta-eliminating lyase FERM_M PF00373.13 EGC37885.1 - 1.8e-48 163.8 1.4 3.9e-23 81.9 0.0 2.8 2 0 0 2 2 2 2 FERM central domain FERM_N PF09379.5 EGC37885.1 - 1.1e-28 99.1 5.6 6.3e-13 48.5 0.1 4.9 5 0 0 5 5 5 3 FERM N-terminal domain ACBP PF00887.14 EGC37885.1 - 5.2e-06 26.0 0.1 0.051 13.2 0.0 3.3 2 0 0 2 2 2 2 Acyl CoA binding protein IRS PF02174.12 EGC37885.1 - 3.9e-05 23.1 0.0 0.0013 18.3 0.0 2.7 2 0 0 2 2 2 1 PTB domain (IRS-1 type) RA PF00788.18 EGC37885.1 - 0.084 13.3 4.3 2.3 8.7 0.0 3.2 3 0 0 3 3 3 0 Ras association (RalGDS/AF-6) domain DUF3439 PF11921.3 EGC37885.1 - 1.9 8.2 10.0 5.6 6.7 7.0 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) ETC_C1_NDUFA5 PF04716.9 EGC37887.1 - 1.8e-18 65.8 0.5 3.4e-18 64.9 0.4 1.5 1 0 0 1 1 1 1 ETC complex I subunit conserved region Omega_Repress PF07764.6 EGC37887.1 - 0.046 14.0 0.2 0.069 13.5 0.1 1.4 1 0 0 1 1 1 0 Omega Transcriptional Repressor FATC PF02260.15 EGC37887.1 - 0.14 11.6 0.0 0.37 10.2 0.0 1.7 2 0 0 2 2 2 0 FATC domain DHO_dh PF01180.16 EGC37887.1 - 0.16 10.9 0.1 0.16 10.9 0.1 1.5 2 0 0 2 2 2 0 Dihydroorotate dehydrogenase LEAP-2 PF07359.6 EGC37888.1 - 7.2 6.3 21.3 1.2 8.8 0.3 4.7 1 1 3 4 4 4 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) FAR1 PF03101.10 EGC37890.1 - 0.0025 18.2 8.1 0.0025 18.2 5.6 4.1 4 2 0 4 4 4 1 FAR1 DNA-binding domain RAI1 PF08652.6 EGC37891.1 - 0.15 11.8 0.6 2.1 8.1 0.0 2.4 2 0 0 2 2 2 0 RAI1 like PD-(D/E)XK nuclease Homeobox PF00046.24 EGC37892.1 - 3e-10 39.5 0.2 3e-10 39.5 0.1 2.0 2 0 0 2 2 2 1 Homeobox domain fn3 PF00041.16 EGC37893.1 - 0.014 15.5 0.2 0.026 14.6 0.1 1.5 1 0 0 1 1 1 0 Fibronectin type III domain DUF208 PF02677.9 EGC37893.1 - 0.1 12.4 0.2 0.15 11.8 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized BCR, COG1636 FAST_2 PF08368.7 EGC37893.1 - 0.12 12.7 0.4 0.26 11.6 0.2 1.6 1 1 0 1 1 1 0 FAST kinase-like protein, subdomain 2 Pga1 PF10333.4 EGC37893.1 - 0.66 9.6 5.2 0.12 12.0 0.2 2.1 1 1 0 2 2 2 0 GPI-Mannosyltransferase II co-activator DUF4042 PF13251.1 EGC37894.1 - 1.1e-35 122.7 1.4 2.5e-15 56.4 0.4 4.6 5 0 0 5 5 5 3 Domain of unknown function (DUF4042) HEAT PF02985.17 EGC37894.1 - 1.4e-15 55.8 0.4 0.3 11.2 0.0 8.1 8 0 0 8 8 8 4 HEAT repeat HEAT_2 PF13646.1 EGC37894.1 - 1.2e-11 44.7 0.0 0.017 15.3 0.0 5.6 4 1 2 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EGC37894.1 - 3.2e-11 43.3 0.1 0.49 10.9 0.0 6.2 7 1 1 8 8 8 3 HEAT-like repeat Spore_YpjB PF09577.5 EGC37894.1 - 0.0099 15.4 0.1 0.031 13.8 0.0 1.8 1 0 0 1 1 1 1 Sporulation protein YpjB (SpoYpjB) Arm PF00514.18 EGC37894.1 - 0.029 14.2 9.6 12 5.8 0.4 5.9 5 2 2 7 7 7 0 Armadillo/beta-catenin-like repeat Arf PF00025.16 EGC37895.1 - 5.3e-63 211.3 0.0 6e-63 211.2 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family G-alpha PF00503.15 EGC37895.1 - 7.1e-11 41.4 0.1 3.8e-08 32.4 0.0 2.2 1 1 0 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGC37895.1 - 8.1e-09 34.9 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC37895.1 - 1.5e-08 34.2 0.0 1.6e-08 34.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC37895.1 - 9.2e-06 26.1 0.0 1.3e-05 25.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC37895.1 - 9.4e-05 22.3 0.0 0.00014 21.7 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGC37895.1 - 0.00035 19.7 0.0 0.00045 19.4 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC37895.1 - 0.031 13.6 0.0 1.1 8.6 0.0 2.0 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC37895.1 - 0.065 12.7 0.0 0.14 11.6 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Actin PF00022.14 EGC37896.1 - 3e-119 397.9 0.0 3.4e-119 397.7 0.0 1.0 1 0 0 1 1 1 1 Actin MreB_Mbl PF06723.8 EGC37896.1 - 0.00019 20.1 0.0 0.00033 19.3 0.0 1.3 1 0 0 1 1 1 1 MreB/Mbl protein DUF1702 PF08012.6 EGC37896.1 - 0.15 10.6 0.0 0.25 9.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1702) TRAPPC10 PF12584.3 EGC37898.1 - 1.3e-14 53.9 1.3 3e-14 52.7 0.0 2.3 3 0 0 3 3 3 1 Trafficking protein particle complex subunit 10, TRAPPC10 Foie-gras_1 PF11817.3 EGC37898.1 - 1.7e-12 47.3 0.1 7.1e-11 42.0 0.0 2.4 2 0 0 2 2 2 1 Foie gras liver health family 1 TPR_12 PF13424.1 EGC37898.1 - 0.02 14.8 1.1 0.34 10.8 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37898.1 - 0.06 12.9 3.2 0.1 12.2 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat SNAP PF14938.1 EGC37898.1 - 0.08 12.0 0.5 1.3 8.0 0.0 2.3 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP TPR_11 PF13414.1 EGC37898.1 - 0.083 12.5 0.3 0.83 9.3 0.0 2.3 2 0 0 2 2 2 0 TPR repeat TPR_16 PF13432.1 EGC37898.1 - 0.17 12.5 0.3 3.7 8.3 0.0 2.3 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC37898.1 - 0.75 9.8 3.1 0.76 9.8 0.1 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF3298 PF11738.3 EGC37898.1 - 3.8 8.0 6.3 3.7 8.1 0.1 3.7 4 0 0 4 4 4 0 Protein of unknown function (DUF3298) RE_Bsp6I PF09504.5 EGC37899.1 - 0.34 10.3 2.6 0.42 10.0 1.4 1.5 1 1 0 1 1 1 0 Bsp6I restriction endonuclease Sigma70_r3 PF04539.11 EGC37900.1 - 0.0036 17.1 0.0 0.73 9.7 0.0 2.4 2 0 0 2 2 2 2 Sigma-70 region 3 UPF0118 PF01594.11 EGC37900.1 - 0.02 13.9 0.3 0.03 13.3 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function DUF20 UPF0154 PF03672.8 EGC37900.1 - 0.052 13.1 0.5 15 5.3 0.0 3.3 3 0 0 3 3 3 0 Uncharacterised protein family (UPF0154) Death PF00531.17 EGC37900.1 - 0.066 12.9 0.1 32 4.3 0.0 3.3 2 1 1 3 3 3 0 Death domain TFIIE_alpha PF02002.12 EGC37900.1 - 0.23 10.9 2.1 0.37 10.3 0.1 2.0 2 0 0 2 2 2 0 TFIIE alpha subunit Arm PF00514.18 EGC37901.1 - 7.9e-61 199.9 18.0 4.9e-12 45.2 0.0 8.8 9 1 0 9 9 9 7 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC37901.1 - 1.1e-17 64.0 0.0 0.0003 20.9 0.0 6.0 1 1 5 6 6 6 4 HEAT repeats HEAT_EZ PF13513.1 EGC37901.1 - 1.2e-14 54.2 0.1 8.6e-06 26.0 0.0 5.2 4 2 1 5 5 5 3 HEAT-like repeat IBB PF01749.15 EGC37901.1 - 5.4e-11 42.5 4.8 1.1e-10 41.4 3.3 1.5 1 0 0 1 1 1 1 Importin beta binding domain HEAT PF02985.17 EGC37901.1 - 4.2e-09 35.7 0.3 0.047 13.7 0.0 6.4 7 0 0 7 7 7 2 HEAT repeat Arm_2 PF04826.8 EGC37901.1 - 0.00097 18.3 2.2 0.16 11.0 0.4 3.8 2 2 1 3 3 3 1 Armadillo-like Proteasom_PSMB PF10508.4 EGC37901.1 - 0.014 13.6 0.8 0.13 10.4 0.5 2.4 2 1 1 3 3 3 0 Proteasome non-ATPase 26S subunit DUF3361 PF11841.3 EGC37901.1 - 0.099 12.3 4.8 0.63 9.7 0.1 3.1 2 1 1 3 3 3 0 Domain of unknown function (DUF3361) SEN1_N PF12726.2 EGC37901.1 - 0.29 9.1 3.6 0.44 8.5 0.5 2.3 2 1 1 3 3 3 0 SEN1 N terminal YEATS PF03366.11 EGC37903.1 - 1.9e-24 85.1 0.5 5.3e-24 83.7 0.3 1.8 1 0 0 1 1 1 1 YEATS family MIP-T3 PF10243.4 EGC37903.1 - 2.2e-10 39.6 32.7 2.2e-10 39.6 22.7 4.3 3 1 0 3 3 3 1 Microtubule-binding protein MIP-T3 zf-ribbon_3 PF13248.1 EGC37903.1 - 1 8.6 2.6 9.4 5.5 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-Di19 PF05605.7 EGC37903.1 - 1.3 9.1 4.7 0.56 10.3 0.7 2.3 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding ABC_tran PF00005.22 EGC37905.1 - 4.3e-05 23.8 0.0 0.0002 21.6 0.0 2.1 1 0 0 1 1 1 1 ABC transporter AAA_22 PF13401.1 EGC37905.1 - 0.035 14.2 0.0 2 8.5 0.0 2.9 3 0 0 3 3 3 0 AAA domain SMC_N PF02463.14 EGC37905.1 - 0.13 11.4 6.2 0.038 13.2 0.6 2.7 2 1 0 2 2 2 0 RecF/RecN/SMC N terminal domain DUF948 PF06103.6 EGC37905.1 - 0.42 10.5 5.5 2 8.3 0.6 3.1 4 0 0 4 4 4 0 Bacterial protein of unknown function (DUF948) MtN3_slv PF03083.11 EGC37906.1 - 1.4e-21 76.1 23.0 1.3e-13 50.5 4.9 2.8 2 1 1 3 3 3 2 Sugar efflux transporter for intercellular exchange 2TM PF13239.1 EGC37906.1 - 0.012 15.6 0.7 0.012 15.6 0.5 2.5 1 1 1 2 2 2 0 2TM domain DUF4293 PF14126.1 EGC37906.1 - 0.25 11.2 9.4 0.085 12.7 2.5 2.3 1 1 0 2 2 2 0 Domain of unknown function (DUF4293) RRM_1 PF00076.17 EGC37907.1 - 3.9e-17 61.6 0.1 7.1e-17 60.8 0.1 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37907.1 - 7.6e-10 38.6 0.0 1.2e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37907.1 - 7.5e-09 35.3 0.1 2.5e-08 33.6 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC37907.1 - 0.0075 16.0 0.0 0.013 15.2 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif DUF2408 PF10303.4 EGC37908.1 - 0.0036 17.4 3.5 0.0037 17.3 2.4 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF2408) Cwf_Cwc_15 PF04889.7 EGC37908.1 - 0.036 13.7 9.3 0.036 13.7 6.4 1.2 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein NEMO PF11577.3 EGC37908.1 - 0.044 13.5 10.7 0.06 13.0 7.4 1.1 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Perilipin PF03036.11 EGC37908.1 - 0.053 12.3 3.2 0.054 12.3 2.2 1.0 1 0 0 1 1 1 0 Perilipin family Ax_dynein_light PF10211.4 EGC37908.1 - 0.079 12.7 12.0 0.089 12.6 8.3 1.1 1 0 0 1 1 1 0 Axonemal dynein light chain MRP-S31 PF15433.1 EGC37908.1 - 0.17 11.2 8.4 0.19 11.1 5.8 1.0 1 0 0 1 1 1 0 Mitochondrial 28S ribosomal protein S31 U1snRNP70_N PF12220.3 EGC37908.1 - 0.2 11.9 11.6 0.32 11.3 8.0 1.3 1 0 0 1 1 1 0 U1 small nuclear ribonucleoprotein of 70kDa MW N terminal Exonuc_VII_L PF02601.10 EGC37908.1 - 0.21 10.7 5.2 0.24 10.5 3.6 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit PRP1_N PF06424.7 EGC37908.1 - 0.38 11.0 7.1 0.46 10.7 4.9 1.2 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal Atrophin-1 PF03154.10 EGC37908.1 - 0.46 8.5 6.2 0.46 8.5 4.3 1.0 1 0 0 1 1 1 0 Atrophin-1 family DUF573 PF04504.9 EGC37908.1 - 0.52 10.6 8.8 0.74 10.1 6.1 1.3 1 0 0 1 1 1 0 Protein of unknown function, DUF573 Mo25 PF08569.6 EGC37908.1 - 0.6 9.0 7.0 0.66 8.9 4.9 1.0 1 0 0 1 1 1 0 Mo25-like DUF3987 PF13148.1 EGC37908.1 - 0.67 8.4 7.7 0.72 8.3 5.3 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Peptidase_S30 PF01577.11 EGC37908.1 - 0.71 9.2 8.5 0.85 8.9 5.9 1.1 1 0 0 1 1 1 0 Potyvirus P1 protease L_lactis_ph-MCP PF06673.6 EGC37908.1 - 0.71 8.5 4.0 0.72 8.5 2.8 1.0 1 0 0 1 1 1 0 Lactococcus lactis bacteriophage major capsid protein HAUS6_N PF14661.1 EGC37908.1 - 1 8.6 6.0 1.1 8.5 4.1 1.1 1 0 0 1 1 1 0 HAUS augmin-like complex subunit 6 N-terminus DUF2215 PF10225.4 EGC37908.1 - 1.1 8.6 4.8 1.3 8.4 3.3 1.0 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) ATP-synt_E PF05680.7 EGC37908.1 - 1.3 9.0 10.4 1.6 8.7 7.2 1.2 1 0 0 1 1 1 0 ATP synthase E chain Vfa1 PF08432.5 EGC37908.1 - 1.4 8.9 14.2 1.5 8.8 9.8 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF3899 PF13038.1 EGC37908.1 - 5 7.3 5.1 8.4 6.6 3.5 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3899) DUF4570 PF15134.1 EGC37908.1 - 5.6 6.8 11.2 7.9 6.3 7.8 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4570) Spc24 PF08286.6 EGC37908.1 - 7.7 6.2 10.3 11 5.6 7.1 1.3 1 1 0 1 1 1 0 Spc24 subunit of Ndc80 Apis_Csd PF11671.3 EGC37908.1 - 9.1 6.0 8.1 11 5.8 5.6 1.3 1 1 0 1 1 1 0 Complementary sex determiner protein DUF106 PF01956.11 EGC37908.1 - 9.9 5.6 7.5 10 5.6 5.2 1.1 1 0 0 1 1 1 0 Integral membrane protein DUF106 Metallophos PF00149.23 EGC37909.1 - 3.3e-45 153.9 0.1 4.3e-45 153.5 0.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC37909.1 - 0.0075 16.1 0.0 0.012 15.4 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain zf-RING_2 PF13639.1 EGC37911.1 - 8.6e-08 31.8 9.4 8.6e-08 31.8 6.5 2.4 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC37911.1 - 0.00014 21.8 11.2 0.00014 21.8 7.8 2.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC37911.1 - 0.00017 21.1 6.5 0.00017 21.1 4.5 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37911.1 - 0.00049 19.6 11.8 0.00049 19.6 8.2 3.1 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC37911.1 - 0.00081 19.4 9.9 0.00081 19.4 6.8 3.2 2 2 0 2 2 2 1 RING-H2 zinc finger zf-TRAF PF02176.13 EGC37911.1 - 0.00085 19.6 19.9 0.0038 17.5 3.3 4.0 3 1 1 4 4 4 2 TRAF-type zinc finger zf-RING_5 PF14634.1 EGC37911.1 - 0.0034 17.0 9.3 0.0034 17.0 6.5 3.6 3 2 0 3 3 3 1 zinc-RING finger domain U-box PF04564.10 EGC37911.1 - 0.051 13.5 0.0 0.16 11.9 0.0 1.9 1 0 0 1 1 1 0 U-box domain Acid_PPase PF12689.2 EGC37911.1 - 0.077 12.6 1.2 0.33 10.5 0.0 2.1 2 0 0 2 2 2 0 Acid Phosphatase zf-Apc11 PF12861.2 EGC37911.1 - 2.7 7.8 9.9 0.11 12.3 1.5 2.6 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger CLU PF13236.1 EGC37913.1 - 2.3e-47 161.2 2.7 3.1e-47 160.8 0.0 2.3 2 0 0 2 2 2 1 Clustered mitochondria TPR_17 PF13431.1 EGC37913.1 - 3.8e-13 48.5 0.5 0.011 15.8 0.0 4.1 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC37913.1 - 4.2e-12 45.5 0.3 4.7e-06 26.1 0.1 3.0 2 1 1 3 3 3 3 TPR repeat eIF3_p135 PF12807.2 EGC37913.1 - 5e-09 36.3 0.1 5e-09 36.3 0.0 3.7 4 0 0 4 4 4 1 Translation initiation factor eIF3 subunit 135 TPR_12 PF13424.1 EGC37913.1 - 7.5e-06 25.7 0.0 0.058 13.3 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37913.1 - 1e-05 24.8 1.4 0.13 11.8 0.0 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC37913.1 - 1.3e-05 24.6 3.3 0.067 13.1 0.0 4.0 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC37913.1 - 0.00016 21.9 0.0 0.16 12.6 0.0 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC37913.1 - 0.00087 19.5 0.0 0.15 12.3 0.0 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37913.1 - 0.0062 17.1 0.0 0.049 14.3 0.0 2.1 2 0 0 2 2 2 1 Tetratricopeptide repeat NUDIX PF00293.23 EGC37914.1 - 3.1e-13 49.5 0.0 7e-13 48.3 0.0 1.5 1 0 0 1 1 1 1 NUDIX domain DCP2 PF05026.8 EGC37914.1 - 3.4e-10 39.6 0.6 3.4e-10 39.6 0.4 3.2 3 0 0 3 3 3 1 Dcp2, box A domain PAT1 PF09770.4 EGC37914.1 - 2.2 6.3 83.2 3 5.9 57.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 DUF605 PF04652.11 EGC37914.1 - 6.5 6.0 49.1 9.9 5.4 34.1 1.3 1 0 0 1 1 1 0 Vta1 like Metallophos PF00149.23 EGC37915.1 - 1.1e-43 148.9 0.1 1.5e-43 148.5 0.1 1.2 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase zf-Di19 PF05605.7 EGC37916.1 - 1.5e-11 44.2 11.9 7.9e-11 41.9 6.7 2.5 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-RING_2 PF13639.1 EGC37916.1 - 1.5e-10 40.6 5.7 1.5e-10 40.6 4.0 4.2 3 1 1 4 4 4 2 Ring finger domain SPRY PF00622.23 EGC37916.1 - 2.5e-05 24.3 0.5 9.1e-05 22.5 0.3 2.0 1 1 0 1 1 1 1 SPRY domain zf-rbx1 PF12678.2 EGC37916.1 - 5.1e-05 23.2 1.8 5.1e-05 23.2 1.3 3.5 2 1 0 2 2 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC37916.1 - 5.1e-05 22.8 16.0 0.043 13.4 2.1 4.2 4 0 0 4 4 4 2 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC37916.1 - 0.00017 21.5 5.8 0.00017 21.5 4.0 4.0 4 0 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Rad50_zn_hook PF04423.9 EGC37916.1 - 0.091 12.2 8.3 5.4 6.5 0.1 4.3 4 0 0 4 4 4 0 Rad50 zinc hook motif zf-C2H2_4 PF13894.1 EGC37916.1 - 0.28 11.6 11.2 12 6.4 0.3 3.9 3 0 0 3 3 3 0 C2H2-type zinc finger zf-TFIIB PF13453.1 EGC37916.1 - 0.34 10.1 6.9 1.1 8.5 2.0 2.6 2 0 0 2 2 2 0 Transcription factor zinc-finger Mucin PF01456.12 EGC37916.1 - 0.49 10.1 14.4 1.3 8.8 10.0 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein UPF0547 PF10571.4 EGC37916.1 - 0.75 9.5 8.8 0.87 9.3 0.1 3.7 4 1 0 4 4 4 0 Uncharacterised protein family UPF0547 zf-RING_5 PF14634.1 EGC37916.1 - 1.8 8.3 22.4 0.47 10.2 3.8 4.3 4 0 0 4 4 4 0 zinc-RING finger domain Paramyxo_C PF01692.13 EGC37916.1 - 2.1 7.9 6.0 3.7 7.0 4.1 1.3 1 0 0 1 1 1 0 Paramyxovirus non-structural protein c zf-C3HC4 PF00097.20 EGC37916.1 - 2.3 7.9 24.4 0.032 13.8 4.0 4.2 4 0 0 4 4 4 0 Zinc finger, C3HC4 type (RING finger) zf-ribbon_3 PF13248.1 EGC37916.1 - 3.1 7.1 7.3 16 4.8 1.5 2.8 2 0 0 2 2 2 0 zinc-ribbon domain Prok-RING_1 PF14446.1 EGC37916.1 - 8.9 6.1 16.7 21 4.9 2.4 4.1 4 0 0 4 4 4 0 Prokaryotic RING finger family 1 ATP-synt_10 PF05176.9 EGC37917.1 - 7.7e-20 71.2 1.1 9.1e-20 70.9 0.7 1.1 1 0 0 1 1 1 1 ATP10 protein DUF2718 PF10918.3 EGC37917.1 - 0.22 11.5 3.7 0.42 10.6 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2718) FNIP PF05725.7 EGC37918.1 - 4.4e-57 189.8 21.2 1.7e-15 56.6 0.2 5.1 4 1 1 5 5 5 5 FNIP Repeat DUF1769 PF08588.5 EGC37918.1 - 9.1e-05 22.3 5.3 0.98 9.4 0.2 4.9 3 3 2 5 5 5 2 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC37918.1 - 0.26 11.0 4.5 0.89 9.2 1.8 2.2 1 1 1 2 2 2 0 Leucine rich repeats (6 copies) Skp1 PF01466.14 EGC37919.1 - 1.2e-39 134.2 0.5 2.6e-39 133.1 0.1 1.7 2 0 0 2 2 2 1 Skp1 family, dimerisation domain Skp1_POZ PF03931.10 EGC37919.1 - 1.3e-27 95.6 3.1 1.6e-27 95.3 1.3 1.8 2 0 0 2 2 2 1 Skp1 family, tetramerisation domain Myb_DNA-binding PF00249.26 EGC37919.1 - 0.2 11.7 1.7 8.7 6.4 0.1 2.5 2 1 0 2 2 2 0 Myb-like DNA-binding domain Glyco_hydro_cc PF11790.3 EGC37921.1 - 1e-49 169.1 1.7 1.3e-49 168.7 1.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolase catalytic core DAO PF01266.19 EGC37922.1 - 1.2e-28 100.1 0.0 6.3e-28 97.7 0.0 1.8 1 1 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGC37922.1 - 0.044 12.8 0.0 0.078 12.0 0.0 1.4 1 0 0 1 1 1 0 FAD binding domain CBM49 PF09478.5 EGC37923.1 - 2e-12 47.0 1.8 3.1e-12 46.3 1.2 1.3 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Exo5 PF09810.4 EGC37924.1 - 0.006 15.8 0.9 0.0085 15.3 0.7 1.2 1 0 0 1 1 1 1 Exonuclease V - a 5' deoxyribonuclease NDK PF00334.14 EGC37925.1 - 1.3e-53 180.3 0.0 1.5e-53 180.2 0.0 1.0 1 0 0 1 1 1 1 Nucleoside diphosphate kinase DUF3414 PF11894.3 EGC37926.1 - 2.9e-51 173.7 66.1 2e-43 147.7 35.4 3.7 2 1 0 2 2 2 2 Protein of unknown function (DUF3414) G-alpha PF00503.15 EGC37928.1 - 1.5e-24 86.4 1.6 1.6e-24 86.3 1.1 1.0 1 0 0 1 1 1 1 G-protein alpha subunit EF1_GNE PF00736.14 EGC37929.1 - 2.6e-30 103.9 1.4 6e-30 102.7 1.0 1.7 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain PARP PF00644.15 EGC37929.1 - 5.5e-14 52.0 0.3 3.3e-13 49.5 0.0 2.2 1 1 1 2 2 2 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 EGC37929.1 - 1.1e-10 40.7 2.9 0.0001 21.6 0.3 2.6 1 1 1 2 2 2 2 WWE domain zf-CCHH PF10283.4 EGC37929.1 - 2.7e-09 36.7 2.4 2.7e-09 36.7 1.7 1.8 2 0 0 2 2 2 1 Zinc-finger (CX5CX6HX5H) motif BRCT PF00533.21 EGC37929.1 - 5.7e-08 32.8 0.3 4.3e-07 29.9 0.1 2.6 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC37929.1 - 7.6e-08 32.0 0.2 1.7e-07 30.9 0.2 1.6 1 0 0 1 1 1 1 twin BRCT domain EF-1_beta_acid PF10587.4 EGC37929.1 - 1.7e-05 24.8 7.2 1.7e-05 24.8 5.0 2.8 2 0 0 2 2 1 1 Eukaryotic elongation factor 1 beta central acidic region PAT1 PF09770.4 EGC37929.1 - 0.0017 16.6 19.7 0.0017 16.6 13.6 1.8 2 0 0 2 2 2 1 Topoisomerase II-associated protein PAT1 GST_C_3 PF14497.1 EGC37929.1 - 0.005 17.3 0.0 0.012 16.1 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C PF00043.20 EGC37929.1 - 0.081 12.9 0.0 0.27 11.2 0.0 1.9 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain Nucleoplasmin PF03066.10 EGC37929.1 - 0.79 9.2 7.3 0.36 10.3 0.3 2.5 2 0 0 2 2 2 0 Nucleoplasmin DUF3439 PF11921.3 EGC37929.1 - 2.1 8.0 10.7 6.6 6.5 7.5 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC37929.1 - 2.4 7.9 23.0 7.1 6.3 16.0 1.8 1 0 0 1 1 1 0 Mucin-like glycoprotein PTCB-BRCT PF12738.2 EGC37930.1 - 7.8e-06 25.6 0.1 2.2e-05 24.2 0.0 1.8 1 0 0 1 1 1 1 twin BRCT domain BRCT PF00533.21 EGC37930.1 - 0.00066 19.7 1.7 0.00066 19.7 1.2 3.3 2 2 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain Voldacs PF03517.8 EGC37932.1 - 1.2e-28 99.6 2.9 1.5e-28 99.3 2.0 1.2 1 0 0 1 1 1 1 Regulator of volume decrease after cellular swelling Vps36_ESCRT-II PF11605.3 EGC37932.1 - 0.0013 18.5 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Vacuolar protein sorting protein 36 Vps36 Myb_DNA-binding PF00249.26 EGC37933.1 - 0.00016 21.6 0.1 0.051 13.6 0.0 2.6 2 0 0 2 2 2 2 Myb-like DNA-binding domain PDEase_I PF00233.14 EGC37934.1 - 3.9e-69 232.9 6.5 8e-69 231.9 4.5 1.5 1 0 0 1 1 1 1 3'5'-cyclic nucleotide phosphodiesterase Response_reg PF00072.19 EGC37934.1 - 5.3e-27 94.0 0.2 1.2e-26 92.8 0.1 1.7 1 0 0 1 1 1 1 Response regulator receiver domain FleQ PF06490.6 EGC37934.1 - 0.013 15.6 0.0 0.17 12.0 0.0 2.8 2 0 0 2 2 2 0 Flagellar regulatory protein FleQ FliG_N PF14842.1 EGC37934.1 - 0.016 15.3 8.1 0.27 11.3 1.1 4.2 4 1 1 5 5 5 0 FliG N-terminal domain HD PF01966.17 EGC37934.1 - 0.086 12.8 0.6 0.28 11.2 0.0 2.2 2 0 0 2 2 2 0 HD domain Methyltransf_5 PF01795.14 EGC37935.1 - 7.1e-84 281.7 0.0 8.7e-84 281.4 0.0 1.1 1 0 0 1 1 1 1 MraW methylase family Arf PF00025.16 EGC37936.1 - 6.4e-67 224.1 0.0 7.4e-67 223.9 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC37936.1 - 5.8e-13 48.4 0.0 6.9e-13 48.2 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC37936.1 - 4.6e-10 38.7 1.0 1.1e-07 30.9 0.0 2.2 2 0 0 2 2 2 2 G-protein alpha subunit Ras PF00071.17 EGC37936.1 - 1.3e-09 37.6 0.0 1.7e-09 37.3 0.0 1.2 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC37936.1 - 1e-07 31.3 0.0 1.2e-07 31.0 0.0 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC37936.1 - 1.2e-07 32.2 0.0 1.7e-07 31.7 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein MMR_HSR1 PF01926.18 EGC37936.1 - 5.9e-07 29.4 0.0 7.8e-07 29.0 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase TRAPPC-Trs85 PF12739.2 EGC37936.1 - 0.018 13.6 0.0 0.02 13.5 0.0 1.1 1 0 0 1 1 1 0 ER-Golgi trafficking TRAPP I complex 85 kDa subunit 6PF2K PF01591.13 EGC37936.1 - 0.083 11.9 0.2 0.29 10.1 0.1 1.8 1 1 0 1 1 1 0 6-phosphofructo-2-kinase AAA_33 PF13671.1 EGC37936.1 - 0.084 12.7 1.1 1.4 8.8 0.0 2.3 2 1 1 3 3 3 0 AAA domain TIR_2 PF13676.1 EGC37936.1 - 0.096 12.8 0.0 0.15 12.2 0.0 1.3 1 0 0 1 1 1 0 TIR domain Tup_N PF08581.5 EGC37937.1 - 0.0064 16.6 0.8 0.02 15.0 0.5 1.8 1 0 0 1 1 1 1 Tup N-terminal TPR_11 PF13414.1 EGC37939.1 - 1.5e-09 37.3 4.9 4.3e-06 26.2 0.2 2.3 1 1 1 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC37939.1 - 5.9e-09 35.1 1.2 0.00085 19.0 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC37939.1 - 7.1e-08 31.7 6.8 0.0001 21.7 0.0 3.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC37939.1 - 0.00019 20.9 5.4 0.031 14.0 0.0 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC37939.1 - 0.0032 17.2 0.1 0.014 15.2 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC37939.1 - 0.0037 17.1 1.5 0.48 10.3 0.1 2.8 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC37939.1 - 0.0067 17.0 0.2 0.25 12.0 0.0 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat PPTA PF01239.17 EGC37939.1 - 0.0075 15.5 0.2 7.9 6.0 0.0 3.5 3 0 0 3 3 3 1 Protein prenyltransferase alpha subunit repeat TPR_17 PF13431.1 EGC37939.1 - 0.015 15.4 0.4 6.6 7.2 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC37939.1 - 0.022 14.6 0.8 2.2 8.1 0.0 3.0 2 1 1 3 3 3 0 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EGC37939.1 - 0.025 14.9 0.6 0.75 10.1 0.1 2.6 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC37939.1 - 0.08 13.6 0.7 0.55 11.0 0.1 2.4 2 1 1 3 3 3 0 Tetratricopeptide repeat MIT PF04212.13 EGC37939.1 - 0.11 12.4 2.4 0.33 10.8 0.1 2.6 3 0 0 3 3 3 0 MIT (microtubule interacting and transport) domain ABC_membrane PF00664.18 EGC37940.1 - 6.9e-64 215.9 51.2 1.8e-34 119.4 13.0 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC37940.1 - 1.8e-48 164.3 0.2 3.7e-29 101.7 0.1 2.7 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EGC37940.1 - 0.00026 20.2 0.2 0.13 11.4 0.0 2.3 2 0 0 2 2 2 2 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGC37940.1 - 0.0057 16.6 0.4 2.1 8.3 0.1 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase T2SE PF00437.15 EGC37940.1 - 0.012 14.5 0.2 0.8 8.5 0.0 2.3 2 0 0 2 2 2 0 Type II/IV secretion system protein AAA_22 PF13401.1 EGC37940.1 - 0.017 15.2 1.0 3.2 7.9 0.0 3.2 2 1 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGC37940.1 - 0.025 14.1 0.7 2 7.9 0.2 2.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain Miro PF08477.8 EGC37940.1 - 0.056 13.9 0.8 17 5.9 0.0 2.8 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EGC37940.1 - 0.073 13.2 0.8 2.8 8.1 0.0 3.0 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGC37940.1 - 0.092 12.1 0.0 4.4 6.6 0.0 2.3 2 0 0 2 2 2 0 AAA domain ArgK PF03308.11 EGC37940.1 - 0.1 11.3 0.4 3.6 6.2 0.0 2.9 3 0 0 3 3 3 0 ArgK protein FtsK_SpoIIIE PF01580.13 EGC37940.1 - 0.21 11.0 0.1 8.3 5.8 0.0 2.2 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA_17 PF13207.1 EGC37940.1 - 0.46 11.2 4.6 2.6 8.9 0.4 3.4 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGC37940.1 - 6.5 7.0 8.5 1.3 9.3 0.0 3.3 4 0 0 4 4 2 0 AAA domain DUF2362 PF10154.4 EGC37941.1 - 5.9e-94 315.5 61.2 1.6e-50 172.3 0.2 4.1 1 1 3 4 4 4 4 Uncharacterized conserved protein (DUF2362) Myb_DNA-binding PF00249.26 EGC37942.1 - 0.017 15.1 0.0 0.035 14.1 0.0 1.5 1 0 0 1 1 1 0 Myb-like DNA-binding domain Pkinase_Tyr PF07714.12 EGC37943.1 - 1.3e-68 230.8 0.0 1.9e-68 230.3 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase SPRY PF00622.23 EGC37943.1 - 8.7e-60 200.2 11.2 6.8e-21 74.6 0.2 3.5 3 0 0 3 3 3 3 SPRY domain Pkinase PF00069.20 EGC37943.1 - 8.1e-54 182.4 0.0 1.3e-53 181.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain SAM_2 PF07647.12 EGC37943.1 - 3.5e-16 58.7 0.1 7.2e-16 57.7 0.1 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_1 PF00536.25 EGC37943.1 - 5.3e-14 52.1 0.0 1.1e-13 51.1 0.0 1.6 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) DUF4044 PF13253.1 EGC37944.1 - 0.078 12.1 0.4 0.13 11.4 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) Bacteriocin_IIc PF10439.4 EGC37944.1 - 0.53 10.4 7.1 0.91 9.6 4.9 1.6 1 1 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Coiled PF05710.7 EGC37944.1 - 7.2 7.1 10.1 12 6.4 7.0 1.5 1 1 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC37945.1 - 0.003 17.9 3.2 0.0037 17.7 2.2 1.1 1 0 0 1 1 1 1 Coiled coil Gly-zipper_OmpA PF13436.1 EGC37945.1 - 3.6 7.2 10.5 4.6 6.9 7.3 1.3 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Gly-zipper_YMGG PF13441.1 EGC37945.1 - 9.6 5.8 15.3 5.5 6.5 9.2 1.7 1 1 0 1 1 1 0 YMGG-like Gly-zipper Gly-zipper_OmpA PF13436.1 EGC37946.1 - 0.41 10.3 7.3 0.6 9.7 5.1 1.3 1 1 0 1 1 1 0 Glycine-zipper containing OmpA-like membrane domain Coiled PF05710.7 EGC37946.1 - 0.41 11.1 6.9 0.5 10.8 4.8 1.1 1 0 0 1 1 1 0 Coiled coil Mito_fiss_reg PF05308.6 EGC37947.1 - 1.7 7.9 17.5 0.019 14.3 5.7 2.3 2 0 0 2 2 2 0 Mitochondrial fission regulator FMN_dh PF01070.13 EGC37948.1 - 1.5e-134 448.3 0.0 2e-134 447.9 0.0 1.1 1 0 0 1 1 1 1 FMN-dependent dehydrogenase NMO PF03060.10 EGC37948.1 - 3e-09 36.4 0.2 5.2e-09 35.7 0.1 1.4 1 0 0 1 1 1 1 Nitronate monooxygenase ThiG PF05690.9 EGC37948.1 - 1.4e-07 30.8 0.1 0.0016 17.5 0.0 2.3 2 0 0 2 2 2 2 Thiazole biosynthesis protein ThiG IMPDH PF00478.20 EGC37948.1 - 6.2e-07 28.6 3.0 4.4e-06 25.8 0.1 3.0 3 1 0 4 4 4 1 IMP dehydrogenase / GMP reductase domain PA PF02225.17 EGC37948.1 - 1.2e-05 24.8 0.1 3.1 7.5 0.0 3.3 2 1 1 3 3 3 3 PA domain Glu_synthase PF01645.12 EGC37948.1 - 3.1e-05 23.0 0.1 6.6e-05 21.9 0.0 1.5 2 0 0 2 2 2 1 Conserved region in glutamate synthase His_biosynth PF00977.16 EGC37948.1 - 5e-05 22.6 0.2 0.0026 17.0 0.0 2.8 2 1 1 3 3 3 1 Histidine biosynthesis protein DHO_dh PF01180.16 EGC37948.1 - 6.4e-05 22.0 0.2 0.00038 19.5 0.1 2.4 1 1 1 2 2 2 1 Dihydroorotate dehydrogenase TMP-TENI PF02581.12 EGC37948.1 - 0.0015 17.6 0.1 0.028 13.5 0.0 2.5 2 0 0 2 2 2 1 Thiamine monophosphate synthase/TENI PcrB PF01884.12 EGC37948.1 - 0.0041 16.4 0.5 0.69 9.1 0.1 2.7 1 1 0 2 2 2 1 PcrB family IGPS PF00218.16 EGC37948.1 - 0.055 12.5 0.0 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Indole-3-glycerol phosphate synthase FlpD PF02662.11 EGC37948.1 - 0.1 12.2 0.0 1.3 8.7 0.0 2.4 2 0 0 2 2 2 0 Methyl-viologen-reducing hydrogenase, delta subunit p450 PF00067.17 EGC37949.1 - 1.7e-81 274.1 0.2 2.5e-81 273.5 0.2 1.2 1 1 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGC37950.1 - 1.7e-74 251.0 2.2 2.1e-74 250.7 1.5 1.1 1 0 0 1 1 1 1 Cytochrome P450 Plasmod_dom_1 PF09715.5 EGC37950.1 - 0.29 11.1 7.8 0.086 12.7 1.4 2.9 2 1 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) p450 PF00067.17 EGC37951.1 - 0.0011 17.5 0.1 0.0013 17.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGC37952.1 - 3.2e-64 217.1 3.0 3.6e-64 216.9 2.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Gpi16 PF04113.9 EGC37953.1 - 1.5e-132 442.5 5.1 3.8e-129 431.2 3.5 3.1 1 1 0 1 1 1 1 Gpi16 subunit, GPI transamidase component Senescence_reg PF04520.8 EGC37954.1 - 0.72 10.3 4.2 1.7 9.1 2.9 1.6 1 0 0 1 1 1 0 Senescence regulator Pkinase PF00069.20 EGC37955.1 - 3.6e-56 190.1 0.0 5e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37955.1 - 1.1e-33 116.4 0.0 1.5e-33 115.9 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC37955.1 - 1e-06 27.9 0.0 1.6e-06 27.3 0.0 1.3 1 0 0 1 1 1 1 Kinase-like Cse1 PF08506.5 EGC37956.1 - 4.3e-112 374.3 7.2 9.6e-112 373.1 5.0 1.6 1 0 0 1 1 1 1 Cse1 CAS_CSE1 PF03378.10 EGC37956.1 - 1.2e-92 310.4 7.7 1.2e-92 310.4 5.4 2.4 3 0 0 3 3 3 1 CAS/CSE protein, C-terminus IBN_N PF03810.14 EGC37956.1 - 2.1e-11 43.5 0.3 6.3e-10 38.8 0.0 3.2 3 0 0 3 3 3 1 Importin-beta N-terminal domain Xpo1 PF08389.7 EGC37956.1 - 0.0012 18.7 0.4 0.0012 18.7 0.3 4.8 4 2 1 5 5 5 1 Exportin 1-like protein UME PF08064.8 EGC37956.1 - 0.04 13.8 9.2 2.9 7.8 0.1 5.8 7 1 1 8 8 8 0 UME (NUC010) domain RIX1 PF08167.7 EGC37956.1 - 0.67 9.6 13.5 0.27 10.9 0.8 5.3 6 1 0 6 6 6 0 rRNA processing/ribosome biogenesis Glyco_transf_22 PF03901.12 EGC37957.1 - 5.2e-102 341.9 34.5 7.7e-102 341.4 23.9 1.2 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family BcrAD_BadFG PF01869.15 EGC37958.1 - 1.1e-39 136.4 0.0 1.2e-39 136.2 0.0 1.0 1 0 0 1 1 1 1 BadF/BadG/BcrA/BcrD ATPase family N2227 PF07942.7 EGC37958.1 - 0.071 12.0 0.0 6.1 5.7 0.0 2.3 3 0 0 3 3 3 0 N2227-like protein Beach PF02138.13 EGC37959.1 - 1.1e-101 339.8 3.3 2.2e-101 338.8 2.3 1.5 1 0 0 1 1 1 1 Beige/BEACH domain WD40 PF00400.27 EGC37959.1 - 2.8e-27 93.5 20.6 1.4e-07 31.1 1.9 6.8 7 0 0 7 7 7 5 WD domain, G-beta repeat PH_BEACH PF14844.1 EGC37959.1 - 1.6e-21 76.1 0.1 2.5e-19 69.0 0.0 2.9 2 1 0 2 2 2 1 PH domain associated with Beige/BEACH BBS2_Mid PF14783.1 EGC37959.1 - 0.0018 18.0 1.3 0.052 13.3 0.0 3.5 4 0 0 4 4 4 1 Ciliary BBSome complex subunit 2, middle region GRAM PF02893.15 EGC37959.1 - 0.0032 16.9 0.1 0.31 10.5 0.0 2.8 2 0 0 2 2 2 1 GRAM domain ERG4_ERG24 PF01222.12 EGC37960.1 - 2.2e-125 418.6 26.7 2.6e-125 418.3 18.5 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family Period_C PF12114.3 EGC37960.1 - 0.32 10.5 0.5 0.45 10.1 0.3 1.1 1 0 0 1 1 1 0 Period protein 2/3C-terminal region DUF2207 PF09972.4 EGC37960.1 - 1.2 7.6 6.7 3.8 5.9 0.0 2.4 2 1 0 2 2 2 0 Predicted membrane protein (DUF2207) AAA PF00004.24 EGC37961.1 - 7.3e-40 136.2 0.0 1.7e-39 135.0 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) Vps4_C PF09336.5 EGC37961.1 - 1.6e-28 98.3 0.0 6.3e-27 93.2 0.0 3.0 3 0 0 3 3 3 1 Vps4 C terminal oligomerisation domain MIT PF04212.13 EGC37961.1 - 8e-19 67.2 10.3 1.7e-18 66.2 5.5 2.5 2 0 0 2 2 2 1 MIT (microtubule interacting and transport) domain AAA_22 PF13401.1 EGC37961.1 - 2.4e-06 27.6 0.4 0.021 14.9 0.0 2.7 1 1 1 2 2 2 2 AAA domain RuvB_N PF05496.7 EGC37961.1 - 6.8e-06 25.2 0.0 1.7e-05 24.0 0.0 1.6 2 0 0 2 2 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGC37961.1 - 2e-05 25.3 0.0 8.8e-05 23.3 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_14 PF13173.1 EGC37961.1 - 2.5e-05 24.1 0.1 8.4e-05 22.4 0.0 1.8 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGC37961.1 - 6.3e-05 22.0 0.0 0.00012 21.0 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF815) TIP49 PF06068.8 EGC37961.1 - 6.5e-05 21.8 0.0 0.00011 21.0 0.0 1.3 1 0 0 1 1 1 1 TIP49 C-terminus AAA_5 PF07728.9 EGC37961.1 - 6.8e-05 22.6 0.0 0.00018 21.2 0.0 1.9 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_16 PF13191.1 EGC37961.1 - 0.00015 21.7 0.4 0.0017 18.3 0.0 2.3 2 1 1 3 3 3 1 AAA ATPase domain IstB_IS21 PF01695.12 EGC37961.1 - 0.00018 21.0 0.0 0.0005 19.5 0.0 1.8 2 0 0 2 2 2 1 IstB-like ATP binding protein AAA_25 PF13481.1 EGC37961.1 - 0.00018 20.9 0.3 0.045 13.1 0.0 2.4 1 1 1 2 2 2 1 AAA domain AAA_2 PF07724.9 EGC37961.1 - 0.00019 21.4 0.3 0.0018 18.2 0.0 2.2 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGC37961.1 - 0.00028 21.0 0.0 0.00098 19.2 0.0 2.0 1 0 0 1 1 1 1 RNA helicase AAA_18 PF13238.1 EGC37961.1 - 0.00097 19.4 1.2 0.0021 18.3 0.0 2.2 2 1 0 2 2 2 1 AAA domain KaiC PF06745.8 EGC37961.1 - 0.0012 17.9 0.4 0.21 10.6 0.1 2.4 1 1 1 2 2 2 1 KaiC AAA_33 PF13671.1 EGC37961.1 - 0.0016 18.2 0.4 0.011 15.6 0.0 2.3 2 1 0 2 2 2 1 AAA domain NACHT PF05729.7 EGC37961.1 - 0.0032 17.1 0.0 0.43 10.2 0.0 2.3 1 1 1 2 2 2 1 NACHT domain Zeta_toxin PF06414.7 EGC37961.1 - 0.0033 16.5 0.1 0.079 12.0 0.0 2.4 1 1 1 2 2 2 1 Zeta toxin AAA_24 PF13479.1 EGC37961.1 - 0.0079 15.8 6.6 0.044 13.3 0.2 2.6 2 1 0 2 2 2 1 AAA domain Zot PF05707.7 EGC37961.1 - 0.014 14.8 0.6 0.68 9.3 0.0 2.6 1 1 1 2 2 2 0 Zonular occludens toxin (Zot) Mg_chelatase PF01078.16 EGC37961.1 - 0.022 13.9 0.0 0.049 12.7 0.0 1.5 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI Viral_helicase1 PF01443.13 EGC37961.1 - 0.029 13.8 0.1 0.073 12.5 0.0 1.7 2 0 0 2 2 2 0 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EGC37961.1 - 0.032 13.9 0.0 0.081 12.6 0.0 1.6 1 0 0 1 1 1 0 Part of AAA domain PPV_E1_C PF00519.12 EGC37961.1 - 0.034 12.7 0.4 0.092 11.3 0.0 1.7 2 0 0 2 2 2 0 Papillomavirus helicase Arch_ATPase PF01637.13 EGC37961.1 - 0.039 13.6 6.1 0.54 9.9 0.0 3.0 2 1 1 3 3 3 0 Archaeal ATPase Torsin PF06309.6 EGC37961.1 - 0.04 13.8 0.0 0.13 12.1 0.0 1.8 2 0 0 2 2 1 0 Torsin ResIII PF04851.10 EGC37961.1 - 0.04 13.7 3.2 0.17 11.7 0.0 2.3 2 0 0 2 2 2 0 Type III restriction enzyme, res subunit PhoH PF02562.11 EGC37961.1 - 0.04 13.1 0.1 0.13 11.4 0.0 1.8 2 0 0 2 2 2 0 PhoH-like protein NB-ARC PF00931.17 EGC37961.1 - 0.043 12.6 0.0 0.087 11.6 0.0 1.4 1 0 0 1 1 1 0 NB-ARC domain Parvo_NS1 PF01057.12 EGC37961.1 - 0.048 12.5 0.9 0.075 11.8 0.0 1.7 2 0 0 2 2 2 0 Parvovirus non-structural protein NS1 Sigma54_activ_2 PF14532.1 EGC37961.1 - 0.069 13.1 0.0 0.25 11.3 0.0 1.9 2 0 0 2 2 1 0 Sigma-54 interaction domain ABC_tran PF00005.22 EGC37961.1 - 0.1 12.8 0.4 0.74 10.1 0.0 2.2 2 0 0 2 2 2 0 ABC transporter AAA_21 PF13304.1 EGC37961.1 - 0.26 11.1 2.0 2.3 8.1 0.0 2.7 2 1 1 3 3 3 0 AAA domain p450 PF00067.17 EGC37962.1 - 2e-46 158.4 0.0 1.4e-40 139.2 0.1 2.2 2 0 0 2 2 2 2 Cytochrome P450 DUF1084 PF06454.6 EGC37963.1 - 4.7e-15 55.3 18.7 6.1e-15 54.9 13.0 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) L6_membrane PF05805.7 EGC37963.1 - 0.031 13.8 0.2 0.031 13.8 0.1 2.2 3 0 0 3 3 3 0 L6 membrane protein BatA PF07584.6 EGC37963.1 - 3 8.1 0.0 3 8.1 0.0 3.7 5 1 0 5 5 5 0 Aerotolerance regulator N-terminal TMEM154 PF15102.1 EGC37964.1 - 0.0039 16.9 1.1 0.0074 16.0 0.8 1.5 1 0 0 1 1 1 1 TMEM154 protein family TIG PF01833.19 EGC37964.1 - 0.012 15.5 1.7 3.8 7.5 0.1 2.6 1 1 0 2 2 2 0 IPT/TIG domain ABC2_membrane_3 PF12698.2 EGC37964.1 - 0.51 9.3 9.4 1.7 7.6 6.5 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein TMEM156 PF15106.1 EGC37964.1 - 3.1 6.9 10.5 6.1 6.0 5.1 2.6 1 1 1 2 2 2 0 TMEM156 protein family PARP PF00644.15 EGC37965.1 - 3.5e-66 222.5 0.9 5.8e-66 221.8 0.6 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase catalytic domain PARP_reg PF02877.9 EGC37965.1 - 4.3e-27 94.3 1.7 7.2e-27 93.6 1.2 1.4 1 0 0 1 1 1 1 Poly(ADP-ribose) polymerase, regulatory domain WGR PF05406.10 EGC37965.1 - 1.9e-16 59.8 0.5 4e-16 58.7 0.4 1.6 1 0 0 1 1 1 1 WGR domain Ank_2 PF12796.2 EGC37966.1 - 5.6e-31 106.7 0.1 1.9e-14 53.7 0.2 3.8 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC37966.1 - 1.6e-27 95.3 1.6 1.9e-06 28.2 0.0 5.2 1 1 3 5 5 5 5 Ankyrin repeats (many copies) Ank PF00023.25 EGC37966.1 - 2e-25 87.3 8.5 0.00013 21.6 0.2 6.6 6 2 0 6 6 6 6 Ankyrin repeat Ank_5 PF13857.1 EGC37966.1 - 5.2e-16 58.3 1.3 0.0051 17.0 0.0 5.2 2 2 3 5 5 5 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC37966.1 - 5.4e-16 57.1 6.0 0.024 14.8 0.0 6.7 6 2 0 6 6 6 4 Ankyrin repeat zf-C2H2_4 PF13894.1 EGC37967.1 - 0.0039 17.4 2.9 0.0039 17.4 2.0 3.5 3 1 0 3 3 3 1 C2H2-type zinc finger DUF1982 PF09326.6 EGC37967.1 - 0.084 13.0 0.0 0.25 11.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF1982) Chlam_OMP3 PF03503.8 EGC37967.1 - 0.097 12.8 0.4 0.23 11.6 0.2 1.8 1 1 0 1 1 1 0 Chlamydia cysteine-rich outer membrane protein 3 IBR PF01485.16 EGC37967.1 - 0.36 10.7 14.2 0.62 9.9 4.8 3.0 2 1 1 3 3 3 0 IBR domain zf-Di19 PF05605.7 EGC37967.1 - 3.8 7.7 12.1 1.1 9.4 0.2 2.5 2 0 0 2 2 2 0 Drought induced 19 protein (Di19), zinc-binding AAA_29 PF13555.1 EGC37968.1 - 0.00019 20.9 0.1 0.00069 19.1 0.0 2.0 2 1 0 2 2 2 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC37968.1 - 0.00073 19.8 0.4 0.0013 18.9 0.1 1.7 1 1 0 1 1 1 1 ABC transporter DUF258 PF03193.11 EGC37968.1 - 0.00075 18.7 0.1 0.0011 18.1 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGC37968.1 - 0.00081 19.3 0.3 0.0017 18.2 0.2 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase AAA_16 PF13191.1 EGC37968.1 - 0.0023 17.9 0.0 0.0035 17.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Arf PF00025.16 EGC37968.1 - 0.0025 17.0 0.1 0.006 15.8 0.0 1.6 1 1 1 2 2 2 1 ADP-ribosylation factor family AAA_22 PF13401.1 EGC37968.1 - 0.0027 17.8 0.0 0.0058 16.7 0.0 1.6 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC37968.1 - 0.0036 17.5 1.3 0.074 13.3 0.0 2.7 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EGC37968.1 - 0.0048 17.3 0.0 0.013 16.0 0.0 1.8 2 1 0 2 2 2 1 Miro-like protein T2SE PF00437.15 EGC37968.1 - 0.0095 14.8 0.0 0.012 14.5 0.0 1.2 1 0 0 1 1 1 1 Type II/IV secretion system protein RNA_helicase PF00910.17 EGC37968.1 - 0.013 15.7 0.2 0.57 10.3 0.0 2.3 2 0 0 2 2 2 0 RNA helicase FtsK_SpoIIIE PF01580.13 EGC37968.1 - 0.013 14.9 0.0 0.018 14.4 0.0 1.2 1 0 0 1 1 1 0 FtsK/SpoIIIE family IIGP PF05049.8 EGC37968.1 - 0.019 13.8 0.0 0.026 13.3 0.0 1.2 1 0 0 1 1 1 0 Interferon-inducible GTPase (IIGP) AAA_10 PF12846.2 EGC37968.1 - 0.019 14.4 0.0 0.032 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA-like domain Dynamin_N PF00350.18 EGC37968.1 - 0.022 14.5 0.0 0.046 13.5 0.0 1.5 1 0 0 1 1 1 0 Dynamin family Zeta_toxin PF06414.7 EGC37968.1 - 0.024 13.7 0.0 0.052 12.6 0.0 1.5 2 0 0 2 2 2 0 Zeta toxin PPV_E1_C PF00519.12 EGC37968.1 - 0.028 13.0 0.0 0.038 12.6 0.0 1.1 1 0 0 1 1 1 0 Papillomavirus helicase AAA_PrkA PF08298.6 EGC37968.1 - 0.028 13.1 0.0 0.036 12.7 0.0 1.2 1 0 0 1 1 1 0 PrkA AAA domain cobW PF02492.14 EGC37968.1 - 0.045 13.1 0.4 0.084 12.3 0.3 1.5 1 1 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain DUF87 PF01935.12 EGC37968.1 - 0.052 13.3 0.7 0.16 11.8 0.1 1.9 1 1 1 2 2 2 0 Domain of unknown function DUF87 AAA_23 PF13476.1 EGC37968.1 - 0.058 13.7 4.0 0.038 14.3 1.4 2.0 1 1 1 2 2 2 0 AAA domain Sigma54_activat PF00158.21 EGC37968.1 - 0.097 12.1 0.0 0.13 11.7 0.0 1.2 1 0 0 1 1 1 0 Sigma-54 interaction domain CK_II_beta PF01214.13 EGC37968.1 - 0.13 11.7 0.2 0.18 11.2 0.1 1.2 1 0 0 1 1 1 0 Casein kinase II regulatory subunit AAA_17 PF13207.1 EGC37968.1 - 0.13 13.0 0.2 0.4 11.5 0.0 1.8 2 1 0 2 2 1 0 AAA domain AAA_28 PF13521.1 EGC37968.1 - 0.14 12.1 0.1 3.8 7.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain NACHT PF05729.7 EGC37968.1 - 0.15 11.6 0.0 0.35 10.5 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_24 PF13479.1 EGC37968.1 - 0.2 11.2 0.0 0.2 11.2 0.0 1.8 3 0 0 3 3 2 0 AAA domain Rhodanese PF00581.15 EGC37969.1 - 6.1e-33 113.5 0.0 1.7e-15 57.3 0.0 2.1 2 0 0 2 2 2 2 Rhodanese-like domain Molydop_binding PF01568.16 EGC37969.1 - 0.04 13.7 0.0 0.07 12.9 0.0 1.3 1 0 0 1 1 1 0 Molydopterin dinucleotide binding domain RRM_1 PF00076.17 EGC37970.1 - 3.6e-20 71.3 0.1 5.5e-20 70.7 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37970.1 - 3.7e-12 46.0 0.0 5.7e-12 45.4 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37970.1 - 2.9e-10 39.8 0.0 4.4e-10 39.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC37970.1 - 0.087 12.5 0.5 0.36 10.6 0.0 2.0 2 0 0 2 2 2 0 Limkain b1 RhoGAP PF00620.22 EGC37971.1 - 3.4e-40 137.1 0.3 1.1e-39 135.4 0.1 2.0 2 0 0 2 2 2 1 RhoGAP domain C2 PF00168.25 EGC37971.1 - 1.2e-15 57.1 0.0 3e-15 55.8 0.0 1.8 1 0 0 1 1 1 1 C2 domain PH PF00169.24 EGC37971.1 - 2.1e-08 34.3 4.0 3.5e-08 33.5 1.0 2.6 2 0 0 2 2 2 1 PH domain PH_3 PF14593.1 EGC37971.1 - 0.00011 22.0 0.6 0.00031 20.5 0.4 1.7 1 0 0 1 1 1 1 PH domain PH_9 PF15410.1 EGC37971.1 - 0.00023 21.3 0.0 0.00069 19.7 0.0 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PCI PF01399.22 EGC37972.1 - 2.5e-16 59.8 0.3 9e-16 58.1 0.2 2.1 1 1 0 1 1 1 1 PCI domain TPR_1 PF00515.23 EGC37972.1 - 0.0088 15.6 2.9 0.018 14.6 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat GFA PF04828.9 EGC37973.1 - 5.5e-05 23.0 0.1 5.5e-05 23.0 0.1 1.6 2 0 0 2 2 2 1 Glutathione-dependent formaldehyde-activating enzyme Cys_rich_CWC PF14375.1 EGC37973.1 - 0.045 13.6 0.7 0.072 13.0 0.5 1.3 1 0 0 1 1 1 0 Cysteine-rich CWC Nucleo_LEF-12 PF06256.6 EGC37973.1 - 0.089 12.5 0.3 0.1 12.3 0.2 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus LEF-12 protein zf-CSL PF05207.8 EGC37973.1 - 0.18 11.3 3.2 2 7.9 0.9 2.2 2 0 0 2 2 2 0 CSL zinc finger ABC2_membrane_3 PF12698.2 EGC37974.1 - 0.0098 14.9 7.3 0.013 14.5 5.0 1.1 1 0 0 1 1 1 1 ABC-2 family transporter protein ALAD PF00490.16 EGC37974.1 - 0.013 14.4 0.5 0.13 11.0 0.0 2.0 2 0 0 2 2 2 0 Delta-aminolevulinic acid dehydratase Acyltransferase PF01553.16 EGC37975.1 - 2.1e-05 23.9 0.0 3.5e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase TPPK_C PF12555.3 EGC37975.1 - 2.7 7.7 5.8 2.1 8.1 2.6 1.8 2 0 0 2 2 2 0 Thiamine pyrophosphokinase C terminal ubiquitin PF00240.18 EGC37976.1 - 1.1e-06 27.8 0.2 3.4e-06 26.3 0.2 1.9 1 0 0 1 1 1 1 Ubiquitin family UN_NPL4 PF11543.3 EGC37976.1 - 0.0099 16.1 0.2 0.046 13.9 0.1 2.2 1 0 0 1 1 1 1 Nuclear pore localisation protein NPL4 Zn_Tnp_IS1595 PF12760.2 EGC37976.1 - 0.038 13.7 6.2 0.07 12.9 4.3 1.4 1 0 0 1 1 1 0 Transposase zinc-ribbon domain Ribosomal_L37ae PF01780.14 EGC37976.1 - 0.12 12.2 1.6 0.27 11.1 1.1 1.5 1 0 0 1 1 1 0 Ribosomal L37ae protein family AT_hook PF02178.14 EGC37976.1 - 0.29 10.9 2.8 0.69 9.7 1.9 1.6 1 0 0 1 1 1 0 AT hook motif LysM PF01476.15 EGC37978.1 - 0.061 13.2 0.0 0.098 12.5 0.0 1.3 1 0 0 1 1 1 0 LysM domain Nodulin_late PF07127.6 EGC37978.1 - 3.4 7.8 7.1 4.2 7.5 0.0 3.1 3 0 0 3 3 3 0 Late nodulin protein Ank_2 PF12796.2 EGC37979.1 - 0.00016 21.9 0.1 0.0009 19.5 0.0 2.3 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC37979.1 - 0.00036 20.5 0.0 0.095 12.9 0.0 3.7 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGC37979.1 - 0.024 14.9 0.0 0.088 13.0 0.0 2.1 1 0 0 1 1 1 0 Ankyrin repeats (many copies) Ank PF00023.25 EGC37979.1 - 0.072 12.9 0.0 1.8 8.5 0.0 2.9 2 0 0 2 2 2 0 Ankyrin repeat RRM_1 PF00076.17 EGC37980.1 - 7.5e-07 28.6 0.0 1.6e-06 27.6 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC37980.1 - 4.5e-06 26.4 0.0 9.8e-06 25.3 0.0 1.6 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC37980.1 - 7.1e-06 25.9 0.0 1.4e-05 24.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) zf-CCCH PF00642.19 EGC37980.1 - 0.0074 15.9 5.0 0.016 14.8 3.5 1.6 1 0 0 1 1 1 1 Zinc finger C-x8-C-x5-C-x3-H type (and similar) SDA1 PF05285.7 EGC37980.1 - 0.042 13.1 30.0 0.072 12.3 20.8 1.4 1 0 0 1 1 1 0 SDA1 Nup35_RRM_2 PF14605.1 EGC37980.1 - 0.087 12.6 0.2 0.2 11.4 0.1 1.6 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif DUF3007 PF11460.3 EGC37980.1 - 0.27 11.3 2.6 13 5.9 0.0 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3007) Nop14 PF04147.7 EGC37980.1 - 1.5 6.6 35.2 2 6.2 24.4 1.2 1 0 0 1 1 1 0 Nop14-like family Daxx PF03344.10 EGC37980.1 - 1.9 6.8 34.4 2.5 6.4 23.8 1.2 1 0 0 1 1 1 0 Daxx Family Myb_DNA-bind_6 PF13921.1 EGC37980.1 - 2.6 8.2 12.8 2.4 8.3 0.3 3.9 3 1 1 4 4 4 0 Myb-like DNA-binding domain G-alpha PF00503.15 EGC37981.1 - 2.4e-96 322.7 3.7 3.5e-96 322.2 2.6 1.2 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC37981.1 - 4.3e-14 52.1 0.0 1.1e-09 37.8 0.0 2.7 2 0 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC37981.1 - 0.00092 18.4 0.3 0.24 10.5 0.0 2.4 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC37981.1 - 0.0061 17.0 0.6 0.61 10.6 0.2 2.8 2 1 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EGC37981.1 - 0.0093 16.7 0.2 0.029 15.2 0.1 2.0 1 1 0 1 1 1 1 AAA domain MMR_HSR1 PF01926.18 EGC37981.1 - 0.019 14.8 0.2 0.73 9.8 0.1 2.8 1 1 1 2 2 2 0 50S ribosome-binding GTPase Ribosomal_S13_N PF08069.7 EGC37982.1 - 1.5e-27 95.1 0.9 3.6e-27 93.9 0.1 1.9 2 0 0 2 2 2 1 Ribosomal S13/S15 N-terminal domain Ribosomal_S15 PF00312.17 EGC37982.1 - 2.1e-17 62.6 0.0 2.6e-17 62.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein S15 zf-4CXXC_R1 PF10497.4 EGC37982.1 - 0.073 13.2 0.0 0.11 12.6 0.0 1.2 1 0 0 1 1 1 0 Zinc-finger domain of monoamine-oxidase A repressor R1 HicB PF05534.7 EGC37982.1 - 0.082 12.4 0.0 0.15 11.6 0.0 1.4 1 0 0 1 1 1 0 HicB family TUG-UBL1 PF11470.3 EGC37983.1 - 1.2e-16 60.3 0.0 1.2e-16 60.3 0.0 2.4 2 0 0 2 2 2 1 GLUT4 regulating protein TUG UBX PF00789.15 EGC37983.1 - 6.7e-07 29.2 0.5 0.022 14.7 0.1 2.9 2 0 0 2 2 2 2 UBX domain DUF3670 PF12419.3 EGC37983.1 - 0.077 12.4 0.0 0.14 11.5 0.0 1.4 1 0 0 1 1 1 0 SNF2 Helicase protein SOG2 PF10428.4 EGC37983.1 - 5.8 5.4 39.8 2.5 6.6 1.2 2.1 2 0 0 2 2 2 0 RAM signalling pathway protein SHMT PF00464.14 EGC37984.1 - 8.7e-190 630.2 0.0 1e-189 630.0 0.0 1.0 1 0 0 1 1 1 1 Serine hydroxymethyltransferase Aminotran_5 PF00266.14 EGC37984.1 - 0.00031 19.6 0.0 0.00042 19.1 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Macro PF01661.16 EGC37984.1 - 0.0011 18.8 0.0 0.0083 16.0 0.0 2.3 2 0 0 2 2 2 1 Macro domain Beta_elim_lyase PF01212.16 EGC37984.1 - 0.069 12.2 0.0 0.12 11.4 0.0 1.5 1 1 0 1 1 1 0 Beta-eliminating lyase MFS_1 PF07690.11 EGC37985.1 - 2.5e-27 95.5 31.3 8.3e-27 93.8 21.8 1.8 1 1 1 2 2 2 1 Major Facilitator Superfamily MFS_2 PF13347.1 EGC37985.1 - 6e-09 34.8 20.5 2.6e-05 22.7 1.8 2.5 1 1 1 2 2 2 2 MFS/sugar transport protein Sugar_tr PF00083.19 EGC37985.1 - 1.5e-08 33.6 3.9 1.5e-08 33.6 2.7 2.1 1 1 1 2 2 2 1 Sugar (and other) transporter MFS_3 PF05977.8 EGC37985.1 - 0.0002 19.5 5.9 0.056 11.5 1.4 2.4 2 0 0 2 2 2 2 Transmembrane secretion effector Oxysterol_BP PF01237.13 EGC37986.1 - 1e-48 165.6 0.0 1.5e-48 165.1 0.0 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein zf-B_box PF00643.19 EGC37987.1 - 2.9e-06 27.0 3.6 4.2e-06 26.5 2.5 1.2 1 0 0 1 1 1 1 B-box zinc finger CortBP2 PF09727.4 EGC37987.1 - 0.0074 15.8 3.0 0.0081 15.6 2.1 1.2 1 0 0 1 1 1 1 Cortactin-binding protein-2 Sec20 PF03908.8 EGC37987.1 - 0.03 14.0 0.6 0.05 13.2 0.4 1.4 1 0 0 1 1 1 0 Sec20 SlyX PF04102.7 EGC37987.1 - 0.29 11.5 3.6 0.14 12.5 0.8 1.8 2 1 0 2 2 2 0 SlyX IMD PF08397.6 EGC37987.1 - 0.34 10.2 5.4 0.4 9.9 3.8 1.2 1 0 0 1 1 1 0 IRSp53/MIM homology domain zf-UBR PF02207.15 EGC37987.1 - 0.41 10.4 4.0 2.5 7.9 2.8 2.0 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) eIF-4B PF06273.6 EGC37987.1 - 0.72 8.5 2.3 0.8 8.3 1.6 1.0 1 0 0 1 1 1 0 Plant specific eukaryotic initiation factor 4B CCDC-167 PF15188.1 EGC37987.1 - 1.2 9.0 6.6 2.2 8.2 4.6 1.4 1 0 0 1 1 1 0 Coiled-coil domain-containing protein 167 GP41 PF00517.12 EGC37987.1 - 1.4 8.4 5.7 1.1 8.7 3.0 1.5 1 1 0 1 1 1 0 Retroviral envelope protein Syntaxin-6_N PF09177.6 EGC37988.1 - 5.1e-24 84.4 2.1 1.4e-23 83.1 0.0 2.4 2 1 0 2 2 2 1 Syntaxin 6, N-terminal SNARE PF05739.14 EGC37988.1 - 8.8e-10 38.1 3.5 8.8e-10 38.1 2.5 2.4 2 0 0 2 2 2 1 SNARE domain Use1 PF09753.4 EGC37988.1 - 6.8e-06 25.7 3.3 8.3e-06 25.4 2.3 1.3 1 0 0 1 1 1 1 Membrane fusion protein Use1 APG17 PF04108.7 EGC37988.1 - 0.008 15.0 3.4 0.028 13.2 0.0 2.1 1 1 1 2 2 2 1 Autophagy protein Apg17 RRF_GI PF12614.3 EGC37988.1 - 0.022 14.5 4.5 0.12 12.2 0.0 3.1 2 1 0 2 2 2 0 Ribosome recycling factor Microtub_assoc PF07989.6 EGC37988.1 - 0.031 14.0 3.2 1.6 8.5 0.9 2.7 2 0 0 2 2 2 0 Microtubule associated DUF443 PF04276.7 EGC37988.1 - 0.047 13.1 0.2 0.063 12.6 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF443) DUF1664 PF07889.7 EGC37988.1 - 0.35 10.6 2.7 0.96 9.2 0.1 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1664) Sec8_exocyst PF04048.9 EGC37988.1 - 0.48 10.0 5.9 0.77 9.3 1.8 2.3 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain YojJ PF10372.4 EGC37988.1 - 0.93 9.4 3.3 0.81 9.5 0.2 2.4 3 0 0 3 3 3 0 Bacterial membrane-spanning protein N-terminus TBPIP PF07106.8 EGC37988.1 - 1.2 8.6 13.1 0.23 10.9 1.1 3.0 1 1 2 3 3 3 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Prominin PF05478.6 EGC37988.1 - 1.7 6.0 11.3 9.5 3.6 3.8 3.0 1 1 0 2 2 2 0 Prominin FadA PF09403.5 EGC37988.1 - 2.3 8.2 7.3 2.6 8.0 0.1 2.3 2 0 0 2 2 2 0 Adhesion protein FadA DUF4559 PF15112.1 EGC37988.1 - 3.2 6.8 9.5 1.6 7.7 4.6 1.8 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) Enkurin PF13864.1 EGC37988.1 - 5.1 7.3 8.6 2 8.6 0.0 3.0 2 1 1 3 3 3 0 Calmodulin-binding CENP-Q PF13094.1 EGC37988.1 - 6.1 6.8 11.0 5 7.1 4.8 2.4 1 1 1 2 2 2 0 CENP-Q, a CENPA-CAD centromere complex subunit Mito_fiss_reg PF05308.6 EGC37989.1 - 2.6 7.3 8.8 0.14 11.4 2.2 1.8 2 0 0 2 2 2 0 Mitochondrial fission regulator TFIIA PF03153.8 EGC37989.1 - 5.8 6.7 26.4 9.1 6.0 18.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Metallophos PF00149.23 EGC37990.1 - 1e-42 145.8 1.5 1.3e-42 145.5 1.1 1.1 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase Clathrin PF00637.15 EGC37991.1 - 2.2e-20 72.7 23.3 5.6e-15 55.1 3.0 3.4 3 1 0 3 3 3 2 Region in Clathrin and VPS VPS11_C PF12451.3 EGC37991.1 - 2e-15 56.3 0.3 2e-15 56.3 0.2 2.2 2 0 0 2 2 2 1 Vacuolar protein sorting protein 11 C terminal zf-RING_2 PF13639.1 EGC37991.1 - 0.0013 18.5 9.0 0.0035 17.1 6.2 1.8 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC37991.1 - 0.0032 17.1 7.3 0.0074 15.9 5.0 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC37991.1 - 0.0047 16.9 8.3 0.011 15.7 5.7 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) TPR_11 PF13414.1 EGC37991.1 - 0.0048 16.5 1.9 0.01 15.4 0.0 2.4 2 0 0 2 2 2 1 TPR repeat zf-RING_6 PF14835.1 EGC37991.1 - 0.0057 16.4 0.7 0.013 15.2 0.5 1.5 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-rbx1 PF12678.2 EGC37991.1 - 0.0064 16.5 6.0 0.016 15.3 4.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger Aminotran_3 PF00202.16 EGC37991.1 - 0.07 11.9 0.0 0.17 10.7 0.0 1.6 1 0 0 1 1 1 0 Aminotransferase class-III zf-Apc11 PF12861.2 EGC37991.1 - 0.11 12.3 1.2 0.39 10.5 0.9 1.9 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_3 PF13920.1 EGC37991.1 - 0.11 12.1 5.9 0.3 10.7 4.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC37991.1 - 0.93 9.1 8.8 2.6 7.7 6.1 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) TPR_2 PF07719.12 EGC37991.1 - 2.7 8.1 8.2 1 9.4 0.9 3.4 3 0 0 3 3 3 0 Tetratricopeptide repeat CLU PF13236.1 EGC37992.1 - 8e-61 205.2 0.0 1.6e-60 204.2 0.0 1.6 1 0 0 1 1 1 1 Clustered mitochondria LRR_6 PF13516.1 EGC37992.1 - 8.7e-07 28.3 32.7 0.39 10.9 0.5 11.4 10 0 0 10 10 10 3 Leucine Rich repeat Peptidase_S9_N PF02897.10 EGC37993.1 - 1.2e-116 389.7 6.8 1.4e-116 389.4 4.7 1.1 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Peptidase_S9 PF00326.16 EGC37993.1 - 1.5e-62 210.5 0.0 2.6e-62 209.8 0.0 1.4 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_1 PF00561.15 EGC37993.1 - 0.027 14.0 0.0 0.17 11.4 0.0 1.9 1 1 1 2 2 2 0 alpha/beta hydrolase fold BAAT_C PF08840.6 EGC37993.1 - 0.056 13.1 0.0 0.29 10.8 0.0 2.2 1 1 0 1 1 1 0 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_5 PF12695.2 EGC37993.1 - 0.13 12.0 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_3 PF07859.8 EGC37993.1 - 0.18 11.3 0.0 1.2 8.6 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold PARP PF00644.15 EGC37994.1 - 1.2e-20 73.8 0.1 1.2e-20 73.8 0.1 2.7 3 0 0 3 3 3 1 Poly(ADP-ribose) polymerase catalytic domain WWE PF02825.15 EGC37994.1 - 6.2e-07 28.7 6.6 0.0012 18.1 0.2 3.1 3 0 0 3 3 3 2 WWE domain PSP1 PF04468.7 EGC37996.1 - 0.35 10.8 4.7 0.45 10.5 2.9 1.5 1 1 0 1 1 1 0 PSP1 C-terminal conserved region Bul1_C PF04426.7 EGC37996.1 - 0.84 8.7 16.8 1.1 8.3 11.6 1.1 1 0 0 1 1 1 0 Bul1 C terminus Phlebovirus_G1 PF07243.6 EGC37996.1 - 0.88 7.6 6.2 1.1 7.3 4.3 1.1 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 PRP1_N PF06424.7 EGC37996.1 - 0.97 9.7 10.0 0.27 11.5 1.2 2.3 2 0 0 2 2 2 0 PRP1 splicing factor, N-terminal DUF106 PF01956.11 EGC37996.1 - 3.6 7.1 6.1 6.4 6.2 4.2 1.3 1 0 0 1 1 1 0 Integral membrane protein DUF106 Neur_chan_memb PF02932.11 EGC37996.1 - 5.4 6.8 6.2 1.2 9.0 0.5 1.9 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Pkinase PF00069.20 EGC37997.1 - 1.2e-66 224.4 0.0 1.7e-66 224.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC37997.1 - 4.8e-27 94.6 0.0 6.8e-27 94.1 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase_C PF00433.19 EGC37997.1 - 3.5e-06 27.4 0.2 1.5e-05 25.4 0.2 2.2 1 0 0 1 1 1 1 Protein kinase C terminal domain Kinase-like PF14531.1 EGC37997.1 - 0.011 14.6 0.0 0.017 14.0 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Kdo PF06293.9 EGC37997.1 - 0.025 13.6 0.0 0.044 12.8 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family LRR_7 PF13504.1 EGC37998.1 - 6.8e-05 22.4 11.1 6.6 7.4 0.0 8.6 8 0 0 8 8 8 3 Leucine rich repeat LRR_6 PF13516.1 EGC37998.1 - 0.024 14.6 0.4 0.024 14.6 0.3 10.8 12 0 0 12 12 12 0 Leucine Rich repeat LRR_4 PF12799.2 EGC37998.1 - 1.5 8.4 54.9 0.064 12.9 0.5 8.5 7 2 1 8 8 8 0 Leucine Rich repeats (2 copies) FNIP PF05725.7 EGC37999.1 - 1.6e-68 226.3 57.0 7.3e-15 54.6 1.6 8.3 6 3 3 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 EGC37999.1 - 0.03 14.2 2.4 1.1 9.1 0.0 4.3 4 2 2 6 6 6 0 Protein of unknown function (DUF1769) Spidroin_MaSp PF11260.3 EGC37999.1 - 0.12 12.4 2.2 11 6.1 0.3 3.2 1 1 0 2 2 2 0 Major ampullate spidroin 1 and 2 Phospholip_B PF04916.8 EGC38000.1 - 1.7e-126 422.5 14.1 2.3e-126 422.1 9.8 1.1 1 0 0 1 1 1 1 Phospholipase B zf-C3HC PF07967.8 EGC38001.1 - 1.4e-32 112.2 0.1 1.4e-32 112.2 0.1 3.3 3 1 0 3 3 3 1 C3HC zinc finger-like Rsm1 PF08600.5 EGC38001.1 - 4.1e-13 48.9 11.5 1.2e-05 25.0 0.0 4.7 4 0 0 4 4 4 3 Rsm1-like RasGEF PF00617.14 EGC38002.1 - 3.5e-61 206.2 1.5 1.2e-60 204.4 1.0 2.0 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC38002.1 - 1.9e-29 101.7 3.5 7.3e-29 99.9 0.8 2.6 2 0 0 2 2 2 1 RasGEF N-terminal motif FNIP PF05725.7 EGC38004.1 - 4.2e-217 702.0 100.7 2.4e-15 56.1 0.1 14.4 4 3 17 21 21 21 20 FNIP Repeat Phage_min_tail PF05939.8 EGC38004.1 - 1.6e-06 28.0 0.0 37 4.3 0.0 8.2 7 3 3 10 10 10 0 Phage minor tail protein Bclx_interact PF08945.5 EGC38004.1 - 0.015 14.8 5.7 34 4.1 0.0 6.6 6 0 0 6 6 6 0 Bcl-x interacting, BH3 domain DUF3215 PF11503.3 EGC38004.1 - 0.037 13.6 3.2 14 5.3 0.0 5.3 7 1 1 8 8 8 0 Protein of unknown function (DUF3215) Noc2 PF03715.8 EGC38005.1 - 1.2e-91 306.7 7.8 1.2e-91 306.7 5.4 2.3 3 0 0 3 3 3 1 Noc2p family HEAT PF02985.17 EGC38005.1 - 0.059 13.4 0.1 0.25 11.5 0.1 2.0 1 0 0 1 1 1 0 HEAT repeat Metallophos PF00149.23 EGC38006.1 - 5.3e-08 32.4 0.0 1.3e-07 31.1 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_2 PF12850.2 EGC38006.1 - 0.0049 16.7 0.1 0.027 14.3 0.0 1.9 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain RRM_1 PF00076.17 EGC38007.1 - 2.6e-61 203.1 0.0 3.9e-23 80.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38007.1 - 7.2e-37 125.2 0.0 1.1e-12 47.7 0.0 3.2 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38007.1 - 7.2e-33 112.2 0.0 6.9e-11 41.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC38007.1 - 9.4e-07 28.6 1.0 0.005 16.6 0.1 2.6 2 1 0 2 2 2 2 RNA binding motif DUF3801 PF12687.2 EGC38007.1 - 0.017 14.7 3.3 0.023 14.2 2.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3801) PSP1 PF04468.7 EGC38007.1 - 0.021 14.8 2.2 0.044 13.7 0.1 2.1 2 0 0 2 2 2 0 PSP1 C-terminal conserved region Ribosomal_L32p PF01783.18 EGC38008.1 - 0.088 13.0 4.6 0.16 12.1 3.2 1.4 1 0 0 1 1 1 0 Ribosomal L32p protein family zf-C3HC4_3 PF13920.1 EGC38008.1 - 0.13 11.9 4.0 0.25 11.0 2.8 1.5 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Peptidase_C1 PF00112.18 EGC38010.1 - 4.9e-74 248.9 16.9 4.2e-72 242.5 11.7 2.2 1 1 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC38010.1 - 4.6e-13 49.2 3.4 7.6e-13 48.5 2.4 1.4 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC38010.1 - 0.0017 16.9 4.3 0.21 10.0 1.1 2.3 2 0 0 2 2 2 2 Peptidase C1-like family DUF605 PF04652.11 EGC38010.1 - 0.099 12.0 7.4 0.14 11.5 5.1 1.1 1 0 0 1 1 1 0 Vta1 like NIF PF03031.13 EGC38012.1 - 1.1e-52 177.9 0.4 1.1e-52 177.9 0.3 1.9 2 0 0 2 2 2 1 NLI interacting factor-like phosphatase Synaptobrevin PF00957.16 EGC38013.1 - 1.8e-28 97.9 3.6 2e-28 97.8 2.5 1.0 1 0 0 1 1 1 1 Synaptobrevin DUF912 PF06024.7 EGC38013.1 - 0.00025 21.0 0.4 0.00029 20.8 0.2 1.2 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Rifin_STEVOR PF02009.11 EGC38013.1 - 0.0022 17.6 0.1 0.0024 17.5 0.0 1.1 1 0 0 1 1 1 1 Rifin/stevor family UPF0258 PF06789.7 EGC38013.1 - 0.0037 17.3 1.7 0.0055 16.7 1.1 1.3 1 1 0 1 1 1 1 Uncharacterised protein family (UPF0258) Sec5 PF15469.1 EGC38013.1 - 0.026 14.2 0.1 0.029 14.1 0.1 1.1 1 0 0 1 1 1 0 Exocyst complex component Sec5 DUF515 PF04415.7 EGC38013.1 - 0.042 12.0 1.1 0.05 11.8 0.7 1.3 1 1 0 1 1 1 0 Protein of unknown function (DUF515) DUF2207 PF09972.4 EGC38013.1 - 0.045 12.3 0.0 0.045 12.3 0.0 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Shisa PF13908.1 EGC38013.1 - 2.4 8.2 4.4 1.7 8.8 1.9 1.6 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator MAPEG PF01124.13 EGC38014.1 - 3.9e-06 26.5 0.0 4.5e-06 26.2 0.0 1.2 1 0 0 1 1 1 1 MAPEG family Rad51 PF08423.6 EGC38015.1 - 3.6e-08 32.6 0.0 0.00014 20.8 0.0 2.2 2 0 0 2 2 2 2 Rad51 AAA_25 PF13481.1 EGC38015.1 - 0.00088 18.7 0.0 0.016 14.5 0.0 2.2 2 0 0 2 2 2 1 AAA domain KaiC PF06745.8 EGC38015.1 - 0.0022 17.1 0.2 0.0061 15.7 0.0 1.7 2 0 0 2 2 2 1 KaiC AAA_18 PF13238.1 EGC38015.1 - 0.0052 17.0 2.0 0.01 16.1 0.8 1.9 1 1 1 2 2 2 1 AAA domain PRK PF00485.13 EGC38015.1 - 0.013 15.0 0.0 0.026 14.0 0.0 1.8 1 1 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family Dynamin_N PF00350.18 EGC38015.1 - 0.087 12.6 1.7 0.096 12.4 0.2 1.9 2 1 0 2 2 2 0 Dynamin family RecA PF00154.16 EGC38015.1 - 0.11 11.5 0.1 0.24 10.4 0.0 1.7 2 0 0 2 2 2 0 recA bacterial DNA recombination protein MS_channel PF00924.13 EGC38017.1 - 1.5e-24 86.4 3.3 3.6e-24 85.2 2.3 1.6 1 0 0 1 1 1 1 Mechanosensitive ion channel DUF3899 PF13038.1 EGC38017.1 - 0.00017 21.6 1.5 0.0018 18.3 0.2 3.1 2 0 0 2 2 2 1 Domain of unknown function (DUF3899) PBP1_TM PF14812.1 EGC38017.1 - 0.0011 19.1 0.8 0.0033 17.6 0.6 1.8 1 0 0 1 1 1 1 Transmembrane domain of transglycosylase PBP1 at N-terminal FtsL PF04999.8 EGC38017.1 - 0.065 12.9 1.0 0.27 10.9 0.7 2.1 1 0 0 1 1 1 0 Cell division protein FtsL DUF912 PF06024.7 EGC38017.1 - 0.37 10.8 0.1 0.37 10.8 0.0 3.1 3 0 0 3 3 3 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF3671 PF12420.3 EGC38017.1 - 6.8 6.7 14.7 0.048 13.6 2.5 3.0 2 1 0 2 2 2 0 Protein of unknown function zf-HIT PF04438.11 EGC38018.1 - 1.8e-07 30.6 8.0 2.8e-07 30.0 5.5 1.3 1 0 0 1 1 1 1 HIT zinc finger Hydrolase_4 PF12146.3 EGC38019.1 - 6.8e-19 67.5 0.0 1.3e-18 66.5 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase Abhydrolase_6 PF12697.2 EGC38019.1 - 3.5e-15 56.5 0.0 4.7e-15 56.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_5 PF12695.2 EGC38019.1 - 1.9e-13 50.3 0.0 1e-12 48.0 0.0 2.0 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_2 PF02230.11 EGC38019.1 - 2.9e-07 30.1 0.1 0.0026 17.2 0.0 3.1 3 0 0 3 3 3 2 Phospholipase/Carboxylesterase AXE1 PF05448.7 EGC38019.1 - 0.0013 17.2 0.1 0.15 10.5 0.0 2.2 2 0 0 2 2 2 2 Acetyl xylan esterase (AXE1) Peptidase_S15 PF02129.13 EGC38019.1 - 0.0064 15.9 0.0 2.8 7.2 0.0 2.3 2 1 0 2 2 2 2 X-Pro dipeptidyl-peptidase (S15 family) Peptidase_S9 PF00326.16 EGC38019.1 - 0.019 14.1 0.0 0.077 12.2 0.0 2.0 2 0 0 2 2 2 0 Prolyl oligopeptidase family FSH1 PF03959.8 EGC38019.1 - 0.046 13.1 0.0 0.26 10.6 0.0 2.2 2 0 0 2 2 2 0 Serine hydrolase (FSH1) AAA PF00004.24 EGC38020.1 - 6.6e-56 188.1 0.0 1.7e-40 138.2 0.0 2.6 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC38020.1 - 8e-10 38.9 2.4 0.0033 17.5 0.2 4.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC38020.1 - 1.1e-09 38.5 0.1 0.00038 20.5 0.0 2.5 2 0 0 2 2 2 2 AAA ATPase domain AAA_14 PF13173.1 EGC38020.1 - 1.1e-09 38.2 0.0 1.3e-05 25.1 0.0 2.6 2 0 0 2 2 2 2 AAA domain AAA_5 PF07728.9 EGC38020.1 - 1.1e-08 34.8 0.0 0.00064 19.4 0.0 2.9 2 0 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGC38020.1 - 1.2e-08 35.7 0.0 0.01 16.6 0.0 2.7 2 0 0 2 2 2 2 AAA domain AAA_2 PF07724.9 EGC38020.1 - 7e-08 32.5 0.0 4.8e-06 26.6 0.0 2.6 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGC38020.1 - 8.5e-08 32.3 0.0 0.0054 16.8 0.0 3.1 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EGC38020.1 - 1.9e-07 31.0 0.0 0.017 15.0 0.0 2.5 2 0 0 2 2 2 2 AAA domain RuvB_N PF05496.7 EGC38020.1 - 2.3e-07 30.0 0.0 0.014 14.4 0.1 2.6 2 0 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_18 PF13238.1 EGC38020.1 - 2.5e-07 31.0 0.1 0.017 15.4 0.0 2.8 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EGC38020.1 - 3.9e-06 26.1 0.5 0.0094 15.1 0.1 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGC38020.1 - 1.6e-05 24.5 0.4 0.0029 17.3 0.1 2.8 3 0 0 3 3 2 1 Part of AAA domain ABC_tran PF00005.22 EGC38020.1 - 2.2e-05 24.7 0.1 0.38 11.0 0.1 2.7 2 1 0 2 2 2 2 ABC transporter Sigma54_activat PF00158.21 EGC38020.1 - 2.5e-05 23.7 0.1 0.12 11.8 0.0 2.6 2 0 0 2 2 2 2 Sigma-54 interaction domain AAA_25 PF13481.1 EGC38020.1 - 4e-05 23.1 1.2 0.76 9.1 0.0 3.3 2 1 1 3 3 3 2 AAA domain Arch_ATPase PF01637.13 EGC38020.1 - 4.9e-05 23.1 0.4 0.41 10.3 0.0 4.0 2 2 2 4 4 4 1 Archaeal ATPase AAA_3 PF07726.6 EGC38020.1 - 9.3e-05 22.0 0.0 0.63 9.6 0.0 2.8 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) Viral_helicase1 PF01443.13 EGC38020.1 - 0.00016 21.3 0.0 0.044 13.3 0.0 2.5 2 0 0 2 2 2 1 Viral (Superfamily 1) RNA helicase IstB_IS21 PF01695.12 EGC38020.1 - 0.00016 21.1 0.0 0.11 11.8 0.0 2.5 2 0 0 2 2 2 1 IstB-like ATP binding protein TIP49 PF06068.8 EGC38020.1 - 0.00016 20.5 0.0 0.097 11.3 0.0 2.3 2 0 0 2 2 2 2 TIP49 C-terminus NACHT PF05729.7 EGC38020.1 - 0.00017 21.2 4.1 0.41 10.2 0.1 3.8 4 0 0 4 4 4 2 NACHT domain AAA_24 PF13479.1 EGC38020.1 - 0.00018 21.1 0.5 0.26 10.8 0.1 2.6 2 0 0 2 2 2 2 AAA domain NB-ARC PF00931.17 EGC38020.1 - 0.0003 19.7 0.4 0.45 9.3 0.2 2.3 2 0 0 2 2 2 2 NB-ARC domain Zeta_toxin PF06414.7 EGC38020.1 - 0.00038 19.6 1.3 0.16 11.0 0.0 3.0 3 0 0 3 3 2 1 Zeta toxin KaiC PF06745.8 EGC38020.1 - 0.00041 19.5 0.2 0.061 12.4 0.0 2.6 2 0 0 2 2 2 1 KaiC UPF0079 PF02367.12 EGC38020.1 - 0.0008 19.0 0.0 0.21 11.2 0.0 2.4 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 Parvo_NS1 PF01057.12 EGC38020.1 - 0.0019 17.0 0.0 0.93 8.3 0.0 2.4 2 0 0 2 2 2 1 Parvovirus non-structural protein NS1 DUF2075 PF09848.4 EGC38020.1 - 0.0025 16.8 0.4 0.18 10.7 0.0 2.6 2 1 0 2 2 2 1 Uncharacterized conserved protein (DUF2075) Torsin PF06309.6 EGC38020.1 - 0.0027 17.5 0.1 2.1 8.2 0.0 2.5 2 0 0 2 2 2 1 Torsin Sigma54_activ_2 PF14532.1 EGC38020.1 - 0.0036 17.3 0.1 1.1 9.3 0.0 2.8 2 1 0 2 2 2 1 Sigma-54 interaction domain CDC48_2 PF02933.12 EGC38020.1 - 0.0037 16.8 0.3 0.025 14.2 0.0 2.4 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), domain 2 DUF815 PF05673.8 EGC38020.1 - 0.0038 16.1 0.2 0.11 11.4 0.0 3.1 4 0 0 4 4 4 1 Protein of unknown function (DUF815) CDC48_N PF02359.13 EGC38020.1 - 0.0039 17.1 0.0 0.06 13.2 0.0 2.8 2 1 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain AAA_11 PF13086.1 EGC38020.1 - 0.0056 16.2 0.0 0.24 10.9 0.0 2.3 2 0 0 2 2 2 1 AAA domain KTI12 PF08433.5 EGC38020.1 - 0.0085 15.3 0.3 1.4 8.0 0.0 2.4 2 0 0 2 2 2 1 Chromatin associated protein KTI12 AAA_28 PF13521.1 EGC38020.1 - 0.0093 15.9 0.1 5.1 7.0 0.0 2.4 2 0 0 2 2 2 0 AAA domain PhoH PF02562.11 EGC38020.1 - 0.019 14.1 0.0 1.6 7.9 0.0 2.3 2 0 0 2 2 2 0 PhoH-like protein AAA_30 PF13604.1 EGC38020.1 - 0.033 13.7 0.1 0.83 9.1 0.0 2.3 2 0 0 2 2 2 0 AAA domain AAA_29 PF13555.1 EGC38020.1 - 0.072 12.6 0.6 4.8 6.7 0.1 2.9 2 1 0 2 2 2 0 P-loop containing region of AAA domain CPT PF07931.7 EGC38020.1 - 0.073 12.6 0.1 2.4 7.7 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein Terpene_synth_C PF03936.11 EGC38021.1 - 5e-09 35.7 1.3 6.8e-09 35.3 0.9 1.3 1 0 0 1 1 1 1 Terpene synthase family, metal binding domain PP2C_2 PF13672.1 EGC38022.1 - 4.7e-05 22.9 0.0 0.00015 21.2 0.0 1.8 2 0 0 2 2 2 1 Protein phosphatase 2C PP2C PF00481.16 EGC38022.1 - 0.012 15.0 0.1 0.76 9.1 0.0 2.6 2 1 0 2 2 2 0 Protein phosphatase 2C Amidohydro_1 PF01979.15 EGC38026.1 - 4.1e-46 158.1 0.0 4.9e-46 157.9 0.0 1.1 1 0 0 1 1 1 1 Amidohydrolase family Amidohydro_5 PF13594.1 EGC38026.1 - 2.1e-08 33.8 0.0 7.1e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Amidohydrolase Amidohydro_3 PF07969.6 EGC38026.1 - 2.3e-07 30.4 0.0 0.00037 19.8 0.0 2.3 2 0 0 2 2 2 2 Amidohydrolase family Amidohydro_4 PF13147.1 EGC38026.1 - 0.0017 18.4 0.0 0.11 12.5 0.1 2.1 2 0 0 2 2 2 1 Amidohydrolase A_deaminase PF00962.17 EGC38026.1 - 0.0096 14.8 0.2 0.02 13.8 0.1 1.6 1 1 0 1 1 1 1 Adenosine/AMP deaminase DUF1192 PF06698.6 EGC38028.1 - 0.73 9.6 6.9 3.5 7.5 0.2 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1192) Reo_sigmaC PF04582.7 EGC38028.1 - 3.2 6.8 17.2 0.65 9.1 3.7 3.2 1 1 2 3 3 3 0 Reovirus sigma C capsid protein UVR PF02151.14 EGC38028.1 - 8 6.1 11.0 1.1 8.8 0.8 4.1 4 0 0 4 4 4 0 UvrB/uvrC motif Cyclin_N PF00134.18 EGC38029.1 - 3.2e-43 146.3 4.4 5.3e-43 145.6 1.3 2.2 2 0 0 2 2 2 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC38029.1 - 8.2e-36 122.5 1.7 1.6e-35 121.6 1.2 1.4 1 0 0 1 1 1 1 Cyclin, C-terminal domain Nodulin_late PF07127.6 EGC38031.1 - 0.81 9.8 4.8 1.3 9.1 3.3 1.5 1 1 0 1 1 1 0 Late nodulin protein ALMT PF11744.3 EGC38032.1 - 8.8e-39 133.2 7.6 8.8e-39 133.2 5.2 2.6 3 0 0 3 3 3 1 Aluminium activated malate transporter FUSC_2 PF13515.1 EGC38032.1 - 1.2e-15 57.5 13.2 1.2e-15 57.5 9.1 3.2 2 1 0 2 2 2 1 Fusaric acid resistance protein-like FUSC PF04632.7 EGC38032.1 - 2.9e-10 39.2 4.1 2.9e-10 39.2 2.9 2.4 3 0 0 3 3 3 2 Fusaric acid resistance protein family zf-RING_2 PF13639.1 EGC38033.1 - 1.3e-07 31.3 2.9 1.3e-07 31.3 2.0 1.9 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGC38033.1 - 0.0016 18.1 1.8 0.0016 18.1 1.2 2.6 2 1 0 2 2 2 1 zinc-RING finger domain PHD PF00628.24 EGC38033.1 - 0.0056 16.3 0.9 0.0056 16.3 0.6 2.5 2 0 0 2 2 2 1 PHD-finger zf-rbx1 PF12678.2 EGC38033.1 - 0.006 16.6 1.8 0.006 16.6 1.2 2.0 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC38033.1 - 0.007 15.9 1.7 0.007 15.9 1.2 2.3 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38033.1 - 0.021 14.8 1.6 0.021 14.8 1.1 2.6 1 1 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGC38033.1 - 0.042 13.6 4.3 0.31 10.9 3.0 2.4 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC38033.1 - 0.22 11.2 4.0 0.15 11.8 0.9 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DUF912 PF06024.7 EGC38033.1 - 1.1 9.3 7.5 0.18 11.8 0.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) TSA PF03249.8 EGC38033.1 - 5 5.5 7.1 0.7 8.3 0.5 2.0 2 0 0 2 2 2 0 Type specific antigen VWA_2 PF13519.1 EGC38034.1 - 4.3e-23 82.2 0.0 1.6e-16 60.9 0.0 3.3 3 0 0 3 3 3 2 von Willebrand factor type A domain VWA_CoxE PF05762.9 EGC38034.1 - 2.6e-06 26.7 0.0 0.0011 18.1 0.0 2.7 2 1 0 2 2 2 2 VWA domain containing CoxE-like protein F-box-like PF12937.2 EGC38034.1 - 1.1e-05 25.0 1.3 2.7e-05 23.8 0.9 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC38034.1 - 0.00046 19.7 1.6 0.0025 17.4 1.1 2.4 1 0 0 1 1 1 1 F-box domain fn3_3 PF14686.1 EGC38035.1 - 0.0083 16.2 1.8 0.26 11.4 0.0 2.9 3 0 0 3 3 3 1 Polysaccharide lyase family 4, domain II CUE PF02845.11 EGC38035.1 - 0.0087 15.5 0.1 2.9 7.4 0.0 2.6 2 0 0 2 2 2 2 CUE domain HC2 PF07382.6 EGC38035.1 - 5.4 6.8 6.9 9.4 6.0 4.8 1.4 1 0 0 1 1 1 0 Histone H1-like nucleoprotein HC2 Myosin_head PF00063.16 EGC38036.1 - 8.7e-124 414.0 7.9 8.7e-124 414.0 5.5 3.9 5 0 0 5 5 5 1 Myosin head (motor domain) MyTH4 PF00784.12 EGC38036.1 - 8.4e-45 151.4 0.1 3.6e-24 84.8 0.0 4.8 4 0 0 4 4 4 2 MyTH4 domain FERM_M PF00373.13 EGC38036.1 - 5.9e-15 55.5 0.0 3.6e-11 43.3 0.0 6.4 5 1 0 5 5 5 2 FERM central domain IQ PF00612.22 EGC38036.1 - 9.8e-07 27.8 3.5 0.0017 17.8 0.2 3.6 3 0 0 3 3 3 2 IQ calmodulin-binding motif CAF-1_p150 PF11600.3 EGC38036.1 - 0.00013 21.4 50.0 0.00013 21.4 34.6 9.4 9 2 0 10 10 10 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal OmpH PF03938.9 EGC38036.1 - 0.00085 19.2 9.8 0.00085 19.2 6.8 6.0 6 0 0 6 6 6 1 Outer membrane protein (OmpH-like) SH3_9 PF14604.1 EGC38036.1 - 0.0014 18.1 0.0 0.004 16.7 0.0 1.8 1 0 0 1 1 1 1 Variant SH3 domain S1 PF00575.18 EGC38037.1 - 2.4e-20 72.4 15.3 9.1e-08 32.0 0.1 7.1 7 0 0 7 7 7 4 S1 RNA binding domain Ycf1 PF05758.7 EGC38037.1 - 0.25 9.0 39.0 0.055 11.1 12.9 2.1 2 0 0 2 2 2 0 Ycf1 DUF3353 PF11833.3 EGC38038.1 - 3.5 7.0 8.0 9.2 5.6 1.4 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3353) Pkinase PF00069.20 EGC38039.1 - 3.6e-75 252.4 0.0 5.3e-75 251.9 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38039.1 - 7.3e-31 107.1 0.0 9.1e-31 106.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC38039.1 - 0.001 18.2 0.1 0.0016 17.5 0.0 1.2 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC38039.1 - 0.012 15.3 0.1 0.034 13.8 0.1 1.5 1 1 0 1 1 1 0 Phosphotransferase enzyme family Glyco_transf_8 PF01501.15 EGC38040.1 - 2.8e-23 82.5 1.1 5.3e-23 81.6 0.8 1.4 1 0 0 1 1 1 1 Glycosyl transferase family 8 Mannosyl_trans3 PF11051.3 EGC38040.1 - 0.00021 20.7 0.7 0.00038 19.8 0.1 1.6 1 1 1 2 2 2 1 Mannosyltransferase putative DUF843 PF05814.6 EGC38041.1 - 0.0058 16.3 0.2 0.0058 16.3 0.2 1.6 2 0 0 2 2 2 1 Baculovirus protein of unknown function (DUF843) SpoIIIAH PF12685.2 EGC38041.1 - 0.013 15.0 1.6 0.018 14.5 1.1 1.3 1 0 0 1 1 1 0 SpoIIIAH-like protein P12 PF12669.2 EGC38041.1 - 0.035 14.3 0.0 0.045 13.9 0.0 1.3 1 0 0 1 1 1 0 Virus attachment protein p12 family Mem_trans PF03547.13 EGC38041.1 - 0.088 11.0 3.4 0.097 10.9 2.4 1.0 1 0 0 1 1 1 0 Membrane transport protein PagP PF07017.6 EGC38041.1 - 0.17 11.1 4.8 0.26 10.5 3.3 1.3 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP DUF316 PF03761.10 EGC38041.1 - 1.1 8.5 14.7 0.023 14.0 3.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF316) 7TM_GPCR_Srw PF10324.4 EGC38041.1 - 2.6 7.0 5.7 0.59 9.1 1.6 1.5 1 1 0 2 2 2 0 Serpentine type 7TM GPCR chemoreceptor Srw Presenilin PF01080.12 EGC38041.1 - 3 6.5 7.9 3.7 6.2 5.5 1.1 1 0 0 1 1 1 0 Presenilin Shisa PF13908.1 EGC38041.1 - 4 7.5 11.4 20 5.3 7.9 1.9 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator Ctr PF04145.10 EGC38041.1 - 8.1 6.4 6.9 31 4.6 4.8 1.9 1 1 0 1 1 1 0 Ctr copper transporter family OTU PF02338.14 EGC38043.1 - 5.3e-18 65.7 2.5 8.1e-18 65.1 0.2 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease Gar1 PF04410.9 EGC38044.1 - 2.6e-26 91.9 10.9 2.8e-21 75.5 2.1 4.5 1 1 2 4 4 4 2 Gar1/Naf1 RNA binding region BRO1 PF03097.13 EGC38045.1 - 1.4e-102 343.2 8.0 1.4e-102 343.2 5.6 2.5 2 1 0 2 2 2 1 BRO1-like domain ALIX_LYPXL_bnd PF13949.1 EGC38045.1 - 5.1e-68 229.2 24.9 5.1e-68 229.2 17.3 2.5 3 0 0 3 3 3 1 ALIX V-shaped domain binding to HIV DUF4325 PF14213.1 EGC38045.1 - 0.026 14.1 0.1 0.11 12.1 0.1 2.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4325) KxDL PF10241.4 EGC38045.1 - 0.66 9.9 6.4 1.3 8.9 0.8 3.5 3 0 0 3 3 3 0 Uncharacterized conserved protein Pkinase PF00069.20 EGC38046.1 - 1.1e-28 100.1 3.5 1.2e-19 70.4 0.0 2.6 3 0 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38046.1 - 0.00018 20.6 0.0 0.56 9.2 0.0 2.4 2 0 0 2 2 2 2 Protein tyrosine kinase Mem_trans PF03547.13 EGC38046.1 - 0.18 10.0 0.8 0.17 10.1 0.6 1.1 1 0 0 1 1 1 0 Membrane transport protein CDC45 PF02724.9 EGC38046.1 - 0.82 7.6 13.5 1 7.3 9.4 1.1 1 0 0 1 1 1 0 CDC45-like protein Raftlin PF15250.1 EGC38046.1 - 1.9 6.9 10.9 2.5 6.5 7.6 1.1 1 0 0 1 1 1 0 Raftlin Hydrolase_3 PF08282.7 EGC38049.1 - 6.8e-64 215.8 0.0 7.7e-64 215.6 0.0 1.0 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase S6PP PF05116.8 EGC38049.1 - 3.7e-07 29.6 0.0 0.0013 18.1 0.0 2.1 2 0 0 2 2 2 2 Sucrose-6F-phosphate phosphohydrolase Hydrolase PF00702.21 EGC38049.1 - 1.7e-05 25.3 0.0 0.29 11.5 0.0 2.5 2 1 1 3 3 3 2 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC38049.1 - 0.00038 20.6 0.1 0.079 13.1 0.1 3.1 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase DUF2054 PF10218.4 EGC38050.1 - 3.9e-27 94.7 28.2 1.2e-20 73.6 10.6 2.5 1 1 1 2 2 2 2 Uncharacterized conserved protein (DUF2054) Ndc1_Nup PF09531.5 EGC38050.1 - 0.00098 17.6 16.9 0.0014 17.1 11.7 1.3 1 0 0 1 1 1 1 Nucleoporin protein Ndc1-Nup Utp14 PF04615.8 EGC38050.1 - 0.25 9.4 21.7 0.29 9.2 15.0 1.1 1 0 0 1 1 1 0 Utp14 protein ABC2_membrane_3 PF12698.2 EGC38050.1 - 1.1 8.2 18.9 1.5 7.7 13.1 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein CDC45 PF02724.9 EGC38050.1 - 1.3 7.0 17.8 1.8 6.4 12.4 1.3 1 0 0 1 1 1 0 CDC45-like protein DUF605 PF04652.11 EGC38050.1 - 1.4 8.1 22.7 1.9 7.8 15.7 1.2 1 0 0 1 1 1 0 Vta1 like Hid1 PF12722.2 EGC38050.1 - 5.5 4.5 31.0 7.1 4.1 21.5 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Methyltransf_3 PF01596.12 EGC38052.1 - 1.1e-69 233.6 0.4 1.3e-69 233.4 0.3 1.0 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGC38052.1 - 2.1e-13 51.0 0.0 3.3e-13 50.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38052.1 - 1e-07 32.5 0.1 2e-07 31.5 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38052.1 - 6.7e-05 22.5 0.1 9.9e-05 21.9 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC38052.1 - 0.0004 19.5 0.1 0.00048 19.2 0.0 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGC38052.1 - 0.0012 18.8 0.0 0.0021 18.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC38052.1 - 0.019 14.4 0.0 0.022 14.2 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) GCD14 PF08704.5 EGC38052.1 - 0.021 14.3 0.0 0.031 13.7 0.0 1.2 1 0 0 1 1 1 0 tRNA methyltransferase complex GCD14 subunit CmcI PF04989.7 EGC38052.1 - 0.053 12.8 0.0 0.15 11.3 0.0 1.7 2 0 0 2 2 2 0 Cephalosporin hydroxylase Methyltransf_12 PF08242.7 EGC38052.1 - 0.068 13.6 0.2 0.6 10.6 0.0 2.2 1 1 1 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38052.1 - 0.12 12.8 0.2 0.57 10.7 0.0 2.1 3 0 0 3 3 3 0 Methyltransferase domain efThoc1 PF11957.3 EGC38053.1 - 4.6e-61 206.8 30.7 4.8e-61 206.7 8.9 3.3 2 1 1 3 3 3 2 THO complex subunit 1 transcription elongation factor SSP160 PF06933.6 EGC38053.1 - 2.1 6.2 12.4 4.3 5.2 8.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 DUF3439 PF11921.3 EGC38053.1 - 2.4 7.9 8.1 3.3 7.4 3.9 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) LSM PF01423.17 EGC38054.1 - 2.1e-16 59.1 0.9 2.5e-16 58.9 0.6 1.0 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC38054.1 - 0.00051 19.9 0.0 0.00054 19.8 0.0 1.1 1 0 0 1 1 1 1 Ataxin 2 SM domain rRNA_proc-arch PF13234.1 EGC38055.1 - 6.4e-73 245.2 0.7 6.4e-73 245.2 0.5 1.7 2 0 0 2 2 2 1 rRNA-processing arch domain DSHCT PF08148.7 EGC38055.1 - 7.7e-56 188.1 0.0 1.8e-55 186.9 0.0 1.7 1 0 0 1 1 1 1 DSHCT (NUC185) domain DEAD PF00270.24 EGC38055.1 - 5e-22 78.1 0.0 1.3e-21 76.8 0.0 1.7 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38055.1 - 8.8e-05 22.2 0.0 0.00032 20.5 0.0 2.0 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Methyltransf_4 PF02390.12 EGC38056.1 - 6.1e-53 178.8 0.0 7.7e-53 178.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_18 PF12847.2 EGC38056.1 - 4.3e-05 24.0 0.0 6.4e-05 23.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38056.1 - 0.00028 20.5 0.0 0.00047 19.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC38056.1 - 0.0044 17.4 0.0 0.01 16.3 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC38056.1 - 0.0084 16.4 0.0 0.025 14.9 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_32 PF13679.1 EGC38056.1 - 0.017 14.8 0.0 0.028 14.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain MTS PF05175.9 EGC38056.1 - 0.026 13.9 0.0 0.043 13.2 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC38056.1 - 0.031 14.2 0.0 0.052 13.5 0.0 1.3 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38056.1 - 0.062 13.7 0.0 0.14 12.6 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain FNIP PF05725.7 EGC38057.1 - 2.4e-39 133.0 70.2 7.7e-12 44.9 0.4 11.6 9 2 2 12 12 12 9 FNIP Repeat DUF1769 PF08588.5 EGC38057.1 - 4.6e-05 23.2 3.0 3.5 7.6 0.1 5.2 4 1 1 5 5 5 2 Protein of unknown function (DUF1769) Dicty_CAR PF05462.6 EGC38058.1 - 1.9e-07 30.2 11.7 3.8e-07 29.2 8.1 1.5 1 0 0 1 1 1 1 Slime mold cyclic AMP receptor 7tm_2 PF00002.19 EGC38058.1 - 0.00098 18.2 9.2 0.0017 17.5 6.4 1.3 1 0 0 1 1 1 1 7 transmembrane receptor (Secretin family) Fz PF01392.17 EGC38058.1 - 0.11 12.9 1.8 0.19 12.1 1.3 1.4 1 0 0 1 1 1 0 Fz domain Fer4_3 PF12798.2 EGC38058.1 - 0.34 11.5 2.3 9.7 7.0 0.1 3.2 2 0 0 2 2 2 0 4Fe-4S binding domain Virul_fac_BrkB PF03631.10 EGC38058.1 - 4 6.7 10.1 0.45 9.8 2.2 2.4 1 1 0 2 2 2 0 Virulence factor BrkB Pkinase PF00069.20 EGC38059.1 - 1.2e-71 240.8 0.0 1.6e-71 240.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38059.1 - 1.3e-29 103.1 0.0 1.9e-29 102.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC38059.1 - 0.15 11.7 0.1 0.3 10.7 0.0 1.4 1 1 0 1 1 1 0 Phosphotransferase enzyme family DUF2149 PF09919.4 EGC38059.1 - 4.8 7.3 5.9 21 5.2 0.1 3.0 3 0 0 3 3 3 0 Uncharacterized conserved protein (DUF2149) Med18 PF09637.5 EGC38060.1 - 6.1e-07 29.2 0.1 6.6e-07 29.1 0.1 1.3 1 0 0 1 1 1 1 Med18 protein MFS_1 PF07690.11 EGC38061.1 - 4.1e-41 140.8 51.6 4.7e-32 111.0 20.6 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC38061.1 - 3.8e-13 48.8 23.4 7.2e-13 47.9 16.2 1.4 1 1 0 1 1 1 1 Sugar (and other) transporter ATG22 PF11700.3 EGC38061.1 - 0.025 13.0 18.4 0.0053 15.2 3.1 2.9 1 1 1 2 2 2 0 Vacuole effluxer Atg22 like DUF4337 PF14235.1 EGC38061.1 - 3.4 7.4 6.5 0.17 11.7 0.3 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) FYVE PF01363.16 EGC38062.1 - 2.1e-17 62.7 10.1 4.6e-17 61.6 7.0 1.6 1 0 0 1 1 1 1 FYVE zinc finger Arrestin_N PF00339.24 EGC38062.1 - 3.1e-06 27.0 6.2 1.4e-05 24.9 0.9 2.9 2 1 0 2 2 2 1 Arrestin (or S-antigen), N-terminal domain Arrestin_C PF02752.17 EGC38062.1 - 6.9e-05 22.9 0.6 6.9e-05 22.9 0.4 4.3 4 3 0 4 4 4 2 Arrestin (or S-antigen), C-terminal domain FNIP PF05725.7 EGC38063.1 - 5.7e-43 144.6 57.2 1.5e-11 44.0 0.3 11.4 8 2 5 14 14 14 10 FNIP Repeat CP_ATPgrasp_2 PF14403.1 EGC38064.1 - 0.0079 14.8 0.0 0.0098 14.5 0.0 1.0 1 0 0 1 1 1 1 Circularly permuted ATP-grasp type 2 LRR_4 PF12799.2 EGC38064.1 - 0.062 12.9 1.0 0.23 11.1 0.7 1.9 1 1 0 1 1 1 0 Leucine Rich repeats (2 copies) Mog1 PF04603.7 EGC38065.1 - 6e-28 97.5 0.4 8.2e-28 97.1 0.3 1.2 1 0 0 1 1 1 1 Ran-interacting Mog1 protein DUF4559 PF15112.1 EGC38065.1 - 1.3 8.0 5.9 1.7 7.7 4.1 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4559) Lung_7-TM_R PF06814.8 EGC38066.1 - 4e-28 98.2 8.8 5e-28 97.9 6.1 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor BatD PF13584.1 EGC38066.1 - 0.17 10.4 0.0 0.17 10.4 0.0 1.5 2 0 0 2 2 2 0 Oxygen tolerance Lung_7-TM_R PF06814.8 EGC38067.1 - 3.7e-11 42.5 7.7 4.4e-11 42.2 5.3 1.1 1 0 0 1 1 1 1 Lung seven transmembrane receptor DUF3792 PF12670.2 EGC38067.1 - 0.31 10.9 4.1 0.97 9.3 2.7 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3792) DNA_primase_S PF01896.14 EGC38068.1 - 2.7e-41 140.7 0.9 4.5e-41 140.0 0.6 1.3 1 0 0 1 1 1 1 Eukaryotic and archaeal DNA primase small subunit BP28CT PF08146.7 EGC38069.1 - 1.4e-29 102.8 10.8 2.7e-17 62.9 0.2 4.6 3 1 1 4 4 4 2 BP28CT (NUC211) domain HEAT PF02985.17 EGC38069.1 - 1.9e-05 24.3 0.5 9 6.6 0.0 6.2 6 0 0 6 6 6 2 HEAT repeat HEAT_EZ PF13513.1 EGC38069.1 - 0.026 15.0 1.7 2.7e+02 2.2 0.0 6.2 7 0 0 7 7 7 0 HEAT-like repeat PBP1_TM PF14812.1 EGC38069.1 - 0.43 10.9 10.2 0.14 12.4 1.6 2.6 2 0 0 2 2 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DDE_Tnp_4 PF13359.1 EGC38070.1 - 5.8e-16 58.4 0.0 6.9e-16 58.2 0.0 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC38070.1 - 0.0035 16.9 0.1 0.0098 15.4 0.0 1.6 1 1 0 1 1 1 1 Transposase DDE domain CBM49 PF09478.5 EGC38071.1 - 8.7e-16 57.7 0.2 1.3e-15 57.2 0.1 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM_2 PF00553.14 EGC38071.1 - 0.0023 17.9 0.6 0.0037 17.2 0.4 1.3 1 0 0 1 1 1 1 Cellulose binding domain AP3B1_C PF14796.1 EGC38071.1 - 0.078 12.6 0.2 0.13 11.8 0.2 1.3 1 0 0 1 1 1 0 Clathrin-adaptor complex-3 beta-1 subunit C-terminal FNIP PF05725.7 EGC38072.1 - 1.4e-69 229.7 48.8 3.1e-13 49.4 0.0 7.8 3 2 7 10 10 10 10 FNIP Repeat zf-C3HC4_4 PF15227.1 EGC38072.1 - 1.5e-07 31.1 8.5 1.5e-07 31.1 5.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-B_box PF00643.19 EGC38072.1 - 9.2e-07 28.6 10.9 9.2e-07 28.6 7.6 3.3 3 1 0 3 3 3 1 B-box zinc finger zf-RING_5 PF14634.1 EGC38072.1 - 0.0049 16.5 7.4 0.0049 16.5 5.1 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC38072.1 - 0.01 15.8 7.9 0.01 15.8 5.4 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) B12D PF06522.6 EGC38073.1 - 2e-06 27.3 0.0 2.3e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 NADH-ubiquinone reductase complex 1 MLRQ subunit PetM PF08041.6 EGC38073.1 - 0.19 11.2 1.1 0.31 10.5 0.8 1.4 1 0 0 1 1 1 0 PetM family of cytochrome b6f complex subunit 7 RhoGAP PF00620.22 EGC38074.1 - 2.7e-39 134.2 0.3 9e-39 132.5 0.0 2.1 2 0 0 2 2 2 1 RhoGAP domain RhoGEF PF00621.15 EGC38074.1 - 3.8e-32 111.6 0.3 3.8e-32 111.6 0.2 3.9 2 2 1 3 3 3 1 RhoGEF domain PH PF00169.24 EGC38074.1 - 3.8e-30 104.1 4.6 1.1e-18 67.3 0.6 2.6 2 0 0 2 2 2 2 PH domain PH_11 PF15413.1 EGC38074.1 - 0.00021 21.4 7.1 0.0051 17.0 0.4 3.4 3 0 0 3 3 3 2 Pleckstrin homology domain DUF1664 PF07889.7 EGC38074.1 - 3.8 7.3 12.2 0.056 13.2 1.8 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1664) TMEM51 PF15345.1 EGC38076.1 - 0.0016 18.1 12.0 0.0021 17.7 8.3 1.1 1 0 0 1 1 1 1 Transmembrane protein 51 FPN1 PF06963.7 EGC38076.1 - 0.0034 15.8 1.8 0.0042 15.5 1.3 1.1 1 0 0 1 1 1 1 Ferroportin1 (FPN1) Pol_alpha_B_N PF08418.5 EGC38076.1 - 0.0052 16.3 20.3 0.007 15.9 14.1 1.1 1 0 0 1 1 1 1 DNA polymerase alpha subunit B N-terminal Tfb4 PF03850.9 EGC38076.1 - 0.0069 15.6 2.9 0.01 15.0 2.0 1.2 1 0 0 1 1 1 1 Transcription factor Tfb4 FAM176 PF14851.1 EGC38076.1 - 0.0082 15.8 0.5 0.016 14.8 0.3 1.6 1 0 0 1 1 1 1 FAM176 family IncA PF04156.9 EGC38076.1 - 0.011 15.3 10.8 0.65 9.5 9.4 1.9 1 1 1 2 2 2 0 IncA protein CytochromB561_N PF09786.4 EGC38076.1 - 0.011 14.1 27.7 0.014 13.9 19.2 1.1 1 0 0 1 1 1 0 Cytochrome B561, N terminal Ly49 PF08391.5 EGC38076.1 - 0.012 15.7 1.7 0.012 15.7 1.1 1.7 2 0 0 2 2 1 0 Ly49-like protein, N-terminal region PIG-P PF08510.7 EGC38076.1 - 0.017 14.7 0.3 0.026 14.1 0.2 1.3 1 0 0 1 1 1 0 PIG-P SCIMP PF15050.1 EGC38076.1 - 0.03 14.2 0.8 0.03 14.2 0.5 2.0 2 0 0 2 2 2 0 SCIMP protein 7TM_GPCR_Sru PF10322.4 EGC38076.1 - 0.055 12.5 2.0 0.082 12.0 1.4 1.4 1 1 0 1 1 1 0 Serpentine type 7TM GPCR chemoreceptor Sru FHIPEP PF00771.15 EGC38076.1 - 0.067 11.5 1.1 0.087 11.1 0.8 1.1 1 0 0 1 1 1 0 FHIPEP family DUF788 PF05620.6 EGC38076.1 - 0.068 13.0 2.5 0.12 12.2 1.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF788) Pex16 PF08610.5 EGC38076.1 - 0.082 11.8 7.3 0.11 11.4 5.1 1.3 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) GnHR_trans PF12369.3 EGC38076.1 - 0.095 13.1 0.9 0.095 13.1 0.6 2.7 2 1 0 2 2 1 0 Gonadotropin hormone receptor transmembrane region SelP_N PF04592.9 EGC38076.1 - 0.1 11.9 12.6 0.55 9.5 1.6 2.1 2 0 0 2 2 2 0 Selenoprotein P, N terminal region SID-1_RNA_chan PF13965.1 EGC38076.1 - 0.16 10.1 2.4 0.25 9.4 1.7 1.2 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Folate_carrier PF01770.13 EGC38076.1 - 0.17 10.3 3.2 0.23 9.9 2.2 1.1 1 0 0 1 1 1 0 Reduced folate carrier PEX11 PF05648.9 EGC38076.1 - 0.21 10.8 3.5 0.33 10.1 2.4 1.3 1 0 0 1 1 1 0 Peroxisomal biogenesis factor 11 (PEX11) Sporozoite_P67 PF05642.6 EGC38076.1 - 0.27 9.0 14.5 0.35 8.6 10.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen DivIC PF04977.10 EGC38076.1 - 0.32 10.5 12.1 0.52 9.8 8.4 1.4 1 0 0 1 1 1 0 Septum formation initiator MscS_TM PF12794.2 EGC38076.1 - 0.34 9.4 5.3 0.49 8.9 3.7 1.1 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 Mcm10 PF09332.6 EGC38076.1 - 0.47 9.7 14.5 0.58 9.4 10.0 1.1 1 0 0 1 1 1 0 Mcm10 replication factor UPF0118 PF01594.11 EGC38076.1 - 0.53 9.2 1.9 0.69 8.8 1.3 1.1 1 0 0 1 1 1 0 Domain of unknown function DUF20 Neur_chan_memb PF02932.11 EGC38076.1 - 0.65 9.8 9.9 0.93 9.3 6.9 1.4 1 1 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF2215 PF10225.4 EGC38076.1 - 0.65 9.3 6.3 1 8.7 4.3 1.3 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2215) YABBY PF04690.8 EGC38076.1 - 0.72 10.0 6.7 0.09 13.0 1.6 1.7 2 0 0 2 2 2 0 YABBY protein DUF2232 PF09991.4 EGC38076.1 - 0.84 8.5 4.8 1 8.2 3.4 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) Tetraspannin PF00335.15 EGC38076.1 - 0.92 8.7 4.6 1.3 8.2 3.2 1.3 1 1 0 1 1 1 0 Tetraspanin family DUF702 PF05142.7 EGC38076.1 - 1.3 9.1 7.7 2.3 8.3 5.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF702) UPF0542 PF15086.1 EGC38076.1 - 1.4 8.6 3.8 3.8 7.2 2.6 1.8 1 1 0 1 1 1 0 Uncharacterised protein family UPF0542 YjgP_YjgQ PF03739.9 EGC38076.1 - 1.8 7.2 5.6 0.58 8.8 2.1 1.4 2 0 0 2 2 2 0 Predicted permease YjgP/YjgQ family EphA2_TM PF14575.1 EGC38076.1 - 2.1 8.7 4.2 0.54 10.6 0.7 1.7 2 0 0 2 2 1 0 Ephrin type-A receptor 2 transmembrane domain Ctr PF04145.10 EGC38076.1 - 2.6 8.0 7.8 4.7 7.2 5.4 1.5 1 1 0 1 1 1 0 Ctr copper transporter family CENP-L PF13092.1 EGC38076.1 - 2.7 7.7 11.1 1e+03 -0.7 7.7 2.2 1 1 0 1 1 1 0 Kinetochore complex Sim4 subunit Fta1 RAB3GAP2_N PF14655.1 EGC38076.1 - 4.4 6.1 13.5 1.8 7.4 7.8 1.5 1 1 1 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus PHD_3 PF13922.1 EGC38076.1 - 5 7.4 11.3 12 6.2 7.8 1.7 1 0 0 1 1 1 0 PHD domain of transcriptional enhancer, Asx EIIBC-GUT_N PF03612.9 EGC38076.1 - 5.7 6.5 6.4 3.3 7.2 3.0 1.6 2 0 0 2 2 2 0 Sorbitol phosphotransferase enzyme II N-terminus DUF3513 PF12026.3 EGC38076.1 - 5.8 6.3 16.2 1.1 8.7 8.3 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3513) SLD3 PF08639.5 EGC38076.1 - 7.1 5.1 27.5 9.4 4.7 19.1 1.1 1 0 0 1 1 1 0 DNA replication regulator SLD3 WBP-1 PF11669.3 EGC38076.1 - 7.2 6.7 10.0 25 4.9 6.9 1.9 1 1 0 1 1 1 0 WW domain-binding protein 1 Shisa PF13908.1 EGC38076.1 - 7.6 6.6 12.3 16 5.6 8.5 1.7 1 1 0 1 1 1 0 Wnt and FGF inhibitory regulator GRAM PF02893.15 EGC38077.1 - 0.11 12.0 1.6 6.6 6.3 0.1 2.4 2 0 0 2 2 2 0 GRAM domain EGF_2 PF07974.8 EGC38078.1 - 0.028 14.5 12.8 0.052 13.7 8.9 1.5 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.7 EGC38079.1 - 3.1e-25 87.8 41.0 6.8e-07 29.1 0.0 7.3 7 1 1 8 8 8 5 FNIP Repeat Striatin PF08232.7 EGC38079.1 - 0.012 15.9 0.9 0.018 15.3 0.6 1.2 1 0 0 1 1 1 0 Striatin family bZIP_1 PF00170.16 EGC38079.1 - 0.077 12.9 2.3 0.16 11.9 1.6 1.5 1 0 0 1 1 1 0 bZIP transcription factor DUF2681 PF10883.3 EGC38079.1 - 0.19 11.9 3.7 0.38 11.0 2.6 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) EGF_2 PF07974.8 EGC38080.1 - 0.0025 17.9 11.0 0.006 16.7 7.7 1.7 1 0 0 1 1 1 1 EGF-like domain SKG6 PF08693.5 EGC38080.1 - 0.016 14.5 0.4 0.032 13.5 0.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain TMEMspv1-c74-12 PF11044.3 EGC38080.1 - 0.025 14.1 3.8 1.4 8.4 0.1 2.4 2 0 0 2 2 2 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein hEGF PF12661.2 EGC38080.1 - 0.15 12.2 2.4 0.39 10.9 1.7 1.8 1 0 0 1 1 1 0 Human growth factor-like EGF DUF3244 PF11589.3 EGC38080.1 - 0.35 10.6 4.5 0.67 9.6 0.9 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF3244) Laminin_EGF PF00053.19 EGC38080.1 - 8.2 6.4 12.9 0.43 10.5 4.7 2.1 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) Spc97_Spc98 PF04130.8 EGC38081.1 - 5.4e-117 391.3 36.2 5.4e-117 391.3 25.1 2.8 3 0 0 3 3 3 1 Spc97 / Spc98 family Oxidored_q6 PF01058.17 EGC38082.1 - 8.1e-22 77.2 0.2 1e-21 76.9 0.1 1.1 1 0 0 1 1 1 1 NADH ubiquinone oxidoreductase, 20 Kd subunit FA_desaturase PF00487.19 EGC38083.1 - 1.6e-41 142.4 11.9 1.6e-41 142.4 8.2 1.5 1 1 1 2 2 2 1 Fatty acid desaturase Cyt-b5 PF00173.23 EGC38083.1 - 6e-25 86.8 0.0 1.2e-24 85.9 0.0 1.5 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain CitMHS PF03600.11 EGC38084.1 - 3.2e-71 239.7 0.0 5.3e-69 232.4 0.0 2.0 1 1 1 2 2 2 2 Citrate transporter ArsB PF02040.10 EGC38084.1 - 6.1e-15 55.1 30.9 5.4e-14 51.9 9.4 2.2 2 0 0 2 2 2 2 Arsenical pump membrane protein LolA PF03548.10 EGC38085.1 - 0.032 13.8 2.3 0.062 12.9 1.0 1.9 2 0 0 2 2 2 0 Outer membrane lipoprotein carrier protein LolA Ras PF00071.17 EGC38087.1 - 3e-08 33.2 1.7 2.3e-07 30.3 1.2 2.1 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC38087.1 - 5.9e-05 23.5 2.7 0.00012 22.5 1.6 1.8 1 1 0 1 1 1 1 Miro-like protein Septin PF00735.13 EGC38087.1 - 0.00051 19.1 0.3 0.00051 19.1 0.2 2.1 2 1 0 2 2 2 1 Septin AAA_17 PF13207.1 EGC38087.1 - 0.0016 19.2 0.0 0.0043 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC38087.1 - 0.0032 17.4 0.0 0.0067 16.4 0.0 1.5 2 0 0 2 2 1 1 AAA domain MMR_HSR1 PF01926.18 EGC38087.1 - 0.0046 16.9 5.5 0.013 15.4 3.8 2.0 1 1 0 1 1 1 1 50S ribosome-binding GTPase Caleosin PF05042.8 EGC38087.1 - 0.008 15.7 0.0 0.017 14.6 0.0 1.5 1 0 0 1 1 1 1 Caleosin related protein PduV-EutP PF10662.4 EGC38087.1 - 0.0087 15.5 0.1 0.018 14.5 0.0 1.6 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation AAA_18 PF13238.1 EGC38087.1 - 0.0092 16.2 1.1 0.035 14.4 0.7 2.2 1 1 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC38087.1 - 0.016 15.3 0.8 0.11 12.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_14 PF13173.1 EGC38087.1 - 0.058 13.3 4.0 0.28 11.0 2.8 2.4 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC38087.1 - 0.073 12.7 2.2 0.094 12.3 1.2 1.6 1 1 0 1 1 1 0 Archaeal ATPase T2SE PF00437.15 EGC38087.1 - 0.084 11.7 0.6 0.12 11.2 0.4 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_33 PF13671.1 EGC38087.1 - 0.11 12.4 0.0 0.18 11.6 0.0 1.4 1 0 0 1 1 1 0 AAA domain GTP_EFTU PF00009.22 EGC38087.1 - 0.12 11.7 2.3 0.19 11.1 1.6 1.8 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGC38087.1 - 0.15 12.0 0.0 0.25 11.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MH2 PF03166.9 EGC38087.1 - 0.34 10.6 3.0 4.5 7.0 0.7 2.3 2 1 0 2 2 2 0 MH2 domain ABC_tran PF00005.22 EGC38087.1 - 3.1 8.1 7.8 5.3 7.3 5.4 1.7 1 1 0 1 1 1 0 ABC transporter SIS PF01380.17 EGC38088.1 - 7.1e-41 138.8 0.9 5.1e-21 74.6 0.0 2.5 2 0 0 2 2 2 2 SIS domain GATase_6 PF13522.1 EGC38088.1 - 4.3e-23 81.7 0.0 8.4e-23 80.7 0.0 1.5 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_7 PF13537.1 EGC38088.1 - 4.4e-19 68.4 0.0 1.1e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGC38088.1 - 7.5e-17 61.0 0.1 5.5e-12 45.0 0.0 2.8 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_4 PF13230.1 EGC38088.1 - 0.00076 18.2 0.3 0.0014 17.3 0.2 1.4 1 0 0 1 1 1 1 Glutamine amidotransferases class-II Transthyretin PF00576.16 EGC38089.1 - 1.1e-32 112.2 0.1 1.3e-32 111.9 0.1 1.1 1 0 0 1 1 1 1 HIUase/Transthyretin family CarboxypepD_reg PF13620.1 EGC38089.1 - 0.00012 22.0 0.0 0.00016 21.6 0.0 1.2 1 0 0 1 1 1 1 Carboxypeptidase regulatory-like domain DUF4480 PF13715.1 EGC38089.1 - 0.0087 16.0 0.1 0.015 15.2 0.0 1.4 1 1 0 1 1 1 1 Domain of unknown function (DUF4480) Cna_B PF05738.8 EGC38089.1 - 0.029 14.1 0.3 0.047 13.4 0.2 1.4 1 0 0 1 1 1 0 Cna protein B-type domain Ubiquitin_2 PF14560.1 EGC38089.1 - 0.1 12.8 0.1 0.15 12.3 0.0 1.3 1 0 0 1 1 1 0 Ubiquitin-like domain Ribonuclease_T2 PF00445.13 EGC38090.1 - 0.1 12.1 0.6 0.1 12.2 0.4 1.1 1 0 0 1 1 1 0 Ribonuclease T2 family Lactamase_B_4 PF13691.1 EGC38091.1 - 0.044 13.2 0.0 0.067 12.6 0.0 1.3 1 0 0 1 1 1 0 tRNase Z endonuclease Branch PF02485.16 EGC38092.1 - 7.9e-10 38.2 3.5 3.4e-09 36.2 2.4 2.0 1 1 0 1 1 1 1 Core-2/I-Branching enzyme C9orf72-like PF15019.1 EGC38092.1 - 0.072 12.3 5.0 0.02 14.1 0.9 2.0 2 0 0 2 2 2 0 C9orf72-like protein family TLD PF07534.11 EGC38093.1 - 2.8e-16 59.7 3.2 2.8e-16 59.7 2.2 1.8 2 0 0 2 2 2 1 TLD BTB_2 PF02214.17 EGC38093.1 - 9e-14 51.4 0.1 2.3e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 BTB/POZ domain zf-C3HC4_2 PF13923.1 EGC38094.1 - 2.9e-11 43.2 14.0 4.8e-11 42.4 9.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC38094.1 - 2.4e-09 36.7 13.8 3.1e-09 36.3 9.6 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC38094.1 - 2.3e-08 33.7 17.1 3.1e-08 33.3 11.9 1.2 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC38094.1 - 2.2e-07 30.4 13.4 3.7e-07 29.7 9.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38094.1 - 4.2e-06 26.3 14.3 7.3e-06 25.6 9.9 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC38094.1 - 2.1e-05 24.2 13.3 6.3e-05 22.7 9.4 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC38094.1 - 0.00014 21.4 10.5 0.00024 20.7 1.9 2.2 2 0 0 2 2 2 1 RING-type zinc-finger zf-RING_4 PF14570.1 EGC38094.1 - 0.011 15.2 9.0 0.011 15.2 6.3 2.2 2 0 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGC38094.1 - 0.012 15.6 11.8 0.036 14.1 8.2 1.7 1 1 0 1 1 1 0 RING-H2 zinc finger Prok-RING_4 PF14447.1 EGC38094.1 - 0.026 14.0 16.6 0.05 13.1 7.1 2.7 1 1 1 2 2 2 0 Prokaryotic RING finger family 4 zf-Apc11 PF12861.2 EGC38094.1 - 0.47 10.3 9.3 0.65 9.8 6.4 1.2 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGC38094.1 - 1.7 8.4 7.7 3.3 7.5 5.4 1.6 1 1 0 1 1 1 0 zf-RING of BARD1-type protein zf-piccolo PF05715.8 EGC38094.1 - 2.4 8.2 11.6 2.4 8.2 3.7 2.1 1 1 1 2 2 2 0 Piccolo Zn-finger zf-Nse PF11789.3 EGC38094.1 - 7 6.2 9.5 16 5.1 6.6 1.6 1 1 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit FNIP PF05725.7 EGC38095.1 - 2e-23 82.0 14.3 1.1e-11 44.4 0.1 5.6 2 2 2 5 5 5 4 FNIP Repeat LRR_5 PF13306.1 EGC38095.1 - 0.00096 18.8 0.2 0.0027 17.3 0.0 2.0 2 0 0 2 2 2 1 Leucine rich repeats (6 copies) CTP_transf_1 PF01148.15 EGC38097.1 - 1.2e-05 25.1 31.9 1.2e-05 25.1 22.1 4.6 1 1 1 3 3 3 1 Cytidylyltransferase family FNIP PF05725.7 EGC38099.1 - 8.4e-126 409.7 77.7 1e-14 54.1 0.7 11.4 5 3 8 14 14 14 14 FNIP Repeat LRR_5 PF13306.1 EGC38099.1 - 3.9e-09 36.2 3.9 0.17 11.6 0.7 4.4 3 1 1 4 4 4 3 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC38099.1 - 0.0078 16.1 15.8 2.1 8.3 0.0 7.6 5 2 3 8 8 8 1 Protein of unknown function (DUF1769) MbeB_N PF04837.7 EGC38099.1 - 0.034 14.2 0.3 38 4.4 0.0 4.0 4 0 0 4 4 4 0 MbeB-like, N-term conserved region FNIP PF05725.7 EGC38100.1 - 1.8e-69 229.4 18.6 3.9e-15 55.5 0.0 7.8 5 2 3 8 8 8 8 FNIP Repeat Endotoxin_N PF03945.9 EGC38101.1 - 1.4e-08 34.4 0.1 2.5e-08 33.5 0.0 1.4 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain LNS2 PF08235.8 EGC38101.1 - 0.045 13.3 0.1 0.1 12.1 0.1 1.6 1 0 0 1 1 1 0 LNS2 (Lipin/Ned1/Smp2) ABC_membrane PF00664.18 EGC38102.1 - 3.3e-112 374.4 21.7 1.3e-56 191.9 2.8 2.2 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC38102.1 - 4.9e-71 237.4 0.1 2.1e-34 118.7 0.1 2.5 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC38102.1 - 9.2e-14 51.1 0.0 3e-06 26.6 0.0 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGC38102.1 - 1.1e-09 37.3 3.8 0.00013 20.7 0.1 2.4 3 0 0 3 3 3 2 Predicted ATPase of the ABC class AAA_21 PF13304.1 EGC38102.1 - 4.3e-09 36.7 1.1 0.027 14.4 0.1 4.7 2 2 0 2 2 2 2 AAA domain AAA_29 PF13555.1 EGC38102.1 - 2.1e-06 27.1 1.1 0.023 14.1 0.1 2.6 2 0 0 2 2 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGC38102.1 - 2e-05 23.8 0.0 0.13 11.4 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGC38102.1 - 2.9e-05 23.9 2.7 0.22 11.4 0.1 3.6 2 2 0 2 2 2 2 Putative exonuclease SbcCD, C subunit AAA_22 PF13401.1 EGC38102.1 - 5.7e-05 23.2 1.2 0.34 11.0 0.1 3.3 2 2 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC38102.1 - 0.00041 20.3 2.6 0.22 11.5 0.0 3.3 2 2 1 3 3 3 2 AAA ATPase domain Miro PF08477.8 EGC38102.1 - 0.0087 16.5 0.0 10 6.6 0.0 3.3 3 0 0 3 3 3 0 Miro-like protein AAA_18 PF13238.1 EGC38102.1 - 0.01 16.1 3.7 2.9 8.2 0.0 3.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC38102.1 - 0.014 16.1 0.3 3.6 8.4 0.0 3.2 3 0 0 3 3 3 0 AAA domain Zeta_toxin PF06414.7 EGC38102.1 - 0.023 13.8 0.3 3 6.9 0.0 3.2 4 0 0 4 4 4 0 Zeta toxin Phage_T4_Ndd PF06591.6 EGC38102.1 - 0.091 12.3 0.0 11 5.5 0.0 2.4 2 0 0 2 2 2 0 T4-like phage nuclear disruption protein (Ndd) AAA_5 PF07728.9 EGC38102.1 - 0.13 11.9 1.4 18 5.0 0.0 3.9 4 1 0 4 4 4 0 AAA domain (dynein-related subfamily) UPF0081 PF03652.10 EGC38102.1 - 0.38 10.8 5.5 0.15 12.2 0.1 2.7 2 1 1 3 3 2 0 Uncharacterised protein family (UPF0081) IstB_IS21 PF01695.12 EGC38102.1 - 0.8 9.1 3.7 40 3.5 0.0 3.4 4 0 0 4 4 3 0 IstB-like ATP binding protein DUF3987 PF13148.1 EGC38102.1 - 2.4 6.6 6.5 46 2.4 0.0 3.2 3 0 0 3 3 3 0 Protein of unknown function (DUF3987) DUF3487 PF11990.3 EGC38102.1 - 6.9 6.0 14.5 0.048 13.0 1.6 3.0 3 0 0 3 3 2 0 Protein of unknown function (DUF3487) TFIIA_gamma_C PF02751.9 EGC38103.1 - 2.7e-24 84.7 3.5 3.7e-24 84.2 2.4 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit TFIIA_gamma_N PF02268.11 EGC38103.1 - 9e-23 79.6 0.9 1.2e-22 79.2 0.6 1.2 1 0 0 1 1 1 1 Transcription initiation factor IIA, gamma subunit, helical domain DUF4427 PF14468.1 EGC38103.1 - 0.054 13.2 0.1 0.074 12.7 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF4427) Dopey_N PF04118.9 EGC38103.1 - 0.058 12.1 0.0 0.06 12.1 0.0 1.1 1 0 0 1 1 1 0 Dopey, N-terminal eIF_4EBP PF05456.6 EGC38104.1 - 0.043 13.5 1.0 0.049 13.3 0.7 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) His_Phos_1 PF00300.17 EGC38105.1 - 1.3e-46 158.5 0.0 1.8e-46 158.0 0.0 1.2 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) FAD_binding_3 PF01494.14 EGC38106.1 - 8.3e-14 51.3 0.0 3.6e-10 39.4 0.0 2.1 2 0 0 2 2 2 2 FAD binding domain SE PF08491.5 EGC38106.1 - 0.0027 16.5 0.0 0.02 13.7 0.0 2.3 3 0 0 3 3 3 1 Squalene epoxidase Ras PF00071.17 EGC38107.1 - 1.4e-41 141.5 0.0 1.8e-41 141.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38107.1 - 1.2e-14 54.8 0.0 2.3e-14 53.9 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38107.1 - 6.8e-08 31.9 0.0 1.1e-07 31.2 0.0 1.4 1 1 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC38107.1 - 0.01 15.0 0.0 0.28 10.3 0.0 2.1 2 0 0 2 2 2 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGC38107.1 - 0.025 14.0 0.0 1.2 8.6 0.0 2.2 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGC38107.1 - 0.031 14.4 0.0 0.13 12.4 0.0 2.0 1 1 1 2 2 2 0 AAA domain NACHT PF05729.7 EGC38107.1 - 0.048 13.3 0.0 0.16 11.5 0.0 1.8 2 0 0 2 2 2 0 NACHT domain MobB PF03205.9 EGC38107.1 - 0.051 13.2 0.1 0.12 12.0 0.0 1.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_28 PF13521.1 EGC38107.1 - 0.061 13.2 0.0 0.095 12.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGC38108.1 - 4.8e-07 29.5 17.8 2.1e-06 27.5 12.4 2.2 1 1 0 1 1 1 1 AAA domain AAA_30 PF13604.1 EGC38108.1 - 0.00052 19.6 0.0 0.00092 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_19 PF13245.1 EGC38108.1 - 0.0022 17.7 0.1 0.0042 16.8 0.1 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_5 PF07728.9 EGC38108.1 - 0.028 14.1 0.0 0.077 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) HARP PF07443.8 EGC38108.1 - 0.029 13.7 1.6 0.047 13.0 0.2 2.1 2 0 0 2 2 2 0 HepA-related protein (HARP) AAA PF00004.24 EGC38108.1 - 0.035 14.3 0.1 0.32 11.1 0.0 2.7 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_25 PF13481.1 EGC38108.1 - 0.34 10.2 0.1 3.7 6.8 0.0 2.5 3 0 0 3 3 3 0 AAA domain Mem_trans PF03547.13 EGC38109.1 - 0.13 10.5 3.0 0.13 10.5 2.1 1.2 1 0 0 1 1 1 0 Membrane transport protein LMBR1 PF04791.11 EGC38109.1 - 0.95 7.9 4.8 1 7.8 3.3 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein Utp14 PF04615.8 EGC38109.1 - 4.7 5.2 29.9 5.9 4.9 20.7 1.0 1 0 0 1 1 1 0 Utp14 protein Raftlin PF15250.1 EGC38109.1 - 4.9 5.5 15.5 7.6 4.9 10.4 1.5 2 0 0 2 2 2 0 Raftlin SprA-related PF12118.3 EGC38109.1 - 9.4 5.4 23.4 13 5.0 16.2 1.1 1 0 0 1 1 1 0 SprA-related family Ndc1_Nup PF09531.5 EGC38109.1 - 9.8 4.4 16.3 12 4.1 11.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF2130 PF09903.4 EGC38111.1 - 0.008 14.9 0.6 0.013 14.2 0.4 1.4 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2130) DUF2013 PF09431.5 EGC38111.1 - 0.053 13.2 0.1 0.053 13.2 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2013) NUDIX PF00293.23 EGC38112.1 - 1.3e-10 41.0 0.0 1.9e-10 40.4 0.0 1.2 1 0 0 1 1 1 1 NUDIX domain Erf4 PF10256.4 EGC38113.1 - 1.3e-05 25.0 1.0 1.3e-05 25.0 0.7 2.0 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Spore_III_AE PF09546.5 EGC38113.1 - 0.0052 15.7 1.0 0.0071 15.3 0.7 1.1 1 0 0 1 1 1 1 Stage III sporulation protein AE (spore_III_AE) Homeobox_KN PF05920.6 EGC38115.1 - 4.1e-08 32.8 0.3 1.1e-07 31.3 0.2 1.9 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGC38115.1 - 4e-07 29.5 3.1 1.1e-06 28.1 2.1 1.8 1 0 0 1 1 1 1 Homeobox domain MFMR PF07777.6 EGC38115.1 - 0.00015 21.7 0.9 0.00015 21.7 0.6 3.1 3 0 0 3 3 3 1 G-box binding protein MFMR Fe_bilin_red PF05996.7 EGC38116.1 - 0.034 13.6 2.8 0.043 13.2 1.9 1.1 1 0 0 1 1 1 0 Ferredoxin-dependent bilin reductase DUF3893 PF13032.1 EGC38116.1 - 0.67 10.0 6.5 0.58 10.2 3.2 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF3893) Pex26 PF07163.7 EGC38116.1 - 6.1 5.6 5.5 1.2 8.0 0.2 2.0 1 1 1 2 2 2 0 Pex26 protein G-7-MTase PF12803.2 EGC38116.1 - 7.2 5.6 11.7 0.18 10.9 2.3 1.8 1 1 1 2 2 2 0 mRNA (guanine-7-)methyltransferase (G-7-MTase) AMP-binding PF00501.23 EGC38117.1 - 2.9e-71 240.0 0.0 3.6e-71 239.7 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC38117.1 - 4.3e-05 24.3 0.0 8.4e-05 23.4 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Brix PF04427.13 EGC38118.1 - 7.6e-40 136.6 0.5 1.2e-39 135.9 0.3 1.3 1 0 0 1 1 1 1 Brix domain SLX9 PF15341.1 EGC38118.1 - 0.016 15.6 3.0 0.026 14.9 2.1 1.3 1 0 0 1 1 1 0 Ribosome biogenesis protein SLX9 DUF1294 PF06961.8 EGC38119.1 - 8.4e-19 67.2 1.0 8.4e-19 67.2 0.7 1.6 2 0 0 2 2 2 1 Protein of unknown function (DUF1294) NADH-u_ox-rdase PF10785.4 EGC38119.1 - 0.086 13.0 0.4 0.27 11.5 0.2 1.8 1 1 1 2 2 2 0 NADH-ubiquinone oxidoreductase complex I, 21 kDa subunit SID-1_RNA_chan PF13965.1 EGC38119.1 - 0.14 10.2 1.0 0.23 9.6 0.1 1.6 2 0 0 2 2 2 0 dsRNA-gated channel SID-1 DUF3169 PF11368.3 EGC38119.1 - 1.3 8.2 6.0 0.88 8.7 0.1 2.3 1 1 2 3 3 3 0 Protein of unknown function (DUF3169) DUF2762 PF10960.3 EGC38119.1 - 9.2 6.0 8.8 19 5.0 4.7 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF2762) AMP-binding PF00501.23 EGC38121.1 - 0.054 11.8 0.0 0.097 11.0 0.0 1.4 1 0 0 1 1 1 0 AMP-binding enzyme Peptidase_M28 PF04389.12 EGC38122.1 - 8e-17 61.5 0.0 1.2e-16 60.9 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M28 Peptidase_M20 PF01546.23 EGC38122.1 - 6.3e-07 29.0 0.9 1e-06 28.3 0.1 1.7 1 1 1 2 2 2 1 Peptidase family M20/M25/M40 DUF3671 PF12420.3 EGC38122.1 - 0.041 13.8 0.5 0.088 12.7 0.4 1.5 1 0 0 1 1 1 0 Protein of unknown function Membrane_bind PF14564.1 EGC38123.1 - 1.3e-36 125.1 0.0 2e-36 124.5 0.0 1.3 1 0 0 1 1 1 1 Membrane binding Crystall_3 PF08964.5 EGC38123.1 - 1e-32 111.6 0.1 1.6e-32 111.0 0.0 1.3 1 0 0 1 1 1 1 Beta/Gamma crystallin PagP PF07017.6 EGC38123.1 - 0.015 14.5 0.0 0.026 13.8 0.0 1.4 1 0 0 1 1 1 0 Antimicrobial peptide resistance and lipid A acylation protein PagP VPS9 PF02204.13 EGC38124.1 - 1.6e-23 82.6 2.2 5.7e-23 80.9 1.6 2.0 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain SKG6 PF08693.5 EGC38125.1 - 0.018 14.3 0.6 0.037 13.3 0.4 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3042 PF11240.3 EGC38125.1 - 0.11 12.3 1.1 0.26 11.0 0.7 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF3042) BUD22 PF09073.5 EGC38127.1 - 0.084 11.9 5.4 0.15 11.1 3.7 1.3 1 0 0 1 1 1 0 BUD22 E1-E2_ATPase PF00122.15 EGC38128.1 - 4.2e-17 61.9 0.0 4.2e-17 61.9 0.0 2.1 2 0 0 2 2 2 1 E1-E2 ATPase HAD PF12710.2 EGC38128.1 - 6.9e-17 62.2 0.0 1.4e-16 61.2 0.0 1.6 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC38128.1 - 1.4e-14 55.0 0.0 2.3e-13 51.0 0.0 2.7 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC38128.1 - 9.1e-10 38.3 0.3 5e-09 35.9 0.0 2.5 3 0 0 3 3 3 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Hydrolase_3 PF08282.7 EGC38128.1 - 0.0004 20.0 2.0 0.0061 16.1 0.0 3.2 3 0 0 3 3 3 1 haloacid dehalogenase-like hydrolase Dynein_heavy PF03028.10 EGC38132.1 - 5.1e-224 745.4 2.2 1.1e-223 744.3 1.5 1.6 1 0 0 1 1 1 1 Dynein heavy chain and region D6 of dynein motor DHC_N1 PF08385.7 EGC38132.1 - 2.6e-167 557.7 14.7 2.6e-167 557.7 10.2 5.6 6 0 0 6 6 6 2 Dynein heavy chain, N-terminal region 1 DHC_N2 PF08393.8 EGC38132.1 - 7.6e-121 403.4 11.9 7.6e-121 403.4 8.2 6.1 7 1 0 8 8 8 1 Dynein heavy chain, N-terminal region 2 AAA_6 PF12774.2 EGC38132.1 - 1.1e-83 280.3 0.1 3.6e-83 278.6 0.0 1.9 2 0 0 2 2 2 1 Hydrolytic ATP binding site of dynein motor region D1 AAA_9 PF12781.2 EGC38132.1 - 1.5e-47 161.3 4.5 2.5e-46 157.3 0.0 3.7 3 0 0 3 3 3 1 ATP-binding dynein motor region D5 AAA_8 PF12780.2 EGC38132.1 - 2.7e-43 147.9 0.0 4.6e-41 140.5 0.0 2.8 1 1 0 1 1 1 1 P-loop containing dynein motor region D4 MT PF12777.2 EGC38132.1 - 2.9e-41 141.3 14.1 6.9e-41 140.1 9.8 1.7 1 0 0 1 1 1 1 Microtubule-binding stalk of dynein motor AAA_5 PF07728.9 EGC38132.1 - 7.7e-36 122.8 0.1 6.5e-14 51.8 0.0 6.5 6 1 0 6 6 5 4 AAA domain (dynein-related subfamily) AAA_7 PF12775.2 EGC38132.1 - 9e-25 87.2 0.1 2.9e-23 82.3 0.0 3.0 4 0 0 4 4 4 1 P-loop containing dynein motor region D3 AAA_22 PF13401.1 EGC38132.1 - 6e-15 55.5 0.0 0.0011 19.1 0.0 6.5 4 1 0 5 5 5 4 AAA domain AAA PF00004.24 EGC38132.1 - 9.2e-12 45.3 0.0 0.021 14.9 0.0 5.5 5 0 0 5 5 4 3 ATPase family associated with various cellular activities (AAA) AAA_33 PF13671.1 EGC38132.1 - 5.1e-08 32.9 0.0 0.39 10.5 0.0 5.0 4 0 0 4 4 4 2 AAA domain AAA_19 PF13245.1 EGC38132.1 - 1e-05 25.1 0.1 0.38 10.5 0.0 3.7 3 0 0 3 3 3 1 Part of AAA domain AAA_17 PF13207.1 EGC38132.1 - 4.9e-05 24.1 1.4 2.9 8.7 0.0 5.9 5 0 0 5 5 4 1 AAA domain AAA_30 PF13604.1 EGC38132.1 - 9.2e-05 22.0 0.0 3.5 7.1 0.0 4.0 3 0 0 3 3 3 1 AAA domain Zeta_toxin PF06414.7 EGC38132.1 - 0.00026 20.1 0.0 0.25 10.4 0.0 3.5 3 0 0 3 3 3 1 Zeta toxin IstB_IS21 PF01695.12 EGC38132.1 - 0.0018 17.6 3.4 0.33 10.3 0.0 4.2 5 0 0 5 5 4 1 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGC38132.1 - 0.0073 15.4 3.3 0.87 8.6 0.0 4.0 5 0 0 5 5 5 1 Magnesium chelatase, subunit ChlI AAA_25 PF13481.1 EGC38132.1 - 0.095 12.0 0.2 0.58 9.5 0.0 2.5 3 0 0 3 3 2 0 AAA domain TMEM154 PF15102.1 EGC38136.1 - 3.8e-05 23.4 0.9 9.2e-05 22.1 0.6 1.6 1 0 0 1 1 1 1 TMEM154 protein family DUF3377 PF11857.3 EGC38136.1 - 0.04 13.5 0.4 0.11 12.1 0.3 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) DUF4519 PF15012.1 EGC38136.1 - 0.14 12.1 4.6 0.14 12.1 2.4 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF4519) TMEM154 PF15102.1 EGC38137.1 - 0.0072 16.0 0.4 0.0072 16.0 0.3 2.2 2 0 0 2 2 2 1 TMEM154 protein family LRR19-TM PF15176.1 EGC38137.1 - 0.017 14.7 0.4 0.055 13.1 0.0 2.0 2 0 0 2 2 2 0 Leucine-rich repeat family 19 TM domain Methyltransf_12 PF08242.7 EGC38137.1 - 3.6 8.1 9.2 3.9 8.0 2.2 3.0 2 1 1 3 3 3 0 Methyltransferase domain WD40 PF00400.27 EGC38139.1 - 2.8e-49 163.3 22.4 7.7e-09 35.1 0.1 7.7 7 0 0 7 7 7 7 WD domain, G-beta repeat Rootletin PF15035.1 EGC38139.1 - 8e-06 25.9 1.0 1.2e-05 25.3 0.7 1.2 1 0 0 1 1 1 1 Ciliary rootlet component, centrosome cohesion zf-C3HC4_4 PF15227.1 EGC38139.1 - 0.00019 21.2 1.5 0.00019 21.2 1.0 2.9 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING PQQ_3 PF13570.1 EGC38139.1 - 0.00028 21.0 10.2 1.7 9.0 0.0 6.3 6 1 1 7 7 6 1 PQQ-like domain zf-TRAF PF02176.13 EGC38139.1 - 0.00083 19.6 9.8 0.0023 18.2 6.8 1.9 1 0 0 1 1 1 1 TRAF-type zinc finger Sina PF03145.11 EGC38139.1 - 0.0013 18.4 9.9 0.015 14.9 0.5 2.5 1 1 1 2 2 2 1 Seven in absentia protein family zf-C3HC4 PF00097.20 EGC38139.1 - 0.0014 18.2 1.4 0.0014 18.2 1.0 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38139.1 - 0.0025 17.8 1.6 0.0025 17.8 1.1 2.6 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) SecIII_SopE_N PF05364.9 EGC38139.1 - 0.0051 16.6 0.1 0.012 15.4 0.1 1.6 1 0 0 1 1 1 1 Salmonella type III secretion SopE effector N-terminus UBN2 PF14223.1 EGC38139.1 - 0.0066 16.2 0.7 0.013 15.3 0.5 1.4 1 0 0 1 1 1 1 gag-polypeptide of LTR copia-type zf-RING_5 PF14634.1 EGC38139.1 - 0.0087 15.7 1.3 0.0087 15.7 0.9 2.7 2 0 0 2 2 2 1 zinc-RING finger domain zf-Nse PF11789.3 EGC38139.1 - 0.0094 15.4 0.1 0.0094 15.4 0.1 2.4 3 0 0 3 3 2 1 Zinc-finger of the MIZ type in Nse subunit Nup160 PF11715.3 EGC38139.1 - 0.028 12.5 13.1 0.76 7.8 0.1 4.4 3 1 0 4 4 4 0 Nucleoporin Nup120/160 EzrA PF06160.7 EGC38139.1 - 0.066 11.3 3.1 0.094 10.8 2.2 1.1 1 0 0 1 1 1 0 Septation ring formation regulator, EzrA CCDC144C PF14915.1 EGC38139.1 - 0.073 11.9 5.1 0.11 11.4 3.6 1.2 1 0 0 1 1 1 0 CCDC144C protein coiled-coil region Syntaxin PF00804.20 EGC38139.1 - 0.074 13.2 4.2 0.25 11.5 2.9 1.9 1 0 0 1 1 1 0 Syntaxin zf-RING_2 PF13639.1 EGC38139.1 - 0.088 12.6 0.3 0.088 12.6 0.2 3.1 2 0 0 2 2 2 0 Ring finger domain DUF1378 PF07125.6 EGC38139.1 - 0.61 10.0 3.0 16 5.4 0.1 3.0 3 0 0 3 3 3 0 Protein of unknown function (DUF1378) TFIIIC_sub6 PF10419.4 EGC38139.1 - 6.2 6.3 5.6 2.1e+02 1.4 0.0 4.5 5 0 0 5 5 5 0 TFIIIC subunit MSP1_C PF07462.6 EGC38140.1 - 0.27 9.5 1.5 0.32 9.3 1.1 1.0 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus KAR9 PF08580.5 EGC38140.1 - 0.38 8.9 5.6 0.42 8.8 3.9 1.0 1 0 0 1 1 1 0 Yeast cortical protein KAR9 Phosphoprotein PF00922.12 EGC38140.1 - 2.2 7.4 6.7 2.6 7.1 4.6 1.0 1 0 0 1 1 1 0 Vesiculovirus phosphoprotein 3Beta_HSD PF01073.14 EGC38141.1 - 2.1e-32 111.9 0.0 2.7e-32 111.6 0.0 1.1 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC38141.1 - 2.3e-25 89.4 0.0 3.1e-25 89.0 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family NAD_binding_4 PF07993.7 EGC38141.1 - 3.6e-19 68.6 0.0 9.7e-11 41.0 0.0 2.2 1 1 1 2 2 2 2 Male sterility protein NAD_binding_10 PF13460.1 EGC38141.1 - 5e-15 55.9 0.0 6.6e-15 55.5 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NmrA PF05368.8 EGC38141.1 - 4.4e-12 45.7 0.0 6.1e-12 45.2 0.0 1.2 1 0 0 1 1 1 1 NmrA-like family RmlD_sub_bind PF04321.12 EGC38141.1 - 8.2e-11 41.3 0.0 1.3e-10 40.6 0.0 1.5 1 1 0 1 1 1 1 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC38141.1 - 1.5e-06 27.3 0.0 7.2e-06 25.1 0.0 1.9 3 0 0 3 3 3 1 Polysaccharide biosynthesis protein adh_short PF00106.20 EGC38141.1 - 3.2e-05 23.9 0.0 5.3e-05 23.1 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Saccharop_dh PF03435.13 EGC38141.1 - 0.00031 19.8 0.0 0.00043 19.3 0.0 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase KR PF08659.5 EGC38141.1 - 0.0008 19.1 0.0 0.0016 18.1 0.0 1.4 1 1 0 1 1 1 1 KR domain TrkA_N PF02254.13 EGC38141.1 - 0.0011 18.9 0.0 0.0017 18.3 0.0 1.2 1 0 0 1 1 1 1 TrkA-N domain ELFV_dehydrog PF00208.16 EGC38141.1 - 0.01 15.4 0.8 0.099 12.2 0.2 2.5 1 1 1 2 2 2 0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase F420_oxidored PF03807.12 EGC38141.1 - 0.011 16.1 0.0 0.02 15.2 0.0 1.4 1 0 0 1 1 1 0 NADP oxidoreductase coenzyme F420-dependent DapB_N PF01113.15 EGC38141.1 - 0.015 15.2 0.0 0.024 14.5 0.0 1.3 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus NAD_binding_2 PF03446.10 EGC38141.1 - 0.059 13.2 0.0 0.097 12.5 0.0 1.4 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase PH PF00169.24 EGC38142.1 - 1.7e-22 79.5 1.0 7.7e-14 51.7 0.1 3.1 2 0 0 2 2 2 2 PH domain TPR_11 PF13414.1 EGC38142.1 - 1.4e-17 63.1 3.6 1.4e-07 31.0 0.1 3.1 3 0 0 3 3 3 2 TPR repeat TPR_19 PF14559.1 EGC38142.1 - 3.9e-11 43.1 0.4 1.6e-06 28.3 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC38142.1 - 5.1e-08 32.2 2.5 0.025 14.4 0.1 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat PH_3 PF14593.1 EGC38142.1 - 5.7e-08 32.5 2.4 2.2e-05 24.2 0.1 3.6 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC38142.1 - 4.7e-07 30.0 0.3 0.00016 21.8 0.0 3.4 2 1 0 2 2 2 1 Pleckstrin homology domain C2 PF00168.25 EGC38142.1 - 1.4e-05 24.8 0.0 4.9e-05 23.0 0.0 2.0 1 0 0 1 1 1 1 C2 domain TPR_1 PF00515.23 EGC38142.1 - 1.4e-05 24.4 8.4 0.023 14.2 0.3 4.5 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38142.1 - 0.00016 22.2 0.2 0.0043 17.6 0.0 2.3 2 0 0 2 2 2 1 Tetratricopeptide repeat PH_9 PF15410.1 EGC38142.1 - 0.00076 19.6 0.3 0.0034 17.5 0.0 2.2 2 0 0 2 2 2 1 Pleckstrin homology domain TPR_14 PF13428.1 EGC38142.1 - 0.012 16.1 0.0 10 7.0 0.0 3.3 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38142.1 - 0.11 12.3 5.9 3.4 7.6 0.0 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC38142.1 - 0.46 10.4 3.0 2.2 8.2 0.0 3.1 4 1 0 4 4 3 0 Tetratricopeptide repeat DUF1625 PF07787.7 EGC38143.1 - 0.0026 17.0 0.0 0.0041 16.4 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1625) PQQ_3 PF13570.1 EGC38143.1 - 0.21 11.9 1.6 15 6.0 0.0 4.0 4 0 0 4 4 4 0 PQQ-like domain SBBP PF06739.6 EGC38143.1 - 3 7.7 12.6 0.22 11.3 2.0 3.1 3 0 0 3 3 3 0 Beta-propeller repeat ABM PF03992.11 EGC38144.1 - 3.8e-14 52.4 0.0 4.3e-14 52.2 0.0 1.1 1 0 0 1 1 1 1 Antibiotic biosynthesis monooxygenase DUF3294 PF07957.6 EGC38144.1 - 0.032 13.7 0.3 0.037 13.5 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3294) DUF4188 PF13826.1 EGC38144.1 - 0.052 13.6 0.1 0.07 13.2 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4188) DUF2661 PF10860.3 EGC38144.1 - 0.1 12.7 2.3 0.11 12.6 1.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2661) Acetyltransf_7 PF13508.1 EGC38145.1 - 1.6e-11 44.2 0.1 2.4e-11 43.6 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC38145.1 - 1.9e-07 31.0 0.0 4.3e-07 29.8 0.0 1.6 1 1 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_5 PF13444.1 EGC38145.1 - 1.7e-06 28.5 0.0 6.2e-05 23.5 0.0 2.5 2 1 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC38145.1 - 1.9e-06 27.9 0.0 2.5e-06 27.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC38145.1 - 0.00092 19.3 0.0 0.0011 19.1 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain FR47 PF08445.5 EGC38145.1 - 0.00098 18.8 0.0 0.0023 17.6 0.0 1.6 1 0 0 1 1 1 1 FR47-like protein Autoind_synth PF00765.12 EGC38145.1 - 0.0016 17.7 0.0 0.0025 17.1 0.0 1.3 1 0 0 1 1 1 1 Autoinducer synthetase Acetyltransf_CG PF14542.1 EGC38145.1 - 0.063 13.1 0.0 0.11 12.3 0.0 1.4 1 0 0 1 1 1 0 GCN5-related N-acetyl-transferase TPR_11 PF13414.1 EGC38146.1 - 2.3e-18 65.5 14.8 4.8e-09 35.7 0.6 3.2 2 1 2 4 4 4 3 TPR repeat TPR_1 PF00515.23 EGC38146.1 - 7.1e-11 41.2 8.9 3.8e-06 26.2 0.2 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC38146.1 - 2.4e-09 36.3 9.4 2e-05 24.1 0.2 4.3 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38146.1 - 4.1e-06 27.0 0.3 9.9e-06 25.8 0.2 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38146.1 - 6.1e-06 26.3 2.6 0.37 11.3 0.0 4.4 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38146.1 - 1.2e-05 24.6 4.6 0.036 13.8 0.1 4.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38146.1 - 2.9e-05 24.6 0.2 0.00019 22.0 0.0 2.4 2 1 0 2 2 2 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC38146.1 - 3.9e-05 23.7 4.0 0.0058 16.7 0.6 3.4 2 1 2 4 4 4 3 Anaphase-promoting complex, cyclosome, subunit 3 TPR_17 PF13431.1 EGC38146.1 - 0.00055 19.9 1.6 0.11 12.7 0.0 4.1 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC38146.1 - 0.0011 18.8 4.1 0.0013 18.6 0.2 3.0 2 1 1 3 3 3 2 Tetratricopeptide repeat TPR_9 PF13371.1 EGC38146.1 - 0.0029 17.4 0.0 0.0072 16.1 0.0 1.7 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC38146.1 - 0.0048 16.7 0.0 0.025 14.4 0.0 2.2 2 0 0 2 2 2 1 Fis1 C-terminal tetratricopeptide repeat Coatomer_E PF04733.9 EGC38146.1 - 0.0076 15.4 1.5 0.016 14.3 0.1 2.3 2 1 0 2 2 2 1 Coatomer epsilon subunit TPR_14 PF13428.1 EGC38146.1 - 0.016 15.7 0.0 2 9.2 0.1 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat Pep3_Vps18 PF05131.9 EGC38146.1 - 0.047 13.1 0.0 0.14 11.5 0.0 1.8 1 0 0 1 1 1 0 Pep3/Vps18/deep orange family Alkyl_sulf_dimr PF14863.1 EGC38146.1 - 0.13 12.4 1.0 18 5.5 0.0 3.0 3 1 1 4 4 3 0 Alkyl sulfatase dimerisation RinB PF06116.7 EGC38149.1 - 0.25 10.9 4.1 0.18 11.4 0.1 2.8 2 0 0 2 2 2 0 Transcriptional activator RinB tRNA-synt_2c PF01411.14 EGC38151.1 - 3.9e-209 695.5 0.0 5.6e-209 694.9 0.0 1.2 1 0 0 1 1 1 1 tRNA synthetases class II (A) tRNA_SAD PF07973.9 EGC38151.1 - 1.1e-15 57.1 0.0 3.1e-15 55.7 0.0 1.8 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain DHHA1 PF02272.14 EGC38151.1 - 5.6e-10 38.7 0.3 1.3e-09 37.5 0.2 1.7 1 0 0 1 1 1 1 DHHA1 domain zf-RING_2 PF13639.1 EGC38152.1 - 7.9e-10 38.4 8.8 1.7e-09 37.3 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38152.1 - 7.4e-09 35.1 7.1 1.4e-08 34.2 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38152.1 - 3.4e-07 29.7 11.2 1e-06 28.2 7.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38152.1 - 2.6e-06 27.3 10.4 5.8e-06 26.2 7.2 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38152.1 - 2.7e-05 23.8 8.2 2.7e-05 23.8 5.7 1.8 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC38152.1 - 0.00036 20.0 9.8 0.00084 18.8 6.8 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGC38152.1 - 0.0013 18.8 7.2 0.0034 17.4 5.0 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC38152.1 - 0.0045 16.8 7.1 0.014 15.2 4.9 1.9 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING CAF-1_p150 PF11600.3 EGC38152.1 - 0.0059 16.0 69.2 0.0059 16.0 48.0 3.1 2 1 1 3 3 2 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_UBOX PF13445.1 EGC38152.1 - 0.037 13.7 6.9 0.17 11.6 4.8 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGC38152.1 - 0.058 13.1 2.4 0.12 12.1 1.7 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-MIZ PF02891.15 EGC38152.1 - 0.2 11.1 8.1 0.42 10.1 5.6 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Prok-RING_4 PF14447.1 EGC38152.1 - 0.69 9.4 7.3 2.3 7.8 5.1 1.9 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF4583 PF15190.1 EGC38153.1 - 0.07 12.7 2.2 0.074 12.6 0.5 1.8 1 1 0 1 1 1 0 Domain of unknown function (DUF4583) CCSMST1 PF15013.1 EGC38153.1 - 0.13 12.2 0.2 0.13 12.2 0.1 2.9 2 1 1 3 3 3 0 CCSMST1 family Reticulon PF02453.12 EGC38153.1 - 8.3 5.9 6.5 1.7 8.2 1.2 2.1 1 1 1 2 2 2 0 Reticulon EGF_2 PF07974.8 EGC38154.1 - 6.9e-05 22.9 7.5 6.9e-05 22.9 5.2 1.6 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.19 EGC38154.1 - 0.0031 17.4 7.7 0.0072 16.2 5.4 1.6 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EGC38154.1 - 0.13 12.2 5.1 0.25 11.3 3.6 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain Pal1 PF08316.6 EGC38155.1 - 0.29 11.5 8.1 0.37 11.2 5.6 1.1 1 0 0 1 1 1 0 Pal1 cell morphology protein Acetyltransf_1 PF00583.19 EGC38157.1 - 4.7e-13 48.9 0.0 6.6e-13 48.5 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC38157.1 - 1.5e-09 37.8 0.1 2.1e-09 37.4 0.1 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_9 PF13527.1 EGC38157.1 - 0.12 12.1 0.0 0.16 11.8 0.0 1.2 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain GSIII_N PF12437.3 EGC38158.1 - 1.4e-71 239.2 0.0 2.7e-71 238.2 0.0 1.5 1 0 0 1 1 1 1 Glutamine synthetase type III N terminal Gln-synt_C PF00120.19 EGC38158.1 - 3.8e-42 144.2 0.0 5.4e-42 143.7 0.0 1.2 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain S6PP PF05116.8 EGC38158.1 - 0.12 11.7 0.1 0.23 10.7 0.1 1.4 1 0 0 1 1 1 0 Sucrose-6F-phosphate phosphohydrolase ATP1G1_PLM_MAT8 PF02038.11 EGC38159.1 - 0.51 9.3 3.3 1.5 7.9 2.3 1.7 1 0 0 1 1 1 0 ATP1G1/PLM/MAT8 family EGF_2 PF07974.8 EGC38159.1 - 3.1 8.0 10.2 5.6 7.2 7.1 1.4 1 0 0 1 1 1 0 EGF-like domain RhoGAP PF00620.22 EGC38160.1 - 2.8e-30 104.9 0.1 5.6e-30 103.9 0.1 1.5 1 0 0 1 1 1 1 RhoGAP domain Motile_Sperm PF00635.21 EGC38160.1 - 0.11 12.1 2.9 0.18 11.4 1.5 1.7 2 0 0 2 2 2 0 MSP (Major sperm protein) domain Maf1 PF09174.5 EGC38161.1 - 4.9e-67 225.2 3.6 5.8e-67 224.9 2.5 1.1 1 0 0 1 1 1 1 Maf1 regulator SPRY PF00622.23 EGC38162.1 - 6.9e-13 48.7 1.9 6.9e-13 48.7 1.3 1.6 2 0 0 2 2 2 1 SPRY domain F-box-like PF12937.2 EGC38162.1 - 4.4e-06 26.3 0.0 8.1e-06 25.4 0.0 1.5 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC38162.1 - 0.0035 16.9 0.1 0.0077 15.8 0.1 1.5 1 0 0 1 1 1 1 F-box domain LRR_4 PF12799.2 EGC38164.1 - 2.1e-10 39.9 20.1 0.00023 20.7 1.0 6.0 2 2 1 4 4 4 4 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC38164.1 - 6.3e-10 38.6 19.7 2.5e-05 23.9 1.6 4.4 4 0 0 4 4 4 2 Leucine rich repeat LRR_1 PF00560.28 EGC38164.1 - 2.5e-05 23.7 14.8 4.4 7.7 0.2 7.4 5 1 1 6 6 6 3 Leucine Rich Repeat LRR_9 PF14580.1 EGC38164.1 - 0.0029 17.1 3.4 0.024 14.2 2.2 2.3 1 1 1 2 2 2 2 Leucine-rich repeat LRR_7 PF13504.1 EGC38164.1 - 0.0064 16.5 9.1 17 6.1 0.1 6.6 5 1 1 6 6 6 2 Leucine rich repeat LRR_6 PF13516.1 EGC38164.1 - 0.18 11.9 18.8 5.7 7.3 0.0 6.9 6 0 0 6 6 6 0 Leucine Rich repeat PRY PF13765.1 EGC38165.1 - 0.023 14.2 1.6 8.2 6.0 0.0 3.1 2 1 1 3 3 3 0 SPRY-associated domain PRY PF13765.1 EGC38166.1 - 0.018 14.5 0.3 4.2 6.9 0.0 2.6 3 0 0 3 3 3 0 SPRY-associated domain DDE_3 PF13358.1 EGC38167.1 - 4.7e-09 36.1 0.1 7.7e-09 35.4 0.1 1.3 1 0 0 1 1 1 1 DDE superfamily endonuclease GST_N_3 PF13417.1 EGC38168.1 - 2e-12 47.1 0.0 3e-12 46.5 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N_2 PF13409.1 EGC38168.1 - 8e-12 44.9 0.0 1.3e-11 44.3 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC38168.1 - 2.7e-10 40.2 0.0 6.4e-10 39.0 0.0 1.6 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Glutaredoxin PF00462.19 EGC38168.1 - 0.035 14.0 0.0 0.088 12.8 0.0 1.6 2 0 0 2 2 2 0 Glutaredoxin Met_gamma_lyase PF06838.6 EGC38170.1 - 0.04 12.2 0.1 0.045 12.0 0.1 1.1 1 0 0 1 1 1 0 Methionine gamma-lyase DUF3388 PF11868.3 EGC38170.1 - 0.26 10.4 4.2 0.23 10.5 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3388) AMP-binding PF00501.23 EGC38171.1 - 3.6e-83 279.2 0.0 4.8e-83 278.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC38171.1 - 8.2e-17 61.9 0.0 1.5e-16 61.0 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain AMP-binding PF00501.23 EGC38172.1 - 5.1e-81 272.1 0.0 6.5e-81 271.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC38172.1 - 1.6e-15 57.8 0.0 2.8e-15 57.0 0.0 1.4 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain PLDc_2 PF13091.1 EGC38173.1 - 1.8e-14 53.5 1.2 1e-08 34.9 0.1 3.4 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGC38173.1 - 2e-14 52.8 1.5 1.7e-06 27.6 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif EF-hand_8 PF13833.1 EGC38173.1 - 0.0023 17.4 0.6 0.019 14.5 0.1 2.9 2 1 0 2 2 2 1 EF-hand domain pair EF-hand_1 PF00036.27 EGC38173.1 - 0.008 15.4 0.0 0.055 12.7 0.0 2.6 1 0 0 1 1 1 1 EF hand EF-hand_7 PF13499.1 EGC38173.1 - 0.011 15.8 1.6 0.083 13.0 0.6 3.0 3 1 0 3 3 3 0 EF-hand domain pair DUF572 PF04502.8 EGC38174.1 - 3.9e-81 272.7 19.3 4.2e-81 272.6 13.4 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) E6 PF00518.12 EGC38174.1 - 0.048 14.0 4.9 0.82 10.0 0.7 3.0 1 1 2 3 3 3 0 Early Protein (E6) DNA_RNApol_7kD PF03604.8 EGC38174.1 - 0.055 12.9 1.2 5.5 6.5 0.0 2.5 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit Yippee-Mis18 PF03226.9 EGC38174.1 - 0.075 13.0 1.9 5.1 7.1 0.0 2.7 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly Zn_ribbon_recom PF13408.1 EGC38174.1 - 0.13 12.5 5.9 0.46 10.7 0.2 2.4 1 1 1 2 2 2 0 Recombinase zinc beta ribbon domain TF_Zn_Ribbon PF08271.7 EGC38174.1 - 0.14 11.4 0.4 0.14 11.4 0.3 2.6 3 0 0 3 3 3 0 TFIIB zinc-binding Vfa1 PF08432.5 EGC38174.1 - 0.32 11.0 14.3 0.45 10.5 9.9 1.3 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 RNA_pol_N PF01194.12 EGC38174.1 - 0.8 9.7 5.0 1.2 9.1 0.0 3.1 2 1 0 2 2 2 0 RNA polymerases N / 8 kDa subunit zinc_ribbon_4 PF13717.1 EGC38174.1 - 4.5 7.0 5.9 12 5.7 0.1 3.0 3 0 0 3 3 3 0 zinc-ribbon domain Yos1 PF08571.5 EGC38175.1 - 5.9e-12 45.5 0.5 7.2e-12 45.2 0.4 1.1 1 0 0 1 1 1 1 Yos1-like Ras PF00071.17 EGC38176.1 - 7.9e-29 100.1 0.0 1e-28 99.7 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38176.1 - 9.3e-17 61.6 0.2 4.2e-16 59.5 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC38176.1 - 1.3e-05 24.5 0.6 2e-05 23.9 0.4 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family HEAT PF02985.17 EGC38177.1 - 5.1e-50 163.0 23.1 0.001 18.9 0.0 23.3 27 0 0 27 27 27 10 HEAT repeat HEAT_2 PF13646.1 EGC38177.1 - 8.6e-49 163.7 5.9 2.4e-09 37.3 0.0 17.0 9 4 9 18 18 18 12 HEAT repeats DUF3554 PF12074.3 EGC38177.1 - 1.2e-37 130.1 20.8 1.2e-37 130.1 14.4 7.6 5 1 2 7 7 7 1 Domain of unknown function (DUF3554) HEAT_EZ PF13513.1 EGC38177.1 - 4.2e-35 119.3 11.7 0.0083 16.5 0.0 19.0 16 3 5 21 21 21 8 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC38177.1 - 5.7e-20 71.5 0.3 0.081 13.3 0.0 10.8 10 0 0 10 10 10 5 Vacuolar 14 Fab1-binding region CLASP_N PF12348.3 EGC38177.1 - 2.7e-16 59.6 12.8 8e-06 25.3 0.0 7.8 7 0 0 7 7 7 4 CLASP N terminal Arm PF00514.18 EGC38177.1 - 1.4e-05 24.7 12.6 0.22 11.4 0.0 7.8 8 0 0 8 8 8 2 Armadillo/beta-catenin-like repeat HEAT_PBS PF03130.11 EGC38177.1 - 5 7.8 13.5 35 5.2 0.0 7.4 10 0 0 10 10 10 0 PBS lyase HEAT-like repeat MGC-24 PF05283.6 EGC38178.1 - 1.8 8.2 8.1 2.5 7.8 5.6 1.2 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Neisseria_TspB PF05616.8 EGC38178.1 - 7.7 4.7 8.0 11 4.2 5.5 1.1 1 0 0 1 1 1 0 Neisseria meningitidis TspB protein p450 PF00067.17 EGC38179.1 - 5.2e-78 262.6 1.7 7.5e-78 262.0 1.2 1.1 1 0 0 1 1 1 1 Cytochrome P450 Arm PF00514.18 EGC38179.1 - 7.5e-11 41.4 3.6 0.00021 20.9 0.2 3.7 3 0 0 3 3 3 3 Armadillo/beta-catenin-like repeat HEAT_EZ PF13513.1 EGC38179.1 - 0.004 17.5 0.0 0.074 13.5 0.0 2.5 2 0 0 2 2 2 1 HEAT-like repeat HEAT_2 PF13646.1 EGC38179.1 - 0.023 14.9 0.0 0.22 11.7 0.0 2.3 1 1 1 2 2 2 0 HEAT repeats SR-25 PF10500.4 EGC38180.1 - 0.067 12.6 4.1 0.07 12.5 2.8 1.1 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Vasculin PF15337.1 EGC38180.1 - 0.099 13.1 2.2 0.12 12.8 1.5 1.2 1 0 0 1 1 1 0 Vascular protein family Vasculin-like 1 USP8_dimer PF08969.6 EGC38180.1 - 0.099 12.6 6.9 0.18 11.7 4.7 1.6 1 1 0 1 1 1 0 USP8 dimerisation domain DUF4446 PF14584.1 EGC38181.1 - 0.07 12.9 12.3 0.41 10.4 3.3 2.4 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Dzip-like_N PF13815.1 EGC38181.1 - 1.6 8.5 17.8 0.064 13.0 7.4 1.9 2 0 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal Telomerase_RBD PF12009.3 EGC38181.1 - 1.8 8.4 7.8 0.43 10.4 0.8 2.5 1 1 0 2 2 2 0 Telomerase ribonucleoprotein complex - RNA binding domain DUF106 PF01956.11 EGC38181.1 - 7.2 6.1 17.1 0.03 13.8 2.9 2.5 1 1 1 2 2 2 0 Integral membrane protein DUF106 RIC1 PF07064.8 EGC38182.1 - 2.6e-74 249.9 0.0 6.7e-74 248.5 0.0 1.7 1 0 0 1 1 1 1 RIC1 Ank_2 PF12796.2 EGC38183.1 - 6.7e-35 119.3 6.7 2.6e-10 40.4 1.2 6.5 2 2 2 4 4 4 4 Ankyrin repeats (3 copies) Ank PF00023.25 EGC38183.1 - 8.9e-31 104.1 0.0 8.6e-05 22.1 0.0 8.6 8 2 0 8 8 8 6 Ankyrin repeat Ank_4 PF13637.1 EGC38183.1 - 1.1e-30 105.4 1.8 6.7e-08 32.8 0.0 7.2 6 1 1 7 7 7 5 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC38183.1 - 4.4e-26 88.3 11.5 0.00027 20.9 0.0 9.5 10 0 0 10 10 10 7 Ankyrin repeat Ank_5 PF13857.1 EGC38183.1 - 5.7e-22 77.2 1.5 8.5e-05 22.6 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeats (many copies) FAM110_C PF14160.1 EGC38183.1 - 0.008 17.1 0.5 0.008 17.1 0.3 3.2 4 0 0 4 4 4 1 Centrosome-associated C terminus SR-25 PF10500.4 EGC38183.1 - 0.051 13.0 7.8 0.096 12.1 4.9 1.9 2 0 0 2 2 2 0 Nuclear RNA-splicing-associated protein bZIP_1 PF00170.16 EGC38185.1 - 7e-13 48.3 6.0 7e-13 48.3 4.1 2.2 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGC38185.1 - 1.4e-11 44.0 4.8 5.4e-11 42.1 3.3 2.1 1 0 0 1 1 1 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGC38185.1 - 0.00044 20.4 4.5 0.00044 20.4 3.1 3.2 3 1 1 4 4 4 1 bZIP Maf transcription factor Adap_comp_sub PF00928.16 EGC38186.1 - 4.3e-72 242.3 0.1 5.2e-72 242.1 0.1 1.1 1 0 0 1 1 1 1 Adaptor complexes medium subunit family Clat_adaptor_s PF01217.15 EGC38186.1 - 0.00025 20.7 0.2 0.00046 19.9 0.2 1.5 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Methyltransf_11 PF08241.7 EGC38187.1 - 1.8e-15 57.2 0.0 6.9e-15 55.3 0.0 2.0 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38187.1 - 2.5e-11 43.5 0.0 5.4e-11 42.4 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC38187.1 - 2.8e-10 40.5 0.3 9.2e-10 38.8 0.0 2.0 3 0 0 3 3 3 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38187.1 - 1.6e-08 35.1 0.0 4.3e-08 33.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38187.1 - 2.5e-08 33.6 0.3 7.3e-08 32.1 0.2 2.0 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC38187.1 - 3.5e-07 29.5 0.0 6.4e-07 28.7 0.0 1.4 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family FtsJ PF01728.14 EGC38187.1 - 5.6e-05 23.2 0.0 0.00012 22.1 0.0 1.5 1 1 0 1 1 1 1 FtsJ-like methyltransferase Methyltransf_26 PF13659.1 EGC38187.1 - 0.00045 20.2 0.0 0.0011 18.9 0.0 1.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC38187.1 - 0.00053 20.3 0.0 0.0016 18.7 0.0 1.8 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC38187.1 - 0.00058 19.5 0.0 0.0012 18.5 0.0 1.5 1 0 0 1 1 1 1 Hypothetical methyltransferase DREV PF05219.7 EGC38187.1 - 0.0025 16.7 0.4 0.17 10.6 0.0 2.7 2 1 0 2 2 2 1 DREV methyltransferase PCMT PF01135.14 EGC38187.1 - 0.0073 15.8 0.0 0.011 15.3 0.0 1.3 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) RrnaAD PF00398.15 EGC38187.1 - 0.008 15.2 0.1 0.016 14.2 0.0 1.6 2 0 0 2 2 2 1 Ribosomal RNA adenine dimethylase SCO1-SenC PF02630.9 EGC38187.1 - 0.013 15.1 0.7 0.02 14.5 0.0 1.6 2 0 0 2 2 2 0 SCO1/SenC Methyltransf_PK PF05891.7 EGC38187.1 - 0.032 13.5 0.0 0.076 12.3 0.0 1.6 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase Mhr1 PF12829.2 EGC38189.1 - 0.0048 16.6 0.5 0.0067 16.2 0.4 1.2 1 0 0 1 1 1 1 Transcriptional regulation of mitochondrial recombination FHIPEP PF00771.15 EGC38190.1 - 0.13 10.5 14.4 0.15 10.3 10.0 1.0 1 0 0 1 1 1 0 FHIPEP family DUF843 PF05814.6 EGC38190.1 - 0.16 11.7 0.4 0.43 10.4 0.3 1.7 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) SpoIIIAH PF12685.2 EGC38190.1 - 0.56 9.6 16.9 0.017 14.6 5.8 1.9 1 1 1 2 2 2 0 SpoIIIAH-like protein ETRAMP PF09716.5 EGC38190.1 - 1.2 9.0 7.3 15 5.6 5.1 2.6 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF3373 PF11853.3 EGC38190.1 - 3.2 6.1 13.0 3.9 5.8 9.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3373) ETRAMP PF09716.5 EGC38191.1 - 0.012 15.5 2.0 0.012 15.5 1.4 4.0 2 2 1 3 3 3 0 Malarial early transcribed membrane protein (ETRAMP) CCSMST1 PF15013.1 EGC38191.1 - 0.099 12.5 0.1 0.099 12.5 0.1 2.7 3 0 0 3 3 3 0 CCSMST1 family MutS_V PF00488.16 EGC38193.1 - 2.1e-93 312.0 0.3 3.8e-93 311.2 0.2 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC38193.1 - 1.6e-36 126.0 3.0 5.3e-36 124.3 2.1 2.0 1 0 0 1 1 1 1 MutS domain III MutS_I PF01624.15 EGC38193.1 - 7.8e-36 122.5 0.0 1.7e-35 121.4 0.0 1.6 1 0 0 1 1 1 1 MutS domain I MutS_IV PF05190.13 EGC38193.1 - 2.8e-17 62.6 2.8 2.8e-17 62.6 1.9 2.4 2 0 0 2 2 2 1 MutS family domain IV MutS_II PF05188.12 EGC38193.1 - 9.7e-16 58.0 0.1 2.6e-15 56.7 0.1 1.7 1 0 0 1 1 1 1 MutS domain II PA28_alpha PF02251.13 EGC38193.1 - 0.03 14.5 0.7 0.18 11.9 0.1 2.7 2 0 0 2 2 2 0 Proteasome activator pa28 alpha subunit PRA1 PF03208.14 EGC38194.1 - 9.1e-12 44.5 0.2 1.3e-11 44.0 0.1 1.2 1 0 0 1 1 1 1 PRA1 family protein bZIP_1 PF00170.16 EGC38196.1 - 7.4e-08 32.2 12.9 5.3e-07 29.5 9.0 2.2 1 1 0 1 1 1 1 bZIP transcription factor bZIP_2 PF07716.10 EGC38196.1 - 8.4e-06 25.5 6.3 8.4e-06 25.5 4.4 2.6 2 1 1 3 3 3 2 Basic region leucine zipper bZIP_Maf PF03131.12 EGC38196.1 - 0.0054 16.9 6.8 0.013 15.7 4.7 1.7 1 0 0 1 1 1 1 bZIP Maf transcription factor TetR PF13972.1 EGC38196.1 - 0.051 13.0 0.4 0.085 12.2 0.3 1.3 1 0 0 1 1 1 0 Bacterial transcriptional repressor Pkinase PF00069.20 EGC38197.1 - 1.6e-73 247.0 1.8 2.3e-72 243.2 0.0 2.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38197.1 - 1.9e-37 128.7 0.0 3.6e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC38197.1 - 7.2e-08 31.7 0.0 1.4e-07 30.7 0.0 1.5 1 0 0 1 1 1 1 Kinase-like Kdo PF06293.9 EGC38197.1 - 4e-05 22.7 0.0 7.3e-05 21.9 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC38197.1 - 0.00088 18.6 0.1 0.0039 16.5 0.0 2.1 2 0 0 2 2 2 1 PhoP regulatory network protein YrbL APH PF01636.18 EGC38197.1 - 0.0024 17.6 0.0 0.0067 16.1 0.0 1.7 2 0 0 2 2 2 1 Phosphotransferase enzyme family RRM_1 PF00076.17 EGC38198.1 - 3.4e-40 135.5 2.4 3.8e-17 61.6 0.2 3.9 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38198.1 - 1e-34 118.3 0.2 1.7e-14 53.5 0.0 3.9 3 0 0 3 3 3 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38198.1 - 8.9e-29 99.1 0.9 1.7e-11 43.8 0.0 3.6 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) SAP PF02037.22 EGC38198.1 - 2.1e-13 49.4 5.5 2.7e-12 45.8 0.5 2.9 3 0 0 3 3 3 2 SAP domain Peptidase_S9 PF00326.16 EGC38200.1 - 6.3e-25 87.6 0.0 1.3e-24 86.6 0.0 1.6 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC38200.1 - 5.3e-11 42.4 0.0 9e-11 41.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC38200.1 - 1.4e-07 31.6 0.0 3.1e-07 30.5 0.0 1.5 1 1 0 1 1 1 1 Alpha/beta hydrolase family BAAT_C PF08840.6 EGC38200.1 - 9e-07 28.8 0.1 4.4e-06 26.5 0.0 2.1 2 0 0 2 2 2 1 BAAT / Acyl-CoA thioester hydrolase C terminal Abhydrolase_1 PF00561.15 EGC38200.1 - 2.5e-05 23.9 0.1 0.014 15.0 0.0 2.5 1 1 1 2 2 2 2 alpha/beta hydrolase fold AXE1 PF05448.7 EGC38200.1 - 0.0006 18.4 0.0 0.01 14.3 0.0 2.8 1 1 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_3 PF07859.8 EGC38200.1 - 0.0045 16.5 0.0 0.019 14.5 0.0 2.0 2 0 0 2 2 2 1 alpha/beta hydrolase fold PD40 PF07676.7 EGC38200.1 - 0.0045 16.6 0.1 0.045 13.4 0.0 2.6 2 0 0 2 2 2 1 WD40-like Beta Propeller Repeat DLH PF01738.13 EGC38200.1 - 0.022 14.0 0.0 0.14 11.4 0.0 2.0 2 0 0 2 2 2 0 Dienelactone hydrolase family TetR_C_4 PF08359.6 EGC38201.1 - 0.087 12.7 2.7 0.17 11.7 0.1 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Zip PF02535.17 EGC38201.1 - 0.65 8.9 2.0 0.67 8.9 0.9 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter CLN5 PF15014.1 EGC38202.1 - 0.0012 18.3 1.3 0.0014 18.0 0.9 1.1 1 0 0 1 1 1 1 Ceroid-lipofuscinosis neuronal protein 5 DUF3138 PF11336.3 EGC38202.1 - 0.27 9.3 1.8 0.45 8.6 0.4 1.7 1 1 0 2 2 2 0 Protein of unknown function (DUF3138) zinc_ribbon_6 PF14599.1 EGC38203.1 - 1e-17 63.6 0.2 1e-17 63.6 0.1 3.7 3 1 0 3 3 3 1 Zinc-ribbon zf-CHY PF05495.7 EGC38203.1 - 3.8e-16 58.9 24.3 3.8e-16 58.9 16.9 4.3 3 2 1 4 4 4 1 CHY zinc finger zf-RING_2 PF13639.1 EGC38203.1 - 3e-10 39.7 4.5 3e-10 39.7 3.1 4.9 3 1 0 3 3 3 1 Ring finger domain zf-C3HC4 PF00097.20 EGC38203.1 - 2.7e-07 30.1 5.2 2.7e-07 30.1 3.6 5.9 3 1 2 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38203.1 - 3.6e-07 30.0 5.8 3.6e-07 30.0 4.0 5.5 4 1 1 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38203.1 - 3.3e-06 26.7 4.6 3.3e-06 26.7 3.2 5.8 4 2 0 5 5 5 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC38203.1 - 0.00011 21.7 4.8 0.00011 21.7 3.3 5.4 4 2 0 4 4 4 1 RING/Ubox like zinc-binding domain 2-oxoacid_dh PF00198.18 EGC38204.1 - 7.5e-80 267.5 0.0 1.2e-79 266.8 0.0 1.3 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGC38204.1 - 1.2e-17 63.3 0.1 2.6e-17 62.2 0.1 1.6 1 0 0 1 1 1 1 Biotin-requiring enzyme E3_binding PF02817.12 EGC38204.1 - 5.5e-13 48.3 0.0 1.5e-12 46.9 0.0 1.8 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGC38204.1 - 0.01 15.4 0.0 6.4 6.5 0.0 2.5 1 1 1 2 2 2 0 Biotin-lipoyl like ATP-gua_Ptrans PF00217.14 EGC38204.1 - 0.071 12.4 0.0 0.19 11.0 0.0 1.6 1 0 0 1 1 1 0 ATP:guanido phosphotransferase, C-terminal catalytic domain DUF1908 PF08926.6 EGC38204.1 - 0.18 10.5 1.7 0.36 9.5 1.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF1908) Pheromone PF08015.6 EGC38204.1 - 1.4 9.8 7.4 0.27 12.0 0.4 3.0 3 0 0 3 3 3 0 Fungal mating-type pheromone Ribosomal_L28 PF00830.14 EGC38205.1 - 7.2e-20 70.5 0.1 1.1e-19 69.9 0.1 1.3 1 0 0 1 1 1 1 Ribosomal L28 family Band_7_1 PF13421.1 EGC38205.1 - 0.038 13.4 0.0 0.047 13.2 0.0 1.0 1 0 0 1 1 1 0 SPFH domain-Band 7 family Fcf1 PF04900.7 EGC38205.1 - 0.062 13.3 0.0 0.086 12.9 0.0 1.4 1 0 0 1 1 1 0 Fcf1 ABC1 PF03109.11 EGC38206.1 - 2.7e-31 108.0 0.0 6e-31 106.8 0.0 1.6 1 0 0 1 1 1 1 ABC1 family APH PF01636.18 EGC38206.1 - 0.16 11.6 0.0 2.1 7.9 0.0 2.5 3 0 0 3 3 3 0 Phosphotransferase enzyme family Ricin_B_lectin PF00652.17 EGC38207.1 - 4.1e-11 42.9 3.4 8.7e-11 41.9 2.4 1.6 1 0 0 1 1 1 1 Ricin-type beta-trefoil lectin domain RicinB_lectin_2 PF14200.1 EGC38207.1 - 0.59 10.5 6.9 0.51 10.7 3.2 2.1 2 0 0 2 2 2 0 Ricin-type beta-trefoil lectin domain-like Asp PF00026.18 EGC38208.1 - 0.042 13.0 0.1 0.055 12.6 0.0 1.1 1 0 0 1 1 1 0 Eukaryotic aspartyl protease Ank_3 PF13606.1 EGC38210.1 - 0.017 15.2 0.1 6.2 7.3 0.0 3.7 2 0 0 2 2 2 0 Ankyrin repeat SAP30_Sin3_bdg PF13867.1 EGC38210.1 - 0.019 14.8 0.3 0.078 12.8 0.2 2.0 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Ank_2 PF12796.2 EGC38210.1 - 0.072 13.4 0.2 0.27 11.6 0.0 2.0 2 0 0 2 2 2 0 Ankyrin repeats (3 copies) MCRS_N PF13325.1 EGC38211.1 - 2e-17 63.3 3.7 2e-17 63.3 2.6 3.5 3 1 0 3 3 3 1 N-terminal region of micro-spherule protein FHA PF00498.21 EGC38211.1 - 3.7e-08 33.3 0.1 2.5e-07 30.6 0.1 2.5 2 0 0 2 2 2 1 FHA domain MIF4G PF02854.14 EGC38212.1 - 4.1e-40 137.4 8.6 4.1e-40 137.4 6.0 2.8 3 0 0 3 3 3 1 MIF4G domain Peptidase_C39_2 PF13529.1 EGC38213.1 - 3.9e-10 40.2 0.4 5.6e-10 39.7 0.3 1.3 1 0 0 1 1 1 1 Peptidase_C39 like family Transpep_BrtH PF14399.1 EGC38213.1 - 0.00071 18.9 0.2 0.0012 18.1 0.2 1.5 1 1 0 1 1 1 1 NlpC/p60-like transpeptidase Guanylate_cyc_2 PF09778.4 EGC38213.1 - 0.065 12.4 0.0 0.09 11.9 0.0 1.2 1 0 0 1 1 1 0 Guanylylate cyclase SPC12 PF06645.8 EGC38213.1 - 0.11 12.2 0.1 0.28 11.0 0.1 1.7 1 0 0 1 1 1 0 Microsomal signal peptidase 12 kDa subunit (SPC12) ATP11 PF06644.6 EGC38214.1 - 2.2e-59 201.1 0.1 2.9e-59 200.7 0.1 1.1 1 0 0 1 1 1 1 ATP11 protein DUF4300 PF14133.1 EGC38215.1 - 0.073 12.3 6.2 0.023 13.9 2.0 2.0 3 0 0 3 3 3 0 Domain of unknown function (DUF4300) Glyco_hydro_16 PF00722.16 EGC38216.1 - 5.3e-33 113.8 0.6 7.5e-33 113.3 0.4 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 16 SKN1 PF03935.10 EGC38216.1 - 3.1e-21 75.1 4.8 1.1e-14 53.4 0.2 2.1 2 0 0 2 2 2 2 Beta-glucan synthesis-associated protein (SKN1) WD40 PF00400.27 EGC38217.1 - 6.3e-68 222.4 20.9 7.1e-11 41.5 0.0 8.2 8 0 0 8 8 8 7 WD domain, G-beta repeat eIF2A PF08662.6 EGC38217.1 - 1.2e-09 38.1 7.3 0.0011 18.7 0.1 4.9 2 1 3 5 5 5 4 Eukaryotic translation initiation factor eIF2A LisH PF08513.6 EGC38217.1 - 1.5e-09 37.2 1.0 3.1e-09 36.2 0.7 1.6 1 0 0 1 1 1 1 LisH Atrophin-1 PF03154.10 EGC38217.1 - 9e-06 24.1 12.7 1.2e-05 23.7 8.8 1.1 1 0 0 1 1 1 1 Atrophin-1 family RAB3GAP2_N PF14655.1 EGC38217.1 - 0.052 12.5 0.0 0.052 12.5 0.0 1.9 2 0 0 2 2 2 0 Rab3 GTPase-activating protein regulatory subunit N-terminus SprA-related PF12118.3 EGC38217.1 - 0.48 9.7 11.0 0.66 9.2 7.6 1.1 1 0 0 1 1 1 0 SprA-related family Sec62 PF03839.11 EGC38217.1 - 1.2 8.5 12.2 2.1 7.6 8.5 1.4 1 0 0 1 1 1 0 Translocation protein Sec62 Peptidase_U57 PF05582.7 EGC38217.1 - 3 6.7 6.8 5.1 5.9 4.7 1.3 1 0 0 1 1 1 0 YabG peptidase U57 CDC45 PF02724.9 EGC38217.1 - 4.5 5.1 11.4 6.4 4.6 7.9 1.1 1 0 0 1 1 1 0 CDC45-like protein DDHD PF02862.12 EGC38217.1 - 5 6.8 9.3 8.3 6.1 6.4 1.3 1 0 0 1 1 1 0 DDHD domain Pkinase PF00069.20 EGC38218.1 - 1.3e-76 257.2 0.0 1.6e-76 256.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38218.1 - 5.8e-38 130.4 0.0 7.5e-38 130.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase FHA PF00498.21 EGC38218.1 - 3.5e-10 39.8 0.1 6.8e-10 38.9 0.1 1.5 1 0 0 1 1 1 1 FHA domain Kinase-like PF14531.1 EGC38218.1 - 1.1e-06 27.7 0.0 2.4e-06 26.7 0.0 1.5 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EGC38218.1 - 1.2e-06 27.7 0.0 2e-06 27.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC38218.1 - 0.011 15.0 0.1 0.026 13.8 0.1 1.5 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3136 PF11334.3 EGC38218.1 - 0.015 14.6 0.0 0.033 13.6 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3136) EcKinase PF02958.15 EGC38218.1 - 0.06 12.4 0.0 0.17 10.9 0.0 1.7 1 1 1 2 2 2 0 Ecdysteroid kinase adh_short PF00106.20 EGC38219.1 - 2.8e-25 89.1 0.0 3.6e-25 88.7 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC38219.1 - 3.4e-14 53.1 0.0 5.1e-14 52.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC38219.1 - 9e-08 31.9 0.0 1.5e-07 31.2 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC38219.1 - 2.4e-07 30.2 0.0 2.4e-06 26.9 0.0 2.0 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC38219.1 - 1.6e-05 24.9 0.0 3.2e-05 24.0 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC38219.1 - 0.00099 18.0 0.0 0.0015 17.4 0.0 1.2 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase PF01370.16 EGC38219.1 - 0.0037 16.7 0.0 0.0064 15.9 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family Polysacc_synt_2 PF02719.10 EGC38219.1 - 0.021 13.7 0.0 0.03 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Ribosomal_L9_N PF01281.14 EGC38219.1 - 0.022 14.0 0.0 3.6 6.9 0.0 2.4 2 0 0 2 2 2 0 Ribosomal protein L9, N-terminal domain zf-TRAF PF02176.13 EGC38220.1 - 5.5e-16 58.6 24.0 1.4e-12 47.7 3.8 3.4 2 1 1 3 3 3 2 TRAF-type zinc finger Sina PF03145.11 EGC38220.1 - 0.00048 19.8 2.3 0.00048 19.8 1.6 3.4 1 1 1 3 3 3 2 Seven in absentia protein family DUF3996 PF13161.1 EGC38220.1 - 0.0015 18.1 0.3 0.0039 16.8 0.2 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF3996) Prefoldin_2 PF01920.15 EGC38220.1 - 0.023 14.4 0.2 0.13 12.0 0.0 2.1 2 0 0 2 2 2 0 Prefoldin subunit MATH PF00917.21 EGC38220.1 - 0.05 13.8 9.0 0.074 13.2 5.5 1.9 1 1 1 2 2 2 0 MATH domain zf-C2H2_4 PF13894.1 EGC38220.1 - 4.6 7.7 9.9 7.9 7.0 0.0 4.0 3 1 0 3 3 3 0 C2H2-type zinc finger zf-TRAF PF02176.13 EGC38221.1 - 1.7e-16 60.3 34.2 3.6e-12 46.4 4.5 5.0 3 2 2 5 5 5 3 TRAF-type zinc finger Sina PF03145.11 EGC38221.1 - 0.0012 18.5 2.9 0.0012 18.5 2.0 3.5 1 1 1 3 3 3 2 Seven in absentia protein family Prefoldin_2 PF01920.15 EGC38221.1 - 0.0053 16.4 1.4 0.069 12.9 0.0 2.5 2 0 0 2 2 2 1 Prefoldin subunit TPR_MLP1_2 PF07926.7 EGC38221.1 - 0.056 13.1 2.3 0.21 11.3 0.5 2.1 2 0 0 2 2 2 0 TPR/MLP1/MLP2-like protein zf-C4 PF00105.13 EGC38221.1 - 6.3 7.1 26.2 1.6 9.0 5.7 3.9 2 1 1 3 3 3 0 Zinc finger, C4 type (two domains) zf-TRAF PF02176.13 EGC38222.1 - 5e-11 42.8 46.3 2.2e-08 34.3 6.1 4.9 2 2 3 5 5 5 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC38222.1 - 0.00065 19.6 9.9 0.00065 19.6 6.8 4.1 4 1 0 4 4 4 1 Zinc finger, C3HC4 type (RING finger) DnaA_N PF11638.3 EGC38222.1 - 0.071 12.6 0.5 12 5.6 0.1 2.6 2 0 0 2 2 2 0 DnaA N-terminal domain Cyclin_N PF00134.18 EGC38223.1 - 1.4e-09 37.5 0.0 3.6e-06 26.5 0.0 2.4 2 0 0 2 2 2 2 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC38223.1 - 0.00011 22.0 0.1 0.00023 21.0 0.1 1.5 1 0 0 1 1 1 1 Cyclin, C-terminal domain RdRP PF05183.7 EGC38224.1 - 2.9e-112 376.2 0.0 6.2e-112 375.1 0.0 1.6 1 0 0 1 1 1 1 RNA dependent RNA polymerase DEAD PF00270.24 EGC38224.1 - 9.1e-19 67.5 0.1 3e-18 65.8 0.1 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase ResIII PF04851.10 EGC38224.1 - 1.2e-17 64.3 0.1 1.2e-17 64.3 0.1 5.1 5 0 0 5 5 5 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGC38224.1 - 4.6e-16 58.4 0.0 2.5e-15 56.0 0.0 2.3 1 0 0 1 1 1 1 Helicase conserved C-terminal domain DUF2924 PF11149.3 EGC38224.1 - 0.077 13.0 0.1 0.2 11.6 0.1 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2924) EGF_2 PF07974.8 EGC38225.1 - 0.0016 18.5 11.1 0.0028 17.7 7.7 1.3 1 0 0 1 1 1 1 EGF-like domain Complex1_LYR PF05347.10 EGC38226.1 - 5.5e-10 38.8 0.5 2.2e-09 36.9 0.3 1.8 1 1 1 2 2 2 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC38226.1 - 3.2e-08 33.6 0.7 2.4e-07 30.8 0.5 2.0 1 1 1 2 2 2 1 Complex1_LYR-like Complex1_LYR_2 PF13233.1 EGC38226.1 - 0.0026 18.2 0.2 0.0041 17.5 0.1 1.3 1 1 0 1 1 1 1 Complex1_LYR-like NAC PF01849.13 EGC38229.1 - 5.7e-14 51.3 0.3 2e-13 49.6 0.1 1.9 2 0 0 2 2 2 1 NAC domain Fes1 PF08609.5 EGC38229.1 - 0.015 15.7 0.1 2.3 8.7 0.0 2.3 2 0 0 2 2 2 0 Nucleotide exchange factor Fes1 MMR_HSR1 PF01926.18 EGC38230.1 - 8.1e-08 32.2 0.7 8.1e-08 32.2 0.5 3.7 4 2 0 4 4 4 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC38230.1 - 4.4e-07 29.2 0.2 1.5e-05 24.2 0.1 2.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGC38230.1 - 0.0035 18.1 0.0 0.0035 18.1 0.0 3.7 4 2 0 4 4 4 1 AAA domain AAA_14 PF13173.1 EGC38230.1 - 0.02 14.7 0.1 0.02 14.7 0.1 3.6 3 1 0 3 3 3 0 AAA domain Miro PF08477.8 EGC38230.1 - 0.023 15.1 0.3 0.023 15.1 0.2 4.5 4 1 0 4 4 4 0 Miro-like protein AAA_22 PF13401.1 EGC38230.1 - 0.028 14.5 0.3 0.32 11.1 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC38230.1 - 0.048 13.5 0.2 0.21 11.4 0.0 2.1 3 0 0 3 3 3 0 AAA domain ABC_tran PF00005.22 EGC38230.1 - 0.057 13.7 0.0 0.057 13.7 0.0 3.8 3 1 0 3 3 2 0 ABC transporter DUF2877 PF11392.3 EGC38230.1 - 0.16 12.2 0.2 0.52 10.5 0.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF2877) ATP_bind_1 PF03029.12 EGC38230.1 - 0.17 11.3 4.4 3.6 7.0 0.2 3.8 3 1 0 3 3 3 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGC38230.1 - 0.25 11.6 0.0 0.25 11.6 0.0 5.1 3 2 2 5 5 4 0 AAA domain DUF572 PF04502.8 EGC38231.1 - 2.5e-58 197.8 17.3 2.9e-58 197.6 12.0 1.0 1 0 0 1 1 1 1 Family of unknown function (DUF572) Peptidase_C97 PF05903.9 EGC38232.1 - 4.5e-40 136.8 0.0 8.8e-40 135.9 0.0 1.5 1 0 0 1 1 1 1 PPPDE putative peptidase domain PUL PF08324.6 EGC38232.1 - 2.4e-27 95.3 9.7 2.4e-27 95.3 6.7 1.5 2 0 0 2 2 2 1 PUL domain LRAT PF04970.8 EGC38232.1 - 0.011 15.7 2.1 0.032 14.1 0.4 2.3 2 0 0 2 2 2 0 Lecithin retinol acyltransferase ABC2_membrane PF01061.19 EGC38233.1 - 7.3e-78 260.5 65.5 6.5e-45 152.8 15.3 3.3 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC38233.1 - 4.2e-45 153.4 0.7 3.3e-22 79.2 0.0 2.5 2 0 0 2 2 2 2 ABC transporter DUF258 PF03193.11 EGC38233.1 - 6.7e-08 31.8 0.2 0.0017 17.5 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC38233.1 - 1.1e-07 31.4 0.0 0.0043 16.4 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_16 PF13191.1 EGC38233.1 - 5.6e-07 29.7 0.0 0.01 15.8 0.0 2.3 2 0 0 2 2 2 2 AAA ATPase domain AAA_33 PF13671.1 EGC38233.1 - 6e-06 26.1 0.1 0.039 13.8 0.0 2.8 2 0 0 2 2 2 2 AAA domain AAA_18 PF13238.1 EGC38233.1 - 6.3e-06 26.5 3.0 0.026 14.8 0.0 3.5 3 0 0 3 3 3 2 AAA domain AAA_22 PF13401.1 EGC38233.1 - 8.6e-06 25.9 1.1 0.061 13.4 0.2 3.0 2 2 0 2 2 2 2 AAA domain SMC_N PF02463.14 EGC38233.1 - 1.1e-05 24.7 5.6 0.0083 15.3 0.9 3.0 2 2 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC38233.1 - 1.3e-05 24.6 0.7 0.0032 16.9 0.0 2.6 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_17 PF13207.1 EGC38233.1 - 3.6e-05 24.5 1.3 0.3 11.9 0.0 3.3 3 0 0 3 3 3 2 AAA domain RNA_helicase PF00910.17 EGC38233.1 - 0.00025 21.2 3.7 0.073 13.2 0.0 3.5 3 0 0 3 3 3 1 RNA helicase MMR_HSR1 PF01926.18 EGC38233.1 - 0.00046 20.1 0.3 1.2 9.0 0.0 2.9 2 1 0 2 2 2 2 50S ribosome-binding GTPase AAA PF00004.24 EGC38233.1 - 0.00059 20.0 3.5 0.015 15.5 0.2 3.5 3 1 0 3 3 3 1 ATPase family associated with various cellular activities (AAA) AAA_21 PF13304.1 EGC38233.1 - 0.0008 19.4 33.6 0.00087 19.3 0.7 7.0 6 2 1 7 7 5 2 AAA domain AAA_28 PF13521.1 EGC38233.1 - 0.0011 18.9 1.0 1.5 8.7 0.1 2.3 2 0 0 2 2 2 2 AAA domain Zeta_toxin PF06414.7 EGC38233.1 - 0.0014 17.7 0.2 0.11 11.5 0.0 2.3 2 0 0 2 2 2 1 Zeta toxin AAA_5 PF07728.9 EGC38233.1 - 0.0017 18.1 1.0 0.28 10.9 0.0 2.8 2 0 0 2 2 2 1 AAA domain (dynein-related subfamily) Arch_ATPase PF01637.13 EGC38233.1 - 0.0027 17.4 9.5 0.0037 17.0 0.1 3.6 4 0 0 4 4 4 1 Archaeal ATPase UPF0079 PF02367.12 EGC38233.1 - 0.0033 17.0 1.5 0.67 9.6 0.0 2.5 2 0 0 2 2 2 1 Uncharacterised P-loop hydrolase UPF0079 NACHT PF05729.7 EGC38233.1 - 0.0045 16.6 1.1 1.2 8.7 0.0 2.4 2 0 0 2 2 2 1 NACHT domain AAA_15 PF13175.1 EGC38233.1 - 0.0058 15.7 0.1 0.017 14.1 0.2 5.9 4 1 2 6 6 5 2 AAA ATPase domain PduV-EutP PF10662.4 EGC38233.1 - 0.0065 15.9 2.6 1.2 8.6 0.0 3.0 3 0 0 3 3 3 1 Ethanolamine utilisation - propanediol utilisation SbcCD_C PF13558.1 EGC38233.1 - 0.033 14.1 0.0 0.13 12.1 0.0 2.1 1 0 0 1 1 1 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EGC38233.1 - 0.038 13.7 0.5 5.5 6.8 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain PDR_CDR PF06422.7 EGC38233.1 - 0.042 13.4 3.4 0.24 11.0 0.3 2.6 2 0 0 2 2 2 0 CDR ABC transporter PRK PF00485.13 EGC38233.1 - 0.044 13.3 1.3 1.2 8.6 0.0 2.6 3 0 0 3 3 2 0 Phosphoribulokinase / Uridine kinase family AAA_30 PF13604.1 EGC38233.1 - 0.065 12.7 0.0 9.2 5.7 0.1 2.3 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGC38233.1 - 0.069 12.5 1.8 9.6 5.5 0.1 2.8 2 1 0 3 3 3 0 AAA-like domain cobW PF02492.14 EGC38233.1 - 0.14 11.5 5.1 3.5 7.0 0.2 2.7 3 0 0 3 3 2 0 CobW/HypB/UreG, nucleotide-binding domain IstB_IS21 PF01695.12 EGC38233.1 - 0.15 11.4 0.0 6.1 6.2 0.0 2.5 2 0 0 2 2 2 0 IstB-like ATP binding protein CCSMST1 PF15013.1 EGC38233.1 - 0.29 11.0 3.1 2.4 8.1 0.1 2.9 3 0 0 3 3 2 0 CCSMST1 family RuvB_N PF05496.7 EGC38233.1 - 0.32 9.9 1.2 1.4 7.9 0.1 2.1 2 0 0 2 2 2 0 Holliday junction DNA helicase ruvB N-terminus DUF87 PF01935.12 EGC38233.1 - 2.7 7.7 10.0 3.9 7.2 0.0 3.3 3 0 0 3 3 3 0 Domain of unknown function DUF87 TPR_12 PF13424.1 EGC38235.1 - 7.6e-12 44.9 7.3 9.5e-06 25.4 0.1 3.6 2 1 1 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC38235.1 - 1.6e-06 27.6 13.4 0.18 11.8 0.2 5.4 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGC38235.1 - 3.1e-05 23.3 13.0 0.05 13.2 0.0 5.6 5 1 1 6 6 6 2 Tetratricopeptide repeat TPR_11 PF13414.1 EGC38235.1 - 0.00011 21.7 13.2 0.007 15.9 1.1 3.9 1 1 3 4 4 4 4 TPR repeat TPR_16 PF13432.1 EGC38235.1 - 0.0028 18.2 1.3 2.8 8.7 0.1 3.7 3 1 0 3 3 3 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38235.1 - 0.0035 17.6 0.6 20 5.6 0.0 3.8 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC38235.1 - 0.0046 17.4 0.0 21 6.1 0.0 3.8 4 0 0 4 4 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC38235.1 - 0.0085 15.9 2.9 5.6 7.0 0.2 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC38235.1 - 0.043 14.0 2.2 68 4.0 0.0 4.6 3 1 0 3 3 3 0 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38235.1 - 0.14 11.9 16.2 0.22 11.3 0.1 4.8 5 1 0 5 5 5 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC38235.1 - 0.15 11.9 3.3 5.8 6.9 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_4 PF07721.9 EGC38235.1 - 0.18 12.3 0.0 8.3 7.1 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38235.1 - 1.3 9.6 4.2 59 4.4 0.1 4.1 4 0 0 4 4 4 0 Tetratricopeptide repeat Ammonium_transp PF00909.16 EGC38236.1 - 6.9e-54 182.8 18.6 1.1e-53 182.1 12.9 1.2 1 0 0 1 1 1 1 Ammonium Transporter Family DUF4611 PF15387.1 EGC38236.1 - 0.053 13.6 0.3 0.1 12.7 0.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) Allantoicase PF03561.10 EGC38237.1 - 1.6e-100 332.8 0.1 1.4e-54 183.7 0.0 2.0 2 0 0 2 2 2 2 Allantoicase repeat F5_F8_type_C PF00754.20 EGC38237.1 - 9.6e-05 22.2 1.0 0.17 11.7 0.1 2.4 2 0 0 2 2 2 2 F5/8 type C domain DUF1084 PF06454.6 EGC38238.1 - 2.6e-08 33.2 23.1 3.4e-06 26.3 1.0 2.1 1 1 1 2 2 2 2 Protein of unknown function (DUF1084) MAP65_ASE1 PF03999.7 EGC38239.1 - 4.2e-34 118.1 52.1 6.7e-32 110.8 23.1 3.2 1 1 2 3 3 3 2 Microtubule associated protein (MAP65/ASE1 family) XRCC1_N PF01834.11 EGC38239.1 - 0.098 12.1 0.1 0.098 12.1 0.0 2.1 2 0 0 2 2 2 0 XRCC1 N terminal domain Erf4 PF10256.4 EGC38240.1 - 0.00043 20.1 4.5 0.00043 20.1 3.1 3.1 1 1 1 3 3 3 1 Golgin subfamily A member 7/ERF4 family SURF6 PF04935.7 EGC38240.1 - 0.062 12.5 1.2 0.079 12.2 0.8 1.1 1 0 0 1 1 1 0 Surfeit locus protein 6 DUF1083 PF06452.6 EGC38240.1 - 0.33 10.8 2.8 0.45 10.3 1.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1083) DUF1390 PF07150.6 EGC38240.1 - 0.42 9.9 4.3 0.59 9.4 3.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) DUF1616 PF07760.6 EGC38241.1 - 0.001 18.2 0.1 0.0016 17.6 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1616) Erf4 PF10256.4 EGC38241.1 - 0.0013 18.5 2.4 0.0013 18.5 1.7 2.7 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family DUF3278 PF11683.3 EGC38241.1 - 0.01 15.8 1.4 0.029 14.3 0.7 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF3278) GAPT PF11770.3 EGC38241.1 - 0.016 14.9 0.0 0.034 13.8 0.0 1.6 1 0 0 1 1 1 0 GRB2-binding adapter (GAPT) MLANA PF14991.1 EGC38241.1 - 0.058 13.4 0.0 0.15 12.0 0.0 1.7 1 0 0 1 1 1 0 Protein melan-A DUF202 PF02656.10 EGC38241.1 - 0.54 10.5 3.2 0.95 9.7 2.2 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF202) TarH PF02203.10 EGC38241.1 - 9.1 6.0 7.0 2 8.2 1.6 2.2 1 1 1 2 2 2 0 Tar ligand binding domain homologue Peptidase_M20 PF01546.23 EGC38242.1 - 2.4e-32 111.9 0.0 3.2e-32 111.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC38242.1 - 1.2e-10 41.1 0.0 2.3e-10 40.1 0.0 1.4 1 0 0 1 1 1 1 Peptidase dimerisation domain Peptidase_M28 PF04389.12 EGC38242.1 - 0.00036 20.3 0.0 0.0011 18.7 0.0 1.9 3 0 0 3 3 3 1 Peptidase family M28 Myb_DNA-binding PF00249.26 EGC38243.1 - 1.3e-14 53.9 0.0 1.6e-06 28.0 0.0 2.7 2 0 0 2 2 2 2 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC38243.1 - 1.5e-07 31.3 8.9 0.00089 19.3 0.2 3.9 3 0 0 3 3 3 2 Myb-like DNA-binding domain Ceramidase PF05875.7 EGC38245.1 - 2.1e-63 213.9 9.9 2.6e-63 213.6 6.8 1.0 1 0 0 1 1 1 1 Ceramidase PRA1 PF03208.14 EGC38245.1 - 1.3 8.3 8.8 2 7.7 0.6 2.4 2 0 0 2 2 2 0 PRA1 family protein DUF3449 PF11931.3 EGC38246.1 - 4.3e-62 209.1 3.4 4.3e-62 209.1 2.3 3.7 3 1 1 4 4 4 2 Domain of unknown function (DUF3449) SF3a60_bindingd PF12108.3 EGC38246.1 - 2.7e-12 46.0 3.3 1.7e-11 43.4 0.3 2.9 2 0 0 2 2 2 1 Splicing factor SF3a60 binding domain zf-met PF12874.2 EGC38246.1 - 2.3e-10 40.2 9.6 1.3e-08 34.6 1.2 3.1 3 0 0 3 3 3 2 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGC38246.1 - 2.1e-08 34.0 0.5 2.1e-08 34.0 0.3 3.4 3 1 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-C2H2_2 PF12756.2 EGC38246.1 - 0.00089 19.3 5.4 0.16 12.1 0.1 3.4 3 0 0 3 3 3 2 C2H2 type zinc-finger (2 copies) zf-C2H2_6 PF13912.1 EGC38246.1 - 0.07 13.0 0.4 0.07 13.0 0.3 2.4 2 0 0 2 2 2 0 C2H2-type zinc finger Desulfoferrod_N PF06397.7 EGC38246.1 - 0.15 11.4 0.6 0.28 10.6 0.4 1.3 1 0 0 1 1 1 0 Desulfoferrodoxin, N-terminal domain TatD_DNase PF01026.16 EGC38247.1 - 1.1e-59 201.7 0.0 1.4e-59 201.4 0.0 1.1 1 0 0 1 1 1 1 TatD related DNase DUF29 PF01724.11 EGC38247.1 - 0.11 12.3 0.1 15 5.3 0.0 2.6 2 0 0 2 2 2 0 Domain of unknown function DUF29 Menin PF05053.8 EGC38247.1 - 2 6.5 6.4 2.8 6.0 4.4 1.1 1 0 0 1 1 1 0 Menin zf-RING_2 PF13639.1 EGC38248.1 - 1.3e-06 28.1 14.4 1.3e-06 28.1 10.0 2.4 2 1 0 2 2 2 1 Ring finger domain zf-RING_6 PF14835.1 EGC38248.1 - 1.7e-06 27.6 7.4 1.7e-06 27.6 5.1 2.1 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-C3HC4_3 PF13920.1 EGC38248.1 - 2.3e-06 27.1 13.1 2.3e-06 27.1 9.1 2.4 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38248.1 - 3.1e-06 26.7 16.3 3.1e-06 26.7 11.3 2.7 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38248.1 - 0.0002 21.3 17.1 0.0002 21.3 11.9 2.6 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC38248.1 - 0.00027 20.7 16.1 0.00027 20.7 11.1 2.9 2 1 0 3 3 3 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC38248.1 - 0.0038 17.2 7.4 0.0038 17.2 5.1 2.3 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC38248.1 - 0.0041 16.8 16.4 0.0041 16.8 11.3 2.5 2 0 0 2 2 2 1 zinc-RING finger domain DUF1091 PF06477.8 EGC38248.1 - 0.086 13.2 3.4 0.17 12.3 0.3 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1091) SPX PF03105.14 EGC38248.1 - 0.14 11.9 14.5 0.22 11.2 10.0 1.2 1 0 0 1 1 1 0 SPX domain EI24 PF07264.6 EGC38249.1 - 0.018 14.4 6.1 0.028 13.8 4.2 1.2 1 0 0 1 1 1 0 Etoposide-induced protein 2.4 (EI24) Mvb12 PF09452.5 EGC38249.1 - 0.042 14.0 1.8 0.095 12.8 1.3 1.7 1 0 0 1 1 1 0 ESCRT-I subunit Mvb12 Papilloma_E5 PF03025.9 EGC38249.1 - 0.083 12.8 12.1 0.14 12.0 8.4 1.3 1 0 0 1 1 1 0 Papillomavirus E5 PrgI PF12666.2 EGC38249.1 - 0.18 11.9 7.0 0.35 11.0 4.9 1.4 1 0 0 1 1 1 0 PrgI family protein Wzy_C PF04932.10 EGC38249.1 - 3.1 7.5 9.9 4.5 7.0 6.4 1.8 1 1 0 1 1 1 0 O-Antigen ligase Mem_trans PF03547.13 EGC38250.1 - 0.00026 19.3 5.8 0.00035 19.0 4.0 1.1 1 0 0 1 1 1 1 Membrane transport protein DUF975 PF06161.6 EGC38250.1 - 0.11 12.1 6.7 0.17 11.5 4.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF975) DUF2457 PF10446.4 EGC38250.1 - 1.7 7.3 8.9 2.1 6.9 6.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Glucos_trans_II PF14264.1 EGC38251.1 - 0.00021 20.3 0.6 0.00032 19.8 0.4 1.2 1 0 0 1 1 1 1 Glucosyl transferase GtrII Polysacc_synt PF01943.12 EGC38251.1 - 0.0022 17.2 1.0 0.0033 16.7 0.7 1.2 1 0 0 1 1 1 1 Polysaccharide biosynthesis protein Tetraspannin PF00335.15 EGC38251.1 - 0.0055 16.0 2.8 0.014 14.6 0.0 2.1 2 0 0 2 2 2 1 Tetraspanin family Erf4 PF10256.4 EGC38251.1 - 0.011 15.6 0.5 0.029 14.2 0.3 1.9 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF3397 PF11877.3 EGC38251.1 - 0.031 14.2 2.5 0.048 13.6 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3397) ABG_transport PF03806.8 EGC38251.1 - 0.056 11.4 0.5 0.082 10.9 0.3 1.1 1 0 0 1 1 1 0 AbgT putative transporter family CAAD PF14159.1 EGC38251.1 - 0.059 13.0 0.1 0.1 12.2 0.1 1.4 1 0 0 1 1 1 0 CAAD domains of cyanobacterial aminoacyl-tRNA synthetase DUF2244 PF10003.4 EGC38251.1 - 0.073 12.4 0.1 0.12 11.7 0.1 1.3 1 0 0 1 1 1 0 Integral membrane protein (DUF2244) DUF4191 PF13829.1 EGC38251.1 - 0.077 12.1 0.3 0.11 11.6 0.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) DUF4131 PF13567.1 EGC38251.1 - 0.13 11.7 0.0 0.18 11.2 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) DUF2614 PF11023.3 EGC38251.1 - 0.13 12.0 3.3 0.23 11.2 2.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2614) ATPase_gene1 PF09527.5 EGC38251.1 - 0.77 9.5 3.9 1.8 8.4 2.7 1.7 1 1 0 1 1 1 0 Putative F0F1-ATPase subunit (ATPase_gene1) Nucleos_tra2_N PF01773.15 EGC38251.1 - 1.3 9.3 4.4 2.1 8.7 3.0 1.3 1 0 0 1 1 1 0 Na+ dependent nucleoside transporter N-terminus GP41 PF00517.12 EGC38251.1 - 5.2 6.5 9.0 0.19 11.2 0.4 2.1 2 0 0 2 2 2 0 Retroviral envelope protein Aldedh PF00171.17 EGC38252.1 - 2.1e-130 435.1 0.0 2.5e-130 434.9 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family Pkinase PF00069.20 EGC38253.1 - 4e-40 137.5 2.1 4.7e-32 111.1 0.5 2.3 2 0 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38253.1 - 1.3e-28 99.8 1.9 5.6e-28 97.7 1.3 1.8 1 1 0 1 1 1 1 Protein tyrosine kinase Acetyltransf_1 PF00583.19 EGC38253.1 - 1e-06 28.6 0.0 2.1e-06 27.6 0.0 1.5 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_7 PF13508.1 EGC38253.1 - 3.3e-06 27.1 0.0 9.3e-06 25.7 0.0 1.8 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Methyltransf_12 PF08242.7 EGC38253.1 - 0.024 15.1 1.0 0.087 13.3 0.7 1.9 1 0 0 1 1 1 0 Methyltransferase domain Acetyltransf_10 PF13673.1 EGC38253.1 - 0.14 12.2 0.0 0.34 11.0 0.0 1.6 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain RhoGAP PF00620.22 EGC38256.1 - 2e-24 85.9 0.1 1.3e-23 83.3 0.0 2.5 2 0 0 2 2 2 1 RhoGAP domain FCH PF00611.18 EGC38256.1 - 3.8e-15 55.8 2.6 3.8e-15 55.8 1.8 3.4 5 1 0 5 5 5 1 Fes/CIP4, and EFC/F-BAR homology domain ParD PF09386.5 EGC38257.1 - 0.1 12.7 0.1 0.22 11.6 0.1 1.6 1 0 0 1 1 1 0 Antitoxin ParD WD40 PF00400.27 EGC38258.1 - 8.5e-56 183.9 17.8 3.4e-11 42.5 0.0 8.3 8 0 0 8 8 8 8 WD domain, G-beta repeat eIF2A PF08662.6 EGC38258.1 - 8.3e-08 32.1 2.4 0.0056 16.4 0.0 3.5 2 2 2 4 4 4 3 Eukaryotic translation initiation factor eIF2A OTU PF02338.14 EGC38259.1 - 3.7e-12 46.9 0.0 3.7e-12 46.9 0.0 2.9 2 1 0 2 2 2 1 OTU-like cysteine protease Band_3_cyto PF07565.8 EGC38259.1 - 0.94 8.9 15.8 1.5 8.2 11.0 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain PAT1 PF09770.4 EGC38259.1 - 1.8 6.7 44.8 2.2 6.4 31.0 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Med15 PF09606.5 EGC38259.1 - 3 5.9 62.6 3.9 5.5 43.4 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal UAA PF08449.6 EGC38260.1 - 1.9e-79 266.7 21.3 2.3e-79 266.4 14.8 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGC38260.1 - 3.1e-08 33.4 14.4 3.1e-08 33.4 9.9 2.4 2 1 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGC38260.1 - 1.1e-05 25.5 19.2 0.00094 19.2 5.8 2.9 3 0 0 3 3 3 2 EamA-like transporter family FAD_binding_4 PF01565.18 EGC38261.1 - 3.4e-23 81.6 0.0 6.1e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 FAD binding domain BBE PF08031.7 EGC38261.1 - 1.5e-13 50.3 3.7 1.5e-13 50.3 2.6 2.4 3 0 0 3 3 3 1 Berberine and berberine like CLAMP PF14769.1 EGC38261.1 - 0.035 14.2 0.4 9.9 6.3 0.0 3.0 3 0 0 3 3 3 0 Flagellar C1a complex subunit C1a-32 Solute_trans_a PF03619.11 EGC38262.1 - 5.8e-65 219.3 27.8 7.4e-65 218.9 19.3 1.1 1 0 0 1 1 1 1 Organic solute transporter Ostalpha ketoacyl-synt PF00109.21 EGC38263.1 - 2.5e-61 207.3 0.0 3.8e-61 206.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EGC38263.1 - 1.9e-53 180.9 0.0 4.8e-53 179.6 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC38263.1 - 1.8e-49 168.8 0.0 2.7e-49 168.2 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38263.1 - 1.4e-35 121.6 0.0 3.2e-35 120.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38263.1 - 1.9e-26 92.8 0.0 4.2e-24 85.1 0.0 3.2 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC38263.1 - 1.3e-20 74.0 0.0 5.3e-18 65.4 0.0 3.2 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EGC38263.1 - 1.7e-19 70.0 0.0 2.8e-19 69.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGC38263.1 - 6.1e-10 38.9 0.0 8.7e-09 35.1 0.0 2.3 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EGC38263.1 - 3.7e-06 26.6 0.0 7.8e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 EGC38263.1 - 2.2e-05 23.5 0.0 8.4e-05 21.5 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N_2 PF13602.1 EGC38263.1 - 0.00039 21.3 0.0 0.00083 20.2 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC38263.1 - 0.0085 15.1 0.0 0.016 14.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC38264.1 - 2.5e-63 213.8 0.0 3.7e-63 213.3 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38264.1 - 1.2e-47 162.8 0.0 1.7e-47 162.3 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38264.1 - 1.7e-35 121.4 0.0 3.8e-35 120.2 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38264.1 - 3e-26 92.1 0.0 2.3e-25 89.2 0.0 2.1 2 0 0 2 2 2 1 KR domain adh_short PF00106.20 EGC38264.1 - 8.7e-19 68.0 0.0 3.6e-18 66.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGC38264.1 - 1.4e-18 67.1 0.0 2.3e-18 66.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EGC38264.1 - 4.3e-09 35.9 0.0 9e-09 34.9 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38264.1 - 3.5e-07 29.9 0.0 7.5e-07 28.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC38264.1 - 2.2e-05 25.3 0.0 4.5e-05 24.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC38264.1 - 0.0021 17.0 0.0 0.0039 16.2 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain NAD_binding_4 PF07993.7 EGC38265.1 - 1e-53 181.8 0.0 2.9e-53 180.3 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Epimerase PF01370.16 EGC38265.1 - 2e-10 40.5 0.0 3.6e-10 39.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC38265.1 - 1.7e-06 26.9 1.9 1.9e-06 26.8 0.0 2.0 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family RmlD_sub_bind PF04321.12 EGC38265.1 - 4.3e-06 25.8 0.0 0.00012 21.1 0.0 2.1 2 0 0 2 2 2 1 RmlD substrate binding domain Eaf7 PF07904.8 EGC38265.1 - 0.043 13.8 0.3 0.043 13.8 0.2 2.5 3 0 0 3 3 3 0 Chromatin modification-related protein EAF7 Semialdhyde_dh PF01118.19 EGC38265.1 - 0.13 12.5 0.0 0.25 11.6 0.0 1.4 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EGC38266.1 - 2.9e-26 92.2 0.0 4e-26 91.7 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC38266.1 - 1.6e-20 73.7 0.0 2.2e-20 73.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38266.1 - 0.041 14.7 0.0 0.075 13.9 0.0 1.5 1 0 0 1 1 1 0 Zinc-binding dehydrogenase ketoacyl-synt PF00109.21 EGC38267.1 - 1.6e-60 204.7 0.0 2.7e-60 203.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38267.1 - 5.1e-49 167.3 0.0 7.3e-49 166.8 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38267.1 - 2.3e-35 121.0 0.0 5.2e-35 119.8 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain NAD_binding_4 PF07993.7 EGC38267.1 - 8.5e-32 110.0 0.0 2.9e-31 108.2 0.0 2.0 2 0 0 2 2 2 1 Male sterility protein KR PF08659.5 EGC38267.1 - 7.9e-27 94.0 0.0 7.3e-25 87.6 0.0 3.1 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC38267.1 - 2.4e-21 76.3 0.0 3.7e-19 69.2 0.0 2.8 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EGC38267.1 - 6.6e-19 68.1 0.0 1.1e-18 67.4 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_N PF08240.7 EGC38267.1 - 1.2e-05 24.9 0.0 2.7e-05 23.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC38267.1 - 1.4e-05 25.9 0.0 3.1e-05 24.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC38267.1 - 0.0061 15.5 0.0 0.011 14.6 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain eIF3_subunit PF08597.5 EGC38267.1 - 0.99 8.9 4.6 1.6 8.1 0.2 2.9 3 0 0 3 3 3 0 Translation initiation factor eIF3 subunit ketoacyl-synt PF00109.21 EGC38268.1 - 2.7e-59 200.7 0.0 4e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EGC38268.1 - 2.8e-53 180.4 0.0 7.9e-53 178.9 0.0 1.8 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC38268.1 - 3.1e-47 161.4 0.0 4.5e-47 160.9 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38268.1 - 1e-35 122.1 0.0 2.5e-35 120.9 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38268.1 - 2.9e-26 92.2 0.0 2.1e-24 86.1 0.0 3.0 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC38268.1 - 1.2e-20 74.0 0.0 1.7e-18 67.0 0.0 2.9 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EGC38268.1 - 6.1e-19 68.2 0.0 9.7e-19 67.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGC38268.1 - 1.3e-10 41.0 0.0 1.6e-09 37.5 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EGC38268.1 - 3.6e-06 26.7 0.0 7.4e-06 25.6 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain RmlD_sub_bind PF04321.12 EGC38268.1 - 5.5e-06 25.4 0.0 2.8e-05 23.1 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain ADH_zinc_N_2 PF13602.1 EGC38268.1 - 2.3e-05 25.2 0.0 5.1e-05 24.1 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC38268.1 - 0.0089 15.0 0.0 0.017 14.1 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.19 EGC38268.1 - 0.083 13.1 0.0 0.85 9.9 0.0 2.6 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain ketoacyl-synt PF00109.21 EGC38269.1 - 2.6e-59 200.7 0.0 3.8e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain NAD_binding_4 PF07993.7 EGC38269.1 - 1.5e-53 181.2 0.0 3.4e-53 180.1 0.0 1.7 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC38269.1 - 7e-46 157.0 0.0 1e-45 156.4 0.0 1.2 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38269.1 - 2.8e-35 120.7 0.0 6.4e-35 119.5 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38269.1 - 1e-26 93.7 0.0 8.5e-25 87.4 0.0 3.0 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC38269.1 - 4.1e-21 75.6 0.0 7.8e-19 68.2 0.0 3.1 3 0 0 3 3 3 1 short chain dehydrogenase PS-DH PF14765.1 EGC38269.1 - 2e-19 69.9 0.0 3.2e-19 69.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Epimerase PF01370.16 EGC38269.1 - 1.9e-10 40.5 0.0 2.2e-09 37.0 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_zinc_N PF00107.21 EGC38269.1 - 4e-09 36.1 0.0 8.7e-09 35.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38269.1 - 7.3e-07 28.9 0.0 1.7e-06 27.7 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC38269.1 - 0.00028 21.7 0.0 0.0006 20.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase RmlD_sub_bind PF04321.12 EGC38269.1 - 0.00043 19.2 0.0 0.002 17.0 0.0 1.9 1 1 0 1 1 1 1 RmlD substrate binding domain Thiolase_N PF00108.18 EGC38269.1 - 0.0099 14.8 0.0 0.019 13.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.19 EGC38269.1 - 0.097 12.9 0.0 1.7 8.9 0.0 2.7 2 0 0 2 2 2 0 Semialdehyde dehydrogenase, NAD binding domain Thiolase_N PF00108.18 EGC38270.1 - 8e-68 228.2 0.0 1.4e-67 227.5 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGC38270.1 - 5.9e-45 151.6 0.1 1e-44 150.9 0.1 1.4 1 0 0 1 1 1 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGC38270.1 - 0.0017 17.8 0.2 0.0031 17.0 0.1 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain DUF2481 PF10654.4 EGC38270.1 - 0.018 14.7 0.1 0.34 10.6 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2481) ACP_syn_III_C PF08541.5 EGC38270.1 - 0.12 12.3 0.0 0.4 10.7 0.0 1.9 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal HTH_7 PF02796.10 EGC38272.1 - 0.0027 17.5 0.2 0.0074 16.1 0.1 1.7 1 0 0 1 1 1 1 Helix-turn-helix domain of resolvase Phytochelatin PF05023.9 EGC38272.1 - 2 7.3 6.6 4.9 6.0 0.2 2.1 1 1 1 2 2 2 0 Phytochelatin synthase RasGEF PF00617.14 EGC38273.1 - 1.1e-71 240.4 2.2 2.6e-71 239.2 1.6 1.7 1 0 0 1 1 1 1 RasGEF domain RasGEF_N PF00618.15 EGC38273.1 - 1.2e-28 99.1 0.2 1.2e-28 99.1 0.2 4.5 5 0 0 5 5 5 2 RasGEF N-terminal motif DUF771 PF05595.6 EGC38273.1 - 0.012 15.4 3.5 0.47 10.3 0.2 3.1 2 0 0 2 2 2 0 Domain of unknown function (DUF771) adh_short PF00106.20 EGC38274.1 - 1.2e-21 77.3 0.0 3.5e-21 75.8 0.0 1.7 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC38274.1 - 5.1e-09 36.2 0.0 6.8e-09 35.8 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC38274.1 - 3e-06 27.0 0.0 5.3e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC38274.1 - 0.0003 20.8 0.0 0.00044 20.3 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding TrkA_N PF02254.13 EGC38274.1 - 0.012 15.6 0.1 0.036 14.0 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain NAD_binding_4 PF07993.7 EGC38274.1 - 0.02 13.8 0.0 0.033 13.1 0.0 1.3 1 0 0 1 1 1 0 Male sterility protein Polysacc_synt_2 PF02719.10 EGC38274.1 - 0.031 13.1 0.1 0.043 12.6 0.1 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein 3Beta_HSD PF01073.14 EGC38274.1 - 0.055 12.1 0.1 0.076 11.6 0.0 1.2 1 0 0 1 1 1 0 3-beta hydroxysteroid dehydrogenase/isomerase family Shikimate_DH PF01488.15 EGC38274.1 - 0.07 13.2 0.1 0.24 11.5 0.2 1.8 1 1 1 2 2 2 0 Shikimate / quinate 5-dehydrogenase ETRAMP PF09716.5 EGC38275.1 - 1.2 9.1 6.8 4.3 7.3 4.7 1.9 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Chordopox_G3 PF06129.7 EGC38275.1 - 8.2 6.6 10.4 8 6.6 5.4 2.2 2 0 0 2 2 2 0 Chordopoxvirus G3 protein NDUFB10 PF10249.4 EGC38276.1 - 0.016 15.3 1.6 0.028 14.5 1.1 1.5 1 1 0 1 1 1 0 NADH-ubiquinone oxidoreductase subunit 10 ABC2_membrane PF01061.19 EGC38277.1 - 8.4e-92 306.0 59.0 1.7e-47 161.3 19.2 3.4 4 0 0 4 4 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC38277.1 - 8.8e-40 136.1 0.0 4.5e-19 69.1 0.0 2.4 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGC38277.1 - 1.3e-25 89.0 11.7 6.9e-20 70.6 0.0 3.5 3 0 0 3 3 3 2 CDR ABC transporter ABC2_membrane_3 PF12698.2 EGC38277.1 - 1.2e-13 50.8 60.1 1.5e-08 34.1 13.5 3.9 2 1 1 3 3 3 2 ABC-2 family transporter protein ABC_trans_N PF14510.1 EGC38277.1 - 2.5e-13 49.9 0.1 6.9e-13 48.4 0.0 1.8 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EGC38277.1 - 3.4e-07 29.5 0.0 0.00013 21.2 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_21 PF13304.1 EGC38277.1 - 8e-06 26.0 0.6 0.25 11.2 0.0 3.8 4 0 0 4 4 3 2 AAA domain AAA_29 PF13555.1 EGC38277.1 - 8.6e-06 25.1 0.3 0.0031 17.0 0.1 2.5 2 0 0 2 2 2 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC38277.1 - 2.3e-05 24.5 0.1 0.031 14.4 0.0 2.8 2 1 0 2 2 2 2 AAA domain cobW PF02492.14 EGC38277.1 - 8.9e-05 22.0 0.1 0.0023 17.4 0.0 2.3 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_25 PF13481.1 EGC38277.1 - 9.1e-05 21.9 0.1 0.0017 17.7 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_33 PF13671.1 EGC38277.1 - 0.0018 18.1 0.0 0.2 11.5 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC38277.1 - 0.0079 16.5 0.0 0.82 9.9 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC38277.1 - 0.0083 15.2 0.0 1.7 7.6 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_16 PF13191.1 EGC38277.1 - 0.0087 16.0 0.1 0.68 9.8 0.0 2.4 2 0 0 2 2 2 1 AAA ATPase domain AAA_17 PF13207.1 EGC38277.1 - 0.019 15.7 0.0 0.4 11.5 0.0 2.5 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGC38277.1 - 0.026 14.7 0.4 5.6 7.1 0.1 3.7 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) MMR_HSR1 PF01926.18 EGC38277.1 - 0.028 14.3 0.0 6.3 6.7 0.0 2.5 2 0 0 2 2 2 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGC38277.1 - 0.04 13.8 0.0 0.32 10.9 0.0 2.3 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit Zeta_toxin PF06414.7 EGC38277.1 - 0.049 12.7 0.0 8.1 5.4 0.0 2.4 2 0 0 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EGC38277.1 - 0.056 13.1 0.0 4.1 7.0 0.0 2.7 2 0 0 2 2 2 0 Archaeal ATPase UPF0079 PF02367.12 EGC38277.1 - 0.063 12.9 0.3 0.9 9.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_19 PF13245.1 EGC38277.1 - 0.068 12.9 0.1 14 5.4 0.1 2.6 2 0 0 2 2 2 0 Part of AAA domain AAA_28 PF13521.1 EGC38277.1 - 0.071 13.0 0.3 0.22 11.4 0.1 1.8 2 0 0 2 2 2 0 AAA domain AAA_30 PF13604.1 EGC38277.1 - 0.14 11.7 0.1 4 6.9 0.0 2.3 2 0 0 2 2 2 0 AAA domain ATP-synt_ab PF00006.20 EGC38277.1 - 0.15 11.5 0.0 8.5 5.8 0.0 2.5 2 0 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain PduV-EutP PF10662.4 EGC38277.1 - 0.16 11.4 0.5 1.3 8.4 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation IP_trans PF02121.13 EGC38278.1 - 2.3e-86 289.0 0.7 3e-86 288.7 0.5 1.2 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Coq4 PF05019.8 EGC38279.1 - 1.7e-77 259.2 0.0 2e-77 259.0 0.0 1.1 1 0 0 1 1 1 1 Coenzyme Q (ubiquinone) biosynthesis protein Coq4 ORC5_C PF14630.1 EGC38279.1 - 0.013 14.9 0.0 0.019 14.4 0.0 1.2 1 0 0 1 1 1 0 Origin recognition complex (ORC) subunit 5 C-terminus PH PF00169.24 EGC38280.1 - 9.1e-30 102.9 4.4 1.5e-12 47.6 0.5 3.5 3 0 0 3 3 3 3 PH domain PH_11 PF15413.1 EGC38280.1 - 2.3e-17 63.2 9.4 0.0013 18.9 0.0 5.6 4 1 1 5 5 5 5 Pleckstrin homology domain PH_8 PF15409.1 EGC38280.1 - 0.00023 21.1 7.4 0.024 14.6 0.3 4.5 4 1 0 4 4 4 1 Pleckstrin homology domain PH_9 PF15410.1 EGC38280.1 - 0.0027 17.8 2.7 0.053 13.6 0.0 3.3 3 0 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.1 EGC38280.1 - 0.012 15.5 8.3 0.031 14.1 0.3 4.0 4 1 0 4 4 4 0 PH domain Myosin_TH1 PF06017.8 EGC38280.1 - 0.025 13.8 0.0 4.2 6.6 0.0 2.8 2 0 0 2 2 2 0 Myosin tail RBFA PF02033.13 EGC38280.1 - 0.21 11.6 0.7 1.1 9.2 0.1 2.1 2 0 0 2 2 2 0 Ribosome-binding factor A FGGY_N PF00370.16 EGC38282.1 - 4.7e-44 150.5 0.1 6e-43 146.9 0.1 2.1 1 1 0 1 1 1 1 FGGY family of carbohydrate kinases, N-terminal domain FGGY_C PF02782.11 EGC38282.1 - 2.6e-37 128.4 0.2 7.8e-37 126.8 0.0 1.8 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain YIF1 PF03878.10 EGC38283.1 - 9.1e-67 224.6 7.8 1.3e-66 224.2 5.4 1.2 1 0 0 1 1 1 1 YIF1 Yip1 PF04893.12 EGC38283.1 - 7.3e-06 25.5 1.6 1.7e-05 24.3 1.1 1.6 1 0 0 1 1 1 1 Yip1 domain Cyt-b5 PF00173.23 EGC38284.1 - 5.5e-21 74.1 0.1 1.3e-20 72.9 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain NAD_binding_1 PF00175.16 EGC38284.1 - 3e-16 59.9 0.0 6.4e-16 58.8 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain FAD_binding_6 PF00970.19 EGC38284.1 - 3.6e-15 55.9 0.0 8.3e-15 54.7 0.0 1.6 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_6 PF08030.7 EGC38284.1 - 2.6e-07 30.6 0.0 2.6e-07 30.6 0.0 2.5 2 1 0 3 3 3 1 Ferric reductase NAD binding domain UPF0147 PF03685.8 EGC38285.1 - 0.019 14.8 0.0 0.037 13.9 0.0 1.5 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0147) Pox_A14 PF05767.7 EGC38285.1 - 0.028 14.3 3.9 0.028 14.3 2.7 1.8 2 0 0 2 2 2 0 Poxvirus virion envelope protein A14 Colicin_V PF02674.11 EGC38285.1 - 0.032 14.0 0.6 0.032 14.0 0.4 2.0 2 0 0 2 2 2 0 Colicin V production protein DUF1686 PF07937.6 EGC38285.1 - 0.043 13.4 0.1 0.087 12.4 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1686) DUF4149 PF13664.1 EGC38285.1 - 1.1 9.3 4.5 0.73 9.9 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4149) GATase PF00117.23 EGC38286.1 - 9.9e-18 64.2 0.0 1.3e-17 63.8 0.0 1.1 1 0 0 1 1 1 1 Glutamine amidotransferase class-I Peptidase_C26 PF07722.8 EGC38286.1 - 2e-07 30.6 0.0 7.8e-07 28.7 0.0 1.8 1 1 0 1 1 1 1 Peptidase C26 HTS PF04204.11 EGC38286.1 - 4.3e-07 28.9 0.2 8.3e-07 28.0 0.1 1.6 1 1 0 1 1 1 1 Homoserine O-succinyltransferase GATase_3 PF07685.9 EGC38286.1 - 0.037 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 CobB/CobQ-like glutamine amidotransferase domain DUF830 PF05708.7 EGC38287.1 - 0.074 13.0 0.0 0.32 10.9 0.0 1.9 1 1 0 1 1 1 0 Orthopoxvirus protein of unknown function (DUF830) Ribosomal_L18e PF00828.14 EGC38289.1 - 3.6e-33 114.6 0.1 4.5e-33 114.3 0.0 1.1 1 0 0 1 1 1 1 Ribosomal protein L18e/L15 FNIP PF05725.7 EGC38291.1 - 2.4e-113 369.9 42.9 6.7e-17 61.1 3.1 9.3 6 1 3 10 10 10 10 FNIP Repeat Phage_min_tail PF05939.8 EGC38291.1 - 0.0016 18.3 0.2 13 5.7 0.0 4.8 3 3 3 6 6 6 2 Phage minor tail protein DBD_Tnp_Hermes PF10683.4 EGC38292.1 - 0.1 12.0 0.3 0.87 9.0 0.0 2.4 2 1 0 2 2 2 0 Hermes transposase DNA-binding domain A2L_zn_ribbon PF08792.5 EGC38293.1 - 0.034 13.6 2.4 1 8.9 0.0 2.5 2 0 0 2 2 2 0 A2L zinc ribbon domain Asp_protease PF09668.5 EGC38294.1 - 7e-22 77.3 1.5 2.3e-21 75.6 0.4 2.2 2 0 0 2 2 2 1 Aspartyl protease ubiquitin PF00240.18 EGC38294.1 - 2.7e-11 42.6 2.2 5e-11 41.8 0.4 2.3 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EGC38294.1 - 3.8e-05 23.2 0.2 0.00015 21.4 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EGC38294.1 - 5.1e-05 22.9 0.0 0.00013 21.6 0.0 1.7 1 0 0 1 1 1 1 UBA/TS-N domain UBA_4 PF14555.1 EGC38294.1 - 5.6e-05 22.5 0.0 0.00012 21.5 0.0 1.5 1 0 0 1 1 1 1 UBA-like domain Mucin PF01456.12 EGC38294.1 - 8.3e-05 22.3 6.6 0.00014 21.6 4.6 1.4 1 0 0 1 1 1 1 Mucin-like glycoprotein Rad60-SLD_2 PF13881.1 EGC38294.1 - 0.00027 20.7 1.1 0.00064 19.5 0.7 1.6 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like gag-asp_proteas PF13975.1 EGC38294.1 - 0.00059 19.6 0.0 0.0013 18.5 0.0 1.5 1 0 0 1 1 1 1 gag-polyprotein putative aspartyl protease RVP PF00077.15 EGC38294.1 - 0.00097 19.0 0.6 0.0062 16.4 0.0 2.4 2 0 0 2 2 2 1 Retroviral aspartyl protease Asp_protease_2 PF13650.1 EGC38294.1 - 0.0067 16.9 0.2 0.023 15.2 0.0 2.0 2 0 0 2 2 1 1 Aspartyl protease BAF1_ABF1 PF04684.8 EGC38294.1 - 0.02 13.7 5.6 0.028 13.3 3.9 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Pex14_N PF04695.8 EGC38294.1 - 0.16 12.0 14.5 0.43 10.6 1.8 2.5 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Synaptonemal_3 PF15191.1 EGC38294.1 - 0.57 9.9 2.9 1.8 8.3 0.1 2.7 3 0 0 3 3 2 0 Synaptonemal complex central element protein 3 DUF4557 PF15101.1 EGC38294.1 - 0.91 9.3 18.6 0.61 9.8 5.2 2.6 2 1 1 3 3 3 0 Domain of unknown function (DUF4557) Herpes_BLLF1 PF05109.8 EGC38294.1 - 6.4 4.6 19.2 9 4.1 13.3 1.1 1 0 0 1 1 1 0 Herpes virus major outer envelope glycoprotein (BLLF1) zf-UBR PF02207.15 EGC38295.1 - 1e-12 47.5 17.2 1e-12 47.5 12.0 2.4 2 0 0 2 2 2 1 Putative zinc finger in N-recognin (UBR box) zf-RING_2 PF13639.1 EGC38295.1 - 6e-05 22.7 2.5 6e-05 22.7 1.7 3.6 3 0 0 3 3 3 1 Ring finger domain zf-RING_2 PF13639.1 EGC38296.1 - 1.1e-05 25.1 8.9 1.1e-05 25.1 6.1 6.5 6 1 0 6 6 6 3 Ring finger domain zf-C3HC4_2 PF13923.1 EGC38296.1 - 0.0024 17.8 10.5 0.0024 17.8 7.3 8.4 8 1 0 8 8 8 2 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38296.1 - 0.0061 16.2 9.1 0.0061 16.2 6.3 7.5 7 1 0 7 7 7 2 zinc-RING finger domain WH2 PF02205.15 EGC38297.1 - 7.1e-10 38.1 2.4 1.3e-09 37.3 1.6 1.5 1 0 0 1 1 1 1 WH2 motif AP-5_subunit_s1 PF15001.1 EGC38298.1 - 1.2e-26 93.8 6.6 2.2e-20 73.4 2.3 2.4 1 1 1 2 2 2 2 AP-5 complex subunit sigma-1 APC_CDC26 PF10471.4 EGC38298.1 - 1.1 9.9 14.1 1 10.1 4.6 2.4 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Codanin-1_C PF15296.1 EGC38298.1 - 7.5 6.4 13.1 0.61 9.9 5.0 2.1 2 0 0 2 2 2 0 Codanin-1 C-terminus RPEL PF02755.10 EGC38299.1 - 0.036 13.3 0.4 0.036 13.3 0.3 2.4 2 0 0 2 2 2 0 RPEL repeat TC1 PF15063.1 EGC38299.1 - 0.08 12.4 0.1 0.19 11.2 0.1 1.6 1 0 0 1 1 1 0 Thyroid cancer protein 1 RRM_1 PF00076.17 EGC38300.1 - 4e-20 71.2 0.2 6.4e-10 38.5 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38300.1 - 2.5e-18 65.8 0.1 5.4e-10 39.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38300.1 - 6.3e-15 54.7 0.0 6.9e-08 32.2 0.0 3.1 2 1 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC38300.1 - 0.037 13.7 0.1 0.037 13.7 0.1 2.5 2 0 0 2 2 2 0 Limkain b1 GHL12 PF14882.1 EGC38301.1 - 0.096 12.7 0.2 3.4 7.8 0.0 2.5 2 0 0 2 2 2 0 Hypothetical glycosyl hydrolase 12 FBPase PF00316.15 EGC38302.1 - 5.8e-121 403.2 0.0 6.6e-121 403.0 0.0 1.0 1 0 0 1 1 1 1 Fructose-1-6-bisphosphatase Inositol_P PF00459.20 EGC38302.1 - 0.062 12.5 0.0 0.099 11.9 0.0 1.3 1 0 0 1 1 1 0 Inositol monophosphatase family FAA_hydrolase PF01557.13 EGC38303.1 - 6.3e-57 192.5 0.0 8e-57 192.1 0.0 1.0 1 0 0 1 1 1 1 Fumarylacetoacetate (FAA) hydrolase family ketoacyl-synt PF00109.21 EGC38304.1 - 7.4e-48 163.2 0.1 1.1e-47 162.6 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC38304.1 - 5.5e-31 106.8 0.0 1.2e-30 105.8 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Thiolase_N PF00108.18 EGC38304.1 - 0.00032 19.7 0.0 0.00073 18.5 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Haem_oxygenas_2 PF14518.1 EGC38304.1 - 0.017 15.2 0.0 2.4 8.3 0.0 2.4 2 0 0 2 2 2 0 Iron-containing redox enzyme Thiolase_C PF02803.13 EGC38304.1 - 0.02 14.3 2.1 0.12 11.7 0.0 3.0 3 1 0 3 3 3 0 Thiolase, C-terminal domain WD40 PF00400.27 EGC38305.1 - 1.3e-23 81.9 11.4 2.1e-07 30.5 0.2 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat Nup160 PF11715.3 EGC38305.1 - 8.7e-09 34.0 1.2 2.2e-06 26.1 0.2 2.1 1 1 1 2 2 2 2 Nucleoporin Nup120/160 BBS2_Mid PF14783.1 EGC38305.1 - 0.014 15.2 0.0 0.076 12.7 0.0 2.3 2 1 1 3 3 3 0 Ciliary BBSome complex subunit 2, middle region Pyridox_oxidase PF01243.15 EGC38305.1 - 0.098 12.6 0.0 0.39 10.7 0.0 2.0 1 0 0 1 1 1 0 Pyridoxamine 5'-phosphate oxidase Ycf1 PF05758.7 EGC38305.1 - 7.4 4.1 18.6 0.49 8.0 3.9 2.1 2 0 0 2 2 2 0 Ycf1 NARP1 PF12569.3 EGC38306.1 - 1.5e-125 419.9 26.3 8e-118 394.4 14.4 3.2 2 1 1 3 3 3 2 NMDA receptor-regulated protein 1 TPR_2 PF07719.12 EGC38306.1 - 5.8e-18 63.2 22.3 0.00032 20.3 0.0 8.5 8 0 0 8 8 8 5 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38306.1 - 8.9e-18 64.4 1.1 0.004 17.7 0.0 8.0 7 2 1 8 8 7 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC38306.1 - 1.2e-16 60.0 26.0 4.7e-07 29.3 0.2 7.6 7 3 2 9 9 9 5 TPR repeat TPR_14 PF13428.1 EGC38306.1 - 4.1e-16 58.0 0.1 0.21 12.3 0.0 8.9 8 1 2 10 10 8 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC38306.1 - 7.2e-10 38.6 17.9 0.00026 20.8 0.4 6.8 3 2 3 8 8 8 3 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38306.1 - 2.5e-08 34.1 20.1 0.0066 16.7 1.1 7.6 4 2 3 8 8 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGC38306.1 - 3.6e-08 32.9 12.6 3.6 8.0 0.0 9.2 10 1 0 10 10 9 2 Tetratricopeptide repeat Apc3 PF12895.2 EGC38306.1 - 8.9e-07 28.9 27.8 0.063 13.4 0.2 8.2 5 2 2 8 8 8 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_1 PF00515.23 EGC38306.1 - 1.1e-06 27.9 32.6 0.0018 17.7 0.1 7.6 9 0 0 9 9 9 3 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC38306.1 - 1.2e-06 28.3 12.1 0.0065 16.3 0.0 6.0 7 0 0 7 7 6 2 Fis1 C-terminal tetratricopeptide repeat TPR_7 PF13176.1 EGC38306.1 - 4.1e-06 26.1 7.9 0.079 12.8 0.0 5.6 6 0 0 6 6 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38306.1 - 0.0064 16.8 19.2 1.4 9.5 0.0 9.0 11 0 0 11 11 10 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38306.1 - 0.053 13.3 23.9 2 8.3 0.1 7.2 8 0 0 8 8 8 0 Tetratricopeptide repeat PPR PF01535.15 EGC38306.1 - 0.06 13.3 0.3 2.1 8.4 0.0 3.3 3 0 0 3 3 3 0 PPR repeat PPR_3 PF13812.1 EGC38306.1 - 0.11 12.8 0.0 32 5.1 0.0 3.7 4 0 0 4 4 2 0 Pentatricopeptide repeat domain TPR_10 PF13374.1 EGC38306.1 - 1.1 9.2 4.3 2.9 7.9 0.1 3.8 5 0 0 5 5 4 0 Tetratricopeptide repeat DEAD PF00270.24 EGC38307.1 - 7.7e-43 145.9 0.0 1.6e-42 144.8 0.0 1.6 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38307.1 - 6.8e-23 80.3 0.1 2.4e-22 78.5 0.0 2.0 2 0 0 2 2 2 1 Helicase conserved C-terminal domain DUF4217 PF13959.1 EGC38307.1 - 5e-20 70.8 0.2 1.1e-19 69.7 0.2 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF4217) Helicase_C_2 PF13307.1 EGC38307.1 - 0.015 15.2 0.0 0.092 12.6 0.0 2.4 2 0 0 2 2 2 0 Helicase C-terminal domain ELMO_CED12 PF04727.8 EGC38308.1 - 2.3e-41 141.1 0.1 3.5e-41 140.5 0.1 1.3 1 0 0 1 1 1 1 ELMO/CED-12 family KSR1-SAM PF13543.1 EGC38308.1 - 0.026 14.3 0.9 0.15 11.8 0.0 2.4 2 1 0 2 2 2 0 SAM like domain present in kinase suppressor RAS 1 Dynactin_p62 PF05502.8 EGC38309.1 - 4.7e-46 157.5 24.7 3.6e-45 154.6 17.1 2.1 1 1 0 1 1 1 1 Dynactin p62 family OGG_N PF07934.7 EGC38310.1 - 3.4e-22 78.6 2.3 3.4e-22 78.6 1.6 1.8 2 0 0 2 2 2 1 8-oxoguanine DNA glycosylase, N-terminal domain HhH-GPD PF00730.20 EGC38310.1 - 8.9e-10 38.8 0.0 1.7e-09 37.8 0.0 1.6 1 1 0 1 1 1 1 HhH-GPD superfamily base excision DNA repair protein 2-oxoacid_dh PF00198.18 EGC38311.1 - 3.9e-79 265.1 0.1 5.6e-79 264.6 0.1 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) Biotin_lipoyl PF00364.17 EGC38311.1 - 2.5e-40 135.9 7.2 1.6e-20 72.5 0.3 2.5 2 0 0 2 2 2 2 Biotin-requiring enzyme E3_binding PF02817.12 EGC38311.1 - 9.5e-14 50.7 0.1 2.3e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 e3 binding domain Biotin_lipoyl_2 PF13533.1 EGC38311.1 - 2.3e-08 33.5 0.2 0.00016 21.2 0.0 3.0 3 0 0 3 3 3 2 Biotin-lipoyl like HlyD_3 PF13437.1 EGC38311.1 - 0.00084 19.6 0.7 0.5 10.7 0.1 2.9 2 0 0 2 2 2 1 HlyD family secretion protein HlyD PF00529.15 EGC38311.1 - 0.0013 18.1 2.5 0.11 11.8 0.0 2.7 3 0 0 3 3 3 2 HlyD family secretion protein Peptidase_M23 PF01551.17 EGC38311.1 - 0.0025 17.8 0.2 2.4 8.2 0.0 2.9 2 0 0 2 2 2 2 Peptidase family M23 PYNP_C PF07831.8 EGC38311.1 - 0.0027 17.1 1.4 2.8 7.4 0.0 3.1 3 0 0 3 3 3 2 Pyrimidine nucleoside phosphorylase C-terminal domain HlyD_2 PF12700.2 EGC38311.1 - 0.005 16.0 8.4 0.24 10.5 0.5 3.7 2 2 2 4 4 4 1 HlyD family secretion protein GCV_H PF01597.14 EGC38311.1 - 0.0074 15.9 2.7 2 8.0 0.1 3.2 2 2 1 3 3 3 2 Glycine cleavage H-protein QRPTase_N PF02749.11 EGC38311.1 - 0.012 15.4 0.0 0.91 9.3 0.0 2.6 2 0 0 2 2 2 0 Quinolinate phosphoribosyl transferase, N-terminal domain DUF2118 PF09891.4 EGC38311.1 - 0.029 14.0 0.0 10 5.8 0.0 2.5 2 0 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2118) HTH_Tnp_Tc5 PF03221.11 EGC38311.1 - 0.044 13.6 0.0 0.5 10.2 0.0 2.6 3 0 0 3 3 3 0 Tc5 transposase DNA-binding domain DUF566 PF04484.7 EGC38311.1 - 8.5 5.7 14.9 1.8 8.0 5.8 2.2 2 0 0 2 2 2 0 Family of unknown function (DUF566) ubiquitin PF00240.18 EGC38312.1 - 4.4e-27 93.2 0.1 4.9e-27 93.1 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC38312.1 - 1.5e-17 63.0 0.2 1.7e-17 62.8 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC38312.1 - 1.5e-05 25.1 0.0 5.3e-05 23.4 0.0 1.7 1 1 0 1 1 1 1 Ubiquitin-like domain CTDII PF01556.13 EGC38312.1 - 0.16 11.8 0.5 0.22 11.4 0.3 1.2 1 0 0 1 1 1 0 DnaJ C terminal domain Ala_racemase_N PF01168.15 EGC38313.1 - 1.2e-40 139.4 0.0 1.3e-40 139.2 0.0 1.0 1 0 0 1 1 1 1 Alanine racemase, N-terminal domain HIG_1_N PF04588.8 EGC38315.1 - 9.1e-13 47.7 0.5 1.2e-12 47.3 0.3 1.2 1 0 0 1 1 1 1 Hypoxia induced protein conserved region Hap4_Hap_bind PF10297.4 EGC38315.1 - 0.056 13.3 0.3 0.086 12.7 0.2 1.3 1 0 0 1 1 1 0 Minimal binding motif of Hap4 for binding to Hap2/3/5 Asp PF00026.18 EGC38316.1 - 9.1e-41 140.1 0.7 2e-40 138.9 0.5 1.6 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_N PF14543.1 EGC38316.1 - 9.3e-14 51.7 4.4 1.9e-13 50.6 3.0 1.5 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal TAXi_C PF14541.1 EGC38316.1 - 1.9e-12 47.0 0.0 3.2e-12 46.2 0.0 1.4 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal Big_1 PF02369.11 EGC38316.1 - 0.019 14.8 0.0 0.019 14.8 0.0 3.1 3 0 0 3 3 3 0 Bacterial Ig-like domain (group 1) Epiglycanin_C PF14654.1 EGC38316.1 - 0.026 14.5 0.2 0.11 12.5 0.1 1.9 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region GTP_EFTU PF00009.22 EGC38317.1 - 5.3e-52 175.9 0.2 9.9e-52 175.1 0.2 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain EFG_C PF00679.19 EGC38317.1 - 9.7e-15 54.2 1.0 2.1e-14 53.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor G C-terminus EFG_II PF14492.1 EGC38317.1 - 3.5e-10 39.5 0.0 9.1e-10 38.2 0.0 1.8 1 0 0 1 1 1 1 Elongation Factor G, domain II GTP_EFTU_D2 PF03144.20 EGC38317.1 - 2e-08 34.1 0.1 8.7e-08 32.1 0.0 2.2 2 0 0 2 2 2 1 Elongation factor Tu domain 2 EFG_IV PF03764.13 EGC38317.1 - 1.6e-06 27.7 0.0 0.00047 19.7 0.0 2.9 2 0 0 2 2 2 2 Elongation factor G, domain IV CDC45 PF02724.9 EGC38317.1 - 0.00088 17.4 2.2 0.0019 16.3 1.5 1.5 1 0 0 1 1 1 1 CDC45-like protein ATG27 PF09451.5 EGC38318.1 - 1.9e-23 83.0 0.6 3.3e-23 82.2 0.4 1.3 1 0 0 1 1 1 1 Autophagy-related protein 27 Man-6-P_recep PF02157.10 EGC38318.1 - 4e-10 39.1 2.6 1.6e-09 37.1 1.8 1.8 1 1 0 1 1 1 1 Mannose-6-phosphate receptor Erg28 PF03694.8 EGC38318.1 - 1 9.3 3.1 0.36 10.8 0.3 1.6 2 0 0 2 2 2 0 Erg28 like protein SNAP PF14938.1 EGC38320.1 - 2.7e-24 85.8 12.0 3.7e-24 85.3 8.3 1.1 1 0 0 1 1 1 1 Soluble NSF attachment protein, SNAP TPR_12 PF13424.1 EGC38320.1 - 0.0024 17.7 4.4 0.2 11.5 0.4 3.2 1 1 1 3 3 3 1 Tetratricopeptide repeat HipA_C PF07804.7 EGC38320.1 - 0.11 12.5 1.1 5.3 7.2 0.1 3.0 3 0 0 3 3 3 0 HipA-like C-terminal domain NSF PF02071.15 EGC38320.1 - 1.2 10.0 23.5 5.8 7.9 0.6 6.2 6 0 0 6 6 6 0 Aromatic-di-Alanine (AdAR) repeat TPR_2 PF07719.12 EGC38320.1 - 3.2 7.9 11.5 43 4.3 0.0 5.1 5 2 2 7 7 7 0 Tetratricopeptide repeat Ribosomal_L35Ae PF01247.13 EGC38322.1 - 8.4e-35 118.4 0.1 9.4e-35 118.2 0.0 1.0 1 0 0 1 1 1 1 Ribosomal protein L35Ae 2OG-FeII_Oxy PF03171.15 EGC38323.1 - 0.00028 21.1 0.1 0.00028 21.1 0.1 1.9 2 0 0 2 2 2 1 2OG-Fe(II) oxygenase superfamily CDC45 PF02724.9 EGC38323.1 - 0.0031 15.6 11.0 0.0044 15.1 7.6 1.1 1 0 0 1 1 1 1 CDC45-like protein SDA1 PF05285.7 EGC38323.1 - 0.42 9.8 13.4 0.63 9.2 9.3 1.3 1 0 0 1 1 1 0 SDA1 Sporozoite_P67 PF05642.6 EGC38323.1 - 2.3 5.9 8.2 3.3 5.4 5.7 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen ACBP PF00887.14 EGC38324.1 - 2e-28 97.8 2.5 2.2e-28 97.7 1.8 1.0 1 0 0 1 1 1 1 Acyl CoA binding protein FERM_M PF00373.13 EGC38324.1 - 0.042 14.0 0.2 0.52 10.4 0.1 2.0 1 1 0 1 1 1 0 FERM central domain DUF2975 PF11188.3 EGC38325.1 - 0.0011 18.6 2.6 0.0039 16.9 0.8 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF2975) PGG PF13962.1 EGC38325.1 - 0.016 14.7 5.8 0.047 13.3 1.7 2.5 2 0 0 2 2 2 0 Domain of unknown function DUF4064 PF13273.1 EGC38325.1 - 0.048 13.7 3.0 1.3 9.2 0.1 2.9 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) COPI_assoc PF08507.5 EGC38326.1 - 5.1e-18 65.0 16.1 6.2e-18 64.8 11.2 1.0 1 0 0 1 1 1 1 COPI associated protein DUF2371 PF10177.4 EGC38326.1 - 0.04 13.7 0.1 0.04 13.7 0.1 2.9 2 2 1 3 3 3 0 Uncharacterised conserved protein (DUF2371) Neurensin PF14927.1 EGC38326.1 - 0.76 9.1 16.1 0.52 9.6 2.8 2.9 1 1 1 3 3 3 0 Neurensin DUF308 PF03729.8 EGC38326.1 - 1.7 8.6 29.5 0.6 10.1 12.4 2.3 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) PIG-Y PF15159.1 EGC38326.1 - 3 8.1 8.3 5.2 7.3 0.0 3.1 2 1 1 3 3 3 0 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y FAM70 PF14967.1 EGC38326.1 - 6.7 5.8 7.4 9.2 5.3 5.1 1.3 1 0 0 1 1 1 0 FAM70 protein CBM_20 PF00686.14 EGC38327.1 - 2.2e-16 59.2 0.1 3.7e-16 58.5 0.1 1.3 1 0 0 1 1 1 1 Starch binding domain zf-RING_2 PF13639.1 EGC38327.1 - 6.3e-09 35.5 2.4 2.3e-08 33.7 1.7 2.0 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC38327.1 - 2.5e-08 33.4 0.6 2.5e-08 33.4 0.4 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38327.1 - 3e-08 33.5 2.2 3e-08 33.5 1.5 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EGC38327.1 - 2.3e-07 30.6 0.0 4e-07 29.8 0.0 1.4 1 0 0 1 1 1 1 U-box domain zf-RING_UBOX PF13445.1 EGC38327.1 - 6.5e-07 28.9 1.8 1.6e-06 27.6 1.2 1.6 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EGC38327.1 - 1.2e-06 28.1 0.7 2.7e-06 26.9 0.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38327.1 - 1.9e-06 27.4 3.2 8.4e-06 25.4 2.2 2.1 1 1 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC38327.1 - 8.6e-06 25.7 0.6 8.6e-06 25.7 0.4 2.2 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC38327.1 - 3.2e-05 23.6 2.3 3.2e-05 23.6 1.6 2.3 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-Nse PF11789.3 EGC38327.1 - 0.00072 19.0 1.2 0.0017 17.8 0.1 2.0 2 0 0 2 2 2 1 Zinc-finger of the MIZ type in Nse subunit TIG PF01833.19 EGC38328.1 - 2.8e-09 36.8 52.5 0.00014 21.7 6.6 5.7 5 1 1 6 6 6 4 IPT/TIG domain Qn_am_d_aIII PF09099.5 EGC38328.1 - 0.14 12.4 0.1 3.8 7.8 0.0 2.6 3 0 0 3 3 3 0 Quinohemoprotein amine dehydrogenase, alpha subunit domain III zf-RING_2 PF13639.1 EGC38330.1 - 1.5e-09 37.4 8.2 2.4e-09 36.8 5.7 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38330.1 - 2.6e-07 30.2 5.5 4.3e-07 29.5 3.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38330.1 - 2.9e-07 30.0 10.0 5.7e-07 29.0 6.9 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC38330.1 - 1e-06 28.7 3.3 2.4e-06 27.5 2.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC38330.1 - 1.7e-06 27.9 10.0 3e-06 27.1 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38330.1 - 7.8e-05 22.3 7.7 0.00014 21.5 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain THRAP3_BCLAF1 PF15440.1 EGC38330.1 - 0.00042 19.1 34.3 0.00055 18.7 23.8 1.0 1 0 0 1 1 1 1 THRAP3/BCLAF1 family zf-RING_4 PF14570.1 EGC38330.1 - 0.018 14.6 6.6 0.031 13.8 4.6 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC38330.1 - 0.025 14.4 0.5 0.06 13.1 0.4 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC38330.1 - 0.026 14.3 6.4 0.078 12.8 4.4 1.9 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING DUF1272 PF06906.6 EGC38330.1 - 0.14 12.0 5.8 0.29 11.0 4.0 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 EGC38330.1 - 0.3 10.8 3.2 1 9.1 2.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger WRKY PF03106.10 EGC38331.1 - 9.1e-23 79.8 0.2 1.9e-22 78.8 0.2 1.6 1 0 0 1 1 1 1 WRKY DNA -binding domain KNOX2 PF03791.8 EGC38331.1 - 0.43 9.9 2.4 0.35 10.1 0.4 1.7 2 0 0 2 2 2 0 KNOX2 domain DUF3484 PF11983.3 EGC38331.1 - 8.2 7.3 12.8 22 5.9 8.3 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF3484) WRKY PF03106.10 EGC38332.1 - 1.1e-27 95.5 6.9 1.2e-27 95.4 4.8 1.0 1 0 0 1 1 1 1 WRKY DNA -binding domain DEAD PF00270.24 EGC38333.1 - 1.5e-44 151.4 0.0 6.3e-44 149.4 0.0 1.9 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38333.1 - 1.9e-28 98.1 0.1 3.3e-27 94.1 0.0 2.4 2 0 0 2 2 2 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC38333.1 - 0.0025 17.6 0.0 0.054 13.3 0.0 2.4 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit PWWP PF00855.12 EGC38334.1 - 7.4e-11 42.0 1.3 7.4e-11 42.0 0.9 2.7 2 1 0 2 2 2 1 PWWP domain Fe-S_biosyn PF01521.15 EGC38335.1 - 2.6e-15 56.3 0.2 3.1e-15 56.0 0.1 1.1 1 0 0 1 1 1 1 Iron-sulphur cluster biosynthesis Prefoldin_3 PF13758.1 EGC38335.1 - 0.087 12.6 0.2 0.2 11.4 0.1 1.6 1 1 0 1 1 1 0 Prefoldin subunit DSPc PF00782.15 EGC38336.1 - 3.3e-32 110.8 0.0 3.6e-32 110.7 0.0 1.0 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC38336.1 - 2.1e-06 27.2 0.0 2.2e-06 27.1 0.0 1.1 1 0 0 1 1 1 1 Protein-tyrosine phosphatase DUF442 PF04273.8 EGC38336.1 - 0.0029 17.4 0.0 0.24 11.2 0.0 2.1 2 0 0 2 2 2 1 Putative phosphatase (DUF442) PTPlike_phytase PF14566.1 EGC38336.1 - 0.0094 16.0 0.0 0.012 15.7 0.0 1.2 1 0 0 1 1 1 1 Inositol hexakisphosphate ADH_zinc_N PF00107.21 EGC38336.1 - 0.011 15.2 0.0 0.014 14.9 0.0 1.2 1 0 0 1 1 1 0 Zinc-binding dehydrogenase RE_NgoBV PF09564.5 EGC38336.1 - 0.042 13.0 0.0 0.049 12.8 0.0 1.1 1 0 0 1 1 1 0 NgoBV restriction endonuclease Myotub-related PF06602.9 EGC38336.1 - 0.079 11.7 0.0 0.086 11.5 0.0 1.1 1 0 0 1 1 1 0 Myotubularin-like phosphatase domain DUF4116 PF13475.1 EGC38336.1 - 0.17 11.3 2.3 0.97 8.9 0.4 2.5 2 1 0 2 2 2 0 Domain of unknown function (DUF4116) zf-B_box PF00643.19 EGC38337.1 - 0.00052 19.8 11.8 0.00052 19.8 8.2 1.8 2 0 0 2 2 2 1 B-box zinc finger Sec10 PF07393.6 EGC38338.1 - 3.2e-83 280.1 14.7 7.5e-58 196.3 3.7 2.0 1 1 1 2 2 2 2 Exocyst complex component Sec10 EGF_2 PF07974.8 EGC38339.1 - 0.0062 16.6 10.9 0.013 15.6 7.5 1.5 1 0 0 1 1 1 1 EGF-like domain TFIIA PF03153.8 EGC38340.1 - 1 9.1 23.5 3.8 7.3 14.1 2.0 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit GPCR_chapero_1 PF11904.3 EGC38340.1 - 3.8 6.5 11.9 6.5 5.7 8.3 1.3 1 0 0 1 1 1 0 GPCR-chaperone Ndc1_Nup PF09531.5 EGC38340.1 - 6 5.1 11.2 9 4.5 7.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup MFS_1 PF07690.11 EGC38341.1 - 1.2e-27 96.5 16.0 9.1e-27 93.6 8.4 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_1_like PF12832.2 EGC38341.1 - 2.9e-15 55.8 4.2 2.9e-15 55.8 2.9 2.6 3 0 0 3 3 3 1 MFS_1 like family Nuc_H_symport PF03825.11 EGC38341.1 - 1.1e-10 40.8 27.0 9.7e-10 37.7 7.0 2.1 2 0 0 2 2 2 2 Nucleoside H+ symporter LacY_symp PF01306.14 EGC38341.1 - 1.6e-07 30.2 14.7 1.6e-07 30.2 10.2 2.2 2 0 0 2 2 2 1 LacY proton/sugar symporter MM_CoA_mutase PF01642.17 EGC38343.1 - 1.5e-244 811.9 0.2 1.8e-244 811.6 0.1 1.0 1 0 0 1 1 1 1 Methylmalonyl-CoA mutase B12-binding PF02310.14 EGC38343.1 - 6.3e-17 61.5 0.0 1.7e-16 60.2 0.0 1.7 1 0 0 1 1 1 1 B12 binding domain IF2_N PF04760.10 EGC38343.1 - 0.015 14.8 0.1 5.5 6.7 0.2 2.8 2 0 0 2 2 2 0 Translation initiation factor IF-2, N-terminal region DUF3461 PF11944.3 EGC38343.1 - 0.12 12.1 0.6 0.35 10.7 0.0 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3461) ThiF PF00899.16 EGC38344.1 - 8.7e-40 135.7 0.1 1.7e-39 134.7 0.1 1.5 1 0 0 1 1 1 1 ThiF family UBACT PF02134.16 EGC38344.1 - 6e-25 86.5 0.1 1.3e-24 85.5 0.1 1.6 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGC38344.1 - 9.5e-22 76.1 0.5 2e-21 75.1 0.3 1.6 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGC38344.1 - 9.3e-21 73.7 1.2 2.4e-20 72.4 0.8 1.7 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain NAD_binding_7 PF13241.1 EGC38344.1 - 0.00044 20.4 2.2 0.0017 18.6 0.0 2.6 3 0 0 3 3 3 1 Putative NAD(P)-binding Shikimate_DH PF01488.15 EGC38344.1 - 0.0013 18.8 0.0 0.0028 17.7 0.0 1.6 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase DUF2098 PF09871.4 EGC38345.1 - 0.024 14.5 1.7 0.024 14.5 1.2 2.4 2 1 1 3 3 3 0 Uncharacterized protein conserved in archaea (DUF2098) DUF1127 PF06568.6 EGC38345.1 - 0.67 9.4 2.0 1.1 8.7 1.4 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1127) DUF3439 PF11921.3 EGC38345.1 - 2.7 7.7 13.7 6.5 6.5 9.5 1.7 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Draxin PF15550.1 EGC38345.1 - 9.6 5.7 17.2 76 2.8 12.2 1.8 1 1 0 1 1 1 0 Draxin FNIP PF05725.7 EGC38346.1 - 1.3e-140 457.1 45.7 1.5e-13 50.4 0.1 12.6 6 3 4 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC38346.1 - 0.0026 17.6 27.8 3.1 7.8 0.0 10.7 5 5 9 14 14 14 1 Protein of unknown function (DUF1769) DUF3215 PF11503.3 EGC38346.1 - 0.028 14.0 0.1 4.6 6.9 0.0 4.2 3 1 1 4 4 4 0 Protein of unknown function (DUF3215) zf-RVT PF13966.1 EGC38347.1 - 3.9e-07 30.2 0.6 1.3e-06 28.6 0.4 2.0 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase Peptidase_A22B PF04258.8 EGC38348.1 - 6.4e-48 163.7 19.0 8.6e-48 163.2 13.2 1.1 1 0 0 1 1 1 1 Signal peptide peptidase DUF1673 PF07895.6 EGC38348.1 - 4.3 6.8 20.6 3.6 7.0 12.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1673) DUF1352 PF07086.7 EGC38348.1 - 5 6.7 12.7 0.76 9.3 3.8 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF1352) AcetylCoA_hyd_C PF13336.1 EGC38349.1 - 1.9e-34 118.5 0.0 2.8e-34 118.0 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase C-terminal domain AcetylCoA_hydro PF02550.10 EGC38349.1 - 5.6e-33 114.3 0.0 9.4e-33 113.6 0.0 1.3 1 0 0 1 1 1 1 Acetyl-CoA hydrolase/transferase N-terminal domain CitF PF04223.7 EGC38349.1 - 0.068 11.8 0.0 0.11 11.0 0.0 1.3 1 0 0 1 1 1 0 Citrate lyase, alpha subunit (CitF) TMEM154 PF15102.1 EGC38350.1 - 0.0031 17.2 0.1 0.0062 16.2 0.1 1.5 1 0 0 1 1 1 1 TMEM154 protein family DUF912 PF06024.7 EGC38351.1 - 0.0018 18.3 0.6 0.0046 16.9 0.4 1.7 1 0 0 1 1 1 1 Nucleopolyhedrovirus protein of unknown function (DUF912) TMEM154 PF15102.1 EGC38351.1 - 0.0028 17.3 0.1 0.006 16.2 0.0 1.6 1 0 0 1 1 1 1 TMEM154 protein family MMS19_C PF12460.3 EGC38352.1 - 3e-86 289.7 34.7 3e-86 289.7 24.1 2.9 3 1 1 4 4 4 1 RNAPII transcription regulator C-terminal MMS19_N PF14500.1 EGC38352.1 - 1.9e-78 263.3 14.9 6e-62 209.2 0.4 5.2 4 1 1 5 5 5 3 Dos2-interacting transcription regulator of RNA-Pol-II HEAT_2 PF13646.1 EGC38352.1 - 2.4e-06 27.7 0.0 0.0034 17.6 0.0 3.6 3 1 0 3 3 3 1 HEAT repeats HEAT_EZ PF13513.1 EGC38352.1 - 3.3e-06 27.4 0.2 0.81 10.2 0.0 6.2 6 2 1 7 7 7 1 HEAT-like repeat Vac14_Fab1_bd PF12755.2 EGC38352.1 - 3.9e-05 23.9 4.9 0.014 15.7 0.0 5.1 4 1 0 4 4 4 1 Vacuolar 14 Fab1-binding region HEAT PF02985.17 EGC38352.1 - 0.082 13.0 3.0 46 4.4 0.0 5.7 6 0 0 6 6 6 0 HEAT repeat Spidroin_MaSp PF11260.3 EGC38352.1 - 6.5 6.9 10.5 2.4 8.3 0.1 4.5 5 0 0 5 5 5 0 Major ampullate spidroin 1 and 2 PLAC8 PF04749.12 EGC38353.1 - 5.9e-13 49.3 20.4 7.3e-13 49.0 14.1 1.1 1 0 0 1 1 1 1 PLAC8 family GIDA PF01134.17 EGC38354.1 - 4.7e-152 506.4 0.3 7.1e-152 505.8 0.0 1.4 2 0 0 2 2 2 1 Glucose inhibited division protein A GIDA_assoc_3 PF13932.1 EGC38354.1 - 1.9e-18 66.2 0.0 5e-18 64.9 0.0 1.8 1 0 0 1 1 1 1 GidA associated domain 3 Pyr_redox_2 PF07992.9 EGC38354.1 - 6.6e-06 26.1 0.5 1.8e-05 24.7 0.3 1.7 1 0 0 1 1 1 1 Pyridine nucleotide-disulphide oxidoreductase FAD_oxidored PF12831.2 EGC38354.1 - 0.00031 19.9 0.5 0.00055 19.1 0.4 1.4 1 0 0 1 1 1 1 FAD dependent oxidoreductase FAD_binding_2 PF00890.19 EGC38354.1 - 0.017 13.9 3.2 0.034 12.9 0.9 2.2 2 0 0 2 2 2 0 FAD binding domain AlaDh_PNT_C PF01262.16 EGC38354.1 - 0.024 14.2 0.6 0.044 13.3 0.4 1.4 1 0 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain DAO PF01266.19 EGC38354.1 - 0.033 13.0 2.9 0.26 10.1 0.0 2.2 2 0 0 2 2 2 0 FAD dependent oxidoreductase HI0933_like PF03486.9 EGC38354.1 - 0.069 11.6 3.0 2.3 6.5 0.9 3.1 3 0 0 3 3 3 0 HI0933-like protein Ribosomal_L39 PF00832.15 EGC38355.1 - 2.3e-21 74.9 6.0 2.7e-21 74.7 4.2 1.1 1 0 0 1 1 1 1 Ribosomal L39 protein MgsA_C PF12002.3 EGC38356.1 - 3e-56 189.7 0.1 3e-56 189.7 0.0 2.6 3 0 0 3 3 2 1 MgsA AAA+ ATPase C terminal RuvB_N PF05496.7 EGC38356.1 - 2.3e-19 69.3 0.1 1.4e-17 63.5 0.0 2.2 1 1 1 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA PF00004.24 EGC38356.1 - 3.4e-19 69.3 0.1 7.6e-19 68.2 0.0 1.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_14 PF13173.1 EGC38356.1 - 2.8e-09 36.9 0.0 1.2e-08 34.8 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_5 PF07728.9 EGC38356.1 - 1.3e-08 34.6 0.4 1.1e-07 31.7 0.0 2.6 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) Sigma54_activ_2 PF14532.1 EGC38356.1 - 2.9e-07 30.6 0.0 6.1e-07 29.5 0.0 1.5 1 0 0 1 1 1 1 Sigma-54 interaction domain Sigma54_activat PF00158.21 EGC38356.1 - 4.5e-07 29.4 0.0 0.00045 19.7 0.0 2.4 1 1 0 1 1 1 1 Sigma-54 interaction domain AAA_17 PF13207.1 EGC38356.1 - 1.9e-06 28.6 1.1 5.8e-06 27.1 0.1 2.4 2 1 0 2 2 1 1 AAA domain Mg_chelatase PF01078.16 EGC38356.1 - 2.6e-06 26.7 0.1 0.011 14.8 0.0 2.5 1 1 1 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_16 PF13191.1 EGC38356.1 - 5e-06 26.6 0.0 0.00032 20.7 0.0 2.5 1 1 1 2 2 2 1 AAA ATPase domain Viral_helicase1 PF01443.13 EGC38356.1 - 1.8e-05 24.3 0.0 6.3e-05 22.6 0.0 2.0 1 0 0 1 1 1 1 Viral (Superfamily 1) RNA helicase AAA_22 PF13401.1 EGC38356.1 - 2.3e-05 24.5 0.2 0.00034 20.7 0.2 2.5 1 1 0 1 1 1 1 AAA domain NB-ARC PF00931.17 EGC38356.1 - 7e-05 21.8 0.0 0.0022 16.8 0.0 2.3 1 1 1 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 EGC38356.1 - 0.00011 22.0 1.1 0.0055 16.4 0.0 2.9 1 1 1 2 2 2 1 Archaeal ATPase Zeta_toxin PF06414.7 EGC38356.1 - 0.00034 19.7 0.0 0.0007 18.7 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGC38356.1 - 0.00037 20.8 0.1 0.00037 20.8 0.1 4.2 4 1 0 4 4 3 1 AAA domain MCM PF00493.18 EGC38356.1 - 0.00098 18.0 0.0 0.057 12.2 0.0 2.6 2 0 0 2 2 2 1 MCM2/3/5 family ATP-synt_ab PF00006.20 EGC38356.1 - 0.0021 17.5 0.0 0.0048 16.4 0.0 1.5 1 1 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain AAA_2 PF07724.9 EGC38356.1 - 0.0037 17.1 0.0 0.013 15.3 0.0 2.0 1 0 0 1 1 1 1 AAA domain (Cdc48 subfamily) DUF815 PF05673.8 EGC38356.1 - 0.0042 16.0 0.0 0.013 14.4 0.0 1.8 2 0 0 2 2 2 1 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGC38356.1 - 0.0063 16.8 0.0 0.0063 16.8 0.0 3.4 3 1 1 4 4 2 1 ABC transporter AAA_33 PF13671.1 EGC38356.1 - 0.0082 16.0 0.0 0.025 14.4 0.0 1.9 1 0 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC38356.1 - 0.011 15.6 0.0 0.028 14.4 0.0 1.7 1 0 0 1 1 1 0 AAA domain AAA_24 PF13479.1 EGC38356.1 - 0.015 14.8 0.1 0.015 14.8 0.0 2.7 3 0 0 3 3 2 0 AAA domain NACHT PF05729.7 EGC38356.1 - 0.016 14.9 0.1 0.05 13.2 0.0 1.8 2 0 0 2 2 1 0 NACHT domain IstB_IS21 PF01695.12 EGC38356.1 - 0.016 14.6 0.0 0.04 13.3 0.0 1.6 2 0 0 2 2 1 0 IstB-like ATP binding protein AAA_19 PF13245.1 EGC38356.1 - 0.018 14.8 0.0 0.036 13.8 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_3 PF07726.6 EGC38356.1 - 0.068 12.7 0.0 0.28 10.7 0.0 1.9 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) PAH PF02671.16 EGC38357.1 - 3.1e-05 23.4 0.1 8.9e-05 22.0 0.1 1.8 1 0 0 1 1 1 1 Paired amphipathic helix repeat TINF2_N PF14973.1 EGC38357.1 - 0.035 14.2 2.5 0.047 13.8 1.7 1.3 1 0 0 1 1 1 0 TERF1-interacting nuclear factor 2 N-terminus DUF3713 PF12506.3 EGC38357.1 - 0.093 12.8 3.1 0.11 12.6 2.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3713) Ras PF00071.17 EGC38358.1 - 1.3e-13 50.6 0.7 1.3e-13 50.6 0.5 2.0 2 1 0 2 2 2 1 Ras family Miro PF08477.8 EGC38358.1 - 8.8e-09 35.8 2.4 8.8e-09 35.8 0.1 2.2 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC38358.1 - 1.8e-06 27.3 1.6 2.4e-06 26.9 0.1 2.0 2 1 0 2 2 2 1 ADP-ribosylation factor family AAA_29 PF13555.1 EGC38358.1 - 0.015 14.7 0.0 0.035 13.6 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain DUF2422 PF10337.4 EGC38358.1 - 0.034 12.9 3.0 0.048 12.4 2.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2422) FtsK_SpoIIIE PF01580.13 EGC38358.1 - 0.04 13.3 0.1 0.078 12.4 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family CBP4 PF07960.6 EGC38358.1 - 0.069 12.7 2.6 0.15 11.7 1.8 1.5 1 0 0 1 1 1 0 CBP4 DUF3439 PF11921.3 EGC38358.1 - 0.16 11.7 5.8 0.32 10.7 4.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) zf-RING_2 PF13639.1 EGC38359.1 - 5.6e-10 38.8 9.2 8.5e-10 38.3 6.4 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC38359.1 - 3.1e-08 33.1 11.5 5.6e-08 32.3 8.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC38359.1 - 1.8e-07 30.7 6.7 3.1e-07 29.9 4.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC38359.1 - 5.5e-07 29.6 4.4 1.2e-06 28.5 3.1 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC38359.1 - 4.2e-06 26.6 10.9 6.9e-06 25.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38359.1 - 0.00022 20.8 9.6 0.00037 20.1 6.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC38359.1 - 0.00069 19.4 1.8 0.0012 18.5 1.2 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC38359.1 - 0.0036 16.8 8.8 0.0066 15.9 6.1 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1272 PF06906.6 EGC38359.1 - 0.0073 16.1 5.6 0.015 15.1 3.9 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF1272) zf-C3HC4_4 PF15227.1 EGC38359.1 - 0.012 15.5 9.1 0.04 13.7 6.3 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC38359.1 - 0.33 10.7 3.2 0.68 9.7 2.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC38359.1 - 0.35 10.6 4.0 1.1 8.9 2.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DUF1292 PF06949.6 EGC38359.1 - 0.51 10.7 9.6 0.089 13.1 3.3 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1292) DZR PF12773.2 EGC38359.1 - 0.96 9.3 7.0 3.5 7.5 4.8 1.8 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_3 PF14369.1 EGC38359.1 - 8.6 6.4 9.6 2.5 8.1 4.2 2.0 2 1 0 2 2 1 0 zinc-finger Dicty_REP PF05086.7 EGC38360.1 - 0.13 10.0 13.5 0.15 9.7 9.4 1.0 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein Zip PF02535.17 EGC38360.1 - 0.23 10.4 1.5 0.28 10.1 1.1 1.2 1 0 0 1 1 1 0 ZIP Zinc transporter DUF1510 PF07423.6 EGC38360.1 - 0.65 9.3 10.2 1.6 8.0 7.1 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 EGC38360.1 - 0.83 8.4 9.1 0.96 8.2 6.3 1.2 1 0 0 1 1 1 0 Presenilin Neur_chan_memb PF02932.11 EGC38360.1 - 0.84 9.4 6.2 1.1 9.1 4.3 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Nodulin_late PF07127.6 EGC38360.1 - 0.93 9.6 2.9 0.72 10.0 0.8 1.7 2 0 0 2 2 2 0 Late nodulin protein HCO3_cotransp PF00955.16 EGC38360.1 - 0.93 8.0 4.7 1 7.9 3.2 1.1 1 0 0 1 1 1 0 HCO3- transporter family Kei1 PF08552.6 EGC38360.1 - 0.97 9.0 9.4 9.4 5.8 6.5 1.9 1 1 0 1 1 1 0 Inositolphosphorylceramide synthase subunit Kei1 DUF1183 PF06682.7 EGC38360.1 - 1.4 8.4 9.8 2.7 7.4 6.8 1.6 1 1 0 1 1 1 0 Protein of unknown function (DUF1183) DUF1754 PF08555.5 EGC38360.1 - 2.1 9.0 7.4 3.3 8.3 5.1 1.4 1 1 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF605 PF04652.11 EGC38360.1 - 2.9 7.1 27.0 3.4 6.9 18.7 1.0 1 0 0 1 1 1 0 Vta1 like Lin-8 PF03353.10 EGC38360.1 - 8.8 5.5 14.7 10 5.2 10.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist FNIP PF05725.7 EGC38361.1 - 3.8e-120 391.6 17.0 1.6e-15 56.7 0.0 8.0 3 2 6 10 10 10 10 FNIP Repeat CAF-1_p150 PF11600.3 EGC38362.1 - 0.0076 15.6 25.4 0.0094 15.3 17.6 1.2 1 0 0 1 1 1 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal HTH_23 PF13384.1 EGC38363.1 - 1.8e-06 27.3 0.2 4.2e-06 26.2 0.1 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGC38363.1 - 2.4e-05 24.2 0.5 4.5e-05 23.3 0.3 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EGC38363.1 - 4.7e-05 23.5 0.1 7.5e-05 22.8 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix HTH_38 PF13936.1 EGC38363.1 - 0.00014 21.3 0.2 0.00029 20.3 0.1 1.6 1 0 0 1 1 1 1 Helix-turn-helix domain TrmB PF01978.14 EGC38363.1 - 0.018 14.7 1.0 0.07 12.8 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB PAX PF00292.13 EGC38363.1 - 0.027 14.1 0.0 0.066 12.9 0.0 1.7 1 0 0 1 1 1 0 'Paired box' domain HTH_24 PF13412.1 EGC38363.1 - 0.06 12.7 0.1 0.13 11.7 0.0 1.6 1 0 0 1 1 1 0 Winged helix-turn-helix DNA-binding Phage_pRha PF09669.5 EGC38363.1 - 0.077 13.3 1.2 0.12 12.7 0.3 1.6 1 1 1 2 2 2 0 Phage regulatory protein Rha (Phage_pRha) Fe_dep_repress PF01325.14 EGC38363.1 - 0.12 12.3 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 Iron dependent repressor, N-terminal DNA binding domain Sigma70_r4_2 PF08281.7 EGC38363.1 - 0.12 11.8 0.1 0.21 11.0 0.1 1.3 1 0 0 1 1 1 0 Sigma-70, region 4 HTH_Tnp_Tc3_2 PF01498.13 EGC38363.1 - 0.13 12.3 2.3 0.15 12.1 0.3 1.9 2 0 0 2 2 2 0 Transposase HTH_AsnC-type PF13404.1 EGC38363.1 - 0.13 11.7 0.0 0.25 10.9 0.0 1.4 1 0 0 1 1 1 0 AsnC-type helix-turn-helix domain I_LWEQ PF01608.12 EGC38365.1 - 1.9e-53 180.5 198.4 6.4e-49 165.7 5.3 20.2 7 5 11 20 20 20 11 I/LWEQ domain FERM_M PF00373.13 EGC38365.1 - 6.6e-24 84.4 0.0 6.6e-24 84.4 0.0 3.3 2 1 0 2 2 2 1 FERM central domain FERM_N PF09379.5 EGC38365.1 - 2.9e-23 81.7 0.5 1.1e-18 67.0 0.1 2.9 2 0 0 2 2 2 2 FERM N-terminal domain VHP PF02209.14 EGC38365.1 - 4.7e-15 54.9 0.5 1.2e-14 53.6 0.3 1.8 1 0 0 1 1 1 1 Villin headpiece domain VBS PF08913.5 EGC38365.1 - 0.0028 17.8 3.8 0.0028 17.8 2.7 13.8 10 4 1 11 11 11 6 Vinculin Binding Site PB1 PF00564.19 EGC38365.1 - 0.031 13.9 1.2 2 8.1 0.0 3.6 4 0 0 4 4 4 0 PB1 domain EF-hand_like PF09279.6 EGC38366.1 - 0.024 14.6 0.3 0.063 13.3 0.2 1.7 1 1 0 1 1 1 0 Phosphoinositide-specific phospholipase C, efhand-like PTPS PF01242.14 EGC38366.1 - 0.031 13.9 0.8 0.036 13.7 0.6 1.4 1 1 0 1 1 1 0 6-pyruvoyl tetrahydropterin synthase PIF1 PF05970.9 EGC38366.1 - 0.036 13.0 1.9 0.063 12.2 1.3 1.4 1 1 0 1 1 1 0 PIF1-like helicase STN1_2 PF09170.5 EGC38366.1 - 0.04 13.6 2.6 0.045 13.5 1.8 1.1 1 0 0 1 1 1 0 CST, Suppressor of cdc thirteen homolog, complex subunit STN1 hDGE_amylase PF14701.1 EGC38367.1 - 1.1e-162 541.7 1.0 1.7e-162 541.1 0.7 1.3 1 0 0 1 1 1 1 glucanotransferase domain of human glycogen debranching enzyme GDE_C PF06202.9 EGC38367.1 - 7.1e-107 357.3 0.1 3.1e-106 355.2 0.0 1.9 2 0 0 2 2 2 1 Amylo-alpha-1,6-glucosidase hGDE_central PF14702.1 EGC38367.1 - 8e-76 254.6 0.5 8e-76 254.6 0.4 1.6 2 0 0 2 2 2 1 central domain of human glycogen debranching enzyme hGDE_N PF14699.1 EGC38367.1 - 1.6e-08 34.3 0.1 3.7e-08 33.1 0.1 1.7 1 0 0 1 1 1 1 N-terminal domain from the human glycogen debranching enzyme DUF4038 PF13204.1 EGC38367.1 - 0.0031 16.8 0.1 0.018 14.3 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4038) Alpha-amylase PF00128.19 EGC38367.1 - 0.0042 16.5 0.2 0.0042 16.5 0.1 2.3 3 0 0 3 3 3 1 Alpha amylase, catalytic domain Abhydrolase_4 PF08386.5 EGC38367.1 - 0.064 13.1 0.0 0.15 11.9 0.0 1.5 1 0 0 1 1 1 0 TAP-like protein Transcrip_act PF04949.8 EGC38367.1 - 4.8 6.8 5.9 2.7 7.5 1.3 2.5 3 0 0 3 3 3 0 Transcriptional activator Peptidase_C1 PF00112.18 EGC38368.1 - 0.00092 19.1 0.1 0.002 18.0 0.0 1.6 2 0 0 2 2 2 1 Papain family cysteine protease Peptidase_C1 PF00112.18 EGC38369.1 - 9.4e-06 25.6 0.2 1.9e-05 24.6 0.2 1.5 1 0 0 1 1 1 1 Papain family cysteine protease Peptidase_C1 PF00112.18 EGC38370.1 - 0.13 12.1 0.0 0.23 11.2 0.0 1.5 1 1 0 1 1 1 0 Papain family cysteine protease Proteasom_Rpn13 PF04683.8 EGC38371.1 - 8.9e-06 25.7 0.0 3.3e-05 23.8 0.0 2.0 2 0 0 2 2 2 1 Proteasome complex subunit Rpn13 ubiquitin receptor Telomere_reg-2 PF10193.4 EGC38373.1 - 4.9e-28 97.6 0.3 2.4e-27 95.4 0.0 2.5 2 0 0 2 2 2 1 Telomere length regulation protein HEAT_2 PF13646.1 EGC38373.1 - 0.025 14.8 0.0 2.9 8.2 0.0 3.1 3 0 0 3 3 3 0 HEAT repeats Glyco_hydro_20 PF00728.17 EGC38374.1 - 4.3e-80 269.5 0.0 3.7e-78 263.1 0.0 2.3 1 1 0 1 1 1 1 Glycosyl hydrolase family 20, catalytic domain Glycohydro_20b2 PF14845.1 EGC38374.1 - 2.8e-20 73.2 0.1 7.7e-20 71.8 0.0 1.8 1 0 0 1 1 1 1 beta-acetyl hexosaminidase like Glyco_hydro_20b PF02838.10 EGC38374.1 - 8.7e-06 26.2 0.0 1.7e-05 25.3 0.0 1.5 1 0 0 1 1 1 1 Glycosyl hydrolase family 20, domain 2 ABC_membrane PF00664.18 EGC38375.1 - 3e-62 210.5 43.3 2.1e-34 119.2 13.0 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC38375.1 - 6.3e-46 156.0 6.0 3.3e-30 105.1 0.0 3.4 4 0 0 4 4 3 2 ABC transporter AAA_29 PF13555.1 EGC38375.1 - 1.6e-05 24.2 2.1 0.082 12.4 0.1 2.7 2 0 0 2 2 2 2 P-loop containing region of AAA domain SMC_N PF02463.14 EGC38375.1 - 3.6e-05 23.0 19.2 0.03 13.5 0.0 5.0 4 2 1 6 6 6 3 RecF/RecN/SMC N terminal domain AAA_17 PF13207.1 EGC38375.1 - 0.00037 21.3 0.0 0.54 11.0 0.0 3.1 2 0 0 2 2 2 1 AAA domain Miro PF08477.8 EGC38375.1 - 0.001 19.5 0.7 2.3 8.7 0.0 3.1 2 0 0 2 2 2 2 Miro-like protein FtsK_SpoIIIE PF01580.13 EGC38375.1 - 0.0026 17.2 1.0 0.56 9.6 0.0 2.5 2 0 0 2 2 2 2 FtsK/SpoIIIE family AAA_16 PF13191.1 EGC38375.1 - 0.0045 16.9 2.5 1.4 8.8 0.1 2.7 2 1 0 2 2 2 2 AAA ATPase domain T2SE PF00437.15 EGC38375.1 - 0.0047 15.8 0.1 2.3 7.0 0.0 2.4 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_10 PF12846.2 EGC38375.1 - 0.022 14.1 1.9 4.7 6.5 0.0 3.4 3 0 0 3 3 3 0 AAA-like domain PduV-EutP PF10662.4 EGC38375.1 - 0.029 13.8 2.5 1.6 8.2 0.0 3.0 3 0 0 3 3 3 0 Ethanolamine utilisation - propanediol utilisation AAA_22 PF13401.1 EGC38375.1 - 0.032 14.3 0.4 8.5 6.5 0.0 3.5 3 0 0 3 3 3 0 AAA domain AAA_18 PF13238.1 EGC38375.1 - 0.099 12.9 5.1 10 6.4 0.0 3.9 4 0 0 4 4 3 0 AAA domain AAA_25 PF13481.1 EGC38375.1 - 0.12 11.7 2.4 1.9 7.8 0.0 2.6 3 0 0 3 3 3 0 AAA domain AAA_19 PF13245.1 EGC38375.1 - 0.26 11.0 0.3 6.8 6.5 0.0 2.5 2 0 0 2 2 2 0 Part of AAA domain Frag1 PF10277.4 EGC38376.1 - 4.7e-45 153.6 12.3 5.4e-45 153.5 8.5 1.0 1 0 0 1 1 1 1 Frag1/DRAM/Sfk1 family Tmemb_18A PF09771.4 EGC38376.1 - 0.14 12.1 0.2 0.14 12.1 0.1 1.7 2 0 0 2 2 2 0 Transmembrane protein 188 RRM_1 PF00076.17 EGC38377.1 - 1.4e-21 75.9 0.0 2e-21 75.3 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38377.1 - 6.8e-15 54.8 0.0 9.9e-15 54.2 0.0 1.3 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38377.1 - 1.4e-09 37.6 0.0 2.6e-09 36.7 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC38377.1 - 0.0017 18.1 0.0 0.0026 17.4 0.0 1.4 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Syntaxin_2 PF14523.1 EGC38378.1 - 1.6e-23 82.6 6.4 1.6e-23 82.6 4.4 2.9 2 1 0 2 2 2 1 Syntaxin-like protein SNARE PF05739.14 EGC38378.1 - 1.7e-16 59.6 4.1 1.7e-16 59.6 2.8 3.3 3 1 0 3 3 3 1 SNARE domain DUF3753 PF12575.3 EGC38378.1 - 0.0055 16.4 0.4 0.016 14.9 0.3 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) DUF4064 PF13273.1 EGC38378.1 - 0.0059 16.6 0.9 0.02 14.9 0.6 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF4064) PLDc_N PF13396.1 EGC38378.1 - 0.018 14.7 0.0 0.028 14.0 0.0 1.3 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal LMBR1 PF04791.11 EGC38378.1 - 0.037 12.6 0.0 0.072 11.6 0.0 1.4 1 1 0 1 1 1 0 LMBR1-like membrane protein MCPsignal PF00015.16 EGC38378.1 - 2.1 7.8 13.3 2.6 7.5 5.2 2.3 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Clathrin_lg_ch PF01086.12 EGC38378.1 - 3.5 7.4 11.7 0.15 11.9 4.0 1.7 2 0 0 2 2 2 0 Clathrin light chain Mit_KHE1 PF10173.4 EGC38378.1 - 7.2 6.4 8.5 10 5.9 1.3 2.4 1 1 1 2 2 2 0 Mitochondrial K+-H+ exchange-related DUF1084 PF06454.6 EGC38379.1 - 1.2e-11 44.1 25.2 1.9e-11 43.5 17.5 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) WD40 PF00400.27 EGC38380.1 - 7.5e-27 92.1 7.9 2.7e-07 30.2 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGC38380.1 - 5.6e-05 21.4 0.1 0.013 13.7 0.0 3.3 2 1 0 2 2 2 1 Nucleoporin Nup120/160 PQQ_2 PF13360.1 EGC38380.1 - 0.0031 17.0 0.0 0.005 16.3 0.0 1.3 1 0 0 1 1 1 1 PQQ-like domain DUF1900 PF08954.6 EGC38380.1 - 0.014 14.9 0.0 3.8 7.0 0.0 3.2 2 1 1 3 3 3 0 Domain of unknown function (DUF1900) HOOK PF05622.7 EGC38381.1 - 0.03 12.1 10.8 0.049 11.4 7.5 1.4 1 1 0 1 1 1 0 HOOK protein ERM PF00769.14 EGC38381.1 - 0.037 13.5 12.7 0.044 13.3 8.8 1.1 1 0 0 1 1 1 0 Ezrin/radixin/moesin family Apt1 PF10351.4 EGC38381.1 - 0.073 11.9 8.1 0.082 11.7 5.6 1.0 1 0 0 1 1 1 0 Golgi-body localisation protein domain AAA_13 PF13166.1 EGC38381.1 - 0.086 11.2 9.2 0.092 11.1 6.4 1.1 1 0 0 1 1 1 0 AAA domain V_ATPase_I PF01496.14 EGC38381.1 - 0.088 10.6 7.7 0.093 10.5 5.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family DUF2203 PF09969.4 EGC38381.1 - 0.11 12.7 4.0 0.17 12.1 2.8 1.4 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2203) DUF3310 PF11753.3 EGC38381.1 - 0.14 12.1 1.5 2.5 8.1 0.6 2.4 2 1 0 2 2 2 0 Protein of unknwon function (DUF3310) TEX12 PF15219.1 EGC38381.1 - 0.15 12.0 3.0 2.5 8.1 0.0 2.3 1 1 1 2 2 2 0 Testis-expressed 12 TarH PF02203.10 EGC38381.1 - 0.19 11.5 2.5 0.25 11.1 1.6 1.3 1 1 0 1 1 1 0 Tar ligand binding domain homologue DIRP PF06584.8 EGC38381.1 - 0.4 10.5 3.2 0.77 9.6 2.1 1.6 1 1 0 1 1 1 0 DIRP DUF4208 PF13907.1 EGC38381.1 - 0.56 10.4 6.8 4.1 7.6 0.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4208) DUF342 PF03961.8 EGC38381.1 - 0.62 8.4 10.8 0.71 8.2 7.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Hrs_helical PF12210.3 EGC38381.1 - 0.88 9.8 9.5 0.27 11.4 1.1 2.3 1 1 1 2 2 2 0 Hepatocyte growth factor-regulated tyrosine kinase substrate DUF2115 PF09888.4 EGC38381.1 - 0.9 9.6 4.8 1.1 9.3 3.3 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) FCH PF00611.18 EGC38381.1 - 1.1 9.4 7.3 6.6 7.0 0.4 2.6 1 1 1 2 2 2 0 Fes/CIP4, and EFC/F-BAR homology domain TMF_DNA_bd PF12329.3 EGC38381.1 - 1.7 8.4 18.5 2.6 7.9 9.5 3.1 1 1 1 2 2 2 0 TATA element modulatory factor 1 DNA binding TMPIT PF07851.8 EGC38381.1 - 2.2 7.2 5.3 2.4 7.1 3.6 1.1 1 0 0 1 1 1 0 TMPIT-like protein Atg14 PF10186.4 EGC38381.1 - 2.3 7.1 10.5 2.6 6.9 7.3 1.2 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 Spc24 PF08286.6 EGC38381.1 - 2.3 7.9 11.1 3.3 7.4 5.6 2.1 1 1 1 2 2 2 0 Spc24 subunit of Ndc80 DUF2458 PF10454.4 EGC38381.1 - 3.1 7.6 11.6 0.67 9.8 5.1 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF2458) APG6 PF04111.7 EGC38381.1 - 4.6 6.2 11.6 5.6 5.9 8.0 1.1 1 0 0 1 1 1 0 Autophagy protein Apg6 TMF_TATA_bd PF12325.3 EGC38381.1 - 7.9 6.2 17.1 3.9 7.2 9.3 2.1 2 1 0 2 2 2 0 TATA element modulatory factor 1 TATA binding Atg8 PF02991.11 EGC38382.1 - 3.3e-34 116.9 0.2 4e-34 116.7 0.1 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like APG12 PF04110.8 EGC38382.1 - 0.00013 22.1 0.1 0.00019 21.5 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 DUF2972 PF11186.3 EGC38382.1 - 0.15 11.8 2.6 0.17 11.7 1.8 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2972) Arm PF00514.18 EGC38383.1 - 0.0019 17.9 2.1 11 6.0 0.0 5.6 7 0 0 7 7 7 2 Armadillo/beta-catenin-like repeat Cut8_M PF14483.1 EGC38383.1 - 0.017 14.9 0.2 0.088 12.6 0.1 2.4 2 0 0 2 2 2 0 Cut8 dimerisation domain RTTN_N PF14726.1 EGC38383.1 - 0.053 14.0 2.6 18 5.9 0.0 4.0 4 0 0 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning FNIP PF05725.7 EGC38386.1 - 2.4e-163 529.9 50.3 6.9e-17 61.1 0.8 12.6 10 1 2 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC38386.1 - 0.0083 16.0 36.4 4.2 7.4 0.2 13.1 6 2 12 18 18 18 4 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC38386.1 - 0.013 15.2 6.3 1.5 8.5 0.1 5.2 2 2 3 5 5 5 0 Leucine rich repeats (6 copies) DUF912 PF06024.7 EGC38388.1 - 0.032 14.2 0.5 0.032 14.2 0.4 1.8 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tox-MPTase3 PF15639.1 EGC38388.1 - 0.069 12.9 0.1 0.14 11.8 0.0 1.6 1 0 0 1 1 1 0 Metallopeptidase toxin 3 FNIP PF05725.7 EGC38390.1 - 4.4e-131 426.6 46.8 4.2e-15 55.4 0.1 11.0 10 1 1 11 11 11 10 FNIP Repeat PAG PF15347.1 EGC38391.1 - 0.12 11.4 0.1 0.12 11.4 0.0 1.1 1 0 0 1 1 1 0 Phosphoprotein associated with glycosphingolipid-enriched TAP_C PF03943.8 EGC38392.1 - 3e-07 29.7 1.1 5.1e-07 29.0 0.8 1.4 1 0 0 1 1 1 1 TAP C-terminal domain PS_Dcarbxylase PF02666.10 EGC38394.1 - 1.6 7.9 5.4 0.26 10.5 0.3 1.8 1 1 1 2 2 2 0 Phosphatidylserine decarboxylase FA_hydroxylase PF04116.8 EGC38396.1 - 1.6e-18 67.1 11.0 1.6e-18 67.1 7.6 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily FA_hydroxylase PF04116.8 EGC38397.1 - 1.7e-16 60.5 8.7 1.7e-16 60.5 6.0 1.8 2 1 0 2 2 2 1 Fatty acid hydroxylase superfamily DUF3816 PF12822.2 EGC38397.1 - 0.5 10.2 7.2 0.94 9.3 5.0 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) hEGF PF12661.2 EGC38399.1 - 0.00086 19.2 14.4 0.0059 16.6 1.2 3.7 3 0 0 3 3 3 2 Human growth factor-like EGF PQQ_3 PF13570.1 EGC38399.1 - 0.0019 18.3 1.2 1.1 9.6 0.0 4.0 4 0 0 4 4 4 1 PQQ-like domain Laminin_EGF PF00053.19 EGC38399.1 - 0.0049 16.7 2.0 0.0049 16.7 1.4 3.1 3 0 0 3 3 3 1 Laminin EGF-like (Domains III and V) cEGF PF12662.2 EGC38399.1 - 0.025 14.2 8.4 0.37 10.4 0.3 3.1 2 0 0 2 2 2 0 Complement Clr-like EGF-like EGF PF00008.22 EGC38399.1 - 0.39 10.7 11.9 0.45 10.5 0.1 3.7 2 1 0 2 2 2 0 EGF-like domain FNIP PF05725.7 EGC38400.1 - 3.6e-21 74.8 58.6 4.9e-08 32.7 0.2 10.2 8 2 1 9 9 9 6 FNIP Repeat LRR_7 PF13504.1 EGC38400.1 - 2.8 8.5 9.2 85 4.0 0.0 6.4 7 0 0 7 7 7 0 Leucine rich repeat Lactamase_B_2 PF12706.2 EGC38401.1 - 5.7e-38 130.4 1.5 7.6e-38 130.0 0.5 1.6 2 0 0 2 2 2 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGC38401.1 - 3.6e-15 56.0 0.0 4.8e-15 55.6 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGC38401.1 - 0.00015 21.5 0.1 0.00047 19.8 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_transf_43 PF03360.11 EGC38401.1 - 0.001 18.6 0.0 0.0016 18.0 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 43 FNIP PF05725.7 EGC38402.1 - 2.1e-56 187.5 22.4 1.9e-11 43.7 0.9 6.8 4 1 3 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC38402.1 - 0.0093 15.8 6.5 6.2 6.8 0.0 4.6 5 1 1 6 6 6 2 Protein of unknown function (DUF1769) zf-C3HC4_3 PF13920.1 EGC38403.1 - 1.7e-08 34.0 8.4 2.8e-08 33.3 5.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38403.1 - 3.8e-08 32.8 9.5 8.7e-08 31.7 6.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC38403.1 - 1.2e-07 31.4 9.5 2e-07 30.7 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC38403.1 - 3.7e-06 26.9 5.7 8.5e-06 25.7 3.9 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC38403.1 - 5.6e-06 26.2 9.9 9.9e-06 25.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38403.1 - 0.0022 17.7 10.0 0.0041 16.8 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain DUF1183 PF06682.7 EGC38403.1 - 0.0098 15.5 5.5 0.022 14.3 3.8 1.7 1 0 0 1 1 1 1 Protein of unknown function (DUF1183) zf-C3HC4_4 PF15227.1 EGC38403.1 - 0.011 15.5 9.6 0.052 13.4 6.5 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-RING_UBOX PF13445.1 EGC38403.1 - 0.032 13.9 3.2 0.1 12.2 2.2 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EGC38403.1 - 0.2 11.5 7.1 2.7 7.8 4.9 2.3 1 1 1 2 2 2 0 Double zinc ribbon zf-RING_4 PF14570.1 EGC38403.1 - 0.54 9.8 11.1 3.9 7.1 7.6 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain Defensin_1 PF00323.14 EGC38404.1 - 0.17 12.2 0.7 0.93 9.9 0.1 2.0 2 0 0 2 2 2 0 Mammalian defensin MGC-24 PF05283.6 EGC38405.1 - 0.24 11.1 14.3 0.38 10.5 9.9 1.3 1 0 0 1 1 1 0 Multi-glycosylated core protein 24 (MGC-24) Pneumo_att_G PF05539.6 EGC38405.1 - 6.2 6.0 14.6 9.2 5.5 10.1 1.2 1 0 0 1 1 1 0 Pneumovirinae attachment membrane glycoprotein G DGF-1_4 PF11024.3 EGC38405.1 - 9.2 6.7 20.8 16 5.9 14.4 1.3 1 0 0 1 1 1 0 Dispersed gene family protein 1 of Trypanosoma cruzi region 4 ketoacyl-synt PF00109.21 EGC38406.1 - 8.7e-60 202.3 0.0 1.3e-59 201.7 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38406.1 - 8.2e-43 146.9 0.0 1.4e-42 146.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38406.1 - 1.1e-31 109.1 0.0 2.1e-31 108.2 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain PS-DH PF14765.1 EGC38406.1 - 5.5e-20 71.7 0.0 8.3e-20 71.1 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EGC38406.1 - 3e-19 69.3 2.5 3.8e-19 68.9 0.0 2.7 2 0 0 2 2 1 1 Methyltransferase domain KR PF08659.5 EGC38406.1 - 2.3e-18 66.5 0.0 5.5e-13 48.9 0.1 2.9 2 1 1 3 3 3 2 KR domain adh_short PF00106.20 EGC38406.1 - 2.4e-09 37.3 0.0 9.9e-07 28.8 0.0 2.7 2 1 0 2 2 1 1 short chain dehydrogenase ADH_N PF08240.7 EGC38406.1 - 9e-09 35.0 0.0 2.4e-08 33.6 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC38406.1 - 1.9e-08 34.1 0.0 6.2e-08 32.5 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38406.1 - 8.2e-08 32.6 0.0 3.9e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC38406.1 - 5e-07 30.6 0.0 1.2e-06 29.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGC38406.1 - 0.0002 21.9 0.1 0.004 17.7 0.0 3.2 4 0 0 4 4 3 1 Methyltransferase domain PP-binding PF00550.20 EGC38406.1 - 0.00051 20.2 0.0 0.0013 18.8 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC38406.1 - 0.036 13.0 0.0 0.066 12.1 0.0 1.3 1 0 0 1 1 1 0 Thiolase, N-terminal domain FNIP PF05725.7 EGC38407.1 - 2.3e-42 142.6 88.3 1.7e-11 43.9 5.1 12.2 9 2 3 12 12 12 11 FNIP Repeat DDE_Tnp_4 PF13359.1 EGC38408.1 - 9.1e-21 74.0 0.1 2e-20 72.9 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF1943 PF09172.6 EGC38408.1 - 0.068 12.0 0.2 0.2 10.4 0.0 1.7 2 0 0 2 2 2 0 Domain of unknown function (DUF1943) DUF963 PF06131.6 EGC38408.1 - 0.21 10.8 8.5 0.036 13.3 2.6 2.3 2 1 0 2 2 2 0 Schizosaccharomyces pombe repeat of unknown function (DUF963) DUF2946 PF11162.3 EGC38408.1 - 0.27 11.4 6.9 0.53 10.5 4.8 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2946) TFIIIC_sub6 PF10419.4 EGC38409.1 - 0.027 13.9 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 TFIIIC subunit CHORD PF04968.7 EGC38410.1 - 9.1e-48 160.3 29.3 4.8e-24 84.3 6.1 2.4 2 0 0 2 2 2 2 CHORD CS PF04969.11 EGC38410.1 - 8.7e-12 45.4 2.5 1.7e-11 44.4 1.7 1.5 1 0 0 1 1 1 1 CS domain Secretin_N_2 PF07655.8 EGC38411.1 - 0.64 10.4 24.0 2.1 8.7 16.6 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain Phytochelatin PF05023.9 EGC38412.1 - 9e-87 289.5 0.0 1.5e-86 288.7 0.0 1.4 1 0 0 1 1 1 1 Phytochelatin synthase Peptidase_C39_2 PF13529.1 EGC38412.1 - 0.00015 22.1 2.6 0.35 11.2 0.0 3.4 3 0 0 3 3 3 1 Peptidase_C39 like family Phytochelatin_C PF09328.5 EGC38412.1 - 0.0024 17.4 0.0 0.071 12.5 0.0 3.0 4 0 0 4 4 4 1 Domain of unknown function (DUF1984) Peptidase_C39 PF03412.10 EGC38412.1 - 0.051 13.3 0.0 4.5 7.0 0.0 2.5 2 0 0 2 2 2 0 Peptidase C39 family FNIP PF05725.7 EGC38413.1 - 1.1e-94 310.1 81.1 8.5e-12 44.8 0.4 13.3 9 1 5 15 15 15 14 FNIP Repeat DUF1769 PF08588.5 EGC38413.1 - 8.6e-08 32.0 21.2 0.38 10.7 0.1 8.3 5 3 5 10 10 10 4 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC38413.1 - 7.4e-06 25.6 16.9 0.082 12.6 0.1 5.6 2 1 3 6 6 6 3 Leucine rich repeats (6 copies) SMC_N PF02463.14 EGC38414.1 - 5.4e-26 91.1 3.9 9.2e-25 87.1 2.7 2.4 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_23 PF13476.1 EGC38414.1 - 6.5e-08 33.1 52.3 6.5e-08 33.1 36.3 6.2 3 2 1 4 4 4 1 AAA domain AAA_29 PF13555.1 EGC38414.1 - 2.7e-05 23.6 0.0 5.5e-05 22.6 0.0 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_21 PF13304.1 EGC38414.1 - 0.00095 19.2 15.4 0.00095 19.2 10.7 4.7 1 1 1 3 3 3 2 AAA domain SMC_hinge PF06470.8 EGC38414.1 - 0.0024 17.8 0.1 0.6 10.0 0.0 3.2 2 0 0 2 2 2 1 SMC proteins Flexible Hinge Domain DUF869 PF05911.6 EGC38414.1 - 0.11 10.7 63.1 0.19 9.9 16.8 2.3 2 0 0 2 2 2 0 Plant protein of unknown function (DUF869) Reo_sigmaC PF04582.7 EGC38414.1 - 0.18 10.9 8.1 0.084 12.0 0.7 3.2 3 1 0 3 3 3 0 Reovirus sigma C capsid protein ABC_tran PF00005.22 EGC38414.1 - 0.23 11.7 0.0 0.23 11.7 0.0 5.6 3 2 1 4 4 4 0 ABC transporter AAA_13 PF13166.1 EGC38414.1 - 0.4 9.0 0.0 0.4 9.0 0.0 5.5 3 2 2 5 5 5 0 AAA domain Aminotran_5 PF00266.14 EGC38418.1 - 0.11 11.1 0.0 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Aminotransferase class-V zf-C3HC4_3 PF13920.1 EGC38419.1 - 3.4e-09 36.2 7.9 5.7e-09 35.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38419.1 - 4.2e-08 32.7 9.5 9e-08 31.6 6.6 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC38419.1 - 1.2e-07 31.4 9.5 2e-07 30.6 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC38419.1 - 4.1e-06 26.7 5.7 8.8e-06 25.7 3.9 1.5 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC38419.1 - 5.7e-06 26.2 9.9 1e-05 25.4 6.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38419.1 - 0.00077 19.1 9.3 0.0014 18.3 6.4 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC38419.1 - 0.013 15.4 9.8 0.064 13.1 6.6 2.2 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING DUF1183 PF06682.7 EGC38419.1 - 0.016 14.8 1.7 0.033 13.7 1.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) zf-RING_UBOX PF13445.1 EGC38419.1 - 0.033 13.8 3.2 0.11 12.2 2.2 1.9 1 0 0 1 1 1 0 RING-type zinc-finger OppC_N PF12911.2 EGC38419.1 - 0.034 13.5 0.2 0.081 12.3 0.1 1.7 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Pox_P21 PF05313.7 EGC38419.1 - 0.15 11.2 2.5 0.17 11.1 0.7 1.9 1 1 1 2 2 2 0 Poxvirus P21 membrane protein DZR PF12773.2 EGC38419.1 - 0.21 11.4 7.5 3.2 7.6 4.8 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-Apc11 PF12861.2 EGC38419.1 - 0.35 10.7 5.0 0.74 9.6 3.4 1.5 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC38419.1 - 0.49 10.0 11.1 3.2 7.3 7.6 2.2 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain FNIP PF05725.7 EGC38420.1 - 7e-85 278.7 63.6 1.1e-13 50.9 2.5 10.2 7 3 3 11 11 11 10 FNIP Repeat LRR_5 PF13306.1 EGC38420.1 - 1.6e-08 34.3 3.1 0.17 11.5 0.0 4.2 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC38420.1 - 3e-06 27.0 17.0 1.3 9.0 0.0 8.9 5 2 4 10 10 10 3 Protein of unknown function (DUF1769) FA_hydroxylase PF04116.8 EGC38421.1 - 5e-17 62.3 14.0 5e-17 62.3 9.7 1.9 2 1 1 3 3 3 1 Fatty acid hydroxylase superfamily DUF788 PF05620.6 EGC38421.1 - 3.3 7.5 8.5 0.17 11.7 0.2 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF788) FNIP PF05725.7 EGC38422.1 - 7.8e-74 243.4 30.3 1.2e-14 53.9 0.1 8.0 3 1 4 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC38422.1 - 6.9e-10 38.7 14.0 0.47 10.4 0.0 9.5 4 2 7 11 11 11 5 Protein of unknown function (DUF1769) Pkinase_Tyr PF07714.12 EGC38423.1 - 6e-35 120.5 0.0 7.9e-35 120.1 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC38423.1 - 1.2e-30 106.5 0.0 1.7e-30 106.0 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Kinase-like PF14531.1 EGC38423.1 - 0.06 12.2 0.0 0.09 11.7 0.0 1.2 1 0 0 1 1 1 0 Kinase-like EST1 PF10374.4 EGC38424.1 - 0.048 13.6 6.0 0.18 11.7 4.2 2.1 1 1 0 1 1 1 0 Telomerase activating protein Est1 UCR_hinge PF02320.11 EGC38425.1 - 0.043 13.7 0.0 0.043 13.7 0.0 1.7 2 0 0 2 2 2 0 Ubiquinol-cytochrome C reductase hinge protein Pinin_SDK_memA PF04696.8 EGC38425.1 - 0.099 12.2 22.1 0.022 14.3 10.4 2.1 2 0 0 2 2 2 0 pinin/SDK/memA/ protein conserved region LpxB PF02684.10 EGC38425.1 - 0.23 10.0 4.9 0.27 9.8 3.4 1.1 1 0 0 1 1 1 0 Lipid-A-disaccharide synthetase DUF4337 PF14235.1 EGC38425.1 - 0.32 10.8 8.4 0.39 10.5 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4337) DDHD PF02862.12 EGC38425.1 - 3.1 7.5 7.8 3.5 7.3 5.4 1.1 1 0 0 1 1 1 0 DDHD domain FmdE PF02663.9 EGC38425.1 - 3.1 7.6 5.8 2.9 7.8 3.4 1.3 1 1 0 1 1 1 0 FmdE, Molybdenum formylmethanofuran dehydrogenase operon RNase_H2-Ydr279 PF09468.5 EGC38425.1 - 3.2 6.8 11.8 4.1 6.5 8.2 1.1 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAA_11 PF13086.1 EGC38425.1 - 3.3 7.2 8.7 3.6 7.0 6.0 1.1 1 0 0 1 1 1 0 AAA domain IncA PF04156.9 EGC38425.1 - 5.2 6.6 6.8 7.6 6.0 4.7 1.3 1 0 0 1 1 1 0 IncA protein Herpes_DNAp_acc PF04929.7 EGC38425.1 - 6.6 5.5 9.4 6.9 5.5 6.5 1.0 1 0 0 1 1 1 0 Herpes DNA replication accessory factor Tnp_P_element PF12017.3 EGC38425.1 - 7.1 5.7 8.3 7.1 5.7 5.3 1.3 1 1 0 1 1 1 0 Transposase protein OTU PF02338.14 EGC38426.1 - 4.9e-12 46.4 0.0 4.9e-12 46.4 0.0 3.0 2 1 0 2 2 2 1 OTU-like cysteine protease Helicase_C PF00271.26 EGC38427.1 - 0.055 13.3 0.0 0.13 12.1 0.0 1.6 1 0 0 1 1 1 0 Helicase conserved C-terminal domain EGF_2 PF07974.8 EGC38428.1 - 0.045 13.9 11.3 0.019 15.1 6.0 1.7 2 0 0 2 2 2 0 EGF-like domain Mito_carr PF00153.22 EGC38430.1 - 2.7e-67 222.5 3.7 2.3e-24 84.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein zf-AN1 PF01428.11 EGC38431.1 - 3.8e-20 71.4 19.1 1.2e-11 44.2 5.9 2.7 2 0 0 2 2 2 2 AN1-like Zinc finger UBX PF00789.15 EGC38431.1 - 1.8e-06 27.9 0.0 5.5e-06 26.3 0.0 1.8 1 0 0 1 1 1 1 UBX domain Transp_Tc5_C PF04236.10 EGC38431.1 - 0.029 14.5 5.2 0.029 14.5 3.6 2.7 3 0 0 3 3 3 0 Tc5 transposase C-terminal domain Glyco_hydro_26 PF02156.10 EGC38431.1 - 0.065 12.6 0.1 3.4 7.0 0.1 2.1 2 0 0 2 2 2 0 Glycosyl hydrolase family 26 Ribosomal_S4 PF00163.14 EGC38431.1 - 0.089 13.1 0.3 0.18 12.2 0.2 1.5 1 0 0 1 1 1 0 Ribosomal protein S4/S9 N-terminal domain FA_desaturase PF00487.19 EGC38433.1 - 8.5e-23 81.0 37.1 3.5e-18 65.9 14.1 3.9 3 1 0 3 3 3 2 Fatty acid desaturase Cyt-b5 PF00173.23 EGC38433.1 - 7.2e-14 51.3 0.0 1.7e-13 50.1 0.0 1.7 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain RSN1_TM PF13967.1 EGC38433.1 - 3.7 7.0 12.8 0.38 10.3 1.6 3.6 3 1 0 3 3 3 0 Late exocytosis, associated with Golgi transport Chitin_bind_3 PF03067.10 EGC38434.1 - 5.7e-46 157.0 0.1 6.5e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Chitin binding domain Ribosom_S12_S23 PF00164.20 EGC38435.1 - 4.8e-37 126.0 0.9 5.5e-37 125.8 0.6 1.1 1 0 0 1 1 1 1 Ribosomal protein S12/S23 stn_TNFRSF12A PF12191.3 EGC38436.1 - 0.0032 17.4 0.0 0.0072 16.3 0.0 1.6 1 0 0 1 1 1 1 Tumour necrosis factor receptor stn_TNFRSF12A_TNFR domain Amnionless PF14828.1 EGC38436.1 - 0.0046 15.5 0.1 0.16 10.4 0.0 2.3 2 0 0 2 2 2 2 Amnionless Sigma_reg_N PF13800.1 EGC38436.1 - 0.81 9.7 7.9 0.09 12.8 1.1 2.5 2 0 0 2 2 2 0 Sigma factor regulator N-terminal 2TM PF13239.1 EGC38436.1 - 4.3 7.4 6.4 8.2 6.5 0.7 2.5 2 0 0 2 2 2 0 2TM domain MFMR PF07777.6 EGC38437.1 - 0.089 12.7 2.4 0.2 11.5 1.7 1.5 1 0 0 1 1 1 0 G-box binding protein MFMR HSP20 PF00011.16 EGC38438.1 - 2.5e-14 52.9 1.5 1.3e-06 28.1 0.0 2.2 1 1 0 2 2 2 2 Hsp20/alpha crystallin family CS PF04969.11 EGC38438.1 - 0.052 14.0 1.9 0.18 12.3 0.3 2.3 2 0 0 2 2 2 0 CS domain DDE_Tnp_1_6 PF13751.1 EGC38438.1 - 0.11 12.4 0.1 0.23 11.4 0.0 1.4 1 1 0 1 1 1 0 Transposase DDE domain NAD_binding_6 PF08030.7 EGC38438.1 - 1.5 8.7 5.4 1.9 8.3 3.6 1.4 1 1 0 1 1 1 0 Ferric reductase NAD binding domain Coiled PF05710.7 EGC38440.1 - 1.2e-16 60.9 18.8 1.3e-16 60.8 13.1 1.0 1 0 0 1 1 1 1 Coiled coil Chlorosome_CsmC PF11098.3 EGC38440.1 - 0.74 9.5 4.0 1.3 8.6 2.8 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF1517 PF07466.6 EGC38440.1 - 1.3 7.9 3.9 1.5 7.7 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Bacteriocin_IIc PF10439.4 EGC38440.1 - 1.5 8.9 12.6 2.2 8.4 8.7 1.4 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EGC38440.1 - 7.3 6.2 11.7 12 5.5 8.1 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Coiled PF05710.7 EGC38441.1 - 6.8e-07 29.6 18.7 7.8e-07 29.4 13.0 1.0 1 0 0 1 1 1 1 Coiled coil Proteasom_Rpn13 PF04683.8 EGC38442.1 - 3.2e-23 81.5 0.0 5.6e-23 80.8 0.0 1.4 1 0 0 1 1 1 1 Proteasome complex subunit Rpn13 ubiquitin receptor MoaE PF02391.12 EGC38443.1 - 1.6e-31 108.5 0.0 1.9e-31 108.2 0.0 1.1 1 0 0 1 1 1 1 MoaE protein AAA_8 PF12780.2 EGC38443.1 - 0.063 12.2 0.1 0.15 10.9 0.0 1.6 1 1 1 2 2 2 0 P-loop containing dynein motor region D4 Cwf_Cwc_15 PF04889.7 EGC38444.1 - 1.2e-44 152.8 48.9 1.7e-43 149.1 33.9 1.9 1 1 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein Utp14 PF04615.8 EGC38444.1 - 0.13 10.4 39.2 0.14 10.3 27.2 1.1 1 0 0 1 1 1 0 Utp14 protein Herpes_DNAp_acc PF04929.7 EGC38444.1 - 4.4 6.1 12.8 2.4 7.0 6.5 2.0 1 1 0 2 2 2 0 Herpes DNA replication accessory factor DSPc PF00782.15 EGC38445.1 - 5.8e-38 129.4 0.0 1.2e-37 128.5 0.0 1.5 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EGC38445.1 - 8.7e-07 29.2 0.1 3.8e-05 23.9 0.0 2.7 2 1 0 2 2 2 1 Rhodanese-like domain Y_phosphatase PF00102.22 EGC38445.1 - 5.5e-05 22.6 0.0 0.0001 21.7 0.0 1.5 1 0 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGC38445.1 - 6.6e-05 22.9 0.0 0.00014 21.9 0.0 1.7 1 0 0 1 1 1 1 Inositol hexakisphosphate Y_phosphatase3 PF13350.1 EGC38445.1 - 0.024 14.9 0.2 0.69 10.1 0.0 2.9 3 1 0 3 3 3 0 Tyrosine phosphatase family DSPc PF00782.15 EGC38446.1 - 3.9e-36 123.5 0.2 9e-36 122.3 0.1 1.6 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Rhodanese PF00581.15 EGC38446.1 - 3.1e-09 37.1 0.4 1.7e-06 28.3 0.0 2.7 2 1 1 3 3 3 2 Rhodanese-like domain Y_phosphatase PF00102.22 EGC38446.1 - 0.00041 19.7 2.2 0.0016 17.8 0.0 2.3 2 1 0 2 2 2 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGC38446.1 - 0.015 15.3 0.0 0.034 14.1 0.0 1.5 1 1 0 1 1 1 0 Inositol hexakisphosphate HORMA PF02301.13 EGC38447.1 - 5.7e-44 150.0 0.2 6.6e-44 149.8 0.1 1.0 1 0 0 1 1 1 1 HORMA domain SspB PF04386.8 EGC38447.1 - 0.052 13.1 0.1 0.32 10.5 0.0 2.0 1 1 0 2 2 2 0 Stringent starvation protein B Hpr_kinase_N PF02603.11 EGC38447.1 - 0.065 12.9 0.0 0.13 11.9 0.0 1.6 1 0 0 1 1 1 0 HPr Serine kinase N terminus UbiA PF01040.13 EGC38448.1 - 1.6e-10 40.6 6.5 2e-10 40.3 4.5 1.2 1 0 0 1 1 1 1 UbiA prenyltransferase family F5_F8_type_C PF00754.20 EGC38449.1 - 5e-23 81.3 4.0 5e-23 81.3 2.8 1.9 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC38449.1 - 5.1e-21 74.1 0.1 1.2e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain Proteasome PF00227.21 EGC38450.1 - 6e-31 107.2 0.0 7.3e-31 106.9 0.0 1.1 1 0 0 1 1 1 1 Proteasome subunit Fz PF01392.17 EGC38451.1 - 8e-05 22.9 1.8 0.00011 22.5 1.2 1.3 1 0 0 1 1 1 1 Fz domain Folate_rec PF03024.9 EGC38451.1 - 0.013 15.1 3.4 0.065 12.8 2.3 1.8 1 1 0 1 1 1 0 Folate receptor family PA14 PF07691.7 EGC38453.1 - 9.8e-18 64.1 0.1 1.6e-17 63.4 0.1 1.3 1 0 0 1 1 1 1 PA14 domain Dicty_CTDC PF00526.13 EGC38453.1 - 0.00011 21.9 5.2 0.00011 21.9 3.6 13.8 14 2 1 15 15 15 3 Dictyostelium (slime mold) repeat p450 PF00067.17 EGC38455.1 - 2.5e-60 204.3 2.3 3.3e-60 203.9 1.6 1.2 1 0 0 1 1 1 1 Cytochrome P450 TFIID-31kDa PF02291.10 EGC38456.1 - 1.9e-46 157.0 0.1 2.1e-46 156.8 0.1 1.0 1 0 0 1 1 1 1 Transcription initiation factor IID, 31kD subunit CENP-S PF15630.1 EGC38456.1 - 3.7e-05 23.8 0.0 5e-05 23.4 0.0 1.2 1 0 0 1 1 1 1 Kinetochore component CENP-S Bromo_TP PF07524.8 EGC38456.1 - 7.8e-05 22.3 0.0 0.00011 21.8 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID_30kDa PF03540.8 EGC38456.1 - 0.0014 18.4 0.1 0.0028 17.4 0.0 1.5 1 0 0 1 1 1 1 Transcription initiation factor TFIID 23-30kDa subunit Histone PF00125.19 EGC38456.1 - 0.015 15.3 0.0 0.023 14.8 0.0 1.3 1 0 0 1 1 1 0 Core histone H2A/H2B/H3/H4 2-oxoacid_dh PF00198.18 EGC38457.1 - 4.2e-72 242.1 0.1 7.5e-72 241.3 0.0 1.4 1 1 1 2 2 2 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) E3_binding PF02817.12 EGC38457.1 - 2.1e-07 30.4 0.0 3.9e-07 29.6 0.0 1.5 1 0 0 1 1 1 1 e3 binding domain Tubulin PF00091.20 EGC38458.1 - 4.1e-74 249.0 0.0 1.1e-73 247.6 0.0 1.7 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGC38458.1 - 2.2e-49 166.6 0.5 2.2e-49 166.6 0.4 1.7 2 0 0 2 2 2 1 Tubulin C-terminal domain Misat_Tub_SegII PF10644.4 EGC38458.1 - 4e-07 30.0 0.0 1e-06 28.7 0.0 1.7 1 0 0 1 1 1 1 Misato Segment II tubulin-like domain GST_C PF00043.20 EGC38459.1 - 2.3e-10 40.2 0.0 3.5e-10 39.7 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_3 PF13417.1 EGC38459.1 - 4.7e-07 29.9 0.0 9.1e-07 29.0 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC38459.1 - 9.3e-07 28.9 0.0 2.6e-06 27.5 0.0 1.8 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC38459.1 - 1.4e-06 28.0 0.0 3.2e-06 26.9 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC38459.1 - 9.9e-06 25.9 0.0 1.6e-05 25.2 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC38459.1 - 0.00047 20.1 0.0 0.00079 19.3 0.0 1.4 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain Tmemb_14 PF03647.8 EGC38460.1 - 2.2e-20 72.8 7.8 2.9e-20 72.4 5.4 1.1 1 0 0 1 1 1 1 Transmembrane proteins 14C DUF1774 PF08611.5 EGC38460.1 - 0.0026 17.8 0.1 0.0047 17.0 0.0 1.4 2 0 0 2 2 2 1 Fungal protein of unknown function (DUF1774) ATP-synt_C PF00137.16 EGC38460.1 - 0.088 12.7 0.3 0.088 12.7 0.2 2.2 3 0 0 3 3 3 0 ATP synthase subunit C DUF2104 PF09877.4 EGC38460.1 - 0.15 12.0 2.9 0.33 10.9 0.7 2.1 1 1 1 2 2 2 0 Predicted membrane protein (DUF2104) DUF1049 PF06305.6 EGC38460.1 - 0.18 11.3 0.5 24 4.4 0.0 2.8 2 1 0 2 2 2 0 Protein of unknown function (DUF1049) UbiA PF01040.13 EGC38460.1 - 1.4 8.0 4.4 1.8 7.7 3.0 1.3 1 1 0 1 1 1 0 UbiA prenyltransferase family RVP PF00077.15 EGC38461.1 - 0.018 14.9 2.5 0.024 14.5 0.8 1.8 1 1 1 2 2 2 0 Retroviral aspartyl protease Oxysterol_BP PF01237.13 EGC38462.1 - 6.1e-43 146.6 4.2 8.6e-43 146.1 2.9 1.2 1 0 0 1 1 1 1 Oxysterol-binding protein NQR2_RnfD_RnfE PF03116.10 EGC38463.1 - 0.041 13.0 0.8 0.049 12.8 0.5 1.1 1 0 0 1 1 1 0 NQR2, RnfD, RnfE family RhoGEF PF00621.15 EGC38464.1 - 1.3e-53 181.5 3.5 1.3e-53 181.5 2.4 2.3 2 0 0 2 2 2 1 RhoGEF domain Methyltransf_7 PF03492.10 EGC38465.1 - 5.4e-17 61.5 3.2 7.1e-17 61.1 2.2 1.2 1 0 0 1 1 1 1 SAM dependent carboxyl methyltransferase Bin3 PF06859.7 EGC38465.1 - 0.00053 19.9 1.0 0.66 9.9 0.1 2.5 2 0 0 2 2 2 2 Bicoid-interacting protein 3 (Bin3) Methyltransf_11 PF08241.7 EGC38465.1 - 0.033 14.6 0.1 0.16 12.4 0.0 2.2 1 1 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38465.1 - 0.054 13.2 0.0 0.081 12.6 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain Repressor_Mnt PF11423.3 EGC38465.1 - 0.1 11.9 0.3 0.22 10.8 0.2 1.5 1 0 0 1 1 1 0 Regulatory protein Mnt COX6B PF02297.12 EGC38466.1 - 0.46 10.5 3.3 16 5.5 0.0 3.2 3 0 0 3 3 3 0 Cytochrome oxidase c subunit VIb B_lectin PF01453.19 EGC38467.1 - 1.9e-15 56.7 0.2 2.4e-12 46.7 0.0 2.1 1 1 1 2 2 2 2 D-mannose binding lectin DPPIV_N PF00930.16 EGC38467.1 - 0.0057 15.2 0.1 0.0065 15.1 0.1 1.1 1 0 0 1 1 1 1 Dipeptidyl peptidase IV (DPP IV) N-terminal region Coiled PF05710.7 EGC38468.1 - 8.9e-17 61.3 18.7 1e-16 61.1 12.9 1.0 1 0 0 1 1 1 1 Coiled coil Chlorosome_CsmC PF11098.3 EGC38468.1 - 0.75 9.5 4.0 1.3 8.6 2.8 1.4 1 0 0 1 1 1 0 Chlorosome envelope protein C DUF1517 PF07466.6 EGC38468.1 - 1.3 7.9 3.9 1.4 7.8 2.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Bacteriocin_IIc PF10439.4 EGC38468.1 - 1.5 8.9 12.6 2.2 8.4 8.7 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide Gly-zipper_YMGG PF13441.1 EGC38468.1 - 7.3 6.1 11.7 12 5.5 8.1 1.4 1 0 0 1 1 1 0 YMGG-like Gly-zipper Abhydrolase_5 PF12695.2 EGC38469.1 - 3.5e-20 72.2 0.0 7e-20 71.2 0.0 1.5 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC38469.1 - 6e-12 45.9 0.0 1.7e-11 44.4 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC38469.1 - 3.4e-09 36.5 8.4 1.4e-06 28.0 0.1 3.4 2 1 1 3 3 3 2 alpha/beta hydrolase fold Peptidase_S15 PF02129.13 EGC38469.1 - 1.2e-07 31.4 9.1 0.00029 20.3 0.0 3.3 2 1 0 3 3 3 2 X-Pro dipeptidyl-peptidase (S15 family) FSH1 PF03959.8 EGC38469.1 - 0.00019 20.9 1.7 0.00041 19.8 0.0 2.2 2 0 0 2 2 2 1 Serine hydrolase (FSH1) AXE1 PF05448.7 EGC38469.1 - 0.0021 16.6 0.0 0.019 13.5 0.0 2.1 1 1 1 2 2 2 1 Acetyl xylan esterase (AXE1) Trehalase_Ca-bi PF07492.6 EGC38469.1 - 0.0061 15.8 0.0 0.011 14.9 0.0 1.4 1 0 0 1 1 1 1 Neutral trehalase Ca2+ binding domain Hydrolase_4 PF12146.3 EGC38469.1 - 0.0069 16.2 0.0 0.013 15.3 0.0 1.5 1 0 0 1 1 1 1 Putative lysophospholipase PcfK PF14058.1 EGC38469.1 - 0.015 15.4 11.6 0.036 14.2 8.1 1.7 1 0 0 1 1 1 0 PcfK-like protein DUF2232 PF09991.4 EGC38469.1 - 2.9 6.8 4.1 5 6.0 2.8 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2232) LMBR1 PF04791.11 EGC38469.1 - 7.4 5.0 11.5 0.073 11.6 1.2 2.0 2 0 0 2 2 2 0 LMBR1-like membrane protein DUF4175 PF13779.1 EGC38469.1 - 8.4 3.9 22.8 15 3.0 15.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) G6PD_C PF02781.11 EGC38470.1 - 4.3e-125 416.4 0.0 7.5e-125 415.6 0.0 1.3 2 0 0 2 2 2 1 Glucose-6-phosphate dehydrogenase, C-terminal domain G6PD_N PF00479.17 EGC38470.1 - 3.3e-58 196.9 0.1 4.7e-58 196.4 0.1 1.2 1 0 0 1 1 1 1 Glucose-6-phosphate dehydrogenase, NAD binding domain Vpu PF00558.14 EGC38471.1 - 0.05 13.1 0.1 0.096 12.2 0.0 1.4 1 0 0 1 1 1 0 Vpu protein Ly49 PF08391.5 EGC38471.1 - 0.052 13.6 0.3 0.052 13.6 0.2 1.9 2 0 0 2 2 2 0 Ly49-like protein, N-terminal region DUF912 PF06024.7 EGC38471.1 - 0.056 13.5 0.4 0.099 12.7 0.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Arf PF00025.16 EGC38472.1 - 5.5e-37 126.6 0.0 6.3e-37 126.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family SRPRB PF09439.5 EGC38472.1 - 5.5e-11 41.9 0.0 8e-11 41.4 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Miro PF08477.8 EGC38472.1 - 3.4e-09 37.2 0.0 4.6e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein AAA_17 PF13207.1 EGC38472.1 - 2.8e-05 24.9 0.0 3.6e-05 24.5 0.0 1.2 1 0 0 1 1 1 1 AAA domain G-alpha PF00503.15 EGC38472.1 - 3.1e-05 22.8 0.2 0.0053 15.4 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit AAA_25 PF13481.1 EGC38472.1 - 0.00055 19.3 0.0 0.00068 19.0 0.0 1.1 1 0 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC38472.1 - 0.0011 18.8 0.2 0.002 18.0 0.1 1.6 1 1 0 1 1 1 1 AAA domain PduV-EutP PF10662.4 EGC38472.1 - 0.002 17.5 0.7 0.005 16.3 0.4 1.8 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation Ras PF00071.17 EGC38472.1 - 0.0023 17.3 0.3 0.019 14.3 0.2 2.0 1 1 0 1 1 1 1 Ras family ABC_tran PF00005.22 EGC38472.1 - 0.0051 17.1 0.0 0.0065 16.7 0.0 1.3 1 1 0 1 1 1 1 ABC transporter AAA_33 PF13671.1 EGC38472.1 - 0.0058 16.5 0.0 0.011 15.5 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC38472.1 - 0.016 14.3 0.0 0.024 13.7 0.0 1.3 1 0 0 1 1 1 0 Zeta toxin AAA_23 PF13476.1 EGC38472.1 - 0.03 14.6 0.4 0.079 13.2 0.0 1.6 1 1 1 2 2 2 0 AAA domain AAA_29 PF13555.1 EGC38472.1 - 0.03 13.8 0.0 0.056 12.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain MMR_HSR1 PF01926.18 EGC38472.1 - 0.035 14.0 0.2 0.079 12.9 0.1 1.7 1 1 0 1 1 1 0 50S ribosome-binding GTPase AAA_22 PF13401.1 EGC38472.1 - 0.036 14.2 0.0 0.052 13.6 0.0 1.5 1 1 0 1 1 1 0 AAA domain STAS PF01740.16 EGC38472.1 - 0.043 13.2 0.1 0.1 11.9 0.0 1.7 2 0 0 2 2 2 0 STAS domain AAA_24 PF13479.1 EGC38472.1 - 0.043 13.3 0.1 0.068 12.7 0.1 1.3 1 0 0 1 1 1 0 AAA domain cobW PF02492.14 EGC38472.1 - 0.045 13.2 1.8 0.7 9.3 0.2 2.1 1 1 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain SRP54 PF00448.17 EGC38472.1 - 0.054 12.9 0.1 0.087 12.2 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain Mg_chelatase PF01078.16 EGC38472.1 - 0.07 12.2 0.0 0.11 11.6 0.0 1.3 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI GTP_EFTU PF00009.22 EGC38472.1 - 0.074 12.4 0.1 4.7 6.5 0.0 2.1 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGC38472.1 - 0.075 13.0 0.0 0.087 12.8 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain AAA_28 PF13521.1 EGC38472.1 - 0.078 12.9 0.1 0.13 12.2 0.1 1.4 1 0 0 1 1 1 0 AAA domain NmrA PF05368.8 EGC38472.1 - 0.082 12.1 0.1 0.62 9.2 0.0 1.9 2 0 0 2 2 2 0 NmrA-like family AAA_5 PF07728.9 EGC38472.1 - 0.086 12.5 0.1 0.18 11.5 0.1 1.6 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGC38472.1 - 0.11 12.7 0.2 0.21 11.8 0.1 1.7 1 1 0 1 1 1 0 AAA domain DUF655 PF04919.7 EGC38473.1 - 0.00058 19.6 0.0 0.0029 17.3 0.0 2.2 1 0 0 1 1 1 1 Protein of unknown function (DUF655) zf-rbx1 PF12678.2 EGC38473.1 - 0.0035 17.4 4.5 0.0035 17.4 3.1 2.4 2 0 0 2 2 2 1 RING-H2 zinc finger Endonuclease_5 PF04493.9 EGC38474.1 - 2e-61 206.9 0.0 4.1e-61 205.9 0.0 1.4 1 1 0 1 1 1 1 Endonuclease V AMP-binding PF00501.23 EGC38475.1 - 2.5e-76 256.7 0.0 3e-76 256.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding PF00501.23 EGC38476.1 - 1.1e-75 254.5 0.0 1.4e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme Oxidored_nitro PF00148.14 EGC38476.1 - 0.072 11.7 0.0 0.13 10.8 0.0 1.3 1 0 0 1 1 1 0 Nitrogenase component 1 type Oxidoreductase AMP-binding PF00501.23 EGC38477.1 - 3.2e-81 272.8 0.0 4.2e-81 272.4 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme ABC2_membrane PF01061.19 EGC38478.1 - 3e-35 121.2 17.6 5e-35 120.5 12.2 1.3 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC38478.1 - 1.7e-25 89.9 0.0 3.7e-25 88.8 0.0 1.6 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC38478.1 - 1e-08 35.5 0.2 1.2e-07 32.0 0.1 2.4 1 1 0 1 1 1 1 AAA domain ABC2_membrane_3 PF12698.2 EGC38478.1 - 9.4e-08 31.4 8.2 9.4e-08 31.4 5.7 1.8 2 0 0 2 2 2 1 ABC-2 family transporter protein AAA_25 PF13481.1 EGC38478.1 - 4.8e-05 22.8 0.0 0.0019 17.6 0.0 2.3 2 0 0 2 2 2 1 AAA domain DUF258 PF03193.11 EGC38478.1 - 0.00013 21.1 0.0 0.00026 20.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_19 PF13245.1 EGC38478.1 - 0.00082 19.0 0.0 0.0015 18.2 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain SMC_N PF02463.14 EGC38478.1 - 0.0018 17.5 0.2 1.6 7.9 0.1 3.0 3 0 0 3 3 3 1 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC38478.1 - 0.0073 15.8 0.6 0.015 14.8 0.4 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain T2SE PF00437.15 EGC38478.1 - 0.012 14.5 0.1 0.022 13.6 0.1 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_10 PF12846.2 EGC38478.1 - 0.015 14.7 0.6 0.031 13.7 0.4 1.5 1 0 0 1 1 1 0 AAA-like domain AAA_15 PF13175.1 EGC38478.1 - 0.015 14.3 14.3 0.044 12.8 0.2 3.1 3 0 0 3 3 3 0 AAA ATPase domain AAA_16 PF13191.1 EGC38478.1 - 0.027 14.4 0.0 0.043 13.7 0.0 1.4 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EGC38478.1 - 0.039 13.5 0.1 0.063 12.8 0.1 1.3 1 0 0 1 1 1 0 AAA domain NACHT PF05729.7 EGC38478.1 - 0.047 13.3 0.0 0.086 12.4 0.0 1.5 1 0 0 1 1 1 0 NACHT domain cobW PF02492.14 EGC38478.1 - 0.057 12.8 0.2 0.1 12.0 0.1 1.4 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGC38478.1 - 0.06 12.8 0.1 0.1 12.0 0.1 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family NTPase_1 PF03266.10 EGC38478.1 - 0.07 12.8 2.4 0.13 11.9 0.3 2.1 2 0 0 2 2 2 0 NTPase ABC_ATPase PF09818.4 EGC38478.1 - 0.084 11.4 0.2 0.14 10.7 0.2 1.2 1 0 0 1 1 1 0 Predicted ATPase of the ABC class MMR_HSR1 PF01926.18 EGC38478.1 - 0.095 12.6 0.1 0.25 11.2 0.1 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase AAA_28 PF13521.1 EGC38478.1 - 0.11 12.3 0.8 0.21 11.5 0.6 1.4 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGC38478.1 - 2.2 8.5 9.4 11 6.2 6.5 2.2 1 1 0 1 1 1 0 AAA domain Eapp_C PF10238.4 EGC38480.1 - 0.0089 15.9 6.1 0.0099 15.7 4.2 1.2 1 0 0 1 1 1 1 E2F-associated phosphoprotein DUF912 PF06024.7 EGC38480.1 - 0.022 14.8 5.7 0.025 14.6 4.0 1.2 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2956 PF11169.3 EGC38480.1 - 0.14 12.1 0.9 0.2 11.6 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) ImmE5 PF11480.3 EGC38480.1 - 0.21 11.4 3.2 0.29 10.9 2.2 1.3 1 0 0 1 1 1 0 Colicin-E5 Imm protein Apc15p PF05841.6 EGC38480.1 - 0.35 11.6 8.4 0.45 11.2 5.8 1.2 1 0 0 1 1 1 0 Apc15p protein V-set PF07686.12 EGC38480.1 - 0.54 10.1 4.9 0.74 9.7 3.4 1.2 1 0 0 1 1 1 0 Immunoglobulin V-set domain DUF3300 PF11737.3 EGC38480.1 - 9.5 5.4 8.5 11 5.1 5.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3300) ORC4_C PF14629.1 EGC38481.1 - 4.8e-22 78.3 0.1 7.6e-22 77.7 0.1 1.3 1 0 0 1 1 1 1 Origin recognition complex (ORC) subunit 4 C-terminus Arch_ATPase PF01637.13 EGC38481.1 - 2.3e-07 30.7 2.7 2.3e-07 30.7 1.9 1.9 2 0 0 2 2 2 1 Archaeal ATPase AAA PF00004.24 EGC38481.1 - 1.9e-06 28.1 0.8 4.5e-06 26.8 0.1 2.0 2 1 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC38481.1 - 4.8e-06 26.7 0.0 1.4e-05 25.2 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC38481.1 - 6.6e-06 26.2 0.0 1.6e-05 24.9 0.0 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_14 PF13173.1 EGC38481.1 - 0.0001 22.2 0.1 0.0001 22.2 0.1 2.6 3 1 0 3 3 3 1 AAA domain DUF815 PF05673.8 EGC38481.1 - 0.00049 19.0 0.0 0.00088 18.2 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_35 PF14516.1 EGC38481.1 - 0.0036 15.9 0.4 0.0068 15.0 0.1 1.6 2 0 0 2 2 2 1 AAA-like domain NACHT PF05729.7 EGC38481.1 - 0.02 14.5 0.0 1.3 8.6 0.0 2.7 2 1 0 2 2 2 0 NACHT domain Cdc6_C PF09079.6 EGC38481.1 - 0.029 14.0 0.2 0.23 11.2 0.0 2.4 3 0 0 3 3 3 0 CDC6, C terminal T2SE PF00437.15 EGC38481.1 - 0.051 12.4 0.0 0.089 11.6 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein PEP-utilizers PF00391.18 EGC38481.1 - 0.082 12.4 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 PEP-utilising enzyme, mobile domain Rpr2 PF04032.11 EGC38482.1 - 0.02 14.7 3.5 0.066 13.0 2.3 2.0 1 1 0 1 1 1 0 RNAse P Rpr2/Rpp21/SNM1 subunit domain Amino_oxidase PF01593.19 EGC38483.1 - 1.2e-46 159.7 0.0 1.9e-46 159.1 0.0 1.3 1 1 0 1 1 1 1 Flavin containing amine oxidoreductase NAD_binding_8 PF13450.1 EGC38483.1 - 2.5e-11 43.4 0.1 4.9e-11 42.4 0.1 1.5 1 0 0 1 1 1 1 NAD(P)-binding Rossmann-like domain GIDA PF01134.17 EGC38483.1 - 2.8e-05 23.1 0.5 0.0036 16.2 0.0 2.4 3 0 0 3 3 3 2 Glucose inhibited division protein A FAD_binding_2 PF00890.19 EGC38483.1 - 0.00024 20.1 0.0 0.00032 19.6 0.0 1.1 1 0 0 1 1 1 1 FAD binding domain Pyr_redox_3 PF13738.1 EGC38483.1 - 0.00059 19.9 0.1 0.0016 18.5 0.0 1.7 2 0 0 2 2 2 1 Pyridine nucleotide-disulphide oxidoreductase DAO PF01266.19 EGC38483.1 - 0.0016 17.3 0.0 0.0057 15.6 0.0 1.8 2 0 0 2 2 2 1 FAD dependent oxidoreductase HI0933_like PF03486.9 EGC38483.1 - 0.0036 15.8 0.0 0.014 13.9 0.0 1.8 2 0 0 2 2 2 1 HI0933-like protein Thi4 PF01946.12 EGC38483.1 - 0.0059 15.7 0.1 0.02 13.9 0.0 1.9 2 0 0 2 2 2 1 Thi4 family Pyr_redox PF00070.22 EGC38483.1 - 0.03 14.7 0.1 0.17 12.3 0.0 2.1 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox_2 PF07992.9 EGC38483.1 - 0.033 14.0 0.0 0.5 10.2 0.0 2.4 3 0 0 3 3 3 0 Pyridine nucleotide-disulphide oxidoreductase Lycopene_cycl PF05834.7 EGC38483.1 - 0.043 12.7 0.0 1.4 7.8 0.0 2.1 2 0 0 2 2 2 0 Lycopene cyclase protein FAD_oxidored PF12831.2 EGC38483.1 - 0.16 10.9 0.0 0.24 10.4 0.0 1.3 1 0 0 1 1 1 0 FAD dependent oxidoreductase FAD_binding_3 PF01494.14 EGC38483.1 - 0.21 10.6 0.0 0.3 10.0 0.0 1.2 1 0 0 1 1 1 0 FAD binding domain FUSC_2 PF13515.1 EGC38484.1 - 1.8e-14 53.7 34.0 3.1e-12 46.5 9.7 2.4 2 0 0 2 2 2 2 Fusaric acid resistance protein-like Vpu PF00558.14 EGC38484.1 - 0.17 11.4 4.9 0.061 12.8 0.3 2.6 2 0 0 2 2 2 0 Vpu protein adh_short_C2 PF13561.1 EGC38485.1 - 0.0022 17.7 0.0 0.0045 16.7 0.0 1.4 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGC38485.1 - 0.0029 17.5 0.0 0.0044 16.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Nucleoporin_FG PF13634.1 EGC38486.1 - 1.5e-36 125.0 282.1 3.7e-10 40.0 26.6 7.9 1 1 7 8 8 8 8 Nucleoporin FG repeat region Nsp1_C PF05064.8 EGC38486.1 - 7.5e-25 86.8 9.7 7.5e-25 86.8 6.7 2.6 1 1 1 2 2 2 1 Nsp1-like C-terminal region Cauli_AT PF03233.8 EGC38486.1 - 2.1 8.0 12.9 1.2 8.7 5.0 2.4 2 0 0 2 2 2 0 Aphid transmission protein Syntaxin PF00804.20 EGC38486.1 - 2.3 8.4 16.6 4.1 7.6 3.2 2.4 1 1 1 2 2 2 0 Syntaxin DUF45 PF01863.12 EGC38486.1 - 2.7 7.7 6.8 1 9.1 3.1 1.4 2 0 0 2 2 2 0 Protein of unknown function DUF45 Tropomyosin_1 PF12718.2 EGC38486.1 - 6.7 6.5 13.7 5.6 6.8 7.9 1.8 1 1 1 2 2 2 0 Tropomyosin like DIOX_N PF14226.1 EGC38487.1 - 4.8e-25 88.3 0.2 1.4e-24 86.8 0.0 1.8 2 0 0 2 2 2 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC38487.1 - 1.2e-19 70.4 0.0 2.3e-19 69.5 0.0 1.5 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF3377 PF11857.3 EGC38488.1 - 0.012 15.2 0.1 0.025 14.1 0.1 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3377) SKG6 PF08693.5 EGC38488.1 - 0.058 12.7 4.2 0.18 11.1 2.9 1.9 1 0 0 1 1 1 0 Transmembrane alpha-helix domain DUF3816 PF12822.2 EGC38488.1 - 1.1 9.1 9.9 0.056 13.3 1.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF3816) DnaJ PF00226.26 EGC38489.1 - 0.00027 20.6 0.1 0.00027 20.6 0.1 2.6 3 0 0 3 3 3 1 DnaJ domain WEMBL PF05701.6 EGC38489.1 - 0.0093 14.4 31.4 0.077 11.4 10.9 2.4 1 1 0 2 2 2 2 Weak chloroplast movement under blue light Hormone_3 PF00159.13 EGC38489.1 - 0.18 11.8 2.0 4.1 7.4 0.1 2.7 2 0 0 2 2 2 0 Pancreatic hormone peptide DUF948 PF06103.6 EGC38489.1 - 0.28 11.0 11.7 0.43 10.4 2.6 3.2 2 1 0 2 2 2 0 Bacterial protein of unknown function (DUF948) RNaseH_C PF09293.5 EGC38490.1 - 0.003 17.4 0.1 0.0047 16.8 0.1 1.3 1 1 0 1 1 1 1 T4 RNase H, C terminal Cas_Csx8 PF09657.5 EGC38492.1 - 0.088 11.5 1.0 0.089 11.5 0.7 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) Cas_Csx8 PF09657.5 EGC38493.1 - 0.11 11.2 0.2 0.12 11.0 0.1 1.0 1 0 0 1 1 1 0 CRISPR-associated protein Csx8 (Cas_Csx8) Mpv17_PMP22 PF04117.7 EGC38494.1 - 8.2e-25 86.2 1.6 1.8e-24 85.1 0.6 1.9 2 0 0 2 2 2 1 Mpv17 / PMP22 family UQ_con PF00179.21 EGC38495.1 - 1.3e-23 83.0 0.3 3.9e-23 81.4 0.0 2.1 2 0 0 2 2 2 1 Ubiquitin-conjugating enzyme UEV PF05743.8 EGC38495.1 - 0.0011 18.6 0.2 0.0044 16.6 0.0 2.0 2 0 0 2 2 2 1 UEV domain ketoacyl-synt PF00109.21 EGC38496.1 - 3.3e-36 125.0 0.0 5.8e-36 124.2 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38496.1 - 2.6e-35 122.2 0.0 2.6e-26 92.7 0.0 2.4 1 1 1 2 2 2 2 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38496.1 - 1.3e-31 108.8 0.0 2.5e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38496.1 - 1.2e-26 93.5 0.0 5.5e-26 91.3 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC38496.1 - 1.5e-19 70.2 0.0 1.5e-19 70.2 0.0 3.0 3 0 0 3 3 1 1 Methyltransferase domain PS-DH PF14765.1 EGC38496.1 - 3e-18 66.0 0.0 4.4e-18 65.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC38496.1 - 3.2e-18 66.1 0.0 1.3e-17 64.1 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EGC38496.1 - 4.2e-11 42.5 0.0 9.2e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38496.1 - 2.9e-09 37.8 0.0 8.5e-09 36.3 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38496.1 - 3.5e-09 36.3 0.0 8.4e-09 35.1 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38496.1 - 1.4e-08 35.1 0.0 9.4e-08 32.4 0.0 2.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38496.1 - 1.7e-08 34.3 0.0 6.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38496.1 - 8.5e-05 23.1 0.0 0.0037 17.8 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 EGC38496.1 - 0.00012 22.3 0.1 0.00031 20.9 0.0 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC38496.1 - 0.087 11.7 0.0 0.17 10.8 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC38497.1 - 2.7e-59 200.7 0.0 4.1e-59 200.1 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38497.1 - 5.3e-46 157.4 0.0 8.5e-46 156.7 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38497.1 - 1.3e-31 108.9 0.0 2.4e-31 108.0 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38497.1 - 1.2e-26 93.4 0.0 6.1e-26 91.1 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC38497.1 - 6.5e-20 71.4 0.0 6.5e-20 71.4 0.0 3.4 4 0 0 4 4 2 1 Methyltransferase domain adh_short PF00106.20 EGC38497.1 - 1.7e-18 67.0 0.0 6.8e-18 65.1 0.0 1.9 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGC38497.1 - 2.6e-18 66.2 0.0 3.9e-18 65.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N PF00107.21 EGC38497.1 - 3.8e-11 42.6 0.0 8.8e-11 41.4 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38497.1 - 8.9e-10 39.5 0.0 2.3e-09 38.2 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC38497.1 - 2.9e-09 36.8 0.0 1.4e-08 34.6 0.0 2.2 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EGC38497.1 - 3.1e-09 36.5 0.0 8.2e-09 35.2 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38497.1 - 3.4e-09 37.0 0.0 2.6e-08 34.2 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38497.1 - 3.1e-06 27.7 0.0 0.00012 22.6 0.0 3.3 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 EGC38497.1 - 0.00036 20.7 0.1 0.00096 19.3 0.1 1.7 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC38497.1 - 0.05 12.5 0.1 0.1 11.5 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain ketoacyl-synt PF00109.21 EGC38498.1 - 4.2e-59 200.0 0.0 6e-59 199.5 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38498.1 - 1.1e-44 153.0 0.0 1.8e-44 152.3 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38498.1 - 1.4e-31 108.8 0.0 2.6e-31 107.9 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38498.1 - 1.9e-25 89.5 0.0 9.2e-25 87.3 0.0 1.9 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC38498.1 - 2.5e-20 72.7 0.0 2.5e-20 72.7 0.0 2.9 3 0 0 3 3 1 1 Methyltransferase domain PS-DH PF14765.1 EGC38498.1 - 1.1e-18 67.4 0.0 1.6e-18 66.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC38498.1 - 4.6e-15 55.9 0.0 1.3e-14 54.4 0.0 1.8 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N PF00107.21 EGC38498.1 - 5.8e-11 42.0 0.0 1.2e-10 41.0 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38498.1 - 1.4e-09 37.6 0.0 3.6e-09 36.3 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC38498.1 - 3.5e-09 36.6 0.0 1.2e-08 34.8 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38498.1 - 8e-09 35.8 0.0 3.8e-08 33.6 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC38498.1 - 1.2e-08 35.8 0.0 3.1e-08 34.5 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_18 PF12847.2 EGC38498.1 - 3.3e-06 27.6 0.0 0.00011 22.8 0.0 3.0 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 EGC38498.1 - 0.00017 21.7 0.2 0.00049 20.3 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site OB_NTP_bind PF07717.11 EGC38499.1 - 2.4e-14 53.1 0.1 4.5e-14 52.2 0.1 1.5 1 0 0 1 1 1 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGC38499.1 - 3.9e-12 46.0 0.1 1.8e-11 43.9 0.1 2.0 1 1 0 1 1 1 1 Helicase associated domain (HA2) CMAS PF02353.15 EGC38501.1 - 1.8e-70 237.1 2.6 2e-70 236.9 1.4 1.4 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase Methyltransf_23 PF13489.1 EGC38501.1 - 4.3e-11 42.8 0.0 7.3e-11 42.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38501.1 - 3.5e-09 37.0 0.0 1.9e-08 34.6 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38501.1 - 1e-08 35.7 0.0 2e-08 34.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC38501.1 - 1.6e-08 34.9 0.0 3e-08 34.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38501.1 - 4.8e-08 32.7 0.1 1.2e-07 31.4 0.1 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC38501.1 - 3.6e-05 24.0 0.0 8.4e-05 22.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC38501.1 - 0.00014 21.8 0.0 0.00024 21.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_4 PF02390.12 EGC38501.1 - 0.00031 19.8 0.0 0.00067 18.7 0.0 1.5 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGC38501.1 - 0.0034 16.7 0.0 0.0063 15.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain ADH_zinc_N PF00107.21 EGC38501.1 - 0.0037 16.8 0.0 0.0067 15.9 0.0 1.4 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PCMT PF01135.14 EGC38501.1 - 0.014 14.9 0.0 0.024 14.1 0.0 1.3 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_PK PF05891.7 EGC38501.1 - 0.015 14.6 0.0 0.025 13.8 0.0 1.3 1 0 0 1 1 1 0 AdoMet dependent proline di-methyltransferase MetW PF07021.7 EGC38501.1 - 0.038 13.3 0.0 0.068 12.5 0.0 1.4 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW Methyltransf_20 PF12147.3 EGC38501.1 - 0.11 11.3 0.0 0.2 10.4 0.0 1.4 1 0 0 1 1 1 0 Putative methyltransferase MscS_TM PF12794.2 EGC38502.1 - 0.003 16.2 0.2 0.0042 15.7 0.2 1.1 1 0 0 1 1 1 1 Mechanosensitive ion channel inner membrane domain 1 7TMR-DISM_7TM PF07695.6 EGC38502.1 - 0.0048 16.5 5.9 0.0067 16.1 4.1 1.1 1 0 0 1 1 1 1 7TM diverse intracellular signalling Claudin_2 PF13903.1 EGC38502.1 - 0.007 16.0 0.0 0.0099 15.5 0.0 1.1 1 0 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction Oxidored_q1_N PF00662.15 EGC38502.1 - 0.028 13.9 1.4 0.057 12.9 0.5 1.9 1 1 0 1 1 1 0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus FA_desaturase PF00487.19 EGC38502.1 - 0.49 9.8 3.8 0.13 11.6 0.5 1.5 2 0 0 2 2 2 0 Fatty acid desaturase DUF1279 PF06916.8 EGC38504.1 - 2.5e-22 78.9 0.5 5.9e-22 77.7 0.4 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1279) RNA_pol_Rpc4 PF05132.9 EGC38504.1 - 8.1e-05 22.6 1.5 0.00012 22.0 1.1 1.2 1 0 0 1 1 1 1 RNA polymerase III RPC4 Spore_coat_CotO PF14153.1 EGC38504.1 - 0.0021 17.5 11.2 0.0028 17.1 7.8 1.1 1 0 0 1 1 1 1 Spore coat protein CotO Tim54 PF11711.3 EGC38504.1 - 0.0064 15.1 0.2 0.008 14.8 0.1 1.1 1 0 0 1 1 1 1 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EGC38504.1 - 0.011 15.5 9.5 0.015 15.1 6.6 1.2 1 0 0 1 1 1 0 DDHD domain Tetraspannin PF00335.15 EGC38504.1 - 0.029 13.6 0.2 0.042 13.1 0.1 1.3 1 0 0 1 1 1 0 Tetraspanin family PPP4R2 PF09184.6 EGC38504.1 - 0.03 13.8 13.1 0.039 13.5 9.1 1.1 1 0 0 1 1 1 0 PPP4R2 DUF3595 PF12166.3 EGC38504.1 - 0.043 12.6 4.9 0.055 12.2 3.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3595) RP-C_C PF11800.3 EGC38504.1 - 0.051 13.2 5.9 0.075 12.7 4.1 1.2 1 0 0 1 1 1 0 Replication protein C C-terminal region SprA-related PF12118.3 EGC38504.1 - 0.35 10.1 12.4 0.44 9.8 8.6 1.0 1 0 0 1 1 1 0 SprA-related family Presenilin PF01080.12 EGC38504.1 - 0.83 8.4 5.3 1 8.0 3.7 1.1 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.7 EGC38504.1 - 3 7.7 10.9 3.8 7.3 7.5 1.1 1 0 0 1 1 1 0 GAGA binding protein-like family Sec7 PF01369.15 EGC38505.1 - 5.7e-37 127.2 3.1 1.6e-36 125.7 2.1 1.8 1 0 0 1 1 1 1 Sec7 domain Sec7_N PF12783.2 EGC38505.1 - 9.2e-29 100.0 12.5 9.2e-29 100.0 8.6 3.7 3 1 0 3 3 3 1 Guanine nucleotide exchange factor in Golgi transport N-terminal Ras PF00071.17 EGC38506.1 - 1.8e-55 186.7 1.9 2.1e-55 186.5 1.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38506.1 - 9.9e-23 80.8 0.2 1.4e-22 80.3 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38506.1 - 4.4e-13 48.8 0.2 5.5e-13 48.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC38506.1 - 4.4e-07 29.5 0.5 1.8e-06 27.5 0.4 1.8 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC38506.1 - 1.8e-05 24.0 0.3 2.1e-05 23.8 0.2 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC38506.1 - 6.3e-05 22.9 0.2 9.1e-05 22.3 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC38506.1 - 0.00011 21.4 0.0 0.00015 21.0 0.0 1.2 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGC38506.1 - 0.013 14.7 0.1 0.18 11.0 0.0 2.3 1 1 0 1 1 1 0 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC38506.1 - 0.026 13.9 0.0 0.1 12.1 0.0 1.9 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGC38506.1 - 0.034 14.1 0.0 0.056 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain G-alpha PF00503.15 EGC38506.1 - 0.065 11.9 0.4 5.8 5.4 0.1 2.4 1 1 1 2 2 2 0 G-protein alpha subunit BBS2_N PF14781.1 EGC38506.1 - 0.078 12.6 0.1 0.33 10.5 0.0 2.0 2 0 0 2 2 2 0 Ciliary BBSome complex subunit 2, N-terminal AAA_22 PF13401.1 EGC38506.1 - 0.12 12.5 0.0 0.21 11.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain Myb_DNA-binding PF00249.26 EGC38507.1 - 3.7e-15 55.6 4.7 2.8e-05 24.0 0.0 4.0 3 1 0 3 3 3 3 Myb-like DNA-binding domain TyeA PF09059.5 EGC38507.1 - 2.4 8.1 10.9 3.6 7.5 1.1 3.8 4 0 0 4 4 4 0 TyeA EGF_2 PF07974.8 EGC38508.1 - 0.008 16.3 8.7 0.019 15.1 6.0 1.6 1 0 0 1 1 1 1 EGF-like domain Methyltransf_12 PF08242.7 EGC38509.1 - 4.1 7.9 7.9 0.81 10.2 2.0 2.5 2 0 0 2 2 2 0 Methyltransferase domain FNIP PF05725.7 EGC38510.1 - 1.6e-106 348.0 65.9 5.2e-16 58.3 1.1 10.4 9 1 3 12 12 12 11 FNIP Repeat DUF1769 PF08588.5 EGC38510.1 - 1.2e-13 50.7 12.7 0.65 9.9 0.1 11.1 8 4 4 12 12 12 7 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC38510.1 - 1.7e-05 24.4 0.8 0.09 12.4 0.0 3.7 2 1 2 4 4 4 2 Leucine rich repeats (6 copies) Ank PF00023.25 EGC38511.1 - 6.3e-38 126.7 0.4 1.1e-06 28.1 0.0 6.8 7 0 0 7 7 7 6 Ankyrin repeat Ank_2 PF12796.2 EGC38511.1 - 2.2e-37 127.2 6.2 5.6e-17 61.8 0.1 3.7 2 2 1 3 3 3 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC38511.1 - 3.1e-34 113.5 1.2 4.8e-06 26.3 0.0 7.3 7 0 0 7 7 7 6 Ankyrin repeat Ank_5 PF13857.1 EGC38511.1 - 2.3e-31 107.0 1.1 2.5e-10 40.2 0.1 5.9 4 1 2 6 6 6 5 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC38511.1 - 1.7e-29 101.6 4.8 1.8e-10 41.0 0.0 6.1 3 2 4 7 7 7 6 Ankyrin repeats (many copies) UPF1_Zn_bind PF09416.5 EGC38511.1 - 0.1 12.1 1.6 0.21 11.1 1.1 1.5 1 0 0 1 1 1 0 RNA helicase (UPF2 interacting domain) Cellulase PF00150.13 EGC38513.1 - 3.3e-05 23.2 0.6 0.00011 21.5 0.4 1.7 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ketoacyl-synt PF00109.21 EGC38514.1 - 1.9e-64 217.6 0.0 2.7e-64 217.0 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38514.1 - 2.2e-44 152.1 0.0 3.6e-44 151.4 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38514.1 - 6.2e-31 106.7 0.0 1.3e-30 105.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38514.1 - 3.6e-27 95.1 0.0 1.8e-26 92.9 0.0 2.0 2 0 0 2 2 2 1 KR domain Methyltransf_12 PF08242.7 EGC38514.1 - 1.1e-20 73.8 0.0 1.1e-20 73.8 0.0 3.8 4 0 0 4 4 4 1 Methyltransferase domain adh_short PF00106.20 EGC38514.1 - 1.5e-18 67.2 0.0 6.2e-18 65.2 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase PS-DH PF14765.1 EGC38514.1 - 2.9e-18 66.0 0.0 4.2e-18 65.5 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EGC38514.1 - 1.5e-11 44.2 0.0 5.3e-11 42.5 0.0 1.9 2 0 0 2 2 2 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC38514.1 - 4.7e-09 37.2 0.0 1.2e-08 35.9 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38514.1 - 5.9e-09 35.6 0.0 1.7e-08 34.1 0.0 1.8 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38514.1 - 8.4e-08 32.6 0.0 4.1e-07 30.4 0.0 2.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38514.1 - 1.4e-05 24.7 0.1 1.4e-05 24.7 0.1 4.2 3 1 1 4 4 4 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38514.1 - 2.9e-05 24.5 0.0 0.0016 19.0 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC38514.1 - 0.0035 17.5 0.0 0.012 15.8 0.0 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC38514.1 - 0.065 12.1 0.0 0.13 11.1 0.0 1.4 1 0 0 1 1 1 0 Thiolase, N-terminal domain Cys_Met_Meta_PP PF01053.15 EGC38515.1 - 0.0014 17.0 0.0 0.0026 16.1 0.0 1.4 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGC38515.1 - 0.019 13.9 0.2 0.032 13.1 0.1 1.4 1 0 0 1 1 1 0 Aminotransferase class I and II Prokineticin PF06607.6 EGC38516.1 - 0.0026 17.8 6.1 0.01 15.9 4.2 1.8 1 1 0 1 1 1 1 Prokineticin EB PF01683.13 EGC38516.1 - 4.1 7.5 16.6 2.3 8.3 5.1 2.4 1 1 1 2 2 2 0 EB module Nucleoside_tran PF01733.13 EGC38517.1 - 0.38 9.8 3.0 0.48 9.5 2.1 1.2 1 0 0 1 1 1 0 Nucleoside transporter Secretin_N_2 PF07655.8 EGC38517.1 - 0.52 10.7 7.4 0.9 9.9 5.1 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain LacI PF00356.16 EGC38517.1 - 0.62 9.7 0.0 0.62 9.7 0.0 3.1 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family RhoGEF PF00621.15 EGC38518.1 - 3.6e-40 137.7 9.6 3.6e-40 137.7 6.6 6.5 3 3 3 6 6 6 1 RhoGEF domain IQ PF00612.22 EGC38518.1 - 0.0013 18.1 0.1 0.0035 16.8 0.1 1.8 1 0 0 1 1 1 1 IQ calmodulin-binding motif Med15 PF09606.5 EGC38518.1 - 4.1 5.4 101.4 0.74 7.9 36.2 2.5 2 0 0 2 2 2 0 ARC105 or Med15 subunit of Mediator complex non-fungal Med20 PF08612.6 EGC38520.1 - 2.4e-27 95.5 0.0 2.8e-27 95.3 0.0 1.1 1 0 0 1 1 1 1 TATA-binding related factor (TRF) of subunit 20 of Mediator complex DUF218 PF02698.12 EGC38521.1 - 3e-31 108.0 0.0 4.9e-31 107.3 0.0 1.3 1 0 0 1 1 1 1 DUF218 domain Methyltransf_18 PF12847.2 EGC38521.1 - 0.00059 20.3 0.0 0.033 14.7 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain Mem_trans PF03547.13 EGC38521.1 - 0.023 12.9 0.7 0.021 13.1 0.5 1.2 1 0 0 1 1 1 0 Membrane transport protein RED_N PF07808.8 EGC38521.1 - 0.49 9.5 18.2 0.59 9.2 7.9 2.4 2 0 0 2 2 2 0 RED-like protein N-terminal region DUF2570 PF10828.3 EGC38521.1 - 0.54 9.8 18.1 0.12 12.0 9.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF2570) VWA_3 PF13768.1 EGC38522.1 - 2.5e-27 95.4 0.0 1.8e-26 92.7 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT PF08487.5 EGC38522.1 - 1.1e-14 54.1 0.1 2.5e-14 52.9 0.0 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EGC38522.1 - 2.5e-09 37.1 0.0 7.6e-09 35.5 0.0 1.8 2 0 0 2 2 2 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC38522.1 - 5.7e-09 36.3 0.0 2.7e-08 34.1 0.0 2.1 2 0 0 2 2 2 1 von Willebrand factor type A domain VIT_2 PF13757.1 EGC38522.1 - 1.5e-05 24.3 0.0 3.1e-05 23.3 0.0 1.5 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain vWA-TerF-like PF10138.4 EGC38522.1 - 0.0016 18.2 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 vWA found in TerF C terminus DUF605 PF04652.11 EGC38522.1 - 0.47 9.8 11.0 0.76 9.1 7.6 1.3 1 0 0 1 1 1 0 Vta1 like DrsE PF02635.10 EGC38523.1 - 3.3e-15 56.2 0.0 3.8e-15 56.0 0.0 1.0 1 0 0 1 1 1 1 DsrE/DsrF-like family Homeobox PF00046.24 EGC38524.1 - 7.3e-18 63.9 4.0 1.6e-17 62.8 2.7 1.6 1 0 0 1 1 1 1 Homeobox domain Ank_2 PF12796.2 EGC38524.1 - 3.7e-07 30.3 0.5 2.8e-06 27.5 0.0 2.5 1 1 1 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC38524.1 - 4.4e-07 29.3 0.0 2.1e-06 27.2 0.0 2.2 2 0 0 2 2 2 1 Ankyrin repeat Ank_5 PF13857.1 EGC38524.1 - 9.8e-06 25.6 0.0 9.8e-06 25.6 0.0 3.3 3 1 0 3 3 3 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC38524.1 - 0.00024 21.0 0.0 0.0022 18.0 0.0 2.5 2 0 0 2 2 2 1 Ankyrin repeat Ank_4 PF13637.1 EGC38524.1 - 0.0011 19.4 0.0 0.0039 17.6 0.0 2.0 1 0 0 1 1 1 1 Ankyrin repeats (many copies) TetR_C_4 PF08359.6 EGC38525.1 - 0.087 12.7 2.7 0.17 11.7 0.1 2.5 2 1 1 3 3 3 0 YsiA-like protein, C-terminal region Zip PF02535.17 EGC38525.1 - 0.65 8.9 2.0 0.67 8.9 0.9 1.4 1 1 0 1 1 1 0 ZIP Zinc transporter NPR2 PF06218.6 EGC38526.1 - 1.9e-135 451.8 8.8 1.5e-132 442.3 6.1 2.0 1 1 0 1 1 1 1 Nitrogen permease regulator 2 NPR3 PF03666.8 EGC38526.1 - 1e-10 40.7 2.3 6e-05 21.7 0.1 3.0 2 1 1 3 3 3 3 Nitrogen Permease regulator of amino acid transport activity 3 Afi1 PF07792.7 EGC38526.1 - 0.0008 19.4 0.1 0.0023 17.9 0.0 1.7 2 0 0 2 2 2 1 Docking domain of Afi1 for Arf3 in vesicle trafficking cwf21 PF08312.7 EGC38527.1 - 0.017 14.9 3.2 0.017 14.9 2.2 3.2 3 0 0 3 3 3 0 cwf21 domain Calreticulin PF00262.13 EGC38528.1 - 4.6e-81 272.3 4.7 5.2e-81 272.1 3.3 1.0 1 0 0 1 1 1 1 Calreticulin family Mem_trans PF03547.13 EGC38529.1 - 0.0061 14.9 0.4 0.0082 14.4 0.3 1.2 1 0 0 1 1 1 1 Membrane transport protein Microcin PF03526.8 EGC38529.1 - 0.068 12.7 0.1 0.15 11.7 0.1 1.6 1 0 0 1 1 1 0 Colicin E1 (microcin) immunity protein SID-1_RNA_chan PF13965.1 EGC38529.1 - 0.25 9.4 3.1 0.28 9.3 2.2 1.1 1 0 0 1 1 1 0 dsRNA-gated channel SID-1 Moricin PF06451.6 EGC38529.1 - 1.7 8.2 3.9 1 8.8 0.4 2.1 2 0 0 2 2 2 0 Moricin FAM176 PF14851.1 EGC38529.1 - 2.8 7.6 6.5 0.35 10.5 0.3 2.3 1 1 0 2 2 2 0 FAM176 family Di19_C PF14571.1 EGC38529.1 - 4.3 7.7 10.2 0.73 10.1 3.5 2.0 2 0 0 2 2 2 0 Stress-induced protein Di19, C-terminal NAP PF00956.13 EGC38530.1 - 1e-14 54.2 25.4 1.6e-14 53.6 17.6 1.2 1 0 0 1 1 1 1 Nucleosome assembly protein (NAP) RuvC PF02075.12 EGC38530.1 - 0.14 11.9 0.7 0.42 10.4 0.2 2.0 2 0 0 2 2 2 0 Crossover junction endodeoxyribonuclease RuvC Nucleic_acid_bd PF13820.1 EGC38530.1 - 0.19 11.3 2.6 0.16 11.5 0.3 1.9 2 1 0 2 2 2 0 Putative nucleic acid-binding region Pico_P1A PF02226.11 EGC38530.1 - 3.8 7.3 9.9 1.4 8.7 2.1 2.8 3 0 0 3 3 3 0 Picornavirus coat protein (VP4) RNA_pol_Rbc25 PF08292.7 EGC38530.1 - 6.3 7.0 13.0 0.25 11.5 4.0 2.3 1 1 0 2 2 2 0 RNA polymerase III subunit Rpc25 Kelch_4 PF13418.1 EGC38531.1 - 1.7e-33 114.1 9.1 1e-08 34.7 0.0 6.7 5 2 1 6 6 6 6 Galactose oxidase, central domain Kelch_5 PF13854.1 EGC38531.1 - 6.3e-33 112.2 18.5 1.7e-06 27.8 0.0 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_3 PF13415.1 EGC38531.1 - 4.7e-29 99.8 11.2 1.6e-05 24.9 0.0 8.7 7 2 0 7 7 7 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC38531.1 - 1.7e-26 91.2 17.7 1.5e-07 31.2 0.2 6.6 4 2 2 6 6 6 5 Kelch motif BTB PF00651.26 EGC38531.1 - 6.6e-25 87.2 0.8 2.1e-23 82.4 0.1 2.5 1 1 1 2 2 2 1 BTB/POZ domain Kelch_1 PF01344.20 EGC38531.1 - 2.2e-24 84.6 23.9 1.3e-08 34.2 0.6 6.7 6 1 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC38531.1 - 5.2e-17 60.8 21.1 6.4e-05 22.5 0.1 7.6 7 1 0 7 7 7 4 Kelch motif BACK PF07707.10 EGC38531.1 - 0.0087 15.8 0.4 1.2 9.0 0.0 2.5 2 0 0 2 2 2 1 BTB And C-terminal Kelch PLDc PF00614.17 EGC38531.1 - 1.7 8.5 4.2 8.7 6.3 0.6 2.5 2 0 0 2 2 2 0 Phospholipase D Active site motif OATP PF03137.15 EGC38533.1 - 0.022 12.8 4.8 0.23 9.4 1.2 2.1 2 0 0 2 2 2 0 Organic Anion Transporter Polypeptide (OATP) family Oxidored_q3 PF00499.15 EGC38533.1 - 0.054 13.2 0.8 0.096 12.4 0.2 1.7 2 0 0 2 2 2 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF2500 PF10694.4 EGC38533.1 - 0.14 12.2 4.7 0.37 10.8 3.3 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF2500) Nucleoside_tran PF01733.13 EGC38533.1 - 0.15 11.2 1.9 0.11 11.5 0.3 1.5 2 0 0 2 2 2 0 Nucleoside transporter Ctr PF04145.10 EGC38533.1 - 5.7 6.9 7.9 13 5.8 5.4 2.0 1 1 0 1 1 1 0 Ctr copper transporter family PAT1 PF09770.4 EGC38533.1 - 8 4.5 35.0 10 4.1 24.3 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Voltage_CLC PF00654.15 EGC38534.1 - 1.3e-97 326.9 26.0 2.4e-97 326.1 14.0 2.1 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EGC38534.1 - 6.8e-14 51.3 0.5 3.3e-06 26.7 0.0 2.6 2 0 0 2 2 2 2 CBS domain UCR_Fe-S_N PF10399.4 EGC38534.1 - 0.005 15.9 0.7 0.011 14.8 0.5 1.6 1 0 0 1 1 1 1 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal TAT_signal PF10518.4 EGC38534.1 - 0.0058 16.5 1.7 0.0058 16.5 1.2 2.9 3 0 0 3 3 3 1 TAT (twin-arginine translocation) pathway signal sequence SAP PF02037.22 EGC38535.1 - 5.8e-11 41.6 0.1 2.1e-08 33.4 0.0 2.7 2 0 0 2 2 2 2 SAP domain DUF3185 PF11381.3 EGC38536.1 - 0.44 10.3 2.9 2.3 8.0 0.5 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) Dor1 PF04124.7 EGC38537.1 - 4.5e-69 232.5 16.7 4.5e-69 232.5 11.6 3.0 3 1 0 3 3 3 1 Dor1-like family Nucleoplasmin PF03066.10 EGC38538.1 - 0.11 12.0 16.4 0.49 9.9 11.4 2.1 1 1 0 1 1 1 0 Nucleoplasmin PAT1 PF09770.4 EGC38538.1 - 3.2 5.8 34.7 4.1 5.5 24.0 1.2 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Zip PF02535.17 EGC38539.1 - 1 8.2 15.2 1.6 7.7 10.5 1.3 1 1 0 1 1 1 0 ZIP Zinc transporter FNIP PF05725.7 EGC38540.1 - 1.3e-61 204.2 42.0 3.1e-14 52.6 0.0 14.0 6 4 6 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC38540.1 - 0.022 14.7 4.9 10 6.1 0.0 5.3 6 0 0 6 6 6 0 Protein of unknown function (DUF1769) LAGLIDADG_1 PF00961.14 EGC38542.1 - 2.1e-09 37.8 4.6 7.9e-05 23.1 0.1 3.2 3 0 0 3 3 3 2 LAGLIDADG endonuclease DUF1312 PF07009.6 EGC38542.1 - 0.068 12.9 0.0 0.16 11.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF1312) Rsa3 PF14615.1 EGC38543.1 - 2.1e-16 58.9 0.8 5e-16 57.7 0.5 1.7 1 0 0 1 1 1 1 Ribosome-assembly protein 3 DSPc PF00782.15 EGC38544.1 - 3.3e-20 72.0 0.5 5.8e-20 71.2 0.3 1.4 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain PTPlike_phytase PF14566.1 EGC38544.1 - 1.8e-05 24.8 0.0 2.9e-05 24.1 0.0 1.3 1 0 0 1 1 1 1 Inositol hexakisphosphate CDKN3 PF05706.7 EGC38544.1 - 8.5e-05 22.0 0.7 0.00012 21.6 0.0 1.6 2 0 0 2 2 2 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase PF00102.22 EGC38544.1 - 0.00093 18.6 0.7 0.00093 18.6 0.5 1.7 2 1 0 2 2 2 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGC38544.1 - 0.0027 17.0 0.0 0.0052 16.1 0.0 1.4 1 0 0 1 1 1 1 Tyrosine phosphatase family Y_phosphatase3 PF13350.1 EGC38544.1 - 0.0035 17.6 0.0 0.0056 16.9 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family MscS_TM PF12794.2 EGC38544.1 - 0.016 13.8 0.5 0.024 13.2 0.4 1.3 1 0 0 1 1 1 0 Mechanosensitive ion channel inner membrane domain 1 DUF1442 PF07279.6 EGC38544.1 - 0.086 11.9 0.0 0.12 11.4 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1442) PIP5K PF01504.13 EGC38545.1 - 2.4e-62 210.3 4.2 6.1e-62 208.9 2.9 1.6 1 1 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase DUF2146 PF10220.4 EGC38546.1 - 3.6e-45 154.3 27.2 9.5e-30 103.3 0.1 3.8 3 1 1 4 4 4 3 Uncharacterized conserved protein (DUF2146) CDI PF02234.14 EGC38546.1 - 0.055 13.2 0.0 0.19 11.5 0.0 1.9 1 0 0 1 1 1 0 Cyclin-dependent kinase inhibitor Neur_chan_memb PF02932.11 EGC38546.1 - 0.28 11.0 4.3 0.45 10.3 1.5 2.1 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region POX PF07526.6 EGC38546.1 - 8.9 6.5 8.4 7.7 6.7 2.6 2.5 2 0 0 2 2 2 0 Associated with HOX CH PF00307.26 EGC38547.1 - 1e-19 70.5 0.0 1.1e-19 70.4 0.0 1.0 1 0 0 1 1 1 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC38547.1 - 6.6e-10 38.4 0.0 8.9e-10 38.0 0.0 1.2 1 0 0 1 1 1 1 CAMSAP CH domain ArgK PF03308.11 EGC38549.1 - 1.7e-88 295.9 0.0 2e-88 295.6 0.0 1.1 1 0 0 1 1 1 1 ArgK protein cobW PF02492.14 EGC38549.1 - 5e-07 29.3 0.2 7.9e-06 25.4 0.2 2.4 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain ATP_bind_1 PF03029.12 EGC38549.1 - 8.4e-06 25.4 0.4 3.4e-05 23.5 0.0 2.1 2 0 0 2 2 2 1 Conserved hypothetical ATP binding protein AAA_17 PF13207.1 EGC38549.1 - 6.9e-05 23.6 0.3 0.0002 22.1 0.0 2.1 2 0 0 2 2 1 1 AAA domain NTPase_1 PF03266.10 EGC38549.1 - 0.00097 18.8 0.1 0.0024 17.6 0.1 1.7 1 0 0 1 1 1 1 NTPase MobB PF03205.9 EGC38549.1 - 0.0015 18.2 0.1 0.0059 16.3 0.0 2.1 2 0 0 2 2 1 1 Molybdopterin guanine dinucleotide synthesis protein B DAP3 PF10236.4 EGC38549.1 - 0.0034 16.3 2.8 0.064 12.1 0.0 3.0 2 1 1 3 3 3 1 Mitochondrial ribosomal death-associated protein 3 AAA_10 PF12846.2 EGC38549.1 - 0.0058 16.1 0.1 0.02 14.3 0.0 1.5 1 1 0 1 1 1 1 AAA-like domain AAA_18 PF13238.1 EGC38549.1 - 0.0062 16.8 0.1 0.0062 16.8 0.1 2.7 3 0 0 3 3 3 1 AAA domain AAA_33 PF13671.1 EGC38549.1 - 0.0086 15.9 0.0 0.016 15.1 0.0 1.5 1 0 0 1 1 1 1 AAA domain ABC_tran PF00005.22 EGC38549.1 - 0.018 15.3 1.3 0.03 14.6 0.2 1.9 1 1 1 2 2 2 0 ABC transporter AAA_30 PF13604.1 EGC38549.1 - 0.022 14.3 0.0 0.035 13.6 0.0 1.3 1 0 0 1 1 1 0 AAA domain Thymidylate_kin PF02223.12 EGC38549.1 - 0.025 13.9 0.2 0.07 12.5 0.0 1.9 2 0 0 2 2 1 0 Thymidylate kinase AAA_29 PF13555.1 EGC38549.1 - 0.027 13.9 0.0 0.052 13.0 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC38549.1 - 0.03 14.3 0.0 0.16 11.9 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGC38549.1 - 0.054 12.5 0.1 0.11 11.5 0.0 1.5 1 0 0 1 1 1 0 Zeta toxin PRK PF00485.13 EGC38549.1 - 0.056 12.9 0.1 0.14 11.6 0.1 1.7 1 0 0 1 1 1 0 Phosphoribulokinase / Uridine kinase family AAA PF00004.24 EGC38549.1 - 0.06 13.5 0.0 0.17 12.0 0.0 1.8 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) CbiA PF01656.18 EGC38549.1 - 0.063 12.6 0.4 0.21 10.9 0.0 2.0 2 0 0 2 2 2 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_24 PF13479.1 EGC38549.1 - 0.066 12.7 0.8 0.11 12.0 0.1 1.8 2 0 0 2 2 2 0 AAA domain IstB_IS21 PF01695.12 EGC38549.1 - 0.068 12.5 0.0 0.19 11.1 0.0 1.7 2 0 0 2 2 2 0 IstB-like ATP binding protein APS_kinase PF01583.15 EGC38549.1 - 0.068 12.8 0.0 0.35 10.5 0.0 2.1 1 1 1 2 2 2 0 Adenylylsulphate kinase RNA_helicase PF00910.17 EGC38549.1 - 0.079 13.1 0.1 0.36 11.0 0.0 2.2 1 0 0 1 1 1 0 RNA helicase AAA_28 PF13521.1 EGC38549.1 - 0.086 12.8 0.5 0.19 11.7 0.1 1.7 2 0 0 2 2 1 0 AAA domain AAA_22 PF13401.1 EGC38549.1 - 0.098 12.7 0.2 0.29 11.2 0.0 1.9 2 0 0 2 2 1 0 AAA domain AAA_14 PF13173.1 EGC38549.1 - 0.13 12.1 2.0 0.4 10.5 0.0 2.6 2 1 1 3 3 3 0 AAA domain MMR_HSR1 PF01926.18 EGC38549.1 - 0.19 11.7 3.1 0.17 11.8 0.4 2.5 2 1 0 2 2 2 0 50S ribosome-binding GTPase p450 PF00067.17 EGC38549.1 - 0.42 9.0 6.8 0.08 11.4 1.4 1.8 2 0 0 2 2 2 0 Cytochrome P450 Sec5 PF15469.1 EGC38549.1 - 1 9.0 11.6 0.38 10.4 3.3 2.4 2 1 1 3 3 3 0 Exocyst complex component Sec5 AMP-binding PF00501.23 EGC38550.1 - 7.8e-69 232.0 0.0 9.3e-69 231.8 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC38550.1 - 2.4e-08 34.8 0.0 4.3e-08 33.9 0.0 1.5 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain CLASP_N PF12348.3 EGC38551.1 - 4.2e-50 170.2 5.4 4.2e-50 170.2 3.7 1.9 2 0 0 2 2 2 1 CLASP N terminal HEAT_2 PF13646.1 EGC38551.1 - 0.15 12.3 0.2 2 8.7 0.0 2.9 2 1 0 2 2 2 0 HEAT repeats PCI PF01399.22 EGC38552.1 - 7.3e-11 42.3 0.9 1.4e-10 41.4 0.6 1.5 1 0 0 1 1 1 1 PCI domain Abhydrolase_3 PF07859.8 EGC38553.1 - 3.3e-45 154.2 0.0 4.1e-45 153.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGC38553.1 - 2.1e-12 46.3 0.4 3.1e-12 45.8 0.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF2424) Abhydrolase_5 PF12695.2 EGC38553.1 - 1.8e-06 27.7 0.0 2.3e-06 27.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family COesterase PF00135.23 EGC38553.1 - 3.7e-06 25.9 0.2 0.001 17.9 0.0 2.4 2 1 0 2 2 2 2 Carboxylesterase family Esterase PF00756.15 EGC38553.1 - 0.0056 16.1 0.0 0.44 9.9 0.0 2.2 2 0 0 2 2 2 1 Putative esterase AXE1 PF05448.7 EGC38553.1 - 0.0091 14.5 0.0 0.016 13.7 0.0 1.3 1 0 0 1 1 1 1 Acetyl xylan esterase (AXE1) Abhydrolase_6 PF12697.2 EGC38553.1 - 0.093 12.5 0.0 0.13 12.1 0.0 1.2 1 0 0 1 1 1 0 Alpha/beta hydrolase family Sec7_N PF12783.2 EGC38554.1 - 3.8e-33 114.2 1.2 3.8e-33 114.2 0.8 6.1 7 0 0 7 7 7 3 Guanine nucleotide exchange factor in Golgi transport N-terminal DUF1981 PF09324.5 EGC38554.1 - 9.4e-06 25.0 0.7 9.4e-06 25.0 0.5 4.9 5 0 0 5 5 5 1 Domain of unknown function (DUF1981) Sec8_exocyst PF04048.9 EGC38555.1 - 0.021 14.4 28.6 0.015 14.9 12.6 2.6 1 1 1 2 2 2 0 Sec8 exocyst complex component specific domain Ras PF00071.17 EGC38556.1 - 2.5e-12 46.4 11.3 2.1e-05 23.9 7.8 3.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC38556.1 - 3.2e-07 30.8 0.2 3e-06 27.7 0.0 2.6 2 1 0 2 2 2 1 Miro-like protein AAA_17 PF13207.1 EGC38556.1 - 3.1 8.6 7.1 46 4.8 5.0 2.7 1 1 0 1 1 1 0 AAA domain Nucleoside_tran PF01733.13 EGC38557.1 - 0.12 11.5 0.4 0.21 10.6 0.3 1.4 1 0 0 1 1 1 0 Nucleoside transporter OATP PF03137.15 EGC38557.1 - 0.23 9.4 0.7 0.41 8.6 0.5 1.4 1 0 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Serinc PF03348.10 EGC38557.1 - 2.5 6.6 8.0 0.035 12.8 0.6 1.4 2 0 0 2 2 2 0 Serine incorporator (Serinc) Mem_trans PF03547.13 EGC38557.1 - 8 4.6 9.8 0.074 11.3 1.4 1.5 2 0 0 2 2 2 0 Membrane transport protein EamA PF00892.15 EGC38558.1 - 3.2e-11 43.3 32.4 4.7e-06 26.6 3.9 3.0 3 0 0 3 3 3 2 EamA-like transporter family CENP-B_dimeris PF09026.5 EGC38558.1 - 0.01 16.0 2.8 0.18 12.0 0.6 2.6 2 1 0 2 2 2 0 Centromere protein B dimerisation domain Med17 PF10156.4 EGC38558.1 - 0.013 13.7 6.5 0.075 11.2 0.1 2.0 2 0 0 2 2 2 0 Subunit 17 of Mediator complex Pex14_N PF04695.8 EGC38558.1 - 0.05 13.6 2.8 0.27 11.2 0.0 2.5 3 0 0 3 3 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region ETRAMP PF09716.5 EGC38558.1 - 0.34 10.8 7.7 2.6 8.0 0.9 3.2 2 0 0 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) DUF3671 PF12420.3 EGC38558.1 - 0.39 10.6 12.9 1.1 9.2 0.1 3.9 3 1 0 3 3 3 0 Protein of unknown function DUF2370 PF10176.4 EGC38558.1 - 0.46 9.7 3.9 0.35 10.1 0.3 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) GCIP PF13324.1 EGC38558.1 - 1 8.5 5.4 3.5 6.7 0.1 2.2 2 0 0 2 2 2 0 Grap2 and cyclin-D-interacting DUF1673 PF07895.6 EGC38558.1 - 1.3 8.4 16.3 7.4 6.0 5.4 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) AtpR PF12966.2 EGC38558.1 - 2 8.6 10.8 1.4 9.0 3.0 2.7 2 1 0 2 2 2 0 N-ATPase, AtpR subunit DUF230 PF03003.11 EGC38558.1 - 3.2 7.3 12.4 2.7 7.5 4.1 2.4 2 0 0 2 2 2 0 Poxvirus proteins of unknown function PsaM PF07465.8 EGC38558.1 - 3.5 7.3 6.2 0.86 9.2 0.2 2.4 2 0 0 2 2 2 0 Photosystem I protein M (PsaM) DUF1777 PF08648.7 EGC38559.1 - 0.0003 20.5 40.1 0.00075 19.2 24.2 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) MSA-2c PF12238.3 EGC38559.1 - 0.011 15.3 5.2 0.011 15.3 3.6 1.7 2 0 0 2 2 2 0 Merozoite surface antigen 2c Med19 PF10278.4 EGC38559.1 - 0.026 14.2 1.2 0.026 14.2 0.9 3.1 2 2 1 3 3 3 0 Mediator of RNA pol II transcription subunit 19 DUF1509 PF07420.6 EGC38559.1 - 0.13 11.4 14.8 0.2 10.9 10.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1509) LIM_bind PF01803.11 EGC38559.1 - 0.22 10.6 3.6 0.37 9.8 2.5 1.3 1 0 0 1 1 1 0 LIM-domain binding protein Pex14_N PF04695.8 EGC38559.1 - 1.5 8.8 9.2 0.23 11.4 3.8 1.8 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region DUF605 PF04652.11 EGC38560.1 - 1.1e-86 291.6 74.7 3.6e-67 227.3 11.6 3.0 1 1 2 3 3 3 3 Vta1 like V_ATPase_I PF01496.14 EGC38560.1 - 0.038 11.8 10.7 0.062 11.1 7.4 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family ATG16 PF08614.6 EGC38560.1 - 0.067 13.0 22.9 2 8.1 12.6 2.3 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) Phage_int_SAM_5 PF13102.1 EGC38560.1 - 0.11 12.4 14.7 0.019 14.9 7.2 1.9 2 0 0 2 2 2 0 Phage integrase SAM-like domain DUF2400 PF09674.5 EGC38560.1 - 0.34 10.5 6.2 0.58 9.8 4.3 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2400) IncA PF04156.9 EGC38560.1 - 2 7.9 17.7 1.3 8.5 10.1 2.0 2 0 0 2 2 2 0 IncA protein Atg14 PF10186.4 EGC38560.1 - 3.2 6.5 18.3 6.9 5.5 12.7 1.5 1 0 0 1 1 1 0 UV radiation resistance protein and autophagy-related subunit 14 DUF2852 PF11014.3 EGC38560.1 - 5 7.1 9.8 13 5.7 6.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2852) LRR_4 PF12799.2 EGC38561.1 - 6.5 6.5 12.8 3.3 7.4 2.2 4.0 3 2 0 3 3 3 0 Leucine Rich repeats (2 copies) Melibiase PF02065.13 EGC38562.1 - 2.7e-21 75.7 0.4 1e-16 60.6 0.0 2.5 1 1 0 2 2 2 2 Melibiase HSP20 PF00011.16 EGC38563.1 - 0.0015 18.3 0.0 0.0035 17.1 0.0 1.6 1 0 0 1 1 1 1 Hsp20/alpha crystallin family GBP PF02263.14 EGC38563.1 - 0.024 13.7 0.0 0.045 12.8 0.0 1.4 1 0 0 1 1 1 0 Guanylate-binding protein, N-terminal domain Pyr_redox_2 PF07992.9 EGC38564.1 - 4e-23 82.3 0.5 1.9e-12 47.5 0.0 3.8 2 1 1 3 3 3 3 Pyridine nucleotide-disulphide oxidoreductase Pyr_redox PF00070.22 EGC38564.1 - 5.2e-10 39.5 0.2 2.8e-09 37.2 0.1 2.3 3 0 0 3 3 3 1 Pyridine nucleotide-disulphide oxidoreductase DUF4659 PF15558.1 EGC38564.1 - 0.032 12.8 0.1 0.057 12.0 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4659) KduI PF04962.7 EGC38564.1 - 0.061 12.4 0.1 0.097 11.7 0.0 1.2 1 0 0 1 1 1 0 KduI/IolB family Pyr_redox_3 PF13738.1 EGC38564.1 - 0.074 13.1 0.4 2.2 8.2 0.0 3.1 1 1 2 3 3 2 0 Pyridine nucleotide-disulphide oxidoreductase Imm9 PF15561.1 EGC38565.1 - 0.026 14.1 2.2 0.028 13.9 1.5 1.2 1 0 0 1 1 1 0 Immunity protein 9 DUF3526 PF12040.3 EGC38565.1 - 0.92 9.6 8.8 0.74 9.9 5.3 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF3526) Mu-like_Pro PF10123.4 EGC38565.1 - 1.4 8.2 7.1 1.6 8.1 4.9 1.0 1 0 0 1 1 1 0 Mu-like prophage I protein Suf PF05843.9 EGC38565.1 - 2.7 7.6 11.3 2.8 7.5 7.8 1.2 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) 5_3_exonuc PF01367.15 EGC38565.1 - 3.7 7.8 5.8 6 7.1 2.0 1.9 1 1 1 2 2 2 0 5'-3' exonuclease, C-terminal SAM fold Gti1_Pac2 PF09729.4 EGC38565.1 - 3.7 7.3 5.5 3.9 7.3 3.8 1.0 1 0 0 1 1 1 0 Gti1/Pac2 family MLANA PF14991.1 EGC38565.1 - 6.1 6.8 5.8 22 5.1 1.0 2.0 1 1 1 2 2 2 0 Protein melan-A DUF1104 PF06518.6 EGC38565.1 - 7 6.8 7.2 0.49 10.5 0.5 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF1104) Peptidase_C93 PF06035.6 EGC38567.1 - 1 8.7 6.0 0.95 8.8 4.2 1.1 1 0 0 1 1 1 0 Bacterial transglutaminase-like cysteine proteinase BTLCP DNA_pol_B PF00136.16 EGC38569.1 - 1.5e-88 297.6 0.0 5.4e-88 295.8 0.0 2.0 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGC38569.1 - 8.3e-20 70.8 24.5 6.9e-13 48.1 3.1 4.3 4 0 0 4 4 4 2 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGC38569.1 - 3.3e-12 46.2 8.2 1.2e-11 44.4 5.7 2.1 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta adh_short PF00106.20 EGC38570.1 - 9.5e-11 41.8 0.1 3.2e-09 36.9 0.1 2.0 1 1 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC38570.1 - 2e-06 27.7 0.0 4.4e-06 26.6 0.0 1.6 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGC38570.1 - 0.0036 16.7 0.0 0.017 14.5 0.0 1.9 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGC38570.1 - 0.02 13.7 0.0 0.037 12.9 0.0 1.6 1 1 0 1 1 1 0 RmlD substrate binding domain NmrA PF05368.8 EGC38570.1 - 0.073 12.3 0.0 0.11 11.7 0.0 1.2 1 0 0 1 1 1 0 NmrA-like family Semialdhyde_dh PF01118.19 EGC38570.1 - 0.095 13.0 0.0 0.14 12.4 0.0 1.3 1 0 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain KR PF08659.5 EGC38570.1 - 0.1 12.2 0.0 5.5 6.6 0.0 2.2 1 1 1 2 2 2 0 KR domain Exo_endo_phos PF03372.18 EGC38571.1 - 1.8e-05 24.8 0.0 0.00012 22.1 0.0 2.1 2 0 0 2 2 2 1 Endonuclease/Exonuclease/phosphatase family Sin_N PF04801.8 EGC38572.1 - 3.8e-109 365.3 9.3 4.9e-107 358.3 4.2 2.1 2 0 0 2 2 2 2 Sin-like protein conserved region Cna_B PF05738.8 EGC38572.1 - 0.0086 15.8 1.4 0.031 14.0 0.9 2.0 1 0 0 1 1 1 1 Cna protein B-type domain Actino_peptide PF14408.1 EGC38572.1 - 1.1 9.2 8.3 2.6 8.0 5.8 1.6 1 0 0 1 1 1 0 Ribosomally synthesized peptide in actinomycetes Erf4 PF10256.4 EGC38573.1 - 1.8e-10 40.6 0.1 2e-08 34.0 0.0 2.2 2 0 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Yip1 PF04893.12 EGC38573.1 - 0.0039 16.7 0.0 0.0055 16.2 0.0 1.2 1 0 0 1 1 1 1 Yip1 domain zf-DHHC PF01529.15 EGC38573.1 - 0.023 14.0 1.0 0.031 13.6 0.1 1.6 1 1 1 2 2 2 0 DHHC palmitoyltransferase FtsX PF02687.16 EGC38573.1 - 0.033 13.9 0.9 0.05 13.3 0.6 1.2 1 0 0 1 1 1 0 FtsX-like permease family Tetraspannin PF00335.15 EGC38573.1 - 0.16 11.2 6.2 0.033 13.4 1.3 1.9 2 0 0 2 2 2 0 Tetraspanin family DUF4234 PF14018.1 EGC38573.1 - 0.23 11.2 1.2 11 5.7 0.3 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4234) YrhK PF14145.1 EGC38573.1 - 0.59 9.8 4.9 9.8 5.9 0.0 2.4 2 0 0 2 2 2 0 YrhK-like protein ABC2_membrane_4 PF12730.2 EGC38573.1 - 1.2 8.2 7.6 2.4 7.2 4.1 1.7 1 1 0 1 1 1 0 ABC-2 family transporter protein DUF3185 PF11381.3 EGC38573.1 - 2 8.2 5.4 6.9 6.5 0.8 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) FixQ PF05545.6 EGC38573.1 - 2 8.0 5.4 0.96 9.1 0.9 2.2 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ FNIP PF05725.7 EGC38574.1 - 4.1e-198 641.2 107.5 2.6e-16 59.2 0.7 12.1 6 2 10 16 16 16 16 FNIP Repeat DUF1769 PF08588.5 EGC38574.1 - 5.9e-06 26.1 39.3 0.59 10.1 0.1 12.4 4 4 11 15 15 15 5 Protein of unknown function (DUF1769) LRR_6 PF13516.1 EGC38574.1 - 2.8 8.3 45.9 41 4.6 0.1 16.2 18 1 3 21 21 21 0 Leucine Rich repeat PAXIP1_C PF15364.1 EGC38575.1 - 0.011 15.6 3.4 0.011 15.6 2.3 2.2 2 0 0 2 2 2 0 PAXIP1-associated-protein-1 C term PTIP binding protein Mucin PF01456.12 EGC38575.1 - 0.063 13.0 13.4 0.046 13.5 5.6 2.3 2 0 0 2 2 2 0 Mucin-like glycoprotein LRR_4 PF12799.2 EGC38576.1 - 2.1e-59 196.3 76.9 9.1e-09 34.7 1.5 13.2 6 3 8 14 14 14 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC38576.1 - 6.4e-44 147.5 57.7 1.5e-08 34.2 1.7 9.3 3 3 9 12 12 12 10 Leucine rich repeat LRR_1 PF00560.28 EGC38576.1 - 3.5e-42 135.9 60.9 0.00069 19.2 0.1 19.4 20 0 0 20 20 20 13 Leucine Rich Repeat LRR_7 PF13504.1 EGC38576.1 - 8.6e-24 79.3 48.6 0.081 13.1 0.1 18.1 19 0 0 19 19 19 7 Leucine rich repeat LRR_6 PF13516.1 EGC38576.1 - 8.6e-06 25.3 63.5 0.2 11.8 0.1 15.6 15 4 3 18 18 18 5 Leucine Rich repeat LRRNT PF01462.13 EGC38576.1 - 0.0054 16.1 0.8 1.6 8.3 0.0 4.8 5 0 0 5 5 5 1 Leucine rich repeat N-terminal domain LRR_9 PF14580.1 EGC38576.1 - 0.029 13.9 17.3 0.077 12.5 0.4 4.1 3 1 1 4 4 4 0 Leucine-rich repeat DUF2036 PF09724.4 EGC38577.1 - 4.2e-84 282.4 8.6 6.8e-84 281.7 6.0 1.3 1 1 0 1 1 1 1 Uncharacterized conserved protein (DUF2036) HTH_Mga PF08280.6 EGC38577.1 - 0.0018 18.0 2.7 0.0027 17.4 0.8 2.2 1 1 0 1 1 1 1 M protein trans-acting positive regulator (MGA) HTH domain Defensin_propep PF00879.13 EGC38578.1 - 0.38 10.7 4.4 0.56 10.1 3.0 1.2 1 0 0 1 1 1 0 Defensin propeptide DUF998 PF06197.8 EGC38580.1 - 1.8e-07 30.6 0.0 4.3e-07 29.4 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF998) Cation_ATPase_C PF00689.16 EGC38580.1 - 0.2 11.1 9.1 0.12 11.8 4.6 1.8 1 1 1 2 2 2 0 Cation transporting ATPase, C-terminus DUF3566 PF12089.3 EGC38580.1 - 0.24 11.4 2.8 4.4 7.3 0.0 2.8 3 0 0 3 3 3 0 Transmembrane domain of unknown function (DUF3566) DUF2975 PF11188.3 EGC38580.1 - 0.34 10.6 8.9 0.13 11.9 3.2 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF2975) DUF1705 PF08019.7 EGC38580.1 - 2 7.9 8.1 0.27 10.7 1.3 2.5 2 1 1 3 3 3 0 Domain of unknown function (DUF1705) Nucleoside_tran PF01733.13 EGC38580.1 - 3.5 6.6 12.6 0.87 8.6 1.0 2.7 2 1 0 2 2 2 0 Nucleoside transporter TMEM192 PF14802.1 EGC38580.1 - 4 6.2 8.3 5.3 5.8 0.3 3.0 4 0 0 4 4 4 0 TMEM192 family Tic20 PF09685.5 EGC38580.1 - 5.3 7.0 16.0 0.069 13.1 3.0 2.7 2 1 1 3 3 3 0 Tic20-like protein Paf67 PF10255.4 EGC38581.1 - 1.4e-126 422.7 15.4 2.4e-126 421.8 10.7 1.4 1 0 0 1 1 1 1 RNA polymerase I-associated factor PAF67 PCI PF01399.22 EGC38581.1 - 0.0023 18.1 2.6 0.0031 17.8 0.4 2.2 2 0 0 2 2 2 1 PCI domain TPR_2 PF07719.12 EGC38581.1 - 0.0049 16.6 0.1 0.024 14.5 0.1 2.2 2 0 0 2 2 2 1 Tetratricopeptide repeat SAM_PNT PF02198.11 EGC38581.1 - 0.0088 15.7 0.7 0.027 14.2 0.1 2.2 2 0 0 2 2 2 1 Sterile alpha motif (SAM)/Pointed domain TPR_19 PF14559.1 EGC38581.1 - 0.017 15.4 0.1 4.3 7.7 0.0 3.1 3 0 0 3 3 3 0 Tetratricopeptide repeat p450 PF00067.17 EGC38582.1 - 3.8e-86 289.4 0.0 4.3e-86 289.2 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Peptidase_M90 PF06167.7 EGC38582.1 - 0.057 12.7 0.0 0.11 11.9 0.0 1.4 1 0 0 1 1 1 0 Glucose-regulated metallo-peptidase M90 YfcL PF08891.6 EGC38583.1 - 0.0077 16.1 0.8 0.0077 16.1 0.5 3.7 4 0 0 4 4 4 1 YfcL protein SLAM PF06214.6 EGC38583.1 - 0.013 15.4 0.7 0.013 15.4 0.5 3.0 3 1 1 4 4 4 0 Signaling lymphocytic activation molecule (SLAM) protein Mem_trans PF03547.13 EGC38583.1 - 0.05 11.8 4.3 0.13 10.5 3.0 1.7 1 0 0 1 1 1 0 Membrane transport protein FNIP PF05725.7 EGC38584.1 - 2.4e-81 267.4 87.5 4.1e-11 42.6 2.8 13.3 8 3 4 13 13 13 12 FNIP Repeat Pkinase PF00069.20 EGC38584.1 - 8.7e-45 152.8 4.0 6.2e-43 146.8 1.5 2.1 1 1 1 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38584.1 - 1.1e-29 103.2 0.1 8.3e-28 97.1 0.0 2.1 1 1 1 2 2 2 2 Protein tyrosine kinase Kdo PF06293.9 EGC38584.1 - 0.011 14.8 0.0 0.019 14.0 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family DUF2435 PF10363.4 EGC38584.1 - 0.017 15.0 0.0 0.045 13.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2435) APH PF01636.18 EGC38584.1 - 0.025 14.3 0.2 0.04 13.6 0.1 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family SQS_PSY PF00494.14 EGC38585.1 - 7e-39 133.7 0.0 9e-39 133.3 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase RNA_pol_Rpc82 PF05645.8 EGC38585.1 - 0.047 13.2 1.6 0.053 13.0 0.3 1.6 1 1 0 2 2 2 0 RNA polymerase III subunit RPC82 Ketoacyl-synt_C PF02801.17 EGC38587.1 - 6.7e-25 87.2 0.0 2.2e-24 85.5 0.0 1.9 3 0 0 3 3 3 1 Beta-ketoacyl synthase, C-terminal domain ketoacyl-synt PF00109.21 EGC38587.1 - 4.9e-20 72.0 0.0 8e-20 71.3 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Methyltransf_12 PF08242.7 EGC38587.1 - 3.5e-19 69.0 0.0 3.5e-19 69.0 0.0 2.7 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.1 EGC38587.1 - 1.7e-10 40.5 0.0 2.5e-10 40.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_23 PF13489.1 EGC38587.1 - 1.4e-08 34.6 0.0 6.7e-08 32.4 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38587.1 - 3.5e-08 33.8 0.0 1.2e-07 32.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38587.1 - 3.5e-06 26.6 0.1 1.8e-05 24.3 0.1 2.2 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC38587.1 - 0.0066 15.5 0.0 0.012 14.6 0.0 1.5 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family NodS PF05401.6 EGC38587.1 - 0.0071 15.7 0.0 0.016 14.6 0.0 1.5 1 0 0 1 1 1 1 Nodulation protein S (NodS) Methyltransf_18 PF12847.2 EGC38587.1 - 0.0096 16.4 0.0 0.028 14.9 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Glyco_hydro_47 PF01532.15 EGC38588.1 - 6.9e-132 440.3 0.2 7.7e-132 440.1 0.1 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_76 PF03663.9 EGC38588.1 - 0.21 10.9 1.7 26 4.0 0.0 3.5 3 1 1 4 4 4 0 Glycosyl hydrolase family 76 ketoacyl-synt PF00109.21 EGC38589.1 - 2.6e-62 210.6 0.0 5.1e-62 209.6 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38589.1 - 8.9e-46 156.6 0.0 1.5e-45 155.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38589.1 - 1.3e-29 102.4 0.0 4.4e-29 100.7 0.0 1.9 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38589.1 - 1.5e-23 83.4 0.0 3.1e-23 82.3 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC38589.1 - 2.5e-20 72.7 3.3 6.3e-20 71.4 0.0 3.5 2 0 0 2 2 2 1 Methyltransferase domain PS-DH PF14765.1 EGC38589.1 - 5.6e-20 71.6 0.0 8.8e-20 71.0 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC38589.1 - 4.3e-15 56.0 0.0 7.4e-15 55.2 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38589.1 - 1.2e-08 35.8 0.0 2.7e-08 34.7 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38589.1 - 5.9e-07 29.2 0.1 1.3e-06 28.0 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38589.1 - 3.2e-06 27.5 0.1 1.8e-05 25.1 0.0 2.4 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38589.1 - 4.5e-06 26.4 0.0 1.5e-05 24.8 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC38589.1 - 9.7e-06 24.7 0.0 2.9e-05 23.1 0.0 1.7 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC38589.1 - 0.00024 21.6 0.0 0.0015 19.0 0.0 2.4 2 0 0 2 2 2 1 Methyltransferase domain Glyco_hydro_47 PF01532.15 EGC38590.1 - 4.5e-19 68.4 0.0 4.9e-19 68.3 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 ketoacyl-synt PF00109.21 EGC38591.1 - 9.2e-62 208.8 0.0 1.9e-61 207.7 0.0 1.5 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38591.1 - 1.5e-45 155.9 0.0 2.6e-45 155.1 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38591.1 - 1.4e-29 102.3 0.0 4.7e-29 100.6 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38591.1 - 7.1e-25 87.7 0.0 1.5e-24 86.6 0.0 1.5 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC38591.1 - 1.1e-20 74.0 0.0 1.6e-20 73.4 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EGC38591.1 - 1.9e-20 73.1 0.1 1.9e-20 73.1 0.0 4.1 4 0 0 4 4 2 1 Methyltransferase domain adh_short PF00106.20 EGC38591.1 - 1.8e-16 60.5 0.0 3.2e-16 59.7 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC38591.1 - 1.3e-08 34.7 0.0 3.4e-08 33.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC38591.1 - 3.8e-08 34.2 0.0 9.1e-08 33.0 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38591.1 - 3.9e-07 29.8 0.1 8.7e-07 28.6 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38591.1 - 4.6e-07 30.2 0.1 3.2e-06 27.5 0.0 2.6 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38591.1 - 5e-07 29.4 6.1 6.3e-06 25.8 0.0 4.5 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 EGC38591.1 - 1.2e-05 24.5 0.0 2.9e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC38591.1 - 0.00012 22.5 0.0 0.0024 18.4 0.0 2.8 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC38591.1 - 0.025 14.8 0.2 0.069 13.4 0.1 1.8 1 0 0 1 1 1 0 Phosphopantetheine attachment site TFIIA PF03153.8 EGC38593.1 - 1 9.2 19.4 1.3 8.8 13.5 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit AAA_23 PF13476.1 EGC38593.1 - 2.3 8.4 19.2 3.4 7.9 13.3 1.3 1 0 0 1 1 1 0 AAA domain zf-RING_2 PF13639.1 EGC38594.1 - 2.4e-11 43.2 8.0 3.6e-11 42.7 5.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC38594.1 - 2.2e-08 33.6 9.4 3.6e-08 32.9 6.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC38594.1 - 5e-08 32.4 6.0 7.5e-08 31.9 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38594.1 - 1.1e-06 28.5 9.0 1.6e-06 28.0 6.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC38594.1 - 1.8e-05 24.4 5.4 4.1e-05 23.3 3.7 1.6 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC38594.1 - 7.4e-05 22.7 7.8 0.00017 21.6 5.4 1.6 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC38594.1 - 0.00056 19.5 7.3 0.0011 18.7 5.1 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC38594.1 - 0.0019 17.7 10.2 0.0038 16.7 7.0 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain SET PF00856.23 EGC38594.1 - 0.058 13.7 1.9 0.066 13.5 1.3 1.1 1 0 0 1 1 1 0 SET domain Spore_coat_CotO PF14153.1 EGC38594.1 - 0.062 12.7 10.2 0.074 12.4 7.1 1.2 1 0 0 1 1 1 0 Spore coat protein CotO V_ATPase_I PF01496.14 EGC38594.1 - 0.16 9.8 4.9 0.15 9.9 3.4 1.0 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Ycf1 PF05758.7 EGC38594.1 - 0.23 9.1 7.7 0.22 9.1 5.4 1.0 1 0 0 1 1 1 0 Ycf1 Nop14 PF04147.7 EGC38594.1 - 0.33 8.8 19.4 0.32 8.8 13.5 1.0 1 0 0 1 1 1 0 Nop14-like family zf-RING_UBOX PF13445.1 EGC38594.1 - 0.35 10.6 4.1 1.4 8.7 2.8 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC38594.1 - 0.38 10.6 5.6 0.96 9.3 3.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger SAPS PF04499.10 EGC38594.1 - 0.48 9.0 5.5 0.46 9.0 3.8 1.0 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CDC45 PF02724.9 EGC38594.1 - 0.56 8.1 12.8 0.59 8.0 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein DUF2058 PF09831.4 EGC38594.1 - 0.74 9.6 12.0 1.1 9.1 8.4 1.3 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) DZR PF12773.2 EGC38594.1 - 0.84 9.5 7.8 1.5 8.6 4.4 2.0 1 1 0 1 1 1 0 Double zinc ribbon IBR PF01485.16 EGC38594.1 - 0.92 9.4 11.4 5.9 6.8 7.8 2.2 1 1 0 1 1 1 0 IBR domain Prok-RING_4 PF14447.1 EGC38594.1 - 1.2 8.7 9.4 4.1 7.0 6.5 1.9 1 1 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_3 PF14369.1 EGC38594.1 - 1.8 8.6 12.6 0.12 12.3 3.9 2.3 1 1 0 2 2 2 0 zinc-finger DUF342 PF03961.8 EGC38594.1 - 2.2 6.6 5.9 2.4 6.4 4.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF342) Peptidase_U57 PF05582.7 EGC38594.1 - 2.3 7.1 4.3 2.5 6.9 3.0 1.1 1 0 0 1 1 1 0 YabG peptidase U57 NARP1 PF12569.3 EGC38594.1 - 3.3 6.3 13.4 3.9 6.1 9.3 1.0 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 Mnd1 PF03962.10 EGC38594.1 - 3.6 7.1 15.2 4.3 6.9 10.6 1.1 1 0 0 1 1 1 0 Mnd1 family DUF1510 PF07423.6 EGC38594.1 - 3.9 6.7 14.9 4.6 6.5 10.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) zf-RING_6 PF14835.1 EGC38594.1 - 4.2 7.2 7.8 0.16 11.7 1.5 1.7 2 0 0 2 2 1 0 zf-RING of BARD1-type protein zf-HC5HC2H PF13771.1 EGC38594.1 - 4.8 7.3 9.2 5.6 7.1 5.5 1.8 1 1 1 2 2 2 0 PHD-like zinc-binding domain Vps39_2 PF10367.4 EGC38594.1 - 4.8 7.4 7.9 3.1 8.0 4.0 1.8 2 0 0 2 2 2 0 Vacuolar sorting protein 39 domain 2 SprA-related PF12118.3 EGC38594.1 - 5.3 6.2 14.9 6.2 6.0 10.4 1.1 1 0 0 1 1 1 0 SprA-related family YqfQ PF14181.1 EGC38594.1 - 5.4 7.0 11.3 7 6.6 7.8 1.2 1 0 0 1 1 1 0 YqfQ-like protein MAP7 PF05672.6 EGC38594.1 - 8.5 5.7 42.3 11 5.2 29.3 1.2 1 0 0 1 1 1 0 MAP7 (E-MAP-115) family DUF3987 PF13148.1 EGC38594.1 - 9.1 4.7 11.5 11 4.5 8.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3987) Sec62 PF03839.11 EGC38594.1 - 10 5.4 6.8 12 5.2 4.7 1.1 1 0 0 1 1 1 0 Translocation protein Sec62 FAM163 PF15069.1 EGC38595.1 - 0.059 13.9 0.1 0.21 12.1 0.1 1.9 1 0 0 1 1 1 0 FAM163 family zf-RING_2 PF13639.1 EGC38596.1 - 1.3e-09 37.7 8.7 2.8e-09 36.6 6.1 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38596.1 - 2.2e-08 33.6 7.4 4.1e-08 32.7 5.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38596.1 - 4.2e-07 29.5 11.1 1.1e-06 28.1 7.7 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38596.1 - 5.4e-06 26.3 10.1 1.3e-05 25.1 7.0 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38596.1 - 5.9e-05 22.6 8.7 0.00016 21.3 6.1 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC38596.1 - 0.00033 20.1 9.5 0.00076 19.0 6.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGC38596.1 - 0.00063 19.8 6.0 0.0018 18.3 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC38596.1 - 0.0026 17.5 8.7 0.011 15.6 6.0 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EGC38596.1 - 0.0082 15.6 7.7 0.017 14.6 5.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGC38596.1 - 0.021 14.5 1.8 0.044 13.5 1.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC38596.1 - 0.055 13.1 7.0 0.28 10.9 4.8 2.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC38596.1 - 0.12 12.2 1.5 0.25 11.2 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger Dapper PF15268.1 EGC38596.1 - 0.52 9.0 45.0 0.85 8.3 31.2 1.2 1 0 0 1 1 1 0 Dapper DZR PF12773.2 EGC38596.1 - 3 7.7 8.2 22 4.9 5.6 2.3 1 1 0 1 1 1 0 Double zinc ribbon DENN PF02141.16 EGC38597.1 - 9.9e-30 103.6 4.0 6e-26 91.3 0.1 3.2 2 1 0 2 2 2 2 DENN (AEX-3) domain uDENN PF03456.13 EGC38597.1 - 2.2e-08 33.9 1.2 4.2e-07 29.8 0.5 3.4 2 1 0 2 2 2 1 uDENN domain BCS1_N PF08740.6 EGC38598.1 - 1.1e-50 171.8 0.2 2.4e-50 170.7 0.1 1.6 1 0 0 1 1 1 1 BCS1 N terminal AAA PF00004.24 EGC38598.1 - 4.5e-16 59.2 0.1 5.5e-10 39.5 0.0 2.8 3 0 0 3 3 3 2 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC38598.1 - 0.00032 21.4 0.0 0.0011 19.7 0.0 1.9 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC38598.1 - 0.00068 19.6 0.0 0.0012 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGC38598.1 - 0.00093 18.1 0.0 0.0016 17.4 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_25 PF13481.1 EGC38598.1 - 0.00099 18.5 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC38598.1 - 0.0027 17.8 0.0 0.043 13.9 0.0 2.5 2 0 0 2 2 2 1 AAA domain RNA_helicase PF00910.17 EGC38598.1 - 0.0085 16.2 0.0 0.028 14.5 0.0 2.0 2 0 0 2 2 1 1 RNA helicase AAA_33 PF13671.1 EGC38598.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.4 1 0 0 1 1 1 0 AAA domain ABC_tran PF00005.22 EGC38598.1 - 0.027 14.7 0.1 0.068 13.4 0.1 1.8 1 1 0 1 1 1 0 ABC transporter AAA_29 PF13555.1 EGC38598.1 - 0.032 13.7 0.0 0.076 12.5 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_11 PF13086.1 EGC38598.1 - 0.036 13.6 0.0 0.064 12.8 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_19 PF13245.1 EGC38598.1 - 0.038 13.7 0.0 0.082 12.6 0.0 1.5 1 0 0 1 1 1 0 Part of AAA domain KaiC PF06745.8 EGC38598.1 - 0.04 13.0 0.0 0.11 11.5 0.0 1.8 1 1 0 1 1 1 0 KaiC AAA_24 PF13479.1 EGC38598.1 - 0.048 13.2 0.2 0.12 11.9 0.1 1.6 1 0 0 1 1 1 0 AAA domain AAA_5 PF07728.9 EGC38598.1 - 0.066 12.9 0.1 0.15 11.7 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_18 PF13238.1 EGC38598.1 - 0.13 12.5 0.1 0.69 10.2 0.0 2.2 2 1 0 2 2 2 0 AAA domain DUF258 PF03193.11 EGC38598.1 - 0.13 11.4 0.0 0.31 10.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function, DUF258 IstB_IS21 PF01695.12 EGC38598.1 - 0.15 11.5 0.0 0.3 10.5 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Pkinase PF00069.20 EGC38599.1 - 1e-48 165.8 0.0 1e-48 165.8 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38599.1 - 3.3e-20 72.2 0.0 1.5e-19 70.1 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase SR-25 PF10500.4 EGC38599.1 - 0.046 13.1 8.3 0.073 12.5 5.7 1.2 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein Med15 PF09606.5 EGC38600.1 - 0.00024 19.4 54.1 0.00027 19.2 37.5 1.2 1 0 0 1 1 1 1 ARC105 or Med15 subunit of Mediator complex non-fungal LAT PF15234.1 EGC38600.1 - 0.096 12.1 4.8 0.18 11.2 3.3 1.4 1 0 0 1 1 1 0 Linker for activation of T-cells Activator_LAG-3 PF11498.3 EGC38600.1 - 4 6.0 67.2 5.1 5.7 46.5 1.1 1 0 0 1 1 1 0 Transcriptional activator LAG-3 ADH_zinc_N PF00107.21 EGC38601.1 - 2.7e-27 94.8 0.0 5.6e-27 93.8 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38601.1 - 5.3e-12 45.4 0.2 9.6e-11 41.4 0.0 2.4 1 1 1 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N_2 PF13602.1 EGC38601.1 - 4.7e-10 40.4 0.0 1.6e-09 38.6 0.0 1.8 2 1 0 2 2 2 1 Zinc-binding dehydrogenase PALP PF00291.20 EGC38601.1 - 0.033 13.4 0.0 0.047 12.9 0.0 1.2 1 0 0 1 1 1 0 Pyridoxal-phosphate dependent enzyme adh_short PF00106.20 EGC38601.1 - 0.044 13.7 0.3 0.07 13.0 0.2 1.3 1 0 0 1 1 1 0 short chain dehydrogenase TrkA_N PF02254.13 EGC38601.1 - 0.084 12.8 0.0 0.16 12.0 0.0 1.5 1 0 0 1 1 1 0 TrkA-N domain SPRY PF00622.23 EGC38602.1 - 1.7e-11 44.2 2.1 7.4e-09 35.7 0.0 2.7 2 0 0 2 2 2 2 SPRY domain PHD PF00628.24 EGC38602.1 - 2.8e-05 23.7 6.9 7.3e-05 22.3 4.8 1.8 1 0 0 1 1 1 1 PHD-finger zf-HC5HC2H_2 PF13832.1 EGC38602.1 - 0.008 16.1 1.5 0.025 14.5 1.0 1.9 1 0 0 1 1 1 1 PHD-zinc-finger like domain C1_1 PF00130.17 EGC38602.1 - 0.15 11.7 7.5 0.041 13.5 2.7 1.9 2 0 0 2 2 2 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-RING_2 PF13639.1 EGC38602.1 - 0.18 11.6 6.0 0.38 10.6 4.1 1.6 1 0 0 1 1 1 0 Ring finger domain PseudoU_synth_2 PF00849.17 EGC38603.1 - 4e-32 111.3 0.8 1e-31 109.9 0.5 1.6 1 1 0 1 1 1 1 RNA pseudouridylate synthase UCH PF00443.24 EGC38604.1 - 4e-56 190.0 18.7 9.8e-56 188.8 13.0 1.7 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC38604.1 - 2e-16 60.2 22.4 1.9e-15 57.0 9.4 3.8 2 2 0 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase zf-UBP PF02148.14 EGC38604.1 - 2.7e-16 59.4 13.1 2.7e-16 59.4 9.1 3.5 3 1 0 3 3 3 1 Zn-finger in ubiquitin-hydrolases and other protein Serinc PF03348.10 EGC38604.1 - 0.0088 14.7 1.5 0.021 13.5 1.0 1.6 1 0 0 1 1 1 1 Serine incorporator (Serinc) PCI PF01399.22 EGC38605.1 - 7.2e-08 32.6 0.1 7.2e-08 32.6 0.1 2.8 2 0 0 2 2 2 1 PCI domain Mitofilin PF09731.4 EGC38605.1 - 0.83 8.2 46.7 2.7 6.5 32.0 1.9 2 0 0 2 2 2 0 Mitochondrial inner membrane protein LRR_4 PF12799.2 EGC38606.1 - 4.5e-31 105.9 69.9 3.5e-08 32.8 7.8 8.5 4 2 5 9 9 8 8 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC38606.1 - 1.4e-28 98.3 38.0 3.6e-10 39.4 4.0 5.6 3 1 2 5 5 5 5 Leucine rich repeat Pkinase_Tyr PF07714.12 EGC38606.1 - 2.1e-23 82.6 0.0 4.3e-23 81.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase LRR_1 PF00560.28 EGC38606.1 - 1.6e-16 57.7 42.3 0.12 12.4 0.1 13.3 11 0 0 11 11 11 5 Leucine Rich Repeat Pkinase PF00069.20 EGC38606.1 - 2.4e-15 56.4 0.0 6.3e-15 55.0 0.0 1.7 1 0 0 1 1 1 1 Protein kinase domain RhoGAP PF00620.22 EGC38606.1 - 3.1e-13 49.5 5.2 3.2e-12 46.2 0.6 2.9 2 0 0 2 2 2 1 RhoGAP domain RGS PF00615.14 EGC38606.1 - 5.7e-12 45.7 1.1 3e-11 43.4 0.8 2.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain Kelch_3 PF13415.1 EGC38606.1 - 8.1e-08 32.2 1.2 0.025 14.7 0.1 4.4 4 0 0 4 4 3 2 Galactose oxidase, central domain LRR_7 PF13504.1 EGC38606.1 - 5.8e-07 28.6 38.8 0.76 10.2 0.3 10.9 9 1 0 9 9 9 4 Leucine rich repeat Kelch_5 PF13854.1 EGC38606.1 - 4e-06 26.6 0.5 0.0021 17.9 0.0 2.8 2 0 0 2 2 2 1 Kelch motif Kelch_4 PF13418.1 EGC38606.1 - 9.4e-06 25.3 1.7 0.094 12.5 0.2 3.1 2 0 0 2 2 2 2 Galactose oxidase, central domain Miro PF08477.8 EGC38606.1 - 7.2e-05 23.2 1.2 0.00016 22.1 0.1 2.3 2 0 0 2 2 1 1 Miro-like protein LRR_6 PF13516.1 EGC38606.1 - 0.00028 20.6 44.9 0.13 12.4 0.0 11.6 9 2 2 11 11 10 2 Leucine Rich repeat Kelch_6 PF13964.1 EGC38606.1 - 0.0014 18.7 6.4 0.093 12.9 0.1 4.2 4 0 0 4 4 3 1 Kelch motif Kelch_1 PF01344.20 EGC38606.1 - 0.002 17.6 0.1 0.59 9.7 0.0 2.9 2 0 0 2 2 2 1 Kelch motif Kelch_2 PF07646.10 EGC38606.1 - 0.0086 15.8 2.0 0.057 13.2 0.1 3.1 2 1 0 2 2 2 1 Kelch motif LRR_9 PF14580.1 EGC38606.1 - 0.16 11.4 15.1 1.8 8.1 1.9 3.5 1 1 2 3 3 3 0 Leucine-rich repeat Zip PF02535.17 EGC38606.1 - 2 7.3 14.3 0.046 12.7 4.7 1.9 2 0 0 2 2 2 0 ZIP Zinc transporter NLPC_P60 PF00877.14 EGC38607.1 - 2.4e-09 36.9 0.5 0.00034 20.3 0.8 2.5 2 0 0 2 2 2 2 NlpC/P60 family Vps8 PF12816.2 EGC38608.1 - 2.7e-48 163.8 3.4 2.7e-48 163.8 2.4 4.1 4 1 0 4 4 4 1 Golgi CORVET complex core vacuolar protein 8 Clathrin PF00637.15 EGC38608.1 - 4.9e-11 42.4 17.1 7.1e-07 28.9 0.7 3.8 3 0 0 3 3 3 3 Region in Clathrin and VPS zf-rbx1 PF12678.2 EGC38608.1 - 7.5e-05 22.7 3.1 0.00021 21.3 2.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC38608.1 - 0.00015 21.4 6.1 0.00038 20.1 4.2 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_2 PF13639.1 EGC38608.1 - 0.0027 17.4 6.2 0.0068 16.2 4.3 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38608.1 - 0.037 13.7 4.6 0.083 12.5 3.2 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38608.1 - 0.061 13.3 3.6 0.23 11.5 2.5 2.0 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38608.1 - 1.4 8.6 7.8 7.3 6.3 5.4 2.3 1 1 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Pirin PF02678.11 EGC38609.1 - 8.1e-38 128.5 0.1 1.3e-37 127.8 0.0 1.4 1 0 0 1 1 1 1 Pirin Pirin_C PF05726.8 EGC38609.1 - 7.8e-33 112.6 0.0 3.4e-31 107.4 0.0 2.1 2 0 0 2 2 2 1 Pirin C-terminal cupin domain KOW PF00467.24 EGC38609.1 - 0.026 14.2 0.3 0.11 12.2 0.0 2.3 2 0 0 2 2 2 0 KOW motif Cupin_2 PF07883.6 EGC38609.1 - 0.038 13.4 0.2 2.3 7.8 0.1 2.3 2 0 0 2 2 2 0 Cupin domain FNIP PF05725.7 EGC38610.1 - 4.6e-92 301.7 43.1 2.2e-15 56.3 1.2 7.8 3 2 2 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 EGC38610.1 - 4.8e-05 23.2 28.2 0.25 11.3 0.1 9.1 2 2 9 11 11 11 3 Protein of unknown function (DUF1769) MerC PF03203.9 EGC38610.1 - 0.0061 16.9 0.0 29 5.0 0.0 3.7 1 1 1 4 4 4 1 MerC mercury resistance protein Phage_min_tail PF05939.8 EGC38610.1 - 0.15 12.0 0.0 21 5.1 0.0 4.0 4 1 1 5 5 5 0 Phage minor tail protein THUMP PF02926.12 EGC38612.1 - 8.6e-11 41.8 1.1 8.6e-11 41.8 0.8 1.9 2 0 0 2 2 2 1 THUMP domain DNA_pol3_alpha PF07733.7 EGC38612.1 - 0.0031 16.0 0.7 0.0045 15.4 0.0 1.5 2 0 0 2 2 2 1 Bacterial DNA polymerase III alpha subunit DUF310 PF03750.8 EGC38612.1 - 0.065 13.4 1.1 7 6.8 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF310) FNIP PF05725.7 EGC38613.1 - 2e-160 520.5 52.0 3.3e-15 55.7 1.4 13.1 7 1 4 14 14 14 14 FNIP Repeat zf-C2HC_2 PF13913.1 EGC38613.1 - 0.1 12.3 1.7 61 3.4 0.0 5.0 5 0 0 5 5 5 0 zinc-finger of a C2HC-type DUF1769 PF08588.5 EGC38613.1 - 0.28 11.1 34.3 15 5.6 0.1 12.3 6 5 11 17 17 17 0 Protein of unknown function (DUF1769) ketoacyl-synt PF00109.21 EGC38614.1 - 1.9e-60 204.4 0.0 4.3e-60 203.3 0.0 1.6 2 0 0 2 2 2 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38614.1 - 7.8e-45 153.5 0.0 1.3e-44 152.8 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC38614.1 - 1e-44 152.3 0.0 2.3e-44 151.1 0.0 1.6 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC38614.1 - 6.2e-32 109.9 0.0 2.1e-31 108.2 0.0 2.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38614.1 - 3.1e-26 92.1 0.0 1.9e-24 86.2 0.0 2.5 2 0 0 2 2 2 1 KR domain PS-DH PF14765.1 EGC38614.1 - 8.6e-23 80.9 0.0 1.3e-22 80.2 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_12 PF08242.7 EGC38614.1 - 4.1e-21 75.3 2.8 1.1e-20 73.9 0.0 3.5 3 0 0 3 3 1 1 Methyltransferase domain adh_short PF00106.20 EGC38614.1 - 1.6e-20 73.7 0.0 3.1e-17 62.9 0.0 2.8 3 0 0 3 3 3 2 short chain dehydrogenase Epimerase PF01370.16 EGC38614.1 - 5.8e-13 48.8 0.1 1.4e-07 31.2 0.0 2.7 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family ADH_zinc_N_2 PF13602.1 EGC38614.1 - 9.6e-08 32.9 0.0 2.3e-07 31.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGC38614.1 - 8.6e-06 25.9 0.1 0.00014 22.0 0.2 2.6 2 0 0 2 2 2 1 Phosphopantetheine attachment site ADH_N PF08240.7 EGC38614.1 - 1.6e-05 24.5 0.1 3.6e-05 23.4 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38614.1 - 2.5e-05 24.6 0.0 0.00013 22.3 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38614.1 - 8.6e-05 22.3 0.0 0.00028 20.6 0.0 1.9 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38614.1 - 0.00075 20.0 0.0 0.0029 18.1 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC38614.1 - 0.0018 17.2 0.0 0.0044 16.0 0.0 1.6 1 0 0 1 1 1 1 Thiolase, N-terminal domain Senescence PF06911.7 EGC38615.1 - 4.4e-19 68.8 6.2 7.7e-19 68.0 4.3 1.4 1 0 0 1 1 1 1 Senescence-associated protein PH PF00169.24 EGC38615.1 - 8.4e-07 29.1 0.0 3.6e-06 27.1 0.0 2.1 1 0 0 1 1 1 1 PH domain Pkinase PF00069.20 EGC38617.1 - 3.3e-73 246.0 0.0 4.3e-73 245.6 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38617.1 - 3.1e-35 121.5 0.1 6.6e-35 120.4 0.1 1.6 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC38617.1 - 5.7e-06 25.5 0.0 1.7e-05 23.9 0.0 1.7 1 1 1 2 2 2 1 Kinase-like Kdo PF06293.9 EGC38617.1 - 0.03 13.4 0.5 0.052 12.6 0.3 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC38617.1 - 0.14 11.8 0.1 0.69 9.6 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family DUF1754 PF08555.5 EGC38618.1 - 4e-07 30.5 27.4 1.5e-06 28.7 15.7 2.7 1 1 1 2 2 2 1 Eukaryotic family of unknown function (DUF1754) PP2C_C PF07830.8 EGC38618.1 - 0.012 15.6 1.4 0.014 15.4 0.2 1.6 1 1 1 2 2 2 0 Protein serine/threonine phosphatase 2C, C-terminal domain Med28 PF11594.3 EGC38618.1 - 0.11 12.7 4.6 0.16 12.2 3.2 1.3 1 0 0 1 1 1 0 Mediator complex subunit 28 NST1 PF13945.1 EGC38618.1 - 0.11 12.5 12.5 0.13 12.2 8.7 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator SRP-alpha_N PF04086.8 EGC38618.1 - 0.4 10.0 14.4 0.45 9.8 10.0 1.1 1 0 0 1 1 1 0 Signal recognition particle, alpha subunit, N-terminal DUF2058 PF09831.4 EGC38618.1 - 0.79 9.5 13.7 1 9.2 9.5 1.1 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2058) Hydrolase_3 PF08282.7 EGC38618.1 - 0.85 9.1 6.5 0.98 8.9 4.5 1.1 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase PRP1_N PF06424.7 EGC38618.1 - 1.6 9.0 9.8 2.1 8.6 6.8 1.1 1 0 0 1 1 1 0 PRP1 splicing factor, N-terminal PMSI1 PF15322.1 EGC38618.1 - 1.8 7.5 6.6 2.1 7.3 4.6 1.0 1 0 0 1 1 1 0 Protein missing in infertile sperm 1, putative GCP5-Mod21 PF14609.1 EGC38618.1 - 1.9 6.4 9.1 2.2 6.3 6.3 1.0 1 0 0 1 1 1 0 gamma-Tubulin ring complex non-core subunit mod21 DDHD PF02862.12 EGC38618.1 - 2.3 7.9 9.1 2.6 7.7 6.3 1.0 1 0 0 1 1 1 0 DDHD domain HSP70 PF00012.15 EGC38618.1 - 2.7 5.7 11.3 3.1 5.5 7.8 1.0 1 0 0 1 1 1 0 Hsp70 protein DUF4094 PF13334.1 EGC38618.1 - 3.1 8.2 9.6 1.3 9.4 1.3 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4094) Med23 PF11573.3 EGC38618.1 - 3.3 4.9 6.4 3.9 4.6 4.4 1.0 1 0 0 1 1 1 0 Mediator complex subunit 23 Pex16 PF08610.5 EGC38618.1 - 4.6 6.1 6.5 5.2 5.9 4.5 1.0 1 0 0 1 1 1 0 Peroxisomal membrane protein (Pex16) CDC45 PF02724.9 EGC38618.1 - 5.7 4.8 11.0 6.4 4.6 7.6 1.0 1 0 0 1 1 1 0 CDC45-like protein UvrD-helicase PF00580.16 EGC38618.1 - 6.6 5.9 9.9 7.3 5.7 6.9 1.0 1 0 0 1 1 1 0 UvrD/REP helicase N-terminal domain Ycf1 PF05758.7 EGC38618.1 - 7.5 4.1 13.1 8.3 3.9 9.1 1.0 1 0 0 1 1 1 0 Ycf1 Spc97_Spc98 PF04130.8 EGC38619.1 - 1.5e-131 439.3 20.4 1.5e-131 439.3 14.1 2.3 3 0 0 3 3 3 1 Spc97 / Spc98 family Nucleoplasmin PF03066.10 EGC38619.1 - 0.0041 16.6 2.9 0.0085 15.6 2.0 1.5 1 0 0 1 1 1 1 Nucleoplasmin MutS_V PF00488.16 EGC38620.1 - 9.8e-72 241.1 0.0 2e-71 240.1 0.0 1.6 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC38620.1 - 3.2e-26 92.3 0.2 6.7e-26 91.3 0.1 1.6 1 0 0 1 1 1 1 MutS domain III MutS_IV PF05190.13 EGC38620.1 - 0.0004 20.4 0.2 0.0004 20.4 0.1 2.9 3 0 0 3 3 3 1 MutS family domain IV Actin PF00022.14 EGC38622.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC38622.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) WD40 PF00400.27 EGC38623.1 - 5.6e-29 98.9 10.0 8.2e-07 28.6 0.0 6.2 6 0 0 6 6 6 5 WD domain, G-beta repeat eIF2A PF08662.6 EGC38623.1 - 0.002 17.8 0.8 0.034 13.8 0.1 2.5 2 1 1 3 3 3 1 Eukaryotic translation initiation factor eIF2A Fungal_lectin PF07938.7 EGC38623.1 - 0.02 14.2 2.0 1.3 8.2 0.0 2.6 2 1 1 3 3 3 0 Fungal fucose-specific lectin Nup160 PF11715.3 EGC38623.1 - 0.082 11.0 1.4 0.21 9.6 0.2 2.0 1 1 1 2 2 2 0 Nucleoporin Nup120/160 ubiquitin PF00240.18 EGC38624.1 - 3.1e-16 58.5 0.0 6.4e-16 57.5 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC38624.1 - 5.2e-07 29.2 0.1 1.7e-06 27.6 0.1 2.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC38624.1 - 0.032 14.4 1.9 0.16 12.1 0.0 3.0 3 1 0 3 3 3 0 DUF2407 ubiquitin-like domain PPTA PF01239.17 EGC38625.1 - 8.7e-46 151.4 14.0 5.6e-10 38.1 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PH_11 PF15413.1 EGC38625.1 - 0.62 10.3 0.1 0.62 10.3 0.1 3.5 2 1 2 4 4 4 0 Pleckstrin homology domain PPTA PF01239.17 EGC38626.1 - 8.7e-46 151.4 14.0 5.6e-10 38.1 0.1 5.4 5 0 0 5 5 5 5 Protein prenyltransferase alpha subunit repeat PH_11 PF15413.1 EGC38626.1 - 0.62 10.3 0.1 0.62 10.3 0.1 3.5 2 1 2 4 4 4 0 Pleckstrin homology domain SIR2 PF02146.12 EGC38627.1 - 5e-59 199.0 0.0 9.1e-59 198.1 0.0 1.5 1 0 0 1 1 1 1 Sir2 family zf-UBP PF02148.14 EGC38627.1 - 3.4e-18 65.4 12.9 3.4e-18 65.4 9.0 1.7 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein Mucin PF01456.12 EGC38627.1 - 1.1e-05 25.2 11.6 1.1e-05 25.2 8.0 1.7 2 0 0 2 2 2 1 Mucin-like glycoprotein TPP_enzyme_M PF00205.17 EGC38627.1 - 0.00055 19.6 0.0 0.0024 17.6 0.0 1.9 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, central domain zf-C3HC4_3 PF13920.1 EGC38627.1 - 0.2 11.3 11.6 0.21 11.2 2.2 3.5 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Dicty_REP PF05086.7 EGC38627.1 - 0.27 8.9 12.7 0.36 8.5 8.8 1.1 1 0 0 1 1 1 0 Dictyostelium (Slime Mold) REP protein SSP160 PF06933.6 EGC38627.1 - 0.55 8.1 22.0 0.85 7.5 15.2 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 GET2 PF08690.5 EGC38627.1 - 0.83 8.8 8.9 1.2 8.2 6.2 1.1 1 0 0 1 1 1 0 GET complex subunit GET2 PP2C PF00481.16 EGC38628.1 - 9.5e-61 205.3 0.0 9.5e-61 205.3 0.0 3.3 3 1 1 4 4 4 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGC38628.1 - 0.0079 15.6 2.6 0.015 14.7 0.1 2.7 2 1 0 2 2 2 1 Protein phosphatase 2C Sulf_transp PF04143.9 EGC38629.1 - 1.7e-10 40.7 18.5 7.1e-07 29.1 5.4 3.7 4 1 0 4 4 4 2 Sulphur transport Polysacc_synt_C PF14667.1 EGC38629.1 - 0.0035 17.1 1.6 0.0035 17.1 1.1 3.2 3 1 1 4 4 4 1 Polysaccharide biosynthesis C-terminal domain Phage_holin_2 PF04550.7 EGC38629.1 - 0.21 11.7 3.3 0.19 11.8 0.2 2.4 2 0 0 2 2 2 0 Phage holin family 2 LRR_4 PF12799.2 EGC38630.1 - 0.012 15.1 6.9 0.72 9.5 0.3 4.0 3 0 0 3 3 3 0 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC38630.1 - 0.081 13.0 19.0 1 9.6 0.1 7.3 6 2 1 7 7 7 0 Leucine Rich Repeat Laminin_EGF PF00053.19 EGC38630.1 - 0.37 10.7 9.7 0.94 9.4 6.7 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_2 PF07974.8 EGC38630.1 - 0.66 10.1 10.7 1.6 8.9 7.4 1.7 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.7 EGC38631.1 - 2.4e-61 203.4 88.1 1.3e-05 25.0 0.5 17.6 3 2 17 23 23 23 23 FNIP Repeat Thaumatin PF00314.12 EGC38631.1 - 0.0018 17.8 0.3 21 4.4 0.0 5.9 5 2 2 7 7 7 1 Thaumatin family DUF1563 PF07599.6 EGC38631.1 - 0.039 13.8 1.9 1.3e+02 2.5 0.0 4.9 4 0 0 4 4 4 0 Protein of unknown function (DUF1563) Ribosomal_TL5_C PF14693.1 EGC38631.1 - 0.42 10.8 6.5 1.4e+02 2.7 0.0 6.4 9 0 0 9 9 9 0 Ribosomal protein TL5, C-terminal domain Methyltransf_11 PF08241.7 EGC38633.1 - 4.7e-20 71.8 0.1 8.5e-20 71.0 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38633.1 - 1.2e-13 50.8 0.5 1.9e-13 50.2 0.3 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC38633.1 - 1.3e-13 51.2 0.1 2.4e-13 50.3 0.1 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38633.1 - 7.1e-12 45.9 0.1 1.5e-11 44.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC38633.1 - 4.4e-11 43.1 0.1 8.8e-11 42.1 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC38633.1 - 2e-09 37.3 0.0 2.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC38633.1 - 6.5e-08 31.9 0.0 9.9e-08 31.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGC38633.1 - 1.2e-05 25.2 0.0 2.9e-05 24.0 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC38633.1 - 1.3e-05 24.4 0.2 2.3e-05 23.6 0.1 1.5 1 1 0 1 1 1 1 Mycolic acid cyclopropane synthetase RrnaAD PF00398.15 EGC38633.1 - 0.00017 20.7 0.0 0.00026 20.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_9 PF08003.6 EGC38633.1 - 0.00021 20.0 0.0 0.00051 18.8 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1698) Methyltransf_4 PF02390.12 EGC38633.1 - 0.00033 19.7 0.0 0.00096 18.2 0.0 1.8 1 1 0 1 1 1 1 Putative methyltransferase Methyltransf_8 PF05148.10 EGC38633.1 - 0.0013 18.3 0.4 0.0064 16.1 0.2 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase MTS PF05175.9 EGC38633.1 - 0.0024 17.2 0.0 0.0063 15.9 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase small domain MetW PF07021.7 EGC38633.1 - 0.0026 17.1 0.1 0.0038 16.6 0.0 1.2 1 0 0 1 1 1 1 Methionine biosynthesis protein MetW Synaptobrevin PF00957.16 EGC38633.1 - 0.017 14.6 0.0 0.031 13.8 0.0 1.4 1 0 0 1 1 1 0 Synaptobrevin Methyltransf_15 PF09445.5 EGC38633.1 - 0.021 14.3 0.5 0.074 12.5 0.1 1.9 1 1 0 2 2 2 0 RNA cap guanine-N2 methyltransferase Methyltransf_PK PF05891.7 EGC38633.1 - 0.047 12.9 0.1 0.096 11.9 0.1 1.5 1 1 0 1 1 1 0 AdoMet dependent proline di-methyltransferase NodS PF05401.6 EGC38633.1 - 0.094 12.1 0.0 0.14 11.5 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Tetraspannin PF00335.15 EGC38634.1 - 4.5e-27 94.7 11.7 5.4e-27 94.5 8.1 1.0 1 0 0 1 1 1 1 Tetraspanin family DUF2976 PF11190.3 EGC38634.1 - 0.0019 17.6 1.3 0.0019 17.6 0.9 2.9 3 0 0 3 3 3 1 Protein of unknown function (DUF2976) DUF1206 PF06724.6 EGC38634.1 - 0.0073 16.0 1.6 0.0073 16.0 1.1 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1206) FA_desaturase PF00487.19 EGC38634.1 - 0.026 13.9 0.2 0.045 13.1 0.1 1.4 1 0 0 1 1 1 0 Fatty acid desaturase IncA PF04156.9 EGC38634.1 - 0.09 12.3 0.1 0.09 12.3 0.1 3.6 3 1 1 4 4 3 0 IncA protein DUF4064 PF13273.1 EGC38634.1 - 0.15 12.1 15.3 7.2 6.7 9.2 2.6 2 1 1 3 3 3 0 Protein of unknown function (DUF4064) DUF373 PF04123.8 EGC38634.1 - 0.23 10.4 6.7 0.064 12.2 2.5 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF373) DUF1628 PF07790.6 EGC38634.1 - 1.5 9.6 4.3 4.8 8.0 0.2 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF1628) DUF3169 PF11368.3 EGC38634.1 - 1.8 7.7 10.2 0.11 11.6 1.8 2.4 2 1 0 2 2 2 0 Protein of unknown function (DUF3169) DUF3784 PF12650.2 EGC38634.1 - 2.1 8.3 13.9 1.5 8.8 6.7 2.1 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) DUF1469 PF07332.6 EGC38634.1 - 8.5 6.1 14.8 0.44 10.2 2.2 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1469) CRAL_TRIO PF00650.15 EGC38635.1 - 4.1e-15 55.6 0.0 8e-15 54.6 0.0 1.5 1 0 0 1 1 1 1 CRAL/TRIO domain CRAL_TRIO_N PF03765.10 EGC38635.1 - 6.3e-11 42.2 0.6 6.3e-11 42.2 0.4 2.7 2 1 0 2 2 2 1 CRAL/TRIO, N-terminal domain GAGA_bind PF06217.7 EGC38635.1 - 0.21 11.5 14.3 0.29 11.0 9.9 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family RNA_polI_A34 PF08208.6 EGC38635.1 - 0.32 10.6 37.1 0.51 9.9 25.7 1.2 1 0 0 1 1 1 0 DNA-directed RNA polymerase I subunit RPA34.5 RNase_H2-Ydr279 PF09468.5 EGC38635.1 - 0.62 9.2 19.5 1.2 8.2 13.5 1.5 1 0 0 1 1 1 0 Ydr279p protein family (RNase H2 complex component) AAA_11 PF13086.1 EGC38635.1 - 1.5 8.3 8.0 2.9 7.3 5.6 1.4 1 0 0 1 1 1 0 AAA domain CAF-1_p150 PF11600.3 EGC38635.1 - 3.4 6.9 48.7 5.7 6.2 33.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal NARP1 PF12569.3 EGC38635.1 - 3.8 6.1 28.5 5.5 5.6 19.8 1.2 1 0 0 1 1 1 0 NMDA receptor-regulated protein 1 ORC2 PF04084.9 EGC38636.1 - 7.2e-77 258.3 3.4 8.8e-77 258.1 2.3 1.0 1 0 0 1 1 1 1 Origin recognition complex subunit 2 DUF241 PF03087.9 EGC38636.1 - 0.092 12.2 3.7 1.1 8.7 0.2 2.1 2 0 0 2 2 2 0 Arabidopsis protein of unknown function BTV_NS2 PF04514.7 EGC38636.1 - 0.93 8.3 3.9 1.2 7.9 2.7 1.1 1 0 0 1 1 1 0 Bluetongue virus non-structural protein NS2 Asparaginase_2 PF01112.13 EGC38637.1 - 1.2e-102 342.9 9.2 1.5e-102 342.6 6.4 1.0 1 0 0 1 1 1 1 Asparaginase zf-RING_2 PF13639.1 EGC38639.1 - 1.5e-13 50.3 11.9 3.3e-13 49.2 6.8 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38639.1 - 5.2e-08 32.4 6.0 1e-07 31.5 4.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC38639.1 - 2.1e-07 30.9 13.1 2e-06 27.8 8.3 2.7 2 1 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC38639.1 - 3.5e-07 29.7 9.7 1.1e-06 28.1 6.7 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38639.1 - 5.2e-07 29.5 9.4 5.2e-07 29.5 6.5 1.9 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38639.1 - 3.1e-05 23.5 6.5 3.1e-05 23.5 4.5 2.2 2 0 0 2 2 2 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC38639.1 - 0.00061 19.4 7.9 0.00061 19.4 5.4 2.3 2 0 0 2 2 2 1 RING-type zinc-finger CUE PF02845.11 EGC38639.1 - 0.0044 16.4 0.1 0.0044 16.4 0.1 2.2 2 0 0 2 2 2 1 CUE domain zf-C3HC4_4 PF15227.1 EGC38639.1 - 0.0056 16.5 5.5 0.012 15.4 3.8 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC38639.1 - 0.03 14.1 11.8 0.18 11.6 6.4 2.8 2 1 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger Rad50_zn_hook PF04423.9 EGC38639.1 - 0.037 13.4 0.4 0.089 12.2 0.0 1.8 2 0 0 2 2 1 0 Rad50 zinc hook motif FANCL_C PF11793.3 EGC38639.1 - 0.15 12.0 3.9 0.49 10.3 2.7 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain Prok-RING_4 PF14447.1 EGC38639.1 - 0.99 9.0 5.6 1.2 8.7 2.7 2.1 2 0 0 2 2 2 0 Prokaryotic RING finger family 4 RINGv PF12906.2 EGC38639.1 - 1.8 8.6 9.8 4 7.5 6.8 1.6 1 0 0 1 1 1 0 RING-variant domain zf-RING_4 PF14570.1 EGC38639.1 - 3 7.5 6.8 4.2 7.0 3.8 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain Pkinase PF00069.20 EGC38640.1 - 1.2e-73 247.4 0.1 1.8e-73 246.8 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38640.1 - 6.7e-46 156.4 0.0 9.1e-46 156.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC38640.1 - 1.4e-07 30.7 0.0 3e-07 29.6 0.0 1.5 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGC38640.1 - 0.01 15.2 0.0 0.33 10.2 0.0 2.6 3 0 0 3 3 3 1 RIO1 family YrbL-PhoP_reg PF10707.4 EGC38640.1 - 0.013 14.7 0.1 0.031 13.6 0.0 1.6 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL Menin PF05053.8 EGC38640.1 - 0.28 9.3 1.4 0.34 9.0 1.0 1.1 1 0 0 1 1 1 0 Menin GSH-S_ATP PF02955.11 EGC38641.1 - 1.2e-05 24.5 0.1 2e-05 23.8 0.1 1.3 1 0 0 1 1 1 1 Prokaryotic glutathione synthetase, ATP-grasp domain CBFD_NFYB_HMF PF00808.18 EGC38642.1 - 5.4e-28 96.8 1.5 6.3e-28 96.6 1.1 1.1 1 0 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Histone PF00125.19 EGC38642.1 - 5.7e-05 23.1 0.1 7.2e-05 22.8 0.0 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 Bromo_TP PF07524.8 EGC38642.1 - 0.0011 18.6 0.0 0.0016 18.1 0.0 1.2 1 0 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EGC38642.1 - 0.014 15.2 0.1 0.018 14.8 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit PIGA PF08288.7 EGC38643.1 - 9.4e-45 150.9 1.9 1.3e-44 150.4 0.5 1.9 2 0 0 2 2 2 1 PIGA (GPI anchor biosynthesis) Glycos_transf_1 PF00534.15 EGC38643.1 - 2.3e-29 101.9 0.0 5.1e-29 100.8 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_4 PF13439.1 EGC38643.1 - 2.5e-16 59.9 0.2 4e-16 59.2 0.1 1.3 1 0 0 1 1 1 1 Glycosyltransferase Family 4 Glyco_trans_1_4 PF13692.1 EGC38643.1 - 1.2e-11 44.9 0.0 2.3e-11 43.9 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGC38643.1 - 1.8e-10 41.2 0.0 2.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_4_2 PF13477.1 EGC38643.1 - 3.1e-06 27.0 0.5 5.9e-06 26.1 0.3 1.4 1 0 0 1 1 1 1 Glycosyl transferase 4-like Glyco_trans_1_2 PF13524.1 EGC38643.1 - 0.0089 16.2 0.0 0.034 14.4 0.0 2.1 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGC38643.1 - 0.085 12.3 0.1 0.24 10.8 0.1 1.8 1 1 0 1 1 1 0 Starch synthase catalytic domain Ndc80_HEC PF03801.8 EGC38644.1 - 2e-25 89.0 0.1 2e-25 89.0 0.1 4.0 3 1 0 3 3 3 2 HEC/Ndc80p family DUF1664 PF07889.7 EGC38644.1 - 2.1 8.1 38.0 1.3 8.8 6.2 4.5 3 1 2 5 5 5 0 Protein of unknown function (DUF1664) FNIP PF05725.7 EGC38647.1 - 8.8e-44 147.2 20.6 3.5e-13 49.2 0.5 6.1 3 2 2 6 6 6 6 FNIP Repeat zf-C2H2_jaz PF12171.3 EGC38647.1 - 4.4e-06 26.6 4.5 0.029 14.4 0.7 2.4 2 0 0 2 2 2 2 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC38647.1 - 2.8e-05 24.1 5.0 0.0042 17.2 0.2 2.4 2 0 0 2 2 2 2 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGC38647.1 - 5e-05 23.3 5.8 0.0083 16.2 1.4 2.4 1 1 1 2 2 2 2 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGC38647.1 - 0.12 12.8 2.5 9 6.8 0.1 3.0 2 0 0 2 2 2 0 C2H2-type zinc finger Bacillus_HBL PF05791.6 EGC38648.1 - 0.024 14.0 19.2 4.6 6.5 13.2 2.4 1 1 0 1 1 1 0 Bacillus haemolytic enterotoxin (HBL) V_ATPase_I PF01496.14 EGC38648.1 - 0.027 12.3 16.3 0.037 11.8 11.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family AAA_27 PF13514.1 EGC38648.1 - 0.043 11.5 11.4 0.26 8.9 0.6 2.3 1 1 1 2 2 2 0 AAA domain CENP-F_leu_zip PF10473.4 EGC38648.1 - 0.082 12.7 20.8 0.064 13.1 3.9 2.6 1 1 1 2 2 2 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Myosin_tail_1 PF01576.14 EGC38648.1 - 0.084 10.5 21.1 0.11 10.2 3.4 2.1 1 1 0 1 1 1 0 Myosin tail CH PF00307.26 EGC38648.1 - 0.22 11.5 3.9 0.26 11.3 0.1 2.3 2 1 0 2 2 2 0 Calponin homology (CH) domain Reo_sigmaC PF04582.7 EGC38648.1 - 0.25 10.4 3.1 0.8 8.8 0.2 2.0 1 1 1 2 2 2 0 Reovirus sigma C capsid protein Baculo_PEP_C PF04513.7 EGC38648.1 - 0.31 10.8 11.7 9.6 6.0 5.8 2.9 1 1 1 2 2 2 0 Baculovirus polyhedron envelope protein, PEP, C terminus HOOK PF05622.7 EGC38648.1 - 0.33 8.7 22.3 3.4 5.3 15.4 2.0 1 1 0 1 1 1 0 HOOK protein APG6 PF04111.7 EGC38648.1 - 0.35 9.8 18.3 0.45 9.5 5.4 2.1 2 0 0 2 2 2 0 Autophagy protein Apg6 IncA PF04156.9 EGC38648.1 - 0.67 9.5 21.6 1.7 8.1 8.8 2.8 1 1 1 2 2 2 0 IncA protein DUF3508 PF12018.3 EGC38648.1 - 0.85 8.5 10.2 0.99 8.3 6.5 1.7 1 1 0 1 1 1 0 Domain of unknown function (DUF3508) ALMT PF11744.3 EGC38648.1 - 1.8 7.1 7.3 3.1 6.3 5.0 1.6 1 1 0 1 1 1 0 Aluminium activated malate transporter zf-C4H2 PF10146.4 EGC38648.1 - 1.8 8.5 18.7 0.9 9.5 6.9 2.5 2 1 0 2 2 2 0 Zinc finger-containing protein DUF4140 PF13600.1 EGC38648.1 - 6 7.3 8.2 1.6 9.1 0.7 2.9 2 2 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) DUF4200 PF13863.1 EGC38648.1 - 6.4 6.7 26.5 0.93 9.4 7.9 3.6 2 2 1 3 3 3 0 Domain of unknown function (DUF4200) Telomere_reg-2 PF10193.4 EGC38648.1 - 6.9 6.9 8.1 4 7.7 1.4 3.1 2 1 2 4 4 4 0 Telomere length regulation protein ThiF PF00899.16 EGC38649.1 - 1e-38 132.2 0.5 7e-38 129.5 0.2 2.1 2 0 0 2 2 2 1 ThiF family UBACT PF02134.16 EGC38649.1 - 1.2e-27 95.2 0.9 2.8e-27 94.0 0.6 1.7 1 0 0 1 1 1 1 Repeat in ubiquitin-activating (UBA) protein E2_bind PF08825.5 EGC38649.1 - 4.2e-20 71.2 0.0 6.8e-20 70.6 0.0 1.3 1 0 0 1 1 1 1 E2 binding domain UBA_e1_thiolCys PF10585.4 EGC38649.1 - 5.1e-13 48.1 0.8 1.1e-12 47.1 0.5 1.5 1 0 0 1 1 1 1 Ubiquitin-activating enzyme active site UAE_UbL PF14732.1 EGC38649.1 - 0.00011 22.2 0.0 0.00026 21.0 0.0 1.6 1 0 0 1 1 1 1 Ubiquitin/SUMO-activating enzyme ubiquitin-like domain Shikimate_DH PF01488.15 EGC38649.1 - 0.00034 20.7 0.0 0.00066 19.7 0.0 1.4 1 0 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase NAD_binding_4 PF07993.7 EGC38650.1 - 1.6e-32 112.3 0.0 2.9e-32 111.5 0.0 1.3 1 0 0 1 1 1 1 Male sterility protein Acyl_transf_1 PF00698.16 EGC38650.1 - 4.2e-28 98.6 0.0 6.6e-28 97.9 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Epimerase PF01370.16 EGC38650.1 - 6.1e-10 38.9 0.0 1.6e-09 37.5 0.0 1.7 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family zf-RING_2 PF13639.1 EGC38651.1 - 9.5e-11 41.3 10.8 1.7e-10 40.5 7.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC38651.1 - 5e-08 32.4 9.7 7.8e-08 31.8 6.7 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC38651.1 - 9.2e-07 28.8 7.5 2.3e-06 27.6 5.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC38651.1 - 2e-06 27.3 15.9 4.2e-06 26.2 11.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38651.1 - 4.9e-06 26.4 15.1 8.3e-06 25.7 10.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC38651.1 - 0.00011 21.8 13.9 0.00019 21.0 9.6 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC38651.1 - 0.0019 18.0 13.8 0.004 16.9 9.6 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC38651.1 - 0.0076 16.0 4.7 0.017 14.9 3.2 1.6 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger DUF4199 PF13858.1 EGC38651.1 - 0.018 14.9 0.2 0.018 14.9 0.2 2.8 2 2 0 2 2 1 0 Protein of unknown function (DUF4199) zf-RING_6 PF14835.1 EGC38651.1 - 0.051 13.3 5.1 0.11 12.2 3.5 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_4 PF14570.1 EGC38651.1 - 0.091 12.3 14.9 0.2 11.2 10.4 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC38651.1 - 0.12 12.1 7.7 0.39 10.4 5.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger DUF1183 PF06682.7 EGC38651.1 - 0.27 10.8 5.3 0.53 9.8 3.7 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1183) TFIIA PF03153.8 EGC38651.1 - 0.41 10.4 40.3 0.88 9.3 27.9 1.4 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Zip PF02535.17 EGC38651.1 - 1 8.3 5.7 3.8 6.4 0.1 2.2 2 0 0 2 2 2 0 ZIP Zinc transporter DUF1789 PF08748.6 EGC38651.1 - 5.9 7.0 16.5 3.9 7.5 9.2 2.4 2 1 0 2 2 2 0 Domain of unknown function (DUF1789) Methyltransf_11 PF08241.7 EGC38652.1 - 1e-09 38.7 0.0 1.8e-09 37.9 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC38652.1 - 0.00035 19.7 0.0 0.00045 19.3 0.0 1.3 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGC38652.1 - 0.0017 18.0 0.0 0.0024 17.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC38652.1 - 0.0032 17.8 0.0 0.0074 16.6 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Xol-1_GHMP-like PF09109.5 EGC38652.1 - 0.027 14.5 0.0 0.046 13.8 0.0 1.4 1 0 0 1 1 1 0 Switch protein XOL-1, GHMP-like DUF1895 PF08988.5 EGC38652.1 - 0.077 13.0 0.0 4.9 7.2 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1895) Tim44 PF04280.10 EGC38653.1 - 0.0026 17.7 0.0 0.0081 16.1 0.0 1.8 1 0 0 1 1 1 1 Tim44-like domain DinB PF05163.7 EGC38653.1 - 0.012 15.3 1.0 0.03 14.0 0.7 1.6 1 0 0 1 1 1 0 DinB family 7tm_1 PF00001.16 EGC38654.1 - 1.2e-06 27.8 21.5 0.051 12.7 0.9 3.6 2 1 1 3 3 3 2 7 transmembrane receptor (rhodopsin family) Git3_C PF11970.3 EGC38654.1 - 0.18 11.6 7.9 1.1 9.1 0.4 3.2 3 0 0 3 3 3 0 G protein-coupled glucose receptor regulating Gpa2 C-term Nucleic_acid_bd PF13820.1 EGC38655.1 - 0.0017 17.9 1.0 0.74 9.4 0.5 2.8 2 0 0 2 2 2 2 Putative nucleic acid-binding region DUF3439 PF11921.3 EGC38655.1 - 0.74 9.5 14.4 1.7 8.4 10.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) SH3_1 PF00018.23 EGC38656.1 - 2.3e-14 52.4 0.3 5.4e-14 51.3 0.2 1.7 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC38656.1 - 6.9e-13 47.9 0.2 1.3e-12 47.1 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC38656.1 - 2.2e-10 39.8 0.0 3.7e-10 39.1 0.0 1.3 1 0 0 1 1 1 1 Variant SH3 domain Peptidase_C33 PF05412.7 EGC38656.1 - 0.13 12.0 0.6 0.22 11.3 0.4 1.3 1 0 0 1 1 1 0 Equine arterivirus Nsp2-type cysteine proteinase HR1 PF02185.11 EGC38657.1 - 0.0053 16.4 4.1 0.012 15.3 2.8 1.6 1 0 0 1 1 1 1 Hr1 repeat Rab5-bind PF09311.6 EGC38657.1 - 0.01 15.7 1.3 0.018 14.9 0.9 1.4 1 0 0 1 1 1 0 Rabaptin-like protein GAT PF03127.9 EGC38657.1 - 0.01 15.7 0.7 6.8 6.7 0.0 2.5 2 1 0 2 2 2 0 GAT domain Transposase_22 PF02994.9 EGC38657.1 - 0.033 12.6 1.5 0.057 11.9 1.1 1.3 1 0 0 1 1 1 0 L1 transposable element DUF4618 PF15397.1 EGC38657.1 - 3.4 6.9 10.2 0.022 14.1 1.2 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF4618) Clat_adaptor_s PF01217.15 EGC38658.1 - 8.7e-48 161.6 5.2 1e-47 161.4 3.6 1.0 1 0 0 1 1 1 1 Clathrin adaptor complex small chain Pkinase PF00069.20 EGC38659.1 - 5.3e-64 215.8 0.1 5.3e-64 215.8 0.1 1.7 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38659.1 - 5.3e-40 137.1 0.0 8e-40 136.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC38659.1 - 4.9e-10 38.8 0.0 1e-09 37.7 0.0 1.6 2 0 0 2 2 2 1 Kinase-like RIO1 PF01163.17 EGC38659.1 - 0.0013 18.1 0.4 0.0037 16.6 0.3 1.8 1 0 0 1 1 1 1 RIO1 family APH PF01636.18 EGC38659.1 - 0.2 11.3 0.0 2.1 7.9 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family Glyco_transf_22 PF03901.12 EGC38660.1 - 8.5e-82 275.3 39.4 1.1e-81 274.9 27.3 1.1 1 0 0 1 1 1 1 Alg9-like mannosyltransferase family DUF1697 PF08002.6 EGC38661.1 - 7.5e-11 42.2 0.0 9.8e-11 41.8 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Vps35 PF03635.12 EGC38661.1 - 0.02 13.0 0.1 0.02 13.0 0.0 1.1 1 0 0 1 1 1 0 Vacuolar protein sorting-associated protein 35 p450 PF00067.17 EGC38662.1 - 4.5e-56 190.3 0.4 2.1e-55 188.1 0.3 1.8 1 1 0 1 1 1 1 Cytochrome P450 Endotoxin_N PF03945.9 EGC38662.1 - 0.061 12.7 0.1 0.12 11.7 0.1 1.4 1 0 0 1 1 1 0 delta endotoxin, N-terminal domain Acyl-CoA_dh_1 PF00441.19 EGC38663.1 - 1e-26 93.8 0.1 1.6e-26 93.2 0.1 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGC38663.1 - 3.9e-10 39.0 0.0 8.5e-10 38.0 0.0 1.5 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain Acyl-CoA_dh_2 PF08028.6 EGC38663.1 - 7e-07 29.5 0.0 1.2e-06 28.8 0.0 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGC38663.1 - 0.012 16.2 0.0 0.024 15.2 0.0 1.6 1 0 0 1 1 1 0 Acyl-CoA dehydrogenase, N-terminal domain ubiquitin PF00240.18 EGC38664.1 - 4.5e-11 41.9 0.3 7.9e-11 41.1 0.2 1.5 1 0 0 1 1 1 1 Ubiquitin family DUF2407_C PF13373.1 EGC38664.1 - 1.1e-06 28.5 0.1 2e-06 27.8 0.0 1.4 1 0 0 1 1 1 1 DUF2407 C-terminal domain Rad60-SLD PF11976.3 EGC38664.1 - 2e-05 24.2 0.1 3.5e-05 23.3 0.1 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC38664.1 - 0.00043 20.4 0.0 0.00068 19.7 0.0 1.4 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGC38664.1 - 0.00069 19.4 0.0 0.0011 18.8 0.0 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like BolA PF01722.13 EGC38666.1 - 8.1e-28 96.2 0.1 9.9e-28 95.9 0.1 1.1 1 0 0 1 1 1 1 BolA-like protein NTPase_I-T PF01931.13 EGC38667.1 - 9.3e-61 204.4 0.0 1.1e-60 204.2 0.0 1.0 1 0 0 1 1 1 1 Protein of unknown function DUF84 PRP38 PF03371.10 EGC38668.1 - 1.3e-36 125.8 1.6 1.8e-36 125.3 1.1 1.2 1 0 0 1 1 1 1 PRP38 family Spore_coat_CotO PF14153.1 EGC38669.1 - 4.6e-05 22.9 8.3 7.3e-05 22.2 5.8 1.3 1 0 0 1 1 1 1 Spore coat protein CotO VID27 PF08553.5 EGC38669.1 - 0.00082 17.7 13.5 0.0012 17.2 9.4 1.3 1 0 0 1 1 1 1 VID27 cytoplasmic protein FimP PF09766.4 EGC38669.1 - 0.0023 17.0 7.1 0.0036 16.4 4.9 1.2 1 0 0 1 1 1 1 Fms-interacting protein Nop14 PF04147.7 EGC38669.1 - 0.0024 15.9 25.2 0.0034 15.3 17.5 1.2 1 0 0 1 1 1 1 Nop14-like family MAM33 PF02330.11 EGC38669.1 - 0.0033 17.2 25.4 0.008 15.9 8.3 3.3 1 1 2 3 3 3 1 Mitochondrial glycoprotein SAPS PF04499.10 EGC38669.1 - 0.0075 14.9 3.3 0.011 14.4 2.3 1.3 1 0 0 1 1 1 1 SIT4 phosphatase-associated protein Ycf1 PF05758.7 EGC38669.1 - 0.011 13.4 6.3 0.013 13.2 4.4 1.1 1 0 0 1 1 1 0 Ycf1 Mpp10 PF04006.7 EGC38669.1 - 0.015 13.7 23.5 0.018 13.4 16.3 1.1 1 0 0 1 1 1 0 Mpp10 protein TFIIA PF03153.8 EGC38669.1 - 0.022 14.6 13.2 0.03 14.2 9.1 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit BUD22 PF09073.5 EGC38669.1 - 0.031 13.3 14.4 0.036 13.1 10.0 1.2 1 0 0 1 1 1 0 BUD22 Tim54 PF11711.3 EGC38669.1 - 0.057 11.9 8.8 0.059 11.9 5.4 1.4 2 0 0 2 2 2 0 Inner membrane protein import complex subunit Tim54 Prothymosin PF03247.9 EGC38669.1 - 0.063 13.4 44.1 0.13 12.4 30.6 1.5 1 0 0 1 1 1 0 Prothymosin/parathymosin family CDC45 PF02724.9 EGC38669.1 - 0.067 11.2 16.5 0.092 10.7 11.5 1.2 1 0 0 1 1 1 0 CDC45-like protein Daxx PF03344.10 EGC38669.1 - 0.57 8.5 30.6 0.82 8.0 21.2 1.2 1 0 0 1 1 1 0 Daxx Family SDA1 PF05285.7 EGC38669.1 - 0.65 9.2 24.5 0.9 8.7 17.0 1.1 1 0 0 1 1 1 0 SDA1 CENP-T PF15511.1 EGC38669.1 - 0.7 9.0 16.2 0.92 8.6 11.2 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Hid1 PF12722.2 EGC38669.1 - 0.82 7.2 7.1 0.98 7.0 4.9 1.1 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein YqfQ PF14181.1 EGC38669.1 - 0.99 9.4 16.0 2.1 8.3 11.1 1.5 1 0 0 1 1 1 0 YqfQ-like protein DUF1510 PF07423.6 EGC38669.1 - 1.2 8.4 23.8 1.8 7.8 16.5 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DUF4045 PF13254.1 EGC38669.1 - 2.4 7.3 8.2 4.2 6.5 5.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4045) NOA36 PF06524.7 EGC38669.1 - 2.6 7.2 15.3 4.4 6.4 10.6 1.3 1 0 0 1 1 1 0 NOA36 protein Herpes_UL25 PF01499.11 EGC38669.1 - 3.2 5.9 6.5 4.7 5.3 4.5 1.1 1 0 0 1 1 1 0 Herpesvirus UL25 family Paf1 PF03985.8 EGC38669.1 - 3.5 6.2 27.6 5.3 5.6 19.1 1.2 1 0 0 1 1 1 0 Paf1 Sporozoite_P67 PF05642.6 EGC38669.1 - 3.6 5.3 10.2 4.9 4.8 7.0 1.2 1 0 0 1 1 1 0 Sporozoite P67 surface antigen Usp PF00582.21 EGC38669.1 - 5.1 7.2 6.4 8.5 6.5 4.4 1.4 1 0 0 1 1 1 0 Universal stress protein family RRN3 PF05327.6 EGC38669.1 - 5.8 4.9 15.6 8 4.4 10.8 1.2 1 0 0 1 1 1 0 RNA polymerase I specific transcription initiation factor RRN3 RP-C_C PF11800.3 EGC38669.1 - 9.6 5.8 10.2 16 5.0 7.1 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Serinc PF03348.10 EGC38669.1 - 9.6 4.7 6.6 14 4.2 4.6 1.1 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF489 PF04356.7 EGC38670.1 - 0.00077 19.1 0.9 0.001 18.6 0.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF489) Sec8_exocyst PF04048.9 EGC38670.1 - 0.0018 17.9 3.6 0.0028 17.3 2.5 1.3 1 0 0 1 1 1 1 Sec8 exocyst complex component specific domain Spc7 PF08317.6 EGC38670.1 - 0.0023 16.6 8.4 0.0027 16.4 5.9 1.1 1 0 0 1 1 1 1 Spc7 kinetochore protein TBPIP PF07106.8 EGC38670.1 - 0.0044 16.5 7.0 0.0062 16.1 4.8 1.2 1 0 0 1 1 1 1 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) Cast PF10174.4 EGC38670.1 - 0.014 13.4 2.0 0.015 13.4 1.4 1.1 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone DUF3450 PF11932.3 EGC38670.1 - 0.017 14.4 0.4 0.022 14.0 0.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3450) Phage_GP20 PF06810.6 EGC38670.1 - 0.018 14.4 5.0 0.016 14.6 2.6 1.7 1 1 0 1 1 1 0 Phage minor structural protein GP20 DUF641 PF04859.7 EGC38670.1 - 0.021 14.5 1.9 0.021 14.5 1.3 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) ATG16 PF08614.6 EGC38670.1 - 0.029 14.2 7.0 0.14 11.9 2.6 2.1 2 0 0 2 2 2 0 Autophagy protein 16 (ATG16) PTS_EIIA_2 PF00359.17 EGC38670.1 - 0.03 14.0 0.3 0.049 13.3 0.2 1.4 1 0 0 1 1 1 0 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 DUF342 PF03961.8 EGC38670.1 - 0.21 9.9 7.5 0.23 9.8 5.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF342) DUF3972 PF13118.1 EGC38670.1 - 0.21 11.6 5.6 0.73 9.9 0.9 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3972) Troponin PF00992.15 EGC38670.1 - 0.7 9.9 6.3 0.21 11.6 2.2 1.6 1 1 0 1 1 1 0 Troponin IncA PF04156.9 EGC38670.1 - 2.7 7.5 4.9 4.7 6.7 3.4 1.6 1 1 0 1 1 1 0 IncA protein Vps51 PF08700.6 EGC38671.1 - 1.4e-25 88.9 0.6 1.4e-25 88.9 0.4 3.1 4 0 0 4 4 4 1 Vps51/Vps67 Sec5 PF15469.1 EGC38671.1 - 1.6e-21 76.8 8.8 1.6e-21 76.8 6.1 4.1 3 1 1 4 4 4 1 Exocyst complex component Sec5 Dor1 PF04124.7 EGC38671.1 - 1.7e-08 33.3 12.3 1.7e-08 33.3 8.5 2.3 3 1 0 3 3 3 1 Dor1-like family DUF2450 PF10475.4 EGC38671.1 - 6e-05 22.0 9.1 6e-05 22.0 6.3 2.2 2 0 0 2 2 2 1 Protein of unknown function N-terminal domain (DUF2450) COG2 PF06148.6 EGC38671.1 - 0.00018 21.3 9.7 0.0043 16.9 0.1 3.6 3 0 0 3 3 3 2 COG (conserved oligomeric Golgi) complex component, COG2 Cyclin PF08613.6 EGC38672.1 - 0.0035 17.7 6.0 0.0035 17.7 4.1 2.9 3 1 0 3 3 3 1 Cyclin TUSC2 PF15000.1 EGC38673.1 - 2.5 8.1 20.2 0.072 13.1 0.6 3.4 3 1 1 4 4 4 0 Tumour suppressor candidate 2 Ctr PF04145.10 EGC38675.1 - 4.9e-29 101.2 6.0 1.4e-28 99.7 4.1 1.7 1 1 0 1 1 1 1 Ctr copper transporter family DUF2897 PF11446.3 EGC38675.1 - 0.059 13.2 0.4 0.11 12.3 0.3 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2897) DUF92 PF01940.11 EGC38676.1 - 1.1e-66 224.2 4.2 1.3e-66 223.9 2.9 1.0 1 0 0 1 1 1 1 Integral membrane protein DUF92 Colicin_V PF02674.11 EGC38676.1 - 1.3 8.8 17.6 0.22 11.3 2.0 2.7 3 1 0 3 3 3 0 Colicin V production protein UPF0126 PF03458.8 EGC38676.1 - 6 6.5 11.3 4.2 7.0 0.1 3.9 3 1 0 3 3 3 0 UPF0126 domain PRMT5 PF05185.11 EGC38677.1 - 4e-173 576.4 3.9 5.3e-173 576.0 2.7 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase Met_10 PF02475.11 EGC38677.1 - 0.00012 21.6 0.0 0.00023 20.8 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_18 PF12847.2 EGC38677.1 - 0.029 14.9 0.0 0.066 13.7 0.0 1.6 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_26 PF13659.1 EGC38677.1 - 0.18 11.8 0.0 0.39 10.7 0.0 1.5 1 0 0 1 1 1 0 Methyltransferase domain Ribosomal_60s PF00428.14 EGC38678.1 - 7.2e-20 71.1 9.5 8.9e-20 70.8 6.6 1.1 1 0 0 1 1 1 1 60s Acidic ribosomal protein Gln-synt_C PF00120.19 EGC38679.1 - 6.5e-63 212.2 0.0 8.1e-63 211.9 0.0 1.1 1 0 0 1 1 1 1 Glutamine synthetase, catalytic domain Peptidase_M3 PF01432.15 EGC38680.1 - 3e-86 290.2 0.1 4.2e-86 289.8 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M3 Peptidase_M50B PF13398.1 EGC38680.1 - 0.2 11.0 0.1 0.35 10.2 0.1 1.3 1 0 0 1 1 1 0 Peptidase M50B-like OTU PF02338.14 EGC38682.1 - 3.3e-12 47.0 0.0 3.3e-12 47.0 0.0 3.1 2 1 0 2 2 2 1 OTU-like cysteine protease DUF3645 PF12359.3 EGC38682.1 - 0.076 12.1 0.1 14 4.8 0.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3645) PAT1 PF09770.4 EGC38682.1 - 0.38 8.9 57.8 0.53 8.4 40.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 EGC38682.1 - 0.95 8.9 19.4 1.5 8.2 13.5 1.3 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Med15 PF09606.5 EGC38682.1 - 9.3 4.2 80.2 13 3.8 55.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal ATP-synt_8 PF00895.15 EGC38684.1 - 3.3 7.9 7.6 1.9 8.7 2.7 2.6 2 1 0 2 2 2 0 ATP synthase protein 8 OTU PF02338.14 EGC38685.1 - 5.6e-12 46.3 0.0 5.6e-12 46.3 0.0 3.5 2 1 0 2 2 2 1 OTU-like cysteine protease Med15 PF09606.5 EGC38685.1 - 2 6.5 90.2 2.6 6.1 62.5 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal eIF-3_zeta PF05091.7 EGC38685.1 - 3.6 6.0 32.9 5.4 5.5 22.8 1.3 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) TFIIA PF03153.8 EGC38685.1 - 4 7.2 41.8 5.4 6.7 29.0 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Spc7_N PF15402.1 EGC38685.1 - 4.1 5.2 18.3 5.6 4.8 12.7 1.2 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 PAT1 PF09770.4 EGC38685.1 - 5 5.2 68.5 6.4 4.8 47.5 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Peptidase_C1 PF00112.18 EGC38686.1 - 3.8e-79 265.6 3.7 5.1e-79 265.2 2.5 1.1 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC38686.1 - 9.7e-14 51.3 3.6 1.6e-13 50.7 2.5 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC38686.1 - 0.00027 19.5 2.3 0.097 11.1 0.5 2.4 2 0 0 2 2 2 2 Peptidase C1-like family Serglycin PF04360.7 EGC38686.1 - 0.005 16.5 5.3 0.005 16.5 3.7 2.2 2 0 0 2 2 2 1 Serglycin DUF2524 PF10732.4 EGC38687.1 - 0.017 15.2 0.8 0.024 14.7 0.6 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF2524) Cep57_CLD PF14073.1 EGC38687.1 - 0.09 12.6 4.8 0.11 12.2 3.3 1.2 1 0 0 1 1 1 0 Centrosome localisation domain of Cep57 TACC PF05010.9 EGC38687.1 - 0.16 11.7 4.4 0.17 11.6 3.0 1.1 1 0 0 1 1 1 0 Transforming acidic coiled-coil-containing protein (TACC) CENP-F_leu_zip PF10473.4 EGC38688.1 - 0.002 18.0 3.8 0.002 18.0 2.6 2.9 2 1 0 2 2 2 1 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 TACC PF05010.9 EGC38688.1 - 0.003 17.3 24.9 0.77 9.4 10.7 2.2 1 1 1 2 2 2 2 Transforming acidic coiled-coil-containing protein (TACC) Toprim_Crpt PF13342.1 EGC38688.1 - 0.0054 16.3 0.9 0.12 12.0 0.2 3.0 2 1 0 2 2 2 1 C-terminal repeat of topoisomerase DUF106 PF01956.11 EGC38688.1 - 0.022 14.3 0.4 0.022 14.3 0.3 2.6 1 1 1 2 2 1 0 Integral membrane protein DUF106 Neur_chan_memb PF02932.11 EGC38688.1 - 0.054 13.3 2.0 0.074 12.9 1.4 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Peptidase_C10 PF01640.12 EGC38688.1 - 0.069 12.9 1.0 0.12 12.1 0.7 1.3 1 0 0 1 1 1 0 Peptidase C10 family DUF4600 PF15372.1 EGC38688.1 - 0.2 11.8 21.7 0.25 11.5 0.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) CcoS PF03597.10 EGC38688.1 - 0.21 11.0 1.4 0.56 9.7 0.0 2.1 2 0 0 2 2 2 0 Cytochrome oxidase maturation protein cbb3-type Cast PF10174.4 EGC38688.1 - 0.32 8.9 26.6 0.24 9.3 2.5 2.4 2 1 0 2 2 2 0 RIM-binding protein of the cytomatrix active zone Atg14 PF10186.4 EGC38688.1 - 3.6 6.4 19.4 4 6.3 8.1 2.0 2 0 0 2 2 2 0 UV radiation resistance protein and autophagy-related subunit 14 Dzip-like_N PF13815.1 EGC38688.1 - 5.6 6.7 17.6 0.063 13.0 4.9 2.2 2 1 0 2 2 2 0 Iguana/Dzip1-like DAZ-interacting protein N-terminal FNIP PF05725.7 EGC38689.1 - 7.8e-50 166.5 55.4 1.2e-09 37.9 0.2 9.9 3 3 9 12 12 12 12 FNIP Repeat C1_1 PF00130.17 EGC38690.1 - 3.6e-13 49.0 31.3 5.2e-07 29.2 7.2 2.4 2 0 0 2 2 2 2 Phorbol esters/diacylglycerol binding domain (C1 domain) DNA_pol_B PF00136.16 EGC38691.1 - 5.9e-134 447.3 0.1 8.3e-134 446.8 0.1 1.2 1 0 0 1 1 1 1 DNA polymerase family B DNA_pol_B_exo1 PF03104.14 EGC38691.1 - 4.1e-83 278.9 3.7 7.1e-83 278.1 2.6 1.4 1 0 0 1 1 1 1 DNA polymerase family B, exonuclease domain zf-C4pol PF14260.1 EGC38691.1 - 1.5e-22 79.3 9.7 3.4e-22 78.2 6.7 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta RNase_H_2 PF13482.1 EGC38691.1 - 0.00066 19.5 0.1 0.0023 17.7 0.0 2.0 1 1 0 1 1 1 1 RNase_H superfamily DNA_pol_B_exo2 PF10108.4 EGC38691.1 - 0.08 12.4 0.0 0.17 11.4 0.0 1.5 1 0 0 1 1 1 0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB TIP120 PF08623.5 EGC38692.1 - 3.2e-58 196.0 22.0 1.3e-56 190.7 0.2 6.4 6 1 1 7 7 7 2 TATA-binding protein interacting (TIP20) HEAT_2 PF13646.1 EGC38692.1 - 1e-16 60.9 1.9 0.0081 16.4 0.0 9.2 5 3 7 12 12 11 6 HEAT repeats HEAT PF02985.17 EGC38692.1 - 1.4e-15 55.9 19.5 0.83 9.9 0.0 13.8 16 0 0 16 16 15 4 HEAT repeat HEAT_EZ PF13513.1 EGC38692.1 - 5e-14 52.2 2.7 11 6.6 0.0 11.5 12 0 0 12 12 12 1 HEAT-like repeat ParcG PF10274.4 EGC38692.1 - 0.00011 22.2 19.2 0.05 13.5 0.0 7.0 7 1 0 7 7 7 2 Parkin co-regulated protein Vac14_Fab1_bd PF12755.2 EGC38692.1 - 0.00016 22.0 13.9 49 4.3 0.0 9.1 9 2 2 12 12 12 0 Vacuolar 14 Fab1-binding region V-ATPase_H_C PF11698.3 EGC38692.1 - 0.00027 20.8 12.3 11 5.9 0.1 7.1 6 2 2 8 8 8 1 V-ATPase subunit H DUF3437 PF11919.3 EGC38692.1 - 0.042 13.5 0.3 41 3.9 0.0 4.2 4 1 1 5 5 3 0 Domain of unknown function (DUF3437) DUF2457 PF10446.4 EGC38692.1 - 0.81 8.3 9.1 1.2 7.7 6.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Myc_N PF01056.13 EGC38692.1 - 1.7 7.7 5.6 3 6.9 3.9 1.3 1 0 0 1 1 1 0 Myc amino-terminal region NOA36 PF06524.7 EGC38692.1 - 5.2 6.2 9.6 10 5.2 6.6 1.4 1 0 0 1 1 1 0 NOA36 protein Nucleoplasmin PF03066.10 EGC38692.1 - 5.8 6.4 13.2 14 5.1 9.2 1.6 1 0 0 1 1 1 0 Nucleoplasmin tRNA-synt_His PF13393.1 EGC38693.1 - 1.4e-49 168.8 0.0 1.9e-49 168.4 0.0 1.2 1 0 0 1 1 1 1 Histidyl-tRNA synthetase tRNA-synt_2b PF00587.20 EGC38693.1 - 6.6e-18 64.8 0.0 1.4e-17 63.8 0.0 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC38693.1 - 3.2e-15 55.8 0.7 1.5e-14 53.7 0.0 2.3 2 0 0 2 2 2 1 Anticodon binding domain tRNA-synt_2 PF00152.15 EGC38693.1 - 5.3e-06 25.4 0.1 0.00014 20.7 0.0 2.4 2 0 0 2 2 2 1 tRNA synthetases class II (D, K and N) HHH_8 PF14716.1 EGC38693.1 - 0.0058 16.7 0.1 0.023 14.8 0.0 2.1 2 0 0 2 2 2 1 Helix-hairpin-helix domain HGTP_anticodon2 PF12745.2 EGC38693.1 - 0.018 14.1 0.2 0.018 14.1 0.2 1.6 2 0 0 2 2 2 0 Anticodon binding domain of tRNAs tRNA-synt_2d PF01409.15 EGC38693.1 - 0.028 13.6 0.4 0.27 10.3 0.1 2.5 2 1 0 2 2 2 0 tRNA synthetases class II core domain (F) PB1 PF00564.19 EGC38694.1 - 6.1e-07 29.0 0.1 1.2e-06 28.1 0.1 1.4 1 0 0 1 1 1 1 PB1 domain TLD PF07534.11 EGC38695.1 - 9.6e-28 96.9 1.2 9.6e-28 96.9 0.9 2.3 2 1 1 3 3 3 1 TLD RabGAP-TBC PF00566.13 EGC38695.1 - 1.7e-23 83.2 1.0 1.7e-23 83.2 0.7 2.3 2 1 0 2 2 2 1 Rab-GTPase-TBC domain DUF3439 PF11921.3 EGC38695.1 - 0.62 9.8 7.1 1.4 8.7 5.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) RNA_pol_Rpb2_6 PF00562.23 EGC38696.1 - 4.3e-115 384.5 0.0 1.4e-114 382.8 0.0 1.8 2 0 0 2 2 2 1 RNA polymerase Rpb2, domain 6 RNA_pol_Rpb2_1 PF04563.10 EGC38696.1 - 4.8e-54 182.3 0.2 4.8e-54 182.3 0.2 2.3 3 0 0 3 3 3 1 RNA polymerase beta subunit RNA_pol_Rpb2_7 PF04560.15 EGC38696.1 - 2.4e-29 101.4 0.1 7.5e-29 99.8 0.0 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 7 RNA_pol_Rpb2_2 PF04561.9 EGC38696.1 - 1.9e-24 86.1 0.3 1.9e-24 86.1 0.2 2.3 3 0 0 3 3 3 1 RNA polymerase Rpb2, domain 2 RNA_pol_Rpb2_4 PF04566.8 EGC38696.1 - 3.2e-22 78.1 0.3 9.1e-22 76.6 0.2 1.9 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 4 RNA_pol_Rpb2_3 PF04565.11 EGC38696.1 - 4.4e-17 61.5 1.6 2.7e-14 52.6 0.0 3.6 4 0 0 4 4 4 2 RNA polymerase Rpb2, domain 3 RNA_pol_Rpb2_5 PF04567.12 EGC38696.1 - 1.9e-11 43.7 0.4 4.5e-11 42.5 0.3 1.7 1 0 0 1 1 1 1 RNA polymerase Rpb2, domain 5 Hint PF01079.15 EGC38696.1 - 4.1e-05 22.9 0.0 7.7e-05 21.9 0.0 1.4 1 0 0 1 1 1 1 Hint module HABP4_PAI-RBP1 PF04774.10 EGC38697.1 - 2.8e-13 50.2 8.3 2.8e-13 50.2 5.7 4.2 2 2 1 3 3 3 1 Hyaluronan / mRNA binding family Neugrin PF06413.6 EGC38698.1 - 3.5e-10 40.0 1.3 3.5e-10 40.0 0.9 2.9 2 1 1 3 3 3 1 Neugrin MRP-L20 PF12824.2 EGC38698.1 - 4.7e-05 23.4 4.4 4.7e-05 23.4 3.0 2.6 1 1 1 2 2 2 1 Mitochondrial ribosomal protein subunit L20 HTH_24 PF13412.1 EGC38698.1 - 0.012 14.9 0.0 0.14 11.5 0.0 2.6 2 0 0 2 2 2 0 Winged helix-turn-helix DNA-binding Methyltransf_7 PF03492.10 EGC38701.1 - 0.092 11.4 0.0 0.093 11.4 0.0 1.1 1 0 0 1 1 1 0 SAM dependent carboxyl methyltransferase FNIP PF05725.7 EGC38702.1 - 1.9e-76 251.7 62.5 1.2e-16 60.3 1.6 10.6 6 2 4 11 11 11 11 FNIP Repeat LRR_5 PF13306.1 EGC38702.1 - 0.021 14.5 0.1 0.021 14.5 0.1 3.8 2 2 0 3 3 3 0 Leucine rich repeats (6 copies) DEAD PF00270.24 EGC38703.1 - 1.9e-40 138.1 0.0 2.4e-39 134.5 0.0 2.2 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38703.1 - 1.9e-28 98.1 0.0 5.1e-28 96.7 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Helicase_C_2 PF13307.1 EGC38703.1 - 0.00026 20.9 0.0 0.00083 19.3 0.0 1.8 2 0 0 2 2 2 1 Helicase C-terminal domain SecA_DEAD PF07517.9 EGC38703.1 - 0.00097 18.4 0.1 0.0015 17.8 0.0 1.4 1 1 0 1 1 1 1 SecA DEAD-like domain DUF1253 PF06862.7 EGC38703.1 - 0.05 11.9 0.0 0.17 10.2 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1253) Rrn6 PF10214.4 EGC38704.1 - 0.38 8.7 22.2 0.49 8.4 15.4 1.2 1 0 0 1 1 1 0 RNA polymerase I-specific transcription-initiation factor SOG2 PF10428.4 EGC38704.1 - 4.7 5.7 17.9 6 5.4 12.4 1.1 1 0 0 1 1 1 0 RAM signalling pathway protein EF-hand_4 PF12763.2 EGC38705.1 - 8.6e-30 102.5 25.2 1.1e-12 47.5 0.0 6.6 4 2 1 6 6 6 3 Cytoskeletal-regulatory complex EF hand EF-hand_7 PF13499.1 EGC38705.1 - 3.2e-11 43.1 3.6 0.00076 19.5 0.1 4.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC38705.1 - 4.6e-08 32.3 7.6 0.15 12.0 0.1 5.2 5 0 0 5 5 5 3 EF-hand domain EF-hand_1 PF00036.27 EGC38705.1 - 1.5e-07 30.2 8.4 1 8.8 0.2 5.7 5 0 0 5 5 5 4 EF hand EF-hand_8 PF13833.1 EGC38705.1 - 0.056 13.0 4.9 34 4.1 0.0 5.0 5 0 0 5 5 5 0 EF-hand domain pair Nop14 PF04147.7 EGC38706.1 - 2.6e-223 743.5 79.0 3.5e-223 743.1 54.7 1.1 1 0 0 1 1 1 1 Nop14-like family PPR_2 PF13041.1 EGC38707.1 - 0.004 17.0 3.0 11 6.0 0.1 4.5 4 0 0 4 4 4 1 PPR repeat family Peptidase_C23 PF05379.6 EGC38707.1 - 0.012 15.6 0.1 0.056 13.4 0.0 2.3 2 0 0 2 2 2 0 Carlavirus endopeptidase PPR PF01535.15 EGC38707.1 - 1.7 8.7 5.0 29 4.9 0.0 4.7 5 0 0 5 5 5 0 PPR repeat Ank_2 PF12796.2 EGC38708.1 - 6.4e-10 39.2 8.2 0.089 13.1 0.0 5.5 3 2 1 4 4 4 4 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC38708.1 - 4.3e-09 36.6 2.3 0.83 10.2 0.0 7.2 6 2 1 7 7 7 2 Ankyrin repeats (many copies) SR-25 PF10500.4 EGC38708.1 - 2.1e-05 24.1 11.8 2.1e-05 24.1 8.2 2.0 2 0 0 2 2 2 1 Nuclear RNA-splicing-associated protein Ank_3 PF13606.1 EGC38708.1 - 0.00017 21.5 1.8 7.3 7.1 0.0 6.8 7 0 0 7 7 7 1 Ankyrin repeat Ank PF00023.25 EGC38708.1 - 0.0019 17.9 0.1 7.1 6.6 0.0 4.4 5 0 0 5 5 5 1 Ankyrin repeat SWIM PF04434.12 EGC38708.1 - 0.0091 15.4 0.1 0.018 14.5 0.1 1.5 1 0 0 1 1 1 1 SWIM zinc finger Menin PF05053.8 EGC38708.1 - 0.015 13.4 13.0 0.025 12.7 9.0 1.2 1 0 0 1 1 1 0 Menin Phosphonate-bd PF12974.2 EGC38708.1 - 0.051 12.9 0.0 0.27 10.5 0.0 2.1 2 0 0 2 2 2 0 ABC transporter, phosphonate, periplasmic substrate-binding protein Neur_chan_memb PF02932.11 EGC38708.1 - 3.3 7.5 16.4 1.2 8.9 9.0 2.0 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region Auxin_canalis PF05703.6 EGC38708.1 - 3.9 7.2 8.0 11 5.8 5.5 1.6 1 0 0 1 1 1 0 Auxin canalisation DUF2201_N PF13203.1 EGC38708.1 - 5 6.2 10.5 8 5.5 7.3 1.2 1 0 0 1 1 1 0 Putative metallopeptidase domain Mito_carr PF00153.22 EGC38709.1 - 6.2e-53 176.4 6.7 2.1e-19 68.9 0.0 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein Spore_YtrH PF14034.1 EGC38709.1 - 1.6 8.7 5.0 0.88 9.5 0.5 2.7 3 1 1 4 4 4 0 Sporulation protein YtrH Ras PF00071.17 EGC38711.1 - 2.1e-19 69.4 1.8 4.3e-19 68.4 1.3 1.5 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC38711.1 - 9.2e-07 29.3 0.0 2e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38711.1 - 0.14 11.3 1.2 1.6 7.9 0.8 2.4 1 1 1 2 2 2 0 ADP-ribosylation factor family Pkinase_Tyr PF07714.12 EGC38713.1 - 5.2e-48 163.3 0.0 8.6e-48 162.6 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC38713.1 - 3.2e-44 151.0 0.0 2e-43 148.4 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EGC38713.1 - 3e-30 103.3 61.7 2.2e-10 39.9 5.0 9.1 6 2 3 9 9 9 6 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC38713.1 - 1.3e-20 72.9 59.2 1.4e-08 34.3 5.8 7.3 8 0 0 8 8 8 3 Leucine rich repeat RhoGEF PF00621.15 EGC38713.1 - 4.6e-15 55.9 8.2 7.4e-12 45.4 2.2 4.0 4 0 0 4 4 4 2 RhoGEF domain Miro PF08477.8 EGC38713.1 - 2.2e-12 47.5 0.7 1.5e-11 44.8 0.1 2.9 2 1 0 2 2 2 1 Miro-like protein LRR_1 PF00560.28 EGC38713.1 - 2.5e-12 44.9 48.9 0.021 14.7 0.1 13.6 13 0 0 13 13 13 6 Leucine Rich Repeat Ras PF00071.17 EGC38713.1 - 3.7e-12 45.9 0.0 3.1e-09 36.4 0.0 2.6 2 0 0 2 2 2 2 Ras family LRR_6 PF13516.1 EGC38713.1 - 5.5e-08 32.0 52.4 0.67 10.1 0.1 12.0 11 0 0 11 11 11 6 Leucine Rich repeat LRR_7 PF13504.1 EGC38713.1 - 0.079 13.1 37.3 0.21 11.9 0.1 10.3 10 0 0 10 10 10 0 Leucine rich repeat APH PF01636.18 EGC38713.1 - 1.7 8.3 0.1 6.3 6.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family CBM49 PF09478.5 EGC38714.1 - 1.8e-12 47.1 2.0 2.8e-12 46.5 1.4 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 DUF3430 PF11912.3 EGC38714.1 - 0.058 13.2 2.5 0.066 13.0 1.8 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF3430) PsbH PF00737.15 EGC38714.1 - 2.4 7.7 7.3 4.5 6.9 5.0 1.4 1 0 0 1 1 1 0 Photosystem II 10 kDa phosphoprotein E1-E2_ATPase PF00122.15 EGC38715.1 - 5.1e-20 71.4 0.0 1.7e-19 69.7 0.0 1.9 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC38715.1 - 3.5e-19 70.0 0.0 1.6e-18 67.9 0.0 2.2 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC38715.1 - 9.3e-19 68.3 0.0 1.7e-18 67.4 0.0 1.5 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC38715.1 - 2.2e-07 30.7 0.0 6.8e-07 29.1 0.0 1.8 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Cation_ATPase_C PF00689.16 EGC38715.1 - 0.0002 20.9 4.2 0.0002 20.9 2.9 2.7 4 0 0 4 4 4 1 Cation transporting ATPase, C-terminus Cation_ATPase_N PF00690.21 EGC38715.1 - 0.047 13.1 0.0 0.16 11.4 0.0 2.0 1 0 0 1 1 1 0 Cation transporter/ATPase, N-terminus LicD PF04991.8 EGC38715.1 - 0.072 13.1 3.4 0.11 12.6 0.5 2.3 2 0 0 2 2 2 0 LicD family Hydrolase_3 PF08282.7 EGC38715.1 - 0.42 10.1 7.0 0.2 11.1 0.1 3.2 2 1 1 3 3 3 0 haloacid dehalogenase-like hydrolase Kelch_4 PF13418.1 EGC38716.1 - 2.2e-50 168.2 15.4 5.4e-10 38.8 0.2 7.5 7 0 0 7 7 7 7 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC38716.1 - 3.1e-42 141.8 10.0 5.8e-08 32.6 0.1 7.1 7 0 0 7 7 7 5 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC38716.1 - 6.9e-36 121.5 12.7 8.7e-09 34.7 0.2 5.9 5 0 0 5 5 5 5 Kelch motif Kelch_6 PF13964.1 EGC38716.1 - 2.7e-35 119.0 15.8 4.1e-08 33.0 0.1 6.5 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC38716.1 - 2.7e-33 112.4 8.6 2.6e-09 36.4 0.1 6.1 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EGC38716.1 - 2.5e-31 107.1 11.8 1.7e-06 27.8 0.0 6.7 6 0 0 6 6 6 6 Kelch motif K-box PF01486.12 EGC38716.1 - 0.00017 21.3 2.4 0.00017 21.3 1.7 2.4 2 0 0 2 2 2 1 K-box region PQQ_3 PF13570.1 EGC38716.1 - 0.028 14.6 0.3 42 4.5 0.0 3.9 3 1 1 4 4 4 0 PQQ-like domain Glyco_hydro_18 PF00704.23 EGC38717.1 - 1.5e-18 67.3 3.3 2.4e-18 66.6 2.3 1.3 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 Mito_carr PF00153.22 EGC38719.1 - 8.6e-72 236.9 6.8 8.8e-25 86.2 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EGF_MSP1_1 PF12946.2 EGC38719.1 - 0.057 13.2 0.2 0.53 10.1 0.1 2.2 2 0 0 2 2 2 0 MSP1 EGF domain 1 Mob1_phocein PF03637.12 EGC38720.1 - 4.5e-68 228.3 0.0 5.5e-68 228.0 0.0 1.1 1 0 0 1 1 1 1 Mob1/phocein family DUF2053 PF09767.4 EGC38721.1 - 9.6e-23 80.9 10.5 1.3e-22 80.4 7.3 1.2 1 0 0 1 1 1 1 Predicted membrane protein (DUF2053) FNIP PF05725.7 EGC38722.1 - 2.5e-11 43.3 40.8 0.00094 19.0 0.1 9.4 7 2 2 9 9 9 5 FNIP Repeat Methyltransf_7 PF03492.10 EGC38723.1 - 5.4e-26 91.1 7.5 1.3e-25 89.8 5.2 1.5 1 1 0 1 1 1 1 SAM dependent carboxyl methyltransferase Metallophos_C PF14008.1 EGC38724.1 - 3.4e-13 49.4 0.4 6.6e-13 48.5 0.3 1.5 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C Metallophos PF00149.23 EGC38724.1 - 4.8e-13 48.9 5.7 8.7e-13 48.1 4.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PhoD PF09423.5 EGC38724.1 - 1.5e-07 30.3 0.1 3.3e-07 29.2 0.0 1.5 2 0 0 2 2 2 1 PhoD-like phosphatase Metallophos_2 PF12850.2 EGC38724.1 - 1.5e-05 24.8 0.0 3.5e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain Metallophos PF00149.23 EGC38726.1 - 4.4e-18 65.3 7.2 1.4e-17 63.7 5.0 1.8 1 1 0 1 1 1 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGC38726.1 - 3.1e-14 52.8 1.8 4.6e-14 52.2 0.4 2.0 2 0 0 2 2 2 1 Iron/zinc purple acid phosphatase-like protein C Metallophos_2 PF12850.2 EGC38726.1 - 4.6e-08 33.0 0.0 9.1e-08 32.0 0.0 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase superfamily domain PhoD PF09423.5 EGC38726.1 - 1.2e-07 30.6 1.2 2.3e-07 29.7 0.8 1.4 1 0 0 1 1 1 1 PhoD-like phosphatase Metallophos PF00149.23 EGC38727.1 - 1.3e-14 54.0 8.7 1.3e-14 54.0 6.0 1.9 2 1 0 2 2 2 1 Calcineurin-like phosphoesterase Metallophos_C PF14008.1 EGC38727.1 - 1e-12 47.8 1.1 2.6e-12 46.6 0.8 1.7 1 0 0 1 1 1 1 Iron/zinc purple acid phosphatase-like protein C PhoD PF09423.5 EGC38727.1 - 5.9e-09 35.0 1.1 2.5e-07 29.6 0.3 2.1 2 0 0 2 2 2 2 PhoD-like phosphatase Metallophos_2 PF12850.2 EGC38727.1 - 1.4e-08 34.6 0.0 3.6e-08 33.3 0.0 1.6 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase superfamily domain WD40 PF00400.27 EGC38728.1 - 5.6e-07 29.2 5.4 0.32 10.9 0.1 5.8 6 0 0 6 6 6 4 WD domain, G-beta repeat WD40 PF00400.27 EGC38729.1 - 1.1e-41 139.2 10.9 3.8e-08 32.9 0.0 7.2 7 0 0 7 7 7 6 WD domain, G-beta repeat BRCA-2_OB1 PF09103.5 EGC38730.1 - 1.2e-33 115.2 0.0 6e-33 113.0 0.0 2.2 1 1 0 1 1 1 1 BRCA2, oligonucleotide/oligosaccharide-binding, domain 1 BRCA-2_helical PF09169.5 EGC38730.1 - 2.2e-17 63.2 1.5 9.4e-16 57.9 0.1 2.7 1 1 1 2 2 2 2 BRCA2, helical ComC PF03047.9 EGC38731.1 - 0.16 11.4 1.5 5 6.6 0.0 2.5 2 0 0 2 2 2 0 COMC family KIAA1430 PF13879.1 EGC38731.1 - 0.22 11.9 3.5 0.29 11.5 2.4 1.4 1 1 0 1 1 1 0 KIAA1430 homologue DUF1736 PF08409.6 EGC38732.1 - 1.4e-22 79.0 2.7 6.9e-22 76.8 1.9 2.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1736) TPR_11 PF13414.1 EGC38732.1 - 6.5e-16 57.7 10.3 1.1e-06 28.1 0.2 5.2 2 1 3 5 5 5 5 TPR repeat TPR_12 PF13424.1 EGC38732.1 - 3.6e-14 52.4 3.8 1.8e-07 30.9 0.0 4.0 3 1 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC38732.1 - 8.5e-13 47.3 7.8 9.7e-06 24.9 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC38732.1 - 2.3e-12 45.8 4.6 1.8e-05 24.2 0.0 5.5 5 0 0 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38732.1 - 3.5e-12 45.1 5.3 0.0013 18.3 0.0 5.9 5 0 0 5 5 5 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38732.1 - 3.5e-10 39.6 1.4 0.16 12.4 0.0 4.8 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGC38732.1 - 3.6e-08 32.9 3.8 0.13 12.4 0.0 5.4 5 0 0 5 5 4 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC38732.1 - 2.7e-06 27.5 0.0 3.4 8.5 0.0 4.6 4 1 2 6 6 4 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC38732.1 - 5.7e-05 22.6 0.6 7.6 6.6 0.0 4.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38732.1 - 7.1e-05 23.0 0.3 1.5 9.2 0.0 4.4 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGC38732.1 - 0.00029 20.6 0.0 0.051 13.5 0.0 3.6 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38732.1 - 0.00058 20.4 0.0 3.8 8.2 0.0 3.5 3 0 0 3 3 3 1 Tetratricopeptide repeat PBP1_TM PF14812.1 EGC38732.1 - 0.047 13.9 4.7 0.51 10.6 0.3 3.2 3 0 0 3 3 2 0 Transmembrane domain of transglycosylase PBP1 at N-terminal Mucin PF01456.12 EGC38732.1 - 0.21 11.3 11.2 0.51 10.1 7.8 1.6 1 0 0 1 1 1 0 Mucin-like glycoprotein Copine PF07002.11 EGC38734.1 - 1.8e-50 170.5 0.3 6.3e-50 168.7 0.2 1.8 2 0 0 2 2 2 1 Copine C2 PF00168.25 EGC38734.1 - 2.5e-22 78.4 1.7 3.5e-11 42.7 0.1 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC38734.1 - 3e-07 30.4 0.0 5.7e-07 29.5 0.0 1.4 1 0 0 1 1 1 1 vWA found in TerF C terminus RteC PF09357.5 EGC38734.1 - 0.049 13.4 0.5 0.098 12.5 0.3 1.4 1 0 0 1 1 1 0 RteC protein OAD_gamma PF04277.8 EGC38735.1 - 0.042 14.2 0.0 0.045 14.1 0.0 1.2 1 0 0 1 1 1 0 Oxaloacetate decarboxylase, gamma chain Yip1 PF04893.12 EGC38735.1 - 0.081 12.4 0.0 0.1 12.1 0.0 1.0 1 0 0 1 1 1 0 Yip1 domain DUF4269 PF14091.1 EGC38736.1 - 3.2e-54 182.9 0.6 3.8e-54 182.7 0.4 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4269) DKNYY PF13644.1 EGC38736.1 - 0.091 13.0 4.8 0.3 11.3 0.7 2.1 2 0 0 2 2 2 0 DKNYY family DUF1789 PF08748.6 EGC38737.1 - 0.078 13.0 0.0 0.087 12.9 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1789) DS PF01916.12 EGC38738.1 - 4.3e-135 449.6 0.0 5.1e-135 449.3 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase RCC1_2 PF13540.1 EGC38739.1 - 2.1e-26 90.9 5.6 1.9e-10 40.0 0.5 5.4 5 0 0 5 5 5 4 Regulator of chromosome condensation (RCC1) repeat RCC1 PF00415.13 EGC38739.1 - 1.9e-21 75.9 0.2 3e-05 24.1 0.0 7.2 7 1 0 7 7 7 4 Regulator of chromosome condensation (RCC1) repeat BTB PF00651.26 EGC38739.1 - 1.7e-07 31.1 7.8 8.5e-07 28.9 0.1 4.0 4 0 0 4 4 4 1 BTB/POZ domain zf-TRAF PF02176.13 EGC38740.1 - 1.9e-20 72.9 17.7 2.4e-14 53.4 5.3 4.4 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 EGC38740.1 - 7.9e-07 28.6 11.7 7.9e-07 28.6 8.1 3.7 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38740.1 - 4.5e-06 26.5 14.7 4.5e-06 26.5 10.2 4.0 2 1 2 4 4 4 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC38740.1 - 6e-06 26.0 18.3 0.00016 21.3 0.7 3.8 1 1 3 4 4 4 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC38740.1 - 0.00012 21.8 12.5 0.00012 21.8 8.7 3.2 3 1 0 3 3 3 1 Ring finger domain XkdN PF08890.6 EGC38740.1 - 0.031 14.0 3.4 0.066 12.9 2.4 1.5 1 0 0 1 1 1 0 Phage XkdN-like protein YkuI_C PF10388.4 EGC38740.1 - 0.07 12.8 0.0 0.07 12.8 0.0 3.2 2 2 1 3 3 3 0 EAL-domain associated signalling protein domain Carb_bind PF10645.4 EGC38741.1 - 0.16 11.7 3.8 1.6 8.6 2.6 2.1 1 1 0 1 1 1 0 Carbohydrate binding TRM13 PF05206.9 EGC38742.1 - 4.7e-67 225.9 9.6 4.7e-67 225.9 6.6 2.6 2 1 0 2 2 2 1 Methyltransferase TRM13 zf-TRM13_CCCH PF11722.3 EGC38742.1 - 3e-09 36.0 5.0 3e-09 36.0 3.5 2.2 2 0 0 2 2 2 1 CCCH zinc finger in TRM13 protein zf-U11-48K PF05253.7 EGC38742.1 - 3.2e-08 33.1 1.1 1e-07 31.4 0.7 2.0 1 0 0 1 1 1 1 U11-48K-like CHHC zinc finger Methyltransf_12 PF08242.7 EGC38742.1 - 0.7 10.3 0.0 0.7 10.3 0.0 3.7 4 0 0 4 4 4 0 Methyltransferase domain Glyoxalase_3 PF13468.1 EGC38743.1 - 0.021 14.7 0.0 0.035 14.0 0.0 1.4 1 0 0 1 1 1 0 Glyoxalase-like domain KIX PF02172.11 EGC38743.1 - 0.043 13.8 0.1 0.067 13.2 0.1 1.3 1 0 0 1 1 1 0 KIX domain Tmemb_9 PF05434.6 EGC38745.1 - 0.031 14.0 0.8 0.068 12.9 0.5 1.5 1 0 0 1 1 1 0 TMEM9 NAD_binding_10 PF13460.1 EGC38746.1 - 1.2e-11 45.0 0.0 1.6e-11 44.5 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC38746.1 - 0.00042 19.3 0.0 0.0011 17.9 0.0 1.7 2 0 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EGC38746.1 - 0.0028 17.9 0.1 0.0089 16.3 0.0 1.8 2 0 0 2 2 2 1 Semialdehyde dehydrogenase, NAD binding domain Epimerase PF01370.16 EGC38746.1 - 0.0046 16.4 0.0 0.0072 15.7 0.0 1.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family RRM_1 PF00076.17 EGC38747.1 - 1.5e-81 267.9 5.3 1.1e-21 76.2 0.2 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38747.1 - 2.6e-61 203.5 1.2 1.6e-16 60.0 0.0 4.2 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38747.1 - 5.4e-45 151.0 0.2 6.8e-10 38.6 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) PABP PF00658.13 EGC38747.1 - 1.3e-19 69.6 0.1 8.2e-19 67.0 0.1 2.2 2 0 0 2 2 2 1 Poly-adenylate binding protein, unique domain Nup35_RRM PF05172.8 EGC38747.1 - 5.3e-10 38.9 0.0 0.0034 17.1 0.0 3.5 3 0 0 3 3 3 2 Nup53/35/40-type RNA recognition motif Nup35_RRM_2 PF14605.1 EGC38747.1 - 5e-07 29.3 0.0 0.55 10.0 0.0 3.5 3 0 0 3 3 3 3 Nup53/35/40-type RNA recognition motif RRM_3 PF08777.6 EGC38747.1 - 2.9e-06 27.0 0.6 0.33 10.8 0.1 4.1 4 0 0 4 4 4 2 RNA binding motif OB_RNB PF08206.6 EGC38747.1 - 0.00015 21.1 1.7 0.026 14.0 0.0 3.3 3 0 0 3 3 3 1 Ribonuclease B OB domain Limkain-b1 PF11608.3 EGC38747.1 - 0.002 17.8 1.7 3.8 7.3 0.0 4.3 4 1 0 4 4 4 1 Limkain b1 KH_1 PF00013.24 EGC38748.1 - 2.8e-07 30.0 0.3 7.8e-07 28.6 0.2 1.8 1 1 0 1 1 1 1 KH domain KH_3 PF13014.1 EGC38748.1 - 2e-05 24.0 1.4 7e-05 22.3 1.0 2.0 1 1 0 1 1 1 1 KH domain FNIP PF05725.7 EGC38749.1 - 2.2e-07 30.6 30.9 0.0039 17.1 0.1 9.0 7 4 2 9 9 9 7 FNIP Repeat PP_kinase_C PF13090.1 EGC38750.1 - 4.6e-138 459.6 0.3 7.6e-138 458.9 0.2 1.3 1 0 0 1 1 1 1 Polyphosphate kinase C-terminal domain PP_kinase PF02503.12 EGC38750.1 - 2e-64 216.9 3.3 3.3e-64 216.1 2.3 1.4 1 0 0 1 1 1 1 Polyphosphate kinase middle domain PP_kinase_N PF13089.1 EGC38750.1 - 3.6e-22 78.5 0.7 1e-21 77.0 0.5 1.8 1 0 0 1 1 1 1 Polyphosphate kinase N-terminal domain PLDc_2 PF13091.1 EGC38750.1 - 3.5e-09 36.4 0.3 0.00053 19.7 0.1 2.5 2 0 0 2 2 2 2 PLD-like domain RE_NgoFVII PF09565.5 EGC38750.1 - 0.00046 19.2 0.0 0.00093 18.2 0.0 1.4 1 0 0 1 1 1 1 NgoFVII restriction endonuclease p450 PF00067.17 EGC38751.1 - 1.4e-87 294.1 0.1 1.6e-87 293.9 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 ABC_membrane PF00664.18 EGC38752.1 - 6.5e-54 183.1 25.9 6.5e-54 183.1 17.9 2.7 2 1 0 2 2 2 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGC38752.1 - 1.2e-33 116.3 0.4 3.1e-33 114.9 0.0 2.0 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGC38752.1 - 4.5e-05 22.7 3.3 0.00064 19.0 1.3 2.5 2 2 0 2 2 2 1 RecF/RecN/SMC N terminal domain ABC_ATPase PF09818.4 EGC38752.1 - 7.2e-05 21.5 0.1 0.083 11.4 0.1 2.2 2 0 0 2 2 2 2 Predicted ATPase of the ABC class AAA_29 PF13555.1 EGC38752.1 - 0.0023 17.4 0.1 0.0082 15.6 0.1 1.9 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC38752.1 - 0.0098 15.0 0.0 0.021 14.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC38752.1 - 0.035 14.2 0.0 0.15 12.2 0.0 2.1 1 1 0 1 1 1 0 AAA domain AAA_11 PF13086.1 EGC38752.1 - 0.044 13.3 0.0 0.044 13.3 0.0 2.5 3 0 0 3 3 3 0 AAA domain AAA_25 PF13481.1 EGC38752.1 - 0.16 11.3 0.5 0.53 9.6 0.0 2.0 2 0 0 2 2 2 0 AAA domain Glyco_hydro_18 PF00704.23 EGC38753.1 - 3e-07 30.2 0.0 3.6e-07 29.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 Glyco_hydro_85 PF03644.8 EGC38753.1 - 0.014 14.5 0.0 0.019 14.1 0.0 1.2 1 0 0 1 1 1 0 Glycosyl hydrolase family 85 NLPC_P60 PF00877.14 EGC38754.1 - 3.4e-11 42.8 0.1 4.5e-11 42.5 0.1 1.2 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.8 EGC38754.1 - 0.00078 19.0 1.8 0.00078 19.0 1.2 1.4 2 0 0 2 2 2 1 Bacteriophage peptidoglycan hydrolase Pkinase PF00069.20 EGC38755.1 - 2e-41 141.8 20.7 7.2e-23 81.0 3.2 3.5 3 1 0 3 3 3 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38755.1 - 1.5e-21 76.6 1.8 4.8e-10 38.9 0.5 2.7 2 0 0 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC38755.1 - 0.0065 15.4 0.2 0.032 13.1 0.0 2.2 3 0 0 3 3 3 1 Kinase-like Kdo PF06293.9 EGC38755.1 - 0.043 12.8 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC38755.1 - 0.074 12.7 0.1 0.27 10.9 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family DUF2076 PF09849.4 EGC38756.1 - 9.5e-06 25.8 5.0 1.2e-05 25.5 3.4 1.2 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2076) CHCH PF06747.8 EGC38756.1 - 0.0014 18.4 4.2 0.0026 17.6 2.9 1.4 1 0 0 1 1 1 1 CHCH domain Pet191_N PF10203.4 EGC38756.1 - 0.018 15.0 1.0 0.032 14.2 0.7 1.4 1 0 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 PSI_PSAK PF01241.13 EGC38756.1 - 0.071 13.1 1.3 0.078 13.0 0.3 1.6 2 0 0 2 2 2 0 Photosystem I psaG / psaK Rick_17kDa_Anti PF05433.10 EGC38756.1 - 0.26 10.9 8.4 0.45 10.2 5.8 1.3 1 0 0 1 1 1 0 Glycine zipper 2TM domain Gly-zipper_OmpA PF13436.1 EGC38756.1 - 0.64 9.6 9.7 0.49 10.0 5.3 2.1 1 1 1 2 2 2 0 Glycine-zipper containing OmpA-like membrane domain DEC-1_N PF04625.8 EGC38756.1 - 1.5 7.3 10.5 1.8 7.1 7.3 1.1 1 0 0 1 1 1 0 DEC-1 protein, N-terminal region Archease PF01951.11 EGC38757.1 - 2.4e-45 153.8 3.4 2.7e-45 153.6 2.3 1.0 1 0 0 1 1 1 1 Archease protein family (MTH1598/TM1083) UPF0150 PF03681.10 EGC38757.1 - 0.099 12.2 0.0 0.2 11.3 0.0 1.4 1 0 0 1 1 1 0 Uncharacterised protein family (UPF0150) Ras PF00071.17 EGC38758.1 - 1.4e-36 125.2 0.0 1.7e-36 125.0 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38758.1 - 9.2e-13 48.7 0.0 1.3e-12 48.2 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38758.1 - 1.8e-09 37.0 0.0 2.3e-09 36.7 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC38758.1 - 0.0011 18.4 0.0 0.71 9.2 0.0 2.1 2 0 0 2 2 2 2 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC38758.1 - 0.007 15.5 0.1 0.02 14.1 0.0 1.7 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC38758.1 - 0.024 14.6 0.1 0.1 12.5 0.1 2.1 1 1 0 1 1 1 0 50S ribosome-binding GTPase NLPC_P60 PF00877.14 EGC38759.1 - 1.1e-10 41.1 0.0 1.7e-10 40.6 0.0 1.3 1 0 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.8 EGC38759.1 - 0.0044 16.6 0.8 0.009 15.6 0.5 1.6 1 1 0 1 1 1 1 Bacteriophage peptidoglycan hydrolase FNIP PF05725.7 EGC38760.1 - 5.9e-38 128.5 27.5 9.4e-17 60.7 0.8 7.6 5 2 3 8 8 8 7 FNIP Repeat DUF1769 PF08588.5 EGC38760.1 - 0.035 14.0 6.2 78 3.3 0.0 5.2 2 2 3 5 5 5 0 Protein of unknown function (DUF1769) EGF_2 PF07974.8 EGC38761.1 - 1.4e-15 57.1 118.8 0.00075 19.5 6.2 8.0 5 2 2 7 7 7 6 EGF-like domain Laminin_EGF PF00053.19 EGC38761.1 - 0.0059 16.5 101.1 0.082 12.8 5.1 7.2 2 2 4 7 7 7 4 Laminin EGF-like (Domains III and V) SKG6 PF08693.5 EGC38761.1 - 0.088 12.1 3.5 0.21 10.9 2.0 1.9 2 0 0 2 2 2 0 Transmembrane alpha-helix domain LRR_1 PF00560.28 EGC38761.1 - 3.7 7.9 14.3 2 8.7 0.2 5.8 6 0 0 6 6 6 0 Leucine Rich Repeat WD40 PF00400.27 EGC38762.1 - 2.6e-53 176.1 20.7 2.4e-09 36.7 0.2 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat DUF3312 PF11768.3 EGC38762.1 - 0.038 12.2 0.0 0.15 10.2 0.0 1.6 1 1 1 2 2 2 0 Protein of unknown function (DUF3312) ketoacyl-synt PF00109.21 EGC38764.1 - 4e-64 216.5 0.0 5.9e-64 215.9 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Ketoacyl-synt_C PF02801.17 EGC38764.1 - 4.8e-32 110.2 0.0 2.1e-31 108.2 0.0 2.1 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38764.1 - 8.1e-23 81.0 0.0 1.6e-22 80.0 0.0 1.5 1 0 0 1 1 1 1 KR domain Acyl_transf_1 PF00698.16 EGC38764.1 - 7.6e-22 78.0 0.0 6.5e-17 61.8 0.0 2.6 2 1 1 3 3 3 2 Acyl transferase domain Methyltransf_12 PF08242.7 EGC38764.1 - 4.5e-21 75.1 0.0 4.5e-21 75.1 0.0 4.9 5 0 0 5 5 4 1 Methyltransferase domain PS-DH PF14765.1 EGC38764.1 - 1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC38764.1 - 7.9e-15 55.1 0.0 1.6e-14 54.2 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38764.1 - 5.2e-08 33.8 0.0 1.1e-07 32.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC38764.1 - 6.4e-07 29.1 0.1 1.4e-06 27.9 0.1 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC38764.1 - 2.1e-05 24.3 0.0 4.7e-05 23.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC38764.1 - 2.8e-05 24.5 0.0 0.00014 22.2 0.0 2.3 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC38764.1 - 3.3e-05 23.0 0.0 7.1e-05 21.9 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC38764.1 - 6.2e-05 23.5 0.0 0.00042 20.8 0.0 2.5 3 0 0 3 3 1 1 Methyltransferase domain PP-binding PF00550.20 EGC38764.1 - 9.1e-05 22.6 0.2 0.00028 21.1 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site FNIP PF05725.7 EGC38765.1 - 1.9e-78 258.1 88.1 1.1e-08 34.8 0.9 15.1 7 3 11 18 18 18 17 FNIP Repeat LRR_2 PF07723.8 EGC38765.1 - 0.62 10.6 4.0 11 6.6 0.0 4.3 3 0 0 3 3 3 0 Leucine Rich Repeat ketoacyl-synt PF00109.21 EGC38766.1 - 3.4e-61 206.9 0.0 6.2e-61 206.0 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC38766.1 - 2.4e-48 165.1 0.0 6.2e-48 163.7 0.0 1.7 2 0 0 2 2 2 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC38766.1 - 9.9e-32 109.2 0.0 4e-31 107.3 0.0 2.0 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC38766.1 - 3.9e-23 82.0 0.0 8.2e-23 80.9 0.0 1.5 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC38766.1 - 4.3e-22 78.4 3.3 4.7e-21 75.1 0.0 4.1 4 0 0 4 4 3 1 Methyltransferase domain PS-DH PF14765.1 EGC38766.1 - 7.9e-19 67.9 0.0 1.2e-18 67.2 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC38766.1 - 2.4e-14 53.6 0.0 4.8e-14 52.6 0.0 1.6 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC38766.1 - 9.9e-10 39.3 0.0 2.1e-09 38.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_23 PF13489.1 EGC38766.1 - 5.6e-06 26.1 0.0 1.6e-05 24.7 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain ADH_N PF08240.7 EGC38766.1 - 6e-06 25.9 0.1 1.3e-05 24.8 0.1 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_11 PF08241.7 EGC38766.1 - 4.3e-05 23.9 0.0 0.00021 21.6 0.0 2.3 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC38766.1 - 5.6e-05 23.6 0.0 0.0002 21.9 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Thiolase_N PF00108.18 EGC38766.1 - 0.00016 20.7 0.1 0.00035 19.6 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_31 PF13847.1 EGC38766.1 - 0.00042 19.9 3.5 0.00054 19.5 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain PP-binding PF00550.20 EGC38766.1 - 0.00044 20.4 0.1 0.0012 19.0 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site DS PF01916.12 EGC38767.1 - 2.5e-130 433.9 0.0 3e-130 433.7 0.0 1.0 1 0 0 1 1 1 1 Deoxyhypusine synthase DEAD PF00270.24 EGC38768.1 - 8.2e-35 119.7 0.1 3.8e-34 117.6 0.1 2.2 1 1 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38768.1 - 9.2e-21 73.5 0.0 2.7e-20 72.0 0.0 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC38768.1 - 8.2e-10 38.8 0.1 8.2e-10 38.8 0.0 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_22 PF13401.1 EGC38768.1 - 0.0012 18.9 0.1 0.0059 16.7 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF2457 PF10446.4 EGC38768.1 - 0.014 14.1 12.1 0.021 13.6 8.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) T2SE PF00437.15 EGC38768.1 - 0.047 12.5 0.1 0.28 10.0 0.0 2.2 3 0 0 3 3 3 0 Type II/IV secretion system protein DUF4611 PF15387.1 EGC38768.1 - 0.75 9.9 10.4 0.92 9.6 6.1 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4611) DUF1517 PF07466.6 EGC38769.1 - 0.4 9.6 2.9 0.96 8.3 2.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1517) Xpo1 PF08389.7 EGC38770.1 - 1.7e-12 47.4 1.8 1.7e-12 47.4 1.3 5.1 4 2 3 7 7 7 1 Exportin 1-like protein DUF948 PF06103.6 EGC38771.1 - 0.066 13.0 0.0 0.32 10.8 0.0 2.2 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF948) SET PF00856.23 EGC38772.1 - 6.9e-15 55.7 0.0 2.5e-14 53.9 0.0 1.9 1 1 0 1 1 1 1 SET domain SSP160 PF06933.6 EGC38772.1 - 0.024 12.6 4.4 0.033 12.1 3.1 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Pex14_N PF04695.8 EGC38772.1 - 0.084 12.9 0.7 0.15 12.1 0.5 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Peptidase_C97 PF05903.9 EGC38773.1 - 2e-05 24.3 1.4 3.6e-05 23.5 0.9 1.5 1 1 0 1 1 1 1 PPPDE putative peptidase domain Kunitz_BPTI PF00014.18 EGC38773.1 - 0.067 13.3 0.0 0.14 12.3 0.0 1.5 1 0 0 1 1 1 0 Kunitz/Bovine pancreatic trypsin inhibitor domain LRAT PF04970.8 EGC38773.1 - 0.1 12.5 1.0 0.5 10.3 0.7 2.0 1 1 0 1 1 1 0 Lecithin retinol acyltransferase Peptidase_C97 PF05903.9 EGC38774.1 - 0.00023 20.9 0.4 0.00028 20.6 0.3 1.2 1 0 0 1 1 1 1 PPPDE putative peptidase domain LRAT PF04970.8 EGC38774.1 - 0.052 13.5 0.7 0.29 11.0 0.5 2.1 1 1 0 1 1 1 0 Lecithin retinol acyltransferase DUF4348 PF14254.1 EGC38775.1 - 0.0081 15.3 0.3 0.014 14.5 0.2 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4348) DPBB_1 PF03330.13 EGC38776.1 - 0.0096 15.9 0.4 0.025 14.5 0.3 1.7 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pkinase PF00069.20 EGC38777.1 - 8.7e-55 185.6 0.1 1.3e-53 181.8 0.0 2.7 3 0 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC38777.1 - 9.7e-36 123.1 0.0 2.1e-35 122.0 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase RhoGAP PF00620.22 EGC38777.1 - 1e-30 106.3 0.1 1e-30 106.3 0.1 2.3 3 0 0 3 3 3 1 RhoGAP domain Kinase-like PF14531.1 EGC38777.1 - 0.0012 17.9 0.0 0.0037 16.2 0.0 1.8 1 1 0 1 1 1 1 Kinase-like DUF948 PF06103.6 EGC38777.1 - 0.077 12.8 0.5 0.26 11.1 0.2 2.0 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF948) PH PF00169.24 EGC38777.1 - 0.75 10.0 14.4 51 4.1 10.0 2.8 1 1 0 1 1 1 0 PH domain Chromo PF00385.19 EGC38778.1 - 1.7e-14 53.1 2.9 2.4e-14 52.7 2.0 1.2 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC38778.1 - 0.07 12.8 0.4 0.11 12.1 0.3 1.5 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain FNIP PF05725.7 EGC38779.1 - 2.7e-21 75.2 11.7 5.9e-11 42.1 0.4 3.1 3 0 0 3 3 3 3 FNIP Repeat DNA_topoisoIV PF00521.15 EGC38781.1 - 1.6e-116 389.6 0.2 1.6e-116 389.6 0.1 2.2 2 0 0 2 2 2 1 DNA gyrase/topoisomerase IV, subunit A DNA_gyraseB PF00204.20 EGC38781.1 - 3.6e-30 104.4 0.7 3.6e-30 104.4 0.5 2.4 2 0 0 2 2 2 1 DNA gyrase B Toprim PF01751.17 EGC38781.1 - 2.1e-12 46.8 0.0 1.2e-11 44.4 0.0 2.4 1 0 0 1 1 1 1 Toprim domain HATPase_c PF02518.21 EGC38781.1 - 3.4e-08 33.1 0.1 8e-08 31.9 0.0 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Kelch_3 PF13415.1 EGC38782.1 - 6.5e-39 131.2 7.9 4.7e-11 42.5 0.1 5.9 5 0 0 5 5 5 4 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC38782.1 - 6.8e-39 131.3 15.3 4e-10 39.3 0.2 6.7 5 1 1 6 6 6 5 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC38782.1 - 4.2e-35 118.4 22.7 1.4e-10 40.8 0.3 6.9 5 1 2 7 7 7 6 Kelch motif RasGEF PF00617.14 EGC38782.1 - 5.4e-35 120.8 0.5 2.1e-34 118.9 0.5 1.9 2 0 0 2 2 2 1 RasGEF domain Kelch_5 PF13854.1 EGC38782.1 - 1.2e-29 101.7 15.6 9.9e-07 28.5 0.1 6.6 6 0 0 6 6 6 6 Kelch motif Kelch_1 PF01344.20 EGC38782.1 - 1.7e-27 94.7 10.5 2.5e-06 26.9 0.2 5.7 5 0 0 5 5 5 5 Kelch motif RasGEF_N PF00618.15 EGC38782.1 - 1.5e-24 86.0 0.3 5.2e-24 84.3 0.0 2.1 2 0 0 2 2 2 1 RasGEF N-terminal motif Kelch_2 PF07646.10 EGC38782.1 - 4.3e-24 83.3 11.7 9e-08 31.5 0.1 6.6 6 0 0 6 6 6 5 Kelch motif MmgE_PrpD PF03972.9 EGC38783.1 - 2.3e-138 461.1 0.0 2.8e-138 460.8 0.0 1.0 1 0 0 1 1 1 1 MmgE/PrpD family DDE_3 PF13358.1 EGC38784.1 - 5.2e-05 23.0 0.0 7e-05 22.6 0.0 1.2 1 0 0 1 1 1 1 DDE superfamily endonuclease RasGAP PF00616.14 EGC38784.1 - 0.044 13.4 0.1 0.049 13.3 0.1 1.1 1 0 0 1 1 1 0 GTPase-activator protein for Ras-like GTPase SnoaL_2 PF12680.2 EGC38785.1 - 8.9e-26 90.2 10.5 0.00096 19.5 0.0 5.5 6 0 0 6 6 6 5 SnoaL-like domain HopJ PF08888.6 EGC38785.1 - 3.7e-11 43.0 5.3 0.79 9.7 0.0 5.5 5 0 0 5 5 5 5 HopJ type III effector protein GCHY-1 PF02649.9 EGC38785.1 - 9.7e-05 21.7 3.6 3.6 6.7 0.1 4.9 5 0 0 5 5 5 2 Type I GTP cyclohydrolase folE2 Imm26 PF15572.1 EGC38785.1 - 0.00073 19.6 1.3 1.3e+02 2.7 0.0 5.5 5 0 0 5 5 5 0 Immunity protein 26 DpnD-PcfM PF14207.1 EGC38785.1 - 0.3 10.8 11.4 73 3.2 0.1 6.3 5 0 0 5 5 5 0 DpnD/PcfM-like protein Mg296 PF09644.5 EGC38785.1 - 2.5 7.9 24.0 4.2 7.2 0.3 5.2 5 0 0 5 5 5 0 Mg296 protein WD40 PF00400.27 EGC38786.1 - 2.4e-31 106.4 11.4 2.3e-08 33.5 0.0 7.5 7 0 0 7 7 7 7 WD domain, G-beta repeat zf-C3HC4_2 PF13923.1 EGC38786.1 - 5.7e-08 32.6 7.0 5.7e-08 32.6 4.8 2.2 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38786.1 - 5.4e-07 29.1 7.6 1.7e-06 27.6 5.2 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC38786.1 - 9.6e-07 28.5 5.9 9.6e-07 28.5 4.1 2.1 2 0 0 2 2 2 1 Ring finger domain zf-RING_5 PF14634.1 EGC38786.1 - 7.5e-06 25.5 6.9 7.5e-06 25.5 4.8 2.1 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC38786.1 - 4.6e-05 23.0 4.2 4.6e-05 23.0 2.9 2.2 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EGC38786.1 - 5.7e-05 23.0 0.0 0.00023 21.0 0.0 2.1 1 0 0 1 1 1 1 U-box domain zf-C3HC4_4 PF15227.1 EGC38786.1 - 7.1e-05 22.5 5.4 0.00028 20.7 3.7 2.1 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC38786.1 - 0.0023 17.9 5.3 0.0023 17.9 3.7 2.6 3 0 0 3 3 2 1 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC38786.1 - 0.017 14.8 2.5 0.059 13.0 1.7 1.9 1 0 0 1 1 1 0 RING-type zinc-finger zf-P11 PF03854.9 EGC38786.1 - 0.029 13.8 4.3 0.033 13.6 1.1 2.3 2 0 0 2 2 2 0 P-11 zinc finger zf-RING_4 PF14570.1 EGC38786.1 - 0.31 10.6 4.9 0.81 9.3 3.4 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-C4H2 PF10146.4 EGC38786.1 - 1.8 8.5 11.8 0.11 12.4 2.3 2.2 2 0 0 2 2 2 0 Zinc finger-containing protein DUF2775 PF10950.3 EGC38786.1 - 5.3 7.3 10.1 2.9 8.1 3.9 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2775) WD40 PF00400.27 EGC38787.1 - 4.5e-57 188.0 37.3 3.8e-08 32.8 0.4 13.3 13 0 0 13 13 13 12 WD domain, G-beta repeat NrfD_2 PF14589.1 EGC38787.1 - 0.34 10.5 0.0 0.54 9.8 0.0 1.2 1 0 0 1 1 1 0 Polysulfide reductase AAA_21 PF13304.1 EGC38789.1 - 4.4e-15 56.4 3.9 4.4e-15 56.4 2.7 2.7 3 0 0 3 3 3 1 AAA domain DUF948 PF06103.6 EGC38789.1 - 0.2 11.5 2.0 0.33 10.8 0.2 2.4 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) IncA PF04156.9 EGC38789.1 - 0.3 10.6 0.0 0.3 10.6 0.0 2.8 3 0 0 3 3 3 0 IncA protein COG4 PF08318.7 EGC38790.1 - 5.3e-09 35.2 10.3 5.3e-09 35.2 7.1 4.3 4 2 1 5 5 5 1 COG4 transport protein Herpes_LMP2 PF07415.6 EGC38790.1 - 4.9 5.6 5.6 9.6 4.6 3.9 1.4 1 0 0 1 1 1 0 Gammaherpesvirus latent membrane protein (LMP2) protein PsbP PF01789.11 EGC38791.1 - 2.2e-05 23.9 4.9 0.13 11.6 0.0 3.7 4 0 0 4 4 4 3 PsbP SNF2_N PF00176.18 EGC38792.1 - 2.3e-67 226.8 1.1 2.3e-67 226.8 0.7 2.0 2 0 0 2 2 2 1 SNF2 family N-terminal domain Rad60-SLD PF11976.3 EGC38792.1 - 7.5e-25 86.4 3.6 3.3e-08 33.1 0.0 6.3 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Helicase_C PF00271.26 EGC38792.1 - 5.8e-15 54.9 0.0 2.3e-14 52.9 0.0 2.2 1 0 0 1 1 1 1 Helicase conserved C-terminal domain Chromo PF00385.19 EGC38792.1 - 3.9e-14 52.0 2.1 1.8e-09 37.1 0.2 3.0 2 0 0 2 2 2 2 Chromo (CHRromatin Organisation MOdifier) domain Lipase_3 PF01764.20 EGC38793.1 - 3.1e-13 49.5 0.0 8.4e-13 48.1 0.0 1.7 2 0 0 2 2 2 1 Lipase (class 3) DUF2974 PF11187.3 EGC38793.1 - 0.00078 18.8 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF2974) Abhydrolase_6 PF12697.2 EGC38793.1 - 0.021 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC38793.1 - 0.089 12.3 0.0 0.18 11.3 0.0 1.4 1 0 0 1 1 1 0 alpha/beta hydrolase fold SET_assoc PF11767.3 EGC38793.1 - 1.4 8.3 6.0 2.8 7.3 0.5 3.2 2 1 1 3 3 3 0 Histone lysine methyltransferase SET associated Ras PF00071.17 EGC38794.1 - 1.8e-60 203.0 0.0 2.1e-60 202.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38794.1 - 1.9e-19 70.2 0.0 3.1e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38794.1 - 8.7e-09 34.8 0.0 1e-08 34.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC38794.1 - 1.5e-07 30.9 0.0 1.2e-06 28.1 0.0 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC38794.1 - 0.00021 21.2 0.0 0.00035 20.5 0.0 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC38794.1 - 0.0045 16.2 0.1 0.028 13.7 0.1 2.2 1 1 0 1 1 1 1 Ferrous iron transport protein B ATP_bind_1 PF03029.12 EGC38794.1 - 0.015 14.8 1.1 0.16 11.5 0.0 2.0 1 1 1 2 2 2 0 Conserved hypothetical ATP binding protein Septin PF00735.13 EGC38794.1 - 0.023 13.6 0.1 0.059 12.3 0.0 1.7 2 0 0 2 2 2 0 Septin DUF258 PF03193.11 EGC38794.1 - 0.055 12.6 0.0 0.081 12.1 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_25 PF13481.1 EGC38794.1 - 0.068 12.5 0.0 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain LRAT PF04970.8 EGC38796.1 - 0.0012 18.7 1.0 0.0012 18.7 0.7 2.2 2 0 0 2 2 2 1 Lecithin retinol acyltransferase DPBB_1 PF03330.13 EGC38797.1 - 0.0096 15.9 0.2 0.031 14.2 0.1 1.9 1 1 0 1 1 1 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Potex_coat PF06184.6 EGC38797.1 - 0.078 12.3 0.0 13 5.1 0.0 2.3 2 0 0 2 2 2 0 Potexvirus coat protein Aminotran_5 PF00266.14 EGC38798.1 - 1.1e-05 24.4 0.0 1.4e-05 24.0 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Chromo PF00385.19 EGC38799.1 - 3.7e-15 55.3 1.5 4e-15 55.2 1.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC38799.1 - 0.13 12.0 0.3 0.19 11.4 0.2 1.4 1 1 0 1 1 1 0 RNA binding activity-knot of a chromodomain Peptidase_M17 PF00883.16 EGC38800.1 - 3.8e-116 387.3 0.1 4.9e-116 386.9 0.1 1.1 1 0 0 1 1 1 1 Cytosol aminopeptidase family, catalytic domain Peptidase_M17_N PF02789.12 EGC38800.1 - 5e-24 84.4 0.1 1e-23 83.4 0.1 1.5 1 0 0 1 1 1 1 Cytosol aminopeptidase family, N-terminal domain Perilipin PF03036.11 EGC38801.1 - 1.6e-05 23.9 1.9 0.0063 15.3 0.0 3.3 2 2 2 4 4 4 2 Perilipin family Holin_LLH PF09682.5 EGC38801.1 - 0.024 14.7 0.7 0.079 13.0 0.5 2.0 1 0 0 1 1 1 0 Phage holin protein (Holin_LLH) Unstab_antitox PF09720.5 EGC38801.1 - 0.044 13.4 0.1 0.12 12.1 0.1 1.7 1 0 0 1 1 1 0 Putative addiction module component Tape_meas_lam_C PF09718.5 EGC38801.1 - 0.046 13.6 0.9 2.1 8.3 0.0 3.3 4 0 0 4 4 4 0 Lambda phage tail tape-measure protein (Tape_meas_lam_C) YtxH PF12732.2 EGC38801.1 - 2.5 8.5 6.0 9.8 6.6 1.3 2.9 2 1 0 2 2 2 0 YtxH-like protein Ndc1_Nup PF09531.5 EGC38801.1 - 2.7 6.3 10.4 3.9 5.7 7.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup DUF3791 PF12668.2 EGC38802.1 - 0.037 13.6 0.1 0.11 12.1 0.0 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3791) DUF365 PF04033.7 EGC38802.1 - 0.31 11.0 4.5 0.17 11.8 0.9 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF365) DUF2013 PF09431.5 EGC38803.1 - 6.7e-16 58.3 0.6 6.7e-16 58.3 0.4 3.5 1 1 2 3 3 3 1 Protein of unknown function (DUF2013) Glycos_trans_3N PF02885.12 EGC38803.1 - 0.047 13.2 0.2 0.11 12.1 0.1 1.6 1 0 0 1 1 1 0 Glycosyl transferase family, helical bundle domain TIG PF01833.19 EGC38804.1 - 3.6e-29 100.5 60.8 1.1e-09 38.1 2.7 8.3 6 2 2 8 8 8 7 IPT/TIG domain DUF4469 PF14734.1 EGC38804.1 - 0.1 12.4 0.0 0.1 12.4 0.0 4.5 6 1 1 7 7 7 0 Domain of unknown function (DUF4469) with IG-like fold Choline_transpo PF04515.7 EGC38805.1 - 2.2e-83 279.7 34.3 6.2e-83 278.2 20.9 2.3 2 1 0 2 2 2 2 Plasma-membrane choline transporter Yip1 PF04893.12 EGC38805.1 - 1.8 8.0 39.0 0.97 8.9 0.9 4.6 3 1 0 4 4 4 0 Yip1 domain Sec1 PF00995.18 EGC38806.1 - 3.6e-137 458.3 9.3 4.4e-137 458.1 6.5 1.1 1 0 0 1 1 1 1 Sec1 family GlutR_dimer PF00745.15 EGC38806.1 - 0.058 13.3 0.0 0.38 10.7 0.0 2.4 3 0 0 3 3 3 0 Glutamyl-tRNAGlu reductase, dimerisation domain MFS_1 PF07690.11 EGC38807.1 - 0.0025 16.5 50.0 0.14 10.8 9.3 3.5 1 1 0 2 2 2 2 Major Facilitator Superfamily PS_Dcarbxylase PF02666.10 EGC38808.1 - 0.023 13.9 8.8 0.9 8.7 0.0 4.1 4 0 0 4 4 4 0 Phosphatidylserine decarboxylase DUF1109 PF06532.6 EGC38808.1 - 0.03 13.7 4.1 0.11 11.9 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF1109) Shisa PF13908.1 EGC38808.1 - 0.89 9.7 12.7 0.62 10.2 0.6 4.6 1 1 4 5 5 5 0 Wnt and FGF inhibitory regulator DUF898 PF05987.8 EGC38808.1 - 2.6 6.8 9.7 0.26 10.1 0.4 2.6 1 1 0 2 2 2 0 Bacterial protein of unknown function (DUF898) Cyto_ox_2 PF02322.10 EGC38808.1 - 2.6 7.1 25.4 0.17 11.0 1.4 3.4 1 1 3 4 4 4 0 Cytochrome oxidase subunit II Plant_vir_prot PF01307.12 EGC38808.1 - 8.2 6.2 33.2 16 5.2 0.2 7.4 2 2 3 7 7 7 0 Plant viral movement protein zf-RING_2 PF13639.1 EGC38809.1 - 7.1e-10 38.5 12.2 8.5e-10 38.3 7.6 1.8 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC38809.1 - 1.6e-06 28.1 6.0 4.4e-06 26.7 4.2 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC38809.1 - 1.6e-06 27.6 9.3 1.6e-06 27.6 6.4 1.6 1 1 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38809.1 - 2.3e-06 27.1 14.0 5.2e-06 26.0 9.7 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38809.1 - 6.7e-06 26.0 15.3 7.2e-06 25.9 9.2 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) TFIIA PF03153.8 EGC38809.1 - 6.5e-05 23.0 19.7 9.2e-05 22.5 13.7 1.1 1 0 0 1 1 1 1 Transcription factor IIA, alpha/beta subunit zf-RING_5 PF14634.1 EGC38809.1 - 0.0017 18.0 12.5 0.0036 17.0 8.7 1.6 1 0 0 1 1 1 1 zinc-RING finger domain Asp-B-Hydro_N PF05279.6 EGC38809.1 - 0.047 13.5 27.1 0.0096 15.7 13.1 2.2 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region ATP-synt_8 PF00895.15 EGC38809.1 - 0.06 13.5 0.6 0.06 13.5 0.4 2.4 3 0 0 3 3 2 0 ATP synthase protein 8 zf-Apc11 PF12861.2 EGC38809.1 - 0.087 12.6 5.5 0.26 11.1 3.8 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC38809.1 - 0.12 12.3 12.8 0.35 10.7 8.9 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING Nicastrin PF05450.10 EGC38810.1 - 4.3e-34 117.7 0.3 8.2e-34 116.8 0.2 1.4 1 0 0 1 1 1 1 Nicastrin Peptidase_M28 PF04389.12 EGC38810.1 - 9.2e-08 32.0 0.0 1.3e-07 31.5 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 GCS PF03074.11 EGC38811.1 - 1.4e-157 524.5 3.1 1.8e-157 524.1 2.2 1.2 1 0 0 1 1 1 1 Glutamate-cysteine ligase DUF1199 PF06712.6 EGC38811.1 - 0.11 12.3 1.2 0.38 10.5 0.8 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1199) Ded_cyto PF06920.8 EGC38812.1 - 3.1e-45 153.6 2.0 7.9e-45 152.3 0.4 2.4 2 0 0 2 2 2 1 Dedicator of cytokinesis DOCK-C2 PF14429.1 EGC38812.1 - 7.7e-37 126.7 1.1 7.7e-37 126.7 0.8 2.5 2 0 0 2 2 2 1 C2 domain in Dock180 and Zizimin proteins SH3_1 PF00018.23 EGC38812.1 - 1.3e-09 37.2 0.0 2.8e-09 36.1 0.0 1.6 1 0 0 1 1 1 1 SH3 domain SH3_9 PF14604.1 EGC38812.1 - 1.1e-08 34.5 0.0 2.1e-08 33.5 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_2 PF07653.12 EGC38812.1 - 0.00029 20.2 0.0 0.00062 19.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Pentapeptide PF00805.17 EGC38813.1 - 1.7e-25 87.7 25.9 4.7e-11 41.6 2.4 4.8 2 2 3 5 5 5 5 Pentapeptide repeats (8 copies) Pentapeptide_4 PF13599.1 EGC38813.1 - 5.3e-20 71.0 32.7 2.8e-11 43.0 7.5 3.4 3 0 0 3 3 3 2 Pentapeptide repeats (9 copies) Pentapeptide_3 PF13576.1 EGC38813.1 - 1.9e-14 53.2 38.8 4.3e-08 32.9 5.2 5.1 3 2 2 5 5 5 4 Pentapeptide repeats (9 copies) BTB_2 PF02214.17 EGC38813.1 - 4.1e-14 52.5 0.0 1.2e-13 51.0 0.0 1.8 1 0 0 1 1 1 1 BTB/POZ domain AlaDh_PNT_C PF01262.16 EGC38813.1 - 3.6 7.1 4.5 11 5.5 3.1 1.8 1 1 0 1 1 1 0 Alanine dehydrogenase/PNT, C-terminal domain Pribosyltran PF00156.22 EGC38814.1 - 3.2e-27 94.7 0.0 4.4e-27 94.2 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGC38814.1 - 3e-07 29.8 0.2 2.9e-06 26.6 0.1 2.0 1 1 0 1 1 1 1 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EGC38814.1 - 9.1e-07 28.3 0.0 1.3e-06 27.8 0.0 1.3 1 0 0 1 1 1 1 Phosphoribosyl transferase Aconitase_2_N PF06434.8 EGC38814.1 - 0.056 12.8 0.1 0.096 12.0 0.0 1.4 1 0 0 1 1 1 0 Aconitate hydratase 2 N-terminus Mur_ligase_C PF02875.16 EGC38814.1 - 0.076 13.0 0.0 0.21 11.6 0.0 1.8 1 1 0 1 1 1 0 Mur ligase family, glutamate ligase domain PAP2 PF01569.16 EGC38815.1 - 7.7e-21 74.1 3.6 7.7e-21 74.1 2.5 1.6 2 0 0 2 2 2 1 PAP2 superfamily Bax1-I PF01027.15 EGC38815.1 - 0.11 12.0 12.3 1.1 8.7 8.6 2.0 1 1 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 DUF2955 PF11168.3 EGC38815.1 - 8.1 6.1 9.8 2.7 7.6 0.8 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2955) Yae1_N PF09811.4 EGC38816.1 - 5.4e-10 38.6 0.4 7.9e-10 38.1 0.3 1.3 1 0 0 1 1 1 1 Essential protein Yae1, N terminal Nse5 PF08691.5 EGC38816.1 - 0.002 16.7 0.6 0.0031 16.0 0.4 1.2 1 0 0 1 1 1 1 DNA repair proteins Nse5 and Nse6 HTH_41 PF14502.1 EGC38817.1 - 0.079 12.5 0.0 0.16 11.6 0.0 1.5 1 0 0 1 1 1 0 Helix-turn-helix domain PCI PF01399.22 EGC38818.1 - 6.6e-14 52.1 3.1 7.2e-14 51.9 0.7 2.1 2 1 0 2 2 2 1 PCI domain DUF1843 PF08898.5 EGC38818.1 - 0.21 11.6 1.6 0.44 10.6 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1843) DUF2250 PF10007.4 EGC38818.1 - 0.24 11.3 1.7 5.5 6.9 0.1 3.0 2 1 0 2 2 2 0 Uncharacterized protein conserved in archaea (DUF2250) RRM_6 PF14259.1 EGC38819.1 - 0.00016 21.5 0.1 0.00048 20.0 0.0 1.9 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC38819.1 - 0.0015 18.1 0.4 0.0041 16.7 0.1 1.9 2 0 0 2 2 2 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC38820.1 - 1e-14 53.8 0.0 1.7e-14 53.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38820.1 - 2.6e-09 36.9 0.0 4.6e-09 36.1 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38820.1 - 3.7e-07 29.8 0.0 7.2e-07 28.9 0.0 1.5 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_3 PF08777.6 EGC38820.1 - 0.007 16.1 0.0 0.014 15.2 0.0 1.5 1 0 0 1 1 1 1 RNA binding motif DUF4651 PF15513.1 EGC38820.1 - 0.018 14.4 0.1 0.034 13.5 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4651) Srg PF02118.16 EGC38821.1 - 0.0014 18.1 2.7 0.0014 18.1 1.9 1.7 2 0 0 2 2 2 1 Srg family chemoreceptor SUR7 PF06687.7 EGC38821.1 - 0.0018 17.8 8.0 0.0018 17.8 5.5 2.4 2 1 0 2 2 2 1 SUR7/PalI family COX1 PF00115.15 EGC38821.1 - 0.0024 16.5 2.5 0.0024 16.5 1.7 1.5 2 0 0 2 2 2 1 Cytochrome C and Quinol oxidase polypeptide I DUF4064 PF13273.1 EGC38821.1 - 0.066 13.3 7.7 0.11 12.6 2.5 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF202 PF02656.10 EGC38821.1 - 0.19 11.9 6.8 0.21 11.8 0.1 2.7 2 1 0 2 2 2 0 Domain of unknown function (DUF202) DUF3139 PF11337.3 EGC38821.1 - 1.3 9.3 4.9 6.6 7.0 0.0 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3139) Mem_trans PF03547.13 EGC38821.1 - 1.6 6.9 8.1 0.85 7.8 1.0 2.3 2 0 0 2 2 2 0 Membrane transport protein ABC2_membrane_5 PF13346.1 EGC38821.1 - 1.8 7.8 13.8 0.055 12.7 1.1 2.9 3 0 0 3 3 3 0 ABC-2 family transporter protein DUF4293 PF14126.1 EGC38821.1 - 2.9 7.7 9.1 3.2 7.6 4.1 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF4293) PGG PF13962.1 EGC38821.1 - 3.2 7.3 8.6 9 5.9 3.4 2.4 2 1 0 2 2 2 0 Domain of unknown function Claudin_2 PF13903.1 EGC38821.1 - 3.4 7.3 9.3 0.3 10.7 0.9 2.3 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3816 PF12822.2 EGC38821.1 - 5.9 6.7 15.9 78 3.1 11.0 2.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3816) FKBP_C PF00254.23 EGC38822.1 - 7.6e-29 99.5 0.0 9.2e-29 99.3 0.0 1.0 1 0 0 1 1 1 1 FKBP-type peptidyl-prolyl cis-trans isomerase RRM_1 PF00076.17 EGC38823.1 - 1.1e-48 162.7 1.6 4e-21 74.4 0.0 3.5 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38823.1 - 2e-32 110.9 0.1 2e-14 53.2 0.0 3.2 3 0 0 3 3 3 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC38823.1 - 8.2e-25 86.4 2.9 1.4e-10 40.8 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) C1_2 PF03107.11 EGC38823.1 - 0.013 15.5 0.8 0.023 14.7 0.6 1.4 1 0 0 1 1 1 0 C1 domain Nup35_RRM_2 PF14605.1 EGC38823.1 - 0.055 13.2 0.1 5.3 6.8 0.0 3.0 3 0 0 3 3 3 0 Nup53/35/40-type RNA recognition motif Linker_histone PF00538.14 EGC38824.1 - 3.9e-24 84.5 0.1 7.1e-24 83.7 0.1 1.4 1 0 0 1 1 1 1 linker histone H1 and H5 family PaaX PF07848.7 EGC38824.1 - 0.012 15.6 0.0 0.02 14.8 0.0 1.4 1 0 0 1 1 1 0 PaaX-like protein Mucin PF01456.12 EGC38824.1 - 4 7.2 17.6 3.1 7.5 0.7 2.1 2 0 0 2 2 2 0 Mucin-like glycoprotein FAD_binding_6 PF00970.19 EGC38825.1 - 4.4e-31 106.9 0.0 7.4e-31 106.2 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase FAD-binding domain NAD_binding_1 PF00175.16 EGC38825.1 - 2.6e-30 105.1 0.0 4.5e-30 104.4 0.0 1.4 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain NAD_binding_6 PF08030.7 EGC38825.1 - 6.5e-07 29.3 0.2 0.00024 21.0 0.0 2.4 3 0 0 3 3 3 2 Ferric reductase NAD binding domain FAD_binding_9 PF08021.6 EGC38825.1 - 0.0067 16.3 0.0 0.012 15.5 0.0 1.4 1 0 0 1 1 1 1 Siderophore-interacting FAD-binding domain SURF6 PF04935.7 EGC38826.1 - 1.4e-24 86.5 50.0 1.4e-24 86.5 34.6 2.2 1 1 1 2 2 2 1 Surfeit locus protein 6 DUF3439 PF11921.3 EGC38826.1 - 0.0022 17.7 7.5 0.0063 16.2 5.2 1.7 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC38826.1 - 0.17 11.6 12.2 0.33 10.7 8.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Glyco_hydro_18 PF00704.23 EGC38828.1 - 3.4e-13 49.7 5.5 6.8e-13 48.7 3.8 1.6 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 OppC_N PF12911.2 EGC38828.1 - 0.095 12.0 0.0 0.26 10.6 0.0 1.8 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C Baculo_VP91_N PF08475.5 EGC38828.1 - 0.1 11.9 1.7 5.1 6.4 1.2 2.7 1 1 0 1 1 1 0 Viral capsid protein 91 N-terminal DDE_Tnp_1_7 PF13843.1 EGC38829.1 - 1.5e-05 24.2 0.3 4.7e-05 22.6 0.1 1.9 2 1 0 2 2 2 1 Transposase IS4 LRR_8 PF13855.1 EGC38831.1 - 0.11 12.2 0.2 0.94 9.2 0.0 2.5 2 1 1 3 3 3 0 Leucine rich repeat LRR_4 PF12799.2 EGC38831.1 - 0.26 10.9 1.7 18 5.1 0.1 3.2 1 1 2 3 3 3 0 Leucine Rich repeats (2 copies) Vma12 PF11712.3 EGC38832.1 - 9e-22 77.3 0.2 9e-22 77.3 0.2 2.8 2 2 1 3 3 3 1 Endoplasmic reticulum-based factor for assembly of V-ATPase DUF2992 PF11208.3 EGC38832.1 - 0.00013 21.8 0.1 0.00013 21.8 0.1 3.3 3 1 1 4 4 4 1 Protein of unknown function (DUF2992) Sugar_tr PF00083.19 EGC38832.1 - 0.00029 19.5 0.1 0.00053 18.6 0.1 1.4 1 0 0 1 1 1 1 Sugar (and other) transporter MFS_2 PF13347.1 EGC38832.1 - 0.00033 19.1 0.0 0.00046 18.7 0.0 1.1 1 0 0 1 1 1 1 MFS/sugar transport protein Mem_trans PF03547.13 EGC38832.1 - 0.0017 16.7 1.7 0.0021 16.4 1.2 1.2 1 0 0 1 1 1 1 Membrane transport protein DUF4519 PF15012.1 EGC38832.1 - 1.1 9.2 0.0 1.1 9.2 0.0 3.0 3 1 0 3 3 3 0 Domain of unknown function (DUF4519) BRCT PF00533.21 EGC38833.1 - 9.4e-08 32.1 0.5 3.8e-06 26.9 0.1 3.3 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain CAF-1_p150 PF11600.3 EGC38833.1 - 0.00016 21.1 30.8 0.00016 21.1 21.4 3.4 3 0 0 3 3 3 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal RRM_5 PF13893.1 EGC38833.1 - 0.00039 20.2 0.3 0.0011 18.7 0.2 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38833.1 - 0.017 15.0 0.7 0.12 12.3 0.1 2.6 3 0 0 3 3 3 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC38833.1 - 0.023 14.3 0.3 0.092 12.3 0.2 2.1 1 0 0 1 1 1 0 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF1477 PF07346.6 EGC38833.1 - 0.043 13.8 1.5 0.22 11.5 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF1477) Gluconate_2-dh3 PF13618.1 EGC38833.1 - 2.4 8.3 9.3 0.83 9.8 0.6 3.1 3 0 0 3 3 3 0 Gluconate 2-dehydrogenase subunit 3 FNIP PF05725.7 EGC38834.1 - 3.5e-30 103.6 10.9 3e-14 52.6 0.2 3.0 2 1 1 3 3 3 3 FNIP Repeat LRR_1 PF00560.28 EGC38834.1 - 0.026 14.5 1.5 4.5 7.6 0.1 3.3 2 1 1 3 3 3 0 Leucine Rich Repeat LRR_6 PF13516.1 EGC38834.1 - 0.032 14.2 5.6 4.1 7.7 0.3 3.7 4 0 0 4 4 4 0 Leucine Rich repeat ShlB PF03865.8 EGC38834.1 - 0.032 12.9 0.0 0.048 12.4 0.0 1.3 1 1 0 1 1 1 0 Haemolysin secretion/activation protein ShlB/FhaC/HecB Cys_rich_VLP PF14194.1 EGC38834.1 - 0.043 13.5 0.0 3.4 7.4 0.0 2.5 1 1 1 2 2 2 0 Cysteine-rich VLP LRR_7 PF13504.1 EGC38834.1 - 0.074 13.2 1.4 6.5 7.4 0.0 3.6 4 1 0 4 4 4 0 Leucine rich repeat Keratin_matx PF04579.7 EGC38834.1 - 0.29 11.4 2.3 0.36 11.1 1.6 1.2 1 0 0 1 1 1 0 Keratin, high-sulphur matrix protein zf-RVT PF13966.1 EGC38835.1 - 1.9e-06 28.0 0.9 4.2e-06 26.9 0.6 1.6 1 0 0 1 1 1 1 zinc-binding in reverse transcriptase GATA PF00320.22 EGC38835.1 - 0.0012 18.0 0.0 0.0031 16.8 0.0 1.7 1 0 0 1 1 1 1 GATA zinc finger Myb_DNA-binding PF00249.26 EGC38836.1 - 2.2e-50 168.4 22.4 8.5e-16 57.7 0.0 6.4 6 0 0 6 6 6 4 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC38836.1 - 4.3e-47 158.0 21.6 9.7e-14 51.2 0.3 7.4 2 1 4 6 6 6 5 Myb-like DNA-binding domain APC_CDC26 PF10471.4 EGC38836.1 - 0.037 14.7 0.3 0.037 14.7 0.2 4.6 5 0 0 5 5 5 0 Anaphase-promoting complex APC subunit 1 DUF3439 PF11921.3 EGC38836.1 - 0.089 12.5 8.1 0.19 11.4 5.6 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Myb_DNA-bind_4 PF13837.1 EGC38836.1 - 3.7 7.7 34.5 0.07 13.2 2.0 7.2 5 3 1 6 6 6 0 Myb/SANT-like DNA-binding domain adh_short PF00106.20 EGC38837.1 - 4.3e-24 85.2 0.0 5.3e-24 84.9 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC38837.1 - 3.5e-15 56.4 0.0 4.2e-15 56.1 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase Epimerase PF01370.16 EGC38837.1 - 8.6e-07 28.6 0.1 1.6e-06 27.7 0.0 1.6 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family DUF1776 PF08643.5 EGC38837.1 - 2.6e-06 26.7 0.0 5e-06 25.8 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) KR PF08659.5 EGC38837.1 - 1.2e-05 25.0 0.0 2e-05 24.3 0.0 1.3 1 1 0 1 1 1 1 KR domain NAD_binding_10 PF13460.1 EGC38837.1 - 0.0015 18.5 0.0 0.0022 18.0 0.0 1.3 1 0 0 1 1 1 1 NADH(P)-binding RmlD_sub_bind PF04321.12 EGC38837.1 - 0.018 13.9 0.0 0.032 13.1 0.0 1.4 1 0 0 1 1 1 0 RmlD substrate binding domain Pkinase_Tyr PF07714.12 EGC38838.1 - 1.4e-21 76.7 0.0 1.7e-21 76.4 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC38838.1 - 1.3e-15 57.3 0.0 1.7e-15 56.9 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain PGI PF00342.14 EGC38839.1 - 5.3e-222 737.5 0.4 6.1e-222 737.3 0.3 1.0 1 0 0 1 1 1 1 Phosphoglucose isomerase Phasin_2 PF09361.5 EGC38839.1 - 0.021 14.8 0.1 0.15 12.1 0.0 2.2 2 0 0 2 2 2 0 Phasin protein DUF4473 PF14747.1 EGC38839.1 - 0.099 12.8 0.1 0.3 11.3 0.1 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4473) GCC2_GCC3 PF07699.8 EGC38840.1 - 0.017 14.7 0.5 0.072 12.6 0.4 2.2 1 0 0 1 1 1 0 GCC2 and GCC3 EI24 PF07264.6 EGC38840.1 - 0.029 13.8 1.1 0.24 10.8 0.1 2.4 3 0 0 3 3 3 0 Etoposide-induced protein 2.4 (EI24) His_Phos_2 PF00328.17 EGC38841.1 - 2.6e-34 119.1 0.0 3.2e-34 118.8 0.0 1.1 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 2) His_Phos_1 PF00300.17 EGC38841.1 - 0.037 14.1 0.0 0.085 12.9 0.0 1.7 1 1 0 1 1 1 0 Histidine phosphatase superfamily (branch 1) Rifin_STEVOR PF02009.11 EGC38842.1 - 8.5e-06 25.6 0.4 1.4e-05 24.8 0.3 1.4 1 0 0 1 1 1 1 Rifin/stevor family V-SNARE_C PF12352.3 EGC38842.1 - 0.0002 21.3 2.3 0.00039 20.4 0.6 2.1 2 0 0 2 2 2 1 Snare region anchored in the vesicle membrane C-terminus V-SNARE PF05008.10 EGC38842.1 - 0.00024 21.2 2.9 0.00024 21.2 2.0 3.3 2 2 1 3 3 2 1 Vesicle transport v-SNARE protein N-terminus ABC2_membrane_3 PF12698.2 EGC38842.1 - 0.0015 17.6 0.1 0.0018 17.3 0.1 1.2 1 0 0 1 1 1 1 ABC-2 family transporter protein DUF3533 PF12051.3 EGC38842.1 - 0.012 14.4 0.8 0.016 13.9 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3533) Amnionless PF14828.1 EGC38842.1 - 0.046 12.2 0.7 0.061 11.8 0.5 1.2 1 0 0 1 1 1 0 Amnionless Pex24p PF06398.6 EGC38842.1 - 0.051 12.3 0.0 0.057 12.2 0.0 1.2 1 0 0 1 1 1 0 Integral peroxisomal membrane peroxin MtrF PF09472.5 EGC38842.1 - 0.059 12.6 1.7 0.11 11.6 1.2 1.4 1 0 0 1 1 1 0 Tetrahydromethanopterin S-methyltransferase, F subunit (MtrF) Sec20 PF03908.8 EGC38842.1 - 0.093 12.4 5.4 0.081 12.6 2.0 2.2 2 1 0 2 2 2 0 Sec20 Streptin-Immun PF11083.3 EGC38842.1 - 0.17 11.8 9.8 1.6 8.8 2.8 3.0 3 0 0 3 3 3 0 Lantibiotic streptin immunity protein 60KD_IMP PF02096.15 EGC38842.1 - 0.24 11.0 3.2 0.21 11.2 1.2 1.6 1 1 0 1 1 1 0 60Kd inner membrane protein SNARE PF05739.14 EGC38842.1 - 0.26 11.0 9.7 0.029 14.0 2.8 2.5 2 1 0 2 2 2 0 SNARE domain DUF2207 PF09972.4 EGC38842.1 - 0.37 9.3 7.0 0.15 10.6 0.8 2.1 1 1 0 2 2 2 0 Predicted membrane protein (DUF2207) ORF6C PF10552.4 EGC38842.1 - 0.54 10.0 11.0 3 7.5 0.6 3.8 2 1 2 4 4 4 0 ORF6C domain Hormone_1 PF00103.15 EGC38842.1 - 0.6 9.4 5.9 4.5 6.5 1.8 2.4 2 0 0 2 2 2 0 Somatotropin hormone family DUF1664 PF07889.7 EGC38842.1 - 0.68 9.7 10.9 1.3 8.8 0.1 2.6 2 1 0 2 2 2 0 Protein of unknown function (DUF1664) DUF2116 PF09889.4 EGC38842.1 - 0.73 9.6 3.2 2.5 7.9 2.2 1.9 1 0 0 1 1 1 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) DUF912 PF06024.7 EGC38842.1 - 0.74 9.8 9.9 0.033 14.2 1.5 2.2 1 1 1 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF1759 PF03564.10 EGC38842.1 - 1.3 8.7 5.8 0.72 9.6 0.1 2.5 2 1 0 2 2 2 0 Protein of unknown function (DUF1759) Synaptobrevin PF00957.16 EGC38842.1 - 2 8.0 16.4 0.021 14.4 4.3 2.6 3 0 0 3 3 3 0 Synaptobrevin DUF2390 PF09523.5 EGC38842.1 - 4.8 7.4 8.1 4.8 7.4 0.4 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF2390) EzrA PF06160.7 EGC38842.1 - 5 5.1 23.6 2 6.4 8.7 3.2 2 1 0 2 2 2 0 Septation ring formation regulator, EzrA Nup54 PF13874.1 EGC38842.1 - 6.1 6.5 19.8 0.33 10.6 1.7 3.2 2 2 1 3 3 3 0 Nucleoporin complex subunit 54 HAMP PF00672.20 EGC38842.1 - 6.9 6.9 6.1 6.8 6.9 2.1 2.4 2 0 0 2 2 2 0 HAMP domain Uds1 PF15456.1 EGC38842.1 - 9.1 6.2 13.4 8.6 6.3 0.8 2.2 2 0 0 2 2 2 0 Up-regulated During Septation CsbD PF05532.7 EGC38843.1 - 4.6e-05 23.0 2.3 8.9e-05 22.0 1.3 1.7 2 0 0 2 2 2 1 CsbD-like Apc1 PF12859.2 EGC38844.1 - 3e-17 62.7 0.1 1.1e-15 57.6 0.0 3.2 2 0 0 2 2 2 1 Anaphase-promoting complex subunit 1 PC_rep PF01851.17 EGC38844.1 - 9.2e-05 22.4 10.8 0.47 10.8 0.0 5.7 6 0 0 6 6 6 3 Proteasome/cyclosome repeat LSM PF01423.17 EGC38845.1 - 2.2e-18 65.5 0.9 3e-18 65.1 0.6 1.2 1 0 0 1 1 1 1 LSM domain Leu_zip PF15294.1 EGC38845.1 - 0.023 13.8 0.2 0.026 13.6 0.1 1.1 1 0 0 1 1 1 0 Leucine zipper DUF3914 PF13053.1 EGC38847.1 - 0.35 11.0 11.8 0.43 10.7 8.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3914) SR-25 PF10500.4 EGC38847.1 - 0.83 9.0 18.7 0.91 8.9 12.9 1.0 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein CBFB_NFYA PF02045.10 EGC38847.1 - 1.8 9.1 6.8 2.3 8.8 4.7 1.2 1 0 0 1 1 1 0 CCAAT-binding transcription factor (CBF-B/NF-YA) subunit B Vfa1 PF08432.5 EGC38847.1 - 4.9 7.1 18.5 4.8 7.1 12.9 1.1 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 DUF2956 PF11169.3 EGC38847.1 - 5.7 6.9 15.9 6.1 6.8 11.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2956) Rrp15p PF07890.7 EGC38847.1 - 6 6.9 18.1 6.2 6.8 12.5 1.0 1 0 0 1 1 1 0 Rrp15p eIF3_subunit PF08597.5 EGC38847.1 - 6.5 6.2 22.8 7.4 6.0 15.8 1.0 1 0 0 1 1 1 0 Translation initiation factor eIF3 subunit FNIP PF05725.7 EGC38848.1 - 9.7e-15 54.2 7.6 1.4e-08 34.5 0.5 9.4 7 3 3 10 10 10 7 FNIP Repeat Spc7 PF08317.6 EGC38848.1 - 0.012 14.2 0.5 0.024 13.2 0.3 1.4 1 0 0 1 1 1 0 Spc7 kinetochore protein ERM PF00769.14 EGC38849.1 - 0.019 14.5 13.7 0.01 15.3 2.4 2.2 2 0 0 2 2 2 0 Ezrin/radixin/moesin family DUF2400 PF09674.5 EGC38849.1 - 0.19 11.3 11.7 0.26 10.9 0.2 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2400) CorA PF01544.13 EGC38849.1 - 0.25 10.3 11.2 0.15 11.0 1.9 2.5 1 1 0 2 2 2 0 CorA-like Mg2+ transporter protein DUF4200 PF13863.1 EGC38849.1 - 0.32 10.9 0.0 0.32 10.9 0.0 4.0 1 1 2 3 3 3 0 Domain of unknown function (DUF4200) IZUMO PF15005.1 EGC38849.1 - 0.52 10.3 8.2 0.05 13.6 0.7 2.3 2 1 0 2 2 2 0 Izumo sperm-egg fusion Cortex-I_coil PF09304.5 EGC38849.1 - 0.64 10.0 14.2 0.31 11.1 0.6 2.7 2 1 0 2 2 2 0 Cortexillin I, coiled coil Laminin_II PF06009.7 EGC38849.1 - 0.67 9.7 7.0 0.82 9.4 0.1 3.0 2 2 1 3 3 3 0 Laminin Domain II CENP-F_leu_zip PF10473.4 EGC38849.1 - 4.1 7.2 22.0 0.35 10.7 4.4 3.2 2 2 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Seryl_tRNA_N PF02403.17 EGC38849.1 - 9 6.3 18.0 1 9.4 0.6 3.4 1 1 3 4 4 4 0 Seryl-tRNA synthetase N-terminal domain Pkinase_Tyr PF07714.12 EGC38851.1 - 3.4e-59 200.0 0.6 2.1e-58 197.4 0.0 2.1 2 0 0 2 2 2 1 Protein tyrosine kinase Pkinase PF00069.20 EGC38851.1 - 1e-54 185.4 2.3 1.1e-54 185.3 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain SH2 PF00017.19 EGC38851.1 - 1.2e-05 24.9 0.0 3.5e-05 23.5 0.0 1.8 1 0 0 1 1 1 1 SH2 domain Cbl_N2 PF02761.9 EGC38851.1 - 0.002 18.1 0.3 0.0053 16.7 0.2 1.7 1 0 0 1 1 1 1 CBL proto-oncogene N-terminus, EF hand-like domain Peptidase_M16_C PF05193.16 EGC38852.1 - 9.3e-18 64.5 0.0 4.2e-15 55.9 0.0 3.2 3 0 0 3 3 3 2 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC38852.1 - 7.7e-08 32.2 0.2 3.4e-07 30.1 0.0 2.1 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) SF3a60_bindingd PF12108.3 EGC38852.1 - 0.015 14.7 1.6 6 6.4 0.1 3.2 2 0 0 2 2 2 0 Splicing factor SF3a60 binding domain DUF788 PF05620.6 EGC38853.1 - 0.014 15.2 1.5 0.02 14.7 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF788) DUF3896 PF13035.1 EGC38853.1 - 0.036 14.1 1.6 0.1 12.6 1.1 1.8 1 0 0 1 1 1 0 Protein of unknown function (DUF3896) Ribosomal_S15 PF00312.17 EGC38853.1 - 0.88 9.3 5.2 3.4 7.4 0.1 2.6 2 1 1 3 3 3 0 Ribosomal protein S15 UPF0118 PF01594.11 EGC38854.1 - 0.36 9.7 6.9 0.032 13.2 1.2 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF20 HTH_36 PF13730.1 EGC38855.1 - 0.012 15.7 0.1 0.8 9.8 0.0 2.2 2 0 0 2 2 2 0 Helix-turn-helix domain Zn_peptidase_2 PF04298.7 EGC38855.1 - 0.036 13.4 0.1 0.056 12.7 0.0 1.2 1 0 0 1 1 1 0 Putative neutral zinc metallopeptidase CarbpepA_inh PF02977.10 EGC38855.1 - 3.1 7.4 5.2 21 4.7 0.1 2.2 2 0 0 2 2 2 0 Carboxypeptidase A inhibitor FNIP PF05725.7 EGC38856.1 - 1.8e-151 491.9 57.4 8.7e-18 64.0 0.6 13.0 5 3 2 13 13 13 12 FNIP Repeat MerC PF03203.9 EGC38856.1 - 5.4e-06 26.7 0.1 17 5.8 0.0 6.1 3 2 1 7 7 7 1 MerC mercury resistance protein DUF4495 PF14906.1 EGC38856.1 - 0.0017 17.3 0.1 1.4e+02 1.2 0.0 6.8 7 3 2 9 9 9 0 Domain of unknown function (DUF4495) Shigella_OspC PF06128.6 EGC38856.1 - 0.13 11.7 4.6 12 5.2 0.0 4.4 5 0 0 5 5 5 0 Shigella flexneri OspC protein Lactamase_B_2 PF12706.2 EGC38857.1 - 6.9e-37 126.8 0.6 9.2e-37 126.4 0.4 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B_3 PF13483.1 EGC38857.1 - 4.6e-15 55.6 0.0 6.2e-15 55.2 0.0 1.2 1 0 0 1 1 1 1 Beta-lactamase superfamily domain Lactamase_B PF00753.22 EGC38857.1 - 0.00044 19.9 0.2 0.0012 18.4 0.0 1.8 2 0 0 2 2 2 1 Metallo-beta-lactamase superfamily Glyco_transf_43 PF03360.11 EGC38857.1 - 0.0063 16.0 0.0 0.01 15.4 0.0 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 43 TFIIB PF00382.14 EGC38858.1 - 1.9e-41 139.7 0.1 6.4e-24 83.5 0.0 2.5 2 0 0 2 2 2 2 Transcription factor TFIIB repeat TF_Zn_Ribbon PF08271.7 EGC38858.1 - 1.4e-11 43.5 2.5 2.4e-11 42.7 1.7 1.3 1 0 0 1 1 1 1 TFIIB zinc-binding Cyclin_C PF02984.14 EGC38858.1 - 0.00036 20.4 5.4 0.11 12.4 0.2 3.1 2 1 1 3 3 3 2 Cyclin, C-terminal domain Sigma70_r4 PF04545.11 EGC38858.1 - 0.0013 18.0 0.0 0.33 10.2 0.0 2.5 2 0 0 2 2 2 1 Sigma-70, region 4 Sigma70_r4_2 PF08281.7 EGC38858.1 - 0.0028 17.0 0.0 0.097 12.1 0.0 2.4 2 0 0 2 2 2 1 Sigma-70, region 4 Yippee-Mis18 PF03226.9 EGC38858.1 - 0.0092 16.0 0.8 2.8 8.0 0.2 2.7 2 0 0 2 2 2 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly HTH_Tnp_ISL3 PF13542.1 EGC38858.1 - 0.011 14.9 0.0 2.4 7.3 0.0 3.0 2 0 0 2 2 2 0 Helix-turn-helix domain of transposase family ISL3 HTH_3 PF01381.17 EGC38858.1 - 0.014 15.2 0.1 1.6 8.6 0.0 2.4 2 0 0 2 2 2 0 Helix-turn-helix Rrf2 PF02082.15 EGC38858.1 - 0.018 15.1 0.1 2.1 8.4 0.0 2.5 2 0 0 2 2 2 0 Transcriptional regulator HTH_11 PF08279.7 EGC38858.1 - 0.03 13.9 0.0 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 HTH domain HTH_Crp_2 PF13545.1 EGC38858.1 - 0.05 13.4 0.0 2.2 8.1 0.0 2.7 2 0 0 2 2 2 0 Crp-like helix-turn-helix domain GntR PF00392.16 EGC38858.1 - 0.068 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Bacterial regulatory proteins, gntR family HTH_23 PF13384.1 EGC38858.1 - 0.073 12.7 0.0 0.54 9.9 0.0 2.3 2 0 0 2 2 2 0 Homeodomain-like domain ETF_alpha PF00766.14 EGC38859.1 - 2.8e-39 132.6 0.7 6.2e-39 131.5 0.5 1.6 1 0 0 1 1 1 1 Electron transfer flavoprotein FAD-binding domain ETF PF01012.16 EGC38859.1 - 6.9e-36 123.4 0.3 1e-35 122.8 0.2 1.3 1 0 0 1 1 1 1 Electron transfer flavoprotein domain FNIP PF05725.7 EGC38860.1 - 9.3e-155 502.4 74.3 1.3e-16 60.2 0.5 9.6 1 1 9 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.8 EGC38860.1 - 7.9e-05 22.5 0.1 25 4.8 0.0 6.4 3 2 4 7 7 7 1 Phage minor tail protein Metallophos PF00149.23 EGC38861.1 - 5.7e-38 130.3 1.0 9.6e-38 129.5 0.7 1.4 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase PPP5 PF08321.7 EGC38861.1 - 1.7e-24 85.6 0.5 3.5e-24 84.6 0.3 1.5 1 0 0 1 1 1 1 PPP5 TPR repeat region TPR_11 PF13414.1 EGC38861.1 - 2.3e-17 62.3 10.8 3.4e-12 45.8 1.2 2.4 2 0 0 2 2 2 2 TPR repeat TPR_2 PF07719.12 EGC38861.1 - 8e-13 47.2 9.1 1.6e-06 27.5 0.8 4.3 3 1 1 4 4 4 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC38861.1 - 7.3e-10 38.0 15.3 3.5e-05 23.2 0.9 4.3 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38861.1 - 7.3e-08 32.6 2.7 2.9e-05 24.3 0.2 3.0 2 1 1 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38861.1 - 1.9e-07 31.5 2.0 0.0064 17.1 0.2 2.4 1 1 2 3 3 3 3 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38861.1 - 3.8e-06 26.9 4.9 0.00083 19.6 0.1 2.7 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38861.1 - 8.3e-06 25.2 8.7 0.00012 21.6 0.7 3.0 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_12 PF13424.1 EGC38861.1 - 2.5e-05 24.1 6.0 0.0007 19.4 0.5 2.6 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC38861.1 - 0.00021 21.6 0.0 0.0074 16.8 0.0 2.7 2 0 0 2 2 2 1 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC38861.1 - 0.00025 20.8 0.4 0.00063 19.5 0.3 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_17 PF13431.1 EGC38861.1 - 0.00094 19.1 4.8 0.0071 16.4 0.3 2.9 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC38861.1 - 0.0025 17.4 1.8 0.14 11.9 0.1 2.5 2 0 0 2 2 2 1 Tetratricopeptide repeat MIT PF04212.13 EGC38861.1 - 0.012 15.4 2.4 0.29 11.0 0.3 2.4 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain Metallophos_2 PF12850.2 EGC38861.1 - 0.037 13.8 0.0 0.057 13.2 0.0 1.3 1 0 0 1 1 1 0 Calcineurin-like phosphoesterase superfamily domain TPR_9 PF13371.1 EGC38861.1 - 0.18 11.6 0.0 0.37 10.6 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat BTAD PF03704.12 EGC38861.1 - 0.19 12.0 0.0 0.33 11.2 0.0 1.3 1 0 0 1 1 1 0 Bacterial transcriptional activator domain Apc3 PF12895.2 EGC38861.1 - 0.22 11.6 8.0 1.3 9.1 4.9 2.5 1 1 1 2 2 2 0 Anaphase-promoting complex, cyclosome, subunit 3 FNIP PF05725.7 EGC38862.1 - 2.6e-68 225.7 44.4 2.6e-16 59.2 0.5 6.6 2 1 1 6 6 6 6 FNIP Repeat DUF1769 PF08588.5 EGC38862.1 - 0.39 10.6 23.2 1.6 8.7 0.1 7.7 3 2 7 10 10 10 0 Protein of unknown function (DUF1769) Profilin PF00235.14 EGC38863.1 - 4.9e-10 39.5 0.3 5.5e-10 39.4 0.2 1.2 1 0 0 1 1 1 1 Profilin G-alpha PF00503.15 EGC38864.1 - 2e-107 359.2 10.6 2.4e-107 359.0 7.3 1.0 1 0 0 1 1 1 1 G-protein alpha subunit Arf PF00025.16 EGC38864.1 - 7.1e-14 51.4 2.0 3e-10 39.6 0.1 2.6 2 1 0 2 2 2 2 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC38864.1 - 9.9e-05 21.5 1.0 0.016 14.3 0.1 2.5 2 1 0 2 2 2 2 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC38864.1 - 0.0062 17.0 0.1 6.6 7.2 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein MMR_HSR1 PF01926.18 EGC38864.1 - 0.0084 16.0 0.1 0.63 10.0 0.0 2.8 2 1 0 2 2 2 1 50S ribosome-binding GTPase AAA_29 PF13555.1 EGC38864.1 - 0.011 15.1 0.1 0.028 13.9 0.1 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain SRPRB PF09439.5 EGC38864.1 - 0.023 13.9 1.4 0.62 9.2 0.0 2.9 3 1 0 3 3 3 0 Signal recognition particle receptor beta subunit FtsK_SpoIIIE PF01580.13 EGC38864.1 - 0.13 11.7 0.0 0.29 10.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family COPI_assoc PF08507.5 EGC38865.1 - 3.5e-23 81.8 7.4 4.8e-23 81.3 5.1 1.1 1 0 0 1 1 1 1 COPI associated protein Tetraspannin PF00335.15 EGC38865.1 - 1.1 8.5 0.0 1.1 8.5 0.0 2.7 2 1 1 3 3 3 0 Tetraspanin family VWA_2 PF13519.1 EGC38866.1 - 6.2e-11 42.7 0.0 1.3e-10 41.6 0.0 1.6 1 0 0 1 1 1 1 von Willebrand factor type A domain MMR_HSR1 PF01926.18 EGC38867.1 - 3.4e-18 65.6 0.3 2.3e-13 50.1 0.0 4.1 3 1 1 4 4 4 2 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC38867.1 - 1.4e-08 34.1 0.1 3.6e-05 23.0 0.1 2.8 2 0 0 2 2 2 2 Ferrous iron transport protein B DUF258 PF03193.11 EGC38867.1 - 2.6e-05 23.4 1.4 3.6e-05 22.9 0.0 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC38867.1 - 0.0044 17.4 5.9 0.02 15.4 0.0 3.8 4 0 0 4 4 4 1 Miro-like protein Dynamin_N PF00350.18 EGC38867.1 - 0.0096 15.7 0.6 0.0096 15.7 0.4 5.6 5 3 2 7 7 7 1 Dynamin family NOG1 PF06858.9 EGC38867.1 - 0.045 13.6 0.0 0.13 12.1 0.0 1.9 1 0 0 1 1 1 0 Nucleolar GTP-binding protein 1 (NOG1) Mucin PF01456.12 EGC38867.1 - 0.33 10.7 7.7 0.55 9.9 5.3 1.3 1 0 0 1 1 1 0 Mucin-like glycoprotein AT_hook PF02178.14 EGC38868.1 - 0.032 13.8 46.6 1.2 9.0 2.2 4.5 4 0 0 4 4 4 0 AT hook motif ABC2_membrane_3 PF12698.2 EGC38868.1 - 6.9 5.5 11.1 1.3 7.9 0.2 2.2 2 0 0 2 2 2 0 ABC-2 family transporter protein APG9 PF04109.11 EGC38869.1 - 3e-108 362.0 5.6 4e-108 361.6 3.9 1.2 1 0 0 1 1 1 1 Autophagy protein Apg9 Apc15p PF05841.6 EGC38869.1 - 0.069 13.8 7.4 0.14 12.8 5.1 1.5 1 0 0 1 1 1 0 Apc15p protein Ald_Xan_dh_C2 PF02738.13 EGC38870.1 - 5.7e-189 628.9 0.1 7.6e-189 628.5 0.1 1.1 1 0 0 1 1 1 1 Molybdopterin-binding domain of aldehyde dehydrogenase FAD_binding_5 PF00941.16 EGC38870.1 - 1e-47 161.7 0.2 2.5e-47 160.4 0.0 1.7 2 0 0 2 2 2 1 FAD binding domain in molybdopterin dehydrogenase CO_deh_flav_C PF03450.12 EGC38870.1 - 6.4e-34 115.9 0.0 8.7e-33 112.3 0.0 2.4 2 0 0 2 2 2 1 CO dehydrogenase flavoprotein C-terminal domain Ald_Xan_dh_C PF01315.17 EGC38870.1 - 2.7e-31 107.9 0.1 6.2e-31 106.7 0.1 1.7 1 0 0 1 1 1 1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain Fer2_2 PF01799.15 EGC38870.1 - 1e-27 95.7 0.0 2.2e-27 94.7 0.0 1.6 1 0 0 1 1 1 1 [2Fe-2S] binding domain Fer2 PF00111.22 EGC38870.1 - 3.2e-07 30.0 0.4 1e-06 28.4 0.1 2.1 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Imm46 PF15585.1 EGC38872.1 - 0.12 12.4 4.7 0.048 13.7 1.9 1.4 1 1 0 1 1 1 0 Immunity protein 46 PPP4R2 PF09184.6 EGC38872.1 - 1.5 8.3 21.7 1.8 8.0 15.1 1.1 1 0 0 1 1 1 0 PPP4R2 YebO PF13974.1 EGC38872.1 - 4.8 7.0 9.4 9.8 6.0 2.9 2.4 1 1 1 2 2 2 0 YebO-like protein CDC45 PF02724.9 EGC38872.1 - 5.9 4.7 14.9 6.2 4.7 10.3 1.0 1 0 0 1 1 1 0 CDC45-like protein Rep_1 PF01446.12 EGC38872.1 - 7.4 5.8 14.2 8.4 5.6 9.8 1.0 1 0 0 1 1 1 0 Replication protein Kri1 PF05178.7 EGC38872.1 - 7.9 6.8 22.8 7.8 6.8 13.7 2.4 1 1 1 2 2 2 0 KRI1-like family DUF4484 PF14831.1 EGC38872.1 - 8.1 6.5 11.2 9.8 6.2 7.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4484) Peptidase_C1 PF00112.18 EGC38873.1 - 5.4e-70 235.6 2.6 8.9e-70 234.9 1.8 1.3 1 0 0 1 1 1 1 Papain family cysteine protease Inhibitor_I29 PF08246.7 EGC38873.1 - 2.8e-13 49.9 2.9 4.5e-13 49.2 2.0 1.3 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC38873.1 - 2.7e-05 22.8 0.1 0.0098 14.4 0.0 2.2 2 0 0 2 2 2 2 Peptidase C1-like family Ibs_toxin PF13956.1 EGC38873.1 - 0.48 10.2 2.1 1.1 9.1 1.5 1.6 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system MtaB PF12176.3 EGC38874.1 - 0.063 11.7 0.0 0.084 11.2 0.0 1.1 1 0 0 1 1 1 0 Methanol-cobalamin methyltransferase B subunit PI3_PI4_kinase PF00454.22 EGC38875.1 - 2.1e-36 125.5 0.7 2.1e-36 125.5 0.5 2.4 2 1 0 2 2 2 1 Phosphatidylinositol 3- and 4-kinase PI3Ka PF00613.15 EGC38875.1 - 2.9e-28 98.2 0.1 9.4e-28 96.6 0.1 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PH PF00169.24 EGC38875.1 - 1.7e-12 47.4 0.3 1.7e-12 47.4 0.2 3.0 2 0 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC38875.1 - 0.004 17.4 0.1 0.004 17.4 0.0 3.2 2 0 0 2 2 2 1 Pleckstrin homology domain Kinesin PF00225.18 EGC38876.1 - 5.1e-111 370.5 0.1 5.1e-111 370.5 0.1 3.3 3 0 0 3 3 3 1 Kinesin motor domain PH PF00169.24 EGC38876.1 - 1.2e-12 47.8 1.8 1.2e-12 47.8 1.3 3.2 3 0 0 3 3 3 1 PH domain DUF3694 PF12473.3 EGC38876.1 - 9.6e-07 28.5 2.9 6.3e-05 22.6 0.0 4.0 3 1 0 3 3 3 1 Kinesin protein KIF1B PF12423.3 EGC38876.1 - 0.00011 22.1 0.2 0.00071 19.5 0.1 2.6 1 0 0 1 1 1 1 Kinesin protein 1B PH_8 PF15409.1 EGC38876.1 - 0.00093 19.2 0.2 0.0035 17.3 0.1 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain Epimerase PF01370.16 EGC38877.1 - 1.2e-06 28.2 0.0 0.02 14.3 0.0 2.2 2 0 0 2 2 2 2 NAD dependent epimerase/dehydratase family UDPG_MGDP_dh_N PF03721.9 EGC38877.1 - 0.0002 20.8 0.4 0.00041 19.7 0.3 1.5 1 0 0 1 1 1 1 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain NAD_binding_2 PF03446.10 EGC38877.1 - 0.0023 17.8 0.0 0.0037 17.1 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase TrkA_N PF02254.13 EGC38877.1 - 0.012 15.6 0.0 0.03 14.3 0.1 1.8 2 0 0 2 2 2 0 TrkA-N domain Pyr_redox PF00070.22 EGC38877.1 - 0.014 15.7 0.4 0.064 13.6 0.0 2.2 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 2-Hacid_dh_C PF02826.14 EGC38877.1 - 0.018 14.2 0.1 0.029 13.5 0.1 1.3 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGC38877.1 - 0.06 13.3 0.0 0.083 12.8 0.0 1.2 1 0 0 1 1 1 0 NADH(P)-binding Shikimate_DH PF01488.15 EGC38877.1 - 0.068 13.2 0.4 0.19 11.8 0.1 1.8 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase zf-C3HC4_3 PF13920.1 EGC38878.1 - 1.4e-08 34.2 7.9 2.3e-08 33.5 5.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC38878.1 - 4.3e-08 32.6 9.6 1.2e-07 31.2 6.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC38878.1 - 2.6e-07 30.3 9.1 4.4e-07 29.6 6.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC38878.1 - 1.6e-05 24.8 9.7 2.9e-05 24.0 6.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC38878.1 - 4.2e-05 23.5 6.6 0.0001 22.3 4.6 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC38878.1 - 0.00056 19.5 9.2 0.0011 18.6 6.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC38878.1 - 0.028 14.3 8.6 0.1 12.5 6.0 2.0 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC38878.1 - 0.62 9.9 5.7 1.8 8.4 3.9 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EGC38878.1 - 0.79 9.5 7.6 5.1 6.9 5.3 2.2 1 1 0 1 1 1 0 Double zinc ribbon zf-RING_4 PF14570.1 EGC38878.1 - 0.88 9.2 11.1 6.6 6.3 7.7 2.3 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain TPR_11 PF13414.1 EGC38879.1 - 3.3e-19 68.3 1.4 2.4e-08 33.4 0.0 4.7 3 1 2 5 5 5 4 TPR repeat TPR_12 PF13424.1 EGC38879.1 - 2.3e-15 56.3 1.4 0.0003 20.6 0.0 5.1 4 1 1 5 5 5 4 Tetratricopeptide repeat TPR_1 PF00515.23 EGC38879.1 - 1.2e-13 50.0 5.8 0.016 14.7 0.1 6.7 8 0 0 8 8 7 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC38879.1 - 2.6e-11 42.5 3.4 0.0028 17.4 0.4 6.4 7 0 0 7 7 7 2 Tetratricopeptide repeat TPR_17 PF13431.1 EGC38879.1 - 1.8e-10 40.1 0.4 0.013 15.6 0.0 5.9 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC38879.1 - 7.7e-09 34.7 8.7 0.11 12.3 0.0 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat TPR_19 PF14559.1 EGC38879.1 - 7.1e-08 32.6 0.4 0.0039 17.5 0.0 3.6 2 1 2 4 4 4 3 Tetratricopeptide repeat TPR_16 PF13432.1 EGC38879.1 - 2e-07 31.4 0.0 0.0092 16.6 0.0 2.6 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_14 PF13428.1 EGC38879.1 - 2e-06 27.9 0.0 3.2 8.6 0.0 5.3 3 3 4 7 7 6 2 Tetratricopeptide repeat TPR_6 PF13174.1 EGC38879.1 - 6.7e-05 23.0 0.6 0.014 15.7 0.0 3.8 4 0 0 4 4 3 1 Tetratricopeptide repeat Apc3 PF12895.2 EGC38879.1 - 0.00045 20.3 0.1 0.028 14.5 0.0 3.7 2 1 2 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_7 PF13176.1 EGC38879.1 - 0.0063 16.2 1.8 46 4.1 0.0 5.2 5 0 0 5 5 5 0 Tetratricopeptide repeat MAS20 PF02064.10 EGC38879.1 - 0.007 16.2 0.6 0.65 9.9 0.5 2.5 1 1 1 2 2 2 1 MAS20 protein import receptor TPR_9 PF13371.1 EGC38879.1 - 0.0089 15.8 0.0 1.4 8.8 0.0 2.7 2 1 0 2 2 2 1 Tetratricopeptide repeat SNAP PF14938.1 EGC38879.1 - 0.014 14.5 5.6 0.023 13.8 1.7 2.4 2 0 0 2 2 2 0 Soluble NSF attachment protein, SNAP MIT PF04212.13 EGC38879.1 - 0.018 14.9 1.1 9.9 6.1 0.0 3.8 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain CENP-B_dimeris PF09026.5 EGC38879.1 - 0.97 9.7 18.4 0.035 14.3 2.8 2.5 2 0 0 2 2 2 0 Centromere protein B dimerisation domain zinc_ribbon_2 PF13240.1 EGC38880.1 - 0.061 12.8 0.7 0.061 12.8 0.5 2.4 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGC38880.1 - 0.14 11.4 1.9 0.21 10.8 0.3 2.1 2 0 0 2 2 2 0 zinc-ribbon domain WD40 PF00400.27 EGC38881.1 - 2.9e-49 163.2 21.2 2.9e-08 33.2 0.1 7.6 7 0 0 7 7 7 7 WD domain, G-beta repeat PFU PF09070.6 EGC38881.1 - 2.2e-37 127.6 3.2 5e-37 126.4 2.2 1.7 1 0 0 1 1 1 1 PFU (PLAA family ubiquitin binding) PUL PF08324.6 EGC38881.1 - 1.8e-35 122.0 10.1 3e-35 121.3 7.0 1.4 1 0 0 1 1 1 1 PUL domain BBS2_Mid PF14783.1 EGC38881.1 - 0.00061 19.5 0.0 0.39 10.4 0.0 3.8 3 0 0 3 3 3 1 Ciliary BBSome complex subunit 2, middle region Coiled PF05710.7 EGC38882.1 - 6e-05 23.4 4.5 8e-05 23.0 3.1 1.3 1 1 0 1 1 1 1 Coiled coil Kinesin PF00225.18 EGC38883.1 - 1.8e-106 355.6 2.6 1.8e-106 355.6 1.8 1.9 2 0 0 2 2 2 1 Kinesin motor domain ATG16 PF08614.6 EGC38883.1 - 0.29 10.9 37.8 1.3 8.7 9.9 3.3 2 1 1 3 3 3 0 Autophagy protein 16 (ATG16) Ank_2 PF12796.2 EGC38884.1 - 1.3e-12 47.8 0.0 4.4e-10 39.7 0.0 3.2 2 1 1 3 3 3 2 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC38884.1 - 1.7e-10 41.1 0.0 1.5e-05 25.3 0.0 3.4 3 0 0 3 3 3 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC38884.1 - 1.7e-08 33.8 0.0 0.0023 17.6 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat F-box-like PF12937.2 EGC38884.1 - 3.8e-08 32.9 0.2 9.4e-08 31.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like Ank_5 PF13857.1 EGC38884.1 - 2e-07 31.0 0.0 0.0092 16.2 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeats (many copies) F-box PF00646.28 EGC38884.1 - 3.6e-05 23.3 0.4 0.00013 21.5 0.3 2.1 1 0 0 1 1 1 1 F-box domain Ank_3 PF13606.1 EGC38884.1 - 6.2e-05 22.8 0.0 0.11 12.7 0.0 3.5 2 0 0 2 2 2 2 Ankyrin repeat Swi5 PF07061.6 EGC38884.1 - 0.043 13.6 0.3 0.043 13.6 0.2 3.6 3 0 0 3 3 3 0 Swi5 DUF3727 PF12527.3 EGC38885.1 - 0.12 12.4 0.0 0.15 12.2 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3727) AAA_18 PF13238.1 EGC38886.1 - 3.8e-08 33.6 3.3 4.1e-08 33.5 0.4 2.1 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC38886.1 - 1.7e-06 28.8 2.9 2e-05 25.4 0.1 2.4 1 1 1 2 2 2 1 AAA domain Cytidylate_kin2 PF13189.1 EGC38886.1 - 8.7e-06 25.7 4.0 0.065 13.1 0.3 2.7 2 1 0 2 2 2 2 Cytidylate kinase-like family AAA_16 PF13191.1 EGC38886.1 - 0.0051 16.8 0.1 0.03 14.2 0.0 2.0 2 0 0 2 2 2 1 AAA ATPase domain AAA_28 PF13521.1 EGC38886.1 - 0.029 14.3 0.1 0.08 12.9 0.0 1.8 2 0 0 2 2 2 0 AAA domain Got1 PF04178.7 EGC38887.1 - 8e-26 90.4 21.9 9.3e-26 90.2 15.2 1.1 1 0 0 1 1 1 1 Got1/Sft2-like family SdpI PF13630.1 EGC38887.1 - 0.044 13.4 19.2 0.063 12.9 1.4 2.2 2 0 0 2 2 2 0 SdpI/YhfL protein family DUF1700 PF08006.6 EGC38887.1 - 0.46 9.7 12.4 0.66 9.2 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1700) DUF3487 PF11990.3 EGC38887.1 - 7.6 5.9 10.4 0.7 9.3 0.2 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF3487) DUF3430 PF11912.3 EGC38888.1 - 1.2e-13 51.3 29.8 1.4e-13 51.2 20.6 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) KH_1 PF00013.24 EGC38889.1 - 9e-28 95.7 5.4 4.8e-16 58.1 1.2 2.4 2 0 0 2 2 2 2 KH domain KH_3 PF13014.1 EGC38889.1 - 1.4e-19 69.2 2.6 9.3e-10 37.9 0.3 2.7 2 0 0 2 2 2 2 KH domain Ank_2 PF12796.2 EGC38889.1 - 2.3e-15 56.7 0.4 7.8e-15 54.9 0.0 2.0 2 0 0 2 2 2 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC38889.1 - 3.2e-14 51.9 0.2 5.8e-06 25.8 0.0 3.0 3 0 0 3 3 2 2 Ankyrin repeat Ank_5 PF13857.1 EGC38889.1 - 9e-13 48.0 1.6 4.6e-08 33.0 0.0 3.1 3 1 0 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC38889.1 - 8.2e-11 42.1 2.8 5.3e-07 29.9 0.0 4.2 4 1 1 5 5 5 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC38889.1 - 1.2e-08 34.3 0.0 0.0014 18.6 0.0 4.0 3 1 0 3 3 3 2 Ankyrin repeat KH_4 PF13083.1 EGC38889.1 - 1.9e-05 24.2 1.0 0.3 10.7 0.0 3.1 2 1 0 2 2 2 2 KH domain SLS PF14611.1 EGC38889.1 - 2.5e-05 23.8 2.7 0.011 15.1 0.1 2.4 1 1 1 2 2 2 2 Mitochondrial inner-membrane-bound regulator KH_2 PF07650.12 EGC38889.1 - 4.2e-05 23.0 3.1 0.028 13.9 0.4 2.7 2 0 0 2 2 2 2 KH domain Host_attach PF10116.4 EGC38889.1 - 0.057 13.6 0.0 0.11 12.7 0.0 1.4 1 0 0 1 1 1 0 Protein required for attachment to host cells TPR_8 PF13181.1 EGC38889.1 - 0.17 11.7 4.2 0.14 12.0 0.5 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat Fe_hyd_lg_C PF02906.9 EGC38890.1 - 2.6e-90 302.5 0.0 4.1e-90 301.9 0.0 1.3 1 0 0 1 1 1 1 Iron only hydrogenase large subunit, C-terminal domain Fe_hyd_SSU PF02256.12 EGC38890.1 - 2.5e-11 43.3 0.3 6.6e-11 42.0 0.2 1.7 1 0 0 1 1 1 1 Iron hydrogenase small subunit FAD_syn PF06574.7 EGC38890.1 - 0.0032 17.0 0.2 0.0069 16.0 0.1 1.5 1 0 0 1 1 1 1 FAD synthetase Cation_efflux PF01545.16 EGC38891.1 - 1.4e-69 234.3 4.4 1.4e-69 234.3 3.1 2.7 3 1 0 3 3 3 1 Cation efflux family DUF1686 PF07937.6 EGC38891.1 - 0.052 13.1 1.3 0.062 12.9 0.1 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF1686) DAD PF02109.11 EGC38893.1 - 6.7e-44 148.5 6.3 7.7e-44 148.3 4.3 1.0 1 0 0 1 1 1 1 DAD family Bax1-I PF01027.15 EGC38893.1 - 0.014 15.0 3.0 0.015 14.8 2.1 1.2 1 0 0 1 1 1 0 Inhibitor of apoptosis-promoting Bax1 Diphthamide_syn PF01866.12 EGC38893.1 - 0.35 10.0 1.6 0.7 9.0 0.9 1.5 1 1 1 2 2 2 0 Putative diphthamide synthesis protein ParA PF10609.4 EGC38894.1 - 3.1e-36 123.0 0.5 9.2e-36 121.5 0.1 1.9 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EGC38894.1 - 4.1e-13 49.1 0.0 7e-13 48.4 0.0 1.3 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGC38894.1 - 1.2e-09 38.3 0.0 5.1e-08 32.9 0.0 2.2 2 0 0 2 2 2 1 AAA domain MipZ PF09140.6 EGC38894.1 - 9.7e-06 24.8 0.0 1.7e-05 24.0 0.0 1.5 1 1 0 1 1 1 1 ATPase MipZ Fer4_NifH PF00142.13 EGC38894.1 - 1.4e-05 24.3 0.1 0.024 13.8 0.0 2.5 2 0 0 2 2 2 2 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family ArsA_ATPase PF02374.10 EGC38894.1 - 0.00085 18.4 0.2 0.019 14.0 0.0 2.6 2 1 1 3 3 3 1 Anion-transporting ATPase VirC1 PF07015.6 EGC38894.1 - 0.0049 15.9 0.0 0.0087 15.1 0.0 1.3 1 0 0 1 1 1 1 VirC1 protein Vault PF01505.13 EGC38895.1 - 9.6e-65 214.4 0.3 5.9e-14 51.8 0.0 5.7 5 0 0 5 5 5 5 Major Vault Protein repeat MVP_shoulder PF11978.3 EGC38895.1 - 7.4e-48 161.3 0.0 1.6e-47 160.2 0.0 1.6 1 0 0 1 1 1 1 Shoulder domain Phosphorylase PF00343.15 EGC38896.1 - 0 1183.2 1.7 0 1183.0 1.2 1.0 1 0 0 1 1 1 1 Carbohydrate phosphorylase Nucleoporin_C PF03177.9 EGC38897.1 - 6.1e-67 226.4 13.4 6.1e-67 226.4 9.3 2.9 3 1 0 3 3 3 1 Non-repetitive/WGA-negative nucleoporin C-terminal Nucleoporin_N PF08801.6 EGC38897.1 - 5.6e-40 137.3 8.8 5.6e-40 137.3 6.1 1.8 2 0 0 2 2 2 1 Nup133 N terminal like Acetyltransf_7 PF13508.1 EGC38898.1 - 8.6e-09 35.4 0.2 1.5e-08 34.6 0.1 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC38898.1 - 4e-07 29.9 0.0 6.2e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_9 PF13527.1 EGC38898.1 - 0.00011 22.0 0.0 0.0011 18.8 0.0 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC38898.1 - 0.0012 18.6 0.0 0.0022 17.8 0.0 1.4 1 0 0 1 1 1 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGC38898.1 - 0.0039 16.9 0.0 0.0067 16.1 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_4 PF13420.1 EGC38898.1 - 0.023 14.6 0.1 0.04 13.8 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Nipped-B_C PF12830.2 EGC38898.1 - 0.038 13.6 0.0 0.078 12.6 0.0 1.4 1 0 0 1 1 1 0 Sister chromatid cohesion C-terminus DUF229 PF02995.12 EGC38898.1 - 0.087 11.2 0.8 0.15 10.4 0.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF229) DUF3430 PF11912.3 EGC38899.1 - 4.1e-11 43.1 30.2 5.3e-11 42.7 20.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) DUF3586 PF12131.3 EGC38899.1 - 0.55 10.3 13.5 0.17 11.9 0.7 3.3 3 1 0 3 3 3 0 Protein of unknown function (DUF3586) Ibs_toxin PF13956.1 EGC38899.1 - 2.1 8.2 5.0 3.4 7.5 3.5 1.3 1 0 0 1 1 1 0 Toxin Ibs, type I toxin-antitoxin system zf-B_box PF00643.19 EGC38901.1 - 0.0002 21.2 8.8 0.00039 20.2 6.1 1.5 1 0 0 1 1 1 1 B-box zinc finger DUF3584 PF12128.3 EGC38901.1 - 0.003 14.9 3.4 0.0037 14.6 2.3 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3584) V-SNARE PF05008.10 EGC38901.1 - 0.027 14.6 4.8 0.83 9.8 0.4 2.6 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus DUF1539 PF07560.6 EGC38901.1 - 0.039 13.8 9.7 0.12 12.2 6.7 2.0 1 1 0 1 1 1 0 Domain of Unknown Function (DUF1539) YlbD_coat PF14071.1 EGC38901.1 - 0.091 12.8 12.1 0.1 12.6 7.1 2.1 1 1 1 2 2 2 0 Putative coat protein Ribosomal_L30 PF00327.15 EGC38901.1 - 0.11 12.1 2.0 0.43 10.2 0.1 2.7 3 0 0 3 3 3 0 Ribosomal protein L30p/L7e MCPsignal PF00015.16 EGC38901.1 - 0.15 11.5 0.6 0.21 11.1 0.0 1.5 2 0 0 2 2 2 0 Methyl-accepting chemotaxis protein (MCP) signalling domain Telomere_reg-2 PF10193.4 EGC38901.1 - 0.62 10.3 8.8 2.2 8.5 1.1 2.4 1 1 1 2 2 2 0 Telomere length regulation protein Snapin_Pallidin PF14712.1 EGC38901.1 - 0.67 10.3 7.3 8.9 6.6 1.5 2.5 2 0 0 2 2 2 0 Snapin/Pallidin MCM_N PF14551.1 EGC38901.1 - 3 8.3 9.8 0.47 10.9 0.7 2.4 2 0 0 2 2 2 0 MCM N-terminal domain FlaC_arch PF05377.6 EGC38901.1 - 5.6 6.9 14.0 2.7 7.9 0.7 3.6 1 1 3 4 4 4 0 Flagella accessory protein C (FlaC) CENP-Q PF13094.1 EGC38901.1 - 8.6 6.3 9.5 14 5.6 6.4 1.5 1 1 0 1 1 1 0 CENP-Q, a CENPA-CAD centromere complex subunit Peptidase_C71 PF12386.3 EGC38902.1 - 1.3e-05 24.6 4.1 0.00038 19.9 0.1 2.7 2 0 0 2 2 2 2 Pseudomurein endo-isopeptidase Pei DUF3430 PF11912.3 EGC38903.1 - 8.2e-18 64.9 16.7 9.3e-18 64.8 11.6 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Peptidase_M16_C PF05193.16 EGC38904.1 - 8.5e-26 90.7 0.2 7.4e-25 87.6 0.0 2.1 2 0 0 2 2 2 1 Peptidase M16 inactive domain Peptidase_M16 PF00675.15 EGC38904.1 - 2e-15 56.8 0.1 5.1e-15 55.5 0.0 1.8 2 0 0 2 2 2 1 Insulinase (Peptidase family M16) Rotamase_2 PF13145.1 EGC38904.1 - 0.15 12.7 1.0 0.39 11.3 0.7 1.7 1 0 0 1 1 1 0 PPIC-type PPIASE domain AAA_12 PF13087.1 EGC38905.1 - 2.2e-26 92.4 0.0 1.3e-25 89.9 0.0 2.4 2 0 0 2 2 2 1 AAA domain T2SE PF00437.15 EGC38905.1 - 0.022 13.6 0.0 0.053 12.4 0.0 1.5 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_29 PF13555.1 EGC38905.1 - 0.052 13.0 0.0 0.12 11.8 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_19 PF13245.1 EGC38905.1 - 0.37 10.5 0.0 11 5.8 0.0 2.6 3 0 0 3 3 3 0 Part of AAA domain AAA_30 PF13604.1 EGC38905.1 - 0.41 10.1 0.0 0.82 9.2 0.0 1.5 1 0 0 1 1 1 0 AAA domain RhoGEF PF00621.15 EGC38908.1 - 6.1e-48 163.0 10.9 6.1e-48 163.0 7.6 2.4 2 0 0 2 2 2 1 RhoGEF domain PH PF00169.24 EGC38908.1 - 6.6e-15 55.1 9.7 1.9e-14 53.7 0.2 4.1 2 1 0 2 2 2 1 PH domain PH_8 PF15409.1 EGC38908.1 - 1.9e-05 24.6 0.4 6.8e-05 22.8 0.3 2.0 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EGC38908.1 - 0.00041 20.5 0.7 0.00041 20.5 0.5 4.1 3 1 1 4 4 4 1 Pleckstrin homology domain LSM PF01423.17 EGC38909.1 - 2.2e-08 33.4 0.3 3.8e-08 32.7 0.2 1.3 1 0 0 1 1 1 1 LSM domain Rhamnogal_lyase PF06045.6 EGC38909.1 - 0.065 12.5 0.0 0.072 12.3 0.0 1.1 1 0 0 1 1 1 0 Rhamnogalacturonate lyase family DUF1256 PF06866.6 EGC38909.1 - 0.08 12.1 0.1 0.1 11.7 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1256) UPF0552 PF10574.4 EGC38910.1 - 3.4e-67 226.1 0.4 3.8e-67 226.0 0.3 1.0 1 0 0 1 1 1 1 Uncharacterised protein family UPF0552 IBN_N PF03810.14 EGC38910.1 - 0.04 13.8 0.0 0.14 12.1 0.0 1.9 2 0 0 2 2 2 0 Importin-beta N-terminal domain DUF4175 PF13779.1 EGC38911.1 - 9.5 3.7 9.7 12 3.4 6.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) F-box-like PF12937.2 EGC38912.1 - 1.7e-08 34.0 0.3 6e-08 32.2 0.1 2.0 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC38912.1 - 2e-08 33.6 1.7 9.5e-08 31.5 0.1 3.0 3 0 0 3 3 3 1 F-box domain LRR_8 PF13855.1 EGC38912.1 - 0.018 14.7 37.4 0.021 14.5 0.4 7.3 8 1 0 8 8 8 0 Leucine rich repeat EF-hand_6 PF13405.1 EGC38913.1 - 2e-12 45.8 11.0 0.0023 17.6 0.1 4.4 4 1 0 4 4 4 3 EF-hand domain EF-hand_7 PF13499.1 EGC38913.1 - 8.9e-11 41.7 12.8 4.1e-05 23.6 5.3 3.4 2 1 1 3 3 3 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC38913.1 - 9.7e-11 40.1 14.9 0.0011 18.0 0.5 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC38913.1 - 2.5e-07 30.2 6.6 0.00065 19.2 0.1 3.5 3 1 0 3 3 3 2 EF-hand domain pair EF-hand_5 PF13202.1 EGC38913.1 - 5.1e-06 25.5 8.8 0.00084 18.5 0.1 3.9 3 1 0 3 3 3 2 EF hand SPARC_Ca_bdg PF10591.4 EGC38913.1 - 0.078 13.0 6.7 6.5 6.8 2.7 2.5 2 1 0 2 2 2 0 Secreted protein acidic and rich in cysteine Ca binding region Baculo_DNA_bind PF04786.7 EGC38913.1 - 0.36 9.9 4.3 0.7 8.9 0.2 2.1 2 0 0 2 2 2 0 ssDNA binding protein Band_7 PF01145.20 EGC38914.1 - 0.0025 17.7 0.9 0.0043 16.9 0.5 1.4 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF2837 PF10997.3 EGC38914.1 - 0.099 11.7 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2837) Collagen_bind PF05737.7 EGC38914.1 - 0.17 12.0 2.2 3.8 7.6 0.3 2.7 2 1 0 2 2 2 0 Collagen binding domain PseudoU_synth_1 PF01416.15 EGC38915.1 - 6.4e-22 77.9 0.0 4e-13 49.7 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase DUF2344 PF10105.4 EGC38915.1 - 0.058 12.8 0.0 0.15 11.5 0.0 1.7 1 0 0 1 1 1 0 Uncharacterized protein conserved in bacteria (DUF2344) YhhN PF07947.9 EGC38916.1 - 2.8e-09 36.6 6.1 9.6e-06 25.0 0.4 2.7 3 0 0 3 3 3 2 YhhN-like protein Menin PF05053.8 EGC38916.1 - 4.5 5.3 9.9 6.7 4.7 6.9 1.2 1 0 0 1 1 1 0 Menin COesterase PF00135.23 EGC38917.1 - 5.7e-123 411.4 0.0 6.6e-123 411.2 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC38917.1 - 0.0064 16.0 0.0 0.013 15.0 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC38917.1 - 0.12 11.5 0.0 0.2 10.8 0.0 1.3 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF1664 PF07889.7 EGC38918.1 - 5.9 6.7 6.9 13 5.5 4.5 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF1664) RNA_pol_Rpb6 PF01192.17 EGC38919.1 - 3.4e-20 71.5 0.2 5.7e-20 70.8 0.1 1.3 1 0 0 1 1 1 1 RNA polymerase Rpb6 GAGA_bind PF06217.7 EGC38920.1 - 0.0088 16.0 5.2 0.011 15.7 3.6 1.0 1 0 0 1 1 1 1 GAGA binding protein-like family DUF4557 PF15101.1 EGC38920.1 - 0.031 14.1 9.1 0.04 13.7 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) MMR1 PF08505.5 EGC38920.1 - 0.15 12.1 8.8 0.16 11.9 6.1 1.1 1 0 0 1 1 1 0 Mitochondrial Myo2 receptor-related protein Neur_chan_memb PF02932.11 EGC38920.1 - 0.33 10.7 2.2 0.39 10.5 1.5 1.1 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DDHD PF02862.12 EGC38920.1 - 0.36 10.5 5.9 0.43 10.3 4.1 1.1 1 0 0 1 1 1 0 DDHD domain DUF1510 PF07423.6 EGC38920.1 - 0.37 10.1 13.9 0.45 9.8 9.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Astro_capsid PF03115.9 EGC38920.1 - 0.5 8.5 5.3 0.54 8.4 3.7 1.1 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Med15 PF09606.5 EGC38920.1 - 0.63 8.1 19.5 0.7 8.0 13.5 1.0 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal TRAP_alpha PF03896.11 EGC38920.1 - 0.79 8.6 8.3 0.98 8.3 5.8 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit Peptidase_S49_N PF08496.5 EGC38920.1 - 1.5 8.6 8.5 2 8.1 5.9 1.2 1 0 0 1 1 1 0 Peptidase family S49 N-terminal Sec62 PF03839.11 EGC38920.1 - 1.8 7.8 5.5 2.8 7.3 3.8 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 Formyl_trans_N PF00551.14 EGC38920.1 - 3 7.3 6.4 4.1 6.9 4.4 1.1 1 0 0 1 1 1 0 Formyl transferase DUF4175 PF13779.1 EGC38920.1 - 3.5 5.1 17.7 4.1 4.9 12.3 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) AAA_18 PF13238.1 EGC38920.1 - 7.6 6.8 6.6 17 5.7 4.6 1.6 1 1 0 1 1 1 0 AAA domain PDDEXK_5 PF11645.3 EGC38921.1 - 0.006 16.2 0.1 0.011 15.4 0.1 1.4 1 0 0 1 1 1 1 PD-(D/E)XK endonuclease SelR PF01641.13 EGC38922.1 - 2.6e-50 169.2 0.0 3e-50 169.0 0.0 1.0 1 0 0 1 1 1 1 SelR domain GFA PF04828.9 EGC38922.1 - 0.061 13.2 2.2 1.1 9.1 0.0 2.2 1 1 0 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme RIG-I_C-RD PF11648.3 EGC38922.1 - 0.13 12.1 0.5 0.85 9.5 0.1 1.9 2 0 0 2 2 2 0 C-terminal domain of RIG-I zf-Mss51 PF13824.1 EGC38922.1 - 0.13 12.1 4.0 0.42 10.5 0.1 2.8 2 1 1 3 3 3 0 Zinc-finger of mitochondrial splicing suppressor 51 Zn_Tnp_IS1595 PF12760.2 EGC38922.1 - 0.14 11.9 2.6 3.7 7.4 0.0 2.3 2 0 0 2 2 2 0 Transposase zinc-ribbon domain Auto_anti-p27 PF06677.7 EGC38922.1 - 0.36 10.6 0.1 0.36 10.6 0.1 2.5 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) Yippee-Mis18 PF03226.9 EGC38922.1 - 0.48 10.4 3.3 6.3 6.9 2.3 2.1 1 1 0 1 1 1 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly DZR PF12773.2 EGC38922.1 - 0.6 9.9 6.3 5.1 6.9 4.4 2.2 1 1 0 1 1 1 0 Double zinc ribbon Zn-ribbon_8 PF09723.5 EGC38922.1 - 0.73 9.8 3.2 16 5.5 0.4 2.4 2 0 0 2 2 2 0 Zinc ribbon domain Ribosomal_L37e PF01907.14 EGC38922.1 - 1.2 8.9 6.4 2.4 8.0 0.2 2.3 2 0 0 2 2 2 0 Ribosomal protein L37e DNA_RNApol_7kD PF03604.8 EGC38922.1 - 2 7.9 6.2 11 5.5 0.1 2.6 2 0 0 2 2 2 0 DNA directed RNA polymerase, 7 kDa subunit FUSC_2 PF13515.1 EGC38923.1 - 9.5e-15 54.6 13.7 9.5e-15 54.6 9.5 2.4 2 0 0 2 2 2 1 Fusaric acid resistance protein-like ALMT PF11744.3 EGC38923.1 - 4e-12 45.5 13.8 4e-12 45.5 9.6 2.9 2 1 0 2 2 2 1 Aluminium activated malate transporter Syntaxin-6_N PF09177.6 EGC38923.1 - 0.12 12.8 4.6 2.4 8.6 3.2 2.9 1 1 0 1 1 1 0 Syntaxin 6, N-terminal FUSC PF04632.7 EGC38923.1 - 0.15 10.4 7.2 0.24 9.7 5.0 1.2 1 0 0 1 1 1 0 Fusaric acid resistance protein family BTB PF00651.26 EGC38924.1 - 1.8e-13 50.4 3.4 4.1e-12 46.0 0.9 3.2 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EGC38924.1 - 7.3e-11 41.8 1.7 8.3e-08 32.0 0.1 2.7 2 0 0 2 2 2 2 BTB And C-terminal Kelch CENP-B_dimeris PF09026.5 EGC38924.1 - 0.17 12.1 5.7 0.11 12.6 2.0 2.1 2 0 0 2 2 2 0 Centromere protein B dimerisation domain GATA PF00320.22 EGC38925.1 - 9.4e-17 60.0 5.7 2.9e-16 58.5 4.0 1.9 1 0 0 1 1 1 1 GATA zinc finger DZR PF12773.2 EGC38925.1 - 0.046 13.5 0.9 0.13 12.1 0.6 1.7 1 0 0 1 1 1 0 Double zinc ribbon zf-ribbon_3 PF13248.1 EGC38925.1 - 0.14 11.4 1.9 0.29 10.3 1.3 1.6 1 0 0 1 1 1 0 zinc-ribbon domain ATP-synt_ab PF00006.20 EGC38926.1 - 3.4e-62 209.7 0.0 5.3e-62 209.1 0.0 1.3 1 0 0 1 1 1 1 ATP synthase alpha/beta family, nucleotide-binding domain ATP-synt_ab_C PF00306.22 EGC38926.1 - 3e-24 85.6 3.1 3.6e-24 85.3 0.7 2.2 1 1 1 2 2 2 1 ATP synthase alpha/beta chain, C terminal domain ATP-synt_ab_N PF02874.18 EGC38926.1 - 7.3e-18 64.5 0.9 7.9e-17 61.2 0.6 2.4 1 1 0 1 1 1 1 ATP synthase alpha/beta family, beta-barrel domain DUF258 PF03193.11 EGC38926.1 - 0.0025 17.0 0.1 0.0056 15.8 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_22 PF13401.1 EGC38926.1 - 0.0047 17.0 0.0 0.062 13.4 0.0 2.5 2 0 0 2 2 2 1 AAA domain MobB PF03205.9 EGC38926.1 - 0.0099 15.5 0.4 1.4 8.6 0.1 3.0 3 0 0 3 3 3 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGC38926.1 - 0.016 15.1 0.5 0.058 13.3 0.0 2.1 2 0 0 2 2 2 0 AAA ATPase domain VitK2_biosynth PF02621.9 EGC38926.1 - 0.018 14.2 0.0 0.048 12.8 0.0 1.7 2 0 0 2 2 2 0 Menaquinone biosynthesis NACHT PF05729.7 EGC38926.1 - 0.024 14.3 0.1 0.078 12.6 0.0 1.8 1 0 0 1 1 1 0 NACHT domain NB-ARC PF00931.17 EGC38926.1 - 0.028 13.3 0.6 0.095 11.5 0.1 2.0 2 0 0 2 2 2 0 NB-ARC domain AAA_25 PF13481.1 EGC38926.1 - 0.028 13.8 0.4 0.12 11.7 0.0 2.3 2 0 0 2 2 2 0 AAA domain KaiC PF06745.8 EGC38926.1 - 0.032 13.3 0.2 0.078 12.0 0.1 1.7 1 0 0 1 1 1 0 KaiC RNA_helicase PF00910.17 EGC38926.1 - 0.043 13.9 0.0 0.38 10.9 0.0 2.5 3 0 0 3 3 3 0 RNA helicase Arch_ATPase PF01637.13 EGC38926.1 - 0.046 13.4 0.4 0.39 10.3 0.0 2.3 2 0 0 2 2 2 0 Archaeal ATPase AAA PF00004.24 EGC38926.1 - 0.096 12.8 0.0 1 9.5 0.0 2.6 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Acyltransferase PF01553.16 EGC38927.1 - 2.8e-19 68.8 0.0 4.5e-19 68.1 0.0 1.3 1 0 0 1 1 1 1 Acyltransferase Nup54 PF13874.1 EGC38928.1 - 1.9e-33 115.0 6.4 1.9e-33 115.0 4.4 2.3 2 0 0 2 2 2 1 Nucleoporin complex subunit 54 Nucleoporin_FG PF13634.1 EGC38928.1 - 1.4e-09 38.1 88.5 2.1e-07 31.1 27.8 2.7 2 1 1 3 3 3 2 Nucleoporin FG repeat region Collagen PF01391.13 EGC38928.1 - 0.36 10.4 7.3 0.074 12.6 1.6 2.1 2 1 0 2 2 2 0 Collagen triple helix repeat (20 copies) DUF1917 PF08939.5 EGC38928.1 - 2.9 7.5 8.6 5.9 6.5 5.8 1.6 1 1 0 1 1 1 0 Domain of unknown function (DUF1917) COX6B PF02297.12 EGC38929.1 - 3.3e-18 65.4 8.1 3.3e-18 65.4 5.6 1.5 2 0 0 2 2 2 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EGC38929.1 - 0.0014 18.4 6.0 0.0014 18.4 4.2 2.2 2 1 1 3 3 3 1 CHCH domain DUF1903 PF08991.5 EGC38929.1 - 0.09 12.9 2.5 0.13 12.4 1.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1903) Orn_Arg_deC_N PF02784.11 EGC38930.1 - 4.2e-41 140.7 0.0 5.4e-41 140.4 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain Orn_DAP_Arg_deC PF00278.17 EGC38930.1 - 1.9e-15 56.6 0.0 2.7e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase, C-terminal sheet domain IBN_N PF03810.14 EGC38931.1 - 7.8e-15 54.5 0.8 1.8e-12 47.0 0.1 3.6 3 0 0 3 3 3 1 Importin-beta N-terminal domain Cse1 PF08506.5 EGC38931.1 - 2.4e-07 29.6 5.0 1.1e-06 27.4 0.1 3.5 3 1 1 4 4 4 1 Cse1 Xpo1 PF08389.7 EGC38931.1 - 0.00019 21.3 2.2 0.00019 21.3 1.5 3.7 3 1 0 3 3 3 1 Exportin 1-like protein HEAT_2 PF13646.1 EGC38931.1 - 0.00042 20.5 0.1 0.088 13.1 0.0 3.1 2 1 0 2 2 2 1 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC38931.1 - 0.0095 16.3 0.9 1.1 9.7 0.0 4.4 4 0 0 4 4 4 1 Vacuolar 14 Fab1-binding region ELO PF01151.13 EGC38932.1 - 8.7e-53 179.1 21.5 1e-50 172.4 14.9 2.0 1 1 0 1 1 1 1 GNS1/SUR4 family LrgB PF04172.11 EGC38932.1 - 9.4 5.3 7.5 1.3 8.1 0.5 2.2 2 0 0 2 2 2 0 LrgB-like family Tetraspannin PF00335.15 EGC38933.1 - 8.3e-27 93.8 10.6 1e-26 93.6 7.4 1.1 1 0 0 1 1 1 1 Tetraspanin family G0-G1_switch_2 PF15103.1 EGC38933.1 - 0.001 19.2 0.4 0.94 9.7 0.2 2.3 2 0 0 2 2 2 2 G0/G1 switch protein 2 DUF1206 PF06724.6 EGC38933.1 - 0.0019 17.8 2.7 0.0019 17.8 1.8 2.6 3 0 0 3 3 3 1 Domain of Unknown Function (DUF1206) DUF373 PF04123.8 EGC38933.1 - 0.018 14.1 4.0 0.031 13.3 2.7 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF373) DUF2976 PF11190.3 EGC38933.1 - 0.023 14.2 1.5 0.023 14.2 1.1 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2976) FA_desaturase PF00487.19 EGC38933.1 - 0.088 12.2 1.0 0.13 11.6 0.7 1.2 1 0 0 1 1 1 0 Fatty acid desaturase DUF4234 PF14018.1 EGC38933.1 - 1.3 8.8 5.8 26 4.6 3.5 2.6 2 1 0 2 2 2 0 Domain of unknown function (DUF4234) DUF4064 PF13273.1 EGC38933.1 - 1.4 9.0 13.6 0.73 9.9 6.7 2.3 2 1 0 2 2 2 0 Protein of unknown function (DUF4064) DUF3357 PF11837.3 EGC38933.1 - 3.4 7.5 4.3 6.3 6.6 0.0 2.5 3 0 0 3 3 2 0 Domain of unknown function (DUF3357) UPF0197 PF05251.7 EGC38933.1 - 4.7 7.5 10.3 0.23 11.7 2.9 2.0 2 0 0 2 2 2 0 Uncharacterised protein family (UPF0197) DUF4131 PF13567.1 EGC38933.1 - 8.6 5.7 13.0 0.18 11.1 1.1 2.7 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Med27 PF11571.3 EGC38934.1 - 1.9e-20 72.7 0.1 1.9e-20 72.7 0.1 3.5 2 1 0 2 2 2 1 Mediator complex subunit 27 HCO3_cotransp PF00955.16 EGC38934.1 - 5.4 5.5 8.4 7.8 5.0 5.8 1.3 1 0 0 1 1 1 0 HCO3- transporter family zf-CHY PF05495.7 EGC38935.1 - 6.9e-14 51.7 19.7 9.5e-14 51.3 13.6 1.2 1 0 0 1 1 1 1 CHY zinc finger zf-RING_3 PF14369.1 EGC38935.1 - 0.00033 20.5 6.2 0.044 13.7 1.2 2.4 2 0 0 2 2 2 2 zinc-finger Zn-ribbon_8 PF09723.5 EGC38935.1 - 0.0063 16.4 3.1 0.0063 16.4 2.2 2.5 2 1 0 2 2 2 1 Zinc ribbon domain zinc_ribbon_2 PF13240.1 EGC38935.1 - 0.016 14.6 5.6 0.3 10.6 0.2 2.9 2 1 0 2 2 2 0 zinc-ribbon domain Yippee-Mis18 PF03226.9 EGC38935.1 - 0.021 14.8 1.7 1.6 8.8 0.3 2.4 2 1 0 2 2 2 0 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly C1_4 PF07975.7 EGC38935.1 - 0.033 14.1 3.2 0.033 14.1 2.2 2.8 1 1 2 3 3 3 0 TFIIH C1-like domain DUF1451 PF07295.6 EGC38935.1 - 0.078 12.7 8.9 0.11 12.2 6.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1451) RNHCP PF12647.2 EGC38935.1 - 0.15 11.8 6.1 0.4 10.5 1.0 2.2 1 1 1 2 2 2 0 RNHCP domain zf-C2H2_6 PF13912.1 EGC38935.1 - 0.23 11.3 0.2 0.23 11.3 0.1 3.3 3 1 1 4 4 4 0 C2H2-type zinc finger zf-ribbon_3 PF13248.1 EGC38935.1 - 0.52 9.6 4.8 1.7 7.9 1.8 2.4 2 1 0 2 2 2 0 zinc-ribbon domain DZR PF12773.2 EGC38935.1 - 0.72 9.7 9.1 5.2 6.9 6.3 2.3 1 1 0 1 1 1 0 Double zinc ribbon zf-C2H2 PF00096.21 EGC38935.1 - 1.2 9.6 12.3 2 8.9 0.6 3.5 3 0 0 3 3 3 0 Zinc finger, C2H2 type LIM PF00412.17 EGC38935.1 - 1.5 8.9 14.8 3.1 7.9 7.6 2.4 1 1 1 2 2 2 0 LIM domain NOB1_Zn_bind PF08772.6 EGC38935.1 - 5.4 6.9 8.8 35 4.3 6.1 2.2 1 1 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like Zn_Tnp_IS1595 PF12760.2 EGC38935.1 - 5.5 6.8 13.9 11 5.9 0.1 2.7 2 1 1 3 3 3 0 Transposase zinc-ribbon domain Evr1_Alr PF04777.8 EGC38935.1 - 9.9 6.1 11.0 4.4e+02 0.8 7.5 2.7 1 1 0 1 1 1 0 Erv1 / Alr family Epimerase PF01370.16 EGC38936.1 - 3.8e-56 190.1 0.0 5e-56 189.7 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGC38936.1 - 6e-07 28.6 0.0 2.4e-05 23.3 0.0 2.1 2 0 0 2 2 2 2 RmlD substrate binding domain Polysacc_synt_2 PF02719.10 EGC38936.1 - 2.3e-05 23.4 1.3 0.00011 21.2 0.0 2.3 2 1 1 3 3 3 1 Polysaccharide biosynthesis protein Methyltransf_18 PF12847.2 EGC38937.1 - 6.6e-07 29.9 0.0 2e-06 28.3 0.0 1.7 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC38937.1 - 3.3e-05 23.5 0.1 5.7e-05 22.7 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain DOT1 PF08123.8 EGC38937.1 - 8.9e-05 21.8 0.8 0.00035 19.9 0.6 1.8 1 1 0 1 1 1 1 Histone methylation protein DOT1 Methyltransf_26 PF13659.1 EGC38937.1 - 0.00014 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_3 PF01596.12 EGC38937.1 - 0.0002 20.4 1.1 0.00025 20.1 0.2 1.5 2 0 0 2 2 2 1 O-methyltransferase Methyltransf_12 PF08242.7 EGC38937.1 - 0.00038 20.8 0.2 0.0017 18.7 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain CheR PF01739.13 EGC38937.1 - 0.0036 16.6 1.1 0.0091 15.2 0.6 1.6 1 1 1 2 2 2 1 CheR methyltransferase, SAM binding domain Methyltransf_11 PF08241.7 EGC38937.1 - 0.018 15.5 0.0 0.043 14.2 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain CmcI PF04989.7 EGC38937.1 - 0.027 13.7 0.0 0.043 13.1 0.0 1.3 1 0 0 1 1 1 0 Cephalosporin hydroxylase CpXC PF14353.1 EGC38937.1 - 0.055 13.4 0.0 0.19 11.7 0.0 1.9 2 0 0 2 2 2 0 CpXC protein Methyltransf_9 PF08003.6 EGC38937.1 - 0.058 12.0 0.0 0.099 11.3 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1698) DUF1624 PF07786.7 EGC38938.1 - 2.4e-07 30.3 11.2 2.4e-07 30.3 7.8 2.5 1 1 1 2 2 2 1 Protein of unknown function (DUF1624) Microcin PF03526.8 EGC38939.1 - 0.021 14.4 2.7 0.14 11.7 0.5 2.2 1 1 1 2 2 2 0 Colicin E1 (microcin) immunity protein DUF866 PF05907.8 EGC38940.1 - 1.2e-42 145.1 4.2 1.3e-42 144.9 2.9 1.0 1 0 0 1 1 1 1 Eukaryotic protein of unknown function (DUF866) Ribosomal_S27e PF01667.12 EGC38940.1 - 0.041 13.4 3.0 0.81 9.2 0.3 2.3 2 0 0 2 2 2 0 Ribosomal protein S27 T4_baseplate PF12322.3 EGC38940.1 - 0.087 12.0 3.4 1.2 8.3 0.3 2.2 1 1 1 2 2 2 0 T4 bacteriophage base plate protein Lar_restr_allev PF14354.1 EGC38940.1 - 0.088 13.1 1.8 1.4 9.2 0.1 2.3 1 1 1 2 2 2 0 Restriction alleviation protein Lar zinc_ribbon_5 PF13719.1 EGC38940.1 - 0.09 12.3 1.3 0.51 9.9 0.1 2.3 2 0 0 2 2 2 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGC38940.1 - 0.14 11.3 1.8 0.47 9.7 0.1 2.2 2 0 0 2 2 2 0 zinc-ribbon domain zf-AN1 PF01428.11 EGC38940.1 - 0.16 11.8 4.7 0.71 9.7 0.4 2.4 2 0 0 2 2 2 0 AN1-like Zinc finger Arv1 PF04161.8 EGC38940.1 - 0.33 10.8 2.8 0.48 10.2 0.1 2.0 1 1 1 2 2 2 0 Arv1-like family zinc_ribbon_4 PF13717.1 EGC38940.1 - 0.38 10.4 3.3 0.75 9.5 0.3 2.3 2 0 0 2 2 2 0 zinc-ribbon domain TF_Zn_Ribbon PF08271.7 EGC38940.1 - 1.4 8.3 6.1 8.7 5.7 0.2 3.0 3 0 0 3 3 3 0 TFIIB zinc-binding Cyt-b5 PF00173.23 EGC38941.1 - 3e-22 78.2 0.1 9.7e-22 76.5 0.0 1.8 2 0 0 2 2 2 1 Cytochrome b5-like Heme/Steroid binding domain NIF PF03031.13 EGC38942.1 - 4e-20 72.0 0.4 9.2e-20 70.9 0.3 1.6 1 0 0 1 1 1 1 NLI interacting factor-like phosphatase DUF3899 PF13038.1 EGC38942.1 - 0.03 14.4 7.1 1.4 9.1 0.3 2.5 1 1 1 2 2 2 0 Domain of unknown function (DUF3899) DUF2370 PF10176.4 EGC38942.1 - 0.065 12.5 0.0 0.15 11.3 0.0 1.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2370) Tim54 PF11711.3 EGC38942.1 - 0.36 9.3 6.6 0.52 8.8 4.5 1.2 1 0 0 1 1 1 0 Inner membrane protein import complex subunit Tim54 DDHD PF02862.12 EGC38942.1 - 1.1 9.0 6.4 1.9 8.2 4.5 1.3 1 0 0 1 1 1 0 DDHD domain YqfQ PF14181.1 EGC38942.1 - 1.8 8.5 10.7 3.1 7.8 7.4 1.3 1 0 0 1 1 1 0 YqfQ-like protein Sec62 PF03839.11 EGC38942.1 - 2.7 7.3 11.8 4.2 6.6 8.2 1.3 1 0 0 1 1 1 0 Translocation protein Sec62 DUF1510 PF07423.6 EGC38942.1 - 5 6.4 15.3 8 5.7 10.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) ETRAMP PF09716.5 EGC38942.1 - 6 6.8 11.8 1e+02 2.9 8.2 2.5 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Tho2 PF11262.3 EGC38942.1 - 9.8 5.1 12.3 2.7 6.9 5.8 1.9 2 0 0 2 2 2 0 Transcription factor/nuclear export subunit protein 2 BRAP2 PF07576.7 EGC38943.1 - 1.4e-25 88.9 0.5 4.2e-25 87.4 0.3 1.8 1 0 0 1 1 1 1 BRCA1-associated protein 2 zf-UBP PF02148.14 EGC38943.1 - 2.1e-19 69.3 5.0 2.1e-19 69.3 3.4 2.1 2 0 0 2 2 2 1 Zn-finger in ubiquitin-hydrolases and other protein zf-RING_2 PF13639.1 EGC38943.1 - 6.7e-11 41.8 9.9 6.7e-11 41.8 6.9 2.1 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC38943.1 - 3.1e-05 24.0 5.4 3.1e-05 24.0 3.7 2.1 2 0 0 2 2 2 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC38943.1 - 4.3e-05 23.1 7.9 4.3e-05 23.1 5.5 2.5 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC38943.1 - 0.00023 20.7 7.4 0.00023 20.7 5.1 2.5 3 0 0 3 3 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC38943.1 - 0.00026 20.9 9.0 0.00026 20.9 6.2 2.5 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC38943.1 - 0.0097 15.6 1.6 0.0097 15.6 1.1 2.7 1 1 1 2 2 2 1 RING-type zinc-finger zf-Apc11 PF12861.2 EGC38943.1 - 0.014 15.2 7.0 0.014 15.2 4.8 1.8 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC38943.1 - 0.023 14.2 5.6 0.059 12.9 3.9 1.7 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain IncA PF04156.9 EGC38943.1 - 9.3 5.7 11.9 15 5.1 8.3 1.3 1 0 0 1 1 1 0 IncA protein Kelch_3 PF13415.1 EGC38944.1 - 5.8e-49 163.2 1.6 2.6e-12 46.5 0.0 6.4 6 0 0 6 6 6 5 Galactose oxidase, central domain Kelch_4 PF13418.1 EGC38944.1 - 1.3e-47 159.3 5.2 2.1e-10 40.2 0.0 6.3 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC38944.1 - 1e-39 133.7 3.1 1.9e-06 27.2 0.1 6.4 6 0 0 6 6 6 6 Kelch motif Kelch_5 PF13854.1 EGC38944.1 - 2.1e-34 116.9 0.0 1e-05 25.3 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_6 PF13964.1 EGC38944.1 - 8.4e-34 114.3 6.3 1.6e-05 24.8 0.1 6.6 5 1 1 6 6 6 6 Kelch motif Kelch_2 PF07646.10 EGC38944.1 - 2.4e-33 112.6 8.9 7.3e-07 28.7 0.1 6.3 6 0 0 6 6 6 6 Kelch motif FRG1 PF06229.7 EGC38944.1 - 0.032 13.7 0.0 0.25 10.8 0.0 2.0 2 0 0 2 2 2 0 FRG1-like family PRANC PF09372.5 EGC38944.1 - 0.13 12.2 10.4 0.62 10.0 0.1 2.7 2 1 0 2 2 2 0 PRANC domain AAA_18 PF13238.1 EGC38945.1 - 7.6e-14 52.1 0.4 1.4e-13 51.2 0.2 1.5 1 1 0 1 1 1 1 AAA domain AAA_28 PF13521.1 EGC38945.1 - 6.9e-08 32.6 0.0 1e-07 32.0 0.0 1.2 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC38945.1 - 3.3e-06 27.0 0.0 0.00013 21.8 0.0 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC38945.1 - 7.8e-06 26.7 0.1 4.2e-05 24.3 0.0 1.9 1 1 1 2 2 2 1 AAA domain Thymidylate_kin PF02223.12 EGC38945.1 - 1.9e-05 24.1 2.1 0.00032 20.1 1.4 2.2 1 1 0 1 1 1 1 Thymidylate kinase dNK PF01712.14 EGC38945.1 - 0.00032 20.6 3.3 0.00052 19.9 2.3 1.4 1 1 0 1 1 1 1 Deoxynucleoside kinase AAA_22 PF13401.1 EGC38945.1 - 0.0029 17.7 0.1 0.02 15.0 0.0 2.1 1 1 1 2 2 2 1 AAA domain UPF0079 PF02367.12 EGC38945.1 - 0.0046 16.5 0.0 0.0082 15.7 0.0 1.4 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 SKI PF01202.17 EGC38945.1 - 0.0075 16.1 0.3 0.055 13.3 0.1 2.2 2 0 0 2 2 2 1 Shikimate kinase zf-CCCH PF00642.19 EGC38945.1 - 0.049 13.3 0.2 0.084 12.5 0.1 1.4 1 0 0 1 1 1 0 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Zeta_toxin PF06414.7 EGC38945.1 - 0.057 12.5 0.6 6 5.9 0.0 2.5 3 0 0 3 3 3 0 Zeta toxin ATP_bind_2 PF03668.10 EGC38945.1 - 0.13 11.3 0.2 11 4.9 0.1 2.2 1 1 1 2 2 2 0 P-loop ATPase protein family CoaE PF01121.15 EGC38945.1 - 0.25 10.7 2.5 0.4 10.0 0.0 2.3 3 0 0 3 3 3 0 Dephospho-CoA kinase Bromodomain PF00439.20 EGC38946.1 - 2.8e-20 72.0 0.1 6.3e-19 67.6 0.0 3.1 3 0 0 3 3 3 1 Bromodomain CAF-1_p150 PF11600.3 EGC38946.1 - 1.3e-07 31.2 23.6 1.3e-07 31.2 16.3 10.1 5 2 2 9 9 9 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal DUF2514 PF10721.4 EGC38946.1 - 8.2 6.1 15.6 31 4.2 10.8 2.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2514) Pribosyltran PF00156.22 EGC38947.1 - 2.4e-15 56.3 0.0 3.6e-15 55.7 0.0 1.2 1 0 0 1 1 1 1 Phosphoribosyl transferase domain UPRTase PF14681.1 EGC38947.1 - 0.00054 19.2 0.0 0.00072 18.8 0.0 1.2 1 0 0 1 1 1 1 Uracil phosphoribosyltransferase RRM_5 PF13893.1 EGC38948.1 - 0.00062 19.5 0.3 0.0032 17.2 0.2 2.0 1 1 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC38948.1 - 0.0041 16.7 0.0 0.011 15.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC38948.1 - 0.063 13.2 0.0 0.16 11.9 0.0 1.7 1 1 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DMAP1 PF05499.7 EGC38948.1 - 3.4 7.1 11.8 5.2 6.5 3.3 2.6 2 1 0 2 2 2 0 DNA methyltransferase 1-associated protein 1 (DMAP1) DUF2151 PF10221.4 EGC38949.1 - 2.9e-32 111.7 16.1 2.9e-22 78.6 4.1 3.0 1 1 0 2 2 2 2 Cell cycle and development regulator DUF1777 PF08648.7 EGC38950.1 - 0.0024 17.6 20.7 0.0024 17.6 14.3 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF1777) CAF-1_p150 PF11600.3 EGC38950.1 - 0.0027 17.0 40.0 0.0027 17.0 27.7 4.1 5 0 0 5 5 5 1 Chromatin assembly factor 1 complex p150 subunit, N-terminal Trypan_PARP PF05887.6 EGC38950.1 - 0.33 10.7 25.3 0.39 10.5 6.6 2.6 2 0 0 2 2 2 0 Procyclic acidic repetitive protein (PARP) PLDc_2 PF13091.1 EGC38951.1 - 9.4e-25 86.7 0.1 3.3e-16 59.1 0.0 3.0 2 1 0 2 2 2 2 PLD-like domain PLDc PF00614.17 EGC38951.1 - 0.00018 21.1 3.7 0.00053 19.6 0.1 2.9 3 0 0 3 3 3 1 Phospholipase D Active site motif DUF3739 PF12545.3 EGC38951.1 - 0.024 14.7 0.0 0.12 12.5 0.0 2.1 3 0 0 3 3 3 0 Filamentous haemagglutinin family outer membrane protein SUI1 PF01253.17 EGC38952.1 - 6.6e-19 67.5 1.1 2.6e-18 65.6 1.2 1.6 2 0 0 2 2 2 1 Translation initiation factor SUI1 DUF966 PF06136.8 EGC38952.1 - 0.0015 18.0 1.9 0.0016 17.9 1.3 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF966) CfAFP PF05264.6 EGC38952.1 - 0.046 13.4 0.1 0.046 13.4 0.1 2.4 2 1 0 3 3 3 0 Choristoneura fumiferana antifreeze protein (CfAFP) Pal1 PF08316.6 EGC38952.1 - 0.12 12.8 4.8 0.2 12.1 3.3 1.3 1 0 0 1 1 1 0 Pal1 cell morphology protein FNIP PF05725.7 EGC38953.1 - 1.8e-21 75.7 57.8 1.4e-11 44.1 0.7 10.8 9 2 4 13 13 13 10 FNIP Repeat Aldedh PF00171.17 EGC38954.1 - 1.2e-74 251.3 0.0 1.5e-74 251.0 0.0 1.0 1 0 0 1 1 1 1 Aldehyde dehydrogenase family ORC3_N PF07034.6 EGC38955.1 - 4.2e-25 88.4 4.3 4.2e-25 88.4 3.0 2.7 2 1 0 2 2 2 1 Origin recognition complex (ORC) subunit 3 N-terminus PHD PF00628.24 EGC38955.1 - 0.0072 15.9 8.2 0.0072 15.9 5.7 2.2 2 0 0 2 2 2 1 PHD-finger DUF3437 PF11919.3 EGC38955.1 - 0.029 14.0 1.0 0.81 9.4 0.1 3.3 3 1 1 4 4 4 0 Domain of unknown function (DUF3437) Prok-RING_1 PF14446.1 EGC38955.1 - 0.15 11.8 6.0 0.41 10.4 4.2 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 1 Utp11 PF03998.8 EGC38956.1 - 6.2e-54 183.3 17.3 6.9e-54 183.2 12.0 1.0 1 0 0 1 1 1 1 Utp11 protein DUF3357 PF11837.3 EGC38956.1 - 0.12 12.2 0.3 0.24 11.2 0.2 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3357) Fib_alpha PF08702.5 EGC38956.1 - 0.88 9.6 7.9 0.23 11.5 3.1 1.8 2 0 0 2 2 2 0 Fibrinogen alpha/beta chain family Pyridoxal_deC PF00282.14 EGC38957.1 - 8.7e-15 54.0 0.0 3.1e-06 25.8 0.0 3.1 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain FAD_binding_1 PF00667.15 EGC38958.1 - 4.4e-65 219.1 0.0 7e-65 218.5 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain Flavodoxin_1 PF00258.20 EGC38958.1 - 1.3e-32 112.7 0.1 3e-32 111.5 0.1 1.7 1 0 0 1 1 1 1 Flavodoxin NAD_binding_1 PF00175.16 EGC38958.1 - 8.7e-22 77.7 0.0 2.7e-21 76.1 0.0 1.9 1 0 0 1 1 1 1 Oxidoreductase NAD-binding domain RepC PF06504.6 EGC38958.1 - 0.016 14.1 0.2 0.23 10.3 0.1 2.1 2 0 0 2 2 2 0 Replication protein C (RepC) adh_short PF00106.20 EGC38958.1 - 0.038 13.8 0.0 0.07 13.0 0.0 1.4 1 0 0 1 1 1 0 short chain dehydrogenase FAD_binding_9 PF08021.6 EGC38958.1 - 0.053 13.4 0.0 0.24 11.3 0.0 2.1 2 0 0 2 2 2 0 Siderophore-interacting FAD-binding domain FAD_binding_6 PF00970.19 EGC38958.1 - 0.11 12.5 0.0 0.28 11.3 0.0 1.6 1 0 0 1 1 1 0 Oxidoreductase FAD-binding domain Pro-kuma_activ PF09286.6 EGC38959.1 - 2.6e-34 118.3 0.0 2.6e-34 118.3 0.0 1.7 2 0 0 2 2 2 1 Pro-kumamolisin, activation domain Peptidase_S8 PF00082.17 EGC38959.1 - 2e-05 23.8 0.0 3.8e-05 22.9 0.0 1.5 1 0 0 1 1 1 1 Subtilase family V_ATPase_I PF01496.14 EGC38959.1 - 0.35 8.6 16.1 0.47 8.2 11.1 1.3 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Exonuc_VII_L PF02601.10 EGC38959.1 - 0.41 9.7 13.4 0.66 9.1 9.3 1.4 1 0 0 1 1 1 0 Exonuclease VII, large subunit Neur_chan_memb PF02932.11 EGC38959.1 - 0.51 10.1 5.9 1 9.2 4.1 1.5 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region LMBR1 PF04791.11 EGC38959.1 - 0.76 8.2 6.6 1.1 7.8 4.6 1.2 1 0 0 1 1 1 0 LMBR1-like membrane protein IncA PF04156.9 EGC38959.1 - 1 8.9 11.3 2.7 7.5 7.8 1.8 1 0 0 1 1 1 0 IncA protein Pmp3 PF01679.12 EGC38960.1 - 1.7e-17 62.8 11.0 1.8e-17 62.7 7.7 1.0 1 0 0 1 1 1 1 Proteolipid membrane potential modulator TMEM238 PF15125.1 EGC38960.1 - 0.086 12.7 0.5 0.086 12.7 0.4 1.9 2 0 0 2 2 2 0 TMEM238 protein family DUF983 PF06170.7 EGC38960.1 - 0.26 11.4 2.9 0.28 11.3 2.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF983) Claudin_3 PF06653.6 EGC38961.1 - 0.22 11.2 14.1 11 5.6 7.1 3.1 1 1 1 2 2 2 0 Tight junction protein, Claudin-like TMEM192 PF14802.1 EGC38961.1 - 0.39 9.5 3.0 0.44 9.3 1.5 1.6 1 1 0 1 1 1 0 TMEM192 family DUF3593 PF12159.3 EGC38961.1 - 1.4 8.7 5.8 0.24 11.1 0.8 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF3593) DUF202 PF02656.10 EGC38961.1 - 2.5 8.3 11.5 0.49 10.6 0.4 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF202) DUF4293 PF14126.1 EGC38961.1 - 2.9 7.8 10.5 1.6 8.6 5.1 2.1 1 1 0 1 1 1 0 Domain of unknown function (DUF4293) DUF872 PF05915.7 EGC38961.1 - 6.6 6.6 6.5 1.5 8.6 1.2 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) NfeD PF01957.13 EGC38961.1 - 8 6.5 11.0 1.8e+02 2.1 6.8 2.8 2 1 0 2 2 2 0 NfeD-like C-terminal, partner-binding Peptidase_M1 PF01433.15 EGC38962.1 - 9e-139 462.8 0.5 1.4e-138 462.2 0.3 1.3 1 0 0 1 1 1 1 Peptidase family M1 ERAP1_C PF11838.3 EGC38962.1 - 4.4e-65 220.0 0.0 8.4e-65 219.1 0.0 1.5 1 0 0 1 1 1 1 ERAP1-like C-terminal domain Peptidase_MA_2 PF13485.1 EGC38962.1 - 1.1e-21 77.1 0.2 1.9e-21 76.4 0.1 1.3 1 0 0 1 1 1 1 Peptidase MA superfamily SprT-like PF10263.4 EGC38962.1 - 0.11 12.1 0.0 0.23 11.1 0.0 1.5 1 0 0 1 1 1 0 SprT-like family Ras PF00071.17 EGC38963.1 - 4.1e-49 166.0 0.0 4.8e-49 165.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC38963.1 - 9.1e-17 61.6 0.0 1.3e-16 61.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC38963.1 - 8.3e-09 34.9 0.0 1.1e-08 34.4 0.0 1.2 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC38963.1 - 0.00014 21.3 0.2 0.0017 17.8 0.0 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC38963.1 - 0.026 13.7 0.0 0.14 11.3 0.0 1.9 1 1 0 2 2 2 0 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC38963.1 - 0.027 14.4 0.0 0.042 13.7 0.0 1.4 1 1 0 1 1 1 0 50S ribosome-binding GTPase Gtr1_RagA PF04670.7 EGC38963.1 - 0.074 12.1 0.0 0.096 11.8 0.0 1.5 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region DUF3907 PF13047.1 EGC38963.1 - 0.081 12.5 0.0 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3907) PDDEXK_4 PF14281.1 EGC38964.1 - 0.014 15.2 0.0 0.016 15.0 0.0 1.1 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily UPF0203 PF05254.7 EGC38964.1 - 0.034 14.0 3.7 0.26 11.1 2.6 1.9 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0203) COX6B PF02297.12 EGC38964.1 - 0.042 13.8 2.7 0.12 12.3 1.9 1.7 1 1 0 1 1 1 0 Cytochrome oxidase c subunit VIb PMC2NT PF08066.7 EGC38964.1 - 0.047 13.9 0.0 0.056 13.7 0.0 1.1 1 0 0 1 1 1 0 PMC2NT (NUC016) domain CHCH PF06747.8 EGC38964.1 - 0.077 12.9 3.1 0.67 9.9 0.1 2.1 2 0 0 2 2 2 0 CHCH domain PyrBI_leader PF08052.6 EGC38964.1 - 0.08 12.7 0.3 0.17 11.6 0.0 1.7 2 0 0 2 2 2 0 PyrBI operon leader peptide DUF3045 PF11243.3 EGC38964.1 - 0.1 12.8 0.0 0.13 12.5 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3045) Pet191_N PF10203.4 EGC38964.1 - 0.21 11.6 2.5 1.3 9.0 1.7 1.9 1 1 0 1 1 1 0 Cytochrome c oxidase assembly protein PET191 DUF3128 PF11326.3 EGC38964.1 - 0.27 11.3 2.5 8.2 6.6 0.1 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF3128) FNIP PF05725.7 EGC38965.1 - 6.1e-54 179.7 42.2 8.2e-11 41.6 1.0 8.0 6 2 3 9 9 9 8 FNIP Repeat DUF1769 PF08588.5 EGC38965.1 - 0.27 11.2 5.2 6.5 6.7 0.1 4.5 3 2 2 5 5 5 0 Protein of unknown function (DUF1769) DUF3430 PF11912.3 EGC38966.1 - 8.2e-10 38.8 30.6 1.2e-09 38.3 21.2 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) WD40 PF00400.27 EGC38967.1 - 3.5e-12 45.7 5.6 0.00012 21.8 0.0 6.0 6 1 0 6 6 6 3 WD domain, G-beta repeat TFIIIC_delta PF12657.2 EGC38967.1 - 0.023 14.4 5.8 1.5 8.5 0.0 3.3 2 1 1 3 3 3 0 Transcription factor IIIC subunit delta N-term DSPc PF00782.15 EGC38968.1 - 1.1e-28 99.4 0.4 1.1e-28 99.4 0.3 2.5 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain LRR_4 PF12799.2 EGC38968.1 - 9.2e-25 85.7 43.2 1.7e-07 30.7 0.8 7.5 4 1 4 8 8 7 7 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC38968.1 - 1e-23 82.8 28.3 3.3e-08 33.1 1.1 5.0 2 1 2 4 4 4 4 Leucine rich repeat LRR_1 PF00560.28 EGC38968.1 - 2.3e-10 39.0 42.5 0.46 10.7 0.1 11.5 11 0 0 11 11 11 4 Leucine Rich Repeat LRR_7 PF13504.1 EGC38968.1 - 5.6e-07 28.7 20.4 11 6.7 0.0 10.0 10 0 0 10 10 10 1 Leucine rich repeat LRR_6 PF13516.1 EGC38968.1 - 3.2e-06 26.6 23.6 0.17 12.0 0.1 9.1 7 2 2 9 9 9 1 Leucine Rich repeat Y_phosphatase PF00102.22 EGC38968.1 - 0.0063 15.8 6.0 0.11 11.8 4.1 2.2 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGC38968.1 - 0.017 15.1 0.0 0.017 15.1 0.0 2.6 2 0 0 2 2 2 0 Inositol hexakisphosphate CDC27 PF09507.5 EGC38968.1 - 0.88 8.7 25.9 1.3 8.1 18.0 1.1 1 0 0 1 1 1 0 DNA polymerase subunit Cdc27 SprA-related PF12118.3 EGC38968.1 - 1.1 8.5 21.7 1.7 7.9 15.0 1.1 1 0 0 1 1 1 0 SprA-related family LRR_2 PF07723.8 EGC38968.1 - 8.9 6.9 8.0 1.2e+02 3.4 0.0 4.7 5 0 0 5 5 4 0 Leucine Rich Repeat CoA_transf_3 PF02515.12 EGC38969.1 - 4.3e-63 212.0 0.0 5.6e-63 211.6 0.0 1.1 1 0 0 1 1 1 1 CoA-transferase family III BRX_N PF13713.1 EGC38969.1 - 0.13 11.7 0.1 0.31 10.5 0.1 1.6 1 0 0 1 1 1 0 Transcription factor BRX N-terminal domain WD40 PF00400.27 EGC38970.1 - 3.7e-09 36.1 9.6 0.18 11.7 0.0 6.1 7 0 0 7 7 7 3 WD domain, G-beta repeat BBS2_Mid PF14783.1 EGC38970.1 - 0.0018 17.9 3.1 0.16 11.7 0.1 3.9 2 2 2 4 4 4 1 Ciliary BBSome complex subunit 2, middle region DUF977 PF06163.6 EGC38970.1 - 0.063 13.0 0.4 1.4 8.6 0.1 3.0 2 1 0 3 3 3 0 Bacterial protein of unknown function (DUF977) WD40 PF00400.27 EGC38971.1 - 7.1e-12 44.7 19.5 0.00084 19.1 0.1 6.3 7 0 0 7 7 7 5 WD domain, G-beta repeat eIF2A PF08662.6 EGC38971.1 - 0.0081 15.8 1.6 0.41 10.3 0.0 2.4 1 1 1 2 2 2 2 Eukaryotic translation initiation factor eIF2A Utp8 PF10395.4 EGC38971.1 - 0.033 12.5 0.1 0.087 11.1 0.1 1.6 1 1 1 2 2 2 0 Utp8 family CPSF_A PF03178.10 EGC38971.1 - 0.097 11.7 0.6 0.75 8.8 0.4 2.6 1 1 0 1 1 1 0 CPSF A subunit region RPN7 PF10602.4 EGC38972.1 - 2.9e-57 192.8 1.3 4.4e-57 192.3 0.9 1.3 1 0 0 1 1 1 1 26S proteasome subunit RPN7 PCI PF01399.22 EGC38972.1 - 1.1e-17 64.2 0.1 5e-17 62.1 0.0 2.2 2 0 0 2 2 2 1 PCI domain Sec3_C_2 PF15278.1 EGC38972.1 - 0.017 15.2 0.1 0.044 13.9 0.1 1.7 1 0 0 1 1 1 0 Sec3 exocyst complex subunit DUF1115 PF06544.7 EGC38972.1 - 0.056 13.1 0.8 0.096 12.3 0.1 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1115) FeoC PF09012.5 EGC38972.1 - 0.084 12.5 0.0 0.19 11.4 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator Ctr PF04145.10 EGC38973.1 - 2.6e-31 108.6 1.2 3e-31 108.4 0.8 1.1 1 0 0 1 1 1 1 Ctr copper transporter family DUF4229 PF14012.1 EGC38973.1 - 0.003 17.4 1.5 0.0061 16.4 1.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF4229) DUF457 PF04307.9 EGC38973.1 - 0.069 12.4 1.7 0.095 12.0 1.1 1.4 1 1 0 1 1 1 0 Predicted membrane-bound metal-dependent hydrolase (DUF457) YtpI PF14007.1 EGC38973.1 - 0.2 11.5 4.9 0.092 12.6 1.2 1.8 2 0 0 2 2 2 0 YtpI-like protein OppC_N PF12911.2 EGC38973.1 - 5.3 6.5 7.1 2 7.8 0.1 2.7 3 0 0 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C Cellulase PF00150.13 EGC38974.1 - 1.2e-32 113.2 5.5 1.2e-32 113.2 3.0 1.6 2 0 0 2 2 2 1 Cellulase (glycosyl hydrolase family 5) CBM49 PF09478.5 EGC38974.1 - 2.3e-17 62.8 5.6 2.9e-17 62.5 0.4 2.8 2 0 0 2 2 2 1 Carbohydrate binding domain CBM49 MSP1_C PF07462.6 EGC38974.1 - 8.4 4.6 8.6 12 4.1 5.9 1.1 1 0 0 1 1 1 0 Merozoite surface protein 1 (MSP1) C-terminus WGG PF10273.4 EGC38975.1 - 3.7e-23 81.3 0.1 1.1e-22 79.9 0.1 1.8 1 0 0 1 1 1 1 Pre-rRNA-processing protein TSR2 RRP7 PF12923.2 EGC38975.1 - 0.0012 18.9 1.9 0.0012 18.9 1.3 2.2 2 0 0 2 2 2 1 Ribosomal RNA-processing protein 7 (RRP7) DUF1910 PF08928.5 EGC38975.1 - 0.095 12.7 3.1 0.21 11.6 1.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1910) Calici_MSP PF05752.6 EGC38975.1 - 0.23 11.0 8.9 0.42 10.2 6.1 1.5 1 0 0 1 1 1 0 Calicivirus minor structural protein IncA PF04156.9 EGC38975.1 - 0.61 9.6 10.0 1 8.8 6.9 1.4 1 0 0 1 1 1 0 IncA protein Metallopep PF12044.3 EGC38975.1 - 4.5 5.6 6.4 6.2 5.1 4.4 1.2 1 0 0 1 1 1 0 Putative peptidase family Sec23_trunk PF04811.10 EGC38976.1 - 3.8e-19 69.0 1.1 3.1e-16 59.4 0.1 2.3 2 0 0 2 2 2 2 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGC38976.1 - 2.8e-11 42.7 0.3 1.9e-10 40.0 0.0 2.5 2 1 0 2 2 2 1 Sec23/Sec24 helical domain zf-Sec23_Sec24 PF04810.10 EGC38976.1 - 2.4e-09 36.5 2.2 5.4e-09 35.4 1.5 1.6 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_BS PF08033.7 EGC38976.1 - 0.0086 16.5 1.1 0.023 15.2 0.0 2.3 2 0 0 2 2 2 1 Sec23/Sec24 beta-sandwich domain C1_1 PF00130.17 EGC38976.1 - 0.52 10.0 2.4 1.1 9.0 1.7 1.4 1 0 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) AAA_28 PF13521.1 EGC38977.1 - 4.6e-28 98.2 0.0 5.3e-28 98.0 0.0 1.0 1 0 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC38977.1 - 0.014 16.2 0.1 0.021 15.6 0.1 1.5 1 1 0 1 1 1 0 AAA domain ATP-synt_ab PF00006.20 EGC38977.1 - 0.075 12.5 0.0 0.2 11.0 0.0 1.8 1 1 0 1 1 1 0 ATP synthase alpha/beta family, nucleotide-binding domain F-box PF00646.28 EGC38978.1 - 0.0057 16.2 2.8 0.025 14.2 0.3 2.9 3 0 0 3 3 3 1 F-box domain F-box-like PF12937.2 EGC38978.1 - 0.008 15.8 0.1 0.023 14.4 0.1 1.8 1 0 0 1 1 1 1 F-box-like Syntaxin-6_N PF09177.6 EGC38979.1 - 2.2 8.7 8.4 2.1 8.8 2.6 2.5 2 1 0 2 2 2 0 Syntaxin 6, N-terminal DUF4600 PF15372.1 EGC38979.1 - 8.1 6.6 12.9 2.7 8.1 0.4 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4600) Tyr-DNA_phospho PF06087.7 EGC38981.1 - 1.4e-31 109.5 16.5 2.4e-24 85.8 0.6 3.9 3 2 0 3 3 3 3 Tyrosyl-DNA phosphodiesterase Secretin_N_2 PF07655.8 EGC38981.1 - 0.0041 17.4 14.9 0.0041 17.4 10.3 6.0 4 1 0 4 4 4 1 Secretin N-terminal domain Cellulase PF00150.13 EGC38983.1 - 3.6e-29 101.8 0.3 5.8e-29 101.1 0.2 1.3 1 0 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) Glyco_hydro_42 PF02449.10 EGC38983.1 - 0.015 14.4 0.0 0.027 13.5 0.0 1.3 1 0 0 1 1 1 0 Beta-galactosidase Cellulase-like PF12876.2 EGC38983.1 - 0.061 13.7 0.0 0.2 12.1 0.0 2.0 1 0 0 1 1 1 0 Sugar-binding cellulase-like Raptor_N PF14538.1 EGC38984.1 - 7.8e-75 249.8 0.1 2.8e-74 248.1 0.0 2.0 1 0 0 1 1 1 1 Raptor N-terminal CASPase like domain WD40 PF00400.27 EGC38984.1 - 3e-12 45.9 9.2 0.25 11.3 0.1 6.7 6 1 0 6 6 6 5 WD domain, G-beta repeat HEAT PF02985.17 EGC38984.1 - 6.6e-10 38.2 6.1 0.0089 16.0 0.0 6.1 6 0 0 6 6 6 2 HEAT repeat HEAT_2 PF13646.1 EGC38984.1 - 1.5e-07 31.5 1.5 0.011 15.9 0.3 3.5 2 1 1 3 3 3 2 HEAT repeats HEAT_EZ PF13513.1 EGC38984.1 - 1.9e-05 24.9 2.1 0.91 10.1 0.1 4.0 4 0 0 4 4 4 2 HEAT-like repeat DUF2435 PF10363.4 EGC38984.1 - 0.079 12.8 0.0 14 5.6 0.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF2435) Ctr PF04145.10 EGC38984.1 - 3.5 7.6 5.4 9 6.3 0.0 2.7 2 0 0 2 2 2 0 Ctr copper transporter family Kei1 PF08552.6 EGC38984.1 - 5 6.7 6.2 8.6 5.9 0.5 2.5 2 0 0 2 2 2 0 Inositolphosphorylceramide synthase subunit Kei1 PRA1 PF03208.14 EGC38985.1 - 0.0083 15.4 2.2 0.016 14.5 1.5 1.4 1 0 0 1 1 1 1 PRA1 family protein RhodobacterPufX PF11511.3 EGC38985.1 - 0.21 11.0 1.1 0.49 9.8 0.8 1.6 1 0 0 1 1 1 0 Intrinsic membrane protein PufX SP_C-Propep PF08999.5 EGC38985.1 - 3.6 7.1 5.4 8.7 5.8 3.8 1.5 1 0 0 1 1 1 0 Surfactant protein C, N terminal propeptide GTP_EFTU PF00009.22 EGC38986.1 - 1.2e-58 197.6 0.1 1.7e-58 197.1 0.0 1.2 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGC38986.1 - 4.8e-34 116.4 0.1 2.3e-33 114.3 0.0 2.1 2 0 0 2 2 2 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGC38986.1 - 1.4e-16 60.3 0.4 3.5e-16 59.0 0.3 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC38986.1 - 2.3e-05 24.3 0.1 7.3e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGC38986.1 - 2.6e-05 23.7 0.5 7.9e-05 22.2 0.4 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Gtr1_RagA PF04670.7 EGC38986.1 - 0.0023 17.1 0.0 0.0049 16.0 0.0 1.5 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC38986.1 - 0.027 14.9 0.2 0.25 11.8 0.2 2.3 1 1 0 1 1 1 0 Miro-like protein Dynamin_N PF00350.18 EGC38986.1 - 0.11 12.2 0.2 8.8 6.1 0.1 2.4 1 1 0 2 2 2 0 Dynamin family FeoB_N PF02421.13 EGC38986.1 - 0.11 11.7 0.4 0.68 9.1 0.0 2.3 2 1 0 2 2 2 0 Ferrous iron transport protein B AMP-binding PF00501.23 EGC38987.1 - 1.2e-75 254.5 0.0 1.4e-75 254.2 0.0 1.1 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC38987.1 - 0.01 16.7 0.0 0.02 15.8 0.0 1.5 1 0 0 1 1 1 0 AMP-binding enzyme C-terminal domain PTR2 PF00854.16 EGC38988.1 - 1.3e-71 241.3 23.8 2.5e-60 204.2 8.8 3.1 1 1 2 3 3 3 2 POT family Herpes_LMP1 PF05297.6 EGC38988.1 - 9.9 4.9 8.2 0.93 8.3 0.3 2.3 1 1 0 2 2 2 0 Herpesvirus latent membrane protein 1 (LMP1) PTR2 PF00854.16 EGC38989.1 - 7.6e-72 242.1 26.3 4.3e-61 206.7 9.9 3.1 1 1 2 3 3 3 2 POT family AAA_12 PF13087.1 EGC38991.1 - 2.5e-22 79.2 2.3 2.5e-22 79.2 1.6 2.9 2 1 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EGC38991.1 - 1.2e-21 77.4 0.6 1.2e-21 77.4 0.4 1.9 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGC38991.1 - 1.4e-06 28.0 0.0 2.6e-06 27.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain UvrD_C PF13361.1 EGC38991.1 - 2.4e-06 27.2 7.2 0.0019 17.7 0.4 3.4 3 1 1 4 4 4 2 UvrD-like helicase C-terminal domain AAA_19 PF13245.1 EGC38991.1 - 3.9e-06 26.5 0.0 7.3e-06 25.6 0.0 1.3 1 0 0 1 1 1 1 Part of AAA domain CbiA PF01656.18 EGC38991.1 - 1.8e-05 24.2 1.1 0.00057 19.3 0.4 2.9 2 1 0 2 2 2 1 CobQ/CobB/MinD/ParA nucleotide binding domain SRP54 PF00448.17 EGC38991.1 - 0.0017 17.8 0.2 0.08 12.3 0.1 2.8 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_10 PF12846.2 EGC38991.1 - 0.022 14.1 0.9 0.062 12.7 0.6 1.8 1 1 0 1 1 1 0 AAA-like domain ArgK PF03308.11 EGC38991.1 - 0.032 13.0 0.0 0.072 11.8 0.0 1.5 1 0 0 1 1 1 0 ArgK protein AAA PF00004.24 EGC38991.1 - 0.036 14.2 2.0 5.9 7.1 0.0 2.9 3 0 0 3 3 2 0 ATPase family associated with various cellular activities (AAA) Rotamase PF00639.16 EGC38991.1 - 0.08 13.6 0.4 0.27 11.9 0.3 1.9 1 0 0 1 1 1 0 PPIC-type PPIASE domain AAA_22 PF13401.1 EGC38991.1 - 0.085 12.9 1.7 0.27 11.3 0.1 2.7 3 1 0 3 3 3 0 AAA domain AAA_17 PF13207.1 EGC38991.1 - 0.1 13.4 0.2 0.47 11.2 0.2 2.2 1 1 0 1 1 1 0 AAA domain GDPD_2 PF13653.1 EGC38991.1 - 0.15 12.2 0.0 0.36 11.0 0.0 1.6 1 0 0 1 1 1 0 Glycerophosphoryl diester phosphodiesterase family ResIII PF04851.10 EGC38991.1 - 0.23 11.2 11.1 0.16 11.8 1.5 3.3 1 1 0 2 2 2 0 Type III restriction enzyme, res subunit UvrD-helicase PF00580.16 EGC38991.1 - 1.7 7.8 15.4 26 3.9 9.9 3.0 1 1 0 1 1 1 0 UvrD/REP helicase N-terminal domain AAA_18 PF13238.1 EGC38991.1 - 5.5 7.2 9.3 29 4.9 4.2 3.3 2 1 0 2 2 2 0 AAA domain DUF3439 PF11921.3 EGC38992.1 - 0.4 10.4 4.7 0.81 9.4 3.3 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF3584 PF12128.3 EGC38992.1 - 6 4.0 49.3 7 3.8 34.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3584) Myotub-related PF06602.9 EGC38993.1 - 2.2e-118 395.0 0.0 2.2e-118 395.0 0.0 1.7 2 0 0 2 2 2 1 Myotubularin-like phosphatase domain Ank_2 PF12796.2 EGC38993.1 - 2.1e-31 108.0 0.2 1.1e-14 54.4 0.0 3.2 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC38993.1 - 2.1e-28 96.6 0.0 1.3e-07 31.0 0.0 5.8 5 0 0 5 5 5 5 Ankyrin repeat Ank_4 PF13637.1 EGC38993.1 - 1.2e-23 83.0 1.3 1.6e-08 34.8 0.0 5.1 2 1 2 4 4 4 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC38993.1 - 1.3e-22 77.5 0.9 0.00016 21.6 0.0 6.0 5 0 0 5 5 5 5 Ankyrin repeat Ank_5 PF13857.1 EGC38993.1 - 4e-21 74.5 9.4 3.3e-09 36.6 0.0 5.8 4 1 1 5 5 5 3 Ankyrin repeats (many copies) GRAM PF02893.15 EGC38993.1 - 0.0016 17.9 0.2 0.0051 16.3 0.1 1.8 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 EGC38993.1 - 0.023 14.9 0.0 0.061 13.5 0.0 1.6 1 0 0 1 1 1 0 Tyrosine phosphatase family F-box-like PF12937.2 EGC38994.1 - 0.00014 21.5 0.0 0.00022 20.8 0.0 1.3 1 0 0 1 1 1 1 F-box-like ThuA PF06283.6 EGC38994.1 - 0.005 16.5 0.1 0.011 15.5 0.0 1.6 2 0 0 2 2 2 1 Trehalose utilisation F-box PF00646.28 EGC38994.1 - 0.1 12.2 0.1 0.21 11.2 0.1 1.6 1 0 0 1 1 1 0 F-box domain Branch PF02485.16 EGC38995.1 - 1.8e-11 43.6 0.5 4.5e-11 42.3 0.3 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme WD40 PF00400.27 EGC38996.1 - 5.9e-55 181.3 44.7 2.1e-10 40.0 2.0 8.4 8 0 0 8 8 8 7 WD domain, G-beta repeat F-box-like PF12937.2 EGC38996.1 - 6.2e-10 38.6 0.2 1.3e-09 37.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like Nup160 PF11715.3 EGC38996.1 - 6.5e-10 37.7 17.3 0.11 10.5 0.0 6.2 2 2 4 6 6 6 6 Nucleoporin Nup120/160 F-box PF00646.28 EGC38996.1 - 1e-07 31.3 1.5 1.2e-07 31.1 0.1 2.0 2 0 0 2 2 2 1 F-box domain Sec63 PF02889.11 EGC38998.1 - 3.9e-190 630.7 6.9 2.7e-98 329.0 0.5 2.5 2 0 0 2 2 2 2 Sec63 Brl domain DEAD PF00270.24 EGC38998.1 - 8.5e-48 162.0 7.4 9.2e-26 90.3 0.1 4.6 5 0 0 5 5 5 2 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC38998.1 - 1.9e-12 46.8 0.0 1.7e-07 31.0 0.0 3.0 2 0 0 2 2 2 2 Helicase conserved C-terminal domain SMN PF06003.7 EGC38998.1 - 0.18 10.9 7.1 0.5 9.4 4.9 1.7 1 0 0 1 1 1 0 Survival motor neuron protein (SMN) RhoGEF PF00621.15 EGC39000.1 - 2.5e-51 174.1 8.9 2.3e-50 170.9 4.0 2.8 2 0 0 2 2 2 1 RhoGEF domain CH PF00307.26 EGC39000.1 - 7.1e-34 116.1 6.6 5e-12 45.8 0.1 4.1 3 0 0 3 3 3 3 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC39000.1 - 3.5e-11 42.6 4.3 0.0022 17.5 0.0 4.8 3 3 0 3 3 3 3 CAMSAP CH domain PH PF00169.24 EGC39000.1 - 6.8e-07 29.4 0.4 6.8e-07 29.4 0.3 3.5 4 0 0 4 4 4 1 PH domain CDC24 PF06395.6 EGC39000.1 - 1.3e-05 25.1 5.7 0.096 12.7 0.1 3.9 4 0 0 4 4 4 2 CDC24 Calponin Plant_zn_clust PF10533.4 EGC39000.1 - 0.048 13.3 0.1 0.14 11.7 0.1 1.8 1 0 0 1 1 1 0 Plant zinc cluster domain CRAL_TRIO_2 PF13716.1 EGC39001.1 - 1.1e-38 132.5 0.4 1.5e-38 132.0 0.3 1.2 1 0 0 1 1 1 1 Divergent CRAL/TRIO domain CRAL_TRIO PF00650.15 EGC39001.1 - 7.7e-07 28.7 0.2 4.7e-06 26.1 0.2 2.0 1 1 0 1 1 1 1 CRAL/TRIO domain SPC25 PF06703.6 EGC39002.1 - 7e-25 87.4 0.2 2.3e-13 50.0 0.0 2.0 1 1 1 2 2 2 2 Microsomal signal peptidase 25 kDa subunit (SPC25) Paf1 PF03985.8 EGC39003.1 - 6.4e-48 163.5 13.0 6.4e-48 163.5 9.0 2.1 2 0 0 2 2 2 1 Paf1 PPI_Ypi1 PF07491.6 EGC39004.1 - 8.3e-24 82.9 1.1 8.3e-24 82.9 0.8 2.1 2 1 0 2 2 2 1 Protein phosphatase inhibitor Ras PF00071.17 EGC39005.1 - 5.2e-61 204.7 0.8 6.1e-61 204.5 0.6 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39005.1 - 5e-21 75.4 0.0 8.6e-21 74.6 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39005.1 - 3.6e-14 52.3 0.2 4.6e-14 52.0 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC39005.1 - 6.6e-08 32.5 0.1 1e-07 31.8 0.1 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC39005.1 - 2.4e-06 27.0 0.2 7.6e-06 25.4 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC39005.1 - 6.2e-05 22.2 0.2 8.9e-05 21.7 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region AAA_22 PF13401.1 EGC39005.1 - 0.00026 21.1 0.1 0.0012 18.9 0.1 2.0 2 1 0 2 2 2 1 AAA domain PduV-EutP PF10662.4 EGC39005.1 - 0.00051 19.5 0.0 0.0012 18.2 0.0 1.7 1 1 1 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC39005.1 - 0.00059 19.1 0.1 0.00083 18.6 0.1 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_15 PF13175.1 EGC39005.1 - 0.001 18.1 0.0 0.0015 17.6 0.0 1.3 1 1 0 1 1 1 1 AAA ATPase domain FeoB_N PF02421.13 EGC39005.1 - 0.0023 17.2 0.5 0.023 13.9 0.3 2.0 1 1 0 1 1 1 1 Ferrous iron transport protein B DUF258 PF03193.11 EGC39005.1 - 0.0033 16.6 0.1 0.0067 15.6 0.1 1.5 1 1 0 1 1 1 1 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGC39005.1 - 0.0074 16.1 0.1 0.018 14.9 0.1 1.6 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC39005.1 - 0.0077 16.2 0.3 0.018 15.0 0.2 1.7 1 1 0 1 1 1 1 AAA ATPase domain AAA_32 PF13654.1 EGC39005.1 - 0.011 14.4 0.2 0.3 9.6 0.0 2.0 1 1 1 2 2 2 0 AAA domain ABC_tran PF00005.22 EGC39005.1 - 0.013 15.7 0.2 0.026 14.8 0.2 1.7 1 1 0 1 1 1 0 ABC transporter AAA_28 PF13521.1 EGC39005.1 - 0.042 13.8 0.6 0.16 11.9 0.4 1.9 1 1 0 1 1 1 0 AAA domain Fer2_3 PF13085.1 EGC39006.1 - 2.9e-33 113.9 0.0 5.3e-33 113.1 0.0 1.4 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain Fer4_17 PF13534.1 EGC39006.1 - 5.5e-10 39.4 4.0 5.5e-10 39.4 2.8 2.0 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_8 PF13183.1 EGC39006.1 - 8.8e-10 38.4 3.2 8.8e-10 38.4 2.2 1.9 2 0 0 2 2 2 1 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGC39006.1 - 0.00012 21.7 5.3 0.00012 21.7 3.7 2.4 2 1 0 2 2 2 1 4Fe-4S dicluster domain Fer4_9 PF13187.1 EGC39006.1 - 0.0002 21.5 7.9 0.053 13.7 0.2 3.2 3 1 0 3 3 3 2 4Fe-4S dicluster domain Fer4_18 PF13746.1 EGC39006.1 - 0.0013 19.1 7.1 1.6 9.2 0.0 2.9 2 1 0 2 2 2 2 4Fe-4S dicluster domain Fer2 PF00111.22 EGC39006.1 - 0.0021 17.7 4.6 0.0054 16.4 0.3 2.4 2 0 0 2 2 2 1 2Fe-2S iron-sulfur cluster binding domain Fer4_16 PF13484.1 EGC39006.1 - 0.42 11.3 8.3 4.4 8.1 0.8 3.1 3 0 0 3 3 3 0 4Fe-4S double cluster binding domain Fer4_7 PF12838.2 EGC39006.1 - 0.97 9.8 15.1 0.42 11.0 7.0 2.7 1 1 1 2 2 2 0 4Fe-4S dicluster domain EXS PF03124.9 EGC39008.1 - 0.0011 18.1 0.6 0.0014 17.7 0.4 1.1 1 0 0 1 1 1 1 EXS family PalH PF08733.5 EGC39008.1 - 0.043 12.6 1.7 0.053 12.3 1.0 1.2 1 1 0 1 1 1 0 PalH/RIM21 SdpI PF13630.1 EGC39008.1 - 3.2 7.5 6.8 5.1 6.8 4.7 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF810 PF05664.6 EGC39009.1 - 2.2e-16 59.3 7.2 8.7e-16 57.3 5.0 1.8 1 1 0 1 1 1 1 Protein of unknown function (DUF810) His_kinase PF06580.8 EGC39009.1 - 8.6 6.3 11.4 5.2 7.0 0.0 4.7 5 0 0 5 5 5 0 Histidine kinase Steroid_dh PF02544.11 EGC39010.1 - 7.2e-43 145.9 1.1 1.4e-42 145.0 0.8 1.4 1 0 0 1 1 1 1 3-oxo-5-alpha-steroid 4-dehydrogenase PEMT PF04191.8 EGC39010.1 - 0.0011 18.9 0.2 0.0011 18.9 0.2 2.0 2 0 0 2 2 2 1 Phospholipid methyltransferase DUF1295 PF06966.7 EGC39010.1 - 0.0063 15.8 0.5 0.0095 15.2 0.3 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) DUF2701 PF10857.3 EGC39011.1 - 0.052 13.3 2.0 0.052 13.3 1.4 2.7 2 1 2 4 4 4 0 Protein of unknown function (DUF2701) Sel1 PF08238.7 EGC39012.1 - 1.8e-37 126.9 29.4 1.4e-05 25.5 0.2 12.1 13 0 0 13 13 13 8 Sel1 repeat TPR_7 PF13176.1 EGC39012.1 - 0.032 14.0 0.8 1.7 8.6 0.0 3.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC39012.1 - 0.037 14.7 5.2 23 5.8 0.1 4.9 4 0 0 4 4 4 0 Tetratricopeptide repeat Conotoxin PF02950.12 EGC39012.1 - 0.061 14.1 0.1 0.061 14.1 0.1 3.1 3 0 0 3 3 3 0 Conotoxin GRP PF07172.6 EGC39012.1 - 0.26 11.7 0.0 0.26 11.7 0.0 3.3 3 0 0 3 3 3 0 Glycine rich protein family Sel1 PF08238.7 EGC39013.1 - 8.4e-47 156.5 32.1 1.5e-05 25.4 0.0 12.3 13 0 0 13 13 13 9 Sel1 repeat Shisa PF13908.1 EGC39013.1 - 0.089 12.9 5.8 2.8 8.0 0.0 2.6 2 1 0 2 2 2 0 Wnt and FGF inhibitory regulator TPR_11 PF13414.1 EGC39013.1 - 0.3 10.7 20.3 0.4 10.3 0.1 6.2 5 1 2 7 7 7 0 TPR repeat EphA2_TM PF14575.1 EGC39013.1 - 0.46 10.8 2.0 13 6.2 0.5 3.4 3 1 0 3 3 3 0 Ephrin type-A receptor 2 transmembrane domain TPR_6 PF13174.1 EGC39013.1 - 0.96 10.0 10.7 53 4.5 0.3 5.9 6 0 0 6 6 6 0 Tetratricopeptide repeat Peptidase_S49_N PF08496.5 EGC39013.1 - 4.8 6.9 6.1 7.3 6.3 3.6 1.8 1 1 0 1 1 1 0 Peptidase family S49 N-terminal DUF3139 PF11337.3 EGC39013.1 - 5.1 7.4 9.7 0.49 10.7 2.1 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) Zip PF02535.17 EGC39013.1 - 9.9 5.0 5.1 54 2.6 0.0 2.5 2 1 0 2 2 2 0 ZIP Zinc transporter Mago_nashi PF02792.9 EGC39015.1 - 7.8e-75 249.3 1.1 7.8e-75 249.3 0.8 1.6 2 0 0 2 2 2 1 Mago nashi protein DUF3506 PF12014.3 EGC39015.1 - 0.014 15.2 0.1 0.022 14.5 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF3506) PWI PF01480.12 EGC39016.1 - 1.5e-13 50.5 2.6 1.5e-13 50.5 1.8 3.2 2 0 0 2 2 2 1 PWI domain RRM_1 PF00076.17 EGC39016.1 - 3.3e-06 26.6 0.0 8.1e-06 25.3 0.0 1.7 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC39016.1 - 0.013 15.4 0.0 0.032 14.2 0.0 1.6 1 0 0 1 1 1 0 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) DUF1777 PF08648.7 EGC39016.1 - 0.11 12.2 33.7 0.35 10.5 22.3 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1777) Metallophos PF00149.23 EGC39017.1 - 1e-15 57.6 1.7 2e-15 56.6 1.2 1.5 1 0 0 1 1 1 1 Calcineurin-like phosphoesterase FHA PF00498.21 EGC39018.1 - 2.1e-19 69.4 0.0 5.7e-19 67.9 0.0 1.8 1 0 0 1 1 1 1 FHA domain ALAD PF00490.16 EGC39019.1 - 9.5e-121 402.6 0.0 1.1e-120 402.4 0.0 1.0 1 0 0 1 1 1 1 Delta-aminolevulinic acid dehydratase Ras PF00071.17 EGC39020.1 - 7.5e-41 139.2 0.0 9.8e-41 138.8 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39020.1 - 1.1e-16 61.4 0.0 1.7e-16 60.7 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39020.1 - 2.2e-12 46.5 0.0 3e-12 46.1 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39020.1 - 4.7e-07 29.1 0.0 7.7e-07 28.4 0.0 1.3 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC39020.1 - 2.4e-06 26.8 0.0 3.6e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit GTP_EFTU PF00009.22 EGC39020.1 - 6.4e-06 25.7 0.0 0.0001 21.7 0.0 2.2 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC39020.1 - 0.00037 20.4 0.0 0.00072 19.4 0.0 1.5 1 0 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC39020.1 - 0.00077 18.2 0.5 0.1 11.2 0.0 2.1 2 0 0 2 2 2 2 G-protein alpha subunit PduV-EutP PF10662.4 EGC39020.1 - 0.068 12.6 0.0 0.78 9.2 0.0 2.1 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation EBP PF05241.7 EGC39021.1 - 1.8e-45 154.3 11.1 2.1e-45 154.1 7.7 1.0 1 0 0 1 1 1 1 Emopamil binding protein DUF4293 PF14126.1 EGC39021.1 - 0.62 9.9 9.3 1.8 8.5 0.6 2.3 1 1 1 2 2 2 0 Domain of unknown function (DUF4293) Corona_M PF01635.13 EGC39021.1 - 5.8 5.7 9.3 0.39 9.6 0.2 2.4 3 0 0 3 3 3 0 Coronavirus M matrix/glycoprotein RRM_1 PF00076.17 EGC39022.1 - 1.2e-13 50.4 0.2 3.2e-06 26.6 0.0 2.6 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC39022.1 - 8.7e-10 38.4 0.0 0.0016 18.4 0.0 2.4 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC39022.1 - 2.6e-09 36.7 0.0 0.00023 20.9 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) CTD_bind PF04818.8 EGC39022.1 - 6.1e-05 23.1 0.1 0.00029 21.0 0.0 2.1 2 0 0 2 2 2 1 RNA polymerase II-binding domain. HATPase_c PF02518.21 EGC39023.1 - 2.1e-23 82.1 0.2 5.1e-23 80.9 0.1 1.7 1 0 0 1 1 1 1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase Response_reg PF00072.19 EGC39023.1 - 7e-16 58.2 0.3 3.1e-15 56.1 0.1 2.3 2 0 0 2 2 2 1 Response regulator receiver domain HisKA PF00512.20 EGC39023.1 - 1.3e-15 57.1 0.0 2.8e-15 56.0 0.0 1.6 1 0 0 1 1 1 1 His Kinase A (phospho-acceptor) domain PAS_8 PF13188.1 EGC39023.1 - 5.5e-06 26.0 0.0 1.5e-05 24.7 0.0 1.7 1 0 0 1 1 1 1 PAS domain PAS PF00989.19 EGC39023.1 - 0.017 14.9 0.0 0.052 13.3 0.0 1.9 1 0 0 1 1 1 0 PAS fold DSPc PF00782.15 EGC39024.1 - 1.2e-31 109.0 0.1 1.6e-31 108.6 0.1 1.1 1 0 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase PF00102.22 EGC39024.1 - 7.4e-06 25.4 0.0 9.5e-06 25.1 0.0 1.2 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase2 PF03162.8 EGC39024.1 - 0.0028 17.0 0.1 0.0047 16.2 0.0 1.3 1 0 0 1 1 1 1 Tyrosine phosphatase family Init_tRNA_PT PF04179.7 EGC39024.1 - 0.0033 16.3 0.0 0.0034 16.3 0.0 1.1 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Rad52_Rad22 PF04098.10 EGC39025.1 - 4.7e-47 159.5 0.0 7.1e-47 158.9 0.0 1.2 1 0 0 1 1 1 1 Rad52/22 family double-strand break repair protein DUF605 PF04652.11 EGC39025.1 - 0.057 12.8 19.8 0.072 12.4 13.7 1.1 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGC39025.1 - 3 5.9 16.8 3.6 5.7 11.7 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Cofilin_ADF PF00241.15 EGC39026.1 - 0.002 18.0 0.0 0.0021 17.9 0.0 1.1 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Filamin PF00630.14 EGC39028.1 - 1.7e-130 426.5 15.7 2.6e-23 82.4 0.2 6.2 6 0 0 6 6 6 6 Filamin/ABP280 repeat CH PF00307.26 EGC39028.1 - 2.2e-30 104.8 0.2 9.1e-16 57.8 0.1 2.3 2 0 0 2 2 2 2 Calponin homology (CH) domain Big_1 PF02369.11 EGC39028.1 - 7.2e-13 48.2 5.6 0.14 12.0 0.0 6.8 6 1 0 6 6 6 4 Bacterial Ig-like domain (group 1) Y_Y_Y PF07495.8 EGC39028.1 - 9.5e-09 34.8 3.2 0.012 15.3 0.0 6.4 7 0 0 7 7 7 2 Y_Y_Y domain Big_3_4 PF13754.1 EGC39028.1 - 1.7e-08 34.6 21.4 0.0093 16.2 0.1 7.7 7 1 1 8 8 7 2 Bacterial Ig-like domain (group 3) CAMSAP_CH PF11971.3 EGC39028.1 - 1.6e-07 30.8 0.1 0.00028 20.4 0.0 2.5 2 0 0 2 2 2 2 CAMSAP CH domain YtkA PF13115.1 EGC39028.1 - 8.5e-05 22.8 9.7 2.7 8.3 0.0 6.2 6 0 0 6 6 6 2 YtkA-like Neurexophilin PF06312.7 EGC39028.1 - 0.0044 16.2 0.4 17 4.5 0.0 4.8 6 0 0 6 6 6 0 Neurexophilin PKD PF00801.15 EGC39028.1 - 0.0082 15.8 0.5 0.32 10.7 0.0 3.6 4 0 0 4 4 4 1 PKD domain DUF1214 PF06742.6 EGC39028.1 - 0.013 15.9 8.4 37 4.8 0.0 5.6 5 1 0 5 5 5 0 Protein of unknown function (DUF1214) Big_3 PF07523.7 EGC39028.1 - 0.031 14.3 12.2 2.5 8.2 0.6 4.9 5 0 0 5 5 4 0 Bacterial Ig-like domain (group 3) FixH PF05751.6 EGC39028.1 - 0.16 11.8 0.0 54 3.5 0.0 4.2 5 0 0 5 5 5 0 FixH DUF1541 PF07563.6 EGC39028.1 - 10 5.9 7.6 29 4.4 0.1 4.0 5 0 0 5 5 4 0 Protein of unknown function (DUF1541) Spore_III_AE PF09546.5 EGC39029.1 - 0.048 12.6 2.4 0.057 12.3 1.6 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) DUF1673 PF07895.6 EGC39029.1 - 0.18 11.2 9.1 0.16 11.4 5.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1673) zf-RVT PF13966.1 EGC39030.1 - 1.2e-07 31.9 1.0 2.7e-07 30.8 0.7 1.7 1 1 0 1 1 1 1 zinc-binding in reverse transcriptase FNIP PF05725.7 EGC39031.1 - 2e-10 40.4 1.6 2.9e-06 27.1 0.1 3.3 2 1 1 3 3 3 2 FNIP Repeat zf-RVT PF13966.1 EGC39031.1 - 9.7e-07 29.0 1.3 3.1e-06 27.4 0.2 2.2 2 0 0 2 2 2 1 zinc-binding in reverse transcriptase FNIP PF05725.7 EGC39032.1 - 4.5e-105 343.4 58.0 8.3e-15 54.4 0.2 9.2 4 2 5 11 11 11 11 FNIP Repeat FAST_1 PF06743.10 EGC39032.1 - 0.028 14.1 0.5 29 4.4 0.0 4.3 3 1 1 4 4 4 0 FAST kinase-like protein, subdomain 1 FNIP PF05725.7 EGC39033.1 - 1.7e-54 181.4 27.4 3.2e-14 52.5 0.2 5.5 3 2 3 6 6 6 6 FNIP Repeat Jacalin PF01419.12 EGC39033.1 - 0.8 9.5 3.8 3.1 7.6 0.2 2.8 1 1 3 4 4 4 0 Jacalin-like lectin domain FNIP PF05725.7 EGC39034.1 - 2.3e-136 443.5 85.1 6.1e-16 58.0 1.1 10.2 3 2 9 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC39034.1 - 0.018 15.0 28.9 2.6 8.0 0.0 9.4 4 2 7 11 11 11 0 Protein of unknown function (DUF1769) Bclx_interact PF08945.5 EGC39034.1 - 0.094 12.2 2.4 22 4.6 0.0 3.8 4 0 0 4 4 4 0 Bcl-x interacting, BH3 domain DUF3215 PF11503.3 EGC39034.1 - 0.16 11.6 0.1 20 4.8 0.0 4.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3215) ThiF PF00899.16 EGC39035.1 - 9.4e-55 184.1 0.5 7.3e-34 116.5 0.0 3.0 3 0 0 3 3 3 2 ThiF family UBA_e1_C PF09358.5 EGC39035.1 - 2.7e-43 147.0 1.1 4.8e-43 146.2 0.2 1.9 2 0 0 2 2 2 1 Ubiquitin-activating enzyme e1 C-terminal domain UBACT PF02134.16 EGC39035.1 - 6.9e-41 137.6 10.6 8e-27 92.6 0.8 3.7 3 0 0 3 3 3 2 Repeat in ubiquitin-activating (UBA) protein UBA_e1_thiolCys PF10585.4 EGC39035.1 - 1.6e-25 88.2 1.9 2e-21 75.1 0.1 2.5 2 0 0 2 2 2 2 Ubiquitin-activating enzyme active site E2_bind PF08825.5 EGC39035.1 - 0.078 12.7 2.1 4.4 7.1 1.0 2.7 2 0 0 2 2 2 0 E2 binding domain Peptidase_M48 PF01435.13 EGC39036.1 - 6.6e-30 104.3 0.1 1.3e-29 103.3 0.1 1.5 1 0 0 1 1 1 1 Peptidase family M48 FtsX PF02687.16 EGC39036.1 - 0.023 14.4 2.1 0.023 14.4 1.4 3.1 5 0 0 5 5 5 0 FtsX-like permease family DCX PF03607.12 EGC39036.1 - 0.054 13.1 0.0 0.3 10.6 0.0 2.2 2 0 0 2 2 2 0 Doublecortin DUF1279 PF06916.8 EGC39036.1 - 0.058 13.6 0.6 0.058 13.6 0.4 3.4 3 1 0 3 3 3 0 Protein of unknown function (DUF1279) Peptidase_M56 PF05569.6 EGC39036.1 - 0.22 10.4 9.6 0.035 13.0 2.1 2.8 3 1 0 3 3 3 0 BlaR1 peptidase M56 Coiled PF05710.7 EGC39037.1 - 0.46 10.9 10.9 0.6 10.6 7.5 1.2 1 0 0 1 1 1 0 Coiled coil Ion_trans PF00520.26 EGC39038.1 - 0.0031 16.7 0.1 0.0037 16.5 0.0 1.1 1 0 0 1 1 1 1 Ion transport protein AIF_C PF14721.1 EGC39038.1 - 1.2 9.4 5.4 6.8 6.9 3.4 2.2 2 0 0 2 2 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term PLDc_N PF13396.1 EGC39038.1 - 2.5 7.8 5.2 3.6 7.3 3.6 1.2 1 0 0 1 1 1 0 Phospholipase_D-nuclease N-terminal Pyrophosphatase PF00719.14 EGC39040.1 - 0.058 12.8 0.0 0.082 12.3 0.0 1.2 1 0 0 1 1 1 0 Inorganic pyrophosphatase 7TMR-DISM_7TM PF07695.6 EGC39041.1 - 0.0029 17.2 4.0 0.0043 16.7 2.8 1.2 1 0 0 1 1 1 1 7TM diverse intracellular signalling PRY PF13765.1 EGC39041.1 - 0.017 14.6 1.2 1.5 8.4 0.0 2.9 3 0 0 3 3 3 0 SPRY-associated domain MARVEL PF01284.18 EGC39041.1 - 0.065 13.0 0.9 0.85 9.4 0.6 2.2 1 1 0 1 1 1 0 Membrane-associating domain DUF1275 PF06912.6 EGC39041.1 - 0.092 11.9 3.0 0.14 11.3 1.0 1.8 1 1 1 2 2 2 0 Protein of unknown function (DUF1275) DUF4401 PF14351.1 EGC39041.1 - 0.11 11.4 5.5 0.29 10.0 3.5 1.7 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) YfhO PF09586.5 EGC39041.1 - 0.4 8.6 3.3 0.94 7.4 2.3 1.6 1 1 0 1 1 1 0 Bacterial membrane protein YfhO DUF202 PF02656.10 EGC39041.1 - 5.4 7.3 7.6 3.3e+02 1.5 5.2 2.6 1 1 0 1 1 1 0 Domain of unknown function (DUF202) OppC_N PF12911.2 EGC39041.1 - 7 6.1 8.5 14 5.1 0.2 3.6 2 1 1 3 3 3 0 N-terminal TM domain of oligopeptide transport permease C M_domain PF12938.2 EGC39043.1 - 0.13 12.0 0.6 0.16 11.7 0.4 1.1 1 0 0 1 1 1 0 M domain of GW182 PIP5K PF01504.13 EGC39045.1 - 4.4e-62 209.4 5.3 4.4e-62 209.4 3.7 2.6 2 1 0 2 2 2 1 Phosphatidylinositol-4-phosphate 5-Kinase Tetraspannin PF00335.15 EGC39045.1 - 1.8 7.7 7.8 7 5.8 5.4 2.1 1 1 0 1 1 1 0 Tetraspanin family Kinesin PF00225.18 EGC39046.1 - 1.4e-31 109.4 0.0 1.4e-31 109.4 0.0 2.0 3 0 0 3 3 3 1 Kinesin motor domain BRCT PF00533.21 EGC39047.1 - 3.3e-12 46.3 1.0 8.4e-12 45.0 0.7 1.7 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC39047.1 - 0.0017 18.2 0.1 0.003 17.3 0.1 1.4 1 0 0 1 1 1 1 twin BRCT domain DivIC PF04977.10 EGC39047.1 - 8.7 5.9 9.8 0.11 11.9 1.1 2.1 2 0 0 2 2 2 0 Septum formation initiator Kinesin PF00225.18 EGC39048.1 - 1.7e-85 286.7 1.9 1.7e-85 286.7 1.3 3.6 4 1 0 4 4 4 1 Kinesin motor domain Myosin_tail_1 PF01576.14 EGC39048.1 - 1.7e-05 22.8 63.6 1.7e-05 22.8 44.1 2.1 1 1 1 2 2 2 1 Myosin tail FNIP PF05725.7 EGC39049.1 - 3.8e-40 135.5 22.9 5.1e-13 48.7 0.1 6.6 4 1 3 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC39049.1 - 0.0019 18.1 2.3 1.9 8.4 0.0 4.8 3 1 1 5 5 5 1 Protein of unknown function (DUF1769) Copine PF07002.11 EGC39050.1 - 1.4e-16 60.5 2.8 2.5e-15 56.4 1.9 2.3 1 1 0 1 1 1 1 Copine C2 PF00168.25 EGC39050.1 - 4.9e-10 39.1 0.1 0.00012 21.8 0.0 2.4 2 0 0 2 2 2 2 C2 domain vWA-TerF-like PF10138.4 EGC39050.1 - 0.082 12.7 0.0 0.26 11.0 0.0 1.8 1 1 0 1 1 1 0 vWA found in TerF C terminus Adaptin_N PF01602.15 EGC39052.1 - 3.6e-113 378.6 18.9 3.6e-113 378.6 13.1 1.5 2 0 0 2 2 2 1 Adaptin N terminal region COP-gamma_platf PF08752.5 EGC39052.1 - 8.1e-58 194.5 0.1 1.9e-57 193.3 0.1 1.6 1 0 0 1 1 1 1 Coatomer gamma subunit appendage platform subdomain HEAT_2 PF13646.1 EGC39052.1 - 1.7e-12 47.4 1.5 0.034 14.4 0.0 5.7 2 1 1 5 5 5 4 HEAT repeats Cnd1 PF12717.2 EGC39052.1 - 3.1e-08 33.6 14.1 0.0022 17.8 1.4 4.3 4 0 0 4 4 4 3 non-SMC mitotic condensation complex subunit 1 HEAT PF02985.17 EGC39052.1 - 1.2e-05 25.0 6.5 0.41 10.8 0.0 6.3 7 0 0 7 7 7 2 HEAT repeat HEAT_EZ PF13513.1 EGC39052.1 - 0.00032 21.0 0.9 0.051 14.0 0.1 4.1 3 1 2 5 5 5 1 HEAT-like repeat DNA_alkylation PF08713.6 EGC39052.1 - 0.0043 16.6 0.1 0.14 11.6 0.0 2.6 2 0 0 2 2 2 1 DNA alkylation repair enzyme KaiC PF06745.8 EGC39052.1 - 0.046 12.8 1.2 0.11 11.6 0.1 2.0 2 0 0 2 2 2 0 KaiC Methyltransf_2 PF00891.13 EGC39053.1 - 7.8e-48 162.7 0.0 9.7e-48 162.4 0.0 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_23 PF13489.1 EGC39053.1 - 0.0005 19.8 0.0 0.00081 19.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39053.1 - 0.015 15.8 0.0 0.027 15.0 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain TrmB PF01978.14 EGC39053.1 - 0.052 13.2 0.0 0.1 12.3 0.0 1.4 1 0 0 1 1 1 0 Sugar-specific transcriptional regulator TrmB Toxin_51 PF15531.1 EGC39053.1 - 0.098 12.4 0.0 0.17 11.7 0.0 1.3 1 0 0 1 1 1 0 Putative toxin 51 PWWP PF00855.12 EGC39054.1 - 2.3e-14 53.3 0.1 2.3e-14 53.3 0.1 3.7 2 1 0 2 2 2 1 PWWP domain SDA1 PF05285.7 EGC39054.1 - 0.011 15.0 1.3 0.011 15.0 0.9 2.2 1 1 0 2 2 2 0 SDA1 NADH-G_4Fe-4S_3 PF10588.4 EGC39054.1 - 8.5 5.6 6.5 15 4.8 4.5 1.4 1 0 0 1 1 1 0 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region FA_desaturase PF00487.19 EGC39055.1 - 5.3e-17 62.1 6.1 5.3e-17 62.1 4.3 3.5 3 1 0 3 3 3 2 Fatty acid desaturase Cyt-b5 PF00173.23 EGC39055.1 - 9.1e-14 51.0 0.1 2.6e-13 49.5 0.0 1.8 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MerC PF03203.9 EGC39055.1 - 0.07 13.4 0.1 0.07 13.4 0.1 2.4 3 1 0 3 3 3 0 MerC mercury resistance protein Fip1 PF05182.8 EGC39056.1 - 3.7e-24 83.7 2.1 7.1e-24 82.8 1.5 1.5 1 0 0 1 1 1 1 Fip1 motif TFIIF_alpha PF05793.7 EGC39056.1 - 2.4e-05 22.9 8.3 2.4e-05 22.9 5.8 2.3 1 1 1 2 2 2 1 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Med15 PF09606.5 EGC39056.1 - 0.13 10.4 26.9 0.17 10.0 18.6 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal Defensin_beta PF00711.14 EGC39057.1 - 0.12 12.2 3.3 0.36 10.7 2.3 1.9 1 0 0 1 1 1 0 Beta defensin DUF3430 PF11912.3 EGC39057.1 - 0.39 10.5 23.3 3.5 7.3 16.2 2.5 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) LIM PF00412.17 EGC39058.1 - 7e-58 192.5 45.3 2.5e-16 59.4 3.0 4.2 4 0 0 4 4 4 4 LIM domain PAP_assoc PF03828.14 EGC39059.1 - 3.1e-08 33.4 0.2 3.1e-08 33.4 0.1 3.0 2 1 0 2 2 2 1 Cid1 family poly A polymerase NTP_transf_2 PF01909.18 EGC39059.1 - 5.3e-08 33.0 0.0 1.3e-07 31.8 0.0 1.6 1 0 0 1 1 1 1 Nucleotidyltransferase domain Big_2 PF02368.13 EGC39060.1 - 1.3 8.9 4.5 18 5.2 0.7 3.4 4 0 0 4 4 4 0 Bacterial Ig-like domain (group 2) VASP_tetra PF08776.6 EGC39063.1 - 0.62 9.4 3.8 1.6 8.1 1.0 2.4 2 0 0 2 2 2 0 VASP tetramerisation domain G-gamma PF00631.17 EGC39064.1 - 7.5e-19 67.2 0.2 9e-19 66.9 0.1 1.0 1 0 0 1 1 1 1 GGL domain RNA_pol_Rpb1_1 PF04997.7 EGC39064.1 - 0.0068 15.7 0.0 0.0076 15.5 0.0 1.0 1 0 0 1 1 1 1 RNA polymerase Rpb1, domain 1 F_actin_bind PF08919.5 EGC39064.1 - 0.042 13.5 0.0 0.053 13.2 0.0 1.1 1 0 0 1 1 1 0 F-actin binding NEMO PF11577.3 EGC39064.1 - 0.064 13.0 0.3 0.1 12.3 0.2 1.2 1 0 0 1 1 1 0 NF-kappa-B essential modulator NEMO Cast PF10174.4 EGC39064.1 - 0.14 10.2 0.8 0.16 10.0 0.5 1.0 1 0 0 1 1 1 0 RIM-binding protein of the cytomatrix active zone Mto2_bdg PF12808.2 EGC39064.1 - 0.16 12.1 1.1 0.23 11.6 0.7 1.2 1 0 0 1 1 1 0 Micro-tubular organiser Mto1 C-term Mto2-binding region THOC7 PF05615.8 EGC39064.1 - 0.21 11.8 1.5 0.27 11.4 1.1 1.1 1 0 0 1 1 1 0 Tho complex subunit 7 HALZ PF02183.13 EGC39064.1 - 1.9 8.2 5.3 0.32 10.7 1.3 1.6 2 0 0 2 2 2 0 Homeobox associated leucine zipper Rad9 PF04139.8 EGC39065.1 - 1.7e-70 237.0 2.7 1.7e-70 237.0 1.9 1.9 2 0 0 2 2 2 1 Rad9 Rad1 PF02144.11 EGC39065.1 - 4.9e-05 22.2 6.0 4.9e-05 22.2 4.2 2.8 2 1 0 2 2 2 1 Repair protein Rad1/Rec1/Rad17 RXT2_N PF08595.6 EGC39066.1 - 0.031 14.0 14.3 0.28 10.9 1.8 2.7 2 0 0 2 2 2 0 RXT2-like, N-terminal Nucleoplasmin PF03066.10 EGC39066.1 - 0.29 10.6 7.1 0.023 14.2 1.3 1.8 2 0 0 2 2 2 0 Nucleoplasmin Secretin_N_2 PF07655.8 EGC39066.1 - 3.2 8.1 21.6 0.44 10.9 11.2 2.1 2 0 0 2 2 2 0 Secretin N-terminal domain NOA36 PF06524.7 EGC39066.1 - 8.8 5.4 17.3 0.53 9.4 4.4 2.2 2 0 0 2 2 2 0 NOA36 protein Cofilin_ADF PF00241.15 EGC39067.1 - 1.4e-08 34.6 0.0 1.5e-08 34.5 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein Rhabdo_ncap PF00945.13 EGC39067.1 - 0.11 11.0 0.0 0.15 10.6 0.0 1.1 1 0 0 1 1 1 0 Rhabdovirus nucleocapsid protein Cofilin_ADF PF00241.15 EGC39068.1 - 2.5e-21 75.8 0.0 6.1e-10 39.0 0.0 2.1 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Phospholip_B PF04916.8 EGC39069.1 - 6.2e-116 387.7 11.8 7.4e-116 387.4 8.2 1.0 1 0 0 1 1 1 1 Phospholipase B DUF4602 PF15375.1 EGC39070.1 - 0.068 13.2 12.6 0.11 12.5 8.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4602) Ferritin PF00210.19 EGC39070.1 - 0.57 9.9 2.9 5.6 6.7 0.5 2.1 1 1 1 2 2 2 0 Ferritin-like domain Fig1 PF12351.3 EGC39072.1 - 0.055 13.3 0.4 0.13 12.1 0.3 1.7 1 0 0 1 1 1 0 Ca2+ regulator and membrane fusion protein Fig1 CcmD PF04995.9 EGC39072.1 - 0.23 11.2 1.0 2.2 8.0 1.3 2.1 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) ABC_membrane PF00664.18 EGC39074.1 - 1.2e-62 211.8 35.6 6.8e-33 114.2 11.5 2.3 2 0 0 2 2 2 2 ABC transporter transmembrane region ABC_tran PF00005.22 EGC39074.1 - 1.9e-52 177.1 0.3 1e-30 106.8 0.1 2.8 2 0 0 2 2 2 2 ABC transporter SMC_N PF02463.14 EGC39074.1 - 7e-13 48.3 4.0 0.008 15.4 0.0 4.3 2 2 1 3 3 3 3 RecF/RecN/SMC N terminal domain MMR_HSR1 PF01926.18 EGC39074.1 - 1.1e-06 28.5 0.0 0.017 15.0 0.0 2.9 2 0 0 2 2 2 2 50S ribosome-binding GTPase AAA_29 PF13555.1 EGC39074.1 - 3.9e-06 26.2 5.5 0.0066 15.9 0.0 3.1 3 0 0 3 3 2 2 P-loop containing region of AAA domain DUF258 PF03193.11 EGC39074.1 - 8.2e-06 25.1 0.5 0.0007 18.8 0.1 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Miro PF08477.8 EGC39074.1 - 4.6e-05 23.9 0.1 0.22 11.9 0.0 2.7 2 0 0 2 2 2 2 Miro-like protein T2SE PF00437.15 EGC39074.1 - 5.2e-05 22.2 0.0 0.067 12.0 0.0 2.3 2 0 0 2 2 2 2 Type II/IV secretion system protein AAA_17 PF13207.1 EGC39074.1 - 5.9e-05 23.8 0.1 0.22 12.3 0.0 3.0 2 0 0 2 2 2 2 AAA domain Dynamin_N PF00350.18 EGC39074.1 - 0.00013 21.7 2.8 0.003 17.4 0.2 2.9 2 0 0 2 2 2 1 Dynamin family Zeta_toxin PF06414.7 EGC39074.1 - 0.00017 20.7 0.1 0.11 11.6 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin AAA_10 PF12846.2 EGC39074.1 - 0.00023 20.6 2.9 0.055 12.9 0.1 3.1 2 1 0 3 3 3 1 AAA-like domain AAA_16 PF13191.1 EGC39074.1 - 0.00066 19.7 1.6 0.77 9.7 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGC39074.1 - 0.0016 17.9 0.2 1.2 8.6 0.0 2.3 2 0 0 2 2 2 2 FtsK/SpoIIIE family TrwB_AAD_bind PF10412.4 EGC39074.1 - 0.004 15.8 0.8 1.1 7.8 0.0 2.2 2 0 0 2 2 2 2 Type IV secretion-system coupling protein DNA-binding domain AAA_22 PF13401.1 EGC39074.1 - 0.0068 16.5 0.8 1.5 8.9 0.0 3.1 2 1 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC39074.1 - 0.015 14.6 0.1 7.4 5.9 0.0 2.6 2 0 0 2 2 2 0 AAA domain DUF87 PF01935.12 EGC39074.1 - 0.019 14.7 0.2 0.019 14.7 0.1 3.2 4 0 0 4 4 3 0 Domain of unknown function DUF87 MobB PF03205.9 EGC39074.1 - 0.02 14.6 0.6 4.3 7.0 0.1 2.6 2 0 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B DUF815 PF05673.8 EGC39074.1 - 0.023 13.6 0.1 4.2 6.2 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_18 PF13238.1 EGC39074.1 - 0.027 14.7 2.1 3.3 8.0 0.0 3.5 3 0 0 3 3 2 0 AAA domain cobW PF02492.14 EGC39074.1 - 0.031 13.7 1.1 0.12 11.8 0.1 2.2 2 0 0 2 2 2 0 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGC39074.1 - 0.063 13.1 0.0 2.4 8.0 0.0 2.7 2 0 0 2 2 2 0 AAA domain ATP_bind_1 PF03029.12 EGC39074.1 - 0.064 12.7 0.2 11 5.5 0.0 2.6 2 0 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_30 PF13604.1 EGC39074.1 - 0.11 12.0 0.3 24 4.4 0.0 2.9 3 0 0 3 3 3 0 AAA domain AAA_23 PF13476.1 EGC39074.1 - 0.58 10.4 17.7 0.043 14.1 0.8 4.4 5 1 0 5 5 3 0 AAA domain Piwi PF02171.12 EGC39075.1 - 1.9e-57 194.5 8.4 1.9e-57 194.5 5.8 2.4 2 1 0 2 2 2 1 Piwi domain PCI PF01399.22 EGC39076.1 - 4.7e-25 87.9 9.0 8.1e-25 87.1 1.5 3.2 3 0 0 3 3 3 1 PCI domain PCI_Csn8 PF10075.4 EGC39076.1 - 7.5e-15 54.9 0.9 1.6e-14 53.9 0.6 1.5 1 0 0 1 1 1 1 COP9 signalosome, subunit CSN8 TPR_12 PF13424.1 EGC39076.1 - 0.00059 19.7 1.7 0.67 9.9 0.0 4.0 3 2 0 4 4 4 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC39076.1 - 0.015 15.0 0.6 50 4.0 0.0 4.8 5 0 0 5 5 5 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39076.1 - 3.3 7.8 5.1 65 3.8 0.0 4.3 5 1 0 5 5 5 0 Tetratricopeptide repeat FNIP PF05725.7 EGC39078.1 - 6.9e-102 333.2 88.0 9.5e-14 51.0 0.9 13.4 11 3 3 14 14 14 13 FNIP Repeat DUF1769 PF08588.5 EGC39078.1 - 0.0062 16.4 22.0 29 4.7 0.0 10.4 7 2 6 13 13 13 2 Protein of unknown function (DUF1769) ORMDL PF04061.9 EGC39079.1 - 5.6e-42 142.5 5.5 6.3e-42 142.3 3.8 1.0 1 0 0 1 1 1 1 ORMDL family DUF4231 PF14015.1 EGC39079.1 - 0.0086 16.0 0.8 1.3 9.0 0.3 2.3 2 0 0 2 2 2 2 Protein of unknown function (DUF4231) DUF3360 PF11840.3 EGC39079.1 - 0.021 13.1 2.3 0.027 12.8 1.6 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3360) DUF3784 PF12650.2 EGC39079.1 - 0.075 12.9 2.7 2.1 8.3 0.1 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF3784) LAP1C PF05609.7 EGC39079.1 - 0.12 10.9 0.2 0.15 10.7 0.2 1.1 1 0 0 1 1 1 0 Lamina-associated polypeptide 1C (LAP1C) DUF3753 PF12575.3 EGC39079.1 - 1.6 8.5 5.5 0.91 9.3 0.2 2.7 2 1 1 3 3 3 0 Protein of unknown function (DUF3753) DUF846 PF05832.7 EGC39079.1 - 5.3 6.7 11.0 0.52 10.0 3.0 2.0 2 0 0 2 2 2 0 Eukaryotic protein of unknown function (DUF846) ERO1 PF04137.10 EGC39080.1 - 1.5e-113 379.4 3.8 1.5e-113 379.4 2.6 1.8 2 0 0 2 2 2 1 Endoplasmic Reticulum Oxidoreductin 1 (ERO1) DUF106 PF01956.11 EGC39080.1 - 0.051 13.0 1.4 0.096 12.2 0.1 2.0 2 0 0 2 2 2 0 Integral membrane protein DUF106 DUF4363 PF14276.1 EGC39080.1 - 0.095 12.4 6.5 0.11 12.1 1.2 2.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4363) EphA2_TM PF14575.1 EGC39080.1 - 0.15 12.4 0.4 1.2 9.5 0.0 2.4 2 0 0 2 2 2 0 Ephrin type-A receptor 2 transmembrane domain SID-1_RNA_chan PF13965.1 EGC39080.1 - 3.2 5.7 13.9 0.1 10.7 2.8 2.8 3 0 0 3 3 3 0 dsRNA-gated channel SID-1 FH2 PF02181.18 EGC39081.1 - 2.5e-84 283.3 19.6 2.5e-84 283.3 13.6 3.1 2 1 1 3 3 3 1 Formin Homology 2 Domain Drf_FH3 PF06367.11 EGC39081.1 - 1.5e-37 128.9 2.8 1.5e-37 128.9 1.9 2.5 2 0 0 2 2 2 1 Diaphanous FH3 Domain Drf_GBD PF06371.8 EGC39081.1 - 1.3e-18 67.0 0.1 1.3e-18 67.0 0.1 2.4 2 0 0 2 2 2 1 Diaphanous GTPase-binding Domain DER1 PF04511.10 EGC39082.1 - 9.8e-46 155.7 14.6 1.1e-45 155.5 10.1 1.0 1 0 0 1 1 1 1 Der1-like family Ribosomal_L21p PF00829.16 EGC39083.1 - 2.1e-29 101.5 2.4 2.7e-29 101.1 1.7 1.2 1 0 0 1 1 1 1 Ribosomal prokaryotic L21 protein Patatin PF01734.17 EGC39084.1 - 5.3e-28 98.3 0.0 9e-28 97.6 0.0 1.4 1 0 0 1 1 1 1 Patatin-like phospholipase DUF3928 PF13065.1 EGC39084.1 - 0.016 15.4 0.0 0.053 13.8 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF3928) Pal1 PF08316.6 EGC39084.1 - 0.19 12.1 1.3 0.67 10.3 0.9 1.9 1 0 0 1 1 1 0 Pal1 cell morphology protein Histone PF00125.19 EGC39086.1 - 2e-12 47.0 0.2 2.5e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC39086.1 - 8.1e-05 22.7 0.0 0.00023 21.2 0.0 1.7 2 0 0 2 2 2 1 Kinetochore component CENP-S TAF PF02969.12 EGC39086.1 - 0.00052 19.9 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ribosomal_L29e PF01779.12 EGC39086.1 - 0.0019 18.0 2.2 0.054 13.3 2.5 2.0 1 1 1 2 2 2 1 Ribosomal L29e protein family CBFD_NFYB_HMF PF00808.18 EGC39086.1 - 0.004 17.1 0.0 0.0093 16.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC39086.1 - 0.0041 16.8 0.1 0.0063 16.2 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EGC39086.1 - 0.028 14.2 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 EGC39086.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EGC39086.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T TPT PF03151.11 EGC39087.1 - 3.6e-05 23.4 3.5 4.5e-05 23.1 2.4 1.1 1 0 0 1 1 1 1 Triose-phosphate Transporter family zf-CCCH PF00642.19 EGC39088.1 - 5.8e-21 73.7 13.9 1.9e-12 46.5 1.7 2.3 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) zf-CCCH_2 PF14608.1 EGC39088.1 - 0.0043 16.9 7.1 0.48 10.5 0.3 2.6 2 0 0 2 2 2 2 Zinc finger C-x8-C-x5-C-x3-H type AAA_23 PF13476.1 EGC39088.1 - 0.97 9.7 22.7 3 8.1 11.7 2.2 2 0 0 2 2 2 0 AAA domain zf-DHHC PF01529.15 EGC39088.1 - 3.4 7.0 6.4 2.4 7.5 1.1 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase RCC1 PF00415.13 EGC39089.1 - 6e-69 228.0 15.6 9.6e-11 41.7 0.1 8.3 8 0 0 8 8 8 8 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC39089.1 - 3e-33 112.6 32.9 5.2e-07 29.1 0.2 8.3 9 0 0 9 9 9 7 Regulator of chromosome condensation (RCC1) repeat FtsJ PF01728.14 EGC39090.1 - 3.3e-06 27.2 0.0 5.9e-06 26.3 0.0 1.4 1 0 0 1 1 1 1 FtsJ-like methyltransferase Inhibitor_I29 PF08246.7 EGC39091.1 - 3e-16 59.4 0.1 8.1e-16 58.0 0.1 1.7 1 1 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) Bacteriocin_IIc PF10439.4 EGC39091.1 - 0.012 15.6 6.3 0.02 14.9 4.4 1.3 1 0 0 1 1 1 0 Bacteriocin class II with double-glycine leader peptide EspB PF05802.6 EGC39091.1 - 0.13 11.1 2.2 0.18 10.7 1.5 1.1 1 0 0 1 1 1 0 Enterobacterial EspB protein Glyco_trans_1_4 PF13692.1 EGC39092.1 - 5.6e-18 65.3 0.0 2.6e-17 63.2 0.0 1.9 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glycos_transf_1 PF00534.15 EGC39092.1 - 6e-14 51.8 0.0 1.1e-12 47.7 0.0 2.2 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_trans_4_4 PF13579.1 EGC39092.1 - 0.0024 18.0 0.0 0.0034 17.5 0.0 1.2 1 0 0 1 1 1 1 Glycosyl transferase 4-like domain Glyco_trans_1_2 PF13524.1 EGC39092.1 - 0.17 12.1 0.0 0.39 11.0 0.0 1.5 1 0 0 1 1 1 0 Glycosyl transferases group 1 DUF228 PF02989.9 EGC39092.1 - 0.94 9.0 5.8 1.4 8.4 1.4 2.2 1 1 1 2 2 2 0 Lyme disease proteins of unknown function Surp PF01805.15 EGC39094.1 - 0.11 12.1 2.5 0.33 10.6 0.1 2.2 2 0 0 2 2 2 0 Surp module Acyl_transf_1 PF00698.16 EGC39095.1 - 5.9e-41 140.8 0.0 7e-41 140.5 0.0 1.0 1 0 0 1 1 1 1 Acyl transferase domain DnaJ PF00226.26 EGC39096.1 - 3.1e-22 78.0 2.9 6.9e-22 76.9 2.0 1.6 1 0 0 1 1 1 1 DnaJ domain CTDII PF01556.13 EGC39096.1 - 8.6e-13 47.9 0.0 4.1e-11 42.6 0.0 3.0 3 0 0 3 3 3 1 DnaJ C terminal domain DnaJ_CXXCXGXG PF00684.14 EGC39096.1 - 0.091 12.8 16.5 1.1 9.3 11.4 2.4 1 1 0 1 1 1 0 DnaJ central domain zf-RING_2 PF13639.1 EGC39097.1 - 2.1e-11 43.4 9.3 3.4e-11 42.7 6.5 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39097.1 - 1.6e-08 34.1 7.1 2.4e-08 33.5 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39097.1 - 2e-07 31.0 7.5 4.4e-07 29.9 5.2 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC39097.1 - 2.4e-07 30.2 12.0 4.6e-07 29.3 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39097.1 - 9.8e-07 28.6 10.4 1.6e-06 28.0 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39097.1 - 2.7e-05 23.7 9.4 4.8e-05 23.0 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39097.1 - 0.0016 18.0 10.8 0.0028 17.2 7.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain DUF1510 PF07423.6 EGC39097.1 - 0.0038 16.6 2.9 0.0038 16.6 2.0 3.3 2 1 0 2 2 1 1 Protein of unknown function (DUF1510) zf-C3HC4_4 PF15227.1 EGC39097.1 - 0.007 16.2 9.4 0.015 15.1 5.9 2.1 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING IBR PF01485.16 EGC39097.1 - 0.019 14.7 10.5 0.052 13.4 7.3 1.8 1 0 0 1 1 1 0 IBR domain zf-RING_UBOX PF13445.1 EGC39097.1 - 0.042 13.5 4.2 0.17 11.6 2.9 2.1 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC39097.1 - 0.057 13.2 4.1 0.12 12.2 2.9 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC39097.1 - 0.073 12.9 7.4 0.14 12.0 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EGC39097.1 - 0.094 12.2 4.1 0.24 10.9 2.9 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EGC39097.1 - 0.25 10.9 8.2 0.49 9.9 5.7 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger Tetraspannin PF00335.15 EGC39097.1 - 6.5 5.9 11.7 0.028 13.7 1.1 2.2 2 0 0 2 2 2 0 Tetraspanin family zf-RING_2 PF13639.1 EGC39098.1 - 2.4e-11 43.2 9.3 4e-11 42.5 6.5 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39098.1 - 1.8e-08 33.8 7.1 2.8e-08 33.3 5.0 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39098.1 - 2.1e-07 30.9 7.6 5e-07 29.7 5.3 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC39098.1 - 2.9e-07 30.0 12.0 5.3e-07 29.1 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39098.1 - 1.1e-06 28.4 10.4 1.8e-06 27.8 7.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39098.1 - 3.2e-05 23.5 9.4 5.5e-05 22.8 6.5 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39098.1 - 0.0018 17.8 10.8 0.0032 17.0 7.5 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGC39098.1 - 0.0077 16.0 9.0 0.014 15.2 5.7 1.9 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING Hepar_II_III PF07940.8 EGC39098.1 - 0.016 15.0 2.5 0.18 11.6 0.0 3.4 1 1 1 3 3 3 0 Heparinase II/III-like protein IBR PF01485.16 EGC39098.1 - 0.02 14.7 10.3 0.051 13.4 7.1 1.7 1 0 0 1 1 1 0 IBR domain Prok-RING_4 PF14447.1 EGC39098.1 - 0.031 13.8 4.5 0.073 12.6 3.1 1.6 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_UBOX PF13445.1 EGC39098.1 - 0.045 13.4 4.2 0.19 11.4 2.9 2.2 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC39098.1 - 0.05 13.4 4.1 0.11 12.3 2.8 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC39098.1 - 0.078 12.8 7.2 0.16 11.8 5.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-MIZ PF02891.15 EGC39098.1 - 0.29 10.6 8.2 0.56 9.7 5.7 1.4 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-HC5HC2H PF13771.1 EGC39098.1 - 2.7 8.2 11.5 2.2 8.4 6.2 2.2 1 1 0 1 1 1 0 PHD-like zinc-binding domain LRR_6 PF13516.1 EGC39099.1 - 9e-09 34.5 16.7 0.072 13.1 0.7 7.4 6 1 1 7 7 7 3 Leucine Rich repeat LRR_7 PF13504.1 EGC39099.1 - 0.00091 19.0 7.8 1.8 9.0 0.0 6.2 4 1 0 4 4 4 1 Leucine rich repeat LRR_8 PF13855.1 EGC39099.1 - 0.0022 17.7 22.0 0.0028 17.3 3.5 4.3 3 2 2 5 5 5 2 Leucine rich repeat F-box-like PF12937.2 EGC39099.1 - 0.0022 17.6 0.2 0.0048 16.5 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_4 PF12799.2 EGC39099.1 - 0.0023 17.5 24.7 0.0078 15.8 2.9 4.6 4 2 1 5 5 5 3 Leucine Rich repeats (2 copies) F-box PF00646.28 EGC39099.1 - 0.0047 16.5 0.7 0.014 15.0 0.5 1.8 1 0 0 1 1 1 1 F-box domain LRR_1 PF00560.28 EGC39099.1 - 0.32 11.1 0.1 0.32 11.1 0.1 6.5 7 2 1 8 8 8 0 Leucine Rich Repeat Branch PF02485.16 EGC39100.1 - 9.1e-17 61.0 4.9 2.8e-16 59.4 3.4 1.7 1 1 0 1 1 1 1 Core-2/I-Branching enzyme GLE1 PF07817.8 EGC39101.1 - 4e-28 98.0 1.4 4e-28 98.0 0.9 3.6 3 1 1 4 4 4 1 GLE1-like protein Mlo PF03094.10 EGC39101.1 - 0.02 13.0 0.1 0.02 13.0 0.1 3.1 2 1 1 3 3 3 0 Mlo family Med15 PF09606.5 EGC39101.1 - 2 6.5 44.4 2.8 6.0 30.8 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal adh_short PF00106.20 EGC39103.1 - 3.3e-22 79.1 0.0 4.5e-22 78.7 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC39103.1 - 3.6e-12 46.5 0.0 4.7e-12 46.2 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC39103.1 - 2.1e-06 27.5 0.0 3.2e-06 26.9 0.0 1.3 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC39103.1 - 0.0013 17.9 0.0 0.0016 17.6 0.0 1.3 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC39103.1 - 0.0023 17.9 0.0 0.0039 17.2 0.0 1.5 1 0 0 1 1 1 1 NADH(P)-binding Polysacc_synt_2 PF02719.10 EGC39103.1 - 0.025 13.5 0.0 0.031 13.1 0.0 1.2 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGC39103.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.8 1 1 0 1 1 1 0 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGC39103.1 - 0.095 11.9 0.0 0.32 10.1 0.0 1.8 2 0 0 2 2 2 0 NmrA-like family DUF4334 PF14232.1 EGC39104.1 - 0.084 12.5 0.0 0.17 11.5 0.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF4334) AAA_16 PF13191.1 EGC39105.1 - 0.022 14.7 0.0 2.1 8.2 0.0 3.3 3 0 0 3 3 3 0 AAA ATPase domain AAA_19 PF13245.1 EGC39105.1 - 0.55 10.0 0.0 8.5 6.2 0.0 2.3 2 0 0 2 2 2 0 Part of AAA domain zf-RING_2 PF13639.1 EGC39106.1 - 2.9e-05 23.7 9.6 2.9e-05 23.7 6.6 2.2 2 0 0 2 2 2 1 Ring finger domain zf-C3HC4 PF00097.20 EGC39106.1 - 0.00028 20.4 13.1 0.0013 18.3 9.1 2.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC39106.1 - 0.00051 19.6 13.3 0.00051 19.6 9.2 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39106.1 - 0.0006 19.7 12.0 0.0006 19.7 8.3 2.3 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39106.1 - 0.0059 16.3 13.6 0.0059 16.3 9.4 2.4 2 0 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC39106.1 - 0.0065 16.3 6.1 0.0065 16.3 4.2 2.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC39106.1 - 0.03 14.1 4.7 0.057 13.2 3.3 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein MOR2-PAG1_N PF14222.1 EGC39106.1 - 0.55 8.8 11.1 1.2 7.7 7.7 1.6 1 0 0 1 1 1 0 Cell morphogenesis N-terminal zf-rbx1 PF12678.2 EGC39106.1 - 0.77 9.9 15.3 0.034 14.2 5.2 2.4 2 0 0 2 2 2 0 RING-H2 zinc finger Romo1 PF10247.4 EGC39107.1 - 2.2e-15 56.6 10.0 2.4e-15 56.4 7.0 1.0 1 0 0 1 1 1 1 Reactive mitochondrial oxygen species modulator 1 Na_Pi_cotrans PF02690.10 EGC39107.1 - 0.041 13.5 0.4 0.046 13.4 0.3 1.1 1 0 0 1 1 1 0 Na+/Pi-cotransporter Tim17 PF02466.14 EGC39107.1 - 0.3 11.1 3.5 0.33 10.9 2.4 1.1 1 0 0 1 1 1 0 Tim17/Tim22/Tim23/Pmp24 family ABC_membrane PF00664.18 EGC39108.1 - 3.8e-42 144.6 26.0 7.3e-42 143.6 18.0 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region Peptidase_S8 PF00082.17 EGC39108.1 - 3.5e-36 124.7 5.9 7.9e-36 123.6 4.1 1.6 1 0 0 1 1 1 1 Subtilase family ABC_tran PF00005.22 EGC39108.1 - 2e-32 112.3 0.0 7.3e-32 110.5 0.0 2.0 1 0 0 1 1 1 1 ABC transporter SMC_N PF02463.14 EGC39108.1 - 2.4e-10 40.0 0.0 1.8e-09 37.1 0.0 2.7 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC39108.1 - 1.5e-06 28.4 0.2 1.5e-06 28.4 0.1 5.5 4 1 0 4 4 4 2 AAA domain AAA_17 PF13207.1 EGC39108.1 - 0.0013 19.5 0.0 0.006 17.3 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_29 PF13555.1 EGC39108.1 - 0.0035 16.8 0.0 0.0097 15.4 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_22 PF13401.1 EGC39108.1 - 0.0043 17.2 0.1 0.016 15.3 0.1 1.9 1 1 0 1 1 1 1 AAA domain AAA_16 PF13191.1 EGC39108.1 - 0.011 15.6 0.0 0.026 14.5 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain DUF258 PF03193.11 EGC39108.1 - 0.017 14.3 0.0 0.06 12.5 0.0 1.9 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_33 PF13671.1 EGC39108.1 - 0.2 11.5 0.0 0.69 9.7 0.0 2.0 2 0 0 2 2 2 0 AAA domain ABC_membrane PF00664.18 EGC39109.1 - 5e-42 144.2 26.9 5e-42 144.2 18.6 1.7 2 0 0 2 2 2 1 ABC transporter transmembrane region Peptidase_S8 PF00082.17 EGC39109.1 - 2.9e-39 134.9 2.0 2.9e-39 134.9 1.4 2.3 2 0 0 2 2 2 1 Subtilase family ABC_tran PF00005.22 EGC39109.1 - 4.3e-31 108.0 0.0 4.3e-31 108.0 0.0 2.2 2 0 0 2 2 2 1 ABC transporter SMC_N PF02463.14 EGC39109.1 - 9.1e-07 28.3 3.5 9.1e-07 28.3 2.4 2.8 2 1 0 2 2 2 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC39109.1 - 7.9e-05 22.7 33.0 0.029 14.3 0.0 4.9 4 1 1 5 5 5 2 AAA domain AAA_17 PF13207.1 EGC39109.1 - 0.0002 22.1 0.9 0.00053 20.8 0.0 2.2 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC39109.1 - 0.005 16.9 0.0 0.018 15.1 0.0 1.9 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC39109.1 - 0.32 11.3 0.0 0.32 11.3 0.0 3.5 3 1 0 3 3 3 0 AAA domain AAA_16 PF13191.1 EGC39109.1 - 0.39 10.6 0.1 1.4 8.8 0.1 1.9 1 1 0 1 1 1 0 AAA ATPase domain LRR_6 PF13516.1 EGC39110.1 - 7.2e-17 59.5 2.1 0.0014 18.4 0.1 5.2 5 0 0 5 5 5 4 Leucine Rich repeat F-box-like PF12937.2 EGC39110.1 - 2.3e-06 27.2 0.1 4e-06 26.4 0.0 1.4 1 0 0 1 1 1 1 F-box-like LRR_1 PF00560.28 EGC39110.1 - 0.00021 20.8 1.9 24 5.4 0.0 5.7 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 EGC39110.1 - 0.0016 18.0 7.7 0.057 13.0 0.4 4.0 3 1 0 4 4 4 2 Leucine Rich repeats (2 copies) UPF0302 PF08864.5 EGC39110.1 - 0.0047 16.7 0.1 0.03 14.1 0.0 2.1 1 1 1 2 2 2 1 UPF0302 domain LRR_8 PF13855.1 EGC39110.1 - 0.0066 16.1 8.2 0.56 9.9 0.7 4.1 2 1 2 4 4 4 1 Leucine rich repeat DASH_Dad4 PF08650.5 EGC39110.1 - 0.015 15.1 0.9 0.015 15.1 0.6 2.7 3 0 0 3 3 3 0 DASH complex subunit Dad4 F-box PF00646.28 EGC39110.1 - 0.051 13.2 0.1 0.3 10.7 0.0 2.1 2 0 0 2 2 2 0 F-box domain Peptidase_C1 PF00112.18 EGC39112.1 - 2.6e-54 184.3 6.2 2.6e-54 184.3 4.3 2.0 2 1 0 2 2 2 1 Papain family cysteine protease CAP PF00188.21 EGC39112.1 - 3.1e-08 34.1 7.6 3.1e-08 34.1 5.2 2.1 2 1 0 2 2 2 1 Cysteine-rich secretory protein family EF1_GNE PF00736.14 EGC39113.1 - 5e-20 70.9 2.6 5.8e-20 70.7 1.8 1.0 1 0 0 1 1 1 1 EF-1 guanine nucleotide exchange domain Med9 PF07544.8 EGC39113.1 - 0.015 14.9 0.1 0.84 9.4 0.0 2.1 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Transposase_22 PF02994.9 EGC39113.1 - 0.11 10.9 2.0 0.12 10.8 1.4 1.0 1 0 0 1 1 1 0 L1 transposable element TBPIP PF07106.8 EGC39113.1 - 0.17 11.4 1.5 0.29 10.6 1.0 1.3 1 1 0 1 1 1 0 Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ETC_C1_NDUFA5 PF04716.9 EGC39113.1 - 0.18 11.3 0.8 1.7 8.1 0.1 2.1 2 0 0 2 2 2 0 ETC complex I subunit conserved region V-SNARE PF05008.10 EGC39113.1 - 0.33 11.1 1.6 1 9.5 0.4 1.9 2 0 0 2 2 2 0 Vesicle transport v-SNARE protein N-terminus MMS1_N PF10433.4 EGC39114.1 - 3e-84 282.9 0.4 4.6e-84 282.3 0.3 1.2 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term CPSF_A PF03178.10 EGC39114.1 - 2.8e-64 217.2 0.0 2.8e-63 213.9 0.0 2.4 2 0 0 2 2 2 1 CPSF A subunit region TruB_C PF09142.6 EGC39114.1 - 0.014 14.9 0.0 0.034 13.7 0.0 1.6 1 0 0 1 1 1 0 tRNA Pseudouridine synthase II, C terminal Pkinase PF00069.20 EGC39115.1 - 1.2e-64 217.9 0.0 1.2e-64 217.9 0.0 2.2 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39115.1 - 8.8e-43 146.2 0.0 1.6e-42 145.3 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase GCC2_GCC3 PF07699.8 EGC39115.1 - 3.9e-12 45.5 63.9 5.7e-05 22.6 1.9 7.3 1 1 7 8 8 8 8 GCC2 and GCC3 Kinase-like PF14531.1 EGC39115.1 - 0.00015 20.8 0.0 0.0005 19.1 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC39115.1 - 0.00042 20.1 0.0 0.0015 18.3 0.0 1.7 1 1 1 2 2 2 1 Phosphotransferase enzyme family Kdo PF06293.9 EGC39115.1 - 0.013 14.5 0.0 0.023 13.7 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family NCD3G PF07562.9 EGC39115.1 - 0.22 11.2 49.8 0.34 10.6 1.5 6.6 3 2 0 5 5 5 0 Nine Cysteines Domain of family 3 GPCR DPBB_1 PF03330.13 EGC39116.1 - 1.1e-12 47.7 0.2 3.7e-12 46.0 0.1 2.0 2 0 0 2 2 2 1 Rare lipoprotein A (RlpA)-like double-psi beta-barrel Pollen_allerg_1 PF01357.16 EGC39116.1 - 1.8e-06 27.6 0.1 5e-06 26.2 0.1 1.7 1 0 0 1 1 1 1 Pollen allergen Barwin PF00967.12 EGC39116.1 - 7.1e-05 22.4 0.7 0.00013 21.6 0.5 1.4 1 0 0 1 1 1 1 Barwin family Cerato-platanin PF07249.7 EGC39116.1 - 0.0011 19.0 1.0 0.0011 19.0 0.7 1.8 2 1 0 2 2 2 1 Cerato-platanin Sel1 PF08238.7 EGC39117.1 - 1.3e-31 108.2 8.2 5.8e-07 29.9 0.2 6.1 6 0 0 6 6 6 6 Sel1 repeat TPR_11 PF13414.1 EGC39117.1 - 7.6e-06 25.4 3.0 0.00012 21.5 0.4 3.0 2 2 1 3 3 3 1 TPR repeat TPR_12 PF13424.1 EGC39117.1 - 0.002 18.0 0.5 0.023 14.6 0.1 2.9 2 1 0 2 2 2 1 Tetratricopeptide repeat TPR_17 PF13431.1 EGC39117.1 - 0.017 15.2 1.7 18 5.8 0.0 3.9 2 1 1 3 3 3 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39117.1 - 0.36 10.8 11.3 41 4.4 0.0 5.6 5 2 0 5 5 5 0 Tetratricopeptide repeat TPR_1 PF00515.23 EGC39117.1 - 1.5 8.5 14.9 8.4 6.1 0.1 5.8 7 0 0 7 7 7 0 Tetratricopeptide repeat EGF_2 PF07974.8 EGC39118.1 - 0.049 13.7 10.3 0.12 12.6 7.2 1.6 1 0 0 1 1 1 0 EGF-like domain NUDIX PF00293.23 EGC39119.1 - 3.2e-07 30.0 0.0 5.1e-07 29.4 0.0 1.4 1 0 0 1 1 1 1 NUDIX domain Ank_2 PF12796.2 EGC39120.1 - 0.00049 20.3 0.2 0.019 15.2 0.1 3.4 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) F5_F8_type_C PF00754.20 EGC39121.1 - 9e-26 90.2 1.0 1.6e-25 89.3 0.7 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC39121.1 - 1.7e-20 72.4 0.2 4.4e-20 71.1 0.2 1.8 1 0 0 1 1 1 1 H-type lectin domain F5_F8_type_C PF00754.20 EGC39122.1 - 1.3e-22 80.0 0.4 2.4e-22 79.1 0.3 1.5 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC39122.1 - 2.3e-19 68.8 0.4 5.2e-19 67.6 0.3 1.7 1 0 0 1 1 1 1 H-type lectin domain ubiquitin PF00240.18 EGC39123.1 - 0.00018 20.8 0.0 0.00038 19.7 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin family Ubiquitin_2 PF14560.1 EGC39123.1 - 0.012 15.8 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 Ubiquitin-like domain NPIP PF06409.6 EGC39123.1 - 0.019 13.7 0.0 0.032 12.9 0.0 1.3 1 0 0 1 1 1 0 Nuclear pore complex interacting protein (NPIP) TUG-UBL1 PF11470.3 EGC39123.1 - 0.054 13.4 0.1 3 7.8 0.0 2.3 1 1 1 2 2 2 0 GLUT4 regulating protein TUG zf-RING_2 PF13639.1 EGC39124.1 - 2.2e-11 43.3 9.3 4e-11 42.5 6.5 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39124.1 - 1.5e-08 34.1 7.1 2.8e-08 33.2 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39124.1 - 2.2e-07 30.9 7.8 7.2e-07 29.2 5.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC39124.1 - 5.4e-07 29.1 12.0 5.4e-07 29.1 8.3 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39124.1 - 1.1e-06 28.5 10.4 1.9e-06 27.8 7.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39124.1 - 2.7e-05 23.8 9.4 5.6e-05 22.7 6.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39124.1 - 0.0017 17.8 10.8 0.0033 16.9 7.5 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-C3HC4_4 PF15227.1 EGC39124.1 - 0.008 16.0 9.5 0.019 14.8 6.0 2.2 1 1 1 2 2 2 1 zinc finger of C3HC4-type, RING IBR PF01485.16 EGC39124.1 - 0.017 14.9 10.5 0.061 13.1 7.2 2.0 1 0 0 1 1 1 0 IBR domain zf-Apc11 PF12861.2 EGC39124.1 - 0.051 13.4 4.1 0.14 11.9 2.9 1.8 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DUF1272 PF06906.6 EGC39124.1 - 0.074 12.9 7.4 0.16 11.8 5.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Prok-RING_4 PF14447.1 EGC39124.1 - 0.083 12.4 4.1 0.29 10.7 2.9 2.0 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-MIZ PF02891.15 EGC39124.1 - 0.19 11.2 8.2 0.57 9.7 5.7 1.8 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGC39124.1 - 1.9 8.2 10.1 0.2 11.4 2.9 2.7 2 0 0 2 2 1 0 RING-type zinc-finger HTH_9 PF08221.6 EGC39126.1 - 3.2e-17 62.1 0.5 4e-10 39.3 0.1 3.4 3 0 0 3 3 3 3 RNA polymerase III subunit RPC82 helix-turn-helix domain RNA_pol_Rpc82 PF05645.8 EGC39126.1 - 0.00011 21.8 7.6 0.0033 17.0 3.0 2.8 2 1 0 2 2 2 2 RNA polymerase III subunit RPC82 EF-hand_9 PF14658.1 EGC39126.1 - 0.00042 20.1 0.1 0.0061 16.4 0.0 2.5 2 0 0 2 2 2 1 EF-hand domain TFIIE_alpha PF02002.12 EGC39126.1 - 0.00071 19.0 3.6 0.014 14.8 0.0 3.8 4 1 1 5 5 5 1 TFIIE alpha subunit Iso_dh PF00180.15 EGC39127.1 - 2.2e-73 247.2 0.0 2.5e-73 247.0 0.0 1.0 1 0 0 1 1 1 1 Isocitrate/isopropylmalate dehydrogenase BCLP PF12304.3 EGC39127.1 - 0.17 11.2 0.0 0.28 10.5 0.0 1.3 1 0 0 1 1 1 0 Beta-casein like protein Ras PF00071.17 EGC39128.1 - 4e-58 195.3 0.5 5.5e-58 194.9 0.3 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39128.1 - 1e-21 77.6 0.1 1.7e-21 76.8 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39128.1 - 5.9e-14 51.6 0.3 7e-14 51.4 0.2 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC39128.1 - 4e-07 29.6 0.1 2.3e-06 27.1 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC39128.1 - 5.4e-06 25.7 0.3 6.1e-06 25.5 0.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region SRPRB PF09439.5 EGC39128.1 - 1.9e-05 23.9 0.1 3.4e-05 23.1 0.0 1.4 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC39128.1 - 0.00015 21.6 0.1 0.00036 20.4 0.1 1.6 1 1 0 2 2 2 1 50S ribosome-binding GTPase FeoB_N PF02421.13 EGC39128.1 - 0.0065 15.7 0.1 0.096 11.9 0.1 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B Acetyltransf_8 PF13523.1 EGC39128.1 - 0.054 13.3 0.0 0.076 12.8 0.0 1.1 1 0 0 1 1 1 0 Acetyltransferase (GNAT) domain Ribonuc_L-PSP PF01042.16 EGC39129.1 - 1.1e-40 138.0 0.1 1.3e-40 137.9 0.1 1.0 1 0 0 1 1 1 1 Endoribonuclease L-PSP VRR_NUC PF08774.6 EGC39130.1 - 1.7e-16 60.0 0.0 3.7e-16 58.9 0.0 1.6 1 0 0 1 1 1 1 VRR-NUC domain Corona_nucleoca PF00937.13 EGC39130.1 - 0.0032 16.4 10.4 0.0032 16.4 7.2 4.8 5 0 0 5 5 5 1 Coronavirus nucleocapsid protein ANTH PF07651.11 EGC39131.1 - 0.11 11.1 2.5 0.22 10.2 1.7 1.4 1 0 0 1 1 1 0 ANTH domain BUD22 PF09073.5 EGC39131.1 - 0.16 11.0 20.9 0.25 10.3 14.5 1.4 1 0 0 1 1 1 0 BUD22 Clathrin_lg_ch PF01086.12 EGC39131.1 - 1.3 8.9 26.1 0.29 11.0 0.5 3.6 2 1 1 3 3 3 0 Clathrin light chain TMEM237 PF15383.1 EGC39131.1 - 5.3 6.0 9.0 1.6 7.7 3.8 1.8 2 0 0 2 2 2 0 Transmembrane protein 237 ZZ PF00569.12 EGC39132.1 - 3.5e-10 39.2 4.2 6e-10 38.5 2.9 1.3 1 0 0 1 1 1 1 Zinc finger, ZZ type Myb_DNA-binding PF00249.26 EGC39132.1 - 5.1e-10 39.2 0.2 9.6e-10 38.3 0.1 1.5 1 0 0 1 1 1 1 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC39132.1 - 0.00027 20.9 0.1 0.0013 18.8 0.0 2.2 2 0 0 2 2 2 1 Myb-like DNA-binding domain Cript PF10235.4 EGC39132.1 - 7.8 6.9 10.6 0.6 10.4 1.6 2.4 2 1 0 2 2 2 0 Microtubule-associated protein CRIPT ABC2_membrane PF01061.19 EGC39133.1 - 1.6e-33 115.6 32.7 8.1e-29 100.2 12.6 2.5 2 0 0 2 2 2 2 ABC-2 type transporter ABC_tran PF00005.22 EGC39133.1 - 8.2e-23 81.2 0.0 4.5e-19 69.1 0.0 2.5 2 0 0 2 2 2 2 ABC transporter PDR_assoc PF08370.6 EGC39133.1 - 1.9e-05 24.0 4.1 2.2e-05 23.8 0.1 2.6 2 0 0 2 2 2 1 Plant PDR ABC transporter associated AAA_18 PF13238.1 EGC39133.1 - 0.00053 20.3 0.4 0.0026 18.0 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_25 PF13481.1 EGC39133.1 - 0.0026 17.1 0.0 0.024 14.0 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC39133.1 - 0.0034 18.2 4.9 0.0052 17.5 0.0 3.2 3 1 1 4 4 3 1 AAA domain AAA_5 PF07728.9 EGC39133.1 - 0.03 14.0 0.0 0.065 12.9 0.0 1.7 1 1 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC39133.1 - 0.038 14.1 0.0 0.12 12.5 0.0 1.8 1 0 0 1 1 1 0 AAA domain AAA_28 PF13521.1 EGC39133.1 - 0.044 13.7 0.0 0.075 12.9 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA PF00004.24 EGC39133.1 - 0.063 13.4 0.1 0.19 11.9 0.0 1.8 2 0 0 2 2 1 0 ATPase family associated with various cellular activities (AAA) DUF258 PF03193.11 EGC39133.1 - 0.083 12.0 0.0 0.16 11.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_16 PF13191.1 EGC39133.1 - 0.1 12.5 0.0 0.18 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGC39133.1 - 0.15 11.9 0.0 0.29 11.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain ArgK PF03308.11 EGC39133.1 - 0.19 10.4 0.0 0.33 9.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein UCR_14kD PF02271.11 EGC39134.1 - 1.9e-17 62.9 0.4 2.3e-17 62.6 0.3 1.1 1 0 0 1 1 1 1 Ubiquinol-cytochrome C reductase complex 14kD subunit Cyclin_N PF00134.18 EGC39135.1 - 2.1e-24 85.4 0.6 4.8e-24 84.3 0.4 1.6 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin_C PF02984.14 EGC39135.1 - 0.0013 18.6 0.1 0.0035 17.2 0.1 1.8 1 0 0 1 1 1 1 Cyclin, C-terminal domain GEMIN8 PF15348.1 EGC39135.1 - 0.016 15.2 0.1 0.025 14.6 0.1 1.2 1 0 0 1 1 1 0 Gemini of Cajal bodies-associated protein 8 DPM3 PF08285.6 EGC39136.1 - 1.4e-32 111.3 0.6 1.6e-32 111.2 0.4 1.0 1 0 0 1 1 1 1 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) RICTOR_N PF14664.1 EGC39137.1 - 5.2e-79 265.5 1.0 1.2e-78 264.3 0.7 1.7 1 0 0 1 1 1 1 Rapamycin-insensitive companion of mTOR, N-term RICTOR_M PF14666.1 EGC39137.1 - 8e-69 231.0 5.8 8e-69 231.0 4.0 2.4 3 0 0 3 3 3 1 Rapamycin-insensitive companion of mTOR, middle domain RasGEF_N_2 PF14663.1 EGC39137.1 - 6.9e-33 113.0 0.8 2.8e-32 111.0 0.2 2.4 2 0 0 2 2 2 1 Rapamycin-insensitive companion of mTOR RasGEF_N domain RICTOR_V PF14668.1 EGC39137.1 - 2.3e-23 81.9 0.2 5.2e-21 74.3 0.0 3.9 4 0 0 4 4 4 1 Rapamycin-insensitive companion of mTOR, domain 5 Glyoxalase PF00903.20 EGC39138.1 - 2.3e-22 79.3 3.1 9.7e-16 57.9 0.1 2.2 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_4 PF13669.1 EGC39138.1 - 2e-10 40.6 0.2 0.00045 20.1 0.1 2.5 2 0 0 2 2 2 2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily Glyoxalase_5 PF14696.1 EGC39138.1 - 6.9e-09 35.7 0.2 1.5e-08 34.6 0.1 1.5 1 0 0 1 1 1 1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal Glyoxalase_2 PF12681.2 EGC39138.1 - 1.4e-08 35.2 0.1 0.0032 18.0 0.0 2.7 3 0 0 3 3 3 2 Glyoxalase-like domain Glyoxalase_3 PF13468.1 EGC39138.1 - 0.0013 18.6 0.1 3.7 7.4 0.0 3.6 3 1 0 3 3 3 2 Glyoxalase-like domain adh_short_C2 PF13561.1 EGC39139.1 - 8e-18 65.0 0.0 1.3e-17 64.4 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGC39139.1 - 2.4e-17 63.3 0.0 3.2e-17 62.9 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC39139.1 - 1.9e-05 24.4 0.0 2.5e-05 24.0 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC39139.1 - 0.00019 20.6 0.0 0.00024 20.3 0.0 1.1 1 0 0 1 1 1 1 Fungal family of unknown function (DUF1776) Epimerase PF01370.16 EGC39139.1 - 0.00046 19.6 0.0 0.00096 18.6 0.0 1.5 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC39139.1 - 0.00049 18.8 0.2 0.00078 18.2 0.2 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_10 PF13460.1 EGC39139.1 - 0.031 14.2 0.0 0.065 13.2 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding DUF2404 PF10296.4 EGC39141.1 - 1.7e-09 37.6 1.9 8.2e-09 35.4 0.0 2.8 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Sad1_UNC PF07738.8 EGC39142.1 - 2.5e-32 111.4 2.7 4.5e-32 110.6 0.3 2.6 2 0 0 2 2 2 1 Sad1 / UNC-like C-terminal Kelch_6 PF13964.1 EGC39143.1 - 3.2e-11 42.8 1.0 0.00036 20.5 0.0 3.9 3 1 1 4 4 4 2 Kelch motif zf-B_box PF00643.19 EGC39143.1 - 3e-07 30.2 12.5 3e-07 30.2 8.6 3.3 3 0 0 3 3 3 1 B-box zinc finger Kelch_4 PF13418.1 EGC39143.1 - 4e-07 29.6 0.1 0.032 14.0 0.0 3.9 4 0 0 4 4 4 2 Galactose oxidase, central domain Kelch_1 PF01344.20 EGC39143.1 - 9.1e-07 28.3 0.5 0.072 12.6 0.0 3.3 2 0 0 2 2 2 2 Kelch motif Kelch_5 PF13854.1 EGC39143.1 - 0.019 14.9 0.1 3 7.8 0.0 2.9 2 0 0 2 2 2 0 Kelch motif Spc7_N PF15402.1 EGC39143.1 - 0.77 7.6 22.1 1.3 6.9 15.3 1.3 1 0 0 1 1 1 0 N-terminus of kinetochore NMS complex subunit Spc7 RFC1 PF08519.7 EGC39144.1 - 2.8e-43 147.3 1.8 1.2e-42 145.2 0.0 3.0 3 0 0 3 3 3 1 Replication factor RFC1 C terminal domain AAA PF00004.24 EGC39144.1 - 6e-12 45.8 0.1 2.7e-10 40.5 0.0 2.7 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) BRCT PF00533.21 EGC39144.1 - 3.1e-10 40.0 0.0 1.2e-09 38.2 0.0 2.1 1 0 0 1 1 1 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC39144.1 - 4.4e-06 26.4 0.0 1.1e-05 25.1 0.0 1.7 1 0 0 1 1 1 1 twin BRCT domain RuvB_N PF05496.7 EGC39144.1 - 4.4e-06 25.9 0.0 8.6e-06 24.9 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_17 PF13207.1 EGC39144.1 - 0.0014 19.4 0.2 0.0078 17.0 0.0 2.5 2 0 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC39144.1 - 0.012 15.7 0.0 0.037 14.1 0.0 1.9 1 0 0 1 1 1 0 AAA domain AAA_16 PF13191.1 EGC39144.1 - 0.038 13.9 0.0 0.088 12.7 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain AAA_33 PF13671.1 EGC39144.1 - 0.054 13.3 0.0 0.19 11.6 0.0 2.0 1 0 0 1 1 1 0 AAA domain Glyco_hydro_18 PF00704.23 EGC39145.1 - 9.7e-69 232.4 3.0 1.2e-68 232.0 2.1 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 18 TPR_17 PF13431.1 EGC39146.1 - 7.2e-56 181.7 58.6 7.8e-06 25.7 1.0 18.4 18 0 0 18 18 18 14 Tetratricopeptide repeat TPR_11 PF13414.1 EGC39146.1 - 8.9e-21 73.3 51.5 0.091 12.4 0.2 15.9 16 2 1 17 17 17 9 TPR repeat zf-B_box PF00643.19 EGC39146.1 - 4.9e-07 29.5 6.2 4.9e-07 29.5 4.3 3.7 4 0 0 4 4 4 1 B-box zinc finger zf-RING_5 PF14634.1 EGC39146.1 - 0.0008 19.0 8.3 0.0008 19.0 5.8 2.9 2 1 0 2 2 2 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC39146.1 - 0.0095 15.7 3.8 0.0095 15.7 2.6 3.2 4 0 0 4 4 4 1 zinc finger of C3HC4-type, RING FYVE PF01363.16 EGC39146.1 - 0.76 9.7 14.1 0.38 10.6 2.4 2.7 3 0 0 3 3 3 0 FYVE zinc finger zf-RING_6 PF14835.1 EGC39146.1 - 3.6 7.4 8.9 12 5.7 1.5 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein PIG-Y PF15159.1 EGC39147.1 - 1.3e-31 108.5 7.8 1.7e-31 108.2 5.4 1.1 1 0 0 1 1 1 1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Pex14_N PF04695.8 EGC39147.1 - 0.057 13.4 2.0 0.071 13.1 1.4 1.2 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region EF-hand_1 PF00036.27 EGC39148.1 - 1.8e-21 73.7 9.0 2.8e-06 26.2 0.5 4.3 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC39148.1 - 4.1e-20 71.6 4.4 1.7e-10 40.8 0.4 2.4 2 0 0 2 2 2 2 EF-hand domain pair EF-hand_6 PF13405.1 EGC39148.1 - 1.3e-18 65.0 1.8 1.5e-05 24.5 0.0 4.3 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC39148.1 - 1.1e-13 49.8 9.8 6.1e-05 22.1 0.2 4.4 4 0 0 4 4 4 3 EF hand EF-hand_8 PF13833.1 EGC39148.1 - 4.9e-11 42.0 9.8 1.7e-05 24.3 1.6 4.5 3 1 1 4 4 4 3 EF-hand domain pair EF-hand_4 PF12763.2 EGC39148.1 - 1.4e-05 24.7 2.6 0.12 12.1 0.0 3.0 1 1 0 2 2 2 2 Cytoskeletal-regulatory complex EF hand SPARC_Ca_bdg PF10591.4 EGC39148.1 - 0.00028 20.8 0.1 0.51 10.3 0.0 2.2 2 0 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_9 PF14658.1 EGC39148.1 - 0.0003 20.6 0.0 0.047 13.5 0.0 2.8 3 0 0 3 3 3 1 EF-hand domain DUF1880 PF08976.6 EGC39148.1 - 0.025 14.7 0.0 0.38 10.9 0.0 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF1880) DUF807 PF05660.6 EGC39148.1 - 0.032 13.9 0.5 0.047 13.3 0.1 1.5 2 0 0 2 2 2 0 Coxiella burnetii protein of unknown function (DUF807) DUF241 PF03087.9 EGC39148.1 - 0.043 13.3 1.1 0.058 12.8 0.8 1.2 1 0 0 1 1 1 0 Arabidopsis protein of unknown function DUF4020 PF13212.1 EGC39148.1 - 0.065 12.8 0.4 0.1 12.1 0.0 1.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4020) Dockerin_1 PF00404.13 EGC39148.1 - 1.1 9.1 12.1 1.6 8.5 1.1 3.0 3 0 0 3 3 3 0 Dockerin type I repeat Glyco_transf_10 PF00852.14 EGC39149.1 - 8.4e-38 129.8 9.6 1.4e-37 129.0 6.7 1.3 1 0 0 1 1 1 1 Glycosyltransferase family 10 (fucosyltransferase) Laminin_G_3 PF13385.1 EGC39149.1 - 9.8e-24 84.3 0.0 1.6e-23 83.6 0.0 1.3 1 0 0 1 1 1 1 Concanavalin A-like lectin/glucanases superfamily Sialidase PF02973.11 EGC39149.1 - 0.00022 20.2 0.2 0.00061 18.8 0.2 1.7 1 0 0 1 1 1 1 Sialidase, N-terminal domain DUF1681 PF07933.9 EGC39150.1 - 0.038 13.5 0.0 0.044 13.3 0.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1681) EF-hand_7 PF13499.1 EGC39152.1 - 4.8e-21 74.6 4.1 9.8e-10 38.4 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_1 PF00036.27 EGC39152.1 - 5.5e-20 69.0 10.3 5.2e-06 25.3 0.4 4.2 4 0 0 4 4 4 4 EF hand EF-hand_6 PF13405.1 EGC39152.1 - 4.3e-19 66.6 3.2 2.3e-05 23.8 0.0 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_8 PF13833.1 EGC39152.1 - 2.5e-10 39.8 4.7 0.0076 15.8 0.1 4.1 4 0 0 4 4 4 3 EF-hand domain pair EF-hand_5 PF13202.1 EGC39152.1 - 2.2e-09 36.2 4.3 0.0059 15.9 0.0 4.4 4 0 0 4 4 4 3 EF hand SPARC_Ca_bdg PF10591.4 EGC39152.1 - 2.5e-09 37.1 6.0 0.0068 16.4 0.3 3.1 2 1 1 3 3 3 3 Secreted protein acidic and rich in cysteine Ca binding region FF PF01846.14 EGC39152.1 - 0.005 16.7 0.1 0.3 11.0 0.0 2.6 2 0 0 2 2 2 1 FF domain DUF1636 PF07845.6 EGC39152.1 - 0.025 14.8 0.0 4.4 7.5 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF1636) EF-hand_1 PF00036.27 EGC39153.1 - 1.3e-23 80.4 12.7 1.7e-06 26.8 0.4 4.1 4 0 0 4 4 4 4 EF hand EF-hand_7 PF13499.1 EGC39153.1 - 8.3e-23 80.3 3.5 2.2e-10 40.4 0.1 3.1 3 0 0 3 3 3 3 EF-hand domain pair EF-hand_6 PF13405.1 EGC39153.1 - 8.2e-21 71.9 5.1 0.00011 21.8 0.1 4.2 4 0 0 4 4 4 4 EF-hand domain EF-hand_5 PF13202.1 EGC39153.1 - 4e-16 57.5 4.0 0.00069 18.8 0.0 4.4 4 0 0 4 4 4 4 EF hand EF-hand_8 PF13833.1 EGC39153.1 - 3.4e-14 52.1 5.3 8.5e-05 22.0 0.2 4.2 4 0 0 4 4 4 3 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC39153.1 - 4.5e-09 36.3 6.1 4.8e-05 23.3 2.2 2.5 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region DUF1636 PF07845.6 EGC39153.1 - 0.0012 19.0 0.0 0.58 10.4 0.0 2.8 3 1 0 3 3 3 1 Protein of unknown function (DUF1636) FF PF01846.14 EGC39153.1 - 0.0031 17.4 0.1 0.25 11.3 0.0 2.5 2 1 0 2 2 2 1 FF domain EF-hand_like PF09279.6 EGC39153.1 - 0.0056 16.6 0.9 0.83 9.7 0.0 3.1 2 2 1 3 3 3 1 Phosphoinositide-specific phospholipase C, efhand-like PgpA PF04608.8 EGC39153.1 - 0.027 14.2 0.1 1.6 8.4 0.0 2.7 3 0 0 3 3 3 0 Phosphatidylglycerophosphatase A DUF1654 PF07867.6 EGC39153.1 - 0.1 11.9 0.5 0.57 9.5 0.1 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1654) EF-hand_10 PF14788.1 EGC39153.1 - 0.34 10.6 4.5 2.9 7.6 0.1 3.4 3 1 1 4 4 4 0 EF hand CDC45 PF02724.9 EGC39154.1 - 1.7e-164 548.2 13.4 2.1e-164 548.0 9.3 1.1 1 0 0 1 1 1 1 CDC45-like protein YL1 PF05764.8 EGC39154.1 - 0.00025 20.7 29.6 0.00048 19.8 20.5 1.4 1 0 0 1 1 1 1 YL1 nuclear protein Nop14 PF04147.7 EGC39154.1 - 0.00046 18.2 24.4 0.00067 17.7 16.9 1.1 1 0 0 1 1 1 1 Nop14-like family SDA1 PF05285.7 EGC39154.1 - 0.02 14.2 25.2 0.033 13.4 17.5 1.3 1 0 0 1 1 1 0 SDA1 Daxx PF03344.10 EGC39154.1 - 0.049 12.1 20.4 0.069 11.6 14.1 1.1 1 0 0 1 1 1 0 Daxx Family CENP-T PF15511.1 EGC39154.1 - 1.6 7.9 11.9 2.3 7.3 8.3 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Astro_capsid PF03115.9 EGC39154.1 - 5.6 5.0 8.8 9 4.4 6.1 1.3 1 0 0 1 1 1 0 Astrovirus capsid protein precursor Herpes_DNAp_acc PF04929.7 EGC39154.1 - 7.1 5.4 9.5 11 4.8 6.6 1.2 1 0 0 1 1 1 0 Herpes DNA replication accessory factor dUTPase PF00692.14 EGC39155.1 - 0.0015 17.9 0.0 0.0024 17.3 0.0 1.3 1 0 0 1 1 1 1 dUTPase VCBS PF13517.1 EGC39156.1 - 3.6e-30 104.1 33.9 6.1e-11 42.5 1.8 6.0 3 1 3 6 6 6 6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella FG-GAP PF01839.18 EGC39156.1 - 8e-22 76.3 11.9 0.00019 21.0 0.2 7.7 7 0 0 7 7 7 7 FG-GAP repeat UnbV_ASPIC PF07593.7 EGC39156.1 - 2.7e-13 49.3 0.0 5.2e-13 48.4 0.0 1.5 1 0 0 1 1 1 1 ASPIC and UnbV SHS2_Rpb7-N PF03876.12 EGC39157.1 - 4.8e-08 33.0 0.0 8e-08 32.3 0.0 1.4 1 0 0 1 1 1 1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 RNA_pol_Rbc25 PF08292.7 EGC39157.1 - 0.0021 18.2 0.3 0.0044 17.2 0.1 1.6 2 0 0 2 2 2 1 RNA polymerase III subunit Rpc25 F_actin_cap_B PF01115.12 EGC39158.1 - 4e-103 343.8 0.3 4.7e-103 343.5 0.2 1.0 1 0 0 1 1 1 1 F-actin capping protein, beta subunit Cellulase PF00150.13 EGC39159.1 - 7.4e-29 100.8 1.4 1.6e-28 99.7 1.0 1.6 1 1 0 1 1 1 1 Cellulase (glycosyl hydrolase family 5) ASF1_hist_chap PF04729.8 EGC39160.1 - 3.3e-66 221.6 0.1 3.7e-66 221.5 0.1 1.0 1 0 0 1 1 1 1 ASF1 like histone chaperone Isy1 PF06246.7 EGC39161.1 - 9.7e-89 297.1 19.7 1.8e-88 296.2 13.6 1.4 1 1 0 1 1 1 1 Isy1-like splicing family DUF3568 PF12092.3 EGC39161.1 - 3.1 7.5 6.5 23 4.6 2.4 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF3568) FG-GAP PF01839.18 EGC39162.1 - 2.1e-23 81.3 33.9 0.0018 17.9 0.2 7.5 7 0 0 7 7 7 7 FG-GAP repeat VCBS PF13517.1 EGC39162.1 - 1.2e-17 63.9 42.9 6.1e-06 26.5 1.3 5.4 2 2 3 5 5 5 5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella EGF_2 PF07974.8 EGC39162.1 - 1.3e-11 44.4 71.4 0.0017 18.5 8.0 4.5 4 0 0 4 4 4 4 EGF-like domain TcdB_toxin_midN PF12256.3 EGC39162.1 - 7.5e-06 25.5 8.8 0.048 13.0 0.0 5.2 3 1 2 5 5 5 2 Insecticide toxin TcdB middle/N-terminal region hEGF PF12661.2 EGC39162.1 - 0.0024 17.8 27.5 0.068 13.2 1.1 4.4 4 0 0 4 4 4 3 Human growth factor-like EGF ATG22 PF11700.3 EGC39162.1 - 0.033 12.6 0.1 1.1 7.6 0.1 2.1 2 0 0 2 2 2 0 Vacuole effluxer Atg22 like EphA2_TM PF14575.1 EGC39162.1 - 0.087 13.2 0.0 0.17 12.2 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain EGF PF00008.22 EGC39162.1 - 0.22 11.5 54.3 0.73 9.8 5.2 4.7 4 0 0 4 4 4 0 EGF-like domain Laminin_EGF PF00053.19 EGC39162.1 - 5 7.1 60.2 0.64 9.9 7.1 4.4 2 1 2 4 4 4 0 Laminin EGF-like (Domains III and V) Peptidase_C12 PF01088.16 EGC39163.1 - 8.8e-70 234.2 1.6 1e-69 234.0 0.0 1.9 2 1 0 2 2 2 1 Ubiquitin carboxyl-terminal hydrolase, family 1 T2SF PF00482.18 EGC39163.1 - 0.02 14.7 0.2 0.037 13.9 0.1 1.5 1 0 0 1 1 1 0 Type II secretion system (T2SS), protein F Clp1 PF06807.9 EGC39164.1 - 6.2e-44 150.1 0.0 8.5e-44 149.6 0.0 1.2 1 0 0 1 1 1 1 Pre-mRNA cleavage complex II protein Clp1 MobB PF03205.9 EGC39164.1 - 4.6e-15 55.5 0.0 7.3e-15 54.9 0.0 1.3 1 0 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_10 PF12846.2 EGC39164.1 - 0.018 14.5 0.0 0.024 14.0 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_29 PF13555.1 EGC39164.1 - 0.054 13.0 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ATP_bind_1 PF03029.12 EGC39164.1 - 0.057 12.9 0.0 0.11 12.0 0.0 1.4 1 0 0 1 1 1 0 Conserved hypothetical ATP binding protein CbiA PF01656.18 EGC39164.1 - 0.098 12.0 0.0 0.2 11.0 0.0 1.5 1 1 0 1 1 1 0 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_17 PF13207.1 EGC39164.1 - 0.11 13.3 0.0 0.25 12.1 0.0 1.6 1 0 0 1 1 1 0 AAA domain ParA PF10609.4 EGC39165.1 - 2.2e-37 126.7 0.5 6.6e-37 125.2 0.3 1.8 2 0 0 2 2 2 1 ParA/MinD ATPase like CbiA PF01656.18 EGC39165.1 - 1.4e-13 50.7 0.0 1.9e-13 50.2 0.0 1.2 1 0 0 1 1 1 1 CobQ/CobB/MinD/ParA nucleotide binding domain AAA_31 PF13614.1 EGC39165.1 - 2.8e-06 27.3 0.0 1.5e-05 24.9 0.0 2.0 1 1 0 1 1 1 1 AAA domain ArsA_ATPase PF02374.10 EGC39165.1 - 7e-06 25.3 0.1 0.00013 21.1 0.0 2.2 2 0 0 2 2 2 1 Anion-transporting ATPase MipZ PF09140.6 EGC39165.1 - 0.00012 21.2 0.0 0.00046 19.3 0.0 1.8 1 1 0 1 1 1 1 ATPase MipZ DUF258 PF03193.11 EGC39165.1 - 0.00085 18.5 0.0 0.0018 17.4 0.0 1.5 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Fer4_NifH PF00142.13 EGC39165.1 - 0.0036 16.5 0.0 0.12 11.5 0.0 2.6 2 1 1 3 3 3 1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family AAA_25 PF13481.1 EGC39165.1 - 0.0041 16.5 0.0 0.0065 15.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_26 PF13500.1 EGC39165.1 - 0.0058 16.2 0.0 0.85 9.1 0.0 2.3 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC39165.1 - 0.1 13.4 0.1 0.19 12.5 0.0 1.7 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGC39165.1 - 0.11 12.0 0.0 0.27 10.7 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ArgK PF03308.11 EGC39165.1 - 0.11 11.2 0.0 0.17 10.6 0.0 1.2 1 0 0 1 1 1 0 ArgK protein Zn_Tnp_IS1595 PF12760.2 EGC39165.1 - 0.27 11.0 0.0 0.27 11.0 0.0 2.1 3 0 0 3 3 3 0 Transposase zinc-ribbon domain Pkinase PF00069.20 EGC39166.1 - 7.8e-32 110.4 3.0 3.5e-22 78.8 1.4 3.1 4 0 0 4 4 4 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39166.1 - 6e-17 61.5 0.1 9e-09 34.7 0.3 2.6 2 0 0 2 2 2 2 Protein tyrosine kinase zf-CCCH PF00642.19 EGC39168.1 - 2.4e-09 36.6 14.5 1e-06 28.2 0.5 3.3 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Secretin_N_2 PF07655.8 EGC39169.1 - 0.036 14.4 10.6 0.043 14.2 7.3 1.2 1 0 0 1 1 1 0 Secretin N-terminal domain DUF1570 PF07607.6 EGC39169.1 - 0.095 12.6 0.7 0.12 12.4 0.5 1.2 1 1 0 1 1 1 0 Protein of unknown function (DUF1570) CENP-R PF06729.7 EGC39169.1 - 0.1 12.2 4.6 0.13 11.9 3.2 1.1 1 0 0 1 1 1 0 Kinetochore component, CENP-R SPX PF03105.14 EGC39169.1 - 0.11 12.2 9.1 0.11 12.2 6.3 1.1 1 0 0 1 1 1 0 SPX domain POX PF07526.6 EGC39169.1 - 0.32 11.2 3.4 0.34 11.1 2.4 1.2 1 0 0 1 1 1 0 Associated with HOX CDK2AP PF09806.4 EGC39169.1 - 0.43 10.8 7.1 0.5 10.5 4.9 1.1 1 0 0 1 1 1 0 Cyclin-dependent kinase 2-associated protein CWC25 PF12542.3 EGC39169.1 - 1.1 9.7 11.4 2.3 8.7 8.0 1.5 1 1 0 1 1 1 0 Pre-mRNA splicing factor DUF4175 PF13779.1 EGC39169.1 - 1.2 6.8 9.3 1.4 6.5 6.4 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) Prothymosin PF03247.9 EGC39169.1 - 2.2 8.4 8.9 2.8 8.1 6.1 1.3 1 0 0 1 1 1 0 Prothymosin/parathymosin family Pex14_N PF04695.8 EGC39169.1 - 3.2 7.8 8.2 4.1 7.4 5.7 1.3 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Ndc1_Nup PF09531.5 EGC39169.1 - 8.4 4.6 7.2 9.4 4.5 5.0 1.0 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup NTF2 PF02136.15 EGC39170.1 - 3.6e-28 98.3 0.0 4e-28 98.1 0.0 1.0 1 0 0 1 1 1 1 Nuclear transport factor 2 (NTF2) domain dCMP_cyt_deam_1 PF00383.17 EGC39171.1 - 5.1e-14 51.7 0.3 8.5e-14 51.0 0.2 1.3 1 0 0 1 1 1 1 Cytidine and deoxycytidylate deaminase zinc-binding region zf-TFIIB PF13453.1 EGC39171.1 - 0.03 13.5 0.1 0.07 12.3 0.0 1.6 1 0 0 1 1 1 0 Transcription factor zinc-finger DUF2039 PF10217.4 EGC39171.1 - 0.12 12.4 2.5 0.26 11.3 1.7 1.7 1 1 0 1 1 1 0 Uncharacterized conserved protein (DUF2039) zf-RING_2 PF13639.1 EGC39171.1 - 0.66 9.8 4.0 3.7 7.4 0.3 2.8 2 1 1 3 3 3 0 Ring finger domain DUF3023 PF11224.3 EGC39172.1 - 0.009 15.6 2.7 0.009 15.6 1.9 2.1 1 1 1 2 2 2 1 Protein of unknown function (DUF3023) DUF1180 PF06679.7 EGC39173.1 - 0.046 13.5 1.2 0.1 12.4 0.5 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1180) ODV-E18 PF10717.4 EGC39173.1 - 0.092 12.1 1.5 0.14 11.6 0.1 1.9 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 DUF1049 PF06305.6 EGC39174.1 - 0.0071 15.7 1.7 3.1 7.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1049) SpoVA PF03862.8 EGC39174.1 - 0.015 15.3 1.5 0.024 14.7 1.0 1.3 1 0 0 1 1 1 0 SpoVA protein PrcB_C PF14343.1 EGC39174.1 - 0.11 12.2 0.3 0.27 10.9 0.2 1.6 1 0 0 1 1 1 0 PrcB C-terminal P5CR_dimer PF14748.1 EGC39175.1 - 2.8e-25 88.4 0.6 4.6e-25 87.6 0.4 1.4 1 0 0 1 1 1 1 Pyrroline-5-carboxylate reductase dimerisation F420_oxidored PF03807.12 EGC39175.1 - 2.3e-16 59.9 0.3 4.8e-16 58.9 0.2 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent NAD_Gly3P_dh_N PF01210.18 EGC39175.1 - 4.2e-09 36.3 0.1 8e-09 35.4 0.1 1.5 1 0 0 1 1 1 1 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus ApbA PF02558.11 EGC39175.1 - 2.8e-06 26.8 0.5 2.8e-05 23.5 0.1 2.3 2 0 0 2 2 2 1 Ketopantoate reductase PanE/ApbA NAD_binding_2 PF03446.10 EGC39175.1 - 2.4e-05 24.2 0.1 6.5e-05 22.8 0.0 1.8 2 0 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase RhoGAP PF00620.22 EGC39176.1 - 2.8e-19 69.2 0.0 4e-18 65.4 0.0 2.4 2 1 0 2 2 2 1 RhoGAP domain TIP41 PF04176.8 EGC39178.1 - 8.1e-70 233.7 0.8 1.3e-69 233.1 0.6 1.3 1 0 0 1 1 1 1 TIP41-like family ACPS PF01648.15 EGC39180.1 - 1.1e-14 54.2 0.1 6.3e-14 51.7 0.0 2.2 2 0 0 2 2 2 1 4'-phosphopantetheinyl transferase superfamily DUF3496 PF12001.3 EGC39180.1 - 0.075 13.2 1.4 0.3 11.3 0.9 2.1 2 1 0 2 2 2 0 Domain of unknown function (DUF3496) XhlA PF10779.4 EGC39180.1 - 2.9 7.8 6.2 40 4.2 2.7 3.3 2 1 1 3 3 3 0 Haemolysin XhlA TMEM164 PF14808.1 EGC39181.1 - 7.5e-06 25.3 11.8 0.00012 21.4 6.9 2.5 2 1 1 3 3 3 2 TMEM164 family Intg_mem_TP0381 PF09529.5 EGC39181.1 - 0.37 10.0 21.2 0.091 11.9 11.8 2.1 2 1 0 2 2 2 0 Integral membrane protein (intg_mem_TP0381) Exo_endo_phos PF03372.18 EGC39182.1 - 2.1e-09 37.7 0.0 2.8e-09 37.2 0.0 1.2 1 0 0 1 1 1 1 Endonuclease/Exonuclease/phosphatase family ABC2_membrane PF01061.19 EGC39183.1 - 1.6e-86 288.7 64.8 2.1e-47 161.0 14.7 3.0 3 0 0 3 3 3 2 ABC-2 type transporter ABC_tran PF00005.22 EGC39183.1 - 6.6e-39 133.3 0.0 2.5e-19 69.9 0.0 2.6 2 0 0 2 2 2 2 ABC transporter PDR_CDR PF06422.7 EGC39183.1 - 1.2e-21 76.2 12.6 1.4e-20 72.8 0.0 4.1 4 0 0 4 4 3 2 CDR ABC transporter ABC_trans_N PF14510.1 EGC39183.1 - 7.3e-12 45.2 0.0 1.6e-11 44.1 0.0 1.6 1 0 0 1 1 1 1 ABC-transporter extracellular N-terminal DUF258 PF03193.11 EGC39183.1 - 1.6e-06 27.3 0.0 0.00029 20.0 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC39183.1 - 1.7e-06 27.4 0.5 0.0031 17.0 0.1 2.9 3 0 0 3 3 2 2 P-loop containing region of AAA domain AAA_25 PF13481.1 EGC39183.1 - 3.4e-05 23.3 0.2 0.0018 17.7 0.1 2.5 2 0 0 2 2 2 1 AAA domain ABC2_membrane_3 PF12698.2 EGC39183.1 - 4.5e-05 22.6 64.2 0.01 14.9 14.9 4.4 2 2 2 4 4 4 2 ABC-2 family transporter protein AAA_22 PF13401.1 EGC39183.1 - 6.5e-05 23.0 1.2 0.13 12.4 0.1 3.1 3 1 0 3 3 2 2 AAA domain cobW PF02492.14 EGC39183.1 - 0.00057 19.3 0.3 0.14 11.6 0.0 2.4 2 0 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGC39183.1 - 0.0015 18.4 0.0 0.71 9.7 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF3377 PF11857.3 EGC39183.1 - 0.002 17.7 0.1 0.0094 15.5 0.0 2.1 1 0 0 1 1 1 1 Domain of unknown function (DUF3377) Arch_ATPase PF01637.13 EGC39183.1 - 0.0024 17.6 0.0 3.4 7.3 0.0 3.0 2 0 0 2 2 2 2 Archaeal ATPase AAA_16 PF13191.1 EGC39183.1 - 0.0037 17.2 0.0 0.61 10.0 0.0 2.5 2 0 0 2 2 2 1 AAA ATPase domain MMR_HSR1 PF01926.18 EGC39183.1 - 0.0065 16.4 0.0 3.2 7.7 0.0 2.7 2 0 0 2 2 2 1 50S ribosome-binding GTPase AAA_17 PF13207.1 EGC39183.1 - 0.013 16.2 0.2 0.54 11.0 0.0 3.0 3 0 0 3 3 2 0 AAA domain Peptidase_M56 PF05569.6 EGC39183.1 - 0.022 13.7 0.2 0.64 8.9 0.1 2.7 2 0 0 2 2 2 0 BlaR1 peptidase M56 SbcCD_C PF13558.1 EGC39183.1 - 0.023 14.6 0.0 0.29 11.0 0.0 2.4 2 0 0 2 2 2 0 Putative exonuclease SbcCD, C subunit AAA_19 PF13245.1 EGC39183.1 - 0.037 13.7 0.0 9.7 6.0 0.0 2.4 2 0 0 2 2 2 0 Part of AAA domain FtsK_SpoIIIE PF01580.13 EGC39183.1 - 0.043 13.2 0.1 5.8 6.3 0.0 2.3 2 0 0 2 2 2 0 FtsK/SpoIIIE family Miro PF08477.8 EGC39183.1 - 0.045 14.2 0.0 2.5 8.6 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein AAA PF00004.24 EGC39183.1 - 0.055 13.6 1.1 5.3 7.2 0.1 3.1 2 1 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGC39183.1 - 0.057 13.0 0.3 5.5 6.6 0.2 2.5 2 0 0 2 2 2 0 NACHT domain UPF0079 PF02367.12 EGC39183.1 - 0.061 12.9 0.3 0.57 9.8 0.1 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_21 PF13304.1 EGC39183.1 - 0.08 12.8 0.1 0.44 10.4 0.0 4.8 5 0 0 5 5 5 0 AAA domain TMEM154 PF15102.1 EGC39183.1 - 0.12 12.0 1.6 0.32 10.6 0.8 1.9 2 0 0 2 2 2 0 TMEM154 protein family AAA_18 PF13238.1 EGC39183.1 - 0.13 12.5 4.1 0.85 9.9 0.0 3.5 3 0 0 3 3 3 0 AAA domain PduV-EutP PF10662.4 EGC39183.1 - 0.17 11.3 1.1 1.2 8.5 0.2 2.3 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_28 PF13521.1 EGC39183.1 - 0.2 11.6 0.5 0.57 10.1 0.3 1.8 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC39183.1 - 0.32 10.5 0.2 4.9 6.6 0.1 2.2 2 0 0 2 2 2 0 AAA domain AAA_10 PF12846.2 EGC39183.1 - 0.33 10.3 1.5 12 5.2 0.0 2.8 3 0 0 3 3 3 0 AAA-like domain FNIP PF05725.7 EGC39185.1 - 1.4e-71 236.2 53.8 2.9e-13 49.5 0.9 9.9 4 2 6 11 11 11 11 FNIP Repeat RVT_1 PF00078.22 EGC39187.1 - 7.9e-37 126.6 0.2 7.9e-37 126.6 0.2 2.4 3 0 0 3 3 3 1 Reverse transcriptase (RNA-dependent DNA polymerase) LEAP-2 PF07359.6 EGC39188.1 - 0.55 9.9 14.4 9.9 5.8 0.3 4.0 3 0 0 3 3 3 0 Liver-expressed antimicrobial peptide 2 precursor (LEAP-2) GWT1 PF06423.7 EGC39189.1 - 1.5e-32 112.5 11.1 1.5e-32 112.5 7.7 3.0 3 1 0 3 3 3 1 GWT1 UPF0233 PF06781.7 EGC39189.1 - 3e-05 23.5 0.6 0.00032 20.2 0.0 2.8 2 0 0 2 2 2 1 Uncharacterised protein family (UPF0233) Secretin_N_2 PF07655.8 EGC39189.1 - 0.075 13.4 0.0 0.14 12.5 0.0 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain Far-17a_AIG1 PF04750.9 EGC39190.1 - 1.5e-29 102.5 15.4 1.3e-21 76.7 5.2 2.1 2 0 0 2 2 2 2 FAR-17a/AIG1-like protein TraS PF10624.4 EGC39190.1 - 3.6 7.1 8.0 5.9 6.4 4.6 1.9 2 0 0 2 2 2 0 Plasmid conjugative transfer entry exclusion protein TraS Pex2_Pex12 PF04757.9 EGC39191.1 - 2.8e-72 242.8 13.6 3.6e-72 242.4 9.4 1.1 1 0 0 1 1 1 1 Pex2 / Pex12 amino terminal region zf-C3HC4_2 PF13923.1 EGC39191.1 - 4.9e-06 26.4 6.6 8.1e-06 25.7 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC39191.1 - 0.00065 19.3 3.6 0.0011 18.6 2.5 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC39191.1 - 0.0027 17.5 4.6 0.0059 16.4 3.2 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC39191.1 - 0.053 13.2 5.3 0.11 12.1 3.7 1.6 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC39191.1 - 0.75 9.7 7.9 1.4 8.8 5.5 1.4 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING CoaE PF01121.15 EGC39192.1 - 9.8e-45 152.1 0.0 1.2e-44 151.8 0.0 1.0 1 0 0 1 1 1 1 Dephospho-CoA kinase AAA_18 PF13238.1 EGC39192.1 - 2.3e-07 31.1 3.3 6.8e-07 29.6 1.2 2.3 1 1 1 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC39192.1 - 3e-06 28.0 1.1 1.1e-05 26.2 0.8 2.1 1 1 0 1 1 1 1 AAA domain Cytidylate_kin2 PF13189.1 EGC39192.1 - 1.1e-05 25.4 0.2 1.5e-05 24.9 0.2 1.3 1 0 0 1 1 1 1 Cytidylate kinase-like family AAA_28 PF13521.1 EGC39192.1 - 0.00026 21.0 0.0 0.0024 17.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC39192.1 - 0.0031 17.4 0.1 0.088 12.6 0.1 2.3 1 1 0 1 1 1 1 AAA domain FEZ PF07763.8 EGC39192.1 - 0.0041 16.8 1.6 0.0065 16.2 1.1 1.4 1 0 0 1 1 1 1 FEZ-like protein Aminotran_4 PF01063.14 EGC39193.1 - 3.1e-27 95.5 0.0 3.8e-27 95.2 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class IV Pkinase PF00069.20 EGC39194.1 - 5.7e-73 245.2 0.0 1.6e-72 243.7 0.0 1.8 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39194.1 - 2.2e-49 167.8 0.0 3.9e-49 167.0 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC39194.1 - 0.0024 16.8 0.0 0.0061 15.5 0.0 1.6 1 0 0 1 1 1 1 Kinase-like SLBP_RNA_bind PF15247.1 EGC39194.1 - 0.038 13.7 0.5 0.1 12.3 0.4 1.7 1 0 0 1 1 1 0 Histone RNA hairpin-binding protein RNA-binding domain V-ATPase_H_C PF11698.3 EGC39194.1 - 0.11 12.3 4.0 3 7.7 0.5 3.1 2 1 1 3 3 3 0 V-ATPase subunit H CSTF2_hinge PF14327.1 EGC39194.1 - 0.19 11.8 7.7 0.063 13.3 0.4 3.3 3 0 0 3 3 3 0 Hinge domain of cleavage stimulation factor subunit 2 RTTN_N PF14726.1 EGC39194.1 - 0.36 11.4 3.0 14 6.3 0.1 3.9 2 1 2 4 4 4 0 Rotatin, an armadillo repeat protein, centriole functioning CDC50 PF03381.10 EGC39195.1 - 4.1e-89 298.4 1.4 4.1e-89 298.4 1.0 1.8 1 1 1 2 2 2 1 LEM3 (ligand-effect modulator 3) family / CDC50 family UPF0233 PF06781.7 EGC39195.1 - 0.00089 18.8 1.2 1.2 8.7 0.2 2.4 2 0 0 2 2 2 2 Uncharacterised protein family (UPF0233) NfeD PF01957.13 EGC39195.1 - 0.066 13.3 0.7 3.7 7.6 0.1 2.2 2 0 0 2 2 2 0 NfeD-like C-terminal, partner-binding Claudin_2 PF13903.1 EGC39195.1 - 0.12 12.0 0.1 2.9 7.5 0.0 2.3 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction DUF3185 PF11381.3 EGC39195.1 - 0.12 12.1 6.0 3.2 7.5 0.6 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3185) IncA PF04156.9 EGC39195.1 - 0.39 10.2 1.8 3.3 7.2 0.7 2.0 2 0 0 2 2 2 0 IncA protein adh_short PF00106.20 EGC39196.1 - 4.1e-21 75.6 0.0 5.7e-21 75.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC39196.1 - 3.5e-10 40.0 0.0 4.7e-10 39.6 0.0 1.2 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC39196.1 - 1.2e-07 31.5 0.1 2e-07 30.8 0.1 1.3 1 0 0 1 1 1 1 KR domain Eno-Rase_NADH_b PF12242.3 EGC39196.1 - 0.033 13.9 0.3 0.075 12.8 0.2 1.6 1 0 0 1 1 1 0 NAD(P)H binding domain of trans-2-enoyl-CoA reductase Epimerase PF01370.16 EGC39196.1 - 0.039 13.3 0.0 0.065 12.6 0.0 1.4 1 0 0 1 1 1 0 NAD dependent epimerase/dehydratase family NAD_binding_10 PF13460.1 EGC39196.1 - 0.07 13.1 0.1 0.12 12.3 0.1 1.4 1 0 0 1 1 1 0 NADH(P)-binding 2-Hacid_dh_C PF02826.14 EGC39196.1 - 0.099 11.7 0.2 0.21 10.7 0.1 1.6 1 1 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain NDT80_PhoG PF05224.7 EGC39197.1 - 3.4e-20 72.8 0.5 3.4e-20 72.8 0.4 5.4 2 2 2 4 4 4 1 NDT80 / PhoG like DNA-binding family Peptidase_S74 PF13884.1 EGC39197.1 - 3e-10 40.0 0.3 7.2e-10 38.8 0.2 1.7 1 0 0 1 1 1 1 Chaperone of endosialidase MRF_C1 PF13887.1 EGC39197.1 - 5.9e-07 28.3 0.4 1.3e-06 27.3 0.3 1.6 1 0 0 1 1 1 1 Myelin gene regulatory factor -C-terminal domain 1 DUF3439 PF11921.3 EGC39197.1 - 8 6.2 9.3 14 5.4 2.2 3.0 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF4279 PF14106.1 EGC39198.1 - 0.01 15.6 0.6 0.01 15.6 0.4 1.9 1 1 1 2 2 2 0 Domain of unknown function (DUF4279) Y_phosphatase3 PF13350.1 EGC39198.1 - 0.25 11.6 4.4 0.23 11.7 1.8 1.7 1 1 1 2 2 2 0 Tyrosine phosphatase family CTP_transf_2 PF01467.21 EGC39198.1 - 0.33 10.9 4.0 0.31 11.0 0.4 2.2 1 1 1 2 2 2 0 Cytidylyltransferase CPSase_L_D3 PF02787.14 EGC39198.1 - 0.46 10.2 7.5 0.066 12.9 2.1 1.8 2 0 0 2 2 2 0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain Leu_zip PF15294.1 EGC39198.1 - 1.1 8.2 27.1 0.04 13.0 8.9 2.5 1 1 2 3 3 3 0 Leucine zipper TPR_MLP1_2 PF07926.7 EGC39198.1 - 2.7 7.7 30.2 6.2 6.5 12.1 3.4 1 1 1 2 2 2 0 TPR/MLP1/MLP2-like protein Tropomyosin_1 PF12718.2 EGC39198.1 - 3.5 7.4 23.3 13 5.6 14.8 2.4 1 1 0 1 1 1 0 Tropomyosin like NBP1 PF08537.5 EGC39198.1 - 3.6 6.7 24.9 0.062 12.4 3.0 2.6 1 1 2 3 3 3 0 Fungal Nap binding protein NBP1 FUSC-like PF12805.2 EGC39198.1 - 5.9 5.7 14.6 7.6 5.3 10.1 1.1 1 0 0 1 1 1 0 FUSC-like inner membrane protein yccS DUF4140 PF13600.1 EGC39198.1 - 7.3 7.0 11.1 1.8 9.0 0.2 3.1 2 1 1 3 3 3 0 N-terminal domain of unknown function (DUF4140) Cep57_CLD_2 PF14197.1 EGC39198.1 - 7.8 6.5 19.9 0.13 12.2 2.4 3.5 3 1 0 3 3 3 0 Centrosome localisation domain of PPC89 bZIP_1 PF00170.16 EGC39198.1 - 8.8 6.3 19.5 3.3 7.7 0.1 3.8 3 1 1 4 4 4 0 bZIP transcription factor Ank_2 PF12796.2 EGC39199.1 - 1.2e-22 80.0 3.5 3.2e-08 33.7 0.0 4.0 2 1 2 4 4 4 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC39199.1 - 1.9e-15 56.8 1.2 1e-05 25.9 0.0 5.1 1 1 4 5 5 5 4 Ankyrin repeats (many copies) Ank PF00023.25 EGC39199.1 - 8.2e-15 53.7 0.2 7.2e-07 28.7 0.0 4.6 4 0 0 4 4 4 2 Ankyrin repeat Ank_5 PF13857.1 EGC39199.1 - 1.5e-13 50.4 1.2 2.7e-06 27.4 0.0 5.3 3 2 2 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC39199.1 - 8.9e-12 44.0 0.3 0.00072 19.5 0.0 5.0 4 0 0 4 4 4 2 Ankyrin repeat Mucin PF01456.12 EGC39199.1 - 4.6 7.0 11.8 9.9 5.9 8.2 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Cnd3 PF12719.2 EGC39200.1 - 1.1e-37 129.6 7.8 1.1e-37 129.6 5.4 3.7 3 1 1 4 4 4 2 Nuclear condensing complex subunits, C-term domain HEAT_2 PF13646.1 EGC39200.1 - 1.8e-07 31.3 0.0 0.00026 21.1 0.0 4.1 3 2 2 5 5 5 2 HEAT repeats DNA_binding_1 PF01035.15 EGC39202.1 - 5.3e-22 77.3 0.0 8e-22 76.7 0.0 1.2 1 0 0 1 1 1 1 6-O-methylguanine DNA methyltransferase, DNA binding domain Methyltransf_1N PF02870.10 EGC39202.1 - 0.079 13.5 0.0 0.18 12.4 0.0 1.6 2 0 0 2 2 2 0 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain EST1 PF10374.4 EGC39202.1 - 0.45 10.5 3.3 0.16 12.0 0.2 1.8 2 1 0 2 2 2 0 Telomerase activating protein Est1 FERM_N PF09379.5 EGC39203.1 - 0.007 16.4 0.0 0.18 11.8 0.0 2.8 2 0 0 2 2 2 1 FERM N-terminal domain IncA PF04156.9 EGC39203.1 - 0.022 14.3 71.7 0.053 13.1 3.8 4.6 1 1 2 4 4 4 0 IncA protein Myosin_tail_1 PF01576.14 EGC39203.1 - 0.065 10.9 73.8 0.11 10.1 25.6 2.1 1 1 1 2 2 2 0 Myosin tail Cyd_oper_YbgE PF09600.5 EGC39203.1 - 0.24 11.6 0.0 0.44 10.7 0.0 1.3 1 0 0 1 1 1 0 Cyd operon protein YbgE (Cyd_oper_YbgE) APG12 PF04110.8 EGC39203.1 - 2.5 8.3 6.8 81 3.5 0.0 4.0 4 0 0 4 4 4 0 Ubiquitin-like autophagy protein Apg12 Reo_sigmaC PF04582.7 EGC39203.1 - 4.9 6.2 18.3 1.8 7.6 1.5 3.5 1 1 3 4 4 4 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGC39203.1 - 8.6 6.2 76.0 2.1 8.1 6.4 5.8 1 1 4 5 5 5 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Pkinase PF00069.20 EGC39204.1 - 1e-53 182.1 0.2 3.3e-53 180.4 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39204.1 - 1.6e-51 174.8 0.0 2.6e-51 174.1 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase RGS PF00615.14 EGC39204.1 - 8.3e-14 51.7 3.4 4.2e-13 49.4 2.4 2.3 1 0 0 1 1 1 1 Regulator of G protein signaling domain APH PF01636.18 EGC39204.1 - 0.01 15.5 0.0 0.5 10.0 0.1 2.2 2 0 0 2 2 2 0 Phosphotransferase enzyme family Trypan_PARP PF05887.6 EGC39204.1 - 0.35 10.6 4.8 0.95 9.2 3.3 1.7 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) FNIP PF05725.7 EGC39205.1 - 1.4e-89 293.8 39.9 4.7e-16 58.4 2.4 7.1 5 1 1 7 7 7 7 FNIP Repeat DUF1769 PF08588.5 EGC39205.1 - 1e-06 28.6 14.3 1.3 9.0 0.0 7.0 5 3 3 8 8 8 5 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC39205.1 - 0.0001 22.0 1.2 0.16 11.6 0.0 2.9 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) Nop16 PF09420.5 EGC39206.1 - 5.2e-17 62.4 7.9 9.1e-14 51.8 1.4 3.3 2 2 1 3 3 3 2 Ribosome biogenesis protein Nop16 DUF4589 PF15252.1 EGC39206.1 - 0.0032 17.3 5.4 0.0039 17.0 3.8 1.3 1 0 0 1 1 1 1 Domain of unknown function (DUF4589) Mucin PF01456.12 EGC39206.1 - 0.063 13.0 7.4 0.087 12.6 5.1 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein DUF2407_C PF13373.1 EGC39206.1 - 0.29 11.0 3.7 0.55 10.1 2.6 1.4 1 0 0 1 1 1 0 DUF2407 C-terminal domain Selenoprotein_S PF06936.6 EGC39206.1 - 0.95 8.9 12.0 1.8 8.0 8.3 1.6 1 0 0 1 1 1 0 Selenoprotein S (SelS) DUF4407 PF14362.1 EGC39206.1 - 2.9 6.7 6.9 4.1 6.2 4.8 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4407) RBP_receptor PF14752.1 EGC39206.1 - 5.8 5.1 7.0 10 4.3 4.8 1.3 1 0 0 1 1 1 0 Retinol binding protein receptor Rhodanese PF00581.15 EGC39208.1 - 3.5e-11 43.4 0.0 5.3e-11 42.8 0.0 1.3 1 0 0 1 1 1 1 Rhodanese-like domain AAA PF00004.24 EGC39209.1 - 5.7e-39 133.3 0.0 9.1e-39 132.6 0.0 1.3 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGC39209.1 - 1.3e-07 30.9 0.0 2.1e-07 30.2 0.0 1.3 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus TIP49 PF06068.8 EGC39209.1 - 4.5e-05 22.3 0.2 0.00013 20.7 0.0 1.8 1 1 1 2 2 2 1 TIP49 C-terminus AAA_25 PF13481.1 EGC39209.1 - 5.2e-05 22.7 0.5 0.02 14.3 0.1 2.5 1 1 2 3 3 3 2 AAA domain AAA_22 PF13401.1 EGC39209.1 - 7.4e-05 22.9 0.7 0.011 15.8 0.1 2.5 1 1 1 2 2 2 1 AAA domain AAA_5 PF07728.9 EGC39209.1 - 8.3e-05 22.3 0.2 0.00077 19.1 0.2 2.3 1 1 0 1 1 1 1 AAA domain (dynein-related subfamily) Vps4_C PF09336.5 EGC39209.1 - 0.00015 21.5 0.0 0.00029 20.6 0.0 1.5 1 0 0 1 1 1 1 Vps4 C terminal oligomerisation domain AAA_17 PF13207.1 EGC39209.1 - 0.00083 20.1 0.2 0.0071 17.1 0.0 2.3 1 1 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC39209.1 - 0.003 17.8 0.0 0.0084 16.4 0.0 1.9 1 1 0 1 1 1 1 AAA domain Bac_DnaA PF00308.13 EGC39209.1 - 0.0034 17.0 0.1 0.041 13.5 0.1 2.1 1 1 0 1 1 1 1 Bacterial dnaA protein Mg_chelatase PF01078.16 EGC39209.1 - 0.0043 16.2 0.1 0.0089 15.2 0.1 1.5 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI AAA_2 PF07724.9 EGC39209.1 - 0.0045 16.9 0.0 0.012 15.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) IstB_IS21 PF01695.12 EGC39209.1 - 0.0053 16.1 0.0 0.0088 15.4 0.0 1.4 1 0 0 1 1 1 1 IstB-like ATP binding protein AAA_19 PF13245.1 EGC39209.1 - 0.006 16.2 0.2 0.036 13.8 0.1 2.1 2 0 0 2 2 2 1 Part of AAA domain Ribosomal_L50 PF10501.4 EGC39209.1 - 0.013 15.5 0.0 0.024 14.5 0.0 1.4 1 0 0 1 1 1 0 Ribosomal subunit 39S RNA_helicase PF00910.17 EGC39209.1 - 0.024 14.7 0.0 0.069 13.3 0.0 1.9 2 0 0 2 2 2 0 RNA helicase AAA_16 PF13191.1 EGC39209.1 - 0.044 13.7 0.1 0.14 12.1 0.1 2.0 1 1 0 1 1 1 0 AAA ATPase domain Guanylate_kin PF00625.16 EGC39209.1 - 0.049 13.0 0.1 0.13 11.6 0.0 1.7 2 0 0 2 2 2 0 Guanylate kinase AAA_24 PF13479.1 EGC39209.1 - 0.051 13.1 0.9 0.3 10.6 0.3 2.3 2 1 0 2 2 2 0 AAA domain Zeta_toxin PF06414.7 EGC39209.1 - 0.065 12.3 0.1 0.22 10.5 0.0 1.8 2 0 0 2 2 2 0 Zeta toxin AAA_11 PF13086.1 EGC39209.1 - 0.1 12.1 0.0 0.12 11.9 0.0 1.4 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGC39209.1 - 0.11 12.4 0.0 0.24 11.2 0.0 1.7 2 0 0 2 2 2 0 AAA domain SKI PF01202.17 EGC39209.1 - 0.13 12.1 0.2 0.33 10.8 0.1 1.7 1 0 0 1 1 1 0 Shikimate kinase zf-UBP PF02148.14 EGC39212.1 - 0.057 13.5 0.0 0.1 12.7 0.0 1.4 1 0 0 1 1 1 0 Zn-finger in ubiquitin-hydrolases and other protein DUF4435 PF14491.1 EGC39212.1 - 0.77 9.5 10.4 1.8 8.3 1.6 2.5 2 1 1 3 3 3 0 Protein of unknown function (DUF4435) SET PF00856.23 EGC39214.1 - 4.2e-28 98.6 0.2 2.1e-27 96.3 0.2 1.8 1 1 0 1 1 1 1 SET domain Ricin_B_lectin PF00652.17 EGC39214.1 - 0.088 12.8 0.7 0.35 10.9 0.6 1.7 1 1 0 1 1 1 0 Ricin-type beta-trefoil lectin domain Histone PF00125.19 EGC39215.1 - 1.3e-32 111.7 0.2 2.3e-32 110.9 0.1 1.4 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC39215.1 - 9e-05 22.5 0.0 0.00014 21.9 0.0 1.3 1 0 0 1 1 1 1 Kinetochore component CENP-S CENP-T PF15511.1 EGC39215.1 - 0.02 14.1 0.1 0.04 13.1 0.0 1.4 1 1 0 1 1 1 0 Centromere kinetochore component CENP-T DUF573 PF04504.9 EGC39217.1 - 0.46 10.7 10.0 1.2 9.5 1.4 3.1 2 1 1 3 3 3 0 Protein of unknown function, DUF573 UPF0147 PF03685.8 EGC39217.1 - 1.5 8.7 9.4 1.3 8.9 0.8 3.7 1 1 4 5 5 5 0 Uncharacterised protein family (UPF0147) LMBR1 PF04791.11 EGC39217.1 - 2.1 6.8 9.7 0.46 9.0 2.5 1.9 1 1 0 2 2 2 0 LMBR1-like membrane protein DUF3314 PF11771.3 EGC39218.1 - 0.038 13.7 0.0 0.049 13.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3314) Snapin_Pallidin PF14712.1 EGC39219.1 - 0.095 13.0 0.2 0.14 12.4 0.2 1.3 1 0 0 1 1 1 0 Snapin/Pallidin Nic96 PF04097.9 EGC39221.1 - 1.9e-67 227.7 24.1 9e-67 225.5 16.7 2.0 1 1 0 1 1 1 1 Nup93/Nic96 AHSP PF09236.5 EGC39221.1 - 0.097 12.8 0.3 0.097 12.8 0.2 3.6 2 1 1 3 3 3 0 Alpha-haemoglobin stabilising protein DUF4512 PF14975.1 EGC39222.1 - 2.1 9.2 8.4 3.9 8.3 5.8 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4512) HABP4_PAI-RBP1 PF04774.10 EGC39222.1 - 2.1 8.8 8.8 3.2 8.2 6.1 1.2 1 0 0 1 1 1 0 Hyaluronan / mRNA binding family DAP_epimerase PF01678.14 EGC39223.1 - 1.5e-39 134.6 0.1 1.3e-24 86.4 0.0 2.3 2 0 0 2 2 2 2 Diaminopimelate epimerase Peptidase_M8 PF01457.11 EGC39224.1 - 2.6e-59 200.9 1.5 3.3e-59 200.6 1.1 1.1 1 0 0 1 1 1 1 Leishmanolysin AA_permease_2 PF13520.1 EGC39225.1 - 1.4e-41 142.4 34.8 1.9e-41 142.0 24.1 1.0 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC39225.1 - 3e-24 85.2 27.4 4e-24 84.7 19.0 1.2 1 0 0 1 1 1 1 Amino acid permease Dispanin PF04505.7 EGC39225.1 - 0.51 9.9 9.3 0.17 11.4 0.3 3.3 3 0 0 3 3 3 0 Interferon-induced transmembrane protein DUF4231 PF14015.1 EGC39225.1 - 2.5 8.1 5.6 76 3.3 0.0 3.9 4 0 0 4 4 4 0 Protein of unknown function (DUF4231) Abhydrolase_2 PF02230.11 EGC39226.1 - 8.7e-51 172.4 0.0 9.5e-51 172.2 0.0 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGC39226.1 - 7.1e-13 48.5 0.0 9.9e-13 48.0 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_6 PF12697.2 EGC39226.1 - 7.1e-09 35.8 0.0 0.00025 21.0 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family FSH1 PF03959.8 EGC39226.1 - 4e-07 29.6 0.0 1.1e-06 28.2 0.0 1.7 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_1 PF00561.15 EGC39226.1 - 0.00011 21.8 0.0 0.11 12.0 0.0 2.1 1 1 1 2 2 2 2 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC39226.1 - 0.00031 20.0 0.0 0.0076 15.4 0.0 2.2 2 0 0 2 2 2 1 Prolyl oligopeptidase family DUF2974 PF11187.3 EGC39226.1 - 0.0041 16.5 0.0 0.0066 15.8 0.0 1.5 1 1 0 1 1 1 1 Protein of unknown function (DUF2974) Cutinase PF01083.17 EGC39226.1 - 0.016 14.9 0.0 0.022 14.4 0.0 1.4 1 0 0 1 1 1 0 Cutinase Abhydrolase_3 PF07859.8 EGC39226.1 - 0.045 13.3 0.0 0.056 13.0 0.0 1.3 1 0 0 1 1 1 0 alpha/beta hydrolase fold Abhydrolase_4 PF08386.5 EGC39226.1 - 0.057 13.3 0.0 0.14 12.0 0.0 1.5 2 0 0 2 2 2 0 TAP-like protein Pkinase PF00069.20 EGC39227.1 - 1.5e-06 27.5 0.1 3.2e-05 23.2 0.1 2.2 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39227.1 - 1.7e-06 27.2 0.0 7.7e-05 21.8 0.0 2.2 2 0 0 2 2 2 2 Protein tyrosine kinase DUF4653 PF15546.1 EGC39227.1 - 0.057 12.6 0.3 0.13 11.5 0.2 1.5 1 1 0 1 1 1 0 Domain of unknown function (DUF4653) EphA2_TM PF14575.1 EGC39227.1 - 0.13 12.6 0.1 0.23 11.8 0.0 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Glyco_hydro_57 PF03065.10 EGC39228.1 - 3.6e-08 32.7 0.3 1.1e-07 31.1 0.2 2.0 1 1 0 1 1 1 1 Glycosyl hydrolase family 57 E2 PF08199.6 EGC39228.1 - 0.075 12.6 0.3 0.16 11.5 0.2 1.5 1 0 0 1 1 1 0 Bacteriophage E2-like protein Glycos_transf_1 PF00534.15 EGC39229.1 - 1.5e-29 102.5 0.2 2.4e-29 101.9 0.2 1.3 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_4 PF13692.1 EGC39229.1 - 6e-11 42.6 0.0 1.2e-10 41.6 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 Glyco_trans_1_2 PF13524.1 EGC39229.1 - 7e-06 26.2 0.0 1.4e-05 25.2 0.0 1.5 1 0 0 1 1 1 1 Glycosyl transferases group 1 SEN1_N PF12726.2 EGC39231.1 - 0.0061 14.6 0.2 0.0075 14.3 0.1 1.0 1 0 0 1 1 1 1 SEN1 N terminal DUF716 PF04819.7 EGC39231.1 - 0.032 13.6 0.0 0.04 13.3 0.0 1.0 1 0 0 1 1 1 0 Family of unknown function (DUF716) DUF2729 PF10870.3 EGC39231.1 - 0.084 12.6 0.7 0.18 11.5 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF2729) Ras PF00071.17 EGC39232.1 - 2.1e-51 173.5 0.0 2.6e-51 173.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39232.1 - 8.1e-18 65.0 0.0 1.4e-17 64.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39232.1 - 1.9e-11 43.4 0.0 2.6e-11 43.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC39232.1 - 2e-05 24.1 0.1 0.00038 19.9 0.0 2.2 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC39232.1 - 0.047 12.8 0.0 0.098 11.7 0.0 1.6 1 1 0 1 1 1 0 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGC39232.1 - 0.048 13.1 0.8 4.2 6.8 0.1 2.9 2 1 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation MMR_HSR1 PF01926.18 EGC39232.1 - 0.05 13.5 0.5 0.086 12.8 0.0 1.6 2 0 0 2 2 2 0 50S ribosome-binding GTPase SH3_1 PF00018.23 EGC39233.1 - 3.8e-27 93.4 4.6 4.9e-14 51.4 0.1 2.8 3 0 0 3 3 3 2 SH3 domain SH3_2 PF07653.12 EGC39233.1 - 4.3e-23 80.5 0.0 3e-12 45.8 0.0 2.4 2 0 0 2 2 2 2 Variant SH3 domain SH3_9 PF14604.1 EGC39233.1 - 5.1e-23 80.4 1.8 8.2e-11 41.3 0.0 3.3 3 0 0 3 3 3 2 Variant SH3 domain Glutaminase PF04960.10 EGC39233.1 - 1.4e-19 70.2 0.0 3e-19 69.1 0.0 1.5 1 0 0 1 1 1 1 Glutaminase CS PF04969.11 EGC39233.1 - 1.6e-09 38.1 0.4 4.8e-09 36.6 0.3 1.9 1 0 0 1 1 1 1 CS domain GalKase_gal_bdg PF10509.4 EGC39234.1 - 2.3e-21 74.7 0.1 4.1e-21 73.9 0.1 1.4 1 0 0 1 1 1 1 Galactokinase galactose-binding signature GHMP_kinases_C PF08544.8 EGC39234.1 - 3.2e-14 52.8 0.0 7.7e-14 51.6 0.0 1.7 1 0 0 1 1 1 1 GHMP kinases C terminal GHMP_kinases_N PF00288.21 EGC39234.1 - 5.1e-10 39.2 0.1 1e-09 38.3 0.1 1.5 1 0 0 1 1 1 1 GHMP kinases N terminal domain SRP19 PF01922.12 EGC39235.1 - 4.6e-27 94.4 1.4 6.1e-27 94.0 0.4 1.6 2 0 0 2 2 2 1 SRP19 protein zf-DHHC PF01529.15 EGC39237.1 - 7.2e-29 100.3 10.5 7.2e-29 100.3 7.3 2.3 1 1 1 2 2 2 1 DHHC palmitoyltransferase Ank_2 PF12796.2 EGC39237.1 - 5.5e-09 36.2 0.0 1.2e-08 35.2 0.0 1.5 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC39237.1 - 7.2e-08 32.7 0.0 1.7e-07 31.5 0.0 1.6 1 0 0 1 1 1 1 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC39237.1 - 1.2e-07 31.2 0.0 0.0035 17.4 0.0 3.0 2 0 0 2 2 2 2 Ankyrin repeat Ank PF00023.25 EGC39237.1 - 5.3e-07 29.1 0.0 0.00041 20.0 0.0 2.6 2 0 0 2 2 2 2 Ankyrin repeat Ank_5 PF13857.1 EGC39237.1 - 4e-06 26.8 0.0 0.041 14.1 0.0 3.0 1 1 1 2 2 2 2 Ankyrin repeats (many copies) Chorion_3 PF05387.6 EGC39237.1 - 0.14 11.5 1.6 0.23 10.8 1.1 1.2 1 0 0 1 1 1 0 Chorion family 3 CbtA PF09490.5 EGC39237.1 - 0.21 10.8 5.0 3.2 7.0 0.1 2.4 2 0 0 2 2 2 0 Probable cobalt transporter subunit (CbtA) Glycogen_syn PF05693.8 EGC39239.1 - 3.5e-267 887.8 0.0 4.5e-267 887.4 0.0 1.1 1 0 0 1 1 1 1 Glycogen synthase Glycos_transf_1 PF00534.15 EGC39239.1 - 6.3e-06 25.7 0.0 0.00038 19.9 0.0 2.6 2 0 0 2 2 2 1 Glycosyl transferases group 1 Glyco_transf_5 PF08323.6 EGC39239.1 - 0.00027 20.5 0.0 0.00058 19.4 0.0 1.5 1 0 0 1 1 1 1 Starch synthase catalytic domain Glyco_trans_4_4 PF13579.1 EGC39239.1 - 0.022 14.8 0.0 0.042 13.9 0.0 1.4 1 0 0 1 1 1 0 Glycosyl transferase 4-like domain BsuBI_PstI_RE PF06616.6 EGC39239.1 - 0.074 11.8 2.2 0.12 11.1 1.6 1.2 1 0 0 1 1 1 0 BsuBI/PstI restriction endonuclease C-terminus HSP20 PF00011.16 EGC39240.1 - 8.3e-13 48.0 0.0 1.1e-12 47.6 0.0 1.2 1 0 0 1 1 1 1 Hsp20/alpha crystallin family Hus1 PF04005.7 EGC39241.1 - 0.01 14.8 0.4 2 7.2 0.1 2.5 2 0 0 2 2 2 0 Hus1-like protein Endotoxin_N PF03945.9 EGC39242.1 - 8.2e-12 44.9 0.0 1.4e-11 44.2 0.0 1.2 1 0 0 1 1 1 1 delta endotoxin, N-terminal domain VRR_NUC PF08774.6 EGC39242.1 - 0.00075 19.4 0.0 0.0015 18.5 0.0 1.4 1 0 0 1 1 1 1 VRR-NUC domain Pkinase PF00069.20 EGC39243.1 - 3.1e-68 229.7 0.0 3.1e-68 229.7 0.0 4.8 3 1 3 6 6 6 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39243.1 - 1.2e-48 165.4 0.0 1.2e-48 165.4 0.0 2.9 3 0 0 3 3 3 1 Protein tyrosine kinase TPR_2 PF07719.12 EGC39244.1 - 0.00013 21.6 2.9 0.012 15.5 0.0 4.1 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC39244.1 - 0.00045 19.8 4.6 0.0014 18.2 0.0 3.7 3 1 1 4 4 4 1 TPR repeat DNA_repr_REX1B PF14966.1 EGC39246.1 - 0.052 13.9 0.4 0.71 10.2 0.0 2.3 2 0 0 2 2 2 0 DNA repair REX1-B DUF4649 PF15507.1 EGC39247.1 - 0.043 13.5 0.0 0.057 13.1 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4649) Peptidase_M20 PF01546.23 EGC39248.1 - 1.6e-30 106.0 0.0 2.4e-30 105.4 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC39248.1 - 1.5e-18 66.5 0.0 3.3e-18 65.4 0.0 1.5 1 0 0 1 1 1 1 Peptidase dimerisation domain MurB_C PF02873.11 EGC39248.1 - 0.038 13.7 0.2 0.082 12.6 0.1 1.5 1 0 0 1 1 1 0 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain DUF4094 PF13334.1 EGC39249.1 - 0.048 14.0 0.1 0.056 13.8 0.1 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4094) RNA_polI_A14 PF08203.6 EGC39249.1 - 0.064 13.5 1.2 0.084 13.1 0.8 1.2 1 0 0 1 1 1 0 Yeast RNA polymerase I subunit RPA14 DUF2611 PF11022.3 EGC39249.1 - 0.36 10.9 2.0 0.63 10.1 1.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2611) DUF3439 PF11921.3 EGC39251.1 - 3.6 7.3 14.1 12 5.6 9.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Oxysterol_BP PF01237.13 EGC39252.1 - 0.091 11.2 3.3 0.1 11.0 2.3 1.0 1 0 0 1 1 1 0 Oxysterol-binding protein DUF1441 PF07278.6 EGC39252.1 - 3.7 7.1 5.2 14 5.2 3.6 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF1441) Myosin_TH1 PF06017.8 EGC39253.1 - 3.4e-37 127.7 11.3 6.6e-35 120.2 4.5 2.6 2 1 0 2 2 2 2 Myosin tail hSac2 PF12456.3 EGC39253.1 - 0.0049 16.2 0.9 0.013 14.8 0.3 2.0 2 0 0 2 2 2 1 Inositol phosphatase Orthopox_F8 PF05886.6 EGC39254.1 - 4.3 7.2 10.2 0.044 13.6 1.4 1.9 2 0 0 2 2 2 0 Orthopoxvirus F8 protein ABC2_membrane PF01061.19 EGC39255.1 - 1.7e-32 112.3 25.4 2.8e-32 111.6 17.6 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC39255.1 - 2.6e-23 82.8 0.7 6.3e-23 81.5 0.0 1.9 2 0 0 2 2 2 1 ABC transporter AAA_10 PF12846.2 EGC39255.1 - 0.00018 21.0 0.1 0.058 12.8 0.2 2.3 2 0 0 2 2 2 2 AAA-like domain AAA_21 PF13304.1 EGC39255.1 - 0.00086 19.3 15.8 0.00092 19.2 0.8 3.7 3 1 0 3 3 3 1 AAA domain FtsK_SpoIIIE PF01580.13 EGC39255.1 - 0.0081 15.6 0.4 0.014 14.8 0.3 1.3 1 0 0 1 1 1 1 FtsK/SpoIIIE family SMC_N PF02463.14 EGC39255.1 - 0.02 14.1 0.1 9.9 5.3 0.1 3.0 2 1 1 3 3 3 0 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGC39255.1 - 0.023 14.1 0.0 0.15 11.4 0.0 2.0 2 0 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC39255.1 - 0.043 14.6 0.3 0.19 12.5 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA_22 PF13401.1 EGC39255.1 - 0.058 13.5 0.3 0.42 10.7 0.2 2.4 2 1 0 2 2 2 0 AAA domain Miro PF08477.8 EGC39255.1 - 0.058 13.8 0.5 0.52 10.8 0.0 2.6 2 0 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGC39255.1 - 0.092 11.9 0.1 0.17 11.0 0.1 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF258 NACHT PF05729.7 EGC39255.1 - 0.1 12.2 0.4 0.26 10.9 0.0 1.9 2 0 0 2 2 2 0 NACHT domain AAA_29 PF13555.1 EGC39255.1 - 0.16 11.5 2.0 0.2 11.2 0.6 1.8 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_18 PF13238.1 EGC39255.1 - 0.36 11.1 0.0 0.36 11.1 0.0 2.5 2 1 0 2 2 2 0 AAA domain Pro-kuma_activ PF09286.6 EGC39256.1 - 5.8e-34 117.1 0.3 8.9e-34 116.5 0.2 1.3 1 0 0 1 1 1 1 Pro-kumamolisin, activation domain Ribosomal_S17 PF00366.15 EGC39257.1 - 1e-13 51.1 0.3 1.7e-13 50.4 0.2 1.3 1 0 0 1 1 1 1 Ribosomal protein S17 APH PF01636.18 EGC39258.1 - 3.5e-13 49.8 0.0 8.4e-13 48.6 0.0 1.6 2 0 0 2 2 2 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGC39258.1 - 0.024 13.7 0.4 0.024 13.7 0.3 1.7 2 0 0 2 2 2 0 Ecdysteroid kinase VWA_2 PF13519.1 EGC39259.1 - 2.7e-15 56.9 0.0 5.1e-15 55.9 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain ubiquitin PF00240.18 EGC39259.1 - 1e-06 28.0 1.4 1.4e-06 27.5 0.1 1.8 2 0 0 2 2 2 1 Ubiquitin family Miro PF08477.8 EGC39259.1 - 0.089 13.2 5.2 0.11 12.9 0.0 3.5 3 1 1 4 4 4 0 Miro-like protein AAA_16 PF13191.1 EGC39259.1 - 0.19 11.7 0.0 0.7 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA ATPase domain DUF3439 PF11921.3 EGC39259.1 - 3.3 7.4 25.0 0.14 11.8 1.9 2.9 3 0 0 3 3 3 0 Domain of unknown function (DUF3439) DUF4460 PF14687.1 EGC39260.1 - 1.2e-10 41.1 0.9 1.2e-10 41.1 0.6 2.9 2 0 0 2 2 2 1 Domain of unknown function (DUF4460) GLE1 PF07817.8 EGC39260.1 - 0.034 13.0 6.9 0.13 11.2 0.1 3.5 3 0 0 3 3 3 0 GLE1-like protein ubiquitin PF00240.18 EGC39261.1 - 1.2e-13 50.2 0.0 1.8e-13 49.6 0.0 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC39261.1 - 3.9e-08 32.8 0.1 5.9e-08 32.2 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like TUG-UBL1 PF11470.3 EGC39261.1 - 0.0059 16.4 0.3 0.011 15.6 0.0 1.6 2 0 0 2 2 2 1 GLUT4 regulating protein TUG DUF840 PF05801.6 EGC39261.1 - 0.069 13.2 2.9 0.11 12.6 2.0 1.3 1 1 0 1 1 1 0 Lagovirus protein of unknown function (DUF840) Nterm_IS4 PF13006.2 EGC39261.1 - 0.15 12.0 0.0 0.24 11.4 0.0 1.2 1 0 0 1 1 1 0 Insertion element 4 transposase N-terminal Clathrin PF00637.15 EGC39262.1 - 6.5e-199 651.5 60.9 3.5e-33 114.2 0.7 8.8 9 0 0 9 9 9 7 Region in Clathrin and VPS Clathrin_propel PF01394.15 EGC39262.1 - 6.5e-36 120.1 3.6 6.1e-06 26.1 0.0 7.8 7 0 0 7 7 7 7 Clathrin propeller repeat Clathrin_H_link PF13838.1 EGC39262.1 - 6.3e-29 99.6 1.4 2.8e-28 97.5 0.2 2.8 2 0 0 2 2 2 1 Clathrin-H-link Clathrin-link PF09268.5 EGC39262.1 - 4.8e-10 38.2 0.8 4.8e-10 38.2 0.6 2.2 2 0 0 2 2 2 1 Clathrin, heavy-chain linker TPR_1 PF00515.23 EGC39262.1 - 0.0044 16.5 4.4 24 4.7 0.0 5.5 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39262.1 - 0.11 12.4 11.3 22 5.3 0.4 6.5 7 0 0 7 7 7 0 Tetratricopeptide repeat TPR_7 PF13176.1 EGC39262.1 - 0.17 11.7 10.0 5.9 6.9 0.0 6.7 8 0 0 8 8 8 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC39262.1 - 1.6 8.7 11.1 1.1 9.3 0.0 5.3 6 0 0 6 6 6 0 Tetratricopeptide repeat PixA PF12306.3 EGC39263.1 - 0.087 12.6 1.4 0.096 12.5 1.0 1.1 1 0 0 1 1 1 0 Inclusion body protein Pex14_N PF04695.8 EGC39263.1 - 2.9 7.9 7.5 3.2 7.8 5.2 1.0 1 0 0 1 1 1 0 Peroxisomal membrane anchor protein (Pex14p) conserved region MIF4G PF02854.14 EGC39264.1 - 2.6e-38 131.5 15.5 6e-38 130.3 10.7 1.7 1 0 0 1 1 1 1 MIF4G domain MA3 PF02847.12 EGC39264.1 - 4.3e-06 26.4 1.1 9.3e-05 22.1 0.0 2.5 2 0 0 2 2 2 1 MA3 domain UCH PF00443.24 EGC39265.1 - 2.1e-48 164.7 1.4 3e-48 164.2 1.0 1.2 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC39265.1 - 1.7e-18 67.0 10.2 9e-18 64.7 1.4 2.4 2 1 0 2 2 2 2 Ubiquitin carboxyl-terminal hydrolase PRMT5 PF05185.11 EGC39266.1 - 1.5e-13 50.5 0.1 1.8e-13 50.2 0.1 1.1 1 0 0 1 1 1 1 PRMT5 arginine-N-methyltransferase PrmA PF06325.8 EGC39266.1 - 4.1e-09 35.9 0.0 6.6e-09 35.3 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_31 PF13847.1 EGC39266.1 - 5.4e-08 32.5 0.3 2.8e-07 30.2 0.0 2.1 1 1 1 2 2 2 1 Methyltransferase domain MTS PF05175.9 EGC39266.1 - 6.2e-08 32.1 0.1 1e-07 31.4 0.1 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_26 PF13659.1 EGC39266.1 - 3.4e-07 30.3 0.0 6e-07 29.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39266.1 - 8.8e-06 26.2 0.0 2.2e-05 24.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39266.1 - 0.00019 21.8 0.0 0.00052 20.4 0.0 1.8 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC39266.1 - 0.00024 21.4 0.0 0.00043 20.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGC39266.1 - 0.00028 20.5 0.1 0.00046 19.8 0.0 1.3 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_23 PF13489.1 EGC39266.1 - 0.00053 19.7 0.0 0.0012 18.5 0.0 1.6 1 1 1 2 2 2 1 Methyltransferase domain Methyltransf_16 PF10294.4 EGC39266.1 - 0.0032 16.9 0.0 0.0052 16.2 0.0 1.3 1 0 0 1 1 1 1 Putative methyltransferase FtsJ PF01728.14 EGC39266.1 - 0.03 14.3 0.0 0.054 13.4 0.0 1.3 1 0 0 1 1 1 0 FtsJ-like methyltransferase Cons_hypoth95 PF03602.10 EGC39266.1 - 0.041 13.2 0.1 0.071 12.4 0.1 1.3 1 0 0 1 1 1 0 Conserved hypothetical protein 95 Methyltransf_21 PF05050.7 EGC39266.1 - 0.089 12.7 0.0 0.3 11.0 0.0 1.9 1 1 0 1 1 1 0 Methyltransferase FkbM domain PC4 PF02229.11 EGC39267.1 - 5.6e-17 60.7 0.1 5.6e-17 60.7 0.1 2.0 3 0 0 3 3 3 1 Transcriptional Coactivator p15 (PC4) DUF2457 PF10446.4 EGC39267.1 - 0.065 11.9 11.0 0.083 11.6 7.7 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Dsh_C PF12316.3 EGC39267.1 - 0.14 12.2 6.3 0.18 11.9 4.4 1.2 1 0 0 1 1 1 0 Segment polarity protein dishevelled (Dsh) C terminal LAT PF15234.1 EGC39267.1 - 0.16 11.4 3.7 0.19 11.1 2.5 1.1 1 0 0 1 1 1 0 Linker for activation of T-cells FAM176 PF14851.1 EGC39267.1 - 0.26 10.9 7.0 0.39 10.4 4.8 1.3 1 0 0 1 1 1 0 FAM176 family Peptidase_S64 PF08192.6 EGC39267.1 - 0.31 9.3 9.5 0.32 9.2 6.6 1.0 1 0 0 1 1 1 0 Peptidase family S64 PRP21_like_P PF12230.3 EGC39267.1 - 0.34 10.4 9.7 0.43 10.0 6.7 1.3 1 0 0 1 1 1 0 Pre-mRNA splicing factor PRP21 like protein TFIIF_alpha PF05793.7 EGC39267.1 - 0.37 9.1 20.5 0.41 8.9 14.2 1.1 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) SAPS PF04499.10 EGC39267.1 - 0.38 9.3 8.2 0.38 9.3 5.7 1.1 1 0 0 1 1 1 0 SIT4 phosphatase-associated protein CobT PF06213.7 EGC39267.1 - 0.45 9.5 17.0 0.59 9.2 11.8 1.2 1 0 0 1 1 1 0 Cobalamin biosynthesis protein CobT SR-25 PF10500.4 EGC39267.1 - 0.49 9.8 19.4 0.7 9.3 13.4 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein TRAP_alpha PF03896.11 EGC39267.1 - 0.6 9.0 5.8 0.67 8.8 4.0 1.2 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF4638 PF15472.1 EGC39267.1 - 1.1 8.8 9.0 1.2 8.6 6.3 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4638) CDC45 PF02724.9 EGC39267.1 - 1.4 6.8 12.9 1.6 6.6 8.9 1.0 1 0 0 1 1 1 0 CDC45-like protein SpoIIIAH PF12685.2 EGC39267.1 - 1.9 7.9 12.6 2.2 7.7 8.7 1.1 1 0 0 1 1 1 0 SpoIIIAH-like protein DUF4637 PF15470.1 EGC39267.1 - 2.1 7.9 8.6 2.7 7.5 6.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) PI3K_1B_p101 PF10486.4 EGC39267.1 - 2.1 5.7 6.9 2.2 5.7 4.8 1.0 1 0 0 1 1 1 0 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Pox_RNA_Pol_19 PF05320.7 EGC39267.1 - 2.6 7.7 10.3 4.2 7.0 7.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit Vfa1 PF08432.5 EGC39267.1 - 3.6 7.5 16.4 4.3 7.3 11.3 1.2 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 SSP160 PF06933.6 EGC39267.1 - 4.1 5.2 10.5 5.1 4.9 7.3 1.1 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 FAM60A PF15396.1 EGC39267.1 - 4.2 7.0 10.8 5 6.8 7.5 1.1 1 0 0 1 1 1 0 Protein Family FAM60A eIF-3c_N PF05470.7 EGC39267.1 - 4.4 5.2 11.9 5 5.0 8.3 1.1 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus Macoilin PF09726.4 EGC39267.1 - 4.7 5.3 14.2 5.3 5.2 9.8 1.0 1 0 0 1 1 1 0 Transmembrane protein DUF1510 PF07423.6 EGC39267.1 - 4.9 6.4 18.2 6.6 6.0 12.6 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Mem_trans PF03547.13 EGC39267.1 - 7.9 4.6 7.4 9.2 4.4 5.2 1.1 1 0 0 1 1 1 0 Membrane transport protein APC_CDC26 PF10471.4 EGC39267.1 - 8 7.2 12.5 3.5 8.4 6.7 1.8 2 0 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Hid1 PF12722.2 EGC39267.1 - 8.7 3.8 11.8 9.2 3.7 8.2 1.0 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein Nucleoplasmin PF03066.10 EGC39267.1 - 9 5.8 11.3 16 5.0 7.9 1.3 1 0 0 1 1 1 0 Nucleoplasmin PH PF00169.24 EGC39268.1 - 2.7e-14 53.2 1.9 6.8e-14 51.9 1.3 1.7 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC39268.1 - 2.6e-05 24.4 5.7 0.00066 19.9 3.9 2.5 1 1 0 1 1 1 1 Pleckstrin homology domain DnaJ-X PF14308.1 EGC39268.1 - 0.31 10.2 5.6 0.48 9.6 3.9 1.2 1 0 0 1 1 1 0 X-domain of DnaJ-containing VPS9 PF02204.13 EGC39269.1 - 3.8e-11 42.9 0.1 3.5e-10 39.8 0.0 2.6 1 1 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain Polyketide_cyc2 PF10604.4 EGC39270.1 - 3.1e-06 27.4 0.0 5.2e-06 26.6 0.0 1.4 1 1 0 1 1 1 1 Polyketide cyclase / dehydrase and lipid transport TPD PF14811.1 EGC39271.1 - 1.5e-47 160.5 0.1 4.5e-47 159.0 0.1 1.7 2 0 0 2 2 2 1 Protein of unknown function TPD sequence-motif TPT PF03151.11 EGC39272.1 - 2.6e-20 72.6 13.5 2.6e-20 72.6 9.3 2.2 2 0 0 2 2 2 2 Triose-phosphate Transporter family UAA PF08449.6 EGC39272.1 - 3.4e-15 55.7 32.9 5.7e-15 55.0 22.8 1.2 1 0 0 1 1 1 1 UAA transporter family EamA PF00892.15 EGC39272.1 - 4.3e-08 33.2 36.0 8e-05 22.6 9.7 2.6 2 1 0 2 2 2 2 EamA-like transporter family DUF2648 PF10855.3 EGC39272.1 - 0.023 14.1 0.0 0.061 12.7 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2648) Tnp_P_element_C PF12596.3 EGC39272.1 - 0.11 12.8 0.4 0.24 11.7 0.3 1.5 1 0 0 1 1 1 0 87kDa Transposase ABC2_membrane PF01061.19 EGC39273.1 - 2.8e-35 121.3 26.7 4.7e-35 120.6 18.5 1.4 1 0 0 1 1 1 1 ABC-2 type transporter ABC_tran PF00005.22 EGC39273.1 - 7.6e-30 103.9 0.3 1.7e-29 102.8 0.2 1.6 1 0 0 1 1 1 1 ABC transporter ABC2_membrane_3 PF12698.2 EGC39273.1 - 8.6e-08 31.5 27.6 8.6e-08 31.5 19.1 2.6 2 1 1 3 3 3 1 ABC-2 family transporter protein AAA_21 PF13304.1 EGC39273.1 - 3.7e-06 27.1 16.3 0.0046 16.9 0.0 4.2 3 1 0 4 4 4 2 AAA domain AAA_29 PF13555.1 EGC39273.1 - 2.4e-05 23.7 0.1 5.2e-05 22.6 0.1 1.5 1 0 0 1 1 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC39273.1 - 6.4e-05 22.2 0.4 0.00011 21.4 0.2 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SMC_N PF02463.14 EGC39273.1 - 6.5e-05 22.2 0.2 0.00052 19.3 0.1 2.2 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_25 PF13481.1 EGC39273.1 - 0.00066 19.1 0.0 0.0013 18.1 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC39273.1 - 0.0013 19.0 1.1 0.0029 17.9 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_17 PF13207.1 EGC39273.1 - 0.003 18.3 0.0 0.0072 17.1 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC39273.1 - 0.0037 17.4 0.0 0.0087 16.2 0.0 1.6 1 0 0 1 1 1 1 AAA domain DUF3149 PF11346.3 EGC39273.1 - 0.008 15.7 0.9 0.068 12.7 0.1 2.8 2 0 0 2 2 2 1 Protein of unknown function (DUF3149) AAA_16 PF13191.1 EGC39273.1 - 0.0089 16.0 0.0 0.014 15.3 0.0 1.3 1 0 0 1 1 1 1 AAA ATPase domain Miro PF08477.8 EGC39273.1 - 0.02 15.3 0.1 0.052 14.0 0.1 1.7 1 0 0 1 1 1 0 Miro-like protein MMR_HSR1 PF01926.18 EGC39273.1 - 0.035 14.0 0.0 0.086 12.8 0.0 1.7 1 0 0 1 1 1 0 50S ribosome-binding GTPase SbcCD_C PF13558.1 EGC39273.1 - 0.04 13.8 0.1 0.28 11.1 0.1 2.3 1 1 0 1 1 1 0 Putative exonuclease SbcCD, C subunit NACHT PF05729.7 EGC39273.1 - 0.081 12.5 0.4 0.16 11.6 0.3 1.5 1 0 0 1 1 1 0 NACHT domain AAA_10 PF12846.2 EGC39273.1 - 0.097 12.0 0.1 0.18 11.2 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain AAA_33 PF13671.1 EGC39273.1 - 0.12 12.2 0.0 0.2 11.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC39273.1 - 0.18 11.3 0.0 0.27 10.8 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_23 PF13476.1 EGC39273.1 - 1.3 9.2 12.9 1.3 9.3 0.3 2.6 1 1 1 2 2 2 0 AAA domain OppC_N PF12911.2 EGC39273.1 - 3 7.2 9.2 0.036 13.4 0.6 2.1 2 0 0 2 2 1 0 N-terminal TM domain of oligopeptide transport permease C PDR_CDR PF06422.7 EGC39273.1 - 4.4 7.0 7.8 0.43 10.2 0.4 2.6 2 0 0 2 2 2 0 CDR ABC transporter Rhodanese PF00581.15 EGC39274.1 - 7.1e-11 42.4 0.3 1.2e-08 35.3 0.2 2.3 1 1 0 1 1 1 1 Rhodanese-like domain PPR_2 PF13041.1 EGC39275.1 - 1.3e-17 63.4 6.0 3.3e-10 39.7 0.0 5.0 3 1 2 5 5 5 3 PPR repeat family PPR PF01535.15 EGC39275.1 - 7.6e-11 41.2 0.1 0.24 11.4 0.0 4.6 4 0 0 4 4 4 4 PPR repeat PPR_3 PF13812.1 EGC39275.1 - 1.3e-08 34.4 0.4 0.23 11.8 0.0 4.9 5 0 0 5 5 5 2 Pentatricopeptide repeat domain PPR_1 PF12854.2 EGC39275.1 - 0.0003 20.2 0.0 3.9 7.0 0.0 3.6 3 0 0 3 3 3 2 PPR repeat zf-RING_2 PF13639.1 EGC39277.1 - 6.6e-10 38.6 10.8 1.4e-09 37.5 7.5 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39277.1 - 5.8e-07 29.0 7.8 1.1e-06 28.2 5.4 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39277.1 - 1.1e-06 28.6 6.0 2.9e-06 27.2 4.1 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC39277.1 - 5e-06 26.0 13.7 1.4e-05 24.6 9.5 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39277.1 - 1.4e-05 25.0 13.3 3.6e-05 23.6 9.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39277.1 - 0.002 17.7 12.4 0.0051 16.5 8.6 1.7 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC39277.1 - 0.03 14.1 5.4 0.083 12.7 3.7 1.7 1 1 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC39277.1 - 0.13 12.1 13.0 0.33 10.8 9.0 1.8 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC39277.1 - 0.79 9.5 4.6 1.7 8.4 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein 2_5_RNA_ligase2 PF13563.1 EGC39278.1 - 0.0001 22.0 0.0 0.00011 21.9 0.0 1.0 1 0 0 1 1 1 1 2'-5' RNA ligase superfamily COMP PF11598.3 EGC39278.1 - 0.056 13.5 0.0 0.27 11.3 0.0 1.8 2 0 0 2 2 2 0 Cartilage oligomeric matrix protein F5_F8_type_C PF00754.20 EGC39279.1 - 2.9e-23 82.1 2.7 4.8e-23 81.3 1.9 1.4 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC39279.1 - 5.2e-21 74.0 0.1 1.2e-20 72.9 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain HSP33 PF01430.14 EGC39280.1 - 8.3e-41 139.9 0.4 3.1e-40 138.0 0.3 1.9 1 1 0 1 1 1 1 Hsp33 protein PLDc PF00614.17 EGC39280.1 - 1.6e-05 24.5 1.3 0.012 15.4 0.1 2.9 2 0 0 2 2 2 2 Phospholipase D Active site motif TIG PF01833.19 EGC39281.1 - 3.4e-13 49.3 66.7 1.6e-05 24.8 1.5 7.7 7 0 0 7 7 7 5 IPT/TIG domain EGF_2 PF07974.8 EGC39281.1 - 0.0016 18.5 5.9 0.0016 18.5 4.1 2.9 2 0 0 2 2 2 1 EGF-like domain EB PF01683.13 EGC39281.1 - 0.56 10.3 16.3 2.5 8.2 2.2 2.7 2 0 0 2 2 2 0 EB module Histone PF00125.19 EGC39282.1 - 2e-12 47.0 0.2 2.5e-12 46.7 0.1 1.1 1 0 0 1 1 1 1 Core histone H2A/H2B/H3/H4 CENP-S PF15630.1 EGC39282.1 - 8.1e-05 22.7 0.0 0.00023 21.2 0.0 1.7 2 0 0 2 2 2 1 Kinetochore component CENP-S TAF PF02969.12 EGC39282.1 - 0.00052 19.9 0.0 0.00068 19.5 0.0 1.3 1 0 0 1 1 1 1 TATA box binding protein associated factor (TAF) Ribosomal_L29e PF01779.12 EGC39282.1 - 0.0019 18.0 2.2 0.054 13.3 2.5 2.0 1 1 1 2 2 2 1 Ribosomal L29e protein family CBFD_NFYB_HMF PF00808.18 EGC39282.1 - 0.004 17.1 0.0 0.0093 16.0 0.0 1.6 1 1 0 1 1 1 1 Histone-like transcription factor (CBF/NF-Y) and archaeal histone Bromo_TP PF07524.8 EGC39282.1 - 0.0041 16.8 0.1 0.0063 16.2 0.0 1.4 1 1 0 1 1 1 1 Bromodomain associated TFIID-18kDa PF02269.11 EGC39282.1 - 0.028 14.2 0.0 0.037 13.8 0.0 1.4 1 0 0 1 1 1 0 Transcription initiation factor IID, 18kD subunit TFIID-31kDa PF02291.10 EGC39282.1 - 0.057 13.2 0.0 0.057 13.2 0.0 1.2 1 0 0 1 1 1 0 Transcription initiation factor IID, 31kD subunit CENP-T PF15511.1 EGC39282.1 - 0.12 11.6 0.0 0.12 11.5 0.0 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T CRT-like PF08627.5 EGC39283.1 - 5.8e-45 152.3 4.7 5.8e-45 152.3 3.2 2.3 3 0 0 3 3 3 1 CRT-like DUF914 PF06027.7 EGC39283.1 - 2e-07 30.1 11.9 6.4e-07 28.5 2.4 2.1 2 0 0 2 2 2 2 Eukaryotic protein of unknown function (DUF914) TPT PF03151.11 EGC39283.1 - 5.6e-05 22.8 2.1 5.6e-05 22.8 1.4 3.3 3 1 0 3 3 3 1 Triose-phosphate Transporter family EamA PF00892.15 EGC39283.1 - 0.003 17.6 27.4 0.035 14.1 7.3 3.2 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGC39283.1 - 0.0041 17.2 15.2 0.1 12.7 2.3 2.6 2 0 0 2 2 2 2 Multidrug resistance efflux transporter Lipase_GDSL_2 PF13472.1 EGC39284.1 - 4.9e-06 26.7 0.0 7e-06 26.2 0.0 1.3 1 0 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase family Lipase_GDSL PF00657.17 EGC39284.1 - 0.0037 17.1 0.5 0.075 12.8 0.3 2.4 1 1 0 1 1 1 1 GDSL-like Lipase/Acylhydrolase DAGK_acc PF00609.14 EGC39285.1 - 5.4e-50 169.6 0.3 3.5e-48 163.8 0.2 2.6 1 1 0 1 1 1 1 Diacylglycerol kinase accessory domain DAGK_cat PF00781.19 EGC39285.1 - 4.3e-29 100.5 0.0 7.6e-29 99.7 0.0 1.4 1 0 0 1 1 1 1 Diacylglycerol kinase catalytic domain C1_1 PF00130.17 EGC39285.1 - 5e-27 93.3 50.4 3.4e-10 39.4 9.0 3.3 3 0 0 3 3 3 3 Phorbol esters/diacylglycerol binding domain (C1 domain) Mito_carr PF00153.22 EGC39286.1 - 2e-17 62.6 0.5 1e-07 31.5 0.0 3.7 3 1 0 3 3 3 3 Mitochondrial carrier protein Chordopox_A33R PF05966.7 EGC39286.1 - 0.025 13.3 0.2 0.043 12.5 0.1 1.3 1 0 0 1 1 1 0 Chordopoxvirus A33R protein Tetraspannin PF00335.15 EGC39287.1 - 0.00045 19.5 1.0 0.00045 19.5 0.7 1.4 2 0 0 2 2 2 1 Tetraspanin family DUF2207 PF09972.4 EGC39287.1 - 0.086 11.4 0.1 0.1 11.1 0.1 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) FNIP PF05725.7 EGC39288.1 - 2.5e-102 334.6 86.7 7.7e-18 64.1 0.7 11.4 7 2 6 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC39288.1 - 1.5e-07 31.2 27.1 0.38 10.7 0.0 10.0 4 2 7 11 11 11 7 Protein of unknown function (DUF1769) Pkinase PF00069.20 EGC39289.1 - 3.2e-26 92.0 0.1 8.3e-23 80.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39289.1 - 5.6e-16 58.4 0.1 5.1e-13 48.6 0.0 2.0 1 1 1 2 2 2 2 Protein tyrosine kinase Kinase-like PF14531.1 EGC39289.1 - 1.1e-06 27.8 0.0 1.4e-06 27.5 0.0 1.1 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC39289.1 - 0.014 15.1 0.0 0.018 14.8 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC39289.1 - 0.035 13.6 0.2 0.085 12.4 0.1 1.6 2 0 0 2 2 2 0 Choline/ethanolamine kinase UBN2_2 PF14227.1 EGC39289.1 - 0.082 12.4 0.5 0.14 11.7 0.1 1.6 2 0 0 2 2 2 0 gag-polypeptide of LTR copia-type Methyltransf_12 PF08242.7 EGC39290.1 - 4.3e-10 39.9 0.0 7.4e-10 39.2 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_PK PF05891.7 EGC39290.1 - 1.7e-09 37.2 0.0 2e-09 37.0 0.0 1.1 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase Methyltransf_23 PF13489.1 EGC39290.1 - 6.4e-09 35.7 0.2 1.1e-08 34.9 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39290.1 - 7e-08 33.0 0.0 1.2e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39290.1 - 1.1e-06 29.0 0.0 1.6e-06 28.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC39290.1 - 1.7e-06 27.6 0.0 2.5e-06 27.1 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC39290.1 - 0.00012 22.0 0.0 0.0002 21.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC39290.1 - 0.0013 19.0 0.0 0.0021 18.4 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain DREV PF05219.7 EGC39290.1 - 0.0019 17.1 0.1 0.0029 16.5 0.1 1.2 1 0 0 1 1 1 1 DREV methyltransferase RrnaAD PF00398.15 EGC39290.1 - 0.0022 17.0 0.0 0.0027 16.7 0.0 1.1 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase MTS PF05175.9 EGC39290.1 - 0.022 14.1 0.0 0.032 13.5 0.0 1.2 1 0 0 1 1 1 0 Methyltransferase small domain DUF938 PF06080.7 EGC39290.1 - 0.07 12.6 0.0 0.23 10.9 0.0 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF938) ELO PF01151.13 EGC39291.1 - 2.8e-51 174.2 27.3 3.3e-51 174.0 18.9 1.0 1 0 0 1 1 1 1 GNS1/SUR4 family SEEK1 PF15357.1 EGC39292.1 - 0.017 14.9 3.7 0.035 14.0 2.6 1.4 1 0 0 1 1 1 0 Psoriasis susceptibility 1 candidate 1 DUF3329 PF11808.3 EGC39292.1 - 0.25 11.4 0.0 0.56 10.3 0.0 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3329) zf-C4H2 PF10146.4 EGC39293.1 - 3.9e-07 30.3 25.0 3.9e-07 30.3 17.3 2.1 2 1 0 2 2 2 1 Zinc finger-containing protein MRP-S33 PF08293.6 EGC39293.1 - 0.28 11.1 4.7 0.24 11.3 0.2 2.8 1 1 2 3 3 3 0 Mitochondrial ribosomal subunit S27 Cob_adeno_trans PF01923.13 EGC39293.1 - 0.38 10.5 4.4 0.2 11.4 0.4 2.1 1 1 1 2 2 2 0 Cobalamin adenosyltransferase TFIIB PF00382.14 EGC39294.1 - 0.002 17.8 0.0 0.0054 16.5 0.0 1.7 1 0 0 1 1 1 1 Transcription factor TFIIB repeat A2L_zn_ribbon PF08792.5 EGC39294.1 - 0.039 13.4 4.0 0.11 11.9 2.7 1.8 1 0 0 1 1 1 0 A2L zinc ribbon domain Prok-RING_1 PF14446.1 EGC39294.1 - 5.3 6.8 8.3 1.3 8.7 2.7 2.2 2 0 0 2 2 2 0 Prokaryotic RING finger family 1 Uso1_p115_head PF04869.9 EGC39295.1 - 2.3e-36 125.1 3.4 2.3e-36 125.1 2.4 2.6 2 0 0 2 2 2 1 Uso1 / p115 like vesicle tethering protein, head region SKG6 PF08693.5 EGC39296.1 - 1.8e-05 23.9 0.1 3.8e-05 22.9 0.1 1.6 1 0 0 1 1 1 1 Transmembrane alpha-helix domain DUF485 PF04341.7 EGC39296.1 - 0.036 13.7 0.8 0.11 12.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function, DUF485 Dicty_spore_N PF04562.7 EGC39297.1 - 3.8e-20 72.3 26.0 3.8e-20 72.3 18.0 5.1 4 1 0 5 5 5 3 Dictyostelium spore coat protein, N terminus TILa PF12714.2 EGC39297.1 - 1.8 8.3 45.2 0.21 11.3 1.2 7.2 5 1 1 6 6 6 0 TILa domain Metallophos PF00149.23 EGC39298.1 - 9.4e-41 139.4 0.3 9.4e-41 139.4 0.2 1.8 2 0 0 2 2 2 1 Calcineurin-like phosphoesterase WD40 PF00400.27 EGC39299.1 - 6.1e-09 35.4 14.1 0.00028 20.6 0.1 7.2 7 0 0 7 7 7 4 WD domain, G-beta repeat ubiquitin PF00240.18 EGC39300.1 - 2e-34 116.8 1.3 2.6e-34 116.4 0.6 1.5 2 0 0 2 2 2 1 Ubiquitin family Ribosomal_S27 PF01599.14 EGC39300.1 - 1.2e-27 95.3 3.2 2.3e-27 94.5 2.2 1.5 1 0 0 1 1 1 1 Ribosomal protein S27a Rad60-SLD PF11976.3 EGC39300.1 - 1.5e-19 69.4 0.7 2.5e-19 68.7 0.5 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC39300.1 - 1.9e-05 24.7 0.1 8.5e-05 22.7 0.1 1.9 1 1 0 1 1 1 1 Ubiquitin-like domain Telomere_Sde2 PF13019.1 EGC39300.1 - 0.0015 18.2 0.0 0.0024 17.5 0.0 1.3 1 0 0 1 1 1 1 Telomere stability and silencing Rad60-SLD_2 PF13881.1 EGC39300.1 - 0.0048 16.7 0.2 0.01 15.7 0.1 1.7 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like IBR PF01485.16 EGC39300.1 - 0.0075 16.1 0.5 0.012 15.5 0.3 1.3 1 0 0 1 1 1 1 IBR domain DUF2407 PF10302.4 EGC39300.1 - 0.013 15.6 0.3 0.017 15.2 0.2 1.3 1 1 0 1 1 1 0 DUF2407 ubiquitin-like domain zf-CGNR PF11706.3 EGC39300.1 - 0.067 12.7 0.6 0.12 11.8 0.4 1.4 1 0 0 1 1 1 0 CGNR zinc finger DUF2870 PF11069.3 EGC39300.1 - 0.094 12.7 0.1 0.25 11.4 0.0 1.9 1 1 0 1 1 1 0 Protein of unknown function (DUF2870) Plexin_cytopl PF08337.7 EGC39300.1 - 0.12 10.7 0.4 4.6 5.4 0.0 2.1 1 1 1 2 2 2 0 Plexin cytoplasmic RasGAP domain BTB_2 PF02214.17 EGC39301.1 - 5.9e-22 77.6 0.0 1.2e-21 76.6 0.0 1.5 1 0 0 1 1 1 1 BTB/POZ domain TPR_19 PF14559.1 EGC39301.1 - 1.7e-05 25.0 0.0 3.3e-05 24.1 0.0 1.4 1 0 0 1 1 1 1 Tetratricopeptide repeat Fis1_TPR_N PF14852.1 EGC39301.1 - 4.8e-05 22.5 0.1 0.00025 20.2 0.0 2.1 2 0 0 2 2 2 1 Fis1 N-terminal tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC39301.1 - 0.001 18.8 0.1 0.0026 17.5 0.1 1.6 1 0 0 1 1 1 1 Fis1 C-terminal tetratricopeptide repeat TPR_14 PF13428.1 EGC39301.1 - 0.038 14.6 0.0 0.39 11.4 0.0 2.3 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_16 PF13432.1 EGC39301.1 - 0.058 14.0 0.0 0.11 13.1 0.0 1.4 1 0 0 1 1 1 0 Tetratricopeptide repeat Apc3 PF12895.2 EGC39301.1 - 0.095 12.8 0.2 0.2 11.7 0.2 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex, cyclosome, subunit 3 CH PF00307.26 EGC39302.1 - 4.5e-38 129.6 0.4 1.4e-17 63.6 0.0 2.8 3 0 0 3 3 3 2 Calponin homology (CH) domain Cortex-I_coil PF09304.5 EGC39302.1 - 1.1e-36 125.1 24.1 1.1e-36 125.1 16.7 3.1 2 1 1 3 3 3 1 Cortexillin I, coiled coil CAMSAP_CH PF11971.3 EGC39302.1 - 3.2e-07 29.8 0.0 6.1e-05 22.5 0.0 2.8 2 1 0 2 2 2 1 CAMSAP CH domain DUF1217 PF06748.7 EGC39302.1 - 0.0066 16.5 2.0 0.031 14.3 1.1 2.3 1 1 0 1 1 1 1 Protein of unknown function (DUF1217) Reo_sigmaC PF04582.7 EGC39302.1 - 0.46 9.6 2.5 0.35 10.0 0.7 1.5 2 0 0 2 2 2 0 Reovirus sigma C capsid protein CENP-F_leu_zip PF10473.4 EGC39302.1 - 5.3 6.9 39.9 7 6.5 4.8 3.9 2 1 1 3 3 3 0 Leucine-rich repeats of kinetochore protein Cenp-F/LEK1 Baculo_PEP_C PF04513.7 EGC39302.1 - 7.3 6.4 10.4 1 9.1 1.6 2.2 2 1 1 3 3 3 0 Baculovirus polyhedron envelope protein, PEP, C terminus SapB_1 PF05184.10 EGC39303.1 - 4.1e-18 64.7 12.7 2.2e-10 40.1 0.3 3.5 3 1 0 3 3 3 2 Saposin-like type B, region 1 SapB_2 PF03489.12 EGC39303.1 - 4.3e-13 49.0 3.4 3.2e-08 33.4 0.2 2.8 2 0 0 2 2 2 2 Saposin-like type B, region 2 DUF3456 PF11938.3 EGC39303.1 - 0.046 13.7 2.9 3.9 7.4 0.0 3.2 2 1 1 3 3 3 0 TLR4 regulator and MIR-interacting MSAP UPF0547 PF10571.4 EGC39303.1 - 0.11 12.2 0.8 0.38 10.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised protein family UPF0547 C1_3 PF07649.7 EGC39303.1 - 0.28 11.2 2.8 1.3 9.1 0.2 2.6 2 0 0 2 2 2 0 C1-like domain Calici_PP_N PF08405.6 EGC39304.1 - 0.0023 16.8 0.0 0.11 11.3 0.0 2.1 2 0 0 2 2 2 2 Viral polyprotein N-terminal PARP PF00644.15 EGC39305.1 - 0.00015 21.2 3.5 0.035 13.5 1.7 3.8 2 1 0 2 2 2 2 Poly(ADP-ribose) polymerase catalytic domain Rho_GDI PF02115.12 EGC39306.1 - 7.8e-21 74.4 0.3 8.5e-21 74.2 0.2 1.0 1 0 0 1 1 1 1 RHO protein GDP dissociation inhibitor DUF4402 PF14352.1 EGC39306.1 - 0.098 13.1 0.0 0.14 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4402) DUF4598 PF15370.1 EGC39307.1 - 4.9e-13 49.3 12.2 1.8e-12 47.5 8.5 2.0 1 1 0 1 1 1 1 Domain of unknown function (DUF4598) DUF2172 PF09940.4 EGC39307.1 - 0.2 9.9 3.4 0.27 9.5 2.4 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF2172) Ras PF00071.17 EGC39308.1 - 1.4e-61 206.5 1.2 1.7e-61 206.3 0.8 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39308.1 - 1.8e-19 70.3 0.1 2.9e-19 69.7 0.1 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39308.1 - 2.5e-14 52.9 0.2 3.2e-14 52.5 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC39308.1 - 1.2e-07 31.6 0.1 2e-07 30.9 0.0 1.5 1 1 0 1 1 1 1 50S ribosome-binding GTPase SRPRB PF09439.5 EGC39308.1 - 8e-06 25.1 0.2 1.3e-05 24.4 0.2 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Arch_ATPase PF01637.13 EGC39308.1 - 4.9e-05 23.1 1.0 0.067 12.8 0.0 2.1 1 1 1 2 2 2 2 Archaeal ATPase AAA_22 PF13401.1 EGC39308.1 - 0.0056 16.8 0.0 0.093 12.8 0.0 2.3 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC39308.1 - 0.0056 16.5 0.4 0.16 11.8 0.1 2.6 1 1 1 2 2 2 1 AAA domain DUF258 PF03193.11 EGC39308.1 - 0.011 14.8 0.0 0.024 13.8 0.0 1.7 1 1 0 1 1 1 0 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGC39308.1 - 0.013 14.6 0.4 0.02 14.0 0.3 1.3 1 0 0 1 1 1 0 Gtr1/RagA G protein conserved region FeoB_N PF02421.13 EGC39308.1 - 0.025 13.8 1.0 0.22 10.8 0.7 2.1 1 1 0 1 1 1 0 Ferrous iron transport protein B AAA_18 PF13238.1 EGC39308.1 - 0.027 14.7 0.1 0.19 12.0 0.1 2.1 1 1 0 1 1 1 0 AAA domain Septin PF00735.13 EGC39308.1 - 0.051 12.5 0.6 0.078 11.9 0.0 1.5 2 0 0 2 2 2 0 Septin AAA_16 PF13191.1 EGC39308.1 - 0.086 12.8 0.0 0.61 10.0 0.0 2.0 1 1 0 1 1 1 0 AAA ATPase domain FNIP PF05725.7 EGC39309.1 - 3.5e-25 87.6 36.1 6.2e-07 29.2 1.2 9.0 5 3 3 9 9 9 8 FNIP Repeat LRR_4 PF12799.2 EGC39309.1 - 0.016 14.8 7.3 0.3 10.7 1.8 4.1 4 0 0 4 4 4 0 Leucine Rich repeats (2 copies) SET PF00856.23 EGC39312.1 - 1.1e-11 45.2 1.1 7.4e-09 36.1 0.2 2.7 3 0 0 3 3 3 2 SET domain zf-MYND PF01753.13 EGC39312.1 - 7.4e-11 41.7 9.6 7.4e-11 41.7 6.6 3.1 3 0 0 3 3 3 1 MYND finger IF-2B PF01008.12 EGC39312.1 - 0.089 11.7 0.0 0.16 10.9 0.0 1.4 1 0 0 1 1 1 0 Initiation factor 2 subunit family GCM PF03615.10 EGC39312.1 - 3 7.4 9.8 1.1 8.8 0.6 2.5 2 1 0 2 2 2 0 GCM motif protein CLU PF13236.1 EGC39313.1 - 4.6e-41 140.6 2.1 5.8e-41 140.3 0.0 2.4 2 0 0 2 2 2 1 Clustered mitochondria UPF0278 PF08745.6 EGC39314.1 - 0.047 12.9 0.0 11 5.2 0.0 2.8 2 1 1 3 3 3 0 UPF0278 family eIF_4EBP PF05456.6 EGC39314.1 - 0.45 10.2 3.4 5.3 6.7 0.0 2.4 2 0 0 2 2 2 0 Eukaryotic translation initiation factor 4E binding protein (EIF4EBP) Secretin_N_2 PF07655.8 EGC39314.1 - 1.1 9.6 12.0 3.4 8.1 8.3 1.8 1 0 0 1 1 1 0 Secretin N-terminal domain TPR_11 PF13414.1 EGC39315.1 - 7e-07 28.8 0.4 0.00056 19.5 0.0 1.9 1 1 1 2 2 2 2 TPR repeat TPR_17 PF13431.1 EGC39315.1 - 0.0027 17.7 0.0 0.035 14.2 0.0 2.0 1 1 1 2 2 2 1 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39315.1 - 0.011 15.5 0.3 0.65 10.0 0.0 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat zf-RNPHF PF08080.7 EGC39315.1 - 0.014 14.8 0.1 0.021 14.3 0.1 1.2 1 0 0 1 1 1 0 RNPHF zinc finger TPR_1 PF00515.23 EGC39315.1 - 0.03 13.9 0.2 0.32 10.6 0.1 2.5 3 0 0 3 3 3 0 Tetratricopeptide repeat FNIP PF05725.7 EGC39316.1 - 8e-102 333.0 62.3 2.7e-14 52.8 0.0 11.4 7 2 1 11 11 11 11 FNIP Repeat DUF1769 PF08588.5 EGC39316.1 - 0.0013 18.6 17.1 13 5.8 0.1 9.2 9 2 3 12 12 12 2 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC39316.1 - 0.0052 16.7 0.0 46 4.0 0.0 5.0 4 2 2 6 6 6 0 Phage minor tail protein DUF3066 PF11266.3 EGC39316.1 - 0.022 14.4 0.0 2.5 7.7 0.0 3.1 3 0 0 3 3 3 0 Protein of unknown function (DUF3066) LRR_4 PF12799.2 EGC39316.1 - 3.6 7.3 8.0 2.3 7.9 0.1 3.7 2 1 1 3 3 3 0 Leucine Rich repeats (2 copies) zf-RING_2 PF13639.1 EGC39317.1 - 7e-13 48.1 6.7 1.1e-12 47.5 4.6 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC39317.1 - 3.7e-08 32.8 7.1 6.2e-08 32.1 4.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39317.1 - 7.5e-08 32.2 8.3 1.2e-07 31.5 5.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39317.1 - 4.3e-07 29.9 8.2 1.7e-06 28.0 5.7 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC39317.1 - 5.3e-06 26.0 5.0 8.3e-06 25.3 3.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39317.1 - 8.7e-06 25.3 4.6 1.3e-05 24.8 3.2 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC39317.1 - 0.0026 17.5 4.2 0.01 15.6 2.9 1.9 1 1 1 2 2 2 1 Anaphase-promoting complex subunit 11 RING-H2 finger RINGv PF12906.2 EGC39317.1 - 0.017 15.1 4.1 0.035 14.1 2.9 1.5 1 1 0 1 1 1 0 RING-variant domain Prok-RING_1 PF14446.1 EGC39317.1 - 0.21 11.3 6.4 0.12 12.1 0.9 2.1 1 1 1 2 2 2 0 Prokaryotic RING finger family 1 zf-Nse PF11789.3 EGC39317.1 - 0.31 10.5 4.5 0.52 9.8 3.1 1.3 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_UBOX PF13445.1 EGC39317.1 - 0.36 10.5 4.8 0.38 10.5 1.3 2.4 1 1 1 2 2 2 0 RING-type zinc-finger FANCL_C PF11793.3 EGC39317.1 - 0.51 10.3 7.7 3.6 7.6 5.3 2.3 1 1 0 1 1 1 0 FANCL C-terminal domain Ribosomal_L28 PF00830.14 EGC39317.1 - 3.9 7.3 5.9 8.3 6.3 4.1 1.5 1 0 0 1 1 1 0 Ribosomal L28 family FNIP PF05725.7 EGC39318.1 - 1.8e-78 258.2 38.9 6.5e-14 51.6 0.1 9.0 4 2 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC39318.1 - 0.00028 20.7 10.4 25 4.8 0.0 7.2 5 3 3 8 8 8 3 Protein of unknown function (DUF1769) BCAS2 PF05700.6 EGC39319.1 - 1.1e-60 204.8 17.9 1.3e-60 204.6 12.4 1.0 1 0 0 1 1 1 1 Breast carcinoma amplified sequence 2 (BCAS2) MaoC_dehydratas PF01575.14 EGC39320.1 - 4.1e-21 74.6 0.0 1e-20 73.3 0.0 1.7 1 0 0 1 1 1 1 MaoC like domain SET PF00856.23 EGC39320.1 - 7.8e-14 52.2 0.3 1e-09 38.8 0.0 2.9 3 0 0 3 3 3 2 SET domain TPR_11 PF13414.1 EGC39320.1 - 6.2e-12 44.9 0.0 1.1e-06 28.2 0.0 2.5 2 0 0 2 2 2 2 TPR repeat TPR_1 PF00515.23 EGC39320.1 - 2.1e-09 36.6 0.2 0.0058 16.1 0.0 3.4 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39320.1 - 1.4e-05 24.6 0.1 0.047 13.6 0.0 3.2 3 0 0 3 3 3 2 Tetratricopeptide repeat MaoC_dehydrat_N PF13452.1 EGC39320.1 - 2.9e-05 23.8 0.0 6.7e-05 22.6 0.0 1.6 1 0 0 1 1 1 1 N-terminal half of MaoC dehydratase Apc3 PF12895.2 EGC39320.1 - 0.00021 21.3 0.1 0.00053 20.0 0.0 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex, cyclosome, subunit 3 TPR_12 PF13424.1 EGC39320.1 - 0.00021 21.1 0.1 0.00066 19.5 0.0 1.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC39320.1 - 0.00023 20.9 0.0 0.063 13.1 0.0 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_8 PF13181.1 EGC39320.1 - 0.00098 18.7 0.1 0.07 12.9 0.0 3.3 3 0 0 3 3 3 1 Tetratricopeptide repeat TPR_16 PF13432.1 EGC39320.1 - 0.0016 19.0 0.0 0.043 14.5 0.0 2.2 1 1 1 2 2 2 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC39320.1 - 0.0057 16.9 0.0 0.013 15.7 0.0 1.6 1 0 0 1 1 1 1 Tetratricopeptide repeat zf-MYND PF01753.13 EGC39320.1 - 0.016 15.1 1.2 0.016 15.1 0.8 2.2 3 0 0 3 3 2 0 MYND finger TPR_20 PF14561.1 EGC39320.1 - 0.019 15.0 0.0 6 7.0 0.0 2.7 1 1 1 2 2 2 0 Tetratricopeptide repeat TPR_21 PF09976.4 EGC39320.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.3 1 0 0 1 1 1 0 Tetratricopeptide repeat Pkinase_Tyr PF07714.12 EGC39321.1 - 1.2e-48 165.5 0.0 1.9e-48 164.7 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC39321.1 - 4.4e-46 157.1 0.0 8.2e-46 156.2 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Ank_2 PF12796.2 EGC39321.1 - 2e-34 117.7 3.6 4.4e-13 49.3 0.2 3.4 1 1 2 3 3 3 3 Ankyrin repeats (3 copies) Ank_4 PF13637.1 EGC39321.1 - 1.4e-31 108.2 3.7 1.8e-06 28.2 0.0 6.4 2 2 4 6 6 6 6 Ankyrin repeats (many copies) Ank PF00023.25 EGC39321.1 - 1.4e-28 97.2 1.0 1.1e-05 24.9 0.0 6.2 6 0 0 6 6 6 5 Ankyrin repeat Ank_5 PF13857.1 EGC39321.1 - 2.7e-24 84.6 5.2 5.6e-09 35.9 0.0 5.0 4 1 1 5 5 5 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC39321.1 - 6.6e-23 78.5 1.3 0.0018 18.3 0.0 6.1 5 0 0 5 5 5 4 Ankyrin repeat SAM_1 PF00536.25 EGC39321.1 - 6.6e-12 45.4 0.2 1.9e-11 43.9 0.2 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) SAM_2 PF07647.12 EGC39321.1 - 3.9e-06 26.6 0.2 9.9e-06 25.3 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) APH PF01636.18 EGC39321.1 - 0.11 12.1 0.1 0.26 10.9 0.0 1.6 1 0 0 1 1 1 0 Phosphotransferase enzyme family CBM49 PF09478.5 EGC39322.1 - 3.4e-12 46.2 0.2 5e-12 45.7 0.2 1.2 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 PLRV_ORF5 PF01690.12 EGC39322.1 - 3.4 6.6 6.7 5.2 6.0 4.7 1.2 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein FNIP PF05725.7 EGC39323.1 - 1.9e-79 261.3 47.2 5.3e-14 51.8 0.3 8.7 5 2 3 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC39323.1 - 8e-06 25.7 14.8 0.38 10.7 0.0 7.5 5 4 5 10 10 10 2 Protein of unknown function (DUF1769) DEAD PF00270.24 EGC39324.1 - 1.8e-14 53.5 0.0 7.5e-14 51.5 0.0 2.1 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC39324.1 - 9.2e-11 41.4 0.4 7.4e-10 38.5 0.0 2.5 2 0 0 2 2 2 1 Helicase conserved C-terminal domain HHH_5 PF14520.1 EGC39324.1 - 1.7e-08 34.5 0.1 3.9e-08 33.3 0.1 1.6 1 0 0 1 1 1 1 Helix-hairpin-helix domain DUF4332 PF14229.1 EGC39324.1 - 0.0035 17.2 0.0 0.012 15.5 0.0 1.9 1 0 0 1 1 1 1 Domain of unknown function (DUF4332) Helicase_C_2 PF13307.1 EGC39324.1 - 0.032 14.1 0.0 0.14 12.1 0.0 2.1 2 0 0 2 2 2 0 Helicase C-terminal domain CBF PF03914.12 EGC39325.1 - 2e-31 108.6 0.5 2e-31 108.6 0.3 4.4 6 1 1 7 7 7 1 CBF/Mak21 family RTTN_N PF14726.1 EGC39325.1 - 0.35 11.4 5.1 6.8 7.3 0.2 3.6 3 1 0 3 3 3 0 Rotatin, an armadillo repeat protein, centriole functioning CLTH PF10607.4 EGC39326.1 - 7.5e-40 135.9 2.7 1e-39 135.5 1.9 1.2 1 0 0 1 1 1 1 CTLH/CRA C-terminal to LisH motif domain LisH PF08513.6 EGC39326.1 - 2e-09 36.8 1.0 4e-09 35.8 0.1 2.0 2 0 0 2 2 2 1 LisH HSP90 PF00183.13 EGC39326.1 - 0.0002 19.8 0.3 0.00031 19.2 0.2 1.2 1 0 0 1 1 1 1 Hsp90 protein Thymidylate_kin PF02223.12 EGC39326.1 - 0.001 18.5 0.1 0.0014 18.0 0.1 1.2 1 0 0 1 1 1 1 Thymidylate kinase TINF2_N PF14973.1 EGC39326.1 - 0.048 13.7 0.8 0.13 12.4 0.1 2.1 2 1 1 3 3 3 0 TERF1-interacting nuclear factor 2 N-terminus Mic1 PF07035.7 EGC39326.1 - 0.086 12.2 0.6 0.53 9.6 0.1 2.2 1 1 1 2 2 2 0 Colon cancer-associated protein Mic1-like Streptin-Immun PF11083.3 EGC39326.1 - 0.45 10.5 4.6 0.41 10.6 1.0 2.4 1 1 0 2 2 2 0 Lantibiotic streptin immunity protein BAF1_ABF1 PF04684.8 EGC39327.1 - 0.015 14.1 3.0 0.017 13.9 2.1 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor DUF4200 PF13863.1 EGC39327.1 - 0.031 14.2 8.3 0.043 13.7 5.8 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4200) Pam17 PF08566.5 EGC39327.1 - 0.066 12.9 0.4 0.15 11.7 0.0 1.6 1 1 0 1 1 1 0 Mitochondrial import protein Pam17 DUF4175 PF13779.1 EGC39327.1 - 0.12 10.0 2.9 0.15 9.7 2.0 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF3811 PF11656.3 EGC39327.1 - 0.33 11.0 0.2 0.33 11.0 0.1 2.0 1 1 1 2 2 2 0 YjbD family (DUF3811) Med3 PF11593.3 EGC39327.1 - 0.97 8.5 7.7 1.5 8.0 5.4 1.2 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal E_Pc_C PF06752.7 EGC39327.1 - 2.3 7.6 6.2 3.1 7.2 4.3 1.2 1 0 0 1 1 1 0 Enhancer of Polycomb C-terminus Mid2 PF04478.7 EGC39328.1 - 0.00023 20.5 0.5 0.00066 19.1 0.4 1.8 1 0 0 1 1 1 1 Mid2 like cell wall stress sensor FHA PF00498.21 EGC39329.1 - 2e-18 66.2 0.2 5.1e-18 64.9 0.1 1.8 1 0 0 1 1 1 1 FHA domain zf-RING_2 PF13639.1 EGC39329.1 - 0.00014 21.6 15.9 0.00014 21.6 11.0 3.4 2 1 0 2 2 2 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39329.1 - 0.00061 19.4 12.8 0.00061 19.4 8.8 4.0 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39329.1 - 0.0021 17.6 16.4 0.0021 17.6 11.4 3.2 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39329.1 - 0.0067 16.4 17.5 0.0067 16.4 12.1 3.5 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGC39329.1 - 0.22 11.3 11.2 0.3 10.8 5.1 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein Ndc1_Nup PF09531.5 EGC39329.1 - 1.1 7.6 4.5 1.5 7.1 3.1 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Ndc1_Nup PF09531.5 EGC39331.1 - 3.8 5.8 19.1 4.5 5.5 13.3 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup PGAP1 PF07819.8 EGC39332.1 - 9.9e-09 35.1 0.3 1.7e-08 34.3 0.2 1.3 1 0 0 1 1 1 1 PGAP1-like protein DUF676 PF05057.9 EGC39332.1 - 2.8e-08 33.3 0.2 4.9e-08 32.5 0.2 1.5 1 1 0 1 1 1 1 Putative serine esterase (DUF676) Abhydrolase_1 PF00561.15 EGC39332.1 - 1.2e-06 28.2 0.0 1.4e-06 28.0 0.0 1.3 1 1 0 1 1 1 1 alpha/beta hydrolase fold LCAT PF02450.10 EGC39332.1 - 0.00011 21.2 0.0 0.00018 20.6 0.0 1.2 1 0 0 1 1 1 1 Lecithin:cholesterol acyltransferase Abhydrolase_6 PF12697.2 EGC39332.1 - 0.00017 21.5 0.0 0.00021 21.2 0.0 1.3 1 0 0 1 1 1 1 Alpha/beta hydrolase family DUF915 PF06028.6 EGC39332.1 - 0.0008 18.5 0.1 0.0028 16.7 0.0 1.8 2 0 0 2 2 2 1 Alpha/beta hydrolase of unknown function (DUF915) DUF900 PF05990.7 EGC39332.1 - 0.0015 17.8 0.1 0.0024 17.2 0.1 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF900) Abhydrolase_5 PF12695.2 EGC39332.1 - 0.0029 17.3 0.0 0.0039 16.9 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family DEAD PF00270.24 EGC39333.1 - 2.1e-46 157.4 0.0 4.5e-46 156.4 0.0 1.6 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC39333.1 - 7.1e-24 83.4 0.0 1.5e-23 82.4 0.0 1.6 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC39333.1 - 5e-05 23.1 0.3 0.00042 20.1 0.0 2.5 3 0 0 3 3 3 1 Type III restriction enzyme, res subunit Histone PF00125.19 EGC39333.1 - 0.025 14.6 0.0 0.074 13.1 0.0 1.7 2 0 0 2 2 2 0 Core histone H2A/H2B/H3/H4 WD40 PF00400.27 EGC39334.1 - 6.2e-51 168.5 41.7 1.8e-09 37.1 0.4 11.0 10 0 0 10 10 10 7 WD domain, G-beta repeat AAA_22 PF13401.1 EGC39334.1 - 9.4e-10 38.7 0.0 7.1e-09 35.8 0.0 2.4 2 0 0 2 2 2 1 AAA domain DUF4062 PF13271.1 EGC39334.1 - 5.2e-09 35.9 0.9 2.4e-08 33.8 0.0 2.6 2 1 0 2 2 1 1 Domain of unknown function (DUF4062) AAA_16 PF13191.1 EGC39334.1 - 7.5e-09 35.8 0.3 5.7e-08 32.9 0.0 2.4 2 1 0 2 2 1 1 AAA ATPase domain NB-ARC PF00931.17 EGC39334.1 - 1.2e-06 27.6 1.4 1.7e-06 27.1 0.1 1.9 2 0 0 2 2 2 1 NB-ARC domain Arch_ATPase PF01637.13 EGC39334.1 - 1.3e-06 28.2 0.1 1.3e-06 28.2 0.1 2.6 2 1 0 2 2 2 1 Archaeal ATPase NACHT PF05729.7 EGC39334.1 - 6.7e-06 25.8 0.0 2.7e-05 23.9 0.0 2.0 1 1 0 1 1 1 1 NACHT domain Ish1 PF10281.4 EGC39334.1 - 1.5e-05 24.9 0.5 7.2e-05 22.7 0.3 2.3 1 0 0 1 1 1 1 Putative stress-responsive nuclear envelope protein AAA PF00004.24 EGC39334.1 - 3.6e-05 23.9 0.0 0.00024 21.3 0.0 2.6 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) BBS2_Mid PF14783.1 EGC39334.1 - 0.00032 20.4 0.1 5.3 6.8 0.0 4.4 3 1 0 3 3 3 2 Ciliary BBSome complex subunit 2, middle region Miro PF08477.8 EGC39334.1 - 0.00035 21.0 0.1 0.0029 18.0 0.1 2.7 1 1 0 1 1 1 1 Miro-like protein AAA_24 PF13479.1 EGC39334.1 - 0.0027 17.3 0.2 0.0077 15.8 0.1 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC39334.1 - 0.016 16.0 0.0 0.072 13.9 0.0 2.2 1 0 0 1 1 1 0 AAA domain AAA_assoc_C PF09821.4 EGC39334.1 - 0.045 14.0 0.0 0.15 12.3 0.0 1.9 1 0 0 1 1 1 0 C-terminal AAA-associated domain AAA_14 PF13173.1 EGC39334.1 - 0.066 13.1 3.4 0.49 10.2 0.3 3.4 2 1 0 2 2 2 0 AAA domain AAA_25 PF13481.1 EGC39334.1 - 0.077 12.3 0.0 0.24 10.7 0.0 1.8 1 1 0 1 1 1 0 AAA domain AAA_30 PF13604.1 EGC39334.1 - 0.18 11.3 0.0 0.31 10.5 0.0 1.3 1 0 0 1 1 1 0 AAA domain T2SE PF00437.15 EGC39334.1 - 0.21 10.4 0.0 0.49 9.2 0.0 1.6 1 0 0 1 1 1 0 Type II/IV secretion system protein AAA_19 PF13245.1 EGC39334.1 - 0.27 11.0 0.0 0.53 10.0 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain FNIP PF05725.7 EGC39335.1 - 2.2e-151 491.6 65.9 1.2e-15 57.1 0.3 9.5 2 1 9 13 13 13 13 FNIP Repeat Phage_min_tail PF05939.8 EGC39335.1 - 1.4e-07 31.3 0.0 6.1 6.8 0.0 7.0 2 2 7 9 9 9 2 Phage minor tail protein LRR_5 PF13306.1 EGC39335.1 - 0.0081 15.8 0.8 0.4 10.3 0.0 3.6 2 2 1 3 3 3 1 Leucine rich repeats (6 copies) Shigella_OspC PF06128.6 EGC39335.1 - 0.078 12.4 10.1 4.1 6.8 0.0 4.8 2 1 3 5 5 5 0 Shigella flexneri OspC protein FNIP PF05725.7 EGC39336.1 - 3e-181 587.2 69.1 1.9e-15 56.5 0.2 14.4 10 3 7 17 17 17 16 FNIP Repeat LRR_5 PF13306.1 EGC39336.1 - 0.012 15.3 2.2 1.5 8.5 0.0 4.5 3 2 1 4 4 4 0 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC39337.1 - 2.7e-31 107.2 7.4 2.8e-15 55.9 0.1 3.0 1 1 0 3 3 3 3 FNIP Repeat LRR_6 PF13516.1 EGC39337.1 - 0.0058 16.5 0.8 38 4.7 0.0 3.9 4 0 0 4 4 4 0 Leucine Rich repeat DUF1769 PF08588.5 EGC39337.1 - 0.031 14.2 9.4 2.8 7.9 0.1 3.9 1 1 3 4 4 4 0 Protein of unknown function (DUF1769) Rsa3 PF14615.1 EGC39337.1 - 1.7 8.0 4.8 13 5.1 0.2 2.8 3 0 0 3 3 3 0 Ribosome-assembly protein 3 FNIP PF05725.7 EGC39338.1 - 1.4e-153 498.6 55.2 6.9e-16 57.9 0.1 12.3 12 0 0 12 12 12 12 FNIP Repeat DUF1662 PF07878.6 EGC39338.1 - 0.02 14.5 0.2 17 5.2 0.0 5.4 7 0 0 7 7 7 0 Protein of unknown function (DUF1662) DUF1769 PF08588.5 EGC39338.1 - 0.1 12.5 50.0 15 5.6 0.2 13.8 6 5 10 17 17 17 0 Protein of unknown function (DUF1769) ATP-synt PF00231.14 EGC39339.1 - 0.12 11.7 1.4 0.12 11.6 0.9 1.0 1 0 0 1 1 1 0 ATP synthase tRNA-synt_1 PF00133.17 EGC39340.1 - 4.7e-178 592.9 0.9 6.6e-178 592.4 0.6 1.1 1 0 0 1 1 1 1 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC39340.1 - 3e-25 88.7 0.6 7.5e-25 87.4 0.4 1.7 1 0 0 1 1 1 1 Anticodon-binding domain of tRNA tRNA-synt_1g PF09334.6 EGC39340.1 - 8.1e-25 87.2 0.2 2.2e-14 52.9 0.0 3.7 3 0 0 3 3 3 3 tRNA synthetases class I (M) tRNA-synt_1_2 PF13603.1 EGC39340.1 - 0.00015 21.1 0.0 0.0023 17.2 0.0 2.4 2 0 0 2 2 2 1 Leucyl-tRNA synthetase, Domain 2 zf-FPG_IleRS PF06827.9 EGC39340.1 - 0.01 15.4 4.3 0.019 14.5 3.0 1.5 1 0 0 1 1 1 0 Zinc finger found in FPG and IleRS MFS_1 PF07690.11 EGC39341.1 - 5e-27 94.5 35.6 8.8e-27 93.7 20.3 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily MFS_2 PF13347.1 EGC39341.1 - 7.8e-15 54.1 21.5 8.9e-15 54.0 12.9 2.0 2 0 0 2 2 2 1 MFS/sugar transport protein FNIP PF05725.7 EGC39342.1 - 3.3e-141 459.0 37.9 1.4e-15 56.9 0.1 11.5 5 3 2 11 11 11 11 FNIP Repeat DUF3215 PF11503.3 EGC39342.1 - 0.044 13.4 0.7 9.6 5.9 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF3215) Terminase_1 PF03354.10 EGC39342.1 - 0.083 11.2 0.1 0.12 10.7 0.1 1.1 1 0 0 1 1 1 0 Phage Terminase DUF3608 PF12257.3 EGC39343.1 - 3e-71 239.5 1.8 6.6e-71 238.4 1.3 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3608) DEP PF00610.16 EGC39343.1 - 1.5e-17 63.0 0.1 3.6e-17 61.8 0.0 1.7 1 0 0 1 1 1 1 Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) Dimer_Tnp_hAT PF05699.9 EGC39344.1 - 1.5e-15 56.5 0.6 2.2e-15 56.0 0.4 1.2 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region Peptidase_M24 PF00557.19 EGC39345.1 - 1.5e-26 93.2 0.3 2e-26 92.8 0.2 1.3 1 1 0 1 1 1 1 Metallopeptidase family M24 Con-6 PF10346.4 EGC39345.1 - 0.094 12.1 0.0 0.26 10.7 0.0 1.8 1 0 0 1 1 1 0 Conidiation protein 6 DUF1289 PF06945.8 EGC39346.1 - 8e-21 73.2 1.7 9.6e-21 73.0 1.2 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1289) FeoB_N PF02421.13 EGC39346.1 - 0.12 11.7 0.0 0.18 11.0 0.0 1.4 2 0 0 2 2 2 0 Ferrous iron transport protein B CFIA_Pcf11 PF11526.3 EGC39346.1 - 0.12 12.5 0.0 0.15 12.1 0.0 1.2 1 0 0 1 1 1 0 Subunit of cleavage factor IA Pcf11 Acetyltransf_2 PF00797.12 EGC39347.1 - 0.00095 18.8 0.1 0.0012 18.4 0.0 1.3 1 0 0 1 1 1 1 N-acetyltransferase GTP_EFTU PF00009.22 EGC39348.1 - 3e-22 78.9 0.0 6.6e-22 77.8 0.0 1.5 1 0 0 1 1 1 1 Elongation factor Tu GTP binding domain GTP_EFTU_D3 PF03143.12 EGC39348.1 - 1.2e-13 51.0 0.1 1.2e-13 51.0 0.1 2.9 3 0 0 3 3 3 1 Elongation factor Tu C-terminal domain GTP_EFTU_D2 PF03144.20 EGC39348.1 - 9.5e-11 41.6 3.2 2.6e-10 40.2 2.2 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 2 GTP_EFTU_D4 PF14578.1 EGC39348.1 - 0.00051 19.6 1.3 0.0015 18.1 0.9 1.9 1 0 0 1 1 1 1 Elongation factor Tu domain 4 MMR_HSR1 PF01926.18 EGC39348.1 - 0.0029 17.5 1.8 0.0069 16.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC39348.1 - 0.0065 15.9 0.0 23 4.4 0.0 3.4 2 1 1 3 3 3 0 Ethanolamine utilisation - propanediol utilisation Arf PF00025.16 EGC39348.1 - 0.02 14.1 1.4 5.1 6.3 0.0 3.6 3 0 0 3 3 3 0 ADP-ribosylation factor family ImcF-related_N PF14331.1 EGC39348.1 - 0.12 11.2 0.0 2 7.2 0.0 2.2 2 0 0 2 2 2 0 ImcF-related N-terminal domain Miro PF08477.8 EGC39348.1 - 0.89 10.0 5.3 0.66 10.4 0.1 3.4 3 2 2 5 5 5 0 Miro-like protein Band_7 PF01145.20 EGC39349.1 - 2.3e-28 99.2 4.8 1.8e-27 96.4 3.1 2.3 1 1 0 1 1 1 1 SPFH domain / Band 7 family DUF1822 PF08852.6 EGC39349.1 - 0.002 17.0 1.4 0.0029 16.4 0.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF1822) DivIVA PF05103.8 EGC39349.1 - 0.031 14.3 5.3 0.057 13.4 3.6 1.4 1 0 0 1 1 1 0 DivIVA protein Hist_deacetyl PF00850.14 EGC39350.1 - 3.8e-92 308.9 0.0 3.8e-92 308.9 0.0 1.9 2 0 0 2 2 2 1 Histone deacetylase domain Zn_Tnp_IS1 PF03811.8 EGC39350.1 - 0.0011 18.3 4.1 0.0022 17.4 2.9 1.5 1 0 0 1 1 1 1 InsA N-terminal domain FNIP PF05725.7 EGC39351.1 - 8.8e-148 480.1 40.7 6.6e-15 54.7 0.0 11.2 9 1 1 11 11 11 11 FNIP Repeat Phage_min_tail PF05939.8 EGC39351.1 - 6.5e-06 26.0 0.7 11 5.9 0.0 7.7 2 2 7 9 9 9 1 Phage minor tail protein DUF3215 PF11503.3 EGC39351.1 - 0.016 14.8 0.0 0.48 10.1 0.0 3.7 2 0 0 2 2 2 0 Protein of unknown function (DUF3215) zf-met PF12874.2 EGC39352.1 - 5.7e-05 23.1 1.6 0.00017 21.6 1.1 1.9 1 0 0 1 1 1 1 Zinc-finger of C2H2 type zf-C2H2_jaz PF12171.3 EGC39352.1 - 0.00095 19.2 0.8 0.0019 18.2 0.5 1.6 1 0 0 1 1 1 1 Zinc-finger double-stranded RNA-binding ThiF PF00899.16 EGC39352.1 - 0.72 9.6 5.1 5.8 6.7 3.4 2.4 1 1 0 1 1 1 0 ThiF family zf-C3HC4_3 PF13920.1 EGC39354.1 - 2e-08 33.7 8.5 3.4e-08 33.0 5.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC39354.1 - 4.6e-08 32.7 9.6 8e-08 31.9 6.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC39354.1 - 6.6e-08 32.0 9.7 1.8e-07 30.6 6.7 1.9 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39354.1 - 1.7e-06 28.0 6.4 4.7e-06 26.6 4.4 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC39354.1 - 5.2e-06 26.3 9.8 9.7e-06 25.5 6.8 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC39354.1 - 0.002 17.9 8.1 0.0061 16.4 5.4 2.0 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC39354.1 - 0.01 15.5 10.2 0.021 14.5 7.0 1.5 1 0 0 1 1 1 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39354.1 - 0.063 12.8 6.7 0.18 11.3 4.6 1.9 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC39354.1 - 0.22 11.2 6.0 0.2 11.4 2.5 2.3 2 0 0 2 2 2 0 RING-type zinc-finger DZR PF12773.2 EGC39354.1 - 0.67 9.8 8.0 4.5 7.1 4.6 2.4 1 1 0 1 1 1 0 Double zinc ribbon Transglut_core PF01841.14 EGC39355.1 - 6.3e-14 52.1 0.0 3.5e-08 33.6 0.0 2.7 2 0 0 2 2 2 2 Transglutaminase-like superfamily PB1 PF00564.19 EGC39356.1 - 0.078 12.6 0.0 0.29 10.8 0.0 1.9 2 0 0 2 2 2 0 PB1 domain TetR_C_8 PF14278.1 EGC39356.1 - 5.9 7.3 9.7 0.42 11.0 1.6 3.1 3 1 0 3 3 3 0 Transcriptional regulator C-terminal region PH PF00169.24 EGC39357.1 - 3.8e-15 55.9 2.5 6.1e-13 48.8 0.3 2.4 2 1 0 2 2 2 2 PH domain PH_8 PF15409.1 EGC39357.1 - 1.8e-05 24.7 0.2 5e-05 23.2 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain PH_11 PF15413.1 EGC39357.1 - 0.0013 18.9 2.2 0.0013 18.9 1.5 3.1 2 2 0 2 2 2 1 Pleckstrin homology domain PH_6 PF15406.1 EGC39357.1 - 0.0021 18.1 0.0 0.0046 16.9 0.0 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH_10 PF15411.1 EGC39357.1 - 0.0075 16.4 0.1 0.022 14.9 0.1 1.8 1 0 0 1 1 1 1 Pleckstrin homology domain DUF2666 PF10869.3 EGC39357.1 - 0.027 14.4 3.7 0.045 13.7 1.2 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF2666) PH_9 PF15410.1 EGC39357.1 - 0.04 14.0 1.0 2.6 8.2 0.1 3.0 2 1 0 2 2 2 0 Pleckstrin homology domain Asp PF00026.18 EGC39358.1 - 4.4e-16 59.0 0.0 6.9e-16 58.3 0.0 1.2 1 0 0 1 1 1 1 Eukaryotic aspartyl protease TAXi_C PF14541.1 EGC39358.1 - 9.7e-15 54.4 0.0 1.5e-14 53.8 0.0 1.3 1 0 0 1 1 1 1 Xylanase inhibitor C-terminal TAXi_N PF14543.1 EGC39358.1 - 9.4e-07 28.9 0.1 1.8e-06 27.9 0.1 1.4 1 0 0 1 1 1 1 Xylanase inhibitor N-terminal SLAC1 PF03595.12 EGC39361.1 - 0.0019 16.8 3.0 0.0024 16.5 2.0 1.0 1 0 0 1 1 1 1 Voltage-dependent anion channel Tmemb_161AB PF10268.4 EGC39361.1 - 0.054 12.0 0.1 0.069 11.6 0.1 1.0 1 0 0 1 1 1 0 Predicted transmembrane protein 161AB DUF1705 PF08019.7 EGC39361.1 - 0.079 12.4 1.3 0.1 12.0 0.9 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF1705) Frag1 PF10277.4 EGC39361.1 - 0.19 11.2 6.8 0.24 10.8 4.7 1.2 1 0 0 1 1 1 0 Frag1/DRAM/Sfk1 family FNIP PF05725.7 EGC39362.1 - 4.1e-71 234.6 67.0 4.3e-10 39.3 0.8 10.0 4 2 8 12 12 12 12 FNIP Repeat DUF1673 PF07895.6 EGC39363.1 - 0.001 18.6 7.3 0.0016 18.0 5.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1673) Spore_III_AE PF09546.5 EGC39363.1 - 0.016 14.1 1.2 0.019 13.9 0.8 1.1 1 0 0 1 1 1 0 Stage III sporulation protein AE (spore_III_AE) DUF1361 PF07099.6 EGC39363.1 - 0.028 14.2 0.7 0.041 13.6 0.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1361) IBV_3C PF03620.8 EGC39363.1 - 0.058 13.3 1.3 0.092 12.6 0.8 1.3 1 1 0 1 1 1 0 IBV 3C protein DREPP PF05558.7 EGC39363.1 - 0.64 9.8 3.8 1.6 8.5 0.9 2.0 2 0 0 2 2 2 0 DREPP plasma membrane polypeptide FNIP PF05725.7 EGC39364.1 - 2e-96 315.7 31.1 5.5e-15 55.0 0.2 7.2 5 1 2 8 8 8 8 FNIP Repeat DUF3215 PF11503.3 EGC39364.1 - 0.087 12.4 0.2 11 5.6 0.0 3.7 3 1 1 4 4 4 0 Protein of unknown function (DUF3215) DUF1769 PF08588.5 EGC39364.1 - 2.7 7.9 23.1 6.6 6.7 0.1 7.9 3 2 5 10 10 10 0 Protein of unknown function (DUF1769) DUF4449 PF14613.1 EGC39365.1 - 0.0012 18.8 2.7 0.0012 18.8 1.8 2.4 2 0 0 2 2 2 1 Protein of unknown function (DUF4449) DUF4487 PF14868.1 EGC39366.1 - 0.13 10.9 0.0 0.15 10.7 0.0 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4487) FNIP PF05725.7 EGC39367.1 - 1.7e-110 360.7 31.5 2.2e-15 56.3 0.4 7.6 2 2 5 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC39367.1 - 0.08 12.9 27.6 15 5.6 0.1 9.2 3 1 10 13 13 13 0 Protein of unknown function (DUF1769) LRR_6 PF13516.1 EGC39367.1 - 0.64 10.2 19.6 2.2e+02 2.4 0.0 9.8 12 0 0 12 12 12 0 Leucine Rich repeat FNIP PF05725.7 EGC39368.1 - 5.1e-40 135.1 2.2 2.1e-15 56.3 0.1 3.0 2 1 0 3 3 3 3 FNIP Repeat DUF1769 PF08588.5 EGC39368.1 - 0.00096 19.0 5.5 0.98 9.4 0.1 4.0 1 1 3 4 4 4 2 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC39368.1 - 0.0024 17.7 0.0 1 9.3 0.0 3.0 1 1 1 3 3 3 1 Phage minor tail protein FNIP PF05725.7 EGC39369.1 - 1.6e-138 450.4 52.7 6e-16 58.1 0.5 11.9 5 3 3 12 12 12 12 FNIP Repeat DUF1769 PF08588.5 EGC39369.1 - 0.00065 19.6 35.2 2.8 7.9 0.1 11.6 5 4 9 14 14 14 4 Protein of unknown function (DUF1769) Ras PF00071.17 EGC39370.1 - 2.9e-59 199.0 0.0 3.4e-59 198.8 0.0 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39370.1 - 6e-21 75.1 0.0 8.6e-21 74.6 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39370.1 - 7.8e-18 64.3 0.0 1e-17 63.9 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC39370.1 - 1.2e-06 28.4 0.0 1.7e-06 27.9 0.0 1.2 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC39370.1 - 1.8e-06 27.4 0.0 1e-05 25.0 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain Gtr1_RagA PF04670.7 EGC39370.1 - 1.2e-05 24.5 0.0 1.6e-05 24.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region ATP_bind_1 PF03029.12 EGC39370.1 - 2.4e-05 23.9 0.0 0.0028 17.2 0.0 2.1 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EGC39370.1 - 0.0028 16.8 0.0 0.0048 16.1 0.0 1.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit FeoB_N PF02421.13 EGC39370.1 - 0.0085 15.3 0.0 0.13 11.5 0.0 2.1 1 1 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC39370.1 - 0.024 14.1 0.0 0.3 10.5 0.0 2.4 1 1 1 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_16 PF13191.1 EGC39370.1 - 0.092 12.7 0.2 0.19 11.7 0.1 1.6 1 1 0 1 1 1 0 AAA ATPase domain Rad17 PF03215.10 EGC39370.1 - 0.11 11.2 0.1 0.14 10.8 0.0 1.1 1 0 0 1 1 1 0 Rad17 cell cycle checkpoint protein zf-RING_2 PF13639.1 EGC39371.1 - 3.2e-09 36.4 7.7 5.3e-09 35.7 5.3 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39371.1 - 4.4e-09 35.8 5.9 6.9e-09 35.2 4.1 1.2 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39371.1 - 1.2e-08 34.4 9.3 2.2e-08 33.6 6.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39371.1 - 2.2e-07 30.7 9.3 3.6e-07 30.1 6.4 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39371.1 - 2e-06 27.8 6.6 7.5e-06 25.9 4.6 1.9 1 1 0 1 1 1 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC39371.1 - 8.1e-05 22.2 8.4 0.00035 20.2 6.0 1.9 1 1 1 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC39371.1 - 9.9e-05 22.1 1.8 0.00019 21.2 1.3 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC39371.1 - 0.00058 19.6 9.2 0.0013 18.6 6.4 1.6 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING FdhE PF04216.7 EGC39371.1 - 0.0076 16.0 0.5 0.011 15.5 0.3 1.3 1 0 0 1 1 1 1 Protein involved in formate dehydrogenase formation TerY-C PF15616.1 EGC39371.1 - 0.011 15.6 6.0 0.022 14.6 4.1 1.6 1 1 0 1 1 1 0 TerY-C metal binding domain zf-RING_4 PF14570.1 EGC39371.1 - 0.014 14.9 10.2 0.062 12.8 7.1 1.9 1 1 1 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC39371.1 - 0.014 15.0 2.9 0.03 14.0 0.7 2.4 1 1 1 2 2 2 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGC39371.1 - 0.054 13.2 2.9 0.1 12.3 2.0 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_3 PF14369.1 EGC39371.1 - 2.7 8.0 6.7 11 6.1 0.2 2.6 2 0 0 2 2 2 0 zinc-finger PI3K_1B_p101 PF10486.4 EGC39372.1 - 0.0018 15.9 3.5 0.0027 15.4 0.7 2.0 2 0 0 2 2 2 1 Phosphoinositide 3-kinase gamma adapter protein p101 subunit Nucleoplasmin PF03066.10 EGC39372.1 - 0.055 12.9 13.0 0.8 9.2 2.2 2.5 2 0 0 2 2 2 0 Nucleoplasmin Sigma70_ner PF04546.8 EGC39372.1 - 0.2 11.2 12.8 0.6 9.7 0.1 3.4 4 0 0 4 4 4 0 Sigma-70, non-essential region EST1 PF10374.4 EGC39372.1 - 1.4 8.9 9.6 1.3 9.0 0.0 4.2 5 1 0 5 5 5 0 Telomerase activating protein Est1 Sporozoite_P67 PF05642.6 EGC39372.1 - 1.6 6.4 6.4 1.2 6.9 0.1 2.3 2 0 0 2 2 2 0 Sporozoite P67 surface antigen Flavi_capsid PF01003.14 EGC39373.1 - 0.19 11.2 2.1 0.22 11.0 1.4 1.1 1 0 0 1 1 1 0 Flavivirus capsid protein C TrkH PF02386.11 EGC39374.1 - 4.1e-57 193.3 33.8 2.1e-53 181.1 14.6 3.2 2 1 0 2 2 2 2 Cation transport protein DUF2457 PF10446.4 EGC39374.1 - 3.3e-05 22.8 17.9 5.1e-05 22.1 12.4 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF2457) Pex14_N PF04695.8 EGC39374.1 - 0.00089 19.3 1.0 0.00089 19.3 0.7 2.0 2 0 0 2 2 2 1 Peroxisomal membrane anchor protein (Pex14p) conserved region Ras PF00071.17 EGC39375.1 - 8.7e-50 168.2 0.0 1.1e-49 167.9 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39375.1 - 2e-16 60.5 0.0 3e-16 59.9 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39375.1 - 5.7e-16 58.2 0.0 7.6e-16 57.8 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39375.1 - 4.1e-08 32.6 0.0 5.6e-08 32.2 0.0 1.3 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC39375.1 - 4.5e-05 22.9 0.0 0.00099 18.5 0.0 2.1 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC39375.1 - 0.00099 19.0 0.0 0.0016 18.3 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PduV-EutP PF10662.4 EGC39375.1 - 0.001 18.5 0.1 0.036 13.5 0.0 2.3 1 1 0 1 1 1 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC39375.1 - 0.0013 18.0 0.0 0.0017 17.5 0.0 1.3 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit G-alpha PF00503.15 EGC39375.1 - 0.01 14.5 0.0 0.014 14.1 0.0 1.4 1 1 0 1 1 1 0 G-protein alpha subunit DUF3430 PF11912.3 EGC39376.1 - 8.4e-33 113.9 28.3 8.4e-33 113.9 19.6 2.2 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) DUF3316 PF11777.3 EGC39376.1 - 0.0021 17.7 0.0 0.14 11.9 0.0 2.6 1 1 1 2 2 2 2 Protein of unknown function (DUF3316) Chitin_bind_3 PF03067.10 EGC39377.1 - 2.2e-06 28.0 0.6 0.00011 22.5 0.1 2.0 1 1 1 2 2 2 2 Chitin binding domain zf-HIT PF04438.11 EGC39378.1 - 2.2e-07 30.3 10.3 3.3e-07 29.8 7.2 1.3 1 0 0 1 1 1 1 HIT zinc finger zf-MYND PF01753.13 EGC39378.1 - 3.9e-05 23.4 9.2 6e-05 22.8 6.4 1.3 1 0 0 1 1 1 1 MYND finger AvrE PF11725.3 EGC39378.1 - 0.017 12.1 7.2 0.018 12.1 5.0 1.1 1 0 0 1 1 1 0 Pathogenicity factor Ebola_NP PF05505.7 EGC39378.1 - 0.02 12.9 13.8 0.022 12.8 9.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein Med24_N PF11277.3 EGC39378.1 - 0.028 11.9 3.0 0.034 11.6 2.1 1.1 1 0 0 1 1 1 0 Mediator complex subunit 24 N-terminal zf-Mss51 PF13824.1 EGC39378.1 - 0.052 13.4 6.0 0.16 11.8 4.2 1.8 1 0 0 1 1 1 0 Zinc-finger of mitochondrial splicing suppressor 51 DUF605 PF04652.11 EGC39378.1 - 0.14 11.5 15.8 0.17 11.2 11.0 1.1 1 0 0 1 1 1 0 Vta1 like Neur_chan_memb PF02932.11 EGC39378.1 - 1 9.1 5.7 1.3 8.8 3.9 1.2 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region DUF1510 PF07423.6 EGC39378.1 - 3.2 7.0 17.1 4.1 6.7 11.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) NESP55 PF06390.7 EGC39378.1 - 3.4 6.9 13.1 4.7 6.5 9.1 1.2 1 0 0 1 1 1 0 Neuroendocrine-specific golgi protein P55 (NESP55) Trypan_PARP PF05887.6 EGC39378.1 - 5.2 6.8 12.4 8.7 6.1 8.6 1.3 1 0 0 1 1 1 0 Procyclic acidic repetitive protein (PARP) Paramyxo_ncap PF00973.14 EGC39378.1 - 6.8 5.2 8.6 8.2 4.9 6.0 1.1 1 0 0 1 1 1 0 Paramyxovirus nucleocapsid protein Ndc1_Nup PF09531.5 EGC39378.1 - 9.7 4.4 7.5 11 4.3 5.2 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup HutD PF05962.6 EGC39379.1 - 3.1e-27 95.5 0.0 3e-23 82.4 0.0 2.4 2 1 0 2 2 2 2 HutD DUF1312 PF07009.6 EGC39379.1 - 0.15 11.9 1.8 0.65 9.8 0.1 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1312) RRM_1 PF00076.17 EGC39380.1 - 2.9e-22 78.0 0.2 3.4e-22 77.8 0.1 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC39380.1 - 3.1e-16 59.1 0.0 4e-16 58.7 0.0 1.1 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC39380.1 - 5.5e-12 45.3 0.3 6.7e-12 45.0 0.2 1.1 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Calcipressin PF04847.7 EGC39380.1 - 0.0034 16.9 0.0 0.0038 16.8 0.0 1.2 1 0 0 1 1 1 1 Calcipressin Nup35_RRM_2 PF14605.1 EGC39380.1 - 0.028 14.2 0.0 0.04 13.6 0.0 1.2 1 0 0 1 1 1 0 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGC39380.1 - 0.051 13.3 0.1 0.08 12.7 0.1 1.3 1 1 0 1 1 1 0 Limkain b1 TCTP PF00838.12 EGC39381.1 - 6.1e-51 172.6 4.0 6.9e-51 172.5 2.8 1.0 1 0 0 1 1 1 1 Translationally controlled tumour protein tRNA_int_endo PF01974.12 EGC39382.1 - 2.5e-21 75.2 0.5 5.6e-21 74.1 0.1 1.8 2 0 0 2 2 2 1 tRNA intron endonuclease, catalytic C-terminal domain tRNA_int_endo_N PF02778.9 EGC39382.1 - 6e-07 28.9 0.2 0.00012 21.5 0.0 2.6 2 0 0 2 2 2 2 tRNA intron endonuclease, N-terminal domain E1-E2_ATPase PF00122.15 EGC39383.1 - 6.2e-60 202.0 1.5 9.8e-60 201.4 0.3 1.9 2 0 0 2 2 2 1 E1-E2 ATPase Hydrolase PF00702.21 EGC39383.1 - 1.1e-26 94.5 0.0 1.8e-26 93.9 0.0 1.3 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC39383.1 - 2.1e-13 50.8 0.0 5.4e-13 49.5 0.0 1.7 1 0 0 1 1 1 1 haloacid dehalogenase-like hydrolase Cation_ATPase_N PF00690.21 EGC39383.1 - 7.6e-12 44.5 0.0 1.7e-11 43.3 0.0 1.6 1 0 0 1 1 1 1 Cation transporter/ATPase, N-terminus Hydrolase_3 PF08282.7 EGC39383.1 - 0.00013 21.6 0.1 0.00077 19.1 0.1 2.2 2 0 0 2 2 2 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC39383.1 - 0.0021 17.9 0.0 0.0046 16.8 0.0 1.6 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit Dispanin PF04505.7 EGC39383.1 - 0.06 12.8 0.3 0.23 11.0 0.2 2.0 1 0 0 1 1 1 0 Interferon-induced transmembrane protein Thioredoxin PF00085.15 EGC39384.1 - 1.5e-10 40.7 0.1 1.6e-10 40.5 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Thioredoxin PF00085.15 EGC39385.1 - 2.6e-06 27.0 0.1 2.7e-06 26.9 0.0 1.0 1 0 0 1 1 1 1 Thioredoxin Snf7 PF03357.16 EGC39387.1 - 7e-40 136.1 32.5 8.2e-40 135.9 22.5 1.0 1 0 0 1 1 1 1 Snf7 Ist1 PF03398.9 EGC39387.1 - 0.03 13.7 8.8 0.043 13.2 6.1 1.3 1 0 0 1 1 1 0 Regulator of Vps4 activity in the MVB pathway Phage_X PF05155.10 EGC39387.1 - 0.049 13.5 1.0 0.48 10.3 0.2 2.5 2 1 1 3 3 3 0 Phage X family DMAP1 PF05499.7 EGC39388.1 - 0.067 12.7 0.1 0.072 12.6 0.1 1.1 1 0 0 1 1 1 0 DNA methyltransferase 1-associated protein 1 (DMAP1) Sec23_BS PF08033.7 EGC39389.1 - 1.4e-08 35.1 0.1 4.4e-08 33.5 0.0 1.9 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGC39389.1 - 5.1e-07 29.1 6.1 1.5e-06 27.6 4.2 1.8 1 1 0 1 1 1 1 Sec23/Sec24 zinc finger Sec23_helical PF04815.10 EGC39389.1 - 0.00093 18.5 3.2 0.0027 17.1 0.2 2.9 3 0 0 3 3 3 1 Sec23/Sec24 helical domain Gelsolin PF00626.17 EGC39389.1 - 0.0024 17.4 0.4 0.0097 15.5 0.0 2.2 2 0 0 2 2 2 1 Gelsolin repeat FYVE_2 PF02318.11 EGC39389.1 - 0.49 10.3 5.6 0.18 11.6 1.5 2.0 2 0 0 2 2 2 0 FYVE-type zinc finger PHD PF00628.24 EGC39389.1 - 0.5 10.0 4.3 1.1 9.0 3.0 1.5 1 0 0 1 1 1 0 PHD-finger FNIP PF05725.7 EGC39391.1 - 3.3e-08 33.3 2.8 4.5e-07 29.7 0.3 8.6 6 2 2 10 10 10 3 FNIP Repeat Ank_3 PF13606.1 EGC39391.1 - 0.0011 18.9 1.0 2.3 8.6 0.0 4.1 4 0 0 4 4 4 2 Ankyrin repeat TFIID_30kDa PF03540.8 EGC39391.1 - 0.62 9.9 2.2 23 4.8 0.0 3.3 3 0 0 3 3 3 0 Transcription initiation factor TFIID 23-30kDa subunit TRI5 PF06330.6 EGC39392.1 - 0.00023 19.9 0.9 0.00045 18.9 0.6 1.4 2 0 0 2 2 2 1 Trichodiene synthase (TRI5) GalP_UDP_tr_C PF02744.12 EGC39393.1 - 2e-05 24.1 0.0 9.2e-05 22.0 0.0 1.9 1 1 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, C-terminal domain GalP_UDP_transf PF01087.17 EGC39393.1 - 0.00071 19.6 0.1 0.0016 18.5 0.0 1.6 1 0 0 1 1 1 1 Galactose-1-phosphate uridyl transferase, N-terminal domain CwfJ_C_1 PF04677.10 EGC39394.1 - 0.042 13.5 0.8 0.11 12.0 0.6 1.8 1 0 0 1 1 1 0 Protein similar to CwfJ C-terminus 1 DUF1451 PF07295.6 EGC39394.1 - 0.15 11.8 0.9 0.26 11.0 0.1 1.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1451) SapB_1 PF05184.10 EGC39395.1 - 1.3 8.8 8.0 0.36 10.6 0.9 2.9 2 2 0 2 2 2 0 Saposin-like type B, region 1 PEMT PF04191.8 EGC39396.1 - 7.1e-27 93.5 5.8 7.1e-27 93.5 4.0 2.0 3 0 0 3 3 3 1 Phospholipid methyltransferase Steroid_dh PF02544.11 EGC39396.1 - 0.046 13.4 0.3 0.046 13.4 0.2 2.4 2 1 0 2 2 2 0 3-oxo-5-alpha-steroid 4-dehydrogenase CreD PF06123.7 EGC39396.1 - 0.084 11.4 0.5 0.14 10.6 0.4 1.3 1 0 0 1 1 1 0 Inner membrane protein CreD FNIP PF05725.7 EGC39398.1 - 6.5e-32 109.2 5.2 2.9e-12 46.3 0.1 2.6 1 1 2 3 3 3 3 FNIP Repeat DUF1769 PF08588.5 EGC39398.1 - 0.0023 17.8 0.7 3.2 7.7 0.0 3.0 1 1 2 3 3 3 3 Protein of unknown function (DUF1769) CRAL_TRIO_2 PF13716.1 EGC39399.1 - 0.1 12.5 3.3 0.069 13.0 0.3 2.0 1 1 1 2 2 2 0 Divergent CRAL/TRIO domain DUF3582 PF12122.3 EGC39399.1 - 0.45 10.5 5.2 2.8 7.9 0.5 3.3 2 1 1 3 3 3 0 Protein of unknown function (DUF3582) OTU PF02338.14 EGC39400.1 - 1.1e-12 48.6 0.1 1.1e-12 48.6 0.1 2.5 2 0 0 2 2 2 1 OTU-like cysteine protease DUF605 PF04652.11 EGC39400.1 - 0.016 14.6 41.7 0.026 13.9 28.9 1.3 1 0 0 1 1 1 0 Vta1 like PAT1 PF09770.4 EGC39400.1 - 0.054 11.7 58.4 0.074 11.2 40.5 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Hex_IIIa PF02455.11 EGC39400.1 - 1.6 7.3 19.6 2.5 6.7 13.6 1.2 1 0 0 1 1 1 0 Hexon-associated protein (IIIa) TFIIA PF03153.8 EGC39400.1 - 1.6 8.5 42.4 2.4 7.9 29.4 1.2 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit zf-TRAF PF02176.13 EGC39401.1 - 3.1e-14 53.0 37.0 2.4e-11 43.8 5.8 4.0 2 2 3 5 5 5 4 TRAF-type zinc finger zf-C3HC4_3 PF13920.1 EGC39401.1 - 0.0073 15.9 1.5 0.0073 15.9 1.1 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39401.1 - 0.035 14.1 1.0 0.035 14.1 0.7 3.9 3 1 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC39401.1 - 0.25 10.9 23.3 0.13 11.8 1.3 3.3 1 1 2 3 3 3 0 Seven in absentia protein family AMPKBI PF04739.10 EGC39402.1 - 0.00056 19.7 3.1 0.0027 17.5 2.2 2.2 1 0 0 1 1 1 1 5'-AMP-activated protein kinase beta subunit, interation domain zf-CCCH PF00642.19 EGC39403.1 - 0.0012 18.5 1.4 0.0012 18.5 1.0 2.8 3 0 0 3 3 3 2 Zinc finger C-x8-C-x5-C-x3-H type (and similar) Pkinase PF00069.20 EGC39404.1 - 1e-68 231.3 0.1 3.1e-68 229.7 0.0 2.0 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39404.1 - 1.4e-54 184.9 0.0 8.8e-54 182.2 0.0 2.2 1 1 1 2 2 2 1 Protein tyrosine kinase PBD PF00786.23 EGC39404.1 - 4.7e-06 26.9 0.1 4.2e-05 23.8 0.0 2.8 1 0 0 1 1 1 1 P21-Rho-binding domain Kinase-like PF14531.1 EGC39404.1 - 5.6e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC39404.1 - 0.0046 16.7 0.0 0.56 9.8 0.1 2.2 1 1 1 2 2 2 2 Phosphotransferase enzyme family RIO1 PF01163.17 EGC39404.1 - 0.015 14.6 0.1 0.07 12.4 0.0 2.0 2 0 0 2 2 2 0 RIO1 family Fez1 PF06818.10 EGC39404.1 - 0.018 15.1 1.5 0.047 13.7 1.1 1.8 1 0 0 1 1 1 0 Fez1 YrbL-PhoP_reg PF10707.4 EGC39404.1 - 0.045 13.0 0.1 0.3 10.3 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL EMP70 PF02990.11 EGC39405.1 - 0.24 9.8 2.1 0.3 9.5 1.4 1.1 1 0 0 1 1 1 0 Endomembrane protein 70 DnaJ PF00226.26 EGC39406.1 - 1e-24 86.0 1.5 1e-24 86.0 1.0 1.9 2 0 0 2 2 2 1 DnaJ domain DUF3792 PF12670.2 EGC39406.1 - 0.0063 16.3 6.5 0.23 11.3 1.3 2.2 1 1 1 2 2 2 2 Protein of unknown function (DUF3792) HUN PF08729.5 EGC39407.1 - 9e-09 35.0 11.4 9e-09 35.0 7.9 3.0 3 0 0 3 3 3 1 HPC2 and ubinuclein domain Atrophin-1 PF03154.10 EGC39407.1 - 0.00066 17.9 14.1 0.00066 17.9 9.8 3.6 2 1 2 4 4 4 1 Atrophin-1 family Pyridoxal_deC PF00282.14 EGC39408.1 - 1.2e-20 73.3 0.0 1.9e-20 72.6 0.0 1.3 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGC39408.1 - 5.1e-17 61.6 0.1 4.4e-16 58.5 0.1 2.2 1 1 0 1 1 1 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGC39408.1 - 0.0001 21.3 0.0 0.00047 19.2 0.0 2.0 2 0 0 2 2 2 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGC39408.1 - 0.0005 19.2 0.1 0.00086 18.4 0.1 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGC39408.1 - 0.043 12.0 0.0 0.075 11.2 0.0 1.4 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme Tna_leader PF08053.6 EGC39408.1 - 0.048 13.0 0.0 0.12 11.7 0.0 1.7 1 0 0 1 1 1 0 Tryptophanese operon leader peptide Tetraspannin PF00335.15 EGC39409.1 - 0.36 10.0 4.8 0.5 9.6 3.4 1.2 1 0 0 1 1 1 0 Tetraspanin family Peptidase_M20 PF01546.23 EGC39410.1 - 7.7e-29 100.5 0.0 1.2e-28 99.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC39410.1 - 3e-16 59.1 0.0 6.4e-16 58.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase dimerisation domain CH PF00307.26 EGC39411.1 - 9.3e-14 51.3 0.1 9.3e-14 51.3 0.1 3.3 2 1 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC39411.1 - 0.0027 17.2 0.1 0.0027 17.2 0.1 3.8 3 1 0 4 4 4 1 CAMSAP CH domain PAT1 PF09770.4 EGC39411.1 - 3.2 5.8 68.3 4.5 5.3 47.4 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 YfhO PF09586.5 EGC39411.1 - 7 4.5 44.3 9 4.1 30.7 1.3 1 0 0 1 1 1 0 Bacterial membrane protein YfhO CH PF00307.26 EGC39412.1 - 1e-12 48.0 0.0 1.3e-12 47.7 0.0 1.1 1 0 0 1 1 1 1 Calponin homology (CH) domain RNA_GG_bind PF10258.4 EGC39413.1 - 0.00066 19.3 5.7 0.12 12.1 0.0 3.0 3 0 0 3 3 3 2 PHAX RNA-binding domain RepA_C PF04796.7 EGC39413.1 - 0.84 9.2 3.7 2.8 7.5 1.1 2.3 2 0 0 2 2 2 0 Plasmid encoded RepA protein DUF3437 PF11919.3 EGC39414.1 - 3.3e-25 87.6 0.2 8.7e-24 83.0 0.1 3.3 3 0 0 3 3 3 1 Domain of unknown function (DUF3437) DcuA_DcuB PF03605.9 EGC39415.1 - 0.0052 15.6 1.8 0.0067 15.3 1.2 1.1 1 0 0 1 1 1 1 Anaerobic c4-dicarboxylate membrane transporter DUF2207 PF09972.4 EGC39415.1 - 0.088 11.3 7.6 0.09 11.3 5.3 1.0 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) Arif-1 PF06770.6 EGC39415.1 - 0.089 12.1 2.2 0.11 11.8 1.5 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Glycoprotein_B PF00606.13 EGC39415.1 - 0.83 7.6 3.0 0.82 7.6 2.1 1.0 1 0 0 1 1 1 0 Herpesvirus Glycoprotein B DUF4064 PF13273.1 EGC39415.1 - 2.2 8.4 12.9 3.4 7.8 8.9 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4064) zf-DHHC PF01529.15 EGC39415.1 - 3.9 6.8 7.4 5.4 6.3 5.2 1.2 1 0 0 1 1 1 0 DHHC palmitoyltransferase DUF872 PF05915.7 EGC39415.1 - 5.3 6.9 7.4 2.3 8.1 3.0 1.8 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) DUF3816 PF12822.2 EGC39416.1 - 0.0032 17.3 2.7 0.0034 17.2 1.9 1.1 1 0 0 1 1 1 1 Protein of unknown function (DUF3816) Na_H_Exchanger PF00999.16 EGC39416.1 - 0.011 14.3 1.9 0.012 14.1 1.3 1.1 1 0 0 1 1 1 0 Sodium/hydrogen exchanger family Pox_A14 PF05767.7 EGC39416.1 - 0.016 15.1 3.2 0.028 14.3 2.2 1.4 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 SdpI PF13630.1 EGC39416.1 - 0.019 14.6 1.7 0.028 14.1 1.2 1.2 1 0 0 1 1 1 0 SdpI/YhfL protein family DUF3671 PF12420.3 EGC39416.1 - 0.033 14.1 5.7 0.047 13.6 4.0 1.2 1 0 0 1 1 1 0 Protein of unknown function Cytochrom_B_C PF00032.12 EGC39416.1 - 0.049 13.8 3.0 0.07 13.3 2.1 1.2 1 0 0 1 1 1 0 Cytochrome b(C-terminal)/b6/petD Oxidored_q4 PF00507.14 EGC39416.1 - 0.052 13.3 2.8 0.079 12.7 1.9 1.3 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 DUF2207 PF09972.4 EGC39416.1 - 0.057 12.0 1.9 0.062 11.8 1.3 1.1 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF3290 PF11694.3 EGC39416.1 - 0.059 13.1 2.0 0.11 12.2 1.4 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3290) Arif-1 PF06770.6 EGC39416.1 - 0.078 12.3 0.4 0.1 11.9 0.2 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) Tmemb_9 PF05434.6 EGC39416.1 - 0.091 12.5 5.8 0.06 13.0 2.5 1.7 2 0 0 2 2 2 0 TMEM9 ABC2_membrane_3 PF12698.2 EGC39416.1 - 0.098 11.6 7.8 0.082 11.9 4.6 1.4 1 1 0 1 1 1 0 ABC-2 family transporter protein Sec20 PF03908.8 EGC39416.1 - 0.14 11.8 1.6 3.2 7.5 0.3 2.2 2 0 0 2 2 2 0 Sec20 DUF485 PF04341.7 EGC39416.1 - 0.18 11.5 1.6 0.26 10.9 1.1 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF485 PMP22_Claudin PF00822.15 EGC39416.1 - 0.37 10.4 3.9 5.9 6.5 0.9 2.1 1 1 1 2 2 2 0 PMP-22/EMP/MP20/Claudin family Pox_LP_H2 PF03356.10 EGC39416.1 - 0.48 10.0 3.2 0.5 10.0 1.2 1.6 1 1 1 2 2 2 0 Viral late protein H2 DUF912 PF06024.7 EGC39416.1 - 0.53 10.3 6.6 1.4 9.0 4.5 1.9 1 1 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) DUF2116 PF09889.4 EGC39416.1 - 1.5 8.6 3.3 3.2 7.6 1.0 2.0 2 0 0 2 2 2 0 Uncharacterized protein containing a Zn-ribbon (DUF2116) 2TM PF13239.1 EGC39416.1 - 2.1 8.4 5.2 4.3 7.4 3.6 1.5 1 1 0 1 1 1 0 2TM domain GHMP_kinases_N PF00288.21 EGC39418.1 - 4.2e-14 52.3 1.8 1.6e-13 50.5 0.6 2.2 2 0 0 2 2 2 1 GHMP kinases N terminal domain GHMP_kinases_C PF08544.8 EGC39418.1 - 2.6e-06 27.5 0.0 1.9e-05 24.7 0.0 2.3 2 0 0 2 2 2 1 GHMP kinases C terminal WD40 PF00400.27 EGC39419.1 - 1.6e-37 126.0 16.1 3.5e-08 33.0 0.0 6.4 7 0 0 7 7 7 5 WD domain, G-beta repeat CAF1C_H4-bd PF12265.3 EGC39419.1 - 1.7e-27 95.1 1.0 5.3e-27 93.5 0.4 2.1 2 0 0 2 2 2 1 Histone-binding protein RBBP4 or subunit C of CAF1 complex eIF2A PF08662.6 EGC39419.1 - 0.00014 21.6 1.4 0.0029 17.3 0.1 2.7 3 0 0 3 3 3 1 Eukaryotic translation initiation factor eIF2A Cas1_AcylT PF07779.7 EGC39420.1 - 0.13 10.6 0.0 0.14 10.6 0.0 1.0 1 0 0 1 1 1 0 10 TM Acyl Transferase domain found in Cas1p FDX-ACB PF03147.9 EGC39420.1 - 0.14 12.3 0.1 0.31 11.2 0.0 1.5 1 1 0 1 1 1 0 Ferredoxin-fold anticodon binding domain FNIP PF05725.7 EGC39421.1 - 6.5e-12 45.2 29.2 3.3e-06 26.9 0.1 7.5 4 1 1 6 6 6 5 FNIP Repeat DUF3683 PF12447.3 EGC39421.1 - 0.029 14.2 1.2 0.077 12.8 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3683) Peptidase_C97 PF05903.9 EGC39422.1 - 2.8e-27 95.3 0.4 3.2e-27 95.1 0.2 1.0 1 0 0 1 1 1 1 PPPDE putative peptidase domain Cys_Met_Meta_PP PF01053.15 EGC39424.1 - 1.5e-155 517.2 0.0 1.7e-155 517.1 0.0 1.0 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Aminotran_1_2 PF00155.16 EGC39424.1 - 1.1e-07 31.1 0.0 1.6e-07 30.5 0.0 1.3 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGC39424.1 - 1.2e-06 27.7 0.2 5e-06 25.7 0.1 2.1 1 1 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Aminotran_5 PF00266.14 EGC39424.1 - 7.1e-06 25.0 0.0 1.1e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Aminotransferase class-V Met_gamma_lyase PF06838.6 EGC39424.1 - 0.00026 19.3 0.0 0.00045 18.6 0.0 1.3 1 0 0 1 1 1 1 Methionine gamma-lyase Beta_elim_lyase PF01212.16 EGC39424.1 - 0.068 12.2 0.1 0.18 10.9 0.1 1.9 1 1 0 1 1 1 0 Beta-eliminating lyase Las1 PF04031.8 EGC39424.1 - 0.083 12.5 0.0 0.17 11.5 0.0 1.4 1 0 0 1 1 1 0 Las1-like Mod_r PF07200.8 EGC39425.1 - 1e-16 61.1 18.5 1e-16 61.1 12.8 1.6 2 0 0 2 2 2 1 Modifier of rudimentary (Mod(r)) protein Phage_HK97_TLTM PF06120.6 EGC39425.1 - 0.027 13.8 0.5 0.05 12.9 0.4 1.5 1 0 0 1 1 1 0 Tail length tape measure protein Ndc1_Nup PF09531.5 EGC39425.1 - 0.32 9.3 12.7 0.44 8.9 8.8 1.2 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup Mitovir_RNA_pol PF05919.6 EGC39425.1 - 1.7 7.5 8.8 1 8.2 4.7 1.5 2 0 0 2 2 2 0 Mitovirus RNA-dependent RNA polymerase DUF2613 PF11021.3 EGC39426.1 - 0.031 13.9 0.2 0.043 13.5 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2613) PHO4 PF01384.15 EGC39426.1 - 0.081 11.5 0.0 0.081 11.5 0.0 1.0 1 0 0 1 1 1 0 Phosphate transporter family Sec1 PF00995.18 EGC39427.1 - 1.1e-82 278.5 27.0 1.2e-82 278.3 18.7 1.0 1 0 0 1 1 1 1 Sec1 family PIG-U PF06728.8 EGC39428.1 - 1.9e-116 389.0 45.0 2.4e-116 388.7 31.2 1.1 1 0 0 1 1 1 1 GPI transamidase subunit PIG-U Claudin_2 PF13903.1 EGC39428.1 - 8.9 5.9 15.6 1.6 8.3 1.3 3.2 2 2 0 3 3 3 0 PMP-22/EMP/MP20/Claudin tight junction UCH PF00443.24 EGC39431.1 - 1.2e-56 191.7 1.0 1.2e-56 191.7 0.7 3.4 3 0 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase USP7_ICP0_bdg PF12436.3 EGC39431.1 - 1.1e-55 188.6 3.3 1.4e-54 184.9 2.3 2.7 1 1 0 1 1 1 1 ICP0-binding domain of Ubiquitin-specific protease 7 USP7_C2 PF14533.1 EGC39431.1 - 4e-41 140.7 13.3 7.1e-29 100.7 0.1 4.2 3 1 1 4 4 4 2 Ubiquitin-specific protease C-terminal UCH_1 PF13423.1 EGC39431.1 - 1e-33 117.0 0.0 1e-33 117.0 0.0 3.3 3 1 1 4 4 4 1 Ubiquitin carboxyl-terminal hydrolase MATH PF00917.21 EGC39431.1 - 9.8e-14 51.6 0.0 9.8e-14 51.6 0.0 3.1 4 0 0 4 4 4 1 MATH domain Ubiquitin_2 PF14560.1 EGC39431.1 - 6.8e-05 23.0 0.5 0.015 15.5 0.0 3.3 3 0 0 3 3 3 1 Ubiquitin-like domain DUF702 PF05142.7 EGC39431.1 - 8.1 6.5 8.5 3.6 7.7 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF702) Ribosomal_L30_N PF08079.7 EGC39432.1 - 1.6e-21 76.0 4.4 2.5e-21 75.4 3.1 1.3 1 0 0 1 1 1 1 Ribosomal L30 N-terminal domain Ribosomal_L30 PF00327.15 EGC39432.1 - 2.5e-20 71.7 2.1 5.5e-20 70.6 0.9 2.1 3 0 0 3 3 3 1 Ribosomal protein L30p/L7e DnaJ PF00226.26 EGC39433.1 - 0.00082 19.0 0.0 0.0033 17.1 0.0 2.0 1 0 0 1 1 1 1 DnaJ domain zf-TRAF PF02176.13 EGC39434.1 - 4.4e-15 55.8 18.9 7.7e-12 45.4 5.8 4.2 3 1 1 4 4 4 2 TRAF-type zinc finger Sina PF03145.11 EGC39434.1 - 5.7e-06 26.1 21.5 0.0005 19.7 0.4 4.0 2 1 1 4 4 4 3 Seven in absentia protein family zf-C3HC4_2 PF13923.1 EGC39434.1 - 1.4e-05 25.0 8.7 1.4e-05 25.0 6.0 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC39434.1 - 0.00027 20.5 6.1 0.00027 20.5 4.2 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) SlyX PF04102.7 EGC39434.1 - 0.013 15.8 2.8 0.034 14.5 2.0 1.7 1 0 0 1 1 1 0 SlyX WEMBL PF05701.6 EGC39434.1 - 0.016 13.7 1.0 0.023 13.1 0.7 1.2 1 0 0 1 1 1 0 Weak chloroplast movement under blue light DUF1664 PF07889.7 EGC39434.1 - 0.21 11.4 2.6 0.41 10.4 1.8 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1664) zf-RING_2 PF13639.1 EGC39434.1 - 1 9.2 16.4 0.48 10.2 6.5 3.3 2 1 0 2 2 2 0 Ring finger domain HSP70 PF00012.15 EGC39435.1 - 3.3e-258 857.5 15.5 3.9e-258 857.3 10.7 1.0 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGC39435.1 - 6.9e-19 67.6 1.0 2.2e-17 62.6 0.2 2.2 2 0 0 2 2 2 1 MreB/Mbl protein DDR PF08841.5 EGC39435.1 - 0.001 17.9 0.2 0.047 12.5 0.1 2.3 2 0 0 2 2 2 1 Diol dehydratase reactivase ATPase-like domain Hydantoinase_A PF01968.13 EGC39435.1 - 0.0013 17.8 9.4 0.053 12.6 0.0 3.9 3 1 0 4 4 4 2 Hydantoinase/oxoprolinase FGGY_C PF02782.11 EGC39435.1 - 0.014 15.0 0.0 0.032 13.8 0.0 1.6 1 0 0 1 1 1 0 FGGY family of carbohydrate kinases, C-terminal domain DDE_Tnp_IS1 PF03400.8 EGC39435.1 - 0.14 12.2 0.0 1.6 8.8 0.0 2.3 2 0 0 2 2 2 0 IS1 transposase FtsA PF14450.1 EGC39435.1 - 0.15 11.8 12.0 1.7 8.4 0.1 4.6 3 1 0 3 3 3 0 Cell division protein FtsA Arif-1 PF06770.6 EGC39436.1 - 0.069 12.5 0.3 0.086 12.1 0.2 1.1 1 0 0 1 1 1 0 Actin-rearrangement-inducing factor (Arif-1) HCNGP PF07818.8 EGC39436.1 - 0.07 13.1 1.7 0.11 12.5 1.2 1.3 1 0 0 1 1 1 0 HCNGP-like protein Orai-1 PF07856.7 EGC39436.1 - 0.1 12.1 0.1 0.14 11.7 0.0 1.2 1 0 0 1 1 1 0 Mediator of CRAC channel activity DUF2254 PF10011.4 EGC39436.1 - 0.47 8.8 2.7 0.67 8.3 1.9 1.2 1 0 0 1 1 1 0 Predicted membrane protein (DUF2254) FixQ PF05545.6 EGC39436.1 - 0.61 9.7 3.4 4.3 7.0 0.1 2.3 2 0 0 2 2 2 0 Cbb3-type cytochrome oxidase component FixQ Glyco_hydro_25 PF01183.15 EGC39437.1 - 3.4e-08 33.5 3.1 4.3e-08 33.1 2.2 1.1 1 0 0 1 1 1 1 Glycosyl hydrolases family 25 zf-C4pol PF14260.1 EGC39437.1 - 0.0014 18.6 0.1 0.0034 17.3 0.1 1.6 1 0 0 1 1 1 1 C4-type zinc-finger of DNA polymerase delta Syntaxin PF00804.20 EGC39438.1 - 9.8e-08 32.0 2.3 9.8e-08 32.0 1.6 2.8 1 1 0 2 2 2 1 Syntaxin SNARE PF05739.14 EGC39438.1 - 3.8e-06 26.4 1.3 3.8e-06 26.4 0.9 2.5 1 1 1 2 2 2 1 SNARE domain MCPsignal PF00015.16 EGC39438.1 - 0.0055 16.2 1.2 0.0098 15.4 0.3 1.8 2 0 0 2 2 2 1 Methyl-accepting chemotaxis protein (MCP) signalling domain Rhabdo_M1 PF03342.8 EGC39438.1 - 0.018 14.1 0.4 0.031 13.4 0.3 1.5 1 1 0 1 1 1 0 Rhabdovirus M1 matrix protein (M1 polymerase-associated protein) MTS_N PF08468.6 EGC39438.1 - 0.033 14.0 0.2 0.088 12.6 0.1 1.8 1 1 0 1 1 1 0 Methyltransferase small domain N-terminal Syntaxin_2 PF14523.1 EGC39438.1 - 0.042 13.8 12.5 0.093 12.7 3.9 2.6 2 1 0 2 2 2 0 Syntaxin-like protein DUF948 PF06103.6 EGC39438.1 - 0.059 13.2 4.9 5.6 6.9 0.1 3.2 2 2 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Med9 PF07544.8 EGC39438.1 - 0.11 12.2 1.2 5.6 6.7 0.1 2.8 2 0 0 2 2 2 0 RNA polymerase II transcription mediator complex subunit 9 Reo_sigmaC PF04582.7 EGC39438.1 - 0.14 11.2 4.9 0.074 12.2 0.4 2.0 2 0 0 2 2 2 0 Reovirus sigma C capsid protein Asn_synthase PF00733.16 EGC39439.1 - 1.1e-56 192.1 0.0 1.4e-56 191.8 0.0 1.1 1 0 0 1 1 1 1 Asparagine synthase GATase_7 PF13537.1 EGC39439.1 - 7e-42 142.0 0.0 1.5e-41 141.0 0.0 1.6 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_6 PF13522.1 EGC39439.1 - 1.3e-35 122.2 0.0 1.9e-35 121.7 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_2 PF00310.16 EGC39439.1 - 3.6e-06 25.9 0.0 0.13 10.9 0.0 3.1 1 1 2 3 3 3 3 Glutamine amidotransferases class-II DUF3700 PF12481.3 EGC39439.1 - 5e-05 22.6 0.0 9.8e-05 21.6 0.0 1.4 1 0 0 1 1 1 1 Aluminium induced protein Utp21 PF04192.7 EGC39440.1 - 1.3e-43 148.8 0.7 3.1e-43 147.6 0.5 1.6 1 1 0 1 1 1 1 Utp21 specific WD40 associated putative domain WD40 PF00400.27 EGC39440.1 - 8.7e-21 72.9 6.1 0.0018 18.1 0.0 8.8 8 0 0 8 8 8 7 WD domain, G-beta repeat E1_DerP2_DerF2 PF02221.10 EGC39441.1 - 0.012 15.8 0.1 0.015 15.5 0.0 1.1 1 0 0 1 1 1 0 ML domain Peptidase_C14 PF00656.17 EGC39442.1 - 1.9e-07 31.0 0.5 4e-07 29.9 0.2 1.5 1 1 0 1 1 1 1 Caspase domain DivIC PF04977.10 EGC39442.1 - 0.063 12.7 1.8 1.1 8.7 0.5 2.8 2 0 0 2 2 2 0 Septum formation initiator Bap31 PF05529.7 EGC39442.1 - 0.095 12.1 2.2 0.78 9.1 0.5 2.5 2 0 0 2 2 2 0 B-cell receptor-associated protein 31-like FG-GAP PF01839.18 EGC39443.1 - 4.6e-19 67.5 10.9 0.00021 20.8 0.1 4.8 4 0 0 4 4 4 4 FG-GAP repeat Zn_dep_PLPC PF00882.13 EGC39443.1 - 7.9e-16 58.1 0.4 1.6e-15 57.1 0.3 1.5 1 0 0 1 1 1 1 Zinc dependent phospholipase C VCBS PF13517.1 EGC39443.1 - 7e-11 42.3 17.9 1.2e-05 25.5 2.4 4.8 4 1 1 5 5 5 4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella TcdB_toxin_midN PF12256.3 EGC39443.1 - 2.3e-05 23.9 1.2 0.9 8.9 0.0 4.0 4 0 0 4 4 4 2 Insecticide toxin TcdB middle/N-terminal region YrhK PF14145.1 EGC39443.1 - 0.037 13.6 0.5 0.14 11.8 0.1 2.2 2 0 0 2 2 2 0 YrhK-like protein EF-hand_1 PF00036.27 EGC39443.1 - 0.12 11.7 0.7 5.6 6.5 0.0 3.2 2 0 0 2 2 2 0 EF hand DUF3329 PF11808.3 EGC39445.1 - 6.3 6.9 5.9 6.2 6.9 0.5 3.0 3 1 1 4 4 4 0 Domain of unknown function (DUF3329) EGF_2 PF07974.8 EGC39446.1 - 0.014 15.5 11.6 0.045 13.9 8.1 1.9 1 0 0 1 1 1 0 EGF-like domain H_lectin PF09458.5 EGC39447.1 - 1.8e-19 69.1 0.9 1.8e-19 69.1 0.6 2.1 2 0 0 2 2 2 1 H-type lectin domain Fascin PF06268.8 EGC39447.1 - 1.3e-06 28.4 0.5 2.1e-06 27.7 0.4 1.3 1 0 0 1 1 1 1 Fascin domain RicinB_lectin_2 PF14200.1 EGC39447.1 - 0.00015 22.0 19.4 0.00031 21.0 0.2 3.3 1 1 1 3 3 3 2 Ricin-type beta-trefoil lectin domain-like FGF PF00167.13 EGC39447.1 - 0.00042 20.0 3.1 0.00088 19.0 0.1 2.6 1 1 1 2 2 2 1 Fibroblast growth factor Inhibitor_I42 PF09394.5 EGC39447.1 - 0.05 13.9 0.6 1.7 9.0 0.0 2.9 1 1 1 2 2 2 0 Chagasin family peptidase inhibitor I42 Neur_chan_memb PF02932.11 EGC39447.1 - 0.99 9.2 7.5 1.3 8.8 5.2 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region EGF_2 PF07974.8 EGC39448.1 - 0.28 11.3 16.0 0.039 14.1 8.1 1.9 2 0 0 2 2 2 0 EGF-like domain MORN PF02493.15 EGC39449.1 - 9.7e-26 87.9 51.0 0.00014 21.3 0.2 12.3 12 0 0 12 12 12 10 MORN repeat SM-ATX PF14438.1 EGC39449.1 - 1.1 9.1 5.7 4.1 7.4 0.0 3.7 4 0 0 4 4 4 0 Ataxin 2 SM domain Adeno_E3_CR2 PF02439.10 EGC39451.1 - 0.047 13.2 3.3 0.085 12.4 2.3 1.4 1 0 0 1 1 1 0 Adenovirus E3 region protein CR2 NSP2-B_epitope PF14757.1 EGC39451.1 - 0.082 12.3 0.4 0.12 11.8 0.3 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Vpu PF00558.14 EGC39451.1 - 0.11 12.0 0.7 0.19 11.3 0.5 1.4 1 0 0 1 1 1 0 Vpu protein Plasmod_dom_1 PF09715.5 EGC39451.1 - 0.22 11.4 4.2 0.13 12.1 1.0 2.0 2 0 0 2 2 2 0 Plasmodium protein of unknown function (Plasmod_dom_1) FixQ PF05545.6 EGC39451.1 - 0.59 9.8 2.0 2.2 7.9 1.4 1.9 1 1 0 1 1 1 0 Cbb3-type cytochrome oxidase component FixQ SieB PF14163.1 EGC39452.1 - 0.022 14.3 0.2 0.033 13.7 0.1 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B NSP2-B_epitope PF14757.1 EGC39452.1 - 0.073 12.5 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein Vpu PF00558.14 EGC39452.1 - 0.13 11.8 0.5 0.22 11.0 0.4 1.4 1 0 0 1 1 1 0 Vpu protein SieB PF14163.1 EGC39454.1 - 0.023 14.2 0.2 0.036 13.6 0.2 1.3 1 0 0 1 1 1 0 Superinfection exclusion protein B NSP2-B_epitope PF14757.1 EGC39454.1 - 0.073 12.5 0.3 0.11 11.9 0.2 1.2 1 0 0 1 1 1 0 Immunogenic region of nsp2 protein of arterivirus polyprotein EGF_2 PF07974.8 EGC39455.1 - 0.025 14.7 11.7 0.067 13.3 8.1 1.8 1 0 0 1 1 1 0 EGF-like domain EGF_2 PF07974.8 EGC39456.1 - 0.021 15.0 11.6 0.052 13.7 8.1 1.7 1 0 0 1 1 1 0 EGF-like domain LRR_4 PF12799.2 EGC39457.1 - 5.2e-13 48.2 42.7 0.00016 21.1 0.8 9.6 8 3 2 10 10 10 5 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC39457.1 - 1.1e-10 40.3 51.6 0.01 15.8 0.1 13.3 14 0 0 14 14 14 7 Leucine Rich repeat LRR_7 PF13504.1 EGC39457.1 - 1.2e-08 33.7 18.9 1.2 9.6 0.0 11.7 11 1 0 11 11 11 1 Leucine rich repeat LRR_1 PF00560.28 EGC39457.1 - 2.8e-07 29.6 35.6 2.9 8.2 0.6 13.0 13 1 0 13 13 13 4 Leucine Rich Repeat LRR_8 PF13855.1 EGC39457.1 - 1.1e-06 28.2 35.1 0.0017 18.1 4.0 8.8 5 3 5 10 10 10 4 Leucine rich repeat DUF4217 PF13959.1 EGC39457.1 - 0.11 12.0 0.0 0.32 10.5 0.0 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4217) AA_permease_2 PF13520.1 EGC39458.1 - 1e-31 109.9 52.9 1.2e-31 109.6 36.7 1.1 1 0 0 1 1 1 1 Amino acid permease AA_permease PF00324.16 EGC39458.1 - 2.4e-25 88.8 48.5 5.9e-25 87.5 33.6 1.5 1 1 0 1 1 1 1 Amino acid permease RNA_pol_Rpb1_5 PF04998.12 EGC39460.1 - 1.6e-96 322.7 2.3 1.6e-96 322.7 1.6 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 5 RNA_pol_Rpb1_1 PF04997.7 EGC39460.1 - 4.4e-93 312.2 4.1 4.4e-93 312.2 2.9 1.7 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 1 RNA_pol_Rpb1_2 PF00623.15 EGC39460.1 - 1.3e-69 233.4 0.2 9.8e-69 230.5 0.0 2.5 2 0 0 2 2 2 1 RNA polymerase Rpb1, domain 2 RNA_pol_Rpb1_3 PF04983.13 EGC39460.1 - 1.3e-36 125.6 0.1 1.7e-35 122.0 0.0 2.9 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 3 RNA_pol_Rpb1_4 PF05000.12 EGC39460.1 - 5.7e-31 106.4 2.0 3.5e-30 103.9 0.1 3.2 3 0 0 3 3 3 1 RNA polymerase Rpb1, domain 4 EGF_2 PF07974.8 EGC39461.1 - 0.03 14.4 6.0 0.03 14.4 4.2 2.6 3 0 0 3 3 3 0 EGF-like domain hEGF PF12661.2 EGC39461.1 - 0.094 12.8 2.0 0.41 10.8 1.4 2.2 1 0 0 1 1 1 0 Human growth factor-like EGF cEGF PF12662.2 EGC39461.1 - 3.6 7.3 10.5 0.45 10.2 2.8 2.8 3 0 0 3 3 3 0 Complement Clr-like EGF-like Voltage_CLC PF00654.15 EGC39462.1 - 1.5e-94 316.9 25.6 2e-94 316.5 15.0 2.0 1 1 1 2 2 2 2 Voltage gated chloride channel CBS PF00571.23 EGC39462.1 - 1.7e-09 37.2 5.2 1.6e-06 27.7 0.0 3.2 4 0 0 4 4 4 2 CBS domain TAT_signal PF10518.4 EGC39462.1 - 0.33 11.0 0.1 0.33 11.0 0.1 2.3 2 0 0 2 2 2 0 TAT (twin-arginine translocation) pathway signal sequence Elong_Iki1 PF10483.4 EGC39463.1 - 5.8e-19 68.5 4.4 3.5e-18 65.9 3.0 2.1 1 1 0 1 1 1 1 Elongator subunit Iki1 FNIP PF05725.7 EGC39464.1 - 0.00016 21.5 16.7 0.015 15.2 2.5 4.7 3 2 1 4 4 4 2 FNIP Repeat HeH PF12949.2 EGC39464.1 - 0.0017 17.8 2.3 0.0036 16.8 1.6 1.6 1 0 0 1 1 1 1 HeH/LEM domain SAP PF02037.22 EGC39464.1 - 0.0075 15.7 2.6 0.0075 15.7 1.8 2.6 4 0 0 4 4 4 1 SAP domain SseC PF04888.7 EGC39464.1 - 5.6 6.1 8.9 47 3.1 0.0 2.1 2 0 0 2 2 2 0 Secretion system effector C (SseC) like family PseudoU_synth_2 PF00849.17 EGC39465.1 - 1.4e-15 57.5 0.6 5.3e-15 55.6 0.0 2.3 2 1 0 2 2 2 1 RNA pseudouridylate synthase S4 PF01479.20 EGC39465.1 - 5.8e-12 44.8 1.7 1.4e-10 40.3 0.1 2.7 2 0 0 2 2 2 1 S4 domain DUF892 PF05974.7 EGC39465.1 - 0.068 12.9 0.1 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF892) TMEMspv1-c74-12 PF11044.3 EGC39465.1 - 0.37 10.3 4.8 1.4 8.5 3.4 2.0 1 0 0 1 1 1 0 Plectrovirus spv1-c74 ORF 12 transmembrane protein ketoacyl-synt PF00109.21 EGC39468.1 - 4e-67 226.3 0.0 5.7e-67 225.8 0.0 1.2 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC39468.1 - 3.2e-44 151.5 0.0 5.7e-44 150.7 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC39468.1 - 8.6e-34 115.9 0.0 1.7e-33 114.9 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain Methyltransf_12 PF08242.7 EGC39468.1 - 9.5e-23 80.5 0.0 9.5e-23 80.5 0.0 3.3 4 0 0 4 4 3 1 Methyltransferase domain KR PF08659.5 EGC39468.1 - 2.3e-22 79.5 0.0 3.7e-22 78.8 0.0 1.3 1 0 0 1 1 1 1 KR domain PS-DH PF14765.1 EGC39468.1 - 2.7e-22 79.2 0.0 4.1e-22 78.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC39468.1 - 5.1e-13 49.2 0.0 8.5e-13 48.5 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_23 PF13489.1 EGC39468.1 - 3.2e-11 43.2 0.0 8.2e-11 41.8 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain ADH_zinc_N_2 PF13602.1 EGC39468.1 - 5.4e-06 27.3 0.0 1.1e-05 26.3 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Thiolase_N PF00108.18 EGC39468.1 - 6.6e-06 25.2 0.6 1.8e-05 23.8 0.1 1.8 2 0 0 2 2 2 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC39468.1 - 0.00023 21.6 0.0 0.00078 20.0 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39468.1 - 0.00029 21.2 0.0 0.001 19.5 0.0 2.0 1 0 0 1 1 1 1 Methyltransferase domain Abhydrolase_5 PF12695.2 EGC39468.1 - 0.18 11.5 0.0 0.36 10.5 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family LktC PF06261.6 EGC39469.1 - 0.017 14.8 0.1 0.026 14.2 0.1 1.3 1 0 0 1 1 1 0 Actinobacillus actinomycetemcomitans leukotoxin activator LktC AAA PF00004.24 EGC39470.1 - 2.5e-41 140.9 0.0 4.8e-41 140.0 0.0 1.5 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC39470.1 - 9e-06 25.4 0.0 5.3e-05 22.9 0.0 2.3 2 1 0 2 2 2 1 AAA domain (dynein-related subfamily) AAA_22 PF13401.1 EGC39470.1 - 1.7e-05 24.9 0.0 0.0013 18.8 0.0 2.4 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGC39470.1 - 0.00022 21.2 0.0 0.00098 19.0 0.0 2.0 2 0 0 2 2 2 1 AAA domain (Cdc48 subfamily) AAA_16 PF13191.1 EGC39470.1 - 0.00066 19.7 0.0 0.0012 18.9 0.0 1.5 1 1 0 1 1 1 1 AAA ATPase domain DUF815 PF05673.8 EGC39470.1 - 0.0013 17.7 0.0 0.0023 16.9 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_33 PF13671.1 EGC39470.1 - 0.0024 17.7 0.0 0.0043 16.9 0.0 1.4 1 0 0 1 1 1 1 AAA domain RNA_helicase PF00910.17 EGC39470.1 - 0.003 17.7 0.0 0.0073 16.4 0.0 1.7 1 0 0 1 1 1 1 RNA helicase AAA_17 PF13207.1 EGC39470.1 - 0.0053 17.5 0.0 0.011 16.5 0.0 1.7 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC39470.1 - 0.0054 15.8 0.0 0.012 14.6 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin RuvB_N PF05496.7 EGC39470.1 - 0.0062 15.6 0.0 0.013 14.5 0.0 1.4 1 0 0 1 1 1 1 Holliday junction DNA helicase ruvB N-terminus AAA_19 PF13245.1 EGC39470.1 - 0.012 15.3 0.1 0.024 14.4 0.0 1.4 1 0 0 1 1 1 0 Part of AAA domain AAA_28 PF13521.1 EGC39470.1 - 0.018 14.9 0.0 0.028 14.4 0.0 1.2 1 0 0 1 1 1 0 AAA domain Mg_chelatase PF01078.16 EGC39470.1 - 0.025 13.7 0.0 0.052 12.7 0.0 1.4 1 0 0 1 1 1 0 Magnesium chelatase, subunit ChlI TIP49 PF06068.8 EGC39470.1 - 0.029 13.0 0.0 0.051 12.2 0.0 1.3 1 0 0 1 1 1 0 TIP49 C-terminus AAA_3 PF07726.6 EGC39470.1 - 0.035 13.6 0.0 0.068 12.7 0.0 1.4 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) Sigma54_activ_2 PF14532.1 EGC39470.1 - 0.05 13.6 0.0 0.11 12.5 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain IstB_IS21 PF01695.12 EGC39470.1 - 0.06 12.7 0.0 0.1 11.9 0.0 1.3 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EGC39470.1 - 0.079 12.4 0.0 0.18 11.2 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain AAA_24 PF13479.1 EGC39470.1 - 0.09 12.3 0.0 0.17 11.4 0.0 1.4 1 0 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC39470.1 - 0.11 12.1 0.0 14 5.2 0.0 2.4 1 1 1 2 2 2 0 Archaeal ATPase AAA_14 PF13173.1 EGC39470.1 - 0.14 12.0 0.0 0.26 11.1 0.0 1.4 1 0 0 1 1 1 0 AAA domain RNase_Zc3h12a PF11977.3 EGC39471.1 - 6.2e-27 94.3 0.1 1.4e-26 93.1 0.1 1.6 1 0 0 1 1 1 1 Zc3h12a-like Ribonuclease NYN domain Atrophin-1 PF03154.10 EGC39471.1 - 2.7 6.0 54.9 0.037 12.1 0.3 2.4 2 0 0 2 2 2 0 Atrophin-1 family FNIP PF05725.7 EGC39472.1 - 2.2e-50 168.3 70.4 1.3e-12 47.3 1.8 12.7 11 2 2 13 13 13 8 FNIP Repeat Pkinase PF00069.20 EGC39472.1 - 6.4e-31 107.4 4.7 7.9e-28 97.3 1.1 3.1 2 1 0 2 2 2 2 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39472.1 - 1.2e-13 50.7 0.3 2.7e-13 49.5 0.1 1.6 2 0 0 2 2 2 1 Protein tyrosine kinase MATH PF00917.21 EGC39472.1 - 1.1e-10 41.8 11.4 2.5e-05 24.4 0.0 3.6 3 0 0 3 3 3 2 MATH domain Kinase-like PF14531.1 EGC39472.1 - 0.0021 17.0 0.1 0.0068 15.4 0.0 1.8 2 0 0 2 2 2 1 Kinase-like APH PF01636.18 EGC39472.1 - 0.0042 16.8 0.0 0.0066 16.2 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family DUF1769 PF08588.5 EGC39472.1 - 0.032 14.1 12.0 9.2 6.2 0.1 6.2 3 1 2 6 6 6 0 Protein of unknown function (DUF1769) Kdo PF06293.9 EGC39472.1 - 0.041 12.9 0.0 0.082 11.9 0.0 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family MIT PF04212.13 EGC39473.1 - 4.7e-19 68.0 2.3 8e-19 67.2 1.6 1.4 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain FeoC PF09012.5 EGC39473.1 - 0.084 12.5 0.1 0.18 11.5 0.0 1.5 1 0 0 1 1 1 0 FeoC like transcriptional regulator HutP PF09021.6 EGC39473.1 - 0.14 12.3 0.0 0.25 11.5 0.0 1.4 1 0 0 1 1 1 0 HutP Inositol_P PF00459.20 EGC39474.1 - 1.3e-40 139.4 0.0 1.6e-40 139.1 0.0 1.0 1 0 0 1 1 1 1 Inositol monophosphatase family tRNA-synt_2b PF00587.20 EGC39475.1 - 2.3e-36 124.9 0.1 4.5e-36 124.0 0.1 1.5 1 0 0 1 1 1 1 tRNA synthetase class II core domain (G, H, P, S and T) HGTP_anticodon PF03129.15 EGC39475.1 - 0.00022 21.1 0.2 0.0007 19.4 0.1 1.9 1 0 0 1 1 1 1 Anticodon binding domain DUF1319 PF07028.6 EGC39475.1 - 9 6.5 8.8 0.29 11.3 0.6 2.5 3 0 0 3 3 3 0 Protein of unknown function (DUF1319) DUF4131 PF13567.1 EGC39476.1 - 0.022 14.1 0.4 0.041 13.2 0.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4131) CBM_14 PF01607.19 EGC39477.1 - 7e-08 32.2 5.9 1.2e-07 31.5 4.1 1.3 1 0 0 1 1 1 1 Chitin binding Peritrophin-A domain Ras PF00071.17 EGC39478.1 - 2.5e-46 156.9 0.3 2.9e-46 156.8 0.2 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39478.1 - 6.9e-16 58.8 0.1 9.2e-16 58.4 0.1 1.2 1 0 0 1 1 1 1 Miro-like protein GTP_EFTU PF00009.22 EGC39478.1 - 4.8e-11 42.4 1.0 4.4e-08 32.7 0.1 2.1 1 1 1 2 2 2 2 Elongation factor Tu GTP binding domain Arf PF00025.16 EGC39478.1 - 6e-10 38.6 0.0 7e-10 38.4 0.0 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC39478.1 - 0.00021 21.2 0.1 0.00034 20.5 0.1 1.3 1 1 0 1 1 1 1 50S ribosome-binding GTPase G-alpha PF00503.15 EGC39478.1 - 0.00089 18.0 0.0 0.0011 17.8 0.0 1.1 1 0 0 1 1 1 1 G-protein alpha subunit AAA_14 PF13173.1 EGC39478.1 - 0.0079 16.0 0.0 0.012 15.4 0.0 1.5 1 0 0 1 1 1 1 AAA domain SRPRB PF09439.5 EGC39478.1 - 0.021 14.0 0.1 0.023 13.9 0.1 1.1 1 0 0 1 1 1 0 Signal recognition particle receptor beta subunit Peptidase_M28 PF04389.12 EGC39479.1 - 4.6e-10 39.5 0.0 2e-09 37.4 0.0 2.0 2 0 0 2 2 2 1 Peptidase family M28 Nicastrin PF05450.10 EGC39479.1 - 0.0047 16.1 1.6 0.01 15.0 0.0 2.1 2 0 0 2 2 2 1 Nicastrin Sugarporin_N PF11471.3 EGC39480.1 - 0.0067 16.0 0.4 0.012 15.2 0.3 1.4 1 0 0 1 1 1 1 Maltoporin periplasmic N-terminal extension DUF2951 PF11166.3 EGC39480.1 - 0.0072 16.1 3.1 0.0083 15.9 0.2 2.3 2 1 1 3 3 3 1 Protein of unknown function (DUF2951) Init_tRNA_PT PF04179.7 EGC39480.1 - 0.0087 14.9 3.5 0.0092 14.8 2.4 1.0 1 0 0 1 1 1 1 Initiator tRNA phosphoribosyl transferase Prefoldin_2 PF01920.15 EGC39481.1 - 0.041 13.6 2.0 5.5 6.8 0.7 2.4 2 0 0 2 2 2 0 Prefoldin subunit Endotoxin_N PF03945.9 EGC39482.1 - 0.00049 19.5 0.0 0.16 11.3 0.0 2.3 2 0 0 2 2 2 2 delta endotoxin, N-terminal domain DUF4220 PF13968.1 EGC39483.1 - 0.069 12.2 5.2 0.12 11.3 3.5 1.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4220) Gag_spuma PF03276.9 EGC39483.1 - 0.25 9.6 8.9 0.29 9.4 6.2 1.0 1 0 0 1 1 1 0 Spumavirus gag protein Menin PF05053.8 EGC39483.1 - 0.29 9.2 12.1 0.35 8.9 8.4 1.2 1 0 0 1 1 1 0 Menin NST1 PF13945.1 EGC39483.1 - 0.29 11.1 19.0 0.38 10.8 13.2 1.1 1 0 0 1 1 1 0 Salt tolerance down-regulator DUF2457 PF10446.4 EGC39483.1 - 0.6 8.7 14.7 0.71 8.5 10.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) Tetraspannin PF00335.15 EGC39483.1 - 0.61 9.3 4.1 0.7 9.1 2.8 1.2 1 0 0 1 1 1 0 Tetraspanin family Bul1_N PF04425.7 EGC39483.1 - 0.63 8.5 18.6 0.75 8.2 12.9 1.0 1 0 0 1 1 1 0 Bul1 N terminus Nop25 PF09805.4 EGC39483.1 - 0.73 9.9 15.9 0.92 9.5 11.0 1.1 1 0 0 1 1 1 0 Nucleolar protein 12 (25kDa) DUF1390 PF07150.6 EGC39483.1 - 1.5 8.1 21.4 2 7.7 14.8 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1390) Zip PF02535.17 EGC39483.1 - 1.8 7.5 3.4 2 7.3 2.4 1.1 1 0 0 1 1 1 0 ZIP Zinc transporter NPR3 PF03666.8 EGC39483.1 - 5.6 5.3 15.2 6.9 5.0 10.5 1.1 1 0 0 1 1 1 0 Nitrogen Permease regulator of amino acid transport activity 3 DUF3807 PF12720.2 EGC39483.1 - 6.7 6.8 16.0 9 6.4 11.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3807) RP-C_C PF11800.3 EGC39483.1 - 7.2 6.2 9.3 9.8 5.8 6.4 1.3 1 0 0 1 1 1 0 Replication protein C C-terminal region Erf4 PF10256.4 EGC39484.1 - 1.3e-06 28.2 8.1 0.00017 21.4 5.6 2.2 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Claudin_2 PF13903.1 EGC39484.1 - 0.012 15.2 0.1 0.012 15.2 0.1 1.7 2 0 0 2 2 2 0 PMP-22/EMP/MP20/Claudin tight junction SUR7 PF06687.7 EGC39484.1 - 0.018 14.6 3.5 0.026 14.1 2.4 1.3 1 0 0 1 1 1 0 SUR7/PalI family DUF4131 PF13567.1 EGC39484.1 - 0.058 12.8 1.0 0.1 12.0 0.7 1.3 1 1 0 1 1 1 0 Domain of unknown function (DUF4131) Pox_A14 PF05767.7 EGC39484.1 - 0.075 12.9 7.4 1.6 8.7 5.1 2.2 1 1 0 1 1 1 0 Poxvirus virion envelope protein A14 AsiA PF09010.5 EGC39484.1 - 0.21 11.4 1.6 0.34 10.8 0.1 2.0 2 0 0 2 2 2 0 Anti-Sigma Factor A Ninjurin PF04923.7 EGC39484.1 - 0.37 10.5 4.1 0.78 9.4 2.8 1.6 1 0 0 1 1 1 0 Ninjurin NfeD PF01957.13 EGC39484.1 - 1.9 8.5 6.4 21 5.2 4.7 2.0 1 1 1 2 2 2 0 NfeD-like C-terminal, partner-binding DUF4234 PF14018.1 EGC39484.1 - 9.9 5.9 8.6 3.9 7.2 0.2 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF4234) PCNA_C PF02747.10 EGC39485.1 - 1.3e-05 25.1 0.5 1.8e-05 24.6 0.3 1.2 1 0 0 1 1 1 1 Proliferating cell nuclear antigen, C-terminal domain OpcA PF07239.6 EGC39485.1 - 0.048 12.5 0.3 0.075 11.9 0.2 1.3 1 1 0 1 1 1 0 Outer membrane protein OpcA PI-PLC-X PF00388.14 EGC39488.1 - 1.8e-56 189.6 0.0 4.2e-56 188.4 0.0 1.7 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain PI-PLC-Y PF00387.14 EGC39488.1 - 1.2e-34 118.7 0.0 3.5e-34 117.3 0.0 1.8 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, Y domain C2 PF00168.25 EGC39488.1 - 6.1e-17 61.2 0.0 2.2e-16 59.4 0.0 2.0 2 0 0 2 2 2 1 C2 domain EF-hand_like PF09279.6 EGC39488.1 - 7.1e-10 38.7 0.1 1.8e-09 37.4 0.1 1.8 1 0 0 1 1 1 1 Phosphoinositide-specific phospholipase C, efhand-like EF-hand_8 PF13833.1 EGC39488.1 - 0.0074 15.8 0.5 0.0074 15.8 0.4 2.6 3 0 0 3 3 3 1 EF-hand domain pair EF-hand_7 PF13499.1 EGC39488.1 - 0.021 14.9 2.1 0.041 14.0 0.3 2.4 2 0 0 2 2 2 0 EF-hand domain pair COPI_assoc PF08507.5 EGC39489.1 - 1.4e-05 24.7 2.4 1.9e-05 24.3 1.6 1.1 1 0 0 1 1 1 1 COPI associated protein Cytochrom_B558a PF05038.8 EGC39489.1 - 0.0015 18.2 4.6 0.11 12.1 0.1 2.1 1 1 1 2 2 2 2 Cytochrome Cytochrome b558 alpha-subunit DUF3188 PF11384.3 EGC39489.1 - 0.071 12.6 0.8 0.16 11.5 0.5 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3188) Bacteriocin_IId PF09221.5 EGC39489.1 - 0.22 11.4 0.1 0.22 11.4 0.1 2.4 2 1 0 2 2 2 0 Bacteriocin class IId cyclical uberolysin-like Orthoreo_P10 PF07204.6 EGC39489.1 - 0.76 9.5 2.7 0.97 9.2 1.2 1.7 1 1 0 1 1 1 0 Orthoreovirus membrane fusion protein p10 AAA_17 PF13207.1 EGC39490.1 - 0.00015 22.5 0.0 0.00042 21.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain AAA_14 PF13173.1 EGC39490.1 - 0.036 13.9 2.3 0.062 13.2 0.0 2.5 2 1 0 2 2 2 0 AAA domain AAA_16 PF13191.1 EGC39490.1 - 0.13 12.2 0.0 0.9 9.4 0.0 2.2 2 0 0 2 2 2 0 AAA ATPase domain AAA_18 PF13238.1 EGC39490.1 - 0.22 11.8 2.5 2.3 8.5 1.6 2.9 1 1 1 2 2 2 0 AAA domain Patatin PF01734.17 EGC39491.1 - 1.6e-14 54.3 0.5 2.9e-13 50.1 0.3 2.5 1 1 0 1 1 1 1 Patatin-like phospholipase PH_11 PF15413.1 EGC39491.1 - 5.4e-05 23.4 5.1 0.00012 22.2 3.5 1.6 1 0 0 1 1 1 1 Pleckstrin homology domain PH PF00169.24 EGC39491.1 - 0.013 15.7 7.3 0.013 15.6 3.6 2.1 2 0 0 2 2 2 0 PH domain zf-CCHH PF10283.4 EGC39492.1 - 1.5e-12 47.0 1.0 2.9e-12 46.2 0.7 1.5 1 0 0 1 1 1 1 Zinc-finger (CX5CX6HX5H) motif FHA PF00498.21 EGC39492.1 - 0.35 11.0 4.1 0.44 10.7 0.1 2.6 2 0 0 2 2 2 0 FHA domain SprA-related PF12118.3 EGC39492.1 - 3.3 6.9 32.0 5.8 6.1 22.2 1.4 1 0 0 1 1 1 0 SprA-related family HAD_2 PF13419.1 EGC39493.1 - 4.4e-26 92.1 0.0 5.3e-26 91.8 0.0 1.1 1 0 0 1 1 1 1 Haloacid dehalogenase-like hydrolase Hydrolase_like PF13242.1 EGC39493.1 - 0.00018 21.1 0.1 0.0003 20.4 0.0 1.3 1 0 0 1 1 1 1 HAD-hyrolase-like Acid_PPase PF12689.2 EGC39493.1 - 0.01 15.4 0.1 1.6 8.3 0.0 2.2 2 0 0 2 2 2 0 Acid Phosphatase LRR_6 PF13516.1 EGC39494.1 - 7.6e-40 130.4 83.3 4.4e-06 26.2 0.2 18.7 18 0 0 18 18 18 14 Leucine Rich repeat LRR_1 PF00560.28 EGC39494.1 - 1.8e-08 33.2 58.1 1.9 8.8 0.0 16.1 17 0 0 17 17 17 8 Leucine Rich Repeat LRR_4 PF12799.2 EGC39494.1 - 1.9e-07 30.5 101.7 0.00025 20.5 1.6 11.8 6 3 8 14 14 14 11 Leucine Rich repeats (2 copies) LRR_7 PF13504.1 EGC39494.1 - 0.0075 16.2 40.4 8.2 7.1 0.0 13.5 13 1 0 13 13 13 3 Leucine rich repeat Lep_receptor_Ig PF06328.6 EGC39495.1 - 0.014 15.2 0.1 0.017 14.9 0.0 1.2 1 0 0 1 1 1 0 Ig-like C2-type domain HSP70 PF00012.15 EGC39496.1 - 3.1e-250 831.2 8.1 3.8e-250 830.9 5.6 1.1 1 0 0 1 1 1 1 Hsp70 protein MreB_Mbl PF06723.8 EGC39496.1 - 1.4e-16 60.0 1.4 2.5e-13 49.3 0.2 2.3 2 0 0 2 2 2 2 MreB/Mbl protein FGGY_C PF02782.11 EGC39496.1 - 0.0008 19.0 0.0 0.0055 16.3 0.0 2.3 2 0 0 2 2 2 1 FGGY family of carbohydrate kinases, C-terminal domain Hydantoinase_A PF01968.13 EGC39496.1 - 0.041 12.9 2.0 0.65 9.0 0.1 3.0 3 1 0 3 3 3 0 Hydantoinase/oxoprolinase cwf21 PF08312.7 EGC39496.1 - 0.088 12.6 1.1 2.3 8.1 0.1 2.6 2 0 0 2 2 2 0 cwf21 domain FtsA PF14450.1 EGC39496.1 - 0.1 12.4 11.6 4 7.2 0.0 4.7 5 0 0 5 5 5 0 Cell division protein FtsA FNIP PF05725.7 EGC39497.1 - 7.5e-39 131.4 47.8 2.9e-07 30.3 0.5 9.1 4 2 5 10 10 10 10 FNIP Repeat RhoGEF PF00621.15 EGC39499.1 - 9.2e-52 175.5 6.2 9.2e-52 175.5 4.3 2.4 2 0 0 2 2 2 1 RhoGEF domain VHP PF02209.14 EGC39499.1 - 1.9e-12 46.6 4.9 4.6e-12 45.4 3.4 1.7 1 0 0 1 1 1 1 Villin headpiece domain CH PF00307.26 EGC39499.1 - 2.6e-09 37.0 5.4 4.2e-09 36.4 0.0 3.7 4 0 0 4 4 4 1 Calponin homology (CH) domain CDC24 PF06395.6 EGC39499.1 - 0.00064 19.7 1.0 0.0019 18.2 0.1 2.4 2 0 0 2 2 2 1 CDC24 Calponin IQ PF00612.22 EGC39499.1 - 0.15 11.8 0.0 0.3 10.8 0.0 1.6 1 0 0 1 1 1 0 IQ calmodulin-binding motif DZR PF12773.2 EGC39502.1 - 0.00033 20.4 10.2 0.00063 19.5 7.1 1.5 1 0 0 1 1 1 1 Double zinc ribbon RhoGEF PF00621.15 EGC39503.1 - 1.5e-42 145.5 5.4 1.5e-42 145.5 3.7 2.3 2 0 0 2 2 2 1 RhoGEF domain Cofilin_ADF PF00241.15 EGC39504.1 - 9.2e-20 70.8 0.0 1e-19 70.6 0.0 1.0 1 0 0 1 1 1 1 Cofilin/tropomyosin-type actin-binding protein FNIP PF05725.7 EGC39505.1 - 9.9e-19 67.0 61.0 8.5e-07 28.8 4.1 10.2 7 3 6 13 13 13 10 FNIP Repeat DDE_Tnp_4 PF13359.1 EGC39506.1 - 9.9e-17 60.9 0.0 1.7e-16 60.1 0.0 1.4 1 0 0 1 1 1 1 DDE superfamily endonuclease PH PF00169.24 EGC39507.1 - 3.7e-05 23.8 8.9 0.00071 19.7 6.2 2.3 1 1 0 1 1 1 1 PH domain Tmemb_9 PF05434.6 EGC39507.1 - 0.22 11.2 0.1 0.22 11.2 0.1 1.7 2 0 0 2 2 2 0 TMEM9 DUF4207 PF13904.1 EGC39507.1 - 1 8.6 9.2 0.13 11.5 0.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4207) FNIP PF05725.7 EGC39508.1 - 1.4e-09 37.7 2.1 1.5e-05 24.8 0.1 2.2 1 1 1 2 2 2 2 FNIP Repeat Ribosomal_S21e PF01249.13 EGC39508.1 - 9.4e-06 25.4 0.0 1.2e-05 25.1 0.0 1.3 1 0 0 1 1 1 1 Ribosomal protein S21e Peptidase_M28 PF04389.12 EGC39509.1 - 1.6e-31 109.4 0.0 2.3e-31 108.9 0.0 1.2 1 0 0 1 1 1 1 Peptidase family M28 Nicastrin PF05450.10 EGC39509.1 - 0.0074 15.5 0.0 0.014 14.6 0.0 1.4 1 0 0 1 1 1 1 Nicastrin DUF2414 PF10309.4 EGC39509.1 - 0.088 12.4 0.3 0.18 11.5 0.2 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF2414) Ank_2 PF12796.2 EGC39510.1 - 0.0044 17.3 0.1 0.041 14.2 0.0 2.6 3 0 0 3 3 3 1 Ankyrin repeats (3 copies) NmrA PF05368.8 EGC39511.1 - 5.4e-58 195.9 0.0 6.7e-58 195.6 0.0 1.0 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC39511.1 - 3.5e-13 49.9 0.0 4.4e-13 49.6 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding 3Beta_HSD PF01073.14 EGC39511.1 - 1.4e-08 33.8 0.2 2.5e-08 32.9 0.1 1.4 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family Epimerase PF01370.16 EGC39511.1 - 3e-05 23.5 0.2 0.00012 21.5 0.1 2.0 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family adh_short PF00106.20 EGC39511.1 - 0.0015 18.5 0.1 0.0025 17.7 0.1 1.3 1 0 0 1 1 1 1 short chain dehydrogenase KR PF08659.5 EGC39511.1 - 0.0034 17.0 0.0 0.0055 16.4 0.0 1.3 1 0 0 1 1 1 1 KR domain DXP_reductoisom PF02670.11 EGC39511.1 - 0.022 15.3 0.1 0.036 14.6 0.1 1.4 1 0 0 1 1 1 0 1-deoxy-D-xylulose 5-phosphate reductoisomerase Semialdhyde_dh PF01118.19 EGC39511.1 - 0.12 12.6 0.1 0.29 11.4 0.1 1.7 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain Methyltransf_31 PF13847.1 EGC39512.1 - 8.2e-17 61.1 0.0 1.4e-16 60.4 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC39512.1 - 1.1e-14 54.1 0.1 4.2e-14 52.2 0.1 1.8 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_11 PF08241.7 EGC39512.1 - 1e-13 51.5 0.0 1.7e-13 50.8 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC39512.1 - 3.5e-11 43.4 0.0 7.6e-11 42.3 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC39512.1 - 1.1e-10 41.4 0.0 1.4e-10 41.0 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39512.1 - 3.7e-08 33.9 0.0 7e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC39512.1 - 2.1e-07 31.2 0.0 4.5e-07 30.1 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC39512.1 - 1.9e-05 24.0 0.0 3.7e-05 23.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain FmrO PF07091.6 EGC39512.1 - 0.001 18.1 0.0 0.0016 17.4 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) DUF938 PF06080.7 EGC39512.1 - 0.0014 18.2 0.0 0.0031 17.0 0.0 1.5 2 0 0 2 2 2 1 Protein of unknown function (DUF938) Methyltransf_8 PF05148.10 EGC39512.1 - 0.0045 16.6 0.0 0.11 12.1 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase vATP-synt_AC39 PF01992.11 EGC39512.1 - 0.0059 15.7 0.0 0.01 15.0 0.0 1.3 1 0 0 1 1 1 1 ATP synthase (C/AC39) subunit Methyltransf_32 PF13679.1 EGC39512.1 - 0.0069 16.0 0.0 0.01 15.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC39512.1 - 0.012 14.7 0.0 0.015 14.3 0.0 1.3 1 1 0 1 1 1 0 Mycolic acid cyclopropane synthetase Methyltransf_26 PF13659.1 EGC39512.1 - 0.017 15.1 0.0 0.051 13.6 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain NNMT_PNMT_TEMT PF01234.12 EGC39512.1 - 0.028 13.4 0.1 0.061 12.2 0.0 1.6 2 0 0 2 2 2 0 NNMT/PNMT/TEMT family NPHI_C PF08469.5 EGC39512.1 - 0.034 14.0 1.5 0.36 10.7 0.0 2.4 2 1 0 2 2 2 0 Nucleoside triphosphatase I C-terminal PCMT PF01135.14 EGC39512.1 - 0.046 13.2 0.0 0.15 11.6 0.0 1.8 1 1 1 2 2 2 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_2 PF00891.13 EGC39512.1 - 0.063 12.4 0.0 0.14 11.3 0.0 1.5 2 0 0 2 2 2 0 O-methyltransferase Methyltransf_11 PF08241.7 EGC39513.1 - 9.1e-18 64.5 0.0 2e-17 63.4 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC39513.1 - 6.1e-15 55.1 0.1 1.2e-14 54.1 0.0 1.5 1 1 1 2 2 2 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC39513.1 - 6.4e-13 48.3 0.0 1.4e-12 47.2 0.0 1.6 1 1 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_12 PF08242.7 EGC39513.1 - 1.3e-11 44.7 0.0 4.2e-11 43.1 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39513.1 - 8.3e-09 36.0 0.0 1.9e-08 34.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC39513.1 - 4.5e-08 32.9 0.0 6.2e-08 32.5 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC39513.1 - 6.2e-07 29.7 0.0 1.6e-06 28.3 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_8 PF05148.10 EGC39513.1 - 0.0014 18.3 0.0 0.004 16.8 0.0 1.9 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_16 PF10294.4 EGC39513.1 - 0.0015 18.0 0.0 0.0025 17.2 0.0 1.4 1 0 0 1 1 1 1 Putative methyltransferase MTS PF05175.9 EGC39513.1 - 0.0028 17.0 0.0 0.0055 16.0 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase small domain DUF938 PF06080.7 EGC39513.1 - 0.0031 17.0 0.0 0.0053 16.3 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF938) Sec15 PF04091.7 EGC39513.1 - 0.006 15.9 0.2 0.079 12.2 0.1 2.0 2 0 0 2 2 2 1 Exocyst complex subunit Sec15-like FmrO PF07091.6 EGC39513.1 - 0.0087 15.0 0.0 0.014 14.4 0.0 1.3 1 0 0 1 1 1 1 Ribosomal RNA methyltransferase (FmrO) PrmA PF06325.8 EGC39513.1 - 0.0091 15.1 0.0 0.017 14.2 0.0 1.4 1 1 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC39513.1 - 0.015 15.3 0.0 0.04 13.9 0.0 1.7 1 1 0 1 1 1 0 Methyltransferase domain FtsJ PF01728.14 EGC39513.1 - 0.015 15.2 0.0 0.079 12.9 0.0 1.9 1 1 0 1 1 1 0 FtsJ-like methyltransferase PCMT PF01135.14 EGC39513.1 - 0.016 14.7 0.0 0.031 13.7 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_32 PF13679.1 EGC39513.1 - 0.1 12.2 0.0 0.18 11.4 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain PS_Dcarbxylase PF02666.10 EGC39514.1 - 6.8e-64 214.8 0.0 8.8e-64 214.5 0.0 1.1 1 0 0 1 1 1 1 Phosphatidylserine decarboxylase Dicty_REP PF05086.7 EGC39514.1 - 3 5.4 4.4 3.6 5.2 2.7 1.3 2 0 0 2 2 2 0 Dictyostelium (Slime Mold) REP protein PHP PF02811.14 EGC39515.1 - 1.1e-09 38.3 0.2 2.6e-09 37.0 0.0 1.8 2 0 0 2 2 2 1 PHP domain MacB_PCD PF12704.2 EGC39515.1 - 0.041 13.4 2.0 2.1 7.8 0.0 2.9 3 0 0 3 3 3 0 MacB-like periplasmic core domain Ost4 PF10215.4 EGC39515.1 - 0.5 9.8 2.7 1 8.9 1.9 1.5 1 0 0 1 1 1 0 Oligosaccaryltransferase PHP PF02811.14 EGC39516.1 - 3.5e-11 43.1 0.0 2.1e-10 40.6 0.0 2.1 1 1 0 1 1 1 1 PHP domain Surface_Ag_2 PF01617.12 EGC39517.1 - 9.4 5.3 8.8 1.6 7.8 1.8 2.1 2 0 0 2 2 2 0 Surface antigen VWC PF00093.13 EGC39518.1 - 0.0041 17.1 7.0 0.0041 17.1 4.8 10.6 8 3 2 10 10 10 7 von Willebrand factor type C domain FNIP PF05725.7 EGC39519.1 - 7.7e-84 275.4 40.3 1.1e-13 50.8 1.4 9.1 7 2 0 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC39519.1 - 1.7e-12 47.0 9.8 0.091 12.7 0.0 10.1 7 2 4 11 11 11 3 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC39519.1 - 0.0045 16.9 0.0 1.9 8.5 0.0 4.1 2 2 1 4 4 4 1 Phage minor tail protein DUF717 PF05338.7 EGC39519.1 - 0.11 12.5 0.0 18 5.3 0.0 2.9 2 0 0 2 2 2 0 Protein of unknown function (DUF717) RhoGEF PF00621.15 EGC39520.1 - 1.7e-49 168.1 3.2 1.7e-49 168.1 2.2 2.8 3 0 0 3 3 3 1 RhoGEF domain PH PF00169.24 EGC39520.1 - 9.3e-20 70.7 2.1 1.2e-11 44.6 0.1 3.1 2 1 1 3 3 3 2 PH domain PH_11 PF15413.1 EGC39520.1 - 0.009 16.2 3.7 0.086 13.0 0.3 3.7 3 1 0 3 3 3 1 Pleckstrin homology domain IQ PF00612.22 EGC39520.1 - 0.063 12.9 0.2 0.063 12.9 0.1 3.9 4 0 0 4 4 4 0 IQ calmodulin-binding motif EB PF01683.13 EGC39521.1 - 0.93 9.6 55.1 0.78 9.8 3.5 7.0 2 2 4 6 6 6 0 EB module Nup35_RRM_2 PF14605.1 EGC39522.1 - 1.3e-10 40.9 0.0 2e-10 40.2 0.0 1.3 1 0 0 1 1 1 1 Nup53/35/40-type RNA recognition motif Nup35_RRM PF05172.8 EGC39522.1 - 8.8e-10 38.2 1.3 1.3e-09 37.7 0.0 1.9 2 0 0 2 2 2 1 Nup53/35/40-type RNA recognition motif Zip PF02535.17 EGC39522.1 - 0.0033 16.4 0.1 0.0044 16.0 0.1 1.1 1 0 0 1 1 1 1 ZIP Zinc transporter NADH5_C PF06455.6 EGC39522.1 - 0.12 11.7 0.8 3 7.1 0.1 2.4 2 1 0 2 2 2 0 NADH dehydrogenase subunit 5 C-terminus RseC_MucC PF04246.7 EGC39522.1 - 0.14 11.6 0.0 0.29 10.6 0.0 1.5 1 0 0 1 1 1 0 Positive regulator of sigma(E), RseC/MucC Ctr PF04145.10 EGC39522.1 - 0.93 9.5 4.6 8.5 6.4 3.2 2.2 1 1 0 1 1 1 0 Ctr copper transporter family Med3 PF11593.3 EGC39522.1 - 5 6.2 21.7 7 5.7 15.0 1.1 1 0 0 1 1 1 0 Mediator complex subunit 3 fungal BAF1_ABF1 PF04684.8 EGC39522.1 - 7 5.3 13.8 8.4 5.1 9.6 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor Methyltransf_7 PF03492.10 EGC39524.1 - 9.8e-09 34.4 10.9 4.2e-06 25.7 0.5 3.2 2 1 1 3 3 3 3 SAM dependent carboxyl methyltransferase Methyltransf_11 PF08241.7 EGC39524.1 - 0.003 18.0 0.0 0.0073 16.7 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC39524.1 - 0.091 12.4 0.0 0.15 11.7 0.0 1.4 1 0 0 1 1 1 0 Methyltransferase domain G6PD_C PF02781.11 EGC39525.1 - 0.019 13.8 0.2 0.028 13.2 0.2 1.2 1 0 0 1 1 1 0 Glucose-6-phosphate dehydrogenase, C-terminal domain Fib_alpha PF08702.5 EGC39525.1 - 0.21 11.7 2.2 0.47 10.5 1.5 1.6 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family Cor1 PF04803.7 EGC39525.1 - 1.4 8.7 9.6 11 5.7 6.7 2.1 1 1 0 1 1 1 0 Cor1/Xlr/Xmr conserved region TnpB_IS66 PF05717.8 EGC39527.1 - 7.1 6.1 24.7 17 4.8 0.4 5.5 1 1 4 5 5 5 0 IS66 Orf2 like protein TraB PF01963.12 EGC39529.1 - 1.3e-11 44.5 0.0 1.6e-11 44.1 0.0 1.3 1 0 0 1 1 1 1 TraB family DUF399 PF04187.8 EGC39529.1 - 0.016 14.7 0.0 0.025 14.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function, DUF399 Skp1 PF01466.14 EGC39529.1 - 0.089 12.8 0.0 0.18 11.8 0.0 1.5 1 0 0 1 1 1 0 Skp1 family, dimerisation domain DRTGG PF07085.7 EGC39529.1 - 0.1 12.1 0.0 0.2 11.2 0.0 1.4 1 0 0 1 1 1 0 DRTGG domain LRR_6 PF13516.1 EGC39530.1 - 5.7e-13 47.4 37.6 0.15 12.2 0.0 12.2 12 0 0 12 12 12 7 Leucine Rich repeat LRR_1 PF00560.28 EGC39530.1 - 0.00039 20.0 23.3 1.4 9.2 0.0 10.0 9 2 0 9 9 9 3 Leucine Rich Repeat Myb_DNA-binding PF00249.26 EGC39531.1 - 3.7e-48 161.3 14.8 1.5e-17 63.3 1.4 3.1 3 0 0 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_6 PF13921.1 EGC39531.1 - 1.7e-41 140.1 14.9 8.5e-20 70.6 1.4 3.0 1 1 2 3 3 3 3 Myb-like DNA-binding domain Myb_DNA-bind_4 PF13837.1 EGC39531.1 - 3.8e-05 23.7 12.9 0.21 11.7 0.3 3.8 2 1 1 3 3 3 3 Myb/SANT-like DNA-binding domain Rap1_C PF11626.3 EGC39531.1 - 0.00026 20.8 2.6 0.32 10.8 0.0 2.2 1 1 1 2 2 2 2 TRF2-interacting telomeric protein/Rap1 - C terminal domain Myb_DNA-bind_2 PF08914.6 EGC39531.1 - 0.046 13.5 5.6 2 8.2 0.0 3.7 2 2 1 3 3 3 0 Rap1 Myb domain DUF1539 PF07560.6 EGC39531.1 - 0.17 11.7 5.7 2.9 7.7 2.3 2.6 1 1 1 2 2 2 0 Domain of Unknown Function (DUF1539) FB_lectin PF07367.6 EGC39531.1 - 0.45 10.1 2.2 0.49 10.0 0.3 2.0 2 1 0 2 2 2 0 Fungal fruit body lectin DUP PF00674.13 EGC39531.1 - 1.4 8.9 4.8 3.9 7.4 0.2 3.0 2 2 0 3 3 3 0 DUP family DCD PF06559.6 EGC39535.1 - 0.067 11.5 0.1 0.088 11.1 0.0 1.3 1 0 0 1 1 1 0 2'-deoxycytidine 5'-triphosphate deaminase (DCD) FAD_binding_1 PF00667.15 EGC39536.1 - 6.7e-45 153.2 0.9 9.9e-45 152.6 0.1 1.7 2 0 0 2 2 2 1 FAD binding domain Flavodoxin_1 PF00258.20 EGC39536.1 - 2.7e-28 98.7 0.1 9.4e-28 97.0 0.0 1.9 2 0 0 2 2 2 1 Flavodoxin NAD_binding_1 PF00175.16 EGC39536.1 - 6.1e-21 75.0 0.0 2.3e-20 73.1 0.0 2.1 2 0 0 2 2 2 1 Oxidoreductase NAD-binding domain Flavodoxin_5 PF12724.2 EGC39536.1 - 6.2e-05 23.0 0.0 0.00071 19.5 0.0 2.5 2 0 0 2 2 2 1 Flavodoxin domain NAD_binding_6 PF08030.7 EGC39536.1 - 0.00056 19.8 0.1 0.0076 16.1 0.0 2.5 2 0 0 2 2 2 1 Ferric reductase NAD binding domain Flavodoxin_NdrI PF07972.6 EGC39536.1 - 0.05 13.5 0.0 0.15 11.9 0.0 1.8 1 0 0 1 1 1 0 NrdI Flavodoxin like SPG48 PF14764.1 EGC39537.1 - 1.8e-92 310.2 6.7 1.8e-92 310.2 4.6 2.5 2 1 0 2 2 2 1 AP-5 complex subunit, vesicle trafficking Pex14_N PF04695.8 EGC39537.1 - 2 8.4 8.0 15 5.6 1.8 2.4 2 0 0 2 2 2 0 Peroxisomal membrane anchor protein (Pex14p) conserved region CPW_WPC PF09717.5 EGC39538.1 - 0.016 15.7 50.2 30 5.3 0.2 10.3 2 1 2 4 4 4 0 Plasmodium falciparum domain of unknown function (CPW_WPC) Chordopox_G3 PF06129.7 EGC39538.1 - 0.58 10.3 6.6 0.94 9.6 4.6 1.3 1 0 0 1 1 1 0 Chordopoxvirus G3 protein ETRAMP PF09716.5 EGC39538.1 - 0.62 10.0 2.5 1.3 9.0 1.7 1.5 1 0 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) Cnd1 PF12717.2 EGC39540.1 - 1.3e-53 181.5 0.2 1.3e-53 181.5 0.1 6.4 6 2 0 6 6 6 2 non-SMC mitotic condensation complex subunit 1 Cnd1_N PF12922.2 EGC39540.1 - 1.9e-25 89.4 1.2 1.9e-25 89.4 0.8 5.3 5 1 0 5 5 5 1 non-SMC mitotic condensation complex subunit 1, N-term HEAT_2 PF13646.1 EGC39540.1 - 1.1e-06 28.8 0.0 0.97 9.7 0.0 5.5 4 1 1 5 5 5 2 HEAT repeats HEAT PF02985.17 EGC39540.1 - 0.00058 19.7 0.1 15 5.9 0.0 5.1 6 0 0 6 6 6 1 HEAT repeat QueF PF14489.1 EGC39540.1 - 0.0052 16.6 2.8 1.7 8.6 0.0 4.1 3 0 0 3 3 3 1 QueF-like protein HEAT_EZ PF13513.1 EGC39540.1 - 0.14 12.6 0.0 84 3.8 0.0 4.2 3 1 1 4 4 4 0 HEAT-like repeat Abi PF02517.11 EGC39541.1 - 2.9e-14 52.9 5.8 2.9e-14 52.9 4.0 1.8 2 0 0 2 2 2 1 CAAX protease self-immunity Zip PF02535.17 EGC39541.1 - 1.1 8.1 5.5 1.2 8.1 0.0 2.5 1 1 1 2 2 2 0 ZIP Zinc transporter ketoacyl-synt PF00109.21 EGC39542.1 - 2.2e-67 227.2 0.0 3.4e-67 226.5 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC39542.1 - 3.4e-52 177.7 0.0 5.2e-52 177.1 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC39542.1 - 5.1e-38 130.4 0.0 9.6e-38 129.5 0.0 1.5 1 0 0 1 1 1 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC39542.1 - 4.9e-30 103.8 0.0 1e-29 102.7 0.0 1.6 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC39542.1 - 3.4e-28 98.5 0.0 1.3e-22 80.2 0.0 3.5 3 0 0 3 3 3 2 KR domain adh_short PF00106.20 EGC39542.1 - 5.4e-21 75.2 0.0 2.4e-15 56.8 0.0 3.6 3 0 0 3 3 3 2 short chain dehydrogenase PS-DH PF14765.1 EGC39542.1 - 6e-13 48.6 0.0 9.3e-13 47.9 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC39542.1 - 6.5e-10 39.9 0.0 2.3e-09 38.2 0.0 2.0 2 0 0 2 2 1 1 Zinc-binding dehydrogenase Epimerase PF01370.16 EGC39542.1 - 3.3e-09 36.5 0.0 1.1e-06 28.2 0.0 2.7 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EGC39542.1 - 2e-08 33.9 0.1 7.2e-08 32.1 0.0 2.0 2 0 0 2 2 2 1 Alcohol dehydrogenase GroES-like domain ADH_zinc_N PF00107.21 EGC39542.1 - 7.2e-08 32.0 0.0 5.7e-07 29.1 0.0 2.5 2 0 0 2 2 2 1 Zinc-binding dehydrogenase Methyltransf_12 PF08242.7 EGC39542.1 - 4.9e-07 30.1 0.0 4.9e-07 30.1 0.0 3.7 3 0 0 3 3 2 1 Methyltransferase domain PP-binding PF00550.20 EGC39542.1 - 3.5e-06 27.1 0.0 1.2e-05 25.4 0.0 2.0 1 0 0 1 1 1 1 Phosphopantetheine attachment site Methyltransf_23 PF13489.1 EGC39542.1 - 1e-05 25.3 0.0 0.00046 19.9 0.0 3.2 3 0 0 3 3 3 1 Methyltransferase domain Thiolase_N PF00108.18 EGC39542.1 - 0.00071 18.6 0.1 0.0014 17.6 0.1 1.4 1 0 0 1 1 1 1 Thiolase, N-terminal domain Semialdhyde_dh PF01118.19 EGC39542.1 - 0.00088 19.5 0.0 0.2 11.9 0.0 3.3 3 0 0 3 3 3 1 Semialdehyde dehydrogenase, NAD binding domain NAD_binding_10 PF13460.1 EGC39542.1 - 0.002 18.1 0.0 0.3 11.0 0.0 3.6 3 1 0 3 3 2 1 NADH(P)-binding Methyltransf_18 PF12847.2 EGC39542.1 - 0.0042 17.6 0.0 0.04 14.4 0.0 2.8 3 0 0 3 3 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39542.1 - 0.083 13.3 0.0 1.1 9.8 0.0 3.1 4 0 0 4 4 1 0 Methyltransferase domain ArgK PF03308.11 EGC39542.1 - 0.41 9.3 0.3 1.5 7.5 0.0 1.9 2 0 0 2 2 2 0 ArgK protein DUF4282 PF14110.1 EGC39543.1 - 1.3e-10 41.3 7.2 1.6e-10 41.0 5.0 1.1 1 0 0 1 1 1 1 Domain of unknown function (DUF4282) Shisa PF13908.1 EGC39543.1 - 0.0011 19.1 1.0 0.0011 19.1 0.7 2.0 1 1 1 2 2 2 1 Wnt and FGF inhibitory regulator Tetraspannin PF00335.15 EGC39543.1 - 0.016 14.5 0.2 0.024 13.9 0.2 1.3 1 0 0 1 1 1 0 Tetraspanin family Tic20 PF09685.5 EGC39543.1 - 0.78 9.7 6.1 1.1 9.2 4.3 1.2 1 0 0 1 1 1 0 Tic20-like protein polyprenyl_synt PF00348.12 EGC39544.1 - 1.4e-67 227.2 0.0 1.8e-67 226.9 0.0 1.1 1 0 0 1 1 1 1 Polyprenyl synthetase Aminotran_5 PF00266.14 EGC39545.1 - 2e-95 319.6 0.0 2.4e-95 319.4 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Beta_elim_lyase PF01212.16 EGC39545.1 - 1.8e-10 40.4 0.0 2.5e-10 39.9 0.0 1.1 1 0 0 1 1 1 1 Beta-eliminating lyase DegT_DnrJ_EryC1 PF01041.12 EGC39545.1 - 8.6e-06 25.0 0.0 1.5e-05 24.2 0.0 1.3 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family Cys_Met_Meta_PP PF01053.15 EGC39545.1 - 0.0012 17.2 0.0 0.0019 16.5 0.0 1.3 1 0 0 1 1 1 1 Cys/Met metabolism PLP-dependent enzyme Ribosomal_S24e PF01282.14 EGC39545.1 - 0.0024 17.6 0.0 0.0076 16.0 0.0 1.8 2 0 0 2 2 2 1 Ribosomal protein S24e Pyridoxal_deC PF00282.14 EGC39545.1 - 0.01 14.3 0.0 0.018 13.5 0.0 1.4 1 0 0 1 1 1 0 Pyridoxal-dependent decarboxylase conserved domain MIP PF00230.15 EGC39546.1 - 1.2e-50 172.1 13.5 1.5e-50 171.7 9.3 1.0 1 0 0 1 1 1 1 Major intrinsic protein YhfT PF10797.4 EGC39546.1 - 0.00049 19.0 0.5 0.00049 19.0 0.3 2.2 2 1 0 2 2 2 1 Protein of unknown function EpuA PF11772.3 EGC39546.1 - 0.073 12.5 2.3 0.28 10.6 1.6 2.0 1 0 0 1 1 1 0 DNA-directed RNA polymerase subunit beta Peptidase_M20 PF01546.23 EGC39547.1 - 4.5e-22 78.4 0.0 7.2e-22 77.8 0.0 1.3 1 0 0 1 1 1 1 Peptidase family M20/M25/M40 M20_dimer PF07687.9 EGC39547.1 - 3.3e-14 52.5 0.0 8.8e-14 51.2 0.0 1.8 1 1 0 1 1 1 1 Peptidase dimerisation domain Sulfate_transp PF00916.15 EGC39550.1 - 2.4e-63 213.8 15.5 4.7e-63 212.8 10.7 1.5 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGC39550.1 - 3.6e-30 103.4 4.1 3.6e-30 103.4 2.8 2.8 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGC39550.1 - 6.7e-18 64.2 0.2 1.6e-17 63.0 0.1 1.7 1 0 0 1 1 1 1 STAS domain DUF3525 PF12039.3 EGC39550.1 - 0.022 13.2 0.1 0.022 13.2 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3525) Sulfate_transp PF00916.15 EGC39551.1 - 2.8e-66 223.3 15.9 6.6e-66 222.1 11.0 1.7 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGC39551.1 - 4e-28 96.8 4.7 4e-28 96.8 3.3 2.6 2 0 0 2 2 2 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGC39551.1 - 3.1e-20 71.7 0.5 1.9e-19 69.1 0.2 2.5 1 1 1 2 2 2 1 STAS domain STAS_2 PF13466.1 EGC39551.1 - 0.27 11.3 0.0 0.44 10.6 0.0 1.3 1 0 0 1 1 1 0 STAS domain CBM_14 PF01607.19 EGC39552.1 - 0.15 12.0 4.6 0.12 12.2 1.2 1.9 2 0 0 2 2 2 0 Chitin binding Peritrophin-A domain Prokineticin PF06607.6 EGC39552.1 - 0.3 11.2 2.5 4.3 7.4 1.7 2.0 1 1 0 1 1 1 0 Prokineticin Meleagrin PF08189.6 EGC39552.1 - 0.41 10.1 3.6 0.64 9.5 1.8 2.0 1 1 1 2 2 2 0 Meleagrin/Cygnin family UPF0506 PF11703.3 EGC39552.1 - 5.7 6.9 6.7 1.4 8.9 0.5 2.1 1 1 1 2 2 2 0 UPF0506 PMM PF03332.8 EGC39553.1 - 8.2e-101 336.1 3.6 9.5e-101 335.9 2.5 1.0 1 0 0 1 1 1 1 Eukaryotic phosphomannomutase Hydrolase_3 PF08282.7 EGC39553.1 - 8.5e-07 28.8 0.0 1.5e-06 28.0 0.0 1.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase PF00702.21 EGC39553.1 - 0.026 14.9 0.0 0.034 14.5 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase DUF600 PF04634.7 EGC39553.1 - 0.04 13.9 0.0 0.073 13.0 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function, DUF600 S6PP PF05116.8 EGC39553.1 - 0.072 12.3 0.0 0.96 8.6 0.0 2.0 2 0 0 2 2 2 0 Sucrose-6F-phosphate phosphohydrolase TMPIT PF07851.8 EGC39553.1 - 0.077 12.0 0.0 0.11 11.6 0.0 1.1 1 0 0 1 1 1 0 TMPIT-like protein Calpain_III PF01067.17 EGC39554.1 - 2e-74 248.0 7.0 6.4e-23 81.0 0.1 4.9 5 0 0 5 5 5 4 Calpain large subunit, domain III Pkinase PF00069.20 EGC39554.1 - 2.9e-67 226.5 0.0 5.7e-66 222.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39554.1 - 3e-50 170.7 0.0 1.1e-49 168.9 0.0 1.8 2 0 0 2 2 2 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC39554.1 - 0.022 13.7 0.0 0.041 12.8 0.0 1.4 1 0 0 1 1 1 0 Kinase-like DNA_pol_phi PF04931.8 EGC39555.1 - 1.2e-28 99.3 39.4 2.1e-22 78.7 22.9 4.5 4 1 0 4 4 4 2 DNA polymerase phi PhyH PF05721.8 EGC39556.1 - 2.1e-47 161.8 0.0 2.5e-47 161.6 0.0 1.1 1 0 0 1 1 1 1 Phytanoyl-CoA dioxygenase (PhyH) Mito_carr PF00153.22 EGC39558.1 - 1.8e-09 37.1 0.1 0.00021 20.9 0.0 2.5 2 0 0 2 2 2 2 Mitochondrial carrier protein GST_N_3 PF13417.1 EGC39559.1 - 8.6e-13 48.3 0.0 2.7e-12 46.7 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C PF00043.20 EGC39559.1 - 1.6e-11 44.0 0.0 3e-11 43.1 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_N_2 PF13409.1 EGC39559.1 - 4.2e-11 42.6 0.0 7.9e-11 41.8 0.0 1.5 1 0 0 1 1 1 1 Glutathione S-transferase, N-terminal domain GST_N PF02798.15 EGC39559.1 - 5.1e-10 39.3 0.0 1.5e-09 37.9 0.0 1.7 2 0 0 2 2 2 1 Glutathione S-transferase, N-terminal domain GST_C_2 PF13410.1 EGC39559.1 - 3.9e-07 29.8 0.0 1.3e-06 28.2 0.0 1.8 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain GST_C_3 PF14497.1 EGC39559.1 - 2.6e-06 27.8 0.0 4.1e-06 27.1 0.0 1.3 1 0 0 1 1 1 1 Glutathione S-transferase, C-terminal domain F-box-like PF12937.2 EGC39561.1 - 0.0014 18.2 0.5 0.0056 16.3 0.1 2.0 2 0 0 2 2 2 1 F-box-like DHQ_synthase PF01761.15 EGC39561.1 - 0.0033 16.3 0.0 0.007 15.3 0.0 1.5 1 0 0 1 1 1 1 3-dehydroquinate synthase IBN_N PF03810.14 EGC39562.1 - 2.6e-10 40.0 1.0 1.3e-09 37.8 0.0 2.7 2 0 0 2 2 2 1 Importin-beta N-terminal domain HEAT PF02985.17 EGC39562.1 - 0.011 15.7 0.0 21 5.5 0.0 3.8 3 0 0 3 3 3 0 HEAT repeat Xpo1 PF08389.7 EGC39562.1 - 0.015 15.2 0.0 0.015 15.2 0.0 4.3 6 1 1 7 7 7 0 Exportin 1-like protein HEAT_2 PF13646.1 EGC39562.1 - 0.032 14.5 0.0 3.6 7.9 0.0 3.4 3 0 0 3 3 3 0 HEAT repeats DUF4611 PF15387.1 EGC39562.1 - 0.56 10.3 7.7 2 8.6 5.3 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4611) RXT2_N PF08595.6 EGC39562.1 - 2.9 7.6 8.9 3.3 7.4 4.0 2.4 2 0 0 2 2 2 0 RXT2-like, N-terminal SET PF00856.23 EGC39563.1 - 4.3e-09 36.8 0.1 9e-09 35.8 0.1 1.6 1 0 0 1 1 1 1 SET domain zf-RING_6 PF14835.1 EGC39563.1 - 3.2 7.5 8.9 3.5 7.4 0.8 2.7 2 0 0 2 2 2 0 zf-RING of BARD1-type protein WD40 PF00400.27 EGC39565.1 - 6.3e-32 108.3 4.8 2.9e-07 30.1 0.0 6.6 7 0 0 7 7 7 5 WD domain, G-beta repeat Nup160 PF11715.3 EGC39565.1 - 0.0015 16.7 0.6 0.02 13.0 0.0 2.1 2 0 0 2 2 2 2 Nucleoporin Nup120/160 Nucleoporin_N PF08801.6 EGC39565.1 - 0.0091 14.7 3.2 0.075 11.7 0.4 2.8 2 1 1 3 3 3 1 Nup133 N terminal like IQ PF00612.22 EGC39566.1 - 1.7e-08 33.3 9.1 0.0025 17.3 0.2 3.4 3 0 0 3 3 3 3 IQ calmodulin-binding motif LSM PF01423.17 EGC39567.1 - 7e-15 54.3 0.0 9.3e-15 53.9 0.0 1.1 1 0 0 1 1 1 1 LSM domain SM-ATX PF14438.1 EGC39567.1 - 0.14 12.0 0.0 0.2 11.6 0.0 1.2 1 0 0 1 1 1 0 Ataxin 2 SM domain Endotoxin_N PF03945.9 EGC39568.1 - 2.4e-11 43.4 5.5 5.3e-11 42.3 0.2 2.8 2 1 0 2 2 2 2 delta endotoxin, N-terminal domain Syja_N PF02383.13 EGC39569.1 - 2e-32 112.2 8.8 2e-32 112.2 6.1 2.4 2 0 0 2 2 2 1 SacI homology domain IBR PF01485.16 EGC39569.1 - 0.0034 17.2 7.5 0.0098 15.7 5.2 1.8 1 0 0 1 1 1 1 IBR domain FYVE PF01363.16 EGC39569.1 - 0.0081 16.0 6.3 0.02 14.8 4.4 1.6 1 0 0 1 1 1 1 FYVE zinc finger Sulfate_transp PF00916.15 EGC39570.1 - 5.5e-66 222.4 6.4 9.8e-66 221.6 4.4 1.4 1 0 0 1 1 1 1 Sulfate transporter family Sulfate_tra_GLY PF13792.1 EGC39570.1 - 3.9e-28 96.9 3.7 3.9e-28 96.9 2.6 3.8 4 1 0 4 4 4 1 Sulfate transporter N-terminal domain with GLY motif STAS PF01740.16 EGC39570.1 - 2.4e-17 62.4 0.1 4.1e-17 61.6 0.1 1.4 1 0 0 1 1 1 1 STAS domain Na_Ca_ex PF01699.19 EGC39571.1 - 9.2e-18 64.1 29.0 1.2e-11 44.4 9.2 4.3 4 2 1 5 5 5 2 Sodium/calcium exchanger protein DUF307 PF03733.8 EGC39571.1 - 1.2e-13 51.1 16.7 1.2e-13 51.1 11.6 4.3 3 0 0 3 3 3 1 Domain of unknown function (DUF307) P12 PF12669.2 EGC39571.1 - 2.5 8.3 5.1 1.6 8.9 0.0 3.0 2 0 0 2 2 2 0 Virus attachment protein p12 family Daxx PF03344.10 EGC39572.1 - 0.026 13.0 78.4 0.26 9.7 23.4 2.3 2 0 0 2 2 2 0 Daxx Family CDC45 PF02724.9 EGC39572.1 - 0.28 9.1 57.1 0.055 11.4 14.3 2.7 3 0 0 3 3 3 0 CDC45-like protein CENP-T PF15511.1 EGC39572.1 - 5.3 6.1 45.5 0.1 11.7 12.0 2.2 2 0 0 2 2 2 0 Centromere kinetochore component CENP-T Activator_LAG-3 PF11498.3 EGC39573.1 - 0.014 14.1 19.6 0.021 13.6 13.6 1.2 1 0 0 1 1 1 0 Transcriptional activator LAG-3 EIIBC-GUT_N PF03612.9 EGC39573.1 - 0.13 11.8 3.2 0.4 10.2 2.2 1.8 1 0 0 1 1 1 0 Sorbitol phosphotransferase enzyme II N-terminus DivIC PF04977.10 EGC39573.1 - 0.17 11.3 10.1 0.58 9.6 7.0 1.9 1 0 0 1 1 1 0 Septum formation initiator DUF4175 PF13779.1 EGC39573.1 - 0.43 8.2 15.6 0.55 7.8 10.8 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) BAF1_ABF1 PF04684.8 EGC39573.1 - 3.6 6.3 16.3 5.6 5.7 11.3 1.2 1 0 0 1 1 1 0 BAF1 / ABF1 chromatin reorganising factor ATAD4 PF15321.1 EGC39573.1 - 4.7 8.2 9.5 13 6.9 4.5 2.6 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 Tim17 PF02466.14 EGC39574.1 - 3.3e-18 65.9 3.5 5.3e-18 65.3 2.4 1.3 1 0 0 1 1 1 1 Tim17/Tim22/Tim23/Pmp24 family FGE-sulfatase PF03781.11 EGC39575.1 - 4.1e-48 164.0 0.2 5.8e-48 163.5 0.1 1.2 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 DUF1371 PF07115.6 EGC39575.1 - 0.0043 17.1 2.4 0.14 12.3 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function (DUF1371) FGE-sulfatase PF03781.11 EGC39576.1 - 2.2e-48 164.9 0.0 2.9e-48 164.5 0.0 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 FGE-sulfatase PF03781.11 EGC39577.1 - 1.7e-50 171.8 2.1 2.2e-50 171.4 1.4 1.1 1 0 0 1 1 1 1 Sulfatase-modifying factor enzyme 1 Tweety PF04906.8 EGC39577.1 - 0.044 12.1 0.0 0.052 11.9 0.0 1.1 1 0 0 1 1 1 0 Tweety Zip PF02535.17 EGC39580.1 - 1.5e-32 112.8 25.4 2.2e-21 76.2 14.4 3.0 1 1 1 2 2 2 2 ZIP Zinc transporter DUF883 PF05957.8 EGC39581.1 - 4.1e-12 46.3 25.8 0.00094 19.5 3.4 5.0 1 1 4 5 5 5 4 Bacterial protein of unknown function (DUF883) Apolipoprotein PF01442.13 EGC39581.1 - 4.7e-08 32.7 4.4 7.8e-07 28.8 2.6 2.4 1 1 0 1 1 1 1 Apolipoprotein A1/A4/E domain Prominin PF05478.6 EGC39581.1 - 1.4e-07 29.4 11.1 1.8e-07 29.1 7.7 1.1 1 0 0 1 1 1 1 Prominin YtxH PF12732.2 EGC39581.1 - 6.6e-07 29.6 44.4 0.95 9.8 9.5 5.8 2 2 1 3 3 3 1 YtxH-like protein Tape_meas_lam_C PF09718.5 EGC39581.1 - 0.0018 18.1 32.8 0.3 11.0 2.0 5.9 2 2 5 7 7 7 3 Lambda phage tail tape-measure protein (Tape_meas_lam_C) WXG100 PF06013.7 EGC39581.1 - 0.0096 15.9 22.2 0.12 12.4 4.2 4.2 1 1 4 5 5 5 3 Proteins of 100 residues with WXG ApoO PF09769.4 EGC39581.1 - 0.03 14.0 9.2 0.96 9.1 0.4 3.8 1 1 2 4 4 4 0 Apolipoprotein O DBD_Tnp_Hermes PF10683.4 EGC39581.1 - 0.076 12.4 0.4 0.21 11.0 0.3 1.7 1 0 0 1 1 1 0 Hermes transposase DNA-binding domain NOB1_Zn_bind PF08772.6 EGC39581.1 - 0.091 12.5 0.7 0.21 11.4 0.5 1.5 1 0 0 1 1 1 0 Nin one binding (NOB1) Zn-ribbon like ApoLp-III PF07464.6 EGC39581.1 - 0.24 11.4 30.8 0.24 11.4 6.8 2.8 1 1 1 2 2 2 0 Apolipophorin-III precursor (apoLp-III) DUF1798 PF08807.5 EGC39581.1 - 0.25 11.0 16.6 0.38 10.5 0.4 4.4 1 1 3 4 4 4 0 Bacterial domain of unknown function (DUF1798) DUF3708 PF12501.3 EGC39581.1 - 0.31 10.8 9.4 1.8 8.4 0.1 3.1 1 1 2 3 3 3 0 Phosphate ATP-binding cassette transporter DUF3584 PF12128.3 EGC39581.1 - 0.41 7.9 26.5 0.19 9.0 4.3 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF3584) DUF4175 PF13779.1 EGC39581.1 - 0.44 8.2 20.9 1.9 6.0 4.7 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4175) Uteroglobin PF01099.12 EGC39581.1 - 0.62 9.9 6.0 13 5.6 0.0 3.9 3 1 1 4 4 4 0 Uteroglobin family VitK2_biosynth PF02621.9 EGC39581.1 - 1.3 8.1 6.0 0.95 8.6 0.3 2.7 2 1 1 3 3 3 0 Menaquinone biosynthesis PhaP_Bmeg PF09602.5 EGC39581.1 - 1.7 8.4 24.2 2.1 8.1 5.4 3.7 1 1 2 3 3 3 0 Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg) p450 PF00067.17 EGC39581.1 - 3 6.2 6.2 7.5 4.9 4.3 1.7 1 1 0 1 1 1 0 Cytochrome P450 YbjQ_1 PF01906.12 EGC39581.1 - 3.1 8.2 16.5 3.6 8.0 0.3 4.6 1 1 4 5 5 5 0 Putative heavy-metal-binding DUF2317 PF10079.4 EGC39581.1 - 4.1 5.8 17.3 1.1 7.7 3.1 2.1 1 1 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2317) OmpH PF03938.9 EGC39581.1 - 4.7 7.1 26.3 2.2 8.1 9.3 2.6 1 1 1 2 2 2 0 Outer membrane protein (OmpH-like) YlqD PF11068.3 EGC39581.1 - 6.6 6.7 11.6 72 3.4 0.5 3.2 1 1 2 3 3 3 0 YlqD protein ATP-synt_B PF00430.13 EGC39581.1 - 7.2 6.4 32.8 7.2 6.4 7.1 3.8 1 1 3 4 4 4 0 ATP synthase B/B' CF(0) AAA_13 PF13166.1 EGC39581.1 - 8.5 4.7 33.6 7.9 4.8 9.8 2.0 1 1 1 2 2 2 0 AAA domain RRF PF01765.14 EGC39581.1 - 9.5 5.6 30.6 6.4 6.2 3.8 3.8 1 1 3 4 4 4 0 Ribosome recycling factor DUF948 PF06103.6 EGC39581.1 - 9.7 6.1 14.9 8 6.3 0.0 4.5 1 1 3 4 4 4 0 Bacterial protein of unknown function (DUF948) ThiF PF00899.16 EGC39582.1 - 2.3e-43 147.2 0.2 4.8e-43 146.2 0.1 1.5 1 0 0 1 1 1 1 ThiF family MoeZ_MoeB PF05237.8 EGC39582.1 - 1.1e-31 108.2 0.0 2.5e-31 107.0 0.0 1.7 1 0 0 1 1 1 1 MoeZ/MoeB domain Rhodanese PF00581.15 EGC39582.1 - 1.8e-07 31.4 0.0 3.9e-07 30.4 0.0 1.6 1 0 0 1 1 1 1 Rhodanese-like domain ApbA PF02558.11 EGC39582.1 - 0.00063 19.2 0.2 0.0016 17.9 0.1 1.6 1 0 0 1 1 1 1 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGC39582.1 - 0.0013 18.8 0.1 0.0035 17.4 0.1 1.7 1 1 0 1 1 1 1 Shikimate / quinate 5-dehydrogenase FAD_binding_3 PF01494.14 EGC39582.1 - 0.0074 15.3 0.1 0.011 14.8 0.0 1.3 1 0 0 1 1 1 1 FAD binding domain NdhM PF10664.4 EGC39582.1 - 0.019 14.8 1.5 0.61 10.0 1.0 2.5 1 1 0 1 1 1 0 Cyanobacterial and plastid NDH-1 subunit M DAO PF01266.19 EGC39582.1 - 0.023 13.6 3.0 0.034 13.0 2.1 1.2 1 0 0 1 1 1 0 FAD dependent oxidoreductase Pyr_redox PF00070.22 EGC39582.1 - 0.025 14.9 1.0 0.085 13.2 0.3 2.3 2 0 0 2 2 2 0 Pyridine nucleotide-disulphide oxidoreductase 3HCDH_N PF02737.13 EGC39582.1 - 0.025 14.2 0.1 0.047 13.3 0.1 1.5 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain UDPG_MGDP_dh_N PF03721.9 EGC39582.1 - 0.036 13.4 0.7 0.036 13.4 0.5 1.9 2 1 0 2 2 2 0 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain GBP PF02263.14 EGC39583.1 - 7.8e-07 28.4 2.0 0.00034 19.7 0.0 2.5 1 1 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EGC39583.1 - 0.0017 18.3 2.1 0.0019 18.1 0.1 2.1 2 1 0 2 2 2 1 50S ribosome-binding GTPase HSP20 PF00011.16 EGC39583.1 - 0.0054 16.5 1.1 0.0091 15.8 0.2 1.9 2 0 0 2 2 2 1 Hsp20/alpha crystallin family RIH_assoc PF08454.6 EGC39583.1 - 0.48 10.0 5.2 0.2 11.2 0.2 2.8 3 0 0 3 3 3 0 RyR and IP3R Homology associated GBP PF02263.14 EGC39584.1 - 9.7e-07 28.1 3.1 0.00018 20.6 0.0 2.4 1 1 1 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EGC39584.1 - 0.0019 18.1 0.2 0.0019 18.1 0.1 2.2 2 1 0 2 2 2 1 50S ribosome-binding GTPase RIH_assoc PF08454.6 EGC39584.1 - 0.74 9.4 7.1 0.09 12.4 0.3 2.8 3 0 0 3 3 3 0 RyR and IP3R Homology associated GBP PF02263.14 EGC39585.1 - 1.8e-07 30.5 0.9 5.5e-05 22.3 0.0 2.3 2 0 0 2 2 2 2 Guanylate-binding protein, N-terminal domain MMR_HSR1 PF01926.18 EGC39585.1 - 0.00056 19.8 0.2 0.0018 18.2 0.1 1.9 1 0 0 1 1 1 1 50S ribosome-binding GTPase Miro PF08477.8 EGC39585.1 - 0.027 14.9 0.2 0.095 13.2 0.1 2.0 1 0 0 1 1 1 0 Miro-like protein Lectin_legB PF00139.14 EGC39586.1 - 3.4e-15 56.0 6.3 3.4e-15 56.0 4.3 1.8 2 0 0 2 2 2 1 Legume lectin domain Patatin PF01734.17 EGC39587.1 - 4e-24 85.6 0.0 5.6e-24 85.2 0.0 1.2 1 0 0 1 1 1 1 Patatin-like phospholipase Peptidase_S51 PF03575.12 EGC39587.1 - 0.0037 17.0 0.2 0.0097 15.6 0.1 1.7 2 0 0 2 2 2 1 Peptidase family S51 PP-binding PF00550.20 EGC39587.1 - 0.013 15.7 0.1 0.041 14.1 0.0 1.9 2 0 0 2 2 2 0 Phosphopantetheine attachment site SRPRB PF09439.5 EGC39588.1 - 5e-33 113.8 0.2 6.4e-33 113.4 0.1 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit Arf PF00025.16 EGC39588.1 - 1.3e-15 57.0 0.1 1.8e-15 56.6 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39588.1 - 3.7e-10 39.3 0.1 5e-10 38.9 0.1 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region MMR_HSR1 PF01926.18 EGC39588.1 - 3e-08 33.5 0.3 4.6e-08 33.0 0.2 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC39588.1 - 4.3e-07 29.5 0.4 8.7e-06 25.2 0.1 2.1 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain Miro PF08477.8 EGC39588.1 - 1.1e-06 29.1 0.0 2.1e-06 28.2 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Ras PF00071.17 EGC39588.1 - 8.8e-06 25.1 0.1 1.3e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Ras family G-alpha PF00503.15 EGC39588.1 - 2.4e-05 23.2 1.3 0.00098 17.9 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit FeoB_N PF02421.13 EGC39588.1 - 6.2e-05 22.3 0.5 0.0001 21.5 0.3 1.4 1 0 0 1 1 1 1 Ferrous iron transport protein B PduV-EutP PF10662.4 EGC39588.1 - 0.063 12.7 0.6 0.13 11.7 0.4 1.5 1 1 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation TAF4 PF05236.9 EGC39589.1 - 3.7e-33 114.9 10.7 3.7e-33 114.9 7.4 4.6 5 0 0 5 5 5 1 Transcription initiation factor TFIID component TAF4 family SAGA-Tad1 PF12767.2 EGC39589.1 - 0.00031 20.4 12.7 0.00031 20.4 8.8 5.9 2 2 3 5 5 5 1 Transcriptional regulator of RNA polII, SAGA, subunit RhoGAP PF00620.22 EGC39590.1 - 3.5e-08 33.2 1.0 4.7e-08 32.7 0.7 1.1 1 0 0 1 1 1 1 RhoGAP domain DRAT PF07357.6 EGC39590.1 - 0.0066 15.6 0.1 0.01 15.0 0.1 1.3 1 0 0 1 1 1 1 Dinitrogenase reductase ADP-ribosyltransferase (DRAT) TFIIH_BTF_p62_N PF08567.6 EGC39591.1 - 0.13 11.8 3.0 0.42 10.3 0.4 2.5 2 0 0 2 2 2 0 TFIIH p62 subunit, N-terminal domain Ribosomal_L37e PF01907.14 EGC39592.1 - 5e-27 93.4 10.7 5e-27 93.4 7.4 1.5 2 0 0 2 2 2 1 Ribosomal protein L37e DZR PF12773.2 EGC39592.1 - 0.002 17.8 2.1 0.0029 17.3 1.5 1.2 1 0 0 1 1 1 1 Double zinc ribbon SelR PF01641.13 EGC39592.1 - 0.017 14.8 0.2 0.019 14.6 0.2 1.2 1 0 0 1 1 1 0 SelR domain DUF1462 PF07315.6 EGC39592.1 - 0.067 13.1 0.1 0.078 12.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1462) zinc_ribbon_2 PF13240.1 EGC39592.1 - 0.096 12.2 2.8 0.18 11.3 1.9 1.4 1 0 0 1 1 1 0 zinc-ribbon domain zf-ribbon_3 PF13248.1 EGC39592.1 - 0.11 11.7 3.1 0.25 10.6 2.1 1.6 1 1 0 1 1 1 0 zinc-ribbon domain HypA PF01155.14 EGC39592.1 - 0.17 11.5 0.6 0.24 11.0 0.4 1.3 1 0 0 1 1 1 0 Hydrogenase expression/synthesis hypA family GFA PF04828.9 EGC39592.1 - 0.22 11.5 3.9 1.4 8.8 0.3 2.2 1 1 1 2 2 2 0 Glutathione-dependent formaldehyde-activating enzyme zf-C3HC4_2 PF13923.1 EGC39592.1 - 0.57 10.2 3.3 0.91 9.6 2.3 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39592.1 - 1.6 8.4 4.9 2.5 7.8 3.4 1.3 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Prim_Zn_Ribbon PF08273.7 EGC39592.1 - 1.7 8.8 6.1 0.4 10.7 1.3 2.1 2 0 0 2 2 2 0 Zinc-binding domain of primase-helicase RNA_POL_M_15KD PF02150.11 EGC39592.1 - 6.2 6.5 6.3 52 3.6 0.4 2.1 1 1 1 2 2 2 0 RNA polymerases M/15 Kd subunit Aconitase PF00330.15 EGC39593.1 - 4.8e-141 470.4 0.0 6.1e-141 470.0 0.0 1.1 1 0 0 1 1 1 1 Aconitase family (aconitate hydratase) Aconitase_C PF00694.14 EGC39593.1 - 1.1e-39 135.5 0.0 2e-39 134.7 0.0 1.4 1 0 0 1 1 1 1 Aconitase C-terminal domain FNIP PF05725.7 EGC39594.1 - 7.1e-118 384.3 121.1 6.7e-13 48.3 2.0 15.5 6 3 13 20 20 20 20 FNIP Repeat DUF1769 PF08588.5 EGC39594.1 - 3.7e-06 26.7 13.8 4.3 7.3 0.0 8.2 6 2 2 8 8 8 3 Protein of unknown function (DUF1769) DAP10 PF07213.6 EGC39595.1 - 0.21 11.3 0.2 0.52 10.1 0.1 1.6 1 0 0 1 1 1 0 DAP10 membrane protein EGF_2 PF07974.8 EGC39595.1 - 1.5 9.0 15.9 0.37 11.0 8.6 1.9 2 0 0 2 2 2 0 EGF-like domain Dynamin_N PF00350.18 EGC39597.1 - 1e-05 25.3 2.7 1.3e-05 25.0 0.4 2.3 2 0 0 2 2 2 1 Dynamin family Spore_II_R PF09551.5 EGC39597.1 - 0.013 15.5 1.5 0.04 13.9 0.2 2.5 2 0 0 2 2 2 0 Stage II sporulation protein R (spore_II_R) SapB_2 PF03489.12 EGC39598.1 - 0.083 12.9 0.0 0.2 11.7 0.0 1.7 1 0 0 1 1 1 0 Saposin-like type B, region 2 Senescence PF06911.7 EGC39599.1 - 1.8e-29 102.7 0.5 1.8e-29 102.7 0.4 1.9 3 0 0 3 3 3 1 Senescence-associated protein DUF3439 PF11921.3 EGC39599.1 - 0.53 10.0 8.6 1.1 9.0 6.0 1.5 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) TPR_12 PF13424.1 EGC39600.1 - 2.2e-83 274.2 36.6 7.8e-17 60.9 0.5 8.1 3 2 5 9 9 9 8 Tetratricopeptide repeat TPR_1 PF00515.23 EGC39600.1 - 1.8e-39 131.7 39.7 7.3e-09 34.8 0.2 10.9 10 0 0 10 10 10 9 Tetratricopeptide repeat TPR_11 PF13414.1 EGC39600.1 - 1.6e-35 120.5 34.0 7.2e-11 41.5 0.0 8.0 5 2 3 9 9 9 8 TPR repeat TPR_10 PF13374.1 EGC39600.1 - 4.2e-35 118.6 0.0 6e-05 22.8 0.0 10.3 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39600.1 - 5.7e-35 116.4 23.0 5.7e-06 25.8 0.1 11.5 11 0 0 11 11 11 7 Tetratricopeptide repeat TPR_7 PF13176.1 EGC39600.1 - 1.6e-31 105.5 16.6 0.00015 21.2 0.1 10.5 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 EGC39600.1 - 5.1e-21 72.8 65.9 1.5e-05 24.4 1.5 12.2 12 0 0 12 12 12 8 Tetratricopeptide repeat TPR_16 PF13432.1 EGC39600.1 - 5.3e-12 46.0 0.0 0.23 12.1 0.0 5.8 6 0 0 6 6 5 3 Tetratricopeptide repeat TPR_17 PF13431.1 EGC39600.1 - 1.6e-10 40.2 13.3 0.02 15.0 0.0 8.6 9 0 0 9 9 7 2 Tetratricopeptide repeat DUF4062 PF13271.1 EGC39600.1 - 9.3e-10 38.3 3.1 5.2e-09 35.9 0.3 3.5 2 1 0 2 2 1 1 Domain of unknown function (DUF4062) TPR_6 PF13174.1 EGC39600.1 - 2.3e-09 37.0 9.5 1.3 9.6 0.0 8.4 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_14 PF13428.1 EGC39600.1 - 4.6e-08 33.0 0.0 14 6.6 0.0 7.8 8 1 0 8 8 8 0 Tetratricopeptide repeat NACHT PF05729.7 EGC39600.1 - 3.3e-07 30.1 0.1 1.5e-06 27.9 0.0 2.2 3 0 0 3 3 3 1 NACHT domain BRCT PF00533.21 EGC39600.1 - 6e-07 29.5 0.1 6e-07 29.5 0.1 2.8 2 0 0 2 2 2 1 BRCA1 C Terminus (BRCT) domain TPR_19 PF14559.1 EGC39600.1 - 3e-06 27.4 9.2 0.2 11.9 0.0 6.2 4 2 2 6 6 6 1 Tetratricopeptide repeat SHNi-TPR PF10516.4 EGC39600.1 - 0.0017 17.5 6.9 0.28 10.4 0.0 5.2 6 0 0 6 6 6 1 SHNi-TPR MIT PF04212.13 EGC39600.1 - 8.5 6.3 37.7 0.43 10.5 1.2 7.9 8 2 2 10 10 9 0 MIT (microtubule interacting and transport) domain ABC_tran PF00005.22 EGC39601.1 - 1e-34 119.7 0.0 2e-34 118.8 0.0 1.5 1 0 0 1 1 1 1 ABC transporter ABC_membrane PF00664.18 EGC39601.1 - 8.7e-33 113.9 11.7 1.1e-32 113.5 8.1 1.1 1 0 0 1 1 1 1 ABC transporter transmembrane region SMC_N PF02463.14 EGC39601.1 - 4.2e-09 35.9 1.7 3.9e-07 29.5 1.2 2.3 1 1 0 1 1 1 1 RecF/RecN/SMC N terminal domain AAA_21 PF13304.1 EGC39601.1 - 2.3e-07 31.0 5.0 0.00072 19.5 0.1 3.3 2 2 1 3 3 3 2 AAA domain AAA_29 PF13555.1 EGC39601.1 - 0.00015 21.2 0.3 0.001 18.5 0.1 2.3 2 0 0 2 2 2 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC39601.1 - 0.00015 20.9 0.5 0.00043 19.4 0.1 1.9 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA_17 PF13207.1 EGC39601.1 - 0.0003 21.6 0.1 0.001 19.8 0.1 2.1 1 1 0 1 1 1 1 AAA domain DUF815 PF05673.8 EGC39601.1 - 0.00051 19.0 0.0 0.00099 18.1 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF815) AAA_15 PF13175.1 EGC39601.1 - 0.0013 17.8 3.4 0.067 12.2 0.1 2.8 2 1 0 2 2 2 1 AAA ATPase domain Zeta_toxin PF06414.7 EGC39601.1 - 0.0035 16.4 0.0 0.0068 15.5 0.0 1.5 1 0 0 1 1 1 1 Zeta toxin AAA_18 PF13238.1 EGC39601.1 - 0.016 15.5 0.0 0.071 13.4 0.0 2.2 2 0 0 2 2 2 0 AAA domain G-alpha PF00503.15 EGC39601.1 - 0.026 13.2 2.0 0.083 11.5 0.0 2.3 2 1 0 3 3 3 0 G-protein alpha subunit AAA_22 PF13401.1 EGC39601.1 - 0.03 14.4 0.2 0.12 12.5 0.1 2.0 1 1 0 1 1 1 0 AAA domain FtsK_SpoIIIE PF01580.13 EGC39601.1 - 0.034 13.6 0.0 0.075 12.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA PF00004.24 EGC39601.1 - 0.044 13.9 0.1 0.47 10.6 0.1 2.3 1 1 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_16 PF13191.1 EGC39601.1 - 0.05 13.5 0.0 0.086 12.8 0.0 1.5 1 0 0 1 1 1 0 AAA ATPase domain AAA_30 PF13604.1 EGC39601.1 - 0.097 12.2 0.1 0.27 10.7 0.1 1.8 1 1 0 1 1 1 0 AAA domain AAA_33 PF13671.1 EGC39601.1 - 0.17 11.7 0.3 0.43 10.4 0.2 1.7 1 1 0 1 1 1 0 AAA domain SbcCD_C PF13558.1 EGC39601.1 - 0.57 10.1 4.1 0.99 9.3 0.3 2.9 3 1 0 3 3 2 0 Putative exonuclease SbcCD, C subunit adh_short PF00106.20 EGC39602.1 - 6.5e-26 91.2 0.0 8.4e-26 90.8 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC39602.1 - 7.7e-17 61.8 0.0 1.1e-16 61.3 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC39602.1 - 1e-08 35.0 0.0 1.5e-08 34.5 0.0 1.1 1 0 0 1 1 1 1 KR domain 3Beta_HSD PF01073.14 EGC39602.1 - 0.0046 15.6 0.4 0.0074 15.0 0.3 1.3 1 0 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family UQ_con PF00179.21 EGC39603.1 - 1.1e-15 57.2 0.0 1.3e-15 57.0 0.0 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme RWD PF05773.17 EGC39603.1 - 0.0056 16.5 0.0 0.0059 16.4 0.0 1.3 1 0 0 1 1 1 1 RWD domain UEV PF05743.8 EGC39603.1 - 0.082 12.5 0.0 0.12 12.1 0.0 1.3 1 0 0 1 1 1 0 UEV domain BCIP PF13862.1 EGC39605.1 - 2.3e-45 154.5 12.9 2.3e-45 154.5 8.9 2.1 2 1 0 2 2 2 1 p21-C-terminal region-binding protein AIF_C PF14721.1 EGC39605.1 - 0.0096 16.1 2.9 0.0096 16.1 2.0 3.7 2 1 1 3 3 3 1 Apoptosis-inducing factor, mitochondrion-associated, C-term zf-CCHC PF00098.18 EGC39607.1 - 2.7e-08 33.3 2.0 5.3e-08 32.4 1.4 1.5 1 0 0 1 1 1 1 Zinc knuckle DUF605 PF04652.11 EGC39607.1 - 0.14 11.4 5.1 0.18 11.1 3.5 1.3 1 0 0 1 1 1 0 Vta1 like NRDE-2 PF08424.5 EGC39608.1 - 0.079 11.8 4.4 0.11 11.3 3.1 1.1 1 0 0 1 1 1 0 NRDE-2, necessary for RNA interference DUF4131 PF13567.1 EGC39608.1 - 1.3 8.4 5.0 0.75 9.1 1.5 1.9 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Reticulon PF02453.12 EGC39608.1 - 3.9 7.0 15.5 1.3 8.6 4.2 2.4 2 1 0 2 2 2 0 Reticulon DUF1980 PF09323.5 EGC39608.1 - 4 7.1 9.9 3.4 7.3 2.5 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF1980) Methyltransf_31 PF13847.1 EGC39609.1 - 1.5e-18 66.8 0.6 1.9e-18 66.5 0.4 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39609.1 - 2.4e-16 60.3 0.0 3.3e-16 59.8 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain TehB PF03848.9 EGC39609.1 - 1.1e-09 37.7 0.8 3.1e-09 36.2 0.6 1.8 1 1 0 1 1 1 1 Tellurite resistance protein TehB Methyltransf_12 PF08242.7 EGC39609.1 - 2e-09 37.7 0.1 3.1e-09 37.2 0.1 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39609.1 - 1.3e-08 35.1 0.0 2e-08 34.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC39609.1 - 3.2e-08 33.1 0.0 4.2e-08 32.7 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_25 PF13649.1 EGC39609.1 - 6.6e-08 32.8 0.0 1e-07 32.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC39609.1 - 1.8e-07 31.0 0.0 3.6e-07 30.0 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain PrmA PF06325.8 EGC39609.1 - 8.1e-06 25.1 0.0 1e-05 24.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC39609.1 - 3.4e-05 23.8 0.0 5.2e-05 23.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain CMAS PF02353.15 EGC39609.1 - 0.00014 21.0 0.1 0.00017 20.7 0.1 1.1 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase DUF3800 PF12686.2 EGC39609.1 - 0.00096 18.8 1.1 0.0014 18.3 0.8 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3800) TPMT PF05724.6 EGC39609.1 - 0.0012 18.2 0.0 0.0027 17.1 0.0 1.3 1 1 0 1 1 1 1 Thiopurine S-methyltransferase (TPMT) NNMT_PNMT_TEMT PF01234.12 EGC39609.1 - 0.0046 15.9 0.0 0.014 14.3 0.0 1.6 1 1 0 2 2 2 1 NNMT/PNMT/TEMT family Methyltransf_4 PF02390.12 EGC39609.1 - 0.023 13.7 0.0 0.033 13.2 0.0 1.3 1 0 0 1 1 1 0 Putative methyltransferase AdoMet_MTase PF07757.8 EGC39609.1 - 0.037 14.1 0.0 0.07 13.2 0.0 1.5 1 0 0 1 1 1 0 Predicted AdoMet-dependent methyltransferase DOT1 PF08123.8 EGC39609.1 - 0.04 13.2 0.1 0.066 12.5 0.0 1.4 1 0 0 1 1 1 0 Histone methylation protein DOT1 MetW PF07021.7 EGC39609.1 - 0.058 12.7 0.0 0.083 12.2 0.0 1.3 1 0 0 1 1 1 0 Methionine biosynthesis protein MetW UPF0020 PF01170.13 EGC39609.1 - 0.14 11.6 0.0 0.22 11.0 0.0 1.3 1 1 0 1 1 1 0 Putative RNA methylase family UPF0020 TetR_C_8 PF14278.1 EGC39609.1 - 0.35 11.2 3.8 0.74 10.2 0.2 2.4 2 1 0 2 2 2 0 Transcriptional regulator C-terminal region bZIP_1 PF00170.16 EGC39610.1 - 1e-12 47.7 9.1 1e-12 47.7 6.3 2.5 2 0 0 2 2 2 1 bZIP transcription factor bZIP_2 PF07716.10 EGC39610.1 - 0.00016 21.4 15.0 0.00016 21.4 10.4 3.8 2 2 1 3 3 3 1 Basic region leucine zipper bZIP_Maf PF03131.12 EGC39610.1 - 0.0073 16.5 8.2 0.0073 16.5 5.7 3.3 3 0 0 3 3 3 1 bZIP Maf transcription factor DUF4337 PF14235.1 EGC39610.1 - 0.21 11.3 18.1 1.1 9.0 4.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4337) DOMON PF03351.12 EGC39611.1 - 2e-19 69.7 2.0 2.9e-19 69.1 1.4 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EGC39611.1 - 5.2e-14 52.2 13.6 5.2e-14 52.2 9.4 1.9 1 1 1 2 2 2 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGC39611.1 - 6.9 6.2 9.6 3 7.4 3.8 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF2427) Rer1 PF03248.8 EGC39612.1 - 4e-70 235.0 7.3 4.5e-70 234.8 5.1 1.0 1 0 0 1 1 1 1 Rer1 family MFS_1 PF07690.11 EGC39612.1 - 0.27 9.9 8.0 0.42 9.2 5.5 1.2 1 0 0 1 1 1 0 Major Facilitator Superfamily DUF2208 PF09973.4 EGC39612.1 - 3.9 6.6 7.5 0.42 9.8 2.3 1.5 2 0 0 2 2 2 0 Predicted membrane protein (DUF2208) RYDR_ITPR PF01365.16 EGC39613.1 - 3.8e-18 65.4 15.4 3.7e-11 42.6 0.3 6.8 5 2 1 6 6 6 2 RIH domain RNase_HII PF01351.13 EGC39614.1 - 7.5e-49 166.0 0.0 1e-48 165.6 0.0 1.2 1 0 0 1 1 1 1 Ribonuclease HII UPF0118 PF01594.11 EGC39615.1 - 0.026 13.5 0.1 0.038 12.9 0.1 1.2 1 0 0 1 1 1 0 Domain of unknown function DUF20 FNIP PF05725.7 EGC39616.1 - 7.8e-66 217.7 24.6 6.8e-17 61.1 0.4 7.3 6 1 1 7 7 7 7 FNIP Repeat LRR_5 PF13306.1 EGC39616.1 - 3.6e-05 23.4 0.6 0.026 14.2 0.1 3.2 1 1 3 4 4 4 4 Leucine rich repeats (6 copies) DUF1769 PF08588.5 EGC39616.1 - 0.0009 19.1 2.9 1.4 8.9 0.1 4.8 4 2 1 5 5 5 2 Protein of unknown function (DUF1769) WD40 PF00400.27 EGC39617.1 - 1.9e-41 138.5 31.3 3.1e-12 45.8 0.0 7.3 7 0 0 7 7 7 6 WD domain, G-beta repeat NLE PF08154.7 EGC39617.1 - 3.2e-20 71.8 0.1 6e-20 71.0 0.1 1.5 1 0 0 1 1 1 1 NLE (NUC135) domain Nup160 PF11715.3 EGC39617.1 - 2.4e-08 32.6 12.3 0.00077 17.7 0.4 4.9 1 1 2 3 3 3 3 Nucleoporin Nup120/160 Cob_adeno_trans PF01923.13 EGC39618.1 - 8.3e-49 165.5 0.0 1.1e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Cobalamin adenosyltransferase Mitofilin PF09731.4 EGC39619.1 - 1.6 7.2 11.6 2 6.9 8.1 1.1 1 0 0 1 1 1 0 Mitochondrial inner membrane protein Ebp2 PF05890.7 EGC39621.1 - 1e-84 284.0 33.8 1e-84 284.0 23.4 3.5 2 1 1 3 3 3 1 Eukaryotic rRNA processing protein EBP2 DUF1084 PF06454.6 EGC39622.1 - 1.1e-09 37.7 25.9 2.1e-09 36.8 17.9 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) TIG PF01833.19 EGC39623.1 - 1.1e-07 31.7 19.7 0.011 15.6 0.2 5.2 3 2 1 4 4 4 4 IPT/TIG domain Spt5_N PF11942.3 EGC39624.1 - 5.3 7.7 11.1 0.83 10.3 4.7 1.9 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal Pkinase_Tyr PF07714.12 EGC39625.1 - 3.7e-65 219.5 0.0 6.5e-65 218.7 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC39625.1 - 1.7e-50 171.6 0.0 1.7e-50 171.6 0.0 1.9 2 0 0 2 2 2 1 Protein kinase domain LRR_4 PF12799.2 EGC39625.1 - 5.4e-37 124.8 103.9 8.5e-09 34.8 3.4 10.0 5 1 8 13 13 13 10 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC39625.1 - 1.4e-36 124.0 66.0 4.4e-13 48.7 2.9 7.2 6 1 2 8 8 8 5 Leucine rich repeat LRR_1 PF00560.28 EGC39625.1 - 3.4e-11 41.5 89.2 0.11 12.5 1.8 16.4 16 1 0 16 16 16 9 Leucine Rich Repeat LRR_7 PF13504.1 EGC39625.1 - 5e-11 40.9 53.0 0.23 11.7 1.4 13.4 14 0 0 14 14 14 7 Leucine rich repeat LRR_9 PF14580.1 EGC39625.1 - 0.00097 18.7 21.6 0.064 12.8 1.2 4.5 1 1 3 4 4 4 3 Leucine-rich repeat LRR_6 PF13516.1 EGC39625.1 - 0.064 13.3 0.3 0.064 13.3 0.2 13.8 15 0 0 15 15 15 0 Leucine Rich repeat Abi PF02517.11 EGC39626.1 - 1.2e-14 54.1 7.2 1.2e-14 54.1 5.0 2.5 2 1 0 2 2 2 1 CAAX protease self-immunity Yip1 PF04893.12 EGC39626.1 - 0.0088 15.5 5.4 0.0088 15.5 3.7 2.8 2 1 0 2 2 2 1 Yip1 domain DUF543 PF04418.7 EGC39626.1 - 0.17 11.8 0.1 0.17 11.8 0.0 2.4 3 0 0 3 3 3 0 Domain of unknown function (DUF543) Trp_dioxygenase PF03301.8 EGC39627.1 - 0.00053 19.2 4.1 0.00077 18.6 2.9 1.1 1 0 0 1 1 1 1 Tryptophan 2,3-dioxygenase Zip PF02535.17 EGC39627.1 - 0.016 14.1 4.5 0.025 13.5 3.1 1.3 1 0 0 1 1 1 0 ZIP Zinc transporter Mem_trans PF03547.13 EGC39627.1 - 0.034 12.4 7.7 0.047 11.9 5.3 1.1 1 0 0 1 1 1 0 Membrane transport protein Ycf1 PF05758.7 EGC39627.1 - 0.041 11.6 23.1 0.051 11.3 16.0 1.1 1 0 0 1 1 1 0 Ycf1 OmpH PF03938.9 EGC39627.1 - 0.21 11.5 18.0 0.36 10.7 12.5 1.3 1 0 0 1 1 1 0 Outer membrane protein (OmpH-like) PBP_sp32 PF07222.7 EGC39627.1 - 0.27 10.3 19.9 0.39 9.8 13.8 1.2 1 0 0 1 1 1 0 Proacrosin binding protein sp32 DUF1510 PF07423.6 EGC39627.1 - 0.35 10.2 34.8 0.54 9.5 24.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Presenilin PF01080.12 EGC39627.1 - 0.38 9.5 15.7 0.63 8.7 10.9 1.3 1 0 0 1 1 1 0 Presenilin GAGA_bind PF06217.7 EGC39627.1 - 0.5 10.2 19.3 0.75 9.7 13.4 1.3 1 0 0 1 1 1 0 GAGA binding protein-like family RR_TM4-6 PF06459.7 EGC39627.1 - 1 9.1 23.6 1.5 8.6 16.4 1.1 1 0 0 1 1 1 0 Ryanodine Receptor TM 4-6 DHHW PF14286.1 EGC39627.1 - 1.2 8.4 19.6 0.22 10.7 11.0 1.6 1 1 0 1 1 1 0 DHHW protein DUF2201_N PF13203.1 EGC39627.1 - 1.2 8.1 7.6 2.1 7.4 5.3 1.4 1 0 0 1 1 1 0 Putative metallopeptidase domain Neur_chan_memb PF02932.11 EGC39627.1 - 2.6 7.8 8.7 3.8 7.3 6.0 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region SprA-related PF12118.3 EGC39627.1 - 2.9 7.1 29.2 3.8 6.7 20.2 1.1 1 0 0 1 1 1 0 SprA-related family OATP PF03137.15 EGC39627.1 - 3 5.7 8.1 7.3 4.5 5.6 1.6 1 1 0 1 1 1 0 Organic Anion Transporter Polypeptide (OATP) family Asp-B-Hydro_N PF05279.6 EGC39627.1 - 5.3 6.8 28.5 7.2 6.3 19.8 1.1 1 0 0 1 1 1 0 Aspartyl beta-hydroxylase N-terminal region CENP-T PF15511.1 EGC39627.1 - 8.1 5.5 16.0 12 5.0 11.1 1.1 1 0 0 1 1 1 0 Centromere kinetochore component CENP-T Ndc1_Nup PF09531.5 EGC39627.1 - 9.4 4.5 11.1 12 4.1 7.7 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup V_ATPase_I PF01496.14 EGC39627.1 - 9.5 3.9 20.7 13 3.4 14.3 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family EamA PF00892.15 EGC39628.1 - 1.8e-28 99.0 42.0 2.1e-15 56.8 9.6 2.8 3 0 0 3 3 3 2 EamA-like transporter family EmrE PF13536.1 EGC39628.1 - 3.8e-05 23.8 3.9 3.8e-05 23.8 2.7 4.0 2 2 2 4 4 4 1 Multidrug resistance efflux transporter DUF1129 PF06570.6 EGC39628.1 - 0.0039 16.5 1.9 0.0039 16.5 1.3 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF1129) UPF0546 PF10639.4 EGC39628.1 - 0.012 15.4 3.2 0.39 10.5 0.5 2.7 2 0 0 2 2 2 0 Uncharacterised protein family UPF0546 TPT PF03151.11 EGC39628.1 - 5.9 6.5 24.5 1.8 8.2 4.9 3.9 2 2 1 3 3 3 0 Triose-phosphate Transporter family Ldh_1_C PF02866.13 EGC39629.1 - 2.1e-39 135.0 0.0 3.2e-39 134.4 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, alpha/beta C-terminal domain Ldh_1_N PF00056.18 EGC39629.1 - 5.6e-29 100.7 0.0 8.5e-29 100.1 0.0 1.3 1 0 0 1 1 1 1 lactate/malate dehydrogenase, NAD binding domain DUF3439 PF11921.3 EGC39630.1 - 0.00072 19.2 5.0 0.00072 19.2 3.5 4.1 4 0 0 4 4 4 2 Domain of unknown function (DUF3439) zf-C3HC4_2 PF13923.1 EGC39630.1 - 0.49 10.4 10.5 1.2 9.1 7.3 1.8 1 0 0 1 1 1 0 Zinc finger, C3HC4 type (RING finger) Cnd1 PF12717.2 EGC39631.1 - 4.1e-50 170.0 36.5 1.5e-46 158.4 1.5 7.6 7 2 1 8 8 8 3 non-SMC mitotic condensation complex subunit 1 Adaptin_N PF01602.15 EGC39631.1 - 1.5e-12 46.6 14.3 7.3e-05 21.2 4.5 3.8 3 0 0 3 3 3 3 Adaptin N terminal region HEAT PF02985.17 EGC39631.1 - 6.9e-12 44.3 18.6 0.057 13.5 0.0 7.7 8 0 0 8 8 8 5 HEAT repeat HEAT_2 PF13646.1 EGC39631.1 - 3.1e-09 36.9 0.2 0.0014 18.8 0.0 4.3 3 1 1 4 4 4 3 HEAT repeats Cohesin_HEAT PF12765.2 EGC39631.1 - 2.5e-06 27.3 3.5 0.02 14.8 0.1 4.5 4 0 0 4 4 4 2 HEAT repeat associated with sister chromatid cohesion HEAT_EZ PF13513.1 EGC39631.1 - 3.5e-05 24.1 5.2 0.081 13.4 0.0 5.6 5 1 1 6 6 6 1 HEAT-like repeat AMP-binding PF00501.23 EGC39632.1 - 1.4e-75 254.3 0.0 1.7e-75 253.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC39632.1 - 2.9e-15 56.9 0.0 7.6e-15 55.6 0.0 1.7 1 0 0 1 1 1 1 AMP-binding enzyme C-terminal domain Sod_Cu PF00080.15 EGC39633.1 - 5.5e-47 159.4 7.9 6.3e-47 159.2 5.5 1.0 1 0 0 1 1 1 1 Copper/zinc superoxide dismutase (SODC) DUF2450 PF10475.4 EGC39635.1 - 2.1e-102 341.9 6.7 5.8e-102 340.5 4.6 1.8 1 0 0 1 1 1 1 Protein of unknown function N-terminal domain (DUF2450) DUF2451 PF10474.4 EGC39635.1 - 9.1e-67 225.2 0.2 9.1e-67 225.2 0.1 2.7 3 0 0 3 3 3 1 Protein of unknown function C-terminus (DUF2451) COG2 PF06148.6 EGC39635.1 - 0.0032 17.3 2.1 0.015 15.1 0.7 2.8 2 1 0 2 2 2 1 COG (conserved oligomeric Golgi) complex component, COG2 Sec8_exocyst PF04048.9 EGC39635.1 - 0.005 16.4 1.4 0.005 16.4 0.9 3.0 2 0 0 2 2 2 1 Sec8 exocyst complex component specific domain CDC73 PF05179.9 EGC39635.1 - 0.0073 15.6 8.0 0.3 10.3 5.5 2.4 1 1 0 1 1 1 1 RNA pol II accessory factor, Cdc73 family Vps54 PF07928.7 EGC39635.1 - 0.011 15.8 1.5 0.83 9.7 0.1 3.8 4 0 0 4 4 4 0 Vps54-like protein RP-C_C PF11800.3 EGC39635.1 - 0.59 9.8 8.1 18 4.9 5.0 2.6 2 0 0 2 2 2 0 Replication protein C C-terminal region Ribosomal_S10 PF00338.17 EGC39636.1 - 2.4e-28 97.8 0.8 3e-28 97.4 0.5 1.1 1 0 0 1 1 1 1 Ribosomal protein S10p/S20e DUF2418 PF10332.4 EGC39637.1 - 7.9e-18 64.6 1.6 7.9e-18 64.6 1.1 1.7 2 0 0 2 2 2 1 Protein of unknown function (DUF2418) AAA PF00004.24 EGC39638.1 - 6.2e-90 298.2 0.4 5.3e-45 152.8 0.0 3.0 3 0 0 3 3 2 2 ATPase family associated with various cellular activities (AAA) RuvB_N PF05496.7 EGC39638.1 - 3.7e-15 55.6 0.0 6.6e-07 28.6 0.0 2.8 2 1 0 2 2 2 2 Holliday junction DNA helicase ruvB N-terminus AAA_5 PF07728.9 EGC39638.1 - 2.7e-12 46.5 0.3 4.4e-06 26.4 0.1 4.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_2 PF07724.9 EGC39638.1 - 6.6e-10 39.1 0.1 0.00022 21.2 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) AAA_22 PF13401.1 EGC39638.1 - 2.3e-09 37.4 3.6 0.0013 18.8 0.1 4.7 3 2 1 4 4 3 2 AAA domain AAA_16 PF13191.1 EGC39638.1 - 1.8e-08 34.6 0.0 0.0049 16.8 0.0 2.8 2 1 0 2 2 2 2 AAA ATPase domain AAA_17 PF13207.1 EGC39638.1 - 3.6e-08 34.2 0.1 0.0041 17.9 0.0 3.4 2 1 0 2 2 2 2 AAA domain AAA_14 PF13173.1 EGC39638.1 - 4.3e-07 29.8 5.3 0.0027 17.5 0.0 4.2 4 0 0 4 4 3 2 AAA domain AAA_25 PF13481.1 EGC39638.1 - 9.9e-07 28.3 2.3 1.1 8.6 0.0 4.0 3 1 1 4 4 4 3 AAA domain CDC48_N PF02359.13 EGC39638.1 - 2.2e-06 27.4 0.1 8e-05 22.5 0.0 2.6 2 0 0 2 2 2 1 Cell division protein 48 (CDC48), N-terminal domain RNA_helicase PF00910.17 EGC39638.1 - 5.3e-06 26.5 1.2 0.31 11.2 0.0 4.0 4 0 0 4 4 3 2 RNA helicase IstB_IS21 PF01695.12 EGC39638.1 - 9.3e-06 25.1 0.0 0.15 11.4 0.0 2.4 2 0 0 2 2 2 2 IstB-like ATP binding protein AAA_33 PF13671.1 EGC39638.1 - 2.9e-05 23.9 0.3 0.15 11.9 0.0 2.9 3 0 0 3 3 2 2 AAA domain Mg_chelatase PF01078.16 EGC39638.1 - 3.9e-05 22.9 3.1 0.077 12.1 0.0 2.8 3 0 0 3 3 3 2 Magnesium chelatase, subunit ChlI Sigma54_activ_2 PF14532.1 EGC39638.1 - 6.2e-05 23.0 0.0 0.63 10.0 0.0 3.0 3 0 0 3 3 3 2 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGC39638.1 - 0.00013 21.1 0.0 0.23 10.5 0.0 2.4 2 0 0 2 2 2 2 Zeta toxin TIP49 PF06068.8 EGC39638.1 - 0.00021 20.1 7.1 0.086 11.5 0.0 3.6 4 0 0 4 4 3 2 TIP49 C-terminus AAA_28 PF13521.1 EGC39638.1 - 0.0005 20.0 0.0 1.1 9.2 0.0 2.4 2 0 0 2 2 2 2 AAA domain KaiC PF06745.8 EGC39638.1 - 0.00052 19.2 0.4 0.55 9.3 0.0 2.9 3 0 0 3 3 3 2 KaiC AAA_19 PF13245.1 EGC39638.1 - 0.00066 19.3 2.0 0.031 14.0 0.2 2.5 2 0 0 2 2 2 1 Part of AAA domain Sigma54_activat PF00158.21 EGC39638.1 - 0.00072 19.0 0.0 0.21 11.0 0.0 3.2 2 1 0 2 2 2 1 Sigma-54 interaction domain AAA_24 PF13479.1 EGC39638.1 - 0.00088 18.9 0.9 0.21 11.1 0.1 2.6 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGC39638.1 - 0.0022 17.6 0.0 1.7 8.2 0.0 2.5 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NACHT PF05729.7 EGC39638.1 - 0.017 14.7 0.5 5.2 6.7 0.0 3.5 4 0 0 4 4 4 0 NACHT domain AAA_18 PF13238.1 EGC39638.1 - 0.019 15.3 0.4 0.019 15.3 0.3 5.1 4 2 0 4 4 3 0 AAA domain PhoH PF02562.11 EGC39638.1 - 0.03 13.5 0.1 2.4 7.3 0.0 2.5 2 0 0 2 2 2 0 PhoH-like protein Vps4_C PF09336.5 EGC39638.1 - 0.042 13.7 0.0 8 6.4 0.0 2.8 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain SKI PF01202.17 EGC39638.1 - 0.044 13.6 0.0 11 5.8 0.0 2.8 2 0 0 2 2 2 0 Shikimate kinase ABC_tran PF00005.22 EGC39638.1 - 0.12 12.7 0.0 0.12 12.7 0.0 3.8 2 1 1 3 3 2 0 ABC transporter ubiquitin PF00240.18 EGC39639.1 - 1.1e-26 92.0 0.3 1.3e-26 91.7 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC39639.1 - 2.9e-14 52.5 0.1 3.1e-14 52.4 0.1 1.0 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC39639.1 - 0.00072 19.7 0.1 0.00072 19.7 0.0 1.1 1 0 0 1 1 1 1 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGC39639.1 - 0.0058 16.5 0.0 0.012 15.5 0.0 1.6 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC39639.1 - 0.011 15.9 0.0 0.012 15.7 0.0 1.1 1 0 0 1 1 1 0 DUF2407 ubiquitin-like domain Telomere_Sde2 PF13019.1 EGC39639.1 - 0.04 13.6 0.0 0.046 13.4 0.0 1.2 1 0 0 1 1 1 0 Telomere stability and silencing Phosphodiest PF01663.17 EGC39640.1 - 1.7e-12 47.4 0.2 5.3e-12 45.7 0.1 1.8 1 0 0 1 1 1 1 Type I phosphodiesterase / nucleotide pyrophosphatase TIG PF01833.19 EGC39640.1 - 1.2e-06 28.4 49.3 0.0002 21.3 1.2 7.2 6 1 1 7 7 7 4 IPT/TIG domain Ribosomal_L18p PF00861.17 EGC39640.1 - 0.42 10.8 0.1 1.3 9.2 0.0 1.7 2 0 0 2 2 2 0 Ribosomal L18p/L5e family Arf PF00025.16 EGC39641.1 - 1.9e-41 141.2 0.0 6.1e-41 139.5 0.0 1.8 1 1 0 1 1 1 1 ADP-ribosylation factor family Miro PF08477.8 EGC39641.1 - 1.1e-06 29.1 0.2 3.1e-06 27.6 0.0 1.9 2 0 0 2 2 2 1 Miro-like protein NACHT PF05729.7 EGC39641.1 - 0.00062 19.4 0.3 0.017 14.7 0.2 2.4 1 1 0 1 1 1 1 NACHT domain Ras PF00071.17 EGC39641.1 - 0.029 13.7 0.1 0.029 13.7 0.0 2.2 2 0 0 2 2 2 0 Ras family AAA_17 PF13207.1 EGC39641.1 - 0.037 14.8 0.7 0.19 12.5 0.0 2.4 2 1 1 3 3 3 0 AAA domain AAA_22 PF13401.1 EGC39641.1 - 0.039 14.1 0.1 0.22 11.6 0.0 2.1 2 0 0 2 2 2 0 AAA domain AAA PF00004.24 EGC39641.1 - 0.044 13.9 0.0 0.11 12.6 0.0 1.7 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) GAGA_bind PF06217.7 EGC39641.1 - 0.063 13.2 0.9 0.091 12.7 0.6 1.2 1 0 0 1 1 1 0 GAGA binding protein-like family AAA_24 PF13479.1 EGC39641.1 - 0.075 12.6 1.1 0.12 11.9 0.0 1.8 2 1 0 2 2 2 0 AAA domain SRP54 PF00448.17 EGC39641.1 - 0.08 12.3 0.1 0.16 11.4 0.0 1.5 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain SRPRB PF09439.5 EGC39641.1 - 0.082 12.1 0.1 0.082 12.1 0.1 2.3 2 1 0 2 2 2 0 Signal recognition particle receptor beta subunit DUF3010 PF11215.3 EGC39641.1 - 4.5 7.2 6.8 4.7 7.1 0.1 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3010) PAP_assoc PF03828.14 EGC39642.1 - 8.4e-19 67.2 0.4 2.2e-18 65.9 0.2 1.8 2 0 0 2 2 2 1 Cid1 family poly A polymerase RCC1 PF00415.13 EGC39643.1 - 1.9e-33 114.4 0.0 8.4e-12 45.1 0.0 6.7 6 1 0 6 6 6 5 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC39643.1 - 1.3e-23 81.9 1.2 2.8e-09 36.3 0.0 6.1 7 0 0 7 7 7 5 Regulator of chromosome condensation (RCC1) repeat Sorb PF02208.11 EGC39644.1 - 0.12 11.7 0.0 0.21 11.0 0.0 1.4 1 0 0 1 1 1 0 Sorbin homologous domain DUF2953 PF11167.3 EGC39645.1 - 0.079 12.8 0.1 0.11 12.4 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2953) RCC1 PF00415.13 EGC39646.1 - 4.8e-72 238.0 15.0 7e-14 51.7 0.1 7.8 7 1 0 7 7 7 7 Regulator of chromosome condensation (RCC1) repeat RCC1_2 PF13540.1 EGC39646.1 - 1.2e-35 120.2 28.8 9.1e-09 34.7 1.1 6.6 6 0 0 6 6 6 6 Regulator of chromosome condensation (RCC1) repeat DUF4213 PF13938.1 EGC39646.1 - 0.0083 16.2 0.1 1.2 9.2 0.0 2.7 2 0 0 2 2 2 1 Domain of unknown function (DUF4213) DUF2194 PF09960.4 EGC39647.1 - 0.0048 15.0 0.5 0.0049 14.9 0.3 1.0 1 0 0 1 1 1 1 Uncharacterized protein conserved in bacteria (DUF2194) p450 PF00067.17 EGC39648.1 - 6.9e-98 328.1 0.0 7.9e-98 327.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUF1049 PF06305.6 EGC39649.1 - 0.12 11.8 0.1 0.17 11.3 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1049) Amastin PF07344.6 EGC39650.1 - 0.56 9.7 12.3 0.016 14.8 3.1 2.0 1 1 1 2 2 2 0 Amastin surface glycoprotein Pox_A28 PF04584.9 EGC39650.1 - 0.64 9.8 3.7 0.46 10.3 1.3 1.7 2 0 0 2 2 2 0 Poxvirus A28 family Amastin PF07344.6 EGC39651.1 - 0.41 10.2 7.0 0.28 10.7 2.9 1.9 2 0 0 2 2 2 0 Amastin surface glycoprotein Glyco_hydro_38 PF01074.17 EGC39652.1 - 1.4e-72 244.2 6.7 2.6e-72 243.3 4.7 1.5 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC39652.1 - 1.2e-17 63.8 1.3 3.5e-17 62.3 0.0 2.6 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Glyco_hydro_38 PF01074.17 EGC39653.1 - 9.5e-67 225.1 6.8 9.5e-67 225.1 4.7 2.0 2 0 0 2 2 2 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC39653.1 - 2.2e-19 69.4 0.7 9.1e-19 67.4 0.5 2.2 1 0 0 1 1 1 1 Alpha mannosidase, middle domain Glyco_hydro_38 PF01074.17 EGC39654.1 - 2.6e-54 184.3 0.3 4.3e-54 183.6 0.2 1.4 1 0 0 1 1 1 1 Glycosyl hydrolases family 38 N-terminal domain Alpha-mann_mid PF09261.6 EGC39654.1 - 6.6e-16 58.3 1.2 2.7e-15 56.3 0.1 2.6 2 0 0 2 2 2 1 Alpha mannosidase, middle domain Myotub-related PF06602.9 EGC39655.1 - 1.8e-129 431.5 0.0 4.2e-129 430.3 0.0 1.7 1 0 0 1 1 1 1 Myotubularin-like phosphatase domain GRAM PF02893.15 EGC39655.1 - 0.00022 20.6 0.1 0.00085 18.7 0.0 2.1 1 0 0 1 1 1 1 GRAM domain Y_phosphatase3 PF13350.1 EGC39655.1 - 0.0044 17.3 0.0 0.019 15.1 0.0 2.1 2 0 0 2 2 2 1 Tyrosine phosphatase family YqfQ PF14181.1 EGC39655.1 - 0.59 10.1 10.9 0.65 10.0 5.9 2.3 1 1 0 1 1 1 0 YqfQ-like protein Pex14_N PF04695.8 EGC39655.1 - 7.5 6.6 17.5 0.89 9.6 1.2 2.8 3 0 0 3 3 3 0 Peroxisomal membrane anchor protein (Pex14p) conserved region Phospholip_B PF04916.8 EGC39656.1 - 1.5e-118 396.3 8.9 1.9e-118 396.0 6.2 1.0 1 0 0 1 1 1 1 Phospholipase B FNIP PF05725.7 EGC39657.1 - 1.6e-181 588.1 43.3 6.1e-14 51.6 0.0 14.6 8 2 5 16 16 16 16 FNIP Repeat DUF1769 PF08588.5 EGC39657.1 - 0.016 15.1 47.2 9.5 6.2 0.1 15.8 7 5 11 18 18 18 0 Protein of unknown function (DUF1769) Terminase_1 PF03354.10 EGC39657.1 - 0.21 9.9 0.1 0.31 9.4 0.1 1.1 1 0 0 1 1 1 0 Phage Terminase DUF1662 PF07878.6 EGC39657.1 - 2.8 7.7 13.9 1.1e+02 2.5 0.0 8.7 11 0 0 11 11 11 0 Protein of unknown function (DUF1662) Dimer_Tnp_hAT PF05699.9 EGC39658.1 - 0.0023 17.4 0.1 0.0046 16.5 0.0 1.5 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region ArfGap PF01412.13 EGC39658.1 - 0.13 12.0 1.7 0.17 11.6 1.2 1.2 1 0 0 1 1 1 0 Putative GTPase activating protein for Arf CutA1 PF03091.10 EGC39659.1 - 0.048 13.3 0.0 0.17 11.5 0.0 2.0 1 0 0 1 1 1 0 CutA1 divalent ion tolerance protein tRNA_SAD PF07973.9 EGC39660.1 - 1.5e-05 24.7 0.0 3.3e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Threonyl and Alanyl tRNA synthetase second additional domain Lactamase_B_2 PF12706.2 EGC39660.1 - 0.12 11.9 0.0 0.18 11.3 0.0 1.3 1 0 0 1 1 1 0 Beta-lactamase superfamily domain N6-adenineMlase PF10237.4 EGC39661.1 - 1e-54 184.5 0.9 1.2e-54 184.3 0.6 1.1 1 0 0 1 1 1 1 Probable N6-adenine methyltransferase Cons_hypoth95 PF03602.10 EGC39661.1 - 0.021 14.2 0.0 0.032 13.6 0.0 1.3 1 1 0 1 1 1 0 Conserved hypothetical protein 95 MARVEL PF01284.18 EGC39664.1 - 0.01 15.6 17.3 1.4 8.6 4.7 3.8 1 1 1 2 2 2 0 Membrane-associating domain DUF3619 PF12279.3 EGC39664.1 - 0.12 12.4 0.2 0.12 12.4 0.1 3.7 2 1 2 4 4 4 0 Protein of unknown function (DUF3619) DUF898 PF05987.8 EGC39664.1 - 0.2 10.5 4.9 1.2 7.9 3.4 2.4 1 1 0 1 1 1 0 Bacterial protein of unknown function (DUF898) Metal_resist PF13801.1 EGC39664.1 - 0.49 10.3 4.7 4.3 7.3 0.5 2.6 3 0 0 3 3 3 0 Heavy-metal resistance DUF1275 PF06912.6 EGC39664.1 - 1.8 7.6 18.9 0.85 8.7 3.0 3.9 1 1 1 3 3 3 0 Protein of unknown function (DUF1275) DUF3357 PF11837.3 EGC39664.1 - 7.2 6.5 18.8 1.8 8.4 0.0 5.5 1 1 6 7 7 7 0 Domain of unknown function (DUF3357) Actin PF00022.14 EGC39665.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC39665.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) DUF2407_C PF13373.1 EGC39667.1 - 0.088 12.7 0.0 0.25 11.2 0.0 1.7 1 0 0 1 1 1 0 DUF2407 C-terminal domain EGF_2 PF07974.8 EGC39667.1 - 0.2 11.8 16.0 0.022 14.9 7.7 1.9 2 0 0 2 2 2 0 EGF-like domain PolyA_pol PF01743.15 EGC39669.1 - 1.5e-21 76.8 0.1 3.9e-21 75.5 0.1 1.7 1 0 0 1 1 1 1 Poly A polymerase head domain PolyA_pol_RNAbd PF12627.2 EGC39669.1 - 5.4e-07 29.0 0.1 2.2e-06 27.1 0.0 2.1 2 0 0 2 2 2 1 Probable RNA and SrmB- binding site of polymerase A Pkinase PF00069.20 EGC39670.1 - 6.7e-39 133.6 1.1 1.5e-37 129.1 0.8 2.1 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39670.1 - 1.5e-20 73.3 0.1 3.7e-20 72.1 0.1 1.7 1 1 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.7 EGC39670.1 - 2.5e-17 62.5 27.6 3.8e-09 36.3 0.1 5.7 4 1 1 5 5 5 3 FNIP Repeat Kinase-like PF14531.1 EGC39670.1 - 0.0014 17.6 0.0 0.0022 17.0 0.0 1.2 1 0 0 1 1 1 1 Kinase-like DUF2724 PF10893.3 EGC39670.1 - 0.07 13.0 0.0 0.13 12.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2724) SICA_beta PF12878.2 EGC39670.1 - 0.088 12.5 0.0 0.14 11.9 0.0 1.2 1 0 0 1 1 1 0 SICA extracellular beta domain APH PF01636.18 EGC39670.1 - 0.22 11.1 0.0 0.33 10.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family BRCT PF00533.21 EGC39671.1 - 9.3e-20 70.5 3.5 1.6e-09 37.7 0.1 3.0 2 0 0 2 2 2 2 BRCA1 C Terminus (BRCT) domain FHA PF00498.21 EGC39671.1 - 9.9e-11 41.6 0.1 3.2e-10 39.9 0.1 2.0 1 0 0 1 1 1 1 FHA domain PTCB-BRCT PF12738.2 EGC39671.1 - 2.5e-06 27.2 0.0 0.0004 20.1 0.0 2.5 2 0 0 2 2 2 2 twin BRCT domain XRN_N PF03159.13 EGC39673.1 - 2e-27 96.1 1.1 2.5e-27 95.8 0.8 1.1 1 0 0 1 1 1 1 XRN 5'-3' exonuclease N-terminus XPG_N PF00752.12 EGC39673.1 - 0.00013 22.1 0.1 0.00026 21.2 0.1 1.4 1 0 0 1 1 1 1 XPG N-terminal domain XPG_I PF00867.13 EGC39673.1 - 0.022 14.8 0.2 0.063 13.3 0.1 1.8 1 0 0 1 1 1 0 XPG I-region Glyco_hydro_43 PF04616.9 EGC39673.1 - 0.044 12.8 0.6 0.25 10.4 0.0 2.1 2 0 0 2 2 2 0 Glycosyl hydrolases family 43 Tachylectin PF14517.1 EGC39673.1 - 0.062 12.6 0.1 0.14 11.4 0.0 1.5 1 0 0 1 1 1 0 Tachylectin Glyco_hydro_88 PF07470.8 EGC39673.1 - 0.092 11.7 0.1 0.13 11.2 0.1 1.2 1 0 0 1 1 1 0 Glycosyl Hydrolase Family 88 ketoacyl-synt PF00109.21 EGC39674.1 - 1.6e-45 155.6 0.0 2e-45 155.2 0.0 1.0 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Thiolase_N PF00108.18 EGC39674.1 - 5.4e-05 22.2 0.1 0.0001 21.3 0.1 1.4 1 1 0 1 1 1 1 Thiolase, N-terminal domain Acyl_transf_1 PF00698.16 EGC39675.1 - 6.7e-45 153.7 0.0 1.3e-43 149.5 0.0 2.3 2 0 0 2 2 2 1 Acyl transferase domain Methyltransf_12 PF08242.7 EGC39675.1 - 4.6e-17 62.3 0.2 4e-16 59.2 0.0 2.9 2 0 0 2 2 1 1 Methyltransferase domain KR PF08659.5 EGC39675.1 - 2.1e-15 56.8 0.0 3.9e-15 55.9 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC39675.1 - 2.1e-10 40.7 0.0 7.3e-10 39.0 0.0 2.0 2 0 0 2 2 2 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC39675.1 - 1.1e-09 39.2 0.0 2.3e-09 38.2 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Methyltransf_11 PF08241.7 EGC39675.1 - 8e-09 35.8 0.0 6.5e-08 32.9 0.0 2.6 2 0 0 2 2 2 1 Methyltransferase domain ADH_N PF08240.7 EGC39675.1 - 8.4e-09 35.1 0.0 2.1e-08 33.9 0.0 1.7 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain PS-DH PF14765.1 EGC39675.1 - 6e-08 32.1 0.0 8.9e-08 31.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Methyltransf_31 PF13847.1 EGC39675.1 - 2e-06 27.4 0.1 2e-06 27.4 0.1 3.4 3 0 0 3 3 3 1 Methyltransferase domain ADH_zinc_N PF00107.21 EGC39675.1 - 3.3e-06 26.6 0.0 6.6e-06 25.7 0.0 1.5 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Ubie_methyltran PF01209.13 EGC39675.1 - 9.2e-05 21.6 0.0 0.00032 19.8 0.0 1.9 2 0 0 2 2 2 1 ubiE/COQ5 methyltransferase family Methyltransf_23 PF13489.1 EGC39675.1 - 0.00017 21.3 0.1 0.0009 18.9 0.0 2.1 2 0 0 2 2 2 1 Methyltransferase domain PP-binding PF00550.20 EGC39675.1 - 0.0036 17.5 0.1 0.0099 16.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site BTB PF00651.26 EGC39676.1 - 7.1e-25 87.1 0.0 6.1e-23 80.9 0.0 2.7 1 1 1 2 2 2 1 BTB/POZ domain BACK PF07707.10 EGC39676.1 - 0.014 15.2 0.1 0.13 12.1 0.0 2.5 2 0 0 2 2 2 0 BTB And C-terminal Kelch HEAT PF02985.17 EGC39676.1 - 0.02 14.9 0.0 1.9 8.7 0.0 3.0 2 0 0 2 2 2 0 HEAT repeat Arm PF00514.18 EGC39676.1 - 0.099 12.4 0.6 16 5.4 0.3 4.2 4 0 0 4 4 4 0 Armadillo/beta-catenin-like repeat GTP_cyclohydroI PF01227.17 EGC39677.1 - 0.064 12.5 0.1 0.11 11.7 0.1 1.3 1 1 0 1 1 1 0 GTP cyclohydrolase I DUF1938 PF09153.5 EGC39677.1 - 0.19 11.5 1.3 0.73 9.6 0.1 2.0 1 1 1 2 2 2 0 Domain of unknown function (DUF1938) TIG PF01833.19 EGC39678.1 - 2e-32 110.9 80.0 2.5e-12 46.6 1.5 10.4 8 1 1 9 9 9 9 IPT/TIG domain EGF_2 PF07974.8 EGC39678.1 - 0.00037 20.5 11.8 0.00037 20.5 8.1 1.9 2 0 0 2 2 2 1 EGF-like domain Laminin_EGF PF00053.19 EGC39678.1 - 0.26 11.2 8.9 0.7 9.8 6.2 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF_CA PF07645.10 EGC39678.1 - 0.31 11.0 8.9 1.1 9.2 6.1 2.0 1 0 0 1 1 1 0 Calcium-binding EGF domain Ras PF00071.17 EGC39680.1 - 7.3e-47 158.7 0.5 8.8e-47 158.4 0.3 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39680.1 - 5.3e-18 65.6 0.2 9.2e-18 64.8 0.1 1.4 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39680.1 - 2.1e-08 33.5 0.0 2.5e-08 33.3 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC39680.1 - 1.7e-06 27.5 0.2 4.3e-06 26.2 0.1 1.7 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC39680.1 - 7.4e-05 22.6 0.1 0.00012 22.0 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase PKD_channel PF08016.7 EGC39681.1 - 2.3e-44 151.5 14.4 2.3e-44 151.5 9.9 1.4 2 0 0 2 2 2 1 Polycystin cation channel Ion_trans PF00520.26 EGC39681.1 - 0.0013 18.0 27.1 0.0013 18.0 18.8 3.0 2 1 1 3 3 3 1 Ion transport protein Baculo_11_kDa PF06143.6 EGC39681.1 - 0.018 14.3 5.4 0.81 9.0 0.1 3.2 3 0 0 3 3 3 0 Baculovirus 11 kDa family FUSC PF04632.7 EGC39681.1 - 0.1 11.0 7.8 0.17 10.2 5.4 1.3 1 0 0 1 1 1 0 Fusaric acid resistance protein family DUF3430 PF11912.3 EGC39682.1 - 9 6.0 13.5 33 4.2 9.4 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF3430) PhyH PF05721.8 EGC39683.1 - 6e-12 46.0 0.0 4.6e-09 36.6 0.0 2.4 2 1 0 2 2 2 2 Phytanoyl-CoA dioxygenase (PhyH) DUF1479 PF07350.7 EGC39683.1 - 7.5e-05 21.3 0.0 0.0054 15.2 0.0 2.4 3 0 0 3 3 3 2 Protein of unknown function (DUF1479) 2OG-FeII_Oxy_5 PF13759.1 EGC39683.1 - 0.0038 17.4 0.2 0.019 15.2 0.0 2.2 2 0 0 2 2 2 1 Putative 2OG-Fe(II) oxygenase ADP_PFK_GK PF04587.10 EGC39683.1 - 0.14 10.2 0.1 0.24 9.5 0.0 1.2 1 0 0 1 1 1 0 ADP-specific Phosphofructokinase/Glucokinase conserved region Fra10Ac1 PF09725.4 EGC39684.1 - 1.2e-45 154.4 1.2 1.2e-45 154.4 0.8 2.8 2 1 1 3 3 3 1 Folate-sensitive fragile site protein Fra10Ac1 Serinc PF03348.10 EGC39684.1 - 0.37 9.4 4.3 0.63 8.6 3.0 1.4 1 0 0 1 1 1 0 Serine incorporator (Serinc) DUF2215 PF10225.4 EGC39684.1 - 0.38 10.1 3.1 0.13 11.6 0.3 1.6 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Atrophin-1 PF03154.10 EGC39684.1 - 1.3 7.0 10.2 1.8 6.6 7.1 1.2 1 0 0 1 1 1 0 Atrophin-1 family Nucleoside_tran PF01733.13 EGC39684.1 - 4.1 6.4 4.2 11 5.0 2.9 1.8 1 1 0 1 1 1 0 Nucleoside transporter Rtf2 PF04641.7 EGC39684.1 - 9.3 5.3 26.9 0.14 11.3 12.1 2.0 2 0 0 2 2 2 0 Rtf2 RING-finger Protocadherin PF08374.6 EGC39684.1 - 9.4 5.8 24.8 2.8 7.5 8.0 2.3 2 0 0 2 2 2 0 Protocadherin Acetyltransf_3 PF13302.1 EGC39685.1 - 1.5e-25 90.0 0.5 1.8e-25 89.7 0.3 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC39685.1 - 3.8e-08 33.4 4.6 1.4e-07 31.6 3.2 1.8 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC39685.1 - 2.2e-07 30.8 0.3 6.6e-07 29.3 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC39685.1 - 4.7e-07 29.7 0.0 6.1e-07 29.3 0.0 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family FR47 PF08445.5 EGC39685.1 - 3.9e-06 26.5 0.1 6.4e-06 25.8 0.0 1.3 1 0 0 1 1 1 1 FR47-like protein Acetyltransf_7 PF13508.1 EGC39685.1 - 0.01 16.0 0.1 0.017 15.2 0.0 1.5 1 1 0 1 1 1 0 Acetyltransferase (GNAT) domain ATG2_CAD PF13329.1 EGC39685.1 - 0.041 13.4 0.1 0.06 12.9 0.0 1.3 1 0 0 1 1 1 0 Autophagy-related protein 2 CAD motif RhoGAP PF00620.22 EGC39687.1 - 1.3e-38 132.0 0.2 3.3e-38 130.7 0.1 1.7 1 0 0 1 1 1 1 RhoGAP domain Upf2 PF04050.9 EGC39687.1 - 3.8 7.2 16.6 2.6 7.7 0.8 2.5 1 1 1 2 2 2 0 Up-frameshift suppressor 2 PH PF00169.24 EGC39688.1 - 1.7e-20 73.1 0.8 1.7e-20 73.1 0.6 2.8 2 1 0 2 2 2 1 PH domain PH_11 PF15413.1 EGC39688.1 - 2.1e-06 27.9 1.1 2.1e-06 27.9 0.8 3.1 3 1 0 3 3 3 1 Pleckstrin homology domain PH_3 PF14593.1 EGC39688.1 - 5.9e-05 22.9 0.5 5.9e-05 22.9 0.3 2.0 2 0 0 2 2 2 1 PH domain PH_9 PF15410.1 EGC39688.1 - 0.0025 17.9 1.3 0.036 14.2 0.1 2.8 2 2 0 2 2 2 1 Pleckstrin homology domain PH_8 PF15409.1 EGC39688.1 - 0.03 14.4 0.1 0.085 12.9 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain PH_6 PF15406.1 EGC39688.1 - 0.047 13.7 0.0 0.11 12.5 0.0 1.6 1 0 0 1 1 1 0 Pleckstrin homology domain VP7 PF00434.13 EGC39688.1 - 0.12 11.2 0.0 0.12 11.2 0.0 1.6 2 0 0 2 2 2 0 Glycoprotein VP7 N6_N4_Mtase PF01555.13 EGC39688.1 - 0.16 11.4 4.6 0.06 12.8 1.5 1.5 2 0 0 2 2 2 0 DNA methylase PAP_central PF04928.12 EGC39688.1 - 0.4 9.4 4.2 0.58 8.9 2.9 1.3 1 0 0 1 1 1 0 Poly(A) polymerase central domain CemA PF03040.9 EGC39688.1 - 0.46 10.0 4.6 0.7 9.4 3.2 1.3 1 0 0 1 1 1 0 CemA family Mcp5_PH PF12814.2 EGC39688.1 - 0.97 9.3 6.4 0.71 9.7 0.0 2.9 2 1 2 4 4 4 0 Meiotic cell cortex C-terminal pleckstrin homology Mst1_SARAH PF11629.3 EGC39688.1 - 1.2 9.0 9.9 0.85 9.4 1.5 2.5 1 1 1 2 2 2 0 C terminal SARAH domain of Mst1 FNIP PF05725.7 EGC39690.1 - 2.6e-108 353.7 78.2 1.6e-15 56.7 0.1 14.8 7 3 9 18 18 18 16 FNIP Repeat LRR_5 PF13306.1 EGC39690.1 - 0.0045 16.6 16.5 0.33 10.6 0.1 5.8 1 1 7 8 8 8 5 Leucine rich repeats (6 copies) Pkinase PF00069.20 EGC39691.1 - 9.2e-42 142.9 0.1 1.5e-41 142.2 0.1 1.3 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39691.1 - 3.6e-20 72.1 0.0 2.5e-19 69.3 0.0 2.1 1 1 0 1 1 1 1 Protein tyrosine kinase FNIP PF05725.7 EGC39691.1 - 1.4e-19 69.7 40.5 9.7e-08 31.8 0.7 5.4 2 1 4 6 6 6 5 FNIP Repeat Kinase-like PF14531.1 EGC39691.1 - 0.0009 18.2 0.0 0.0014 17.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like Choline_kinase PF01633.15 EGC39691.1 - 0.0021 17.6 0.4 0.005 16.4 0.3 1.6 1 0 0 1 1 1 1 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EGC39691.1 - 0.011 15.1 0.2 0.032 13.5 0.0 1.8 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL APH PF01636.18 EGC39691.1 - 0.011 15.4 0.0 0.016 14.9 0.0 1.1 1 0 0 1 1 1 0 Phosphotransferase enzyme family DUF2779 PF11074.3 EGC39691.1 - 0.04 13.9 0.6 0.1 12.6 0.4 1.7 1 0 0 1 1 1 0 Domain of unknown function(DUF2779) Proteasome PF00227.21 EGC39692.1 - 1.8e-27 95.8 0.0 2.4e-27 95.4 0.0 1.0 1 0 0 1 1 1 1 Proteasome subunit DUF2369 PF10179.4 EGC39693.1 - 0.023 13.8 0.0 0.034 13.2 0.0 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2369) Homeobox_KN PF05920.6 EGC39695.1 - 3.8e-18 64.8 0.7 5.4e-18 64.4 0.5 1.2 1 0 0 1 1 1 1 Homeobox KN domain Homeobox PF00046.24 EGC39695.1 - 1.2e-08 34.4 0.1 1.3e-08 34.2 0.1 1.1 1 0 0 1 1 1 1 Homeobox domain HTH_3 PF01381.17 EGC39695.1 - 0.027 14.2 0.0 0.049 13.4 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix Proteasome PF00227.21 EGC39696.1 - 5.1e-35 120.4 0.2 6.1e-35 120.2 0.2 1.1 1 0 0 1 1 1 1 Proteasome subunit Pkinase PF00069.20 EGC39697.1 - 2.6e-38 131.6 3.6 1.1e-36 126.3 1.1 2.9 2 1 0 2 2 2 1 Protein kinase domain FNIP PF05725.7 EGC39697.1 - 4.6e-18 64.8 21.3 1.4e-11 44.1 1.8 7.9 7 1 2 9 9 9 4 FNIP Repeat Pkinase_Tyr PF07714.12 EGC39697.1 - 9.6e-18 64.1 0.1 3e-16 59.2 0.1 2.3 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC39697.1 - 0.19 11.4 0.0 0.29 10.8 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family Pkinase PF00069.20 EGC39698.1 - 0.00027 20.1 0.4 0.00057 19.1 0.1 1.6 2 0 0 2 2 2 1 Protein kinase domain FNIP PF05725.7 EGC39698.1 - 0.00094 19.0 2.5 0.052 13.4 0.1 4.8 3 1 3 6 6 6 3 FNIP Repeat DUF2414 PF10309.4 EGC39698.1 - 0.026 14.2 0.2 4.3 7.0 0.0 2.5 2 0 0 2 2 2 0 Protein of unknown function (DUF2414) FDX-ACB PF03147.9 EGC39698.1 - 0.073 13.2 0.0 0.17 12.0 0.0 1.6 1 0 0 1 1 1 0 Ferredoxin-fold anticodon binding domain Pkinase PF00069.20 EGC39699.1 - 4.8e-116 386.4 24.6 8.8e-50 169.2 3.9 5.6 3 3 0 3 3 3 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39699.1 - 2.5e-57 193.8 10.5 5.4e-23 81.3 1.5 5.1 3 3 0 3 3 3 3 Protein tyrosine kinase FNIP PF05725.7 EGC39699.1 - 1.6e-41 140.0 106.9 4.1e-11 42.6 1.8 14.1 12 2 3 15 15 15 10 FNIP Repeat Kdo PF06293.9 EGC39699.1 - 2.1e-13 49.8 0.1 6.1e-05 22.1 0.0 3.3 3 0 0 3 3 3 3 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC39699.1 - 0.00011 21.3 0.0 0.24 10.3 0.0 2.9 3 0 0 3 3 3 2 Kinase-like APH PF01636.18 EGC39699.1 - 0.00032 20.5 0.1 0.54 9.9 0.3 3.5 3 1 1 4 4 4 1 Phosphotransferase enzyme family DUF2087 PF09860.4 EGC39699.1 - 0.096 12.4 0.6 2.2 8.0 0.0 2.9 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2087) FNIP PF05725.7 EGC39700.1 - 1.5e-41 140.1 9.5 1.2e-15 57.1 0.1 3.3 2 1 1 4 4 4 3 FNIP Repeat EIID-AGA PF03613.9 EGC39700.1 - 0.1 11.5 0.1 0.12 11.3 0.0 1.0 1 0 0 1 1 1 0 PTS system mannose/fructose/sorbose family IID component DUF1662 PF07878.6 EGC39700.1 - 0.13 12.0 0.1 55 3.6 0.0 3.5 4 0 0 4 4 4 0 Protein of unknown function (DUF1662) FNIP PF05725.7 EGC39701.1 - 2.4e-126 411.4 35.2 7e-15 54.7 0.0 6.7 1 1 8 10 10 10 10 FNIP Repeat Shigella_OspC PF06128.6 EGC39701.1 - 0.35 10.3 3.1 25 4.2 0.1 3.2 2 1 0 3 3 3 0 Shigella flexneri OspC protein F-box-like PF12937.2 EGC39702.1 - 0.064 12.9 0.8 0.53 10.0 0.1 2.5 2 0 0 2 2 2 0 F-box-like Macoilin PF09726.4 EGC39703.1 - 1.1 7.4 7.9 1.3 7.2 5.5 1.2 1 0 0 1 1 1 0 Transmembrane protein L51_S25_CI-B8 PF05047.11 EGC39704.1 - 1.8e-10 40.4 0.0 3.3e-10 39.5 0.0 1.4 1 0 0 1 1 1 1 Mitochondrial ribosomal protein L51 / S25 / CI-B8 domain zf-RING_2 PF13639.1 EGC39706.1 - 1.5e-09 37.5 8.7 2.8e-09 36.6 6.1 1.5 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39706.1 - 2.3e-08 33.5 7.4 4.1e-08 32.7 5.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39706.1 - 1.1e-06 28.1 11.1 1.1e-06 28.1 7.7 1.9 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39706.1 - 5.6e-06 26.2 10.1 1.3e-05 25.1 7.0 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39706.1 - 0.00015 21.3 8.7 0.00015 21.3 6.1 1.9 2 0 0 2 2 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39706.1 - 0.00031 20.2 9.5 0.00075 19.0 6.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-rbx1 PF12678.2 EGC39706.1 - 0.00064 19.7 6.0 0.0018 18.3 4.1 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC39706.1 - 0.0024 17.7 8.6 0.0099 15.7 6.0 2.1 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-MIZ PF02891.15 EGC39706.1 - 0.0084 15.5 7.7 0.017 14.6 5.3 1.5 1 0 0 1 1 1 1 MIZ/SP-RING zinc finger zf-RING_6 PF14835.1 EGC39706.1 - 0.017 14.8 1.8 0.044 13.5 1.2 1.7 1 0 0 1 1 1 0 zf-RING of BARD1-type protein zf-RING_UBOX PF13445.1 EGC39706.1 - 0.047 13.4 7.0 0.28 10.9 4.8 2.4 1 0 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC39706.1 - 0.12 12.2 1.5 0.25 11.2 1.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger DZR PF12773.2 EGC39706.1 - 2.9 7.7 8.1 20 5.0 5.5 2.3 1 1 0 1 1 1 0 Double zinc ribbon EGF_2 PF07974.8 EGC39708.1 - 7.2e-06 26.0 7.5 1.4e-05 25.1 5.2 1.5 1 0 0 1 1 1 1 EGF-like domain Laminin_EGF PF00053.19 EGC39708.1 - 0.00075 19.3 7.8 0.0013 18.6 5.4 1.4 1 0 0 1 1 1 1 Laminin EGF-like (Domains III and V) EGF_alliinase PF04863.8 EGC39708.1 - 0.021 14.7 5.0 0.042 13.8 3.4 1.5 1 0 0 1 1 1 0 Alliinase EGF-like domain zf-C2H2_jaz PF12171.3 EGC39709.1 - 2e-08 34.1 2.7 2e-08 34.1 1.8 2.9 3 0 0 3 3 3 1 Zinc-finger double-stranded RNA-binding zf-met PF12874.2 EGC39709.1 - 3.3e-06 27.1 5.5 1.2e-05 25.3 1.6 2.7 2 0 0 2 2 2 1 Zinc-finger of C2H2 type zf-C2H2_2 PF12756.2 EGC39709.1 - 0.0024 17.9 3.0 0.003 17.6 0.2 2.6 2 0 0 2 2 2 1 C2H2 type zinc-finger (2 copies) zf-C2H2_4 PF13894.1 EGC39709.1 - 0.033 14.5 2.4 0.033 14.5 1.6 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-C2H2_6 PF13912.1 EGC39709.1 - 0.086 12.7 0.5 0.086 12.7 0.3 2.1 2 0 0 2 2 2 0 C2H2-type zinc finger zf-Di19 PF05605.7 EGC39709.1 - 0.15 12.2 0.2 0.32 11.1 0.1 1.5 1 0 0 1 1 1 0 Drought induced 19 protein (Di19), zinc-binding Equine_IAV_S2 PF06502.6 EGC39709.1 - 0.26 11.1 6.6 0.7 9.7 0.6 3.3 2 0 0 2 2 2 0 Equine infectious anaemia virus S2 protein RasGAP PF00616.14 EGC39710.1 - 3.2e-47 160.7 0.1 3.2e-47 160.7 0.1 3.5 3 0 0 3 3 3 2 GTPase-activator protein for Ras-like GTPase Bromodomain PF00439.20 EGC39711.1 - 7.3e-21 73.8 0.1 1.4e-20 73.0 0.1 1.5 1 0 0 1 1 1 1 Bromodomain Acetyltransf_7 PF13508.1 EGC39711.1 - 4.2e-11 42.8 3.1 6.9e-11 42.1 0.5 2.2 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC39711.1 - 4.7e-09 36.1 0.0 1.1e-08 35.0 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DYW_deaminase PF14432.1 EGC39711.1 - 0.011 15.6 0.0 0.021 14.7 0.0 1.5 1 0 0 1 1 1 0 DYW family of nucleic acid deaminases Arf PF00025.16 EGC39712.1 - 4.8e-46 156.1 0.1 5.8e-46 155.9 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Ras PF00071.17 EGC39712.1 - 1.2e-20 73.5 0.0 1.4e-20 73.2 0.0 1.1 1 0 0 1 1 1 1 Ras family Gtr1_RagA PF04670.7 EGC39712.1 - 6.8e-12 45.0 0.0 7.7e-12 44.8 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region Miro PF08477.8 EGC39712.1 - 2.6e-11 44.0 0.0 4.2e-11 43.3 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein G-alpha PF00503.15 EGC39712.1 - 2.1e-09 36.5 0.4 3.7e-07 29.1 0.0 2.2 1 1 1 2 2 2 2 G-protein alpha subunit SRPRB PF09439.5 EGC39712.1 - 2.5e-08 33.3 0.0 3.3e-08 32.9 0.0 1.1 1 0 0 1 1 1 1 Signal recognition particle receptor beta subunit MMR_HSR1 PF01926.18 EGC39712.1 - 3.5e-08 33.4 0.0 5.2e-08 32.8 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU PF00009.22 EGC39712.1 - 1.8e-05 24.2 0.1 0.00032 20.1 0.1 2.0 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain NACHT PF05729.7 EGC39712.1 - 0.00095 18.8 0.0 0.62 9.6 0.0 2.1 2 0 0 2 2 2 2 NACHT domain ATP_bind_1 PF03029.12 EGC39712.1 - 0.0018 17.8 0.2 1.5 8.2 0.1 2.2 1 1 1 2 2 2 2 Conserved hypothetical ATP binding protein ABC_tran PF00005.22 EGC39712.1 - 0.0046 17.2 0.5 0.0052 17.0 0.3 1.4 1 1 0 1 1 1 1 ABC transporter cobW PF02492.14 EGC39712.1 - 0.0065 15.9 2.5 0.2 11.0 0.1 2.3 2 1 0 2 2 2 1 CobW/HypB/UreG, nucleotide-binding domain AAA_33 PF13671.1 EGC39712.1 - 0.041 13.7 0.1 0.067 13.0 0.0 1.4 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC39712.1 - 0.06 13.6 0.1 0.081 13.2 0.1 1.4 1 1 0 1 1 1 0 AAA domain AAA_29 PF13555.1 EGC39712.1 - 0.069 12.6 0.1 0.12 11.9 0.0 1.4 1 0 0 1 1 1 0 P-loop containing region of AAA domain Dynamin_N PF00350.18 EGC39712.1 - 0.076 12.8 0.4 2.6 7.8 0.3 2.2 1 1 1 2 2 2 0 Dynamin family AAA_17 PF13207.1 EGC39712.1 - 0.12 13.1 0.2 0.28 12.0 0.2 1.8 1 1 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGC39712.1 - 0.17 11.5 0.9 0.29 10.8 0.5 1.6 1 1 0 1 1 1 0 NTPase AAA_16 PF13191.1 EGC39712.1 - 0.19 11.6 0.3 1.6 8.6 0.2 1.9 2 0 0 2 2 2 0 AAA ATPase domain MFS_1 PF07690.11 EGC39714.1 - 1.1e-38 132.8 36.0 7.2e-26 90.7 9.5 2.1 1 1 1 2 2 2 2 Major Facilitator Superfamily DUF1427 PF07235.6 EGC39714.1 - 0.34 11.0 1.7 1.1 9.3 0.2 2.6 3 0 0 3 3 3 0 Protein of unknown function (DUF1427) MFS_2 PF13347.1 EGC39714.1 - 0.96 7.7 32.5 0.2 10.0 5.6 3.1 2 1 1 3 3 3 0 MFS/sugar transport protein DUF485 PF04341.7 EGC39714.1 - 9.3 6.0 15.2 2.6 7.8 0.9 4.1 3 2 2 5 5 5 0 Protein of unknown function, DUF485 UCH PF00443.24 EGC39715.1 - 8.2e-79 264.4 10.0 8.2e-79 264.4 7.0 3.7 2 2 1 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase DUSP PF06337.7 EGC39715.1 - 6.1e-21 74.6 2.1 6.1e-21 74.6 1.5 3.7 4 0 0 4 4 4 1 DUSP domain UCH_1 PF13423.1 EGC39715.1 - 5.5e-15 55.5 16.8 1.3e-06 28.1 5.2 3.1 2 1 1 3 3 3 2 Ubiquitin carboxyl-terminal hydrolase HMA PF00403.21 EGC39716.1 - 3.4e-12 46.3 1.4 4.8e-12 45.8 1.0 1.2 1 1 0 1 1 1 1 Heavy-metal-associated domain Thioredoxin_2 PF13098.1 EGC39716.1 - 0.096 12.8 0.1 0.11 12.7 0.1 1.1 1 0 0 1 1 1 0 Thioredoxin-like domain zf-TRAF PF02176.13 EGC39717.1 - 1.4e-17 63.7 32.3 2.7e-12 46.8 3.3 4.1 2 1 2 4 4 4 3 TRAF-type zinc finger Sina PF03145.11 EGC39717.1 - 3.4e-05 23.5 14.4 0.002 17.8 1.0 3.6 1 1 1 3 3 3 3 Seven in absentia protein family zf-C3HC4_2 PF13923.1 EGC39717.1 - 0.00023 21.1 9.8 0.00023 21.1 6.8 3.7 2 1 1 3 3 3 1 Zinc finger, C3HC4 type (RING finger) DUF325 PF03804.8 EGC39717.1 - 0.075 12.7 0.1 0.19 11.4 0.0 1.7 1 0 0 1 1 1 0 Viral domain of unknown function zf-TRAF PF02176.13 EGC39719.1 - 4.1e-15 55.9 38.8 1.2e-09 38.4 5.6 4.3 2 1 2 4 4 4 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC39719.1 - 1.1e-05 25.3 14.9 1.1e-05 25.3 10.4 3.6 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC39719.1 - 5.9e-05 22.6 10.1 5.9e-05 22.6 7.0 3.6 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) Sina PF03145.11 EGC39719.1 - 0.00029 20.5 22.9 0.0021 17.7 1.0 3.9 2 1 2 4 4 4 3 Seven in absentia protein family zf-RING_2 PF13639.1 EGC39719.1 - 0.02 14.7 11.2 0.02 14.7 7.8 3.9 4 0 0 4 4 4 0 Ring finger domain IncA PF04156.9 EGC39719.1 - 1.1 8.8 5.1 0.18 11.4 0.8 1.7 2 0 0 2 2 2 0 IncA protein MAP65_ASE1 PF03999.7 EGC39720.1 - 5.3e-25 88.0 83.1 2.2e-22 79.4 21.0 3.9 2 2 2 4 4 4 3 Microtubule associated protein (MAP65/ASE1 family) DUF2789 PF10982.3 EGC39720.1 - 0.25 11.3 10.4 5.5 7.0 0.3 4.7 3 1 1 4 4 4 0 Protein of unknown function (DUF2789) CAF1 PF04857.15 EGC39721.1 - 3.2e-68 229.9 0.3 4.9e-68 229.3 0.2 1.3 1 1 0 1 1 1 1 CAF1 family ribonuclease Pkinase PF00069.20 EGC39722.1 - 7.6e-73 244.8 0.0 1e-72 244.4 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39722.1 - 6.1e-53 179.5 0.0 8.3e-53 179.0 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Mst1_SARAH PF11629.3 EGC39722.1 - 0.00032 20.4 1.8 0.00032 20.4 1.2 2.2 2 0 0 2 2 2 1 C terminal SARAH domain of Mst1 Kinase-like PF14531.1 EGC39722.1 - 0.086 11.7 0.0 0.15 10.9 0.0 1.4 1 0 0 1 1 1 0 Kinase-like VPS9 PF02204.13 EGC39723.1 - 1.4e-14 53.9 0.2 6e-14 51.9 0.1 2.1 1 0 0 1 1 1 1 Vacuolar sorting protein 9 (VPS9) domain ubiquitin PF00240.18 EGC39724.1 - 3.8e-10 39.0 0.5 4.4e-10 38.7 0.3 1.0 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC39724.1 - 2.6e-06 27.0 0.6 4e-06 26.4 0.4 1.3 1 1 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC39724.1 - 0.00012 22.2 0.3 0.00044 20.4 0.2 1.8 1 1 0 1 1 1 1 Ubiquitin-like domain YukD PF08817.5 EGC39724.1 - 0.081 13.4 0.1 0.13 12.8 0.1 1.6 1 1 0 1 1 1 0 WXG100 protein secretion system (Wss), protein YukD ThiS PF02597.15 EGC39724.1 - 0.14 12.5 0.1 0.25 11.7 0.1 1.4 1 1 0 1 1 1 0 ThiS family Aminotran_5 PF00266.14 EGC39725.1 - 3.6e-15 55.5 0.0 4.9e-15 55.1 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V SHMT PF00464.14 EGC39725.1 - 0.042 12.2 0.0 0.06 11.7 0.0 1.2 1 0 0 1 1 1 0 Serine hydroxymethyltransferase Cys_Met_Meta_PP PF01053.15 EGC39725.1 - 0.047 11.9 0.0 0.068 11.4 0.0 1.2 1 0 0 1 1 1 0 Cys/Met metabolism PLP-dependent enzyme CUE PF02845.11 EGC39726.1 - 0.072 12.5 0.0 0.15 11.5 0.0 1.6 1 0 0 1 1 1 0 CUE domain Duffy_binding PF05424.6 EGC39726.1 - 0.19 11.5 2.1 0.31 10.8 1.5 1.3 1 0 0 1 1 1 0 Duffy binding domain COBRA1 PF06209.8 EGC39727.1 - 4.4e-70 236.6 6.9 4.4e-70 236.6 4.8 2.0 2 1 1 3 3 3 1 Cofactor of BRCA1 (COBRA1) CK_II_beta PF01214.13 EGC39727.1 - 0.13 11.7 2.6 0.16 11.4 0.6 2.0 2 0 0 2 2 2 0 Casein kinase II regulatory subunit Erf4 PF10256.4 EGC39728.1 - 0.019 14.8 0.4 0.061 13.1 0.3 1.8 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family Erf4 PF10256.4 EGC39729.1 - 6.5e-06 26.0 0.7 0.00011 22.0 0.5 2.0 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family rpo132 PF12415.3 EGC39729.1 - 0.011 14.6 0.2 0.042 12.7 0.1 2.1 1 1 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase Erf4 PF10256.4 EGC39730.1 - 0.016 15.0 2.0 0.11 12.4 1.4 2.0 1 1 0 1 1 1 0 Golgin subfamily A member 7/ERF4 family DUF3487 PF11990.3 EGC39730.1 - 0.022 14.1 0.8 0.03 13.7 0.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3487) CSTF2_hinge PF14327.1 EGC39730.1 - 0.034 14.2 0.0 0.064 13.3 0.0 1.4 1 0 0 1 1 1 0 Hinge domain of cleavage stimulation factor subunit 2 ABC_membrane_3 PF13748.1 EGC39730.1 - 0.038 13.0 1.7 0.056 12.4 1.2 1.3 1 0 0 1 1 1 0 ABC transporter transmembrane region DUF2207 PF09972.4 EGC39730.1 - 0.044 12.3 3.4 0.069 11.7 2.4 1.3 1 0 0 1 1 1 0 Predicted membrane protein (DUF2207) DUF1673 PF07895.6 EGC39730.1 - 0.087 12.3 2.1 0.12 11.9 1.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF1673) Wzy_C PF04932.10 EGC39730.1 - 0.56 9.9 4.8 0.98 9.1 3.4 1.4 1 1 0 1 1 1 0 O-Antigen ligase SdpI PF13630.1 EGC39730.1 - 0.88 9.3 9.6 5.8 6.7 6.2 2.1 2 0 0 2 2 2 0 SdpI/YhfL protein family FNIP PF05725.7 EGC39732.1 - 6.6e-86 282.0 39.3 4.3e-15 55.3 0.1 8.0 3 3 5 9 9 9 9 FNIP Repeat Ras PF00071.17 EGC39733.1 - 6.1e-33 113.4 0.1 7e-33 113.3 0.1 1.0 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39733.1 - 7.8e-16 58.6 0.0 1.2e-15 58.0 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39733.1 - 2.6e-12 46.3 0.2 3.2e-12 46.0 0.1 1.0 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39733.1 - 1.2e-08 34.3 0.0 1.4e-08 34.1 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC39733.1 - 5.9e-06 25.8 0.8 0.063 12.7 0.0 2.2 1 1 0 2 2 2 2 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC39733.1 - 0.0059 16.1 0.0 0.059 12.8 0.0 2.3 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC39733.1 - 0.0059 15.8 0.0 0.0096 15.1 0.0 1.5 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit AAA_24 PF13479.1 EGC39733.1 - 0.016 14.8 0.5 0.019 14.5 0.3 1.7 1 1 0 1 1 1 0 AAA domain MobB PF03205.9 EGC39733.1 - 0.021 14.5 0.7 0.045 13.4 0.1 1.8 2 1 0 2 2 2 0 Molybdopterin guanine dinucleotide synthesis protein B AAA_16 PF13191.1 EGC39733.1 - 0.027 14.4 0.0 0.039 13.9 0.0 1.2 1 0 0 1 1 1 0 AAA ATPase domain ATP_bind_1 PF03029.12 EGC39733.1 - 0.038 13.5 0.1 0.36 10.3 0.0 2.0 1 1 0 2 2 2 0 Conserved hypothetical ATP binding protein AAA_18 PF13238.1 EGC39733.1 - 0.051 13.8 0.2 0.1 12.9 0.0 1.6 2 0 0 2 2 2 0 AAA domain Sex_peptide PF08138.6 EGC39733.1 - 0.061 13.1 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 Sex peptide (SP) family AAA_17 PF13207.1 EGC39733.1 - 0.078 13.8 0.1 0.19 12.5 0.0 1.6 1 1 0 2 2 2 0 AAA domain G-alpha PF00503.15 EGC39733.1 - 0.078 11.6 0.1 2.3 6.8 0.1 2.1 2 0 0 2 2 2 0 G-protein alpha subunit TPR_11 PF13414.1 EGC39734.1 - 2.1e-18 65.6 3.0 2.7e-05 23.7 0.0 3.3 3 0 0 3 3 3 3 TPR repeat TPR_1 PF00515.23 EGC39734.1 - 5e-14 51.2 4.8 1.2e-06 27.8 0.1 3.5 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39734.1 - 9e-13 47.0 1.2 1.5e-05 24.5 0.1 3.6 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC39734.1 - 9.8e-07 28.6 0.6 0.0053 16.6 0.0 2.4 2 0 0 2 2 2 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC39734.1 - 8.6e-05 22.0 9.7 0.0058 16.3 0.1 4.1 4 0 0 4 4 4 2 Tetratricopeptide repeat TPR_16 PF13432.1 EGC39734.1 - 0.00035 21.1 2.5 0.015 15.9 0.6 2.5 3 0 0 3 3 2 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC39734.1 - 0.00058 20.2 0.2 0.068 13.8 0.2 2.4 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC39734.1 - 0.0074 16.0 2.0 1.3 9.0 0.1 2.8 2 0 0 2 2 2 1 Tetratricopeptide repeat TPR_9 PF13371.1 EGC39734.1 - 0.013 15.2 0.0 0.023 14.5 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat MIT PF04212.13 EGC39734.1 - 0.021 14.7 3.9 0.14 12.0 0.4 2.6 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain TPR_15 PF13429.1 EGC39734.1 - 0.045 12.8 0.2 0.27 10.2 0.0 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC39734.1 - 0.14 12.7 0.5 2.7 8.6 0.1 2.6 2 0 0 2 2 2 0 Tetratricopeptide repeat DUF4398 PF14346.1 EGC39734.1 - 4.4 7.3 7.3 1.7 8.7 2.5 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF4398) CtIP_N PF10482.4 EGC39736.1 - 0.0013 18.5 7.7 0.0013 18.5 5.4 2.9 1 1 0 2 2 2 1 Tumour-suppressor protein CtIP N-terminal domain DUF4044 PF13253.1 EGC39736.1 - 0.023 13.8 0.2 0.044 12.9 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) ETRAMP PF09716.5 EGC39736.1 - 0.14 12.1 2.6 0.85 9.6 1.8 2.3 1 1 0 1 1 1 0 Malarial early transcribed membrane protein (ETRAMP) DUF4446 PF14584.1 EGC39736.1 - 1.2 8.9 13.7 6.3 6.6 1.9 2.5 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) Glyco_hydro_47 PF01532.15 EGC39737.1 - 1.5e-39 135.9 0.0 6.5e-39 133.8 0.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolase family 47 DUF2372 PF10178.4 EGC39738.1 - 0.08 13.0 0.0 21 5.3 0.0 3.0 3 0 0 3 3 3 0 Uncharacterised conserved protein (DUF2372) DUF966 PF06136.8 EGC39739.1 - 0.28 10.5 7.9 0.35 10.2 5.5 1.1 1 0 0 1 1 1 0 Domain of unknown function (DUF966) Inhibitor_I53 PF11714.3 EGC39739.1 - 0.42 10.6 7.6 0.95 9.4 5.3 1.6 1 0 0 1 1 1 0 Thrombin inhibitor Madanin Glyco_hydro_47 PF01532.15 EGC39740.1 - 7.2e-47 160.0 0.1 8.9e-47 159.7 0.0 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Glyco_hydro_88 PF07470.8 EGC39740.1 - 0.088 11.8 0.0 0.25 10.3 0.0 1.6 2 0 0 2 2 2 0 Glycosyl Hydrolase Family 88 Nop14 PF04147.7 EGC39742.1 - 0.0018 16.2 9.5 0.0021 16.0 6.6 1.1 1 0 0 1 1 1 1 Nop14-like family DUF4366 PF14283.1 EGC39742.1 - 0.0074 15.7 4.2 0.014 14.8 2.9 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF4366) Daxx PF03344.10 EGC39742.1 - 0.01 14.3 7.5 0.015 13.8 5.2 1.3 1 0 0 1 1 1 0 Daxx Family YL1 PF05764.8 EGC39742.1 - 0.015 14.8 10.1 0.02 14.4 7.0 1.3 1 0 0 1 1 1 0 YL1 nuclear protein PH_4 PF15404.1 EGC39742.1 - 0.018 14.6 0.8 0.018 14.6 0.5 1.5 2 0 0 2 2 2 0 Pleckstrin homology domain FAM176 PF14851.1 EGC39742.1 - 0.019 14.6 3.6 0.046 13.3 2.5 1.7 1 0 0 1 1 1 0 FAM176 family DUF2890 PF11081.3 EGC39742.1 - 0.029 14.4 10.6 0.044 13.8 7.4 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) TRAP_alpha PF03896.11 EGC39742.1 - 0.049 12.6 4.0 0.081 11.9 2.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit DUF3115 PF11312.3 EGC39742.1 - 0.049 12.4 0.0 0.071 11.9 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3115) Spt5_N PF11942.3 EGC39742.1 - 0.19 12.3 18.4 34 5.1 13.6 2.2 2 0 0 2 2 2 0 Spt5 transcription elongation factor, acidic N-terminal CDC45 PF02724.9 EGC39742.1 - 0.47 8.4 9.6 0.72 7.8 6.7 1.2 1 0 0 1 1 1 0 CDC45-like protein Sporozoite_P67 PF05642.6 EGC39742.1 - 6.2 4.5 10.2 8.9 4.0 7.1 1.1 1 0 0 1 1 1 0 Sporozoite P67 surface antigen RXT2_N PF08595.6 EGC39742.1 - 6.4 6.5 12.0 0.77 9.5 5.0 1.8 2 0 0 2 2 2 0 RXT2-like, N-terminal CtIP_N PF10482.4 EGC39743.1 - 0.0014 18.3 8.2 0.0014 18.3 5.7 3.0 1 1 2 3 3 3 1 Tumour-suppressor protein CtIP N-terminal domain Birna_RdRp PF04197.7 EGC39743.1 - 0.2 9.6 14.4 0.22 9.4 10.0 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF4446 PF14584.1 EGC39743.1 - 1 9.2 16.0 4.4 7.1 3.2 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) CtIP_N PF10482.4 EGC39744.1 - 0.0013 18.5 8.4 0.0013 18.5 5.8 3.0 1 1 2 3 3 3 2 Tumour-suppressor protein CtIP N-terminal domain Birna_RdRp PF04197.7 EGC39744.1 - 0.58 8.1 13.5 0.64 7.9 9.4 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) DUF4446 PF14584.1 EGC39744.1 - 0.78 9.5 15.5 8.1 6.2 3.8 2.8 1 1 1 2 2 2 0 Protein of unknown function (DUF4446) PMI_typeI PF01238.16 EGC39745.1 - 1.1e-95 320.7 0.0 1.3e-94 317.3 0.0 2.0 1 1 0 1 1 1 1 Phosphomannose isomerase type I Cupin_2 PF07883.6 EGC39745.1 - 0.00059 19.2 0.0 0.48 9.9 0.0 2.3 2 0 0 2 2 2 2 Cupin domain AraC_binding PF02311.14 EGC39745.1 - 0.014 15.0 0.0 2.9 7.5 0.0 2.5 2 0 0 2 2 2 0 AraC-like ligand binding domain SprB PF13573.1 EGC39746.1 - 0.25 10.9 11.3 1.6 8.3 0.2 4.8 4 0 0 4 4 4 0 SprB repeat LRR_6 PF13516.1 EGC39747.1 - 2.1e-13 48.8 35.9 0.083 13.0 0.0 11.0 11 0 0 11 11 11 7 Leucine Rich repeat LRR_4 PF12799.2 EGC39747.1 - 2.9e-11 42.7 34.6 2.4e-05 23.8 0.8 8.0 4 4 2 7 7 7 6 Leucine Rich repeats (2 copies) LRR_1 PF00560.28 EGC39747.1 - 7.8e-07 28.2 21.7 3.9 7.8 0.0 8.8 6 2 0 6 6 6 4 Leucine Rich Repeat LRR_7 PF13504.1 EGC39747.1 - 6.1e-06 25.6 15.7 4.1 8.0 0.0 8.7 9 1 0 9 9 9 2 Leucine rich repeat LRR_8 PF13855.1 EGC39747.1 - 0.0028 17.3 31.9 0.13 12.0 0.2 8.8 2 2 7 9 9 9 2 Leucine rich repeat COX6B PF02297.12 EGC39748.1 - 4.1e-19 68.3 4.5 4.8e-19 68.1 3.1 1.1 1 0 0 1 1 1 1 Cytochrome oxidase c subunit VIb CHCH PF06747.8 EGC39748.1 - 0.016 15.0 1.0 0.016 15.0 0.7 1.6 1 1 0 1 1 1 0 CHCH domain zf-P11 PF03854.9 EGC39748.1 - 0.35 10.3 2.0 0.48 9.9 1.4 1.2 1 0 0 1 1 1 0 P-11 zinc finger SpoIIID PF12116.3 EGC39749.1 - 0.81 9.6 5.1 3.8 7.4 0.2 2.9 3 0 0 3 3 3 0 Stage III sporulation protein D Esterase_phd PF10503.4 EGC39750.1 - 3e-06 26.6 0.1 0.00028 20.1 0.0 2.2 2 0 0 2 2 2 2 Esterase PHB depolymerase FNIP PF05725.7 EGC39751.1 - 3.5e-89 292.5 115.1 1.4e-10 40.9 1.2 12.3 6 2 10 16 16 16 16 FNIP Repeat DUF1769 PF08588.5 EGC39751.1 - 0.0032 17.3 3.7 2.6 8.0 0.0 5.8 5 2 2 7 7 7 1 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC39751.1 - 0.41 10.3 8.8 2.7 7.7 0.5 4.0 2 1 2 4 4 4 0 Leucine rich repeats (6 copies) LRR_7 PF13504.1 EGC39751.1 - 1.7 9.1 4.7 1e+02 3.8 0.0 5.5 6 0 0 6 6 6 0 Leucine rich repeat DNMT1-RFD PF12047.3 EGC39752.1 - 0.0016 18.1 3.7 0.0016 18.1 2.6 2.5 2 1 0 2 2 2 1 Cytosine specific DNA methyltransferase replication foci domain Xpo1 PF08389.7 EGC39753.1 - 6e-21 74.9 2.5 6e-21 74.9 1.7 5.0 4 2 3 7 7 7 1 Exportin 1-like protein IBN_N PF03810.14 EGC39753.1 - 4.2e-05 23.3 2.4 4.2e-05 23.3 1.7 4.1 3 1 0 3 3 3 1 Importin-beta N-terminal domain XPG_I_2 PF12813.2 EGC39753.1 - 0.36 10.2 2.6 4.8 6.5 0.8 2.9 3 0 0 3 3 3 0 XPG domain containing Mo25 PF08569.6 EGC39754.1 - 5.5e-130 433.2 16.6 6.1e-130 433.1 11.5 1.0 1 0 0 1 1 1 1 Mo25-like HEAT_2 PF13646.1 EGC39754.1 - 0.01 16.1 0.0 0.029 14.6 0.0 1.7 1 0 0 1 1 1 0 HEAT repeats HEAT PF02985.17 EGC39754.1 - 0.047 13.7 0.0 6.7 7.0 0.0 2.9 2 0 0 2 2 2 0 HEAT repeat DNA_repr_REX1B PF14966.1 EGC39755.1 - 5.7e-27 93.9 0.8 5.7e-27 93.9 0.6 1.9 2 0 0 2 2 2 1 DNA repair REX1-B UBN2 PF14223.1 EGC39755.1 - 0.0049 16.6 7.6 0.017 14.9 1.0 2.3 1 1 1 2 2 2 1 gag-polypeptide of LTR copia-type SMC_Nse1 PF07574.8 EGC39755.1 - 0.0094 15.5 0.5 0.0094 15.5 0.3 2.3 2 1 1 3 3 3 1 Nse1 non-SMC component of SMC5-6 complex RTBV_P12 PF06361.6 EGC39755.1 - 0.017 15.3 2.1 0.36 11.0 0.3 2.4 1 1 1 2 2 2 0 Rice tungro bacilliform virus P12 protein KMP11 PF03037.11 EGC39755.1 - 0.024 15.1 5.5 0.14 12.8 0.7 2.6 2 1 0 2 2 2 0 Kinetoplastid membrane protein 11 Lectin_N PF03954.9 EGC39755.1 - 0.029 13.7 3.2 0.035 13.4 0.1 2.0 1 1 1 2 2 2 0 Hepatic lectin, N-terminal domain KapB PF08810.5 EGC39755.1 - 0.066 13.2 2.0 6.1 6.9 0.2 2.3 2 0 0 2 2 2 0 Kinase associated protein B DUF148 PF02520.12 EGC39755.1 - 0.081 12.7 5.2 0.039 13.7 1.2 2.2 2 1 0 2 2 2 0 Domain of unknown function DUF148 BRE1 PF08647.6 EGC39755.1 - 0.29 11.1 4.5 0.13 12.2 0.9 2.0 1 1 1 2 2 2 0 BRE1 E3 ubiquitin ligase Kinetocho_Slk19 PF12709.2 EGC39755.1 - 0.34 11.0 4.1 1.1 9.4 0.0 3.0 2 1 1 3 3 3 0 Central kinetochore-associated Laminin_II PF06009.7 EGC39755.1 - 1.8 8.3 7.8 1.2 8.8 1.9 2.2 2 0 0 2 2 2 0 Laminin Domain II Tropomyosin_1 PF12718.2 EGC39755.1 - 5.2 6.9 11.1 6.3 6.6 1.6 2.2 1 1 1 2 2 2 0 Tropomyosin like Skp1_POZ PF03931.10 EGC39756.1 - 9.9e-10 38.3 0.0 1.9e-09 37.4 0.0 1.4 1 0 0 1 1 1 1 Skp1 family, tetramerisation domain BTB PF00651.26 EGC39756.1 - 0.00014 21.8 0.2 0.00019 21.4 0.1 1.3 1 0 0 1 1 1 1 BTB/POZ domain ProRS-C_1 PF09180.6 EGC39757.1 - 8.4e-26 89.6 4.6 2.5e-25 88.1 3.2 1.9 1 0 0 1 1 1 1 Prolyl-tRNA synthetase, C-terminal HGTP_anticodon PF03129.15 EGC39757.1 - 5.6e-21 74.2 0.0 1.1e-20 73.3 0.0 1.6 1 0 0 1 1 1 1 Anticodon binding domain tRNA-synt_2b PF00587.20 EGC39757.1 - 7.5e-19 67.9 0.0 2.8e-18 66.1 0.0 1.9 2 0 0 2 2 2 1 tRNA synthetase class II core domain (G, H, P, S and T) SYF2 PF08231.7 EGC39758.1 - 7.4e-28 97.6 17.6 7.4e-28 97.6 12.2 3.0 1 1 2 3 3 3 1 SYF2 splicing factor DUF1178 PF06676.6 EGC39758.1 - 1.4 9.1 10.0 0.2 11.8 3.4 2.1 1 1 1 2 2 2 0 Protein of unknown function (DUF1178) NAM PF02365.10 EGC39760.1 - 0.0007 19.7 0.2 0.0017 18.5 0.1 1.7 2 0 0 2 2 2 1 No apical meristem (NAM) protein TPR_11 PF13414.1 EGC39762.1 - 3.4e-14 52.2 9.7 1.1e-09 37.7 0.4 4.4 3 1 1 4 4 4 2 TPR repeat SET PF00856.23 EGC39762.1 - 5.8e-10 39.6 0.4 2.8e-09 37.4 0.1 2.4 2 0 0 2 2 2 1 SET domain TPR_1 PF00515.23 EGC39762.1 - 3.6e-09 35.8 8.3 1e-05 24.8 0.3 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39762.1 - 3.9e-09 35.7 11.4 6e-05 22.6 0.4 5.0 5 0 0 5 5 5 3 Tetratricopeptide repeat zf-MYND PF01753.13 EGC39762.1 - 1.3e-05 24.9 10.0 1.3e-05 24.9 7.0 2.1 2 0 0 2 2 2 1 MYND finger TPR_12 PF13424.1 EGC39762.1 - 1.4e-05 24.9 6.7 0.21 11.5 0.1 4.1 2 2 3 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC39762.1 - 0.0018 17.9 6.6 0.45 10.3 0.1 4.3 3 0 0 3 3 3 2 Tetratricopeptide repeat RNase_PH PF01138.16 EGC39763.1 - 1.1e-23 83.9 0.4 1.8e-23 83.3 0.3 1.3 1 0 0 1 1 1 1 3' exoribonuclease family, domain 1 RNase_PH_C PF03725.10 EGC39763.1 - 4.7e-06 26.4 0.4 1.2e-05 25.1 0.3 1.7 1 0 0 1 1 1 1 3' exoribonuclease family, domain 2 Met_10 PF02475.11 EGC39763.1 - 0.016 14.7 0.1 0.019 14.5 0.0 1.3 1 0 0 1 1 1 0 Met-10+ like-protein GRP PF07172.6 EGC39764.1 - 3.1 8.3 0.0 3.1 8.3 0.0 2.7 3 1 0 3 3 3 0 Glycine rich protein family Nop14 PF04147.7 EGC39764.1 - 4.3 5.1 36.7 7.6 4.3 25.4 1.3 1 0 0 1 1 1 0 Nop14-like family Hid1 PF12722.2 EGC39764.1 - 5.3 4.6 14.4 7.9 4.0 10.0 1.3 1 0 0 1 1 1 0 High-temperature-induced dauer-formation protein FNIP PF05725.7 EGC39765.1 - 1.7e-21 75.8 63.9 2.1e-06 27.5 0.1 12.0 7 3 5 12 12 12 8 FNIP Repeat LRR_8 PF13855.1 EGC39765.1 - 0.0089 15.7 1.4 0.0089 15.7 1.0 4.7 4 1 0 4 4 4 1 Leucine rich repeat Ras PF00071.17 EGC39766.1 - 8.9e-45 151.9 0.1 1.1e-44 151.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39766.1 - 1.8e-19 70.3 0.0 2.9e-19 69.6 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39766.1 - 4.5e-10 39.0 0.1 5.8e-10 38.6 0.1 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39766.1 - 2.4e-07 30.1 0.0 2.7e-07 29.9 0.0 1.1 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC39766.1 - 0.00026 20.4 0.7 0.02 14.3 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain PduV-EutP PF10662.4 EGC39766.1 - 0.00064 19.2 0.0 0.0069 15.8 0.0 2.2 2 1 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation MobB PF03205.9 EGC39766.1 - 0.0011 18.6 0.4 0.013 15.2 0.1 2.1 2 0 0 2 2 2 1 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EGC39766.1 - 0.0044 16.2 0.0 0.013 14.7 0.0 1.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit ATP_bind_1 PF03029.12 EGC39766.1 - 0.0046 16.5 0.0 0.24 10.9 0.0 2.1 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein AAA_16 PF13191.1 EGC39766.1 - 0.022 14.7 0.0 0.035 14.0 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain MMR_HSR1 PF01926.18 EGC39766.1 - 0.029 14.3 0.0 0.045 13.6 0.0 1.3 1 0 0 1 1 1 0 50S ribosome-binding GTPase UPF0079 PF02367.12 EGC39766.1 - 0.037 13.6 0.0 0.69 9.5 0.0 2.3 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_24 PF13479.1 EGC39766.1 - 0.042 13.4 0.2 0.083 12.4 0.1 1.6 1 1 0 1 1 1 0 AAA domain AAA PF00004.24 EGC39766.1 - 0.081 13.1 0.0 0.18 11.9 0.0 1.6 2 0 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) Arch_ATPase PF01637.13 EGC39766.1 - 0.099 12.3 0.0 0.16 11.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase DUF815 PF05673.8 EGC39766.1 - 0.11 11.3 0.0 0.34 9.7 0.0 1.7 2 0 0 2 2 2 0 Protein of unknown function (DUF815) AAA_32 PF13654.1 EGC39766.1 - 0.13 10.9 0.1 0.22 10.1 0.1 1.3 1 0 0 1 1 1 0 AAA domain AAA_22 PF13401.1 EGC39766.1 - 0.13 12.4 0.0 0.2 11.7 0.0 1.3 1 0 0 1 1 1 0 AAA domain AAA_18 PF13238.1 EGC39766.1 - 0.14 12.4 0.1 0.39 11.0 0.0 1.8 2 0 0 2 2 2 0 AAA domain Proteasome PF00227.21 EGC39767.1 - 3.7e-48 163.3 0.9 4.5e-48 163.0 0.6 1.1 1 0 0 1 1 1 1 Proteasome subunit Pr_beta_C PF12465.3 EGC39767.1 - 0.27 10.5 0.0 0.27 10.5 0.0 2.2 2 0 0 2 2 2 0 Proteasome beta subunits C terminal LIM PF00412.17 EGC39768.1 - 2.7e-20 72.1 35.4 3.5e-08 33.3 4.4 3.4 3 0 0 3 3 3 3 LIM domain STAG PF08514.6 EGC39769.1 - 1.5e-18 66.6 0.5 1.5e-18 66.6 0.3 3.4 3 1 0 3 3 3 1 STAG domain DUF3429 PF11911.3 EGC39769.1 - 0.29 11.1 0.0 0.59 10.1 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF3429) BSP_II PF05432.6 EGC39769.1 - 0.54 9.4 26.8 0.47 9.6 1.3 2.7 2 0 0 2 2 2 0 Bone sialoprotein II (BSP-II) AAA_11 PF13086.1 EGC39771.1 - 3.8e-20 72.4 0.0 1.1e-08 35.0 0.0 3.2 2 1 1 3 3 3 2 AAA domain AAA_12 PF13087.1 EGC39771.1 - 9.7e-14 51.2 2.5 1.2e-13 50.9 0.6 2.1 2 0 0 2 2 2 1 AAA domain AAA_30 PF13604.1 EGC39771.1 - 7.9e-10 38.6 0.0 4.6e-09 36.1 0.0 2.0 1 1 0 1 1 1 1 AAA domain Viral_helicase1 PF01443.13 EGC39771.1 - 2.5e-07 30.4 0.1 0.0066 15.9 0.0 3.5 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase AAA_19 PF13245.1 EGC39771.1 - 2.4e-06 27.2 0.0 7.4e-06 25.6 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain PhoH PF02562.11 EGC39771.1 - 0.00015 21.1 0.0 0.051 12.8 0.0 2.4 2 0 0 2 2 2 2 PhoH-like protein Helicase_RecD PF05127.9 EGC39771.1 - 0.0052 16.4 0.0 0.015 14.8 0.0 1.8 1 0 0 1 1 1 1 Helicase AAA_22 PF13401.1 EGC39771.1 - 0.067 13.3 0.0 0.45 10.6 0.0 2.4 1 1 0 1 1 1 0 AAA domain SIN1 PF05422.7 EGC39772.1 - 1.1e-08 34.0 0.0 1.1e-08 34.0 0.0 3.5 2 1 0 2 2 2 1 Stress-activated map kinase interacting protein 1 (SIN1) RBD PF02196.10 EGC39772.1 - 0.0025 17.5 0.0 0.0052 16.5 0.0 1.5 1 0 0 1 1 1 1 Raf-like Ras-binding domain PLDc_2 PF13091.1 EGC39773.1 - 5.1e-30 103.8 0.5 2.8e-19 69.0 0.0 2.8 3 0 0 3 3 3 2 PLD-like domain PLDc PF00614.17 EGC39773.1 - 4.8e-09 35.7 1.6 2.7e-05 23.7 0.1 3.0 2 0 0 2 2 2 2 Phospholipase D Active site motif RRM_1 PF00076.17 EGC39775.1 - 5.7e-41 138.0 0.8 8.6e-16 57.3 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC39775.1 - 7.3e-28 96.1 0.8 3.8e-10 39.4 0.0 3.4 3 0 0 3 3 3 3 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC39775.1 - 6.4e-26 90.1 0.5 1.5e-11 44.0 0.0 3.6 4 0 0 4 4 4 3 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RBM39linker PF15519.1 EGC39775.1 - 1.4e-11 44.5 1.7 6.1e-11 42.4 1.2 2.2 1 1 0 1 1 1 1 linker between RRM2 and RRM3 domains in RBM39 protein RRM_3 PF08777.6 EGC39775.1 - 0.00015 21.5 7.3 0.0026 17.5 0.0 3.6 4 0 0 4 4 4 2 RNA binding motif Nup35_RRM_2 PF14605.1 EGC39775.1 - 0.00016 21.3 1.1 0.22 11.3 0.0 3.5 4 0 0 4 4 4 2 Nup53/35/40-type RNA recognition motif Limkain-b1 PF11608.3 EGC39775.1 - 0.0042 16.8 0.0 0.12 12.1 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 Fcf1 PF04900.7 EGC39776.1 - 7.4e-18 64.5 0.0 7.4e-18 64.5 0.0 2.6 2 1 0 2 2 2 1 Fcf1 NAD_binding_10 PF13460.1 EGC39777.1 - 5.2e-12 46.1 0.0 6.5e-12 45.8 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC39777.1 - 1.9e-09 37.3 0.2 3.1e-08 33.3 0.2 2.5 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family NmrA PF05368.8 EGC39777.1 - 5.8e-05 22.4 0.3 0.00031 20.0 0.0 2.0 2 0 0 2 2 2 1 NmrA-like family 3Beta_HSD PF01073.14 EGC39777.1 - 0.0094 14.6 1.4 0.39 9.3 0.1 2.5 2 1 0 2 2 2 1 3-beta hydroxysteroid dehydrogenase/isomerase family NAD_binding_2 PF03446.10 EGC39777.1 - 0.01 15.6 0.0 0.019 14.7 0.0 1.5 1 0 0 1 1 1 0 NAD binding domain of 6-phosphogluconate dehydrogenase DapB_N PF01113.15 EGC39777.1 - 0.015 15.2 0.0 0.038 13.8 0.0 1.7 1 0 0 1 1 1 0 Dihydrodipicolinate reductase, N-terminus adh_short PF00106.20 EGC39777.1 - 0.018 14.9 0.1 0.03 14.2 0.1 1.5 1 1 0 1 1 1 0 short chain dehydrogenase Pyr_redox PF00070.22 EGC39777.1 - 0.02 15.3 0.1 0.047 14.1 0.0 1.7 1 0 0 1 1 1 0 Pyridine nucleotide-disulphide oxidoreductase ApbA PF02558.11 EGC39777.1 - 0.041 13.3 0.0 0.082 12.3 0.0 1.5 1 0 0 1 1 1 0 Ketopantoate reductase PanE/ApbA Shikimate_DH PF01488.15 EGC39777.1 - 0.05 13.7 0.1 0.19 11.8 0.0 1.9 2 0 0 2 2 2 0 Shikimate / quinate 5-dehydrogenase 3HCDH_N PF02737.13 EGC39777.1 - 0.075 12.6 0.1 0.21 11.2 0.1 1.7 1 0 0 1 1 1 0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain TrkA_N PF02254.13 EGC39777.1 - 0.081 12.9 0.2 0.28 11.2 0.0 1.9 2 0 0 2 2 2 0 TrkA-N domain DUF4225 PF13988.1 EGC39777.1 - 0.098 12.1 0.5 0.26 10.7 0.4 1.8 1 1 0 1 1 1 0 Protein of unknown function (DUF4225) ThiF PF00899.16 EGC39777.1 - 0.79 9.5 4.0 0.72 9.6 0.8 2.1 1 1 1 2 2 2 0 ThiF family Vfa1 PF08432.5 EGC39778.1 - 0.09 12.7 7.5 0.26 11.2 5.2 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 Phi-29_GP4 PF05464.6 EGC39779.1 - 0.093 12.6 0.8 0.11 12.3 0.6 1.1 1 0 0 1 1 1 0 Phi-29-like late genes activator (early protein GP4) AIG1 PF04548.11 EGC39781.1 - 5.1e-22 78.0 0.0 8.8e-22 77.2 0.0 1.4 1 0 0 1 1 1 1 AIG1 family MMR_HSR1 PF01926.18 EGC39781.1 - 1.6e-09 37.7 0.0 3.6e-09 36.5 0.0 1.6 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC39781.1 - 6.3e-05 22.2 0.2 0.00016 20.9 0.2 1.6 1 1 0 1 1 1 1 Protein of unknown function, DUF258 Gtr1_RagA PF04670.7 EGC39781.1 - 0.0019 17.3 0.1 0.0033 16.5 0.0 1.4 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region G-alpha PF00503.15 EGC39781.1 - 0.0022 16.7 0.1 0.0038 15.9 0.1 1.4 1 1 0 1 1 1 1 G-protein alpha subunit Dynamin_N PF00350.18 EGC39781.1 - 0.0026 17.5 4.3 0.037 13.8 0.1 3.1 2 1 1 3 3 3 1 Dynamin family Septin PF00735.13 EGC39781.1 - 0.0031 16.5 0.2 0.012 14.6 0.1 1.9 1 1 0 1 1 1 1 Septin AAA_16 PF13191.1 EGC39781.1 - 0.0051 16.8 0.0 0.012 15.6 0.0 1.6 1 0 0 1 1 1 1 AAA ATPase domain T2SE PF00437.15 EGC39781.1 - 0.011 14.6 0.0 0.019 13.8 0.0 1.4 1 0 0 1 1 1 0 Type II/IV secretion system protein SR-25 PF10500.4 EGC39781.1 - 0.025 14.0 7.5 0.037 13.4 5.2 1.3 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein DUF815 PF05673.8 EGC39781.1 - 0.025 13.4 0.0 0.047 12.6 0.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF815) ABC_tran PF00005.22 EGC39781.1 - 0.033 14.4 0.0 0.064 13.5 0.0 1.6 1 0 0 1 1 1 0 ABC transporter FtsK_SpoIIIE PF01580.13 EGC39781.1 - 0.04 13.3 0.1 0.12 11.8 0.0 1.8 2 0 0 2 2 2 0 FtsK/SpoIIIE family FeoB_N PF02421.13 EGC39781.1 - 0.061 12.6 0.0 0.096 11.9 0.0 1.3 1 0 0 1 1 1 0 Ferrous iron transport protein B AAA_29 PF13555.1 EGC39781.1 - 0.065 12.7 0.0 0.16 11.4 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain IstB_IS21 PF01695.12 EGC39781.1 - 0.066 12.6 0.0 0.13 11.6 0.0 1.4 1 0 0 1 1 1 0 IstB-like ATP binding protein Sigma54_activat PF00158.21 EGC39781.1 - 0.16 11.4 0.0 0.27 10.7 0.0 1.3 1 0 0 1 1 1 0 Sigma-54 interaction domain RAP1 PF07218.6 EGC39781.1 - 1.6 6.7 7.9 1.9 6.4 5.4 1.1 1 0 0 1 1 1 0 Rhoptry-associated protein 1 (RAP-1) ORC6 PF05460.8 EGC39781.1 - 2.1 7.3 8.6 3.1 6.8 6.0 1.1 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) SPC25 PF06703.6 EGC39782.1 - 0.0018 17.8 0.3 0.0026 17.3 0.2 1.3 1 0 0 1 1 1 1 Microsomal signal peptidase 25 kDa subunit (SPC25) Prp19 PF08606.6 EGC39783.1 - 2.4e-32 110.4 1.7 5.7e-32 109.2 1.2 1.7 1 0 0 1 1 1 1 Prp19/Pso4-like WD40 PF00400.27 EGC39783.1 - 1.2e-23 82.0 8.0 1.8e-07 30.7 0.0 7.0 7 0 0 7 7 7 5 WD domain, G-beta repeat zf-Nse PF11789.3 EGC39783.1 - 0.015 14.7 0.0 0.031 13.7 0.0 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit BofC_C PF08955.5 EGC39783.1 - 0.066 13.2 0.0 7 6.7 0.0 3.1 3 0 0 3 3 3 0 BofC C-terminal domain 2-Hacid_dh_C PF02826.14 EGC39784.1 - 2.7e-62 209.0 0.0 7.1e-62 207.7 0.0 1.6 2 0 0 2 2 2 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC39784.1 - 5.8e-30 103.4 0.1 6.6e-30 103.3 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC39784.1 - 3.4e-08 33.5 0.4 1.8e-07 31.1 0.0 2.2 2 1 0 2 2 2 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGC39784.1 - 0.00014 21.2 0.2 0.0011 18.4 0.0 2.1 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EGC39784.1 - 0.00028 21.2 0.0 0.017 15.5 0.0 2.4 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent CPSF73-100_C PF11718.3 EGC39784.1 - 0.014 14.7 0.1 0.023 14.0 0.1 1.4 1 0 0 1 1 1 0 Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term Gp_dh_N PF00044.19 EGC39784.1 - 0.075 12.9 1.2 0.2 11.6 0.1 2.2 2 1 0 2 2 2 0 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain GFO_IDH_MocA PF01408.17 EGC39784.1 - 0.1 13.0 0.0 0.3 11.6 0.0 1.8 1 1 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold 2-Hacid_dh_C PF02826.14 EGC39785.1 - 4.5e-62 208.3 0.0 7.5e-62 207.6 0.0 1.3 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC39785.1 - 1.1e-28 99.2 0.1 1.3e-28 99.0 0.1 1.0 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC39785.1 - 4e-07 30.0 0.0 9.7e-07 28.7 0.0 1.7 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGC39785.1 - 0.00072 18.9 0.1 0.0021 17.4 0.0 1.8 2 0 0 2 2 2 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EGC39785.1 - 0.0077 16.6 0.0 0.057 13.8 0.0 2.2 2 0 0 2 2 2 1 NADP oxidoreductase coenzyme F420-dependent GFO_IDH_MocA PF01408.17 EGC39785.1 - 0.066 13.7 0.0 0.22 12.0 0.0 1.9 1 0 0 1 1 1 0 Oxidoreductase family, NAD-binding Rossmann fold F5_F8_type_C PF00754.20 EGC39787.1 - 3.4e-26 91.5 1.1 3.4e-26 91.5 0.8 2.0 2 0 0 2 2 2 1 F5/8 type C domain H_lectin PF09458.5 EGC39787.1 - 1.9e-19 69.0 0.3 4.9e-19 67.7 0.2 1.7 1 0 0 1 1 1 1 H-type lectin domain Mu-like_Pro PF10123.4 EGC39788.1 - 0.12 11.8 3.1 0.15 11.4 2.2 1.1 1 0 0 1 1 1 0 Mu-like prophage I protein Mucin PF01456.12 EGC39788.1 - 0.37 10.5 12.2 0.54 10.0 8.5 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein ABC2_membrane_3 PF12698.2 EGC39788.1 - 1.4 7.8 6.1 1.6 7.6 4.2 1.2 1 0 0 1 1 1 0 ABC-2 family transporter protein FNIP PF05725.7 EGC39789.1 - 0 1130.6 174.9 8e-16 57.7 0.1 26.2 11 4 20 33 33 33 33 FNIP Repeat Phage_min_tail PF05939.8 EGC39789.1 - 7e-16 58.1 0.6 0.81 9.6 0.0 16.0 8 5 9 20 20 20 2 Phage minor tail protein DUF1769 PF08588.5 EGC39789.1 - 5.2e-07 29.5 91.7 2.7 7.9 0.1 25.6 12 8 17 30 30 30 8 Protein of unknown function (DUF1769) HCaRG PF07258.9 EGC39791.1 - 6.4e-35 120.2 9.5 7.7e-35 120.0 6.6 1.0 1 0 0 1 1 1 1 HCaRG protein DUF3510 PF12022.3 EGC39791.1 - 0.38 10.8 7.4 0.27 11.3 3.1 2.3 1 1 2 3 3 3 0 Domain of unknown function (DUF3510) CRISPR_Cas2 PF09827.4 EGC39791.1 - 0.66 10.1 3.2 0.69 10.0 0.3 2.4 1 1 2 3 3 3 0 CRISPR associated protein Cas2 MARVEL PF01284.18 EGC39792.1 - 0.0044 16.8 0.8 0.0044 16.8 0.6 2.7 1 1 1 2 2 2 1 Membrane-associating domain 2-Hacid_dh_C PF02826.14 EGC39793.1 - 8.7e-57 191.1 0.0 1.5e-56 190.3 0.0 1.4 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 2-Hacid_dh PF00389.25 EGC39793.1 - 2.1e-21 75.7 0.0 2.5e-21 75.5 0.0 1.1 1 0 0 1 1 1 1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain NAD_binding_2 PF03446.10 EGC39793.1 - 8.2e-05 22.4 0.0 0.00013 21.8 0.0 1.3 1 0 0 1 1 1 1 NAD binding domain of 6-phosphogluconate dehydrogenase IlvN PF07991.7 EGC39793.1 - 0.00023 20.5 0.0 0.0004 19.7 0.0 1.4 1 0 0 1 1 1 1 Acetohydroxy acid isomeroreductase, catalytic domain F420_oxidored PF03807.12 EGC39793.1 - 0.0084 16.5 0.0 0.019 15.4 0.0 1.6 1 0 0 1 1 1 1 NADP oxidoreductase coenzyme F420-dependent Calici_MSP PF05752.6 EGC39793.1 - 0.016 14.8 0.0 6.9 6.2 0.0 2.3 2 0 0 2 2 2 0 Calicivirus minor structural protein ThiF PF00899.16 EGC39793.1 - 0.053 13.3 0.5 2.2 8.0 0.0 3.1 3 0 0 3 3 3 0 ThiF family RhoGEF PF00621.15 EGC39794.1 - 2.2e-78 262.2 29.0 1.5e-46 158.5 4.7 3.5 3 0 0 3 3 3 3 RhoGEF domain RhoGAP PF00620.22 EGC39794.1 - 1.9e-44 150.9 5.4 3.2e-44 150.2 0.0 3.1 3 0 0 3 3 3 1 RhoGAP domain SH3_9 PF14604.1 EGC39794.1 - 2.4e-13 49.4 0.1 4.5e-13 48.5 0.1 1.5 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC39794.1 - 2.7e-12 45.8 0.1 5.8e-12 44.7 0.1 1.6 1 0 0 1 1 1 1 SH3 domain PH PF00169.24 EGC39794.1 - 6.3e-09 35.9 2.1 1.3e-08 34.9 0.1 2.7 2 0 0 2 2 2 1 PH domain SH3_2 PF07653.12 EGC39794.1 - 7.9e-08 31.6 0.0 2e-07 30.3 0.0 1.7 1 0 0 1 1 1 1 Variant SH3 domain PH_6 PF15406.1 EGC39794.1 - 0.023 14.7 0.1 0.063 13.3 0.1 1.8 1 0 0 1 1 1 0 Pleckstrin homology domain DMPK_coil PF08826.5 EGC39795.1 - 0.023 14.5 2.9 0.023 14.5 2.0 3.6 3 0 0 3 3 3 0 DMPK coiled coil domain like LST1 PF05083.8 EGC39795.1 - 0.14 12.1 0.7 1.9 8.5 0.2 2.5 2 0 0 2 2 2 0 LST-1 protein Toxin_7 PF05980.7 EGC39797.1 - 0.65 10.0 6.1 1.6 8.8 2.8 2.6 2 0 0 2 2 2 0 Toxin 7 Ank_2 PF12796.2 EGC39798.1 - 4.2e-20 71.8 0.0 1e-19 70.6 0.0 1.7 1 0 0 1 1 1 1 Ankyrin repeats (3 copies) Ank PF00023.25 EGC39798.1 - 3.8e-17 61.1 0.0 2.2e-10 39.8 0.0 3.8 3 0 0 3 3 3 3 Ankyrin repeat Ank_5 PF13857.1 EGC39798.1 - 8.8e-17 60.7 0.1 3e-12 46.3 0.0 3.3 1 1 2 3 3 3 2 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC39798.1 - 1.6e-16 60.3 0.1 1.1e-08 35.2 0.0 3.7 1 1 2 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC39798.1 - 8.1e-12 44.1 0.0 2.6e-06 27.1 0.0 4.1 3 0 0 3 3 3 2 Ankyrin repeat RA PF00788.18 EGC39798.1 - 3.7e-07 30.5 0.4 9e-07 29.2 0.3 1.7 1 0 0 1 1 1 1 Ras association (RalGDS/AF-6) domain Pyridoxal_deC PF00282.14 EGC39799.1 - 2.3e-20 72.4 0.0 6e-20 71.0 0.0 1.6 1 1 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Aminotran_5 PF00266.14 EGC39799.1 - 1.1e-08 34.2 0.0 3.5e-08 32.5 0.0 1.7 2 0 0 2 2 2 1 Aminotransferase class-V Aminotran_1_2 PF00155.16 EGC39799.1 - 2.3e-06 26.8 0.0 3.9e-06 26.0 0.0 1.4 1 0 0 1 1 1 1 Aminotransferase class I and II DegT_DnrJ_EryC1 PF01041.12 EGC39799.1 - 0.0002 20.5 0.0 0.00033 19.8 0.0 1.2 1 0 0 1 1 1 1 DegT/DnrJ/EryC1/StrS aminotransferase family SLA_LP_auto_ag PF05889.8 EGC39799.1 - 0.0021 16.6 0.0 0.0053 15.2 0.0 1.6 2 0 0 2 2 2 1 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) HTH_16 PF12645.2 EGC39799.1 - 0.046 13.6 0.1 0.18 11.7 0.0 2.1 2 0 0 2 2 2 0 Helix-turn-helix domain PIP5K PF01504.13 EGC39800.1 - 7.4e-73 244.7 11.2 1.6e-72 243.6 7.8 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-4-phosphate 5-Kinase PH PF00169.24 EGC39800.1 - 3.7e-11 43.1 0.5 3.7e-11 43.1 0.4 3.1 3 1 0 3 3 3 1 PH domain Abhydrolase_3 PF07859.8 EGC39801.1 - 8.4e-49 165.9 0.0 1e-48 165.7 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold DUF2424 PF10340.4 EGC39801.1 - 0.00062 18.5 0.0 0.0012 17.5 0.0 1.4 1 1 0 1 1 1 1 Protein of unknown function (DUF2424) Peptidase_S9 PF00326.16 EGC39801.1 - 0.011 15.0 0.0 0.055 12.6 0.0 1.9 1 1 0 1 1 1 0 Prolyl oligopeptidase family DLH PF01738.13 EGC39801.1 - 0.013 14.7 0.0 0.023 13.9 0.0 1.4 1 0 0 1 1 1 0 Dienelactone hydrolase family Abhydrolase_5 PF12695.2 EGC39801.1 - 0.018 14.7 0.0 0.027 14.2 0.0 1.3 1 0 0 1 1 1 0 Alpha/beta hydrolase family COesterase PF00135.23 EGC39801.1 - 0.028 13.1 0.0 0.21 10.2 0.0 1.9 2 0 0 2 2 2 0 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC39802.1 - 1.7e-23 83.3 0.0 2.2e-23 82.9 0.0 1.1 1 0 0 1 1 1 1 alpha/beta hydrolase fold GST_C PF00043.20 EGC39802.1 - 0.041 13.8 0.0 0.072 13.0 0.0 1.4 1 0 0 1 1 1 0 Glutathione S-transferase, C-terminal domain COesterase PF00135.23 EGC39802.1 - 0.1 11.3 0.0 0.15 10.7 0.0 1.2 1 0 0 1 1 1 0 Carboxylesterase family LIM_bind PF01803.11 EGC39803.1 - 2.1e-29 102.3 12.1 1.3e-26 93.1 4.5 5.4 3 2 2 5 5 5 2 LIM-domain binding protein Pkinase PF00069.20 EGC39804.1 - 1.5e-61 207.8 0.0 1.8e-61 207.5 0.0 1.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39804.1 - 1.9e-18 66.4 0.0 2.8e-18 65.9 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC39804.1 - 8.2e-08 32.2 0.0 4.3e-07 29.9 0.0 2.0 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC39804.1 - 0.011 15.3 0.3 0.023 14.2 0.2 1.6 1 0 0 1 1 1 0 Choline/ethanolamine kinase YrbL-PhoP_reg PF10707.4 EGC39804.1 - 0.011 15.0 0.4 2.1 7.6 0.0 2.5 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGC39804.1 - 0.14 11.1 0.1 0.28 10.2 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family OmpH PF03938.9 EGC39805.1 - 0.00063 19.7 4.2 0.00063 19.7 2.9 4.3 2 1 0 2 2 2 1 Outer membrane protein (OmpH-like) HEAT PF02985.17 EGC39805.1 - 0.031 14.3 0.0 18 5.7 0.0 4.7 5 0 0 5 5 5 0 HEAT repeat Gti1_Pac2 PF09729.4 EGC39806.1 - 0.44 10.3 6.2 1.4 8.7 0.8 2.6 2 0 0 2 2 2 0 Gti1/Pac2 family Tetraspannin PF00335.15 EGC39806.1 - 2.4 7.3 9.9 21 4.3 2.6 3.4 3 0 0 3 3 3 0 Tetraspanin family ATAD4 PF15321.1 EGC39806.1 - 2.4 9.1 13.6 0.8 10.7 3.7 3.0 2 0 0 2 2 2 0 ATPase family AAA domain containing 4 DUF4526 PF15029.1 EGC39806.1 - 5.6 6.4 8.0 6.1 6.3 4.2 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF4526) DEAD PF00270.24 EGC39807.1 - 9.9e-40 135.7 0.1 2.3e-38 131.3 0.0 2.3 2 0 0 2 2 2 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC39807.1 - 4.6e-20 71.2 0.0 6.2e-19 67.6 0.0 2.6 2 0 0 2 2 2 1 Helicase conserved C-terminal domain Shikimate_DH PF01488.15 EGC39807.1 - 0.0082 16.2 0.1 0.29 11.2 0.0 2.7 2 0 0 2 2 2 1 Shikimate / quinate 5-dehydrogenase VIT_2 PF13757.1 EGC39808.1 - 0.081 12.3 0.0 0.17 11.3 0.0 1.5 1 0 0 1 1 1 0 Vault protein inter-alpha-trypsin domain F-box-like PF12937.2 EGC39808.1 - 0.11 12.2 0.0 1.1 9.0 0.0 2.4 2 0 0 2 2 2 0 F-box-like Peptidase_C1 PF00112.18 EGC39809.1 - 4.7e-58 196.6 2.3 4.7e-58 196.6 1.6 2.4 2 0 0 2 2 2 1 Papain family cysteine protease CBM49 PF09478.5 EGC39809.1 - 9.7e-40 134.5 15.2 3.8e-20 71.7 1.4 3.2 3 0 0 3 3 3 2 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.7 EGC39809.1 - 2.1e-12 47.1 9.0 8.9e-12 45.0 6.2 2.2 1 0 0 1 1 1 1 Cathepsin propeptide inhibitor domain (I29) TonB_2 PF13103.1 EGC39809.1 - 0.0018 18.2 0.3 3.4 7.7 0.0 2.7 2 0 0 2 2 2 2 TonB C terminal Vps4_C PF09336.5 EGC39809.1 - 0.054 13.3 0.1 16 5.4 0.0 2.4 2 0 0 2 2 2 0 Vps4 C terminal oligomerisation domain DUF4219 PF13961.1 EGC39809.1 - 0.25 10.7 2.1 8.1 5.9 0.1 2.7 2 0 0 2 2 2 0 Domain of unknown function (DUF4219) DUF1180 PF06679.7 EGC39809.1 - 3.2 7.6 4.9 24 4.8 0.0 2.8 3 0 0 3 3 3 0 Protein of unknown function (DUF1180) Peptidase_C1 PF00112.18 EGC39810.1 - 2.1e-50 171.6 2.8 5.2e-40 137.6 0.9 3.3 2 1 1 3 3 3 2 Papain family cysteine protease CBM49 PF09478.5 EGC39810.1 - 1.8e-20 72.8 1.9 5.9e-20 71.1 1.3 1.9 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 Inhibitor_I29 PF08246.7 EGC39810.1 - 6.8e-12 45.4 11.7 7.8e-12 45.2 6.3 2.6 2 0 0 2 2 2 1 Cathepsin propeptide inhibitor domain (I29) Peptidase_C1_2 PF03051.10 EGC39810.1 - 5.6e-05 21.8 6.9 0.00044 18.8 0.1 3.1 3 0 0 3 3 3 2 Peptidase C1-like family CBM_2 PF00553.14 EGC39810.1 - 0.019 15.0 0.8 0.047 13.7 0.1 2.0 2 0 0 2 2 2 0 Cellulose binding domain HAUS6_N PF14661.1 EGC39810.1 - 0.11 11.8 6.0 0.2 11.0 3.7 1.6 2 0 0 2 2 2 0 HAUS augmin-like complex subunit 6 N-terminus TALPID3 PF15324.1 EGC39810.1 - 4.5 4.5 9.5 0.1 9.9 0.6 1.9 2 0 0 2 2 2 0 Hedgehog signalling target Tom22 PF04281.8 EGC39810.1 - 9.9 5.6 9.4 23 4.4 6.5 1.6 1 0 0 1 1 1 0 Mitochondrial import receptor subunit Tom22 NmrA PF05368.8 EGC39811.1 - 3.6e-56 190.0 0.1 4.4e-56 189.7 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC39811.1 - 4.2e-08 33.3 0.0 5.9e-08 32.9 0.0 1.2 1 0 0 1 1 1 1 NADH(P)-binding Lsm_interact PF05391.6 EGC39811.1 - 0.058 12.8 0.7 7.9 6.1 0.8 2.4 2 0 0 2 2 2 0 Lsm interaction motif PBS_linker_poly PF00427.16 EGC39811.1 - 0.095 12.3 0.6 0.28 10.8 0.1 2.1 2 0 0 2 2 2 0 Phycobilisome Linker polypeptide Glyco_hydro_47 PF01532.15 EGC39812.1 - 2.3e-127 425.3 0.0 3.2e-127 424.9 0.0 1.2 1 0 0 1 1 1 1 Glycosyl hydrolase family 47 Utp14 PF04615.8 EGC39812.1 - 5.7 4.9 31.0 7.7 4.5 21.5 1.1 1 0 0 1 1 1 0 Utp14 protein SprA-related PF12118.3 EGC39813.1 - 0.004 16.5 43.0 0.0054 16.1 29.8 1.3 1 0 0 1 1 1 1 SprA-related family DUF605 PF04652.11 EGC39813.1 - 0.0056 16.1 34.6 0.0061 16.0 24.0 1.1 1 0 0 1 1 1 1 Vta1 like eIF-3_zeta PF05091.7 EGC39813.1 - 0.22 10.1 35.5 0.26 9.8 24.2 1.4 1 1 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Utp14 PF04615.8 EGC39813.1 - 0.48 8.5 34.6 0.57 8.2 24.0 1.0 1 0 0 1 1 1 0 Utp14 protein TFIIA PF03153.8 EGC39813.1 - 8.2 6.2 50.8 10 5.9 35.2 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit SQS_PSY PF00494.14 EGC39814.1 - 3.3e-40 138.0 0.0 4e-40 137.7 0.0 1.1 1 0 0 1 1 1 1 Squalene/phytoene synthase CH PF00307.26 EGC39815.1 - 7.3e-33 112.8 9.8 2.1e-17 63.1 0.1 4.0 3 0 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC39815.1 - 0.0092 15.6 0.0 0.053 13.1 0.0 2.4 1 0 0 1 1 1 1 CAMSAP CH domain Kelch_4 PF13418.1 EGC39816.1 - 3.1e-41 138.8 12.5 3.1e-10 39.6 0.1 6.5 6 0 0 6 6 6 6 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC39816.1 - 3.5e-39 132.0 5.0 7e-09 35.6 0.0 8.0 7 0 0 7 7 7 6 Galactose oxidase, central domain Kelch_6 PF13964.1 EGC39816.1 - 6.7e-39 130.4 14.9 2.5e-09 36.8 0.0 7.0 5 2 2 7 7 7 6 Kelch motif Kelch_1 PF01344.20 EGC39816.1 - 9.7e-36 121.0 7.5 3e-08 33.0 0.0 6.8 6 0 0 6 6 6 5 Kelch motif Kelch_5 PF13854.1 EGC39816.1 - 9.3e-30 102.0 2.4 6.8e-05 22.7 0.0 6.3 6 0 0 6 6 6 5 Kelch motif Kelch_2 PF07646.10 EGC39816.1 - 1.4e-28 97.5 11.1 1.4e-08 34.1 0.1 6.9 6 1 0 6 6 6 5 Kelch motif F-box-like PF12937.2 EGC39816.1 - 8.7e-07 28.5 0.1 2.4e-06 27.1 0.0 1.8 2 0 0 2 2 2 1 F-box-like F-box PF00646.28 EGC39816.1 - 0.00017 21.1 0.0 0.00041 19.9 0.0 1.7 1 0 0 1 1 1 1 F-box domain Cnd2 PF05786.9 EGC39817.1 - 4.9e-126 422.0 53.5 4.9e-126 422.0 37.1 2.1 1 1 1 2 2 2 1 Condensin complex subunit 2 Dicty_CAR PF05462.6 EGC39818.1 - 1.2e-12 47.3 9.2 1.2e-12 47.3 6.4 1.8 2 0 0 2 2 2 1 Slime mold cyclic AMP receptor Frizzled PF01534.12 EGC39818.1 - 6.3e-05 21.9 13.3 9e-05 21.4 9.2 1.3 1 0 0 1 1 1 1 Frizzled/Smoothened family membrane region DUF4117 PF13491.1 EGC39818.1 - 0.0033 16.8 4.4 0.0033 16.8 3.0 2.6 4 0 0 4 4 4 1 Domain of unknown function (DUF4117) DUF202 PF02656.10 EGC39818.1 - 5.6 7.2 8.3 5.6 7.2 0.4 3.9 3 1 0 3 3 3 0 Domain of unknown function (DUF202) DUF3611 PF12263.3 EGC39818.1 - 9.8 5.5 9.4 17 4.7 0.7 3.4 3 0 0 3 3 3 0 Protein of unknown function (DUF3611) DUF418 PF04235.7 EGC39819.1 - 0.0097 15.5 0.8 0.0097 15.5 0.5 2.7 2 1 2 4 4 4 1 Protein of unknown function (DUF418) Smr PF01713.16 EGC39820.1 - 3.6e-13 49.5 0.0 6.8e-13 48.6 0.0 1.5 1 0 0 1 1 1 1 Smr domain FUN14 PF04930.10 EGC39820.1 - 0.027 14.7 0.6 0.17 12.1 0.4 2.0 1 1 0 1 1 1 0 FUN14 family DUF2115 PF09888.4 EGC39820.1 - 0.038 14.0 0.6 0.046 13.8 0.4 1.2 1 0 0 1 1 1 0 Uncharacterized protein conserved in archaea (DUF2115) IncA PF04156.9 EGC39820.1 - 0.097 12.2 0.4 0.34 10.4 0.0 2.0 3 0 0 3 3 3 0 IncA protein DUF3529 PF12046.3 EGC39820.1 - 0.15 11.0 1.0 17 4.3 0.0 2.9 2 1 1 3 3 3 0 Protein of unknown function (DUF3529) DUF3781 PF12636.2 EGC39820.1 - 0.84 9.6 4.2 1.2 9.1 0.4 2.4 1 1 1 2 2 2 0 Protein of unknown function (DUF3781) DUSP PF06337.7 EGC39821.1 - 5.2e-11 42.8 0.9 5.2e-11 42.8 0.6 5.8 4 3 1 5 5 5 1 DUSP domain RhoGEF PF00621.15 EGC39822.1 - 1.4e-53 181.4 3.8 1.4e-53 181.4 2.6 2.0 2 0 0 2 2 2 1 RhoGEF domain FYVE PF01363.16 EGC39822.1 - 4.4e-21 74.5 11.2 1e-20 73.3 7.8 1.7 1 0 0 1 1 1 1 FYVE zinc finger PH PF00169.24 EGC39822.1 - 8.5e-11 41.9 1.2 2.2e-10 40.6 0.8 1.8 1 0 0 1 1 1 1 PH domain PH_11 PF15413.1 EGC39822.1 - 5.8 7.2 9.4 7.7 6.8 2.2 3.2 3 1 0 3 3 3 0 Pleckstrin homology domain Cullin PF00888.17 EGC39823.1 - 2.7e-202 673.4 20.7 4.2e-202 672.8 14.3 1.3 1 0 0 1 1 1 1 Cullin family Cullin_Nedd8 PF10557.4 EGC39823.1 - 1.1e-28 98.8 6.1 3.9e-28 97.0 4.3 2.0 1 0 0 1 1 1 1 Cullin protein neddylation domain MIT PF04212.13 EGC39823.1 - 0.077 12.8 1.8 0.74 9.7 0.2 2.7 2 0 0 2 2 2 0 MIT (microtubule interacting and transport) domain NAGLU PF05089.7 EGC39824.1 - 2.6e-135 450.4 11.0 3.8e-135 449.9 7.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain NAGLU_C PF12972.2 EGC39824.1 - 9.3e-68 228.4 0.9 1.3e-67 228.0 0.6 1.2 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain NAGLU_N PF12971.2 EGC39824.1 - 1.5e-15 56.5 0.1 3.1e-15 55.6 0.0 1.5 1 0 0 1 1 1 1 Alpha-N-acetylglucosaminidase (NAGLU) N-terminal domain Pax2_C PF12403.3 EGC39824.1 - 0.019 14.6 0.0 0.05 13.2 0.0 1.7 1 0 0 1 1 1 0 Paired-box protein 2 C terminal SAGA-Tad1 PF12767.2 EGC39825.1 - 4e-30 105.3 2.8 4e-30 105.3 1.9 2.2 2 0 0 2 2 2 1 Transcriptional regulator of RNA polII, SAGA, subunit VWA_3 PF13768.1 EGC39827.1 - 9.8e-28 96.8 0.0 1.6e-27 96.1 0.0 1.4 1 0 0 1 1 1 1 von Willebrand factor type A domain VIT PF08487.5 EGC39827.1 - 2.5e-19 69.1 0.2 5.6e-19 67.9 0.2 1.6 1 0 0 1 1 1 1 Vault protein inter-alpha-trypsin domain VWA PF00092.23 EGC39827.1 - 1.7e-13 50.7 0.0 4.4e-13 49.3 0.0 1.7 1 0 0 1 1 1 1 von Willebrand factor type A domain VWA_2 PF13519.1 EGC39827.1 - 2e-10 41.0 0.0 4.1e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 von Willebrand factor type A domain vWA-TerF-like PF10138.4 EGC39827.1 - 1.3e-06 28.4 0.0 2.6e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 vWA found in TerF C terminus VIT_2 PF13757.1 EGC39827.1 - 0.0091 15.4 0.1 0.044 13.2 0.0 2.1 2 0 0 2 2 2 1 Vault protein inter-alpha-trypsin domain Prenyltrans_1 PF13243.1 EGC39827.1 - 0.084 12.8 0.1 1.2 9.1 0.0 2.8 3 0 0 3 3 3 0 Prenyltransferase-like VWA_CoxE PF05762.9 EGC39827.1 - 0.11 11.6 0.0 1.1 8.2 0.0 2.1 2 0 0 2 2 2 0 VWA domain containing CoxE-like protein Rubella_Capsid PF05750.6 EGC39827.1 - 0.9 8.8 3.3 1.5 8.1 2.3 1.2 1 0 0 1 1 1 0 Rubella capsid protein EGF_2 PF07974.8 EGC39828.1 - 0.0017 18.4 45.3 0.12 12.5 4.9 3.9 3 0 0 3 3 3 3 EGF-like domain Laminin_EGF PF00053.19 EGC39828.1 - 0.0018 18.1 34.1 0.29 11.0 6.2 3.8 2 1 1 3 3 3 3 Laminin EGF-like (Domains III and V) hEGF PF12661.2 EGC39828.1 - 0.019 14.9 1.3 0.019 14.9 0.9 2.5 2 0 0 2 2 2 0 Human growth factor-like EGF DUF1163 PF06651.6 EGC39828.1 - 0.043 13.3 0.0 0.1 12.1 0.0 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1163) LRR_1 PF00560.28 EGC39828.1 - 2.1 8.7 8.5 4.4 7.7 0.0 5.9 5 0 0 5 5 5 0 Leucine Rich Repeat DUF2723 PF11028.3 EGC39829.1 - 7.6e-45 152.5 12.3 1.5e-44 151.6 8.5 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF2723) DUF456 PF04306.8 EGC39829.1 - 0.041 13.9 7.2 0.045 13.7 0.2 2.7 2 0 0 2 2 2 0 Protein of unknown function (DUF456) vATP-synt_E PF01991.13 EGC39830.1 - 1.7e-68 229.8 7.4 2e-68 229.6 5.1 1.0 1 0 0 1 1 1 1 ATP synthase (E/31 kDa) subunit ATP-synt_B PF00430.13 EGC39830.1 - 4.2 7.1 17.1 8.2 6.2 6.8 2.6 1 1 1 2 2 2 0 ATP synthase B/B' CF(0) UPF0139 PF03669.8 EGC39831.1 - 4.6e-19 67.8 0.3 5.2e-19 67.6 0.2 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0139) MadM PF03818.8 EGC39831.1 - 0.017 14.6 0.8 0.026 14.0 0.5 1.4 1 1 0 1 1 1 0 Malonate/sodium symporter MadM subunit DUF4401 PF14351.1 EGC39831.1 - 0.031 13.2 1.7 0.04 12.9 1.2 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4401) Pyridoxal_deC PF00282.14 EGC39832.1 - 1.3e-22 79.7 0.0 4.4e-14 51.7 0.0 3.3 3 0 0 3 3 3 3 Pyridoxal-dependent decarboxylase conserved domain RLL PF10036.4 EGC39833.1 - 1.6e-52 178.4 18.2 2.1e-52 178.0 12.6 1.1 1 0 0 1 1 1 1 Putative carnitine deficiency-associated protein DUF1390 PF07150.6 EGC39833.1 - 6.4 6.0 12.8 0.12 11.6 2.5 2.1 2 0 0 2 2 2 0 Protein of unknown function (DUF1390) DUF1697 PF08002.6 EGC39834.1 - 1.4e-19 70.5 0.1 1.9e-19 70.0 0.1 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) FNIP PF05725.7 EGC39836.1 - 1.6e-59 197.5 59.9 6.7e-14 51.5 1.1 8.6 4 2 2 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 EGC39836.1 - 0.0057 16.3 22.6 0.11 12.2 0.5 4.5 3 2 1 4 4 4 4 Leucine rich repeats (6 copies) Peptidase_S24 PF00717.18 EGC39836.1 - 0.09 12.4 1.7 0.094 12.3 0.1 1.9 2 0 0 2 2 2 0 Peptidase S24-like Tecti-min-caps PF09300.5 EGC39836.1 - 0.68 9.7 5.7 28 4.5 0.0 4.7 5 1 1 6 6 6 0 Tectiviridae, minor capsid Acetyltransf_2 PF00797.12 EGC39837.1 - 6.3e-25 88.1 0.0 7.3e-25 87.9 0.0 1.1 1 0 0 1 1 1 1 N-acetyltransferase Lyase_aromatic PF00221.14 EGC39838.1 - 1.4e-150 501.8 0.0 1.7e-150 501.6 0.0 1.0 1 0 0 1 1 1 1 Aromatic amino acid lyase CAP18_C PF12153.3 EGC39838.1 - 0.035 13.7 1.3 0.071 12.7 0.9 1.5 1 0 0 1 1 1 0 LPS binding domain of CAP18 (C terminal) NmrA PF05368.8 EGC39839.1 - 1.1e-20 73.9 0.1 1.3e-20 73.6 0.1 1.1 1 0 0 1 1 1 1 NmrA-like family NAD_binding_10 PF13460.1 EGC39839.1 - 2.9e-09 37.2 0.0 4.9e-09 36.4 0.0 1.4 1 0 0 1 1 1 1 NADH(P)-binding Epimerase PF01370.16 EGC39839.1 - 3.1e-05 23.5 0.0 0.00013 21.4 0.0 2.2 1 1 0 1 1 1 1 NAD dependent epimerase/dehydratase family 3Beta_HSD PF01073.14 EGC39839.1 - 5.9e-05 21.8 0.0 0.00015 20.5 0.0 1.6 1 1 0 1 1 1 1 3-beta hydroxysteroid dehydrogenase/isomerase family TrkA_N PF02254.13 EGC39839.1 - 0.0011 18.8 0.0 0.0023 17.9 0.0 1.5 1 0 0 1 1 1 1 TrkA-N domain NAD_binding_4 PF07993.7 EGC39839.1 - 0.0038 16.1 0.0 0.0061 15.5 0.0 1.4 1 0 0 1 1 1 1 Male sterility protein Helicase_C_3 PF13625.1 EGC39840.1 - 5.7e-28 97.2 0.0 1.5e-27 95.8 0.0 1.7 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC39840.1 - 9.6e-12 45.0 0.7 2.4e-11 43.7 0.0 2.0 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit Helicase_C PF00271.26 EGC39840.1 - 8.3e-10 38.3 0.1 3.3e-09 36.4 0.0 2.1 2 0 0 2 2 2 1 Helicase conserved C-terminal domain SNF2_N PF00176.18 EGC39840.1 - 1.5e-08 33.8 0.3 4.1e-08 32.3 0.1 1.6 1 1 1 2 2 2 1 SNF2 family N-terminal domain RasGEF PF00617.14 EGC39841.1 - 2.1e-57 193.9 4.2 2.1e-57 193.9 2.9 2.8 2 0 0 2 2 2 1 RasGEF domain RasGEF_N PF00618.15 EGC39841.1 - 6.2e-07 29.4 3.0 6.2e-07 29.4 2.1 5.0 5 2 0 5 5 5 1 RasGEF N-terminal motif Pkinase PF00069.20 EGC39842.1 - 1.6e-50 171.7 0.1 3.6e-50 170.5 0.0 1.6 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39842.1 - 1.5e-37 129.0 0.0 2e-37 128.6 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC39842.1 - 0.007 16.1 0.0 0.13 11.9 0.0 2.1 1 1 1 2 2 2 1 Phosphotransferase enzyme family AAA_12 PF13087.1 EGC39843.1 - 8.5e-41 139.5 0.3 8.5e-41 139.5 0.2 2.4 3 0 0 3 3 3 1 AAA domain AAA_11 PF13086.1 EGC39843.1 - 9.8e-24 84.2 5.5 9.8e-24 84.2 3.8 4.2 2 2 0 2 2 2 1 AAA domain SAM_1 PF00536.25 EGC39843.1 - 2.8e-07 30.6 1.5 1e-06 28.8 0.1 2.6 3 0 0 3 3 3 1 SAM domain (Sterile alpha motif) AAA_30 PF13604.1 EGC39843.1 - 1.4e-06 28.0 0.0 0.0033 17.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain AAA_19 PF13245.1 EGC39843.1 - 5.6e-05 22.8 0.0 0.00013 21.6 0.0 1.5 1 0 0 1 1 1 1 Part of AAA domain SAM_2 PF07647.12 EGC39843.1 - 0.00016 21.4 0.1 0.00042 20.0 0.1 1.8 1 0 0 1 1 1 1 SAM domain (Sterile alpha motif) AAA_22 PF13401.1 EGC39843.1 - 0.0041 17.2 0.2 0.1 12.7 0.0 3.1 3 0 0 3 3 3 1 AAA domain AAA_16 PF13191.1 EGC39843.1 - 0.021 14.7 0.0 0.058 13.3 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain AAA_25 PF13481.1 EGC39843.1 - 0.18 11.2 0.0 0.44 9.9 0.0 1.6 1 0 0 1 1 1 0 AAA domain LRR_6 PF13516.1 EGC39844.1 - 2.7e-06 26.8 12.0 0.034 14.2 0.0 5.6 6 0 0 6 6 6 3 Leucine Rich repeat Racemase_4 PF13615.1 EGC39844.1 - 0.1 12.8 0.9 0.38 11.0 0.1 2.2 1 1 1 2 2 2 0 Putative alanine racemase LRR_1 PF00560.28 EGC39844.1 - 0.12 12.5 7.2 39 4.8 0.0 5.5 5 1 0 5 5 5 0 Leucine Rich Repeat PP2C PF00481.16 EGC39845.1 - 1.6e-63 214.4 0.0 1.9e-63 214.2 0.0 1.0 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGC39845.1 - 2.5e-05 23.7 0.0 0.0004 19.8 0.0 2.3 1 1 0 1 1 1 1 Protein phosphatase 2C 2-oxoacid_dh PF00198.18 EGC39845.1 - 0.0086 15.3 0.0 0.012 14.8 0.0 1.2 1 0 0 1 1 1 1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) zf-RING_2 PF13639.1 EGC39846.1 - 2e-13 49.9 6.0 3.1e-13 49.2 4.2 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC39846.1 - 1.8e-07 31.0 6.5 3.2e-07 30.2 4.5 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39846.1 - 2.2e-07 30.8 3.3 4.1e-07 30.0 2.3 1.4 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC39846.1 - 2.8e-07 30.0 7.2 4.8e-07 29.3 5.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39846.1 - 4.2e-07 29.5 8.3 6.5e-07 28.9 5.8 1.3 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC39846.1 - 1e-05 25.0 6.3 1.7e-05 24.4 4.3 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGC39846.1 - 0.00099 18.9 2.9 0.0019 18.0 2.0 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC39846.1 - 0.045 13.4 2.3 0.1 12.3 1.6 1.6 1 0 0 1 1 1 0 RING-type zinc-finger FANCL_C PF11793.3 EGC39846.1 - 0.23 11.4 5.3 0.53 10.2 3.7 1.6 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EGC39846.1 - 0.48 9.9 3.0 0.92 9.0 2.1 1.5 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_4 PF14570.1 EGC39846.1 - 1.9 8.1 7.9 3.5 7.3 5.5 1.4 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain RINGv PF12906.2 EGC39846.1 - 4.4 7.4 10.2 7.8 6.6 7.1 1.4 1 0 0 1 1 1 0 RING-variant domain PHD PF00628.24 EGC39846.1 - 4.5 7.0 9.4 7.5 6.3 6.5 1.4 1 0 0 1 1 1 0 PHD-finger RNB PF00773.14 EGC39847.1 - 1.1e-90 304.3 0.0 1.1e-90 304.3 0.0 3.9 2 1 1 4 4 4 1 RNB domain RhoGAP PF00620.22 EGC39848.1 - 1.6e-32 112.2 0.2 1.6e-32 112.2 0.2 2.3 2 0 0 2 2 2 1 RhoGAP domain BAR_2 PF10455.4 EGC39848.1 - 9e-06 24.8 17.2 9e-06 24.8 11.9 1.7 1 1 0 1 1 1 1 Bin/amphiphysin/Rvs domain for vesicular trafficking FliJ PF02050.11 EGC39848.1 - 0.04 13.9 17.7 0.027 14.5 2.7 2.6 1 1 1 2 2 2 0 Flagellar FliJ protein Cyt-b5 PF00173.23 EGC39849.1 - 9.3e-26 89.4 0.4 1e-25 89.3 0.3 1.0 1 0 0 1 1 1 1 Cytochrome b5-like Heme/Steroid binding domain MMR_HSR1 PF01926.18 EGC39851.1 - 9e-51 170.7 0.2 2.3e-24 85.5 0.0 2.2 2 0 0 2 2 2 2 50S ribosome-binding GTPase KH_dom-like PF14714.1 EGC39851.1 - 3.4e-22 78.1 1.4 7.1e-22 77.1 1.0 1.6 1 0 0 1 1 1 1 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal FeoB_N PF02421.13 EGC39851.1 - 4.3e-22 78.0 0.0 6.7e-11 41.6 0.0 2.3 2 0 0 2 2 2 2 Ferrous iron transport protein B GTP_EFTU PF00009.22 EGC39851.1 - 1.2e-19 70.4 0.1 1.4e-07 31.1 0.1 4.2 4 0 0 4 4 4 3 Elongation factor Tu GTP binding domain Miro PF08477.8 EGC39851.1 - 6.5e-18 65.3 0.1 1.3e-08 35.3 0.0 2.9 2 1 0 2 2 2 2 Miro-like protein Dynamin_N PF00350.18 EGC39851.1 - 1.4e-15 57.5 0.1 0.0016 18.2 0.0 4.2 4 0 0 4 4 4 4 Dynamin family AIG1 PF04548.11 EGC39851.1 - 6.8e-12 44.9 0.1 3e-05 23.2 0.1 2.3 2 0 0 2 2 2 2 AIG1 family DUF258 PF03193.11 EGC39851.1 - 3.7e-06 26.2 0.0 0.025 13.7 0.0 2.5 2 0 0 2 2 2 2 Protein of unknown function, DUF258 Arf PF00025.16 EGC39851.1 - 5.4e-06 25.7 0.0 2.2 7.5 0.0 4.2 4 0 0 4 4 4 1 ADP-ribosylation factor family Ras PF00071.17 EGC39851.1 - 1.5e-05 24.4 0.0 0.51 9.7 0.0 3.5 2 2 0 2 2 2 2 Ras family MobB PF03205.9 EGC39851.1 - 4.3e-05 23.2 0.0 0.25 11.0 0.0 2.7 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B SRPRB PF09439.5 EGC39851.1 - 6.3e-05 22.2 0.1 0.013 14.6 0.0 2.8 2 1 0 2 2 2 1 Signal recognition particle receptor beta subunit cobW PF02492.14 EGC39851.1 - 6.6e-05 22.4 0.5 2.4 7.5 0.0 3.9 3 1 0 4 4 4 1 CobW/HypB/UreG, nucleotide-binding domain Gtr1_RagA PF04670.7 EGC39851.1 - 8.9e-05 21.7 1.8 0.014 14.5 0.1 2.5 2 1 0 2 2 2 1 Gtr1/RagA G protein conserved region ArgK PF03308.11 EGC39851.1 - 9.9e-05 21.2 0.1 2.8 6.6 0.0 3.6 3 1 1 4 4 4 2 ArgK protein Guanylate_kin PF00625.16 EGC39851.1 - 0.00019 20.9 0.3 0.044 13.2 0.1 2.6 2 1 0 2 2 2 1 Guanylate kinase ABC_tran PF00005.22 EGC39851.1 - 0.00022 21.5 0.6 0.36 11.1 0.0 2.7 1 1 1 2 2 2 2 ABC transporter AAA_17 PF13207.1 EGC39851.1 - 0.00032 21.5 0.1 0.17 12.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_18 PF13238.1 EGC39851.1 - 0.00068 19.9 0.1 0.51 10.6 0.0 2.7 2 1 0 2 2 2 1 AAA domain AAA_22 PF13401.1 EGC39851.1 - 0.00076 19.6 0.1 0.71 10.0 0.0 2.8 2 2 0 2 2 2 1 AAA domain NTPase_1 PF03266.10 EGC39851.1 - 0.0018 18.0 0.0 1 9.0 0.0 2.6 2 0 0 2 2 2 1 NTPase AAA_10 PF12846.2 EGC39851.1 - 0.0027 17.1 0.0 2.5 7.4 0.0 2.5 2 0 0 2 2 2 2 AAA-like domain RNA_helicase PF00910.17 EGC39851.1 - 0.0034 17.5 0.0 3.8 7.7 0.0 2.9 3 0 0 3 3 2 1 RNA helicase Arch_ATPase PF01637.13 EGC39851.1 - 0.0066 16.1 3.2 2.6 7.6 0.0 3.4 4 1 0 4 4 4 2 Archaeal ATPase AAA_14 PF13173.1 EGC39851.1 - 0.0072 16.2 0.1 3.2 7.6 0.0 3.0 3 0 0 3 3 3 1 AAA domain SRP54 PF00448.17 EGC39851.1 - 0.0074 15.7 0.0 0.19 11.1 0.0 2.3 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain FtsK_SpoIIIE PF01580.13 EGC39851.1 - 0.037 13.5 0.0 4.9 6.5 0.0 2.5 2 0 0 2 2 2 0 FtsK/SpoIIIE family AAA PF00004.24 EGC39851.1 - 0.041 14.0 0.2 14 5.9 0.0 3.2 2 2 0 2 2 2 0 ATPase family associated with various cellular activities (AAA) AAA_29 PF13555.1 EGC39851.1 - 0.042 13.3 0.0 6.4 6.3 0.0 2.5 2 0 0 2 2 2 0 P-loop containing region of AAA domain AAA_15 PF13175.1 EGC39851.1 - 0.091 11.7 0.1 0.091 11.7 0.1 3.0 2 1 0 2 2 2 0 AAA ATPase domain Zeta_toxin PF06414.7 EGC39851.1 - 0.094 11.7 0.0 0.23 10.5 0.0 1.6 2 0 0 2 2 1 0 Zeta toxin ATP-synt_ab PF00006.20 EGC39851.1 - 0.16 11.4 0.1 13 5.2 0.0 2.4 2 1 0 2 2 2 0 ATP synthase alpha/beta family, nucleotide-binding domain Abhydrolase_2 PF02230.11 EGC39852.1 - 0.067 12.6 0.0 0.14 11.5 0.0 1.5 1 0 0 1 1 1 0 Phospholipase/Carboxylesterase DUF3368 PF11848.3 EGC39852.1 - 0.074 12.6 0.0 0.14 11.7 0.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3368) INTS5_C PF14838.1 EGC39853.1 - 1.5e-16 59.9 0.1 1.5e-16 59.9 0.1 2.7 3 0 0 3 3 3 2 Integrator complex subunit 5 C-terminus Aldo_ket_red PF00248.16 EGC39854.1 - 1.8e-47 161.5 0.0 2.1e-47 161.3 0.0 1.0 1 0 0 1 1 1 1 Aldo/keto reductase family DUF59 PF01883.14 EGC39855.1 - 7.3e-06 25.8 0.0 2.6e-05 24.1 0.0 1.9 2 1 0 2 2 2 1 Domain of unknown function DUF59 FNIP PF05725.7 EGC39856.1 - 2e-46 155.6 67.9 4.9e-09 36.0 1.3 8.8 4 1 7 11 11 11 10 FNIP Repeat Ras PF00071.17 EGC39859.1 - 9.6e-43 145.3 0.0 1.1e-42 145.1 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39859.1 - 1.3e-19 70.7 0.0 2.2e-19 70.1 0.0 1.3 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39859.1 - 1.8e-15 56.6 0.0 2.6e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC39859.1 - 6.1e-07 28.8 0.0 9.5e-07 28.1 0.0 1.4 1 1 0 1 1 1 1 Gtr1/RagA G protein conserved region GTP_EFTU PF00009.22 EGC39859.1 - 3.1e-06 26.7 0.0 3.3e-05 23.4 0.0 2.0 1 1 1 2 2 2 1 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC39859.1 - 0.00089 19.2 0.0 0.0014 18.5 0.0 1.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase ATP_bind_1 PF03029.12 EGC39859.1 - 0.00092 18.8 0.2 0.0046 16.5 0.0 1.9 1 1 1 2 2 2 1 Conserved hypothetical ATP binding protein PduV-EutP PF10662.4 EGC39859.1 - 0.0012 18.3 0.0 0.0042 16.5 0.0 1.8 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation SRPRB PF09439.5 EGC39859.1 - 0.0052 16.0 0.0 0.023 13.9 0.0 1.9 2 0 0 2 2 2 1 Signal recognition particle receptor beta subunit AAA_14 PF13173.1 EGC39859.1 - 0.088 12.7 0.1 0.35 10.7 0.0 1.9 2 0 0 2 2 2 0 AAA domain Ribosomal_L23 PF00276.15 EGC39860.1 - 6.1e-09 35.6 3.3 4.8e-08 32.8 2.3 2.0 1 1 0 1 1 1 1 Ribosomal protein L23 VWA_2 PF13519.1 EGC39861.1 - 4.7e-08 33.3 0.1 1.1e-07 32.0 0.0 1.6 2 0 0 2 2 2 1 von Willebrand factor type A domain Ssl1 PF04056.9 EGC39861.1 - 1.5e-05 24.7 0.6 5.7e-05 22.8 0.1 2.0 3 0 0 3 3 3 1 Ssl1-like UIM PF02809.15 EGC39861.1 - 0.018 14.5 12.0 0.37 10.4 0.9 3.5 3 0 0 3 3 3 0 Ubiquitin interaction motif DUF4376 PF14301.1 EGC39861.1 - 0.089 12.9 1.8 0.79 9.8 0.1 2.5 2 0 0 2 2 2 0 Domain of unknown function (DUF4376) VGCC_beta4Aa_N PF12052.3 EGC39861.1 - 5.3 6.9 11.1 13 5.7 4.5 2.5 2 0 0 2 2 2 0 Voltage gated calcium channel subunit beta domain 4Aa N terminal DUF676 PF05057.9 EGC39862.1 - 9.3e-40 136.2 0.9 8.8e-34 116.6 0.0 2.6 3 0 0 3 3 3 2 Putative serine esterase (DUF676) PGAP1 PF07819.8 EGC39862.1 - 1.4e-07 31.3 0.0 2.9e-07 30.3 0.0 1.6 1 0 0 1 1 1 1 PGAP1-like protein Lipase_3 PF01764.20 EGC39862.1 - 7.1e-07 28.9 0.0 1.6e-06 27.8 0.0 1.6 1 0 0 1 1 1 1 Lipase (class 3) Abhydrolase_5 PF12695.2 EGC39862.1 - 0.00027 20.7 0.0 0.0004 20.1 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family LCAT PF02450.10 EGC39862.1 - 0.0032 16.5 0.5 0.0067 15.4 0.0 1.7 2 0 0 2 2 2 1 Lecithin:cholesterol acyltransferase Lipase_2 PF01674.13 EGC39862.1 - 0.034 13.4 0.1 0.11 11.8 0.1 1.8 1 1 0 1 1 1 0 Lipase (class 2) DUF915 PF06028.6 EGC39862.1 - 0.036 13.1 3.9 1.6 7.7 0.1 2.6 2 1 1 3 3 3 0 Alpha/beta hydrolase of unknown function (DUF915) Abhydrolase_6 PF12697.2 EGC39862.1 - 0.045 13.6 0.0 0.071 12.9 0.0 1.4 1 0 0 1 1 1 0 Alpha/beta hydrolase family Glutaredoxin PF00462.19 EGC39863.1 - 6e-20 70.9 0.0 9.6e-19 67.1 0.0 2.3 2 0 0 2 2 2 1 Glutaredoxin Thioredoxin PF00085.15 EGC39863.1 - 3.6e-15 55.5 0.1 6.8e-15 54.6 0.1 1.4 1 0 0 1 1 1 1 Thioredoxin Thioredoxin_2 PF13098.1 EGC39863.1 - 2.2e-05 24.6 0.2 0.00026 21.1 0.0 2.6 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC39863.1 - 5.3e-05 23.2 1.0 0.016 15.3 0.1 2.8 2 1 1 3 3 3 2 Thioredoxin-like Thioredoxin_6 PF13848.1 EGC39863.1 - 0.0042 16.9 0.8 0.0082 15.9 0.3 1.6 2 0 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_3 PF13192.1 EGC39863.1 - 0.0089 15.8 0.1 0.18 11.6 0.0 2.4 2 0 0 2 2 2 1 Thioredoxin domain HyaE PF07449.6 EGC39863.1 - 0.027 14.3 0.0 0.097 12.5 0.0 1.9 2 0 0 2 2 2 0 Hydrogenase-1 expression protein HyaE ArsC PF03960.10 EGC39863.1 - 0.078 13.0 0.0 2.1 8.4 0.0 2.3 2 0 0 2 2 2 0 ArsC family F-box-like PF12937.2 EGC39864.1 - 1.6e-08 34.1 0.3 3.5e-08 33.0 0.2 1.7 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC39864.1 - 9e-08 31.5 0.5 1.7e-07 30.6 0.3 1.5 1 0 0 1 1 1 1 F-box domain GSH-S_N PF02951.9 EGC39864.1 - 0.11 12.2 0.0 0.26 11.0 0.0 1.5 1 0 0 1 1 1 0 Prokaryotic glutathione synthetase, N-terminal domain PRKCSH PF07915.8 EGC39865.1 - 4.5e-13 49.8 0.7 4.5e-13 49.8 0.5 2.7 2 1 0 2 2 2 1 Glucosidase II beta subunit-like protein Euplotes_phero PF05842.6 EGC39865.1 - 4.1 7.7 14.0 2.8 8.2 7.9 1.9 2 0 0 2 2 2 0 Euplotes octocarinatus mating pheromone protein RabGAP-TBC PF00566.13 EGC39866.1 - 6.1e-54 182.7 1.5 6.1e-54 182.7 1.1 3.6 5 1 0 5 5 5 1 Rab-GTPase-TBC domain GRAM PF02893.15 EGC39866.1 - 4.9e-16 57.9 5.5 4.9e-09 35.5 1.5 3.9 5 0 0 5 5 5 2 GRAM domain Mito_carr PF00153.22 EGC39867.1 - 5.1e-77 253.7 3.0 1.4e-25 88.8 0.1 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein EphA2_TM PF14575.1 EGC39868.1 - 0.049 14.0 4.7 11 6.5 0.0 3.8 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF4064 PF13273.1 EGC39868.1 - 3.7 7.7 13.8 0.39 10.8 5.6 2.3 1 1 1 2 2 2 0 Protein of unknown function (DUF4064) Erf4 PF10256.4 EGC39869.1 - 0.00077 19.3 3.4 0.0022 17.8 1.4 2.5 1 1 1 2 2 2 1 Golgin subfamily A member 7/ERF4 family RNA_pol_Rpb4 PF03874.11 EGC39869.1 - 4 7.4 11.3 41 4.2 5.8 2.5 2 0 0 2 2 2 0 RNA polymerase Rpb4 Erf4 PF10256.4 EGC39870.1 - 0.0056 16.5 8.2 0.0083 15.9 3.2 2.5 2 1 0 2 2 2 1 Golgin subfamily A member 7/ERF4 family Phtf-FEM1B_bdg PF12129.3 EGC39870.1 - 1.9 7.7 12.7 0.29 10.4 1.1 2.2 2 0 0 2 2 2 0 Male germ-cell putative homeodomain transcription factor DUF607 PF04678.8 EGC39870.1 - 3.2 7.6 6.8 0.18 11.7 0.9 1.7 2 0 0 2 2 2 0 Protein of unknown function, DUF607 Pkinase_Tyr PF07714.12 EGC39871.1 - 3.9e-36 124.4 0.0 8.8e-36 123.2 0.0 1.7 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC39871.1 - 1.2e-35 122.9 0.0 2.5e-35 121.8 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain Arm PF00514.18 EGC39871.1 - 1e-16 60.0 12.4 0.1 12.4 0.0 10.0 10 0 0 10 10 10 4 Armadillo/beta-catenin-like repeat LRR_4 PF12799.2 EGC39871.1 - 4.2e-16 58.1 24.0 7.9e-05 22.1 0.7 6.1 2 1 4 6 6 6 5 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC39871.1 - 6.4e-11 41.8 19.2 7.4e-05 22.4 3.3 4.5 1 1 4 5 5 5 4 Leucine rich repeat HEAT_2 PF13646.1 EGC39871.1 - 1e-09 38.5 2.8 0.00091 19.4 0.3 5.0 3 1 0 4 4 4 2 HEAT repeats LRR_9 PF14580.1 EGC39871.1 - 1.1e-07 31.6 3.8 4.5e-06 26.3 0.3 3.1 1 1 2 3 3 3 1 Leucine-rich repeat LRR_6 PF13516.1 EGC39871.1 - 4.5e-05 23.0 14.5 0.084 12.9 0.0 6.6 5 1 0 5 5 5 1 Leucine Rich repeat LRR_1 PF00560.28 EGC39871.1 - 0.00055 19.6 18.3 5.7 7.3 0.4 7.5 5 1 1 6 6 6 1 Leucine Rich Repeat LRR_7 PF13504.1 EGC39871.1 - 0.0044 16.9 9.5 49 4.7 0.0 7.4 6 0 0 6 6 6 0 Leucine rich repeat CTNNBL PF08216.6 EGC39871.1 - 0.031 13.8 8.9 13 5.4 0.4 5.9 5 1 1 6 6 6 0 Catenin-beta-like, Arm-motif containing nuclear HEAT_EZ PF13513.1 EGC39871.1 - 0.053 14.0 0.1 27 5.4 0.0 4.4 5 0 0 5 5 5 0 HEAT-like repeat HEAT PF02985.17 EGC39871.1 - 0.24 11.5 5.6 31 5.0 0.0 5.1 5 0 0 5 5 4 0 HEAT repeat Methyltransf_3 PF01596.12 EGC39872.1 - 6.1e-64 214.8 1.0 7.7e-64 214.5 0.7 1.1 1 0 0 1 1 1 1 O-methyltransferase Methyltransf_24 PF13578.1 EGC39872.1 - 2.1e-12 47.7 0.1 4.2e-12 46.8 0.0 1.5 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39872.1 - 4.4e-09 36.9 0.1 9.5e-09 35.8 0.0 1.6 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC39872.1 - 2.1e-08 33.8 3.9 2.7e-08 33.5 1.3 2.0 2 0 0 2 2 2 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC39872.1 - 0.00028 21.2 0.2 0.0027 18.0 0.1 2.4 2 1 0 2 2 2 1 Methyltransferase domain Cons_hypoth95 PF03602.10 EGC39872.1 - 0.0012 18.2 0.1 0.0032 16.8 0.0 1.8 1 1 1 2 2 2 1 Conserved hypothetical protein 95 Methyltransf_26 PF13659.1 EGC39872.1 - 0.0063 16.5 0.0 0.0098 15.9 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_15 PF09445.5 EGC39872.1 - 0.0067 15.9 0.1 0.014 14.9 0.1 1.5 1 0 0 1 1 1 1 RNA cap guanine-N2 methyltransferase MTS PF05175.9 EGC39872.1 - 0.0075 15.6 0.0 0.012 15.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain DUF1366 PF07104.6 EGC39872.1 - 0.0099 15.4 0.3 0.29 10.7 0.1 2.5 2 0 0 2 2 2 1 Protein of unknown function (DUF1366) AFG1_ATPase PF03969.11 EGC39872.1 - 0.014 14.2 0.1 0.067 11.9 0.0 2.0 3 0 0 3 3 3 0 AFG1-like ATPase Methyltransf_11 PF08241.7 EGC39872.1 - 0.07 13.6 0.0 0.17 12.3 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain PCMT PF01135.14 EGC39872.1 - 0.14 11.6 0.0 0.24 10.8 0.0 1.4 1 0 0 1 1 1 0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) AMP-binding PF00501.23 EGC39873.1 - 6.5e-79 265.2 0.0 8.1e-79 264.9 0.0 1.0 1 0 0 1 1 1 1 AMP-binding enzyme AMP-binding_C PF13193.1 EGC39873.1 - 3.9e-13 50.1 0.0 1.1e-12 48.7 0.0 1.8 2 0 0 2 2 2 1 AMP-binding enzyme C-terminal domain Mob1_phocein PF03637.12 EGC39874.1 - 6.7e-77 257.0 0.1 7.9e-77 256.8 0.1 1.0 1 0 0 1 1 1 1 Mob1/phocein family TTL PF03133.10 EGC39875.1 - 9.9e-25 87.0 2.3 1.6e-24 86.3 1.6 1.3 1 0 0 1 1 1 1 Tubulin-tyrosine ligase family Bt_P21 PF05560.6 EGC39875.1 - 0.01 15.2 0.3 0.026 13.9 0.2 1.6 1 0 0 1 1 1 0 Bacillus thuringiensis P21 molecular chaperone protein ATPgrasp_YheCD PF14398.1 EGC39875.1 - 0.011 14.5 0.0 0.047 12.4 0.0 1.9 2 0 0 2 2 2 0 YheC/D like ATP-grasp ATP-grasp_4 PF13535.1 EGC39875.1 - 0.077 12.7 0.0 4.6 6.9 0.0 2.4 1 1 1 2 2 2 0 ATP-grasp domain DnaJ PF00226.26 EGC39876.1 - 8.2e-17 60.7 1.8 8.2e-17 60.7 1.3 2.4 2 0 0 2 2 2 1 DnaJ domain TPR_2 PF07719.12 EGC39876.1 - 0.00033 20.3 0.5 0.00094 18.9 0.4 1.9 1 0 0 1 1 1 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC39876.1 - 0.0009 18.8 0.1 0.0018 17.8 0.1 1.5 1 0 0 1 1 1 1 TPR repeat TPR_1 PF00515.23 EGC39876.1 - 0.013 15.1 0.2 0.031 13.8 0.2 1.7 1 0 0 1 1 1 0 Tetratricopeptide repeat TPR_12 PF13424.1 EGC39876.1 - 0.039 13.8 0.0 0.08 12.8 0.0 1.5 1 0 0 1 1 1 0 Tetratricopeptide repeat Ribosomal_S6e PF01092.14 EGC39877.1 - 3.4e-55 185.0 0.5 3.4e-55 185.0 0.3 1.5 2 0 0 2 2 2 1 Ribosomal protein S6e SpoIISA_toxin PF14171.1 EGC39878.1 - 0.007 15.6 0.5 0.012 14.9 0.4 1.3 1 0 0 1 1 1 1 Toxin SpoIISA, type II toxin-antitoxin system DUF1524 PF07510.6 EGC39878.1 - 0.01 15.6 0.6 0.019 14.8 0.4 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF1524) HNH_4 PF13395.1 EGC39878.1 - 0.031 13.8 0.2 0.1 12.2 0.1 2.0 1 1 0 1 1 1 0 HNH endonuclease HNH PF01844.18 EGC39878.1 - 0.056 13.3 0.2 0.17 11.7 0.0 1.9 2 0 0 2 2 2 0 HNH endonuclease Pox_polyA_pol_N PF12630.2 EGC39878.1 - 0.25 11.4 3.3 0.23 11.5 0.8 2.0 2 0 0 2 2 2 0 Poxvirus poly(A) polymerase N-terminal domain Zn-ribbon_8 PF09723.5 EGC39878.1 - 0.3 11.0 3.0 0.72 9.8 2.1 1.6 1 0 0 1 1 1 0 Zinc ribbon domain DUF947 PF06102.7 EGC39879.1 - 2.8e-38 131.3 27.9 2.8e-38 131.3 19.3 2.2 2 0 0 2 2 2 1 Domain of unknown function (DUF947) HHA PF05321.6 EGC39879.1 - 0.14 12.2 2.6 1.5 9.0 0.2 3.0 2 1 0 2 2 2 0 Haemolysin expression modulating protein Methyltransf_28 PF02636.12 EGC39880.1 - 1.6e-40 139.1 0.5 3.6e-40 137.9 0.0 1.8 2 0 0 2 2 2 1 Putative S-adenosyl-L-methionine-dependent methyltransferase FAM60A PF15396.1 EGC39880.1 - 7.6 6.2 8.1 18 4.9 5.6 1.6 1 0 0 1 1 1 0 Protein Family FAM60A ATG16 PF08614.6 EGC39882.1 - 0.0044 16.8 12.6 0.0097 15.7 8.7 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Phasin PF05597.6 EGC39882.1 - 0.0074 16.0 5.0 0.0074 16.0 3.5 1.5 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF904 PF06005.7 EGC39882.1 - 0.018 15.3 19.2 0.22 11.8 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 EGC39882.1 - 0.025 14.2 15.3 0.12 12.0 10.6 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2216 PF10226.4 EGC39882.1 - 0.07 12.6 11.8 0.091 12.2 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DivIVA PF05103.8 EGC39882.1 - 0.077 13.0 13.8 0.5 10.4 9.5 2.0 1 1 0 1 1 1 0 DivIVA protein Microtub_assoc PF07989.6 EGC39882.1 - 0.15 11.9 15.3 1.9 8.3 1.7 3.1 1 1 2 3 3 3 0 Microtubule associated RNase_P_pop3 PF08228.6 EGC39882.1 - 0.18 11.6 2.9 0.23 11.3 2.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 GAS PF13851.1 EGC39882.1 - 0.23 10.6 21.9 0.018 14.2 5.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EGC39882.1 - 0.23 11.4 18.1 2.3 8.2 0.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF4163 PF13739.1 EGC39882.1 - 0.36 11.6 2.3 0.27 12.0 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Z1 PF10593.4 EGC39882.1 - 0.38 9.9 4.2 0.47 9.6 2.9 1.1 1 0 0 1 1 1 0 Z1 domain IncA PF04156.9 EGC39882.1 - 0.42 10.1 12.3 0.48 9.9 8.5 1.1 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 EGC39882.1 - 0.61 9.8 9.7 0.041 13.6 1.5 2.0 1 1 1 2 2 2 0 Laminin Domain II CtIP_N PF10482.4 EGC39882.1 - 0.62 9.8 12.2 1 9.1 1.0 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.3 EGC39882.1 - 0.86 9.4 16.0 0.34 10.8 3.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EGC39882.1 - 0.92 9.3 18.4 0.19 11.5 1.4 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Zein-binding PF04576.10 EGC39882.1 - 1 9.5 12.6 4.3 7.5 1.3 2.4 1 1 1 2 2 2 0 Zein-binding Spc7 PF08317.6 EGC39882.1 - 1.1 7.8 18.3 1.3 7.6 12.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 EGC39882.1 - 2 8.2 9.2 1.5 8.6 1.4 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.3 EGC39882.1 - 2.8 7.1 12.5 4.5 6.4 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1875 PF08961.5 EGC39882.1 - 4.2 6.6 12.2 4.9 6.4 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF972 PF06156.8 EGC39882.1 - 4.3 7.7 14.7 5 7.5 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EGC39882.1 - 4.3 7.3 11.0 5.2 7.1 1.1 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.5 EGC39882.1 - 5.1 7.2 12.6 9.1 6.3 8.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 EGC39882.1 - 7.3 6.2 11.7 0.53 9.9 1.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region ATG16 PF08614.6 EGC39884.1 - 0.0044 16.8 12.6 0.0097 15.7 8.7 1.5 1 1 0 1 1 1 1 Autophagy protein 16 (ATG16) Phasin PF05597.6 EGC39884.1 - 0.0074 16.0 5.0 0.0074 16.0 3.5 1.5 1 1 0 1 1 1 1 Poly(hydroxyalcanoate) granule associated protein (phasin) DUF904 PF06005.7 EGC39884.1 - 0.018 15.3 19.2 0.22 11.8 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF904) CCDC155 PF14662.1 EGC39884.1 - 0.025 14.2 15.3 0.12 12.0 10.6 1.9 1 1 0 1 1 1 0 Coiled-coil region of CCDC155 DUF2216 PF10226.4 EGC39884.1 - 0.07 12.6 11.8 0.091 12.2 1.7 2.3 1 1 1 2 2 2 0 Uncharacterized conserved proteins (DUF2216) DivIVA PF05103.8 EGC39884.1 - 0.077 13.0 13.8 0.5 10.4 9.5 2.0 1 1 0 1 1 1 0 DivIVA protein Microtub_assoc PF07989.6 EGC39884.1 - 0.15 11.9 15.3 1.9 8.3 1.7 3.1 1 1 2 3 3 3 0 Microtubule associated RNase_P_pop3 PF08228.6 EGC39884.1 - 0.18 11.6 2.9 0.23 11.3 2.0 1.1 1 0 0 1 1 1 0 RNase P subunit Pop3 GAS PF13851.1 EGC39884.1 - 0.23 10.6 21.9 0.018 14.2 5.1 2.0 1 1 1 2 2 2 0 Growth-arrest specific micro-tubule binding bZIP_1 PF00170.16 EGC39884.1 - 0.23 11.4 18.1 2.3 8.2 0.5 3.4 3 0 0 3 3 3 0 bZIP transcription factor DUF4163 PF13739.1 EGC39884.1 - 0.36 11.6 2.3 0.27 12.0 0.7 1.6 1 1 1 2 2 2 0 Domain of unknown function (DUF4163) Z1 PF10593.4 EGC39884.1 - 0.38 9.9 4.2 0.47 9.6 2.9 1.1 1 0 0 1 1 1 0 Z1 domain IncA PF04156.9 EGC39884.1 - 0.42 10.1 12.3 0.48 9.9 8.5 1.1 1 0 0 1 1 1 0 IncA protein Laminin_II PF06009.7 EGC39884.1 - 0.61 9.8 9.7 0.041 13.6 1.5 2.0 1 1 1 2 2 2 0 Laminin Domain II CtIP_N PF10482.4 EGC39884.1 - 0.62 9.8 12.2 1 9.1 1.0 2.2 2 0 0 2 2 2 0 Tumour-suppressor protein CtIP N-terminal domain ADIP PF11559.3 EGC39884.1 - 0.86 9.4 16.0 0.34 10.8 3.7 2.1 1 1 1 2 2 2 0 Afadin- and alpha -actinin-Binding TMF_DNA_bd PF12329.3 EGC39884.1 - 0.92 9.3 18.4 0.19 11.5 1.4 3.1 1 1 2 3 3 3 0 TATA element modulatory factor 1 DNA binding Zein-binding PF04576.10 EGC39884.1 - 1 9.5 12.6 4.3 7.5 1.3 2.4 1 1 1 2 2 2 0 Zein-binding Spc7 PF08317.6 EGC39884.1 - 1.1 7.8 18.3 1.3 7.6 12.7 1.0 1 0 0 1 1 1 0 Spc7 kinetochore protein HALZ PF02183.13 EGC39884.1 - 2 8.2 9.2 1.5 8.6 1.4 3.1 2 1 1 3 3 3 0 Homeobox associated leucine zipper DUF3450 PF11932.3 EGC39884.1 - 2.8 7.1 12.5 4.5 6.4 2.4 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF3450) DUF1875 PF08961.5 EGC39884.1 - 4.2 6.6 12.2 4.9 6.4 2.2 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF1875) DUF972 PF06156.8 EGC39884.1 - 4.3 7.7 14.7 5 7.5 3.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF972) TSC22 PF01166.13 EGC39884.1 - 4.3 7.3 11.0 5.2 7.1 1.1 3.2 2 1 1 3 3 3 0 TSC-22/dip/bun family Fib_alpha PF08702.5 EGC39884.1 - 5.1 7.2 12.6 9.1 6.3 8.7 1.5 1 1 0 1 1 1 0 Fibrinogen alpha/beta chain family Nsp1_C PF05064.8 EGC39884.1 - 7.3 6.2 11.7 0.53 9.9 1.5 2.1 1 1 1 2 2 2 0 Nsp1-like C-terminal region OTU PF02338.14 EGC39885.1 - 2.4e-12 47.4 0.1 2.4e-12 47.4 0.0 2.1 2 0 0 2 2 2 1 OTU-like cysteine protease Peptidase_C65 PF10275.4 EGC39885.1 - 0.0036 16.6 10.6 1.8 7.8 0.0 3.0 2 1 1 3 3 3 1 Peptidase C65 Otubain Spt20 PF12090.3 EGC39885.1 - 0.004 16.5 4.7 0.0053 16.1 3.2 1.2 1 0 0 1 1 1 1 Spt20 family Gti1_Pac2 PF09729.4 EGC39885.1 - 0.024 14.5 0.2 0.026 14.3 0.1 1.2 1 0 0 1 1 1 0 Gti1/Pac2 family APC_CDC26 PF10471.4 EGC39885.1 - 0.024 15.3 15.4 0.054 14.2 10.7 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex APC subunit 1 DUF3371 PF11851.3 EGC39885.1 - 0.046 14.4 10.2 0.065 13.9 7.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3371) CBF PF03914.12 EGC39885.1 - 0.047 13.1 0.1 0.069 12.6 0.1 1.5 1 0 0 1 1 1 0 CBF/Mak21 family EPL1 PF10513.4 EGC39885.1 - 0.049 13.8 9.1 0.084 13.1 6.3 1.4 1 0 0 1 1 1 0 Enhancer of polycomb-like DUF3808 PF10300.4 EGC39885.1 - 0.055 12.0 2.2 0.077 11.5 1.5 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3808) PAT1 PF09770.4 EGC39885.1 - 0.074 11.2 26.8 0.093 10.9 18.6 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Nodulin PF02451.10 EGC39885.1 - 0.17 11.3 2.4 0.25 10.8 1.7 1.2 1 0 0 1 1 1 0 Nodulin DUF4175 PF13779.1 EGC39885.1 - 0.37 8.4 21.3 0.42 8.2 14.8 1.0 1 0 0 1 1 1 0 Domain of unknown function (DUF4175) DUF106 PF01956.11 EGC39885.1 - 0.41 10.1 2.7 0.53 9.7 1.9 1.2 1 0 0 1 1 1 0 Integral membrane protein DUF106 Peptidase_S49_N PF08496.5 EGC39885.1 - 0.42 10.3 4.6 0.69 9.6 3.2 1.3 1 0 0 1 1 1 0 Peptidase family S49 N-terminal LIM_bind PF01803.11 EGC39885.1 - 0.47 9.5 12.2 0.94 8.5 8.4 1.4 1 0 0 1 1 1 0 LIM-domain binding protein Suf PF05843.9 EGC39885.1 - 0.56 9.8 9.1 0.9 9.2 6.3 1.4 1 0 0 1 1 1 0 Suppressor of forked protein (Suf) Ndc1_Nup PF09531.5 EGC39885.1 - 1.2 7.4 5.4 1.5 7.1 3.8 1.1 1 0 0 1 1 1 0 Nucleoporin protein Ndc1-Nup FCP1_C PF09309.5 EGC39885.1 - 1.5 8.0 10.5 2.1 7.5 7.2 1.2 1 0 0 1 1 1 0 FCP1, C-terminal DUF4557 PF15101.1 EGC39885.1 - 1.7 8.4 11.8 2.6 7.8 8.2 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4557) AAA_23 PF13476.1 EGC39885.1 - 3.5 7.9 14.2 7.7 6.7 9.8 1.5 1 0 0 1 1 1 0 AAA domain RAB3GAP2_N PF14655.1 EGC39885.1 - 4.1 6.3 7.6 6.5 5.6 5.3 1.3 1 0 0 1 1 1 0 Rab3 GTPase-activating protein regulatory subunit N-terminus Band_3_cyto PF07565.8 EGC39885.1 - 5.2 6.4 10.5 7.4 6.0 7.2 1.4 1 1 0 1 1 1 0 Band 3 cytoplasmic domain RRM_2 PF04059.7 EGC39887.1 - 6.2e-24 83.8 1.7 1.6e-23 82.5 0.3 1.8 1 1 1 2 2 2 1 RNA recognition motif 2 RRM_1 PF00076.17 EGC39887.1 - 3.5e-06 26.5 0.0 6.4e-06 25.7 0.0 1.4 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC39887.1 - 0.00012 21.9 0.0 0.00048 20.0 0.0 1.8 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) 2Fe-2S_thioredx PF01257.14 EGC39887.1 - 0.0091 15.5 0.1 0.0095 15.5 0.1 1.1 1 0 0 1 1 1 1 Thioredoxin-like [2Fe-2S] ferredoxin Smg4_UPF3 PF03467.10 EGC39887.1 - 0.014 15.3 0.6 0.02 14.9 0.4 1.4 1 1 0 1 1 1 0 Smg-4/UPF3 family Cyclin_N PF00134.18 EGC39890.1 - 0.001 18.6 0.2 0.0019 17.7 0.2 1.5 1 0 0 1 1 1 1 Cyclin, N-terminal domain Cyclin PF08613.6 EGC39890.1 - 0.0083 16.5 1.1 0.0083 16.5 0.7 1.8 2 1 0 2 2 2 1 Cyclin DUF1649 PF07855.7 EGC39890.1 - 0.0086 15.7 0.2 0.016 14.8 0.1 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1649) Spore_IV_A PF09547.5 EGC39890.1 - 0.015 14.0 0.2 0.025 13.2 0.1 1.3 1 0 0 1 1 1 0 Stage IV sporulation protein A (spore_IV_A) Mpp10 PF04006.7 EGC39891.1 - 1.4e-83 281.3 149.5 7.5e-82 275.5 103.6 2.4 1 1 0 1 1 1 1 Mpp10 protein Ras PF00071.17 EGC39892.1 - 1.2e-22 80.0 0.0 1.7e-22 79.5 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39892.1 - 1.3e-07 32.1 0.0 2.3e-07 31.2 0.0 1.4 1 0 0 1 1 1 1 Miro-like protein zf-Di19 PF05605.7 EGC39894.1 - 3.1e-06 27.2 7.5 3.1e-06 27.2 5.2 2.8 2 1 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-H2C2_5 PF13909.1 EGC39894.1 - 0.0035 17.4 0.4 0.0035 17.4 0.2 4.2 4 1 0 4 4 4 1 C2H2-type zinc-finger domain zf-H2C2_2 PF13465.1 EGC39894.1 - 0.064 13.5 0.5 0.064 13.5 0.3 5.7 7 0 0 7 7 7 0 Zinc-finger double domain Thioredoxin PF00085.15 EGC39895.1 - 1.3e-28 98.6 0.3 6.5e-27 93.2 0.1 3.1 3 0 0 3 3 3 1 Thioredoxin Thioredoxin_6 PF13848.1 EGC39895.1 - 6.4e-12 45.6 9.4 4e-07 30.0 2.3 2.4 1 1 1 2 2 2 2 Thioredoxin-like domain Thioredoxin_8 PF13905.1 EGC39895.1 - 1.1e-05 25.4 3.5 0.0022 18.0 0.0 3.7 1 1 1 3 3 3 1 Thioredoxin-like Thioredoxin_2 PF13098.1 EGC39895.1 - 1.5e-05 25.1 1.4 0.00063 19.9 0.1 3.5 2 2 0 2 2 2 1 Thioredoxin-like domain Thioredoxin_4 PF13462.1 EGC39895.1 - 0.12 12.4 4.5 3.7 7.5 0.0 3.2 2 2 1 3 3 3 0 Thioredoxin FNIP PF05725.7 EGC39896.1 - 4.1e-171 554.7 75.9 2.8e-15 55.9 0.7 11.9 4 2 11 16 16 16 16 FNIP Repeat DDE_3 PF13358.1 EGC39897.1 - 0.00019 21.2 0.1 0.00035 20.3 0.1 1.5 1 0 0 1 1 1 1 DDE superfamily endonuclease DUF3893 PF13032.1 EGC39897.1 - 0.0043 17.1 0.2 0.006 16.7 0.1 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF3893) ketoacyl-synt PF00109.21 EGC39898.1 - 1.5e-60 204.8 0.0 2.3e-60 204.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC39898.1 - 2.4e-52 178.2 0.0 3.6e-52 177.6 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain NAD_binding_4 PF07993.7 EGC39898.1 - 7.2e-44 149.5 0.0 2.1e-43 148.0 0.0 1.8 2 0 0 2 2 2 1 Male sterility protein Ketoacyl-synt_C PF02801.17 EGC39898.1 - 4e-32 110.5 0.0 7.8e-32 109.6 0.0 1.5 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC39898.1 - 4.4e-26 91.6 0.0 9.5e-24 84.0 0.0 2.5 3 0 0 3 3 3 1 KR domain adh_short PF00106.20 EGC39898.1 - 6.2e-19 68.5 0.0 7.8e-16 58.4 0.0 2.7 2 0 0 2 2 2 2 short chain dehydrogenase PS-DH PF14765.1 EGC39898.1 - 1e-16 60.9 0.0 1.6e-16 60.3 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase Polysacc_synt_2 PF02719.10 EGC39898.1 - 7.7e-09 34.8 1.9 2.1e-05 23.5 0.2 2.4 2 0 0 2 2 2 2 Polysaccharide biosynthesis protein Epimerase PF01370.16 EGC39898.1 - 1.8e-07 30.8 0.1 1.9e-06 27.4 0.0 2.4 2 0 0 2 2 2 1 NAD dependent epimerase/dehydratase family ADH_N PF08240.7 EGC39898.1 - 1.6e-06 27.7 0.0 3.3e-06 26.8 0.0 1.5 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 EGC39898.1 - 3.4e-05 24.2 0.4 0.00029 21.2 0.0 3.0 2 1 1 3 3 2 1 Methyltransferase domain NAD_binding_10 PF13460.1 EGC39898.1 - 6.1e-05 23.0 0.0 0.0036 17.3 0.0 2.6 1 1 0 1 1 1 1 NADH(P)-binding ADH_zinc_N_2 PF13602.1 EGC39898.1 - 0.00012 22.9 0.0 0.0003 21.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGC39898.1 - 0.00017 21.7 0.3 0.00048 20.3 0.2 1.9 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC39898.1 - 0.0052 15.8 0.0 0.0094 14.9 0.0 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_23 PF13489.1 EGC39898.1 - 0.023 14.4 0.0 0.095 12.4 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Claudin_3 PF06653.6 EGC39900.1 - 0.02 14.6 0.4 0.02 14.6 0.3 1.5 2 0 0 2 2 2 0 Tight junction protein, Claudin-like EGF_2 PF07974.8 EGC39901.1 - 1.4e-06 28.3 31.5 0.00028 20.9 8.1 3.0 2 0 0 2 2 2 2 EGF-like domain hEGF PF12661.2 EGC39901.1 - 0.0055 16.7 16.4 0.031 14.3 1.2 3.1 3 0 0 3 3 3 2 Human growth factor-like EGF Laminin_EGF PF00053.19 EGC39901.1 - 0.044 13.7 22.7 0.6 10.0 6.2 3.0 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) DUF3529 PF12046.3 EGC39901.1 - 0.32 9.9 1.4 0.5 9.3 0.0 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF3529) LRR_1 PF00560.28 EGC39901.1 - 2 8.7 15.7 0.74 10.0 0.1 5.0 4 1 1 5 5 5 0 Leucine Rich Repeat LRR_6 PF13516.1 EGC39901.1 - 2.3 8.5 11.3 0.31 11.2 0.3 4.8 4 0 0 4 4 4 0 Leucine Rich repeat Brr6_like_C_C PF10104.4 EGC39902.1 - 1.1e-09 37.9 0.9 1.1e-09 37.9 0.6 3.4 3 1 1 4 4 4 2 Di-sulfide bridge nucleocytoplasmic transport domain 7TM_GPCR_Srw PF10324.4 EGC39902.1 - 0.00043 19.5 13.0 0.0082 15.2 2.8 2.5 2 0 0 2 2 2 2 Serpentine type 7TM GPCR chemoreceptor Srw DUF4448 PF14610.1 EGC39902.1 - 0.055 12.9 0.1 0.097 12.1 0.1 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF4448) 7tm_1 PF00001.16 EGC39902.1 - 0.082 12.0 11.6 4.5 6.3 8.1 2.1 1 1 0 1 1 1 0 7 transmembrane receptor (rhodopsin family) Ni_hydr_CYTB PF01292.15 EGC39902.1 - 0.17 11.2 1.9 5 6.4 0.1 2.2 2 1 0 2 2 2 0 Prokaryotic cytochrome b561 WBP-1 PF11669.3 EGC39902.1 - 0.25 11.4 2.9 0.84 9.7 0.2 2.5 1 1 2 3 3 3 0 WW domain-binding protein 1 DUF2615 PF11027.3 EGC39902.1 - 0.41 10.6 5.9 0.25 11.2 0.3 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF2615) Shisa PF13908.1 EGC39902.1 - 1.6 8.8 0.0 1.6 8.8 0.0 2.7 2 2 2 4 4 4 0 Wnt and FGF inhibitory regulator Scs3p PF10261.4 EGC39902.1 - 1.6 7.6 6.5 1.1 8.2 0.9 2.1 1 1 1 2 2 2 0 Inositol phospholipid synthesis and fat-storage-inducing TM zf-DHHC PF01529.15 EGC39902.1 - 5.6 6.3 19.0 2.9 7.2 6.8 2.3 2 0 0 2 2 2 0 DHHC palmitoyltransferase Mdv1 PF11542.3 EGC39903.1 - 0.16 11.9 1.4 3.2 7.7 0.1 2.6 2 0 0 2 2 2 0 Mitochondrial division protein 1 DUF1360 PF07098.6 EGC39905.1 - 0.012 15.2 0.1 0.025 14.3 0.0 1.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1360) PRA1 PF03208.14 EGC39905.1 - 0.046 13.0 0.0 0.064 12.5 0.0 1.2 1 0 0 1 1 1 0 PRA1 family protein EutQ PF06249.7 EGC39905.1 - 0.059 12.9 1.1 0.079 12.4 0.7 1.4 1 1 0 1 1 1 0 Ethanolamine utilisation protein EutQ FAM176 PF14851.1 EGC39905.1 - 0.07 12.8 0.0 0.093 12.4 0.0 1.2 1 0 0 1 1 1 0 FAM176 family Glycohydro_20b2 PF14845.1 EGC39905.1 - 3 8.5 6.0 2.7 8.6 3.2 1.5 1 1 1 2 2 2 0 beta-acetyl hexosaminidase like Herpes_UL49_5 PF05702.6 EGC39907.1 - 0.039 13.8 0.0 0.042 13.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein zf-RING_2 PF13639.1 EGC39908.1 - 5e-11 42.2 6.8 9e-11 41.4 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39908.1 - 2.1e-08 33.7 4.2 4.2e-08 32.7 2.9 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39908.1 - 2e-07 30.5 9.2 4.5e-07 29.4 6.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39908.1 - 6.7e-07 29.3 4.7 1.8e-06 27.9 3.3 1.8 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC39908.1 - 4.7e-06 26.5 9.1 9.1e-06 25.6 6.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39908.1 - 2.8e-05 23.7 6.6 6.1e-05 22.6 4.6 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC39908.1 - 0.0035 17.1 9.5 0.0091 15.8 6.6 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC39908.1 - 0.0036 17.1 1.5 0.0067 16.2 1.1 1.4 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.1 EGC39908.1 - 0.0046 16.6 3.8 0.029 14.0 2.6 2.4 2 0 0 2 2 2 1 Zinc-binding RING-finger Prok-RING_4 PF14447.1 EGC39908.1 - 0.031 13.8 4.4 0.09 12.3 3.0 1.8 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_4 PF14570.1 EGC39908.1 - 0.42 10.2 9.0 0.85 9.2 6.2 1.5 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain TFIIA PF03153.8 EGC39908.1 - 0.47 10.2 56.0 2 8.2 24.5 2.1 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit DUF1706 PF08020.6 EGC39909.1 - 0.062 12.8 0.2 0.074 12.5 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1706) API5 PF05918.6 EGC39910.1 - 1.1e-45 156.2 13.3 1.6e-45 155.6 9.3 1.2 1 0 0 1 1 1 1 Apoptosis inhibitory protein 5 (API5) WASH_WAHD PF11945.3 EGC39911.1 - 7.7e-55 186.2 1.2 9.9e-55 185.9 0.8 1.1 1 0 0 1 1 1 1 WAHD domain of WASH complex WH2 PF02205.15 EGC39911.1 - 0.00031 20.2 0.4 0.00061 19.3 0.3 1.5 1 0 0 1 1 1 1 WH2 motif PGA2 PF07543.7 EGC39911.1 - 3.7 7.3 9.7 1.5 8.5 0.3 2.5 2 0 0 2 2 2 0 Protein trafficking PGA2 TLP-20 PF06088.6 EGC39911.1 - 6.4 6.4 10.6 14 5.3 0.7 2.6 2 0 0 2 2 2 0 Nucleopolyhedrovirus telokin-like protein-20 (TLP20) SH3_9 PF14604.1 EGC39912.1 - 1.3e-15 56.7 0.2 2.2e-15 55.9 0.2 1.4 1 0 0 1 1 1 1 Variant SH3 domain SH3_1 PF00018.23 EGC39912.1 - 4.8e-14 51.4 0.0 9.3e-14 50.5 0.0 1.5 1 0 0 1 1 1 1 SH3 domain SH3_2 PF07653.12 EGC39912.1 - 2.9e-13 49.0 0.0 5.9e-13 48.0 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain Peroxin-13_N PF04088.8 EGC39912.1 - 1.9e-12 47.4 0.1 1.9e-12 47.4 0.1 3.1 2 1 0 3 3 3 1 Peroxin 13, N-terminal region Got1 PF04178.7 EGC39913.1 - 2.8e-18 66.1 12.7 3.1e-18 65.9 8.8 1.0 1 0 0 1 1 1 1 Got1/Sft2-like family ATP1G1_PLM_MAT8 PF02038.11 EGC39913.1 - 1.5 7.9 5.0 1.1 8.3 0.3 2.5 2 0 0 2 2 2 0 ATP1G1/PLM/MAT8 family DUF1129 PF06570.6 EGC39913.1 - 1.7 7.9 6.4 2.6 7.2 4.4 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1129) DUF308 PF03729.8 EGC39913.1 - 2.1 8.4 18.1 0.39 10.7 9.3 2.0 1 1 1 2 2 2 0 Short repeat of unknown function (DUF308) Anoctamin PF04547.7 EGC39913.1 - 3.3 6.2 5.3 1.3 7.5 0.2 2.0 1 1 1 2 2 2 0 Calcium-activated chloride channel DUF973 PF06157.6 EGC39913.1 - 8.4 5.2 19.0 4.2 6.2 7.6 2.0 1 1 1 2 2 2 0 Protein of unknown function (DUF973) DUF872 PF05915.7 EGC39913.1 - 9.5 6.1 10.4 1.3 8.8 3.4 2.2 1 1 1 2 2 2 0 Eukaryotic protein of unknown function (DUF872) Peptidase_S9 PF00326.16 EGC39915.1 - 1.1e-44 152.1 0.0 2.3e-44 151.1 0.0 1.5 1 0 0 1 1 1 1 Prolyl oligopeptidase family Peptidase_S9_N PF02897.10 EGC39915.1 - 2.6e-30 105.3 2.8 3.9e-30 104.7 2.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase, N-terminal beta-propeller domain Abhydrolase_1 PF00561.15 EGC39915.1 - 0.037 13.5 0.0 0.19 11.2 0.0 2.0 2 0 0 2 2 2 0 alpha/beta hydrolase fold Med12-LCEWAV PF12145.3 EGC39916.1 - 0.0072 14.8 1.4 0.0072 14.8 1.0 1.6 1 1 0 1 1 1 1 Eukaryotic Mediator 12 subunit domain Neur_chan_memb PF02932.11 EGC39916.1 - 0.92 9.3 4.4 1.1 9.0 3.0 1.0 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Chromo PF00385.19 EGC39918.1 - 1e-13 50.7 1.1 1.1e-13 50.6 0.8 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC39918.1 - 0.0032 17.1 0.4 0.0036 16.9 0.2 1.1 1 0 0 1 1 1 1 RNA binding activity-knot of a chromodomain DUF2791 PF10923.3 EGC39919.1 - 0.079 11.5 0.4 0.096 11.2 0.3 1.1 1 0 0 1 1 1 0 P-loop Domain of unknown function (DUF2791) BioW PF03744.8 EGC39919.1 - 0.085 12.2 0.4 0.093 12.1 0.3 1.1 1 0 0 1 1 1 0 6-carboxyhexanoate--CoA ligase GSCFA PF08885.6 EGC39920.1 - 0.0095 15.5 0.2 0.012 15.2 0.1 1.0 1 0 0 1 1 1 1 GSCFA family DUF3160 PF11369.3 EGC39920.1 - 0.035 12.4 0.9 0.035 12.4 0.7 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3160) Spuma_A9PTase PF03539.9 EGC39920.1 - 0.073 12.9 0.2 0.082 12.8 0.1 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) Chromo PF00385.19 EGC39921.1 - 5.1e-15 54.8 1.1 5.7e-15 54.7 0.8 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Aminotran_5 PF00266.14 EGC39922.1 - 6.1e-05 21.9 0.0 7.6e-05 21.6 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class-V Herpes_UL49_5 PF05702.6 EGC39922.1 - 0.046 13.6 0.0 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Herpesvirus UL49.5 envelope/tegument protein Pkinase PF00069.20 EGC39923.1 - 1.7e-23 83.1 0.2 1.7e-23 83.1 0.1 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39923.1 - 1.2e-11 44.1 0.0 2.3e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase DUF1084 PF06454.6 EGC39924.1 - 2.5e-11 43.1 23.3 5e-11 42.1 16.2 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) DUF1080 PF06439.6 EGC39925.1 - 0.08 12.8 0.0 0.086 12.7 0.0 1.1 1 0 0 1 1 1 0 Domain of Unknown Function (DUF1080) DASH_Dad4 PF08650.5 EGC39925.1 - 0.55 10.1 2.7 2.5 8.0 1.2 2.5 1 1 0 1 1 1 0 DASH complex subunit Dad4 DUF1084 PF06454.6 EGC39926.1 - 8.6e-16 57.8 22.8 1.8e-15 56.7 15.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) p450 PF00067.17 EGC39927.1 - 4.8e-84 282.5 0.2 5.4e-84 282.3 0.2 1.0 1 0 0 1 1 1 1 Cytochrome P450 Crinivirus_P26 PF07416.6 EGC39927.1 - 0.066 12.7 4.5 0.11 12.0 0.5 2.6 2 0 0 2 2 2 0 Crinivirus P26 protein p450 PF00067.17 EGC39928.1 - 2.9e-82 276.6 0.1 3.5e-82 276.3 0.1 1.1 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGC39929.1 - 4.2e-87 292.5 0.0 5e-87 292.3 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 p450 PF00067.17 EGC39930.1 - 2.4e-83 280.2 0.0 2.9e-83 279.9 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 Pkinase PF00069.20 EGC39931.1 - 8.5e-63 211.9 28.7 7.7e-22 77.6 0.2 4.0 4 0 0 4 4 4 3 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39931.1 - 8.2e-31 107.0 3.4 4.5e-12 45.5 0.0 3.3 3 0 0 3 3 3 3 Protein tyrosine kinase Kdo PF06293.9 EGC39931.1 - 2.5e-10 39.7 0.1 0.00075 18.6 0.1 2.8 3 0 0 3 3 3 2 Lipopolysaccharide kinase (Kdo/WaaP) family YrbL-PhoP_reg PF10707.4 EGC39931.1 - 5.2e-06 25.9 1.6 0.12 11.7 0.0 3.1 3 0 0 3 3 3 2 PhoP regulatory network protein YrbL APH PF01636.18 EGC39931.1 - 9.6e-05 22.2 0.0 2.1 8.0 0.0 3.9 3 2 2 5 5 5 2 Phosphotransferase enzyme family Cytochrome_C554 PF13435.1 EGC39931.1 - 0.38 10.8 0.1 0.8 9.7 0.1 1.5 1 0 0 1 1 1 0 Cytochrome c554 and c-prime GSCFA PF08885.6 EGC39932.1 - 0.011 15.2 0.1 0.013 15.0 0.1 1.1 1 0 0 1 1 1 0 GSCFA family Spuma_A9PTase PF03539.9 EGC39932.1 - 0.031 14.1 0.2 0.037 13.9 0.1 1.2 1 0 0 1 1 1 0 Spumavirus aspartic protease (A9) FadA PF09403.5 EGC39932.1 - 0.032 14.2 2.7 0.04 13.9 1.9 1.2 1 0 0 1 1 1 0 Adhesion protein FadA Nup88 PF10168.4 EGC39932.1 - 0.068 11.0 1.6 0.076 10.8 1.1 1.0 1 0 0 1 1 1 0 Nuclear pore component ABC2_membrane_3 PF12698.2 EGC39932.1 - 0.079 11.9 0.4 0.088 11.8 0.3 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein V_ATPase_I PF01496.14 EGC39932.1 - 0.14 10.0 2.4 0.15 9.9 1.6 1.1 1 0 0 1 1 1 0 V-type ATPase 116kDa subunit family Med11 PF10280.4 EGC39932.1 - 0.19 11.7 2.8 0.26 11.3 2.0 1.2 1 0 0 1 1 1 0 Mediator complex protein TBCA PF02970.11 EGC39932.1 - 0.39 10.8 4.2 0.18 11.8 1.3 1.6 1 1 1 2 2 2 0 Tubulin binding cofactor A DUF1461 PF07314.6 EGC39932.1 - 0.77 9.4 3.1 3.3 7.4 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF1461) Dicty_REP PF05086.7 EGC39934.1 - 2.8e-33 114.7 9.8 3.2e-33 114.5 6.8 1.0 1 0 0 1 1 1 1 Dictyostelium (Slime Mold) REP protein FTH PF01827.22 EGC39934.1 - 0.027 14.0 1.2 0.053 13.1 0.8 1.5 1 0 0 1 1 1 0 FTH domain Chromo PF00385.19 EGC39936.1 - 5.5e-15 54.7 1.5 6.1e-15 54.6 1.0 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC39936.1 - 0.1 12.2 0.1 0.12 12.0 0.1 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain Cpn60_TCP1 PF00118.19 EGC39939.1 - 3.5e-141 471.1 15.3 4e-141 470.9 10.6 1.0 1 0 0 1 1 1 1 TCP-1/cpn60 chaperonin family Nefa_Nip30_N PF10187.4 EGC39940.1 - 6.6e-16 58.3 17.0 6.6e-16 58.3 11.8 2.7 2 1 0 2 2 2 1 N-terminal domain of NEFA-interacting nuclear protein NIP30 Gal-3-0_sulfotr PF06990.6 EGC39940.1 - 0.097 11.3 0.2 0.14 10.8 0.1 1.2 1 0 0 1 1 1 0 Galactose-3-O-sulfotransferase Rad17 PF03215.10 EGC39941.1 - 9.2e-48 163.1 10.3 9.2e-48 163.1 7.1 2.3 2 0 0 2 2 2 1 Rad17 cell cycle checkpoint protein DUF258 PF03193.11 EGC39941.1 - 9.6e-05 21.6 0.1 0.00059 19.0 0.0 2.2 2 0 0 2 2 2 1 Protein of unknown function, DUF258 AAA PF00004.24 EGC39941.1 - 0.00028 21.1 0.0 0.0009 19.4 0.0 1.9 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_17 PF13207.1 EGC39941.1 - 0.00035 21.3 0.0 0.0014 19.4 0.0 2.2 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC39941.1 - 0.00046 20.3 0.9 0.01 15.9 0.1 3.2 2 1 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC39941.1 - 0.00047 20.1 0.0 0.0016 18.4 0.0 1.9 1 0 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EGC39941.1 - 0.00058 20.1 0.0 0.00058 20.1 0.0 4.0 5 0 0 5 5 5 1 AAA domain AAA_14 PF13173.1 EGC39941.1 - 0.00081 19.2 1.8 0.014 15.3 0.0 3.5 3 1 0 3 3 3 1 AAA domain Arch_ATPase PF01637.13 EGC39941.1 - 0.0021 17.7 3.0 0.0049 16.5 0.0 3.0 2 1 1 3 3 3 1 Archaeal ATPase ABC_tran PF00005.22 EGC39941.1 - 0.0024 18.1 1.8 0.0081 16.4 0.0 2.9 2 0 0 2 2 2 1 ABC transporter AAA_29 PF13555.1 EGC39941.1 - 0.0046 16.4 0.1 0.013 14.9 0.0 1.7 1 0 0 1 1 1 1 P-loop containing region of AAA domain AAA_5 PF07728.9 EGC39941.1 - 0.016 14.9 0.0 0.039 13.6 0.0 1.7 1 0 0 1 1 1 0 AAA domain (dynein-related subfamily) AAA_33 PF13671.1 EGC39941.1 - 0.023 14.5 0.0 0.073 12.9 0.0 1.9 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGC39941.1 - 0.038 13.7 0.1 0.084 12.5 0.1 1.6 1 0 0 1 1 1 0 NTPase zf-CCHH PF10283.4 EGC39941.1 - 3.2 7.6 6.9 0.11 12.3 0.4 1.9 2 0 0 2 2 2 0 Zinc-finger (CX5CX6HX5H) motif zf-DNL PF05180.7 EGC39943.1 - 4.9e-28 96.6 0.5 9.2e-28 95.7 0.4 1.5 1 0 0 1 1 1 1 DNL zinc finger Ras PF00071.17 EGC39944.1 - 9.9e-44 148.5 0.0 1.2e-43 148.3 0.0 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC39944.1 - 1.1e-13 51.7 0.0 2.1e-13 50.8 0.0 1.5 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC39944.1 - 0.0003 20.0 0.0 0.0006 19.0 0.0 1.5 1 1 0 1 1 1 1 ADP-ribosylation factor family RNA_pol_Rpb2_2 PF04561.9 EGC39944.1 - 0.023 14.0 0.0 0.053 12.9 0.0 1.5 1 1 1 2 2 2 0 RNA polymerase Rpb2, domain 2 GTP_EFTU PF00009.22 EGC39944.1 - 0.026 13.9 0.1 0.29 10.5 0.1 2.3 1 1 0 1 1 1 0 Elongation factor Tu GTP binding domain AAA_24 PF13479.1 EGC39944.1 - 0.21 11.1 2.2 0.3 10.6 0.1 2.0 2 1 0 2 2 2 0 AAA domain TPR_17 PF13431.1 EGC39945.1 - 5e-06 26.2 0.3 8.7e-05 22.4 0.1 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat Peptidase_M56 PF05569.6 EGC39946.1 - 0.11 11.4 0.8 0.24 10.3 0.5 1.5 1 0 0 1 1 1 0 BlaR1 peptidase M56 TFIIA PF03153.8 EGC39946.1 - 0.37 10.6 19.2 0.56 10.0 13.3 1.3 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit EVI2A PF05399.6 EGC39946.1 - 0.41 9.8 4.7 0.68 9.1 3.2 1.3 1 0 0 1 1 1 0 Ectropic viral integration site 2A protein (EVI2A) OTU PF02338.14 EGC39948.1 - 1.5e-12 48.1 0.0 2.7e-12 47.3 0.0 1.4 1 0 0 1 1 1 1 OTU-like cysteine protease PRA1 PF03208.14 EGC39949.1 - 0.024 13.9 4.6 0.12 11.6 3.2 1.8 1 1 0 1 1 1 0 PRA1 family protein Chromo PF00385.19 EGC39950.1 - 2.2e-15 56.0 0.7 2.4e-15 55.9 0.5 1.0 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Tudor-knot PF11717.3 EGC39950.1 - 0.096 12.4 0.1 0.12 12.1 0.0 1.2 1 0 0 1 1 1 0 RNA binding activity-knot of a chromodomain SGT1 PF07093.6 EGC39952.1 - 2e-122 409.5 50.8 2e-122 409.5 35.2 1.6 1 1 0 1 1 1 1 SGT1 protein PHP PF02811.14 EGC39952.1 - 0.047 13.4 4.5 0.051 13.3 0.5 2.5 2 0 0 2 2 2 0 PHP domain Ribosomal_L38e PF01781.13 EGC39953.1 - 1.4e-29 101.6 2.6 1.6e-29 101.4 1.8 1.0 1 0 0 1 1 1 1 Ribosomal L38e protein family ERG4_ERG24 PF01222.12 EGC39954.1 - 8.5e-76 255.2 15.0 1e-75 254.9 10.4 1.0 1 0 0 1 1 1 1 Ergosterol biosynthesis ERG4/ERG24 family DUF1295 PF06966.7 EGC39954.1 - 2.9e-07 30.0 2.1 5e-07 29.2 1.5 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1295) GATA PF00320.22 EGC39955.1 - 4.6e-16 57.8 3.7 1.1e-15 56.6 2.6 1.7 1 0 0 1 1 1 1 GATA zinc finger zf-RING_3 PF14369.1 EGC39955.1 - 0.097 12.6 0.4 0.22 11.5 0.3 1.5 1 0 0 1 1 1 0 zinc-finger Secretin_N_2 PF07655.8 EGC39956.1 - 3.4 8.1 12.4 6.1 7.3 8.6 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain NMD3 PF04981.8 EGC39957.1 - 2.4e-77 259.2 5.0 3.3e-77 258.7 3.5 1.2 1 0 0 1 1 1 1 NMD3 family zf-3CxxC PF13695.1 EGC39957.1 - 0.17 12.0 4.5 0.38 11.0 0.8 2.5 1 1 1 2 2 2 0 Zinc-binding domain DUF2360 PF10152.4 EGC39959.1 - 2.2e-11 44.2 3.2 2.2e-11 44.2 2.3 2.3 2 0 0 2 2 2 2 Predicted coiled-coil domain-containing protein (DUF2360) Nop14 PF04147.7 EGC39959.1 - 0.97 7.2 13.8 1.7 6.4 9.6 1.4 1 0 0 1 1 1 0 Nop14-like family Fer2 PF00111.22 EGC39960.1 - 9.2e-12 44.5 1.5 1.2e-11 44.2 1.1 1.1 1 0 0 1 1 1 1 2Fe-2S iron-sulfur cluster binding domain NifU PF01106.12 EGC39960.1 - 0.066 12.9 0.1 0.12 12.1 0.1 1.4 1 0 0 1 1 1 0 NifU-like domain zf-C3HC4_3 PF13920.1 EGC39961.1 - 6.2e-09 35.3 6.0 9.8e-09 34.7 4.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC39961.1 - 1.1e-07 31.5 7.0 1.7e-07 30.9 4.9 1.3 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC39961.1 - 9.7e-06 25.2 7.7 1.7e-05 24.4 5.3 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC39961.1 - 2.5e-05 24.2 9.6 4.1e-05 23.5 6.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39961.1 - 5.4e-05 22.7 8.3 0.00012 21.6 5.8 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) Cwf_Cwc_15 PF04889.7 EGC39961.1 - 0.0022 17.7 4.7 0.0032 17.2 3.2 1.2 1 0 0 1 1 1 1 Cwf15/Cwc15 cell cycle control protein zf-Di19 PF05605.7 EGC39961.1 - 0.0052 16.8 0.9 0.23 11.6 0.0 2.4 2 0 0 2 2 2 1 Drought induced 19 protein (Di19), zinc-binding zf-C3HC4_4 PF15227.1 EGC39961.1 - 0.015 15.1 7.8 0.36 10.7 5.2 2.7 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC39961.1 - 0.016 15.3 8.4 0.06 13.4 5.8 2.0 1 1 0 1 1 1 0 RING-H2 zinc finger zf-RING_UBOX PF13445.1 EGC39961.1 - 0.062 13.0 3.4 0.34 10.6 2.4 2.4 1 1 0 1 1 1 0 RING-type zinc-finger Lin-8 PF03353.10 EGC39961.1 - 0.065 12.5 6.1 0.086 12.1 4.2 1.1 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Prok-RING_4 PF14447.1 EGC39961.1 - 0.1 12.1 3.1 0.26 10.8 2.1 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-LITAF-like PF10601.4 EGC39961.1 - 0.14 12.0 4.6 22 4.9 0.0 2.6 2 1 0 2 2 2 0 LITAF-like zinc ribbon domain DUF1049 PF06305.6 EGC39961.1 - 0.19 11.1 0.0 0.19 11.1 0.0 2.3 3 0 0 3 3 2 0 Protein of unknown function (DUF1049) DUF4428 PF14471.1 EGC39961.1 - 1.3 8.8 8.6 8.3 6.2 0.1 2.4 1 1 1 2 2 2 0 Domain of unknown function (DUF4428) zf-RING_4 PF14570.1 EGC39961.1 - 1.8 8.2 11.7 12 5.5 8.2 2.1 1 1 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EGC39962.1 - 4.6e-11 42.3 9.6 7.8e-11 41.6 6.6 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39962.1 - 1.3e-08 34.3 7.5 2e-08 33.7 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39962.1 - 3e-07 29.9 12.1 5.8e-07 29.0 8.4 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC39962.1 - 4.8e-07 29.7 8.2 1.1e-06 28.5 5.7 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC39962.1 - 2.9e-06 27.1 10.5 4.8e-06 26.4 7.3 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39962.1 - 2.3e-05 24.0 9.7 4e-05 23.2 6.8 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC39962.1 - 0.002 17.6 10.6 0.0036 16.8 7.3 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain Prok-RING_4 PF14447.1 EGC39962.1 - 0.015 14.7 4.9 0.037 13.5 3.4 1.7 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 IBR PF01485.16 EGC39962.1 - 0.018 14.8 11.3 0.048 13.5 7.8 1.7 1 0 0 1 1 1 0 IBR domain zf-C3HC4_4 PF15227.1 EGC39962.1 - 0.02 14.7 10.5 0.039 13.8 6.4 2.1 1 1 1 2 2 2 0 zinc finger of C3HC4-type, RING zf-Apc11 PF12861.2 EGC39962.1 - 0.065 13.0 4.5 0.14 11.9 3.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC39962.1 - 0.079 12.6 4.2 0.37 10.5 2.9 2.3 1 0 0 1 1 1 0 RING-type zinc-finger zf-MIZ PF02891.15 EGC39962.1 - 0.23 11.0 8.0 0.61 9.6 5.6 1.7 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger DUF1272 PF06906.6 EGC39962.1 - 0.28 11.0 7.4 0.56 10.1 5.1 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_2 PF13639.1 EGC39963.1 - 1.8e-11 43.6 7.1 3.1e-11 42.9 4.9 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39963.1 - 1.1e-10 41.0 8.7 1.8e-10 40.2 6.0 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39963.1 - 1.4e-08 34.2 12.0 2.8e-08 33.2 8.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39963.1 - 2.2e-08 33.9 10.9 4.3e-08 33.0 7.5 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39963.1 - 4.2e-08 32.7 10.1 7.9e-08 31.9 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC39963.1 - 2.3e-05 24.4 4.7 5.9e-05 23.0 3.3 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC39963.1 - 0.00012 21.8 10.3 0.00032 20.4 7.2 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC39963.1 - 0.00096 18.6 8.8 0.0021 17.5 6.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC39963.1 - 0.006 16.3 3.6 0.021 14.6 2.5 1.9 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger CAF-1_p150 PF11600.3 EGC39963.1 - 0.011 15.0 46.0 0.057 12.7 26.6 2.2 2 0 0 2 2 2 0 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_UBOX PF13445.1 EGC39963.1 - 0.038 13.7 7.7 0.13 11.9 5.3 2.0 1 0 0 1 1 1 0 RING-type zinc-finger zf-RING_6 PF14835.1 EGC39963.1 - 0.053 13.3 4.6 0.11 12.2 3.2 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein N6_N4_Mtase PF01555.13 EGC39963.1 - 1.5 8.2 8.8 0.15 11.5 0.8 2.4 2 1 0 2 2 2 0 DNA methylase BK_channel_a PF03493.13 EGC39966.1 - 1.1e-25 89.4 0.0 4.4e-25 87.5 0.0 2.1 1 0 0 1 1 1 1 Calcium-activated BK potassium channel alpha subunit Ion_trans PF00520.26 EGC39966.1 - 1e-12 47.7 20.3 1e-12 47.7 14.1 2.7 2 1 0 2 2 2 1 Ion transport protein Ion_trans_2 PF07885.11 EGC39966.1 - 1.2e-10 40.9 4.5 1.2e-10 40.9 3.1 2.5 3 0 0 3 3 3 1 Ion channel DUF2951 PF11166.3 EGC39966.1 - 0.021 14.6 1.2 0.058 13.2 0.8 1.7 1 0 0 1 1 1 0 Protein of unknown function (DUF2951) TFIIF_alpha PF05793.7 EGC39966.1 - 0.43 8.8 7.5 0.75 8.0 5.2 1.3 1 0 0 1 1 1 0 Transcription initiation factor IIF, alpha subunit (TFIIF-alpha) Pkinase PF00069.20 EGC39967.1 - 1.8e-77 259.9 0.0 2.4e-77 259.6 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39967.1 - 8.9e-43 146.2 0.0 1.1e-42 145.8 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Kdo PF06293.9 EGC39967.1 - 9.7e-06 24.7 0.0 1.7e-05 24.0 0.0 1.3 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family Kinase-like PF14531.1 EGC39967.1 - 0.00048 19.1 0.1 0.0057 15.6 0.0 2.1 1 1 1 2 2 2 1 Kinase-like YrbL-PhoP_reg PF10707.4 EGC39967.1 - 0.029 13.7 0.6 0.13 11.5 0.4 2.0 1 1 0 1 1 1 0 PhoP regulatory network protein YrbL DUF3685 PF12452.3 EGC39967.1 - 0.076 12.1 0.1 0.46 9.6 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF3685) UAA PF08449.6 EGC39968.1 - 1e-93 313.6 30.4 1.2e-93 313.3 21.1 1.0 1 0 0 1 1 1 1 UAA transporter family TPT PF03151.11 EGC39968.1 - 4.4e-09 36.1 10.2 4.4e-09 36.1 7.0 2.9 2 2 0 2 2 2 1 Triose-phosphate Transporter family EamA PF00892.15 EGC39968.1 - 1.2e-05 25.3 36.3 0.00011 22.2 8.9 2.8 2 1 0 2 2 2 2 EamA-like transporter family Nuc_sug_transp PF04142.10 EGC39968.1 - 0.24 10.4 13.7 0.039 13.0 6.2 2.2 1 1 1 2 2 2 0 Nucleotide-sugar transporter tRNA-synt_2 PF00152.15 EGC39969.1 - 8.3e-76 254.9 0.0 8.3e-76 254.9 0.0 1.9 2 1 0 2 2 2 1 tRNA synthetases class II (D, K and N) tRNA_synt_1c_R1 PF04558.10 EGC39969.1 - 4.1e-42 143.4 1.8 9.5e-42 142.3 1.3 1.7 1 0 0 1 1 1 1 Glutaminyl-tRNA synthetase, non-specific RNA binding region part 1 tRNA_anti-codon PF01336.20 EGC39969.1 - 7e-12 45.0 0.0 3e-11 43.0 0.0 2.0 2 0 0 2 2 2 1 OB-fold nucleic acid binding domain tRNA-synt_2d PF01409.15 EGC39969.1 - 0.031 13.4 0.1 5.4 6.1 0.0 2.4 2 0 0 2 2 2 0 tRNA synthetases class II core domain (F) COPIIcoated_ERV PF07970.7 EGC39970.1 - 1.1e-75 254.0 0.9 4.1e-75 252.2 0.1 2.1 2 0 0 2 2 2 1 Endoplasmic reticulum vesicle transporter ERGIC_N PF13850.1 EGC39970.1 - 1.7e-35 120.8 1.6 2e-35 120.6 0.2 1.7 2 0 0 2 2 2 1 Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) PHB_depo_C PF06850.6 EGC39970.1 - 0.0086 15.3 0.0 0.014 14.6 0.0 1.3 1 0 0 1 1 1 1 PHB de-polymerase C-terminus DUF3039 PF11238.3 EGC39970.1 - 0.15 11.5 0.9 0.35 10.3 0.6 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF3039) Kelch_6 PF13964.1 EGC39971.1 - 2.5e-19 68.5 6.0 1.4e-05 25.0 0.0 6.5 4 1 2 6 6 6 4 Kelch motif Kelch_1 PF01344.20 EGC39971.1 - 9.3e-17 60.3 5.3 1.5e-05 24.4 0.0 4.6 4 0 0 4 4 4 3 Kelch motif Kelch_4 PF13418.1 EGC39971.1 - 2.4e-13 49.6 0.0 3.5e-06 26.6 0.0 4.9 5 0 0 5 5 5 2 Galactose oxidase, central domain Kelch_3 PF13415.1 EGC39971.1 - 6.6e-11 42.0 0.0 0.094 12.9 0.0 5.2 5 0 0 5 5 4 3 Galactose oxidase, central domain zf-B_box PF00643.19 EGC39971.1 - 2.7e-07 30.3 10.6 2.7e-07 30.3 7.3 3.2 3 1 0 3 3 2 1 B-box zinc finger Kelch_2 PF07646.10 EGC39971.1 - 3.7e-06 26.4 2.3 0.093 12.5 0.1 4.1 4 0 0 4 4 3 2 Kelch motif zf-C3HC4_4 PF15227.1 EGC39971.1 - 1.8e-05 24.5 11.7 1.8e-05 24.5 8.1 3.0 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-C3HC4 PF00097.20 EGC39971.1 - 0.0001 21.8 12.0 0.0001 21.8 8.4 2.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC39971.1 - 0.00042 20.0 7.8 0.00042 20.0 5.4 2.4 2 0 0 2 2 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC39971.1 - 0.00048 19.7 8.8 0.00048 19.7 6.1 2.6 2 0 0 2 2 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC39971.1 - 0.00065 19.6 12.1 0.00065 19.6 8.4 2.7 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC39971.1 - 0.0018 17.9 7.1 0.0081 15.8 4.9 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGC39971.1 - 0.002 17.8 4.9 0.002 17.8 3.4 1.9 2 0 0 2 2 1 1 zf-RING of BARD1-type protein Kelch_5 PF13854.1 EGC39971.1 - 0.0089 15.9 2.2 0.02 14.8 0.0 2.8 4 0 0 4 4 3 1 Kelch motif Glyco_hydro_9 PF00759.14 EGC39972.1 - 3.1e-146 487.7 7.8 3.5e-146 487.5 5.4 1.0 1 0 0 1 1 1 1 Glycosyl hydrolase family 9 Secretin_N_2 PF07655.8 EGC39973.1 - 0.038 14.3 8.7 0.081 13.3 6.0 1.5 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC39973.1 - 0.055 13.5 7.8 0.073 13.1 0.7 2.4 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Tetraspannin PF00335.15 EGC39973.1 - 2.5 7.3 9.1 2.1 7.5 4.8 1.9 2 0 0 2 2 2 0 Tetraspanin family Pkinase PF00069.20 EGC39974.1 - 3.3e-69 232.9 0.0 4.8e-69 232.3 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC39974.1 - 1e-48 165.6 0.0 1.6e-48 165.0 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGC39974.1 - 1e-14 54.6 0.2 3e-14 53.1 0.1 1.8 1 0 0 1 1 1 1 P21-Rho-binding domain PH PF00169.24 EGC39974.1 - 5.1e-14 52.3 0.1 1e-13 51.3 0.1 1.5 1 0 0 1 1 1 1 PH domain Kinase-like PF14531.1 EGC39974.1 - 5.6e-05 22.2 0.0 0.00022 20.2 0.0 1.8 2 0 0 2 2 2 1 Kinase-like PH_11 PF15413.1 EGC39974.1 - 0.00073 19.7 1.2 0.13 12.5 0.8 2.8 1 1 0 1 1 1 1 Pleckstrin homology domain APH PF01636.18 EGC39974.1 - 0.048 13.3 0.0 0.16 11.6 0.0 1.8 2 1 1 3 3 3 0 Phosphotransferase enzyme family ABC_tran PF00005.22 EGC39977.1 - 2.9e-44 150.6 0.7 1.1e-21 77.6 0.0 3.3 3 1 0 3 3 3 2 ABC transporter ABC_tran_2 PF12848.2 EGC39977.1 - 4.6e-20 71.2 13.7 4.6e-20 71.2 9.5 3.6 3 0 0 3 3 3 1 ABC transporter AAA_21 PF13304.1 EGC39977.1 - 1.4e-13 51.4 9.5 0.0015 18.5 2.5 5.0 4 1 0 4 4 4 3 AAA domain AAA_22 PF13401.1 EGC39977.1 - 2.8e-08 33.9 0.0 0.0035 17.4 0.0 2.9 2 1 0 2 2 2 2 AAA domain DUF258 PF03193.11 EGC39977.1 - 1.4e-06 27.6 0.1 0.047 12.8 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function, DUF258 SMC_N PF02463.14 EGC39977.1 - 1.5e-06 27.6 7.7 0.0095 15.1 0.0 4.3 3 2 1 4 4 4 2 RecF/RecN/SMC N terminal domain AAA_29 PF13555.1 EGC39977.1 - 7.1e-06 25.4 0.4 0.032 13.7 0.0 2.5 2 0 0 2 2 2 2 P-loop containing region of AAA domain AAA_10 PF12846.2 EGC39977.1 - 2.4e-05 23.9 0.6 0.18 11.2 0.0 3.1 2 1 1 3 3 3 2 AAA-like domain AAA_17 PF13207.1 EGC39977.1 - 2.6e-05 25.0 3.3 0.15 12.8 0.0 4.1 5 0 0 5 5 4 2 AAA domain MMR_HSR1 PF01926.18 EGC39977.1 - 4e-05 23.5 0.1 0.34 10.8 0.1 3.1 2 1 0 2 2 2 2 50S ribosome-binding GTPase NB-ARC PF00931.17 EGC39977.1 - 9.8e-05 21.3 0.0 0.089 11.6 0.0 2.4 2 0 0 2 2 2 2 NB-ARC domain MobB PF03205.9 EGC39977.1 - 0.0001 22.0 0.1 0.67 9.6 0.0 3.0 2 0 0 2 2 2 2 Molybdopterin guanine dinucleotide synthesis protein B NACHT PF05729.7 EGC39977.1 - 0.00018 21.1 0.4 0.24 11.0 0.0 3.0 3 0 0 3 3 3 1 NACHT domain RNA_helicase PF00910.17 EGC39977.1 - 0.0004 20.5 0.0 1.3 9.1 0.0 2.7 2 0 0 2 2 2 2 RNA helicase AAA_33 PF13671.1 EGC39977.1 - 0.001 18.9 0.1 1.6 8.5 0.0 3.0 3 0 0 3 3 3 1 AAA domain Miro PF08477.8 EGC39977.1 - 0.0018 18.7 1.2 1.3 9.5 0.0 3.0 3 0 0 3 3 2 1 Miro-like protein AAA_14 PF13173.1 EGC39977.1 - 0.003 17.4 0.1 4.2 7.2 0.0 3.2 4 0 0 4 4 3 1 AAA domain AAA_18 PF13238.1 EGC39977.1 - 0.006 16.8 1.3 1.7 8.9 0.0 3.7 3 1 0 3 3 3 1 AAA domain NTPase_1 PF03266.10 EGC39977.1 - 0.0077 15.9 0.0 1.5 8.4 0.0 2.7 2 0 0 2 2 2 1 NTPase SRP54 PF00448.17 EGC39977.1 - 0.0094 15.4 0.0 5.4 6.4 0.0 2.6 2 0 0 2 2 2 1 SRP54-type protein, GTPase domain AAA_16 PF13191.1 EGC39977.1 - 0.011 15.7 0.0 5.5 6.9 0.0 2.8 3 0 0 3 3 2 0 AAA ATPase domain AAA_25 PF13481.1 EGC39977.1 - 0.012 15.0 0.0 0.93 8.8 0.0 2.7 2 0 0 2 2 2 0 AAA domain AAA_28 PF13521.1 EGC39977.1 - 0.014 15.3 0.2 4.7 7.1 0.0 2.9 3 0 0 3 3 2 0 AAA domain SbcCD_C PF13558.1 EGC39977.1 - 0.063 13.1 0.1 1.2 9.1 0.0 2.9 2 1 0 2 2 2 0 Putative exonuclease SbcCD, C subunit ArgK PF03308.11 EGC39977.1 - 0.081 11.6 3.1 2.3 6.9 0.0 2.7 3 0 0 3 3 3 0 ArgK protein AAA PF00004.24 EGC39977.1 - 0.084 13.0 3.5 8.7 6.5 0.0 3.5 3 1 0 3 3 3 0 ATPase family associated with various cellular activities (AAA) Arf PF00025.16 EGC39977.1 - 1.5 8.0 5.6 8.4 5.6 0.0 3.0 3 0 0 3 3 3 0 ADP-ribosylation factor family PAP2 PF01569.16 EGC39978.1 - 6.7e-10 38.7 4.7 6.7e-10 38.7 3.3 2.1 2 0 0 2 2 2 1 PAP2 superfamily Peptidase_C15 PF01470.12 EGC39979.1 - 2.5e-15 56.8 0.0 3.9e-15 56.2 0.0 1.2 1 0 0 1 1 1 1 Pyroglutamyl peptidase PRESAN PF09687.5 EGC39979.1 - 0.01 15.9 2.4 0.01 15.9 1.6 2.0 1 1 1 2 2 2 0 Plasmodium RESA N-terminal Epimerase PF01370.16 EGC39981.1 - 3.5e-67 226.2 0.0 4.5e-67 225.9 0.0 1.1 1 0 0 1 1 1 1 NAD dependent epimerase/dehydratase family RmlD_sub_bind PF04321.12 EGC39981.1 - 4e-05 22.6 0.0 7.2e-05 21.8 0.0 1.3 1 0 0 1 1 1 1 RmlD substrate binding domain Epimerase_Csub PF13950.1 EGC39981.1 - 0.022 14.7 0.0 0.047 13.6 0.0 1.5 1 0 0 1 1 1 0 UDP-glucose 4-epimerase C-term subunit Polysacc_synt_2 PF02719.10 EGC39981.1 - 0.035 13.0 0.0 0.057 12.3 0.0 1.3 1 0 0 1 1 1 0 Polysaccharide biosynthesis protein Peptidase_M41 PF01434.13 EGC39982.1 - 2.5e-67 226.4 5.2 2.5e-67 226.4 3.6 3.0 2 1 1 3 3 1 1 Peptidase family M41 AAA PF00004.24 EGC39982.1 - 1.2e-42 145.1 0.0 1.2e-42 145.1 0.0 3.6 2 1 1 3 3 2 1 ATPase family associated with various cellular activities (AAA) AAA_5 PF07728.9 EGC39982.1 - 1.2e-05 25.0 0.0 1.2e-05 25.0 0.0 3.5 3 2 1 4 4 2 1 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGC39982.1 - 1.3e-05 25.9 0.4 0.00068 20.4 0.0 2.8 3 0 0 3 3 2 1 AAA domain AAA_25 PF13481.1 EGC39982.1 - 2.3e-05 23.8 0.2 0.0028 17.0 0.1 2.7 1 1 1 2 2 2 1 AAA domain AAA_14 PF13173.1 EGC39982.1 - 0.0005 19.9 0.0 0.0005 19.9 0.0 3.0 4 0 0 4 4 3 1 AAA domain AAA_16 PF13191.1 EGC39982.1 - 0.00069 19.6 0.0 0.00069 19.6 0.0 3.5 2 2 1 3 3 2 1 AAA ATPase domain AAA_33 PF13671.1 EGC39982.1 - 0.0017 18.2 0.0 0.0017 18.2 0.0 3.7 2 1 1 3 3 1 1 AAA domain RuvB_N PF05496.7 EGC39982.1 - 0.002 17.2 0.0 0.002 17.2 0.0 2.5 2 0 0 2 2 1 1 Holliday junction DNA helicase ruvB N-terminus IstB_IS21 PF01695.12 EGC39982.1 - 0.0024 17.3 0.2 0.0024 17.3 0.1 2.7 2 0 0 2 2 1 1 IstB-like ATP binding protein AAA_22 PF13401.1 EGC39982.1 - 0.003 17.6 0.0 0.003 17.6 0.0 4.0 2 2 0 2 2 1 1 AAA domain PAT1 PF09770.4 EGC39982.1 - 0.0054 15.0 54.8 0.0069 14.6 38.0 1.1 1 0 0 1 1 1 1 Topoisomerase II-associated protein PAT1 AAA_19 PF13245.1 EGC39982.1 - 0.0071 16.0 0.3 0.025 14.3 0.2 1.9 1 0 0 1 1 1 1 Part of AAA domain AAA_18 PF13238.1 EGC39982.1 - 0.013 15.8 0.0 0.013 15.8 0.0 4.1 2 1 1 3 3 2 0 AAA domain Mg_chelatase PF01078.16 EGC39982.1 - 0.013 14.6 0.2 0.013 14.6 0.1 2.9 2 1 1 4 4 4 0 Magnesium chelatase, subunit ChlI AAA_24 PF13479.1 EGC39982.1 - 0.041 13.4 0.0 0.041 13.4 0.0 3.1 3 1 0 3 3 2 0 AAA domain AAA_28 PF13521.1 EGC39982.1 - 0.052 13.5 0.0 0.052 13.5 0.0 3.5 2 1 0 2 2 1 0 AAA domain LIM PF00412.17 EGC39983.1 - 4.8e-44 148.2 109.8 2.5e-11 43.4 1.2 9.9 7 2 2 9 9 9 7 LIM domain CH PF00307.26 EGC39983.1 - 2.9e-13 49.8 0.6 1.6e-12 47.4 0.0 2.5 2 0 0 2 2 2 1 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC39983.1 - 0.00082 18.9 0.0 0.003 17.1 0.0 2.0 1 0 0 1 1 1 1 CAMSAP CH domain CDC24 PF06395.6 EGC39983.1 - 0.0045 17.0 0.1 0.011 15.8 0.1 1.6 1 0 0 1 1 1 1 CDC24 Calponin zf-RING_2 PF13639.1 EGC39985.1 - 7.3e-11 41.7 8.2 1.2e-10 41.0 5.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39985.1 - 3.5e-09 36.1 9.5 5.6e-09 35.5 6.6 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39985.1 - 6.3e-08 32.2 11.1 1.1e-07 31.4 7.7 1.4 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_2 PF13923.1 EGC39985.1 - 1.1e-07 31.7 11.7 1.8e-07 31.0 8.1 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39985.1 - 1.8e-07 30.7 13.1 3.2e-07 29.8 9.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC39985.1 - 3.9e-05 23.4 7.8 8.8e-05 22.2 5.3 1.7 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-rbx1 PF12678.2 EGC39985.1 - 0.00011 22.2 5.5 0.00025 21.0 3.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_4 PF14570.1 EGC39985.1 - 0.0012 18.4 8.2 0.0024 17.4 5.7 1.5 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC39985.1 - 0.0078 16.0 3.9 0.017 14.9 2.7 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_UBOX PF13445.1 EGC39985.1 - 0.009 15.7 6.3 0.01 15.5 3.1 2.1 1 1 0 1 1 1 1 RING-type zinc-finger zf-RING_6 PF14835.1 EGC39985.1 - 0.022 14.5 4.1 0.047 13.4 2.8 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Baculo_RING PF05883.6 EGC39985.1 - 2 8.2 10.5 0.59 9.9 4.5 2.2 2 0 0 2 2 2 0 Baculovirus U-box/Ring-like domain DZR PF12773.2 EGC39985.1 - 9 6.2 8.8 1.3e+02 2.4 5.4 2.3 1 1 1 2 2 2 0 Double zinc ribbon Methyltransf_10 PF05971.7 EGC39986.1 - 3.3e-67 226.7 0.4 5.6e-66 222.7 0.3 2.1 1 1 0 1 1 1 1 Protein of unknown function (DUF890) MTS PF05175.9 EGC39986.1 - 8.5e-07 28.5 0.0 1.7e-05 24.2 0.0 2.3 1 1 0 1 1 1 1 Methyltransferase small domain Methyltransf_31 PF13847.1 EGC39986.1 - 6e-06 25.9 2.6 2.9e-05 23.7 0.2 2.4 2 0 0 2 2 2 1 Methyltransferase domain PrmA PF06325.8 EGC39986.1 - 1.2e-05 24.6 0.0 2.8e-05 23.3 0.0 1.6 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_26 PF13659.1 EGC39986.1 - 2.3e-05 24.4 0.0 4e-05 23.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC39986.1 - 6.8e-05 23.4 0.0 0.00015 22.3 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Met_10 PF02475.11 EGC39986.1 - 0.001 18.6 0.0 0.0018 17.9 0.0 1.5 1 0 0 1 1 1 1 Met-10+ like-protein UPF0020 PF01170.13 EGC39986.1 - 0.0053 16.3 0.0 0.013 15.0 0.0 1.6 1 1 0 1 1 1 1 Putative RNA methylase family UPF0020 SAP30_Sin3_bdg PF13867.1 EGC39986.1 - 0.031 14.1 0.1 0.069 13.0 0.1 1.6 1 0 0 1 1 1 0 Sin3 binding region of histone deacetylase complex subunit SAP30 Methyltransf_11 PF08241.7 EGC39986.1 - 0.16 12.4 0.0 0.38 11.2 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_12 PF08242.7 EGC39986.1 - 0.6 10.6 2.8 2 8.9 0.0 2.9 2 1 0 2 2 2 0 Methyltransferase domain zf-CCHC_6 PF15288.1 EGC39987.1 - 0.00055 19.5 1.0 0.0012 18.5 0.7 1.5 1 0 0 1 1 1 1 Zinc knuckle zf-CCHC PF00098.18 EGC39987.1 - 0.023 14.6 1.2 0.023 14.6 0.8 1.7 2 0 0 2 2 2 0 Zinc knuckle ketoacyl-synt PF00109.21 EGC39988.1 - 4.6e-77 258.9 0.0 7.3e-77 258.2 0.0 1.3 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC39988.1 - 1.6e-57 195.2 0.0 2.9e-57 194.4 0.0 1.4 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC39988.1 - 1.6e-39 134.4 0.0 3.9e-39 133.1 0.0 1.7 1 0 0 1 1 1 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC39988.1 - 3.6e-31 108.2 0.0 5.9e-31 107.5 0.0 1.4 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC39988.1 - 2.1e-22 79.7 0.0 3.8e-22 78.9 0.0 1.5 1 0 0 1 1 1 1 short chain dehydrogenase PS-DH PF14765.1 EGC39988.1 - 5.3e-22 78.3 0.0 8.6e-22 77.6 0.0 1.2 1 0 0 1 1 1 1 Polyketide synthase dehydratase ADH_zinc_N_2 PF13602.1 EGC39988.1 - 2.1e-09 38.3 0.0 5.5e-09 36.9 0.0 1.8 1 0 0 1 1 1 1 Zinc-binding dehydrogenase PP-binding PF00550.20 EGC39988.1 - 4e-08 33.3 0.1 2e-07 31.1 0.1 2.4 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC39988.1 - 1.3e-06 27.6 0.1 2.8e-06 26.5 0.1 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain ADH_N PF08240.7 EGC39988.1 - 1.5e-06 27.9 0.0 5.2e-06 26.1 0.0 2.0 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_12 PF08242.7 EGC39988.1 - 0.0054 17.1 0.1 0.044 14.2 0.0 2.7 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC39988.1 - 0.054 13.9 0.0 0.2 12.1 0.0 2.1 1 0 0 1 1 1 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC39988.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.8 1 0 0 1 1 1 0 Methyltransferase domain Y_Y_Y PF07495.8 EGC39989.1 - 0.24 11.1 12.9 0.2 11.4 0.1 4.9 5 0 0 5 5 5 0 Y_Y_Y domain DUF4137 PF13593.1 EGC39990.1 - 3.9e-05 22.9 1.5 7e-05 22.0 1.0 1.4 1 0 0 1 1 1 1 SBF-like CPA transporter family (DUF4137) FimP PF09766.4 EGC39991.1 - 1.4e-57 195.4 16.7 8.2e-33 113.9 7.0 2.2 1 1 1 2 2 2 2 Fms-interacting protein DUF869 PF05911.6 EGC39991.1 - 0.015 13.6 5.8 0.019 13.1 4.0 1.1 1 0 0 1 1 1 0 Plant protein of unknown function (DUF869) CBM_11 PF03425.8 EGC39991.1 - 0.022 14.4 3.6 1.9 8.1 0.3 3.3 3 0 0 3 3 3 0 Carbohydrate binding domain (family 11) Corona_S2 PF01601.11 EGC39991.1 - 1.4 6.9 5.5 0.4 8.7 1.1 1.9 1 1 1 2 2 2 0 Coronavirus S2 glycoprotein Caldesmon PF02029.10 EGC39992.1 - 0.0033 15.9 0.7 0.0033 15.9 0.5 2.1 2 0 0 2 2 2 1 Caldesmon Vma12 PF11712.3 EGC39992.1 - 0.0041 16.8 2.5 0.0041 16.8 1.7 2.2 2 0 0 2 2 2 1 Endoplasmic reticulum-based factor for assembly of V-ATPase 60KD_IMP PF02096.15 EGC39992.1 - 0.14 11.7 3.7 0.24 11.0 2.5 1.4 1 0 0 1 1 1 0 60Kd inner membrane protein Zip PF02535.17 EGC39992.1 - 0.72 8.8 3.6 4.4 6.2 0.2 2.1 2 0 0 2 2 2 0 ZIP Zinc transporter Neur_chan_memb PF02932.11 EGC39992.1 - 1.7 8.4 5.0 5.4 6.8 0.7 2.2 2 0 0 2 2 2 0 Neurotransmitter-gated ion-channel transmembrane region V-SNARE_C PF12352.3 EGC39993.1 - 3.5e-17 62.2 7.2 1.7e-16 60.0 2.2 2.6 2 1 1 3 3 3 1 Snare region anchored in the vesicle membrane C-terminus Sec20 PF03908.8 EGC39993.1 - 9.7e-09 34.8 0.6 9.7e-09 34.8 0.4 2.7 2 1 1 3 3 3 1 Sec20 E2F_TDP PF02319.15 EGC39993.1 - 0.027 14.0 1.2 0.059 12.9 0.6 1.8 1 1 0 1 1 1 0 E2F/DP family winged-helix DNA-binding domain MobC PF05713.6 EGC39993.1 - 0.055 13.4 0.0 0.2 11.6 0.0 1.9 1 0 0 1 1 1 0 Bacterial mobilisation protein (MobC) DUF1759 PF03564.10 EGC39993.1 - 0.37 10.5 6.8 2.2 8.0 1.0 2.4 1 1 0 2 2 2 0 Protein of unknown function (DUF1759) Coatomer_E PF04733.9 EGC39994.1 - 4.7e-81 272.1 4.1 5.4e-81 271.9 2.9 1.0 1 0 0 1 1 1 1 Coatomer epsilon subunit TPR_19 PF14559.1 EGC39994.1 - 2.3e-07 31.0 8.4 6e-05 23.3 0.0 4.3 3 2 1 4 4 4 1 Tetratricopeptide repeat PPR_2 PF13041.1 EGC39994.1 - 2.9e-07 30.3 4.9 0.0053 16.7 0.1 4.9 3 2 3 6 6 6 2 PPR repeat family Apc3 PF12895.2 EGC39994.1 - 1.8e-05 24.7 5.4 0.37 10.9 0.0 3.7 3 1 1 4 4 4 2 Anaphase-promoting complex, cyclosome, subunit 3 TPR_11 PF13414.1 EGC39994.1 - 4e-05 23.1 7.9 0.00019 21.0 0.0 4.0 2 2 1 4 4 4 1 TPR repeat TPR_12 PF13424.1 EGC39994.1 - 5e-05 23.1 5.0 0.023 14.5 0.0 5.3 2 2 4 6 6 6 1 Tetratricopeptide repeat PPR_3 PF13812.1 EGC39994.1 - 0.00011 22.1 0.1 1 9.8 0.0 5.2 6 0 0 6 6 6 1 Pentatricopeptide repeat domain TPR_16 PF13432.1 EGC39994.1 - 0.00013 22.5 0.9 0.61 10.8 0.0 3.7 4 0 0 4 4 3 1 Tetratricopeptide repeat TPR_14 PF13428.1 EGC39994.1 - 0.00018 21.8 0.7 3.5 8.5 0.1 4.7 4 1 1 5 5 5 1 Tetratricopeptide repeat TPR_1 PF00515.23 EGC39994.1 - 0.00057 19.3 4.3 1.9 8.2 0.0 5.3 6 0 0 6 6 6 1 Tetratricopeptide repeat PPR PF01535.15 EGC39994.1 - 0.0011 18.7 7.1 1.4 9.0 0.0 5.1 6 0 0 6 6 6 2 PPR repeat TPR_17 PF13431.1 EGC39994.1 - 0.014 15.5 1.0 49 4.4 0.0 4.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC39994.1 - 0.079 12.9 9.5 0.96 9.5 0.0 5.1 6 0 0 6 6 6 0 Tetratricopeptide repeat NARP1 PF12569.3 EGC39994.1 - 0.087 11.5 2.3 0.12 11.1 0.1 2.1 3 0 0 3 3 3 0 NMDA receptor-regulated protein 1 PI-PLC-X PF00388.14 EGC39995.1 - 6.7e-06 25.5 0.0 1.3e-05 24.6 0.0 1.5 1 0 0 1 1 1 1 Phosphatidylinositol-specific phospholipase C, X domain Varsurf_PPLC PF03490.8 EGC39995.1 - 0.00048 19.7 0.1 0.0011 18.6 0.0 1.6 1 0 0 1 1 1 1 Variant-surface-glycoprotein phospholipase C Bcr-Abl_Oligo PF09036.5 EGC39995.1 - 0.11 12.4 0.0 0.23 11.4 0.0 1.5 1 0 0 1 1 1 0 Bcr-Abl oncoprotein oligomerisation domain LMWPc PF01451.16 EGC39996.1 - 7.7e-29 100.7 0.0 1.3e-27 96.7 0.0 2.0 1 1 0 1 1 1 1 Low molecular weight phosphotyrosine protein phosphatase zf-RING_2 PF13639.1 EGC39997.1 - 2.1e-11 43.4 6.8 3.6e-11 42.6 4.7 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC39997.1 - 4.6e-10 39.0 8.8 7.6e-10 38.3 6.1 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC39997.1 - 2.2e-08 33.9 11.1 3.9e-08 33.1 7.7 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC39997.1 - 2.4e-08 33.5 12.0 4.6e-08 32.5 8.3 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC39997.1 - 1e-07 31.5 10.1 1.9e-07 30.7 7.0 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-rbx1 PF12678.2 EGC39997.1 - 3e-05 24.0 4.6 7.8e-05 22.7 3.2 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_4 PF15227.1 EGC39997.1 - 0.0001 22.0 10.1 0.00027 20.7 7.0 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC39997.1 - 0.0019 17.7 8.8 0.0042 16.6 6.1 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain CAF-1_p150 PF11600.3 EGC39997.1 - 0.0056 16.0 48.3 0.027 13.8 28.2 2.1 2 0 0 2 2 2 2 Chromatin assembly factor 1 complex p150 subunit, N-terminal zf-RING_UBOX PF13445.1 EGC39997.1 - 0.012 15.3 6.2 0.046 13.4 4.3 2.1 1 1 0 1 1 1 0 RING-type zinc-finger zf-Apc11 PF12861.2 EGC39997.1 - 0.017 14.9 3.4 0.017 14.9 2.3 1.8 2 0 0 2 2 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_6 PF14835.1 EGC39997.1 - 0.075 12.8 4.9 0.15 11.8 3.4 1.4 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Med15 PF09606.5 EGC39997.1 - 1.2 7.2 31.3 1.9 6.6 21.7 1.2 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal SH2 PF00017.19 EGC39999.1 - 6.1e-10 38.7 1.1 4.1e-09 36.1 0.0 2.8 3 0 0 3 3 3 1 SH2 domain Dict-STAT-coil PF09267.5 EGC39999.1 - 2.5e-06 27.6 2.8 2.5e-06 27.6 1.9 3.9 4 0 0 4 4 4 1 Dictyostelium STAT, coiled coil Abhydrolase_2 PF02230.11 EGC40000.1 - 3.8e-58 196.4 0.1 4.2e-58 196.3 0.1 1.0 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase Abhydrolase_5 PF12695.2 EGC40000.1 - 4.9e-10 39.3 0.0 6.7e-10 38.8 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family FSH1 PF03959.8 EGC40000.1 - 2.5e-06 27.0 0.0 6.9e-06 25.6 0.0 1.6 1 1 0 1 1 1 1 Serine hydrolase (FSH1) Abhydrolase_6 PF12697.2 EGC40000.1 - 0.00013 21.9 0.0 0.11 12.4 0.0 2.2 1 1 1 2 2 2 2 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC40000.1 - 0.0036 16.5 0.0 0.017 14.3 0.0 2.0 2 1 1 3 3 3 1 Prolyl oligopeptidase family Choline_kinase PF01633.15 EGC40001.1 - 2.1e-65 220.2 0.9 2.1e-65 220.2 0.6 1.9 2 0 0 2 2 2 1 Choline/ethanolamine kinase APH PF01636.18 EGC40001.1 - 2.4e-09 37.3 0.0 4e-09 36.5 0.0 1.4 1 1 0 1 1 1 1 Phosphotransferase enzyme family EcKinase PF02958.15 EGC40001.1 - 6.1e-05 22.3 0.3 0.00013 21.2 0.2 1.6 1 1 0 1 1 1 1 Ecdysteroid kinase Kdo PF06293.9 EGC40001.1 - 0.12 11.4 0.1 0.41 9.6 0.0 1.8 2 0 0 2 2 2 0 Lipopolysaccharide kinase (Kdo/WaaP) family EamA PF00892.15 EGC40002.1 - 1.1e-31 109.5 32.8 1.5e-18 67.0 7.3 2.2 2 0 0 2 2 2 2 EamA-like transporter family EmrE PF13536.1 EGC40002.1 - 3.9e-06 27.0 32.6 1.9e-05 24.8 3.8 3.4 3 1 1 4 4 4 3 Multidrug resistance efflux transporter IncA PF04156.9 EGC40002.1 - 0.0043 16.6 0.0 0.015 14.8 0.0 2.0 1 1 0 1 1 1 1 IncA protein Syndecan PF01034.15 EGC40002.1 - 0.013 15.1 0.1 0.013 15.1 0.1 2.7 3 0 0 3 3 3 0 Syndecan domain MgtC PF02308.11 EGC40002.1 - 0.021 14.6 0.1 0.059 13.2 0.1 1.8 1 0 0 1 1 1 0 MgtC family DUF2065 PF09838.4 EGC40002.1 - 0.027 14.1 1.2 4.3 7.1 0.3 2.6 2 0 0 2 2 2 0 Uncharacterized protein conserved in bacteria (DUF2065) Orbi_NS3 PF01616.11 EGC40002.1 - 0.054 12.4 0.4 1.5 7.7 0.0 2.4 2 0 0 2 2 2 0 Orbivirus NS3 Coa1 PF08695.5 EGC40003.1 - 0.0021 17.5 0.0 0.29 10.6 0.0 2.4 2 0 0 2 2 2 2 Cytochrome oxidase complex assembly protein 1 COLFI PF01410.13 EGC40003.1 - 0.05 13.0 0.4 0.071 12.5 0.3 1.2 1 0 0 1 1 1 0 Fibrillar collagen C-terminal domain Methyltransf_16 PF10294.4 EGC40004.1 - 6.1e-22 77.9 0.1 8.4e-22 77.4 0.0 1.1 1 0 0 1 1 1 1 Putative methyltransferase Methyltransf_23 PF13489.1 EGC40004.1 - 3.7e-08 33.2 0.0 6.2e-08 32.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC40004.1 - 1.5e-06 27.8 0.2 2.4e-06 27.1 0.1 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40004.1 - 5.2e-06 27.0 0.0 8.2e-06 26.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC40004.1 - 1.6e-05 25.2 0.2 0.00012 22.5 0.0 2.0 2 0 0 2 2 2 1 Methyltransferase domain TehB PF03848.9 EGC40004.1 - 7.1e-05 22.0 0.9 0.00011 21.4 0.1 1.7 1 1 1 2 2 2 1 Tellurite resistance protein TehB MTS PF05175.9 EGC40004.1 - 0.0022 17.3 0.0 0.0036 16.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_11 PF08241.7 EGC40004.1 - 0.0035 17.8 0.0 0.0068 16.8 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain SF3b10 PF07189.6 EGC40005.1 - 6e-36 122.1 0.0 6.8e-36 121.9 0.0 1.0 1 0 0 1 1 1 1 Splicing factor 3B subunit 10 (SF3b10) Mito_carr PF00153.22 EGC40006.1 - 4.5e-63 208.9 6.2 1.7e-21 75.7 0.3 3.0 3 0 0 3 3 3 3 Mitochondrial carrier protein RRM_1 PF00076.17 EGC40007.1 - 2.8e-24 84.5 0.6 2e-14 52.9 0.1 3.0 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC40007.1 - 5.9e-20 70.8 1.7 1.2e-09 37.8 0.0 3.3 3 0 0 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC40007.1 - 8.9e-13 48.0 0.1 8.2e-08 32.1 0.0 2.7 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Nup35_RRM_2 PF14605.1 EGC40007.1 - 0.0092 15.7 0.0 4.6 7.1 0.0 2.4 2 0 0 2 2 2 2 Nup53/35/40-type RNA recognition motif DEPP PF15343.1 EGC40008.1 - 0.0086 15.7 5.1 11 5.5 0.1 4.0 1 1 3 4 4 4 4 Decidual protein induced by progesterone family FNIP PF05725.7 EGC40009.1 - 4.2e-17 61.8 72.8 1.3e-08 34.6 0.8 12.5 10 3 2 12 12 12 8 FNIP Repeat ubiquitin PF00240.18 EGC40010.1 - 3.5e-20 71.1 0.4 6.2e-20 70.3 0.3 1.3 1 0 0 1 1 1 1 Ubiquitin family Rad60-SLD PF11976.3 EGC40010.1 - 1.9e-09 37.0 1.1 3.2e-09 36.3 0.8 1.4 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like UBA PF00627.26 EGC40010.1 - 2.3e-06 27.2 1.1 1e-05 25.2 0.0 2.8 2 0 0 2 2 2 1 UBA/TS-N domain DUF2407 PF10302.4 EGC40010.1 - 3.5e-05 23.8 0.0 7.2e-05 22.9 0.0 1.6 1 0 0 1 1 1 1 DUF2407 ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGC40010.1 - 0.0089 15.8 0.0 0.019 14.8 0.0 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC40010.1 - 0.021 15.0 0.3 0.069 13.4 0.2 1.9 1 1 0 1 1 1 0 Ubiquitin-like domain DUF1313 PF07011.6 EGC40010.1 - 0.16 11.6 3.6 5.2 6.8 0.6 2.8 2 0 0 2 2 2 0 Protein of unknown function (DUF1313) Mod_r PF07200.8 EGC40010.1 - 0.42 10.5 3.2 0.4 10.5 1.0 1.8 2 0 0 2 2 2 0 Modifier of rudimentary (Mod(r)) protein Yippee-Mis18 PF03226.9 EGC40011.1 - 1.6e-20 72.9 1.2 2.1e-20 72.5 0.9 1.1 1 0 0 1 1 1 1 Yippee zinc-binding/DNA-binding /Mis18, centromere assembly RIG-I_C-RD PF11648.3 EGC40011.1 - 0.19 11.6 2.3 0.44 10.4 1.6 1.6 1 1 0 1 1 1 0 C-terminal domain of RIG-I CDKN3 PF05706.7 EGC40012.1 - 1.7e-06 27.6 0.0 3e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 Cyclin-dependent kinase inhibitor 3 (CDKN3) Y_phosphatase3 PF13350.1 EGC40012.1 - 1.4e-05 25.4 0.3 3.8e-05 24.0 0.0 2.0 2 1 0 2 2 2 1 Tyrosine phosphatase family DSPc PF00782.15 EGC40012.1 - 0.00014 21.4 0.0 0.00029 20.4 0.0 1.5 1 1 0 1 1 1 1 Dual specificity phosphatase, catalytic domain Y_phosphatase2 PF03162.8 EGC40012.1 - 0.00015 21.1 0.1 0.00034 20.0 0.0 1.6 2 0 0 2 2 2 1 Tyrosine phosphatase family Y_phosphatase PF00102.22 EGC40012.1 - 0.0005 19.4 0.0 0.00098 18.5 0.0 1.5 1 1 0 1 1 1 1 Protein-tyrosine phosphatase PTPlike_phytase PF14566.1 EGC40012.1 - 0.012 15.6 0.2 0.029 14.4 0.0 1.8 2 0 0 2 2 2 0 Inositol hexakisphosphate DnaJ-X PF14308.1 EGC40013.1 - 4.2e-32 111.0 2.6 4.2e-32 111.0 1.8 2.1 2 0 0 2 2 2 1 X-domain of DnaJ-containing DnaJ PF00226.26 EGC40013.1 - 1.7e-27 94.8 6.5 1.7e-27 94.8 4.5 2.2 2 0 0 2 2 2 1 DnaJ domain Armet PF10208.4 EGC40013.1 - 0.0005 19.7 3.7 0.0062 16.2 0.0 2.8 3 0 0 3 3 3 1 Degradation arginine-rich protein for mis-folding PTB PF08416.8 EGC40013.1 - 0.028 14.3 0.0 0.35 10.7 0.0 2.2 2 0 0 2 2 2 0 Phosphotyrosine-binding domain Nop16 PF09420.5 EGC40013.1 - 0.44 10.6 8.2 0.057 13.5 2.3 2.0 2 2 0 2 2 2 0 Ribosome biogenesis protein Nop16 TipAS PF07739.8 EGC40013.1 - 3.2 8.0 10.2 11 6.3 0.9 3.6 2 2 0 2 2 2 0 TipAS antibiotic-recognition domain CD36 PF01130.16 EGC40014.1 - 8.7e-45 152.8 12.1 9.8e-23 80.1 1.5 2.5 2 2 0 2 2 2 2 CD36 family DUF3185 PF11381.3 EGC40014.1 - 0.002 17.8 3.1 0.33 10.7 0.1 2.6 2 0 0 2 2 2 2 Protein of unknown function (DUF3185) YopD PF05844.7 EGC40014.1 - 0.033 13.2 0.4 0.05 12.6 0.3 1.2 1 0 0 1 1 1 0 YopD protein DUF4190 PF13828.1 EGC40014.1 - 6.7 6.3 9.3 1.3 8.6 0.5 2.3 2 0 0 2 2 2 0 Domain of unknown function (DUF4190) Acetyltransf_3 PF13302.1 EGC40015.1 - 1.1e-15 58.0 0.0 1.4e-15 57.7 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_4 PF13420.1 EGC40015.1 - 1.2e-07 31.7 0.0 1.5e-07 31.4 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_1 PF00583.19 EGC40015.1 - 9.5e-05 22.3 0.0 0.00016 21.6 0.0 1.4 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family DUF1510 PF07423.6 EGC40016.1 - 0.0029 17.0 2.9 0.0029 17.0 2.0 3.1 3 1 0 3 3 3 1 Protein of unknown function (DUF1510) Ion_trans PF00520.26 EGC40016.1 - 0.075 12.2 0.8 0.13 11.4 0.5 1.4 1 0 0 1 1 1 0 Ion transport protein Tetraspannin PF00335.15 EGC40016.1 - 0.14 11.3 22.2 2.3e+02 0.9 15.4 3.0 1 1 0 1 1 1 0 Tetraspanin family HCO3_cotransp PF00955.16 EGC40016.1 - 5.3 5.5 6.7 8.6 4.8 4.7 1.2 1 0 0 1 1 1 0 HCO3- transporter family CD36 PF01130.16 EGC40017.1 - 2.4e-46 158.0 15.7 3.3e-24 85.0 2.3 2.7 2 1 0 2 2 2 2 CD36 family DUF3439 PF11921.3 EGC40019.1 - 0.0029 17.3 1.8 0.0055 16.4 1.3 1.5 1 0 0 1 1 1 1 Domain of unknown function (DUF3439) Mucin PF01456.12 EGC40019.1 - 0.15 11.8 8.8 0.3 10.8 6.1 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein Homeobox PF00046.24 EGC40020.1 - 8.7e-17 60.4 3.4 2.1e-16 59.2 2.4 1.7 1 0 0 1 1 1 1 Homeobox domain Homeobox_KN PF05920.6 EGC40020.1 - 2.2e-06 27.2 0.0 9.8e-06 25.1 0.0 2.1 1 0 0 1 1 1 1 Homeobox KN domain Homez PF11569.3 EGC40020.1 - 0.0032 16.5 0.4 0.0065 15.5 0.3 1.5 1 0 0 1 1 1 1 Homeodomain leucine-zipper encoding, Homez ER PF01133.12 EGC40021.1 - 1.4e-45 153.2 2.6 1.5e-45 153.0 1.8 1.0 1 0 0 1 1 1 1 Enhancer of rudimentary TelA PF05816.6 EGC40021.1 - 0.019 13.6 0.1 0.024 13.3 0.1 1.1 1 0 0 1 1 1 0 Toxic anion resistance protein (TelA) Tenui_NCP PF04876.7 EGC40021.1 - 0.043 13.3 0.3 0.052 13.0 0.2 1.3 1 1 0 1 1 1 0 Tenuivirus major non-capsid protein CPG4 PF15481.1 EGC40021.1 - 0.12 12.7 0.1 0.15 12.4 0.0 1.1 1 0 0 1 1 1 0 Chondroitin proteoglycan 4 F5_F8_type_C PF00754.20 EGC40022.1 - 5.5e-21 74.7 1.3 8.2e-21 74.1 0.9 1.2 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC40022.1 - 6e-14 51.4 0.1 1.6e-13 50.1 0.1 1.7 1 0 0 1 1 1 1 H-type lectin domain DEAD PF00270.24 EGC40023.1 - 4.2e-44 150.0 0.0 8.2e-44 149.0 0.0 1.5 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC40023.1 - 2.8e-26 91.1 0.1 7.7e-26 89.7 0.1 1.8 1 0 0 1 1 1 1 Helicase conserved C-terminal domain ResIII PF04851.10 EGC40023.1 - 1.9e-08 34.3 0.1 4.6e-08 33.0 0.0 1.7 1 1 0 1 1 1 1 Type III restriction enzyme, res subunit SNF2_N PF00176.18 EGC40023.1 - 6e-06 25.2 0.0 1.1e-05 24.4 0.0 1.5 1 0 0 1 1 1 1 SNF2 family N-terminal domain Terminase_1 PF03354.10 EGC40023.1 - 0.0022 16.5 0.0 0.0046 15.4 0.0 1.5 1 0 0 1 1 1 1 Phage Terminase AAA_19 PF13245.1 EGC40023.1 - 0.0047 16.6 0.0 0.016 14.9 0.0 1.8 2 0 0 2 2 2 1 Part of AAA domain Flavi_DEAD PF07652.9 EGC40023.1 - 0.017 14.8 0.1 0.11 12.2 0.0 2.3 1 1 1 2 2 2 0 Flavivirus DEAD domain PTA_PTB PF01515.14 EGC40023.1 - 0.042 12.9 0.0 0.085 11.9 0.0 1.4 1 0 0 1 1 1 0 Phosphate acetyl/butaryl transferase AAA_22 PF13401.1 EGC40023.1 - 0.071 13.2 0.3 0.77 9.8 0.2 2.3 1 1 0 1 1 1 0 AAA domain Myosin_head PF00063.16 EGC40024.1 - 5e-211 702.4 0.0 3.6e-210 699.5 0.0 2.2 1 1 0 1 1 1 1 Myosin head (motor domain) AAA_16 PF13191.1 EGC40024.1 - 0.00094 19.2 0.0 0.0059 16.6 0.0 2.2 3 0 0 3 3 3 1 AAA ATPase domain AAA_22 PF13401.1 EGC40024.1 - 0.0029 17.7 0.0 0.017 15.2 0.0 2.1 2 0 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC40024.1 - 0.013 15.2 0.0 0.033 13.9 0.0 1.7 1 0 0 1 1 1 0 Part of AAA domain T2SE PF00437.15 EGC40024.1 - 0.067 12.0 0.0 0.2 10.5 0.0 1.7 2 0 0 2 2 2 0 Type II/IV secretion system protein ABC_tran PF00005.22 EGC40024.1 - 0.071 13.4 0.0 0.24 11.7 0.0 1.9 1 0 0 1 1 1 0 ABC transporter Sigma54_activat PF00158.21 EGC40024.1 - 0.073 12.5 0.0 0.21 11.0 0.0 1.7 1 0 0 1 1 1 0 Sigma-54 interaction domain Zeta_toxin PF06414.7 EGC40024.1 - 0.13 11.2 0.0 0.42 9.6 0.0 1.8 1 0 0 1 1 1 0 Zeta toxin Hat1_N PF10394.4 EGC40025.1 - 1e-41 142.7 3.2 1e-41 142.7 2.2 2.0 2 1 0 2 2 2 1 Histone acetyl transferase HAT1 N-terminus Acetyltransf_10 PF13673.1 EGC40025.1 - 0.00078 19.5 0.4 0.017 15.2 0.0 2.5 2 0 0 2 2 2 1 Acetyltransferase (GNAT) domain MOZ_SAS PF01853.13 EGC40025.1 - 0.0048 16.1 0.5 0.011 15.0 0.3 1.6 1 0 0 1 1 1 1 MOZ/SAS family Acetyltransf_7 PF13508.1 EGC40025.1 - 0.0049 16.9 0.0 0.012 15.7 0.0 1.6 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain GNAT_acetyltr_2 PF13718.1 EGC40025.1 - 0.0062 15.8 0.1 1.6 7.9 0.0 2.2 2 0 0 2 2 2 2 GNAT acetyltransferase 2 Acetyltransf_1 PF00583.19 EGC40025.1 - 0.13 12.3 0.0 0.27 11.2 0.0 1.5 1 0 0 1 1 1 0 Acetyltransferase (GNAT) family FNIP PF05725.7 EGC40026.1 - 2.7e-133 433.7 51.4 3.2e-16 58.9 0.0 11.2 7 3 2 11 11 11 11 FNIP Repeat Phage_min_tail PF05939.8 EGC40026.1 - 2.1e-07 30.8 0.0 34 4.4 0.0 8.8 3 3 7 11 11 11 0 Phage minor tail protein DUF3215 PF11503.3 EGC40026.1 - 0.1 12.2 0.9 5.9 6.6 0.0 4.4 6 0 0 6 6 6 0 Protein of unknown function (DUF3215) Bclx_interact PF08945.5 EGC40026.1 - 0.17 11.4 11.8 46 3.6 0.0 7.0 8 0 0 8 8 8 0 Bcl-x interacting, BH3 domain LRR_6 PF13516.1 EGC40026.1 - 1.7 8.9 38.5 66 4.0 0.0 14.3 18 1 1 19 19 19 0 Leucine Rich repeat TIM PF00121.13 EGC40028.1 - 5.7e-91 303.9 0.5 6.4e-91 303.7 0.3 1.0 1 0 0 1 1 1 1 Triosephosphate isomerase ubiquitin PF00240.18 EGC40029.1 - 2e-168 546.0 31.0 2.4e-33 113.3 0.6 5.0 5 0 0 5 5 5 5 Ubiquitin family Rad60-SLD PF11976.3 EGC40029.1 - 5.9e-95 311.0 26.9 2e-18 65.8 0.4 5.0 5 0 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like Ubiquitin_2 PF14560.1 EGC40029.1 - 5.2e-29 100.3 14.9 0.0003 20.9 0.1 6.9 5 5 0 5 5 5 5 Ubiquitin-like domain Rad60-SLD_2 PF13881.1 EGC40029.1 - 6.1e-16 58.2 4.1 0.3 10.9 0.0 5.9 5 4 0 5 5 5 5 Ubiquitin-2 like Rad60 SUMO-like DUF2407 PF10302.4 EGC40029.1 - 1.2e-15 57.4 2.1 0.42 10.8 0.0 5.2 1 1 3 5 5 5 5 DUF2407 ubiquitin-like domain DUF2870 PF11069.3 EGC40029.1 - 3.1e-13 49.6 0.0 2 8.4 0.0 5.7 5 0 0 5 5 5 5 Protein of unknown function (DUF2870) TUG-UBL1 PF11470.3 EGC40029.1 - 6.5e-08 32.3 7.7 6.3 6.7 0.0 5.2 5 0 0 5 5 5 5 GLUT4 regulating protein TUG Methyltrans_RNA PF04452.9 EGC40029.1 - 7.6e-08 31.7 2.2 2.4 7.2 0.0 4.2 4 0 0 4 4 4 4 RNA methyltransferase Big_3_3 PF13750.1 EGC40029.1 - 1.4e-07 31.1 0.1 16 4.8 0.0 5.1 5 0 0 5 5 5 0 Bacterial Ig-like domain (group 3) Corona_NS2A PF05213.7 EGC40029.1 - 1.2e-06 28.0 0.0 21 4.3 0.0 5.0 1 1 1 5 5 5 0 Coronavirus NS2A protein IGR PF09597.5 EGC40029.1 - 2e-06 27.5 0.1 45 4.0 0.0 5.3 5 0 0 5 5 5 0 IGR protein motif DUF3435 PF11917.3 EGC40029.1 - 0.00014 20.7 1.1 31 3.1 0.0 4.8 5 0 0 5 5 5 0 Protein of unknown function (DUF3435) Plexin_cytopl PF08337.7 EGC40029.1 - 0.00058 18.3 14.6 6 5.0 0.1 6.7 6 4 0 6 6 6 4 Plexin cytoplasmic RasGAP domain FlgD_ig PF13860.1 EGC40029.1 - 0.001 18.7 7.3 51 3.7 0.0 5.2 5 0 0 5 5 5 0 FlgD Ig-like domain ACT_4 PF13291.1 EGC40029.1 - 0.0013 19.0 0.2 2.1e+02 2.3 0.0 5.0 5 0 0 5 5 5 0 ACT domain DUF3642 PF12182.3 EGC40029.1 - 0.0018 18.6 10.6 52 4.3 0.0 5.4 5 0 0 5 5 5 0 Bacterial lipoprotein GABP-alpha PF11620.3 EGC40029.1 - 0.04 13.9 8.6 90 3.1 0.0 4.9 5 0 0 5 5 5 0 GA-binding protein alpha chain DUF3781 PF12636.2 EGC40029.1 - 0.18 11.7 8.5 1.5e+02 2.4 0.0 5.0 5 0 0 5 5 5 0 Protein of unknown function (DUF3781) NICE-3 PF07406.6 EGC40030.1 - 0.0037 16.7 1.3 0.0053 16.2 0.9 1.5 1 1 0 1 1 1 1 NICE-3 protein BolA PF01722.13 EGC40031.1 - 5e-14 52.0 0.0 5.2e-14 51.9 0.0 1.0 1 0 0 1 1 1 1 BolA-like protein Thiolase_N PF00108.18 EGC40032.1 - 1.2e-88 296.5 0.9 2e-88 295.8 0.6 1.3 1 0 0 1 1 1 1 Thiolase, N-terminal domain Thiolase_C PF02803.13 EGC40032.1 - 3.8e-46 155.5 2.3 7.3e-46 154.5 0.4 2.1 2 0 0 2 2 2 1 Thiolase, C-terminal domain ketoacyl-synt PF00109.21 EGC40032.1 - 0.0026 17.2 0.2 0.0026 17.2 0.2 2.0 3 0 0 3 3 3 1 Beta-ketoacyl synthase, N-terminal domain ACP_syn_III PF08545.5 EGC40032.1 - 0.015 14.9 0.6 3.9 7.1 0.0 2.6 2 0 0 2 2 2 0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III Myosin_N PF02736.14 EGC40032.1 - 0.029 14.0 1.8 0.066 12.8 1.3 1.6 1 0 0 1 1 1 0 Myosin N-terminal SH3-like domain Mcm10 PF09332.6 EGC40033.1 - 0.0038 16.6 5.7 0.0046 16.3 4.0 1.0 1 0 0 1 1 1 1 Mcm10 replication factor DUF724 PF05266.9 EGC40033.1 - 0.26 10.8 5.3 0.48 10.0 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF724) BRE1 PF08647.6 EGC40033.1 - 0.41 10.6 12.4 0.061 13.3 5.6 1.9 2 1 0 2 2 2 0 BRE1 E3 ubiquitin ligase TFIIA PF03153.8 EGC40033.1 - 0.86 9.4 13.0 1.1 9.1 9.0 1.1 1 0 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit APC_CDC26 PF10471.4 EGC40033.1 - 0.88 10.3 13.8 0.87 10.3 4.2 2.7 2 1 0 2 2 2 0 Anaphase-promoting complex APC subunit 1 Patatin PF01734.17 EGC40034.1 - 1.6e-24 86.9 0.0 5e-24 85.3 0.0 1.9 2 0 0 2 2 2 1 Patatin-like phospholipase Phospholip_B PF04916.8 EGC40035.1 - 5.9e-138 460.3 11.7 7.9e-138 459.9 8.1 1.0 1 0 0 1 1 1 1 Phospholipase B COQ9 PF08511.6 EGC40036.1 - 3.3e-27 93.8 0.3 4.6e-27 93.3 0.2 1.2 1 0 0 1 1 1 1 COQ9 Pro_isomerase PF00160.16 EGC40037.1 - 1e-20 74.5 0.2 1.3e-20 74.2 0.1 1.1 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD BACON PF13004.2 EGC40037.1 - 0.0052 16.9 0.3 0.01 16.0 0.2 1.5 1 0 0 1 1 1 1 Bacteroidetes-Associated Carbohydrate-binding Often N-terminal Lectin_legB PF00139.14 EGC40038.1 - 5.7e-14 52.0 0.0 7.3e-14 51.7 0.0 1.1 1 0 0 1 1 1 1 Legume lectin domain Scramblase PF03803.10 EGC40039.1 - 0.0069 15.4 0.1 0.019 14.0 0.1 1.8 1 1 0 1 1 1 1 Scramblase CAP_C PF08603.6 EGC40039.1 - 0.26 10.6 4.4 0.19 11.0 0.2 2.7 2 2 0 3 3 3 0 Adenylate cyclase associated (CAP) C terminal MFS_1 PF07690.11 EGC40040.1 - 1.2e-30 106.3 10.6 1.2e-30 106.3 7.3 1.4 1 1 0 1 1 1 1 Major Facilitator Superfamily Epiglycanin_C PF14654.1 EGC40041.1 - 0.049 13.6 0.2 6.9 6.7 0.1 2.4 2 0 0 2 2 2 0 Mucin, catalytic, TM and cytoplasmic tail region PAS_3 PF08447.6 EGC40042.1 - 1.5e-10 41.0 0.0 2.9e-10 40.0 0.0 1.5 1 0 0 1 1 1 1 PAS fold PAS_9 PF13426.1 EGC40042.1 - 4.3e-05 23.8 0.0 0.00012 22.4 0.0 1.7 2 0 0 2 2 2 1 PAS domain Zn_clus PF00172.13 EGC40042.1 - 0.0028 17.5 5.0 0.0049 16.7 3.5 1.4 1 0 0 1 1 1 1 Fungal Zn(2)-Cys(6) binuclear cluster domain PAS PF00989.19 EGC40042.1 - 0.042 13.6 0.0 0.081 12.7 0.0 1.4 1 0 0 1 1 1 0 PAS fold TFIIA PF03153.8 EGC40042.1 - 0.32 10.8 29.0 0.19 11.5 5.5 2.3 2 0 0 2 2 2 0 Transcription factor IIA, alpha/beta subunit Tmemb_cc2 PF10267.4 EGC40042.1 - 0.72 8.3 11.9 0.016 13.8 2.7 2.0 2 0 0 2 2 2 0 Predicted transmembrane and coiled-coil 2 protein FANCL_C PF11793.3 EGC40043.1 - 2.6e-06 27.2 6.7 1.1e-05 25.3 4.7 2.1 1 0 0 1 1 1 1 FANCL C-terminal domain zf-RING_2 PF13639.1 EGC40043.1 - 5.2e-06 26.1 9.3 5.2e-06 26.1 6.4 2.0 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC40043.1 - 1.3e-05 25.2 6.4 3.1e-05 23.9 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-Apc11 PF12861.2 EGC40043.1 - 0.00096 18.9 5.6 0.0026 17.5 3.9 1.7 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger HEAT_2 PF13646.1 EGC40043.1 - 0.0095 16.1 0.0 1.8 8.8 0.0 3.5 2 1 0 2 2 2 1 HEAT repeats RINGv PF12906.2 EGC40043.1 - 0.028 14.4 8.3 0.075 13.0 5.7 1.8 1 0 0 1 1 1 0 RING-variant domain zf-C3HC4 PF00097.20 EGC40043.1 - 0.28 10.8 17.4 0.1 12.2 7.9 2.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) C1_1 PF00130.17 EGC40043.1 - 0.33 10.7 8.8 0.37 10.5 4.9 2.0 1 1 0 1 1 1 0 Phorbol esters/diacylglycerol binding domain (C1 domain) zf-C3HC4_2 PF13923.1 EGC40043.1 - 0.44 10.6 15.9 0.059 13.4 7.7 2.1 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) PHD PF00628.24 EGC40043.1 - 3 7.6 7.4 7.7 6.3 5.1 1.8 1 0 0 1 1 1 0 PHD-finger zf-RING-like PF08746.6 EGC40043.1 - 4.4 7.3 12.1 1.7 8.7 6.2 2.0 2 0 0 2 2 2 0 RING-like domain GATase_2 PF00310.16 EGC40044.1 - 5.7e-19 68.0 0.0 4.6e-15 55.1 0.0 2.4 1 1 1 2 2 2 2 Glutamine amidotransferases class-II GATase_7 PF13537.1 EGC40044.1 - 8.2e-16 57.8 0.0 1.4e-15 57.1 0.0 1.4 1 0 0 1 1 1 1 Glutamine amidotransferase domain Pribosyltran PF00156.22 EGC40044.1 - 1.5e-15 57.0 0.0 2.5e-15 56.2 0.0 1.4 1 0 0 1 1 1 1 Phosphoribosyl transferase domain GATase_6 PF13522.1 EGC40044.1 - 1.9e-15 57.0 0.0 3.3e-15 56.1 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferase domain GATase_4 PF13230.1 EGC40044.1 - 0.00042 19.0 0.0 0.00064 18.4 0.0 1.3 1 0 0 1 1 1 1 Glutamine amidotransferases class-II UPRTase PF14681.1 EGC40044.1 - 0.044 12.9 0.0 0.094 11.9 0.0 1.5 1 0 0 1 1 1 0 Uracil phosphoribosyltransferase PRTase_2 PF15609.1 EGC40044.1 - 0.06 12.6 0.1 0.23 10.7 0.0 2.1 3 0 0 3 3 3 0 Phosphoribosyl transferase DBC1 PF14443.1 EGC40045.1 - 1.2e-39 134.7 0.0 1.2e-39 134.7 0.0 2.8 2 1 0 2 2 2 1 DBC1 DUF936 PF06075.7 EGC40046.1 - 0.00099 18.1 29.6 0.0013 17.7 20.5 1.2 1 0 0 1 1 1 1 Plant protein of unknown function (DUF936) Trypan_PARP PF05887.6 EGC40046.1 - 0.0011 18.7 8.4 0.0011 18.7 5.8 2.2 2 0 0 2 2 2 1 Procyclic acidic repetitive protein (PARP) Daxx PF03344.10 EGC40046.1 - 7.8 4.8 47.5 13 4.1 32.9 1.3 1 0 0 1 1 1 0 Daxx Family CBS PF00571.23 EGC40047.1 - 8.8e-24 83.0 0.7 5.6e-07 29.2 0.0 4.2 4 0 0 4 4 4 4 CBS domain Actin PF00022.14 EGC40048.1 - 2.6e-151 503.5 0.0 2.9e-151 503.3 0.0 1.0 1 0 0 1 1 1 1 Actin Marek_SORF3 PF07153.6 EGC40048.1 - 0.08 11.5 0.0 0.13 10.9 0.0 1.2 1 0 0 1 1 1 0 Marek's disease-like virus SORF3 protein Actin PF00022.14 EGC40049.1 - 3e-143 476.9 0.0 3.7e-143 476.6 0.0 1.1 1 0 0 1 1 1 1 Actin Actin PF00022.14 EGC40050.1 - 3.8e-55 186.9 0.1 2.3e-44 151.4 0.0 2.0 1 1 1 2 2 2 2 Actin HypD PF01924.11 EGC40050.1 - 0.061 12.0 0.0 0.083 11.6 0.0 1.1 1 0 0 1 1 1 0 Hydrogenase formation hypA family DUF2404 PF10296.4 EGC40051.1 - 9.1e-05 22.5 0.1 0.00037 20.5 0.0 2.1 3 0 0 3 3 3 1 Putative integral membrane protein conserved region (DUF2404) Claudin_2 PF13903.1 EGC40052.1 - 0.0051 16.5 11.9 0.0079 15.8 7.6 1.8 1 1 0 1 1 1 1 PMP-22/EMP/MP20/Claudin tight junction CD20 PF04103.10 EGC40052.1 - 0.016 15.1 10.7 1.5 8.7 4.2 3.0 1 1 1 2 2 2 0 CD20-like family Tetraspannin PF00335.15 EGC40052.1 - 0.021 14.0 11.2 0.0051 16.1 5.5 1.6 1 1 0 1 1 1 0 Tetraspanin family NdhL PF10716.4 EGC40052.1 - 0.083 12.6 2.7 1.3 8.8 0.1 2.3 2 0 0 2 2 2 0 NADH dehydrogenase transmembrane subunit Fig1 PF12351.3 EGC40052.1 - 0.28 11.0 6.4 0.38 10.6 1.1 2.2 2 0 0 2 2 2 0 Ca2+ regulator and membrane fusion protein Fig1 DUF4097 PF13349.1 EGC40052.1 - 0.28 10.7 0.1 0.28 10.7 0.0 3.1 3 0 0 3 3 3 0 Domain of unknown function (DUF4097) DUF969 PF06149.7 EGC40052.1 - 0.51 9.5 6.8 0.059 12.6 1.2 1.9 2 1 1 3 3 3 0 Protein of unknown function (DUF969) HlyIII PF03006.15 EGC40052.1 - 0.67 9.3 12.9 7 5.9 0.1 2.5 2 1 0 2 2 2 0 Haemolysin-III related MARVEL PF01284.18 EGC40052.1 - 1.4 8.7 15.2 13 5.5 10.5 2.3 1 1 0 1 1 1 0 Membrane-associating domain CbiQ PF02361.11 EGC40052.1 - 1.4 8.4 9.5 0.094 12.2 2.8 1.7 2 0 0 2 2 2 0 Cobalt transport protein DUF898 PF05987.8 EGC40052.1 - 1.7 7.4 10.6 0.55 9.0 0.7 2.9 3 0 0 3 3 3 0 Bacterial protein of unknown function (DUF898) SUR7 PF06687.7 EGC40052.1 - 2.7 7.5 20.1 2.8 7.4 6.5 3.0 1 1 0 2 2 2 0 SUR7/PalI family TatC PF00902.13 EGC40052.1 - 3.4 7.0 13.7 19 4.5 9.5 2.1 1 1 0 1 1 1 0 Sec-independent protein translocase protein (TatC) Phage_holin_1 PF04531.8 EGC40052.1 - 6.4 6.9 11.1 2.3 8.3 1.0 3.1 2 1 1 3 3 3 0 Bacteriophage holin zf-DHHC PF01529.15 EGC40052.1 - 9 5.6 9.2 4.3 6.7 2.3 2.2 2 0 0 2 2 2 0 DHHC palmitoyltransferase Nucleoporin_FG PF13634.1 EGC40053.1 - 0.00081 19.5 21.8 0.00081 19.5 15.1 12.1 5 4 5 10 10 10 7 Nucleoporin FG repeat region Actin PF00022.14 EGC40054.1 - 2.1e-65 220.6 0.0 3.1e-65 220.1 0.0 1.2 1 0 0 1 1 1 1 Actin DUF1772 PF08592.6 EGC40055.1 - 1.5e-16 60.3 0.5 2e-16 59.9 0.2 1.2 1 1 0 1 1 1 1 Domain of unknown function (DUF1772) UPF0104 PF03706.8 EGC40055.1 - 0.11 11.7 6.1 0.04 13.1 2.5 1.5 1 1 0 1 1 1 0 Uncharacterised protein family (UPF0104) DUF2269 PF10027.4 EGC40055.1 - 0.34 10.6 4.9 0.58 9.9 3.4 1.6 1 1 0 1 1 1 0 Predicted integral membrane protein (DUF2269) DUF1772 PF08592.6 EGC40056.1 - 7.9e-23 80.7 0.0 1.1e-22 80.2 0.0 1.2 1 0 0 1 1 1 1 Domain of unknown function (DUF1772) SAP PF02037.22 EGC40057.1 - 5.5e-06 25.7 0.3 1.1e-05 24.8 0.2 1.5 1 0 0 1 1 1 1 SAP domain F-box-like PF12937.2 EGC40057.1 - 0.00065 19.3 0.0 0.0018 17.9 0.0 1.8 1 0 0 1 1 1 1 F-box-like F-box PF00646.28 EGC40057.1 - 0.027 14.1 0.3 0.11 12.1 0.1 2.2 2 0 0 2 2 2 0 F-box domain DNA_ligase_A_M PF01068.16 EGC40059.1 - 2.1e-61 206.8 0.1 3.3e-61 206.1 0.0 1.3 1 0 0 1 1 1 1 ATP dependent DNA ligase domain DNA_ligase_A_N PF04675.9 EGC40059.1 - 8.5e-46 155.9 0.1 1.3e-45 155.3 0.1 1.3 1 0 0 1 1 1 1 DNA ligase N terminus DNA_ligase_A_C PF04679.10 EGC40059.1 - 7.4e-26 90.3 0.0 2.3e-25 88.8 0.0 1.8 2 0 0 2 2 2 1 ATP dependent DNA ligase C terminal region DNA_ligase_OB_2 PF14743.1 EGC40059.1 - 0.003 17.1 0.1 0.71 9.5 0.0 2.5 2 0 0 2 2 2 2 DNA ligase OB-like domain Pex19 PF04614.7 EGC40060.1 - 2e-08 34.1 27.4 5.2e-08 32.7 14.1 3.0 1 1 1 2 2 2 1 Pex19 protein family Mito_fiss_reg PF05308.6 EGC40060.1 - 0.06 12.7 2.1 0.1 11.9 1.5 1.3 1 0 0 1 1 1 0 Mitochondrial fission regulator DUF2265 PF10023.4 EGC40060.1 - 0.41 9.7 3.5 0.39 9.8 0.1 2.0 2 0 0 2 2 2 0 Predicted aminopeptidase (DUF2265) PilX_N PF14341.1 EGC40060.1 - 1.7 8.3 4.7 3.1 7.5 3.2 1.3 1 0 0 1 1 1 0 PilX N-terminal Tir_receptor_C PF07489.6 EGC40060.1 - 2.1 8.0 9.2 3.5 7.3 6.4 1.3 1 0 0 1 1 1 0 Translocated intimin receptor (Tir) C-terminus SSP160 PF06933.6 EGC40060.1 - 2.9 5.7 11.2 4.2 5.2 7.8 1.2 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC40060.1 - 2.9 7.6 16.5 4.3 7.1 11.5 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein GRIM-19 PF06212.7 EGC40061.1 - 1.5e-15 57.0 0.0 2.5e-15 56.3 0.0 1.3 1 1 0 1 1 1 1 GRIM-19 protein NLPC_P60 PF00877.14 EGC40062.1 - 4.5e-13 48.9 0.6 7e-13 48.3 0.4 1.3 1 1 0 1 1 1 1 NlpC/P60 family Amidase_5 PF05382.8 EGC40062.1 - 0.095 12.3 3.1 0.23 11.0 2.1 1.8 1 1 0 1 1 1 0 Bacteriophage peptidoglycan hydrolase RNA_lig_T4_1 PF09511.5 EGC40063.1 - 7e-26 91.0 0.0 1.2e-25 90.2 0.0 1.5 1 1 0 1 1 1 1 RNA ligase LOH1CR12 PF10158.4 EGC40064.1 - 0.00013 21.8 4.9 0.00025 20.8 3.4 1.5 1 0 0 1 1 1 1 Tumour suppressor protein KcnmB2_inactiv PF09303.5 EGC40064.1 - 0.016 14.9 1.4 0.31 10.8 0.0 2.7 2 0 0 2 2 2 0 KCNMB2, ball and chain domain DUF1825 PF08855.5 EGC40064.1 - 0.021 14.8 3.5 0.43 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of unknown function (DUF1825) ISG65-75 PF11727.3 EGC40064.1 - 0.52 9.3 4.1 1.1 8.2 2.8 1.5 1 0 0 1 1 1 0 Invariant surface glycoprotein p450 PF00067.17 EGC40065.1 - 1.2e-32 113.0 0.0 1.4e-32 112.8 0.0 1.0 1 0 0 1 1 1 1 Cytochrome P450 DUP PF00674.13 EGC40066.1 - 0.048 13.6 2.5 0.1 12.5 0.1 2.4 1 1 0 2 2 2 0 DUP family DUF4191 PF13829.1 EGC40066.1 - 0.5 9.4 2.4 0.7 8.9 1.7 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) Phlebovirus_G1 PF07243.6 EGC40066.1 - 0.92 7.5 3.4 1.2 7.1 2.3 1.2 1 0 0 1 1 1 0 Phlebovirus glycoprotein G1 DPM3 PF08285.6 EGC40066.1 - 1.3 8.8 5.4 2.3 8.1 3.7 1.4 1 0 0 1 1 1 0 Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) Erf4 PF10256.4 EGC40067.1 - 0.0035 17.1 0.8 0.0099 15.7 0.6 1.8 1 1 0 1 1 1 1 Golgin subfamily A member 7/ERF4 family Sulfate_transp PF00916.15 EGC40067.1 - 0.057 12.4 2.0 0.084 11.8 1.4 1.2 1 0 0 1 1 1 0 Sulfate transporter family DUF4234 PF14018.1 EGC40067.1 - 1.5 8.5 6.9 92 2.8 4.8 2.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4234) C2 PF00168.25 EGC40068.1 - 6e-22 77.2 0.0 9.5e-22 76.6 0.0 1.3 1 0 0 1 1 1 1 C2 domain ERK-JNK_inhib PF15002.1 EGC40068.1 - 0.037 13.3 0.1 0.058 12.7 0.1 1.2 1 0 0 1 1 1 0 ERK and JNK pathways, inhibitor AAA_16 PF13191.1 EGC40069.1 - 8.9e-12 45.3 0.0 3.2e-11 43.5 0.0 2.0 1 0 0 1 1 1 1 AAA ATPase domain AAA_22 PF13401.1 EGC40069.1 - 0.0037 17.4 0.0 0.072 13.2 0.0 3.0 1 1 0 1 1 1 1 AAA domain DUF1014 PF06244.7 EGC40070.1 - 4.3e-33 114.1 5.7 4.3e-33 114.1 4.0 3.4 1 1 1 2 2 2 1 Protein of unknown function (DUF1014) PLRV_ORF5 PF01690.12 EGC40070.1 - 0.39 9.8 18.1 0.47 9.5 12.5 1.1 1 0 0 1 1 1 0 Potato leaf roll virus readthrough protein SDH_alpha PF03313.10 EGC40070.1 - 5.9 5.8 7.3 8.2 5.3 5.0 1.2 1 0 0 1 1 1 0 Serine dehydratase alpha chain cobW PF02492.14 EGC40071.1 - 1e-41 142.3 2.1 2.1e-41 141.2 1.5 1.5 1 1 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain CobW_C PF07683.9 EGC40071.1 - 2.7e-23 81.4 0.0 5.9e-23 80.4 0.0 1.6 1 0 0 1 1 1 1 Cobalamin synthesis protein cobW C-terminal domain MobB PF03205.9 EGC40071.1 - 0.0094 15.6 0.2 0.028 14.1 0.1 1.9 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B SRP54 PF00448.17 EGC40071.1 - 0.011 15.2 0.0 0.019 14.4 0.0 1.4 1 0 0 1 1 1 0 SRP54-type protein, GTPase domain T2SE PF00437.15 EGC40071.1 - 0.012 14.5 0.0 0.018 13.9 0.0 1.3 1 0 0 1 1 1 0 Type II/IV secretion system protein GTP_EFTU PF00009.22 EGC40071.1 - 0.015 14.7 0.1 1.2 8.5 0.0 2.5 2 0 0 2 2 2 0 Elongation factor Tu GTP binding domain MMR_HSR1 PF01926.18 EGC40071.1 - 0.016 15.1 0.1 0.038 13.9 0.1 1.8 1 0 0 1 1 1 0 50S ribosome-binding GTPase Zeta_toxin PF06414.7 EGC40071.1 - 0.019 14.0 0.0 1.9 7.5 0.0 2.3 1 1 1 2 2 2 0 Zeta toxin Arch_ATPase PF01637.13 EGC40071.1 - 0.022 14.4 0.0 0.044 13.4 0.0 1.6 1 0 0 1 1 1 0 Archaeal ATPase AAA_22 PF13401.1 EGC40071.1 - 0.029 14.5 0.0 0.06 13.4 0.0 1.5 1 0 0 1 1 1 0 AAA domain NB-ARC PF00931.17 EGC40071.1 - 0.052 12.3 0.8 0.078 11.8 0.0 1.7 2 0 0 2 2 2 0 NB-ARC domain Viral_helicase1 PF01443.13 EGC40071.1 - 0.055 12.9 0.0 0.1 12.1 0.0 1.4 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase AAA_18 PF13238.1 EGC40071.1 - 0.075 13.3 2.3 0.13 12.5 0.1 2.5 2 1 0 2 2 2 0 AAA domain AAA_17 PF13207.1 EGC40071.1 - 0.15 12.8 0.6 0.47 11.2 0.1 2.3 2 1 0 2 2 1 0 AAA domain AAA_33 PF13671.1 EGC40071.1 - 0.18 11.6 0.0 0.35 10.7 0.0 1.5 1 0 0 1 1 1 0 AAA domain NodZ PF05830.6 EGC40072.1 - 0.021 13.4 0.0 0.033 12.7 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein Z (NodZ) SLT PF01464.15 EGC40073.1 - 2.8e-11 42.9 0.0 3.9e-11 42.4 0.0 1.2 1 0 0 1 1 1 1 Transglycosylase SLT domain Lys PF00062.15 EGC40073.1 - 0.001 19.0 1.3 0.026 14.5 0.9 2.1 1 1 0 1 1 1 1 C-type lysozyme/alpha-lactalbumin family Cofilin_ADF PF00241.15 EGC40074.1 - 8.5e-26 90.3 3.6 4.8e-13 49.1 0.1 2.2 2 0 0 2 2 2 2 Cofilin/tropomyosin-type actin-binding protein Autoind_bind PF03472.10 EGC40074.1 - 0.072 12.3 0.0 0.12 11.6 0.0 1.3 1 0 0 1 1 1 0 Autoinducer binding domain Ribosomal_L2_C PF03947.13 EGC40075.1 - 5.1e-39 133.0 2.0 7.9e-39 132.4 1.4 1.3 1 0 0 1 1 1 1 Ribosomal Proteins L2, C-terminal domain Ribosomal_L2 PF00181.18 EGC40075.1 - 7.7e-19 67.4 0.0 1.8e-18 66.2 0.0 1.7 1 0 0 1 1 1 1 Ribosomal Proteins L2, RNA binding domain PRP3 PF08572.5 EGC40077.1 - 2.4e-56 190.5 15.0 2.4e-56 190.5 10.4 2.5 2 0 0 2 2 2 1 pre-mRNA processing factor 3 (PRP3) DUF1115 PF06544.7 EGC40077.1 - 6.9e-33 113.0 0.1 6.9e-33 113.0 0.0 3.9 3 1 1 4 4 4 1 Protein of unknown function (DUF1115) Myosin_head PF00063.16 EGC40078.1 - 2.2e-248 825.8 8.7 2.2e-248 825.8 6.0 2.3 2 0 0 2 2 1 1 Myosin head (motor domain) MyTH4 PF00784.12 EGC40078.1 - 3.7e-64 213.8 5.9 2.1e-33 114.6 0.8 3.4 2 0 0 2 2 2 2 MyTH4 domain RA PF00788.18 EGC40078.1 - 4.7e-11 43.0 0.2 5.8e-06 26.7 0.1 4.3 3 0 0 3 3 3 2 Ras association (RalGDS/AF-6) domain SH3_2 PF07653.12 EGC40078.1 - 1.4e-09 37.2 0.0 3e-09 36.2 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain SH3_9 PF14604.1 EGC40078.1 - 4.2e-07 29.4 0.0 9e-07 28.3 0.0 1.6 1 0 0 1 1 1 1 Variant SH3 domain FERM_C PF09380.5 EGC40078.1 - 4.4e-07 30.0 3.0 0.00029 20.9 0.2 3.4 2 0 0 2 2 2 2 FERM C-terminal PH-like domain SH3_1 PF00018.23 EGC40078.1 - 1.1e-06 27.8 0.0 3.2e-06 26.4 0.0 1.8 1 0 0 1 1 1 1 SH3 domain FERM_N PF09379.5 EGC40078.1 - 0.0016 18.4 0.2 0.011 15.7 0.2 2.6 2 0 0 2 2 2 1 FERM N-terminal domain IQ PF00612.22 EGC40078.1 - 0.0035 16.8 15.4 0.036 13.7 1.2 4.1 4 0 0 4 4 3 2 IQ calmodulin-binding motif AAA_16 PF13191.1 EGC40078.1 - 0.016 15.1 0.0 0.14 12.1 0.0 2.6 2 0 0 2 2 2 0 AAA ATPase domain AAA_22 PF13401.1 EGC40078.1 - 0.02 14.9 0.0 0.23 11.5 0.0 2.7 2 0 0 2 2 2 0 AAA domain SprA-related PF12118.3 EGC40078.1 - 3.5 6.8 23.6 8.7 5.5 16.4 1.6 1 0 0 1 1 1 0 SprA-related family Fascin PF06268.8 EGC40079.1 - 2.5e-16 59.7 1.7 7.3e-10 38.9 0.1 2.0 1 1 1 2 2 2 2 Fascin domain FRG1 PF06229.7 EGC40079.1 - 4.1e-06 26.3 0.5 0.016 14.6 0.2 3.0 1 1 1 2 2 2 2 FRG1-like family FGF PF00167.13 EGC40079.1 - 3.8e-05 23.4 0.2 0.00022 20.9 0.0 1.9 1 1 1 2 2 2 2 Fibroblast growth factor DUF569 PF04601.8 EGC40079.1 - 0.011 15.1 0.2 0.055 12.8 0.1 1.9 1 1 1 2 2 2 0 Protein of unknown function (DUF569) SNF2_assoc PF08455.5 EGC40079.1 - 0.028 12.9 0.0 0.032 12.8 0.0 1.1 1 0 0 1 1 1 0 Bacterial SNF2 helicase associated DUF3216 PF11505.3 EGC40080.1 - 0.089 12.5 0.1 0.17 11.7 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3216) DUF31 PF01732.11 EGC40080.1 - 0.3 10.3 15.3 10 5.3 0.1 3.5 1 1 2 3 3 3 0 Putative peptidase (DUF31) Pro_CA PF00484.14 EGC40081.1 - 2.5e-48 163.9 0.0 3.5e-48 163.4 0.0 1.2 1 0 0 1 1 1 1 Carbonic anhydrase EF-hand_6 PF13405.1 EGC40082.1 - 2.2e-10 39.5 9.3 0.0018 18.0 0.5 4.8 5 0 0 5 5 5 3 EF-hand domain EF-hand_7 PF13499.1 EGC40082.1 - 7.2e-09 35.6 5.6 9.6e-06 25.6 2.0 2.7 1 1 0 2 2 2 2 EF-hand domain pair EF-hand_1 PF00036.27 EGC40082.1 - 1.6e-08 33.2 8.4 0.0036 16.4 0.7 4.4 5 0 0 5 5 5 2 EF hand EF-hand_8 PF13833.1 EGC40082.1 - 1.9e-06 27.4 3.4 0.022 14.3 0.4 3.4 2 1 1 3 3 3 2 EF-hand domain pair SPARC_Ca_bdg PF10591.4 EGC40082.1 - 0.00085 19.3 2.3 0.64 10.0 0.0 2.6 2 1 0 2 2 2 2 Secreted protein acidic and rich in cysteine Ca binding region EF-hand_4 PF12763.2 EGC40082.1 - 0.0019 17.8 1.6 0.0019 17.8 1.1 1.7 2 1 1 3 3 3 1 Cytoskeletal-regulatory complex EF hand Pam16 PF03656.8 EGC40082.1 - 0.24 11.1 3.1 0.77 9.5 0.6 2.1 2 0 0 2 2 2 0 Pam16 EF-hand_10 PF14788.1 EGC40082.1 - 3 7.5 8.4 4.7 6.9 2.3 3.5 3 1 0 3 3 3 0 EF hand EF-hand_5 PF13202.1 EGC40082.1 - 3.5 7.1 18.8 0.21 10.9 1.0 3.9 4 1 1 5 5 5 0 EF hand IP_trans PF02121.13 EGC40083.1 - 4.4e-99 330.7 0.5 5.1e-99 330.5 0.3 1.0 1 0 0 1 1 1 1 Phosphatidylinositol transfer protein Bromodomain PF00439.20 EGC40084.1 - 8.2e-23 80.1 2.4 8.2e-23 80.1 1.6 2.3 2 0 0 2 2 2 1 Bromodomain Patched PF02460.13 EGC40084.1 - 3.9 5.2 12.8 6.6 4.4 8.9 1.4 1 0 0 1 1 1 0 Patched family COX_ARM PF06481.9 EGC40085.1 - 0.11 12.1 1.8 5.4 6.7 0.1 2.9 1 1 2 3 3 3 0 COX Aromatic Rich Motif DUF1673 PF07895.6 EGC40085.1 - 3.6 7.0 7.9 2 7.9 2.9 2.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1673) AAA_12 PF13087.1 EGC40086.1 - 1.3e-29 103.0 0.0 7.1e-29 100.6 0.0 2.4 1 0 0 1 1 1 1 AAA domain AAA_11 PF13086.1 EGC40086.1 - 8.7e-27 94.2 7.2 1.4e-26 93.4 1.8 3.5 2 1 0 2 2 2 1 AAA domain AAA_19 PF13245.1 EGC40086.1 - 2.6e-09 36.6 0.0 5e-09 35.7 0.0 1.4 1 0 0 1 1 1 1 Part of AAA domain AAA_30 PF13604.1 EGC40086.1 - 1.4e-06 28.0 0.0 0.0032 17.0 0.0 2.3 2 0 0 2 2 2 2 AAA domain Viral_helicase1 PF01443.13 EGC40086.1 - 3.9e-05 23.2 0.0 0.85 9.0 0.0 3.8 3 0 0 3 3 3 2 Viral (Superfamily 1) RNA helicase ResIII PF04851.10 EGC40086.1 - 4.4e-05 23.3 0.2 4.4e-05 23.3 0.1 2.7 2 0 0 2 2 2 1 Type III restriction enzyme, res subunit AAA_25 PF13481.1 EGC40086.1 - 0.00012 21.5 0.0 0.00025 20.5 0.0 1.4 1 0 0 1 1 1 1 AAA domain DEAD PF00270.24 EGC40086.1 - 0.00032 20.2 0.0 0.001 18.5 0.0 1.9 1 0 0 1 1 1 1 DEAD/DEAH box helicase KaiC PF06745.8 EGC40086.1 - 0.00086 18.4 0.0 0.0033 16.5 0.0 2.0 1 0 0 1 1 1 1 KaiC UvrD_C_2 PF13538.1 EGC40086.1 - 0.0012 18.9 0.1 0.027 14.6 0.0 3.0 2 0 0 2 2 2 1 UvrD-like helicase C-terminal domain AAA_16 PF13191.1 EGC40086.1 - 0.005 16.8 0.0 0.56 10.1 0.0 2.7 2 0 0 2 2 2 1 AAA ATPase domain TIP49 PF06068.8 EGC40086.1 - 0.0062 15.2 0.2 0.057 12.1 0.0 2.3 2 0 0 2 2 2 1 TIP49 C-terminus PhoH PF02562.11 EGC40086.1 - 0.0065 15.7 0.0 0.014 14.6 0.0 1.5 1 0 0 1 1 1 1 PhoH-like protein AAA PF00004.24 EGC40086.1 - 0.0071 16.5 0.0 0.025 14.7 0.0 2.0 1 0 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC40086.1 - 0.028 14.5 0.0 0.13 12.4 0.0 2.1 1 0 0 1 1 1 0 AAA domain AAA_17 PF13207.1 EGC40086.1 - 0.094 13.5 0.3 1.4 9.7 0.1 3.3 2 1 0 2 2 2 0 AAA domain AAA_33 PF13671.1 EGC40086.1 - 0.2 11.5 0.1 0.66 9.8 0.0 1.9 2 0 0 2 2 2 0 AAA domain FtsK_SpoIIIE PF01580.13 EGC40086.1 - 0.32 10.4 0.0 0.56 9.6 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family ATP-synt_D PF01813.12 EGC40087.1 - 5.2e-66 221.9 4.6 7.1e-66 221.5 3.2 1.2 1 0 0 1 1 1 1 ATP synthase subunit D TMP_2 PF06791.8 EGC40087.1 - 0.014 14.9 2.1 0.022 14.3 0.4 1.9 1 1 1 2 2 2 0 Prophage tail length tape measure protein Ret_tiss PF10044.4 EGC40088.1 - 2.9e-05 24.4 0.1 4.5e-05 23.9 0.1 1.3 1 0 0 1 1 1 1 Retinal tissue protein Gluconate_2-dh3 PF13618.1 EGC40088.1 - 0.042 13.9 0.0 0.042 13.9 0.0 1.1 1 0 0 1 1 1 0 Gluconate 2-dehydrogenase subunit 3 Cyclin_N PF00134.18 EGC40093.1 - 0.078 12.5 2.4 0.075 12.6 0.7 1.7 2 0 0 2 2 2 0 Cyclin, N-terminal domain DUF2890 PF11081.3 EGC40094.1 - 0.013 15.5 4.4 0.013 15.5 3.1 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF2890) RAMPs PF03787.10 EGC40094.1 - 0.13 12.0 3.5 0.17 11.6 2.4 1.1 1 0 0 1 1 1 0 RAMP superfamily Nucleoplasmin PF03066.10 EGC40094.1 - 2.5 7.5 9.2 4.4 6.8 6.3 1.4 1 0 0 1 1 1 0 Nucleoplasmin DUF1758 PF05585.7 EGC40096.1 - 0.055 13.0 0.2 0.076 12.5 0.2 1.3 1 0 0 1 1 1 0 Putative peptidase (DUF1758) Mob_Pre PF01076.14 EGC40096.1 - 0.12 12.0 9.2 0.02 14.5 1.9 2.1 2 0 0 2 2 2 0 Plasmid recombination enzyme Utp11 PF03998.8 EGC40096.1 - 0.38 10.5 3.6 0.44 10.3 2.5 1.1 1 0 0 1 1 1 0 Utp11 protein ORC6 PF05460.8 EGC40096.1 - 0.86 8.6 12.7 0.96 8.4 8.8 1.3 1 0 0 1 1 1 0 Origin recognition complex subunit 6 (ORC6) ABC2_membrane_3 PF12698.2 EGC40096.1 - 1.5 7.7 7.1 1.8 7.5 4.9 1.1 1 0 0 1 1 1 0 ABC-2 family transporter protein Radical_SAM PF04055.16 EGC40098.1 - 2.9e-09 37.3 0.1 7.9e-09 35.8 0.1 1.8 1 1 0 1 1 1 1 Radical SAM superfamily Fer4_14 PF13394.1 EGC40098.1 - 1e-06 28.7 0.0 2.4e-06 27.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain Fer4_12 PF13353.1 EGC40098.1 - 0.00034 20.7 0.1 0.0008 19.5 0.0 1.6 1 0 0 1 1 1 1 4Fe-4S single cluster domain DUF1793 PF08760.6 EGC40098.1 - 0.14 12.0 0.0 8 6.2 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF1793) P2X_receptor PF00864.14 EGC40099.1 - 7.8e-23 80.7 2.2 7.8e-12 44.5 0.4 2.3 1 1 1 2 2 2 2 ATP P2X receptor DUF3206 PF11472.3 EGC40100.1 - 0.035 13.8 0.1 0.073 12.8 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF3206) Glutaredoxin PF00462.19 EGC40101.1 - 1.8e-17 63.0 0.0 2.8e-17 62.4 0.0 1.3 1 0 0 1 1 1 1 Glutaredoxin Peptidase_S28 PF05577.7 EGC40102.1 - 1.4e-117 392.9 3.1 1.7e-117 392.6 2.1 1.0 1 0 0 1 1 1 1 Serine carboxypeptidase S28 Abhydrolase_1 PF00561.15 EGC40102.1 - 4.8e-05 23.0 0.0 8.2e-05 22.2 0.0 1.5 1 0 0 1 1 1 1 alpha/beta hydrolase fold Peptidase_S9 PF00326.16 EGC40102.1 - 9.5e-05 21.7 0.0 0.00016 20.9 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_6 PF12697.2 EGC40102.1 - 0.00014 21.8 0.0 0.00089 19.2 0.0 1.9 1 1 1 2 2 2 1 Alpha/beta hydrolase family Peptidase_S37 PF05576.6 EGC40102.1 - 0.0047 15.4 0.3 0.0071 14.8 0.2 1.2 1 0 0 1 1 1 1 PS-10 peptidase S37 Choline_transpo PF04515.7 EGC40103.1 - 5.3e-51 173.3 28.5 6.8e-50 169.6 19.7 2.2 1 1 0 1 1 1 1 Plasma-membrane choline transporter Sulfotransfer_2 PF03567.9 EGC40104.1 - 1.2e-07 31.7 1.3 1.2e-07 31.7 0.9 3.1 2 1 0 2 2 2 1 Sulfotransferase family Folate_carrier PF01770.13 EGC40104.1 - 0.27 9.7 2.5 0.4 9.1 1.7 1.3 1 0 0 1 1 1 0 Reduced folate carrier DUF3439 PF11921.3 EGC40105.1 - 0.11 12.2 4.8 0.11 12.2 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) DUF2935 PF11155.3 EGC40107.1 - 0.00048 20.2 2.2 0.001 19.1 1.5 1.6 1 0 0 1 1 1 1 Domain of unknown function (DUF2935) Oxidored_molyb PF00174.14 EGC40108.1 - 1.8e-53 180.4 0.0 2.4e-53 179.9 0.0 1.2 1 0 0 1 1 1 1 Oxidoreductase molybdopterin binding domain Mo-co_dimer PF03404.11 EGC40108.1 - 2.9e-33 114.3 0.0 6e-33 113.2 0.0 1.5 1 0 0 1 1 1 1 Mo-co oxidoreductase dimerisation domain GTP_EFTU PF00009.22 EGC40109.1 - 5.7e-31 107.4 0.1 1.9e-30 105.6 0.1 1.9 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain IF-2 PF11987.3 EGC40109.1 - 7e-13 48.4 1.3 7e-13 48.4 0.9 2.5 2 0 0 2 2 2 1 Translation-initiation factor 2 GTP_EFTU_D2 PF03144.20 EGC40109.1 - 3.1e-12 46.4 2.4 3.2e-08 33.5 0.1 2.9 2 0 0 2 2 2 2 Elongation factor Tu domain 2 MMR_HSR1 PF01926.18 EGC40109.1 - 5.2e-08 32.8 0.0 2e-07 30.9 0.0 2.1 1 0 0 1 1 1 1 50S ribosome-binding GTPase GTP_EFTU_D4 PF14578.1 EGC40109.1 - 4.5e-07 29.4 0.1 1.4e-06 27.8 0.1 1.8 1 0 0 1 1 1 1 Elongation factor Tu domain 4 Miro PF08477.8 EGC40109.1 - 2.8e-05 24.6 0.0 0.00012 22.5 0.0 2.1 1 0 0 1 1 1 1 Miro-like protein AAA_22 PF13401.1 EGC40109.1 - 0.0001 22.4 0.1 0.00036 20.6 0.0 1.9 2 0 0 2 2 2 1 AAA domain Mitofilin PF09731.4 EGC40109.1 - 0.00014 20.7 9.3 0.00022 20.0 6.4 1.5 1 0 0 1 1 1 1 Mitochondrial inner membrane protein ATP_bind_1 PF03029.12 EGC40109.1 - 0.00085 18.9 0.0 0.0035 16.9 0.0 2.0 1 1 0 1 1 1 1 Conserved hypothetical ATP binding protein SRPRB PF09439.5 EGC40109.1 - 0.0073 15.5 0.0 0.039 13.1 0.0 2.3 1 1 0 1 1 1 1 Signal recognition particle receptor beta subunit Ras PF00071.17 EGC40109.1 - 0.012 14.9 0.1 0.1 11.9 0.0 2.7 2 1 0 2 2 2 0 Ras family FeoB_N PF02421.13 EGC40109.1 - 0.041 13.1 0.5 0.33 10.2 0.1 2.8 2 2 1 3 3 3 0 Ferrous iron transport protein B Dynamin_N PF00350.18 EGC40109.1 - 0.5 10.1 6.5 13 5.6 0.0 3.5 2 1 1 3 3 3 0 Dynamin family Daxx PF03344.10 EGC40109.1 - 2.2 6.6 17.4 3 6.2 12.1 1.1 1 0 0 1 1 1 0 Daxx Family DDRGK PF09756.4 EGC40109.1 - 8.4 5.7 16.3 9 5.6 9.4 2.1 2 0 0 2 2 2 0 DDRGK domain Spore_coat_CotO PF14153.1 EGC40110.1 - 0.055 12.9 2.2 0.056 12.8 1.5 1.1 1 0 0 1 1 1 0 Spore coat protein CotO CDC45 PF02724.9 EGC40110.1 - 0.23 9.4 14.1 0.22 9.5 9.8 1.0 1 0 0 1 1 1 0 CDC45-like protein Cwf_Cwc_15 PF04889.7 EGC40110.1 - 0.24 11.0 16.2 0.25 10.9 11.2 1.0 1 0 0 1 1 1 0 Cwf15/Cwc15 cell cycle control protein DUF1754 PF08555.5 EGC40110.1 - 0.47 11.0 7.4 0.59 10.7 5.1 1.2 1 0 0 1 1 1 0 Eukaryotic family of unknown function (DUF1754) DUF1510 PF07423.6 EGC40110.1 - 0.86 8.9 10.1 0.84 8.9 7.0 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) Nop14 PF04147.7 EGC40110.1 - 0.89 7.3 19.7 0.8 7.5 13.6 1.0 1 0 0 1 1 1 0 Nop14-like family DNA_pol_phi PF04931.8 EGC40110.1 - 1.1 6.9 22.1 1.2 6.8 15.3 1.0 1 0 0 1 1 1 0 DNA polymerase phi Nucleo_P87 PF07267.6 EGC40110.1 - 1.2 7.7 7.2 1.2 7.7 5.0 1.1 1 0 0 1 1 1 0 Nucleopolyhedrovirus capsid protein P87 Ebola_NP PF05505.7 EGC40110.1 - 1.3 6.9 9.5 1.3 7.0 6.6 1.0 1 0 0 1 1 1 0 Ebola nucleoprotein SDA1 PF05285.7 EGC40110.1 - 1.5 8.0 17.0 1.5 8.0 11.8 1.0 1 0 0 1 1 1 0 SDA1 Polyoma_lg_T_C PF06431.6 EGC40110.1 - 1.6 7.2 6.1 1.6 7.2 4.2 1.0 1 0 0 1 1 1 0 Polyomavirus large T antigen C-terminus CAF1A PF12253.3 EGC40110.1 - 2 8.5 15.6 2.9 8.0 10.8 1.3 1 0 0 1 1 1 0 Chromatin assembly factor 1 subunit A BUD22 PF09073.5 EGC40110.1 - 2.6 7.0 17.0 2.9 6.8 11.8 1.1 1 0 0 1 1 1 0 BUD22 Daxx PF03344.10 EGC40110.1 - 2.8 6.3 13.6 2.5 6.4 9.4 1.0 1 0 0 1 1 1 0 Daxx Family Na_trans_assoc PF06512.8 EGC40110.1 - 3.8 7.4 11.5 3.8 7.4 8.0 1.1 1 0 0 1 1 1 0 Sodium ion transport-associated TRAP_alpha PF03896.11 EGC40110.1 - 4.6 6.1 10.1 4.7 6.1 7.0 1.1 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit SURF2 PF05477.6 EGC40110.1 - 5.3 6.0 10.4 5.3 6.0 7.2 1.1 1 0 0 1 1 1 0 Surfeit locus protein 2 (SURF2) Sigma70_ner PF04546.8 EGC40110.1 - 5.5 6.5 12.7 6.2 6.3 8.8 1.2 1 0 0 1 1 1 0 Sigma-70, non-essential region DUF2457 PF10446.4 EGC40110.1 - 7.2 5.2 19.5 7.9 5.0 13.5 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) MBOAT PF03062.14 EGC40111.1 - 1.5e-51 175.4 6.1 1.5e-51 175.4 4.3 2.1 2 1 1 3 3 3 1 MBOAT, membrane-bound O-acyltransferase family CcmH PF03918.9 EGC40111.1 - 0.25 10.3 0.7 6.7 5.7 0.0 3.2 4 0 0 4 4 4 0 Cytochrome C biogenesis protein Ribosomal_L18p PF00861.17 EGC40112.1 - 1.1e-41 141.8 0.4 1.1e-41 141.8 0.3 2.3 3 0 0 3 3 3 1 Ribosomal L18p/L5e family Ribosomal_L18_c PF14204.1 EGC40112.1 - 4.6e-31 107.2 4.5 4.6e-31 107.2 3.1 1.8 2 0 0 2 2 2 1 Ribosomal L18 C-terminal region Thr_synth_N PF14821.1 EGC40112.1 - 0.054 13.5 0.2 0.54 10.3 0.0 2.3 1 1 1 2 2 2 0 Threonine synthase N terminus DIOX_N PF14226.1 EGC40113.1 - 7.1e-23 81.3 0.0 1.5e-22 80.2 0.0 1.5 1 0 0 1 1 1 1 non-haem dioxygenase in morphine synthesis N-terminal 2OG-FeII_Oxy PF03171.15 EGC40113.1 - 3.8e-17 62.3 0.0 6.6e-17 61.6 0.0 1.3 1 0 0 1 1 1 1 2OG-Fe(II) oxygenase superfamily DUF2479 PF10651.4 EGC40113.1 - 0.018 14.5 0.1 0.029 13.9 0.1 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF2479) AAA PF00004.24 EGC40114.1 - 6.1e-32 110.5 0.1 1.5e-31 109.2 0.0 1.7 2 0 0 2 2 1 1 ATPase family associated with various cellular activities (AAA) AAA_22 PF13401.1 EGC40114.1 - 2.8e-08 33.9 0.0 7.2e-08 32.6 0.0 1.7 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGC40114.1 - 6e-07 29.0 0.2 0.0025 17.2 0.0 2.3 1 1 1 2 2 2 2 AAA domain AAA_17 PF13207.1 EGC40114.1 - 7.5e-07 29.9 0.0 1.5e-06 29.0 0.0 1.6 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGC40114.1 - 1.9e-06 27.7 5.6 2.8e-05 23.9 0.9 3.0 2 1 0 2 2 2 1 Archaeal ATPase AAA_18 PF13238.1 EGC40114.1 - 2.4e-06 27.8 0.1 6.8e-06 26.4 0.0 1.9 2 1 0 2 2 1 1 AAA domain AAA_14 PF13173.1 EGC40114.1 - 4.3e-06 26.6 2.7 1.5e-05 24.8 0.0 2.6 2 1 1 3 3 3 1 AAA domain AAA_5 PF07728.9 EGC40114.1 - 5e-06 26.2 0.2 2.5e-05 24.0 0.0 2.3 2 1 0 2 2 1 1 AAA domain (dynein-related subfamily) KAP_NTPase PF07693.9 EGC40114.1 - 2.6e-05 23.3 1.9 0.11 11.4 0.6 2.5 1 1 1 2 2 2 2 KAP family P-loop domain AAA_16 PF13191.1 EGC40114.1 - 0.00011 22.3 0.0 0.00041 20.3 0.0 1.9 1 1 0 1 1 1 1 AAA ATPase domain AAA_24 PF13479.1 EGC40114.1 - 0.00012 21.7 0.5 0.00034 20.2 0.4 1.9 1 1 0 1 1 1 1 AAA domain AAA_2 PF07724.9 EGC40114.1 - 0.00018 21.4 0.1 0.0012 18.8 0.0 2.1 1 1 0 1 1 1 1 AAA domain (Cdc48 subfamily) RNA_helicase PF00910.17 EGC40114.1 - 0.00021 21.4 0.2 0.00077 19.6 0.0 2.1 2 0 0 2 2 1 1 RNA helicase IstB_IS21 PF01695.12 EGC40114.1 - 0.00026 20.4 0.0 0.00076 18.9 0.0 1.8 1 0 0 1 1 1 1 IstB-like ATP binding protein NACHT PF05729.7 EGC40114.1 - 0.00036 20.2 0.3 0.0012 18.5 0.0 2.0 2 1 0 2 2 2 1 NACHT domain PhoH PF02562.11 EGC40114.1 - 0.00045 19.4 0.2 0.0022 17.2 0.0 2.1 2 0 0 2 2 2 1 PhoH-like protein NB-ARC PF00931.17 EGC40114.1 - 0.00077 18.4 0.1 0.0024 16.7 0.0 1.9 2 0 0 2 2 2 1 NB-ARC domain AAA_19 PF13245.1 EGC40114.1 - 0.00077 19.1 0.0 0.0035 17.0 0.0 1.9 2 0 0 2 2 2 1 Part of AAA domain Zeta_toxin PF06414.7 EGC40114.1 - 0.00088 18.4 0.0 0.0021 17.1 0.0 1.6 1 0 0 1 1 1 1 Zeta toxin AAA_33 PF13671.1 EGC40114.1 - 0.00092 19.1 0.0 0.0017 18.2 0.0 1.6 1 1 0 1 1 1 1 AAA domain UPF0079 PF02367.12 EGC40114.1 - 0.0013 18.3 0.0 0.0027 17.3 0.0 1.5 1 0 0 1 1 1 1 Uncharacterised P-loop hydrolase UPF0079 RuvB_N PF05496.7 EGC40114.1 - 0.0015 17.6 0.2 0.0053 15.8 0.0 1.9 2 1 1 3 3 2 1 Holliday junction DNA helicase ruvB N-terminus AAA_11 PF13086.1 EGC40114.1 - 0.0017 17.9 0.2 0.0087 15.6 0.0 2.0 2 0 0 2 2 2 1 AAA domain DUF815 PF05673.8 EGC40114.1 - 0.0018 17.2 0.0 0.026 13.4 0.0 2.3 2 0 0 2 2 2 1 Protein of unknown function (DUF815) AAA_28 PF13521.1 EGC40114.1 - 0.0021 18.0 0.0 0.0037 17.2 0.0 1.4 1 0 0 1 1 1 1 AAA domain PIF1 PF05970.9 EGC40114.1 - 0.0027 16.6 0.3 0.012 14.6 0.0 2.0 2 0 0 2 2 2 1 PIF1-like helicase Sigma54_activ_2 PF14532.1 EGC40114.1 - 0.0027 17.7 0.0 0.0065 16.5 0.0 1.7 1 0 0 1 1 1 1 Sigma-54 interaction domain TIP49 PF06068.8 EGC40114.1 - 0.0029 16.3 0.1 0.011 14.4 0.0 2.0 2 0 0 2 2 2 1 TIP49 C-terminus Mg_chelatase PF01078.16 EGC40114.1 - 0.0036 16.4 0.0 0.0067 15.6 0.0 1.4 1 0 0 1 1 1 1 Magnesium chelatase, subunit ChlI SKI PF01202.17 EGC40114.1 - 0.0047 16.8 0.1 0.012 15.4 0.0 1.8 2 0 0 2 2 1 1 Shikimate kinase DUF2075 PF09848.4 EGC40114.1 - 0.0063 15.5 0.0 0.011 14.6 0.0 1.5 1 0 0 1 1 1 1 Uncharacterized conserved protein (DUF2075) ABC_tran PF00005.22 EGC40114.1 - 0.01 16.1 0.3 0.024 14.9 0.0 1.9 2 1 0 2 2 1 1 ABC transporter PduV-EutP PF10662.4 EGC40114.1 - 0.012 15.0 0.0 0.026 14.0 0.0 1.5 1 0 0 1 1 1 0 Ethanolamine utilisation - propanediol utilisation Parvo_NS1 PF01057.12 EGC40114.1 - 0.012 14.4 0.0 0.029 13.2 0.0 1.6 1 0 0 1 1 1 0 Parvovirus non-structural protein NS1 MMR_HSR1 PF01926.18 EGC40114.1 - 0.016 15.1 0.3 0.049 13.6 0.0 2.0 2 1 0 2 2 2 0 50S ribosome-binding GTPase AAA_30 PF13604.1 EGC40114.1 - 0.026 14.1 0.0 0.054 13.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain Sigma54_activat PF00158.21 EGC40114.1 - 0.064 12.7 0.0 0.12 11.8 0.0 1.5 1 0 0 1 1 1 0 Sigma-54 interaction domain KaiC PF06745.8 EGC40114.1 - 0.086 11.9 2.3 2.6 7.0 0.0 3.0 2 1 1 3 3 3 0 KaiC Miro PF08477.8 EGC40114.1 - 0.098 13.1 1.2 0.6 10.6 0.1 2.8 2 2 0 2 2 2 0 Miro-like protein DUF258 PF03193.11 EGC40114.1 - 0.1 11.7 0.0 0.23 10.6 0.0 1.7 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_23 PF13476.1 EGC40114.1 - 0.9 9.8 19.3 0.02 15.2 1.6 2.5 1 1 1 2 2 2 0 AAA domain zf-MYND PF01753.13 EGC40115.1 - 4e-08 32.9 12.0 7.9e-08 32.0 8.3 1.5 1 0 0 1 1 1 1 MYND finger DUF581 PF04570.9 EGC40115.1 - 1.8 7.9 8.2 0.32 10.3 2.9 1.9 2 0 0 2 2 2 0 Protein of unknown function (DUF581) AOX PF01786.12 EGC40116.1 - 1.4e-67 227.0 0.6 1.9e-67 226.6 0.5 1.1 1 0 0 1 1 1 1 Alternative oxidase AOX PF01786.12 EGC40117.1 - 7.6e-75 250.8 0.4 1e-74 250.4 0.3 1.1 1 0 0 1 1 1 1 Alternative oxidase DUF4020 PF13212.1 EGC40117.1 - 0.015 14.9 0.0 0.023 14.2 0.0 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4020) PTE PF02126.13 EGC40118.1 - 5.2e-84 281.8 0.1 6.7e-84 281.5 0.1 1.1 1 0 0 1 1 1 1 Phosphotriesterase family TatD_DNase PF01026.16 EGC40118.1 - 2.4e-05 23.6 0.0 3.6e-05 23.0 0.0 1.3 1 0 0 1 1 1 1 TatD related DNase Sec3_C_2 PF15278.1 EGC40118.1 - 0.094 12.8 0.0 6.1 7.0 0.0 3.2 3 0 0 3 3 3 0 Sec3 exocyst complex subunit Sybindin PF04099.7 EGC40119.1 - 8e-49 165.0 0.3 9e-49 164.8 0.2 1.0 1 0 0 1 1 1 1 Sybindin-like family Sedlin_N PF04628.8 EGC40119.1 - 8.6e-09 35.3 0.0 9.3e-09 35.2 0.0 1.1 1 0 0 1 1 1 1 Sedlin, N-terminal conserved region DUF3430 PF11912.3 EGC40120.1 - 1.1e-25 90.7 25.2 1.3e-25 90.4 17.5 1.0 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Sec62 PF03839.11 EGC40121.1 - 0.00016 21.1 2.6 0.00016 21.1 1.8 2.3 3 1 1 4 4 4 1 Translocation protein Sec62 CUE PF02845.11 EGC40122.1 - 1e-07 31.2 0.2 1e-07 31.2 0.1 2.1 2 0 0 2 2 2 1 CUE domain UBA_4 PF14555.1 EGC40122.1 - 0.026 14.0 0.1 0.089 12.3 0.1 1.9 1 0 0 1 1 1 0 UBA-like domain Presenilin PF01080.12 EGC40122.1 - 6.1 5.5 10.1 10 4.7 7.0 1.4 1 0 0 1 1 1 0 Presenilin SNARE PF05739.14 EGC40123.1 - 1.3e-06 28.0 2.6 1.6e-06 27.6 1.8 1.1 1 0 0 1 1 1 1 SNARE domain AMA-1 PF02430.10 EGC40123.1 - 0.07 11.9 0.1 0.071 11.9 0.1 1.1 1 0 0 1 1 1 0 Apical membrane antigen 1 Mid2 PF04478.7 EGC40123.1 - 0.086 12.2 1.5 0.14 11.5 1.0 1.4 1 0 0 1 1 1 0 Mid2 like cell wall stress sensor Peptidase_M50 PF02163.17 EGC40123.1 - 0.11 11.4 0.1 0.13 11.2 0.1 1.1 1 0 0 1 1 1 0 Peptidase family M50 Rifin_STEVOR PF02009.11 EGC40123.1 - 0.11 12.0 2.7 0.16 11.5 1.9 1.2 1 1 0 1 1 1 0 Rifin/stevor family Synaptobrevin PF00957.16 EGC40123.1 - 0.33 10.5 5.3 0.17 11.5 1.2 2.0 2 0 0 2 2 2 0 Synaptobrevin Npa1 PF11707.3 EGC40124.1 - 2.9e-54 184.2 8.8 2.9e-54 184.2 6.1 8.0 8 1 1 9 9 9 2 Ribosome 60S biogenesis N-terminal Esterase PF00756.15 EGC40125.1 - 7.7e-39 133.6 0.0 8.8e-39 133.4 0.0 1.0 1 0 0 1 1 1 1 Putative esterase Peptidase_S9 PF00326.16 EGC40125.1 - 0.00011 21.4 0.1 0.00014 21.1 0.1 1.2 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_2 PF02230.11 EGC40125.1 - 0.00033 20.1 0.0 0.00044 19.7 0.0 1.2 1 0 0 1 1 1 1 Phospholipase/Carboxylesterase PGAP1 PF07819.8 EGC40125.1 - 0.0021 17.6 0.1 0.0037 16.8 0.0 1.5 2 0 0 2 2 2 1 PGAP1-like protein Abhydrolase_5 PF12695.2 EGC40125.1 - 0.0058 16.3 0.0 0.0068 16.1 0.0 1.3 1 1 0 1 1 1 1 Alpha/beta hydrolase family Chlorophyllase2 PF12740.2 EGC40125.1 - 0.059 12.2 0.0 0.11 11.3 0.0 1.4 1 0 0 1 1 1 0 Chlorophyllase enzyme Lipase_3 PF01764.20 EGC40125.1 - 0.061 12.9 0.2 0.2 11.2 0.0 1.8 2 0 0 2 2 2 0 Lipase (class 3) MIT PF04212.13 EGC40127.1 - 5.5e-11 42.1 0.9 1.1e-10 41.1 0.6 1.6 1 0 0 1 1 1 1 MIT (microtubule interacting and transport) domain TPR_2 PF07719.12 EGC40127.1 - 0.027 14.3 0.9 0.18 11.8 0.1 2.5 2 0 0 2 2 2 0 Tetratricopeptide repeat ATP-synt_ab_C PF00306.22 EGC40127.1 - 0.049 14.1 0.8 0.92 10.0 0.5 2.4 1 1 0 1 1 1 0 ATP synthase alpha/beta chain, C terminal domain TPR_11 PF13414.1 EGC40127.1 - 0.059 13.0 1.0 0.16 11.6 0.7 1.8 1 1 0 1 1 1 0 TPR repeat PI3Ka PF00613.15 EGC40128.1 - 5.4e-61 205.0 1.2 1.2e-60 203.8 0.8 1.6 1 0 0 1 1 1 1 Phosphoinositide 3-kinase family, accessory domain (PIK domain) PI3_PI4_kinase PF00454.22 EGC40128.1 - 2e-46 158.3 0.0 4.4e-46 157.2 0.0 1.6 1 0 0 1 1 1 1 Phosphatidylinositol 3- and 4-kinase PI3K_C2 PF00792.19 EGC40128.1 - 9.3e-28 96.8 0.0 2.8e-27 95.2 0.0 1.9 1 0 0 1 1 1 1 Phosphoinositide 3-kinase C2 PI3K_rbd PF00794.13 EGC40128.1 - 2.1e-25 88.6 0.3 8.2e-23 80.3 0.0 3.7 2 1 1 3 3 3 2 PI3-kinase family, ras-binding domain Evr1_Alr PF04777.8 EGC40129.1 - 3e-05 23.8 0.1 0.00039 20.2 0.1 2.6 1 1 0 1 1 1 1 Erv1 / Alr family Pkinase PF00069.20 EGC40130.1 - 1.3e-69 234.2 0.0 1.5e-69 234.0 0.0 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40130.1 - 1.2e-31 109.7 0.1 1.7e-31 109.2 0.0 1.3 1 1 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC40130.1 - 1.1e-06 27.8 0.0 0.002 17.1 0.0 2.2 1 1 1 2 2 2 2 Kinase-like RIO1 PF01163.17 EGC40130.1 - 2e-05 24.0 0.3 3.1e-05 23.4 0.2 1.2 1 0 0 1 1 1 1 RIO1 family Rep_fac-A_C PF08646.5 EGC40130.1 - 0.049 13.3 0.1 0.077 12.6 0.1 1.3 1 0 0 1 1 1 0 Replication factor-A C terminal domain IF-2B PF01008.12 EGC40131.1 - 9.3e-75 251.2 0.0 1.1e-74 250.9 0.0 1.0 1 0 0 1 1 1 1 Initiation factor 2 subunit family DUF2963 PF11178.3 EGC40132.1 - 0.054 12.9 0.1 0.5 9.8 0.0 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF2963) FNIP PF05725.7 EGC40133.1 - 7.4e-90 294.7 39.3 1.5e-12 47.2 0.3 8.3 6 2 1 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 EGC40133.1 - 1.8e-07 30.9 22.1 4.1 7.4 0.0 10.0 4 3 7 11 11 11 5 Protein of unknown function (DUF1769) LRR_5 PF13306.1 EGC40133.1 - 1.6e-05 24.6 0.2 0.2 11.3 0.0 3.5 1 1 2 3 3 3 2 Leucine rich repeats (6 copies) Coiled PF05710.7 EGC40134.1 - 0.082 13.3 7.6 0.1 13.0 5.3 1.1 1 0 0 1 1 1 0 Coiled coil E1-E2_ATPase PF00122.15 EGC40136.1 - 3.5e-26 91.6 0.0 1e-25 90.1 0.0 1.8 1 0 0 1 1 1 1 E1-E2 ATPase Hydrolase PF00702.21 EGC40136.1 - 3.5e-15 56.9 0.0 2.5e-14 54.1 0.0 2.4 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase HAD PF12710.2 EGC40136.1 - 8.1e-14 52.2 0.0 2.3e-13 50.7 0.0 1.8 1 1 0 1 1 1 1 haloacid dehalogenase-like hydrolase Hydrolase_like2 PF13246.1 EGC40136.1 - 1.1e-11 44.4 0.0 3.6e-11 42.8 0.0 1.9 1 0 0 1 1 1 1 Putative hydrolase of sodium-potassium ATPase alpha subunit PseudoU_synth_1 PF01416.15 EGC40137.1 - 3.9e-31 107.5 0.0 4.6e-21 75.2 0.0 2.5 2 0 0 2 2 2 2 tRNA pseudouridine synthase Sod_Cu PF00080.15 EGC40138.1 - 7e-28 97.5 1.6 9.8e-24 84.1 1.8 2.6 2 1 0 2 2 2 2 Copper/zinc superoxide dismutase (SODC) AF-4 PF05110.8 EGC40138.1 - 4 5.1 10.1 5.1 4.8 7.0 1.1 1 0 0 1 1 1 0 AF-4 proto-oncoprotein DUF507 PF04368.8 EGC40139.1 - 0.0016 18.0 5.2 0.0021 17.7 3.6 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF507) DASH_Ask1 PF08655.5 EGC40139.1 - 0.0052 16.5 1.0 0.01 15.6 0.7 1.5 1 0 0 1 1 1 1 DASH complex subunit Ask1 V-ATPase_C PF03223.10 EGC40139.1 - 0.006 15.5 2.2 0.0074 15.2 1.5 1.2 1 0 0 1 1 1 1 V-ATPase subunit C Chalcone PF02431.10 EGC40139.1 - 0.0067 15.8 0.4 0.007 15.7 0.3 1.2 1 0 0 1 1 1 1 Chalcone-flavanone isomerase Orbi_NS3 PF01616.11 EGC40139.1 - 0.014 14.3 0.2 0.015 14.2 0.1 1.1 1 0 0 1 1 1 0 Orbivirus NS3 Syntaxin PF00804.20 EGC40139.1 - 0.017 15.2 5.1 0.025 14.7 3.6 1.3 1 0 0 1 1 1 0 Syntaxin DUF573 PF04504.9 EGC40139.1 - 0.026 14.8 4.6 0.63 10.3 0.4 2.3 1 1 1 2 2 2 0 Protein of unknown function, DUF573 ATP-synt_B PF00430.13 EGC40139.1 - 0.028 14.2 1.2 0.036 13.8 0.9 1.3 1 0 0 1 1 1 0 ATP synthase B/B' CF(0) DUF1845 PF08900.6 EGC40139.1 - 0.036 13.3 0.4 0.057 12.6 0.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF1845) AcylCoA_dehyd_C PF12186.3 EGC40139.1 - 0.038 13.8 1.0 0.48 10.3 0.1 2.0 1 1 1 2 2 2 0 Acyl-CoA dehydrogenase C terminal DUF1444 PF07285.6 EGC40139.1 - 0.046 13.0 2.8 0.045 13.0 1.9 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF1444) COG5 PF10392.4 EGC40139.1 - 0.078 12.9 0.1 0.13 12.2 0.1 1.3 1 0 0 1 1 1 0 Golgi transport complex subunit 5 DUF2278 PF10042.4 EGC40139.1 - 0.089 12.4 0.1 0.093 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterized conserved protein (DUF2278) SUKH_5 PF14567.1 EGC40139.1 - 0.12 11.8 5.5 0.69 9.3 2.5 2.0 1 1 1 2 2 2 0 SMI1-KNR4 cell-wall DUF1910 PF08928.5 EGC40139.1 - 0.14 12.1 4.8 0.19 11.7 3.3 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF1910) RPT PF13446.1 EGC40139.1 - 0.17 11.3 0.2 0.17 11.3 0.1 1.5 2 0 0 2 2 2 0 A repeated domain in UCH-protein DUF4014 PF13198.1 EGC40139.1 - 1.4 9.3 3.7 2.5 8.5 2.6 1.5 1 1 0 1 1 1 0 Protein of unknown function (DUF4014) TPR_MLP1_2 PF07926.7 EGC40139.1 - 1.4 8.6 9.0 0.52 10.0 4.3 1.8 2 1 0 2 2 2 0 TPR/MLP1/MLP2-like protein Malate_synthase PF01274.17 EGC40140.1 - 5.1e-88 295.3 0.0 1.2e-87 294.0 0.0 1.5 1 1 0 1 1 1 1 Malate synthase EGF_2 PF07974.8 EGC40141.1 - 0.046 13.8 10.4 0.087 13.0 7.2 1.4 1 0 0 1 1 1 0 EGF-like domain SKG6 PF08693.5 EGC40141.1 - 0.22 10.8 1.3 0.48 9.7 0.9 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain HAT PF02184.11 EGC40143.1 - 1.7e-21 75.6 55.9 1.3e-10 40.8 0.2 14.4 14 2 0 14 14 14 4 HAT (Half-A-TPR) repeat TPR_14 PF13428.1 EGC40143.1 - 2.6e-19 67.9 2.4 0.16 12.7 0.0 10.1 6 3 5 11 11 10 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGC40143.1 - 1e-18 67.4 0.0 0.015 15.9 0.0 7.9 5 1 3 9 9 9 2 Tetratricopeptide repeat TPR_19 PF14559.1 EGC40143.1 - 1.8e-15 57.0 0.6 0.12 12.6 0.0 6.8 5 1 3 8 8 8 4 Tetratricopeptide repeat Suf PF05843.9 EGC40143.1 - 3.3e-15 56.5 33.6 1.6e-05 24.8 1.4 8.0 1 1 5 7 7 7 5 Suppressor of forked protein (Suf) TPR_15 PF13429.1 EGC40143.1 - 5.3e-10 38.8 11.0 0.0039 16.2 0.0 4.6 2 2 2 4 4 4 3 Tetratricopeptide repeat TPR_12 PF13424.1 EGC40143.1 - 1.2e-08 34.7 9.6 0.033 14.1 0.2 6.4 3 3 2 5 5 5 3 Tetratricopeptide repeat TPR_8 PF13181.1 EGC40143.1 - 2e-08 33.4 12.0 0.011 15.3 0.1 8.2 7 1 1 8 8 8 1 Tetratricopeptide repeat TPR_11 PF13414.1 EGC40143.1 - 2.9e-08 33.2 7.6 0.77 9.4 0.0 6.3 6 0 0 6 6 6 2 TPR repeat TPR_6 PF13174.1 EGC40143.1 - 3e-07 30.4 12.0 17 6.1 0.1 9.0 10 0 0 10 10 9 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC40143.1 - 3.1e-06 26.6 21.3 6.9 6.8 0.0 9.5 12 0 0 12 12 9 2 Tetratricopeptide repeat TPR_7 PF13176.1 EGC40143.1 - 6.5e-06 25.5 5.2 4 7.4 0.1 7.2 7 0 0 7 7 7 1 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGC40143.1 - 0.00023 20.9 27.0 0.35 10.6 1.3 6.4 5 1 1 7 7 7 3 Mad3/BUB1 homology region 1 TPR_17 PF13431.1 EGC40143.1 - 0.00028 20.8 0.3 0.56 10.5 0.0 3.9 2 0 0 2 2 2 1 Tetratricopeptide repeat DNA_pol3_tau_4 PF12168.3 EGC40143.1 - 0.013 15.9 2.1 0.013 15.9 1.5 1.9 2 0 0 2 2 1 0 DNA polymerase III subunits tau domain IV DnaB-binding Apc3 PF12895.2 EGC40143.1 - 0.019 15.0 3.0 1.2 9.3 0.0 4.3 5 0 0 5 5 5 0 Anaphase-promoting complex, cyclosome, subunit 3 U3_assoc_6 PF08640.6 EGC40143.1 - 0.025 14.3 0.2 0.025 14.3 0.2 7.8 5 3 4 9 9 9 0 U3 small nucleolar RNA-associated protein 6 TPPII_N PF12583.3 EGC40143.1 - 0.084 13.0 0.3 16 5.6 0.0 3.3 3 1 1 4 4 3 0 Tripeptidyl peptidase II N terminal TPR_1 PF00515.23 EGC40143.1 - 0.27 10.9 4.7 33 4.2 0.0 5.1 6 0 0 6 6 5 0 Tetratricopeptide repeat Glycos_transf_2 PF00535.21 EGC40144.1 - 1.9e-18 66.7 0.0 1.3e-09 37.9 0.0 3.0 2 0 0 2 2 2 2 Glycosyl transferase family 2 Glyco_tranf_2_3 PF13641.1 EGC40144.1 - 0.0058 16.4 0.0 0.046 13.5 0.0 2.0 1 1 0 1 1 1 1 Glycosyltransferase like family 2 ETRAMP PF09716.5 EGC40145.1 - 0.0069 16.3 4.8 0.0069 16.3 3.3 2.6 2 1 0 2 2 2 1 Malarial early transcribed membrane protein (ETRAMP) DUF912 PF06024.7 EGC40145.1 - 0.0093 16.0 3.6 0.0093 16.0 2.5 2.0 2 0 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Sigma_reg_N PF13800.1 EGC40145.1 - 0.018 15.0 4.6 0.018 15.0 3.2 2.1 2 0 0 2 2 2 0 Sigma factor regulator N-terminal CD34_antigen PF06365.7 EGC40145.1 - 0.029 14.0 0.9 0.051 13.2 0.7 1.3 1 0 0 1 1 1 0 CD34/Podocalyxin family ATP-synt_8 PF00895.15 EGC40145.1 - 0.049 13.8 2.4 0.049 13.8 1.6 3.7 3 1 1 4 4 4 0 ATP synthase protein 8 DUF3139 PF11337.3 EGC40145.1 - 0.75 10.1 7.2 0.53 10.5 3.0 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF3139) ODV-E18 PF10717.4 EGC40145.1 - 1 8.8 6.3 0.21 11.0 1.6 2.0 2 0 0 2 2 2 0 Occlusion-derived virus envelope protein ODV-E18 Miff PF05644.6 EGC40146.1 - 0.12 11.9 6.9 0.17 11.4 4.8 1.2 1 0 0 1 1 1 0 Mitochondrial and peroxisomal fission factor Mff Macoilin PF09726.4 EGC40146.1 - 3.6 5.7 24.6 4.6 5.3 17.1 1.1 1 0 0 1 1 1 0 Transmembrane protein Coagulin PF02035.10 EGC40147.1 - 0.031 13.9 0.3 0.048 13.3 0.1 1.3 1 1 0 1 1 1 0 Coagulin Pho88 PF10032.4 EGC40148.1 - 0.12 11.5 0.0 0.16 11.1 0.0 1.2 1 0 0 1 1 1 0 Phosphate transport (Pho88) CBM49 PF09478.5 EGC40149.1 - 4.4e-15 55.5 3.6 5.8e-15 55.1 2.5 1.1 1 0 0 1 1 1 1 Carbohydrate binding domain CBM49 CBM49 PF09478.5 EGC40150.1 - 2.8e-09 36.9 0.5 5.1e-09 36.0 0.3 1.5 1 1 0 1 1 1 1 Carbohydrate binding domain CBM49 eIF-3c_N PF05470.7 EGC40151.1 - 8.6e-132 440.2 21.8 8.6e-132 440.2 15.1 2.1 2 0 0 2 2 2 1 Eukaryotic translation initiation factor 3 subunit 8 N-terminus PCI PF01399.22 EGC40151.1 - 4.3e-12 46.2 0.2 4.3e-11 43.0 0.1 2.6 2 0 0 2 2 2 1 PCI domain MarR_2 PF12802.2 EGC40151.1 - 0.14 11.8 0.0 0.36 10.5 0.0 1.6 1 0 0 1 1 1 0 MarR family Zip PF02535.17 EGC40151.1 - 8.5 5.2 20.8 1.8 7.4 7.2 2.6 2 0 0 2 2 2 0 ZIP Zinc transporter tRNA-synt_1g PF09334.6 EGC40152.1 - 1.4e-134 448.6 2.8 4.5e-134 446.9 1.9 1.8 1 1 0 1 1 1 1 tRNA synthetases class I (M) tRNA_bind PF01588.15 EGC40152.1 - 1.4e-21 76.1 0.2 2.2e-21 75.4 0.1 1.4 1 0 0 1 1 1 1 Putative tRNA binding domain tRNA-synt_1 PF00133.17 EGC40152.1 - 2.4e-09 35.7 1.3 9.9e-05 20.5 0.0 2.6 2 1 1 3 3 3 2 tRNA synthetases class I (I, L, M and V) Anticodon_1 PF08264.8 EGC40152.1 - 7.7e-07 28.9 0.3 1.7e-06 27.8 0.0 1.7 2 0 0 2 2 2 1 Anticodon-binding domain of tRNA DZR PF12773.2 EGC40152.1 - 4.1 7.2 7.7 9.5 6.1 5.3 1.6 1 0 0 1 1 1 0 Double zinc ribbon His_Phos_1 PF00300.17 EGC40153.1 - 1.7e-30 106.1 0.2 2.9e-30 105.4 0.1 1.4 1 0 0 1 1 1 1 Histidine phosphatase superfamily (branch 1) BssC_TutF PF08201.6 EGC40153.1 - 0.02 14.3 0.1 0.047 13.1 0.1 1.6 1 0 0 1 1 1 0 BssC/TutF protein Phage_Gp111 PF07410.6 EGC40154.1 - 0.081 13.0 0.3 0.2 11.8 0.2 1.6 1 0 0 1 1 1 0 Streptococcus thermophilus bacteriophage Gp111 protein SR-25 PF10500.4 EGC40154.1 - 7.7 5.9 10.5 14 5.0 7.2 1.4 1 0 0 1 1 1 0 Nuclear RNA-splicing-associated protein HisG PF01634.13 EGC40155.1 - 0.075 12.6 0.0 0.13 11.7 0.0 1.4 1 1 0 1 1 1 0 ATP phosphoribosyltransferase DUF4448 PF14610.1 EGC40155.1 - 2.7 7.4 4.6 1.6 8.1 1.2 1.8 2 1 0 2 2 2 0 Protein of unknown function (DUF4448) Mac PF12464.3 EGC40156.1 - 1.8e-17 63.0 0.1 2.6e-17 62.5 0.0 1.2 1 0 0 1 1 1 1 Maltose acetyltransferase Hexapep PF00132.19 EGC40156.1 - 2.9e-12 45.5 12.8 3.1e-10 39.0 4.0 3.5 3 1 0 3 3 3 2 Bacterial transferase hexapeptide (six repeats) Hexapep_2 PF14602.1 EGC40156.1 - 1.8e-11 43.4 16.7 4.4e-10 38.9 4.2 3.3 4 0 0 4 4 4 2 Hexapeptide repeat of succinyl-transferase COesterase PF00135.23 EGC40157.1 - 9.3e-119 397.5 0.0 1e-118 397.3 0.0 1.0 1 0 0 1 1 1 1 Carboxylesterase family Abhydrolase_3 PF07859.8 EGC40157.1 - 2.1e-06 27.4 0.0 4.2e-06 26.4 0.0 1.5 1 1 0 1 1 1 1 alpha/beta hydrolase fold DUF192 PF02643.10 EGC40157.1 - 0.064 12.9 0.0 0.11 12.1 0.0 1.3 1 0 0 1 1 1 0 Uncharacterized ACR, COG1430 Abhydrolase_5 PF12695.2 EGC40157.1 - 0.067 12.9 0.0 0.14 11.9 0.0 1.6 1 1 0 1 1 1 0 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC40157.1 - 0.074 12.2 0.1 0.14 11.4 0.1 1.4 1 0 0 1 1 1 0 Prolyl oligopeptidase family DUF4010 PF13194.1 EGC40158.1 - 0.017 14.4 2.8 0.03 13.6 2.0 1.4 1 1 0 1 1 1 0 Domain of unknown function (DUF4010) MCM PF00493.18 EGC40160.1 - 2.2e-124 414.5 0.6 4.2e-123 410.3 0.0 2.1 2 0 0 2 2 2 1 MCM2/3/5 family Mg_chelatase PF01078.16 EGC40160.1 - 6e-10 38.6 0.1 9.3e-08 31.4 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_5 PF07728.9 EGC40160.1 - 8.6e-09 35.2 0.0 2e-08 34.0 0.0 1.7 1 0 0 1 1 1 1 AAA domain (dynein-related subfamily) AAA_3 PF07726.6 EGC40160.1 - 6.7e-05 22.5 0.0 0.00024 20.7 0.0 1.9 1 1 0 1 1 1 1 ATPase family associated with various cellular activities (AAA) MCM_N PF14551.1 EGC40160.1 - 8.8e-05 22.9 3.8 0.00013 22.4 1.2 2.3 2 0 0 2 2 2 1 MCM N-terminal domain Sigma54_activat PF00158.21 EGC40160.1 - 0.00034 20.1 0.0 0.0011 18.4 0.0 1.8 1 1 0 1 1 1 1 Sigma-54 interaction domain cobW PF02492.14 EGC40160.1 - 0.053 12.9 0.0 0.11 11.8 0.0 1.6 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain FtsK_SpoIIIE PF01580.13 EGC40160.1 - 0.054 12.9 0.0 0.1 12.0 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_22 PF13401.1 EGC40160.1 - 0.079 13.1 0.0 0.32 11.1 0.0 2.0 1 0 0 1 1 1 0 AAA domain APG12 PF04110.8 EGC40161.1 - 6.3e-28 96.7 0.2 8.3e-28 96.4 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin-like autophagy protein Apg12 Atg8 PF02991.11 EGC40161.1 - 5e-07 29.6 0.0 6e-07 29.3 0.0 1.1 1 0 0 1 1 1 1 Autophagy protein Atg8 ubiquitin like Spond_N PF06468.8 EGC40161.1 - 0.032 13.9 0.1 0.086 12.5 0.0 1.5 1 1 1 2 2 2 0 Spondin_N Pkinase_Tyr PF07714.12 EGC40162.1 - 1.8e-60 204.2 0.0 2.4e-60 203.8 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC40162.1 - 2.8e-47 161.0 0.0 3.9e-47 160.5 0.0 1.2 1 0 0 1 1 1 1 Protein kinase domain SH2 PF00017.19 EGC40162.1 - 4.8e-16 58.3 0.1 9.6e-16 57.3 0.1 1.5 1 0 0 1 1 1 1 SH2 domain APH PF01636.18 EGC40162.1 - 0.00065 19.4 0.0 0.0016 18.1 0.0 1.6 1 0 0 1 1 1 1 Phosphotransferase enzyme family ABC1 PF03109.11 EGC40162.1 - 0.11 12.4 0.0 0.24 11.3 0.0 1.5 1 0 0 1 1 1 0 ABC1 family Pkinase PF00069.20 EGC40163.1 - 5.1e-54 183.1 0.0 8.8e-54 182.3 0.0 1.4 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40163.1 - 1.7e-35 122.3 0.0 2.7e-35 121.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC40163.1 - 5.7e-05 22.2 0.0 0.00014 20.9 0.0 1.6 1 1 0 1 1 1 1 Kinase-like Rad50_zn_hook PF04423.9 EGC40163.1 - 0.0048 16.3 0.9 0.013 14.9 0.6 1.7 1 0 0 1 1 1 1 Rad50 zinc hook motif Kdo PF06293.9 EGC40163.1 - 0.037 13.1 0.0 0.067 12.2 0.0 1.3 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TIG PF01833.19 EGC40164.1 - 2.2 8.3 12.5 0.16 11.9 2.0 3.5 3 0 0 3 3 3 0 IPT/TIG domain zf-DHHC PF01529.15 EGC40165.1 - 2e-34 118.4 8.9 2e-34 118.4 6.2 3.7 2 1 1 3 3 2 1 DHHC palmitoyltransferase DUF1510 PF07423.6 EGC40165.1 - 4.9e-05 22.7 5.2 0.00012 21.5 3.6 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF1510) Peptidase_S49_N PF08496.5 EGC40165.1 - 0.00035 20.3 3.9 0.0008 19.2 2.7 1.5 1 0 0 1 1 1 1 Peptidase family S49 N-terminal Ni_hydr_CYTB PF01292.15 EGC40165.1 - 0.0013 18.2 0.1 0.0013 18.2 0.1 2.2 2 1 0 2 2 2 1 Prokaryotic cytochrome b561 IncA PF04156.9 EGC40165.1 - 0.0045 16.5 0.2 0.0045 16.5 0.1 1.7 2 0 0 2 2 2 1 IncA protein PIG-P PF08510.7 EGC40165.1 - 0.0046 16.5 0.0 0.0046 16.5 0.0 3.6 4 0 0 4 4 4 1 PIG-P DUF4199 PF13858.1 EGC40165.1 - 0.14 12.0 9.8 2.2 8.1 0.0 4.1 4 0 0 4 4 4 0 Protein of unknown function (DUF4199) DUF2215 PF10225.4 EGC40165.1 - 0.3 10.4 4.7 0.051 13.0 0.4 1.7 2 0 0 2 2 2 0 Uncharacterized conserved protein (DUF2215) Reticulon PF02453.12 EGC40165.1 - 0.35 10.4 0.0 0.35 10.4 0.0 3.0 3 0 0 3 3 3 0 Reticulon DUF3573 PF12097.3 EGC40165.1 - 0.39 9.2 3.7 0.57 8.7 2.6 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3573) DUF2244 PF10003.4 EGC40165.1 - 0.4 10.0 0.0 0.4 10.0 0.0 2.5 3 0 0 3 3 2 0 Integral membrane protein (DUF2244) CPSF100_C PF13299.1 EGC40165.1 - 0.57 10.3 9.8 0.82 9.8 6.8 1.1 1 0 0 1 1 1 0 Cleavage and polyadenylation factor 2 C-terminal DUF788 PF05620.6 EGC40165.1 - 1.2 8.9 4.9 3.9 7.3 0.1 3.0 2 1 0 2 2 2 0 Protein of unknown function (DUF788) Cytochrom_B_N PF00033.14 EGC40165.1 - 1.7 8.0 0.0 1.7 8.0 0.0 3.2 3 1 0 3 3 3 0 Cytochrome b(N-terminal)/b6/petB CDC45 PF02724.9 EGC40165.1 - 2.3 6.1 8.7 3 5.7 6.1 1.1 1 0 0 1 1 1 0 CDC45-like protein Neur_chan_memb PF02932.11 EGC40165.1 - 3.3 7.5 6.9 0.16 11.8 0.1 2.1 3 0 0 3 3 3 0 Neurotransmitter-gated ion-channel transmembrane region DUF4131 PF13567.1 EGC40165.1 - 3.9 6.8 8.4 1.1 8.6 0.7 3.1 2 1 0 2 2 2 0 Domain of unknown function (DUF4131) Evr1_Alr PF04777.8 EGC40166.1 - 2.1e-05 24.3 1.3 2.1e-05 24.3 0.9 3.0 2 2 1 3 3 3 1 Erv1 / Alr family EGF_2 PF07974.8 EGC40167.1 - 0.02 15.0 14.1 0.058 13.5 9.7 1.9 1 0 0 1 1 1 0 EGF-like domain FNIP PF05725.7 EGC40168.1 - 4.4e-49 164.1 58.6 2.3e-05 24.2 1.5 12.7 10 3 2 13 13 13 11 FNIP Repeat Glyco_hydro_114 PF03537.8 EGC40168.1 - 0.0059 16.3 1.9 58 3.5 0.0 6.1 3 2 4 7 7 7 0 Glycoside-hydrolase family GH114 AAA_3 PF07726.6 EGC40168.1 - 0.0094 15.5 1.6 35 3.9 0.0 5.1 2 2 5 7 7 7 0 ATPase family associated with various cellular activities (AAA) zf-B_box PF00643.19 EGC40168.1 - 0.08 12.8 11.8 0.13 12.1 8.2 1.3 1 0 0 1 1 1 0 B-box zinc finger Tubulin-binding PF00418.14 EGC40168.1 - 2.7 7.7 9.2 79 3.0 0.0 6.5 8 0 0 8 8 8 0 Tau and MAP protein, tubulin-binding repeat Suf PF05843.9 EGC40169.1 - 5.3e-12 46.0 42.5 5.5e-08 32.8 4.1 5.0 1 1 2 4 4 4 4 Suppressor of forked protein (Suf) TPR_16 PF13432.1 EGC40169.1 - 0.0019 18.8 0.0 0.0076 16.8 0.0 2.0 2 0 0 2 2 2 1 Tetratricopeptide repeat MCP_N PF05581.7 EGC40169.1 - 0.0049 17.0 0.0 0.093 12.8 0.0 2.6 2 0 0 2 2 2 1 Vibrio chemotaxis protein N terminus TPR_11 PF13414.1 EGC40169.1 - 0.005 16.4 0.3 0.086 12.5 0.1 2.9 4 0 0 4 4 4 1 TPR repeat TPR_19 PF14559.1 EGC40169.1 - 0.0051 17.1 0.0 4.7 7.6 0.0 3.8 4 0 0 4 4 4 1 Tetratricopeptide repeat TPR_15 PF13429.1 EGC40169.1 - 0.019 14.0 0.1 0.31 10.0 0.0 2.4 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_6 PF13174.1 EGC40169.1 - 0.028 14.8 1.1 1e+02 3.7 0.0 5.2 6 0 0 6 6 6 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC40169.1 - 0.055 14.1 0.0 2.9 8.7 0.0 3.7 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_2 PF07719.12 EGC40169.1 - 0.091 12.7 0.4 2.2 8.3 0.1 3.2 4 0 0 4 4 4 0 Tetratricopeptide repeat Mad3_BUB1_I PF08311.7 EGC40169.1 - 1.8 8.3 18.6 2.8 7.7 1.6 5.8 4 2 1 5 5 5 0 Mad3/BUB1 homology region 1 Peptidase_S9 PF00326.16 EGC40170.1 - 1.1e-09 37.8 0.0 1.9e-09 37.0 0.0 1.3 1 0 0 1 1 1 1 Prolyl oligopeptidase family Abhydrolase_5 PF12695.2 EGC40170.1 - 9.3e-07 28.7 0.0 1.9e-06 27.7 0.0 1.4 1 0 0 1 1 1 1 Alpha/beta hydrolase family Esterase PF00756.15 EGC40170.1 - 0.00029 20.3 0.0 0.00062 19.2 0.0 1.5 1 0 0 1 1 1 1 Putative esterase DUF915 PF06028.6 EGC40170.1 - 0.0093 15.0 0.0 0.025 13.6 0.0 1.6 1 0 0 1 1 1 1 Alpha/beta hydrolase of unknown function (DUF915) Acyl-CoA_dh_1 PF00441.19 EGC40171.1 - 5.7e-46 156.3 0.2 8.5e-46 155.7 0.2 1.3 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_N PF02771.11 EGC40171.1 - 6.5e-28 97.5 0.0 1.6e-27 96.2 0.0 1.7 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, N-terminal domain Acyl-CoA_dh_2 PF08028.6 EGC40171.1 - 1.4e-21 77.1 0.0 2e-21 76.6 0.0 1.2 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, C-terminal domain Acyl-CoA_dh_M PF02770.14 EGC40171.1 - 7.1e-19 67.0 0.1 1.2e-18 66.3 0.0 1.4 1 0 0 1 1 1 1 Acyl-CoA dehydrogenase, middle domain DUF3439 PF11921.3 EGC40172.1 - 0.44 10.2 16.6 0.041 13.6 6.5 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3439) DUF853 PF05872.7 EGC40172.1 - 0.46 8.7 5.9 0.91 7.8 4.1 1.5 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) PRESAN PF09687.5 EGC40173.1 - 0.66 10.0 5.4 1.6 8.8 3.8 1.5 1 1 0 1 1 1 0 Plasmodium RESA N-terminal DUF221 PF02714.10 EGC40174.1 - 2.4e-86 289.5 21.0 2.4e-86 289.5 14.6 2.1 3 0 0 3 3 3 1 Domain of unknown function DUF221 RSN1_TM PF13967.1 EGC40174.1 - 1.6e-34 118.7 5.0 1.6e-34 118.7 3.5 3.1 4 0 0 4 4 4 1 Late exocytosis, associated with Golgi transport DUF4463 PF14703.1 EGC40174.1 - 4.4e-08 33.5 0.0 7.7e-08 32.7 0.0 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF4463) AIRC PF00731.15 EGC40175.1 - 4.4e-64 214.2 1.1 7.8e-64 213.4 0.8 1.4 1 0 0 1 1 1 1 AIR carboxylase SAICAR_synt PF01259.13 EGC40175.1 - 1.2e-59 201.4 2.5 1.4e-59 201.2 0.1 2.3 3 1 1 4 4 4 1 SAICAR synthetase ATP-grasp PF02222.17 EGC40175.1 - 6.6e-54 181.8 0.1 1.7e-53 180.5 0.0 1.7 2 0 0 2 2 2 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGC40175.1 - 7.6e-13 48.5 0.0 4.2e-12 46.1 0.0 2.0 2 0 0 2 2 2 1 ATP-grasp domain ATPgrasp_Ter PF15632.1 EGC40175.1 - 1.1e-06 27.6 0.0 1.9e-06 26.8 0.0 1.3 1 0 0 1 1 1 1 ATP-grasp in the biosynthetic pathway with Ter operon GARS_A PF01071.14 EGC40175.1 - 6.2e-06 25.9 0.1 1.3e-05 24.8 0.1 1.5 1 0 0 1 1 1 1 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain CPSase_L_D2 PF02786.12 EGC40175.1 - 1.7e-05 24.2 0.0 3.5e-05 23.1 0.0 1.5 1 0 0 1 1 1 1 Carbamoyl-phosphate synthase L chain, ATP binding domain Dala_Dala_lig_C PF07478.8 EGC40175.1 - 0.014 14.7 0.1 0.12 11.7 0.1 2.5 1 1 0 1 1 1 0 D-ala D-ala ligase C-terminus 2-Hacid_dh_C PF02826.14 EGC40175.1 - 0.1 11.7 0.0 0.23 10.5 0.0 1.5 1 0 0 1 1 1 0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain IBR PF01485.16 EGC40176.1 - 1.3e-16 60.2 10.5 2.5e-14 52.8 3.5 2.1 2 0 0 2 2 2 2 IBR domain zf-piccolo PF05715.8 EGC40176.1 - 0.64 10.0 4.1 4.2 7.4 0.0 2.3 2 0 0 2 2 2 0 Piccolo Zn-finger DZR PF12773.2 EGC40176.1 - 1 9.2 11.4 1.1e+02 2.7 3.1 2.7 1 1 1 2 2 2 0 Double zinc ribbon C1_4 PF07975.7 EGC40176.1 - 1.1 9.3 15.9 0.3 11.1 5.7 2.4 1 1 1 2 2 2 0 TFIIH C1-like domain DUF3039 PF11238.3 EGC40176.1 - 1.5 8.2 6.0 4.9 6.6 1.1 2.4 2 0 0 2 2 2 0 Protein of unknown function (DUF3039) zf-C3HC4_2 PF13923.1 EGC40176.1 - 1.6 8.8 8.3 2.1 8.4 0.7 2.6 3 0 0 3 3 3 0 Zinc finger, C3HC4 type (RING finger) zf-AN1 PF01428.11 EGC40176.1 - 6.7 6.6 10.6 3.7 7.4 3.8 2.5 2 1 0 2 2 2 0 AN1-like Zinc finger Sec1 PF00995.18 EGC40177.1 - 8e-132 440.7 8.0 9e-132 440.5 5.6 1.0 1 0 0 1 1 1 1 Sec1 family NADH_dh_m_C1 PF15088.1 EGC40177.1 - 0.05 13.1 0.1 0.1 12.0 0.0 1.5 1 0 0 1 1 1 0 NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial adh_short PF00106.20 EGC40178.1 - 0.0025 17.7 0.0 0.0039 17.1 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short PF00106.20 EGC40179.1 - 0.00049 20.0 0.0 0.00076 19.4 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Cript PF10235.4 EGC40179.1 - 0.021 15.1 1.7 0.021 15.1 1.1 3.2 4 0 0 4 4 4 0 Microtubule-associated protein CRIPT KR PF08659.5 EGC40179.1 - 0.35 10.5 0.0 0.55 9.8 0.0 1.2 1 0 0 1 1 1 0 KR domain E1_dh PF00676.15 EGC40180.1 - 1.9e-108 361.7 0.3 2.2e-108 361.4 0.2 1.1 1 0 0 1 1 1 1 Dehydrogenase E1 component TPP_enzyme_C PF02775.16 EGC40180.1 - 3.2e-05 23.5 1.2 6e-05 22.6 0.8 1.5 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain DXP_synthase_N PF13292.1 EGC40180.1 - 0.00061 18.7 0.0 0.0011 17.9 0.0 1.4 1 0 0 1 1 1 1 1-deoxy-D-xylulose-5-phosphate synthase Pkinase PF00069.20 EGC40181.1 - 1e-45 155.9 0.0 2.3e-45 154.7 0.0 1.6 1 0 0 1 1 1 1 Protein kinase domain RhoGEF PF00621.15 EGC40181.1 - 3.8e-37 127.8 1.5 1.2e-36 126.3 1.0 1.9 1 0 0 1 1 1 1 RhoGEF domain Pkinase_Tyr PF07714.12 EGC40181.1 - 3.8e-37 127.7 0.0 6.7e-37 126.9 0.0 1.4 1 0 0 1 1 1 1 Protein tyrosine kinase PH PF00169.24 EGC40181.1 - 3.6e-08 33.5 0.2 2.1e-07 31.0 0.0 2.5 2 0 0 2 2 2 1 PH domain APH PF01636.18 EGC40181.1 - 0.00039 20.2 0.0 0.13 11.9 0.0 2.3 1 1 1 2 2 2 2 Phosphotransferase enzyme family Cortex-I_coil PF09304.5 EGC40181.1 - 0.86 9.6 5.1 1.6 8.7 0.1 2.7 2 0 0 2 2 2 0 Cortexillin I, coiled coil ETRAMP PF09716.5 EGC40182.1 - 0.1 12.5 1.0 0.21 11.5 0.5 1.8 1 1 1 2 2 2 0 Malarial early transcribed membrane protein (ETRAMP) Baculo_p74_N PF08404.5 EGC40182.1 - 0.12 11.1 2.0 0.37 9.5 0.1 2.1 2 1 1 3 3 3 0 Baculoviridae P74 N-terminal TIG PF01833.19 EGC40183.1 - 0.00012 21.9 51.7 0.0002 21.3 1.5 7.8 7 1 1 8 8 8 3 IPT/TIG domain YL1_C PF08265.6 EGC40184.1 - 0.044 13.3 0.1 0.078 12.5 0.0 1.4 1 0 0 1 1 1 0 YL1 nuclear protein C-terminal domain TIG PF01833.19 EGC40185.1 - 2.6e-07 30.5 48.1 3.4e-05 23.7 2.2 7.1 8 1 0 8 8 8 3 IPT/TIG domain ubiquitin PF00240.18 EGC40186.1 - 1e-17 63.2 2.8 2.2e-17 62.1 0.6 2.1 2 0 0 2 2 2 1 Ubiquitin family Rad60-SLD PF11976.3 EGC40186.1 - 1e-11 44.3 0.6 1.9e-11 43.5 0.4 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like DUF3990 PF13151.1 EGC40186.1 - 0.0036 16.6 0.0 0.0084 15.4 0.0 1.6 1 0 0 1 1 1 1 Protein of unknown function (DUF3990) PARP PF00644.15 EGC40186.1 - 0.016 14.6 0.0 0.026 13.9 0.0 1.3 1 0 0 1 1 1 0 Poly(ADP-ribose) polymerase catalytic domain TIG PF01833.19 EGC40187.1 - 0.0007 19.5 3.0 0.0007 19.5 2.0 2.5 1 1 1 3 3 3 1 IPT/TIG domain DUF4179 PF13786.1 EGC40187.1 - 0.064 13.4 1.1 0.19 11.9 0.8 1.9 1 0 0 1 1 1 0 Domain of unknown function (DUF4179) TIG PF01833.19 EGC40189.1 - 0.0027 17.6 2.1 0.0027 17.6 1.5 8.0 6 4 2 9 9 9 4 IPT/TIG domain TIG PF01833.19 EGC40190.1 - 2.2e-05 24.3 57.2 0.00012 22.0 1.6 7.6 8 2 0 8 8 8 5 IPT/TIG domain TIG PF01833.19 EGC40191.1 - 2.4e-05 24.2 51.2 0.00023 21.1 2.2 7.9 7 2 1 8 8 8 4 IPT/TIG domain DNA_pol_E_B PF04042.11 EGC40192.1 - 3.7e-30 104.7 5.8 6.7e-30 103.8 4.0 1.4 1 0 0 1 1 1 1 DNA polymerase alpha/epsilon subunit B eIF-3c_N PF05470.7 EGC40192.1 - 0.18 9.8 6.4 0.28 9.2 4.4 1.2 1 0 0 1 1 1 0 Eukaryotic translation initiation factor 3 subunit 8 N-terminus bZIP_C PF12498.3 EGC40192.1 - 1.7 9.9 7.9 0.71 11.1 2.1 2.7 3 0 0 3 3 3 0 Basic leucine-zipper C terminal Complex1_LYR PF05347.10 EGC40193.1 - 1.1e-08 34.7 0.3 1.7e-08 34.1 0.2 1.3 1 0 0 1 1 1 1 Complex 1 protein (LYR family) Complex1_LYR_1 PF13232.1 EGC40193.1 - 2.1e-07 31.0 0.3 3e-07 30.5 0.2 1.2 1 0 0 1 1 1 1 Complex1_LYR-like BNR PF02012.15 EGC40195.1 - 0.37 10.7 8.6 0.59 10.1 0.7 4.0 3 0 0 3 3 3 0 BNR/Asp-box repeat UPF0220 PF05255.6 EGC40196.1 - 3.1e-42 143.6 1.3 3.4e-42 143.5 0.9 1.0 1 0 0 1 1 1 1 Uncharacterised protein family (UPF0220) DUF4199 PF13858.1 EGC40196.1 - 0.0034 17.3 0.3 0.051 13.4 0.1 2.2 2 0 0 2 2 2 1 Protein of unknown function (DUF4199) DUF3112 PF11309.3 EGC40196.1 - 0.043 13.6 1.3 0.062 13.0 0.9 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3112) DUF805 PF05656.9 EGC40196.1 - 1.2 8.9 6.8 2.7 7.8 2.3 2.4 2 1 1 3 3 3 0 Protein of unknown function (DUF805) Dicty_CTDC PF00526.13 EGC40197.1 - 0.00047 19.9 4.8 0.00047 19.9 3.3 5.3 5 1 0 5 5 5 2 Dictyostelium (slime mold) repeat IF4E PF01652.13 EGC40198.1 - 2.4e-39 134.5 0.2 3.2e-39 134.1 0.1 1.1 1 0 0 1 1 1 1 Eukaryotic initiation factor 4E TIG PF01833.19 EGC40199.1 - 0.00018 21.4 4.9 0.002 18.0 1.0 2.4 2 0 0 2 2 2 2 IPT/TIG domain TIG PF01833.19 EGC40200.1 - 1.2e-23 82.8 36.6 0.0002 21.2 0.1 7.7 6 2 2 8 8 8 6 IPT/TIG domain RHD3 PF05879.7 EGC40202.1 - 6.4e-183 609.6 19.7 1e-182 608.9 13.7 1.3 1 0 0 1 1 1 1 Root hair defective 3 GTP-binding protein (RHD3) MMR_HSR1 PF01926.18 EGC40202.1 - 9.2e-05 22.3 0.5 0.0004 20.3 0.0 2.4 2 0 0 2 2 2 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC40202.1 - 0.0021 17.9 0.0 0.0021 17.9 0.0 3.7 4 1 0 4 4 4 1 Dynamin family Miro PF08477.8 EGC40202.1 - 0.023 15.1 0.0 0.086 13.3 0.0 2.1 1 0 0 1 1 1 0 Miro-like protein AAA_28 PF13521.1 EGC40202.1 - 0.051 13.5 1.1 0.13 12.2 0.0 2.2 3 0 0 3 3 3 0 AAA domain Transpos_assoc PF13963.1 EGC40202.1 - 0.11 12.4 0.9 0.4 10.7 0.1 2.4 2 0 0 2 2 2 0 Transposase-associated domain ABC_tran PF00005.22 EGC40202.1 - 0.62 10.3 0.0 0.62 10.3 0.0 4.1 4 0 0 4 4 4 0 ABC transporter Ank_2 PF12796.2 EGC40203.1 - 2.1e-41 140.1 15.4 1.6e-12 47.5 0.5 5.2 2 2 3 5 5 5 5 Ankyrin repeats (3 copies) SIR2 PF02146.12 EGC40203.1 - 1.1e-39 136.0 0.0 3e-39 134.5 0.0 1.8 1 0 0 1 1 1 1 Sir2 family Ank PF00023.25 EGC40203.1 - 1.1e-38 129.1 14.7 0.00013 21.6 0.0 9.4 9 0 0 9 9 9 8 Ankyrin repeat Ank_5 PF13857.1 EGC40203.1 - 4.3e-30 103.0 13.7 6.5e-08 32.5 0.6 6.8 3 2 3 6 6 6 6 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC40203.1 - 1.9e-29 101.4 14.0 1.9e-07 31.3 0.1 7.5 2 2 7 9 9 9 9 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC40203.1 - 1.4e-27 92.9 14.7 0.00088 19.2 0.0 9.2 9 0 0 9 9 9 6 Ankyrin repeat DUF1378 PF07125.6 EGC40203.1 - 0.13 12.2 0.1 0.27 11.2 0.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1378) DUF4408 PF14364.1 EGC40204.1 - 0.003 17.0 2.8 0.1 12.1 0.2 3.5 3 0 0 3 3 3 1 Domain of unknown function (DUF4408) DUF4234 PF14018.1 EGC40204.1 - 0.12 12.1 11.3 2.8 7.7 0.3 3.3 2 1 1 3 3 3 0 Domain of unknown function (DUF4234) TIG PF01833.19 EGC40205.1 - 0.0004 20.3 4.7 0.022 14.7 0.2 2.5 1 1 1 2 2 2 2 IPT/TIG domain RNA_pol_Rpb4 PF03874.11 EGC40206.1 - 3.9e-24 84.9 2.9 5.4e-24 84.4 2.0 1.2 1 0 0 1 1 1 1 RNA polymerase Rpb4 PEPcase_2 PF14010.1 EGC40206.1 - 0.079 11.2 0.5 0.086 11.1 0.4 1.0 1 0 0 1 1 1 0 Phosphoenolpyruvate carboxylase Ank_2 PF12796.2 EGC40207.1 - 1.3 9.4 6.1 36 4.7 0.3 3.8 3 1 0 3 3 3 0 Ankyrin repeats (3 copies) Nse4_C PF08743.5 EGC40208.1 - 2.9e-21 75.2 2.3 7.8e-21 73.9 0.1 2.7 3 0 0 3 3 3 1 Nse4 C-terminal Nse4-Nse3_bdg PF15412.1 EGC40208.1 - 2.2e-09 37.0 1.7 5e-09 35.8 1.2 1.6 1 0 0 1 1 1 1 Binding domain of Nse4/EID3 to Nse3-MAGE DegV PF02645.11 EGC40208.1 - 0.03 13.3 0.9 1.2 8.1 0.1 2.2 2 0 0 2 2 2 0 Uncharacterised protein, DegV family COG1307 Sec23_trunk PF04811.10 EGC40209.1 - 1e-64 218.2 0.1 2.2e-64 217.1 0.1 1.5 1 0 0 1 1 1 1 Sec23/Sec24 trunk domain Sec23_helical PF04815.10 EGC40209.1 - 6.5e-32 109.0 0.9 1.3e-31 108.1 0.6 1.5 1 0 0 1 1 1 1 Sec23/Sec24 helical domain Sec23_BS PF08033.7 EGC40209.1 - 1.3e-30 105.7 0.6 2.8e-30 104.6 0.4 1.6 1 0 0 1 1 1 1 Sec23/Sec24 beta-sandwich domain zf-Sec23_Sec24 PF04810.10 EGC40209.1 - 4.1e-14 51.8 8.7 7.3e-14 51.0 6.1 1.4 1 0 0 1 1 1 1 Sec23/Sec24 zinc finger Gelsolin PF00626.17 EGC40209.1 - 2.1e-12 46.5 0.0 4.3e-12 45.5 0.0 1.5 1 0 0 1 1 1 1 Gelsolin repeat TIG PF01833.19 EGC40211.1 - 7.3e-05 22.6 7.9 0.0012 18.7 0.3 3.3 2 2 2 4 4 4 2 IPT/TIG domain TIG PF01833.19 EGC40212.1 - 0.00059 19.7 52.4 0.00062 19.7 1.2 7.6 8 1 0 8 8 8 4 IPT/TIG domain TIG PF01833.19 EGC40213.1 - 8.4e-09 35.3 49.5 0.00013 21.9 1.8 7.6 7 1 0 7 7 7 4 IPT/TIG domain Peptidase_U9 PF03420.8 EGC40213.1 - 0.085 12.1 0.0 0.17 11.1 0.0 1.4 1 0 0 1 1 1 0 Prohead core protein protease CarboxypepD_reg PF13620.1 EGC40216.1 - 0 1580.3 143.0 6.1e-08 32.6 0.1 79.3 77 3 0 77 77 77 77 Carboxypeptidase regulatory-like domain Cna_B PF05738.8 EGC40216.1 - 0 1663.9 309.0 7.5e-11 41.6 0.5 78.2 77 0 0 77 77 77 77 Cna protein B-type domain DUF2012 PF09430.5 EGC40216.1 - 9.5e-106 348.4 52.9 0.038 13.8 0.0 61.6 72 0 0 72 72 71 22 Protein of unknown function (DUF2012) fn3_3 PF14686.1 EGC40216.1 - 3.2e-98 322.0 75.1 3.9 7.6 0.0 67.1 72 0 0 72 72 71 17 Polysaccharide lyase family 4, domain II MG1 PF11974.3 EGC40216.1 - 1.7e-58 195.2 46.1 2.7 8.5 0.0 48.6 57 0 0 57 57 54 7 Alpha-2-macroglobulin MG1 domain DUF4198 PF10670.4 EGC40216.1 - 1.7e-38 132.7 0.0 38 4.1 0.1 42.0 52 0 0 52 52 52 0 Domain of unknown function (DUF4198) Dioxygenase_C PF00775.16 EGC40216.1 - 2.5e-35 121.3 78.3 3.2 6.9 0.0 51.7 64 0 0 64 64 64 6 Dioxygenase UPF1_Zn_bind PF09416.5 EGC40216.1 - 1.2e-20 73.6 0.0 13 5.3 0.0 14.0 14 0 0 14 14 14 0 RNA helicase (UPF2 interacting domain) DUF1416 PF07210.7 EGC40216.1 - 4.4e-18 64.6 0.0 14 5.3 0.0 15.6 16 0 0 16 16 16 0 Protein of unknown function (DUF1416) DUF364 PF04016.7 EGC40216.1 - 0.00014 21.1 9.5 1e+02 2.1 0.0 9.6 12 0 0 12 12 12 0 Domain of unknown function (DUF364) Inh PF02974.9 EGC40216.1 - 0.17 11.5 17.3 4e+02 0.6 0.0 14.6 19 0 0 19 19 19 0 Protease inhibitor Inh ImpE PF07024.8 EGC40216.1 - 0.34 10.8 11.7 6.6e+02 0.2 0.0 9.4 11 0 0 11 11 11 0 ImpE protein Ribosomal_L9_C PF03948.9 EGC40216.1 - 2 8.5 0.1 7 6.8 0.1 2.0 1 0 0 1 1 1 0 Ribosomal protein L9, C-terminal domain NTP_transf_4 PF13562.1 EGC40216.1 - 2.5 7.7 0.0 1.8e+02 1.7 0.0 4.2 6 0 0 6 6 5 0 Sugar nucleotidyl transferase UPF0560 PF10577.4 EGC40216.1 - 8.2 4.5 0.2 1.5e+02 0.3 0.1 3.1 2 0 0 2 2 2 0 Uncharacterised protein family UPF0560 Pro_isomerase PF00160.16 EGC40217.1 - 1.2e-40 139.2 0.5 2.4e-40 138.2 0.3 1.5 1 0 0 1 1 1 1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD RRM_1 PF00076.17 EGC40217.1 - 1.4e-15 56.6 0.0 4e-15 55.1 0.0 1.9 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC40217.1 - 1.3e-12 47.4 0.0 5.8e-12 45.4 0.0 2.1 2 0 0 2 2 2 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC40217.1 - 5e-09 35.8 0.1 1.3e-08 34.5 0.1 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) p450 PF00067.17 EGC40218.1 - 5.7e-96 321.8 0.1 1.6e-95 320.3 0.0 1.8 2 0 0 2 2 2 1 Cytochrome P450 EGF_2 PF07974.8 EGC40218.1 - 0.018 15.1 11.7 0.049 13.7 8.1 1.8 1 0 0 1 1 1 0 EGF-like domain TIG PF01833.19 EGC40219.1 - 0.00014 21.7 38.0 0.0013 18.6 0.2 6.6 7 0 0 7 7 7 4 IPT/TIG domain TIG PF01833.19 EGC40220.1 - 9.7e-05 22.2 45.6 0.00027 20.8 1.4 6.9 7 0 0 7 7 7 3 IPT/TIG domain Actin PF00022.14 EGC40221.1 - 1.3e-162 540.7 0.0 1.4e-162 540.6 0.0 1.0 1 0 0 1 1 1 1 Actin ESSS PF10183.4 EGC40221.1 - 0.083 13.2 0.0 0.21 11.9 0.0 1.7 1 1 0 1 1 1 0 ESSS subunit of NADH:ubiquinone oxidoreductase (complex I) CTP_transf_2 PF01467.21 EGC40222.1 - 1.1e-34 119.7 0.0 1.9e-18 66.9 0.0 2.2 2 0 0 2 2 2 2 Cytidylyltransferase FAD_syn PF06574.7 EGC40222.1 - 7.9e-05 22.3 4.2 0.52 9.9 0.1 3.8 2 2 0 2 2 2 2 FAD synthetase Lactamase_B_3 PF13483.1 EGC40222.1 - 0.0015 18.2 0.1 0.039 13.6 0.0 2.1 2 0 0 2 2 2 1 Beta-lactamase superfamily domain CoA_binding_3 PF13727.1 EGC40222.1 - 0.056 13.2 0.0 0.55 10.0 0.0 2.0 2 0 0 2 2 2 0 CoA-binding domain NAAA-beta PF15508.1 EGC40223.1 - 0.00051 20.3 0.0 0.003 17.8 0.0 2.1 1 1 1 2 2 2 1 beta subunit of N-acylethanolamine-hydrolyzing acid amidase AAT PF03417.11 EGC40223.1 - 0.0013 18.2 0.0 0.0028 17.1 0.0 1.5 1 0 0 1 1 1 1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase DOMON PF03351.12 EGC40224.1 - 3.2e-25 88.4 0.6 5e-25 87.8 0.4 1.3 1 0 0 1 1 1 1 DOMON domain Cytochrom_B561 PF03188.11 EGC40224.1 - 3.7e-12 46.2 16.5 7.2e-12 45.3 11.4 1.5 1 0 0 1 1 1 1 Eukaryotic cytochrome b561 DUF2427 PF10348.4 EGC40224.1 - 0.00061 19.3 9.1 0.00061 19.3 6.3 2.3 2 1 0 2 2 2 1 Domain of unknown function (DUF2427) Zn_dep_PLPC PF00882.13 EGC40224.1 - 0.0065 16.1 0.3 0.31 10.6 0.1 2.5 1 1 1 2 2 2 1 Zinc dependent phospholipase C 7TMR-DISM_7TM PF07695.6 EGC40224.1 - 0.91 9.1 27.7 0.67 9.5 10.7 2.4 1 1 1 2 2 2 0 7TM diverse intracellular signalling DUF373 PF04123.8 EGC40224.1 - 0.92 8.4 8.1 1.3 7.9 5.6 1.2 1 0 0 1 1 1 0 Domain of unknown function (DUF373) FtsX PF02687.16 EGC40224.1 - 1.4 8.6 15.6 6.1e+03 -3.1 10.8 2.8 1 1 0 1 1 1 0 FtsX-like permease family Pkinase PF00069.20 EGC40225.1 - 3.8e-66 222.8 0.2 5.4e-66 222.3 0.1 1.2 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40225.1 - 8.9e-29 100.3 0.0 1.5e-28 99.6 0.0 1.3 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC40225.1 - 1.1e-05 24.5 0.0 7.1e-05 21.8 0.0 1.9 1 1 0 2 2 2 1 Kinase-like Kdo PF06293.9 EGC40225.1 - 0.00028 20.0 0.0 0.0005 19.1 0.0 1.4 1 0 0 1 1 1 1 Lipopolysaccharide kinase (Kdo/WaaP) family APH PF01636.18 EGC40225.1 - 0.00073 19.3 0.0 0.022 14.4 0.0 2.3 1 1 1 2 2 2 1 Phosphotransferase enzyme family Choline_kinase PF01633.15 EGC40225.1 - 0.0032 17.0 3.8 0.0047 16.5 0.4 2.3 2 1 0 2 2 2 1 Choline/ethanolamine kinase Fructosamin_kin PF03881.9 EGC40225.1 - 0.016 14.1 0.9 0.025 13.5 0.6 1.3 1 0 0 1 1 1 0 Fructosamine kinase ArfGap PF01412.13 EGC40225.1 - 5.5 6.8 8.9 0.17 11.6 0.8 2.2 2 0 0 2 2 2 0 Putative GTPase activating protein for Arf DUF1510 PF07423.6 EGC40226.1 - 0.19 11.0 6.1 0.28 10.5 4.2 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF1510) DDE_3 PF13358.1 EGC40227.1 - 4e-07 29.8 0.0 7.1e-07 29.0 0.0 1.4 1 1 0 1 1 1 1 DDE superfamily endonuclease LAP2alpha PF11560.3 EGC40227.1 - 0.13 11.4 0.0 0.22 10.6 0.0 1.4 2 0 0 2 2 2 0 Lamina-associated polypeptide 2 alpha DUF2361 PF10153.4 EGC40229.1 - 0.02 15.0 1.7 0.023 14.8 1.2 1.1 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2361) GTP_cyclohydroI PF01227.17 EGC40229.1 - 0.022 14.0 0.4 0.029 13.6 0.3 1.1 1 0 0 1 1 1 0 GTP cyclohydrolase I DUF3993 PF13158.1 EGC40229.1 - 0.052 13.3 0.6 0.059 13.1 0.4 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3993) PRF PF06875.6 EGC40229.1 - 0.072 12.3 0.3 0.081 12.1 0.2 1.1 1 0 0 1 1 1 0 Plethodontid receptivity factor PRF Focal_AT PF03623.8 EGC40229.1 - 0.098 12.1 3.0 0.12 11.8 2.1 1.1 1 0 0 1 1 1 0 Focal adhesion targeting region DUF3186 PF11382.3 EGC40229.1 - 0.15 11.1 0.1 0.15 11.1 0.1 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) Prosystemin PF07376.6 EGC40229.1 - 0.15 11.3 1.5 0.17 11.2 1.1 1.1 1 0 0 1 1 1 0 Prosystemin Rho_Binding PF08912.6 EGC40229.1 - 0.44 10.8 6.7 0.64 10.3 4.6 1.2 1 0 0 1 1 1 0 Rho Binding MAPEG PF01124.13 EGC40230.1 - 1.7e-29 102.0 0.0 2e-29 101.8 0.0 1.0 1 0 0 1 1 1 1 MAPEG family Cys_rich_FGFR PF00839.12 EGC40231.1 - 0.088 12.7 0.1 2 8.3 0.0 2.2 2 0 0 2 2 2 0 Cysteine rich repeat AhpC-TSA PF00578.16 EGC40232.1 - 1.2e-40 138.0 0.1 1.4e-40 137.8 0.1 1.1 1 0 0 1 1 1 1 AhpC/TSA family Redoxin PF08534.5 EGC40232.1 - 3.9e-24 84.8 0.1 4.4e-24 84.6 0.0 1.0 1 0 0 1 1 1 1 Redoxin AhpC-TSA_2 PF13911.1 EGC40232.1 - 0.0024 17.7 0.0 0.0031 17.4 0.0 1.2 1 0 0 1 1 1 1 AhpC/TSA antioxidant enzyme GSHPx PF00255.14 EGC40232.1 - 0.024 14.0 0.0 0.041 13.2 0.0 1.4 1 0 0 1 1 1 0 Glutathione peroxidase EGF_2 PF07974.8 EGC40233.1 - 5.7e-12 45.5 67.4 0.00029 20.9 5.7 4.7 4 0 0 4 4 4 4 EGF-like domain TIG PF01833.19 EGC40233.1 - 4e-10 39.5 9.7 4.4e-06 26.5 0.3 6.2 6 1 1 7 7 7 2 IPT/TIG domain LRR_8 PF13855.1 EGC40233.1 - 0.00014 21.5 9.7 0.078 12.7 4.0 3.4 1 1 1 2 2 2 2 Leucine rich repeat Laminin_EGF PF00053.19 EGC40233.1 - 0.00041 20.2 50.1 0.0032 17.3 4.5 4.6 2 1 2 4 4 4 2 Laminin EGF-like (Domains III and V) SKG6 PF08693.5 EGC40233.1 - 0.11 11.7 5.1 0.24 10.7 3.5 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain LRR_1 PF00560.28 EGC40233.1 - 0.24 11.5 19.2 3.1 8.1 0.1 6.3 5 1 1 6 6 6 0 Leucine Rich Repeat LRR_4 PF12799.2 EGC40233.1 - 0.37 10.4 23.2 0.32 10.6 3.9 4.7 3 1 2 5 5 5 0 Leucine Rich repeats (2 copies) DUF4519 PF15012.1 EGC40233.1 - 1.7 8.6 2.9 3.6 7.5 2.0 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4519) hEGF PF12661.2 EGC40233.1 - 2.1 8.5 25.6 0.33 11.1 1.1 5.3 4 1 0 4 4 4 0 Human growth factor-like EGF LRR_7 PF13504.1 EGC40233.1 - 3.4 8.2 9.5 61 4.4 0.0 5.3 4 0 0 4 4 4 0 Leucine rich repeat Kinesin PF00225.18 EGC40234.1 - 1.2e-106 356.1 0.5 1.2e-106 356.1 0.4 4.4 5 0 0 5 5 5 1 Kinesin motor domain DUF3357 PF11837.3 EGC40234.1 - 0.036 13.8 0.1 0.036 13.8 0.0 2.8 2 0 0 2 2 2 0 Domain of unknown function (DUF3357) DUF1192 PF06698.6 EGC40234.1 - 0.32 10.8 5.0 0.31 10.8 1.4 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF1192) Ribosomal_L19e PF01280.15 EGC40235.1 - 2.7e-61 205.7 10.0 2.7e-61 205.7 6.9 1.5 1 1 1 2 2 2 1 Ribosomal protein L19e Mur_ligase_M PF08245.7 EGC40235.1 - 0.26 11.3 1.2 0.39 10.7 0.9 1.2 1 0 0 1 1 1 0 Mur ligase middle domain Sec62 PF03839.11 EGC40235.1 - 1.2 8.5 6.2 8.1 5.7 0.0 2.1 2 0 0 2 2 2 0 Translocation protein Sec62 EGF_CA PF07645.10 EGC40236.1 - 3.1e-17 62.2 39.2 1.7e-08 34.2 5.8 3.1 3 0 0 3 3 3 3 Calcium-binding EGF domain FXa_inhibition PF14670.1 EGC40236.1 - 1.2e-10 41.2 31.9 6.3e-07 29.4 4.5 3.2 3 0 0 3 3 3 3 Coagulation Factor Xa inhibitory site cEGF PF12662.2 EGC40236.1 - 5.8e-10 38.6 10.6 8.7e-06 25.2 1.2 3.9 4 0 0 4 4 4 2 Complement Clr-like EGF-like EGF PF00008.22 EGC40236.1 - 1.1e-07 31.7 26.0 0.0003 20.6 2.2 3.7 3 1 1 4 4 4 3 EGF-like domain EGF_3 PF12947.2 EGC40236.1 - 5.2e-06 26.3 25.1 0.0066 16.3 1.9 3.8 3 2 0 3 3 3 3 EGF domain hEGF PF12661.2 EGC40236.1 - 0.0038 17.2 5.0 0.68 10.1 0.4 3.2 2 0 0 2 2 2 2 Human growth factor-like EGF EGF_MSP1_1 PF12946.2 EGC40236.1 - 0.069 12.9 1.2 0.069 12.9 0.8 4.4 1 1 2 3 3 3 0 MSP1 EGF domain 1 zf-RING_2 PF13639.1 EGC40237.1 - 4.7e-12 45.5 3.1 8.7e-12 44.6 2.1 1.4 1 0 0 1 1 1 1 Ring finger domain zf-rbx1 PF12678.2 EGC40237.1 - 1.4e-08 34.6 0.6 4.2e-08 33.1 0.4 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC40237.1 - 3.7e-07 30.0 3.4 8.2e-07 28.9 2.3 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40237.1 - 1.6e-06 27.6 2.9 3.7e-06 26.5 2.0 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4 PF00097.20 EGC40237.1 - 1e-05 25.0 4.4 1e-05 25.0 3.0 2.1 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_UBOX PF13445.1 EGC40237.1 - 8.2e-05 22.2 3.9 0.00039 20.0 2.7 2.3 1 0 0 1 1 1 1 RING-type zinc-finger zf-C3HC4_3 PF13920.1 EGC40237.1 - 0.00019 21.0 0.9 0.00037 20.0 0.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-Apc11 PF12861.2 EGC40237.1 - 0.00067 19.4 0.6 0.0013 18.4 0.4 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger FANCL_C PF11793.3 EGC40237.1 - 0.011 15.6 1.4 0.036 14.0 1.0 1.9 1 0 0 1 1 1 0 FANCL C-terminal domain zf-Nse PF11789.3 EGC40237.1 - 0.017 14.6 1.5 0.046 13.2 1.0 1.7 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit zf-C3HC4_4 PF15227.1 EGC40237.1 - 0.022 14.6 2.9 0.085 12.7 2.1 2.0 1 1 0 1 1 1 0 zinc finger of C3HC4-type, RING RINGv PF12906.2 EGC40237.1 - 0.056 13.4 3.6 0.17 11.9 2.5 1.9 1 0 0 1 1 1 0 RING-variant domain zf-RING_6 PF14835.1 EGC40237.1 - 0.17 11.7 0.9 0.36 10.6 0.6 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein MutS_V PF00488.16 EGC40238.1 - 1.4e-86 289.6 0.0 2.4e-86 288.9 0.0 1.4 1 0 0 1 1 1 1 MutS domain V MutS_III PF05192.13 EGC40238.1 - 1.3e-32 113.2 0.6 1.3e-32 113.2 0.4 2.0 2 0 0 2 2 2 1 MutS domain III MutS_I PF01624.15 EGC40238.1 - 1.9e-29 102.0 0.0 5.8e-29 100.3 0.0 1.9 1 0 0 1 1 1 1 MutS domain I MutS_II PF05188.12 EGC40238.1 - 9e-14 51.7 1.1 4e-13 49.5 0.1 2.7 2 0 0 2 2 2 1 MutS domain II MutS_IV PF05190.13 EGC40238.1 - 3.2e-06 27.2 2.2 7.2e-06 26.0 0.6 2.4 2 0 0 2 2 2 1 MutS family domain IV DUF4637 PF15470.1 EGC40238.1 - 0.32 10.5 1.9 0.68 9.5 1.3 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4637) zf-MYND PF01753.13 EGC40239.1 - 1.6e-08 34.2 14.6 3.9e-08 33.0 10.1 1.7 1 0 0 1 1 1 1 MYND finger SET PF00856.23 EGC40239.1 - 4e-07 30.4 0.1 0.00017 21.9 0.1 2.5 2 0 0 2 2 2 2 SET domain Septin PF00735.13 EGC40240.1 - 1.7e-09 37.0 0.1 1.7e-09 37.0 0.1 2.4 2 0 0 2 2 2 1 Septin MMR_HSR1 PF01926.18 EGC40240.1 - 7.4e-08 32.3 0.1 3.6e-07 30.1 0.1 2.3 1 0 0 1 1 1 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC40240.1 - 2.5e-07 30.0 2.7 3e-07 29.7 0.0 2.4 2 0 0 2 2 2 1 Protein of unknown function, DUF258 Dynamin_N PF00350.18 EGC40240.1 - 0.00079 19.2 15.7 0.0043 16.8 0.0 4.6 5 0 0 5 5 5 2 Dynamin family FtsK_SpoIIIE PF01580.13 EGC40240.1 - 0.013 14.9 0.0 0.027 13.9 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGC40240.1 - 0.021 14.3 0.0 0.054 13.0 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC40240.1 - 0.031 14.2 0.0 0.083 12.8 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGC40240.1 - 0.084 13.1 0.0 0.084 13.1 0.0 2.8 2 1 0 2 2 2 0 ABC transporter MMR_HSR1 PF01926.18 EGC40241.1 - 6e-08 32.6 2.9 1.1e-07 31.8 0.1 2.9 3 0 0 3 3 3 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC40241.1 - 7.2e-08 31.7 0.0 2.3e-07 30.1 0.0 1.9 1 0 0 1 1 1 1 Protein of unknown function, DUF258 Septin PF00735.13 EGC40241.1 - 7.8e-08 31.6 0.0 7.8e-08 31.6 0.0 2.2 2 0 0 2 2 2 1 Septin AIG1 PF04548.11 EGC40241.1 - 1.4e-06 27.6 0.1 0.032 13.3 0.0 2.6 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 EGC40241.1 - 0.0024 17.6 15.2 0.011 15.5 0.0 4.6 4 1 0 4 4 4 2 Dynamin family AAA_16 PF13191.1 EGC40241.1 - 0.012 15.6 0.0 0.028 14.4 0.0 1.6 1 0 0 1 1 1 0 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGC40241.1 - 0.016 14.7 0.0 0.029 13.8 0.0 1.3 1 0 0 1 1 1 0 FtsK/SpoIIIE family PDDEXK_1 PF12705.2 EGC40241.1 - 0.016 14.5 0.1 0.045 13.1 0.0 1.7 1 0 0 1 1 1 0 PD-(D/E)XK nuclease superfamily AAA_29 PF13555.1 EGC40241.1 - 0.027 14.0 0.0 0.061 12.8 0.0 1.5 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC40241.1 - 0.038 14.2 0.4 0.18 12.0 0.0 2.4 2 0 0 2 2 2 0 ABC transporter DUF258 PF03193.11 EGC40242.1 - 0.0055 15.9 0.1 0.018 14.2 0.1 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AAA_29 PF13555.1 EGC40242.1 - 0.0067 15.9 0.0 0.014 14.9 0.0 1.4 1 0 0 1 1 1 1 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC40242.1 - 0.0099 16.1 0.1 0.031 14.5 0.1 1.8 1 0 0 1 1 1 1 ABC transporter FtsK_SpoIIIE PF01580.13 EGC40242.1 - 0.019 14.4 0.0 0.048 13.1 0.0 1.6 1 0 0 1 1 1 0 FtsK/SpoIIIE family MMR_HSR1 PF01926.18 EGC40242.1 - 0.02 14.8 1.8 0.038 13.9 0.1 2.4 2 0 0 2 2 2 0 50S ribosome-binding GTPase TrwB_AAD_bind PF10412.4 EGC40242.1 - 0.048 12.2 0.2 4.1 5.9 0.0 2.2 2 0 0 2 2 2 0 Type IV secretion-system coupling protein DNA-binding domain Septin PF00735.13 EGC40243.1 - 5.6e-10 38.7 0.1 2.6e-09 36.5 0.1 2.2 1 0 0 1 1 1 1 Septin DUF258 PF03193.11 EGC40243.1 - 1.1e-07 31.1 0.0 4.1e-07 29.3 0.0 2.0 1 0 0 1 1 1 1 Protein of unknown function, DUF258 MMR_HSR1 PF01926.18 EGC40243.1 - 3.9e-07 30.0 4.0 4.6e-07 29.8 0.1 3.2 3 0 0 3 3 3 1 50S ribosome-binding GTPase Dynamin_N PF00350.18 EGC40243.1 - 0.00026 20.8 13.8 0.0037 17.1 0.0 4.8 5 0 0 5 5 5 2 Dynamin family FtsK_SpoIIIE PF01580.13 EGC40243.1 - 0.014 14.9 0.0 0.028 13.8 0.0 1.4 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGC40243.1 - 0.022 14.2 0.0 0.056 12.9 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain AAA_16 PF13191.1 EGC40243.1 - 0.033 14.1 0.0 0.092 12.7 0.0 1.7 1 0 0 1 1 1 0 AAA ATPase domain ABC_tran PF00005.22 EGC40243.1 - 0.063 13.5 2.1 0.22 11.8 0.4 2.7 2 1 0 2 2 2 0 ABC transporter Septin PF00735.13 EGC40245.1 - 6.4e-11 41.7 0.0 2.2e-10 40.0 0.0 1.9 1 0 0 1 1 1 1 Septin MMR_HSR1 PF01926.18 EGC40245.1 - 2.8e-08 33.7 0.4 1.7e-07 31.2 0.1 2.6 2 0 0 2 2 2 1 50S ribosome-binding GTPase DUF258 PF03193.11 EGC40245.1 - 3.8e-07 29.4 0.0 1.1e-06 27.9 0.0 1.8 1 0 0 1 1 1 1 Protein of unknown function, DUF258 AIG1 PF04548.11 EGC40245.1 - 3.1e-05 23.1 0.0 0.25 10.4 0.0 2.5 2 0 0 2 2 2 2 AIG1 family Dynamin_N PF00350.18 EGC40245.1 - 0.00041 20.2 7.3 0.012 15.4 0.0 3.5 4 0 0 4 4 4 2 Dynamin family AAA_16 PF13191.1 EGC40245.1 - 0.0089 16.0 0.0 0.019 14.9 0.0 1.5 1 0 0 1 1 1 1 AAA ATPase domain FtsK_SpoIIIE PF01580.13 EGC40245.1 - 0.017 14.6 0.0 0.035 13.5 0.0 1.5 1 0 0 1 1 1 0 FtsK/SpoIIIE family AAA_29 PF13555.1 EGC40245.1 - 0.079 12.5 0.0 0.2 11.2 0.0 1.6 1 0 0 1 1 1 0 P-loop containing region of AAA domain ABC_tran PF00005.22 EGC40245.1 - 0.15 12.3 1.9 0.35 11.1 0.1 2.4 2 1 0 2 2 2 0 ABC transporter RRM_3 PF08777.6 EGC40246.1 - 3.2e-27 94.4 1.7 3.2e-27 94.4 1.2 2.6 2 1 0 2 2 2 1 RNA binding motif La PF05383.12 EGC40246.1 - 1.4e-24 85.6 1.0 2.9e-24 84.6 0.7 1.6 1 0 0 1 1 1 1 La domain RRM_6 PF14259.1 EGC40246.1 - 1.1e-15 57.3 0.1 6.2e-09 35.7 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC40246.1 - 2.5e-13 49.4 3.9 1.7e-07 30.7 0.2 3.3 2 1 1 3 3 3 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC40246.1 - 2.3e-10 40.1 0.1 1.2e-05 25.0 0.0 2.5 2 0 0 2 2 2 2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) DUF4632 PF15451.1 EGC40246.1 - 1.5 8.7 3.6 3.6 7.5 2.5 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF4632) F-box-like PF12937.2 EGC40247.1 - 9.1e-05 22.1 1.0 0.00026 20.6 0.1 2.1 2 0 0 2 2 2 1 F-box-like DUF3440 PF11922.3 EGC40247.1 - 0.0099 15.4 3.7 0.017 14.6 2.6 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3440) LRR_6 PF13516.1 EGC40248.1 - 2.8e-16 57.7 45.6 0.045 13.8 0.2 10.7 11 0 0 11 11 11 7 Leucine Rich repeat LRR_1 PF00560.28 EGC40248.1 - 0.00043 19.9 45.5 1.6 9.0 0.4 10.4 10 1 0 10 10 10 4 Leucine Rich Repeat LRR_8 PF13855.1 EGC40248.1 - 0.0063 16.2 56.1 0.26 11.0 1.3 7.6 3 3 4 7 7 7 6 Leucine rich repeat SpoU_sub_bind PF08032.7 EGC40248.1 - 0.013 15.6 0.1 0.78 9.9 0.0 2.9 3 0 0 3 3 3 0 RNA 2'-O ribose methyltransferase substrate binding LRR_4 PF12799.2 EGC40248.1 - 0.019 14.5 57.9 0.76 9.4 0.3 8.1 3 1 4 8 8 8 0 Leucine Rich repeats (2 copies) LRR_2 PF07723.8 EGC40248.1 - 0.041 14.3 9.1 3.5 8.2 0.0 5.6 6 0 0 6 6 6 0 Leucine Rich Repeat LRR_7 PF13504.1 EGC40248.1 - 0.077 13.2 26.2 2.1 8.9 0.1 9.0 10 0 0 10 10 10 0 Leucine rich repeat Plasmid_parti PF01672.11 EGC40248.1 - 7.3 7.1 8.7 29 5.1 0.3 3.9 3 2 0 3 3 3 0 Putative plasmid partition protein Abhydrolase_5 PF12695.2 EGC40249.1 - 7e-10 38.8 0.0 9e-10 38.4 0.0 1.2 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC40249.1 - 4.7e-07 29.6 0.1 0.00025 20.6 0.0 2.2 1 1 1 2 2 2 2 alpha/beta hydrolase fold Abhydrolase_6 PF12697.2 EGC40249.1 - 1.6e-06 28.1 0.0 1e-05 25.5 0.0 1.7 1 1 1 2 2 2 1 Alpha/beta hydrolase family DLH PF01738.13 EGC40249.1 - 1e-05 24.9 0.0 1.5e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 Dienelactone hydrolase family Peptidase_S9 PF00326.16 EGC40249.1 - 0.0067 15.6 0.0 0.57 9.3 0.0 2.2 1 1 1 2 2 2 2 Prolyl oligopeptidase family DUF410 PF04190.8 EGC40250.1 - 6.4e-45 153.7 0.4 9.7e-45 153.1 0.3 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF410) Nuc_sug_transp PF04142.10 EGC40251.1 - 5.3e-10 38.8 10.0 5.3e-10 38.8 6.9 1.6 1 1 0 1 1 1 1 Nucleotide-sugar transporter EamA PF00892.15 EGC40251.1 - 2.3e-08 34.0 3.2 2.3e-08 34.0 2.2 4.6 3 2 1 4 4 4 1 EamA-like transporter family TPT PF03151.11 EGC40251.1 - 2e-06 27.5 28.1 8.2e-06 25.5 6.2 3.5 2 2 0 3 3 3 2 Triose-phosphate Transporter family EmrE PF13536.1 EGC40251.1 - 4.3e-05 23.6 1.9 4.3e-05 23.6 1.3 4.5 3 1 1 4 4 4 3 Multidrug resistance efflux transporter Tubulin PF00091.20 EGC40252.1 - 7.5e-71 238.3 0.0 1.3e-70 237.5 0.0 1.4 1 0 0 1 1 1 1 Tubulin/FtsZ family, GTPase domain Tubulin_C PF03953.12 EGC40252.1 - 1.1e-38 132.1 0.0 2.1e-38 131.1 0.0 1.5 1 0 0 1 1 1 1 Tubulin C-terminal domain Tubulin_3 PF14881.1 EGC40252.1 - 0.00036 20.0 0.0 0.0011 18.4 0.0 1.9 2 0 0 2 2 2 1 Tubulin domain DUF2828 PF11443.3 EGC40254.1 - 8.2e-161 535.8 0.4 2.4e-137 458.3 0.5 2.0 1 1 1 2 2 2 2 Domain of unknown function (DUF2828) VWA_CoxE PF05762.9 EGC40254.1 - 0.088 11.9 0.0 0.19 10.8 0.0 1.4 1 1 0 1 1 1 0 VWA domain containing CoxE-like protein Abhydrolase_6 PF12697.2 EGC40255.1 - 3.3e-29 102.3 0.0 4.1e-29 102.0 0.0 1.1 1 0 0 1 1 1 1 Alpha/beta hydrolase family Abhydrolase_1 PF00561.15 EGC40255.1 - 7.3e-24 84.5 0.0 1.3e-23 83.7 0.0 1.4 1 1 0 1 1 1 1 alpha/beta hydrolase fold Abhydrolase_5 PF12695.2 EGC40255.1 - 7.2e-15 55.0 0.0 1.9e-14 53.6 0.0 1.7 1 1 0 1 1 1 1 Alpha/beta hydrolase family Peptidase_S9 PF00326.16 EGC40255.1 - 5e-05 22.6 0.7 0.00081 18.6 0.0 2.5 2 1 0 2 2 2 1 Prolyl oligopeptidase family DLH PF01738.13 EGC40255.1 - 0.0013 18.0 0.0 0.87 8.8 0.0 2.3 2 0 0 2 2 2 2 Dienelactone hydrolase family Ndr PF03096.9 EGC40255.1 - 0.0035 15.8 0.0 0.0069 14.9 0.0 1.5 1 1 0 1 1 1 1 Ndr family Hydrolase_4 PF12146.3 EGC40255.1 - 0.018 14.9 0.0 0.033 14.0 0.0 1.4 1 0 0 1 1 1 0 Putative lysophospholipase Abhydrolase_4 PF08386.5 EGC40255.1 - 0.02 14.7 0.0 0.035 13.9 0.0 1.3 1 0 0 1 1 1 0 TAP-like protein Abhydrolase_3 PF07859.8 EGC40255.1 - 0.051 13.1 0.0 0.45 10.0 0.0 2.0 1 1 0 1 1 1 0 alpha/beta hydrolase fold Thioesterase PF00975.15 EGC40255.1 - 0.072 13.3 0.0 1.8 8.7 0.0 2.1 2 0 0 2 2 2 0 Thioesterase domain Esterase PF00756.15 EGC40255.1 - 0.15 11.4 0.0 0.27 10.5 0.0 1.3 1 0 0 1 1 1 0 Putative esterase CTD_bind PF04818.8 EGC40256.1 - 0.02 15.1 0.4 0.05 13.8 0.2 1.7 1 1 1 2 2 2 0 RNA polymerase II-binding domain. DUF3195 PF11424.3 EGC40256.1 - 0.026 14.6 1.8 0.029 14.5 0.9 1.4 1 1 0 1 1 1 0 Protein of unknown function (DUF3195) NUMOD3 PF07460.6 EGC40256.1 - 0.065 13.1 0.2 0.12 12.3 0.1 1.5 1 0 0 1 1 1 0 NUMOD3 motif (2 copies) DUF4557 PF15101.1 EGC40257.1 - 8.6e-05 22.4 5.8 8.6e-05 22.4 4.0 2.7 2 1 0 2 2 2 1 Domain of unknown function (DUF4557) FNIP PF05725.7 EGC40258.1 - 6.7e-71 234.0 60.4 3.2e-13 49.3 0.9 11.1 5 2 7 13 13 13 13 FNIP Repeat FNIP PF05725.7 EGC40259.1 - 1.4e-66 220.2 60.2 6.1e-10 38.8 3.4 12.3 2 2 10 14 14 14 14 FNIP Repeat Peptidase_M24 PF00557.19 EGC40260.1 - 2.9e-57 193.5 0.0 3.9e-57 193.1 0.0 1.2 1 0 0 1 1 1 1 Metallopeptidase family M24 AMP_N PF05195.11 EGC40260.1 - 2.1e-30 104.8 0.0 3.5e-30 104.1 0.0 1.3 1 0 0 1 1 1 1 Aminopeptidase P, N-terminal domain Aldolase_II PF00596.16 EGC40261.1 - 2.2e-42 144.7 0.1 2.7e-42 144.4 0.0 1.1 1 0 0 1 1 1 1 Class II Aldolase and Adducin N-terminal domain Phage_Mu_Gp45 PF06890.7 EGC40261.1 - 0.066 12.6 0.2 0.25 10.7 0.0 1.8 1 1 1 2 2 2 0 Bacteriophage Mu Gp45 protein Isochorismatase PF00857.15 EGC40262.1 - 4.2e-34 117.9 0.0 5.2e-34 117.6 0.0 1.1 1 0 0 1 1 1 1 Isochorismatase family zf-RING_2 PF13639.1 EGC40263.1 - 8.5e-11 41.5 11.6 2.3e-10 40.1 7.9 1.9 2 0 0 2 2 2 1 Ring finger domain zf-rbx1 PF12678.2 EGC40263.1 - 2.9e-07 30.5 6.4 7.6e-07 29.1 4.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC40263.1 - 5.4e-07 29.1 14.2 1.4e-06 27.8 9.8 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC40263.1 - 9.2e-07 28.4 10.7 2e-06 27.3 7.4 1.6 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40263.1 - 1.1e-05 25.3 16.2 1.1e-05 25.2 9.9 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40263.1 - 0.0014 18.2 13.1 0.0014 18.2 9.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC40263.1 - 0.016 14.9 2.8 0.041 13.7 1.9 1.7 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC40263.1 - 0.071 12.9 13.1 0.21 11.4 9.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC40263.1 - 0.63 9.8 6.4 1.3 8.8 4.4 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein TFIIA PF03153.8 EGC40263.1 - 4 7.2 66.7 4.3 7.1 35.3 2.3 1 1 1 2 2 2 0 Transcription factor IIA, alpha/beta subunit Baculo_11_kDa PF06143.6 EGC40264.1 - 0.026 13.8 0.1 0.098 12.0 0.1 1.9 1 0 0 1 1 1 0 Baculovirus 11 kDa family Glyco_hydro_79n PF03662.9 EGC40264.1 - 0.031 12.8 0.2 0.038 12.6 0.1 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 79, N-terminal domain DUF4083 PF13314.1 EGC40264.1 - 0.088 12.6 6.6 4.2 7.2 0.1 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) PCEMA1 PF07418.6 EGC40264.1 - 0.19 11.0 9.6 0.21 10.9 6.6 1.1 1 0 0 1 1 1 0 Acidic phosphoprotein precursor PCEMA1 DUF4446 PF14584.1 EGC40264.1 - 1.2 8.9 12.1 0.38 10.5 0.3 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Birna_RdRp PF04197.7 EGC40264.1 - 3.1 5.7 11.6 3.8 5.4 8.1 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) zf-RING_2 PF13639.1 EGC40266.1 - 7.9e-11 41.6 11.4 1.9e-10 40.4 7.9 1.7 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC40266.1 - 2.3e-07 30.3 8.8 4.4e-07 29.4 6.1 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC40266.1 - 2.5e-07 30.6 6.4 6.1e-07 29.4 4.4 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4 PF00097.20 EGC40266.1 - 4.5e-07 29.4 14.2 1.1e-06 28.1 9.8 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40266.1 - 9.2e-06 25.5 14.2 9.2e-06 25.5 9.9 1.8 2 0 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40266.1 - 0.0011 18.5 13.1 0.0011 18.5 9.1 1.8 2 0 0 2 2 2 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC40266.1 - 0.013 15.3 2.7 0.031 14.1 1.9 1.6 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger TFIIA PF03153.8 EGC40266.1 - 0.054 13.3 48.9 0.24 11.2 33.9 1.8 1 1 0 1 1 1 0 Transcription factor IIA, alpha/beta subunit Baculo_RING PF05883.6 EGC40266.1 - 0.058 13.2 7.4 0.17 11.7 5.1 1.8 1 0 0 1 1 1 0 Baculovirus U-box/Ring-like domain zf-C3HC4_4 PF15227.1 EGC40266.1 - 0.059 13.2 13.1 0.17 11.7 9.1 1.9 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC40266.1 - 0.13 12.0 4.6 0.3 10.8 3.2 1.6 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Asp-B-Hydro_N PF05279.6 EGC40266.1 - 6.4 6.5 34.9 0.59 9.9 17.9 2.3 2 0 0 2 2 2 0 Aspartyl beta-hydroxylase N-terminal region DUF1510 PF07423.6 EGC40267.1 - 0.53 9.6 18.8 0.23 10.8 4.4 2.3 2 0 0 2 2 2 0 Protein of unknown function (DUF1510) CDC45 PF02724.9 EGC40267.1 - 8.1 4.3 23.0 3.7 5.4 4.8 2.2 2 0 0 2 2 2 0 CDC45-like protein VWA_2 PF13519.1 EGC40268.1 - 0.011 15.8 0.0 0.028 14.5 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain VWA_2 PF13519.1 EGC40269.1 - 0.026 14.6 0.0 0.064 13.3 0.0 1.6 1 1 0 1 1 1 0 von Willebrand factor type A domain zf-B_box PF00643.19 EGC40270.1 - 1.7e-07 31.0 2.4 3.5e-07 29.9 1.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC40270.1 - 0.024 14.3 2.6 0.037 13.7 0.9 1.9 2 0 0 2 2 2 0 Putative zinc finger in N-recognin (UBR box) DUF2400 PF09674.5 EGC40271.1 - 0.13 11.9 10.6 0.21 11.2 0.1 3.1 2 1 2 4 4 4 0 Protein of unknown function (DUF2400) CPSF_A PF03178.10 EGC40273.1 - 5.7e-101 337.7 0.0 7.4e-99 330.8 0.0 2.7 3 0 0 3 3 3 2 CPSF A subunit region MMS1_N PF10433.4 EGC40273.1 - 2.4e-74 250.3 0.4 5.1e-74 249.2 0.3 1.5 1 0 0 1 1 1 1 Mono-functional DNA-alkylating methyl methanesulfonate N-term Lactonase PF10282.4 EGC40273.1 - 0.013 14.6 0.0 0.46 9.5 0.0 3.0 3 0 0 3 3 3 0 Lactonase, 7-bladed beta-propeller CNH PF00780.17 EGC40273.1 - 0.063 12.6 0.0 0.6 9.4 0.0 2.4 2 0 0 2 2 2 0 CNH domain EF-1_beta_acid PF10587.4 EGC40273.1 - 0.59 10.3 3.5 1.4 9.1 2.4 1.6 1 0 0 1 1 1 0 Eukaryotic elongation factor 1 beta central acidic region zf-FPG_IleRS PF06827.9 EGC40274.1 - 0.18 11.4 2.9 11 5.7 0.1 3.5 3 0 0 3 3 3 0 Zinc finger found in FPG and IleRS DZR PF12773.2 EGC40274.1 - 6.1 6.7 10.0 27 4.6 0.0 3.5 3 1 0 3 3 3 0 Double zinc ribbon Ank_2 PF12796.2 EGC40275.1 - 1.7e-23 82.7 0.8 1.6e-17 63.5 0.0 4.4 3 1 0 3 3 3 2 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC40275.1 - 2.1e-17 61.4 3.3 5.7e-05 22.9 0.0 7.1 6 1 0 6 6 6 5 Ankyrin repeat Ank_4 PF13637.1 EGC40275.1 - 2.4e-16 59.7 1.6 1.8e-10 41.0 0.2 5.4 3 2 3 6 6 6 4 Ankyrin repeats (many copies) Ank PF00023.25 EGC40275.1 - 3.4e-16 58.1 3.0 8.8e-06 25.2 0.0 5.8 5 0 0 5 5 5 3 Ankyrin repeat Ank_5 PF13857.1 EGC40275.1 - 2.3e-11 43.5 14.9 8.5e-10 38.5 0.1 5.9 5 1 3 8 8 8 3 Ankyrin repeats (many copies) Ank_2 PF12796.2 EGC40276.1 - 1e-25 89.8 0.2 1e-15 57.8 0.1 4.2 3 0 0 3 3 3 3 Ankyrin repeats (3 copies) Ank PF00023.25 EGC40276.1 - 1.8e-19 68.4 0.0 0.00022 20.8 0.0 7.5 8 0 0 8 8 8 5 Ankyrin repeat Ank_4 PF13637.1 EGC40276.1 - 1.5e-17 63.5 2.0 1.5e-07 31.7 0.1 6.1 5 2 2 7 7 7 4 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC40276.1 - 1.1e-16 59.2 3.7 0.054 13.7 0.0 7.9 7 1 1 8 8 8 5 Ankyrin repeat Ank_5 PF13857.1 EGC40276.1 - 1.8e-13 50.2 0.0 1.2e-06 28.5 0.0 5.7 4 1 2 6 6 6 2 Ankyrin repeats (many copies) UPF0051 PF01458.12 EGC40278.1 - 0.076 12.4 0.0 0.098 12.0 0.0 1.1 1 0 0 1 1 1 0 Uncharacterized protein family (UPF0051) DUF3645 PF12359.3 EGC40279.1 - 0.0045 16.0 0.1 3.2 6.9 0.0 2.4 2 0 0 2 2 2 2 Protein of unknown function (DUF3645) OTU PF02338.14 EGC40280.1 - 1e-12 48.6 0.0 1e-12 48.6 0.0 2.8 2 1 0 2 2 2 1 OTU-like cysteine protease LMBR1 PF04791.11 EGC40280.1 - 0.036 12.6 1.0 0.034 12.7 0.7 1.1 1 0 0 1 1 1 0 LMBR1-like membrane protein PAT1 PF09770.4 EGC40280.1 - 0.28 9.3 49.4 0.34 9.1 34.2 1.0 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 Band_3_cyto PF07565.8 EGC40280.1 - 0.39 10.1 17.4 0.58 9.6 12.1 1.2 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Neur_chan_memb PF02932.11 EGC40280.1 - 0.4 10.5 5.2 0.61 9.9 3.6 1.3 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Med15 PF09606.5 EGC40280.1 - 0.43 8.7 66.7 0.54 8.4 46.2 1.1 1 0 0 1 1 1 0 ARC105 or Med15 subunit of Mediator complex non-fungal MRP-S26 PF14943.1 EGC40280.1 - 9.6 5.7 27.9 22 4.5 19.2 1.6 1 1 0 1 1 1 0 Mitochondrial ribosome subunit S26 Dimer_Tnp_hAT PF05699.9 EGC40281.1 - 3.2e-15 55.5 0.1 6.9e-15 54.4 0.1 1.6 1 0 0 1 1 1 1 hAT family C-terminal dimerisation region zf-C2H2_6 PF13912.1 EGC40281.1 - 0.022 14.6 0.2 0.049 13.5 0.1 1.6 1 0 0 1 1 1 0 C2H2-type zinc finger Ras PF00071.17 EGC40283.1 - 7e-34 116.5 1.6 9.1e-34 116.1 1.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC40283.1 - 1.6e-12 47.9 0.3 3.5e-12 46.8 0.2 1.6 1 1 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC40283.1 - 9.9e-10 37.9 1.0 1.5e-09 37.3 0.7 1.3 1 0 0 1 1 1 1 ADP-ribosylation factor family Gtr1_RagA PF04670.7 EGC40283.1 - 0.00015 20.9 4.6 0.00019 20.6 3.2 1.2 1 0 0 1 1 1 1 Gtr1/RagA G protein conserved region PduV-EutP PF10662.4 EGC40283.1 - 0.0011 18.4 0.1 1.5 8.3 0.0 2.7 1 1 0 2 2 2 2 Ethanolamine utilisation - propanediol utilisation PTR2 PF00854.16 EGC40284.1 - 7.8e-63 212.4 16.8 2.1e-61 207.8 6.7 2.4 1 1 1 2 2 2 2 POT family OppC_N PF12911.2 EGC40284.1 - 0.03 13.6 0.1 0.15 11.4 0.1 2.2 1 0 0 1 1 1 0 N-terminal TM domain of oligopeptide transport permease C DUF4131 PF13567.1 EGC40284.1 - 1.3 8.3 8.0 0.44 9.9 0.7 3.0 2 1 1 3 3 3 0 Domain of unknown function (DUF4131) Peptidase_M66 PF10462.4 EGC40285.1 - 2e-88 296.1 1.6 2.8e-88 295.7 1.1 1.2 1 0 0 1 1 1 1 Peptidase M66 Reprolysin_2 PF13574.1 EGC40285.1 - 0.033 14.2 0.1 0.095 12.7 0.1 1.8 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like Metallopep PF12044.3 EGC40285.1 - 0.074 11.5 0.4 0.12 10.7 0.3 1.2 1 0 0 1 1 1 0 Putative peptidase family Reprolysin_3 PF13582.1 EGC40285.1 - 0.098 13.1 0.2 0.24 11.9 0.1 1.7 1 0 0 1 1 1 0 Metallo-peptidase family M12B Reprolysin-like ROK PF00480.15 EGC40286.1 - 7.9e-34 117.0 0.2 1.1e-33 116.5 0.1 1.2 1 0 0 1 1 1 1 ROK family Glucokinase PF02685.11 EGC40286.1 - 0.34 9.6 2.9 0.27 9.9 0.1 2.1 3 0 0 3 3 3 0 Glucokinase RRM_1 PF00076.17 EGC40287.1 - 6.4e-14 51.3 0.0 1.8e-13 49.9 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Surp PF01805.15 EGC40287.1 - 6.7e-12 44.8 4.8 1.4e-11 43.8 1.9 2.4 2 0 0 2 2 2 1 Surp module RRM_6 PF14259.1 EGC40287.1 - 4.6e-11 42.5 0.0 1.3e-10 41.1 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) RRM_5 PF13893.1 EGC40287.1 - 5.9e-09 35.6 0.0 1.6e-08 34.2 0.0 1.8 1 0 0 1 1 1 1 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Ribosomal_S26e PF01283.14 EGC40288.1 - 1.9e-47 160.1 10.3 2.1e-47 160.0 7.1 1.0 1 0 0 1 1 1 1 Ribosomal protein S26e Fer4_7 PF12838.2 EGC40288.1 - 0.5 10.7 4.2 4.1 7.8 3.3 2.1 1 1 1 2 2 2 0 4Fe-4S dicluster domain Fer4_10 PF13237.1 EGC40288.1 - 0.92 9.3 5.9 1.7 8.5 1.2 2.0 1 1 1 2 2 2 0 4Fe-4S dicluster domain Nol1_Nop2_Fmu PF01189.12 EGC40289.1 - 6.7e-92 307.8 0.0 1.1e-91 307.0 0.0 1.4 1 0 0 1 1 1 1 NOL1/NOP2/sun family Met_10 PF02475.11 EGC40289.1 - 7.3e-06 25.7 0.1 1.5e-05 24.6 0.0 1.4 1 0 0 1 1 1 1 Met-10+ like-protein Methyltransf_31 PF13847.1 EGC40289.1 - 1.4e-05 24.6 0.1 3.1e-05 23.5 0.0 1.6 1 0 0 1 1 1 1 Methyltransferase domain FtsJ PF01728.14 EGC40289.1 - 3e-05 24.0 0.3 8.7e-05 22.5 0.0 1.9 2 0 0 2 2 2 1 FtsJ-like methyltransferase PCMT PF01135.14 EGC40289.1 - 0.00013 21.6 0.0 0.00025 20.6 0.0 1.4 1 0 0 1 1 1 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) Methyltransf_18 PF12847.2 EGC40289.1 - 0.00018 22.0 0.0 0.0004 20.9 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC40289.1 - 0.00031 20.7 0.0 0.00052 20.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain HNH_2 PF13391.1 EGC40291.1 - 1.9e-08 33.9 0.1 4.4e-08 32.7 0.1 1.6 1 0 0 1 1 1 1 HNH endonuclease DDE_Tnp_4 PF13359.1 EGC40292.1 - 8.5e-06 25.4 0.9 9.6e-06 25.2 0.6 1.1 1 0 0 1 1 1 1 DDE superfamily endonuclease DDE_Tnp_4 PF13359.1 EGC40293.1 - 6.6e-11 42.0 0.4 7.4e-10 38.6 0.0 2.0 2 0 0 2 2 2 1 DDE superfamily endonuclease DDE_Tnp_1 PF01609.16 EGC40293.1 - 0.0024 17.4 0.0 0.0032 17.0 0.0 1.2 1 0 0 1 1 1 1 Transposase DDE domain ATP_synth_reg PF14960.1 EGC40293.1 - 0.0093 15.1 0.7 1 8.6 0.0 2.5 2 0 0 2 2 2 2 ATP synthase regulation HTH_Tnp_4 PF13613.1 EGC40293.1 - 0.02 14.4 0.0 0.037 13.5 0.0 1.4 1 0 0 1 1 1 0 Helix-turn-helix of DDE superfamily endonuclease Guanylate_cyc_2 PF09778.4 EGC40294.1 - 3.7e-44 150.4 6.1 4.4e-30 104.4 0.8 2.1 1 1 1 2 2 2 2 Guanylylate cyclase Peptidase_C39_2 PF13529.1 EGC40294.1 - 1.1e-06 29.1 8.8 0.014 15.7 3.7 3.1 1 1 1 2 2 2 2 Peptidase_C39 like family Peptidase_C39 PF03412.10 EGC40294.1 - 0.00017 21.4 0.4 0.11 12.2 0.0 2.7 2 1 0 2 2 2 2 Peptidase C39 family Transpep_BrtH PF14399.1 EGC40294.1 - 0.0041 16.4 0.0 0.0068 15.7 0.0 1.3 1 0 0 1 1 1 1 NlpC/p60-like transpeptidase Prefoldin_2 PF01920.15 EGC40295.1 - 3e-15 55.8 9.4 4.3e-15 55.3 6.5 1.2 1 0 0 1 1 1 1 Prefoldin subunit Prefoldin PF02996.12 EGC40295.1 - 0.00031 20.3 0.8 0.00031 20.3 0.6 2.1 2 0 0 2 2 2 1 Prefoldin subunit Ecm29 PF13001.2 EGC40295.1 - 0.02 13.3 0.4 0.023 13.2 0.3 1.0 1 0 0 1 1 1 0 Proteasome stabiliser Snf7 PF03357.16 EGC40295.1 - 0.054 12.8 8.3 0.071 12.4 0.2 2.1 2 0 0 2 2 2 0 Snf7 MbeB_N PF04837.7 EGC40295.1 - 0.06 13.4 0.2 0.06 13.4 0.2 2.3 3 0 0 3 3 3 0 MbeB-like, N-term conserved region CDC37_N PF03234.9 EGC40295.1 - 0.089 13.1 8.9 0.11 12.7 6.1 1.1 1 0 0 1 1 1 0 Cdc37 N terminal kinase binding Exonuc_VII_L PF02601.10 EGC40295.1 - 0.18 10.9 3.9 0.22 10.6 2.7 1.0 1 0 0 1 1 1 0 Exonuclease VII, large subunit DUF948 PF06103.6 EGC40295.1 - 0.26 11.1 0.1 0.26 11.1 0.1 1.8 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) Osmo_CC PF08946.5 EGC40295.1 - 2.4 8.2 10.0 0.11 12.5 2.7 1.9 2 0 0 2 2 2 0 Osmosensory transporter coiled coil Pkinase_Tyr PF07714.12 EGC40296.1 - 2e-66 223.7 0.0 2.6e-66 223.3 0.0 1.1 1 0 0 1 1 1 1 Protein tyrosine kinase Pkinase PF00069.20 EGC40296.1 - 1.9e-59 200.9 0.0 3.1e-59 200.2 0.0 1.3 1 0 0 1 1 1 1 Protein kinase domain TIG PF01833.19 EGC40296.1 - 4.2e-11 42.6 8.0 4.2e-11 42.6 5.6 2.7 2 1 1 3 3 3 1 IPT/TIG domain APH PF01636.18 EGC40296.1 - 0.027 14.2 0.2 0.071 12.8 0.1 1.6 1 1 1 2 2 2 0 Phosphotransferase enzyme family Kinase-like PF14531.1 EGC40296.1 - 0.11 11.3 0.0 0.18 10.6 0.0 1.2 1 0 0 1 1 1 0 Kinase-like Slu7 PF11708.3 EGC40297.1 - 9e-73 244.9 16.2 9e-73 244.9 11.2 2.5 3 0 0 3 3 3 1 Pre-mRNA splicing Prp18-interacting factor Cob_adeno_trans PF01923.13 EGC40298.1 - 2.1e-47 160.9 0.0 2.4e-47 160.7 0.0 1.0 1 0 0 1 1 1 1 Cobalamin adenosyltransferase CLU PF13236.1 EGC40299.1 - 3.1e-40 137.9 0.0 8.3e-40 136.5 0.0 1.8 1 0 0 1 1 1 1 Clustered mitochondria Ras PF00071.17 EGC40299.1 - 1.6e-21 76.3 0.1 4.8e-16 58.5 0.0 3.1 2 1 1 3 3 3 2 Ras family Miro PF08477.8 EGC40299.1 - 8.5e-09 35.9 0.5 0.0022 18.4 0.0 3.6 2 1 1 3 3 3 2 Miro-like protein TPR_11 PF13414.1 EGC40299.1 - 0.00021 20.8 2.7 0.00049 19.6 0.3 2.3 2 0 0 2 2 2 1 TPR repeat TPR_2 PF07719.12 EGC40299.1 - 0.0023 17.7 1.0 0.11 12.4 0.1 2.6 2 0 0 2 2 2 1 Tetratricopeptide repeat AAA_22 PF13401.1 EGC40299.1 - 0.0083 16.2 0.0 0.21 11.7 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_16 PF13191.1 EGC40299.1 - 0.027 14.4 0.0 0.3 11.0 0.0 2.6 3 0 0 3 3 3 0 AAA ATPase domain TPR_12 PF13424.1 EGC40299.1 - 0.064 13.1 0.3 0.21 11.5 0.1 2.0 2 0 0 2 2 2 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC40299.1 - 0.18 12.5 0.1 0.9 10.3 0.0 2.2 2 1 0 2 2 2 0 Tetratricopeptide repeat Proteasome PF00227.21 EGC40301.1 - 3.8e-58 195.9 0.3 5.8e-58 195.3 0.2 1.3 1 0 0 1 1 1 1 Proteasome subunit Proteasome_A_N PF10584.4 EGC40301.1 - 2.4e-14 52.3 0.1 4e-14 51.5 0.1 1.4 1 0 0 1 1 1 1 Proteasome subunit A N-terminal signature Peptidase_C12 PF01088.16 EGC40302.1 - 3.3e-70 235.6 0.1 4.3e-70 235.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin carboxyl-terminal hydrolase, family 1 DUF3916 PF13079.1 EGC40302.1 - 0.0016 18.1 0.2 0.0031 17.1 0.2 1.5 1 0 0 1 1 1 1 Protein of unknown function (DUF3916) Baculo_11_kDa PF06143.6 EGC40303.1 - 0.013 14.8 0.1 0.053 12.8 0.1 2.0 1 0 0 1 1 1 0 Baculovirus 11 kDa family DUF4083 PF13314.1 EGC40303.1 - 0.11 12.3 6.0 2.3 8.0 0.0 3.0 2 1 0 2 2 2 0 Domain of unknown function (DUF4083) P35 PF02331.10 EGC40303.1 - 0.24 10.4 10.3 0.23 10.5 6.4 1.4 1 1 0 1 1 1 0 Apoptosis preventing protein DUF4446 PF14584.1 EGC40303.1 - 0.65 9.8 12.8 0.46 10.3 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF4446) Ctr PF04145.10 EGC40303.1 - 0.96 9.4 2.6 2.2 8.3 1.8 1.9 1 1 0 1 1 1 0 Ctr copper transporter family Birna_RdRp PF04197.7 EGC40303.1 - 3.7 5.4 12.2 4 5.3 8.5 1.0 1 0 0 1 1 1 0 Birnavirus RNA dependent RNA polymerase (VP1) Methyltransf_10 PF05971.7 EGC40304.1 - 4.2e-05 22.8 0.0 5.9e-05 22.3 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF890) zf-RING_2 PF13639.1 EGC40305.1 - 9.2e-10 38.2 8.8 1.4e-09 37.5 6.1 1.3 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4_3 PF13920.1 EGC40305.1 - 4.1e-08 32.7 7.5 6.7e-08 32.0 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC40305.1 - 1e-07 31.4 11.1 2e-07 30.5 7.7 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC40305.1 - 8.5e-07 28.9 4.1 2e-06 27.8 2.8 1.6 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC40305.1 - 2e-06 27.6 10.9 3.4e-06 26.9 7.6 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40305.1 - 6.6e-05 22.5 9.7 0.00013 21.6 6.7 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_4 PF14570.1 EGC40305.1 - 0.00069 19.1 9.9 0.0012 18.3 6.8 1.4 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC40305.1 - 0.0032 17.2 1.4 0.0076 16.0 0.9 1.5 1 0 0 1 1 1 1 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC40305.1 - 0.0053 16.5 7.0 0.015 15.1 4.8 1.8 1 1 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_6 PF14835.1 EGC40305.1 - 0.056 13.2 3.4 0.12 12.1 2.3 1.5 1 0 0 1 1 1 0 zf-RING of BARD1-type protein Macoilin PF09726.4 EGC40305.1 - 0.13 10.5 41.2 0.19 9.9 28.5 1.2 1 0 0 1 1 1 0 Transmembrane protein Prok-RING_4 PF14447.1 EGC40305.1 - 0.33 10.5 3.5 0.6 9.7 2.4 1.5 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 DUF1272 PF06906.6 EGC40305.1 - 0.51 10.2 5.4 1 9.2 3.7 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) zf-RING_UBOX PF13445.1 EGC40305.1 - 0.62 9.8 5.6 2 8.2 3.9 1.9 1 0 0 1 1 1 0 RING-type zinc-finger DZR PF12773.2 EGC40305.1 - 1.2 8.9 5.6 4 7.3 3.9 1.9 1 1 0 1 1 1 0 Double zinc ribbon AAA PF00004.24 EGC40307.1 - 1.3e-90 300.4 0.0 6.2e-48 162.3 0.0 3.1 2 0 0 2 2 2 2 ATPase family associated with various cellular activities (AAA) AAA_2 PF07724.9 EGC40307.1 - 9.3e-16 58.1 0.0 1.5e-07 31.4 0.0 3.3 3 0 0 3 3 3 2 AAA domain (Cdc48 subfamily) RuvB_N PF05496.7 EGC40307.1 - 6.6e-13 48.2 0.0 2.1e-05 23.7 0.0 3.1 3 0 0 3 3 3 2 Holliday junction DNA helicase ruvB N-terminus AAA_16 PF13191.1 EGC40307.1 - 2.1e-12 47.4 2.9 0.0001 22.3 0.2 3.8 3 2 0 3 3 2 2 AAA ATPase domain AAA_22 PF13401.1 EGC40307.1 - 3.2e-12 46.7 0.3 0.003 17.7 0.0 5.1 3 2 1 4 4 3 2 AAA domain AAA_5 PF07728.9 EGC40307.1 - 1.3e-11 44.3 0.0 0.00033 20.4 0.0 3.6 2 2 0 2 2 2 2 AAA domain (dynein-related subfamily) AAA_17 PF13207.1 EGC40307.1 - 2.9e-11 44.2 0.5 0.00063 20.5 0.0 3.9 3 1 0 3 3 3 2 AAA domain AAA_14 PF13173.1 EGC40307.1 - 1.6e-10 41.0 0.0 0.00087 19.1 0.0 2.9 2 1 0 2 2 2 2 AAA domain AAA_33 PF13671.1 EGC40307.1 - 2.2e-09 37.3 0.7 0.0015 18.4 0.0 3.4 3 1 0 3 3 3 2 AAA domain TIP49 PF06068.8 EGC40307.1 - 3.8e-09 35.7 0.1 0.00033 19.4 0.0 2.4 2 0 0 2 2 2 2 TIP49 C-terminus RNA_helicase PF00910.17 EGC40307.1 - 6.9e-09 35.8 0.0 0.0042 17.2 0.0 3.9 3 0 0 3 3 2 2 RNA helicase Zeta_toxin PF06414.7 EGC40307.1 - 1.7e-08 33.8 0.1 0.00027 20.0 0.0 2.6 2 0 0 2 2 2 2 Zeta toxin NACHT PF05729.7 EGC40307.1 - 3.4e-08 33.3 0.2 0.037 13.6 0.1 4.1 2 2 1 4 4 4 2 NACHT domain ABC_tran PF00005.22 EGC40307.1 - 4.2e-08 33.5 5.6 0.0055 17.0 0.0 3.8 3 1 0 3 3 3 2 ABC transporter IstB_IS21 PF01695.12 EGC40307.1 - 1.1e-07 31.4 0.3 0.0094 15.3 0.0 2.5 2 0 0 2 2 2 2 IstB-like ATP binding protein Mg_chelatase PF01078.16 EGC40307.1 - 3e-07 29.7 0.3 0.012 14.8 0.0 2.4 2 0 0 2 2 2 2 Magnesium chelatase, subunit ChlI AAA_19 PF13245.1 EGC40307.1 - 3.3e-07 29.9 0.1 0.0083 15.8 0.0 2.7 2 0 0 2 2 2 2 Part of AAA domain Arch_ATPase PF01637.13 EGC40307.1 - 3.2e-06 27.0 1.5 0.34 10.5 0.0 4.4 4 1 1 5 5 5 2 Archaeal ATPase AAA_28 PF13521.1 EGC40307.1 - 7.3e-06 26.0 0.0 0.18 11.7 0.0 2.6 2 0 0 2 2 2 2 AAA domain Sigma54_activat PF00158.21 EGC40307.1 - 1.3e-05 24.7 0.0 0.1 12.1 0.0 2.9 3 0 0 3 3 2 2 Sigma-54 interaction domain NB-ARC PF00931.17 EGC40307.1 - 3.1e-05 22.9 0.1 0.1 11.4 0.0 2.6 2 0 0 2 2 2 2 NB-ARC domain Viral_helicase1 PF01443.13 EGC40307.1 - 5.9e-05 22.7 0.0 0.11 12.0 0.0 2.6 2 0 0 2 2 2 2 Viral (Superfamily 1) RNA helicase AAA_25 PF13481.1 EGC40307.1 - 8.6e-05 22.0 5.1 2.4 7.4 0.1 4.3 2 2 2 4 4 4 2 AAA domain Vps4_C PF09336.5 EGC40307.1 - 0.0001 22.1 0.4 0.1 12.5 0.0 3.0 3 0 0 3 3 2 1 Vps4 C terminal oligomerisation domain KaiC PF06745.8 EGC40307.1 - 0.00015 20.9 0.4 1.4 7.9 0.0 3.4 2 1 1 3 3 3 1 KaiC PhoH PF02562.11 EGC40307.1 - 0.00021 20.6 0.1 0.66 9.1 0.0 2.8 3 0 0 3 3 2 2 PhoH-like protein AAA_24 PF13479.1 EGC40307.1 - 0.00042 19.9 0.0 0.16 11.5 0.0 2.7 2 0 0 2 2 2 1 AAA domain AAA_3 PF07726.6 EGC40307.1 - 0.00053 19.6 0.0 0.4 10.2 0.0 2.6 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) NTPase_1 PF03266.10 EGC40307.1 - 0.00053 19.7 0.6 0.47 10.1 0.0 3.9 2 1 1 3 3 3 1 NTPase UPF0079 PF02367.12 EGC40307.1 - 0.00066 19.2 0.0 0.88 9.2 0.0 2.4 2 0 0 2 2 2 2 Uncharacterised P-loop hydrolase UPF0079 Bac_DnaA PF00308.13 EGC40307.1 - 0.0007 19.3 0.0 0.5 9.9 0.0 3.2 3 0 0 3 3 3 1 Bacterial dnaA protein AAA_18 PF13238.1 EGC40307.1 - 0.00076 19.7 16.6 0.17 12.1 0.2 4.7 4 2 0 4 4 4 2 AAA domain DUF815 PF05673.8 EGC40307.1 - 0.0017 17.3 0.0 0.49 9.2 0.0 2.7 2 0 0 2 2 2 1 Protein of unknown function (DUF815) Cytidylate_kin2 PF13189.1 EGC40307.1 - 0.0017 18.2 0.1 4.1 7.2 0.1 3.3 2 1 0 2 2 2 0 Cytidylate kinase-like family SKI PF01202.17 EGC40307.1 - 0.0018 18.1 1.3 0.95 9.3 0.0 3.0 3 0 0 3 3 2 1 Shikimate kinase PduV-EutP PF10662.4 EGC40307.1 - 0.0026 17.2 0.0 1.2 8.5 0.0 2.5 2 0 0 2 2 2 1 Ethanolamine utilisation - propanediol utilisation Sigma54_activ_2 PF14532.1 EGC40307.1 - 0.0031 17.5 0.0 1.6 8.7 0.0 2.7 2 0 0 2 2 2 1 Sigma-54 interaction domain AAA_10 PF12846.2 EGC40307.1 - 0.0063 15.9 0.2 3 7.1 0.0 3.6 3 1 1 4 4 4 1 AAA-like domain T2SE PF00437.15 EGC40307.1 - 0.038 12.9 0.0 4 6.2 0.0 2.6 2 1 0 2 2 2 0 Type II/IV secretion system protein CPT PF07931.7 EGC40307.1 - 0.094 12.3 0.0 3.4 7.2 0.0 2.5 2 0 0 2 2 2 0 Chloramphenicol phosphotransferase-like protein AFG1_ATPase PF03969.11 EGC40307.1 - 0.29 9.9 1.8 3.7 6.2 0.0 2.9 3 0 0 3 3 3 0 AFG1-like ATPase Amelogenin PF02948.10 EGC40307.1 - 0.59 10.7 5.2 0.37 11.3 2.1 1.7 1 1 0 1 1 1 0 Amelogenin FNIP PF05725.7 EGC40308.1 - 2.5e-67 222.6 59.8 3.8e-13 49.1 2.5 8.0 3 2 5 9 9 9 9 FNIP Repeat DUF1769 PF08588.5 EGC40308.1 - 1.6e-05 24.7 11.0 2.1 8.3 0.0 7.1 5 4 3 8 8 8 3 Protein of unknown function (DUF1769) Phage_min_tail PF05939.8 EGC40308.1 - 0.0018 18.1 0.0 28 4.6 0.0 4.6 3 1 2 5 5 5 1 Phage minor tail protein LRR_5 PF13306.1 EGC40308.1 - 0.014 15.1 12.1 0.09 12.4 3.8 3.3 1 1 2 3 3 3 0 Leucine rich repeats (6 copies) LRR_8 PF13855.1 EGC40308.1 - 1.2 8.9 4.6 4 7.2 1.8 2.8 2 1 0 2 2 2 0 Leucine rich repeat Pkinase PF00069.20 EGC40309.1 - 1e-50 172.3 2.6 1.1e-50 172.1 1.8 1.0 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40309.1 - 4e-32 111.3 0.3 4.7e-32 111.0 0.2 1.0 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC40309.1 - 6.5e-05 22.0 0.0 8.3e-05 21.6 0.0 1.2 1 0 0 1 1 1 1 Kinase-like APH PF01636.18 EGC40309.1 - 0.0027 17.4 0.0 0.0039 16.9 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family Seadorna_VP7 PF07387.6 EGC40309.1 - 0.0035 16.2 0.1 0.0065 15.3 0.1 1.4 1 1 0 1 1 1 1 Seadornavirus VP7 OTU PF02338.14 EGC40310.1 - 2.8e-15 56.9 0.2 6.1e-15 55.8 0.1 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease PAT1 PF09770.4 EGC40310.1 - 0.86 7.7 11.6 1 7.4 8.0 1.1 1 0 0 1 1 1 0 Topoisomerase II-associated protein PAT1 OTU PF02338.14 EGC40311.1 - 3.2e-15 56.7 0.4 6.8e-15 55.7 0.1 1.6 2 0 0 2 2 2 1 OTU-like cysteine protease DUF4044 PF13253.1 EGC40313.1 - 0.074 12.2 0.4 0.12 11.5 0.3 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF4044) FNIP PF05725.7 EGC40314.1 - 4.9e-93 304.8 67.2 3.7e-12 46.0 0.2 12.7 6 4 6 15 15 15 13 FNIP Repeat ACDC PF14733.1 EGC40314.1 - 0.073 13.2 0.1 26 5.0 0.0 3.8 3 0 0 3 3 3 0 AP2-coincident C-terminal Ins134_P3_kin PF05770.6 EGC40315.1 - 8.1e-56 189.2 2.9 9.5e-56 189.0 2.0 1.0 1 0 0 1 1 1 1 Inositol 1, 3, 4-trisphosphate 5/6-kinase ATP-grasp_3 PF02655.9 EGC40315.1 - 1.6e-05 24.7 0.1 4.6e-05 23.3 0.1 1.7 1 1 0 1 1 1 1 ATP-grasp domain ATP-grasp_4 PF13535.1 EGC40315.1 - 5.7e-05 22.9 0.0 0.00026 20.7 0.0 1.9 1 1 0 1 1 1 1 ATP-grasp domain C1_3 PF07649.7 EGC40316.1 - 0.91 9.6 10.7 0.11 12.5 1.2 2.7 2 0 0 2 2 2 0 C1-like domain Defensin_beta PF00711.14 EGC40316.1 - 1.1 9.2 4.9 2.1 8.3 0.3 2.5 2 0 0 2 2 2 0 Beta defensin FNIP PF05725.7 EGC40318.1 - 4.4e-73 241.0 47.3 1.9e-14 53.3 2.1 6.1 2 1 6 8 8 8 8 FNIP Repeat NUC153 PF08159.7 EGC40320.1 - 1.1e-08 34.5 0.2 3e-07 29.9 0.0 3.0 2 0 0 2 2 2 1 NUC153 domain OB_NTP_bind PF07717.11 EGC40321.1 - 1.3e-24 86.1 0.2 1.3e-24 86.1 0.2 2.0 3 0 0 3 3 3 1 Oligonucleotide/oligosaccharide-binding (OB)-fold HA2 PF04408.18 EGC40321.1 - 7e-23 80.5 0.0 1.3e-22 79.6 0.0 1.5 1 0 0 1 1 1 1 Helicase associated domain (HA2) Helicase_C PF00271.26 EGC40321.1 - 2.3e-13 49.8 0.0 4.5e-13 48.8 0.0 1.5 1 0 0 1 1 1 1 Helicase conserved C-terminal domain NAF PF03822.9 EGC40321.1 - 0.089 12.5 0.0 0.69 9.6 0.0 2.4 2 0 0 2 2 2 0 NAF domain Ubiq_cyt_C_chap PF03981.7 EGC40322.1 - 3.2e-30 104.8 0.1 4.5e-30 104.3 0.1 1.2 1 0 0 1 1 1 1 Ubiquinol-cytochrome C chaperone DUF4119 PF13494.1 EGC40322.1 - 0.33 10.9 0.1 0.33 10.9 0.1 2.4 2 1 0 2 2 2 0 Domain of unknown function, B. Theta Gene description (DUF4119) Atg14 PF10186.4 EGC40323.1 - 0.001 18.0 2.8 0.0015 17.5 1.9 1.1 1 0 0 1 1 1 1 UV radiation resistance protein and autophagy-related subunit 14 ARA70 PF12489.3 EGC40323.1 - 0.0016 18.4 1.4 0.0029 17.5 1.0 1.4 1 0 0 1 1 1 1 Nuclear coactivator DUF489 PF04356.7 EGC40323.1 - 0.0097 15.5 2.8 0.036 13.6 1.9 1.8 1 1 1 2 2 2 1 Protein of unknown function (DUF489) TMF_DNA_bd PF12329.3 EGC40323.1 - 0.022 14.5 6.0 0.051 13.3 4.2 1.6 1 0 0 1 1 1 0 TATA element modulatory factor 1 DNA binding CemA PF03040.9 EGC40323.1 - 0.052 13.1 0.6 0.11 12.0 0.1 1.7 2 0 0 2 2 2 0 CemA family Colicin PF01024.14 EGC40323.1 - 0.074 12.6 1.8 0.1 12.1 0.7 1.6 1 1 1 2 2 2 0 Colicin pore forming domain DUF641 PF04859.7 EGC40323.1 - 0.096 12.4 1.6 0.14 11.8 0.6 1.5 1 1 0 1 1 1 0 Plant protein of unknown function (DUF641) Prefoldin_3 PF13758.1 EGC40323.1 - 0.18 11.5 5.9 1.7 8.4 0.3 2.3 1 1 1 2 2 2 0 Prefoldin subunit FCH PF00611.18 EGC40323.1 - 0.26 11.5 2.9 0.7 10.1 0.1 2.4 2 1 1 3 3 3 0 Fes/CIP4, and EFC/F-BAR homology domain Transposase_24 PF03004.9 EGC40323.1 - 0.33 10.8 3.6 0.25 11.2 0.6 2.1 2 1 0 2 2 2 0 Plant transposase (Ptta/En/Spm family) DUF4033 PF13225.1 EGC40325.1 - 0.027 14.0 0.5 0.085 12.4 0.4 1.8 1 0 0 1 1 1 0 Domain of unknown function (DUF4033) APH PF01636.18 EGC40325.1 - 1.6 8.4 0.0 2.6 7.6 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family FNIP PF05725.7 EGC40326.1 - 6.4e-45 150.8 29.9 1.3e-13 50.5 0.5 5.7 4 2 2 7 7 7 5 FNIP Repeat DUF1769 PF08588.5 EGC40326.1 - 0.002 18.0 5.3 3.6 7.5 0.0 4.7 3 1 1 4 4 4 3 Protein of unknown function (DUF1769) rpo30_N PF12410.3 EGC40326.1 - 0.043 13.4 0.1 0.067 12.8 0.1 1.3 1 0 0 1 1 1 0 Poxvirus DNA dependent RNA polymerase 30kDa subunit DUF4321 PF14209.1 EGC40326.1 - 6.4 6.5 8.0 3.5 7.4 0.4 3.3 3 0 0 3 3 3 0 Domain of unknown function (DUF4321) VPS9 PF02204.13 EGC40327.1 - 4.5e-14 52.3 0.8 4.5e-14 52.3 0.6 2.7 2 0 0 2 2 2 1 Vacuolar sorting protein 9 (VPS9) domain Ank_2 PF12796.2 EGC40327.1 - 6.2e-12 45.6 6.7 1.5e-05 25.2 0.0 4.7 3 2 1 4 4 4 3 Ankyrin repeats (3 copies) Ank_3 PF13606.1 EGC40327.1 - 2.7e-08 33.2 1.2 5.5 7.5 0.0 6.7 6 0 0 6 6 6 3 Ankyrin repeat Ank_4 PF13637.1 EGC40327.1 - 7.2e-07 29.5 0.4 6.1 7.4 0.0 5.7 4 1 3 7 7 7 2 Ankyrin repeats (many copies) Ank PF00023.25 EGC40327.1 - 1.7e-06 27.5 1.5 0.91 9.4 0.0 5.7 6 0 0 6 6 6 1 Ankyrin repeat Ank_5 PF13857.1 EGC40327.1 - 0.0072 16.5 8.0 0.039 14.1 0.0 4.3 3 1 0 4 4 4 1 Ankyrin repeats (many copies) DUF2151 PF10221.4 EGC40328.1 - 1.6 6.7 5.5 2.3 6.3 3.8 1.1 1 0 0 1 1 1 0 Cell cycle and development regulator Tfb4 PF03850.9 EGC40332.1 - 1.1e-86 290.5 12.2 1.2e-86 290.3 8.5 1.0 1 0 0 1 1 1 1 Transcription factor Tfb4 zf-AN1 PF01428.11 EGC40332.1 - 1.1 9.1 8.3 0.45 10.4 1.6 2.3 1 1 1 2 2 2 0 AN1-like Zinc finger DUF2477 PF10631.4 EGC40332.1 - 9.5 6.4 9.5 43 4.3 6.6 2.0 1 1 0 1 1 1 0 Protein of unknown function (DUF2477) PP2C PF00481.16 EGC40334.1 - 4e-54 183.7 0.0 8.3e-54 182.6 0.0 1.6 1 0 0 1 1 1 1 Protein phosphatase 2C LRR_4 PF12799.2 EGC40334.1 - 9.2e-40 133.6 74.9 1e-06 28.1 1.5 11.5 7 3 6 13 13 13 12 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC40334.1 - 2.4e-39 132.8 56.1 3.9e-08 32.9 1.1 9.8 6 2 5 11 11 11 10 Leucine rich repeat LRR_1 PF00560.28 EGC40334.1 - 7e-30 98.4 62.0 0.0028 17.4 0.4 17.5 18 0 0 18 18 18 10 Leucine Rich Repeat LRR_7 PF13504.1 EGC40334.1 - 3.7e-20 68.4 42.9 0.12 12.6 0.3 16.3 16 0 0 16 16 16 7 Leucine rich repeat PP2C_2 PF13672.1 EGC40334.1 - 4.8e-05 22.8 1.3 6.8e-05 22.3 0.0 1.9 2 0 0 2 2 2 1 Protein phosphatase 2C LRR_6 PF13516.1 EGC40334.1 - 0.00096 18.9 67.9 0.029 14.4 1.2 15.0 16 2 2 18 18 18 4 Leucine Rich repeat LRR_9 PF14580.1 EGC40334.1 - 0.0081 15.7 6.9 0.84 9.1 0.0 4.5 2 1 3 5 5 5 3 Leucine-rich repeat CTP_transf_1 PF01148.15 EGC40335.1 - 7e-62 209.4 27.6 9.6e-62 208.9 19.1 1.2 1 0 0 1 1 1 1 Cytidylyltransferase family Acetyltransf_1 PF00583.19 EGC40336.1 - 1.3e-15 57.1 0.1 2e-15 56.5 0.1 1.3 1 0 0 1 1 1 1 Acetyltransferase (GNAT) family Acetyltransf_4 PF13420.1 EGC40336.1 - 3.3e-11 43.3 3.4 3.9e-11 43.1 2.4 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_7 PF13508.1 EGC40336.1 - 3.4e-11 43.1 0.4 7.9e-11 41.9 0.2 1.7 1 1 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_3 PF13302.1 EGC40336.1 - 3.4e-09 37.0 0.3 4e-09 36.7 0.2 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_10 PF13673.1 EGC40336.1 - 4.6e-06 26.7 0.0 5.6e-06 26.4 0.0 1.2 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_8 PF13523.1 EGC40336.1 - 1.7e-05 24.7 0.0 2e-05 24.5 0.0 1.1 1 0 0 1 1 1 1 Acetyltransferase (GNAT) domain Acetyltransf_CG PF14542.1 EGC40336.1 - 0.0012 18.6 0.1 0.0032 17.3 0.0 1.7 2 0 0 2 2 2 1 GCN5-related N-acetyl-transferase FR47 PF08445.5 EGC40336.1 - 0.0052 16.5 0.0 0.0088 15.7 0.0 1.4 1 0 0 1 1 1 1 FR47-like protein TM2 PF05154.11 EGC40337.1 - 2e-06 27.9 4.0 3.1e-06 27.3 2.8 1.3 1 0 0 1 1 1 1 TM2 domain DUF3169 PF11368.3 EGC40337.1 - 0.035 13.3 0.0 0.038 13.2 0.0 1.0 1 0 0 1 1 1 0 Protein of unknown function (DUF3169) Stomoxyn PF11585.3 EGC40337.1 - 0.12 12.1 0.7 0.18 11.6 0.5 1.2 1 0 0 1 1 1 0 Insect antimicrobial peptide, stomoxyn TM2 PF05154.11 EGC40338.1 - 1.5e-11 44.2 6.3 2.4e-11 43.6 4.4 1.3 1 0 0 1 1 1 1 TM2 domain ATG22 PF11700.3 EGC40338.1 - 0.00027 19.5 0.0 0.00038 19.0 0.0 1.1 1 0 0 1 1 1 1 Vacuole effluxer Atg22 like Hemerythrin PF01814.18 EGC40339.1 - 3.6e-12 46.5 0.7 5.5e-12 45.9 0.5 1.3 1 0 0 1 1 1 1 Hemerythrin HHE cation binding domain Fib_alpha PF08702.5 EGC40339.1 - 0.037 14.1 0.1 0.086 12.9 0.1 1.5 1 0 0 1 1 1 0 Fibrinogen alpha/beta chain family FXa_inhibition PF14670.1 EGC40341.1 - 0.13 12.3 1.4 0.25 11.5 0.9 1.4 1 0 0 1 1 1 0 Coagulation Factor Xa inhibitory site Kinesin PF00225.18 EGC40342.1 - 0.072 11.7 0.0 0.076 11.6 0.0 1.1 1 0 0 1 1 1 0 Kinesin motor domain Ank_2 PF12796.2 EGC40343.1 - 3.7e-19 68.8 8.4 9.4e-15 54.7 1.3 2.4 1 1 1 2 2 2 2 Ankyrin repeats (3 copies) Ank PF00023.25 EGC40343.1 - 9.8e-18 62.9 1.3 1.9e-06 27.4 0.0 4.5 4 0 0 4 4 4 3 Ankyrin repeat Ank_5 PF13857.1 EGC40343.1 - 3.9e-14 52.3 3.9 6.1e-10 39.0 0.8 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_4 PF13637.1 EGC40343.1 - 1.2e-12 48.0 2.2 2.6e-06 27.8 0.0 3.5 2 1 1 3 3 3 3 Ankyrin repeats (many copies) Ank_3 PF13606.1 EGC40343.1 - 1.2e-12 46.7 5.9 0.0002 21.2 0.0 4.6 4 1 0 4 4 4 4 Ankyrin repeat Abi_C PF14355.1 EGC40343.1 - 0.91 9.5 5.0 1.7 8.6 0.1 3.0 3 1 0 3 3 3 0 Abortive infection C-terminus DUF3447 PF11929.3 EGC40343.1 - 0.97 9.2 6.4 0.36 10.6 0.3 2.9 2 1 1 3 3 3 0 Domain of unknown function (DUF3447) DUF964 PF06133.6 EGC40343.1 - 3.3 7.7 14.0 17 5.4 0.4 2.8 1 1 2 3 3 3 0 Protein of unknown function (DUF964) DUF2462 PF09495.5 EGC40344.1 - 9.3e-05 23.0 21.2 0.00019 22.0 14.7 1.6 1 1 0 1 1 1 1 Protein of unknown function (DUF2462) DUF4047 PF13256.1 EGC40344.1 - 0.014 15.3 1.7 0.017 15.0 1.2 1.3 1 0 0 1 1 1 0 Domain of unknown function (DUF4047) Tox-URI2 PF15653.1 EGC40344.1 - 1.4 9.1 7.9 1 9.6 3.5 1.9 1 1 1 2 2 2 0 URI fold toxin 2 WBS_methylT PF12589.3 EGC40345.1 - 2.8e-20 72.6 10.3 4.5e-20 71.9 7.2 1.3 1 0 0 1 1 1 1 Methyltransferase involved in Williams-Beuren syndrome Methyltransf_11 PF08241.7 EGC40345.1 - 1.1e-10 41.8 0.0 2e-10 40.9 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC40345.1 - 1.5e-06 28.4 0.0 3.1e-06 27.4 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC40345.1 - 2.3e-05 24.1 0.0 3.4e-05 23.6 0.0 1.2 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC40345.1 - 0.00015 21.4 0.0 0.00028 20.5 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC40345.1 - 0.00034 21.0 0.0 0.001 19.4 0.0 1.9 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40345.1 - 0.00091 19.7 0.0 0.0014 19.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC40345.1 - 0.0023 17.9 0.0 0.0047 16.9 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain N6_N4_Mtase PF01555.13 EGC40345.1 - 0.0033 16.9 0.3 0.21 11.0 0.0 2.2 2 0 0 2 2 2 1 DNA methylase AdoMet_MTase PF07757.8 EGC40345.1 - 0.013 15.6 0.4 0.048 13.7 0.0 2.1 2 0 0 2 2 2 0 Predicted AdoMet-dependent methyltransferase Ras PF00071.17 EGC40346.1 - 3.4e-43 146.8 2.4 2.4e-23 82.2 0.2 2.4 2 0 0 2 2 2 2 Ras family Miro PF08477.8 EGC40346.1 - 3.9e-15 56.3 0.7 8.4e-10 39.1 0.1 2.9 2 0 0 2 2 2 2 Miro-like protein PH PF00169.24 EGC40346.1 - 1.7e-08 34.5 4.4 5.3e-08 32.9 3.1 1.9 1 0 0 1 1 1 1 PH domain Arf PF00025.16 EGC40346.1 - 1.5e-05 24.3 3.6 0.0022 17.2 0.2 2.9 3 0 0 3 3 3 2 ADP-ribosylation factor family PH_11 PF15413.1 EGC40346.1 - 0.01 16.1 7.7 0.011 16.0 3.1 2.9 2 1 0 2 2 2 0 Pleckstrin homology domain Tctex-1 PF03645.8 EGC40346.1 - 0.072 12.9 3.6 2.6 7.9 0.1 3.5 3 1 0 3 3 3 0 Tctex-1 family Kua-UEV1_localn PF10520.4 EGC40347.1 - 8e-72 240.6 4.3 1.5e-71 239.7 2.9 1.4 1 0 0 1 1 1 1 Kua-ubiquitin conjugating enzyme hybrid localisation domain Folate_carrier PF01770.13 EGC40347.1 - 0.0087 14.6 2.2 0.016 13.7 1.6 1.4 1 0 0 1 1 1 1 Reduced folate carrier Ctr PF04145.10 EGC40347.1 - 0.009 16.0 0.1 0.017 15.1 0.1 1.4 1 0 0 1 1 1 1 Ctr copper transporter family DUF2370 PF10176.4 EGC40347.1 - 0.011 15.1 1.9 0.018 14.4 1.3 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2370) DUF4191 PF13829.1 EGC40347.1 - 0.023 13.8 0.1 0.044 12.8 0.1 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF4191) AIF_C PF14721.1 EGC40347.1 - 0.023 14.9 2.9 0.039 14.2 2.0 1.3 1 0 0 1 1 1 0 Apoptosis-inducing factor, mitochondrion-associated, C-term DUF106 PF01956.11 EGC40347.1 - 0.025 14.1 0.8 0.057 12.9 0.6 1.5 1 0 0 1 1 1 0 Integral membrane protein DUF106 DUF853 PF05872.7 EGC40347.1 - 0.33 9.2 2.3 0.45 8.8 1.6 1.1 1 0 0 1 1 1 0 Bacterial protein of unknown function (DUF853) Presenilin PF01080.12 EGC40347.1 - 0.71 8.6 4.9 0.18 10.5 0.9 1.7 1 1 1 2 2 2 0 Presenilin IncA PF04156.9 EGC40347.1 - 2.5 7.6 7.2 3.8 7.0 5.0 1.3 1 0 0 1 1 1 0 IncA protein WD40 PF00400.27 EGC40348.1 - 8.4e-65 212.5 28.3 1.9e-10 40.2 0.9 7.1 7 0 0 7 7 7 7 WD domain, G-beta repeat IKI3 PF04762.7 EGC40348.1 - 3.1e-05 22.0 7.8 0.014 13.2 0.3 3.4 2 2 1 3 3 3 3 IKI3 family Nucleoporin_N PF08801.6 EGC40348.1 - 0.0012 17.6 4.9 0.75 8.4 0.0 3.6 1 1 3 4 4 4 2 Nup133 N terminal like Legionella_OMP PF05150.7 EGC40348.1 - 1.3 8.0 6.9 0.26 10.3 2.1 1.8 2 1 0 2 2 2 0 Legionella pneumophila major outer membrane protein precursor ABC_membrane PF00664.18 EGC40349.1 - 5.8e-24 84.9 17.9 1.1e-23 84.0 12.4 1.5 1 0 0 1 1 1 1 ABC transporter transmembrane region ABC_tran PF00005.22 EGC40349.1 - 2.1e-13 50.7 0.0 4.5e-13 49.6 0.0 1.6 1 0 0 1 1 1 1 ABC transporter DUF1693 PF07984.7 EGC40350.1 - 1.7e-17 63.5 0.8 2.1e-08 33.6 0.0 3.2 3 0 0 3 3 3 3 Domain of unknown function (DUF1693) Peptidase_C39_2 PF13529.1 EGC40351.1 - 1.7e-17 64.0 0.0 3.8e-17 63.0 0.0 1.6 1 0 0 1 1 1 1 Peptidase_C39 like family Peptidase_C39 PF03412.10 EGC40351.1 - 4.3e-08 33.0 0.0 0.00022 21.0 0.0 2.3 2 0 0 2 2 2 2 Peptidase C39 family Guanylate_cyc_2 PF09778.4 EGC40351.1 - 1e-05 24.8 0.1 0.051 12.7 0.0 2.5 3 0 0 3 3 3 2 Guanylylate cyclase DUF3335 PF11814.3 EGC40351.1 - 1.7e-05 24.0 0.0 0.012 14.8 0.0 2.2 2 0 0 2 2 2 2 Peptidase_C39 like family Peptidase_C70 PF12385.3 EGC40351.1 - 4.2e-05 23.3 0.1 0.0011 18.6 0.0 2.2 1 1 0 2 2 2 1 Papain-like cysteine protease AvrRpt2 Transpep_BrtH PF14399.1 EGC40351.1 - 7.4e-05 22.1 0.0 0.0002 20.7 0.0 1.7 1 1 0 1 1 1 1 NlpC/p60-like transpeptidase Phytochelatin PF05023.9 EGC40351.1 - 0.073 12.0 0.0 6.7 5.6 0.0 2.7 3 0 0 3 3 3 0 Phytochelatin synthase p450 PF00067.17 EGC40353.1 - 2.1e-80 270.4 0.2 2.4e-80 270.3 0.1 1.0 1 0 0 1 1 1 1 Cytochrome P450 Chordopox_G3 PF06129.7 EGC40353.1 - 0.55 10.4 4.0 5.1 7.2 0.6 3.2 3 0 0 3 3 3 0 Chordopoxvirus G3 protein FNIP PF05725.7 EGC40355.1 - 1.4e-11 44.1 20.6 3.9e-06 26.7 0.2 6.8 3 2 2 5 5 5 4 FNIP Repeat F5_F8_type_C PF00754.20 EGC40356.1 - 7.5e-27 93.7 1.4 1.1e-26 93.1 0.9 1.3 1 0 0 1 1 1 1 F5/8 type C domain H_lectin PF09458.5 EGC40356.1 - 2.2e-21 75.3 0.5 7.2e-21 73.6 0.4 1.9 2 0 0 2 2 2 1 H-type lectin domain 3H PF02829.9 EGC40357.1 - 0.67 10.0 11.0 0.064 13.2 3.2 2.5 2 1 0 2 2 2 0 3H domain Tweety PF04906.8 EGC40359.1 - 6.8e-12 44.5 1.5 2e-09 36.4 0.7 2.4 2 0 0 2 2 2 2 Tweety Sarcoglycan_2 PF05510.8 EGC40359.1 - 0.0014 17.0 0.2 0.0078 14.5 0.0 2.2 2 1 1 3 3 3 1 Sarcoglycan alpha/epsilon Tetraspannin PF00335.15 EGC40359.1 - 0.0027 17.0 12.7 0.0053 16.0 0.1 3.4 3 1 0 3 3 3 1 Tetraspanin family Prominin PF05478.6 EGC40359.1 - 0.0077 13.8 8.0 0.011 13.2 0.1 2.5 3 0 0 3 3 3 2 Prominin EphA2_TM PF14575.1 EGC40359.1 - 0.014 15.7 0.1 3.2 8.1 0.0 3.5 4 0 0 4 4 4 0 Ephrin type-A receptor 2 transmembrane domain DUF1634 PF07843.6 EGC40359.1 - 0.051 13.1 6.6 0.095 12.3 1.5 3.1 2 1 1 3 3 3 0 Protein of unknown function (DUF1634) Pex24p PF06398.6 EGC40359.1 - 0.052 12.3 7.9 0.31 9.8 2.8 3.2 2 1 1 3 3 3 0 Integral peroxisomal membrane peroxin TMEM154 PF15102.1 EGC40359.1 - 0.074 12.7 2.7 0.25 11.0 0.1 2.8 2 1 1 3 3 3 0 TMEM154 protein family DUF4131 PF13567.1 EGC40359.1 - 0.38 10.1 3.1 2.6 7.4 0.0 2.2 2 0 0 2 2 2 0 Domain of unknown function (DUF4131) Prenyltrans PF00432.16 EGC40360.1 - 4.6e-39 131.6 2.0 2e-09 36.8 0.0 6.2 6 0 0 6 6 6 5 Prenyltransferase and squalene oxidase repeat Prenyltrans_1 PF13243.1 EGC40360.1 - 4.1e-32 110.4 0.0 8e-14 51.5 0.0 5.9 4 2 2 6 6 6 5 Prenyltransferase-like Prenyltrans_2 PF13249.1 EGC40360.1 - 4.7e-29 101.0 0.0 7.4e-14 52.1 0.0 5.2 3 2 2 5 5 5 5 Prenyltransferase-like Pec_lyase PF09492.5 EGC40360.1 - 8.8e-08 31.6 1.1 0.1 11.7 0.0 5.0 5 1 0 5 5 5 3 Pectic acid lyase A2M_comp PF07678.9 EGC40360.1 - 0.00014 21.1 1.6 1.6 7.9 0.0 5.3 5 2 1 6 6 6 1 A-macroglobulin complement component Mago-bind PF09282.5 EGC40360.1 - 0.016 14.7 0.1 0.41 10.2 0.0 2.4 2 0 0 2 2 2 0 Mago binding Chromo PF00385.19 EGC40361.1 - 9.5e-07 28.4 0.6 1.2e-06 28.1 0.4 1.1 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Chromo_shadow PF01393.14 EGC40361.1 - 0.061 13.1 0.1 0.066 13.0 0.0 1.2 1 0 0 1 1 1 0 Chromo shadow domain Pkinase PF00069.20 EGC40362.1 - 2.6e-68 230.0 0.0 1.1e-67 227.9 0.0 2.1 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40362.1 - 2.2e-47 161.3 0.0 4.7e-47 160.2 0.0 1.5 1 0 0 1 1 1 1 Protein tyrosine kinase PBD PF00786.23 EGC40362.1 - 2.6e-16 59.7 0.4 2.6e-16 59.7 0.3 4.1 3 0 0 3 3 3 1 P21-Rho-binding domain Kinase-like PF14531.1 EGC40362.1 - 0.00012 21.1 0.0 0.0011 17.9 0.0 2.1 1 1 1 2 2 2 1 Kinase-like Pox_TAA1 PF03295.9 EGC40362.1 - 0.034 13.7 0.1 0.27 10.9 0.0 2.2 2 0 0 2 2 2 0 Poxvirus trans-activator protein A1 C-terminal ABC2_membrane PF01061.19 EGC40363.1 - 2.1e-35 121.8 19.8 2.1e-35 121.8 13.7 1.9 2 0 0 2 2 2 1 ABC-2 type transporter ABC_tran PF00005.22 EGC40363.1 - 6.6e-27 94.4 0.0 1.6e-26 93.2 0.0 1.7 1 0 0 1 1 1 1 ABC transporter AAA_21 PF13304.1 EGC40363.1 - 2.4e-13 50.7 0.0 6.3e-13 49.3 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_25 PF13481.1 EGC40363.1 - 1.3e-05 24.6 0.0 0.0055 16.1 0.0 2.4 2 0 0 2 2 2 1 AAA domain AAA_15 PF13175.1 EGC40363.1 - 1.5e-05 24.2 1.1 0.0062 15.6 0.0 2.6 3 0 0 3 3 3 2 AAA ATPase domain AAA_22 PF13401.1 EGC40363.1 - 1.9e-05 24.8 0.0 6.4e-05 23.0 0.0 1.8 1 1 0 1 1 1 1 AAA domain AAA_17 PF13207.1 EGC40363.1 - 0.00012 22.8 0.0 0.00027 21.7 0.0 1.6 1 0 0 1 1 1 1 AAA domain SMC_N PF02463.14 EGC40363.1 - 0.00047 19.4 0.1 0.18 11.0 0.0 2.3 2 0 0 2 2 2 2 RecF/RecN/SMC N terminal domain AAA_16 PF13191.1 EGC40363.1 - 0.00063 19.7 0.0 0.0011 18.9 0.0 1.4 1 1 0 1 1 1 1 AAA ATPase domain AAA_18 PF13238.1 EGC40363.1 - 0.00093 19.5 0.0 0.0025 18.1 0.0 1.8 1 0 0 1 1 1 1 AAA domain Arch_ATPase PF01637.13 EGC40363.1 - 0.0012 18.6 0.0 0.0023 17.6 0.0 1.4 1 0 0 1 1 1 1 Archaeal ATPase AAA_29 PF13555.1 EGC40363.1 - 0.0023 17.4 0.4 0.0059 16.1 0.2 1.8 2 0 0 2 2 1 1 P-loop containing region of AAA domain DUF258 PF03193.11 EGC40363.1 - 0.0026 16.9 0.1 0.0049 16.0 0.0 1.4 1 0 0 1 1 1 1 Protein of unknown function, DUF258 SbcCD_C PF13558.1 EGC40363.1 - 0.0035 17.2 0.1 0.022 14.6 0.1 2.3 1 1 0 1 1 1 1 Putative exonuclease SbcCD, C subunit AAA PF00004.24 EGC40363.1 - 0.0038 17.4 0.0 0.22 11.7 0.0 2.4 2 0 0 2 2 2 1 ATPase family associated with various cellular activities (AAA) cobW PF02492.14 EGC40363.1 - 0.0043 16.5 0.0 0.0071 15.7 0.0 1.4 1 0 0 1 1 1 1 CobW/HypB/UreG, nucleotide-binding domain T2SE PF00437.15 EGC40363.1 - 0.0062 15.4 0.1 0.011 14.6 0.1 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_23 PF13476.1 EGC40363.1 - 0.0096 16.2 0.0 0.029 14.7 0.0 1.8 1 0 0 1 1 1 1 AAA domain AAA_33 PF13671.1 EGC40363.1 - 0.01 15.7 0.0 0.022 14.6 0.0 1.7 1 1 0 1 1 1 1 AAA domain AAA_10 PF12846.2 EGC40363.1 - 0.011 15.2 0.0 0.02 14.3 0.0 1.4 1 0 0 1 1 1 0 AAA-like domain MobB PF03205.9 EGC40363.1 - 0.014 15.1 0.0 0.026 14.2 0.0 1.4 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B RecA PF00154.16 EGC40363.1 - 0.014 14.4 0.0 0.03 13.3 0.0 1.5 1 0 0 1 1 1 0 recA bacterial DNA recombination protein AAA_28 PF13521.1 EGC40363.1 - 0.023 14.6 0.1 0.039 13.9 0.1 1.3 1 0 0 1 1 1 0 AAA domain DUF3863 PF12979.2 EGC40363.1 - 0.023 13.3 0.0 0.037 12.6 0.0 1.2 1 0 0 1 1 1 0 Domain of Unknown Function with PDB structure (DUF3863) NACHT PF05729.7 EGC40363.1 - 0.029 14.0 0.0 0.065 12.8 0.0 1.6 1 0 0 1 1 1 0 NACHT domain AAA_19 PF13245.1 EGC40363.1 - 0.051 13.3 0.2 0.11 12.2 0.2 1.5 1 0 0 1 1 1 0 Part of AAA domain Picorna_P3A PF06363.6 EGC40364.1 - 0.028 14.3 0.0 0.046 13.7 0.0 1.4 1 0 0 1 1 1 0 Picornaviridae P3A protein Pkinase PF00069.20 EGC40365.1 - 2.5e-33 115.3 0.2 5.4e-33 114.2 0.2 1.5 1 0 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40365.1 - 1.4e-18 66.9 0.0 7.5e-18 64.5 0.0 2.0 1 1 0 1 1 1 1 Protein tyrosine kinase TPR_12 PF13424.1 EGC40365.1 - 7e-15 54.7 6.3 4.2e-05 23.3 1.7 4.7 3 1 2 5 5 5 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC40365.1 - 1.5e-09 37.0 7.7 0.034 14.0 0.1 7.1 8 0 0 8 8 8 3 Tetratricopeptide repeat TPR_1 PF00515.23 EGC40365.1 - 7.3e-08 31.7 8.0 0.033 13.8 0.2 5.6 6 0 0 6 6 6 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC40365.1 - 7.8e-07 28.6 4.7 0.033 13.8 0.1 4.7 2 1 2 5 5 5 3 TPR repeat TPR_16 PF13432.1 EGC40365.1 - 6.7e-05 23.4 0.9 1.1 10.0 0.0 4.0 4 2 1 5 5 4 2 Tetratricopeptide repeat TPR_10 PF13374.1 EGC40365.1 - 6.7e-05 22.6 0.9 0.048 13.5 0.1 3.9 5 0 0 5 5 5 1 Tetratricopeptide repeat APH PF01636.18 EGC40365.1 - 0.002 17.8 0.0 0.0033 17.1 0.0 1.2 1 0 0 1 1 1 1 Phosphotransferase enzyme family TPR_7 PF13176.1 EGC40365.1 - 0.0031 17.1 2.3 3.9 7.4 0.1 3.8 4 0 0 4 4 3 2 Tetratricopeptide repeat TPR_8 PF13181.1 EGC40365.1 - 0.0035 17.0 11.6 0.8 9.6 0.1 5.8 6 0 0 6 6 5 1 Tetratricopeptide repeat RIO1 PF01163.17 EGC40365.1 - 0.015 14.6 0.3 0.055 12.8 0.0 2.0 2 0 0 2 2 2 0 RIO1 family DUF3856 PF12968.2 EGC40365.1 - 0.023 14.5 0.4 0.37 10.5 0.0 2.4 2 0 0 2 2 2 0 Domain of Unknown Function (DUF3856) Kdo PF06293.9 EGC40365.1 - 0.024 13.7 0.2 0.046 12.7 0.1 1.4 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family TPR_6 PF13174.1 EGC40365.1 - 0.039 14.4 5.4 15 6.3 0.0 5.5 6 0 0 6 6 5 0 Tetratricopeptide repeat TPR_14 PF13428.1 EGC40365.1 - 0.085 13.5 0.0 2e+02 3.0 0.0 4.6 5 0 0 5 5 5 0 Tetratricopeptide repeat DUF1635 PF07795.6 EGC40365.1 - 0.11 11.8 1.4 0.24 10.7 1.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1635) DUF3285 PF11688.3 EGC40365.1 - 3 7.5 8.0 4.5 6.9 1.0 2.6 2 0 0 2 2 2 0 Protein of unknown function (DUF3285) DUF3430 PF11912.3 EGC40366.1 - 4.4e-31 108.3 24.6 4.4e-31 108.3 17.1 1.6 1 1 1 2 2 2 1 Protein of unknown function (DUF3430) TPR_12 PF13424.1 EGC40367.1 - 8.7e-13 48.0 4.5 3.9e-06 26.7 0.4 3.1 3 0 0 3 3 3 2 Tetratricopeptide repeat TPR_1 PF00515.23 EGC40367.1 - 5.9e-09 35.1 3.0 0.0049 16.4 0.0 4.3 4 0 0 4 4 4 3 Tetratricopeptide repeat TPR_11 PF13414.1 EGC40367.1 - 9.5e-07 28.3 3.7 0.00019 21.0 0.2 3.0 3 0 0 3 3 3 2 TPR repeat TPR_7 PF13176.1 EGC40367.1 - 2.5e-06 26.8 0.7 0.52 10.2 0.0 3.7 3 0 0 3 3 3 3 Tetratricopeptide repeat TPR_2 PF07719.12 EGC40367.1 - 3.3e-06 26.6 1.0 0.32 11.0 0.0 3.8 4 0 0 4 4 4 2 Tetratricopeptide repeat Imm24 PF15570.1 EGC40367.1 - 0.014 15.0 1.7 0.052 13.2 0.4 2.5 2 1 0 2 2 2 0 Immunity protein 24 TPR_8 PF13181.1 EGC40367.1 - 0.015 14.9 8.0 0.79 9.6 0.0 4.8 4 0 0 4 4 4 0 Tetratricopeptide repeat TPR_19 PF14559.1 EGC40367.1 - 0.02 15.2 0.6 9.7 6.6 0.0 2.8 3 0 0 3 3 3 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC40367.1 - 0.063 13.2 0.9 0.53 10.2 0.0 2.9 4 0 0 4 4 4 0 Tetratricopeptide repeat VP9 PF09625.5 EGC40367.1 - 0.086 12.6 2.1 2.7 7.8 0.2 3.0 3 0 0 3 3 3 0 VP9 protein Prefoldin PF02996.12 EGC40367.1 - 0.2 11.3 4.2 3.2 7.4 0.3 3.2 3 0 0 3 3 3 0 Prefoldin subunit FYVE_2 PF02318.11 EGC40368.1 - 2.6e-07 30.5 5.9 5e-07 29.6 4.1 1.4 1 0 0 1 1 1 1 FYVE-type zinc finger TIG PF01833.19 EGC40368.1 - 2.7e-07 30.4 10.4 2.2e-05 24.3 0.3 3.3 3 0 0 3 3 3 2 IPT/TIG domain FYVE PF01363.16 EGC40368.1 - 2.2e-06 27.4 5.2 4e-06 26.6 3.6 1.4 1 0 0 1 1 1 1 FYVE zinc finger zf-piccolo PF05715.8 EGC40368.1 - 0.1 12.6 6.8 0.28 11.2 4.7 1.8 1 0 0 1 1 1 0 Piccolo Zn-finger SHQ1 PF04925.10 EGC40369.1 - 1.9e-62 210.1 5.9 3.6e-62 209.1 4.1 1.4 1 0 0 1 1 1 1 SHQ1 protein Tir_receptor_C PF07489.6 EGC40370.1 - 0.00079 19.2 0.9 0.00079 19.2 0.6 1.8 2 0 0 2 2 2 1 Translocated intimin receptor (Tir) C-terminus FNIP PF05725.7 EGC40371.1 - 7.6e-19 67.3 7.0 1.3e-11 44.2 0.2 2.8 2 1 0 3 3 3 2 FNIP Repeat LRR_5 PF13306.1 EGC40371.1 - 0.034 13.8 0.0 0.055 13.1 0.0 1.3 1 1 0 1 1 1 0 Leucine rich repeats (6 copies) HEAT_2 PF13646.1 EGC40372.1 - 3.4e-14 52.9 0.0 0.00053 20.2 0.0 7.5 4 3 5 9 9 9 7 HEAT repeats HEAT PF02985.17 EGC40372.1 - 3.2e-12 45.4 11.4 0.0072 16.3 0.0 10.4 12 0 0 12 12 12 3 HEAT repeat HEAT_EZ PF13513.1 EGC40372.1 - 2.3e-10 40.6 0.1 0.016 15.6 0.0 8.3 8 2 2 10 10 10 1 HEAT-like repeat Cnd1 PF12717.2 EGC40372.1 - 6.9e-07 29.2 22.9 0.0045 16.8 0.8 6.1 4 2 1 6 6 6 4 non-SMC mitotic condensation complex subunit 1 Vac14_Fab1_bd PF12755.2 EGC40372.1 - 8e-06 26.1 12.1 0.00034 20.9 0.1 6.2 7 1 1 8 8 8 1 Vacuolar 14 Fab1-binding region IBN_N PF03810.14 EGC40372.1 - 0.0092 15.8 5.6 0.011 15.6 0.7 3.5 4 0 0 4 4 4 1 Importin-beta N-terminal domain DUF3385 PF11865.3 EGC40372.1 - 2.5 8.0 11.4 20 5.1 0.0 5.6 6 1 0 6 6 6 0 Domain of unknown function (DUF3385) DEAD PF00270.24 EGC40373.1 - 7.8e-37 126.3 0.1 1.2e-36 125.7 0.1 1.3 1 0 0 1 1 1 1 DEAD/DEAH box helicase Helicase_C PF00271.26 EGC40373.1 - 1.5e-25 88.8 0.2 2.8e-24 84.7 0.1 2.3 2 0 0 2 2 2 1 Helicase conserved C-terminal domain CMS1 PF14617.1 EGC40373.1 - 1.1e-05 24.6 0.0 2.1e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U3-containing 90S pre-ribosomal complex subunit ResIII PF04851.10 EGC40373.1 - 6.1e-05 22.9 0.0 0.00015 21.6 0.0 1.7 1 0 0 1 1 1 1 Type III restriction enzyme, res subunit ARPC4 PF05856.7 EGC40374.1 - 9.8e-75 249.6 5.6 1.1e-74 249.4 3.9 1.0 1 0 0 1 1 1 1 ARP2/3 complex 20 kDa subunit (ARPC4) Mak10 PF04112.8 EGC40375.1 - 4.9e-25 87.6 0.1 4.9e-25 87.6 0.1 2.9 3 1 1 4 4 4 1 Mak10 subunit, NatC N(alpha)-terminal acetyltransferase FNIP PF05725.7 EGC40376.1 - 1.6e-35 120.7 34.5 4.5e-10 39.3 2.7 5.5 3 2 3 6 6 6 5 FNIP Repeat ACPS PF01648.15 EGC40378.1 - 3.6e-30 104.1 0.1 4.1e-30 103.9 0.1 1.0 1 0 0 1 1 1 1 4'-phosphopantetheinyl transferase superfamily F-box PF00646.28 EGC40379.1 - 0.021 14.4 0.0 0.04 13.5 0.0 1.5 1 0 0 1 1 1 0 F-box domain Secretin_N_2 PF07655.8 EGC40379.1 - 3.2 8.1 22.4 2.1 8.8 14.2 1.7 2 0 0 2 2 2 0 Secretin N-terminal domain Ras PF00071.17 EGC40380.1 - 1.9e-46 157.4 0.2 2.9e-46 156.7 0.1 1.3 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC40380.1 - 3.6e-20 72.6 0.1 3.6e-20 72.6 0.1 1.9 2 1 0 2 2 2 1 Miro-like protein Arf PF00025.16 EGC40380.1 - 1.3e-09 37.4 0.1 2.5e-09 36.6 0.1 1.5 1 0 0 1 1 1 1 ADP-ribosylation factor family GTP_EFTU PF00009.22 EGC40380.1 - 2.9e-05 23.6 1.2 0.00025 20.5 0.5 2.3 1 1 0 1 1 1 1 Elongation factor Tu GTP binding domain SRPRB PF09439.5 EGC40380.1 - 3.7e-05 23.0 0.1 3.7e-05 23.0 0.1 2.1 2 1 1 3 3 3 1 Signal recognition particle receptor beta subunit AAA_28 PF13521.1 EGC40380.1 - 0.078 12.9 0.0 0.12 12.2 0.0 1.4 1 0 0 1 1 1 0 AAA domain Macoilin PF09726.4 EGC40380.1 - 1 7.5 15.1 1.2 7.3 10.5 1.1 1 0 0 1 1 1 0 Transmembrane protein Hist_deacetyl PF00850.14 EGC40381.1 - 2.1e-78 263.7 0.1 2.9e-78 263.2 0.0 1.1 1 0 0 1 1 1 1 Histone deacetylase domain FNIP PF05725.7 EGC40384.1 - 0.0006 19.7 43.5 0.028 14.3 0.4 10.0 7 4 1 8 8 8 4 FNIP Repeat DUF3586 PF12131.3 EGC40385.1 - 0.04 13.9 2.2 0.04 13.9 1.5 3.5 2 2 2 4 4 4 0 Protein of unknown function (DUF3586) DUF4419 PF14388.1 EGC40386.1 - 2.1e-95 319.3 4.4 2.4e-95 319.1 3.0 1.0 1 0 0 1 1 1 1 Domain of unknown function (DUF4419) FNIP PF05725.7 EGC40387.1 - 2.3e-128 417.9 175.1 2.9e-12 46.3 0.9 20.8 9 2 12 21 21 21 20 FNIP Repeat Pkinase PF00069.20 EGC40387.1 - 1.7e-38 132.2 0.2 1.9e-37 128.8 0.1 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40387.1 - 2.9e-26 92.1 0.0 4.4e-26 91.5 0.0 1.2 1 0 0 1 1 1 1 Protein tyrosine kinase Kinase-like PF14531.1 EGC40387.1 - 6.2e-06 25.3 0.0 1.4e-05 24.1 0.0 1.5 1 0 0 1 1 1 1 Kinase-like TFIIA_gamma_N PF02268.11 EGC40387.1 - 4e-05 23.1 0.6 3.2 7.4 0.0 6.2 7 1 1 8 8 8 1 Transcription initiation factor IIA, gamma subunit, helical domain APH PF01636.18 EGC40387.1 - 0.018 14.7 0.0 0.028 14.1 0.0 1.2 1 0 0 1 1 1 0 Phosphotransferase enzyme family GED PF02212.13 EGC40387.1 - 0.24 11.3 1.3 3.8 7.4 0.1 3.1 3 0 0 3 3 3 0 Dynamin GTPase effector domain YrbL-PhoP_reg PF10707.4 EGC40387.1 - 0.27 10.5 0.5 9.4 5.5 0.0 2.2 2 0 0 2 2 2 0 PhoP regulatory network protein YrbL Kdo PF06293.9 EGC40387.1 - 0.48 9.4 0.0 0.72 8.8 0.0 1.2 1 0 0 1 1 1 0 Lipopolysaccharide kinase (Kdo/WaaP) family zf-RING_2 PF13639.1 EGC40388.1 - 3.1e-09 36.4 9.3 5.4e-09 35.7 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC40388.1 - 1.4e-08 34.2 11.7 3.7e-08 32.8 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC40388.1 - 4.6e-07 29.8 4.9 1.2e-06 28.5 3.4 1.7 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC40388.1 - 4e-06 26.4 6.5 6.5e-06 25.7 4.5 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40388.1 - 1.3e-05 25.1 9.8 2.3e-05 24.3 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40388.1 - 2.8e-05 23.7 10.7 5.3e-05 22.8 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC40388.1 - 0.00035 20.3 8.8 0.00093 19.0 6.1 1.8 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC40388.1 - 0.0053 16.3 9.5 0.011 15.2 6.6 1.6 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-UDP PF14569.1 EGC40388.1 - 0.016 14.9 1.1 0.044 13.5 0.8 1.7 1 0 0 1 1 1 0 Zinc-binding RING-finger zf-Apc11 PF12861.2 EGC40388.1 - 0.016 14.9 2.9 0.035 13.9 2.0 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-MIZ PF02891.15 EGC40388.1 - 0.037 13.5 8.5 0.076 12.5 5.9 1.5 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGC40388.1 - 0.13 12.0 5.9 0.43 10.3 4.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger AAA_23 PF13476.1 EGC40388.1 - 0.31 11.3 41.6 0.03 14.6 13.4 2.3 2 0 0 2 2 2 0 AAA domain FYDLN_acid PF09538.5 EGC40388.1 - 0.31 11.6 0.1 0.31 11.6 0.1 4.0 4 1 0 4 4 2 0 Protein of unknown function (FYDLN_acid) CT47 PF15623.1 EGC40388.1 - 0.43 10.2 22.9 0.66 9.6 15.9 1.2 1 0 0 1 1 1 0 Cancer/testis gene family 47 IncA PF04156.9 EGC40388.1 - 0.49 9.9 11.6 0.78 9.2 8.1 1.4 1 0 0 1 1 1 0 IncA protein DUF1272 PF06906.6 EGC40388.1 - 0.76 9.6 5.8 1.5 8.7 4.0 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) PBP_sp32 PF07222.7 EGC40388.1 - 5.7 6.0 19.8 10 5.1 13.7 1.4 1 0 0 1 1 1 0 Proacrosin binding protein sp32 zf-RING_2 PF13639.1 EGC40389.1 - 3.6e-09 36.3 9.3 5.9e-09 35.6 6.4 1.4 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC40389.1 - 1.5e-08 34.1 11.7 4e-08 32.7 8.1 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC40389.1 - 1.7e-06 27.9 5.2 1.7e-06 27.9 3.6 1.9 2 0 0 2 2 2 1 RING-H2 zinc finger zf-C3HC4_3 PF13920.1 EGC40389.1 - 6.5e-06 25.7 6.9 1.1e-05 25.0 4.8 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40389.1 - 1.4e-05 24.9 9.8 2.5e-05 24.2 6.8 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40389.1 - 3.1e-05 23.6 10.7 5.8e-05 22.7 7.4 1.5 1 0 0 1 1 1 1 zinc-RING finger domain zf-C3HC4_4 PF15227.1 EGC40389.1 - 0.00043 20.0 8.8 0.001 18.9 6.1 1.7 1 0 0 1 1 1 1 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC40389.1 - 0.0051 16.3 9.5 0.012 15.1 6.6 1.7 1 0 0 1 1 1 1 RING/Ubox like zinc-binding domain zf-Apc11 PF12861.2 EGC40389.1 - 0.017 14.9 3.0 0.039 13.7 2.1 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-UDP PF14569.1 EGC40389.1 - 0.031 14.0 1.3 0.031 14.0 0.9 2.4 2 1 0 2 2 1 0 Zinc-binding RING-finger zf-MIZ PF02891.15 EGC40389.1 - 0.046 13.2 8.7 0.075 12.5 6.0 1.3 1 0 0 1 1 1 0 MIZ/SP-RING zinc finger zf-RING_UBOX PF13445.1 EGC40389.1 - 0.12 12.1 5.9 0.46 10.2 4.1 2.1 1 0 0 1 1 1 0 RING-type zinc-finger FYDLN_acid PF09538.5 EGC40389.1 - 0.29 11.7 0.1 0.29 11.7 0.0 4.5 4 1 0 4 4 3 0 Protein of unknown function (FYDLN_acid) DUF1272 PF06906.6 EGC40389.1 - 0.48 10.3 5.9 0.99 9.3 4.1 1.5 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) YwhD PF08741.5 EGC40390.1 - 0.082 12.3 0.1 0.088 12.2 0.1 1.1 1 0 0 1 1 1 0 YwhD family DUF2372 PF10178.4 EGC40390.1 - 0.1 12.7 0.1 0.13 12.4 0.1 1.2 1 0 0 1 1 1 0 Uncharacterised conserved protein (DUF2372) NAD_binding_10 PF13460.1 EGC40391.1 - 5.3e-12 46.1 0.0 7.5e-12 45.6 0.0 1.1 1 0 0 1 1 1 1 NADH(P)-binding NAD_binding_4 PF07993.7 EGC40391.1 - 4.7e-05 22.4 0.0 0.0014 17.5 0.0 2.1 1 1 0 2 2 2 1 Male sterility protein Semialdhyde_dh PF01118.19 EGC40391.1 - 0.026 14.8 0.0 0.05 13.9 0.0 1.6 1 1 0 1 1 1 0 Semialdehyde dehydrogenase, NAD binding domain NmrA PF05368.8 EGC40391.1 - 0.046 12.9 0.0 0.076 12.2 0.0 1.4 1 0 0 1 1 1 0 NmrA-like family Aminotran_5 PF00266.14 EGC40392.1 - 1.1e-40 139.5 0.0 1.3e-40 139.3 0.0 1.0 1 0 0 1 1 1 1 Aminotransferase class-V HEAT_EZ PF13513.1 EGC40393.1 - 6.4e-31 106.0 0.2 3.8e-12 46.3 0.0 11.0 10 2 2 12 12 12 3 HEAT-like repeat HEAT PF02985.17 EGC40393.1 - 1.2e-26 90.3 2.3 0.01 15.8 0.0 11.3 11 0 0 11 11 11 5 HEAT repeat HEAT_2 PF13646.1 EGC40393.1 - 7.1e-22 77.4 0.0 2.2e-05 24.6 0.0 6.8 3 2 6 9 9 9 7 HEAT repeats Vac14_Fab1_bd PF12755.2 EGC40393.1 - 7.8e-11 42.2 0.1 0.024 15.0 0.0 5.6 5 2 3 8 8 6 4 Vacuolar 14 Fab1-binding region Cnd1 PF12717.2 EGC40393.1 - 1.9e-10 40.9 1.8 0.00074 19.4 0.0 4.8 3 1 2 5 5 5 3 non-SMC mitotic condensation complex subunit 1 Arm PF00514.18 EGC40393.1 - 8.5e-10 38.1 3.7 1.2 9.0 0.0 7.4 8 0 0 8 8 8 3 Armadillo/beta-catenin-like repeat IBN_N PF03810.14 EGC40393.1 - 2.2e-09 37.1 0.1 1.8e-08 34.1 0.0 2.8 2 0 0 2 2 2 1 Importin-beta N-terminal domain MMS19_C PF12460.3 EGC40393.1 - 0.00027 19.7 11.7 0.0036 16.1 0.5 5.1 4 2 1 5 5 5 2 RNAPII transcription regulator C-terminal RIX1 PF08167.7 EGC40393.1 - 0.00072 19.2 1.8 0.18 11.4 0.0 4.1 3 2 1 4 4 4 1 rRNA processing/ribosome biogenesis Xpo1 PF08389.7 EGC40393.1 - 0.002 18.0 0.5 0.3 10.9 0.2 4.2 3 1 0 3 3 3 1 Exportin 1-like protein Cohesin_HEAT PF12765.2 EGC40393.1 - 0.0048 16.8 0.1 11 6.1 0.0 4.4 4 0 0 4 4 4 0 HEAT repeat associated with sister chromatid cohesion DUF4042 PF13251.1 EGC40393.1 - 0.01 15.3 0.5 0.16 11.4 0.2 3.1 3 1 0 3 3 3 0 Domain of unknown function (DUF4042) HEAT_PBS PF03130.11 EGC40393.1 - 0.073 13.5 0.0 4.1 8.1 0.0 3.4 2 0 0 2 2 2 0 PBS lyase HEAT-like repeat Nucleoplasmin PF03066.10 EGC40393.1 - 0.65 9.4 4.5 1.1 8.7 3.1 1.4 1 0 0 1 1 1 0 Nucleoplasmin PBP1_TM PF14812.1 EGC40393.1 - 1 9.7 7.5 2.3 8.5 5.2 1.5 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal PQ-loop PF04193.9 EGC40394.1 - 3.3e-21 74.5 6.3 7e-12 44.7 1.1 3.2 4 0 0 4 4 4 2 PQ loop repeat CTV_P6 PF06706.6 EGC40394.1 - 0.05 13.0 0.1 1.4 8.4 0.0 2.6 2 0 0 2 2 2 0 Citrus tristeza virus 6-kDa protein MtN3_slv PF03083.11 EGC40394.1 - 0.22 11.4 11.4 0.49 10.2 2.9 3.5 2 2 0 2 2 2 0 Sugar efflux transporter for intercellular exchange Oxysterol_BP PF01237.13 EGC40395.1 - 5.3e-40 136.9 5.5 8.6e-40 136.3 3.8 1.3 1 0 0 1 1 1 1 Oxysterol-binding protein Oxysterol_BP PF01237.13 EGC40396.1 - 5.3e-53 179.7 8.9 1.2e-52 178.5 6.2 1.5 1 1 0 1 1 1 1 Oxysterol-binding protein B3 PF02362.16 EGC40396.1 - 0.0035 16.9 3.1 0.012 15.1 0.0 2.4 2 0 0 2 2 2 1 B3 DNA binding domain RNase_H PF00075.19 EGC40396.1 - 0.046 14.0 1.3 0.38 11.0 0.8 2.1 2 0 0 2 2 2 0 RNase H Band_7 PF01145.20 EGC40397.1 - 8.6e-38 130.0 0.9 2.6e-37 128.4 0.6 1.7 1 1 0 1 1 1 1 SPFH domain / Band 7 family Band_7_1 PF13421.1 EGC40397.1 - 0.0074 15.8 0.3 0.012 15.1 0.2 1.4 1 0 0 1 1 1 1 SPFH domain-Band 7 family PDR_CDR PF06422.7 EGC40397.1 - 0.029 14.0 0.1 0.061 12.9 0.0 1.5 1 0 0 1 1 1 0 CDR ABC transporter Shisa PF13908.1 EGC40397.1 - 0.087 13.0 0.0 0.15 12.1 0.0 1.3 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator DUF4609 PF15382.1 EGC40397.1 - 0.23 11.1 2.0 0.79 9.4 0.2 2.5 3 0 0 3 3 3 0 Domain of unknown function (DUF4609) Prenyltrans PF00432.16 EGC40398.1 - 2e-21 75.1 1.6 3e-09 36.2 0.0 6.0 6 0 0 6 6 6 4 Prenyltransferase and squalene oxidase repeat Prenyltrans_2 PF13249.1 EGC40398.1 - 6.6e-11 42.6 0.0 2.6e-05 24.5 0.0 2.8 2 1 1 3 3 3 2 Prenyltransferase-like SnoaL PF07366.7 EGC40399.1 - 0.0022 17.5 0.0 0.0049 16.4 0.0 1.5 1 1 0 1 1 1 1 SnoaL-like polyketide cyclase Longin PF13774.1 EGC40400.1 - 4.9e-19 67.6 2.8 1.3e-18 66.3 1.9 1.7 1 0 0 1 1 1 1 Regulated-SNARE-like domain Synaptobrevin PF00957.16 EGC40400.1 - 2.7e-15 55.7 0.4 4.8e-15 54.9 0.3 1.4 1 0 0 1 1 1 1 Synaptobrevin DUF829 PF05705.9 EGC40400.1 - 0.012 15.3 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Eukaryotic protein of unknown function (DUF829) DUF948 PF06103.6 EGC40400.1 - 0.21 11.4 1.5 2.6 7.9 0.8 2.2 2 0 0 2 2 2 0 Bacterial protein of unknown function (DUF948) adh_short PF00106.20 EGC40401.1 - 2.7e-18 66.4 0.0 4e-18 65.8 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC40401.1 - 1.6e-09 37.9 0.0 2.2e-09 37.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC40401.1 - 0.00053 19.7 0.0 0.0013 18.3 0.0 1.6 1 1 0 1 1 1 1 KR domain SIR2 PF02146.12 EGC40402.1 - 3.9e-25 88.6 0.2 9.5e-25 87.3 0.0 1.7 3 0 0 3 3 3 1 Sir2 family SIR2_2 PF13289.1 EGC40402.1 - 0.001 18.9 2.2 1.1 9.1 0.0 3.5 3 1 0 3 3 3 2 SIR2-like domain TPP_enzyme_M PF00205.17 EGC40402.1 - 0.053 13.2 0.0 0.19 11.4 0.0 1.9 2 0 0 2 2 2 0 Thiamine pyrophosphate enzyme, central domain Sir1 PF11603.3 EGC40403.1 - 0.14 12.2 1.6 0.2 11.7 1.1 1.2 1 0 0 1 1 1 0 Regulatory protein Sir1 DUF2681 PF10883.3 EGC40403.1 - 0.16 12.1 2.5 0.24 11.6 1.7 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF2681) Trypan_PARP PF05887.6 EGC40404.1 - 1.8e-05 24.5 131.3 0.00012 21.9 43.0 5.6 2 1 4 6 6 6 4 Procyclic acidic repetitive protein (PARP) YqzL PF14006.1 EGC40404.1 - 0.058 13.6 0.8 2.5 8.3 0.0 3.3 2 0 0 2 2 2 0 YqzL-like protein DUF1084 PF06454.6 EGC40405.1 - 1.5e-07 30.7 27.1 3.2e-07 29.6 18.8 1.4 1 0 0 1 1 1 1 Protein of unknown function (DUF1084) SAM_1 PF00536.25 EGC40405.1 - 0.0025 17.9 0.1 2.7 8.2 0.0 2.6 2 0 0 2 2 2 2 SAM domain (Sterile alpha motif) RabGAP-TBC PF00566.13 EGC40406.1 - 2.2e-52 177.6 2.0 2.2e-52 177.6 1.4 1.7 2 0 0 2 2 2 1 Rab-GTPase-TBC domain Drf_GBD PF06371.8 EGC40406.1 - 0.042 13.2 0.8 0.099 11.9 0.2 2.0 2 0 0 2 2 2 0 Diaphanous GTPase-binding Domain DUF3439 PF11921.3 EGC40406.1 - 0.76 9.5 11.9 1.8 8.3 8.2 1.6 1 0 0 1 1 1 0 Domain of unknown function (DUF3439) Herpes_capsid PF06112.6 EGC40406.1 - 0.84 9.6 8.6 2.2 8.3 5.9 1.8 1 0 0 1 1 1 0 Gammaherpesvirus capsid protein Mucin PF01456.12 EGC40406.1 - 1.5 8.5 22.6 2.5 7.8 15.7 1.2 1 0 0 1 1 1 0 Mucin-like glycoprotein RNase_P_p30 PF01876.11 EGC40407.1 - 4e-36 123.4 0.2 6.1e-36 122.9 0.1 1.3 1 0 0 1 1 1 1 RNase P subunit p30 CorC_HlyC PF03471.12 EGC40407.1 - 0.08 12.7 0.0 0.2 11.4 0.0 1.6 1 0 0 1 1 1 0 Transporter associated domain Choline_transpo PF04515.7 EGC40408.1 - 5.6e-38 130.5 27.4 6.4e-38 130.3 19.0 1.0 1 0 0 1 1 1 1 Plasma-membrane choline transporter Renin_r PF07850.9 EGC40408.1 - 4.7 7.6 7.2 1.9 8.8 2.9 2.1 1 1 0 2 2 2 0 Renin receptor-like protein DUF3498 PF12004.3 EGC40410.1 - 0.0037 16.4 10.5 0.0066 15.6 7.3 1.4 1 0 0 1 1 1 1 Domain of unknown function (DUF3498) KLRAQ PF10205.4 EGC40410.1 - 0.008 16.1 2.1 0.008 16.1 1.5 4.1 1 1 2 4 4 4 1 Predicted coiled-coil domain-containing protein PAZ_siRNAbind PF12212.3 EGC40410.1 - 0.01 15.4 0.2 0.01 15.4 0.1 3.1 3 0 0 3 3 3 0 Piwi/Argonaute/Zwille siRNA-binding domain Phage_holin_4 PF05105.7 EGC40411.1 - 0.2 11.3 4.1 0.42 10.2 2.8 1.5 1 0 0 1 1 1 0 Holin family Claudin_3 PF06653.6 EGC40411.1 - 0.22 11.2 4.8 0.32 10.6 3.4 1.3 1 0 0 1 1 1 0 Tight junction protein, Claudin-like DUF4145 PF13643.1 EGC40411.1 - 0.22 11.3 0.2 0.22 11.3 0.1 1.8 2 0 0 2 2 2 0 Domain of unknown function (DUF4145) Glyco_hydro_18 PF00704.23 EGC40412.1 - 0.0099 15.3 1.4 0.02 14.3 1.0 1.7 1 1 0 1 1 1 1 Glycosyl hydrolases family 18 XRCC4 PF06632.7 EGC40413.1 - 3.1e-18 65.7 22.8 1.4e-17 63.6 15.8 1.8 1 1 0 1 1 1 1 DNA double-strand break repair and V(D)J recombination protein XRCC4 DUF4610 PF15384.1 EGC40413.1 - 0.00061 19.3 2.3 1.1 8.8 1.3 2.5 2 0 0 2 2 2 2 Domain of unknown function (DUF4610) bZIP_1 PF00170.16 EGC40413.1 - 4.7 7.2 14.7 8.7 6.3 4.9 2.7 2 0 0 2 2 2 0 bZIP transcription factor TPP_enzyme_N PF02776.13 EGC40414.1 - 1.3e-43 148.4 0.1 4.5e-43 146.7 0.0 1.9 3 0 0 3 3 3 1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain TPP_enzyme_C PF02775.16 EGC40414.1 - 1.4e-24 86.4 0.0 1.7e-23 82.8 0.0 2.3 2 0 0 2 2 2 1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain TPP_enzyme_M PF00205.17 EGC40414.1 - 9.8e-17 60.9 0.0 2.1e-16 59.9 0.0 1.6 1 0 0 1 1 1 1 Thiamine pyrophosphate enzyme, central domain Ras PF00071.17 EGC40415.1 - 1.6e-43 147.8 0.1 2e-43 147.6 0.1 1.1 1 0 0 1 1 1 1 Ras family Miro PF08477.8 EGC40415.1 - 3.3e-16 59.8 0.0 4.7e-16 59.3 0.0 1.2 1 0 0 1 1 1 1 Miro-like protein Arf PF00025.16 EGC40415.1 - 3.4e-06 26.4 0.0 4.4e-06 26.0 0.0 1.1 1 0 0 1 1 1 1 ADP-ribosylation factor family MMR_HSR1 PF01926.18 EGC40415.1 - 5.8e-06 26.2 0.0 9.4e-06 25.5 0.0 1.4 1 1 0 1 1 1 1 50S ribosome-binding GTPase Septin PF00735.13 EGC40415.1 - 5.1e-05 22.4 0.0 7.8e-05 21.8 0.0 1.2 1 0 0 1 1 1 1 Septin RNA_helicase PF00910.17 EGC40415.1 - 0.00029 20.9 0.1 0.0011 19.1 0.0 1.9 3 0 0 3 3 2 1 RNA helicase AAA_24 PF13479.1 EGC40415.1 - 0.00051 19.6 0.0 0.00091 18.8 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC40415.1 - 0.00062 20.0 0.0 0.0011 19.3 0.0 1.4 1 0 0 1 1 1 1 AAA domain AAA_22 PF13401.1 EGC40415.1 - 0.0016 18.5 0.0 0.019 15.0 0.0 2.2 1 1 1 2 2 2 1 AAA domain NACHT PF05729.7 EGC40415.1 - 0.0073 15.9 0.0 0.011 15.4 0.0 1.2 1 0 0 1 1 1 1 NACHT domain MobB PF03205.9 EGC40415.1 - 0.011 15.4 0.0 0.023 14.4 0.0 1.5 1 0 0 1 1 1 0 Molybdopterin guanine dinucleotide synthesis protein B GTP_EFTU PF00009.22 EGC40415.1 - 0.011 15.1 0.0 2 7.7 0.0 2.1 1 1 0 2 2 2 0 Elongation factor Tu GTP binding domain AAA_16 PF13191.1 EGC40415.1 - 0.019 14.9 0.0 0.032 14.2 0.0 1.3 1 0 0 1 1 1 0 AAA ATPase domain Viral_helicase1 PF01443.13 EGC40415.1 - 0.02 14.4 0.0 0.031 13.8 0.0 1.3 1 0 0 1 1 1 0 Viral (Superfamily 1) RNA helicase DUF815 PF05673.8 EGC40415.1 - 0.028 13.3 0.0 0.05 12.5 0.0 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF815) DUF258 PF03193.11 EGC40415.1 - 0.028 13.5 0.0 0.054 12.6 0.0 1.5 1 0 0 1 1 1 0 Protein of unknown function, DUF258 AAA_14 PF13173.1 EGC40415.1 - 0.03 14.2 0.1 0.056 13.3 0.0 1.4 1 0 0 1 1 1 0 AAA domain MCM PF00493.18 EGC40415.1 - 0.034 12.9 0.0 0.056 12.2 0.0 1.3 1 0 0 1 1 1 0 MCM2/3/5 family ABC_tran PF00005.22 EGC40415.1 - 0.034 14.4 0.0 0.052 13.8 0.0 1.4 1 0 0 1 1 1 0 ABC transporter AAA PF00004.24 EGC40415.1 - 0.034 14.3 0.0 0.066 13.4 0.0 1.6 1 0 0 1 1 1 0 ATPase family associated with various cellular activities (AAA) AAA_10 PF12846.2 EGC40415.1 - 0.035 13.5 0.0 0.047 13.1 0.0 1.2 1 0 0 1 1 1 0 AAA-like domain AAA_17 PF13207.1 EGC40415.1 - 0.043 14.6 0.0 0.059 14.1 0.0 1.6 1 1 0 1 1 1 0 AAA domain Arch_ATPase PF01637.13 EGC40415.1 - 0.048 13.3 0.2 0.079 12.6 0.0 1.5 2 0 0 2 2 2 0 Archaeal ATPase PduV-EutP PF10662.4 EGC40415.1 - 0.12 11.9 0.0 0.33 10.4 0.0 1.7 2 0 0 2 2 2 0 Ethanolamine utilisation - propanediol utilisation AAA_29 PF13555.1 EGC40415.1 - 0.13 11.7 0.0 0.37 10.3 0.0 1.8 1 0 0 1 1 1 0 P-loop containing region of AAA domain ELMO_CED12 PF04727.8 EGC40416.1 - 1.4e-47 161.4 2.3 2.2e-47 160.7 0.0 2.4 2 1 0 2 2 2 1 ELMO/CED-12 family Erf4 PF10256.4 EGC40417.1 - 0.012 15.4 8.6 0.03 14.1 3.4 2.8 2 1 0 2 2 2 0 Golgin subfamily A member 7/ERF4 family CitMHS PF03600.11 EGC40417.1 - 0.23 9.9 4.0 0.3 9.6 2.8 1.1 1 0 0 1 1 1 0 Citrate transporter HTH_23 PF13384.1 EGC40418.1 - 0.00017 21.1 0.0 0.00038 20.0 0.0 1.6 1 0 0 1 1 1 1 Homeodomain-like domain HTH_28 PF13518.1 EGC40418.1 - 0.00073 19.4 0.1 0.0014 18.5 0.1 1.5 1 0 0 1 1 1 1 Helix-turn-helix domain HTH_29 PF13551.1 EGC40418.1 - 0.0053 16.8 0.0 0.0084 16.2 0.0 1.3 1 0 0 1 1 1 1 Winged helix-turn helix PAX PF00292.13 EGC40418.1 - 0.026 14.2 0.0 0.057 13.1 0.0 1.6 1 0 0 1 1 1 0 'Paired box' domain HTH_38 PF13936.1 EGC40418.1 - 0.07 12.6 0.1 0.15 11.6 0.1 1.6 1 0 0 1 1 1 0 Helix-turn-helix domain TrmB PF01978.14 EGC40418.1 - 0.13 11.9 0.9 0.53 10.0 0.0 2.0 2 0 0 2 2 2 0 Sugar-specific transcriptional regulator TrmB HTH_Tnp_Tc3_2 PF01498.13 EGC40418.1 - 0.37 10.8 3.1 0.2 11.7 0.4 1.7 2 0 0 2 2 2 0 Transposase EF-hand_1 PF00036.27 EGC40419.1 - 0.0059 15.8 0.3 0.04 13.2 0.1 2.2 2 0 0 2 2 2 1 EF hand EF-hand_6 PF13405.1 EGC40419.1 - 0.039 13.8 0.0 0.85 9.6 0.0 2.3 2 0 0 2 2 2 0 EF-hand domain EF-hand_7 PF13499.1 EGC40419.1 - 0.13 12.3 0.1 0.86 9.7 0.0 2.1 1 1 1 2 2 2 0 EF-hand domain pair DUF3650 PF12368.3 EGC40419.1 - 0.78 9.2 0.1 0.78 9.2 0.1 2.4 4 0 0 4 4 4 0 Protein of unknown function (DUF3650) Coiled PF05710.7 EGC40420.1 - 0.14 12.6 9.1 0.17 12.3 6.3 1.1 1 0 0 1 1 1 0 Coiled coil Coiled PF05710.7 EGC40421.1 - 0.048 14.1 11.7 0.058 13.8 8.1 1.1 1 0 0 1 1 1 0 Coiled coil Ribosomal_L18_c PF14204.1 EGC40424.1 - 0.14 12.7 2.6 0.16 12.5 1.2 1.5 2 0 0 2 2 2 0 Ribosomal L18 C-terminal region Meleagrin PF08189.6 EGC40424.1 - 0.71 9.3 3.5 0.91 9.0 0.8 2.1 2 0 0 2 2 2 0 Meleagrin/Cygnin family Pox_L3_FP4 PF03339.9 EGC40424.1 - 1 7.7 3.6 1.2 7.4 2.5 1.0 1 0 0 1 1 1 0 Poxvirus L3/FP4 protein Selenoprotein_S PF06936.6 EGC40426.1 - 1.3 8.4 5.7 1.9 7.9 3.9 1.2 1 0 0 1 1 1 0 Selenoprotein S (SelS) PT PF04886.7 EGC40427.1 - 0.0019 17.4 26.3 0.004 16.4 18.3 1.5 1 0 0 1 1 1 1 PT repeat Glycoprotein PF03409.10 EGC40427.1 - 0.54 8.9 9.9 0.63 8.7 6.8 1.2 1 0 0 1 1 1 0 Transmembrane glycoprotein Pkinase PF00069.20 EGC40428.1 - 3.6e-38 131.1 0.0 3.6e-38 131.1 0.0 3.6 3 1 0 3 3 3 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40428.1 - 5.7e-29 100.9 0.0 5.7e-29 100.9 0.0 2.2 2 1 0 2 2 2 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EGC40428.1 - 6.9e-09 35.6 3.6 6.9e-09 35.6 2.5 4.3 2 2 1 3 3 3 1 Ribonuclease 2-5A APH PF01636.18 EGC40428.1 - 0.19 11.4 0.0 0.19 11.4 0.0 1.8 2 0 0 2 2 2 0 Phosphotransferase enzyme family FNIP PF05725.7 EGC40429.1 - 1.2e-26 92.3 86.8 3.7e-09 36.3 1.0 12.8 9 3 3 12 12 12 10 FNIP Repeat DUF1510 PF07423.6 EGC40430.1 - 0.00011 21.6 25.5 0.00011 21.6 17.7 2.0 1 1 1 2 2 2 1 Protein of unknown function (DUF1510) Neur_chan_memb PF02932.11 EGC40430.1 - 1.4 8.7 31.8 2.3 8.0 22.0 1.4 1 0 0 1 1 1 0 Neurotransmitter-gated ion-channel transmembrane region Brevenin PF03032.10 EGC40430.1 - 2 8.3 0.0 2 8.3 0.0 5.0 1 1 1 2 2 2 0 Brevenin/esculentin/gaegurin/rugosin family PAP2 PF01569.16 EGC40431.1 - 5.5e-09 35.7 0.6 5.5e-09 35.7 0.4 2.3 2 0 0 2 2 2 1 PAP2 superfamily FNIP PF05725.7 EGC40432.1 - 4.3e-40 135.4 96.4 3.8e-12 45.9 0.5 12.5 10 2 3 13 13 13 9 FNIP Repeat Pkinase PF00069.20 EGC40433.1 - 1.2e-33 116.3 0.0 1.2e-33 116.3 0.0 2.3 2 0 0 2 2 2 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40433.1 - 2.5e-22 79.1 0.0 7.7e-22 77.5 0.0 1.8 1 0 0 1 1 1 1 Protein tyrosine kinase Ribonuc_2-5A PF06479.7 EGC40433.1 - 4.5e-06 26.5 0.8 4.5e-06 26.5 0.6 3.3 2 1 1 3 3 3 2 Ribonuclease 2-5A Pyridox_oxidase PF01243.15 EGC40435.1 - 1.3e-22 79.5 0.0 2.1e-22 78.9 0.0 1.3 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase PNPOx_C PF10590.4 EGC40435.1 - 6.3e-15 54.3 1.6 1.5e-14 53.2 1.1 1.7 1 0 0 1 1 1 1 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region Pyridox_oxase_2 PF12766.2 EGC40435.1 - 0.00024 21.3 0.1 0.00044 20.5 0.0 1.4 1 0 0 1 1 1 1 Pyridoxamine 5'-phosphate oxidase FNIP PF05725.7 EGC40436.1 - 1.9e-13 50.0 14.8 1.7e-06 27.8 1.9 3.7 4 0 0 4 4 4 3 FNIP Repeat LRR_5 PF13306.1 EGC40436.1 - 8.7e-06 25.4 2.4 0.0065 16.1 0.2 1.7 1 1 1 2 2 2 2 Leucine rich repeats (6 copies) SapB_1 PF05184.10 EGC40437.1 - 2.6e-05 23.9 10.0 0.021 14.6 0.1 3.8 4 1 0 4 4 4 2 Saposin-like type B, region 1 zinc_ribbon_4 PF13717.1 EGC40437.1 - 0.00018 21.1 1.3 0.4 10.3 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGC40437.1 - 0.00027 20.4 1.7 0.48 10.0 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain SapB_2 PF03489.12 EGC40437.1 - 0.0042 17.0 0.1 0.0042 17.0 0.0 2.2 3 0 0 3 3 3 1 Saposin-like type B, region 2 Copper-fist PF00649.13 EGC40437.1 - 0.036 13.2 3.8 0.11 11.7 0.2 2.7 3 0 0 3 3 3 0 Copper fist DNA binding domain Rubredoxin PF00301.15 EGC40437.1 - 0.037 13.8 0.3 4.2 7.3 0.0 2.7 2 0 0 2 2 2 0 Rubredoxin Lipoprotein_11 PF03260.8 EGC40437.1 - 0.046 12.7 0.0 0.061 12.3 0.0 1.1 1 0 0 1 1 1 0 Lepidopteran low molecular weight (30 kD) lipoprotein Imm5 PF14423.1 EGC40437.1 - 0.29 10.7 2.5 0.64 9.6 0.2 2.0 1 1 1 2 2 2 0 Immunity protein Imm5 SapB_2 PF03489.12 EGC40438.1 - 4.5e-13 48.9 8.4 1.4e-07 31.4 0.3 2.9 3 0 0 3 3 3 2 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC40438.1 - 7.5e-07 28.8 11.9 0.00031 20.4 0.2 4.4 4 1 0 4 4 4 2 Saposin-like type B, region 1 zinc_ribbon_4 PF13717.1 EGC40438.1 - 0.00072 19.1 1.9 1.2 8.8 0.0 2.7 2 0 0 2 2 2 2 zinc-ribbon domain zinc_ribbon_5 PF13719.1 EGC40438.1 - 0.00079 18.9 1.7 0.9 9.1 0.4 2.6 2 0 0 2 2 2 2 zinc-ribbon domain Rubredoxin PF00301.15 EGC40438.1 - 0.005 16.6 0.2 3.6 7.5 0.0 2.9 2 0 0 2 2 2 2 Rubredoxin H2TH PF06831.9 EGC40438.1 - 0.17 11.6 0.2 0.52 10.0 0.0 1.9 2 1 0 2 2 2 0 Formamidopyrimidine-DNA glycosylase H2TH domain zf-RanBP PF00641.13 EGC40438.1 - 0.36 9.9 4.0 11 5.1 0.2 2.8 2 0 0 2 2 2 0 Zn-finger in Ran binding protein and others DnaJ PF00226.26 EGC40439.1 - 1.5e-19 69.4 0.2 1.5e-19 69.4 0.1 2.7 3 0 0 3 3 3 1 DnaJ domain Ripply PF14998.1 EGC40439.1 - 1.5 9.0 8.6 1.9 8.6 4.5 2.4 2 1 0 2 2 2 0 Transcription Regulator DUF3840 PF12944.2 EGC40439.1 - 2.8 7.8 5.7 0.86 9.4 0.9 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3840) Mucin PF01456.12 EGC40439.1 - 3.3 7.4 24.5 6.6 6.5 16.9 1.4 1 0 0 1 1 1 0 Mucin-like glycoprotein Band_3_cyto PF07565.8 EGC40439.1 - 5.2 6.4 14.7 9.5 5.6 0.3 2.2 2 0 0 2 2 2 0 Band 3 cytoplasmic domain zf-CCHC PF00098.18 EGC40440.1 - 0.00017 21.3 1.5 0.00038 20.2 1.0 1.6 1 0 0 1 1 1 1 Zinc knuckle Endotoxin_N PF03945.9 EGC40441.1 - 1.8e-08 34.0 0.3 1e-06 28.3 0.0 2.9 2 1 0 2 2 2 1 delta endotoxin, N-terminal domain DUF1240 PF06836.7 EGC40442.1 - 0.054 13.7 0.2 0.15 12.3 0.1 1.7 1 1 1 2 2 2 0 Protein of unknown function (DUF1240) zf-C3HC4_3 PF13920.1 EGC40443.1 - 1.9e-05 24.2 7.5 3.1e-05 23.5 5.2 1.3 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40443.1 - 0.00018 21.4 11.5 0.00026 20.9 6.6 2.0 2 0 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) LIM PF00412.17 EGC40443.1 - 0.0051 16.8 7.3 0.051 13.6 2.4 2.3 2 0 0 2 2 2 1 LIM domain zf-C3HC4 PF00097.20 EGC40443.1 - 0.01 15.4 11.2 0.01 15.4 7.7 1.6 2 0 0 2 2 2 0 Zinc finger, C3HC4 type (RING finger) Prok-RING_4 PF14447.1 EGC40443.1 - 0.018 14.5 2.8 0.03 13.8 2.0 1.4 1 0 0 1 1 1 0 Prokaryotic RING finger family 4 zf-RING_5 PF14634.1 EGC40443.1 - 0.035 13.8 11.6 0.19 11.4 8.3 2.0 1 1 1 2 2 2 0 zinc-RING finger domain zf-RING_4 PF14570.1 EGC40443.1 - 0.038 13.5 9.5 0.068 12.7 6.2 1.8 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain zf-RING_2 PF13639.1 EGC40443.1 - 0.11 12.2 8.5 0.087 12.6 5.0 1.5 2 0 0 2 2 2 0 Ring finger domain zf-CHY PF05495.7 EGC40443.1 - 0.97 9.6 9.8 3.1 8.0 6.8 1.9 1 1 0 1 1 1 0 CHY zinc finger DUF3624 PF12292.3 EGC40443.1 - 1.6 9.1 6.2 11 6.5 0.3 2.2 2 0 0 2 2 2 0 Protein of unknown function (DUF3624) DZR PF12773.2 EGC40443.1 - 2.1 8.2 9.1 0.44 10.3 1.7 2.2 1 1 1 2 2 2 0 Double zinc ribbon Vps54 PF07928.7 EGC40444.1 - 5e-46 156.1 1.7 5e-46 156.1 1.2 2.4 3 0 0 3 3 3 1 Vps54-like protein RDM PF11002.3 EGC40444.1 - 0.032 13.8 3.4 0.049 13.3 0.4 2.7 3 0 0 3 3 3 0 RFPL defining motif (RDM) EGF_2 PF07974.8 EGC40445.1 - 0.05 13.7 11.6 0.13 12.4 8.1 1.7 1 0 0 1 1 1 0 EGF-like domain PP2C PF00481.16 EGC40446.1 - 3.3e-53 180.6 0.0 6e-53 179.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PP2C_2 PF13672.1 EGC40446.1 - 0.0004 19.8 0.0 0.00082 18.8 0.0 1.4 1 0 0 1 1 1 1 Protein phosphatase 2C PEMT PF04191.8 EGC40447.1 - 2e-52 175.7 19.3 1.8e-32 111.5 2.3 3.1 3 0 0 3 3 3 2 Phospholipid methyltransferase zf-TRAF PF02176.13 EGC40448.1 - 1.7e-12 47.5 16.1 4.8e-12 46.0 4.6 4.3 1 1 4 5 5 5 2 TRAF-type zinc finger zf-RING_2 PF13639.1 EGC40448.1 - 2.9e-08 33.4 8.7 2.9e-08 33.4 6.0 3.3 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC40448.1 - 1.2e-07 31.6 10.4 1.2e-07 31.6 7.2 3.4 3 0 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC40448.1 - 1.6e-06 27.6 10.1 1.6e-06 27.6 7.0 3.7 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) U-box PF04564.10 EGC40448.1 - 7e-05 22.7 0.1 0.00026 20.8 0.0 2.0 2 0 0 2 2 2 1 U-box domain zf-rbx1 PF12678.2 EGC40448.1 - 0.0016 18.4 8.4 0.0016 18.4 5.8 4.8 3 2 0 3 3 3 1 RING-H2 zinc finger zf-RING_5 PF14634.1 EGC40448.1 - 0.0025 17.4 10.3 0.0025 17.4 7.1 3.3 3 1 0 3 3 3 1 zinc-RING finger domain zf-C3HC4_3 PF13920.1 EGC40448.1 - 0.0058 16.2 10.7 0.0058 16.2 7.4 2.9 2 1 0 2 2 2 1 Zinc finger, C3HC4 type (RING finger) zf-RING_6 PF14835.1 EGC40448.1 - 0.011 15.5 6.7 0.011 15.5 4.6 2.0 2 0 0 2 2 2 0 zf-RING of BARD1-type protein zf-BED PF02892.10 EGC40448.1 - 5.1 6.9 12.4 0.12 12.1 1.3 3.5 3 1 1 4 4 4 0 BED zinc finger DUF4254 PF14063.1 EGC40449.1 - 0.13 11.8 0.1 0.13 11.8 0.1 2.0 2 0 0 2 2 2 0 Protein of unknown function (DUF4254) ING PF12998.2 EGC40449.1 - 2.3 8.5 13.4 68 3.8 9.1 2.3 1 1 0 1 1 1 0 Inhibitor of growth proteins N-terminal histone-binding EGF_2 PF07974.8 EGC40450.1 - 0.00024 21.2 12.9 0.00024 21.2 8.9 2.6 2 0 0 2 2 2 1 EGF-like domain UPF0731 PF14982.1 EGC40450.1 - 0.25 11.2 0.0 0.74 9.7 0.0 1.7 1 0 0 1 1 1 0 UPF0731 family ADH_zinc_N PF00107.21 EGC40452.1 - 1.9e-28 98.5 0.0 3.3e-28 97.8 0.0 1.3 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC40452.1 - 1.4e-20 74.4 0.0 4.9e-20 72.7 0.0 1.8 2 0 0 2 2 2 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC40452.1 - 2.1e-08 33.8 0.0 3.8e-08 33.0 0.0 1.4 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain EAL PF00563.15 EGC40452.1 - 0.01 15.3 0.1 0.43 10.0 0.0 2.3 1 1 1 2 2 2 0 EAL domain DapB_N PF01113.15 EGC40452.1 - 0.013 15.3 0.1 0.056 13.3 0.0 2.0 2 1 0 2 2 2 0 Dihydrodipicolinate reductase, N-terminus adh_short_C2 PF13561.1 EGC40452.1 - 0.12 12.1 0.0 0.19 11.4 0.0 1.3 1 0 0 1 1 1 0 Enoyl-(Acyl carrier protein) reductase adh_short_C2 PF13561.1 EGC40453.1 - 8.9e-23 81.2 0.0 1.4e-22 80.6 0.0 1.3 1 1 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase adh_short PF00106.20 EGC40453.1 - 9.1e-20 71.2 0.0 1.3e-19 70.6 0.0 1.3 1 0 0 1 1 1 1 short chain dehydrogenase Daxx PF03344.10 EGC40453.1 - 0.0028 16.2 21.7 0.0035 15.8 15.0 1.1 1 0 0 1 1 1 1 Daxx Family DUF1776 PF08643.5 EGC40453.1 - 0.018 14.2 0.1 0.018 14.2 0.1 1.6 2 0 0 2 2 2 0 Fungal family of unknown function (DUF1776) KR PF08659.5 EGC40453.1 - 0.057 13.0 0.0 0.094 12.3 0.0 1.4 1 0 0 1 1 1 0 KR domain Z1 PF10593.4 EGC40453.1 - 0.18 11.0 1.8 0.25 10.5 1.2 1.3 1 0 0 1 1 1 0 Z1 domain Caldesmon PF02029.10 EGC40453.1 - 0.21 9.9 19.5 0.26 9.6 13.5 1.2 1 0 0 1 1 1 0 Caldesmon BSP_II PF05432.6 EGC40453.1 - 0.26 10.5 20.1 0.4 9.9 13.9 1.4 1 0 0 1 1 1 0 Bone sialoprotein II (BSP-II) CDC45 PF02724.9 EGC40453.1 - 0.39 8.7 9.6 0.4 8.6 6.6 1.1 1 0 0 1 1 1 0 CDC45-like protein DUF2457 PF10446.4 EGC40453.1 - 0.44 9.2 12.4 0.68 8.5 8.6 1.3 1 0 0 1 1 1 0 Protein of unknown function (DUF2457) DUF702 PF05142.7 EGC40453.1 - 0.65 10.1 3.0 0.94 9.6 1.4 1.6 2 0 0 2 2 2 0 Domain of unknown function (DUF702) PBP1_TM PF14812.1 EGC40453.1 - 1.1 9.6 10.1 2.5 8.4 7.0 1.6 1 0 0 1 1 1 0 Transmembrane domain of transglycosylase PBP1 at N-terminal DUF3824 PF12868.2 EGC40453.1 - 1.1 10.1 8.2 1.9 9.4 5.7 1.3 1 0 0 1 1 1 0 Domain of unknwon function (DUF3824) Radial_spoke PF04712.7 EGC40453.1 - 1.5 7.5 20.6 2.2 6.9 14.3 1.3 1 0 0 1 1 1 0 Radial spokehead-like protein Pox_RNA_Pol_19 PF05320.7 EGC40453.1 - 1.6 8.4 13.5 3.7 7.2 9.4 1.6 1 0 0 1 1 1 0 Poxvirus DNA-directed RNA polymerase 19 kDa subunit DUF2890 PF11081.3 EGC40453.1 - 1.9 8.5 22.4 3.3 7.7 15.5 1.4 1 0 0 1 1 1 0 Protein of unknown function (DUF2890) Lin-8 PF03353.10 EGC40453.1 - 2.6 7.2 17.6 4.4 6.4 12.2 1.4 1 0 0 1 1 1 0 Ras-mediated vulval-induction antagonist Ycf1 PF05758.7 EGC40453.1 - 3.7 5.1 12.9 4.1 4.9 8.9 1.2 1 0 0 1 1 1 0 Ycf1 Vfa1 PF08432.5 EGC40453.1 - 3.9 7.4 16.8 9.5 6.2 11.6 1.7 1 0 0 1 1 1 0 AAA-ATPase Vps4-associated protein 1 TRAP_alpha PF03896.11 EGC40453.1 - 4.1 6.3 11.3 6 5.7 7.8 1.3 1 0 0 1 1 1 0 Translocon-associated protein (TRAP), alpha subunit CENP-B_dimeris PF09026.5 EGC40453.1 - 6.8 7.0 19.5 14 5.9 13.5 1.5 1 0 0 1 1 1 0 Centromere protein B dimerisation domain FNIP PF05725.7 EGC40454.1 - 2.1e-43 145.9 36.9 6.4e-15 54.8 0.2 8.3 6 2 2 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 EGC40454.1 - 0.0046 16.6 3.5 0.085 12.5 0.2 2.7 1 1 2 3 3 3 3 Leucine rich repeats (6 copies) Amidinotransf PF02274.12 EGC40455.1 - 5.8e-69 232.2 1.4 7.3e-46 156.5 0.1 3.1 3 0 0 3 3 3 3 Amidinotransferase CBS PF00571.23 EGC40456.1 - 2.2e-26 91.3 2.8 2.7e-09 36.6 0.1 4.4 4 0 0 4 4 4 4 CBS domain Methyltransf_11 PF08241.7 EGC40457.1 - 2.5e-18 66.3 0.0 4.4e-18 65.5 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC40457.1 - 3.2e-18 65.7 0.2 5.4e-18 65.0 0.1 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC40457.1 - 3.4e-16 59.3 0.0 5e-16 58.8 0.0 1.3 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC40457.1 - 9.7e-15 54.8 0.0 1.8e-14 54.0 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40457.1 - 2.9e-11 43.9 0.0 4.8e-11 43.2 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC40457.1 - 2.3e-09 37.4 0.0 3.8e-09 36.8 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_9 PF08003.6 EGC40457.1 - 1.3e-07 30.6 0.0 2.3e-07 29.8 0.0 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) Ubie_methyltran PF01209.13 EGC40457.1 - 1.3e-06 27.6 0.0 1.6e-06 27.3 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGC40457.1 - 5.8e-05 23.0 0.0 9.2e-05 22.4 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Pox_MCEL PF03291.11 EGC40457.1 - 7.1e-05 21.8 0.1 0.00025 20.0 0.1 1.8 1 1 0 1 1 1 1 mRNA capping enzyme CMAS PF02353.15 EGC40457.1 - 0.00016 20.8 0.0 0.00023 20.3 0.0 1.2 1 0 0 1 1 1 1 Mycolic acid cyclopropane synthetase NodS PF05401.6 EGC40457.1 - 0.00095 18.6 0.0 0.0019 17.6 0.0 1.4 1 0 0 1 1 1 1 Nodulation protein S (NodS) MTS PF05175.9 EGC40457.1 - 0.0011 18.3 0.0 0.0024 17.2 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase small domain PrmA PF06325.8 EGC40457.1 - 0.0019 17.3 0.0 0.0028 16.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal protein L11 methyltransferase (PrmA) Methyltransf_4 PF02390.12 EGC40457.1 - 0.039 12.9 0.0 0.73 8.8 0.0 2.3 3 0 0 3 3 3 0 Putative methyltransferase WWE PF02825.15 EGC40457.1 - 0.048 13.0 0.1 0.093 12.1 0.1 1.4 1 0 0 1 1 1 0 WWE domain Dict-STAT-coil PF09267.5 EGC40458.1 - 0.054 13.7 0.4 0.058 13.6 0.3 1.1 1 0 0 1 1 1 0 Dictyostelium STAT, coiled coil DUF3887 PF13026.1 EGC40458.1 - 0.066 13.4 0.2 0.073 13.3 0.1 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3887) Endotoxin_N PF03945.9 EGC40459.1 - 3.7e-07 29.7 0.7 8.4e-07 28.5 0.5 1.5 1 1 0 1 1 1 1 delta endotoxin, N-terminal domain KR PF08659.5 EGC40460.1 - 1.3e-05 24.9 0.0 2e-05 24.3 0.0 1.2 1 0 0 1 1 1 1 KR domain adh_short PF00106.20 EGC40460.1 - 0.00013 21.8 0.0 0.00021 21.2 0.0 1.2 1 0 0 1 1 1 1 short chain dehydrogenase Methyltransf_31 PF13847.1 EGC40460.1 - 0.019 14.5 10.7 0.022 14.3 1.7 2.4 1 1 0 2 2 2 0 Methyltransferase domain Methyltransf_23 PF13489.1 EGC40460.1 - 0.052 13.2 0.1 0.12 12.1 0.0 1.6 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_11 PF08241.7 EGC40460.1 - 0.08 13.4 0.0 0.82 10.1 0.0 2.2 2 0 0 2 2 2 0 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40460.1 - 0.14 12.7 0.0 0.86 10.2 0.0 2.0 2 0 0 2 2 2 0 Methyltransferase domain Dicty_CTDC PF00526.13 EGC40461.1 - 3.1e-22 77.9 51.3 1.4e-09 37.5 2.4 9.6 9 1 0 9 9 9 5 Dictyostelium (slime mold) repeat DNA_pol_A_exo1 PF01612.15 EGC40462.1 - 4.4e-19 68.6 0.0 1.3e-18 67.1 0.0 1.7 1 0 0 1 1 1 1 3'-5' exonuclease Toxin_58 PF15536.1 EGC40462.1 - 0.06 13.2 0.0 0.12 12.1 0.0 1.5 1 0 0 1 1 1 0 Putative toxin 58 eIF-1a PF01176.14 EGC40463.1 - 3e-26 90.6 0.0 4.5e-26 90.0 0.0 1.3 1 0 0 1 1 1 1 Translation initiation factor 1A / IF-1 Peptidase_M24 PF00557.19 EGC40464.1 - 1.8e-47 161.6 0.0 2.1e-47 161.3 0.0 1.1 1 0 0 1 1 1 1 Metallopeptidase family M24 zf-MYND PF01753.13 EGC40464.1 - 0.001 18.8 3.2 0.002 17.9 2.2 1.5 1 0 0 1 1 1 1 MYND finger zf-HIT PF04438.11 EGC40464.1 - 0.077 12.6 5.9 0.24 11.0 4.1 1.9 1 0 0 1 1 1 0 HIT zinc finger HTH_17 PF12728.2 EGC40465.1 - 0.55 10.5 2.6 0.85 9.9 0.1 2.4 3 0 0 3 3 3 0 Helix-turn-helix domain Pyr_excise PF03013.9 EGC40466.1 - 0.022 14.5 0.6 0.022 14.5 0.4 2.5 2 0 0 2 2 2 0 Pyrimidine dimer DNA glycosylase Cation_efflux PF01545.16 EGC40467.1 - 1.6e-08 33.9 5.9 6.6e-08 31.9 4.1 2.0 1 1 0 1 1 1 1 Cation efflux family EFG_II PF14492.1 EGC40467.1 - 0.16 11.8 0.1 0.26 11.1 0.1 1.3 1 0 0 1 1 1 0 Elongation Factor G, domain II DUF2626 PF11117.3 EGC40467.1 - 3.9 7.9 13.1 2.5 8.5 0.6 2.7 1 1 1 2 2 2 0 Protein of unknown function (DUF2626) EGF_2 PF07974.8 EGC40468.1 - 0.00014 21.9 12.9 0.00014 21.9 8.9 2.6 2 0 0 2 2 2 1 EGF-like domain DUF1905 PF08922.6 EGC40468.1 - 0.0018 17.8 0.0 0.73 9.4 0.0 2.6 2 0 0 2 2 2 2 Domain of unknown function (DUF1905) EGF_alliinase PF04863.8 EGC40468.1 - 0.66 9.9 6.1 1.7 8.6 4.2 1.6 1 0 0 1 1 1 0 Alliinase EGF-like domain SapB_2 PF03489.12 EGC40475.1 - 4.5e-13 48.9 15.1 7.8e-09 35.3 0.8 3.4 4 0 0 4 4 4 2 Saposin-like type B, region 2 SapB_1 PF05184.10 EGC40475.1 - 3.5e-12 45.8 14.1 2.5e-08 33.5 0.4 3.9 4 1 0 4 4 4 2 Saposin-like type B, region 1 Rubredoxin PF00301.15 EGC40475.1 - 0.03 14.1 3.5 5.1 7.0 0.0 3.1 3 0 0 3 3 3 0 Rubredoxin Aminotran_1_2 PF00155.16 EGC40476.1 - 1.8e-51 175.2 0.0 2.2e-51 174.9 0.0 1.1 1 0 0 1 1 1 1 Aminotransferase class I and II Beta_elim_lyase PF01212.16 EGC40476.1 - 0.0036 16.4 0.0 0.006 15.7 0.0 1.3 1 0 0 1 1 1 1 Beta-eliminating lyase FNIP PF05725.7 EGC40477.1 - 5.7e-83 272.6 81.1 4.1e-13 49.0 0.5 12.6 9 2 3 13 13 13 12 FNIP Repeat Pkinase PF00069.20 EGC40477.1 - 3.5e-50 170.5 4.7 2.5e-49 167.7 3.3 2.0 1 1 0 1 1 1 1 Protein kinase domain Pkinase_Tyr PF07714.12 EGC40477.1 - 8.5e-30 103.6 1.0 2.6e-29 102.1 0.5 1.9 1 1 0 1 1 1 1 Protein tyrosine kinase APH PF01636.18 EGC40477.1 - 0.073 12.7 0.0 0.48 10.1 0.0 1.9 1 1 1 2 2 2 0 Phosphotransferase enzyme family zf-C3HC4_2 PF13923.1 EGC40478.1 - 4.5e-09 36.1 9.3 4.5e-09 36.1 6.5 3.4 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC40478.1 - 6.1e-09 35.5 8.1 6.1e-09 35.5 5.6 3.6 3 2 1 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EGC40478.1 - 1.1e-06 28.2 8.1 1.1e-06 28.2 5.6 3.3 3 1 0 3 3 3 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC40478.1 - 1.5e-06 27.9 10.0 1.5e-06 27.9 6.9 2.8 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EGC40478.1 - 1.7e-05 24.6 0.0 3.4e-05 23.7 0.0 1.5 1 0 0 1 1 1 1 U-box domain zf-C3HC4_3 PF13920.1 EGC40478.1 - 0.00013 21.5 4.3 0.00013 21.5 3.0 3.2 2 1 0 2 2 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_5 PF14634.1 EGC40478.1 - 0.00017 21.2 5.9 0.00017 21.2 4.1 3.2 3 0 0 3 3 3 1 zinc-RING finger domain zf-RING_6 PF14835.1 EGC40478.1 - 0.00043 20.0 3.4 0.00043 20.0 2.4 2.4 2 0 0 2 2 2 1 zf-RING of BARD1-type protein zf-Nse PF11789.3 EGC40478.1 - 0.0061 16.0 3.5 0.0061 16.0 2.4 2.9 3 1 1 4 4 4 1 Zinc-finger of the MIZ type in Nse subunit Sina PF03145.11 EGC40478.1 - 0.0092 15.6 11.6 0.24 11.0 0.2 2.4 1 1 0 2 2 2 2 Seven in absentia protein family zf-TRAF PF02176.13 EGC40478.1 - 0.031 14.6 7.2 0.031 14.6 5.0 4.3 2 2 2 4 4 4 0 TRAF-type zinc finger DUF1830 PF08865.6 EGC40478.1 - 0.042 13.4 0.2 0.14 11.7 0.0 2.0 2 0 0 2 2 2 0 Domain of unknown function (DUF1830) DZR PF12773.2 EGC40478.1 - 0.27 11.0 11.5 0.23 11.3 3.5 3.3 2 1 1 3 3 3 0 Double zinc ribbon zf-RING_4 PF14570.1 EGC40478.1 - 0.5 10.0 19.0 0.042 13.4 5.3 3.0 2 1 0 2 2 2 0 RING/Ubox like zinc-binding domain Auto_anti-p27 PF06677.7 EGC40478.1 - 1.5 8.6 8.5 0.66 9.7 1.0 3.2 3 0 0 3 3 3 0 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) zf-TRAF PF02176.13 EGC40479.1 - 1e-13 51.3 36.3 2.7e-07 30.8 4.8 4.8 4 1 1 5 5 5 3 TRAF-type zinc finger zf-C3HC4_2 PF13923.1 EGC40479.1 - 2.3e-07 30.7 12.9 2.3e-07 30.7 8.9 3.5 3 1 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC40479.1 - 2.8e-07 30.2 10.6 2.8e-07 30.2 7.4 3.4 4 0 0 4 4 4 1 Ring finger domain zf-C3HC4 PF00097.20 EGC40479.1 - 7.6e-05 22.2 14.0 7.6e-05 22.2 9.7 4.0 5 0 0 5 5 5 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC40479.1 - 0.00081 19.2 9.4 0.00081 19.2 6.5 3.7 3 2 1 4 4 3 1 zinc finger of C3HC4-type, RING U-box PF04564.10 EGC40479.1 - 0.0031 17.4 0.1 0.015 15.2 0.1 2.1 1 1 0 1 1 1 1 U-box domain Sina PF03145.11 EGC40479.1 - 0.0047 16.6 0.3 0.0047 16.6 0.2 3.7 1 1 2 3 3 3 1 Seven in absentia protein family zf-RING_UBOX PF13445.1 EGC40479.1 - 0.014 15.1 8.8 0.049 13.3 6.1 2.0 1 0 0 1 1 1 0 RING-type zinc-finger MRP-63 PF14978.1 EGC40479.1 - 0.053 13.9 0.2 0.2 12.1 0.0 2.0 2 0 0 2 2 2 0 Mitochondrial ribosome protein 63 DUF1244 PF06844.6 EGC40479.1 - 0.091 12.5 0.6 0.22 11.3 0.4 1.6 1 0 0 1 1 1 0 Protein of unknown function (DUF1244) zf-Nse PF11789.3 EGC40479.1 - 0.72 9.4 10.0 0.85 9.1 5.1 2.5 2 0 0 2 2 2 0 Zinc-finger of the MIZ type in Nse subunit zf-RING_6 PF14835.1 EGC40479.1 - 4.4 7.1 12.9 0.099 12.4 2.9 2.7 2 2 0 2 2 2 0 zf-RING of BARD1-type protein FNIP PF05725.7 EGC40480.1 - 2.2e-54 181.1 61.0 1.4e-13 50.5 1.4 10.2 3 2 9 13 13 13 13 FNIP Repeat DUF1769 PF08588.5 EGC40480.1 - 0.071 13.0 10.8 0.24 11.3 0.0 5.1 4 2 2 6 6 6 0 Protein of unknown function (DUF1769) Ribosomal_S4e PF00900.15 EGC40481.1 - 1.3e-28 98.5 0.2 3.1e-28 97.2 0.1 1.7 1 0 0 1 1 1 1 Ribosomal family S4e RS4NT PF08071.7 EGC40481.1 - 2.8e-20 71.8 7.2 6.9e-20 70.6 5.0 1.7 1 0 0 1 1 1 1 RS4NT (NUC023) domain S4 PF01479.20 EGC40481.1 - 9.1e-09 34.6 0.0 1.8e-08 33.6 0.0 1.5 1 0 0 1 1 1 1 S4 domain KOW PF00467.24 EGC40481.1 - 0.012 15.2 3.4 0.018 14.7 0.0 3.0 4 0 0 4 4 4 0 KOW motif PspA_IM30 PF04012.7 EGC40482.1 - 0.036 13.4 10.7 0.051 12.9 7.3 1.4 1 1 0 1 1 1 0 PspA/IM30 family DUF4559 PF15112.1 EGC40482.1 - 6.7 5.7 14.0 0.75 8.9 2.2 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF4559) RRM_5 PF13893.1 EGC40483.1 - 3.2e-46 154.9 1.7 1e-15 57.2 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_1 PF00076.17 EGC40483.1 - 1.6e-36 123.7 0.0 4.4e-09 35.8 0.0 4.4 4 0 0 4 4 4 4 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) RRM_6 PF14259.1 EGC40483.1 - 1.9e-32 111.0 0.0 9.3e-10 38.3 0.0 4.3 4 0 0 4 4 4 4 RNA recognition motif (a.k.a. RRM, RBD, or RNP domain) Limkain-b1 PF11608.3 EGC40483.1 - 0.00019 21.1 0.0 0.33 10.7 0.0 3.3 3 0 0 3 3 3 1 Limkain b1 RNA_bind PF08675.6 EGC40483.1 - 0.00019 21.3 0.0 0.24 11.4 0.0 3.0 3 0 0 3 3 3 2 RNA binding domain RNaseH_C PF09293.5 EGC40484.1 - 0.029 14.2 2.2 1.2 8.9 0.2 2.6 1 1 1 2 2 2 0 T4 RNase H, C terminal LacI PF00356.16 EGC40485.1 - 0.42 10.2 0.0 0.42 10.2 0.0 3.4 3 1 0 3 3 3 0 Bacterial regulatory proteins, lacI family Nucleoside_tran PF01733.13 EGC40485.1 - 0.48 9.5 4.1 0.47 9.5 2.4 1.4 1 1 0 1 1 1 0 Nucleoside transporter Secretin_N_2 PF07655.8 EGC40485.1 - 1.1 9.6 13.1 2.1 8.7 9.1 1.6 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.7 EGC40486.1 - 2.7e-67 222.4 32.1 8.5e-12 44.8 0.0 8.2 4 1 7 11 11 11 10 FNIP Repeat FBD PF08387.5 EGC40486.1 - 0.0032 16.8 0.4 0.13 11.7 0.0 3.0 3 0 0 3 3 3 1 FBD TatC PF00902.13 EGC40487.1 - 0.00064 19.1 0.0 0.00074 18.9 0.0 1.1 1 0 0 1 1 1 1 Sec-independent protein translocase protein (TatC) Claudin_2 PF13903.1 EGC40487.1 - 0.026 14.2 1.0 0.034 13.8 0.7 1.2 1 0 0 1 1 1 0 PMP-22/EMP/MP20/Claudin tight junction Methyltransf_12 PF08242.7 EGC40487.1 - 0.097 13.1 1.7 0.12 12.8 1.2 1.2 1 0 0 1 1 1 0 Methyltransferase domain Secretin_N_2 PF07655.8 EGC40487.1 - 0.19 12.1 18.5 0.28 11.5 12.8 1.3 1 0 0 1 1 1 0 Secretin N-terminal domain DUF912 PF06024.7 EGC40487.1 - 1 9.4 17.0 1.3 9.1 4.9 2.2 2 0 0 2 2 2 0 Nucleopolyhedrovirus protein of unknown function (DUF912) CH PF00307.26 EGC40489.1 - 1.2e-32 112.1 5.5 8.4e-18 64.3 0.1 2.9 3 1 0 3 3 3 2 Calponin homology (CH) domain CAMSAP_CH PF11971.3 EGC40489.1 - 0.013 15.1 1.9 1.3 8.7 0.0 3.9 3 2 0 3 3 3 0 CAMSAP CH domain Rod_cone_degen PF15201.1 EGC40489.1 - 0.14 11.9 0.6 0.34 10.7 0.4 1.6 1 0 0 1 1 1 0 Progressive rod-cone degeneration DUF1796 PF08795.5 EGC40489.1 - 2.9 7.5 9.1 3.5 7.2 4.9 2.2 2 1 0 2 2 2 0 Putative papain-like cysteine peptidase (DUF1796) LRR_6 PF13516.1 EGC40490.1 - 1.2e-21 74.3 90.6 0.0029 17.5 0.0 14.9 15 1 0 15 15 15 12 Leucine Rich repeat F-box-like PF12937.2 EGC40490.1 - 0.00075 19.1 0.7 0.0024 17.5 0.0 2.1 2 0 0 2 2 2 1 F-box-like LRR_4 PF12799.2 EGC40490.1 - 0.019 14.6 0.2 0.019 14.6 0.1 11.7 5 4 8 13 13 13 0 Leucine Rich repeats (2 copies) LRR_8 PF13855.1 EGC40490.1 - 0.023 14.4 61.8 0.079 12.7 0.1 10.2 6 4 1 8 8 8 0 Leucine rich repeat CBM_20 PF00686.14 EGC40491.1 - 2.5e-13 49.4 10.5 4.3e-08 32.6 0.1 4.1 4 0 0 4 4 4 3 Starch binding domain Podoplanin PF05808.6 EGC40491.1 - 0.00026 20.5 0.3 0.00049 19.6 0.2 1.4 1 0 0 1 1 1 1 Podoplanin zf-CCHC PF00098.18 EGC40492.1 - 1.8e-06 27.5 3.6 3.4e-06 26.6 2.5 1.5 1 0 0 1 1 1 1 Zinc knuckle Transcrip_act PF04949.8 EGC40492.1 - 0.13 11.8 5.9 0.37 10.4 0.6 2.1 2 0 0 2 2 2 0 Transcriptional activator DnaJ PF00226.26 EGC40493.1 - 7.6e-21 73.6 0.6 1.3e-20 72.8 0.4 1.4 1 0 0 1 1 1 1 DnaJ domain zf-MYND PF01753.13 EGC40493.1 - 2e-10 40.3 12.7 2.9e-10 39.8 8.8 1.2 1 0 0 1 1 1 1 MYND finger Chromo PF00385.19 EGC40495.1 - 2.6e-12 46.2 0.8 7e-12 44.8 0.5 1.8 1 0 0 1 1 1 1 Chromo (CHRromatin Organisation MOdifier) domain Paramecium_SA PF01508.11 EGC40496.1 - 0.0045 17.1 21.8 0.023 14.8 8.8 2.8 1 1 1 2 2 2 1 Paramecium surface antigen domain PSI PF01437.20 EGC40496.1 - 0.18 11.9 21.9 0.81 9.8 0.8 3.0 1 1 1 2 2 2 0 Plexin repeat Tetraspannin PF00335.15 EGC40496.1 - 0.4 9.9 5.7 0.48 9.6 3.9 1.2 1 0 0 1 1 1 0 Tetraspanin family TraN PF06986.6 EGC40496.1 - 2.7 7.2 18.0 4.9 6.4 12.5 1.5 1 1 0 1 1 1 0 Type-1V conjugative transfer system mating pair stabilisation Rad60-SLD PF11976.3 EGC40497.1 - 3.9e-21 74.5 0.2 4.7e-21 74.2 0.1 1.1 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like ubiquitin PF00240.18 EGC40497.1 - 2e-07 30.3 0.2 2.5e-07 29.9 0.1 1.2 1 0 0 1 1 1 1 Ubiquitin family IBR PF01485.16 EGC40498.1 - 1.4e-10 40.8 36.9 3.2e-10 39.7 8.2 4.3 3 1 0 3 3 3 2 IBR domain zf-RING_2 PF13639.1 EGC40498.1 - 1.2e-05 25.0 10.6 1.2e-05 25.0 7.4 3.1 3 0 0 3 3 3 1 Ring finger domain zf-C3HC4_2 PF13923.1 EGC40498.1 - 8.3e-05 22.5 7.6 8.3e-05 22.5 5.2 4.3 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC40498.1 - 9.8e-05 21.9 6.5 9.8e-05 21.9 4.5 4.7 3 2 1 4 4 4 1 Zinc finger, C3HC4 type (RING finger) PP-binding PF00550.20 EGC40501.1 - 3.6e-05 23.9 0.3 5.4e-05 23.3 0.2 1.3 1 0 0 1 1 1 1 Phosphopantetheine attachment site DUF3284 PF11687.3 EGC40501.1 - 0.03 14.0 0.9 0.046 13.4 0.6 1.4 1 0 0 1 1 1 0 Domain of unknown function (DUF3284) DUF2951 PF11166.3 EGC40501.1 - 0.22 11.3 2.0 0.27 11.1 0.6 1.7 1 1 0 1 1 1 0 Protein of unknown function (DUF2951) FNIP PF05725.7 EGC40502.1 - 7.2e-17 61.0 35.3 6.8e-06 25.9 1.7 7.0 5 2 2 7 7 7 6 FNIP Repeat LRR_5 PF13306.1 EGC40502.1 - 0.0006 19.5 16.6 0.0049 16.5 2.7 3.3 1 1 3 4 4 4 2 Leucine rich repeats (6 copies) DUF3651 PF12371.3 EGC40502.1 - 0.067 13.2 2.7 0.72 9.8 0.5 2.8 2 1 1 3 3 3 0 Protein of unknown function (DUF3651) LRR_8 PF13855.1 EGC40502.1 - 0.22 11.2 0.1 0.22 11.2 0.1 4.5 3 2 1 4 4 4 0 Leucine rich repeat Pyridoxal_deC PF00282.14 EGC40506.1 - 4.3e-74 249.1 0.0 5.5e-74 248.8 0.0 1.1 1 0 0 1 1 1 1 Pyridoxal-dependent decarboxylase conserved domain Malic_M PF03949.10 EGC40509.1 - 4.5e-95 318.0 0.0 6.2e-95 317.5 0.0 1.2 1 0 0 1 1 1 1 Malic enzyme, NAD binding domain malic PF00390.14 EGC40509.1 - 6.2e-70 234.4 0.0 3e-69 232.2 0.0 2.0 2 0 0 2 2 2 1 Malic enzyme, N-terminal domain TIG PF01833.19 EGC40510.1 - 5.5e-21 74.3 80.8 6.4e-07 29.2 2.0 8.6 7 1 1 8 8 8 7 IPT/TIG domain EGF_2 PF07974.8 EGC40510.1 - 0.022 14.9 12.1 0.051 13.7 8.4 1.7 1 0 0 1 1 1 0 EGF-like domain Laminin_EGF PF00053.19 EGC40510.1 - 0.095 12.6 8.1 0.22 11.4 5.6 1.6 1 0 0 1 1 1 0 Laminin EGF-like (Domains III and V) EGF PF00008.22 EGC40510.1 - 0.74 9.8 8.9 1.9 8.5 6.2 1.8 1 0 0 1 1 1 0 EGF-like domain Ndc80_HEC PF03801.8 EGC40511.1 - 0.13 11.6 0.1 0.14 11.6 0.1 1.0 1 0 0 1 1 1 0 HEC/Ndc80p family Methyltransf_11 PF08241.7 EGC40512.1 - 2.4e-18 66.4 0.0 4e-18 65.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC40512.1 - 6.1e-14 51.8 0.0 9.2e-14 51.2 0.0 1.4 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC40512.1 - 1.8e-11 44.3 0.0 3.1e-11 43.6 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_23 PF13489.1 EGC40512.1 - 3.6e-11 43.0 0.0 6e-11 42.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain Methyltransf_25 PF13649.1 EGC40512.1 - 1.7e-09 37.9 0.0 4.4e-09 36.6 0.0 1.7 2 0 0 2 2 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40512.1 - 4.2e-09 36.9 0.0 9.7e-09 35.7 0.0 1.5 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC40512.1 - 1.1e-08 34.5 0.0 1.5e-08 34.0 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_26 PF13659.1 EGC40512.1 - 2.5e-06 27.5 0.0 5.6e-06 26.3 0.0 1.5 1 1 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC40512.1 - 5.6e-06 25.8 0.2 1.7e-05 24.2 0.0 1.9 2 1 0 2 2 2 1 Methyltransferase small domain RrnaAD PF00398.15 EGC40512.1 - 9e-05 21.6 0.0 0.00016 20.7 0.0 1.4 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase Methyltransf_8 PF05148.10 EGC40512.1 - 0.0002 21.0 0.0 0.05 13.2 0.0 2.4 1 1 0 1 1 1 1 Hypothetical methyltransferase Methyltransf_PK PF05891.7 EGC40512.1 - 0.00025 20.4 0.0 0.00042 19.6 0.0 1.3 1 0 0 1 1 1 1 AdoMet dependent proline di-methyltransferase FtsJ PF01728.14 EGC40512.1 - 0.00033 20.7 0.2 0.0012 18.9 0.0 1.9 2 1 0 2 2 2 1 FtsJ-like methyltransferase Methyltransf_9 PF08003.6 EGC40512.1 - 0.0012 17.5 0.0 0.002 16.9 0.0 1.2 1 0 0 1 1 1 1 Protein of unknown function (DUF1698) tRNA_U5-meth_tr PF05958.6 EGC40512.1 - 0.0016 17.1 0.0 0.003 16.3 0.0 1.4 1 0 0 1 1 1 1 tRNA (Uracil-5-)-methyltransferase DREV PF05219.7 EGC40512.1 - 0.002 17.0 0.0 0.01 14.7 0.0 2.1 2 1 0 2 2 2 1 DREV methyltransferase Methyltransf_32 PF13679.1 EGC40512.1 - 0.0045 16.6 0.0 0.0071 16.0 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain PCMT PF01135.14 EGC40512.1 - 0.0057 16.2 0.0 0.015 14.8 0.0 1.6 2 0 0 2 2 2 1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) TehB PF03848.9 EGC40512.1 - 0.022 13.9 0.0 0.054 12.6 0.0 1.7 2 0 0 2 2 2 0 Tellurite resistance protein TehB NodS PF05401.6 EGC40512.1 - 0.037 13.4 0.0 0.057 12.8 0.0 1.2 1 0 0 1 1 1 0 Nodulation protein S (NodS) Methyltransf_4 PF02390.12 EGC40512.1 - 0.059 12.4 0.0 0.99 8.4 0.0 2.2 2 0 0 2 2 2 0 Putative methyltransferase Methyltransf_15 PF09445.5 EGC40512.1 - 0.086 12.3 0.0 0.15 11.5 0.0 1.4 1 0 0 1 1 1 0 RNA cap guanine-N2 methyltransferase DEAD PF00270.24 EGC40512.1 - 0.11 11.9 0.0 0.2 11.1 0.0 1.4 1 0 0 1 1 1 0 DEAD/DEAH box helicase Dickkopf_N PF04706.7 EGC40513.1 - 0.00056 20.0 12.6 0.00056 20.0 8.7 5.9 5 3 1 6 6 6 1 Dickkopf N-terminal cysteine-rich region TPR_11 PF13414.1 EGC40514.1 - 9.9e-53 175.6 8.7 4.7e-12 45.3 0.1 7.2 5 2 2 7 7 7 6 TPR repeat TPR_1 PF00515.23 EGC40514.1 - 1.8e-46 153.9 7.0 8e-09 34.7 0.1 9.7 9 0 0 9 9 9 8 Tetratricopeptide repeat TPR_2 PF07719.12 EGC40514.1 - 3.2e-37 123.4 2.1 3.4e-07 29.6 0.1 10.2 10 0 0 10 10 10 7 Tetratricopeptide repeat TPR_8 PF13181.1 EGC40514.1 - 1.4e-23 80.8 7.5 9.4e-06 25.0 0.0 8.4 9 0 0 9 9 8 4 Tetratricopeptide repeat TPR_17 PF13431.1 EGC40514.1 - 1.1e-21 75.1 14.2 0.00089 19.2 0.1 10.4 10 0 0 10 10 10 6 Tetratricopeptide repeat TPR_12 PF13424.1 EGC40514.1 - 8.9e-20 70.4 2.2 2.8e-05 23.9 0.0 6.1 3 1 3 6 6 6 4 Tetratricopeptide repeat TPR_16 PF13432.1 EGC40514.1 - 6.9e-18 64.8 0.0 6.3e-05 23.5 0.0 5.1 4 1 2 6 6 5 4 Tetratricopeptide repeat TPR_9 PF13371.1 EGC40514.1 - 2.1e-16 59.5 0.0 0.0055 16.5 0.0 5.9 4 1 2 6 6 6 4 Tetratricopeptide repeat Apc3 PF12895.2 EGC40514.1 - 2.9e-13 49.7 7.4 0.07 13.2 0.2 6.0 3 1 3 6 6 6 4 Anaphase-promoting complex, cyclosome, subunit 3 TPR_14 PF13428.1 EGC40514.1 - 1.4e-11 43.9 0.0 0.32 11.7 0.0 7.5 7 2 1 8 8 6 1 Tetratricopeptide repeat TPR_6 PF13174.1 EGC40514.1 - 1.6e-10 40.6 1.1 0.04 14.3 0.0 7.2 8 0 0 8 8 8 1 Tetratricopeptide repeat TPR_7 PF13176.1 EGC40514.1 - 2.4e-08 33.1 0.0 1.6 8.7 0.0 5.5 6 0 0 6 6 5 2 Tetratricopeptide repeat Fis1_TPR_C PF14853.1 EGC40514.1 - 2.1e-06 27.5 5.7 0.056 13.3 0.1 4.3 3 1 1 4 4 4 2 Fis1 C-terminal tetratricopeptide repeat TPR_19 PF14559.1 EGC40514.1 - 5e-05 23.5 0.0 10 6.5 0.0 5.4 4 2 2 6 6 6 0 Tetratricopeptide repeat TPR_10 PF13374.1 EGC40514.1 - 0.0021 17.9 0.2 13 5.8 0.0 4.4 4 0 0 4 4 4 0 Tetratricopeptide repeat DUF1697 PF08002.6 EGC40514.1 - 0.0073 16.3 0.2 0.023 14.7 0.2 1.9 1 0 0 1 1 1 1 Protein of unknown function (DUF1697) Aida_N PF08910.5 EGC40514.1 - 0.041 14.1 0.5 2.4 8.4 0.0 3.5 3 0 0 3 3 3 0 Aida N-terminus MIT PF04212.13 EGC40514.1 - 0.077 12.8 2.8 3 7.7 0.1 4.2 3 1 1 4 4 4 0 MIT (microtubule interacting and transport) domain ADH_zinc_N PF00107.21 EGC40515.1 - 2.2e-08 33.7 0.1 4.5e-08 32.6 0.0 1.6 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_zinc_N_2 PF13602.1 EGC40515.1 - 0.00024 21.9 0.0 0.0006 20.6 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase Saccharop_dh PF03435.13 EGC40515.1 - 0.0019 17.2 0.2 0.0025 16.8 0.1 1.2 1 0 0 1 1 1 1 Saccharopine dehydrogenase Hydrolase_3 PF08282.7 EGC40515.1 - 0.017 14.7 0.1 0.027 14.0 0.0 1.3 1 0 0 1 1 1 0 haloacid dehalogenase-like hydrolase NAD_binding_10 PF13460.1 EGC40515.1 - 0.068 13.1 0.4 0.11 12.5 0.3 1.3 1 0 0 1 1 1 0 NADH(P)-binding GTP_EFTU_D2 PF03144.20 EGC40515.1 - 0.097 12.8 1.5 0.71 10.0 0.1 3.0 3 0 0 3 3 3 0 Elongation factor Tu domain 2 DapB_N PF01113.15 EGC40515.1 - 0.11 12.3 0.9 0.41 10.5 0.5 2.0 1 1 1 2 2 2 0 Dihydrodipicolinate reductase, N-terminus Yae1_N PF09811.4 EGC40516.1 - 4.9e-09 35.5 2.0 4.9e-09 35.5 1.4 1.6 2 0 0 2 2 2 1 Essential protein Yae1, N terminal DUF843 PF05814.6 EGC40517.1 - 0.049 13.4 1.1 0.053 13.3 0.7 1.3 1 0 0 1 1 1 0 Baculovirus protein of unknown function (DUF843) OppC_N PF12911.2 EGC40517.1 - 0.06 12.7 5.4 0.14 11.5 0.2 2.1 2 0 0 2 2 2 0 N-terminal TM domain of oligopeptide transport permease C Ras PF00071.17 EGC40518.1 - 1.3e-13 50.6 0.9 3.7e-13 49.1 0.6 1.7 1 1 0 1 1 1 1 Ras family Miro PF08477.8 EGC40518.1 - 0.0045 17.4 0.3 0.01 16.3 0.1 1.8 2 0 0 2 2 2 1 Miro-like protein TP6A_N PF04406.9 EGC40518.1 - 0.011 15.3 0.5 0.031 13.9 0.3 1.8 1 0 0 1 1 1 0 Type IIB DNA topoisomerase EphA2_TM PF14575.1 EGC40519.1 - 0.013 15.8 0.2 0.023 15.0 0.1 1.4 1 0 0 1 1 1 0 Ephrin type-A receptor 2 transmembrane domain Herpes_gE PF02480.11 EGC40519.1 - 0.041 12.1 0.0 0.072 11.3 0.0 1.3 1 0 0 1 1 1 0 Alphaherpesvirus glycoprotein E Shisa PF13908.1 EGC40519.1 - 0.047 13.8 0.0 0.097 12.8 0.0 1.4 1 0 0 1 1 1 0 Wnt and FGF inhibitory regulator YbbR PF07949.7 EGC40519.1 - 0.11 12.6 4.1 9 6.5 0.8 3.1 2 0 0 2 2 2 0 YbbR-like protein FNIP PF05725.7 EGC40520.1 - 4.6e-56 186.5 35.4 6.8e-12 45.1 0.2 8.5 7 2 1 8 8 8 8 FNIP Repeat LRR_5 PF13306.1 EGC40520.1 - 0.0027 17.3 0.3 0.6 9.8 0.0 3.4 2 1 1 3 3 3 1 Leucine rich repeats (6 copies) zf-B_box PF00643.19 EGC40521.1 - 3.3e-07 30.0 3.7 6.2e-07 29.2 2.5 1.5 1 0 0 1 1 1 1 B-box zinc finger FNIP PF05725.7 EGC40521.1 - 3.6e-07 30.0 6.8 4.5e-06 26.5 0.7 3.6 3 1 1 4 4 4 2 FNIP Repeat zf-UBR PF02207.15 EGC40521.1 - 0.002 17.7 2.7 0.0054 16.4 1.9 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) DUF3086 PF11285.3 EGC40521.1 - 1.1 8.0 6.1 1.6 7.4 4.2 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF3086) CortBP2 PF09727.4 EGC40521.1 - 1.5 8.2 12.3 3.2 7.2 8.5 1.5 1 1 0 1 1 1 0 Cortactin-binding protein-2 Tnp_zf-ribbon_2 PF13842.1 EGC40521.1 - 1.6 9.2 5.8 4.1 7.8 4.0 1.8 1 0 0 1 1 1 0 DDE_Tnp_1-like zinc-ribbon Fucose_iso_N2 PF07882.7 EGC40521.1 - 1.9 8.0 7.8 0.27 10.8 1.2 1.9 1 1 1 2 2 2 0 L-fucose isomerase, second N-terminal domain DUF1342 PF07072.6 EGC40521.1 - 7 6.2 11.6 3.2 7.3 0.7 2.2 1 1 1 2 2 2 0 Protein of unknown function (DUF1342) Sec20 PF03908.8 EGC40521.1 - 8.6 6.1 13.8 0.51 10.0 2.4 3.0 1 1 2 3 3 3 0 Sec20 zf-B_box PF00643.19 EGC40522.1 - 2e-06 27.5 3.4 3.2e-06 26.9 2.3 1.3 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC40522.1 - 0.0088 15.7 2.4 0.021 14.5 1.6 1.6 1 1 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) V-ATPase_G PF03179.10 EGC40522.1 - 0.44 10.8 2.8 0.53 10.6 1.4 1.5 1 1 1 2 2 2 0 Vacuolar (H+)-ATPase G subunit FNIP PF05725.7 EGC40523.1 - 5.9e-13 48.5 19.6 4.5e-06 26.5 0.2 4.9 4 1 2 6 6 6 5 FNIP Repeat Ribosomal_L13 PF00572.13 EGC40524.1 - 2.2e-47 160.2 0.6 4e-47 159.4 0.4 1.4 1 0 0 1 1 1 1 Ribosomal protein L13 TPR_17 PF13431.1 EGC40525.1 - 4.8e-36 119.9 18.2 3.1e-06 26.9 0.0 9.4 9 0 0 9 9 9 7 Tetratricopeptide repeat TPR_11 PF13414.1 EGC40525.1 - 2.7e-12 46.1 18.4 0.011 15.3 0.1 7.7 9 0 0 9 9 9 6 TPR repeat LacI PF00356.16 EGC40526.1 - 0.48 10.0 0.0 0.48 10.0 0.0 3.4 3 0 0 3 3 3 0 Bacterial regulatory proteins, lacI family Rota_VP2 PF05087.7 EGC40526.1 - 5 4.9 34.5 2 6.2 22.2 1.4 1 1 1 2 2 2 0 Rotavirus VP2 protein EGF_2 PF07974.8 EGC40527.1 - 0.00017 21.6 20.1 0.00018 21.5 8.5 2.6 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.5 EGC40527.1 - 0.029 13.6 1.5 0.064 12.5 1.1 1.6 1 0 0 1 1 1 0 Transmembrane alpha-helix domain RasGEF PF00617.14 EGC40528.1 - 0.026 14.2 0.1 0.046 13.4 0.1 1.5 1 0 0 1 1 1 0 RasGEF domain Glyco_hydro_7 PF00840.15 EGC40528.1 - 0.062 11.6 0.4 0.077 11.3 0.3 1.1 1 0 0 1 1 1 0 Glycosyl hydrolase family 7 Ykof PF07615.6 EGC40528.1 - 0.14 12.3 0.3 0.87 9.7 0.0 2.3 2 1 0 2 2 2 0 YKOF-related Family EGF_2 PF07974.8 EGC40529.1 - 2.9e-05 24.1 18.1 0.00018 21.5 8.5 2.8 2 0 0 2 2 2 2 EGF-like domain SKG6 PF08693.5 EGC40529.1 - 0.02 14.1 1.9 0.038 13.3 1.3 1.5 1 0 0 1 1 1 0 Transmembrane alpha-helix domain MFS_1 PF07690.11 EGC40530.1 - 3.1e-66 223.5 52.3 4.3e-56 190.1 17.3 2.5 1 1 1 2 2 2 2 Major Facilitator Superfamily Sugar_tr PF00083.19 EGC40530.1 - 9.3e-18 64.0 8.4 6.9e-14 51.2 0.5 2.3 2 0 0 2 2 2 2 Sugar (and other) transporter MFS_2 PF13347.1 EGC40530.1 - 4.5e-14 51.6 27.9 8.5e-08 31.0 5.6 2.4 2 1 0 2 2 2 2 MFS/sugar transport protein OATP PF03137.15 EGC40530.1 - 0.00016 19.9 20.4 0.00042 18.5 0.1 3.4 2 1 1 3 3 3 3 Organic Anion Transporter Polypeptide (OATP) family MFS_3 PF05977.8 EGC40530.1 - 0.0024 16.0 23.6 0.013 13.6 1.9 3.5 2 2 2 4 4 4 2 Transmembrane secretion effector LacY_symp PF01306.14 EGC40530.1 - 0.0033 16.0 13.0 0.0033 16.0 9.0 2.6 2 1 0 2 2 2 1 LacY proton/sugar symporter Gly-zipper_Omp PF13488.1 EGC40530.1 - 0.16 11.6 3.1 0.53 9.9 2.2 1.9 1 0 0 1 1 1 0 Glycine zipper Pam17 PF08566.5 EGC40530.1 - 0.51 10.0 3.3 0.43 10.2 0.6 2.1 2 0 0 2 2 2 0 Mitochondrial import protein Pam17 DUF912 PF06024.7 EGC40531.1 - 1.3e-05 25.1 1.5 1.3e-05 25.1 1.0 3.1 2 1 0 2 2 2 1 Nucleopolyhedrovirus protein of unknown function (DUF912) Kei1 PF08552.6 EGC40531.1 - 0.0073 15.9 5.0 0.0073 15.9 3.5 4.9 1 1 1 2 2 1 1 Inositolphosphorylceramide synthase subunit Kei1 DUF3753 PF12575.3 EGC40531.1 - 0.0078 15.9 0.3 0.023 14.4 0.2 1.8 1 0 0 1 1 1 1 Protein of unknown function (DUF3753) MSC PF09402.5 EGC40531.1 - 0.0095 14.6 1.2 0.016 13.9 0.8 1.3 1 0 0 1 1 1 1 Man1-Src1p-C-terminal domain Amnionless PF14828.1 EGC40531.1 - 0.011 14.2 0.1 0.021 13.3 0.0 1.5 1 0 0 1 1 1 0 Amnionless Tmemb_9 PF05434.6 EGC40531.1 - 0.017 14.8 0.2 0.036 13.8 0.1 1.5 1 0 0 1 1 1 0 TMEM9 DUF4448 PF14610.1 EGC40531.1 - 0.018 14.5 0.1 0.018 14.5 0.1 3.0 2 2 0 3 3 3 0 Protein of unknown function (DUF4448) Baculo_E56 PF04639.7 EGC40531.1 - 0.04 12.5 1.0 0.086 11.4 0.7 1.5 1 0 0 1 1 1 0 Baculoviral E56 protein, specific to ODV envelope AIF_C PF14721.1 EGC40531.1 - 0.06 13.5 0.2 0.06 13.5 0.2 3.8 1 1 1 3 3 2 0 Apoptosis-inducing factor, mitochondrion-associated, C-term LRRC37AB_C PF14914.1 EGC40531.1 - 0.14 11.5 0.9 0.77 9.1 0.1 2.1 2 0 0 2 2 2 0 LRRC37A/B like protein 1 C-terminal domain RIC3 PF15361.1 EGC40531.1 - 0.3 11.3 0.0 0.3 11.3 0.0 3.7 1 1 1 3 3 2 0 Resistance to inhibitors of cholinesterase homologue 3 DUF2347 PF09804.4 EGC40531.1 - 7.3 5.7 11.0 0.63 9.2 1.6 2.7 2 1 0 2 2 2 0 Uncharacterized conserved protein (DUF2347) Rifin_STEVOR PF02009.11 EGC40531.1 - 7.5 6.1 18.7 0.05 13.2 5.0 2.6 1 1 0 2 2 2 0 Rifin/stevor family FNIP PF05725.7 EGC40532.1 - 1.9e-25 88.5 53.1 1.1e-09 38.1 0.4 9.7 8 0 0 8 8 8 6 FNIP Repeat MCPsignal PF00015.16 EGC40532.1 - 0.24 10.9 0.6 0.64 9.5 0.4 1.7 1 0 0 1 1 1 0 Methyl-accepting chemotaxis protein (MCP) signalling domain LRR_4 PF12799.2 EGC40533.1 - 1.6e-12 46.7 48.4 0.0075 15.8 0.0 7.8 4 2 3 8 8 8 6 Leucine Rich repeats (2 copies) LRR_6 PF13516.1 EGC40533.1 - 2.4e-12 45.5 45.1 0.021 14.8 0.0 11.5 12 0 0 12 12 12 6 Leucine Rich repeat LRR_7 PF13504.1 EGC40533.1 - 8.6e-05 22.1 21.0 5.8 7.5 0.0 9.5 11 0 0 11 11 11 1 Leucine rich repeat LRR_1 PF00560.28 EGC40533.1 - 0.00034 20.2 35.1 0.41 10.8 0.3 10.0 11 0 0 11 11 11 3 Leucine Rich Repeat LRR_8 PF13855.1 EGC40533.1 - 0.00056 19.6 40.4 0.0016 18.1 5.8 6.6 3 2 3 6 6 6 4 Leucine rich repeat F-box-like PF12937.2 EGC40533.1 - 0.0042 16.7 0.2 0.0098 15.6 0.1 1.6 1 0 0 1 1 1 1 F-box-like LRR_8 PF13855.1 EGC40536.1 - 0.0031 17.2 1.6 0.0031 17.2 1.1 4.6 5 0 0 5 5 5 2 Leucine rich repeat Stress-antifung PF01657.12 EGC40537.1 - 0.15 12.3 0.5 0.82 10.0 0.0 2.3 2 0 0 2 2 2 0 Salt stress response/antifungal Arm PF00514.18 EGC40538.1 - 1e-14 53.7 7.5 9.5e-09 34.7 0.2 7.8 8 1 1 9 9 9 2 Armadillo/beta-catenin-like repeat RICTOR_V PF14668.1 EGC40538.1 - 2e-05 24.4 0.2 1.4 8.8 0.0 4.0 2 1 1 3 3 3 3 Rapamycin-insensitive companion of mTOR, domain 5 Arm_2 PF04826.8 EGC40539.1 - 2.7e-05 23.3 0.2 2.7e-05 23.3 0.1 1.6 2 0 0 2 2 2 1 Armadillo-like Arm PF00514.18 EGC40539.1 - 0.0033 17.2 0.0 0.28 11.0 0.0 2.9 3 0 0 3 3 3 1 Armadillo/beta-catenin-like repeat DUF383 PF04063.9 EGC40539.1 - 0.053 13.0 0.6 1.9 7.9 0.1 2.2 1 1 1 2 2 2 0 Domain of unknown function (DUF383) Med24_N PF11277.3 EGC40540.1 - 1.5e-10 39.3 0.0 1.5e-10 39.3 0.0 4.5 4 1 1 5 5 5 2 Mediator complex subunit 24 N-terminal SSP160 PF06933.6 EGC40542.1 - 0.085 10.8 16.7 0.17 9.8 11.6 1.4 1 0 0 1 1 1 0 Special lobe-specific silk protein SSP160 Mucin PF01456.12 EGC40542.1 - 0.63 9.8 30.0 1.3 8.7 20.8 1.5 1 0 0 1 1 1 0 Mucin-like glycoprotein UQ_con PF00179.21 EGC40543.1 - 3.4e-42 143.1 0.1 5.6e-42 142.5 0.1 1.3 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme VWA_2 PF13519.1 EGC40543.1 - 7.7e-13 48.9 0.0 2.7e-12 47.1 0.0 1.7 2 0 0 2 2 2 1 von Willebrand factor type A domain Rad60-SLD PF11976.3 EGC40543.1 - 4.5e-06 26.2 0.5 9.8e-06 25.1 0.3 1.5 1 0 0 1 1 1 1 Ubiquitin-2 like Rad60 SUMO-like Prok-E2_B PF14461.1 EGC40543.1 - 7.9e-05 22.4 0.0 0.00017 21.3 0.0 1.6 1 0 0 1 1 1 1 Prokaryotic E2 family B TUG-UBL1 PF11470.3 EGC40543.1 - 0.00027 20.7 0.1 0.00065 19.5 0.1 1.7 1 0 0 1 1 1 1 GLUT4 regulating protein TUG VWA PF00092.23 EGC40543.1 - 0.0011 18.7 0.0 0.004 16.8 0.0 2.0 2 1 0 2 2 2 1 von Willebrand factor type A domain ubiquitin PF00240.18 EGC40543.1 - 0.0012 18.2 0.1 0.0027 17.0 0.1 1.6 1 0 0 1 1 1 1 Ubiquitin family RWD PF05773.17 EGC40543.1 - 0.0014 18.4 0.0 0.0039 17.0 0.0 1.7 1 0 0 1 1 1 1 RWD domain FERM_N PF09379.5 EGC40543.1 - 0.0074 16.3 0.2 0.015 15.3 0.1 1.5 1 0 0 1 1 1 1 FERM N-terminal domain YukD PF08817.5 EGC40543.1 - 0.017 15.6 0.0 0.13 12.8 0.0 2.5 2 0 0 2 2 2 0 WXG100 protein secretion system (Wss), protein YukD VWA_3 PF13768.1 EGC40543.1 - 0.027 14.1 0.0 1.6 8.4 0.0 2.4 2 0 0 2 2 2 0 von Willebrand factor type A domain UEV PF05743.8 EGC40543.1 - 0.093 12.4 0.1 0.19 11.4 0.1 1.5 1 0 0 1 1 1 0 UEV domain DUF3357 PF11837.3 EGC40544.1 - 0.00047 19.9 13.0 0.68 9.8 0.3 4.6 1 1 4 5 5 5 4 Domain of unknown function (DUF3357) DUF4064 PF13273.1 EGC40544.1 - 0.0034 17.4 7.8 1.6 8.8 0.0 3.5 2 1 2 4 4 4 2 Protein of unknown function (DUF4064) EphA2_TM PF14575.1 EGC40544.1 - 0.0069 16.7 11.2 3.1 8.2 0.1 5.6 2 2 3 5 5 5 1 Ephrin type-A receptor 2 transmembrane domain DUF3397 PF11877.3 EGC40544.1 - 0.014 15.4 5.6 2.4 8.1 0.2 3.6 4 0 0 4 4 4 0 Protein of unknown function (DUF3397) Sex_peptide PF08138.6 EGC40544.1 - 0.17 11.7 0.0 4.3 7.2 0.0 3.1 3 0 0 3 3 3 0 Sex peptide (SP) family Plant_vir_prot PF01307.12 EGC40544.1 - 0.3 10.8 26.6 0.31 10.7 1.0 5.2 2 2 4 6 6 6 0 Plant viral movement protein DUF4401 PF14351.1 EGC40544.1 - 0.37 9.7 12.0 0.71 8.8 4.8 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF4401) DUF1616 PF07760.6 EGC40544.1 - 0.55 9.3 8.8 2.8 6.9 1.1 2.3 1 1 0 2 2 2 0 Protein of unknown function (DUF1616) Polysacc_synt PF01943.12 EGC40544.1 - 0.56 9.4 14.6 0.87 8.8 1.9 3.0 2 2 0 2 2 2 0 Polysaccharide biosynthesis protein DUF3619 PF12279.3 EGC40544.1 - 1.1 9.3 13.1 1.5 8.9 0.6 3.6 1 1 2 4 4 4 0 Protein of unknown function (DUF3619) NMN_transporter PF04973.7 EGC40544.1 - 1.7 8.1 6.0 11 5.3 0.2 3.0 1 1 1 3 3 3 0 Nicotinamide mononucleotide transporter Glyco_hydro_88 PF07470.8 EGC40544.1 - 3.2 6.7 8.8 7.1 5.5 0.1 3.4 1 1 3 4 4 4 0 Glycosyl Hydrolase Family 88 LRRNT_2 PF08263.7 EGC40544.1 - 4 7.4 14.4 12 5.9 0.3 3.5 3 0 0 3 3 3 0 Leucine rich repeat N-terminal domain Cyto_ox_2 PF02322.10 EGC40544.1 - 4.5 6.3 11.3 5.5 6.0 1.8 2.0 1 1 1 2 2 2 0 Cytochrome oxidase subunit II MARVEL PF01284.18 EGC40544.1 - 4.9 6.9 9.0 2e+02 1.7 6.0 2.9 1 1 0 1 1 1 0 Membrane-associating domain Colicin_V PF02674.11 EGC40544.1 - 9.5 6.0 13.6 4.1 7.2 0.5 3.5 1 1 2 3 3 3 0 Colicin V production protein UCH PF00443.24 EGC40545.1 - 1.4e-39 135.8 50.1 1.4e-39 135.8 34.7 3.8 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase UCH_1 PF13423.1 EGC40545.1 - 6.2e-13 48.8 41.4 6.2e-13 48.8 28.7 5.7 3 1 0 3 3 3 1 Ubiquitin carboxyl-terminal hydrolase zf-C4_ClpX PF06689.8 EGC40545.1 - 0.012 15.0 0.6 5.4 6.6 0.1 2.7 2 0 0 2 2 2 0 ClpX C4-type zinc finger UPF0118 PF01594.11 EGC40545.1 - 7.1 5.5 5.8 3.4 6.5 1.8 1.9 2 0 0 2 2 2 0 Domain of unknown function DUF20 K1 PF02960.9 EGC40546.1 - 0.0048 16.9 2.9 0.0068 16.4 1.3 1.9 1 1 0 1 1 1 1 K1 glycoprotein DUF373 PF04123.8 EGC40546.1 - 1.7 7.5 15.5 0.26 10.2 6.1 2.1 1 1 1 2 2 2 0 Domain of unknown function (DUF373) CcmD PF04995.9 EGC40546.1 - 3.5 7.4 5.1 12 5.7 2.8 2.4 2 0 0 2 2 2 0 Heme exporter protein D (CcmD) adh_short PF00106.20 EGC40547.1 - 2.9e-22 79.3 0.0 3.7e-22 79.0 0.0 1.1 1 0 0 1 1 1 1 short chain dehydrogenase adh_short_C2 PF13561.1 EGC40547.1 - 1.3e-15 57.7 0.0 1.7e-15 57.4 0.0 1.1 1 0 0 1 1 1 1 Enoyl-(Acyl carrier protein) reductase KR PF08659.5 EGC40547.1 - 2.7e-05 23.9 0.0 4.5e-05 23.1 0.0 1.2 1 0 0 1 1 1 1 KR domain DUF1776 PF08643.5 EGC40547.1 - 0.00032 19.9 0.1 0.00054 19.1 0.0 1.3 1 1 0 1 1 1 1 Fungal family of unknown function (DUF1776) NAD_binding_10 PF13460.1 EGC40547.1 - 0.15 12.0 0.0 0.24 11.3 0.0 1.4 1 1 0 1 1 1 0 NADH(P)-binding FNIP PF05725.7 EGC40548.1 - 1.4e-100 329.0 44.5 5.7e-14 51.7 0.2 8.2 6 1 1 8 8 8 8 FNIP Repeat DUF1769 PF08588.5 EGC40548.1 - 1.5e-05 24.8 30.2 4.2 7.3 0.0 11.1 2 2 10 12 12 12 6 Protein of unknown function (DUF1769) PH PF00169.24 EGC40549.1 - 1.9e-22 79.4 0.2 1.9e-22 79.4 0.1 3.1 3 0 0 3 3 3 1 PH domain PTEN_C2 PF10409.4 EGC40549.1 - 2.1e-22 79.2 0.0 4.6e-22 78.1 0.0 1.6 1 0 0 1 1 1 1 C2 domain of PTEN tumour-suppressor protein PH_11 PF15413.1 EGC40549.1 - 4.3e-10 39.8 1.3 4.3e-10 39.8 0.9 4.8 3 2 1 4 4 4 1 Pleckstrin homology domain PH_8 PF15409.1 EGC40549.1 - 1.1e-05 25.3 0.0 3.4e-05 23.8 0.0 1.9 1 0 0 1 1 1 1 Pleckstrin homology domain Y_phosphatase PF00102.22 EGC40549.1 - 1.1e-05 24.8 0.0 2.6e-05 23.6 0.0 1.6 1 0 0 1 1 1 1 Protein-tyrosine phosphatase Y_phosphatase3 PF13350.1 EGC40549.1 - 7.3e-05 23.0 0.0 0.00028 21.1 0.0 2.0 1 0 0 1 1 1 1 Tyrosine phosphatase family DSPc PF00782.15 EGC40549.1 - 0.00018 21.0 3.0 0.0002 20.9 0.0 2.7 3 0 0 3 3 3 1 Dual specificity phosphatase, catalytic domain PH_3 PF14593.1 EGC40549.1 - 0.004 17.0 1.1 0.014 15.2 0.1 2.4 1 1 1 2 2 2 1 PH domain zf-Sec23_Sec24 PF04810.10 EGC40550.1 - 3.8 7.1 7.3 0.57 9.7 1.9 2.0 2 0 0 2 2 2 0 Sec23/Sec24 zinc finger FNIP PF05725.7 EGC40551.1 - 2.4e-115 376.2 46.0 3.4e-17 62.1 0.4 10.6 8 3 2 10 10 10 10 FNIP Repeat ChaB PF06150.7 EGC40551.1 - 0.16 11.8 0.0 0.59 9.9 0.0 2.0 1 1 1 2 2 2 0 ChaB LRR_5 PF13306.1 EGC40551.1 - 0.42 10.3 2.7 7.7 6.2 0.1 3.5 3 2 0 3 3 3 0 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC40552.1 - 9.9e-57 188.6 52.4 3.6e-10 39.6 0.0 11.1 4 4 5 11 11 11 10 FNIP Repeat LRR_5 PF13306.1 EGC40552.1 - 8.9e-08 31.9 12.0 1.6e-05 24.6 0.0 4.1 4 1 0 4 4 4 3 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC40553.1 - 1.5e-96 316.1 41.7 2.4e-16 59.4 0.3 8.3 4 2 5 10 10 10 10 FNIP Repeat DUF1769 PF08588.5 EGC40553.1 - 1.6e-05 24.7 20.7 2.1 8.3 0.1 8.9 4 3 7 11 11 11 3 Protein of unknown function (DUF1769) MerC PF03203.9 EGC40553.1 - 0.089 13.1 0.0 26 5.2 0.0 3.7 2 1 1 4 4 4 0 MerC mercury resistance protein Phage_min_tail PF05939.8 EGC40553.1 - 0.13 12.2 0.0 53 3.8 0.0 4.6 5 2 2 7 7 7 0 Phage minor tail protein BPD_transp_1 PF00528.17 EGC40553.1 - 1.9 7.9 7.2 1.6 8.1 0.3 3.7 2 2 1 3 3 3 0 Binding-protein-dependent transport system inner membrane component zf-HC5HC2H PF13771.1 EGC40554.1 - 0.35 11.0 2.3 1.9 8.6 1.6 1.9 1 1 0 1 1 1 0 PHD-like zinc-binding domain FNIP PF05725.7 EGC40555.1 - 7.8e-106 345.8 50.2 7.2e-16 57.8 0.3 8.3 2 1 4 10 10 10 9 FNIP Repeat FNIP PF05725.7 EGC40556.1 - 2.7e-18 65.6 19.6 1.9e-05 24.4 0.0 5.7 3 1 1 4 4 4 4 FNIP Repeat zf-B_box PF00643.19 EGC40556.1 - 2.8e-05 23.9 3.9 5.5e-05 22.9 2.7 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC40556.1 - 0.13 11.9 2.3 0.3 10.8 1.6 1.6 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) bZIP_C PF12498.3 EGC40556.1 - 2.6 9.2 7.4 0.38 12.0 1.2 2.2 1 1 1 2 2 2 0 Basic leucine-zipper C terminal FNIP PF05725.7 EGC40557.1 - 0.00049 19.9 0.6 0.0011 18.8 0.4 1.7 1 0 0 1 1 1 1 FNIP Repeat TPR_17 PF13431.1 EGC40558.1 - 0.093 12.9 0.7 0.59 10.4 0.1 2.7 2 0 0 2 2 2 0 Tetratricopeptide repeat FNIP PF05725.7 EGC40559.1 - 2e-63 210.0 53.8 1.2e-10 41.1 0.4 10.6 7 4 3 10 10 10 10 FNIP Repeat Maf1 PF09174.5 EGC40559.1 - 0.00036 20.4 0.0 0.00069 19.5 0.0 1.4 1 0 0 1 1 1 1 Maf1 regulator LRR_5 PF13306.1 EGC40559.1 - 0.0094 15.6 6.8 0.31 10.7 0.7 4.4 2 2 2 4 4 4 1 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC40560.1 - 1.2e-58 194.7 58.8 2.9e-10 39.9 0.1 10.9 6 2 6 13 13 13 12 FNIP Repeat FNIP PF05725.7 EGC40562.1 - 1.3e-50 169.0 53.4 1.4e-10 40.9 2.0 9.1 6 3 3 9 9 9 8 FNIP Repeat LRR_2 PF07723.8 EGC40562.1 - 0.045 14.2 0.2 49 4.6 0.0 4.1 3 0 0 3 3 3 0 Leucine Rich Repeat FNIP PF05725.7 EGC40563.1 - 1.6e-95 312.8 87.4 8.9e-12 44.7 0.7 15.4 9 5 5 14 14 14 14 FNIP Repeat LRR_2 PF07723.8 EGC40563.1 - 0.011 16.2 0.7 98 3.7 0.0 4.8 4 0 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.7 EGC40564.1 - 4.2e-89 292.2 79.7 2.8e-11 43.1 1.5 15.1 7 4 6 16 16 16 16 FNIP Repeat LRR_2 PF07723.8 EGC40564.1 - 0.11 12.9 3.6 1.3e+02 3.2 0.0 5.0 4 0 0 4 4 4 0 Leucine Rich Repeat FNIP PF05725.7 EGC40565.1 - 3.4e-71 234.9 73.5 2.5e-11 43.3 1.5 11.2 5 4 6 12 12 12 11 FNIP Repeat FNIP PF05725.7 EGC40566.1 - 6.7e-62 205.2 52.0 6.5e-13 48.4 0.0 10.4 4 2 6 11 11 11 10 FNIP Repeat FNIP PF05725.7 EGC40567.1 - 9.1e-45 150.3 69.6 1.3e-09 37.8 1.0 8.9 2 1 8 11 11 11 10 FNIP Repeat PROL5-SMR PF15621.1 EGC40567.1 - 9.5 6.6 11.2 5.3 7.5 0.2 2.8 2 1 1 3 3 3 0 Proline-rich submaxillary gland androgen-regulated family FNIP PF05725.7 EGC40568.1 - 2.6e-64 212.9 102.3 8.4e-09 35.2 1.3 12.2 2 2 14 16 16 16 16 FNIP Repeat FNIP PF05725.7 EGC40569.1 - 2.3e-58 193.9 79.2 1.5e-12 47.2 0.1 11.9 2 2 12 15 15 15 13 FNIP Repeat CG-1 PF03859.11 EGC40570.1 - 0.054 13.0 4.3 0.047 13.2 0.6 2.7 3 0 0 3 3 3 0 CG-1 domain PRK PF00485.13 EGC40571.1 - 5.9e-50 169.5 0.1 7e-50 169.2 0.0 1.0 1 0 0 1 1 1 1 Phosphoribulokinase / Uridine kinase family AAA_17 PF13207.1 EGC40571.1 - 3.4e-11 44.0 0.1 7.1e-11 42.9 0.1 1.5 1 1 0 1 1 1 1 AAA domain AAA_18 PF13238.1 EGC40571.1 - 1.2e-09 38.5 0.0 2.2e-09 37.6 0.0 1.4 1 0 0 1 1 1 1 AAA domain CoaE PF01121.15 EGC40571.1 - 2.8e-06 26.8 0.1 5.7e-05 22.5 0.1 2.1 1 1 0 1 1 1 1 Dephospho-CoA kinase MobB PF03205.9 EGC40571.1 - 8.8e-06 25.4 1.0 0.00058 19.5 0.5 2.6 1 1 0 1 1 1 1 Molybdopterin guanine dinucleotide synthesis protein B AAA_33 PF13671.1 EGC40571.1 - 8.5e-05 22.4 0.0 0.00013 21.8 0.0 1.4 1 1 0 1 1 1 1 AAA domain Zeta_toxin PF06414.7 EGC40571.1 - 0.00057 19.0 0.0 0.0011 18.0 0.0 1.5 2 0 0 2 2 2 1 Zeta toxin Pox_A32 PF04665.7 EGC40571.1 - 0.0021 17.3 0.0 0.004 16.4 0.0 1.4 1 0 0 1 1 1 1 Poxvirus A32 protein T2SE PF00437.15 EGC40571.1 - 0.0026 16.7 0.0 0.0048 15.8 0.0 1.3 1 0 0 1 1 1 1 Type II/IV secretion system protein AAA_14 PF13173.1 EGC40571.1 - 0.0027 17.5 0.3 0.01 15.7 0.2 2.0 1 1 0 1 1 1 1 AAA domain APS_kinase PF01583.15 EGC40571.1 - 0.016 14.8 0.0 0.052 13.2 0.0 1.8 2 0 0 2 2 2 0 Adenylylsulphate kinase AAA_28 PF13521.1 EGC40571.1 - 0.021 14.7 0.0 0.036 14.0 0.0 1.5 1 0 0 1 1 1 0 AAA domain NTPase_1 PF03266.10 EGC40571.1 - 0.041 13.6 0.1 0.11 12.2 0.0 1.7 2 0 0 2 2 2 0 NTPase cobW PF02492.14 EGC40571.1 - 0.058 12.8 0.0 0.08 12.3 0.0 1.3 1 0 0 1 1 1 0 CobW/HypB/UreG, nucleotide-binding domain Thymidylate_kin PF02223.12 EGC40571.1 - 0.064 12.6 0.2 1.9 7.8 0.0 2.2 2 0 0 2 2 2 0 Thymidylate kinase UPF0079 PF02367.12 EGC40571.1 - 0.084 12.5 0.0 0.86 9.2 0.0 2.1 2 0 0 2 2 2 0 Uncharacterised P-loop hydrolase UPF0079 AAA_16 PF13191.1 EGC40571.1 - 0.084 12.8 0.0 0.17 11.8 0.0 1.5 2 0 0 2 2 2 0 AAA ATPase domain DUF87 PF01935.12 EGC40571.1 - 0.09 12.5 0.3 0.25 11.1 0.2 1.9 1 1 0 1 1 1 0 Domain of unknown function DUF87 ArgK PF03308.11 EGC40571.1 - 0.098 11.4 0.0 0.27 9.9 0.0 1.7 2 0 0 2 2 2 0 ArgK protein DUF2529 PF10740.4 EGC40572.1 - 0.022 14.1 0.1 0.026 13.9 0.1 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF2529) ATP-cone PF03477.11 EGC40572.1 - 0.086 13.2 0.3 0.1 13.0 0.2 1.1 1 0 0 1 1 1 0 ATP cone domain Ribosomal_L12 PF00542.14 EGC40574.1 - 5.9e-18 64.6 6.2 5.9e-18 64.6 4.3 1.9 2 0 0 2 2 2 1 Ribosomal protein L7/L12 C-terminal domain SpoVIF PF14069.1 EGC40574.1 - 0.043 13.5 1.8 1.3 8.7 0.1 2.5 2 1 0 2 2 2 0 Stage VI sporulation protein F DUF3138 PF11336.3 EGC40574.1 - 0.12 10.4 0.2 0.16 10.1 0.2 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3138) NUFIP1 PF10453.4 EGC40575.1 - 1.5e-14 53.1 12.5 1.5e-14 53.1 8.6 5.9 7 1 0 7 7 7 1 Nuclear fragile X mental retardation-interacting protein 1 (NUFIP1) eIF-3_zeta PF05091.7 EGC40576.1 - 7.2e-161 536.3 5.6 8.4e-161 536.0 3.9 1.0 1 0 0 1 1 1 1 Eukaryotic translation initiation factor 3 subunit 7 (eIF-3) Aldo_ket_red PF00248.16 EGC40577.1 - 1.8e-05 23.7 0.3 2.9e-05 23.0 0.2 1.4 1 0 0 1 1 1 1 Aldo/keto reductase family BTB_2 PF02214.17 EGC40578.1 - 5.1e-14 52.2 0.5 1.6e-09 37.8 0.3 2.9 2 1 0 2 2 2 2 BTB/POZ domain DUSP PF06337.7 EGC40578.1 - 2.1e-08 34.4 13.0 2.2e-08 34.4 0.0 3.5 2 1 0 2 2 2 1 DUSP domain BTB PF00651.26 EGC40578.1 - 0.014 15.3 0.0 0.034 14.1 0.0 1.7 1 0 0 1 1 1 0 BTB/POZ domain FNIP PF05725.7 EGC40579.1 - 7.9e-72 236.9 27.7 7.1e-13 48.2 1.2 7.0 3 3 3 7 7 7 7 FNIP Repeat LRR_5 PF13306.1 EGC40579.1 - 2e-05 24.3 0.1 0.00065 19.4 0.0 2.5 1 1 0 2 2 2 1 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC40580.1 - 2.3e-90 296.3 131.0 3.2e-05 23.7 0.0 24.4 11 2 18 31 31 31 30 FNIP Repeat zf-B_box PF00643.19 EGC40580.1 - 9.8e-05 22.1 5.5 0.00018 21.2 3.8 1.5 1 0 0 1 1 1 1 B-box zinc finger zf-UBR PF02207.15 EGC40580.1 - 0.039 13.6 3.0 0.082 12.6 2.1 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) FNIP PF05725.7 EGC40581.1 - 1.7e-48 162.3 60.6 1.3e-07 31.4 0.4 10.7 4 2 10 14 14 14 14 FNIP Repeat LRR_5 PF13306.1 EGC40581.1 - 1 9.0 10.5 0.25 11.0 0.6 3.9 2 2 1 3 3 3 0 Leucine rich repeats (6 copies) FNIP PF05725.7 EGC40582.1 - 1.5e-34 117.7 61.0 1.7e-06 27.8 0.1 13.4 6 3 9 16 16 16 15 FNIP Repeat zf-B_box PF00643.19 EGC40582.1 - 0.00017 21.3 5.6 0.0003 20.5 3.9 1.4 1 0 0 1 1 1 1 B-box zinc finger Thaumatin PF00314.12 EGC40582.1 - 0.012 15.0 0.1 9 5.6 0.0 4.0 3 0 0 3 3 3 0 Thaumatin family zf-UBR PF02207.15 EGC40582.1 - 0.32 10.7 3.0 0.66 9.7 2.1 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) zf-B_box PF00643.19 EGC40583.1 - 6.7e-06 25.8 3.2 6.7e-06 25.8 2.2 1.6 2 0 0 2 2 2 1 B-box zinc finger zf-UBR PF02207.15 EGC40583.1 - 0.0048 16.6 1.9 0.012 15.3 1.3 1.7 1 0 0 1 1 1 1 Putative zinc finger in N-recognin (UBR box) Sec23_trunk PF04811.10 EGC40583.1 - 0.018 14.4 0.2 0.031 13.6 0.1 1.3 1 0 0 1 1 1 0 Sec23/Sec24 trunk domain PHF5 PF03660.9 EGC40583.1 - 0.046 13.7 0.9 0.086 12.9 0.7 1.4 1 0 0 1 1 1 0 PHF5-like protein PDZ_1 PF12812.2 EGC40583.1 - 0.68 9.8 4.7 7.5 6.5 0.1 3.2 2 1 1 3 3 3 0 PDZ-like domain DUF1241 PF06840.6 EGC40583.1 - 0.99 8.6 11.8 0.23 10.6 3.6 2.6 1 1 0 2 2 2 0 Protein of unknown function (DUF1241) PBP_dimer PF03717.10 EGC40583.1 - 5.8 6.9 12.8 2e+02 1.9 8.9 2.1 1 1 0 1 1 1 0 Penicillin-binding Protein dimerisation domain zf-B_box PF00643.19 EGC40584.1 - 0.00016 21.5 3.4 0.00024 20.9 2.4 1.3 1 0 0 1 1 1 1 B-box zinc finger Acyl-CoA_ox_N PF14749.1 EGC40584.1 - 0.058 13.6 1.3 0.08 13.2 0.9 1.3 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal zf-UBR PF02207.15 EGC40584.1 - 0.068 12.9 2.4 0.12 12.1 1.7 1.4 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Fe_hyd_lg_C PF02906.9 EGC40584.1 - 6.6 5.9 6.7 0.59 9.3 0.6 2.0 2 1 0 2 2 2 0 Iron only hydrogenase large subunit, C-terminal domain FNIP PF05725.7 EGC40585.1 - 7.7e-76 249.8 107.0 5.9e-07 29.3 0.1 18.7 8 3 3 19 19 19 18 FNIP Repeat zf-B_box PF00643.19 EGC40585.1 - 1.1e-05 25.2 3.0 1.9e-05 24.4 2.1 1.4 1 0 0 1 1 1 1 B-box zinc finger PPR_2 PF13041.1 EGC40585.1 - 0.0041 17.0 0.9 17 5.4 0.0 4.6 4 0 0 4 4 4 1 PPR repeat family EFG_IV PF03764.13 EGC40585.1 - 0.15 11.6 0.6 0.31 10.6 0.4 1.5 1 0 0 1 1 1 0 Elongation factor G, domain IV zf-UBR PF02207.15 EGC40585.1 - 0.18 11.5 2.1 0.4 10.4 1.5 1.5 1 0 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) Orbi_VP5 PF00901.12 EGC40585.1 - 0.57 8.3 7.4 0.84 7.7 5.2 1.1 1 0 0 1 1 1 0 Orbivirus outer capsid protein VP5 TFIID_30kDa PF03540.8 EGC40585.1 - 1.1 9.0 5.0 37 4.2 0.1 5.6 6 0 0 6 6 6 0 Transcription initiation factor TFIID 23-30kDa subunit DUF3186 PF11382.3 EGC40585.1 - 2.1 7.4 4.8 3 6.8 3.3 1.1 1 0 0 1 1 1 0 Protein of unknown function (DUF3186) FNIP PF05725.7 EGC40586.1 - 1.3e-07 31.4 19.9 7.9e-07 28.9 1.3 4.4 3 1 1 5 5 5 2 FNIP Repeat zf-B_box PF00643.19 EGC40586.1 - 1.9e-06 27.6 4.7 3.9e-06 26.6 3.2 1.5 1 0 0 1 1 1 1 B-box zinc finger Heme_oxygenase PF01126.15 EGC40586.1 - 0.027 14.0 0.2 0.052 13.1 0.1 1.4 1 0 0 1 1 1 0 Heme oxygenase Acyl-CoA_ox_N PF14749.1 EGC40586.1 - 0.086 13.1 1.5 0.18 12.1 1.1 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal zf-UBR PF02207.15 EGC40586.1 - 0.13 11.9 3.3 0.33 10.6 2.3 1.7 1 1 0 1 1 1 0 Putative zinc finger in N-recognin (UBR box) FNIP PF05725.7 EGC40587.1 - 1.3e-38 130.6 29.7 2.5e-11 43.3 0.4 6.4 6 0 0 6 6 6 5 FNIP Repeat FNIP PF05725.7 EGC40588.1 - 3.8e-07 29.9 0.2 9.9e-07 28.6 0.0 1.7 2 0 0 2 2 2 1 FNIP Repeat RasGAP PF00616.14 EGC40589.1 - 2.7e-41 141.4 0.0 2.7e-41 141.4 0.0 4.2 3 1 2 5 5 5 1 GTPase-activator protein for Ras-like GTPase DUF547 PF04784.9 EGC40589.1 - 1.1e-20 73.6 0.2 1.3e-19 70.2 0.0 2.9 3 0 0 3 3 3 1 Protein of unknown function, DUF547 UQ_con PF00179.21 EGC40591.1 - 4.1e-37 126.7 0.3 4.6e-37 126.5 0.2 1.0 1 0 0 1 1 1 1 Ubiquitin-conjugating enzyme Prok-E2_B PF14461.1 EGC40591.1 - 0.0068 16.1 0.0 0.0093 15.7 0.0 1.2 1 0 0 1 1 1 1 Prokaryotic E2 family B zf-C3HC4_3 PF13920.1 EGC40592.1 - 6.3e-07 28.9 8.9 1.2e-06 28.1 6.2 1.4 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4 PF00097.20 EGC40592.1 - 2.2e-06 27.1 11.0 5.1e-06 26.0 7.6 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_2 PF13923.1 EGC40592.1 - 2.6e-06 27.3 11.0 5.1e-06 26.4 7.6 1.5 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-RING_2 PF13639.1 EGC40592.1 - 5.5e-06 26.1 8.5 1e-05 25.2 5.9 1.5 1 0 0 1 1 1 1 Ring finger domain zf-RING_5 PF14634.1 EGC40592.1 - 0.00028 20.5 10.8 0.00063 19.4 7.5 1.6 1 0 0 1 1 1 1 zinc-RING finger domain zf-RING_UBOX PF13445.1 EGC40592.1 - 0.00042 19.9 4.7 0.0024 17.5 3.3 2.5 1 0 0 1 1 1 1 RING-type zinc-finger zf-rbx1 PF12678.2 EGC40592.1 - 0.0048 16.9 3.2 0.015 15.3 2.2 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-RING_6 PF14835.1 EGC40592.1 - 0.0093 15.7 3.4 0.021 14.5 2.4 1.6 1 0 0 1 1 1 1 zf-RING of BARD1-type protein zf-Apc11 PF12861.2 EGC40592.1 - 0.04 13.7 3.2 0.059 13.2 1.3 1.9 2 0 0 2 2 2 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-C3HC4_4 PF15227.1 EGC40592.1 - 0.043 13.6 8.4 0.1 12.4 5.8 1.7 1 0 0 1 1 1 0 zinc finger of C3HC4-type, RING zf-RING_4 PF14570.1 EGC40592.1 - 0.37 10.4 9.5 0.99 9.0 6.6 1.8 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-Nse PF11789.3 EGC40592.1 - 0.72 9.4 6.3 2.3 7.8 4.3 1.9 1 0 0 1 1 1 0 Zinc-finger of the MIZ type in Nse subunit SUI1 PF01253.17 EGC40593.1 - 8.5e-24 83.1 0.7 1.2e-23 82.7 0.5 1.1 1 0 0 1 1 1 1 Translation initiation factor SUI1 BRCT PF00533.21 EGC40594.1 - 9.9e-08 32.0 0.6 9.9e-08 32.0 0.4 2.7 3 0 0 3 3 3 1 BRCA1 C Terminus (BRCT) domain PTCB-BRCT PF12738.2 EGC40594.1 - 0.021 14.6 0.1 0.17 11.7 0.0 2.5 2 0 0 2 2 2 0 twin BRCT domain Synaptobrevin PF00957.16 EGC40595.1 - 4e-05 23.1 2.7 8e-05 22.1 1.8 1.5 1 0 0 1 1 1 1 Synaptobrevin Peptidase_S49_N PF08496.5 EGC40595.1 - 0.00042 20.1 1.8 0.00042 20.1 1.2 1.8 2 0 0 2 2 2 1 Peptidase family S49 N-terminal WD40 PF00400.27 EGC40595.1 - 0.0021 17.8 1.7 13 5.9 0.0 5.1 5 0 0 5 5 5 1 WD domain, G-beta repeat FAM176 PF14851.1 EGC40595.1 - 0.17 11.5 4.3 2.6 7.7 0.5 2.5 2 0 0 2 2 2 0 FAM176 family Glycos_transf_2 PF00535.21 EGC40596.1 - 2.8e-24 85.6 4.0 2.8e-24 85.6 2.8 2.5 3 0 0 3 3 3 1 Glycosyl transferase family 2 Glyco_tranf_2_2 PF10111.4 EGC40596.1 - 1.4e-18 66.9 12.3 3.7e-18 65.6 3.0 2.3 2 0 0 2 2 2 2 Glycosyltransferase like family 2 Glyco_tranf_2_3 PF13641.1 EGC40596.1 - 3.4e-08 33.5 0.0 8.5e-08 32.2 0.0 1.6 1 1 0 1 1 1 1 Glycosyltransferase like family 2 Glyco_transf_7C PF02709.9 EGC40596.1 - 2.5e-05 23.6 0.5 6.7e-05 22.2 0.3 1.7 1 0 0 1 1 1 1 N-terminal domain of galactosyltransferase Glyco_tranf_2_4 PF13704.1 EGC40596.1 - 0.028 14.7 2.6 0.049 13.9 0.4 2.3 1 1 1 2 2 2 0 Glycosyl transferase family 2 Scramblase PF03803.10 EGC40597.1 - 2.6e-19 69.1 0.6 6.5e-09 35.1 0.2 2.1 2 0 0 2 2 2 2 Scramblase FNIP PF05725.7 EGC40598.1 - 1.5e-112 367.2 92.8 1.7e-12 47.0 0.8 17.4 9 3 12 21 21 21 21 FNIP Repeat DUF1769 PF08588.5 EGC40598.1 - 1.3e-05 25.0 27.1 0.13 12.1 0.0 12.0 6 5 8 15 15 15 3 Protein of unknown function (DUF1769) GAGA_bind PF06217.7 EGC40601.1 - 0.43 10.5 11.4 0.44 10.4 7.9 1.0 1 0 0 1 1 1 0 GAGA binding protein-like family POX PF07526.6 EGC40601.1 - 0.43 10.8 5.1 0.51 10.5 3.5 1.3 1 0 0 1 1 1 0 Associated with HOX Bap31 PF05529.7 EGC40601.1 - 1.7 8.1 8.4 2.3 7.6 5.8 1.3 1 0 0 1 1 1 0 B-cell receptor-associated protein 31-like Band_3_cyto PF07565.8 EGC40601.1 - 2.5 7.5 6.1 3 7.2 4.2 1.1 1 0 0 1 1 1 0 Band 3 cytoplasmic domain Gon7 PF08738.5 EGC40601.1 - 4.6 7.2 10.3 28 4.7 7.1 2.0 1 1 0 1 1 1 0 Gon7 family zf-RING_2 PF13639.1 EGC40602.1 - 2.4e-09 36.8 9.0 5.2e-09 35.7 6.2 1.6 1 0 0 1 1 1 1 Ring finger domain zf-C3HC4 PF00097.20 EGC40602.1 - 1.4e-07 31.0 11.0 4.6e-07 29.4 7.6 2.0 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_3 PF13920.1 EGC40602.1 - 1.9e-06 27.4 6.5 4.6e-06 26.1 4.5 1.7 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-rbx1 PF12678.2 EGC40602.1 - 2e-06 27.8 4.4 6.7e-06 26.1 3.0 1.9 1 0 0 1 1 1 1 RING-H2 zinc finger zf-C3HC4_2 PF13923.1 EGC40602.1 - 4.6e-06 26.5 10.4 1.2e-05 25.1 7.2 1.8 1 0 0 1 1 1 1 Zinc finger, C3HC4 type (RING finger) zf-C3HC4_4 PF15227.1 EGC40602.1 - 0.0021 17.9 8.5 0.0021 17.9 5.9 2.5 2 0 0 2 2 2 1 zinc finger of C3HC4-type, RING zf-RING_5 PF14634.1 EGC40602.1 - 0.0087 15.7 9.6 0.024 14.3 6.6 1.8 1 0 0 1 1 1 1 zinc-RING finger domain zf-Apc11 PF12861.2 EGC40602.1 - 0.011 15.5 0.9 0.024 14.4 0.7 1.5 1 0 0 1 1 1 0 Anaphase-promoting complex subunit 11 RING-H2 finger zf-RING_4 PF14570.1 EGC40602.1 - 0.016 14.7 9.0 0.034 13.7 6.3 1.6 1 0 0 1 1 1 0 RING/Ubox like zinc-binding domain zf-RING_UBOX PF13445.1 EGC40602.1 - 0.1 12.3 6.3 0.38 10.5 4.4 2.1 1 0 0 1 1 1 0 RING-type zinc-finger Chordopox_A13L PF05961.6 EGC40602.1 - 0.11 12.4 2.1 1.2 9.1 1.2 3.0 2 0 0 2 2 2 0 Chordopoxvirus A13L protein DUF1272 PF06906.6 EGC40602.1 - 0.42 10.4 6.6 1.4 8.8 4.6 1.9 1 0 0 1 1 1 0 Protein of unknown function (DUF1272) Oxidored_q3 PF00499.15 EGC40602.1 - 0.97 9.1 4.6 2.4 7.9 3.2 1.7 1 0 0 1 1 1 0 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 DUF1888 PF08985.6 EGC40602.1 - 1.8 8.2 7.0 5.8 6.6 0.1 3.3 1 1 3 4 4 4 0 Domain of unknown function (DUF1888) RhoGAP PF00620.22 EGC40604.1 - 1.3e-36 125.5 0.2 2.9e-36 124.3 0.1 1.6 1 0 0 1 1 1 1 RhoGAP domain EGF_2 PF07974.8 EGC40605.1 - 1.7e-05 24.8 20.1 6.9e-05 22.9 7.6 2.6 2 0 0 2 2 2 2 EGF-like domain Laminin_EGF PF00053.19 EGC40605.1 - 0.58 10.1 15.9 0.021 14.7 5.7 2.4 2 0 0 2 2 2 0 Laminin EGF-like (Domains III and V) DUF3430 PF11912.3 EGC40606.1 - 0.0085 15.9 6.8 0.011 15.5 4.7 1.3 1 0 0 1 1 1 1 Protein of unknown function (DUF3430) Herpes_U47 PF05467.6 EGC40606.1 - 0.08 10.7 0.0 0.08 10.7 0.0 1.1 1 0 0 1 1 1 0 Herpesvirus glycoprotein U47 Arm PF00514.18 EGC40607.1 - 1.6e-11 43.5 6.8 0.6 10.0 0.0 6.7 7 1 0 7 7 7 5 Armadillo/beta-catenin-like repeat HEAT_2 PF13646.1 EGC40607.1 - 0.0006 20.0 0.0 0.083 13.1 0.0 2.8 2 1 1 3 3 3 1 HEAT repeats FNIP PF05725.7 EGC40609.1 - 1.3e-68 226.6 54.6 2e-11 43.6 0.1 10.8 7 3 6 13 13 13 10 FNIP Repeat LRR_5 PF13306.1 EGC40609.1 - 8.7e-06 25.4 0.4 3.5 7.3 0.0 4.4 1 1 3 4 4 4 3 Leucine rich repeats (6 copies) ketoacyl-synt PF00109.21 EGC40610.1 - 1.3e-61 208.2 0.0 2.2e-61 207.5 0.0 1.4 1 0 0 1 1 1 1 Beta-ketoacyl synthase, N-terminal domain Acyl_transf_1 PF00698.16 EGC40610.1 - 4.9e-47 160.8 0.0 8.3e-47 160.0 0.0 1.3 1 0 0 1 1 1 1 Acyl transferase domain Ketoacyl-synt_C PF02801.17 EGC40610.1 - 1.2e-31 108.9 0.0 9.2e-31 106.1 0.0 2.3 2 0 0 2 2 2 1 Beta-ketoacyl synthase, C-terminal domain KR PF08659.5 EGC40610.1 - 1e-22 80.6 0.0 1.9e-22 79.8 0.0 1.4 1 0 0 1 1 1 1 KR domain Methyltransf_12 PF08242.7 EGC40610.1 - 1.1e-22 80.3 4.3 1.2e-21 77.0 0.0 4.0 3 0 0 3 3 3 1 Methyltransferase domain PS-DH PF14765.1 EGC40610.1 - 2.5e-18 66.2 0.0 3.8e-18 65.6 0.0 1.1 1 0 0 1 1 1 1 Polyketide synthase dehydratase adh_short PF00106.20 EGC40610.1 - 9.3e-15 54.9 0.0 1.6e-14 54.1 0.0 1.4 1 0 0 1 1 1 1 short chain dehydrogenase ADH_zinc_N_2 PF13602.1 EGC40610.1 - 4.6e-08 34.0 0.0 1.1e-07 32.7 0.0 1.7 1 0 0 1 1 1 1 Zinc-binding dehydrogenase ADH_N PF08240.7 EGC40610.1 - 2.6e-07 30.3 0.0 6e-07 29.2 0.0 1.6 1 0 0 1 1 1 1 Alcohol dehydrogenase GroES-like domain Methyltransf_23 PF13489.1 EGC40610.1 - 1.1e-06 28.4 0.0 2.9e-06 27.0 0.0 1.7 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC40610.1 - 5.7e-06 26.7 0.0 2.3e-05 24.8 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain PP-binding PF00550.20 EGC40610.1 - 1e-05 25.6 0.1 3e-05 24.1 0.1 1.8 1 0 0 1 1 1 1 Phosphopantetheine attachment site Thiolase_N PF00108.18 EGC40610.1 - 5.6e-05 22.2 0.0 0.00012 21.1 0.0 1.5 1 0 0 1 1 1 1 Thiolase, N-terminal domain Methyltransf_18 PF12847.2 EGC40610.1 - 8.9e-05 23.0 0.0 0.00033 21.2 0.0 2.1 1 0 0 1 1 1 1 Methyltransferase domain FNIP PF05725.7 EGC40611.1 - 2.2e-51 171.5 63.3 4.2e-09 36.2 0.1 9.0 5 1 5 10 10 10 10 FNIP Repeat Secretin_N_2 PF07655.8 EGC40611.1 - 1.6 9.1 10.5 3.1 8.2 7.2 1.4 1 0 0 1 1 1 0 Secretin N-terminal domain FNIP PF05725.7 EGC40612.1 - 6.4e-57 189.2 63.1 7.5e-11 41.8 0.2 10.5 7 2 3 10 10 10 10 FNIP Repeat DUF912 PF06024.7 EGC40612.1 - 1.4 8.9 7.6 2.8 8.0 5.3 1.4 1 0 0 1 1 1 0 Nucleopolyhedrovirus protein of unknown function (DUF912) Secretin_N_2 PF07655.8 EGC40612.1 - 5.1 7.5 17.0 10 6.5 11.4 1.8 2 0 0 2 2 2 0 Secretin N-terminal domain FNIP PF05725.7 EGC40613.1 - 3.3e-112 366.2 139.7 1.8e-11 43.8 0.3 19.8 12 3 12 24 24 24 24 FNIP Repeat FNIP PF05725.7 EGC40614.1 - 4.9e-70 231.2 105.1 2.6e-12 46.4 0.1 10.8 2 1 9 13 13 13 13 FNIP Repeat FNIP PF05725.7 EGC40615.1 - 3.9e-29 100.3 72.0 8.5e-06 25.6 1.3 12.4 14 1 0 14 14 14 8 FNIP Repeat TCRP1 PF14944.1 EGC40615.1 - 0.75 9.7 0.1 1.3 8.9 0.0 1.3 1 0 0 1 1 1 0 Tongue Cancer Chemotherapy Resistant Protein 1 DUF3449 PF11931.3 EGC40616.1 - 0.38 10.2 3.8 0.38 10.2 0.7 2.3 2 1 0 2 2 2 0 Domain of unknown function (DUF3449) FNIP PF05725.7 EGC40617.1 - 2.8e-24 84.8 66.8 3.6e-06 26.8 0.3 11.1 5 2 6 12 12 12 9 FNIP Repeat zf-B_box PF00643.19 EGC40617.1 - 0.00015 21.5 5.9 0.00033 20.4 4.1 1.5 1 0 0 1 1 1 1 B-box zinc finger Acyl-CoA_ox_N PF14749.1 EGC40617.1 - 0.017 15.4 2.3 0.035 14.3 1.6 1.5 1 0 0 1 1 1 0 Acyl-coenzyme A oxidase N-terminal ALO PF04030.9 EGC40617.1 - 0.063 12.8 0.1 0.11 12.0 0.0 1.3 1 0 0 1 1 1 0 D-arabinono-1,4-lactone oxidase FAM91_N PF14647.1 EGC40619.1 - 2.9e-109 364.8 7.1 4.8e-109 364.1 4.9 1.3 1 0 0 1 1 1 1 FAM91 N-terminus FAM91_C PF14648.1 EGC40619.1 - 9.1e-107 357.6 0.1 1.2e-104 350.6 0.0 2.2 1 1 0 1 1 1 1 FAM91 C-terminus Methyltransf_23 PF13489.1 EGC40620.1 - 1.1e-17 64.2 0.0 1.5e-17 63.7 0.0 1.1 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_31 PF13847.1 EGC40620.1 - 2.3e-16 59.7 0.0 3.4e-16 59.1 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_11 PF08241.7 EGC40620.1 - 2.8e-14 53.3 0.0 4.5e-14 52.7 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_12 PF08242.7 EGC40620.1 - 2.5e-11 43.8 0.0 4.3e-11 43.1 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_18 PF12847.2 EGC40620.1 - 8.6e-11 42.4 0.0 1.4e-10 41.6 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Methyltransf_26 PF13659.1 EGC40620.1 - 2.1e-07 31.0 0.0 3.2e-07 30.3 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase domain Ubie_methyltran PF01209.13 EGC40620.1 - 2.8e-06 26.6 0.0 3.8e-06 26.1 0.0 1.2 1 0 0 1 1 1 1 ubiE/COQ5 methyltransferase family Methyltransf_25 PF13649.1 EGC40620.1 - 3.2e-06 27.4 0.0 5.4e-06 26.7 0.0 1.4 1 0 0 1 1 1 1 Methyltransferase domain MTS PF05175.9 EGC40620.1 - 3.9e-06 26.3 0.0 6.7e-06 25.5 0.0 1.3 1 0 0 1 1 1 1 Methyltransferase small domain Methyltransf_4 PF02390.12 EGC40620.1 - 0.00043 19.3 0.0 0.001 18.1 0.0 1.7 2 0 0 2 2 2 1 Putative methyltransferase RrnaAD PF00398.15 EGC40620.1 - 0.00046 19.3 0.0 0.00063 18.8 0.0 1.2 1 0 0 1 1 1 1 Ribosomal RNA adenine dimethylase NNMT_PNMT_TEMT PF01234.12 EGC40620.1 - 0.00098 18.1 0.1 0.57 9.0 0.0 2.1 1 1 1 2 2 2 2 NNMT/PNMT/TEMT family Methyltransf_17 PF12692.2 EGC40620.1 - 0.059 13.0 0.0 0.18 11.5 0.0 1.7 2 0 0 2 2 2 0 S-adenosyl-L-methionine methyltransferase Methyltransf_21 PF05050.7 EGC40620.1 - 0.061 13.2 0.0 0.12 12.3 0.0 1.4 1 1 0 1 1 1 0 Methyltransferase FkbM domain DUF938 PF06080.7 EGC40620.1 - 0.075 12.5 0.0 0.11 12.0 0.0 1.2 1 0 0 1 1 1 0 Protein of unknown function (DUF938)